lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a key role in hydrogen peroxide removal.
Miscellaneous:
MISCELLANEOUS: Binds one cation per subunit; probably K(+), but might also be Ca(2+).
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MAAPVVDAEYLRQVDRARRHLRALISSKGCAPIMLRLAWHDAGTYDVNTKTGGANGSIRYEEEYTHGSNAGLKIAIDLLEPIKAKSPKITYADLYQLAGVVAVEVTGGPTVEFIPGRRDSSVCPREGRLPDAKKGALHLRDIFYRMGLSDKDIVALSGGHTLGRAHPERSGFEGAWTQEPLKFDNSYFLELLKGESEGLLKLPTDKALLEDPSFRRYVDLYARDEDTFFKDYAESHKKLSELGFTPRSSGPASTKSDLSTGAVLAQSAVGVAVAAAVVIVSYLYEASKKSK
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MTVELMMSSYSGGGGGGDGFPAIAAAAKMEDTALREAASAGIHGVEEFLKLIGQSQQPTEKSQTEITAVTDVAVNSFKKVISLLGRSRTGHARFRRAPASTQTPFKQTPVVEEEVEVEEKKPETSSVLTKQKTEQYHGGGSAFRVYCPTPIHRRPPLSHNNNNNQNQTKNGSSSSSPPMLANGAPSTINFAPSPPVSATNSFMSSHRCDTDSTHMSSGFEFTNPSQLSGSRGKPPLSSASLKRRCNSSPSSRCHCSKKRKSRVKRVIRVPAVSSKMADIPSDEFSWRKYGQKPIKGSPHPRGYYKCSSVRGCPARKHVERALDDAMMLIVTYEGDHNHALVLETTTMNHDKTL
The following text describes a protein:
Function:
E3 ubiquitin ligase.
Subcellular Localization:
Cytoplasm.
Sequence:
MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGNRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDGADSPSEDSEKPRVLYSLEFTFDADARVAITIYCQAAEEFLNGTAVYSPRSPALQSETVHYKRGVSQQFSLPSFKIDFSEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKIVKCFQHQPVAWLDEDQGPWEETRLRLLLLDLAPHVGILLTPRFLSPHVDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDEENSDNSNECVVCLSDLRDTLILPCRHLCLCNSCADTLRYQASNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSMDHDEHSCPFKKSKAHPASLASKKPKRETSSDSVPPGYEPISLLEALNGLRAISPAIPSAPLYEEITYSGVSDGLSQASCPLAGIDRILESSHQKGKPRSRSPDSTLRSPSSPIHEEDEEKLSQDSDAPPPLSGVGLALSSSPESFVTEEADEAAALKQGSRVPSIENVLQDGSPEPCSHGQPRLPADIYLPGWSTSMEPPHSLRTTGPPRPVLGGPSPDPGATELTPL
The following text describes a protein:
Function:
Involved in DNA repair and RecF pathway recombination.
Sequence:
MIFLRGKGIIIAKKDIEEADRYITIFMEDYGKVSTVIKGIRKSKKRDKTAVDILSLTDFQFYKKNDSLIISNFSTVKDYIGIKSDIDKINIAFYIFSILNQILVENGRNRKIYEVLEKTLDYLNTSNDERKNYLLILFFLNTLIKEEGISLEDNSNMEELQVVVETQRKVEIDDNVKRILQYLFEDNLKVVINDEKYKINYIRKAILVLENYINFHLDTNINAQKILWGALLW
The following text describes a protein:
Function:
Uniporter that mediates the transport of extracellular choline and ethanolamine into cells, thereby playing a key role in phospholipid biosynthesis. Choline and ethanolamine are the precursors of phosphatidylcholine and phosphatidylethanolamine, respectively, the two most abundant phospholipids. Transport is not coupled with proton transport and is exclusively driven by the choline (or ethanolamine) gradient across the plasma membrane. Also acts as a heme b transporter that mediates heme efflux from the cytoplasm to the extracellular compartment.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDLKHSNVPEVTVVADAYMPGSKSSDLIKPPATNGSNATLDKPALPAGEFRMYSRRWLVLAIFVMYSASNALQWIQYSIIANIVQRYYNITSTWVDWTSMIFMILYIPLIFPASWILDKLGLRIAAISGVLGTCIGAWVKCFSVSPDLFWVGFVGQSIVAASQVFILSLPAKVAAVWFGPDQVSSACSIGVFGNQLGIAVGFLVPPMLVENHDDINLIGDDLRLMFYIVAGFTSVLVVLVLFFFKAAPPTPPSAAQEATKTPNPLQSSPFLHSIKRLMLNRNYVLLLISYGMNVGVFYAISTLLNQIVLTHYPGHEVDAGRIGVCIVFAGMLGSVACGIVLDKTHRFKETTLAVYIFTMIGMWIYTFTLSVGHIAVVYVTSALLGFFMTGYLPVGFEFAAELTYPEPEGTSTGLLNAAAQVFGITFTMLYSELLNTNGDIVANVTMAVMLLVGSVVTAVIRSDLRRQAAQNPNP
The following text describes a protein:
Function:
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.
