lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Negatively regulates the expression of the efflux pump Rv0191 upon chloramphenicol exposure. Acts by binding to the Rv0191 promoter region.
Subcellular Localization:
Cytoplasm.
Sequence:
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAKAVAR
The following text describes a protein:
Function:
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
Sequence:
MTSIVEALVPGGKANPGPPLGPALGPLGVNIKEVVEKINEKTRDYNGMQVPVKVIVDDKKNVEIEVGTPPTASLVMKELGIQKGSGNAGSEVVGNLTISQVAKVARMKKEDVLSYDLKAAMKEVMGSCVPMGVNVEGMKAKDCQKALDEGKFDDLLAGEAW
The following text describes a protein:
Function:
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAAIWGNGGQAGQFPLEQWFYEMPPVTRWWTAATVATSVLVQCHVLTPFQLFYSFRAVYVKSQYWRLFTTFLYFGPLNLDLLFHVFFLQRYSRLLEESSGRSPAHFSWLLFYAMASLLVLSPFLSLPFLGTALSSSLVYIWSRRNPETRLSFLGMLVFTAPYLPWVLMAFSLVVHGIVPKDEICGVVVGHVWYFFNDVYPSLHGGHRPFDPPMWWVRLFESGPGERGTDAANVNGEFAAAAAPEVR
The following text describes a protein:
Function:
Appears to be proteolytically inactive.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MKWLVLLGLVAFSECIVKIPLRRLKTMRNVVSGKNMLNNFLKEHAYSLSQISFRGSNLTTHPLRNIKDLVYMGNITIGTPPQEFQVVFDTASSDLWVPSDFCTSPACSTHVRFRHLQSSTFRLTNKTFRITYGSGRMKGVVVHDTVRIGNLVSTDQPFGLSIEEYGFEGRIYDGVLGLNYPNISFSGAIPIFDKLKNQRAISEPVFAFYLSKDEREGSVVMFGGVDHRYYEGELNWVPLIQAGDWSVHMDRISIERKIIACSDGCKALVDTGTSDIVGPRRLVNNIHRLIGAIPRGSEHYVPCSEVNTLPSIVFTINGINYPVPGRAYILKDDRGRCYTTFQENRVSSSTETWYLGDVFLRLYFSVFDRGNDRIGLARAV
The following text describes a protein:
Function:
May play a role in the spermatocyte cytoskeleton, possibly interacting with actin.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MRFCNSKLTSIDNRCDVAIISKDEERFEVKLVESEIARELNRLGALSPRSMQKNILVPFTTQTVKYLLGLEKVSDSTDEMGWFGIEKSLEEIAGFGQHCFPKILEMKNTICDHILSTLSDVNCFLLHKKFREFDCQNHAHKTLEYILYNLARMVVVDKRVDVEFYRLPVEEVKHLLSSEEVNVEQETQIIEVINQWIAADFENRDKFRPMLMSTVRFLALDQQIAKSLSQFHPSLKPARRTRDVLIIIGGWLHRQACDRIEWFDPENNCWKVSQQKLPTTLAYHGSAIVDGILYLFGGSTGQRTRCETWKLSTETWQWDRCNNMMEPRNYISNSSVVYDGRIYVFGGQNFREITRTAVRSRTGEVFDPKTNKWTETASLSDMRSDCAAEVFENQIYVSGGFNGDMILASVEVYNPIGNVFSRTVDLPYPITGHCLLNHGNQLLIVGGFDGAERQNKIWMWHRTGEWQQRPEKLIYGRSTSAACSYKGWLFSVAGYTEKVEATCEILLPEPNASRFSFIPDVPRAKSALNVLVAPNWRNFLERRGTINEQSMEMDDDYEDDAGASYMSINN
The following text describes a protein:
Function:
Enzyme involved in the catabolism of H(2)CO(3) but that does not mediates the reversible hydration of carbon dioxide. Mediates complex I assembly in mitochondria and respiration. Binds HCO(3)-. Required for male fertility during anther development and dehiscence to regulate the secondary thickenings of the endothecial cell wall, probably by modulating H(2)O(2)-dependent lignin polymerization.
Subcellular Localization:
Mitochondrion membrane; Peripheral membrane protein; Matrix side. Note=Probably integral to the membrane.
