lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Bacteriocin with antibacterial activity against many strains of L.monocytogenes, L.seeligeri, L.welshimeri, L.grayi, L.murayi, L.ivanovii, L.innocus, C.divergens and C.piscocola. No antibacterial activity was detected against L.lactis, P.acidilactici, P.pentosaceus, L.salivarius, L.delbruekii, L.acidophilus, L.plantarum, L.casei, L.rhamnosus, S.thermophilus, P.freudenreichii, B.breve and E.coli.
Subcellular Localization:
Secreted.
Sequence:
TKYYGNGVYCNSKKCWVDWGTAQGCIDVVIGQLGGGIPGKGKC
The following text describes a protein:
Function:
May function as a nuclear transport receptor.
Subcellular Localization:
Cytoplasm. Nucleus. Nucleus, nuclear pore complex.
Sequence:
MALHFQSLAELEVLCTHLYVGTDLTERIEAEKALLELIDSPECLSKCQLLLEQGTTSYAQLLAATCLSKLVTRINPLPIEQRIDIRNYILNYVASQPKLAPFVIQALIQVIAKLTKLGWFEVQKDEFVFREIIADVKKFLQGTVEHCIIGVIILCELTQEMNLVDYSRPSAKHRKIATSFRDTSLKDILVLACSLLKQVLAKPLNLQDQDQQSLVMQVLKLVLSCLNFDFLGSSADESADDLCTVQIPTTWRTIFLEPETLDLFFNLYHSLPPLLSQLALSCLVQFASTRRSLFSSPERAKYLGNLIKGVKRILENPQGLSDPGNYHEFCRFLARLKTNYQLGELVLVKEYAEVIGLIANFTITSLQHWEFAPNSVHYLLTLWQRMVASVPFVKSAEPHLLDTYAPEITKAFITSRLESVAIVVRDNLEDPLDDTATVFQQLEQLCTVSRCEYEKTCTLLVQLFDQNAQNYQKLLHAAPGLAVDMAIQEGRLAWLIYLVGTVVGGRLTYTSTDEHDAMDGELSCRVFQLISLMDTRLPHCTNEKIELAVLWFLDQFRKTYVGDQLQRTSKVYARMSEVLGITDDNHVLETFMTKIVTNLKYWGRCEPVISRTLQFLSDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISETYNVGDFRCRTTFYTALTRLLMVDLGEDEDEFENFMLPLTVSFETVLQIFNNNFKQEEVKRMLIGLARDLRGIAFALNTKTSYTMLFDWIYPAYLPVLQRAIERWYGEPACTTPILKLLAELMQNRSQRLNFDVSSPNGILLFREASKMICTYGNQILSLGSLSKDKIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFVKMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFITNLEPPVLLYVLTSLSEGLTTLDTVVSSSCCTSLDYMVTYLFKHIAKEGKKPLRSREAMQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLGQCFRNLMEGVEQNLSVKNRDRFTQNLSVFRRDVAEALRSDGHTDLSSLDMMS
The following text describes a protein:
Function:
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
Subcellular Localization:
Cytoplasm.
Sequence:
MDQAIAKADTLIEAMGWIRRFRGKTTVIKLGGSLLEDREALQHLLLDVIFMETVGLRPVVVHGGGKAITEAMAKAGIEAQFIRGRRVTDEKSLEVVEQVLAGELNVELTEMMERFGGRAVNLSPRTTCVLKGKKLIDPEGDDLGFVGEVTEVDRDVIESLAYTDQVAVIPSLCTDDKGQLYNVNADTAAMAVAQSLGADKLVFLSDVNGVRRDPEDPATIIPALSAEEARQLIADGVIKSGMIPKVEACLETLGRGVQKVHIIDGRLRHSLLLEIFTTDGVGTEIHQ
The following text describes a protein:
Function:
Promotes the exchange of Ras-bound GDP by GTP.
