lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Subcellular Localization:
Nucleus.
Sequence:
MSRGGWRKRAGEEDGWGGRGGYMAAKVCKLEEQFKADAPKQQQQQEGSCSSIFRGVAIYVNGYTVFRGADPTADELRRLMMLHGGQFHVYYSRSKTTHIIATKLPHSKIKELKGEKVVRPEWITDSIKAGHLLSHIQYQLYAKQKGLSFSSAVKVMECVADPGGSRRELENRVNGTARSVPDLVRDLRVNGTCGEPAAQRGQSPAEQPRDTPALANGHAGCHVPNGALKPPEPGLPPGSPAPPRPRPADCNADFRDAWGEPSDPRQPAPWHGGVRLNGTWHPAVQESSRPRSTSEASPGGTAAAPGAAHRPTEPGFISDFYSRSRLHHISTWKNEFTEFVNTLQRSSHGLLPGREKLRRQRSGRSADPGRAAGSSPAAPPRRQTCILHVDMDCFFVSVGIRHRPDLRGKPVAVTSNXNITRAPVTPPLGTEMVFTYAHENSLTPNPDWPLWMIWVSPPNVMKAKGVESRRGSAVFSNLTLDPFFRQAGVKNGMFFGQAKQLCPGLQAVPYDFHAYKEVALAMYETLARYHPFPTPLTADQGAGAACAFRNRANVGRHSMTAPLREVIRDSRLCRLSLHVIGSNILLARMATRRAKPNGQYYLKPEEVDDFIRDQLVTTLPGTWVRTPVRPFCKSLVPNGKPPNFTLGGGEWGEQTCVLKNAFGRSAVQARCQTELSPPKWSCGLTRRSVVAQLEEAESFLLNLAGELQRRLQAVGARGRRLTLKVMVRKPGAPLEPAKFGGHGICDNLARTVNLDQATDSARVLGSEVLKLFHSMKLNVSDMRGVGMQVQQLVPTTAVPSDSSCQATPRSRSIKDMLLAHRGVRHVLPDSAALDERTAPVRGLPPPSPTPEPEPGTSKWEPIPRYNGSLHATPLARTRLNLSIEIPSPSQIDRSVLEALPADMREQVEQTYRSRAEETPGSTVAEPQHLGTLVLQIPEQLAQGGAGGIIVALPDFSQVDPEVFAALPPDLQEELQMAYGQRQTTTQAVAVGQEKAVRPPVAKNSLLHLKQPAVKTKRRNKKNPASLAKKGQSPLKSRLLHSPAKGSPQKLLPDLLKHESPAKDRLKVLLEPLQPSGLFTAGRPSTSSLKPDPQEQLSKPVARPQPSLAGAIELPDIKVLLRQWVTTISDPMEEDILQVVKYCTDLIEDKDLEKLDLVIKYMKRLMQQSVDSVWNMAFDFILDNVQVVVQQIYGSTLKIS
The following text describes a protein:
Function:
As a component of the decapping complex, involved in the degradation of mRNAs. Promotes P-body formation. Translational repressor.
Subcellular Localization:
Cytoplasm, P-body.
