lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Kinase that plays a role in the adaptation to sustained nitrogen starvation. May act by indirectly repressing the transcription of the two toxin/antitoxin modules mqsR/mqsA and dinJ/yafQ, which positively impacts the expression of rpoS, the master regulator of the general bacterial stress response. In vitro, can phosphorylate the isocitrate lyase AceA only in the presence of malate, suggesting that it may play a role during glucose to malate shift. Displays autokinase and casein kinase activities in vitro. It can also phosphorylate specifically a 65 kDa unidentified cytoplasmic protein (Ref.5).
Subcellular Localization:
Cytoplasm.
Sequence:
MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLMAIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEKKQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQILEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDENNQDISALVGKVDIRKLEHYAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLRISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGESLKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVLEQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARANNSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKGYTRKQVRLLCEWYLRVRKSS
The following text describes a protein:
Function:
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
Miscellaneous:
MISCELLANEOUS: Present with 1840 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MVKLAEFSRTATFAWSHDKIPLLVSGTVSGTVDANFSTDSSLELWSLLAADSEKPIASLQVDSKFNDLDWSHNNKIIAGALDNGSLELYSTNEANNAINSMARFSNHSSSVKTVKFNAKQDNVLASGGNNGEIFIWDMNKCTESPSNYTPLTPGQSMSSVDEVISLAWNQSLAHVFASAGSSNFASIWDLKAKKEVIHLSYTSPNSGIKQQLSVVEWHPKNSTRVATATGSDNDPSILIWDLRNANTPLQTLNQGHQKGILSLDWCHQDEHLLLSSGRDNTVLLWNPESAEQLSQFPARGNWCFKTKFAPEAPDLFACASFDNKIEVQTLQNLTNTLDEQETETKQQESETDFWNNVSREESKEKPTVFHLQAPTWYGEPSPAAHWAFGGKLVQITPDGKGVSITNPKISGLESNTTLSEALKTKDFKPLINQRLVKVIDDVNEEDWNLLEKLSMDGTEEFLKEALAFDNDESDAQDDANNEKEDDGEEFFQQIETNFQPEGDFSLSGNIEQTISKNLVSGNIKSAVKNSLENDLLMEAMVIALDSNNERLKESVKNAYFAKYGSKSSLSRILYSISKREVDDLVENLDVSQWKFISKAIQNLYPNDIAQRNEMLIKLGDRLKENGHRQDSLTLYLAAGSLDKVASIWLSEFPDLEDKLKKDNKTIYEAHSECLTEFIERFTVFSNFINGSSTINNEQLIAKFLEFINLTTSTGNFELATEFLNSLPSDNEEVKTEKARVLIASGKSLPAQNPATATTSKAKYTNAKTNKNVPVLPTPGMPSTTSIPSMQAPFYGMTPGASANALPPKPYVPATTTSAPVHTEGKYAPPSQPSMASPFVNKTNSSTRLNSFAPPPNPYATATVPATNVSTTSIPQNTFAPIQPGMPIMGDYNAQSSSIPSQPPINAVSGQTPHLNRKANDGWNDLPLKVKEKPSRAKAVSVAPPNILSTPTPLNGIPANAASTMPPPPLSRAPSSVSMVSPPPLHKNSRVPSLVATSESPRASISNPYAPPQSSQQFPIGTISTANQTSNTAQVASSNPYAPPPQQRVATPLSGGVPPAPLPKASNPYAPTATTQPNGSSYPPTGPYTNNHTMTSPPPVFNKPPTGPPPISMKKRSNKLASIEQNPSQGATYPPTLSSSASPLQPSQPPTLASQVNTSAENVSHEIPADQQPIVDFLKEELARVTPLTPKEYSKQLKDCDKRLKILFYHLEKQDLLTQPTIDCLHDLVALMKEKKYKEAMVIHANIATNHAQEGGNWLTGVKRLIGIAEATLN
The following text describes a protein:
Function:
Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
The following text describes a protein:
Function:
Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
Subcellular Localization:
Secreted.
Sequence:
MAVCSSSSLILLTVFLSVAVETRPSSDRDEEQVLKSLFGPHLTSLILAPPTSNDSTEGSSGSPEPPTPSEAPVLIHGDRGTASQILRSFLRQREKTRRWGRKPMVAGGGCFGMKMDRIGSISGLGC
The following text describes a protein:
Function:
Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSFRGRGGFNGRGGGGGYGGRGGGGGYGGRGGGRGGYGQGGGRGGFGRGGGRGGFNRGGYDQGPPESVVEVGEFMHPCEDEMVCKCITQENRVPYFNAPIYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKLYIDPAKLLPLQRFLPRPPGEKGPPRGGGRGAGRGGGRGRGGGRGGGGFRGGRGGGFGGGFGGGGGGFRGNRGGGRGFRGGR
The following text describes a protein:
Function:
Involved in cytokinesis. May hydrolyze GTP.
Subcellular Localization:
Cytoplasm.
Sequence:
MSHQQQQAHFDISSNSTLTTNTIATTTNASVSSSPQLNKAQMAIAEAMALKMHEEEKKKREEKKRKRDNEELLSKQVRTKLENERKKLDDSESINASTNQELYSLFNDLQMISHDHNISFDTPELVVVGMQSDGKSSFIESLLGFQFNIVETNIGTRRPLIIQMINNPSKQQPSCRFKKEDYSNSYGGSSSSTSTTSGNSNHNTDKQQNVSSSQGGGGGSNNLNEDKWEEYETPVNELTEEIIRRTNERTGRAGDRVSSIPIFLRVEFAHCSNLNIYDTPGFRKGGDERLKYEISEMVKKLIEPKNRIIVCLEQSNVEWANTISRPLVKKIDPDFSRTILVNTKFDNRVKELRNRESAHKYLEGEGIIAQKKPFFISLPLKRNLETHRFKDAMKETFLDDYRKLLEIGFDENRFGGQIGIYKVRQYVENLLHEKYQQNLLPSMLQLESICKKTEADIVRVKKELSDNNIVTLKEKVMRFVSNFNGQIERLLEGSVVGDPDEFGQTLLQEKENCSVQPWPGYNFDFDIQNSNYSLYGGAQYERLLNEFEFVIHSKEFPETSINEVASAIGVSKSHNSPIYELAATNIFQTKSKKVLLPLIDIVLQRSSYIMKRLFDISVSILGKDENESSHTVSLYEHFLKELQSQYEKFIQTIESECKSRLKDDFEMFTKIVDWNLLSGLTEIKPYNYLKVSPEETKQRVISIMDCKKLEDEPLSRSRNIDDDTYQKVCMIAGRLFSGIRFFFSKLIRNKLNAFFLDPMFQKLGSFVTDYFSKLNDQKYEEMFQLGLKELENKLHKLEFQLIDCKKNRDKFKDVYNRMKQSLNQNQNQNSSSSSNSASSSNNNVIIKHQQSLNGKFSTPDKNSLTMSPFTSPFTQSNYHQHNNNNYQINQQPLDINNDHYFDQN
The following text describes a protein:
Function:
Protein kinase required for the cell cycle where it is involved in mitotic exit. A component of the fear (CDC14 early anaphase release) network which promotes CDC14 release from the nucleolus during early anaphase. Phosphorylates SCC1/MCD1 and NET1.
Miscellaneous:
MISCELLANEOUS: Present with 1480 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Recruited to the spindle pole bodies by CSA1 during metaphase.
Sequence:
MSLGPLKAINDKQLNTRSKLVHTPIKGNTADLVGKENHFKQTKRLDPNNDHHHQPAQKKKREKLSALCKTPPSLIKTRGKDYHRGHFLGEGGFARCFQIKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFRGTFPPSIPSTVMSEAPNFEDIPEEQSLVNFKDCMEKSLLLESMSSDKIQRQKRDYISSIKSSIDKLEEYHQNRPFLPHSLSPGGTKQKYKEVVDIEAQRRLNDLAREARIRRAQQAVLRKELIATSTNVIKSEISLRILASECHLTLNGIVEAEAQYKMGGLPKSRLPKIKHPMIVTKWVDYSNKHGFSYQLSTEDIGVLFNNGTTVLRLADAEEFWYISYDDREGWVASHYLLSEKPRELSRHLEVVDFFAKYMKANLSRVSTFGREEYHKDDVFLRRYTRYKPFVMFELSDGTFQFNFKDHHKMAISDGGKLVTYISPSHESTTYPLVEVLKYGEIPGYPESNFREKLTLIKEGLKQKSTIVTVD
The following text describes a protein:
Function:
E3 ubiquitin and SUMO-protein ligase that plays a role in different biological processes such as innate immunity, inflammation or apoptosis. Potentiates MAP3K3-mediated activation of JUN/AP1 and DDIT3 transcriptional regulators. Negatively regulates MYB transcriptional activity by sequestering it to the cytosol via SUMOylation (By similarity). Plays a role in the phosphorylation of MAPK1 and/or MAPK3, probably via its interaction with MAP3K3. Negatively regulates RLR-mediated innate immunity by promoting 'Lys-48'-linked ubiquitination of TBK1 through its RING domain to inhibit the cellular antiviral response. Promotes 'Lys-29'-linked polyubiquitination of NEMO/IKBKG and RELA leading to targeting these two proteins to lysosomal degradative pathways, reducing the transcriptional activity of NF-kappa-B.
Subcellular Localization:
Cytoplasmic vesicle. Cytoplasm. Nucleus. Note=Colocalizes with MAP3K3 to vesicle-like structures throughout the cytoplasm.
Sequence:
MSSGKSARYNRFSGGPSNLPTPDVTTGTRMETTFGPAFSAVTTITKADGTSTYKQHCRTPSSSSTLAYSPRDEEDSMPPISTPRRSDSAISVRSLHSESSMSLRSTFSLPEEEEEPEPLVFAEQPSVKLCCQLCCSVFKDPVITTCGHTFCRRCALKSEKCPVDNVKLTVVVNNIAVAEQIGELFIHCRHGCRVAGSGKPPIFEVDPRGCPFTIKLSARKDHEGSCDYRPVRCPNNPSCPPLLRMNLEAHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHEMHVALAQKDQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASMLNDELSHINARLNMGILGSYDPQQIFKCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSHNVLFSGSLKAIKVWDIVGTELKLKKELTGLNHWVRALVAAQSYLYSGSYQTIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAVSRGRLFSGAVDSTVKVWTC
The following text describes a protein:
Function:
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
Subcellular Localization:
Nucleus outer membrane; Single-pass type IV membrane protein. Rough endoplasmic reticulum.
Sequence:
MTQEEGEDPVTNYAFQIRSPLTASCFQRPDTGTDTSDPFVSLHFQIFLSSNEMTQMLQSEFETNWENAETWMKTIHERLKINDNTEGPRSALAARLRETEKICALEPEGKLLLDMVLMAAEHLLSKSSEEEKHDIHIKLGKLKSMFEETTVYMTHCHSRIEWVWLHWNEYLKARDEFYLWVHNTKLTLEPDVELQMGIKEKRWHYEQAQVLLRDVNNQSCLLDRLMEEAASLYNRIGDPSVDETVQREMMAEYKQIKKKAKERARYLENILKEHEAYHRDVSEFRSWLNSVIEKLKCGVGEATESTEYWLRMLQEISKEVQNGGKKLEDLEGKSLEVIKNTSPLGADDICKELEELRKALADLKHMNDDEEESLLKAHSSENAFLLLARQLEANINEFRKAIQRLEESLESGERVKSEDELVALWKTLNATKSALAAEETRGEGVKVQLKELFKFSKDVQPLSDGVIAAIREYQRAKSKAFKLSTETESALIQHFQIPLLEFQHWKRICERVLDTTSIPLSDTLLNHDCLLQIERLLEESAKIEDKLRILKTKKEQIIGVLGEQKAEAFLTEVASASRERDSLHVVLLERKKTLLSLASQSKEFDAAFDQLRKKVSTIRIKAGKESELQPDLVGKETQLQRFEMFKDDLLKLEPEFKEVASMAESSPTHKLKVSQLSSEYATLHKSLEINMRKIKAYINDHLIFNGKLLDLQHWLMVTRQELESFQDSNGHWDVESREKEIQILLSEITEKDIQLQQVESQGLLVMETSSPEGAAHIQTELRQLNASWVSLKLLWDALARAFKDRELQRLALLPPTITFENSINQRTDLLPNMELRWTTSQCDNGNNERNNSNDSEEFGPSGIVGRIVYDTSPENATLRSEKSRIPQRKSKTPNVIHENDPLFTTAEFEKSSLSLEINTSITSDSIPSKITVRTDKSRIPMRINQTSSVLQGNSSSFPPGESGKSPSTLESGPTSETVSLDSSQIPRRRAQVSSLLQVTDPLIPSADAKESSSNYIGNVEDPVSTSGESGQSSSTLNINTGFLSGSPNIPVKAPSPYNIVSVRKNKKGISLAESVDFVDSSPVQSKEQKRTESCDGYMDLLKEFELWLQEENSKLNTICSTKTSNSEEMKFRLSKLQRLQLQVPKGQRLFESLLVSVPAMAVTDNLRLEDLRYQWMLYKSKLKDAGSSSRIKTSEELRGITKKSSGGLCSFLHRVCCAALPLQLLLLFLLLLALLILLMQENQNCALSNNFARSFNLMLKYERPPPT
The following text describes a protein:
Function:
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