Sequence:
MEPTINPPVNLPPPVPSRSNLSLNYSNNNTNNTNNTNNTNDFKKKLQFQLQSSPSSPSSPSPSIIYKKTPAVNNNNNNNNNNNHINNGNVNGIGPGGGNSYISSPQSSPIHTSSNGISYTVTTNSPPLLPVDNSSGYNNNLNSTFVETLSSSSPSPIKTTTTPPPPVPSKSKSKSSEKLSVKLLKSNSKPSLNDLYQQQQQQSNPNSPTTPPSNCNIESIQPPSSSSSSTTPSTSPQLPAIYSKYSKISLPQLPLPPFLPPSPLVQSTSSPSFSSLILPLPSSPLPPPPLTIPNKVPPLPMRLPPPPPPQQLDQMYSNNNQQQQQQQQQQQNNESNSTTTSEGGLTPESESKLYEIASQPPSTPRLTHESKVIPSEIELLIKFYPSPSLSSGSLLTIPSTIEKSFIFSPCSTVDEILSIIIPNFQFHNGLKCFAKHTFNNEWEATHNDPAAASSSIIDDHESFALFNQKSPTIPLHKEKTILELSLHDRDVLILKTVSLVFTLVKVQIPHFTENSLSATATVKFNQFTSIRSIIRKLYLKYHNNVDISRHGIFLINDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNLHQQQDELSSSIQLEEEELFSTYNINSNSNLVFRTISNQENDILNSSQKILNLKILISSTFSRNNTLNLMFDPRDSVSKAIKVTGLRTGLLDSLNKCGFYLTPSEDDDEGFWMDEELTLEMYNLKNHTFLSFKERCKKYTILIKMGGASNGNGNGDLTWRKCTFKFDQFTKVSTLFNILINNENIKNPKDYHLVVKSTGTSLEKHRYLWSYDIKSPYEIEFKEYPNKLLIFNPQNGEKNFVYVDFNEPIKDVCARLSQTFSSPIDFGSISTNNNNNNNNNNNINSNSNGSSGAGGANSNALTSSTNSASTTSSSTPTTPELPPQVNHVRERSYTFKRLGQLNNTIDSRKSLKDQGVLPNDALMLEVIQDDSIATNNNNNNNNNNSNTTTTIKDKKINRNSLPSSTTMVFEDLVKDGTILSEERQINIWDEPADSNGNIIYSKTVTNNLNAEIDAATLNKLIIRLTNPVFHDLTFMKTFLMTYSSYTTTTTLLKKLFERFQVPTHIDERERLSAQLRVANVIKYWVEHHYEDFCHESTKLMVDFVDTHMMIAFPTLGVQIRNCILKRTCGFKSELVRTRSNGALTSPRTNLSLSFTNLNNSSVGSIANTSSSTSTSSTSSLLSSTNSISISSSLSLSFNSGINSPSISQNTPSSPSLIPSSPRPITSSSSVSSSTLLKSPLSQQAKSRIPETKTKGFANPRNLFDFDDEEIARQLTLYDFQLYTAIKPTEFLNQAWNKPSMASRKSPTILKIISRFNDISLWVVSLILEPDRVKTRAKRLKRIISIADELRKLNNYNTCIAVISGINNSAILRLKYTRGLLSKKYLDILENLEKEMSCEGSYKNYRDKLKNSDPPVVPYIGVYLTDLTFIEEGNPNIIRGNLINFAKYYLIYRVISEIQQYQWTEYQLNVAPIIQTFIRDVSISSTSDDLYHLSLLKEPRNALKSDIF
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Sequence:
QRFVQGPTPLREEAETRARPQLPAPAQGSFPPPLTGSDGRSRCFPSCPLRDPRWGRGACWRAAGNLARAGIRKDTVASERAGIGGCCLRAPGSGGLCFRGEGLPRRTRGAAVSAPGARGGRAGWRRGLEVGDREGRPRAAVAAGFRDGACGSHQPCLSSASGGRALGVQRGKSRIALPGGDCGLGVQEWILLICEMQLTHQLDLFPECRVTLLLFKDVKNAGDLRKKAMEGAIDGSLINPTMIVDPFQILVAANKAVHLYKLGKMKTRTLSTEIIFNLSPNNNISEALKRFGISANDTSILVVYIEEGEKQINQEYLIAQVEGLQVSLENLPEVTNITEVRKIYKLSSQEESIGTLLDGIVCRMSTKDVL
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Sequence:
MATPAALELVAVTKRYDTTLAVDDVNLKIPAGTYCCLLGPSGCGKTSTLRMIAGHEAVSEGDIILGAQNVTDLEPAKRGTAMMFQSYALFPHLTVLDNVAFALKMRGIDRATRHKRAGELLELVAMTPYAARLPAQLSGGQQQRVALARALITEPQILLLDEPLSALDPFLRVKMRGELKRLQRELGISFIQVTHGQEEAMALADHIVVMNHGKIEQQGTARDIFHHPRTEFVARFIGGHNVLSDAGRLIAVRADQLGIVPFADGAYGAPALLTQTEYQGSYIAVSLTLDDGTALFSHLPEAAFDVHPFRPGDRVLATWDPAKAQRLQ
The following text describes a protein:
Function:
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Subcellular Localization:
Cytoplasm.
