lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Sugar-1-kinase with a very high substrate specificity for the alpha-anomeric configuration of D-galacose (D-Gal). Also efficiently converts 2-deoxy-D-Gal to 2-deoxy-D-al-1-phosphate.
Sequence:
MAKPEEVSVPIFTSLEPVYGEGSLLQEATQRFDVLKANFNDVFGASPQLFARSPGRVNLIGEHIDYEGYSVLPMAIRQDTIIAIRKCEDQKQLRIANVNDKYTMCTYPADPDQEIDLKNHKWGHYFICAYKGFHEYAKSKGVNLGSPVGLDVLVDGIVPTGSGLSSSAAFVCSATIAIMAVFGHNFEKKELAQLTCECERHIGTQSGGMDQAISIMAKTGFAELIDFNPVRATDVKLPDGGSFVIAHSLAESQKAVTAAKNYNNRVVECRLASIILGVKLGMEPKEAISKVKTLSDVEGLCVSFAGDRGSSDPLLAVKEYLKEEPYTAEEIEKILEEKLPSIVNNDPTSLAVLNAATHFKLHQRAAHVYSEARRVHGFKDTVNSNLSDEEKLKKLGDLMNESHYSCSVLYECSCPELEELVQVCKENGALGARLTGAGWGGCAVALVKEFDVTQFIPAVKEKYYKKRVEKGVVKKEDMELYLFASKPSSGAAIFNL
The following text describes a protein:
Function:
Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MGTGCRGASRCMTGTMRSLSYGSSHAQMPDREARMAEGNSDYDHRAMKLQRNLRHCEGKRLELERELFQHSSSDAHICHLKYMKLKNSLKEVCERGKKAHLRNQAFLQEFDLIEARLFGLISNANALQKKKMQLKSHPPEMNKGPNMSRSTYHPATIFMGRQMSASSSIEHCLTQRKSPQPTKSFSISDPHSVRQAAMNRNVTDSCVVPANSDIQCLNKPDKIDGNTSFQLSQKMPVTSVASSEDGRTHRAQIDKSQSGRKHLVESKQSAQLSTQILERLSPENRARDLQNDSPGNMVEKSLMYERLVPNEESFTHANPSGASPDACDYINNQTSDKHSARENLSETIESHLIPEEEDKQCLDSSSDLTVSISESEDDSYPPCEVNRIEVNQNDEKNLYTALPKQETVILKNYEQSSVIQPLQTSEVNSCDESSSASTISQSNLSDEGFFHLLQSIERMVLLREQGGMELYQRAGINQKQLLRLISVCNRMGALRVEDLEACCALVLCKTQELLKSTFVGYSHEATAGIHNTDESKERFLSRKRQERLLGHIAFLNKHHILNEKVLPECFTSVMMLSDGQNSCKSVENVENSTEDGNVPQVSSTMKDDPLTIKPRQIVQELYKTTGSSHQEFETQVHPGVVLQSANISVESNTQAEEENDEDEISDLSEIYIPGLTVEEGNATTKASKKQISETSFSSSEKSPISRKEDKNIQPNYMKSNNMSTGNKFSKVVTTVKSKAFWGESEDSSSEIEAMLRPKTESVDDFDDFFD
The following text describes a protein:
Function:
Needed for flagellar regrowth and assembly.
Subcellular Localization:
Cytoplasm.
Sequence:
MSNELPWQVWTPDDLAPPPETFVPVEADNVTLTEDTPEPELTAEQQLEQELAQLKIQAHEQGYNAGLAEGRQKGHAQGYQEGLAQGLEQGQAQAQTQQAPIHARMQQLVSEFQNTLDALDSVIASRLMQMALEAARQVIGQTPAVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVEEMLGATLSLHGWRLRGDPTLHHGGCKVSADEGDLDASVATRWQELCRLAAPGVL
The following text describes a protein:
Function:
Involved in the mitochondrial expression of subunits 6 and 8 of the F0-F1 ATP synthase.
