lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices HAC1 precursor mRNA to produce the mature form which then induces transcription of UPR target genes.
Miscellaneous:
MISCELLANEOUS: Present with 259 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MRLLRRNMLVLTLLVCVFSSIISCSIPLSSRTSRRQIVEDEVASTKKLNFNYGVDKNINSPIPAPRTTEGLPNMKLSSYPTPNLLNTADNRRANKKGRRAANSISVPYLENRSLNELSLSDILIAADVEGGLHAVDRRNGHIIWSIEPENFQPLIEIQEPSRLETYETLIIEPFGDGNIYYFNAHQGLQKLPLSIRQLVSTSPLHLKTNIVVNDSGKIVEDEKVYTGSMRTIMYTINMLNGEIISAFGPGSKNGYFGSQSVDCSPEEKIKLQECENMIVIGKTIFELGIHSYDGASYNVTYSTWQQNVLDVPLALQNTFSKDGMCIAPFRDKSLLASDLDFRIARWVSPTFPGIIVGLFDVFNDLRTNENILVPHPFNPGDHESISSNKVYLDQTSNLSWFALSSQNFPSLVESAPISRYASSDRWRVSSIFEDETLFKNAIMGVHQIYNNEYDHLYENYEKTNSLDTTHKYPPLMIDSSVDTTDLHQNNEMNSLKEYMSPEDLEAYRKKIHEQISRELDEKNQNSLLLKFGSLVYRIIETGVFLLLFLIFCAILQRFKILPPLYVLLSKIGFMPEKEIPIVESKSLNCPSSSENVTKPFDMKSGKQVVFEGAVNDGSLKSEKDNDDADEDDEKSLDLTTEKKKRKRGSRGGKKGRKSRIANIPNFEQSLKNLVVSEKILGYGSSGTVVFQGSFQGRPVAVKRMLIDFCDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALELCNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPELLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGDKYSRESNIIRGIFSLDEMKCLHDRSLIAEATDLISQMIDHDPLKRPTAMKVLRHPLFWPKSKKLEFLLKVSDRLEIENRDPPSALLMKFDAGSDFVIPSGDWTVKFDKTFMDNLERYRKYHSSKLMDLLRALRNKYHHFMDLPEDIAELMGPVPDGFYDYFTKRFPNLLIGVYMIVKENLSDDQILREFLYS
The following text describes a protein:
Function:
Is involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MANEEVILLDFWPSMYGMRVRVALAEKCVNFEYKEQNMVEKSSILLEMNPIYKKIPVLIHNGKPICESLNVVQYIDEVWKDKVTFLPSDPYEKHQAMFWADYVEKVFDTGRKLWMEKGGEKQTRKENYIDTLRMLEGILGDKLYFGGEKFGYLDISLIGICSWFYTYEKFGEFSTEVETPKIIAWMKRCMKRESVSKYVVEPLKVYDFALQIRKHYGIE
The following text describes a protein:
Function:
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.