Sequence:
MEMSLNPVRVLKNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGELKSIQIIKKSGGTLGDSFLDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCTGGEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEACTIVIRGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIRCAPRRRVPDRGYC
The following text describes a protein:
Function:
Organic zwitterion/cation transporter with apparent specificity for amino acids and their derivatives. Substrate selectivity and the transport mechanism, symport with sodium or facilitated diffusion allosterically regulated by sodium, remain to be elucidated.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEVEEAFQAVGEMGLYQMYLCFLLAVLLQLYVATEAILIALIGATPAYHWDMADLLPNQSHSNQTLGKGQAFGDWLLTANGSEIHKHVHFSNSFTSIASEWFLIANRSYKVSAASSSFFSGVFVGVISFGQLSDRFGRRKVYLTGFALDILFAVANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAVLVNLQGTLVFLLSLFIPESPRWLYSQGRLSEAEEALYFIAKRNRKLKCTFSLTHPANRSYRATGSFLDLFRYRILLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQRWFGRKRTLAAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGACSMFSRVGGIIAPFVPSLKEVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQMYSYRRLGEEALSLQTLDPPQPLDKVSSESEEEEEFYDADEETQMIK
The following text describes a protein:
Function:
Responsible for the aerobic transport of succinate from the periplasm to the cytoplasm at acidic pH. Can transport other C4-dicarboxylic acids such as aspartate and fumarate. May also play a role in the regulation of C4-dicarboxylic acid metabolism at pH 7, via regulation of expression and/or activity of DctA. May act as a co-sensor of DcuS.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAIPLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGLAGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQMAHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCAVMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIRTLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATAAIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSEAHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAPVVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAFQRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL
The following text describes a protein:
Function:
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices precursor mRNAs to produce their mature form which then induces transcription of UPR target genes.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MMRRPPSQGRWSASHQKLLLAFAFILIPWLQLADAQQQPQQPQIRIHSQRGDAPLDKVADDANTRWYATHAAPDVHPEAKFDTVNRKQKQQSTASPQQHQKYRRAPYDYASKDKAQNRYAQHPIRESEKPNYVKVPNDASALATLAPAQPVRAPHTSRHHWPSSSAASGLASPQNARSLEDWEVEDFVLLATVDGDLYASDRKTGRHLWHLEVDQPVVETKHYRTNNSVLDDDYRPVDHYIWAVEPSRDGGLYVWIPDSGAGLVRTGFTMKHLVEELAPYAGDEPPVVYTGDKKTTMVTLDAATGRVLKWFGSSGSQVNEAESCLRPNAFDDRDTTECSSMGTITLGRTEYTVGIQRRDGRPIATLKYAEWGPNTFDSDLYQQYHASLDNHYITSQHDGRIYAFDKSQAENDLPLYTHKFSSPVARVFDVCRPWDANAGSNPELVVLPQPPIPALDESTVKMRSNSIFLNQTESGDWYALSGRAYPLILDAPVAQISRDDLWDMAHAFDSINPNKLSKALVGTHFLNPVKSTGYHQPPTLPAGALDEYYEDLENASNNAHAVTNTVPEEPTIITKVKALPQSAANSVIDFVSNPILIIFLIGSLIYNEKKLRRSYHRFRTHGTIKDVYPFFVIESEAGDESGDDKDGVFPSSPSPRSQPQDQNAEDHLSRHKVERNAGDQDKVKDNRSLHDVSDTLEPSNKTVEKTADVVKQVDVAGPDAPSTDSNGAAPEKKKKAHRGRRGGVKHRKGRPTDGSQSHENDPALTTVDEAVSNAKKLGDRPSLEPDVMTIYNDMQAVTGSVISMGNIEVDTDVELGMGSNGTVVFAGRFDGRDVAVKRMTIQFYDIATRETKLLRESDDHPNVIRYYSQVQRGDFLYIALERCAASLADVIEKPYAFGELAKAGQKDLPGVLYQITNGISHLHSLRIVHRDLKPQNILVNLDKDGRPRLLVSDFGLCKKLEDRQSSFGATTGRAAGTSGWRAPELLLDDDGQNPAAIDSSTHSGSHTILVGDPNSLSNGGRATRAIDIFSLGLVFFYVLTNGSHPFDCGDRYMREVNIRKGNYNLDPLDALGDFAYEAKDLIASMLQASPKARPDSREVMAHPFFWSPKKRLAFLCDVSDSLEKEVRDPPSPALVELERHAPEVIKGDFLKVLTRDFVESLGKQRKYTGNKLLDLLRALRNKRNHYEDMSDSLKRSVGSLPDGYLAYWTVKFPMLLLTCWNVVYNLEWEKTDRFREYYEPAGL
The following text describes a protein:
Function:
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Plays a critical role in the nucleocytoplasmic transport of viral RNP by interaction with other viral proteins. The nuclear export signal is masked by the interaction with the phosphoprotein P. Delays the host cell cycle progression by interacting with the host CDK1-cyclin B1 phase in late G2. Inhibits host NF-kappaB activation.
