lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MQHASQSILALDEQSYELLTQKPRNYTLFVVLTSTVPQHNCKPCVEWHTRYKIVADTWAKSFESGKLYFSELDFVHGQSVFSKLGIQSVPLVLRFPPTDGPQAIKGIYELYDLNRNGFSVEPFISHIEAVTGVKIKITKPLDYGKLAITIVIGATAAIVIFTFYTQIIAIITLKALWISLTLTTTLVMCGGYMWNTIRTPPFIGENDGNLHFLSGGMQYQFGVETHIVAIMYGIASAAFIALVVYVPKMENKSAQRTTVFLCLLAFMFIYSLILAVFKLKAGQYPFRLMF
The following text describes a protein:
Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence:
MDPQDCTCAAGDSCSCAGSCKCKNCRCRSCRKSCCSCCPAGCNNCAKGCVCKEPASSKCSCCH
The following text describes a protein:
Function:
Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.
Subcellular Localization:
Secreted.
Sequence:
MRSLALAAAALLALSLASPPTVAQQQAAFKLPNEQQAITFASTSSIHPTNFSGEKVVRFTTTCQTQHRELLEQAHRLDLDVWGAKLGNACAVENAEFGCVDIRMASRTHDEDPFRITTSVESIMESLMQPFPERLKSTTLIEDLGQLVAQQQDLALTPSKDQEWFEGYHTLEEIEAYMNMLQQSYPAHVKVTEIGKTHEGRSILALKIGDGLDSEPPSPPEEPQPEPQPQPQPQPQPQPQPQPDPPINMTWTEEKLGVMITGGQHAREWISTSTSLFFAADLLHAALGNRTQPNATFSAEWDAFRRKSRKGRNKTRQTWTRSSALSVLRTFTISVIPVTNPDGYVYSWTHNRMWRKNRQPNKFPSGLFCKGVDLNRNWAYGFATDAVRTLAGPCSEMYAGTTAFSALETSALATYMSDAANNVRAYFDLHSYGQLLMYPFSHSCNEPVGDEEDLLELSLGAVSALKRVHGRQFNAGKVCAVYAQGGGNSIDWSYASTQGASGDDKKPIKWSFSIELRDGGTYGFLLPPKQIVPAADELSAALSYMFDFIAKKESHSQS
The following text describes a protein:
Function:
Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface (By similarity).
Miscellaneous:
MISCELLANEOUS: Increases PLD1 and PLD2 levels, possibly by stabilizing the protein.
Subcellular Localization:
Cytoplasm. Note=Associated with microtubules.
Sequence:
MAEYGTLLQDLTNNITLEDLEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNLSYIEHIFEISRRPDLLTMVVDYRTRVLKISEEEELDTKLTRIPSAKKYKDIIRQPSEEEIIKLAPPPKKA
The following text describes a protein:
Function:
May have a role related to the spindle integrity function of the DAM1 complex, which is essential for proper chromosome segregation. Causes growth arrest when highly overexpressed.
Miscellaneous:
MISCELLANEOUS: Present with 264 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Bud neck.
Sequence:
MNDKLQEEHNEKDTTSQINGFTPPHMSIDFHSNNNSNIIETIGVSKRLGNSVLSELDSRASSKFEFLKDQSEQQYNGDKNNEPKSGSYNINEFFQAKHDSQFGQMESLDTHYTLLHTPKRKSQHAIPQDRSDSMKRSRPSRSIPYTTPVVNDITRRIRRLKLRNSLVNGNDIVARARSMQANSNINSIKNTPLSKPKPFMHKPNFLMPTTNSLNKINSAHRNTSSSSTASSIPRSKVHRSISIRDLHAKTKPVERTPVAQGTNSQLKNSVSVFDRLYKQTTFSRSTSMNNLSSGTSAKSKEHTNVKTRLVKSKTSGSLSSNLKQSTATGTKSDRPIWR
The following text describes a protein:
Function:
Probable disease resistance protein.
