lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
DNA-dependent ATPase, acting on dsDNA with a 3'-ssDNA tail, unwinding with 3'-to 5'-polarity. A minimal tail of 18 nt is required for activity. Also highly efficient on nicked DNA. Involved in the post-incision events of nucleotide excision repair, as well as in nitrosative and oxidative stress response and possibly in persistence in the host. Inhibits RecA-mediated DNA strand exchange; this does not require ATPase activity. When combined with UvrA greatly inhibits RecA-mediated DNA strand exchange.
Sequence:
MSVHATDAKPPGPSPADQLLDGLNPQQRQAVVHEGSPLLIVAGAGSGKTAVLTRRIAYLMAARGVGVGQILAITFTNKAAAEMRERVVGLVGEKARYMWVSTFHSTCVRILRNQAALIEGLNSNFSIYDADDSRRLLQMVGRDLGLDIKRYSPRLLANAISNLKNELIDPHQALAGLTEDSDDLARAVASVYDEYQRRLRAANALDFDDLIGETVAVLQAFPQIAQYYRRRFRHVLVDEYQDTNHAQYVLVRELVGRDSNDGIPPGELCVVGDADQSIYAFRGATIRNIEDFERDYPDTRTILLEQNYRSTQNILSAANSVIARNAGRREKRLWTDAGAGELIVGYVADNEHDEARFVAEEIDALAEGSEITYNDVAVFYRTNNSSRSLEEVLIRAGIPYKVVGGVRFYERKEIRDIVAYLRVLDNPGDAVSLRRILNTPRRGIGDRAEACVAVYAENTGVGFGDALVAAAQGKVPMLNTRAEKAIAGFVEMFDELRGRLDDDLGELVEAVLERTGYRRELEASTDPQELARLDNLNELVSVAHEFSTDRENAAALGPDDEDVPDTGVLADFLERVSLVADADEIPEHGAGVVTLMTLHTAKGLEFPVVFVTGWEDGMFPHMRALDNPTELSEERRLAYVGITRARQRLYVSRAIVRSSWGQPMLNPESRFLREIPQELIDWRRTAPKPSFSAPVSGAGRFGSARPSPTRSGASRRPLLVLQVGDRVTHDKYGLGRVEEVSGVGESAMSLIDFGSSGRVKLMHNHAPVTKL
The following text describes a protein:
Function:
May be a carbon dioxide/bicarbonate transporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSRPTFTILTILLQVLFVVIFAIFGEYGDDARPNHKRPNPGAAGINAVNIYYPMFQDVHVMIFLGIGLLLAFLRNHAYSSISYCFFAAAILCEWSTIINGVFWHIIEGGNDKFKIDLFSAINADFAAAVILISYCVVLGKISILQLLVMGVIELAVYVLNSWICFAKLGISDIGASITIHMFAAYFGLGVTRVLHSRDSEGNGKECSSYHNDVFCLVGTIFLWLYWPSFNACLTTDDVMRHRTVTNTYYSMLGACVMVFALSPMFRRDGKFNLSHVQNATLAGGVAIGTASNMIVQPWGSMLIGSIGGAMCTLGYVYLSPFLQKHCKMHDVCGVHNLHALPAFLSGIASAIASSLAAADEYGDATPSQQAGFQVAAMFVTIGISLLSGILTGFLIKLWIFEPMSTRQMFDDEDFWMVSKC
The following text describes a protein:
Function:
Participates in the control of the reentry into the cell cycle following pheromone treatment.
Subcellular Localization:
Vacuole.
