lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in a subset of tRNA. Selectively mediates Gm18 methylation of tRNAGln-TTG/CTG and tRNASer-TGA/GCT. Gm18 modification can enhance the stability of modified tRNAs.
Sequence:
INIINFLKNIFKENNSNNSNINHEINIEQNQLLVSSLFLLTPNLNKNNILKEIFNYLNNNENNNNNNFHIFLLSIVYSIIKYNNNNNNNIDNNEIIYNIIKFYSNQIINENNINNNSVNENNIKIISKLISKIQNLIFNNEIYLMINKLIDGVNNNNSNSNKFGLQLVNGILNDGDISIKDKERMCIEFYPTLIPTVIENLENSTIINQYTKQQSLFILSKLLLDKENVEIISKNEKLLNLYYGSWLQLLWSAIIKQKDINEKLKLCFFFHQCYFDCLIFNLKSKKLNDEGTFNIIKKVDYWNILFESLIDKDSLPRKQAIHLLKNTVSLPSMLWKESLPKGWEQKQWNLFFSLYECFDETKSHLFVPVWVQIHNLINASNERDNFTHFKEPSSIYFWIRILYFRGFNHINVNIKKRVIVDALADQSILKHLHQIDFVEFQQPLLKALDTFEITVNYESERSKDLVERLSNYLKVTVKSNLELEQLLQFISKSTQEVKTILLFTSILSKQALESHLSASSNILESIRYILVSHPIQNSNTQLYQNMFELLKSLDISNEQLSFSQISKIISMIPRELIDNDFKNHWMKSKGNWFIINLKEATEKTITSESNTLSNNSSSSSFENEKENLIALSRVLSICSNAEIQDYIENTIIPYINDSEKVNRDQQMKLLLLINSILEELQEKHWIKVSNQIEPIKFTLIKLIKQYIVEKTYTQDNYNTTLTKEESEKIIDQFKMFEMAIKLIKKLPHSAEFTQLSNDMKNYILNDSTSLDLKGITVVLLVWIQCKQQPFHQPQQPIDPTNTNNINNEVLFNKLLTLEPKYKFDSTISYILPKFIQFKWTSIHSILFSFASNTKYSQEMTFDLALSALDNATGSTLIPIFECLSIVISSPSSTEILNNEHLMEQLFKQSYLAFSDSNRKPNNLCIAFSNLLFNSILFENSVTIPLVKSYLKQTLEDLGGSVRISCGLLSHCCAIWSKKINTLPIFLNEIIDLCLLTSEDKLVLEDSNENNEEQSSDSFKLFNNHGYIIRWFVSQLTSNECKPFVETLILELLQLNFKSEFSKREYSQHSRTNKMKCKLWRTLCSLTHIIQFNQDNIELYEKISNLMWNTLELKNHSNVRYLIQLFIINILVKSPNIKETNQKLVTKMEDSINSDYQISASLIIISSTFLYYLLNNYQDSYEQMVINLFKTLLPWSTDFHHAVRTTSQLAIYTIINKKFKILEQFNESELIKSIFNYLEINKIQKRLREKQTLFVESDDPLKKTLAENILSDNSIGNTGGDDEDDEGESNKQQQEDDDYSNLSVIDDAIIPMSLLDISKKLIKDFQVSFQNNQNQHSAAVPQPTTEQKEHIQINNSNDDEDDEILDFQRRITPWQWINKLEEHHQINNTNNSNNNNNKKNKRQSMIIVGTFIENTPNLAGLIRTCEIFNVEEVAIPNLKLLNDPQFQRVSVSAEKLVPIIEITKPNLLDYLKLKKKEGYSILGVEQTSQSKNLSSFQFPEKCLLLLGQEQNGIPANYLTIVDYCVEIPQLGQIRSLNVHVSASIVIWEYTQQQILQQQK
The following text describes a protein:
Function:
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). May play a role in intracellular vesicle trafficking (By similarity).
Sequence:
MNPKDKRVNFGSMEPLIRDIGTVYEFYFDQNTFIESEIKTFLKEFETKRGDRDLYSLSQQTINANNTIVNINRSIHQSSQFLENINNNLNQINSKLSTQVENESIHQEQRNNDRLNKFELELVEKKSIEDSFNQRKSQIENDFNEKASVLRDKYQIVL
The following text describes a protein:
Function:
Aquaglyceroporin that may modulate the water content and osmolytes during anhydrobiosis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKPNSVARVWSRICNCRLESRSCRDVLAEFLGTLILTLIGDSVLASLTASRLGYFGIAAGPLASAGKFKWAKVLPYIAAQYLGAFAAAGLIFLLYQDALYKVDGGMRVVYGPNATASVFSCFPAPEVRTLTCLLDQVVSTAVLLVSICAIVDPKNMAVLKGHQPLLIGFAVAACMYAFSYNCGNPLNPARDLAPRIFTAMAGWGCDVFSIRGYNWFWVPVVGPHVGGVVGVWIYKFAVENHWATDAAAVVGKTPEEEHDYEGKRRLLRQDTHHIEADIAS
The following text describes a protein:
Function:
Modulates RecA activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MHSRPERRRDPLSTALDILSRRDHSEAELARKLRSRGIDAGEIDRIVARLREFGYLNDRRVACRLAESALAQGKMVGARLRVELRRRGIPPELAEEALAQAAAGCDERALVGDLLARKFPGFDPAVADPREKRRVVGWFQRRGFGLSAILEALRCPVDE
The following text describes a protein:
Function:
Involved in protein export. Participates in an early event of protein translocation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFTVLLVIYLLAAVAIIGLVLIQQGKGADMGASFGAGASNTVFGASGSGNFLTRMTAIFATVFFVISLVLGNMSTHKTESQWVDPSQGQVIQQAGDSVSEAPAKSSDEIPQ
The following text describes a protein:
Function:
Methylates MRF1 on 'Gln-287' using S-adenosyl L-methionine as methyl donor.
Miscellaneous:
MISCELLANEOUS: Present with 13200 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MPRISTSLIRKASRIRPGLHLLLPECRTLEQAKLEYKWLTEELPPDKSIRWACLQRYKHVPLQYILRSQPFGALDIVCKPGVLIPRWETEEWVMAIIRALNNSMLSRHTIPLHICDTFTGTGCIALALSHGIANCTFTAIDVSTRAIKLVKENMLKNKVSGGKLVQHNILSSKASDEYPSHIDILTGNPPYIRKRDFNRDVKTSVKLFEPRLALVGELECYINLVNYWLPKTDSFFYEIGDVEQFNYVERRIKEDSYLSRIWSIGLKYDSNGKARVVYGFKATPKGRILHQIFASFGTIRHLATALSGHKANCN
The following text describes a protein:
Function:
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MPRMERHQFCSVLLILILLTLVSLTLTGWAWTIPDCIIADSLLFPNLSYYIPFCTSAPGLHLLASCSNVKNLNQTLKRVPRNTEVLCLQGMVPTLPAKAFIRFHSLQLLRLQLRTTSVTSRTFQGLDQLQYLFFDHHAPCCLSLFLSPNCFESLRSLSSLSFQGYCLTYSQSIYLPTSLRHLTLRNSCLTKFQDLQRLFPDLLLSTSSTPNIKPGAPFLETLDLSYNLQLKQAGVRDLYGLTLHSLILDGTPLKALDLTDSGLLHLHFLSLVGTGIEKVPASLTGYSELRALDLGKNQIQNILENGEIPGYKALEFLSLHDNHLQTLPTRFLHTLPQLQKLNLSMNKLGPILELPEGLFSTNLKVLDLSYNQLCDVPHGALSLLSQLQELWLSGNNISSLSNESLQGLRQLRTLDLSWNQIKVLKPGWLSHLPALTTLNLLGTYLEYILGIQLQGPKMLRHLQLGSYPILDIYPPWPPTLLSLEIQAESCIQFMIHSGQPFLFLENLTLETSILLLKPDNITIHFPSLRRLTLRGYSFIFSTSQLQRFFPQQLPLLEHFFIWCENSYAVDLYLFGMPRLRVLELGYLNFFYESSTMKLEMLLKEVPQLQVLALSHLNLRNLSVSSFKSLQDLKLLLFNSERALEMNSNLQEFIPQMPQYVYFSDVTFTCQCEASWLESWATRAPNTFVYGLEKSICIANASDYSKTLLFSFLATNCPHGTEFWGFLTSFILLLLLIILPLISCPKWSWLHHLWTLFHTCWWKLCGHRLRGQFNYDVFISYCEEDQAWVLEELVPVLEKAPPEGEGLRLCLPARDFGIGNDRMESMIASMGKSRATLCVLTGQALASPWCNLELRLATYHLVARPGTTHLLLLFLEPLDRQRLHSYHRLSRWLQKEDYFDLSQGKVEWNSFCEQLKRRLSKAGQERD
