lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Centriole-enriched microtubule-binding protein involved in centriole biogenesis. In collaboration with CEP295 and POC1B, is required for the centriole-to-centrosome conversion by ensuring the formation of bona fide centriole wall. Functions as a linker component that maintains centrosome cohesion. Associates with CROCC and regulates its stability and localization to the centrosome.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Midbody.
Sequence:
MATGDVKGCIRKLEQRLRTLNYPRDVDYTGLIKGDPSASLPIISYTFTCYSTSIAEILISFGIELTTKSDLRFIEAVYKVLRDVFNYKPILTKQQFLQCAFSERKIQIICDIVDCVVKKHKEITGQNKVKSQLVKKVVSAKDQCEVFYPEDVSVQPSVKTTQKKPLVERHAGSEFLLPTKCYSSALVEDIEEEEPTSDSEGGSHLEHEMESPFETAETTPNSEQIELLRKQLAECQEKLQRLDCVEQRLQSLETSMKGKIIIDETDWNNLLSRVLLLETEGLLQSKKTDFSVPSEFACISEQRTSSRMTNEICSNLKTKADIPESHHQSSGYSSVLSADTSPIAIDINYSSLTEDSNETTKQRMERITKMMEETSKLLKCSNNT
The following text describes a protein:
Function:
cAMP-responsive transcriptional activator regulating late gene expression. Essential component of the developmental switch between early and late development. Binds to a number of CA/GT-rich gene regulatory elements.
Subcellular Localization:
Nucleus.
Sequence:
MLSTHHHQGNSSSSSSSSSPSQTIGGSDLSNISALPLPLPSIFTTAQNQMNPPILFPPTSSLLGGSSNTPSFLLPPSSIMSSNVFPSHDGQYPDMPNMVDQYQIHPNQNPHYNYQYQLMFMQQQAQQNQPPQQNQQQQHHQQQQQQPQHHQQMQQQQHHQQMQQQQQHHQQMQQQQHHQQMQHHQLQQHQHQHQQQQQQQQHQQQHHQQQQQQQQQHHQQQQHHQHSQPQQQHQHNQQQQHQHNQQQHQQQQNQIQMVPQQPQSLSNSGNNNNNNNNNNNSNNNNNNNNNNNSHQLNNLTLSQNNTSGSNTPSPSTKGKRKHHETSNSEKKDSSGQTIPKCTRCNEAASWKHDKRRWWCKECKKAFTPGITKMQQVPQQAQLQPLQNHNQIIPQLWDSQQNNSSQNTPPTQPQNNMNQINHQLLQQQHQQAQLQAHLNLTASNQQVPPQLQQQINGGLPNNNNSLITQNTLNSLSTSVSCPPCPLCRGISSWKHDKKRYFCKECKKPFTPVGAGLSPSSSPSSPKKKSNITPITTSSTSSSSSTPSIINNNNNNNANSSKNNTPKKQLSPPPSVLQSPSSSSISQSPLQLNYQTPTYSPNPSLPSIGGNLNSLANSIKPDGGILISGLSPPKSSSSLNNLNSFSNTGALLSSNGINLANLGNPLSQLNKKQKKRSDKDINDGGVQVLVSCVDTNVNNCSSIIPDGDSW
The following text describes a protein:
Function:
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
Sequence:
MKKNIEPCYYGDYLQLDKILGAQDLQSEKYGDGAHEEMLFIIVHQVYELWFKQVLHELNAVIDTFNQEAVKDQQLTQVVHRLQRIIQIQKLMNDQIAIMETMTPQQFLSFRDYLVPASGFQSIQFKRLEISLGLKREFRIDFDKQSFYNRLTDKDRALLENLENKPSLFELVDKWLSRMPLLKTEDFDFWQYYKDAADEMLKDDHHTVSTSDMLSDTEKRQEIKDLQATMENFDALFNETQFEKLRGEGKFRLSHNALLSALFIKQYSEEPIFNLPFQLITALTEIDEQLTIWRYRHAMMVQRMLGTKIGTGGSSGHHYLKKTTESNRIYLDFFNMATFLLPKSALPDLPESVRRRLGFYLQ
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MAKVSDLYDVTWEEMRDKMRKWREENYRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYSRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDALQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTIHTTTYTVNSLPEVKYTQGGLENLEYSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQITQS
The following text describes a protein:
Function:
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type IV membrane protein.
