lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MSSDSEDELLQIALQEQAQRDLNYQKTQASKTSKPVVNLVQPPPPPHKGSAPKNPSVKPAQMQKSRRAADDDDDSEVELLSISSEDEDSSKGRAFGTKNRGAGGGGRGGRDDTGDRGWDGEEPTCWKHVDEAELARRVREMRETKAVPVAQSLERKGSTLGQKGLNSLQSFARGMECIDPLGLGIIDNKSLRLVTEASESSPAKPDRDYLDAATREKLMYFSEKFDSKLFLSRIHQETSAADLEAGALALKTDLKGRTQQRKQLVKENFDCFVSCKTTIDDIESKLRRIEEDPDGAGTTHLYNCIQGVSSQAKRAFEPLFERQVQAEKIRSVQGMLQRFRTLFNLPSAIRGNINKGEYDLAVREYMKAKSIVLPSHVGILKRVLEEVEKVMKEFKGMLYKSMEDPQIDLADLENTVRLLLELDPESDPVWHYLNIQNNRIRGLLEQCTLDHEARVEALRNEIREKALSDAKWKKIQQDSTESSDVADSNIVGDAHFSIDSLSVDLAAEDVDALRGRYIRRLTAVLIHHIPAFWKVAVSVFSGKFAKSSQVSADPNVKASSNKLDDKAGDTKYSTHSLDEVAGMICSTISAYEFKVHNTFHDLEESNILCPYMSNAVKEISKACQAFDGKESAPPSTVTSLCALQLEITKIYILRLCSWMRTTTEEILKDESWVPVSILERNKSPYTISFSPLAFRTMISSAMDQINSMIMSLRSEATKSENIFLHLQEIQESVRLALLNCFIDFAGQLEQIGGELTQSRSSQETSHLQNGYLHEPEGKDQGLPPSNIAGDPHQKLLIILSNIGYCKDELSYELYNKYKHIWLQSREKDEEEDSDIQDLIMSFTALEEKVLAQYTFAKANIIRIAAVNYLLKAGVQWGGAPPVKGVRDAAIELLHTFVAVHAEVFAGAKPLLDKTLGILIEGLVDTFLNLFHENDTKDLKLLDANGFCQLMLELEYFETILNPYFTADARESLKSLQGVLLEKASESGTESTEVPGHHRRPTRGSEEALVDDRQQGMSVSPDDLIALAQQSSSEFLQAELERTRINTACFVDSIPLDSVPEPAKIAYASPRGPVDSPSRNYRGRQSVGSPSFSRHRRR
The following text describes a protein:
Function:
Required for shoot apical meristem (SAM) formation during embryogenesis. Negatively regulates ASYMMETRIC LEAVES1 (AS1) and ASYMMETRIC LEAVES2 (AS2 or LBD6). Probably binds to the DNA sequence 5'-TGAC-3'. Binds to RNA (By similarity).
Subcellular Localization:
Nucleus. Cell junction, plasmodesma. Cytoplasm. Endosome. Cell membrane. Note=Association with TALE/BELL proteins is necessary for nuclear location. Dynamic localization via a plasmodesmata-mediated cell-to-cell transport. This shuttle is repressed by MBP2C binding in cytosolic punctae, at microtubules. Subcellular localization and trafficking is regulated by FTIP3 and FTIP4, which promote endosome localization.
Sequence:
MESGSNSTSCPMAFAGDNSDGPMCPMMMMMPPIMTSHQHHGHDHQHQQQEHDGYAYQSHHQQSSSLFLQSLAPPQGTKNKVASSSSPSSCAPAYSLMEIHHNEIVAGGINPCSSSSSSASVKAKIMAHPHYHRLLAAYVNCQKVGAPPEVVARLEEACSSAAAAAASMGPTGCLGEDPGLDQFMEAYCEMLVKYEQELSKPFKEAMVFLQRVECQFKSLSLSSPSSFSGYGETAIDRNNNGSSEEEVDMNNEFVDPQAEDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSEQQKLALAESTGLDQKQINNWFINQRKRHWKPSEDMQFVVMDATHPHHYFMDNVLGNPFPMDHISSTML
The following text describes a protein:
Function:
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
Sequence:
MEFEQEYTAEEALNIEKEFTRLKGKHYMDHAGTTLYAESQIRAVHDMLAQNLFCNPHSSPLTGKLLQQVRHRLLRFFNTSPSDYSLVFTSGATASLKLVAESFRFRPPDEPESSPDEGAFVYLRDNHTSVLGMRSVVGTERIDPLEPEELLRHLKVSARCSGGTKPSLLVFPAQNNFNAAKYPLDLVEEIQQNGLSGYDDERFYVCLDAASYVSTNFLDLGRYRPDFVCMSFYKIFGYPTGLGALLIRNGSEDVLDKKYYGGGTIKIMLSGQNLHLKHDDLVTRFEDGTQPFLSIISLLEGMNTIQRLIPAANGYRPMERISKHVFSLAKYCYRKLGTLQHANGKKAILFYSDTRYETRDRQGGIVTFNVLKDDGSHLGFSEFAKFAGQHQIYVRTGCFCNAGSCQKHLGLTDEDILMFYEMGKVCGDDTDMIEGRPTGTVRVSFGYMNKKEDVNRLVDMINDCFVSKAVSNVAMVSPIRNVIKNEGIALKAIYLYPIRSCGGYRITAAWPLTERGLKYDREFTIVDSNGNPLMRNKHAEMSTIHPKIDPSLNFLILTHPFMEDLILKIRKLPTEFNDGESIDLGDAAAAWISKALRMPKLRLLRTSATDRKPPHKLLMINWDAMKTLSDDEGVESDATMSWLVDHFRGSLIVEGKAEEDLQGWKEVKIGKKRFKVQANCSRCPMIHVDQSGEAIPADSLKAIANVFTKKIPLGVHLTAVDEGFPEGVLECGSILEPVRQSDSPKAHIIKDSVSTRYNFLVK
The following text describes a protein:
Function:
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. May have a role in the localization of the LEM domain proteins Ote, bocks and MAN1 to the nuclear membrane. In spermatocytes, plays a role in maintaining type-A lamin LamC nuclear localization; regulates meiotic cytokinesis by maintaining the structure of the spindle envelope, and by contributing to the formation of the contractile ring and central spindle. Required for nuclear migration and to link the microtubule organizing center (MTOC) to the nucleus. In addition, is required for nuclear envelope localization of klar.
Subcellular Localization:
Nucleus. Nucleus inner membrane. Nucleus envelope. Nucleus lamina. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm. Note=Nuclear periphery. At metaphase and anaphase, weakly expressed in the nuclear envelope and spindle poles. Expression in oocyte cytoplasm increases after stages 6 to 7 of egg development. In spermatocytes detected at the spindle envelope, spindle poles and astral membrane throughout meiosis I, whereas mostly depleted in meiosis II. Colocalizes with nuclear pore complex component Nup107 throughout meiosis I.
Sequence:
MSSKSRRAGTATPQPGNTSTPRPPSAGPQPPPPSTHSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSVADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKSQKWVSADNTRTILLNSEGEAVANLDRIKRIVSQHTSSSRLSRRRSVTAVDGNEQLYHQQGDPQQSNEKCAIM
The following text describes a protein:
Function:
Chanoclavine-I dehydrogenase; part of the gene cluster that mediates the biosynthesis of fumiclavanine C, a fungal ergot alkaloid. DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan. The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity). The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by EasD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde. EasA reduces chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline. EasG then catalyzes the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine. Hydrolysis of festuclavine by easM then leads to the formation of fumigaclavine B which is in turn acetylated by easN to fumigaclavine A. Finally, easL catalyzes the conversion of fumigaclavine A into fumigaclavine C by attaching a dimethylallyl moiety to C-2 of the indole nucleus.
Sequence:
MASVESRIIAITGGASGIGAATCRLLAERGAAVLCVCDISPKNFDDLKISIKKINPSTKVHCATVDVTSSVEVRQWIEGIISDFGDLHGAVNAAGIAQGAGMRNTPTIAEEVDEEWTRIMNTNLNGVFYCTREEVRAMKGLPATDRSIVNVGSIASVSHMPDVYAYGTSKGACAYFTTCVAADAFPLGIRINNVSPGVTNTPMLPQFAPMAKTFEEIEESYKKEGLSLIEAEDVARTIVWLLSEDSRPVFGANINVGACMP
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MPQLQYPECYLAPNRCLVSNCGVNKMSNEELVGQNHGMEGEACTGEDVTFNDVAIDFTHEEWGWLNSAQRDLYKDVMVQNYENLVSVAGLSVTKPYVITLLEDGKEPWMMEKKLSKGMIPDWESRWENKELSTKDIYDEDSPQTVIIEKVVKQSYEFSNSKKNLEYIEKLEGKHGSQVDHFRPAILTSRESPTADSVYKYNIFRSTFHSKSTLSEPQKNSAEGNSHKYDILKKNLPKKSVIKNEKVNGGKKLLNSNKSGAAFSQGKSLTLPQTCNREKIYTCSECGKAFGKQSILNRHWRIHTGEKPYECRECGKTFSHGSSLTRHLISHSGEKPYKCIECGKAFSHVSSLTNHQSTHTGEKPYECMNCGKSFSRVSHLIEHLRIHTQEKLYECRICGKAFIHRSSLIHHQKIHTGEKPYECRECGKAFCCSSHLTRHQRIHTMEKQYECNKCLKVFSSLSFLVQHQSIHTEEKPFECQKCRKSFNQLESLNMHLRNHIRLKPYECSICGKAFSHRSSLLQHHRIHTGEKPYECIKCGKTFSCSSNLTVHQRIHTGEKPYKCNECGKAFSKGSNLTAHQRVHNGEKPNSVVSVEKPLDHMNHYTCERSYRRETV
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of phosphoserine (P-Ser).
Sequence:
MQIQCFESITQKYPQFPTALLANEEPIQNGEPFILYGTKLDITKLEKFQQKCGQNFQIFDVWMVAKNIIVLLKGQWFSDFIKFTHDVEVDIAKLDFSPKLSQAGLLVMDMDSTAIQIECIDEIAKLAGVGELVSAITESAMRGELDFEQSLRCRVGTLKGAPESILQQVRENLPLMSGLVETIQTLQKYGWKTAIASGGFTYFADYLKALLQLDFAASNQFDIEDGKLTGLVKGDVVDAQYKAKTLQHLLEEYGIDSRHSIAIGDGANDLAMMNVAGLGVAFHAKPKVQPQAQIVVNFADLTALLCLLSANDRI
The following text describes a protein:
Function:
During fertilization, required on male (minus) gametes for their fusion with female (plus) gametes. Required for membrane fusion, but not for the initial adhesion between gametes. Inserts (via its extracellular domain) into lipid membranes (in vitro). Probably initiates the fusion of gamete cell membranes by inserting its extracellular domain into the cell membrane of a female gamete.
Miscellaneous:
MISCELLANEOUS: HAP2/GCS1 family members mediate membrane fusion between gametes in a broad range of eukaryotes, ranging from algae and higher plants to protozoans and cnidaria, suggesting they are derived from an ancestral gamete fusogen. They function similar to viral fusogens, by inserting part of their extracellular domain into the lipid bilayer of an adjoining cell.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell projection. Cytoplasmic vesicle membrane. Note=In male gametes, detected both in cytoplasmic vesicles and on cell projections called mating structures at the cell membrane.
Domain:
Both the cytoplasmic and the extracellular domain are required for normal trafficking to the cell surface, and thus for fertilization. The extracellular domain can insert itself into lipid membranes, probably as a trimer. The extracellular domain has structural similarity to class II viral fusion proteins.
Sequence:
MCRAIAVALIVYLAQHYILAHAEVIASGRLEKCVVDGVTEELDCQEKVVVTLTVGNGQSLQTEALEFSLSCLNSPDGRCPCSCSAADPTCACRDLAAPLRVSLTKSPLWASYPLQYLSSFNWKPLEVILRPSNKVCKDGDWEDSPTCGWFSQGGVRVADSQGFCCECSSSQVWDDTFGSSKERTRANLDCDFWSDPLDILIGRKPVSAHCLTFDPQWYSGYELGAASLQFEIAITVEVPTAPSPTTATTSATPRTNNSSSANSTNSTNSPAPQFLSPPAPSTREVLHLGPSVPLASSASRLLSAKLLGDLAMYTQLPAISNQVLMVPQPPAAAAATGSPLDATLATNRSAWMLLDKTMLSMDGLACDKVGTGFSAFRYQPSGCGRAPQACLSGQLKDLWEADLARIADGRVPLYMITRFTGGSDTTLQSFSGGPLSFALPVTSHSQSLVTLSVAADGVRLVTNRSPGKITGAAVCRFAGTSCGGFEAVAARGYIYVNITNTGRLDSDYTLTVSNCSSNVRPIEARTLAVRAGSAASLDPPMELYVEDQAAAAARTCTVSLYDSVGAVTDSLTLSFYTNATQLVVKPSGGYNGTGDGAGVKRNGTDCSTACTNPIDVLCFVTKKCWSKFGRLLGIIGGALVGLGLLAVALKFGWLASLAASCCGGGGGAAAGGAGGGMGLGTGGGGGCFGGGQQQQQLPPAASHAMSPPQQQQRSHAEVAAGAAVAGAGAAGAAAAVLGAKHGGGGGGARGKQQHADTRHLQDRDSRAIDGGASIGSSSAGGSSSLSSYSQPREAGGRLLQPPAAAVFVPEGGGGGAAGDEGARAQSSDWDARGRSPRVADEHGSPRQRYDGVRQSPYMVSANPYDGWYDGGSGGGGGGGGGGYGREAPPPQGPPPHPVGAPPPPPRRRSLWERMWLQRPGGGGGGGGGGGGGGGGGSGGGVDQHGGRSCADAARRGGGGPGGMRGVEGLMSNGGRPNGPHPHAPPPPPPPQQQQQQQRQRRSFLESLTAMMTLPWGGGREEEAGGDRRGGGRGGAAAAHGGRGAGGGRGHPPSIGSPPPGPLQPPEYGPQGGQARRWGAGGGRGGVGGDGGGGGVGAAAYVQLSTGGRGGGGGGGRGRGGGREGPTWHNPVYDWQAPPK
The following text describes a protein:
Function:
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
Subcellular Localization:
Nucleus.
Sequence:
MGVSGLLPLLKPIQAAAHISEFKGQRLAVDGFAWLHKAAFGSAEDLALNRPTDRPQQWVMRKVEFLKRCGVDVLIVFDGGALPSKRGTDEKRHALRDQAHKEALALMSRGRRSEAVNLFQKATRITQEMVHQLTELLKSQRIPFVVAPYEADAQLVYLEKAGYATGIISEDSDLVVYGAQMLVTKLDPSGGCVTVDGSRISSCSDLELGSEVPLEYLRYMAILSGCDYCDGVPNVGPKRAARYIRRWQTPEAIIKALRMDGYNSSPDFLERFHAANFTFLYQRVYCPEARRLVHLNEPEDELDEKVDFHIGAEIPQGLARAIATGLVHPRTHKTFPANKTAKPTNLRGFFAPKNEYTGDVKRLPEQLRRKKPVVLVAKPVDLAVRTASAENMLSPTRTKTSPALTSSHFFSIPSSPDQAEKENKPFNFNTMLSSEPDRSDDDIEESSIVFGTPNKDTTLPQTPVTCAKRKSTLFEEFGYNASTPKRRVVTPTGSSGVAKKPTITPTITPSSTPQARPKKSAISPLTVQRVPGSSQSNLMRFAYKAN
The following text describes a protein:
Function:
Involved in chromosome segregation. During meiotic prophase, connects telomeres to the spindle pole body by forming a bridge between the telomere protein rap1 and the spindle pole body protein sad1.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Chromosome, telomere. Note=Colocalizes with the telomere cluster during the 'horsetail' stage and then disappears before the first meiotic division.
Sequence:
MFQGKCAFFDETVPSALIALWQLHNGEAKFLAEGYENFDYAFSMHLRKHVRLPNYKSVQCRSPWWIAEQVAVSRSKSYVSEPVIHLNVMEPLYVDHRIRSVYLQPLPSTLSFLNGELP
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide. Its role in saliva is unknown.
Subcellular Localization:
Secreted.
Sequence:
MRVLVSVVSLFFLGIQALSEWSYSGDDGLEESRWPEKYPSCGGERQSPIDVKRREVHFSSSLLPLHMVNYEEEGLELSMTNNGHTVQITLPNTMSMRDSDGTVYRTKQMHFHWGGRDSEISGSEHTIDGMRHAIEIHLVHFNEKYETYEKAVDQPDGLAVMAVLVKVEDYTENDYYSTFISELENVKYTGQTTTLRNVNIRNMLPGDIRHYYTYQGSLTTPPCTENVKWFVFQDSATISKAQAERIENAVMDHHNQTIRNGYRRTQPLHNRVVEANFPYSPDEVSKNHFYMHEKISHGLKLKKIKKKRNHSH
The following text describes a protein:
Function:
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MATPETRHKPNILITGSPGTGKSTLSQQVAEKLGFEFIEISKEVRENNLQGEFDEQYSCHVLDEDKLLDHISDRMDSDDGGIVVDYHGCDLFPERWFDVVVVLRCATEKLYDRLQSRGYSKFKIKENVECEIFGTLLEEAKESYKEEIVHELQSETPDQMEENLDRICEWAAAFKNSGGQGPQSDEMDQ
The following text describes a protein:
Function:
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSHGKRHGLGIETKGRWLYKGEWTHGFKGRYGTRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVGPDSPTLLANATRPARPARGLFPRSRTSVGSQRSRVSFLKSDLSSGSDAASTGSLGEGAEGADDAAPFEADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGRREEGKYRHNVLVKGTKRRVLPLKSSKVRQKVEHGVEGAQRAAAIARQKAEIALSRTSHAKAKAEAAEQAAVAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEILENSESLLEPPDRSPGAAGLPERPRESPQLHERETPRPEGGPPSPAGTPPQPKRPRPGASSKDGLLSPGAWNGESGPEGSRPATPSEGAGRRSPARPAAEHMAIEALQAPPAPSREPEVALYRGYHSYAVRTAPPAPPPFDDEPEPDAAGSDSAPASPASAPASPASAAAPDSPAKLEPKPIVPKAEPRAKARKTEARGLTKGGAKKKARKEAAAAAEAEVEIEEVPNTVLICMVILLNIGLAILFVHLLT
The following text describes a protein:
Function:
Required for nuclear migration.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Localizes to the plus ends of microtubules.
Sequence:
MTDIDTPASPLTPNSKAHLEVIAYNQYLQAKEQIQQLEHELTEFQESSKELELELEQELAESDKRQAKLEDRISALESEVTEWRKKALDAHKEAASTQQALQREVSSLRDAHKLVKERLRETENANDDIEQRERITCSTLEDIQTRYNEALENVAILEAELAAKDVLIGEHHRAKEEIKDLTEELEHTRKKLAIRDQELEDANKRIMNPPPATNHNATTHRRAVSGTAQVSAEGYLTPLTSTGAKPLSSSRSMQFIHGLQSQMRSLESRVAHVKSSLPKPTTPKRAKSSASAVSGASTIKSSPSMALLTRKLSEADDVVSLSPSRSTSSLEDLCTPSPSPQVARRDMSGGGSRLDLRADPRLNGRPKTQQPRPSYNSALATAKPLDPIEGSPTSLEGRNRTRSASPTKKLSSLSLNAPSLPQSQARVNIPALMRPASPIKQPSPPKPAPGSKFADVYGRRR
The following text describes a protein:
Function:
Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity). Transcriptional activator that promotes leaf senescence by up-regulating senescence-associated genes in response to developmental and stress-induced senescence signals. Functions in salt and oxidative stress-responsive signaling pathways. Binds to the promoter of NAC029/NAP and NAC059/ORS1 genes.
Subcellular Localization:
Membrane; Single-pass membrane protein. Nucleus. Note=Localized primarily in plasma membrane or endoplasmic reticulum membrane as dormant form and, upon specific stress or signal, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP).
Domain:
The NAC domain includes a DNA binding domain and a dimerization domain.
Sequence:
MVDSSRDSCFKAGKFSAPGFRFHPTDEELVVYYLKRKICCKKLRVNAIGVVDVYKVDPSELPGLSMLKTGDRQWFFFTPRNRKYPNAARSSRGTATGYWKATGKDRVIEYNSRSVGLKKTLVFYRGRAPNGERTDWVMHEYTMDEEELGRCKNAKEYYALYKLYKKSGAGPKNGEQYGAPFQEEEWVDSDSEDADSVAVPDYPVVRYENGPCVDDTKFCNPVKLQLEDIEKLLNEIPDAPGVNQRQFDEFVGVPQGNSAEVIQSTLLNNSSGEYIDPRTNGMFLPNGQLYNRDSSFQSHLNSFEATSGMAPLLDNEKEEYIEMNDLLIPELGASSTEKSTEFLNHGEFGDVNEYDQLFNDISVFQGTSTDLSCLSNFTNNTSGQRQQLLYEQFQYQTPENQLNNYMHPSTTLNQFTDNMWFKDDQAALYVQPPQSSSGAFTSQSTGVMPESMNPTMSVNPQYKEGQNGGGTRSQFSSALWELLESIPSTPASACEGPLNQTFVRMSSFSRIRFNGTSVTSRKVTVAKKRISNRGFLLLSIMGALCAIFWVFKATVGVMGRPLLS
The following text describes a protein:
Function:
Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current. Plays a role in shifting voltage dependencies of activation and inactivation of the channel. May modulate G protein inhibition. May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. Involved in membrane targeting of the alpha-1 subunit CACNA1C.
Subcellular Localization:
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MKASWIRLLKRATGNRVKNNIGGSADSYTSRPSDSDVSLEEDKETLRREAERQAQAQLDKAKSKPVAFAVRTNVGYSASSEDDVPVPGTGISFDPKDFLHVKEKFNNDWWIGRLVKEGCDIGFIPSPVKLESSRLRQEQRAKQGRFYSSKSGANSSSSLGDIVSNSRKSTPPSSAKQWQKSTEHAPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRITITRVAADISLAKRSVLNNPSKHAIIERSNTRSNLAEVQSEIERIFELARTLQLVVLDADTINHPSQLGKTCLAPIIVYIKITSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPSELFDIILDENQLEDACEHMADYLELYWKSTHPPSGAPSTPLLDKLSAVTAAAVACKEQLTNTQPKGTGSDQHADRAAADRTSFYEDYHHHHHPQQQHYQTQKQESFEEEEEEEDDDEEENTDERHDNRDQQDHHKNQHSSSTRTERHHHHRHHHHHHHHRHHHSRTGRTLSKQETLESTETQTHSQPQQEEEQESVQPNHHRHHHHHHRHHHRNEKEKEHDHNERNSRQRGKQKSQREHHHHERRKHYIEQ
The following text describes a protein:
Function:
Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases, including fatty acid desaturases.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MANLISFHDVAKHKCKNDCWILIHGKVYDISTFMDEHPGGDNVLLAVTGKDASIDFEDVNHSKDAKELMKKYCIGDVDQSTVPVTQQYIPPWEKESTAAETTKEESGKKLLIYLIPLLILGVAFALRFYNNK
The following text describes a protein:
Function:
Serine/threonine protein kinase required for spore wall development.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MESKEISIRSRTPPSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFVKNITITNLKSDVDLIKQKKVQERYTKVPKYPLQNRLYKNSNTVRGKEFWNFESTRLSTTQISKEELSPITQDSPTSSLNMESPYLLHGQTVTPITNPSSSSFRKCTQPVFELDSGMDIDSGCPNAQAETEIVPLSNHNKKHKKNDIQALKIEKFDYLKNIVSHILNRMYDRARDDETRKYVNEMLKQFIKTEANVPGFNEVFIEEISLRIEAIKKGFV
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
Miscellaneous:
MISCELLANEOUS: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSPRQLNFLSAFSLSVAIAVVYHQAWGIAVAQPILPSEAVETGVISNGISINLFQAFVLGFIQGATEFLPISSTAHLKAVPMALGWGDPGVAFTAVIQLGSIGAVFWYFWEDLTGIAKGIIKAVQTRQYDSLEFKLGLGIGLGTIPIVFFGLLMKLLVQDLDNSFFRSLSTIAIASIVMALLLALAEKLGTHRRPFEKLRWQDGLIMGTAQALALIPGVSRSGSTLTAGLFINLERAAAARFSFLLGIPAITIAGLVELKGLLDKNLSNDAILPLIVGTISSAVFSYLAIAWLIKFLQKRSTWIFVWYRLIFGVVILTALGMGFGT
The following text describes a protein:
Function:
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
Sequence:
MSDYEPLRLHVPEPTGRPGCKTDFSYLHLSPAGEVRKPPVDVEPAETSDLAYSLVRVLDDDGHAVGPWNPQLSNEQLLRGMRAMLKTRLFDARMLTAQRQKKLSFYMQCLGEEAIATAHTLALRDGDMCFPTYRQQGILITREYPLVDMICQLLSNEADPLKGRQLPIMYSSKEAGFFSISGNLATQFIQAVGWGMASAIKGDTRIASAWIGDGATAESDFHTALTFAHVYRAPVILNVVNNQWAISTFQAIAGGEGTTFANRGVGCGIASLRVDGNDFLAVYAASEWAAERARRNLGPSLIEWVTYRAGPHSTSDDPSKYRPADDWTNFPLGDPIARLKRHMIGLGIWSEEQHEATHKALEAEVLAAQKQAESHGTLIDGRVPSAASMFEDVYAELPEHLRRQRQELGV
The following text describes a protein:
Function:
Adhesion G-protein coupled receptor (aGPCR) for androgen hormone 5alpha-dihydrotestosterone (5alpha-DHT), also named 17beta-hydroxy-5alpha-androstan-3-one, the most potent hormone among androgens. Also activated by methenolone drug. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRD1 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Acts as a 5alpha-DHT receptor in muscle cells, thereby increasing intracellular cyclic AMP (cAMP) levels and enhancing muscle strength.