lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required in S.pombe M (minus) cells for production of M-factor pheromone. Involved in the transport of the farnesyl-derivation of the M-factor pheromone.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHIHSDLSLPQFEHASIDPPSYSPQKSSFEEKKHNFSITNKSLETLRSQESPCSTTFPVSDRKDALLNIPTVVDDEFQHTEELAGVSSWSDFFYLFHFSDIPLIFGTLIFTCLSAALEPLMTWTTGKVFDALSQYATSQITLGKMISLINFNSLLITIFGLASCVFSFGVRFLWQYLSAIAGKRARSLCFHVLSSKSSTFYSLTESKSGLVNSVDRCIQFYEKSISLPMFHIAENLAISLSCLIISFRYSWSLTLVVLASYPIIILVVGFINSFLSSAYEKDRKSSEKAASILEKSISAIQTVIFHSMQDTEYRYFADACSTSSKSFLRFSFLDAFQGGVSQFFLYSVFFQGLWFGNHLATTKRVNVGQVVTVFGSCLSVASSLQQILPAIPDLIKGKFSSHFIKTLCESHDPIEAAKRSAAKIKSISFERGFRFDNVSFAYPSRDENLFSLINVSVFIPFGELVHIIGPSGSGKSTFISLLLRYFSPTYGNIYLDDFPLEEIDEHVLGSTITLVCQQPVIFDMTIRENIIMRNENASESDFEEVCRLALVDEFALTFDQSYDTPCKEASLSGGQQQRIALARALLRDTEILILDEPTSALDPITKNLVMDAIRAHRKGKTTLVITHDMSQINNDELVLVIDKGHLIQRCARKELVLFEDFENNVSIDEKVLKEEADNPFILPNEESLLEKYWINYNESFSQLSRESLFTSLESPFTDIESPTIVSRRKIVEQRKLRMEKESFQETNVDQTFHLFDDKEHACSLTLIFKSIWKVKKLRWFFLLGLLTSLIQGASVPIFAYVISKCLNLFMQIDPSIGVAFWSSMVLVVAAGSGASYFFSHYIFSISAKIWCDHYRLLAVKVLFTQDQAWFDQIENYPLVLSKILVNNISDMRNMISSLIEEVFIAFTMAIIGIAWSFATGWRLAAVLVAVSPILCLTSRMFSYIYVSTERMCQDVVISTTSILHKTIVNLDTIKGYSVLSFFRENHKNSLRKSWEAFKRRAFWTSLGFAINNSLLYFVRALLFYCSSIFISKEFYTVEQMVQVLSLATFTLLMASTCIMSLPNVSASRIATSRVLKLSSLKPGNLHKSGYLKFPLVGKIEFDGVSFAYPDSERNHLALNNVSLSIEAREKVAIVGISGSGKSTLVELLRKTYPSEDIYIDGYPLTNIDTNWLLKKVAIVDQKPHLLGSTILESLLYGVDRDINSVMDALDKTYMTEVIQNLPNGLDTPLLEFSKNFSGGQIQRLAFARALLRNPRLLILDECTSALDSKSSLLLEKTIQNLSCTVLIITHQPSLMKLADRIIVMDSGIVKESGSFDELMNRHTHFWKLIHRGEWIE
The following text describes a protein:
Function:
Member of the two-component regulatory system PgtB/PgtA that regulates the inducible phosphoglycerate transport system. When activated by PgtB it acts in conjunction with sigma-54 as a transcriptional activator.
Subcellular Localization:
Cytoplasm.
Sequence:
MLNDECSILLIDDDVDVLDAYTQMLEQAGYRVRGFTHPFEAKEWVKADWEGIVLSDVCMPGCSGIDLMTLFHQDDDQLPILLITGHGDVPMAVDAVKKGAWDFLQKPVDPGKLLILIEDALRQRRSVIARRQYCQQTLQVELIGRSEWMNQFRQRLQQLAETDIAVWFYGEHGTGRMTGARYLHQLGRNAKGPFVRYELTPENAGQLETFIDQAQGGTLVLSHPEYLTREQQHHLARLQSLEHRPFRLVGVGSASLVEQAAANQIAAELYYCFAMTQIACQSLSQRPDDIEPLFRHYLRKACLRLNHPVPEIAGELLKGIMRRAWPSNVRELANAAELFAVGVLPLAETVNPQLLLQEPTPLDRRVEEYERQIITEALNIHQGRINEVAEYLQIPRKKLYLRMKKYGLSKEHYKF
The following text describes a protein:
Function:
Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
Subcellular Localization:
Cytoplasm.
