lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIIGVVSGQEPEEATPSLSARSTVRWRTFVRTETSSAVFLLAAVAAALVWANVGPHSYEAVWQARFTVGFDTRRLSLTVHEWINSGLMSLFFFVVGLEARRDFDMGELRDRRWLLLSAIAGLGSMIVPALIFVLVNAGRESVHGWGTAMSTDTAFALGVLAVFGSRLPASLRAFLLSVSVVDDLVALLVIAVFYSDEIRLPALLVAVCALLAIALLRLAGVRGALYCAVLSVVVWVALHEAGVDPVVAGLAVGVLVAAYPAPRGDLEQASRLFRLFREQPTPELHRSAVQGLDAAISPNERLEQRFLPWVSFGIVPLFALANAGIELSGPALADAFTSPVTLGIVLGCVVGKVIGTVGSMAAARLLSGGRLRPNVGWGSVTVGGAIAGSAFTVSLLIASLAFDGAELEEARIGILVTLVGAFLTSWAVTAVIGLLPERRRARALLGDVDPLTDLAVPVDRRHDRIRGPESAVVTVVEYGDFECPYCGQAEPVVRDLLGQESDVRYVWRHLPLRDVHPRAQLAAEASEAAARQDRFWEMHDLLLERQNALAAPDLLRYAGELGLDVERFRQDLRDHLGARRVAEDVDSADLSRVSGTPTFFINGRRHHGAYDIAALTRAVELARQRALTG
The following text describes a protein:
Function:
Probably involved in resistance to biotic and abiotic stresses.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MLARAPPPYFNFPARNNTICNRNEIVRLFRNGGGVVARGAGFTRRPLETSSSYDDSTDDGFVIISAADKENEFAPPPSSDLLSSIPSESARRNGSRSRGLTASFGRLKAQKVKALVGKVTQKKQHMSHNEEEDEDDASDENYSADEGFGSSSILDLMRKKLAMKAIPRSGKSAERNEVKRASKVRESRESRRDLDRLEGDDEDVDEVSNPDRFTDNQRAGSRSSYSKGGYAANSRGKGDRLSVARDLDSFEGHGRAIDEVSNPRKFNDNERAESRSSYSRDSSANSRGREDRRFVAKELDTFQGRDKAYDEVYNPRRFTDNERGLRGGSHSKGSDTNSRGWGDRRSVVYTRDMDDWRERNKTKDTRETGFFSRKTFAEIGCSEDMMKALKEQNFDRPAHIQAMAFSPVIDGKSCIIADQSGSGKTLAYLVPVIQRLREEELQGHSKSSPGCPRVIVLVPTAELASQVLANCRSISKSGVPFRSMVVTGGFRQRTQLENLEQGVDVLIATPGRFTYLMNEGILGLSNLRCAILDEVDILFGDDEFEAALQNLINSSPVTAQYLFVTATLPLEIYNKLVEVFPDCEVVMGPRVHRVSNALEEFLVDCSGDDNAEKTPETAFQNKKTALLQIMEENPVSKTIIFCNKIETCRKVENIFKRVDRKERQLHVLPFHAALSQESRLTNMQEFTSSQPEENSLFLVCTDRASRGIDFSGVDHVVLFDFPRDPSEYVRRVGRTARGARGKGKAFIFVVGKQVGLARRIIERNEKGHPVHDVPNAYEFTT
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum. Golgi apparatus.
Sequence:
MRLYFSAFRHPKRLGLCLLITLSIILLGWQCVLLYNHSPEIQRSVYTLTGLAPSSKMAFVTMLTVRAANGENEVENTQQDWYYNSTRLLVHRLVKFKPTKSKYPVVVLAMKGIDQWKLDQLQEDGAIVKVVDPLYAHEVVDDVNDIALLDSRWSMMFTKLRVFEMYEYDRICFLDSDILPIKKMDKVFDVHQLSYSKDSVLFPPTLFYKPRRSIFWRRFTEEFAAYGLTRDDLYPYVFAAVSDPGMWHETPPPFKDYFNAGLFVFKPLKAHYKRLMALARFPKLYDNANMMEQSLLNFAYNSAGAFPWESLDWTFNGLWARKNDLPYLKAVHGKHWQPEGSLGYDEDTSKLWWDAFQEMQTYHDQQRNADLY
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSLRKPAKSRKAMKGRKREVEGVIPITRFLINIDKLDSAPLYSPRTQRFVPIPSNLLNRHDFFLQSIRTSDAVETWANAFVALQRMANSSANGGHVDQSDHLALLPPNVRKKGRPTLVLDLDATLFYTSAELLNTPLDYFDMGEESTYRYLYLRPYALDFLGWASTVFEVIIWTAAMESYAEPRIRATEIDRYADVVLYRGACDMIDGSLVKNLAKLGRPLSDMIIVDDNPVSYALNVELAYPIPPFSGEEDDLELLRLVPILRKVLELSSLKRGIYKTIFSGSSMHRALETIGQYTYASGL
The following text describes a protein:
Function:
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
Subcellular Localization:
Secreted. Cytoplasmic granule. Note=Delivered into the target cell by perforin.
