lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.
Sequence:
MAAGGLASRRLTSWAYFRLLPLPPLPPLPPRSSLLPPLPPSLPRPPAAVLPSVAVGGCRRRRGGERPDPPPPRKEPTPGPATVPHRPEGRGTPAGSAPRPGRPAPGPRPVGSHPGAVRPRRGGGMEEAAGGLPLGALAAVLKHSLVVPEESAQVRGYDFNHGLDYRALLKSYSTTGFQATNFGQAVQQVNAMIEKKLEPMEEGEENHADLNPSRRPRSGCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYVGEFSMKGKELRQNGINRIGNLLVPNDNYCKFEDWLMPILDQMVLEQNTEGVKWTPSKMIARLGKEINHPESVYYWAQKNNIPVLSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINSQAVFAKRTGMIILGGGLVKHHIANANLMRNGADYAVFINTAQEFDGSDSGARPDEAISWGKIRMDAHPVKVGCGLALPGSVAGPGPRPPPWWVMAPFLSPASPRSMPTPPLSSPCSWLKPSPRRSMCSPPRRTTTDSTGLSSPSLSVPPGPWPKRSTKSTTLPSFHGLGPVLCLQTASLLAPASPPPPPPESRLPYLPSPAPVPRKSSVKDPGQPRNVPFNESQAHDVTPSPVGASAWDFFGRVRIRPPALDAALGGSEQTGLGGVEGQGLDHAASHRQGQGQGALGREERESRASGSEIDRWPALGDGQPRLRAPPPFRRLPTRGGRERRPLTSTRSQKYTLPFSEPLPT
The following text describes a protein:
Function:
Stimulatory or required for the translocation of secretory proteins across the ER membrane.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGLRKKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVPAAEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFYFSDEKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAVLSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKKRSRSSKKRTENGVGVETSNRVDCPPKRKEKSS
The following text describes a protein:
Function:
Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms (By similarity). Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN (By similarity).
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MNPGAARTPALRILALGALLWPAARPWELTILHTNDVHSRLEQTSEDSSKCVNASRCVGGVARLATKVHQIRRAEPHVLLLDAGDQYQGTIWFTVYKGTEVAHFMNALGYDAMALGNHEFDNGVEGLIDPLLKEVNFPILSANIKAKGPLASKISGLYSPYKILTVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEVDKLIAQKVKGVDVVVGGHSNTFLYTGNPPSKEVPAGQYPFIVTSDDGRKVPVVQAYAFGKYLGYLKVEFDEKGNVVTSHGNPILLNSSIPEDPNIKADINKWRVKLDNYSTQELGKTIVYLDGTAQSCRFRECNMGNLICDAMINNNLRHPDEMSWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQATGEFLQVGGIHVVYDISRNPGDRVVKLEVLCTQCRVPSYEPLRMDKVYKVILPSFLVSGGDGFQMIKDEKIKHDSGDQDINVVSGYISKMKVLYPAVEGRIQFSAGSHCCGSFSLIFLSVLAVIIILYQ
The following text describes a protein:
Function:
Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
Sequence:
MFAGRRVLVAVTGGIAAYKVCEVVSTLAQAGASVRVLLTEAAERFVSALTFATLARARAYTDADFWSAEHGAPLHIALGQWAEVILIAPVTAHTLARLALGLADDLLTNTVLASSAPILLAPAMNTQMWEQEPVAAHAQTLITRPRYHLSGPGRGRLACDAVGAGRLSEPAVLLRHLGSLLWSGGKQDLAGKTVLVTGGGTREFLDPVRFIGNPSSGRMGIELAAACAHRGGTVHLVLGPTHLEAPPEVDCHPVVGAAQMAQATFALFERAHLTFMAAAVADVRPSQIHIDKIPKNQLGNRLTLEPVEDILLELSRRKQPWQTLVGFAAQTGEDWLVPAAAKLKAKHLDWLVANRVDLQEQGFGGDNNQAMLLSSRGDMHAIPLMSKLEMAHRLLDRMETPA
The following text describes a protein:
Function:
Involved in the biosynthesis of furaquinocin. Catalyzes the transfer of a geranyl group to 2-methoxy-3-methyl-flaviolin to yield 6-prenyl-2-methoxy-3-methyl-flaviolin and 7-O-geranyl-2-methoxy-3-methyl-flaviolin in a 10:1 ratio. Can also use other substrates such as flaviolin or 1,3-dihydroxy naphthalene, and can also use DMAPP as prenyl donor.
