lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Monoglycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Note=Mainly present in locomotory and oral cilia.
Sequence:
MFQQNQQSQNQQAQNLMHIQLNGNTQLGLGALQTINVKPIKLQSRAQSLNPNLRISERNKQTTQTSSNRQNISNKSPNNLQTSKSGGLQTQNANQKLSSSSAPKKISGNFSSRVIYRAKTKNEDEIIKKQSSQTSISTNGQEKKGEIIRFATESQINNENSTPNSKIQLPPIQEKNSYKFYINSQSSNNQVSQDQSPPLQGLQAFNINKNKENQFTKKRHFDFLERTKVKNQSEETDLLKMHRYFRCKVSNLITGSGKKQYYLQYLKDMKDLMTKVKQYERVAKQNLFINDVMNKLKKIVATRAKYKYKEKIDFTRSIIMRTLGYESRQIIQQLKENMALEEQEYEDLEDDADREYEELKKKQEQQALDKNQKKELISSEIIANWKKMRGYQPNQKVFICIGQYTDLKNYLKEQGWIENPNPESLVFDLKWVTKKKDVDKDLLLDQQITNHFQKNHNLTSKNGIALNLRNLIWYDSVDIDTFYPRCFDLSDVQEFEDFIEEFKFTQAESILKQYVENKLVIDQKAKQYEKYLRLKILLACVALKRRTFSIEKKISLISVNTLPIISPEEWSVLNRQDNNYLFLEQNPDVYHRLSQIITREMDSEESNAVDLSKLAQKYLEASKEYDPQYDLNEKNLWIVKPAGLSRGRGIRAFDQLEPLLNYIMGKDVMWVAQKYMENPLTIHKKKFDIRQWVLVTEWNPLTIYFYDTCYIRICFDEYDPSDLQNKFAHLANNCISKHADNFEEKVNDTMMYLEDFVEYIKKIEGKDMFYSKIQKEMMNIAINSIKSCKDSIEPRRNSLELYGYDFMVDQNYNTWLLEINSSPSMEYSTPVTTKLVKMGLEDTAKVIHHHFVEGEKRFNKNIEYGLWKNIYREQK
The following text describes a protein:
Function:
Catalytic subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTSTIQLLQSHPFLLGLALRLSLLFLLPLLLDDNPLLRGVRYTDIDYDVFTDAAFHVADGRSPYERHTYRYTPFLASLLIGTLLSAKYFGKILFCVADAICGYIIVVLRKQRRRRISEEDDDERQYKQNNNNNVSGWRRLLDISPGLKDSLWWLYNPLPINICTRGSAESLVVLLPVLATSSWRLRRWGTTIPIIARACLAGIMHGVGIHAKLYPVIYTISFMAYFSHWNNNNNNNNEYKLLLTMLPNELQTYQRRDGLILFLVFTVGTVGALTHAAVHFHGREALEEGLLYHFQRVDHRHNYSMYWYWIYLARGRSYANANELSAVASPSSSIWGHLPLIPQVLILGFSSLGIAPYDLTFALFCQTFAFVAFNKVMTAQYFTWYLCLLPLCSDRIKWNSRRMAFSLGLLAISIIAWLLSAFSLEMLGWRSHRQVWLASLFFFVANVNLLTSILDGYKHEQIARAKTRPGEGWSKPKAKVT
The following text describes a protein:
Function:
Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.
Subcellular Localization:
Cytoplasm.