Sequence:
MGERLGIFGGTFNPVHRGHLAMARAARDRCGLDQILWVPAAQPPHKPLAGGASIGDRVEMVRLAIAGEAGMALSLVDARRPGPSYAIDTLRLLEEQYPQAQWHWLLGQDGLADLPGWYRAAELIPRCRWIVVPRPGSGADPKQAMADLTERFGAVFVPLSDFECDISSTRVREQLAAGRAGWEALLPEQVVSYIHKRGLYDVPAGA
The following text describes a protein:
Function:
Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Membrane.
Sequence:
MNLIQYFRDAREELSRVTWPSRQDVLEGTQAVLIFVVALTLIVWALDLLFGTAIKAALAWR
The following text describes a protein:
Function:
Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasmic vesicle, clathrin-coated vesicle.
Sequence:
MGSTETRHPPAMFDWFFEAGCPNSLEEDPPILRQFPPDFQEQEAMQMVPRFCFPFDIEREPPSPAVQHFTFALTDLVGNRRFGFCRLRAGARSCLCILSHFPWFEVFYKILNNVGDLLAQNQVAEAEELLQNLQQHPLLGPRFSGRSEMDSSITVRSECGILPPALGNSKLLSCFVAPDAASLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTACVHASCALLYPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHGSLAERVREKALEDVVVLNADSNTLETPFDDVQALPPDVVSLLRLRLRKVALSPGEGVSRLFLKVQALLFGGYRDALVCIPGQPVTFSEEAFLAQKPGAPLQAFHKKAVHLQLFKQFIESRLEKLNAGEGFSDQFEQEIIACRGASSGTLRSYQLWVDSLKKGSDALLHSMKTKTQPAVRNMYRSGDSLQEYCASKAKSGLKGMQNLLTIKDGDSGLQRGGSLRTPSLTSRSDRLQQRLPISQHFGQNRPLRPSRRLKTEEGPSEPLRERSPTLSPGDTQNPWAEDTLDGSFLGSGEELDLLSEILDSLNVETKSGDLQRASQSLDCCQRGAASESCSSLPDIPVGLPWQLEEDKRSQDPQPWSLPGDLSLLQDTPFSEVVSYSKNSCSQPFQQSPPSQGDPGPSLSKLDPRPSQSPCPKLLRVPTRHSPPESPQLLVSTEPNSDAVQRLQSISSPSCSHSAENPRNQPPQVLLGQACVQPLEELGAPTYVSHVSTQQRPQDKQPRVADLKKCFEN
The following text describes a protein:
Function:
May be a component of ribonuclease P or MRP.
Subcellular Localization:
Nucleus.
Sequence:
MEHYRKAGSVELPAPSPMPQLPPDTLEMRVRAGSKIRNLLGLALERLEGGSARHVVFSGSGRAAGKAVSCAEIVKRRVPGLYQLTKLRFLQTEDSWVPTSPDTGLDPLTVRSHVPAVWVLLSRDPLDPNEYGYQPPGAPPDLGPTPASSCGPQPRRRARDTRF
The following text describes a protein:
Function:
Acts as a magnesium transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MLTQDRREALLAIEGLASLKTELNNMNPADAGDYIASLPPKDQAIAFRLLAKSRAASVFEYLPSEVQEMLTESLHAREVQAIVEQMSPDDRAELFDELPARVVKRLLTQLSPSEREATALILGYPEGTAGRVMTTEYVRLRQDLTVSQAIQKIRKLDQDKETIYYAYLTDAERQLLGVVSLRQLLFAEPDTPVRTLARETIISVPTTADQEEVARLMKRYDLLAMPVVDLEGRLVGIVTVDDVVDILEEEATEDIQKLSGIIGGDEEALSSPIETVKKRLPWLLGNIALYMGAASAIAPFQSTISLIPVLAIIMPILANTSGNVGNQAISVTVRGLATGEVNPVDVFKILRKEILAGLVNAAALGLVLGLLTLIWSRPEEQWVGIVAAMVMAVNVLVAASLGTFLPIILKRFKQDPALVSPPLLTTTLDTFGFFTFLGLTSLFLVYFKVG
The following text describes a protein:
Function:
Stimulates the secretion of gonadotropins.
Subcellular Localization:
Secreted.
Sequence:
MGIKRALWWMVVCVVVLQVSAQHWSHGLNPGGKRAVMQESAEEIPRSSGYLCDYVAVSPGNKPFRLKDLLTPVAGREIEE
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MAPANAIVAKDGSGQFVSIQEAIDAAPLKSRTMHVIYIKQGIYDEAVVVPKAVTNLAFLGDGIDKTIIQGQRSVAGGSTTFGSATLAINGRGFVASHLSVRNLAGPKGRQAVAVRVSGDQAAFYRCSFNGYQDTLYAHSSRHFYRECVVSGTVDFIFGNAAAVFQRCNIQALLPDPGQNIMITAHGRVTDLQNTGFSFHGCRVEGSGRLVAQSHRFPAYLGRPWKDYATTVFMQSDIGGIIYPAGWSEWEGAPLHRYKTVFFGEYLNTGAGASQSGRVYWSVPSLTMDQAREFTVGKLISGLDWLPYSGVVFANNL
The following text describes a protein:
Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MNQVYFLDIFMFVFVLQFLFYFKESMLNTLVKKFLNSLVGVFSYTNTLPLSSVISIFTFIVLLTCCFGGYFTYSFCPCGMVEFTFVYAAVAWLSTLLTFISSEKFSVYMSKPGDTYLKTLSMLLIEIVSEFSRPLALTVRLTVNITVGHLVSMMLYQGLELSMGDQYIWLSILAIMMECFVFFIQSYIFSRLIFLYLNE
The following text describes a protein:
Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Subcellular Localization:
Late endosome membrane; Peripheral membrane protein.
Sequence:
MYQPYLQQAVQSLQTLSSDELRQLLEDDEKLDERVNEAVQSLESSKDLIIGENRSLAETNLNFEPKMVELRSRVQELAEECRTLGESVKEKSTQLASKSEKNNAETVLALLQTAAAESEEESEKIVKQLLDSELTVDAYVEQFMSIRKLMHSRKLKAEKMTELLRSNRHTTQRFDAGYGPSSMPYPASEPARPGSFYVPPGMAAPSTAVPYPVGPSSMPMPMAMFRPPQF
The following text describes a protein:
Function:
Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MLTNQTIIFNSLKQSIKPSSHLLTIRRTASTNPEQPSSEPIPSTSTTTHTQDNLLKSATSHSDAHRTKTINHLSNSAYLKPIKQQFRSIKTSLSHQFADFPSKLSQLTGYGDIDKLKSLVSQTEANLRASREDAVQAKIKYNLAAQRRAESIKEVNDLLARKASWSDQDLARFTTLVRTDHSNEQAESEAKKGLEESEAKVDHQFTNMMQAILTRYHEEQVWSDKIRALSTTFSLSITLINVLVFLAAIVLVEPYKRSKVVSEVEDRIVKRDMNNTDILDRALNTVVDRLSSTEKQLSDLILSLQAPLELPTSPSALPSSTLEDENQVTIVPATTTLPQVTQVENMIPSPISGSRTDPRDELMDSENKSSQQTTQEGSGIEDPAPEESQLSPQPQRSPSWYEKLNQAKDEWLENHDYTSSDQESLKAIGIGTVVGIILLSSYHFFSQ
The following text describes a protein:
Function:
Together with MIND1 and MCD1, regulates FtsZ ring positioning in chloroplasts in an ARC6-dependent manner. Z-ring accessory protein involved in the initiation of plastid division and division site placement (might functionally replace bacterial MinC). Acts as a disassembly factor that accelerates fragmentation and depolymerization of existing FtsZ2 filaments by enhancing FTSZ2 GTPase activity, thus leading to the conversion of FTSZ2 bound GTP into GDP, a process which triggers FtsZ2 filaments destabilization. Prevents misplaced Z-ring formation at chloroplast stroma nondivision sites. May control the rate of chloroplast expansion. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency.
