lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MGAPRSGPGGVRVGALLLLGLGGLVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPNYEFYKLYLVGGAQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAAPRKPVSEMPVERDRGATHSLEPGKENTAGDPSSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV
The following text describes a protein:
Function:
Receptor with an affinity for galactose and fucose. Could be involved in endocytosis (By similarity).
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVVQQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN
The following text describes a protein:
Function:
Required for nuclear migration within hyphae during vegetative growth.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Localizes to the plus ends of microtubules.
Sequence:
MAADVPGSPLAKNATTEEALAWYKSQYEELEQELKEFQQSSKELEAELEKDLDAADKRERALQQKAEGLSYEVEEWKRKYKESKSEANAAQSALEKEITALRETNRTLQLKLRDIEVANDDFERQARNTSSSLEDLESKYNVAIERAVMMEEEIKIGEQERERLRVEAQRLREELSDLKIEAEILQSKLRKHQARGHLTQITTTIAPAPASPLSTASSPLVSTPPDTKSLSTIDTLSEVQDPPSPPMSDASLGKGLRASRSTPVKQTASRPGGCRTPKTSISKSAAAKSSAQATHKANQSFSENNITPKPKPLSSSTSSQSNRPSNGRFNTNSYPMVRTPSSRPSGARAAERPRAPVHRIPPSNSLTHIRTLTAQMQKLEARVHSARSKLPATAQTPPKQSPRFSGGIGGLAATVAMRGKKQRGVGASTSSLNLLDDDNASDISGTHSNPDFRSSTLNLSKHIPRLSTSGVSRIAFGPLPIRHPASAAASTTSTSTATATNVDSEVSRPSSRASSSGYGRPISRADSHSTAASGYMPSSSSRPISRTSLPGHGTRTPVGSWPRSSGNLSAYGHGPAHSQASISYSTAEEDELTDDGQRELRSKTTPARRRTGTLSARDAPDHHHTGIPIPGSGGNRRQSGSSSASRSSVTGSLSLRRQSNAAALGHGHGHNAGYGHGHGTVPGGTTVRKVVDLGETY
The following text describes a protein:
Function:
Involved in the biosynthesis of condensed tannins. Converts cyanidin into (-)-epicatechin as the major product.
Miscellaneous:
MISCELLANEOUS: Regulated by TRANSPARENT TESTA 2, TRANSPARENT TESTA 8 and TRANSPARENT TESTA GLABRA 1.
Sequence:
MDQTLTHTGSKKACVIGGTGNLASILIKHLLQSGYKVNTTVRDPENEKKIAHLRKLQELGDLKIFKADLTDEDSFESSFSGCEYIFHVATPINFKSEDPEKDMIKPAIQGVINVLKSCLKSKSVKRVIYTSSAAAVSINNLSGTGIVMNEENWTDVEFLTEEKPFNWGYPISKVLAEKTAWEFAKENKINLVTVIPALIAGNSLLSDPPSSLSLSMSFITGKEMHVTGLKEMQKLSGSISFVHVDDLARAHLFLAEKETASGRYICCAYNTSVPEIADFLIQRYPKYNVLSEFEEGLSIPKLTLSSQKLINEGFRFEYGINEMYDQMIEYFESKGLIKAK
The following text describes a protein:
Function:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.
Subcellular Localization:
Chromosome. Cytoplasm.
Sequence:
MARPARRRSSGRFLQQGESEPSLQKLVHMNDDAAEKQKRRQSKRLSILPGAVSLGSPGANAGEDVDEGLRDHLNNAAPQVPIMANFEEWMKMVNDNKINAQNSWNFALIDYFHDMSLLKEGDGINFQRASVTLDGCMKIYSSRIDSAATETGRLLTGLATKQGREDIGNEDDEEEGQEGEEGEGGEKKKKTVRPRGVTLAKSFEENAAKKLELELSIDPLFKKMCADFDEGGAKGMLMNSLGIDKNGRVVFDGDFDQEISKGDFADLSEDEDMEDDSADSFSLQQLGAKFFPDLSILATKSVCPSAAMIEAALKDPSNLPEGLQVDNLDDRPSMPELDYGGDEDILDDAALGDIGFDDLGAGGDDDGPGGPVEDFEFGYNPMNEQYAEIAQDVAIPGGVGPSDPRYKPTINEADLLAYFDHTLKKNWAGPEHWKVQKLRGDIQKKAIESRDNVGEDGEEGEEGEKADKTKKKAAPVEVDFISEDNDIDEAVLFGRPAHMSTLSLTKAQQRSDTNNLLPNDEHFSTDNLVKLFIKPGKRITGLLFKHRVTLQSEKDADQHFWAQHFNEELAEYGVQGPEPEPVDIPGQNDDGDDFGGYDDFDDYGGATDMGGPHNASFLGLPKAHPEYVSYAKVAKRVDVRKLKDNLWRVMDYEKVDELVDNGDMVEDAAKVEEKRFTQLVEQVGAEYPRQQKQEISTSFVFICLLHLANEKGLSIDQQDDLADLAISKDMNVRLDQLGA
The following text describes a protein:
Function:
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Subcellular Localization:
Mitochondrion.
