lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the hydrazine synthase complex that catalyzes the condensation of nitric oxide (NO) with ammonium to form hydrazine. The gamma subunit catalyzes the first half-reaction, i.e. the three-electron reduction of nitric oxide to hydroxylamine; it may obtain electrons from the triheme cytochrome c kuste2854. Is involved in anaerobic ammonium oxidation (anammox), a biological process in which nitrite is used as the electron acceptor in the conversion of ammonium to dinitrogen gas (N2) and water; this bacterial process has a major role in the Earth's nitrogen cycle and has been estimated to synthesize up to 50% of the dinitrogen gas emitted into our atmosphere from the oceans.
Subcellular Localization:
Anammoxosome.
Domain:
Consists of two alpha-helical lobes, each of which contains one c-type heme.
Sequence:
MAREMRLGGKERMKTGVVKIGLVAALGVVGLISAGGVYAGQPRVISTIQTGATWEPLGREEPLTVPEVHFRVKHSPFKSELVRYGQFQFNDAAWSLQGSYSCASCHYERGQTTGLIWDLGDEGWGSWKNTKYIRGGRYLPPFRHEGFTGHPDEIVGATSSLDRVCGRDPGFVFRSENFSPMRLEALICYIRALEFTGSPFRNADGSLTEAQKRGQKIFEDPKVGCLECHPGDPMDPRALFSDAQTHDVGTGRVGVNGFRSTPGKVFNISALEAGEDPYGVESNTPIIGLDLVKEFDTPTLRDIYASGTYFHDGGARTLMDTINNTVNDKDMHGRTSHLKQQELQDLVEYLKAL
The following text describes a protein:
Function:
May play a role in development of the heart.
Subcellular Localization:
Nucleus.
Sequence:
ESLSPSRGVAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLANRSASLLKSYSQEAAIEQPMAPRPTALSPEYLSWSSSSPYSTVPSYSSSGTATAAQGVNMANSIASLRLKAKEFSLHQNQVPTVN
The following text describes a protein:
Function:
Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
ESHIPKFFLNQKQECGCKSQRGYISGSDKCPRLSTTEFADVAAETYPLKTKLRYECDSGYRRRSGNTLTIRCQNVSGTASWVHDELVCIDEKFLFSRNHTAKLNPTQQPARQTQSPAPPKQANNSSFCGMPQTVPHASLSVHQIYSVGQVLHFKCPTGYNKQLPTTGTITCKNVDGRIKWTPADRPCTNDSGPINKQLSHLMEAVIFFILLLHSAVFL
The following text describes a protein:
Function:
Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd.
Subcellular Localization:
Nucleus.
Sequence:
MEQVDSSTELHLNRKDLAALAEDVVKEEVILESSSHHHHHHHHQLDTKVRMVTSSSNDNSGSGGASGGTSGAGGGNGGGGVVSVPVSLPIGSMITGTTFNVITPDQLPPHFKPMLCVDNNGYLSGSTVSMGNDLKTIVIQQQQTQPGGGGGGANNAGTNTTATNTIGLNHDGSGSNNSHDSLATLEHAAGGASGVGGGGGGTGGGSSGWSENPSTQHNEVFQIRCKTTCAELYRSKLGSGGRGRCVKYKDKWHTPSEFEHVCGRGSSKDWKRSIKYGGKSLQSLIDEGTLTPHATNCSCTVCCDDEAGESASGPVRLFTPYKRRKRNQTDLDMESGPKRKRNTHHSNNNNSNTNNNNTSGSGANNCVDVTAAVAAATASVVDENNMFLSEENITSKDEPWAALNDSLDTSTELVDQSQMGNTYERETFVVNINDGSSIAVLDTSQSMKNIEHVYCTMVKATNDFKRMLNDMKQSFERRIEVLQKERDAAVSAMRVQVHADIDDPNISGSLHGNEIISAKKCANCNREALAECSLCRKTPYCSEFCQRKDWNAHQVECTRNPQTTTQQVMLLIDDQS
The following text describes a protein:
Function:
Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.
Subcellular Localization:
Nucleus.
