lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KinC, the RapA phosphatase and the Spo0A sporulation protein.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on FtsZ. Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Sequence:
MIKILGRHLRESFKSLGRNTWMTFASISAVTVTLILVGVFLVIMLNLNNMATNAEKQVEIKVLIDLTADQKAQDKLQNDIKELKGIQSVTFSSKEKELDQLVDSFGDSGKSLTMKDQENPLNDAFVVKTTDPHDTPNVAKKIEKMDHVYKVTYGKEEVSRLFKVVGVSRNIGIALIIGLVFTAMFLISNTIKITIFARRKEIEIMKLVGATNWFIRWPFFLEGLLLGVFGSVIPIALVLSTYQYVIGWVVPKVQGSFVSLLPYNPFVFQVSLVLIAIGAVIGVWGSLTSIRKFLRV
The following text describes a protein:
Function:
Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQQHQTGRTLTMASLGCGFVGPVVGGWYRVLDHLIPGTTKVNALKKMLLDQGGFAPCFLGCFLPLVGVLNGMSAQDNWAKLKRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVVWNSYLSWKAHQL
The following text describes a protein:
Function:
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity). Plays a role in the catabolism of hexuronates under osmotic stress conditions, likely substituting for the regular hexuronate degrading enzyme UxaC whose expression is repressed in these conditions.
Sequence:
MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDRIIVGGIMPITKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTGTPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR
The following text describes a protein:
Function:
Catalyzes the prenyl-FMN-dependent decarboxylation of pyrrole-2-carboxylate (P2C). Can also catalyze the carboxylation of pyrrole in the presence of elevated concentrations of CO(2) or bicarbonate. Can accept a modest range of heteroaromatic compounds such as 3-methylpyrrole-2-carboxylate, indole-3-carboxylate and furan-2-carboxylate, and shows very low activity with thiophene-2-carboxylate. Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed.
Domain:
Consists of three domains: an N-terminal alpha/beta domain, a split beta-barrel with a similar fold of a family of flavin reductases and a C-terminal alpha/beta domain with a topology characteristic for the UbiD protein family.
Sequence:
MNRSALDFRHFVDHLRRQGDLVDVHTEVDANLEIGAITRRVYERRAPAPLFHNIRDSLPGARVLGAPAGLRADRARAHSRLALHFGLPEHSGPRDIVAMLRAAMRAEPIAPRRLERGPVQENVWLGEQVDLTRFPVPLLHEQDGGRYFGTYGFHVVQTPDGSWDSWSVGRLMLVDRNTLAGPTIPTQHIGIIREQWRRLGKPTPWAMALGAPPAALAAAGMPLPEGVSEAGYVGALVGEPVEVVRTQTNGLWVPANTEIVLEGEISLDETALEGPMGEYHGYSFPIGKPQPLFHVHALSFRDQPILPICVAGTPPEENHTIWGTMISAQLLDVAQNAGLPVDMVWCSYEAATCWAVLSIDVQRLAALGTDAAAFAARVAETVFGSHAGHLVPKLILVGNDIDVTEIDQVVWALATRAHPLHDHFAFPQIRDFPMVPYLDAEDKARGSGGRLVINCLYPEQFAGQMRAATASFRHAYPTALRRRVEERWSDYGFGDA
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with ube2n/ubc13 to amplify the rnf8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the rnf8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of tp53bp1 and brca1. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
Subcellular Localization:
Nucleus. Note=Localizes to double-strand breaks (DSBs) sites of DNA damage.