Sequence:
MSGLGLFGGGGGRKVPEREERGRGRTSADGEGEAKAEAAALPQSRPEDGGRRRPRPAPLMPPLCARPLLAEQLADDRMALVSGISLDPEAAIGVTKRLPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSTEEEHAIEITTQEITQLFHRCQRAVQALQCRARNCTEQEERVLRNVVSSLAQSLQELSTNFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGEDNTLYDRGFTDDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTLLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIVIVLLVVLVGVKSH
The following text describes a protein:
Function:
Structure-specific DNA-binding protein involved in DNA repair by promoting RAD51-mediated homologous recombination (By similarity). Acts by stimulating D-Loop formation by RAD51: specifically enhances joint molecule formation through its structure-specific DNA interaction and its interaction with RAD51 (By similarity). Binds single-stranded DNA (ssDNA), double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures: has a strong preference for branched-DNA structures that are obligatory intermediates during joint molecule formation (By similarity). Involved in mitotic recombination-dependent replication fork processing. Also involved in meiosis by promoting DMC1-mediated homologous meiotic recombination (By similarity).
Subcellular Localization:
Chromosome. Nucleus. Note=Colocalizes with RAD51 to multiple nuclear foci. Colocalizes with DMC1 on meiotic chromatin.
Sequence:
MARMVRRNRKIVNYSEFGDFEDGDEDFACIAAPLTKKSRTQPKEPKKENKKKQKTQKEFTSSQKQSPIGRTSLDDSFCERDLNVTLALSIKEKSANILEVQNSKEQGQVLDDDIPRNGCRQWTAASKAFSHQKLLTIDSCDREHVTDSEPVTIPDEESEEDSDYREGNDEDCAMEKMKINGMKKKIKRQTRKEKKTPKSENNTTVMELKSEQTQKMMSTSSEPVGRPLYTSSPVTNKKPKWVPPGRACAVSFL
The following text describes a protein:
Function:
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MSALSQAQRKKGDAFLSEASSTLSKSTWFASSTERKYEDAAESYVKAANAYKVGGCHDEAGSAYQKAAELYKDKLKSLGEASKCLSDAGACLKKTHPTEAVGCYRSAVTLLCDAGRLSQAAKLSKEIAEIFENDDSVTAAIASYQQAAELFEMEQAKSQASQCLQKVAELSSGALNPPELLRAAEIYENLGRQCLESNLLKYNAKSHFLNGVMCHLANHDSIGASQALSRFDNLDYTFGESREGKFAQQLVETVEGFDPEGFATACFEYDRISKLDPWKTSMLVRVKRGIEEEGGGGEGEDDLDLT
The following text describes a protein:
Function:
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
Subcellular Localization:
Nucleus, nucleoplasm. Cytoplasm, P-body.
Sequence:
MEEGELSTGAAAGGGDELYNALHQRLVASGEWQRLLILLRRMLDESGWESEFQAYATTKAKQQPVLSVPDLIDVLTPHAQDTLPAHVRAHLLDKLTNFLDRNLEDA
The following text describes a protein:
Function:
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
Subcellular Localization:
Cytoplasm.
Domain:
The PRC barrel domain binds ribosomal protein uS19.
Sequence:
MTDTQNRVAMGYIKGVFGIKGWLKIAANTEYSDSLLDYPEWHLVKDGKTISVTLEAGKVVNGELQVKFEGINDRDLAFSLRGYTIEIPREAFAPTEEDEYYWTDLVGMTVVNKDHTVLGKVSNLMETGANDVLMIDGEHGQILIPFVSQYIETVDTGSKTITADWGLDY
The following text describes a protein:
Function:
Plays a role in the expression of late transcripts bridging viral DNA replication and late gene expression during infection. Functions concordantly with UL87 to initiate transcription from over half of all active viral promoters in late infection, without affecting host transcription. Acts on and binds to viral early-late and late kinetic-class promoters.
