lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MLDCDVFSVSSIIADIVQYRNMHQGLQHLVTRFQDVDNVEASDRSVKEGLLSLGVHFAANYNEHDEVYSIVTSVTEIAYKAEYVTDSCLVSSHPLWYESHWISEVVKNIKLLTKVVSESCNRKKIGVTMHEVAKPPINLEAMGKTKKHLLRGSSQQDIISIVGMPGLENTIVAEKIYNDLIVIHHFDGHSKCRVTQVYSWKELLLTRLNDVLDPTDALKQKIDVWDKTTWDNLYMCFNANYVKRESNPHHLRLLRDDESCTLLQEEVFQGESCPPELVDVGYRIAKICVALPLFVVLVPGVLKEKEKKIDLWKQVEESLGSKNIGSLEGSMSLIAFSYKNLPHHLKRCFLYFGGYLKGRDIPVSKLTRLSKVEGFVQANKEKRTETAQDFLEDLISRNLVMVMEERANYKVKRCCIHDLLHNFCFQKSKRKTSLTLNRYWKFLNHSYQDEIDLWQPCSSNVQSLQFKMIDPDNLLWPRDLSFIFDSFKLVKVLDLESFNIGGTFPSEVQSLIHLKYFAVQTDANSIPSFIAKLWNLETFAVRIRTRSDITFFYSKDDQIEAFTIYYLETFSAPHLFYGEDAEMILTKMTNLRKLSCIFSGTFSYSEKVKGRCVHFPRLEFLSHLESLKLVSNIDPAKLPQEFNFPSKLTELTLSKFRLPCLNLNLYNINISQWSISDDAFPKLERLVLTKCTQLEEIPSPFGFFVANSALRIQTTQHEDMANNMFIVTIHPLDWTR
The following text describes a protein:
Function:
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
Sequence:
MNNKQRYQNWKKARSDKRDQKQQQGHQQQITLHQLQQIDNQQSNSQDESEDEDQQQITKKEERLNDIKLFMIDYGQCDVKKCTGRKMERFKLLTAIKPKVKFQGIIVSANGKKYVSKEDEELLQKGICVIDCSWAKVEEITYVSPNERLLPHMVAVNPVNFGKQFKLSCVEAIAATLALCGRREQADYILSKFTWGENFFKINKEAFDLYAECQNDKELKVAELKYLEMAQKKENTGQKNYDMPSSSDEDEDQIQ
The following text describes a protein:
Function:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Sequence:
MDPQLMEVSQQFERFKAAFIIKDFDTCSSLLSQLKLFDHYLISLSLNALLLLTCALFFLCTRNRIPPSPQENLIMGLNLLRLLVQNRIAEFHTELGLLSSATLENPCIKHAVELEQSFMEGAYNRVLSARQTAPDETYVYFMDLLAKTIRDEIAGCSEKAYDHLSISEGCKMLLFSSDQQLLTYVNEEHPEWEVKDGLVVFQKTRETAPCKEIPSLQLINQTLSYTRELERIL
The following text describes a protein:
Function:
Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Colocalizes with microtubules around centrosomes in prophase and with the mitotic spindle at prometaphase and metaphase. From late prometaphase to anaphase, is highly concentrated on kinetochores. Located at the kinetochore-microtubule interface. The astrin (SPAG5)-kinastrin (SKAP) complex localizes to the microtubule plus ends.
Domain:
The coiled coil regions mediate binding to kinetochores.
Sequence:
MAAPEAEAQETAFRTTGPPTDSEPRPFPPSSRKFPFESAAADSNEDWAVAAEHYLKGSGENGGWEQPAPGVQPSHPATMASAKTVCDAQPHSMPSCGLPADTQTRATSKLPVKSKEADLLRHLHPGGPEPDVTKVTKSRRENGQVKAAETASRRNLRNSYKPFNKQKPEEELKDKNELLEAVNKQLHQKLTETQGELKDLTQKVELLEKFQDNCLALLESKGLNPGQETLASKQEPTTDHTDSMLLLETLKDELKVFNETAKKQMEELQALKVKLKLKEEESVQFLEQQTLCKDEASDFTIILEEMEQLLEM
The following text describes a protein:
Function:
Oxidative deamination of D-amino acids.