Sequence:
MAATTASCISFSQFQRLKKLIDSPASKHKPMEFKGTSKDDLEDDLNSFFDCEEELFLSANKIFYSKLRVYQTVRHWSLKQNWSSMSLDQKRNFILHCHHELSSGELLRNSALYSILYIAAGAYDSVGSFEEHVHSISENVYLLREFDIPKTVYSLFIEWNRTRKHSFLDNSRDEGFLNLLLSLMFFFLTLNNTDKTWIHSIRSLNPPVLPTLVKLFIDITSDYQLNLDKVIHSSLKKLSFLIFKVCIRLWGSQSYLQEKKAGLAEVLNISTSQQKPKTTALDYEVFRHEMATKFSSFADSYYPVPLDREQAHILPTLNTDSFHKSSFISSTRLCSPENPSLLVNTAKTSKMSARREQFQTNQNLPFCFTPNLEKLTIPYSVTEAANVFQNKTKRTLAVEQLLSERELLRRFTLQQRLVADLHEFYNSVKGPAHSFETEDPVLKFVSQSYDDLFPYMDNFIQLAVQLFYHISKKVNCLYVEAFSSSDAVLQRIQDNAVVDSPTEELSEQAARNRKSNVKIEYTEDFATGFAISGEISHSINNLEFVLYSLSSLFLMMLKWFRLSHVLRFERLAFLLYENHFLEIFNRHLTEGDCNRNTEKDVKCVRGGFFSYSSKMYKYDRVSIPVITRASSSRNLLITMNCLRVLEKVCKYSNIRKEIIARSNLHENLKKLLAIPHDKLRLYALKVLKLSVPFLGLKWKQANMSIITQIYLNCSLDLRDSWMFHENGSDTYRSAQLQETFLAILIRFYHIRLYGKKCKSLYQFCILEEMRLKKSIEELAASNMMEYIPESLWSYSFERSDTGFFENEFAAMHINDIA
The following text describes a protein:
Function:
ATP-binding RNA helicase involved in mitochondrial RNA metabolism. Required for maintenance of mitochondrial DNA (By similarity).
Subcellular Localization:
Mitochondrion.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MFKLLIPNKYNYVIRPLVRFKSIKSPKSPKPKPTAKLSPNVFSSGKFSQLHNDTSTTNIESKITSFDQLKIFPSVREAMIKEIKSQYNLKGPRHSNIDEIDIKPTPVQIAAIRKINQTRKLKVPNKDLEGMDDAERIQFELQNANEIQKTKVFTVAAETGSGKTWSYLAPLLSKLKSDDMEFWKSDPEGYDNTRKKGQFVKSVILLPTNELVDQVYETLQRANSFELDHKGAPGNFTSFLELPENKTMNITTMKLGQGEAPVRLFRQLETKGPIDVLITTPGKIVAFSKLVNINRPFRVFANVKYCVLDEADTLFDDSFEKNTTDVITHFPKLLDLILVSATIPKVFEKKLSKLFPDQRSLIRVATPSLHKVPRNIKVMTIDADVAPYNGSKPRCLAQALYAISKDGTEPGYVKRIIVFVNEKSEVDGIVESMITKYKVRPEDIVGVSGSVNIRDRKDMLQPFLQPAELIENDDFGSKVKILVTTDLLARGLNFQGVKNVILLGLPRNSVDLVHRLGRTGRMNQNGRVFVIVDKKSKKSWVKGLGNAIIRGLRIG
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Subcellular Localization:
Plastid, chloroplast thylakoid lumen.
Sequence:
MASPLSSSTVVSHRLFFLHPSPLNRKFLFVKPKLPFNRTNSGDFRMRLHSTSSKTGTKELIHSCNSSIDSKLNTFEAGSKNLEKLVATILIFVQVWSPLPLFGLDSAYISPAEAVLYSPDTKVPRTGELALRRAIPANPSMKIIQASLEDISYLLRIPQRKPYGTMESNVKKALKVAIDDKDKILASIPVDLKDKGSELYTTLIDGKGGLQALITSIKKQDPDKVSLGLAASLDTVADLELLQASGLSFLLPQQYLNYPRLAGRGTVEITIEKADGSTFSAEAGGDQRKSATVQIVIDGYSAPLTAGNFAKLVTSGAYDGAKLNTVNQAVITEDGSGKVESVSVPLEVMPSGQFEPLYRTPLSVQDGELPVLPLSVYGAVAMAHSENSEEYSSPYQFFFYLYDKRNSGLGGLSFDEGQFSVFGYTIAGKDILGQIKTGDIIKSAKLIEGQDRLSLPVQNNNINEST
The following text describes a protein:
Function:
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Also belongs to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Subcellular Localization:
Nucleus.
