lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Essential for magnetosome formation. Can be used to induce magnetosome formation.
Miscellaneous:
MISCELLANEOUS: This bacteria makes up to 20 cubo-octahedral magnetosomes of about 45 nm in diameter which contain membrane-bound crystals of magnetite (Fe(3)O(4)); MISCELLANEOUS: Expression of just the minimal mamAB gene cluster (amb0961 to amb0978), including this gene, is sufficient to form a minimal magnetosome chain with small magnetite particles; MISCELLANEOUS: There is an identical gene in the genome (amb1005, AC Q2W8L6).
Subcellular Localization:
Magnetosome membrane; Single-pass membrane protein.
Sequence:
MALGDANVGSAPGVDFSALQRVKQSEELLAQLYVVEETPRRLGRGPVHALMVISVLSVVAFIATLLMRYNTFVTMSEDTQAKRSNYEVMIQRRDNLFGNLVKLTLNHAALEHSIFSHTSDKRTEGVEAGKGGPIGSALEQLMKQGGIGKLLGDIGGGKALLGADGGFGNALGRLMAVVEQYPTIQSVDTYKHMMTSLVEMEDRIATRREDYNAAASTYNIEITKWPWNYLAFITGFKRAEYFQEKPAGDTPIITPQLFQELLPLNHAQDIKK
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSYRLSFAISILKDQVKDEVVGYKFYKQGYKFDFQPPKDLADQLVGAMFYVIGYFMGQQGAWGCLKYIPHCKDDHRFIEQHRESRSKNAQTEKLMNAKPDETTNKAQQMTIFYHREVIVFDNIPADRARDLMLAAKDYPSSTGKTNAHDYLIATSNFPYNARESDQPIDHLRVQANGLDLLIARRASLNKFLAKRKDRATVQAPYPSPGAGPSMHELNFDINM
The following text describes a protein:
Function:
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
Subcellular Localization:
Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery (By similarity).
Sequence:
MAEGEITTFTALTERFGLPLGNYKKPKLLYCSNGGHFLRILPDGKVDGTRDRSDQHIQLQLSAEDVGEVYIKSTASGQYLAMDTNGLLYGSQLPGEECLFLERLEENHYNTYISKKHADKNWFVGLKKNGNSKLGPRTHYGQKAILFLPLPVSAD
The following text describes a protein:
Function:
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
Subcellular Localization:
Nucleus.
Domain:
Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors; The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.
Sequence:
MGDSLGLIGKRLLLLLNDGSSAPAATGGEVERAAWLRGTVRAVSVIGLASPGVEVFVEFEDSPWRKRAWVQLYGDEVRVVLMESAIVWANCSDPSLSTALGSSATQWPALMFKQLIDRVGLGSVVPVEFFGARNLAFLPNGNSLHTFETEKDFTHSLLQEQPALQHAISSWHTDSELQEILRKGSYTIQGRRVKVYQPEFEQPWAFGLVSQHDPVSHIMEITMDQSCLKGEETQVVDPRVIHVMLAEGKLNESQDRRKKEGDGGKGEGSRRRRTASEGDEDITLKRFKGAGEGASDNQNGNSSNRDAEAMVTCVEMPGKGVVEGKDEAGGLGGRVTSTCSPVALSSQDSSNNSNSSQQEHSHIRSTGFVKENGSFIPNQERISSVSAVLPASTPTPPPLKPAPSPFSNTFPSLGQMPNLVPGAPAPKSSPTLPSSEREEGGVLSGYPKTAALVSPGPVTISSPSQENTSSVALTAPVDANQKPSMWGSTSEGNQTPKAPVLAPAGFGKQSSGGVFGNVSTQTNGSSQGDKPFGFSFRGAKDSQRQDSDTSQNLFFQFISQNQSNTQGQSKAFTSLSECLNKEPPSLFKSAAPSEGFKKTVVASASTGLFGSAPASGLAPLKEQPKVPDIKPAGNGILMNKPFGAVGEAQSKLPATFSSAIIQAASSTEVLKPSGLGTSGLGNASGGIRNVNSSTPVSSFGLLAGNKVSDGHENLFLQPSKETNSFLAYGRGVPQTPFGALTSPKSSSAQSASAVSPSGSTSLLGQDPPGSDAKPNLFTMAEPPKGILAPQFAAPALMTTPSFTSVAQDGQQISKPNREGSDDSSGTLLSTEAEGVSVPFEQSKFSLEERLQSIKKDSESSSNSDLSDLSEGEDNAGQSQKPDLPAGNEDKNKAQAAAKSRPRSKPFKVGQSVLKDQNKVRRLKQSGEAFLQDGSCINVAPHLHKCRECRLERYRKSREQDSDDDDPNVACRFFHFRRLAFTKKGVLRVEGFLSPQQSDSMAMGLWLPSITIQEGLDLDTSKYILANVGDQFCQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLRKNRPPEVEDGPEEEVFSWLKCAKGQPHEPQNLMPTQIIPGTALYSIGDMVHAARGKWGIKANCPCTSRHKTLMRPSAPNGLSQSGAAHSSGNGTTSTSSTTRPNEESAAGVVVKTEPVEEPTSADTTSSTSGTNSSTSSPAPAPTSAPTLLPPSLPPPSLPPPSLPPAPALVPTPPAKDSKSSSSALHWLADLATQKEPKESLRSMMGRDSRSPFGLDSFSTLSKPSGSSPKLFNSLLLGAGPSQPKAEGTSLRDLLNSGSGKLPQGPTEGGVPFPPVFSTASQADKMKGGLPNFLDHIIASVVETKKSEVRRASGSAEVIESATAPRREGVMGLSVLDPHTSHSWLCDGRLLCLQDPSNPNNWKIFRECWKQGQPVLVSGIHRKLKEHLWRPEAFSEEFGDQDVDLVNCRNCAIISDVKVREFWDGFQVISKRLQGSDGQPMVLKLKDWPPGEDFRDMMPTRFNDLMDNLPLPEYTKRDGRLNLASRLPNFFVRPDLGPKMYNAYGLISTEDRKVGTTNLHLDVSDAVNVMVYVGIPEGENDQESEADLAGFKEVMQTIEEGDVDDMTKRRVYEIKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRRRLYEEYGVQGWSIVQFLGDAVFIPAGAPHQVHNLYSCIKAAEDFVSPEHVKHCFRLTQEFRHLSNTHTNHEDKLQVKNIIYHAVKDAVATLKAHEPKLGRS
The following text describes a protein:
Function:
Incorporates a polar amino acid serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVGAKAGPSPGTSLGLAQQHSGGSSVLVKSPFCQVCCCGPAPCASCCHSRWPSLTASTCSRLFYILLHVGASAICCLLLSRTVVERVWGKTHRIQMPSGLCAHLFGLSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVHLHSPTSPRAQLHNSFWLLKLLFLLGLCAIAFCIPDEHLFPAWHYIGICGGFAFILLQLVLITAFAHSWNKNWQTGAAQDCSWFLAVLLATLGFYSMAGVGAVLLFHYYTHPAGCLLNKMLLSLHLCFCGLISFLSIAPCIRLKQPRSGLLQASVISCYIMYLTFSALSSRPPERVILQGQNHTLCLPGLSKMEPQTPDISLAMLSASIMYACVLFACNEASYLAEVFGPLWIVKVYSYEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQHLSYNYSAFHFVFFLASLYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLLLAPLCWPPTQKPQPLILRRRRHRIISPDNKYPPV
The following text describes a protein:
Function:
Demethylates proteins that have been reversibly carboxymethylated.
