lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 34 of the tRNA anticodon loop of substrate tRNAs. Required for the correct positioning of the substrate tRNA for methylation. Required to suppress amino acid starvation-induced autophagy. Enhances the STK11/LKB1-induced cell growth suppression activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MRSTVLLAPVTALEFLGEEYLLSGEGPVLSVYSLHTSSTAPRQPGATLSVLRNHRIHGIRPAPRRQESGEGGSQQQPRPHEEREGGALLAVFGGKAVCVVELREEERAGGSPRLAELCPLWELQDWVWDAHWLQGRRHLAVALAHNAVVLCDPWARVALALSRCAEGCLLYSALLLGPSWAGLVVVGGTVFSQLVLWGPAQGESAGGGGGGPAVQRRLEGHEGVVFGIAYLPESGWLASASDDRSACLWQVGSLGGPAGCGSESPVRLWALYGHQARVFAVRLLRGRLLSAGEDSLCLLWDGHRGSVARRFKGHRAGGVRALAVSEGGGGGHWAATGGADGGIRVWRIGGDGEGEGGPGRGCASAPRRSLCDLRFRGRGSPKVVRLAGFGAQGHLRVVVLTDEGCVYLHSSGEGGGEGWQPLGGEGDPEFRSYSVLELAEAGGGAALCAVGNLAGGVRVFALEQPGGALELRAGRGKVHSLHWASERGRGGEEEPGRWQLFASGPEGQVYRWEVCAAGGRGGQQALGVRPLRPLLLPACAKRWLTAVAALPGRGALWAAGDRRGSVLLYRGAREGRGGPDEPPLGPVSVLFGLHGKQGVTSLRAQGGLLYSTGRDGCVRVLGVRSGDEAEERPDTLEVLRAQRTCRGMDWVERVLFPETGRFLVLGFHSVDFVVWDPVRRERLLSVPCGGGHRSWSYCAPSRANAGPGWTPSLGDGFAFIKQGGVFLSRGRGPPLSGFGVPLELKEGVHGRGVACVCRVGAVRSEAGAWWEVLVTGGEDTTLTVLGVQPDCGSVRVLSIIADHISSVRALATVPQPEGETGAQEPSCLSALLFSGGGRAQLQSYRLLIGWNRQEGTPSCQVIQVAGHRLAEQWEKRRNRHKMLKMDPETRMIEWSVCWLRVTDALLLPRLFSLHESLRRLVLLWGSLHHQRCVLSVAPFSLCSPQGTRSQFLCSAATDGRIALWDLTEVVEGAEGLTAAPQCWGEGSPCLCVPAHQSGVNSLAVWGSASSECLLLASGGDDGSLTVSRIGVQYNTRDTGGASASLRLLGQTSAPCAHAAPLTALQFLTSDLLATVSVDQRVALWRLCGEGRLRWQGALFSHVADAAGLVVW
The following text describes a protein:
Function:
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).
Sequence:
MSGGSRGIVALFKSTDETISNDDRYLSILEENNFIGMLVPTLSFQFQTEHLRECLNQPEKYSGMILTSQRSAESVNKAVADLSDAWKEKRHYCVGIKTAETAATLLGLKNLAGQDCGNAENLSSLIVQEFQNGYLPLPLLFPCSSLKMDTLPRTLAQHDVSIEIVNSYVTVPHPLLQDFVLQLSHKVKYKTI
The following text describes a protein:
Function:
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MTVKIRLRAPQGVSTLDLDPETTTVEDLKVLIFSSTEIPPDEQDIKYGYPPKPLPSTAGPLSSIPIGKGEQLIVSSIPSGGPSKKVPVVAQPSTTTSSAPAASRPTNASPVLAAPLVSNASQGEGVESGESVAVPGRDAGYLQLRVVPDDNSCLFSAIGIVFEGGIEAAQRLRMVVANAIKDDPFTYSEVMLGQPIDQYVKRIQKPQTWGGAIELSIFAKHYKTEIASFDVATGRCDRFGQDEYDTRCILVYSGIHYDAISLSPLPVSPASFHTTIFPVTDQIILTTADKLVSQLRARHYYTDTANFDLRCAICKKGLRGEKGAREHAMQTGHVEFGEY
The following text describes a protein:
Function:
Lipolytic acyl hydrolase (LAH).