Sequence:
MEIAGPGGSGAGWWGACTLAVVVLCLLSLPLGTEVAGTTTQRSTQPSEEIQPQADTQAECGIPAVTGKIFGGRDAPQKRWPWQASVLYRGMHICGATIVSAYWVISAAHCFQKSHHPDDYQILLGYYRLKSPTQHSLQMSVYRVFVHNDFNKRYFMGSDITLLQLYGPVNFTEYIRPACLPGRNPQVSSSASCWITGWGMVTETTMLGDPYTLQEAQLGIMDSQICTMFFQGPQPGNNTYSVQDDMLCAGDLMTGKSICRGDSGGPFVCNLNNVWFLIGLSSWSLPCQQPVSPSVFTRVSYFSEWITQKQNSSPNPDPSSVPHPPSVPPGVPIFPSLGNIHKPRSVLTLVISQVLVLLLISLWTLQL
The following text describes a protein:
Function:
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MDLKHMNLLPYQITCFYGCVLLLLLLLTLAPAQNTTSSTSIKAANTTKPGCRKRCGNVTVPYPFGIGSDCAINSGFEVICNVSTDGTQKPLIGSIEVYDISDAELRVKNAIAWRCYNENGSMYSENLNWMYLGGSIYPYSFSARNMFILVGCDDNALITGPNFGYNCSTSCTSSNDVIEGKCMGNGCYQVHLPRGFKNFTPTISSTRNHTDVWDFNQCGSAFLGEVDRFHFRGLEDVSNVTTFYKSIMASVPIVLDWAIGDFTCTQAQDGKDYACKENSECVDSDAGFGGYRCSCKPGFQGNPYLTAGCQDVDECSDPSANTCEKNCTNTPGSFYCSCPDGYTDDGKKDGRSCIPPYTDHQSLWTKFSLGTGVGSISLVVVITLLYFCIKKRKLIQAREKFFQQNGGLLLKERIATKEGAVEATRIFTAEELKKATNNYANDRILGHGGNGIVYRGVLRDTRIVAIKKSRTVDESQIEQFINEVLILTQINHRNVVKLFGCCLEDEVPLLVYEYVSEGNLYEHIHNQRGVGWLTWQNRLRIAAEIATTLAYLHSFASMPIIHRDVKSANILLDNVYTAKVADFGASRLIPLDQTHVATLVQGTSGYLDPEYFRTSQLTDKSDVYSFGVVLAELLTGLKPIIRARSEENKNLADFFVLSMNSNSLFHIIDHRVLREGSLEQLQKMAELVKNCLQPHGEDRPTMKDVSIELEEELKKATNNYANDRILGHGGNGIVYRGVLRDTRIVAIKKSRTVDESQIEQFINEVLILTQINHRNVVKLFGCCLEDEVPLLVYEYVSEGNLYEHIHNQRGVGWLTWQNRLRIAAEIATTLAYLHSFASMPIIHRDVKSANILLDNVYTAKVADFGASRLIPLDQTHVATLVQGTSGYLDPEYFRTSQLTDKSDVYSFGVVLAELLTGLKPIIRARSEENKNLADFFVLSMNSNSLFHIIDHRVLREGSLEQLQKMAELVKNCLQPHGEDRPTMKDVSIELEGLRKVTGISSSSQHEQEEYDQDEISDLYTVPINSYENTPNSDSSRIMHPTYSPS
The following text describes a protein:
Function:
Involved in sperm flagellum assembly.
Sequence:
MATANTALTGGRCCAATLAAAMIPPADSLLKYDTPVLVSRNTEKRSPKARLLKVSPQQPGPSGPVPQPPKTKLPSTSCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK
The following text describes a protein:
Function:
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAFGQRNTSRGGRGGGGSSFRGRGGSRGGPRGRGGLRGGRGRGRGRPVFDSARLAQQKEEGEESNSESEESSQDEAMESEEESSDDDDAEPAPAVKSYAALMQSFTADSAPQAKRRKLNVDKEEKQDEEADLMDQDANDADHVEEAEEGPETATDGLLEEEDEEDNSDPFEAHFANPDDNILSRRLKHLENGQWAIQKSILAKIGRAITSVPGDDEAKQTKSSIINSPEELKLKQKLAGVMKKQCPTFDTLEKSISPLIFGYQDLLFCERNTSNAESLRRLTCLHAVNHVFKTRDRVIKNNSRLAREDNSDDLELRDQGFTRPKVLMLLPTRESCVRMVDMITSLCEPDQQENRKRFNDSYVDKEEKYSTDKPEDFRELFAGNDDDMFRLGLKFTRKTVKYFSQFYNSDIIFASPLGLRMAIGNEDAKKVDHDFLSSIEMVIVDQADALLMQNWEHVEFIFDHLNLQPKEAHGCDFSRVRSWYLDNNAKYFRQTIALAGFNTPELNTMFYNQSKNWAGKVKVSSNYPGAIQELGLKVKQTFSRLDSQSFASDPDSRFEYFTSAIIPTLTRRSKDSAGTLLFIPSYLDFVRVRNYFSTSATTRTLSFGSISEYTTPKEVARARSHFYSGRHTILLYTERAHHFRRYQIRGVKKVIMYGLPDNPIFYKEIVGGYLSRSVREGDLEPGDGSVRVVFSKWDVMKLERIAGTERVGKMIKEKGDTFDFL
The following text describes a protein:
Function:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Essential arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins SmD1 and SmD3.
