lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA.
Subcellular Localization:
Chromosome, telomere. Nucleus inner membrane. Note=Localizes to telomeres throughout meiotic prophase I and disappears in metaphase I. In leptotene spermatocytes, localizes to telomeres that localize to the nucleus inner membrane.
Sequence:
MFQGQRGWFCGSVSQDLRQFWVAEGGTISDPRAADFLFSCDASHPDTLRIYQSLDYIEDNATVFHAYYLSAVANAKIKNSVALGHFILPPACLQKEIRRKIGSFIWEQDQHFLIEKHDEVTPNEIKTLRENSELATEHKKELSKSPEKHFIRTPVVEKQMYFPLQNYPVNNMVTGYISIDAMKKFLGELHDFIPGTSGYLAYHVQNEINMSAIKNKLKRK
The following text describes a protein:
Function:
Part of the plasmid amplification system, which corrects any decrease in copy number caused by a rare missegregation event. Catalyzes the recombination between the large inverted repetitions of the 2-micron plasmid during plasmid replication. This recombination event changes the direction of one of the two replication forks in the bidirectionally replicating molecule, effectively resulting in multiple rounds of replication from a single initiation event. Binds specifically to the FLP recognition target (FRT) site where it induces DNA to bend. Three types of bend exist. Type I is approximately 60 degrees and results from 1 FLP molecule binding to 1 symmetry element. Type II is >144 degrees and results from FLP molecules binding to symmetry elements a and b. Type III is approximately 65 degrees and results from FLP molecules binding to symmetry elements b and c.
Miscellaneous:
MISCELLANEOUS: The plasmid 2-micron circle is a extrachromosomal element that resides in the nucleus and propagates itself stably in host cell populations. It provides no obvious advantage to the host but imposes no significant disadvantage either at its steady-state copy number of 40-60 molecules/cell.
Sequence:
MPQFGILCKTPPKVLVRQFVERFERPSGEKIALCAAELTYLCWMITHNGTAIKRATFMSYNTIISNSLSFDIVNKSLQFKYKTQKATILEASLKKLIPAWEFTIIPYYGQKHQSDITDIVSSLQLQFESSEEADKGNSHSKKMLKALLSEGESIWEITEKILNSFEYTSRFTKTKTLYQFLFLATFINCGRFSDIKNVDPKSFKLVQNKYLGVIIQCLVTETKTSVSRHIYFFSARGRIDPLVYLDEFLRNSEPVLKRVNRTGNSSSNKQEYQLLKDNLVRSYNKALKKNAPYSIFAIKNGPKSHIGRHLMTSFLSMKGLTELTNVVGNWSDKRASAVARTTYTHQITAIPDHYFALVSRYYAYDPISKEMIALKDETNPIEEWQHIEQLKGSAEGSIRYPAWNGIISQEVLDYLSSYINRRI
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MISFREENIDLNLIKTISVICNDPDATDSSSDDESISGNNPRRQIKPKPPKRYVSKICVPTLIKRYENVSNSTGNKAAGNRKTSSGFKGVRRRPWGKFAAEIRNPFEKKRKWLGTFPTEEEAAEAYQKSKREFDERLGLVKQEKDLVDLTKPCGVRKPEEKEVTEKSNCKKVNKRIVTDQKPFGCGYNADHEEEGVISKMLEDPLMTSSIADIFGDSAVEANDIWVDYNSVEFISIVDDFKFDFVENDRVGKEKTFGFKIGDHTKVNQHAKIVSTNGDLFVDDLLDFDPLIDDFKLEDFPMDDLGLLGDPEDDDFSWFNGTTDWIDKFL
