lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Domain:
The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.
Sequence:
MQQPQQQDLQIGLPYAPVQPPIPSPAAYFAYLPSPSRWTFTQGLIVGQVSMVIVALLLIRYVIFEDSATALEKERLMRLKVSQRRSKLHAKALLQDARKANSAAASAAAAAAPSPASHPLRKSHRLASDTRASMFANILDKTAYDLSSHLPESADWLNVMFAQAIAGYREDVLTGGVSSHHHTASDAIPSPNPLEPQKERTARDLMEEILNRATSSFLDPIRVTEADFGDAYPIFTNARVRPADDTGRTRIEIDVDYSDQITLAIDTKLLINFPKPRFAVLPVSLGLTIVRFSGTLAIELFSSDPNATVLPTANPNPSSSSSSSATPPRSRHQLHFSLHPDFALEASATSLLGSRAKLQDIPKIEQLLISRLRGWIMDRFVWPRYWSLTLPNLVPSPAASRSFSAAAAANRHTDAASVGSSGGHGQINVGTGVERTDASVIQPGHHESARQEMLHAASERPSLASSRPPHVRSSSSGLRANGMGSVEAWRAHAAGVYNQPSHQHATSLNQAALLRAHVGGGGATDCAPGSDVNIEVPGSYRGSVAGAGIELASSSNASSVLPTGAHHSSGLRNRPGFVQ
The following text describes a protein:
Function:
Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.
Miscellaneous:
MISCELLANEOUS: Present with 876 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNEDLPKEYFELIRKALNEKEAEKAPLSRRRRVRRKNQPLPDAKKKFKTGLNELPRESVVTVNLDSSDDGVVTVPTDDSVEEIQSSEEDYDSEEFEDVTDGNEVAGVEDISVEIKPSSKRNSDARRTSRNVCSNEERKRRKYFHMLYLVCLMVHGFIRNEWINSKRLSRKLSNLVPEKVFELLHPQKDEELPLRSTRKLLDGLKKCMELWQKHWKITKKYDNVGLYMRTWKEIEMSANNKRKFKTLKRSDFLRAVSKGHGDPDISVQGFVAMLRACNVNARLIMSCQPPDFTNMKIDTSLNGNNAYKDMVKYPIFWCEVWDKFSKKWITVDPVNLKTIEQVRLHSKLAPKGVACCERNMLRYVIAYDRKYGCRDVTRRYAQWMNSKVRKRRITKDDFGEKWFRKVITALHHRKRTKIDDYEDQYFFQRDESEGIPDSVQDLKNHPYYVLEQDIKQTQIVKPGCKECGYLKVHGKVGKVLKVYAKRDIADLKSARQWYMNGRILKTGSRCKKVIKRTVGRPKGEAEEEDERLYSFEDTELYIPPLASASGEITKNTFGNIEVFAPTMIPGNCCLVENPVAIKAARFLGVEFAPAVTSFKFERGSTVKPVLSGIVVAKWLREAIETAIDGIEFIQEDDNRKEHLLGALESWNTLLLKLRIRSKLNSTYGKIAEEEPNVTKEQNIADNHDNTETFMGGGFLPGIANHEARPYSEPSEPEDSLDYVSVDKAEESATDDDVGEDYSDFMKELEMSEESD
The following text describes a protein:
Function:
Intake of glucose and galactose.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MFFSLGFALGINSVLVPVLKGSLEISSAESYLIIAATFIPFLIFGYPAGLTIKKIGYKRTMVLSFLMFAIAFGLFIPSASYESFPLFLLASFISGSANAYLQAAVNPYITILGPIDSAAKRISIMGICNKLAWPIPPLFLAFLIGKEVTDITVADLFLPFYVIIAAFIALGIIAYMAPLPEVKAVGEDDSEEAAEACPYAAKKTSIWQFPHLLLGCLALFLYVGVETVSLGTLVDYATSLHLENAAMYAWIAPIGIVIGYICGIIFIPKYMSQATALKICSVLAIIGSVLVVLTPADISIYFISFMALGCSLMWPALWPLAMADLGKFTKSGSSLLIMAMAGGAVIPTLFGYLKDISDIQKAYWICLPCFLFILYYGVAGYKIRTK
The following text describes a protein:
Function:
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
Sequence:
MSRVIHISSNEELDKHLQAERLVIDFSAAWCGPCRAISPVFEKLSNEFVTFTFVHVDIDKLSGHPIVKEIRSVPTFYFYRNGAKVSEF
The following text describes a protein:
Function:
Controls the rotational direction of flagella during chemotaxis.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MAEEQENTAQQPPKKSKALLFVIIGSVLVMLLLVGVIIMLLMGNKEESKENASKNTQEVQANPMANKNQEAKEGSNIQQYLVLGPLYAIDAPFAVNLVSQNGRRYLKASISLELSNEKLLNEVKVKDTAIKDTIIEILSSKSVEEVVTNKGKNKLKDEIKSHLNSFLIDGFIKNVFFTDFIIQ
The following text describes a protein:
Function:
Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.
