lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the sexual cell fusion of D.discoideum.
Miscellaneous:
MISCELLANEOUS: gp138a expression is much higher than that of gp138b and may well be the major gene for gp138 product.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MKIILILSIFLICFLQLGQSVIDPSQNEVMSDLLFNLYGYDKSLDPCNNNYVECEYINTTSTIQTVKSLSLGAPLHQYVITQDLTPLQNLTSFEVNEKIYLTSSFFNYINKFSQLERIVTYSLNLTIPDDTIFPAIFETFTIYKPSVPLSKVIFESPIKNLYVDSPLTGYSIPTLVNVNPYLGNLQLPVTYYSGFPSNLSQAFPNLQYLAIYVNNDMNQNNYHNFSISNIGVFKNLKGLDIEFTDSDNPQEFSIHSFLSNVPIIDNLYIYGQGVTIDPSVGIIDLSYINPKTFLKIQIQQTSLLNNCKGIILKSPKKASFNSYYNTFSYECIDFSNIADFSDYYNDYEQYLPNIDNAPLLTGVDIYQSVVVGDIPESYCRINYLSLYYNQLNGTVPSCIQCLGGVKGGDIVLPNPFLNFNKTTEPYCPTFKIDENYTHLVATDGTEKLIITGTNLGWDGNDITPIIANSKLGITIPKGVGTNKSITVTFQNGEQRTFNYSYVPPFIKSYGFLELDGHKYFTINGTGFDFVDSNNITINDQQITFDNAMGGGDNDGLIIFPIDELPNFATESKFTVSALVGGQSSNEVTFYYFNSINITEEKLVLNNTGGSVDINGSFGTNNTSLVSVSINGTNCLVTSYTNSKLTITYPSNQVGDNYVLTLNVGGYAVNLVVEYIEGGETPTPSTTPSTTPSTTPSSTPTQSPDDDGSTSSTLSTSFYLITLLFLIQQFI
The following text describes a protein:
Function:
Terpene synthase that converts its substrate farnesyl diphosphate (FPP) into the sesquiterpene beta-barbatene.
Domain:
Contains several highly conserved motifs that are important for catalytic activity including the aspartate-rich 'DDxx(x)D/E' motif and the 'NDxxSxxxD/E' motif, both of which are involved in complexing metal ions to coordinate the binding of the isoprenyl diphosphate substrate in the active site.
Sequence:
MYSIYDFKYPSDWIEPTADDKCIYDCYKEVINYKLLDENKQTFQYYYGTLSSTINFYPLCNYEQLVIACRFLTVGYLIDDFLESNLVDSETSNLMSKKIENILIDGEYLDQSNISNIEKYTMFFRGKARQFVGDKINIFNQFIKFFVEWINSINPFNKAINLNNYDSYNFFKKVNSGTYVTLSMAMLLNPNTKVDTNIWMNPRFERFVCNGAYQMSAFNDCASYAKEVRSNCHLTNPLYFLQKEIGSFDQVYKLILNFNNKIVNEICKDEELLLKECPDDQKDDLKYLTRSMKLILGGNYSWSLKCTRFNDIDSPFIEQRSINPDVIAYENIVDKIIKL
The following text describes a protein:
Function:
Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion.
Subcellular Localization:
Cytoplasmic vesicle. Early endosome. Recycling endosome.
Sequence:
MLSHAEMEERSSLPSVSIPCHNEQRDKKKRYTVYKVLVSVGQHEWFVFRRYAEFDKLYNTLRKQFPSMNLKIPAKRIFGDNFDPEFIQQRRAGLHEFIKRLVSHPQLCNHPDVKSFLQMDKRQHLADASEDEDDKNSSTSRDINLGPSGNPQAKPTDFDFLKVIGKGSFGKVFLAKRKHDGKFYAIKVLQKKVILNRKEQKHIMAERNVLVKNVKHPFLVGLHYSFQTTDKLYFVLDFVNGGELFFHLQKERTFPEPRARFYIAEMASALGYLHSLKIVYRDLKPENILLDHEGHIVLTDFGLCKEGISQTDTTTTFCGTPEYLAPEVLKKHPYDNTVDWWCLGSVLYEMLFGLPPFYSRDTHEMYDNILHKPLAMRPGASSTAWSLLQGLLEKDGTQRLGSNGDFNEIKVHNFFSSINWDDLVQKKIPPPFIPNVTSCCDISNFDPEFTEENVPNSICWTQSHSVVNASVMEADDAFLGFSYAPPSDDSFL
The following text describes a protein:
Function:
Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge.