Sequence:
MGRGRGPNTADSYIGSLISLTSKSEIRYEGILYTVDTENSNIALQNVRSFGTEGRKKDGPQIPASDKVYDYIIFRGSDIKDLQVKSSPPPPLQPPPPPQPADPAIISLQSQQQYPPPPSLGSYNGGHPAAGSSSEPSAPPSPYIRMPSQYPRAVPPLYPPAGLQSWGPPPPPGANGSGLAMPMYWQGYYRPPPAGHMQHQPIPPTSLAALPQGQPLLQQSPQQHGQQPVQQGQHASALPQPSLGVPHSSGGATVPDSSGEVTLSSQLQPQPSPSKAVTAAVAPLSSTTVNPTVSSVSTTTTPAALSSGTPASASASEVPISATFSLPLSLQGVSAVITPVAKNPRRIVGNLSQTPQISSSQTVGSSSQGSQSTSSAPSVSSGSLISPQNEAAQTSGIVATAAKRGTTVPQSQLVPDVELKPAEPANVERASSVQTSSQAAPPQEQLSQPLLPLPSVEQKQQQRGHHGVPVGQRSRWQVNGYTGNGNYTRRGRGRSSGSGRGIGLANPTQQFTEDFDFTAMNEKFNKDEVWGTLGGKDEEEEYEYDDGNAEVDVADSTQSDAPKKALYNKDDFFDSLSCDASGGRGERTKFSEQRKIDTETFGAFPMRSRGGRGGRRGGHRGGYFGGGSYGISRGSSYGRGRGMGRSASGHV
The following text describes a protein:
Function:
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of pyranonigrins, a family of antioxidative compounds. May be involved in the secretion of pyranonigrins (Probable).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSHDQRSPSEEVSRTALSKPASESTIVGDGHHPLPAKDTSTRAWLVVVGGLLIYFPTFGFLNAFGTFQTFYVQDLLAGTSSSKIAWIGSLQIFLLFIGGLVVGPLYDKVGATKLLVPGSVVYVVALMLTSVCKKYYQLILAQGILFGCANALLFYPTIAAINQWFDRRRGIALGLAVSGSSLGGIFWTEIIQLMLDHIGFGWTVRACGFISLAFLVPSCVLIITRPPEPGESKDMQLDFKAIFTDTKYLLFSVGMLLVLWGMFIPFFYLPSYGETYGMSVTGANNLLAYMNAGSFVGRVLTGLMADRLGRFNVISLAALSCGILLFCLHKITTSGAIIAFSTLYGICSGGLISLQSACIGQITPDHSIIGVKIGLMMGFCSVGGLTGSPIAGALLSADHQKWYGFIDFCGSILMGGAVVTILSRYVAAPREWKF
The following text describes a protein:
Function:
Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine. L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator. May also act on O-phospho-D-serine.
Sequence:
INEMDFCRTSRNIMTTLLETKELFCSADAVCFDVDSTVIKEEGIDELAKFCGVGDAVTEMTRKAMGGSMSFKTALTERLSIIRCSREQVNKLLTDHPPQLTPGIKELVGCLQQRGVKVFLISGGFRCLVEHVATQLGIPLDHVFANRLKFYFNGEYAGFDETQLTAESGGKGRVISFLKKKYELQKVVMIGDGATDLEACPPANAFIGFGGNVVRPQVKEKSAWYVTSFGELLKELEKN
The following text describes a protein:
Function:
Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion. Protects the gastrointestinal epithelium from irradiation-induced apoptosis. May play an important role in maintaining normal growth homeostasis in epithelial cells (By similarity). Involved in p53/TP53-dependent cell survival after DNA damage (By similarity).
Subcellular Localization:
Secreted. Endoplasmic reticulum.
Sequence:
MKRFLLATCLVAALLWEAGAAPAHQVPVKTKGKHVFPEQETEKVWDTRALEPLEKDNQLGPLLPEPKQKPAAAEEKRPDAMTWVETEDILSHLRSPLQGPELDLDSIDHPMSDDVQDEEVPQSRPILYRQVLQGPEEDLDHLAHSMEDS
The following text describes a protein:
Function:
A minor shell protein of the bacterial microcompartment (BMC) dedicated to 1,2-propanediol (1,2-PD) degradation. The isolated BMC shell component protein ratio for J:A:B':B:K:T:U is approximately 15:10:7:6:1:1:2. Not required for structural integrity of BMCs nor to mitigate propionaldehyde toxicity, it might be involved in spatial organization of BMCs; The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
Miscellaneous:
MISCELLANEOUS: Bacterial microcompartments (BMC) 100-200 nm in cross section are formed during aerobic growth on minimal 1,2-PD-B12 or anaerobic growth on 1,2-PD-tetrathionate medium, but not during aerobic growth on glucose, anerobic growth on glucose or pyruvate-tetrathionate. BMCs can constitute up to 10% of total cell protein.
Subcellular Localization:
Bacterial microcompartment.