Sequence:
MPGTDDVAVDVASVYSAIEKSAGLLDVTAAREVVWPVLTAFEDVLEQAVIAFRVATNARHEGDFDVRFTVPEEVDPYAVALSRSLIAKTDHPVGSLLSDIQQLCSVDTYGVDLGVKSGFKKVWVYFPAGEHETLARLTGLTSMPGSLAGNVDFFTRYGLADKVDVIGIDYRSRTMNVYFAAPSECFERETVLAMHRDIGLPSPSEQMFKFCENSFGLYTTLNWDTMEIERISYGVKTENPMTFFARLGTKVEHFVKNVPYGVDTQKMVYAAVTSSGEEYYKLQSYYRWRSVSRLNAAYIAARDKEST
The following text describes a protein:
Function:
Protein-lysine N-methyltransferase. Monomethylates PRMT5, modulating its transcriptional activity. May also act as a histone methyltransferase. Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1.
Sequence:
MCEKSDETRCNLTNILMQLRRHLSVNHNVAALSQRFGALNSNLERVNFVEELIKSAEITIELQKDVKNDEIATKYREKGNEMYKKRKLKEAWEFYTKSVCFAEENSTNLGLAYANRSAVLFELNLHKQCLKDIKRALNHNYPEHLKSKLFVREKNSKNTAIEETCPHEAIPIVTNNNPNIQSASACIAVREEENWGRFVVATRDIKVGEVLAVEKPLVTLVVNELSNHCHECVSLCYNLIPCKTCTQAMYCSESCRDYAFDMYHKYECSILATLRFLQFDKLKLFALKISLQYNDLGETSDLLYRSDRYREIHNLVTNTTKRSVPDLFERATAAALIYDLVKTHTNFFSAFNQNNFKEILLLHMQTGPSNFHEIVELVPNSRGIYEPEEIASGAFAFLSLLNHSCCPNVARFSYGSTLVLRAIQNIQEGEQCFDNYGYHFALMDKSERKKHLQSQYYFNCVCQACEKNWPLFDSLPSFNSHEIEDSVFLKLSSGDVETAVTVAGDLCTKLGELQKLQPCKDFCQLQEIVKQYIVSVVPPKWFGGGTAVPQCAVWSTAPAQPVAKMQLIYFFTLFSFAVSEDLKLTILHNNDLHSRFEETSRNSGTCKDKKECVGGFARTAHEIRRFRTESGDNPVLFLNAGDTYVGTAWFAVHKWKICVEFLNLLKPDVMSLGNHEFDFGVSSLAPFVKNAQFPIVAANLDFTKEPSLSEIKKSVVIDISGRKVGIVGHLTPDTRIMSQPGAVEFLDVVESVKNETQVLDAAGVKIIIVLGHSGYDMDLKIAADVPLADVVIGGHTNTFLWNGAQPDLEKPEDMYPKVVVQKGGKKVPVVQAYAYAKYLGVLNVTFDGQGDLVGFQGQPIFLDNGIVQDQDVLDLLEKYRPAVDEINKEVVGKSAVVLDASANKCRVVECNIGNLIADSFVYYMAGQYAGPGWTDTPIGLINGGSIRTIIDPSVHGGNITRGELMGTLPFDNQVVSFKLTGSQILKTLEIGARSNGETSKGEFLQFSGLHVVYNKKKPAFERVVSVKVRCGNCSVPLYEPLDPKKTYGVVTASFLTNGGDGHEVLANAPNKKVQDLGDVDTVVWYLKRQTEVYPEEQGRIKFVESEGGNTPSGATRTFGVLALVLTLVTKVVIV
The following text describes a protein:
Function:
Virulence effector that plays a key role in hijacking the host vesicular trafficking by recruiting the small guanosine triphosphatase (GTPase) Rab1 to the cytosolic face of the Legionella-containing vacuole (LCVs). Acts as a GDP-GTP exchange factor (GEF) for the small GTPase Rab1 (RAB1A, RAB1B or RAB1C), thereby converting Rab1 to an active GTP-bound state, leading to the incorporation of Rab1 into LCVs. Also shows RabGDI displacement factor (GDF) activity; however, this probably represents a passive activity following the GEF activity. Also acts as an adenylyltransferase by mediating the addition of adenosine 5'-monophosphate (AMP) to 'Tyr-77' of host RAB1B, thereby rendering RAB1B constitutively active. Also has adenylyltransferase activity towards Rab6 and Rab35. Also displays guanylyltransferase activity by mediating the addition of guanosine 5'-monophosphate (GMP) to host RAB1B in vitro; however such activity remains uncertain in vivo. Specifically binds phosphatidylinositol 4-phosphate (PtdIns(4)P) lipids on the cytosolic surface of the phagosomal membrane shortly after infection.
Subcellular Localization:
Secreted. Host cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Translocated into the host cell via the type IV secretion system (T4SS). Membrane association is mediated by PtdIns(4)P-binding.
Domain:
The P4M (PtdIns(4)P-binding) region mediates binding to PtdIns(4)P and membrane attachment.
Sequence:
MSIMGRIKMSVNEEQFGSLYSDERDKPLLSPTAQKKFEEYQNKLANLSKIIRENEGNEVSPWQEWENGLRQIYKEMIYDAFDALGVEMPKDMEVHFAGSLAKAQATEYSDLDAFVIVKNDEDIKKVKPVFDALNNLCQRIFTASNQIYPDPIGINPSRLIGTPDDLFGMLKDGMVADVEATAMSILTSKPVLPRYELGEELRDKIKQEPSFSNMVSAKKFYNKAIKDFTAPKEGAEVVSVKTHIMRPIDFMLMGLREEFNLYSEDGAHLSAPGTIRLLREKNLLPEEQIARIESVYNQAMSKRFELHAEHKKEHDEMPYSDAKAMLDEVAKIRELGVQRVTRIENLENAKKLWDNANSMLEKGNISGYLKAANELHKFMKEKNLKEDDLRPELSDKTISPKGYAILQSLWGAASDYSRAAATLTESTVEPGLVSAVNKMSAFFMDCKLSPNERATPDPDFKVGKSKILVGIMQFIKDVADPTSKIWMHNTKALMNHKIAAIQKLERSNNVNDETLESVLSSKGENLSEYLSYKYATKDEGREHRYTASTENFKNVKEKYQQMRGDALKTEILADFKDKLAEATDEQSLKQIVAELKSKDEYRILAKGQGLTTQLLGLKTSSVSSFEKMVEETRESIKSQERQTIKIK
The following text describes a protein:
Function:
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
Sequence:
MSKRVVTVPLQGGKVAVNPQFQDALKQIGLDPNAVVQRVQEELKKVGKYPVQKVEVEVVSPSKYEVKIYLPPIGDLLLKLFGKDTGAHDARNEVIGNLSFAQLVEIALLKKDELKSKTLKSAVKQLLSTCKAMGVTVDGRKAEEVLRDVDGGKYDEIINKFEKQWQQ
The following text describes a protein:
Function:
Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner. Plays an important role in regulating DNA-replication and common fragile sites (CFS) stability in a RBBP6- and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication (By similarity). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to chromocenters.
Domain:
The BTB domain is not required for activation of transcription or self-association.
Sequence:
MTVMSLSRDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKNIFWSHTICISSHVLELDDLKAEVFTEILNYIYSSTVVVRRQETVTDLAAAGKRLGISFLEDLSDRNFSNSPGPYVVCITEKGVVKEEKNEKRHEEPAVTNGPRITNAFSIIETENSNSMFSPLDLRASFKKVSDAMRTTSLCQERASVCPEAEPVRTLAEHSYAVSSITEAYRSQPLREHDSSSSSGKTGKENGEALTTKAKPCRKPKTQTQDSDSTTENMPLPLVTCPEVNQERSPQPAPILSHSEPPSSEGDVHFPREDENQPSETPGPPAAEVPPLVYNCSCCSKSFDSSTLLGAHMQLHKPTQDPFVCKYCNKQFTTLNRLDRHEQICMRSSHMPMPGGNQPFLENYPTIGQDGGSFTSPDSLVPESRIGELSSAGSALSDADHMVKFVNGQMLYSCVVCKRSYVTLSSLRRHANVHSWRRTYPCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSISKKTANGGLKPTVYPYKLYRLLPMRCKRAPYKSYRNSSYESAQGNRQRNESPPDTFVIPNLPSSEMPTLNFQDGRNSLTSSPAIPVETPSWQGTPTSAKVKNAEGLKWRKQALKTDLVDSAEVSISSIGNSVSTTLQAEPVCVSSGEHSASVISYSGLVPSVIVHSSQFSSVIKHSNAIACLANSNHQSPSQPVASPSLIKDSKPEADKASKLASRPKNSKEKKKTVPCNRGEITEEAKYVADLGGSSGKTTNVVEETSKIETYIAKPALPGTSTNSNVAPLCQITVKIGNEAIVKRHILGSKLFYKRGRKPKYQMQEETLPRESDPETRGDSPLGLCQADCVEMSEAFDEVSDQDSTDKPWRPYYNYKPKKKSKQLRKIRKVKWRKERGSRSPVGRRRYPAELDRAEMGRRRYPAELDRCAEVKLPPDKASEEEENKEMPKLQCELCDGDKAAGAGAEGKPHQHLTLKPYICELCAKQFQSSSTLKMHMRCHTGEKPYQCKTCGRRFSVQGNLQKHERIHLGVKEFICQYCNKAFTLNETLKIHERIHTGEKRYHCQFCFQGFLYLSTKRNHERRHVREHDGKGFACFQCPKICKTAAALRMHQKKHLFKTLTKQEETDDLCHENSDLLESQPCTDSEDSDQKDDIKKPLLKMSFE
The following text describes a protein:
Function:
Required for proper chloroplast development, most likely through regulating plastid-encoded polymerase (PEP) dependent chloroplast transcription. Acts as a component of the transcriptionally active plastid chromosome that is required for plastid gene expression.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAMAAASPFLLLQPLAPKAHRPFGPLHPSLLRTRLLRCSPNGGAAPEPPPKPTPRRGRKKASEPGSSPPKAKATRRKTKKAGQDSDSEGEEEPAAKPKTRRTKKSPKQEAKKQEEEEEEAHAEEPRSAAREEDAGSDGDDGADLPYEWPPLVCCFGAPRWEFVPTVRVSDQQMHPDQYSTWLHLQWEPPEFARSPGSASSNVAIALTRLGGRAAVLGKVGDDDFGHELVYRMNRERVQTRAIRFDGAASTAIARMKVAFQDREDGEGGTCLVAETVKSSAEDSLHKDEINADVLKEAKMLHFNSEVLLTPSMHDTLFRTIELSKKFGSKIFFDLNLPLPLWRSRDETKEFINRAWKEADIIEVSRDELEFLLDHKYYEYKRATPPQYYLDGFHLTRNWPQYYHYTPEEIAPIWHDGIKLLLVTYGTLRIHYYTPKFHGCVVGTEDALITPTTTDRTGSGDAIVAAAIRKLTTCPEMYEDQDTLERELRFAVAAGIISQWTIGAVRGFPTESATQNLKEQVYVPSMW
The following text describes a protein:
Function:
Defense against chitin-containing fungal pathogens.
Sequence:
MTMIGNKSLSMSIAKLAIAFFIMIMVPKSISAQNCGCEEGLCCSQFGYCGNTDPYCGTGCKQGPCYAGRTPPSLPSNDVKFTYYCDESNAEYTCAPNKGFYGCGPIQLSGKDNGSDGLNSPETVANDPVLDETCVSINGRLECDGAKPTTVQTRVGCYTQYCSQLGVAPGDKLTF
The following text describes a protein:
Function:
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MERGPEIGPRVVGQIFGIPITNTLISLQIVSLFVILLAFWLSYKPKETITTRQNIAETLVEMFKRYLSGFLEEHIAEKYFSFFATLFLFILISNWSGFIPGFTSPTSDINVTAGLAIGTILYIQYVAFKERGVEYLKSFVSPSVLFLPINILEQITRPVSLALRLFGNISGEHIVLGIISLLAPLIVPVPIMALNMFMGFIQAFIFTSLSAAYLAAALEE
The following text describes a protein:
Function:
Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTDERDVPLEERLRQKTQGFATHKEAPAPSASGPARRANKNQPLELSSKRAVGRFRQVVDVKKKRSLDPRFEAQSGRLNEDLFAKSYAFVDEYKQRELQELKSQFQKTKGGDKKDELKHEIALRQQEMTEKKKQDKIRSALTKRKREEREAVATGKGAFYLKRKDKKKLELHAKFQDLQDTGRLSKFMAKKRKKNASKDHRWLPTQRK
The following text describes a protein:
Function:
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Sequence:
MIKAIIGKIIGTRNDRWIKQYKKQVLTINALEPTYEKMSDDELQNAFEELKKRVRSTEKDLQEKTLLEVLPESFAITREASKRILKMCHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATLAVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSVGTITASVRDDDERLEIYSKDIVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRMENYNKADEVAKSMQVEIDFTIDEKNRAILITEEGIKKAENLFGVDNLYKIENAALSHHLDQALKANYLFFIDKDYIVANNEVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQTLADITFQNYFRMFSKLAGMTGTAQTEATEFLEIYNLEVVSIPTNLAIKRKDLNDLIYKSEKEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEIIKDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGDPGTSQFYLSLEDNLLRIFGSDRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFESRKHLLEYDDVANEQRKSVYKFRDELLDVNYDISAKIAENREYALNQIFSKLKAFDHQNLSEEELLGLKNILKEDFNAHVSLEDLKKASPIENFVAEKLKSDYENKMKVLDSEQRSRIERIVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLEFIEDIKTEAIKTFSKIQFENEQDSSDAERYLDNFSEEREHESVTYRHEEALDEDLNVAMKAFAKTPKRNEPCPCQSGKKYKDCCAKSGPKKGLFAK
The following text describes a protein:
Function:
Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MYTNYIPSSSSDRAANVEFINSCSFLDTNQVCCGLCGEIVDYDKLLTEHLPHAHPEYQSQEMQLEEIPYTSWLKDRLKRESKFLENGFRNYDDPHQHQIGSSAGFGGAPRLYTRNLRQMRKVSQIRVNVNEMSMSQLETALKRKLIEKMGRKVPVSLVDRLHARCDICQAVVSLNKKFEVIHLVRHFNAWHPAEHRCSQEWKEVAALPNPGARHPLSLHDFAVVSTETDQNNLQCIWCGMFMDRAALGMHFSEIHTQQHFFSGFLTSFRFLAHLEAEIWSFEVLEIIVPNCSLCLQEMVMTARFMEKYGKDFGISLPDEFHLQSSKLGAKYSSEKAMDKAIEKHLKRIAMKGGADQSDGGGGGIDDDDDDQTISITNSQQSFGRRNRLKRKFVKPCFRQVCPPNSEFFEPKSACEWRCRLCNRFVYAAVISAGAIKHFKEFHPAEIDKMQYELVKYVSVQKRANLDYVEPRYSYKLARLFQLFSTKLYTFLSEFQARLERIGDGSMEFVHPQLVECLICNLTYALHKPFNICRAIRHLRLKHPEVMPETSGKSISGAEIAETVNLKAPVMTNPSTASTAAAAKKRPNIRFGDCITDPIELEKFRKENWDQQFDKVQVVYGIKKNDEPAFILLMDNEQMDEKTAMEMAEKEQENGKNLRISESQRLRISEVPESQESQNLRGSEAQNLRISESQNLRISESQNLRISESQNLRISESQNLRISESQNLRISESQNLRISESQNLRISESQNLRISESQNPRISESQNLRISESQNLRISESQNLRISESQNLRISESQNLRISESQNLRIPESQNLRVSESQNIINSESQNLRISDSQNLRISESQNLRISEFQNFRNSEFQNFRNSEFQNFRNSESPEFFEFRIFRCNSTPQTLGNSLWRQHTHNSTDKCDKTVDKYIEQDVVLVVIDLMLQYVQAYRHLLLNVRIQRPERLFVMFWLSHAAEVWIRERENREEQTTMLADQEWMFYRCLLLSAVEISSFVFVILLFWKLKKDETVHTWRQMISLTMLGYYGEQWMGILKF
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MISDFEHFQPSLRKETLDTIKEFGFSKPTEVQKVVIPAFLDRKDVIVQSQTGSGKTLSFLIPLFEIIKRERESIEKKEVYGIIISPTRELAHQIYDIAKIFCKHFNMTIGLLTGGIDISTLEEEMKKGANIVVGTAGRIEEVIVNKLFELEWNNVEVLILDEGDRMIEMGFSQSMTRIICHLPKQRRTGLFSATMPKELNKFVIAGCRNPYKIQISNDNTLTPISLANEYCIVPYEIKMQTLIRVLKESKDKKIVVFVLTCDQVDYIYNIIKILHQEGYLKEKEIYSIHGKVKQVNRDKVIKKFEESCEAILICTDVLARGMDFDNINYIIQYDPPQDPKTYIHRVGRTARMGSIGHSLIFLGPLEKSFILLMEKKNVKIIERTIERNEEEEKEYFNKIREICCKNRTVFKKSQNAFVSFCKGYGEHQCKYIFAIKKLVYNEVAKGMCLVKMPKIQEVKRMGIKYEEEMSIEENEIPFADERLEQQRQERGKKRKEKGV
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSTVELDFFAMENQSSSTPANSTLFRRQRSFKDIQSAISKINPAILKSLIVSGSADHHSDFTVPFAISPKFRSPNSDRNLSTTLPVYSPSESRLSSEIGSDDKYPLTIFYNETVAVFHVSRDEAKSILTFAEKSRSNSNGKSGAEQEKSVAEIPSNQYQQLLDVDPQDEDLPLARKRSLHRFLEKRKERLIPVGPYVCHF
The following text describes a protein:
Function:
Probable polyketide synthase.
Sequence:
MDDEEGVAIIGLGFRLPTSCTNDNADGEYNLKYTPNSFWNSLMNKFDGIVSINERWSENYNKLGEISNNYAGLIPLDEWKSFDPLFFGINPSEVATIDPQQRVLLKCTWEALEDAMIDPIKLRGSNTSVFIGSSATDYQNINIDNDEVYPNIFGVSTYSIASRISYCFNFNGQSVTIDTACSSSLNAIQLGCTSIQNGTSNVSIAGGVNLILNPNISKSFAYLNVLSKTGRCKVFDESADGFVRSEGAGVVVLKNLKQAIKDGNNIYCIIKGSSSNVDGNGLSDKSNFYSPSSQSQADNIKLALKSTNGSVNASDIDYVEAHGTGTPTGDPIELKGISMVFKDHRPHSNAPLLVGSIKSNIGHCESASGVASLIKCCLMFKHQCFAPNIHFNKPTPLINFEESKIKVVTDPIPFNPNKKVSIAISNFGITGSNCCLILSQYKPQAPQHILNQSNKTKKIYHQQYIKSYDRELESPIKRGAKISNSENICQDRLFHQQIDEKVQYLPPITSKLLIPFSANSVKSLNQYKSIIESKCNDLKFSDFAHLQILNKPTSLYQRSVIFASNWNEFKENSNIIKSSNTKSSNMMLSADIKKIITVFVFCGQSSQYNTMALELYNNNEIFKQSMDLLDCELSKYYGYSVLDKLRSIKDDDIISIHDPTYAQPAICMVQASLVQLYKHWGIEPSFLVGHSLGEVTASYCSGMIDLDTFCYVVYHRSVLQSSTSGCGKMLSISISSDEFISNYSSSYQTIEIACYNSPTSIVVAGNEDQLLNLSKELKEKGIFTAMLGSLSSFHTSSQMMIKDKVLNLNFESKPPSIPSFSTTTSNLYDENTRFTAEHSFQNILNPVYFTQTITNLYNHIESNQLGNEIVFIEIAPHPTLSFYLKQMVPKKSSTTSNYFKDGEFISIYSPLHKKKNDSLEINQLISNLYCQNRYNINFKCQISNDVDFSTAEEPIFYHGLITPPGPSKKLNVFQLPLYQWDDQKYWKSSFIHQNKISNGPPIDHLGIINEYSPNIKSYETYINISRDPLKWLKGHMIKNKYYFPGCGYIDNILKIYPKQDLTIDYLEFKLPLILIDGVNQYLQTNISQTGKKDYKVQFHFKDNKTNQWVNSSNGNIQLLSHDTMNDDNIWIDLESIKNQCNLTKLSKNELYQYIKMKTGLSYTGYFQGVEQVYLGDDCSLSIVSTKQPNENSTSFFHTSILDCCLHGMIGLIDEKCQLIFEKIETLKYYSSNVPTIAKSSNECISVYSKINSRMDNSFSASITVCLMDGTVLLEIENVVCKSLTPVKDSLSIEYPNNELFTPYLQSIESLIPSPLSTQFKPLYKKNETISKQLQVTSNKIFQQFIPRLLLSYINSKHKEITLQLIKSLTIDQLKQKYCTNNIKYERLFVFVFESIKLYIDDCNEDINTTMKLLKNQWNGSNVDNYLFLTKSTRIISKLLFPLVNEDTSIDTPQSLFEDGLMDEFYKHPSLLYQNELVGDIIIECIKPIINEKMVFRILEFGGGTCSLSIPVSERINKLLEEYPSHEIDIEYTWSDVSTSFIPDAKNKLSKIFKNTNISINIIYKALDLEQSLIGSDKLLFASHYDIVIMSNVLHVVKDVKFALKQLYDLLLPNGHLLFTEPIHKSILNDSIFGVFDQWWAFTDTDIRKDRCTMDQDSWRNLLTHFNFQNIEMTIEIPDKSKCYLIQAQKPSLDSIIQISKKSNFTSDHNEKNNLIFYKNSNSNSLENEFIQKTINNTNIKTKIYQVSNIQDFNNLIKSPSGVNNQSIIYFTKSLDLLNSENFKPITLEYIQINQTLLEYKLNGCKHILLSSDSTGINYLASSIIGSFRYFCDFPQLKLYSISLESISKKLNNSFPMVLQYLINDDPIKNTIQKEFIFKNNKVYYERYKQELKLKNSFKSSSFEVGNSTSGINNDSVFAILTQNLEYQLESKQLKLDDNEIEVKIMAGGISYKDYLVYAGLIPPLRTFNRRNDANKPNIGDCFSGIVTRVGGSGGSDIQFKIGDQVYGIGFNTIASHVVVNKKHVYYKPSNITHCEAASIPSVYLTNLYSFFSVGDLDIEMKESILIHSAAGGVGLSALEILKWKGHKGPIFATVGSKEKEKYLLNNYGDIITAVYSSNNRNYSDKIKQKLKEIGWKNQDGVDLILNTLSSEFMDANFKCLTTKGRIVDLSITHLNYNEYTCNNKFKYNKGYHNIELMFVSGSTISKLLKKTTEAIENGKLKLIPIIEFSNSNIKESIEFINKRKYIGKIVINHQDTDIIKELLSKQSSLSNFSILKSNYEINNLGRNIIITGQSGIALEILKWIVTFGSHCVDNIIILSKSSLKWELELLINKTTNLINNKIKFHFKSVDVSNTELMNNAIDEILSIDPSINNIDSILHYAFTQIDCKVNEIDIHHLNVSHGAKTMGAINLHNQSIKREWKLLNFIMASSTASVLGSEDQCSYVSACNVLDNLSKYRISLGLPSICVNYGYIESTGFVAKNDSVAAILVDREGIEPISTNKILGSLDLQIQNQNQSTNLVFCNFNFKNIKNNNNFKFNDQLFLKFDYQINSVISDHNNIVKNDLTDRNSKISDIFLNKISELLSTETSKIYTGGKLLDYGADSLFVVQLKNWIDKNISPNLISIKQLQSNSIDESIQTITTHSICK
The following text describes a protein:
Function:
DNA polymerase II participates in chromosomal DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MSGRRRPAAGGGGGGGGGGGGGGGGNWRRSGSAAAKEQRLRLGAEELLESRLGFAPYTDGERRLGWLLTFSPSSWEDEDTGKIYSCIDLYFVSQDGSTFKVKYKFRPYFYAATKDKMELEVEAYIRRRYEGEISDIEIIEKEDLDLKNHLSGLKRKYLKLQFDTVQQLMRVRNDLLHVVEKNEEKLDAVEAFETIHGVKRVERPQDYINYIIELREYDVPYHVRFAIDKDVRCGQWYNVSVSGSDALLQRREDLLQRAEVHVCAFDIETTKLPLKFPDAEYDTVMMISYMIDGQGYLIINRECVGEDIEDLEYTPKPEFEGHFRVKNVPTELDLLKAWFAHMQEVKPGIYVTYNGDFFDWPFLEKRAAHHGIKMNEEIGFQCDSNQGECRAKFSCHLDCFAWVKRDSYLPQGSQGLKAVTKAKLGYDPLEVNPEDMVRFAMEQPQTMASYSVSDAVATYYLYMTYVHPFIFSLATIIPMSPDEVLRKGSGTLCEMLLMVQAFKANVICPNKHQADLEKFYNNRLLESETYIGGHVECLETGVFRSDLPTKFQLEPSAYEQLIGNLDRDLQYAISVEGKLDIASVTNYDEVKDAIKQKLVSLRDHPIREERPLIYHLDVAAMYPNIILTNRLQPPSIVTDVDCTACDFNRPGKNCLRKLEWVWRGETYTAKKNDYYHIKRQIESELIQSGGIASSKPFLDLSKPEHLLKLKDRLKKYCQKAHKRVVDKPITEVREAGICMRENSFYVDTVRSFRDRRYEYKGLNKTWKGKLAEAKASGNSIKIQEAQDLVVLYDSLQLAHKAGKKLTISYPCVMLNVDVARNNTNDQYQTLKDPVNKLYTTHSECSIEFEVDGPYKAMILPASKEEGILIKKRYAVFNEDGTLAELKGFEIKRRGELKLIKVFQAEVFDKFLHGSTLEECYSAVASVANRWLDLLDNQGIDIADSELLDFISESSTMSKSLVDYGEQKSCAVTTAKRLAEFLGDSMVKDKGLHCQYIVAREPQGTPVSERAVPVAIFETDPEIAKHYLRKWCRISSDANIRSIVDWSYYKQRLSSAIQKIITIPAAMQKISNPVPRVLHPDWLHKKVREKDDRFRQRKLRDIFSPLAKDEGMRSLNGTGDMEDLLMSNKDLRKKSSHGLDIDKENDPNGASVGAGSNNSKNQQNSITGLNVPLSSQIENAAADESIDRSTDYQGWLDAKKRKWKHVREQKKRRRLGAAATFDGPTNALLSSRNVNQLPGNSRNRSTFFQKQELALFRSHWQIIQLDSSTTPGRFFAWVVAEGIMFKIPINVPRVFYLNSKAPVTEEFPGRRVKKILPHGRPCFNLIEVVTTEEQFRAEGKKLAAHLAEPDVEGIYETKIPPELNAVLQIGCVCKVDKSAKKRSIQDGWDLAELQMKTTAECSYLEQTVSFFYLYHSLSEGRAVYVFYFPTSFRIHAVVVNPFRNKEISPSFLEKQFRDACQALGSVPENLTFHVDYQTSIDAGSKYVQRMLLEYRQQHPGPVIGVIECPKLQAIKAAVRALDDFPCVTIPSNARDNNYQALGWQATAGRTSMQRCAASAQWFNERISLARYAHVPLGNFELDWLLFTADVFFSRALRDQQQVLWISDDGIPDLGGTYEGDTCFADEVIQPALTYPGAYRRVSVELKIHHLAVNSLLKSSQVDEMEGGSISSFGSDMPPGPHATETDFDDASLCLPAFQVLKQLIQRCISDAVSSGNVFADAILQHLYRWLCSPRSKLHDPALHRLLHNVMKKVFALLLAEFRKLGANVIFANFSKIIIDTGKVDLASAHAYCDSLLKTLQTRDLFEWIELEPLHFWHSLLFMDQYNYGGIQAKTQNVDSSDDDNDIDIVSSWNIAEYLPKDTQDHFVLIVSEFLYIPWKFMKEQVATQATIRDDTSCTPSITVMAAENLEGQVIGHLRDKISTYFADKLLRTVSDILHHFKGKSKSESDEPASRESDPHTHKGDAALEFIKHICAVLALDQNVQHDILRMRKNLLKLVRVKEFAPEAQFQEPCASFTLPNVICSYCNDCRDLDLCRDSTLQGQEWRCAVPQCGQPYHREQMENALLQVVRQRERLYHLQDLVCLRCRQVKAAHLSEQCSCGGSFRCKEESSYFLSKMRVFLNVAVNQKFQLLQDCVEWILEVR