Subcellular Localization:
Golgi apparatus, trans-Golgi network.
Sequence:
MAEGEEVLPLPTSSGDNWEKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALNVAGKGDSLASWDGVLDLPEQNTIHKDCLQFIDQLSVPEEKATELLLDIESVITFYCKSRNIKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSIEVTQAIWDGYLQQADPFFIYFLMLIILVNAKEVILTQESDSKEEVIQFLQNTPSSLNIEDIEDLFSLAQYYCSKTPASFRKDNHHLFGSTLLGIKDDDADLSQALCLAISVSEILQANQLQGEGVRFFVVDCRPAEQYNAGHLATAFHLDSDLMLQNPSEFAQSVKSLLEAQKQSIESGSIAGGEHLCFMGSGREEEDMYMNMVLAHFLQKNKEYVSIASGGFMALQQHLADINVDGPENGYGHWIASTSGSRSSINSVDGESPNGSNDRGMKSLVNKMTVALKTKSVNVKEKVISFIENTSTPVDRMSFNLPWPDRSCTERHVSSSDRVGKPYRGVKPVFSIGDEEEYDTDEIDSSSMSDDDRKEVVNIQTWINKPDVKHHFPCKEVKESGHMFPSHLLVTATHMYCLREIVSRKGLAYIQSRQALNSVVKITSKKKHPELITFKYGNSSASGIEILAIERYLIPNAGDATKAIKQQIMKVLDALES
The following text describes a protein:
Function:
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Also induces a decrease in angiotensin II-stimulated transcriptional activity. May play a role of negative regulator in cardiomyocyte hypertrophy induced by angiotensin II through an inhibition of p38 mitogen-activated protein kinase pathway.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles.
Sequence:
MELPAVNLKVILLVHWLLTTWGCLVFSSSYAWGNFTILALGVWAVAQRDSIDAIGMFLGGLVATIFLDIIYISIFYSSVATGDTGRFGAGMAILSLLLKPFSCCLVYHMHRERGGELPLRPDFFGPSQEHSAYQTIDSSSDAAADPFASLENKGQAVPRGY
The following text describes a protein:
Function:
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Miscellaneous:
MISCELLANEOUS: The porphobilinogen subunits are added to the dipyrromethane group.
Sequence:
MSSQQIRLATRGSDLALRQAGEVVDTLEDRRHDVELVEVETEGDRVTDALISDLGKTGAFVRALDQEVMEGTVDAAVHSMKDVPTEVPEDLVVAAVPHRENPADVLVTPDGTDLEDLPAGSVVGTASLRRGAQVQAHRPGLDVEPIRGNVGTRVEKLLAPALHREHERRTEAEKEAQSRDAREQRRGDYTADIEAGVENLDTEDGEEGAADDGDDTASSSEFEQSVTEWFDSLTPLQQSAMERDPDTEYDALVMARVGLERTGLLHHVGIEELSTGTHVPATGQGALCVTARRDSDVVDTLRDALEHVRTRVEVTAERVVLEELGGGCIAPIGVHALVQGDTIRTAVQVFSQDGSEQVGETRELDAEQYATDARELAADLRDRGAADLIEDARTEA
The following text describes a protein:
Function:
Catalyzes the transfer of the acyl moiety from in vitro synthesized 3-hydroxydecanoyl-CoA to acyl carrier protein.