Sequence:
MTNNAILVQKFNPGTGNLEWDLQAEDYDYTQEIARAGFADMLHDEERNLKYNLALQKALNLLKSKGKEAFVLDIGTGTGLLAMMAVKGKASSVTACETFQPMVKCSSEVIAHNGFRDSINIIPKRSTDITVGPNKDMEQRANVLITEVFDTELIGEGAIGTFNHANQHLLTEDSIVIPARATIYVQLIESELVSSWNRSKPIQLNGQIIQPPADVANCPGNGAVHDIQLAQLTPEHFKALSDPIPIFNKEPIPNDDSKTVQFTAKSSGTAHAVLMWWTLDMDTEGEIVLSCAPPWAHPEGNELPWRDHWMQAIYYFPNDKTIKSEGEQLRLSGYHDEYSLWFGLQTEASSSAILPRPFCDCSVHLAVSRPRLGQLNDSERNQKYQTALEKVVSSDTVCLTLGDCCLLGLIVAKLGAKKVYAVERNPHCRRVLQAWVKRNDLQEQITVMDGDLDKRKLDLKVNLVLGEPVFESSVLPWHNLYFARWKNNVQHLLADGVTRIFPGKAYLYAMAVEMKDLWKIRAPVRSTQEIDLSVFDKLIESAIDSSDAQVEPHPLWEYPTRALSQAVQLMMLDLTTLSGKTQEILQVEGKVNLPVAGTLNGVALWIDWQLDENTRISGGPTAPVTLSQNVQWDVHSKQAVYFTKDPVSISNVSFLVKQDATAAEAKHRPASGQLQLVDSSRHE
The following text describes a protein:
Function:
MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSKVSGANETLQGALAPLSHMGGGGDATLLKDEGQVELPRGPGVLNVQVLPEEGHAHLQDLEGYKSMDPRQSESASTDVSEMLQHTASLDDPIQFTRVSTSSVTSNSSSDPRESGDTQETGSRRGCSTEEQAPAGAERVSGQDQDSWDVEEVVAEPRSGIDVTPVGDVTNSTIRASGRSAESTSHYLDEYSDTRYSSSSPSSGSRKLSTTIITPEKNVVAQALHCYADNYESPLNDLMSSGDERSSSVRETSFENASSDTNANLNGGRASTGESMRSPPPATGLPNGFVHTQASAPALPVLPAKSPFRAVQSPFSGTRKSRNSANLAELSLPRTSTSSASSMEQRKSRGGRMKVVLSSFVQNIRRNSQGEKRRSGTAMKISTPYNATHVHHVGVDSRTGEYTGLPEEWERLLASSGISKKEQQQHPQAVMDIVKFYQDVTGTSGEDKVFKTFNVSSTNACELSSSPSFKTPSLSSITRFEGSHEAYNSAYHSPMLQSPMGFHDPQHDEKFIPSRPAPRPPGGAAPKTDFTSPLAYDSQSATATPKNQRFSNQSSGFFSLARKATLNKNKQQLPPIPSAAAASAPITQPGSTANIPYIKPAENPVSAPSKSIPPSLPAVPTPPPPIEKDPPLRDLEREREREHSSAKQGQLALERKREEKRRRNQKLQAKLAEICSPGDPSKIYRNLVKIGQGASGGVYTAYEIGTNASVAIKQMNLEKQPKKELIINEILVMKGSRHNNIVNFIDSYLLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIAAVSRETLRGLHFLHSKGVIHRDIKSDNILLSMDGNIKLTDFGFCAQINETNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKDADSLSPVLKRFLSWCLQVSPNDRATAMELLYDKFIVEVAEANASLAPLVKLARMKKLAEKMDADSDDNRTD
The following text describes a protein:
Function:
Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
Subcellular Localization:
Virion. Host nucleus.