Subcellular Localization:
Nucleus.
Sequence:
MEQQQLLTPDLLLVAGNSDSFVVDDLLDFSNDNGQPDDGFEPFPDSSTVYAGNLAVSSNSSSLYTDGSAFSEDLCVPCEDLAELEWLSNFVEDSFSKEDQDKLQLLSGSLQKPQTTGSRSAASTWASRLLAIAGSDEPFPKKKHHKLKEHDSSGEYEVDGGEAEVERRCLHCATDKTPQWRTGPMGPKTLCNACGVRYKSGRLVPEYRPASSPTFVMARHSNSHRKVMELRRQKEVRDEHLLSQLRCENLLMDIRSNGDDFLIRNDNNHVAPDFRHLI
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MVFEKVKNIIVEQLGLDEGEVKLETSFEDLGVDSLDLFQIIIEIEEAFDIQVEEAEKIKTVEEAVKYVESKIEK
The following text describes a protein:
Function:
Component of the set3 histone deacetylase complex which is involved in chromatin remodeling and transcription regulation, such as repression of the sporulation gene program.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDTNQVNYIIWRYLKECGYSHTKFAFERETGIQNLDKQWGSTCQVGALVEILQKGLQYVELEKHYVDNHSSNEEASKTSIDGESLVNENPCKLPFYLTVPHICETTLTKADSTNGFCEHNNSNDHQLKILQDKGSGSPSSPVMPFKDKIEKRDIDITMADESNVEKDPARPIAVYNSSPVTEITEIKQVTFTGGEDIKSDFFKVIPTKHPVTCADWRPLLQENYHVYEFSIGMTNATLASVSICEEQNDFKAKTDYCLQSSFDNQDITGVAWNNSGSFLAYAFFSGVIEIYDSHGSQILSFHNNKGPVLSLKWSGTDTYLAAGSADGTITLFDQLKQTQYSIDTLASSVLDIEWISFDEFVTSDVEGSLRVYKVDGKAPVSTVSHAHDNSIVALRYNLRISLLLTASSDTTVKLWSRGDAGAFECLHVFSFSSPVNCIDWNLREGTPILAVASNSIVSMYNAISLQQLAVFMRHTAPVSALSFSHNGRYLATGDTSGGVCIWSCKTAKLFKELGSDNSELIAVTNVLPEEQVNFLRWSFDDKDLLIGKQKKEIICCCDFLHDSL
The following text describes a protein:
Function:
Required for arbuscular mycorrhiza (AM) development during AM symbiosis with AM fungi (e.g. Glomeromycota intraradices).
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MVWKLTGKYLDVIIFQGLQLEGEATKLKVEKGIVAIFLDTKYELHTTRSPIFLGLEPAKSTNMWSEKLASHDVIVGVLDTGIWPESESFKDVGMRPVPAYWEGACEIGTSFTKSHCNKKVVGVRVFYHGYEAVVGRINEQKEYKSPRDQDRHGTHAVATVGGSPMHGANLLGYANGITRGMAPGERIAAYKVCWVGGYFNSDIVSAIDKVVADGVNVLYTSLGGGVSSYYRDSLSMIAFEAMERCVFVSCSAGNAGPDPASLTNVSPWITIVGGNTMDRDFLVDVRLGNGKKMIGVSLYKWKNVLSIEKQYPWVYMVSNSSRVDPRSICLEGTLDPKVLSGKIVICDRSLSPRVQKGDVVRSLGGVGMILTNTEANGEELVADSHLLLVVEIGEKEGKKLKSYLLSSKSSTATLAFKGTRLGIKPSPVVAAFSSRRPNFLTLEILKPNLVAPAVNILVAWSEAIRPSSLKINNRKVKFNIVSGTSMSCPHVSGIATLVKSRHPEWSPTTVKPALMTTTYVLDNTKKTLRDASIAKPFSPYDHGLRHIDPIRALDPSLVYDIMPQDYFEFLPVIVHKTITNVGPPDSKYHVMVSPFKGASMKVEPKTLNFIEKHQKLSCKITFKPKIQQTSPEFGSMEWKDGLHTMRSPIVITWMPPPM
The following text describes a protein:
Function:
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
Subcellular Localization:
Nucleus.
