lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Seems to be involved in the uptake of several cations and of histidinol.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDKYTNRDHPDYIPGTFNIYSSQNLENGIIYESKLKKTSSGVVLIPQPSYSPNDPLNWSSWRKLAHFGLMAFITAFTAATSNDAGAAQDSLNEIYGISYDSMNTGAGVLFLGIGWSTLFLAPFANLYGRKITYIVCTTLGLFGALWFALAKRTSDTIWSQLFVGISESCAEAQVQLSLSDIFFQHQLGSVLTVYIMCTSIGTFLGPLIAGYISAFTNFRWVGWVAVIISGGLLITIIFGCEETYFDRGQYMTPLTSCQSGYEDGTTLQNSDNTAVSRRKRHLDAKLSTPGAMGEKGVDLSETAEFEVNNEEEVTIPETRELIDGSKEHLKPYPKRVAILTKATNLKGYGFKQYFKYLKINLRMFLFPPVWLSGMFWGIQDVFLTFYLTTQESAYYEPPWNYSDFGVAIMNVPTLIGAVIGCICAGIVSDYFVLWMARHNRGILEAEFRLYFSIATAIIGPAGLLMFGIGTARQWPWQAIYVGLGFVGFAWGCSGDIAMAYLMDCYPDMVLEGMVCTAIINNTISCIFTFTCSDWLAASGTENTYIALAVINFGITAFALPMYYYGKRIRLWTKRWYLQSVNLRDGV
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MAMPGYAATASVILMMVPQSSDADTATAAHASVYKALCSVLQLQAGKIKAPDQEQEWQNAMETINDVNMTLGGPAWVNQFLKPDGTQKQWDPQTSPAKENSHWASSWAEWAASAERVFKKHGADSRPSNFSKLSITDQQLKLARTRMSLILEQASTLQTKIKSLQAAIDNAEPAKIKKLLTEAAIGTGEAAKEFTDAGKTSAARASAAFCGAGTVTGTDDCLADILICVCTQGNSDIPTGANKICSDHASNHAPKAHNLAAENDIKNQYDALVKDCNFNTEEEITPDKMLTALRSLESHIKIFKTDAYFGTTDGAATCDGTRTNGVCFKMPKYKTGKKGMQELAWATKIETAAAAMRAGATAASTSNALAASLTLLSKAAEGLASESKLFAAATTGQSSGNQPATDHLRATKEAERVCKTANDNQKECENLKDKGCVFNPKGGEGKKCTLSEEAKKKVEKENQEKWWNDGKRESNRYTRHTKKKDCEKENEGHKPGEKANCGRIEDKCNDSSFFVNKKMALSMAAAVMSLVAF
The following text describes a protein:
Function:
Required for normal synthesis of the cell wall.
Miscellaneous:
MISCELLANEOUS: Present with 2950 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Note=GPI-anchored plasma membrane protein (GPI-PMP).
Sequence:
MIVNISAKMILSICFTFLSFFKATHAMDLDTTSKTSICDATALIQGGMLDYYEGTRYGGTVGMFQSPYYWWHAGEAFGGMLENWFLCENDTYQELLYDALLAQTGSNYDYIPSNQTMVEGNDDQGIWGITVMGAVERNFTDPGDGKPGWLAMVQAVFNTMYSRWDSEHCGGGLRWQIFTWNSGYNYKNTVSNACLFQIAARLGRYTGNTTYLEVAEQVFDWLVDVGYVVLNDTANVFDGAEIDTNCTDITKIEWTYNHGIVLGGLAYMYNATNGTGEWETSLTKILNGAKSYFFKDSIMYESACQDYGTCNTDQRTFKSIFSRMLGLTSVMAPFTRDTIDDLIKTSAEAAAKSCNGGTDGHTCGLNWQKQTNDGYYGLGEQMSALEVIQNLLIHDRPAPYKEDNGGTSKGDANAGMNSSTTNVLQNNLNIKKGDRAGAAIITAVILSVLTGGAVWMLF
The following text describes a protein:
Function:
Zinc metalloprotease that mediates intramembrane proteolysis of proteins such as ATF6, ATF6B, SREBF1/SREBP1 and SREBF2/SREBP2. Catalyzes the second step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2: cleaves SREBPs within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Mature N-terminal SREBP fragments shuttle to the nucleus and activate gene transcription. Also mediates the second step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B). Involved in intramembrane proteolysis during bone formation. In astrocytes and osteoblasts, upon DNA damage and ER stress, mediates the second step of the regulated intramembrane proteolytic activation of the transcription factor CREB3L1, leading to the inhibition of cell-cycle progression.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MLRTTWIAMLLGFWSSLYLADTYLKTNRRCGEQYTSFQERCGLSVSIAHLKCYTTKFNRLFIRLGQCKPRLLRYWFTCGACFGVVLMFVAVALLLMTLVKAFSQDKPEQVLTPVMPGVNLPLNQITYFFAVLLISGIIHELGHAIAAVRENVRVNGFGVFVMLIYPGAFVDLHTEHLQALNAIGQLRIYCAGVWHNFLLVIWGVVVLMTMPYLLSPLYLTGNGVVITEVSPNSPVYGPRGLASGYQVTSINGCPVYNTETWTQCLRGVVFYPVFGHCMPAGKAQQLNKAIKMYKGSRGELECCRNDSISELCFTYRLGEGAQKPEKMYACLEARPVTELPRCHKASDCLQTRKMVCLHPSLDNSSRLLRVAHNSGPPVLYVGDPYFFSYTVRISSYVPKYDWLPLTLPEVIEMFCKYLISLSGALAILNAMPCYALDGQWILMAAVEYFLPSVITNPSDRNVIYSLIMIFGTIILIANVALAMFTLVAS
The following text describes a protein:
Function:
Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).
Sequence:
MAPLRFSANLSWLFPELPGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLINTPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEDEGYKGFVGCEYQPRGDTVEGLSWLRSYWDRRGHPEAGQ
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MDISDIARKLDLSNNKLVVRKAAEIRRLCDAQFDSSVIGVGEICKAVICLEMAASRQAAIKLSGMSEKAYTRSFNSLQNVIGVKIKLNVKELAIQFGCVRIIKSVQNMLSLYKERFLASLPASRRANADFTRPVFTAAAFYLCAKKQKLKVDKLRLVEVCGTSESEFSCVSTSMIDLCFDCVGVSKEKKDAKDVKGNRELLDVLPEKRKLEDGGYSSDDESSCYKRHKKMEEAKYEDWKTTVVHSIKKNPEKGPKKVIQTSLNFTKKAATEEVQVDS
The following text describes a protein:
Function:
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Sequence:
MFTGIVEHIGTVSEFKQLDSSQSGGNGASLTISNVGPILDDVNMGDSIAVNGVCLTVTEYDDDKTYFKAGLAPETLRRTNLGQLKSDSPVNLERAISGHVRFGGHFVQGHVDGTAEIVVKKPDGNSIAFTFKPKDQSLMTYIVEKGFIAVDGTSLTVTAVTEDTFSIMMVAYTQEKVVLAKKEVGDFVNVEVDFMGKLLEKQIDGAVEKKLGGLEALIEKIVDKKLKQ
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSSGADAYGNGAHTQYPQAEPHYSGVGGPPVDGTPLYPEAASNPVQAPRLSRFRIQGFKDVWATFVFAIFVIFSIVWSIVQLTTYHFDADPHSQSPFSGANGPRVGYVVIACLASAVASVISSIVMLALMQRIPVHMIYVANIMTIFMFLASAVLAFLRINVVVGILMIICGVFQAVWLFLVRDRIPFAAALLRTAARLISTYKLTVVLNLMLCTLSFGYITLWGYGVAAPVDRMYKDQANGGYMFVVAVLVFSMLWMSQVTPNVMHVTTSGLVATWYFAGSDNMPRNPTLASFKRATTTSFGSICFGSLVVAIIQFIRWLVESAGSDYENGFLHCLLACILQCIERIVEYFNRYAFVHVAIYGCSYIEGAKRTFTLCKQCFFAAYFNDCLVSPTLNMFTLAVSLVFALIAGVSSKSWPIGVLVFVVAVLVHSLFFVPVDSAVTTVFVCFAECPEALRESDLQLYATIHAADANGTHNNAPPPL
The following text describes a protein:
Function:
Transcription factor that regulates asexual reproduction. Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes. Required from the very earliest events of asexual reproduction until completion of conidiophore development, but is not specifically required for differentiation of conidia. Represses transcription of the abaA developmental regulatory gene and of the developmentally regulated awh11 gene. Controls the expression of the catalase-peroxidase gene cpeA. Plays an important role in cell wall biogenesis during the development by controlling the transcription level of fksA.
Subcellular Localization:
Nucleus.
Sequence:
MASMNQPQPYMDVHSHLSSGQTYASHPATAGALTHYQYPQQPPVLQPTSTYGPASSYSQYPYPNSVASSQSVPPPTTSISSQVPAQLLPLPVTNHPVPTHGYGNNSGTPMQGYVYDPTGQMAPPGAKPRVTATLWEDEGSLCYQVEAKGVCVARREDNGMINGTKLLNVAGMTRGRRDGILKSEKVRNVVKIGPMHLKGVWIPFDRALEFANKEKITDLLYPLFVQHISNLLYHPANQNQRNMTVPDSRRLEGPQPVVRTPQAQQPPSLHHHSLQTPVPSHMSQPGGRPSLDRAHTFPTPPASASSLIGITSQNNSYDWNPGMNSSVPNTQPLSIDTSLSNARSMPTTPATTPPGNNLQGMQSYQPQSGYDSKPYYSAAPSTHPQYAPQQPLPQQSMAQYGHSMPTSSYRDMAPPSSQRGSVTEIESDVKTERYGQGTVAKTEPEQEQEYAQPDSGYNTGRGSYYTTNPSVGGLAHDHSQLTPDMTGSPQQNGSGRMTPRTSNTAPQWAPGYTTPPRPAAASSLYNIVSDTRGTSGANGSTSDNYSVASNSGYSTGMNGSMGSNKRMRDDDDDRIVPPDSRGEFDTKRRKTLTETPVGGPVGGVPLGLQPMKAGGSLISARR
The following text describes a protein:
Function:
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins (Probable). Has an essential role in mediating growth by negatively regulating insulin signaling. It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae.
Miscellaneous:
MISCELLANEOUS: The name 'Ohgata' means 'large' in Japanese and refers to the overgrowth phenotype in mutants.
Subcellular Localization:
Nucleus.
Sequence:
MDEEENSEINSVQARDEDVQLEDQQSQGLQDRQVDVIEQAWNNAMPDEPSPPAEDAFQDPLATDGEGGDALEAMVENVLQDDTASEGSHPSSDMSLESPGSEDDSDLESLPHWMIPQNRLRSAVDMMVSQARNRDGGIAALLSGDNFLQRVRSMVFSQERRRSRTSEETSQEAAEQPVDPPPQQPPRPPIDIGFDTNLPAEHSYFGNHLSRVPGVDYLEVGSVHHMLIFLHQHILFPGEVLPFMIDGRMFDEDMPGLDGLIFGVSFPRLQPPEDNPHKLYGVTCQIYERGESGRGLVFYKSRALQRIVINCDDIKGSPQYIARNPTSKCFSKVKILPEYFLPEPLQTVDMGSMARFRDIPSMRDKYRRFQLSTTTWPSDACQEYSFSSIVERARQRLESQKIDTMPKCPIQLSFWLVRNLHLTEKMMRLTFLTDSVNTRLQLIKSTFKDETLFFCRYCNSSLALCSDLFAMSKHGVQTQYCNPEGYIHETNTVYRVISHAIGYSGEPSTKFSWFPGYQWHIILCKFCAQHVGWEFKAVHPNLTPKVFFGLAGSSVRIGKASEYSPFNGTTYVVRNMMRMISSDME
The following text describes a protein:
Function:
Functions as a receptor binding protein (RBP) and mediates the attachment to the host capsular exopolysaccharides (By similarity). Displays a lyase activity that specifically degrades the K1-type polysaccharides of Klebsiella pneumoniae capsule.
Subcellular Localization:
Virion. Note=Tail appendage.
Sequence:
MALIRLVAPGRVFSDLASMVAYPNFQVQDKITLLGSAGGDFTFTTTASVVDNGTVFAVPGGYLLRKFVGPAYSSWFSNWTGIVTFMSAPNRHLVVDTVLQATSVLNIKSNSTLEFTDTGRILPDAAVARQVLNIIGSAPSVFVPLAADAAAGSKVITVAAGALSAVKGTYLYLRSNGLCDGGPNTYGVKISQIRKVVGVSTSGGVTSIRLDKALHYNYYLSDAAEVGIPTMVENVTLVSPYINEFGYDDLNRFFTIGISANFAADLHIQDGVIIGNKRPGASDIEGRSAIKFNNCVDSTVKGTCFYNIGWYGVEVLGCSEDTEVHDIHAMDVRHAISLNWQSTADGDKWGEPIEFLGVNCEAYNTTQAGFDTHDIGKRVKFVRCVSYDSADDGFQARTNGVEYLNCRAYRAAMDGFASNTGVAFPIYRECLAYDNVRSGFNCSYGGGYVYDCEAHGSQDGVRINGGRVKGGRYTRNSRSHIFVTKDVAETAQTSLEIDGVRMRYDGTGRAAYFHGTMGIDPTLVSMSNNDMTGHGLFWALLSGYTVQPTPPRMSRNLLDDTGIRGVATLVAGKATVNARVRGNFGSVANSFKWVSEVKLTRLTFPSSAGALTVTSVAQNQDVPTPNPDLNSFVIRSSNTADVSQVAWEVYL
The following text describes a protein:
Function:
A cytochrome P450 monooxygenase involved in primary bile acid biosynthesis. Catalyzes the 12alpha-hydroxylation of 7alpha-hydroxy-4-cholesten-3-one, an intermediate metabolite in cholic acid biosynthesis (By similarity). Controls biliary balance of cholic acid and chenodeoxycholic acid, ultimately regulating the intestinal absorption of dietary lipids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH--hemoprotein reductase) (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Sequence:
MTLWCTVLGALLTVVGCLCLSLLLRHRRPWEPPLDKGFVPWLGHSMAFRKNMFEFLKGMRAKHGDVFTVQLGGQYFTFVMDPLSFGPIIKNTEKALDFQSYAKELVLKVFGYQSVDGDHRMIHLASTKHLMGQGLEELNQAMLDSLSLVMLGPKGSSLGASSWCEDGLFHFCYRILFKAGFLSLFGYTKDKQQDLDEADELFRKFRRFDFLFPRFVYSLLGPREWVEVSQLQRLFHQRLSVEQNLEKDGISCWLGYMLQFLREQGIASSMQDKFNFMMLWASQGNTGPTCFWVLLFLLKHQDAMKAVREEATRVMGKARLEAKKSFTFTPSALKHTPVLDSVMEESLRLCATPTLLRVVQEDYVLKMASGQEYQIRRGDKVALFPYLSVHMDPDIHPEPTAFKYDRFLNPDGTRKVDFYKSGKKIHHYSMPWGSGVSKCPGRFFALSEMKTFVLLMIMYFDFKLVDPDIPVPPIDPRRWGFGTSQPSHEVRFLYRLKPVQ
The following text describes a protein:
Function:
May regulate the kinase DMPK.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGSRAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIVEP
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MASGSSSSNDAAADLTVLVDDFYFSVLSHGRNDDDDSADGDDGELFPISDEKYASELQLQEVIMSSSVAATTARSSSAPVIFIGECSSSHAASSSSRLTSIPAAAATTLVFCKICMDAVPPSAAHRASRGCDHAFCAACLAGYVGAKIQERIADVRCPEERCRGALDPELCQGILPREVFDRWGAALCEAMVLAAPRAYCPFKDCSAMMLDDAGEAVTESECPSCRRLFCAQCAVPWHAGVDCAAYKKLGKGDRGKEDLLVVEMAKGKKWKRCPKCKYFVEKSQGCLHITCRCGFEFCYGCGGQWGVTHASCSTA
The following text describes a protein:
Function:
Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTTRKHNEFLDIGTSDDEDNDAGYDSEAAEESKGRTVKRRKTQSREDGIESASEDESSGGSEGEESDTEAGGVRLREKKRGQRDEYENDSDDDGNYMNQESQYLDVTAEVEKAKAKKNQKPLDKLKNKPPKKNKTGVVYFSSLPPYLKPFALKSLLETRGFKPITKVFLTPAVRPPSAPRRRSNKRKTYTDGWVEFASKKTAKICAETLNATIVGGKKGGWYHDDVWNMKYLKGFKWADLMETQERERSEREAKRRIEDARARKEEKVFLQGYEKGKMLEGIQKKNEEKRRKKMADKDGHGDQGKEQAINARRLFKQNEVKLGRDKTSADQTTVEEDTRRVLGKIF
The following text describes a protein:
Function:
Pore-forming subunit of the rod cyclic nucleotide-gated channel. Mediates rod photoresponses at dim light converting transient changes in intracellular cGMP levels into electrical signals. In the dark, cGMP levels are high and keep the channel open enabling a steady inward current carried by Na(+) and Ca(2+) ions that leads to membrane depolarization and neurotransmitter release from synaptic terminals. Upon photon absorption cGMP levels decline leading to channel closure and membrane hyperpolarization that ultimately slows neurotransmitter release and signals the presence of light, the end point of the phototransduction cascade. Conducts cGMP- and cAMP-gated ion currents, with permeability for monovalent and divalent cations. The selectivity for Ca(2+) over Na(+) increases with cGMP concentrations, whereas the selectivity among monovalent ions is independent of the cGMP levels; [Isoform 2]: Pore-forming subunit of the olfactory cyclic nucleotide-gated channel. Operates in the cilia of olfactory sensory neurons where chemical stimulation of the odorant is converted to an electrical signal. Mediates odorant-induced cAMP-dependent Ca(2+) influx triggering neuron depolarization. The rise of intracellular Ca(2+) levels potentiates the olfactory response by activating Ca(2+)-dependent Cl(-) channels, but it also serves as a negative feedback signal to desensitize the channel for rapid adaptation to odorants.
Subcellular Localization:
[Isoform 2]: Cell projection, cilium membrane; Multi-pass membrane protein.
Sequence:
MLGWVQRVLPQPPGTPQKTEEGAGPQPETESKPEANPQPEPEVQPEPEPEPEPAPEEAAPEVQTLPPEEPVEGEDVAEAGPSLQETQEADPPQPTSQAQVAVVKVNRPSSWMLSWFWKGMEKVVPQPVYSSSGGQNLAAGEGGPDQDGAQTLEPCGTGDPGSEDGSDKTSKTQDTEPSLWLLRWLELNLEKVLPQPPTPSQAWKVEPEGAVLEPDPPGTPMEVEPTENPSQPNPGPVEPEEEPAAEPQPGFQASSLPPPGDPVRLIEWLLHRLEMALPQPVLHGKAAEQEPSCPGTCDVQTISILPVEQAEHDLVLEDVDSCWEDTQQEDGASLQETELAPIYEDESEAMVEMPRELPQIQEEEEEEKEEKEEKEEEEEKEEEEKREEEKKKEKEEEKKEKEKEEKEEKEEKEEEEKEEKEEEEKEEKEEEEKEEKEEEEEEEEEEEEEEPIVLLDSCLVVQADVDQCQLERAQPETASIQELPEEEEEKEEEKKEEEEEKEEEEEKEEEEEKEEEGEATNSTVPATKEHPELQVEDTDAEAGPLIPEETIPPPERPPVSPAKSDTLAVPGAATHRKKLPSQDDEAEELKALSPAESPVVAWSDPTTPQEADGEDRAASTASQNSAIINDRLQELVKMFKERTEKVKEKLIDPDVTSDEESPKPSPAKKAPDSAPAQKPAEAEAAEEEHYCDMLCCKFKRRPWKMYQFPQSIDPLTNLMYILWLFFVVLAWNWNCWLIPVRWAFPYQRADNIHLWLLMDYLCDFIYLLDITVFQMRLQFVKGGDIITDKKEMRNNYLKSQRFKMDLLCLLPLDFLYLKLGVNPLLRLPRCLKYMAFFEFNNRLEAILSKAYVYRVIRTTAYLLYSLHLNSCLYYWASAFQGIGSTHWVYDGVGNSYIRCYYWAVKTLITIGGLPDPQTLFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPRSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDGKAVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPESQKLLRKKARRMLRNNNKPKEEKSVLILPPRAGTPKLFNAALAAAGKMGPRGAKGGKLAHLRARLKELAALEAAARQQQLLEQAKSSQEAGGEEGSGATDQPAPQEPSEPKEPPEPPAPSSPPPASAKPEGSTEEAAGPPEPSVRIRVSPGPDPGEQTLSVEMLEEKKEEVE
The following text describes a protein:
Function:
Required for multicellular development and for both mechanisms of gliding: social (S) and adventurous (A) motility. Acts as an intracellular switch to coordinate A and S motilities. Controls the direction of gliding and gliding speed.