Domain:
The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
Sequence:
MSASARSLAAGARLLLPQTSIVRNAPSQFEHSASPLLLPSRAGFFRPDARTSARPSWLTGPASLWSSASSPNGSMDGEPTRSGTEDEPRGGGGGGSSGDEGSTEDKKRRAQARLEQVKRGLEAGTLGFGFSAGGFLYPYHLGVLWELHELDILKDYKVQMAGASAGSLAVATYNCGLEPEKATQALHEFAENCRANGTRYRLGGLLKDFLHAYLPDDAHERCRGNTHVALTRLFPVVRSELISEFESKDDFVNALLTSCHIPFYFNGSWMTEFRGRFYMDGGVAAFIPRPPTPHAVKVCCFPVNEVLATVQDRVAQYERVAALLDVAISPDASEPWPFSYPQMVSWALVPADDDMLRYMINKGRRDARAWAQRMELVPQDAAAGRTEGEGAGDVGGGAERGAARVAEAEERREAEGAAGGVEDTGARQGGEGGATARSEAEAEAVKQAAGGGKK
The following text describes a protein:
Function:
Transcription activator that binds to as1-like elements (5'-TGACGTAAgggaTGACGCA-3') in promoters of target genes. Regulates transcription in response to plant signaling molecules salicylic acid (SA), methyl jasmonate (MJ) and auxin (2,4D) only in leaves. Prevents lateral branching and may repress defense signaling.
Subcellular Localization:
Nucleus.
Sequence:
MGFERAFVESSPEQENKLFVGVSYMDSSNKNQDPSESNNQISFGGQHQHHQQQFFYNHHQQQQLQNNNQVSFGMMQQSSSAIPGSLISKDSAGAYDLGELDQALFQYLDGQEPSSIQEQRQNSGMRPPTLNIFPSQPMHVEPSTTNKMNTGLVSPAISGSKRSSQPSMELSNNLKNNDAPSASGPEPPKAAKREGNRKGPTSSSEQDAPKTPDPKTLRRLAQNREAARKSRLRKKAYVQQLESSRIRLTQLEQELQRARAQGYYFGGNSLLGGEQNLPVNLANMSSDAAVFDMEYARWLEEHHRLMCELRNAVQEHFPENELRIYVDNCVTHYDEIMNLKSMLTKSDVFHLVSGMWKTPAERCFMWMGGFRPSELLKIILSQIEPLTEQQLMGICGLQQSTQEAEDALSQGLEALNHSLSDTIASDALSCPQNMANYMGQMALAMNKLSTLEGFVRQADNLRHQTIHRLHQLLTTRQAARCFLAIAEYFHRLRALSSLWHARPRQE
The following text describes a protein:
Function:
Plays a specific role in mating-type regulation of yeast, by acting post-translationally to control the stability or activity of the SIR4 proteins.
Miscellaneous:
MISCELLANEOUS: Present with 172 molecules/cell in log phase SD medium.
Sequence:
MSESGQEQNRGTNTSPNNAENNNNSNAASGPLNGGAEQTRNITVSIQYSYFTPERLAHLSNISNNDNNENNSAASGSTIANGTGPSFGIGNGGHQPDGALVLSFRDVPASTPQDRLNSFISVAAQLAMERFNRLLNRPKGISKDEFDKLPVLQVSDLPKAEGPLCSICYDEYEDEVDSTKAKRKRDSENEEESEGTKKRKDNEGAPLRTTADNDSNPSITNATVVEPPSIPLTEQQRTLNDEETNPSYKHSPIKLPCGHIFGRECIYKWSRLENSCPLCRQKISESVGVQRAAQQDTDEVAANEAAFERIRRVLYDPTAVNSTNENSSAPSENTSNTTVPTIGNASSGEQMLSRTGFFLVPQNGQPLHNPVRLPPNDSDRNGVNGPSSTTQNPPSNSGGSNNNQSPRWVPIPLTLFQFHSPNPNPSASDSSASPSAANGPNSNNTSSDATDPHHNRLRAVLDHIFNVAQRGTSDTSATTAPGAQTVHNQGRNDSSSSDTTQGSSFLENISRLTGHFTNGSRDNNNDNNHSNDQQRGGSTGENNRNNLFSSGVASYRNQNGDVTTVELRNNNSAAFPPTDENPSQGQGSSSSDTTIHNDVPNDNNEQRSSQ
The following text describes a protein:
Function:
Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
Subcellular Localization:
Cytoplasm.