Sequence:
MASFHLDHLKNYHRRFCRPSRAPNIPTKQGQNMLEILQDCFEEQNSTESLSCSTPKEKDIYVQSTGKERQASHSESVPISSRRKEASLQVPAKPSDPADEPVQANEVHQKILSTDVVSKSTPDSTKTSSKGVKGHHGASDELYLPGGSPVVLLGARVSGSQKAISSGGQKRVTSRRSADMQSSNTDISFKTRKRLNFEDKVISNTAEIESSASQVEDSISEEQEGTSSETSQKRDDLSSEIQPQSKKSFSELYLETVNRKSKCSSVVRHTAAVPSPPYPPNDMKLLEDEFIIDGPDRSFSSQPWVVIPRKGHHMPFPENIAVPQGKKSREKPHRLSEKTLVSNTQTDKTGPVEEAQLSVEEKLGTTLTNELENDCRSTENKTHSENAKKPSARKRTVKQKQRRPSKPNIAQELSMGQNETENRNMSKIGQDKLQINSKRNMEDHEEVRNEPTPKKPVPALGNKKEKDSTQANKEKSRKKCFSRESKRKSVPKEVTLASRRGRRTSQHPSEWWLVKPSEGSVDGNSSKENESSILYPNRKKQTKRNHVSENTEKKPVPSKRKKKEISSRELKSLNVKGSGGNDDISTSQRKPLQNIDADPTQKSLHCSGPTRGSEDQNSDMISQNVHLKTRSEQHRSKTQMESTSNSEVCKHSVWEESGPSRFKNLEMPGRSNSEVGDEKDQKSLDLKTRSSNMVPNRNLHHKLVLPSNSPNVRRSNRIRLKPLEYWRGERIDYQESSSGRLVLEIVSPASESVKRKAKRNLDKVNKETNKKRIHLDNPTKTKIKVSLDIPLGDPFQATLAKDPETREIVPMDLIRPRDTYHFFVEQHGLKVYKTLNTTFFSTGKLVLGPHEEKGKQHVGQDILVFYVNFGDLLCTLHETPYMLTTGDSFYVPSGNHYNIKNLLNVESCLLFTQIKR
The following text describes a protein:
Function:
Anion-transporting ATPase. Catalyzes the extrusion of arsenite.
Sequence:
MRILIYTGKGGVGKTSIAAATAVFLANSGEKVILMSTDQAHSLGDVLDKKLNGEICQVFQNLDVVEIDTIEESQKVWRNLQDYLKQIISAKANNGIEIDEALLFPGLEEIFSLLKILDIYEANEYDVMVVDCAPTGQSLSMLTYSEKLNMLADTILPMVQSINSIFGSFISKKTSVPKPRDIIFEEFKNLVKRLTKLYEIFHKRDSTSIRIVTTPEQIVLEEARRNYTWLQLYNFNVDAVYMNKLYPKEAMNGYFEDWKKIQKDSIYLAEESFSEQKLFKLELQSEEIHGKEALEKIAKILYKNINPAEIFCQTESFKIEEVNGTRILTIHLPFAKEENIYVIKEKYDIIISLLNETRRFHLPDKLKTRKITDYFYKNGELKISMDYE
The following text describes a protein:
Function:
Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in mid-late stages of complex I assembly.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MIRRVLPHGMGRGRLTRRPGTRRGGFSLDWDGKVSEIKKKIKSILPGRSCDLLQDTSHLPPEHSDVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLSVGGICQQFSLPENIQLSLFSASFLRNINEYLAVVDAPPLDLQFNPSGYLLLASEKDAAAMESNVKVQRQEGAKVSLMSPDQLRNKFPWINTEGVALASYGMEDEGWFDPWCLLQGLRRKVQSLGVLFCQGEVTRFLSSSQRMLTTDDKAVVLKRIHEVHVKMDRSLEYQPVECAIVINAAGAWSSQIAALAGIGEGPPGTLQGTKLPVEPRKRDVYVWHCPQGPGLETPLVADTSGAYFRREGLGSNYLGGRSPTEQEEPDPANLEVDHDFFQDKVWPHLALRVPAFETLKVQSAWAGYYDYNTFDQNGVVGPHPLVVNMYFATGFSGHGLQQAPGVGRAVAEMVLKGRFQTINLSPFLFTRFYLGEKIQENNII
The following text describes a protein:
Function:
Serine/threonine-protein kinase which is part sphingolipid-mediated signaling pathway that is required for the internalization step of endocytosis by regulating eisosome assembly and organization, and modulating the organization of the plasma membrane. Phosphorylates and activates PKC1. Activates YPK1 and YPK2, 2 components of signaling cascade required for maintenance of cell wall integrity. Required for stress-induced P-body assembly and regulates global mRNA decay at the deadenylation step.
