lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Probably responsible for the translocation of the substrate across the membrane (Probable).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MIKRNLPLMITIGVFVLGYLYCLTQFPGFASTRVICNILTDNAFLGIIAVGMTFVILSGGIDLSVGSVIAFTGVFLAKVIGDFGLSPLLAFPLVLVMGCAFGAFMGLLIDALKIPAFIITLAGMFFLRGVSYLVSEESIPINHPIYDTLSSLAWKIPGGGRLSAMGLLMLAVVVIGIFLAHRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLSTGLATLAGIVFSIYTQAGYALAGVGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQGLIQTYINFDGTLSSWWTKIAIGILLFIFIALQRGLTVLWENRQSSPVTRVNIAQQ
The following text describes a protein:
Function:
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MARYGWTSYDTREGGTQTIEDVQNKIDITTEFIKKSEGSSAGNWALRIRGTPRKDAPADLKTTVVFYVGMESFDTCTKCKLESSEQVGAEEDTSIHAVNLWMEHPQLGTASMHIPASVGENGRHEAMIVKSMNVSEDKLWRANTTFLDALKDQMKDKKEDAAMDPMLHNEIGNGNMHFVQMNCHGKFESFGKTFVHVFNPKTPFRDEQHLEFAEYVLSNLLGGLGYFAGTNQVDTSKKAIYAETTGKFWEKSAEAKSHATPEIRGPYELLTHTPSRAMFPRGFLWDEGYHLLPVLEWDADLAIEVVRNWLALMDDDGWIAREQILGVEAEFATPADFITQFPHIANPPTMFLVISKLIDMLGSKTKYYGHESWYLTKADAGKTFIVDVYPLLKRHYEWYRKSQSGDVEAHSVPSANLNEGYRWRGRTPETNFASGLDDYPRAEPPDITELHVDALCWVGAMARVLEKIADYLNQTDSLPYQTHLRGVQTNLDALHWDDKQSIYCDAVVRDSAHSLVCHKGYISLFPFMTGFVGASHPHLPATLDLLRDSAHLWTDHGIRSLSPESPKYGVGDNYWRSPIWVNMNFMILEQLLVLARTAGPEQQRCRDIYVELRANIVHTVYSAWLQTGYIWEQYDPVGGHGQRTQHFTGWSALVVQIMAMPDLAGAEGYKERVKGYYEEAKKTAVQNRKSSTGLVVGVGMLVVFVYVTRRRFMGTWRGLKRKHRRVSSNE
The following text describes a protein:
Function:
Functions as a two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Domain:
Histidine-containing phosphotransfer domain (HPt) contains an active histidine that mediates the phosphotransfer.
Sequence:
MALPILKGLLRGYVQSLFNEGIVNNHFSQIQTLKSDADPDCAVRLINIYLLDVERMLSELTCLSDLPDVDFSKLATLARSIEEKSSLVGAEHVRSACADLIQACERMQKQNFLRALGWIKNEFAHTRNKLDSFVQMERRIFRVEGREVK
The following text describes a protein:
Function:
Highly selective calcium channel localized to the inner mitochondrial membrane, which mediates calcium uptake into the mitochondrial matrix. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates ATP production, cytoplasmic calcium signals and activation of cell death pathways. Sufficient to operate as a pore-forming channel without the need of calcium-sensor or auxiliary subunit.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Domain:
The selectivity filter, in which calcium ions are arranged in single file, is composed of two acidic rings separated by one helical turn along the central axis of the channel pore.
