lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Possesses intrinsic histone acetyltransferase activity and acts as a positive regulator of grain weight, hull size, yield, and plant biomass. Regulates postitively grain weight and yield by enlarging spikelet hulls via increasing cell number and accelerating grain filling. In vitro, catalyzes the acetylation of histone H4 at Lys-6 (H4K5ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac). Involved in the regulation of plastochron (the time interval between leaf initiation event).
Miscellaneous:
MISCELLANEOUS: Over-expression of GWA6A enhances grain weight and yield by enlarging spikelet hulls via increasing cell number and accelerating grain filling, and increases global acetylation levels of histone H4.
Subcellular Localization:
Nucleus.
Sequence:
MVETTTMMKVLVRVREFDVEKDLPAVEELERRCQVGLSGDMAAVHDHADDGDGAAAKEKKKTKTKTKKKKASMSLCVEQIGDPLARVRHAPEHVMLVAEYGEEEEKKKVVGVIKACVKTVSRGGKQEKPFVKVANLLGLRVSPSHRRLGIGTALVRRAEEWCVARGAEHATMATTESNAASLALFTGRFGYAPFRRPEFIGHPVHAHRLPVARGHRVFQLPPEVAAAAYARLLPPQDAEFLPADMPALLAHKLTLGTFVAVAADGASFAVLSVWDSTRSLSLRVSGAPALLRASLAALRALDRGAPWLHLPSIPDIFRPFGAYLLYGLRMSGPDGPALLRSLCHHAHNVARKNPACAVVAADISPDDPAAAAVPRWRRFCCDEDVWCIKNLNPDEHDADDWAAPPPPPGRHLFVDPREF
The following text describes a protein:
Function:
Mitochondrial RNA-binding protein that may have a role in mitochondrial translation.
Subcellular Localization:
Mitochondrion.
Sequence:
MASSCSQALRHHACKSSKILRIHLQKSWTNRSFAAYQQPDVSSQEEIVIPKKKTWSKEAVLQALASTVKRDPTASDYRLQDDSFLTPKTASDFKLFCRSQESGRNAAKYFINKYPKYFEKDYAQPHIPCLMPETLDAQLEDVSEAALKERIQLRKVKAAVDLYDQLLQAGTSVSLDLTNDLLDLICLYGEADPVQETFEAEQRSEEMEDIQDETQTKKGRSPKASDLLKTSWKENNNAERIFGLLSEPNTRSYSALIRGMVKHAAYTQAFSTYTDLLNNRLKADVHIFNALLAAVPAVRPKYNEKWELILDLLKQMAEQKVKPNLLTLNAILKSLRRCGALGRSQAFPVISEMKVLSIEPSLASYNHLLAIFYRSGAQVQTPTDVLVEVMNEVSGKSFTPQDPDDAQFFTTAMRVCLDTKDMEQAYRVHELLGVGDNWRFMGSDFQQSIYYAWFFSLLCMMENIDVVMKWYRDLVPSVYYPSSNAMSDLLRALDTDSRLDLIPKIWKDMKQLGHGNRQQLVEEVLTLMAREKHCPEVQESFADCALDIMKMYDTNERGKVIMSWTASSLSDVTTILLAANRKQEAWEMLKLFRTHNRVPSAELLNQFVTCVKEAGQVSQAVELVQISAAFCLSETPKLIQRVQQEFELSEEHKNILSDLEIQTFNGD
The following text describes a protein:
Function:
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination.
Sequence:
MSLDTFTSPAPRNRRVSRLSSGNKVRSAFKSPLRSPAASGPPGSSTTCSPLSSLISPIAERRGTFSQKRRRPSLAFNSSLKVKSPKVEVTEQDILELEAKITIQLKEINDLETEEGIKEEDLNIHIDKLHEYNEVKDAAQLVIGRLALQLQTTTRQLYPKFGLNFED
The following text describes a protein:
Function:
Peptidoglycan-recognition protein probably involved in innate immunity by binding to peptidoglycans (PGN) of bacteria and activating the immune response.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MFEENNSPTTDNSLWTLQGRQRASPAQRLHNLTSAGSSTSSSGLPLPQNIFTNPAIQPSSVINLNHSTDVVIGPMTQYQGPVSIYYMDYMEAHAMQTAAGINSNNANGNGNANRSRDKSPSRRVTRNTILLITLILLVLATGLIVLYVELNRPKPELPSNKAIYFGNNYDHQTFPNLGNGHLVVDREQWGASKNSHGLTIPLKRPIPYVLITHIGVQSLPCDNIYKCSIKMRTIQDSAIAEKGLPDIQSNFYVSEEGNIYVGRGWDWANTYANQTLAITFMGDYGRFKPGPKQLEGVQFLLAHAVANRNIDVDYKLVAQNQTKVTRSPGAYVYQEIRNWPHFYGCGMDEAPACGIELGMKTESWDAKQ
The following text describes a protein:
Function:
Probably acts as a transcriptional regulator. Required for the specification of the tarsal segment. Also involved in antenna development.
