lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Positively stimulates PRMT1-induced protein arginine methylation. Involved in skeletal homeostasis. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts.
Sequence:
MECDLMETDILESLEDLGYKGPLLEDGALSQAVSAGASSPEFTKLCAWLVSELRVLCKLEENVQATNSPSEAEEFQLEVSGLLGEMNCPYLSLTSGDVTKRLLIQKNCLLLLTYLISELEAARMLCVNAPPKKAQEGGGSEVFQELEGICIALGMSKPPANITMFQFFSGIEKKLKETLAKVPPNHVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGWSDRAKSQTEKLAKVYQPKRSVLSPKSTISVAHLLAARQDLSKILRTSSGSIGEKTACAINKVLMGRVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRHYTS
The following text describes a protein:
Function:
Transcriptional regulator with a general role in all morphogenetically distinct forms of filamentous growth, namely invasive growth and biofilm formation. May control FLO11 gene expression as part of a promoter-bound complex with FLO8 and MSS1. Important for virulence.
Subcellular Localization:
Nucleus.
Sequence:
MNGNNNTGNLQQSHGPPQQQQQQQMFNQTPQMGFQQAPPPGMQGRGNNAQTPLQQQRFNMSQQQMMAAQQQQQQQQLQQQNAMAAAAAAAAASGRPVPQRNPNYNGSPNPGQTLPLNNNNNNSNNNNNKTGMYNPNALATGMPSSNLQPTSSAGNSRGHTPRMVNQPQPFIPHQQNQPPLPPQQQQQQQQQQQQPTPQLPPQGQTPQQVQMGYPKKVNNGNLVANQSLKSGPMGGPVPMGGPQQARIPPNSSFQQSPQTQFAMPPNSNGPINPQQQQQQHGPNQNPQPTVSGRSPIQRQMIIATTTATGGKGDTNNSVQEQVQQEINTRIIKRNLGNAAIIRVLDLIEFISNQHYENLSNIEFWTKITPANFLPTAILKFNTTNITGGNGNKSLNDITGLNLNFLNSNKATSNNNNNNTNTNTNNSNNNNKPHQFELTTSTAPRFFASCIQTESILKCNISLSGSKFQVLSNGSIVIVSKIGLHFHYKDGSNSALHGTIKILMSKDLRIEWVDLNFSDYQSNISVSALEEKLKSIITDNTSITKKDIKRQKELLDELVKNSQASKLQLTFGIEPQSLRILQLGDVMSSMKSLMEFSMVNNIPSPMKSMELLIASQKNQQMQAFQAQMAVQAQAQAQAQVQAQAQGQNLANFSGSTNLQTDAQRSRQQQQQQQQQQQQQQQQQSLNTSNNNSNSNNSNNNNNNNSNNNNNNNNNNNGKGGIANGSNNISSPSPRTVNAEEPKRKRKQSVNMSNENKRRK
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing; Probable common Sm protein, is found in U1 and U2 snRNPs and may be part of the spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MSKGGQAPDLKKYMDKRLNIKLNANRTVVGVLRGFDQFMNIVLDNSVELTKGGEENEIGMVVIRGNSVVMIEALEHIETKEVPGNR
The following text describes a protein:
Function:
Attaches a phycocyanobilin (PCB) chromophore to 'Cys-153' of the C-phycocyanin beta subunit (PhcB). It does not attach chromophore to CpcA, ApcA or ApcB, the other phycobiliproteins.
Sequence:
MSHSTDAHTLARWMAGEFSNEAQALANPPLWAHIKVCMRPLPNQFFDGYGLYLEQAYSSDTSAPYRLRLFHIKPVDDHMELVHYKPKDDAKTKYMGAARNPAMMQHFDMADLDPMPGCDMIVTWSGTSFKGTVQAGKGCRVVRYNKESYLDNSFEITDNALISIDRGRDPVTNEILWGSLAGAFEFEKINNFSGEVQPH
The following text describes a protein:
Function:
May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association (By similarity).
Subcellular Localization:
Nucleus. Note=Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm.
