lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). Cooperates with dynein in organizing spindle assembly during cell division.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Domain:
Composed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins, vesicles and membranous organelles.
Sequence:
MDNNNNNNNNNNDKNDKNELNKIKVAIRVRPLNSRELGIDQKIPWSISKDTISLSQNPNINFTYDYVFGIDSNTIDVYNAIAKSIVNSSLNGINGTIFAYGQTSSGKTFSMRGTESIPGIIKLSIKDIFKSIEDSILEKDYLLKVSYLEIYNEEIKDLLNPTISNKKKLKIHEDIYKGVVVANLKEEIVISPDQIFALMNFGEERRHIGSTMMNDSSSRSHTIFRMQIQSTCKQNGTIQMSTLTLVDLAGSERVSSTGAEGVRLKEGTHINKSLMTLSKVISKLSEEKTQQHVPYRDSKLTRILQPSLGGNSKTAILCTITPATTHQEESISTLQFAKRAKRVKTNYKINQVADANTMLKKYESEILELQNQLVKSEEINSLLRNTISTQEISSNNFKLGMKRFNDAIIGGSLINENKKKKKRRNTLDPSYLLKDKIIKKKIRKSENQKIKKIKNSENNISSSSSNSSGEEDDDDKDDENNYSINQDDKDDSNYEDDDDEDEDDDEESDTDNEDDEDNDEDNDDDDDDDDEFKDNLNLIEPLDDETIKKIKDLDDSLGISGQVKVKREDLDLIYEELEENKKLIEEYESTLELLNNQLDEKEIEHKELLIIIDQWEQECTNRENQNQELLEIDQQSKQSIQQLNDKLLETKQQSKQSIDQLNLQLIDIESESSKNKKSFENVLGVFEKSYRLAERLEDKYFTKEIESKKQIETLANSYLQLETTYQQQLNINQQSQQKIQSLNNDIEQFKLVWVPLKDQVNGYFQENQMFKQYIIELEEKYNTLIDLQKEVEQNYLTNTLEQQRNDQYQIEINQLTTEYNNQIQQLESTNQKLQTQLYNLLANATQSTQTLEQQLQTSKQEIDTLTNEIEQLKNQYDIIRVDNDNLSKESLELKQILLSKTQQLEEQLSLAQQQKGNIEIIQQLESIIVDNQQSIDQLKIEFDQSQQDNQSIKQSYNQLESTLTLAQSENQRLLTENKQFITSLNEIKSLFNSIQQQKETIQLEFNQRLQSWSLDSEKYKEIISTLEQSNQKSIESYESKSLEFQEKENQFDSLLTNYNQLFSKYNDLATSNESNRLEFDQFKKDSNQSIQSLESLERSLKSENDNLLQQSNLLKSQLESIEKQKQDQLIPIQLELESKKCELSKLSSQFSEQTKQVTQLLISVDQYKISTNKLESQISDRNEEINNLKLKAIEINALKEENISLKDQLTKLKKAPKSQTDREKDMIKKELEKLREKFNAIDAKLKQAIQDKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKTHLAADVKSKDFIALNKSVEILTKSQEQLKSTIIELESDLSKKNIELEKKQEELVTLNQDKLEKEKKTNQLESDHSSATIKLENYENQITQLTSEIIDLKSKFQEFKSESESNIKQQEINLKESNDLNQQLTNDKFELTKQLSDLKVEFDKSKQLWSTRSSESNDTIKELQESIISKDKERQLTSEQLVKLTDQINLKTWEYNDLNSQCQQLTKTLQNVKSSNEQQEQSIVSLESQTSAKIKSLELEISQIQENHRLEVLELNRCKNQLSEKQTLMEQDNIQLNERIIQLLHQKTKHENEILSMESNIIDLENQTKELKSKIETAQQDFEIEKNYHTGLNETNTTTIKTMNEELTRSNQTIQQLLFKISKLEQTSLQTQQQQELQQATISAQQQKQQQLADDQEKQQLYQKIKLIEKELESTKQKNLYITEQFTLKESEYLDTITDYVCKEKEFEKSKASLKTSATKIQALNDIIKKLQEEKPQQQPVVKVSSSQVVNQNGQPIKSILKKPKLVIIPREQLQQPPQFKELTLSTLNSNDSNCEPESVSASSTLTSLQSISKYIGKRSEQTTLEHDLTSSTLNLPLQQQNKKVRLVITKNNKTSTDNLTTTSTSLKSKSSSNGENKENQNNNIIIKNN
The following text describes a protein:
Function:
Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Only accepts the alpha-anomer of D-ribose 1,5-bisphosphate as substrate, being inactive on the beta-anomer. Displays a strict substrate specificity, since other phosphorylated sugars such as R5P, ribose, G16P, G6P, G1P, FBP, F6P, and PRPP, are not substrates. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
Miscellaneous:
MISCELLANEOUS: Reaction proceeds via a cis-phosphoenolate intermediate.