The following text describes a protein:
Function:
May be a cell surface adhesion protein.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MELAVALLAAALSLTVPLAGAHRPLADEVGARAHLTEILTPDRPFQTFLRYLQQTNLVEVFEKQAYRTHHGITLFAPADRAFAAVHPSVLSGLKKHQLKNLMMYHALAKHYALKEFDGLSRVSQVTTFAGGMYTVNVTCDPGAIRVQSRWAAAKILGTVYGVAPMAVYEIDRVLLPEAIFRVQPPVEAALPDAEPAASAPGAKGGNATTTPGDKAEGERSACRAAGRLDSYVAAMALCAASLVAAL
The following text describes a protein:
Function:
Substrate-recognition component of the SCF(Met30) complex, an E3 ubiquitin ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Negatively regulates sulfur amino acids biosynthesis genes expression. Controls cell cycle function (being required for the G1/S transition and M-phase but not the S-phase), sulfur metabolism, and methionine biosynthesis as part of the SCF(Met30) complex. Required for the efficient binding of CDC45 and MCM proteins to origins of replication. Required for efficient expression of G1 cyclins. The SCF(Met30) complex catalyzes ubiquitination and degradation of the Cdk-inhibitory kinase SWE1. Involved in the S-adenosylmethionine (AdoMet)-mediated inhibition of the transcription function of MET4. The SCF(Met30) complex mediates ubiquitination and subsequent degradation of MET4 and the cellular response to cadmium. The SCF(Met30) complex acts as an inhibitor of autophagy by promoting ubiquitination and degradation of ATG9 in normal conditions.
Miscellaneous:
MISCELLANEOUS: Present with 217 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MRRERQRMMSFEDKDKDDLDNSNSNNSSEMTDTAMMPPLKRLLITGSSDDLAQGSSGKKKMTMATRSPSSSPDLATNDSGTRVQPLPEYNFTKFCYRHNPDIQFSPTHTACYKQDLKRTQEINANIAKLPLQEQSDIHHIISKYSNSNDKIRKLILDGILSTSCFPQLSYISSLVTHMIKIDFISILPQELSLKILSYLDCQSLCNATRVCRKWQKLADDDRVWYHMCEQHIDRKCPNCGWGLPLLHMKRARIQQNSTGSSSNADIQTQTTRPWKVIYRERFKVESNWRKGHCRIQEFKGHMDGVLTLQFNYRLLFTGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYFDDRKLITGSLDKTIRVWNYITGECISTYRGHSDSVLSVDSYQKVIVSGSADKTVKVWHVESRTCYTLRGHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNSCLKVFRGHVGQVQKIIPLTIKDVENLATDNTSDGSSPQDDPTMTDGADESDTPSNEQETVLDENIPYPTHLLSCGLDNTIKLWDVKTGKCIRTQFGHVEGVWDIAADNFRIISGSHDGSIKVWDLQSGKCMHTFNGRRLQRETQHTQTQSLGDKVAPIACVCIGDSECFSGDEFGCVKMYKFDLND
The following text describes a protein:
Function:
Involved in biofilm formation.
Sequence:
MNDRFERLLKSRIGLDASSVGSAVIERAVRQRMSGLALHDEDEYWMRLNGSPGEVQALIEAVVVPETWFFRYPESFTTLARLAFERLPSLGGGRALRILSLPCSTGEEPYSIVMALLDAGLSEYLFEVDALDVSARVIERASLGVYGRNSFRGDELGFRDRHFSEVAEGYQLAEQVRRKVRFRCGNLLDPGLLAGEAPYDFVFCRNLLIYFDRPTQSEVVEVLKRLLRPDGAMFIGPAEASLLSQHGMQPIGVPLSFVFRRTSEAPRGARPKAVSDGARPVVAAAVERASIRPSPPPPAKPRQRLSSLVPPASGQPLASPVGEFDEIARLADAGQHREARAACERQLAARGPSATVFYWLGLLSDVAGQEQEAQDFYRKALYLEPQHAEALAHLAALLAARGDHAGARRLQQRAARGVNKDG