Domain:
The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
Sequence:
MAKVQKLPLPWSECICPICQEILLEPVTLPCKHTLCNPCFQMTVEKASLCCPFCRKRVSTWARQHSRTRTLVNKELWEVIQKQYPKQCQRRASGQESDDLSDELTSCPVPVLCKPGEIRQEYEAEVSKIEAERTAQEEAERKASEDYIQKLLAEEEAEENLHAEASQREIEEQLKRDEELARLLSGDMDLSNASCTSVSPVTSKKVVSKSSKIVKSKQRVSGDIERFLSPKPRRALAAFGINESRNSDTSGSCILLDEDEDEIPDLSPQCPSTSLIQERDVELPMPYLPNCYKLESDAASQQDSCSERNDICNGTYSCSDSIDVEVSKTMEQQRATADSQEYRMETNAMSYSTPKRKCEECYLDIEEKAGSCQSVKKKKLSLSEDSPVLSVHAGKFIELEENLYERRKQEEHDRLFALQLQRELDKELKQVNRGKGSPDEYQLRPKRGLKLQECNDSPLPHNEQTPVQDKGGNTQSGYSPDENKKPSRKKSITSSQVRQSRAVTNTERSSEGMNVLKPSNKQPTILDLFQRSAGK
The following text describes a protein:
Function:
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Dispensable for SPC enzymatic activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAEGQSDTFWKSLYIYFNEMDFESQLFVKKIYKIIILTVAIISFIIAFFLERFSVCVYSTIGSSVLCILVLAPAWPMWKKNQPNWQQANQQKQK
The following text describes a protein:
Function:
Protein-lysine methyltransferase that selectively mono-, di- and trimethylates 'Lys-165' of the translation elongation factors EEF1A1 and EEF1A2 in an aminoacyl-tRNA and GTP-dependent manner. EEF1A1 methylation by EEF1AKMT3 is dynamic as well as inducible by stress conditions, such as ER-stress, and plays a regulatory role on mRNA translation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
The following text describes a protein:
Function:
Microtubule-associated protein required for seed development and for microtubule function in the endosperm. Associates with nuclear microtubules during mitosis. Binds to microtubules of the spindle and spindle-poles and to midzone microtubules out of which the phragmoplast emerges. Not associated with cortical microtubules. Required for endosperm cellularization. May be bound and sequestered by GRF5 in an inactive soluble form during the early stages of mitosis.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.
Sequence:
MEARIGRSMEHPSTPAINAPAPVPPPSTRRPRVREVSSRFMSPISSSSSSSSSSSAGDLHQLTSNSPRHHHQHQNQRSTSAQRMRRQLKMQEGDENRPSETARSLDSPFPLQQVDGGKNPKQHIRSKPLKENGHRLDTPTTAMLPPPSRSRLNQQRLLTASAATRLLRSSGISLSSSTDGEEDNNNREIFKSNGPDLLPTIRTQAKAFNTPTASPLSRSLSSDDASMFRDVRASLSLKNGVGLSLPPVAPNSKIQADTKKQKKALGQQADVHSLKLLHNRYLQWRFANANAEVKTQSQKAQAERMFYSLGLKMSELSDSVQRKRIELQHLQRVKAVTEIVESQTPSLEQWAVLEDEFSTSLLETTEALLNASLRLPLDSKIKVETKELAEALVVASKSMEGIVQNIGNLVPKTQEMETLMSELARVSGIEKASVEDCRVALLKTHSSQMEECYLRSQLIQHQKKCHQQECTTSV
The following text describes a protein:
Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Sequence:
MSFDDLTDNTKSVRNIPGAKFIEHVTEFLQNKNEESILRLARELLLKYKFMEHAFVSRQINTQKKIPELKDALRVVQLLEKRKKIKEKKNLETFFPVEESLYARGIVQKTDKILLWLGANVMVEFPFDEATDLLNQHLERAINLSQEMDNELLWLHEQITTTEINISRIHNYIELKKGMMGKEVDKKTEQVN
The following text describes a protein:
Function:
Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
Subcellular Localization:
Peroxisome.
