lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Zinc-finger transcriptional repressor. In larval brain, involved in the maintenance of cell fate of intermediate neural progenitors (INPs) that derive from type II neuroblasts. Restricts INP developmental potential and dedifferentiation by interacting with HDAC3 and the chromatin remodeling Brahma-associated protein (BAP) complex. Restricts INP proliferation by regulating neuroblast specific factors such as prospero, pnt and grh, and by antagonizing the function of self-renewal factors, such as klu, dpn and E(spl)mgamma-HLH. In the optic lobe, essential for coordinating the innervation/ targeting of the L3 and R8 axons to the M3 layer of the medulla. Early in medulla development, functions in parallel to CadN and Sema1a pathways to promote targeting of the L3 growth cones to the proximal domain of the outer medulla possibly by controlling the expression of various cell surface genes such as dpr1 and dpr17 which function in L3 growth cone targeting. Then once L3 growth cones segregate into the developing M3 layer, it activates the expression of netrins NetA and NetB which act locally to promote the attachment of R8 growth cones within the M3 layer.
Subcellular Localization:
Nucleus.
Domain:
The second, third and fourth zinc finger domains are necessary for repressing gene transcription.
Sequence:
MVYFSPRGMQPCSPAGEIAMMPPSKSPVMESAASEQNPAQQSQQQDEQSAKRACPLKFSIAKIMEPDHRPSQVPPPQPAPVSFATNDDDEDEDPEIDADSERSCSPIEVISLDQSPSTVNYDSAFKKYVPGPCSGATSSVASPPSTAAVQQFVSSRHQELLSQYPLLYYAPNQLMCAAAAAQYAALTAQQQSLASAAHLSSFTASLNASLHHSQSLRRNLGHPLAAAAAVAAVAQSQAVPNLQHTLEKSPVAQRTAQSSGLQANLKRKRSPQDQGEVTPPPASTATSATGARSRSPSPQGSIEDSSPGSASGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHSRIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQVYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMRKLHEIGGDLDDLDMPPTYDRRREYTRREPLASGYGQASGQLTPDSSSGSMSPPINVTTPPLSSGETSNPAWPRSAVSQYPPGGFHHQLGVAPPHDYPSGSAFLQLQPQQPHPQSQQHHQQQQRLSETFIAKVF
The following text describes a protein:
Function:
This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
Sequence:
MKSTRKSATQRRHRRLRRHLSGTSERPRLAVFRSNDHIYAQVIDDVAQHTLAAASTLDPDLKKSLSSTATQEASAEVGKLVAQRAIAKGINQVVFDRGGKLYHGRVKALAEAAREAGLNF
The following text describes a protein:
Function:
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1 (By similarity). Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MTSETVIAPSLSTAQNDGTFTYDKVKSTAKERKHLNLKNPSDANEIKSKIWNYYSLSELIQYLGQKENDDFKYKRITLQFPDNLICDSATIVHELQRELNIVPQANQDTGESNTAQRVWILADTSYSACCVDEVAAEHVRSDLVVHFGDACLNEIDKLQAVFVLGKPTLDVDAIVKQIKTAYSTEQKVVLMSDAPHTYLLPEIAKQLPDYDILIADLPKTSRAKIIGYTPPPTGHKKFNRVFNTDTVEFGKYELFHITSPESPRLLQLTTNFASVTTYDPISGTVSTGPFPNLMRRYKYVHQARMAGTVGILVNTLSLANTKVLLNTIKEKIKEAGKKHYIFVVGKPNVAKLANFESVDIWCILGCDHQGIIIDQINEYYKPIVTPYELLLGLSDELSWTGKWVVDYKSVLEEYGNEVIQQNEDPDTDEDLPPVFDPVTGRYVSTSKPLRQINHLMVTSSEQGGVDDHDNQLVKRFSNAVAIKGTVSTSAIHLQNRHWTGLGSDYTEDENATGALVEDGRKGIARGYDI
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
LQGFAAPSSDKLLPDLIPQEQHVYTIVLDLNETLVFSEWKRERGWGTFKRPGVEAFLEKLAHYYEIVVYSDQLSFYVDPILERLDQKGCIRYRLARDATNYLDGKHFRDLSKLNRDPKKIMYISGHALDTCLQPENAVPIKPWKLESDDTALLDLLPFLEFVARQRPPDVRTVLESYKGRDIATEFRERAKQNQRFESWISI
The following text describes a protein:
Function:
Probable structural component of the cell wall involved in cell wall integrity and virulence.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MIHYLIFPILLIFFQIIKSSGYYVPANGDDWTILKPPSCKNKLPGQYIDSLPFTFGIVVNPYILNEDGDYEKPIVSKIKPSLTTTTFVTSIITTSTATAPGSKPTKTKDIIVQIHDGQVQKMKHKHDYSSGGGDDDDDDEDCFDEKNIDMAAKRDYQDMNTQEQANEDSGQVLAESDSHQQVVDQNQQINEEEEETQEQQMQEENNNTNEIEDNKVQEFETIEEIYDDIDNNESRPNNSKKYHKKRPHNNYENKHGHKDYHEDHHHNHRYKDHENGHEEDDHKWNKPKPMPEQEEQEQEQEQKPKHEKSEGYESEFVSPVYSVACYTNSTLKMTLTDGILRDSDDRIGCIVSGHQFQFDGPTPQHGAIYAAGWSVTKQGQLALGDSTKFYQCASGDFYNLYDEPIAFQCHPVTLDVVELIEC
The following text describes a protein:
Function:
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (By similarity). Required for nucleus structure organization (e.g. size and shape). Involved in the maintenance of interphase chromocenter integrity and organization.
