lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Exonuclease required for organelle DNA degradation during pollen development. Plays non-essential roles in maternal inheritance. May be part of the DNA salvage machinery.
Miscellaneous:
MISCELLANEOUS: DPD1 homologs are present in flowering plants but not in moss, green algae and animals.
Subcellular Localization:
Plastid, chloroplast. Mitochondrion.
Sequence:
MCISISQVSRLRIHSFGSSCCERVHGWIKNSSSLKLLDVRASSVDGKARWIRRNVSTTTQGSRSNTKSSVLGGTVPVTRIIDEESRTKVQPFGNLQQRLAQDKDLSKLLTVIVSDLETTGLHRKNERIIEIAAQDIAGGGYSTFQTLVNPGVVPITNAHIHGIRNDMVCRPEVPRMEELIPIFLRYVESRQKPGGYVMLVAHNGKSFDFQFLINEFNRCSYEIPHNWLLLDSLPLARENMKSVEPTVKLSSSLEALADYYSLTREGDAHRALSDVLLLSKVFQKLTIDLKLSLSDLVLRCHTASDISAAMAKNKKA
The following text describes a protein:
Function:
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
Sequence:
MADKTAEKALKYLSDPTVLAGLGAVAVGSLLYMATRPSESACPVNPHKQSIEIPGDNYARRSAMSEELTAYMFEDCRTTHEVFLRGARISGDKPCLGHRVTEGGPYEWLTYNEVLNRASNVGSGLQELGSNDVEGDTFIGVYASNKIEWVLIEQACAMHAKVITPLYDTLGPDACAFIINQAKMSMVVCDAAKIPLLLQRADQCPTLKFIIKINPDVTSEEKQEGERNGIKIISFSDVEAMGKAHPYEKKLPKPDDLAVVCYTSGTTGNPKGAMITHSNAVAMLAGLCVMIKKCGIRVDNDDVHISYLPLAHMYERLAQLMIFMYGGKVGFFGGNIRKIMEDLQELKPTVFISVPRVLNRVYDKVMKEISSSSIKKFVFNTALSFKKAEVERNIVRKNSIWDYLVFNKIQVLEGYGQTETTAAATIQLVGDHTFGHVGPPMPCTKIKLVDVPDMNYFAKDGKGEICFYGPNVFKGYLHDPEKTREAIDEDGWLHSGDVGEWTENGTLKLIDRKKHIFKLAQGEYIAPEKIEAVYMQCPLVHQVFVYGDSRKSCIVGVVVPEETALKKWTEKNEVQGDMEALCNNEKVRKAILEEMSAMGKKEKLFSFQQVKDIYLHPDPFTVDNGLLTPTLKFKRPVIQAHFKDTFEKLYDSIKE
The following text describes a protein:
Function:
Transcription factor that binds to DNA at the consensus sequence 5'-ACCAAAG-3' (By similarity). Acts as a transcriptional activator (By similarity). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Involved in the differentiation of naive CD4-positive T-cells into peripherally induced regulatory T (pT reg) cells under inflammatory conditions (By similarity). Binds to the promoter region of the FOXP3 gene and promotes its transcription, and might thereby contribute to pT reg cell differentiation in the spleen and lymph nodes during inflammation (By similarity). Plays a redundant role with SOX4 and SOX11 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MVQQRGARAKRDGGPPPPGPGPAEEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLPGRGGRRAAGGPLGGGAAAPEDDDEDDDEELLEVRLVETPGRELWRMVPAGRAARGQAERAQGPSGEGAAAAAAASPTPSEDEEPEEEEEEAAAAEEGEEETVASGEESLGFLSRLPPGPAGLDCSALDRDPDLQPPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY
The following text describes a protein:
Function:
Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
Subcellular Localization:
Cytoplasm.
