lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May act as the scaffold of a protein complex, which sequesters key factors that are required for the G2 to M transition in meristematic tissues (By similarity). Together with REC2, REC3 and FMT/CLU, contributes to the establishment of the cellular volume devoted to the chloroplast compartment.
Subcellular Localization:
Nucleus. Cytoplasm, cytosol.
Sequence:
MAPRSSKGKSNNKGKGGDKKKRDDKLLAPSLVEITVTTPYETQVILKGVSTDKIIDVRRLLASHVETCHFTNYSLSHKVKGHKLNDNIQVLSLKPCFLRMIPEEYLEESQALTQVRRVIDIVACTTRFFSKSPNKSIVAGNANPTPAPDGLDMVAIHTTPKLSQFYEFFSIHHLSPPILHLKKVDGEEAGEKRDGDYFGLKVKICNGKVIHVIASVKGFFAVGKQLSHCHSIVDLLQNVSNAFAKAYESLMKAFTDRNKFGNLPFGLRSNTWLVPSPVSESASPLPTEDEHWGGNGGGQGRNGEYDHRPWAAEFSVLATLPCKTEEERVIRDKKAFLLHSQFIDTSVQRAVRAICNVMDTNQQTSGTTDLPAGSILLEDHVGDLSIVVKRDIASLDSKPEATFQNDAFVLSSEELAERNLLKGITADESVIVHDTPALGKVIVRQCGYTAVVNVKGQTQKAMSDFRDILIDDLPDGGANALNLNSLRVEFHRPHSVGTSVENQPTQLDWDDLESYRCIIQELVKINLTKLEETRVSSVRPIRWELGSTWVQHLQKKETDVCGKPATNDETELSVKGLGKQFKDLKSKSKKSENISAVNEKDTRLHELNEEDDLGQKSIDGLFTELKELLSEEAFSRLKETGTGLHLKSKEELTNMAYGYYDEIALPRLVADFGSLELSPVDGRTLTDFMHIRGLQMRSLGHVAKLAEKLPHIQSLCIHEMITRAFKHLLRAVIASVNNMAELPVAVAASLNFMLGRRELEGCDRIPGEEYCLRLQWLQKFLSRKFGWIQKDEFHHLKKFSILRGLCQKVGLELVSRDFDFDSPNPFMSSDIIGLVPVCKHVLCISSDGRTLLESSKLALDKGKLDDAVSYGTKALVKMIAVCGPYHRNTACAYSLLAVVLYHTGDFNQATIYQQKALDINERELGLDHPDTMKSYGDLSVFYYRLQHFELALKYVNRALFLLHFTCGLSHPNTAATYINVAMMEKEVGNDHLALRYLHEALKSNKRLLGADHIQTAASYHAIAVALSFMEAHSLSVQHEQTTLQILTAKLGADDLRTQDAAAWLEYFESRAIEQQEAGRNGIPKPDASIASKGHLSVSDLLDYISSDPDTKGNVAHRKHRRARILQVNDKVASADDDAHRVASQIDIVTWNNVAEADVTKSRSEVNDPDTVVDKTNIETGDIVVHRLNVDRQTVEESTLDEGWQEAYSKGRSGNGAGRKSRQRQPDLMKKRMLLNKHHNRNQDVQQQNIYSPLQKTSKGPSLSKSSPRRALKNAEIDVSTNTTKPQLKASGAAAVTSTTLASKSLSYKEVALAPPGTVLKPMLEKLELNLERTETQIYRTSSASSGEESKSDTVMLDLPIEGTELHCEKQESQESAESVENLTSESEGDLGSYRGKKTSDISRTKLSASAEPYNPGGFLVIDLQSSAATIGSYPIMVADPISWAVVSCGIHSPPYYSAIHSNGVGTPRSMNPDAPEFVPRRSLQNSSQHAGEDASVSVDSSSCLKAEKDAVDLKKRELASFIVKSSQKEVPAALSKTSPEAESGGTSEKDSAVTEIVYSREEENGANANETNGGEGFVIVAKKRRRKNKVRLTNVAAGLYHQPSSVCA
The following text describes a protein:
Function:
May be involved in the turnover of nuclear polyadenylated (pA+) RNA.