Sequence:
MYEYSFNPNIDHEPGSVESQQSTIYSDSDDSDDSFLDDEVIPPKEQAMRKIEFALADIKRQMDNKEKSLTLRISTSKSHFCLRYTAKRKGKLDRDLHCLHQVYDLLENDKRSTKRELYYEHKAVYGNQKYLDSSIKSICELLNESRANLNILSCGRGIIRGAITFLVENVGVIDARVQEVLITDALLFSNIISEADFILVVEKDTTFQKLMDENFQAMFPRGILATSKGYPDIATRNVLKMLSEKRKFPIYGLFDADPHGIEIYLTYKYGPTKEFAEGRGAFVPTIEWIGLFPTDFHRFTIDQSQCLPLVRTDFVKIEKMIPRSIQLGEIVVTRELDWMIQNKFKMELESINMCGQEYMARFLIAPRVMSIEKEIPIQPETIINEYHEDSQCSLSTDDDREAKDDDYIDSDAEEKFQNMIDNDSD
The following text describes a protein:
Function:
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MAASLRHMAHFQKALLVARSAPRISTIVRATSTLNDGASKVPDHSMHFKLERLWAVGMLPILPASYFIHGPVMDAVLTVALTLHIHWGIHGVVYDYARPYVIGEAAAKAAHVGVYLITGLLLGALLHFNTNDVGITKAFELVFSL
The following text describes a protein:
Function:
Induces sexual development and ascus formation. Also involved in calcium homeostasis.
Subcellular Localization:
Nucleus.
Sequence:
MNPYVSYPEIHMKRNRTGSINSNPLYIPNPNVEPTPKPTKRRTKTGCLTCRRRRIKCDETKPFCLNCTKTNRECEGYPNSAAQMQAMGSVSPPELSVHSAQQPLIPTSIASSSAQTGDTFSGSSQSNFNTNDLNQMTSSSNLSTVTPIKQDHQKPMNLQGFPSAYQQHQYLQSNHNVPTNNSSSATSSTKPSVQSVGQASYPFLSSVSNFPSNFNSELFPFYFHDVVPSICAFEFDNNIALHFWSVTVPQFAQSMPCIANSLMAFASIKKLDVFGAYSHLTRALRCPMPGPNSFEYLLVSAFLTLTQLNLPAYDLNFCNNFIRKLSWSSSTKSNYVSLLIAMVVRELVFAILPRGCIWGFNGKPLSEVSVSRSHAPVSDSLFTIGLDILSQPTLSDDLHRERMVAWRDEYHVHLYSASRSPLTKVIDCVGHAVTKNNNDVLSGLQQLMQEECTDIAVLRTSYLCVLSLQNVFASNSKEFKLRAQIESHFGRLMLEHFMDCNVLNRPVL
The following text describes a protein:
Function:
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Subunit of the 40S ribosomal complex.
Sequence:
MNEMPSPPCLSSPRPTKGKGFSFHHPEAELPPSPPPPPGPRQQALPGPCPHRLSPSPLGRTHARGRLRAQPGKPLKRRERRAAALFPCGRRAEREAEAAPGGSHHSAPPLTAAMAEEGIAAGGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK
The following text describes a protein:
Function:
Catalyzes the hydrolysis of phytate (or myo-inositol hexakisphosphate, an indigestible organic form of phosphorus that is found in many plant tissues) to myo-inositol and inorganic phosphate. Dephosphorylates phytate in a stereospecific way by sequential removal of phosphate groups to produce myo-inositol 2-monophosphate. Also shows phosphoanhydride phosphatase activity and hydrolyzes the distal phosphoryl residues of GTP, the 5'-beta-phosphoryl residue of the regulatory nucleotide ppGpp and tripolyphosphates. Does not split most phosphomonoesters with the exception of the synthetic substrate p-nitrophenyl phosphate (pNPP), 2,3-bisphosphoglycerate and fructose 1,6-bisphosphate.
Subcellular Localization:
Periplasm.
Sequence:
MKAILIPFLSLLIPLTPQSAFAQSEPELKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQSGQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNANVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKREKQDESCSLTQALPSELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFYLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHDTNLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL
The following text describes a protein:
Function:
Involved in rRNA-processing at A0, A1 and A2 sites and negatively regulates telomerase.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MGLAGVKKKQQIGVDPRNSKWAKDTNRLGFKLLSSYGWVNGNGLGEKQHGRIHNIKVSLKDDTLGIGAKATNDLEWSGLGEFNAIFGRLNGDESAYGVYAEKAKVQQLTYERQSANEKGLKSLELSRRFVLGGTFTSEFSEWMQKAEEDEDRVCEDASSSDEAKREKRKKHSSKKKSKKKTSTGSALDPKKLEKITKKKKKEHKKKDKESSSKKRKSGSSDKEEKKKKKIKLKDKPESTSSVEKVKEGNRPASIHFHTRRKFLAQKRAAVSDPVALREILGIKG
The following text describes a protein:
Function:
May play a role in ribosome biogenesis.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MAAARRLKRVAVSQPGFLGLKSNVKPSELVSSRRKRVNKNKKKNWNRHSDIHDVEDFLEDIRHQERTTGGLLSEKPDDSLFFLDVEAEPVKAEKGKRRVQRPLRIDLILQHDSMVPAPKNVTAYQQPNAKKLRRIAQKAEQLAAKGVLPRRQRRLLSRRPAEKTVKKAEANNNPDRDFYAMWGEEKVTDSADPWYLQQTGKKLVQRPEKLNQKPSVLPAVEVIAPGGSYNPDFLSHQALLQEAHDVEVQKQKQEDKLQRQLAFRKEDRATEVQTIISAVAACLYEDEDEAAAPNEDEANSALGAIAVAAKKTERQRKKEKAEKMKTQQQQASRRQTERQQQLFQLRSIKSSIKQQELQTKARRMKRKARQEAQKALPRRLGRLKYAQDLEVQLSDELAASLRQLKPEGSVLKDRFKSLQKRNLIEPRERAKFKRRLKVKYVEKRAFRQIT
The following text describes a protein:
Function:
Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
Subcellular Localization:
Cytoplasm. Endosome. Nucleus.
Sequence:
MEAIAKFDFMASGEDELSFHTGDILKILSNQEEWLKAELGSQEGYVPKNFIDIKFPEWFHEGLSRHQAENLLMGKEIGFFVIRASQSSPGDFSISVRYWSHKGVHTHACRCAHRQTVFQRKERRHNQGRSLDLDRRTQGGPPREVPSGTAGEEIRPLMNRKLSDHLPLGTQQFHPHQQLPPQFPPGPQPPPQQRYLQHFHQDRRGGSLDINDGHLGIGSEMNATLMHRRHTDPVQLQAAGRVRWARALYDFEALEEDELGLRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMMR
The following text describes a protein:
Function:
Transcription activator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences. Transcription activator that plays a regulatory role in grain development. Positively regulates grain size by promoting cell division and expansion, leading to increased grain length and width. Positively regulates the expression of genes promoting cell proliferation. Activates the expression of expansin genes to promote cell expansion and grain size. May promote grain size by activating brassinosteroid responses. Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable). Component of the miRNA396c-GRF4-GIF1 regulatory module that plays an important role in grain size determination (Probable).
Miscellaneous:
MISCELLANEOUS: Plants over-expressing GRF4 exhibit increased grain length, width and weight. Plants silencing GRF4 exhibit dwarfism, delayed growth and inflorescence formation.
Subcellular Localization:
Nucleus.
Domain:
The QLQ domain and WRC domain may be involved in protein-protein interaction and DNA-binding, respectively (Probable). The C-terminal region downstream of the QLQ and WRC domains is necessary for transactivation activity.
Sequence:
MAMPYASLSPAVADHRSSPAAATASLLPFCRSTPLSAGGGGVAMGEDAPMTARWPPAAAARLPPFTAAQYEELEQQALIYKYLVAGVPVPPDLVLPIRRGLDSLAARFYNHPALGYGPYFGKKLDPEPGRCRRTDGKKWRCSKEAAPDSKYCERHMHRGRNRSRKPVETQLVAQSQPPSSVVGSAAAPLAAASNGSSFQNHSLYPAIAGSNGGGGGRNMPSSFGSALGSQLHMDNAAPYAAVGGGTGKDLRYTAYGTRSLADEQSQLITEAINTSIENPWRLLPSQNSPFPLSSYSQLGALSDLGQNTPSSLSKVQRQPLSFFGNDYAAVDSVKQENQTLRPFFDEWPKGRDSWSDLADENANLSSFSGTQLSISIPMASSDFSAASSRSTNGD
The following text describes a protein:
Function:
May play a role in plant immunity.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MKDCENHGHSRRKLIRRIFWSIIFVLFIIFLTILLIWAILQPSKPRFILQDATVYAFNVSGNPPNLLTSNFQITLSSRNPNNKIGIYYDRLDVYATYRSQQITFPTSIPPTYQGHKDVDIWSPFVYGTSVPIAPFNGVSLDTDKDNGVVLLIIRADGRVRWKVGTFITGKYHLHVKCPAYINFGNKANGVIVGDNAVKYTFTTSCSVSV
The following text describes a protein:
Function:
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Domain:
The BTB/POZ domain mediates the interaction with some component of ubiquitin ligase complexes.
Sequence:
MKFMELGFRPDTFYTVESVRSVSSDLLNDLVIQVKSTKYLLHKFPMLSKCLRLKNLVSSQETETSQEQQVIQLVDFPGETEAFELCAKFCYGITITLCAHNVVAVRCAAEYLGMTEEVELGETENLVQRLELFLTTCVFKSWRDSYVTLQTTKVLPLWSEDLGITNRCIEAIANGVTVSPGEDFSTQLETGLLRNRSRIRRDEILCNGGGGSKAESLRWWGEDLAELGLDLYRRTMVAIKSSHRKISPRLIGNALRIYASKWLPSIQESSADSNLVLESVISLLPEEKSSVPCSFLLQLLKMANVMNVSHSSKMELAIKAGNQLDKATVSELLIPLSDKSGMLYDVDVVKMMVKQFLSHISPEIRPTRTRTEHRRSRSEENINLEEIQEVRGSLSTSSSPPPLLSKVAKLVDSYLQEIARDVNLTVSKFVELAETIPDTSRICHDDLYNAIDVYLQVHKKIEKCERKRLCRILDCKKLSVEASKKAAQNELLPLRVIVQILFVEQARATLATTRNNITTNETAVLKRSFTTRREEGGQEEEERDETKPSGGFLQSTPSRFMALCAIPRQPKKLLCKLLSISRSLSQRI
The following text describes a protein:
Function:
Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis.
Subcellular Localization:
Cytoplasm. Nucleus. Synapse.
Sequence:
MAVPFKLSCSLTGHESDVRAVAAGLFPEGSIITASRDRTARLWVPSSDSEPGYQEAHCMSGHQNFVSCLCVLPPNEKYAQGLILTGSNDYKIHAYTLESPLPVYVLTGHKNAVCALASGKFGTLLSGSWDTTAKVWLNEKNVMTLQGHEATVWAVALLPTQGLMLTGSADKTIKMWRAGRCERNFTGHTDCVRALAVLSEVEFLSASNDGTVRRWLTTGDCVHQYDGHVGFIYSISLLGNGQDFVTSSEDRTVRVWTDGQCSQTITMPAQTIWSVACLTNGDILVGSSDGMARIFTREESRVAPQDSQQAFENQVGAFAMPAKTQTFDGIKMEDLPDKSDLANQGTKEGQTKLIRNGKTVEAYQWNMAESKWSKIGDVVGSEGDDVTPSSGKVHYEGKEYDYVFDVDLEEGRPNLKLPYNASDDPWLAAQKFIHDNDLSQYYLETVANFIIKNTKGVTIESSAPRPDFVDPFTGGSRYVPGSRGDPSLPSVGSGGGGGGGGGGGHDPFTGGSSYRPGGSGAAQPQATAVTQSTNQYFPKKDYVSFDSANTQAILGKITQLNSTIDASCRLDDATLSHLESLLACMSNGQGGTPTGQQLAALWSLLQWPQDQVFPGLDLLRLAIRNPAVNQHFCNSQDGPGFFSHLFSLAANSSPAANHMLLYRALCNCFTQSEGKSLLVAQRETIGVSAMGSLTITNKNLRIAVATLVLNYAVLLQGGSDVEAKSQCVAMAITQLGEEKEPEAQFRLLVCLGTLLAGDENSQAIANSLDASVLIKRLVSVSEPAKVGDCARYVNQLL
The following text describes a protein:
Function:
A nucleoid-associated protein (NAP) required for septum formation and normal cell division as well as for DNA segregation. Binds about 135 sites across the chromosome, most of which are genes involved in virulence; most DNA-binding sites are immediately upstream of transcription start sites. When mIHF is depleted most of the genes are down-regulated. Binds supercoiled and linear dsDNA in a concentration-dependent manner, probably non-sequence specifically. Binding compacts DNA, protecting it from degradation. Initial binding to supercoiled DNA opens it fully, followed by bending and compaction. Bends and thus compacts linear DNA. Binds DNA via 2 sites, forms left-handed loops on linear DNA; at low concentrations unwinds larger cosmids (42.6 kb) then collapses and condenses DNA as protein levels rise. Forms mostly left-handed loops on condensing cosmid DNA.
Subcellular Localization:
Cytoplasm.
Domain:
Forms a globular protein with 5 short alpha-helies and an extended N-terminus.
Sequence:
MALPQLTDEQRAAALEKAAAARRARAELKDRLKRGGTNLTQVLKDAESDEVLGKMKVSALLEALPKVGKVKAQEIMTELEIAPTRRLRGLGDRQRKALLEKFGSA
The following text describes a protein:
Function:
Organizes the germ plasm and directs localization of the posterior determinant nanos. Oskar protein is required to keep nanos (nos) RNA and staufen protein at the posterior pole.
Miscellaneous:
MISCELLANEOUS: Capu, spir, and stau are required for the initial localization of osk to the posterior pole.
Subcellular Localization:
Endosome. Note=Colocalizes with endocytosed yl/yolkless on endosomes.
Sequence:
MAAVTSEFPSKPISYTSTNTSAKTYYLKSVKKRVTTCFQQLRDKLQSSGSFRKSSSSCLNQIFVRSDFSACGERFRKIFKSARKTELPELWKVPLVAHELTSRQSSQQLQVVARLFSSTQISTKEITYNSNSNTSENNMTIIESNYISVREEYPDIDSEVRAILLSHAQNGITISSIKSEYRKLTGNPFPLHDNVTDFLLTIPNVTAECSESGKRIFNLKASLKNGHLLDMVLNQKERTSDYSSGAPSLENIPRAPPRYWKNPFKRRALSQLNTSPRTVPKITDEKTKDIATRPVSLHQMANEAAESNWCYQDNWKHLNNFYQQASVNAPKMPVPINIYSPDAPEEPINLAPPGHQPSCRTQSQKTEPTENRHLGIFVHPFNGMNIMKRRHEMTPTPTILTSGTYNDSLLTINSDYDAYLLDFPLMGDDFMLYLARMELKCRFRRHERVLQSGLCVSGLTINGARNRLKRVQLPEGTQIIVNIGSVDIMRGKPLVQIEHDFRLLIKEMHNMRLVPILTNLAPLGNYCHDKVLCDKIYRFNKFIRSECCHLKVIDIHSCLINERGVVRFDCFQASPRQVTGSKEPYLFWNKIGRQRVLQVIETSLEY
The following text describes a protein:
Function:
Binds to the Wnt signaling protein wg, stabilizes it and promotes its extracellular distribution. This is required for establishment of a wg gradient during development to allow for regulation of target genes at different levels.
Subcellular Localization:
Secreted.
Sequence:
MKHSPLIASACLALVLMSSSLIGSTEARNKKKYVGETGGDFEFIDEINKNTQSNKNLGEHKRWIHDPSSDLCRPLNCKKREICLLEDEFSAVCVSKKELHKNRDEIITKAKYLEEEAKRRVNQQDNQDSQDAEDINNDDEDNSSDGGSSNSSPTGTNNAQASVQGNEETDDEDKSLSLGDDDESKEDDVFYENSIAAGDKQQQQQQLSQPAAGPSVIQQDDDEELDNCKPCPVAKPTFLCGADNRTYSSLCRLDYHNCIHSTSIRIACKGFCPCKEIVDGKRLQRISGYNNKYNKKISLDQQQQQQQQQQQQQQQQQAYKDSNNNNIMMNSGNIMGGNNNDFNTIMNDKEDNNRHNNHINAQYTFTPEEIKYDNKHYKYLKYTAYKKDSKYQEDKHKMRNYNEVVEKQQQKFNKNSNLNAYPSKSAECKPQQLTAIGNRLLDWFSVIMADSKKRRQHSQKSKAHFPPACKTEAKWMFGHLDLNNDGQLSLQEMYDLEHDQNERCIKPFIDTCDLDTDSSINTREWCRCFEKTDRPCAAVRRRIAGDFAGAYAPDCDIQGFYKPTQCHNSVGVCWCVDKHGVEFANTRTRGKPNCESVVNNAASLTSDDEDEGADDEDSAEGSADQMLVF
The following text describes a protein:
Function:
Putative Notch ligand involved in the mediation of Notch signaling.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MSHNHYYRIIVVGALLQLIALVSPSGAVRYVPKWKKQACELPTPQNEYSHYVCDDNGDVKCLPGWTGDLCDVPICKKGCDPLQGYCKRPGECRCKLGFYGENCNRCIPLPGCQHGGCQVSFECVCHKGWDGIFCSEPICRSDCHPSRGYCEAPGECRCRLGWAGPTCRDCQVLPGCMHGTCTKPLECKCLPGWTGILCQTPICAANCSREHGYCRRPGECRCKVGWMGQECNKCHPYPGCVNGDCRRPWECNCKPGWGGMLCDEELNYCEQNPDTCQNGGKCKSVIKDDGHYRCECPSGYKGRNCEILPPSMMTSTTSSSTTEQPSTTMMADVSSELSTIGLENLETYRNSSSTGEDYLADEYSSEDLDNEA
The following text describes a protein:
Function:
Escort protein required for sre1 processing at low sterol as well as oxygen levels. May regulate export of the scp1/sre1 complex from the ER at low sterol or oxygen levels. 4-methyl sterols bound to scp1 may mask an ER export signal in scp1 leading to retention of the complex in the ER. Release of 4-methyl sterols may trigger a conformational change in the SSD domain of scp1 unmasking the ER export signal leading to recruitment into COPII-coated vesicles, transport to the Golgi complex, proteolytic cleavage of sre1 in the Golgi, release of the transcription factor fragment of sre1 from the membrane, its import into the nucleus and up-regulation of genes required for ergosterol biosynthesis as well as anaerobic growth (By similarity). Binds 4-methyl sterols.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MRIFTLGKGRISRGYARQVNPSLFAKYSYCIANNPWYFILVFTLLSITGIYSSLVAYQQSLYDQSLARWSAWYAESINAEANVITKQLYLLGTNTSVFSEDYLSNAYRWETSFHQYLAEYGYPCIRDEKSCVTISPIPKYYGKVDPVAQYSYTKGLPENEREVNKLRNDTIAEGFDSLSAFVITYFLKPEQVDTFHVVLKKFISETPNLYASLLDTSPTTVVARIPDLTVIYRWYLWVGFGVGLFAYLYLSLVRLHDIRAKFGLTATIFIQSGTAYFSTCSLLYFFERTGPICPWPMAYYIIIFMDIENSFRLLRAVIASPQTKRVPSRIMEGFSSTIIASFSSLLKKLLTLFVLSFFVYPLVQEFCLFLACSFVVSFLLHGSFFLAVLSVDIRRLELQDFLDSNSSNRNSKWWVPYLEYVRFMWSPWIIDNLGTVSFHMYVIYLQLQSSTDINGSWRLASPNIRFLITLYHRLGRILRERKLFPLITTGWFGDPTFLEALKEKTMAENLVIALYRPVILDTVNRRDYTNVYNSFHDRRVWRWSTFFSILFAIDFAVGLLVKALLRGWSDHDELSTDTTLHEEKFRIEPVPVHHQLDILKIAVSENYKTFASVGLDRCLVVWDLRQWCTKLVLSKEQMPRTLKAIALDPQGNYVSLFSKDTLFILNVESPCLMLQHSYHCKPNSKLNVFWMPGTHKDDEWKNFELVVVESSGEIQVFSLTIEIEGADIALVEKFQLSSPIIKSISIVSPTANRIACLTESGEVTVYSKKGPVWSPKILSQNKNYLTETKKDIYGIAMADILFLARDSGVDMIDLKNDELLHSFTLPPIKVNTFSVGVSNSRFVNGQFRVSSISFCFTHAVTEKVLYYYYGNECNESYIILNKWDQQPNLVDVHDPDNSLACLTFDELQENIHEVEDASECVMSSDGLYIFGMRRKSSSGICPTADEKNEDNGFTLRNRKLRTGHYNWTSYVPLLDSYMQDMEHKKNTHSGGETQVWEVWMYSQSEKKHRCKSLKMYNSLIIADPGPSLAVSDRCVAIVLGNYVALVGYGSEIFRDFYQIRNSDEMDRILRRKRKNLQRKRSGTIGC
The following text describes a protein:
Function:
Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MIKYSNLVIPKTKSILKSGCNNNIGYGDRYFFNKLFGSNDASDTHNQPTTKIVTKEMTKELKYPVNQVYSVIIKVEDYKEFLPFCLNSTILKREKDKNHFEAELEVGQGTIKESYVSKVVYKENKFIESTATDTPLFHKLINTWSFKQGQTPNTTIAHCKLIYQFKSPFYATLMENFFASSLDVMINSFDKRCDELYGSSNSFKK
The following text describes a protein:
Function:
Displays serine protease activity. Seems to have a broad substrate specificity.
Subcellular Localization:
Cytoplasm. Note=Is leaked to the culture medium during the late stationary phase owing to cell lysis.
Sequence:
MFGYSMVQMVRANAHKLDWPLRETVLQLYKPFKWTPCFLHKFFETKLQNRKKMSVIIEFEEGCHETGFQMAGEVLQKEKRSKLKSRFNKINCCSAEVTPSALHSLLSECSNIRKVYLNREVKALLDTATEASHAKEVVRNGQTLTGKGVTVAVVDTGIYPHPDLEGRIIGFADMVNQKTEPYDDNGHGTHCAGDVASSGASSSGQYRGPAPEANLIGVKVLNKQGSGTLADIIEGVEWCIQYNEDNPDEPIDIMSMSLGGDALRYDHEQEDPLVRAVEEAWSAGIVVCVAAGNSGPDSQTIASPGVSEKVITVGALDDNNTASSDDDTVASFSSRGPTVYGKEKPDILAPGVNIISLRSPNSYIDKLQKSSRVGSQYFTMSGTSMATPICAGIAALILQQNPDLTPDEVKELLKNGTDKWKDEDPNIYGAGAVNAENSVPGQ
The following text describes a protein:
Function:
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
Subcellular Localization:
Cytoplasm.
Sequence:
MPITPATATPSSSNGTAEAILLELVDENGVTIGTAEKLSAHQPPGRLHRAFSVFLFDERGRLLIQQRALGKYHSPGVWSNTCCGHPYPGEAPFAAAARRTFEELGVSPSLLAEAGTVRYNHPDPASGLVEQEYNHLFVGLVQAELRPDPEEVAGTAFVSPAELTERHAQDTFSAWFMTVLDAARPAVRELTGTSAGW
The following text describes a protein:
Function:
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
Sequence:
MVLFSQATCWKAYRFKKSRGGLFVRFNSAFSSDRFAQLASRPASIHQIYQSLSTDPYVNLSIEHFLLEKAPPDSSILFLYVNRPCVVIGRNQNPWLETNLQKLHNDREESTKHSDGALLVRRRSGGGAVFHDAGNLNYSVISPRATFTRNKHAEMMMRALHRVGAVNTSVNERHDIVMSESDGQPRKISGSAFKLTRFRGLHHGTCLLDSPNINELGSFLRSPAREYIRAKGVESVRSPVANVSSSMEDAPAGFSMQAVIASVMDEFAQLYNASPDAVRRAQRAHAVEPELYAGDNWVAGAVGDLEADAVPEIKKGMDELKSLEWKYTQTPQFTFSTYPIEEDPRERPALPPSLPPSTRVFLRLKHGAIIESCISTSNDPSLAAEQASRVHEALKGRNLHELQPSQWTEVLVSRLSADEEPVTVQELASFITSKFGS
The following text describes a protein:
Function:
Binds calcium Ca(2+) and may act as a signal mediator to buffer Ca(2+).
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MATVEVEQVTPVAVENVEVPTKTVEETVVETEVTQQPEESVPAVTEQKSEAPIVETNEEVVVEEAEKKDEETEKKTEEKDEKTEVITETPVVEEEEKKAEEVTETPAVVEEEKKTEVVEEKQTEVAAAEEVAVEKAEE
The following text describes a protein:
Function:
Mediates influx of magnesium ions.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MRLRVHRPRWARSRSKIGNVPGDLSSDVSTKKKDTVPSHIRVIQYDGRTHTNEVVESIDNEDSDNPDIVTWIDLHGIRDMEALRSLGRRFGLHPLALEDVVQMDQHAKMERYGETLFFIARMPVGDNGFQTEQVSIFLVGNTVITIQEKVGDCLDPVRDRISRAMGRIRDRGADYLVYAVIDAIIDGYFPIIDRYESHLSEMAELLQDADNDNLPMHLHHIRADLLSIRKTVQQHRDALRLLLREGDGILANDTRLYLRDCQDHIGQLMEAADTDRETCGELRELYFALLGQKNNDVMKVLTIIATLFIPMSFVAGIYGMNFDQKASPLNMPELEWSFGYPFALSVMMVLALSLLYFLYRKGWLW
The following text describes a protein:
Function:
Required for survival of imaginal disk cells possibly by regulation of cell apoptosis. Required for germline stem cell self-renewal through mediation of BMP signaling.
Sequence:
MEDNKELQCLICKYSDTDDLVFGEWMIVRNLQVHYFCLLLSTHLPQRGGDSSGILGFLLRDIREEAAAAEKRKCWYCNKIGASLQCDRCRSLFHLKCGLENRAVFEFCGQYKSYCYKCRPMDDYKRQLQSNPPRNATCPICFSSIYKVELHCVVYGDCCRLGFAHKKCMRQYALTSGYYLRCIWCRSERFRDSIRLQSVFVPDRDATWEKQRNAYRELHERNLKCDQPNCLCPSGRTYNRLSWVILCCSSCAATSAHLKCLVGALRLPKKRERTDFKCSMCLDVERRIAEGPARTTEETNADGDNQVDGSFYVQKLGPDAATRSLTQTPVFSEEDESERSSNITVIFSQPKSNATSERLSLSPPQEEMIVEIPDSPEASPKTSIDENHSPQPIARRDTSDSPQPIAASEIPDSPQPTAASEIPDLPQTTAINVNPELTQQTALNTIPHSPQPEASFSTQLVSQTFDCPQPQEQAVAKAPNSPSLPKEDPNTLLVLKSGFQCPGEPFFYLVIYEFEHGTCMGECIGTCVLRFKEDDPRIQDTSQAALERVNITPDDVWCRSEDRGIFEHIEKFHEWYRSEGFS
The following text describes a protein:
Function:
Structural component of the gap junctions.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Sequence:
MFVFRVLNTVPYTNRTGAKDLVASIHSFLTSNLLVGLAVLISWKQFGGTPIECMVPLDFTSAWVQYSNNYCWAQPTYFIPFTEELVEQVVDPADVVADGITIGNGGNRPRFVKKGGEKISYYQWMSFFLLFEAACFRLPCFIWKYFASQSGMQVGEILRVASDENNAVPLVKKANIDALCIHLRGVLRFQKRLKLKKIVPHKILRFLNIKYSAYYVTFIYFVAKVAFLLNVILQSKLLNKYMLPHDRQQNFGFDMWKTIFYGSTNGNETWRENGVFPRVTLCDFETRDMGNVQMHTVQCVLLLNLFTEKIFVFLWAWYILLTAFTVGNLFSWLFAVFNETYNEHFILNHLEMCETPFDKDDLKNREHVTRFITLYLGTDGLFLLQLIAQHADVVFTTELIAALFKTYIEIEAQRATLKQMNAVLPLLRPNDESQVESGKNTAPSTSHNVRRRGTEQLEKNVKSRQGSLSTQLRPFNSFEEPDQPTKKFDDSSSEDENSKKGSKKPSPTKKKASSKNSPQSSSNSRRPSLAHTASPAFTHHHEPDSKIPKTAEKKHW