Sequence:
MYLYNLTLQRPTSVYQSISGNFSGTKQVEIVLNHGRSLELIRYDENGKMQSVLYTEVFGIVRSIIPFRLTSGTKDYIIVGSDSGRVVILEYNSQKNQFDKIHQETFGRSGCRRIVPGQYLAVDPKGRAFMIGAIEKQKLVYILNRDSSANLTISSPLEAHKSNTIVFSMCGVDVGFDNPIFATISVDYTEEDSSSGGGGGGSIEEMMDEDIGKKKKLLTYYELDLGLNNVVRKWSDQVDDSANIVMTVPGGTEGPGGVLVASEDYIVYRNQDHAEVRSRIPRRYGSDPNKGVLIISHSSHKQKGMFFFLVQSEHGDLYKITLDYQGDQVSEVNVNYFDTIVLANCLTVLKNGFLFAASEFGDHTLYFFKSIGDEEEEGQAKRLEDKDGHLWFTPRNSCGTKMEELKNLEPTSHLSSLSPIIDFKVLDLVREENPQLYSLCGTGLNSSLKVLRHGLSVTTITTANLPGVPSGIWTVPKSTSPNAIDQTDKYIVVSFVGTTSVLSVGDTIQENHESGILETTTTLLVKSMGDDAIIQVFPTGFRHIKSDLRINEWRAPGRKTIVRASANQSQLAIALSGGEIIYFELDQASNLIEIIKKDLRRDIACIEISPIPKGRNMARFIAVSDWEGPIRVLSLDRDNCLGQVSMLDTDKVYIESLSIIEMQLNEMGIETKKSQSQTGQTTTTTTSTSSASSSVTSGGSLFLFVGLKNGVVKRATLDSVTGELSDIRTRLLGRKPVKLFKVKVRGSNAMLALSSRVWLNYINQGKLDIVPLSIEPLENASNLSSEQSAESIVATSENKIIIFSIDKLGDLFNQETIKLNATPKRFIIHPQTSYIIILETETNYNTDNIDIDKINEQSEKLLLEKQKELQQEMDIDDDDQNNNNEIEPFKKLFKPKAGKGKWKSYIKIMDPITHESLESLMLEDGEAGFSVCTCSFGESGEIFLVVGCVTDMVLNPKSHKSAHLNLYRFIDGGKKLELLYKTEVEEPVYAMAQFQGKLVCGVGKSIRIYDMGKKKLLRKCETKNLPNTIVNIHSLGDRLVVGDIQESIHFIKYKRSENMLYVFADDLAPRWMTSSVMLDYDTVAGADKFGNIFVLRLPLLISDEVEEDPTGTKLKFESGTLNGAPHKLDHIANFFVGDTVTTLNKTSLVVGGPEVILYTTISGAIGALIPFTSREDVDFFSTLEMNMRSDCLPLCGRDHLAYRSYYFPVKNIIDGDLCEQFSTLNYQKQLSISEELSRSPSEVIKKLEEIRSQKLL
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MDIISQLQEQVDLIASLAFNTIGTLQRDAPPVRLSPNYPEPPANPTEDFVEQPKLMSAALVKAAKQFDALVAALPLAEGGEEAQLKRIAELQAENDAIGQELQRQLEAAEKELKQVQELFSQATDNCLNLKKPD
The following text describes a protein:
Function:
May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Is concomitantly relocalized into discrete nuclear bodies at higher expression.