Subcellular Localization:
Host nucleus. Note=Localizes in replication compartments during virus infection.
Sequence:
MMARDEENPAVPRVRTGKFSFTCANHLILQISEKMSRGQPLSSLRLEELKIVRLICVLLFHRGLETLLLRETMNNLGVSDHAVLSRKTPQPYWPHLYRELRQAFPGLDFEAAVFDETRAARLSQRLCHPRLSGGLLTRFVQRHTGLPVVFPEDLARNGNILFSLGTLYGHRLFRLAAFFTRHWGAEAYEPLIRIICQKMWYFYLIGTGKMRITPDAFDIQRSRHETGIFTFIMEDYRTFAGTLSRHPHRPHPQQQQHHHPGPPHPPLSHPASSCLSPEAVLAARALHMPTLANDV
The following text describes a protein:
Function:
Probably participates in a plant defense mechanism. Inhibits the cytopathic effects of the human immunodeficiency virus.
Domain:
The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.
Sequence:
AIPCGESCVWIPCISAAIGCSCKNKVCYR
The following text describes a protein:
Function:
Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity).
Sequence:
MAGRGGRDPRRGYDGGYGYPRGGGGQGGTNRGRDGQRGGGRNGPRGGRFPGGRGVEPRRGGDVLGGGQGGGRGTTAGAGGLVRGGSELAVGAELRRRVPTCHVNDFPELGIGGTPVLVRRWRPRDHRDQHDHQSQRHHHRHHHHQRQRHHHHHQRQQRRGSRTRDPRVRRGPLRIPYGEDEKEEPPATPIASSNKNKREEPPTKHRPMARPPGGGGPLSKGEVKLLVNHFSVDYPKESTFFHYEIRIKLGDGPNRKLSKAELLTVKNELFEHESLQELSSAVAYDGERNLYTCAELPEDCIVPVSKFRVKDSSRTYIVSVKLKKPLPLSQLLEQRPGPRDVMQGLDVIVREASSFGKIVLGQGFYPQSGSEAISDSNIVALKGTQQSLKCTQKGLILCVDYSVLPCWKAGSVLDLVKTMKFMEYPLLEDQLKKLNNALKGLCVTVSHRKTEEKYTVKGLTDKPADQITFKDSKSGQTTKLIEYYKETYKKEIEHPMLPCLDLSKSKSKQNYVPIEFCNIPEGERYPVARLDDKKSDNKGEQEKPSTKTTLRKISIKVASSRKEEILDLVGNAQDGPCRGKIAQRFRISLDAAMMEVTGRILAPPTLELGTGTSRGQTFKFTIHQDDCQWNWKLKKYDKRVVAHGGTLNCWGVVDFSEGDLESKFIDKVVRKCSALGMVMTRKPCYEHVSNMEVLSDPKSLRDALIEAKRAAEEEDKKLQLLFCPMLNRCHGYKTLKLMCETELGIQTQCFLSTAAKLDEKRQDQYITNLALKINGKIGGSNMQLDPDSIPVVSAKDFMFIGADVNHPPPGNVSKDIPSIAAVVASVDKGASKYVTRIRAQYHRCEMIQNLGDICKELIGAYEKVNKKKPDSIIYFRDGVSDGQFDMVLNEELADMENKIMVGDYPKITVIVAKKRHHTRLFPKDRNQRQTKNGNVLPGTVVDTDVVDPTAYDFYLCSHKGEVGTSRPTHYYSLLDEHGFASDDLQKLVYNLCFVFARCTKPVSLATPVYYADLAAYRGRLYYEGMMMLQPAASAASASEAMMPAAQPQAAAAAAAAASPSSSAASSSEGMTASQPQAPAAEAASSSAGAADFRELPPMHGDLLNNMFFL
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane; Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGGLSAQHPWAFTFGLLGNVISFMTYLAPLPTFYRIYKNKSTQGFQSVPYVVALFSAMLWIYYALLKSDEYLLITINSAGCVIETIYIVLYLAYAHKQARIFTAKILLLLNVGVFGLILLLTLLLTAGERRIVMLGWVCVGFSVSVFVAPLSVIRLVVRTRSVEFMPFSLSLFLTASAVVWFLYGLLIKDKYVALPNILGFAFGVIQMGLYALYRKATPRPAPKEVDAPVSDDGAVKAPEHVVNIAKLGQAVELPPVKEGAAKKSGVASASDDTKGSLEKLDKAIHVEQV
The following text describes a protein:
Function:
Can use enol isomers of phenylpyruvate, 2-hydroxy-2,4-pentadienoate and (p-hydroxyphenyl)pyruvate as substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIALQQIQPESWQAIWDAEIAPQMEALIKKPGYSMNA
The following text describes a protein:
Function:
Tube-forming lipid transport protein which mediates the transfer of lipids between membranes at organelle contact sites. Required for retrograde traffic of vesicle clusters in the early endocytic pathway to the Golgi complex.