Sequence:
MANKEHRVKQSLGLLEVCGLALAISCADIMAKSASITLLALEKTNGSGWMVIKITGDVASVQAAITTGAHFAEQWNGLVAHKVIARPGEGILLAETPSPSVIEPEPEASEIADVVSEAPAEEAPQESELVSCNLCLDPKCPRQKGEPRTLCIHSGKRGEA
The following text describes a protein:
Function:
May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTKISVGLQLVTRDSREKLNNIVIKSSLRLNRSNPNISELCFLKTCHLCNKQLHQDKDVYMYRGDLGFCSRECRESQMLIDDRKELEASTKMMLASYRRCNNGAGKSESRNLFDDLRRRRQLFIVP
The following text describes a protein:
Function:
Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MADQETAQSPIEEPSESAAQAAAETLADAEIPATDAAADASEGVVDDIDVIPPSDPEHLTTVVRGQDTAAAVRTAAIFDEDDEDEDDDGDEVGNDLPSFRKRDARDASNADDPDAAVMRKKKKKRHHSPEEASSMRHVTDGEVEQEEEDPYANMTEAEIRRARTDRMIDEALRAGKKKAPRKRAGEDDLDLLADEEVAALRREMVTAADDDEEANRLKKPATNKLKLLPKVVATLQKNHLQQSILDNNLLEGVKRWLEPLPDKSLPALNIQHQFFQILERMTIDTISLKMSGLGKVVVFYSMCSRVEPKIKRSAEHLIEVWSRPVLKRSSSYRDRHIASAEWNREALSQRAGPLVVGSVADNNRRNVGIPQAVTAGFRVAPQSVAGQRSDSGHEARMANHKRLNQFKSRLKEAKR
The following text describes a protein:
Function:
Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process.
Subcellular Localization:
Nucleus.
Sequence:
MAADSLRQHHQAGNWGDDPKTMQDLTSVMQALLQQIQDKFQTISDQTIGRTDDTMSSWITGRTDDMRSRIGDLDKNTIDLMTQAGVKELDGENKTPAPQRSWSLLMRTRLCSILFMSQEKMEDGWLFATNYYV
The following text describes a protein:
Function:
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Sequence:
MQVKHLLLIAILALTAACSSNKETVDENLSESQLYQQAQDDLNNKSYNSAVTKLKALESRYPFGRYAEQAQLELIYANYKNMEPEAARAAAERFIRLHPQHPNVDYAYYLKGLSSFDQDRGLLARFLPLDMTKRDPGAARDSFNEFAQLTSRFPNSRYAPDAKARMVYLRNLLAAYEVHVGHYYLKRQAYVAAANRGRYVVENFQETPAVGDGLAIMVEAYRRLGLDDLASTSLETLKLNYPDNASLKDGEFVARESEADTRSWLAKATLGLIEGGEPPPHMETQAAKDVIKQYEDAEREIPAELKPENQDHSADDEKPESDDDEDSGRSWWSYMTFGLFD
The following text describes a protein:
Function:
Probable methyltransferase required to silence rDNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTDINNNKYSKLKVKKNKNKKNNNKNNDKNNTLLVSPNDKLKKEKRKKKHKNLNQKVIHNNNNNNNIHKDEHINEQSNNHIYVNNRTKKKKKNIELIKDKWINKKKKKKTKKKTKKKTNNTTIYDNDNNINVDEEEEKKKKNVFPYISVLRENVVNNKIHIHDTNEAYKYDYADLENNKQKYKKKKKIENSPEDIVNSSLFRYINEYMYTNNSEVVQNKLNQTKNVFNIYHQGYKNQKNKWPHNPVSIIIKHLKKYFNKNNKIADLGCGEAEIARTLDGWYIKSFDLIQYNHYVTPCNITQLPLNNNSYDCFILSLSLMNTDWPKIIFESVRCLKKGATLIIAEVVSRFTNYKAFIKFMNNVGFKLSNKINLDDFFYVFFFEKNQEVDISSSINEKRIKKVSSLLTPCIYKRR
The following text describes a protein:
Function:
Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region.
Domain:
Both bilin lyase domains bind with the bilin tetrapyrrole chromophore precursor. The domain 1 shows red, far-red light photoreversibility. The domain 2 is photochemically inactive.