Sequence:
MTESINHSRRSLFNRRKSVVIRPPWVREEVEFTDVCTRCSACITACETKIIFKGDGGFPEISFKDNECTFCAQCATICPEEKLFDLSQTPWQHQAVIQDNCLTFQGIWCQSCKDACEPRAIGFTLSVGQAPMPKIDTSLCTGCGACVAPCPSQAISIKQPE
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MPLGFRNHTHALWRPGYHSLSRSVRFPADPAGSRSMEMHQVRYFLAVAQLLNFTRAAEECNVTQPSLTRAIKQLEAELGGDLFRRERPAAQLTELGQRMHPLLKQCYDAAAGARSLASSFKSGEVGALRVALTHSVDLALLIPHLNEIRRQFNRLEFRFLRGTSREVAEFLKKGEAELGIAAEIDEAWERLDVWPLFTEAFDLIVSREHRLAEHDTIEPDDLRAEQFLGRSYCEHSKRIAASLREHGIDVDHGHEISSERDLVELVEADIGIAMMPHTSPVPESLKRAAVAGLDARRTVSLYGVAGRQRTAVANAVMRMLRGADWRSIAG
The following text describes a protein:
Function:
Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTEQRKSLIKLISAVIIILLLPVLFFRFIGDDPTKKAVNSTRQIAVVNEDTGVLSDEVKSDEEDKSAQFGKEVAAVLGERPDYSWTVVNRSAAETGLASKKYDAIVYIPSDFSKNILSYDKDHPQKATLEFSIQDNLNAVNKEKVQRELEDAQKTMNKKMSALYWNFVSQKVDNIRGEFDKIVNKESEFQNVMYNFYKPSSNDLAGEIKQQKDLIDELKKSMNEAQGTTKEKASTAEEAKNTLKEFIDTVERYKEYQENQKKLLLAAQDSTQQQIRTGLDAIQAQQKANQFSERMSGLATGIGQAKTQIGLTNLALNNAEKLRQNQVPLQEMGMKKIENDMFNAFLSRYKSQYEAIKYQNLNQLQENIGKNRLSLLKPKESDEKEDGEDTSDNKDDTDKEDIEDIKLDLEKQRDELKNVATEIKDISEGLKEPEQEKPTTPDAEEPSTDDSPNTEEPSNDIPTSDDQPTNEDTGSSEEGTQDNGSQNDVQTNIETGQKHQESSKNVPEQDTNTENTGTSKTDFSLIELADENDGSNQSDGLQGDGADGETDISGAKKRLNEAAIKLEEIENALQEKQEEHNNKLEKHIDELNQEIKELNKTVSKLNDQIGDLTKKLVDFDNNVNDAYRLIYNLEDEIIQTLQSRGYIDQKEKLSSIFSSRIETDNISNLMKYYNSLNLYKSTLNDNLDLGSLTIIKGEVIQEQDGNVQSVLALTPEESASWEALKNNTMQTDEDINSFIDGMTKFADDYSGYIRDSQAGVLDELTKISESAAKASEQLVTGATQESATFSNDGLSGTMALSVQDTVGQEVLQMSDMMGSLSDRQSGIIDYTTNMQQSVNDVQAKADTLNNNWGKNVASTKLVRNDVYGILGNTLVDGQNNGYVYDYLANPLKISGEVPEEKIQTVPPVVILVIVLISSLLIGYFSSYYQNAPLLVKGALFGILNILVGLMISLFGLNIYSLPDDQTIKWSVFTILLLVASSAFIRTAFRFGSIPGWVASAAMILFYVAPLIDLIMPNFTFEDPVSKVYIDIQYGTGHLFTMGITVLLIITVIAVALPLIIRLMAEHTAESDETYEA
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MAAATARARRPHVLCFLLLVMVMPCAISAADLASDGRGRLYQVAMDQAARALAEARAARRDDPRDGVARRGAAQAWADCDQLVAFAVGHLNRTVAAAARGVDGDDVAAWLSAARTTVGTCLDGFGELGASPGPEFAAALANVSRLVTDALAATALRRGTENGARAATNSGDGDGRMLPLDMARPGDADVVVAKDGTGHFCTVGEALKAAARRATNGGGRTVVYVKAGVYNENVEVWTTNLMLVGDGIGRTVITGSRSVRGGYTTFSSATFGTPRSSLSLLASCECECVTLTWMDVHEAVNADGFVACGVTFRNAAGAGSGQAVALRASGDRVAFYRCSFEGHQDTLYAHTLRQFYRECAVAGTVDFVFGNAAAVLQRCSIRVRRPPLPGQPAVVTAQGRVDRYERTGFAIHGGRVTAAARFGAPGAAASAPFEAYLGRPWKEFSRVVYMEAYMDATVGAAGWLAWDGTAFAQSTAFYGEYRNSGPGSGTEGRVRWGGYHVITDPGVAAEFTAGEMVNAGEWLGSTGVPFTPGL
The following text describes a protein:
Function:
Probably involved with other LSm subunits in the general process of degradation of mRNAs.
Subcellular Localization:
Cytoplasm. Cytoplasm, P-body.
Sequence:
MEHSSMPLWLSSFEEEIDTYIFISSRDNKLYLGILRTYDQHGNVFLTHCVEKIIVPEKNYFSDVYVGNLIIRGDNIAYFGSVDEEKYCKMFDYTIKNDNDEEHNNMDMIKNKKEYSSSENIILVYKPINHILKFIPENNADSSIFEN
The following text describes a protein:
Function:
Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
Subcellular Localization:
Membrane.
Sequence:
MENQSWDFFGTPLGNSSTNQTLLDKMPQLPLEVQVVTIFLVLLICGVGIAGNIMVVLVVLRTKHMVTPTNCYLVSLAVADLIVLLAAGLPNISEVVASWIYGYAGCLCITYLQYLGINISACSITAFTVERYIAICHSIKAQLLCTVARAKRIIACVWFFTAVYCLMWFFLVDISQAVFSDGMKVSCGYRVSRNLYMPIYFLDFTVFYVIPLVLATVLYGLIARILFMNPLPASPQHGGRPSKHSSISTSSSMKLSCRGNKSALSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFMDPPYLNIWFVLFCRLCIYLNSAINPIIYNVMSQKFRAAFKKLCKCESKRTESTTQFSAPVFYSTMKDYSHDSSEHDITEHEDLNGYPSVARKSKSLK
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MAQNDPGSGNLMDEFEEAFQSCLLSLTKQEPNSGTNKEEIELEVQKTTNRFIDVARQMEAFFLQKRFLVSTLKPYMLIKDENQDLSIEIQRKEALLQKHYNRLEEWKACLSDIQQGVHNRPTPPINPGMLQGPSGMQQPMGGGVPPRPGLMPGMPPGGMSPVGPMPPGQQHMLQAQQMQQLRMMGKLPPK
The following text describes a protein:
Function:
Catalyzes the NAD(+)-dependent oxidation of coniferyl aldehyde to ferulic acid and which is induced during growth with eugenol as the carbon source.
Miscellaneous:
MISCELLANEOUS: The enzyme activity with NADP(+) is 4.3% of that with NAD(+).
Sequence:
MSILGLNGAPVGAEQLGSALDRMKKAHLEQGPANLELRLSRLDRAIAMLLENREAIADAVSADFGNRSREQTLLCDIAGSVASLKDSREHVAKWMEPEHHKAMFPGAEARVEFQPLGVVGVISPWNFPIVLAFGPLAGIFAAGNRAMLKPSELTPRTSALLAELIARYFDETELTTVLGDAEVGALFSAQPFDHLIFTGGTAVAKHIMRAAADNLVPVTLELGGKSPVIVSRSADMADVAQRVLTVKTFNAGQICLAPDYVLLPEESLDSFVAEATRFVAAMYPSLLDNPDYTSIINARNFDRLHRYLTDAQAKGGRVIEINPAAEELGDSGIRKIAPTLIVNVSDEMLVLNEEIFGPLLPIKTYRDFDSAIDYVNSKQRPLASYFFGEDAVEREQVLKRTVSGAVVVNDVMSHVMMDTLPFGGVGHSGMGAYHGIYGFRTFSHAKPVLVQSPVGESNLAMRAPYGEAIHGLLSVLLSTEC
The following text describes a protein:
Function:
Involved in the biosynthesis of the isoquinoline alkaloid sanguinarine. Catalyzes the conversion of N-methylated protoberberine alkaloids N-methylstylopine and N-methylcanadine into protopine and allocryptopine, respectively. Can also use (S)-cis-N-methyltetrahydrothalifendine and (S)-cis-N-methyltetrahydropalmatine as substrates (Ref.2).
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MRTESIKTNRPMDLLLQYLQPISVALVVIALVWNYGRRNPTKKLAPEASGGRPIMGHLHLFNDGELTHRKLGAMADTYGPVFNIRFGSHKTLVVSDWEIVKECFTTNDKLFSNRPGTLGIKLMFYDADSVGYAPYGAYWRDLRKISTLKLLSNHRIDTIKHLRSSEVESCFESLYSQWGNGEKSGEFAPVRMDSWLGDLTFNVVARIVAGKKNFSANGDVGAQRYKAAMDEAMRLMRFFAFSDVIPSLSWLDNLRGLVREMKKCASEIDSIMATWVEEHRVKRNSGGNSQLEHDFIDVCLDIMEHSSLPGDDPDLVVKSTCLDMILGGSDTTTVTLTWAMSLLLNHPQVLQKAKEELETQVGKNRQVDDSDIPNLPFIQAIIKETMRLYPAGPLIERRTMEDCEVAGYQVPAGTRLLVNVWKMQRDGNVYKGDPLEFRPDRFLTSNADVDLKGQHYELIPFGAGRRICPGVSFAVQLMHLVLARLLHEFEITTVEPETKVDMAESGGLLCYKIMPLEVLIKPRLEI
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MINQGLFIRVNNFQLLKASLAYKKASNILTFPPIRTSTKHGGGSSKNTGDSAGRRLGIKRSENQFVRAGEILIRQRGTKFHPGDNTGLGKDHTIYSLVSGYVKFFQMDVSLRKRRKYVGVVFDKETTLPRPKDEPTIRRVNKYITSANSAQVS
The following text describes a protein:
Function:
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Sequence:
MQRIIPIDSPFFLNPDELGTPADWTAVFGNDNPLALEIGCGIGDFIARTALDHPTTNFIAIDYYNKGCLKTCSRLERHGITNVRVVRAEARQFIVERIQKGSLAAVYINCPDPWPKKRHRKRRLVNTQFVRFIRDYLAPGGDFYFATDFDDYGEDVAAFMPQMPGYANMLAPDIFRHELEGYHLSKYMQKFMAEGKRIYFIHYRTTMEG
The following text describes a protein:
Function:
FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-decaprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-decaprenyl)benzoic acid. Also acts downstream of COQ4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-decaprenyl)phenol to 2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to coq6 from NADPH via a ferredoxin/ferredoxin reductase system.
Miscellaneous:
MISCELLANEOUS: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MSSLVLRGVSRVEMPTISPTLGIYTRKFASQKILQRQFDVVIVGSGPVGLALAAGLQSNPVTQSLKVGLLDIQDTMKLKDWKFETYSNRCSSLTNHTRMFFDKIGAWDFARKDRIQPFQHILASDGLTNSSIHLDQKPGSEPMAFMSENVNLQYALLNSIIDKMNNNIKKPNLEFLMPCTITKLSKGENIYRTHIHTTTHGELTTKLLIGADGRNSIVRKYANISMPGWNYLTHAVVGTLKIDPLKGPAVAFQRFLPTGPLAYLPLPDNNATFVWSTRPHIASKLLRLPEETFVKFLNASFRLDYPDLSYLYQMDFSEPSKVNEQLDWRLQVKRNSNMQVPPVITEIVSGSRAAFPLRLAHVDEYVKEGIALCGDAAHNTHPLAGQGLNTGIQDVESLISALSFAIKHGQDIGSVFSLQPYFRDRYFKNHVYLGVVDKFHKLYAMENPVVTSVRTLGLSLFDRSASLKNFILSTVANGI
The following text describes a protein:
Function:
Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer-coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein.
Sequence:
MMSQQLIDFIDSRTRHPYKSDEVEKFQQEVNELQLPDPNSLPILSEEEKRQAREDAAFRRSSEGLEDAWLDSAIPADPTPIFRDTVELLCVYQSFVKKSASLDTVANFLDFSTDFSTLSTKKDETEIAPDCLHYIAELLFQKKEREVKEKWKNELTEKLKTLFNWPAINPNLKESSKFESFFGFVRSIQSFKDSETGLPLFMQVYITPYVNQFRYHFMSQKQTNVLSKPEWFFEFLLKVFRSNRSFYMLMRDIKFFPGVPPFFTFINLLNNVAKEKLTHIIKYDDYLVHLVHETLQYSVRLEQHFHYTQDPLIIFLFEQNGTYDKWLGLETQLSLTKLEDIKIASDAWELESDQSDDFSSAVPTKMTVRFRDMIETTFSVLQNLPSLDYQFNFWRSVQLKPMMQYVNWLEAFYESHESSSSIHLPGSLQTDKSKFDIAEVERMCKLYSNFKLLMDWLDDIEDEDVYIRIGHKMGSENYAAFYQVKPRLSTLTNGSFRMILRAVSQTLRPLLDNYSDLDTWVIKEQLPGAALLSTSVSAEIVGFQSRLKEIIALLQKLLIGSSQCEAIYQIGTLVESWMIKIVMTHQFSVRGGVQFAMDAMQIVLEFSDYPLLKFERLMSTVELLSLESGENKLIKKLIIEINQKNYDFIDEFFKTKEITLSYEDALGVLYRRVDAWKD
The following text describes a protein:
Function:
Plays a role in determining ER morphology.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.
Sequence:
MLRVLGGLLGGKPKEHVIDKYTRDLTAVTFTIHELDKRLKRNDEVLMRWQHRLKIYGTTLVVLFGAMAYSNYRSLPVTGLTFLLGLLAILGLSRLLCKVFEYQRRNIVIKLDKARAQHQGTLEDLKKATNFYSTHSLIQRFSSGPLQSQDASTLMDEELQSKYDELQNLQKELAQLRGDSSGKSTNEAREETDRWFDKVLDVLSGGGFAIENNLVPVTCRKCAKTSGCYVVRNTEWTYVCPHCGEQQTNSAEPEGTTSRSPSGDMKDKNSTT
The following text describes a protein:
Function:
May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.
Subcellular Localization:
Nucleus.
Sequence:
MGSASPGLSPGPPGRLLLPPDSALRTGLEKAAAAGTGPERRDWSPSPPATPEQGLPTFYLSYFDMLYPEDSSWVAKGPGASTRVEPPDEPEQCPVIDSQAPGGSLDLAPGGLTLEEHSLEQVQSMVVGEVLKDIETACKLLNITADPVDWSPGNVQKWLLWTEHQYRLPPVGKAFQELGGKELCAMSEEQFRQRSPLGGDVLHAHLDIWKSAAWMKERTSPGAIHFCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI
The following text describes a protein:
Function:
Capsid protein self-assembles, with the help of the scaffolding protein gp11, to form an icosahedral capsid with a T=7 symmetry, about 61 nm in diameter. The capsid encapsulates the genomic DNA.
Subcellular Localization:
Virion. Note=Part of the capsid.
Sequence:
MAYTKISDVIVPELFNPYVINTTTQLSAFFQSGIAATDDELNALAKKAGGGSTLNMPYWNDLDGDSQVLNDTDDLVPQKINAGQDKAVLILRGNAWSSHDLAATLSGSDPMQAIGSRVAAYWAREMQKIVFAELAGVFSNDDMKDNKLDISGTADGIYSAETFVDASYKLGDHESLLTAIGMHSATMASAVKQDLIEFVKDSQSGIRFPTYMNKRVIVDDSMPVETLEDGTKVFTSYLFGAGALGYAEGQPEVPTETARNALGSQDILINRKHFVLHPRGVKFTENAMAGTTPTDEELANGANWQRVYDPKKIRIVQFKHRLQA
The following text describes a protein:
Function:
Catalyzes the NAD-dependent dehydrogenation (oxidation) of a broad array of hydroxylated polyunsaturated fatty acids (mainly eicosanoids and docosanoids, including prostaglandins, lipoxins and resolvins), yielding their corresponding keto (oxo) metabolites. Decreases the levels of the pro-proliferative prostaglandins such as prostaglandin E2 (whose activity is increased in cancer because of an increase in the expression of cyclooxygenase 2) and generates oxo-fatty acid products that can profoundly influence cell function by abrogating pro-inflammatory cytokine expression. Converts resolvins E1, D1 and D2 to their oxo products, which represents a mode of resolvin inactivation. Resolvin E1 plays important roles during the resolution phase of acute inflammation, while resolvins D1 and D2 have a unique role in obesity-induced adipose inflammation.
Sequence:
MSLGGKVAVVTGAAKGIGKAIAENFLQNGAKVVLLDVDETTAKGLKKVLDQKFGEEKTLFIRCNVESEEDIKAAFEATMATFGCMDILCNNAGILSEDQWERAVSVNLGGVIRMTYAALEKMSQQSGGRGGVVVNTASVGGLGPLASCPVYSATKHGVIGFTRAMAAASTASNYGIRFNAICPGAVQTDLFASVTNCLGPFSHLAHLFEKFAADGVLHLEGSAFYTKSSGKRGRFTQGKTCIIFLPGGRQTWLSVFWSW
The following text describes a protein:
Function:
May regulate transcription elongation by RNA polymerase II. May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex.
Subcellular Localization:
Nucleus.
Sequence:
MAIKNQATAICPEPKAKGPLENPPPPPPPPPEISISAAAAREREMGSAAPPAQIPTSFGHELRACLRCRLVKTYDQFRDSGCENCAFFKMDEDHERIVECTTPNFNGIISVMDPSRSWAARWLRIGKFVPGVYTLAVSEALPEDLQNLCEDERVQYVPPKRI
The following text describes a protein:
Function:
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Subcellular Localization:
Secreted.
Sequence:
MDGVTGLRVLLCLLTLQTMPALGLATGRPRGNEKRQAVDTTVNGVSIRSLKVNCKVTSRFAHYVITSQVVNSANKAREVAFDVEIPKTAFISDFAMCSTQISLGSASGRNMEQFTIHITVGAQSKATFQLTYEEVLKRRLTQYDIVIKVRPKQLVHHFEIDVDIFEPQGISRLDAQASFLSKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGDFKVTYDVNRDKLCDLLVANNYFTHFFAPQNLTNMSKNLVFVIDISGSMEGQKVKQTKEALLKILGDMKPVDNFDLVLFGSQVQSWKGSLVPASHANLQAAQDFVRRFSLAGATNLNGGLLRGIEILNRAQGSHPELSSPASILIMLTDGEPTEGETDRSQILKNVRNAIRGRFPLYNLGFGHDLDFSFLEVMSIENNGWAQRIYEDHDATQQLQGFYNQVAHPLLTDVELQYPQDAVLALTQHRHKQYYDGSEIVVAGRIADHKLSTFKADVRAHGEKQEFKATCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKTEGEERANLSSQILKMSLDYHFVTPLTSMTIRGLTDEDGLEPIIDKPPEEMVGPRRTFVLSAAQPSPTAHPIGSKLPTRVTGVDTDPHFIIYVPTKEDSLCFNINEEPGVILNLVQDPDTGFSVNGQLIGIKAGSPGQHESTYFGRLGVSSPTSDFQLEVTPQNITLNPSSGGPVFSWRDQAVLQKDGVVVTINKKRNLVVSVDDGATFEIVLHRTWRGSSIHQDFLGFYVLDSFRMSARTQGLLGQFFSPLDFEVFDLRPGSDPTKTDATMVVKNRQLTVTRGLQKDYSKDPRHGTEVSCWFVHDNGAGLIDGVHTDYIVSDIF
The following text describes a protein:
Function:
Component of the serine palmitoyltransferase (SPT) that catalyzes the first committed step in sphingolipid biosynthesis, which is the condensation of an acyl-CoA species and L-serine. The catalytic core is composed of a heterodimer of sptl-1 and sptl-2 or sptl-1 and sptl-3 (By similarity). Required for the specification of abicobasal polarity and development of the gut lumen.
Sequence:
MSRRTDSLCLDEYLSSELKKRTHILECAWNQEHDDDEEEEEVKVDQGSEETTSSHDIYGDVGKRAPNEFEKIDRLTTIKVYIAWLALFVFAHIREYVTRFGFVKDLSSKENAKMKDFVPLFSDFEAFYQRNCYIKVRDVFERPICSVPGATVDLVDRVSHDGNWTYEYPGTRTNVINVGSYNYLGFAQSAGPCAEQSASSIDREGLSCCTTVHERGRSVSQAKLEKLVAEFLGVEDAICFSMGFATNSMNAPCLVDKHSLIISDKYNHASLILGCRLSGASTKVFEHNDMESLERILRDAIAYGNPKTHRPYKKILIIVEGIYSMEGSICNLPGIIALKKKYQAYLYLDEAHSIGAMGKTGKGVVEYWGCDPKDVDILMGTFTKSFGAAGGYIAGSKRTVDHLRAASPTGYYSSPMSPPIAQQIYTSMSIIMGKDGTKDGAQRIERLARNSHYFRMKLKQNGFIVYGSNDSPVVPMLIYFPTMCGFYGREMLARNIGCVVVSFPATHMTEGRVRFCISAAHTKEQLDEVLETVNLLGSMSRSKFSKRSHLYKNQKIEW
The following text describes a protein:
Function:
Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis (By similarity).
Subcellular Localization:
Nucleus, nucleolus. Cytoplasm.
Sequence:
MDRTCEERPAEDGSDEEDPDSMEAPTRIRDTPEDIVLEAPASGLAFHPARDLLAAGDVDGDVFVFSYSCQEGETKELWSSGHHLKACRAVAFSEDGQKLVTVSKDKAIHVLDVEQGRLERRISKAHGAPINSLLLVDENVLATGDDMGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVTLMKCGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTESLLCTGSTDGVIRAVNILPNRVVGSVGQHTGEPVGELALSHCGRFLASSGHDQRLKFWDMAQLRAVVVDDYRQRKKKGGPLRALSSKTWSTDDFFAGLREEGEDSMAQEEKEETGDDSD
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MSDFNHKHEKVLTGLVFLQDAASRSSQLTNGMVNILTSFDERLARLEKTILPVYNETKNLQQKQENIDKTLASLDHVISYYSVSKEVEPVIKESPSSQGLEIFLQSLGRLQEAMHFFERNNPQSVELENVMSLFETGKDNIISEFKEHLAKHSQTIPATALLEALANDEEEISINHFSADVKDNLMQIADWLVTHNEDDFMNVYARFRANTVQKTLLGLRDHLRSSSTGALSHQGVSPVAAMSGTATLLAKSGVKASYDTPSRKTSKKLQQMLERKANQMLLKASQTLESSTGLALGSRRSAADSIKEDAVEEHEIESFLTEFTALLRLLQSELRLMLGIVPLPHQKAVLSIILRDALEMICHDAESLSGRARRSVSRQEFGPVLLLFPALRHLVCFKGDCDKLLEGCDSSVRTRFYAMVNNLHTTCGKALEDFAESVRSESAAPLPRDGTVYEMTSNVVLFLGQLTDLSDTVGPLLAQDQSYSNALVHTQPWPKPQRNKALLGLYIKKVLVQLNLTLVTKSDAYSDSSLRYIFRLNNSHYLLSALQRSGLLDLLKVVEPECEPIYREMINEQKRLYSQSWNKVLAPIWNSEDVPASVLLSGRLREKDKALIKEKFSTLNKEFEELSREQRGYSVPDVELRESLKRDNKEYILPKYQAFYDKYSNAQFSKHSEKYIKYSPAQISSVIDTFFDVAA
The following text describes a protein:
Function:
Involved in the uptake of inorganic phosphate.
