lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
Sequence:
MNNFGNEEFDCHFLDEGFTAKDILDQKIHEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAAIGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTSRLLLERAKELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFPPEVEEQDASTLPVSCAWESGMKRHRAACASASINV
The following text describes a protein:
Function:
May function as a transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MAELFMECEEEELEPWQRRIPEVVDDDDDDDDEPIFVGEITSSKASANSRQRPVSRSAGASATSQPAQRPSPAPSSAQPVCRGIPAPIVPQIVTQHVSRTVTAVTAQPIIINNQGYIMSSPQISGSSTLMLGIKASSGGTQYPSGTSIAVLPGRPVQQITQVHQVTPVRTVSNFSHRPQVQVSSTIQSSILSLAHVQSSSQPSSAKLQPVQMTTTKLQPIQLACNSTNPAAKRSSASDGNGNVPKKAKLDAGTPPSASGNVKNGAPFLKACPKCNIHFNLPEPLRNHMRRTCIMAQSMSADAEKGKLIMLVNEFYYGKHEGDFGLGQQEQKTNTTFKCCSCLKILKNNIRFMNHMKHHLELEKQSNESWENHTTCQHCYRQYSTPFQLQCHIESAHSPYESTTNCKICELAFESEQVLLQHMKDNHKPGEMPYVCQVCNYRSSFFSEVENHFRSVHENTKYLLCPFCLKVIRSGTPYMQHYMRHQKKGIHRCTKCRLQFLTCKEKMDHKTQHHRTFRKPRSLEGLPPGTKVTIRASLASGGSPASPNSSSKSIISIIPNSPNAKQSHKSQSSQARSRSSSQNKKQERLNNSKLSGRCTLALRNLRNHLGVQKCVECYTEIKDFPSHYPTFVNCHMCTYRTSCTKAFANHMMRFHTASSRDRLQKRTRPPGSLRGLTLVCLNCDFLTDSSGADSMSKHLTDRQNHTCQVIVEQ
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAGPELLLDSNIRLWVVLPIVIITFFVGMIRHYVSILLQSDKKLTQEQVSDSQVLIRSRVLRENGKYIPKQSFLTRKYYFNNPEDGFFKKTKRKVVPPSPVTDPTMLTDMMKGNVTNVLPMILIGGWINMTFSGFVTTKVPFPLTLRFKPMLQQGIELLTLDASWVSSASWYFLNVFGLRSIYSLILGQDNAADQSRMMQEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEEELMAKDLHFEGMFKKELQTSIF
The following text describes a protein:
Function:
Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside). The reaction proceeds in two steps with the monoglucoside as an intermediate.
Sequence:
MSHFAIVAPPLYSHAVALHALALEMAQRGHRVTFLTGNVASLAEQETERVAFYPLPASVQQAQRNVQQQSNGNLLRLIAAMSSLTDVLCQQLPAILQRLAVDALIVDEMEPAGSLVAEALGLPFISIACALPVNREPGLPLPVMPFHYAEDKRALRRFQVSERIYDALMYPHGQTILRHAQRFGLPERRRLDECLSPLAQISQSVPALDFPRRALPNCFHYVGALRYQPPPQVERSPRSTPRIFASLGTLQGHRLRLFQKIARACASVGAEVTIAHCDGLTPAQADSLYACGATEVVSFVDQPRYVAEANLVITHGGLNTVLDALAAATPVLAVPLSFDQPAVAARLVYNGLGRRVSRFARQQTLADEIAQLLGDETLHQRLATARQQLNDAGGTPRAATLIEQAIAGSESVS
The following text describes a protein:
Function:
May be a global positive regulator of transcription. Binds a cis-acting element of its own promoter DNA sequence and is hence probably also involved in its own transcription activation. The recognition sequence is 5'-WHGAWNH-N(3-5)-WHGAWNH-3', where W is A/T, H is C/A/T, N is G/C/A/T and the linker length in the middle is 3 to 5 nucleotides.