Sequence:
MSQTAPSDTEYNQRLERWSERLKSQTISHLPTDYSRPVPSRLVEAVFERTLPEDAKTALIKVYVAAQAKGILVTPFNILLTIFIILVSRMTGDEDISIGTSSENAIPFVLRTFIQPSDSFLDLLAKVCDLEKEGSSDAVDFSDLINFLNAKLSKKDDPRKTLVHLRFYNAPDAPSENFLSTTGLDVDLTVLVSVKKPSDQLTSLRSQFTFPDLQLKLIYNQLLFSESRVNIVADQLLKLVVSASKDVTGPIGALDLMTPTQMNVLPDPTVDLDWSGYRGAIQDIFASNAAKFPDRECIVVTPSVTIDAPVTSYTYRQIDESSNILAHHLVKNGIERGDVVMVYAYRGVDLVVAVMGVLKAGATFSVIDPAYPPARQIIYLSVAKPRALVVLEDAGVLSPTVVEYVEKSLELKTYVPALKLAKDGSLTGGSVSKGADDILQHVLHLKSEQTGVVVGPDSTPTLSFTSGSEGIPKGVKGRHFSLAYYFDWMAQEFNLSESDRFTMLSGIAHDPIQRDIFTPLFLGASLIVPTAEDIGTPGQLAQWANKYKVTVTHLTPAMGQLLAAQADEPIPSLHHAFFVGDILTKRDCLRLQVLANNVNVVNMYGTTETQRSVSYFVVPARSQDQTFLESQKDVIPAGRGMKNVQLLVINRFDTNKICGIGEVGEIYLRAGGLAEGYLGNDELTSKKFLKSWFADPSKFVDRTPENAPWKPYWFGIRDRMYRSGDLGRYLPTGNVECSGRADDQIKIRGFRIELGEINTHLSRHPNVRENITLVRRDKDEEPTLVAYIVPQGLNKDDFDSATESEDIVVNGLKKYRKLIHDIREYLKTKLPSYAIPSVIVPLHKMPLNPNGKIDKPALPFPDTSQLAAASRSHSKHGVDETLTATERDIRDIWLRIIPHATDVNKKASFFDIGGHSILATRLIFELRKKFAVNVPLGLVFSEPTIEGLAKEIERMKSGEMISVMDIGKEETREPEIEYGKDALDLVDLIPKEFPTSKDLGIDEPKTVFLTGANGYLGVFILRDLMTRSSNLKVIALVRASSEEHGLKRLKDSCTAYGVWDESWAQKISVVNGDLALENWGIEERKWNKLTEVVDYVIHNGALVHWVYPYSKLRGPNVMGTITALKLCSLGKGKSLSFVSSTSTVDTEYYVNLSNEITSKGGNGIPESDPLQGSSKDLHTGYGQSKWVSEYLVRQAGLRGLRGVVVRPGYILGDSKSGAINTDDFLVRMVKGCIELGLYPNINNTVNMVPADHVARVVTASAFHPEQGVIVAHVTSHPRLRFNQFLGTLSTFGFNTKLSEYVNWRIALERFVINESHDSALYPLLHFVLDNLPANTKAPELDDTNTREILKRDASWTNVDVSNGAAILEHEMGLYLSYLVAIGFLPKPTLEGKKLPEVKINEATLEKLASAGGRGGAPTH
The following text describes a protein:
Function:
Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression.
Subcellular Localization:
Nucleus.
Sequence:
MAAAESRALQFAEGAAFPGYRAPHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDPGPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQLLFSPLFQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVNCLPEPNGVGGGISDSSSQGQNFETCSPLSEDIGSKLDSWEEHIFSAFGNF
The following text describes a protein:
Function:
Efflux system for nickel and cobalt.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIAIKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIISTAFWMFWRTWRGERNWLENMHGHDYEHHHHDHEHHHDHGHHHHHEHGEYQDAHARAHANDIKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSIGLALTLVTVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR
The following text describes a protein:
Function:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MADSNLPPSSSAAPDPEPGITEQPGPRSPPPSPPGLEEPLDGTNPDVPHPDLAPVAFFCLRQTTSPRNWCIKMVCNPWFECVSMLVILLNCVTLGMYQPCDDMECLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFLEENFTIQGDVALPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKEQGRECCLSKDDMYDFGAGRQDLNASGLCVNWNRYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHRLMLEQRQRYLSSSTVASYAEPGDCYEEIFQYVCHILRKAKRRALGLYQALQNRRQATGPGTPAPAKPGPHAKEPSHCKLCPRHSPLDTTPHTLVQPISAILASDPSSCPRCQHEAGRRPSGLGSTDSGQEGSGSGGSAEAEANGDGPQSSEDGVSSGLGKEEEQEDGAARLCGDVWRETRAKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIVGQADGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTTPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSYSDEDQSSSNLEELDKLPEGLDSSRDLKLCPIPMTPNGHLDPSLPLGGHLGPAGAMGAAPRLSLQPDPVLVALESRKSSVMSLGRMSYDQRSLSSSRSSYYGPWGRSGTWASRRSSWNSLKHKPPSAEHESLLSGERGGSCVRACEGAREDAPPRAAPLHAPHTHHAHHGPHLAHRHRHHRRTLSLDTRDSVDLAELVPVVGAHSRAAWRAAGQAPGHEDCNGRMPNIAKDVFTKMDDRRDRGEDEEEIDYTLCFRVRKMIDVYKPDWCEVREDWSVYLFSPENKFRILCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSVASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDTRNITNRSDCVAANYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCPTRLLIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCTHDERSCLSSLQFVSPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEMAHGLGPGPGPCPCPCPCPCPCPCPGPRMPTSSPGAPGRGSGGAGVGGDTESHLCRHCYSPAQETLWLDSVSLIIKDSLEGELTIIDNLSGSIFHHYSSPAGCDKCHHDKQETGPRPSCWGMT
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Cytoplasm. Nucleus membrane; Multi-pass membrane protein.