Sequence:
MSSKQEIMDDQRFRRVSKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHSTTEDLKRFYDLSDSDSDLSDEESKVLDEKRVKEKKKQTKKETKSKTPIEEKKKETKKTDQKDSINKNDLNNSERIQKMKNSHKSPKIDSEVSPKDSEESLQSRKKKRDTTDLSVEASPKGKLRTKDPSTSAMVKSSTVSGSKAKREKQAVIMAKDNAGRMLHEEAPEEDSDSASELGRDEESEGEITSDDRASADDDENEDEEEEEDGEEEEEEEEEEDESDDESDSGPDLARGKGNVETSSEDEDDLADLFPEEPGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVVFSVKIYPSEFGKQRMKEEQIQGPVELLSIPEDAPEKDWASREKLRDYQFKRLKYYYAVVECDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEPKDAASEVDLTAYKPKYFTSAAMGTSTVEITWDETDHERITTLNRKFKKDELLDMDFEAYLASSSEDEEEVEEAPEGEDGVSIEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKKKQKALAEEASEDEIPSDVDLNDPYFAEEVKKIGIKKKSMKSAKDGATSEEETELEKQKAEMALLVMDEEEDSKKHFNYDKIVEHQNLSKKKKKQLMKKKELLEDDFEVNVSDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARHREQKEERLIQAVERAQQDTGKPAQKQPMDPALSMLIKSVKNKTEQFQARKKQRIK
The following text describes a protein:
Function:
Abscisic acid receptor. The GDP-bound form exhibits greater abscisic acid binding than the GTP-bound form. Required for seedling growth and fertility.
Miscellaneous:
MISCELLANEOUS: Has both a topology similar to GPCRs and a GTP-binding/GTPase activity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSYGWAIYEGTVVIASLSLLGWAGLWFLNRRLYKEYEEKRALVQIIFSVVFAFSCNLLQLVLFEIIPVLSREARMINWKVDLFCLILLLVFMLPYYHCYLMLRNSGVRRERASVGAFLFLSAFLYAFWRMGVHFPMPSADKGFFTMPQLVSRIGVIGVTLMAVLSGFGAVNLPYSYISLFIREIEEADIISLERQLIQSTETCIAKKKKIILCQLEVERNQGSEENQKRSSFFRRIVGTVVRSVQDDQKEQDIKILEAEVEALEELSKQLFLEVYELRQAKDAAAYSRTWKGHVQNLLGYACSIYCVYKMLKSLQSVVFKEAGTKDPVTTMISIFLRLFDIGVDAALLSQYISLLFIGMLIVISVRGFLTNLMKFFFAVSRVGSGSSSNVVLFLSEIMGMYFLSSILLIRKSLRNEYRGIITDVLGGDIQFDFYHRWFDAIFVASAFLSLVLLSAHYTSRQSDKHAIE
The following text describes a protein:
Function:
Integrin ITGA4/ITGB7 (alpha-4/beta-7) (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin ITGA4/ITGB7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Also interacts with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involve the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Integrin ITGAE/ITGB7 (alpha-E/beta-7, HML-1) is a receptor for E-cadherin.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
