lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Transports organic cations such as tetraethylammonium (TEA). Displays a broad substrate specificity.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSFQAMETFAEISQEILMSATKPPDFDFVLEQVGNYGTYQIVFFFIICLPTSLPSAFSAFNIPFVVGNPPHTCHIPEGKEYLRPLTNDTQILSCKQYNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNGKSNVDVDELVDSMKNHQNAAEEKETKRSHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCVSAMFMPDGYPWLVASASFIGKFGVGSGFAVIYIFAGELYPTVVRAIGMGMSSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILTFFLPETLGAPLPMTIEDAENFGKKPEPDSGMFTQAAKKRESQPLLEPHTPMDRRRRSSRLMNI
The following text describes a protein:
Function:
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKRSRPPSRSRSRTRSRSLNVRALVALAVMAGAVAIALTMPVRLGLDLRGGTQIVLETKSTETTKADREATDRTVEVLRGRIDALGVAEPTIVRSGENRVVVELPGVQDPKKAADVLGRTAQLTVHSVLGAAEKPADATEGRTETAEDGERVLPDESGQSLRLKAATLTGQDVKGADARFDQQNGAGWTVTVDFKDSGSDRWAQVTGEAACNPAGDPTRRVAIVLDDKIISSPQVDPSVSCGAGITGGSTQITGSFDDAEARELALLIKGGALPVPVETIEQRTIGATLGDEAIDAGAWAAVIGTALTALFIIVVYRLMGALATVALLCYGLISYAALAAVGATLTLPGLAGFVLAIGMAVDANVLVFERAREEQAARTRPSTRSALTAGFRSAFSAIADSNITTLIAAALLFFLASGPVKGFGVTLGIGVLASMVSALVITRVLAEFAASRPAVFRRPRITGISSTGPVRDALLRRDPFLMRRPRRWLAASLIVLVVAGSGILVRGLNFGIEFTGGRLIEYSTATQVDPDRARDALADAGFPRAVVQSSGDGDLTVRTEELTDTEAATVTKAVAELGGETEKVRDELIGPSLGEELRRDALIALGLALAAQLAYLAVRFRLLFGTAAVGALAHDVVILVGVFAWLGKPIDGVFLAALLTVIGYSVNDSVVLFDRIRELLGKERKAPFDRLTNDAILQTLPRTVNTGMGAVLILASLAILADDSLTDFALALLIGVGVGTYSSVFTASPLAIELHNRDTGSRPGRRRGGRTRATGKSEKPGKQVPTSRTERQEVR
The following text describes a protein:
Function:
A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles. Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip.
Subcellular Localization:
Presynaptic cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=In non-neuronal cells, wls binds to wg in the Golgi and accompanies it to the plasma membrane where the two proteins dissociate. Wg is secreted and wls is then internalized and returns to the Golgi apparatus in a retromer-dependent manner. Wls and wg colocalize in the Golgi apparatus in wg-producing cells, and reduced expression is seen in non-producing cells. Endoplasmic reticulum expression is unchanged in wg-producing versus non-producing cells. In neuronal cells, wls is localized both pre- and postsynaptically and is transferred trans-synaptically from the pre- to the postsynaptic compartment.
Sequence:
MSGTILENLSGRKLSILVATLLLCQVLCFLLGGLYAPLPAGHVTVLGSLCREDHARQNDTSFLLYSRGAGACIPVTREEVEQDSTKMANELVHVFQMPLPRDLRDLDYSRWQQNLIGVLQVEFGYDSSSELREPPRELQLTIDMRLAYRNKGDPDNGWKLYAHGVEHRYLDCVTSHVGPTETLYSCDMIPLFELGALHHSFYLLNLRFPLDTPSQMNLQFGHMHDLTLTAIHQNGGFTQIWLLLKTMLFPFVVGIMIWFWRRVHLLQRSPALLEYMLIYLGAALTFLNLPLEYLSLVYEMPYMLLLSDIRQGIFYAMLLTFWLVFAGEHMLIQDAPNKSTIRSRYWKHLSAVVVGCISLFVFDICERGVQLRNPFYSIWTTPLGAKVAMTFIVLAGVSAAIYFLFLCYMIWKVFRNIGDKRTSLPSMSQARRLHYEVPLDQKVEDWAGIVYFYTKAFFFQLHKANESKGLIYRFKFLMLATLVCAALTVAGFIMGQMAEGQWDWNDNVAIQPTSAFLTGVYGMWNIYIFALLILYAPSHKQWPTMHHSDETTQSNENIVASAASEEIEFSHLPSDSNPSEISSLTSFTRKVAFD
The following text describes a protein:
Function:
Bifunctional enzyme involved in flavonoid metabolism.