Miscellaneous:
MISCELLANEOUS: Present with 504 molecules/cell in log phase SD medium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRFSHFLKYNAVPEWQNHYLDYNELKNLIYTLQTDELKQETPTGDLNDDADSQTPGPIADIESNIAAGEPSSSKRRFTHKLKRKLFGSKTPSGSKRGDSDEKAIDGNNINEETIELDELSPQGKTTSFNKNFIRKKFFESRSSSVSSEGKTLFSSYDTFVTNLSDEKLKVDDFYKRMEAKFYERFDHLINDLEKEGIVTRLNETFNPEIQALPPLREIISGTSETHSSNNPFEIHSSNIDSELRNRFDYSEEEMDEDDDVDVFADTTDNTALLNYSQFNIKSQKKSLLKQTIINLYIDLCQLKSFIELNRMGFSKITKKSDKVLHMNTRQELIESEEFFKDTYIFQHETLSSLNSKIAQLIEFYAVLMGQPGNVDSCKQELKSYLHDHIVWERSNTWKDMLGLSSQNNDIITIEDEAEKLMQEKLQIEYFKYPLPKPINLKFTKIENLAVPKLFFGKRAMKIGFIIIVTGVLLGVKTFNDPVEHRCMALVECCAFLWASEAIPLHITGLLVPLLTVLFRVLKDDDGKVMGAAAASTEILGTMWSSTIMILLAGFTLGEALSQYNVAKVLASWLLALAGTKPRNVLLMAMSVVFFLSMWISNVASPVLTYSLLTPLLDPLDYTSPFAKALVMGVALSADIGGMASPISSPQNIISMQYLKPYGIGWGQFFAVALPTGILSMLCSWALMILTFKIGKTKLEKFKPIRTRFTIKQYFIIIVTIATILLWCVESQIESAFGSSGEIAVIPIVLFFGTGLLSTKDFNTFPWSIVVLAMGGIALGKAVSSSGLLVTIARALQKKIQNDGVFAILCIFGILMLVVGTFVSHTVSAIIIIPLVQEVGDKLSDPKAAPILVFGCALLASCGMGLASSGFPNVTAISMTDKKGNRWLTVGAFISRGVPASLLAFVCVITLGYGISSSVLKGST
The following text describes a protein:
Function:
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD) (By similarity). Has been shown to be activated by activin type I receptor-like kinase-2 (ALK-2) which stimulates heteromerization between SMAD9 and SMAD4. ALK-2 binds TGF-beta, activin and BMP.
Subcellular Localization:
Cytoplasm. Nucleus. Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4 (By similarity).
Sequence:
MHPSTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQSLGPAPPSSPGHVFPQSPCPTSYPQSPGSPSESDSPYQHSDFRPVCYEEPLHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus.
Sequence:
MKDGLKDPRPVTDKTFKDMCLSNLFSVIISSCPKTTPTWSAQKAFRAPGNSISKGMFEFLLQFMAFPENYRLEGKLEDSFPELMNLLKYPIVIHKRYLQTVGVPHQWPYLLASLDYIKNLIENVSDPYEDILDWISVENRFKHLMGFFFQEFVKFTDKTYTVFLQTGEEEFVEETDILMQNIVQHPNLKEENEKLFEYSKKLEEEVEAAKKKLLERREEKVTQDKELKQYEKQLASLKQLNKTGQERKISMENYKQIDELQKLVQLREQELERQEQLGFNVNQLDAERKTILTKYETMEGRRKELEEETLKLSEMRKEKKDEILKKVSMLEKCIRECFIMTKEEEDVMFALKFDINDGESFDCDVITLKNLVYKQIKPRVERELMEDQATLNNDRLRDLTQKLQVIKNEIISIDELTRKVEEDMLRKKEEHEVYVSHRINQLKNLEGELEMMKKKEESMIARCEEAERNLKELEEKKMKDREEHLKDFEEWAVDFKKQNIKALKMLSSAQVVSIMAILEPCSKLLSFFPPETFNQFKKYTKKQTRNIEKFLSQVAGLDGDSHLATVKFKQINVDLEDKRVQIVHIWKYQSTARTLHHQ
The following text describes a protein:
Function:
Caffeyl-CoA reductase-Etf complex catalyzes the reduction of caffeyl-CoA to yield hydrocaffeyl-CoA. It couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant. It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction. The electron transfer flavoprotein (Etf) mediates the electron transfer between the different donors and acceptors. The complex can also reduce 4-coumaroyl-CoA and feruloyl-CoA.
Subcellular Localization:
Cytoplasm.
Sequence:
MRILVCAKQVPDTNEVKIDPKTGTMIREGVPSILNPDDANALEAALVIKDENPGTEVIVMTMGPPQASEMLRECLAMGADEAYLLSDRAFGGADTWATSATLAAGIKKVKKVDLVLAGRQAIDGDTAQVGSQIAQRLKMPVVTYVEDIKIEDKKAIVHRQMEDGYEVIEVQLPCLLTCVKELNDPRYMSVGGIMDAYEQPITIWNHEDIGLSPEACGLNASPTQVFRSFSPPAKGGGEMITGTTVNEVAGSLVSKLKEKHII