Miscellaneous:
MISCELLANEOUS: Present with 2940 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MIINRRILKSFEEISHSLEESLREVAFDSQQQLIQDVREENEELSRLQDQLQLIRSIVEKICISIKTDNIDSYCSVPFDLLYNICKDIADPSSFEDGDLQYLVSQAIFEYIILLCYYSVTNECVQGLPAVYEAEQYYKTVSDSILKSFLYCLQNSVSTIRLLSQTVLKDVNKKKLSHQKWSLKALSVDLLEKIRPRINKFMVIRNFRFVGLPKKPIEIASLVSDIPRGIVHERLDMVTQSSKYYTIKLGQLITEFDQQPEENGMFTEVHLPNYERRLKSLQDFFGLAMSDSNLLDVIRCSAKFHKDHPLRRFTKPSILTRYWPSILLCLLYGPSSVMSLWNSRYFIQDFIKTNVVDFAKGLILNWLWAPLKQVWSTVKHDEGSAISVTSQETLNSDMDSLTRMIVSFVVDNSDSTSNSPIDPILLSTKVEHGDLTEFMEIYETQLHHPIKNIATGGLVRSLLIQLQKTKVDGSMALNGIDKMLKSQQLVFGVVALSPALVILYSSIVALKRFVKLGNVWSNEKRYREQISISLNNVERVLNYSKQGADADEEHLNQGLLVIEVSNLYKLGSFLIPRSRKKEWFRDVEELVDTNLDSGAHINVVNRIYHVYGRFLIH
The following text describes a protein:
Function:
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Subcellular Localization:
Secreted. Cell membrane.
Sequence:
MDILCSTLLLLTVPSWVLSQVTLKESGPALVKPTQTLTLTCTFSGFSLSTSGMRVSWIRQPPGKALEWLARIDWDDDKFYSTSLKTRLTISKDTSKNQVVLTMTNMDPVDTATYYCARI
The following text describes a protein:
Function:
Replicates the viral genome, host DNA polymerases cannot substitute for the viral enzyme in this process.
Subcellular Localization:
Host nucleus.
Sequence:
MKIYPYNELKTRFAEYAKPGEFNITSADTFRIIRLHYDEKQGCLFAFCNTNIKERVLQFYFKVKLNLYSYKQCYDKHIFPSCRNKCISYTTFVAPGVEGNYLNKINVIKYERNKAAPSDNAACLDKFLHNVNRVHMQTPFVEGAYMRFKKTQRCQNNYVGGSTTRMFNLQHFNEDFELVDEMTLTSGIMPVLSCYDIETHSDGHNMSKASVDCIMSIGFVVYKNDEYAKFCFMYHKLPTQIPETYDDDTYVVMFQNEIDMITAFFDMIKITNPDVILDFNGDVFDLPYILGRLNKTKMLLKRYDLPAAAPTTKLFINKLGNKVDTYYFNYYIHIDLYKFFSSDSNQHKVENFQLNTISSYYLGENKIDLPWTEMVKMYNTRRLDVIAKYNVQDCMLPIKLFVKLKMADSVYSQCILHRLCTDDVICNISHLISVACFYAAITNTRINESTGKEEPDPYFFNKNDLSIISGQFKADKAAAGISNLKRKLIPLKNIPKDAINLGPANQTVKYKGGKVLKPRAGIYKNAFSLDFNSLYLTIMIAICACLSNLILCEDGNVYLNHNSRAIVVKLLLKLLSERCKFKKNRDNQSESAFLYDLYDQKQNSVKRTANSIYGYYGIFYKVLANYITRVGRNQLRLAISLIEGLSNDPEILEKFNLGSITFKVVYGDTDSTFVLPTFNYNEISNETDTLKQICTHVETRVNNSFTDGYKMAFENLMKVLILLKKKKYCYLNSENKIVYKGWLVKKDMPVFMRIAFRTAVEQILRHLDMDKCLQSLQTSFYEYYDEFAKSKSLTDYSFSMTYNDNPGKKRKSTDDNEGPSPKRRVITVARHCREILVNKGTDFVPGNGDRIPYLLIDIEGKVTEKAYPLRLFDPVKMRISWIKHMGILCTFMNELLEIFGDEQKDKIAKCFTAIMQKYMQNQLYDRKEPVLVKINQKKCSVKRKRDDDDDNDDDDDDDCDSSDSENDTQCANNTYKFCLYKMKK