Sequence:
MSFMGLPLAGQKHCPKSGQMEAMVMTCSLCHQDLPGMGSHLLSCQHLLRKDCFQGLIQELGQIAKAHETVADELISCPGCERVYLTRDVTEHFFLHCVPTEQPKMARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKMESEDSTRFTDLLGQGPIVPGLDAPKDLAIPSELEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKVTVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV
The following text describes a protein:
Function:
Probable lipase required downstream of MPK4 for accumulation of the plant defense-potentiating molecule, salicylic acid, thus contributing to the plant innate immunity against invasive biotrophic pathogens and to defense mechanisms upon recognition of microbe-associated molecular patterns (MAMPs). Participates in the regulation of various molecular and physiological processes that influence fitness. Together with SG101, required for programmed cell death (PCD) triggered by NBS-LRR resistance proteins (e.g. RPS4, RPW8.1 and RPW8.2) in response to the fungal toxin fumonisin B1 (FB1) and avirulent pathogens (e.g. P.syringae pv. tomato strain DC3000 avrRps4 and pv. maculicola, turnip crinkle virus (TCV), and H.arabidopsidis isolates CALA2, EMOY2, EMWA1 and HIND4). Together with EDS1, confers a basal resistance by restricting the growth of virulent pathogens (e.g. H.arabidopsidis isolates NOCO2 and EMCO5, E.orontii isolate MGH, and P.syringae pv. tomato strain DC3000 or expressing HopW1-1 (HopPmaA)). Necessary for the salicylic acid-(SA-) dependent systemic acquired resistance (SAR) response that involves expression of multiple defense responses, including synthesis of the phytoalexin camalexin and expression of pathogenesis-related genes (e.g. PR1, ALD1, BGL2 and PR5) in response to pathogens, triggering a signal amplification loop that increases SA levels via EDS5 and SID2, but, together with EDS1, seems to repress the ethylene/jasmonic acid (ET/JA) defense pathway. May also function in response to abiotic stresses such as UV-C light and LSD1-dependent acclimatization to light conditions that promote excess excitation energy (EEE), probably by transducing redox signals and modulating stomatal conductance. Regulates the formation of lysigenous aerenchyma in hypocotyls in response to hypoxia, maybe via hydrogen peroxide production. Modulates leaf senescence in insect-infested tissue and triggers a phloem-based defense mechanism including antibiosis (e.g. green peach aphid (GPA), M.persicae) to limit phloem sap uptake and insect growth, thus providing an EDS1-independent basal resistance to insects. Also involved in regulation of root meristematic zone-targeted growth arrest together with EDS1 and in a VICTR-dependent manner.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Can move to the cytoplasm when in complex with EDS1.
Sequence:
MDDCRFETSELQASVMISTPLFTDSWSSCNTANCNGSIKIHDIAGITYVAIPAVSMIQLGNLVGLPVTGDVLFPGLSSDEPLPMVDAAILKLFLQLKIKEGLELELLGKKLVVITGHSTGGALAAFTALWLLSQSSPPSFRVFCITFGSPLLGNQSLSTSISRSRLAHNFCHVVSIHDLVPRSSNEQFWPFGTYLFCSDKGGVCLDNAGSVRLMFNILNTTATQNTEEHQRYGHYVFTLSHMFLKSRSFLGGSIPDNSYQAGVALAVEALGFSNDDTSGVLVKECIETATRIVRAPILRSAELANELASVLPARLEIQWYKDRCDASEEQLGYYDFFKRYSLKRDFKVNMSRIRLAKFWDTVIKMVETNELPFDFHLGKKWIYASQFYQLLAEPLDIANFYKNRDIKTGGHYLEGNRPKRYEVIDKWQKGVKVPEECVRSRYASTTQDTCFWAKLEQAKEWLDEARKESSDPQRRSLLREKIVPFESYANTLVTKKEVSLDVKAKNSSYSVWEANLKEFKCKMGYENEIEMVVDESDAMET
The following text describes a protein:
Function:
Transcriptional trans-activator of the gene (mprA) for the small neutral protease.
