lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MADSKTLDQVNTDLNNVVSRMDIVEKRLAVEAKQVDGPVGGADLREYQTHMLLKLRAIRDTMEKEGSSLEQLRKERDVARAERDDLHKQVNKLNYRVQHLKQHLMAKSGEAERVLQLHGAVCATGKASTASPSTSPSCSSLETQLTALCSAEGATHDEQQLIRAFLAASRSSQTLVARRLLANPALECFPNLLQFFLRVLMAAHAQSHDQSADNGASVASSCSYSENSTQSCVIHLQEDNSEVVRAVSVDFLLPEAFHTCLAAQYGSVKRLKCEEVWHGDHMAYRCRTCGLSDSSCMCLACFDPEEHEGHDFRVYRCSSGGCCDCGDPLAWKPQGFCKKHSANRDRSGQEQEQESRMEMHPEEQQLVHLLVRRVMEFCVDVLREVHLACLRPHASENPDPFYPRRALPRTGLLRSALPSTVKIHVDRLQQTLAWLQMLSMSCLYYRNVISGMFFEELPAEFQLDATPTQTTSASSSSTQPIEEGPVDTTPTSGGSEEDEMGERGISHGPLLILDVFLKAGVLLPVETCDVLGVLYLKLLFDQAFKQKYTCHFVEWYPYFIELYLSASDENNEDGMRNLSRFIDRLFCQLFHSNAQLRELETVFASMRPTFNPNETHGVRRRRRRRPNGLPGFASDSTPSSCVEWLMVFLLEKLNDLFRSTMRLMTILPQPLIDGTSTTGVGSINGSSTSTVGIGTVPEAPPVLRTVQAVDCGRNVFKKRIYARLCSDLRTLLVHPQIAAEVLLRSFRCIGGDDCALHESSVFTQLMKTFELLQQMDLQTRHVHRHIEYESQNWTFAFVADYELKLLLSAFLTGIPACFSREVWQSITTGDNSWNQGSTGVITGGTPLNPLEADTFRPIALARAILQPVRASLAQWATRNGRPEFVSESTGLPTDPGEVATETELITSTQLEKYYEQGTVAIGGASAKSFHFPLHHMYAALIHALCGVVRPQTLDDWCELLGMGSTDGERCRDLAFWYSALDHPLRVLLFSREIKSGLWVRNGGVMLQQLVHYHSKHWRYFGLHSDLFLCQLGASFLPHGSFTRLFFHQLPFALRDSSVFGLSSLTDVNTENSNAAVRADRSRVLRQELDVVEEALRLFLQLVLAPVKLASASSPETTAVWLLEREIMHWLTLGPFTRSEVIMRTDMKLVEQIKQLPAHEWAELEEEEILTHVLERVGAYDDPVGSSNGTRTSRSGSLPGYGLKMSGSWKLKPELWTQVSPLFECFTPSEAQQCEQNIRKNLPKSPTTDQENATTAPIVLPMLPRAQYEGVSGVDMHGVLAETMLNSSYMASVLLVIFENYKRKATAEHSNQRGQNEDQESSSSITNENLLLAALHCLYVAVELLPKQLQHQQLSPAVSLSHEGDSVRQSLDDIAECFDEENSLFDKLCVEVQLEDHETQHEESSPKRAEKETTPSSLLSLLLFFTEHRRAMEDTRPVVNLILRSVREKSSTCAAYLDDLKRKHLDAKSDTKTGSDASGPNGSNRATKVDETPKPTAKEMMRKRQQQILEKMRSQQMQFLSANGDPVDDEGNENTRDNAGGHNADMDSDSDSYDESMKSEEDVEEDHEEEEDEWGFPTGQVDVRLYLDHVSSAIAQMRDKQRKTQDRRRRRRRSTRSSSITAEHDERERSSSISYDYASLDEQSTQAEECGLCRLPCDARSRDSTFGFVGMILPTNMPQKIEKGSSSAASSDGRPVVSSRLPSLRVLKPGTTDEMRMQLADSVIWSCGHAIHHSCLKAYLMSLWKQKHGRGPLETTTGEDRLLSERDMEFVCPICRRLSNCLVPRVSLGELRERASISESLGADFGSEEEEEEKKDDGQDPLAFLQWLDTQMSFRDDSPVVKRRRSRTQSSLRLRRRLLSSASKSSLSPGSRSSGGSVASHGEHDGTEQDVSIEREIGAFCHEIVLRTVRAQLYLPTLLTSSIRDEGSLDLEMQQLSSECGAQTPAWQLLLHCLEVQLRVVAREKTLLRSDVVDSLKLRSMRQLADIAAAAVAFSTPSSLAWTVVEAPADKQFESVMTRLNGLIFGQQVLFEEDESACSTKWNIRDQLQTGDTEDATDAALVGTPILCHPKLLTCFAMRMMWRQSIATPNADVAAEQLLTEAFFSARVLFTAQILQALAYLSMQSDQEGLAGETKAEIGDFQEVESLRDASAWISLMLARSRLMGGKSVVTPDAAKPATRWNAAAMEEQVSSLCLPLAQQMLLLMDVVLPMPHQHHSDSSQGDSDAKAPQVASESCAVCDGLFPISTQTSTGMPSASSLLDKCLRRLHLPPLRLFFHRQMFPSSQRALCQLWGAQLEAKAAVSRQQARSQALVSGGSPVQVDEFPLQRQVMMLSSRAAAAASAGANYRMLIPLPRVYMDLFIRYNEKPTGVCNQCAQVPQHPGLCLFCGEVLCCFSACCEAKEGGGVGECTQHAQRCGLGLGAFLLLRACTVILFLGNERRCVWGSLYVDKNGEEDPYLRRGKTLHLDSSRRLALETLLVSHSFSQNTAILQNTSRRDGRRY
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
Sequence:
MALTDIDVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMDYFEKKEKQIEQQKKIQLSTMRNQARITVLRARDNLILELLKEAKMRLSRIVSDEEFYQDLLDKLVLQALLRLLEPVMIVRCREQDFYLVQSALLRAIPQYMMLCQKHLEVQIDQTEYLSSNAAGGVEVYSSDRKIKVSNTLESRLNLAALQNMPEIRRTLFGDNSNRKFFT
The following text describes a protein:
Function:
Binds to host erythrocytes; may act as bridge between erythrocytes and merozoites.
Sequence:
MKCNISIYFFASFFVLYFAKARNEYDIKENEKFLDVYKEKFNELDKKKYGNVQKTDKKIFTFIENKLDILNNSKFNKRWKSYGTPDNIDKNMSLINKHNNEEMFNNNYQSFLSTSSLIKQNKYVPINAVRVSRILSFLDSRINNGRNTSSNNEVLSNCREKRKGMKWDCKKKNDRSNYVCIPDRRIQLCIVNLSIIKTYTKETMKDHFIEASKKESQLLLKKNDNKYNSKFCNDLKNSFLDYGHLAMGNDMDFGGYSTKAENKIQEVFKGAHGEISEHKIKNFRKEWWNEFREKLWEAMLSEHKNNINNCKNIPQEELQITQWIKEWHGEFLLERDNRSKLPKSKCKNNTLYEACEKECIDPCMKYRDWIIRSKFEWHTLSKEYETQKVPKENAENYLIKISENKNDAKVSLLLNNCDAEYSKYCDCKHTTTLVKSVLNGNDNTIKEKREHIDLDDFSKFGCDKNSVDTNTKVWECKNPYILSTKDVCVPPRRQELCLGNIDRIYDKNLLMIKEHILAIAIYESRILKRKYKNKDDKEVCKIINKTFADIRDIIGGTDYWNDLSNRKLVGKINTNSKYVHRNKKNDKLFRDEWWKVIKKDVWNVISWVFKDKTVCKEDDIENIPQFFRWFSEWGDDYCQDKTKMIETLKVECKEKPCEDDNCKSKCNSYKEWISKKKEEYNKQAKQYQEYQKGNNYKMYSEFKSIKPEVYLKKYSEKCSNLNFEDEFKEELHSDYKNKCTMCPEVKDVPISIIRNNEQTSQEAVPEENTEIAHRTETPSISEGPKGNEQKERDDDSLSKISVSPENSRPETDAKDTSNLLKLKGDVDISMPKAVIGSSPNDNINVTEQGDNISGVNSKPLSDDVRPDKKELEDQNSDESEETVVNHISKSPSINNGDDSGSGSATVSESSSSNTGLSIDDDRNGDTFVRTQDTANTEDVIRKENADKDEDEKGADEERHSTSESLSSPEEKMLTDNEGGNSLNHEEVKEHTSNSDNVQQSGGIVNMNVEKELKDTLENPSSSLDEGKAHEELSEPNLSSDQDMSNTPGPLDNTSEETTERISNNEYKVNEREDERTLTKEYEDIVLKSHMNRESDDGELYDENSDLSTVNDESEDAEAKMKGNDTSEMSHNSSQHIESDQQKNDMKTVGDLGTTHVQNEISVPVTGEIDEKLRESKESKIHKAEEERLSHTDIHKINPEDRNSNTLHLKDIRNEENERHLTNQNINISQERDLQKHGFHTMNNLHGDGVSERSQINHSHHGNRQDRGGNSGNVLNMRSNNNNFNNIPSRYNLYDKKLDLDLYENRNDSTTKELIKKLAEINKCENEISVKYCDHMIHEEIPLKTCTKEKTRNLCCAVSDYCMSYFTYDSEEYYNCTKREFDDPSYTCFRKEAFSSMIFKFLITNKIYYYFYTYKTAKVTIKKINFSLIFFFFFSF