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MDISKPVGSEITSVDFGVLSDEEIRKLSAKQITNPIVFDNLGHPINGGLYDLSLGAFLRNVCTTCGLDEKFCPGHLGHIELPVPVYNPMFFNQLYIFLRSACLYCHKFKLNQLEVHNFECKLHLIQYGLLLECVELDNIMAKSSKSSSVIDVDGEDNDDEEGGGSVDEKSKKDLMKRRELFVKNAIESALKDGRTNHKGVVTASVSEERKATIHEFYKRLLSRPKCTNCGMYSPGFRKDGFTKIFENSLTDKQITNNRVKGLQRPDMIKKNAGNGNGNSSSTGAASDLPNIKHKGGSKYVLSTEVRNILRSLFHKEQAILQKVFHSRPYQHDPISGDLFFKQSVLVPPTRFRLPSKLGDEIHENAQNELLSNIIKTSVLIRDLNERITNMYKEKISGEDKKIIFNRLMNAFVTLQNDVNAFIDSTKNQNAPAGKIPNPGIKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNLETNEIGVPPVFAKKLTYPEPVTSYNASELRQAVINGPDIWPGAIQVQNEDGSLISLIGMTLEQRKAIANQLLTPNGGNSVVGKKVYRHIKNNDVVIMNRQPTLHKASMMGHKVRVLPGEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDNQYLTPTSGSPLRGLIQDHISAGVWLTNKDTFFNRETYQQLIYGCIRPEDGHTLKNRIVTVPPAIYKPEMLWTGKQVITSVLLNIKPDNVPGVNLISKNKIKSDYWSESSTENEVIFKNGELLSGILDKSQYGASQFGIVHSLHEVYGPTVAGKALSVLGRLFTNYIMMTAFTCGMDDLRLTDEGNTWRKDILKQSVDIGRVAATEVTNLDEDTKNNNKELLRRLEEILRDDNKLGILDAITQSKVNAITSQVVSKCVPDGTMKRFPYNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPFETDARAGGYIKQRFYSGIRPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSVRDADGTLIQFLYGGDAVDTTKQSHMNQFKFCVDNYDALLTKYNPGDMTENIDTDLALSYSKKVRKSLKKQKDVPHYDQVIKYDPVLNVYNPAKYLGSVSEKFQEKLDTYVSKNPTIFAQSKEETKSTGKITEKKFRALMQLKYMRSLINPGEAVGIIASQSIGEPSTQMTLNTFHFAGHGAANVTLGIPRMREIIMTASASIKTPQMTLPILADVNDEQADAFCKSVARVVMSEFVDKVVVTETTSQDVDGSNSRSYVIGLKFYTKEEYETEYDISQEQLEDVITSKFLHALEGQIVKEVKKQKKPDYMPTVGKSAGKTDMETVSGKIKEIDNDDDDEDNEVDEDHDEEQAKQNVKQQVSYEGPDDDEIETMKKAEETSDEEMDGDNSSSSDDSDSDSDNEEDADADVDMDKPSKSELSRSAKDRQSEVIASHNMVTQFNFDDELGEWCEFKLELNGNETQKLLMVNIVEDLLRKVVVREIPHIGRCIRPEPDAKTGKRILTTEGVNFRAMWDQDDFINVNGITSNDVYAVLKTYGVEAARNTIVNEIYRVFDTYGISVSSRHLDLIADMMTREGTYLAFNRQGIDSSTSAFMKMSYETTCQFLTKAVLDGDREELESPSAKIVMGKLSNVGTGSFDVFAQMPRL
The following text describes a protein:
Function:
Plays a critical role in cortical radial and GnRH neurons migration during brain development. Regulates cortical radial migration by negatively controlling the activity of histone deacetylase 6 (HDAC6) and promotes centrosome maturation. CAMDI is required for dilation formation of cortical neurons during radial migration. Plays a critical role in learning and memory performance through regulation of AMPA-selective glutamate receptors (AMPARs) cell surface expression in competition with KIBRA.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Co-localized with DISC1 at/around the centrosome. Localizes to the centrosome, at least in part, in a DISC1-dependent manner. Accumulates and oscillates at the dilation in cortical neurons during migration. CAMDI protein level is stabilized at the G1 phase and destabilized at the G2 /M phase.