Sequence:
MKTNPLPATPSVWGGSTVELPPTTRDTAGQGLLRRVLRPPISRRDGPGLPRGSGPRRAASTLWLLGLDGTDAPPGALTPNDDTEQALDKILRGTMRGGAALIGSPRHHLTRQVILTDLCQPNADRAGTLLLALRHPADLPHLAHQRAPPGRQTERLGEAWGQLMEATALGSGRAESGCTRAGLVSFNFLVAACAASYDARDAADAVRAHVTANYRGTRVGARLDRFSECLRAMVHTHVFPHEVMRFFGGLVSWVTQDELASVTAVCAGPQEAAHTGHPGRPRSAVILPACAFVDLDAELGLGGPGAAFLYLVFTYRQRRDQELCCVYVIKSQLPPRGLEPALERLFGRLRITNTIHGTEDMTPPAPNRNPDFPLAGLAANPQTPRCSAGQVTNPQFADRLYRWQPDLRGRPTARTCTYAAFAELGMMPEDSPRCLHRTERFGAVSVPVVILEGVVWRPGEWRACA
The following text describes a protein:
Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Sequence:
MAVTSEGVGGAGLKRVHLGIPEAVFVEDVDAFMKKPGNETADAVLKKLDEQYQKYKFMELNLTQKKRRLKNQIPEIKQTLEILKHMQKKKGTTEPMKTRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDINEAQALLEKNLSTASRNLGSTEEDLDFLRDQFTTSEVNMARVYNWDVKRRNKDDPSKSKA
The following text describes a protein:
Function:
Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The JAMM motif is essential for the protease activity of the CSN complex resulting in deneddylation of cullins. It constitutes the catalytic center of the complex (By similarity).
Sequence:
MNNQLENVFRFDEEKERAKIRESPWKHDPEFFRSVKISAVALLKMLRHVSQGMPLEVMGYVQGKVEGASLIILDSFALPVEGTETRVNAHEEAQEYSVQYHTLCKSVYRHENVIGWYHSHPNYGCWLSGVDVETQRQNQKYQDPFVAVVLDPKRSLESPYVNIGAFRTYPVGNDGSIRTKSRHHPSVLFKNLPSSKIEDAGAHAEAYYSLPITYFHSKAEKKVTEFLRNRNWSRSITECSILQNNEFLHDSEKLIDHLIHETGNNELPVASAYEQSKACCNELSTFLSQIDVQDKLFKE
The following text describes a protein:
Function:
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
Subcellular Localization:
Chromosome, telomere. Cytoplasm, cytoskeleton, spindle. Nucleus.
Sequence:
MEERESRSEVSAEFSEVEHVAKSWMLDFVIGSLCHHFRHDKYKEFNQSLSVLEALIPGFGQFKSYQKKMINICFVLSRIVNGKKTSLQYEEDARITPLMSASHIWNVIEQEIEQKTLYEDIKRLLFVQSVAVCLQSGQHQKASWVLERLTETTEVPQNLRMKLSMIVNKKDAYHQFLLNFSFDVLLEKIKILLDSFQKDYLSDFLLKAASKVVEASKEKGVEEETTEIQESGTAAPNEAQLQSDGPFQQEGVDAGPKITDVNYSNGNVFSLTPSASLLAKKTFRPRRKLFSVQNIEHWKPKSSRKSFLVCRRNYSIRGTRLSFDFTKRKTSELKKKRVKRHWTFEENQALKAGVRRYGEGNWAKILKHFEFNNRTGVMLKDRWRTMKKLYLVSENNSSED
The following text describes a protein:
Function:
May be involved in the regulation of photosystem II.
Subcellular Localization:
Plastid, chloroplast thylakoid.
Sequence:
MADEEEQGVSRRLALALAAGALVATGKVSTASAAYGEAANVFGSPKQQSGFTTLTGDGFKLDVPSKWNPSKELEFPGTLLRYEDNFDQKSNLAVMVIPTDKKSITDYGSPEDFLSAYSYLLGKQAYAGKTVSEGGFDPNAVATAAVLQSKTKDINGKKYYDLDVLTRTADGDEGGTHQLIVASINNGKLYLLKAQAGDKRWFKGAQKFVKGVAESFSLA
The following text describes a protein:
Function:
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Subcellular Localization:
Cytoplasm.
