lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May act as a carbohydrate transporter.
Subcellular Localization:
Endomembrane system.
Sequence:
MKMGKGMIFIVALVAICLGGKWVEAQVHHVVGADRGWDQTSDLVSWAAGRVFRVGDQIWLTYSVTQGLVAELKSKEEYEACDVSNPIKMYTEGLHTIPLESEGMRYFVSSEPENCKNGLKLHIEVLPKADERIIESSTLTDEAVAPTTPSGSARYGHNTMLMLTVILFVVIGLAY
The following text describes a protein:
Function:
Involved in prephenate-dependent formation of 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs, the first step in 5-carboxymethoxyuridine (cmo5U) biosynthesis.
Sequence:
MTTQFKPELLSPAGSLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFNHANLKIGIDEAHSLGKKFYVVVNIAPHNSKLKTFIKDLQPVIDMKPDALIMSDPGLIMLVRENFPNIDIHLSVQANAVNWATVKFWKQMGLTRVILSRELSIDEIAEIRQQVPDIELEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYKMEEGTTDDVGNIVPKIDPAQQIEVKNVAPTLGEGAVTDKVFLYTESQKPDEQMTAFEDKHGTYFMNSKDLRAVQHVEKLTALGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDESLMDTLESLAHRGYTEGFLRRHTHDEYQNYEYGYSISDRQQFVGEFTGKRNEQGMAEVAVKNKFLLGDNVEMMTPQGNINFKIEKMLNRKNETVDAALGDGHFVFLNVPQDINLNYALLMRNLVNTNTRNPHSN
The following text describes a protein:
Function:
Uptake of xanthosine. Can also transport other nucleosides such as inosine, adenosine, cytidine, uridine and thymidine. Transport is driven by a proton motive force.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSIAMRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVYSSKGIAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGVLFYAASVTDPDMMFWVMLVNAMAFMPTIALSNSVSYSCLAQAGLDPVTAFPPIRVFGTVGFIVAMWAVSLLHLELSSLQLYIASGASLLLSAYALTLPKIPVAEKKATTSLASKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAYGDPSTTGFILLLLSMIVYGCAFDFFNISGSVFVEQEVDSSIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFSVDGVKDWQTIWLVFAGYALFLAVIFFFGFKYNHDPEKIKHRAVTH
The following text describes a protein:
Function:
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MGHKEEDDCSSWKKQTNNIRKTFIFMEVLGSGAFSEVFLVKQRMTGKLFALKCIKKTPTFRDSNLENEIAVLKKIKHENIVTLEDIYESSTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPTERYTCEKALRHPWIDGNTALHRDIYASVSLQIQKNFAKSKWRQAFNAATVVHHMRKLHMNLHNPKAVPEAGNRLPVVQGSETPRPSGPVVSVPKASNPDKNALLPMMPRMACQHPVLLPAPGDAVSDNRSVNCLVNGSLQISSSLVPMHQRPLSGSPCSCCSNCLKSSEKGKASFCSEPVLLKKTAKKQHYKSEVIVPVKASAHSHCRGGQTGVCLIM
The following text describes a protein:
Function:
May be involved in defense responses monitoring. Probably implicated into osmotic stress signaling.
Sequence:
MGKGGNYVTVAASEVDELRRKNGEMEKAVEEMKKEMLQLWRRTQVAEEAEERLCSQLAELEAESLDQARDYHSRIIFLMNELSRLSSDSASASP
The following text describes a protein:
Function:
Transporter for the divalent zinc cation. Mediates the influx of zinc into cells from extracellular space. Can transport divalent iron ions. Does not transport manganese and cadmium cations.
Subcellular Localization:
Plastid, apicoplast. Cell membrane; Multi-pass membrane protein.
Domain:
C-terminal histidine-rich loop acts as a negative regulator for Fe(2+) binding and thus determines selectivity for Zn(2+).