Subcellular Localization:
Plastid, chloroplast outer membrane; Peripheral membrane protein; Cytoplasmic side. Plastid, chloroplast stroma. Note=Distributed in two pools, a first one throughout the stroma, probably to inhibit Z-ring assembly at nondivision sites, and a second one localized to a midplastid ring-like structure. Located at the site of chloroplast division on the outer surface in a ring-shaped structure at the early and middle stages of the process according to PubMed:15356321. Forms ring-like structures, short filaments and discrete foci in the chloroplast stroma according to PubMed:17304239.
Domain:
MORN domains promote interaction with ARC6 and CDP1/PARC6 but prevent binding to FTSZ1, FTSZ2, MIND and MINE proteins.
Sequence:
MPISMELPVFSTLRVPLFSRLALLPTFGVPFSSLGATTRLNCTSRKARRICVMCLVRDSAPIETCERAGEDGSDEFIEVLVIGSRKESIMDSCLDSPFPSLPLRFWSISKDSSGGLVLQQRLNHQDNALKTMNPIELLQSRPRAFILVASAGYGSDQVEAINILSAVRSGGNLAVAVLLKPFSFEGRKRLEEVNELARKLQQHTNFCIDIDIEVLLQKDLVTLDEALRNANNAVSMAINAASALISGMHGNFIDVMHKDLKELEGSEVKTILESYKEAKVGFGVGHNLKTSILRAIYDCPFFRPGLKDLNAIICIVASSVPLQKKDVKTILRTFRQTMEYTGDIIVSTVHEPDLEPKVRVTTFFILSSSEVETSNKGNIFSGLVPFVLNIFTRYRSQLQKETNIGLGETPVSIKDSADSTDVKTSNQNIEEFEIDSEDLLEVSENGDDSEYPLKEGEPSRNSRLDLKDENVEDFGAIQREPIANWSMDQGYQIEQKWQADSGDTAVLSLGIVNLPVGVRPSKKLNSNLSVASQLSRKADSREESFFNPNGSTKDSSDTASTLLSEKYADFTKQRNLSARASSMLEAERDSSKRWSPILEMQYRGGLFKGRCQGGLPEGKGRLVLGDGSIYDGMWHNGKRSGLGTFYFKNGDVFQGTWREDLIHGKGWFYFHKGDRWFANFWKGKASGEGRFYSKSGEIFFGHFKDGWRHGQFLCIDLDGTRYSETWDDGVLIDRKQVDAGD
The following text describes a protein:
Function:
Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.
Subcellular Localization:
Secreted.
Sequence:
MVPPPPSRGGAARGQLGRSLGPLLLLLALGHTWTYREEPEDGDREICSESKIATTKYPCLKSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYRYDRERHRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIREDDGKTCTRGDKYPNDTGHEKSENMVKAGTCCATCKEFYQMKQTVLQLKQKIALLPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHRTHSSAEEFPLPQEFPSYPEAMDLGSGDDHPRRTETRDLRAPRDFYP
The following text describes a protein:
Function:
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
Sequence:
MTRSIAGELQQLREQGLYRSLRTVAGSQGSRVVAEGREVVLLCSNNYLGLADHPSLKRAAVEAVERYGTGSGASRLVSGTMELHAALEERLARFKGTEAALVFNSGYAANSGIIPALVGRGDVVFSDRLNHASIVDGCLLSRARFVRYPHNDMNALERLLAEHRGAGRMLIVTDGVFSMDGDLAPLPALVALKRQYGALLMVDDAHGTGVLGESGRGSAEQFEVAADIDLQMGTLGKALGGFGAYVAASAEVVELLINRARSFIFSTSLPPAVLAAARAALDLVDSPEGKALRRRLARSAALFRDALQEAGFDTMGSETQIVPALVGEAEPAMTFTRRLLEEGFYVQGIRPPTVPAGTCRLRCTLMATHDESDLERAVAAMARIGKELGIV
The following text describes a protein:
Function:
Acts as a negative mediator of apoptosis. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MHFEAEESKEVATDVFNSKNLAVQAQKKILGKMASKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDFTFDRNVLSKLLNECREMLHQIIQRHLTTKSHGRVNNVFDHFSDCDFLAALYNPFGNYKPHLQKLCDGINKMLDEENI
The following text describes a protein:
Function:
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences (By similarity).