The following text describes a protein:
Function:
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MDAIMPICKTVTPSPGLFFGKTREIRSSKCSFMVGNKVNFLRQRAQGAQVSFKSRKHGGALHATCRAEKILVANRGEIAVRIIRTAHEMGIPCVAVYSTIDKDALHVKLADESVCIGEAASSQSYLVVPNVLSAAISRKCTMLHPGYGFLAENASFVEMCREHGINFIGPKPDSIRVMGDKSTARDTMKKAGVPTVPGSDGLLESTEEGIRLADEIGFPVMIKATAGGGGRGMRLAKEPEEFVKLLQQAKSEAAAAFGNDGVYLEKYIQNPRHIEFQVLADKYGNVVHFGERDCSIQRRNQKLLEEAPSPALTPELRKAMGDAAVAAAASIGYIGVGTVEFLLDERGTFYFMEMNTRIQVEHPVTEMISSVDLIEEQIRVAMGEKLRYSQDEIVLRGHSIECRINAEDAFKGFRPGPGRITAYLPSGGPFVRMDSHVYPDYVVPPNYDSLLGKLIVWAPTREKAIERMKRALDDTIITGVPTTIEYHKLILDIEDFKNGKVDTAFIPKHEEELAAPQHLVLKN
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MDTSSEMLVRFGRRCGRAKESTEIRNSEEDQVLYLPLLPSKVDLQQVTIIPHDEWKRIQDSLDRLTREAACLRAERKAKKEMHLRSQEVVKHWTNTYAGMKEQKLEAKKKRDEEIEAERQILDLEEEIYKQGKRKKAIENAKQYQFYQTERVKNFHSGLLLSRVMKERDAQIEFRKSKIKSDKKWEEQLKLNIEKAFKEEQEKAEKRHRERVALAKDHLKQIKEHEEEEERRKKYEEKDAEEIKRQNALYEIEMRKKLEKKREEMHESRRRFLEHMQDKHIIKAVEQQQQEEEDEKMRKFIKAKKRLIQMGKEKEAETHRLMEKRRERIHNFLSELLKEKLDNEDMIIARDIAEAEAEWEKREREKDEKNKAELKTIAEYRAIVMKNKEEEERQRKIEAKEQLLAVMKADQIFWEHEKEKKCKADKEHQEVQDAHIQQMAKNKFNAKQAKQAELDYCRLTEALVAEKEKEFQDYAREVIELESETTNKYIYPLVKAVQEGPGGGRGPVFVDRGGLRPSYQANDVTGVQLPFYNSQGPKYNFQKSKRRLGFTW
The following text describes a protein:
Function:
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine polymers in chitin to form chitosan and acetate. May play a role in evasion of the host immune response; plant chitinases liberate chitin molecules from the fungal cell wall which act as elicitors of the plant immune response, deacetylation of the liberated chitin neutralizes elicitor activity.
Subcellular Localization:
Secreted.
Sequence:
MLAPLFAALLAGAATASPIQERQSSVPVGTIITACTVPNTFALTFDDGPFAYTSELLDLLSSNGVKATFFLNGQNWGSIYDYTSVVTRMDAEGHQIGSHTWSHADLATLDAAGITSQMTQLETALTSILGKVPTYMRPPYFSTNALALSTLGGLGYHVINANIDTLDYEHDDDTIGVAFTNFQNGLASGGTVSLMHDVHAQTVHVLVQEAINAIKAKGLTPVTVGTCLGDASANWYKSGGGSGTTPPPATGGPSPDDTCGGSNGYVCQNSQCCSQWGWCGTTSEYCAAGCQAAYGPCT
The following text describes a protein:
Function:
Non-catalytic component of the proteasome.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTSQDPEEMDTSRSWRMEMFSRVTKMEPLLEVQSGFWAGGPSPGQFYRIPPISGAVLGPDSIACAGPITRTQNPMVTGTSVLGVKFDGGVVIAADMLGSYGSLARFRNISRIMRVNNNTMLGASGDYADFQYVKQVIDQMVIDEELLGDGHSYSPKAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPTLATGYGAYLAQPLMREVLERCMRVLYYRDARSYNRFEIATVTEKGVEVEGPLSAETNWDIAHLISGFE
The following text describes a protein:
Function:
Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MADIHGLVDRLEKAVSKLESLAAGSGGDASSADTAVYVQAYDNLINGPVAEFMKKSKEIGGDVEKQADMFMSGIQLQRGILVMASQYQQPAEKDLVAILAPLSGKIQTVQEFREKNRGSKLFNHLSSLSESVPALGWVAMAPKPGPYVKDMMDAAMFYTNRVLKEYKDVDKKHADWVRAYLNIWTDMQAYIKEHHTTGLTWKKTGPKASGAAPAPAAPPAPKACPPPPPPGGPPPPPPPAPASAPADDSVSRSQLFAQLNQGENITKGLKHVSDNMKTHKNPSLKTQGGPVRSGPKPFTSPKPTGVGAPAAKPVVKKQPPVLELEGKKWKVENQENVSNLEISDTELKQVVYIYKCVNSTLQVKGKINSITVDNCKKLGLVFEDAVGIVEIINSKDVKVQVMGKVPTISINKTDGCHVYLSQDSLACEIISATSSEMNILVPTSGGDFSEFPVPEQFKTVWNGQKMVTTVTEIAG
The following text describes a protein:
Function:
Component of the caffeine dehydrogenase complex that catalyzes the hydrolytical oxidation of 1,3,7-trimethylxanthine (caffeine) by incorporation of an oxygen atom originating from a water molecule into position C-8 to produce 1,3,7-trimethyluric acid (TMU). Coenzyme Q0 (ubiquinone-0) is the preferred electron acceptor and, to a lesser extent, coenzyme Q2 (ubiquinone-2) can also be used, but oxygen and NAD(P)(+) cannot. Is involved in a caffeine degradation pathway that allows Pseudomonas sp. strain CBB1 to grow on caffeine as the sole carbon and nitrogen source. Is also active with theobromine as substrate, but shows a very poor activity with theophylline and is not active with xanthine, 3-methylxanthine, 7-methylxanthine, TMU, and 3,7-dimethylurate.
Sequence:
MFADINKGDAFGTWVGKSVPRREDADILAGRAEYIADIKLPGMLEAAFLRSPFAHARIVSIDVSQALALPGVYDVMVGADIPDYVKPLPLMITYQNHRETPTSPLARDIVRYAGEPVAVVAAINRYVAEDALELIVVKYEELPVVASIDASLAVDGPRLYEGWPDNVVAKVSSEIGDVDAAMASADLVFEERFEIQRCHPAPLETRGFIAQWDFKGENLNVWNGTQIINQCRDFMSEVLDIPASKIRIRSPRLGGGFGAKFHFYVEEPAIVLLAKRVKAPVRWIEDRLEAFSATVHAREQVIDVKLCAMNDGRITGIVADIKGDLGASHHTMSMGPVWLTSVMMTGVYLIPNARSVAKAIVTNKPPSGSYRGWGQPQANFAVERMVDLLAHKLQLDPAAVRRINYVPEARMPYTGLAHTFDSGRYEVLHDRALKTFGYEAWLERQAAAQAQGRRIGIGMSFYAEVSAHGPSRFLNYVGGRQGGYDIARIRMDTTGDVYVYTGLCDMGQGVTNSLAQIAADALGLNPDDVTVMTGDTALNPYTGWGTGASRSITIGGPAVMRAATRLREKILSIARHWLQADPDTLVLANRGVMVRDDPGRYVSFASIGRAAYCQIIELPEDVEPGLEAVGVFDTVQLAWPYGMNLVAVEVDEDTGAVSFLDCMLVHDMGTIVNPMIVDGQLHGGIAQGIAQALYEELRYDENGQLGTGSFADFLMPTASEIPNMRFDHMVTESPLIPGGMKGVGEGGTIGTPAAVVNAIENALRPITNSKLNRTPVTPDRILTAISAGACA
The following text describes a protein:
Function:
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases (By similarity). The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. The MRN complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11, to initiate end resection, which is required for single-strand invasion and recombination. Within the MRN complex, NBS1 acts as a protein-protein adapter, which specifically recognizes and binds phosphorylated proteins, promoting their recruitment to DNA damage sites. Recruits MRE11 and RAD50 components of the MRN complex to DSBs in response to DNA damage (By similarity).
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to DNA double-strand breaks (DSBs).
Domain:
The FHA and BRCT domains are likely to have a crucial role for both binding to histone H2AFX and for relocalization of MRE11/RAD50 complex to the vicinity of DNA damage.
Sequence:
MVWALTPVDTVRGAQRCYIFAAGTYKVGRKDCDVIVQTDTSISRVHAEIVVEKMVAWDPQSGAPANPSYVRVVDRSKYGTFFNKVQGTQGSRLHKDEDAMLADGDTVTFGTGNATFRLSFVPIVVFFHGKKSGRISPCLQAVMTSIGAYATRKWSDECTHVLVDESCSLTPELLDAVLAKKQIVLGDWFKVMAEKNIHTEMPSSTQYIPKLTLDGMEIQVVEIKLIESCLAGYTFILGSSEKYKFGDKLHALLESTGAKYLHVDEFCANSQDSGAGENDKDILLVPAKSPLEFSKIRGLFPLSKITDVKLFAAILSGHLEATAIEPPAYIVASSNSTDETIVVDSDVEIDTATSDHTVAASKSEHHIEHISDDKKEVVAISEEDAVNLVEAKTSINLHSDQEKDEIVKPMEEDVKVIEKTATMRGFKVEGEDIPVMTKVPKDETLDSRDETCHVIYTQNLVVKSILQSARAESIETGGINFKRFRKRGAVSGNSFKDLIPYSREPYRESDYERGTVTDFMREEKKRRQMEAIAEDLFNNAKPKKKAAAGSSIHTMLTGRR
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MEKYSGILLLLLPILMSFVAVSLNSGYANAAVFLPPEDKPLVRHYYKKLNTCANVEPFVQHQVKLYWDKDKTITAKLLKLLYADCMVNGCDASVLLTGPNTERNSSKNARLDGYLLIDKIKKVLEIRCPRTVSCADILNLAVRDAVHYAGAPSYPVFLGRRDGVESKAEWIDYPSPSMSWEEGLAYFESKNLDVQDFVTLLGAHTMGQAHCSSFYDRLYDFQGTGKPDPSMKRSVLVKLRDQCPKNSKNDSPVYFNEEYGSNYTFTNKLYTKVLAHESLLRVDQQLSYGSDTGELVDEYAKSLELFRRGFALSISRMGGLKVLTGKNGEIRQDCKFTNKNNPNIN
The following text describes a protein:
Function:
May be involved in the turnover of nuclear polyadenylated (pA+) RNA.
Sequence:
MSKEKDRLLIQQRHALLWWAFSPDFSSTVVLVFPVCLLHMCLLLAFSPWSILRTCQKLEMIIENPEALKSWLTAVLAPLCDADPAALAKYVLALAKKEKPESELRGAMCDQLDVFLQQETKGFVDKLFVTLETKSYLQSNPEPPSAKVESTTTTTTATEQASTGVTNGQNLVIPPVVTVPVQPLPVPVLSAPSTDSRAKKSSSDRTKRRSWSPRSRSRSRSRDRDRDRPVRRSRSRDRSTRDHRGGRSTWDDRRGQSRRSPVSNRRSDRRRSRSPMPPRRLSRSPRGSRRARSPIPPPPVVAPLDNVVGAPGLGLLAVGATAADPAIVVGVTVPSAAIQSVVVAPSSAAQQQHERGPKFRCRDYDEKGYCMRGDLCPYDHGADPVVLEDVELSSMLSTNYNRPPPPVVGTTGAAGAPPGPLPVGPPPHLRGPPPSLPPSGEPYNPDAPGISWPPPPLVGLRPLGPPPPFGHPPSHRLPPPHMRIRGPLPPRGPPPMGLLGSAPPPRELINVPTAEEGSDSGLKRSVRDAGLDSDGHLAKKGHFDYNRLGNPPAQLQQQQQQQQQVTGQSNHGQPPQRRFDPTNCCLEVKKIPRGLNNISVLNNHFSKFGKIVNLQVSYNGDSEGALVTFSSHNEAQAAYRSTEAVLNNRFIKVFWHNKEVSSPEMKGKQENVPPSSKVPIRERLGGAHPQRVLAQSQAPAPIVDEAALKEASEAKEKEREKAVAAIKRSQEILAAKEALKKKQEEQKREATKLQVDLHRRKQELLDKQLQQQRVLIERLEKNKSTIKTDERAAVMQTVRNLQETIEKLKKDLQTTSPNQGATAVANAPNVGVPTHPAKTPEEAKKEILDVEIELYQKQMEGSDTTELQRRVQELNSIISQSHRGHPSNRRGARISSRGTLRGRGRGLSARLSARGRGRGGYYVGPHVSVDRRPTQIKATGFENHQQGDILAHFANFGEVVDYHVDEDYPALTIRYKSRKDAEMALAQGRSFTGASLSVSWHMPPGSVPKVKDHVAAEEEDEHSAGRIEGSASAEEDEEDENEGLDDLLNYEEDDEDEERSWRR
The following text describes a protein:
Function:
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
Sequence:
MAVYAEKVEGARAATSTRPSAGAVYRNIYAKDGITGVPEGIESPWDLFSKSVQKNPTNNLLGCRKTIDGKAGPYEWLSYKEVYDSALQIGSAIRKCGVNPGAQCGIYGSNCPNWIIAMQGCNGQAISYVPLYDSLGPNAVEFIINHAEVSLVFVQEKKIPAILACLSKCNYLKTIVSFENISSTQRKEVEEAGVSCFSWDEFSQLGTMDCELPSKQKTDVCTIMYTSGTTGEPKGVILTNAAFTSEVHSVEYLFSKTDKSATPEDVYFSFLPLAHIFDQIVETYCIAKGTSIGFWQGDVRYLIEDLQELKPTMFCGVPRVYERLYTGVVDKISSSGSLRKSLFDYAYNYKLRNLEKGLRQDEAAPLLDKLIFSKIKQSFGGRVRIMISGGAPLPHHVEEFLRVTCCCVVVQGYGLTESCGGCFTSIANVYPMIGTVGIPSTAIEARLESVPEMEYDALSSTPRGEICLRGNILFSGYHKRQDLTEEVLIDGWFHTGDIGEWQTDGSLKVIDRKKNIFKLSQGEYVAVENLESIYSRCNLIASIWVYGNSFESFLVAVVVPERKALEDWAANNNETGDFETLCKSAKAKKYFLEELNSTGQKYKLRGFEMLKAVFLEPIPFDLERDLMTPTFKLKRPQLLKYYKEIVNKMYSEAKGPKA
The following text describes a protein:
Function:
Transmembrane glycoprotein that functions as both a receptor and an adhesion molecule playing a crucial role in cell adhesion, motility, migration and invasion. Extracellular domain enables binding to extracellular matrix proteins, such as laminin, integrin and other ligands while its intracellular domain interacts with cytoskeletal proteins like hemoglobin, facilitating cell signal transduction. Serves as a receptor for laminin alpha-5/LAMA5 to promote cell adhesion. Mechanistically, JAK2 induces BCAM phosphorylation and activates its adhesion to laminin by stimulating a Rap1/AKT signaling pathway in the absence of EPOR.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MEPPDAPARTRGAPRLLLLAVLLAAHPDAQAEVRLSVPPLVEVMRGKSVILNCTPTGAHDHYVLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPPYQLDSQGSLVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCNSRNGNPVPKITWYRNGQRLEVPVEMNPKGYMTSRTVREASGLLSLTSTLYLRLRKDDRDASFHCAAHYSLPKGRHGRLDSPTFHLTLHYPTEHVQFWLGSPSTPAGWVREGDTVQLLCRGDGSPSPEYTLFRLQDEQEEVLNANFEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNGTYICEASLPTVPVLSRTQNFTLLVQGLPELRAAEIEPKADGSWREGDEVTLICSTRGHPEPKLSWSQLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTVSPQTSQAGVAVMAVAVSVGLLLLVVAVFYCMRRKGGPGCRRRREKGAPPPGEPELSHSGSERPEQTGLLMGGASGGARGGSGGFRDEC
The following text describes a protein:
Function:
Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes.
Sequence:
MRRDVNPIHATLLQTRLEEIAQGFGAVSQPLGAAMSHGALSSGRRFRGMLMLLAAEASGGVCDTIVDAACAVEMVHAASLIFDDLPCMDDAGLRRGRPATHVAHGESRAVLGGIALITEAMALLAGARGASGTVRAQLVRILSRSLGPQGLCAGQDLDLHAAKNGAGVEQEQDLKTGVLFIAGLEMLAVIKEFDAEEQTQMIDFGRQLGRVFQSYDDLLDVVGDQAALGKDTGRDAAAPGPRRGLLAVSDLQNVSRHYEASRAQLDAMLRSKRLQAPEIAALLERVLPYAARA
The following text describes a protein:
Function:
Molecular adapter that stimulates membrane curvature formation and subsequent endoplasmic reticulum exit site (ERES) establishment by recruiting PI3K complex I, leading to COPII vesicle-mediated transport. Promotes endoplasmic reticulum (ER) exit of cGAMP-activated STING1 oligomers.
Sequence:
MPKVVSRSVVCSDTRDREEYDDGEKPLHVYYCLCGQMVLVLDCQLEKLPMRPRDRSRVIDAAKHAHKFCNTEDEETTYLRRPEGIERQYRKKCAKCGLPLFYQSQPKNAPVTFIVDGAVVKFGQGFGKTNIYTQKQEPPKKVMMTKRTKDMGKFSSVTVSTIDEEEEEIEAREVADSYAQNAKVIEKQLERKGMSKRRLQELAELEAKKAKMKGTLIDNQFK
The following text describes a protein:
Function:
Putative proton-coupled transporter that delivers pathogen-associated molecular patterns to cytosolic pattern recognition receptors as part of the innate immune response to microbes. Likely transports anhydro-muropeptides that contain the amino acid diaminopimelic acid (DAP-type peptidoglycan muropeptides) such as tracheal toxin (TCT), common in Gram-negative bacteria. May transport TCT across the phagosome membrane for cytosolic recognition by PGRP-LE, triggering the activation of imd/Relish pathway and production of antimicrobial peptides. The transport mechanism, its electrogenicity and stoichiometry remain to be elucidated (Probable).
Subcellular Localization:
Cytoplasmic vesicle, phagosome membrane; Multi-pass membrane protein.
Sequence:
MNEEPHAHENLVAKAQRSGDADPEVASTASEKQRSSGASAIAVGTEFPGNPQASRPQSLGMYLLEPFILILLFAYNFSSTVLKNEVIYQSCTAGFGYPDSVCQLLGTKNITNETKRIEEQVQPYAAQVTLAMRLVECFIPAFCGLFAGSWADHYGRKPLLMCSFLGYGLQYLISAAIAYCAMYTQGLVSPWWYVLSIVPLSCLGSSVTYSVAAVCFIADVSGGKVRSYRMIAYELAIYVGLLLGSLGSGYAYEATDAYIVFSISAVCIFTALFLMALLLPESLPARNRTLSTPTTDTSVVSMLKSLWSTCSKPREHQNRFMLTTIMVVLLLTAFVSDGSNSVFYKFMRIKFHWTVKQFTEYETVGILVPAVAGSGGVLFIWSLRKCTNSAILWLALVSLLSHCSSSLMKGFALESWQIYVAIGLGVFKSLVNPMCRTMITNLLPADERGKIFALLGVLQALSPLISSTLYVAIYTRTLNTEPGIFNVFSAFLFGIGIILLGTVWHKKSRNLVYYEPVFK
The following text describes a protein:
Function:
Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MPLASPRQLFLLAFLACVAIMGGALYLEHVVGLEACPLCVVQRIFFILIGLTCLAGAIQGPGLRGRRIYSVLVFLLALGGGATAARQVWLQTVPLDQLPACLPSLDYMMQALPFQEVIRLVLHGTADCAQVSWTLFTLSIPEWSLLAFVAYLGFSIVQFLRRA
The following text describes a protein:
Function:
May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities.
Subcellular Localization:
Cytoplasm.
Sequence:
MIKLLCCCESVMCKSVICVFSSRAFTYLLVIWVLAISAQGSVGPSTSTSFCTESKECLEYELICKTDEYEVSVNRHTHMHTHNVAFYMCAFVSRFDTTAPPAGFQLTPRPISWEWVQPWLSGDSSSTSPGQMKEVRDWSEHLSAASCLHHIWTFWTGVQMEMTAPVLVKIPEDSKMWGPAIYTLNFLLPAAYQENPPAPTNDKLYFTEMPHMDVYVRTYGGWMLSIDSRSHTYLLTAELERVRATYNHSYHYGVGYDSPLKLLNRHNEVWYVAEGQPVCADPQEPSPAHTTRPTPTHLPSASPSDLLLRMLSDSPSMSSSNVSSNATFNTSSLLPSDTSPLLPSEAPSSRPSDQTLDSSQPTPSAQMPLNPATNSSDPVSESPLSELQPDAELWNSTAHNPMDSEDEQNTVSEPVDAV
The following text describes a protein:
Function:
Participates in sulfur mobilization (SUF) pathway for iron-sulfur (Fe-S) cluster biogenesis. Enhances cysteine desulfurase activity of SufS. Probably functions as a sulfur acceptor for SufS (By similarity).
Subcellular Localization:
Plastid, apicoplast.
Sequence:
MNKKKLKAHFFVLYIICSCFILILSIKHDKYNNESKKKKKFFKIRTKIIFYKLKKVNQIKNAPQLYIQFYKPKCHKTTQSLKDIFNELSGNKNPENPKNIDEYNLTPKLKKTVELFQSMPNSPYYKSQQVILMGKKISSMPDKHKIRQNQVLGCQSVVYIYPKVEENEDKKKVIVWLGHSDGLLTKGIVYILTDGLSGYMPEDILKVNPNFITLTGISEFLTMSRINGYLNIMNKIKIFCTNILKNMDN