lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
Sequence:
MAEFDKEAYAERERSAASRKTLLKKQELVNSYKERLQKSNGFVIFFNFQGIDAYPLTLLRLDIKDLKGEIVVGKNTLFYRAFSDTVLSDHRDIFVGPTAALFAYEDPVAVTKKLVEFLKETFDKEWEGRIKGGLLDYKYITPEQVKELAELPSKEELIAKLLGVLMAPVTQLAMTLKAVPQKLVLVLKAIEEEKSKGGQ
The following text describes a protein:
Function:
Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells (By similarity).
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein. Nucleus.
Sequence:
MDISETEYNDSDPPVQENGNGKAVVEDEVNDEESNMETVDLGLDDKTSDASSQNVFKNIDNEPSDDQQNVEESENITLEKPEEISAPPTVVSTSQDVSPPPAIESLPPLLEGKELELEDDVTSSLPRLLSKTTLIHSNEEGADETIQRLISSLHSNSPNMDRTQIVDHLFNLLVGGHFDQESKFVIEHVANVDHMLTLLSHCDCDLQNEIWSLFLAVMKKSNRNLEACTRVGLISKNFFLNLVLDLLPEAPPLLADLLVQIIAALVAYSINVKQTKHLLRALRSTKDQWPPNSLKLLHVLKEMPQHDSADVFFSFPGKDQSGIILPPIKTMPYQQGWTFATWLRMEPLNSVTFEKEQPVLYSFRTSKGIGYSCHIFGNCLVVNVEKAKGKEQSRCVKAELGARKWHHIAIAHCYSRWGRSDIKCFIDGQLAETIELSWVVTSTTSWDRCSIGVSADGAVNTAFCGQMGAMYLFAESLSLQQANSLFCLGPAYQSTFKHDSETSLPEGYKKHLFDGHLHSSLVFAYCPKNCHGQLCLFTPPKTAANTYFVQIPHAVMKEGVEVITTHSIHKSLQSVGGIQILLPLFAQIDLPSSHDNTIDGDVCQTLLSLISLLLSSSQSSQQQLFHSKGFLIISSCLQEASPSHLSMKVLEQIIHIAKFLLRCPAGGPLLKHLFDYILFNPKLWIRARPEVQVHLYQYLATDFLANNNFSQMLRRVPTVIEMCHTLKHFYWLALPQTVSDYTVEERPENFATAEIVSIRSAILTFINRIIISSNSPDEEEKARDQEIHTLLNLLATVREDDNLYDVLALVTRLLAEHPAIMIPAIDKNKALGIIFNLLAAPNELIRIPALKILGFFLSRSTLKRKTESMGSQNLFSLIGERLLSHKRTISLPTYNVLLEVLVEQMTPTFTYAAHQPAQPDWKFENPHLLKVIAHVISQCEETESLVQIKKCFLIDIINLCRESKENRRTILQMSVWQDWLIGLAYVFHTSESQNEVSELVWEAFSILLHHALRHEYGGWRVWVDTLAIAHSKVSYEKFKRRLAEAKAKAEKAETGEEAKMEPTPVYRAPEFAWSEVHIRLLADLLSGIERTVEEWKTQEGGISDQCNASENQVFVGNVVHVISQLADSLIMACGGLLPLLASATAPNNDMEIVDPCQQQLPISVAASFLMRFAKLVDTFVLASGVSFSELEQEKNMPAGGVLRQSLRISATVTVRHILASRIQQPDTPRYETNSAKKNQCIMDFVKEALENFSPEGLENVERLVQDSDITRIKGVVYRDMVEENRQAQFLALSVIYLVSVLMVSRYRDILEPPSSPSPFFDSTTTKQENAERGEKLFEFSHNPLFLELPESSSEAVANGKVANDGDHASIKNGSDHSENGADEETEEKGEQGQGDNGGTIAAIKVANSDMKNDGNEYNEEELKKMHQSNGRRPSTLMPPQQTAERRAYLTTKLQTALETCAPLLREMMSDFRGYLQKTLVGTHGQEIMNDTKVLETLRNRNASVIELVMLLCSQEWQTSLQKHAGLAFIELVNEGRLMAHATRDHVLRVANEADFILNRLRAEDVSKHAQFEAESREQLNARYEEYSRCDLLIVSGRLRDSLNATRLLDKMSAILTDGDDSKSGSQFWKLDVWEDDSRRRKRFVPNPYGSRHEEANLPEGEKNEEPEISEQERIRKILKGLFSQRHATTTSTGGQELVDESDIDKWAQEVDPTPSSQSACFSTAAKLIVPGVVVPGTLSVTASDLFFDANESDPNYKKQCAQVLRYCEALHARWNLQEIRAIFLRRYLLQNTALEMFLASRTAIMFAFDSEDTVRKVVYQLPRVGVGVKYGLPQSRKTSLMTPRQLFKHSDMCAKWQKREISNFDYLMFLNTVAGRTFNDLSQYPVFPWILTNYTSDTLDLSVASNFRDLSKPIGALNEARRKFFTDRYASWDDDLVPAFHYGTHYSTPAFTLNWLLRLEPFASMFINLHDGKFDHPDRITHSIKDSWDRCQRDSHDVKELIPELFYLPEMFRNSSKFNLGRRADGTLVDDVVLPPWAESPEHFVLMHRQALESDLVSCQLNQWIDLIFGYKQRGAEAVRATNVFYHLTYEGTVTQKMAETPGQVSAIEQQILSFGQTPSQLLAEAHPPRHSIMTMAPTMFRRHDDDLCMMMKYISNSPVVYLAANTFHQLPHPTVVGVAQNLVFSLNKWDNSYSYGSTQRSALSMDPSNVEGQVALPLTADPQLATAASTTPIARRHLGDAFDQRLQVQCSNFVTTTDSKYIFACGYPDYSFRIVDTDSGRVRQAVYGHGDVVTCIARSETSLFSDCYVVTGSMDCTVVLWHWNGTTGFIAGEYNQPGEVPSPRSILTGHEASISALCVSAEHGLVVSGCEDGVILIHTTASDLLRRIRGHGTVTQLSMSRECILLVLFDSKRMTTYSSTARKLNEVLSEEKIECVTVTRDGEFAVTGAVNGRITIWRMFPLNKLYTYQPLNSAVRSVAVVASHRFILGGLDSGAIVVFNADFNRWHYEYKHRYIQNSSATKPAQASPQK
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
METHCSEILETDTELVNSVNPHETLDRSSPNSPENSANSNKFEGLQMEEEELDSSPVRRYTPYSSYTSHWSQPWGPITNSKPLGSQSTSTAEPDDDEPSDSGWPDGPNKAETTKLVSVGSLWNCHGDEDAKSFMLGAGLANLGNTCFLNSVLQSFIHTVPLIQGLKLNDHATPCDSYLKGFCVICALKELIDALLVSETGVVSPWKFVNNLSYFSSTFHRFQQEDAHEFLQCFLDKLEQCCDVSRPKDSPTLETENFVKQAFGGRLVSKLRCCNCGHCSDTYETLIDLSLEIEDVDSLATALESFTKVEKIEDSETKFTCEKCKEQVSIEKQLVLDKAPSVAALHLKRFKTDGSLVEKIDKYVSFPLELDLHAYADNNQSDNEEMKYDLYAVIRHVGFSYSSGHYYSFIRSAPNEWYKFDDSKVIQVGEDFILSQEAYVLFYAKRGTPWFSDFIEVQKPFIDPSILNTSPKSVLDNTNAVCVTSPRLPNPRALCVKGSHDAASESSPNSLNKVQDSDGKENVQTRSAPGPHGASNILHPKSPEVDKVSFPSILKEDCSTLDPGAPSRPIFITPKTPSRSPSPEIYREDPPENDYHIPRPHLRTADRVSCKKQLQKELEQNMERKQACTLIKKSMRGSRAQQLLAAMAGSQSESSVNKKRRRVDVSPSRDDSSSTSRRRSSLGSVFRTVMTGSLR
The following text describes a protein:
Function:
Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MKIKRFFAKDMKTALLQVKEELGVDAVIMSNKKVAGGVEIVAAVDGDTAPAPAKRYNSQPRHGYNQVSPSVAPTKSRELADDRVSLQSSADSGRSMTQRFANMLKQYSSADEQEHRAENEDSLSALLKRQSENRAPQRNQTQRSQSSSERQRPDSPLGKLLQEDADARRKPRLDPTRYDRKVPEEPMVAVSELESMREEMTSIRRLLEHQVSGLMWQEVERREPLRAMLIKRLERMGVSLEMADQLACYIPEETPPPKAWKALLGLVSDQIPVVKHDILKRGGVVALLGPTGVGKTTTVAKLAARAAMEYGSDNVALVTTDTYRIGAHEQLSIYGRIMGCPVRVAKDSNELADVIYQLRNRRLILVDTAGMGQRDVRLSEQLDTLMQESGETIHSYLVLPATAQRKVLQETIEHFRRIPLSGCIMTKLDECLSLGEFVSVVVQNALPVAYIANGQRVPEDIVIAQPKYMVAKANELLEKSTEDEPHYWTSDSERF
The following text describes a protein:
Function:
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSTKDTNDVKPTSSKSNEISSSGTATPKKTSSVPAKEDRKDTTKKDIANERTSSSKSKDDSEKYVELKNKLIQQILKKQELTRKLTTLEDSIYQKEIDYFEESPLGNIVKGFENFSKTSGGGGANKRKIVYSEDDHIFSLSSVNYIKSLMKRQGHTSNGGSSKDDFDDYEDSVDPTTASAGSKANSIEKNETPSGSSGTPSRKRKARVLED
The following text describes a protein:
Function:
Golgi membrane protein involved in vesicular trafficking and spindle migration.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MPFLTGLQPHNLQQKARLAYRNFREWFDELSILAKIFTSCYLALNFLLFLALIILTPSWIFARLARWAIDLRELTLGPFYLIFFLTLASFPPVIGYGTLTTLCGFTYGWFWGWILASVGCLCGSATSFLLLRKNLPRFQHWLSKQPRFAALRQAVAVKGLPLICLIRLCPFPFTYSNLFFASLTTSCGLQDFMIATLATTPKLLLHVFIGARVFHLSDPSSTHRLDNLTIALNIFYIVAGASLGAAVSYYLYQATMAQAGQISLALDDEARVGGAEGDRLRTLDEEEEEIRRELLGGEAGDSERQWDVEFDDFDQDDEDPQATVNTDGKSSKLQSGT
The following text describes a protein:
Function:
Member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression. One of three clock output pathways. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and involved in clock output. KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it. Phosphotransfer is maximal when KaiC phosphorylation is active during the circadian cycle; this two-component system is activated by fully phosphorylated KaiC. A very robust clock is reconstituted with KaiA, KaiB, KaiC, SasA, CikA and RpaA; output is measured by transcription from an appropriate reporter. In addition to its output function, recruits fold-shifted KaiB (KaiB(fs)) to KaiC to cooperatively form the KaiB(6):KaiC(6) complex (independent of SasA kinase activity); at physiological concentrations increases their association. At higher concentrations SasA and KaiB(fs) compete to bind to KaiC. Mutations that decrease cooperativity nearly phenocopy a deletion mutation; Autophosphorylation and phosphotransfer activities are not essential for clock rhythms in continuous light, but they are essential for adaptation to light/dark cycles.
Domain:
The N-terminus interacts with KaiC, while the C-terminal histidine kinase domain autophosphorylates and is probably responsible for self-oligomerization. The N-terminal domain stimulates the C-terminus to autophosphorylate.
Sequence:
MGESLSPQALAQPLLLQLFVDTRPLSQHIVQRVKNILAAVEATVPISLQVINVADQPQLVEYYRLVVTPALVKIGPGSRQVLSGIDLTDQLANQLPQWLVQQEAFFADREPPEVNIPFTELGQPETPALQQADAFFQLQQQYADLSERTKFLEQVIALVAHDLRNPLTAALLAVDTIQIRSQSFSVATAKEMQGLCSLFDQARSQLREIERMIAEILEATRHSGESLRINPREVVFEPLLQQVLEQLHERWRSKQQQLITDVPGDLPTLYADPDRLRQVLVNLLDNAIKYTPPGGTITIAALHRTSQKVQISISDTGSGIPRDQLSVIFKNLVRLSRDSSQEGYGIGLSVCQRIVQAHFGRIWVASELGQGSTFHFTMPVYRYTMPC
The following text describes a protein:
Function:
May be involved in a redox-related process.
Sequence:
MAPRGRKRKAEAAVVAVAEKREKLANGGEGMEEATVVIEHCTSURVYGRNAAALSQALRLEAPELPVKVNPTKPRRGSFEVTLLRPDGSSAELWTGIKKGPPRKLKFPEPQEVVEELKKYLS
The following text describes a protein:
Function:
Implicated in cellular adhesion.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MNKLFYLFILIASLFILTDASHFRFGTISWQPTTDYRTIKFTSNFAYRTTFFYSSTSSIKVGNLVNVGTLNFGSGVGSVTVSVTVTDFDVKNNWFTGTFTTTKAYPAQNSGTIREYTAIFTSCCRISSLLNNKDASWNITTSVQIDNKNELSMVNWSPVSGMIPIVQVVANKNNNFRVIASDQNVQNADSSALTFSFSKVYTMTQPSGMTIDSKGNCYFLPTQIGLYSTQIYILDSRGAYIVVDFILQSVAEPGTCDPTCSNAGTACNQNSQCKGCTNSGSTTIDTCTTSNYPPDFVSPPTPDDGDTKLFPIGASTSLTFSCKTIMSGRSTTIQTANLPVGVTTKTPVTGATSNTTITWTPTTANTGSYVVSLVCSDSTGLTSSVRSFTILVAKPDCGNGGYTESGVCKCVDNWDPASKCFECKDGYYGENCVAVPPCVNGVPNSGINGDGKCLCSNGWTGADCSISSSQSCKDLSNSNTSISYSNPSFVNPTKVQVYLTSTPNYEVPTIVSIPNPINNLDVYVLVDANLASTTAFGYIKSGMSTFVSNIENICETAQFGIGYFSDYTPSPISFSPSQVMGSPIAAAIGLYKPATYSTTSNGNSLLAATDAASASVGWNSGSFKVIVIITDSDHSSSSAQITAFTNKFIGKSIVPVVVSFGASSMTNWNSALTSAGFGSVVTASGTSASDWSAKANTGVKNVLSKIVYKSDPTATGSSFVSSVPSTVTVSSSSSTQQTVNGLKLSLPSGTTIVSPVATISAMGYGQTDISINYNRPPVATSGSFSVNQNSLATFKLTGTDPDANILQFKFTTFLTANAGVITDSNGKDVSKQQSNYYAASEIFTYTPFENYLASNTIRFVAFDGCVESNTYATISITINKVNQLPECSSISSTITTTLNTQSTFSMTATDFEDASPFLQFTKPTDLTAYGTFTYKGASITSSTKITTGDSVIFTQTVNPKNDATVTLEFRAIDTSNAFSQASCSVSFKIQHANVAPVSSSTSPISVIPRGSVSLTLVSTDSDSTKALFTITAIKNGNNGNFYTCSTNDCSCTSGSSDSTIISLKDQFSGISYSSTKANKLICFTNGEPSAISNYASISFTSTDDEGLESNTVSVVVNIVGDRANVAPVVTKIQDYSVYQDYLDSDAHVVTGTDADIDDYNPPNVNNLIAIITTPPSNGILVTVQNGNNVATQGNAPFTHYYRPNPGFKGTDSYSYQVMDTFKETSSVESTTVTVNPINHKPTLTVNSYSFTSQSGAGETQTLVTYDFDGDNVLCSVQAAPKQISMYDSENELITTLPKSLSSNSYSFKLLDASKISPTPFSSFSDSFIISCKDDSKLTTPYGVLSTGNVTGFVQFTYINTPPTTKGIQVELDQDTTEPFTFNGTDIESPSDLKAKIYALPANGQLLNGNVVLTSKLIGEETYELDALSYKPNAGLSNWNTIDNIGPLDSIPYSVVDQQGLVSDSDVVTFSVRPRNPPVYTGADVIDVLQNTRYPLNVQGKVGNGGSEVNIQVLKFSGRGTLSIAHSMGSEGTMDTEITSYPNSQTGSTSYNFAYMPPHNEYGNDFDFIEFKLFDGDLYSELYTITVNVIHVNQPPTIQLISYKVLDDTSKDNGEVLFDSTYIVNMNINTSVLIKYTGSDVDVDQVTPLLSTVTTALRGTLYTKDETVPDLKGSIIDRNHTTVEQSSDGYYYVVYSPVPDSSGNSYVRIPFFMTDNGGLDSPTLTAVINVNRYNIPPFVLAGNKTYSTTTKLALSVENVQFDDPDSGKSNNVSIVVSIVGENDENVASLEDIKISLKRMQNCELHTSLASISCLDTKSALNESIQTITVNAVTAGNYRLKLFVDDLGYNAPSAIRAQSHMNATGYVDVTFEEAETTTQTNDNKTVLTGAIAGAAAGTALIAAAAWRLLRKAAPPTDTFFSEAAFLGDGVSSNPLYEQSASAAENPLYQSASDTTD
The following text describes a protein:
Function:
Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. It is required for pilus biogenesis (By similarity).
Subcellular Localization:
Periplasm.
Sequence:
MKKIWLALAGMVLAFSASAAQISDGKQYITLDKPVAGEPQVLEFFSFYCPHCYQFEEVLHVSDNVKKKLPEGTKMTKYHVEFLGPLGKELTQAWAVAMALGVEDKVTVPLFEAVQKTQTVQSAADIRKVFVDAGVKGEDYDAAWNSFVVKSLVAQQEKAAADLQLQGVPAMFVNGKYQINPQGMDTSSMDVFVQQYADTVKYLVDKK
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Sequence:
MENKVILGYWAIRGLAQPLRFFLEYIELPYEDKRYTNPEEWFGKDDQTFNSPFTNLPYLKDGDHTVFESDAIYYYLAHKVNKPELLGKDAKQQTMVATIRGSVGDFRASFFQWVYGGKETAEAKKEAMLKETGEFFKIYNTTLESSTWLTGDTITYVDFLVWEYVDEFLVLAPEVITSKPKLVEFHKRISEFPQIKKYLESPNYIKRPYNWEIQAVFY
The following text describes a protein:
Function:
Might play a role in the development of cardiac outflow tract.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MEVDKHSVWDSLKEKTRPLIQNLSIRKSKKSSLKVDISKRRKLGQRMSLSVPNMKEVGCTTQEENDYIETQVSACSVSNRHSSPMLFHSRQREYVKQSKETSTWVQEDSVHMEIIVTEYDGLDCSQSGPKEDTCEDNILDLLQKECLGDDTSDQKPEERSGSIDLNSSLASQLSAELSGLENYDCLSYLLTIHLKEGRNLVIRDRSGTSDPYVKFKLNKKTLYKSKVIYKNLNPVWDETFVLPIQSLDQKLHIKVYDRDLTTDDFMGSAFLELQGLELNKTTEKIFRLEDPNSLEEDMGIILADVSLSVRRRDPKDTGRSSRRRLGASKATSLQGVQLSESLRKNQLWNGTLSITLLEGRNLSEGLTLDSFVRFKLGDQKYRSKTLCKSAHPQWRERFDFHYFSERMGILDIEVWGKDNRKHEELVGMCKVDIAGLPHQQNNRLVLPLENNQGSIHMMIALTPCDGVSISDLCVCPLVDPAERKQMDKKYNIKSSFQNLKDIGFLQVKVLKAEDLLAADFSGKSDPFCVLEVGNDRLQTHTVYKNLNPEWNKVFTFPIKDIHDVLDVTVFDEDGDKPPDFLGKVAIPLLSVKHGQQVAYLLKNKDLGSTSKGVLYLEIDIIFNPVRAGIRTFIPRERRFVEENPKFSKKILSRNIYRVKKITMAIWNTVQFIKSCFQWESKKKSLIAFLVFLLTVWNLELYMVPLFLLMLFTYNFTMITTGKVNTQDNLEGMDIGDDEEDDEKESERKSIRDRIQMIQDIVITVQNVLEELACFGERIKNTFNWSVPFLSLLACFILSTATVILYFIPLRYIVLIWGINKFTKKLRNPYALDNNEFLDFLSRVPSDVQKVQYAELKPCSNQGALRKKRS
The following text describes a protein:
Function:
Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore.
Subcellular Localization:
Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Nucleus.
Sequence:
MHLKMVQLLISVLHVLYIVFCGLVKKPCTLACPLKTILKNFSKTTALFLKNIIVYVRKMEVFQELRKTSARLECDHCNFRGTDYENVQIHMGTIHPEFCDEMDAGGLGKMIFYQKSAKLFHCHKCFFTSKMYSNVYYHITAKHSAAEKWNEKPKNQFNKEGEPVKSPPLPEHQKTASSSAELLKPAPALSIETQKLGPVASPESPEPAPLPSLDSQKPGPVVSPEPQTPSLPSPEPPKPAPVSSPELPKPAPLVSESQKLVPVPSPEPQKLAPVSPEPIKATLTNPKPQKHSHFPETLVPPSAPSPESPVLAASPEPWGPSPTASPESRKPAQTVSPEPRKLSPSVSPEPWKLFSAVSSEPRRPAPSVSPGSWKPGPPGSPRSWKSSPSAASGPWKPAKPAPSVSPGPWKPTPSMSSASWKSSSVSSGSWKSPPASPESWKSGPPELRKTATTLSPEHWKTVPPESPELRKPGPTLSPEIRSPAGSPELRKPSGSPEIWKFSPDQRKTSPASVDYPESQKSSRGGSPDLWKSSFFIEPQKPVFPEIRKPGPSGPSESPKAASDIWKPVLSVSTEPRKPSLFSEPTKTAPPASPEPRKRALFPEPRKHALFPELPKSAIFSESQKVVELGDEPQADAIDDQKCDVLVQEELMATPKKLLEDTLFPSSKKLKKDSQENSDAELSSSECIKADLDAVDGKGQESSSDQEQVDVESIDFSKENKMDITSPEQSKNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMKKGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGFKKHLTHCQSRHNEEANKKLMEALEPPLEEQQI
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42.
Subcellular Localization:
Nucleus.
Sequence:
MSDEASKSLLKFFDDNECWIHPEVEIRTSKLGGTGVFAKKDLDAGDIVLKVPKSACLSPRTCGIANLLDEHDLDNIAGLLVAFLYERSLGDQSPWHEFFESLKPVIADVPEIPKFWSNDEDRALLSGTEVEEIGGLETGEDEEVYQELIVPFFEDNGKLINLECPSFDEFKKLVVVIASRAFEVDQFRELCLVPGACLFNHSDDPDLHFQTDFGVCPVCGDVYCDHDVEEQEHEHSGSCCSGGDHHHGHDDEEDDWSDESVDGDDDEEREEEMEEVESGDEDEEMEDGETEEDEEEGDEHDEDEEEEDSEICDMQLQNDIKAGKEIFNTYGDLPNSMLLARYGFAIWNNSQEVISLWKEAMAYAKKAGRMDRLKMLRKRDPELSEKVFVAYSDGDVNKIEWGPCVNAMLTLLLMTDQEYKKKVCSRRLDKDINKAKKLLLNARLKRYEDGGMTSEEYKKVLPKVEGTKKAAIVIRGTEKKVIETALKTLK
The following text describes a protein:
Function:
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein.
Sequence:
MSKVHNSEYIKELVVDNTSYKIYDINKAASDIGLPLKKLPYSLRVLLENVLRTNGNKENLLVFKEWLKTKKSNTEIDFMPARVLMQDFTGVPAIVDLAAMRDAMQKIGCNPLKINPLIPVDLVIDHSVSVDSYGNKESFDQNVHMEMKRNIERYQFLKWGQQAFNNFKVVPPGTGICHQVNLEFLSQVVWHNDGTAYPDSLVGTDSHTTMVNGLSVLGWGVGGIEAESAMLGQPITMIIPEVIGVKLIGKLAGMATATDLVLTITEILRRKKVVGKFVEFFGNGLRNLTISDRATISNMSPEYGATCGFFPIDQETLKYLEVTGREITQIKLVEKYAIEQNLWYNCEDTQEYTEVLELDLSTVYSSLAGPKRPQDRVNLNCVASNFQNELPYFALANKDIDKKYAVANQNYAIGNGDVVIAAITSCTNTSNPSVMIGAALLAKKALEHGLNVKPWVKTSLAPGSKVVTEYLKLSGLDKYLDALGFNLVGYGCTTCIGNSGSLNPEIENTINKNRLVVASVLSGNRNFEGRINPLTKASYLASPILVVAYALSGTLNIDLTNTPIGANIYLKDIWPSQKEIDEVIANSINSSMFIEKYADVFNGTKEWRDLQITTGTNYNWDKNSTYINNPPYFDNIGSEHSIKDIKSARILAIFGDSITTDHISPAGSISKNSPAAKYLIKHHIEPLDFNSYGSRRGNHEVMMRGTFANIRIKNEMCNGVEGGFTINQLSGVQQTIYDTAMDYKAHDIPLVIFAGKEYGSGSSRDWAAKGPGLLGIKAVIAESFERIHRSNLVGMGILPLTFTGKNTRLNLKLDGSEIIDLIGLSENIKPYNLVKCVIKKQTNEISTIDLILQIFTENEINYIKHGSIMQFVVESLKG
The following text describes a protein:
Function:
Constitutive protein of the cell wall. Antigen target of host humoral immune response.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MKFTTGFFTLALAYSAFAEPIPKAKRALSDYTGVFDAIGAQVATVSSTVASYVAGSTSGSAVQDASTELVTIINDGAASVAGFDSLTSLEALQLVAPIQDLTGDISDLIDAVIAAEPNFVADGLDGDVLTSLQDQKAAAEGLRDAITPKVPAALEDIANELSEGIVAEIDRGIAAYSD
The following text describes a protein:
Function:
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
Sequence:
MLTQEDVLNALKTIIYPNFEKDIVSFGFVKNITLHDDQLGLLIEIPSSSEETSAILRENISKAMQEKGVKALNLDIKTPPKPQAPKPTTKNLAKNIKHVVMISSGKGGVGKSTTSVNLSIALANLNQKVGLLDADVYGPNIPRMMGLQSADVIMDPSGKKLIPLKAFGVSVMSMGLLYDEGQSLIWRGPMLMRAIEQMLSDIIWGDLDVLVVDMPPGTGDAQLTLAQAVPLSAGITVTTPQIVSLDDAKRSLDMFKKLHIPIAGIVENMGSFVCEHCKKESEIFGSNSMSELLEAYHTQILAKLPLEPKVRLGGDRGEPIVISHPNSVSAKIFEKMAQDLSAFLERVKKEKLADNKDIQPTQTHACSH
The following text describes a protein:
Function:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR (By similarity).
Subcellular Localization:
Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine. Note=In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex (By similarity). In neurons, enriched in dendritic spines (By similarity).
Domain:
The PDZ domain participates in protein-protein interaction, and is responsible for targeting nNos to synaptic membranes. Mediates interaction with VAC14.
Sequence:
MEEHVFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNGRPLVDLSYDSALEVLRGVASETHVVLILRGPEGFTTNLETTFTGDGTPKTIRVTQPLGAPTKAVDLSHQPPSAGKEQPRPVDGAAGPGSWPQPTQGHGQEAGSPSRANGLAPRTSSQDPAKKSGWAGLQGSGDKNELLKEIEPVLTLLAGGSKAVDGGGPAKAETRDTGVQVDRDFDAKSHKPLPLGVENDRVFSDLWGKGSAPVVLNNPYSEKEQPPASGKQSPTKNGSPSKCPRFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMFPSQHTRRPEDIRTKEQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRSRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPCFEYQPDPWNTHVWKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFRCALMEMRHPNSLQEERKSYKVRFNSVSSYSDSRKSSGDGPDVRDHFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPGLTQGLSSVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPANQMVKVELLEERNTALGVISNWKDEPRLPPCTVFQAFKYYLDITTPPTPLQLQQFASLASNEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPIHHGVCSSWLNRIPADEVVPCFVRGAPSFRLPRNPQVPCILVGPGTAFAPFRSFWQQRQFDIQHKGMSPCPMVLVFGCRQSKIDHIYREEALQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAEQVYRALKEQGGHIYVCGDVTMAADVLKAVQRIMAQQGKLSAEDAGVFISRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
The following text describes a protein:
Function:
This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MARPLSDRTPGPLLLGGPAGAPPGGGALLGLRSLLQGNSKPKEPASCLLKEKERKATLPSAPVPGPVLETAGPADAPTGAVSGGGSPRGRSGPVAGPSLFAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGLSPAPSPARTPAPSPGPGSCSSSSPRSSPGHAPARATLGAAGGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEELKPQPIMKKARKVQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQEVVAVRQELSHYRAVLSRYQAQHGTL
The following text describes a protein:
Function:
Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and may act by promoting the disassembly of the MCM complex from chromatin (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MPCAMELPSTPDELAAQQADSAALKDLLKDPSRWHSIPLLNYTPLHKLKDQTLVRFRGMIQDMMDPEIYLERYEVKSADGSKRVQEGKYRDCLKIANGEVIDYNADGNVHGERRTMFVVSVPGLNDWSKEHEKLCCPQIDLASLGQSPSSAKKRTIVGEEEAMDVDVASETTFKRPCLKEIQKDSEPVGASKSSVLGSDYLINSPLPDRPSMACMVKVYEEFDTYQLNSLVDFVGFLSVDASLDAATLEIDDCENLSELQAAHPSPFLIPRLHAFGVQVLPHANPLLDKSLRQPTEICEETYPTHLAVHKDLRMLLKLCLFDDDLAAEYLLSHLISTVYSRSEMQSIGKFALNLCNLPKNCEAYATKLYQILELLLPASHYMPMTLVTLNTAAFAPKKDYETNKLVSGVLQLAPHTHLVLDETCMQQGKLEANGVHAVQHLAHLINNQELKCDFQYYQIDYQANIPVLVLSEGRSMLPSDFVLPINADSKAVELVDESLKAAHHYLQPSRLQQFRKYLTTARTSGFNVSEEHTEMIQQDFVDMRKANVKSNADDLHGLLVLSRLLGIARGKDTLDKETWQLATEFEAKRRQRIQSLPKSSAQLRN
The following text describes a protein:
Function:
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
Subcellular Localization:
Nucleus.
Sequence:
MIIYLRTDGYYSGKEKISIVNENVRSKLIRCRSYVVDKYSDKQLLFLNGKVLNVHKSFSENNIKEGDVIECSMFPLATVIIHYLERKIIEQCKQMKTSEPQSYFNMGTLRKNLRMVSDNFDKIKSYQSDGLNGLKLLFKDNGISHNEIQEIYFNYETFDMPQKDPLDHFISRIYNKTTSTTSIPIALPLTKKPIINNNNDDSGIIVNLDDNNSDDERTPSSQSFSTPKKQQQQQQQQQQQQQQQQQQQQQQSYSTPQKQQAQPQQQSYSTPQKQQTQVQQQSYSTPQKQQTPQQQQTQVQQQSYSIPQKQQAQVQQQSYSTPQKQQTPQQQQAQVQQQSYSTPQKQPTPQVQQQSYSSTPQKNTSFELDSYFDVDNELEVFSQPQTPSQQSDKSKTVISPISTPKSKISLNDFSLISPILKHSTNKSDLKKNNSFDKDIDFFENNFNINVNSLNNSLGSSQNSATISNSSSQNSITVSPNNSSNCINNDNNNNNNNNNNNNNNISNNSLGKRPLSLFTSTTSNKKQTTTTTTTTTTTPTSTTPTNKKNITDYFLDDSEDEDIFVSSLSSQSSMSNKSNSSLNNSNNNNNNNNNNNNNNNNNNNNNNNCKGGNSDLDFLDDFDFGYEDEEFMFDEYSIKKSRNELSSSSSQPFINTCITTSTKITSTNSNKLLSKSESSLDTLLFKKPKTPQKKQKHISSPLLHSSQPIPLTMDSSLSKDIKNSLIPIKTQPITTTTSTTTTNSNTNTTNNNDNSIIKIEKPFKRLTNGSIPPILILNAPLPNRFKFKSNLLDFKPTFQYPPFSLLISLSELKTSKGIKTVSVKEIMEGGQNYTTLCDTRNPEFSIELKTPKFAITNTLMVNDCLELEEGKEDSFYITDLGYRYARIFQDYHNDYLEFCKVNSLRINVAQNDVTIVIDSSEKLSNEFKRNFNEMGINSINTFQLPSADFIFLKKNSNNNNNINNNKNHSFFNNNNIYDIDSGGNALMFPYIIERKTWKDLSASEKDGRNARQMTKMKAYGKLKGRFYLVEGEPSNYNSEYQVTTIEELKKRLDLLTTADNFTIIKTNSPYDTTRQIAIIAKMLSTDPILSNPSNLLLYNDFKDAVTKSNYEKYHQNNNININNINNNINNNNPIMELALTQMADQTDLSVIEHSKSKSEKIWFQMTIDQFKEYILSSDYRDQIRNTMNNNEYSSKRKILIINEFNKFKVQQQKSHNQLFQDYLYQRYNNRSVNNISKSFRNEKSLLLSDYLDNDIINHYLLQLILHFNLQIFIQFHDSERGNVESFSSFSKSIEKAIQLNQDYQHNLKFKTIFAKTIPVFRSIKQQRLEDSINYRNELENFNNNNNNNNNNNNNNNNNNNNNNKNNNNNNKNQFSYIDDIIDLDDD