Sequence:
MDSQLVNQLFRQLFRHHPACQSQKHLRHLATATAHNGHRVQQYHRRQQRRPYSSQRRGASSPVGDESQWQQRTKILNQDMTEEYKRAPMVTAAELWGRKQRPRRVKMLLRDFIEDSLYNPNYGYFSKQVTIFTPGEPFDFPNLRDETEFQNVLSQRYVDFEDKLDEVAPSDTRQLWYTPTELFRPYYGEAIARYLVANYKLTTYPYHDLIIYEMGAGRGTLMLNILDYIRDMDPDVYARTQYKVIEISDSLAKVQNSTLMRSAAGRGHLNKVEIINQSIFDWTQPVPSPCFFLAFEVFDNFAHDAIRYDLATETPMQAVVLISESNDFFEFYSPVLDPVAARYFRVRDAATGGRYKVPYPTTKLGKWVSSIRPLRSTMSEPEYIPTRLMQFFDVLSKYFPAHRLLTSDFHSLPDAVPGVNAPIVQTRYQRRPVPVTTPLVHQGYFDIMFPTDFRVSELVYQAITGKLSRVMSHEEFMRSWAYLEETETQSGENPLLKWYKNASVMYTV
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MARARRGRQNAAASPPSLALQLQVASLVIVFVFAFSSAITPTRADHVEGHMSHEMFGYENDATGPAKWGSLHKEWAVCGDGKKQSPIDITTVEPQKVKEPLMQAYKAGATTIQNRGHDYMLKWKDGNSKLTVQGKEYTLKQVHWHEPSEHTINGTRFDAEMHMVHEDPSMARAVVSVLLSTKAGQPNAVLTEVVTTTCLTVHLKWFVSISSPTERPRNGNEHI
The following text describes a protein:
Function:
May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC.
Subcellular Localization:
Nucleus.
Sequence:
MYFRMLRADPSRVAFCSWQIVILSMFIVSKCWLRSFGMAPSVYHSGGSSRQPKPVPYLLFPLDARFPWPMRLFHPVGRPCRSLRGSPSELQTFHQIQRRTRRHRTIFTEDQLQALEALFHQNQYPDVITREHLANRIHLKEERVEVWFKNRRAKWRHQKRASASALGLQGPKKPSEGSCL
The following text describes a protein:
Function:
Dehydrogenase involved in the conversion of monodictyphenone to the prenyl xanthones such as emericellin, shamixanthone and epishamixanthone. Monodictyphenone is first converted to variecoxanthone A via a paeciloxanthone intermediate by the consecutive actions of the FAD-dependent monooxygenase mdpD and the xanthone prenyltransferase xptB. XptB catalyzes regular O-prenylation at the hydroxy group of C-7 of the xanthone ring. Variecoxanthone A is further prenylated to emericellin by xptA before being reduced to shamixanthone and epishamixanthone by the dehydrogenase xptC.