Sequence:
MATKTVCVTGASGYIASWLVKFLLQRGYTVKATVRDPNDPKKTDHLTSLDGAKERLHLFKANLLEEGAFDAVVDGCEGVFHTASPFYHAVKDPQAELIDPALKGTLNVLGSVAKTPSIRRVVLTSSVAAVAFNGKPRAPEVVVDETWWSDPDFCRESQLWYVLSKTLAEDAAWKFVKEKAIDMVTINPAMVIGSLLQPTLNTSCAAVLQLINGAETYPNATLGWVNVKDVALAHILAFENPSANGRYLMVEAVAHYSELVKILREHYPTMKLPEKCVDDKPFPPKYQVNIERAKQLGVEFTPLAENIKETVESLKEKKFYSDA
The following text describes a protein:
Function:
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). May be involved in cytokinesis.
Subcellular Localization:
Cytoplasm, cytoskeleton, actin patch.
Sequence:
MASFNVPIIMDNGTGYSKLGYAGNDAPSYVFPTVIATRSAGASSGPAVSSKPSYMASKGSGHLSSKRATEDLDFFIGNDALKKASAGYSLDYPIRHGQIENWDHMERFWQQSLFKYLRCEPEDHYFLLTEPPLNPPENRENTAEIMFESFNCAGLYIAVQAVLALAASWTSSKVTDRSLTGTVVDSGDGVTHIIPVAEGYVIGSSIKTMPLAGRDVTYFVQSLLRDRNEPDSSLKTAERIKEECCYVCPDIVKEFSRFDREPDRYLKYASESITGHSTTIDVGFERFLAPEIFFNPEIASSDFLTPLPELVDNVVQSSPIDVRKGLYKNIVLSGGSTLFKNFGNRLQRDLKRIVDERIHRSEMLSGAKSGGVDVNVISHKRQRNAVWFGGSLLAQTPEFGSYCHTKADYEEYGASIARRYQIFGNSL
The following text describes a protein:
Function:
Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2 (By similarity). Thereby acts as an antagonist of FGF-induced retinal lens fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells (By similarity). Inhibits CBL/C-CBL-mediated EGFR ubiquitination.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell projection, ruffle membrane. Note=Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).
Domain:
The Cys-rich domain is responsible for the localization of the protein to the membrane ruffles.
Sequence:
MEARAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKPGELKPLSKEDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
The following text describes a protein:
Function:
Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MKFIDELDLELVNQTLNFETSESKISGGCDIFTTKPVASDKKLYKTIDRHLESLLQENESYNAAIQQQIELENKRRDPKQAGSDCAEPAEDSPTRNANSFWEQKRRMSVSESPRADTSPLFKSQKLNDQQLKELVSHPLEVPGCKSPSNETSARGVLRRSTSAGSFENNAGSAEQQKRRTSSIGSAANGTKSPILRRSSFNRETINIGPFGPISETASRRTFAYLIGILNASYPDHDFASLKPTDFVKSSRKQLVSKFENSIIALGKQPQEWIWETINAHMDLADCVFYQYNPQESFLDDEPGHLWSLMWFMFNKKRKRVAYFYLSAFRVKNPPSTGGSVALDEYYDSNSKPELREKRRRLTIEHETNDFEGEYDLTYTSSGDGAVEDEDEDMNDAD
The following text describes a protein:
Function:
D-mannose specific lectin.
Miscellaneous:
MISCELLANEOUS: Binds two manganese (or other transition metal) ions and two calcium ions per heterotetramer. The metal ions are essential for the saccharide-binding activity.