Sequence:
MLIENVDAFKTWLAKLLEPICDADPGALANYVIALVKKDKSEMELKAVCADQLDVFLQKETNDFVNKMFDSLQTKVYLPPEETISTDLKQEKEEIKEEIPEKPPVPMPVMETFEEERDNRKKKHPSPPRNRSDSSERRTREKKREDGKWRDYDRHRDKYDWRRGRSKSPVKSKSTNRSRSRSRGRSRERESTRNRGNAKGNSVQQPTSVSLCLSTEHRERQKFESERSELETAYTPCSQLGSSSVEQQYSSGGQAIPSTVTVIAPAPHPESTTEIWSNYYNNHNPPNSFNRNPPPKRRCRDYDERGFCVLGDLCQFDHGNDPLVVDEVSLPTMIPFPPPPGLPPPGILLPPIPGPVHNMRMPVLRPHSQPPPSAVLPAPSLPLPHSGLLNNRDRPVTSTVPSLAPIVGGLPPPIPPPNLLYSVSEHTYEPDGYNPEAPSLTNTGRPGYRTFLQRQPTQRSNLIGLTSCDMDTAPRAANIVIQTEPPASNAGPVNNNRVVVEPDRKRTSSNMDGPFAKKPWMDRQGNHNHNKTGFVKKIQYTNTKLEVRKIPQDLNNITKLNEHFSKFGTIVNIQVAFQGDPEGALIQYLTNDEARRAISSTEAVLNNRFIRVLWHRENNEQQHTQPQHLTPHAASTTQAPIVPAGQGHMQKVMPKAINPGSYVLNKLPAKQPSSGEENQTLPPSTSLSKMVYSSASLKTSNKPAVGSKTVDMQDALKKKQDALKLQQDMRKKKQEMLEKQIECQKMLISRLEKNKSMKAEERTEIMKTLKGLDEKISRVKDELKTLSGPSKVKSKTEAQKELLDAEMDFHKRLSSGEDTTELRKKLSQLQVEAARLGILPPSRGKTLPGQSRGRGRGHGTRGRGSLSHMVVDHRPKTIAVAGFYDNEKEELLQHFAKFGDVEDLKEEEFPPSVILTFRTRQEAETAANQGSKFKGQKLQVSWHKPKTPSISTEIEEEETKEEEAETSDPFLHDDEDEDEEEDDESRSWRR
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The WD repeats are grouped into two tandem seven-bladed beta-propeller regions.
Sequence:
MPFAEKKRRTYENAVKPLRKSRIYAPFRSIGHVSNAVPFDIEARGTHFLVTTSVGNTFQTYDCEKLNLLFVGKQLDKEITCLKSFKDFMLVAAGSKIFAYKRGKIIWDIDVEQEHGTVTHLDAFGEWIIACTSSRHVYVWKHASKYSVPELHTTFLPNTNADITSLLHPSTYLNKILLGFSDGALQIWNLRVSKRVHEFQEFFGDGITSLTQAPVLDVLAVGTISGRIVIFNLKNGSILMEFKQDGQVLSCSFRTDGTPILASSNPIGDLSFWDLSKRRIQNVTYNAHFGSLPKIQFLNGQPILVTAGPDNSLKEWIFDSMDGAPRILRSRNGHYEPPSFVKFYGKSVHFLISAATDRSLRAVSLYQDSQSTELSQGSVISKAKKLNVRPEELKLPEITALSSSNTREKYWDNVLTAHKNDSSARTWNWKSKTLGQHVLPTSDGTSVRSVCVSCCGNFGLIGSSKGVVDVYNMQSGIKRKSFGQSSLSGKPVTAVMLDNVNRILVTASLDGILKFWDFNKGNLIDSLDVGSSITHAIYQHSSDLVAVACDDFGIRIVDVQTRKIVRELWGHSNRLTSFDFSDTGRWLVTASLDGTIRTWDLPTGHLIDSISTPSVCTSLTFAPTGDYLATTHVDQVGISLWTNLSMFKHVSTKALRLDDVVEVSAPSVSGEKGISVVEAALNVESNAEDEEDISYRTMDQLDPNLQTLSKLPRTQWQTLINLEAIKARNAPKEVPKVPEKAPFFLPSLKDQSEATVPKQPIATEISKPTAVASIKVSGTEFSTLLHGNDDDAFFEYLKSLGPAKIDLEIRSLDAYPPYEEFILFINIMTRRLSKRRDFELVQACMSVFTKSHEDVLLMHDTPEDTVPVFESLKAWESVHKEENQRLLDLVGYCSGILSFMRT
The following text describes a protein:
Function:
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
Subcellular Localization:
Cytoplasm.