Miscellaneous:
MISCELLANEOUS: Isoform P38 does not have the nuclear localization signal, nonetheless it is localized in the nucleus.
Subcellular Localization:
Virion. Host nucleus. Host cytoplasm. Note=Shuttles between the host nucleus and cytoplasm.
Sequence:
MPPKRRLVDDADAMEDQDLYEPPASLPKLPGKFLQYTVGGSDPHPGIGHEKDIRQNAVALLDQSRRDMFHTVTPSLVFLCLLIPGLHAAFVHGGVPRESYLSTPVTRGEQTVVKTAKFYGEKTTQRDLTELEISSIFSHCCSLLIGVVIGSSSKIKAGAEQIKKRFKTMMAALNRPSHGETATLLQMFNPHEAIDWINGQPWVGSFVLSLLTTDFESPGKEFMDQIKLVASYAQMTTYTTIKEYLAECMDATLTIPVVAYEIRDFLEVSAKLKEDHADLFPFLGAIRHPDAIKLAPRSFPNLASAAFYWSKKENPTMAGYRASTIQPGASVKETQLARYRRREISRGEDGAELSGEISAIMKMIGVTGLN
The following text describes a protein:
Function:
Transcription factor which regulates nonfermentable carbon utilization.
Subcellular Localization:
Nucleus.
Sequence:
MTKKLTPQEKKNRKPAVRACVFCHQKHLQCSNERPCKNCVKRNIAHGCQDIVRKRVKYLTGESVPGAVSNKQSTPRKKLKTGPVSTSVSPMDSVKSELTTPVESSNHFPPPMSSSVDALPTTQHSAIEIPPNDQPISDILEVPPLFDSSHMISSEAPETNITLTTQNLITPDPLSFHTNTVSNTTTDVLNKLLNDNYETESMLSANNSNGDHLLGMAHTSSGHLSNGQQFQSNYLNEEYMMLGDIILQSKQASPSPSNTSTSENNTNTLSPSSFGYISNINFEDFNQPKRKVVQKLKDSRPFISLGFTADLAPHDNNNNTDYYDDKMTNNITGKTEEGPGNPIINYNTKFTTDYVPPSITNNLYKTASDLYSKELKNFYYPLSYHALTKLLKVIFGGNDLSPEEKQEKRSKLLIILKLIASYRPTFIAAHRDLIQEDLLMLEMTLQRSLLDYKKLAELNSSPTIMWRRTGEIISITEDMALLLEHSSFDLLKERRFIFELMDDNSIVDYFNLFANIAVGNLKSVIQTAIQMKTKSSNLIKFTCVFTIKRDIFDIPMIVIGQFLPIV
The following text describes a protein:
Function:
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Sequence:
MQRRRRPPPPASQLPEGCGGGGGGRGGSEEVEVQFSAGRLASAAAVSAAAAAARSTEEEEERLEREHFWKIINAFRYYGTSMHERVNRTERQFRSLPDNQQKLLPQFLLHLDKIRKCIDHNQEILLTIVNDCIHMFENKEYGEDGNGKIMPASTFDMDKLKSTLKQFVRDWSETGKAEREACYQPIIKEILKNFPKERWDPSKVNILVPGAGLGRLAWEIAMLGYACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPISFPDVDPHSLPPGSNFSMTAGDFQEIYSECNTWDCIATCFFIDTAHNVIDYIDTIWKILKPGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFQVEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ
The following text describes a protein:
Function:
Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.