The following text describes a protein:
Function:
ABC-type transporter; part of the gene cluster that mediates the biosynthesis of cichorine, a phytotoxin active against knapweed, corn, and soybeans. CicA is probably involved in the secretion of cichorine (Probable).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRLSSEAKIAESGGQPPTAGSRSETGSESTEAESADPKAQKWYQRSLNPLRWQKIPPVPEERTVSREYGASFFSIASFQWMAPLMKVGYLRPLELQDIWTVNPDREVDVLTKRFEVSLEKRTNAGAKRPLLWALYDTFRFEFLLGGFCHLISSLLIVFAPYLTRYQIAFATEAYVAQRSGQPAPRIGRGMGFVVGITVMQAIQSLCTNQFLYRGQMVGGQIRAVLILQIFNKAMKLSGRAKAGGVQSPEQQEKIKELKAAKDQALKKPGSPPADDKGWGNGRIVALMSIDVDRINLACGMFHISWTAPVSIIVALILLLVNLTYSALAGFGLLVIGMPFLTYAVRFLFKRRRNINKLTDQRVSLTQEILQGVRFVKFFGWESSFLDRLKEIRHHEIRSIQTLLAVRNGILCVSMAIPVFASMLSFITYALSNHVLDPAPIFSSLALFNSLRMPLNLLPLVLGQITDAWTALNRIQEFIVAEEQKEDIERDEHMPEAVRMDRASFTWERKAADKEAEKVEKKANPRRTEPKSEAPTDSAESDEPFQLRDMTLDIRRDELVAVIGTVGSGKSSLLAALAGDMRLTDGSVRLSTSRAFCPQYTWIQNTSLRDNILFGKDYDEKWYDQVIDACALKPDLEILPNGDATEIGERGITISGGQKQRLNIARAIYFNAELVLLDDPLSAVDAHVGRHIMDKAICGLLKGRCRILATHQLHVLSRCDRIVVMDDGRIHAVGTFDELSRDNDLFKQLMSTASQDSKEDEEEATEVVEEEAEKQAQQEPTKPAAALMQQEEKATDSVGWTVWKAYIRASGSYFNALAILFLLAFANVVNVWTNLWLSYWTSNHYPSLSTGQYIGIYAGLGAGSALTMFIFSTYMSTAGTNASRQMLQLAMTRVLRAPMSFFDTTPLGRITNRFSKDIGVMDNELCDAMRMYAITITMIVSIMILIIVFYHYFAIALVPLFLLFLTASNYYRSSAREMKRHESILRSAVYARFSEAITGTASIRAYGVQNQFRSSLRDSVDTMNGAYFLTFSNQRWLSVRLDAVAVLLVFVTGVLVVTSRFDVSPSISGLVLSYILAIAQMLQFTVRQLAEVENNMNATERVHYYGTQLEEEAPAHIPSNPVPESWPPHGEITFDNVAMRYRPGLPLVLKNLSMNISGGERIGIVGRTGAGKSSIMSALFRLTELSSGRITIDGVDISTIGLHDLRSRLAIIPQDPTLFRGSIRSNLDPFNEHSDLELWDALRKAHLIDSDTKDSAVDASNPNGNANAQRLTLDTAVDEEGLTFSLGQRQLMALARALVRNARIIICDEATSSVDFATDQRIQETMAQGFEGKTLLCIAHRLKTIIHYDRICVMDQGSIAEIDTPLNLWEKEDGIFRAMCERSGISREDIVGQVEKE
The following text describes a protein:
Function:
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MVKNIKIFLSLFFVVVLGLLATTANSMVIGIDLGSQTFKVSLIKPGAFETVLNEQSGRKTISSVGWFKDERLFSSDSFSVWARNPKQNYNLIQAFLGIKYKEGLVEEISNGLPLGFKVKNDTVRNTVSIVYDDDTNYSAEELTGMLLRRVKDMASSYAGSSIKDCAITIPPYFTQQQRQALLDAAQLAGLNVLSLIHDVNAAALSFAMDRTFLEKNESVIFYDMGARHTSVSLVEFESHNEQIKGVKKNKTVSSASVKGIEWDEKLGGFDFDMVIVNHLKTLLKKQIPSANVDDIKITIKLLKEVGKMKENLSVNQQAQIFIGSLVDDHDFQATISKQQFEELSQSLIERSLLPLKKLILSTGIKLKDIEYFEVIGGGVRIPFIQQALKDYLKRDTLDKHLNGDEAMSNGAAFYAASLTHYFKVKEIKLKDILLNSVDVEINNNIINSGGAGETLLEETEDNEDNELNNSGNEQQQQQQPTINQGGLKDKKIQLFKVNSKLGIKKTVSFSSENGFSLFLNNPTINNPLATYTVSNVPTPGEKYNFTGKPKIHCSFRLTTSGIVVLEKAEAEITVSLIKPQPQQNKTSSSTSTTKKNTTTIETTDGGSEETTDETTTKQQQQQEKEEEEEVVVVEKVIEYIQKTIRVPLNFTIKYNGCVEPLSKELSQESNDRINKLDQVDRILRELRQERNNLESFIYETKDKLESNEEYLKCSTQQERDQLVEELDKTSAWLSDALDNDNTETEEYRKQLKDIKKKADKIVNRVSQYQLVPVALEELEDTVDKVKPMFEIASKDLNVTAEELKETTDKIQSVSDWVQEKKSEFKLADYSKDLQTSSFDIKFKLYDLERTIKEILKKKKKPVKPSSSKKDKSSKSSKGKSNSTDEKDQKQKEQKEQQQQQKEESQFQNDGAEEQQFEDDHKVHDEL
The following text describes a protein:
Function:
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSDEPVVKKTKVEDLPDTIVDSVYEKQLAEGRVRGVASIKPEYLVARASADARDAPPSVNDDLAEGGEKPEEKKKGGQNKNRSLKQRKDAIKMCSSALQFKEDGSPQECSYGDKCKFEHDLQKYLESKPKDIEGVCPVFDLTGQCPQGYKCRWLSSHRDSEGKLLVDEEKKKANADNKELNHVFKHLNPLQRKKYDLSKSDEAIKLIDAQIVRDEDDEQTKLEKKETIEIDTGRIRPSEKKKLDLKGKYIVSPLTTVGNLPYRRLMKDLGADVTYGEMALTLPLIQGHKAEWALTRCHSSEVTEGNHFGVQVTAPKHWQAIKAAQAVSELCTGISEINLNCGCPIDLVYRQGAGSALMDQQGKTARIVRGMSMVSGDVPITVKMRTGTGSTPTAKKLTARLLAEGQTAAFTLHGRSRAQRYTKLADWNYIREVADSVVNTRDDVREKSELDDHVISHPTWVVGNGDCYTWSDWHRAVDEAHVDSVMVARGALIKPWIFEEVESRQHIDKSATERLEYFQKFAQYGLEHWGSDQYGVNQTRRYLCEFMSFTHRYVPSGILEYLPAKMNDRPDLWKGRDEMETLLGSSDYRDWIKVTERFLGPVGDEFEFTPKHKSNAYPTESG
The following text describes a protein:
Function:
Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MLTTPEFQIVVLDTETSTHEYYIWTSQHFTNVTNSSYACPSTHPRQLFWPDLEAADGDSVPKALLPIANRPMIAYQLDWLEEANIRDIIIAAYPGARGKINGVVQSLLEGSTGTKVQIVEVPENSGSADALRTIKTKIKTDFIVISCDLITDIPVHYLINSFRLQNPTMTAFFYDAGNLEASTDRPAAKDDGLGEFIGIDDQSSRVLIMASKADLDDDLELRVSMIAKFPVVHLHSQLRDAHLYIFRKWVLDLVSKNKNLSSIKNDLVPLLLECQHRESVLKREGIDKLMAAGNSDLFARALMYSTSGHEPTPQNVTCNAVVYRDGFTARGNTVWSYSELNRHVVKHMTESRVQASAEVNAKAQVGHDSLVGEGTKIDERCSVKKSVIGNHCKIGKNVKITNSIIMDYVHIEDGVKIDESVVCNNAKVGAHALLKDCRVGAEQIVPSEIAPNLTIEFMLYDLAIGKGEVFAAGMNE
The following text describes a protein:
Function:
May be involved in 20S pre-rRNA processing.
Sequence:
MAAPMDIFRDSVKSVLDGWTVLQLAVQHGFGGVHSAAKAEWMVDAVSQWFQENADIDPCELEDFLAEVLNNEFDTVADDGSLAQVAQQICGSYRLCRQGRHQEVLSRIQQLPKAQLSGCVAATGPEEDDDDDDDGEEDEKEEEKDEDMEVTPSSSIENGPHQKTEAANTPNTSAQDMESQSQEDIDDGWTVVTKKKKR
The following text describes a protein:
Function:
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
Subcellular Localization:
Cytoplasm.
Sequence:
MNITPIHDNVLVSLVESNKEEVSKKGIITSLASNDKSDANANKGIVIALGAGPAYGKTEKPKYAFGVGDIIYFKEYSGISFENEGNKYKIIGFEDVLAFEKPESGKQRKR
The following text describes a protein:
Function:
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
Subcellular Localization:
Cytoplasm.