PGVSISFESHCRSPEKSEGEAGDRRGQCNHVRVNQMVDFWVTLQASHCLPEAHVLRLWALGFSEELTVELHTLCDCNCSDAQPRAPYCSDGQGDLQCGICSCAPGRLGQLCECSEADLSSPDLESGCRAPNGTGPLCSGKGRCQCGRCSCSGQSSGRLCECDDASCERHEGILCGGFGHCQCGVCHCHANRTGRACECSESVDSCVSPEGGLCSGHGDCKCNRCQCLDGYYGALCDQCLGCKSPCEQYRDCAECGAFGTGPLAANCSAACADVNVTLALAPNLDDGWCKERTLDNQLFFFLVENSARGVILRVRPQEKGADHTRAIILGCVGGIVAVGLGLVLAYRLSVEVYDRLEYSRFEKERQQLNWKQDSNPLYKSAVTTTVNPRFQGGNKQSLSLPLTQEAD
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Sequence:
MAPKVFRQYWDIPDGTDCHRKAYSTTSIASVAGLTAAAYRVTLNPPGTFLEGVAKVGQYTFTAAAVGAVFGLTTCISAHVREKPDDPLNYFLGGCAGGLTLGARTHNYGIGAAACVYFGIAASLVKMGQLEGWEVFAKPKV
The following text describes a protein:
Function:
Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
Sequence:
MAARNTARKRAFQILFEGDQRGADVLTVLADWVRHSRSDTRQPPVSEYTMELVEGYAGRAERIDELIAQYSVDWTLDRMPVVDRNILRLGAYELLWVDATPDAVVLDEMVQLAKEFSTDESPAFINGLLGRLKELKPSLRRE
The following text describes a protein:
Function:
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Sequence:
MFPQKITLWLYPLGLFANLFFGTAFCVQWSLTRKKGYSVVPKIFWYLSGTGAVFMICHGFIQSQYPIALLHSFNLIIYFRNLNIASLNPLPVSKIASLLVSVATAITVSFAIGTRYLPHMTWMASPNILHLNLPEASLSWQLIGCIGLTIFSLRFFIQWFYLEYKNQSALPAPFWKASLLGGSICLLYFLRTGDLVNVLCYGCGLFPSLANLRIASREAFRKPFSNSCFISAGEHSGDTLGGNLLKEMHAKYPDIHCFGVGGPQMRAQNFHALFAMEKFQVSGFWEVLLALPKLWYRYQLLYRNILKTNPRTVICIDFPDFHFLLIKKLRSRGYKGKIVHYVCPSIWAWRPSRKTVLEKYLDLLLLILPFEQNLFKDSALRTVYLGHPLSETIKSFSPNLNWKDQLHLPTDKPFIAAFPGSRRSDILRNLTIQVQAFQASSLASTHHLLVSSANPEYDHLILEVLQQNRCLHSHIVPSQFRYELMRECDFALAKCGTIVLETALNLTPTIVTCQLRPLDTFLAKYIFNIILPAYSLPNIILGRTIFPEFIGGKKDFQYEDVAAALNILKTSQAQEKQKDSCRDVYQAINESASSMKECLSLIFETAS
The following text describes a protein:
Function:
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacc-1 itself) and represses transcription of acid-expressed genes (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSTPAQENGTVNGANAAPAPAPAQTTPTPAPATAATPTTAPAASANGTAANAMKPEASSNSSNSASNGTTPAPSTTPTTASNSSAPAAAQDESLVCRWAECNERFTSAEVLYEHICEKHVGRKSTNNLNLTCQWNSCRTTTVKRDHITSHVRVHVPLKPHKCDFCGKCFKRPQDLKKHVKTHADDSVLVGRSPQDQNGGMNGAYRAQAPVHKAPSGFYDHNGHMRGTNQVPFGQPHQNGQASYYHAQYPASQPYHAPMYYPAQTMGGQRNDFTGHQAAPFDARKRQFDDLNDFFGSVKRRQINPTSYESVGRALMPLHAPLGLHSGGLATEYMAQPPHTLGMASAHHPLTQHYYLPPMPNLRTKEDLQQMDHFLEQMQATVYENTAVDMRHHSPTYATRPSIDPYHGASLASPLSATSPHSAGTPAVTPTPSNMSYTSGHSPSTSSTSLSPTSRHSSTPSVSYPTLPSRPGLPYPSTSGLGSNFTHNERRLSGGVLQSARRAADEADRAPTPKASEQATVSSPSEDSETGDVNGPETYDDWLQHMRVIEYLRQGIRARLERQDFDEDDTSRIDPMVLESSDRNQQQRNQQQQQQKSPNEPTAAGPSAPEKPLYPVLPRIN
The following text describes a protein:
Function:
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
Subcellular Localization:
Cytoplasm.