Sequence:
MATDGMVLHKRSLSEGGTSTQAWKVLSQTLPSRGPDVDAWWQLTGRHLAVLLDAAAYPIEKQYECLLYHYHYAAPYLGPAPREGASPPTWKSMLQLDGTPFEFSWKWNNPGGEPDVRFGLEPIGPMAGTSLDPLNHLAMREILYKLSSAVPGSDLTWTHHFLATLFDHDYAKYTQKAATMGSSIGTSLVYSLEFQRKSTGLKTYFHPRKLDQQAFLDIPSWEASFRGLHPNSPSRTAVHEFLSTNPEGKLLKPFCLSVDNCSPAKARIKWYFNSPHTNFRAIREIMTLGGRIADTETRTKQFSELFNLLKTVTEEHADFPETSEFPYVPNNGDSIIPNFADAPDMLKGCVYFFDIAPGRNLPAIKVYFPVRNHCRNDLAVTQNLNRWLESRGRGQYGAAFGRALETIADYRRLEDSGGLLSFLSCQFMEDGELDLTSYFNPQAFHSGRLTHRRATRRRGDDRW
The following text describes a protein:
Function:
May be involved in the turnover of nuclear polyadenylated (pA+) RNA.
Subcellular Localization:
Cytoplasm. Nucleus speckle.
Sequence:
MPIENVEAFKTWLANTLSPICDADPQALAKYVVALVKKDKPQEELKALCKDQLEVFLQKETNTFVESLFVALNTKTYLPVHVPEPAPVPVTVPVPTPEPEEKKPEPIITHRKSEDVPDDDERDFRRVRKRSRSRSPHDRSRGRSGSAERDRKRYGDDDRPRRRDDYRPRGRERDYRRDYGRERRNYTSPDRRPHKDNPSSAPGEPPASDSPDGAKAPPPTYTTPSLSSTITVVSNDQPWMSQGGRGNFRGNDRGRGGFRGGRGRGGPPRPQRCRDYDEKGFCMRGELCPFDHGPDPVVVEDSSLPGMLAFPPASNGQQQGMPPIGPPRPPMSQAPPFSGGGPPPPQQGPPNMGPRPPMGPRGPRPPRPPMSQPPPATGEGGPRPPPPGPGGLAPPRPPPGPPPTRRTPPPPGTAAQRPPVPRGGPPPPPRYAQDMIRMPIMPTKHIRMPPPAPPPKNIRMPPPPLPPKREPFDPDGYNPELPGLDAGPVAQRPPYWSGGNNRNVNPTQTRALVSVPMVSTITTPKVEPQVSDTPSGHTRVVIDSGENRKRTFHQAMGPGSGPGMPYAGPPVKQGGHVRDRLGWKHTNCTLEIKKVPRDMNTVSKLSGYFERFGTVSNVQVCFDGDPESALVTFSSNAEARAAHQCTDAVLNNRFIRVFWHNKDQAQHHQGQSTPGEAPHHNPGPHRLSVRDRLYINPEHAKATGNSGPMSEKVHASSSGLSKTVYNPEAMKKVNTPQAAKQPSASQIAAQKVAEAQEALRKKQEEKKKEALKLKMNLQTKKQELLQKQIQQQKMLIERLEKNKGMAATERDAIMKTLKTVQESITKLKTDNPPKAATTAKPKTRQEDSRPLHMLQAQRELLDAEMDLLNAKTAGEDTTALKKRLAELQQEAQSLGLLNAGRGRGRGRGRGRGGVVRGRGRGRPYLRTRAGAVLDRRPKQLAITGYQIGDKDEILTHLSQFGEVEKVEYDETGLTLLLEFKTRLEAEIAATKGSIFKGTTLTITWNLPTRTVTLDHDDEGEVDLNDDEEDALLAPLPDDDEDDEDESESRSWRR
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MADTRARPWEADESSRSRDSKVPRLDLLAASAAEEEEKVKHLLGQEECTEMTGHDPCCDHVPTDSYHNDILISSLLSDDAGNCQDCRGRRREEADGPGGRPMYRRIMVCLECGRHSCGDSTSYIPYGHAQDHANQEKHWVAAMFDDPQAGFCFKCEHEVPVYPEPDEMEMITGEIQAGGGGGGGGHAFGFDMSRDLATVLLNLGDAWCAAADLGSVNAQGYAIRGMPNRGNTCYMNAMVQCLLALDKLRARMLGPDTPPGHLGMALKELFVEASAAGSAGGMLNPDKLLRSVRLHAGKYEPYTMHDSYELLESLRSALHDEEEGIQAPYRERGAPTVIDAVFKGELCDTRSCKDCQSASAFHGEFWELSLSLPSKEDLCENFASSSQRASKNLNPQPEKAAPQLLSANESNLWKIDASKTDSGEEQRTLQIKNLIHVLCTEEPLNSVDFVPHSIYDAKVEQMIQITADSLPPLIVPQVEHDASTAPGSYVDQNGKGIGEDSNCVLTIEDCLSLFFREEVVERSCDCSKVPMEEPSTNQSRKGKQMEVGTNDEVAANGSHSKQSDRTTCSNGQSSKLNSLSVEYNSCYCRQQHGSDEESDITQMADTHTAGANSRMTCGLKETEYHGGIQETVRSSSLSTEKQTDLLSTQHSQSLIPQNQDLRLDLSAHQLGDKQNGQKERSGRAIQRTNITKLPPVLTLHLKRYFKNGNEYHKNEARVSYKEHLDVGRFMNSSSADKSSTVYRLAGVVEHRGGPFMNAGHYVAYVRARKIGKQSSRPSSWFCADDSNVREVALEEVLERKAYVLFYERVEDANTLIG
