lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the condensation of two molecules of glyoxylate to give 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).
Sequence:
MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRAAAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEPLPVYKPAASRVQIEKALEMLIQSERPVIVAGGGVINADAAPLLQQFAELTNVPVIPTLMGWGCIPDDHPLMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTQGRKIIHIDIEPTQIGRVLCPDLGIVSDAKAALTLLIDVAQEMQKAGRLPCRKTWVDECQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPQRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSELDNVTEFEEVADSAKDAPTETCFMKYE
The following text describes a protein:
Function:
Important for the use of proline as a sole carbon and energy source or a sole nitrogen source.
Sequence:
MTTPYKHEPFTNFQDQNNVEAFKKALATVSEYLGKDYPLVINGERVETEAKIVSINPADKEEVVGRVSKASQEHAEQAIQAAAKAFEEWRYTSPEERAAVLFRAAAKVRRRKHEFSALLVKEAGKPWNEADADTAEAIDFMEYYARQMIELAKGKPVNSREGEKNQYVYTPTGVTVVIPPWNFLFAIMAGTTVAPIVTGNTVVLKPASATPVIAAKFVEVLEESGLPKGVVNFVPGSGAEVGDYLVDHPKTSLITFTGSREVGTRIFERAAKVQPGQQHLKRVIAEMGGKDTVVVDEDADIELAAQSIFTSAFGFAGQKCSAGSRAVVHEKVYDQVLERVIEITESKVTAKPDSADVYMGPVIDQGSYDKIMSYIEIGKQEGRLVSGGTGDDSKGYFIKPTIFADLDPKARLMQEEIFGPVVAFCKVSDFDEALEVANNTEYGLTGAVITNNRKHIERAKQEFHVGNLYFNRNCTGAIVGYHPFGGFKMSGTDSKAGGPDYLALHMQAKTISEMF
The following text describes a protein:
Function:
Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MTILQLFASLTPVLSVMIFLVLLRMPASKAMPISMVVTAIAAVFIWQMDTTLLAASVVEGLLSAITPLTIIFGAVFLLNTLKYSGAMDTIRAGFTNISADARVQVIIICWLFGAFIEGSAGFGTPAAIGAPLLVLLGVPPVAAAVVALIADSACVSFGAIGLPVLFGMEQGLIQGGVSMAAEQFAAHGGTYAGYARYIVMHMITIDLITGTLIPLVMVTMLTGFFGRNKSFKEGLAIWKFAIFSGLAFTVPAWIINYLAGPEFPSVIGALIGMAMVIPVARKGYLLPKTPWNDFAENDNQDGVKLETTAKFSQIAAWTPYIIMAALLVLSRTVAPLKAWLSGFNINWTGLLGTELKASFATLYAPGAFFVAVCILGFFLFKMKSPAIKQSIGVSCKSMLPTIISLGASVPMVKIFLNSGANGAGLASMPVALADMLASSMGAVWAWMAPIVGIFGAFLSGSATFSNMMFSSLQYSVADNIGMNHTLVLALQGIGANAGNMMCVMNVVAAATVVGMAGRESEIIRKTMPVAIGYALLAGTIATLWGGF
The following text describes a protein:
Function:
Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia; Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
Sequence:
MLHGDISSSNDTVGVAVVNYKMPRLHTKAEVLDNARKIADMVVGMKVGLPGMDLVIFPEYSTQGIMYDSKEMYETASAVPGEETAIFAEACRKAKVWGVFSLTGERHEEHPHKAPYNTLILMNDKGEIVQKYRKIMPWVPIEGWYPGNCTYVSEGPKGLKVSLIICDDGNYPEIWRDCAMKGAELIVRCQGYMYPAKEQQVLISKAMAWANNVYVAVANAAGFDGVYSYFGHSAIIGFDGRTLGECGEEDYGIQYAQLSKHLIRDARRNGQSQNHLYKLVHRGYTGMINSGESPRGVAACPYDFYKNWIKDPEGTRDMVEAMTRSTPGTDECPIEGIPNEAAASNY
The following text describes a protein:
Function:
Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
Sequence:
MTFMNAMYNFFNRHRRKIIISSAIAGGVVVLVKYSQWRLQKYIEGETTLQMTRARMENHFNNNQKTCHLTSKTNSSIHTLISILTIISLLPNLSEAIEKEINLDELTEKLKARPPNRLQIWENLKTLTFTQVVTKLYSVCMLTILVRIQLNIIGGYMYLDSTNDKETKNADSDQTYASARLQQRYLSVVYYLLGDGMKEFIKVVKDTISDIVTNLSLKKEVSLGDISQLFQRIRMVLHDKLCQANQDSKSFLTSFMIPPNDEISDSFESLQENQLFSKLMSETRDMIESQDCIKVMNHCLDFGFNTFMDKVDEAVKQQVTSKNIEITLAVAKLLPVVTSQLKVMMKESSNTSNSFLQLIRLIVCNYAQNTRKMSREIDGSQIN
The following text describes a protein:
Function:
Histone chaperone-dependent acetylase that modifies 'Lys-56' of histone H3 (H3K56ac), which occurs predominantly in newly synthesized H3 molecule during G1, S-phase and G2/M of cell cycle. Histone H3 'Lys-56' acetylation is required for S-phase-linked DNA damage tolerance and proper silencing in pericentromeric heterochromatin.