Sequence:
MNIPFPFSFPPAICLLLIPGVFPVSCEGIIGGNEVAPHTRRYMALIKGLKLCAGALIKENWVLTAAHCDLKGNPQVILGAHSTSHKEKLDQVFSIKKAIPYPCFDPQTFEGDLQLLQLEGKATMTKAVGILQLPRTEDDVKPHTKCHVAGWGSTKKDACQMSNALREANVTVIDRKICNDAQHYNFNPVIDLSMICAGGRKGEDDSCEGDSGSPLICDNVFRGVTSFGKCGNPQKPGIYILLTKKHLNWIKKTIAGAI
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly to 18S rRNA where it nucleates assembly of the head domain of the small subunit.
Subcellular Localization:
Mitochondrion.
Sequence:
MGDFDGEQKELIKKLVNFRMIDGKRTRVRAIVYKTFHRLARTERDVIKLMVDAVDNIKPICEVVKVGVAGTIYDVPGIVARDRQQTLAIRWILGAAFKRRISYRISLEKCSFAEILDAYRKRGISRKRRENLHGLASTNXXXXIHFFIYLMKFPFY
The following text describes a protein:
Function:
Cell surface receptor which may be involved in carbohydrate-mediated communication between cells in the germinal center. Binds glycans with terminal alpha-linked mannose or fucose residues.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Membrane; Single-pass type II membrane protein. Note=In fibroblasts, expressed on the cell surface.
Sequence:
MHNLYSITGYPDPPGTMEEEEEDDDYENSTPPYKDLPPKPGTMEEEEEDDDYENSTPPYKDLPPKPGTMEEEEEDDDYENSTPPYKDLPPKPGSSAPPRPPRAAKETEKPPLPCKPRNMTGLDLAAVTCPPPQLAVNLEPSPLQPSLAATPVPWLNQRSGGPGCCQKRWMVYLCLLVVTSLFLGCLGLTVTLIKYQELMEELRMLSFQQMTWRTNMTGMAGLAGLKHDIARVRADTNQSLVELWGLLDCRRITCPEGWLPFEGKCYYFSPSTKSWDEARMFCQENYSHLVIINSFAEHNFVAKAHGSPRVYWLGLNDRAQEGDWRWLDGSPVTLSFWEPEEPNNIHDEDCATMNKGGTWNDLSCYKTTYWICERKCSC
The following text describes a protein:
Function:
Required for the formation of pollen surface apertures, which arise by restriction of exine deposition at specific sites. The aperture length depends on the INP1 dosage. Does not play a role in specifying the number or position of apertures. Acts in a sporophytic manner.
Miscellaneous:
MISCELLANEOUS: The number and position of apertures is strongly correlated with pollen ploidy.
Subcellular Localization:
Cytoplasm. Note=Located at 3 equidistant spots close to the pollen equator. 3-D reconstruction demonstrates that INP1 is restricted not to just 3 spots, but to 3 long and narrow regions underlying the position of future apertures.