Sequence:
MSCKESPHVGVSTTTVSSVAVQAGDSKIVIAVVKCGKWVRLQLAEAQPNLLEIGSSQDETRKLLHDHELLLAKLKALEDRVWGLLQEADRTAEANKEQSEVYDAMAQTLGEAWATLVSMLERRRELLGLTSEFFQSALEFAIKIDQAEDFLQNPHEFESAEALQSLLLLHDRHAKELLERSLVLLNKSQQLTDFIEKFKCDGSPVNSELIQGAQSSCLKIDSLLELLQDRRRQLDKHLQQQRQELSQVLQLCLWDQQESQVSCWFQKTIRDLQEQSLGSSLSDNKELIRKHEDLTIKAKEWDLAMEKLKSQALGILLSKDLTEKEHLQLSNQKLNRLQEEFGRLMVDRKAWLTMAHDFFTSANEAFDVLGKVEDYLKLLKSEGLSLPALAAKHEELHREIKDSTAAALQKGRTLISQVDSCRAQVTGIHETMGRIQKRVDRLSQQCTAHQEFALKKQQLATSVDDYLRKVEMSVQEMRLVLATTLDVGSSPSESEKILNKYLELDIQAKETAHALEAAAKITTEKNELELNEVALLPFKVKRLEEELSTLSRSVSYRSQVLQTYIAFRKSSEEVEEQLQSLKEFYLTESPWEDEDDAVVTCQSNSAERKWQLFLKKSFLTQDLSLEFLNLISMAKENEILNVKKEMHIVENVMEKQTNGREELSRLRMAWHLKAMEGKPVKERWETFKEKLKKTTHNVKLLHEVLMPVSALDLGGNLQSMSDLRRRWIAMQPQLQQLHEDVQQIMKEWEVLSGQGVPLKEKAEQLKDLIHLHQRQRERIQEYEEILYKTVQFHQVKEELTHLIKPRELELLAQPMELEGSKEVLMQLGRSQGRRAHVDHLHRLALSLGVDIISSVQRPNCSNISAKSLQQQLEALELDSRDWSAKAKEYEQVLACSLEYCTTREEINELKESFKDIKKKFNNLKFNYSKKNEKSRNLKTLQYQIQQVETYADKIQALRKKMEKVNKKISDSVLSYPSNKANTLVEAMEDLKKHVDDFDKVVTDYKMNLDLTEHLQEVIEECNFWYEDASATVVRVGKYSMECQTREAVDILHRQFQKFVTPSVPQQEERIQEVVSLAQRLYGLEEGQKYAEKIVTRHKEILESITELCGSLVELKEKLMQGDVPKVNSNLEDFHGNSIDLLKEPGRDEQTTFSEERSEGQAQGADVSAINGTREDGLPVGLRQSFDKEDSAQGLTLPEDTLSGEDSECISSDDISLPPLPVTPESPLAPSDMEVEEPASSSALALHISGYRMRTGTGGLGKAPESVLPPPTAFTDGYHNKKDTFTSHFERPYPQFKAEPLLTSRGSGEMSTKLHVNVKCPARMPREVHDKALPPSSQAQEISLGTQEKVHADSNVTKTQDRLHAALDVSPGLSSQSDTSRSHQRQVGPQGDRKNSSAEKSVVSLAGQAPHFSRLLSNVTVTEGSPVTLEVEVTGFPEPTLTWFKKGQKLCADGHLQVLHKDTKHSVFIPKVCEADAGLYVAQAQNSSGTLSSKAILHVTGNHGPPITRINWIVLCIIYVSVSVIYWLLTQ
The following text describes a protein:
Function:
Non-catalytic component of the KPC complex, a E3 ubiquitin-protein ligase complex that mediates polyubiquitination of target proteins, such as CDKN1B and NFKB1. The KPC complex catalyzes polyubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. The KPC complex also acts as a key regulator of the NF-kappa-B signaling by promoting maturation of the NFKB1 component of NF-kappa-B by catalyzing ubiquitination of the NFKB1 p105 precursor. Within the KPC complex, UBAC1 acts as an adapter that promotes the transfer of target proteins that have been polyubiquitinated by RNF123/KPC1 to the 26S proteasome.
Subcellular Localization:
Cytoplasm.