Subcellular Localization:
Nucleus.
Sequence:
MASTSSSSSSAASGGSSPHLCLRWNNYQSNLTSVFDQLLQNETFVDVTLAADGHAIKAHRMVLSACSPYFQHLFFDNPCQHPIVILKDTRWPELKAIVEYMYRGEISVAQEELTSLLRVAETLKIRGLSELNSDRHAAAAAAVTADDRSESSPLIPHHPTAGPSTSSSSSSATAAAVRRQTDSPTWHHHHQIHHQQQQQPAWPGHVMDEEMATTPTPSPTPAPASRSSGVKRRRISGSDSPIGGASSPAAASTPGMHHQHHEEASLDHHDGPLSLVGHQQHQAPPPPPPPHSPVASSASLAPQALTQAPPPPSSLHQHPLAHSDDLDIKPGIAELIREEERARMLEGTHPWLTASPSVLSESLVQWRSKAPSWSKETLQEAINSIVTQKMRFTQASSHFNIPKGTLYDNILGKSKRMLVLDELGLDAQDEEAVLDFCCETSVMPYNRRTNKSLESIVAFVEKLKQSKGQPSFKLGNLMGFRWWWAFCKKHNIVSLFYVKNNNNNKSSKNKNNNNNNNNNNRSSPSSASSASSGSSNNNNLSPSPPDELIPENLSKPFEEELPVGGGGGNHMTVAAAAAAAASAFRSINNNNIHLSQAFQLSHAFLLQQQRQNHRHNLRSRTHSVDHDHGDDSDPEPENLSVHRG
The following text describes a protein:
Function:
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
Sequence:
MSLLIIVESPSKAKTIAGYLGKEFRILATLGHVADLPKTTLGLDLKNRFEPEYVILPGKKKILSEIIKTAKQSQKVFLATDPDREGEFISAYIRDRLQKKSNVFRIRFTEVTKQAILNSLQNPDTINEFLVDAQKTRRIGDRLIGYFISPVLWKQIGPGLSAGRVQSVALKWICEREEEIRNFKIEIYYNILLHGTDQKGIVGIFSRTGDRIFSKEKADQILQNVQKEKEFRISEKKETLGKLFPPPPFQTASLQQEAFKKLRFSSKKTMSLSQRLYEGMDLGNGQRNGLITYMRTDSVRLSSEFVERARSWILSELGETFASPLERKIRKSAKKIQDAHEAIRVTDPFLTPKEIKKFLGKEEAALYDLIWKRTISSLLPAEEFIKIEYSIFAAGECFQLETKKTIFPGYKILNEADVKTNPSWEKGELFILQKVECEKKQTEPPSRYSEGTLVAKLEKQGIGRPSTYATVSETLLKRKYVYEEKKFFYPFSLGEKVNFFLQSSFGELFREKFTAELESDLDRIEKKEIDSNSILNRLWLDLQTQIQNSKFILFQKEWATVLQKKKETGWGICPVCRNGILQKKKSSRKKEFYQCNRFPDCEFVSYELPESLE
The following text describes a protein:
Function:
Senses the quorum-sensing autoinducer CAI-1 ((S)-3-hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to LuxU and LuxO.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIVSMDVIKRVYQYAEPNLSLVGWMGMLGFPAYYFIWEYWFPQSYENLGLRCAAAVLFGGLVFRDSMPKKWQRYMPGYFLFTIGFCLPFFFAFMMLMNDWSTIWAMSFMASIFLHILLVHDTRVMALQALFSVLVAYLAVYGLTDFHPTTLIEWQYIPIFLFTYVFGNLCFFRNQISHETKVSIAKTFGAGIAHEMRNPLSALKTSIDVVRTMIPKPQTAAHTDYSLDAQELDLLHQILNEADDVIYSGNNAIDLLLTSIDENRVSPASFKKHSVVDVIEKAVKTFPYKNAADQHSVELEVHQPFDFFGSDTLLTYALFNLLKNAFYYQKEHFSVCISIEQTSEHNLIRVRDNGVGIAPEMLEDIFRDFYTFGKNGSYGLGLPFCRKVMSAFGGTIRCASQQGQWTEFVLSFPRYDSDTVNEIKTELLKTKSLIYIGSNQAIVRELNQLAVEDEFGFTAISAQQAVRRQDYEFEFDLILLDLDDATAQGELLPKLEGTLSFAEGCIGYVYDPGKTYAVNINRYLRIQPISIHSILRKPRKIIERLLFEQESLSMNRNVIPLQKSRHERRILVVDDNQSIRTFTAILLEQQGYEVVQANDGSEVLKHMESQNIDLVLMDIEMPNVGGLEATRLIRNSEHEYKNIPIIGYTGDNSPKTLALVQTSGMNDFIVKPADRDVLLNKVAAWV
The following text describes a protein:
Function:
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Membrane; Peripheral membrane protein.
