lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for plastid separation and partitioning during cell division. Not involved in plastid constriction or in the organization of cytoplasmic actin cables. Contributes to polar growth of root hairs.
Subcellular Localization:
Cytoplasm. Note=Localized to distinct foci in the cytoplasm, which frequently colocalize with the cell periphery and with chloroplasts.
Sequence:
MGKSGGRKKKSGGSNSNSSQVNSSETSGLSKPSTIVNGGVDFDASIFLKRAHELKEEGNKKFQARDYVGALEQYENGIKLIPKSHPDRAVFHSNRAACLMQMKPIDYESVISECSMALKSQPGFTRALLRRARAFEAVGKFDLAVQDVNVLLGSDPNHKDAGEISKRLKTALGPHQDLQSRPSPAALGASAALGGPIAGLGPCLPSRNVHKKGVTSPVGSVSLPNASNGKVERPQVVNPVTENGGSVSKGQASRVVLKPVSHSPKGSKVEELGSSSVAVVGKVQEKRIRWRPLKFVYDHDIRLGQMPVNCRFKELREIVSSRFPSSKAVLIKYKDNDGDLVTITSTAELKLAESAADCILTKEPDTDKSDSVGMLRLHVVDVSPEQEPMLLEEEEEEVEEKPVIEEVISSPTESLSETEINTEKTDKEVEKEKASSSEDPETKELEMDDWLFDFAHLFRTHVGIDPDAHIDLHELGMELCSEALEETVTSEKAQPLFDKASAKFQEVAALAFFNWGNVHMCAARKRIPLDESAGKEVVAAQLQTAYEWVKERYTLAKEKYEQALSIKPDFYEGLLALGQQQFEMAKLHWSYLLAQKIDISGWDPSETLNLFDSAEAKMKDATEMWEKLEEQRMDDLKNPNSNKKEEVSKRRKKQGGDGNEEVSETITAEEAAEQATAMRSQIHLFWGNMLFERSQVECKIGKDGWNKNLDSAVERFKLAGASEADIATVVKNHCSNEAAATEGDEKKVPAP
The following text describes a protein:
Function:
Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, including leaves shape, pedicule elongation, inflorescence organization and fruit maturation, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MKTTGSSVGGTKRKMWSRGVGGVVREQKAKLYIIRRCVVMLLCWHD
The following text describes a protein:
Function:
Required for the biogenesis of cytochrome c oxidase. Probably for its assembly into an active holoenzyme.
Miscellaneous:
MISCELLANEOUS: Present with 468 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MGLFNNFKFKYTRAQLEIFRFSFCLLAPVAVMYYIGTDTDKKLNVPGFWPDPATLNQIPKEPYEIKAELARMKKERLEKRLRLEKKIQEEFGLDLEEEKEKIKRDLALKKG
The following text describes a protein:
Function:
Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.
Subcellular Localization:
Cell envelope. Cell membrane.
Sequence:
MFQWLYDVLWLLAPIWIRRYLDKRSGSAPAYRAHRDERFGKPYPNPVTGAVWIHAVSVGETRAAQSLIRELRRRFPDAPLLMTQMTPTGRETAQVLFPDAQCRYLPYDKKTWVRQFLREHRPMFGILMETEIWPNLMRECRRAGVPLFLANARLSEKSLNGYLKVRRLIRPAAASLTGCLAQTEADAARLAKLGAASVQVCGNTKYDIIPSEQMKTLAGQFEKRIGGRPVAVCGSTRVYRGEDEAEKLLAAWQQYRGDALLVVVPRHPEHFQTVFETAKRFGFKVQRRSDGLPVEPDTQVWIGDSMGELYAYYLCADVAFVGGSLVDSGCQNIIEPLSCGVPTIFGFSTYNFSEACRHALASGAAVQVESADAWREAVEKTLSSEGGGMQMQARVDGFIAQHRGAGARIAEAVREAVCGYRGR
The following text describes a protein:
Function:
Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MVSTTKIKSVDFYRKIPRDLTEASLSGAGLSIIAALAMVFLFGMELSTYLAVTTNTSVIVDNSSDGDFLRIDFNVSFPSLSCEFASVDVSNVLGTKRLNLTKTIKKVPIDPYLRATGAEVHSTSGLHLINHGDEDHGNNTYAAIPLTGATFDKFSHHFQILVVNFYAPWCYWSNRLKPSWEKAAEITRQRYNPETDGRVLLGSVDCTEETTLCKRNHIQGYPSIRIFRKGSDLKEDHGHHEHESYHGDRDTESILKMVEELLKPIKKEDHKLALDGKTDNVVSGIKKAPVSGGCRIVGYVRAKKVPGEIIISAHSGAHSFDASQMNMSHYVSHLTFGKMISERLLTDMKRLMPYLGLSHDRLNSKWFVNEGQFAANVTIEHYLQVVKTEVVSRRFGQEHSVIEEYEYTAHSSVAHGYYYPVAKFRFDLSPMQVLISENPKSFSHFITNVCAIIGGVFTVAGILDSIFQNTFRLVKKIELGKNI
The following text describes a protein:
Function:
Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Specifically binds acetylated lysines on histone 3 and 4. In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and may play a role in neural development (By similarity). Plays an essential role in heart and skeletal muscle development.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc fingers mediate the binding to acetylated histones.