Domain:
The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
Sequence:
MALRLPALLDANAPWGPPSTVPEDLKFDDVPYAPFSKGDKLGKVADWAAETKDGKDQKRTQFGKNFRDPYHAYGASSASFFTNEDAEELSSFSVVDNAKNANKPRGTATVLKTRGGAPRGGSFAGRGGSQRGGRFQNQPGRGPVGGQRGPNPRFGKSKFGWRDFDKPQRIRNASVDITDDWTEIQEITYSEMQKLSYDVAQGVEIDTYGDLFPYDRKFDRTNNITKLAHLGRTVFNTTTSEDPIMQELAKDPANRIFITDTILSQIMCTTKSVAPWDIVITKKGEQLFFDKREGGPLDFITVDENAADPPADSTDKDNINSSANLGFEATLINQNFASNAITEDPKSKVSYKANPFSNNDSNVLCHAYKYKKFNLSDDPEGAPLNLILRTEVDALGPDGTTLNLRVLNEYGSSEWKNKFNTGRGAIIAAELKHNLNKISRWTVQSILGDVDQMKIGFASRVSPKDNTQHNIIGVVSREPKQFAEQINVNLNNGWGIFKSVVNIATAKDDGKYVLVKDPNNPAVKIYKPAAGF
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MEKKRKKEKDGATTSRPPRIPDSAAYKALEDLVSPHIDSFDYFVQRGLVEAVKGIAPVEIEQDGFHSGDFGFSLDVVLALTLDKPVVQPPVKDLKEKAMEHRLLPKECRQGFLSYTGALNIQLILDYGSMTRYHQLSLGKLPIMLKSSLCHLRGLSPQKLISLKEEGTEMGGYFIVKGIERIIRKLIVPKRNHIIAIRRNAFQNRGAGFSDIGLMMRCVRPDQTGSTIKLYYLHHGTARLGFVIRRQEFVIPVGIILKAFMDTSDREIFEQLSGIHVQGQEQSKGAVGSQLISQRARIIIEETQRQPCLTRLDCLRYIGETFRTPLEALSSMSNAEVGEDVLRRFVFVHLDNFRDKFNLLIHMLHKLFAVVDGSASIDSSDTLQHQELLLPGHLMNIYLKDRLEDWLYRCKRLLQREMQLKEEFDLSDHAKVLKIVEKNNAVDIGKRIEYLLSTGNIQSQSHMDLQQANGFSVVAEKLNFFRFISHFRSVHRGAFFARQRTTSVRKLLPESWGFLCPVHTPDGEPCGLLTHLSSLCKISTDLDQNNHPKDPKVPIDLEIGYVPCTYAGAYPGLFLYTTPSRFLRPVKQLDTGAIELISAFEQAYMEIACPDGGNCGRTPSAPPATHIELHPTAMLSVVASSTPWSDHNQSPRNMYQCQMGKQTLGFASQALKFRTDHKMYNLQNPQSPVARNVNYKKYNMDEFPLGTNAVVAVLAYTGFDMEDAMIMNKSSMERGLAHGQIYKTEHVDLSLLQKKSDGIVNLFSRPTGKRNIHNFLDVDGLPHIGQTMHNGDPYCSVLNTMTGDAKLHKLKAAENVVIDSVIAIGHGRDPLQKIAVKFRHDRNPVIGDKFSSRHGQKGILSQLWPDIDMPFSAVTGMRPDIIINPHAFPSRMTIGMLMESMAAKAGVLRGEYVDSTPFRSSSAALDAKDGKTGSGYKGKDKHYPAISEFGEQLAQHGFNYHGTEVMYSGLLGTELTCEIFIGVVYYQRLRHMVSDKFQVRSLGAINPVTRQPVGGRKLGGGIRFGEMERDSLLAHGAAYLLHDRLHTSSDYHVGDVCTTCGSLLSTLMVPSKQPAVGARNKPKKATCKVCQSNAGVVKVAMPFVFRYLAAELAAMNVKLTLKVASA
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.
Subcellular Localization:
Cytoplasm.