Sequence:
MAVVKEVLEIAEKIKNMEIRGAGKIARSAAYALQLQAEKSKATNVDEFWKEMKQAAKILFETRPTAVSLPNALRYVMHRGKIAYSSGADLEQLRFVIINAAKEFIHNSEKALERIGEFGAKRIEDGDVIMTHCHSKAAISVMKTAWEQGKDIKVIVTETRPKWQGKITAKELASYGIPVIYVVDSAARHYMKMTDKVVMGADSITVNGAVINKIGTALIALTAKEHRVWTMIAAETYKFHPETMLGQLVEIEMRDPTEVIPEDELKTWPKNIEVWNPAFDVTPPEYVDVIITERGIIPPYAAIDILREEFGWALKYTEPWED
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MGNTLKKILDLELADESQPFCCKICMEPMLLSSKKFKNQNLCVHPFCIDCIITYISVKLVDNVVEIPCPFSNCNQFLDPISWLTWCYCPNRNCSALILDECGGFATRSKCPSCKKLFCFQCKLPWHAGFQCEQSGALRDKNDVAFSKLAEGEKWQRCPKCRSFVQLSEGCRHITCRCQANFCYDCGMLFDKSHGLCACDSQLITFNRIIDLRFGNWRFLF
The following text describes a protein:
Function:
Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.
Sequence:
MLRKTGILLLLVLLTSAYELDQNESFSPRRTRVSTHSPSDVARCLNSALQVGCGAFACLENSTCDTDGMHDICKSFLYSAAKFDTQGKVFVKESLKCIANGITSKVFLTIRRCSTFQRMISEVQEECYSKLDICGVAKLNPDAISEVAQLPSHFPNRYYSKLLQSLMECDDETVSLVRSSLVSRLGPEMAMLFQLLQSKPCPSSSSLSSPAGAEGRGNWRWPIGPHVFKMQPNLRREPSTLFSKKRSADDSS
The following text describes a protein:
Function:
Putative oxidoreductase that negatively regulates the retrieval of cargo from late endosomes to the Golgi. Regulates YIF1 and KEX2 localization. Required for fast DNA replication.
Miscellaneous:
MISCELLANEOUS: Present with 5240 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Late endosome. Note=The recruitment from the cytoplasm to endosomal structures is facilitated by BTN2.
Sequence:
MGEDFMHPPFQTYPSKNSEGKKHIVIVGGGIIGCCTAYYLTQHPSFSPSTHHITIIESRRIAGGASGKAGGLLASWAFPHQIVPLSFQLHQELSDEYDGENNWDYRRLTTVSLEADVREEVIENYERLSKKAYNLNVPPPKKRPGYISNKFNIGDSNSSLSSSGSSLKNDSASNEEEGSDIHVSSSVPSLHSLTNERMRSHTNSASDLDSVSPVEQLRETNIHNPLPADLDWIRRELVNDWSSLGGTDTTAQLHPYKFTHFILSKAMETGAVDLLLGKVVGLKCDEMDCVHSLKYLPSVVKNRRNSRGHAENPDIKLGTIFNDENAKPIEINDIQQIVLSMGPWTSKILKDCPISGLRAHSVTIKPSEKTVSPYAILAELKVNDREFFSPEMYARKDEVYVCGEGDTLVNIPESSDDVEVVSEKCDELYHYVSKLSPTLSKGHLLRKQACFLPVLNVPTSSGPLIGETNVKDLYIASGHSCWGINNAPATGKLMAEILLDGEATSAEISSLDPKLYFDATILS
The following text describes a protein:
Function:
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.