Sequence:
MLNTEDILCKMLFAQLQSIGFFTESKSQPVLENFYGRWFEESQSILERHQFLKRTENGHVPTRSIGTMSELWKEWNEQKFDLLQDNNMKAMVTLVETALKALPEILTGKASATDILFPNSSMDLVEGVYKNNQVADYFNDVLADTLTAYLQERLKQEPEAKIRILEIGAGTGGTSAAVFQKLKAWQTHIKEYCYTDLSKAFLMHAENKYGPDNPYLTYKRFNVEEPASEQHIDAGGYDAVIAANVLHATKNIRQTLRNAKAVLKKNGLLLLNEISNHNIYSHLTFGLLEGWWLYEDPDLRIPGCPGLYPDTWKMVLESEGFRYVSFMAEQSHQLGQQIIAAESNGVVRQKKRTEAEEDPSHIQMNAEIDHSQESDSLIEQTAQFVKHTLAKSIKLSPERIHEDTTFEKYGIDSILQVNFIRELEKVTGELPKTILFEHNNTKELVEYLVKGHENKLRTALLKEKTKPAKNEAPLQTERTDPNKPFTFHTRRFVTEQEVTETQLANTEPLKIEKTSNLQGTHFNDSSTEDIAIIGVSGRYPMSNSLEELWGHLIAGDNCITEAPESRWRTSLLKTLSKDPKKPANKKRYGGFLQDIEAFDHQLFEVEQNRVMEMTPELRLCLETVWETFEDGGYTRTRLDKLRDDDGVGVFIGNMYNQYFWNIPSLEQAVLSSNGGDWHIANRVSHFFNLTGPSIAVSSACSSSLNAIHLACESLKLKNCSMAIAGGVNLTLDLSKYDSLERANLLGSGNQSKSFGTGNGLIPGEGVGAVLLKPLSKAMEDQDHIYAVIKSSFANHSGGRQMYTAPDPKQQAKLIVKSIQQSGIDPETIGYIESAANGSALGDPIEVIALTNAFQQYTNKKQFCAIGSVKSNLGHLEAASGISQLTKVLLQMKKGTLVPTINAMPVNPNIKLEHTAFYLQEQTEPWHRLNDPETGKQLPRRSMINSFGAGGAYANLIIEEYMETAPEKEHIAPRQQEFTAVFSAKTKWSLLSYLENMQLFLEKEASLDIEPVVQALHRRNHNLEHRTAFTVASTQELIEKLKVFRTSRESSLQQGIYTSFDLQPCAESASRDREINAAEQWAQGALIAFKEADIGNRTGWVHLPHYAFDHNTSFHFDVSSINEKSSDVEDNINQPVIQDQFTYDEPYVQGHVFNNERVLVGATYGSLAIEAFFNLFPEENSGRISKLSYISPIVIKQGETIELQAKPLQKDQVIELQIMYREPSSGLWKPAAIGQCGIGSFEPKKVNIENVKHSLTKLHHIDQMYKTGNGPEWGELFKTITHLYRDHKSILAKIRLPQSGLANGHHYTVSPLMTNSAYLAILSFLEQFDMTGGFLPFGINDIQFTKQTIKGDCWLLITLVKNTGDMLLFDVDVINESSETVLHYSGYSLKQLRISNQRGNQNKAIKASNLKARIRSYVTDKLAVNMADPSKLSIAKAHIMDFGIDSSQLVALTREMEAETKIELNPTLFFEYPTIQELIDFFADKHEASFAQLFGEAHQQEERPAQIENQMKQIPAYETNTDKTIEHAADGIAIIGMSGQFPKANSVTEFWDNLVQGKNCVSEVPKERWDWRKYAAADKEGQSSLQWGGFIEGIGEFDPLFFGISPKEAANMDPQEFLLLIHAWKAMEDAGLTGQVLSSRPTGVFVAAGNTDTAVVPSLIPNRISYALDVKGPSEYYEAACSSALVALHRAIQSIRNGECEQAIVGAVNLLLSPKGFIGFDSMGYLSEKGQAKSFQADANGFVRSEGAGVLIIKPLQKAIEDSDHIYSVIKGSGVSHGGRGMSLHAPNPAGMKDAMLKAYQGAQIDPKTVTYIEAHGIASPLADAIEIEALKSGCSQLELELPQEVREEAPCYISSLKPSIGHGELVSGMAALMKVSMAMKHQTIPGISGFSSLNDQVSLKGTRFRVTAENQQWRDLSDDAGKKIPRRASINSYSFGGVNAHVILEEYIPLPKPPVSMSENGAHIVVLSAKNQDRLKAIAQQQLDYVNKQQELSLQDYAYTLQTGREEMEDRLALVVRSKEELVIGLQACLAEKGDKLKSSVPVFSGNAENGSSDLEALLDGPLREMVIETLLSENNLEKIAFCWTKGVQIPWEKLYQGKGARRIPLPTYPFEKRSCWNGFQAVENTPSVSQDERINNSSDHHILANVLGMAPDELQFHKPLQQYGFDSISCIQLLQQLQSKVDPLIVLTELQACHTVQDMMDLIAKKQEDTSLQNDQARTFPELIPLNDGKRGRPVFWFHGGVGGVEIYQQFAQKSQRPFYGIQARGFMTDSAPLHGIEQMASYYIEIIRSIQPEGPYDVGGYSLGGMIAYEVTRQLQSQGLAVKSMVMIDSPYRSETKENEASMKTSMLQTINTMLASIAKREKFTDVLISREEVDISLEDEEFLSELIDLAKERGLNKPDKQIRAQAQQMMKTQRAYDLESYTVKPLPDPETVKCYYFRNKSRSFFGDLDTYFTLSNEKEPFDQAAYWEEWERQIPHFHLVDVDSSNHFMILTEPKASTALLEFCEKLYSNRGVVNANFLKAFRKKHEAREEKETDELVKR
The following text describes a protein:
Function:
Involved in protein precursor import into chloroplasts.