Sequence:
MRHKIRLIDFILLRFIEERMKVARDVAKEKKKTDSPIVIRDIEEQKIKEILDRTDLNPVRMRRIFEEIMKLAKEEEYRLLGISKTVAVLGPMGSFSDEMAMKLIGSRIPLKYCSTTDEIIEMVEKGEVDYGIVPIENSTYGTVIPVLDALLNHEVEVFGEAKLEIHHCLVAKKKLDLKEIKRIYSHPQAISQSLGFINTYLSHAEIRYTSSTSDAVNLLDDESAAIMSESAAKMYGLLILRRSIQDLKEKNITRFYIIRRKTGKMEGKYTSLFFGVQDRPGSLKAVLDIFASRGINLRKLESRPARTFLGDYVFFVEVEAPLKEEDIRDLERVTAFYKIIGVFDEVEELDVFK
The following text describes a protein:
Function:
Involved in cellular auxin homeostasis by regulating auxin metabolism. Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPAGAPSRSFPLQTALESRPWGSTSSFAVFSDLSLQGLGSPSSAAVNSFRQLGSLGSVAGPVHIVSQRSRSSRLANPVFLEHPRALGRKGRQRKVAVASLPAANQALNQGVSQALSEGGLNQFAELAVGAAKKAFNVGVLGATAGASLKLFTVCALVVWMQKSGRLPESTPAVLSQVAFRLLIPCFLMSKVAVTLYSDFSPALLAVPVAAIVQILLGAGMGRLAAHFAYREPPLVPAHFEAHQPTRASSLVAASVAIATGQPDVAVALTAPKGVGAAKLGASKEALMTATSAFGNSLTLPLVFLSALLDRAGADKAAGYLALYMVGWSPALWTFGYKIIAGSSDDPENGDESDYEGEGRWQAFLTWLGRVMNPPLYGVFLGLIIGATPLAHLFLPPATAAAENLANATSITPLTVLATLTSGVFRPVMEAASLLGTATLAVQTVVLASSLAASIPSRLHSFSGGAQPFVATPGANPNPLTDALREGEGPVDSVVSESSSLKPRRRKTGRLKPGPDPANVLDGRAVWVVSGVRLLLLPLVNLFLTLGLMRAHILPADPICGLVLMAEAAMPSAQNLVLLAQLKAKTRPLAGMVAGLLLRQYALSILPITFWMAIFLSVLGLATLQPEGSPPGRLLKAASESLHWQPEPLQAVCSQRANNRMRGKHPAILNKVKLNLGPANCTATSLQTAPRLRRRASRDWSRKNGKASV
The following text describes a protein:
Function:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MLAESLRLAAEQGDQGEQTTNTTKRKKTAPGEGASSLFLFSEDNFIRKQTLILTIIANCVVLALEEHLPNHDKTLLAQNLEATEMYFLAIFCAESLLKILALGFVLHKGSYLRNVWNIMDFFVVLTGVLTVLMQDVNLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGVLHKTCYSLYDIDQIVTEGEDEVPCTTDNETQAKLSGSNWCRDGNSVCLERWEGPNHGITSFDNIGYAMLTVFQCITMEGWTPILYWMNDAMGSTFNWMYFVPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQEFLKMRRQAQLERELNGYVEWICKAEEVILAEERTTEEEKLHIMKARRRARKKKLKKIGPSKSTDTEDESEMGDDDSKKSFKAFGRSARSQGDGKWAKFWRSEKRFRYKIRHTVKTQWFYWSVIVLVFFNTVCVAVEYHGQPQWLTDFLYYAEFVFLGLFLSEMFVKVYALGPRIYFESAFNRFDCVVISGSIFEVVWSEYKDGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFDDETPPTNFNTFPIALLTVFQILTGEDWNEVMYLGIEALGGHNNGGMIYSLYFIVLMLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQAEENREKQAQELEKEMEALQMDGHTVFSMSPTKETKKKKEEKVEEEEVEGPKPMLPYSSMFILSPTNPVRKFAHGIVNLRYFDFFIMVVICLSSMALASEDPVNEESKWNNALDKLDYAFTVVFASEMFLKIIDLGIILHPGSYLREIWNFMDATVVICALVSMGFNFAQKKAAANLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCLVNSLKNVINILIVYILFHFIFAVIAVQLWNGKFRYCNDASKITEATCQGQYFVYDEDSDVPRAEQRQWTIQSFHYDDVMMAMLTLFAVQTGEGWPQVLQHSMAATYVDQGPIENYRLEMSIFYIVYFVVFPFFFVNIFVALIIITFQEQGEAELQSGEIDKNQKSCIDFTVQAHPLEQFVPETTHGFKYKLWKVVASTPFDYFIMMLIVFNTLLLMMKYDKQGETFTLTLKYLNWLFTGLFTVECILKIVAYGAGYHQAPPMLSEILTTMNKFFIMLFLCETVLKLTAFGIKNFFKDPWNVFDFITVIGSIIDAGVVELGERAAKIAKQHPGNLDKKLSTGDAIVKWIQENFFNVGCLRLFRAARLIKLLRQGDTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKEDPETSITRHNNFRSFTQGLMLLFRCATGESWPNIMLSCVKERPCDPAAKKAPNSCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFIRIWAEYDPKATAKIHYTEMYEMLKNMAPPLGFGNKCPNRLAYKKLIRMNMPVDDEGKVNFTTTLFALIRENLSIKMRPPDEMDQADEELRETIKIIWPLQAKTMVDLLVPPNDLLNSGKLTVGKIYGGLLILENWRNTRFGQIQSSTGFLGFGNRSSANQTVINIESGSDSRRQSSEGTRSQYLDLPNSDRHVRSPSVRSTSSRRKSRQDFGIADTVSNFMEFVKHEQRTNSNKRRRRDHWSASSTPAHTPFTRNTRHNDSLRSVRRAHGTTSLGQRSRSPSPKRQESSFSNNPTPTSRYRQGRRLPPTPSKPSTLQLQRPGGVINFPRLTPSPTHFTLQMPAHAKNYHRDRQFIPATGVAPLTGGSRVPLSFEQGMTLGRGGRILPSPVPNGYKPKTTRLLHSDSDDDDWC
The following text describes a protein:
Function:
In addition to 3'- to 5'-exonuclease and 3'-phosphatase activities, ExoA was shown to make single-strand breaks at apurinic sites in DNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQETKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEIGAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEKPVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPERYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL
The following text describes a protein:
Function:
A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
Sequence:
MAYSEKVIDHYENPRNVGSFDKEDPSVGSGMVGAPACGDVMRLQIKVSPEGIIEDAKFKTYGCGSAIASSSLVTEWVKGKSIDEAAAIKNSEIAEELELPPVKIHCSILAEDAIKAAVADYKKKHQH
The following text describes a protein:
Function:
Required for the activity of the plastid-encoded RNA polymerase (PEP) and full expression of genes transcribed by PEP.
Subcellular Localization:
Plastid, chloroplast stroma, chloroplast nucleoid.
Sequence:
MATRAWVAAAVALNPQLLPLRSCSPTKSVSPAQRSASMGLRLRSGRPCLGKFVCRRAKNAGYEDYKFPDPIPEFAEQETSKFREHMAWRLEQKKEDYFGDHVEEIVDVCTEIMGTFLENDYRGPGTLLVHPFLDMKGEIKERGLPGAPQAARAAIAWAEKNVDKDWKAWTGEY
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in flagellum axoneme, which is required for flagellum beating. May serve to reinforce and thus stabilize the microtubule structure in the sperm flagella. Involved in the regulation of sperm motility.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme. Note=Localizes at the ribbon and inner junction (IJ) between A- and B-tubules of the DMTs.