Domain:
The PRC barrel domain binds ribosomal protein uS19.
Sequence:
MVSMLLVGRIGKSVGLNGGLRLHLESDFPECLKKGVKVSVAPLNAFSCVSSFKEYIIHSYEHAKNLLFLETIQTPEKAKELTNLGLFMSEAESKKLCVLKEGEFFYCDLVGLSVVEENEILGKVIEIQRISQTDYFLVETTLNLVEKGLAKIFLIPYRDFYIQEILLQDKKITTHNAKTLLENS
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MADAWQGSWRWAVATTNRGGGDPVQLRQPPPQPALLHHHIYDDNCGASSTASGTILSMSNTTTYAPSTAASLPFPFTVATAGGLTDEEKKATMREHIRDLIIHGSRGGAAAAGSSSALGRWLSELQVSWVLHVAQLDAASAGRTFVSRRLQHTARSWVTAIHAIGRCVASFTGWCSSQEQQEEEQALPWPPASELVGFVAATFLLMLPFVDAVVALDDVVGPVSASSDDDYGHGGVISGNKGAVASAHKFRTLTDVRDALAGVSEQVQLWHSCLSSSSCSSSTDAEAARMSGEMRSLLLAKLDKVDEAMRNTRDCIRTHFMSLMTDGHGHDHDYKAASGLHPSPGIHVATQFAARYIIVLSTSYYSYNCSSVDPPTAYEASLCLGENNTSSSTNLNIVIIRSLEESLTRVSQSFPDQSLRFLFMANNFYFLWHQLLSQNLLLDVPTDVLAHKIDSYINSYLQVSWTPVLKPLHSHSSPCCFFFMRYSAQHKFLSEFEKAYVEQKLWKVPDPELRKLVLLLRPSFHCGFK
The following text describes a protein:
Function:
Exolysin that catalyzes the cleavage of the host peptidoglycans during virus entry.
Subcellular Localization:
Virion.
Domain:
The C-terminus contains the peptidoglycan hydrolase activity.
Sequence:
MAKKVTLPKGQTGATGTTLGQAGNILDLSDVDDIFGDTPKAKKGSPVTEFFNGIKQGLFDSVKPQQALKAFMRSAAPDGFSRMFGVYEDTMSTIRDVKDSVERTSASDLLFLTREAQDLAVKLKDKVPASVFDRLNNRLESQIENYKYAEDSNRNYKEIRRRMEAERDEDELKSAIDQVTLVQRDLAIKAEQGEVKRFAIGQAERGIRDKVSADRFDWMAKAMGQTVDNLSKLASYNEQVNYSIQKKGLEIQFRSMLHLRKIAQQTEATMELLNNGFAALVRNTGIPDHKKSSMKDLVGFNAAQRVSSSFVDNAIQTLPNFLGNFGSAVTNNATRFANENIRNFADAVRAGNMFGADAWENRYNIAGQFAGSYLGDWTRNSVIPVLGRMARPGIERFSNNYLGGRHNQASYLLDNFPAWTQEYMNNYQNTYGARGILRDIMAPFIPQFTLQDRLKTGSYQTIGQDSGFNQLTQRTIVEAIPGYLSRLLQETRMIRTGRDDITREVFDLSTGSFMSVEDSAANTERRLVSRSTVRGVSGALTDVLEAFDPNKELSIDARKALTERLIRDANMNKRFDPEAYARAGGYDRSKVSGETIKELTEYIKRQYNIGADGRMASTNENFARRQEISTLFLDVRNFSRDPIKEIERLTNAGKTDQLREMGIIITEQGIDRINYPRIWELMSSEVKYEGWGNDNPFDRYSDTPPSDNGGPEQLSPLGDQNNPHFIGPMYQSQTERKMRQAQEQVIRASKLAQEQANKGYDYAQQKVSLATDYVRDNVPNQFSELRRNVNIPASMNFGDLRDQLYGQAGDMYSRAVNYSNQLNGYSDIINQSIADLYTKANTFTPVIKGMDFLNGNLIDINTGMIVEKISDITGEIKNQAGITVVTAQEVATGLYNQRGDLLTKATDIASQLRDKAAQIAGDARERLTQGLDNVSDMAKDWYIPGREEAVILGRDLLAGEYIDTATNQIITNLKDAKGTIINRAGDVVVTAQELAKGLIRSDGFNLRRNIADTSNWIQRNVLGGGSTTQKIFNAMGTVANKAKDFTIGLGKDILSNRDAYLPGMLKPVLQKVKLKAGEYYTTAGNLLKSFDEINGPVLDRDGNIVVDEEQISELINSDGSKHTAAKSKGLFRTGLGNLARGYANMSMRYWKWLGKKSVDTAKGMAGLGYKLLGSPFKKRFSAFTGKVETQIDKKALDTTTDQLLAGIWEELRNQKPDANKPRRGSWQDLTSRVSDTLNGKNNGDEETTESKGLFGKLGDTLKNIFGKKKGDEEDEGLLEDLGLGGKKGGKWAAARQILGRGALAIGGGALSTAAAYASFGGTGASTNDKLAGAAIVTSNPIMWALKDFLIKPVLGWRGSQKFKDDLISYRMMQYGATTTDQMNKVTELEQLVSSVATRGGDASFDVRALNARDIIKIFGYGADDGPAIMRLANWIDFRFKPIFEAWLKGLSKINRSDVDISEVDSKVPNELKGQLIRSVSFPYEGNTPYLVLNNPFGEEDLSIDVASIQMKEKELLNKYSATEKTSVAPKATSSSFKESTTDVINDTITTIKSKSTDITNWFRDSTIGKAIKAVSPVESIRKMVTTTVDTIIPKANASDSLTSLQALRVHAYGMQGLDLAAVNGLLSIESLVNDKMRVANGKATYTGDIEELIKWTGQAFGMVTTSDGPDRVKVVDWLYRRFLPVFKAFIVTARSVSTSITLSQIETLTATQRVQIANAIMGATDDEGISIWKAPSIFNIVGDMDSVEDLAKISLDEIKKEAETEVAEAPGKSKSAQIAGKNDAASGRSFASRIIDNVKSTFNSATTKVTNWMENTSARVSQVIGRAREGVTDTYYTAKYKLGAGGELTPTGQTYGQLATGNGGVWENIPMPQSNKSRDAAQATFKAVSEMTGVPVELLNIFCGIESSFNYNAKAPTSSAAGWFQFIKSTWKGMLAKYGAKFGIPADDENGSLRFDPRINALMGAMFLRDNYEYLENALGRAPTDVDLYLAHFMGPAGARKFLTRDQNSIGAEIFPDQARANRSIFFKTDGSARTLGEIYQVMENKVAKFRTGGGKNANSQSLGKPKSTEELMNDAATAKQKDMATDKELIGGAADTSITDSSNNKIGLGKIMSGMASPLRTNAPSMMLPGAPSSATDVSSGQQPVVDTGAATQATVRASQIEEQRKVVTSQDKAMLDIASEQLSVLKQFHADILNYIKNKAANPSAQTGQEQANTIAPSQRPGRVVDNRPLPIRLR
The following text describes a protein:
Function:
Component of the transition zone in primary cilia. Required for ciliogenesis.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes the transition zone.
Sequence:
MPPTSRPVPPPPKRRISESSSSSDDELTGNNSFRENQQRRFRENNEVGNISDSDNDEVFSHQESQSVGFIETDEERQREEHAQNSNLRNRRVSYGKIPVPPMSMTVEDIQEAAKHSREDPSGETVEVRRPNDPRRSSVSLDVFKSFRDPHDKRNMPAKDKTIYVEGPNGKFREMKKGKFWNRDKFDSPKKDAEKKQDEDSVIPFLLKAPGQAYRTQRVYNQIANIIQGFLAGISVMLAIFSFNLEPEVLLTGYRYMSLPIHAGFMVAFTVGLVSAIDRTGIYEVEHFTSRTRLTATVYNNGLITFIVWFVGLVSTLLCIQLESQLAFAPTRIPSEDLVHHWRVFNVLRALTSGLGFLLLAFKPDSDTMAKELREAIYEQLELVTSDPERRRVIITAMKI
The following text describes a protein:
Function:
Involved in the regulation of the TOR signaling pathway. Seems to act as a regulator of PP2A catalytic activity.