Subcellular Localization:
Golgi apparatus membrane; Lipid-anchor.
Sequence:
MAESGYHSRIAQVHSDRVVTKFPEAFCKAARVDQKYDFDPRIRQSCSSERINNVSLKICKMIIIGDVSVGKTSLVNRFCKKAFDKDYKATIGVDFEVERFEILNTPFTLQMWDTAGQERFQCIAAAYYRGAHIVSIVFDLSDINTLASATKWLEAAQKENKGAGELLVFLVGTKKDLVAPQTYKEVEKEAIQVARQLNAEYWAVSAKTNEKVRDFFFRVASLSFEGTVLRELEKRQFTPVSQIGDGVSIQLNRNNPPPPRSSKTQCC
The following text describes a protein:
Function:
Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MLNFRALLFILGLFLSMLTAFMFAPMLVAVVNGEETVGSFMLSALATGICASLCLHNGQSKGINLNIRDMFLLTSLTWLIVSLFAAMPFTLYHGIGYTDAFFETMSGITTTGSTVLVGLDTMDHSILIWRSLLQWLGGIGFIVMAVAILPFLNVGGMRLFRTESSDWSDKAVPRTQSMAKHLFFIYILLTIICSVAYHLAGMTWFQAINHAMTTLSTGGYSTSDSSMAAFSNSAHWVGVVFMAAGGLPLLMFVQMIQQRDVKVWNDAQVKGFLFFLTFVSCSIGFWLWQTRDIALIDALRLSSFNVVSVVTTTGYGLTDYGAWGAFANIAFLFLMFVGSCSGSTSGGIKIFRFQIAGAIMREQLKQQCHPNGIFRERYNNRLITEDIVRSLITFVLLYMFVIVGLSVILVLTGLDPVTSFTGAITAVSNVGPGLGPIIGPVGNFSTLPDLAKWALSLGMLLGRLEILTVAVLFHPSFWKY
The following text describes a protein:
Function:
Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, such as RGS7 and RGS9, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation. Increases RGS7 GTPase-activating protein (GAP) activity, thereby regulating mood and cognition. Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors. May play an important role in neuronal signaling, including in the parasympathetic, but not sympathetic, control of heart rate.
Sequence:
MCDQTFLVNVFGSCDKCFKQRALRPVFKKSQQLSYCSVCAEIMATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCIQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA
The following text describes a protein:
Function:
Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Secreted.
Sequence:
MRILKRFLACIQLLCVCRLDWANGYYRQQRKLVEEIGWSYTGALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSLENTFIHNTGKTVEINLTNDYRVSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPLEMQIYCFDADRFSSFEEAVKGKGKLRALSILFEVGTEENLDFKAIIDGVESVSRFGKQAALDPFILLNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQQSGYVMLMDYLQNNFREQQYKFSRQVFSSYTGKEEIHEAVCSSEPENVQADPENYTSLLVTWERPRVVYDTMIEKFAVLYQQLDGEDQTKHEFLTDGYQDLGAILNNLLPNMSYVLQIVAICTNGLYGKYSDQLIVDMPTDNPELDLFPELIGTEEIIKEEEEGKDIEEGAIVNPGRDSATNQIRKKEPQISTTTHYNRIGTKYNEAKTNRSPTRGSEFSGKGDVPNTSLNSTSQPVTKLATEKDISLTSQTVTELPPHTVEGTSASLNDGSKTVLRSPHMNLSGTAESLNTVSITEYEEESLLTSFKLDTGAEDSSGSSPATSAIPFISENISQGYIFSSENPETITYDVLIPESARNASEDSTSSGSEESLKDPSMEGNVWFPSSTDVTAQPDVGSGRESFLQTNYTEIRVDESEKTTKSFSARPVMSQGPSVTDLEMPHYSTFAYFPTEVTPHAFTPSSRQQDLVSTVNVVHSQTTQPVYNGETPLQPSYSSEVFPLVTPLLLDNQILNTTPAASSSDSALHATPVFPSVDVSFESILSSYDGAPLLPFSSASFSSELFRHLHTVSQILPQVTSATESDKVPLHASLPVAGGDLLLEPSLAQYSDVLSTTHAASETLEFGSESGVLYKTLMFSQVEPPSSDAMMHARSSGPEPSYALSDNEGSQHIFTVSYSSAIPVHDSVGVTYQGSLFSGPSHIPIPKSSLITPTASLLQPTHALSGDGEWSGASSDSEFLLPDTDGLTALNISSPVSVAEFTYTTSVFGDDNKALSKSEIIYGNETELQIPSFNEMVYPSESTVMPNMYDNVNKLNASLQETSVSISSTKGMFPGSLAHTTTKVFDHEISQVPENNFSVQPTHTVSQASGDTSLKPVLSANSEPASSDPASSEMLSPSTQILFYETSASFSTEVLLQPSFQASDVDTLLKTVLPAVPSDPILVETPKVDKINSTMLHLIVSNSASSENMLHSTSVPVFDVSPTSHMHSASLQGLTISYANEKYEPVLLKSESSHQVVPSLYSNDELFQTANLEINQAHPPKGRHVFATPVLSIDEPLNTLINKLIHSDEILTSTKSSVTGKVFAGIPTVASDTFVSTDHSVPIGNGHVAITAVSPNRDGSVTSTKLLFPSKATSELSHSAKSGAGLVGGGEDGDTDDDDGDDDDDRDSDGLSIHKCMSCSSYRESQEKVMNDSDTHENSLMDQNNPISYSLSENSEEDNRVTSVSSDSQTGMDRSPGKSPSANGLSQKHNDGKEENDIQTGSALLPLSPESKAWAVLTSDEESGSGQGTSDSLNENETSTDFSFADTNEKDAEGILAAGDSEITPGFPQSPTPSVTSENSEVFHVSEAEASNSSHESRIGLAEGLESEKKAVIPLVIVSALTFICLVVLVGILIYWRKCFQTAHFYLEDSTSPRVISTPPTPIFPISDDVGAIPIKHFPKHVADLHASSGFTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQLAEKDGKLTDYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPADGSEEYGNFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLPVLTFVRKAAYAKRHAVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVLDSHIHAYVNALLIPGPAGKTKLEKQFQLLSQSNIQQSDYSAALKQCNREKNRTSSIIPVERSRVGISSLSGEGTDYINASYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFVYWPNKDEPINCESFKVTLMAEEHKCLSNEEKLIIQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISVIKEEAANRDGPMIVHDEHGGVTAGTFCALTTLMHQLEKENSVDVYQVAKMINLMRPGVFADIEQYQFLYKVILSLVSTRQEENPSTSLDSNGAALPDGNIAESLESLV
The following text describes a protein:
Function:
Involved in the initial oxidation of aniline to catechol by the release of its amino group. Catalyzes the ATP-dependent ligation of L-glutamate to aniline to yield gamma-glutamylanilide (gamma-GA). AtdA1 has a broad substrate range and is able to convert the following anilines, including chlorinated and methylated forms of aniline: aniline (100%), o-chloroaniline (92%), m-chloroaniline (69%), p-chloroaniline (92%), o-methylaniline (40%), m-methylaniline (27%) and p-methylaniline (45%).
Sequence:
MSEKLDFITKNNLWTDKQRDAADKVLAEIDSLGLEMIRLSWADQYGLLRGKALSVAALKAAFSEGSEVTMAPFSFNLVSEWVFNPFTAGGGFGIDEFDELGGVPSVVMVPDPTTFKVLPWADKTGWMLADLHWKSGEPFPLCPRGIMKKAVKSLSDEGYLFKCGIELEWYLTKIVDRSLSPESLGAPGVQPDAIQVQPVAQGYSYLLEYHLDQVDDIMSKVRKGLLELNLPLRSIEDELAPSQMETTFDVMEGLEAADAALLIKSAIKQICSRHGYHATFMCKPAINGFSVASGWHMHQSLVDKDTRKNLFIPSEGEVVSPLGRAYAGGLLANGSAASSFTTPTVNGYRRRQPHSLAPDRRAWAKENKAAMVRVISATGDPASRIENRIGEPGANPYLYMASQIVSGLDGIKIKRDPGGLQGAPYGAQVPMLPTALAEALDALEHDSELFRSCFGDTFIKYWLQLRRSEWARFLDAEGAEAAEPTGAVTQWEQKEYFNLL
The following text describes a protein:
Function:
Regulates chitin deposition in the cell wall.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Domain:
Transmembrane domain is required, and the cytoplasmic region conserved between RCR1 and RCR2 is also essential, to endow resistance to Congo red; The PY motif is recognized directly by the WW domains of RSP5.