Sequence:
MASEKDDGPALPKLDDDNQTAENTCKPAEEQPQQLRWDDIHLPRFSLKQGMIPTRYVMPWKENMKFRNVNLQQAEACGIYAGPLEDSLFWGYSERLCHGEDRKAVLKKGLPEIKITDMPLHSPLSRYQSTVISHGFRRRLI
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MAAIQETGSASFLDPEIKMEVHGSLGPEAEEVVEGESLPKMGSSAEEAEEMLKQKSKEEASRNWNAQFEDFLKTLQFPSSTGKATQHTAPRTLPRRMAETSHSPKGVWVTPNQPLLLGEATGDDECYPVATHPGKEVTSSQKGSVGLEAQRQHFRMLIYQEAVGPRNFWRKLRKLCRKWLVPEKHTKEQILDLVTLEQFLTALPPDMQKWLRGRHPQTCSQAVALAEDFFLMHRGPKGCERQITETSKDMFANPPKAKEAQPRMKLRAETVHKHIGNENIVGDAQLTESEEPQLESNKEMEQLMTPVKIEDPFVPAQGVCKSDRAPTVCEEENAEKYDKNGKHFSQDSHLLIQEDPDVEKIYKCWNCGQNFSSSSDLLTHERNHVGEKVYTCAHCGESERIHKGQKSNRCPHCGKTLEDTLETGEKPYTSSKRGKRRSQRSEILQPERTCRGRKPSTCLVCGKSFRNGRALRTHQRIHSGSARLIESKGKKTRLQDTESVEQLMASTKTCKEDNFLCLSEPDKNQEGTDNNNGNGKEKVENGEHFSQDSDCIMHEGPDVEEKPFKCWHCGQSFSSISDRLTHEKTHVGEKVYKCSQCGESVRTHKGRKPRRCSHCGNTFGYNPTDKIQAEEKPCTSLGRRKNCKQTSNLLKHKKTPATGGKSCPKCGKTFTKASYLKMHQRVHTGEKPYKCLQCGRCFTWSSHLKYHEKMHTMMCFYCGKSFSQESIRVEHEKTHAEDNTFACFACGKAFEVSSELSAHAQTHKGKSFENSLLLKPYGNSLQHTAHQEVLVKESRECSECGKTFRSASYLKVHQRIHTGEKPFGCFRCGKSFTWSSHFKYHEKMHTMCFYCGKSFCQKSECVEHEKTHAGDNTFACFACGKVFGNSSKLAAHVQTHKGKTGENSMQHTAHQEVQTGEKSYKCSECEKTFRSASYLKVHRRIHTGEKPFKCLQCGRSFCWSSHLSYHEKTHQKIRTGKKPYKCSHCGKTFSWRSQLLLHEKKHKGEKACKCSICGRSFDRRSSLILHVRSHTKQAAYKCADCGDSFTSNTILQRHKKIHALAPEVPDSS
The following text describes a protein:
Function:
FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-polyprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid. Also acts downstream of coq4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-polyprenyl)phenol to 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to coq6 from NADPH via a ferredoxin/ferredoxin reductase system.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MRRATIRVVIPVVRWQKFRCLSQVTDGVPQVSSAQERPTNTSRESGDDQFDVVIVGGGMVGAAVGCGLASSALTRSLRVAIVDGNPATKEKYNKKSDAVPDSRVSAITPATVRFLKDVGAWENIQRSRHAPFDAMQVWDYSGLGYTRYQAADVGEDFLGYVVENNLLISSLASALERTGFAEIICPATVQGVQFPAKTSSSSARNLFENLSERAQSHIGASTCVREQKNVGQTSPNSFALNDDWAQVMLEGGRLLRTRLVVGADGGRSRVRDMAGLETRGWDYNQHALICTVRVGYHHSTAWQRFLPTGPLALLPVGEDMSNIVWSTTPEKAKELKAMSKEDFVTAVNRALTEDFGPLPSSRMGGPFNSKWLTPLFGEMPPSVSEPFIAPPPVTACLSDRLSFPLSLRHATKYVSNRVALVGDAAHTVHPLAGQGVNLGFGDAATLVETLREGIKTGQDIGELALLEKYEKERLWANLPMMAVLDGFQRVFGTDFPLLNIARAGGFNAVQYIGPLKKRIISFAMGS
The following text describes a protein:
Function:
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
Subcellular Localization:
Cytoplasm.
Domain:
Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
Sequence:
MIGPPGAGKTTIAGQLAQVTGMAVIATGQQLRAEIRAQSALGRYIEPLLEQGQLAPDSVMAELMRNWLQRIPIDQDCLLDGYPRSVAQAHMLETILADLGRRVDAVIVLTLDEATIVHRLSGRRICRRDDGQDITVHIDDTAKIAQCLARGGTLVQREDDHPDVIRTRLRLYEQETAPVLNYYTGRVPVHYVNADQSPAAVVALIRDII
The following text describes a protein:
Function:
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Sequence:
MHPNDVFSVLGIGSLCKCFVLMLFHRETCSMPVSPESCSLVQGFLAESAGRLFLGHAQTQLKTGLQTQERHFFLFNDTLLVAKAKSPTHFKVKSQVRVCEMWTANCMEEVCEGSTNPDRSFVMGWPTCNYVATFSSEELKDKWLALINGRISEGKEKDDPKTVPLKIFAKDIGNCAYAKTLAVNNTDTTTDVIRMSLQQFGISSCIKDLRLWVNSSKDDPPYPLIGHEFPFCIKMSHIRDGGSCPGRIGRDPMSPTDCPGVLLLDQCLPPDTQCQFILKPNKVLLSPQELLEPGQHKTFKRKRSLINWPFWRGSSSQLDGLPLSPTFSAAQGRLFGRPLSSVCSADHGLPKPVMDMLVFLYLEGPYTKGVFRRSAGAKACRELRDRLDNGTDNPEIKHQPMFVIAAVLKDFLRNIPGSLLCADLYDQWMDTMEQEGGDQKMEAIQRLLPLLPAENLLLLRHLIAVLHCIQGNAQENQMNAFNLAVCIAPSILCPPAPNTPEMEGEATKKVCELVHFLIENCSVLNALVLYADVSRCCSDSLLADVSSFQMNDSSYDSLENELNDDPESPYQEQLPLRDKDKPDSCSRDSVITLSDGDPDPDHDSELTLQLPPQARPRKFSPAVRQPRARQANSSLQGPRRLRRCSEPALVLAPTPSLNSTVAHGETRHQPVRKASYDASIEGEGEEDEVFLERELGRLHLKEEGRDGSEKKAAKASTCGKRKAKPAPPPPLRLDASCSSLSSPATSPTGSSLSSLDSAFSQYSTDYTVKWPVSQQSPRDSPPQREATPHLQSSSHPQPTSQTTSHGLHPNTWLKRDRRLSLKQSEDGQSEGSSVGNGTPLLANNGHSAANQEAGTVKQNCHQRSGSPPSYHQALLQLQRNRSPFYRGTEKAPTVKELRQLHDPPATYRTSKPTSPNNLKLLQSEGAQRLAGTGKHVQPPKGIFFGQNASNLILQRPKSHSLTPPMDVHKLSKTLPRRASEPAKVSADSHHSTSLTLDRLPAFKAKCQDARLGLADSEPHHSASPFCLSSSSARAVRDYFCSQGQEDPEACLQRSQEVVVAIVQGKEWQSKRCSDPPMEDFEQLFFAEESYV
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MVAKVAAPEKDASTEQQAQDKLRSLLPKEVLEVFDKNFKEFAKVQWGDYYYGNKGKKKSWALELVHSANQVIPSFNELFDEETFYVFAFCLVVFCIVLAIFLARCVGVKIKEHDIHAGLKLLAHEDVVVESPTGSGKTLAFLLPALTIMKRKPKWEGNEIGLLVICPSRDLALQIAQVAQPFADALGYSLHATIGGKKIETDLKKIHAGVNILIATPGRLERLIDGDIREGKLKRMLRCIEIFIVDEADKFTEVSFAASMSTIIPCLPKQRRTGLFSATQAKDKLDLAPFTLRTPAHIKLADQKDVISPSSLSAFYSIVKADEKLCALVEFIRNVPDKKILVFFASCQCVQYFNMILPRILSKRKIFAVHGKNKKGRFTQMSAFRKAEGAVMLSTDLMSRGIDIHDLDWVVHFDIPKKSSWFVHRCGRAGRNGREGSSVLIATPGQAAYVNFIKQHEKMEMKEMKLKTVTELKAEQLREKVVGLASKSREILEHGTSAYVSWLKASTTNDASIVCKFKELDIIGHAHAFGLLRLPKCKETYERDVSTFKRSGIDTSTIQYENKSLEEKRKEIRAKNEKRKDIYKEKEANDPRAQLKKKIKEKREGKNKKNKGENKIKKTERDEKENGEEEKKVEIGEKRKMKGDKKEKTKKRKIDSIEVE