Subcellular Localization:
Lysosome membrane; Single-pass type I membrane protein; Lumenal side.
Sequence:
MTNLVLVFAAFNLLPLFVLVSSADYNTFLDVEQKNYDRNVTTTINPKCPTNECVNFTLVHVQQEGIADVLHHIWTMENVPTFFYARTELNTEMLIDWEKMLSGNYSQAISFNKEPQYFAAVLIFKFFMYNDLNDTGVIPETDNFDIVSYSTKKMSWELKSSNCSGNISASVAFRLRSYDGVELDSSSNIEITLTAYGTRGRSPILPHLAFTENSTQVDFVFDHVETKESFTNARLAMELAAVVSEPDSRFTLNVSQSLDDEYTPGVFKLMEIHSALNQHWIQWRPVCYTSTQRDIGDSTGLYQTDIRNVSDDNILDNTLLEWLSLDLDTRFLLMKGFNVSFGVEGDGFYRASNYTAWTLVTGHGRPVGDQFSLMVILVMAIGLGLPAIVLILGGAAIALRNHRNSKDDLLLSD
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.
Sequence:
MGYEEAFPAELREYYRKLFGSEAEEIMASLRTPVEKYYIRVNTLKTSRSELMRRLRREGLKPKRSPYLEEGIYFEREGPNFDDDYDPGLKKVVANKFASESVYQGAMLYAPGVLKADKGIKPGDEVEIRDPRGLLVGIGIARMSGKEMITATRGLAVEVTLPKFKLPSLSELESFKEGLFYAQSLPSMVASRVLEPSEEDLIIDMAAAPGGKTSHIAQLMQNRGEIIAIDKSRNRLRKMEEELKRLGVKNVRLIHMDARKLPELGIEADKILLDAPCTALGIRPKLWETRTPKDIEATARYQRAFIWAAIKSLRKGGTLVYSTCTISYEENEANVKYMLQKGLKLEEQSVFIASHGIDMEGVQRFYPNRHLTQGFFIAKLRKV
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Sequence:
MGVCQSFVLTDEMKDQIKVNKEIEKQLEKKKNMQLEQTVLLLGPGESGKSTVMKQMRAMTGNYTKTELHERKVLIIQNLCQFSEMLLEYVREYILEMTEDDDKRYTVMCEELKMAVIHDGIMRPELADTLKEFWGNSAIQDAYSKRDTFHLTDSAKYFFDNIDRIKLPGFEPTNQDIVHIRVPTTGVAQVEVIMNNIKLMICDCGGQRSERRKWYHFFDEADAVLFVAAISEFDQKLAEDEETNRMHESIRLFWTVFNGKFFKKAAVILFLNKIDLFEEKVKHVKIKDYFPKFEGANTVSEGTKFFRRQFREGIHPDFKKRMYTHETCAISDQVQIIINTVIDTVIQDNLKDTGMI
The following text describes a protein:
Function:
May play a role in fatty acid biosynthesis and insulin sensitivity.
Subcellular Localization:
Mitochondrion.
Sequence:
NGVATLTLNNPAKYNVMTWDMLQLLQNQLDTISKEDRIKVVVIRATGKAFSAGHDLREIQLQNGNDEKQRSLFQRCSNLMISLNRLPQPVIASVQGVATAAGCQLVASCDLAVSSEDAMFGASGINVGLFCSTPAVALSRSMHPKQALQMLLTGDLITSDEALSYGLVNKVVSSSMLSTETTKLATQIASKSSHVVRLGKKMFYEQLAYDNLDEAYAFATERIVCNLKHPDTMKGIDDFVSKKPKS
The following text describes a protein:
Function:
Displays ATPase and GTPase activities.