Subcellular Localization:
Nucleus.
Sequence:
MPDLWSESILEGRKLSIYHLKSTLEKCPFLFGQSKKSKDFQFGSHLFLVEEQNVFIFGMECIVYEKNKEFIVFVSKADSTGFGSKGVSCNSLAFCCLVTLIDGLRKQGAENVTLTLFAIAQGQYLFPESVDNGQKHVLNDSGLLRWWVNCLEKLRKYYTDSEAPNDSEKQKNSTLLPKAYLFVPGLENIRSYLPNRHWIESNAITTGKAVEELPRFPDDPKCRYLCELQDEKSDMSVEEFWDTLTYRQECSSGKLVGFFTLQLQFYQTREFIAKDNFGDSGVMIPAKLYRVTYDTLLKHPFGSLSDAQSSTEKFLSNTLSAVQNLKDFHYKRYKLDICGLAKRDDRKNHNHSKPATQANILQPRKKVKK
The following text describes a protein:
Function:
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Sequence:
MASETKSLGGMQRRAAGNRAHNRMVLQKLVVFSILMAAVPMATFYGVHSFFRPGELLDGGLSSPGSQYADAWSGFTAVLSVNIVIGLYILSAWKEDDGKEVAPPVGRFAKAKEQ
The following text describes a protein:
Function:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Sequence:
MSYESATSSSSLICGLIQSSWHVSVCGSFVLLGFTVSILSGGSSGMEVYDVSETRNHDADMIEGADLNSHFTSPNIERTEVMINEGAPEFFVDQNLYYPAATNYGYYCSGFGTPGEQEDQHRIFGVDGPNIQFTGAQNESFPYVYYSYGYAQSPYNPYNPYIPGAMIGADGSFGGGQHYYTLPNYQSPVSAPGYIPLVQPDNFSDSSADSFFGASASVSKPDGRGLKPKFNSASGNFSRNSSIFLSNQTSSLARASERPRANDGRKQGLTHASVSGSSFLNLASPAVHQSAVAKLRPKLHIGKAVPNGGNGSSDVLGEQNRGPRVGRSKHQLSVKAYTTMAGDGNEQGNIVIYPDQYNMEDFPLGYENAKFFVIKSYSEDDVHKSIKYNVWSSTPHGNKKLENAYEDAKKIAAEKSEVCPIFLLFSVNASGQFCGVAEMVGTVDFSKNMDFWQQDKWSGSFPVKWHIIKDVPNPNFRHIILENNENKPVTNSRDAQEIMYLKGLEMLKIFKNHTLKTSLLDDFMYYENRQKIMQDEKAKFLVKSFDSPIFVPVLEAPQKLNFFVDVPTDNYEKNLKPKDDSDGLKHISFSSPEQIVGNSDVTGIKHAHDEKDEKIAVDKEHISSILKIGSVTIAPKQVEAKQSVSNGNKEPVDVLTVGSMQVKVNGFPSSSGFLKVGSTPFDARALQPGKGDAAVKSGSQR
The following text describes a protein:
Function:
Has transcriptional repression activity. Acts as a corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases.
Subcellular Localization:
Nucleus.