Sequence:
MRIPTTIHSNDTSTLSTTLTNLNLQHLSSKITLSQYTPSTTSIEKNPLRGALSEVLTLLPPSILSALNLTPHRLAAAFPDAYSIYPPLLLLPHNAFSSPLWRALLTAHPASAASLQPLWRHVAQKMGVSHIAINSPIPLQNGENTMRSPVNITPIYGSFGPSPSPRTLSHPSPADFDKALWASACQNGITQSWAPMYTMFSRGNIREKTRILSFPSQDAGSVVDMYAGIGYFTLPYRRRGFSPIICFEVNPWSVEGLRRGCVANNYSYKIFTRMDMHEWDEEDFTSNGETVKDVYIFHLSNTHARPLLAPHISSLPPVRHVNLGLLPSSRDSWRDAVGLVRREGGWVHAHENVGVGEVESRRGEVEKVFQRWVDEMDEVVESEVDGVVSGRKAEVRHVERVKMYAPGVVHCVFDVWVEGRGE
The following text describes a protein:
Function:
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MDDTVLEPTLQNVLDQTSLKWIFCGGKGGVGKTTTSCSLATLLAAVRERVLIISTDPAHNLSDAFRQKFTKSPTLVEGFKNLYAMEVDPTVEVDDLQIEGLGGGMFSDLANSIPGIDEAMSFAEMLKLVQNMDYSCIVFDTAPTGHTLRLLQFPSTIEKGLGKMASFKSKFGGIINQATRMFGAGEEFGADQMMEKLDTMKALIENVNAQFKNPVDGVSSVSSLEYCCPKKQRTQTGREPDESEYEAFLSPQALTTFVCVCIPPFLELTTFVCVCIPEFLSLYETERLVQELAKFEMDTRNIVINQVLFQEEVRGSKLLQARLRMQQKYLDQFYDLYEDFHISKLPLLPEEVRGVPALKAFSQNLVKPYSPAEESSPEDTTTRSVDGSVDLKAEVQRLERRVEELEAELAVLRKGKSKVMDVD
The following text describes a protein:
Function:
Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQVASATPAATVRKAAAGDELSEFFALTPDLLEVANASGNASLQLQDLWWELGLELPDGAAPGHPPGGGGAESTDTEARVRILISAVYWVVCALGLAGNLLVLYLMKSKQGWRKSSINLFVTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVARYHSVASALKSHRTRGRGRGDCCGQSLRESCCFSAKVLCGLIWASAALASLPNAIFSTTIRVLGEELCLMHFPDKLLGWDRQFWLGLYHLQKVLLGFLLPLSIISLCYLLLVRFISDRRVVGTTDAVGAAAAPGGGLSTASARRRSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFQCQVYAFPVSVCLAHSNSCLNPILYCLVRREFRKALKNLLWRIASPSLTNMRPFTATTKPEPEDHGLQALAPLNAAAEPDLIYYPPGVVVYSGGRYDLLPSSSAY
The following text describes a protein:
Function:
Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasmic vesicle. Membrane; Peripheral membrane protein.
Domain:
The N-terminal C2 domain associates with lipid membranes upon calcium binding.
Sequence:
MFQVVVTRLSSRALPALAAVLLLRRDEEGGNKPRWDRRTKSWRKEVHPYYNLSVTVLRAKNIHGADLLSKADCYVQLRLPTASPMASRTAVVYNSSDPEWNETFNYRVHGAVKNILELTLYDRDVVLDDKLSSVVFDIGHVKPGQSTKRNFKLGPKESLEVEFSLEKSKDPPTQIITNGVLVAHPCLCVHGNIHKGGSLSAPIGNQQLNLSMPGSYEKQISTPFSALSTQEQGVPFVFHADKGISPQLNVHLLKTVRLGENDLAPELEKQTFLVGESSVPVSSLPEGKEQGINLQLSKDQNLEMNVKTEEDNRVLDIRLGFELSLGEREFLEKRKKVAARCLKEVLKLDNTPGANEVPVIAVLGSGGGTRAMTSFYGSLLGLQKLKLLDSVTYISGVSGSTWCMSTLYEDPDWSQKSLQEPISRAKTSVTASKSGAFSAERLKHCTQELIAMEKDGHMVNFTDLWGLVIEYFLHQKENPAKLSDQQACVSQSQNPYPIYAGVNVRVDINGGDFAEWCEFTPHEVGFRKYGAFVRTEDFASEFFMGHLIHRRQEPKICYLQGIWGSAFAANLDEIWSRAAGTGIRWFNSLTDAIRVIDDCRKLHLRDSSRLKTRLVMPGGFVSSMFQEIFKSRFTAGEWYNFTRGLYLYKDYLGVREFLAWKGTHLDAFPNQLTPMEENLYLVDGGFSINSPFPLVLQPERDVDVIFSFNYSWDAPFEVLHLSSTYCRERGIPFPEITLTKEDEKQPKECYVFMDHNNPRTPIVLHFPMVNNTFQNFIEPGVERKTEEEKLNGEVDLNRKESPYRTKNFTYEPQHFDRLVAVNQYNVLNSSEQISGALKAAVARRKNKLAKLPPKRHV
The following text describes a protein:
Function:
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses.