Sequence:
MFVQEEKIFAGKVLRLHICASDGAEWLEEATEDTSVEKLKERCLKHCAHGSLEDPKSITHHKLIHAASERVLSDARTILEENIQDQDVLLLIKKRAPSPLPKMAEVSAEEKKKQDQKAPDKEAILRATANLPSYNMDRAAVQTNMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDEAALRQLTEMGFPENRATKALQLNHMSVPQAMEWLIEHAEDPTIDTPLPGQAPSGAEGATAAAPEAAAGAGTADEEARDELTEIFKKIRRKREFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDKGIDPDSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT
The following text describes a protein:
Function:
Can act either as a transcription repressor or as a transcription activator, depending on the cell context. May be involved in neuron differentiation.
Subcellular Localization:
Nucleus speckle. Cytoplasm.
Domain:
The C2H2-type zinc finger 1 has a major repressor function.
Sequence:
MHSLDEPLDLKLSISKLRAAREKRERIGANARKRSVHHELMIRDDGTTVITPICSSPPPGFRYRDGDSPPFSSPPIVDLSLSPPSGTDSPSRSSLSPDRAAGDTLIDNPLLRCGGDSASSPFQFFLPLGSGLQLPPSMFMSPPKENRLSLEFTEQKQLVCQWAKCNRLFELLQELVDHVNDFHVKPEKDAGYCCHWEGCARRGRGFNARYKMLIHIRTHTNERPHCCPTCHKSFSRLENLKIHNRSHTGEKPYMCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCQKRYTDPSSLRKHIKAHGHFISHQQRQLLKIHQPPKLPATGDSNYTNGTQLIIPNPAAIFGSQSLPIPLTPGPLDLSSLACSSVASALAGLPNPMLTLAGSPLNLAKGSLLSQAYSAAGLGLPLISLVTSGKVENEKRPKGQRGDSSERTDGSKLRPGSIEGLSLLPRGVLDLSPGVGSESLLPGWVVIPPGSVLLKPAVVN
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MFRFAIKVGLAASAVYYLNNEGIWKESKESLKAYDKLNTTLEPYVQEARKQVPFELPQFPSGGSKVYNVQVCWNKGVTATFQFLSELPHKVNKWADEGISAILQNPDMQKVFEASGDTKDGKK
The following text describes a protein:
Function:
RNA-binding protein which forms ribonucleoprotein complexes (RNPs) that play critical roles in the localization, translational repression and turnover of RNAs during embryogenesis, neurotransmission and neurogenesis. In the oocyte, essential for the localization of both the osk/oskar mRNA to the posterior pole and bcd/bicoid RNA to the anterior pole, and is therefore required for the correct anterior-posterior patterning of the developing embryo. Association with osk or bcd at their respective poles, appears to promote the formation and stabilization of the ribonucleoprotein complexes. Integral component of diverse neuritic ribonucleoprotein complexes (RNPs) that mediate the transport, translation and turnover of neuronal RNAs during neuorgenesis and the translation repression of synaptic transcripts in preparation for their dendritic targeting.
Subcellular Localization:
Cytoplasm, Cytoplasmic ribonucleoprotein granule. Note=Detected within ribonucleoprotein granules in pherpiheral nerves that are exiting the larval central nervous system, and cell bodies within the ventral ganglion.
Domain:
Contains a proline-rich domain. The insertion of this domain in the DRBM 2 domain is required for stau-oskar mRNA localization; DRBM 3 domain binds optimally to stem-loops containing 12 bp (in vitro).
