lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
Sequence:
MASSAETTETSKPSSETTAETTTKSTKIITLKISDEAIFEVEDSVAMEILVIVKSFLKDQSPSTKIVPLPNILAKPFSQFIEFCKEHVMFKENPDKEKQKKISEFFLKEKSNEELLDMITVAKYLEAEDLLDLLSQAAADRIQNKSVEYMRKFFGIENDFTPEEEAKLCEERSWAFEDVDEGY
The following text describes a protein:
Function:
Removes the formyl group from the N-terminal Met of newly synthesized proteins.
Sequence:
MGLLLGSLQARARRCTGPALLWREGVAGGSARACSSTPAWDGLEGPARRRSYWRYLRRLVQGAPEPPYSRVCQVGDPALRAVAAPVEPAQLAGPELQRLVQRLVQVMRRQRCVGLSAPQLGVPLQVLALEFPEALCRACAPRLREARQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLAYVPRFQAVQISGAGRRGPWGGWGWILEESRWCGRRVGGQPASSSMKWTTCRAACSLTKWTAGHLQTSTGWK
The following text describes a protein:
Function:
Component of the eIF2 complex that functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex (43S PIC). Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF2B.
Sequence:
MADDEVKDEVPEITSFDPTKKKKKKKVVIQDPADESVDKLAEKTEALSVSEGLDFSNLKKKKKKPVEGNTFTDESGDAGDDFDGHIDGDEEGEGIVLQQRYPWDGTDRDYIYDELLGRVFNILRENNPELAGDRRRTVMRPPQVLREGTKKTVFVNFMDLCKTYVTVLFPLLCSLIHLYARVRAHTHIMHRQPDHVMAFLLAELGTSGSLDGQQRLVVKGRFAPKNFEGILRRYINEYVICLGCKSPDTILSKENRLFFLRCEKCGSGRSVAPIKAGFVARVGRRNAGT
The following text describes a protein:
Function:
Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.
Subcellular Localization:
Membrane.
Sequence:
MLTSHFPLSFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHALRRWASGVPGIGDKRQPLWPDDLFGSISHCASTALAVISRQRVGVDIEKIMSQHTATELAVIIDSDEPQILQASSLPFPLALTLAFSAKESVYKAFSDRVSLPGFDSAKVTSLTATHISLHLLPAFAATMAERTVRTEWFQRGNSVITLVSALTRWPHDRSAPASILSAIPR
The following text describes a protein:
Function:
Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MGQCSSATKMRRKRKREEECCRESMERRNKGCLAMVKERRSRFYIARRCILMLLCWHKYANS
The following text describes a protein:
Function:
Involved in the regulation of homocysteine metabolism.
Sequence:
MAEAVKILSGGLSTELENSGFLLQGDPLWSARLLQTNPQAIKNVHTSFLKSGAEVLSTATYQASVKGFQEHLGLSIDEVAELFHVGVRLAKEAAAEIKDNRNILIAGSIGPYGAFLSDGSEYTGNYLRNMSVEELKDWHRLQMQCLASAGIELFALETIPGQKEAEALLELLREFPNTNAWLSYSCRDMSSTSYGDAFEKAVGIAHKSKQLVAVGMNCCPPTFVSSLLTSANKNRGLDIGWIVYPNSGKIWDHNLGWQGGGTEKTLSEYALEWVNLGAKWIGGCCTTTPSAIATLLHTLRPHAADLH
The following text describes a protein:
Function:
Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
PFDKPRNISLSLIQVEIQMEKFEGYSEKLKFPRQYFVYPLLFQEYIYVFAHDYGLNGSELVEIFGSNNKKFSSLLVKRLMIRMYQQNFWINLVNRPNQDRLLDYNNYFYSEFYSQILSEGFAIVVEIPFSLREQSCPEEKEIPKFQNLRSIHSIFPFLEDKFLHLHYLAHIEIPYPIHLDILLQLLQYRIQDVPSLHLLRFFLNYYSNWNSFITSMKSIFILKKENKRLFRFLYNSYVSEYEFFLLFLRKQSSCLRLTSSGTFLERIHFSRKMEHFGVMYPAFFRKTIWFVMDPLMHYVRYQGKAILASKGTLLLKKKWKCYLVRLWQYSFSFWTQPQRIHLNQLANSCFDFLGYFSSVPINSLLVRNQMLENSFLIDTQMKKFDTKVPVTPLIGSLAKAQFCTGSGHPISKPIWTDLSDWDILDRFGRICRNLFHYHSGSSKKKTLYRLKYILRLSCARTLARKHKSTVRAFMQWLGSVFLEEFFTEEEQVFSLMFAKTTYFSFRGSHSERIWYS
The following text describes a protein:
Function:
Transcription activator that acts as a flowering master switch in both long and short days, independently of the circadian clock. Promotes flowering upstream of HD1 by up-regulating FTL1, FTL4, FTL5, FTL6, EHD1, HD3A and RFT1. Seems to repress FTL11 expression. May recognize the consensus motif 5'-TTTGTCGTAAT-3' in target gene promoters.