Sequence:
MASLQTQMISFYLIFLSILLTTIFFFKVNSTETTSFSITKFSPDQKNLIFQGDGYTTKGKLTLTKAVKSTVGRALYSTPIHIWDRDTGNVANFVTSFTFVIDAPSSYNVADEFTFFIAPVDTKPQTGGGYLGVFNSKEYDKTSQTVAVEFDTFYNAAWDPSNKERHIGIDVNSIKSVNTKSWNLQNGERANVVIAFNAATNVLTVTLTYPNSLEEENVTSYTLNEVVPLKDVVPEWVRIGFSATTGAEFAAHEVHSWSFHSELGGTSSSKQAADA
The following text describes a protein:
Function:
Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
Sequence:
MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIKGVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETPEASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTSCFERVNEFLDGQEAKYKQSKKEQE
The following text describes a protein:
Function:
Required for growth promotion and enhanced seed production mediated by the endophytic fungus Piriformospora indica.
Miscellaneous:
MISCELLANEOUS: Loss-of-function mutants do not show any induction of At5g16590, another leucine-rich repeat protein located in plasma membrane microdomains.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Extracellular side.
Sequence:
MLWQTFFSSLLLLSLLFGCNGDESLPEVTDSEEAPMDKREREALYSAIQGFVGDSWNGSALYPDPCGWTPIQGVSCDIYNDLWYVTDLSLGLIYENSLPCSSSLQIRPELFELKHLRSLSFFNCFISPMVIAKEELWTNFASNLESLEFRSNPGLIGELPETIGNLTKLKSLVVLENGFSGELPASICNLKRLKRLVFAGNSFAGMIPNCFKGLKELLILDLSRNSFSGTLPTSFGDLVSLLKLDLSNNLLEGNLPQELGFLKNLTLLDLRNNRFSGGLSKNIENIQSLTELVLSNNPMGEEDMVGTNWGKMSNLVVLDLSKMGLRGEIPTSLTNLKRLRFLGLNNNNLTGFVPSKKLEALPCLGALYINGNNLTGELRFSTKFYEKMGRRFKASKNPNLCQPLEMVMSESHKHLSPLGVKPCT
The following text describes a protein:
Function:
Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules. Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore.
Sequence:
MSDALSTLQRSVLEKYRTLADCLHELNDTLVELNTDSDTNPEQVLAQMREIEVKIALVGTLLKGSVYSLVLQRNMGKQAPGGKAK
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MESGRLFFNSSTCHGNMLFLGNCDPVFRGARTMISMEETSKRRPFFSSPEDMYDEEYYDEQLPEKKRRLTAEQVHLLEKSFETENKLEPERKTQLAKKLGLQPRQVAVWFQNRRARWKTKQLERDYDLLKSSYDSLVSNYDCIVQENEKLKSEVASLTEKLQAKDATTEPVIGQKPEPLPADIVSSLQFSVKVEDRQSTGSAGSAVVDEDAPQLLDSGDSYFPSDEYPGGCVGPVNRLQSEEDDGSDDGRSYFSNVFTATEEQQQHEESLGWWVWS
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSDLKAYLAAKYMSGPKADAILARSSDPTLKKKRKKQQTNEDYIGGSVKAEASGGLMLRDEDEVWGRSKNEDEEDDAPVIGKDLATFKGSKSSWATVANKSALPLPQAEPTSPQDIKPDIKEEPDIDGPAASAPVQMTKRRGGLRTAAQLKEDTERELAEQRSPSPAEGEERPDPTETVHRDATGKIIDVKKRQEEERIREEEERRKEAERKEWTKGMVQRRDREERRRLEKKMAEADVGRSKDDVRMNKEMKEEERWNDPAAAFLTKKKKKGPRRPKYEGPWAPNRFGIAPGFRWDGVDRSNGFEKKYFQAQNTRARREYEHNQWSVEDM
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAELPTITEFFRGKNIFITGGSGFIGKVLVEKLLRSCPDLANIYLLMREKKGKNLEERIKLITDLPLFDQIKSKNPKILDKIKIINGDVTRLGLGLTPADRQLFVHNINIIFHGAASVRFDDALSDAVLLNTRGTREVVNLALAMKNLLTFVHISTTYCNTDRKVIGEQLYPAHADWRKTIEIAESVDRHALNILTEKYIHPLPNTYTFTKSLAEHVVYDLCKGKIPAVIFRPSIVISTAHEPFPGWIDNFNGPVGLLVASGKGIVHTVYSDPDVIADYVPVDILAKAMIIAAWKQAVKTKSPERLNPVFYNGSNNDVQPITMGDMVEMGKGICEDVPFNDVLWYPSGSVNKCYYAYLLKVYFYHLLPALIIDGLLKVMGKKPMLVKIQRRIYVANMALQYFSRNQWEFLNDKSVELQKDLLEEDFGSFQYGEDDVEPYDYFVKATIGGRRYLLKEDDDSLEQAKRHSRRMWIVSKIFSVVWYLALAWLIFVKVDIISVIFNKYREFCVYLLSE
The following text describes a protein:
Function:
In its hexameric form, promotes the accumulation of sec-16A.1 and the COPII subunit npp-20 at endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER), to positively regulate secretory cargo trafficking from the endoplasmic reticulum to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) and Golgi apparatus. Required for the assembly of proteins, such as the GTPase rab-6, at the Golgi apparatus. Plays a role in negatively regulating cell death and promoting cell and body growth.