Sequence:
MKAIKDEVVPLQLGLKRAPSFPHCLQPGVSRGKAPQGHLFPEALRGPFSQFRYEPPAGHLDGFPGAFEGGGSRRRKSVPSKVPCRPPAEDASPGPPPPPPRPACASRMIDLCHVGLQPGRPPEPPEPPERPWPAALLPAPYAYLPKGPPGLVLPLFVPAPAFPFGRHAFLPPPPPPPPPRRPEAPPRADRVDVNVRVDDSYLVDVGGAQKRWQCPSCDKSYTSKYNLVTHILGHSGIKPHACGRCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSDVKPHNCRVCGRGFAYPSELKAHEAKHASGRENICVECGLDFPTLAQLKRHLTAHRGPVQYSCSECDKTFQYPSQLQNHMMKHKDIRPYICSECGMEFVQPHHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCYKSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHMHLHSDSKPFKCLYCPSKFTLKGNLTRHMKVKHGVMERGLHSQGFGRGRLALAPAAAALGGLEQEEPFDLSQKRGPGVPQLQPAGEGSRASCRPQQEEDDPRREPRRHSPGPQHPQQPPCAAGQAEGEAGTEAKARGRDSAGPEGGPERERDRDRARGEERLRPRALLGARRGPPFPDYLYFKHRDESLKELLERKMEKQAVLLGI
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus.
Sequence:
MSNPINFSQLTAQQQQLLFQQQQQQLFLLQQQQQQQQQQQQQQQPVPSVQPQLKSRQSTLGLPSRKPPAAPQPVQTNQPQPTPQPTLTPQQQQILLQQQQYQFSNNAIPSSRHSIIGPSSSANRQSLGPPTVYNNNATNNINIRSTMLPSQNFNNNNNNSNVINNGGNSSMGGRISTISTTSSTGTIGSNLNSNIKNKEGKKSIGIKNAAPQQLRQENRPINDGKFQQNCLSKIQQFLSRSEKCYPKQINKDNISNEIFGIMKFLIHFIDPHFKLPPDKQEEEIIAFFKRMGYRSSGFTKRAFSTVPSVHNKGHLLGALVWIIELIEYDQEVRFREADIEKDILGDDEISIKMFSNQVFKSYESFLQDVEGDNRVDIFLESRYAEANEKIIREKEESLERQKKFKQEIQKLNEFLANDDIERYNSFIETTTQDIIAATDQINVYEQDNQELDNIILDNEHQYTSLEDHLSDLKQRKKDNESRILIQQSNLVDARRINQERSELQEELDKVNNDLSRQDQMKQEIARDIKHSVTNIEEQIQTYKEICCKASLVTDNNMIIEKYRINFSAPSDGEVSVSDLKQVIKNLKQLNNDLQNSSRTIKTELQTNNNQLEALKETIKDKDLEVARIRQKFEKQKESLKNEKKNQNLDIQQREENIELLQITNKKNLDDGRSDLEKTQRLFEQHKEEYKRLKHELEQTTDTIKLNYTTRIQRFVQHRQFVGNQIYETVKQMEELSNTQKKLFPPTQQQSQLQQHSQLQHSQLQHSQLYHSQNNNNNNNLQSNLSSSVIGISDS
The following text describes a protein:
Function:
May be a regulator of keratinocyte proliferation or differentiation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAGSLKNPAHFMKPLSSHGVGTPPYKLLPPSALTVPAKVAPKVTGVSGEPMAPKEDGKQSSLKPAHQTSPASQHEKETQVTLQPEAPAVIPQGATGTPLPSPSYSPYHHHHPPPQAPHLAQPYPPPPPPPPSHPGPDPHHLLELQRQTDMIVSRQAADIARLKTELSTQEAQHSGELARSRAGSRESRVGLEEEVLRLKQELKRCNASHKQQVSNMGEEHQRETIHLTEKMRKLTEDLHSVREESDGRNANLTTRLAAEQKSSSEQKDQLQNDVRQKQEEISRLTTQVAQQKAYIGDALPSSRTSAQWNIEKQNYDKKLKLLEEEKENIQTTADMLNVRLSSMQEIMAIQEKEMTQVQETQHDVTDKHPGEILLTKWREKVFALLVQRKSLEIVLKKDASTHGDKLHSLEGELDGSLNKVRILEHALADKEAQLQLEKKNVTKVEHELVSVQEVAGMLDSRLQESETCLCRMRDMVIRCHKYSNGLDMQSKEMVSRLNSHQQRLTFAISRIELLQDLLARKDSMLKLKVRGSSLQGYSDLSTQTDDQGLNPDSSAVPMELKAELERLQKERDSLASRLKEDSAVFQQRIDDIREEMMEKTDKYEEENNQLRARVIDRGKEVESLEEQLSASDKSLTEAREETVRFRTDLARSQLVAEGASDEKCKLLESQHTERLAEMEKRLNEARREHAKAVVSLRQLERRHTREKERSSEALAAQEDYLTKEISKLKTRLSEVEADRNMLMVTLRQEGLLATCRAKQTGDIPSLIEKENGSCAGGDGERSDNHSISPTNHDRHPPDRGREPLHAVLKDLQTIAAKVLEDDDDDDEVEGNEE