Sequence:
MPPPHPTDAEAGPEQVAPTEAVPLAAAAPAPVKKKRNLPGTPDPDAEVIALSPGTLLATNRFVCEVCGKGFQRDQNLQLHRRGHNLPWRLRQRGPGAAPPRRRVYVCPEPGCVHHSPTRALGDLTGIKKHFCRKHGEKRWACPRCGKRYAVQADLKAHAKTCGTREYRCDCGTLFTRRDSFVTHRAFCGALGEETGRALAPPAPPSPRPPDLEAEENVDNDKEEEENEDSALAEVEVPQRVEVAVPEEPEPEPQRIPSPPPLPQEPPCRPSPPPLPQEQPRRVSPPPLPKEPPCHHPTPPPLPKEPQRLPFPPEQQAVVALVPNVDEPEVAAVGTVAAKLEDETDQDETTCFQEADQYKDAELEVSNLLDKDTPMLPCFLPSPSEAIGTDGSSTTCGAGGSVSNSIVPSTTTNTFAGLFASATTSTTSQSRSLRDLIGVDPTFLCLAIGAPSLFPQTSASNSGTFAPPPAPHMSATALLQKATEAGATQSSSSFLKEFGLASSSSSPRPKQQQPHGRVAETSTDPWQYRNSNQQMEMERHQSHQRREMESSSQPWQHPRITQQMEMERHHQRSHQQREMESSSQPWQHPRSTQQMEMERHHQRSHQQREMESSSQPWQHPRSTQQMEMERHHQRNHRQRETESSSQQWHHHHHHPNDQMMGLESYRSNQQMEMDPSSQQRWAQHQRSNQQQQMEMMERHHLSNQQIRSTQQMERRAMVSGGGLGLGLAYESGNPGLPLPDLMTGPSPLLGPKPATLDFLGLGIGGTMGGSTASRGLPALMVGRELDMGPSAQVPPAAAAAPWEDAKRKTNGRTIL
The following text describes a protein:
Function:
Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. May play an essential role in the transition from the vegetative to the reproductive phase of development. May be a positive regulator of ABA signaling.
Subcellular Localization:
Nucleus.
Sequence:
MAMKAPDPGGSGEILPSTPSLSETTSGGAAAASKSAQLPSSSSDIDNIHVPSYSSWFSWTDINDCEVRSLPEFFDSRSSSKNPKFYLYLRNSIIKQYRDDHPRKISFTDVRRTLVSDVVSIRRVFDFLDSWGLINYNSSASAKPLKWEEKEAGKSAGDAASEPATTVKETAKRNCNGCKAICSIACFACDKYDLTLCARCYVRSNYRVGINSSEFKRVEISEESKPEWSDKEILLLLEAVMHYGDDWKKVASHVIGRTEKDCVSQFVKLPFGEQFVKESDSEDGLEMFDQIKDSDIPESEGIDKDGSSPNKRIKLTPLADASNPIMAQAAFLSALAGTNVAEAAARAAVRALSDVDYEADKNASRDPNRQDANAASSGETTRNESERAWADAKSLIEKEEHEVEGAIKETVEVEMKKIRDRIVHFEKLDLEMERSRKQLEEVRNLLFVDQLNIFFHTRKARKTEDRIEC
The following text describes a protein:
Function:
Required for early specification of the kidney glomus, lying upstream of wt1 in the pathway controlling glomus differentiation. The balance in levels and expression patterns of binding partners such as lhx1/lim-1 influences differentiation into glomus or tubule derivatives. Involved in specification of serotonergic neurons.
Subcellular Localization:
Nucleus.