Sequence:
MRRQWGSAMRAAEQAGCVVSAFRAGQPEAGPWSCSGVILSRSPGLVLCHGGIFVPFLRAGSEVLTAAGAVFLPGDSCSDDLRLHVQWAPTAAGPGGGAERGRPGLCTTQCASLEPGPPAPSRGRPLQPRLPAELLLLLSCPAFWAHFARLFGDEAAEQWRFSSAARDDEVSEDEEADQLRALGWFALLGVRLGQEEVEEERGPAMAVSPLGAVPKGAPLLVCGSPFGAFCPDIFLNTLSCGVLSNVAGPLLLTDARCLPGTEGGGVFTARPAGALVALVVAPLCWKAGEWVGFTLLCAAAPLFRAARYALRRLPHSTAALAALLPPEASVPWGLPLRDSGLLWAAAAVLVECGTVWGSGVAVAPRLIVTCRHVAPREAARVLVRSTTPKSVAIGGRVVFATQETCPYDIAVVSLEEDLDDVPIPVPAEHFHEGEAVSVVGFGVFGQACGPSVTSGILSAVVQVNDTPIMLQTTCAVHSGSSGGPLFSSHSGNLLGIITSNTRDNNTGATYPHLNFSIPITVLQPALQQYSQTHDLGGLRELDRAAEPVRVVWRLQRPLAEAPRSKL
The following text describes a protein:
Function:
TasA is the major protein component of the biofilm extracellular matrix. It forms amyloid fibers that bind cells together in the biofilm. Exhibits an antibacterial activity against a variety of Gram-positive and Gram-negative bacteria. In laboratory strains, is also involved in proper spore coat assembly.
Subcellular Localization:
Secreted. Forespore intermembrane space. Note=In undomesticated strains, is secreted and primarily associated with the extracellular matrix. In laboratory strains, is secreted into the medium early in sporulation and is also incorporated into the spore. Processing, export and incorporation into spores depend on SipW.
Sequence:
MGMKKKLSLGVASAALGLALVGGGTWAAFNDIKSKDATFASGTLDLSAKENSASVNLSNLKPGDKLTKDFQFENNGSLAIKEVLMALNYGDFKANGGSNTSPEDFLSQFEVTLLTVGKEGGNGYPKNIILDDANLKDLYLMSAKNDAAAAEKIKKQIDPKFLNASGKVNVATIDGKTAPEYDGVPKTPTDFDQVQMEIQFKDDKTKDEKGLMVQNKYQGNSIKLQFSFEATQWNGLTIKKDHTDKDGYVKENEKAHSEDKN
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. May be an antioxidant enzyme particularly in the developing shoot and photosynthesizing leaf.
Sequence:
MACSAPAILSSKPSAFSCKSEMPLASISPSKPFAQRQSLTIPKSFNGLRKPFQSRASRPISTRSSSSRRSFVVNASSELPLVGNAAPDFEAEAVFDQEFIKVKLSDYIGKKYVILFFYPLDFTFVCPTEITAFSDRYADFEKLNTEILGVSIDSVVSDPPHLHPPKQELLKYXLISDVTKSISKSYGVLIPDQGIALRGLFIIDKEGIIQHSTINNLAIGRSVDETMRTLQALQYVQENPDEVCPAGWKPGEKSMKPDPKLSKEYFAAI
The following text describes a protein:
Function:
Costimulatory molecule that belongs to the immunoglobulin superfamily that plays an important role in T-lymphocyte activation. Acts as the primary auxiliary signal augmenting the MHC/TCR signal in naive T-cells together with the CD28 receptor which is constitutively expressed on the cell surface of T-cells. In turn, activates different signaling pathways such as NF-kappa-B or MAPK leading to the production of different cytokines. In addition, CD28/CD80 costimulatory signal stimulates glucose metabolism and ATP synthesis of T-cells by activating the PI3K/Akt signaling pathway. Also acts as a regulator of PDL1/PDCD1 interactions to limit excess engagement of PDL1 and its inhibitory role in immune responses. Expressed on B-cells, plays a critical role in regulating interactions between B-cells and T-cells in both early and late germinal center responses, which are crucial for the generation of effective humoral immune responses (By similarity); (Microbial infection) Acts as a receptor for adenovirus subgroup B.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: Soluble isoform. Expressed in unstimulated B-cells and monocytes, but not T-cells; MISCELLANEOUS: [Isoform 3]: Soluble isoform. Expressed in T-cells activated by ConA, non-activated monocytes and monocytes activated with IFN-c.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGVIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCFAPRCRERRRNERLRRESVRPV
The following text describes a protein:
Function:
Involved in formation and maintenance of cell shape.