The following text describes a protein:
Function:
Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Also cleaves PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MEVLGLFRLEVSGPMVTVALSVVFLALLKWYSTSAFSRLEKLGIRHPKPSPFIGNLAFFRQGFWESHMELRKQYGPLSGYYLGRLMFIVISEPDMIEQVLVEKFSNFTNRMATGLEPKPVADSVLFLRDKRWEEVRSVLTVAFSPEKLSELGFSKIQEKIKGHVSAHWVPQRIPLTNFLKPDHGYMNVHNPYHSFCMTPLISRACDVLLAHLERHAQSGEAFDIQRTYCCYTTDVVASVAFGTEVNSQEAPEHPFVEHCRRFFASSIPKPLLVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVQDVRHSAATVGVENFDIVRQVFSATKCPANPPRRHLPRPLSKPLSVDEVVGQAFIFLIAGYEIVTNTLSFATYLLATNPECQEKLLEEVDCFSKEHLAPEYCSLQEGLPYLDMVIKETLRMYPPAFRFTRVAAQDCEVLGQRIPAGAVLETAVGALHYDPEHWPNPENFNPERFTAEAQQRRRPYTYLPFGAGPRSCLGVRLGLLELKLTLLHILRKFRFEACPETQVPLQLESKSALGPKNGVYIRIVSR
The following text describes a protein:
Function:
GTPase-activating protein involved in ER to Golgi trafficking and polarized exocytosis.
Subcellular Localization:
Membrane; Single-pass membrane protein. Cytoplasm.
Sequence:
MAFTEANEREVQSSYEKENVKIIREEEAKDQESTDDIAVEDGTGTSPDLNFFSTQNVMQMNFEDEYSEFSNEDDEAEIDNSFADSIPNEPEIPDMQDEYSRDSHSQQSVEEQNNTTNTDEDASVNEFSVAADISDVNTLGKDNSESTEEPVNEVNETATLGNEDVGERSGFPSEGLDNEPESQRDLDETGNLAPEDLKDEVKSVHEFNEPNDLRQQEESYSDDDDTNVNEFEDVNEIENEHQLSVADEDQTSRLVKGKMIFVGKEDFGEEADISNSVFIEQNGPNSDTVSGFKETSSIVNSSSTTEKPGVALDSQNDTSIFNEEQTNSLTETFNDLTLDHLPENVESEPVAGKENETAKNESGASDNDHKANVHVFVLKSSEDAITLNEEKIATQDDPLEAPTPIVASSSTIFLNSNQRNDELSASGSQEPHPKDGTNSTSSLPLDTNNLSNSEPPSHVLDASSETIEVIQTIKKLQNQVPETIKDEVGKKNTAFSPGTSLSTNHVKTKSRSAHNNSTSPFSTAVSSWLNPLRYPSDKSPRVISSYLESVFISKPRSIGDAQKLEILEYLQSQSSTVSNQVFTLLSNFIQNPLFVLDECFDEFRNLILMHNSHTVHTVVWKTISSWTSYDYEMQYSSLSIKNCDSDKAIRKDLDRTFAPEILSHFFSNRQQLEPTDNIAESTANLHRVLRSLAIVLPQVGYTQGMSWIAGALLMHLPAPQAFALLVFLFKNYHLQNIFSSEMRGLSRVLHQFTRLVEDYMPSLAIHFKRQDIKTCSYASEWFLTLFAYKFPLEVVAHLYDILFLYGPGILFNFGLALLSHSQESLLKLNMDRLISYLKEDIFLAFKETQEGENYDTSLFVKTAFSFEIQPDVLDRYGNEYDILLKSEHELDSSLEEMRNRHKSLNEHFIMLSDSMANLQVEHENMSALLLKEKMYLKNQTVEQASLKSEIASLNSQLAKQKSEIEQAFQGDMEAIIAENLEIMVESQSLEDEIFRKEKQLAETKVNLAVLDEDHMMALQKWSQLMNRIKTK