Sequence:
MKVLVLGAGVAGVSSAWYLAEAGHEVTVIDRAEGVAMETSFANAGQLSYGYTTPWAAPGIPTKALKWLFKSHPPLLFRPDGSLYQIEWLWQMLQNCTAAHYQTNKERMVRISEYSREMFRRFEAQTGMNFEGRKKGTLQIFRQTKEVEAAKQDIAVLERYGVPYRRLKPEECAEFEPALARVTAKIAGGLHLPADATGDCRLFTENLYKLCQEKGVRFHFNQNISRIDHNGLRIKTVETETGRFEADAVVCALGCFSRTVLAQLDLNLPIYPVKGYSLTLPVTNSDGAPVSTVLDESYKVAITRFDNRIRVGGMAELSGYEIKLPEKRRETLALVVNDLFPEGGDLSQASFWSGLRPMTPDSTPLIGRTRFDNLFLNTGHGTLGWTMSLGSAKLTADIVSGKDTEIRSDDLSLSRYQA
The following text describes a protein:
Function:
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus.
Sequence:
MEPKVVAGARSAAAASGSWWRYPSSGYLVMQSGSGNNWAQGFHGYGPQVHEDALDLVRKEVEHADSLTGFLLLQSMAGGTGAGLGTYVAEALRDEYHSAFVANCCVWPYESGEVIVQPYNTLLTLSHLADVSDGLVLLENEALHRTAAKLYGIARPSFGDMNGIAARALAAALLPSQPRGPYAGGAYVAPASQQHHHHHQAHGHGAGPGRSSPGSSGGGVQLPALRRADSSGGRLGGESPGLGSLGSRGGGATPPHAAASSPSASGAGGSGGWGVCTAPLAELVTRLCGHPAYRLLTLRSVPQLPPANIDFTTFTWPALTKRLRQMLVTGSVLEEGLDWSITPQSPGAAAALGAGLAGPTVNRALASWLILRGQGAAEADVGEFADPALSAAWSPEPLSVSYSTGRFGRCAMSACLLSNDRHCVGPIQRMQEHAYGMLESRAFVHQYEKYGLSVAEFQDCFARIEDIAQRYARL
The following text describes a protein:
Function:
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.
Sequence:
PNSAVELTLQIPATATGAAYDKCLAEVAKKVSIPGFRKGAKIPPQVIENAWSRNGGKKALKTMAINELCGELIGPALKEEYDLEPIGQPSLVTSAEVIAESFTPGEALEVTVKCDVWPDIQWKEVEGQEKPYFGLTGSYKRKPFNQERFDAALRDLKERYVKLEPYEDASQQLVMGDACVVNMVGYMATASGEKGDALPDAASGDNVEVVLGPGRYMDGLVEGLVDGKVGEVKTVNVRFPAALKNKDLAGKDAIFDVEILSASKRILPELTDEFAEQVRPGLTAESLKDELRKAVDSQDAQEYMGARNEALGKALSGVLEVEVPDTLITNQAREKYALMMTDMRNSGMADEDIKKMISPENFIKYKELSVDGIVRDFKVSMAVDEIARLENIQVPAYQVEEQMQSLKDQAAQEGQSEDMDEEQTRRKVESTLERRMVYDFLAEHANLVAE
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Sequence:
MDPIDLLRDVAKSFSTNEEIASTERVSVDITRLSLFREAKLAEARDKLQDQIRQRDLCQESVAGDSTTSERTQHVHELEREKMRLARAINDLEETLNATQAATSKLNAELELVEKESQQPIESAVENDSSAALQLKLFRTLGVTFDAEKPEKYTKCMIRSNTTSNVATLDLNVKEYSGFFITNYIWDKL
The following text describes a protein:
Function:
In complex with YALI0F03861p/CCZ1, is required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis. The MON1-CCZ1 complex acts at the fusion of vesicles with the vacuole, through its regulation of the SNARE complex during the coordinated priming and docking stages of fusion, and particularly at the stage of tethering/docking.