Sequence:
MNPNRSLEDFLRNVINKFHRALTLRETLQVIVEEARIFLGVDRVKIYKFASDGSGEVLAEAVNRAALPSLLGLHFPVEDIPPQAREELGNQRKMIAVDVAHRRKKSHELSGRISPTEHSNGHYTTVDSCHIQYLLAMGVLSSLTVPVMQDQQLWGIMAVHHSKPRRFTEQEWETMALLSKEVSLAITQSQLSRQVHQQQVQEALVQRLETTVAQYGDRPETWQYALETVGQAVEADGAVLYIAPDLTGSVAQHYQWNLRFDWGNWLETSLWQELMRGQPSAAMEPMAAVQSTWEKPRPFTSVAPLPPTNCVPHGYTLGELEQRSDWIAPPESLSAENFQSFLIVPLAADQQWVGSLILLRKEKSLVKHWAGKRGIDRRNILPRLSFEAWEETQKLVPTWNRSERKLAQVASTQLYMAITQQFVTRLITQQTAYDPLTQLPNWIIFNRQLTLALLDALYEGKMVGVLVIAMDRFKRINESFGHKTGDGLLQEVADRLNQKLSPLAAYSPLLSRWHGDGFTILLTQISDNQEMIPLCERLLSTFQEPFFLQGQPIYLTASMGISTAPYDGETAESLLKFAEIALTRAKCQGKNTYQFYRPQDSAPMLDRLTLESDLRQALTNQEFVLYFQPQVALDTGKLLGVEALVRWQHPRLGQVAPDVFIPLAEELGLINHLGQWVLETACATHQHFFRETGRRLRMAVNISARQFQDEKWLNSVLECLKRTGMPPEDLELEITESLMMEDIKGTVVLLHRLREEGVQVAIDDFGTGYSSLSILKQLPIHRLKIDKSFVNDLLNEGADTAIIQYVIDLANGLNLETVAEGIESEAQLQRLQKMGCHLGQGYFLTRPLPAEAMMTYLYYPQILDFGPTPPLPKVALPETETEAGQGNVGDRPLPNSLNRENPWTEKLHDYVLLKERLQQRNVKEKLVLKIANKIRASLNINDILYSTVTEVRQFLNTDRVVLFKFNSQWSGQVVTESHNDFCRSIINDEIDDPCFKGHYLRLYREGRVRAVSDIEKADLADCHKELLRHYQVKANLVVPVVFNENLWGLLIAHECKTPRYWQEEDLQLLMELATQVAIAIHQGELYEQLETANIRLQQISSLDALTQVGNRYLFDSTLEREWQRLQRIREPLALLLCDVDFFKGFNDNYGHPAGDRCLKKIADAMAKVAKRPTDLVARYGGEEFAIILSETSLEGAINVTEALQVEVANLAIPHTVSGTGHVTLSIGIAVYTPERHINPNALVKAADLALYEAKAKGRNQWLAYEGSQLPHVDGEV
The following text describes a protein:
Function:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MEFLVPLHAADLELPKAGRYHVQSVLTFEGETPAELSARVQRLEDHVLGSDAGLELLRAEWLDLTYSLVKKLPGLSEPLRMRVVEALAAFVANATEGVLARRPGSDADDVAQYRSAFKASVYFLITALTSVSNAQLQADKDVVKHKRKASATSALNRVNWSKVVEGAIQKLSRSVSPATFSMWNMNVPEEEFSMLYCKAVFELLGNASLCRGKTLKPKLYHLLAMGLQKAPAIHISVVASLIDLIYTHEHLSASIAELVELLYFKYANVTFAADLINEIGKISSRDASKDVAGTRNISMFLSSLSTLTPALIMGNLSFVLALLDSEAYQLRNAAVTCVTQILLWNFRQSGHQDPQTSSADSAASKKKMRKRKKTDGETKSDGSESEDSTADEDASSSSDSNDEEDAGKTSAEAPRTFSRSTRDQLLTVLEDRTHDVNSFARSHVLKMWALLCEEGALPLHMLKNVTLMAVGRLQDKAAVVRRHSIHLLSLLLERNPFMGNLNRDFYAKKRDELTEEMKKKRDEVIAGAEKEMSEALGEIAIQNGGDAESSALSQPAISSEEQAAALEKELQTTVRLLKFYQDAIDFIDEFELQALPLMAQLLGSKSISDVLEAIQFFEKAYRFHLGAAQTGIKKVLPLTWRSDVSIQEQLSNTFVALFIRIDEEDPERNSPQLVAENLVKFLDECTVAEYTCLERIMGELHRSQKVPMVVISSLWGLVDVTVYPISIVSNALVLLSMIASIDDSMLFSNDRLGQVLSMGFGDVACSPDSRFRVLGAACRLVQCIQLEPKNAAARSSSQTQRRIQRSNLDATEQIILCLQRFLALDFVGDDTIELECLHSTWFDIVQQAIEAIFSICERPEDVCGDVIKHLSLRLFESETNDVSRVELAHFFFVLGHSAVKVAIHVEKLAAKVKKMRFNRNSAAKPADNTASNGDAEDVTAMEDELGVAAEVEAEEDTFVNNVIQKEIACRNLLGLYSPLIIRVLVGKEEEFKGDELLTECAVVALSKFMAVSEEFCEKHLQLLFTILQNSPQPSVRGDVIIALGDLSFRFPNLVEPWTSHLYNRLRDVNLNVRKNTIVVLSHLILNDMIKVKGQVSEIAISLVDENDGIRNLAKLFFFELSKKGNNPIYNMLPDAIGQLSTSELVSNPEFQTITQFLIQFIAKEKQIESIVEKLAQRFPTASKAQQQRDLAYCLARLPHTEKSLKYLYQNRKLFSDALHDAAVADHFTSLVAKARRGNSALSATAEMKEAIDTLDQFVVGKKEGKEEDETMDGETKERVSSPQAKGRAKRKAVGKGAKATRAMPKKRERAKRRTRKQKATRAVSDDSSEEE