Subcellular Localization:
Nucleus.
Sequence:
MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKSQVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQAEMQSSASSKDSSQSKIIRFTLGQKKISRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEESWEKSSVDNFVSRLHSSLHFSLPLFHHARYELVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL
The following text describes a protein:
Function:
TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Core scaffold of the TFIID complex. Acts as a histone acetyltransferase involved in the light regulation of growth and gene expression. Required for H3K9, H3K27, and H4K12 acetylation on the target promoters.
Subcellular Localization:
Nucleus.
Sequence:
MICRVDYGSNDEEYDGPELQVVTEEDHLLPKREYLSAAFALSGLNSRASVFDDEDYDEQGGQEKEHVPVEKSFDSEEREPVVLKEEKPVKHEKEASILGNKNQMDTGDVQEELVVGLSEATLDEKRVTPLPTLYLEDDGMVILQFSEIFAIQEPQKKRQKREIRCITYRDKYISMDISELIEDDEEVLLKSHGRIDTHGKKTDQIQLDVPLPIRERSQLVKSGIVRDTTSESREFTKLGRDSCIMGELLKQDLKDDNSSLCQSQLTMEVFPLDQQEWEHLILWEISPQFSANCCEGFKSGLESAGIMVQVRASNSVTEQESLNVMNSGGQTQGDNNNMLEPFFVNPLESFGSRGSQSTNESTNKSRHHPQLLRLESQWDEDHYRENGDAGRENLKQLNSDARGRLSGLALQDRDMWDESWLDSIIWESDKDLSRSKLIFDLQDEQMIFEVPNNKERKYLQLHAGSRIVSRSSKSKDGSFQEGCGSNSGWQFNISNDKFYMNGKSAQKLQGNAKKSTVHSLRVFHSAPAIKLQTMKIKLSNKERANFHRPKALWYPHDNELAIKQQKILPTQGSMTIVVKSLGGKGSLLTVGREESVSSLKAKASRKLDFKETEAVKMFYMGKELEDEKSLAEQNVQPNSLVHLLRTKVHLWPWAQKLPGENKSLRPPGAFKKKSDLSNQDGHVFLMEYCEERPLMLSNAGMGANLCTYYQKSSPEDQHGNLLRNQSDTLGSVIILEHGNKSPFLGEVHGGCSQSSVETNMYKAPVFPHRLQSTDYLLVRSAKGKLSLRRINKIVAVGQQEPRMEIMSPASKNLHAYLVNRMMAYVYREFKHRDRIAADELSFSFSNISDATVRKYMQVCSDLERDANGKACWSKKRKFDKIPLGLNTLVAPEDVCSYESMLAGLFRLKHLGITRFTLPASISTALAQLPDERIAAASHIARELQITPWNLSSSFVTCATQGRENIERLEITGVGDPSGRGLGFSYVRVAPKSSAASEHKKKKAAACRGVPTVTGTDADPRRLSMEAAREVLLKFNVPDEIIAKQTQRHRTAMIRKISSEQAASGGKVGPTTVGMFSRSQRMSFLQLQQQAREMCHEIWDRQRLSLSACDDDGNESENEANSDLDSFVGDLEDLLDAEDGGEGEESNKSMNEKLDGVKGLKMRRWPSQVEKDEEIEDEAAEYVELCRLLMQDENDKKKKKLKDVGEGIGSFPPPRSNFEPFIDKKYIATEPDASFLIVNESTVKHTKNVDKATSKSPKDKQVKEIGTPICQMKKILKENQKVFMGKKTARANFVCGACGQHGHMKTNKHCPKYRRNTESQPESMDMKKSTGKPSSSDLSGEVWLTPIDNKKPAPKSATKISVNEATKVGDSTSKTPGSSDVAAVSEIDSGTKLTSRKLKISSKAKPKASKVESDSPFHSLMPAYSRERGESELHNPSVSGQLLPSTETDQAASSRYTTSVPQPSLSIDKDQAESCRPHRVIWPPTGKEHSQKKLVIKRLKEITDHDSGSLEETPQFESRKTKRMAELADFQRQQRLRLSENFLDWGPKDDRKWRKEQDISTELHREGKVRRAYDDSTVSEERSEIAESRRYREVIRSEREEEKRRKAKQKKKLQRGILENYPPRRNDGISSESGQNINSLCVSDFERNRTEYAPQPKRRKKGQVGLANILESIVDTLRVKEVNVSYLFLKPVTKKEAPNYLEIVKCPMDLSTIRDKVRRMEYRDRQQFRHDVWQIKFNAHLYNDGRNLSIPPLADELLVKCDRLLDEYRDELKEAEKGIVDSSDSLR
The following text describes a protein:
Function:
Probable ATP-dependent zinc metallopeptidase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MASLCPLSAAPAFPRAARPRAASFRGPASWSGLAATASNACVCSCGLLPTGGYARLRSRLRSPVRAKIDEADKGTGAGLGFPSPRRRKLRLRLRPRLRLLWWRLRRLSPRELMTDAGAALRRAVRRVPPAAAAPVVLALLLAVARLALPKNVAREVAYSDLVAGLREGAVAAVAFEEDSRRIYFSKNAGDDVGSDTNETGENAAAPAPKWPYYARRVPHDEGFLLGLMRDGRVDYRSSPRPAGRLLVDMLSTLLTLWVSLVPVMWFIQRQMSGAGGADKRRKPRKQRVGFDDVQGIDEAKEELVEIVSCLHGSLNYKKLGAKLPRGVLLVGPPGTGKTLLARAVAGEAGIPFFSVSASEFVEVFVGRGAARVRDLFKEAKEAAPSIIFIDELDAVGGSRGRSFNDERDQTLNQLLTEMDGFDSDMKVIVMAATNRPKALDAALCRPGRFSRKVVVGMPDVEGRKKILDVHLRNIPLEEDHGIISDLVARVTPGLVGADLANIVNESALLAARRGRNTVSREDIMDAIEREKYGVTGRQEADSERQGLTKLFPWLSKPGNKPSSPDDFRGLMGYHTLS
The following text describes a protein:
Function:
Multidrug resistance pump that participates in a low energy shock adaptive response.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKRQRNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGAVQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVGMSIFMLATLVAVTTSSLTVLIAASAMQGMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWNWRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTLFGNSGFNCYLLMLIGGLAGIAAFEACSGVLMGAVLGLSSMTVSILFILPIPAAFFGAWFAGRPNKRFSTLMWQSVICCLLAGLLMWIPDWFGVMNVWTLLVPAALFFFGAGMLFPLATSGAMEPFPFLAGTAGALVGGLQNIGSGVLASLSAMLPQTGQGSLGLLMTLMGLLIVLCWLPLATRMSHQGQPV
The following text describes a protein:
Function:
Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
Subcellular Localization:
Cleavage furrow. Cytoplasm, cytoskeleton. Midbody.