Subcellular Localization:
Plastid, chloroplast inner membrane; Multi-pass membrane protein. Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MLLFNPVTSLSVPLTLSPKTHYSPSLSSLKNHPSFLTNKNHNPTRRKLLIVQAKGEDSADGPDRLISAICYFYPFFDGIQYGKYVITQFTPIQVLIQPLFPAIKVFKSFPLNGFLVFLTLYFVVVRNPNFGRYVRFNTMQAIVLDVLLIFPDLLERSFNPKEVAKVAYCR
The following text describes a protein:
Function:
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
Subcellular Localization:
Nucleus.
Sequence:
MDFFRMGDSEVAPFIAFLASMNREERGRLISDPSFCLFLFRLFSPSTQSLILSLIWDSTQLIRIDERIEPDISCVTLLEQLDIVLQNGVNNTKILNPIFRRGYLSGALEGSHRSSRFVPINSEKDIDKKKKKDKDVVKKSNERWECLLRFLALPSESTVQNVSSTTRDVLNHAGFTSGHGTDIEITSKGFQFLLLSPVKQIWSYMIELLKMETREGRSVKELLDVLLRMALCIHSEPENKKYEVDNSWTERQCNFVTHLRELGLIFIRKRKDGFFYLTPNLANLCLANHDDSLTKKSGSIIVETNFRVYAYTSSSLQLAILSSFTCMTYRFHDMSVGILTRDSVRKALQVGITANQIISFLKTNCHPESLSTSLPIPITVSDQIRLWEDERKRLIYQEAALYSSFESEKVSWIKYICII
The following text describes a protein:
Function:
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
Subcellular Localization:
Nucleus.
Sequence:
MAKKKTLKQQDFQKKKLKVGKPKQAASNATDTSFVAKTIHLPNQTKLTSTNDAEADLLRRLSLCKHHSEITRKETLIYLQVAVPRVIHGQVASRLMSACIPLMCDPNKHVREELLKLLDVVGSCDANTMRLYMRPLVLFMGSAMTHISAGVQRDSGRFLQCVLRHAGHELVRAAWVKMLRGLCNVLGWPLRGAASASAGAGSNVVSMHKNRALQHQNLQALADFIRLGCAEPAAAALAGCAAPALYAKYLLPDCPQPYSHLKLFVREFPADTAAAARPLHELDTLVCEDAATRRDVFLGHFRPVLAAQLPSLVKDGGDCGRVAANLLQLLDHVQQAAA
The following text describes a protein:
Function:
Component of the MIS complex, a complex that mediates N6-methyladenosine (m6A) methylation of meiotic mRNAs and is required for initiation of meiosis, progression through the meiotic divisions and sporulation. May assist STE12 in the pheromone-dependent expression of KAR3 and CIK1.