Sequence:
MELEVRHLRALCAIADAGSLHRAARRLGVAQPTLSTQLTRIEQALGGPLFTRERTGCRPTPLGRTVLGRARPLLTDMNTLVREARAAAAGGDSRLRVGSTASRALAGWLRRLRRPGLEPTLQMDVSANALLRRVTDGQLDVAFVHEVEGCALHIPEDLRLRVLVEREPQFVMLPADHPAAARPVVRLADLADDRWMVDPTVDGEWDGVHRMLRAVGLNPRVLHGDYHTAASLVATGEVVTVCQPSSQSRPDTAVRRLYGDPLGVRLLLAARTRAELDAVFPALEDAYWEAARQSTAYREWLEGGGIRTLPRCPVAATGGGRVEFVRAR
The following text describes a protein:
Function:
Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs. Can transport lactose and glucose.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MHNSPAVSSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTDEVHARPAMVGFFFTGSAVIGILVSQFLAGRSDKRGDRKSLIVFCCLLGVLACTLFAWNRNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGPPLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMRKELPLATGTIEAPRRNRRDTLLLFVICTLMWGSNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFAKRLGKRFLMRVAAVGGVCFYAGMLMAHSPVILLGLQLLNAIFIGILGGIGMLYFQDLMPGQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKDV
The following text describes a protein:
Function:
Has highest activity on the linear beta-1,6-glucan pustulan. Lower activity against yeast glucan and laminarin (beta-1,3-glucans with beta-1,6-branches). No activity on colloidal chitin, pachyman, starch, cellulose, nigeran, dextran or gentobiose.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MRYALIASMLGQAAISVAMPSEPAHSPRAAGAQAYASNQAGNYKLTSIAAPVQGNGSPGPSTWNLSIDDTSSGYKQKIVGFGAAVTDATVSAFNELSASTLSQLLDELMTGAGASFSLMRHTIGASDLSGDPAYTYDDNGGNADPGMTGFNLGDRGTAMATMLAQMKGLNSNLQIFGSPWSAPGWMKLNNAIDGNTNNNNLNDGYLTNNGAQYSAAFAQYFVKYIQAFESHGATINAITLQNEPLNSQAGYPTMYMFSYEQGDLIQNYVAPALKAAGLSTKIWAYDHNTDQPDFPEQVMGIAADDVSAVAWHCYATNLDWTVLTNFHNSYPNTDQYMTECWTPSTGAWNQAASFTMGPLQNWARGVAAWTLGTTAQDGPHLSSGGCGTCTGLVTINNGQYTFQTAYYMMAQFSKFMPVGATVLSGTGSYTYSGSGGVQSVASLNPDGTRTVVIENTFGNDIYIHLSTSSGQEWSGNVPTNSVTTWVLPAV
The following text describes a protein:
Function:
Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. May play a role in SDF1A-stimulated chemotaxis.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MAYCWKTDLNTSESHQEQHEHQEFHSVNQFLSPNQVSLGFDQLVDEISNKVPLYQTDIEENTIFVPSAPTWDSRRHSLDETHQISLNELTAKSSELSCHRIRKTPVIGFRSSVLQNPENTNKGSSWGNPTGKYQGADDYRFNILASSSTSLHEINSQRELENENPNYHIGFESSIPSMYPSFSTDFMPKEENERSRNMNTVQHSLMLFEGSFLPRARESTWPKIIQLTGCSSQLVEVPQGTNKDLASFCNKVKKIREMYHAADINSNSGKIWSTTTAFPYQLFSNTKFNINICIDNSTQLLHFMPNANYLVKDLIAEILHFCTNDQLFPKDHLLSVCGYEEFLQNDYSLGCHKIFQKDKSVIQLNLQKNGEVPGKLSRKHEDDHSQFYLKQLLEFMHIWKVSRQCLSTVIKKYDFHLKCLLKTQQHVDNIIEDVKNICSVLGCVETKQITDAVNELNQILQRKTENFHQNSETSAKGLIERVTTALSRSIYQLISVYCCSFYADFQPLNVPNDISYLNPGLHSHLSFTVYAVHNIPETWVHSYKAFSFSCCLTYAGKKLCQVRSYRNIPFKKLFFLLVNWNETINFPLEIKSLPRESMLTIRLFGIVCATNNANLLAWTCLPLFPKDKSILGSVLSSMTLQNEPPIEMIVPGVWDISQPSSVILQIDFPATELEYMKFDSEENRSNLEEPPKECLKHIARLSQKQSPLLLSEEKKRYLWFYRFYCNNENCSLPLVLGSAPGWDVRTVSEIHTILRRWQFSCPLEALGLLTSSFPDQEIRKVAVRQLDNLLNDELLEYLPQLVQAVKFEWNLESPLVQLLLHRSLQSIQIAHRLYWLLKDAQNETYFKSWYQKLLAALQFCSGKALSDEFSKEKKLIKILGDIGEKVKSASDPQRQEVLKKEIGRLEEFFQCIKTCHLPLNPALCIKGIDRDACSYFTSHALPLKITFINANPMGKNISIIFKAGDDLRQDMLVLQIIQVMDNIWLQEGLDMQMIIYRCLSTGKGQGLVQMVPDAITLAKIHRHSGLIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGGKNPQHFQDFVELCCQAYNIVRRHSRLLLNLLEMMLHAGLPELGGIQDLKYVYNNLRPQDTDLEATSHFTKKIKESLECFPVKLNNLIHTLAQMTSINPAKSASQNFSQESCMLNATRSIQRATILGFSKKTSHLYLIQVTHSNNETSFSEKSFDQFSKLHSELQKQFASLTLPEFPHWWHLPFTNSNHKRFRDLNHYMEQILNGSYEVANSDCVLSFFLSEPVQQTIEESSLLDLGEKFPDKMPMVQLVISHEDAKLTILVKHMKNIHLPDGSAPSAHVEFYLLPYPSEVRRRKTKSVPKCTDPTYNEIVVYNEVTELRGHVLMLIVKSKTVFVGAINIQLYSVPLNEEKWYPLGNCII
The following text describes a protein:
Function:
DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots; Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MMADSGRDGASNEEDILTLFEGFRGELEASNAVREEIKAVSQSMDAETRKMQAALMGIHAGTDEAVASAVAKVREHLEPLRTLNAQLAAIMKQHPGQYYRYHDIWRHVHTSCAFLVAFVHWLEHGTLLTHAQVESELQLRHEEFGIDLEDYLVGVCSVSNEMPRYVVNRVTAGDYDCPAKVASFLSDLYAAFRLLNLRNDFLRKRFDGLKYDLKRVEEVLYDVKIRGLQSRSQPG
The following text describes a protein:
Function:
This satellite DNA-associated protein is a double-stranded DNA binding protein specific for tracts of pure at DNA. It may play a role in organizing the higher-order structure of euchromatin as well as heterochromatin.
Miscellaneous:
MISCELLANEOUS: D1 may be the most abundant member of a small family of D1-like proteins.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MEEVAVKKRGRPSKASVGGKSSTAAVAAISPGIKKRGRPAKNKGSSGGGGQRGRPPKASKIQNDEDPEDEGEEDGDGDGSGAELANNSSPSPTKGRGRPKSSGGAGSGSGDSVKTPGSAKKRKAGRPKKHQPSDSENEDDQDEDDDGNSSIEERRPVGRPSAGSVNLNISRTGRGLGRPKKRAVESNGDGEPQVPKKRGRPPQNKSGSGGSTGYVPTGRPRGRPKANAAPVEKHEDNDDDQDDENSGEEEHSSPEKTVVAPKKRGRPSLAAGKVSKEETTKPRSRPAKNIDDDADDADSADQGQHNSKKESNDEDRAVDGTPTKGDGLKWNSDGENDANDGYVSDNYNDSESVAA
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Sequence:
MMNVLQIVRDHWVHILVPVGFVFGCYLDRRSDEKLTAFRNKSLLFKRELRPNEEVTWK
The following text describes a protein:
Function:
Plays a role in regulation of the unfolded protein response triggered by endoplasmic reticulum (ER) stress resulting from the presence of unfolded proteins in the ER lumen.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein.
Sequence:
MLRRLTRPQLLFAAALGVAGGMYIYQPIFEQYSRDQKELKEKVKILQESEEKRS
The following text describes a protein:
Function:
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
Subcellular Localization:
Secreted.