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKELPALSCHWVWLFWSFCGFQVCGTQPRAQEHPGFEVLASASHYWPLENVEGIRELQDTTGDIMEGKVNKSIYLKEEKGVTFLYYGRYKSSCISNPAQCGPEGVSFSFFWKTQGEQTRPAPYAYGGQVVSDGFKVCFSGGKGSVELYTRDNSMTWKATFNPPGPYWTHVLFTWKSKEGLKVYVNGTLSTSDPSGKVSHAYGDPHINLVIGCEHDWTKRYENGAFDEFIIWERALTPYEIKMYFTAAVGKYPPLSSTPPAMPTAHPVMPTDAYHPIITNLTEERKHFQRPRTVLRYLQNVSLSLPNKSLSEETALNLTETFLRTVGEVLLLPSWIHVSEDNAVTLGLVDTIDTVMGHISSNLQPREPHISLTGSSSMAEFSVAKVLPPALSAPHYRFPAHGHSYIEIPREALHSQAWTTIVGLLYHTMHYYLNNIPPASTEIPEAANCRDCLLSVASHLISLEVSPPPTLSQNLSGSPLITVHLRHKLTQKQYVDATNESNRLFLYCAFLNFSSGEGVWSSQGCALTEGNLTYSVCHCTHLTNFAILMQVVPLKLTLGHQVALSSISYVGCSLSVLCLAATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFSMEPGTVPCQVLAVLLHYFFLTAFAWMLVEGLHLYSMVIKVFGSEDSKHLYYYGIGWGCPLLICIISVSSSMDSYGTGDSCWLSVESGAIWAFVGPALLVIVVNIVILVAVTRVISHISTDSYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVSDRALVFQYMFAILNSSQGLFIFLFHCLLNSEVRAAFKHKMKVWSLTSSSAHTANTKPSSSDTVNGTRPGTASTKLSPWDKSSHSAHRVDLSAV
The following text describes a protein:
Function:
Component of the nuclear tRNA export machinery that my collect tRNA from the nuclear tRNA export receptors of the aminoacylation-dependent export and may deliver aminoacylated tRNAs to the translation machinery pathway at the nuclear pore complex.
Miscellaneous:
MISCELLANEOUS: Present with 1360 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MNFSSIFKSISNFQFPYTIEETAITETALWQCFDGTRKADSLPVTVFKAKRSPENESLILNAVHKSKILKIPGLCTVLETFDSDPQSTFIVTERVVPFPWDNLGSLSQNKFGVELGISQLLATLGFLKNFVLGTLSKDSVFINIKGEWVLFGLELCSSKEGLSAFEFASRARSYYNIIGSQLPCEDPNTIDSMGLGLLIKSLMAPSCLPKDWIVNVNMISDGKITIENFRKRLENTETWRSNPLINFYQELRELHIKDPQGKLVVMSNLENLYLESREIFRNLTPGMIENFIIPELCEIIKLLMTQSISSAASPIGMNFNASHKLVPFLAIVLDLTSETNTFPVGFNDLITQSFKLPDRQVRFLLLIYLPKLIGPLSKSEISSRIYPHFIQGLTDSDATLRLQTLKTIPCIVSCLTERQLNNELLRFLAKTQVDSDVEIRTWTVIIISKISTILSTSVGNRSNILATAFTKSLKDPQVKPRLAALYGLEKSIELFDVNTIANKILTVIAPGLLDKSPIVRGRAKILFEEYLEKLEKEAQLIQTNDSTADSEDVKDIDFENYGCDEEDMNKEDNLLAAQFLNNLRLNSPSATTPSNITESEIDSAQDGSGWDDLSDTDGFITNGTTESFDETTNPVTTASTPKLFGKPIKINKSWNDELNDDGWIQDESGPSKVPQKHTRPQNSTLAKSIAPSSRLSIKKKKTTILAPRNIASNSTVTTKSSLSNKTARSKPISSIRGSVTKKGNVDGWDDDGDSDSWDTNW
The following text describes a protein:
Function:
Specifically methylates the guanosine in position 1516 of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MSHVSICLLSEAGADPGALSILADRWGLVSDDQAVMALVLTAERLELRKRDEPKLGGIYVDFVSGTQAHRRKFGGGRGEAVAKAVGIKKGYLPRVVDATAGLGRDAFVLAALGCQVQMLERNPVVAALLDDGLRRGYLDAEIGPWLRERLTLLHASSLTALVAIEPRPEVVYLDPMYPHRQKSALVKKEMRVFQSLVGADNDADGLLAPARALATKRVVVKRPDYAEPLAGVAAQAAVVTKSHRFDIYPSSVTPPR