Sequence:
MDLLFAKIICIGIFLVVTTFGCFIPHLMGLYKEKENEEKNKRVKNILSNLNCFGSGFIFSIIMFHLLPETIHIISDHGNIRIFNTSDSQMKILYIFFFVFIGFCMQLGLEYVLPVDTNICCVSNLDSKKKLEDTLSQHITKNASTTVNIEMQNIDNIDHIHEHSCEGVHTHDEKSIGKFLEILTLQSFFLTISLAIHSCIEGMIIGTSTDVNYVFISSFCILLHKWIAGVTVSLSLNSNNMNKTLKAILLLTFVFASPLGIVLGHMAKSAGQKVTCLINAVSIGTLLFIGCEILLNEIKQNISRKVRLCKWLSFCFSCLIAFALISFTTSMAPHTHGDIDTHVHVHHHDHDHDHGHNH
The following text describes a protein:
Function:
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
Subcellular Localization:
Cytoplasm.
Sequence:
MVAKLEQLIAQTILQGFDAQYGRFLEVTAGAQHRFEQADWHAVQQAMKKRIHLYDHHVGLVVEQLKYITDQRHFDVEFLARVKEIYTGLLPDYPRFEIAESFFNSVYCRLFKHRDLTPDKLFVFSSQPERRFREIPRPLARDFIPKGDLSGMLQMVLNDLSLRLHWENLSRDIDYIVMAIRQAFTDEQLASAHFQIANELFYRNKAAWLVGKLRLNGDIYPFLLPIHHNESGELFIDTCLTSKAEASIVFGFARSYFMVYVPLPAAMVEWLREILPGKSTAELYTAIGCQKHGKTESYREYLAFIHQSSEQFIIAPGVKGMVMLVFTLPSFDRVFKVIKDQFAPQKEVTQARVLECYQLVKEHDRVGRMADTQEYENFVIDKHRISPELLAELQHEVPEKLEDLGDKIVIKHLYMERRMTPLNLYMEQADDQQLKDAIEEYGNAIKQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDEMASEPWYSVSPNDVFPEEFRHFLCSDRKVRHFFEEMHGDLFQASYWRGLQQRIRDGHVEDVFAYRRKQRFSQRALN
The following text describes a protein:
Function:
Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQQPGAGGAAQGREGEGKGPGARARPQEQPAGLAARDESGQTRCAEPPGAQRPADRMEEPPFEAHEIQQDSDSLTSLESSVFCSEEEVESLGLGEGPSLDCFIVNVGGSRFVVSQRVLSCFPDTRLGKLAVVVSSRRPPGAPAPASTLELCDDANPVDNEYFFDRSSQAFRYILHYYQTGHLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKNDNDDQESQQESEQDFSQGPCPNSRQRLWDILEKPRSSTAARIFGTISIIFVIMSIANMALMSTDFGWLNPQLLEGLEYLCITWFTGEFALRLLCVRDRCHFLRKVANIIDLLAILPFYITLLVENLSEGETTQELENVGRIVQVLRLLRALRMLKLGRHSAGLRSLGITITQCYEEVGLLLLFLSVGISIFSTVEYFVEQSIPDTTFTSVPWAWWWATTSMTTVGYGDIRPDTTMGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSSISVNLRDVYARSIMEILRLKGRERASTRSSGGDDFWF
The following text describes a protein:
Function:
Sodium-phosphate symporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MGTLSTCKLDVNTTLPLVCICTLLSFLCGVGIGANDLSANFAMVVGSGSLNMKQAIIYCTVFELLGAAFMGGHVSKTIRSGIVDPVLFSQNKDVVVIGMTCASFASALWLYLSAVFGLPVSITHTVVGSILGFALFATGGLTYVKPSGVVAVVISWLAAPIAACGVTALLFYFMRRDIFKVRGRSFELARAVLPHCLLASLLVDFFFIVLEQPPIMSQTLAQNVPLHVQYAILLALILLFCWVAQVWVFPQVAAAAMSARSFVWESEALRTEPVSMEDGLALGDLKDLSFFKSRGDVSATAPVSAGRQPPRPHHRHQPPAGATDTAPVAVPAAVALPPPSLPDDPAPVCTLDSLSLDRRNDGAADHDSSESSFTYGCPTHSRSPTPTPLHQNASLVLSSISASDSPFVRKGGMVRLAPVHTRGHSPTLQPHTESFATAAAPIQHGAKDAHHFLGCHVASSDRERHEAQQVQSAGVTTYGSTESKKPALVTCRGERGLVQIPYSPALVQSEDEFGEEDWAMDHPMQPIRFGGILIKPFNPRAEYLFTGLQVVAGSISSFVHGAVAGANATSAFVILYDAFTNHELQEPGLSSQWSMLPAMLGIAIGMFGLGASLMKTVGMELVTVTPARGWCIQIGGTLVTMVLTGIGIPVSLSQAQVGAAIGCGVLDAKLGGVSWGIVAKVVTGWVVTLLISALTTGVSMWVVSSLLCT
The following text describes a protein:
Function:
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
Subcellular Localization:
Cytoplasm.