Sequence:
MALVTLQRSPTPSAASSSASNSELEAGSDEDRKLNLSLSESFFMVKGAALFLQQGNSPQGQRSLQHPHKHAGDLPQHLQVMINLLRCEDRIKLAVRLESVWTDRVRYMVVVYTSGRQDTEENILLGVDFSSKESKSCTIGMVLRLWSDTKIHLDGDGSALQVLHKACEVARRHNYFPGGVALIWATYYESCISSEQSCINEWNAMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTSKEIRNELEKQMNCNLKEFKEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYQFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAFNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQPADDTIAEPSEFLPETLDGALDTQLPCLEDATHPGLPRSLPSGGPSLPCCFRRLSDPLLLPHRDGAGGLVHLEDLERDALLEDEAQPVEVRKLVPSSQEGDRLCEKDVKRKLEFGSPKARSGSLPQVEELEKDGSPRPGRWRRASTQLERGLLDQENLNNNNSKRSCPDDFERDAVFGILSKVKPPYTSCADCMYPAAGAPEAFMERHEDPSSSAICTQPTFLPHVTSSPMAHTSNRSRAPERPTSGPANTSPFLLPAGSRKPDVSGSGAGVAPEPPASLPEPSRETSKALQKSLLSKNSHCDKNAANTEAAAKEELSTKKDPKPSKDLRLLFSQEGEKPTANSYLMQHQESIIQLQKAGLVRKHTKELERLKSLPSDSPSTCRDSAASRLEASIPEEGQEPAHPALDSQAGTEEKPVGGASQKSPPPTLLLRLDHTSKDFSKDFLKSACYTPTPSSISSNLTRSSSSDSIHSVRGKPGLVKQRAQEIETRLRLAGLTVSSPLKRSHSLAKLGSLNFSTEDLSSEADTSTIADSQDAKCTLSSFLPEPQAAPRNPSATSKPSGKSAPENLKIPVRVNKS
The following text describes a protein:
Function:
May be involved in recombinational repair of damaged DNA.
Sequence:
MLIGLSIRDVVLIESLDLAIGEGLTALTGETGAGKSIILDALGLATGARADAGLVRRGATGHASATAIFALPADHPAFAYLDDKGLSYARDEDVVLRRQLSPDGRSRAFVNDQATSVGVLKDLGALLLEVHGQHETVGLLDPKTHRGLLDTFGGVSLGAVASAWSAWRAARDRAEALRDLAGRAAAETEELTLRLSELDRLDPREGEEASLAEERALLSSAEKAMADIAAAQDALAGDNLSGRLAQAYRALERARDRALQAGAPAEGSAMTRLSAACEAVDRALVEAQEASAAIDAVAETFEFEPDRLEKAEERLFALRGMARKLNVLVDDLPAKRAEFAARLQAIETSEDSLRAAEKDAAEAREAYLYAAEALSAERRAAGDALAKAVEAELTPLKLEKARFRVAVEPLGEDRAGPSGLDRVAFEISTNPGAPFGAMEAIASGGELARFALALKAALAGRGGGPQPLMIFDEVDQGVGGAVADAVGLRLKRLAANAQVLVVTHSAQVAARGDAHWRISKSGDDTSTRTRVEPLSPAQREEEIARMLSGAEVTEAARAAARALLTLHA
The following text describes a protein:
Function:
FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheX chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein. Bacterial flagellum basal body.
