lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination of target proteins, including p53/TP53, TP73, HDAC1 and CDKN1B. Mediates ubiquitination and degradation of p53/TP53; preferentially acts on tetrameric p53/TP53. Catalyzes monoubiquitinates the translesion DNA polymerase POLH. Involved in the ribosome-associated quality control (RQC) pathway, which mediates the extraction of incompletely synthesized nascent chains from stalled ribosomes: RCHY1 acts downstream of NEMF and recognizes CAT tails associated with stalled nascent chains, leading to their ubiquitination and degradation.
Subcellular Localization:
Cytoplasm. Nucleus speckle.
Sequence:
MAATAQEDGVRSPAPGPRGCEHYDRACLLKAPCCDKLYTCRLCHDTHEDHQLDRFKVKEVQCINCEKLQHAQQTCEDCSTLFGEYYCSICHLFDKDKKQYHCESCGICRIGPKEDFFHCLKCNLCLAMTLRGKHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDIEVAQTPMPSEYQNVTVDILCNDCNGRSTVQFHILGMKCKLCDSYNTAQAGGRTVSMDEQ
The following text describes a protein:
Function:
Involved in peptide utilization.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MQKSLVSLAWVFVAILGAICLGVLALHKGESINTLWLVVASACIYSIGYRFYSHFIAYKVLKLDDSRATPACVRNDGKDFVPTDKAITFGHHFAAIAGAGPLVGPILAAQMGYLPSILWILIGSVLGGCVHDFVVLFASIRRDGKSLGEMIKLEMGQFVGMIASLGILGIMLIIIAILAMVVVKALAHSPWGFFTIAMTIPIAILMGLYMRFFRPHKILEVSVIGFILLIIAIYAGKYVSLDPKLASIFTFEASSLAWMIMGYGFVASILPVWFLLAPRDYLSTFLKIGVIGVLVVAIIFVAPPLQIPKITPFVDGSGPVFAGSVFPFLFITVACGTISGFHALISSGTTPKMLAKESDARLVGYGSMVMESVVALMALVCAGILHPGLYFAINSPEVSIGKDIADAASVISSWGFNISAEEIREMTKNIGESSILSRTGGAPTFAIGLAMIVYHILGDPSVMAFWYHFAILFEALFILTAVDAGTRTARFMIQDLLGNVYKPLGDLSSYKAGIFATLLCVAGWGYFLYQGTIDPKGGIYTLWPLFGVSNQMLAGMALLLVTVVLFKMGRFKGAMISALPAVLILSITFYSGILKVVPKSDNSVLNNVSHVAQMQIIKEKMATTTDEKALKTLQKSFFNHAIDAILCVFFMLVALLVLIVSVRICSNAYFKNKIYPPLAETPYIKAS
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Sequence:
MKLAKKYYAVRKGRVPGIYKTWKEAEEQVKGFPGAEYKSFERLEDAKAYMEGKNECICPELDTETMIAYVDGSYDEVCGSGIVLCYRGKKEEYYFWTNIEEFKDSRNITGEIMAALFAMDYALKKGARKLVLRYDLEGLEKWATEEYRTNKLVTKVYRHYYRKFCQMGLKVVFEKIKSHSGNFCNDEADSLAKKASKKESNVEWMPEDFESIIRTLTKKGGCL
The following text describes a protein:
Function:
Thrombin inhibitor. Prevents blood clotting to allow insect to feed on blood. Also functions as an inhibitor of trypsin and plasmin.
Subcellular Localization:
Secreted.
Sequence:
LIKELVNMVIQHAEEEEVKELKNPCECPRALHRVCGSDGNTYSNPCMLNCAKHEGNPDLVQVHKGPCDEHDHDFEDPCKCDNKFEPVCGDDQITYLNLCHLECATFTTSPGVEVAYEGECHAETTNAMEVLFQGNPCECPRALHRVCGSDGNTYSNPCMLTCAKHEGNPDLVQVHEGPCDEHDHDFEDTCQCDDTFQPVCGDDEITYRNLCHLECATFTTSPGVEVKHEGECHPETKVNQLILKSCMCPKIYKPVCGTDGRTYPNICVLKCHISSNPGLGLAHLGECKVAVLAKETGEVRNPCNCFRNFNPVCGTDGKTYGNLCMLGCAAETKVPGLKLLHNGRCLPKEQL
The following text describes a protein:
Function:
Mediates the viral entry into the host cell together with fusion/F protein. Attaches the virus to sialic acid-containing cell receptors and thereby initiates infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion; Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
Subcellular Localization:
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Domain:
The C-terminus (head domain) is involved in binding the cellular receptor.
Sequence:
MNRAVCQVALENDEREAKNTWRLVFRIAILLLTVMTLAISAAALAYSMEASTPGDLVSIPTAISRAEGKITSALGSNQDVVDRIYKQVALESPLALLNTESIIMNAITSLSYQINGAANNSGCGAPVHDPDYIGGIGKELIVDDTSDVTSFYPSAFQEHLNFIPAPTTGSGCTRIPSFDMSATHCYTHNVIFSGCRDHSHSHQYLALGVLRTSATGRVFFSTLRSINLDDTQNRKSCSVSATPLGCDMLCSKVTETEEEDYNSVIPTSMVHGRLGFDGQYHEKDLDVTTLFGDWVANYPGVGGGSFIDNRVWFPVYGGLKPSSPSDTGQEGRYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRVQQAILSIKVSTSLGEDPVLTIPPNTVTLMGAEGRVLTVGTSHFLYQRGSSYFSPALLYPMTVNNNTATLHSPYTFNAFTRPGSVPCQASARCPNSCVTGVYTDPYPLVFHRNHTLRGVFGTMLDDEQARLNLVSAVFDNISRSRITRVSSSRTKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKDDGV
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MLNGDYVFGWQDYIRSQRANSAAMNHFHIYEAIGRGKYSAVYKGRKKKTIEYFAIKSVEKCHKSKVLQEVRILHSLDHLNILKFYSWYETSAHLWLVLEYCVGGDLMTLLRQDSQLPEDSIHDIARDLVRALQFLHSKGIIYCDLKPSNILLDENGRVKLCDFGLARKLSEMSKTPSSMLPQAKRGTPCYMAPELFDDGGVHSYASDFWALGCVLYECYAGRPPFVGREFTQLVKSILSDPTPPLPGNPSRPFANLINSLLVKDPAERIQWTELCGHAFWNTKFALVPLPSQPAFDNMIELYAKPCLSECNGDRSSQNKTPPKHCEKDVKGTPKPNENSILGSSGHETPVKDILSGRKIQTKTFRGVEEKQRVPSSASRGVNLLRLSRIAKSNLQRENEKENYRRPMPNSYENDAEVKIENTDMELNFNENAEDDTHDEPDGSDNSSSIPEEVESNIHQLETSPVVNMPASDESRTNDQESSSEYVDIATTPLTASPQVKTQRAKEGVEATEFDSLKSSNKLSEVLWHPSDLSVRPVMPSRKADKASEVIPSLPFEALKPSDFVKMSKEQLDALNNRIISTFNGNNNTGEKQNLIRYLEILSSNADAANILTNGPIMLMVVKMLRLSKASALRVQLASLIGLLIRHSTFIGDDLASSGILGSLTAGLRDRQEKVRRFSMAALGELLFYISTQNEQSRDNNTLESPSKDSRSTFGWQVPNSLISLVSSVLRKGEDDITQLYALRTIENICSQGGNWAARFTSSDVISNLCYIYRATGKQESIRLTAGSCLVRLARFNPPIIQSIIEKLSFKDTASALVKGSPREQQVCLNLLNMAMLGSHMFTNIGRHLLPLAEDKNLVPSLLSLTEQGSEILRGKTLLFTALLCKNGRRWLPHFFCNPRLLSAVDRLAKEKDSYLQQCLDAFVRIVVSSVPSLLDIITTDIQQMMGGRRNGHFSAISSRVTPKTNIHSLPVVLHLLGSSSLKCRVVNNQVLQQLTNLVKVLETPFQGRDDLQITLLRILESIAEESSLILESPDILIGEILPSLAILYKGNKDGDARFLCLKILFDVMVIFLNEPFDDEQRSQALKAISNIHFLPLYPALIEDEDPIPMYAQKLLVMLIEFDCIKISDILHLKTVSQCFEFLLGDLSNANVNNVKLCLALASAPEMDSKLLSQLKVVRKVGNLLEFVYAKDMEDFLEPTLALCRAFLLCSVGRKRGLAYRQEPALLNDVSSEASGPIDPQQCIRDTMEFGGNVGVLLELSGSSEVNIADIASECVVLLLKAAPREATTGFLTNLPKVSAILESWRKGVPHLILRRMLHALGYSCRQYLSHAMILSISKTEVSRLEAIILELKNSSTYDLANAALRVASELHRLPRCI
The following text describes a protein:
Function:
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MHATVTATQHILQSVTTHRYELVAVLISGIVAYFATVRFVQGARIKLIQRRLCGIDINKTTPEQRKKIASKPYDELDEGEKRLVVPESFGILAGAVYLSAVLITTSVAFGGVSRQLDGSVTSIAVMLLLGFVDDVLDLRWRYKILLSAIGTIPLVMTFKGSLEVIVPRLLAPYLGSPTLYLGVFYLVGLSLLCIFCTNSINILAGVNGVEVGQSIVIAVASIVHCIMQMRLESDPSYGGPATSGQLLAIALLVPFVGVSAALWRFNSYPASIFVGDSYTYFAGTVLSVAGVTGVYSKTLMLFFVPQLVNFAISLPQLLRIVPCPRHRVPRWDMKRDVMQNSGNYTLLNAILLLRGDMHERDLTRAALKLQIVSCIVAMFARYFLASLLYDHVY
The following text describes a protein:
Function:
Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity. Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1. Probably only regulates a subset of ATR targets.
Subcellular Localization:
Nucleus. Note=Localizes at sites of DNA damage following replication stress. Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex.
Domain:
The RBM1 (RPA1-binding, also named RPA70N-binding) motif mediates interaction with RPA1. The RBM2 (RPA2-binding, also named RPA32C-binding) motif mediates interaction with RPA2; The ATR-activation domain (AAD) motif is required to bind and activate ATR.
Sequence:
MSRRRKHDDSPSPKKTPHKTVAAEECGSVVEPGRRRLRSARGSWPCGAREGPPGPVRQREQPPTAALCSKSNPEERYETPKRALKMDSLSSSFSSPNDPDGQNDIFWDQNSPLTKQLGKGRKKQIYTTDSDEISHIVNRIAPQDEKPTTNSMLDMWIGETAIPCTPSVAKGKSRAKISCTKLKTQSQEEELMKLAKQFDKNMEELDVIQEQNKRNYDFTQMISETEILSNYKDNIQMWSLHNIVPEIDNATKKPIKGNTKISVANNQNSSQKPFDQIAEAAFNAIFDGSTQKCSGQLSQELPEAFWSTSNTTFVKTNALKEEKIITNETLVIEKLSNKTPRSLSSQVDTPIMTKSCVTSCTKEPETSNKYIDAFTTSDFEDDWENLLGSEPFAMQNIDMPELFPSKTAHVTDQKEICTFNSKTVKNTSRANTSPDARLGDSKVLQDLSSKTYDRELIDAEYRFSPNSNKSNKLSTGNKMKFENSSNKIVIQDEIQNCIVTSNLTKIKEDILTNSTEASERKSALNTRYSNEQKNKCILNQSIKAPVNTDLFGSANLGSKTSVSNPNQTSASKVGSFFDDWNDPSFANEIIKACHQLDNTWEADDVDDDLLYQACDDIERLTQQQDIRKDSKTSESICEINNNSEHGAKLTQQQDIRKDSKTSESICEINNNSEHGAKNMFAISKQGSNLVQSKHLNPGSISVQTSLTNSSQIDKPMKMEKGEMYGNSPRFLGATNLTMYSKISNCQINNLHVSYTNTDVPIQVNSSKLVLPGSSSLNVTSDHMNTEITTYKKKLSTNQPCHKTVTDEAQSNLNTTVGFSKFTFTRMKNSQILSQFNQNCITGSMSDTKITQGVEKKKGVNPLLEEAVGQQSLVKLSESLKQSSKEEEEKNRKCSPEEIQRKRQEALVRRMAKARASSVNAAPTSFL
The following text describes a protein:
Function:
Probably catalyzes the addition of a phosphoethanolamine moiety to the dephosphorylated 1-position of the disaccharide backbone of lipid A. Lipid A that is 1-phosphorylated is not a substrate for this enzyme.
Miscellaneous:
MISCELLANEOUS: In this organism most lipid A is tetraacylated without a phosphate group at the 4'-position and has a phosphoethanolamine residue at the 1-position.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MASLFHLRFLKPLSCLQAGLLYSLIFGVLYHFPLFVYVYKESNQVSFIAMMVVVLFCVNGALFLALGLISASLMRWSAIVFSLLNSVAFYFISAYKVFLNKSMMGNVLNTNTHEVLGFLSVKLFVFIVVFGVLPGYVIYKIPLKNSSKKAPFLAILALVFIFIASALANTKNWLWFDKHAKFIGGLILPFAYSVNAFRVSALKFFAPTIKPLPLFSPNHSHSFVVLVIGESARKHNYALYGYQKPTTPRLSKRLADNELTLFNATSCATYTTASLECILDSSFKNNAYENLPTYLTKAGIKVFWYSANDGEKNVKVTSYLKNYELIQKCPNCEAIAPYDESLLYNLPDLLKEHSNENVLLILHLAGSHGPNYDNKVPLNFRVFKPYCSSADLSSCSKESLINAYDNTIFYNDYLLDKIISMLENAKQPALMIYLSDHGESLGEEAFYLHGIPKSIAPKEQYEIPFIVYANEPFKEKHSIIQTQTPINQNVIFHSVLGVFLDFKNPSVVYRPSLDLLKHKKE
The following text describes a protein:
Function:
In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
Subcellular Localization:
Nucleus.
Sequence:
MVNVLKGVLIDCDPAVKQFLLHLDEHNVLGKKFVIEDLDETHLFVSAGIVPILQEKVWELMDTNSFNISQS
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MAQTTEGASESVKVVTFSFMTNEEVRKQSVVKVTAPILLDGMGRPVSGGLYDPAMGSLDETTLCKSCGQRPFYCPGHCGHIDLVSPVYNPLLFVILHNFLRCTCFSCHHFRAGESMVENCKTLLELILDGEIAKAKELEEEWMNSKSRTKSSHSMYTYERKNGQPETWTSLQFSEAISVVTKFLKPKQSNCKYCGAKSPKITKPTFGWFHMKGLAGVQKRANAIRRSKPVSVSSGAEGVSSLEEETTTEATVEDFEDVSPEVFMQKNFSSGHLLPSEVKDILKRLWKNEALLCSFISDISQQGHGNKAGHSMFFLESVLVPPIKFRPPAKGGDSVMEHPQTVLLNKVLQSNISLGNGHANKSEHSKIVRLWMDLQQSINILFDSKSAAGPGKNDASLGICQLLEKKEGMFRQKMMGKRVNFACRSVISPDPYLAVNEIGIPPYFALRLTYPERVTAWNVQKLRNAIINGPETHPGATHYIDKLATVKLNLKPSRKSRISISRKLPSSRGVVVDQGCDDYEFEGKIVNRHLQDGDIVLVNRQPTLHKPSIMAHVVRVLKGEKTIRMHYANCSTYNADFDGDEMNVHFPQDEISRAEAYNIVNANNQYVKPTSGEPIRALIQDHIISAVLLTKKDTFLNFDEFSQLLYSSGISTSKACASSEKPGQKIFTLDFDAEMLPVLPAVWKPEPLWTGKQVVTALLDHITQGSPPFFVEKDVKIPRGFFKCRDMGNNSSKVKMVDGDKSKRKRTMNENKLEKGEVLDEGNSKKKEHTKVDKLKAARLDDDSLLIFKNELVRGVIDKAQFGDYGLVHTVQELYGSNTAGLLLSVMSRLFTVFLQTHGFTCGVDDLLLIECMDKEREKQLQICEKIGEQVHLGFLKVKDGEKLDPMTLQLNIEKTISYNGEAALTSLDRKMTSQLNERTGNSKVLKDLLSEGLLKPSVKNCISLMTTSGAKGGTANFQQISSHLGQQQLEGKRVPRMVSGKTLPCFPPWDWASRAGGFIVDRFLTGLRPQEYYFHCMAGREGLVDTAVKTSRSGYLQRCLIKNLESLKICYDHTVRDADGSVIQFQYGEDGVDVHKTAFITKFEALAANQDMLYENSHHQLGKYNVFINELPSALREKGEFIYNSLSKDKVPGLVLKEDFIRLLENKYLSSLAQPGEPVGVLAAQSIGEPSTQMTLNTFHHAGRGEMNVTLGIPRLQEILMTASQDIKTPIMTCPLKEGYSMDVAKGLANKLKKITVADIIESMNVTVVPFSQRKREICSIYKLRIDFYPLENNAQHGHISPEDLENTLETVFLEELEGLIEREMVLLSKINGIKNFVPDSQSKGSSEGDEVSSSRQEENDDDDDEGNDLDVAEDLGSDMKKQKLQANDEMDYEDDSEDDLNAKESSTGFESEVDQGDEAEITNNDMIEIVKDSASENQPEIVDVSKSMSKEKTTETSKEKKKVKSELVRKETDRSIFVEAKENHFEVHFKFTNEPHTLLSQIVQRAAQKVSIQRSGKIIQCQQITCKEGQVIYHGNNLKERKNLKPEEKEKIPALQTSGVDFKTLWEMQDELDVRYIYSNDIHAMLQTYGVEAARATIIREIQNIFTSYGISVNIRHLSLVADYMTHSGGYRPMSRLGGISDSISPFSRMTFETAGKFIVQAALHGEVDNLETPSSRICLGLPVKMGTGSFDLMQKIEV
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MMDGSTAAAAELEAAERVVMRWDSTASASYGGGGGDEQMLFDGGGDRVEAERFLRAVDDLRRLAPPSPATVGSPRRTSSASGGGGAASNAVQVAMARLEDEFRHVLSSRALDLEIEALADLTSLSMCSDRTNSADVAEEAAAADEDDSVSSSVGRRSSYRSLRSIREIDLLPADAISDLHAIASRMAVAGYGRECVQVYASVRKPAVDSALRRLGVEKLSIGDVQRLEWEVLEAKIRRWIRAARAAVRGVFASERRLCFLIFHDLPLSSSTITTATHDAPFAEAVKGAALQLFGFAEAISIGRRSPEKLFKIIDLHDAIADLLPDVSDIFAASKAGESIYVQAAEIRSRLADAVRGILSEFENAVLRDPSKTPVPGGTIHPLTRYVMNYSSLISDYKTTLSELIVSRPLACSRIAPEGNENAPSFPDLDLADPDSQLPLAAHLIWIIVVLEHNLESKASLYKDAALSHLFVMNNVHYIAHKIKDSPELRGLIGDEYLKQLTGKFRLAATRYQRTAWLKILNCLRDEGLHVSGGFSSGVSKSALRERFKSFNAAFEEAHRVQSAWYVPDTQLREELRISIAEKLLPAYRSFLGRFRHHIENGRHPELYIKYSVEDLETSVTNFFEGCPPSLHNRRRSHG
The following text describes a protein:
Function:
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
Subcellular Localization:
Chromosome, telomere. Nucleus.
Sequence:
MSDKPCEPSWEQIVNRWSFDFYAFQAFSAFRNGDYTAFTHFINIIESVVVRPVDGHPDMIPQLRLMQFLSRINNGDKLDLTFEEPKTPLESALDVLESICRDMSVPHPEQQLIRHAISEMLVMVCIRSGEFEKAEEMLKHFSSSSDSAGKKKLLLNLIRCRRSSHSVLQLSSYSHFKQDMLQFVERLFSVPEPFLLQMLRRSGWPSQRPEVRRSTQNNRRFTGKPSKRTPPHSSAAEDHGAECVSAVSRQGLQQVFDLLSEQYGVGISFFQLQDSVEVEAQQQQEGGVAGPELCLTLSETPMQTVILSDTEEQDEPRRYAGMTISRLVQEEDSQISAEHTHIEDDEEEEQTHTHRGGDCSLSEPQCSSTQRSTPARLCKRSNTRVQQRSIRVSSGSEPEVDSTSPAAHTRRSTPTSTHTRTTKRSKWLDASGIQDNWSDEDSLFHTSTAPAKKYTRKMWSVQESEWLKQGVVRYGVGHWERIRSSFPFAGRTAVNLKDRWRTMVKLKMV
The following text describes a protein:
Function:
Acts as a component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and KAR2 in a channel-forming translocon complex. In an initial step, the signal sequence seems to bind simultaneously to SEC61 and SEC62. SEC62 and SEC63 are required for interactions between SEC61 and translocating polypeptides. SEC62 may affect SEC1-polypeptide interactions by increasing the affinity of targeting pathways for SEC61 and/or by modifying SEC61 to allow more efficient polypeptide interaction. A cycle of assembly and disassembly of Sec62/63 complex from SEC61 may govern the activity of the translocon. SEC62 is essential for cell growth.
Miscellaneous:
MISCELLANEOUS: Present with 16500 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSAVGPGSNAGASVNGGSATAIATLLRNHKELKQRQGLFQAKQTDFFRYKRFVRALHSEEYANKSARQPEIYPTIPSNKIEDQLKSREIFIQLIKAQMVIPVKKLHSQECKEHGLKPSKDFPHLIVSNKAQLEADEYFVWNYNPRTYMDYLIVIGVVSIILALVCYPLWPRSMRRGSYYVSLGAFGILAGFFAVAILRLILYVLSLIVYKDVGGFWIFPNLFEDCGVLESFKPLYGFGEKDTYSYKKKLKRMKKKQAKRESNKKKAINEKAEQN
The following text describes a protein:
Function:
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
Sequence:
MASPNLSPGGVYRCKVLVSSSKSAVGTVLSDTIVQQCRSALQSRDVFTIALSGGSLPSFLQSLPAAFETAGVDPQWQKWHVLLADERCVASTDADSNLKAIRENFTDGAPIPGCQVYGIDESLLSSTEAMATAYEGTVVKPLLDKSGGILDSVVLGFGPDGHTCSLFPNHPLLNEQIRLVASIDDSPKPPPSRITLTFPVLNKFSRQVIFCGAGSSKSPILQSVFGVFRPLPDDPIGKVDAGSKAYLVEMNDPPPYPCAMVRPETGTLVWVVDAEAAKEQMAV
The following text describes a protein:
Function:
Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MNIFRLIGDILHLVSMYILIMKLKKSKNCIGISCRMQELYLIVFLCRYIDLFFVFVSFYNTVMKITFILTIAYTIYLIRLKLPISQTYNRKVDNFKSEKYLIPPCLVLSLLTCKTYNLYNILWSFSIWLESVAILPQLVLLEKQREVENITSHYVITMGLYRAFYILNWIYRYFFDDKPYINVVGWIGGLIQTLLYIDFFYYFALAKWYGKKLVLPFNGEV
The following text describes a protein:
Function:
Acts as a linker essential in the assembly of a core complex of PRK/GAPDH. Coordinates the reversible inactivation of chloroplast enzymes GAPDH and PRK during darkness in photosynthetic tissues.
Miscellaneous:
MISCELLANEOUS: Binds copper and nickel ions. Copper ions catalyze the oxidation of reduced thiol groups and thus promote formation of the disulfide bonds required for linker activity (By similarity).
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MTTIAAAGLNVATPRVVVRPVARVLGPVRLNYPWKFGSMKRMVVVKATSEGEISEKVEKSIQEAKETCADDPVSGECVAAWDEVEELSAAASHARDKKKAGGSDPLEEYCNDNPETDECRTYDN
The following text describes a protein:
Function:
Implicated in yeast microtubule function.
Miscellaneous:
MISCELLANEOUS: Present with 468 molecules/cell in log phase SD medium.
Sequence:
MGLLSIIRKQKLRDKEIRCLILGLDNSGKSTIVNKLLPKDEQNNDGIMPTVGFQIHSLMIKDVTISLWDIGGQRTLRPFWDNYFDKTQAMIWCIDVSLSMRFDETLQELKELINRDENRIGYECAVIVVLNKIDLVEDKSELHRRCLLVESELKCLFKPDIRIELVKCSGVTGEGIDNLRDRLVESCHFTQ
The following text describes a protein:
Function:
Required for spermatogenesis. Essential for de novo DNA methylation and silencing of transposable elements in the male embryonic germ cells. Not required for piRNA biosynthesis.
Subcellular Localization:
Nucleus.
Sequence:
MDKYALLQRAKLHLDFIHANSTTHSFLFGALAELLDNARDAGAVRLDVFSVDNETLQGGFMLCFLDDGCGMSPDEASDVIYFGTSKKRLSTLKFIGQYGNGLKSGSMRIGKDCILFTKKEETMTCLFFSQTFCEKEGLTEVVVPIPSWLTRTRESITDDPQKFFTELSIIFKYSPFKTEAELMQQFDMIYGRCGTLLIIYNLKLLLSGEPELDVTTDKEDILMAEAPEEIPERRSFRAYTAVLYFEPRMKIFIQAKRVQTKHLCYSLYKPRKYQYTTSSFKGKFKTEVQKAEEAVKRAELLFKEVQAKVNQPDRIALSSTQDALQKALQDVDTKHKSLRQKQRALRKARTLSLFFGVNTEDQHQAGMFIYSNNRLIKMYEKVGPQLKMKSLLGAGIIGIVNIPLETMEPSHNKQEFLNVQEYNHLLKVMGQYLIQYCKDIGISNRNLTLFWDEFKYQHSKDTDSSLESLQWRRRQAMGIPFILQCDLCLKWRVLPSSSNYQEKGLPDLWICASNPNNLENSCNQIERLPSIPLGTVNRRPPSKDERERQLQESVQRYQDKLVEAQPQKSQLIVTSKIPEFKSSCLSSALKEKSKLGRIQPSGADLTQGSPSSVKLSFMQRSQKRSTEDTHSDVEFICMTKIPKKSVKKTVKYLQPGHAPALLENLKLEDTAQVSSREIKKQQSESLVQAGKASTDVASSRDPTVTMVWDQSSTKVSLKQEEEEEVPLIKPDKQELCDDTPVVKGNSSALHWKSLPGVQMEDLSPRSGHKINSVSGDCQLPASPMPSQSMSVEETARKLLSNLREILLYFVPEFQLSSEFECTSVEELITNPELERCPENINEKLKTCFNQIQNIYMAQYEKRLKRKMQSIVYEANRRGLLNQVFLGQCELKRKRTEEKLSDLRAKLALLLQKLQLGGPAGDPQQIDAYLEDLLKEDRLPTALHEKSPESA
The following text describes a protein:
Function:
Involved in plant defense. Contributes to resistance against parasitic plant C.reflexa. Acts as a receptor for the 11 kDa glycine-rich protein (GRP) of C.reflexa inducing immune responses such as emission of stress-related phytohormone ethylene, reactive oxygen species (ROS) release, and hypersensitive cell death. Recognizes a specific pathogen-associated molecular pattern (PAMP), a cysteine-rich peptide 21 (crip21), from GRP located on the cell wall of C.reflexa.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Cell surface.
Sequence:
MGNIKFLLLVFFLIVVVVNGCWEEERNALLELQTNIMSSNGELLVDWAGYNAAHFVDCCFWDRVKCSLETGRVIKLDLEADFGTGDGWLFNASLFLPFKSLQVLLLSSQNIIGWTKNEGFSKLRQLPNLKEVDLQYNPIDPKVLLSSLCWISSLEVLKLGVDVDTSFSIPMTYNTNMMSKKCGGLSNLRELWFEGYEINDINILSALGELRNLEKLILDDNNFNSTIFSSLKIFPSLKHLNLAANEINGNVEMNDIIDLSNLEYLDLSDNNIHSFATTKGNKKMTSLRSLLLGSSYSNSSRVIRSLKSFSSLKSLSYKNSNLTSPSIIYALRNLSTVEYLYFKGSSLNDNFLPNIGQMTSLKVLNMPSGGNNGTLPNQGWCELKYIEELDFLNNNFVGTLPLCLGNLTSLRWLSLAGNNLHGNIASHSIWRRLTSLEYLDIADNQFDVPLSFSQFSDHKKLIYLNVGYNTIITDTEYQNWIPNFQLEFFAIQRCIALQKLPSFLHYQYDLRILAIEGNQLQGKFPTWLLENNTRLAAIYGRDNAFSGPLKLPSSVHLHLEAVDVSNNKLNGHIPQNMSLAFPKLLSLNMSHNHLEGPIPSKISGIYLTILDLSVNFLSGEVPGDLAVVDSPQLFYLRLSNNKLKGKIFSEEFRPHVLSFLYLNDNNFEGALPSNVFLSSLITLDASRNNFSGEIPGCTRDNRRLLQLDLSKNHLQGLIPVEICNLKIINVLAISENKISGSIPSCVSSLPLKHIHLQKNQLGGELGHVIFNFSSLITLDLRYNNFAGNIPYTIGSLSNLNYLLLSNNKLEGDIPTQICMLNNLSIVDLSFNKLYGPLPPCLGYLTQTKKDAEISWTYFAENYRGSWLNFVIWMRSKRHYHDSHGLLSDLFLMDVETQVQFSTKKNSYTYKGNILKYMSGIDLSSNRLTGEIPVELGNMSNIHALNLSHNHLNGRIPNTFSNLQEIESLDLSCNRLNGSIPVGLLELNSLAVFSVAYNNLSGAVPDFKAQFGTFNKSSYEGNPFLCGYPLDNKCGMSPKLSNTSNINGDEESSELEDIQCFYIGFVVSFGAILLGLAAALCLNRHWRRAWFRMIEALMFYCYYFVLDNIVTPIKSRWYKNVG
The following text describes a protein:
Function:
Plays an essential role in chain termination during de novo fatty acid synthesis.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MASTHEPFPGGCVKPRLDVQACWRWIWSNACNDPAPWVVSGVHVQCFMGRCAEIDTWVAGKNGMRLMRDYKSGQILARATSTRVVMNQTTRRLSKMPNDVREEITPFYLPSPRHGDLDMNHEQRKIHRMDAGDHDISSLTMEYRRECGQNDVVESMTWVQHADCLIADDDLETKRVNFGGSDEETLPSFEF
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MAGHVSPKVIFRDVAVYFSEKEWDLLEGWQRDLYTGVIKEIHGILISLGFIILNPNNFLRIQPEDEPCLKSRNVLERNESINITEPDCGLVNPDILLTVQLGEKQHVADTYEENGGRNVSLPSTSKFIDKFGEYTAVKQEAHLADYTSIPNVKPLNSPKKRYPCNEPVLRRVSIQEQPSNSLHLELKRGIRYSTVQGNRASTSGLSKPNAVAVPGKFIIKKPYNMCDKNFNVKAYPKIEPLTLKVKSKELPSNTENVSLEGRKMVNYINVDETISERQVTQKLNLGNIPLKNKGKVQYNLKSSGYCQRMLRWSITQKEEVTQKRYLAGAQVSKEPERSFNCTECGKRFLKLSDLRLHQGSHRIKIKQLNGCVIQLKSHQNVQASQRLSIEQKNSNTGSPKNISGAKSLTCAVYGKNVSPNTHVVPHQKTLVRERRFVCKFCGKRFQNNSNLIGHERIHTGEKPFECPECGKSFSQKANLTTHQRLHTGERPFVCITCGKGFAQKINLLTHEQTHAKKKKKVDGKHIMIN
The following text describes a protein:
Function:
Lipid transfer protein required for autophagosome completion and peroxisome degradation. Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion. Atg2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region. The latter binding is assisted by an atg18-PtdIns3P interaction. Atg2 then extracts phospholipids from the membrane source using its NR and transfers them to atg9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
Subcellular Localization:
Preautophagosomal structure membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Sequence:
MTYFLPSFFQKRLLKYALSRLEFIDTEALDPDSLGIRWGQRSTVELRDIGLRLEKLATLLHLPASSKLLAARIRLLRLTVPADIYSSGIICEASGIDVHLHFPSEKEASAARTSLFESHEFGHESIIPNPADLAESFLQAEPKEEKEELQAALSSRSEILHRTSSSISDDEEELGLGDETVSLPSFVAAFLKGVADRLQVHVDEVSIRLDVEMKQDGPSKRQPEEKPDLISGLLIIRQISVGAVVTASSSDELHPGKRPISLSAIELALVSEPIVFSNYSQFTAPTSPSSPLRSKSSQSSSPASSVPPAPSSASSSTHAMMASTIFEPSQPTVDIPEDEHGVAKLEGSIYTYDGRFSDADTDENRSHGYLEESQDLSEKLLDDPAYLDSVIDSHLQDDDSEGLGDIQPGDIKPGDSNQSYTDRSTPSQPSLGFQAPALVDPHSRSGDHSVAVASMPNIRNIERPLDQYGPQSSMPVLSRPLTQDITGNNSQESQPAPPSPSETSSSGSVSAYFNNDLSESRLFSPEEAQSMYMSAMSHRSDSRSFIPDIPGAWDSPEATLRREAIQHHGSLGHTDETTEALEDQDRTPVSTPKPTDRETKYHSGHTLGQQQESYSESTDKHSIQPSPDVNETTKVSKSFLHIDKVTIWIPSTKPTKDHQDISEPLDARSAGGSFKDSTTHLEASQVRERSVSFSKPPSSLRTRRDSTELALAGTDTKSYTKYGLGSLNSTNISVEISCIEVQFDISIGWLMIKIGQRVLQGFGDIGQPKTSKKSTERDVQSPQDIDFTLGTLCIKFVELVPGKSFPLEEQQDPSTTFFDLLHDSVLLQSTVSGVQAHYSNANNVTDFSAAVSKFTIKFATEDLISFSEDMKMRESTKDGLLPTGNDIVLSLSKSQDSATFKTDTLPLCVSLNIQRLEDLLGRFGGLSTIMELGSSISSMSGSKGPKNDVPRRTRGVRFAGSPQSPVRSPTPSVPWKVNARIGGIVLDVSGENHYLTLRTTAAKIISRYEMMAVQIDKAKLSGPLSIHSGKDAPAKVSLNNIRVEFLYTPKEPDLDRLLSLITPSKDKYDDDDDIMIDTLFRQRKQGSVLRVTVSGAKVVVSRPELGPLQQLGEELGRLSSVAKYLPEDDRPGILTLVLIRDVEARVHIGGQIGTIAANLENAEAAHISIPSLVAGQLGSIRVTRNGDEELIGEALPPKPGFAPLPVLMVRFIADEMEPTIRVKLHNLRVEYTVSAAMAFLGVSDEMTPGDVAANMASSLANIAELHPPLQDLEEGSTTPVKPMKLKVSMRDCVLGLNPRGTAAKGLIVLANSTFNGAIHDISSSEIALDLRKAFVMIIDDVRNTDARGNLPRRRAASPQSDQIQAFTDMGYVSVSSISSATAVVRIMRLTENGAKSLDVEVRDDLLILETCADSTQTLISILSGLQPPSPPSQLKKYRTEVVPIRDMLDSLSGDAFAADNLPIGAADQAEIQDHIPERDIDYVTDFHSMTASEEELASGPSSQVRDSFHSQCHVSSSMSELDFREDHFMQQSSVGGTAHRWDSTHNTYDLSDDSKLQNSPLRVRVRDAHVIWNLFDGYDWQRTRDTISKAVKDVEKKATDRRTSGRATAAFEDDEEAIIGDCLFNSVYIGIPANRDPAELRNDINRNIDDLISETGSYATTSTVTTARRNMSPGFRGKKLRLSRSKDHKMTFELKGICADLVVFPPGSQETMSSLDVRVKELEIFDHIPTSTWRKFATYMNEAGEKELGTSMVHLEILTVRPVSYLAASELILKATVLPLRLHVDQDALDFMSRFFEFRDDSTAPSGPSQEPPYLQRSEINAIPVKLDFKPKRVDYAGLRSGRTTEFMNFFILDEADMVLKHVIVYGAKGFDKLGQALNDVWMPDIKNNQLPGVLAGLAPIRSLVNVGSGVKDLVAVPVREYRKDGRIVRSIQKGAFAFAKTTSNELVKLGAKLAIGTQTVLQGAEELLSPPTGQATTGEEDEIDEDEAPKKISLYADQPVGVVQGLRGGFRGLERDLLLTRDAIIAVPGEVQESGSAKAAAKAVLKRAPTVILRPAIGVSKAVGQTLLGAGNSMDPSNRRKIEDKYKRH