Sequence:
MDIATGPESLDRCFTRGPSDCAKMLDTIKMEDHPLRTGTATLGVLLGSECQHQAVCEGCQRPISDRFLMRVNEASWHEECLQCTVCQQPLTTSCYFRDRKLFCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLSCFCCCVCERQLRKGDEFVLKEGQLLCKSDYEKEKDLLSSGSPDDSDSVKSDDEEGDVKPGKGRVNQGKGSDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKIKKLARRHQQQQEQQNSQRLGQEVMSSRMEGMMTSYAPLAPSQQQIVTMDQNSYSTDPFQQGLTPPQMPGDHMNPYGNDTIFHDIDSDTSLTSLSDCFLASSEVTSMQARVGNPIDRLYSMQSSYFAS
The following text describes a protein:
Function:
Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.
Sequence:
MAPPIVLNVAEKPSVARALAQVFASTPGSRPRPDQRTAAQIFECDNVQFPCLYQQGNGTPANGRNEPHTMITTSVRGHLASQNFGPSFGWTRCAPVALFDAPIDTSYSEDMEPLERMLRQLSQRASALILWLDCDREGEAISDEVRAVCLKGNPRLGTMNRIYRAKFSTVLPGEIERALRTLGRVNENFVAAVQARSEHDLRVGAAFTRFQTLRLQKKFDGFGERGVISYGPCQFPTLGFVVERWARIETFVPEDFWFIEMTIRLNEDGSVSRSIRLNWKRVRLYDRVMTIALYDACLEAGAAVIVSLTGRPKNKWRPIPLATVELQKRASKYLRIGSEELMQKAEELYQQGFISYPRTETEKFRPEFDHHALIQSFQAVQGEFGNYATSLLSNSNFQNPRAGQNDDNAHPPITPAKAVDPQTIADPIQRKVYTLVVKHYLACCSRDAVGRETELTLKIASEEFVAKGLMILERNWLEIYQPFERWSTGQGELPKVRVGSRIVPTTLVMNEGQTSAPTPISEVELISLMDRNGIGTDATIAQHITTICEREYAKKDQNQRFHPTKLGIALVEGYNSMGYQLNKPDLRREMEAECSAVAAGRKTKDQILGPVIAKMLHCFRTANAEVEKLDTAVARHFDKLGSNRNNEYSVLQADFSVCGTCNRMMTLKEQRN
The following text describes a protein:
Function:
Probable inactive serine protease which plays an essential role in the innate immune response against bacteria and protozoa infection by activating the melanization cascade. Binds to the surface of parasite P.berghei ookinetes and bacterium E.coli where it promotes the accumulation of mature TEP1 which leads to the melanization of the microbe.
Subcellular Localization:
Secreted. Note=Secreted into the hemolymph.
Domain:
The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure.
Sequence:
MAFSLRIGIRTTDSKRCLVLLVLVVLLTVLACLPPSVEGNFPVGKFRRCNNNKGICVSREQCLNGQINTVGHTQIEPRLLNDDDIDECDVYGMQCCNLPSTNVPADSDEEEQEEEEKEKKGGTVTTTTTEEPDDPDWSRQCGQRTDVTERADQDGETNRFEFPWSVALFSKAQFFGKVRKEFLCGGTLIDDYLVLTAARCVNQKDRNTLVVQLGRWNLDAGKESRMQEIAVEELIIHRGYVLSSHLHNVALLVLANGAQLGRAANRVCLPDHSVQFGPDTLCYVVGWSNSPSPNTSNRQLKLRSMVAPVQECTATIRRSTGAWDFRLLSENICTTYLDDTVPCERAPGSGFVCESPTLPGQYFLVGIASYAVRQCHKYRAHDVFVHVPDYIEWVDGHVVNQSRQTSFYRPDPISFD
The following text describes a protein:
Function:
May be involved in growth and differentiation of hematopoietic cells.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSRHTDLVRSFLEQLEARDYREGAILAREFSDIKARSVAWKSEGVCSTKAGSRLGNTNKNRYKDVVAYDETRVILSLLQEEGHGDYINANFIRGIDGSQAYIATQGPLPHTLLDFWRLVWEFGVKVILMACQETENGRRKCERYWAREQEPLKAGPFCITLTKETTLNADITLRTLQVTFQKEFRSVHQLQYMSWPDHGVPSSSDHILTMVEEARCLQGLGPGPLCVHCSAGCGRTGVLCAVDYVRQLLLTQTIPPNFSLFQVVLEMRKQRPAAVQTEEQYRFLYHTVAQLFSRTLQDTSPHYQNLKENCAPICKEAFSLRTSSALPATSRPPGGVLRSISVPAPPTLPMADTYAVVQKRGASAGTGPGPRAPTSTDTPIYSQVAPRAQRPVAHTEDAQGTTALRRVPADQNSSGPDAYEEVTDGAQTGGLGFNLRIGRPKGPRDPPAEWTRV
The following text describes a protein:
Function:
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
Subcellular Localization:
Nucleus.