Sequence:
MGLISYENEAINEVKKADNHHVSKFVTSYYGPSSSSWQSGIWILFVLFVAAVILIILFTFVANRRRRRMGRAPIRGTAWLTPPSYRQSQQQYTGTVQQRTDDYVPEYTETANEHDLGYYDQRGEFHPNDKAAYVAPPPLVQECSSESVNSLERPPAAVVHQANSLDTDYGLTRPSNGRVPAVSDTVEQLERLPGGTTTQEINPPERAKVNARS
The following text describes a protein:
Function:
Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate (By similarity).
Subcellular Localization:
Mitochondrion matrix. Cytoplasm.
Sequence:
MTTDMDLEQLEYEKEVEEIEKWWATPKQSQIKRPYTASTVAVLSEVTKAYYPSSQQALKLYDLLREHRNKGTATLTYGVVDPVLASQASKAGLETIFVSGCLCGLSSVDEPGMDHADYPWDTVPKAVDRIFRSQNWHARRQKQFHLMKPAEERKQLPKYDYLLPIIADGDMGFGSVTSTMKMTKRFVESGVAMIHLDDLAIGLKRFTVGQGRTVVPTSEYLRRLTAVRLQFDIMKAETMLLCRCDTDHAEFITSVVDPRDHAYVLGATTKIESLIKALKDAESTGVSMKKARENWIERAKLMTFDEAVKSTATPKEYENYISAISKKPFHSISERQELAEKYLSNEVFFDWELPRSSDGQYFFKPTVQTVIERAIAAAPLGEMTWARMDYPKWQDIKAFHEGVRAVYPDRMFAFGFTGNYDFKAAGFSEEQLRNLTSDMAKLGVCWQVQPYFTCQVLNKASVDYSNIWKKDGIFGYVKTVQEPALKEDVDGFENEWCGTYFADKLLSAAGSSDKTIPY
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Is involved in resistance to the arginine analog canavanine (CAN).
Sequence:
MGKKAKKKAQTKENLNQTKNLSEQPGEVAEEAVKEKQACVHLDKGLNLDKVLEKIKSSQVIKCHECKEGAKAKGSNKGKHKAIWVCLECGCYVCGGVGLPTLPQSHVLKHIRSTRHRLVIQWENPQLRWCFPCNSLLPNGEKKDALLEVVKLMKERSLNSLAPSSSDDAEGSGSITSDIKLESAAVEARDGYVVRGLVNLGNTCFFNSIMQNLLSLDQLRCHFLKDDVSGVGLPLASSLRKLFAEMKPEAGLKSVVNPRAFFATFCAKAPQFRGYDQHDSHELLRCLLDLLSTEESAWRKRRGGVCDDDEKATSATLVESVFGGETSSIVSCIECGHSSKIYEPFLDLSLPVPFKKTPPKKQQALSRAKKGKLPPKRVSKNVSKVSKVSKVVLPTKAMSEPSSPGKAVVATADSDNGAVSETPSVITLDNKETSESVAQSDTVFDSFWLDVIAPETFGDETNLDMEDSVSDKTPTPEANTSVSLSDQTSEGNAERLIQDSDEFAKADEKDVQATQSDECTAASAISAEINQDSCIGLDPGLGESSSSVNPWDEEEVPLMVADSQVLYMPYKENISYNEGEASSSSFVSGDHQEPDNNDFVGLGGLFDEPEVTEGPVFGPPCKPEASSGAVGFTAFSSESDPEEIDDSDSPVSVERCLAHFTKPEILSDDNAWNCENCSKNLKLQRLREKRKSTSNGWVSENEDGVSGETDVKQDPSDSGREAMSSNDSESEGEEDSKKVIIVKRDATKRVLLNKVPPVLTIHLKRFSQDLRGRLSKLNGHVAFKEVIDLRHYMDTRCSGEDPPVYRLAGLVEHSGTMRGGHYVAYVRGGGGGKKVKESGASSSSSVWYHVSDAHVRQVSLDKVLHSEAYILFYERIV
The following text describes a protein:
Function:
tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. Adds the two cytidine residues to tRNA.