Subcellular Localization:
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Sequence:
MEDGAKDDYIKDIYRHASPNADTDSFLGSPTVAIDSTLSTSNSLSNLNLDTNDSSSSPPAHNDDVPDIAEVLQEMLATTELPSSTTDLDYEPELDLVGGHRRNLGQLNDYGSPRADSFVSLDPPSIGTEVEQFLSKKKQFFILSSAGKPIYTLHGSDDVILGYLGVLQTVVSAYQADESGDNLMSFRAGKTLVVVAVEGPLILAAVSKIGESESQLRAQLDVLYTQILSTLTKNQIHRIYANQSNFDLRNLLQGTDVYLDALTREIVNGSPSILLGALEPLILRKSIREEIDGVLLSCRTPSLLYGLIVSDSKLANVIRPKKHSLHPPDLILLFSMLFNTTSFRDGEHWVPICLPKFNSTGFLYAYIHFFSKSSALIQISADKNAFFELREAKQQILSQMEDKGLIKALERAEERGRFKPVDVAVPMVRHFLYKSRAHVQYVMPSYETHYYEPHMQRGLLTFYHQLHAQVNSDSSRGSNNGWRFMHLVRNSCIGFAWITPSFELYCVSGPNVSRATLAASIHSIAKWVSQHRERLFVIGGAVF
The following text describes a protein:
Function:
Receptor tyrosine kinase required for the establishment and proliferation of iridophores and their progenitors from multipotent neural crest cells. Iridophores are the blue-tinted cells that reflect light to give fish their metallic shine and which, together with yellow xanthophore and black melanophores, generate the zebrafish's stripes. Following activation by alkal ligands (alkal1, alkal2a or alkal2b) at the cell surface, transduces an extracellular signal into an intracellular response. Ligand-binding to the extracellular domain induces tyrosine kinase activation, resulting in the activation of the mitogen-activated protein kinase (MAPK) pathway (By similarity). Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MDYITRQTFVKLALFIFTVLRSSCALLEKAAEDPVHPNPLQSSPAEDSDVSFCDFESPCSWTLSSHSTGGDWFITSAQQHRSSRRDTQPIRDYSTGKSEGHFLLLKPSSSHLSAGRCSFHMTSPVVLSSGPFCHLQLARFQPEPHAGNISAFVKHTDSTDIKPIDLTIKEQESDSSQWEVLEAVIGQLNEPFQVTVQYSACSSHEVGFLAFDSLELKNCVMGDDYVDLGSDCEKYSSLQCHSGGCIEKQRVCDFHTDCPEGEDEGLICSTLPLGSYCSFELGSCGWLAADTQSSWRLVSGQQLIEDTHLLGTTLKNTQGHFLFLKVRGHGDEREALVQSPALPSTISNQDCQLQFSLYRYGDFNGTVLLSVVESGASAPALIWERSGHWKDAWQEITLPITEILNGFHLKVQAFWTSGSKADIALDDISLSAACFDTELNELLHEGLPHDLDFSPLPEPSASEASPITWWFTSCGASGPFGPTQAQCDSAYRNTNVSVVVGKEGPLRGVQMWKVPATNTYKISAYGAAGGKGAKNHNKRSHGVFISATFPLEKGDILYILIGHQGEDACPGRNPQTHKICLGESSVIEDGFDSDGSALKWAGGGGGGGGATYIYRMENGQPLPLLIAAGGGGKAYLEDPESSQDQSFREQYENDTTVSGVSGRSGAAGGGGGWSDVSSLSWAGKSLVEGGQGGSSCPEALSVLGWATFGGFGGGGGACSAGGGGGGYRGGDAPLLDDISADGQDGLSFVHPMGKIFLQPLAAMESHGEAEIVVYLNCSHCKTQSCKRDEDTKLILCLCDSDEVLAPDNVTCAGTKHSLCQFINKHLQHNSSPLVCPPLVVPMGSLADGPPSLVFIMAVIVSTVVTGVVLTCASLTLIYYRKKNHLHAVRIRLQSPEYKLSKIRSSTIMTDYNPNYGYFGKAASLSELKEVPRKNITLLRALGHGAFGEVYEGQVLGMNGENTAMQVAIKTLPEICSEQDEMDFLMEALIMSKFSHQNIVRCIGVSLQILPRFILLELMTGGDMKSFLRLNRPRTNHSSSLSMLELLHMARDIALGCRYLEENHFIHRDIAARNCLLTCPGPDRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFLEGIFTCKTDTWSFGVLLWEIFSLGYMPYPCKTNQEVLEFVTGGGRMDPPKSCPGPVYRIMTQCWQHCPEHRPNFTTILERINYCTQDPDVINTPLPVECGPPVEEEGGTVIRPDGSGSMTPLLVARSLSQDASPRASITSVTPQALKPRLQLQRPVHLTQEVGTYRETLEPCWAEPVPASGVCPGPWLQVPEHRPCSRSSSSSGSQKLKNKTKNLWNPTYGSWVLESFGRGKSALCHTQSMPLSCNPTSVSAPSSTSEHTDPVVEVNANVSASPPPSAAPSQTTLTPTAAPSRKSPTGAAGVSLATVMDLAKLQSFPCGNVNYAYDEQSYETESLPVVVSKSLEPSTSSAATSSLVALSQPGSFTHKPLVKRHASYGHEDVRRYTQPEKPTRDRDSGFSLSEDLSVTPV
The following text describes a protein:
Function:
Acts as a magnesium transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MVNTLFLPELREMLQLGQETDLREFCVTLNPGRTAEFMEGLEDAEVWAVLQYAEPYRRAEIFGYFEENRKLKMLTREPADQAAALVEEIPPDDRVDLIHALPAETVANILPLLPAIDRRDIERLRSYVEGTAGSLMTTDVAKLAERFTAREALEELGRRASDLETIYYLYVVDDNNLLRGIVSARQLVSAISNTTKTLGDLMETDVVVALVNEDQESVAGKVERFNLLAIPVVDSGRQLLGIITHDDVIDVVREELTEDAQRIAAVAPLEDDFLRIGLFKLSYKRGIWLTILFFAALLTAFALRAYEEELETFAWLVWFIPLIISAGGNSGSQSATLVITAMTGGEVKNSDLPRVLSREFVVSLLLGGFLALIGFLVALAIAPTAWAALVIPCTLLSVIFCGCMCGVTLPILFKRMGLDPALMSNPFVAGIVDILGIVIYINVARVLLG
The following text describes a protein:
Function:
Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
Sequence:
MVEVERVRYSDTLEREKIRAMIKARKEKQKEQSFENEKAVCPECGSRNLVHDYERAELVCGDCGLVIDADFVDEGPEWRAFDHDQRMKRSRVGAPMTYTIHDKGLSTMIDWRNRDSYGKSISSKNRAQLYRLRKWQRRIRVSNATERNLAFALSELDRMASALGLPRTVRETAAVVYRKAVDKNLIRGRSIEGVAAAALYAACRQCSVPRTLDEIEEVSRVSRKEIGRTYRFISRELALKLMPTSPIDYVPRFCSGLNLKGEVQSKSVEILRQASEKELTSGRGPTGVAAAAIYIASILCGERRTQREVADVAGVTEVTIRNRYKELAEELDIEIIL
The following text describes a protein:
Function:
GTPase activating protein (GAP) for RHO3 and CDC42 that binds membranes through phosphatidylinositol 4,5-bisphosphate. Plays a key role in cell polarity. Modulates the RHO3 distribution at the plasma membrane and its polarity during growth.
Miscellaneous:
MISCELLANEOUS: Present with 1720 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Bud tip. Bud neck. Note=Relocalizes from bud neck to cytoplasm upon DNA replication stress. Localizes to dynamic polarized vesicles that, while distinct from constitutive secretory vesicles, are dependent on actin and MYO2 function.