Subcellular Localization:
Nucleus membrane; Peripheral membrane protein. Nucleus, nucleoplasm. Nucleus lamina. Cytoplasm. Note=Recruited to the nucleus envelope (NE) by SUN proteins and is immobilised therein (By similarity). Localized frequently to the nuclear periphery as punctate structures of different sizes. During prometaphase to anaphase, localized diffusely in the cytoplasm. Later assembled into punctate structures in the cytoplasm and then to the chromatin surface. Relocalized in part to the nuclear periphery during late telophase, the other part is still localized on the punctate structures.
Sequence:
MATSSRSERFPITPSTAATNRLTITPNSRVLKSPLTEEIMWKRLKDAGFDEQSIKNRDKAALIAYIAKLESEVYDYQHNMGLLLLEKNELSSQYEEIKASVDESDLTHMREKSAYVSALAEAKKREESLKKDVGIAKECISSLEKTLHEMRAECAETKVSAGSTMSEAHVMIEDALKKLADAEAKMRAAEALQAEANRYHRIAERKLKEVESREDDLTRRLASFKSECETKENEMVIERQTLNERRKSLQQEHERLLDAQVSLNQREDHIFARSQELAELEKGLDTAKTTFEEERKAFEDKKSNLEIALALCAKREEAVSERESSLLKKEQELLVAEEKIASKESELIQNVLANQEVILRKRKSDVEAELECKSKSVEVEIESKRRAWELREVDIKQREDLVGEKEHDLEVQSRALAEKEKDITEKSFNLDEKEKNLVATEEDINRKTTMLEDEKERLRKLDLELQQSLTSLEDKRKRVDSATQKLEALKSETSELSTLEMKLKEELDDLRAQKLEMLAEADRLKVEKAKFEAEWEHIDVKREELRKEAEYITRQREAFSMYLKDERDNIKEERDALRNQHKNDVESLNREREEFMNKMVEEHSEWLSKIQRERADFLLGIEMQKRELEYCIENKREELENSSRDREKAFEQEKKLEEERIQSLKEMAEKELEHVQVELKRLDAERLEIKLDRERREREWAELKDSVEELKVQREKLETQRHMLRAERDEIRHEIEELKKLENLKVALDDMSMAKMQLSNLERSWEKVSALKQKVVSRDDELDLQNGVSTVSNSEDGYNSSMERQNGLTPSSATPFSWIKRCTNLIFKTSPEKSTLMHHYEEEGGVPSEKLKLESSRREEKAYTEGLSIAVERLEAGRKRRGNTSGDETSEPSNNKKRKHDVTQKYSDEADTQSVISSPQNVPEDKHELPSSQTQTPSGMVVISETVKITRVTCETEVTNKVTTLDCSESPSEAGRKMGEETEDGDCNQTGINASETVIHNEAATEDICT
The following text describes a protein:
Function:
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.
Subcellular Localization:
Secreted.