Subcellular Localization:
Cytoplasm, cytosol. Early endosome. Note=Localizes on a subpopulation of vesicle clusters in the early endocytic pathway.
Sequence:
MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINKVFCNKASIRIPWTKLKTHPICLSLDKVIMEMSTCEEPRSPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRIGAKAFNASFELSQLRIYSVNAHWEHGDLRFTRIQDPQRGEVLTFKEINWQMIRIEADATQSSHLEIMCAPVRLITNQSKIRVTLKRRLKDCNVIATKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSMAPEPTQSSTVVASAQQVKTTQTSNAPDVNDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHAKEKESNRRITGGAMQLSFTQLTIDYYPYHKAGDSCNHWMYFSDATKTKNGWANELLHEFECNVEMLKQAVKDHNVGSPPKSPTHASPQHTQTEKDYPLKGTCRTPSVLSQQSKAKLMSSSVVVRLADFNIYQVSTAEQCRSSPKSMICCNKKSLYLPQEMSAVYIEFTEYYYPDGKDFPIPSPNLYSQLNALQFTVDERSILWLNQFLLDLKQSLNQFMAVYKLNDNSKSDEHVDVRVDGLMLKFVIPSEVKSECHQDQPRAISIQSSEMIATNTRHCPNCRHSDLEALFQDFKDCDFFSKTYTSFPKSCDNFNLLHPIFQRHAHEQDTKMHEIYKGNITPQLNKNTLKTSAATDVWAVYFSQFWIDYEGMKSGKGRPISFVDSFPLSIWICQPTRYAESQKEPQTCNQVSLNTSQSESSDLAGRLKRKKLLKEYYSTESEPLTNGGQKPSSSDTFFRFSPSSSEADIHLLVHVHKHVSMQINHYQYLLLLFLHESLILLSENLRKDVEAVTGSPASQTSICIGILLRSAELALLLHPVDQANTLKSPVSESVSPVVPDYLPTENGDFLSSKRKQISRDINRIRSVTVNHMSDNRSMSVDLSHIPLKDPLLFKSASDTNLQKGISFMDYLSDKHLGKISEDESSGLVYKSGSGEIGSETSDKKDSFYTDSSSILNYREDSNILSFDSDGNQNILSSTLTSKGNETIESIFKAEDLLPEAASLSENLDISKEETPPVRTLKSQSSLSGKPKERCPPNLAPLCVSYKNMKRSSSQMSLDTISLDSMILEEQLLESDGSDSHMFLEKGNKKNSTTNYRGTAESVNAGANLQNYGETSPDAISTNSEGAQENHDDLMSVVVFKITGVNGEIDIRGEDTEICLQVNQVTPDQLGNISLRHYLCNRPVGSDQKAVIHSKSSPEISLRFESGPGAVIHSLLAEKNGFLQCHIENFSTEFLTSSLMNIQHFLEDETVATVMPMKIQVSNTKINLKDDSPRSSTVSLEPAPVTVHIDHLVVERSDDGSFHIRDSHMLNTGNDLKENVKSDSVLLTSGKYDLKKQRSVTQATQTSPGVPWPSQSANFPEFSFDFTREQLMEENESLKQELAKAKMALAEAHLEKDALLHHIKKMTVE
The following text describes a protein:
Function:
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum (By similarity).