Sequence:
MATVIQNPLKALGDQFYREAIEHCRSYNARLCAERSVRMPFLDSQTGVAQNNCYIWMEKRHRGPGMAAGQMYTYPARCWRKKRRLHTPLDPQLRLCELRLEAELMAKREAPQTEATALEALLRGDGILDKRNNNAKEEETLLEIQRVLEADENGDGFHDDEDFEVDTPKRKHRNKGRGRGSGRRRTEAVANDDQDKPYVCDNRYKQKHNSKTADSVCGKRYKNRPGLSYHYAHTHLAEEEGEEERETEIPQSPPVHHENHKPQKAPDGSIIPNDYCDFCLGDSGSNRKTGQAEELVSCSDCGRSGHPSCLQFTDNMMQAVRTYQWQCIECKSCSLCGTSENDDQLLFCDDCDRGYHMYCLKPPMTQPPEGSWSCHLCQNLLKDKASGVEDP
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MSLLSRRLFGQARSSLSRDAVSTSAWGIRHESSSAIAQRTVASGSCSTDSAPPTHYRITLRRSGIGMPEKINRTLQGLGLKKRLQSVYRPIGPAMAGAILAVKELVHVENVRRLSDADQMLLSDQDAVWVNEAGEIVDPGKAAKKAPRGYKIVGNVVSEVRDQQIKNASS
The following text describes a protein:
Function:
Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind specifically to the receptor in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. Also required for protein transport from the Golgi apparatus to the endosomes. May also mediate transport from the endoplasmic reticulum to the Golgi.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein; Extracellular side. Lysosome membrane; Single-pass type I membrane protein.
Sequence:
MSTVLCCVLVLLISVALCMDFEERPSSSWRSEQTMFLKSHKSRNLLSLRDLQQPDHGKMKRSEESAQNQCESLHGYQSTLQNDTHTHNFNDLSGSVSLAWVGDGTGVLLVLTTFQVPLFIMRFGQSKLYRSEDYGKTFQDITDLINNTFIQTEFGIAIGPDNSGKVILTGDLAEGKVTKIFRSVDFGKSFVTSELPFHPLMQITYNPKDSNILMVYSINYDLWLSKDFGANWKKIHESVCLVKWGIDDTIFLTTNPNGSCSDRGTLELRKSLDYGKTFKTIGNRIYSFGLGGRFVFASIMTDSGSTRMIHVSVDQGETWDMAQLPTVGHEQFYSILAANNDMVFMHVDEPGDSGIGTIYISDDRGIVFSKSLERHLYTTTGGDTDFTNITSLRGVYITSVLAEDGSVQTVITFNQGGEWRPLMKPWNGVCDSTAKHPSECSLHIHASYSISMKLNVPMQPLSETNAVGLVLAHGSVGGAVSVLSPDVYVSDDGGYTWFQALKGPHHYAILDSGGLLVAVEHNPTHPISQIKFSTDEGQCWHAHNFTDDPIYFTGLASEPGARSMNVSLWGYRDTILNQYWVSVTVDFRQLLSRDCQENDYIQWLAHSSDINSPTDGCVLGYKERFLRLRRDSVCWNGRDYKVTKEPTTCPCTLTDFHDFGFYHEENSSVCVEQPDLIGHSLEFCLHGRKEQLQTSGYRKIPGDHCEEGITPERKEIDLSKKCVSNLLRTEQLTKEHSFNSAPIIAVVIIVLLISAVAGVIFIKKYVCGGRFLVHRYSVLQQHAEANGIDGLDDLDTLEGGKTHYHDDSDEDLLE
The following text describes a protein:
Function:
May be a guanine exchange factor (GEF) for Rab21, Rab32 and Rab38 and regulate endosome dynamics (By similarity). May regulate the participation of VAMP7 in membrane fusion events; in vitro inhibits VAMP7-mediated SNARE complex formation by trapping VAMP7 in a closed, fusogenically inactive conformation (By similarity). Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with Rab32, Rab38 and VAMP7. Involved in the regulation of neurite growth; the function seems to require its GEF activity, probably towards Rab21, and VAMP7 but not Rab32/38. Proposed to be involved in Golgi sorting of VAMP7 and transport of VAMP7 vesicles to the cell surface; the function seems to implicate kinesin heavy chain isoform 5 proteins, GOLGA4, RAB21 and MACF1. Required for the colocalization of VAMP7 and Rab21, probably on TGN sites (By similarity). Involved in GLUT1 endosome-to-plasma membrane trafficking; the function is dependent of association with VPS29 (By similarity). Regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
Subcellular Localization:
Early endosome. Late endosome. Cytoplasmic vesicle membrane. Lysosome. Cell membrane. Melanosome. Cytoplasmic vesicle. Note=Colocalizes with VAMP7 in transport vesicles in the shaft of hippocampal neurons.
Sequence:
MALYDEDLLKNPFYLALQKWRPDLCSKVAQIHGIVLVPCRGSLPGSVQASCQFESYVLVPTEGHFQTLDGKAVVIEGNRIKLGAGFACLLSVPILFEETFYNEKEESFSILCIAHPLERRETSEEPSAPADPFSLKTIEDVREFLGRHSEKFDKNIASFHRTFRECERKSLRHHIDSVNALYTKCLQQLLRDSHLKVLAKQEAQMNLMKQAVEMYVHHDIYDLIFKYVGTMEASEDAAFNKITRSLQDLQQKDIGVKPEFSFNIPRAKRELGQLNKCTSPQQKLLCLRKVVQLMTQSPSQRVNLETMCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSSAKDELGYCLTSVEAAIEYIRQGSLSTKTPDAEGFGDRLFLKQRMNLLSQMTSTPIDCLFKHIASGNQKEVERLLSQDDQDKDAMQKMCHPLCSCEDCEKLISGRLNDPSVVTPFSRDDRGQTPLHVAALCGQASLIDFLVSKGAVVNATDYHGSTPLHLACQKGFQSVTLLLLHYKASTEVQDNNGNTPLHLACTYGQEDCVKALVYYDVQACRLDIGNEKGDTALHIAARWGYEGIIETLLQNGAPTAVQNRLKETPLKCALNSKILSIMEAHHLSSDRRPRPSEVPAQSPTRSVDSISQGSSTSSFSSISVSFRQEEVKKDYREVEKLLRAVADGDLEMVRYLLEWTEDDLDDVEDAISTVDLEFCHPLCQCPKCAPAQKLARISANGLSVNVTNQDGFSPLHMAALHGRTDLVPLLLKHGAYSGARNTSQAVPLHLACQQGHFQVAKCLLDSNAKPNKKDLSGNTPLICACSAGHHEVAALLLQHGASINACNNKGNTALHEAVMGRHTLVVELLLFYGASVDILNKRQYTAADCAEQDSKIMELLQVVPGCVASLDSVEEADHEGYVTVEIRRKWNPKMYNLPEEPLRRQFCLINPGGRFQERTSRETMGRDRSVPDLAGRSLQEPEKQRVTGKQSDLSDLSRYQTSEEGNKGLPERPVSRQAAPGHRPMVRRHTVNDAAILQVPEVTVHLTTHEASVPQS
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MALLKTMPIIRSLTRGKSIRLLQKQSTKRTNPCVYLEAKAVEQTPATEFNSILQEIISTEYNYSVDLKKTLNEIIMPIEGQSMEREAIGICTCFKTLNQLHTKLYQQMISSGSPVYSLSQSLPAFRDVYHMYTINLSGISAIEKIISDPSSCNSQLLIPLQHLLRYPIHLARVCKMLRKYPFLNGDFRMAVKTLDDFRELCSYIDQEKAREESYQVLSALCGNQGVAVDIPRHIKFKGSVIPATSFIYDFNACVFCDDGLVVWTRYVKKIEMKAVSIEQCLRVDELSNSILVCTLNMKGKLLNRHLAPQTMAASVFLKWYHERAGISNGKENKLNRLKVVNAKT
The following text describes a protein:
Function:
Acts specifically as a negative regulator of skeletal muscle growth.