Sequence:
MGHVLGGTLLAANRLARPPAVVLGKPRVCCWRASPWPVIVSSALQFSSSSARHTNYTSARYEARGRSTTQRKVDDRPWHRESSGSLPKSTSPDPTGGDATKGRLLTTPTRLLKLILPIPFHPEQEYINSDETKTNKPKEDAVEPLALLVHPQQPLSYLERLIQAEIPPLLVKDREKLPEIIFRAEADYTGGNKSNDGRREESNGNGSNVASYSGLGREGPSKGDTHWVRWSGSTEIGDFIRDAARGREFSVTIEGHAEELRVAVPSFKDRTYYMRMRLRRMSQEIDQMATVKRECDLLAHKGAHALAKGGFAALAAWWGIVYYVTFHTDMGWDLVEPITYLAGLASIMGGYLWFLFISRDLSYKAAMNVTVSRRQNALYQERGFDPAKWDQLVHDANGLRREIKFAATEYGVEWDEMKDLGGEEVKEVLEEEKGGKARKREQEDEDGDGDDDHDHDHDHVSHGAELQGQDILHANEAAANVPGD
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MQSRKFRDPPKVTGLSPKEGPPGTKLTIRGENLGFNEKDVFCIIVCGVNITLLAEWISPSKIICRTTNCKGPGDVIVSTKSGGIGTSTVKFRGLQILPNPLQDSAIWVDESSLFDRRLNSISRPSSPLQSGREDPLGLPMEHAPQLSDEEAHQMFPKGSSNLAHRNFEPALFLIESHSNTSFVDLRKGLEHLKRQSSGLKTEGPQTFIKSNLGTFMNCQDILATIHGDLCRHENIGDRVKATPGEESNEVDGGDEGKEADEMELKGEGDGSQDKMATLQKIEDLLLKGNENAQKIFQSVLHRKDRADSTRNALNVLNRFKFLFHLPITIERNIKKGDYEVVINDYERARQLFSKTQVTTFKKVYDEVENKIRELQVQLHEKLMELPTPLDEQKRLIRYLVELGGPGDPAWECIVNEHKWIQDILAGCKDQHIQIDQKGCEVIEPPSHASKVRGHRRNFSGSGIQVKFTSDSNMDGKFSPPQQVLFLEELADNLLTTFPNLWRLGQSYFNASVVSEAGGKSMIVDSTKEASFTAMMTKITTYFADLVRAAFLPESLEKKNEKDRAKLGEWGASKNEVGAGAWLPQCVRSIRSVLSTLVNLEVPTPLLEVLQSLLADLRVHCMVTLFKEATEDIKALHGRETWVLQMDEHGGITTTPTLFESIVVDILQHLKEVIICTSSTEKKIFDNRHVERQTVDLASDLLMAFASCLEQLAFVGDDGDTQKLRLSEAAMRTPESLFQSPEDSIPSMEQCLVIVLSNCSHVSQHVVPNLIEQFKRLGYPSTHEIENISQEAYAELDEKIFEAYCEQKIDPLVGALEVGVYAGNYDWGDCPEPTGASPYVKEALMNAVAIHAEINAIAPAFMLRVMGRVLEAVADEMSRIMSCVTGAFCSSGAVQARLDIGMLEVAMSPYRNAGTSASFKEALSVVPQLKTELHKKLLQELQSSFHRDLQFLLTCFTTDS
The following text describes a protein:
Function:
Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins; Probable hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
Sequence:
MIAFVEEVSSSLVREFLSRKGLKKTIACMDEEHPRTATSINNRSLLRQVLNIEDLYRRNKVQNPPLKTVLEIIVKHHMEQQKKVKIMTGDGETARTVTPPAFTAGSPLICDTEENSSRSEIKATHSSPSTFLSLLSDENKSSGHDQKDVSAYDSERQKCQPLTSLQQEWESSAQKEPEKKSEAISRSRTNRNRRGMMSGPIPREMGRKKPSPRYDAAQPLFRRDGENQHSDDAHLDINTHSCAGRKPGLQRSPESLQSENNNRGNKAKAVNKNHMPNNSDLNVSDLVLDDVDDEDLQEISQVSVQRSVSECLPKSRPIDQSIAMDLKAVLLGSSLNCFSAEWRNQGLTFSDTHDLRYGIVQRKGGPCGVLASIQAFILKKLLFENTESSDSDLQRLRPSNATRRKCLVLALAEVLWKAGEEERATVAVNTGLNHFTPSGRYRSEGVLEKMVLFTVDNLRDLQILVEQHIEQFETGTLGCILLTISAVLSRSIEKVKEDMDVSSSTLIGAHGYCTQELVSLLLCGRAVSNVFDDDMELDSGGGDTTLLKGIKSRCDVGLLSLFEHYNICKVGAHLKTPSYPIWVVCSESHFSVLFGLQRELLTSKDQHLEFDLYYYDGLANQQEEIRLTVTVGKWRRSFQEVDSDSIPPLELCIRTRWKDVEINWNDTEPIL
The following text describes a protein:
Function:
Catalyzes the conversion of precorrin-2 into siroheme. This reaction consist of the NAD-dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme.