Sequence:
MDSSNLTSLPEEGSEETHNLHSAFSSIPARLPSQTSSQKYAPLDWSDYFDREDDIQIPDSDDVFHVYMAGTEGPVVFCLHGGGYCGLSFALAASKLKEKARIVAMDLRGHGKSATQNDVDLSIKVLSKDTLCGDVFSVLKTMYGDAPPAIVLVGHSMGGAVAVDVAAKKSLPSLAGLVVVDVVEIEWSVKSGSLRNIDSARVSIPNTLKYDESKKCYTHRARLEETEQYWREWYEGLSEKFLSSPVPKILLLAGTDRLDRALTIGQMQGKFQMVVVRHTGHAIQEDVPDEFATLLLNFISHNRIGPHGIEIPGLRRPPRSKP
The following text describes a protein:
Function:
Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages (By similarity); Has very strong antibacterial activity against the marine Gram-negative bacteria V.alginolyticus (MIC=24 uM), V.fluvialis, V.harveyis (MIC=12 uM) and V.parahaemolyticus (MIC=6 uM). Has antibacterial activity against the Gram-negative bacteria A.hydrophila (MIC=6 uM), E.coli (MIC=24 uM), and E.coli BL21(DE3)plysS (MIC=6 uM), and the Gram-positive bacteria B.cereus (MIC=24 uM), B.subtilis (MIC=6 uM), C.glutamicum (MIC=3 uM), M.luteus (MIC=3 uM), M.lysodeikticus, S.aureus (MIC=6 uM) and S.epidermis (MIC=12 uM). Possesses antifungal activity against A.niger (MIC=24 uM), F.graminearum (MIC24 uM) and F.solani (MIC=24 uM), but lacks antifungal activity against the yeasts P.pastoris GS115 and C.albicans.
Subcellular Localization:
Secreted.
Sequence:
MKTFSVAVAVAVVLAFICLQESSAVPANEEQELEQQIYFADPEMPVESCKMPYYMRENRQGSPARCRFCCRCCPRMRGCGICCRF
The following text describes a protein:
Function:
Potentially involved in chemo- or phototactic signal transduction.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSIRSFAHRILRRALPGFVRRSYLAKFGVALLAVVVCISAAGGVMYLNTSEHLQQSSRTELKKAAELSSSAVDNWHDERTNNARMLAQYGVFDNDNATEVQQFFTDEQHHLPSDVRDIHYVSLTDARVITSTDAGLRNASFGSEAAPWSRQQLTPGDDGVFVSQPYVNDGITEVAYVARVSSTPGRRTAVVMTASLAAISSSFWDPTPHSFTQLVDGTGSVIADDSKRATRQPYVENATSPIVGARAVGFQPAAQAAKEMDQAHETAYAPVDGTPWVVTLHVPTSEAYGLASNMAENVLLILGIALAGLVFIALTLGRGTVRALNDLEAKAAALERGEYDTDLDVARVDELGRLFEAFASLRDTVQARIRDANEQQVDAEAARSEAEAAQADAEAAQAEAEAAREESEAQARRLETTAEAFSETMRAYAAGDLTVRLDADVEQAAMADIAAAFNEMAADMEATIADVVAFADEVATASTDASDSAAAVEQTGRDVSDAVGRIRDRAADQRDQLEAVASETDEMSATIEEVAASADQVAETSQRAAALGDDGQAAAQDAVAQLEEIEDETQAAATAVDDLEAKMSEIETIVAAITDIAEQTNMLALNANIEAARADQDGDGFAVVADEVKDLADESKASAAEIEALVAEVRAQTETSVAAMDRIQERVSDGVETVSETERSLSEIAGRIAEADTGVQEISNAMDDQAASVSDVTTAVGDVAALGEETATEAESTADAAAEQATTLSDVAAQTETLAEHAVALREHAAQFEVAADNEPGA