Sequence:
MNSTLNRRLAQTSTGVALLPCPRLHRLQTVSHSPIQAAAPCPARAAEQLPSLTSSRAVAAAAGRQAEAASATNDRKRTRLAADKSPELIDPQLLAPIPMPTEYQQTLWASFTIAGVGLHSGEYAVVRVRPAFAGEGRYFVRVPEGTNAARGEESLVRMLEAGAGKQPEEEEAMDDTATREYKRELIAAYQEYVDAQEDDGFNGTFADYMNGKSYVALLQRLREEGPPRFSFSEAEAPQPRGEDEPYVEAALANITEPNPFTTALAKGDVEVLGVEALLSALEACGVDNARIEIEGGAEVPVIDGSAGGWASQIQTSGLTHALPRDDLPVPGGEFPAPADGEEAAAGDAEARKQRVCKMVLRPQEVVSVQRGASFVTLYPEDTFRLTVGLDRHLEAPVIGKQWFSWCMFEDLHYMHSLADARSWVSSPQQAMAMRDAGWLLGGTEGAMLIGNGDSWYDHTIVRHPRDEPARHQMQDLIGDLSLLARHGHSGLPLGHVVAYDADHELFAAFVERLQELTTEEDWVPIQDIAGPSVATDYEELLGSLLEGDEGEDDEGEGGEGAQLADQGAEEDEDEVYDEYEEDEGEGEEYDEYEEEGEEAPGPEAGRARR
The following text describes a protein:
Function:
Participates in a novel circadian output pathway that conveys temporal and food status information to feeding-relevant metabolisms and activities. Involved in male courtship behavior. In the brain-associated fat body, transcription is enhanced by the dsx and fru male-specific isoforms and repressed by the dsx female-specific isoform.
Subcellular Localization:
Secreted.
Sequence:
MFAIAFAVVLCLLVSVDAKFPEDPKPCKYGDGECIMKLCNTLFSENSAEGDPGLNLMQLDPLKVDRMVISQGESSSPVGITLTFTDNLLYGIKDQRIVKVKGFGRDLTAKHEVKIVTKTFSLVGPYNIQGKVLILPISGTGQSNMTMVNVRAIVSFSGKPLVKNGETYLDVTDLKITMKPESSHYHFSNLFNGDKALGDNMNVFLNENSEAIYKETAKAIDRSFGKLYLGVVKGVFSKLPYAKFFADES
The following text describes a protein:
Function:
Steroid phosphatase which catalyzes the conversion of inactive phosphorylated ecdysteroids into their active forms. Shows high activity towards ecdysone 22-phosphate (E22P). Has lower activity towards other ecdysteriod phosphates including 20-hydroxyecdysone 22-phosphate (20E22P) and 2-deoxyecdysone 22-phosphate (2dE22P). Also has protein tyrosine phosphatase activity.
Subcellular Localization:
Cytoplasm, cytosol. Note=In 72 hr non-diapause eggs, detected mainly in the cystol surrounding the nucleus of yolk cells.