Sequence:
MLTYDNWEEPTITFPEDDPYKGALSVLKWAYGHYGDQLVYACSFGIEGIVLIDLIYKVKKDAEIVFLDTGLHFKETYETIERVKERYPGLNIILKKPDLTLEEQAEEHGDKLWEREPNQCCYLRKVVPLREALSGHPAWLSGLRRDQGPSRANTNFLNKDEKFKSVKVCPLIHWTWKDIWRYTSRNELDYNPLHDQGYPSIGCAPCTSPAFTAEDLRSGRWNGMAKTECGLHE
The following text describes a protein:
Function:
Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).
Subcellular Localization:
Mitochondrion.
Sequence:
MSRFWHFKKFYFTSCYSMQRMRGKIFKNEPLVPMNVTSEHEQVQSISKEESRSLSSNDLNLSADSELQLESEPEIESEQLKNHEDVYEIIRSMVLAADTTLPRLSNNSLTGIYNHWKLNPNDDLPLYNPTKYTPYEFHSQYNQDRSYIITPRLSVTKLLVSSWCELRSFYQVYSGSVRLPSTKAMTQGTKLHSKLEAEVHPEIDTTEIEQFLISNAMSLRELQTTVPAEEETVVIDLGEVEQLAVDWAEMLIERLFSLIMGAEAREILLHGYLNLKNRSFVTNKDEIRESSSVLVSGIVDYIKLQNVTNPSDGTLFDDIHGFVDSAFDQVDNVPLVDLSQFLPEAKQILQNYDFRLTFTDVKTRSARQIPRQESVLEAAKFQTFYYRHFFHLLSRDSRFTYFSLIENAERRGHDVDKPLSILTTISLLRKHYHIFFKDFVKLANGEPIGFSPFDDSAKSIPYDFVSMFQSSDEFSLANPNHNHFLEQISAIDGIEYDSILSPLLKVWKTPPTLRYLAARASQLFNVFNENIGDITSVEYRYNKTSELLSEKVYDYNFSEFQAEVESASKFWNGEREVIPTEDLSRCSYCEFQSKCMVAGGKTTEAVEKKTIGPKIRQFLNECESSSKG
The following text describes a protein:
Function:
Probable alpha-1,2-mannosyltransferase involved in the N-glycosylation pathway. Probably involved in glycosylation of the TNF receptor grnd, regulating its ligand affinity. Required for normal epithelial growth and architecture. Suppressor of JNK-dependent intestinal stem cell proliferation.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAPPAARARYIANKADNQILSKKPPKRPGLNGNNKTKEATPAGKKKDKDAKKRNQPTSGGQEKGLPNPIMPSVQTAFKTFVSARLCSAIWAYIADCDETFNYWEPLHYIINGHGLQTWEYSPQFGLRSYTYLLLQGVPGYFYQKLFNPSPILIFYMVRCMLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQLFSVGMFVSSTALLPSSFSMYFGCAALAAWWQQNYCFAIFLTAISALLGWPFAALIGIPLVLEMLLRQRDWKTFVQWTLISGATVAIPMIAIDTSYFGKLTFAPLNIVWYNVFTSHGPNIFGTEPLSYYIINGFLNFNIIWLLALQLPIMLVIDYLIVPAKSKSTLNFPHYISLAPLYLWLLVFFAQPHKEERFLFPIYPLISLCGAITVDVYQRIFFRMKSVVFKIKAGVHYLDHSMFIAILVMVTSTLLGLSRVFALYRNYHAPMDLMLELNQFKATPQYDPDVIYNVCIGKDWHRYPGSFFFPAKNFRLRFLKSEFRGMLPAYYDEGQNATKVVQPYFNDLNQENEHMYFDYDRCDFLVDFDEGKYTALEPNYSKRSKDWSVMKSLPFLIPEKSHKVLRAFYVPFLTDNHIQYGDFNLLKRKTKRNGR
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MNIQGMALHGHMKPVTMIKFNREGDLLFSTAKEPNVSVWYTKTGERLGTYDGHSAISACDVNNYSTLLVTGGMDFKAKLWCVETGEELANIMLRTPARAVGFSHDDNLLMVSTSRKMGQKSAVQLYNLPFLPPKDGYSIHPVNTVFNPCTEFVSENDDVTFAIWGPTNDTIYYSTSDGSVAILDVETMSTVCTHKPHEETINRISFDSNYYTLITASKDKTARLLDSRDLSVVQTYTSDVPVNDASISPRGDHVIIGGGMDAQDVTTQGGQTTFEVKFYHKVHEKQLGQVRCHFGTINSVCFFPDGRGFASGAFDGLVKLHRFDDKYSSTPGAIPLWTPEGI
The following text describes a protein:
Function:
May be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV
The following text describes a protein:
Function:
May play a role in the regulation of the slug-fruiting body switch.