Sequence:
MGSLKMEDMSLPTLFEQARKIHLLATDSAADKEVLRKGCEALQQCEEMISKLGLFSTNETKEDISTTNLKYILVPFYLAELTEKTGEEDRIEILKVAQAKSKEFLSFCDAMELVPEDELETSEQGGQNSFVDRRAKKIARFKRQRAAESKLLELKERKERRGRSTKAAAPLSTPADVNDVLDDDDDGEEEREAWLTTISLAICKALDLMEMLKKEEEMLSAIKEKKEQEGGIEISEAILEERAKTVEDWHRNAAARARYMKPAAPITCATFAQDVLEGRAKVSQPHDHKHQQPLLFGPASLVGPGGGTSHRERIAAQVFQPGHRMPTMSIEEAGLKEMDMMNKWQERTAKMIEEANTSWHNDKWKPRAGGGEDDEDEDEDRTRAFDDWKDENPRGAGNSKLTPCG
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MPRLPVVCLLPRRRVTLLVLQPGQRLAHSEPPRQRPVSTLEVAIALVVFFTAFLTPSGYVLSNLNQFRRE
The following text describes a protein:
Function:
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRHEIEAETDRVTGMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIEHEVEGYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKNTIGNQGTNLPPSRQIVIRKGWLTISNIGIMKGGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLELACDSQEDVDSWKASLLRAGVYPDKSLTENDENGQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALVIIGDINTATTFTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLPRPASGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSSSGSGSSDWFGAPPQVPSRPTRAPPSVPSRRPPPSPTRPTIIRPLESSLLD
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MQRTASKGTVQSPVCLVQGRARIVDDAAPLHYVGHWDGLGRATLSNNGQSAVLTLSERPFRPFLVGGPLGSAYLFEQLHFHWGPDDAVGSEHLLDGRAHSMEAHLVHYNARYGSFGAALAHPDGLAVVALWLDGGGSAVWRPLQPIVRALRHIRRPGTRTTALPADCLRWLAAGLELGRHYYTYDGSMTTAPYRECVRWLIYRTPVYVSPRQTAAFRRLLGRCPARPGGDRFAPITSNFRPVQRSAAGGDPLGLVFVRDSVGAARRAKL
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor contributes to oxidative stress resistance.
Miscellaneous:
MISCELLANEOUS: The interaction between YlaC and YlaD may be regulated by the redox state of YlaD.
Sequence:
MKHRDSIEDLYRQYYQEILNYLFRRTHHLETAKDLAQDTFVKALNGLASFRGHSSIRTWLYTIAHHTFINWYRRDVKYQFTEISKNEGLTQTTYDQPEQYLSRTVKSETLRQELLKLKDQHQSVLILREFQELSYEEIAEILGWSLSKVNTTLHRARLELKKNMTKSREEERI
The following text describes a protein:
Function:
Core component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Can mediate Pol I proofreading of the nascent RNA transcript. Anchors into the Pol I active site to monitor transcription fidelity and cleave mis-incorporated 5'-ribonucleotides.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPRASPSRKAGAALPETTSPRMPCARLLAGRICSTAPPLEPLAHQSWERERGAEHRSPAFGGAASPKSPFLRPRSRWANRKGRGGVGDLLASPNPASFTMTAVTTSASSFLSDLDFCPECGSILPLPGAQDTVTCVRCAFAIDVRDFEGKLVETTVIFNKLGATAPLAKEEEAPETRGPVVDRRCPRCGHEGMAYHTRQMRSADEGQTVFYTCTRCRFQEKEDS
The following text describes a protein:
Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MNWAFLQGLLSGVNKYSTVLGRVWLSVVLIFRVLVYVVAAEEVWDDEQKDFDCNTRQPGCANVCYDHVFPISHVRLWALQLILVTCPSLLVVMHVAYREERERRHRMKHGPQARPLYGNPGKKRGGLWWTYLLSLIFKAGVDATFLYIFHRLYNNYDMPRVVHCSVDPCPNVVDCFISRPTEKKVFSYFMVATAVICILLNLGEVSYLICKRAQELLGPQNSKQPRRHHRRHGHHGPLGTLQDACPPYAPAQALSQGDPTKEATLPC
The following text describes a protein:
Function:
Ketoamine kinase that phosphorylates ketoamines, such as erythruloselysine and ribuloselysine, on the third carbon of the sugar moiety to generate ketoamine 3-phosphate. Has higher activity on free lysine (erythruloselysine and ribuloselysine), than on ribuloselysine and erythruloselysine residues on glycated proteins.
Sequence:
MNEQWLEHLPLKDIKEISPVSGGDVNEAYRVETDTDTFFLLVQRGRKESFYAAEIAGLNEFERAGITAPRVIASGEVNGDAYLVMTYLEEGASGSQRQLGQLVAQLHSQQQEEGKFGFSLPYEGGDISFDNHWQDDWCTIFVDKRLDHLKDELLNRGLWDANDIKVYDKVRRQIVAELEKHQSKPSLLHGDLWGGNYMFLQDGRPALFDPAPLYGDREFDIGITTVFGGFTSEFYDAYNKHYPLAKGASYRLEFYRLYLLMVHLLKFGEMYRDSVAHSMDKILQDTTS
The following text describes a protein:
Function:
Catalyzes the activation of 2-hydroxy-7-methoxy-5-methyl-1-naphthoate in the biosynthesis of the naphthoate moiety of the neocarzinostatin chromophore. Also catalyzes the activation of other 1-naphthoic acid analogs such as 2-hydroxy-5-methyl-1-naphthoate or 2,7-dihydroxy-5-methyl-1-naphthoate in vitro.
Sequence:
MHETAAAPAPAGFVPWPDDVAARYTAAGHWEGRSLGTHLAEAARKVPEAVCLVDGPVRMSYSELMARADGAAVRMRGLGIRPADRVVVQLPNCWEHVVVTMACLRLGALPIWALPQYRHRELSGVVTHARASALVVPDVYREFDHQALAHEVAEAQPTVRHVLVAGSDVRPDSVDLRALCEPLDADEAARVAAELDRSAPRGEEVAMLKLSGGTTGLPKLVARTHNDLSYMIKRAAQVCGFGRDTVYLAVLPLGHGFPNTGPGVLGTLLAGGRVVISGSPAPEAAFALMERERVTATSVVPAIVMRWLQYRDERPGADLGSLELMQVGASRLEPEVARQVGPKLGCRLQQVFGMAEGLLCLTRLDDPDDVVHYTQGRPISPDDEIRVVDPEGRTVGVGEPGALLTRGPYTPRGYYDSPSANARAFTPDGWYRTGDLVRRTPDGNLIVVGREKDLINRGGEKINAEEVEGFAVQVDGVLQAAAVGLPDSELGERICLFVVLADGTRVELADVRKVMENAETASFKLPERLITLPSLPTTPMGKIDKKALRAAAGRMSET
The following text describes a protein:
Function:
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix. Cytoplasm. Secreted. Note=Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Sequence:
MACGLVASNLNLKPGECLKVRGELAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDDGTWGTEQRETAFPFQPGSITEVCITFDQADLTIKLPDGHEFKFPNRLNMEAINYMAADGDFKIKCVAFE
The following text describes a protein:
Function:
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.
Sequence:
MVTGSEEYSPPRTGAPPTYEEAMGLFADIPPPPFDMLRIQEQLPGAVTTQPSVDSEDDIKWMPLPRIDPGSSCPYGLEYLLELNTVLVKRERWRMFEGRRYGVSNSLGEKFLAFGKCLSGRIRIIQVYIASDTGTFCYSVQDHLERHAFTIKRESYCMCYGMASECAVECPPGQPSGFIIGSAGLCMSNIVITDGGKSCIFNINAPIGRGLCEDENMPVCEIVGNVLASSSCLVLSNRVPVANIRRRYPDVPLSERFDYIVTFPIDLEVRMKAALIATAVKIDVEIAEQRTRSNN
The following text describes a protein:
Function:
Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (By similarity). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Domain:
Binds to actin monomers via the WH2 domain; The Spir-box targets binding to intracellular membrane structures.
Sequence:
MARSADRSAEDGDSRAGIRELSLEEVLKSYEQPINEEQAWAVCFQCCGDLRAPRPQPHPRRPELQIRDPASIILHRDGRVTALLQSCDDSNAGCESAADGKLVQSLGVAIYRALDWGLDDSEERELSPQLEQLIEFMVGGPDCGQSKHCGSNAAKDEGYSGQDEEEEEEEEEEEEGAGRGIHTVQQVMTMCASRLANPVLAPEHYQAVCRALFLETLELQTFLSRIRDAKEMLKKIRKEEPQEDSAAELDALQHTDWARLWVQLMKELRQGVKLKKVEEQPFNPLPTEFSLTPFEMLMQDIRLRKYKLRKVVVDGNIPTCVKRNAHELILDFIRSRPPLKPVSERSLPPPPQRPQSLHDRVLAEIRQDHKLRPVELPSSKRSFGSLPCLAHTCQCDIKSTSCIDLSVTGAGSRPSSRIRVLLKAPTLAEMEEMNIFEDEDSPDGVDMRRVESSPTPLKRDRSFSEHDLDELRGEMMSDSPQHSGVAALRAERPRSHTLTGVYQASFPGFERRSASTCRSLSSDDRSSDPGGDSASHGLSRHQWMEEFCHPVETLALTVDGVINVRRILVKAEMEKYMQNKELFSNLKKGKVCVSLSYMIDISPTAQ
The following text describes a protein:
Function:
GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence.
Miscellaneous:
MISCELLANEOUS: IFF11 differs from other HYR1/IFF family members in lacking a GPI-anchor.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MLLSNLVIPLLATSATVSATFDVTSSLTKYAAFDFGVGDISIQKSASFSLINTFDCAFQGDINIEKDCEFLIASTAKALKLTFNNIFHKIENKGKWIVHTLESAAASTCNIIVKSFVNTGEIILAFKGHVLAPIINIAASHWVNHGCLHLFQEIKSISVAILGVVGGTIENHGTICLTNQLCKQVTKIIGSGCIALEKSSSFFISNSFLSIDAQHTFYLGEGNPTIQAQAVSLPQTFKVANFGANGSHKIGLNLPLLSITIAGKKGWSYDTKTGILTLTANGFISQKFDIGLGYDPSKFEVCTDNSVGIVSVIKGSIKYNGPCPHAGRPSVCQICPGVPTPPVITSSATAITSTQSKTTSSSSTSSIATTSTTSSKPKPTTVSTSSIASTTTPDGSYSTSFVTVTAETTKVVTITSCSNNACHPTTAPTGLTVVTLTTSDVKTVVTTYCPLTQTVTLGVTGTKTVDLGCPTGYFGYNGYIGKGVSIGHGGAAASASAGFQIGFDIFKNHHF
The following text describes a protein:
Function:
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
Subcellular Localization:
Nucleus.
Sequence:
MATDACQKYIKDGKLTLSTGCINTSFIELNEASENAKIIQIINYKEDKNKKVGAFKAKIIDGAFAFHPVFFHESLAEQLVKDGIVNGAVNSENSPIIATYSLCPSNMAMESNRLPLMIKSYELLYTNCPALESEKSNLIKYSGDPEDHKGFDKTKITPVFIAVNGGVKTEKTEAPPTTISNPSIPIKVVAPLINKPIGMATRGAPPPMKTNSSGSSNQSFTPISAITPYASKWRIKGVVTSKEEMRTVKMKSGESKVFNFDVCDDKNSTIKCVAFGDVAERTYLVVQENQMLAISGCGVRQANKRFNNTGHEYELSINATSEVAPLKDGPVIVVQYELKNRVKLDELPRKVGESVDVLACIDKVNELNAFTSKNGGNFVKREVSLIDQTGVNINFVLWGDQAKNFPEHTEGQPLGIKGVFVKEFNGGLTLGTTGSTKYVLTPDVDGMAEMCEWYNNSRGTVQTQSLSTGNASEGSLGRDLRLLGTASALQLGRGEQVYMNVKGRIMSVKGETAIYKSCPSENCSKKVIENEDGYRCDKCNISGDKYKFTYMLQMEIADMTGQIWITMFGKNAEQFMGMTAEELAEIKNENPSEYEDIFHRLKFATRIFRIRAKSEVYNDEERIKYNAFTVDVPDYNKLNPILDTVIDRLNALPI
The following text describes a protein:
Function:
Required for nuclear membrane fusion during karyogamy.
Subcellular Localization:
Endoplasmic reticulum membrane. Nucleus membrane.