Sequence:
MANLPPRKVTSASKSKQDVSPLQILLQMGFRRQRALKALAATGNRSVQLASDWLLTHVSDSNIDADDPREYIFYASPTGPLLSQLLEFWDKSKSTCGWNGAHNFLPHITLVSFFKAPDDTSLNLAKAVRQVVENVGDPPKCTLKLEPYVSHNFMGLFISEEHAEYLKKIAVQYVKQVSSVSSINLEAHVKSLHITLAYHFEESSYEDLKTLVEEMQPVEHSSWELRLYSRDPRFANHQVYKVTQGYSPQASDELELVLGDYIYIEEKEFDISPDGWVHGTSWLTGLNGYLPAVYTRRTAETDAWTLLKAVSLGNNCSDCKSESGSNTDSEMAGTYPHEDAADLAYKKSEETYQEWDKYWSEVMNSRSDSILTITQGLPMNWELSKAAEEMKNNITNGTSKSRRWVFALRHGERVDLTYGPWVPHCFENDTYVRKDLNLPLKLAHRAGGKGGYVKDTPLTRLGWFQAQLVGEGMRMAGVSIKHVYASPALRCVETAQGFLDGLRADPSVKIKVEPGLFEFKNWHMPKGIDFMTPIELCKAGLNVDMTYKPYVEMDASAETMDEFFKRGEVAMQAAVNDTEKDGGNVIFIGHAITLDQMVGALHRLRDDMEDVQPYEIGRNLLKVPYCALGAMRGKPWDVVSPPCPPSINSSSGRFDWRILIK
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MEGSSELYSISSSSSKSMGETVNISNSISRGFSGSSIISSNSNSNSSRNRSKEMESLSLEISKYPRDLLQTFLSSNSGERKSGNRSADDDDDDDDDGLNLGLGLSLGGKFGVDKSKNLGGLIRSSSIAGTMPFFREGGEDDSGAAVTMAAMALPPSLGNNNNNSNNHLVRTASLPVETAEEWRKRKEMQTLRRMEAKRRRSEKQRVLKESGIGVGGGGGEEKGVEGLKLRARLEREQQCLGLTSKLIGSSSIGTLFKPPPSGNHNHLEVKGRRTTFGSLQGFLIAQDQAQTQTQPNQGSSQGSGESQGSDASELESKTHQGSSSCDTRSSPGTHSQQERTGSQESEFHRASRAEQTENKKKETISATATASASSGNAIEDMPCVFTIGDGPNGRKVEGILYKYGKGEEVRIMCVCHGTFFSPSDFVKHAGGTDVDHPLRHIVVTPSSTSPIL
The following text describes a protein:
Function:
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHGHRTLTPARCRLPLPRLKKDRTDHAVSTPCPTTSGPVQTTHAPVDGLSHRFPSIRPGSSSPIPLLPRSSPASTPRQRERARRETTRSRAEMSSDSSSWARALVQISPYTFSAIGIAVSIGVSVLGAAWGIFITGSSLIGAAIKAPRITSKNLISVIFCEAVAIYGVIVAIILQTKLESVPSAQMYAPESLRAGYAIFASGLIVGFANLVCGVCVGIIGSSCALSDAQNSSLFVKILVIEIFGSALGLFGVIVGIIMSAQATWPAKA
The following text describes a protein:
Function:
Functions as a flavanone 2-hydroxylase that catalyzes the direct conversion of flavanones to 2-hydroxyflavanones. In vitro, can convert naringenin and eriodictyol to the corresponding 2-hydroxyflavanones. Generates 2-hydroxyflavanone substrates for C-glycosylflavone biosynthesis by the glycosyltransferase CGT.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MEEGVVGGGGAAVLVALLVTVVLAVMRSAGSRSSKRGRLPPSPMALPIIGHLHLIRPPPHRAFDRILARHGPLVYLRLGPSTHCVVIGSADVARDFLKFEASIPERPPTAVTRQLAYGKAGFAFAPYGAYWRFVKRLCMSELLGPRTVELLRPVRAAELADVLRAAQSAAERGEGVDMSHELVRMANNSIMRMVASALPGEMAEAARDCAKQVAELVGAFNAEDFVAVCRGWDLQGIGRRTNEVHARFDALLETIIEAKEEARRRSLRLGRRESSSKDLLDMLMDAAEDDTAEVKLTRDNIKAFVLDIFTAGSDTTATTVEWMLAELVNHPECMAKLRGELDAVVGRSRLVGEQDVARLPYLQAVLKETLRLRPPAVFAQRVTVEPVQVRGYTIPTDTQVFFNIFSIGRDATYWDQPLHFRPDRFLPDGAGATVDPKGQHPQLMPFGSGRRACPGMGLAMQAVPAFLAALVQCFDWAPPPSQPLPLDMEEAAGLVSARKHPLLLLPTPRIQPLPSFYS
The following text describes a protein:
Function:
Required to maintain the full capacity of the mycobacterium to respond to oxidative stress via the degradation of oxidation-induced damaged nucleotides. Hydrolyzes all canonical (d)NTPs, as well as mutagenic dUTP and 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-oxo-dGTP). Also involved in the transcriptional activation of RelA in response to oxidative stress.
