lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity). The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity). PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10 (By similarity). When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation (By similarity).
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Domain:
The three subunits of the retrotranslocation channel (PEX2, PEX10 and PEX12) coassemble in the membrane into a channel with an open 10 Angstrom pore. The RING-type zinc-fingers that catalyze PEX5 receptor ubiquitination are positioned above the pore on the cytosolic side of the complex; The RING-type zinc-finger is degenerated and only coordinates one zinc ions, preventing E3 ubiquitin-protein ligase activity.
Sequence:
MAEYGAHITTASVADDQPSIFEVVAQDSLMTAVRPALQHVVKVLAESNPAHYGFLWRWFDEIFTLLDFLLQQHYLSRTSASFSEHFYGLKRIVAGSSPHLQRPASAGLPKEHLWKSAMFLVLLPYLKVKLEKLASSLREEDEYSIHPPSSRWKRFYRAFLAAYPFVNMAWEGWFLTQQLRYILGKAEHHSPLLKLAGVRLARLTAQDMQAIKQRLVEASAMQEPVRSVGEKIKSALKKAVGGVALSLSTGLSVGVFFLQFLDWWYSSENQEAIKSLTALPTPPPPVHLDYNSDSPLLPKMKTVCPLCRKTRVNDTVLATSGYVFCYRCVFNYVRSHQACPITGYPTEVQHLIKLYSPEN
The following text describes a protein:
Function:
A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Acts as an omega and omega-1 hydroxylase for arachidonic acid and possibly for other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. May down-regulate the biological activities of N-arachidonoyl-serotonin, an endocannabinoid that has anti-nociceptive effects through inhibition of fatty acid amide hydrolase FAAH, TRPV1 receptor and T-type calcium channels. Catalyzes C-2 oxidation of the indole ring of N-arachidonoyl-serotonin forming a less active product 2-oxo-N-arachidonoyl-serotonin.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MDTEANGVGLEWSNTGAVLMLVCTLIFYYWHQRPIHFPPGPRGFPLIGVLPYLGKYPERTMQIWSRKYGPVMSVRVGSEDWVVMGSQESIYQSFVKGGNVFSGRPFVKVANEVTESKGLAMIDFNPTWKTQRKFGNVTLRGFGVGKKSLEERIIEEVEAVKMNILSKEGKPFDITDILSNAIMNVICNITAGQRFEYDDQFFIQIRRHLWFMDPDRTAAFSAMVFVPLLCHIPPYRKKYEQIKQDTKEMMGLFQQLVDQQRKTFDKNNLRDFIDAFILENENGTDESFTDRQLVHYVRELFKAGTETSTGTLRWAMLCLIHYPGAQEKIRKEIFDVLGNSTFPSMSDRNAMPYTSAFIQEVFRFRTLAPLGVPHKTTDTVNFANYIIPKGTTILSNLWAVHNDPTVWNNPRQFKPERHIDDKGKYIQSNHVIPFSVGPRHCLGEQLARMEIFIFLVSMVQKFEFLPDPNKTDLPELDDGVNGVAFVPYPFKLVAKEI
The following text describes a protein:
Function:
Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MLRSLLLLAPLVGAAVIGARDHSQECPGYKATNIREGRDSLTADLTLAGKPCNTYGTDLKNLKLLVEYQTDKRLHVKIYDADEEVYQVPESVLPRVDGKGGSSKKSALKFDYQANPFSFKVKRGGEVLFDTSGSNLIFQSQYLSLRTWLPEDPNLYGLGEHTDSLRLETTNYTRTLWNRDAYAIPEKTNLYGTHPVYYDHRGQHGTHGVFLLNSNGMDIKIDKTKDGKQYLEYNTLGGVFDFYFFTGATPKDASIEYAKVVGLPAMQSYWTFGFHQCRYGYRDVFEVAEVVYNYSQAKIPLETMWTDIDYMDRRRVFTLDPERFPLEKMRELVSYLHNHNQHYIVMVDPAVSVSDNVGYNDGMEQGIFLQTQNGSLYKGAVWPGVTAYPDWFHPDIQKYWNDQFAKFFDPKTGVDIDGLWIDMNEAANFCPYPCSDPEGYARDNDLPPAAPPVRPSNPRPLPGFPGDFQPSSSSKRSTKGSKVGLPNRDLINPPYMIRNEAGSLSNKTINTDIIHAGEGYAEYDTHNLYGTMMSSASRNAMQHRRPGVRPLVITRSTYAGAGAHVGHWLGDNISEWSKYRISISQMLAFASMFQVPMIGSDVCGFGGNTTEELCARWARLGAFYTFFRNHNEITGIPQEFYRWPTVAESARKAIDIRYRLLDYIYTAFHRQTQTGEPFLQPMFYLYPKDKNTFSNQLQFFYGDAILVSPVTDGSQTSVDAYFPDDIFYDWHTGAALRGRGANVTLSNIDVTEIPIHIRGGSIIPVRSESAMTTTELRKKGFELIIAPGLDGTASGSLYLDDGDSIEPRATLELEFTYRKGHLQVKGKFGFRTEVKINAVTLLGQSAPASKSADVASLDSGRQAVTIKTSLDLTGPSEIDLS
The following text describes a protein:
Function:
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MALEETRSKIPAAAQVQHHSQLEEEETLPISDQISTENTSLESSQSKPLSYPHSRSHSLSLSFPLSDTNPHPHSHPHSPQPSKSHFPIQNLPRTSTSEASARSEEELLDPDAAAALADLHPTDTIMDSQPSGHRRRRSSMMNSLDPNSRVPKAKRSPKTSIIGGDTKSGDRGSDDDSRSTSDDMELNNFSEDGDLQDDEETGLTAKSRAKRKKKKIRHQSMDHRIAGDIKVTTDEKKEADWNVVRKSLMNGSLIGLWYIFSLSISIYNKWMFDPKHLNFHFPLFTTCMHMLVQFSLASLVLYFLPQFRPRYDSISNPHNTHVSDSDMAQHEIDMKKPLMTRMFYFTRIGPCGMATGLDIGLGNMSLKFITLTFYTMCKSSSLAFVLLFAFVFRLETPSWRLVGIIFTMTVGVVMMVFGEVDFSTKGFILVIFAAFFSGFRWGLTQILLLRNPATSNPFSSIFYLAPIMFASLLIIATPVEGFPALWEGLKTLVEVKGPIFGPALLLFPGCIAFFMTASEFALLQRTSVVTLSIAGIFKEVVTISAAGLVFHDPLTLINISGLFVTIGAIAAYNWIKIRKMREDAQTEAHRIHEAAERARESGSDADGEDGESDWDGQEGSYVTNDGDILPNPDRFQVKKGESSRAEIAPLVGNSAKKDLSD
The following text describes a protein:
Function:
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
Sequence:
MSFFTQLCSMDKKYWISLAVLSVTVLISALLKKRATETEDIVVVHYDGEKLNFVLRQPRLNMVSYTSFLRRVCNAFSVMPDKASLKLNGVTLKDGSLSDQNVQNGSELELELPKLSPAMQQIEAYIDELQQDLVPKIEAFCQSSPASAQDVQDLHTRLSETLLARMIKLDAVNVEDDPEARLKRKEAIRLSQQYLSKLDSTKNQNK
The following text describes a protein:
Function:
May be nvolved in the import of UDP-sugars.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKLKPNDIYIPLNSIQFKIHHNDINIKYDTEEDNNNNNNNNNNNRYIDDNEKMKISEDESIFKSINNDNKNQQNDNIINSFNRGSNSFLFNIINFYKSPRFLSGGAVLLYVMTTYDFSASNFLLFNQMVVTIVILHILKHFNILKINTNFEKETIKKLMPLSFCYIINVLLGLDSLKQLNIPMYSALKRLVAVVILVMEYFILKKVSPPKIIASVVVMVIGAVVAGITDLSFNSLGYSLVLLSCIFQASYLIYVKKVASNMSTYDMLYYNSVLSLPITIFLMIVNQEIEYFQTFEHLYDSSFQAYFILSIFLGFFLNFCIFFCTSVNSPLTTSVTGQVKNIASTIIGAMVFNDIIIHPINILGLIINIIGSIWYSFLKLTSK
The following text describes a protein:
Function:
Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MEGVGGDGASAAAAFNQRSHELSQTFQYYLDKTVPHAPYRWIGTFVLAFVYALRVYYLQGFYIVTYGLGIYILNLLIGFLSPLVDPELEPSDGPLLPTKGSDEFKPFIRRLPEFKFWYAITKAFCIAFMMTFFSLFDVPVFWPILLCYWIVLFVLTMKRQIMHMIKYKYIPFNLGKQKYSGKRPSASGSSPRAD
The following text describes a protein:
Function:
Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Sequence:
MPPPAHRDRDSKYTAIPMEEAEEILTNLGKQMCHKFEVVDVDLNLLGKVAGENAISTENMPRTRVSTKDGYAVVANDGAKIKAVIGVSLAGSVYNGVLQPGQCVRISTGGVVPEGASAVVMVEHTICTKSNDEGEELEIQIKDHVSDGTNIREPGSETRKGETIVRTGTKIGSAEFGILNAFGIKNIMVYKRPIVTVISTGNEVFTNQNKLQNLKYRFQLVNLDCEEVPVGMIRDSNGPQLVALFKEYGIDAIAGGRVSDDFECIKEKLSQSLKQSDVIVTSGGVSMGEKDNLKEVLLSLGMTIHFGRVMMKPGLPCTVASGQIQIDGALPTLKIVLALPGNPASAWVCSQLFAIPLVRTLSGYVKPRHTQIRVRLAEDIKLGDRPEYVRAYLEDLGNKQCPVAHITGNQISSNIGSLVGAEVLLMLPMKLDGKEYVSKDETVKAMVL
The following text describes a protein:
Function:
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
Sequence:
MPVAAYIEERVKIPENVQVEINNNEVVVKSGGKELRRRFEHPKIVIKKEGDEIVIFCEYPRRKDKAMVGTIRAHINNMIKGVTEGFTYKLKIRYAHFPMKVSVKGNEVIIENFLGEKHPRRARIMEGVTVKISGEDVIVTGIDKEKVGQTAANIEQATRIKGRDPRVFQDGIYIVEKAGKAI
The following text describes a protein:
Function:
Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
Subcellular Localization:
Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSSMRGLVQFIADLRNARARELEEKRVNKELANIRQKFKAGNLNGYQKKKYVCKLLYVYIQGYDVDFGHLEAVNLISSNKYSEKQIGYLAVTLFLHEQHELLHLVVNSIRKDLLDNNELFNCLALHAVANVGGREMGEALSTDVHRLLISPTSKAFVKKKAALTLLRLYRKYPGIVQNEWAERMISLMDDPDMGVTLSVTSLIMALAQDRPEEYKGSYIKAAQRLKRIVVDNEIAPDYLYYRVPCPWIQVKLLRLLQYYPPSQDSHVREIIRASLQQIMTTAMDTPKNVQQNNAQNAILFEAINLLIHLDTEHNLMMQISSRLGKYIQSRETNVRYLGLEAMTHFAARAETLDPIKKHQNIILGSLRDRDISVRRKGLDLIYSMCDTTNAAPIVNELLRYLQTADYAIREEMVLKVAILTEKYATDAQWYIDITLKLLSLAGDHVNDEVWQRVIQIVTNNEELQAYAAHTLLGYLKTDCHESLVKIGCYVLGEFGHLIADNEGSSPIEQFLALQGKMITSNDNTRAMILSSFIKFVNLFPEIKPQLLHIFRLYSHSPDTELQQRAFEYLTLATLPTDDLLRTVCDEMPPFSERTSILLSRLHQKTAGTTEKKTWVVGGKDANADKKEVLLAQNTGLKRTFTTIVNGTKTGANGSAATSNASGDLAGLDLSAPPAPPPNMASAAHLTPDWEPGYNRLYFADEGVLFEDAQIQVGLRSEYRGHMGVVKIYISNKSSFAIGSLTTTLDNPAAPNLKIDSKSLPEPSVPAAGQTQQTLLVEAHGPFSDAPTIRISYLAGALQAYTLQLPVLMHRYMEPSTLSAEEFFKRWRQIGGPPLEAQHTFGVTAKAKNVSETFTRRLVEGFHWRILENVDPNPNNIVGCAVYQSHGGKTGCLLRLEPNYERKMFRVTIRATQEAVPQALAKQMEQKLAQGAPDEMFGSR
The following text describes a protein:
Function:
Involved in peroxisomal proliferation. Could participate in peroxisomal elongation or fission. May be involved in parceling of peroxisomes into regular quanta (By similarity).