Subcellular Localization:
Cytoplasm.
Sequence:
MSFINYSSREINCKIVYYGPGLCGKTTNLQYIYNKTAAETKGKLISLSTETDRTLFFDFLPLSLGEIRGFKTRFHLYTVPGQVFYDASRKLILKGVDGVVFVADSQIERMEANMESLENLRINLAEQGYDLNKIPYVIQYNKRDLPNAVTVEEMRKALNHRNIPEYQAVAPTGVGVFDTLKAVAKLVLTELKKGG
The following text describes a protein:
Function:
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of the anamorsin/DRE2 homolog, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MKGMRKLLILYASQTGNALDAAERLSREAERRACPFNLLSVDQYDPSLLPQEEAVIFVVSTTGQGDTPDSMKVFWRYLLQRNLGQRWLSGVLYAVFGLGDSSYQKYNFVAKKLDKRLMDLGGTTIVERGLGDDQHPSGYEASLDPWLSSLWRMLNMVKPEFLPNGPDVVIQDTVLIDQPKVRITYHNIANDESHFSSASDLTCLNMQIGSARSMHPGKSSSDRSRPGCFLKMVKNLPLTRSNCGKDVRHFEFEFVSHVLKYETGDVLEVLPGQDSAAVDAFIRRCNLDPDSFITVSLREMDDHNTHDSRIPVKLRTFVEFSMDVASASPRRYLFEVMSFFATAEHERERLKYFASPEGRDDLYQYNQKERRTVLEVLEDFPSVQMPFEWLVQLVPPLKPRAFSISSSQSAHPNQVHLTVNVVSWTTPYKRKKKGLCSSWLAALDPCDGIHVPTWFHKGLLPTPSPSLPLILVGPGTGCAPFRGFIEERAVQSRTNSTAPIIFFFGCWNEDGDFLYRDFWLSHSQNKGVLSEAKGGGFYVAFSRDQPQKVYVQHKMREQSQRIWNLLAEGAAVYIAGSSTKMPADVTSAFEEIVSYENEVSAEDAVRWIRALEKCGKFHIEAWS
The following text describes a protein:
Function:
Thiol protease which is required for parasite excystation and invasion of the proximal small intestine of the human host.
Subcellular Localization:
Vacuole.
Sequence:
MFNLEEKIQGSKLLKELKGEKDLPWVAGENERFKGMTFKDASVISGNAHKLRPDTIPLARPPKINISIPMSYNFTERFPQCDFGVLDQGKCGSCWSFAVSKSFSHRYCRKYNKPVLFSQSHLVACDRRNSGCGGGIEVNAWRYIDLRGLPLDSCQPYDGNITKYNCSKKCTNESETYEAQFTEYWSVARYASIEEMQIGIMTEGPVTTSLKVYSDLMYYKSGIYTHTKGEFLGHHAVEIIGWGTKNGIDYWIISNSWNTTWGMNGLFLIKRGVNECHIEDYVCAGKVK
The following text describes a protein:
Function:
Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3 (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MAGSATIVAGLLLLVACACCIFPIDSVTIPSSCCTSFISKKIPENRVVSYQLANGSICPKAGVIFITKKGHKICTDPKLLWVQRHIQKLDAKKNQPSKGAKAVRTKFAVQRRRGNSTEV
The following text describes a protein:
Function:
Cell wall peptidoglycan (PG) DD-endopeptidase. Hydrolyzes peptide cross-links which covalently connect adjacent PG strands probably to allow insertion of new glycans and thus cell wall expansion. Degrades purified whole PG sacculi in vitro.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=Localizes to the periphery of the cell and at the midcell in a subset of cells.
Sequence:
MLSLFNRLPWLHRVLITAFSAIIVFAIFFLPNSEDLRKPDAQREVGRHYPVTLDNQLVSTPEEEVIAPPSVMLRWETYQVANGESAALLFQRAGLSSRVLYELTSSNSDINNQLSKLMPKDELKFGFDKDNQLVQLKRTISPYETFVVTRSDSGFTSEFDKKEVTFQLNYAEAKITSNFWNAGVTAGLSANQIIELANMFGWDIDFALDIREGDQFKLLYQEKIVEGSVIGRGNIIAATFINQGSTFTAILDDNTGNYYDQNGRAMKKAFLRSPLDFRRVSSNFNPRRLHPVTGQIKAHRGTDYVAPVGTPIWAAGDGVVEKSSYNQFNGNYVYIRHSNTYITKYLHLQRRLVKTGERVKQGQTIGTLGGTGRVTGPHLHYEFLVNGIHKNPRTVELPQAQSLTGKAKETFIANAKQRMEKLERYSQLLYANQ
The following text describes a protein:
Function:
Contributes to invasiveness in malignant prostate cancer.
Subcellular Localization:
Cytoplasm, perinuclear region. Nucleus.
Sequence:
METGVTPKGSSTVQLGLGENPLDPSSQHRLEGEKEVIRKAIQKELKIKEGAENLRRVTTARRNLGHVDQLLRSSNRRLEQLHWDLQELNARILLPDETHSPAASEPHLREEKPVAKHLEALRKQLQIELKVKQGAENMTNTYANGSPKERRLLSAAQQMLRDSKVKIELLRMQIGKLGASGETLEPGPEQRRELRAGDLRHRFRIETAVAEGAKNVVKLLGGRRLQDRKALAEAQTRLRESLQKLDLLRLALERLMTELPPAHPLRILVARELREGMPRSPQPTGSLIKPIALTGTLEVRLTGCQELLEVVPGRSRVAALMGSPGESRPWGWGKQQRVEELTKEVLAVLKVDNHMVGQTGWGPVSAQAWDQTFLIPLERSRELEIGVQWRDWRELCGVAFLRLEDFLDNARHTLSLGLEPQGQLFVEVMFCDPVIERRPRLQRQKRIFSKHRGQDFLRASQMNISMAAWGRLVMSLLPPCSSSTLSPPGRPSSTSPHDSPGSLSPSSFPLTKPLVEETTPRKALVGEQLPPKPPRLHLPLDSAFVESPCTKRPHMDYRNSLRQGPCATPIRKPPKFQDFCCIAVLGRGHFGKVLLAQYKKTGTFYAIKALKKQEVLSRDELESLYCEKRILEMVGHSGHPFLLSLLVCFQTPSHFCFVTEFVPGGDLMMRIHADVFPEPQARFYLACVVLGLQFLHEKKIVYRDLKLDNLLLDANGFLKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDESYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNEEAPYPHFLSVEGLALIQKLLQKCPEKRLGAGRRDAEEIKVHPFFRSTDWEALLSCRIQPPYVPMLRGPADLRHFDQEFTALPPALTPPDRHCPLTARQQAAFLGFDFVSDQFLEA
The following text describes a protein:
Function:
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MSLLRLSTRKAFASLPRNCNASSFSLSLLNRNHTFGNNRITSCLSAAAFHTSPLALASPSTKPASNAEAFLNGPSSAYIQEMYAAWLQDPKSVHLSWQSYFKNLASNGQAPAFSAPPTLIPSFSTQVMGADGAPSLHESGSDNGAIPADSILDHMKVQLLVRAFQVRGHQLANIDPLEINSFRDRVQAPELDYTYYGFTEKDLDESFYLGSGILPGFLATEGQTNLTLREIVDRLKQTYCSTVGIEYGHIPDRIACDWLRKKFEVPSKFNYTKEEKLTILDRLMWSDSFERFVSTKYPSEKRFGLEGCESLIPGMKAMIDTSVELGINSVVMGMPHRGRLNVLSNVVRKPNESIFSEFAGSQANSVEGSGDVKYHLGMNYVRPTPSGKIVHLSLAANPSHLEAVNPVVEGKVRGIQFYQNDEVERSKAMAVLLHGDAAFAAQGVVYETLGMVDLPAYTTGGTIHIVVNNQVGFTTDPRFARSTPYCSDVAKTVNAPIIHVNGDDVEAVVFACQLASEWRAEFKKDVVLDIVCYRRYGHNEIDQPGFTQPLMYQKINQMTPVLEKYIQQLLGEGSVTQEEVDAMKKRVWGILEEHYILSKDYKASSKEWVSSTWSGFRSPSVLAKEAVSPRPTGVSLDLLKHIGTAGATYPADFKVHPNLARILKTRIKSVTEGQDIDWATAESMAFGTLLCEGNHVRLSGQDVERGTFSHRHALLHDQKSEKQFVPLNNLVSEGIVSSQSPFTVCNSSLSEFGTLGFELGFSLVNPDQLVMWEAQFGDFANNAQCIIDQFIASGEQKWLQRTGLTMLLPHGYDGQGPEHSSARLERFLMLCDEDPYCMPELNGTEKGSRSRQHQDCNMQVVYTTVPSNYYHALRRQVHREFRKPLIVFTSKAVLRHPLAKSCIEEMVGNTRFQRLIPEVLHPNPLTILSPNGASEPNADGSLSSGNSFDPRIPYALVTDPAYPPALQDGTTKAVTPSGFTLLPPNEIKTLIFCSGQVYYSLYRTRALNNLRHVAIVRIEQLNPFPFWEVKTIVDFYKEGLEEIVYCQEESFNSGAWLFVDPRLETAVKNSDWFKGPKDDTLPVSSVSTPLSTSTIEPPECAPQSTSLFGRFFGSSSASKPTSTRVSPSPTYSTKSINTKTKGQQWQETFDSKRVPGGLENAHTTPEGQKAYSVRGSRLIRYAGRDISAAPATGIKKQHKFEEKAFLSEAFLGGELVYPPKSIEQDLPVFF
The following text describes a protein:
Function:
Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNKANLLYTDTNMKTFLFSEVSVGISANSMLFIVHICILLGENRPKPINLYIAFLSLTQLMLLITMGLIVADMFMSQGIWDSITCQSLIYLHRLLRGLTLCATCLLNVLWTITLSPRSSCLTKFKHKSPHHISGAFLFFCALYMSFSSHLFLSIIATPNLTSEDFMYVTQSCSLLSMSYSRTSMFSTAIAIREAFLISLFALCSGYMVALLWRHKKQAWDLHSTNVSSKSSPEQRATRTIMLLMSFFVVLYVLENAVFHSRMKFKDGSMLYCVQIIVSHSYATVSPFVLICTEKRMIKFWGSMFGRIVNI
The following text describes a protein:
Function:
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
Subcellular Localization:
Cell outer membrane.
Sequence:
MRNALYALLFNLYRLFCWSLVLMGMLPIAHAATPPDWSKGAYAYSAEQTPLSAVLQDFANSHGVDLVLGNIQDINVEAKIRADNAVAFLDRLALEHRFQWFVYNNVLYVSPQDEQTSVRIEVSQDAAPDMKQALTGIGLLDSRFGWGELPEEGVVLVTGPAEYVNLIRNFSQQRETKEDRRKVMIFPLRYASVSDRTIQYRDQRLVIPGVATILNELMDGNRNTPAGASAAASGMGNDGAMAAASGGGQDASQAIELNARAMLARLATRSSGGATAAARKKDQLNGKVSADVRNNALLIRDDEKRRDEYQQLIDKIDVPQNLVNIDAIILDVDRTALSRLEANWQGKLGAVTGGANMMSGSSTLFVSDFKRFFADIQALEGEGTASIVANPSVLTLENQPAVIDFSRTAFITATGERVANVQPVTAGTSLQVTPRVVGRGSLSSIQLVIDIEDGQVETNTEGTASGVKRGTVSTQALIGENRALVLGGFHVEESGDRDKRVPLLGDIPWIGKLFTSRQHEVSRRERLFILTPHLIGDQNDPTRFVSADNRRQLNDAMGRVAQRNSKTDLFSVVESAMRELASGQTPAGFTIDGSGARLSEFCRTSPSLSYQSNRHQWYSNLTLSLAVGVVKNIGTRPQRFDEANCASSRTLAVAAWPKTTLAPGESTEVYLALLPAKNAQPSRASLIKP
The following text describes a protein:
Function:
Probably involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSSQARDNLILAKKRLVQVLGDNEKAYWSNMKAWFKHGLTKEEFDVESRRLLPKDGAHLHNMFLLAVLTKCHVSSSSSSKDTTSTVAANKIKKNRRIQSLKRKFDHRFTPHTPVPSPTPPGPHKPAPKPTQQPIRTCIRTYEVPSIEEMVGYTSVIAWEAGLDEATDGAVEFATEAVRVFLKNILSAIFTRRSAYKLFRKARYSMGCEPTNPYLHNRSSPNDKSLLSYEEKEQQRIEEIGKTSQIAVDPKGPVNLYDLLYTLKTYRLSLIPSNTVYSSAVERVVSHMWHPSHDEVECQQKFTTLMKS