The following text describes a protein:
Function:
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MKFLAVLLAAGMLAFLGAVICIIASVPLAASPARALPGGTDNASAASAAGAPGPQRSLSALQGAGGSAGPSVLPGEPAASVFPPPPGPLLSRFLCTPLAAACPSGAEQGDAAGERAELLLLQSTAEQLRQTALQQEARIRADRDTIRELTGKLGRCESGLPRGLQDAGPRRDTMADGAWDSPALLVELENAVRALRDRIERIEQELPARGNLSSSAPAPAVPTALHSKMDELEGQLLAKVLALEKERAALSHGSHQQRQEVEKELDALQGRVAELEHGSSAYSPPDAFKVSIPIRNNYMYARVRKAVPELYAFTACMWLRSRSGGSGQGTPFSYSVPGQANEIVLLEAGLEPMELLINDKVAQLPLSLKDSNWHHICIAWTTRDGLWSAYQDGELRGSGENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANCTGPLMGNVLPWEDKLVEAFGGAKKAAFDVCKRRAKA
The following text describes a protein:
Function:
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Also promotes differentiation and proliferation of hematopoietic cells (By similarity).
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Domain:
The kinase domain is involved in SPSB1 binding; The beta-propeller Sema domain mediates binding to HGF.
Sequence:
MKAPTVLAPGILVLLFTLVQKSNGECREALAKSEMNVNMKYQLPNFTAETPIQNVVLHKHHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCVPCQNCSSKANLSGSAWRDNINMALLVDTYYDDQLISCGSVNRGTCQRHVFPPHNTADIQSEVRCMYSPQPEEEPSQCPDCVVSALGTKVLLTVKDRFINFFVGNTINSSYLPDHSLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETLDSQTFHTRIIRFCSVDSGLHSYMEMPLECILTEKRRKRSTRQEVFNILQAAYVSKPGAHLAKQIGASPNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSVLPAPHVNFLLDSNPVSLEALVEDPVNQNGYTLVVTGKKITRIPLDGLGCGHFQSCSQCLSAPPFVQCGWCQDKCVQVEECPNGTWTQEICLPTVYEVFPTSAPLEGGTMLTICGWDFGFRRNNKFDLKKTRVLVGNESCTLTLSESTTNTLKCTVGHAMNENFNMSIIISNGRRTVHYNAFSYVDPIITSIFPKYGPKAGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQIISTEFPIKLKIDLANREASSFSYREDPIVYEIHPTKSFLSGGSTITGVGKNLNSVSVTRMVINVHEARKNFTVACQHRSNSEIMCCTTPSLQQLNLQLPLKTRAFFVLDGIYSNYFDLIYVHNPVFKPFEKPVMISMGRENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSRSQAVLCTVPNDLLKLNSVLYIEWKQAVSSYILGKVIVQSDQSFTGVIVGVVAISIILLLLLGLFLWLKKKKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLMDLSPILTSGDSDISSPLLQNVVHIDLSALNPELVQEVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDRLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCIAPYPSLLSQDDLDGEVDT
The following text describes a protein:
Function:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Sequence:
MQEEFDWPTLVLSTSPETENVTSSSVRSTTKNDVVIQQGSISSYWPWDVMKLENDTHFLSHSSGDGMKCTKADHFLSHANRGSLNLDYQEQPSKSNFATDLGSHAYSKEARTLGRVYHGQQPYFSPSSCSWEKSSALKVVPNSPDASGHIVGEMRTKTNILSARSNYLSYPTDVPHIRYRDEVKVDLSQDDNSKQYRRPDQFTAFSNFNGQSSEHLETAKGANYMDEITPISRQWCFDNRGPSLPRGLVYGDEIPSLSSKKCNGNVASSYSRIWDYSAETTSVRQCYGDKIPSLSHHWHYRDKIPLHSGQWCHDAEARPLSNYQQGASYGNGRLRDNISRGGRNEQVNIISSRRTMTKPRVANKVVSSTDHYKINKDNLWRNSEDIRDQVRGPRANKLNNSSTSSIKNNAIPPLVCRDQINRPEFTVQYEHAKFFMIKSYSEDDVHKGIKYNVWASTPNGNNKLDAAFHEAQILMKEQGKRCPIFLFFSVNTSGQFVGLAEMLGPVDFKKTMDFWQQDKWNGFFPVMWHIIKDIPNRFFKHITLENNEGKVVTFSRDTQEIGLPQGLEMLKIFKAYHQGTSILDDFYFYEEKENMRHAQKGRNLETTNQDLFSDDFRSISVENLEASMQSLSFYETWE
The following text describes a protein:
Function:
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MAVLWRLSAVCAAQGGPALLLRTPVVRPAHISVFLQDRPIPEWCGVQHIHLSPSHHSGSKAAERVVSVLLLGLLPAAYLNPCSATDYSLAAALTLHGHWGLGQVVTDYVHGDASQKAAKAGLLALSALTFAGLCYFNYHDVGICKAVAMLWKL
The following text describes a protein:
Function:
Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Peroxisome.
Sequence:
MKRISATELQGNVLKLPRLPIPSVAATMDGYRSSLRALWSPEVTAPHLAKLDAFVNSSAPVLQRHLVDADMAAAESGKAPFTYVEGLLAQSALKSRSPQEVNMNASFVLQQDIAGADRTQAGVASALTYGIACWIQELRTNGLSVPADPAAQYDVSPLLTEFGRSLIPSKETDLLHTTPLEKLSHIIVLHDGHPYMVRVFDEHQRVLDRRLIQKAFELILTITPDQDNTSPVSVLTAGSRAVWGQAYQELLKTPENAEVLRLFHESILVVCLDSMKWGNDESLAEASALHGSKEELENRWYDKHQMIVSEDGQVAFNFDSTASDRVHWAKWIGDVLSILKERGVSGGSTDDIDGAAVSRIVRHLSVTYGKSFVSHIRAARQEALAIVTDTEVHSIHLPCGRAQLSALKVKPDAFVQMCLQLAMYKMRNKLYSTTEVCSTAGFFHGTTELVHTTSEEMLALAKNLAQLQQDGEHAAALDTNGKEMLTKLIRATSDRHVALTAAASRGEGYDRHLMALRHVARINGDKAALAFFEDDLFLKTSRSVLSTSEFSQSWLRYYTFGPMQSNGYGLGYVIDEQEVRISLSAFTNSPTTNVADLKAALMLSCNTLCEVLGGVPAANTAAAEAPK
The following text describes a protein:
Function:
Potential transcriptional activator of carnitine metabolism.
Sequence:
MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNTLTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSREKLVGVRKTPRIPAVPLTELNREQKWQMMLSKSMRR
The following text describes a protein:
Function:
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).
Miscellaneous:
MISCELLANEOUS: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils, whereas prokaryotic enzymes relax only negative supercoils.