Sequence:
MSLVSGARDMGFDDNNNNKNNKDGDDENSSSRTRADDDALSRQMSESSLCATEEEEDDDSKLQLGPQYTIKEHLEKDKDDESLRKWKEQLLGSVDVTNIGETLDPEVRIDSLAIISPGRPDIVLLVPENGNPKGMWFTLKEGSKYNLKFTFHVNNNIVSGLRYTNTVWKTGVKVDRAKEMLGTFSPQLEPYNHVMPEETTPSGMFARGSYSARTKFLDDDNKCYLEINYSFDIRKEWPAL
The following text describes a protein:
Function:
Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity); Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Regulates the centrosomal levels of kinase aurK/Aurora during mitotic progression by promoting aurK removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis.
Subcellular Localization:
Nucleus. Golgi apparatus, Golgi stack. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MSDHSEAIATFQSITGASKEESTFYLESHDWDLEKAAQTFTTLQEEENQRNDQPQIEEDYEDEEEEDDHRDPMPASRPVYSKPVAKTVSKKAPAGGRVGGIRTLSDFNNDDHDDHDHSDGDDDEDDRSQQYFTGGEKSGLVVESAPKKGKNGGSGDIVNDVFDSAKRHGAVASNEKKVEKPDSFDSVGYQLGATDQGNRNVSKPKEKDPNSQVVEVKVTFWNQGFTIDDGPLRKYDNPENKELLDDIQRGIVPRELQKKATTPNGLSVTLINNHNQDYVEPAKPKYVAFSGGGQTLGSSSTSTNNNNNNNNNNNNRATTTSTTTTSTPNVSSINVDQSQPTTTVQIRLANGSRLSTTFNHSHTLQDVINYINSSSGSNQSFDLLTGFPQKPVTNPTSTTLKDAGLLNALLIQKLK
The following text describes a protein:
Function:
A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGGLAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFLPLIVTWVLVLVVQILAPAVINNKG
The following text describes a protein:
Function:
Responsible for addition of the terminal mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose. Implicated in late Golgi modifications.
Miscellaneous:
MISCELLANEOUS: Present with 1780 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MLALRRFILNQRSLRSCTIPILVGALIIILVLFQLVTHRNDALIRSSNVNSTNKKTLKDADPKVLIEAFGSPEVDPVDTIPVSPLELVPFYDQSIDTKRSSSWLINKKGYYKHFNELSLTDRCKFYFRTLYTLDDEWTNSVKKLEYSINDNEGVDEGKDANGNPMDEKSERLYRRKYDMFQAFERIRAYDRCFMQANPVNIQEIFPKSDKMSKERVQSKLIKTLNATFPNYDPDNFKKYDQFEFEHKMFPFINNFTTETFHEMVPKITSPFGKVLEQGFLPKFDHKTGKVQEYFKYEYDPSKTFWANWRDMSAKVAGRGIVLSLGSNQFPLAVKFIASLRFEGNTLPIQVVYRGDELSQELVDKLIYAARSPDFKPVENNYDNSTNVPQEIWFLDVSNTIHPKWRGDFGSYKSKWLVVLLNLLQEFVFLDIDAISYEKIDNYFKTTEYQKTGTVFYRERALRENVNERCIARYETLLPRNLESKNFQNSLLIDPDHALNECDNTLTTEEYIFKAFFHHRRQHQLEAGLFAVDKSKHTIPLVLAAMIHLAKNTAHCTHGDKENFWLGFLAAGHTYALQGVYSGAIGDYVKKTDLNGKRQEAAVEICSGQIAHMSTDKKTLLWVNGGGTFCKHDNAAKDDWKKDGDFKKFKDQFKTFEEMEKYYYITPISSKYVILPDPKSDDWHRASAGACGGYIWCATHKTLLKPYSYNHRTTHGELITLDEEQRLHIDAVNTVWSHANKDNTRSFTEEEIKELENSRHEQS
The following text describes a protein:
Function:
Hydrolyzes phosphatidylserine as well as phosphatidylcholine.