Sequence:
MSTGKETAGAHEAAIPELVIISGMSGAGRSTAAKCLEDLGWFVVDNLPPALIPTMVELGARSQGNVARIAVVVDVRGRRFFDNLRESLADLDARGVTRRIVFLESSDDALVRRFESVRRPHPLQGDGRIVDGIAAERELLRELRGDADLVIDTSSLNVHELRAKMDAQFAGDQEPELRATVMSFGFKYGLPVDADLVVDMRFLPNPHWVPELRPFTGLNEEVSSYVLNQPGAKEFLDRYAELLQLIAAGYRREGKRYVTVAVGCTGGKHRSVAMSEKLAARLAAEGVETVVVHRDMGRE
The following text describes a protein:
Function:
Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MKNDVVRWSRQPTSNTTNSSSSSRSDSNSTHKHRSKSNKLNARQLGSNAARSCQQRSSVATTLEDEQQTIIECDIGNFNFDCNLFKTSFLTQHKQKRSGKSSSKSKSNRSRPLAKTKAVFLLALQFSAVVFLCNINVGFVAGSVATAASSAGGSSPAAPSSAPSSPPTVAVPPPPPPSSALKVDPNGQSPVLPPYVLDYETGGKAKLTPNNGKFGQSGSSGSNNNHIVGHYTHTWAVHIPNGDNGMADAVAKDHGFVNLGKIFDDHYHFAHHKVSKRSLSPATHHQTRLDDDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFNDSKWPQMWYLNRGGGLDMNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDSNRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGDVTDAVEARSLSLNPQHIDIYSASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNSIWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQVVTTDLHHSCTVSHTGTSASAPLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPANLKDPSWSRNGVGRRVSHSFGYGLMDAAEMVRVARNWKAVPEQQRCEINAPHVDKVIPPRTHITLQLTVNHCRSVNYLEHVQAKITLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSRSGFNQWPFMSVHTWGESPQGNWQLEIHNEGRYMAQITQWDMIFYGTETPAQPDDVANPSQSNQFNLYGNDMAHNDVEYDSTGQWRNMQQVGEVGMTRDHSNTAACLKWSDRKCLECNDSAYMFEDQCYDVCPVHTYPLDKFQAEEDEQDDEVTRGPVNPYSSSPMDHSLLMSNSLDDKQDPLQAEDRRRRSSLTQLVEVPSRVCAACDRSCLECYGALASQCSTCSPGSQLRKILNETFCYAYVVRSTGMASVVDISKMDDRDTQQYMTGTTVLLLVSVIFTLMGVAVAGGIVYHRRAMARSNELYSRVSLVPGDESDSDEDELFTAHFPARKSGVNIYRDEAPSEKIFEEDEISHLVP
The following text describes a protein:
Function:
5'->3' double-stranded DNA exonuclease that could act in a pathway that corrects mismatched base pairs.
Subcellular Localization:
Nucleus.
Sequence:
MGIKGLLGLLKPMQKSSHVEEFSGKTLGVDGYVWLHKAVFTCAHELAFNKETDKYLKYAIHQALMLQYYGVKPLIVFDGGPLPCKASTEQKRKERRQEAFELGKKLWDEGKKSQAIMQFSRCVDVTPEMAWKLIIALREHGIESIVAPYEADAQLVYLEKENIIDGIITEDSDMLVFGAQTVLFKMDGFGNCITIRRNDIANAQDLNLRLPIEKLRHMAIFSGCDYTDGVAGMGLKTALRYLQKYPEPRAAIRAMRLDKSLKVPVSFEKEFALADLAFRHQRVYCPKDKTLVHLSPPERELSVHEDAFIGSFFDNQLAIDIAEGRSNPITKCAFDIKDSSMQSFTKTTITISKRKGISKTDISNFFMKSIPPSKRPTKSTSLIDVTNVKVQRTHLANDISSEKQSIKSANEKAYVTPKSNSLKPGFGKSLSDISNSATKNENVPFLPPRTGVSKYFKLQKNTEKEIDEQVPSQSNNTTPTSAKSDSASPQNWFSSFSYQTPNSASPPFSSLSHTLPISALAKIGHDALNRKNHASLPSRRIVYKPPSSPSTPISMNPRPKGILSLQQYKFR
The following text describes a protein:
Function:
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity (By similarity). Required for DNA replication and accumulation in plastids and mitochondria. May be required for DNA repair in both organelles.
Subcellular Localization:
Plastid, chloroplast. Mitochondrion. Note=Targeted to chloroplast when translation is initiated at the AUG initiator start, and to mitochondrion when it is initiated at a non-canonical CTG leucine codon located 21-bp upstream of the initiator methionine codon.