The following text describes a protein:
Function:
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MFSKDINECEDPNKIFCHEIALCTNVPGSYSCTCPTSYHGDGKKQGTGCIRAGISVVSLILIATGLRLYRGLKEREKKKIKQKFFKKNGGLLLQQQISSSKESVEKTKLYSVEELERATDGFNSSRVIGKGGLGTVYKGMLSDGSIVAIKKSNTVDEKQLDQFVNEVFILSQINHRHIVRLLGCCLETEVPLLVYEYVSNGTLFHHLHDEGHASTLSWKDRLRIGSEIAGALAYLHSYASIAICHRDIKSRNILLDENLRAVVSDFGLSRSIPLDKTHLTALVQGTFGYLDPDYFHSGQFTDKSDVYAFGVVLAELLTGEQAISSDRSEQGLANHFRSAMKQNRLFDILDNQVVNEGQKEEIFAVAKLTKRCLKLNGKKSTTYETGCASLCPDNNITVGFSSSACTGIGCCRTDLQTDMTWFYLRIRSINMLTPAWNYEPCSLAFIAERNFSISENFDLSSKFDRNLYFVPAILDWSVGNGQGYKCNCSEGYQGNAYLANGCQDINECEDPNKIFCHEIALCTNVPGSYSCTCPTGYHGDGKKQGTGCIRGKHKHLLALVFSLGAGISVVSLILIATGLRLYRGLKEREKKKIKQKFFKKNGGLLLQQQISSSKESVEKTKLYSVEELERATDGFNSSRVIGKGGLGTVYKGMLSDGSIVAIKKSNTVDEKQLDQFVNEVFILSQINHRHIVRLLGCCLETEGHASTLSWKDRLRIGSEIAGALAYLHSYASIAICHRDIKSRNILLHATYKLRINDIAYRSCFNNQSGKTDSSYVSYNRTHHFSYSFTHNKFIAIGCDIFAYITGHNSTAYATGCASLCNTGNDITAGFSSSACSGIGCCRTYLQTDIASFYLRIRSINMITPTWSSEPCGLAFIAERNFSIREHFNLSSKFDKNLYFVPAVLDWSVGEVSCHEAIRRKNYACGQNTYCNNSIQGRGYNCHCLNGYQGNPYLANGCQDINECNDPKQNACHKIAICSNIPGSYSCTCPAGYHGDGKTNGTGCIPGKRKHLLALVFSLGVGITVVPLILIATGLWLYRRLKEREKKKIKQEFFKKNGGLLLQQQISSSKESVEKTKLSEQGLANHFRSAMKQNRLFEILDNQVVNEGQKEEIFAVAKLAKRCLKLNGKKRPTMKQIDIDLQQLGRFQEQLSFQKTKIQEPSLQQQTCQDYFTVTGSMFIYAIDFWNNDVMNGSELCFTFFNLFQYGTHIIRVQLGLRLLDNQSRSTFIYTSSSFSKPNNSIQSKLPKLFFFKS
The following text describes a protein:
Function:
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
Subcellular Localization:
Nucleus.
Sequence:
MNLRQESMMGKRKLASEGKGNSVDEEVTWEQMVMDSAAAVAAFNGARRARKRFVGVRQRPSGRWVAEIKDTIQKIRVWLGTYDTAEEAARAYDEAAYLLRGANTRTNFWPFSPSSKPVLPSKIVNLLLLRLKDSSASAAASMASNSPVNVLGYEAAAGEDMCIDDFFNVPEDCSQNTISSSSTSTTTTSSSATATDCMLEMMTFGLNFANTENGDHDLKAIHLGNSHIEGGREEKREGSKEEEEIDMEGLLDFQFVDAVGLSCCCSPFEIAEEMVEEPMEQQENDGDDPSMLRETMKRMKYERKFSASLYAFHGIPECLRMKHNESAGNDKPEHQSNLRNNFDTDKKPEIKEEHEQVGIIPETSIETGSPSAYSSLSNEAAEIWSSLDLPPIGLVS
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite.