Subcellular Localization:
Cytoplasm. Note=Localizes predominantly to the cell periphery, but is also found in the perinuclear region in some cells.
Sequence:
MGKKDKNVSVEEEVDEAEIEKLAAENANKPAPQLTKEDLDAMDDAEPGTSRLALIGKMIKKVSIGTDISNISMPGSFILAKSTLSYFSDNFSSFFGELLKANKIDNELERMLQVQRYLFTTLKETEDTTRKPLNPILGETWQANIHVKDGDGNDVTDNYFFAEQISHHPPISSSTVYNKKEGVNCTFCLPVRSQFMGTYVKISFEGESHITFEKYDEKFTFVAPPMAIRIFRSFSEYVGKGILKSDKNDYLIKSTYTSKPLFGGVYNGFESKVYKGKEKLYKIKGTWSGDMKITNLKTNETTPFFTRPTESAKVVFPDDGNTLPTDSSVVWKGVFDASKKDDVKGMSQEKVKVEEEQRKLAHHRKNADEWKPVHFNKIDGRWQLVNLKD
The following text describes a protein:
Function:
The dimeric enzyme acts as an E1 ligase for SUMO1 and SUMO2. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2. Functionally redundant with its paralog SAE1A (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MDGDELTEQETALYDRQIRVWGAGAQRRLSKSHVLVSGIKGTVAEFCKNIVLAGVGSVTLLDDRLVTTEVFNANFLILPDENAYVGKTVAEICCDSLKDFNPMVHVSIEKGDLSTLGVDFFEKFDVVVIGYSSRATKKAVNEKCRNLAKDVAFYTVDCRGSCGEIFVDLQNYKYTKKKLDETVECELTFPSFEEAVSVPWKPMPRRTAKLYFAMRVIELFEETEGRKPGECSLSDLPRVLKLKKELCEGNSVSENHIPDILLERLVSNNTEFPPACAIIGGILGQEVIKVISGKGEPLKNFFYFDAEDGKGVIEDLSHKL
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MDQATKVAEAEGKGKGFGFPNGALRKHHHRPPAPAEAEFLYRECLKNHAASLGGHALDGCGEFMLSPTADPADPTSLRCAACGCHRNFHRRLADPPSHRHRGHPRDEEDDERDGVEDEDEDEGEDEDEDEEEVGAKIDGRRDRPRPLRGSASPPAFFSSAPHMLLALSAGLPGSPGTIPVRPVAAPTAAAAPVAAVGAPAAEAAQPRKRFRTKFSPEQKGRMQELSERLGWRMQKRDEGLVEECCREIGVDKGVFKVWMHNNKHTFLGLARRGDPASRSARSEGGIGGGDVSQPEGSGHANGADEGDGGHGHVVNGSLSSS
The following text describes a protein:
Function:
Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs. Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
The following text describes a protein:
Function:
Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. May act by regulating the GPI-GNT complex; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MNLNTNPKVIKNIPFQMARMSKRQLFAASGIPQDRKCKKQQNQAGRFSICHVTPDQQGAVTGLSPAAAAGHKPTGKTEVTWFYRLSTMATGVDQAVGMGLVLFSLALFSYYSVWVVVLPFMDGDHMLQQYFLPREYSVILPGIAAVVLLLMIGAFTAAVVWMNHKPKKVD
The following text describes a protein:
Function:
Secondary mitochondrial glycine transporter required for the biosynthesis of heme at high glycine concentrations. Imports the precursor glycine into the mitochondrial matrix, where it is condensed with succinyl-CoA to produce 5-aminolevulinate (ALA), the first step of heme biosynthesis.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MSEEFPSPQLIDDLEEHPQHDNARVVKDLLAGTAGGIAQVLVGQPFDTTKVRLQTSSTPTTAMEVVRKLLANEGPRGFYKGTLTPLIGVGACVSLQFGVNEAMKRFFHHRNADMSSTLSLPQYYACGVTGGIVNSFLASPIEHVRIRLQTQTGSGTNAEFKGPLECIKKLRHNKALLRGLTPTILREGHGCGTYFLVYEALIANQMNKRRGLERKDIPAWKLCIFGALSGTALWLMVYPLDVIKSVMQTDNLQKPKFGNSISSVAKTLYANGGIGAFFKGFGPTMLRAAPANGATFATFELAMRLLG
The following text describes a protein:
Function:
Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MDNLRETFLSLEDGLGSSDSPGLLSSWDWKDRAGPFELNQASPSQSLSPAPSLESYSSSPCPAVAGLPCEHGGASSGGSEGCSVGGASGLVEVDYNMLAFQPTHLQGGGGPKAQKGTKVRMSVQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQTLKYTIKYIGELTDLLNRGREPRAQSA
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MTEEEVKSDPEFQLKAIEKAYEQSSQQLNQLESVLQKFSTNFQSQEHSLTELYQKISKQQGIHRNIVKVRDCINEIQNKLTSTEQLSPILKTNIESNFDAYMEAMNKAIAAKKFLNRFQFNDAYNERMAITKLIEAAQRTILIYFIKLAHRSATPVLLSNFAFKDGKFVLTEKLYENPIYPVAEELLRMMKRMAEVLDITLCEDQYKEYQNARIDAINESISPILDASKKRVLQAQTLDIIDLPNYKPKEHPIHTIGYLVSFFYKRELAFAKAIFGEKYKNPFVNSFTPLFNTFKSICHSVMFANVQSPIDILFDVDLVSTIVDVLESEVNEDEFSMFAVQLAQMSHMFHSGIERVLSAYKSAVQHHDPDNIPASGGVTANVSNVIIFLKKLSIYKKGIEQVGGLSFDQFAPAVLAAMFKNNMEKATRYNDDILKQLFLMNNAHYALMQIEASPELATITPQEFKDTLEKTMQDAQKVYMNETWNAAFQILSYDKAFDGFKKGDKLNTQQKKIIKNKFKKFKEAVLDIQQKHNTYCLKNTKLMEPIMNEAIQKTHSKFEPFYMRWHDSGFASHPEKYTAVQPSTLEGIITRLYGAKKIRKTSV
The following text describes a protein:
Function:
Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MIISASTDYRAAAKAKLPPFLFHYIDGGSYGEHTLRRNTDDLADIALRQRVLSDMSELSLETELFGEKMALPIALSPVGLTGMYARRGEVQAAQAAEAKGIPFTLSTVSVCPIEEVAPSIHRPIWFQLYVLKDRGFMKNVLERAKAAGVKNLVFTVDMPVPGARYRDMHSGMSGPNAAMRRVLQAMAHPSWAWDVGLLGKPHDLGNISKYRGSPTKLEDYIGWLGANFDPSISWKDLEWIRDFWDGPMIIKGILDTEDAKDAVRFGADGIVVSNHGGRQLDGVLSTVQALPAIADAVKGDLKILVDSGIRTGLDVVRMLALGADCTMLGRSFIYALAAQGRAGVENLLDLYEKEMRVAMTLTGAKSIAELSRDSLVKR