The following text describes a protein:
Function:
Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays GTPase activity. Involved in the ribosome maturation process.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MAPARRFSARLRTVFQGVGHWALSTWAGLKPSRLLPQQASPRLLSVGCADLAKHQKLPGKKPLSEKKLKRYFVDYRRVLVCGGNGGAGASCFHSEPRKEFGGPDGGDGGNGGHVILRVDQQVKSLSSVLSRYQGFSGEDGGSKNCFGRSGAVLYIRVPVGTLVKEGGRVVADLSCVGDEYIAALGGAGGKGNRFFLANNNRAPVTCTPGQPGQQRVLHLELKTVAHAGMVGFPNAGKSSLLRAISNARPAVASYPFTTLKPHVGIVHYEGHLQIAVADIPGIIRGAHQNRGLGSAFLRHIERCRFLLFVVDLSQPEPWTQVDDLKYELEMYEKGLSARPHAIVANKIDLPEAQANLSQLQDHLGQEVIVLSALTGENLEQLLLHLKVLYDAYAEAELGQGRQPLRW
The following text describes a protein:
Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSIGTGYDLSVTTFSPDGRVFQVEYSGKAVDNSGTVVGIKCKDGVVMGVEKLISSKMMLEGSNRRIHAVHRHAGMSVAGLAADGRQIVSRAKSEAISYERVYGEPIPIKELADRVASYVHLCTLYWWLRPFGCGVILGGFDRDGPQLYMIEPSGVSYKYFGAAIGKGRQAAKTEIEKLNLSEMTCREGILEVAKIIYGVHDEAKDKSFELELSWVCEESNRQHQNIPDDLMEDAKEAAIMAMEEMDAD
The following text describes a protein:
Function:
Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.
Subcellular Localization:
Mitochondrion.
Sequence:
MAAALLPETAPRLLTPETLRTAAKQSQGIHLVPLSLRRAIKRYLRDQDRAHMNRKVLLLSASFDRAKGTGAELAAAATRAALLDDPNAPSGAEQRSARWKVRSAYGDIGLRYREDETVAYVASRMPAIYAACHRVLREVRRRLPEFAPAKVLDFGAGPSSALWAMRAVWPKSIERVNLVEPSKEMQRAGQSLLDNLKGLPLIHSYDSIQELNRKIEKHERGHDLVVSSYALGEIPSLSDRITIVRQLWDLTSDVLVLLEPGTPQGAKIISQMRSYILWMEKRKCRKIEKSSSRPPSSMKSIVAQKVSLKNGSFVVAPCPHDGRCPLENSDKYCHFVQRLERTSSQRAFKRSKGVPLRGFEDEKFCYVALRRGKRPEEAWPLDDLNFETLKERNAKRKPEDLVIDYDDQFPSEEDEEVHVDGGDSLVPYASDEHELSLFHDSEEAEAEQTVRADLGGGWGRIIYSPMRRGRQVQMDVCRSTKRDASEGTFERVVVTRSKNPTLHFQARKSLWGDLWPF
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MEKESPFGLSHICVLLTALMAILPLSQGNWMWLGVTSFGVPEKLGCTNLPLSFHQKEMCRKKPYLLSSIREGARLGIHECRNQFKHERWNCSVSPTISSASSSFSLSFITSSLASAHTIFGYELSSGTKETAFISAVTAAGLVHSVTRACSAGNMTECSCDTSLQNGGSASEGWHWGGCSDDLQYGMWFSRKFLDAPYKNSSGRDSDVLNAMHLHNNEAGRQAVTKLMTVDCRCHGVSGSCAVKTCWKSMSSFEKIGNFLKNKYENSIQIADRLKRKVRRREKNDRKIPIYKGDLVYTNKSPNYCVEDPKLGISGTHGRECNRTSEGSDSCNLLCCGRGYNTHVVRHVERCECKFVWCCYVRCRRCESMTDVHTCK
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus envelope.