Subcellular Localization:
Secreted.
Sequence:
MQKLAVYVYIYLFMLISVDPVALEDGSQPAENGEKDGLCNACAWRQNTKSSRIEAIKIQILSKLRLEQAPNISRDVIKQLLPKAPPLQELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLVQMEGKPKCCFFKFSSKIQYNKVVKAQLWIYLRQVQKPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKAFDENGRDLAVTFPGPGEDGLNPFLEVRVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS
The following text describes a protein:
Function:
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MLSIIVFGASGDLATKMTFPALFALYVRKIIPEDFQIIGYARSKLSQEAANKIVTAHIPIDDTVGASQKALNTFVEHYKYVPGTYDKPESFEMLNSIIAEKETAPASECTRIFYLVLPPHLFAPVSELIKSKAHPNGMVTRLIVEKPIGFDYKSADAILSDLSKHWSAKDTFKVDHFLGEDMIDGFTAIRFANSMFEPIWNREHIESVRVDFREDFGCEGRGGYFEGAGILRDVVQNHLLQLLTLLCIEEPKSQDAEDIIKCKVDFLKSLHPVSKEDIVYGQYTKSANGKVPGYRELDGVADDSEVSTFCALQLRSEAPRWKGIPIIISAGKGLDRDYFEARITFKRREGGMFPTVDSSNVLVLRVYPKEFIALKGHIKQPGFSRQIVPVTLDVKYPEAFPDTWIHKAYEVVIADAINGKHTHFISDDEVRTSWKIFDDVLDTTGDLSPLPYAFGSHHGPDATLEFFKKRNLEWD
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil.
Sequence:
MYDNPPEYVKIPPFRFVKPYQHVYKTNVKSRWLGMTLLDAMEKEFRAYNKEYYENAINEGKITVNSVRVSPEYKLEHGMQIEHATTRVEPPILDLPVDIVFEDDSFVVVSKPPSMIVHTGGGYHYNCLSAILHFEHGLKDLYVLHRLDRLTSGLLIFSKNRLLAQKFHDANSKLNVQKTYLARVQGNFSEDIKENNKPQYCVSMKDAIFACCTEEDAQKLDAKSATTKFEKLWYDPISDSSLLECKPITGRTHQIRVHLADLGHPILNDIGYGGKFIGNEIVNRNFKGLKQESIRQKDVLEGEVVEIVGKKVKLNTQEDEQQKEKNKEDQNQEEPSLLQNEQQEVAGQEKINIDKNEKVEQQIQQGQEQQIEKQQDQQQIEKQQEQLQQQQQQQQQQDKQQNQQQQVQNNIKTKLHQQQYGNTSLLNDCLSGKEEWDYHKHPLEIYLHSWKYLFNGQEFKSKEPYWYYI
The following text describes a protein:
Function:
Plays a role in the regulation of phosphate uptake.
Subcellular Localization:
Cytoplasm.