Sequence:
MDRLLLVLLSSASLLLTVYGIKHHIVTKSWSEAQSDCLQYLRVESPGRYLSHRYRDNQTSKQLIFCIILNLRIYDPTQNVLRLKAMGQFFNPDKTDTLYVNRTNACLLRVKVPPLVDSSEDSQLYSGVMGTLYEVFRCFYHCYGNINAIAPKLPPTVLELEKIQQECARMVGVSERLLDGGLQLSSHPRYSKLPRCIMLRSGGSVDYLTHRNNSSRRFKLKKNVENDTL
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates transcriptional activation of the fecABCDE operon which mediates ferric citrate transport.
Sequence:
MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQDTFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPEERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKAVEHCLLFRLEYGL
The following text describes a protein:
Function:
Orphan nuclear receptor. Transcriptional repressor of intestinal metal transporter smf-3 and genes of the innate immune response. Inhibits nuclear localization of transcription factor pqm-1; in response to pathogen stress, may facilitate translocation of pqm-1, leading to transcriptional activation of genes involved in innate immunity and iron uptake.
Subcellular Localization:
Nucleus.
Sequence:
MDFLISTSLSESTSTSADFCVVCGDKAIGKHYGAVACNGCKGFFRRSVWQNLQYTCRFNKQCNIDKDHRNACRYCRFQKCLADGMKPEAIQNERDRIGSTKRRKRSGANSENNSDSEGTPSPKIEVMGNSVSRKLIEMLLDIEHRLASNQSMNALLRDESEMKNSRQRAVNYLIGWTNMLHPLPEVPLADKVLLLKKFSSAFTLLGTLQRSMALPHFVLPNDQVLSISASHPPELFEALTRIIDELLTPLRRLRTDHAEFSCLKALLLLNPDVVGISNNTRERIREARDALLKTLFAYMSNTQNSIDASLRVSSLLMIIPSLISVSSSIMEFPALSDLFGLGDVIKRDTISPKIETPPLEMKPMMPKIAQPPVTSAPTVPTNIMMNKDLISQIMNNPQLFPLLPMPQTASPPMSFMGQSEFGCHLQSMPVKVILS
The following text describes a protein:
Function:
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
Subcellular Localization:
Cytoplasm.
Sequence:
MSGFFITATDTEVGKTVVAGAIAGVFRELGYNVGVYKPLQSGHVASNPEGDAARLKSLSGVPTQENEICPYSIEEPLAPRLAMKRAGRVVKLKEITDYYNGLLKEFNSLFVEGAGGLAVPYTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAKAHGLTVAGVILSGCKECEMERVQENKEMIEELSGVPVLGLLPFFAGEFTKEEVLESAKEHIMISKLEEFIQNESNVAGAPSM
The following text describes a protein:
Function:
Probable subunit of an amino acid transporter involved in the regulation of the amino acid metabolism. Stimulates amino acid export by activating nonselective amino acid facilitators.
Miscellaneous:
MISCELLANEOUS: Overexpression of GLUTAMINE DUMPER 7 leads to free amino acid levels accumulation.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The VIMAG motif is necessary for the function of the protein.
Sequence:
MSLHRDSMVPVNSRLENMDSPILSKICAWGVMLGLFALSLFAMAYACYHKQTSNSCIEEKQGKKQVLKPLDMEPKIVVIMAGNENPTFFAKPTQINA
The following text describes a protein:
Function:
Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex (By similarity). Involved in steering cell migration by controlling its directional persistence.
Sequence:
MSSSTNYSGTFTKERFCGGDGFIVEGILQKHNIHTVFLQAKQPLQDTVLPTRYVAITIEFDNAVKRNWKDGVEIPPKMTRATAITKGYLNKFDRVQATLVDKINADQLSVAISDGNKNSSLPSNFHDDAIKNLHPNKKNYFEFWADVDKFSHKIFKSGDEVRIKTIGDSIFVDSVVKMDSNNIANFSGDSNLGDSFASNIMKRYDQIESNNQQQQEEEDDDEWK
The following text describes a protein:
Function:
Contributes to virulence by binding to the host IKBKB subunit of the IKK complex and preventing host NF-kappa-B activation in response to pro-inflammatory stimuli such as TNF-alpha or IL1B. Mechanistically, sterically hinders the direct contact between the kinase domains of IKBKB in the IKK complex containing IKBKB, CHUK/IKKA and NEMO.