Sequence:
MLELIRKYRVYIVAAVALLAALTFYSLNLRQKEQANLFERVIIDLFAPVYNLGSRVSTFMGSVWGDYIDLVDVRRENKELRESVKILNGRIMEHREAIHENGRLRQLLGLKGTVGLPSVAAQVIGEDNSPWFKTLVINRGAVDGLAEGMPVVAASGVVGQLVKVAAGSSRVLLLTDHASGIAAVVQRSRARGVVKGQGGGLCSLEFSLREEDVKVGDVVVSSGMGGIFPKGLVIGEVTMVKKGEYGIFQNINIRPAVNIARLEEVLVLIPRNND
The following text describes a protein:
Function:
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVPVILEVAGIGKYAISIGGERQEGLTEEMVTQLSRQEFDKDNNTLFLVGGAKEVPYEEVIKALNLLHLAGIKSVGLMTNPI
The following text describes a protein:
Function:
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Sequence:
MDTLTNSQDYSNVDLSLESLAEELYNIQSFNKDVILDSFDIDDYDHTQLDTTIDFNKFKIGLTILKISSKGKPQKKKLIFDLARNQIVCGKKKKVNFSEIDEIRVGHKTNIFNQFKSSKNLKEDIESIQQSFSILFSGNLRKTMDFVCSDIPERRQIVSALYHVVQESKSVNNEYNFVKREWDRVGKDSIDFSTLKKILARLNFTTSDAVLHNLMKFSDSNSDYHLDFSEFSNLLKLLRSHPEMKPVFYKYNGGNGEWVPIQGMIDFFRIEQSEVWTVEQCRDLIKKYHHERLDCISFENFEEFICGEANLAQYPHTSTVYQDTSKPLSYYFINSSHNTYLSGHQLKGLSTSEMYTNTLRQGCKCVELDVWDGNDGDPIIFHGNTLTSQIKFSHVCETIKARGFETSPYPVILSLEVHCSVPQQIMMANHMKEIFGEMLPTPLPEGTKELPTLDSLKYKILLKGHTSHTHVSAVGNSSASSSQSNIQTDDNDDDGAVDLTEYDEVDDRSASSSSSSFSLSFGSSGKKKKITKIKIAPEFEELIYLVSHGFKSGNTTKEIPSYKIHSLVEEKVKQLVQSEPREVVEASQNHLLRVYPRGTRFDSSNFDPMPGWSIGCQLAALNQQTSSEPMWINDGMFSDNGGCGYVLKPPCLLPGECETYDPTSPERIKSSKYSRLIVNVISARQLPKYTKSTKGEVIDPYVTLSIVGTHFDQKVEKTKVIDNNGFNPHWGEEFEFPLYNSQLSMLLIRVDDKDKVGHNRIGHHCIRVENIRPGYRILKLKNNFNRTIPLANLLCKFTFVE
The following text describes a protein:
Function:
Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
Subcellular Localization:
Cytoplasm.
Sequence:
MPDIVNRKVEHVEIAAFENVDGLSSSTFLNDVILVHQGFPGISFSEINTKTKFFRKEISVPVMVTGMTGGRNELGRINKIIAEVAEKFGIPMGVGSQRVAIEKAEARESFAIVRKVAPTIPIIANLGMPQLVKGYGLKEFQDAIQMIEADAIAVHLNPAQEVFQPEGEPEYQIYALEKLRDISKELSVPIIVKESGNGISMETAKLLYSYGIKNFDTSGQGGTNWIAIEMIRDIRRGNWKAESAKNFLDWGVPTAASIMEVRYSVPDSFLVGSGGIRSGLDAAKAIALGADIAGMALPVLKSAIEGKESLEQFFRKIIFELKAAMMLTGSKDVDALKKTSIVILGKLKEWAEYRGINLSIYEKVRKRE
The following text describes a protein:
Function:
Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation.