Sequence:
MSGGPQLQLVVLWPWLLMASLQAGLGRTGPALAAAVESERTVVQKAIIRVIPLKVEPIVLEGEFASVAEVTPAEGKLLQSHPLSLCNTSEDEHTESGFITIVKLEQPDRDPNPCLSLANKAKLAGERGARAILFDITDDESAADQLKKPRGLSQPVVLIRGHDAELLMGVVNKNREAHVKIEVKEPPAWPDYDVWILLTVVSTVVVIILIFVVRTKCQLNRTQDSVQQQTMQAIGQLATRRYQARCRQASWWDSASSCSSAPVCAICLEEFTEGQELRIISCSHEFHRECVDPWLQQHHTCPLCMFNILARDSVDQATVAGSRLAPRDMEPGRRLHLFRQHPGHSLYHLPHPYPQRNLRSFPSEPAHSNPFFHSPELSQLDFGTIHYVPYRPASSLPACGHASPLASSLRGQQHPNPPACGQPPHRTCSLQPTPPCLGLKAALAQRQHRAPVPRRGVSHGHQHNSSGSGESYLTEHSGYLADGPGSDSSSGPCHGSSSDSVLNCTDISLQGIHGSCSTFRSSLSSDYDPFVYCSSDGPTMDNGPERQRALRETRPRSLDLMVPGGAAPAKAQVLNHIHYHHHQHHHYRRDVECPPGRAGPGPGQRKSRYSGAKVGFHSARTQKRAEKSHHCQQPLESRTELQEAPPVGQPASPQQGREPPHAPSASPNRLDFGVDANRQSGAAGTSPVLLPQRHSLQSRHHRRKRKCPLELDPALLPEDSALPNHIPHSHPAGHRCSPEVQPLIPSSPMPCSTGSRPLWKCLVPPSSSELKKQEEGMSGREGNHAVPAGFSGTGTPRHSLHLHCPAQQCKQGESALGPLFWQADDEGGLLQARWEGAPGACRLSCRTTGDRGRLELSYPQVMTGTFGTC
The following text describes a protein:
Function:
Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Interacts with EPHA3 at the cell membrane.
Sequence:
MEMEKEFEQIDKAGNWAAIYQDIRHEASDFPCRIAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQKEEKEMVFDDTNLKLTLISEDVKSYYTVRQLELENLATQEAREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHVPPPPRPPKRTLEPHNGKCKELFSNHQWVSEESCEDEDILAREESRAPSIAVHSMSSMSQDTEVRKRMVGGGLQSAQASVPTEEELSPTEEEQKAHRPVHWKPFLVNVCMATALATGAYLCYRVCFH
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MADEVDLGKKRSHDPEFKGPIEDRSCTDIICCLIFVAYIVGMVVVGIVAFAEGDINRLLLPTDSQGKVCGKDPAYLDKKYLVFFDITKCIPKGIPSLSNPKCYTPQVCVSKCPTKNEAGTSRDAADMICKPGVVPKDNLNDKLTLIKEGKCVPYYLASSPVLFRCVPSLVDLNSVFDSATNKNVSKSSVEQGIGGFVISMVLAFVYIIITRWIAGPLIWFTIIAVFALLVFGMYCCFSKYKELKDSGKSKTLEFTADLSKYGDSKETWLALGKYLSLLMEGLHGRGEPISKYDGIGWEPISKYDGIGEDEMKLNRIRIAVELIGEASNYLATNGVPQYKVSNLPDDPYNLTDGTTCDPATFDSKYPNTSSSCILVGYKENDHLLRMQVFHFFGWLWIMNFIIALGQCVLAGAFASWYFAFNKPDDVPMLPVLSSFSRTLKYHTGSLAFGAAIIAIVQFIRAVLEYIDRKLKESGHDNKAVKFIMCCCKCCFWCLEKCLRFLNKNAYIMIAIYGKNFCTSAKDAFQLLLRNILRVAAVNSVTSFLLFLGKVLVTSIVGVASYYWFRKIDADDPDSLNYDVVPVIISVVFAYVVTVMFFDVYDMCIDTIFLCFLEDLERNDGSAEKPYYMNDDLKKILNKQNRASTEQLDQEK
The following text describes a protein:
Function:
Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine.