Sequence:
MISKSRRSFIRLAAGTVGATVATSMLPSSIQAALAIPAHRRHGNLKDVEHVVILMQENRSFDHYFGTLKGVRGFGDRMAIPLPDGQRVWHQKGSKGEILPYHFDTSTTSAQRVDGTPHTWPDAQQAWNEGRMDKWLPAKTERSLGYYKEQDIAFQFAMANAFTICDAYHCSFQGGTNPNRLFLWTGTNDPLGQHGGPVTTNDHDSNGPVEQGYTWTTYPERLQAAGITWRVYQDMADNFSDNPLIGFRQYRAAAPDSPLIVNGLSTWKLDALKRDVLANSLPQVSWIVAPAKYSEHPGPSSPIWGAEYTSWVLDALTANPEVWSKTALLVMFDENDGFFDHVAPPAAPSLNKDGTLRGKTTADATLEWHTKGDIRYRNQPYGLGPRVPMYVISPWSKGGWVNSQVFDHTSVIRFLEQRFGVMEPNISPWRRAVCGDLTSAFNFANPNNEPFPELPDTSQADAIVASQIKLPKPKPPAVAAMPKQEMGIRPARALPYELGVHARYRSGGDALSLTFANTGKAGAVFQVFDLLDSENPPKRYTVGARKRLHDSFQGDASGDYHLEVHGPNGFLRVFRGNLRRDLAERKAPLPEVRIDYEPLFGNLRVQLINRGRHPVKLTVKDNVYRQGERRTVNVPPGQRREVRYSLRSSGNWYDFSVSAQGADSFLRRFSGRMEDGRSGFSDPGMGLGTLTF
The following text describes a protein:
Function:
Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions. Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
LDSHSFHQAILPPFSFCYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLRGNAYPYCRTGELCGNEYMKDDFLIKIETWHKPGDLGTQENVHKLEAASWKGVEVVYIDIADRNQVLAKDYKQEEDPAKFKSIKTGRGPLGPNWKKELPNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIQKQEKRLFTNFHRQLFCWLDKWVDLTMEDIRRMEEETKKQLDEVDQDPVLIRV
The following text describes a protein:
Function:
Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia.
Subcellular Localization:
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MGIVFSPLGLVLVFTAAITPQWREGHARLTVSGTGSFLRAGAKGQRTGGRSGSAEVLLLRSDGLWESCMQVEHSDLRQCWPVTGPYQRDPCVRLAQGLVLTSLFLCGIGIVLACIGVRCWMDLPLRGVAASGGVLVVIAGLLSLSALGVYTHNLKRLGTDPSQRISNPKLPQLSLHPAGSLYFGWLGSCLQVVGGTALLFCFKQPRCPTCPSRPEQTVCPACRSCPEITSKTDMDVYEVSC
The following text describes a protein:
Function:
Required for vacuolar ATPase assembly.
Miscellaneous:
MISCELLANEOUS: Present with 2030 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MFEIKLNDRITEFLRKFKNSAKSNEGIDEDIDLFLKRHAIPMQSLLFYVKEYRKDSDLQCSIKELLKPLEFEFKPKAVRGLHYSEDFKKKLEFLKYQEQELEYQSMVKRSKSVFSLQEDDELTPSQINKQIKEQVTTVFNVLVSVISVVVAIWYWTGSSTNFPVHVRLLLCLFFGILVLVADVVVYNSYLKKLEEAKVKEKTKVEKKKVLSKITL
The following text describes a protein:
Function:
Could act as a modulator of glutaredoxin biological activity. May play a role in cytoskeleton organization.
Subcellular Localization:
Cell projection, ruffle membrane. Cytoplasm, cytosol. Nucleus.