Sequence:
MPFSFFSRKKPSRRFNDFYEDWSKTLTENCLPLLRQSLSSAASASVLSSNVDLVLRHLVLYYETLDLAADHNTIPYLLFPSWRNSLETPFLFLGDIHPYLLTNLLRSFIDRENQDSDDEDEETSLDLVNQPLKMTMAWKDPSDELVKRIDQIECTMRLMVPGLMDRMRKTQRSFVARVSESWVSSYQVGKKKKLTATVATASTSVDEAAKIEMEELVSIFVDANRLRKSVIMDIVGATSEHQAALFLEGLCQFLAGFKDQILLQDFEILSLPN
The following text describes a protein:
Function:
May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MKLSYFYLLGLLLTSGQALMQVTISLSKVEISVGQSKYFTCTVIGEADNIDWFNPEGEKIISSQRVVVQREGIRSWLTIYKATVDDAGIYRCQAADSKGHSQEATVVLEIYQKLTLEDVLSPQEFRRGENAEVVCHVSSSPAPMVRWLNNREDVTDIDDRRFVMLPNNNLQIKNISKRDEGTYRCEGRVEVRGEIDFRDISVIVNVPPEILAQQRSFNATADRLEDITLHCRATGSPKPYITWHRNGKLVEENEKYDLREDNTELTVKQIISSDSGLYICRATNKAGFTEKQSFLQVFVQPHIVQLQNETTIEHGHVTLTCEAEGEPIPEITWKRSSDGMIFYDGDKSQDGRIESTGHRGKSSLQIKSIMLSDAGRYDCEAASRIGGHQKSMYLNIEYAPKFISNQTIYYSWENNPINISCDVTSNPPSSIYWSRDKLLLPARNLTNIKTYRDGKKILLEITPLSDNDFGRYNCTAINSIGSRIQEYILTLADVPSNPYGLRVIELSQTYAKVFFNKPDSHGGVPIHHYQMDFKEVSSEIWKVVRSHGTQTIIVLGNLEANTTYEVKVAAVNGKGKGEFSKTEIFQTLPVREPSPPSIHGQPGGGKSFKLSITKQDDGGAPILNYVVKYRSKDKEDQWLEKKFLGNKDYVVLDHLQWNVGYEAHIIATNRLGHSEPTVFEFVMPPKPNIIADTLFSGLGIGAVIGLAVAALLLVLVVTDVSCFFIRQCGLLMCITRRICGKKSGSSGKSKELEEGKAAYLKLLLKEENGKEALSAEAIEIKISNDIIQIKESDNKA
The following text describes a protein:
Function:
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Sequence:
MPEPSKAAGKKGVAAPKQAAKPAAKEAPKEAPKEAPKEAPPPQEAPQDTHDGELPPDDTKPEDRTPEITGLFIIKPVDLTVETGKDILLLASVDASQLSVKPNIKWFKGKWLELGSKSGTRFQFKETIDKEKKVYNFELKINKAAVADAGGYRCEVLSKDKCDSCTFNIEVEAAVKDEGNILQAFKRTGEGKKDEDAGELDFSGLLKKRVEDKQKEQKKKKEEDDCGIPPDVWELLKNAKPSDFERIAFENGITDLRGMLKRLKKVRKEAKKSEAFGKKLDTCYSVDKGNRIKMQVELTNPDIPVKWFKNGQEIKPSAKYVFENVGLKRVLTINKCTLADDAAYECVIGDEKCFTELFVKEPPVLITKALDDQQAFVGDKVELEVEVSEEGAQVIWMKDGVELTREETFKYRFKKDGKKHILMINEATQEDTGRYQVMTNGGKCEADLQVEEKQLEVLQGIADLTVKAAEQAVFKCEVSDEKVTGKWLRNGVEIKPSKRITMTHKGRIHKLIIDDVRPEDEADYTFVPDGYALTLSAKLNFLEIKIVYVPKQEPPRIHLDCSGGEHINTIVVVAGNKLRFDVPITGEPAPTVAWFRGDAEFSEMEGRVHIEIRNEMSSFIIEGAERSDEGSYNIVVTNPVGEDKATLIVKVVDVPDPPENVHITSVGEDWANVVWEPPNYDGGQPVTGYLIERKKKGSQRWMKMNFEIFNGTAFESTKMIEGVLYEIRVFAVNTIGISQQANTSNPFMPIAPTSEPLHLTVEDVTDTTCTLKWRPPDRIGAGGIDGYLIEYCREGSDEWIPSNKDLVERCGYTVKDLPTGEKISFRVRSVNIAGLSEPAYMSQSVTIREIVQQPKIRLPRQLRQTFIRKVGEQVNLVIPFQGKPRPVVTWTKEDKPLDPKQVSIRTSEVDTILFIRSAERSHSGKYELSVMIENMKDVASINIRIVEKPGPAQAVTVKEVWGFNALLEWQPPKDNGNSEITGYTIQKADKKTMEWFTVYEHNRQPRCTISDLIMGNEYYFRVYSENICGLSENAGVSKNTAYIQKTGLVYKPFDYKEHDNNMAPKFLTPLIDRTVVAGYSTALNCAVRGHPKPKVIWMKNKVEIRDDPKFLMKHNQGVLTLNIRKPSPFDGGTYTCKAVNELGEAEVVCKLEVRVPQ
The following text describes a protein:
Function:
Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MNRMKKIAAVHIASLLALVVSSLLLHGGNTQDTGEGLQDSKQTSGRHTGALTIVPNEEEEEDSKDNDGVVSVEVDEYDEEDLEVFYPTKEWQTIKQGQAIPAGLHVSIDLTTGEKRAKLMDNDDDHTTEDEDPASRYMKWTDGDRQGMVNTKNKYFTASELKEALKKFKADQDDVSEAGQQKLKDVKDQYRSYDELKEIFQQMRVDVETDTEIMQKLLLAYTEEGASDDMKLHVLTELEYHVHQIDNAQNLIELGGFQLVILALNDSNSDIRAEAARVLGAAVQSNPKVQIEALESGAVPTLIRLVASDSSIAVRKKSLYALSSLVRQFPLAQLRFLQQGGLSCLAQLFGDPNATTLRIKAVTLLHDLMVEQINAENLSPDNPTNVEKKKQYERVPLLQMMVEAGWCQLVPTLLDSPDHDTREKVLRAMITLFTPCRNDYKSAETEQYLSVLRGEYEELVVEEKQEDSGDDYFSVLLSLVEEISTKMSY
The following text describes a protein:
Function:
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
RESEIRHGRTAMLAVTGFIVQDFVRIPGDAYSFEAVPKTVGAHDALLEGPMHQLLLWISLWDIVITYPSIQATMKGEREPGDFGWKWLAPKDEATLKKYEMNELLNGRLAMMAVGGIATQSVMNDHGFPFL
The following text describes a protein:
Function:
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MCVCECKVLCLRCVVLLQTEVVRERVPTDTYTHNTVRDRVQSSIRVRPRCCPPAVPVCFQRCQKLPKRRANVTPPSMQSQEEAVEGTEGVHNKPAGGDPAPANPPSSNEFYFHLPARFPASHMMPIGIGVQGAVCSAVDIKTGRRLAVKKLSQPFQDVTFAKRAYRELKLMRLVDHPNIIKLLYAYTPQQTLDTFRDVYIFTELMDSSLQHVFGTKLDHERISFLVYQMLCGIRYLHSAGIIHRDLKPSNIVVRKNCTLKILDFGLARSIDTSFTMTQYVVTRHYRAPEIILNMEYDTKVDLWSIGCIMAELITGAVLFPGTDHVDQWMRIVETLGTPRPEFIARTTPGTQRYISNQPVVAGRPFGELFPDEVFEGMASPNVPQLTNDAARDFLRRMLAFDPMERISVDEALAHPYVSVWYYEEDVMRPPPKPYDHALDARNLTVEQWKRLLFEEIQDIQRTMSLDEAG
The following text describes a protein:
Function:
Heterochronic protein which acts downstream of let-7 in temporal patterning. Plays a role in the developmental timing of postembryonic hypodermal seam cell division and fusion events and adult alae production. Represses lin-29 during late larval stages, which prevents terminal differentiation of hypodermal seam cells and promotes their division. Involved in post-transcriptional gene regulation, uses two independent pathways. Has direct and specific RNA-binding activity and, depending on the location (5'UTR or 3'UTR) of the target site, triggers either mRNA decay or repression of translation. Degrades the mRNA of transcription factor dmd-3 to govern the timing and extent of male tail tip morphogenesis. Plays a role in the sexual maturation of the nervous system.
Subcellular Localization:
Cytoplasm. Cytoplasm, P-body.
Domain:
The NHL domain, containing the 6 NHL repeats, is necessary and sufficient to target RNA but not to repress mRNA. The minimal region needed to execute repression consists of the coiled coil domain and the Filamin repeat. The RING-type domain is dispensable for mRNA repression.