Subcellular Localization:
Endoplasmic reticulum. Endoplasmic reticulum-Golgi intermediate compartment. Mitochondrion. Note=In oocytes, co-localizes with sec-16A.1 at endoplasmic reticulum exit sites (ERES). In proximal oocytes, localizes to a cloud-like region at endoplasmic reticulum exit sites that spreads to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).
Sequence:
MVHSNGAITSTILKARHADVVRKTSLHHANDLTLIDLVLNVQRLLALPSDANFVLKYKDEEGDLVTLAEDSDLLLALHTSGATLDVTVVVDSRAREAVHDVQKQVEQIKLDVGKLLGALSALDVAQIAEQSNTSVANLSAPKQSHHDNIVFQKSFEAAPPSPVPSEKAELPATIQPSVHEQFNHRPAHVEEEIPLENHYAPPPHQQIPDDLNTSFSSQPPPPIEQFGAIPPPNATIPSFPTSNAASPPVQEFAPPPPQQQQQQFQAPPPPMASHSSISSTPVQQQGFAPPQQFGGPPPSGPPSEYGGYAPPQQQQQQFGAPPPQGAPQQGFGAPPQGPPQGGPPQGSFGAPPPQQFHAPSPQSFGGPPPPVSSAPGNFAPPPQSGPPGAFAPPPSAFGAPQGPGGPGGYGPPPPGGPGAPGSYGPPQGGPGGFGPPPPGGPGAYGPPPTGFPPVGAPPPGAAGAPGGNPFARGPSATGYRQSPYQQ
The following text describes a protein:
Function:
Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
Subcellular Localization:
Cell membrane; Lipid-anchor. Cell membrane; Multi-pass membrane protein.
Sequence:
MRFKDQVHFIRRNMKKNRLRVFMTILATTMACAFLVVLSSVGFGIQKTITDMTMSQQIVTKVSVMGKEGDKPIKKADLEKYDHVRSVVERTQVYEPNKATLGNRTNESSNLIFTNMNDELKANMELEKGRVAKSENEIVVGYDFAKRLLTKKESEEYNKKIEEAKGNPEDIKEPKGYTKDILNKTIELSVSKTDSKTGDVTKTKTYDFKIVGITKKPSQDWMEDSNIFISDQFKKDFSEFLDFKGGNVETNIGVFADKFENVEQLTNDLTDDGYYVTSVTTELEGANTFFMVFKIGLIFVGCIAVIISAIGIFNTMTMAVTERTQEIGIMKAIGASPSIIRRMFLMESAYIGILGCVIGIIISYGVSYLVNLAVPMILAATSGGDAGDLNYTFSYIPASLVIIAVVICGGVAVISGMNPARKATKTNVLTALRREL
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase.