Sequence:
MKTLALSFTAQEQGGDPSRDWLTKSQLLLMAQPLCDASFTVPPADSHYTAWSSMATLLRKGLVSKQGCPAKYSLTDEGQRLASLLLEPGKNGSQNTLASPAEQPTQDPCSGGTSLGSLMEMPQSLEVLMLVDCGEACAGSQERLIRELRSLGVAHEIRRLSVGDFAWLGRSRSGLSCREWLLGPLVERKRTDDLAKSIQDGRFHEQKVRLVASGLSPLVYLVEDAGGNGGGPLPEAALRQAVLNTQVSDGFLIKATRDQADTARFLGLVSRHLEQQVASRPPSELLAGKPTWEEFSASSIKNKGLQVREMLAKHLLQIKGFSLDKVSRLVQEHPSPASLLAACERLDPSLKSKATTSKGSG
The following text describes a protein:
Function:
May function as sodium-coupled metabolite transporter across the chloroplast envelope.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Plastid, chloroplast envelope.
Sequence:
MDLVANVTDDIRVWGTGCTTKGANITVTYSVFFLNLLCIHLATKFLHEFLRRYGQPRIVSEFIIALMVGNVRWIGSTLENHVGRVLNVVGQFSMICYLFVLGLEMKPRTIFRRPSWDAAIAYSGVITTFGVCFSFYRLLLDLEYGFSNHLDYHFLIALALILSNTASPILTRLTTDLKIGKSHIGRIVVNAAILNDMVNTLITSVGIAIMKSPHVKLDRDLSDGYTQELLGLSWVFFVIFAQTMFVIIIVPHFAEWINERNPEGKPMKGFDLALSLAVVMALTQFATVVKFDLAFNAFLIGLAFPKEGRLTTMLISKINFMITTFGLPYFLCAIGMQAHLGAWDSGTDMYGTKWTFLRSLLKLLILVTIGTVGKVLGSFIVAMIYGFKFTEAIAIGLLLNVKGYFHILVVYLAFKSGFINANTFIIFLFVIISTVIYIPLVVRLVLKRARRSLQRPLMTLQGLDPSAEVQIVMGIIGPQHVSSTLSIVEATRGQSTTPLTVYAMDLVEKADSSVISSQDVYVEGNTVEEGISRMREETGLAFENYVQDGGEGLTVVRLQAIANIGNMHEDLCRAAQETASVLIVMPFHRTQQIMEGGNRRDMNHPGLRHINRKVLYHAPCSVGILVDRGLSEVEAPSKVAIIFIGGSDDREALVLAGRMASYPAFQLTVVRFLQESGAETKLARTRGLVIEKTVQEKEMHLDDECFAKFFETHIAGGRVGYLEKYIGSGSEAVVVLKALDGQYRLFIVGRDGCRNPVLTAGMGDWAECPELGPVGDVLSSSDFSDKASVLIIQQHDMERDQDFGDDDLK
The following text describes a protein:
Function:
Required for junctional attachments between hypodermis and muscle, and between the apical epithelial surface and the cuticular matrix. Essential for enclosure of the embryo by the hypodermis, hypodermal integrity, embryo elongation, and maintenance of hypodermal morphology in fully elongated embryos.
Subcellular Localization:
Cell junction, hemidesmosome. Cytoplasm, cytoskeleton. Cell membrane; Single-pass membrane protein. Note=Detected in intermediate filaments and hemidesmosomes.