Sequence:
MTANFSTHVFSPQHCGCDRLTSIDDVRQCLTEYIYWSSYAYRNRQCAGQLYSTLLSFRDDAELVFIDIRELVKNMPWDDVKDCAEIIRCYIPDEQKTIREISAIIGLCAYAATYWGGEDHPTSNSLNALFVMLEMLNYVDYNIIFRRMN
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MVKFSAGCVALSLCCCLWLAFLAGLPAEAARGGKKETVEETVKRVVGTAMEGSGRRLGAALVRLLFHDCWVQGCDASVLLDTVPAGSGTGEKDAKNNNGLDGFNLIDDIKAELVRLGETNVSCADILVLAARDATAILSGGTINYAIKRGRVDGVVSSASDADAILPPSTFKIKQLKDNFALKGFTTRELVALSGAHAVGVAHLQSFADRLNSSTETPIDGAYRNALRNHTEAQKTAQGTNDPIELNNIRDMDGKFQTDAGYDATGVNTAVVGVLDNSYYKANLQNRVLFRSDWELRNDTDTAANAGIALAEFGSSASKWFVAFSNAMAKLSDLRAEGPRFEIRKNCRKIN
The following text describes a protein:
Function:
Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
Domain:
The HA-stretch region of HTR3B seems to confer increased conductance to HTR3A/HTR3B heteromers compared to that of HTR3A homomers.
Sequence:
MLSSVMAPLWACILVAAGILATDTHHPQDSALYHLSKQLLQKYHKEVRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWNSSMFDEIREISLPLSAIWAPDIIINEFVDIERYPDLPYVYVNSSGTIENYKPIQVVSACSLETYAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWELLSVSSTYSILQSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTSVLVGYTVFRVNMSNQVPRSVGSTPLIGHFFTICMAFLVLSLAKSIVLVKFLHDEQRGGQEQPFLCLRGDTDADRPRVEPRAQRAVVTESSLYGEHLAQPGTLKEVWSQLQSISNYLQTQDQTDQQEAEWLVLLSRFDRLLFQSYLFMLGIYTITLCSLWALWGGV
The following text describes a protein:
Function:
Induces apoptosis and anoikis.
Miscellaneous:
MISCELLANEOUS: [Isoform BOD-S]: Produced by alternative initiation at Met-104 of isoform BOD-L.
Subcellular Localization:
Membrane; Peripheral membrane protein. Mitochondrion. Note=Associated with intracytoplasmic membranes.
Domain:
The BH3 motif is required for the interaction with Bcl-2 proteins and cytotoxicity.
Sequence:
MAKQPSDVNSECDREGGQLQPAERPPQLRPGAPTSLQTESQGNPDGEGDRCPHGSPQGPLAPPASPGPFATRSPLFIFVRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASIRQSQEEPEDLRPEIRIAQELRRIGDEFNETYTRRAFANDYREAEDHPQMVILQLLRFIFRLVWRRH
The following text describes a protein:
Function:
Small subunit of the propanediol dehydratase-reactivating factor (DDR), which reactivates suicidally inhibited adenosylcobalamin-dependent propanediol dehydratase (diol dehydratase, DDH) found in the bacterial microcompartment (BMC) dedicated to 1,2-propanediol (1,2-PD) degradation. Reactivates inactivated DDH in the presence of ATP, Mg(2+) and free adenosylcobalamin (AdoCbl), by mediating the exchange of the tightly bound damaged cofactor AdoCbl for a free intact one; The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
Miscellaneous:
MISCELLANEOUS: Bacterial microcompartments (BMC) 100-200 nm in cross section are formed during aerobic growth on minimal 1,2-PD-B12 or anaerobic growth on 1,2-PD-tetrathionate medium, but not during aerobic growth on glucose, anerobic growth on glucose or pyruvate-tetrathionate. BMCs can constitute up to 10% of total cell protein.
Subcellular Localization:
Bacterial microcompartment.