Sequence:
MVKSLQLAHQLKDKKILLIGGGEVGLTRLYKLIPTGCKLTLVSPDLHKSIIPKFGKFIQNEDQPDYREDAKRFINPNWDPTKNEIYEYIRSDFKDEYLDLEDENDAWYIIMTCIPDHPESARIYHLCKERFGKQQLVNVADKPDLCDFYFGANLEIGDRLQILISTNGLSPRFGALVRDEIRNLFTQMGDLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNIDVKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
The following text describes a protein:
Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MQEAQQTQSKSLFEVLGLNSSERDENHLLARRVVVVGDALSGKRTLVSRLFAAAVQQFPSSCVLLLSPIADGSENFSPYSQTTTDLNEGTRGNRDSSCGISVKPSGIVSPSCPPYDAAASSRSKAEIDGKRAPHFPHGVGIAHSFIFQRLPAGRASLVGSMDDCSSNTSGNSGGPSMFSATGSAAHSILTEYFCCDAPGALATALPTVLTLETSVVLVVVDGSSPWTLHEQIRRWYGHLKGHVAQLLRGELPKQDEVKRVRMTEQQKNFWATQEQVLGLLRNAWCEREGGVAKELVPPSSVVGDVCPLRTLIVCSKTDELEKLSRELEKSVRVSGEAVGGDTSLDADTPLRRTENQTSSPQTQAPWVTESLRSALCTGGLTLLQLVGQLLRKEAIERRSGLVGTGSSVNTTTTATSSSSVEQPQHCCKQEFLLPTSKAITTKGRVEATTGLNADGSPLAATLAGSYSTFVHPFYKSLWSFLFQVLYEFQTLHNRIGSTSALDAQSRRASQFTDSDCSDRAVRKPLVLAGDIDWHISALFHPYTFLPHGVDHVSLLNPLVASTEAINLQNIFGELGEEGVGCCGDITERRSCDESVPLRGDYMRKIETLLAANTVSTERTA
The following text describes a protein:
Function:
Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.
Subcellular Localization:
Secreted.
Sequence:
MALSTRTQAACLLLLLLASLSSTTYLHQQMRQTTELQPLHGEESRADIAIPMQKRRKRDTNFPICIFCCKCCNNSQCGICCKT
The following text describes a protein:
Function:
May influence gene expression by regulating the function of the PRC2 complex and modulating H3K27me3 level.
Subcellular Localization:
Nucleus.
Sequence:
MSTEPEGVESDSNADFAINASSFDYGMAHTSETLADPMSFQAQDLVVNLTGVERKVFVSARDDKDSLCNGVDFDADSDLLKNKDKKGFSKENLKLFDSDLVWAKLRSYPWWPGLVFDKSVASKAAMRHFKKGNVLVAYFGDCTFAWNNASQIKPFHQNFSQMQEQSNSAEFRDAIDCALDEVSRRVEFGLSCSCVSEEAYNKLKTQNIINAGIREDSSVRYGGDKLSDGISFEPAKLVDYMKHLACFPCYDATEKLQFVINRAQVLAFQQWKDYSHFIDYETFVRSVESAATLASLPEVNMDEGISAKKRKTDYKDNAEQTKEKTLSDLTVKKRCGSRSTEKLDGKSHSEKKRKVESSESGKSEKRIKKSQQKEDSVSKHSNEESLLSVGDTNKLQKTAEPCHGTGVENEMNSLTPTLKPCRASKSTEVENEKTKKPRHQELAERKISSPDEMLSSLHAANTSTGIPDSINIDPSNYEDFEKFINELFCSKLNGDSKKASITETSEPCDKKDSAEEEILPANKEITGSGSKEQIGLKDCSADSLPPYALVLNFADSGSVPSEEKLNEIFKRYGPLHESKTKVTMKGKRAKVVFKRGEDAKTAFSSAGKYSIFGPSLLSYRLEYVCPKRKKTT
The following text describes a protein:
Function:
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form.