Sequence:
MSDVLSQEEINQLIEALMKGELKEEDLLKEEEEKKVKPYDFKRPSKFSKEQLRTFQMIHENFGRALSTYLSGRLRTFVDVEISIDQLTYEEFIRSVMIPSFIVIFTGDVFEGSAIFEMRLDLFYTMLDIIMGGPGENPPNRPPTEIETSIMRKEVTNMLTLLAQAWSDFQYFIPSIENVETNPQFVQIVPPNEIVLLVTASVSWGEFTSFINVCWPFSLLEPLLEKLSDRFWMMGRKPEKVEERMEELRKASQKIPVTVQAVIGETELRLKEILDLEVGDVIRLGTHYKDEIRIDVEGRPKFRGIPGVFKGKYAVKVTGEFTNGGEYE
The following text describes a protein:
Function:
Transcription factor. Binds to the consensus 5'-TGATNNAT(G/T)(G/A)-3' PBC/Hox motif of target genes to regulate gene expression; sem-2 in order to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage), and egl-18 and elt-6 to regulate vulval development. May bind to the PBC/Hox motif as a heterodimer with homeobox protein ceh-20. Regulates vulval precursor cell (VPC) differentiation, in concert with orphan nuclear receptor nhr-25. Regulates the expression of mig-13, which controls the asymmetric distribution of actin cytoskeleton-binding protein cor-1 in Q neuroblasts. This in turn controls the polarity of migration of Q neuroblasts and the subsequent mid-body region-specific development.
Subcellular Localization:
Nucleus.
Sequence:
MTTSTSPSSTDAPRATAPESSSSSSSSSSSSSSTSSVGASGIPSSSELSSTIGYDPMTASAALSAHFGSYYDPTSSSQIASYFASSQGLGGPQYPILGDQSLCYNPSVTSTHHDWKHLEGDDDDDKDDDKKGISGDDDDMDKNSGGAVYPWMTRVHSTTGGSRGEKRQRTAYTRNQVLELEKEFHTHKYLTRKRRIEVAHSLMLTERQVKIWFQNRRMKHKKENKDKPMTPPMMPFGANLPFGPFRFPLFNQF
The following text describes a protein:
Function:
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity). Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking. Regulates cell shape and elongation in aerial organs (i.e. cotyledons, leaves, and hypocotyls) probably by regulating cortical microtubules (MT) arrays orientation. May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell membrane. Note=Recruits calmodulin (CaM2) to microtubules.
Sequence:
MAKKNGTSWFTAVKKILWSPSKDSDKKTHHHKETDIKRKEKKGWIFRKTKLETTNSVLQHTVRTVEAEEKEKPPVIVSSVEEGVTEIVKLTATPGFIRRHWAAIIIQTAFRGYLSRRALRALKGIVKLQALVRGNNVRNQAKLTLRCIKALVRVQDQVLNHHQQQRSRVLLSPPSRNYNIEARRNSMFAESNGFWDTKTYLQDIRSRRSLSRDMNRCNNEFYSEETELILQKKLEIAIKREKAQALALSNQIRSRSSRNQSAGDDRELLERTQWLDRWMATKQWDDTITNSTNVRDPIKTLEAVTTHHHQRSYPATPPSCRASRSVMVRSASPRIPCSPSSMQPNYMSATESAKAKARTQSTPRRRPMTAKKRLCYAEEESLRSPSFKSCLWGDHESDYSCCYGDGFAGKISPCSTTELRWLK
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. ChpB is a sequence-specific mRNA and (weak) tmRNA endoribonuclease that inhibits protein synthesis and induces bacterial stasis. Cleavage is independent of the ribosome. Cleavage occurs at ACY sequences where Y is not C. The endoribonuclease activity is not as strong as that of MazF. The endoribonuclease activity (a toxin) is inhibited by its labile cognate antitoxin ChpS. Toxicity results when the levels of ChpS decrease in the cell, leading to mRNA degradation. Both ChpS and ChpB probably bind to the promoter region of the chpS-chpB operon to autoregulate their synthesis.
Sequence:
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLVNQVRMMDLHARLAKRIGLAADEVVEEALLRLQAVVE
The following text describes a protein:
Function:
Converts proline to delta-1-pyrroline-5-carboxylate.