Sequence:
MAIPVVVVGCAGKMGREVVKAVHAAPDMAVVGAVDRSHIDEDAGELAGIGPIDVLVTDNLEITCAMVAQERAPGVMVDFTHPRGIYDRVRSAIAYGVRPVVGTTGLPPEHIEELAEFADKASTGCIVAPNFAIGMILLQQACLRAAEYFDHVEIIELHHNRKADAPSGTALATAQMIATTGKTFNVPEVSESELVAGARGGMTPGDIRIHSLRLPGLLAHQAVIFGGLGQSYTLRHDTTDRAAYMPGVLLAIRKVLGLKSLVYGLEKII
The following text describes a protein:
Function:
May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression.
Subcellular Localization:
Nucleus.
Sequence:
MDFISIQQLVSGERVEGKVLGFGHGVPDPGAWPSDWRRGPQEAVAREKLKLEEEKKKKLERFNSTRFNLDNLADLENLVQRRKKRLRHRVPPRKPEPLVKPQPQAQVEPVGLEMFLKAAAENQEYLIDKYLTDRGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLDILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLYGAELGVRNAASVTPVQLARDWQRGIREALQAHVAHPRTRC
The following text describes a protein:
Function:
Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSSNKTEKPTKKRLEDSAKKGQSFKSKDLIIACLTLGGIAYLVSYGSFNEFMGIIKIIIADNFDQSMADYSLAVFGIGLKYLIPFMLLCLVCSALPALLQAGFVLATEALKPNLSALNPVEGAKKLFSMRTVKDTVKTLLYLSSFVVAAIICWKKYKVEIFSQLNGNIVGIAVIWRELLLALVLTCLACALIVLLLDAIAEYFLTMKDMKMDKEEVKREMKEQEGNPEVKSKRREVHMEILSEQVKSDIENSRLIVANPTHITIGIYFKPELMPIPMISVYETNQRALAVRAYAEKVGVPVIVDIKLARSLFKTHRRYDLVSLEEIDEVLRLLVWLEEVENAGKDVIQPQENEVRH
The following text describes a protein:
Function:
Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space.
Sequence:
MTARGAAGRCPPTTWLGPLLLLACLLVSNGATEEVSENCSHMIGNGHLLFLQQLIDSQMETSCQISFEFVDQEQLDDPVCYLKKAFLLVQDIMEDTMRFKDNTPNAKVIVQLQELSLRLKSCFTMDYDEQDKACVRTFHETPLQLLEKIKNVFNETKNLLKKDWNIFSKNCNNSFAKCSSHDVVTKPDCNCLYPKATPSSDLASVSPQQSPTPSTAPMAGLTWADSEATDGSSLLPREQALRTVDPGSAKQRPPRSTCQSFESPETPRVEGRPTGDSPQPGPSVGAPVTGMEDVLDSLLGANIALEEASGEASEGPIPQGAELSFYSLGGRSVQAEPASPSHTPPASSALSGSGKGLRLVDATSAHLPTLGPMRPTEAWSHTPEKTERPSASPRDHQEPDMAKTPALHPQGLSSPSALSSQPKLPRSHSWGHVLSLGELEGRRSTRDRRSLAELKGGQASEGAARPPARFNSVPLTDTGHERQHKEASDPQLPGFVFRLLVPSIILVLLAVGGLLFYRRRRRSHQEPQMVDSPMEQPEGSLLTQEEDRQEELPV
The following text describes a protein:
Function:
May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
Subcellular Localization:
Mitochondrion.
Sequence:
MALPGARARGWAAAARAAQRRRRVEGAGGSPSPEPAGRRAALYVHWPYCEKRCSYCNFNKYIPRGVEEAAMQKCLVTEAQTLLRLSGVQRVESVFFGGGTPSLASPHTVAAVLEAVAQTAHLPADSEVTLEANPTSTPGSRLAEFGAAGVNRLSIGLQSLDNTELRLLGRTHSACDALRTLAEARRLFPGRVSVDLMLGLPAQQVGPWLGQLQELLHHCDDHLSLYQLSLERGTALFAQVQQGVLPAPDPELAAEMYQRGRAVLREAGFRQYEVSNFARNGALSTHNWTYWQCGQYLGIGPGAHGRFMPQGAGSHTREARIQTLEPDNWMKEVMMFGHGTRKRVPLGRLELLEEVLALGLRTDVGITHQHWQQFEPQLTLCDVFGANKEVQELLEQGLLQLDHRCVGGCQAEGAEASQGALTTALHRPRRSEKD
The following text describes a protein:
Function:
Regulates telomere length and function. Required for the repression of telomere-adjacent gene expression and for normal meiosis or sporulation. It may be a negative regulator of the telomere-replicating enzyme, telomerase, or may protect against activation of telomerase-independent pathways of telomere elongation. It may be involved in the interactions between chromosomes and spindle proteins, disruption of these interactions would lead to defective meiosis.
Subcellular Localization:
Cytoplasm. Nucleus. Chromosome, telomere.
Sequence:
MISVQSTETIQKVLENEGDQQFDKEVVQNSDSNIETGQISDSLTKAVEERAETESSSNLSNFTTSESESSKPAYCFNSHSQNMAEGSISIPVISHSMNVENEVSTAEGQDSRTGESENDQNAMIVRSIWDIEKASLLVNDCQNIANMAEQKVMMVSAIFSESSKDIVNPESFSERLGKETVKDLYEFNEQLTTKYGLEFRTIFFSYIRKYDAYWCLFEDLEKPLKSIQFFTGLIDLLDNTNKHLTLRSIVLDALLSADEEDSFYGDALVLFEELVIRYFGTDSNPSIDASEFILSCLPYTSLDALNVVCGQVWKSQKICDFLKSTIGNTSNSPLQLRASFPAFVNAVIHFLLEFKNVRRLERKDLSVKGMLYDSDSQQILNRLRERVSGSTAQSADEASGHESDASEDTFSERTLGLNSIDNTEISEVVSLGLVSSALDKITGLLSADNLSETVSQARDFSHTLSKSLKSRAKSLSQKEAANRSKLIAKRGDNLRREASLSSEQDDLSEDFPPVRESDEQESRSGGRSSAMRVSIERSAARSGTRRSQGNPYEGYRTRRKWTDEEENELYEMISQHGCCWSKIIHIQKLENGPLKTFGPTQIKDKARLIKARFMKQNRLQELYSKSLNWKNVTVGQAYCELHKIPYIEATPPLLREELVNYQS
The following text describes a protein:
Function:
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
Subcellular Localization:
Cytoplasm.
Sequence:
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASIGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
The following text describes a protein:
Function:
Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPAAIRPMKKTVSFSKDVSNNNNNLESDSDTKQSPQSYLTFIPQIKNSLLVVPFHNIFILVGMFYSGLTQDLETVMWKGFLTSIPIQVIYNYIIYINLLPLKKSTRNDHQNNSSGSAINNNNNNNNNNVPLLIGSSIFVSIVLSLPLFVVIILMGAPVYKYSLKTLYLSLHLSQLIFNPLIILSNLNVNKIKRLFKQDHLYRIIFHHGILSSVLLTLGGCWLGVIPIPLDWDRPWQQWPITLLVGGYLGGVVGGVLSLIVNYFSH
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically binds GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum. Golgi apparatus, Golgi stack membrane.
Sequence:
MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYCADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPSFEPPGPGSYENLSTGTGESKPDALGGKQETSADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
The following text describes a protein:
Function:
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSSGLGTNTMNVVIDAAHLLWDVCRHILLSGVKWVVKPEEKSIMDDICLITGSGGGIGKHFALEFAKKGAILVLWDSDPECNEETAKEVRRLGARAFTYTCDTGDRQQVYQVAERVRREVGDVTILLNHPSTGTGKSLLHCQDEELENALRTNCLANFWTVKAFLPRMNQMNHGHVINVASYLGLFATANMEDYCTAHFATVGFHEALSHELKARRISGVKTTLLCPYLADIEMYSSFKIRKDLATLFTPLTSEYFARRAINGILTDQPMICMPKLLYLAAFLKQVLPWEVQELCHSLIRNREKPAGTQSHYSNQG
The following text describes a protein:
Function:
Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MASLLGTSSSAAAAAILASTPFSSRSSKSAVLSLFPSSGHSQGRKFYGGIRLPVKKGRSQFHVAISNVATEISPAQEQAQKLAEDSQRPVYPFPAIVGQDEMKLCLLLNVIDPKIGGVMIMGDRGTGKSTTVRSLVDLLPEIKVISGDPFNSDPEDQEVMSAEVRDKLRKGEQLPVSLTKINMVDLPLGATEDRVCGTIDIEKALTEGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISISHPARFILIGSGNPEEGELRPQLLDRFGMHAQVGTVRDAELRVKIVEERGRFDKNPKEFRESYKGEQEKLQSQITSARSGLSSVTIDHDLRVKISKVCAELNVDGLRGDIVTNRAAKALAALKGRDKVTPEDIATVIPNCLRHRLRKDPLESIDSGLLVVEKFYEVFG
The following text describes a protein:
Function:
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.
Subcellular Localization:
Golgi apparatus lumen.
Sequence:
MAFLLVSAYLLLTRSHSAPVENGALMETLKSQVLLLSNKSEHYSTQVRPPGTSRRIPQTIIIGVRKGGTRALLEMLDVHPNIVVAATEVHFFDWDENYVKGIEWYRSLMPFSYENQITIEKTPGYFTSPQAPERIHDMNSSIKLLLILRDPTERVISDYTQVYYNRLESHKPVQLFEDIVIKNGALNTKYKAIQRSLYDIHMERWLKHFHLDQIHIVDGNTLIKDPLPELQKVERFLNLPSRIMSSNFYFNQTKGFYCIRSDGRERCLHESKGRPHPIVNSTVLEQLYSYFREHNAKFYRMIKHSFDWH
The following text describes a protein:
Function:
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
Sequence:
MAEIMTALIICEKPSVAKKIANALGKAKKKSIDGVPYYELERDGKKIIVASAVGHLFTLVEKENKEFGFYPVFDIKWVPASVDKGKEYVNKYIKALKKLSKDADEFYIATDWDIEGELIGYHALKYCCGREKAKRMRFSSLTKKEIVRAFENPDEIDYGLVDAGESRHILDWYFGINLSRALMNAIRAVNRWKTMSVGRVQGPALAFLTERELEIKKFIPKPYWVIEALLKDNLKAIHEKEKFWNEKEAKNVYEKIKDEKSAKVVEIKKTKRKLKPLPPFDLGTLQREAYSYFKISPKETQEIAQKLYENALISYPRTSSQKLPKDRKYLEDILNIIKNHPVYGKWAERILKENLKPVEGKKEDPAHPAIHIVDIPKEELSEKEKEIYDLIARRTLAAFWDNAEREYLNVKIDIKGEKFKLSGSRTVKEGWHEIYYFPKFDEIELPPLKKNDIIKVEKITITRKETQPPKRYTVASIIKELEKRGLGTKATRAEIIDKLIKRGYVIDDGSLKVTDLGISVIETLKRFCPEIIDEKMTRDLEEKLEKIQFRKIKKDDVLDEAEKRLRKILEEFKKKEEDIGIYLIKNLDATNKKAKIVGKCPKCGGDLILIRHKKGRFVGCSNYPECDVKYSLPDKGRIKIPNKVCDACKSPILKIGDREICINPECPLKQVEVKEEDRICPKCGAKLILKKGVYGAFYGCSNYPKCKYTEPINKKEVVGKCPKCGGDLVVREGKFGKFVGCSNYPKCRYTEKLKLNEKEEK
The following text describes a protein:
Function:
Involved in the endoplasmic reticulum-associated degradation (ERAD) pathway that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. May initiate ERAD by promoting the first mannose trimming step of ERAD substrates, from Man9GlcNAc2 to Man8GlcNAc2. Seems to recognize and bind to exposed hydrophobic regions in target proteins.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MQLPEEKKITRKIICSKRPPRALVVLVWCCTTGLIFRLVSEAHGLRKFSSSDMYRMREKVRQMFQHAYDGYLQYAAPYDELRPLSCDGIDTWGSYSLTLIDALDTLAVMGNYTEFGRVVQMLQGRSFDADINVSVFETNIRIIGGLLSAHLLSNHADLKSMGLVEPGWPCQGPLLDIAEEVAQRLLPAFDTATGMPYGTVNLRHGVPYGETTVTCTAGIGTFILEFGTLSRLTGNPVYEDVAMNALSALYKHRSPIGLYGNHIDVQTGRWIAQDAGIGAGVDSYFEYLVKGSILLENPALMATFFESKASIDRYLKREDWYVWVSMSKGQLTLPVFQSLEAYWPGLLTLYGNTKEALKVLHNYQTVWRQYGFLPEFYNIPTGEAGANRENYPLRPELIESVMYLYRATSDPFLLQVGENILESIEHSAKTPCGYATIRNVLTHQQEDRMESFFLAETTKYLYLLFDPNNVLHNDGSIGNVVKTILNDGVTKEHKCVVGAGGYIFNTEAHPMDPTALRCCEARHINIFANALVENQMNKKERRGKLLFAKGQQYLSNTKNRQDKKNEWMITEPKEPPKMTDVKIELKGGEKMATTKLPINTINREIEETESVSRGIKTKNMYSSESISNSNHMKSIKEQFSQSFKDEINHATAFSLLPVDKATTNAASSNKAKSSSTKKVSEILLMKKSEEEFTPVTVQSYSTTGYSASTKDKNGNEEDTPMATMLKLVQSMFHTTANLAQKRSVFDLENFYQQVVNNRLLNDESGNFNISGMSSPSYNKEKILNGLLTCRSQPFLQRLTLIGEFY
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.
Sequence:
MFGLGTQELLIILVIVIVLFGATRLPQIGRGIGEAIKNFKKATSEKDEIDVTPKKDNTEEKK
The following text describes a protein:
Function:
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Miscellaneous:
MISCELLANEOUS: Lacks the C- and N-terminal parts of classical GPI inositol-deacylases and may not have GPI inositol-deacylase activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MWVAYSPIEGLTTEHSRLAEKYSLYLVKSTPYDIPLPVRPSGVPVLFVPGNAGSYRQIRSISDTCRELNEQYGGSEIDFFALDFNEAYSALHGRTLLDQAEYLNDAINYILQMYRDNGKDVSSVMLLGHSMGGVVSRLAISLDNYKPGTVTTIFTLASPHLVPPATFDGDIQKVYNRMNDFWRSNYADSDNNSLSDMTVLSIAGGKRDTMVPSDYISLDSVVPSSHGLSTFSNSINRVWTGIDHDAMMWCHQLRRQIAIALMNVIDRDVNGRMEVFRKVFSGTQTLSDAEEDFEDVEVTPVKHGLHQKLESGWYYGENVQVMTTHTVNQESAFESYEMSSGSLLRAFECRSKSGSSFKGCRKIFPLLVPGSNDAVIAFAETEHYLLLDVSSSSDWISIDQVSQKSASFDFVTGATISTSNTISTDISFPKLTSGLVSYKVSVSKGVQLVRQYVQQNSSRVYDSKYLVPHNGVVDVSFHGDVPFVPYFQSSPLHLQVFGGGHVTIRVDWIGSLGNLFMRYRILFISLPSAILYAIFLVQFHAGTARFLSLRQSTSIFINRYLLTSCLAGSGIAYLTGLSQVRDFLHLIQIPITKTFAVDPSYTKNDLFLGLSGVSGTVLAPIFTVFSTGMVVLITELVMGLTSLLSFCFKSTTTAQSESESGDPISDLLHKRTVFVAVISVLVLLFFPYQLAFTLATVALLVMTAYFKSNKAPQEQSFNNYISTICVLMTWTCIINAPVLAVWIQGIVVQRSMTFSSHHNLVSILPTLLFVENLSFRRIPSGSSITSLLLAYTSLHCLFYGMMQAFMIHHGFNLLATWLLCMSYKKVFFKSKHE
The following text describes a protein:
Function:
Lectin involved in innate immunity. Agglutinates all types of human erythrocytes, Gram-positive and Gram-negative bacteria. Has a stronger agglutinating activity towards Gram-negative bacteria than towards Gram-positive bacteria. Specifically recognizes acetyl group-containing substances on agglutinated cells. The hemagglutinating activity was inhibited by EDTA, acetyl group-containing mono- and disaccharides, N-acetyl derivatives of amino acids, other acetyl group-containing substances, propionamide and benzamide. Enhances the antimicrobial activity of big defensin against Gram-positive bacteria but not against Gram-negative bacteria.
Sequence:
MDLKVQFVLIFLLAHKVSLEKYEFLKFSVRNNKNRINELEEQVQEIWDYINSTQVVKASKNNVPKSCKEVLDSGRNISGVYNIQPKNTSQSFMVFCNMELKDGGWTYFLNRFDGSVDFYLDWEDYKKGFGNVNGEFWLGLQHLHELTSDDGKNELLVELVDWNNTKAYAHYSSFAIGSEDEGFSLKVLEGFSGDAGDSLSVTKGMKFSTRDKDQDEGDANCAQLFGGAWWHKNCMAALLTGKYMRETVELDQKNKVMYWYTFRGTQYSLKEARMMVKPKTSS
The following text describes a protein:
Function:
Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.
Sequence:
MHPRVLEVTRRIQARSAATRQRYLEMVRAAASKGPHRGTLPCGNLAHGVAACGESDKQTLRLMNQANVAIVSAYNDMLSAHQPFERFPGLIKQALHEIGSVGQFAGGVPAMCDGVTQGEPGMELSLASRDVIAMSTAIALSHNMFDAALCLGVCDKIVPGLLIGSLRFGHLPTVFVPAGPMPTGISNKEKAAVRQLFAEGKATREELLASEMASYHAPGTCTFYGTANTNQLLVEVMGLHLPGASFVNPNTPLRDELTREAARQASRLTPENGNYVPMAEIVDEKAIVNSVVALLATGGSTNHTLHLLAIAQAAGIQLTWQDMSELSHVVPTLARIYPNGQADINHFQAAGGMSFLIRQLLDGGLLHEDVQTVAGPGLRRYTREPFLEDGRLVWREGPERSLDEAILRPLDKPFSAEGGLRLMEGNLGRGVMKVSAVAPEHQVVEAPVRIFHDQASLAAAFKAGELERDLVAVVRFQGPRANGMPELHKLTPFLGVLQDRGFKVALVTDGRMSGASGKVPAAIHVSPEAIAGGPLARLRDGDRVRVDGVNGELRVLVDDAEWQARSLEPAPQDGNLGCGRELFAFMRNAMSSAEEGACSFTESLNGWR
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion outer membrane.
Sequence:
MSAAASNSSKMMTSPGDMFTLENPVFCCYLFWSTVLVVKMLLMSLLTAVQRFRYKIFPNQEDLFFKNLEVQFDDPHVERVRRAHRNDMENILPYFIMSLIYISTNPNADVACILFRVASVARIIHTLVYAVYPVPQPSRILAFATMLLITFYMAAVVALRTLSFI