Sequence:
MVRERYIRQISALREDLLRMFSMVEQQLLRAIRCLETWDSTAAAQIINDDRQIDDAWRALEESVIHVLATQQPVVASDLRLTSVVSAIASELERIGDYANSIAKRVRRASRRAVFIPPPPQIHEMAQLALQMLNTSLEAFLRQDADLARSLTAHDERVDELEDTLRELIIAEARQDPDRFEAALDLLDMVHALERTADRATNIGERVIYLATNSQTTLN
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MAGRLAAVLEESTDDLDHSTRAAYSPPCNFYRDLIRGVAVTGGLISNSGFSSGSAHAGAAGARALCDLELRAIARRMVVDGYTQCMVQAFHDAPDDALERWFLELDVDWVLRIHEEQLQGLPLQGLVESWIRAFAVILLSMRELHLANVDEPTPASARFAKASIAKMLGFVDAIVPAAPSPSPGPGEKLWAVLNMYVCVSDAPSFKWSRRPIPQETQSIIDDINGSLSTEENRLNAAIFSTTEEVRALMEEDSWAIEIPRGGGLRYLFLLNNSCFVTQQLEPSELLAWVRINHWELPSASKRYIDCYFEVSWAHVLSCISEPNPGPLLRRWNNGSSLAKFESAFHQTYRLQRFWKVPSPELRRMLRRTITDRVISGYREYLEEHPELEKRIIFGKSTPDDLEELLGGLFEG
The following text describes a protein:
Function:
Pore-forming (alpha) subunit of a voltage-gated inwardly rectifying potassium channel. Charactherized by a fast rate of activation during depolarization followed by a rapid inactivation at much more depolarized value causing inward rectification due to a C-type inactivation mechanism. Exhibits a rapid recovery from inactivation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDSNFVLGNAQVPALFPIVYCSDGFCELTGYPRAQIMQKGCACAFLYGSDTKEDAIREIDDALENKTELKLELIFYKKNGSPFWCLLDIVPIKNEKHEVVLFLASHKDITKSKMAEIETDDADETAELDANGNVDFEGCAPSNNYQRRRSRAVLYQLSGHYRHEKKMSKLKINNNLLHSTALPEYKTAAIKKSRFILSHYGAFKTCWDWLILVATVYVAVVVPYSACFGEMQNHSLNSQQHYTLVLGLNDTSSGELGNETAGPWLGTSSSSPVPESQVDGNRTIISDVIVEAMFIIDIGLNFRTTYVNKKGEVVAKPKSVALNYLRGWFIVDLLAALPFDLLNAAGLYSRDNQMYLHLLKLTRLLRLARLLQKMDRYSQYSVVVLTLLMLMFTLVSHWLACIWFVIAVQEMESFPQNNISWLSQLSMKLEYDVLRPLDMAATYITALYFTTSSLTSVGFGNVAANTNAEKVFSILTMLIGALMHAVVFGNVTAIIQRMYARRSLYQTKLRDLKDFFRLHQLPKQLRQRMMDFFQTTWSLNNGIDPNDVLREFPDELLGDVSMHLHKEILSLPIFEPAPQGCLKLLSRHVRSNFCAPGEYLVHKGDALSYIHLVCNGSMEVLQESMVVAILGKGDLVGSDISLTSGAETVMRSSSDVKALTYCDLKCLFIPGLLEVLKLYPEFAESFCHDIVHDLTYNLREGYENEAEETNGVCSLTLPSISEDDEETDSNETAPGSPVSNTQDAAGGKPAKDEPWEAGGAAKASAAATQPLLTPAAATVRTTETVFPPRRTSVLGSPFRTPGSIAMDKLRPVATLPHLGRSVELFEIRDEMEQLRGSVDRLDVQLKSVSQDVSGLAQELRASARLLQQLCNGGQQPASPPPPPIPLLPQPHPFGPPRRVSHQGSQTDCSLLEEMLAKMADSGSPPPNSGYSSGSSNEERVKFVIGHPSPRRCIASSSDDSALLSVSRDHLVPSATLSPRSWQVSAEFTEVPASPGRSDHVVDVEDNLRRRLSTEL
The following text describes a protein:
Function:
Inhibits phosphatase activities of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) complexes.