Miscellaneous:
MISCELLANEOUS: Overexpression mutant display larger leaves and cotyledons, as well as a delayed bolting of the inflorescence stem when compared to wild-type plants.
Subcellular Localization:
Nucleus.
Domain:
The QLQ domain and WRC domain may be involved in protein-protein interaction and DNA-binding, respectively.
Sequence:
MDIGVHVLGSVTSNENESLGLKELIGTKQDRSGFIGEDCLQRSLKLARTTTRAEEEENLSSSVAAAYCKTMSFHQGIPLMRSASPLSSDSRRQEQMLSFSDKPDALDFSKYVGLDNSSNNKNSLSPFLHQIPPPSYFRSSGGYGSGGMMMNMSMQGNFTGVKGPFTLTQWAELEQQALIYKYITANVPVPSSLLISIKKSFYPYGSLPPSSFGWGTFHLGFAGGNMDPEPGRCRRTDGKKWRCSRDAVPDQKYCERHINRGRHRSRKPVEVQSGQNQTAAAASKAVTTPQQPVVAGNTNRSNARASSNRSLAIGSQYINPSTESLPNNRGVSIYPSTVNLQPKESPVIHQKHRNNNNPFEFGHISSDSLLNPNTAKTYGSSFLDFSSNQEKHSGNHNHNSWPEELTSDWTQLSMSIPIASSSPSSTHNNNNAQEKTTLSPLRLSRELDLSIQTDETTIEPTVKKVNTWIPISWGNSLGGPLGEVLNSTTNSPTFGSSPTGVLQKSTFCSLSNNSSVSSPIAENNRHNGDYFHYTT
The following text describes a protein:
Function:
Catalyzes the desaturation of short-chain acyl-CoAs to 2-trans-enoyl-CoAs. Active on butyryl-CoA (C4), hexanoyl-CoA (C6), and octanoyl-CoA (C8). Has no activity as acyl-CoA dehydrogenase or on crotonyl-CoA (an unsaturated C4:1 carbocyclic ester) or glutaryl-CoA (a dicarboxylic ester). Peroxisomal fatty acid beta-oxidation is essential for embryo development. Acts as a suppressor of transcriptional silencing. Required for nuclear histone acetylation and DNA demethylation at some endogenous genomic loci.
Subcellular Localization:
Glyoxysome. Peroxisome.
Sequence:
MAVLSSADRASNEKKVKSSYFDLPPMEMSVAFPQATPASTFPPCTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNSFQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEGTYDINTLVTGREVTGIASFKPATRSRL
The following text describes a protein:
Function:
May be involved in acrosome formation of spermatids.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSGGYDLNLFASPPDCKFLCSVCHGVLKRPTRLPCSHIFCKKCIFRWLARQNTCPCCRKEVTRRKMVEVNKLRKTIGRLQVKCKNAAAGCLDTHPLAHRKEHQDSCPFELMACPNEGCTVQVLRGVLDEHRQHCQQNGQQRCPLGCGSTLAALEGEHHNCYRELRDAWVQRHERNRTLLLGLLGRVRRVHLTTSIIHQQLAQLSNFLEDDDNLLLNAQVQETEVTPEAEMRGTQGQSVL
The following text describes a protein:
Function:
Peripheral baseplate protein that is part of the tail fiber network. Connects the long tail fibers to the baseplate and, after virus attachment to a host cell, probably changes its conformation to trigger the signal for tail contraction. Involved in the tail assembly.
Subcellular Localization:
Virion. Note=Present in 18 copies in the baseplate.
Domain:
The C-terminus is bound to the baseplate, and the N-terminus coiled-coil domain is associated with the long tail fibers.
