lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
Sequence:
MGGGGVKERGENPVPGRCCFFLEKKGRFCRVERVKGGGVWLMFAFAIDSRFCGQHVSDATFVPCPYSGSHQVRADLLERHLRKCNDRPRPPPAWFKQDVNNLAATTTNGPFAPAPLLSEIDAATLQAVAALINVLYDEGQTQLGPITVHSALHPAHNAMLDGTEAYGVTRRHVQQNSSLSRLITDDGVPDQDTSSALPPLVVEFGAGRAHLLHCLRHALGWSSPAAYLALERDTIRLKADRYHRARPEPAVSYSRLRADIANVVLAATVDAQPPDVSTTPASAAPLRPLVACWKHLCGAATDFAIQAIVHYQAAGGVLRHVTGATCCHHRCTWGTYCNRPWLEAHGVTPDTFGIMTRMATMNVTTAQMVELGYRCKRALDYGRALYLRAQLGVPLCLVEYVDQKVTRENVCLTSRQPGAKT
The following text describes a protein:
Function:
Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest. May also cooperate with MYB to activate transcription of the ANPEP gene. Binds to the consensus sequence 5'-CCCG[GT]ATGT-3'.
Miscellaneous:
MISCELLANEOUS: [Isoform 3]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay; MISCELLANEOUS: [Isoform 4]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay; MISCELLANEOUS: [Isoform 5]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Nucleus.
Sequence:
MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQNDPDEVDSEDSTEPPHKRLCLSSEDDQSIDDATPCISVVALPLSENDQSFEVTMTATTEVADDELSEGTVTQIQILQNDQLDEISPLGTEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPVLLENKSGSGVPNSNCNSSVQHVQIRVARLEDNTAISPSPMAALQIPVQITHVSSTDSPAASVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTNPTVTLAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSLSQEELTVDSDLHSSDFPEPPDALEADTFPDEIPRPKMTIQPSFNNAHVSKFSDQNSTELMNSVMVRTEEEIADTDLKQEEPPSDLASAYVTEDLESPTIVHQVHQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPIFQHHQEASNIIGSSLGSPVSEDSKDVEDLVNCH
The following text describes a protein:
Function:
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.
Domain:
The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
Sequence:
MSSSDYYSQRVGDTVFTVQKRYTNLTNIGSGAQGVVCSAFDTVTQEKIAIKKLVKPFQNETYAKRAFRELRLMKMVDHKNIIGLKNLFTPAKSLDDFQDVYIVMELMDANLCRVIGIELDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARTADQTFNMTPYVVTRYYRAPEVIVGMKYKENVDIWSVGCIFAEMIRGDILLPGKDYIDQWNKVTQVLGTPPSVFFKQLSSSVRLYCESQPRYAGKSWKDLFPDDVFPNDTPEDKAKTRHGRDLLSKMLQIDPQNRITVEQALAHPYVSIWYDPAEVHAPPPKRYDHALDEQSIPLDQWKTRIYEEVKTYNS
The following text describes a protein:
Function:
Copper-sensing transcription factor that regulates copper uptake by transactivation of Ctr3, a high affinity copper permease. Binds to the palindromic UAS sequence 5'-TGTTGCTCANNNNAGAGCAACT-3'. Also transactivates Sod2, a mitochondrial manganese superoxide dismutase through the palindromic UAS sequence 5'-GTTTGCTCA-3' with 352 bp separating the two inverted repeats. Loss of function indirectly leads to rearrangement of mitochondrial DNA associated with senescence in wild-type strains.
Subcellular Localization:
Nucleus.
Sequence:
MPIINGQKMACGPCIRGHRSTKCNHYNERVMVPVRKPGRPLSTCPCPPGKPCVCGGVRVAIPKKQKCHCPAGTVDSATSSEFDPSPVDTPISPASRTSSNRVTKSGSGSKSASRRQSLALANLERMDPNSINLIPSPNGNGMIGITAMVSPRDATFGHPMGMVPMGPRESFVPAPPPDFGGPMGYNMPPSMPPHMPPPHYPPHIQIPQHIKTENGGFVPMLNGTFVSPVPIPAFVDGPHPQGMQAFNGPPPPPPSNPVLEPSAMSKPKGGSGGGGCCGGGKKAPQIQAPPPVPAPLPTPPQQQMPNIMPPPQPQNAPSGGGGSCCSSKSSQPPPMPQMSPNAMQAPPQPGFGQGFMPQYQTPIDIKMENMHHHQPFQFPGQTVFTYPAEYGSWQMPINPAIWQQVVSRPPTQQQHETPISATAPNGNNGTVGGNSHECGCGEGCQCVGCLAHPFNSQMLQYVQNAYSPNSSHGNSGSADSSANASPSANPLNLASPVEIPSGPELPPSHQTQPQPPPRPNANESDGSSNAPTPPNEGSPALSNEEELTALDYYFVHLPISALCGGALDMCPCDESCECVGCLVHNTAGFPQGDGGFS
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MKKLLQWCSCFYLALWIGITQLGLMANGKLHASGKWYSNNKKFPYVSVLVDQSGHGNFSTVQSAIDSVPSNNKNWICIYIKAGIYREKVKIPYDRPYIILKGEAKRRTQIIWDDHDSTAQSPTFMSLADNIIVKSIRFVNSYNFLNSNNPRVPAVAAMIAGDKSAFYRCGFAGVQDTLWDDQGRHYFKKCTIQGAVDFIFGSGQSIYEGCAIQVIGDGFITAQGRTNPSDANGFVFKRCNVFGRGSAYLGRPWRGYSRVLFYQSNFTNVIHPEGWNAWDFVHHENQITFAEYGNFGPGADTKNRVSWAKKLSHQTLCKLVSMSFIDTENWIQDQPL
The following text describes a protein:
Function:
Completely dephosphorylates 'Ser-2', and partially 'Ser-5' and 'Ser-7' of the heptad repeats YSPTSPS in the C-terminal domain (CTD) of the largest RNA polymerase II subunit (RPB1). Involved in defense response. Acts as a negative regulator of immune gene expression and immunity to pathogen infections. Preferentially dephosphorylates 'Ser-2' of RNA polymerase II CTD. This counterregulates the MAP kinase (MAPK) or cyclin-dependent kinase C (CDKC)-mediated phosphorylation of CTD in response to pathogens and upon perception of microbe-associated molecular patterns (MAMPs). MAPKs phosphorylate and activate CDKCs, which are CTD kinases that positively regulate plant innate immunity. Acts as a negative regulator of stress gene transcription involved in abscisic acid (ABA) mediated signaling pathway and cold resistance. Acts as a post-transcriptional gene silencing (PTGS) suppressor.
Subcellular Localization:
Nucleus.
Domain:
The BRCT domain is required for interaction with RAP74.
Sequence:
MLVARSGCSRTLIRMGNDENLMVMVDVEEGEIPDSVNTEIEVKHKSTTTTADVGGDVDVGVVAGGRGGGGGGSNGNSRVWTMEELISQYPAYRPYANSGLSNLAWARAVQNKPFNEGLVMDYEPRESDKIVIEDSDDEKEEGELEEGEIDLVDNASDDNLVEKDTESVVLISADKVEDDRILKERDLEKKVKLIRGVLESTSLVEAQTGFEGVCSRILGALESLRELVSDNDDFPKRDTLVQLSFASLQTINYVFCSMNNISKERNKETMSRLLTLVNDHFSQFLSFNQKNEIETMNQDLSRSAIAVFAGTSSEENVNQMTQPSNGDSFLAKKLTSESTHRGAAYLRSRLPMLPLLDLHKDHDADSLPSPTRETTPSLPVNGRHTMVRPGFPVGRESQTTEGAKVYSYESDARKAVSTYQQKFGLNSVFKTDDLPSPTPSGEPNDGNGDVGGEVSSSVVKSSNPGSHLIYGQDVPLPSNFNSRSMPVANSVSSTVPPHHLSIHAISAPTASDQTVKPSAKSRDPRLRLAKPDAANVTIYSYSSGDARNLSKVELSADLVNPRKQKAADEFLIDGPAWKRQKSDTDAPKAAGTGGWLEDTESSGLLKLESKPRLIENGVTSMTSSVMPTSAVSVSQKVRTASTDTASLQSLLKDIAVNPTMLLNLLKMGERQKVPEKAIQKPMDPRRAAQLPGSSVQPGVSTPLSIPASNALAANSLNSGVLQDSSQNAPAAESGSIRMKPRDPRRILHGSTLQRTDSSMEKQTKVNDPSTLGTLTMKGKAEDLETPPQLDPRQNISQNGTSKMKISGELLSGKTPDFSTQFTKNLKSIADMVVVSQQLGNPPASMHSVQLKTERDVKHNPSNPNAQDEDVSVSAASVTAAAGPTRSMNSWGDVEHLFEGYDDIQRVAIQRERVRRLEEQNKMFASQKLSLVLDIDHTLLNSAKFNEVESRHEEILRKKEEQDREKPYRHLFRFLHMGMWTKLRPGIWNFLEKASKLYELHLYTMGNKLYATEMAKLLDPKGVLFNGRVISKGDDGDPLDGDERVPKSKDLEGVMGMESSVVIIDDSVRVWPQHKMNLIAVERYLYFPCSRRQFGLLGPSLLELDRDEVPEEGTLASSLAVIEKIHQNFFSHTSLDEVDVRNILASEQRKILAGCRIVFSRIIPVGEAKPHLHPLWQTAEQFGAVCTTQVDEHVTHVVTNSLGTDKVNWALTRGRFVVHPGWVEASAFLYQRANENLYAINP
The following text describes a protein:
Function:
Component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay (By similarity). In contrast to orthologs, does not possess decapping activity and does not remove the 7-methyl guanine cap structure from mRNA molecules. In the nervous system, negatively regulates the expression of insulin-like peptide ins-7, which in turn promotes longevity. This may in part be through promoting the activity of daf-16 in distal tissues. Required for the developmental axon guidance and regrowth of PLM touch receptor neurons. In ADL sensory neurons, plays a role in ciliary shape formation. Acts in neurons to promote larval survival at high temperatures by negatively regulating lin-14 expression (Probable).
Subcellular Localization:
Cytoplasm. Cytoplasmic granule. Note=Diffusely localized in the cytoplasm, but accumulates in puncta during pronuclear migration in embryos. After pronuclear migration, accumulates in P-granules which segregated to the posterior cell, and smaller puncta scattered in the cytoplasm. Localizes to cytoplasmic puncta in neuronal cell bodies of neurons such as touch receptor neurons. In some cytoplasmic puncta in touch receptor neurons, co-localizes with car-1.
Sequence:
MSDAKKKAAAELAAKNLAQLQKIDIAASKILDKMPFAAIYHIDAARKEWNQSNCEGTFFVYQRADRPYFSFLIANRNDPSDFIEPLTLNHILRHDGNFIYFYKDLASIQALWFHQIDDAQKIYNLLQKLVNRLKGSTTEQARAAKAASEAPQASVPAPTQAPAAPAQAPQMAPQAPPKVDLLQLIKSAQNPPQKSAATIEQMPPMLQKLMLKEPGAAMSADELEKDLIKSAKPHRNHLLQEFTNSTSAISLAAVSTKPLHGSEGDVESDIAEGEILEPLDASFVVGSGEQTPVLNKEQFISAIAHLMQTDDEFVSQIHQAYVSALNRRLNID
The following text describes a protein:
Function:
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
Sequence:
MRTFTWRKGSLSKVNTCYVLAGGKSKRFGEDKLLYEIKGKKVIERVYETAKSVFKEVYIVAKDREKFSFLNAPVVLDEFEESASIIGLYTALKHAKEENVFVLSGDLPLMKKETVLYVLENFKEPVSVAKTEKLHTLVGVYSKKLLEKIEERIKKGDYRIWALLKDVGYNEVEIPEELRYTLLNMNTKEDLKRILAIENHY
The following text describes a protein:
Function:
Vesicle trafficking protein that functions in the secretory pathway.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Prevacuolar compartment membrane; Single-pass type IV membrane protein.
Sequence:
MAAPGDSWVREYNEAVKLADDITNMISERSSLPATGPEAQRHSSAIRRKITILGTRLDSLQSLFSKLPGKQSLSEKEMNRRRDMVANLRSKVTQMASALNMSNFAIRDSLLGPEIKQADAMSRATGLDNHGVVGLQRQIMKEQDEGLERLEETVLSTKHIALAVNEELDLHTRLIDNLDEHVEVTDSRLQRVQRKLAILNKRTKGGCSCMCLLISVIGIILLVAVIYMLIKYL
The following text describes a protein:
Function:
Dephosphorylating regulator for many key proteins. Has an important role in osmotic stability and cell shape control. It may negatively regulate the osmosensing signal transmitted through wis1 map kinase.
Sequence:
MGQTLSEPVTEKHSDAGGDARLIYGLSNMQGWRISMEDSHCAIVDMVPESNEHNISFFGVYDGHGGDRVAKYCRQHMADIIKQQKSFWKGGFEEALKSGFLAVDEAILRDRDMQDDPSGCTATVAMIVDNLIYCANAGDSRTVIGSRGIAHPMSFDHKPNADAEKARIAAAGGFVDFGRVNGSLALSRAIGDFEYKKNADLPPEKQIVTAFPDVTTRLISEDDEFLVLACDGIWDCKSSQQVVEFVRRGIASHQPLATIAGNLMDRCIASNSESCGIGCDNMTVCIVGILNGMTVDQWYDTVARRVAANDGPCAPPSYAELRGPNTIADARNLELEYDHFANHEYGSGDTYEDSSDEETRTITQSYYPH
The following text describes a protein:
Function:
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
Sequence:
MNFKKLPKIELHCHLDGSLRIDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIAFELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLAGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGAKFIGKGVVAIDLCAGEEPHFPGKYIEVLKLAKECGYRITIHAGEAGVGENVLEAINLLNAERIGHGIYIKNCAEAYKLVKEKNIPLEVCPTSNLHTKAFESYETHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIEDYKILYLNAVEASFASPETKEILKSYANEITA
The following text describes a protein:
Function:
Possesses 3'->5' exoribonuclease activity in digestion of DNA and RNA. Cleaves nucleic acid substrates with efficiencies in the following order: single-stranded RNA (ssRNA) > double-stranded DNA (dsDNA) > single-stranded DNA (ssDNA). Involved in apoptotic DNA degradation.
Sequence:
MAYQHCPFDTLLILDFETTSDAANQDYPCEVIQFAIVAYDVPNDKIREDISFNKYVKPVLNRTLTKNCVDFTGIPQRSIDTADTFDVVYEQFQQWLITLGLEEGKFAFVCDSRQDLWRIAQYQMKLSNIQMPAFFRQYINLYKIFTNEMDRMGPKELSATTNIGKMNEYYDLPTIGRAHDAMDDCLNIATILQRMINMGAKVTVNELLTCCASWRRQPLVYNKEWRSSFMDAGKIFERVLPLVVTTIRAGDFRLEMYGVCRYCRKGMDVCGTSHQQTPHDLYKNEEDPIHFAKIAGYY
The following text describes a protein:
Function:
Potential Ras effector protein. May function as a guanine nucleotide exchange (GEF), by exchanging bound GDP for free GTP (By similarity).
Sequence:
MVNAVMDAIALLSSLASDLDIMLNDLRSAPSHAATATATATTTATVATATATTTANRQQQHHNHHNQQQMQSRQLHAHHWQSINNNKNNNISNKNNNNNNNNNNNINNNNNNNNHSAHPPCLIDIKLKSSRSAATKITHTTTANQLQQQQRRRVAPKPLPRPPRRTRPTGQKEVGPSEEDGDTDASDLANMTSPLSASAAATRINGLSPEVKKVQRLPLWNARNGNGSTTTHCHPTGVSVQRRLPIQSHQQRILNQRFHHQRMHHGTSEPIPSGVATPSSLDSASVDGGKSHTGNNNNINNNHNGQQSQKSQQQAGLAAKLNVLAQSNLNNNNTTNQPGSMTPASNRTGLDSNQNQKQNLNADSRRSSSVDPDADADDVVDAAHGGAFEDDMQALLPKCSRRSRDELSQSRTSLVSSSEGGILAEGETSSEDDEEEPVEAEDEGEESSRDSSDNSPPCDLGLMERLLVTHPMWFLPGIQRSGAVHLLQGKEEGTFIVRGSSQPNTMAVSVRLPQDTGPYIEHYLIQSHDNVLSLESSRFTFGSIPSLIAHYAQCCDELPVQLMLPRVLREANNRKKLSSLALLGQEFWSYVSSPALLGPLTPSVAPSKDQQLLDAKSPLSLTETSGLGTATFFSDTVSKPPPTGAPPLPGGGLFSPTGSGQLLGFFSQAGTPSDTTNSSLSSFTTSGGQHMQLLSPNSVDSVILTMSPVDNPGHYLPGSTGAPMAPLCPSVVDQQLSTFKVAQTAPEVDQVRPQRPKPPNTLNLKPPAPPLRWSKPHSPDQNGSANGNFTVTTTVTFSMENGGGGGSGPTVGNGNGKFVEVTTPAASNPFNALLNGQASTFQTFAKRLSPEGECKDTLSSQGSSSNDSRWPPPARKLLTSPMTPLTPSGGSSSSGGKSRKSRAGKESQHYKESDILESPPMQYCASALSDKISDYEDVWSHDPSDRASLLTSFRPALDTVGGVMNRRPDLLAETPSTPTPTQQSHLTPCEEETTATPNESSSQSLLQFSGDVPARSRAGLLLPNLSGQVPPVAMTKSMTAAEDDGGDTTPTAEGQANGASRSKQGSPFYAEPADALRQAGLTSAATAILRRQHRSQMLHASQRHSEPLKAGFGGSGNGAMLQPSDLEKLAGSLDELKPKPKVSQQQQQSQQQQQPTKRARNRIDHWQLDSSWEFMAKQDTGSHAGGDYDTAAIDWQEKENSLGRDSRADGQGKKRTLTIHQIIANRLPDLNLPELVRCSTPPQTAALQPHVLGQDKAGVGCDGSQKSFQSQIGCRLSSYDNVFCQNSFGGIDSAQSDDGTIFSEPWDSSQWDTFLPHDDATINSDTIHLSKCRPALSEDDTIVEELQSTKDGSNGSCNQDTLKANRNGAGHHKLNNGNGNGKANNRPKVATILRNPSMRDREVLCHPRNKMSIQSSGPGDSLRAYTLQLAQDPSSTFARNIENFICCTKESREAAPQVVMRNMRQFMSGMKNYLVKHGEGKFHAELETARARLKSDEFLNLDAMLETVMHQLVVLPLREHLYGIFVDHYQRSEDIQLLAQNVRYACEREAADFGIRPTVTPPSQAALRLIANLLWRLQEAELPLDKLELFLCVISTVFDATGCPRGQQLGADDFLPVLVYVVAKCGFVGAEIEAEFMWGLLQPTLLNGEPGYYLTALCSAVQVLKTFMASEGESGSGSLDWRSSCLPACSSVLRVIIPDECNGSLQTRTLPVRPHTTTREVCRIIAHKARITNPQDYALFKLVDGEETLLTDAECPQDARLAAKGKHCMLAYKRIDAKIAWPTAQLAGH
The following text describes a protein:
Function:
Together with zig-5, required postembryonically to maintain the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP and HSN neurons by preventing their displacement that could occur during body growth and movement. May act by reducing L1CAM-like protein sax-7 (long isoform) adhesion.
Subcellular Localization:
Secreted.
Sequence:
MRRFSNICVILFSFLYATGHGASEEVMACLRQERSRVENPSQTIVNVVAENPAYLHCSVPPDAEHEIAWTRVSDGALLTAGNRTFTRDPRWQVSKKSANIWVLNLRRAEQQDSGCYLCEINDKHNTVYAVYLKVLEPPLPSPSSLQKKSTKLMANMSGDEVVLNCTVTSTDKDEEVLDVVWTRDGNTINFNDTEKYILKVKRDAGVVIETMRIRKATMEDDGNYACEHSQQKASQIVHINKAEAQTSNSATFPCSIFSISIFMYFLYL
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MEDNDYSFGGMEDSSSRVSYDQGSEENGQGGDSSIVMEGGFSESQLGGGDSNSGLGVIAAKADFEWSAARETTEVKKGELNGNQTAEDSGEDDESKNRKRPFIDEMGEEDSESLTEKRVKTEPKDEVKDETSMSNSESVVEGIREDVSDNESTESLWTAFDVIKPRIMKSEQLPDLEKFWRPVIESPKDFQAWTSLLQYVDHENDVAAAREAYDSFLRRYPYCYGYWKKWADYEKKKAMKKDCEKVFERGLAAIPLSVDLWLHYLNYCRVHHAANETFVREQFERAMTVCGLEFRSDRLWELYINWEVERDDLRRVFQIYDKLLAVPTQFHSTHWENFQDLVNQNDPKELLTPEEYEELKLEIFTERKISTEAVADIKLTEEEIQAIRKKTKERRQVFHSKTEKDITDRWAFEEGIKRPYFHVKPLERGQLKNWKAYLEFEIEHGQQLRIDTLFERCLIACALYDEYWLLYAQHLESRWNDELDNRPLIEKQLRSVYRRACTVHVYDKTTLYLMWSNFEEKTGHLHRAGLILDLLEKVAPKFDSLAVRRVNLARRQGDHSRVISYYRKYIESAKKDNGTLAPLSLRASRFAAKVMGDEELAEEFVEKALEKEPRNARLYIQLFDVRFQKKPLDVEGCVQALNRALKSKLDLEQRCRFAHRKVEFLEDFGMNVDEISTAQDEYQKLAQKLQNDRQAKAAAQMAQQQASATNASTDASAGDDATKTSKTETSATTTSTYSGSYDGATYQGFQGQAGYQGQYQYPGWGGYQYPAGAAAGGWGQQGYYPQQGYGQQQ
The following text describes a protein:
Function:
Involved in the biosynthesis of the antibiotic D-cycloserine (DCS), a cyclic structural analog of D-alanine, used as an antitubercular agent. Catalyzes the addition of hydroxyurea on O-acetyl-L-serine (OAS) to yield O-ureido-L-serine. It prefers sulfide as the second substrate, followed by hydroxyurea, L-homocysteine, and thiosulfate.
Sequence:
MPLFNSILDTIGRTPIVRLQRMAPEHTSVYVKVESFNPGGSVKDRLALSVVLDAEAKGLLKPGDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLVLFPGHLGSKGGNLIADELAEKYGWFRARQFDNPANPSYHRETTASEILADFAGKRLDHFVTGFGTTGTLTGVGQMLRVARPEVRVVALEPSNAAMLARGEWSPHQIQGLAPNFVPGVLDRSVIDDLVTMDEVTARDTSRRLAAEEGIFAGISAGATVATALSIAEHAPEGTVLLAMLPDTGERYLSTFLFDGVDEGSDDAWLASLDTGSGL
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system.
Sequence:
MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKDIDV
The following text describes a protein:
Function:
S-bacillithiolation is the formation of mixed disulfide bonds between protein thiols and the general thiol reductant bacillithiol (BSH) under oxidative stress. BSH is an equivalent of glutathione (GSH) in Firmicutes. This protein is a monothiol bacilliredoxin, which debacillithiolates (removes BSH) the S-bacillithiolated glyceraldehyde-3-phosphate dehydrogenases (GAPDHs) GapA and GapB in vivo and probably a number of other oxidized cytosolic proteins. Debacillithiolates the S-bacillithiolated Bdr (Bdr-SSB) and BrxB (BrxB-SSB) in vitro. Involved in maintaining redox homeostasis in response to disulfide stress conditions.
Sequence:
MAKQLIQSEEEFKRIAEQEGVFVFLKHSTTCPISQAAFHEFDAFANQHEDVPAYYLQVQEARPLSNFIAETYGVKHESPQIFIIQNGEVKWHTSHSQITEAAIEQHLS
The following text describes a protein:
Function:
Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.
Subcellular Localization:
Secreted.
Sequence:
MHISVILFCALWSAVSAENSDDYELMYVNLDNEIDNGLHPTEDPTPCDCSRENSEWDKLFTMLENSQMREGMLLQATDVMLRGELQKLQAELGRLEGSLQKLCGPEAPSETRLARALDDLLQASRDAGRRLARLEDAGALRPQEEAGRALGAVLEELRRTRADLRAVQGWAASRWLPAGCETAILFPMRSKKIFASVHPVTPMKLETFSACIWVKATEVLNKTVLFSYGTKRNPYEIQLYLSYRSIMLVVGGEENRLVADAVISLGTWTHLCSTWDSKKGHMALWVNGDSVATAVDMATGHVVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWEGVLSNEEIREAGGAESCHIRGNVVGWGVTEIQPHGGAQYVY
The following text describes a protein:
Function:
Magnesium transporter that may mediate the influx of magnesium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MGRRSGGRKLPFFSAASTSSSTKRTRSARRLPSLPKPSSPPPPSPTTPPPAPQTTTSPPAPSPGGGAAVAAKVGKKKAGARLWMRLDRWGSSEILELDKASIIRRAGVPPRDLRILGPVFSHSSSILAREKAMVINLEFIRAIVTAEEVLLLDPLMQEVLPFVDQLRQHLPLRSLVGGNGEHSGDGNGAKQDGSPGDQVPCLNEATGAEHELPFEFQVLEVGLEAVCSTLDSSVADLERRAIPVLDELTKNVSTKNLERVRSLKSDLTRLLARVQKVRDEIEHLLDDNEDMAHLYLTRKQAQNQQVEAIMTSAASNSIVPAGASLPRLNSSFRRSVSIATSIYLDNDVEDLEMLLEAYFMQLDGIRNRILSVREYIDDTEDYVNIQLDNQRNELIQLQLTLTIASFGIAVNTFIAGAFAMNIPCHFYDITDGSFFWPFVGGTSSGCFVISVVLLGYAWWKKLLGP
The following text describes a protein:
Function:
Catalyzes the pyridoxal-dependent decarboxylation of aspartate to produce beta-alanine. Has weak activity with glutamate.
Sequence:
MVTDNKTADASFESLLRIFTVPEAPDSTLGIIEKELSQNLNQFLREHIVAEEKPLTEIEKDFTDSSMPESPTYVSEHTEHLLDTLVSQSVHTSAPSFIGHMTSALPYFLMPLSKIMIALNQNLVKIETSKAFTPLERQVLGMLHRLIFGQKDSFYQHWMHSADHSLGAFCSGGTIANITALWVARNRLLKPEGDFEGIAKQGLFAALMHYKCNGLAIFVSERGHYSLKKAADVLGIGQDGVIAVKTDNNNRVCLDDLELKIAQAKAKNIKPLAIVGVAGTTETGSIDPLRELANVAQREGCHFHVDAAWGGATLMSNTYRHLLDGIDLADSVTIDAHKQLYVPMGAGMVIFKDPELMSSIQHHAEYILRKGSKDLGRHTLEGSRSGMAMLLYSCFNVISRPGYELLINQSIEKAHYFADLIQQQDDFELITEPELCLLTYRYVPSNVKAALAIATDEQKIEIYEHLDNLTKYIQKTQRETGKSFVSRTRLTPEAYQHQPTIVFRVVLANPLTTKEILQNVLIEQREIASSSEISLPLLNQIVGNILH
The following text describes a protein:
Function:
Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.
Subcellular Localization:
Secreted.
Sequence:
MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV
The following text describes a protein:
Function:
Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPISYCVSAKKASVVTESVVGNFTGQDNVDLIVARGNRIDVQLVTPEGLKNICEIPIYGQVSTISLIKFRREKQHSLVVVTDKFNLAVLGYRDGKVITRAAGSIAEYSGRSADTAVAMTIHRSGLIAIIGYEGSVKMVHWEPGADVRHFNVRFDYPNVSDFKFVDTGDDDTVRVAFIYDDDHGKHLQFSDLNMHDKEFHTFSKQSCIAADSQVLIPVPAPVGGVIVLGANSALYKASDVNGDVVPYSCSLLKNTIFTCHGIVDASGDRFLLADTDGRLLMLLLNIGEGRSGTTVKEMRIEYLGETSVADSVNYVDNGVVFVGSRLGDSQLIRLMTAPNGGSYSVVLETYTNTGPIRDMVLVESDGQPQLVTCSGADKDGSLRVIRNGIGIEELASVDLAKVIGMFPIRLRSTTDNFVIVSLPDETHVLKITGEELEDVQLLEIETERTTMYASSLFGPDDSELILQVTEEEIRFMSFQKQVKIWRPTNGESVSKVSVNAIHGQIVVAARDTVYYLKCMVDEAGALDIQIVAERKFEAEIACLDISNEGDDYKKPGTFMVLALWGSFSMEVVQLSDLKTACQTNLPSKIVPRSIVATCIEDVHYLLVAFGDGALIYYVFDIKTGTHGEAKKSSVGTRPPSLHRVRNKNRQHLFVCSDRPVIIFSANKKLVFSNVNVKVVNTVCSLSSTSYRDCLVISDGNSMVFGTVDDIQKIHIRSIPMGESVMRIAYQKSTGTYGVCSSRSETKPERVYASKNALANSQSRAKIVATRNEVNDGPPASTSSFMILDQNTFQVLHAHEFGPFEAAVSCISGQFSDDARQYYIVGTGLIYPDESDTKLGRIIVFEVDDVERTKLRRVHELVVRGSPLALRILNGKLVAAINSSVRLFEWTADKVLRLECSNFNHIVALDLKVMNEEVAVADLMRSVSLLSYRMMEGNFEEVAKDWNSEWMVTCEFITAESILGGEAHLNMFTVEVDKSRPITDDGRYVLEPTGYWYLGELPKVMVRASLVVQPEDSTIEYSHPIMFGTNQGTIGMLVQIDDKWKKFLVSIEKAISDSVKNCMQIEHSTYRSFIFQKRIEPPSGFIDGDLVESILDMDRSVAIDILKKVSDKGWDASLPRDPVEMLKVIEDLARMH
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Cytoplasm.
Sequence:
MYPKIVARCMIVITKNRESERNVLICYRNVTNVYFSLRILLNRQNEGNNCKYKLVFSLYRVSFRRMRLNDRQLSCVESVTNGIGLLCLKQADQVCLFTPTVDSHL
The following text describes a protein:
Function:
ATP-dependent DNA helicase involved in DNA repair at least for UV-induced lesions. The polarity of the helicase activity was determined to be 3' to 5'.
Miscellaneous:
MISCELLANEOUS: Present with 5190 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSSNNDLWLHLVSQLNTQQRAAALFDYTRGLQVIAGPGTGKTKVLTSRVAYLILHHHIHPRDIIVTTFTNKAANEMKERLQEMLRGAGVNISELLIGTFHSICLKILYRFGHLVDLQKDWRIIDEKEIDVILDDMIEKVPDQIRDYASSITRKVNLCMPSKNGDEWTIHPKLIKKQISKLKSNAILPEEYILDSNHDAALGYFYQIYQSELSKKNTLDFDDLLMYTFRLLTRVRVLSNIKHVLVDEFQDTNGIQLDLMFLFAKGNHHLSRGMTIVGDPDQSIYAFRNALAHNFLEMGRKCPIEYSTIILVENYRSSQKILNTSEILITQQNKGRQNRAPLRAQFDLDFPPVYMNFPAYFLEAPSLVRELLYLKALPNLFTFNDFAILVRQRRQIKRIESALIEHRIPYKIIRGHSFWDSKETRAMLNLLKLIFSPNDKHAILASLLYPARGLGPATGEKIKNALDTLATDVSCFQILKDISSKKIMLDIPTKGRSVIADFISMIENCQLLLQSTLLGGLSDLFDKLYELSGLKYEYLYKDGKKKNDQLEKSEPNLLNARHKNIELLKNYFLALLSKSESSDKEKNEAIKAATDEAEPIENKVITPKEYLRNFFNSLSLHSDAAEEEESESNKDAKIKREKNGFVTISTIHGAKGLEWPVVFIPGCEEGIIPCVFNDDKKDESEEDEEEDQENSKKDASPKKTRVLSVEDSIDEERRMFFVAQTRAKYLLYLSNTVTVEDVDRPRIASRFLTTDLIKAMSDSQKLFESTNSIKKLYRILNKKPPAEDDKLFSLDQLRKDYNQFIENRRERMIWQGIQMNDVYGIQLSRNKLLGSVSDFTSAADQLRLETQNSIFPQKKLIEKSRPSKINGNYAPKSRVKSPEKRYAPETTSFHSPTKKKVYAPQYVSTTNVPSRQEFHSSTGKNIPFLRREDRSITDISPRSSTRSLKGASPNKTSHMSDDLMRPSPTRKDKVTRNIHFATAGTFRIETQSNVDELHPPEYSNKSGQSLTSSEFSGFSSACSNSDQPTNLIEDINNELDLSDEELLNDISIERRRELLGSKKTKKIKPKTRNRKSKRGDKVKVEEVIDLKSEFEEDDSRNTTAAELLHNPDDTTVDNRPIISNAKFLADAAMKKTQKFSKKVKNEPASSQMDIFSQLSRAKKKSKLNNGEIIVID
The following text describes a protein:
Function:
Involved in pre-mRNA splicing. Involved in the determination of flowering time probably via the modulation of flowering associated genes (e.g. FLC, FT and SOC1) expression.
Subcellular Localization:
Nucleus.
Sequence:
MGDSEAMVSEGYTSAPYGDYNASAATVESTGQETAPIVDASHSVNNDSLVNGTAPVENGSATDNVAVTAPAAEHGDNTGSTLSTEEERLWNIVRANSLEFNAWTALIDETERIAQDNIAKIRKVYDAFLAEFPLCYGYWKKFADHEARVGAMDKVVEVYERAVLGVTYSVDIWLHYCTFAINTYGDPETIRRLFERALVYVGTDFLSSPLWDKYIEYEYMQQDWSRVALIYTRILENPIQNLDRYFSSFKELAETRPLSELRSAEESAAAAVAVAGDASESAASESGEKADEGRSQVDGSTEQSPKLESASSTEPEELKKYVGIREAMYIKSKEFESKIIGYEMAIRRPYFHVRPLNVAELENWHNYLDFIERDGDFNKVVKLYERCVVTCANYPEYWIRYVTNMEASGSADLAENALARATQVFVKKQPEIHLFAARLKEQNGDIAGARAAYQLVHSEISPGLLEAVIKHANMEYRLGNLDDAFSLYEQVIAVEKGKEHSTILPLLYAQYSRFSYLVSRDAEKARRIIVEALDHVQPSKPLMEALIHFEAIQPPPREIDYLEPLVEKVIKPDADAQNIASSTEREELSLIYIEFLGIFGDVKSIKKAEDQHVKLFYPHRSTSELKKRSADDFLASDRTKMAKTYNGTPPAQPVSNAYPNAQAQWSGGYAAQPQTWPPAQAAPAQPQQWNPAYGQQAAYGAYGGYPAGYTAPQAPTPVPQAAAYGAYPAQTYPTQSYAPPVAAAAPAAAPVQQPAAAVAPQAYYNTYY