Subcellular Localization:
Cell membrane. Cytoplasm. Nucleus, nucleolus.
Sequence:
MGNGISDQPNFLSSLPFCNSLHIAILGLDSAGKTTVLYRLQFNEFVNTVPTRGFNAEKVRIPVGDSRTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSLDAERMEEAKTELYKIARSTENQGVPVLIIANKQDMRQALPLSQIETMLALNELGPSTPWHLQPTCAIIGDGLKEGLERLHDMIVKRRKMLKQQKKKK
The following text describes a protein:
Function:
3'-> 5'-exoribonuclease involved in ribosome biogenesis in the processing of the 12S pre-rRNA. Displays a strong specificity for a 3'-end containing a free hydroxyl group.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSTLLLNLDFGEPPPKKALEGNAKHRNFVKKRRLLERRGFLSKKNQPPSKAPKLHSEPSKKGETPTVDGTWKTPSFPKKKTAASSNGSGQPLDKKAAVSWLTPAPSKKADSVAAKVDLLGEFQSALPKINSHPTRSQKKSSQKKSSKKNHPQKNAPQNSTQAHSENKCSGASQKLPRKMVAIDCEMVGTGPKGHVSSLARCSIVNYNGDVLYDEYILPPCHIVDYRTRWSGIRKQHMVNATPFKIARGQILKILTGKIVVGHAIHNDFKALQYFHPKSLTRDTSHIPPLNRKADCPENATMSLKHLTKKLLNRDIQVGKSGHSSVEDAQATMELYKLVEVEWEEHLARNPPTD
The following text describes a protein:
Function:
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
Sequence:
MSTPEPVLAGPGILLVLDGWGSADAADDNALSLARTPVLDELVAQHPSTLAEASGEAVGLLPGTVGNSEIGHMVIGAGRPLPYDSLLVQQAIDSGALRSHPRLDAVLNEVAATSGALHLIGLCSDGQIHAHVEHLSELLAAAATHQVERVFIHAITDGRDVADHTGEAYLTRVAELAAAAGTGQIATVIGRGYAMDKAGDLDLTERAVALVADGRGSPADSAHSAVHSSERGDEWVPASVLTEAGDARVADGDAVLWFNFRSDRIQQFADRLHEHLTASGRTVNMVSLAQYDTRTAIPALVKRADASGGLADELQEAGLRSVRIAETEKFEHVTYYINGRDATVRDGEEHVRITGEGKADYVAHPHMNLDRVTDAVVEAAGRVDVDLVIANLANIDVVGHTGNLAATVTACEATDAAVDQILQAARNSGRWVVAVGDHGNAERMTKQAPDGSVRPYGGHTTNPVPLVIVPNRTDTPAPTLPGTATLADVAPTILHLLGHKPGPAMTGRPLL
The following text describes a protein:
Function:
Catalyzes the oxidation of p-hydroxymandelate to p-hydroxybenzoylformate in the biosynthesis of L-(4-hydroxyphenyl)glycine and L-(3,5-dihydroxyphenyl)glycine, 2 non-proteinogenic amino acids occurring in the vancomycin group of antibiotics.
Sequence:
MTYVSLADLERAARDVLPGEIFDFLAGGSGTEASLVANRTALERVFVIPRMLRDLTDVTTEIDIFGRRAALPMAVAPVAYQRLFHPEGELAVARAARDAGVPYTICTLSSVSLEEIAAVGGRPWFQLYWLRDEKRSLDLVRRAEDAGCEAIVFTVDVPWMGRRLRDMRNGFALPEWVTAANFDAGTAAHRRTQGVSAVADHTAREFAPATWESVEAVRAHTDLPVVLKGILAVEDARRAVDAGAGGIVVSNHGGRQLDGAVPGIEMLGEIVAAVSGGCEVLVDGGIRSGGDVLKATALGASAVLVGRPVMWALAAAGQDGVRQLLELLAEEVRDAMGLAGCESVGAARRLNTKLGVV
The following text describes a protein:
Function:
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Sequence:
MGYAEIAIRPSGSGKKIQRQGGLSRRFSNVSYYGLTTPPYKLDALEPYMSKRTVELHWGKHHQDYMDGLNNQLATSPLYGYTLEDLIKEAYNNDNPLPEYNNTAQHAYYLDYKDDKLTYVTNFMDHLVSWHTVTLRMMRAESFVNLGEPNILEA
The following text describes a protein:
Function:
Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
Sequence:
MPDIKLLSEGIFEIMKDKRQLATLNLDPGKVVYGEKLISVEGAEYRTWDPRRSKLGAMVLKKFNIPLSKDSKVLYLGAASGTTVSHVSDIASEGAVYSVEFASRSMRDFIRLASRRKNIFPILADAGKPDSYAHIVEPVDLIFQDVAQPNQAEIAARNAARFLNKNGYLLLSIKARSIDTAASPKEIFKEEVKKLEQAFEPGFEILTARDLMPYHEDHLGVLAKLKE
The following text describes a protein:
Function:
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.