Sequence:
MDSNHSAPAIVITVINDCASLWHEVLLGIEEEGIPFLLQHHPAGDIVDSAWQAARSSPLLVGIACDRHSLVVHYKNLPASAPLFTLMHHQDSQAQRNTGNNAARLVKGIPFRDLHA
The following text describes a protein:
Function:
[Isoform a]: Voltage-gated chloride channel. Insensitive to depolarizing conditioning voltages, requires low voltages for activation, insensitive to chloride levels and has a mild sensitivity to low pH. Channel gating properties are conferred by the cytoplasmic C-terminus. Plays a role in egg laying by modulating hermaphrodite-specific neurons (HSN) excitability and the ovulatory contractions of gap-junction-coupled gonadal sheath cells. When active, may prevent tubular formation of the excretory canals. Activated during oocyte meiotic maturation and by membrane hyperpolarization and cell swelling. Inhibited by Zn(2+) and to a lesser extent by Cd(2+); [Isoform b]: Voltage-gated chloride channel. Sensitive to depolarizing conditioning voltages, requires stronger voltages for activation and activation is slower, is inhibited by low concentrations of chloride and is activated by low pH. Channel gating properties are conferred by the cytoplasmic C-terminus.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Domain:
The CBS domains, the R-helix linker (543-562) and the C-terminal domain (833-1001) regulate channel sensitivity to voltage, pH and extracellular chloride concentrations, probably by altering the outer pore structure. The region (738-751) between the CBS domains is essential for channel activation.
Sequence:
MGIGTKILSKIEKNKTSDGLTIPLTPTTQKQSSSWCSFESIKTFFRTVIRDWIFLALLGFIMASLSFGMDYAILNLQNGQMRLFDLVKEYHFTLAYLVWVGYVVGLILLSAVCAHYIAPQAIGSGIPEMKTILRGVILKEYLSVRTLLSKMIGLTLSLGSGLPMGKEGPFVHVASVVASQLTRLVHGSSGGIFENESRSGEMLAAGCAVGVACTFSAPIGGVLFSIEVTSVYFAVRNYWRGFFAATCSATLFRILRMFSVSAAVTVEAHYQTNFPPQNVFLPQELPIFALIGLVCGLAGSIFVYLHRRTVLFLRRNWLAKMIFQKYWLIYPIFIATFISSLSFPLGLGKFMGGEERFSHTMKEFFVDCAWTAPPNDSYACPMPTSNATSSDSFDIRHWKGDNYDYSPFVTLSSFQVVYFFLAILASTLPVPSGIFMPVFVLGAAFGRLVGEGVFSLDPYGHISGDIQFFVRPGVYAVVGAAAFCGAVTHTVSVAVIVFELTGQLCHLLPVMIAVLIANAVASYLQPSIYDSIIRIKNLPYLPDIPHTTSLYHQMLIEQFMISPLVYIAKDSTVGDIKRALETKTRIRAFPLVENMESLALVGSVSRSQLQRYVDSQIGTKARFAEATRRIKQRLEDEESERKRREESKSDDTEDSLETTGAGERRASRFLIVPVAKNGPQVAKNETLTGLSEENARKILTVEEKQALFDAASLATPKREMSGKTINPVHIESHHTIGDIFRSITHLSFGRQNFPKKNNHNEFDLFGEERTEWEDMMLNQKLDLSQLDIDSTPFQLSEYTSLFKAHSLFSLLGLNRAYVTKKGQLIGVVALKELRLAIEYLQSGKVPTPGMSIFNEPPTEQSIYEKSARLESGRATGDAQNAAFVTDNGEDDAQNDYIQPPLEVVRRGALTPNRMSELTRLENVRTTPESPHFEVSSPSTSSSCVSIDFSPLDAANSENGSVGGLVLNVPSLPTRARSANELTRQNTHVQINLPDDVHDEKF
The following text describes a protein:
Function:
The complex LTO1:YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSWVQAASLIQGPGDKGDVFDEEADESLLAQREWQSNMQRRVKEGYRDGIDAGKAVTLQQGFNQGYKKGAEVILNYGRLRGTLSALLSWCHLHNNNSTLINKINNLLDAVGQCEEYVLKHLKSITPPSHVVDLLDSIEDMDLCHVVPAEKKIDEAKDERLCENNAEFNKNCSKSHSGIDCSYVECCRTQEHAHSENPSPTWILEQTASLVKQLGLSVDVLQHLKQL