Sequence:
MAMGVSLTSHNNPLLRHLSPSSSWVSRSSSRLSSSPLPSFLFPCRRTLLQRKLASTDGNVGYCTTTVCQGFQHSVHQRSSSVVFNGEWELRSESNKVRMVPKIIKVGNQTEVAETHQVPGTVSAWREEANKLRERNGQIARNLDDNGYFNGSVPIISSAPSYETSQKIDYEFKPRGTTRSTTATLNKELIGITQSEPVVSLPRKGLDVGDNMDVNPKGEGIQRPLISDKSSGTANGNKNTVAISKVERSTEPSNVRENLGKIYDKVLIVDNVQAAKDTVAKLVNQFRNHVHSCDTEVSGIEVKEETPVDHGELICFSIYCGPEADFGNGKSCIWVDVLGENGREVLAEFKPYFEDSFIRKVWHNYSFDSHIIRNHGIEISGFHADTMHMARLWDSARRIKGGYSLEALTSDPKVLGGTQTKEEAEFLGKISMKTIFGKRKLKKDGSEGKIVVIPPVEELQREDREAWISYSALDAISTLKLYESMTKKLQLMDWHLDGKPVLGRTMLDFYHEFWRPFGELLVKMEAEGILVDREYLAEIEKVAKAEQQVAGSRFRNWASKYCPDAKYMNIGSDTQLRQLFFGGISNSHDEVLPVEKLFKVPNIDKVIEEGKKTPTKFRNIKLHRISDSPLSTENFTASGWPSVGGDVLKELAGKVSAEYDFMDDVSDISLEEVVEDDDVETSETQKSKTDDETDTSAYGTAYVAFGGGERGKEACHAIASLCEVCSIDSLISNFILPLQGSNVSGKDGRVHCSLNINTETGRLSARRPNLQNQPALEKDRYKIRKAFVASPGNTLVVADYGQLELRILAHLTGCKSMMEAFKAGGDFHSRTAMNMYPHVREAVENGQVILEWHPEPGEDKPPVPLLKDAFGSERRKAKMLNFSIAYGKTAVGLSRDWKVSTKEAQETVDLWYNDRQEVRKWQEMRKKEAIEDGYVLTLLGRSRRFPASKSRAQRNHIQRAAINTPVQGSAADVAMCAMLEISINQQLKKLGWRLLLQIHDEVILEGPIESAEIAKDIVVDCMSKPFNGRNILSVDLSVDAKCAQNWYAAK
The following text describes a protein:
Function:
Component of the translocation and assembly module (TAM), which facilitates the insertion and assembly of specific beta-barrel proteins into the outer membrane; In addition, is involved in outer membrane lipid homeostasis (By similarity). Likely transports phospholipids between the inner membrane and the outer membrane (By similarity).
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Sequence:
MTEQIQPSETSPKSPEKPNKKHWVRKAVCIGSAVILVPVLGVAGALSFDAGQKSLIQLVDKMLDSFSVEQVEGGLQNGLVLKNVRYQTAGIETHIAQARLQLDFGCLFSREVCLRDFTLNKPTIAINTALLPPSAPDNSKSGSMKRISLPISINAENLVMQDLSVNIDQTSITLGNFKSAVSLNNEKGLTIAPTEINDISVIAKKLSEVKSEPKAEQPNKPVDWAAIEQSLTPAFLGNVSEIILPFDLHIPEISGKNWQYQAVNEKGETLQSVEMSSLIAQADTVDNQLQLQKLAVESSLGNLSSQGKLQLDGDMPLDLTLKSHLEPLKSDGKEILPASDVDLTLSGSLKKSTALSLKTKGVLDAELNGNVQLAQDKMPLNLTLNVAKGQYTFVNTMTPLKINDVTLKLTGDLLNYHAELKGDVAGMNYIPASQVELNADGKLYEVTVNKLGIDSLDGKSEFVGNANWKNGANWDIQADLEKMNIAFFVPVMPATLSGKLHSRGFAGSQGWQVEVPVADLNGMLSAKPISLKGSATLNQNVLLTVPDLQIKYGENYLKASGVLDDHSDFALDINAPNLRGLWSDLKGRVKGRVAISGQITTPNLDLDLTSSNLHLQGFQLAKASIKGHINNASLSSGKLNIKAEQLHYGGNIKLHLLDLDLSGDEQNHKLILKSQGEPVAANLQINGHFDRTLEQWKGTISQVKFETPIGDVKSNQAIAVSYDNKQTQANIASHCWQNTDVELCFPQAFNAGKQGNIPFQFKRVNLDLVNKLIEQNSLKGNLQVQGNVAWFTDKPFQFTANVDGNHLAFSQKLDYRTFKLYIPKLTLNADIQNNNLVLKTDINVHNQGRIVGDIHLNDLAKNRQLGGTLAIERLNLSIANQLLTSGESVNGEVVSKLSFGGNLEKPLLNGDFNIRNIRTKLKSMPVNITDGDIALRFNDNRSTLQGKIKTVDSHLNLTGRANWANIEHWTTELNAQANNFNVDIPSMAKLRFSPNITIKANPKELNLSGTVDIPWARIKIDSLPDTAEPVSEDEVILNGPHKSKEELIKREFAAKTKSGMEIRSDLRINIGKDVSLDAYGLKTNLDGLLSVKQDKGNLGLFGQINLTKGRYASFGQDLLIRKGLISFSGQATQPTLNIEAIRNPETMEDSKITAGVRVIGIADSPEVTIFSEPSKPQDQALSYLLTGRSLESSGEVGSTGSVGAALIGLGISKSGKLVGSIGEVFGIQDLNLGTSGVGDKSKVTVSGNITNRLQIKYGVGLFDGLAEVTLRYRLMPQLYFQSVSSTNQVFDLLYKFEF
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium.