Sequence:
MGSSSSYASTFSLPSVSSAGTSPESPCSVGVYGKGVAAGPFASSSTSAAAAAAASIKYTRLTEFGSNQEWIGFIENNVFHQFVSIPRDADWSQLKESVIALLDLASDCLECTGMVLYLDRECTHFQSLLRDFMWVGFTPKTAGVISEKWVMLGMDL
The following text describes a protein:
Function:
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MERLTLTRTIGGPLLTATLLGKTTINDYQVIRMPFCHLSTYSLVWVMAAVVLCTAQVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGYWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDREP
The following text describes a protein:
Function:
Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription.
Subcellular Localization:
Plastid, chloroplast stroma, chloroplast nucleoid.
Sequence:
MASTLSFAASALCSPLAPSPSVSSKSATPFSVSFPRKIPSRIRAQDQRENSIDVVQQGQQKGNQGSSVEKRPQQRLTMDVSPFGLLDPLSPMRTMRQMLDTMDRMFEDTMPVSGRNRGGSGVSEIRAPWDIKEEEHEIKMRFDMPGLSKEDVKISVEDNVLVIKGEQKKEDSDDSWSGRSVSSYGTRLQLPDNCEKDKIKAELKNGVLFITIPKTKVERKVIDVQIQ
The following text describes a protein:
Function:
O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis. Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-decaprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoic acid. Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone. Also able to mediate the methylation of 3-demethylubiquinol-10 into ubiquinol-10.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MFTRNVMILPKMAHSMCQRFVSSNSSILAREIGHFDDLAKTWWDWDGSSRLLHLMNPPRIDFIRSIVKQKNWFPGKRILDVGCGAGILSESLARLGAHVVGLDASPGTIEAAQQHMKQDPSLQNKLRYKLGSIENTNFNGKQFDAVTVMEVVEHVAEPANFLNELMRHVKPLGYVFLSTISRTMVSRLLTLTLAENVLHIVPPGTHTYEKYIRPEEMREFFLEKGWAVNGERSVAFNPFLGKWVLGAPGTKVWCNYFFSAQKPAMRGK
The following text describes a protein:
Function:
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.
Subcellular Localization:
Cytoplasm.
Sequence:
MSIFAPVPDDPNSEEHDLLGISKLTESFSALTGAIDTRIDALVKETQDSINSQTEAYTEGEIAQCDETLEAMRRIMKQCDQIEQEFDKIAIIGEIAKDFQVRLAQAEKDLVELSQQ
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MDQTVLSSQVYPYTIQTQSECIIVNQIDGSSSGDGSKPVKRRRKRRSKGSSSATNEDDVRAMERMFRKRKLTDEQVIMLEYSFENEHKLESGRKEKIAGELGLDPRQVAVWFQNRRARWKNKKLEEEYAKLKSQHDSDVLGQCQLESQVIKLTEQLSEAQNEIRKLSELVVVQETSTNSSSSSFSIEANDAPTDFEFSPMDTINDNIPLYMLDNNYYLQNMEYWDGLYVQF
The following text describes a protein:
Function:
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
Subcellular Localization:
Cytoplasm.