Sequence:
MSVKEHNEEDIIGDELQNSRQLSIDCDSVKISLRNTYWTKDYTTGIKLFIKHMKRENDLLIKDIKFYNDFVNKFWKPTLNNLQKMEATNSMNSRLLEVMSKQFNIISTEQVERDCKIPLQELRDLNESFLREAENDLSSRYSAYIKDLVAAKEALIGCEKRVQSIYKLKKANTPVENSSSVFDNGKDSAPLTRLNFVCEFPYTLDERLKFEDCDQFMSFLQTLKGKVILEKSVFSVPGLSNQSFQGRSLIKELKKLEPRLNLSLFNIDRIGNEFIQLGIIQEYSLSFYSSKVSQFDQEKYYYWNSEVLATQESNGNAGNRKKKSYGELTHSDNEHEEKSNVSSIKTSISDWIRKVSQHDNDDCDAAGSTDMNKNEWKSLKQQLESSQDIFFSKCCQLEYSKVQLEKTIYDYCKNYSKMEDGIKRALESSNMMFQQKCEKFTDSPVCSLQEAQLPQETANADVRGFFLRDNGIPFRRWNILEASDPVDACKEISIKSEKFFCGSEINNELAALDTLGAIKIILRQIEKEPNANKVIQSWHRDIDFVRVSNLKRDLLGEFKGSKTTENTNSIITAHFFENSHSYVTNDLVGLIKLWLLELPDSLIPSNHYDDLIKAEKSLTSLCEQFPTSSLRFLQELANHFQLINSKYSLPPQTIQDLFRDNSDIDIPLAHHFVRRTGLQNPIDIKILSPTLSTFFINERTVETLQTLIANRITTATTATLTEPPTIIIKDTTAPIHSTPKPPPNDKDGHFIPRPFKTSSTPTTPERPKRKSGLFLPINVNDVPST
The following text describes a protein:
Function:
Probable transcription factor involved in the regulation of flowering time under short day (SD) conditions. Functions as a repressor of flowering under SD conditions, independently of HD1, EHD1, MADS50 and MADS51. Controls flowering time under SD conditions by negatively regulating the expression of HD3A and FTL.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing CO3 display late flowering under short day (SD) conditions.
Subcellular Localization:
Nucleus.
Sequence:
MLKLEPEFPGLPQRCDSCRSAPCAFYCLADSAALCATCDADVHSVNPLARRHRRVPMGVVAAPGAGGAFVVRPAGGVNSSWPIREGRRCDYDDDDADAAGEEDEEATSWLLFDPLKDSSDQGLPPFGDALVADFLNLGGGAGEKEDASSSKDCSSSHGKSSEGSHEFAVPGEPVPERQGFGAVSMDITDYDASNFRRGYSFGASLGHSVSMSSLENMSTVPDCGVPDITTSYLRSSKSTIDLFTAAAGSPVAAHSIMSPPQFMGAIDREARVHRYREKRKTRRFEKTIRYASRKAYAETRPRIKGRFAKRSDTDLEVDQYFSTTADSSCGVVPTF
The following text describes a protein:
Function:
Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles. Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription. Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1. Positively regulates the assembly and activity of the mTORC1 complex.
Sequence:
MNLNSTAPMRLEIDESIIHSQLKFNNEDEEFQQLLTAAISERDNKPVDDLPYKTVKPKPGFCVKTKNVITSQKIFVNICHTAVIPSPVDVTESELTRILDSDEPSTFRIPMSLGEGHEEVDKSGQPCVAYDVAINSSFFAKVESSLLFQTFLVTIAMEGLEDKYKMELDKNGWNILKNRRCFGSIQSHRIEQRSEKPYVQEVPKTSQLKGNKSPKLIEEVDHVAVKTSTTEQLKNATPRYSLVATRDGTKIVLARIPIWQSEIGNISLSVISDDCLCVKGGEGQNIVNVNLPHSVDAQKSKAIFNKSTKILTILLPLM
The following text describes a protein:
Function:
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Sequence:
MSEDGASKCQDSIQLIDEQKQFNEKTLEYFKRCIGERDVGLDYHVISVFGSQSSGKSTLLNALFNTKFDTMNAQVKRQQTTKGIWIAHTREVQTTANTGKGVDFFVLDVEGSDGAERGEDKDFERKAALFALATSEVLIVNMWEQQVGLYQGNNMGLLKTVFEVNLSLFGHKKDKQKILLLFVVRDFTGFTPLSSLQETLTNELQAMWSELNKPAGAEGSSLDDFFDFAFTGLSHKLFKPEEFASDVAKLGDKFTDLKREDYYLSGKYHQGLPLDGWSFYADSCWEQIENNKDLDLPTQQTLVANFKTEEIANNAFEHFSTAFSKLSSSLPGPELAASMKELKDQCTKEYDNYGSRYMKAVYLEKRGELLDKIKTKFSDAIAVHMSKLFNSLVSTFQSTVAQNAACQPLSERLKVGKERVMQVFEQETSDFVALELIPSVDADASALLEKIDELAERERGKEMKAIILRAKKYQFTHTRDDIVHLLSHPQDNVWQLVMDHFDDVFRRSVLKYKLPNLGDVTDESTAYDFQLDLIEEDNYALYLKIRSNAWTILYDIIHQYLKEDNVVSILRERFESKFRYDQNDVPRLWKNEEEVDAGFKVAREHALNMLNTLSIASCDGVEIVPDVPLASDEDEAQDEQGLYNEKRFGHILTAIQKEKIIQHFKRFANVAVVEAKRSTIKSHTHIPMWIYAIIAVLGWNEFMLVLRNPLFIALMLLIVGAAYTVHRLNLWTPLATFASAAVNETTHAVKAKLRTILLDDEHPKNASSKPVESFEMQDLSVNETKENANES
The following text describes a protein:
Function:
Transcriptional repressor that regulates lateral organ polarity. Promotes lateral organ abaxial identity by repressing the adaxial regulator ASYMMETRIC LEAVES2 (AS2) in abaxial cells. Required for abaxial identity in both leaves and carpels. Functions with KAN2 in the specification of polarity of the ovule outer integument. Regulates cambium activity by repressing the auxin efflux carrier PIN1. Plays a role in lateral root formation and development.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing KAN1 develop elongated and pointed cotyledons and do not produced subsequent leaves, resulting in seedling lethality.
Subcellular Localization:
Nucleus.
Sequence:
MSMEGVFLEKTKTNTTTTLPDLSLHISLPDIHQYHHNESSKESSRRSSQLENNNRSSNFELSLSHHNHPTARIFHCPDRRTLNLPHQQHYNNPIINGVHQRVDESEISNLHRPIRGIPVYHNRSFPFHQQNSSLPSLGGGDMDQISILNSSSGYNNAYRSLQSSPRLKGVPLHHHHHHNQYGVVGSSDSSSPHHHNHHHHGMIRSRFLPKMPTKRSMRAPRMRWTSSLHARFVHAVELLGGHERATPKSVLELMDVKDLTLAHVKSHLQMYRTVKTTNKPAASSDGSGEEEMGINGNEVHHQSSTDQRAQSDDTSLHQETDISSTQPRWSNSSRETWPLSNNCSSDIDTMIRTSSTSMISHYQRSSIQNQEQRSNDQAKRCGNLSCENPSLEFTLGRPDWHEK
The following text describes a protein:
Function:
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
Sequence:
MASAIPFAARSSSGITLNVGPPVFTDLGQYGPVQSKTCKTMLFSPDGQYFAFVDGSNLKIVRTEDWNEVATIQGTKACYLSFSPKSTYLMSWEQFYVTKDDPQGKPNLNIYKSETGELVKSFVHKKQGNWEPQWSADEKLFSRISNTDVVFYEDLNFEKIVARINCHKIAAFSLSPNVGTYFILCHVPGASGQPSFGKLFKYPNFDAMQSIASKSFFQADKVEFYWNSKGNNALLLTTTEVDKTGGSYYGKQGLHFMGLNGQTAMVTMSKEGPIYSVAWSPKNHEFCVVYGFVPAKATIFNLKCEPVFEFGTGPRNALYYNPQGNLVLLGGFGNLRGHVEVWDVAARKLIGNCEAPDSTLLEWSPDGIHFLTATTSPRLRIGNGYKIWHYSGALLHEKNSGPQEELYEVCWKKFPKYAFKDPVITSEKIEGIAPSQPVASKQAYRPPSARNRPTIRFNLDDDEEQSHKPGADSQSKASLKQKKKREAKKAKKLEAGEDNKEVSAPVVSSVQINLTGDPEKDKKLKNIKKKLDAIEKLKEQQAQGKPLEINQLSKIKGEADLLKELEQLQI
The following text describes a protein:
Function:
Able to inhibit growth in several cell lines.