Sequence:
MAGPKHVLLVSEHWDLFFQTKELLNPEEYRCTIGQQYKQELSADLVVCEYSLLPREIRSPKSLEGSFVLVLLDFFDEETSVDLLDRGFWYLIRPITPRILKSAISLFLSQHSLHSVPESIRFGPNVFYVLKLTVETPEGSVHLTPSESGILKRLLINKGQLCLRKHLLEEIKNHAKAIVARNVDVHIASLRKKLGAYGSRIVTLRGVGYLFSDDGDKKFSQQDTKLS
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
Sequence:
MASGWGMTGNKGRCYDFWMDFSECMSRCREPKDCSLLREDCLECLHHSKEVKSP
The following text describes a protein:
Function:
Regulate neuronals morphology via inhibition of the WAVE regulatory complex (WCR), a complex that controls F-actin cytoskeletal dynamics.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MCPSEMGTLWHHWSPVLISLAALFSKVTEGRGILESIQRFSLLPTYLPVTYHINNADVSFFLKEANQDIMRNSSLQSRVESFLIYKSRRLPVLNASYGPFSIEQVVPQDLMLPSNPFGFTNKFSLNWKLKAHILRDKVYLSRPKVQVLFHIMGRDWDDRSAGEKLPCLRVFAFRETREVRGSCRLQGDLGLCVAELELLSSWFSPPTVVAGRRKSVDQPEGTPVELYYTVHPGGERGDCVREDARRSNGIRTGHSDIDESGPPLQRIGSIFLYQTHRKPSLRELRLDNSVAIHYIPKTVRKGDVLTFPVSISRNSTEDRFTLRAKVKKGVNIIGVRASSPSIWDVKERTDYTGKYAPAVIVCQKKAAGSENSADGASYEVMQIDVEVEEPGDLPATQLVTWQVEYPGEITSDLGVSKIYVSPKDLIGVVPLAMEAEILNTAILTGKTVAVPVKVVSVEDDGTVTELLESVECRSSDEDVIKVSDRCDYVFVNGKEMKGKVNVVVNFTYQHLSSPLEMTVWVPRLPLQIEVSDTELNQIKGWRVPIVSSRRPAGDSEEEEDDERRGRGCTLQYQHAMVRVLTQFVAEAAGPGGHLAHLLGSDWQVDITELINDFMQVEEPRIAKLQGGQILMGQELGMTTIQILSPLSDTILAEKTITVLDEKVTITDLGVQLVTGLSLSLQLSPGSNRAIFATAVAQELLQRPKQEAAISCWVQFSDGSVTPLDIYDGKDFSLMATSLDEKVVSIHQDPKFKWPIIAAETEGQGTLVKVEMVISESCQKSKRKSVLAVGTANIKVKFGQNDANPNTSDSRHTGAGVHMENNVSDRRPKKPSQEWGSQEGQYYGSSSMGLMEGRGTTTDRSILQKKKGQESLLDDNSHLQTIPSDLTSFPAQVDLPRSNGEMDGNDLMQASKGLSDLEIGMYALLGVFCLAILVFLINCVTFALKYRHKQVPFEEQEGMSHSHDWVGLSNRTELLENHINFASSQDEQITAIDRGMDFEESKYLLSTNSQKSINGQLFKPLGPIIIDGKDQKSEPPTSPTSKRKRVKFTTFTAVSSDDEYPTRNSIVMSSEDDIKWVCQDLDPGDCKELHNYMERLHENV
The following text describes a protein:
Function:
Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Nucleus outer membrane; Single-pass type I membrane protein.
Sequence:
MQETLLRVFVVVVGLLVCPKDDPRLQQWDEVLTTGLQKPEERQWREEEQTVAPVSEKTLAESDKKTQDYTNRNVEDQSLSGTVAREKVSMPELNAAVTQQLLEEEIPRLQGEPALEASQSADEQKRKYLLIYRTSDEPESLQEPESLQGEPTKPEMTHSQASPVHTKMADKKSSGRASAQFETEYLKHIWNAFSIISTICFFWKYLGGNIRKNHEEPKAFSGTSMAAEAPLPDASVLHQFYVKCVQAPPEKTCREEEFMEGFANDLLTAMRSVCDEDGRMRVEDFHIVSVKEIIIPLAPPEPYGFRCLLSNDEGGVPPTEMQVCGQIKLVEEAVVLNGCPCQAPGADGDVVCLVHCEPKPIRKKVSDARDGPLCSKNTHFLSKSRVTRWFQSTLKQAWALISHKYDFDLILCYIEAPGALTIRFRSGKKLSFRMNPVVRFNAEAHFFIAPWSSSDLDTFWPLSLSGYEEQLMHKLSEQLPENSCHIQTLEITLFLHRRHATWFGSTALRDFHFKAALMHLLLKKKPSDWGRGEAGCRLRDLLTFVEKSLQKKLLKHVLLGNSSITLMKLPAEITKAKPVNLLQPLAEHDCVYRTPCSEGREPGASCQRPASGAAGAEG
The following text describes a protein:
Function:
Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. Plays a role in caveolae kiss-and-run dynamics (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Note=Upon EGF stimulation, translocates into the nucleus.