Sequence:
MATIVPCSLEKEEGAPSGPRRLQTEIDVDANDSGNELSMGGSSSEGDSMSHHRGEHSPNHHHQDNHLGSGPPPPQFTGSLFDTPPSMIQSPQQQPQFQFNTGFGLGLPQDSFRCSVCSKSSTIGVLPFVCAHKTCQSCYQMTPSSYDRRACKLCGAVSTATANFTSQMYLSPTLPSPPRGALMSDCSTPTMNNHINSSTPLHQPRAFSFSLSGMPGSPSPVMGARMPSSAGGLMMRPIGFPDSDSSLTSWSPLQQPSQLSINNLSSIGGHQQQSPMLMQNVFDSLAVNDDTPVFSPLSPTNTSMHMPPSLMASPDVPKHSATIAPPRNSMCSTPRLQLATPMSSQSQQTFPIPSPLGSQPQQQQPMGPIQCQGCESKISFAYCMQCQEALCIHCVQAHQRVRATKQHAFVELQQLMATLMSRAVQPQQAQQYTQNVGGSVRQALGSVGSGDVFFSGHVSGVENDSIGSGESSPRSSSVCGTHDSVIIGICENCPHSVLLCAICVAQHPGKHRVQPLGDIRVAVGEVVNESQLLQWQCEKTGDTIKQIIDGIVTNATTAENEIRAAFDTHVNALEERRKELLKRVETVKNLKLSVLISQAESLQSKQIDLQQAIQTATKLMDSSDCDEMVLRQVFEKLASCQMGNEGTEPNNNILNVLMLACQVNEDDRLKFTAPQDGILLNKARQFGNIESGPCAKNSSIVGDSFKKAIRERQTVIYVQLRDACGDLLSSSIAATQPTSQALLPHQEPHSHLEQAMPTSDVQAFVISPDGSTVEVTMTPRENGIVALSYYPSIEGSYTLNILVKGTPISGCPTTMDIRRGRNYDEIAAKGPILTFGKEGSGDGELCRPWGICVDQRGRVIVADRSNNRVQIFDKDGNFISKFGTSGNRPGQFDRPAGITTNSLNNIVVADKDNHRVQVFDENGMFLLKFGDRGRAVGYFNYPWGVATNSHNAIAVSDTRNHRVQIFTPQGQFVRKCGFDSAYFFKNLDSPRGLCYLPDGQLLITDFNNHRLAVLSPRNMSEMKVYGSEGDGDGMFVRPQGVVIDPEGHILVCDSRNNRVQVFASDDMRFIGSFGLGPVPNSGFQMPQELPAPYSSLGGPFGAPAFSSAPTPLTPSPRQLLDRPTDLAVGPDGRIYVVDFGNNCIRVF
The following text describes a protein:
Function:
Has a role in rRNA biogenesis, cell proliferation and tissue growth by contributing to the localization of nclb to the nucleolus.
Subcellular Localization:
Cytoplasm. Nucleus. Nucleus, nucleolus.
Sequence:
MKSKVDKPVTNGAPNATKTKAKEDRKRAKTQKSEADSQIPAKILKKSKKEKPAETEEKENTASNANLKVSQINKAVFVVFKKMQGSQLTKKMINSLITLLRDDTNAEQRTATTGYVLKRLIRSTGADDMKTVSLAASYIHCILNAVPAIDAFEVLETLKRDLAVGSQQRGKEDSLAAVGQLVTAFCILQTPQFAKAEPKLVTAVFQILAAQLKGREYLVSLCGDILAVSFKQLPAAIFEEYVWPLLQPELNKPLSGLKVNTCDVLLAVHLTFSSVLGRENILASLWPKKPVYTQLFDLYFSGSTIHSDGVYARLASFLVNGGKDMLAAWQQYIDSKQPLKLNAAKACAIQVLSHVLLNFKPREEQLILDIFTPTCVQFLLHECSSVKWDKGEGKKPSLKKLKEICFKFEGSLVLCYEKQFQNDDNKLHLLLKLLEHTLQLDSVISLPRFCQKLINQLSVESLHKLYDYYNNKLYSLEDEDRVSRVHCLNQMQLILNHSKLSQTAKWRQKQLNYLLLAGLFHLDASKKPCEAAQASAFSRQCAARCEEIFLGSLLHKCSGLPGLCQLLQKTLSYLNKELGQPDAESKLRSPRDESLQKAWKQVEKLLERPSKESDVVGQSFEALILFVSLALCTKIPPSITVLEDLIICRKNALQKSKEQVNEELKWQDVLTDALLQLLLQTGHFWREFVQLVATALIPHLEHGNLEQVLEVLNMNKNPLSKKSDGEEESDDELDKEESLKDSSDDSEDEDEDEEEDEGEDDAESHLAQIRESVRQALVNDGDADDDGASSVDWNDVDEEQGERLNAALERSFQMFRPKSRKAQEKERPTKSERIDSTNLLHFRIRALDLLELFITKKPTQSVILDVLHCVFQVYSHCAADSKLQSLREASLKLLKKILARNIELKENQSTAPILEAIEQLMSSGEEHSEEDQENGKQPASRQAKRDIIIWRDRCFAYLVSQASADGEPKKSAVWPLLVEFLELWVAKRRSRLSLASFEALFQSGQWQGVAPLAVVLASHLDVQKTRSFRRAQILKLLSEQGRRLEVAFKDNNSSSKKFEKQIARYVNQLETKASSSKELNLLLKILAQGGEKWQKLREQIQLVAKDLQPNKKVAKQKKQAAAKPMVVEDEEST
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MALCATTQRTIRIAATLRRVARPFATDAVVESDYKRGEIGKVSGIPEEHLSRKVIIYSPARTATQSGSGKLGKWKINFVSTLKWENPLMGWTSTGDPYANVGDSALAFDSEEAAKSFAERHGWDYKVKKPNTPLLKVKSYSDNFKWKGNPQPEN
The following text describes a protein:
Function:
SNARE required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Miscellaneous:
MISCELLANEOUS: Present with 937 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MAETSNDPFLSYVLSSKQLTNLNRLRRKAVTKQLGSSDDNKVSEEFLRYQHTYQREAFEYLQTKHDAHKIMESQYEQYQSSSKTRRYSIDLDSVDAVDTESQTEYPNEEFIDRNEDSEAVMELRKRLLGKGQNKGLGYETTKSVDRQIEDQDTLQQDLIQDMSKLVGSLKQGAVAFQSALDEDKQVLGAAEIGIQVASQGLMDVSGKLRKYDKSKLSYLFYITVFIFMILGLVFTFIIIQLFPAL
The following text describes a protein:
Function:
Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules. Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore.
Sequence:
MLLSPIEAQILSQYQLLAVQLNTLSSEVKQLNSTTNQNSRPSGKSSSSEDGVEATNSGSADKLLDNLRNLEMKIGLVYTLFKGAVYSLFLQYEEDQNLKNDEEQRRNDDSDEEPQNHHEIDAIEGENNDDMGDRMESQENHGH
The following text describes a protein:
Function:
Part of an import route for newly synthesized mitochondrial proteins termed the ER-SURF pathway (ER surface-mediated protein targeting), which retrieves mitochondrial precursor proteins from the ER surface and reroutes them to mitochondria for efficient mitochondrial import. Acts as a quality control factor in the ER, promoting the proteolytic degradation of nonproductive and extramitochondrial precursor proteins in the ER membrane thus removing them from the ER surface.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MKVVSLRRIYSSEIYKLPTTRLHMDTLYYYYFVSHLAAALFVDLPITEWLGGSLSCLSGLRRFYLSTYEDPILLIPAPWKTALFSSELFFQVPFFIWVSLRLRKKARDPVLWVAILIYGVHAFTTTWCCMFELFAEKKWMIMSFYFPYLAIPLWMAIDMGGRLVKSCHAAKSGPSSTITSKSD
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP120 is involved in nuclear poly(A)+ RNA and pre-ribosome export, in GSP1 nuclear import, in NPC assembly and distribution, as well as in nuclear envelope organization.
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Sequence:
MACLSRIDANLLQYYEKPEPNNTVDLYVSNNSNNNGLKEGDKSISTPVPQPYGSEYSNCLLLSNSEYICYHFSSRSTLLTFYPLSDAYHGKTINIHLPNASMNQRYTLTIQEVEQQLLVNVILKDGSFLTLQLPLSFLFSSANTLNGEWFHLQNPYDFTVRVPHFLFYVSPQFSVVFLEDGGLLGLKKVDGVHYEPLLFNDNSYLKSLTRFFSRSSKSDYDSVISCKLFHERYLIVLTQNCHLKIWDLTSFTLIQDYDMVSQSDSDPSHFRKVEAVGEYLSLYNNTLVTLLPLENGLFQMGTLLVDSSGILTYTFQNNIPTNLSASAIWSIVDLVLTRPLELNVEASYLNLIVLWKSGTASKLQILNVNDESFKNYEWIESVNKSLVDLQSEHDLDIVTKTGDVERGFCNLKSRYGTQIFERAQQILSENKIIMAHNEDEEYLANLETILRDVKTAFNEASSITLYGDEIILVNCFQPYNHSLYKLNTTVENWFYNMHSETDGSELFKYLRTLNGFASTLSNDVLRSISKKFLDIITGELPDSMTTVEKFTDIFKNCLENQFEITNLKILFDELNSFDIPVVLNDLINNQMKPGIFWKKDFISAIKFDGFTSIISLESLHQLLSIHYRITLQVLLTFVLFDLDTEIFGQHISTLLDLHYKQFLLLNLYRQDKCLLAEVLLKDSSEFSFGVKFFNYGQLIAYIDSLNSNVYNASITENSFFMTFFRSYIIENTSHKNIRFFLENVECPFYLRHNEVQEFMFAMTLFSCGNFDQSYEIFQLHDYPEAINDKLPTFLEDLKSENYHGDSIWKDLLCTFTVPYRHSAFYYQLSLLFDRNNSQEFALKCISKSAEYSLKEIQIEELQDFKEKQHIHYLNLLIHFRMFEEVLDVLRLGHECLSDTVRTNFLQLLLQEDIYSRDFFSTLLRLCNAHSDNGELYLRTVDIKIVDSILSQNLRSGDWECFKKLYCFRMLNKSERAAAEVLYQYILMQADLDVIRKRKCYLMVINVLSSFDSAYDQWILNGSKVVTLTDLRDELRGL
The following text describes a protein:
Function:
Required for photoreceptor cell function. The ninaC proteins combines putative serine/threonine-protein kinase and myosin activities. Essential for the expression and stability of the rtp protein in the photoreceptors. The rtp/ninaC complex is required for stability of inad and inac and the normal termination of phototransduction in the retina.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Membrane; Peripheral membrane protein. Cell projection, rhabdomere membrane; Peripheral membrane protein. Note=Localizes in the cytoplasm or punctate structures within the nuclei in the absence of rtp. Co-localizes with rtp in the rhabdomere membrane.
Sequence:
MMYLPYAQLPDPTDKFEIYEEIAQGVNAKVFRAKELDNDRIVALKIQHYDEEHQVSIEEEYRTLRDYCDHPNLPEFYGVYKLSKPNGPDEIWFVMEYCAGGTAVDMVNKLLKLDRRMREEHIAYIIRETCRAAIELNRNHVLHRDIRGDNILLTKNGRVKLCDFGLSRQVDSTLGKRGTCIGSPCWMAPEVVSAMESREPDITVRADVWALGITTIELADGKPPFADMHPTRAMFQIIRNPPPTLMRPTNWSQQINDFISESLEKNAENRPMMVEMVEHPFLTELIENEDEMRSDIAEMLELSRDVKTLYKEPELFVDRGYVKRFDEKPEKMYPEDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSIKAILMLVNAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATTDGTQHNFHIFYYFYDFINQQNQLKEYNLKADRNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREFENILRDIDFNHKQLETVRKVLAAILNIGNIRFRQNGKYAEVENTDIVSRIAELLRVDEKKFMWSLTNFIMVKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRINMNMSFPRAVFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTALDNLLTKPDGLFYIIDDASRSCQDQDLIMDRVSEKHSQFVKKHTATEISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEAVQHKDESERKSYALNTLSAGCISQVNNLRTLAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMTKDNCRLLFLRLKMEGWALGKTKVFLRYYNDEFLARLYELQVKKVIKVQSMMRALLARKRVKGGKVFKLGKKGPEHHDVAASKIQKAFRGFRDRVRLPPLVNEKSGQLNENTADFIRPFAKKWREKSIFQVLLHYRAARFQDFVNLSQQVHIYNQRMVAGLNKCTRAVPFERINMREVNSSQLGPLPVPIKKMPFRLDQIPFYDTQYMVDPANSISRQAFPNQLLTQHMEDDEPWDSPLQRNPSMTSCALTYNAYKKEQACQTNWDRMGESDNIYNQGYFRDPQQLRRNQMQMNMNAYNNAYNSYNSNYNNQNWGVHRSGSRRNSLKGYAAPPPPPPPMPSSNYYRNNPNQQQRNYQQRSSYPPSDPVRELQNMARNEGDNSEDPPFNFKAMLRKTNYPRGSETNTYDFNNRRGSDSGDQHTFQPPKLRSTGRRYQDDEGYNSSSGNYGVSRKFGQQQRAPTLRQSPASVGRSFEDSNARSFEEAGSYVEEEIAPGITLSGYAVDI
The following text describes a protein:
Function:
Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing OFP18 show small rosette size, late flowering, reduced fertilization and blunt-end siliques.