Sequence:
MKKKQTTKALLVTCITDHKQDFYRLAFSYVKNQDDALDIVQESIKKALSSVETVRNPETIKSWFYKILVRTAIDFLRKQKKIRVMDDETIEFLSKGKEDHYKDTDLHEALDELPYRYKTIIILRFFEDLKLEEIAEITGENTNTVKTRLYRALKLMRIQLTKEDLS
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEAEATVIKVTCPEKQEELPKASSEIRDEPVAASLQNDDKKTPVSDYASQRTSESLVGVLSIPVIVQSGDASIQQATSDQVESRNGEQSEGTTCIAQGNNELTDGNSASGHGSSVISETLIEAALSSESLPCQPKQDALKDRGGTVKCAGCGKAFSQPWALPQRANRVVLSLCDDCENITSAMFICISCGQECSSLASLRAHKQTHLVPEQRIFVCEMCGVGFQKQISLEVHTCAGLVNVISKSDGKGATLQEADVPQKQARSRRKPRVTQKVRVEAIVKTLSKRNQQTARSVPASNNVSPKKAQSAKRSTSARKPQARGRKKTIRKTPSAVLPTKATPLKKKLVVNFSPPSSRPRTQRKILKIPKVFECKECSEFFTESKELRKHKAIHKKTRETFHCETCKKEFKSKGNLSRHELTHSEKPTTVCEICDKVFQSIHTLLTHKKTVHNELKPFVCDICHKDFKQLGNMKTHRRTHTGEKPFVCQECGRAFAQMGNLQAHMVIHAASKPHVCEMCGKAFSYLRSLQNHVRGTHTGERPFACPVCGKTFSNPSVLRDHKRTHSDKRGYLCDKCGKGFKSYKNLKQHEKFHLDVRPYSCQVCGKGFVWFKSFQLHKRTHTGEKPYTCDQCDKAFSNINSLKNHKQKHLSGYAAPPPKSRSTAKTHPPPISAPPPSLPPLQSQTMIIPHPHPSLHQGHTRDHMVNSIHHHADVPSSTSSSTPPIHHPTISSHSQAYSHVVFPQAFPSFVTNPSGDFTIL
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for segmental identity of the second through eighth abdominal segments. Once a pattern of abd-A expression is turned on in a given parasegment, it remains on the more posterior parasegment, so that the complex pattern of expression is built up in the successive parasegments. Appears to repress expression of Ubx whenever they appear in the same cell, but abd-A is repressed by Abd-B only in the eight and ninth abdominal segments.
Subcellular Localization:
Nucleus.
Sequence:
MSKFVFDSMLPKYPQFQPFISSHHLTTTPPNSSSAAVAAALAAAAASASASVSASSSSNNNSSNTIAGSNTSNTNNSSSSPSSSSNNNSNLNLSGGSLSPSHLSQHLGQSPHSPVSSSSPFQQHHPQVQQQHLNHQQQQHLHHQQQQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHGHAHQQLLLTPPSAGNSQAGDSSCSPSPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEKMKAQETMKSAQQNKQVQQQQQQQQQQQQQQQQQHQQQQQQPQDHHSIIAHNPGHLHHSVVGQNDLKLGLGMGVGVGVGGIGPGIGGGLGGNLGMMSALDKSNHDLLKAVSKVNS
The following text describes a protein:
Function:
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
Sequence:
MSVDAATVRRIAHLARIAVSEGEVPHLQGELNAMLAFVEQLSEVNVEGVEAMTSVTPMQMKKRQDVVNDGEIADDIVANAPATEGHFFLVPKVVE
The following text describes a protein:
Function:
Plays a role in endocytosis and trafficking to the vacuole. Functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress.