Miscellaneous:
MISCELLANEOUS: Present with 1690 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MAFQDPTYDQNKSRHINNSHLQGPNQETIEMKSKHVSFKPSRDFHTNDYSNNYIHGKSLPQQHVTNIENRVDGYPKLQKLFQAKAKQINQFATTPFGCKIGIDSIVPTLNHWIQNENLTFDVVMIGCLTENQFIYPILTQLPLDRLISKPGFLFIWANSQKINELTKLLNNEIWAKKFRRSEELVFVPIDKKSPFYPGLDQDDETLMEKMQWHCWMCITGTVRRSTDGHLIHCNVDTDLSIETKDTTNGAVPSHLYRIAENFSTATRRLHIIPARTGYETPVKVRPGWVIVSPDVMLDNFSPKRYKEEIANLGSNIPLKNEIELLRPRSPVQKAQ
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MGYRLLRDNVFKASCAKDSDELRARREPTMLYKEDQLVAPASGTERRYTLVLDLDETVIYAREGPLYARAYLKELLSFIRKNFEVIVWTAGEREYAECILEEINIRNTVRHLIHRHKTWFSFDDYTKDLTKLGRNLDYVIIIENSPDCVRTNPQNGIIVDDFRVSQTPPMEEAEAAWEGDGNNRERKAGSRSDSKTRRQVTDRTLLLLREVLKAMVESGETVPDFLAKCPLLTQRRVIGSDGSQIQTYHLGTRRKRGIPQLCASSPKRRRVTKESAPGATCTS
The following text describes a protein:
Function:
Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MEEIPPTHYAASRAASVAENCINYQQGTPNKVFKVQTVQQASKEDIPGRGHKYHLKFSVEEIIQKQVTVSCTAEVLYPRMGQGSAPEVNFTFEGEIGKNPDEEDNTFYQRLMSMKEPLQAQNIPDNFGNVSPQMKPVHHLAWVACGYVMWQNSTEDTWYKMAKIQTVKQVQRNDDFIELDYTVLLHDVASQEIIPWQMQVLWHPQYGTKVKHNSRLPKEAPAE
The following text describes a protein:
Function:
Loads pcna onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSRSAEEVEATLQIAKVDLEDLRNTVHCLTFSSDFTSGDYSLMELDDTLCKQIEAGDSLVIRGDKSDHAVLCSQDKTYDLKIADTSNLLLFIPGCKTPDQLPADQQPLTIINCEIAGFSNHYWELRRCRPKLKKLKKLLMENTYNGPENERESQDNSLHTTEDLLNMIQASNEELVDHLKAIHACSINGFWRLLDFDYEMKLLNHITQLIDSESWSFSKVPLPVCLQELRSLEPEEMIEHCLTCYGKRLIDEGTGGDFFALDEDKICRATALMLLQNAVKFNLAEFQEVWQQSVPEGMNTRLDQLKGLALVDRTSRPETIFLLKTEDLPEDTQERFNTLFGMREKWAEADIAPYIKDLCGEKQTIGALLTKYARSSMQNGIKLYNSRRPLS
The following text describes a protein:
Function:
Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
Subcellular Localization:
Cell junction, adherens junction. Cell junction, focal adhesion. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell projection, podosome. Cytoplasm, cytoskeleton.
Sequence:
FHRVENACTKLVRAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKMNQAKGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERREILGTCKTLGQMTDQLADLRARGQGATPMAMQKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLADPNGGSEGEEHIRGIMAEARKVAELCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARALAKQIATSLQNLQSKTNRAVANTRPVKAAVHLEGKIEQAQRWIDNPTVADRGVGQAAIRGLVAEGRRLANVMMGPYRQDLLAKCDRVDQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKTRMQEAMTQEVSDVFSDTTTPIKLLAVAATAPSDAPNRDEASIPRAANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEAINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ
The following text describes a protein:
Function:
Binds polysaccharides in a Ca(2+)-independent manner (By similarity).
Subcellular Localization:
Secreted. Endoplasmic reticulum. Golgi apparatus. Endosome.
Sequence:
MLHPETSPGRGHLLAVLLALLGTTWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGIPTPSLASGLWRTLQVGWNMQLLPAGLASFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQTAIEAFVCAYSPGGNWEVNGKTIIPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFHTCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGLVWLSAAMGFGNCVELQASAAFNWNDQRCKTRNRYICQFAQEHISRWGPGS
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.
Subcellular Localization:
Cytoplasm.