Sequence:
MNYDHILIRFGEISTKGKNRKSFIERLKQNIRLVLKDYPNLKYFSNRDRMTITLNGEDPEALFPHLKQVFGIQSFSLAIKCDSRLDDIKATALKAIKDQYKPGDTFKVATKRAYKQFELDTNQMNAEIGGHILRNTEGLTVDVRNPDIPLRIEIREEATFLTIRDEKGAGGLPVGSAGKAMLMLSGGFDSPVAGFYAMKRGLSVEAVHFFSPPYTSERAKQKVMDLAKCLSRFGGSMTLHIVPFTKTQELIQKQIPENYTMTATRRLMLQIADRIREKRNGLAIITGESLGQVASQTLESMYAINAVTSTPILRPLIAMDKTEIIEKSREIGTYETSIQPFEDCCTIFTPPSPKTRPKKEKIEHFESFVDFEPYIQEAVDNIETMTLYSEQEANDKFAELF
The following text describes a protein:
Function:
Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
Subcellular Localization:
Nucleus.
Sequence:
MFQPAAKRGFTIESLVAKDGGTGGSPGSGGAGSHPLAVAASEEPLRPTALNYPHPSAAETAFVSGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGSSSLQPPHSFFSAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND
The following text describes a protein:
Function:
Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MRGRPLPLKMLNKHMWLIVVGLILILGFFMVFLQLSTSSDGNPMNRRYSSWSELGKALAHKNIPALHPNLEFYKPPKSHPEFMGQANLHVFEDWCGSSIQQLRRNLHFPLYPHVRTTVSKLAVTPQWTNYGLRIFGYLQPATEGEYQFAVSSDDNAEFWLSKDHTVEKLSLMCRVGPTGKQWTAPGEFGKFQDQVSITVRLSPTVKYYFELLHKQDNAGTDHVEVAWRLTELTSPFMVIDSRFLSLFSNDTGDSLGDTTQIPVSAASFHSEGLEQHPADMLKPDKRDHFYKVPLMTKNRIRNVLPTCSYKPSYLVEGYPLQRYQGLQFVHLTYVYPNDYTRLTHMEKDNQCIYQENMRRSNRFTYKRYMKMDQPEQKPNIQPGMFEDYNPSDFQYEEAQESENRGDVPRKNSLRQQRKLLSLISKREPGISERSRAGPHRRTESRHPQNWTESSVNIAVSVSDVQNKMAFNVQDKIIPDVDNASPTLTFSSQVHSQPDTRNSSQVRRPRAAQERHRDRRKQPGRRRLKDNKSNLGESAVGKAKMPQFTESTAKAITQNKIGNEQDQIYRNKQITQTTMPNKLKVELKTKYSWSYEPKQEWTKQPKVEMYEYRRGERAESRTEAKLDNARNLELNLNDGKIQNIATYKTGNPVPQPEKEEMQKPEPISVLQLGRFDPRVNRPDLQLQRVEEQNNEIAIPLPQQEEGQKPEFIDISRLGRFDPRVKRPDLEQVEEQKNIVDIPSDAVRPVNAQYDDDDDPQEEEEEEEDEEEDMEYPLIYEQSVNWNQTFDFGQTDFQIIRPDSIDLQCNTSGNLLLREREVVGVVAAFMRKLNQKFRGMYHLLNIINVEKRRDYLHGSRYFLELELKDRYGHIQRFAHYVYAPKWQGIFSLDDEQERAMKNMMWGSYRRLLGANFEPDLCWPSGLNWNPQATVHFIVPIKNQARWVQKFIRDMETLYLATLDSRFNVIIVDFNSTDFDVEAALRQSHVPSYQYVKLQGSFERSAGLQAGIDLVKNPHSILFLCDLHMHFPPSIIDSMRTHCVEGKMVFAPMVIRLDCGATPRWPEGYWEVNGFGLLGIYKSDLDHIGGMNTQEFKERWGGEDWELLDRIIQAGLEVERVAMRNFYHHYHSKRGMWNRRQAPNWR
The following text describes a protein:
Function:
Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. Involved in the regulation of the ethylene-mediated signaling pathway. Involved in salt stress responses. Reduced cotyledons size and early flowering.
Subcellular Localization:
Nucleus. Cytoplasm, cytosol.