Subcellular Localization:
Nucleus. Cytoplasm, cell cortex. Note=Localizes at eisosomes, large, immobile complexes that mark sites of endocytosis near the plasma membrane.
Domain:
The PIF-pocket is a small lobe in the catalytic domain required by the enzyme for the binding to the hydrophobic motif of its substrates. It is an allosteric regulatory site that can accommodate small compounds acting as allosteric inhibitors.
Sequence:
MHKFRYSLHQHYSKRNSSDKSKDSPISQNSNEENDSTKLSSSSLQDLHDDLDDIYNNYTLAQGTNNNSVDTLDSENNQAINKFIDKPPAIHGMEPQLPVMHVSSRLSSLGNTTNETGESIAKSAPGTPLSSHSFDFRPHHPRAVTNSSLNVLLDTPNVSSEFNHLVDQTPPNESVERFDDSNNTVDNTEEEENNDDTDEIPKSETLKQNEENWEKKGAAVKTIKTMDGEMKTIRRNVTDFKFGKELGEGSYSTVILATDKITGKQYAVKVLDKRHIIKEKKVKYVNIEKHALNRLSNRLGVISLYFTFQDKDSLYFVLDYASNGELLTLIKRYNTLNEECTRHFGAQILDAIKYMHDNGVIHRDLKPENILLDDKMRIQITDFGTARLLEKKNDESEEYPVDVRAKSFVGTAEYVSPELLENKYCGKPGDVWAFGCIIYQMIAGKPPFKATNEYLTFQKITKLQFAFSAGFPTIIRDLIKKILVLQPSRRATIPEIQKHYFFQSVDFKDFDSIWLSDPPEIGPYKMTAKSMMKVPELNKAPITTVIKKNVKKSTNSNSNTNNVATAVGGSSSNGHKGSSPTPEKEPSPATINNKSTEKVSAASVAAYVLNKPATNQNSSTSEDSSKRSSNSNETRKLSYSQQDYIPGTNILRPQISTRPSVGSYVKTTPSKDRKTLTKVPSNIHQQQEKVKPKVMEVKPATTLEAAWEPYLTHPDERILRIGPVIAHKEPTEPFEKKNKASLHISPLDINKEQRSRSNTSLLTQIVNEVNNNTSELKKVENADESLAIIEPQYNMKRSPTSDSKKSMDIERSASTSGSRISKKAIFKKLGFSHLEKNDSEESNGPSLTEKPQTCTLVVTTHGRALLFIRNDIESNYLLIAEIKLKYPFIHFQELVISQTKFSKLVPSVGVFVISSIDNSLIFEVEKFEVNQWTEALAKSKYNEIGKR
The following text describes a protein:
Function:
Has a negative effect on cell proliferation.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MARVSSALNSLLILWLGVFLRVASAELRGPPKISEQVNGFRKAVQGRSIKLPCPVTGNPPPLIMWTKDGVTIHSGWERFRVRSEGLKVNDVVIEDSGSYICRATNGFGSVSVNFTLTITDGSSSPEEDPSRVDTPTVEERPDRPTSGTMPQFSELSKMMKAQKIMKPLNSSVRLKCKASGHPRPEIVWEKDGTRMVITEGRQSRQFTLKLSHLKPGDSGTYMCIVFNKHGRINATYEVDVVDQVKKKPELLGEHPVNTTVEFGGTTSFQCRVRSDIKPHIQWLKRVETHSTPTNATIEMDGQYFVVLPAGDVLPRPDGSYLNKLIISYATSDDAGMYICLGANTMGYSFKSAFLEVFPDPNMNWIDPALQQTPRVNPVVPEAWGHIEQGLLIGIPVSLALLFIVIVIICTISRKKARSQRRRHRTAPPAPQLPNSSIKKEYNHRDYLNRTNLTNPHMMDIEQCAPLTAAQCAPMTSQQTLHIYPVPSRENVLNRYDVHSPSSFTDTLNSNGSLTSSRPNMHHHLHQHTILHC
The following text describes a protein:
Function:
High affinity receptor for INSL5. Also acts as a receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MATSNSSASLPTLFWVNGSGDSVLSTDGAAMPVQFLVLRIMVALAYGLVGIIGLLGNLAVLWVLGNCGQRVPGLSSDTFVFSLALADLGLALTLPFWATESAMDFHWPFGSALCKVVLTTTVLSIYASTFLITALSIARYWVVAMAVGPGSHLSVFWARVVTLAVWVAAALVTVPTAIFGAEVELWGVCLCLLRFPSRYWLGAYQLQRVVLAFIVPLGVITTSYLLLLAFLERQQRCRPRQWQDSRVVARSVRVLVASFALCWVPNHVVTLWEILVRFDLVPWDSTFYTFHTYILPITTCLAHSNSCLNPVIYCLLRREPQQVLVSSFRALWSRLWPQRKACMEQMALKEVGGRTVASTQESGSSRTHTNTMEHLDEGCSLNTLLSETYQGQSPQILGRSSCSLSQAAVSPGEV
The following text describes a protein:
Function:
Involved in the biosynthesis of aklanonate which is an important precursor common to the formation of the clinically significant anthracyclines such as carminomycin, daunorubicin (daunomycin), rhodomycin, aclacinomycin T (aklavin) and aclacinomycin A (aclarubicin). These compounds are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers.
Sequence:
MAELSLAELREIMRQSLGEDEVPDLADADTVTFEDLGLDSLAVLETVNHIERTYGVKLPEEELAEIRTPHSMLIFVNERLRAAV
The following text describes a protein:
Function:
Required for the assembly of cytochrome c oxidase.
Miscellaneous:
MISCELLANEOUS: Present with 1360 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Mitochondrion intermembrane space.
Sequence:
MEKPSPTRRQTSSLSTISNGMTMTNDNRDTTNTNSGSTSSNNSQPSSSSTPPAASGPVTDRTKVNYVPKSDDPSSFQYYPDDPENPVNKYKFALKADSQYYDPCEESSKLSFQCLERNDYDRSKCQEYFDAYRECKKQWLTARRKNRQQWE
The following text describes a protein:
Function:
Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits. A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly complete Bam complexes show there is considerable movement of all 5 proteins.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Domain:
Contains two well-defined domains connected by a flexible linker. The C-terminal domain may serve as an important protein-binding surface for interaction with other Bam components or substrates. In addition, contains a long unstructured N-terminal region, which is required to stabilize the BamCD complex. Only the N-terminus of this protein is observed in the Bam complex in X-ray or EM structures, most of the protein must be highly mobile.
Sequence:
MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEAAPLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGDTASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGRYQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAANAAQNRASTTMDVQSAADDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNMAVTYKPLSDSDWQELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDALVAVFQAAFSK
The following text describes a protein:
Function:
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
Subcellular Localization:
Cytoplasm.
Sequence:
MAPTAAQIKSRARALGFHKVGIARADALDGEAAERLGGWLAAGYAGEMRWMHDPRRRDIQQVLPGVRSVICVALSYNTAQGEPAPGQARISRYALGRDYHKVLGKPLKELARWIEASDPGCRAVAYVDTGPVQEKAWAEAAGLGWIGKNACLITLEYGSWVFLGEILTTLDLEANDPHPNYCGTCTRCLSACPTAALVEPAVVDARKCLAYHTIENRAPELPEAIAEHQHGWVVGCDLCQTCCPFNLRAERWGRYSEVADFAPRDPWNEITLDQLADLSDAEFERWSEGSAIRRVKASGLRRNARSALGASGDSLAQAH
The following text describes a protein:
Function:
Fiber-like molecule that attaches the virion to the host cell membrane by binding to the primary receptor F11R/JAM-A and to sialic acid containing proteins (coreceptor). The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis (By similarity).