Subcellular Localization:
Nucleus.
Sequence:
MVRKMKLPFLNKNTSSSSFSSNSSSSSSSWPWPSSHQQNLKTISSKASFIVNKPKDVYEPEPPPRSFSSSPSSSSYSSFSSTSHAIENPPEIESIENVIKGLKSSKRLIFERRGTSNSILEEATKRDDHEEEEDGLMLLSLESNDPYTDFKNSMEKMVEVHVLHHDWISLEKLLFWFLKVNVKASHRYIFAAFVDLVLNLAVGPSKDVAGEPNSDVVVEDSLSSSWPVSLYSSSDENSSTSVRFLPETSIGEKGRDVCCLSSLFELEEKIKDNIDPNDYVSS
The following text describes a protein:
Function:
CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH).
Domain:
Cluster B is an all-cysteinyl-liganded 4Fe-4S cluster; cluster C is a mixed Ni-Fe-S cluster which is the active site of CO oxidation. Cluster D is also an all-cysteinyl-liganded 4Fe-4S cluster that bridges the two subunits of the CODH dimer.
Sequence:
MDKERISYHESVQKMYERIKKDNMTNVWDRYEAQGIGGVPDRRCTFCMAGARCDLCSNGPCRSDAAKDKRGVCGITADGMAMRMMLLRNVMGASTYHYHTDQTIRTLRETAKGKTPYSIREPEKLRTFAGRLGIETLGSDSEIALYLCEFVEKDFNRPAYEPSRIVEILAPPERKKRWEELDIFPGGIYGEMMLSTSSCLTNVDGYYASLALKAMRLGIAMAYQSQIVNEYCQDILFGIPKPHTMRVDLGVLDPEYVNVLPNGHEPFLGFAMVQLARKPEWQEKAKAAGAKGLRVIASIETGQEMIQRWEEDDAFYGFTGNWISQEAVLASGSVDLFAADMNCSLPVAPLYAEKYGFKLMPVSELIAFEDITERLNYNPVEAGRQAAKLLNMAVENFKNRKNSGEPVLNLPVKEAVVGFSTESILDALGGTLDPLLDAIKSGAIKGVVGMVSCTTLRDYGQDVHSVAVVKELIKRNILVLSLGCGNGAMQVAGLCSPETREFAGDSLKAVCEALGVPPVLSYGTCTDTGRLADFLGAISAVMGVPIPDLPIAAAAPEYMEQKATIDAIFALALGLYTYVNPVPTVTGAPDLVKLLTEDCREVTGGVLNVEKDAVKAVDGIEQHIMEKRKKLGI
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MHQQQHQERPREVYRECMRNHAAKLGTYASDGCCEYTPDDGQPAPMLCAACGCHRNFHRKTFLDAAAGAHGAMLPSPAGASPGYGSGTHHTATTAAGMGGDAGAHGSGGRRRTRTKFTEEQKECMARFAERLGWRMPKREPGRAPGDDEVGRFCREIGVTRQVFKVWMHNHKSGGGSGGAGAGAGGAAQTSSSTTRGGGSGAVGGGGSMSPAICADVEDDEEVMRGSGMCM
The following text describes a protein:
Function:
Role in flagellar biosynthesis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Sequence:
MFPLTTPFPTANDVAFFTLVMGRMAGIFAAIPIFGGRRVPTPIKALLVFAMTMVCFPIIKEKMPQLPTDVLSLGFLMVQEVLVGVSLGLLSLIIFAAVEFAGQIVSVQIGLTIVTEFDPSQGGQLSIMSIILEMLATLLFLSLGMHHIFIGALVQSYDVLPLGAWHMSGALLQFIVTTIGEVFVLAVRLAAPVMVTLLATSVMLGIMARSFPQMNVFFVSMPLNIGIGFIVLGLSLPLFLHTVQGHFGLLDEQLKTMMKLMGKG