Sequence:
MSELCSSKLGTKEHWDSVYNTEVENFVDHGEEGEIWFGEDSVDKMVTWASIVSCMAFIKVLDETMRITIQVIDLGCGNGHLLFRLEDLGFVNLTGVDYSKESINLSQKIGSSHTPPSKASFACLDILNLDDISGAVHASTMDHRIRYTLALDKGTLDAISLCEKTGEKSPADTYVETVAAMIKPGGVLLLTSCNWTEAEILDRFKAGTIHVKDGSSHSLFEFMDRIKYPVFKFGGAVGQTITSVALRRL
The following text describes a protein:
Function:
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MGRVEYSPLFETRRCRGRFIYRSFAISLFVAICFIWHYRFSHITKGEDGNWAWLGMLASELWFGFYWVLTQALRWNLVFRQPFKNRLSQRYEKKLPRVDIFVCTADPDIEPAMMVINTVLSVMAYDYPTEKLSVYLSDDAGSQITFYALLEASNFAKHWVPFCKRFKVEPRSPSAYFKSLVSSGYPTDPSQAKELGNIKKLYDEMEKRIEDATKFGEVAKEARLKHMGFSQWDSYSSRRDHDTILQILLHKNDHNNSKDVDGFVLPALVYLAREKRPQYFHNFKAGAMNSLLRVSSNISNGKIILNVDCDMYSNNSQSVRDALCFFMDEEKGQEIAYVQFPQTFENATKNDLYGGSLTSILEVEFPGLDGYGGPLYAGTGCFHKRESLCGMKFSDQYCNDWNSEDDQFKEANLQELEQQSKVLASCNYEENTLWGKEMGLKYGCPVEDVITGLSIQCQGWKSVYYNPPRKAFLGLAPTTLPQTLVQHKRWSEGDLQILLSKYSPAWYGFGRINFGLQMGYSVYCLWAPNCLATLYYSIIPSLYLLKGIPLFPKISSPWFIPFAYVIVGETTYSLLEFFFCGGTFQGWWNDQRIWLYKRTSSYLFACIDTILKLFGFSESTFTITTKVTEEDASKRHEKEIMEFGTSSPMLTVLATLALLNLFCFLSVLKDAILGEGDIGAYETMGLQVLLCGFLVFINLPIYQGLFLRKDNGRLPSSIAIKSIVFALGVFISFIFT
The following text describes a protein:
Function:
May be involved in DNA replication and thus regulate cell proliferation.
Sequence:
MHRRSPNIARRSLMRDLIVLQKSRSLRDPSASPPSWASPYNVGGFARKSERKATTNGRWISIGDNCRREAGRLSVSLPLVRSVATAKVTAAEATGDYVFEEIDRDAEITKVEEAGIRSHKSDSLSGNQVSSKDTHKKVVGQRKREPNKSADGQAVCPKTLSEQLEEVPGQTDDFNKKKSGLFQHGRHESKRRTNNAVEENTCDHYRRSNRGKKCRLKGARRACRSIDLRGIGDYRNLTNASDSVAVASKNQKAHLENVEEDTELKAAWTQRNVCGIPWNWSRIHQQGKTFLDIAGRSLSCGLSDFRTKKAEGLVPQREGNTSNMATALDHLTPTSSDSEVLPLLTEVLEFQGNGANCLPSKGYSGELEIFSNHSLRHYTDSDLSSDARSSQKRYRLFAHGRHRSLTQKYMPKTFKDLVGQNLVVQALSNAIMRRKVGLIYVFHGPHGTGKTSCARVFARALNCLSEEDFKPCGVCSSCISNDLGRSRDVLELGPVGNFDFESIKDAFDNMMLLPRSSMYRVFILDDCDGLPSNLWSTISKVIDRSPRHVIFVLICSNLDSLPHIIISRCQKFFFPKVRDSDIISTLQWIATSEGLEIDKDALKLIASRSDGSLRDAEMTLDQISLLGKKISLPLVQELVGLVSDEKLVDLLDLSLSADTVNTVKSLREIMETGVDPLALMTQLATIITDILAGSYVFTQDRLCRKFFRRQTLSKEDMERLRKALRTLSETEKQLRASSDKLTWLTAALLQLAPDQQYMLPSSSTDRSLDHSPMLLNNSHVIDIHGGSTNKLDDMQLLDRSFSRGVGQGYNNNISGNELSHSVTMANGRGPAKPSEAIEASDLHNTGKRYDNIEKIWQAVLKHIPSDTLRWFLYNEGSLKSVSLGAAPTVQMAFSSNANKYRAEKFRGQLLQAFESVLASPVMLEISCRSRNTVRLDAPAAPLLPSSESGSSKMTVKQQYVKNKNSLNSVSENLAGKLIEENILGRICSGQARWLHPGPPVMTEDEIVEAGPHELRLTNKTVGSMEKGFENVWEEASASCHHSNLVSLSERKDNEQNQRKNLVSGQVSLAHVIQQAEGGWSRCKAMSVAEKLEQENFRLEPRSRSLFCWKVHRTTRAKCLNMKIRRKPQSLSKLIICGRCLHTASPK
The following text describes a protein:
Function:
Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MASRCSEPYPEVSRIPTVRGCNGSLSGALSCCEDSARGSGPPKAPTVAEGPSSCLRRNVISERERRKRMSLSCERLRALLPQFDGRREDMASVLEMSVQFLRLASALGPSQEQHAILASSKEMWHSLQEDVLQLTLSSQIQAGVPDPGTGASSGTRTPDVKAFLESPWSLDPASASPEPVPHILASSRQWDPASCTSLGTDKCEALLGLCQVRGGLPPFSEPSSLVPWPPGRSLPKAVRPPLSWPPFSQQQTLPVMSGEALGWLGQAGPLAMGAAPLGEPAKEDPMLAQEAGSALGSDVDDGTSFLLTAGPSSWPGEWGPGFRAGPPA
The following text describes a protein:
Function:
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin. Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription. Global regulatory protein that plays positive as well as negative regulatory roles in transcription.