Sequence:
MAEVDIAPQFGLELKDGFKATNTWVSNGIDWLDDIQAFYRERSVIEKEYSAKLNALAKKYYEKKTKKSSNLSVGDTPAMTPGSLERLGIFLTELVVQLLTNLIACSASLTTWTTQLTTLESRAAEHDRFGGELITQVAEPLKVLGGRYDELRKRHVEYADKLEKERDSTYADLRKMKGKYDAACQEVENKRKKAESSFDYSKTKAQNAYQQQILEMHNVKNSYLIAINVTNKQKEKYYHEYIPDLLDSLQDLFESRTVKLNGIWTLAAQLEKGMLERSTEFTNHLLTEIPRNQPSLDCMMFVRHNVGPWQEPPDKPFEPSPVWHDDNAMMVGDTAKVFLRNVLSKSKNQLGDLRREVDKKRREVESIKRVKQQIREGKDKRDEVEVVRAIFALQEELHQVDHKRLTAEVETSTITAAVGDVTLGSKSHNFKSQTFKIPTNCDLCGERIWGLSAKGFDCRDCGYTCHSKCEMKVPAECPGEQTKDEKKKLKAERQEAANALKAPGTGLADSVAELPTMSRSNTMNSLSSGYAASANRSLSAKSTTEDTPSDTTVDRRQSVSSSLKPGILKKNRVVAPPPAAYISELPGSGVINGSASNEQKGKMLYAYDANGSEEVTVAEGSEVIILEPDDGGWTKIKYGSKEGLVPTAYLEILPPSSHNSTNRPVSIISTSGSSISASKKQGPAVAPKRGAKKLKYVEALYEYTAQSEAEHSMVEGERFVLIKEDPGDGWAEVEKGGHVKSVPANYVQIV
The following text describes a protein:
Function:
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
Subcellular Localization:
Cytoplasm.
Sequence:
MGINLLPIEMDEIRKRLGREPNETEWRVIDAVWSEHCSYKSSKIFLKSFSIDSPNVIMGIKDWQDAGAVDIGDGWAVVIKVESHNHPSAIDPFNGAATGVGGIIRDIISKGAKPIALMDMIRVGNLKIKKNVWLLKNIIAGIAAYGNSIGVPVVGGELSFDDTYNDNPLVDVAAIGIVRKDKIKPSIVDKAGLKLVLAGLTGVDGLGGASFASRKLSGEDEIGAVQIADPFAGKIILDVTLEIADKVEAIKDLGGGGLAVAVTEITNGLGATVDIEKIPLRVKNMNPSDVIISETQERMLYAVEEKNVKEVCEAFEEYEYPCSVIGEITNEPVIKFRYIGKDLVSLPTNVLLNPPRFLWPIKNTKKNVEEKIVDLPLESAIYTVLTHPDLVSKGWAYSQFDYEVNTSTVVKPGDADSAVVSLPNGKLLAIKADANPDMCAEDGYECGKGIVAEAYRNLATVGARGMVAVDHLQFGDPKKAEVYYTFVEAIRGIGEATRFFNIPIVGGKVSFYNENNQGRPIKPTPLIVMAGLVQDKLLKNRVEDNLYVVSVGYTRKELGGSLLSKIFKIPSQAPKVRLQEDLLSSEVVIDSINEGKITFAKDVSRGGLAASLFSILVHGYGVEISTKSILSDTDNVIENLFSESSGRFIVLTNEPEWIVEKSKSKGIVASIIGRVNKKTNILTIDNIDYNLKNIVDNYFNFLEEVMGNG
The following text describes a protein:
Function:
Displays c-di-GMP-specific phosphodiesterase (PDE) activity. Seems to play a specific role in nitric oxide (NO)-induced biofilm dispersion. Enhanced NbdA synthesis in the presence of NO increases PDE activity, leading to reduced cellular c-di-GMP levels and biofilm dispersion. Does not show diguanylate cyclase (DGC) activity.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Domain:
The N-terminal MHYT domain might sense NO through a bound metal ion.