Sequence:
MESSLLTSPAAISRLAATRTLNCNCSPVISQFHRHFSTRPTQFLLLSQLARRHLRAVCNSEIRGLNRFGPVLISRSLGAASLRPVRKDLRSVSSSAASFAANGGGNDGSGDGATDGGKENLSVVAETGEDISALSSEVIILDVSGMTCGGCASSVKRILESLPQVSSATVNLTTETAIVWPVSEVKVVPNWQKQLGETLAKHLSTHGFKSNVRDSRRENYFEIFEKKMNAKRIQLKESGRGLVVSWALCAVCLVGHLSHFLGAKASWIHAIHSTGFQMTLSLFTLLVPGRQLIIDGLKSLIKGSPNMNTLVGLGALSSFAVSSMAALIPTLGWKTFFEEPVMLIAFVLLGRNLEQRAKIKATSDMTGLLNVLPSKARLVVTGDSGESSSSVEVPSNSLSVGDQIIVLPGDRVPADGIVTAGRSTVDESSFTGEPLPVTKLTGAEVAAGSINLNGTLTVEVRRPGGETAIGDIVRLVEEAQSREAPVQRLADKVAGHFTYGVMTLSAATFMFWNLFGARLLPPALYHGSAVSLALQLSCTVMVIACPCALGLATPTAVMVGTSLGATKGLLLRGGSVLERFSTVDTIVFDKTGTLTIGRPTVTKVVSQDSTSPYQWSEVDILKFAAGVESNTNHPIGKAIVEAAQSANSPKLKVFDGTFMEEPGSGAVGYIDNKRISVGTLEWVKRHGVLENPFQESDDLKNQSVVYVGVDGVLAGLIYVEDQIREDARHVVESLSKQGISTYLLSGDKKNAAEYVASVVGIPKENVYYGVKPDEKNKFVSRLQKDQKVVAMVGDGINDAAALASAHVGIAIGGGVGAASDVSSIVLMHDRLSQLLDALELSRLTMKTVKQNLWWAFGYNIVGIPVAAGVLLPSTGTMLTPSIAGALMGLSSIGVMTNSLLLKLKFKSRQKEIHGSSVIVDIPSDSDSLDQEKLGHPYPTSRE
The following text describes a protein:
Function:
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of selected small RNAs. Mediates 2'-O-methylation of piRNAs, single-stranded siRNAs and long hairpin RNA genes (hpRNAs). Methylation protects the 3'-end of small RNAs from tailing and trimming and could constitute a recognition signal for appropriate argonaute machineries.
Sequence:
MFSHKFICGSLTKMTETGITFDPPVYEQRYCATIQILEDARWKDQIKKVVEFGCAEMRFFQLMRRIETIEHIGLVDIDKSLLMRNLTSVNPLVSDYIRSRASPLKVQILQGNVADSSEELRDTDAVIAIELIEHVYDDVLAKIPVNIFGFMQPKLVVFSTPNSDFNVIFTRFNPLLPNGFRHEDHKFEWSRDEFKNWCLGIVEKYPNYMFSLTGVGNPPKEYESVGPVSQIAIFVRKDMLEMQLVNPLVSKPNIDKESIPYKLIHTVEYPFYVDTRTEKEKLWTEVQIELQRFKRQFESSEIEEGTYQDTCNMPIAFLLDRLEHVGATKERIEELLLENNLTVENECVLIVSSDQESEWSDPYKFSDRSSQDDALVDQEQEEERWDQGPES
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MKTKMEPYEVEAKSNSSEGFDEVEQVHKGLENSVSQLNCLHRVVLLNKLHNIWVNGNELVTKSDIITTPLRNDLIANSSSDSSVKVELSNTRASSITDNKKVSRCALCGKVFKCLTALKNHESTHDDDDDICSSIEMSVINGINNLVDEDESSSLNLTSPTKEPFEEAHKKNHKSSLVCSICDKEFFQKSKLIQHLSTHSSDQPYACDMCPNRYNKSAALQRHLLSHTGERPFKCDQCHLTYRNKESLKQHYLKHSGSNPYQCEHCDMKTFDRGTLTKHMRKHTGERPYICNCCGHGFKTSDTLKMHLRTHTGEKPYKCEVCSKTFAYKSNMKSHRKRHTGERPYKCTHCSQDFVDPTSYKIHMRRHTGEKPYTCQHCNKLFAHSSGLYAHLKVHSGLRPFKCSKCDKNFVRLAHLKKHVERIHKI