Sequence:
MRPETAIIEIHGQYRIHTEFYGNPAAQQTIILVNGSLSTTASFAQTVKYLQPHYNVVLYDQPYAGQSKPHNENHTPISKECEARILLELIERFRAEVVMSFSWGGVATLLALAQRPGRIRRAVVNSFSPQLNPAMLDYLHRGLDYLAACDRTQIGNLVNETIGRYLPQLFKRYNFRHVSSLDEHEYHQMHFHIREVLRLNADSYTESFAGIEIPMLFMNGELDIYTTPHEARQFGQLIRGAEFHTIRNAGHFIDVEHKAAWQQTQDALLAFLRPQRTQPLNPIYRPQPNGASVPLAALAS
The following text describes a protein:
Function:
Catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPSKAPRKSLSVSFVWTFSILAVLRLTSASFRVIDDCDEVYNYWEPLHYLLYGYGLQTWEYSPEYAIRSWFYIALHAVPGFLARGLGLSRLHVFYFIRGVLACFSAFCETNLILAVARNFNRAVALHLTSVLFVNSGMWSASTSFLPSSFAMNMVTLALSAQLSPPSTKRTVKVVSFITIGAVIGWPFSAALSIPFILLELVDLKGRFRHLFCRWFKAIFVALLITGICITVDSLFYHRIQFVAWNIVKYNVLAKDGRGPDIYGTEPWWYYFANLSLQHNIVLWFAMACGPLVLLAAFTNWINLDSFLDLSSVISPFYIWLFIFIIQPHKEERFMYPIYPVLCLAAAIGLDMSLKLMIQILSSINETVRSKFPVRFVVLCVYAIIGCLSIARILAIQNYNAPMIIYPAISFLETDNNVTTNVCVGKEWYRYPSTFFLPDNSRLKFVKSEFDGILPGEFVESNSTWWNREGYYQIPEHMNEFNNEEPTRYTSLESCDFLIDLEFDHSKATVNEPIYSKSDGWIPVMVYPFIDTKQTPFMGRAFAVPFIEPKWGRYEILVKKPVKIDFSNLRRASKQQA
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1/sscA) via its interaction with PAM18/TIM14. May act by positioning PAM18/pamR in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein.
Domain:
The J-like region, although related to the J domain does not stimulate ATPase activity of mtHSP70. It nevertheless mediates the heterodimerization with the J domain of PAM18 and is therefore essential for PAM complex function (By similarity).
Sequence:
MAHRIVTQVVVTGARVFGRAFAEAYKQASAASKYQQKTGKSAGGSSSSGITLDEACKILNVKPPQAGETNLEQVMERFKKLFDLNDPQKGGSFYLQSKILRARERIEAEVREAERKAAHEKELKEGWKPKVYKDR
The following text describes a protein:
Function:
Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Important factor in pathogenesis, PI-PLC activity is present only in virulent listeria species. It may participate in the lysis of the phagolysosomal membrane.
Subcellular Localization:
Secreted. Cytoplasm. Note=Secreted and, to a lesser extent, cytoplasmic.
Sequence:
MYKNYLQRTLVLLLCFILYFFTFPLGGKAYSLNNWNKPIKNSVTTKQWMSALPDTTNLAALSIPGTHDTMSYNGDITWTLTKPLAQTQTMSLYQQLEAGIRYIDIRAKDNLNIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKILLLSENHTKKPLVINSRKFGMQFGAPNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLTFTPRQYAAALNNKVEQFVLNLTSEKVRGLGILIMDFPEKQTIKNIIKNNKFN
The following text describes a protein:
Function:
Participates in the control of the reentry into the cell cycle following pheromone treatment.
Miscellaneous:
MISCELLANEOUS: Present with 1540 molecules/cell in log phase SD medium.