Sequence:
MSLVPKRPGIVSLLAGKQLRCQVSTLNTTPPTHRPQDAIISQPSPSSKKAPLSVLPTGALIRSLLFTSIMSSPLLNPCLAIMKYVVDSNSPLLNPSKNPLIDYLLRKTIYNHFCAGTNEDEVRKTVQDMKSLGFKGVILGYARESIAKADENDNSSFHAEKSQLAIQDQAVEEWRQGNLRTLKMIGAGDFLGIKFTGAGPKAVAALSQGDLVPPPSIAQAIDEICEATASQNSRLWIDAEQQVFQPAIDAWTIDLMRRFNRNGQIVVYNTIQAYLKSSSENVHRHLCLAQKQGWTLGIKLVRGAYIAHDIRSRIHDTKADTDNSYDHIVESLLSRKFPLKVAADNAAAFPDVRLFVASHNAESVRKASALYRQRINNGQPTIPLEIGQLQGMADEVSCELLAGNSTGQSEMPTPGVFKCLAWGTTEECLHFLLRRAIENKSALERTKDTAVAMRREAWRRLWW
The following text describes a protein:
Function:
Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.
Sequence:
MEFHEQKILPAVRQIKDLEKLLHSSYEYIVILDIHVGQLKSVISLAKQYCKKVFLHVDLIHGLQSDGHATEYLCQEFRPYGLLSTKASVIMKAKQKGVVAIQRIFLIDSSAMEKSCNLLDKTKPDYIEVLPGALTDVIAEVKERTGVPILAGGFIRTVEDVERALNAGATAITTSKRELWKHYQKK
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin Rv0298/MT0312.
Sequence:
MIAPGDIAPRRDSEHELYVAVLSNALHRAADTGRVITCPFIPGRVPEDLLAMVVAVEQPNGTLLPELVQWLHVAALGAPLGNAGVAALREAASVVTALLC
The following text describes a protein:
Function:
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Modulates plant growth and development.
Subcellular Localization:
Cytoplasm.
Sequence:
MAETDKNIEIWKVKKLIRALEEARGNGTSMISLIMPPRDQVSRVTKMLGDEYGTASNIKSRVNRQSVLGAITSAQQRLKLYNKVPPNGLVLYTGTIVTEDGKEKKVTIDFEPFKPINASLYLCDNKFHTEALNELLESDDKFGFIVMDGNGTLFGTLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKTAELATQFFINPATSQPNVAGLILAGSADFKTELSQSDMFDQRLQAKILNVVDVSYGGENGFNQAIELSAEILSNVKFIQEKKLIGKYFEEISQDTGKYVFGVEDTLKALEMGAVETLIVWENLDINRYVLKHSTSGETIIKHLRKDQETDQNNFLDSATSAELEVQEKISLLEWFANEYKRFGCTLEFVTNKSQEGSQFCRGFGGIGGILRYQLDLRAFDELSDEEFEEDSE
The following text describes a protein:
Function:
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MFKLVSYIILSWVLVCLAQPDVSVVASVVSCICGYSLLWAGLFALVEQLSWKKVWCIAFIWTWTVEGAHFSWMLEDLYVGTSIYFVWGILLSYLATLFASFSCLVVWCCRKQYRGALVWLPGVWVAIEAIRYYGLLSGVSFDFIGWPLTATAYGRQFGSFFGWAGQSFLVIAANICCFAVCLLKHSFSKGLWLTLCAFPYLLGGAHYEYLKKHFSDSEVLRVAIVQPGYSPHMHAGRTASAIWRGLVSLCQTIQTPVDVIVFPEVSVPFGLHRQAYTLHENQPVLESLLPNKSWGEFFTNLDWIQAIAERYQCTVIMGMERWENKGGILHLYNAAECVSREGEITSYDKRILVPGGEYIPGGKIGFSLCQTFFPEFALPFQRLPGEFSGVVNITERIKAGISICYEETFGYAIRPYKRQQADILVNLTNDGWYPRSRLPLVHFYHGMLRNQELGIPCIRACRTGVSAAVDSLGRIVGILPWESRTCPVSTGVLQVSVPLYSYHTVYARLGDAPLLLIAVCSVIGAIAYFYRKKKETPPQTFF
The following text describes a protein:
Function:
May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).