Miscellaneous:
MISCELLANEOUS: Present with 1240 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Domain:
The acidic C-terminal domain mediates interaction with histone H3/H4 complexes.
Sequence:
MSFLSKLSQIRKSTTASKAQVQDPLPKKNDEEYSLLPKNYIRDEDPAVKRLKELRRQELLKNGALAKKSGVKRKRGTSSGSEKKKIERNDDDEGGLGIRFKRSIGASHAPLKPVVRKKPEPIKKMSFEELMKQAENNEKQPPKVKSSEPVTKERPHFNKPGFKSSKRPQKKASPGATLRGVSSGGNSIKSSDSPKPVKLNLPTNGFAQPNRRLKEKLESRKQKSRYQDDYDEEDNDMDDFIEDDEDEGYHSKSKHSNGPGYDRDEIWAMFNRGKKRSEYDYDELEDDDMEANEMEILEEEEMARKMARLEDKREEAWLKKHEEEKRRRKKGIR
The following text describes a protein:
Function:
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA); Catalyzes the final step in the metabolic pathway of hydroxyproline.
Sequence:
MHNIFKGLITALITPFKDNKLDLYALERILKYQIKHEVDAVLIAGSTGEGSSLSFEEYKLLLQTSVEIVNKRIPIISGCSSNNTAYARELAAESTKIGVDGFMASPPSYVKPTQHGIYKHFEALHEACNLPIMLYSAPTRSGVDFSDETILKLSKLLRILALKDCGVDLERPLRIRAIVKEDFNILTGNDEVVLAFNAQGGVGWTSVASNIAPNICKELLEKWYKNDTKGALGIHQKLLPLYKALFVESNPIPIKYAAHYLGLCENEIRLPLTEASDSAKKQIENIITSLSIKI
The following text describes a protein:
Function:
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MINRFLIALSFLTVLPLKFKEINEKELIRSIIFFPFIGFLEGVFCIFLVNIFKQIFSSSVISIILLVFLFSVRGIFHIDGLSDTFDALFYKGTGQKEKDLQQRLQIMKDSVIGVAGAVALVLDVLCRFAFVKELIDINQFLIFLFMFCFSRWIVIPLMYYGKPARTTGLGVLFIGKISSWQVIISTVLPIFLLVYFTIEKNFIFLPLIALFLFFISYILKKFFERKFNGITGDHLGATVEITEIVFLICFLLGEKLWLSY
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MKSFTLLICYGLFVLHAARGDEWNYPTPGTNGVMSEPERWGGQCDNGRRQSPIDLTIAAAVRGQFAPLFFSNYMLPLKQPRVTNTGHSIQINNRDSAITMQGGGLGGRFVLDQMHFHWGSEHTLDDTRYGLELHLVHHDTRYASLEDAVQARNGVAVLGVLFHVGSQPNMHIDTILDTATEIQNEVGKEALLRGKLSPYNLLPSNRTSFYRYEGSLTTPACAESVIWTVFTESISVSLEQVERFKAIHDQTGRELVNNFRSVQPLNTRALVYATEWDQQGNNFATKMTSNVVFLGAIVLLVITSRLSYH
The following text describes a protein:
Function:
Transcription factor that acts as a key regulator of ciliogenesis. Specifically regulates expression of genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Required for neural tube closure and neural ciliogenesis.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Mainly expressed in the nucleus and at lower level in cytoplasm.