Subcellular Localization:
Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
Sequence:
MARIFKFFVFLLIVFISNVLLLVESNEGDNSFSSKSIQLSLVSNWGETPSYLEAAEFLHNQDKSLFWKFIEEFNKIDFSTNYSDKIYYESTISLMKSVLSSNTQFLSEFLSIDLAMRTYSPRVETYRQLAISNMKLNNIEHSITTADNKTITLFNSGGWVQIKNKIITDVNEINESLFKDVAVVDDEENEFIRLYDFDHIFPTLANTVSSSSSSPSSIPIVILYVDIKSEFFKLVHPKLKQFSQMGKIKYCLRYVVQESNQKLNLQGYGYELSIKNLEYKVMDDSAIKKDIIIDGVKSKTIINIPNEDVQGFNFHKLQKRKPELTSKLSTFRSYLMAKSQEAKELKVWELKDLGIQSAQKIIQSGDPLRSLEYISQKFPTLSNSLSKITLNESLKSVIESNQKIIPSTTDQTLLLNGRLIDTNELSPIELSRIILEEYEHSTTIQQQGPLSSKTVQDIISAQLPIRIQLLPTKEELELNGGNEPFVSLNNLELDYIYRQWEPKLQSSVLDKPVTSPQDIFIRKNLLTTVIVLDWNNINTFEIIPEIQEMVQGNSLIPTRIQLLFNTKSNNNNNNNNNNNDQNSQTSNFIQGKDLAKVFLTIKNSNLGNRGAFFFITALNYFKKMYIPNELGITRSVLSSSFQAVLQQMGGSVRSLQHALTNTDFDNLLESSNQLIERLELLDTTTSQSTTTTTTTKILPKVFVNGVQVKYSNIDQLSFDLLVSLYDEFDNLKPLFKESILSTTTAQYYETILTSSYWKDNNLPFLKKLNSMISNEKYSHLITNSKNRNQEVDAQNVLKNLLYFRNNENKDEQNLLNLIVIGDFDHYNTRDISLELLRQLEKGELKNCKLTFISNPIDINSVVNTAGNENQILGKLITILKHYGKILTPQLVIGLFEKVQSDPTIIDSFKTMKQIIELSGFDIAANDIWVAQSVNLFKQSSKVCKQYLGIQSTNKSPLSILVNGRIITPPLSYDDAASFIQSDFKLLLEIEMIKAKKTFELLNSDPILKDKSNLKISDLLNKVQSLVGYYYNGNNQLDSNIKRKRIPNSLSISFSHKPPTLSSSSSSSSSNSNDVPLKFLMIINPFNKVSQKLVPMVREFSNKLNIPVDVILNPPVSLSELPLKTYYTYVIKLSSEFNNENVLYNQPLGIATDIPEDRVVTLALDIPSSWLVQPIIAKYDLDNIRLKDLGDEQVLTAVYELENIVIEGSANDMTTDNAPAGLELLLNPISTQTNKTQDTIVMNNFGYYQLKSNPGIWKLTIAPGRSSDIMDMVDHPNQKEKETFVIVPHRLVVIDSLYQSLSSLSVVRKAGQELRPILQPIDEYEKQKEQEKEQKLKQNSSGFFSNLFSSKNDATDSVATHQKKSNLDTIHIFSVASGHLYERFLKIMMLSVVKNTESPIKFWFLKNYLSPAFKEFIPEMAKEYGFQYELVTYKWPWWLRKQTEKQRIIWSYKILFLDVLFPLDVPKIIFVDADQVVRTDLKELWDMDLHGASLGYTPFCDSNKDTEGFRFWKSGYWRQHLAGRSYHISALYVVDLVRFRRLAAGDQLRATYDQLSRDPNSLANLDQDLPNYLQHYVRIHSLPQEWLWCETWCDQESKSKAKTIDLCNNPLTKTPKLENAVRIIDEWTTLDNEAKEFELKIDQSKHHRQIELDHQNQLPNSKPIENIDDILLNLAESQKDLF
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Sequence:
MFSWEASLSNELYFVRQYFYSGNYTKLFEIDTTSMSEKGLELTEIYMARAKLALGESLESIQSILTQKTPGSAAILALAGEGNMELIIDQHGNSDSVVQTLGAIFQIKNGSFDDAMDLLKKSVENLEAVALQVYIHLREHKIEAAEQTLKQALDWADEEIVLQLAQSWIKIVSGGVESYNDAFYVFEELNGTDSNPMTLTGMACADICLLRPEEALSSLKTALDSQPNYEEALSNMTTAITDLGPDAPSQAKNILSSFTNSSTLKLNDHLNEKAQEFDTFSTQFLSTA