Subcellular Localization:
Cytoplasm.
Sequence:
MEVAEPRLLACGDNTDQQQSEQRHHREGHRPLVTPAVALSLAWQLFGLAPVAASAPCSAIEPCIELPSYDDRNFLIVLDGGGSGSSSGNSSGNGSSSSSSAGAGAGVASSVDAADGGGGGGGGVGGSGSEAGRWGRVVLKIHNSRDNERRAQLQAMDEAMLRLAAAGVATNTPLQPCPPLTPSPPPPPAPAPPPPASSQQQQEQARPRQCNGGGSGSSSGGEAVHVPCLVAAAPPPGGPGATATASAGANTADSYGYGSSSNGADADVGAIGATGARAGVAGLSGWAWLPCTCCSGGAAEAEVAEAAAEHYHWHAVRCLSYVPGRMMSAVTHLTPGLLVSLGELLGRVTCGLSGWRPPALQGATHDWHPQMGAAVLRRLVPHIGAFEPERKLLLLQAAADLEAAADMLSDPQRLPRQVCHADANDDNVVITGPDSAAQAAGVIDFGDMSEMPRVCEVAISSLYAMLLALQRPMRPPLRTPEEAAGFLAGQQQGQQHGQQQGQQGGTVEDAVPGAALGEGVEGVEEESDKALLLRLLSAAGLILAGYSRHVVLQPSELSALPLLLRARLAQSLALGAASVVADPGNAPYLLMTQGPGWRVIRLLQPGALMSQSELLGALLRAARLQ
The following text describes a protein:
Function:
Cell cycle-dependent nuclear envelope component required for embryonic mitosis.
Miscellaneous:
MISCELLANEOUS: The OPA repeat-containing and the Ser/Thr-rich regions might be involved in protein-protein interactions with the major protein-rich layer of the nuclear envelope.
Subcellular Localization:
Nucleus envelope. Nucleus, nucleoplasm. Cytoplasm. Note=In the nuclear envelope during interphase to metaphase. And in the nucleoplasm and cytoplasm during anaphase and telophase.
Sequence:
MSFSNVLIMRQPDEGKCHICKRVFCCGKCRQKHQFKAHAIAVREPLGLRSAGGGIIEHRHQMESGATTIYVFCPICERRPLLLREEMHGELLAHIETCHLPLRCRKCQRNYTRVDDLREFSKCVDQQQSCTDVTGATETSKATLKKAANSTAISTQTSPSVTPISLINMRWKAKSRVTHEEFISDSVSSIRNLSSFSNSSIRRSIGQLGVNPSETMEKGKVIRSTSTPLHVESVFAKPKEPITFNASTGGHVSSIYHEEPSPTPESNPVQQQQQQQQPLQQRAWKMGARNKMSAATPLRQVMSKSIQKAFVEHGGMMVHQPPSAVVQRRVRLDLSEHSSHEAAGSSALDLRLSPAMRRTQSESSASEVNSGSSSSYSTSRNADLCKRQFLLSAQKLTTESIIITRTNSSSQKTSSTVYNSCESVEIIRSTSESAEVCHVPAITPIRVTGAGINKKQIKFETPPKSSQQMRSNGEGDETKDQFFTPEPGTPEIPERRHRQAIVPRQLSGEFSPKKDKPKEKGLAVMALISPPLQQPRVRPPLRECRQQRVYSGVQDVGEPEVVDAEEEDEVFRPTNASTCNDKKLEAPNSGRLWSLMSSMMRLPASLRGEREKDRDRDRDSDKENAGSGSLIRRCASIAGSLVRPSARDSSMEDQQCLKRKRTQTLDSQYCSPLSPSSSSKRYRIRPREPIERMRRQ
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MSEYIGAIEIRGGTFKKFTKVQMECKNDYLKIYHQGDRSKEKISISMSVAIFHKKLTWLKKFPKEQEELAFEIAYDKLYQFICPNYIEYSTWLNIIPLKMRCNEVFGVPLSVGVKKSGWRFPLPIYRCLEYLEKNDGLKTEGIFRLSSSIDETKRIKEIFDGGQDVTMQIIGDVHVAAGLIKLYLRELPDSLIPKSMYNTFLELPTSSDLNNDIKKQIQTFPDINKNTLWLIMRFLSKVIQNTSVNQMTSTNLCVCFSPSLFRSPDNDMTREMTDTPKLRTIIDSMITHFTDIFYDIEKENHKLGIIPPTYPAIIPISSISSEMISDAVNKRNKSLVSKIEKTNTSLNSNTSETPITSKPLQPVMQSVYDSQHQKYQSTSQQQDQSIPNTTFLPSKSRNAFLQHLNQSTTSGPRSSQFGTSSPNGFLSRQYSHNTTNQSSGSTINIGTRNSPTSPIRNVETPDEVQQIPLIPHSEQLTPSPPCTKSPEQQQKAKFNAFAGARITTRCASQYHVHDTSLQALILPPINDNMNDAQKVQSLQRRVDALISKAIEQDKIIYEFRQKLIALGVTEEEIEMLSIQKSPSPTNQPRRSVLFRPTDKSAARGTFLGRGRTQQTQTQTPTQPQQEPSVEEEY
The following text describes a protein:
Function:
Component of the A-type ATP synthase that produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MEGAELIIQEINREAEQKIQYILSEAQKEAEKIKEEARKRAEDRAQWILRKAKTQAEMEKQRAIASARLEVRKKRLEVQEEMIRAVLSALRERLASLPADEYFQTLVTLTTEALEELNIDSAVVRSNEETLKLIVEKLPEFKKSVSEKLGKEVEITVGEPISTIGGVLVESSDGSVRVDNTFEARIERLEADLRARIAKALFG
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MSNQFLECSKIEKDLLSSDKISNDDVFSSSTTLVTKKDLEAPERKSNYAPHELVAQGSRLAPKVSEFVEGQRRIGGTAHAEKLVLELNAASQINRGPPGAFASSRLHLDMLLGRDESYSFGDYLGGYDKEQKCTGSHRVTVAAEYGSHEPITQHALVSNQNIPKPNPLHTTFKNHNFPANFLNETNVLDYFCNPDNIFYDMKSCNQVIRMQQIGRPLEECLQSMAGEQYVLHFARPPLFVICKQQRNLGINQNIVTPLAYYYIINGTVYQAPDAFSLVQSRLLGAVAPLGQAFEQMLKFSRFNVAKGYSWEFDKKPAPEGDEENDDEEDEALLRGGTSKKKADSDEAAHIAARSSTFQEQRTTNILQVRTGDTVGRRGVR
The following text describes a protein:
Function:
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
Sequence:
KTTCSAALLSKHLKKCNAKAKEAHEYFVRNINSGLPKPEGSQNSTKLFLKDVSDEELLATIEKLERISEALADRPETYVGLHEGLSAELDELSDCAVAQKHLRQKAALLGLAESRGLLGEQACYVEFGAGRGRLSYWLAKILSGKGCRFLLVDRASSRHKFENKIRREEQENSSEIRRLQIDIEHLCLGNVDLVKVHEGRLVGLCKHLCGEATDFAIRCLVETTGKTSDSGAATSALQGLLMAVCCHHRCRWASFVGRPFLEQVGVSERDFELLTCLAGWATCAARGTFQCTSRRRQSF
The following text describes a protein:
Function:
Class-III neuronal intermediate filament protein. My form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network (By similarity). Assembly of the neuronal intermediate filaments may be regulated by RAB7A (By similarity). Plays a role in the development of unmyelinated sensory neurons (By similarity). May be involved in axon elongation and axon regeneration after injury. Inhibits neurite extension in type II spiral ganglion neurons in the cochlea (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell projection, axon. Perikaryon.
Sequence:
MSHHSSGLRSSISSTSYRRTFGPPPSLSPGAFSYSSSSRFSSSRLLGSGSPSSSARLGSFRAPRAGALRLPSERLDFSMAEALNQEFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQELRELRRELELLGRERDRVQVERDGLAEDLGALKQRLEEETRKREDAEHNLVLFRKDVDDATLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALRDIRAQYENIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISVPVHSFASLSLKTTVPEVEPPQDSHSRKMVLIRTIETRDGEKVVTESQKEQHSELDKSSIHSY
The following text describes a protein:
Function:
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Subcellular Localization:
Mitochondrion. Nucleus.
Sequence:
MIFDRTIPSVKVFLLLLFPNRSFTPSPIMSSKRKATTNPTNDTKKPKANGSITSFFGPPKTVSSTTKVTGTSTDTIAPAPATFKFNKEKWVATLTEEQKDLLKLEIETLHESWLAVLKDEIMGKEFLELKKFLKKELEGKDKIFPPMEDVYSWSRHTPFNTVKAVIIGQDPYHNFNQAHGLCFSVRAPTPAPPSLKNIFKALAKDYPDFKPPPNNGGLLTPWADRGILLLNTCLTVRAHQANSHANHGWEKFTQKVIDTVALKRTKGVVFLAWGSPAGKRVAKVDKNKHCVLMSVHPSPLSASRGFFECQHFKKTNEWLKERHGEGAEIDWSLDVPAVEAGV
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MESPDIRGGDGSDFATLETAEKIILRWDSTTSEEAKENLIFQSDREEVDRYLQAVDEVQRLVSSVSISDSDSRHEDELRNILLSQTSTFEPDSLLLDSSASSFATRADLEDTETAPPDDAEGEEQEEMNLVLPDGSDSNSGSDPGSSRLSSRRSSCKSTSSIREIDLVSSEAVSDLRSIVRRMIGAGYSRECLQACVRVVFASEKRLCEQIFDGGEVEETCFMEIVKSSALQLLTFPEAISISRRSPEKLFKILDLHDALADLLPDMEEIFNSESSETILAQATEIQSRLAEAARGTLVEFENAIFREPSVVPVPGGTIHPLTRYVMNYLNLIADYKQTLVELVMSKPCAVQKVKSSPELREIIGDFYLRRLTGIFRHAATKYQRATWVRVLNSLRDEGLHVSGSFSSGVSKSALRERFKAFNTMFEEVHRVQSTWSVPDAQLREELRISLSEHLIPAYRSFLGRFRGHIESGRHPENYLKYSVENLETAVLDFFEGYTTAPHLRRSQ
The following text describes a protein:
Function:
Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in ribosomal protein rps2.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MLVKPMACYFEIWTRKVTTIEDFSLAIANRFKQMGSHSDSEVDWDNEEEVWEDEVHEFCCLFCDSTFTCLKDLWSHCKEAHNFDFYQVKQQNNLDFYACIKLVNYIRSQVKEGKTPDLDKLSDILRSDEYMISVLPDDSVLFSLGDELDSDFEDDNTLEIEVENPADVSKDAEIKKLKLQNQLLISQLEEIRKDKMNELTSQTTDQLSVTPKKADNDSYYFESYAGNDIHFLMLNDSVRTEGYRDFVYHNKHIFAGKTVLDVGCGTGILSMFCAKAGAKKVYAVDNSDIIQMAISNAFENGLADQITFIRGKIEDISLPVGKVDIIISEWMGYALTFESMIDSVLVARDRFLAPSGIMAPSETRLVLTATTNTELLEEPIDFWSDVYGFKMNGMKDASYKGVSVQVVPQTYVNAKPVVFARFNMHTCKVQDVSFTSPFSLIIDNEGPLCAFTLWFDTYFTTKRTQPIPEAIDEACGFTTGPQGTPTHWKQCVLLLRNRPFLQKGTRVEGTISFSKNKKNNRDLDISVHWNVNGKADSQSYVLN
The following text describes a protein:
Function:
Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity).
Miscellaneous:
MISCELLANEOUS: Incorrect gene name (LUM) has been attributed by Ref.1. LUM and FMOD are two different genes but members of the same family.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
LDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYLEHNNVYSVPDSYFRGSPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKI