lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probably involved in repair of photodamaged photosystem II (PSII).
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with PSII on the lumenal side of the thylakoid membrane.
Sequence:
MASASATATLLKPNLPPHKPTIIASSVSPPLPPPRRNHLLRRDFLSLAATSTLLTQSIQFLAPAPVSAAEDEEYIKDTSAVISKVRSTLSMQKTDPNVADAVAELREASNSWVAKYRKEKALLGKASFRDIYSALNAVSGHYVSFGPTAPIPAKRKARILEEMETAEKALTRGR
The following text describes a protein:
Function:
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. Required for the regulation of the lsr operon and many other genes.
Subcellular Localization:
Cytoplasm.
Sequence:
MARLFTLSESKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWRHLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIAPEYIAAVSACSMREGIVLYNNEGAPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSDIYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADILSPVKETGTLLGVVSSQAAELCGLKAGTPVVVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLIAERLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKATLFRALEENAAIVSACNLQQIADFSNIHPSSLVFAGGGSKGKLWSQILADVSGLPVNIPVVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTHTPDPEKHELYQDSRDKWQAVYQDQLGLVDHGLTTSLWKAPGL
The following text describes a protein:
Function:
Required for ciliogenesis.
Subcellular Localization:
Cell projection, cilium. Vacuole membrane; Multi-pass membrane protein.
Sequence:
MFFIRKKLRLKQTEVYVAMNETMSVFQVLLGFQMLMLLIDLIFNTLSILFFQHNTVLLTLYILQDTCLVLSLILLVITFSSTFVFQAGLISLLISRFAHTILISFFYLALCITVHVYSLRLRWDSDGVHVWNYWIGALFVIQKIFAALYYGTVKRSALNLSDPRLRADSKWLHNKVRST
The following text describes a protein:
Function:
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cytoplasm, cytoskeleton.
Sequence:
MGESSEDIDQMFSTLLGEMDLLTQSLGVDTLPPPDPNPPRAEFNYSVGFKDLNESLNALEDQDLDALMADLVADISEAEQRTIQAQKESSQNQHHSASLQASNFSGAASLGYGTNVAATGISQYEDDLPPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKEAKVKKLVVKVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENVVEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLEESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDARTLNQWVMGIRIAKYGKTLYDNYQRAVAKAGLASRWTNLGTVNAAAPAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPAMPPKAKGIGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGTAGSELPPPPPPPPPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGGEQDFMSDLMKALQKKRGNVS
The following text describes a protein:
Function:
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).
Subcellular Localization:
Secreted.
Sequence:
MSLNQKVGEFATMKNLVLLAVLFLSGTQAKYFPWQHEEPHTPAQQVREVLESYVHKVRDLGREAVSQLETSDLGKQLDLKITEKLDTFGTNAMNLRKQINPYVENIREQVSKELEKELPVIKEKIRPILEAFQKRWADDAKAYQEKISPLVAELQKQTKNNLDSLYKKITPIAEEIRDKVRVDVDSLRSRLTPYSEEVRVKLVEKLEELKANAGPRAEEYRAQLSQHIENLKEKYGPLAQSIRERLVPHAEEARNNLAKIWENLRAKLQRQGA
The following text describes a protein:
Function:
Endoplasmic reticulum-localized palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes (By similarity). Has a palmitoyltransferase activity toward NCDN and regulates NCDN association with endosome membranes through this palmitoylation (By similarity). May play a role in cell proliferation; Also has a palmitoyltransferase activity-independent function in DNA virus-triggered and CGAS-mediated innate immune response. Functions as an adapter that recruits IRF3 to STING1 to promote the activation of that key transcriptional regulator of type I interferon (IFN)-dependent immune response.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
The DHHC domain is required for palmitoyltransferase activity.
Sequence:
MDTRSGSQCSVTPEAILNNEKLVLPPRISRVNGWSLPLHYFQVVTWAVFVGLSSATFGIFIPFLPHAWKYIAYVVTGGIFSFHLVVHLIASCIDPADSNVRLMKNYSQPMPLFDRSKHAHVIQNQFCHLCKVTVNKKTKHCISCNKCVSGFDHHCKWINNCVGSRNYWFFFSTVASATAGMLCLIAILLYVLVQYLVNPGVLRTDPRYEDVKNMNTWLLFLPLFPVQVQTLIVVIIGMLVLLLDFLGLVHLGQLLIFHIYLKAKKMTTFEYLINNRKEESSKHQAVRKDPYVQMDKGVLQQGAGALGSSAQGVKAKSSLLIHKHLCHFCTSVNQDGDSTAREGDEDPCPSALGAKARNSRLICRRLCQFSTRVHPDGGSMAQEADDAPSISTLGLQQETTEPMKTDSAESED
The following text describes a protein:
Function:
Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Subcellular Localization:
Mitochondrion.
Sequence:
MYRFIAKFHFCDIRNKLFNLSLIHAINHGFNNKALQQACLDLNISSAASTVIQPIDLIHYSMRKWNREIIDTMTFDENFKQFTISNKIKNLIKQRLQLQGPYMGRWNEAMALGAQNANQTSAILWQFADDCWYLAGDKSQDYNHYTKRMMFLYIYISTELFMLTDKSPNFFMTWDFLERRMLEIKDFGSQIELISTTMKTLWNSGYYMTTMFYNFPKGTLK
The following text describes a protein:
Function:
Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDFKRQLASALVLNVVLKVFTFLLTAGVTRQLAPNENGVNFSFQLYFNTVLFLARESVRSVNARHNLREKSGSGGAALKVMNCAAISLPLGLLVVLVLELLHGFRITLFPSLAALANVGSVSAASAEAQGPGMDGGTLGLPEVVQVISVIAALSIEPCLAVAQSLDNVRTVVTSEFWALLARLTATISILWWYGSLSGHPWITRMCFSVANLSDALATVAYFLCLWNAPNQERGRKAAGGGGCEGDEDGEAATSMYQVRVIAARVLWGDTVQTKTSARSHPLRECLPWCYLSLHSMHDVLLREFRLFLQFFRESCLRLLLTEGEHFALAAMGSAAAVGQYSVVTNLGSLIVRLVFRVWETACFARWSRDIAAGRMADASVLLFVMLRVSLYFGAVAILLGPPLAELVLLRLFTRRWATAETVRALQLYCYQLPLMGWYGLLDAFVRATASPRVLRLAQQVLVVQAAVYVAFCFAALRLHWVGDPVAGLIVANGISTGLRCATSLWMIIKTPGRPQQESRRFEVQLRDFSAVFDSRIATVWFLLFGCTRMLLPFISLTTSGVVSVVLFFPLFAASVLRWDPETRVVVKALVLSSKRSGE
The following text describes a protein:
Function:
Dynamic component of the endotube in intestinal cells, interacts with intermediate filament and regulates intestinal lumen morphology.
Subcellular Localization:
Cell junction. Cytoplasm, cytoskeleton. Note=In the intestine, localizes subapically and at cell junctions, indicating localization to the endotube. Interacts with intermediate filament (IF) proteins and localizes to the IF network in an IF-dependent manner.
Sequence:
MVVEQKEQEPIVKMRDRNVNAAAHSALARGIEALNEGEVTEETEEIRKLDTQLDHLNDYMSKMEERLKAHNDRMMETLKQQKEEREKRRRSFHERMSQNQSEDEEFKKQMSSILKRVQSVKRTEK
The following text describes a protein:
Function:
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs (Probable). Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core) (By similarity). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP (By similarity). To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate (By similarity). Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSEITEGDLQKFHDEHFNAKAVNLWNVAFAQNDRGGNSESANVEYTQSVERYPDGTIRTLTDEQILWFRESEKRELMWKKEKEQLLKEKELRQKALDKERMVSSKPETNPKTPISLKELKDIEIYQNQFHYSAYEILEEEKILDNIFRKFTALPIKYWPATPIRG
The following text describes a protein:
Function:
Fusion of the shell and cargo protein of a type 1 encapsulin nanocompartment. Protein missing its signal peptide makes 33 nm particles in E.coli (called cEnc), protein missing its signal peptide and diheme domain (residues 1-86, called Enc) makes 29 nm particles. The cEnc nancompartment encloses c-type heme. The cargo protein NIR-HAO (AC P0DV45) is probably targeted to the nanocompartment by its association with the diheme domain in cEnc; removal of the diheme domain in Enc halves the amount of cargo.
Miscellaneous:
MISCELLANEOUS: In the signal peptide was removed prior to generating the constructs for expression in E.coli.
Subcellular Localization:
Encapsulin nanocompartment. Note=This type 1 encapsulin nanocompartment may be targeted to the anammoxosome.
Sequence:
MVMGILNTFKKVYAVTGFFALLAVFSLSQVGSSAFAACAKVDDCFSCHTTQELNAVHKNTPYQGQSCIVCHKAFAADDTCSDAKDGRFAKISSEININKEDWNKIQRAVHETTEKHLVGRKFLNIYGPLGTGAQSVPLDTYGLPSWASIDMLGEGNEAIHPLKREIAQIYLIYKDFWLFRRDIEFSKKCETPIDISAAIGAAVSVSRKEDDMVFNGLSEMGIPGLLTASGRNIMKLSDWSVIGNGFQDVVLAVEKLTSRGFNGPFALVVSPKLYAYLHRVYERTGQLEIQGVKELVNGGVYQSYVFNKDVALVIATGSLNMDLAVGSNYKVEYWGPQDLNHRFRVVGSSVLRIKCPQAICTLE
The following text describes a protein:
Function:
Involved in tRNA methylation. Facilitates the recognition and targeting of tRNA(Arg)(CCU) and tRNA(Arg)(UCU) substrates for N(3)-methylcytidine modification by METTL2.
Sequence:
MATGRLGVGETLEALNAAVGPGSPVWFKETHARHLRVRDFLAPRSALQARFRDGQVPECVFRAVSCLQGPGVAPVLRCAPTPAGLSLQLQRPAVFEHVLGALASYATPAKPASPGPRVVLHCPALRCNSGTLRLSQLRAVLVADHLVRVLRAHGVRVCSVPPVRDPHMSTFLQKLRVEWPTASKSTSTETLRTCVLANLNGSKEATLPPGVLGRLCLKELVEQRGTAGYDPSIDHCLVTEDVLSVLSELQEAVRHWPEGGHPGPAGRPDAGVDDCVVIHVVSCEEAFQQQKLDLLWQKLDDRAPHKQKHLVCGPVKMAGVPGTQLTAPQYYRLRHAQVCEASALKHGGDLAQDPAWTETFDILSVATIKFEMLSTAPQSQLLLAHSTISTKGTKSGTFVMYNCARLATLFEGYKHGTEQGLYPTFPLVSSLDFSLLHDEGEWLLLFNSVLPFLDLLSQTVSLAGTPGLHIPVRTEMVCKFLVQLSMDFSSYYNRVHILGEPRPHLFGQMFARLQLLRAVREVFHTGLAMLGLPPLSHI
The following text describes a protein:
Function:
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
Subcellular Localization:
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MLMTQTPVSLLQGQNTTSSYNTQSQKTSYDRRDPAAADSSHATTLVDPNDSSFFFATDPVSSMNGVVGTAPAGTMYVRALYDYEADDRTSLSFHEGDIIQVITQLESGWWDGVINGVRGWFPSNYCEVIASPDDAPGETEEKANPEQVVEEEAEDHDVYHESFDEDDASDRDDDPDSLPIEGTDGDRSRADFWIPQATPLGHLFYYNTMTGESSNELPLESPASVNETGPRDRMNVTIPDRTRPPPEMMARGLTQDEEDEDDITSASEVEGETFMTASRGSLPKNRRLYDGVSPSTSMDSINGQPSGNRGRTETYFNSNHHIVPMTSTTAFTSATFNLPTAATIPRSFFDDGSMQPLTWSRLVANMKKAIDRYREAIKNNHRSEYVARAEDISDHLRLLLAAGSGTTDNHSGQPSIISTNKALYPHFRDMMSKFSKLVISSHIAAADWPNAESVQKCLQEADGVLMGVYSYVEVARQQRGEDIPRLFPGFVIGSTSGGSWQTNGLGPHDPITSNFLDDEEGVVEPTAILDSKLLERLDELKRMLVSGIRELDKSLVVTDKVVTPFRHEVISNNICAAGGKVVDMFKPWIATIESIDLSCLGSNGFQQPQLLDFATNKQSLYDNISDLVLGCQAVAGPLADEWSEVRGHALEERLDYVRQCARALETNSSHIGFSLQLLSEQVQMVMQQQAEARAREPMQRTPLSRGDSLPYERHLRTDSAFLRPVLMSSASFSEGDPTAPTFQRKGDPSKMKKFFGEDPTPIQPVDDTPEFLRLDYEAELSWDQKVQPPVVKGGSLLALVEQLTRHDKLDSNFNNTFLLTYKSFTSARVLFELLVKRFGIQPPEGLTQTQYEQWRDSKQKLIRFRVVNILKNWFDNFWMEDQSEETKQLILDVYNFVNETVKSTETPGSKGLMAVLEQRRSGKEVNVRRMIQTVNQNTPAPIMPKNMKKLKFLDIDVTEFARQLTIIESRLYGKIKSTECLNKTWQKKVAEGEPEPAPNVKALILHSNQMTNWVAEMILAQTDVRKRVVVIKHFVAVADKCRALNNFSTLTSIISALGTAPIARLKRTWDQIPQRVLATLETMRKLMASTKNFGEYREALHLSNPPCIPFFGVYLTDLTFIEDGIPSVLKKTNQINFAKRAKTADVIGDIQQYQNVAYSLQPVPELQEYILSNMQAAGDVHEMYDKSLQIEPREREDEKIVRVLAESGFL
The following text describes a protein:
Function:
Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Cell junction, paranodal septate junction.
Sequence:
MMHLRLFCILLAAVSGAEGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLHGISGWSPRIGDPNPWLQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSEVPPELDPWYLPPDFPYYHDEGWVAILLGFLVAFLLLGLVGMLVLFYLQNHRYKGSYHTNEPKAAHEYHPGSKPPLPTSGPAQVPTPTAAPNQAPASAPAPAPTPAPAPGPRDQNLPQILEESRSE
The following text describes a protein:
Function:
Cadherins are calcium-dependent cell adhesion proteins.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MIDIAQEGLITVAGPLNSGVQSVHNLVVSATDGGGLVSQVNANVAVSVIGTGEMPPVFSQARYSFSVPEDAARQHTVGTVMASHSDPGKTDPITYSIHSGDRQGYFAIDPTTGRIYTQLNLDHETVSSLLLNIQASSGNPPVYGRAQVNITILDINDNRPEFTVATESVAITENVSPGTIIFVASAQDQDAGSNGLVRYSLLNNQDNLFSVNSISGEVKILRSVDADDDNPLRYELKIMAHDQGTPQRFSNLTLLVIIQDENDNGPMFSPTFYDVQVPESASVNYRFLQVTALDRDSGLNEFITYYLSNSADSPNFGMFPDGWLYVKHRLDRELRDSYFLQVVARDNGSPPRNATANVRVTVTDDNDNDPRFTQESYHFSLVENLPTGTTVGTVFAVDADIGNNGDLDFSIIPNNSSFIITTGHQRGVIKTKRPLDRETTARYDLVLKVRDRGTPPRTATATLHIVVEDMNDNAPYFSHSGQYLGEVEEHQPNGTEVIRVLADDPDNGENGTITYRLVTSTPGMNGEEMFNIHSQSGLITTNAPLDREQKPTYVLSVAAVDGGTPPRERTTFVHIHVTDSNDNAPVFVNSTISIEVEEGLEAGSTIGSVHALDNDEGENGRVSYEIMQGNLYGTFGVDRNTGRIFTAKELDFELNARYRLIVQAQDNNARSQKSSTIYVNVNVIDINDNAPTFRSDPVMFGLQENTAVNSTVWTFSATDVDSGRNGAVRYRIMDQLPNGNNFRIDSVTGALQTTTPIDREQTSQFTLVVEATDQPVNLSHARTKTTTARILVEDVNDNTPVFVSRTETYVMEDEPVGYHVMYVIAVDDDFGDNGRVTYQIVSGNQGGKFLLDPNTGLLAIERRLDRETESRYVLNITATDHGTPSRSASHLITIHVRDVNDNQPRFLQDTYQASVSENQSPGTSVIQITALDADAGTNGVLTYNIPRGVAEDRFTIEEQTGVIRTAFRLDREEKDSYIVTAYARDGAYPSRFGFTSVVVSVLDTNDHAPVFKDAEYMMTVPENQPNYGVIHTVVAYDADIGTNGQVRYEIIDGNVGGKFAVDAVTGELSVISDQALDRETVPLYHLIVQAHDNTDAPRTSTTNITVAVSDENDNNPIFTDPSYQQTIQEDVSVGSTVIRVTAQDRDEGVNGEVFYFLSNETNGMFRIDNTSGIITTTRLLDREKQSVYSFDAYASDRGPFGPRTSNVRVTVDISDVNDNAPVFTQVPFETTIERNIGVNQQVVTVTAEDKDTGSNAEILYRFDSSNANSQKFNIGPQSGIITTQVSLVGDSANIFRLQVIAEDQGSPAKSSTGLVVITMSDSSMTTLRFDNGTYSAYISENAIANTDIISVSASREDGQPASVTYSFASGNDDESFEINPTSGLITVKDSTNLDFETAQRVRLIVTAQATTPSLYGYATVWVNLRDENDNAPRFDQDRYTTSVWEGNDRGMFVIQVSATDADSGTNSEVQYSIVSGNHDNAFVIDRDRGIISTNVRMDREVRDSYRLELRAVDKGTPRLTGSATLRISVVDINDNRPTFPEPYPPVNVLEGAEVGSELALVTANDIDTDPTITYTFTTHGNPGGVFSIDRYSGKVTLAQPLDRESVQSYIITIMASDEVHTDQTNVEINVLDENDNPPVFDQQTYQVDIAEMVPPHYSVATVTATDRDAGSNAEITYSMTVAPVEGFYVDPRNGTIFTNKTIEINRMQSTIQLVIEARDHGVPSLASVVAVRIQVNDINNHAPQFTAGQYEEHVSEAAPRGTTVATVTATDADQSHDNSNIHFGIVQGNEDGKFQIETIEPSPNSDQYMGKIILFQAIDREEVPMYTLRVLASDRGTPERNSTVTVYVLVDDVNDHSPIFNSTQYVAQISEEAVIGAFVVRVFAFDADSGPNADIHYEITSGNDDSLFAINSQSGVITVANPLDYDTVAQHNLTIRAKDSTSDGAKHTITSVLINLIDENDNPPDFPVLMYLEDVPEGRPVGTLVFTAEARDKDAGIYGTLSYVILDRDVTNDGTSDVAQGKDAFEIDSSTGEVRTREVFDYETQNTYGFYIRATDTGGLSTDVQVGVSIQSVDEFPPVFTQDNYIFTVIANADVGTFVGQVEATDADGGPDGIVSYSIRNDKFAINESGVITVKASLLEGNTVTDPSRRKRRQAENEDQINLIVEASSGRPGSLSEQKAISVKIDRSCPGCNPSAQSALSPLTPLSLALILIFALIAVILCVVLIVLKFKRRKQRPPPTSFDGSFDTVVVQNTHSFGRDGSQKQSQQLRMFKGHPSFATADNSADMGTLTRTDISEHSNNSQSSGRGSSEVDEDEEIRKINETPASISPNSDQHKVREIPDSGIQHDEDAMSEMSVKDTADLISRLAVTSNQGSQINTMISKSVESMHVFRDEGGGEAGGDMDIGNLIHQKLHEVGMEENEAIMDGTRDFVLIDDGQPSVAGSLSSIVASEEELRGSYNWDYLLDWGPQYQPMADVFLEIAKLKDETVAKRQIHHPKSAFTPKVRTHPPPLITNLPQSSVSTIAPIALGGSSRTSQATSISSLPRSPISHESTFTSPALTPSFSPSLSPLATRSPSVSPLVTGPNSGASTPHRRSAYSSTFMTRVPSPTGSEQELRI
The following text describes a protein:
Function:
Probably involved in mitochondrial export. Confers resistance to the anti-pneumocystis carinii drug pentamidine. May act by the removal of pentamidine, or its damage targets, from the matrix by an active-transport mechanism.