The following text describes a protein:
Function:
Transcriptional regulator involved in the regulation of cell differentiation in meristems. Probably regulates the expression of various KNAT genes involved in the maintenance of the cells in an undifferentiated, merismastic state. Plays a role in the regulation of gibberellin 20 oxidase and the gibberellin-regulated protein GASA4. Localizes in the nucleus during the cellular differentiation state and may act via a single strand cutting domain. Transcriptional regulator required for the induction of dormancy during late seed development. Interacts genetically with FUS3 and may be component of the same regulatory pathway during embryogenesis. Binds both linear and supercoiled DNA without sequence preference.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Localizes to the cytoplasm in non-differentiating cells and to the nucleus in differentiating cells.
Domain:
Contains a bacterial GIY-YIG-like domain which can functionally replace the bacterial GIY-YIG domain in the UVRC protein.
Sequence:
MEFGDGVSFAVVPTVFKREDYKRTKHDTVFSKWQVLIGSNDWEDFKNGKDGVGRYRVQNLPRKSCPGLYELGVAVIGQEQCRKLEPDIVLASYLGQAESVRSRLQRYGRSGAHLRNVNNLNDCETIESPVKAVTGGLFEDIFSKGGSILYRWAPMGSKREAEATEGMLLSTFDYAWNKGSNGERRQLDLLKKLGDREFMSKRKSGISRMLFPFLRNQVGIRIKGEKHVLKEERKLTCDVDEEKSNNFLTSILKLTRSRPQPVSDRFDEVDGSCSDIVCGVLLEDGGCCIRSPVKGRKRCIEHKGQRVCRVSPEKQTPPKSEIFTGQDHHNHKDSDVVCGVILPDMEPCNKRPVPGRKRCEDHKGMRINAFLFLLNQTDREKTVKDEKPDPESHTESIEEEALTRFCEATTKNGLPCTRSSPKGSKRCWQHKEKTSSDTSPVYFQPEAAKNVACGVKLGNGLICERSPVKGRKRCEEHKGMRIT
The following text describes a protein:
Function:
May be involved in vacuolar sorting and osmoregulation.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Sequence:
MAGSVSRQPKAREGEVYQHSGAPSPSSQDVIESSDEVMRGSEIGLCVTKMPSRGEAAAEWLAMVVILLFGMWLIFRYQMELLPPPVSGNDAGLRGFAEERAYKHVESLSSFGPHPLRSKALGHAIQYVLDQVTEVQQTENSEVKVEVDYFHASPGVTQLTGICDGESTVYYGLKHVIARLHPKYEDSALENAILVSSHIDTVITSQGAGDCSSCVGEEEGLLGAHSFMTQHPWRETIRAAVDLEAMGVGGKHWLFQGGPDAFLVETSYAKVAKWPATIMLAQDIFYSGLVKTTTDFQIFREVGGLTGLDFAYMENSAVYLTKNDKLKLLRPGSLQHSGDNMLPFLREIATSPELASRNLTYPTGFSNMNVVYWDILGWYMVTYSQDFAKLLHHSIIFQLIVLQVGDIYLSGIPCLVASCLAFLTICFTWCFALGFTLLVAILVPTLGSSAVPFLACPWLAIPLYCLPAAIGALVGHRFGHMLLVWYLRHVDEEQHKKTQSTLEQVVPEKNLAINAPYTVLCEAQRWLFKAGIMQRVLVLVLATWAKAGSSYLALAWVVALRKLRYLTFRLGVVAPAALTALSAFQLPLVFINMVVNFDRDPGDLPVWVGSVMIACICAAITTLMLVCLLPYVHRSGRLAYVLGVLGAILLLALASVAISIFPAFTPDVGRGINVVHVIDADGQNSGRNSTNSFLSLASVTMGSLDPEAKHMGDADLVCNRNNTIDFVTHKVKYGCQKPILLDESLWEDRPSLVVIKDEDGPPRVTTVRLSAGKACRWFLTVNSNKVAKFQLEVTIDSKSPQQVLVPTTKTSGVVGWHLIQYNGDPAGPSNFLLILHWFQNATDFDASKLLKLRTDVDLTTPEAAKMLDELPKWCFGFGMPSSPYLLAYLASM
The following text describes a protein:
Function:
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
Sequence:
RSHAGGGRRRANVVRALRAPQPELARAPRRAAEPARGCPDVRRSRKPRPAAGPARAPPPSAPRAAALRFLLLLPPSPFSCLEVAGQRKPLQRVRHGSGASARLQPPSRLAPVPPLPLLSASPPSRRLSSRSLCLRISTLISLLPRPPPRAQSPGRRGPRGAAAPPPARTPSPAGVPRAAAAPAERSWAAAAASCGSPSERRHSPLPERAVTAEQNVDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
The following text describes a protein:
Function:
Protein of the nuclear speckles that regulates RNA exosomal degradation (By similarity). Involved in short interfering RNAs-mediated silencing in nuclei. Functions with nrde-3 in the nuclear RNA-mediated gene silencing (RNAi) pathway to regulate gene expression via inhibition of RNA polymerases I and II during the elongation phase of transcription. Required for exogenous RNAi-induced H3K27 methylation.
Subcellular Localization:
Nucleus. Nucleus speckle. Nucleus, nucleolus. Note=Accumulation of siRNAs promotes translocation of the protein to the nucleolus.
Sequence:
MFRAYGNNGLKNPERISGENPDLYTQTRAAVQQRATTTLKRNEKQKLAVQNDSVFQQVGIGESDSDDDNGGVRIRMSPHRYIDPDDVFTLPEVKKQNALRDAKIAARAAQATAYNTFPSVKSLNGCQDPPETSQQSTSRKRSASNSRSPSRSHSRRYDRDNGRQRSRSREKKRRKKERRRKRSSSRSSSSSRSRDRSSRARDTSSHTLMKMNKPAKYAFLTDEEYRTCDAYISSAFITQTKSDCENYTQGVPKKEIAKCRLSVKFIVGLEHNNILFNNIYGAEYARDKENRPFWEQLDRYLKDVPKETFFRYVPPVGGYWKIRDRVDLLNLDHIDDDVLANDSDNRKDAFTFELEQAKKTFSENVHNIDALIKVISMEEEMCRRNVGSFSSSNPAALAERHQEMVKKAIKADGRNAKLRLMKIELLIKMDPNSPTIIDDFKNLTITFPHEPMVWIKYLDYIQYDSNVYNYKKLKNAFEDCIRQVTGLTNGTLLSHLNAVNDRPLLRMFHLWIYIRYLKWMISCAHTPVVLANIQATFEYNFGLADVEKRTSTNSKEREVRLEEFWESGLPRIGDEGAVGAEKMLKQSEELSDEDIQKLENDDFDILISRTEETIATCLQAQRDVQISWIEVEREMMNIDARVKRTKLKDCELYEDHVDDLETCELWDIIPFDRIRYYEAPGDCANFDFVQPFLELLGVKFLNSTNCFTTTEQIISDWISNDSTVNFYKTPTYTEKKCFEVGNNILKFMLYNRLKLTENNPEYLDKTMVKYLLAMLVTEASEQEKKLNFHSFKLNLKNLVGTFITKHPDIFKRAMLSKITGIVYMEKFVSWWERALKEQEKVVEADERRKNYKEIKMEEGVVDDVKFDVILLKKDKERVQTIRDKIRDMIDIAIPKSTEKLIQSADSSLPTLQLHLYANVLRGRLSILNQNALEETRDVFCKEILGIHTSEFESDEALLLALDQGLNELLEHCKEKDNLESVDSIPELPRAEALCEALKVVAVFVFLDKMAFSRRAVDCLIANAITKFEQFEAKKNDFNRGTYEKYCDQIDLKFITDTLITFFSHKKHRFIYNENFKKLIFQASQAFPCDSKYAKMLGELHSSGRLQVMKLQGFTDSRNSILNAKRDQQFDPELETRLLMNSLTIMFSWMNAANRIGDAGNQILYKNWKREAANTRDPAIWRQVIRVASKLSQKILKDDAYTRARGQCTWALNLHFDYIEAKTVRKNGDLMEMIYLILEQSMGQEHSLFVTDEEYMKTQQEIGLQYSESGR
The following text describes a protein:
Function:
Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids (By similarity). However, in view of the small size of the putative binding pocket, it has been proposed that it may act rather as an amidase or a peptidase.
Subcellular Localization:
Lysosome.
Sequence:
MSRHSQDERLGLPQPPALLPLLLLLLAVAVPLSQAGVYYATAYWMPTEKTIQVKNVLDRKGDAYGFYNNSVKTTGWGILEIKAGYGSQSLSNEIIMFAAGFLEGYLTAPHMDDHFTNLYPQLIKKRSMLNKVQDFLTKQDQWTRENIKYYKSDPFWRHADYVMAQMDGLFAGATKRAVLEGKKPMTLFQIQFLNAIGDLLDLIPSLSPTKNSSLKFFKRWDMGHCSALIKVLPGFENIFFAHSSWYTYAAMLRIYKHWDFNIVDKDTSSSRLSFSSYPGFLESLDDFYLLSSGLVLLQTTNSVYNKTLLQHVVPQSLLAWQRVRVASMMANNGKQWAEVFSKYNSGTYNNQYMVLDLKKVNLNHSLDEGTLYIVEQIPTYVEYSEQTAVLRRGYWPSYNIPFHEKVYNWSGYPILVKKLGLDYSYDLASRAKIFRRDQGKVTDMESMKYIMRYNNYKQDPYSKGDPCNTVCCREDLNSHSPSPGGCYDTKVADIYLASKYKAYAISGPTVQGGLPVFHWSRFNKTLHEGMPEAYNFDFITMKPIL
The following text describes a protein:
Function:
Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae.
Subcellular Localization:
Fimbrium.
Sequence:
MKWCKRGYVLAAILALASATIQAADVTITVNGKVVAKPCTVSTTNATVDLGDLYSFSLMSAGAASAWHDVALELTNCPVGTSRVTASFSGAADSTGYYKNQGTAQNIQLELQDDSGNTLNTGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQAVISITYTYS
The following text describes a protein:
Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Sequence:
MDIGTQTSPTPRICIAGLVGQSATGKSTLLETLLGNEPYGRMEPTLRLKCAYAKIYNCSSSHAECYRSCSRIVDIAEHQCDTPGHELNPVSVQKHVSFVDCPGNMLYVSTMLAGIMMTDGVLVLSKPSVDFYLAPTCAVLAAASIMGKSIVVLQNCTEEESANKTKIKESLRQIQQFTRLIVSIEVPIVRLSVRDKTSSKIAELCSRINNMSTPEQDVTSPALMIIANSTCDPEGSENSDETLLVTIHGRVMQGVISPNQETEVRPGIVKVGEDGKAVSCPIILKVVAIMEDAAVSGQVVALRAAANIRNDDQLKSVIKGGLGGHVLGQVGSLPAVYSALKVKFSLVRKMFNPYSEELEKVEAIEKDQDLLLTIGAMSTHGKVHSITEDMMVVSALTPPSCARKEERIFISRKQELAWNLIGHGEIIGGKSVAVVERSFPAD
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MECNQPHVPKKSSSFSSSRDEKHREINRNLSLGSIKLEQSYEKKERHDQETIEEDREEEKATKEQEEEKEASNDEEPEATLLTISEDIDRFLRLLLAVEDGQDGSHEPPEIPESTVEKFVILVEEEIAKYETGEEKWPSCDDELSLLDAIDRVSKLTSAVAKFSSELKYNEAMNHSGSVLHHAMCFLEDEFHSLLQDSRTKQEAASSSSRTKQLPSLIYRFHEPERSVSPSSESSPCESSQAYIPENTERLHRIADAMISAGYVTECCQVFSIARRNAFEAGLPSLGFEKVGIEDVIKMAWENLESEIATWVKAFRHTITASFTAERELCEAVFASHRAISDRLFLGFANGAIVQLLTFAEAVTMTKRSAEKLFKVLDVYEAMRDVLPTVEALLPDDGEQDEPSVFADPKTEISSLRYRLGEAAVAIFCDLESSIKADNSKTPVPGGAVHPLTRYVMNYLKYACEYKSTLEQVFKEHKHAEKPSSFDEDRENSQTSGGGDGDRNSNSSGNDNYNPFAAQLIEVMDLLHSNLESKSKLYKDLALSNIFLMNNGRYIAKKVKGSQTEKYIKFGPEDLENLIDELFDGTPSSSIASRRRT
