lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in organellar RNA editing. Required for the processing of multiple editing sites in plastids.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MASFTTTSSSSLLLKTLLPVSHLNRFSTLSGIRVGDSWTPLLRNISTAGSRRRVAIVKAATVDSDYSSKRSNSNEQRETIMLPGCDYNHWLIVMEFPKDPAPSRDQMIDTYLNTLATVLGSMEEAKKNMYAFSTTTYTGFQCTIDEETSEKFKGLPGVLWVLPDSYIDVKNKDYGGDKYINGEIIPCTYPTYQPKQRNNTKYQSKRYERKRDGPPPPEQRKPRQEPAASDSS
The following text describes a protein:
Function:
Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endomembrane system; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MDITQSFKASVMTVRLQRKAELAGKAKPATVPTKTGPIGPKDDFAKQAKEVCNKITSLRNVLIENRTAYMRIGQHLKSAAHMTDAQRDLIDRESEKFVTFYTQHLAKMRSDWKSAKRKPQERQHIDAVLDLLVSYLHSVEQIYLDQKKYRVQHELETYRLLKLAADKKKIPVRPAGSNSGKLGRRQVSNDDSEATKSSSQANGNHDESADNDWNNDAWGDWDEDEEGDEVDDHDGEKGKEANQANQHKPRTRKRSKANRSDLNNSSSKMALDEELQQQQEADDDDPLSAEDVQLFEAENVHIYNFLQGVSEEVEQIEKNVVDIAQLQDIFTEKVAMQQHNIDRIVSAVVGTTENVKDANEQIRQATQRNAGLRVWSLFFLLVMSFSLLFLDWYYD
The following text describes a protein:
Function:
Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target genes and can act as a transcriptional activator and repressor regulating target genes by binding to an interferon-stimulated response element (ISRE) in their promoters. Has an essentail role in IFNG-dependent immunity to mycobacteria. Competes with the transcriptional repressor ZBED2 for binding to a common consensus sequence in gene promoters. Its target genes for transcriptional activation activity include: genes involved in anti-viral response, such as IFN-alpha/beta, RIGI, TNFSF10/TRAIL, ZBP1, OAS1/2, PIAS1/GBP, EIF2AK2/PKR and RSAD2/viperin; antibacterial response, such as GBP2, GBP5 and NOS2/INOS; anti-proliferative response, such as p53/TP53, LOX and CDKN1A; apoptosis, such as BBC3/PUMA, CASP1, CASP7 and CASP8; immune response, such as IL7, IL12A/B and IL15, PTGS2/COX2 and CYBB; DNA damage responses and DNA repair, such as POLQ/POLH; MHC class I expression, such as TAP1, PSMB9/LMP2, PSME1/PA28A, PSME2/PA28B and B2M and MHC class II expression, such as CIITA; metabolic enzymes, such as ACOD1/IRG1. Represses genes involved in anti-proliferative response, such as BIRC5/survivin, CCNB1, CCNE1, CDK1, CDK2 and CDK4 and in immune response, such as FOXP3, IL4, ANXA2 and TLR4. Stimulates p53/TP53-dependent transcription through enhanced recruitment of EP300 leading to increased acetylation of p53/TP53. Plays an important role in immune response directly affecting NK maturation and activity, macrophage production of IL12, Th1 development and maturation of CD8+ T-cells. Also implicated in the differentiation and maturation of dendritic cells and in the suppression of regulatory T (Treg) cells development. Acts as a tumor suppressor and plays a role not only in antagonism of tumor cell growth but also in stimulating an immune response against tumor cells.
Miscellaneous:
MISCELLANEOUS: Deletion or rearrangement of IRF1 are found in preleukemic myelodysplastic syndrome (MDS) and acute myelogenous leukemia (AML).
Subcellular Localization:
Nucleus. Cytoplasm. Note=MYD88-associated IRF1 migrates into the nucleus more efficiently than non-MYD88-associated IRF1.
Sequence:
MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAIHTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDDHSSYTVPGYMQDLEVEQALTPALSPCAVSSTLPDWHIPVEVVPDSTSDLYNFQVSPMPSTSEATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQAIPCAP
The following text describes a protein:
Function:
Has a role in the ecdysone induced cascade; probably indirect control of 'late' ecdysone genes.
Sequence:
MLLTTGHARARPEQQQASADEPLEAKPEDGHSLTAPRPADDELATVAPTTTPVPAVAITQGATTGAATEATHSQPVVTAVPATSSTSTSTTVPAPLLPAAPEQPEYLKHCFYADEHLCMYGHDGQGNEAPDVLGHISTTPESDSQGIGLQVNASQGNSQNLERNANSCQCHEHPAKANSWYCCNISQMSMISSCSNISKWTNLHVRNLTVRTIDLSNPIFRSLQSLAVTDGNITRLINAFPRHSALKCLNISNNNISEIPSRMFKDVPHLEFFGMSRNNLSLVPHHNQNKNITVDISGNMRMLCNPLNEIINNDSFNFVNPKHSYCLYNATHEWFQSTDLVSVEQLESTKRCMTKCPVIPNYGSCKCRFESIMIIQDDQSKPKCHVDCSNLGLVELPPRLPDNTFVLNITNNKITSLGDHFQTNPTYHNINRLVADNNQISSIYEFEGTKFIENFQRIYMRNNSLSKIPEYFLNNALMDTGRRIYLAGNKLQCDCNSAKTLQNWLKERSTDIPDYMEIRCRNIPQSVIELQEAKLCQSPPDWTDYIYYLIAAEVILLLGLITKVSYDYWVFKTSGYLPWPASKMPKLPCDWLCES
The following text describes a protein:
Function:
CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition.
Subcellular Localization:
Nucleus.
Sequence:
MTSIVKLEALSGAKDDGPLCYLLQVDDVYLLLDCGWDENFDLLYIEAVKKRVPYISAVLLSYADTSHAGALPYLVTKCGLTCPIYATGPTCKMGVMYAYDWLQSHKAVEDFSLFTFDDVDASFERVQQLKYNQTVSLKGDSGLQIVPLPAGHIIGGAIWRISKAGDDEIVYAVDYNHKKERHLNGCLFDAIQRPHLLITDAFNAQYKQPGRKQRDEQLVTKMLRTLQKGGDCLVVIDTAGRVLEIAHLLDQLWSNKDAGLGAYNLVMLSHVASSVVRFAKSQIEWMSDKVMRSFEQGRFNPFQFDHVQLCHSHAEVDRIRSPKVVLCSDISMECGFSRDLFLEWCSDTKNTIILTGRSGERTLGSKLIRMAQGQQRGKSSLVLEIKRRIRLEGAELEEHRARRLHEHQEEARKKMEANRRRSGLAGAKADASDSESDDDDVIASAVAAVQKATDAVTAAAAAAGAAAPIASTPRGSSTGGGGVPIPTTPLEAKPFPAHESHSSTAVSAYDIIQKWEHTQKASFFKQNKKSFPMFGYVEEKVKWDDYGEVIRPEDYMMDAVAPPVVASNGQSGVANGGLNGVSAMLAEAKIKADPDLAAEAAAAAGAADSVDSLLAEEEWPTKCLKYITKLEVMCRVEFIDFEGRSDGESIKKILSQIRPKQLIIVHGDKAATQHLADFAKTVVQGSIFTPKLGEIVDATVESRIFQVALSDALLSSLSFQKVKDAELVWLDAKLLKRVAEDGTRDEEEDEPEEEPEEMEADEQSPGGPVDEMAPPAHKRMRSKRAADRFLLDALEMGAIPPHQAVFVNEPKLSDMRQMLQAAGHPAEFSAGVLHISGVASIKRNDAGRFHVEGCASEKYFQIRDLIYKQFAIV
The following text describes a protein:
Function:
Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MAAPGPVASPRPGGEPILKDVVAYVEVWSSSGVENYSKTFVNQLLSMGARVSKTFNRNVTHVIFKEGYQSTWNKAQKYGVKLVSVLWVEKCRLSGKHVDESLFPAINTHEGLSSLIKKKRKCMQPKDFIPRTPENDRRLQKKIEKMANELNMQKTSIDNDIPVLLFEADGSLMYSPTAKIKDQCNAMEKRLQEMKDKRENLSPTFSQMLALNSDPSSSGVALNTSLNTSHSDEFISDVLNTSFDDIWRNSEQRKRTVKSEKHTREANTDTCLSSPISKTASCHLFDSITPQRSKSNLTAENRNFQNTLTTEVLTPEKTHFEEVSKKLFSDKDYLNPLAIVESHSTKSPRPTNTSEKQLRSLMHINSPLKEKSRKKKSTIKFATPKVHRDKAENFLELMTTPVKVSPACEEAIYEDYFSPTNLKEGNSKNCTSKVKQILESPSHLNSQKSVYRSKKRSILENSDYPNFSKRIKLIETSDNLVEECNCTLKKLPNSERNMSLNCNPYSEIPNANEILGCYNEIDSQERERNIAIGGNNCLHTADESVLMSQYLESGSCDTLVSLERDSKEVLTNKKESIIPMNIQKKENINSEVFNSCESKKQDFNFIFKSDAALEKSVKEMENPSRYIQSVESGKAKLNILEDISKGFMDQKIKSLEESKKTRKVKKPTRTLVMTSMPSEKQNIIMQVVDKLKDFSISCEVCESTTHVVAGEPRRTLNVLLGIARGCWIVSYEWVLWSLEFGHWISEEPYELSNNFPAASICRLERHLSTGQYQGDLFASQPVMFITAASEPPCAKLRELVQLCGGHVSRSPFVASIYIGPYRGKKLPQIKHLSEKWILDSITQHKICPCENYLMP
The following text describes a protein:
Function:
Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
MEVFPFLLVLSVWWSRTWDSANADSIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTLSVRPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENNINKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNMEISNLYIYDTVLLLANAFHKKLEDRKWHSMASLSCIRKNSKPWQGGRSMLETIKKGGVSGLTGELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNMRGVVLRVVTVLRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRAEKTVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTIGNTVADRGYGIALQHGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQCDLYSSVDTKQKGGALDIKSFAGVFCILAAGIVLSCFIAMLETWWNKRKGSRVPSKEDDKEIDLEHLHRRVNSLCTDDDSPHKQFSTSSIDLTPLDIDTLPTRQALEQISDFRNTHITTTTFIPEQIQTLSRTLSAKAASGFTFGNVPEHRTGPFRHRAPNGGFFRSPIKTMSSIPYQPTPTLGLNLGNDPDRGTSI
The following text describes a protein:
Function:
Tyrosine-protein kinase receptor that functions during early stages of neuronal development.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MNKYSAFIVCISLVLLFTKKDVGSHNVDSRIYGFQQSSGICHIYNGTICRDVLSNAHVFVSPNLTMNDLEERLKAAYGVIKESKDMNANCRMYALPSLCFSSMPICRTPERTNLLYFANVATNAKQLKNVSIRRKRTKSKDIKNISIFKKKSTIYEDVFSTDISSKYPPTRESENLKRICREECELLENELCQKEYAIAKRHPVIGMVGVEDCQKLPQHKDCLSLGITIEVDKTENCYWEDGSTYRGVANVSASGKPCLRWSWLMKEISDFPELIGQNYCRNPGSVENSPWCFVDSSRERIIELCDIPKCADKIWIAIVGTTAAIILIFIIIFAIILFKRRTIMHYGMRNIHNINTPSADKNIYGNSQLNNAQDAGRGNLGNLSDHVALNSKLIERNTLLRINHFTLQDVEFLEELGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYGKFTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLKTWHEGHFKASNPEM
The following text describes a protein:
Function:
Catalyzes the dehydration of D-mannonate.
Sequence:
MKQTWRWYGPNDPVTLSDVRQAGATGVVTALHHIPNGEIWSVDEIQKRKAIVEEAGLEWSVVESVPIHEDIKTHTGQYDLWIKNYQQTLRNLAQCGIYTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFELHILKRPGAEADYTAEEIAQAERRFATMSEEDKARLTRNIIAGLPGAEEGYTLDQFRQHLATYKDIDKAKLREHFAYFLKAIIPVADEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVETVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTLREENPKTFHEAAHLHGDVDMYEVVKAIVEEEHRRKAEGSDDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSK
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus.
Sequence:
MASASARRSTLAAIDANQNNGQIASALPVPSSAVKSAKTLSSGSFQPRASMIPQQSNPVRQVSATNANIRDAQHSSQHSGPVHPASQSGRRGDSGMYAGRQSVASAGRQSVAVAATPNSRRSMVGRLSIAPGNIGNTGGSGVRETRPIKDKHYKTRMGLTVKEHLERTGFTMAGWDANKGVHEPTQSAFVGMFKHIYATCIDTNFVMGVDGKKFEDEVLTLMKEIKYPAADELSKTKLTAAGSQSHWPYCLAMLEWMVNLGNQAETIGTGPRSRPDEIEDLQSLFFPYLWDCYDRFWQNEDTYPEEHAKLGVRFEDKNAAIELELKELQQEHRKLESELADYLNNDSPLKIERSENDMLTKDISKFHKYYDDVLVPKLDKTKKAIERLIKEIALAEKEIDDKTKRRVDLQEQVNAQEMSAEEYERMLAERNRLTKRLEVLGEQNKKAAGDGWSLEIAIAKKQADTEDRISKFNPLARSISLLPYRLASGSVIEELELTPSNPSTMLQAGVDIKGSFRRQIETLRSQEADKYRHASKKRLAMQEEYEKLQETLSEQETQLASDRERCEALSRQAAEYEKSCKTVQERYKADEGKLEKSTYETEASGSVHLQQAESRLTSLQLTAEHKEDEWNQQRSRMDEDMLNFVVLLSKMKGDVTGQLREIQAAVALKSRDD
The following text describes a protein:
Function:
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein.
Sequence:
MKIKELQKTVNIAWSPAKQQQILLAAGTAAQQFDSNANSTLELYSPNFSDATYDLELRASVSSQYKFQKLIWSPVGPHPSGLIVGGCEAGQINIYSADKLLAGKEEPLLKRQDKHTGAVSGLDFNPFQNNLLASCASESEILIWDLNNPETSMSPGTKTQPLEDVKNVAWNRQVQHILASVFSTRCVIWDLRKSQQIIKLSDSQSRVRWHAIEWHPEAATQVWLASEDDQAPVVQLWDLRYATAPAKTYQIHERGVLGMSWCLQDNDLMVSCGKDNRIYCWNPNTKIPEGEILSEVATTASWYSDVQFCPRNPALIASASLEGAVSIYSLHGGTHHLVQTANKIADSFPGMDQFAQEPIPQQATQVVYHDLAHAPKWMKRPCGVAFGFGGKLVSFNGTSKTVKVQQLTTESALVDRANALERSLVDANYSDYCRQRADETPDQHGRYIWYFIKANFELNPKEEMLNLLGYNKDDIDSKFNKFIKETDGNSHSDVDTLTTRISTLTHTQDNKFDGNAIDSQNHNDFATPPRPQFKVPSGDHSDSLIAEAILTGNVDAAVELCLEAQRIPEALIIASTAGIETLNRTQTRYLLQQKNELSHVISALVSRDWLDFVNRCTVDSWKEALVAALKHSERKVVDICERLGDRLLSECASSAEFTRNAMLCYICAGSIDKLVTAWYQLKRLEQQNPGYKPNTTELQDLAEMVMLMCKSLEQQGISVDLAGRFAGFLTEYGGLLASQGALTAALQYITTLGGGAAASESDVLQSLRDRINNAVNLDYTQPQAAVAAAPHGYQPTRGRGSFSQPQPSAPMPYGQPPNQYAQPSWPAQVPPLQTSYPGAQQPQAPPQIFNPQPVKPEPLAQPPRPLSNASSSGGPPPAGGASSSGGSGLSGRSKYVLDPSVAAPTSSYGMPYNPVPAPVPSAVPFGGGGVPGPAPQPASVPTYNSNAFNTNPIAAAQPYNPSPLMPAQQNQFVPGVNPIETMPPPAVPPVIQNVQRNPTPPPGWNDPPALKSSRAPKPKPVVEPSAAIFHPLFPVDPNQNQNGYVDPSQYQHAAPPGGVPNTYYNPAAFNNNPQQQQQHQQSYLQPQQPAPGIQQPNWQGQQQTIGYTEQPAPIQQQRQPAPPKEKPPLPEEYIYLQTVLEELKNRCLGATNDPRTKRKFVDVVKRLENLYDCLRDGKLTPTTVQYLNQIVQYIQISDYANAMEIHTQIAFGTDFAQCAGFMQGLKVLLQSASELQLVLR
The following text describes a protein:
Function:
Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3' (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
PVYVPTTRVPSMLPSLPYLPSSGSSQQASPVSSHSIWTQPGAESAAYNPGSSHPPVSPRFSFSTSTPIPSTSSRDAAAAYSSSLSLSANGREQYSRGFGSSYSSPYPAYVSPEMATTWTSSPFDSPMLHNLQSRGTPAAARHANIEFFDDYSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLFKPQRRLSASRRVGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKTKTPAGPSSSESLTPTTSSTSSSSSATTTEEMRPIKTEPGLSSHYGHPSPISQAFSVSAMSGHGSSIHPAISALKLSPQAYQSAISQSPQASSKQDSWNSLVLAENHGDIITA
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB46.
Sequence:
MAAIYLDSSAIVKLAVREPESDALRRYLRTRHPRVSSALARAEVMRALLDKGESARKAGRRALAHLDLLRVDKRVLDLAGGLLPFELRTLDAIHLATAQRLGVDLGRLCTYDDRMRDAAKTLGMAVIAPS
The following text describes a protein:
Function:
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
Subcellular Localization:
Cytoplasm. Nucleus. Secreted.
Sequence:
PVRRMERRTATGKTSQRSKRLGVISRSFILCNSKTSDDGSSPEEKYPDSTEMEESGREKSKRNLRPGALSAADSVEQTTAPEPPACHQLRAPGDDRRGIRRTFSIKESSIWRLCVATGEEGLRNRMCDDDDAEAPPNNCMNRYTYRDIIEPSKEWIGKVLREEGNYRHDLHKDSLTGSKKSPAQTHCSPTLALPAADRDNLQPLSYHLTKTHTGKNGCSQEPILEMMGDGTGTWEGDKTDQVSQSKMSCIRTRSNSTSVNPYWIGDLDALIIKTPEVYQTNNNQTDGNPGFYGNRKSLSQQLEFTNGIAQVVPRPSRSLSSAHLVNSTSSTQAFVICNIVLMKGQGKGLGFSIVGGKDSMYGPMGIYVKTIFPGGAAAADGRLREGDEILELNGESLHGLTHEDALLKFKQIRKGLLTLVVRTSLRVGAVPSSGVVPHLCRSRSLSSSACISRGSTDITDYSFLAHPVKPKDRIMMEITLHKEVGVGLGIGLCCVPSSEGCPGIYIHTLSPGSVAHMDSRLRCGDEIIEINETVVYNMTLNEVYTVLSQCSPGPVQVIISRHPDPKVSEQQLKDAIAQAVENSKLKKDRSQWSMEGAFLGLKKMDPCYHGKQKCDKCLERSFSHLNNRRVQKVMTRSCSDSSYNHCSFCSSGSSSHTHQHADLKSRVHSVDVPMPTSRGHNHNDKDNAPNRCDAKGCSQQAADLSTKHTKVSKPKPPPPPRRYFKQSDISHEEHFYGPAGDSKDSPVKDDGWHPSYINCQASVLHARLKTNALLYLSRPVSSTTEYCSRQADNQEYEDEDCAQGKRPTLRRQAHVDLFLDQTQDPWVRISDSIEGQLSSVIMSQENGQADLNGSSISQEKDASEAGSTAPALNTTKLEESPNLKKGPPVAPKPVWARQSLRGMKSGRLSEPIKPVDHKSSDVGKTFGVSLRATSAKTNLSFKEKLHSFETLSSPESPERGARRLGSSSSLPVMEKTPSRNDTACSIKTDSHMSSKATEAKPPDNSKSPEPTTEQLPSEGITFSAVITESCTINKPAIISIDSKPVEDAPVVLAEPEVSSSLSESYSFPSPRRCSSTKGITSEKTPQMEDENELQKAPSLRTRSLPVSASQPPEPSVLKVFDGESLGKILSFSNQVSNALMRSMRSLPQSPCTWPSNPWNPGPEEDGGADKDPPSTTGDNSHHEKGFSVSLAELRECTIGIVEEKKEEGKRELSSSMTSSASAQSVISIIPPEEIEKMIEEVKALDEETLKQFEDIHVVILHKEEGAGLGFSIAGGIDLENKMTTVHRVFPNGLAAQEGTIQKGDEVLSINGQTLKDVTHSDATAVLRQARMMKQAVVVVCKSKENEKSASETSDCSAAASSASLADEPGEILTVTLEKNAAGVGFSLEGGKGSIHGDKPLVINRIFKGGVAEQGEIQQGDELLQVQENSLQGLTRFEAWTIIKGLPEGPIKVVIKRKKADTE
The following text describes a protein:
Function:
Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
Subcellular Localization:
Cytoplasm. Note=Colocalizes with RAB11A on cytoplasmic vesicle membranes.
Domain:
The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.
Sequence:
MERKEGPPCEVRLPTPGAEREGPIHSELGAFGETASGTIKQGESSTDAKKEEIDEELDPRIQEELERLNQASEEINLLELHLNEARTAYRRILSESARRLNGLATQLGACIDKARPYYEARRLAKEAQQDTHSAALRYERAVSMHAAAREMVFVAEQGVTADKNRLDPTWQEMLNHATCKVNEAEEERLRSEFEHQRVTRQCHEAEAKVQTLQKSLKRFIIKSRNYFELKAQLNTILEEHKSRVTSLENSVAQAKLRYSGTLRNLEQISEEIHSRRTQSSVLSQRAPPLGAEAPPPVKDGETGPPADTVSLLSLQTIASDLQKSDSVEHLRDLTDVTSLDGRETGTVESGGSRERGADRETEGAFRHHRSVSL
The following text describes a protein:
Function:
Probably accepts electrons from YgcQ/YgcR and reduces a quinone.
Sequence:
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGVTTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSLRCL
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MELLNDMALFVEVVKARSFRGAAATLDMPNSTLSRRISLLEKEIGLRLLNRTTRRVELTEAGQLYFERCKRIVDEARLAHEQLGEMLARPSGLLRVSLPVDFANTYLAPLITEFAQHYPGIDFEFDLTPRRVDLVSEPYDLAIRIGESAASHMIARPLARLHGNLYASPRYLELNGEPREPADLARHQCLCQTRVSTWTLHNGTQTVEAEIAGRFHLNSIGMLRRLATLDMGIAFTPQEIVADEVASGRLRRILPQWQGLPMTIYAVTETRLLPAKTQRFIEFLRERLSRG
The following text describes a protein:
Function:
Essential for plastoquinone-9 (PQ-9) biosynthesis through its interaction with the solanesyl diphosphate synthase SPS2. Binds to the hydrophobic solanesyl moiety, which is generated by SPS2, in FBN5-SPS homodimeric complexes to stimulates the enzyme activity of SPS2 (Probable).
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAAASVLLLLPSPFLRPSSPAHRARCGIATTTTTSTSGRRGLFLFASRCRPGPRRRAASAAVPPEHGLSQPQPQARAVGSYEAALGDAKDALYAALEGMNRGIFGMTSEKRSEIHALVELLESKNPTPEPTDKLQDKVDGCWRLVYSTISILGKKRTKLGLRDFISLGDFFQMIDVKEEKAVNVIKFSARALKILSGQLTIEASYKITTKTKVDITLDSSTITPDQLMNIFQKNYDMLLAIFNPEGWLEITYVDESLRIGRDDKANIFVLERADPSEV
The following text describes a protein:
Function:
Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus.
Sequence:
MANSFASKTFTALSDLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPTHFVNATSWGSEGYIRSLSDSFRVGECVTIENPLIQRKELEREEKFSPATPGNCKLLLSENHSMVKVCSSYEVDTKLLALIYLPVKESRDFYSLGDIIANGYSLDGRIINVLAAVRSVGEPKYFTTADRRKGQMCEVKLYDETESSFAMICWDNESILVAQSWVPRDTVIFASDVRISFDKFRNCMTATVISKTIITTNPDTPEANILLNFIRENKETSPLDDEIDSYLKESIDLNTIVDVYTVKQLKAKASKNEGKTDTFYGILYAYISMLNIDDDTTTVVRHRCSGCGYIVNERSSTCTACNKDSLEFKSVFLSFHLLIDLTDHTGTLHACSLTGGVAEETLGCTVNEFLAMTDEQKTALKWQFLLERSKIYLKFFLSHRARGGLRISVLSCKLADPIEASRNLSGGGNI
The following text describes a protein:
Function:
Component of the glyceraldehyde dehydrogenase which is involved the nonphosphorylated Entner-Doudoroff pathway. Catalyzes the oxidation of D-glyceraldehyde to yield glycerate. When the artificial electron acceptor 2,6-dichlorophenol-indophenol (Cl2Ind) is used, the enzyme shows a broad substrate range (glyceraldehyde-3-phosphate, formaldehyde, acetaldehyde, propionaldehyde and isobutyraldehyde), but is most active with D-glyceraldehyde. It is not known which acceptor is utilized in vivo.
Subcellular Localization:
Cytoplasm.
Sequence:
MYPPEFSYVRAESLQEALKFLEGNDNTRPLAGGQSLIPMLKLRVLSPDYILDINRLNELNYVKTSLNGVSIGALTRYHDILSNDIVKSKVPLMHHATRTIGDMQVRNMGTIGGAISNADPASDMPVVLTALNATIILSSASGSRSVKALDFFKGPFTTDTNKGELVTQIEVPVLDGYKTVYKKVVRRAGDYALASVALAIKLKGNEIEDIKLAYGGVHDKPFRAMEVEKNVIGKKLNDDLVKDIASKVSSQINPPSDHRGSSWYRREVVKVLTMKAFKEVA
The following text describes a protein:
Function:
DNA-directed RNA polymerase-associated factor required for the transcription of viral early genes as well as for transcription termination. Within minutes after virus entry, recruits the core RNA polymerase, the early transcription factor (ETF) and other enzymes needed for transcription initiation, elongation, and termination thereby allowing synthesis of early mRNAs which are extruded through pores in the core particle. Recruits the multifunctional OPG102 protein, with poly(A) polymerase-stimulatory, cap nucleoside-2'-O-methyltransferase, and transcription elongation activities. Interacts with nucleoside triphosphatase I/OPG123, a DNA-dependent ATPase required for the termination of early transcripts. Acts as a transcription termination factor by binding, together with the capping enzyme/VTF, to the termination motif 5'-UUUUUNU-3' in the nascent mRNA. Involved as well in the packaging of RNA polymerase and other components needed for early transcription in assembling virus particles.
Subcellular Localization:
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.
Domain:
Interacts with ETF via its N-terminus and with DNA-directed RNA polymerase via its C-terminus.
Sequence:
MDSKETILIEIIPKIKAYLLDANISPKSYDDFISRNKNIFVINLYNVSTITEEDIRLLYTTIEQNIDADDQTLVAIFSYIGYKFEQAVKEEISTSLSFNDKNTTDEMTYNLYDLFFNTLDMYLRQKKISILVNDDVRGDVIVSYKNSDLVSSFNAELEPEIKKIPFNMKNLLPYLEKNLDQLRFSKKYLDFAYLCRHIGIPISKKKYNVRYVFLYKIDGLSIPIIIKDFLDVKYVYLENTGKIYKNSFSEDHNNSLSDWGKVIIPLLKDRHLYSYIFLSSYHLHSYYTDLIARDEPVFVKRKKLDIIEIDEPEAWKRDVRVEFAPCEHQIRLKEAMKVDANYFTKINNFANEFIYYEDGVAYCRVCGINIPIFNLDAADVIKNTVIVSTFNKTIFLSEPYSYFVHSQRFIFNIIMSFDNIMKSQTWVMKYNINRLILNFLIDINSRRQEYEKKFSSEIKRGLFFLRLSANLFESQVSSTELFYVSKMLNLNYIVALVIILNSSADFIVSYMTSKNKTVEESTLKYAISVVIYDFLVKTRICEKGSLDTIVLFTDVYTSIMPEELDLHFQRITLELRKLVSIQRSALEPNYDVESRGEELPLSALKFFDTSTIIVKTMAPVHTYIEQKIVAPTPSVEPTDASLKNFKELTCDEDIKILIRVHDTNATKLVIFPSHLKIEIERKKLIIPLKSLYITNTLKYYYSNSYLYVFRFGDPMPFEEELIDHEHVQYKINCYNILRYHLLPDSDVFVYFSNSLNREALEYAFYIFLSKYVNVKQWIDENITRIKELYMINFNN
The following text describes a protein:
Function:
Putative sodium-dependent amino acid/proton antiporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MENDKREKSDKAQKMESERSCLLSSHDAGKGGSSSVSSASFNFINSIIGSGIIGLPYSMSQAGLPMGLLLLILVAFITDYSIILLVRGGNLSGTHSYQSLVRSTFGQIGYIIVSVLQFLYPFIAMISYNIIAGDTLTKVFMRIPGVGPGNILTERHFVIAMSTVLFTLPLSLYRDIAKLGK