Sequence:
MSDQINVLSMQQQQQQQQQQQQVYMSPQAENLNHMYLLVNKLVKQLRENQAEKAKILRNIDILSGSLNKYETSEEPHDTTENIALFNRFLEQRGKAPITEKEQLSNNLDENAKDDVMLGVLKRQNSMLRKSLQESKQVTLESMDLLSYSEDSLNYIVAQLRGNILMHHKETIKLIRQKFQTETIPLEDEEFKMYLENVNGLQKLTDISHTYRLLLRLHAQD
The following text describes a protein:
Function:
Regulates protein folding in the endoplasmic reticulum (ER) lumen. Forms a complex in the ER with SDF2 and MED37A/BIP1 which is required for the proper accumulation and function of the surface-exposed leucine-rich repeat receptor kinases EFR involved in pathogen-associated molecular pattern (PAMP) triggered immunity.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MAIRWSELCIVLFALSYAICVLAGKSYYDVLQVPKGASDEQIKRAYRKLALKYHPDKNQGNEEATRKFAEINNAYEVLSDEEKREIYNKYGEEGLKQFSANGGRGGGGGGMNMQDIFSSFFGGGSMEEEEKVVKGDDVIVELEATLEDLYMGGSMKVWREKNVIKPAPGKRKCNCRNEVYHRQIGPGMFQQMTEQVCDKCPNVKYEREGYFVTVDIEKGMKDGEEVSFYEDGEPILDGDPGDLKFRIRTAPHARFRRDGNDLHMNVNITLVEALVGFEKSFKHLDDHEVDISSKGITKPKEVKKFKGEGMPLHYSTKKGNLFVTFEVLFPSSLTDDQKKKIKEVFA
The following text describes a protein:
Function:
Acyl-CoA synthetase required for both the import of long chain fatty acids (LCFAs) (C14-C18) and the activation very long chain fatty acids (VLCFAs) (C20-C26) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. The transport and fatty acyl-CoA synthetase activities are genetically separable and are thus independent activities. Esterifies VLCFAs in the peroxisome matrix. The VLCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Lipid droplet. Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MAAIAKAAASLAAIAYLDAKHGIANDLLLSRGASGGEIRHKIRSWRNKLSIYEFFDYQATKRPDAVAYVYLGKNFTWGEVAKDVHRLANYLLSRGYKAGDRVAIFMGNSVAIVEWFFACMCINVIPAFINNSLTGKGLVHCVSVARAKLLVYEPYLEGVVSEVQDQLLDNSQIEGFLRYDDGITPVDGDTEKPPIEVAKPLAKKIEFGPSDLVKYSAKRIPDKYRKEVGESSTAALIYTSGTTGLPKAALCSHGRMGTACSVWPVFNSFSSKDRIYTPMPLYHSSALFLCICASLWSGSTVIIGRKFSARKYWDEVRKHNATVVQYIGEIARYLLAVPPSPLDKQHNVRMAYGNGMRPDVWEKFRERYGVRTISEFFASSEGNGALLNYNTGPFGAGAVGRLGTLARKVRPDFKIIRVDAITEDIYRDPKTGFCVECGPNEPGEFVMRIGTNSISKFQGYADNPEATSKKVLKDALAKGDAWFRSGDLMSKDVDGFFYFGDRMGDTFRWRSENVSTTEVANALGQVVSEANVYGVLVPKHDGRAGCAAIPADDAARVDWNMLAAVARKSLPKYAVPLFIRVVPTMEQTGTVKQQKVQLRNQGIQHDQCGTDRLYWLPPNAQGYQPFLPEHYKQIEAGKVRL
The following text describes a protein:
Function:
Aspartic protease involved in drought avoidance through abscisic acid signaling.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MAFPRFLSLLAVVTLSLFLTTTDASSRSLSTPPKTNVLDVVSSLQQTQTILSLDPTRSSLTTTKPESLSDPVFFNSSSPLSLELHSRDTFVASQHKDYKSLTLSRLERDSSRVAGIVAKIRFAVEGVDRSDLKPVYNEDTRYQTEDLTTPVVSGASQGSGEYFSRIGVGTPAKEMYLVLDTGSDVNWIQCEPCADCYQQSDPVFNPTSSSTYKSLTCSAPQCSLLETSACRSNKCLYQVSYGDGSFTVGELATDTVTFGNSGKINNVALGCGHDNEGLFTGAAGLLGLGGGVLSITNQMKATSFSYCLVDRDSGKSSSLDFNSVQLGGGDATAPLLRNKKIDTFYYVGLSGFSVGGEKVVLPDAIFDVDASGSGGVILDCGTAVTRLQTQAYNSLRDAFLKLTVNLKKGSSSISLFDTCYDFSSLSTVKVPTVAFHFTGGKSLDLPAKNYLIPVDDSGTFCFAFAPTSSSLSIIGNVQQQGTRITYDLSKNVIGLSGNKC
The following text describes a protein:
Function:
Potential calcium sensor.
