lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Sensor kinase that senses the plastoquinone (PQ) redox state involved in stoichiometry adjustment of both photosystems (e.g. long-term adaptation via transcriptional regulation of reaction center genes of photosystems I and II) and state transitions (e.g. short-term adaptation involving reversible post-translational phosphorylation of light-harvesting complex II, LHC II), thus linking photosynthesis with gene expression in chloroplasts. Autophosphorylates, probably on a tyrosine residue. Probably phosphorylates SIGA/SIG1 in response to plastoquinone redox state modification. Reduced PQ suppresses its autophosphorylation activity. Represses expression of a number of chloroplast-encoded genes.
Subcellular Localization:
Plastid, chloroplast stroma. Note=Associates with thylakoid membranes.
Sequence:
MLLSAIASQTLLSSNPNLHFSNSIPNPRPSNPSLKLLNASSSSSSSSSSSIFTRGLRYVNHTVSNEESEPGGGETMVASASAIASAIRGASTTPVEFTQMIEKDHLKTKIILPSPDFQRLCLEQLDLFRQIVDPNAVLSIYVRPAGSYVMDRLELRRVTCYPSVNAGDVVILVGNFGIPAGLRAAEASLSSQQVELVSKHRAAVFPMVKHPFVVGFLVAELPVEAEEEEEEEEEEKPHGVNQFLSPEEAYALPASANTKSPRVKLPSVKVFTEEQRSYAINISRTLAMAYVMDQKTMLLQQSSWQNNVRMSKLVEQIRGPLSTMRTLSKMLSTHTKRNQISHDIVEDLIVQGDQIKDTLEELQDAVHLTKANIVRHNEEALKKINKTHNETRRSKYEHKDPIDGSQISSTRLSLGSGLDDSEMPMPPLALAPLQMHSIRPCDISNVLLDMVETVRPLALTQQRVVELGENSASLQVAVEEPALRQALSNLIEGALLRTHVGGKVEILSTRAPAGGSLVVIDDDGPDMRYMTQMHSLTPFGAELLSENMVEDNMTWNFVAGLTVAREILESYGCVIRVISPRSSDAALGAGGTRVELWLPAFPAAVSEANEA
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDQQNGLFGFLENHVMEPMGKLAQFKVVRAITAAGMAAVPFTIVGSMFLVFSILPQAFSFWPIVADIFSASFGKFTSLYMVANYATMGSLSLYFVLSLAYELTKIYAEEEELNMNPLNGSLLALMAFVMTVPQIIFDGGMMKAVTSLKEGAVIADGWAMGNGVARFGTTGIFTAIIMAIVTVLIYRMCVKNNWVIKMPEAVPEGVSRGFTALIPGFVVAFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGANIVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQLKAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPIIAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI
The following text describes a protein:
Function:
Functions as an E3 ubiquitin-protein ligase. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate.
Miscellaneous:
MISCELLANEOUS: Present with 195 molecules/cell in log phase SD medium.
Subcellular Localization:
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Domain:
The FYVE domain mediates phosphatidylinositol 3-phosphate binding and is necessary and sufficient for targeting to endosome and vacuole membranes.
Sequence:
MVIKEDCINNLARWQADEEAHSCFQCKTNFSFLVRRHHCRCCGRIFCSSCTENFVNYNKKRVHALQKKNSDVESPPYRTCNECYDNLLHLNLLVSSTNRDVRLSQTSVPPNALALSAPDSNTDEDAEILEDSVDQSGTACRSEESSQNEEDHFCPICNSDLTQFPDEEETRKHVEDCIQRAENAQQHTNTSDAADDSVKESPAFQNRMLVYKISPNTTDNAIKECPICFENMEPGEKVGRLECLCVFHYKCIKNWFHKRAQMTAAQKGNGHAFVKRNFCPFHDAVF
The following text describes a protein:
Function:
Acts as a molecular chaperone for neuroendocrine convertase amon/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive amon in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated (By similarity). Also required for cleavage of amon.
Subcellular Localization:
Secreted.
Sequence:
MLFRSQTHVFPGVYMMVAMLVVALSGYQVQSYSAKDILADVLMTDLLNRMDKDMQVGYYDVGNEAAAGSKDNVDLVSRSEYARLCDGGSDCILQSGSASGAASHPSLRDDEFLQHSSLWGHQFISGGMGEGPNRYPTIVKNDAGLPAYCNPPNPCPEGYDMETQGGSCIVDFENTAIFSREFQAAQDCTCDNEHMFDCSEQDSADVGGDKGDLNSAVEQYIMQMGQENSLNNVNSLAKKAGYPVMPDPRLDDAVINPFLQGDRLPIAAKKGNLLFH
The following text describes a protein:
Function:
Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity).
Subcellular Localization:
Membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton.
Sequence:
MDNNNNNFSTPKQPTINSTTGGQLRSRSNSSPSTSSISTPRNGSTTATTSSITNSIGKGSLVFSTMENAKKTLNMDSLSTPMSQSSKKRLSMNSSLLPPSSIPLPPSQQLSAKKDPSKRHSSFISTTTTTSLGSRPSTPQPNHTTNNNNNNNNGSNGNNVTSTNISSMLESNNSEILSQNQKVTLSTSSNTAFSSLPSSTNNGNNPLSNSGGGNGNHHLVNSNSSTSTPSPTMFISTTSPPPELSLMEGFNQHNLTTTTTTTTTTTNNTLNTSNGINSNSLSPSSHLNNGSNNNNNNNHLNLNNRSSSPSPTPSSSSISGRRTPIQNFNSVGGVNITSKTQPLFSDREESIQAVCRFRPETAAEQTLGPSEKQLTIGTDQTTIHITPTSSSSSSMAQAFRFSKVYQPNTTQESFYNEVGKPLIDNIVNGYNVGIIAYGQTGAGKTFSLGFSGGEGNDSYNSYCNRSEFYNNSHYLYGSQQQQQQQQLLPSSWGIMPRIIKDLFIKQDEQQSMNTPQRIKFTTKISYLEVYKEKVYDLLSEGGVNDIEIRMADGGFIVPDAVQSSIQTFTDFLTHLQHIEKNRKIAETKKNMASSRSHAIFIVSLLKEDLENKMTVTSLLYLVDLAGSESASKIDGTTSKIEETKSINKSLYALGGVIEDMSKNSKHVRYRDSKLTQLLQQCFGGNSKTCLIVNCSSSNHESVIRETIQSLNFGQRAQSVKNKPLQNVEESHSELKAKLRELNKDIETYKKFIEKISINSGVIPPSSVATYITQLQNACEELKKKNDRLQEDIINLEEENSDLPKKFNVLNKNNVSQIEILTQELELSKQINQEQLLKIEQYSQKYQATNEEIQKSFNHRQQLVNDLHDSNEKSKQLELKLKDALLNSKSESDEIRLKLTKALEESTDKDQRINTLESNKQKWKSKCNEVVRQSKELQDRLNILQSTYSNSVDSLSNSSLNNNNNESLEEIKKLKLNISSLTNQHIEREKSLQKEIDLARSKHTEQTLILKNLKTQIDTLTNKLEIQFPTIVNNNQQQQQSTQSSSSSSIESNLIISMNTIEVLFEKICKNQEQTNTIISTNVESIMGKLVEIDENEEFIRKEKDRERERAENLKNTLEDAQSNFLKQQEEIKQFIETQLKNKNNINNNNNIKNNNNNNKLKSKKVGSSSSSSSNIGSSICINILFFLIILVILFFLMVAVGLTIQNQDYNSQYRSSYFFKTT
The following text describes a protein:
Function:
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
Subcellular Localization:
Nucleus speckle. Cytoplasm. Nucleus.
Sequence:
PMNAFMVWSCGERRKLAQQNPSMQNTEISKQLGYRWKSLTEAEKRPFFQEAQRLKTL
The following text describes a protein:
Function:
Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I-1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F-6-P)) and AMP in vitro, but this might not be significant in vivo. Glucose-1-phosphate (G-1-P), p-nitrophenyl phosphate (pNPP), and beta-glycerol phosphate (beta-GP) are also good substrates, compared to I-1-P. With much lower efficiency, can also hydrolyze inositol 2-phosphate (I-2-P) and glucose-6-phosphate (G-6-P) in vitro, but not fructose-6-phosphate (F-6-P) and trehalose-6-phosphate (T-6-P).
Sequence:
MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNGQPEITDAAVALPARGNVVYRTDTVTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPDLLMCRAEVAPILLGAIADAWR
The following text describes a protein:
Function:
Transcription factor involved in the regulation of hyphal growth.
Miscellaneous:
MISCELLANEOUS: Targets a different set of genes than S.cerevisiae ADR1.
Subcellular Localization:
Nucleus.
Sequence:
MISPTHQSQYLNYFVNPVLMTESGDIIDSVTGTTTTTANMSNTTIDAPTPASTTKNYKHKKQNTNTGTSMSPSNSINSTNNNAAAAAATTTTSKKSKDIPLELTAFGTTPSGKPRLFVCQVCTRAFARLEHLRRHERSHTKEKPFSCGVCQRKFSRRDLLLRHAQKLHAGCTDAITRLRRKSIKKSQDGDDDDDDDDDDEEMANSEDENDHDESGNASTKNGKKDKKDPPPEFNLNLFNSKQKPTKANTTKSKVAKLSTTTSRKNSTNPTRKNSSSLHKQVLDQRQKAAVNTKIVSSTKIVSGTNSGVSITPTRSRRGASFSAQSGANYAINIPEFNDIYPQSDNVEFSTPQFLPSSLDNEMTWLNNIPNIPGLSDSVSAANLMRQNSITNSADHVTPPVNVSQHGSFSHQSTFSATDMGQTRSESVNSLNTPFDGSYMMPTVTISNQEIQNGVAAHHHHQQQQQHQQHNHQHQPNQSSLGLSRNDMLSEDHYGYSFYDIPENILNFPMDSISTTSNAMSSGPIQNFKPLSPITQEIEHEITPRIDGRIGDFQNNNNTNDNPIHQNINYDLNFLHTIDDIGQDVISKFMPGGYSFYGDNNVSATSSANDYNSPNNIVSPSQQNNQFALHNQSSHPSGASPHLNQAMMNKMRLHNYSSNKLFTNHIRHMINKALGKYPISGIMTPTIPSNEKLEFYLSVFIQSFLAHLPFIHPSKLNEYEIMAMTGNEDINNESARVCLPLLTATMGALLANNKNDAEHLYEASRRTIHIYLESRKTNSTNDKNYKNGKDKSSSGNPLWLLQSLMLSVLYGLFSDNENNVYIVIRQLNALNSLVKTSIKNKGPIFFSNNGEDEELYNKLNSHDNGTSLFSNNLNDEMRYKNNINMQSQTRIVFIIYRLTNFLLMMYNVPLTFSINDINQLAVTSKDEETLWNFKNYQEFQEFSHKNNKTLDDYLNHKNEPIIFRELLLTVIKFGISDSNISPEIEKKVTHQLQNLCKYGFNCLVHGIYEIKQYQEMKEVDTFKVLDYLTKFYPTNDGLGFNCFRLPANKDLEKIDYALLVDFTKISSIIDLKLLKEQSWLKNYQDLTQNYHRLLDAHSTGNPLNSINDYDYLKLADCCISVLKLILFKVEDSNSNSRNRSKNDPTNEINNKLNNNNNNNNDMNNNNSNGDQLISAFDTDFGYLNMDNNGYAKKEEFSRFTDDELRYDKENTMSYFDKHIKLDIFEEVEKSSNLIQAQMLFHAFSVLSIFSVYVMRKNDNNSSPFANTDLIFELNHRYSMVLRLLERLETFLKLRYQTSAGGGGGGVNNNNNNALSIKLEQEFTNLYLYNGNVLSSDHNTNTNTTNTITTTTTTDNGTKQNQHHSQDFGLEKTLYILKMGENVLNYIYDLNLKVCVFKKLGDSLSEIRKYLIDNESTLNG
The following text describes a protein:
Function:
Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate. Shows weak activity towards deoxyuridine and thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (Probable).
Subcellular Localization:
Cytoplasm.
Sequence:
MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL
The following text describes a protein:
Function:
Stress protein produced under hyperthermal stress conditions. Serves as a glutamine and lysine donor substrate for transglutaminase. Inhibits the cysteine proteases papain and bromelain as well as the bovine serine protease trypsin. Has hardly any or no effect on subtilisin, bovine chymotrypsin, proteinase K from T.album, transglutaminase-activating metalloproteinase (TAMEP) from S.mobaraensis, dispase from B.polymyxa, thermolysin from B.thermoproteolyticus or collagenase from C.histolyticum.
Subcellular Localization:
Secreted.
Sequence:
MREFRRVRRVRFAACALVAAATGITLAAGPASADIPIGQKMTGKMTYYTDKGYGACGTPIDASSQDLVAIPAAWWTTPNPNNDPLCRGVSVEVSYNGRTIRVPVRDKCPSCDRTHIDLSQAAFAKLAPLDRGVVNGITWKFVR
The following text describes a protein:
Function:
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
Subcellular Localization:
Nucleus.
Sequence:
MQTENPPRPRQTRSLLTMDRCKHIEQLQLAQGHSILNPQKWFCMVCNTTESIWACLSCSHVACGQYIQEHALKHFEESSHPVAFEVNDMYVFCYLCNDYVLNDNTAGDLKSLRSTLSAIKGKSYPCVVQSDSVLQPVNAQADSYSLHDSTQSLPGSEDPMCTALWHRRRALMGKTFRTWFEQSPIGRKRQEQTQEKTVAKREVKRRQQELEQQMKAELECTPPRKSLRLQGLSEAATVEILPVQAPPPPPASPAKEKALALPPSEDGKLKRVSDSLIKRRPAVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAVAASDKARSYKHSAVTDAATAAAHQLNEGQEKEKGFACSRHPGLSSGLSGGASKGRNMELIQPREPSSPYSSLCHELHTLFQVMWSGEWALVSPFAMLHSVWKLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTKLPALIPTSQRRLIEQVLNVVNNIFHGQLLSQVTCLACNNKSNTIEPFWDLSLEFPERYQCSGKDAASQPCLVTDMLGKFTETEALEGKIYVCDHCNSKRRKFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVVFEETLNMEPYCCSETLNALRPECFIYNLSAVVIHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMEEVLRAQAYILFYTQRVTENGHSRLLPPELLSNSQQHPSEETDTSSNEVLS
The following text describes a protein:
Function:
Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Secreted, extracellular exosome.
Sequence:
MVLRRARILGAVLLCFQAAAVLSQLADTSLPPEDQDSSGDDDDAFSGSGAVPSEYPVVTWNVPLQESSNVSLVPPASTDSGDHQPEVQRTDNPTEDYTTAPVSTISMAVFPVIDHVPDKLKEAVEDGGLHPPSEHVMTTPTVTTTSIPVSHHISTVRISTTQTPTTGKIPEPEIYHDVRHIPFPDKNIPASDTVPPSERSLYTTSLPTTSSTVQKDISSPPEEIVRSDDGSGDVGDFVFPQLDENPVIEEEPALTNRGMDIPKDEKSEAAAQGILDRKEVLGGVIAGGLVGLLFAGFLVGFMLYRMKKKDEGSYSLDEPKQSNGGYQKPQKQEEFYA
The following text describes a protein:
Function:
ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
Subcellular Localization:
Nucleus.
Sequence:
MANVDVSPGKIAGFGIPLLDFIADVDDRLLDRYGLECDSSNQATEEQKVLYDELSRHPRVQVIPGGAVPNALRIAQWLLGIPNITMSFGCIGDDAFGKILTDKSQSEGVYVQYQVHPTQPTGTCAVLITGQHRCLVSNYAAAKHLSSDFIFEDETWRHIKSASCFYLVGYFIHTYPSISRELADFARRENKVLTMNLSAVYVCEQSSQLLTQMIEHAQYVFGNKAELQAYASALDWQDTEESVMMKMSRIPSKTENPTRHVIITHSSQPTLWCNGTAVRSLEVPRIAEDKIVDTCGAGDAFVGGFLSQLVQHKTIEECIRCGHYAAGLSIQQRGMTITGSPSFR
The following text describes a protein:
Function:
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK. May catalyze the hydrolysis of aspartate from the carboxy-terminus of target proteins. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of target proteins.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MSEDSEKEDYSDRTISDEDESDEDNFMKFVNEDIHQCALLTADSISDPFFPRTTQILLEYQLGRWVPRLRKPRDLYGVSSSGPLSPTRWPYHCEVIDEKIEHIDWTPSNPEPMYIPTGLEVEPLYANSKEETVVYLAEDAYKEPCFVYSRVGGNRTPLKQPVDNCDDTLMFEARFESGNLQKVVKVGEYEYQLTVRPDLFTNKHTQWYYFQVTNTQAGIVYRFTITNFTKPASLYNRGMRPLFYSEKEASAHNIGWQRIGDQIKYYRNNQGQDRHHHFSLTWTFQFPHSKDTCYFAHCYPYTYTNLQEYLSGINNDPVRSKFCKIRVLCHTIARNMVYILTITTPLKNSESRKRKAVILTARVHPGETNSSWIMKGFLDYILGNSSDAKLLRDTFVFKVVPMLNPDGVIVGNYRCSLAGRDLNRNYTSLLKESFPSVWYTRNMIRRLMEKREVILYCDLHGHSKKENIFMYGCDGSDRCKALYLQQRIFPLMLSKNCPDKFSFSSCKFNIQKSKEGTGRVVMWKMGIRNSFTMEATFCGSTLGNKRGTHFNTKDLESMGYHFCDSLLDYCDPDRTKYYQCLKELDEMEKHINLEKVIDDSDTSLKEITLDLETSSHASDSSESNDSQTDLLKLNSQIKTKKKQLKTKKERNSTIERHQNIREEEQEVCDKGHLVQRHKESDSDVTDTRPSISDDCIFDYFRRQLPNQGFFKILGLKFYCGYTHMISQTVIQKLSRDQQRCVLGTDKKNQETVQPRNNDLYGNCIKVTSLKCPLNKQTPIWTEKTRIPTEDLHHNLKSNMKECPSFQSKKADINWTDDEKRIYRDKNIAQTQEILQYLLPIMRSTKNVQTTQIKEVFNPRTSFQIQHQQKPSSNINIRKCSTSWTPPRNLPLISQRTLIVSTSKWLQPLDWKSSESSLPLGGPKKRRKYSRVKATKTKDMKAASSKWEMTPSSSEKDADKSLQAEGSSQQGTMQTAPHPTKTKGEQPKKKHGQPAFHLKLQRDT
The following text describes a protein:
Function:
Serine protease inhibitor. Inhibits trypsin (Ki = 41 nM) and weakly inhibits chymotrypsin (Ki = 410 nM). Does not inhibit bacterial subtilisin.
Sequence:
GRRPCCNECGICDRSLDPMCICEDLVPQCHEGCQACEEVDTGTPMYQCRSFEYYHCGTPCL
The following text describes a protein:
Function:
This promotes the activity of RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MAEKTMCISQQQTKPIKILKWKVSEGNTVSIGRVILLYDFDGASKVEQRKLKVTQAGTIFKIVAQEGAIVKPGETLCELKECTHPTVMNDMCAECGTDLRKNDVSVAASVPMVHAIPDLKVSEELAQKLGKADVDRLIRDRKLVLLVDLDQTLIHTTNDHIQPNIKDIYRFQLYGPNSPWYFTRLRPGTHQFLNNIYPFYELHICTFGARNYAHMIAAVLDRDQKFFSNRILSRDECFDPTSKKANLKALFPCGDNMVCIIDDREDVWSNAANLIHVKPYHFFQHTGDINAPPGLDKHENDNKGVDLTKIKDQKKDEQIQNNDSKATENDSDKNGENVEESKVENQVSNESESTKNESKENTEDNEGNNKDKVDENKNGDDSSEQKIENVESKGVNGEAVTNDEKPPPEESKTQTEGDTKTETPPETKNAIEINNHLVEVEDPDDYLSYLEDILKRIHQAFYDAYDKMESGEVPDLKKVIPGVRSQVLQGYKLVFSGLVPTHIKLEQSKAYQIAKSLGAEVTQELEDDTTHLVAVRPGTAKVNAGRRKKNLKIVTPDWLWCCAERWEHVDEKIFALNSKGSKNRHPPPHCSSPEHIISYPEHNTPAMRKRTPSGRFMDTINPLMSFSSADIADMDKEVEDILDDESDSSDEEKNAKATVVNSEEVHENSSSSDDSLGDHPKGFKRKREGGDEAEIDLNNSTEDDETPSVKFRRGETVDSEVDMEPDSQDSDGSVEAPDEVDDGEWNMMGAALEREFLSNN
The following text describes a protein:
Function:
Endothelins are endothelium-derived vasoconstrictor peptides.
Subcellular Localization:
Secreted.
Sequence:
MELRALILLGIIVTSNTGFAVVSLPQPPGGKLLNQLLKEGARKGSRGEKESETNPLQPTGSVPLGTASPGPQGTPIPGYEQRSRTSHLPGDSGGAHRRDRRCTCYTYKDKECVYYCHLDIIWINTPERVVPYGLSNYRGKRSAVRRSRSSEPRSRCSCEDIGDRQCVYFCSTTENRRRDQTSAVWTQKDSILDQKRLLAEA
The following text describes a protein:
Function:
Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').
Subcellular Localization:
Nucleus.
Domain:
Contains two direct repeats of 7 amino acids in the N-terminus.
Sequence:
MPGISSPILTNAQGQVIGALPWVVNSASVATPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPQPVAVRKPSTPESPAKSEVQPIQPTQAVPPPAVILTSPAPALKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQIP
The following text describes a protein:
Function:
Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MASGGEGAGSGESPPAASVEAAAVEATLHIRCANGSKFTVQTDLGATVGAFKEVLSGSCGVPAPQQRLIYKGRILKDEQTLDSYGVETDHTIHLVRGVATPAASSAPAAANPLASFTPSSGPAGGLGGLFPGVDAPGNDRPSGIFRPGFPELEQVEQHLSQNPNLMREIMNMPAMQNLMNNPDLIRNMIMNNPQMREIMDRNPDLAHVLNDPSVLRQTLEAARNPEIMREMMRNTDRAMSNIESSPEGFNMLRRMYETVQEPFLNATTMGGEGSTASNPFSALLGNQGSSQPGQGQPATNAPTTGSESTTGTPAPNTNPLPNPWSTNAGSAQGATRTPSGNARTGGVGGTGATGGLGGLGSPELSSLLGGLAGSPRTGSAGGLGGSGSPDLGSMLGGSPDVSPFSQMLQNPAMIQMMQNIMSDPQTMNQLLNLNPNARNLMESNTHMREMFQNPEFLRQLTSPETLQQLLSFQQTLLGQLGQHQPSQGGNNAGSATGTRGNPSLDTLMSMLSGLGSGGGLGVPNTSSGEYIYTIVGELGCSYIISGLQLLLHDLISVPPEELYATQLTQLQEMGFIDTAENIQALVATAGNVHAAVERLLGNLGQ
The following text describes a protein:
Function:
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of IAA6 by regulating the activity of the Ubl ligase SCF-TIR complex.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDLSPVKEALAAKSFDKIADICDTLMLQVASEGIEYHDDWPYAIHLLGYFYVDDCDSARFLWKRIPTAIKERKPEVVAAWGIGQKLWTHDYAGVYEAIRGYDWSQEAKDMVAAFSDLYTKRMFQLLLSAYSTITIHDLALFLGMTEDDATTYVVENGWTVDAASQMASVKKQAVKREQKVDSSKLQRLTEYVFHLEH
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Domain:
The RING-type zinc finger domain is responsible for E3 ligase activity.
Sequence:
RQSHLAAEPSGSGAHGFPECSICLDAARDPVLTCCGHLFCWPCFYRVPKVDSWSSTKECPVCKGEVSDDTVTPIYGNDGGPAVTEYSSGLIRIPPRPKARRVESARQRMAGGPLEGVLSDAVRDVESGGENINLGVI
The following text describes a protein:
Function:
Alpha-1,2-specific exomannosidase involved in endoplasmic reticulum-associated degradation (ERAD). Delivers misfolded glycoproteins to proteasomes. Forms a complex with PDI1 to process unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2, promoting degradation in unfolded protein response.
Miscellaneous:
MISCELLANEOUS: Present with 656 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MVCCLWVLLALLLHLDHVACEDDAYSFTSKELKAYKQEVKELFYFGFDNYLEHGYPYDEVKPISCVPKKRNFEDPTDQGTNDILGNFTITLIDSLTTIAILEDRPQFLKAVRLVERTFPDGNFDIDSTIQVFEITIRVIGSLLSSHLYATDPTKAVYLGDDYDGSLLRLAQNMADRLLPAYLTSTGLPMPRRNIKRKWDVSEFPEFLETENNVAAMASPMFEFTILSYLTGDPKYEKVTRYAFDKTWSLRTGLDLLPMSFHPEKLTPYTPMTGIGASIDSLFEYALKGAILFDDSELMEVWNVAYEALKTNCKNDWFFANVMADTGHLFVPWIDSLSAFFSGLQVLAGDLDDAIANHLMFLKMWNTFGGIPERWNFSPPEFPPLSPLERSGAVALDNILPLEWYPLRPEFFESTYFLYRATKDPFYLNIGVHLLKDLKQRFKSNCGFAGFQNVITGELQDRMETFVLSETLKYLYLLFDEENELHNSASDVIFSTEAHPMWLPQEVRSNYKRNAKFNNSVYSSHLEICQKKDREQAGENTLSQRIVGFAKSIFHKGPPDEEATDPIIDYTIDTELPGTCSIKPHHVIGDEFWYSPMLSNFDRLFEIDSRFAATLIKPSHMHNYNAIELEPGFYNRWSNPQFSTCLIPPTTEIFELLFDLPGYHQLNPLMLENKTITFETFGGRSRLKIEKLQIYQIDYYGDLITASTFQDVSRKDIFSNACDAVASLYSPTYLYRVVAINGRILPRHGSVQIKKHSPVLTSNGTREEDEFKMDGIGINDHSQLMLECTPIINLFIV
The following text describes a protein:
Function:
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Sequence:
MTLSANRTSRIVVASAVAILFSASACTISMQTVSAFVPAIPARLSSISTLKGREGSVFYKTTSAPETTTTRRQSTKNPTSNRQPQQSKLQTVSNGKNPKVFYPKKKSSSKKESSTKRTSKLQSQSKSFKPLKDLKLGSKVSGTVVDVCDFGAFINIGYASRGLLHISQIQDTRVANINNVFKVGDTVEGARVINVDLAKGEVGLSLRSKRPKRVDLNKFKVGDTLEGKVDSVVSYGVFVDVGASTNALLHISRITGSAIENIRHHLNEGDPVSVHVIDIDVERKTMAVSMLDKKADQYLDRRMSQRMKRFYGTAKKSVPVEDVDDESELDYFDQAIQELELALRERES
The following text describes a protein:
Function:
Probable transcription factor. Promotes normal hermaphrodite (XX) development, in concert with histone deacetylase hda-1 and nasp-1, perhaps as components of a complex. May cooperate with transcription factor tra-1 to repress male-specific genes in hermaphrodites. Synthetic multivulva (synMuv) class B protein, required to repress the induction of vulval development by let-60 Ras signaling.
Subcellular Localization:
Nucleus.
Sequence:
MDDPNQCTIKQEDSITRPRPTEAPTIQNLKQEPAIEEGSSSTMDNMLMLTIDTNQANWQGTYDDDEMDLNNKTDLIPLLETEKTTINEDELYDDEEDDDDDEEIKKGIGFELLAQALGMSAKVPVEKEEPEKERAKLSGVGEFMKQIRGEIKPIQKERIVLDELGFRVRDPSKFPPCRIAEVQQTLTLADHQDGIDLPPPNAPTDVRIVRKLIRQKMVRCKKCKNRFIEKNIYERHLRDKHPDLYEEYIREQEEEVELQRLEEIEANRIEELQTGGFIPPENEISQPSEDPNYIPLPGENNGGLVPRFDYYGRIKQLKRPYKKKVSPQCPFCDKRFRNEFSLKKHFAKKHEEMVEFQQCLKCFKCVENDAEMANHDCELTYVCFECTPIRNLCTDNRLLNHRKKFHRGANSGFRCSFCNMKFLTPRKLRKHKKMSHVFTKTFQCHFCEEIFISEVAVMTHERMHTGIIKFECKVCDFRANRYTAMEEHKRDEHGYVCAICHERHAEYPEMKHHVYEEHGGYLAADEPTAYVETPRMWILYKGE
The following text describes a protein:
Function:
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTTAPYSRTKPLASRSDLEKNLEKGFKYLTLAFAVSIGLILLAIALLILSQSVPAIKAFGLGFITNNTWNPVTSQYGILAIMVGTLVNSGLALLLAIPLGIGTALFLSEDFIPSKIRTVLTFMVELLAAIPSVVYGLWGIFVIIPLIKPVGMWLNEYFGWIPLFSTPPAGPGMLPASIVLAIMILPIITAIARDSLASLPPELRQASLGLGATRWETIFRVLIPAAFSGIVGGIMLALGRAMGETMAVTMIIGNSNRLSWSLLNPANTIASLLANQFAEASGMQVSALMYAGFVLIVLTFIVNILAELIVNKVKAKY
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC).
Subcellular Localization:
Nucleus, nuclear pore complex.
Sequence:
MPSRSTVTATAVVSYDWGTSSDLKALYIQTYTIFTSLQRIHQEALLTDRAGRSATANSVLPSAETIQYYNRISEHYARAIQDYLDRIQLDDSVDAAQFQAWRDVQTILRLAEVLYYPKDGRGVSVVGEELLHWLNSFDVAPTTEEGQEIAESAVPHDHPSYWDYVLRCVLRGFHTSAASVLKSLDSHPSAVIRSVAQKAAKLLFTLPRSTHFSMEHEFVAAHRSWLANVRKLISGLEHQMDEMEVEAGNTEEVEDERLEYEAQFRCLLELMAGVKDRIFEACEDWREALGAWGTLVHPTLKRDDVPSTAAIILEQFPIDGTIPSELVQQYLIKGEVRQAVQKAQDVDIWLGAHLADLAEKVGLIEDDEQTESGDLRQDLLFKYAQSLLDEQGLWRICIDYLAACGEAGRRKSSHIILSVPLDGPDTDEESEEANNAMEEDADGVNGAPSNKTKRVARAEQVLRACSDHGLELEARVVCRRMSQKLMEQGEYGMAIAYCVRASDTVLIRTIGDRILGEYVTRGAEAFNQIVDSFPSSLITPADGLEFNGDNLDGEQDAVLEKHARGFFSKRLAFLARFRDFHRLYADGQWAAAAGLLVELVTTEAAPERFLAVLLVDAIPLLEDGQATWFDRSQTFELIRIVERITNAVSMHPDMYEHFLGFLHQLLGIKSPKQQQQQPKTQTGPNKQEVLSSVKASDKLDAVRLSLARNLARVGVMQAGIV
The following text describes a protein:
Function:
The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endomembrane system; Peripheral membrane protein.
Sequence:
MMDIGRLHCFVVATKGGDVLYERFWDRFTELEKAEIRAAFSTASGNVRLQYDDQDFIAPYKTARFAFIPSADTVFYLMGSGEYDELGLVEILRVIISVLKDVLGKAPSAALLLDKYARLCLVVDEVINEGLLEAVDKEAIKKGIKGKAPWE