Sequence:
MSTEMMTTEPVPPLELSDDILGKLDPQCSPSDDLSDQFIKDCDLKKKPRKGKNVQATLNVESDQKKPRRKDTPAVHIPPFIPGVISEHLIKRYDVQERIPKAKSGPALHNSDMEQKRPRRKDTPALHMPPFVAGLTLLRDESAGVILEDEEMDGDKLAI
The following text describes a protein:
Function:
Negative regulator of sarA transcription at late exponential and stationary growth phases. It contributes to the modulation of target genes downstream of the sarA regulatory cascade. Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKINDINDLVNATFQVKKFFRDTKKKFNLNYEEIYILNHILRSESNEISSKEIAKCSEFKPYYLTKALQKLKDLKLLSKKRSLQDERTVIVYVTDTQKANIQKLISELEEYIKN
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Sequence:
MGIDDFNELKLKMDDFQSKIHQFLIKNNQDLATKSETYWNSESEKIKKIEALKDKLRQLEEHQISLEEEFESSQREVSEVNAQSKAFLTKRDKLIGEREFLHKELDKLDILLKEQTKDLEREKQSRLLQSSKDTNEVALFETLLGLHISANAQDAITFHFTSRTVDVSPQLSITLDVSQDTYKITDSNPKLPQIIKNDLLNNLAATDDLRSFLKAARSHLSALTEAT
The following text describes a protein:
Function:
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells; Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
Sequence:
MYSMRGHEGIQMLLTAEQEAQQIVTAARNLKTTRLRQAEEEAEKEAGLYRSNLESEYQKRVGEVWLDISSATSISKETEAKIRNMKKSTSKFQSDVVVMLIKDVTAVNYLFLYFKNIFE
The following text describes a protein:
Function:
Forms a transiant heterodimeric complex with DCK1, that acts as a guanine nucleotide exchange factor (GEF) for the small GTPase RHO5. DCK1, LMO1 and RHO5 relocate to mitochondria upon oxidative stress and trigger cell death. The DCK1/LMO1/RHO5 signaling module mediates mitochondrial turnover under nitrogen starvation conditions via mitophagy. The DCK1/LMO1/RHO5 signaling module also plays a role in cell wall integrity signaling.
Miscellaneous:
MISCELLANEOUS: Present with 486 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Mitochondrion. Note=Quickly relocates to mitochondria under oxidative stress.
Sequence:
MKHNRQMPDESLENIKVLLNPKLGKPVKSLTSAQSKACYHTLISNKNLNKTSDEYEKLLANYILLCDEKYLCKTVIPDSRFWAILCDNCQKLRSETLVANLIRIFNVALKCQDSNKNEVIVSICHISRENSQLIGILLQLLSQRPIHIPLFTDTILCITLFLKCSLTLCETSLSHAVEFVPRILILLFQYNFPASMSELLYIEDLQPLILEEFVPLKQRLINFLSSVSIDDYSCSLKADLLTAIKDNSVFQKGLEMEMGDLPSINLLNAYDTFTFLNSPNGSFKRLYTEQLLFGENDFPLYEAIFKLSDQFRRLFNLSGKKENQYSDSERDLKLQIATAVLNRQTCFYKTLELFLRFWIESLAKSQSDLVSLLNLAIITLKYVCLSSSDLEAAIQTKSLLKTQVVALDSMRYKFARTLQLDSIKKEQYRTWSSSIASFDTMLSGQVRDYVRHQRLLQLQKGTWVYAENPLNPEAGTPKVYFLIVSDNHANLLAREFETQTNDLPYLFDNKILTSPGSEALANGRTKVVVLKHITSFKSIELTTPSRRTSSNVYIKLDEANVYTGVELKDRNDRTVLKFYLDTEEGRYIWLDGLKLISPFQHEDISEDTKEQIDTLFDLRKNVQMINLNVRQDIIVPPPEPSDEDEDEEFYNLETLKKVTQNFYFD
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP170 probably plays an important role in NPC assembly and organization. In addition it is required for chromosome transmission fidelity.