The following text describes a protein:
Function:
Phosphatidylinositol 3-kinase homolog that regulates longevity and diapause. Promotes cell survival during embryonic development by recruiting akt-1/2 to the plasma membrane through the production of PtdIns(3,4,5)P3. Could function in the development or neuroendocrine signaling of the dauer pathway. Mediates susceptibility to enteropathogenic E.coli infection. May negatively regulate AYI interneuron neurite outgrowth. Plays a role in aversive olfactory learning when an odor is associated with food deprivation. Regulates this process by promoting the nuclear relocalization of egl-4 in AWC olfactory neurons after odor conditioning.
Sequence:
MSMGRSSSTTFRNRTASHGSRSLGSAETARIPRKLSSQLSHTHANILHPQLQTMMEQWQMRERPSLETENGKGSLLLSSEGVADMIVLSSFGEVISVVFPWFLANVRTSFDIKLSEFKHQLFEQIGPMKWGKHSTQPQDYAFRQLNNFGEIEVIFNDDQQLSCLELHGTFPMLFLFEPDGFNRDKELMCDISHCLGYSLDKLEESIDEELRQFRASLWTQTKKTCFERGVDGVDHYAFPEEQYFCVGEKCPTDLESKVKAAKLDYQLFWTKRKSEANEVWEKMYKITIDFDPEFNPQSLMRMFVKELQCMNLFDPEDPPDEEWILQLAGRTSFVTRPEISLVSYDGIRSELESYRCPGFVVRRKSLVLKDYVRPKPLYEPHYVRVHERKMALDVLSVSIGTEVKHSGNSDKVWTDFRPTASLEQITLWDLDSNLMIRPVNVTGLPFTASHDIYLGMEFKVYVGTLTLATIKIPRVPTTKLVWKREFFTFDLYMKDMPPSAILSVRVYSMKTTKMKEEIELGWVNISLSDWRDELRQGQIKLNLWGPEPSANRSRIGHNGAKIGTSLSVTVEISSHGRRVKMPNEAQYKYLVDHRISWSDTVEIVGDDYEACIGDPGYKKLQDLVKKHESGVILDDSEQRHVWSWRNYIQKQEPDLLVVLSELRIVWTDRENFSELYVMLETWKAPSVAAALTLLGKRCTDRVIRKFAVNKLNDQLSQFNVHLFLLPLIQALKYEPRAYSEVGMMLLTRALSSYRIGHRLFWLLRSEICRLKDCATNNEEYRRISLLMEAYLRGNEEHIKGIIRQVDMVDELTRISSLVKGLSKEAAREKLRDQLRTISHKMESIDSPLDPVYKFGEMVIEKAIVLGSAKQPLRLVWKNKNPKSDLHLPFCEVIFKNGDDLRQDMLVLQVLEVMDTIWKAANIDCCLSPYGVLPMGEMIGIIEVVPNCKTIFEIQHKAGLVNTAARSVDSNFMNKWIRKQCGFVDEKKKYKKGGGPTVDSAQATKKYFESVDRFLYSCVGYSVATYIMGIKDRHSDNLMLTEDGKYFHIDFGHILGHGKTKLGIQRDRQPFILTEQFLTIIRSGKPVDGNSHEIQKFKTLCLEAYEVMWNNLKYKFQKTLCCKGETKEKARKFFAGVYEEAFNGSWSTKTNWLFHAMKHY
The following text describes a protein:
Function:
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the first dolichyl beta-D-mannosyl phosphate derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-dolichol to produce Man(6)GlcNAc(2)-PP-dolichol.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MKTSNPFKRHDNSQDDHDAGHQTSHDSKGSNKDCDTAKNSSAEKEPETAWKWIKRNLSAKGIVSLFLLSLLVGEALLTMAIIARVKYTEIDWQTYMQQVSSFMDGELDYKNLGGDTGPLVYPAGFLYVYSFLYMITAGGQYIFIAQFIFALVYLVTFFLVVLIYRRSRIFPFWAIPLLMLSRRNHSIYVLRLFNDPIAMMFMFSSILALTKRQFERASIWFSLALSIKMNILLFAPGFAWVFLFNAGIMRSIMNAGLVAITQVIIAAPFIYTAPHSYVTRAFDFGRQFLHQWTVNWRFVPEEIFVSKEFALALLVMQIATLVLFSAVVWRRHIPRYYHAPHKYFKFLDFLSDMVNELKDDVGISHQHPEDEVDYPISPDDTILILFSCNLIGIVFARSLHYQFYNWYFFTLPYLLWRSGIDIRAKLAVFFLIEWAWNVYPSSHLSSGTLALCHVIIVASLVVGHPVYDSKLKGVISKDQKTSDKKKIE
The following text describes a protein:
Function:
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Subcellular Localization:
Golgi apparatus, cis-Golgi network.
Sequence:
MSNVSPNSMNLNGSTSSTASVNDSGGGGGGGNVTSPTLSSSSASSISNSNSSSSNNLKPSTQPLSSSSTLNTPTQFSLQHSSSSSSLNNTNIDIIEHITISYQDESSIWKYIEAELPNHLPLKNISWKTKTGHTKVVEKMPIEILQYNDERVKAHYDNQNLYKKPYLYLYLVHCDDPDTYKNVVRAKIKQWVTQMTERQQEWLIVYVSLGPKRFSELTSKLTRTVFDRIKNDFNVKRDRCCQLRFLDTNNTSSGNNKDKDNDNGGGSSGTGLSTSTKQQDDLWDDFLIKMKEGIISSAEQYLTTYEDEIRKMDAKRTTPGWSYQNFFFIKEGLALIYERAQLYEDALMQYFELEVLFGDPNNRSQFDQITDEVLQPNSIHCNGNILDTSFKNYRKLIYENKISLFDFKVYLFARQSKLLFLLQKPIEAATKSISFITSMSMIIKQYPNSFAPMFKESWIFSTSMELIKACQDSFDKIVNGAQQQQQQQQQQLQLQQQLQQQQQQQTINGSAQKVVKSISSTTPISKLFGAFGPFGSSSSNTPSSTSATTAANGKNTPMPSNSGIASLSAGGSTIIAGLSGSQSLNNLQSAQLSGALNTQHYIRTPSLNLTSDLSERLTEKQDRESLDFLVGDLLFSSAQRLEELAIIIGYLPVDDYNSEMFFQNVEEVIFKSVENKKIEVDSMTAFSYQPLQVSLQSSKQFTQLYFELLGQIEKLYIQSNRMRSISRLTFAIANLNFKLKEFQIAENLFKSISNLYSREHWSYIEYAVKTRLSYCQKQLGHLVDYVTTCVGLLAPGLLTNRFEKDHYLSEIIQISRKPELNIVQPMIPLFKCKVTFKETVYRYFETIKINVRIKSNLISPIRFNNGAVSFVKSGFGDKLVFQLNDFLVEPGVNNFQFTAVGTTKATFVKDSIWLKIDNLSFGYSLRNADTAIGGGGGGTNTTTTTLPGEIKVIDSESQITLESFANSPLLFYSIQYVGIKLHTHSDTIEAGVLTFTSPTGATIIPTSSVIIIQSDDKTCETSSRTINLINDKLPLSQIGYNQTLEFYLPLMAVNTDTCTHQIRIELQHQKQTKEKFSSSLVSSILFINPLTIDESVINVNNRLFLKTIIQCNSPNMIQFNSYSLEGCDSEYQSPEQQQLQQQLQQQQQLSLSSSSSSISSISSKSSQQPNLYYLVKDHNHSLAPNLNLYPGQLVSLIFEIKKYENESLSSSTSPSSATDSSNSNGNNNNNNNNNNHSKNDLKLKIKYTSKMPQQDLDRPLIRECKSLWRDQNEFSWPIKIELPTYLYQIDLSIQSRAYVGTIVLFEIEITNLKQQQQQQKESNNDNGNEKQQKQQQLQYHIVADSQIWMISGKSKHTFSFNSDTVGEKLKFSCGLIPISSGSLPIPKVTLVGINNSNISYPKTKNEKIFVYPSPQIYSCHQLQDNNNNNNNSINSQTSTNKT
The following text describes a protein:
Function:
Putative phospholipase.
Subcellular Localization:
Secreted.
Sequence:
MFVLALISLVSASTYYSVLHKSEGIYKVVPGRFADACAVGYYDDTIQTTGWGQLYIRSNFKLAETEQSYCSGYLEAYLTHHYMYLYWTNYKANEYENGQPSNTLINKMQEQLDFFKTESSTNTNEYWRRQKVIKYQFNGLVDGYMAASPAEEELPEIELYMLLSVGDLENLNEIYKTGKEPETSIVYMRKAFPDRIYHECSALVRAVGDEVYFAHGTWRGYYAMLRIYKVYDLFYGGRRLKMSFSSSPGLIHSKDDYYTVSAEDTQLFVSETTNSVYNSSVYEDINDKLLSWQRILSGLYYEKTAKEFVELIKDYNSGTYNNQWIVFDVNSWKKNKAESLFICEQMPGLMKSHDVTEYLTSEEKQNMWPSYNVPFDKEIYSKSGYPTDHDEYTSCSRAKIFNRDVKNVQTIEDMKHIMLYNDYQNDEFSKNDPKESIASRYDLRVDRPNAFGAIDAKIVSTSNPHLTYAISGPTHQGQPVFEWTQQFKNVHVGVPEKFDFDWVEINDKQ
The following text describes a protein:
Function:
May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MKGLGDSRPRHLSDSLDPPHEPLFAGTDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSLEGTAGKVGGNGSKKGGMEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEAGAFRSSGPASGLMTLGRQAERSQPRYFMHAYNTISGHMLKTTKNNTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRETDAAAEGPIPCRRMRSGSYIKAMGDEDSDESGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMLLPSKCPSWEEDYTPVSDSLNDSSCISQIFGQASLIPQLFGHEQQVREAELSDQYEAACESACSEAESTAAETLDLPLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSVPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTPHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWLETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGLCEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKPAVSRDKASDASDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL
The following text describes a protein:
Function:
Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MGSSFSGSTEFSAPAPPTVSTAVPANPPAKSAVPASPARDPELKTCWSCRVLSGSTLFGAGTYVYLVARRPLKQGIPPGPGTVLQMVIGISIACWGVVVLVDPKGKSHPVI
The following text describes a protein:
Function:
Functions as a two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Domain:
Histidine-containing phosphotransfer domain (HPt) contains an active histidine that mediates the phosphotransfer.
Sequence:
MDALVAQLQMQYRNYTVSLYQQGFLDDQFTELKKLQDDASPDFVAEVLSLFFEDCVKLIGNMARALDQTGTVDFSQVGASVHQLKGSSSSVGAKRVKGLCVTFKEYCEANNYEGCVRCLQQVDIEYKALQTKLQDMFNLEKQIIQAGGKVPQVDIN