Subcellular Localization:
Endoplasmic reticulum. Nucleus.
Sequence:
MAAVFLVMLYEYSPLFYIAVVFTCFIVTTGLVLGWFGLEVPVILRNSEEIEFNTRVSKKEMKQVKNPFGLAITNPASASVTNGIALTPDCIEESILTCYWGCDVQELYEALQKHVYVSRISTPQALEDAIYSKYVYREQHFVKKNNKEEKYCQLPSDAKIEDFGIVPRSQYPLVALLTLADEDSQGLYDIISMVTVIHIPDKKYKLSCRILYQYVLLAQGQFHDLKQLFMSANNNTPSLSNSSPGEQSTDRHLLEKAGLAESEVEQYEENSKDCVVCQNGKVNWVLLPCRHTCLCDGCVKYFQQCPMCRQFVHEYFSLCNQKEQDKETQKSEGTVTS
The following text describes a protein:
Function:
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
Sequence:
MRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETINVNLRA
The following text describes a protein:
Function:
Involved in sporulation-specific cell division. Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity).
Subcellular Localization:
Cell septum. Note=Localizes to the divisome in sporogenic aerial hyphae in a ladder-like manner. Temporospatial localization is controlled by SsgA and it colocalizes with SsgA in presporulation foci. Localizes to the septum sites prior to FtsZ and after that colocalizes with FtsZ at the divisome throughout cell division.
Sequence:
MTIRHDSITAELALRLVVPGGAPVPVAATVRYEPADPYAISIGFRTGADEVVEWTFARQLLSDGVRRPAGDGDVQVWPAAQSGGRIVCLSLSSPSGHALFEMPRSEVLAFLRRTYSAVPLGGESDIIDLDAELALLIWGGPER
The following text describes a protein:
Function:
Required for tolerance to alcohol.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Accumulates in the nucleus specifically upon alcohol stress. Shuttles between the nucleus and the cytoplasm in a XPO1-dependent manner.
Sequence:
MEECPICLADDQEGEQFGCLNVCGHKFHLNCIREWHKYSINLKCPICRVESTHLEVGEGQHALSINLKMGFMIKNAIDYVGAETTNERNEDDTGEQDQEIEFLSERLRGTLVMDTIKIIQCSICGDTDVSRLSLYCQDCEAIYHETCLRGLACEVGDRNTWQECTDCRSNALLELRMGAISSQLASYDSRNSMIFAGELRDKHSVKTQQMYEQIRNAKHKIQMHVRRALDRYPLPLLRFKDAYKHVNKQVSRKLYRLSDNKYLPDQYDYDSLARTGVHTELLIYCHDE
The following text describes a protein:
Function:
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
Subcellular Localization:
Cytoplasm.
Sequence:
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLVAVLQGLSAWALQARELGIIDSQIDSFAPRAFFSTLTNVNFDSDRIVEYAKDAILLRHSLAVRCRLLDSTITVDHPLAELQLVADDIPSLLQQSQQFALNNDKADVGDDIHGLRMLCLYGLKGAAAYMEHAHVLGQSDEQIYAEYHAYMAWLGTQPRDVDTLLNNAMGIGKMNFNVMAILDQGETQAYGDPQPTSVNVRPVAGKAILISGHDLKDLHMLLEQTQGTGINIYTHGEMLPAHGYPELKRYPHLVGNYGSGWQNQQTEFAKFPGPILMTSNCIIDPNVGNYGDRIWTRSIVGWPGVNHLDGDNFAPVIEQALGMAGFPYSELEHLITVGFGRQTLLNAADTVIDLVASKKLRHVFLVGGCDGSRTERSYFTDFARSVPQDCIIMTLACGKYRFNKLDFGTLEGLPRLLDVGQCNDAYAAIMLAVKLSEKLGCTVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIYTGPTAPGFLTDNLMAILYEKFGMQPITTVEQDMQAILGH
The following text describes a protein:
Function:
Forms a triad with cellulose and pspB that is essential for spore outer layer formation.