The following text describes a protein:
Function:
May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
Sequence:
MESWGVLHGFCYLWNEITTSFRAGMPLRKHRQHFKKYGSCFTAGEAVDWLYDLLRNNNSFGPKVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDGTNQLFRFLHGLHLSQENSEKIKHEIINEDQENADDNRKLSQEDVEEMWRYVILIYLQAILGVPSLEEVINPKQVIPQYIMYNMANTSKHGVVILQNKSDDLPHWVLSAMKCLANWPRSDDMNNPTYVGFEQDIFSTITDYFLDLLEPLLTFEYYELFVNILVVCGYVIVSYRSSGIHRIQDDPHAFFSVCFIEKKEESDSTERLRISNPGFQERCAKKMQLVNLRNRGVSANDIMGGSCHNLIGLSGMHDLSSNSKLSCCSLEGIVDVSGNSSKEASKGQNTKLFLESKPKQEFLLNLHSEENIQKPFRAGFKRTTTLTAQDQEELCNGKCKSKQLCRSQSLLLRSSTRRNSCINTPLAEMIMKPNVGQSSTSVQTAMQSELGESSAAINKRLCKSSIEFSENSLLPASSVLTGTRSLLQPHLERVAIDGLQLCRLLLPPPNCRKLQLLMRMISQMSQNVDMPKLHDAMGMKSLMIHTFSRCVLCCAEKVDLDKLLAGRLVSFLMDHHQEILQVPTYLQTAVEKHLEYLKKGHIENPGDGLFVPLPTYSYCKQISAQDFEKQKVSTSQAAITELLDNVIKNKSLPLKEKRKNLKQFQKEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFCSLRY
The following text describes a protein:
Function:
Lipolytic acyl hydrolase (LAH); Possesses non-specific lipolytic acyl hydrolase (LAH) activity. Hydrolyzes phospholipids as well as galactolipids. May play a role in disease resistance.
Domain:
The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
Sequence:
MANNKDAELETPLLMPEEEEGGPTAPLLEQGSPELTPRPRLPPPKFGELITVLSIDGGGIHGLIPTVVLKCLEEKLQAIDGEDARIADYFDVIAGMSTGAIIATMLAAPNTNKRTKYTPREIQDFYVNNGPNIFPSKRWWRRPLDLLSASRGPKYDGTFLQKNKIKEVSGEHTLSKLAAPTFDANSLEPLTFSSFQDAKQELVEEAGPELPDVSIGPPSTATPTYFPAHYFDIWVSDMEQSKYHLIDGGNNPTMAAISKITREQLLRNPEFHPSGVDYMKYLVISVGAGCAVHENVPAKRGAFNWFHSRRNSHRPVTDTSSHASAVLADWQVRMLLHNGNRVRKQNYLYIQAPAPLFGEAILPMGNATSKNMADLLNIGYKLLAEKVAMVDLTTGKYETIEDENAPTNDAELQRFSELLVDERNLRLKEHQRQRQGEEQNGVHLLNIIE