Sequence:
MFIQEPKKLIDTGEIGNASTGDILFDGGNKINSDFNAIYNAFGDQRKMAVANGTGADGQIIHATGYYQKHSITEYATPVKVGTRHDIDTSTVGVKVIIERGELGDCVEFINSNGSISVTNPLTIQAIDSIKGVSGNLVVTSPYSKVTLRCISSDNSTSVWNYSIESMFGQKESPAEGTWNISTSGSVDIPLFHRTEYNMAKLLVTCQSVDGRKIKTAEINILVDTVNSEVISSEYAVMRVGNETEEDEIANIAFSIKENYVTATISSSTVGMRAAVKVIATQKIGVAQ
The following text describes a protein:
Function:
Catalyzes the exchange of ADP and ATP across the membrane.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPDRTKSRPTHVGISLKFRFLSEDLYRGLLRNSSTSREKNHHLFSEGLCFGGFDTVKEVLSEEDKELALWVRWVLAQGVTTFAGFASHPLDTVRRRIMMQSGIENPMYRSEGLASFYRGALSNMFRSIGSAAILVLYDEVKKFLNWRGDLRGKLL
The following text describes a protein:
Function:
dsDNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance (By similarity). FANCM-MHF promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork (By similarity). Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (By similarity).
Sequence:
MVKQQSKEEIALQLKSAVYLSVAKIVEAKLEDLNNDNAATTTTESNNKNNNNNMLIATPTFIAQLVELVYNQLINLGEDLELFCQHANRDIVEPSDLFMVTRKNPTLQQHLKDLLRQ
The following text describes a protein:
Function:
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
Sequence:
MNSSKSSKHNVQNTTYEAASSKLSAVKLGYYDDPFLKHFVKRIETRSPLINRGYYARVAALRLYIELFFKSIDNKQSIQIVNIGSGLDTTFFWINQKYQDVKYYEIDFYDLLKEKTDIIKKYTEMKNFLKYEKDNEEKDEDLINCLNYKMVPLDLNDSSSFEKILLSYNFDFNKPTIFICECVLIYLETESSDNLIKKLSELMKNTSCIIVYEQVNPNTAFGKVMIDNFSHRGINLKSIYKYYNLQTQLERYKSLGWVNVYINDMNEIYDYHINMEEKKKIELIEMFDEFEEWRLLQNHYFILVAFNCYNNINLEELKQFLTCQKEK
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MQTAWILIAQSPDFVTSAVIHRMLNSPRRGQAMGKNVTMWITKPSNFVFGSLLIVVVVMVYWGGFVVNRATANSTLASAFGWSPATQLKEFPAYSTSSLANLSTGKLPVESPLRIPIKSLIDALRKAVTTVEKLTGVSADRDIDLNLWRLQNPCKSRTELSSFYSRISYSPNRKTPGRSETKQWGTVLFEYARFHRVCTRAAGNLTEYFFERNTSTGCKFMIADAKNGMGNKLFIMAPALVYAVLTQRVFLISESTGVPDLMCEPFPGSSWRLSEDIVSYSVPIWNETREFMGDVDRAKREHESTIPMYASRIDDNWQPNSRFFCDVEQSYFRQVPWLTIHGCLYFLPKLFAIPSIRKTLEALFPDPTLALTQILRANFLPRDQTWARVSTVKKYFDSAHTQTGIQARYFNNSATKHKILNANVESCLLENNLLEQAIPAQEKDHETTIFIASLTPDLQEHLRGVYNRSTTSLPTSLNFVQLSNEIEQRFGAEAYDQALVEVLRLSFSHTLLLSPQSTFGGLAQAYGALTPWIVESRDEVLTPCERAQSVDNCYQIPELEYKCRYDGADSKLGRAIAGAVNYIKPCLAIDTHHRSGLQLVAIP
The following text describes a protein:
Function:
Adenine glycosylase active on G-A mispairs; Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.
Subcellular Localization:
Mitochondrion. Nucleus.