Subcellular Localization:
Spore wall. Note=Depends on pspB for incorporation into the coat. Accumulates initially in vesicles distinct from prespore vesicles (PSVs).
Domain:
The N-terminal part (18-235) contains the information required for insertion into the coat.
Sequence:
MKVLLLLVCLVFAYVNASYDACYNVVCPSNYQCRAEGDQAYCVPEHHEYGCDRHSCGRGYECVERWDSFCCKPIHHRPHPHPRPPHPHPRPTNCDYTSCPREFDCHVINRNVTACLPDNHVCRDFQCPVGTHCFNGERGPHCVSDTHYPNLCRVTKCSYDFTCKMVRGNPTCLRNHDGISTHSPTHTPTHSPTTSPTHCPSCTELAPFCHSAGLVCRTILNPSCVSAVRGIINTRSCCTYIAVCASNSTSTTGATTGATTPTSTTGAATTAAATTTTATSTTGAATTAPATTTTTSTTGAATTAPATTTTSTTGAATTAPATTTTTATTIVGVTTANSVGGLTTTRATTVAGVTTANSVGGLTTAGITTVAGATTGNSVGGLTTARATTVADVTTANSVGGLTTAGVTTVAGATTGNSVGGLTTARATTVADVTTANSVGGLTTSRATTIAGATTANSIGGLTN
The following text describes a protein:
Function:
May function in a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range of substrate proteins to the endoplasmic reticulum. Involved in inorganic phosphate uptake. Also involved in telomere length regulation and maintenance (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MVSRWEKLKNNPQTKSIGISIFLMMITRVIDFSRPSLLWPLRILYATVNIVQIGIFLYTKIIIEKKNDLTVLKYVEPATPMSGREHSKFVATTVRDYDLSKLLTSFKQMLVTIATTLFMHLYMGYAPPLLLQSVSAARGLFDNSEVQIHVQNKPAIDELRRPFKSSGGLLGSFGQVLTDKKSVDEAELTKLKPT
The following text describes a protein:
Function:
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleaves pre-rRNA sequences.
Subcellular Localization:
Nucleus.
Sequence:
MVRLKSRYLLFQIVYPTDTLSTSEDAKTRFLKIHRTSDASVVNARNLTQIFKDEMEELHGDLGAGSIMTTLNVKYFSPVTSTGIVRVGRQFLREFWAALTNITDIDNTPVVINVVHVSATIKKCEIAAIERNQQIVRYLQRGGLAVKEEKVDMSDEE
The following text describes a protein:
Function:
ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
Sequence:
MKIAIIGLPNSGKTTVFNALTRGHAETAAYSSGQLEPNLATVKVPDPRLEVLAQMFKPRKITYADVQYVDIGGLSGSGRAGGGLPPVLLNYIASADALLHVVRAFDDPAVPHPNGSVDPQRDIAAVDLELAFSDLGIIERRLNRLNAEIPKLPAKEKELRTAERDLLQRLREALEAETPIRALELTEDEARLIRGYQFLTAKPMLIAPNIGEADIANPPQITYPHRQSAVEPLCGKIEAELAQLDDAEAQVFMDDLGITAPARDRVIAASYRLLGLISFLTAGPDEVRAWPIPKGTPAVEAAGTIHSDIQRGFIRAEIVAYHDLINAGSMHEAKKAGLVRMEGKQYIVQDGDICHFLFNV
The following text describes a protein:
Function:
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Subcellular Localization:
Secreted.
Sequence:
CGVQANQPAFPTGRIVGGSEAVPHSWPWAVSINLLRSKYNFWKCGGTIIHNDWIVTAAHCFANKPTTNYVVAVGRHDQNDLTSLPGDVYEIKRIVYHPDYDDPSNKFDVALLELKRSITYRREVAPACLPNPDVIPSTGGQCWLVGWGFTSNEATSPRNILKQAVQVIESPSTCQQVYKRYYYDPNTNLCSKRSESENVNMQCRGDSGGPLVCFENERWVLYGVSNFGPKTNCVYFNLYSRVGALNSFSIKRFVNE