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MFRMEIDSSSSELHTPLLSPKDRILKRLSLIDVPEENLEHPSGIITFVRRNHSRLQEIFNAILPTDDEMEAAMKAESDPNIEDLLHESMVWLQWLMFDGDPAEMLQRLALMNAGKRGVCGSVWGHNDIAYRCRTCEHDPTCAICVPCFKNGNHKDHDYSIIYTGGGCCDCGDVTAWKRSGFCSKHKGAEQIQPLQEDIAKTLGPVLDYLLLYWKRKLKIAESNHQNRPTVDDNATEPKKATDVLTSAVVGMLLDFCKCSESLLSFVSGRLCSEVDLLDVVVRAEMFLSTEVVRKLHELLLKLLSDPFFKYEFAKAFLKYYPKVVNEAVKECKDSVFRKYLLLPTFSVQIFTVPTLTPRLVKEMDLLTMLLECLTNIFSSCSREDHRLQVSKWGNLYETTHRVVEDIRFVMSHSTIPKYMTCDRRDLSRTWMKLLAFVQGISPQKRETNIHIEEENENMHLPFVLGHSIANIHALLVAGAFSTEDESVSTTNKQDVDEQDILRHAKVGRLSQESSVSSVTARGTSMDCDSEAVGGNAESIPVLTSISWLMFECLRAIENWLKSDNTANTSGGHLTLLTSRTSNASGFGDRVVDGDYTNELEALSLADWPEIEYDVSSQEISVHIPLHRLLSLVLQRALKRCYGESESSADSSVEFGDFFGHVLGGCHPYGFSAFVMEHPLRIRVFCSEVHAGMWRKNGDAAILSYEWYRSVRWSEQGLELDLFLLQCCAALAPADLYISRIIKRFGLSAYLNLDLERANEYEAALVQEMLNLIIQIVKERRFCGLTTTQCLQRELIYKLSTGNATHSQLVKSLPRDLSKLDQFQQILDTVAEYSYPSGIKQGMYKLRLEYWKELDLYHPRWNSRDLQVAEERYLRFCNVSALTNQLPKWSKVYPPLNGLAKVATCKTILQIIRAVLFYALFTDKLMPSRAPDGVLITALHLLSLALDISQAQIQSGDADNSIPLLAFAGEEISTGVNDGYDNQSLLSLLVSLMRINQKENVYSLVESGGFDLSSLIKNLLQKFAELDPGCLNKLQRLAPEVVNQLPHSTPSGDANNSASMSDSEKRKAKARERQAAIMKKMKAQQSKFMENISSSAESGLNDSNDAEESISEVANDPDGHEQVVCSLCHDASSKSPVSFLVLLQKSRVVSLLDKGPPSLEKEIQRSGKEQVSYSDEDLNTQTSSSSETMISSELMNLFQNTINEFSSTGQPQEVDAFLEFIKIRFPSLKDIHFPQTSHDNSSQPTTSSGDAFEENMYTQILDVMENDVMKDADFSSAECSSNESFLLGKYIASLSNELLNNSSPSVGGSRSKAQPSSVTSCLTYEGFGPSDCNGIYVSSCGHAVHQDCLDRYLRSLKERYTRRIDFEGGHIVDPDQGEFLCPVCRGLANSVLPDLPKEGTKDNGQLKSQILFSSDANDVFLLKQSLSLLQAAADVSSRSEFLKSFPVLHKRGTITNLESVIRLLHEMYFPGDDKLSGSNRLSDSMIMWDTLKYSLTSIEIAARSERTSSATNFSVDALYEELRSSSGFILSLLLKIVHRTRVQSSLDVLLRLMCIKKFAKSICCADTLNEPPSDTYRVEESVMSMLENADMGKRYPDIQFCAMASYPVLASDAFSTLMWILFCLPVPSMTSEKTFFPLVHMCYVVSITQAALTCFGLNESMNDLSHNDSLITDIFKFVGEHRFLSQYFVSNYMDNCRDLTESIRSLSFPFLRRCAVLWKLMNSSASTPFSGALRPSQTFGDRMDYSFGTPEESIEIDELEKMFNIPALDNIVNDEVARSLVKKWLQHIAKEFGVSNPSRVLHLTPVVPFKLMVLPHLYQDLLQRYIKQKCVDCGAVQDEPALCLLCGKLCSPSWKTCCRNNKCQTHAMSCGAGTGVFLLIRKTTILLQRSARQARWPSPYLDAFGEEDIEMHRGKPLYLNEERYAALSHMVASHGLDRSSKVLHQTSIGAFLML
The following text describes a protein:
Function:
Involved in the early step of endocytosis.
Miscellaneous:
MISCELLANEOUS: Present with 1480 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Note=Localizes to the cell periphery and the bud neck. Found at endocytic sites at the cell periphery during the early stages of endocytosis.