Miscellaneous:
MISCELLANEOUS: Present with 1560 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Sequence:
MFQSFFHNNGPAAAGETFSDSRSYPLTNHQEVPRNGLNELASSATKAQQQPTHILNSYPITGSNPLMRASAMGATSGSINPNMSNMNEHIRVSGMGTSKPLDLAGKYIDHLQHKDSNTPVLDERSYYNSGVDYNFSREKNGLGAFTPFEKQDVFNIPDEILHEFSTSQTKTDMGIFPELNRCWITIDNKLILWNINNDNEYQVVDDMKHTIQKVALVRPKPNTFVPAVKHLLLISTTMELFMFAISLDKATNELSVFNTHLSVPVQGIDVIDIVSHERSGRIFFAGQASGLNIWELHYSGSDDWFNSKCSKVCLTKSALLSLLPTNMLSQIPGVDFIQALFEDNSNGNGGFSQETITQLTIDQQRGIIYSLSSKSTIRAYVITEKSLEGPMSIEPAYISRIIGTTTARAAPILGPKYLKIVKISSVAPEENNNLFLVALTVGGVRLYFNGSMGRFNIEALRLESIKFPPSSVTPEVIQQELLHQQQEQAKRSFPFFSNLMSSEPVLLKFQKKSSVLLETTKASTIISPGIFFSAVIKSSQQTHQQEKKENSSVTGTTATAGSKTVKQQPVTLQHKLFVSVPDYGILKTHGKYVENATFLETAGPVQQIIPLSGLFNATTKPQGFANEFATQYTSETLRVAVLTSTSIEIYKYRTPDEIFEDLIDNPLPFVLNYGAAEACSTALFVTCKSNKSEKLRSNALTFLTMGIPGVVDIKPVYNRYSVSTVSSLLSKPTLSTATTNLQQSITGFSKPSPANKEDFDLDDVILSPRFYGIALLITRLLRDIWGRHVFMTFTDNRVTSHAFISSSDPITPSINNLKSDEISQNRNIISKVSISKDCIEYYLSSINILNEFFITYGDSISQISAPYVLANNSNGRVIDKTEEVANQAESIAINAMIKMVQSIKEGLSFLNVLYEESEVEGFDNQYLGFKDIISFVSLDVQKDLVKLDFKDLFAPNDKTKSLIREILLSIINRNITKGASIEYTATALQERCGSFCSASDILGFRAIEHLRRAKEIGLRNYDSLNYHLKNATALLEQIVDDLSIEKLKEAVSMMLSVNYYPKSIEFLLNIANSMDKGKLACQYVANGFLENDDRKQYYDKRILVYDLVFDTLIKVDELAEKKQSSKTQNQISISNDDEVKLRQKSYEAALKYNDRLFHYHMYDWLVSQNREEKLLDIETPFILPYLMEKAGSSLKISNILWVYYSRRSKFFESAEILYRLATSNFDITLFERIEFLSRANGFCNSVSPLSQKQRIVQLASRIQDACEVAGIQGDILSLVYTDARIDSAIKDELIKTLDGKILSTSELFNDFAVPLSYHEIALFIFKIADFRDHEVIMAKWDELFQSLRMEFNNTGKKEDSMNFINLLSNVLIKIGKNVQDSEFIFPIFELFPIVCNFFYETLPKEHIVSGSIVSIFITAGVSFNKMYYILKELIETSDSDNSVFNKEMTWLIHEWYKSDRKFRDIISYNDIIHLKEYKIDNDPIEKYVKNSGNNLGICFYKE
The following text describes a protein:
Function:
NAD-dependent protein deacetylase.