Sequence:
MGTLGRAIYTVGNWIRGTGQALDRVGSLLQGSHRIEEHLSRHRTLMNVFDKSPLVDKDVFVAPSASVIGDVQIGKGSSIWYGCVLRGDVNNISVGSGTNIQDNTLVHVAKTNISGKVLPTLIGDNVTVGHSAVIHGCTVEDDAFVGMGATLLDGVVVEKHAMVAAGSLVKQNTRIPSGEVWGGNPAKFMRKLTDEEIVYISQSAKNYINLAQIHASENSKSFEQIEVERALRKKYARKDEDYDSMLGITRETPPELILPDNVLPGGKPVAKVPSTQYF
The following text describes a protein:
Function:
Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids (By similarity). May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation. May be required for proper maturation and function of a subset of inhibitory synapses (By similarity).
Miscellaneous:
MISCELLANEOUS: [Isoform 3]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Cytoplasm. Postsynaptic density. Cell projection, dendrite. Basal cell membrane. Postsynapse. Nucleus. Note=Localized at inhibitory synapses on the dendrites of cerebellar Purkinje cells.
Domain:
The coiled coil domain may mediate the interaction with dystrophin.
Sequence:
MIEESGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTREPPHPVFPEQPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIASYVARLQHCARVLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHCPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSAEEGAEEEEEKMQNGKDRG
The following text describes a protein:
Function:
Stimulates the DNA unwinding activity of PriA helicase, which does not seem to require single-stranded (ss)DNA-binding by PriB. Activates DNA-dependent ATP hydrolysis catalyzed by PriA. Weakly binds ssDNA. Weakly binds double-stranded (ds)DNA, a partial duplex DNA with a 3' ssDNA overhang, and a forked DNA structure with fully duplex leading and lagging strand arms in vitro; Involved in the restart of stalled replication forks, which reloads the replicative helicase on sites other than the origin of replication; the PriA-PriB pathway is the major replication restart pathway. During primosome assembly it facilitates complex formation between PriA and DnaT on DNA; stabilizes PriA on DNA. Stimulates the DNA unwinding activity of PriA helicase.
Sequence:
MGFTNLVSLAALIEKAFPIRYTPAGIPVLDIILKHESWQEENGQQCLVQLEIPARILGRQAEEWQYRQGDCATVEGFLAQKSRRSLMPMLRIQNIKEYKG
The following text describes a protein:
Function:
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity). Plays a role in the physiological regulation of the intracellular CoA concentration.
Miscellaneous:
MISCELLANEOUS: Present with 3610 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MVEENSRVLIVLPYTPPSATLQRIIGQTIPFLRECQSQLDIVIVPEFKTSFQLDSALGKMYSITRDVLLGYGMINSGINIIFNNIHFVESNLQWKVVLLPQESTFETWKLELGQGQYHSIEHYALHDNIMEEIEGPKDANKFHVTALGGTFDHIHDGHKILLSVSTFITSQRLICGITCDELLQNKKYKELIEPYDTRCRHVHQFIKLLKPDLSVELVPLRDVCGPTGKVPEIECLVVSRETVSGAETVNKTRIEKGMSPLAVHVVNVLGGREEDGWSEKLSSTEIRRLLKSSASPTCTPQNPCV
The following text describes a protein:
Function:
Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils priming T-cells toward effector T-helper 2 subset. Associates with pattern recognition receptors CLEC4D and CLEC4E to form a functional signaling complex in myeloid cells. Binding of mycobacterial trehalose 6,6'-dimycolate (TDM) to this receptor complex leads to phosphorylation of ITAM, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes. May function cooperatively with other activating receptors. Functionally linked to integrin beta-2/ITGB2-mediated neutrophil activation. Also involved in integrin alpha-2/ITGA2-mediated platelet activation.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MIPAVVLLLLLLVEQAAALGEPQLCYILDAILFLYGIVLTLLYCRLKIQVRKAAIASYEKSDGVYTGLSTRNQETYETLKHEKPPQ
The following text describes a protein:
Function:
Involved in chromatin organization.
Subcellular Localization:
Nucleus.