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MAGILSKPNYNQFLESLIKLLAQTSGKDKIAKILQYGAKLLGYIFLKRSKHWVDVMKKLETTSGSARKVWRLGNTLAEQQKILALFKVKNPFAFLNILALIRQSGMYFYWVFDHLILGTNIGLCKFDTVKLGWYSSVSWFFGLLCSIIIDLNTLAIMLKKEKSLRLTITQNKINANNNNIDTHTITSEVENKAIIDQFNEVIKKKNEIYLNCAKNGSDLIIASTLLKIYPFSQGTIGISGIISALIGAYQMWPK
The following text describes a protein:
Function:
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
Sequence:
MKITIAQINPIIGDIEGNFIKIKDAILKALSDKSDIVVFSELSLLGYPPFDLLKNNIIKNKIEEGVKRILQENFPINILLGAPYFEDNRIYNSIYWIKENKIIKRIDKFYFSNDPIGQGNYFSYGTPDFLEIDNKKIGLFIGDDFIFSSDHSNYKDYLKTSDLILIISSSFYYFGKRQERIEKISQLAKGIEKEVIYVNQVGGNGELIFEGGSLAISKKGELLFEGEIFKEDIKTIDLKNLYPTSSKGEDISFLYDGLVLGVRDFIKKSGFQKAVIGLSGGIDSALVACIAREALGEENVLGVSLPSIYTSRESIEDAEKLSKNLGIEFRIIPISDIFYSYLKELNPSGNPIMDVAEENLQSRIRGNLLMFISNREEYILLATGNRSEALTGYCTLYGDTAGALEVIGDIYKTTVYELANYVNKNNEIIPQNILAKAPSAELRPGQKDEDSLPPYSILDPILKAYVDENKSLEEIVQMGYKREIVKTVIEKVERSEYKRRQIPPVLRIRSKNPLKERIFPLVYKII
The following text describes a protein:
Function:
Required for hydroxylation of C-4 in the sphingoid moiety of ceramide. Catalyzes the conversion of sphinganine to phytosphingosine in sphingolipid biosynthesis. Involved in the response to syringomycin.