Sequence:
MEKDLGEEKDQDQEQNTEMEPKQEMDVAQSYITRAKMNPAKKDNEKRRRKDAMRRVSMILRKCDSMRTTEDRQFLEKHPDMVKTTKKRKERVEIYKERVVEREDAPHVIEAKVEQLANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLQKGQDIGEHDLSSANPTYTHMALYELHRRRLLHHVVSQNCDGLHLRSGLPRNSLSEIHGNMYVEVCKNCRPNSVYWRQFDTTEMTARYCHKTHRLCHRCSEPLYDTIVHFGERGNVKWPLNWAGATANAQRADVILCLGSSLKVLKKYTWLWQMDRPARQRAKICVVNLQWTPKDAIASIKINGKCDQVMAQLMHLLHIPVPVYTKEKDPIFAHASLLMPEELHTLTQPLLKNADEEEAFTTTTEETQDSTISSESCSFNYSDLPIGKGPRIRTPIKNGRRVKTNLELRQKFKTLNGQDEEIKVEHVKTNGEVKTEKDLITLESSIKIETEVKLEKLECSDTNFQQELKLLELLPKLEPLSLKEETEETPSNGFPELPKLVAIQKTHAECLSAVPTESRLKPLQLPPLVPIGAPLSTPFVEPKLVLPPASQSSSIQIKSEGDGDSSTENDNEEEEESELAQMDLLRQNNDEELLRQLPTWYDAKYAYSGLHSILIPPPADLNIWNSQVVPNFAMNRSAASCFFCFDRYAELECQFYRRWNLSQRKHKKRARSGRFVVCECCPTSDDDDDYDENISLAHIAAAETAKRRQQLSTSFPRKLARTQAGWYGKGYKKGRKRR
The following text describes a protein:
Function:
Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSFRGGRGGSFRGGRGGSRQPMSYGPPDQVLELGTFVHDCEGDMVCESTNPKIPYFNAPIYLENKSQIGKIDEILGPMNQVYFTVKPMDGVVAGSFKPGDKVFIGGDKLLPLERFLPKPKVAGPKKPKTAGGRGGRGGFGGRGGFGGRGGFGGRGGSRGGFGGNRGGFGGRGGSRGGFGGRGGFNNRGGSRGGYGGRGRF
The following text describes a protein:
Function:
Probably involved in translation.
Sequence:
MSDLDLQVPAAFDPFAEANAENSGAGTKDYVHIRIQQRNGRKSLTTVQGLKKEFSYNKILKDLKKEFCCNGTVVQDPELGQVIQLQGDQRKNVSTFLVQAGIVKKEHIKIHGF
The following text describes a protein:
Function:
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSLIKKKNKDIRIIPLGGVGEIAKNMYIVEVDDEMFMLDAGLMFPEDEMLGIDIVIPDISYVLENKEKLKGIFLTHGHEHAIGAVSYVLEQLDAPVYGSKLTIALIKENMKARNIDKKVRYYTVNNDSIMRFKNVNISFFNTTHSIPDSLGVCIHTSYGAIVYTGEFKFDQSLHGHYAPDIKRMAEIGEEGVFVLISDSTEAEKPGYNTPENVIEHHMYDAFAKVRGRLIVSCYASNFIRIQQVLNIASKLNRKVSFLGRSLESSFNIARKMGYFDIPKDLLIPITEVDNYPKNEVIIIATGMQGEPVEALSQMAQHKHKIMNIEEGDSVFLAITASANMEVIIANTLNELVRAGAHIIPNNKKIHASSHGCMEELKMMINIMKPEYFIPVQGEFKMQIAHAKLAAEAGVAPEKIFLVEKGDVINYNGKDMILNEKVNSGNILIDGIGIGDVGNIVLRDRHLLAEDGIFIAVVTLDPKNRRIAAGPEIQSRGFVYVRESEDLLREAEEKVREIVEAGLQEKRIEWSEIKQNMRDQISKLLFESTKRRPMIIPVISEI
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MPPKLGLALPLLIASVTSPRPGEATAGNVIKKANWQAICKVTADAGNLAGLALTNIRAPGLQVAADIKALLRTLIYIEGNSTSAATKVQGKAAAFLAGQTAENLEYYSSTSVATDVTTARDAGRLHGATHEFMSVQADGSTSANGCIGDNESGSNALAGFSAVVEANPNCQLSWETVTTYDGTVTAITKTGLGGKFANAIAHNKFTSGDRKCNINSAASGFKLNNDGTSVDTSGNKPKMAAGIISLDAANGIRTIALANVMGDDEHPYLKAAATAAKRSKQTPKAADLTTADTALASTDFKKAARRHILGKKETADDSDTTLAAKVKKAFGSDESINKLISTNVNNMPIAGILTDNTDAKSLGQITDISELVRLYFYYSDLNKQKLADTAKKPREAEAKTATKSAEEKEKECNTKGKDKQDGCEKLKDQGCVFNKDGDRDKKCTLSKEGKKEAVKAAESKETNKDGKTNTTGRNSFVIKDSPLWLAFLLFN