Sequence:
MRWVPLVLLPLIASAATTYQHRQTYSSLQCRVNDPLSCNQAKSEVCVFVNGQYRCECPVGVSRLADGRCLVVNECARPSLNACHKDAQCVDLAEGYTCRCNSGFADTSPDKVNKPGRQCQKTTNECGAKQTYGVDCDENAACVDTPEGFQCVCQPGYADVSTSISKLPGRKCVESVNECTNGEADCSNNADCFDRADGYECKCRPGFVDASPNVDKYPGRVCNKPKAPEYYGQQSRQPQCSEGSGCGPNEECRFNTAGEKVCQCRRGSVQQSNGVCKVFSQCEQANECDRNAFCSNTYDGPKCQCKDGFLDVSPDPVRLPGRKCQQVRNECADGSHDCSHQAACQDTPTGYICSCNSNCIDVSSRYNLPPGRKCSVAANQCSDKSLNSCDENADCVQLPDGYTCKCFAGYVDVSSNANLPPGRVCTLSTACPAQPTDLVFLIDGSGSIGSYVFQTEVLRFLAEFTELFDIAPQKTRVSVVQYSDQIRHEFGLDNYSDRKSLQNAIRNIEYLTGLTRTGAAIEHVANEAFSERRGARPVGQVSRVAIVITDGRSQDNVTRPSDNARRQDIQLFAVGVTNHVLDAELEEISGSKDRTFHVSGFEDLNTRLRSAIQRVACPHQNNEDTYNKGPCDPSNHNGCDRSLNQVCQQKNGKFVCACPAGFDIHPVTKVCGGDICNPEIATSCPDPEICEKTPFGNWRCTCPADLGWRDRLTGVCKIGEKPVQTSESNDECSPNDVHSCPANSKCEKGAGGEFICKCDAGFQRNGRTNKCEAPGTCDPRMPDSCDARKKEKCLPDGRGAFACMCDRHHKRHPVTDICLIDECAAGVADCDPNAKCTDTDESYICTCNEGFLDKSPEQNKKPGRVCSKQRNECLDGTHNCSMNADCIDLPDGFLCRCKEDFVDISPNPNAFGGIDCRALVNECLITGGHNCHEHAICIDTRDSYKCQCKEGYVDHDELRNPGRTCKKLNQICESGKHECDKNARCVEKGANDYECVCNAGFIDKSPLTHRPGRKCVEPICSDDSKHDCHSAAICEENDSVPEKYTCKCRDGYLDVGAVMGGGKSGRECKELVNECLSASLNSCDAAATCIDLDDGYTCKCPLGSKDESPVPKLPGRSCKGLVNECNIPHLNNCSHFATCIDLEEGYECKCKPEYHDQKPEQPGTECKFIINECLAENLNDCSPNAMCIDKIDGYDCKCKAPFQDEMPSNPGRICRFDECADPKDNDCDKHALCIDTDDSYTCQCKEGFFDEISDPKKPGRVCIGLVIEPQNQSEDPTTPDPNTIKCGNGLCHLDLGEVCVGGATCSCRPGESRDNEKEKCVPTTSIPLVVRVMEYDGEPIQYRTDYSKPDTQAHIEIVDAVKKSVGKIIGKTDVAPRFVTTDVNYITNPKVQNSEWDKGLLGNVSVHLAGKEEVDKCRFYEQFAEIVREMGGRVDRIKLSDDADLDPCKKEEEKKGIPCGNTFCSIELGEECIAGKICGCPKGQKRKDANSPCRAVESWNLPLYVIRDGHEKITYSPSLSNPLNDDHKDLVSRFESGVAQSYDKTPLKGAFVTAEVNEIENPESRKKSWDTGILYNFTSHFVKGSVAEPASVFTDLIDYIQKRNDFEVGKSKLFISPEQLNPFSNCYHSDCHPDAICKEVGKGYTCTCPDGFRDLNPSRPGRNCLSYRGVNECEKPELNECSPHARCIDLDYLYKCECIRPYVNSAVGDALPGSVCSIDYCQDVNYCPLNSTCVNVDEQARCDCKPGFVDLRKSGHLSEAGLGESICRRQSDIDECALGLHNCSAAAICIDKKIGYECQCQEGYEDGNPSQPGRICAASLCGLCNGHGDCIHDALSSNVTCACLDGYTGQFCETAPSNLPLILMTLLALLFLLLTLLCCLYMCARCRCFGARGRSEGSASGQEILGSDYYTIPRAKLARPLYGDEMGDDHAGALAAYLDDGASISSDGSIEEIERRVTTDVTTREVRTTTVRDDDGNIISQSQTISHGNPHETDTEQYGMISSDHYKTSASEAMDAAMSTSASGAAYNQSSGAMMSSASGHKSAYNQGYASDSEDSDAGHAVYDRTTRTNQSHDFEPGADPRTGTERSKREFVTTTKAEEVNYF
The following text describes a protein:
Function:
The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i.e. under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, have been implicated in this activation process.
Sequence:
MLESCRNAQERWGGVHQLIDRWLHERQQLVQAFDALSGIQAPAPNAEELQHFCQLLLDYVSAGHFEVYEQLTAEGKAFGDQRGLELAKQIFPRLEAITESALNFNDRCDNGDCREGACLIAELKVLRQQLHERFELEDCLIEVLHNAHSQSGAEGSAVPV
The following text describes a protein:
Function:
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
Subcellular Localization:
Cytoplasm.
Sequence:
MLTALNRYWDYLRIERQMSPHTITNYQHQLDATIKILAQQDIHSWTQVTPSVVRFILAESKKQGLKEKSLALRLSALRRFLSFLVQQGELKVNPATGISAPKQGRHLPKNMDGEQVQQLLANDSKEPIDIRDRAILELMYSSGLRLSELQGLDLNSINTRVREVRVIGKGNKERVVPFGRYASHAIQEWLKVRALFNPKDEALFVSQLGNRISHRAIQKRLETWGIRQGLNSHLNPHKLRHSFATHMLEASSDLRAVQELLGHSNLSTTQIYTHLNFQHLAEVYDQAHPRAKRKK
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MLLPSSSSSYDPKGDSFGKSVDDSMRSTLTFGEKHSVFTSQNTDYGQPMACISYPFSDSGSGVWAAYGSQAMFHPLTAGGGSSATARVPLPLELAADEPIFVNPKQYNGILRRRQLRAKLEAQNKLTKNRKPYLHESRHLHAMKRARGSGGRFLNSKQLQQQQQSGSACTKAIADGANSLGSTYLRLGSGAAGDRPTSASKTISSQENNKRVAALAPAFTMIPAAQKDDDFFHHHGHHLSFSGHFGQSSERYT
The following text describes a protein:
Function:
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAETSSAKKPSLNDQERDLEQQAFIEFQKADYHACYQTLQKLLKTQDSNPKVLHNRAVVEFYNSDLRRYDQFRSAMIQQTGLVGEIRTVEVKDRESCAAYVNQAIVLYHFKQPLAALKIMLAVMAHFDRLDDYLLRRAGIFTVHLLLDTNQPKKANRLLGMLQNRLGIQVYAILSDSDEDEPLIDNESRKDISELQFEEFRKEFRLILIRSNLLNGKKNMSIPLEDTSEYSILKGHQYFLGNDYQMAAKELSKQFTNEPVSVNRHGEDQNTILANNMGVIHFSVKHYALAARFFQQALLFDKSATEDTSTERVEGSPLYCVGATKRPEILYNHGLALLHLQRPKEAFECMLIVLNSNHNNPRLWLRLAECCIMVHRQEKQTQNASICHGTVGCGVHRKYVLNPSPKTAVPEGDQSLAIPATTLEFGALCLRNAVALLEYHEPELIRQTESSDKTVAWDKVYEGVPCNPSLPMKLVSFNKLKCAVLAAYSYVLNTLGEYSLALKYAKQMLTMKDLPQSYLLLSHMYAAEALIMMNRPLEAITYLEPKFITELAGDDFGMRASPHWNINSADAARSVMHYNRAVVSFLIGDYEQAKIAMSSCNHPLVMPYLKMLNVYQELLLGNYDKVQLLIRYDTPHLI
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MEQLQHQQERAREVYRECLRNHAAKLGTYASDGCCEYTPDDSQPAALLCAACGCHRNFHRKAFLDGTASPGAASQHAPLMLPSPGAPPGYMHHHLAMAGPSGPGVAMGGGDGGGSHSGGGSRRRTRTKFTDEQKARMLRFAERLGWRMPKREPGRAPGDDEVARFCREIGVTRQVFKVWMHNHKAGVGGSGGAGAQTSSSTTRGGGGGGGGAGGMSPAMGGDGEDDEEVRGSEMCM
The following text describes a protein:
Function:
Cleaves polygalacturonate or partially methylated pectin. When assayed on polygalacturonate or on pectin, it releases monogalacturonate as the principal product.
Subcellular Localization:
Secreted.