Sequence:
MADVLTDEQIAEFREAFCLFDKDGDGCITIEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFGEFLTLMARKMKETDAEEELKEAFKVFDKDQNGYISANELRNVMINLGEKLTDEEVEQMIREADLDGDGQVNYEEFVRMMMAV
The following text describes a protein:
Function:
Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]) (By similarity).
Sequence:
MAQVNIRRDVEDQFYRYKMEVLQGKVEGKGNGIKTVIVNLPNIARDLDRQPEYITKFFEIEFNAKSNIENEKYSINGQYTVERLASALDKFISKFVLCSFCKNPETKFVIKKGVIEFKCAACGRVGPIDMKHKLTSYIVKNPPKAVSTKSTHDEALAQQPQIKKEKKSKKKKDDDDEEDDVVWFTDTSEKAAEERKKKAIGDSTSAVISMMADISVEPQSAKEEQDEDDEQEEGQEKESDPVSSISSFLETNPADQELMEKLDSVQEEFGLRSSATSKAAIEALCKNAENTIKFVKTQTALLKKISKRRDGKLGILLGFEELCVKDETLLKSIQGILKNLFDAGILTEENILKWYHQKAKSKVVIKACKDFIAWLETAEEEEEDEEEDEEDDS
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MSKDANPKEALIKAAYADVNKFGNNQEFDKAVKAVNRILGVAPDDPTALHCKVVCLVQLSKFEEAYKFIEKNRLSSLFFEKAYCEYQLNKQQQALKTIDDAGLQPLPPNLKELRTQVLYRLERYDECLDSYRDIIKNTSDEYEEERRTNLSAVAANLAVDQTKEVPEVPEDTYEQYFNSACIQANRQKYAEAERKLRTSEKLCLEDECASEEEIIEEVDVIRVQLAYVLQLQGKTKEASSIYADCLRHKPKDAALVAVASNNLVVVNKDQNVFDSKKKIRAALADACESRLTSRQKQVIALNNCLLALYTNAGDQVQQLSQKLAQTYPQVEFEALLIRCTQLAKDRKHKEAIEQLQKFAAAHKSHEFVSKFAIIQLQLLQGNRKDAIETLLSLGEAKYKPGVVSALVSLYLGTDNKTAASALLKSAVDWYKKNEVSSGDLSDMWRQAAEFHLRGGASETAASSLEELLKLNPNDTKVLAQLVIAYAQFQPKRALELSRKLPKLETLTTASEIDALEAANWVMSAKAAKKTANTKVEPSPSTPLEKKKNRNRKRKGKLPKNYNAEVAPDPERWLPKYERTGFRKKRGGARGKDVIKGSQGMASGAADQYDMSSRVNLTKNSPATPVYQETAPGPRQQHRKGGHKKKKGGRF
The following text describes a protein:
Function:
May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein (By similarity).
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MNMIEALLSMRVLFLTQVFGIFLCFPGLTKAGHLHYHSSIEVVIPMKVTEKTRGMNLPNWISYSLKLGGQRYIIHMKIKNLFLTRHLPVFTYSDQDSLLEDYPFVQDDCYYQGYVEGDSESLVSLSSCFGGFHGLLEINNIVYEIMPKKFSRKFEHLVYKVDINKTESRGSSLMQDNITCQVELQKSGNPILKQSSFEDWWTHTKIVELVVVVDKTLYDHYGNYTVMLSDLYSVINIVDTIYEVIGIKILLVGVEVWNKKNLIVIDDVSKSLRLYCRWKASNFLHRLKHDVSHLFIYRHLRGLSGIGSTGGICDPKRSCAVVTFIDRTLNLRAIGVAHHLGHNLGMKHDEDICKCSYSKCIMHMDSPPIPKFSNCSYNYFWSYTVKNTRCLMENMYTKDIFDRTRCGNGVVEDKEQCDCGSLRNCTNDLCCMSNCTLSTGSSCAFGLCCKNCQFLPSGTLCRKRDNICDLPEWCNGTSHECPDDAYVEDGIPCGVSAYCYEKQCNDRNEHCRQIFGQNAKTASVHCYREINTKGDRFGHCGLQGPTYIKCKSNDALCGRIQCDNVVQIPNMKDHSTIHFALVKNVSCWGTDYHTGTSLTDIGDVKDGTECEQNHICINRHCVHISTLDSNCTPAFCNYRGICNNKHHCHCNFHWDPPNCMIRGHGGSVDSGLPPKTNKKKHFFYLLLLQLIILACLLSCLLWLLFNIKGSKRKPQVQPTPVKTKKVSKKVPSQKPSPVPSPSLPQLRMPSRSASPTSSIKSTN
The following text describes a protein:
Function:
Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAVEQDPKVQIEQSIEAGTKFCNIFYEHFDKTRHRIGKMYHDTAQLVWEGNGVVGKANIEKYLQDLPGCFHRLDWFDCQPILSQFTSGKETIVVATGGTVKYDSHPMRGFMQNFMLTNVDGTWKIITDSFRLQKTFVQS
The following text describes a protein:
Function:
Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of transcription.