The following text describes a protein:
Function:
Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
Sequence:
MRIAITGANGQLGRALIATLADQHTLVPLGHDQLELTDPVTVEQIAATDADVVIHAAAYTNVDGCARDPGLAYRVNGLGTRYVALGCRRIDAALVYISTNEVFAGDARRPYFEDDPPRAINPYGQSKLAGEQAVRSLVARHFIVRVAWLFGGERNFVRTVLRLAANPPAHGLRMVADEIGSPTYTFDVAAGLARLITTDYYGTYHFVNDGICSRYEFAAEILRRVGLNIPLQPIRLCDFQRDSTPPPYTPLANLAGASLGITFRPWQDALADYLGRLPNEVLPT
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MTLEGFGFATKKTSRTEDRGAMAADPNFQQKSQPLGAEEQPESCERWMSFEDVTVNFSQEEWQHLDSAQRCLYQEVMLEIYSHLLAVGYSIPSPGVIFRMEKGKEAQTAKAEFPGQRCQEKSGNDTLPQKASGKTSVYSNVASEVTRDGSWCSLLQELWQGADITKRGQQNQILLFPPGSFLKKTLSKNSDHEYQKPRETIPLGPYLISTQEGLPQYHSLPKSLDVSLGANGHNERDQLIDIVASSQLLIPGSCNANCVVTHGGEESYRSTGNGDVLSHKQPLIYGNRFQVKADQSSQCQEVLYAISLHKPEITLTVDRPIVSYNGGKAFLYVSDSLSHPFQLKVDRVVHTGGDPYKCSSCEKSFCNAAALQQHEQIHTEEKLYVCTLCGKAFSDGSAFYEHELIHKNHTPFICDICGKAFLRKSELTSHKQCHNGEKPYKCNDCEKSFKFPSQLKVHHQIHTGEKPYECRECGKSFSKTAKLKVHQRIHTGEKPYVCSQCGKAFNQKSILDRHEKLHPGEKPYKCNDCGKSFNYPSQLKVHCHSHTGEKPYKCHECGKSFNFPCELKVHYQNHTGEKPYKCRECWKLFSKMSQLKAHYRVHTGERPYKCSHCGKAFSTKEQVQEHERIHTGEKPFVCTECGKAFSSRSSFRKHQLIHTKEKPFVSQKCETGLQEATLIPHQQLHIGEKPYKCPDCGKLFNYPSQLKSHYQIHTGEKPCKCPDCGKSFSKTSQLKAHSRIHTGERPYVCSVCGKAFKQLSTLSRHEKIHMVEKPYKCSFCGKSFCSPSELKVHLLIHTGERPYKCSSCWKAFCTKVQLQEHERIHTGERPYVCTHCGKAFRSRSVFSKHKLIHRKETPFICERCGKVFLQKSELTSHLQTHIEDKP
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Mediates ubiquitination of proteins derived from mRNAs lacking stop codons (non-stop proteins) and other translation arrest products induced by poly-lysine sequences and tandem rare codons. Ubiquitination leads to CDC48 recruitment for extraction and degradation of the incomplete translation product. May indirectly play a role in chromatin function and transcription (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm, cytosol.
Domain:
The VLRF1 domain mediates binding to the 60S ribosomal subunit.
Sequence:
MKKGGFGSGGFGAFSSSTASLSYVAPPPDLSSVPQDVIVPFKNLLKRDSTTKSKALEEILACVKKSDQPVDDSVIDVWAQLYPRVAIDNNRRVRELSHNLLLELVKSAKKRIEKTLPKLVGPWVAGTFDKDKGVARAALAVSAHILDSDQKKAKFWIAFQGKLLEYSNEAIRETADSLSDERTTSKEDMEAKYYRVLGSSMAMIQHLLPTVKDDQYPDELKRFFDADTLWTLAASDDASVRRAFYQLVASYLDNKPSLLEPKLKDVGKVLVAEGPKKEQRGSAVDLLRALISVTKRFPKVWGSKSPLDRLRPLVQKGSQGGSDEFWTELDQLLAILPTSSPDYAANAPAFLKSMRTAITSREERRQNAASAWACYLNTVDRITAGSTPSPDFLQENLYPLTREYLHPSTETSTWAYAQPPHVFKAWKIVPYTTNEQVRSSAKEEWQKLGDDFAAGLSNSLPEVSPDYEKSQLELAAQGDRWFTLVQGFLRGAPSQQSFDGDADLPSVVASTSRKLLESAQDLLARRNYKPFCAAAVLKAAFTKAPVLCAKSDLIKKVFPLDDQEAFEKIVVSRSLPFLASCLGAVTPDQPDFSEQVWVKLIDAALSHGFPSGAPIVKELVSVPLPQTVAQKSEALQNFIVEAWQDFFKEEPSSPVVEQLCRASISHSVVDDKTLQSLASSFAQDIGVAGKYDPEFKALDLLLRNKSALFADAPVDLFTRLLSLEEISDSEKATKVAAIRSLIQKQYGGNKLWLEVIRLSLAEADPSSLDINTLIRHAKEILSSGVPLTDLLPSAKAWNTELYSFLRDNPDPSLSITSSFGGAYFLATESEGSTLTTQKRDRQGRSIPARMAIYTTNLFTDVDLESVQADLLELIFLTAVLANDDLTVMKENGLWSLPASEDIRTERSDEIQSFLDLGTSLLARVAGASASWKEGDLDGTSLAEMLIQSLLQQAVDFSAKALYASKALTELFQALVSVHGYPAGAKFDEWFNKLGIMKATPQTVFAAIAFLTGFDEGLASSRAVANLYNRLVSDIVGCFPSSPKTLYNVVLLNICLSVYPPAKTPVEQRKLVFALKQFTTWVQTPDEMTFGLTAEVCKGIHRILPNVAQVYGPYWREAIDYCLLLWEKARNDTPQRWPAYVLPSIRLISSMETLEDPNDDLVEALEETAVDRSKALIRLLELPHDVVNTARQILDETLCRAVQKIPLKHLTSEKDLLTNLYGLLSSGSREVQTAAFGLLHRALPAQQEEEVLETLLEEKVAKVPDELLSIIQAVPELEKYTDEELAGFPVDVRSYLLGWHLVFDAYNQAPLQVRKQYTDSLKADNSLNALLELMFDVLGHSTGQALNLDKNTFSAEHIRSYDVSQSEEGTKERDMQWLLVHLFYLSLKFLPGLVKSWYLDLRSKQTKIALDSWMAKYYAPLLISDALDEVNDWASSQEAPQEDEKELRVRVNRTAKEVSAGYEIDEDFASIAIKIPAGYPLESVEVIGENRVAVNEKKWQSWVRATQGVITFANGSITDGLAAFRRNIIGALKGHTECPICYAVVSADKKLPDKRCSTCNNLFHRLCLYKWFQNSNKNTCPLCRNPIDYLGSSTRRGGGGD
The following text describes a protein:
Function:
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MAILEEIDDVDNMDFDPAEFDPRAVLTDATAHQESDGRGPINLISKAEHERREQAKKQQEQQQEQQQQANPMAQLQQMMDQMNQGGGMPPNMGQQGKPGTQVFDSEEFKNQEIQESDFKDWQIVYPVYFDKNKTVGEGRRVPLELAVENPLGQTIAEACKMLTLPSIYEAHKTHPKDWANPGRVRVQLKDDPALGLPPHSVKNKRHLFRLIAQYMKEHPTKEVTPYQGPVFQKIIQTNPEFPWNSKNLPPKPQYPRGWKMPEILPILSPALSHGEANNDMMEQMANQFMPKIPEAPPQQKVKKMKVRVGR
The following text describes a protein:
Function:
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Subcellular Localization:
Secreted.
Sequence:
MALTFKAAFLALMLALTRAAPFILWVSVILISHPDGDSALPDRCAGIEFDAITPDDKGQTFFFKGDHVWKGFDGDAQPSSQYFKELNGHVDAAFRMHNPENKGDHDHIYLFLDDKVFSYFEHTLEEGYPKEIQEDFPGVPTHLDAAVECPKGECITDSVLFFKGPDVHVYDIVTKTVKTKTWPHLPACTSVFRWLEHYYCFHGHNFTRFQPVTGEVTGNYPKDARRYFMRCPDFGHGGERTTLKCSDFKMDAITTDDTGRMYMFKGSNYMRLDTHRDGLHAFPITRSWKELTNGVDAVFSYNDRIYLIKGDQVYIYKAGAHFTLIEGYPKTLKEELNIEGQVDAAFVCPGQRTAHIIQGRKITYINLAATPREITLDAPLPFGDIDAAFCSSDGIKIFQGSNYYHYDSPMLLVMSRIAPIPLKVTSAMVGCED
The following text describes a protein:
Function:
Essential for both formate-dependent and formate-independent uric acid degradation. May be directly involved in the transcription of uacF in response to hypoxanthine, xanthine, and uric acid.
Sequence:
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAGTGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISKIFATMIDNMDQGVLVVDDENRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQMIREALSRHNSKKQVADELGIGIATLYRKIKKYELLNT
The following text describes a protein:
Function:
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
Sequence:
MTLLQREENIIRKGNIDKEFSEKIKAAGGDSLEYCFQCGTCTGSCPSGRRTPYRVRQIIRKANVGLKDEIISDPTLWMCTTCYSCQERCPRKVKIVDVVKLARNEAAKAGFMAPAHKAVGSFVIKTGHGVPINDATMELRKAVGLGELPPTTHQFPEALEEVQKIIKATGFDQLIGYNWETGELE
The following text describes a protein:
Function:
Essential for the fidelity of chromosome transmission. Required for the DNA replication block checkpoint. Replication factor C (RFC) complex has an essential but redundant activity in sister chromatid cohesion establishment. An RFC-like complex (ctf18-RFC) is formed where ctf18 replaces rfc1 in the RFC complex along with the association of dcc1 and ctf8. This complex is required for efficient establishment of chromosome cohesion during S-phase. Acts as a PCNA loader, loading PCNA onto primed templates.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEANEERCILLKYPHPSSDISSEYLLLELDDDLLKTLEENPEEEIVFKSDFDKKASVLCTSDKTYAVRQVVQSNSYLLFDELSPTDWVLNDTCYSFLEVERIYGFIFSDDKISYWDEDSVELKPISLTKDQFIRSVPASRNEVDSFLQKNFFMVKNEFLYRLSPSYICSIIDWIFVIAQQLHIDFASFEFKILKKPAMDDEFDWDSVICVLESISSPIKDNVLPKKFNIDLELTTFWYGRFLLEGINSISSDEFIQLWDNRLPYPCKGLPSLNLLKGYYFHDTPNTIQYLSGDQLPREPSRRFQSLFQLKSKWLYEELWSFVKDLALSKSRVEALILKYGRKQTSRDGVYINSRGTW
The following text describes a protein:
Function:
Regulates the expression of oprD which encodes the imipenem-specific porin.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTTRALDTANENPEQSGSWSGVLAIAVCAFALVASEFLPVSLLTPIANDLGTTEGMAGQGIAISGAFAVLTSLFISSVAGSLNRKTLLLGLTAAMGMSGAIVALAPNYFVYMLGRALIGIVIGGFWSMSAATAMRLVPANDVPRALALVNGGNALATVVAAPLGAWLGTLIGWRGAFLCLVPVALVALAWQWTTLPSMRAGARAPGPGNVFTVFALLKRPGVMLGMLASSLFFMGQFSLFTYVRPFLETVTGVHGAHVSLVLLVIGAAGFIGTLLIDRVLQRRFFQTLVAIPLLMALIALVLTVLGGWPAIVVVLLGLWGLTGTSAPVGWWAWIARVFPEDAEAGGGLFVAVVQLSIALGSTLGGLLFDRTGYQATFFASAAMLLIAAFLTILTARSKAPAG
The following text describes a protein:
Function:
Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor (By similarity). Required for SCF(TIR1) function. Modulates SCF(TIR1) function through its interactions with the CUL1 subunit. Represses photomorphogenesis by promoting HY5 degradation in darkness.
Sequence:
MANLQVSGILEKFQMTGKDKDYRYMATSDLLNELNKDSFKIDLDLEVRLSSIILQQLDDVAGDVSGLAVKCLAPLVKKVGEERIVEMTNKLCDKLLHGKDQHRDTASIALRTVVAQIAPTLAPSILVTLTPQMIGGISGQGMSSGIKCECLEIMCDVVQKYGSLMTDDHEKLLNTLLLQLGCNQATVRKKTVTCIASLASSLSDDLLAKATVEVVKNLSNRNAKSEITRTNIQMIGALCRAVGYRFGTHLGNTVPVLINYCTSASENDEELREYSLQALESFLLRCPRDISPYCDEILNLTLEYISYDPNFTDNMEEDTDNETLEDEEDDESANEYTDDEDASWKVRRAAAKCLAGLIVSRSEMLTKVYQEACPKLIDRFKEREENVKMDVFNTFIDLLRQTGNVTKGQTDTDESSPKWLLKQEVSKIVKSINRQLREKSVKTKVGAFSVLRELVVVLPDCLADHIGSLVPGIERALNDKSSTSNLKIEALVFTKLVLASHAPPVFHPYIKALSSPVLAAVGERYYKVTAEALRVCGELVRVVRPSTAGMGFDFKPFVHPIYNAIMSRLTNQDQDQEVKECAITCMGLVISTFGDQLRAELPSCLPVLVDRMGNEITRLTAVKAFSVIATSPLHINLSCVLDHLIAELTGFLRKANRVLRQATLITMNTLVTAYGDKIGSEAYEVILVELSSLISVSDLHMTALALELCCTLMTGKSCSENISLAVRNKVLPQALTLVKSPLLQGQALLDLQKFFEALVYHANTSFYTLLESLLSCAKPSPQSGGVPKQALYSIAQCVAVLCLAAGDKNCSSTVKMLMEILKDDSGTNSAKQHLALLSLGEIGRRKDLSAHAGIETIVIESFQSPFEEIKSAASYALGNIAVGNLSNYLPFILDQIDNQQKKQYILLHSLKEVIVRQSVDKADFQNSSVEKILALLFNHCESEEEGVRNVVAECLGKMALIEPEKLVPALQVRTTSPAAFTRATVVTAVKYSVVERPEKLDEIIFPQISSFLMLIKDGDRHVRRAAVSALSTFAHYKPNLIKGLLPELLPLLYDQTVIKKELIRTVDLGPFKHVVDDGLELRKAAFECVFTLVDSCLDQVNPSSFIVPFLKSGLEDHYDLKMLCHLILSLLADKCPSAVLAVLDSLVEPLHKTISFKPKQDAVKQEHDRNEDMIRSALRAISSLDRINGVDYSHKFKGLMGDMKRSVPLWEKFQTIRNE
The following text describes a protein:
Function:
Involved in cell separation.
