lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MENYINKILFLLIFFIFHLNSTKNYKKTYRYIISFLLYFINILYAQKIWGNGKKQIRCCFIKNLYNNNRGIFRLLDNDIKRKYNIIYLKKKNNGFANNEHAFVKNTVFIERGQNDENKINYVQGNFDENVKDIKYLSDMQKNFIYLLERNNNLLVHAKTSSGKTTICLYYLILKFFYNCEFIFKEDIEREEYIMKNDYIDRNIYESKNKSRKYFNQNKYRFIPYSEKYSEISDIKEYTNLMIENKCKTKLKKDEKVLILCPSKELCVQVAQNILSFMNNKNESLIKLFIDKDYKNENKEKQNFKEEECINKMEHIQINECDDHYMHHTSKHSVNNNKDTMDIEENKLYMLEHDNLNEDNSSSKVKKKNKINDNNNNSNNNSNNNSNNNNNNNSRSQLHHMVNLKGVRYLIGTPTCFRSYLLNLDKENLKNFLQSIKYIFYDEIDKLLPSVSKRSLLKNKKNIKSKTAYLILETLMYINKKNLIFIGCSSTLNRELHRKIFKLLCLNKNNAKKKIYILREKKNLLDNKENDGMTRIDNITNLIDIPIKNNEKKKNISEKKLSSSNEHIDDNNNSNNIINDEQEEIENNEQYNLNYYLNEENAFQKYIIKVKLPSTIYHFYHLMTDETYENKIKEIHKIIETFKNQKILILIKNGYSLIQLKKYLEMNNIFAVLLHEKLQISLRYNNDNINNMCEHYEDIKDLKSIPNDDKHTYINKYPIIISSFDSIRGFHINNLDMVLLCNKPKNVNEYIHLCGRVGRRKKIGYSVTLENDKNINIMNNWFNNIKVYFNKLSLKSDPVIDEKINNELENQEKNHLNYVASCILDELQENT
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MKCSIFPLLFPKIDSPHPQKSLLLFSPFYFPKPFLPYPDSLYLAPNFPKLATLYISSKGCSRRRSRTSRSSGTGLELAVWDKKMVHAQFNWYWYHVPTFAPYKVEGLFLPLILAHGSSKQSAKTILIVLQSLTPYGQSVFRILAEYQLSHPNDEGMAIDNLYSISRERFLVSSQQHELPHKDGLRPSKNRKEKERQAMENSSSSSELQKLIEAIKISEVVKGRTELIAKLADLHLSEQFDVKSATCIAVAVYLFVKREKNILDNLETLLQEKDI
The following text describes a protein:
Function:
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
Subcellular Localization:
Chromosome, centromere, kinetochore.
Sequence:
MAAASEERMAEEGGGGHGDGGSCSAAGSAQRQPPAPPSQAPPPGSQAPAAPALAPDHLPQNNTLVALPIVAIENILSFMSYDEISQLRLVCKRMDLVCQRMLNQGFLKVERFHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLMGSPPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVRTNGAGVTVLRREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAELERKLREVMESAVGTSSGSGQSEESPRKRRKATEAIDSLRKSKRLRNRK
The following text describes a protein:
Function:
Involved in the processing of polycistronic chloroplast psbB-psbT-psbH-petB-petD transcript. Could bind RNA.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MNILRPPTSSSSSSFPPYPKPVSLTPPVSFTLIHNPINLCSINPPFTNAGRPIFQRSASGTANSSAEDLSSFLGSPSEAYSTHNDQELLFLLRNRKTDEAWAKYVQSTHLPGPTCLSRLVSQLSYQSKPESLTRAQSILTRLRNERQLHRLDANSLGLLAMAAAKSGQTLYAVSVIKSMIRSGYLPHVKAWTAAVASLSASGDDGPEESIKLFIAITRRVKRFGDQSLVGQSRPDTAAFNAVLNACANLGDTDKYWKLFEEMSEWDCEPDVLTYNVMIKLCARVGRKELIVFVLERIIDKGIKVCMTTMHSLVAAYVGFGDLRTAERIVQAMREKRRDLCKVLRECNAEDLKEKEEEEAEDDEDAFEDDEDSGYSARDEVSEEGVVDVFKKLLPNSVDPSGEPPLLPKVFAPDSRIYTTLMKGYMKNGRVADTARMLEAMRRQDDRNSHPDEVTYTTVVSAFVNAGLMDRARQVLAEMARMGVPANRITYNVLLKGYCKQLQIDRAEDLLREMTEDAGIEPDVVSYNIIIDGCILIDDSAGALAFFNEMRTRGIAPTKISYTTLMKAFAMSGQPKLANRVFDEMMNDPRVKVDLIAWNMLVEGYCRLGLIEDAQRVVSRMKENGFYPNVATYGSLANGVSQARKPGDALLLWKEIKERCAVKKKEAPSDSSSDPAPPMLKPDEGLLDTLADICVRAAFFKKALEIIACMEENGIPPNKTKYKKIYVEMHSRMFTSKHASQARIDRRVERKRAAEAFKFWLGLPNSYYGSEWKLGPRED
The following text describes a protein:
Function:
Spindle pole body component that binds calmodulin. Overexpression of pcp1 causes the formation of supernumerary SPB-like structures and disrupts both mitotic spindle assembly and chromosome segregation.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Sequence:
MSERDFNTQSPKFKDENANSVISQSDFLGKSLKNNNDDYSDFRGSYLNDKSSFQTPLRNGSYQPKGSLEFTPLLQSSNKNSDKYNGSLGDKGSFDPNSYGLSAISKQATQEALSISQGNDSYDVSKLTDLSKNSEIDHTDGELPANAALTLREQEKVLEKVSRENFGLRIKIVCLEKRLESMAPEQIKEAVKDNVELHAERANLQLQLKRTESLLQKSEDKNFKLEEKVDYLSKVNDVEQSQNVKVFTERIRFLENALEKVQREKDSLSTEMEEDKSNKEVDYEYEIRQLQNRLDELSEELDVAQDLLTEKEDEIATLKRQIEEKENSSSAFENEENSSYVHLQEDYAILQAKCDEFADRIQVLTADLEKEKENQIMHESEASIGLTDSMQVHTLQEQLHKANEEIEFLHDQISRMNEEGKNFEDIMLQFRSLEEERDVLESKLQTLEDDNNSLRLMTSSLGNQIESLRTQNREIDEEKNHLRLLASKNSDKALAETNIRLQEVTKELETLRMKNSNDLNEIHDLREENEGLTLKIDSITKEKDRLINELEQRIKSYEVNVSELNGTIDEYRNKLKDKEETYNEVMNAFQYKDNDLRRFHESINKLQDREKELTSNLEKKNLVISSLRETVAMLEKERESIKKYLSGNAKDLDNTNLMEILNDKISVLQRQLTDVKDELDVSEEEREEAIVAGQKLSASFELMSNEKQALELKYSSLKNELINAQNLLDRREEELSELSKKLFEERKIRSGSNDDIEKNKEINVLNSELADKLAQIRHLESDKMELDKLVHHLNRGIEEANIEENAVKKRLCLLMGCDYSSVSILQIVSQIEHFVNQQIQTIRSLKQELRHDFVQFSGKKEQELSRSFEKFGLGTETKHDILAQRNRNVSEKMNDLENAAQKFFSSPDRKNGYLYPSEHTSKIEYLEKTIEDLKLALQDELKNRNLLMDDISSYNKQTTKLQEKIKWLERERSILIDELESYRSNQFNYQNNLVQDKNELEERLKEIQKELEVYNNHFMKQAELMTSNVTDESQLMLKTLREALQSKTNNIDHLSTILERNRKEYKSLLDDYNQLRARYKNLQSNTPQSTQSGQYESEIKGLSKLTKYLQSKCRREHSLRLDLAFSKKFILMQLTGYETCNKINLRMLQKIGISPDPDLSKKHIKLKSLIIVVCSIERMKRMKNEWLKQAQLKQSLQRAAAKAKTANY
The following text describes a protein:
Function:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Subcellular Localization:
Nucleus.
Sequence:
MDLRVGERGMRPGSDTALLTPLHPPLLLTTFSPQPRTSFSHQQLHQQIRFNMEQRRREQVRHETQQELQQLRHKDKSQQSAVASSLVKQKLQEVILKKQKQAALERTNPAHPVAYRKLGPDPSAPAQPLVSPPSQSSPESSEGTPLRRAASEPNLKVKNKLKKHLNTRKSPLTRKESAPPTVKHRVPDTLDSSPSSSSTPVSGCSSPNDSLPCENGLLPSAGGLSHEAHKMLLRDGTLSSFTIQSPSTLPTITLGLPANSRADGEVSPLKVSRVPMVTAGVSPVFLPISREDQGGQMGPHLPVIILESPGLVHPPLLTVPSLDSVPLQFAHQLERLSPGGVQPHKPLSRTRSEPLPQTLHTHLLQQQHNTQLLERLKQQTHLGKLMSKSSEKPRLHQIPSEDMDSEDGGGTSPSEPAYHNRVRAGSLREAETTSSKSHEEQLQHALILNQSLLWEQQKQLQQLHRQMKTLAVPVLPGGCSGGGGIHRPLSRTQSSPASTSLTLPEKPLNLAAPEISSKPRFTTGLVYDSQMLKHQCACGDNSSHPEHAGRIQSIWSRLQERGLRGQCESIRGRKATLEELQSVHTERHVLLYGTNPLNRLKLDNRKLAGIFSQRMFTMLPCGGVGVDNDTIWNESHTSTASRMAAGSVVELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCYFNSVAIAAKQLQQKLSVSKILIVDWDVHHGNGTQEVFYNDRSVLYISLHRYDDGNFFPGSGSPAEVGSGAGEGFNVNLAWTGGLDPPMGDAEYLAAFRSVVMPIAQEFSPDVVLVSAGFDAAEGNPAPLGGYKVSAKCFGFLTHQLMSLAGGRLILALEGGHDLTAICDASEACVSALLGMQDSMPEDVLLQKPNANAVRSLQTVIQIQSQFWQNVKAHSGTLGLSLLEAQSRDCEETDAVNALASLSVGVMPNKR
The following text describes a protein:
Function:
Negatively regulates the structure and function of the limb apical ectodermal ridge.
Subcellular Localization:
Secreted.
Sequence:
MIPGNRMLMVILLCQVLLGGTNHASLIPETGRKKVAELQGQAGSGRRSAQSHELLRGFETTLLQMFGLRRRPQPSKSAVIPSYMLDLYRLQSGEEEERSLQEISLQYPERSASRANTVRSFHHEEHLESVPGPSEAPRIRFVFNLSSVPDNEVISSEELRLYREQVEEPSAAWERGFHRINIYEVMKPLSERSQAITRLLDTRLVHHNVTRWETFDVSPAVIRWTKDKQPNHGLVIEVTHLHQAQTHQGKHVRISRSLPQGHGGDWAQLRPLLVTFGHDGRGHALTRRARRSPKHHGSRKNKKNCRRHALYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
The following text describes a protein:
Function:
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
Sequence:
MPEKQVAPVISNLEDFANNLPGYLISESPVAVLLDYDGTLAPIADNPAKTKMPVELEAILHKIAKHPKVFLAVISGRGLKDVQKQVNIDGITYAGNHGLEIEYPDGSRHDYELPTEIQKNYTQMVRELKEKVEKNGAWVEDKKVSLTYHYRDTPAALKDQQKQLASEICTKFGFRANQAHEAIEAKPPVNWNKGEAAVYILKQKFGDNWSQKVSVVFAGDDTTDEDAMRVLRGLGRSFRISADAQIQTYADFRLPKQAVMTDLLKWIANVYVS
The following text describes a protein:
Function:
Catalyzes the addition of a phosphoethanolamine moiety to the osmoregulated periplasmic glucan (OPG) backbone.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTAAFTAILLLLWRTLPRVQKVLVGVSSLVAACYFPFAQAYGAPNFNTLLALHSTNMEESTEILTIFPWYSYLVGLFIFALGVIAIRRKKENEKARWNTFDSLCLVFSVATFFVAPVQNLAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQTYVVVIGESARRDALGAFGGHWDNTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVDGKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEVYFLKEGNFEADKNTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTQGKYETFVQSKETSCYLYTMTQTDDLLRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVPFMVISSDDKAHRVIKARRSANDFLGFFSQWTGIKAKEINIKYPFISEKKAGPIYITNFQLQKVDYNHLGTDIFDPKP
The following text describes a protein:
Function:
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
Subcellular Localization:
Cytoplasm.
Domain:
The MATH/TRAF domain binds to receptor cytoplasmic domains.
Sequence:
MKLGRDIPIYKLIIIKNESIENNLKEISFSDNFKCQICEGLLISSLIPNRMKALQCINGHCFCLTCWESILEIKSECPTCRIQIQSMNTLSNNLFIIKSISESIKIHCPNYLNFDNSNNFNGCKEIITIDEIDRHESKCEFRFIKCSINNQCNEIIRFNERDKHESQCDFIIQKCTHCDESVQMKQMQGHILFECLKVLITCQHCSLQFTRLKLQNHIENHCKEIKIECPFKSLKIIYNNNNNDNDNNDSDENNSNQSLSSSSLSSSIIPLSPCNELMKRSELSKHFIRNHQYHNELVSIVLKKQENKIKKLETIIQQNNVNQNFEISIIKHSNSLTRDSFYKENKKKDKLIQDLMKRVLILEHQQQQNQIQNQIQNQIQKLSNKSIFTTTTTTTSTSDKNNNNNNNNNNNNNNNNEDEEDDDNIKNNDNQGNLKSLREMFNTISNFKDDENEQQQIQQQQQLPFTSFGPLSVQQQNNPTKQFNQLSQPQTQPQSQSQSQSLFGEWSPITINQNQNTPSNPFSIFSGTSL
The following text describes a protein:
Function:
Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
FASFESSMALNIYFCGSIRGGRQDVAVYQKIVQKLQKYGTVLTEHVSHAALSEKVPGEDAVLEGDKAIHDRDVDWLKQADVIVAEVTQPSLGVGYELGRAVAMDKRVLCLFRPSSGRVLSAMIRGAADGSRFQVRDYAEEEAETTVEDYFTA
The following text describes a protein:
Function:
Component of the MSS1-MTO1 complex that catalyzes the 5-carboxymethylaminomethyluridine (cmnm(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs.
Sequence:
MLGGGVGFAASAAHGTRQATRHSRRQFATASPALPLAGPSRSDLHFDVVIVGAGHAGCEAAAGSARTGARTLLVTTNKHSIGELSCNPSLGGVGKGTLVREVDALGGLCGIIGDRAGIQFRMLNKSKGPAVHGPRAQIDRSLYRQHMQEALRQYPNLTISEAKVHGLQLDWSNRASSHHGNQGEGEKAKAVVRGIVTTNGDSISCSQVILATGTFLSADIHLGLESRSAGRMLPLPSINDDPASDGLSQSLARAGFKLGRLKTGTPARIAASSVRLGSPWQIGSKVDPRLEVIHGDAAPAAFSFLHDAPDIAPARQVECWGTHTTPLTHEIVRQNLDKSIHIKETVRGPRYCPSIESKVIRFKEKQAHPVWLEPEGLPGTNDGSVLYPNGLSCTLPSEQQVELLRSIPGLECAEMIRAGYGVEYDHVDPRELRHSLETKRIEGLWLAGQINGTTGYEEAAAQGCVAGLNAGLKVNGLDPLSIGRSGGYIGTMIDDLVMQGVEEPYRMFSSRSEYRMTLRADNADKRLTPLLRAAYSAAVGEQRWQRFCATQADMDQALALLKANRMSPHGWMKHGFHCSGDSHERSGLDMLKQPRLGIRDLIPVIPALANLGTMVMDRVEIEAKYMPHLERQAQEIEAFNKETQLRFPEGFNFGSVPGLNSQLREKLELLRPTSLAALKSIPGCTPSNYATLWRYAVQLEDSERSPRTSM
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MGGCISVANTSYLRKSSLVQPITRQETKTPKFVRPARVLKDSAGGDIFKHYKFGKELGRGEFGVTYQCQNIETGEKVACKKMSKSRLIAEIDVEDVRREVTIMRHMPVHPNIVSYKDVYEDKDAIYLLMELCEGGELFDRIVTKGHYTERAAAVVIKTILEVVQVCHTHGVMHRDLKPENFLYAHKGENASLKAIDFGLSVSFEHGQRFREVVGSPYYMAPEVLKRNYGEEIDVWSAGVILYILLCGVPPFWAGSVDAQQVVLEPVARVRFSQRAISKAEGRGGSWGSEMASTKTSHDGLEYSNRMSGPGGLNVLYGKFLVTETEEGIAQAIIKGDINFERDPWPRVSEDAINIIRGMLDQNPYDRLTVEEVLENKWIQNAHKVPNIPLGEHVRARIQQFSLMNKFKRKVIRVVAENLPDEQVHGLKQMFDDMDKDKNGSLTFEELKDGLCTIGEQPLADPDVQMLMEAADLDENGVLNCEEFMIVAVHLKRISNDDHLRQAFHHFDKDNNGYIEYDELRESLFEEHQNSYNEKLVHDIIHDADLDKDGRISYPEFAAMMTTGMDWKMASRQYSRVMLNAISVKMFKGETIEEEEDIEIS
The following text describes a protein:
Function:
Plays a role in the flagellum-specific transport system.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Sequence:
MDGVPIFKRIPFIALCVILLTASLAAAAEPLALPSVSIGVGKATKPGDVSVVLQIFFLMTVLSLAPGLLMMTTSFTRIAVVLSFLRHAIGTQQAPPNQIIIALSLFLTFFVMAPVWQQVNTQAIQPYRAAQITQDEALKRAVAPMRKFMLSQTREKDLALFLNLSKLPRPRTADDIPTLTLIPAFMISELRTAFQIGFLIFIPFLVVDMVVASVLMSMGMMMLPPVMISLPFKILLFVLVDGWGLVIGSLIKSFG
The following text describes a protein:
Function:
Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.
Miscellaneous:
MISCELLANEOUS: Present with 1750 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSVEEKKRRLEELKDQNVVLGLAIQRSRLSVKRLKLEYGVLLERLESRIELDPELNCEDPLPTLASFKQELLTKPFRKSKTKRHKVKERDPNMPKRPTNAYLLYCEMNKERIRQNGSLDVTRDLAEGWKNLNEQDRKPYYKLYSEDRERYQMEMEIYNKKISNIDADDDKEENEQKIKNNEEGSSTKVADSKGGEDGSLVSSN
The following text describes a protein:
Function:
Orphan receptor.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDLKTVLSLPRYPGEFLHPVVYACTAVMLLCLLASFVTYIVHQSAIRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLDTDQPPYPRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEGGRGIRPGTPPAHDAPGASVLQNEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWACCPPRKDAHPALDANGAALGRAACLHSPGLGQPRGFAHPPGPCKMTNLQAAQGHASCLSPATPCCAKMHCEPLTADEAHVHLQEEGAFGHDPHLHGCLQGRTKPPYFSRHPAEEPEYAYHIPSSLDGSPRSSRTDSPPSSLDGPAGTHTLACCTQGDPFPMVTQPEGSDGSPALYSCPTQPGREAALGPGHLEMLRRTQSLPFGGPSQNGLPKGKLLEGLPFGTDGTGNIRTGPWKNETTV
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MTIIAISIMNVVIGIAILGVILRKKIMPNQKFQRIFILGVQGILIVLSGIMLIGCEGTDIINRISPYINMVTVYSNNVNINIGYSIDGISAIFIFLTIILILSCNLISIRVIKEKTEQKFQIMLLLTEILIINFFAATDLVQLYIVYEATLIPMVIMIGVWGSRTEKKIAAFQILIYTLIGSIFMLMSIGILYSTLGTTDYIMIREYIDVLPENVRKLIFIGFFIGFAVKIPIAPLHLWLLRAHVEAPTAGSVLLAGILLKLGGYGYIRYNIGLFPDLCEYYFPIIGGICLISILYTGIATLTQLDVKRIVAYSSISHMNVIVLGLFSGVLQGIEGGIILMIGHGVVSGGLFLCIGVIYDRCKTRIVYAYNNLVHVMPIMAILFFLLVLGNIAFPITSNFVGELLIFIGLIKKNIIIAFFSALSMIVTAIYSFWLYNRIFFVNEIIKREANEVISSKGQIVADMNALFLIEDVMKKKEERGIDDIGQPKEVKKEQLIYSDVNIFEFTSISLMVIMMIIIGMKPSVVEGFIAINCLELISK
The following text describes a protein:
Function:
Involved in budding and cytokinesis.
Sequence:
MSLSAAANKISDNDFQNIGPAPRPPSSNSQGRTCYNQTQPITKLMSQLDLTSASHLGTSTSKKKSGWVSYKDDGILSFIWQKRYLMLHDSYVALYKNDKQNDDAILKIPLTSIISVSRTQLKQYCFELVRCSDRNSVSSGSSSSLNVSSDSNSKKSIYIATKTESDLHSWLDAIFAKCPLLSGVSSPTNFTHKVHVGFDPETGSFVGMPTNWEKLLKHSRITGEDWNNNSAAVIQVLQFYQEYNGAGNPTNTLDKPQSGETSSSQKSLPNSYNDNKLRNNSVNSKSSSGVSSSMVSQRKTSQPPNTKSPVSLGSGSLPPINTKLPTSQSNIPRHLQNVPNQQYPKMRNGHSPTNGQFPRGPMHPNNSQRSLQQQQQQQQQQKQQHQQYPYHHQGPSPSPSPSPSPLNPYRPHHNMINPYSKQPQSPLSSQSTQNQAIPRYAQNSSPTAAHFQPQRTAPKPPISAPRAPYPSNQNATSNTHVQPVAPKNDQSTPQTMRQAPKRPDADVAQPGGVAKPKKPARPTMSTAEIMSKLKKVTVNADPSQCFKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFFNMACDPKDLTSLLEWKE
The following text describes a protein:
Function:
Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. Directly binds to a guanine-rich region of the PCNA promoter and up-regulates its expression which in turn induces cell transformation and tumor formation. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.
Miscellaneous:
MISCELLANEOUS: The helix-loop-helix and basic motifs form a Spz1 specific bHLH different from the classical one.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSDTDNSAEMPARCPSPNPAPGAKQEPPNSGITISLLEIGSLPTVCYHSFPPPKNSICPVEKRGRVQKFSNLLKDVKDVLKNIAGVEEKSTVGEPFDDAYIPEDLSELNVRGVEKKNKIRFKDDLFIHFDPEREQNTMKQMLLKNQSAKNMVPKFARDLCNAEETRGFDGMLLSVKRPRNGSLHLRGEYRKLRNNMEQLLQEADHWSKQHNELSELMRSYQECQNETQETTDKDRACLQNQPNNGLSTKQKLEEQVKKLSHDTHALHLIAALLENECQVLQQRVDILKDFHLHEAGLGHEKPLQMSCEQDKKCPKLAEADKTDAFKHTTRATEGTIRKPKILRSPDVCFTKKARNNRFNARVAKKSLVGKRRTVSSFR
The following text describes a protein:
Function:
Structural component of the gap junctions.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MTKAAVTSFTDPLKRIRGLESGTEKLLHNTTIAILVFLFILLASKPMFGSPIVCQVPKDWPSSSVDYFTDICYYGQREKVDIQHRISRAGGRGTVTVNLTTGTSEFYMWVPLVPILLVALCLLPAFFWKFVGLDCFNGMDIVSFLEFYEQTDDPGERLVEMEGWRRRKLAAQLNKWIMAKRNFFCGLSQTMIIYVLMKWFRTILFIAQFWIIADVFGDGNFFWGYADLARIANGDSINPLKGSFTLISGCRVQRLAMSIGFYRSYTNAHSAVARCMLSANFLNAKAFLVLYWWFLLVSFISLCSAIHYTIILLVPQYRRHEFKSMIRTEDHFIERYGEPHPNLHLGKEAPLEYLVEHLGNDGFLVVEMVYDMLHHYECDRFTEHIWMHIIVHNGEEDFEDDEIENKKIKIVDEMEMDGAGDRNSGGIDKKETNDWSSSAGTSKNKDSTSKVSLSASQPSMMMSESDEEPMISPAVFTSLSS
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. Acts as an endoribonuclease (mRNA interferase) on single-strand mRNA, cleaving between the first and second bases in the sequence UCGCU. Overexpression in M.smegmatis but not E.coli inhibits growth, this effect is neutralized by coexpression with cognate toxin MazE4; Residues 29-56 inhibit ssDNA cleavage by DNA topoisomerase. This fragment does not have mRNA cleavage activity but it inhibits growth upon overexpression in M.smegmatis.
Sequence:
MNAPLRGQVYRCDLGYGAKPWLIVSNNARNRHTADVVAVRLTTTRRTIPTWVAMGPSDPLTGYVNADNIETLGKDELGDYLGEVTPATMNKINTALATALGLPWP
The following text describes a protein:
Function:
Could be required for the biogenesis of a putative fimbria.
Subcellular Localization:
Periplasm.
Sequence:
MLRHITFTVFITTSMNTLATGMVPETSVLLVDEKRGEASINIKNTDDHPSLLYTTIVDLPESNKSIRLIPTQPVIRVEAGQVQQVRFLLQATVPLQSEELKRVTFEGIPPKDDKSSRVTVSIRQDLPVLIHPASLPEERETWKFLEWRKNGDQIEISNPSNYVVRMTLQFKTLPSGKTGAINKTYFLPHTSTTTALTNATDTKVEFYPASRYGYRGNKYVTDLK
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
EKPNHGRHKRGRKQSAMPPRTHGRRPRTHGRRQRRRGPPRTHGRRRSWPRRRLALAQIGWISISTPPSRRTRPWRKLAMYMEELVQVEDWDLRRFELEDPQLPAGVFAGAEGPAAVRAAPAGQAFHHQFAGGPRVFDSSAAAAAAAQANANRVVLAPPAGGGIDMQELADHVAAMEDLQFFAAAEANANNQLAAPARGGPRAFNQTTRHGQPVGAKRADAVISARQAVLGDGSSPVVLAGMEEEHDNRWYESIRREAQRMEQMEEEPGLYEVSYFQTQLPRPQQEPREEPLNYNSTEGLGFIASDLDPDEPGPSMVRPARVPPLADDEVPKFKCGICMETLPILDLFHGMQCEHRFCVECMATYIEGRIHDCEVPIPCPDPACRELGEDSLVLHPEECKKSIDFAAFVSWGYRLTESAIPQNRRAYCPNRQCGVMLEATGGKTPVMAFCPVCSHPMCATCGVDWSKDDSGQHDCFEGPSAALVKKLAEERRWKQCPRCKMLVEKIYGCNVMRCRYGARSSPVYLPQVNHFIYAN
The following text describes a protein:
Function:
DNA helicase loader protein that participates in viral DNA replication, recombination, and repair. At the fork, required for loading of the replicative helicase onto DNA protected by the ssDNA-binding protein. Coordinates simultaneous synthesis of leading- and lagging-strands.
Sequence:
MIKLRMPAGGERYIDGKSVYKLYLMIKQHMNGKYDVIKYNWCMRVSDAAYQKRRDKYFFQKLSEKYKLKELALIFISNLVANQDAWIGDISDADALVFYREYIGRLKQIKFKFEEDIRNIYYFSKKVEVSAFKEIFEYNPKVQSSYIFKLLQSNIISFETFILLDSFLNIIDKHDEQTDNLVWNNYSIKLKAYRKILNIDSQKAKNVFIETVKSCKY
The following text describes a protein:
Function:
Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. May act as a negative regulator of normal cell cycle progression.
