The following text describes a protein:
Function:
Probable component of the nca-1 sodium channel complex, a cation channel that regulates neuronal activity by transmitting depolarization signals to synapses. Regulates the transition from slow to rapid forms of locomotion. Required for localization of nca-1 along axons and in non-synaptic regions. Contributes to endocytosis defects in synaptojanin mutants. Involved in the control of anasthetic response to halothane.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHVRYLQHEHTGTVQLLLMPLSTAASFKSAKWTEEEGEEECDSVPLPIQTFLWRQTNPFLGDKIGKLHEASCVTFERVVVQNILHGLSPSLSNALASVSRWKLVRAALPHVIQCCGSLLLANVGEKKLPTSLQKILYILHWMLIDSSSECIENASTKDDRSVCQSRTQGLFNISSIQLFIYLIAPLADVISEEEVVDNIRLESGLKVWQAIWQFRQPDVWCFSAPVKQRRDELPQITFARRQNPAQLDTQGIYLGKDENTVRRPSIVPPPKPPRTDVTVLNEKRKLEEEKMKMKEDYVAIEIEAPSLKPNDLLIDMSQGVRNKEFERTSSIVRSVSEYKTNLCGQKEKLATVSKSRTSDAFDSSPTSDSSANMLEEVEGIKFSENENCSLSAVFFSSDQAPLVNLSDICSGFSIEEPHDSTQSSVEVPQHPVLESSMFLSTTSSASDVPPFVLTRASTAEDTTSSCSQQTVIPLAMPVTTETTTLPVTLPKSALTKTTNENRRTDHQRMPSTQKSVSGSTDDELDEGSFSDPTIASYLDVAVIRALLITHWQEKGVYWALSYIHNRLIEIKAYMIIRKSTRQRSNSLPSGERKLSVAPEQLTNPVWDDLKIENKPEEGRSHLHVAFNDTERRKSSDNCLAPHPTTNSRRSSLNTLSRRGINRSNPSLSNSVEVLSIRDDAEDDVSNISSKSIEKENTKLNAVFYPEALGSTNFIEKDGKISATVIVQTVNQVMDRCTGVRQCELALNIADVLLGTPLEQTETFFVQLNIMVFKIYLCLGCPHGCNEGVKSPHGDFLRAKAKAILAGLERVQPDKFKNILNDYVDNYGTQQVIDLLHSITSFCRSELTALDGRRASESRVPSYRNTFNEKDKGIEGRIINATYKTLITKISVISAELSLPENMSLQQDVRLLVNFVQEHHGNPFRRVGLSALKDATCKNPTTSDFHTKEDQTGGSPGAQSQKQSNDQASLRRGLFKKKNEKSGGTTTGNDDSEGDSSPSTPRTVSSMDDGVSPLASTSYYKKKSAPKLHFAFGLLKSVKPDMDEEISDNENEEGTSNEEAGLPQRRPLRQSSKQVKARLPIDSKGGMRLWGTYVPPPNYIDAKGIFDGARRFAFLLETARPGTFPDAPLIAAIMHLKSPVLARASLLLECANLVSRCNRGQWPEWIRSSHHRTFSLGGALANRGTPSATRRMHSLQRQAGRYFYQWGVQIGEHISKLLELSENKSKKTLQMEDTIEDFFDDGIVNNQNGEKCPIALQFIAVLLLQEITAFLRETFKTIPRSKNSKPQTGNSGWDKLLSHRRWSILSNTFNAQQTGSVNSITEINSSIHLNDKERRISFSATEEDSPRGSKDAIDEINAVDKKGSIHMQVVRPPSLSARLFSRQSTHEESGGSAQGSTKSTTYVPETGRRIATGRQRLLKRGSPMATGTQPSLESSHKRKSFRNRKQSKQAHLEEEEKSDGGSLTSQQSPIVQRMRAASMRQSSNFLALFHHAIPEFLDAGATHILSARESLKPTDDGLQSPVESVHPVIIPHSNHGSAHSQQPVVLKSSMDDEEQHMLSNLPWIKVLIKFSNSFDLECNHVGVCSAKCFQRVHRQCFRMIESLSTLYGMERNVSTRADKRNLLADNWQAKQQALRKQTETNSARASIHARQSTAVPRRESAMVGQPEFASKAIKMMLMEKMQQEKEKEKEKEKEEKDALKKQSVEQDHSSTDTEEDAQLPEKNKPMLTYLRSLVLQLVHSPISSVLKCCLLLSVEQHKQMIEVCWKMLIHEDPHVVASAASMFIVASVKKSEESLLIIKTALDSQDPQVRTSGIQRFYTLWRNRFHAWLKMEDGAQASFKVPPPGIDFTLPSPAIGQSQLPVVDPPWMPHLKTKIEELSLKEEEHATSQTIMTMTRTRRKQKQEMVKRAVREAEERQSEQRQLFRLRSSAIVSLAAYEPALFHHQQEQTEESDNSHQHARHVMPVAQPLFPSALLSVVPQIIELLDDPQVDNNGVSVGDVAKKVIWTCIVEDPSLFLRHFLEKLTNRDRQVLISEYAPTPAYEALMSQLRKLVLRFHPLPSQAAHSLLNYLFGFVMHYVRAQCEGSEKAIGMALSICWLLSPNIHGLYFKDLKQTLKKEQCDQALMITANVPSAKKIIVHGLDSTSGGIPSQFPVHEDTQFHQILNDSLEFFNIDEDDLNCFYLTDTKTGVIHLPAAYVRDYYFFHRSFYPQLTLVKLSPEVAEKKMKETAFHQKFIECGKVLLTHNILKYSPQHVIAQRVFFLHDEFTHLPSFPRKSLETCFGMYFGPGGEQLKAMESMHKFVWAKMMSDMFEKMENAFMFADLHLFINVINGIMIMHCEDVLILRRCAATYISISIHFNTLFASQGFFLIMPTLLRCYSQRQTNKVFCGVVEFICRQFYTLHRKPFLLQMCGAIANIIDNSSNDFEINPMRVKAKYWFNLIKKMEEITDEDPLDILGLVPYEKPLKALDLCYRDDPNTFCALTDAMASCICVCAFSPESKRSHHMLLIMQAMLPHMMKRLEEETLQSGNSPAAVKHEISQWITMAVEMKALINSCEQLVRGPTRAFDLVNSVSERGKSFVADSPQFFDPPTTNEDENSRPYHLKEKRSTAVAWEAAEVEEQQKETYRRPRDTLLQLIAAYIEMASVRLKELTKLGANLEHAKIPDVLDHKCYVKLGEVALALLKVAPYDLSTTTCHGLQKYFQIILPVTDWSIESNRSALNIILRRLDKTLSKIAKRQSFRKRAIWIALSSWINGICDTLNAFPYIAHLHPLRTITQLCLRMMVGDPCVEDSAASTALHPTTVLHPTPPPQTFANAVLRLTTILMQALGQFAFSLDFVTSTEGMGVSSERLEAVLCHVLIPLFLRIPNNPKEQSIFQAKDLSQCLTVMQNAISPPLVKQQAPPLISTSTLTTTFIRGAQDVTGRQGSVSVTDRGHSATVSTHRIVRESICQAIYLGLKVLMLTFGKLLAPMWPRVARIVKDLLAKKPGAPTSMAFVDFLLHSNLPISLFILPMIQNKMKQKPGTDQEAAWQTEILEKLDAKSHNIVPPSILLVKCYQELQQLKEELTMKPIEMTRSYTPTMADPHSDSSAASTAPRGASSRQSIDRRTSVHMKKVLPTMKEDIPEDPEDSEDVIDSNSTGQVTSRISKSPSIPLNKTHQSSRTRSVSGFGMWRSVRRKSRHVSSAEESSEERGSVELHDVGHHSALHEPNRTPNRRSTEALVLPLHESIDTNRHRFVSFSTPKKTHEVSEDVFQITEQHQLV