Sequence:
MENRNSSTSSRPFSVNNPFRNATVDSSINQYKNDSQFQEWAKNQSRTNSFDMPQLNTRTSSQLSFPNIPEDEPQRNADQQGAFYSGLESFSSGSLSPPSRPLSSKNPFLDDVSSATDFRRSPPPVSRNKNHPTAKEEKEQLRQRYLEESDVSTVGNTRENTDLPPSYEEITSTNGSRRAYPKEKVSRPSSHREHSNSGTYISRRSSSHHHREASSSSTPSKKGKRKSKVIVPKNVDTIDKLDVTGLFGGSFHHDGPFDAVTPHRNKNNKAAPVLAFPVDGPNSTIGGASTKKSALDEVFGRDDTDDSDIYQYSSQTLRRGGDTQDAIKANVGNVQQMDAKNKTELVHGPVTAGLGSSTFLDGAPASSAAIRNDIKAHSYHNRNGGLQRNKSLSQRLGLGGSGDSNAPMTGVRRNLSLSRDNYDVGHSNEGVRRSKTVNSPNRTHKSNYTTDFDGQDDHNEDEEDVYLGVRYNEPNMKKKSTGSKLLSRVKSLKVGRKSQ
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MDGTDGCISEAKVWKVVDSWFYCRGLAAMQIDSYNHFVKHTMKNIMASFPPIQVTRTENFCCYNHILSFSDPQLEPNVHIKPNDCRIQSSSYMAAIKVKISYTIQQYSFSNNEGLVQEVTYEPKLIDFCLFPVMVNSCLCYLNTNKVAGSDIKAHRIINDECPYDEGGYFIIRGAEKAVIAQEGNRPNRLLILPGDPGSKIPYTAQLVSTNSTKNLHSKVVLKYWSTNKWGRTIQDINQPQITFTMQGIRDDLPLFLLILALWQDNVYAARDLLSIVVPDESDTELIEHLLPSYNLFCSTPQSSKDKCIEFLAGRLVVGEQMDSAKAKYDRLMSHLSTRLLPHIGVTPEFHLDKAFFIGYMTNLLLQTVVGRRSPDDRDHWGGKRLQLTGSLLADKFRFEYELFLRRLARKLHDTGSILKVKEDISMVSPNIEGSSFIPQSKYDTHGKVPGLEDPRRLLDRIKVAATSYISKNITSALSTGTWKTNEVVGNTKSGVSQSLVRLSYTSALSQIRRSSSSVEETSKAIGPRLLHTTQFGYMCPAETPEGAKVGLIKNFSLMANVTLDNPKDEHDLRKLLTEYRVQASHGPISVLKSFHTVTNAKKLVSDVKIFLNGSWLGFIDREYVQRLITDLKRWRFEGKINREVSISYLAHKQEISISSDEGRVTRPVFVVITDIHPTLKLVTNLSLAITEEDVETLATIPQMEQWNSLLSGLGTGKCMIEFLDPNEEEMALICMDIYHFKEEIQKAHTIRDIILAHGEDNAINYIKAHNIPLANNYTHLEIHPSMVLSAITSLIPFPDHNQSPRNLYQASMGKQAVGIYALNYLKRFDTSGINVMHYPQLPLVTTRSMPHVKFRYLPAGQNVIIAIAVYSGFNQEDSLIMSQSAVDRGFMRATYYHTYEEMISSAASSINAPDRIEKFCRPIGPNIKGIKDPGCASYLEADGLPRVGNAVNSQRLIIGKIRPNKRSMNSRAVSTYDFQDVSLKVKMEETGRVDSVIIAPDLREQSFLSEGVDSNTTGAEGSLLAKVRVRSSRVPQLGDKFSSRHGQKGTVGMLLRHEDLPFTLDGITPDIIMNPHAIPSRMTIGQLMESVASKLGALSGHEVDGTAFNAPPGSTDKQIAADLHARGYQKHNYEAMMNGMTGEMMTYRIFIGPTFYQRLKHMVLDKISSRNTGPIVTLTRQPNEGRSNYGGMRIGEMEKDAFIAHGATAILRDRLLFSSDVSEFLVCQNCGIICWHADSRKLTTKKSPHCMICSESSTTDSFARITIPYAAKLFFQEIIGMGVFPRIEVETH
The following text describes a protein:
Function:
Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MLYSFLLAIFMFLFIFVYFIKLFLFKFPKKFHFPGSHVLITGGSSGIGRSLAEQAFKLGANVTLLARDVEKLAETQKYLLEHSKTNKKNTVQYFSVDISRNYDEVNDIIKQAESKLGPVDVLINSAGFSVAGSLEDLHVDQFKKLMDLNYLGSVHCTKAVIGQMKARRRGRIVLISSQAGQVGLYGYSAYSGSKFALRGFAESLQMEVLPYNVHVCLAFPPDTKTPGYDEEMKNKPLETKLISESSGLHDSSDVAKKIIQGIVDGTFSIYIGLEGFFMNHLTAGFSPTTNLTDTFIQVFSMGLLRMVSVIYLSTFNKIVRNCAVNKKLL
The following text describes a protein:
Function:
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis.
Subcellular Localization:
Nucleus.