Miscellaneous:
MISCELLANEOUS: Present with 22600 molecules/cell in log phase SD medium.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MISPISFLSSLLCLTYLTSALPILPKREVVTRVHTASTTNVVTDFYSTTTEVVIAPTVEFLISDSVTFTTTLIPQGVNPTAEPTTTITKVLLKKAEMSTSSQPTSTLQPSTIPQSTSSFQAESTLQAVSTQQTAMSVSAGTSEDVQQLATTSTSISSSPSPTTTSTSTQNIVSGVGEANVEGNTQSQHHSYQAAATSTLNQQTSTSIASQESTESTNTPTSSSTSSSTSSSTSSSTSSSTSSSTSSSTSSSTSSSTSSTQETAATTSEGSSSSSAAITSSPKAIAYSPYNDDGSCKSADAVSSDLTLIKSKGISKIRVYGTDCNSFETVQPAAVKLGIKINQGLYITSSGVDSIDDSVTTLIQYGQTNGWDVFDFITVGNEAINNGWCSVSDLISKISSVKSKLSEAGYSGQITTSEPPVSFENNPDLCKKSDIDFVGINPHAYFDTSASAETAGTFVKGQVELIQGVCGTSNVFVTETGYPSSGIQNGGNIPSTANQITAVQNILNEMDLDVTILSTYNDYWKAPGDYGIEQSFGVIEYFP
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MASFNSFPIPKQIVRSSSSSSSASRPRILVRSSMASTNSMLVFVPPHPLIKHWLSLLRCGQTPPLPFFVRIASRWSFLSSLKEDTTFHLRDHPLKACGCASATAENVYVELKDPKEYIGVGVVGEQMSSSSSEKVNLSRSMLQYNLLGKNLLALEQTFVALESLRMERDIMLQMRKLGATELFNTCLSRSRASSTTSCLPDTGTPELVDTTEEQQTFVPSTRKLRKKARRSSLMTGNDDQGSRTTWEGIDVPRVRKPSKYRKKRERISRNEAEMSQGVKIVADMERIRTKLEEESGKVASMSCWAEAAGMNEKLLMRNLHFGWYCRDELVKCTRSLVLFLARNYRGLGIAHEDLIQAGYVGVLQGAERFDHTRGYKFSTYVQYWIRKSMSMMVSRHARGVHIPASIIRTMSQIQKARKTLKTSQGIKYPADEEISKLTGYSLKKIRAANQCLKVVGSIDKKVGDCFTTKFLEFTPDTTMESPEEAVMRQSARREVHNLIEGLEAREKQVMVLRYGLQDYRPKSLEEIGKLLRVSKEGIRKIERRAMAKLRDQPKADNLRYYLNHEGINTAYASRPPHVRITQNRFFQAIIMQNEEGVVTELYIPRKCSATNRLITSKDHASVQLNIGHLDADGIYTGQFTTLALCGFVRAQGDADSGVDRLWQKKKVETKQL
The following text describes a protein:
Function:
Involved in the negative regulation of epithelial-mesenchymal transition, the process by which epithelial cells lose their polarity and adhesion properties to become mesenchymal cells with enhanced migration and invasive properties.
Subcellular Localization:
Nucleus.
Sequence:
MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGINRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEEIQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVVIPSDQVQKKIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPVSISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESNVLGATSGSLIAVSIESEPHQHHSLHTCLNDQNSSENKNGQENPKVLKKMTPCVTNIPHSSSATATKVHHGNKSCLSIQDFRGDFQNTFVVSVTTTVCSQPPRTAGDSSPMSISKSADLTSTATVVASSAPGVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINSLTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESGTSPTTSNHSRYVATDINLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQMAQPVGSAVNSAPTNQNVIILQPPSTTPCPTVMRAEVSNQTVGQQIVIIQAANQNPLPLLPAPPPGSVRLPINGANTVIGSNNSVQNVPTPQTFGGKHLVHILPRPSSLSASNSTQTFSVTMSNQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALASLNQSISQMAGQSCVQLSISQPANSQTAANSQTTTANCVSLTTTAAPPVTTDSSATLASTYNLVSTSSMNTVACLPNMKSKRLNKKPGGRKHLAANKSACPLNSVRDVSKLDCPNTEGSAEPPCNDGLLESFPAVLPSVSVSQANSVSVSASHSLGVLSSESLIPESVSKSKSAEKSSPPSQESVTSEHFAMAAAKSKDSTPNLQQETSQDKPPSSLALSDAAKPCASANVLIPSPSDPHILVSQVPGLSSTTSTTSTDCVSEVEIIAEPCRVEQDSSDTMQTTGLLKGQGLTTLLSDLAKKKNPQKSSLSDQMDHPDFSSENPKIVDSSVNLHPKQELLLMNNDDRDPPQHHSCLPDQEVINGSLINGRQADSPMSTSSGSSRSFSVASMLPETTREDVTSNATTNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQADIREVASKPSEASLLEGDPPFKSQIPKESGTGQAEATPNEFNSQGSIEATMERPLEKPSCSLGIKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTSEQTTVPATVNLTVSSSSYGSQPPGPSLMTEYSQEQLNTMTSTIPNSQIQEPLLKPSHESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPNSSNSVVPVSNPAHGDGLTRLFPPSNNFVTPALRQTEVQCGSQPSVAEQQQTQASQHLQALQQHVPAQGVSHLHSNHLYIKQQQQQQQQQQQQQQQQQAGQLRERHHLYQMQHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTDQSRSKTGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHHNHPQNHLNQDIMHQQQDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQQMVSQPSIVTRSSDMTCTPHRPERNRVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRVDHTVASDIRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNPVSSLRSMQSQAFRISQNTGPPPIDRQKRLSYPPVQSIPTGNGIPSRDSENTCHQSFMQSLLAPHLSDQVIGSQRSLSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGAINTRNSTLNIPFSSSSSSGDIQGRNTSPNVSVQKSNPMRITESHATKGHMNPPVTTNMHGVARPALPHPSVSHGNGDQGPAVRQANSSVPQRSRHPLQDSSGSKIRQPERNRSGNQRQSTVFDPSLPHLPLSTGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPPINANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFSNPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNSHLSNFNMTSLFPEIATALPDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV
The following text describes a protein:
Function:
Urea hydrolase involved in nitrogen recycling from ureide, purine, and arginine catabolism.
Sequence:
MKLLPREIEKLELHQAGFLAQKRLARGIRLNYTEAVALIATQILEFIRDGDKSVAELMDIGRQLLGRRQVLPAVLHLLYTVQVEGTFRDGTKLVTVHEPISLENGNLELALHGSFLPVPSLDKFPEVHEGVIIPGDMKYGDGSIIINHGRKAVVLKVVNTGDRPVQVGSHYHFIEVNPLLVFDRRKALGMRLNIPAGTAVRFEPGERKSVVLVNIGGNKVIRGGNGIVDGLVDDVNWTVLMETMERRGFKHLEDIDASEGIAGEDPRFTTMISREKYANMYGPTTGDKLRLGDTNLYARIEKDYTVYGDECVFGGGKVLREGMGQGIEQAEALSLDTVITNSVIIDYSGIYKADIGIKNGHIVGIGKAGNPDTMHGVQNNMLIGNKTEVIAGEGMIVTAGAIDCHVHFICPQLVYEAVSSGITTMVGGGTGPAYGTRATTCTPSPFDMKLMLQSTDSLPLNFGFTGKGNTAKPLELRHIVEAGAMGLKLHEDWGTTPAAIDNCLAVAEEYDIQVNIHTDTLNESGFVEHTINAFRGRTIHTYHSEGAGGGHAPDIIRVCGVKNVLPSSTNPTRPYTKNTVDEHLDMLMVCHHLDKNIPEDVAFAESRIRAETIAAEDILHDMGAISIISSDSQAMGRIGEVISRTWQTADKMKAQRGAIDPNMADDDNSRIKRYIAKYTINPAIANGFADLIGSVEVKKLADLVIWQPAFFGAKPEMIIKGGNIAWANMGDANASIPTPEPVISRPMFGAFGKAGSENSVAFVSKAALRKGVKELYGLKKRVVAVSNVRQLTKLDMKLNDALPEITVDPETYVVTANGEVLTCAPADSVPLSRNYFLF
The following text describes a protein:
Function:
ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MLHLFSKGLAFFWRKAEEEEREARERRDVKRPKTVQGVVTRFCPDYGMIDDSIFFTNDAVMSNAPLQVGQRVVALVEEDKISTGLKAVRVEIIPDTWEENSTCPSEIDSDIKTLIGNITSLNETGGHINQTTSFSFDVVCEAFKPCKGDWVEAEYVINPATWTTKAICVKPLRYKRIDKVRVSSLCGRTGVVDDSVFFTLDSLRLADGYIPQRYDLVNVVAVESNQSCYIWRALCMAPADKNGSSITPGITCSESYEHLLKDKEGLEVSKITNIGELKLGETKSMEVWIENKGKTTHHLISCKLGGWDKERQFYLEVPGSSQKSSTATIVSSVALTGINPGVESADFNNVGGCDSSFVSQTEKLSCEKVQNKDMEENTAESKRDISLPSGGKISIMVSCTAKNPGHCKELLLLCFSDCVIARHIEATVVTEEESWIAATEPFSQRKCQVISEHDKKAVVVLPMHKRVSRRQLPNFIGQYPLPDTLRRCVEKNLDILAFNPHLGEGLTLANYKAFFFTLLWLEEISEEQELKDLSLYGVILKKNGNFLVLEVPGVLEGRPSLYPGDKVILKTQGYTEQAIHYVAFITEIDKEDVTLKLNPAFEQAYNGEPMDVEFPLGRTTTRRCHFAVEQAVHLGEKVLFPERLTVQFPQIVKQWNDSEMPCSVQEESTTNGTKDDRAQNSKKKKMTKDKKTVTFSDMMTTAAQTRNKTATSDRKDCGFFNPMLNEHQKLAVKRILSGECRPTPYIIFGPPGTGKTVTVIEAILQIHYALPDSRILVCAPSNSASDLLCSRLHESNMLKPGAMVRVNASSRNEENLSEVIKYYCKDGEDIWQASRFRIIIVTCASAGMFYQIGVRLGHFTHVFVDEAGQASEPECLIPLGLVSEVTGQIVLSGDPMQLGPVIKSRLAIVYGLNISLLERLMCRPLYMRDEKAFGACGSYNPLLITKLIKNYRSHAALLTVPSRLFYHNELEICADPSIVNSLLGWEKLPMKHFPLIFHGVRGTEMREGHNPSWFNPTEAVQVMLYCCLLAKNITRAVSEMDIGVITPYQKQAEKIRILLRSMNLMGIKVGSVEEFQGQEYLVIILSAVRSNEASLGDEKVYLGFLANSKRFNVAITRPKALLIIVGNPHVLAKNPCFCALLDYSLENGVYVGCDLPQELENQRLNDELKRTAVRPDKSS
The following text describes a protein:
Function:
Catalyzes a syn cycloisomerization. Also possesses mle activity.
Sequence:
MPLHHLMIGTWTPPGAIFTVQFDDEKLTCKLIKRTEIPQDEPISWMTFDHERKNIYGAAMKKWSSFAVKSPTEIVHEASHPIGGHPRANDADTNTRAIFLLAAKQPPYAVYANPFYKFAGYGNVFSVSETGKLEKNVQNYEYQENTGIHGMVFDPTETYLYSADLTANKLWTHRKLASGEVELVGSVDAPDPGDHPRWVAMHPTGNYLYALMEAGNRICEYVIDPATHMPVYTHHSFPLIPPGIPDRDPETGKGLYRADVCALTFSGKYMFASSRANKFELQGYIAGFKLRDCGSIEKQLFLSPTPTSGGHSNAVSPCPWSDEWMAITDDQEGWLEIYRWKDEFLHRVARVRIPEPGFGMNAIWYD
The following text describes a protein:
Function:
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Subcellular Localization:
Nucleus.
Sequence:
MDSHAHLQWIQHHQQALRQRQEKLDDRRVQLVQRCRQIQSTQMMQHAQDELAQVMQQHGYQARLILTAMMNHHHEKETWNQFLHRHHITLQQFIGQFKRQRIPTWPPQFNNLDVKPPSHQAQLNLQHNHVHHWLGQLDDQLTMMEKEQWSDVTESSSGGESCDELDAADTAIVAQRTSFPTDVKQWYFHRGSIASRWTWIEFQKLRLEERLQHYTQMLEKLEDRHPVEAHCPTQLVRPERNTLTVSFKDIENFDSDLAVTIQQEYYRVFPYLCRAVRKCTQEQDKIPQEKEFFISFADFDTRHKVREMTTQKIGSLLKIRGQVVRTHPVHPELINGTFICLECQAVIKDVEQQMKFTQPVVCRNPACQNRSKFMLDVDKSIFVDFQKIRIQETQEELPRGSIPRSMEVILRAEAVEQAQAGDKCDITGTLIVVPDVSQLRTPGTTSEPASKRRTNDGYNNDGVSGLKSLGVRELSYKLSFLACNVTPVDAKFSGRDALGDEMTAERIKKQMTEHEWQKVYEMSSDKNLYQNLITSLFPTIHGTVL