Sequence:
MLCPVSHLADLRQQVPFDLALLPPQACLVGGAVRDALLGRRREYLDWDFVVPSGAIETASAIASRYRAGFVVLDKARHIARVVFAHGTVDFAQQEGMSLEQDLARRDFTVNAIAYNFQQNKLIDPMAGVGDLQRGQLKMVAAVNLADDPLRLLRAYRQAAQLQFTLDPDTRTVLRELAPRIKTVAAERVQAEFNYLLGSPRGSQWLLAAWQDGILAHWFSHANLSSLNAIGCIDLAIAAIKNQLTLVERQQFFQALGKKGIAIAKLASLVCADVKIAEGELQRLKYSRHELRSVQAILQGYPQLSCLENSPTVRQLYFFFVELGKYLPHFVLYALAHCPHNYHSFIFELLTHYLNSGDRLAHPQPLITGKDLIDKLHIKPSPLIGQLLTEINIAHIEGKISNEQEALAYAQELGKS
The following text describes a protein:
Function:
Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.
Subcellular Localization:
Nucleus.
Sequence:
MADQIEDVLELSHNLQDVTSELSQQIKMIDFKGVAQLPPLEQAQFYSKLAYVTNSAMFAFILASGGDPKTHPIMKDLDRVKTYMGKVAHAEGKPGPARKDERNTKVDVPAAKRIIFAQTERAISADSIKEPETTSDAAEAFLKDVTKSASKKDKKDKKDKKDKNGSKDKTEEKTQKSAKKDKAKVVKPKKAKKN
The following text describes a protein:
Function:
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
Subcellular Localization:
Nucleus.
Sequence:
MSVVSLLGVEVKNNPAPFDAPYEFEITFECLEQLQKGKIPQNEYDQELDSVLVGPLPIGVNKFVFRADPPDLSRIPNSEIIGVTVILLSCSYEDREFVRVGYYVNNEYTDEALALEPPAKPVIDKVQRQILAEKPRVTRFAIKWDSEESAPPEFPPEQPEADLNADGDQYGIEEEEEEEEEAEAAPVEGEDAAMAGGEDTAGPANDEDAESEAGSEEIDIEDSEGEDEEEEGEGEDGPEDDMEMDEGEGANGESKVPQPGAKADVMVH
The following text describes a protein:
Function:
Plays a role in autophagy. Functions at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions. Also plays a role in mitophagy and regulation of filamentous growth.
Subcellular Localization:
Preautophagosomal structure.
Sequence:
MSNPDPEPDPSYTVFIRLPFPRGDFVDPPDVEWDAAKDKALWKILSKASKNSDVDWAALATKFEVTLAFLLQQAAWLYERQLSQVRAQMRKVTVSKGSLAPSPVPGSTSETTGGEGMKRTGSGGGGPRIQSSLSNRKETSLSKTDGSVPDTPNRAMAPRVSRTSSRDTTIQSRTFSPTSPRPSHATIERRALSPKPRSRPASMAIDHPTRNSPQQAQLSSPEDSSDDDAFQFQSRLLYRRFPSSKKKTQGPSSDDDEPAFLRTSHDPSATLRGDPRNISRRTPVLTKKPIPIESQTSDSSTSSTAQIVNKRHDAVSGGGRRPPSGPLSPRRTAELQSERSDGGTPSMGSSFSDLDDASVTQSALEEALASNMQAGGMASRMSTISQALRSRYL
The following text describes a protein:
Function:
Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.
Subcellular Localization:
Periplasm.
Sequence:
MYRLIVALLLGIVTLTACAQPSQPSSNKTSTTPTNATPANVQQRVTAALNTLDPDFKPDYIGAAPFPGFREVVVSGQILYVSDNGRYLIQAQPYDIQNKKFAVSEGLLSYRRTQLATVPQSQRIVFAPKNPQYTISVFTDIECGYCRKLHSEIAELNKQGIAVEYLAFPRMGLGSQDYKDMVSVWCAADRKQVLTEAKAGKQIQNKNCNNPVALEYSLGQRIGVNGTPAIFAPDGTQLGGYLPPEKLRALLDKLAAATAKGG
The following text describes a protein:
Function:
Catalyzes both oxygenative decarboxylation and oxidative deamination, depending on the substrate used. Has high activity for L-Phe and L-Tyr, but relatively low activities for L-Met and L-Trp. L-Phe is mainly oxygenated and L-Met is mainly oxidized.
Sequence:
MGVTVIPRLLGLKDEKKIATTVGEARLSGINYRHPDSALVSYPVAAAAPLGRLPAGNYRIAIVGGGAGGIAALYELGRLAATLPAGSGIDVQIYEADPDSFLHDRPGIKAIKVRGLKAGRVSAALVHNGDPASGDTIYEVGAMRFPEIAGLTWHYASAAFGDAAPIKVFPNPGKVPTEFVFGNRVDRYVGSDPKDWEDPDSPTLKVLGVVAGGLVGNPQGENVAMYPIANVDPAKIAAILNAATPPADALERIQTKYWPEFIAQYDGLTLGAAVREIVTVAFEKGTLPPVDGVLDVDESISYYVELFGRFGFGTGGFKPLYNISLVEMMRLILWDYSNEYTLPVTENVEFIRNLFLKAQNVGAGKLVVQVRQERVANACHSGTASARAQLLSYDSHNAVHSEAYDFVILAVPHDQLTPIVSRSGFEHAASQNLGDAGLGLETHTYNQVYPPLLLSDSSPAANARIVTAIGQLHMARSSKVFATVKTAALDQPWVPQWRGEPIKAVVSDSGLAASYVVPSPIVEDGQAPEYSSLLASYTWEDDSTRLRHDFGLYPQNPATETGTADGMYRTMVNRAYRYVKYAGASNAQPWWFYQLLAEARTADRFVFDWTTNKTAGGFKLDMTGDHHQSNLCFRYHTHALAASLDNRFFIASDSYSHLGGWLEGAFMSALNAVAGLIVRANRGDVSALSTEARPLVIGLRPVVKVPAAELATSQ
The following text describes a protein:
Function:
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
Sequence:
MQHPDSILTLLKKSEEFLKKKEIPSARLDAEILLADLLNLQRVKLYVNFERLLNETEKNAYRERILERSKNKPTAYITSQKAFYNSIFFVNENVLIPRPETEELVEKVLSDFKGNIGEQNVLDLCTGSGCIGISLKLARKDWNITLSDISKEALEVATKNAIQILGEEKHIQFLESDLFLSIPKESKFNLIVTNPPYIPISDKAEMMKDVIDYEPHLALFLENPKDFLSTLIAQAYERLVEGGKLYMEILPSLSETIISDSIAKGWENGKIEKDLSGKERFVILTR
The following text describes a protein:
Function:
Pre-60S-associated factor involved in the cytoplasmic maturation of the 60S subunit. Involved in the dissociation and recycling of other late pre-60S factors before newly synthesized large ribosomal subunits enter translation (By similarity). Can complement the growth defect of a yeast mutant lacking REI1. Required for leaf growth under cold temperature conditions.
Subcellular Localization:
Cytoplasm.
Sequence:
MSGLACNSCNKDFEDDAEQKFHYKSEWHRYNLKRKIAGVPGVTEALFEARQAAIAQEKVKAVEAPMLYSCGICNKGYRSSKAHEQHLKSKSHVLKASTSTGEEDKAIIKQLPPRRVEKNNTAQLKGSIEEEESEDEWIEVDSDEDLDAEMNEDGEEEDMDEDGIEFELDPACCLMCDKKHKTIEKCMVHMHKFHGFFIPDIEYLKDPKGFLTYLGLKVKRDFVCLYCNELCHPFSSLEAVRKHMDAKGHCKVHYGDGGDEEDAELEEFYDYSSSYVNGDENQMVVSGESVNTVELFGGSELVITKRTDNKVTSRTLGSREFMRYYKQKPAPSSQKHIVNSLTSRYKMMGLATVQSKEAIVRMKVMREMNKRGAKSSVRLGMKSNVIRNLPNNVTY
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport; Acts both as a kinase and as a phosphatase on BglG.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Domain:
The EIIB domain is phosphorylated by phospho-EIIA on a cysteinyl or histidyl residue, depending on the transported sugar. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the EIIC domain; The EIIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; The EIIA domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the EIIB domain.
Sequence:
MTELARKIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLKKTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGLDEKAQQAPENDDKGNLLNRFVYVISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFWFFPIILGYTAGKRFGGNPFTAMVIGGALVHPLILTAFENGQKADALGLDFLGIPVTLLNYSSSVIPIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPVTFLLVGPLSTWISELIAAGYLWLYQAVPAFAGAVMGGFWQIFVMFGLHWGLVPLCINNFTVLGYDTMIPLLMPAIMAQVGAALGVFLCERDAQKKVVAGSAALTSLFGITEPAVYGVNLPRKYPFVIACISGALGATIIGYAQTKVYSFGLPSIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMLHFITAKRQPAQGAPQEKTPEVITPPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFSAHVNVGDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQISAGEPLLSIIR
The following text describes a protein:
Function:
Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Subcellular Localization:
Mitochondrion.
Sequence:
MRPGVAAVAAVRIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRRIAEFAFEYARDMANPTALLLSAVMMLRCSDFTEEICRR
The following text describes a protein:
Function:
Copper ion-sensing transcription factor which activates transcription of the CTR1 copper transporter under low-copper conditions. Promotes filamentous and invasive growth.
Subcellular Localization:
Nucleus.
Sequence:
MILIDDIKYACMECVRGHRSSSCKHHERPLLQVRSKGRPGVYANGNPNHRVAIFAEEIAKSDKPSTNGTKRCKSEPIIVLKASSKQVIDCSSGVIIGPYDETKTKPSTVEKRTPSPPIISDESFINTSACCTPKISKGKSCGCCNNKRKAVNKSKILQNYIKNKLNQKINNNETLVFMNKSHTTNNEQKEDHQLYGMVPVPSCSIPGTCCCDDACSCQGCVVHGNSKYQIPLPTSKQQVTDTTNPFENEEKFIFNSMPQTDKSDLFFNTISTSSNVPPADSSSECSCPPNACDCTNCETHGILNGFRLDDYFKDQSKLMNVLDFNFSELLGTIPEQPIPTEFMQPPSENTLLTSLSSENSFIPNQTKELSTQPPILPLDAQNVCNELDQLEPLVPSLQPCDKKATKWVNNRDTLEDVSDNRVKSCCSKKTK
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MSNPSKLSISPPNTFQHVGGSNLHVNKPPALQSPPRSPPLQHTTAQNNLAKSTSASNIAGIANQTTPSSSGSSSGSSSLNSIGSLTKSTSNSNLNINHYSSGNATMGASLQSTNTGNTITQSSSPPSSSSSTNNNNNVLPLPNKILHHPSPKKTTKSTIISGKLKRFFKSRPSRDSLYEKHILSAPFSSATLSFINIFKIITALKKTNAIETEGLFRVNGNAESVRSLWLMLNNVQEAIPVDGNSSAHDLAGLLKLYLRESKFPLVPLELFTSPAVPATIDEARVFVEEKLPTENVRVLSYLIEYLEQVSLKSSINKMNPIGLGVCFAPNILRSVNTNPSNPQFQVHMTNIQSHCNFITLLIENRLKIFKDSALSPVQGSNDDEILENLIIQSPDDELFDEQHQHEQELIDSSHEHHHSINNGDNNNNVDTSNVNGGSGDENNQSNVINDTALYDEFISLLTDESLGSSQKSVIIQRMTTLFQTDGDRFKSFLRDMQIDGIISLLEYILTLDEN