Sequence:
MEGFLTDQQREMMKVATQTADDLPPSQKPHSVLLEHLPKPSGGGKASGASNAVKHRRSHAGRSIRSKKDGGGGKGNWGKLIDTDGDYHIDPNDPNYDSGEEPFELVGATLSDPLDDYKKAAASIINEYFSTGDVDVAAADLIELGSSEYHPYFIKRLVSVAMDRHDKEKEMASVLLSALYADVINPNQIRDGFVLLLESADDFVVDIPDAVNVLALFLARAVVDDILPPAFLPRAAKALPITSKGYQVVQTAEKSYLSAAHHAELVERRWGGQTRTTVEEVKKKIADILNEYVETGETYEACRCVRELGVSFFHHEVVKRALVTALENHAAEAPVLKLLNEAASENLISSSQMVKGFSRLRESLDDLALDIPSARTKFGLIVPKAVSGGWLDASFGYPSGECGRQQNEDEKLKRFKEDIVTIIHEYFNSDDIPELIRSLEDLGAPEYNPIFLKKLITLALDRKNHEKEMASVLLSSLHIEMFTTEDVADGFVMLLESAEDTALDILDASNELALFLARAVIDDVLAPFNLEEISSKLRPNSSGTETVKMARSLIFARHAGERLLRCWGGGSGWAVEDAKDKISNLLEEYESSGLVSEACKCIHELGMPFFNHEVVKKALVMGMEKKKDKMMLDLLQESFSEGLITTNQMTKGFTRVKDGLEDLALDIPNAKEKFNDYVEYGKKNGWVSSSFLTSLTEDANVG
The following text describes a protein:
Function:
Required for vacuolar biogenesis and for trafficking of hydrolase precursors to the vacuole. Mediates transport at the vacuolar membrane where it may be responsible for tethering transport vesicles on the target membranes. It is required for gluconeogenic growth of yeast. Acts as a component of the HOPS complex that acts during the docking stage of vacuole fusion. HOPS is an effector for the vacuolar Rab GTPase YPT7 and is required for vacuolar SNARE complex assembly. It remains bound to SNARE complexes after vacuole fusion. Acts as a component of the CORVET complex that is required for transport between endosome and vacuole. CORVET is an effector for the endosomal Rab GTPase VPS21. Probable ubiquitin-protein ligase involved in the degradation-related ubiquitination of histones. Contributes to the post-translational regulation of histone protein levels by polyubiquitination of excess histones for subsequent degradation.
Miscellaneous:
MISCELLANEOUS: Present with 1200 molecules/cell in log phase SD medium.
Subcellular Localization:
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSLSSWRQFQLFENIPIRDPNFGGDSLLYSDPTLCAATIVDPQTLIIAVNSNIIKVVKLNQSQVIHEFQSFPHDFQITFLKVINGEFLVALAESIGKPSLIRVYKLEKLPNREQLYHSQVELKNGNNTYPISVVSISNDLSCIVVGFINGKIILIRGDISRDRGSQQRIIYEDPSKEPITALFLNNDATACFAATTSRILLFNTTGRNRGRPSLVLNSKNGLDLNCGSFNPATNEFICCLSNFIEFFSSSGKKHQFAFDLSLRKRIFCVDKDHILIVTEETGVPTTSISVNELSPTIINRIFIIDAKNKIISLNFVVSSAIIDIFSTSQSGKNITYLLTSEGVMHRITPKSLENQINIIIQKELYPFALQLAKQHSLSPLDVQEIHKKYGDYLFKKGLRKEATDQYIQCLDVVETSEIISKFGVKEVPDPESMRNLADYLWSLIKNSISQRDHVTLLLIVLIKLKDVEGIDTFIQHFDRKGIWNEGVVMDDMDDVTFFYSDNDFFDLDLILELMKESDFKRLSYRLAKKYSKDSLIIVDILLNLLHNPVKAIKYIKSLPIDETLRCLVTYSKKLLEESPNETNALLIEVFTGKFKPSTFEVDLDRRDTTGDFSENIRTVFYSYKTFFNYMNSNGTSDAMSESSEASHEHEEPTYHPPKPSIVFSSFVTKPFEFVVFLEACLACYQQYEGFDEDRQVILTTLYDLYLNLAQNDVPERIDDWRSRATGVLRESNKLVYSAASNNTSKRVDNSIMLLISHMDQSSASAKDKTKIDIASFANDNPEMDLLSTFRAMTLNEEPSTCLKFLEKYGTEEPKLLQVALSYFVSNKLIFKEMGGNEVLKEKVLRPIIEGERMPLLDIIKALSRTNVAHFGLIQDIIIDHVKTEDTEIKRNEKLIESYDKELKEKNKKLKNTINSDQPLHVPLKNQTCFMCRLTLDIPVVFFKCGHIYHQHCLNEEEDTLESERKLFKCPKCLVDLETSNKLFEAQHEVVEKNDLLNFALNSEEGSRDRFKVITEFLGRGAISYSDITI
The following text describes a protein:
Function:
Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled repair (TCR) factor rhp26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation. Binds DNA.