The following text describes a protein:
Function:
May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MDKGRERMAAAAAAAAAAAAAQCRSPRCAAERRGFRRELDSWRHRLMHCVGFESILEGLYGPRLRRDLSLFEDCEPEELTDWSMDEKCSFCNLQREAVSDCIPSLDSSQSTPTEELSSQGQSHTDKIECQAESYLNALFRKKDLPQNCDPNIPLVAQELMKKMIRQFAIEYISKSGKIQENRNGSIGASLVCKSIQMNQADNCLQDEQEGPLDLTVTRTQEQTAQQGDGVLDLSTKKTSIKSEESSISDPSSENAVAGRLHRNREDYVERSAEFADGLLSKALKDIQSGALDINKAGILYGIPQKTLLLHLEALPAGKPASFKNKTRDFNDSYSYNESKETCAVLQKVALWARAQTERTEKSKLNLLETSEFKFPTASSYLHQLTLQKMVTQFKEKNESLQYETSNPPVQLKIPQLRVNSVSKSQADGSGLLDVMYQVSKTSSVLEGSALQKLKNILPKQNKLDCSGPVTHSSVDSYFLHGDLSPLCLNSKNGTVDGTSENTEDGLDRKDNKQPRKKRGRYRQYDHEIMEEAIAMVMSGKMSVSKAQGIYGVPHSTLEYKVKERSGTLKTPPKKKLRLPDTGLYMTDSGTGSCRNSSKPV
The following text describes a protein:
Function:
Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasmic vesicle. Note=After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.
Sequence:
MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQSKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWHSDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSMEIIEVS
The following text describes a protein:
Function:
Provides the (R)-glutamate required for cell wall biosynthesis.
Sequence:
MKIGIFDSGAGGMTVLKAIREAYPNVDVVYLGDTARVPYGIRSKETIVRYSKECANFLKDKGVDLLVVACNTASAYALEELKREFPFPVFGVIEPGVKEALRKSKTKRIGVIGTQATIKSGAYQEALKRAGAEVYSKACPLFVPLVEEGMIEGEIPKKVVEHYLKDFKGKVDTLILGCTHYPLLKREIQNFLEGVNVIDSSRATAKSLKDFVKNEGSGSLELYFTDRSQNLERLIKLILGEEVEPKITSEVFVL
The following text describes a protein:
Function:
Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
Subcellular Localization:
Secreted. Bacterial flagellum.
Sequence:
MASISSLGVGSGLDLSSILDSLTAAQKATLTPISNQQSSFTAKLSAYGTLKSALTTFQTANTALSKADLFSATSTTSSTTAFSATTAGNAIAGKYTISVTHLAQAQTLTTRTTRDDTKTAIATSDSKLTIQQGGDKDPITIDISAANSSLSGIRDAINNAKAGVSASIINVGNGEYRLSVTSNDTGLDNAMTLSVSGDDALQSFMGYDASASSNGMEVSVAAQNAQLTVNNVAIENSSNTISDALENITLNLNDVTTGNQTLTITQDTSKAQTAIKDWVNAYNSLIDTFSSLTKYTAVDAGADSQSSSNGALLGDSTLRTIQTQLKSMLSNTVSSSSYKTLAQIGITTDPSDGKLELDADKLTAALKKDASGVGALIVGDGKKTGITTTIGSNLTSWLSTTGIIKAATDGVSKTLNKLTKDYNAASDRIDAQVARYKEQFTQLDVLMTSLNSTSSYLTQQFENNSNSK
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC).
Subcellular Localization:
Nucleus, nuclear pore complex.
Sequence:
MPGMPADSGGAIVPFSGEPKHAASAPPVRPIRHGVPPPISRVYISWSSGNLLQVACLRPPGPEEGARRGPEEVGGRVVEVNLGVGAGNGSTEVEEEVDEAEMRRIEYGSVPAFALLQSRKNALADAAAMQHMHSVSEHAEWWQYVLEYSKTIGNLLGNQDCLPALMIENPRAILKVREKSTSLKAAWELLEIFYVDKELHSWLPERLVDWLADYDSLLTKTDGTVYFKLNNFQKKLINLQIVENDDDYWNGLSAALSVGWLDVVVNMLRFHGSYQLDQMDNRETENGLVEAVAVLVSTMPRMRPDLPKGKLGQCCKTRPDFIKAWEKWRGQVSKLECSAFWIQCSHQKTRDGLKNLLHIMMGNIKDLTAATSHWLELFASHFLYIRPFTVGFEGMHHLAQKCIQLKPSFDTNGLTGLLNGILSENPEVVLAECTKKFGPWMVTHCMELLAADNDYADIMLHEERPNFGGISIEELHRLVYAQVLCSHSLTWQIAPTYLSSCLNQGLGLLEILLLKQPIQDNRLVLKTLELCRLYELENVGTNIMKIAGIYHWKHGRKGTGVYWFQQAHDKVRLDRIAQQLFERIGKSVADDNFKQWEGLLELLGSDIGSAGGLEFLHRYRDFKRSLQQALEGRTGEAARQTVEFLIQLMRNPSTPQRFWLPLLHDSVKLLNCKPCPLLNVAETTLLLNKLQELSMAKLRPDFCSNHLPSHALSSVRLALGSNLARAILEEA
The following text describes a protein:
Function:
The nitrate reductase enzyme complex allows E.coli to use nitrate as an electron acceptor during anaerobic growth. The alpha chain is the actual site of nitrate reduction.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Domain:
Apoenzyme contains at least 2 NarJ-binding sites, one interfering with membrane anchoring and another being involved in molybdenum insertion. The first binding-site is a short peptide sequence near the N-terminus that contains a twin-arginine homologous motif.
Sequence:
MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKIVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRYTDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIGFRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWAEQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVDYTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQGKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHDSAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIGNGGKGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAWAALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKEVIGQKSNGNQEKALNFLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKDLGIADNDWIEVFNSNGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAHLAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK
The following text describes a protein:
Function:
Mediates the nuclear localization of the ribonucleotide reductase.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MCLYVNKEHPYTQASGPWPACLPRRWQLYKDQRRLHRPGGRRPMSTSDSHLGSPRKRQLQRAAPAAPQHSEYQQQLSTLGMRIRQAVDNGYRAPQDPVRAAVPHAVPAAACVQDNTLYTVPDYKRVPLAADRAPPMLVNQRTVSSTSSLQAWESQLDERLSLIDSSIMHNKLGAGEFMLGGTKRAFDQLETDNW
The following text describes a protein:
Function:
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 or PEX21 receptors. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 (or PEX21) receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
Miscellaneous:
MISCELLANEOUS: Present with 7900 molecules/cell in log phase SD medium.
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MSSTAVPRPKPWETSASLEEPQRNAQSLSAMMTSNQQDSRPTEESNNSNSASESAPEVLPRPAALNSSGTYGESNTIPGIYGNSNYGIPYDNNPYSMNSIYGNSIGRYGYGGSYYGNNYGSFYGGGYGAGAGYGMNNGSGLGESTKATFQLIESLIGAVTGFAQMLESTYMATHNSFFTMISVAEQFGNLKEMLGSFFGIFAIMKFLKKILYRATKGRLGIPPKNFAESEGSKNKLIEDFQKFNDSGTINSNEKATRRKISWKPLLFFLMAVFGFPYLLNKFITKLQTSGTIRASQGNGSEPIDPSKLEFARALYDFVPENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIEIIKRRKKIEHVDDETRTH
The following text describes a protein:
Function:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAAAASSTLHGVGAVASAKPRSAAPAAARRSVRVAAAAKGGAGSARGRLVARNAVAVTCWLHPRLSVMCSRLQRCADLFALWYVQAKADEAAAEAGSKSGGHELLMFEALREALIEEMNLDPTVCVMGEDVGHYGGSYKVTKGLAEMFGDLRVLDTPIAENSFTGMGVGAAMKGLRPVVEGMNMGFLLLAYNQISNNCGMLHYTSGGQFKIPVVIRGPGGVGRQLGAEHSQRLESYFQSIPGLQMVACSTPYNAKGLMKAAIRSENPVVLFEHVLLYNLKEKIPDEEYICCLEEAEMVRPGEHVTILTYSRMRYHVMQAAKTLVNKGYDPEVIDIRSLKPFDLHTIGNSIKKTHRVLIVEECMRTGGIGASLRSAIIDNFWDYLDAPIMCLSSQDVPTPYAATLEDATVVQPAQIVAAVEQICQ
The following text describes a protein:
Function:
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
Subcellular Localization:
Nucleus.