Sequence:
MDANKAAETAAKENAADKVSDVENASVTAGVAKAVGAQPERGSKDAAESPAAVDASASAATDDVADKKAKGDSTAVSNTESDAAAADKKEKSPSPVIKKSNNKDAKKEDNSEKDEENSEDGDEPEDEADEKASDEESEKKKPKLDAEDKIKDATDESKPKSGADKPKKPEPKAKNGKVAKEEDDDEEDEDDEDAEDDDGDENDGLDKNNEVAEDDENVVALAEIDRINENINKTRVDGLQTLHAICFGAQGKNNVVKKNLRSFAGFEFAKDSAEYNKKLEAIKKVDNKGLRSICEILTLDRKGSKNETVLRVLKFLMEPDESLCLEQGDEEEEEDAEDEDLDEDEEDPPSEEDKKRKSGKSSGGAGRGSARNSTGRPRRATAGKKMSAYVDFSSSDDSEQKVAVPKRRRNDDSESGSDYNPSANSDSDGGRGGGAGAAGRKVPSRGGRGRPARKSRRRNSDSEEEEESEVSDADSDVPKRKRGSVGKRGRPAAPASAGRRGRGRGAASRKRKDSDSEDEEVSEDEEEEDVSDFASDQSEEERPKKSKKPITPAKNSKANNKSKPAGKADSRSKKSKKESSEEDDDVDDKDESDEDEPLTKKGKQAFPTDEQIRGYVKEILDKANLEEITMKTVCKQVYAKYPDFDLTDKKDFIKATVKALIAT
The following text describes a protein:
Function:
Negative regulator of the mitotic exit network (MEN), required for multiple cell cycle checkpoints. Required for daughter cell separation and chromosome stability. Involved in copper sensitivity.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSAEKSKIEHAPWAWGLPVTPPRAAAACAASPWTPRVPADIAQAGGRAGTPRRRAPARTLGHVIFAVPELVEQLVRFVAAGSEQAGAPRALHHCLLVNRLWHAVTVAVLRERLYFADARRLRQFAAAAHRGRLAPELVVLHKLTRLEQRDLDRALQHVSPERLRRLELYVCPRVLPPAGYLGRAGGLRRLALPGNKLVSDDFLIEACVHLPRLQVLDLRACDRVSDAGVVAVATNCPRLHTVNLGRHRNGHLITSVAVVALARHVQLETLGVAGCDVSDAGLWELAAVCGPSLARLSLNNCRYLTNRSVPALLELNAFPNLSVLELRNIPHLTDVRAVVRYRQWKRACGLPVLVEGCDRLTQLFRCEERKLCKENCASPVRDLAAWLRSEED
The following text describes a protein:
Function:
May play a role in stationary phase survival.
Sequence:
MKQHQIRKAVIPVAGLGTRMLPATKAIPKEMLPVVDKPLIQYVVSEAIAAGIKEIVLVTHASKNSIENHFDTSFELEAQLERRVKRQLLEAVQSICPKDVTVISVRQSQAKGLGHAILCAKSVVGDAPFAVLLPDVIIDEASCDLKTDNLASMVSLFDETQVGQIMVEGVPHHLVNQYGIADVNGHDLQPGESEPLVELVEKPPVDEAPSNLAVVGRYVLPAAIWPLLAKTPAGAGDEIQLTDAIAMLMKEETVNAYYMQGKSHDCGNKQGYMRANVEYALRHSEIGEDFAHYLKTVVKGIK
The following text describes a protein:
Function:
Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface (By similarity). Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound.
Subcellular Localization:
Secreted.