Subcellular Localization:
Cytoplasm. Nucleus. Chromosome, telomere. Note=During transcription stress, localizes to the nucleus following proteolytic cleavage by the proteasome.
Sequence:
MSENKKFRPKKVGNTEQVSEKQHTDTALNISQDNKTSSSSAKRGAKGRRGTKGKSGPANSSQTSNIEGSNALELEFDRDSQLSVLQELFPSWTIDDLSFALEEADRDLELTILHITEGHASKWGEVKKKPIPKTKSKPTSHAPVSDNVSSTFRNATRKSKKPSASKDTSRGVRKSKAGAPSDPSSVHAPSSLEKPAGTGDLPSSEISTKAPASTTVSSSVDPGTINEDSSMKDHTTSNEQASVLTSANTAASTNTNGTAGGTSASAKSTSAADQAVASSKPIKKAWASVAKSKKKVTPAPAPAPESEPSKPSIAPSQPSKTNVSAAYEKPAELSSSSVPFPHKSQDSATPANVETTPSTATSAPKKSTAPFAINAVKPAPGLSNISSASLPKPSFAKQAAVGSQSSTTSMTTARLLSDRFPVVMPVANTAAIPEKVQVRFGSLTLGGEDKKSTKSSSDNIAQSGPRSSYFPKKTVSPKPEAKKEASKVAESTKIPKKQHTSAYESRAPQSKVPENLKESHVNETPYRGLHDVNLPASGNASSVSAIPPQVSAQTTIPAASTSATSGPVVGKQSAGYGGIYSPATHGISPQPYAGASLIPPSTGAAFNNETASSNAGETTALPYSSRFMNPVENRSANSPFDNFQHIDHSTELGYASNTSQQYQQTSHPAYTTMSPIEYGQAAPAAHYYNERNQYSQYDNVAGSASNTPDVHSVMHNKVASSNATSLPAAGTATPSPVVSQQQPQPYAFPPMYPIPYVSYGYGTMPYNNNKFGQPQQGYMSQSGFNDFPPIFGGHSNVYNRQQPGNVSGMSGTQTSNPINNATANTSGMTEKAAGHRDSVIGNGGVTGANSMSSTLGGLSSMSGMGRAAPGMFMGNVGSFENLSANAASPYGLPPQQTPLTNAATQQTTSFQSNANKVNNANSQPAGFPFNSGASTNAGSNGLGGYNAYNQSFINRPGGWYGNA
The following text describes a protein:
Function:
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Also binds to poly(L-proline) and phosphatidylinositol 4,5-bisphosphate micelles.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Also localized at cell-cell contacts at the early embryonic stages.
Sequence:
MSGWNAYIDTMTAAAPSIKRCAIVGAADGSVWARTEADNVFKASEEELKTFVALFNDVTQVPAKGADIEGVHYVVPRTEESLIFGKKENTGFFAVKTKSAVLIAVYEGPNEVAAQVRKAVESMQTYLNNAGY
The following text describes a protein:
Function:
Plays an important role in the elongation step of protein synthesis.
Sequence:
MSLGETACSYAALILHEDGISVTADKISTLLKTAKVPVDSYWPTLFAKLAEKKNLGDLIANAAGGGAPVAVAAAPVAAAAGGAAAAAPAAEEKKKNRKKRVMMIWDSACLIRDILNDLVKFCGSLPFKVTLDIVGFIFVLVIYICIRLDFVVLYELRNVGFMSI