Sequence:
MQHNVHAARPAPHIRAAHHHSHSHAHMHLHPGMEQHLGPSLQQQQQPPPPPQQPPHRDLHARLNHHHLHAQQQQQQQTSSNQAGAVAAAGAAYHHGNINSNSGSNISSNSNQMQKIRQQHQHLSSSNGLLGNQPPGPPPQAFNPLAGNPAALAYNQLPPHPPHHMAAHLGSYAAPPPHYYMSQAKPAKYNHYGSNANSNSGSNNSNSNYAPKAILQNTYRNQKVVVPPVVQEVTPVPEPPVTTNNATTNSTSNSTVIASEPVTQEDTSQKPETRQEPASADDHVSTGNIDATGALSNEDTSSSGRGGKDKTPMCLVNELARYNKITHQYRLTEERGPAHCKTFTVTLMLGDEEYSADGFKIKKAQHLAASKAIEETMYKHPPPKIRRSEEGGPMRTHITPTVELNALAMKLGQRTFYLLDPTQIPPTDSIVPPEFAGGHLLTAPGPGMPQPPPPPAYALRQRLGNGFVPIPSQPMHPHFFHGPGQRPFPPKFPSRFALPPPLGAHVHHGPNGPFPSVPTPPSKITLFVGKQKFVGIGRTLQQAKHDAAARALQVLKTQAISASEEALEDSMDEGDKKSPISQVHEIGIKRNMTVHFKVLREEGPAHMKNFITACIVGSIVTEGEGNGKKVSKKRAAEKMLVELQKLPPLTPTKQTPLKRIKVKTPGKSGAAAREGSVVSGTDGPTQTGKPERRKRLNPPKDKLIDMDDADNPITKLIQLQQTRKEKEPIFELIAKNGNETARRREFVMEVSASGSTARGTGNSKKLAKRNAAQALFELLEAVQVTPTNETQSSEECSTSATMSAVTAPAVEATAEGKVPMVATPVGPMPGILILRQNKKPAKKRDQIVIVKSNVESKEEEANKEVAVAAEENSNNSANSGDSSNSSSGDSQATEAASESALNTSTGSNTSGVSSNSSNVGANTDGNNHAESKNNTESSSNSTSNTQSAGVHMKEQLLYLSKLLDFEVNFSDYPKGNHNEFLTIVTLSTHPPQICHGVGKSSEESQNDAASNALKILSKLGLNNAMK
The following text describes a protein:
Function:
Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MDWEVLYRVPMYAWTVRNIRMMYILVWSALALTVCGYNQFDDSVLFHLSWPGPELESPPPGSRIAETIEVSTADNERYRCTLPVPLSETEDSEEEYLGLSAAQLMKPIYRQVSCTYRIETYWTYELCHGKYIRQYHEEKETGKKIKLQEYYLGRFQSAEDASKQKPPPEEGKQGKTEMVPYRKLDGIDMPFFPEFMADGTPCDLKSGVPRTALILYMCHPDSKNEIVSVEEVTTCNYEIIVFTPLLCQHPDYRQKDTPVNNIHCHAISDAPVKPKTLQQVEREAQQIQTQSQRARQRSGAGSVVFKTVVQYHTHKARQRSGAGSVHYHKKQDPTGPVDPGPLKAKLPSKLPTQSSSSEQATKGFQITSLTDRQVLEEFLRGEYCLKGGTGWWKHEFCYGKHVQQYHEDQKLGNTVISIGTWNKQEHLDWAKDNPGQATPRRNRDDGKVRMVTHYYGHGDVCDVTGRPREVLVKLKCKTSDKHSVTIYLIEPNTCEYILGVESPIICSLLDTADENGLLSVPSDTVKGP
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAGSQLKQLKAALKDKGLIGQTNVSQKKSKKKNSQSSTTNNTKNINRDEKLQQLKEIRDQFNKFDQKINRSKHDISIIHQGKFVKVGSKQHNSSAIKNGNMQRQMKMQYDLEKFQHGKTGGILDKRFGENDSHLSKEEKMLARFTKERQSGSSKKRSVFSLASDDEQEPDESDGEDNGGFMLTHGGNALSLDDEETINYVDEDSLQQQPPKKKSKNEVMKEIIAKSKFYKQQRQKEFAKTQDQIDELDEDFGDVMDDLRNVQSQISKTTANSGSGKADGVFSTKTPEQIEYDNKVRELTYDRRAVPAERTKTDEEIRKEHEEKMKKLEADRLRRMEGFVDDDRDTQGDDLDNDFWAGSDRENDENEADGFTIKNSDQESDSEEEEQYQPPHKRQVKSQKITSVIMPFTIEEFIQEMSNVDPNKQPEYVKKICETYKPNLAEGNKEKMSNFVGILFEYILHIANQYQDFEPFVKILRKLAESSTSSRATTITTTTTTTTTTKAYNESLVERVREHIKHIQSRIDKQLTPGDLVFFTIIAYLFSSSDHYHIVITPSLILINQILSNIIYHPKTVTDIAHGVYLIDVLLMYQRFAKRYDPEIISFIEHALFMMIPEVDKLDTLKLLSISPTAATAGSITVQFSMNKSEKICSQEQTLSIKQLYEEDLNKSSLISKLIQLMDKCVTLWKEKSSLIEILESFISILKHITKYNATVAGPILTKFTRLHANLVKDRKPLTLQHHKAIAIATFAPKFEENFNPDKKSYDVNRERQELNKVKHELKKEKKAALKDIRQENRFIAREQISEKKRMYDDYHKKMANIVNSIQSEEGAEKNQYERERKQRKRR
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
Subcellular Localization:
Nucleus.