Sequence:
MPFLPGKMPKPAVCRRPATSFHADLAGGSRYLYWKHNATPSPHPRRPRVFRVQGDTAMDWQGLRFLGESPVDGYVLQNCTYSPSLVALAFLVACLAGYTALDMVERVGNSLSHPRLWQWIGAFCLGSGIWATHFVAMLAFHAPIALRYDLPITGLSLLIAVAASYLTMYMTARPRFGLLPCLLAACCIGLGIAAMHYTGMAAMRSVATQYYQPSLFALSVLIAIGAAFTALAAVPYLRGRRSARYRYMKLIASLLLAGAIAAMHFTGMAALVLSVPAGTPLELQASADSLRLGWLTGVLASAIAACGIWAAWSEKQRERRLSENSRVNALLNQLDHAHASLRQMARYDSLTGLQNRTAFNEVFVQHLENCRLRGKGLAVMFLDLDHFKRINDSLGHDSGDQLLKIVSERIRSVLRDSDVVARFAGDEFCVLADLTQDHEAHILSQRLMQKMKEPIALDGRTLVMTASVGVSLYPNDGEQCEELLKNAGLALHQSKACGRNNAQFFSRQLLVRATQELQMEEELRQALRDDQLELHYQPILALADGEVHQLEALVRWRHPTQGLLGPDRFIGLAEANGMIDQLDDWVLRRACRDLRSLHLAGHERLRVAVNCCASNLGRASLVDEVRHALEQAGLAACFLELEVTEDALMYNIDQTIPLLERLRELGVSLSIDDFGTGYSSLAYLRRLPLDALKVDRSFIMDIPASQRDMEIAQAIIAMAQKLHLKVVAEGVETPQQLAFLRENHCELVQGYLFSRPLPLAALEEFLRAYRFDAAPPLRSLNQA
The following text describes a protein:
Function:
Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEELKAYRPKTSPELDPSTLSNYTCFTVKLTTLHFDIDFEKKIVSGKVKYDLLNKSETDHVDLDTSYLDITKVSIQNESCDNQYKLHSRKEPLGSKLHILIPASTPKNFQLEIEFSTTSKCTALQFLDKEATDGKNHPYLFCQCQAIHARSLFPSFDTPGIKSPYKFSAKSPLKTLLSGLLIKEDNENNTVYFEQPVPIPSYLVSIALGDIARTSIGPRSDVMTEPVNLAKCKWEFERDMENFIQVAEKLIFEYEWQKFDSLVLPASFPYGGMEIPNLCQLTPTLICGDRSLVNVVAHELAHSWSGNLVTNCSWEHFWLNEGWTVYLERRILEALAVIEAKQQGKGDKEAHYYGEQVRQFNAIIGWTDLENDLKSMGDNVDKYSILVQDLKGKKNPDDPDDAFSTVPYEKGFNLLYLIEKIVGKEKFDLFIPAYFREFRFKSLDTFQFIDYLFDFFKEDAVKLDQIEWKKWLYEPGMPPIDPKFDTTLAQACYDLAKKCYQYALSEDDENEFTQFKLVANEINDFSPSQNIVFLDTLIAYEKVAGFSWKQHKKTLNRMATLYHDQYTETLNAEIKFRWFYLQATGEVLDFEVAMGEFLGTIGRMKFVRPGYALLNKVNRELAVRYFQRFENRYHPICKAMVRKDLQLD
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MGELAPVRGAVEAAGPAETRPCRGLELRAGAGSEAVTVLFDDVALYFSEEEWEILEKWQKEMYQQVMKTNYETLDSLGWVFSKPDLITWMEQGRMLFTRDQGHLEKTRITLSPSADEWLDLKNTGKLPRVGDQGTLKAEEEECHLNGLQKQGSCATLSGEERKILSNQRVALQHPSLPETEIVNKNLDVTASNQDKNDPWYKPMGTPGHLELPPGPRLYSCFVCRKVFHVKRDLVKHKRNHSNSQPCKYAKYKNQSRGHSGLRWTRTILCKRKRFQCTKCEKSYSFKCSLLIHQVVHTGQRPFQCSECDKTFQYKATLKKHLCLHKGERPFSCKECGRGFIQQYKLTEHLRVHTGEKPFQCPECDRSFRLQRSLKAHLCQHSGKKPFHCPECGRSFSRKTALQVHQRIHSGEKPFSCDECGRKFTRKTKLTEHIRVHTGEKPFQCPECDKNFRLKKSLKAHLFQHSGKKPFQCPECDKSFSWKNAMKAHQRLHNEEKPFACAECGKRFTQPSKLARHGRVHNRQKEFSCGQCEKTFPRQSRLTEHLRVHTKERPFSCAECGRSFSRHSHLTEHMRLHGEEEPFQCPECDKSFFWKASMKLHQRTHRGEKPFECSECSKTYTHQSQLTEHMRIHSGEKPFQCPECSKSFRLKGNLKSHLLQHSGKKPFSCVWCGKSFTQQYRLTEHIRVHSGEKPFQCPECDKSYCIRGSLKAHLHTHSGDKPFRCPECGKGFLQKRSLKTHLHHHREERPFSCDECGRSFTYLGALNTHIAVHAREKPFSL
The following text describes a protein:
Function:
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
Sequence:
MLRLQSLGSLPAHAEPAWTVSFNPTRSLLASCSTDRTIRLYSYIIPSSSDGLPSQDDSQAVFSLAKVIETDHKRTVRSIAWSPDGRTLASGSFDSTVGVWEEVIPLSDDEEEEDEGAQGVYKPAGVDSDGDGDGGKEKEWECVTTLEGHESECKSVGFSSDGALLASCSRDKSVWVWEVQPDADFECIAVMMEHSQDVKSIAWHPHEEILASASYDSYIHLAYDDPDSDWCIFQKLHPSLPSTPLTIPSTSPSHLIDALVPTEEEKKAEAELQVPPLEEDETVWCLAWSPDGRWLASGGDNGGIRLWQRTGSQPDSAFKEILHTAAHSRSVFSLSWSPPYPSAESAGSTDSTDLGMLASAGEDGKIIIWQITVPPSPSSASQEIDNEQISIRPIAAQKDAHGVNDINSVAWCVREDKKGWGMLSSAGDDGSVKVWRVVRD
The following text describes a protein:
Function:
Candidate tumor suppressor.
Sequence:
MTMNVLEAGKWKSIVPAPGEGLLAVLHMMVFTDALHRERSVKWQAGVCYNGGKDFAVSLARPKAAEGIAD
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins.
Miscellaneous:
MISCELLANEOUS: Present with 4824 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MNVTPLDELQWKSPEWIQVFGLRTENVLDYFAESPFFDKTSNNQVIKMQRQFSQLNDPNAAVNMTQNIMTLPDGKNGNLEEEFAYVDPARRQILFKYPMYMQLEEELMKLDGTEYVLSSVREPDFWVIRKQRRTNNSGVGSAKGPEIIPLQDYYIIGANIYQSPTIFKIVQSRLMSTSYHLNSTLESLYDLIEFQPSQGVHYKVPTDTSTTATAATNGNNAGGGSNKSSVRPTGGANMATVPSTTNVNMTVNTMGTGGQTIDNGTGRTGNGNMGITTEMLDKLMVTSIRSTPNYI
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MARGTMRLLALLGTLLLVASWSGLDVDAKKSRRAKDVALKGGEKLVQLQDRVRDGVIPFTNELFGRYAVRPDRPYHLVLLFTATAAKYKCETCAQVAPEFSTLGESYEAAKQLKVDTRDGLDVFFGVVDFEANQEAFGMYEFTSAPHVVYVAPDRSQDAGERMPKKTKVDPQNLYNVYSQGKEAEAMATFVKHRTGFEFAIQRSKTYLYVLLVAALASTGVTAKLVLAHLDVVLAKLCRKQLWMTVSLLFYGLSVSGMVYCIIRNPPPYSADRKGNIQYFHPQGRQQFVYEGLIVGGYDVAAAICMILLSQWALYVRNPTVRYVAIVGCALGFVFMYRQMTDAYKFKNRWYTGWMGF