Sequence:
MSDVQTPFQLLVDIDQRCRRLAAGLPAQQEAVQSWSGIGFRMGGRFFVAPMGEVGEVLHEPRYTQLPGVKTWVKGVANVRGRLLPIMDLCGFLGTELSPLRKQRRVLVVEHLDVFAGLIVDEVFGMQHFPVDTFSEQLPPLEAALQPFIHGVFHREQPWLVFSPHALAQHQGFLDVAV
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MIIKKKESFKSPGRLWRVTKIRKLTAAKKNELQNRKCNQASNEEKKILYKSNFLDRFIPSKANSDAFRIMENAFTEKLNTQESLLPDILNLNVKGVLHYKDNKKQKTTRLIESTNYQRQTIHGASSSLVIEVEENGHLSNMQGSLYETPLRILDAPGLLDDFYISPLAWSTNGELAVALAQNVYLWSEISGPSIMELSPTTYEVSSLAYSSDGGFLAIARVNGFVEIWNRKTKNNRCDYKFHHDGDISCMAWSPINWTLLVGGSTGNIYVYRRTKSMMRRVHTIKKVHQEQVCGLEWNYDGTQFASGGNDNLVCIFDIDSLENKKFYWIHLAAVKALAFCPWQKSLLAVGTGSNDQQIYFYDTFRGHRIHSLFCGAQVTSVIWSRRYKEFCYSLGYSPEGTNSSLIVYRWPQLTKVFDIPSAAIDGWGQDLRTIMAIHTHRKYSNNTWEEGEYVVVANSDETVKFYKIWGNEMQEIHNDRVLYREGIFGSHILEMLENIPEQVLTNGVR
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MKRFSFSDSSGKLLYPPEEKNTENLAYSTDFQAMLDGLEDEDGIEESGCVTGKKRRLRVDQVQALEKIFEVDNKLDPERKVKIAQELGLQPRQVAIWFQNRRARWKTKQLERDYNILKANYEALQLNYTKVEQEKEGLINQLKGLKEKIGEENSTAFQRPQEILELNPRNYEVSNKLNSDFVDSKDGSSDSDSSGVMNEENYNNTLNYQPLMPKVSSYNALDHLSLSSSTYTQLLDPRASSTSSMRGYNQQQQQVGKMEEQNGFTTEDSCNIYSVDQAPNLYWYLSDHRN
The following text describes a protein:
Function:
Permease for high affinity iron uptake.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAKDVFSVAIFFIVLRETLEASIIVSVLMSFISQTLMDKDGNVTDPKLKRKFMLQVWIGSFTALFICLAIGGGFIGAFYALDKDIWSGSEEIWEGVFSLIAVVLITVMGFAMLRVSHLQEKWRKKLMKSIANRKAKGISNWGKKYSMFLLPFFTVLREGLEVVVFVGGVGLETPATAFPLPVICGLIVGCLIGYFIYRGGNVMNLQWFLIASTCILYLISAGLMSKATFYFEMNKWNHQTGGDAGELGDGPGSYPFKSAVWHVNYGNPEMNSNGGYMIFNAILGWNNTGTYGSILSYIIYWLFVAFIMFLMWYKERRAARLLIAKLGDKVVDLEAASSHTPVQSSSSEDEFKINSPTDDKGDKAIDIVTEVRESSSPVEEHKDDKTVDVINEIRESH
The following text describes a protein:
Function:
Activates SnRK1.1/KIN10 and SnRK1.2/KIN11 by phosphorylation of their activation-loop 'Thr-198' and 'Thr-176', respectively. Required for the regulation by SnRK1 kinases of the transcription of a large set of genes, the modification the activity of metabolic enzymes, and the control of various nutrient-responsive cellular developmental processes.