Sequence:
MRSLQMLLLAALLLGTFLQHARAARATNVGRECCLDYFKGAIPIRKLVSWYKTSVECSRDAIVFLTVQGKLICADPKDKHVKKAIRLVKNPRP
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSRQQNEEDTNSVLFDARNEYYIGNFMGSINFVLPEQGTAGPELLSYMYLSYLAIDSGRIVASDIKEGNSTPLQALRLVHEAFEQPSRTEELLEKLTDKVAGEEDETNIWHLATAIVYCHDGQFENALKILHGSTNLESMALSVQCLLRLQRVDLAKQLVAKMQEISDDATLTQLAQAWVALAQGTEQMQDAFHIYQEFCEKFKPTPALLNGQAVVHLGLERYEEADSVLRESLLKKHNDYDTLINLMVHAHLTGKPTEAITRNLEQLRQFYPKSDFVTDLDKKSAEFDRLCLQYDVEGGEKLLAV
The following text describes a protein:
Function:
May be involved in mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MQGFNMGKYIPPEGPNAKRKFDKLRNVIRFEMPFPVWCNNCENIIQQGTRFNAVKKEIGSYYTTKIWSFSLKCHLCSNPIDVHTDPKNTEYIVASGGRRKIEPQDINERPAKAENDEKVPSDAIEALETQLTQQKSEKHNSSVINFIYEKNERLWSDPFVSSQRLRKQFRERKKIEKKQEAKDLSLKNRAALDIDILPPSSSDKDKALLLLDNELGKNKFIRKLDYRRTLMPSSRTFSTFAKFAETSFAKKDPFARKFVPSEKLRSEQRKFPTENLKGEKILEDNSVSLVNYEVSDDEG
The following text describes a protein:
Function:
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSEEKPTVRTEEDDRYEDDAGDLDLGQIGSRVWLVKIPKFLMDKWNSIPEDDAANLGCVRVKNDEIQLLLQNSPENADVPKIYNLRVMNKFVRNSYVFRESETSSSMKSTALVGTVAHECNVSPVINDDYRRVMQKRALAASAPKRKVQMIDDRGGSLLAPGTLGSRSRSTTSFIRNVKPRTGEGLKNSRIPRNELLDILFKCFEDYEYWTLKGLREYVKQPEVYLKEVLDSIAILNKRGPYALKYSLKPEYKGTMDAASVELRNQQASQSESSSIDHTGKNTSPDNPGTNAEEDEDDDGVEMIDVV
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent O-methyltransferase that catalyzes the last step in the erythromycin biosynthesis pathway. Methylates the position 3 of the mycarosyl moiety of erythromycin C, forming the most active form of the antibiotic, erythromycin A. Can also methylate the precursor erythromycin D, forming erythromycin B.
Sequence:
MSVKQKSALQDLVDFAKWHVWTRVRPSSRARLAYELFADDHEATTEGAYINLGYWKPGCAGLEEANQELANQLAEAAGISEGDEVLDVGFGLGAQDFFWLETRKPARIVGVDLTPSHVRIASERAERENVQDRLQFKEGSATDLPFGAETFDRVTSLESALHYEPRTDFFKGAFEVLKPGGVLAIGDIIPLDLREPGSDGPPKLAPQRSGSLSGGIPVENWVPRETYAKQLREAGFVDVEVKSVRDNVMEPWLDYWLRKLQDESFKKSVSRLFYSQVKRSLTSDSGMKGELPALDFVIASARKPGA
The following text describes a protein:
Function:
Functions in vesicle-trafficking events required for site-specific cell wall modifications during pollen germination and for anchoring of the cell plate to the mother wall at the correct cortical position.
Subcellular Localization:
Cytoplasm, cytoskeleton, phragmoplast. Note=Localized in the forming cell plate and the cortical division zone (CDZ) during cytokinesis.
Sequence:
MDILFAQIQADLRSNDALRQSSALLQALQQSAAGRDISVIAKSAVEEIVASPASAVCKKLAFDLIRSTRLTPDLWDTVCSGVKTDLHFPDPDVTAAAVSILAALPAFSLPKLISDCSSEIASCFDSPSDNLRFSITETLGCILARDDLVTLCENNVGLLDKVSNWWARIGQNMLDKSDAVSKVAFESVGRLFQEFDSKRMSRLAGDKLVDSENSLAIRSKWVSSMVDIVWRKRSALMARSLVLPVETFRATVFPLVFAVKAVASGSVEVIRQLSKASSAAAAANATVVDSNAEKLVGVSDLVTHLAPFLASSLDPALIFEVGINMLYLADVAGGKPEWASQSIIAILTLWDRQEFSSARESIVRAVVTNLHLLDLHMQVSLFRRLLLMVRNLRAESDRMHALACICRTALCVHLFARESARRGQKPLPGTDIISLFEDARIKDDLNSVTSKSLFREELVAMLVESCFQLSLPLPEQKNSGMESRVIGALAYGTGYGALNWTEPALEVVEVCRPCVKWDCDGRTYAVDCYLKLLVRLCHIYDTRGGVKRLKDGASQDQILNETRLQNLQRELVKDLQEVNTPRILGRLIWTIAEHIDLEGLDPLLADDPDDPLNIIIANIHKVLFNLDAAATTSNRLQDVQAVLLCAQRMGSRHARAGQLLTKELEEYRNHAAADTVSKHQTRLILQRIKYVSNLPERKWAGVSETRGDYPFSHHKLTVQFYEPSAAQDRKLEGLIHKAILELWRPKPTELTLFLTKGVDSTSIKVPPTAYPLTGSSDPCYIEAYHLADTNDGRVTLHLKIINLTELELNRVDIRVGLSGALYFMDGSPQAVRQLRNLVSQDPVQCSVTVGVSQFERCGFWVQVLYYPFRGARGEYDGDYIEEDPQIMKQKRGSKAELGEPVILRCQPYKIPLTELLLPHKISPVEFFRLWPSLPAVAEYTGTYMYEGSGFMATAAQQYGASPFLSGLKSLSSKPFHRVCSHIIRTVAGFQLCYAAKTWHGGFVGMMIFGASEVSRNMDLGDETTTMMCKFVVRASEASITKQIESDIQGWCDDLTDGGVEYMPEDEVKATAAEKLKISMERIALLKAAQPKKTSKIEEESENEEEEEGEEEDDDEEVKEKKEKEEGKDKEEKKKKEKEKGTFSKLTAEETEHMALQAAVLQEWHILCKDRKYTKVN
The following text describes a protein:
Function:
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Binds nickel and transfers it to the membrane-bound permease. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI). May bind nickel via a nickel-chelator.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MKFKRLATIFSAVLVLSGCGSMHSSGKDLNISLPLKTKSIAPYETDVPVKIGAAESLFKTNDQGKIEKALVKSYHQPNDTTLDIELKDNIKFQNGQKLTAEKVKSSLENSMKKSDLVKYSLPISSITAKGQKLTIKTNSAYPELVSELANPFMAIYDTDAKSDVNQTPVGTGPYQIKDYKQSRKISLSNFKDYWQGKPKLDHITVTYQEDGNNRVRNLESQKDDLITDVPVNKVQDIENNQNLKVSKESGFRTSLLMYNHTNKKMTKSVREALDHIIDRQGIADHIYQGYAKPATSPFNDKIPYIKEPKLTKQNIEQAKMLLAKDGYTKEHPLKIKLITYDGRPELSKIAQVLQSDAKKANIEIDIKSVDDIEGYLKDRSAWDATMYSFGTIPRGDTGYFFNQAYKKDGAINKGDYNNSNVDDLINQLNHTVDVKERHNISNDIIKLSSRDVPNSYIAYNDQIVAANSKVKNYKVTPEGIYLIDYRTTIER
The following text describes a protein:
Function:
Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of 3-phenylpropanoate. Functions as a chaperone protein for folding of MhpE.
Sequence:
MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEANVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIASKSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA
The following text describes a protein:
Function:
Probable 2-oxoglutarate-dependent dioxygenase that may be involved in glucosinolates biosynthesis. May play a role in the production of aliphatic glucosinolates.
Sequence:
MIKMGGNETRELPIINLSDKNLKQNTELWSFTRDSVREAMEHHGWFVAEYNNFPTGLHQSILEAAKELLDLPVEIKLKNENHKAGHGYITMMSDGQPVHEGLGIDQVNDVQQCRGFSRLMWPDDHDDNDRFCETVHAYAKMQAELEQLVIRMLFESYNVEKYTEKYIGGTRYLLRLLKYRRLPNGEPNRKFISHTDKSFISILHQNHITGLMLKSEKEDVWYHFTPSPTRFVVIAGDAIMAWSNDRIKACYHKVEMESVEMRYSLGFFSFQEGMISTPEEMVDKDHPLAYNPFHHDGLLEYYETLEVHLKAHRTMTKAYCGIP
The following text describes a protein:
Function:
Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3' (By similarity). May regulate the transcription of specific genes during normal development. Mediates SHH signaling. Plays a role in cell proliferation and differentiation via its role in SHH signaling (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MASRQCPPAAVFNSMNPPVNSYVEHCYLRSPNVMAEGMNEMPYCHQTNLMTSHHGFGLAQGSDHLAGTDGSRFSTPRSTMKLSKKRAMSISPLSDASIDLQTMIRTSPNSLVAFINSRCSSASGSYGHLSIGTISPSLGYQNCLNHQRPQAGPYGSNPLMPYNSHEHLSSRGMSMLQPRSSVKHCQLKSEPLSITGLDTIGSKRLEDGSEGDISSPASVGTQDPLLGLLDGRDDLEKDDGKHEPETVYETNCHWESCTKEFDTQEHLVHHINNEHIHGEKKEFVCHWQDCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHITKKHRGDGMLRAQPGHEGPGNQNVKGENQLDMEASSACKEDGRLAVPDITLKSQPSPGGQSSCSSERSPLGSTNNNDSGVEMNANTGGSFEDLTNLDDIPSVDSMGTAGASALRKLENLRIDKLNQLRKTPSSGKMVKLPSIHNSGPQGDMSVVCGPLGMSHNQHGIELPASSHVNHLNDRRNSTTSTMSSAYTVSRRSSVVSPYLPNQRAGDSGNMVDSYDISTDPSGHSNEAVCASGLPGLTPAQQYRLKAKYAAATGGPPPTPLPNMERMNTNNRMAFASSDYRGSAISSLQRRHSSNEYHNYGTGIIHPAQAPGAGIRRASDPARTGGDIQAVPKVQRFKSMTNMNVSMMGRQGTSIQQAYGGSDANLQRHMFSPRPPSITENVFMETAGPDEVCHTKEQGFIQSNEMQHYMNYQGQGSQLTAPNDHMNFNPQIHGLDGQSQNVYSHSQRAISNMHLNAENYSGQSNVSNFNQCQMTAHNQHFQNTRQAYNCANLPVQWNEVSSGTMDNPVQRPNHQIMHQNMSPGNHCQSQLSNCTVPESTKQGCPVNRNSCQQGMYMNNQKYNHGGQVQVKPEQQFHHSAPAMMSCQNMKHPSRQEHHFTKTNTMPLSSEATNCDYQGQQDSTQNSCFNVGLNLNLLSPPGRRSQTPIMQVKEIMVRNYVQSQQALMWEQHPKSMAMMTNSGDDVDTRQNQHKNTLNAAVYMGPKYMNYQGKPSPNNLMSPSSQDSQSSHTKAMGSPSSQCYNFDMMPHPPCGPKPLSRQHSVSSQSTYMGSPNQLSPSYQSSESSPRRMACLPPIQPQSEVTNNTSMMYYTGQMEMHQSKPGVHKLTTPLNLNQTSCDGHQHGQYNASHSFLKTVPYTSSCPAANTLDSLDLENTQIDFTAIIDDADNALMPGNISPNVLAGSSQASSHLTTLRNTGAVVPNMVVGDLNSMLSSLAGENKYLNTM
The following text describes a protein:
Function:
Catalyzes the hydrolysis of glucose from the disaccharide unit linked to hydroxylysine residues of collagen and collagen-like proteins.
Sequence:
REFRKTDPYVLESSILPNDSRFYPTVANGVVGTVIFSDTIYMAGLYNGYKGESHRARLQNNIPYVYVPDSTLWSTQLFTQDTKNGMFTICLSDTNVIVTQEIYAHKLLTNLLVTEVSVTYMSLNSTETLFYNSSYCNCSKDIPSSDCTKCQYLGSAIHKEFTTVTPEMNGSSHLTVHVIYSQFPKKLTVQNIGNNFTTKKFVFMFAVGETRASTIGNYIVGMGTVTANRLFQLHLNEWLRQWNSALIDVKNDIQSTQYMVSALYYILSNFPSTKNPQAKFYGVSPGGLPNGGSGVDYMGHVFWDQDFWMAPALLPFYPELVRKILTYRVRHLVGALAKAKSFGYEGADYPWETAYTGSDVCPGENYVEYEIHVTADIIHLLKQYIYATNDWSFLVECQAYDMLRQTAEFWSSRVTWNAIKGRYVLNNVMGPDEWHAPVNNSAFTNVAVAQNLNFAAEVATKLDCDEEKARRWQLIAKLLYIPYNETAHYHPEYDGFYSNETVKQADTAMLGFPLGLPMLESVQYNDLKVYNDCTSAFGPAMTWGMFAINWLQLNDTENAKLMYRRQLRNIHIPFNIWSENADSSGAVNFLTGMGGYLQSVLYGYFGLRYRNGSVTLNPTLI
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MDITKFVSEFRESAFLLGDYSTYHTQLSRRLRIVEKKLGRATPKNAKYAAKAPVTAEDIAKNNEFLHLLLLTSERAWAQAMAMKAAHSEDNADKNITGSTRKHIVSRLHKAVQTAKQIIQLLSDSGASGANDTDVLEAKAYRYALAGAEEFEKQAEGVKASSASPQRWNLCLTNYSAARVIYSSLLKATKKDLFKEVLGGTIDPSIRYAAYQSRIPRTVGVPAIARKFFPQDEADLVKAVKQLDAASLEEEDDASSPNIVDAAIGQALVSADAASAVLNDSQAGAATAKDRANAYDDILIASQDTVDATRRAIEELEKEGVDEGDARMQDLRVTNLAVNYDLISWRVGRNRVLIGADDGITFPPNPPQKPRRPRKDGKEWTEREEPTGRKLARLRERIALYDAILQSIDSVKELRGAARDTAFVSELDGPTCLLPGTEMPKLIAFIRIPVETKGGIGTLQSCIVPVVTGCICPAAFDVLSVRGVEIRGDRARLENLTSHYRGVVALSQLFANSDTASKVGLSNAAPVVERLNEYPISGSVDLKNLVTWPPKLKPVPVKPLFLDVAWNYVEYPGRTPAKQEPVPEKAPAEETQPERPAAKKGWFSFGR
The following text describes a protein:
Function:
Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity).
Subcellular Localization:
Cytoplasm.
Domain:
Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
Sequence:
MHLSKIIFLLIILFPYHVNSRKPIKYKNVNNVFIEIYPCKAIKWERKKKKRDLIKNNKLIHNVDVNYINMITNDNHISSEKCRDIKKKRKITSSEYGMSLEFFKKNPKKVVQNLKKRGMEKYLNVIVMLKKLINEKNENEVLRNKLRNRRKLLSDHIKNLIFNSKKYEDIINRDITNDSDHKTNLIHVDEEKKKTEKKNDTQDILKDNQKIRYINKENQATNNNINNQDNSNDVLKKNKIQIEEIKKETNQINKDIDHIEMNIINLKKKIEFNLYKLPNILLNKVPKGKTTEDNKIIKFYKKENIIQLNNEEYDFIEPHEEIIKKYENNFIFSNISNKIGFGYNILVNDIAKLERALIDFMINTHVNKFLYTYVKAPEIVTKSALFNTGQLPKFEEDLFKITDNYKLLNEDAYLIPTSEVSLLNLFKNSQIDYIHLPIKLVSHSSCFRTEKNNTYGKTSKGLLREHIFQKVELINITDKKTSPFYYKKLIKQSTYILKQLNIPYRLVLLNSIETPYSASICYDIEAWLPSQQRYVEVSSCSNCLDFQARRLNLKYKIKDSNNFCHTINGSGLAVGRVLAIILEQYQIKKKHKNEITKIQVPKVLRKYMNKDIIQVEYN
The following text describes a protein:
Function:
Meiotic protein that localizes to the central element of the synaptonemal complex and is required for chromosome synapsis during meiotic recombination. Required for the appropriate processing of intermediate recombination nodules before crossover formation.
Subcellular Localization:
Chromosome. Note=Component of the central element of the synaptonemal complex. In spermatocytes, detected from zygonema to pachynema and localizes along synapsed lateral elements. Loading to the central element of the synaptonemal complex is dependent on the assembly of the tripartite synaptonemal complex structure that occurs upon synapsis between homologous chromosomes.
Sequence:
MNDSLFVSLDRLLLEFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQSNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSVENDSDEVEERAENFPRTSEIPIFLGTPKAVKAPESLEKIKFPKTPPFEINRNRNAVPEVQTEKESPGLSFLMSYTSRSPGLNLFDSSVFDTEISSDQFNEHYSARNLNPLSSEQEIGNLLEKPEGEDGFTFSFPSDTSTHTFGAGKDDFSFPFSFGQGQNSIPSSSLKGFSSSSQNTTQFTFF