Sequence:
MQNSDSGSDSATSVALRTSTSAQAPVVQPVPASQQVQTVQHVYPAQVQYVEGDTVYTNGAIRTAYSYNAETQIYAPSSGSSYFDSQGGGAQVTTVVSSPTAIPSHSMVGITMDVSGSQIISSSGAYLIHGGLENSRHTPSHTSRTFPATLEMAIENLQKNEGITSHKSSLLNSHLQWLLDNYETAEGVSLPRSSLYNHYLRHCQDHKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRIQEDAQYMAIRQQPIHQKQRYRPAQKIDGMGENPANSSQHASPEQSVAAQSQHHQQFIDTSHVFPDFPAPDLGSLLLPEGITMTDIKNLQLMYRRHCEATIDVVMNLQFQYIEKLWQAFWNSKPSSPDGSNPMSSEDEQEPIIPNEKLMVLCKYEPIMRWMRNCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMCDFPQQIVHAKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCDEGMVQKLEQDFKLTLQQQSSLDQWANWLDNVVTQVLKPHEGSTSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEFSDFASMSPVQMDKDDVSELGSDTEGDPHISGQPPVKRERVELNHSMQEM
The following text describes a protein:
Function:
Required for G1 arrest and mating in response to nitrogen starvation. Ago1 regulation of cytokinesis and cell cycle checkpoints occurs downstream of dcr1. Required, indirectly, for regulated hyperphosphorylation of cdc2. Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation, accurate chromosome segregation, centromere cohesion and telomere function during mitosis and meiosis. Required for silencing at the centromeres and for initiation of transcriptionally silent heterochromatin at the mating type locus. Promotes histone H3K9 methylation necessary for centromere function. Required for recruitment of swi6 and cohesin to an ectopic dg repeat. A member of the RNA-induced transcriptional silencing (RITS) complex which is involved in the biosynthesis of dsRNA from primer siRNAs provided by the RNA-directed RNA polymerase (RDRC) complex. Has ribonuclease H-like cleavage (slicing) activity towards target messages complementary to siRNA and can direct site-specific cleavage of RNA substrates via siRNA. Slicing activity is required for both post-transcriptional and transcriptional gene silencing as well as for histone H3 'Lys-10' methylation spreading, conversion of double-stranded siRNA to single-stranded siRNA and siRNA-dependent association of ago1 with chromatin. A member of the argonaute siRNA chaperone (ARC) complex which is required for histone H3K9 methylation, heterochromatin assembly and siRNA generation. The ARC complex contains mostly double-stranded siRNA.
Subcellular Localization:
Cytoplasm. Nucleus. Chromosome, centromere. Chromosome, telomere. Note=Associates with telomeric and mating-type region heterochromatin.
Sequence:
MSYKPSSEIALRPGYGGLGKQITLKANFFQIISLPNETINQYHVIVGDGSRVPRKQSQLIWNSKEVKQYFGSSWMNSVYDGRSMCWSKGDIADGTIKVNIGSESHPREIEFSIQKSSKINLHTLSQFVNSKYSSDPQVLSSIMFLDLLLKKKPSETLFGFMHSFFTGENGVSLGGGVEAWKGFYQSIRPNQGFMSVNVDISSSAFWRNDSLLQILMEYTDCSNVRDLTRFDLKRLSRKFRFLKVTCQHRNNVGTDLANRVYSIEGFSSKSASDSFFVRRLNGEEQKISVAEYFLENHNVRLQYPNLPCILVKNGAMLPIEFCFVVKGQRYTAKLNSDQTANMIRFAVQRPFERVQQIDDFVHQMDWDTDPYLTQYGMKIQKKMLEVPARVLETPSIRYGGDCIERPVSGRWNLRGKRFLDPPRAPIRSWAVMCFTSTRRLPMRGIENFLQTYVQTLTSLGINFVMKKPPVLYADIRGSVEELCITLYKKAEQVGNAPPDYLFFILDKNSPEPYGSIKRVCNTMLGVPSQCAISKHILQSKPQYCANLGMKINVKVGGINCSLIPKSNPLGNVPTLILGGDVYHPGVGATGVSIASIVASVDLNGCKYTAVSRSQPRHQEVIEGMKDIVVYLLQGFRAMTKQQPQRIIYFRDGTSEGQFLSVINDELSQIKEACHSLSPKYNPKILVCTTQKRHHARFFIKNKSDGDRNGNPLPGTIIEKHVTHPYQYDFYLISHPSLQGVSVPVHYTVLHDEIQMPPDQFQTLCYNLCYVYARATSAVSLVPPVYYAHLVSNLARYQDVTADDTFVETSEASMDQEVKPLLALSSKLKTKMWYM