The following text describes a protein:
Function:
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MDILETSFRLEDVLSSYYRVEKVVRVNYQQFVPRTPDDQWCIQSELLIRKKDPKALVALFSRELWCFSINDQDLPMPGLEGIGEPPNSEKKGHFTPGFSKPNLPTPYAIFLKALRRMIHINMCLRSQNRLVPFGNTCIFQRDEKASSVIHFDSHLFENGDLTVSLCTKDMGFERLLSGAFTGRQVKRALYLAPSGIRAYLPFPDISKCLVAPPKNAHLLLVTLLVSHGIDLTQAKDLKWIKLVPNINHLNGYTPTISRYAEESQTSKSVIWPMDLCFQQTPADACVNTTRATPLDIGLQDSFDLIEDFIQLKLTSAYRIPGTSVNANTATGNNPLSTGGGFTDQFQPFVKHTNSSSCNYGPASRTKLTPSKAQDLRRSAAPLSADSFGNGFMTTPNVNENMGSVIDDMVICPSSVKSQNDLWNDRKSSNDDIDSINPTSQQGDSARITSGSEEQDVEVTFDKDLFGDEDDESDLFGDSSNKSTHRKEVREITDEMFDSAEIESDPEGKITPTGTSINYSTQQQTPLKRKYLDIPLDEITLPAAPLYTDPGAPLPVETPRDRRKSVFAPLNFNPMIESNVDNKYKNGGKFSFDPNEIDEPLKFEVSTTNISSSEEDDSEFSGDDFDELQQNNLQDIRAMEVGSSLQQYDMGRPINEFLNQSDSAKEDYLLPAYQSGDVIDVDKFPSRESHLDQIWKSPEINREDTPHRIGLPIIKPQLDGSGNLDIDNQITDNCSSNYYEPTPVVGADEKIQERTLHKDKKLDQQGDSAMASVVGDYSLAIKETRESSNGLPFLLRHMPLFSIPDVFLSKNPIVKVDSKLEDFLEILCEQLVFDQGFLGNFDVDPPTYKDVKLNEKGVIRETLNSVFSEFERLRGNEIISDMFYIKQPSVCVKKHGNLIKLKSDAESFAPLLHLKPSRGMKSFRGLFLTTILTQTCVSFITELAHIYSAQELGFCELVKLTNDEHNGLIVLNNFNTDTLLLLSAQIVSYCSTNMNNVKNIPLMIFLPVAPSSLEATITMTSKFQLIKNEVKSRLPDVELLLKLIPFDLTKDPVIMIDRYYELCRGIYNLLPPRTVKFASIADNLPEQVEFRTSAGNQNQLSHYDSYIHLAYTRSIDREWLAAAWSDSKGTENMVKAWYLGNSKARFETACNELWKLTVELASRKYGRICLILTRMDSVLPDDELMHWRRLSVTTRNLHLAVVCVGASTKVSLYDEDQFYPSFKPLFKDKRYANKIQANQLDDYEVVNIDEELHGVVFSSPLQLANSQHRCAIKSGALVRFKRCAGGDTLDKFEVNLLNCPHSDSTKLLKTILHQFRDIASLNTWFCISRGKDNYIPWHVVAVKKIMRFIIHVNGIEEK
The following text describes a protein:
Function:
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
Subcellular Localization:
Mitochondrion.