Sequence:
MDPTRVLSAAYPAPPAYYKNYTDENLALVKAGGTAFSTTDNLSSQLSVNLKPPNPVLEPISVFGTILDTSYKIEHIRLILINFHSLLNEYRPHQARDTLAIMMRDQIRRRKETTQSIRDEITKAQTLSADSGSDTLMSDL
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of spliced leader and U1 small nuclear RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped RNA to produce m(7)GpppNmp (cap1). Cap1 modification is linked to higher levels of translation. Recognizes a guanosine cap on RNA independent of its N(7) methylation status.
Subcellular Localization:
Nucleus.
Sequence:
MSEVTDKTVEFLLRHSASRRPPDIGSLKEKAFERVNWRDAFDRFQETERLTLWETKSELDGVDEGAYRVARDALFPFAVSGSQGAVSFGNRAGHKLREVMEATGVWEHLQRETSGQKGAVVFADVCGGPGAFSQALFEMSRQYKLRMRGFGMTLRNVRGLDWYSSLPLGKFLPTYGIDGTGDIFNLANIEALLSLTIRERLKLVVADGGFNVPFNIANYQETLSGRILFGQWLAALKLLRPGGCFILKLFDTFSPLSRALLYLSTYLYDRVHVVKPRHSRVVNSERYLVCLGFLGTPGPWMEYFEHCYQVGFSDNDSIPKIMPTSWVMEDKTFMKDLKQMNSTIASNQTLALKMVLAKLQPS
The following text describes a protein:
Function:
Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
Sequence:
MSRSRASGRPRSRRRECEFTKLGIVPDYKDVKRLQKYLTAQGKILPRRRTGVSAKMQRRLAVAIKRARHLALLPVAPSHTR
The following text describes a protein:
Function:
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex. Allophycocyanin has a maximum absorption at approximately 654 nanometers (By similarity).
Subcellular Localization:
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the core of the phycobilisome.
Sequence:
MSVVSQVILQADDQLRYPTSGELKGIQAFLTTGAQRIRIAETLAENEKKIVDQAQKQLFKKHPEYRAPGGNAYGQRQYNQCLRDYGWYLRLVTYGVLAGNKEPIETTGLIGVKEMYNSLNVPVPGMVDAVTVLKDAALGLLSAEDANETAPYFDYIIQFMS
The following text describes a protein:
Function:
Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway. Direct or indirect positive regulator of GLC7 activity.
Miscellaneous:
MISCELLANEOUS: Present with 3200 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MAEIPDETIQQFMALTNVSHNIAVQYLSEFGDLNEALNSYYASQTDDQKDRREEAHWNRQQEKALKQEAFSTNSSNKAINTEHVGGLCPKPGSSQGSNEYLKRKGSTSPEPTKGSSRSGSGNNSRFMSFSDMVRGQADDDDEDQPRNTFAGGETSGLEVTDPSDPNSLLKDLLEKARRGGQMGAENGFRDDEDHEMGANRFTGRGFRLGSTIDAADEVVEDNTSQSQRRPEKVTREITFWKEGFQVADGPLYRYDDPANSFYLSELNQGRAPLKLLDVQFGQEVEVNVYKKLDESYKAPTRKLGGFSGQGQRLGSPIPGESSPAEVPKNETPAAQEQPMPDNEPKQGDTSIQIRYANGKREVLHCNSTDTVKFLYEHVTSNANTDPSRNFTLNYAFPIKPISNDETTLKDADLLNSVVVQRWA
The following text describes a protein:
Function:
Involved in the biosynthesis of L-aspartate-beta-semialdehyde, which is an intermediate in the biosynthesis of ectoine, a highly soluble organic osmolyte, called compatible solute. Ectoine is used to avoid excessive water efflux, plasmolysis, molecular crowding of the cytoplasm, and cessation of growth in high salinity environments. Catalyzes the phosphorylation of the beta-carboxyl group of L-aspartate to yield 4-phospho-L-aspartate.