Sequence:
MPDENRTLMEDSADLGLSQDEFVRMLGDHPSLRRSVTRSECHSHIAARLPLSCGSEEHEGQVSESNRRAIAISFTLCSMQSALQPVPNECLPWWQLSEPPVKKPSRIMSVWSNTPPGESDRQALCLGAIHRSPQDWNSYNTFLSDATQLCHVLQGQQEIAQARELYANATMEKIALLKYLKKKDQDRLQRELKLEEYIEHQSTELQATSRELKTASCKMQLAIDQYELLSTALDQSIQSLATGRERLWENVQENIQYETTLAGQLFTKELHQLQDMLSKKLTAQLGMITDQYGVALNAQAEAADSLVKSLQYQMQNYLSDLTTQQTAQMSTLQHSWEILTYQTSRLVGDLQNLETGAKALQGVLEQSHDIAISTKISQELAATWLQAGVEQAERISTSLNETEGRMDLVLTSLEARQQQLDQSWRWSPSLFASPALISLGQGKSDFAAISCRGLLVVLDICWQVICYMVSATACLFVVSRAGMKKLFAPVLDQAVGDRLQDKERDIKVEKPTGFSLSFPHTPERLPSYHSVYGSHISPTACPRHLPGDDHPIAGRARTIADEWVERGRRSCTAPL
The following text describes a protein:
Function:
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
Sequence:
MQEGRMSSYTVKVEESRPAADGKPSAGPVYRSIYAKHGLMEMPTRFDFESPWNFFSESVKKNPKYQMLGRRQVVDKKAGPYNWLTYEEVYETTVKIGSAIRSRGVNPGDRCSIYGVNCPEWIMAMEGCNSQAISYVPLYDSLGANAMEFIINHAEVSIAFAQESKIPAILSCLSKCHSYLKTIVSFGIISSSQKSEAEEQGVACFSWEEFVQMGRLDHELPQKRKTDICSIMYTSGTTGEPKGVILTNDVFMGKVLSLDHLLAETDKEGTEEDVYFSFLPLAHIFDQIIETYCIYRGASIGFWQGDVRYLIEDLLVLKPTIFCGVPRVYDRIYTGVMDKIEAEGALKKLLFHYAYNYKLRNMEKGLRQDEAAPRFDRLVFNKIKLAFGGRVRLMFSGAAPLPKHVEEFLRVTCCSSLTQGYGLTESCGGSFTSIANVYSMTGTVGVPMTTIEARLESVPEMGYDALASVPRGEICLRGTTLFSGYHKREDLTKSVLVDGWLHTGDIGEWQPDGAMKIIDRKKNIFKLSQGEYVAVEIIEGVYSRCPLVTSIWIYGNSFESFLVAVVVPERKALEDWASSNQQTGDFSSLCNNAKARKYILDELNSTARKHQLRGFEMLGAVHLEPNPFDIERELVTPTFKLRRPQLLNIYKWDNLYLSSQLFQLSKKVNSQSIASKAADSKFSAEVESILGVTFGSLGAVTRSKAGLLGQQTHPVSSGPAPVFGSSTPKGTKSNEIALEGGSSVAESLKKTLALLKHSGSKYFGAKDDDRSSNSSSPNTQHKLSTSKVNLRNNPCYSPTSLVIIQVMMTDASLMEEQLTNLTKAIEGLTQYVQNQDVRIDKIVNRVEVLIDRESSHALGKTPEVHEIENPVKQTPPTKKVQVSSEGMIPIGQLREFIEGTLKDKYDVGTKSSLAYAKPYTARIDSLKMPAGNQPPKFQQFKGKGNPK
The following text describes a protein:
Function:
Mediates the association of the molecular chaperones HSP70 and HSP90 (By similarity). Mediates nuclear encoded chloroplast preproteins binding to HSP90 prior to chloroplastic sorting.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The tetratricopeptide repeat (TPR) domain, forming a carboxylate clamp (CC), mediates interaction with the highly conserved 'EEVD' motif at the C-terminal ends of HSP90 and HSP70.
Sequence:
MADEAKAKGNAAFSAGRFEEAAGHFSDAIALAPANHVLYSNRSAALASIHRYSDALADAEKTVELKPDWAKGYSRLGAAHLGLGDAASAAAAYEKGLALDPSNEGLKAGLADAKKAAAAPPRRAPSGGADAIGQMFQGPELWTKIASDPATRAYLDQPDFMQMLREVQRNPSSLNTYLSDPRMMQVLSLMLNIKIQTPQDSDFSQSSSPSQPPPQQQKQQPETKAREMEPEPQPEPMEVSDEEKERKERKAAALKEKEAGNASYKKKDFETAIQHYTKALELDDEDISYLTNRAAVYIEMGKYDECIEDCDKAVERGRELRADFKMVARALTRKGTALAKLAKNSKDYDIAIETFQKALTEHRNPDTLKRLNEAEKAKKDLEQQEYYDPKLADEEREKGNEMFKQQKYPEAIKHYNEAIRRNPKDARVYSNRAACYTKLGAMPEGLKDAEKCIELDPTFTKGYTRKGAVQFFMKEYEKAMETYQAGLKYDPNNQELLDGIRRCVEQINKANRGDISQEDLQEKQSKAMQDPEIQNILTDPIMRQVLMDFQENPRAAQDHLKDPGVAQKIQKLINAGIVQTR