Sequence:
MIVVLVDPRRPTLVPVEAIEFLRGEVQYTEEMPVAVPWSLPAARSAHAGNDAPVLLSSDPNHPAVITRLAAGARLISAPDSQRGERLVDAVAMMDKLRTAGPWESEQTHDSLRRYLLEETYELLDAVRSGSVDQLREELGDLLLQVLFHARIAEDASQSPFTIDDVADTLMRKLGNRAPGVLAGESISLEDQLAQWEAAKASEKARKSVADDVHTGQPALALAQKVIQRAQKAGLPAHLIPDEITSVSVSADVDAENTLRTAVLDFIDRLRCAERAIAVARRGSNVAEQLDVTPLGVITEQEWLAHWPTAVNDSRGGSKKRKGMR
The following text describes a protein:
Function:
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNAKRPVNLDLTKFHFPPMAILSIGHRISGFVLFLCMPLMFYLLHRATASAESFYHLHQLLLHNGWIKLAVWIMLSATLFHLFAGIRHLAMDLGFWESVPEGRISAYTVFVVSFIAIVLAGVWIW
The following text describes a protein:
Function:
Transcriptional repressor.
Subcellular Localization:
Nucleus.
Sequence:
MAEASSLGRQSPRVVSCLEHSLCPGEPGLQTTAVVSMGSGDHQFNLAEILSQNYSVRGECEEASRCPDKPKEELEKDFISQSNDMPFDELLALYGYEASDPISDRESEGGDVAPNLPDMTLDKEQIAKDLLSGEEEEETQSSADDLTPSVTSHEASDLFPNRSGSRFLADEDREPGSSASSDTEEDSLPANKCKKEIMVGPQFQADLSNLHLNRHCEKIYENEDQLLWDPSVLPEREVEEFLYRAVKRRWHEMAGPQLPEGEAVKDSEQALYELVKCNFNVEEALRRLRFNVKVIRDGLCAWSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQTRLGRRKYVPSGTTDADQDLDGSDPDGPGRPRPEQDTLTGMRTDPLSVDGTAGGLDEPGVASDGLPSSEPGPCSFQQLDESPAVPLSHRPPALADPASYQPAVTAPEPDASPRLAVDFALPKELPLISSHVDLSGDPEETVAPAQVALSVTEFGLIGIGDVNPFLAAHPTCPAPGLHSEPLSHCNVMTC
The following text describes a protein:
Function:
Transcription factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Also plays a role in DNA break repair, participating in the DNA damage checkpoint response. Promotes transcription of PHB2.
Subcellular Localization:
Nucleus.
Sequence:
MRESPRRPIILKRRKLPFLKSESDLGCDEADGTRCKTTSTQSTARSFPDGIRVMDHPTMPDTQVVVIPKSADLQSVISVLTAKGKECGPQGRNKFILLSGDTSLEESKTLGCFSTELGSELGKVKKESECFPLDDSLTNIQWLGKMSSDGLGSEKCPNKDNPNDSQQQSKGPEKENDPHSERPPYSYMAMIQFAINSKNNRHMTLKEIYNWIEDHFPYFRDIAKPGWKNSIRHNLSLHDMFIRETSPDGKISYWTIRPEANRCLTLDQVYKPLGDPLTPTCPQIPQVAIHQQQKRGAPELKKAIPALGGTERKMKPLLPRTDSYLVPIQLPLGQSLFLPTSSPVSLSTPPQTQNSSTPSSSKRVRIAPKVSQSDLSSVLLCKPASQEIKEEPVFQPVTSSEAPPPKSRRTDNSSSRRKQRLVLPATEEPVLLYPDSTLFDSGVISDISTFQDTREADPKPELDSPNREYSFKTPIKSSHPSSSTPSKLPTVTLEPWRITPVGKGGVLDFSPIRTPTGPHVTPQRNQHTSLSFTSTPFKELPLFNSPRELLTCSRSSPKRSAPACSRELLQVGAANRSLTEGFVLDTMNDSLSKILVDISFSGLEDEDLGMGNISWSQFIPELK