Sequence:
MPLAQLVDLWPEVELVHEDTENGHGGPEDRGRHTSKANINAKDALVSCVFGMNRNASKIREKMLRQIFRTKTSIKEDEVVVKEIPITHHVKEGAEKADQSHFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHGADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNATNRLGSGVEGAEELKRHPFFSTIDWNKLYRRELSPPFKPSVTQPDDTYYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVAPVLVEEDAKKTSSPPVLSVPKTHSKNVLFTDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKSKRDPSEEIEILRRYGQHPNIITLKDVYEECNSIYLVTELMRGGELLDRILRQKFFSEREACSVLFTVCKTVEYLHSQGVVHRDLKPSNILYVDESGDPESIRICDFGFSKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPGDTPEEILARIGSGKFTLRGGNWNTVSAAAKDLVSRMLHVDPHQRLNAKQVLQHEWITKRDMLPQSQLNRQDVHLVKGAMAATYSALNSSKPTPQLQPIKSSVLAQRRVKKLPSITL
The following text describes a protein:
Function:
Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP and dTMP), and no activity against IMP, UDP, GMP, AMP, UTP or pNPP. Appears to function as a house-cleaning nucleotidase in vivo, since the general nucleotidase activity of it allows it to protect cells against non-canonical pyrimidine derivatives such as 5-fluoro-2'-deoxyuridine monophosphate (5-FdUMP), and prevents the incorporation of potentially mutagenic nucleotides such as 5-bromo-2'-deoxyuridine (5-BrdU) into DNA. Is strictly specific to pyrimidine substrates with 5'-monophosphates and shows no activity against nucleoside di- and triphosphates.
Subcellular Localization:
Cytoplasm.
Sequence:
MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYYVPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLSGAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALFYEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVYSYQDLLDCLDKNILEKITF
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
Sequence:
MENGVNELENDEFEKLLGEIPNVTSGNSYSEESGVINCPKDFNLTSSNGDGSKPIGVTETYISNEILGKLKEFGNRVEQLPNKRFESEEINLPNEQAIVSAFAELRVKDGAFLESAAPMANSTPLLNHLAVVNGQCKNSLGKIPSNLDSQVLVVPSTRTPNNLSNAFNGFSPSIGGHQSGYVHTMENISAAVPLPPGVPGVHLLPPIHRVDIPVISNQQHYFLDVTSPVPYFHSQINRHHGACRHIEEEQHYFLYMQQLRAQQLGNQYPIQPDGSITSRSINSSSRQPFSEMPIPHFNQQVSRSINPLNSLFCSMGSDVLQGLDKTDKQYFPERMLRRSHGPEPVKSAKFGSFGGTNYLSNMNRNRRVFPNAYSKRSFHSPSAESRLDCLESRSFSPDAVDLKFHRWSQSQEYNLIDDFAGRIYLMAKDQNGCRFLQRKFAEGSSEDVEKIFPEIIVHIVELMIDPFGNYLVQKLLEVCNEGQRMQILRAITRIAGDLVRISCDMHGTRAVQKVIETLKTPEQFSMIVSSLKPGLVNLIKDMNGNHVAQRCLQYLTPEYREFLFEAAITNCVELATDRHGCCVLQKCLSQSDGGQRHRLIYEITSNALVLSQDPFGNYVVQYIFDIRLPWATTNIFDQLRGKFGDLSMQKYSSNVVEKCLKHVDEERSSYIIEELLSDPRLDQIMQDPYGNYVIQAALNISKGALHAALVEAVRAHVPVLRTNPYGKKVLSCNSLKK
The following text describes a protein:
Function:
Involved in cytokinin biosynthesis. Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP.