Sequence:
MTRRAARRAAGGTRHFRLRSPRGSRGRAGTGRGLALGRSDFRSHLPGRCGGGGAARAGAYRRGPRPTSPGCTSPGVRRRGARETERESLAETQPEWSYLSVQPAKSKLLSLWRAIMKKPQAAVRSRLRKQASRQEGSEKRVLSSSQVKPSTAAGLAKRQEAAWQASVSSYHLFRDTAEVMAFRENLLNWYDREKRDLPWRRLAEGEVDLDRRAYAVWVSEVMLQQTQVATVIDYYTRWMQKWPTLQDLAGASLEEVNQLWAGLGYYSRGRRLQQGARKVVEELGGHVPHTAETLQRLLPGVGRYTAGAIASIAFGQATGVVDGNVIRVLCRVRAIGADSSSTLVSQHLWGLAQQLVDPARPGDFNQAAMELGALVCTPQHPHCSQCPVRSLCRAYQKVERGKLLASQSLPGSPDVEECASSTELCQLCAHPTEPWDQTLGVTNFPRKASRKPPREECSAICVLEQPRALGGPQILLVQRPSSGLLAGLWEFPSVTAEASGRCQREALLQELQSWAGPLPASHLQHLGQVVHTFSHIKLTYQVYGLALEGQTPVTIVPPGARWLTREEFHTAAISTAMKKVFRVYEGQQPGICKGSKRSQVSTPSSRKKPSPGQQLLDSFFRPLIPTDSSNLNSMAQ
The following text describes a protein:
Function:
Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer. Receives 2Fe/2S clusters from scaffold protein ISU1 and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion.
Miscellaneous:
MISCELLANEOUS: Present with 6260 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MFLPKFNPIRSFSPILRAKTLLRYQNRMYLSTEIRKAIEDAIESAPVVLFMKGTPEFPKCGFSRATIGLLGNQGVDPAKFAAYNVLEDPELREGIKEFSEWPTIPQLYVNKEFIGGCDVITSMARSGELADLLEEAQALVPEEEEETKDR
The following text describes a protein:
Function:
Involved in the secondary bile acid metabolism. Catalyzes two subsequent reductions of the double bonds within the bile acid A/B rings of 3-oxochol-4,6-dien-24-oyl-CoA and 12alpha-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA to yield 3-oxocholan-24-oyl-CoA and 12alpha-hydroxy-3-oxocholan-24-oyl-CoA, respectively.
Sequence:
MNRIGIIGGGASGIVAAIAAARSDGDAQVFILEQKENIGKKILATGNGRCNLTNEAMDASCYHGEDPEFARNVLKQFGYGETLEFFASLGLFTKSRGGYIYPRSDQAASVLELLEMELRRQKVKIYTGVRVEALKLSAKGFVIRADGQRFPADRVILACGGKASKSLGSDGSGYALARSMGHTLSPVVPALVQLKVKKHPFAKAAGVRTDAKVAALLGRQVLAEDTGEMQITAYGISGIPVFQISRHIAKGLYEGKEMKVRVDFLPEMEASQVRKAFNTHLDKCPYATCQEFLTGIFPKKLIPRLLELSHIRQNFPASELKPAQWEDLIRACKQTLLTIEDTNGFDNAQVCAGGVRTGEVYPDTLESRYADGLYLTGELLDVEGICGGYNLQWAWATGYLAGRAAAERP
The following text describes a protein:
Function:
Involved in viguiepinol biosynthesis. Catalyzes the conversion of copalyl diphosphate (ent-CDP) into pimara-9(11),15-diene (PMD).
Sequence:
MRARHRVALKVLADLRSWAAEYPQVLEATPIEALAISTAAISPWRGANELRLSAPDVRCGPTPLDDHVEQNVRSLDELDDLFGRCEAIVRGGDRDDGHPLLASLSGWQSALERAPHYPKLAGLWGDRFAEALRGERYDWTAGLARDRGEGPSDPQEYLTYAASSNAWITHFPRWATSDRDDLLDGLPVLDNALEAIEVAVRLSNDLATFERERAEPGQNNILMYDTSPDWVHDELDRHSRKAQEQLDPLATAGFPPAVELLRLLDWSVTFYSGADFRGWGSDRDLTGPSGLPSDM