Sequence:
MKVQMLSRRVMQSLLRLQGCSCPSNSRVLSTSRVVLKSEHDKIDDEMKKITEKLGKEFEQSLKDGKTEPEIDKKFMNFKQLSEQKAHERSHIFTWKTVLGTFVVGGSMLLALFYIRKVRVEEAEKQRKLTAGKARIGGDWELQNTDGKLEGSEQLKGNWLLLYFGFTHCPDICPDEIEKMVKVVEQLERDKNPVKILPIFISVDPARDTLKRVKEYCAEFSPKLRGYSGTKEQVNKVAKTFRVYHSEGPKTAPHDYIVDHTVIMYLIDPQGNFHDYYGQNRRAEKRVMAKNPGNSEFVVKVPELNDMKRFTVLKFNNSIKIDPTTWANPECDIRMEREENRVLTSGLAAVQDFGEGTEYGKAAREEARRKKLGRRANQYSIDKQPWRMKINEADGKEKKLHSIREAAGTHADYWLFLKNGEEFHAYKVDDWHGFVPAITHKTLDIDEAEEEFTKRNRVMNQFALRAQILDKMKQKEADEEEEQKKGRKSGLMIKDEHSSSGSEGDDEKDEDGEEKKKKKVKKGAKPRKDKRVKVENSDEVAKYESEDGEDEGREYDYMSDSGSDSDRDIPMEDKVEKALVGVAEEEGLKKLMESDDSSEDDEDDPEKKLLNRKDDDDKKRRIDIEERDSSGSDSEVDDLDKDKLDSVILMPKKGGIMDGGAGTSTGIKRPADDTPKGPEVKKVKEEKEEGLTEEMVRKLLRTKPYTTKELLTKIKARCGGELPKAEMVTKLAAILKAIEPQQFKQKQGRKDVLFFSLSNTI
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MTTPGAGAMSAAAGSGGPDGNWRSTQFRSKVVAQINDALRDACNPIEKSGSELEEHIFNRARDRDSYLSLVARLILHMRDSNAAKEKGLTGRMTPNMAGQQQDPMVALQGLTQMGQSHSPGGPSLQMQPNPNQMVPGVGNQGNRPMMRNQMGQPQGGNLMDQRQQQQLQNLQKLMSNPSQPGGGGMAPGSGGMHQSQQAGQTQQSQQQPSQMPGHYQGGAVGGMQQTGFPGPPGGGGNMTPQPQTGGMPVGPQGGPNQMHGMQQQGGGQMGMPQNNMSQNNMMPQQQMNQMVRPQQNFQNTMVMQGQKPQAPIPPRAQVPRSYPVQSTPPIQSRAPMSPYGGYPYMMSPQSVVTDSPVYRQQPSPAQPTQQGSAPGSNAMHSPASYLQPSPSPQGLSIPSPASAGSQRGGPPSVPSPSSTLNTPGNPASVGSINPSPGGGMRGGPGSNQGQAELIAYQEKMRFLSKYIEPLKKTILANSNREESGGLSATDVNKMKGLLEIIANPNPNKRLTLQQLTKCEQYLEGFEQVRNQLATSNSTSAAGTSTTATSASATSTLDTRIMGKTNMFQPLLDAVKANIDSPYINHTLQRTFGPALTTLQGNPSHFPSPPAKKLKTEHDRSPTTQTAIPNIIQGEVARLAPKFRVNLDPMFHTSSKDVHLICRLDDKHLPSVPPINVAIPEQYPELSPNYDVSQQEYGQTPFLKLVQAALQNQVMRMPDRYTLTQILDAWEMSVRKSCLKMIAARDAT