Sequence:
EIEPDTDFTAEDFCLQAIIYIEKILKTQRVPIIVGGSNSYIEKLVEDPVFMFKYKYDSCFIWIDVEHSVLNRRVDIRIDQMVKAGLVDEVRQIFIPDADYTKGIRRSIGVPEMDRYLREETNIDGDDESKKMILQASISSIKRNSRMLYCNQLEKIQRLISEKMWSVHHIIATDVFKQDREEDLDEAWTNIVLQPCLDIVKRFLKNDHHNIIIECT
The following text describes a protein:
Function:
Involved in RNAi-dependent heterochromatin formation and centromeric silencing. Required for the conversion of centromeric pre-small interfering RNA transcripts into small interfering RNAs, histone H3 'Lys9' methylation, and the recruitment of the RITS complex to centromeric sequences.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Sequence:
MGKVSANNQSGFFKFYIDTALLLNAEFISSFTNCINSEYNGKVKISYSSSSQQFKVIVYEEHKREAFSLFEEIVQKLKRESTVYKKPRLDIHPFGQLHYDFTTLLNFQRYLDLGYGIEDVKIKENEDIVKSKVGKKPTSSDFYIPCLIKPKIITPFEWEGNFKQVIYSPTVYNGSFKRLFYLPDNNDLLKEFAHATNTKYKASLKDNKIVVLANNDQDINAMLEKMKHIENLVSQKVYEYPEETLVYAGKIAPCQLKFLKLKFENEILYTAMHTTSIFKSVFNILGSFYTMRLLRNKHDGDSYELVPVFAKNPSKTPPCNDNFKIFSDDIKLIGCKIFAGVSLNFSSPKPAHRFYELNKTSSNLSIPVLQKPSNFHSSSTELSDNSIHQGRRAVDPVVNQNNPSNFEEMIMNKLNKLPTIDKQILGTSSLTHFQDKTTAIEHSINKSNSKQPPRFKFQLPPRPTSNTLPLEPEEELVTRYSVSSDGNTVDEAITKQSQTFQLVNSNEFNEVNANDVHKSLRQNCAKLDFDDSKSKNLLSVECLELDKGSDCSTPKSGSLTPSIDMKFLRLQDEKMDDLGDNYYTILMSSNPVSSYGVGSLYLFQPKIVCSEKYINHEEIDNMNLKSLHRWLSRSLHVLQSFSGEIELNLEFGVILYPNISSDVSACSHGFMNIYKDLNLPRSYFADCITKSVSNIDSLLNTPVKILFGRTEYTYPLIEHEVLDSKNYFVFKGSLLFTDDKRNKTEDSTVFFSMICSSKLDQFAFYKDSKQSSTCTINFPLALWDSRLRIETKVPLNDAILTEFSKSIRFRNVNKDLLLVFGNMEDRVIIHSVTRINENSVPFNKNLLPHSLEFILKCSKVKSYDISPSSINSKEAFVCLDRSKESKPIESCFSLSIQSVYMQSQFKYNNSIRAGETAPWKLANKQFIGGAITENVSDLYTAAIIMVNQLGGIHPTI
The following text describes a protein:
Function:
Catalyzes CTP-mediated phosphorylation of dolichol, the terminal step in de novo dolichyl monophosphate (Dol-P) biosynthesis. Dol-P is a lipid carrier essential for the synthesis of N-linked and O-linked oligosaccharides and for GPI anchors.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTRQCPPQESGAALSGSVLAEAAVVFAVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGNAVFQFRMSANSGLLPASMVMPLLGLVMKERCQTAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCAISGLAGGVIIYIMRHSLSVGEVIEVLEVLLIFVYLNMILLYLLPRCFTPGEALLVLGGISFVLNQLIKRSLTESQGDPVDFFLLVVVVGMVLMGVFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHWLIRRNPLLWLLQFLFYTETRIYLLAYWSLLASVACLVVLYQNAKRSSSESKKHRAPTITRKYFHFIVVATYIPGIIFDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLIPRPCTQKDSLEGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Mitochondrion.