Sequence:
MTVGTLSVVSSTASDTASHVSDTRKRQYQRDEALRKKIISELGKKSGNFESPVRKIRRNGEPGTVDSAALDPALTVHMQSLVTETAQLMAAKRQNCVLVVDDDEQLAGIVTATDIATRCVGAGLNARQTLIADIMSTSPLCITSDTRFDDALLLMIEHKFRHLPVVSDGGPDGSAGDEGDVIGIINMRACLREPLNRIARQQEAAQKLVEALEGAQEEIENKSVSGNTNSSSVSGNHAAEFLEYVESLKKKASGLEIMSLIDSSEEPFLVGTRTTVAEATESMARSGVSAVLVMDNGAVSGVFTAHDVVLRVLAAGLDPYRSSVIRVMTPHPDCALASLRVSTALERMIEGKFSNLPVVDESDAIIGMLSLFHLATAIEQTPEEEEEVFDQAENDAGIEPSNGFEDQQQQLLGNSNEVVENYDVNPPLPLNPLPSNTQQSESTYEYSARQLPKPPVQAWQNENLSSNNKPQEYVGVENDYNFSNNPPTAMSEQSFHPSVSQKPMDTPENGSNSFAASPYLQPYNSASQLAPSYVGSLPQYHGNPSFVEQALQDLVQPTDSASQIFPLNPQSPSQFTIKYRSIAGRVHRLRLDGINSVSDLRTAVEEREKEQLVTLTYIDDEGDVVELVSDSDLREAILLARRRGLPRLEVRGVAAFTNHLESSHPPISTVDSSIGSASVVEKGVANSIVDIHQPTAKADKGNSKKPIYIGIVSSSIVILAVSMWYLRRKR
The following text describes a protein:
Function:
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.
Sequence:
MAHQTLQQCFNVVPGKITCLQTRKEIITGEVFIVQSHGQSSCWISASVQLYSSTRLDPNTGKGKLSEKAYLKHGKCSEHNGTKITKYKVKFRVEPDFGIPGAFLIKNEHKHKFFLQSATLEVPANQSIQFNCKSWIYPFTKTKTNRLFFSNTVYLPNETPEALDELRKEELESLRGHGTGERKEWDRVYEYDYYNDLGNPDKGQEHVRPILGGSDSYPYPRRGRTGRPRCNQDPLTESRPTKFNLDIYVPPDERFSPKKLSEFIENSVQAIVHFPLPEAQSIDEQESNSFESLEEIKDIFSRHKRQGVEGWIAEKLKSLVSDDLFKEIKEASKKDPIKFPLPKIIEENELAWKDDEEFARQMLSGVNPTVIKGLEMLCHVFYRLNTHAVVEPFIIATRRQLSVMHPVHRLLDPHFKDTMHINALSRSIIINSGGILEKILFTQEISMELSSAIYRDWRFDEQGLPADLIKRYFSLSN
The following text describes a protein:
Function:
Activates lipidic moieties required for mycobactin biosynthesis. Converts medium- to long-chain aliphatic fatty acids into acyl adenylate, which is further transferred on to the phosphopantetheine arm of the carrier protein MbtL; May play a role in virulence by supporting bacterial growth in the liver.
Sequence:
MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD
The following text describes a protein:
Function:
Required for initiation and continuation of postembryonic mitotic cell divisions of gonadal cells Z1 and Z4. Zygotic expression is necessary for hermaphrodite fertility. May be a cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MMSDDMLDENDENFACQDVDEIIIYVPEFAGYREVNIDTAVSVCPTPIQQARRESSCRNLEMRRRFEKLRREKKEEKKLLADDEKDFDEDDDVFEDGEGLQMRTFQPNASIRDENGSMPSLLPRTAPIKKTRKHRRRRSGSFTGGVYPRKGHRNRSLLGHAIPPPNVHSADWRDMLAITDNKDDKLMKTLGVTRYLQSKGGDQVPPTSTTTGGAGGDGNAVPTTSQAQAQTFNSGRQTTGMSSGDRLNEDVSATANSAQLVLPTPLFNQMRFTESNMSLNRHNWVRETFTRRECSRFIASSRDLHKCGCGRTRDAHRNIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGGPHPYKAQYVRVNFDTEPAYIMSLFEHVWQISPPRLIITVHGGTSNFDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQSAQRNKIVCIGIAPWGLLKKREDFIGQDKTVPYYPSSSKGRFTGLNNRHSYFLLVDNGTVGRYGAEVILRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFAHQNVTEDGLLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQHKNLLTIFRLGEQGEHDVDHAILTALLKGQNLSAADQLALALAWNRVDIARSDVFAMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELYNTDKGPPNTLFYIVRDVVRVRQGYRFKLPDIGLVIEKLMGNSYQCSYTTSEFRDKYKQRMKRVKHAQKKAMGVFSSRPSRTGSGIASRQSTEGMGGVGGGSSVAGVFGNSFGNQDPPLDPHVNRSALSGSRALSNHILWRSAFRGNFPANPMRPPNLGDSRDCGSEFDEELSLTSASDGSQTEPDFRYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICPPFIQMLEFKTREELLNQPQTAAEHQNDMNYSSSSSSSSSSSSSSSSSDSSSFEDDDDENNAHNHDQKRTRKTSQGSAQSLNITSLFHSRRRKAKKNEKCDRETDASACEAGNRQIQNGGLTAEYGTFGESNGVSPPPPYMRANSRSRYNNRSDMSKTSSVIFGSDPNLSKLQKSNITSTDRPNPMEQFQGTRKIKMRRRFYEFYSAPISTFWSWTISFILFITFFTYTLLVKTPPRPTVIEYILIAYVAAFGLEQVRKIIMSDAKPFYEKIRTYVCSFWNCVTILAIIFYIVGFFMRCFGSVAYGRVILACDSVLWTMKLLDYMSVHPKLGPYVTMAGKMIQNMSYIIVMLVVTLLSFGLARQSITYPDETWHWILVRNIFLKPYFMLYGEVYADEIDTCGDEAWDQHLENGGPVILGNGTTGLSCVPGYWIPPLLMTFFLLIANILLMSMLIAIFNHIFDATDEMSQQIWLFQRYKQVMEYESTPFLPPPLTPLYHGVLILQFVRTRLSCSKSQERNPMFDFSLKLFLDNDQIEKLHDFEEDCMEDLARQKLNEKNTSNEQRILRADIRTDQILNRLIDLQAKESMGRDVINDVESRLASVEKAQNEILECVRALLNQNNAPTAIGRCFSPSPDPLVETANGTPGPLLLKLPGTDPILEEKDHDSGENSNSLPPGRIRRNRTATICGGYVSEERNMMLLSPKPSDVSGIPQQRLMSVTSMDPLPLPLAKLSTMSIRRRHEEYTSITDSIAIRHPERRIRNNRSNSSEHDESAVDSEGGGNVTSSPRKRSTRDLRMTPSSQVEESTSRDQIFEIDHPEHEEDEAQADCELTDVITEEEDEEEDDEEDDSHERHHIHPRRKSSRQNRQPSHTLETDLSEGEEVDPLDVLKMKELPIIHQILNEEEQAGAPHSTPVIASPSSSRADLTSQKCSDV
The following text describes a protein:
Function:
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MAYDGYSGGADDLSTYSSFDDSARFDSSRLDSARFDSSFRAPDDYKPDHFGMDDNREGFDDFKGASHGYDHPAPIYENEESAPGMPGMYGFGMPGSESPSGFPKGEYSAPGFTDAEYTSNPAGGSYNKELDEDLFGGDNGGGPMLPPPEEMQEEGAILRQWKRENMQRLQEKERVEKEKLQQIMDDADEYKEKHKAKRESNREAKMKENREKEMVYHADQEHFHKTADKQYWKAVTELVPKELPASLEPKSRQMKEKKEKKSTFVALPGPKPGRATDLGRFRQVLLKLKHNPPAHMIPPPPPPAKAEVKEGEKGAKDGAAKEGEKEKENGAAVAAPAADAAKAPEAPAAQPEPELIAAA
The following text describes a protein:
Function:
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
Subcellular Localization:
Cytoplasm.