Sequence:
MISNTFKIRCPLPLKRISSTSIRTYRVMAIESSCDDSCVALLEKSHPKTPPKIIDQFKRTLHSADIGGILPTAAYNYHMATIANMVQEFCHKHQISALNPPDLLCVTRGPGMAGSLSTSTEFAKGLSVAWDVPLVGVHHMLGHLLTANLPNSEQPKLPPPNYPFLSLLCSGGHTMLVLSKSLTEHEIIVNVGDIAVGDSLDKCARELGMYGNMLGKELEKYINSIPEETRNQYEKLSVNTRIANPYNFRLTLPYSAPKYGIPGDVKFAFSHFLSNIQEYKAMHYNKNRGEGESEGEGEIDLTLDEETKQFIAYKTQEFIFDHIVDRINIAFKKHGIKNRNSDGTFIGVKDFICSGGVAANNRLRQKLREKLDFQEIGTDNVNVNFHFPDLSLCTDNAIMIGAAGIEIFEKLRLRTDLSFLPIRKWPLNKLLDVDGWVKVEEEEFNRICKY
The following text describes a protein:
Function:
Non-heme iron oxygenase involved in sterols biosynthesis by catalyzing the removal of the second methyl group at the C-4 position. 24-ethylidenelophenol and 24-ethyllophenol are the preferred substrates. Together with SMO2-1, required during embryogenesis, probably by maintaining sterols and auxin homeostasis.
Miscellaneous:
MISCELLANEOUS: Requires a membrane-bound cytochrome b5 as an obligatory electron carrier from NAD(P)H to SMO.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
The histidine box domains may contain the active site and/or be involved in metal ion binding.
Sequence:
MASFVESGWQYLVTHFSDFQLACIGSFLLHESVFFLSGLPFIFLERQGFLSKYKIQTKNNTPAAQGKCITRLLLYHFSVNLPLMLASYPVFRAMGMRSSFPLPSWKEVSAQILFYFIIEDFVFYWGHRILHSKWLYKNVHSVHHEYATPFGLTSEYAHPAEILFLGFATIVGPALTGPHLITLWLWMVLRVLETVEAHCGYHFPWSLSNFLPLYGGADFHDYHHRLLYTKSGNYSSTFVYMDWIFGTDKGYRRLKTLKENGDMKQT
The following text describes a protein:
Function:
Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHSSVPPVLYRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD
The following text describes a protein:
Function:
Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
Subcellular Localization:
Endomembrane system; Peripheral membrane protein. Membrane, coated pit.
Sequence:
MEGAKTYIRGLQNFTESIHKCTSLEKEKELVNCELAKIRKEFKEGKISSYDRRKCVLKMAYIEVLGYEVDTGFVEVIQLLGSSKYFDKHVGYLAFVLLFSNVPESSRMIINTLQQDLENNLEPVLCDALTVISTLANMEMADTLAPSVLKLCTGFCETNVKKRALITLRQLYKFQPNVLSINPDFMKALEKLLSTEMDLGIINAMVLLLIEIGKKQPELLKPFGTELTNILQRLVNHEYTPEIDYHETSAPWLQILLFRLLSTIDLETTTQKIFWDSARKVLGTSDTLRFDKPCNEKTIQMSIIFEVMSIVIKHEKEEYFEILLPLLGTLVEDKEVNIRYLALDTFVLLGQANYKNVCQNYLVHILNSLDEPDVTIRRRAVDVLYALCTPQSVRKVVNQLLHVLENDEGELKEELVVKISILAEMDPVRDQWYVDTMLLATCLGGEFVRPELWDRVLSSLGNAAQYAVQKIVQVLHGGCWHEEFLRMSCVILGEYPQLLGALAMKVASYITKQLPYVSSTSKRLILTCLIKMAKELNEVRPVCQKACHMYLSAVDVEVQQRAAEYLNIMNKNAYEIAIAPLPERAINENKESQENEKTNKDDDQFMSQQVSEPHTNVNNSSHINESIPTQTSTQTNVLDLFGSIPSQQITENQPKQLPLDHTPYTERGYKGSVFTHSHADAELGKKVRFIHKKLLLQKEGVLFQDSCIQIGMRMKCSNTVDVALYIGNTQNQNINLQIALKGEEGINCLLQTNQVSIEPKKQQQVLCRFELKQLFLQAPMVGLAYTIGEQNIQLSFSLPINILRYVQPLNQSVEFLNQKELLGDCLLQSQIQSSMQLKDLQQLFELNNFKIISSSSNQLVCGGIILDQPIGIFVDVLGGSYNIGVGSYKLAIAQVVNDCIGYLLSNTF