Sequence:
DGSKMINQYVRHERIGKGSYGKVVLHRSLFDQKFYAIKVFDKSRLGKIRVAPSETAMMDVRREVKVMKHLRHPNIVRLIEVIDDPECDQLYMVLEYIEGQRMFKQSGPPGGLGESTARRYFRDIVAGLMYLHNNKVIHGDIKPENLMITAEGRIKIGDFGISRTFEGDDDLLRRSPGTPVFTAPECCKGISRMAYHGKAADVWALGVTLYCMVTGQYPFVGENFQDTYDKIVQQELSVPPGLDPDLQNLLEGLLCKDPDQRMTLDAASCHPWLLKASS
The following text describes a protein:
Function:
Probably acts as an adapter for ATPase cdc-48.1 and/or cdc-48.2, conferring substrate specificity. May play a role in the ER-associated protein degradation pathway (ERAD) possibly acting as a platform to recruit both ubql-1 and cdc-48.1 and/or cdc-48.2 to the ER during ERAD.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Both the N- and the C-terminus face the cytosol.
Domain:
The intramembrane domain also contains the signal for ER targeting.
Sequence:
MQWFGGNVATAIQISRKNKALLIVYITTDSEDGQIFDGFWQHIDSSNLLCAVVGIKLKAGETSAQQFADIYPTPILPAAYLIDQNGKPLEVITPLVGKTYDQFRAKFDKATAQFVNGMPTAAANQLSTPSPSPAPVQVPASTDAPIPAPTPVTAPIQSSSTSQEMTRELAEKVARAKALLEQKKQKDAEKKREADKHVKEEMTKAREAKQERDAEALVKAAKQRKMEKLAAESDKKRILAQIKADREAAQKKFGKLVNTENASENTEKKQETTVGKAVPSDRCRLQVRLPDGSTFVEEFPSNDVLNSLVEIIRQKPSIAGTTFEIQQPYPRRIFTNDDYSKTFLENQLTPSTALVVIQKSSGSSSNYGSFSLSTQTVSFVTWVLYPLTAFWNIFCGMIGWNSTGKQQDSKSKKNDGPSTSGQSGSQPQRRGMPRSAEVRRRGNVAGLENPNEDDPEERASFNGNSTQFM
The following text describes a protein:
Function:
Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity.
Subcellular Localization:
Nucleus.
Sequence:
MQEGELAISPISPVAAMPPLGTHVQARCEAQINLLGEGGICKLPGRLRIQPALWSREDVLHWLRWAEQEYSLPCTAEHGFEMNGRALCILTKDDFRHRAPSSGDVLYELLQYIKTQRRALVCGPFFGGIFRLKTPTQHSPVPPEEVTGPSQMDTRRGHLLQPPDPGLTSNFGHLDDPGLARWTPGKEESLNLCHCAELGCRTQGVCSFPAMPQAPIDGRIADCRLLWDYVYQLLLDTRYEPYIKWEDKDAKIFRVVDPNGLARLWGNHKNRVNMTYEKMSRALRHYYKLNIIKKEPGQKLLFRFLKTPGKMVQDKHSHLEPLESQEQDRIEFKDKRPEISP
The following text describes a protein:
Function:
Transfers N-acetylgalactosamine onto globotriaosylceramide. Plays a critical role in preimplantation stage embryonic development.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MSVRNLKWSLWLLSFLTVAMVWYLNLPSYTEIENFSWMYFYEYKPIYRQKFAFTLRERVTCSKKDPFLVILVASHPTEVKARQAIRITWGAKKTWWGQEVITYFLLGHQEEPKDNMLTLSVQDESILYGDIIRQDFLDTYYNLTLKTIMAFRWVAEFCPNAKYIMKADNDVLINPGNLVKYLLTYNQSENFYTGYPFLKSYSKREFFRKTYIPYEEYPFKVFPPYCSGFGYVFSVDLALRVYEMMAHVKPIRLEDAYIGIILGILKNAVPVALEKGCF