Sequence:
MVVKVYFTSVTGSREIKSKQSELMRILDSKCIEYERVDISVDDSVRTEMREKCGNPKAIPPQIFSNDLYCGDYEEFSAAVENDILSQFLKLKD
The following text describes a protein:
Function:
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
Sequence:
MSITNEQILDAIAEMSVMQVVELISAMEEKFGVSAAAAVVSGPAAAAAVEEQTEFNVILAAAGANKVAVIKAVRGATGLGLKEAKALVDGAPASVKEAVSKEEAEALKKELEEAGATVEVK
The following text describes a protein:
Function:
ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in early endosomal transport. During sprouting angiogenesis, in complex with PACSIN2 and MICALL1, forms recycling endosome-like tubular structure at asymmetric adherens junctions to control CDH5 trafficking.
Subcellular Localization:
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, adherens junction.
Domain:
The EH domain interacts with Asn-Pro-Phe (NPF) motifs of target proteins.
Sequence:
MFSWMGRQAGGRERSGGMDAVQTVTGGLRSLYQRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPNMFGKENKKRELIYRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMGLISQEEMNMPTQMVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLPKAD
The following text describes a protein:
Function:
Has an organic peroxide-dependent peroxidase activity.
Sequence:
MKKIGLSLCLVLSLGFLKAHEVSAEEIADIFYKLNAKEPKMKINHTKGFCAKGVFLPNAQAKKDLDVPLLNEKEIPASVRYSLGGVAMDDKSKVRGMALKLENQNASWTMVMLNTEINFAKNPNEFAQFFEMRIPKNGKVDEARIKKLYEEVPSYRNFAAYTKTIGISSSVANTPYYSVHAFRFKDKKGKLLPARWKFVPKEGIKYLNPQELKQKDSNYLLSAFQQHLKTKPIEYQMYLVFANKNDATNDTTALWKGKHKELLVGTLKVEKYEGMGCNKDVYFPADLPKGVEAPTDPLFQIRNEVYGITFSRRQ
The following text describes a protein:
Function:
May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A.
Subcellular Localization:
Cytoplasm. Synapse, synaptosome. Membrane raft. Postsynaptic density. Note=In neurons, localizes to postsynaptic lipid rafts. In myocardial and skeletal muscle cells, localizes to the cytoplasm adjacent to the inner cell membrane, polarized to one end of the myocyte (By similarity).
Sequence:
MGCGGSRADAIEPRYYESWTRETESTWLTYTDSDALPSAAATDSGPEAGGLHAGVLEDGPSSNGVLRPAAPGGIANPEKKMNCGTQCPNSQSLSSGPLTQKQNGLWTTEAKRDAKRMSAREVAISVTENIRQMDRSKRVTKNCIN
The following text describes a protein:
Function:
Participates in receptor endocytosis during interphase, is also involved in mitotic processes when endocytosis is switched off.
Sequence:
MDFDSPEEKEFPGLYASEAADAKSRKSKEESDFSEDHDHSKKDLLIGRRKDKKEKGKDRGYAALEGESSPEEELDTKSPSKSKKSKTFKFTSSKSKEKREKSRDKSEKDSKHAEEEPSVSHKVKEKERDKEKDRDEPKKKDKEEKRKEKDKKADKKDKKDKKSKQLSQQQDDVSAAEEVLALGYPVFGVSVSLATERSRCHDGVDIPLVVRDCIDFLQDHLKCEQIYKIEPIKTRLMHFKRLYNNREHDSAVDELNLPTACSLLKLFLRELPEPLLTTDLVARFEEVASHPKVTTQQAELQQLLEQLPKCNRTLLAWVLLHFDAVIQQERHNKLNAQSLAMLLSPTLQMSHRLMVALLCHCNNLFADVQLIKYVPPLTSTSPKLPDTPEDIQTELRKQDSLLSQIHSEMNAGFITKKREEQLWEVQRIITQLKRKLRTFEKKQEKTAEEVDNSSSAPPAVASEDTTDSKPAGTPAVSTNNSISQEEPKTDTLTPKDAPNDFTIDPSTGFILLPKSNPHRENLLRLQIEYDELMEWQNELKARIVAERNEVYRLKQLYEQQSINSQMASLASGSQAPPESDYERIIEHYTRENALLEHKKNMLGMELKEERRACIALQVELRLQQF
The following text describes a protein:
Function:
DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription.