Miscellaneous:
MISCELLANEOUS: Present with 1460 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MDSRVALVRKYIAPSVIKSDSIQLHGLVKAPLFKALNSRYKLGSLQIVQDVDWNAKTTPSDSPEPLAATLNSNRSLPMTKFPKQEILEQVKLDTKVGKWRKFMTGWFRIGLYLLKSYKTGIQNTLKVFWDTRNEEQKFSIKNGALANLVREIEMHEINTRLSSSSLPTSSSAKAPLRPLSINRKTLVELIRRDQIWKLPVFFTLVFIFEEVSVLIFTFFPRVCPYNCLTPGGYKKLSNSYIKGTTSTQGNYGLGPLEFTKQGTIKYEPPYAVPIENLYNFLTSFPQSMISNWKLYIYKKLKLQKLLCNEIEKIYQYLFIDDWLLLQSILNTDVEKTKIALSDRELVNCILERKLYHMGDDLNEMVNDTLGKEILLKRLFLYWTLRYNDTISLNGKHTFSEKWGVNNISLLKYNSELVATKDIQ
The following text describes a protein:
Function:
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MGKDRKTERVSGRTRSPLGPIARSWLVFYNAANAIGWSYVLFLFVRHLLHTLPSPTWYEGVYGAVKDPLKAFLPLSFIFEVLHAATGLVPSGVVPTALQMFARVFIVWGVAHLVPKVQTTLYISLVVLPWCLCEVTRYPYYVTNVLGVKSDVLLWCRYTFFIVLYPLGAFGEVLTMYAALGPIKEGDLHLAGIPSSLQGAFQFYYYVIVVFLLGWAPCWWPIYKHMFRQREKALGSPRTKEE
The following text describes a protein:
Function:
Transcription factor involved in the induction of hypoxic gene transcription when the cells are shifted from aerobiosis to anaerobiosis. Promotes exogenous sterol uptake and stimulates endogenous sterol biosynthesis. With SUT2, positively regulates mating by repressing the expression of the mating inhibitors NCE102, PRR2 and RHO5 in response to pheromone. Finally, regulates filamentation via the repression of genes such as GAT2, HAP4, MGA1, MSN4, NCE102, PRR2, RHO3, and RHO5, when nutrients are plentifu.
Miscellaneous:
MISCELLANEOUS: Present with 1100 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSTSITVRNRDRSLPPLLLPNVSLLEKDIRRKGTQNVGITDPELLSTTWTRKRAFPTDELLGGYKRLKPAAADSNECAIGIATVTPPPTLPVSAIVPPPQNYTPPLFEYHPHALASMVNEDANASCTQMSIISRSTSNSTTSSATSTSSISKRQRSGPSCDKCRLKKIKCNAKIEILLQDDTIMPMISNKLRYVLTPDDIRLYRGTLLRNIAIPDDVIEGTGSRKLIKHIDKLVLLTPCLPCIKKKHSSSSTNFPKNDKCTFSKGFTRADINISSKISLKFKDKTIYDITYDDYKSIDF
The following text describes a protein:
Function:
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
Sequence:
MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGSYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHRKRKLLENSSLNSKLLKVNGSTAAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDSNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSANNKCCINGASTVVTTIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHLKRFHWTAYLRNKVDTYVQFPLRGLDMKCYLLEPENSGPDSCLYDLAAVVVHHGSGVGSGHYTAYAVHEGRWFHFNDSTVTVTDEETVGKAKAYILFYVERQARAGADKL
The following text describes a protein:
Function:
Involved in the production of the isoprenoid antibiotic terpentecin. Converts terpentedienol diphosphate (TDP) into terpentetriene (TTE). Can also accept geranylgeranyl diphosphate (GGDP) and farnesyl diphosphate (FDP) as substrates.
Sequence:
MPDAIEFEHEGRRNPNSAEAESAYSSIIAALDLQESDYAVISGHSRIVGAAALVYPDADAETLLAASLWTACLIVNDDRWDYVQEDGGRLAPGEWFDGVTEVVDTWRTAGPRLPDPFFELVRTTMSRLDAALGAEAADEIGHEIKRAITAMKWEGVWNEYTKKTSLATYLSFRRGYCTMDVQVVLDKWINGGRSFAALRDDPVRRAIDDVVVRFGCLSNDYYSWGREKKAVDKSNAVRILMDHAGYDESTALAHVRDDCVQAITDLDCIEESIKRSGHLGSHAQELLDYLACHRPLIYAAATWPTETNRYR
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside. AMP is the major substrate but can also hydrolyze dCMP and IMP.
Subcellular Localization:
Cytoplasm.
Sequence:
MEPGQPREPQEPREPGPGAETAAAPVWEEAKIFYDNLAPKKKPKSPKPQNAVTIAVSSRALFRMDEEQQIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNRRLRELYPDSEDVFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTPRRTAPAKQAPSAQ