lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDWNDVTFEDLVDALKEVDWSIPPRPLGEFFGNFSAPKNDSKWEGRLRCNLYYYRTNYVLLAGSVFVLAFVRNPLALGAVTLTGLSVACFNDSFAITLSEKLTRGISQVSPTIGRKLRAPVNDKPRGQSRNRTIYICGQDRRICATILASAGALLWWKSSAVVTICGASILALSLPILHASFRTPNVKSRLNRIREEIRDVLKGYKEM
The following text describes a protein:
Function:
Catalyzes the reduction of a 3''-keto intermediate during the biosynthesis of 2'-deoxymugineic acid (DMA) from L-Met. Involved in the formation of phytosiderophores (MAs) belonging to the mugineic acid family and required to acquire iron.
Sequence:
MAVIQLASHFSRSSKFVGSDSTIVPTRILPRPRGITRSAMASPSGSSRSPKIPEFPAGSGGRPVPAVGIGTASFPFVAEDVKNAVLAALELGYRHLDTASVYPSEHLVGEAVAEAARRGVIASREEVFVTTKVWCTQCHPDLVLPSLKDSLQNLQMEYVDLYLVHWPMSVKPSKPHFPMKREDIVQMDLKGVWQAMEECHSLGLAKMIGVSNFTTKKLQGLLAIAKIPPAVNQVELNPAWQQKKLIELCKEKGIHVTAYSPLGGQSRTSKINAVLQSEILKEIAEARGKSVAQISLRWIFEQGASMVAKSMKKERLQENLEIFDWELTDEDRFKITQIPQYKKVTVSAILCPEGVPGVDLSEVDVVET
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MSFFRVRLERSAIGLSSKVRSVLHSLRLTKRHSVVYCDVNPINAGRIFKVKELVSVSTVKQKLAAGQEKKSLASSSGFTVIHRYNNGLKELNNMFES
The following text describes a protein:
Function:
May play a role in placental development.
Subcellular Localization:
Secreted.
Sequence:
MNLRKFLGGTVLVAFMLFSYSEQNQVNVLCSTDWFMVTVHPFLLNNDVYVHFYEVHLGLGCPPNHVHPHFYQFHYRVTECGIRIKAVSPDVVIYSSEIHYASKGSSTKYVIPVSCAAPRRSPWLTKPYSAKAPSNNMGATPKNDTSYHVFTLPEPSEQPNCSCPPYVYNQKSM
The following text describes a protein:
Function:
Acts as an activator of the phospholipid scramblase activity of XKR4. This form, which is generated upon caspase-3 (CASP3) cleavage, translocates into the cytoplasm and interacts with XKR4, thereby promoting phosphatidylserine scramblase activity of XKR4 and leading to phosphatidylserine exposure on apoptotic cell surface.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus.
Sequence:
MSRCRSSSVRQISISSEPQRCFFLKLEWAEDLGSGFVIFLCDGESAWSGEVSEEDVSREAREMEMERDRYVCDLQLALTGAPSGSGASDEGEFTFQLTPERPGRPQLQLSYEKVQKDISFRLGVVDLQPVPEPTEVIRELITHGLEQSSRLQASNQHLLEENQKLRREQQHITEEMERYVKGKEALERDLYSRFVLVLNEKKAKLRALQQRVRELEEAEEERSPRKKKADSEDHEAVEAAADKSPDEESDYGGSTEDEQEAEPKRLDPKPPTEEMPECSPMDDSLNDITDVAPCRKRRHRHLQQLEAQAKRKTLEQQHRSREKPVEETKAATSRTSSVPVKPANTAANLDPDELFDDI
The following text describes a protein:
Function:
Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Subcellular Localization:
Mitochondrion outer membrane. Cytoplasm. Note=Colocalizes with HIF3A in the cytoplasm. Upon phosphorylation, locates to the cytoplasm.
Domain:
Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
Sequence:
MGTPKQPSLAPAHALGLRKSDPGIRSLGSDAGGRRWRPAAQSMFQIPEFEPSEQEDASTTDRGLGPSLTEDQPGPYLAPGLLGSIVQQQPGQAANNSHHGGAGTMETRSRHSSYPAGTEEDEGMEEELSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFEGSFKGLPRPKSAGTATQMRQSASWTRIIQSWWDRNLGKGGSTPSQ
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MIGSKKSKEANVFKEIAENFEQLTKNPERFLQPQPEQVNAIEQLIQQTYAVSISEDVANKKELLPELVLEQMDEEQIWQQLEIRNELVFQQVLEQTARLTAMREQHLGIELDDGEEIEEEDEVIQAEDSGDEEQDEESDFSDEDGGLQKQKTAPPKDKRNKRLRNSVVDDTFFKLEEMNEFLEQEDAKEMRRLNSKKRVEQADDIDHFAEDFGLGEDEEDDEEGNVNYADFFDMNEELTEHSKKINKGKQKDFFNENESENENEPDEDANPKEGDSDQSEGDEGDDEPENDQDPDEAASEIDESEFVAKSGIEPASDSDSDSEKEEEEPQPTEPPSQSSNEMREARLFQRIRDYEDIVLGEKPWQLKGEVKAANRPQNSLLEEILDFDSTTRPTAPITEEDNRSIEDIIKQRIRDKAWDDVERTVRPVNTPQEYRKQLVLDQEKSKQSLSQIYEAQYQREMEKLDPNRDADDKTGPEPKEHQEIKRAMRSLFLKLDALSNFHFTPKPVAPEIKIVTNTPAVHMEEVAPLAVSDAKLLAPEEVFRGPKHAPLGKTERDRTDKNRERRKKKQKQRAIHSALEQRELQRAKEGKAPTKKEADAKLLKTITKNRNVQKINASSNDQGALKSSKAFFHKLQDTAAATASKKRPKKDTAKADAKKLKL
The following text describes a protein:
Function:
Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Binds and bends DNA repair bubble substrate and breaks base stacking at the single-strand/double-strand DNA junction of the DNA bubble. Plays a role in base excision repair (BER) by promoting the binding of DNA glycosylase to its substrate and increasing DNA glycosylase catalytic activity that removes oxidized pyrimidines from DNA. Involved in transcription-coupled nucleotide excision repair (TCR) which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Required for DNA replication fork maintenance and preservation of genomic stability. Involved in homologous recombination repair (HRR) induced by DNA replication stress. During HRR, binds to the replication fork with high specificity and stabilizes it.
Subcellular Localization:
Nucleus. Chromosome.
Domain:
Both nuclear localization signals 1 and 2 act as a monopartite signal which binds to the high affinity site on importin-alpha; Both the spacer region (also known as the recognition (R) domain) and C-terminal domain are required for stable binding to the DNA repair bubble. However, both domains are dispensable for incision of DNA bubble structures.
Sequence:
MGVQGLWKLLECSGRPINPGTLEGKILAVDISIWLNQAVKGARDRQGNAIQNAHLLTLFHRLCKLLFFRIRPIFVFDGEAPLLKRQTLAKRRQRTDKASNDARKTNEKLLRTFLKRQAIKAALSGNKQSNEELPSFSQVPRKETEDLYILPPLEDNENNSSEEEEEREWEERMNQKQRLQEDFFANPSSVDIESEEFKSLPPEVKHEILTDMKDFTKRRRTLFEAMPEDSSDFSQYQLKGLLKKNDLNKCIDNVRKELNQQYSGEVQAQFESEGGFLKEVETRRLVSEDDSHYILIKGIQSKQEEKKVDSPPQSITFNSSQTPKTYLDLKLASAHKTKPLQTSSAEAAPPSPRTLFAIQEAMAESWDHEKHEKPSVSGCEAEGNVSPRTLQAIYQVLAEDEAGESNKIKVVLQSDEERKPKTKVLVISSSDEEDDCLNYQDGTKTTLGASLIKSISPSSMQCQESTADSLPNYTRSKPVSQIEEPMADHNLQGDNCNVPNAKDKLIVPPSLGNVDKPIILSNTIPVNSEFRIPLLPVNMSMRETVIIPNNTGSLGSSRYISLERDATKQGFSDNPVGDLVRSPDEPALNASSALSDRKTSATQSLLCNNIECTEQSMVQGCSNTLDVTQTTQPSGGSEVNKPAEYNPQDKKVFGSNDSSAMYVPMTPESIIVSDEEFVNEKEDSDSDDSFIEVDSEFSTSNSQHVVFKEPGDTRETATNFQAVEEGNSGSQDIPLEHDSGEPHEQSNSEESKDLDDVSNEWQDISVEELESLENNLYVQQTSLQAQQQQQERIAATVTGQMCLESQELLQLFGIPYIVAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYKNFFSQNKHVEYYQYADIHNQLGLDRSKLINLAYLLGSDYTEGIPTVGYVSAMEILNEFPGQGLEPLVKFKEWWSEAQKDKKMRPNPNDTKVKKKLRLLDLQQSFPNPAVASAYLKPVVDESKSAFSWGRPDLEQIREFCESRFGWYRLKTDEVLLPVLKQLNAQQTQLRIDSFFRLEQHEAAGLKSQRLRRAVTCMKRKERDVEAEEVEAAVAVMERECTNQRKGQKTNTKSQGTKRRKPTECSQEDQDPGGGFIGIELKTLSSKAYSSDGSSSDAEDLPSGLIDKQSQSGIVGRQKASNKVESSSSSDDEDRTVMVTAKPVFQGKKTKSKTMKETVKRK
The following text describes a protein:
Function:
Putative transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSLLFDPGFVILREDQSVKLFNIILVMSQVFGGLAVLLVTIWMSKFESGFAWNEDPDKEFNYHPTFMIMGMVFLFGEALLVYRVFRNERKKFSKTLHVILHSCVLVFMLMALKAVFDYHNLHKDPSGNPAPIVNLVSLHSWIGLSVVILYFAQYIVGFITYFFPGMPIPIRQLVMPFHQMFGVLIFIFVSITVAMGISERAAWKHTCWTKEGQMCAQQATSSFVGVFTFLYTVCVLLLVLNPRWKRQSLPEEEGLHHLTSSHSMSD
The following text describes a protein:
Function:
Component of pre-mRNA cleavage complex II, which promotes transcription termination by RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MEDGAARQDACREYQSSLEDLTFNSKPHINMLTILAEENLQFAKDIVAIIEAQITKAPSSEKLPVLYLVDSIVKNVGGEYLAEFAKNLVTSFICVFEKVDENTRKSLFKLRSTWDEVFPTKKLYLLDVKVNSLDPAWPIKPLPPTVNSSIHINPKFFKQTEEAPSPQPAPAQPPPPVVTPKPPSATGQSSLTQEQLIRKQLLAKQKQLLELQQKKIELELEQTEAQLAIGFNLQQAPAGPPPAAPSLAPKPLSQSTSVIRPWIPPQPPTDPKLPTRDPRLNRPAPLTPAQSKEPPAPRKEVSPSVQNLAIIPEKRLPEKPVKPDRTRTFRKDILDEKSKNKLPKSVQNQREVAGPDPKVPEKKDPRLKKRPLERGPEPKEDEVKDKKRSSDKKERDDTPRSNKGKLHNGAAAKHEDVGDKAEPKSGGNARTHARKRTRSRSRSPNASPKRKDRRSPKSRPRSSSPSPHKPGKPRRVRPDNLTLNKPGHDERLAPKKNQADGRRPKRPAEERHGESRDSLRINDGGAKEGKEGHRWRSGWENKHLKSEESHPKAGPLRHKPYGGPARPSTPRTPKHRLSVDANLQIPEVLNSASKKDLLMRASKRVESGEISQEDFLNMAHQINHLFQYQEEKQLRSESWDGPGEFPTKKQTGQAHVSMPHPHMDPAELSYYEHKSKLKKTQVNHRTANEEWESQDSLEGGGDAEQAMHPPTHKFSRPPRDRPGERQSKEREDSRPPLAPMIEDYNHGKEFPTLKSLPDLRFRRRADPRKSSEREWTSPLERQLYKEKKGGYDAPRRYEARHSEPRRPEGAPLPEALPHRKCPSPVGLEGLAPHFRREPLSPPRQVNAPDSPVARFESPNSEHSDDGPLILDPHMPPQHMLTGAPFRPHGNSPGHTPPHDGVHPPRYGGPALIGPARPHPPGWTGGHIEEPHHQGPGRFDDGGPSHLMVDMTEPPQGPGRFGAPIGQQPVSGRGPGPIDGPVQHFEPSGPFGGPMGFHQQQRPPHFEDLSNQLRPPRLDNNVCFDRPNQPGPHFDMANAPVQGGGAHYDFIPGQQGPPRFGPQPNLQPHVRQMAPDVYNHPVPIQQNFAMTLQPFQEPMNPQFPPAPMATGNFNPHIGQPGPGSFYNPPAPNINMQQPVMASMNAPFLPPNQVSFEPQFPQAAASGEHFGQVDVESLLSKLISTGIIKPSQPDPALPASSGEPAAVAPPAAPEPEEEEDQEVEENDIPDLTGFSIDHMKLRYESVVTKLYTGNQCCLCSMRFSATQTDLYADHLDWHFRQNHADKQASKKVTHRRWYYTLTDWIEFEEIADLEERAKSHFFEKENEEVVQKTQAAAKEKEFQSVRATKDQVGESCEICQEPFETYWVEEEEDWFLKNAIKVDEKNFHPSCFEDYKKVSLPFLSVLCSSIFLRSPSPPPPPPLQSSYLDATPSPSKLMTEHPLGAFKTEQESTSCALEATSVKQEVEPPQETDCEPSCSEETVGGAPEAVVDSVPSEDPA
The following text describes a protein:
Function:
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome; This protein binds specifically to 23S rRNA.
Subcellular Localization:
Plastid.
Sequence:
MTSFKLVKYIPRIKKKKSGLRKLARKVPTDRLLKFERVFKAQKRIPMSVFKAKRVLDEIRWRYYEETVMILNLMPYRASYPILKLVYSAAANATHYRDFDKANLFITKAEVSRSTIMKKFRPRARGRSFPIKKACVI
The following text describes a protein:
Function:
SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity).
Sequence:
MKILAIRLKNLASLAGEQEIDFTREPLSSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSASSKVPDGRNELSSNDERNLLRRGCASGYAEVDFVGIDGHRYRARWETRRSRDKADGALQKSQQSLQDLETQQMLAANKKSEFREQLEQKLGLNFAQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAGTERLQGLQARLQEARERQAQADNHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWVTHQGQLATFVQRRQRALESQAQLPELEKSLAHAGEPLERLQAQWTALHGSEPDDLAARLVELRRQTDSLERQQALHKEWQQVLDQRAGLARRLGELDQRMVEQEQALLDLKRQGSQCAEEVKAAEQALQVTRELLQRQRLARSASVEQLRAGLVDGEACPVCGSQEHPYHHSEQLLAALGEHDDQEQVRAEQSLERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLDQWTLPEELRLLQPSAQLEWLAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGESIEQRRQQQARLQQIEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLGLSEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRERLAASEQAYLETYSQLQADNQRREQSQALLAELERARAEFRRWGRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQRGGSELGLLVVDTEMGDELRSVYSLSGGETFLISLALALGLASMASSKLRIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHERIPVQVRVQREGNGMSSLKVVG
The following text describes a protein:
Function:
Component of an histone acetyltransferase complex.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MAIARTGVFVDDYLEYSSTLPAELQRLLNTIRELDERSQGIINQTRQQTNYCLGLASQSQGSRKYNYDDDEAFEKLRKEIEGNQDNALSLCTEKVLLARQAHDIIDSHIKRLDEDLTNFAEDLKQEGKLPADEPPILPPLPLVLKTEKRKAPYVTPQSKKFEYRDWDWDRERDRDYDLMPPPGSHKKDFASPVDVDQPIDPNEPTYCVCHQVSFGDMIACDNENCQGGEWFHYTCVGLTPETRFKGKWYCPTCRQLPH
The following text describes a protein:
Function:
Acts as an activator of the phospholipid scramblase activity of XKR4. This form, which is generated upon caspase-3 (CASP3) cleavage, translocates into the cytoplasm and interacts with XKR4, thereby promoting phosphatidylserine scramblase activity of XKR4 and leading to phosphatidylserine exposure on apoptotic cell surface.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus.
Sequence:
MERKVSRIYLASEPGIIHFLQIAWEKTLGSGFVITLTDGQSAWTGTVCESEISQEADDMAMEKEKYVDELRKALVSGAGPTDAYKFNFSKESCHFSFEKNLKDVSFRLGTFNLEKVASPAEVIRELICDCLDTIAENQAKNEHLRKENERLLRDWNDVQGRFEKCVSAKEAVEADLYKRFILVLNEKKAKIRSLHKLLNEVQELEKNMEHEKETTTCSEMTADRDAAYDESTDEDSENVPDPSGSAPATLRRDDSIISSPDVTDIAPTRKRRQRMPKNLGTESKMASQEKQHQEKAKHEPPLPEALRKEHSSAENMSLETLRNRSPEDLFDEI
The following text describes a protein:
Function:
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
Subcellular Localization:
Cytoplasm.
Sequence:
MSELKVAALRALKLMDLTTLNDNDTDAKVIQLCHDAKSPVGNTAAICIYPRFIPIAKKTLREQGTPEIRIATVTNFPHGNDDIEIAVAETKAAVAYGADEVDVVFPYRALIAGNEQVGFDLVKQCKAACGDKVLLKVIIETGELKQEALIKKASQICIEAGADFIKTSTGKVPVNATPEYARMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQQYLAMADEILGGDWADSRHYRFGASSLLTNLLNTLEVTDQKADPAAY
The following text describes a protein:
Function:
Structure-specific DNA-binding protein with a preference for cruciform structures. Also binds single-stranded DNA (ssDNA). Functions together with top3 to maintain genome integrity. Essential for proper meiotic cell division. Required for normal S-phase progression and DNA damage response.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNQTTTLSTELTELGVRVQNRWLQSLLDYLAKKHSTGANTTPQLVMQYLVASDIRESTTSEGAAPYIVSEQHNVRIENTMLLQIVRVREIGISIVNQLEYLNDLEELKKLKGQKVIRLVHDESGDEEQNDDDGLTEAQDAVQKGSELKKMCRLILEDSNGQRFWGLERKPIKGIQLSTKLGTKLLVKNVLVRRGVLMLDPNNTTILGGSIEEWDKDYFPKRLIEELKGELSKTKA
The following text describes a protein:
Function:
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
Sequence:
MLQSNEYFSGKVKSIGFTSSSTGRASVGVMAEGEYTFGTAEPEEMTVVSGALKVLLPGTVEWKVYTAGEVFNVPGHSEFHLQVAEPASYLCRYL
The following text describes a protein:
Function:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRQLPTALEVRGGPSIXFIMARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERAXIIGSFSPSSTKALFRATKSAIKRAETFISTVQIATPTAPNKLTPPIRLEFSLRSSPAAYKAVGQAGNHISFVEALVRMSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
The following text describes a protein:
Function:
Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MNFLPLWRYQNQLIDGAIVTLELTVIAALAGLVIGVAGAVALNGRITPLRWLVRGYIELFRNTPSLIQIFIVFFVLPNFGLKLPAFEAAAVALSLYFGAYSVEIIRAGLDSVPKNQIEAGQCLGLSGWQVFRHILLPPALRNAYPAVTSQFVLLLLGTSLASQVAADELFHVAGFIESRTYRSFEVYAVICAVYFAMAMSFKALFAIIGLAAFRWPRRR
The following text describes a protein:
Function:
Acts as a scaffold, mediating interaction of ROPs with different proteins.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MQTPKPRPGSLEVPQKKSPASTPKTARKLKTSESDPVSSPNTKIRTPKTQSPKVVADRRSPRTPVNEIQKKRTGKTPELASQISQLQEELKKAKEQLSASEALKKEAQDQAEETKQQLMEINASEDSRIDELRKLSQERDKAWQSELEAMQRQHAMDSAALSSTMNEVQKLKAQLSESENVENLRMELNETLSLVEKLRGELFDAKEGEAQAHEIVSGTEKQLEIANLTLEMLRSDGMKMSEACNSLTTELEQSKSEVRSLEQLVRQLEEEDEARGNANGDSSSVEELKEEINVARQEISQLKSAVEVTERRYHEEYIQSTLQIRTAYEQVDEVKSGYAQREAELGEELKKTKAERDSLHERLMDKEAKLRILVDENEILNSKIKEKEEVYLNLENSLNQNEPEDTGELKKLESDVMELRANLMDKEMELQSVMSQYESLRSEMETMQSEKNKAIDEALAKLGSLTEEADKSGKRAENATEQLGAAQVTNTELEAELRRLKVQCDQWRKAAEAAATMLSGGNNNNNSNGKYVERTGSLESPLRRRNVNMSPYMGETDDELSSPKKKNGSMLKKIGVLLKKSQK
The following text describes a protein:
Function:
Transcription factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Also plays a role in DNA break repair, participating in the DNA damage checkpoint response. Promotes transcription of PHB2.
Subcellular Localization:
Nucleus.
Sequence:
MKTSPRRPLILKRRRLPLPVQNAPSQTSEEEPKRSPAQQESNQAEASKEVAESNSCKFPAGIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPGLRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGVLCQQKRETCADGEAAGCTINNSLSNIQWLRKMSSDGLGSCSIKQEMEEKENCHLEQRQVKVEEPSRPSTSWQNSVSERPPNSYITERKRMTLKDIYTWIEDTFPTLSTLPAGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELPLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIAPKVFGEQVVFGYMSKFFSDFGTPITSLFNFIFLSLSVLLAEEGIAPLSSAGPGKEEKLLFGEGLSPLLPVQTIKEEEIQPGEEMPHLTRPIKVESPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRERSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSEPASQLSYSQEVGGPFKTPIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTPQGASDPLPDSLGLMDLSTTPLQSAPPLESPQKLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTEGLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ
The following text describes a protein:
Function:
May have transport activity.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MSEKIHITQNSGNVDHTVEALGHAISGGVAGMAAIALTYPFSTVSTRLQVQQKKQQQGQQSEITTVPYKNSIDAFKRIIKEENWRTLYSGLKSALIGIGASSFVYYYWYTLLKSISLKLKNKQELGTIENLAIAALAGCANVLTTLPIWVVNTRLQINSDKGIVGQFKYIIKNEGFGGLYKGLIPALILVSNPSVQFVSYEKLRALWRRQSGRTKLGGLEVFILGAIAKLIAGIVTYPYLLVKSRLQSQSGNASNPESQQQQYKGTLDAIGKIFKSDGFLGFFKGMPSKMVQTVIGAAFMFLVKDKVVIHAVAILFYLKRLLNKNNKRV
The following text describes a protein:
Function:
Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Represents a key regulatory connection between the folate and methionine cycles.
Sequence:
MSHHRGRAPPLGHCCQPLGMGSQETGSLRLSVPSSISCRNPAMVNEARGSCSEGSSSGSEGSKDSSRCPTPILDAERHERLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMIIANTAVDYCGLETVLHMTCSQQNRDEITSHLHKAKRLGLKNILALRGDPIGDEWEEEENCFSHAVDLVKHIRSEFGDYFDICVAGYPKGHPEATSFEEDVQYLKEKVSAGADFIITQLFFQADTFFNFVKACTAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVTMCKELLASGLVPGLHFYTLNREVATMEVLKRLGMWNEDPRRPLPWAVSAHPKRRVEDVRPIFWASRPKSYIYRTQAWDEFPNGRWGNSSSPAFGELKDYYLFCLKSKTPRTELLKMWGEELTSEESVFEVFTYYLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLKVNQRGILTINSQPNINGKPSTDPIVGWGPSGGYVFQKAYLEFFTSSETVEALLQVLKKYELRVNYHIVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYHLVNLVDNEFPLDNCLWQVLEDTFELLSSPVQ
The following text describes a protein:
Function:
Probable transcriptional factor. Binds to the promoter of the SQUAMOSA gene.
Subcellular Localization:
Nucleus.
Sequence:
MENSKWEGKRNMMEADMEEQDDEEDEDFVEDTKRKRVLTRSGRKVSMGEGPRQPSCQVEDCTADMVDAKAYHRRHKVCEFHAKAPAVPIGGLLQRFCQQCSRFHQLAEFDDTKRSCRRRLAGHNERRRKSAHDSPGEGSS
The following text describes a protein:
Function:
DNA-binding protein, which similarly to histones, may compact DNA into chromatin.
Miscellaneous:
MISCELLANEOUS: In yeast, DVNP5 binds to histone binding sites in chromatin and displaces nucleosomes, and impairs transcription and inhibits cell growth.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to condensed chromosomes. Localizes upstream and downstream of transcription start sites of chromatin.
Sequence:
MAAMKKAMKVKKSAKKSAKKSGKKGGMKKKAKRVSKVARGKRAKSSVFRGTKERTSGGLTKNSLVKNKQGRVVSKKQSEHGKKIFKKHGLQKWIDAVTKARKALGIKGFQAVGGSSAKGKILLAKSRSFYKK
The following text describes a protein:
Function:
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Sequence:
MSDFPELEDFSNVAASNDPQADFLARERALLGDEFGAPPENYQETIQVKQDDDDQFGLGDFSSAPIDHHPQPAAPPPVSTTGAPDELASFQDQYPDISHDIPDQTNGFDAPAPSLYANQSSAYATPAVYAQTQTEEESPFIKEWRTNQAEEIRVRDERSAAKREETIVAAEKAIDEFYHGYNTEKQKNIAKNKEEEAKFIQSRSDKLAQGTTWERIAELIELQDSRSKTCGKSAKDLARFKEILLNLKRDGQNAPGAAGF
The following text describes a protein:
Function:
Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein.
Sequence:
MAGQNFRTFFQFPSLNSVQWYPGHMAKGMHKMQAVLVRCDCVLEVRDARIPFSSRNEKFSRILAGRPRVLILNKADLSAKNTRKIIPAALRSMNEHGISSDNKKGFFRIMVIGLPNVGKSSVINAIRRIRKNKGNAAHVGGVPGITRAVQTNIEVCSNPKTFLVDTPGIMPTYVRDVEVGFKLALVGTIKDHLIGEEHIADYLLFTLNRQKQFSYVEYFGLDDCTDDIDQLLVHIGHKMGALRKGGVLDLKQAATRFLTKFRHGHLGTILLDKIHKTT
The following text describes a protein:
Function:
Protects the virus against cell antiviral state by blocking host interferon signaling. Mechanistically, targets host phosphorylated STAT1 (phospho-STAT1) for degradation, thereby inhibiting the interferon alpha signaling pathway. Plays a role in the inhibition of host apoptosis. Interacts with and down-regulates the expression of host TXNL1. In turn, inhibits TXNL1-induced apoptosis through the BCL2-BAX-caspase 3 pathway. Inhibits host apoptosis also by negatively regulating host CacyBP/SIP. Promotes viral replication by activating the extracellular signal-regulated kinase (ERK) pathway.
Miscellaneous:
MISCELLANEOUS: The protein V from strain B1 contains one putative zinc-binding domain on its C-terminal region whereas protein V from wild-type avulavirus strains possess two.
Subcellular Localization:
Host cytoplasm. Host nucleus.
Sequence:
MATFTDAEIDELFETSGTVIDNIITAQGKPAETVGRSAIPQGKTKVLSAAWEKHGSIQPPASQDNPDRQDRSDKQPSTPEQTTPHDSPPATSADQPPTQATDEAVDTQLRTGASNSLLLMLDKLSNKSSNAKKGPMVEPPRGESPTSDSTAGESTQSRKQSGKTAEPSQGRPWKPGHRREHSISWTMGGVTTISWCNPSWSPIKAEPKQYPCFCGSFPPTCRLCASDDVYYGGDFPKSK
The following text describes a protein:
Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis.
Subcellular Localization:
Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton. Nucleus.
Sequence:
ISFLNLQVGFNADEAHNIVKECIDGVLGGEDYNQNNINQWTASIVEQSLAHLVKLGKAYKYIVTCAVVQRSPYGFHTASSCFWDTTSDGTCTVRWENRTMNCIVNVFAIAIVL
The following text describes a protein:
Function:
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
Sequence:
MIIESRIEKGKPVVGMETTVFVHGLPRKEAIELFRRAKEISREKGFQLAVIGILKGKIVAGMSEEELEAMMREGADKVGTREIPIVVAEGKNAATTVSATIFLSRRIGIEVVVTGGTGGVHPGRVDVSQDLTEMSSSRAVLVSSGIKSILDVEATFEMLETLEIPLVGFRTNEFPLFFSRKSGRRVPRIENVEEVLKIYESMKEMELEKTLMVLNPVPEEYEIPHDEIERLLEKIELEVEGKEVTPFLLKKLVEMTNGRTLKANLALLEENVKLAGEIAVKLKRS
The following text describes a protein:
Function:
Putative quercetin 2,3-dioxygenase.
Sequence:
MTATVEIRRAADRAVTTTSWLKSRHSFSFGDHYDPDNTHHGLLLVNNDDQMEPASGFDPHPHRDMEIVTWVLRGALRHQDSAGNSGVIYPGLAQRMSAGTGILHSEMNDSATEPVHFVQMWVIPDATGITASYQQQEIDDELLRAGLVTIASGIPGQDAALTLHNSSASLHGARLRPGATVSLPCAPFLHLFVAYGRLTLEGGGELADGDAVRFTDADARGLTANEPSEVLIWEMHAKLGDSAT