Subcellular Localization:
Virion. Note=Found in the outer capsid (36 copies).
Sequence:
MDASLITEIRKIVLQLSVSSNGSQSKEIEEIKKQVQVNVDDIRAANIKLDGLGRQIADISNSISTIESRLGEMDNRLVGISSQVTQLSNSVSQNTQSISSLGDRINAVEPRVDSLDTVTSNLTGRTSTLEADVGSLRTELAALTTRVTTEVTRLDGLINSGQNSIGELSTRLSNVETSMVTTAGRGLQKNGNTLNVIVGNGMWFNSSNQLQLDLSGQSKGVGFVGTGMVVKIDTNYFAYNSNGEITLVSQINELPSRVSTLESAKIDSVLPPLTVREASGVRTLSFGYDTSDFTIINSVLSLRSRLTLPTYRYPLELDTANNRVQVADRFGMRTGTWTGQLQYQHPQLSWRANVTLNLMKVDDWLVLSFSQMTTNSIMADGKFVINFVSGLSSGWQTGDTEPSSTIDPLSTTFAAVQFLNNGQRIDAFRIMGVSEWTDGELEIKNYGGTYTGHTQVYWAPWTIMYPCNVR
The following text describes a protein:
Function:
Probable serine protease.
Subcellular Localization:
Plastid, chloroplast thylakoid lumen.
Sequence:
MTMALASSKAFSSIFNTLSPINQSKFVLACSGSNHVDVIDRRRRIMIFGSSLALTSSLLGSNQQRLPMESAIALEQFKEKEEELEEEEERNVNLFQKTSPSVVYIEAIELPKTSSGDILTDEENGKIEGTGSGFVWDKLGHIVTNYHVIAKLATDQFGLQRCKVSLVDAKGTRFSKEGKIVGLDPDNDLAVLKIETEGRELNPVVLGTSNDLRVGQSCFAIGNPYGYENTLTIGVVSGLGREIPSPNGKSISEAIQTDADINSGNSGGPLLDSYGHTIGVNTATFTRKGSGMSSGVNFAIPIDTVVRTVPYLIVYGTAYRDRF
The following text describes a protein:
Function:
Involved in mitochondrial genome encoded proteins translation. Involved in the binding of tRNA to the ribosomes (By similarity).
Subcellular Localization:
Mitochondrion.
Sequence:
MSLFSPHRILLRTGSAFQLATATRALLSTSSQLRNTKNAQSGLAEQARAEEPVASSPSQTTRPEQKSLEEETTKQTQTHADSTVNEWGARLTDLNINARLPRSVQALYLRPLRRKAEYGLPVCDLQLRSYSVRNLEFFADFAIRAAYYLNLPVSGPVPLPKIVERWTFPRSSFVHKKSQENFERITVRRLIQIKDGNSQAVQAWLAFLRKHAFYGVGMKANIWEHESIEIAKTMDQTLPEIEKALEPHISQFGRREDAEPAHDLITNFLGSERLSLSKGPLTDVRGG
The following text describes a protein:
Function:
Probably involved in the control of the cell cycle.
Sequence:
MSTVNRLQCIGKLGEGTYGVVYKARELATGQIVAYKRIIVGSEDDGAPSTAIREIALLKVLRHNNIVRLYDVLFEPPKLTLIFEYCEYDLRRFMHKHDSRVRTQVKEILKQVLLGLRYMHQRSVVHRDLKPDNIFVRVDGISGSEGSEMSVSSRETEVVNTRGHWDDIDEAANCPKNANPTENPNARIASEDHGADGTVPSGSTTPTSQLVIKLGDYGMARIESIPVKKYSHDVASLWYRSPDALLGSAMYGFAVDLWSVGCIFAEMVTGAPLIRGNTDVDQLLKTFKLLGTPTPETWPSMKNCPKAVQLLKAAAELARGEPAENGKKTKNSRGVHKQHERNLPNVQKTATGTSHLSAVMRVGIDGESGCVADPRDELYHFPPELCFPSAFDEYVKASGFQGRVGVEGTDFLRRLIRYEPSQRMSVQEALSHPFVSNTVALMQRPLDVMASMLRQSLREHSVYP
The following text describes a protein:
Function:
Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes (By similarity).
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Synapse. Presynaptic cell membrane; Peripheral membrane protein.
Sequence:
MSAPLGPRGRPAPTPAASQPPPQPEMPDLSHLTEEERKIIQAVMDRQKKEEEKEQSVLKKLHQQFEMYKEQVKKMGEESQQQQEQKGDAPTCGICHKTKFADGCGHNCSYCQTKFCARCGGRVSLRSNKVMWVCNLCRKQQEILTKSGAWFYNSGSNTPQQPDQKALRGLRSEEAPQEKKAKLHEQTQFQGPPGDSSVPAVERGRAHGLTRQDSIKNGSGMKHQIASDMPSDRKRSPSVSRDQNRRYDQSEEREEYSQYVPSDSTMPRSPSDYADRRSQREPQFYEEPDHLNYRDSNRRGHRHSKEYIVDDEDVESRDEYERQRREEEYQARYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANAELEDSRISLLRMDRPSRQRSVSERRAAMENQRSYSMERTREAQGQSSYPQRTTNHSPPTPRRSPIPLDRPELRRADSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPRPHKSKKGGKMRQVSLSSSEEELASTPEYTSCDDVEIESESVGEKGDMEYSWLEHASWHSSEASPMSLHPVTWQPSKDGDRLIGRILLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDMPRIPDSTHAQLESSSSSFESQKMDRPSISVTSPMSPGMLRDVPQFLSGQLSSQSLSRRTTPFVPRVQIKLWFDKVGHQLIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQLHGESPTRRLQRSKRISDSEVSDYDCEDGVGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCSPSGSPHRVDVIGRTRSWSPSVPPPQRNVEQGLRGTRATGHYNTISRMDRHRVMDDHYSSERDSHFLTLPRSRHRQTSEHHHRDGRDCEAADRQPYHRSRSTEQRPLLERTTTRSRSSERADTNLMRSMPSLMTGRSAPPSPALSRSHPRTGSVQTSPSSTPVTGRRGRQLPQLPPKGTLERMITEDMDSTRKRNSGAMDIEERNRQMKLNKYKQVAGSDPRLEQDYHSKYRSGWDPHRGADTVSTKSSDSDVSDVSAVSRTSSASRFSSTSYMSVQSERPRGNRKISVFTSKMQSRQMGVSGKSMAKSTSISGDMCSLEKNDGSQSDTAVGALGTSGKKRRSSIGAKMVAIVGLSRKSRSASQLSQTEGGGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
The following text describes a protein:
Function:
By binding to host chemokine CX3CL1, mediates the cytoadherence of host erythrocytes infected with parasite mature forms (late trophozoite and schizont) to endothelial cells, which sequesters them away from the circulation and thus prevents their elimination by the host spleen.
Subcellular Localization:
Host cell membrane; Multi-pass membrane protein. Host cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=At the ring and trophozoite stages, localizes to Maurer's clefts. Localizes to the cell membrane of host erythrocyte infected with parasite mature forms (late trophozoite and schizont). In gametocytes, localizes to the host erythrocyte cytoplasm; export to the host cytoplasm begins after stage I.
Domain:
The P.falciparum Export Element (PEXEL) motif, also known as the vacuolar transport signal (VTS), is a pentameric sequence (RxLxE/Q/D) required for the translocation of proteins across the parasitophorous vacuole membrane (Probable). In the endoplasmic reticulum, the motif is cleaved after the leucine residue and the N-terminus is N-acetylated.
Sequence:
MNIYIRTIFFAPFICLLIFSSNHGLFQKKDNQNCNSHKFCLNCSGSYLKNSRWLSETSVSYSDEGEPLKYGANDNNYDSNLLKSEEQKQEISEHMKMLIKLYIDSSHDSAKEEKLFQQVKKYFKNNEYKDFMRTFIKVIKIHNDLTHLKKQMASTEKRYRIISCVAAFLSTVSLAFTVVMLSTLNLKNENVIVTIILGLLGFIISLPVISYILSPYLNSSLEKGYRIADLYSEKILRQILHFQ
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Domain:
The homeodomain differs form the typical one by having namely 4 instead of 3 extra amino acids inserted in the loop between helix 1 and helix 2.
Sequence:
MEAVVGVKYRPVVFPNGGAAAAAAGKSKATPASATAAVYRECLKNHAASLGGHAVDGCGEFMPSPAADAADPASLKCAACGCHRNFHRRLPEAPPSPPLLALPPPPPPPPPPPPPPQPQQHLPRTAAVAVAPQLLLHGSHQRREQSPETDRVRGPGHHHDDDAAADDDDSEDSEMSDYDDDRSASPLQAPPPVLSPGYLPSATHMLLSLGSASAPAVAASRPHAAAAAMGPPPPPGAATSASRKRFRTKFSPEQKQRMQALSERLGWRLQKRDEAVVDECCREIGVGKGVFKVWMHNNKHNFLGGHSARRSAAAAAAAPLAPPPVLTDFSINGSSTHAAAADHAAATASGGGGGSPQST
The following text describes a protein:
Function:
Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.
Sequence:
MTPVIIKNIECFITRPDRHNLVTVRVTTDQGVTGHGCATFQQRPLAVKTLVEEYLQPLLTGRDANNIEDLWQMMNVNAYWRNGPVMNNAISGVDMALWDIKSQLAGMPLYQLFGGKSRDAIPAYSHASGDTLDALFASVDALIEKGYRHIRCQLGFYGGTASGLHAPENPTPGAWFDQQEYMSNTVDMFRALREKYGWKLHILHDVHERLFPQQAIQLAKQLEPYQPYFIEDILPPQQSAWLEQVRQHSCVPLAMGELFNNPSEWHDLIVNRRIDFIRCHVSQIGGITPALKLAHLCQAFGVRLAWHGPGDMTPVGVAVNTHLNIHLHNAAIQEFIPRSAMTDKIFPGAPEVKDGFIYPPVNAGIGVGFNEELARAHPVMYRPHEWTQSRLPDGTLHTP
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Independently of its E3 ubiquitin-protein ligase activity, acts as an inhibitor of CPSF3 endonuclease activity by blocking CPSF3 active site.
Sequence:
MNDGTESEDSSYFMEVYDRIHAVDLVLRGSDHPDSIEISPSKIQTKKGDGTVETYPLVVNIEPTSCTSIQKHMNEGIGMRLQLRDSNPEPQTSLLSTTVKRVSNEISRLERGSSQCGCKTCGLTLFVKNVKFNRVLPLPSQSWRDLFNNWSCCSHSHKQKESNKEKVTTPAFVTNGVLKPRENDCLISDFHIMVHTKTVERKNILLRKLDYLPKEGALTSREMKCSRCRAVLGEAVGYEKSTIEAYKLNKNSIEVLSLRKHLSETFVRPVFFSEFFLERILAQQLSNAVDVHATHMFIVQDLNEKVHVLIRVMNTSTRLYVNNGKSVNEITESTREFCSISTNARIQSSNVKMKKGKSTTENSGVCHHGNGDGHASHSKGRQSRQFTEITEESDQVENDRIRRDGPPCMQGNKVAEVIEKLFSFSTHLISIGRTCNEIREADPTGCERIVKVMYASTDNPKMKQQTAKWLKDERTLTLTYPHEICVQMLLVLVSSTLTMPVAYRVFGDFVVGFLRLD
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin RelE3, but no other RelE or ParE toxin.
Sequence:
MSGVIAPDRVDDKRRMEHSQNMALTITIPAELASRLRASAEAEGKDVDAYAIDALHVMSDEDWGYTDDDAYWRELRAHSDEVRRDGGIPLEDVKRWVASWDTENELPPPEPRIKARG
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MLQQVGVIPVLPEPGPTTISAPRHTAADARGAPETESYNRAVQRLKDGSGKGSATEADARCGCSRATSRWCRSYANFSADSAESYGNMMKNKVLGTDGSDGDMPAAQMPAFAYLHLNHDYGDDDKMFFCDDDQRLVMRTDTYIVPSLFLVTTFQDELDALFPERGAVFHYLGRYLFPQANHTAVLQRVPRAGVAAAGRRPGARLRPPARRSRRTSSSSSSSRARGRRSCYRR