Subcellular Localization:
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Sequence:
MSGKDRIEIFPSRMAQTIMKARLKGAQTGRNLLKKKSDALTLRFRQILKKIIETSFVTLDEAIKITNRRVNAIEHVIIPRIERTLAYIITELDEREREEFYRLKKIQEKKKILKEKSEKDLEQRRAAGEVLEPANLLAEEKDEDLLFE
The following text describes a protein:
Function:
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.
Subcellular Localization:
Secreted.
Sequence:
MRVDSTVLALVALATDCLGLAIKSNEPELLRRDALPIYKNASYCVDERVRDLLSRMTLEEKAGQLFHKQLSEGPLDDDSSGNSTETMIGKKHMTHFNLASDITNATQTAEFINLIQKRALQTRLGIPITISTDPRHSFTENVGTGFQAGVFSQWPESLGLAALRDPQLVREFAEVAREEYLAVGIRAALHPQVDLSTEPRWARISGTWGENSTLTSELIVEYIKGFQGEGKLGPKSVKTVTKHFPGGGPMENGEDSHFYYGKNQTYPGNNIDEHLIPFKAALAAGATEIMPYYSRPIGTNWEAVGFSFNKEIVTDLLRGELGFDGIVLTDWGLITDTYIGNQYMPARAWGVEYLSELQRAARILDAGCDQFGGEERPELIVQLVREGTISEDRIDVSVARLLKEKFLLGLFDNPFVNASAANNIVGNEHFVNLGRDAQRRSYTLLTNNQTILPLAKPGEGTRFYIEGFDSAFMSARNYTVVNTTEEADFALLRYNAPYEPRNGTFEANFHAGSLAFNATEKARQAKIYSSLPTIVDIILDRPAVIPEVVEQAQAVLASYGSDSEAFLDVVFGVSKPEGKLPFDLPRSMDAVEAQAEDLPFDTENPVFRYGHGLEYEDN
The following text describes a protein:
Function:
Reductase involved in lignan (-)-hinokinin biosynthesis. Catalyzes the enantioselective conversion of (+)-pinoresinol into (+)-lariciresinol and of (+)-lariciresinol into (-)-secoisolariciresinol. Abstracts the 4R-hydride from the NADPH cofactor during catalysis. Has also a low phenylcoumaran benzylic ether reductase activity.
Miscellaneous:
MISCELLANEOUS: Knock-down mutants of PLR_Lc1 show unequivocally that (-)-hinokinin is synthesized via the (-)-secoisolariciresinol/(-)-matairesinol pathway and not via the piperitol/sesamin pathway.
Sequence:
MGSLNESSKVLVIGGTGYLGKRLVKASLDAGHDTYVMHRPEIGVDIEKVQLLLSFKMQGAHLVSASFDDHRSLVDAVSLVDVVICAISGVHIRSHQILLQLKLVQAIKEAGNVKRFLPSEFGTDPARMGDAMEPGRVTFDDKMVVRRAIEEAAIPFTYVSANCFAGYFLGGLCQPGSILPSRDHVTLLGDGNQKGVYVDENDIAAYTLKAIDDPRTLNKTLYIKPPKNILSQRQVVGIWEKHIGKQLHKTLLSEQDFLAAMKEQDYAEQVGLTHYYHVCYEGCLTNFEVEQDQEASKLYPDVRYTTVEEYLKRYV