Miscellaneous:
MISCELLANEOUS: Present with 54300 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MNVTSNATAAGSFPLAFGLKTSFGFMHYAKAPAINLRPKESLLPEMSDGVLALVAPVVAYWALSGIFHVIDTFHLAEKYRIHPSEEVAKRNKASRMHVFLEVILQHIIQTIVGLIFMHFEPIYMTGFEENAMWKLRADLPRIIPDAAIYYGYMYGMSALKIFAGFLFVDTWQYFLHRLMHMNKTLYKWFHSVHHELYVPYAYGALFNNPVEGFLLDTLGTGIAMTLTHLTHREQIILFTFATMKTVDDHCGYALPLDPFQWLFPNNAVYHDIHHQQFGIKTNFAQPFFTFWDNLFQTNFKGFEEYQKKQRRVTIDKYKEFLQERELEKKEKLKNFKAMNAAENEVKKEK
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
Sequence:
MTQTGLYLLTTLPSGTQTADGYDFERIQSKSEGLAECYKSMIPTQLKFESLDSLMTLSDDLVRIDSSVGTVVRRLCNTWVDVNKEIQFNDKWNETDLTQFRWDEKKYPFTETAKVLTNRIYKDIQQIEVRLRDLVSKYQTTSRELAIENKKETGTLLTRRLDSCVPDDVIVDTEYLMTVFVVISKQQHKEFLKIYDTLNEFVVCDSAIQVIVDNDFELYRVVIFRHALDDFKNECRTYHYSVREFKREVANIESAKSSLEESLESQKTTLVRYCEANFVHVLHAWFHMKILRLFTDSVLHYGLPTKYDLIVMRLKKRENKKLMKNLVGKRPTIGTEVNYLPTREDLGYDPEGADSTFPFVFTSVDIGYLVNPLLLVSR
The following text describes a protein:
Function:
UDP-glucose-dependent glucosyltransferase catalyzing the C-glucosylation of 2-hydroxyflavanones (2-hydroxynaringenin, 2-hydroxyeriodictyol and 2-hydroxypinocembrin) and phloretin. No activity with flavanones, flavones or flavonols. Exhibits C-glycosylation activity toward 2',4',6'-trihydroxyacetophenone and phloretin using UDP-glucose as sugar donor. Can use UDP-galactose as sugar donor, but catalytic efficiency is 14-fold lower toward UDP-galactose than toward UDP-glucose.
Sequence:
MMGDLTTSFPATTLTTNDQPHVVVCSGAGMGHLTPFLNLASALSSAPYNCKVTLLIVIPLITDAESHHISSFFSSHPTIHRLDFHVNLPAPKPNVDPFFLRYKSISDSAHRLPVHLSALSPPISAVFSDFLFTQGLNTTLPHLPNYTFTTTSARFFTLMSYVPHLAKSSSSSPVEIPGLEPFPTDNIPPPFFNPEHIFTSFTISNAKYFSLSKGILVNTFDSFEPETLSALNSGDTLSDLPPVIPIGPLNELEHNKQEELLPWLDQQPEKSVLYVSFGNRTAMSSDQILELGMGLERSDCRFIWVVKTSKIDKDDKSELRKLFGEELYLKLSEKGKLVKWVNQTEILGHTAVGGFLSHCGWNSVMEAARRGVPILAWPQHGDQRENAWVVEKAGLGVWEREWASGIQAAIVEKVKMIMGNNDLRKSAMKVGEEAKRACDVGGSSATALMNIIGSLKR
The following text describes a protein:
Function:
Together with Xaut_5043, catalyzes the reversible isomerization between pivalyl-CoA and isovaleryl-CoA, using radical chemistry. Does not exhibit isobutyryl-CoA mutase (ICM) activity.
Sequence:
MIHAGTRPLRVLVTKIGLDGHDRGSRIVAAYLRDAGMEVIYTPPWQTIPGVVKLATEEDVDVIGISSLATDHLIVPKMMEALRAAGLGHVGVVVGGIVPEAEQSALAAAGVSRVFGPGAAREEIVECVTALGQKSRAERVDDYSEANP
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit; With S5 and S12 plays an important role in translational accuracy.
Sequence:
MGDIRKHRKKYERPYKPWDRRVLEETNRLAGYYGLRNKRELWRMSFLAKKYRRIARQLLAAPKSESWKVEPIIKKLQALGILSKDATLDDLLDLSVEQFLERRLQTIVWRKGFAKSPYMARQLITHGHIRVNGRRIRQPSYLVKIEEEDKIECLHPSCLEVEKEVR
The following text describes a protein:
Function:
Plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues.
Subcellular Localization:
Nucleus.
Domain:
The C-terminal part is sufficient to function as an AP endonuclease.