Subcellular Localization:
Cytoplasm.
Sequence:
MHTVEKIGGTSMSRFEEVLDNIFIGRREGAALYQRIFVVSAYSGMTNLLLEHKKTGEPGVYQRFADAQSEGAWREALEGVRQRMLAKNAELFSSEYELHAANQFINSRIDDASECMHSLQKLCAYGHFQLSEHLMKVREMLASLGEAHSAFNSVLALKQRGVNARLADLTGWQQEAPLPFEEMISSHFAGFDFSRELVVATGYTHCAEGLMNTFDRGYSEITFAQIAAATGAREAIIHKEFHLSSADPNLVGADKVVTIGRTNYDVADQLSNLGMEAIHPRAAKTLRRAGVELRIKNAFEPEHGGTLISQDYKSEKPCVEIIAGRKDVFGIEVFDQDMLGDIGYDMEISKLLKQLKLYVVNKDSDANSITYYASGSRKLINRAARLIEEQYPAAEVTVHNLAIVSAIGSDLKVKGILAKTVAALAEAGISIQAIHQSIRQVEMQCVVNEEDYDAAIAALHRALIEPENHGDVIAAA
The following text describes a protein:
Function:
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
Miscellaneous:
MISCELLANEOUS: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.
Sequence:
MKENLILKESEVIRILYPPGIVQTDDCYLDEEGRIYTTDTICEGTHFRIEWSGPKEIAQKLVEVNVSDIAAGGGIPTKAFLNLGLSTQCSKEEWILPFSISLQESLSSYNIELCGGDTYRSSSLNLTLTLIGVTTKPWKRSGGKDGDFLYLTGSVGLSLLGYKILKEGLDIPEPLRSLALERHLTPKARLKVSKELSKNSPVSCCMDLTDGLLLDLPKLASSSNLGLKIDLEKIPILSNILTYLSLGEVLSSGEELELIFLSPVELPKTLCETSLTKIGNTTSDWKGVKFFQGNSEKTFEHLGFEHF
The following text describes a protein:
Function:
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Also involved in sex determination and dosage compensation.
Sequence:
MKNNNNTTKSTTMSSSVLSTNETFPTTINSATKIFRYQHIMPAPSPLIPGGNQNQPAGTMPIKTRKYTPRGMALTRCSESVSSLSPGSSPAPYNVDQSQSVQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLVDDLNGGSNIGANNAVTQLQLCLDESSSHSSSSSTCSSSGHNTYYQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVGTSVPGGDAGCVSTSKNQQTCHSPTSSFNSSMSFDSGTYEGVPQQISTHLDRLDHLDNELHTHSQLQLKFEPYEHFQLDEEDCTPDDEEILDYISLWQEQ
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPSFCQECATILETMGPYDYCALCQKKYERARQGDVVTSEVHLQTHYVAQERMTENRPVIDETCPKCHHGQAYYASMQMRSADEGQTIFFECCSCGHKYRTNT
The following text describes a protein:
Function:
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MSQLSFTGKSSSKGRSRLTQEVRPTASQIIADEEASDLDEYEEDLEGSGNEDDFGPSMSRSSRGRKRRKGDPLELQSQFEERNETDAINFQLLVRNVVRYAICSQTSHNTITRKDIVQKAFPEGTSRNLFQSVFEEADRQLQLSFGFRLVAVTQSNRKKDMAVSQLRRPATSNANSSNLHRYWVLRSTLPMELQKDSRLIVDSVLDTAYYGFLMTVIAFIAVSHCSVGHSELQSFLQELLTEEETTPLHLDITRSLSLLVRQGYLDRVKDDTHNQFVYYIGSRAVTEISIEGLKSFVTEFFPDSDIDMDALLTEYRQEYQNQSSSSAA