Sequence:
MRNCKGLSILLCFLLVFFAMPFPAVAEEAEAMPVSEASEWSFSAFGSNTSVEKNPDPMINSDGSVKIVANGGKIASNEQGISFYYREVPSDANFEIKAKAEVLNFKGDDKQVSFGLMLMDQIGQHRNSEKHNSNYIAVGALDTIIKAFYMQESLTKTDMLSQTPSQGDIFELSIKKSGDNYVLTCNGTTETFTLPGLFSDTIYVGIYAARNAEIKFSDLNFTLDTKDIVDLSVDLSGMKTSYLVDEPLNLKGLKVTAHYSDGTSEELTEEDYIVTGFDSSTPGTNTICINVGEISKTIDLEILPLTCTKLTVKYLPAKTDYYLGDSFNPEGLKVIAEYNDGYKVTELTEDKYALYIAGKAAEDYVFSKAGTQKVEVISRENPSVKTGFEVNISDASIESLEISRKPEKTAYFIGDEPDLTGLVVYARYSDGSKVRLDKSEYEVKGFDSSAPGEKEITVYHKGKTVAFSVVVKEKEVMGIEVTKYPKTTYYIGETFNAEGLEVSKVYDNGDREPLTDFSVDASAFDGSTPGVYDVIISADGFDPITLKVTVREKTEYEWKAIRFGQSTSDSKNYVNFLDNGAVEIVALEGGGKIATDHDGITFYYTEIDAKDNFVLSADIKVKEYAKNPHDGQESFGIMARDAIGTPGDSSIFASNIAAIGGFSGGTKSPNGTQLFIRTGVSSPDGAGSKGIRRIMIKDEKPGPDNTYPAAEYRLTLAKTNSGFVGKLNDGEEVIFYEPDILNVQDSKIYVGFFAARLATIEVSNIELYVSSSETDAPRYIPPEAPVTPSLQILSLDKTSNVNYSLVVKPNVNGSITVKQGAEILVRDVTVNAGEKYSVDAVLEKNSENPFTVIFIPDDTQNLSSYEKIIKNFSVTMRTYNEGGNIYVSPNGTPYGDGTKDNPLDLDTAIAFVKEGQKIILMNGVYKRDSALVISRYNDGTAENRKYLVAEPGSRPVIDFDKKGQGVTLSGNYWYIEGIDFARSAPNYPGFIIGGNYNIVENCRFYENGDTGLQISRTDSSENIAEWPSYNKIINCESFDNRDPSENNADGFAAKLTCGVGNMFIGCVSHHNIDDGWDLYTKAGTGAIGPVIIDSCIAYENGTLTDGTVGKGDKNGFKLGGEGVPVQHIIKNSIAFNNGAVGFTSNSNPSVIAINNIAYNNAKGNLVFTSYSGIETHFVVDGFVSYNTEGAPRDSATGVPASDDNYLFDGTKSVNKSGEELTEKEFIERLLELISKIKSIK
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MIGADDAAFNDSSYTATDNVRRGLAVDTDNSDPFSDPATYTSGSSSRRMTRRRLLRALLDSQTASSNAVAFGSSRNHLNRPVDGSLLFLSARQIHRGIFTSDALMPAAGHSQRIESASEHHTHPSQADEYLDYNENLSVQSDLGTAAHSNASAPNQTRNRSGPLSHQLQSGQWMSMLQILGWLLIFRVNNALLVKTYFDPDEFWQSLEIRGFAHPLLFAAVYKILQVLSLDDTFFLTIAPRIVQGCIAAIGDFFTFLLAYRLFGMATAFWTIAAVLLSWFNYFCLVRTYSNSLEACLTSIALYYWPWSRDEVQGNRPTRRNFRISLIFAALSCIVRPTSAILWIFLGTSLLFRKSIRIYAVVNDVLITMIAAIGVSSAIDFQFYQTWTFTPYEFLKLNVLQNIAEFYGGHPFHWYFTQGIPVVLLTLLPITVWGVLHTQYPRERECFWMCLWTVFCLSLQKHKEFRFLMPILPPLLVYAGHGLRVIEASDYVTDLVANSTAGDAEDDADNDEEYNNLDIDDIVSLRRRRPFSHAARERQQQNQSQRRSLRHPKTRPAKWLWKVLAVVGITNIATAFYLSRSHQRGIMEVMNWLRIELHGGKVSDILFLMPCHSTPFYSYLHRNIPMRFITCEPPIGVENRKGYQDETDVLYNNPLYFFQTYFDPRVGAKLLGWANTTSTSDFTDYSESPITPNISELPFVRRIEPITDAFSFLKSQTRGKYIDVPGQGYQILQHKWSSHIIMFDNPKLFSVVSSVLQGSGYSICARFFNSHFHDDPKRTGDVIVLCRLFLKVLHASGHESFVLHATKYGRIFPAEL
The following text describes a protein:
Function:
Member of the two-component regulatory system TtrR/TtrS, which is required for synthesis of tetrathionate reductase. Positively regulates transcription of the ttrBCA operon. During mice infection, the ability to use tetrathionate as an electron acceptor is a growth advantage for S.typhimurium over the competing microbiota in the lumen of the inflamed gut.