Sequence:
MNSIQVKNEPMLASFASTSTNGKAKRSAKPSLFSGSEVSSDDDEEKPLAKRPKVEDSDSDAPLTSTVSSQNGVQKRSGSSNNDDNDDDSDSDSDAPLTALVKKSNGSDDDEDDDDDDDEGDDDDEEDDDDDDDDDDKPLSKSSKSNRKPPKTMSITGSGEKKWDVLIHKGPRFPDPYQPLPKDVKLKYDGRPVDLPWQTEEIAMFYAVKLETQHAQNAIFNRNFFDDFKTDLKKYPPRDGTQIKSFDKLDFRDMYNYWRSLKDAELERKKALAPSARKREIEERKAEETKWKICLVDGVEQRVGNVNVEPPGLFLGRGAHPKAGKVKRRISPGDITINHSADHPAPQPPAGMGDWAEVVEKKDVTWLAYWKENINGQYKYVFLDATSNFKTNSDREKFEKARKLDTVVKQIRRDVNKNLKSKVRHERQIATIVWLIDNFSLRAGNEKGEDEAETYGVCSLRCEHAQIKMPDTIHLEFLGKDSMKFEEDLKITNPDVFKNIAMFLKSNGMKDKSGNYVRKKPSDPIFCAPESGSGKMQPLQPNSVNQFLSKYMKGLSAKVFRTYNASVTFQGLLEQTEEWLKSRPNAAEREINQTNLRLAYNEANRQVAILCNHQKTVNPMLLNRNLERTQDKIFQIRYEIMKEQQKILTFHKVSELKKEFKVKEHPFMKQFDKIMQKQDLDAEKVKQYEEQMISDKKSKLESTFKRQQSELQYQLEQKGLTGDDGTPKKGKKAKNVEEEVRSSIKGFKDKKQVDEELKALNETAKRLEKERKTNKSQATSCNFVSSAKKILSKYEMIKKQEAELVNKNNTSDVALSTSKLNYIDPRITLAWLKEWDDRLSDLGQGKAAPKKKVKKEEEENDIKPKKKDAKGAASKKRAAKTGLANSTGDSEKMELGLQVMNISQFFANALQKKFKWAASGDDGRDISAKWVFVKDAQSKMRKLDSAERKGQKGGSMAAMTDAADSKEAQPKVNCVLKKQTSADRKMSKPIKAVDKTEESDDDLSSDSSDDEDKPLAAVV
The following text describes a protein:
Function:
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
Sequence:
MAAPAQKFKVADISLAAFGRREIELAEIEMPGLMAIRRKYAEDQPLKGARIAGCLHMTIQTAVLIETLTALGAEVTWTSCNIFSTQDHAAAAIAASGVPVFAWKGETEEEYQWCLEQQLNAFKDGQKLNLILDDGGDLTALVHSKYPEMLKGCYGVSEETTTGVHHLYRMLKEGKLLVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCADALRSMGARVLVTEIDPINALQAAVQGYQVVTMEEAAPQGQIFVTTTGCRDILVGKHFEVMRNDAIVCNIGHFDIEIDVAWLKANAKSVQNIKPQVDRYLMPNGRHIILLAEGRLVNLGCATGHSSFVMSCSFSNQVLAQIALFKAEDEAFGKKYVEFGTTGKKPVGVYVLPKILDEQVALLHLEHVNAKLSKLTPVQAEYLGLDIAGPFKSDM
The following text describes a protein:
Function:
Probable phosphatase.
Sequence:
DDKARELLRDFDPYLFIKHLPDPSLVLSPCRKFLLPRRTRRCPPVALVLDLDETLVHSTTDHCGNADFSFSLHANFQRQTVYVRRRPHLQMFMERVAQLFEIIVFTASQSTYAEKLLNILDPKRKVFRHRIFRDSCVLVDGNYLKDLSVLGRDLSKTVIVDNSPQAFGFQVDNGIPIESWFDDEADCALASLLPFLESLASAEDVRPIIASTYKLRQKIQAASDPPWLRHCVHENEKQAQ
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Functions with WRKY25 and WRKY33 as positive regulator of plant thermotolerance by partially participating in ethylene-response signal transduction pathway.
Subcellular Localization:
Nucleus.
Sequence:
MGSFDRQRAVPKFKTATPSPLPLSPSPYFTMPPGLTPADFLDSPLLFTSSNILPSPTTGTFPAQSLNYNNNGLLIDKNEIKYEDTTPPLFLPSMVTQPLPQLDLFKSEIMSSNKTSDDGYNWRKYGQKQVKGSENPRSYFKCTYPNCLTKKKVETSLVKGQMIEIVYKGSHNHPKPQSTKRSSSTAIAAHQNSSNGDGKDIGEDETEAKRWKREENVKEPRVVVQTTSDIDILDDGYRWRKYGQKVVKGNPNPRSYYKCTFTGCFVRKHVERAFQDPKSVITTYEGKHKHQIPTPRRGPVLRLLGKTET
The following text describes a protein:
Function:
Chaperone essential for folding and oligomerization of both long and short tail fibers. Required for the assembly of gp34, gp36 and gp37 (components of the long tail fiber) and p12 (the subunit of the short tail fiber). Together with gp38, participates in the formation of the distal part of the long fibers.
Sequence:
MSEQTVEQKLSAEIVTLKSRILDTQDQAARLMEESKILQGTLAEIARAVGITGDTIKVEEIVEAVKNLTAESADEAKDEE