Sequence:
MTHTNGFDALHAHAQRLRGAAIPALLAAEPQRPTQYARQVGPLYFNFARQKYDRAALDALFAIARERDLAGAFQRLFRGEQVNVTEQRAALHTALRGDLTDAPVASDAYATAAEVRQRVGALIQQLEGTDVTDIVSVGIGGSDLGPRLVADALRAPSGARFRVHFVSNVDGAAMQRTLATLDPARTAGILISKTFGTQETLLNGSILHAWLGGSERLYAVSANPERAAKAFDIAPGRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLDGAAQFDAHVLNTPLEENVAVLHGLTAVWNRNLLGSATHAVMTYDQRLALLPAYLQQLVMESLGKRVKLDGAAVDSDTVAVWWGGAGTDVQHSFFQALHQGTSVVPADFIGTVHNDDPYAENHVALMANVLAQTEALANGQDSSDPHRSYPGGRPSTVILLDALTPQALGALISMYEHSVYVQSVMWGINAFDQFGVELGKQLASQLLPALKGEAADVADPVTRELLAKLRG
The following text describes a protein:
Function:
Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity).
Subcellular Localization:
Cytoplasm. Cell junction. Note=Localized at cell borders in single layered keratinocytes. Localized at cell borders in the basal and spinous layers but is more diffusely localized in the granular layer. Colocalized with actin near the cell membrane, especially in cellular protrusions (By similarity).
Sequence:
MPRPGQPRPSSGPPRLGPWERPTELCLETNDERSQPPPGRRTRRPDPKDPGHHGPESITFISGSAEPANEPPTCCLLWRPWGWDWCRAAFCFRRCRDCLQRCGACVRSCSPCLSAGDPIEGSSEAAWAKEHNGVPPSPDRAPPSRRDGQKLKTSMGSSFSYPDVKLKGIPVYPYRHATSPVPDADSCCKEPLADPPPTRHSLPSTFTSSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRSRPQTSEGRSARSTAPAAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGAPGYPASQDSSFQGTDTDSSGAPLLQVYC
The following text describes a protein:
Function:
Reduces the stability of FtsZ polymers in the presence of ATP.
Subcellular Localization:
Cytoplasm.
Sequence:
MSEMTPSQRYAAGVQRGDWRADPAQQAALAELDRIHEALVDSAQDGWLDRLSAFWKKPEPVRGLYFWGGVGRGKTFLVDLFYDGLPIKQKYRTHFHRFMRGVHERLREHAGQSDPLAKIAQEWRENLRVLVLDEFFVTDIGDAMLLARLLERLFAEGVTLVTTSNTAPENLYANGLQRDSFLPAIGLLQKFCVELYAEGTEDYRMRALTRSPVYRAPLDAQADGWLAQRWAELSGNAEARSGNIEIEARKIAVRARGKSIAWFDFAALCEGPRGPADYIEIAREFTTVLLGGIPHFDRMNEDAARRFVNLIDELYDRHVNLVCTAQDAPPALYSGQRLAGAFERTASRLIEMQSADYLATAHRA
The following text describes a protein:
Function:
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
Subcellular Localization:
Cytoplasm.