Sequence:
MSENTFPVYKVDVIVQFYRTEVLTGQESKHFTKNDLTPTPKPESVQRLYMRILQLLFRFRPECHYTVPLSENIQYPMLYESFAPIMSVYMRMCQFLPVCRVYDFSLSDLLNPKTKRTITILSAIQNFLHFRKQRLEITAAHQQSFRADMDRLQAYTREIKEAEKKIEKLTTIPPEQQAEAKELASALAELSTNTQHEYQDVSAINEKVAQFKTEIAELSQKLTQRKVEVATLKDEISKLKSQIVESPEELKNEMERMRETAKNIKMSKELADERLVELQMLVQCASQVEAEIQILLKQLQDLQSSMSKTKQRKEEVQSLEVMNESLQKELKSLSSEEAQLKRALTMKLDKESKQQIRRQKKKEVKDQQVKNIYGQYDKMHQKRQEIVKKIEECNRETKQFKEKMQALRENCNQRTQKAQEIYERLLTTLEQYHKRIEKILVETNADALKMKSHF
The following text describes a protein:
Function:
Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm, myofibril, sarcomere, I band. Nucleus, PML body.
Sequence:
MAKAPGGVGVGALSYKAPKALWPAEAVTDGTMADTEAVQRATELIDQRLAEEEENEVFLAEGFADNGRLRLQPQELRDCGKLRGTTHGRKLPMDKLVLEDEKKHGAQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKREALAAPQEPPPEPEEITGPVDGETFLKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLESGATVDFQDRLDCTAMHWACRGGHLEVVKLLQNRGADSNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPALEQNGLEGSAESGRETPQPVPAQ
The following text describes a protein:
Function:
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.
Sequence:
MDERKIRILQAIIKDYINSGEPVGSRTIAKKYDLGVSSATIRNEMADLEDMGYLEQIHSSSGRKPSDKGYRLYVDKLMTLTALTEREKMLIKDQAIDSALYEIDKTIRHSISILSEITKLTCLVKTPSMIKSRLRSIQIIKVDKYNLLLIVITDNAMIKNTLLRVTKEIDEGSLIKINNLLNQKLKGLNLREVNLELLNELKKEMTGYGDILKNILSSIYEALTDIEDAEIYMEGTTNIFNYPEYNDVDRAKEFLSMLNDREKVEELLYVDSDIAVKIGKENFVEDAKQCSVISAVYSIGKTPIGTIGVIGPTRIPYEKIISAVATIVKEINDTLTNDKNIHK
The following text describes a protein:
Function:
Involved in recycling plasma membrane proteins internalized by endocytosis. Required for recycling of the v-SNARE SNC1.
Miscellaneous:
MISCELLANEOUS: Present with 2700 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Bud neck. Cell tip. Note=In unpolarized G1 cells this protein is found in patches in the cytoplasm, while after bud emergence it is concentrated in nascent buds and at the mother-bud neck. Accumulates at the shmoo tips of cells treated with pheromone. Localization depends on an intact actin cytoskeleton and a functional secretory pathway.
Sequence:
MDDLLKVPEIVTNIASYLSTVDYLSFQQVNKRVYAIINGKNDSKYWSLKLTRMGLQQVHSNEEEEITLLDENDNQNSLRIFEIYKSFTAQNSKKIFVKFYRCYNSYARKLYNNNLANFFPTSYSNDPLKQTRILNFIKKYNFSNKNDIETFTRIETNFNILREIFINSVLKESELNYQSNNLAAVARFMKILLISNEESNAIEFFKSKADLPPSLTVLPSNDELFWAEQPREEDSGGSTVIFNSKNLDTFLNQLRDFLNEKIKLADILFKDEFPVILQFIESFIQDILLDILNNILLSYSEFLKENGKDSKANYECVPELYFTFIKKFDTELNDSVNAGANFRKVVRDLLNLYLEPFVVNYMNQTTRVFESLINSQLANYDTQVQDKQREQNAKIYNTLKDQTDASSASNNELPNDLSIITETSKTVPEADSKPSTIHQSVHSTDISNDKLDFLSSFTKIFKFSNNENQRLKQQLQLAYNLNLISNNLQNIKSLISLDLCYKILQETSEKTDQIYKFHTIESLLPLIKLRCQEIFKILITQLNKNHVKPAFEKAILLLQKYNPNEIEQIEIKFNSLSPANTQVEPLVQFTELINIGDIILQMISIFYKNELIPKKIIDKNKDFLNDVIQLKKNFETSIDDFVAEGLNIGINKLMDEISFVFKTLQLPDDYNPPPPSRNSPIRDIKPTKCAIRVVELLSNHCFLLTGATDKGTIDVYQQEIGERFFNEIVKHLKKCFISTEGAIWLICDLNYFYDFIANKLKQKNVVPYFVGLKSIGQLYIISGKDSKELGKLISDLGKFNGIFTQEEIYEFVQRRSDWVRVRKDVEKVMYGLGIRDCCIM
The following text describes a protein:
Function:
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
Sequence:
MTKIGLEIHCQLTNLESKLFCSCKANYRQFEINENICPVCMGLPGSLPRLNQDAVKKATMIAMALNCSTPEKIAFFRKNYFYPDLPKNFQITQLNIYGDTSVGGPGSIMVGDKEIRITRIQLEEDPGRLIYEGTSSKNQITLVDYNRAGTPLVEIVTEPDFENPKQVREFLNILSDLLENLGVSDPSLEGAMRADANVSIEGGKKVEIKNIGSFHDLEKAVHFEITRQESLHSREIEIAQETRHWDDKRKITISSRSKEEALDYRYFLEGDIPWVTIDPAIQEKLKSEMPESISSKKERYVSKYNIPNQVADVLSSDKFYSDLFEDSHTESNAKEIANIITTDLMGLVDTREKREASKITATHLRDLADAIQTGKISRNSAKNALHEIVKSGKELSQVMSDLDLGNVSDESELLTVIKDVISEEPQAVEQAKSNPQTINYLVGKVMQKTKGKADPKLTLDLLKKQIE
The following text describes a protein:
Function:
Involved in disease resistance. Required for resistance conferred by multiple R genes recognizing different bacterial and oomycete pathogen isolates like avirulent P.syringae or H.parasitica (downy mildew). Required for the establishment of hypersensitive response (HR) and systemic acquired resistance (SAR) after infection with the bacterial pathogen P.syringae DC3000 carrying avrRpt2. Required for resistance to the soilborne fungus V.longisporum. Interaction with RIN4 is required for the activation of the R gene RPS2 and RPS2-mediated resistance.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MNNQNEDTEGGRNCCTCCLSFIFTAGLTSLFLWLSLRADKPKCSIQNFFIPALGKDPNSRDNTTLNFMVRCDNPNKDKGIYYDDVHLNFSTINTTKINSSALVLVGNYTVPKFYQGHKKKAKKWGQVKPLNNQTVLRAVLPNGSAVFRLDLKTQVRFKIVFWKTKRYGVEVGADVEVNGDGVKAQKKGIKMKKSDSSFPLRSSFPISVLMNLLVFFAIR
The following text describes a protein:
Function:
The homodimer mediates transmembrane sugar transport down a concentration gradient. Transport is probably effected by rocking-type movements, where a cargo-binding cavity opens first on one and then on the other side of the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MALIERIGKALEPLMLVMGLISPLATMPQLYKLYVSHSEHALGLSLTTWLLYSFIALLWTIYGIYHKNPTIWVGNCLGFLMYVAMVVGIIAHTGGTY
The following text describes a protein:
Function:
Dynein-attachment factor required for cilia motility.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm.
Sequence:
MEQAEGIDFAALERELRAALEADRRYQRENDAKFRAVRQQVGSYEEFRDIVLASHLKPLERKDKAGAPRKQPWNSLALGSGQKELPDYGRIEESEFQPRTAAEFNRDWRRCRQSSAEKYRLLLALGGEQLGRIFSTEIGFGLLGEFLLVLSENFTPGDEVGITEVLRGLAQTQRFSLNVAFLSQTEREGSRQLFEKLLAAADTAGAMDDKTLLRPTQDNGTEKVKNTVKELRDLMQLYKLS
The following text describes a protein:
Function:
Through association with the adapter actl-1, may act downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input.