Subcellular Localization:
Cytoplasm.
Sequence:
MATIHLLDDDTAVTNACAFLLESLGYDVKCWTQGADFLAQASLYQAGVVLLDMRMPVLDGQGVHDALRQCGSTLAVVFLTGHGDVPMAVEQMKRGAVDFLQKPVSVKPLQAALERALTVSSAAVARREIILCYQQLTPKERELASLVAKGFMNREIAEAMNIAVRTVEVHRARVMEKMQAGSLAELIRRFEKMASPETRIRTTYEP
The following text describes a protein:
Function:
Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the first mannose residues to the dolichol-linked oligosaccharide chain, to produce Man1GlcNAc(2)-PP-dolichol core oligosaccharide. Man1GlcNAc(2)-PP-dolichol is a substrate for ALG2, the following enzyme in the biosynthetic pathway.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MAAFCVALPAVAASLLLLLLVSWKRWRGARAKRHVLIVVLGDVGRSPRMQYHALSFVQSGFAVTLLGFCNSRPYEELLQNSRIQIVSLTELQKLPVGPYIFQYGLKVVFQSVHLLWKLICREPAAYIFLQNPPGLPAIAVCWFVGFLCGSKLIIDWHNYGYTIMGLVHGPSHCLVLLAKWYEKLCGRLSHLNLCVTNSMREDLAENWSIKAVTVYDKPASFFKETPLDLQHQLFMKLGCTYPAFKARLEPLDLATERSAFTERDAQSGVVTHLRGRPALLISSTSWTEDEDFSILLAALEKFEQLILDGESLPSLVCVITGKGPLKEYYCSLISQKRFQHIQVCTPWLEAEDYPLLLGSADLGVCLHKSSSGLDLPMKVVDMFGCCLPVCAVKFRSLQELVKHEENGLVFEDAEELAGQLQMLFSKFPDPAGKLNQFRKNLRESELLRWDESWKQTVLPLVMDT
The following text describes a protein:
Function:
Component of the SAC3-THP1 complex, which functions in transcription-coupled mRNA export from the nucleus to the cytoplasm. SAC3-THP1 functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket), by association with components of the nuclear mRNA export machinery (MEX67-MTR2 and SUB2) in the nucleoplasm and the nucleoporin NUP1 at the nuclear basket. THP1 binds to RNA in vitro.
Miscellaneous:
MISCELLANEOUS: Present with 1140 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus envelope. Note=Localizes to the nuclear pores.
Sequence:
MDMANQLLDELAHGNFSHLTLNLSQNGREIAILQKQLTGFDDKQLETFVEQHPAMPNDTRFKIMCTSFLNYARDVDPWSAWSSSDLIFEFYQCLINCLINDNAPHIEMLIPVATRETEFIINLAGKLDSFHLQLHTRSHQFLSHISSILSRLFNSIKPPRGNASSTNIPGKQRILLYLVNKLNNIYFRIESPQLCSNIFKNFQPKSMLAHFNEYQLDQQIEYRYLLGRYYLLNSQVHNAFVQFNEAFQSLLNLPLTNQAITRNGTRILNYMIPTGLILGKMVKWGPLRPFLSQETIDNWSVLYKHVRYGNIQGVSLWLRQNERHLCARQLLIVLLEKLPMVTYRNLIKTVIKSWTTEWGQNKLPYSLIERVLQLSIGPTFEDPGAQEITIYNGIHSPKNVENVLVTLINLGLLRANCFPQLQLCVVKKTTMIQEIVPPVNERITKMFPAHSHVLW