Domain:
The LRR repeats probably act as specificity determinant of pathogen recognition.
Sequence:
MALTKLRFVNQFSQWLCVRKGYIHSLPENLAALQKAIEVLKTKHDDVKRRVDKEEFLGRRHRLSQVQVEIERLCFCGFCSKSFGKSYHYGKMVSVMLKEVENLSSRGVFDVVTEENLVAQVEEMPIQSTVVGQETMLERVWNTLMKDGFKIMGLYGMGGVGKTTLLTQINKKFSETDGGFDIVMWVVVSKTSEIYRIQEDIAKRLGLTGEEWDKKNENKRAVDIHNVLRRHKFVLLLDDIWEKVNLELVGVPYPSRENGSIVAFTTRSRDVCGRMGVDDPMQVSCLEPEDAWDLFQNKVGENTLKSHPDIPELAKQVAEKCRGLPLALNVIGETMACKSTVQEWRHAIDEEWKKTEVKMHDVVREMALWISSDLGKHKDQCIVRAGVGLHAVPEVKNWRAVRRMSLMKNELEKILGCPTCPQLTTLLLQKNHKLVNISGEFFRFMPNLVVLDLSWNSSLTGLPKKISEVETTNTSEFGVHEEFGEYAGVSKLLSLKTLRLQKSKKALDVNSAKELQLLEHIEVLTIDIFSKVEEESFKILTFPSMCNIRRIGIWKCGMKEIKVEMRTSSCFSSLSKVVIGQCDGLKELTWLLFAPNLTYLDARFAEQLEDIISEEKAASVTDENASIIIPFQKLECLSLSDLPKLKSIYWSPLSFPRLSELAVQEHCPKLKKLPLNSKSGTAGVELVVKYGENKWLEGVEWEDKATELRFLATCKSLYR
The following text describes a protein:
Function:
Secreted effector that acts as an elicitor of hypersensitive response (HR) specifically on plants carrying defense protein R1, through its interaction with this protein. Also acts as a virulence factor that promotes colonization and suppresses cell death induced by CRN2 as well as callose deposition, a hallmark of basal defense. Interacts with host exocyst component Sec5 and thereby disturbs vesicle trafficking, a cellular process that is important for basal defense. By targeting and stabilizing Sec5 in the cytoplasm, the exocyst complex is thus out of balance and not able to mediate the focal secretion of PR-1 and callose.
Subcellular Localization:
Secreted. Host cytoplasm. Host nucleus. Host peroxisome. Note=Nuclear-localized Avr1 triggers the R1-mediated HR, whereas cytoplasmic localization is required for suppression of CRN2-induced cell death. Also localized at Sec5-associated subcellular bodies.
Domain:
The RxLR-dEER motif acts to carry the protein into the host cell cytoplasm through binding to cell surface phosphatidylinositol-3-phosphate; The C-terminal domain of Avr1 comprises three motifs (W1, W2, and Y), two linker regions (ln1 and ln2), and at the very end the T-region. The T-region of AVR1 is important but not sufficient to trigger R1-mediated HR and W1, W2 and Y are equally important for recognition by R1.
Sequence:
MGLMHRVLLLATFALLCMHAKAAGFDHDKVPRTVERGGGARQLRTATMSDDEARVSKLPSFIESFVKNRKIESWIQNKVTDDFVLSELKLVRLPGTSLADDPNFKLFQKFKIGGWLEEKATTTKAWENLGLDSLPFDQVSKIDEFKTYTQYVTVLNKKASKLDIDQWHGLLSGGSPEELMAKAMILRTLGRDVLERRVMLGGHVVVPF
The following text describes a protein:
Function:
Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSQGPPPVESSEPEAKVLHTKRLYRAVVEAVHRLDLILCNKTAYQEVFKPENVSLRNKLRELCVKLMFLHPVDYGRKAEELLWRKVYYEVIQLIKTNKKHIHSRSTLECAYRTHLVAGIGFYQHLLLYIQSHYQLELQCCIDWTHVTDPLIGCKKPVSASGKEMDWAQMACHRCLVYLGDLSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLAGSKYYSVEAMYCYLRCIQSEVSFEGAYGNLKRLYDKAAKMYHQLKKSETRKLSPSKKRSVDSELTSLCQSVLEDFNLCLFYLPSSPSLGLTNEDEEECESGYAFLPDLLIFQMAIICLMGVHSLKRAGSKQYSAAIAFTLALFSHLINHVNIRLQAELEEGENPVSAFQSDGTDEPESKEALEKEEPEPEPPTVVPQADEGRKSRKHSRLSCLRRRRRHHPPKAGDDSDLSEGFESDSSHDSAQASDGSDSGSDKSLEGRGTAFDAETDSEMNSQESRSDLEDIEDEEGTRSPAQEPPQTRSEVPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTAEPNSVASHRPCVNGDMEKPLEPASEDGSESEGSESSSRSCRNERSLQEKLQALMAEGLLPAVKVFLDWLRTNPDLIIVCAQSSQSLWNRLSVLLNLLPASGELQDSGLALCSEVQGLLEGCELPDLPASLLLPEDMALRNLPPLRAAHRRFNFDADRPLLSALEESVVRICYIRSFGHFVARLQGSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMLEVSQLEGSLQQPKAQSAMSPYLIPDTQALCYHLPVIRQLATSGRFIIIIPRTVIDGLDLLKKEQPGARDGIRYLEAEFKKGNRYIRCQKEVGKSFERHKLKRQDADAWTLYKILDSCRQLTLAQGAGEEDPSGMVTIITGLHLDNPSALSGPMQAALQAAAHASVDVKNVLDFYRQWKEIG
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.
Sequence:
MSLPQSKVLTSFGTANRTPRAAETHPLTWRLRDDGQPVWLEEYQTKQGYDAVRKALGQMSPDEIVSTVKDAGLKGRGGAGFPTGVKWGLMPKDESMNIRYLLCNADEMEPNTWKDRLLMEQLPHLLIEGMIISAKALKAYRGYIFLRGEYVDAAINLRRAVEEAKAAGLLGKNILGSGFDFELFVHTGAGRYICGEETALINSLEGRRANPRAKPPFPAVSGVWGKPTCVNNVETLCNVPAIIGNGVAWYHTLALPGSEDHGTKLMGFSGKVNNPGVWELPFGITARELFEGYAGGMRSGYRLKAWQPGGAGTGFLLPEHLDAQMYTAGIGKVGTRMGTGLAMAVDDSISMVSLLRNMEEFFARESCGWCTPCRDGLPWSVKLLRSLERGEGQEGDLATLEQLCNFLGPGKTFCAHAPGAVEPLASAIKYFRSEFEAGIKGSGDNRKSIKGIQPNLLGERW
The following text describes a protein:
Function:
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MISSKLLLAIFGFALVFSAVRAEDAADGEVHEEDEIGGASKDAAVSFHFTYPIDANVNKEVFAGKPIKFLIGFKNGGEKDFTVKFAETSFRYHQDYNFHLQNFTAAQFNRKVGPKEEVTLDTSIPVFEQFSGRPLGLVVRLHYEDSDNQYFVHTAFNETITVADDDSNYNTETYFMYLVFAVIAVLLLMASRSYLEKVTRKHGMTKRAPVVEQGTTKTGEVDFEWIPRDVLNNKKSPKPASPKPKKAQNAE
The following text describes a protein:
Function:
Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAVTVVTENIAAQLDLLVDLHRSFRYAAIDTEFPGFIQSTPPYASEEDRYADVKYNVDKMKLIQLGITLFDENGSTPWQGCCWQFNFSDFDPLVHPSSPKSLELLRRSGHDLEGNQRNGINGDKWSNVLRNKLFDRRYDSVYVTFHGLYDVAYVIMLITGGAPLPPTLREFIVSIKSIIMLFVMRKNFNTKIEIK
The following text describes a protein:
Function:
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Sequence:
MVGTTLKMRGDENASENFKQVQLKKLTVPSMEATTKRAALGDLQNRGISRPIAAKDAAQKDSKDLKLTDALRNAKARVDSHWKKQPLGSTNGNGNGAVPPKVNEGGVSAFLRSNSVRNRVPTKTTVEPTKVTVKSSSSENVNEPTLKREDSNLSKKSLTKLRAALAKPVMGVSGIRREPVAVSRKEAETKKELPETKKDSLEVKKDATRMPLIRGNSAVTTTTSTMPTTMSLSSKRLAGIEDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPITRLIAKLARDAPQAKLKAIYNKYQGSKFQKIALRTELTGALMDSIVGQSQRK
The following text describes a protein:
Function:
Has a role in the negative regulation of gluconeogenesis. Required for vacuolar catabolite degradation of fructose-1,6-bisphosphatase (FBPase) (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MFMLKSLGKYIWGNTNSTEIVQIPYGQLYSVHENYRECMFKDASASIRRTTAEFQYQLVIQRAYEEGEEELEDDGDEAEDEQSFLLDEKLHLRFDVNKDSITIMWDNPDFQDGTLYEFTCENCLQEGVAYTFEMVALQCMYERKYRQSHEKATLADLEQFSNPITRPSKEVDSLENIVTKLDLESEDLMRLKKQEQLDDEIAKKYLLGQQEAEEPLVQQQTSIVNPEKEEVTKTENIKSLEGELMGTISAELHLFDAVEEVFILQDPNVEASVFDLGDWNYWFTISTEEKTWLSQSVDADMNPVFSFEHLSFIWNYFDANSNAFSWLLRFDSQVRMEQFQELLMRALWESLNQQRWLKIDDEQRDYVMETFHEDEELEDSEDEEFARQQLLSRKEEEEEEDEEASDFEDSFADFSDGEADDLDESRWRKEAAKEHNSLLAVGYKNDRSYVVRNNKIGVFKHVDEKGLKFQTALNNLSTPKGKSLRPSKLMLHNQDSSILFQTENAPHSLYHMDIEYGKIVDEWKVHDDVPLVTFTPDNKFAQMTAEQTLIGLSNNSIFRIDPRVEGNKLVAEQFKQYATKNDFSSAATTENGYIAVASNKGDIRLFDRIGVNAKTALPALGEAIIGVDVTASGDFVLATCKTYILLIDTRIKEGRYAGRLGFERNFAKDKKPKPKRLQLSPQHIAMMQRELKGGASFTPAKFNTGIDAKETTIVSSIGPFLISWNLDRVKRGFTDSYKIRRYDANVQAEDFRFGTDRSLIVALPDDVAMVDKSSLRRPTRESICTPVKKLRSKHDIVNAPY
The following text describes a protein:
Function:
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MWSSIAAFPVLVPVALACLGYEGGVPTPTAHHSNSAVIEVAAGQVFDAGWAKYDRGSGACKGQSEGDWKDAVFYLHSGATLKNVIIGANQAEGVHCDGPCTLQFVWFEDVCEDAITIKNDKAGQETWIIGGGAYHASDKIVQHNGCGTVNIINFYAEDYGKVPRSCGNCDKQCKRNVYVEGTTARNGGEVVGINLNYGDTATLKNVCADSAHPCVFYDGCAGDCEPKKVGYCSG
The following text describes a protein:
Function:
Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively. Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also functions as the substrate recognition module for the DCX (DDB2-CUL4-X-box) E3 ubiquitin-protein ligase complex DDB2-CUL4-ROC1 (also known as CUL4-DDB-ROC1 and CUL4-DDB-RBX1). The DDB2-CUL4-ROC1 complex may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MKVRSAARLHGTLPGASPSRTAVLRAPPRPQAAPARIALHAATSTPQENFSLAAAAEPPGPPALRREPAQSRPSGEHLAYLTGSRTQPGGQRAPGPSGTGPPLFQPRDAGAPAPPPAVPAGRARRWGQPAGGGAAPKTPSAPPSPDPINGPCSGRCRRDVEALCTPVTALLAATKTRRIFFCTSFLSCNPGLCGARGKQWSDRMAPVNQPKDKKHEKAHEHRSEEAKSAGKRKLDYEGLENEPLAKKLFLRKTSKAQEKIGWNRGGTVMRNTRALFHQPKWQCSIVHYVYQNMLGGSIRAQLRQCLQLPFLRSLTSYRLFRTASPFDRRVTCLEWHPTHPSTVAVGSKGGDIILWDYEVLTKTCFIKGMGAGGAITGMKFNPFNPSQLYTSSVAGSTTLQDFNGNTSRVFTITENWDCWYCSVDVSASCRAVVTGDNLGNVVLLSTSGEEIWKLKLHKKKVTHVEFNSRCEWLLATASVDQTVKIWDLRNIKDKANFLHVLPHDKPVNAAYFSPTDGAKLLSTDQHNEIRVYSCSDWTKPQHLIPHPHRQFQHLTPIKATWHPRYDLIVVGRYPDPKFPGYTVNELRTVDIFDGNTGEMVCQLYDPNASGIISLNKFNPMGDTLASGMGFNILIWSREEMVMKKQEHLLKAMTEQGIGSRSLSRCGGQRQANPGTSKLKAKLLSWEVEEMGTKTKDSKSQGRK
The following text describes a protein:
Function:
Essential for development of both female (megagametogenesis) and male (microgametogenesis) gametophytes by promoting the formation of large vacuoles early in development, maybe via the regulation of vesicular fusion.
Subcellular Localization:
Endomembrane system. Prevacuolar compartment. Endosome, multivesicular body. Note=Localized to multivesicular bodies in gametophytes during mega- and microgametogenesis.
Sequence:
MASRPSVRHPSHNHPLRGHKAQVEDEIICSGCDLDLLGAYFKCTKSECDYFLHKSCFDLPREIRHKSHPDHPLILLYSPQNNNSTYTCDACGEYGSGFTYNCSICQYDVHVGCVSVPETMKHDEHVHPLALIYKAPCPKDHIFTCDVCDETMPHNLWLYYCQKCDYGAHLHSCVAEEEEKSKKGGRGRGGEGGSGGNGVNRGRSSANSELAAMLKAQREMEQMQIALHLEMQRAKIDKKSRKHMLKMI
The following text describes a protein:
Function:
Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
Subcellular Localization:
Secreted.
Sequence:
MKLLSLATALLATLTTAHPVFDDLITPSTPLDHKRAPAASLRHISNFGSNPSNAKMYIYVPDNLAASPPIIVAIHYCTGTAQAYYTNSPYARLADQKGFIVIYPESPYSGTCWDVSSHATLTHNGGGNSNSIANMVEYTLKTYNGDATKVFVTGSSSGAMMTNVMAATYPALFAAGIVYSGVPAGCFYSQAGGTNAWNSSCANGQVHGTPQVWAKVVRDMYPGYDGARPKMEIYHGSADTTLNANNYNETIKQWAGVFGFDYQKPDTTQDNVPQGGYTTYTWGEGKLVGVYARGVGHSVPIRGSDDMKFFGL
The following text describes a protein:
Function:
Peptidoglycan polymerase that is essential for cell wall elongation.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MALDKRIWMHFDLLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFILFWIVFFIPFRKLGRWLFVFYWACVILLALVDFMGYSKLGAQRWLVIPFISITLQPSEPVKIAILLLLAHLIKINPPPFKGYDWGMFLKLSFYICLPAALILKQPDLGTALIVLIMGFGILLIVGLRTRVWLPLFIALLVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSKEACTQTKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYLFESNSDWFLKIVALGISILIFVYSSVNIAMTLGLAPVVGIPLPLFSYGGSSFITFMILFGILENLLAFRYIFGYNSKPSFGNFGFLAQLVRALGS
The following text describes a protein:
Function:
Golgi membrane protein involved in vesicular trafficking.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MALSLGQFINVGGMVKDLKSFNFSVYGRWFGYINIILCIALGIANLFHVSGVIAFGIISIIQGLVILFIEIPFLLKICPLSDNFIEFIKRFETNGWRCLFYLAMAIIQYISIAVMATSLIVVAVGLTISSISYAVAYTKHQEFQNTNIIKNPTDDDFPHEAVVREML
The following text describes a protein:
Function:
Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity; Stimulates growth of stationary phase M.bovis (a slow-growing Mycobacterium), reduces the lag phase of diluted fast-growers M.smegmatis and Micrococcus luteus. Sequential gene disruption indicates RpfB and RpfE are higher than RpfD and RpfC in functional hierarchy.
Sequence:
MHPLPADHGRSRCNRHPISPLSLIGNASATSGDMSSMTRIAKPLIKSAMAAGLVTASMSLSTAVAHAGPSPNWDAVAQCESGGNWAANTGNGKYGGLQFKPATWAAFGGVGNPAAASREQQIAVANRVLAEQGLDAWPTCGAASGLPIALWSKPAQGIKQIINEIIWAGIQASIPR
The following text describes a protein:
Function:
Catalyzes the conversion of L-ornithine to N(5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as ferrichrome.
Sequence:
MSAPTLDVESPLAASTSSLRAMNMVSSHTTVAKDEIYDLLGIGFGPAHLALSISLRESSEANETNFKAHFLEKRGHFAWHPALLLPGSQLQVSPLKDLVTLRDPASTYSFYNYLHSHGRLARYINKEQGVPSRREWTSYLAWAARRMNQAVSYGQDVISIEPLALASASPDAKQDTVAVRPASAQEADSLCLYQVRIRDESTGHIVNRYARNLSVAVGGVPKLPPAFQAAWDEQQRAPHSIPRLVHSGFYIPSMLKLEPELHKAASLRHPDAAAQLDDSSRLRLAVIGAGQSSTEMFMNLHSRFPSAIVTMIFRASALVPSDDTGFVNSAAFDPERTDEFWQASETQRRKWLQEFKRTNYSVVRTDLLNELHDAMYDKYEVQLPEELQDPTEKQAGRMEMRRCTEVVEVTPLDDGIQLTMRDNLRNAKLETIRFDAVFLGTGFIRSPSKMRFLEQLKPFYPALDAEWMSRDTIAEEDEVSKSIDVEDEEVIERRREMLRGITRDYRLVPASAMQSDAVRSGKSSPGSGSDASSTSSQQTLASENSTENLPEASLYVLGGNEATHGLSDSLLSIVAHRAGELTTSLLQRLPRTRRGTASSAATQPAASTVASAAKTSPTVSVTQTKARQAAQVVNDKLAALSGLHLDATS
The following text describes a protein:
Function:
Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFLGLRELVYSKLRYILVTGIMVLIMLLSLILSGLANGLAYDNASSVADNGVPYYVLSKDAQDKLSRSQFPESKLADVKKDANVKDAAVLGQSMQTLKRESDDKKFSVALFGIQPDSFLAPKISDGANIQVTKPDEIVVDSSLKSDGIKIGDVLMDDILNRELTVVGFTENQKYSHAPVVYINIATWQEINPVLYHQKIPQTSTIAIKTENPDKGVTLTDKDLTTIDHKEFLNQIPGYSAEQMTLNMMIFFLIIIGGFILTAFFYVMTLQKTTQFGILKALGTKTSYLVKSIITQVVIISIISILISVGVTLILPSIMPAAMPFRLSPMTIALYSGLFFLVALFGALLSLRRIAKVDALDAIRGGDE
The following text describes a protein:
Function:
Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
Sequence:
MRCWGCSSMRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVSRITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEILAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD
The following text describes a protein:
Function:
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKELDTVEVSIRVPFGKSKRLSTTASRRARVQSIMYFLAFNAASKYYTNYELLHNGVEVDEQQLISELAGNEQTVHLQLRLKPYNTGEVIRHFVTFREYIGFVGDSDDDITSLALSNVAKFRELPLTDIAAASGKTEVADDRQKEEFQVSDAEKAVFTKELDSILELRPSAQDVLKGGSALSKPCLRSLIISGYNPVPAFFRTKGHLLYLQAVTLEGETLHITATVSGFYVNKSSAIKFDPTLKTDAAVCLTLYELLTKHSKKFASHLSQLEAALKAHESVNYVKPISVFLHKTWFPSSLPSNSIDFTEYQLEALNFQTERNFNDEFQAVKETSSEDIVARLEKEKLLNRVIHDFNVAASKGSMEIFYGNMVAMNPDAPRQEHIFLKNNIFYSFVSDLDGHYQDKGGDAAAHAASNQDLHIIKTLLQSNMRSVRHLLTAVVEFGGVRILAQSPVPGILDTAGMKFIKNEKGEEEAIQAKNDITVCYGFDEASNKVIADAEFGSSLDDFAKVFHLKKHEVDGVELKVASTSKGVVGFDKRNYILDLADNNPLDVGFALENFDAVTDEKARYPHRQTLLRRELVEKWWFSKVDGTGSEMEAAYEEGKFSYNPDAYKIEGIEDETVVELSDYLRKEVVPTLVKEVAEGSITAPFNGEHLVDIMHKNGINIRYLGRVIELAEQELEAQRALREAHLQQVEADNKEFTEWEANYLKHIESLIKERQVTIQKLLAEGKEVPAELKEELKLDDKEIRKPHEKEGVAVNNDQLSVLLTLAQIEIISRSIKHVFRKHCHELPAVIIPTFIAFALNLLFGYCYNKAPIAEFPTDGSDIDFAFTKLTREQLLSEISEQAVLRFRYTLPDGWESRYEHTPFALLRPICNKFGIQLLNKEYFFTREQYQNWRQAQDKKIRSKLVEPVSTFSINDLSVRPIIKVATLTTGVSDDCWAQGAYMINEEEKQATALALFSQSIAFREETSGYVHPTVAESYLALSTIHSKLEKKSEAVALCRKACAIYERVCGFDSFEMIRSLNNLAMLEMANDSPYNAALCLKTIMSILSVVIPVNHPATINSYSMLHSMCSSLQNSSAMIKVLNKLGDIIVEIDGHKSLPYAVNESRLANLYASVGEYKRSLACIESCYELFSKELGVNHKTTVECNSWITGVENLIESTSQSKALAASKAAAAAKQGEKKPAQKQQQSAELRDKSIDELMNFINGGSAPAKKSKKKKNAKK
The following text describes a protein:
Function:
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody, Midbody ring. Note=Localizes to the interzone of mitotic spindles (By similarity). Detected at the midbody during later stages of mitotic cytokinesis.
Sequence:
MKSAKAKTVRKPVIKKGSQTNLKDPVGVYCRVRPLSFPDQECCVEVINSTTLQLHTPEGYRLNRNGDYKETQYSFKRVFGTHTTQKELFDVVANPLVDDLIHGKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGSFQAKRYVFKSNDRNSMEIQCEVDALLERQKREALPIPKTPSSKRQADPEFADMINVQEFCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVQFDPIKPKLPQSKTLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTKAEGNRLREAGNINQSLMTLRTCMEVLRENQTYGTNKMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEESLQVMRFAEVTQEVEVARPVDKVICGLTPGRRYRNLPRGGPVGDEPLVPEVILQSFPPLPPCKLLDINDEETLPKLADTLEKRHHLRQLMTEDLNKKCLAFKALLKEFDNSLSNKENYVQEKLNEREKVISGQKLEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELESQNQKLQRQFSDKRRLEARLQGMVTETSMKWQKECERRVAATQLEMQNKLWVKDEKLKQLKAIVTEPKPEKPERPSRERDREKIIPRSVSPSPLPLSSNNIAQISNGQQLMSQPQLHRRSNSCSSISVASCISEWEQKLSPFSTPVNVTSLARHRQQEPGQSKTCIVSDRRRGMCWTEGREMVPTFSSEIGVEEDHCRRNTPIPVRHRRSRSAGSRWVDHKPASNVQTETVMQPHVPHAITVSVANEKALAKCEKYMLTHQELASDGEIQTKVIKGDVYKTRGGGQSVQFTDIETLKQELPTGSRKRRSSTLAPAQPDGTESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP
The following text describes a protein:
Function:
Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.
Subcellular Localization:
Cell membrane.
Sequence:
MRSSAARGRKMPNSLPRALPMTLRMYQRLASGLVPLAPALIKRRLKQGKEDPARVGERRGLSRDVRPHGPLVWIHGASVGEVLAAAALIGRLRDLNLRILLTSGTVTSAAVVAKRFPPDVIHQYVPYDSPRYVARFLDHWKPSLALFIESDLWPNLILAGATRRVPMVLINGRMSPRSFPRWRRMYGTISALLSRFDICLAQSKLDAERFSALGGRDVLTTGNLKLDVPAPPADPAKLERLMAMTRGRPIIVAASTHPGEDEMLVAAHRSLVGFFPQLLTVIVPRHPDRGSSIAGLITASGLKPALRSREELPTAATDVYVADTMGELGLFYRLSPIVFMGGSLIRHGGQNPIEAIKLGAAIVHGPHVFNFADVYEALDASGGARQADTQEILVKQLGQLLADPAVRDKIQQAGSSVVEQLGGALERTMTALEPYLLQLRIEMGAANA
The following text describes a protein:
Function:
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG133, thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
Subcellular Localization:
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.
Sequence:
MNQYNVKYLAKILCLKTEIARDPYAVINRNVLLRYTTDIEYNDLVTLITVRHKIDSMKTVFQVFNESSINYTPVDDDYGEPIIITSYLQKGHNKFPVNFLYIDVVISDLFPSFVRLDTTETNIVNSVLQTGDGKKTLRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMVTGVEIADRSVISVAD
The following text describes a protein:
Function:
Catalyzes the addition of a phosphorylinositol group onto ceramide to form inositol phosphorylceramide, an essential step in sphingolipid biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein.
Sequence:
MASSILRSKIIQKPYQLFHYYFLSEKAPGSTVSDLNFDTNIQTSLRKLKHHHWTVGEIFHYGFLVSILFFVFVVFPASFFIKLPIILAFATCFLIPLTSQFFLPALPVFTWLALYFTCAKIPQEWKPAITVKVLPAMETILYGDNLSNVLATITTGVLDILAWLPYGIIHFSFPFVLAAIIFLFGPPTALRSFGFAFGYMNLLGVLIQMAFPAAPPWYKNLHGLEPANYSMHGSPGGLGRIDKLLGVDMYTTGFSNSSIIFGAFPSLHSGCCIMEVLFLCWLFPRFKFVWVTYASWLWWSTMYLTHHYFVDLIGGAMLSLTVFEFTKYKYLPKNKEGLFCRWSYTEIEKIDIQEIDPLSYNYIPINSNDNESRLYTRVYQESQVSPPSRAETPEAFEMSNFSRSRQSSKTQVPLSNLTNNDQVPGINEEDEEEEGDEISSSTPSVFEDEPQGSTYAASSATSVDDLDSKRN