Sequence:
MIRYSLNGIRLFGSLNLFNATRILPISLGRASYAHARLFTSKVEKSGTAEESALPSVDEEEDKLNSLLGNIKVRTAQEDGVSVEEVLMHHPELLRNAPHALQQSVKEILASKEVGDAFKKN
The following text describes a protein:
Function:
Catalyzes the transamination between an unstable intermediate ((S)-ureidoglycine) and the end product of purine catabolism (glyoxylate) to yield oxalurate and glycine. Glyoxylate is the preferred substrate, but other amino-group acceptors can be used.
Sequence:
MSGRRELCTPLRTIMTPGPVEVDPRVLRVMSTPVVGQFDPAFTGIMNETMEMLRELFQTKNRWAYPIDGTSRAGIEAVLASVIEPEDDVLIPIYGRFGYLLTEIAERYGANVHMLECEWGTVFDPEDIIREIKKVKPKIVAMVHGETSTGRIHPLKAIGEACRTEDALFIVDAVATIGGCEVKVDEWKIDAAIGGTQKCLSVPSGMAPITYNERVADVIAARKKVERGIATQADRAALSGNRPITSNYFDLSQLEDYWSERRLNHHTEATTMLYALREGVRLVLEEGLETRFERHRHHEAALAAGIKAMGLRLFGDDSCKMPVVTCVEIPGGIDGESVRDMLLAQFGIEIASSFGPLAGKIWRIGTMGYSCRKENVLFVLAGLEAVLLRHNAGIEAGKALQAALDVYENAGRQAAV
The following text describes a protein:
Function:
Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
Subcellular Localization:
Secreted.
Sequence:
MEKLSLCLLVIISLSNAFAQTDLSAAMKSRNDFQPFLKREKRERPLFGLSSIFFSGVQDMIGKAFVFPKESENSYVSLTARLTKPLTAFTVCLRVYTDLNRDYSLFSYATKTQYNEILLFRGKTAVYSISVGGADVIFKPHQSSEPMHFCMTWESTSGITELWVDGKPMVRRSLKRGYSLGTQASIILGQEQDAFAGGFEKNQCLVGDIGDVNMWDYVLSPEEINTVYAGGTFSPNVLNWRALRYEMSGEVYVKPQLWP
The following text describes a protein:
Function:
Branched-chain amino acid transport system which is involved in the uptake of isoleucine, valine and probably leucine. Can also transport threonine, and is active as a minor serine permease. May be an amino acid permease of rather broad specificity, because several amino acids, albeit at 100-fold excess, are able to prevent isoleucine uptake. Probably does not transport methionine. Together with BraB and BrnQ, plays an important role in the activation of CodY, a branched-chain amino acid-responsive transcriptional regulator that controls the expression of several dozen transcription units in B.subtilis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKGSVFRKKSIQDLIAATSGEKSLKRELGAFDLTLLGIGAIIGTGIFVLTGTGAVTAGPGLTISFVVAALACLFAALSYAEFASSVPVSGSVYTFTYATLGELMAFIIGWDLILEYMLAVSAVSVGWSGYFQSFLSGLGIHLPVALTAAPGAVKGTFTLFNLPAFVIVMAITYLLYLGIKESKRVNNIMVILKILVVLLFIAVAAVYVKPHNWQPFMPMGFGGVFSAAALVFFAFIGFDAVSSAAEETKNPAKDLPKGIIFSLLVCTILYVTVSAIMTGVIPFAQFAGVDHPVSLVLQSAGQNWVAGIIDIGAVLGMTTVMLVMLYGQTRVMFAMSRDGLVPGSLSKVHPKHKTPYVATWFFGTMSALLGSLVPLDELAKLVNIGTLSAFVLISVAVIVLRKKQPDLPRAFKCPGVPVIPGLAILFCLFLILNLGWVTIVRFLVWLLIGLVIYFLYSRKHSKLNQ