Sequence:
MDDSLGVSEVVMIPFMKREVLQQICAILDTDNTWETIAPYMPGIELRDVEGCKRYSSYNQSPSELLLRIWSSKGYSTTHLYQLFAKTKLIRLMRMMRSQVHEKYHYLENKVTNSTSRVSKQMVQPPGSQSASRLKKTEIKESSPSPAAAAASQLSRSNTDDTLRVAIEGTLPVTYCELLEATNGFAVSNVIGKGGYGTVYKGELKGTGGIVAVKRLHSGNDTSQNGSRERLRQSLTELRTLARFRHDNILPIYAYSLEGSEPCLVYQFMSNGSLEDRLLCRKGSVPLTWIQRKEISIGAGRGLGFLHSFGKTPIIHGDIKTANILLDKHMEPKIGDFGLCRDGHVEAEAMEKHPLIASHIKGTLAYLAPEFITSKILTTKLDVYSFGIVLLEIASGQRAYSDSRETRGLVEYCQVNKELAAHRKIPVREIFIDRRAPPLVGDEEKSFLDALIEVGLAGANNDRKVRPTMSQIVEYLCKNSIPPVV
The following text describes a protein:
Function:
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but also occur in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Subcellular Localization:
Mitochondrion. Nucleus.
Sequence:
MATSMAVVRQYLPRTCERLSVLQLPRIRHGENSLLVKMCGVRQLPFRQYSDKVLEGMGEFEEAEDQLDLSLLDQPAVRTPPRDRAWQRTRWWHAKQYAAMGKASGVDPAIMWPTKSELSKLIKEEKEYFPSLRAMQAEVAAEKQAADLERLKREKLIAGNMAKMPKMIEDYWQKVEEERAKRREQKEKRNRLLALAKEKLGYAVDPRSPRFKQMVEDMEAEEKKKRKELKKRGIKV
The following text describes a protein:
Function:
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subcellular Localization:
Mitochondrion. Plastid, chloroplast.
Sequence:
MTVAARALHHGRALQHLTGAGKIWQTDAANSNKLLQKLGIAQHCRVAHHSSHSLGAIRQHRKVSCSAGESRRVDPPDVADLAVRARLEVSSEEIEDWTPKIGKIIDWFGQLQEIDVEGVPPALRAGGDRTGNTVQKDEPRAFGNRDALWDAVPSKEGPFIRVPKILNESTD
The following text describes a protein:
Function:
Mast cell degranulating peptide. Causes histamine release from rat peritoneal mast cells in vitro. Has antibacterial activity against the Gram-negative bacterium E.coli K12 and Gram-positive bacterium M.luteus NCT C2665.
Subcellular Localization:
Secreted.
Sequence:
GLFSKFNKKKIKSGLFKIIKTAGKEAGLEALRTGIDVIGCKIKGEC
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
METVYFDSEEEEDNFNFGRFFEYEEEENNFNSGLFFEYDDNDGDDGFFDDGIQNLPITSPSSDSRSPLCQVITRESLWEAQRADLRMVMDLLLVKEHHARALLIRYQWNIDKLFIVFVEKGKAHLFAEAGVTVVEHDALSSGLSSTLVCTICIEDVPCNETTQMDCGHTFCNNCWTEYFIVKINDGMSRVIRCMEYQCNDICNEGIVRNLVRKRKPELAEKFDRFLLESYIEDNKMVKWCPSIPHCGNAIRIKDDAVCEVECTCGKQFCFRCLSEIHSPCSCLMWELWNKKCNKTNTSKWITVNTKRCPSCGKLVEKIGGCRTVHCFCGSIICWVCGKINGNLYHSCTLYKAPAEVQDANDYLHGVLRDTEEASYLDTISPERQKSGSTDSLLYETTGQIQSSRKISFGYLRYMHCYTHYKGHRNSIQMEAILEQKINDIMVLSSQENKPQSQDLSWAKIGVYRLIRSRYILSYSYVFAFYMFGDELFEGEMTETERIIKQNLFEDQQQQLEAKVVQLSDLMKKSFCEYTIDSLKQIKMQVMALTYTIDDLCKKMYDCIENDLLGSLQSYTHIIAPYGSKGVIRASDLAVHGVNGCLMEMGEASSCRDCIEGQEPSEKRAKIS