Sequence:
MNPFVNLFIQHSKKQIFLNNNKNNILLNFNSKLYSTITYKNNNNNNNNQIINNKTIMKRKNNEIIQTEEDDDNDNGGIHDCDSCDEVDNEEIIPESPPSKKLQQQQQQQQQQQSKLKPKQTSITDFFSPTVKTSKADKISPFFSNVNNASTTNTTTNNKNVNKKTTTTTTTKKRNNKDEENEDDNEEEEEEEEEEEDKKSKKKTTTTTTTTTTTAYKKKSSPKKKKVNPTENKFSTINYKDDQYVQKEEYSSSKKEKLENVKIGGHVSIKNGYPTLIQSVVAQGFKAVAFFTNPPRTWKHHTVKLDDSIKFKQSCKSLNFDVNCILPHGSYFLNLGSPNKENLQKSRDLMIHEMKNCEILGVKHFNFHPGSHLNEISESESIKIVAESLDYILERTKDVVAVIECTAGQGTNLGYTFEHLRDMIALVKDKTRVGVCLDTCHMFAAGYNISTKSNCDVIFQEFDKVVGFKYLKGVHLNDSKSTCGSKLDRHENIGKGHIGTPCFKYLVNDKRFQNIPMILETVGPYDQEVKLLYSFIEDDDKK
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (By similarity). Functionally interacts with the 5'-UTR of mitochondrial mRNAs (By similarity). Specifically plays a role in the translation of cob1/cytochrome b and cox3. Has a role in meiosis.
Subcellular Localization:
Mitochondrion.
Sequence:
MKFPDLLRCSRAVSLARPDLPRNSPDVYDTKIPILQAITAKKCQRFRGDWGAKRKLPILKNRHISIQKFDTFEHQCAFISSDRFVRTLKRIYDLKLPVPLNDYEQISPYLLQKYNTFSSSNPKSRPTLPPGILYAKLKLLDSFSDSEKKRLSLVSFIQTKKVPLPFTYGKFAPDSKECLFGVSGVIAATSLKGITSTKNRYVIRSLNVDETGKTIPNITRENRSI
The following text describes a protein:
Function:
Necessary for protein translocation in the endoplasmic reticulum.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MNAAPVIVGGMRTPARRRQSNASANGNNSKQRRNSNGNSNSIVKFYGDDSPGFKLTPQTVLISTLIFMASVVILHIISKI
The following text describes a protein:
Function:
May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Domain:
Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
Sequence:
MRMDIVSTNSENLLSSFPPILRQNFKELFLHGKIGLTPIALNDVRPSKYYVRNNQSYGYSYTIKVPYASKRLNWELIFCPEDLKFAPDFNFNDETFYLAYDINSIIENVPSLEQWNVYDAKSLITVLKQFLSLYKKQQLERLSDNIYAHVNLEYQSLVREVNPHDVEIYLEHTCAHFLISVKVDVSALPEYLQPIMNGQNDDYLNPGDDTCYLKVSFVKLDGSRVNTSLQLSPRIDQLINRKTFHFPDFVKHSSLPEYVTTVTNLLQEHIEQLVIYHKLKKEFMTCLCTMYAESVLEFDSEKFDKAEILLEVDDYHCLVQIEINQTFPEEKPTVTLIAINCHPLANTCREKLDYEYNPHWTPEEMLAKLMDSLGENIQRFENHKHA
The following text describes a protein:
Function:
Accessory protein required for glutamate-gated currents. May participate in the gating of non-NMDA (N-methyl-D-aspartate) ionotropic glutamate receptors such as glr-1.
Subcellular Localization:
Postsynaptic cell membrane; Single-pass type I membrane protein. Synapse. Note=Colocalizes with glr-1 at the cell surface. Enriched at postsynaptic membranes.