Sequence:
SRLCVRSGAVLLVVLTCTVPSAVLVSRDEAHGVLRRRPRANAGWLEELKMGNLERECMEEKCSYEEAREVYEHDEATNEFWTNYNVEKRCESNPCQNNGTCVNSQDAYTCFCPEGFNGRNCEEAIEDTLKCLYLNGGCEHFCNDTGGQRSCECAQGYALGEDGETCEPQDLYPCGKIPILKEDQSAKTDKSSDSRGRIVGGTECPKGHCPWQVLLEYNKKPFCGGVILTPYWVITASHCLEKLKAAYLKVVAGKGEHNIDKKEGTEQTIQVAKVIMHKKYRVQNTDNDIALLKLQEPIVYSAYAVPICLPQKELSERDLAAIRFSTVSGWGQMSENGPISPVLQMLEVPRQRSQDCREQSKINITDNMFCAGYFDGKQDSCKGDSGGPLVTRYKNTWFLTGIVSWGKGCARPGYYGIYTRVSNYLDWIQQNTATQSLKGNAT
The following text describes a protein:
Function:
FliG is one of 2 proteins (FliG, FliN) that might form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Bacterial flagellum basal body.
Sequence:
MAQEKSALSKAQKAAVLLLSLPEEVSMNIVKELSEEELQKLFALAKDLESVPEEEIENIAEELLDEIKKAGIKIKKPEEFIENIKKVIPPTLAEKFRGILELGDAEKILKEIEKVDSRILASLLKNEHPQTIALFLSQLSPKKSAEIIQNLPEELKKEVVKRIATLENVNVQYVKELAQILLEEISSLGAKEALKLEGTAVAAELLNTLDKETRELILQSIGQEDPLLEERIREKMFTFEDIRKLSDRDIIEILKVVDKNTLMIALLGAPEDIKQKFLSNMSKRAAKLFLEDMEALGPVKKSEIEKAQRQVVNIIRKMIDEGKIEIGD
The following text describes a protein:
Function:
Chromatin reader component of the transcription coactivator SAGA complex. SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription. At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B. SAGA interacts with DNA via upstream activating sequences (UASs) (By similarity). Sgf29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). Required to facilitate crosstalk between gcn5 acetyltransferase activity and H3K4me3 recognition.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The SGF29 C-terminal (also named tudor-like) domain mediates binding to methylated 'Lys-4' of histone H3 (H3K4me).
Sequence:
MVRPINAEEDVTSMWVKFHESLNPIRSSLIKQEECYKTVDGDDNPIEERIKACDAGIQTSEEQKKELEHTMQSLEMIINVLEKANEKPVITNSPLTRSRRNRGTSFTANTVTFTPGMSVAFKLPYTRHNEGGDWIQCIIIKVTGEGAKQRFEVQDPEPDDDGNAGQIYKTTANHLIQIPAKGTPLPPISPKTNVLARYPETTTFYRAEVIRTLPDGSCKLRFEGEEEVGKETVVERHLVLEYNG
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MPRAFLIKHKRARVDNIADELLARHEMGHGDGEDIRMRGSERGLSPSRFGQHICTKGLSKRELNAVEMDMEARGLMNFHPAYTLAPGMYPPPPPLLRMSTGSAFEKVHPGAPMPENLGVGFGPLAGSVDPQRLVLNPWLAGYPELAGHNILRDRLLNHPASAYLIADPKRGLYQMPHGAFLSKPLDEPLDLKVRGPSREGHEDEKRELTRMSKDYHPEDVLSFKKRSLGGPVRLPVGTEPDDYPRYPPMSSAIHPSSYPFFGIPYGHLLAQKYPGGFGLRPVERNQYLGQRGPKRMEMSPPMASHASPQPDLDQPPICSVKPIFNEQDESSNSPSPLSNAYLSPTILNQPRYALSQESIDDDDSDNQSPSPVGGKRLTRQPILGVEYIQNGIDNELRHDLDSSQEAEQQHLSQDPEEQYLLQDEPNPIPETDAKTGCQPNVDEKINLPMIPKFKGETKGRRSNSAKTPQPRKYMCDVCGKGFSRSNTLVTHKRIHTGDKPFSCELCGRAFRQPGNLTRHRLTHTTVKPYVCSQCGKAFNRASNLHTHMRTHTNYKPFVCQYCGKGFHQKIDMKIHSYTHTGEKPHKCKKCGRGFKQLTHLTYHMRTHSEVKMYTCAYCGKGFNQKGNLQAHIYRHTGERPYRCEVCDKGFTLASTLNTHRRTHAEKKPFACQYCGKDFYQRNALKSHLLASHPYSGGESLL
The following text describes a protein:
Function:
May play a role in cell differentiation in the intestinal epithelium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFSASTPGYSSLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFLRTLIAAILYLITSIVVLVERGNHSKIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
The following text describes a protein:
Function:
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs); Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MTAYRSPLMDPDTKPIGNMALLPIRSQFKGPAPRETKDTDIVDGAIYYFKANAFFKNYDIKNECNSKSQGEKEMYTLGITNFPIPGKPGFPLNAIYAKPANKQEDETGLRLCEKVFDPQNDKPSKGWTCFVKRQFMNKSLSGLGQ
The following text describes a protein:
Function:
Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
Subcellular Localization:
Cytoplasm.
Sequence:
MSVDTYTETTKIDKLLKKPTSHFQLSTTQLYNKILDNNEGVLTELGAVNASTGKYTGRSPKDKFFVSEPSYRDNIDWGEINQPIDEETFLKLYHKVLDYLDKKDELYVFKGYAGSDKDTMLKLTVINELAWHNLFAKNMFIRPESKEEATKIKPNFTIVSAPHFKADPEVDGTKSETFVIISFKHKVILIGGTEYAGEMKKGIFSVMNYLLPMQDIMSMHCSANVGEKGDVALFFGLSGTGKTTLSADPHRKLIGDDEHGWNKNGVFNIEGGCYAKAINLSKEKEPQIFDAIKYGAILENTVVAEDGSVDFEDNRYTENTRAAYPINHIDNIVVPSKAAHPNTIIFLTADAFGVIPPISKLNKDQAMYHFLSGFTSKLAGTERGVTEPEPSFSTCFGAPFFPLHPTVYADLLGELIDLHDVDVYLVNTGWTGGKYGVGRRISLHYTRQMVNQAISGKLKNAEYTKDSTFGLSIPVEIEDVPKTILNPINAWSDKEKYKAQAEDLIQRFEKNFEKFGEKVEHIAEKGSFNK
The following text describes a protein:
Function:
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex, causes transcriptional pausing.
Subcellular Localization:
Nucleus. Chromosome. Note=Associates with polytene chromosomes. Associates with the hsp70 promoter when it is inactive, but not when it is activated. The NELF complex possibly dissociates from chromatin following phosphorylation of RNA polymerase II.
Sequence:
MVYIHFPNNLTEEEQMLQAKYQKLKKKKKALQAHKAPKPEPESSLTLKRPTDARDAREVARKLIKSGAIPAIQKQTKQDQTSFKRPKGQERAKRSTSETTVASYQPFSSTQNDVAQETIISEIIKEEPRRQNLYQHFATERDREERGMPEKVPMDTAQPEKPRAGNTIFVSGNKVTEDFLKKTFNDYGTIVNVSMEIEKSRGFVSFAKPESADRAIAEIHGKNVNGINLQVQLARRQPQIEPINDASSSAVWSSIAASKSQKGSHKDHREMVQYDEDFLL
The following text describes a protein:
Function:
May inhibit the adenylyl cyclase-stimulating activity of guanine nucleotide-binding protein G(s) subunit alpha which is produced from the same locus in a different open reading frame.
Miscellaneous:
MISCELLANEOUS: This protein is produced by a bicistronic gene which also produces the guanine nucleotide-binding protein G(s) subunit alpha from an overlapping reading frame.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cell projection, ruffle. Note=Predominantly associated with cell membrane ruffles.
Sequence:
MSPSPTRLTVRSVDPLKTPNLTSRAPVRPSRKSKWAETTAHLQRKPCHSRSNSPAWEISGPPWSSLDHLDPIRHQSLQPSDFGARTPTGAHPGLGAYSPPPEEAMPFEFNEPAQEDRCQPPLQVPDLAPGGPEAWVSRALPAEPGNLGFENTGFREDYSPPPEESVPFQLDGEEFGGDSPPPDSASHATNRHWRFEFPTVAVPSTLCLRPARTRLPSGSRAPLADHARLSDLLTSHTTFPQWRSPDPCLRLAEPPLGSTTTPLSIWTAPQSQVMARPSKSREPQLRASTQRDPHLSDKQPRQETALSAAPLQRRQKSPPSSEEKDPPPNLKQCISSQLLLRSPERTLPKPIRTQLHTQFFRSVLRKSEESQPCPPIFRLLLKMRAQMSGQNQTEGQPQPPLPSPKTTENQPPPPPPSQPPSQPLSQPPSQPPSQPPSQLPRQSLTPKPSLPPGQSPTPKRSPQPRQPLPRRRSLPPGQPPSPLRSPLPGLSLLPEPIQPPGLSLEPQRCQPLLGQPPLEQPMQVLWSGEPGHSRLLQPLGHPSLPAQQLPPEQPLLPAQSLPAGQPLPPQAGPILDPPARRSRLLTRLLRGLLRGRVPGLTNTNVAEAAAGMRLRPASARSSPPAMSRKKGPLAASSGFCGETAALASPGATQSGATRSATSSPEPSEAASVYLSVPDHDPSAPGRPRILWKRGANRCAKKPWRCESRSAQIRNAASSSTSNWRRRRWTTCVHTACCF
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MNWDDLRIIAAVRDEGTYAGASARLRIDETTVGRRLSRIERALGLRLFEAADGVRRPTRSCEAVLAHVEAMAAHAAEIGRVGESLAGPVGRLRIASTNTVAEEVLSPRASDFLRANPGLTLQFLTSSENVKFSRWEADLAIRLRKPDKGDFAISRLGDIKLYYFEPVTTEGEPMLCAYPDELGAIPEMQFLRMKQARARCVTDNVRVIRNLIRAHQAAGVLPEHVCADLLGDRRLRATLLPKRRDVWLLVQNHLKRDAATRVTIDWVRACFQETSRS
The following text describes a protein:
Function:
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular Localization:
Nucleus.
Sequence:
MEASRPAHARHMESNAARAAAAAAGEGVGDHDDDGEEEEEEEKWREALAAAWGQSRAKREAIRACYAAVKDMIRAEKDGADMRRLGVAMGEIKQLHHKVQRPKEQVADGEALLELVNSLAITAKSKKKDGPTPSEFVTSLLTKFGVRASLLDASIESFSCSDLGAMASPLFMTATGCQTMNGALNLAIEERRKRVARRLFDRFPSKPAGLYETTPDLDERNDTDKNMAVMFKLLRKNKCVKLENLILNRQSFAQTVENIFALSFLVKDGRVEIDVDDKGNHFVVPRNAPAAELITSREVINSQYVFRFDTKDWKIMEGVVEPGDELMPHRQNNIGEHYNNAKSYSASEPQRKRDEFAQGEGMDETLIKPCAEDVILKRKRRSEAESLKHWFSSCKWQ
The following text describes a protein:
Function:
Participates in the second step of pre-mRNA splicing (By similarity). Down-regulates the expression of potassium channel subunits.
Subcellular Localization:
Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs.
Sequence:
MDILKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKVQPKEDDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPMRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNSREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLMTICQKHFPTDPSKCVEYNAL
The following text describes a protein:
Function:
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MYNRHIAHLSAVQANDTRHNATLRFQSRPTDNVYSDPRLEQLIVYRALLQHLLQQKDHYDHERELELQRLERFRSEGANERRLQIQEQVLKKAQGMLPGIVFKMRNEVDKLKRFLDIDKQQELRQLDTALYDNCVELLNNCQSSLENIN
The following text describes a protein:
Function:
Golgi-localized UDP-N-acetylglucosamine (UDP-GlcNAc) transporter that transports UDP-N-acetylglucosamine into Golgi lumen. Contributes to lysosomal targeting of NPC2, a key protein required for lysosomal cholesterol exiting, and that utilizes the mannose-6-phosphate (M6P) modification pathway for its lysosomal targeting.
Subcellular Localization:
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Sequence:
MNVRRSLLGLTFCTCYLASHLTNKYVLSVLKFTYPTLFQGWQTFIGGLLLHMSWKLGWVELHSSPRSDVLIWLPASALFVGIIYAGSKALSRLAVPVFFILHNVAEVLTCGYQKCVWKEKTSLSKICSALFLLAAAGCLPFQDSQFDPDGYFWALIHIFCVGSYKILRKSRKPTVLSDIDQQYLNYIFSMVLLAFASHPTGDLFGALDFPFLYFYRFHGSCCASGVLGFFLMLSTVRLRSILAPGQCAAWILCAKVVTAGLSMLLFDMALTKATVGCFLLGGLGEALLVFSERRSSS
The following text describes a protein:
Function:
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MKSVCIALLASSVSAFAPSQQGPVKSALSYASELDSMTGTGIESPKVFDPLNLSDYVPVDWARRAELSNGRSAMLATVGWFFPKVFGTFDSTDVTTTDPIDAIMQADPQWWAQWILICGVFETWKYKKEMEGKSFLGGADPAVDYLKLWPADAAAQEEMKTKELKNARLAMIGIAGFAANHFIPGSCPVPDFIA
The following text describes a protein:
Function:
Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. Acts on position 39 in mitochondrial tRNA(Phe). Also catalyzes pseudouridylation of mRNAs in nucleus: acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing.
Subcellular Localization:
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Mainly localizes to mitochondrion. Localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly. Also found in nucleus and cytoplasm.
Sequence:
MAAPRWSASGPWIRGNGQGCGSLFTLVSKPFCAAAAASTAINAQRLAEKLRAQKREQDTKKEPVSTNAVQRRVQEIVRFTRQLQRVHPNVLAKALTRGILHQDKNLVVINKPYGLPVHGGPGVQLCITDVLPILAKMLHGHKAEPLHLCHRLDKETTGVMVLAWDKDMAHQVQELFRTRQVVKKYWAITVHVPMPSAGVVDIPIVEKEAQGQQQHHKMTLSPSYRMDDGKMVKVRRSRNAQVAVTQYQVLSSTLSSALVELQPITGIKHQLRVHLSFGLDCPILGDHKYSDWNRLAPQKLSVGTLKKLGLEQSKARYIPLHLHARQLILPALGSGKEELNLVCKLPRFFVHSLHRLRLEMPNEDQNENNEAKCLGAQ
The following text describes a protein:
Function:
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates YPT6 by exchanging bound GDP for free GTP. It is thereby required for efficient fusion of endosome-derived vesicles with the Golgi. The RIC1-RGP1 participates in the recycling of SNC1, presumably by mediating fusion of endosomal vesicles with the Golgi compartment; Required for proper mitotic growth.
Miscellaneous:
MISCELLANEOUS: Present with 589 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus.
Sequence:
MRAHRIDTFLIRENIKLEIIHESNSYFGGEHISIAFRFKHLGSQHELFNYKEKLLTVDKAVEEKLEQQAKVQDDGEGTMENQTWSLKSLLGAFKRTGEPEESVDVDNMKMLNESKMLREKIQKQMYFHQPVTLISGYVQISGVFQYDSEVISESKFKQDEVKMVGLDIVPGHTTNSVLALEDGEHFKGKRNLTNYLNSDYTNVTNGLLFSESGSRGRTGTYNERTLMISNDTSIKTLPLLLIPQTLLFSEISLEPGEVRTFYFKSTKLPKDICPSYSSSKVASINYTLEVGADVLSDDNIEKFSNRVPITIAPYISSNAEQYTSRLDKPAIILKTGNIKELKPRLFTRKVSTASAVSFGRRKSSIIDIDSPLEDNEFVKRVKKNFIELVESNQNVSRDIDELIDLQMGVQFGKDEDSSDPEPNDSHFSNEMVTSAESSLRSDAVTKRRKSYSVRDNISNLEQKMWNDCSLVKSDENSNLLPQLINLQNAYQINRNNETMAKVSLSAPFYKTTDDINLVIELDPITTPLLKVTSLTVSLESFEIINPKYKTEGKGIGSKPKGNSVYEKHFICFDECKSVSVKLLPPRSPTNQITGQFKTDVFQHKWMIGLKFVIIAKTESITLDQFYEDKKGILFHSKENLEGEEFTCYVPIPILCTSEDFMGW
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MGCSCSSVRERDVGYPPKLVAVHYPGMTQSPVNIDTVDPLVMYCDAYLLSHPLTLQNYRPGCARRMVNDGNTFKIEMRQEKQESVASLPGHITGDSEANVPKISGGPLHDEFKLLQIHAHWGATDQDGSEHTVDGDVFQGEVHLVHMNTKYPSFEQALTKRDGLAVLGVFLQLTDEGHEGHESFKTITDKLDSISYKGDSVDLDDNFNPQCLIPDDHQKYWSYPGSLTTGGYQECVIWIIFKNTLKVSHQQLEALRSLRSYPRGKDPKIVRDPITERRLSAHILDNYRTTQPLHKRRIRASFPGNYSMYTFQKN