The following text describes a protein:
Function:
Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MWVWTPQDRQCILTTLAQLLLDKDCTVLISRQLRPLLLDLLERNAEAIKAGGQVNHDLHERLCVSMSKLIGNHPDVLPFALRYFKDTSPVFQRLFLESSDANPVRYGRRRMKLRDLMEAAYKFLQQEQSVFRDLWDWSVCVPLLRSHDTLVRWYTANCLALVTCMNEEHKLSFLKKIFNSEELIHFRLRLLEEAQLQDLEKALVLANPDTPLWRKDKELQYSTGHLVSADLSSRVTAVCGVVLPGQLPAPEERGSSRSSSREQELTFRSYVLVDSVCKNLQTLAMAVASQNAVLLEGPIGCGKTSLVEHLAAMTGRRKPSQLLKVQLGDQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATKGHWILLEDIDYAPLDVVSVLIPLLENGELLIPGRGDCVKVAPGFQFFATRRLLSCGGNWYRPLNSHATLLDKYWTKIHLDNMDKAELNEVLQNRYPSLSAATDHLLDIYFQLIGEKHHCLSESSVGGEQAPGEVPEARQENKRLSLEGRELSLRDLLNWCNRIAHSFDSLSSSASLNIFQEALDCFTAMLSKQTSKLKMAEVIGSKLNISKKKVEFFCQLYKPEIVINELDVQVGRVRLLRKQSEAVHIQREKFTFAATRPSSVLIEQLAVCVSKGEPVLLVGETGTGKTSTVQYLAHITGHRLRVVNMNQQSDTADLLGGYKPVDHKLIWLPLREAFEELFVQTFSKKQNFTFLGHIQTCYRQKRWQDLLKLMQHVHKSAVNKAGAESEPGSLLKEKWEAFGLRLNHAQQQMKMTENALLFAFVEGTLAQAVKRGEWILLDEINLAAPETLECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRNRFTELYVEELESKEDLQILIVDYLKGLSVNKNTVQGIITFYTAVRKESGTKLVDGTGHRPHYSLRTLCRALRFAASNPCGNIQRSLYEGFCLGFLTQLDRASHPVVQKLICQHIVSGNIKSLLKQPIPEPKGGRLIQVEGYWISVGDKEPTIDETYILTSSVKLNLRDIVRVVSAGTYPVLIQGETSVGKTSLIRWLAAATGNHCVRINNHEHTDIQEYIGCYTSDSSGKLVFKEGVLIDAMRKGYWIILDELNLAPTDVLEALNRLLDDNRELLITETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLDLQSYRRGSSVFAGKQGFITLRDLFRWAERYRLAEQTEKEYDWLQHLANDGFMLLAGRVRKQEEVVVIQEVLEKHFKKKLCPQSLFSKENVLKLLSKLSTPMSTLESKFSHIVWTEGMRRLAMLVGRALQFSEPVLLVGDTGCGKTTICQVFAALANQKLYSVNCHLHMETSDFLGGLRPVRQKPNDKEEIDTSRLFEWHDGPLVLAMKEDGFFLLDEISLADDSVLERLNSVLEVEKTLLLAEKGNLEDKDNEVELLTAGKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTKREDLIQIISRNLHPGLSLGRTDHKGADIAEVMLDFIDWLTHQEFGRRCVVSIRDILSWVNFMNTMGEEAALKRQETISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLARRECLKFLIKKLSKIGRLTESQKNELKIYDRLKDKEFTGIDNLWGIHPFFIPRGPVLHRNNIADYALSAGTTAMNAQRLLRATKLNKPILLEGSPGVGKTSLVGALARASGNTLVRINLSEQTDITDLFGADLPVEGGKGGEFAWRDGPLLAALKAGHWVVLDELNLASQSVLEGLNACFDHRGEIYVPELGMSFQVQHEKTKIFGCQNPFRQGGGRKGLPRSFLNRFTQVFVDPLTVIDMEFIASTLFPAIDKNIVKKMVAFNNQIDHEVTVEKKWGQIGGPWEFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLVYGERMRTKEDKEKVIAVFKDVFNSNSNPYMGTRLLHITPYDVQLGYSVLSRGSYVPPPTCRPLSLLHQSLQSLESVMKCVQMSWMVILVGPASVGKTSLVQLLAHLTGHTLKIMAVNSAMDTTELLGGFEQVDLIRPWRQLLEKVEGTVRALVRDSLLVSADDAEVVLRAWSHFLLTYKPRCLGEGGKCVTMEIVNKLEAVLLLMQRLNNKINSYSKAEFAKFVEEFRSFGVKLMQSASGHSRGTFEWVDSMLVQALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTVSERGMIDGSTPTVTPHPNFRLFLSMDPVHGEISRAMRNRGLEIYISGDGDGSIPDDLDLKVLLHSLGLVGDSVCDTLLALHSETRSAVVASPASSVSNLIQTASLIVQYLQRGLSLDSAFSKACWEAYVRSQASPANQQLVQALLEKHVSSLQAHETWGSSLLALGLWPDSLPSAVFTTEDSHLSKVRGDGQILAYCLNRLSMKTSNWARIQPLTLADLEKIMQSSHPENLKFTSVEVDTYWLDEPDALAVAVKLLIERATNQDWMLRVKWLYHLAKNMPQGLESIKIHLEASAAALRNFYSNSLSSGVSNVIKILQPNVTDESMIPLDPRWNMQAMDIIRNAMDFDPQTDQPEQLFALLESVANKTIIYFDREKRIFTEANLVSIGGKKLRNSVLRLSFEFHKDPESYHSLPHEIVVNLAAFFELCDALIGLWVQSSQGMVSDAGVNEILSSVRWRDRFWTVADTVKVDASGLALLALHWHWVLKHLVCRIPQLLMNHEDKYYREVQTVSEHIQNCLESPTGGFAGVKKLQKFLGRPFPFKDELVVECFSQLKVFNKALTIREWMPALGESGWQEDISRLQVVASEGTLKKSLLQAWGLVLRANVLEDVDSDALKNLVNAQHLELKARGISLGFLEKKHSEASFLLQPDFSTLIQLTRSVQLWPVMEYLAVLWQYKVTADFMTQACLRRSSKHQQPQIDEEISRHITFCLKHTPVAPQELRDFWSLVHHPEMTAEERISLWSELFNSTFTSFWSSTVTTHPEYWLTWNPLPGEQQRETPRSLLDPTLKGPGSLSRAVFSKCCIEIVTSSCRASPWDVSGLPILSSSHVTLGEWVERCQQLRDVSSMLWTNMAVPVVAEFRRTDAQLQGLVLCRHLAGLAELLPEPRQQEHVHNCRQLLLRDSQAFQHVGETLGDLARQEALPKELLCLLLTSLRHLFGEVEGKGDLPEPARRGSLWVSLGLLQIQTWLPQARFDPAVKREYKLKYAKEELHQLQCEWKTRNLSFQLQTGRDLEDEVILSHSHPHIRLLRQRIDQLENLICSLSKKQACRPPLPTYEALVQEIHHYVSSIAQATTVQDLLTRLLQALRSDGPRAAQVAQNLLKEEASWQQSHHQFRRRLAEEFALYPDATAPLQASILQLQHGMRLVAGEVHASLQGGLAGADRLGALATSLLAFPSVGPAFPTYYAHADALCSVKSEEVLRGLSKLILKRSGGRELEEKGQSPCTSREQLLLNALLYLRSHVLCKGELDQRALQLFRHACQEIINEWDEQERIAQEKAEQESSLYRYRGRTPRTALSEEEEEERAFRSQFPLHEKDFADILVEPTLEEKGPSGGQEEEATPGPAVLSQSSMQAVMRIHQQLCLGFARSLWYQQSPPPHGTEHYLSLFLSCYQTGASLVTHFYPLMGVELNDQLLGSQLLACTLSHNTLFGEVTSDLMVKPDGPYDFYHHPNIPEARHCQPVLQGFSEAVHRLLQDWPEHPALEQLLVVMDRICSFPLSSPISKFLNGLEILLAKAQDWEENASRALSLRKHLDLVSQLIIRWRKLELNCWSMSLDNTMKRHTEKSTKHWFSIYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHIRLQMLLVFHCHVLLMPQVEGKDALCSVLWNLYHYYKQFFNRVQAKIVELRSPLEKELKEFVKISKWNDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCRSSLAEGDEEEQPDSLPRPTGAAASKESPIQRLNRVLRETLLARPAAVQGAVPEQCLGAPLPSEGALLRRLPKLLKRMRKMCLTLIQGSPLPCLVEGLDQFTGDVISFMSELQSLKVDPSAEKEKQRSEAKHILMQKQRALADLFKHLTKTGLSYRKGLSWARTKNPQEMLHLHPLDLQSALSIVSSTQGADSRLLTEISSSWEGCQKYFYRSLARHVRLIAVLAAPAKEVGAGHVERCKGFSAHLMKVLIRQRRSLTVLTEQWILLRNLLSCVQEMDGRLTGPPVYPVAFPPQDGVQQWTERLQHLAMQTQVLLEQLSWLLQCCPAVGPAPGHAPYLEDPERLQGLLSPAARDLIPSDLTFPSPAPETQLPSGCLMRKQDPRWQQSTVRLTEMLKTVKTVKADVDRIRQQSCEALFHSWKDFEVCSSGLSCLSKVSAHLQGLESLFILPGVEGEQTDPQMALVESMEYVRREINKATDDFTTWKTHLLTPGNQEGNQMLDEGFVEDFSEQTETAIRAILCAIQNLAERNSKKTEESTDQARPQEEDETAGFESLQLGHLTKLLEEDFWADVSTLHVQRIISAVSELVERLKSSGEDGTAAKHTFFTQSCCLLVRLVPVLSRYSDLVLFFLTMSLATHRSTAKLLSVLAQIFTELAQKGFCLPKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIENEEQAEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSETGDLDKQMGDLNGEEADKLDERLWGDDDDEEDEEEDSKTEETGPGMDEEDSELVAKDDNLDAGKSNREKTRQDKKEEKEEAEADDDGRGQDKINEQIDEREYDENEVDPYHGNEEKLPEPEALDLPDDLNLDSEDKDGDGDTDHEDGEEENPLEIKEQPKDTEEAGHEAEDINEETEADQDEGQAQPQPEGGHSEDDKGEEGEEEMDTGADDGDQDAAEHPEEDTEEAPLSSEDKDKDTSEESPEKDTPLDQGLQPQTQEKEEGESSDMEEPVPEPTERKEHESCGQTGLESVQSEQAVELAGAAPEKEQGREEHGSGAADANQAEGHESSFMARMASQKHTRKNTQSFKRKPGQADNERSLGDHSERVHKRLRTMDTESRAEQDPAQPQAQAEDAEAFEHIKQGSEPYDAQTYDVASTEQQQSAKDSSKAHEEEEVEDTSVDPEEQEELRAVDTEPLKPEEVKSGSTAQPGSEEMEMETQTVKTEEDQHPRTDPSHEETENEKPERSRDSTIHTAHQLLVDTIFQPFLKDVNELRQELERQLETWQPHESGNPEEEKAAAEMWQSYLVLTAPLSQQLCEQLRLILEPTQAAKLKGDYRTGKRLNMRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFSDYSGSQILRLCKFQQKKTKIAQFLESVANMFAAAQQLSQNVSPEIAQLLLVVSDGRGLFLEGKDRVLAAVQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPFYIILRDVNALPETLSDALRQWFELVTASDHA