Sequence:
MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKPSSPKKQNDVRVKFEHRGEKRILQVTRPVKLEDLRSKSKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHMKSLKILLVVNGSTQATNLEPSPSPEDLNNTPLGAERKKRLSVVGPPNRDRSSPPPGYIPDILHQIARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFTDYDNPIFEKFGKGGTYPRRYHVSYHHQEYNDGRKTFPRARRTQGTSFRSPVSFSPTDHSLSTSSGSSVFTPEYDDSRIRRRGSDIDNPTLTVTDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPSAEELLRHMFVHYH
The following text describes a protein:
Function:
May play a role in abiotic stress response.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MGDEAEIKEHLKPQASSETIDKKHNVKGKRLWQKVKYQLVEFHSLPAYLRDNEYIIGHYRSEWPIKQILLSIFTIHNETLNVWTHLIGFFLFLALTIYTATKVPSVVDLHSLQHRLPDLLRKTDLHKLHSELMSRLPSSPSSWHVMDLLYNCLPERFSHGNYTDMCVLHSVREDLANLIAPLIFRPITRWPFYAFLGGAIFCLLASSTCHLLSCHSERVSYIMLRLDYAGIAALIATSFYPPVYYSFMCDPFFCNLYLGFITILGIATVLVSLLPVFQSLEFRVVRASLFFGMGFSGLAPILHKLIIFWDQPEALHMTGYEILMGLLYGLGAVVYATRIPERWMPGKFDIAGHSHQLFHVLVVAGALTHYRAGL
The following text describes a protein:
Function:
May play a role in endocytic and/or exocytic pathways.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MESTFHSDTLDSFPNYQENSLNTNEEQTNPLESLRDGWASSNSSSSSSLLLPDENEGNEVFGSLKGLVTQSKFGQWANKLSKSLQARRRKSESISKPRVYYSVFMAPSWVLHAEKHWEEYPHYAGYDYKDYVRLLDATKEAIAHGVFPVLISKGSSGSYFVKNKVQKNIAVFKPKDEEPYGKLNPKWTKWFHRNLFPCFFGRSCLIPNTSYLSEAAACVLDRGLGLYLVPYTSVASISSPTFNYDYFARKAFLTRNKPLPEKTGSFQQFLDGFVVASKFFAQHPWPGTRHRETREYTESVASSEDFDIFDPFLAENEIETEFWTEELRLKFRFEFEKLVLLDYLMRNTDRNLDNWMIKICYEPCDNEEYYKSINLLSTNLTPNMSANSVDPAISQTSDFWKGPHFQIGAIDNSLAFPYKHPDSWRSFPYGWLSLPRSLFTQPFTEFTRQLFLHKLTSREWWEKLSDDLRNVFNQDLDFDEKMFSRQLSLVKGQAYNIVEVLKNPLMNIYDLLELPNLYVVEDVVRIEVNEPTSANSEEAEFGLPIKRDYGSILHPSCSQTFPPYPGSQLLQATPGRSFSSNAEALLPLNYITLLSKDSSSPKMLKDVIFERLQCASSNAVFSTC
The following text describes a protein:
Function:
Stabilizes the proteasome holoenzyme, probably by tethering the 20S proteolytic core particle and the 19S regulatory particle. The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Miscellaneous:
MISCELLANEOUS: Present with 2950 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSISSDEAKEKQLVEKAELRLAIADSPQKFETNLQTFLPPLLLKLASPHASVRTAVFSALKNLISRINTLPQVQLPVRALIVQAKEPNLAAQQDSTNVRLYSLLLASKGIDRLSLQDRQQLLPLVVSNISCLTGTVAARMFHILLKLILEWVAPQESSHEQEEFVQFLQLDNDGFSFLMRQFTRFFLLVPSKQVQVSQQPLSRGYTCPGLSLTDVAFFTYDAGVTFNKEQLNKFKKAIFQFVCRGMAATQTIEQSPRMIELMEFLCVVSTDSTNLSDDAAQFMKRFPMPYENEEFITFLQTLYIGNTANGRPPVKAILQEKILSILNRSHFATTKAECISLICSIGLHSSEYKLRSLTLSFIRHVAKLNYKNLNPASSSPSSTDFSTCIVSLIRNNLHAEGWPKLQLGPQTPAFNTAILQRQLQYETLGDILKRDFELVSDLSYIEFLFESLKNDLPQFRSSIQESLLSLVGHLSILPQQSKLKLKNLLRKNLSIDEQQREDNNDAVNSIMALKFVSIKFTNAAFPFHDPEARLFNIWGTVRTNRFDIIEESFKGLQPFWFRVNNASINTSATVKTSDLLGSHLSETEFPPFREFLQVLIDQLDSEAASITRKSLNNAVRFSKQCLISNAIYGKKTMVIQDEDWSVRIDKALELDDTVVSRVNEMVQGMNDDIFIRYLTLLSNEFTATNSKGEQIAIFPYQDPIFGSVLLTLLNFVSNNVLRRLEILVPDLYHLVIMKFQSLSDNDLAVCATIIGIISTAIADSTHVKRITKIAQSQTMAETYVASYVVPRLYLKDQTNHIESDSILNLLNILTTHLSHPGTNKDMILKLVCQVTKFGLLLQVSAQERKDFLKKVMDTIQDKLINDVTAIQTWSYLSLYSTDLENSSLFQEKLLETNVSKQNDFLFSVGESLSVVAGKWSSKYLIKQIDIPNFNVEIMQQKFPATNVTTILDEIFSGCDSTKPSLRKASCIWLLSYIQYLGHLPEVSSKCNDIHLRFMRFLADRDEFIQDSAARGLSLVYEIGGSDLKESMVKGLLKSFTESTAGSASTSATGISGSVSEETELFEPGVLNTGDGSISTYKDILNLASEVGDPALVYKFMSLAKSSALWSSRKGIAFGLGAIMSKSSLEELLLKDQQTAKKLIPKLYRYRFDPFQAVSRSMTDIWNTLIPESSLTISLYFNDILDELLCGMANKEWRVREASTSALLQLIQSQPQEKFSEKMLKIWTMAFRTMDDIKDSVREVGTKFTTVLAKILARSIDVEKGVNPTKSKEILDNILPFLWGPHGLNSDAEEVRNFALTTLIDLVKHSPGAIKPFTPKLIYDFITLFSSIEPQVINYLALNAANYNIDANVIDTQRKNGVTNSPLFQTIEKLINNSDDCMMEEIINVVIKASRKSVGLPSKVASSLVIIILVKRYSIEMKPYSGKLLKVCLTMFEDRNESVNIAFAISMGYLFKVSALDKCIKYSEKLITKYFEPTSTENNKKVVGTAIDSILNYAKSEFDNVASVFMPLIFIACNDEDKDLETLYNKIWTEASSSGAGTVKLYLPEILNVLCVNIKSNDFSIRKTCAKSVIQLCGGINDSIPYPQIVKLFDISREALSGRSWDGKEHIVAALVSLTEKFSQTVADNNDLQESINHVMYTEVSRKSMKYVKKILPLYARYINVNPQEETITFLIEKAKEMIRLLGSESDDSEGSIKQTSDESTIKRIKPNTEITQKSSKENIENEEYVINLLKVSVDICNNSKSRYPMNLLEFIIDEIAYLFHNDRIIHTWRTQLAASEIGISIVGRFSTISSADFIQNVGRLWDQTFPINCNKETIENVKLQMIKFGGLIIQKIPSLQNNIEENLRLLNSIDSTSRIELELKNIGL
The following text describes a protein:
Function:
Putative pheromone receptor.
Miscellaneous:
MISCELLANEOUS: The variant protein sequence (Ref.3) is capable of binding the sex pheromone, 2-octanamine (2-1, methyl heptyl) via aa 11-17.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MASRQISLALGFLAFLWAVLGAQNKTEEVQCRLMAKFNLSGYVDAKNHSLVIAGLFPIHSRIIPVDEAILEPVSPMCEGFNFRGFRWMKTMIHTIKEINERKDILPNHTLGYQIFDSCYTISKAMESSLVFLTGQEEFKPNFRNSTGSTLAALVGSGGSSLSVAASRILGLYYMPQVGYTSSCSILSDKFQFPSYLRVLPSDNLQSEAIVNLIKHFGWVWVGAIAADDDYGKYGVKTFKEKMESANLCVAFSETIPKVYSNEKMQKAVKAVKTSTAKVIVLYTSDIDLSLFVLEMIHHNITDRTWIATEAWITSALIAKPEYFPYFGGTIGFATPRSVIPGLKEFLYDVHPNKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDQLCTGEEKLEDLKNTYLDTSQLRITKQCKQAVYAIAHGLDHLSRCQEGQGPFGSNQQCAYIPTFDFWQLMYYMKEIKFKSHEDKWVILDDNGDLKNGHYDVLNWHLDDEGEISFVTVGRFNFRSTNFELVIPTNSTIFWNTESSRRPDSFCTQVCPPGTRKGIRQGQPICCFDCIPCADGYVSEKSGQRECDPCGEDDWSNAGKSKCVPKLVEFLAYGEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQMSLVITVLSSLLFIGKPCNWSCMARQITLALGFCLCLSSILGKTISLFFAYRISVSKTRLISMHPIFRKLIVLVCVVGEIGVCAAYLVLEPPRMFKNIEIQNVKIIFECNEGSVEFLCSIFGFDVLRALLCFLTTFVARQLPDNYYEGKCITFGMLVFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTTVSTVLDE
The following text describes a protein:
Function:
The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MILAVLFANSKGNILVERPDSLDFFTKLPSLFAWSGLFTLFTWCLEMSASMLLCKYEYDELALAEVIFVITSAVKDVCGKLPTERLFLGKYGRICLTLDEIIWKIFFSSELELMELLDGHCDILALIAYQFEDINVLYCYFHDLTNLRLYITQIIWYCVFPVTHMYITCYVVSTGIIGIMRPLHLHELLMKLYQLRF
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as a non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells; Glutamate-gated receptor that probably acts as non-selective cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Nucleus.
Sequence:
MNINGIKKQNEIILMDKHGVKCVTKLVKDGSKYGKRGLGKGCKDFCEANDVLKIGQPFMSELVWEDSVPVLTILRKQVHSIRFDTLNNNIIYDFSNHLCNKRALPYRPPRCFLSLQVLTMTREHYLALNLLFLVIVLLMQVGEGQQNRASDVKVGIVDDVGMAYSNMTLFCINTSLSDFYSSHPETWTRLVTTVVDSKKDVVIAAASALDLITNNEVKAILGPWNSMQAQFMIEIGQKSQVPIVSYSATSPFLASIRSQYFFRATYDDSSQVHAVKAIIKLFGWREVVPVYVDNTFGEGIMPHLTDALQEINVRIPYRTVISPNATGDEISVELLRMMTRPTRVFVVHTEDLLASRFFAKAKEIGLMKQGYVWILTNGITDGLSLMKEAETDAMQGVLGVKTYVPRSDKLEAFKSKWKNRFPLSDLSVYGLWAYDATTALAMAIEEAGASNLIFAKTDDAMRNMSGLQGLGVSQYGPKLLQTLSKVRFKGLSGDFRFINRELQPSVLEIVNVNGHGGRTIGYWTKEHGLLKYVDQRQATTTTFTTWKDRLRPIIWPGDTTFVPKGWEIPTNGKRLKIGVPTNNHFPQFVKGTKDPITNSTIFSGFCIDYFEAVIQAMPYDVSYDFFPVEDMDYETMVHQVYLGKYDAVVGDTTISANRSMYVEFSLPYTPLLSFFIIAVVVWVLEHRVNPDFDGPGRYHYTLVLFLHHGERVLSFWARLVVIIWYFLVLLLTQSYTASLASLLTSQQLYPTVTNINSLLAKGERVGNQRSPFILGRLRESGFSDANLVTYGSPEQCHELLDTEPAKGGVSAVFMELPYVRLFLGQHCNKYKMVQTPFKVDGFGLVFPIGSLLVADVSRAILKVEESNKANQLESAWFKKIDESCPDPLTSPDPNPSESFRKLGIDSFWVLFVAAAIVCVTALGKCMFHFLKENPDQRNLQGLWESPPERHAVIDLVAASHRRQDPCKHRVCFMLELGLHSRSAMY
The following text describes a protein:
Function:
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
Subcellular Localization:
Cytoplasm.
Sequence:
MNTTANPSNIIVGLSGGVDSSVTAALLKQQGYQVRGVFMQNWEDDDNDEYCSIKQDSFDAIAVADIIGIDIDIVNFAAQYKDKVFAYFLQEYSAGRTPNPDVLCNAEIKFKCFLDYAVGQGADTIATGHYARKEVRNGVHYLLKGLDRNKDQSYFLYRLKPFQLERAIFPLGGLEKPEVRRLAAEFKLPTAAKKDSTGICFIGERPFREFLQKYLPTDNGKMVTPEGKTVGEHVGLMFYTLGQRKGLGIGGAGEPWFVAAKDLTKNELIVVQGHDHPLLYTRSLVMNDLSFTLPERPKAGRYTCKTRYRMADAPCELRYLDDETAELVFDEPQWAVTPGQSAVLYDGDICLGGGIIQTTDKPVIITR
The following text describes a protein:
Function:
Probable palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Domain:
The DHHC domain is required for palmitoyltransferase activity.
Sequence:
MTSFMSRVWCKVESTGRQLPIVLNAVLVFSITAEVSYLVLVEAPFEPEQKKTDWSTIWTGLHLFAQYFMLGNITWNASLFVKTNPSIRGVFLGGDTLGQGWRYCYNCETHTPPRCSHCYDCNVCVLRRDHHCVFFGQCVGFHNYRYFLTCLLFMWAGLLYAVVMNAEVFIFILKEGVTFHSVMLLLVPWIMLVSGQVTTRAFAFAFIADTCVVGFLLVAAFLFFHVALMLRGQTTREWYSTRRPYSLGTMANIRECLGKNWYFCWLCPLIPSPLPGDGINFKVTASLEPKKQAVH
The following text describes a protein:
Function:
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
Miscellaneous:
MISCELLANEOUS: Present with 195 molecules/cell in log phase SD medium.
Subcellular Localization:
Endosome.
Sequence:
MAGDSISADGTGVHPVELSVYSVLSTDLDGLYQSINELRESQALLILMLRKVRDKLRREGQVLYDPEPFKPTMDKLADLSARVRILSQRYEELQGNARALNN
The following text describes a protein:
Function:
DNA repair protein required for FANCD2 ubiquitination.
Subcellular Localization:
Nucleus.
Sequence:
MSKQSSCAIMGKSLSFSLSRGERADLEMPTDPLVLGVKRMMFDRETSTFLLISTVFLNINEKDSHLKILCCNCVSDLRTRINLPCVLIQCRKYNSEAFKYCILLLHNLNRVERLLSFELNHALDENTKIFDGPIVFWQYLNQFFYISSAIGKVTTISLMLSSIEWIGEIENFGLGFLGLAEPSEDKCTQKLSESDYEFSNSSLCAYALKSQEMLSNGYLIPLAYSTMVTHVHVWAAEMVDHQLRTSLIALTRKNQLILFQNGIPVRACQLPFPGPRSVQILDAGKRNRFFIVSFPSKACAVSEKKFKVVAKWEQLSLVLVNDFAGVGTEQVLVVFEDSLDADQLTSFTVTDFVKIWYSTKPLDCCEDPLAEEEHENYYLVLPALEGQLDNSFIFLNKIQQHISFKDKFIAKSWKALLNAVYGKGDSLPSDEMVKLDQDGLVPFCDEGEDSVPTPEENLPDNFPEPEHIVEQTWCHVLDDDLVVGAKVTSLKESNEMTLSLIMNQGNRSSFHLMKCHSQVWLLKHMKCERIQECTEIYLYKKLRNCGALFSWEQRTASEGILTIYCRSQGVLFQCLDHLIKVLPEICSFKYLKVENEDFLVDHLSSTLEAELVTFCSVSTSAFEYVRGGYNCRIRRTDNRAMTFLGRRAKIRQSKRKVQRERILKHLNMTVNGSSYAEMTLALAEIQLKSDLIVKTLANFVIAL
The following text describes a protein:
Function:
Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses. Upon activation by various ligands such as PGLYRP1, HMGB1 or HSP70, multimerizes and forms a complex with transmembrane adapter TYROBP/DAP12. In turn, initiates a SYK-mediated cascade of tyrosine phosphorylation, activating multiple downstream mediators such as BTK, MAPK1, MAPK3 or phospholipase C-gamma. This cascade promotes the neutrophil- and macrophage-mediated release of pro-inflammatory cytokines and/or chemokines, as well as their migration and thereby amplifies inflammatory responses that are triggered by bacterial and fungal infections. By also promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptor (TLR) and NOD-like receptor engagement, plays a major role in the pathophysiology of acute and chronic inflammatory diseases of different etiologies including septic shock and atherosclerosis.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MRKAGLWGLLLVFFVSEVKAAIVPEEERYDLVEGQTLTVNCPFNIMKYARSRKAWQRLSAGKEPLTLVVTERSSTTSSEVRVGKYTLKDDPTEAMLFVQMTDLQVTDSGLYRCVIYHPPNDPVLLFHPVRLVVTKGSSGVSVPDIIPTTKPTEVPVLITTKHSTPTRSLPKSTAVVSSPDPGVTINNGTDPTSVSTYNVVVPVVCGLLIKTLIFFVLFVVTKRSFG
The following text describes a protein:
Function:
Catalytic component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Decapping is the major pathway of mRNA degradation in yeast. It occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body.
Subcellular Localization:
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Sequence:
MSFTNATFSQVLDDLSARFILNLPAEEQSSVERLCFQIEQAHWFYEDFIRAQNDQLPSLGLRVFSAKLFAHCPLLWKWSKVHEEAFDDFLRYKTRIPVRGAIMLDMSMQQCVLVKGWKASSGWGFPKGKIDKDESDVDCAIREVYEETGFDCSSRINPNEFIDMTIRGQNVRLYIIPGISLDTRFESRTRKEISKIEWHNLMDLPTFKKNKPQTMKNKFYMVIPFLAPLKKWIKKRNIANNTTKEKNISVDVDADASSQLLSLLKSSTAPSDLATPQPSTFPQPPVESHSSFDIKQKILHLLNEGNEPKSPIQLPPVSNLPLNPPIQSSNSRLSHDNNSFDPFAYLGLDPKNPSASFPRVVSQNNMLTNKPVLNNHFQQSMYSNLLKDQNSVQHLFAASDMPSPMELPSPSTVYHQVFYPPTSTSVSSYGLGKTPQPAYGSSSPYVNGHQTQQISSLPPFQSQTQFLARNSDNSGQSYNSEGDSNSKRLLSMLSQQDTTPSSSTLSKEANVQLANLFLTPNSLETKKFSDNSQGEEISDNLHGESCNNPNANSVHSAQLLQALLHPSATETKEETPKKTSDSLSLLTLLKSGLPTPANDLQNKSQNNERKASSQVKELEVKNYSKSTDLLKKTLRIPRNDEPLEAANQFDLLKVSPQQKSEVPPKRNELSQSKLKNRKKKENSETNKNHVDMSPGFVKILKRSPLADQKKEDTQESDFKGSDDHFLSYLQSVVSSNSNGLH
The following text describes a protein:
Function:
Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes.
Subcellular Localization:
Nucleus.
Sequence:
MSRRKQAKPRSLKDPNCKLEDKTEDGEALDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHGGEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPAGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTVHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHSS
The following text describes a protein:
Function:
RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA).
Sequence:
MSEIDTNDIKKEMDNKNYRDPTDNKELLKWTKKKRKRSNDSMHINNFYRYNPPNFKLLASKYPTFDKYIINKTEKIYNIDWKDSNATKELTRVLLDHDFGLRIELPDNYLCPTLTLRINYLYWISDQLKNLKIILNDNDNDNKIIKGIDIGTGTSCIFPLLGAKLFNNWSFIGIDIDDKVLEYAQNNITINSLNSKITLFKNEKNSDILLKLLNYKEGSNTFNSSNDDHQDNHDDDDDDEEYFADFCLCNPPFFKDLNENNNNKNNNPKSNCTGSVNEMVTDGGEFEFVKRIIKESFQLKCKIRFYTTMIGRKVNLNPLINILIKQYYLPKNQIQTTELVQGNTSRWVLSWYFLNKSTNLETKENNNINNNNNNNNNNNINNNNQFLTRMERRKLYREGITLNLDSDDNNNNNNNNNNNNNNNNNNNNNNNNNNNKIVEIIKLILDNNDIIYKTDENNIKYECKYLLNNVIVGSSIKLDRDIEFLFTIFIDLTTRLILFKPIDPKINNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNSCDGEIINSNLFFILKFLENIKNEIKLK