Subcellular Localization:
Nucleus.
Sequence:
MNNAANTGTTNESNVSDAPRIEPLPSLNDDDIEKILQPNDIFTTDRTDASTTSSTAIEDIINPSLDPQSAASPVPSSSFFHDSRKPSTSTHLVRRGTPLGIYQTNLYGHNSRENTNPNSTLLSSKLLAHPPVPYGQNPDLLQHAVYRAQPSSGTTNAQPRQTTRRYQSHKSRPAFVNKLWSMLNDDSNTKLIQWAEDGKSFIVTNREEFVHQILPKYFKHSNFASFVRQLNMYGWHKVQDVKSGSIQSSSDDKWQFENENFIRGREDLLEKIIRQKGSSNNHNSPSGNGNPANGSNIPLDNAAGSNNSNNNISSSNSFFNNGHLLQGKTLRLMNEANLGDKNDVTAILGELEQIKYNQIAISKDLLRINKDNELLWQENMMARERHRTQQQALEKMFRFLTSIVPHLDPKMIMDGLGDPKVNNEKLNSANNIGLNRDNTGTIDELKSNDSFINDDRNSFTNATTNARNNMSPNNDDNSIDTASTNTTNRKKNIDENIKNNNDIINDIIFNTNLANNLSNYNSNNNAGSPIRPYKQRYLLKNRANSSTSSENPSLTPFDIESNNDRKISEIPFDDEEEEETDFRPFTSRDPNNQTSENTFDPNRFTMLSDDDLKKDSHTNDNKHNESDLFWDNVHRNIDEQDARLQNLENMVHILSPGYPNKSFNNKTSSTNTNSNMESAVNVNSPGFNLQDYLTGESNSPNSVHSVPSNGSGSTPLPMPNDNDTEHASTSVNQGENGSGLTPFLTVDDHTLNDNNTSEGSTRVSPDIKFSATENTKVSDNLPSFNDHSYSTQADTAPENAKKRFVEEIPEPAIVEIQDPTEYNDHRLPKRAKK
The following text describes a protein:
Function:
Involved in the negative regulation of the K(+) potassium channel AKT1 by its dephosphorylation, antagonistically to CIPK proteins (e.g. CIPK23). Functions as a positive regulator of abscisic acid-mediated cell signaling during seedling growth. Involved in the regulation of seed dormancy. Acts as a negative regulator of seed dormancy by inhibiting abscisic signaling and subsequently activating gibberellic acid signaling.
Miscellaneous:
MISCELLANEOUS: Honsu means abnormal drowsiness in Korean.
Subcellular Localization:
Cell membrane. Cytoplasm. Nucleus. Note=Probably associated to the plasma membrane when interacting with AKT1 and CIPK23 (Probable). Localizes to nucleus when interacting with PYL8/RCAR3.
Sequence:
MADICYEDETSACESRPLWSSRKWRIGVQRFRMSPSEMNPTASTTEEEDKSEGIYNKRNKQEEYDFMNCASSSPSQSSPEEESVSLEDSDVSISDGNSSVNDVAVIPSKKTVKETDLRPRYGVASVCGRRRDMEDAVALHPSFVRKQTEFSRTRWHYFGVYDGHGCSHVAARCKERLHELVQEEALSDKKEEWKKMMERSFTRMDKEVVRWGETVMSANCRCELQTPDCDAVGSTAVVSVITPEKIIVANCGDSRAVLCRNGKAVPLSTDHKPDRPDELDRIQEAGGRVIYWDGARVLGVLAMSRAIGDNYLKPYVTSEPEVTVTDRTEEDEFLILATDGLWDVVTNEAACTMVRMCLNRKSGRGRRRGETQTPGRRSEEEGKEEEEKVVGSRKNGKRGEITDKACTEASVLLTKLALAKHSSDNVSVVVIDLRRRRKRHVA