Sequence:
MSRRGRRSEITLPNKRNANGSNESNSLSESRRFSGYGDYFARKKLKLQEQHAARWAETNAEARSQLFSGLRFGINGYTNPPYDELKDMLITHGGTFVQFVENKSSIDYLICTYLTPSKRIAWKNYKVVKPSWVVQSIEQQRILPWTDFRTVGLSSFQTTLQKYLPKAASSTNGAVDETSDERIDREEREEREEQNENVISSTPTTPTSPKPNTNPVPPKEQHITPRSDTSPQYPSVPSTPTVLNDPVVEPPTRLRHIAKHELDGLSDASLYNYRLLQNPNVYKSTAINPQFLSNYFSSSRLHHISMWKMKFRQEVQDLLRSKQKENGHQKRKVSKFSTRYLFHVDFDCFFASVLTRDRPELQGRPVAVAHGTKNSEIASCNYAARDFGVKNGMFVNTARSKCPELELVDYDFDAFESVARTFYQILSHIQHTAIKVVSVDEAVLDMTDIFTNDDEAIKTAESIQTSVLEQTRCTVSVGIGPNLLLARLALRKAKPRGIYLLNEAVAGDYLKTLTVRELPGVGWAQEQKLLLRYKVKTVSDLRSISRESLMKDFGASFGAHLYSIARGHDETLLKEDMIRSSISVDVNWGVRFIFKQDVVDFLGRLCEELVSRMRDCHSRLQQLQLRVLKRAKHASFETLKYLGCGEVDTLTKSAFFNEPTDDTALLTKKCVVLFHACSIDAGEIRGIGLQALKLSDSGTSSKQSLLKLPLLNKRLVKDTPIPSTLQVANTPLPTKTVSKLVTPIKKGPPDSPFRIPSTPIELPSPSQLDLEVLKELPTPLRDEIQRQAQAQKRSIYDIPTQLDSGFLQNIPTPIRNEVLEEHKRLHPPVLQLKSHKTPPAAKNVKQPLGATSNAFELMRRPAKRKQPLYEEVDPSVFQELPTPIRKEIKRDRNMQFRLPKTDTVAVPQHPVLSFQGAQTMTELRRLVCHWYKHCIRGPHQQDVDYFIKYVCKLITVEKNLAKAHMILHWFRHIVQPSQRWSKALEKVILAVQTECLARGVPPLMDS
The following text describes a protein:
Function:
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MGFGGMFKELAVVAVVVTIMATSVAAQAKPGCQSKCGNISIPYPFGTSNGCYISRDFFINCDTSFNPPKAFLSDTGLELQVLNIFPDDGSLRIQNHRSVGYDCYNSSGPTSSDTSVFLHRKFSISYSRNKFTAIGCDTIAYINGFSRPDSSNLVFKAKNFSTGCLTFCGDVGDVINGSCSGIGCCQTAIPRGMQAYLFNFTSLQSHSTVLRFNPCSYGFLVEDGVYTFSTSDLSNIDFNKRKYPLILDWTIGNQTCEEAKMDPKNYACKQNSACIDPESGPGYLCKCNDGFQGNPYLSNGCQDINECEALKPCNEFGICHNTLGSYYCSCPEGFEGDGRKYGTGCSPEPKAHRESFPILLVALGWYT
The following text describes a protein:
Function:
Represses puuA, puuD and puuP.
Sequence:
MSDEGLAPGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYGLSLSEFFSEPEKPDEPQVVINQDDLIEMGSQGVSMKLVHNGNPNRTLAMIFETYQPGTTTGERIKHQGEEIGTVLEGEIVLTINGQDYHLVAGQSYAINTGIPHSFSNTSAGICRIISAHTPTTF
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Sequence:
MSHMAYTPKKQVRTRNTHAAFPTLPIDEIVQCLPGLDCMVTEEELLRPTSKFVQSMYAQIATSLLGINRESMAPALAACAAGTEHPETQEDARMLFALQKPLYDLFVASGVTDYNISDILKPSPERLRVQLSAIINYARFREIREKWYEKMSEELNEEEEARTMRLKNQEEKLRRKVELIALIGDTPDQDLVEQHRINDSRKSELKRLHDQNLQLNDERERNKAELRVVVNRLRHKHQLMESLQEEVARLNSYVVDNPKNLQEEVVELSKRVKERETVRRMLGERVQKLDLSVDSFKDFQVDVSSCLSAFQKLSDEQEAHSKAVRKITTQKELLEHVGINSRQAEGRRDVLQQEIEAAESKIARIQQDMSESDRQTSRRMEELRRQIGTLDAERALVVQQNNTAQKRLAELENDMATERDRYEAQLKMAREEAEKLQTQFREYFVEVGRRLN
The following text describes a protein:
Function:
Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
Subcellular Localization:
Secreted.
Sequence:
MDVRCRFVFTVCALLLMIARTGGSPFTDCVQSKGKAGFYEGSIDSTESGVKCMNWSDVPGVRERYQGKGLGDHTFCRNPDGRIRPWCFFTNNRGRIDWGYCDCKQGSLRLQGGRSKLDGTVEVYLNGVWGTICSNGWDDQDAAVVCRQLGQGYRAHARMSPLSRLVVSVVHWQTVGCEGQEDDLLQCNRTVWNGGECENRQAAAVSCMPVETSVFVPVRLSGGPSAYEGRVEVYHAGQWGTVCDDQWDDNDAEVVCRQLGLGGIAKAWVGAYFGAGSGRVFLDEVSCTGNELSIEQCPKTAWGEHNCDHTEDAGVSCVPLTDGAVRLVGGVKGYEGRLEVHYRGQWGTVCDDGWTQTNTQVVCRQLGFRSGESVSAGRFGIAAGPVLLDDVRCTGKEPTVTHCSRRGWFKHDCTHRQDVAIVCSPQCSRHGVPNSLPVRLVGGENEREGRVEILVGGQWGTVCDDGWTDRDAEVVCRQLGYSGLAKARVMAYFGEGEGPIHIDNVKCTGGEHSLTDCIKQPFGTHNCRHSEDAGVICNYGLQQDSPGVKEAVGSMCGLRLSHTRQKRIIGGENSLRGGWPWQAAVRLRGSQADGRLVCGATLISSCWILTSAHCFKRYGNSTGLYKVRVGDYHSLVPEEYEEEYAVEKIVLHPRYHADSSDYDLALLRVSGHRAHRGVTGQCVTLSRSVLPACLPVRREKVPKGIANCYITGWGDTGRAYSKTLQQASISVLSKRQCEQRYSEQFTNRMLCAGSSHDAQRVDSCRGDSGGPLVCERPSGSWVVYGVTSWGHACRLQEAPGVYTKVSAFVPWIKKVIGQ
The following text describes a protein:
Function:
Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.
Subcellular Localization:
Nucleus.
Sequence:
KAGLDVASYGTGQHVKLLGPSIREPNVYDFGTPYKQMFDNLCRKDVKLYSRNGILPMLKRNLGVKLAPQRWQDNAADGPFDVVITFEEKHFDLVLEDLHIETVFS
The following text describes a protein:
Function:
Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-301 reduces this inhibitory activity.
Subcellular Localization:
Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line. Nucleus. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm. Phosphorylation at Ser-301 promotes translocation to the nucleus.
Sequence:
MEQTEGNSSEDGTTVSPTAGNLETPGSQGIAEEVAEGTVGTSDKEGPSDWAEHLCKAASKSGESGGSPGEASILDELKTDLQGEARGKDEAQGDLAEEKVGKEDTTAASQEDTGKKEETKPEPNEVREKEEAMLASEKQKVDEKETNLESKEKSDVNDKAKPEPKEDAGAEVTVNEAETESQEEADVKDQAKPELPEVDGKETGSDTKELVEPESPTEEQEQGKENESEERAAVIPSSPEEWPESPTDEGPSLSPDGLAPESTGETSPSASESSPSEVPGSPTEPQPSEKKKDRAPERRVSAPSRPRGPRAQNRKAIMDKFGGAASGPTALFRNTKAAGAAIGGVKNMLLEWCRAMTRNYEHVDIQNFSSSWSSGMAFCALIHKFFPEAFDYAELDPAKRRHNFTLAFSTAEKLADCAQLLEVDDMVRLAVPDSKCVYTYIQELYRSLVQKGLVKTKKK
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MEQETSMRAIIRNWKHGYRALLHMRWAADFGFHISVVGLVGVVGFVLAIIRDGKLGEKRKKHLEKLCLVPGLQNLGNNCFLNVILQALASCSYFQSFLQKILDECESTLVDRQGESLPLTITLSDLLEELGMAGERRVALSPHKVMSALSLYIQNFDLTSQQDAAEAFLHLLSSLREEFSDIYLPNQSTLADIFASQTSRILTPERKEVQNEQKRWQQHYLGPFDGIIGSILSCRSCSYQISLDFQFFHSLPLFPVLYGASTIMAGCTLEDCLWQFVLAEKLENYYCSHCWHSAAIKFLSCKGANEIEIEKLKRCSAEESCDCRSFCCLENLPWSNNFSNTLKQLCIARCPKILCLHLQRASINEVGELIKLQGHIAFPLILDLSPFMTTKVEITNWEGVHKGQLKLQNQKTRPHLNLINAQYESILNRISKPTGEKVSSEILVANGSQCTTSPGESLPEKSKLYPTDGCSKASNIDMHEQHNDKVSLTSKLPPSETKLYRLASVVEHFGRPGGGHYTVYRSMRTKSDEEDSDEYSEPATTKWFCISDSQVCSVSEKDVLAAEASLLFYERIV
The following text describes a protein:
Function:
Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor.
Subcellular Localization:
Secreted.
Sequence:
MQNLSLSLVILSVLIAVTLACKCREQSTKESFCNAHWVSHVKVKVRVGKQGLPEGSERKGLNNLRYTVQHVEVFKKPSNMTTLPDEIFTPSEAPACGLKIAAGHEYLLAGRVEGPNALYTVLCGQVLPDDRSQTSFENVLEWKNVPQTLQSQVKSIKC