Sequence:
MCRRAEDLVLLLIPILFGYFSHASEHECKCVLFNVTSGNFHSPEFPAPLEGVPCLFYHFQAPPDHIIRLTFDVFQLPPRIGVCSSSIMLFDHSTDGLIEFGERADFEFCGKEISSGRQFFSKDQHFLLQISSGKESSRGFRGSFLAIPKKNFTSDAVEMAECSYRVEKQKAIIYSPDYPYYYPSKVNCTYHIPQRKGFQIVVNSIVMDIGRDAILQIFESVEGKFEKRLIEMVTSVQKSIYVSSTSSLLIYFSAGNNDVERAVGFVIELQYSNAVWSQSPETASECQLNINSENFKEGQLSSDKIGRFTSSSLPTKCQIVLQGYPNEKISVKFTHFNLYVPDNKNVTKRCTEVDNLSADVRVGSRLSRIDEWCGKRAPPNLMSSSNLLQLEYNTKSSKAIRESTNDDIGFRLDYKFHTDWNMGNMKAKVDKKKECRFSFNSSEHTNGKLWSANYPGLYPRNLYCEYIFHGRNDQVVHIHFEYFDIEGFNQCDETTQSDYILFSNYQTHDRTNRRFCGKTAPKGPILSESNYFRMIFSTNDIFDATGFYAHYQFITQEKSQISRVKLTISSSQTPFSSFFLVILLFTFRYIANIF
The following text describes a protein:
Function:
Essential transporter for growth and development under abiotic stress. Mediates shoot branching by promoting the outgrowth of lateral shoots. Required for salt tolerance via Na/K homeostasis, at least partly by regulating SKC1/OsHKT1;5. Necessary for hypodermal suberization of roots, which contributes to formation of the apoplastic barrier.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSSSFRSRRTLPIEEDGEDAPRADLLPGHQRSDRRSASSTNLDQHVVLGSHSPGHVVVDLRPTAANVDGGGKLELDPVGRMPVHFVLAFHDLTYNVGRPRRMAFWRRSRHVETDATTARGGGARAREGALLLDGVSGEAREGEIMAVLGASGAGKTTLIDALADRIQRDSLRGAVTLNGEPLGGRMLKVISAYVMQDDLLYPMLTVAETLMYSAEFRLPRSLSASKKATRVQELIDQLGLRAAANTIIGDEGRRGVSGGERRRVSIGIDIIHDPIILFLDEPTSGLDSTSAFMVVKVLQGIAKSGSVVIMSIHQPSYRIIGLIDRLMFLSRGRTVYYGPPASLPLFFSEFGHPIPDGQNPVEFALDHVRQLEAIPEGTDELVEFSKAWREKALARGHQNEHRPWQAGVGRHHEHRRQRHRGGGGVHGQSGDVREPVVGGGVGAGAAGVHQHAAHAGAVPDPAGHGGGDGVHPCHRVLAAGQHTQGRERAVRLLRHRRVHHVLHQRRRAPGVPRGALHLPPGDGAQRLQAVLLHGLQRHRRLPASGRALPRLHGHHLLRRRPRRRRRGFPLLRPHRARLLLGRERLRHVPLRRGPPRDHRVHGGGGRAGLLPPPERILHHPRPHPELLDMAALPVADQVPVRGGDAERVRGGGREVLHARGADVRRDADGEAAGGDEGEGAGGDEQVHGVGTEQRLVHHDGAGHTGEAGGDGARQVELPLGHRRVGFPLPRALLPHACAREQEQEEVNARAAMCSSCDRLVVDRLRW
The following text describes a protein:
Function:
Transcription factor that binds to DNA at the consensus sequence 5'-ACCAAAG-3'. Acts as a transcriptional activator. Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Involved in the differentiation of naive CD4-positive T-cells into peripherally induced regulatory T (pT reg) cells under inflammatory conditions. Binds to the promoter region of the FOXP3 gene and promotes its transcription, and might thereby contribute to pT reg cell differentiation in the spleen and lymph nodes during inflammation. Plays a redundant role with SOX4 and SOX11 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MVQQRGARAKRDGGPPPPGPGPAAEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGGGGGGSRLKPGPQLPGRGGRRASGGPLGGGAAAPEDDDEDEEEELLEVRLLETPGRELWRMVPAGRAARGPAERAQGPSGEGAAASAASPTLSEDEEPEEEEEEAATAEEGEEETVVSGEEPLGFLSRMPPGPAGLDCSALDRDPDLLPPSGTSHFEFPDYCTPEVTEMIAGDWRSSSIADLVFTY
The following text describes a protein:
Function:
Plays a role in regulating basal-level expression of CUP1. Activates EGT2 transcription in the absence of SWI5.
Miscellaneous:
MISCELLANEOUS: Present with 538 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MDNVVDPWYINPSGFAKDTQDEEYVQHHDNVNPTIPPPDNYILNNENDDGLDNLLGMDYYNIDDLLTQELRDLDIPLVPSPKTGDGSSDKKNIDRTWNLGDENNKVSHYSKKSMSSHKRGLSGTAIFGFLGHNKTLSISSLQQSILNMSKDPQPMELINELGNHNTVKNNNDDFDHIRENDGENSYLSQVLLKQQEELRIALEKQKEVNEKLEKQLRDNQIQQEKLRKVLEEQEEVAQKLVSGATNSNSKPGSPVILKTPAMQNGRMKDNAIIVTTNSANGGYQFPPPTLISPRMSNTSINGSPSRKYHRQRYPNKSPESNGLNLFSSNSGYLRDSELLSFSPQNYNLNLDGLTYNDHNNTSDKNNNDKKNSTGDNIFRLFEKTSPGGLSISPRINGNSLRSPFLVGTDKSRDDRYAAGTFTPRTQLSPIHKKRESVVSTVSTISQLQDDTEPIHMRNTQNPTLRNANALASSSVLPPIPGSSNNTPIKNSLPQKHVFQHTPVKAPPKNGSNLAPLLNAPDLTDHQLEIKTPIRNNSHCEVESYPQVPPVTHDIHKSPTLHSTSPLPDEIIPRTTPMKITKKPTTLPPGTIDQYVKELPDKLFECLYPNCNKVFKRRYNIRSHIQTHLQDRPYSCDFPGCTKAFVRNHDLIRHKISHNAKKYICPCGKRFNREDALMVHRSRMICTGGKKLEHSINKKLTSPKKSLLDSPHDTSPVKETIARDKDGSVLMKMEEQLRDDMRKHGLLDPPPSTAAHEQNSNRTLSNETDAL
The following text describes a protein:
Function:
Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum. Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane. Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAVVGNAVPCGARPGGARGSGSPQPGRPGLAAGPALIASGDELVAAVWPYRRLALLRRLTVLPFAGLLYPAWLGAAASGCWGWGNSWTQIPEAALLALATICLAHALTILSGHWSVHAHCALTCTPEHDPNKVTFVKVVPTPNNGSTELVALHRDKGEDGLEVLSFEFQKIKYSYDALEKKQFLPVAFPVGNAFSYYQSNRGFQEDSDIRAAEKKFGSNKAEMAVPDFSELFKERATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDDIVPGDIVSIGRSPQENLVPCDVLLLRGRCIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADARLHVIFGGTKVVQHIPPQKATSGLKPVDNGCVAFVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLRDGKEVTPVSSIPIETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQCPPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIDKAHTLILHPPSEKGQPCEWRSIDNSIVLPLTLGSPKALALEHALCLTGDGLAHLQAVDPQQLLHLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVALLANAPERVVERRRRPRDSPVLSNSGPRVSRSTKQKSALLSPEEPPASHRDRLSQVLRDLEDESTPIVKLGDASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKFSDFQATLQGLLLAGCFLFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFSVHFLSLVYLYREAQARSPEKQEQFVDLYKEFEPSLVNSTVYIMAMAMQMATFAINYKGPPFMESLPENKPLVWSLAVSLMAIMGLLLGSSPDFNSQFGLVDIPVEFKLVIGQVLALDFGLALLADRVLQFFLGTPKLRVPS
The following text describes a protein:
Function:
May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix. Secreted.
Sequence:
MAPLFLPLLIALALAPGPTASADVLEGDSSEDRAFRVRISGNAPLQGVLGGALTISCHVHYLRPPPGRRAVLGSPRVKWTFLSGGREAEVLVARGLRVKVSEAYRFRVALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFARAQEACARIGARIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGLVDPDDLYDIYCYAEDLNGELFLGAPPDNVTLEEATAYCRERGAEIATTGQLYAAWDGGLDRCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPNKYSRFNVYCFRDSGQPSTTPEASXPASDGLEAIVTVTETLEELHVPREAVESESRGAIYSVPIVEDGGGARSPP