Subcellular Localization:
Nucleus, nucleolus. Cytoplasm. Cytoplasmic granule.
Sequence:
MMGSNYPEHGTKPRSAKYHKQQNHRVVRKQPPRPAVSDRHNIYITSKTDFKAQQRRCEELINSGAHEIFLHCMGFSVTRGLNIALRLVQNSDGALSYAINTSTVQLVDELHPLCDAEDITFRQRNNSALHIKILNNSLFDIAVPQPSQSQTQAQSLGQFRGKAKARQ
The following text describes a protein:
Function:
Antimicrobial peptide with modest activity. Active against the Gram-positive bacterium L.monocytogenes (MIC=22.64 ug/ml), B.megaterium (MIC=10 uM), B.mycoides, B.subtilis, M.luteus (MIC=40 uM), M.phlei, and S.aureus, and the Gram-negative bacterium E.coli (MIC=7.66 ug/ml) and P.aeruginosa. Shows moderate affinity to the negatively charged (POPC/DOPG 3:1) lipid vesicles. The peptide interacts with the surface of DPC micelles by two alpha-helical regions. It does not interact with the zwitterionic (POPC) lipid vesicles, which model membranes of eukaryotic cells.
Subcellular Localization:
Secreted. Target cell membrane. Note=Isolated from mesoglea.
Domain:
The peptide interacts with the surface of DPC micelles by two alpha-helical regions.
Sequence:
MGCFKVLVLFAAILCMSLLVCAEDEVNLQAQIEEGPMEAIRSRRAACSDRAHGHICESFKSFCKDSGRNGVKLRANCKKTCGLC
The following text describes a protein:
Function:
Metal transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MIALRIIFFVILIIIWKSYNALSTNPTIKLSGVQNSVQLRVKPDEEFKIRVLGKNLPGRGFFFTSATTCADAFIPNNEKISTIHAIVDETFCSSAILKFPQGLPFKVSKTYHLCHEKGNATSEHFLTIGAVDVLGQKYGMDVIILCCFCILMSAYAAGMTLGYMKFSIVELNTMINGGDAALAKRARRILNLRRRSNYLVTSFSLFSSIFTVLFTTNVEQMLKGAPNQSILNVAVPALISLVFAEMIPQAICNSKLGFNLASGLWFISYLIFIVTFPVAYPVSLVLGRFLKRDVREVLTEEEKNCMIQNMAKNANEKVKTILENATTFTNKKVGELMVPIEEVFMLSKSQKLNRSVIGYLILTILTLIEKGYTRVPVYHDKNRNTIVGLLNVKDLNLVTCQLSVEPMVKEVLDKLEKLKEAKKKVKFMAKYVNIDMNAQLLLNQMRTGDFHFACVVKYASYEYVLIFKRRFEILLLSSSKVIGIITIEDILEELFGKIDENNERKVRSSIDDRADNAVIGWCREAGTDSNYPLPFSQQLRILQYLLKECQVLKSLDIGILKAKQILMLNRIRTFHKGQELPLDDLFIVIWKGDVEVTNAEGETSYESISAPPLWLVSDNLIFIGIDLFSNSNEKEVEEKKPSVPVLIIGKKLLNKVMKSLGSPFLEPLKSSDNVKRVVVLRLEDLLNAINGCVQATKNENANAGDSLIQRLNSRQSTPVSTTPITRTPSKAAEPNPSEDVKPLLN
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MAPPFSSIFVVSLLFLGFFVQAHGHGVQSAAFTYEGSHGPQKWGSLSPSYAACSNGKLQSPVDISKDHSVFGKELQTLARKYSIANATLTNNGFNIGVHFWENSGGTAIIDGKNYILRQLHWHSPAEHRLNGEQYAAELHLIHQAEDGTLSVIAILLQIGEPEPLLAKIQDKLVELANEKCGGDEVAHVALGDLDTKHLRKKTRKYYRYIGSLTTPPCTENVIWNVLGKVRTISQQQLEALKAPLDPVYKNNARPVQPLNGRKIEIYDELSEY