Sequence:
MPAFHVAWRAARSLASRRHDANSLITIGRRRSHLQLCSHTSAAAPGSATAAPATDASEAASNAAWGEQAFSALQKKATSRLHRFYVPQPLGPTPEPATLEALLGVAPSTTSTSAASTSTRSGSSGSSSSGGGSGSQAAGPAADAAPGKRRKAGSSTAAAAAASATADAATAAWAGSVAAGVPATLVLEGEEARHAARALRLAAGDRVELCDGRGNVAVGVVTGTDKQRVWVSTEGAASHQRWSGPRWVLAVACTTLKGGRAEWLVEKATELGAFMLVPLVTERSQAGGKAKFRTSRSGGGGGGGGSDLDWGSDGGGGDDYQPGRLERVAIAATKQSLRPHALALVPPTPLADLLPLVRRAAAGEGGEAAAASRAAGGAGGGGEGSVVGGVTQPGFSLVAVAGAPPLMSVLQQLRSGSGVGASTDPGGCADSNPVAEAPPSASSPAGQGGAAAAASAAAAAAAAAAAVASNSPVRVLFVGPEGDFTPAELAALVEAGAQPVGLGVNRLRTETAAIGLLSACLFSD
The following text describes a protein:
Function:
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MEAKLLQSLHLTTWTGSDSVFPKPNNSMGLSTRFERKRRVNMLKCNLVQTVKPVTGRRASGLKVSCASQNSPASVLESETFTTEEDLVLKKSEEIEPCLSGRCIYLVGMMGSGKTTIGQILAEVLGYSFFDSDKLIELSVGGTTVADIFKLHGEAFFRDNETEVLHKLSTMHRLVISTGGGAVVRPINWKYMHKGISVFIDVPLDALAQRLTAVGTASRPLLHHESGDAYTQTLKKLSKLWEVRSEAYSNAQVRVSLERIAAKLGHGDVCCVNPTQIAIEALIQIEDYLKK
The following text describes a protein:
Function:
Required for the final endonucleolytic cleavage at site D converting 20S pre-rRNA into the mature 18S rRNA. Required for the final steps of cytoplasmic maturation of the 40S ribosomal subunit. The association with the very late 40S subunit intermediate seems to follow RIO2 association with precursors of the 40S subunit and may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. The catalytic activity regulates its dynamic association with the 40S subunit. Has a role in the cell cycle where it is required for entrance into S-phase and in the control of the onset of anaphase. Appears to also be involved in the maintenance of chromosome stability and correct mitotic segregation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSLEDKFDSLSVSQGASDHINNQLLEKYSHKIKTDELSFSRAKTSKDKANRATVENVLDPRTMRFLKSMVTRGVIADLNGCLSTGKEANVYHAFAGTGKAPVIDEETGQYEVLETDGSRAEYAIKIYKTSILVFKDRERYVDGEFRFRNSRSQHNPRKMIKIWAEKEFRNLKRIYQSGVIPAPKPIEVKNNVLVMEFLSRGNGFASPKLKDYPYKNRDEIFHYYHTMVAYMRLLYQVCRLVHADLSEYNTIVHDDKLYMIDVSQSVEPEHPMSLDFLRMDIKNVNLYFEKMGISIFPERVIFQFVISETLEKFKGDYNNISALVAYIASNLPIKSTEQDEAEDEIFRSLHLVRSLGGLEERDFDRYTDGKFDLLKSLIAHDNERNFAASEQFEFDNADHECSSGTEEFSDDEEDGSSGSEEDDEEEGEYYDDDEPKVLKGKKHEDKDLKKLRKQEAKDAKREKRKTKVKKHIKKKLVKKTKSKK
The following text describes a protein:
Function:
Has a dual activity phosphatase/phosphodiesterase in vitro, with a preference to phosphoenolpyruvate (PEP) and 2',3'-cAMP, respectively. Can also use 2',3'-cGMP, 2',3'-cCMP and various model substrates such as p-nitrophenyl phosphate (pNPP), bis-p-nitrophenyl phosphate (bis-pNPP) and p-nitrophenyl thymidine monophosphate (pNP-TMP).
Sequence:
MRVLFIGDVFGQPGRRVLQNHLPTIRPQFDFVIVNMENSAGGFGMHRDAARGALEAGAGCLTLGNHAWHHKDIYPMLSEDTYPIVRPLNYADPGTPGVGWRTFDVNGEKLTVVNLLGRVFMEAVDNPFRTMDALLERDDLGTVFVDFHAEATSEKEAMGWHLAGRVAAVIGTHTHVPTADTRILKGGTAYQTDAGFTGPHDSIIGSAIEGPLQRFLTERPHRYGVAEGRAELNGVALHFEGGKATAAERYRFIED
The following text describes a protein:
Function:
Converts proline to delta-1-pyrroline-5-carboxylate.
Sequence:
MVCVSSLLRLPRLVRNRRVFYRFSSTLTSNQEKEISFADHRTAYAHLSRAEILRAWIVLKLCSFDFLLQNSLKVLETSQRVFGQGLLEKILRPTLYDQFVAGDDPQSLKETASKLKQLGIKLMILPSLEEDIGQKSDQNRYNDNVEVTLKLAEIAYQHGGPLSCLQTKITALISADLLVKQENIELEMGLERLKSVGAFASGLQLRLLVDGEFTYLNRAISIAALSMAGAFNQTRPVVWNTYQCYLKDAFDKICGEFDVARRMGVGFGAKIVRGAYLERERLLSAEGNYPDPTNPSYEATSAVYDRVVQHMVEQVAALGGQRCNVIVASHNETSVLKALSKMGSLGILPTDNTVVFGQIYGMASNITVKLASEGYVVYNSVPYGSLFDVLPYLSRRATENRAVLKGTRRERTLLARELRARFLGF
The following text describes a protein:
Function:
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Sequence:
MSRRDGPAGANLNAEREKIRREIEELERSLQLDVTSVDVAVSDSSLSSDDAEGDSSDAHAEMEVEREEDSSDDDLESSLLEDPETCLQMNYVYQEVIQEKIEEVELLIAQNKEQQKEILCELDGRKTTRTGDGRNLPSNIFLGHFMKPYFKDKTTGIGPPSNEDAKEKAAQGIKSFEQLLSTKWKSKEKVLLQKSVVSDRLQRLLQPKLLKLSYSNQKLENVKTEMEKQILEKQIKEVEREIEAINQLPESDLLGGRFDEHDWEKIANVHFDGRRSSEELKKFWQNWEHPNINKNEWTEEETERLKDIAAKRGYLDWQTVAQELGTNRTAFQCLQKYQAYNKDLKRKEWTRDEDKMLLELVQEMRVGSHIPYKKIAYYMEGRDSAQLIYRWTKSVDPSLKKGPWTPEEDAMLLAAVEKYGERDWYKIRAEVPGRSDAQCSDRYLKALHRDVKKGKWSLKEEEQLIDLVQKHGLGHWSKIASELPHRTRSQCLSKWKIMIGSKKRSRSAKRQHAEESSSCSESSSEDVELDLSDTSEEEKMNKEECTFPSIDLWIPTQTDVLESCQGRHQASSPFSFGSANARTSSSKIPNARREGGEEGANAKATELSTILRGMARPHSTDITVKNPKEEINKASRCGKQVLRVTLEDVRRVLRENTCFQRKRQSKLIMSSAATLTKTSGVGASAAEKHRGLWSTMGKSRRQERARWRKMNLDRKLLMAVTPWVGDVLLPCTLRAGKMAFDQTKAYSIQQKLKSVSLSSTPLFTLFIQLFRIDTNGCMKIIRERRADAARPQQASQNLESSSGNASQPPSNTQRALPALPSPPAPLAQAHRQKPKTVSELLREKRQMEKQLKEKAMQTKVFVAPQMMLSGPLIIQHPPQQMIPSAQVGSKPGAGGSTDSQVQCVSASPSAFTSVAGSASTPVVLESHSPSVPKVGELPGSSQETKVQSNKELNEQGPQNTPERGLFPSLNPAAAGKAPDRGGCNAQVLAGTSAPVVFQNQAFVPRRVTVVPFGIDSGNSKLSLPAPITYELTHSGPVNLLPALLAPQPGSHLTPDSMLPLTWVVTQQALLSSAVQAVVGVPQGLQAIVRSQSQASVTSSGSVSGLGAPPVSSGVNMPHPSHAETKTNPQLAAGSPAGKTAGVSHSASVFPVSSADPVCSVSGVSSATSAHSDSSSKTVDSSAAHNALPGGAPTLHAQLLPQMQLPASTEGSDSRCVTDVVSLGEKQDSSTTNGSSSNSDVLHKGDELQPRASIPHNSVAGNSEGSADQGLKYRPIASKPPPEQTESAPPQPTTSSAEKTLLDYSLISLEDDELVKEWLSGKQGVQVPPLQTRLPYFPPFLCNLKTLSKLLLQKAALEKQAARFLSPDGSQTEGEVDLNAITKLVHEKLGDDPAFLLLKARFLAAFTLPAVLATLPPPKVATTLSASKREYGESDEEEWQSEEEASEDESCGDELDAPSDETGGDEPGDRDADFPSKGMETEDSAAQSIVGTCTDGTASVPQIRRSVRIRKRFTKRRRV
The following text describes a protein:
Function:
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
Sequence:
MLRAPFRVLGVSHCKESLEITWQDGAVSQFPSAWLRNSVRDDIIFDTQTFIYNQRSFADFSAKESPIISASYKQESDDVSVEWPDHSTVFNASWLRARDSTNANHLTNGKDLELWDASNKLDITYDFAERKGKLSSWMNDLRKYGIAFFKDVPANDTGLRDLLESIGQVMQRTHPTNHLTISVDPQKIAESDLHIYSPDKHPVHMDTSYYSAPARLTGLLATEYNAPVEDTVNYYVDSLKEVCM
The following text describes a protein:
Function:
Involved in mitotic spindle assembly checkpoint signaling, a process that delays anaphase until chromosomes are bioriented on the spindle, and in the repair of incorrect mitotic kinetochore-spindle microtubule attachments. Acts as a kinetochore scaffold for the recruitment of other spindle assembly checkpoint components.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Chromosome, centromere. Note=Recruited to kinetochores and centromeres during the early stages of mitosis when cells start to form a spindle and kinetochores are unattached, when spc7 is phosphorylated by mph1.
Sequence:
MSDWRLTENVLDQNIPETKPRESKTRLEEIQRLALFQEELDIIEELDDPVDVWYRCIEWLLETRFLGMETVNKMLDDAIQYLERCRFALNDVRHLLIQLAKIKQSYETPDELQQAAKQFYQLASKGIGLELALFYEEYGSLLIRMQRWKEASEVFHAAVSREARPLVRLLRNAAEFSRAYDLHNAHPSIHDAPYSSPFPPPRIVLGSKPVSSSTLPSKPKSFQVFSDASSSRDSQNASDLPQAKSLESEANTPNLPLLYDKSSGKRVEYSAFNFLALYENGEERSMEECRAQRYLSSIQPNTAASFPKVVPKNEISVHHDSSSSNVSPIYKNPVAEQSDTPTRSLPKNYAYVAKSTSPELKVFDTVMPVALSPKPAQKPPSPTIHTKAALADILDIFNQPLRSESLEKSSKSPISAQSSYLGTPLKNDENSSNSGATSLTGRSQEEHLDFIPSLTPSKNYPSKIYSPNKNLDFSHTASKAETYKNSNELENVKREQPFSELLPSTLQEETATGTTSTTFANAKRRPEDSNISPTNPKKLHTLPRSPQYSTVDSNSVLSPAMPKGYMFVNENQSMKHESSVSNPVATIPHENGKHDFGQLSPIEHKPFFPKNDDELPGPSGYLTMPYEEAMASLSNLPTLINPLDQSLRDLLFQVLRPSLLRDKDYHEHETSFALVEHIESFVSKIKPKAGGPGRRRSSNRHSLDGPEFHLFYPPNTNLSVISKLGQGAFAPVYLVKSKIETENGDVSQGGAENNESKLFALKIETPPSCFEFYLTRQAMTRLKGLRETNSILPVHQLHMFHDTSHLLMDYRPQGSILDLVNSMHNSTFSSSGMDEILVVFFSIEFLRIIEALHTHKIIHGDLKADNALLRLETVADSEWSPIYSPEGLYGWSFKGIYLIDFGRGIDLSLFEEKVKFIADWDTDLQDCIEMREGRPWTYQIDYHGLAAIIYTMLFGQYIETRIEVINGQRRQVLTQRMKRYWNQDLWHRLFDLLLNPTLHVSEENLPMTEELSKIRIEMEEWLVNHSTGGSGLKGLLKSIEKRKI