Sequence:
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKLREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREEYSDKGKVGHWSRSPLRPPRERFEMGDNRKPVKEEKVEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEEETGSNSEEASEQSAEEVSDEEMSEDEDRENENHILVVPESRFDRDSGDSEEGEEEVGEGTPQSSAPTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLSGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSDIDQINKIFKDLGTPSEKIWPGYNDLPAVKKMTFSEYPYNNLRKRFGALLSDQGFDLMNKFLTYYPGRRINAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
The following text describes a protein:
Function:
Acts as a guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
Subcellular Localization:
Cytoplasm.
Sequence:
MAPRGIADRPSPHPGASARRHLSARWRCRSGAELEPRPPRPRWACPAAAPPPCSRCAQVGSRLARSRLSVSASPPLPGTVELGTPFAWEFCGRLGSAVTSQRAGPAAAMVAKDYPFYLTVKRANCSLEVPPASSPAKDAEEPSNKRVKPLSRVTSLANLIPPVKATPLKRFGQTLQRSISFRSESRPDILTPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSKVLCCHGELKNNRGAKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEEPFLNATTGSREPEGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHVESNV
The following text describes a protein:
Function:
Essential for male fertility. Required for sperm flagellum biogenesis. Also required for acrosome biogenesis. Required for the attachment of developing acrosomes to the nucleus during spermiogenesis and may be involved in the transport of fibrous sheath components.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton. Note=Localizes to the sperm flagellum, manchette and the perinuclear region of the sperm head.
Sequence:
MSSNLSPTLNSGDKVKDGSIKEDRPYKIFFRDLFLFKENEMEAKKTEKLMNHNMKVYQKTTFSSRMKSRSYLSQLAFYPKRGGRSFEKFGPGPAPISRFLEGSDTKRTVHEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKLAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLKEYMKYGFFLLQLSPKHWQIQQALKRAQASKSKANIILPKILARLSLHSSKKEGILEEFGGTAILSEDASRERDSQGKPSRILTRTSEKIKSNLTESFGSEDSLEFLLDDEMDFDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEEMLKANCVREEEKAAELQLRSRLFSFGEFNSDAQEILIDSLSKKITEVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPRENVEAIERMKQKERRQKFRDEKMREKQRHQEERLKAALEKAVAQPKKKLGRRLVYHSKPPSANKQQLPLVNETKTKAQEEEYFFT
The following text describes a protein:
Function:
Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing. Has an ATP-independent activity. Specifically cleaves peptides in the range of 5 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. Degrades the transit peptides of mitochondrial proteins after their cleavage. Also degrades other unstructured peptides.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MFRQSKTIITKLTNLSFQGSWRSRGSSAVEKALKYTVGQKIHNFTVKEVTAVPDLFLTAVKLSHDATGAQYLHAARDDSNNLFSVLFRTTPMDSTGVPHILEHTVLCGSQRFPCRDPFFKMLNRSLSTFMNAFTASDYTMYPFSTQNAKDFQNLLSVYLDAVFFPCLRELDFWQEGWRLEHENPTDPSSPLVFKGVVFNEMKGVFSDNERLYAQHLQNKLLPDHTYSVVSGGEPLAIPELTWEQLKHFHATHYHPSNARFFTYGDLPLEQHLQQIEEEAMSKFERTEPNTAVPPQTPWDKPRMDHVSCRPDALAPDPVKQNTLCMSFLLGDITDTFEMFTLSLLSSLMMSGPNSPFYKALIEPKIGSDFSSSAGFDGSTRQASFTIGLQGMAEDDTETVKHIIAQTIDDIIASGFEEEQIEALLHKIEIQMKHQSTSFGLALASYIASLWNHDGDPVQLLKISESVSRFRQCLKENPRYLQEKVQHYFKNNTHQLTLSMSPDERFLEKQAEAEEQKLQQKIQILSSEDRKDIYEKGLQLLAVQSTTQDASCLPALKVSDIEPIIPYTPVQPGAAGGVPVQYCEQPTNGMVYFRAMSNINSLPEDLKIYVPLFCSVITKMGSGMLDYRQQAQRIELKTGGLSVSPQIIPDTEDLDLYEQGIILSSSCLERNLPDMFQLWSDLFNSPRFDDEERLRVLVMMSAQELSNGISYSGHMYAMTRAARSLTPTADLQESFSGMDQVKFMKRIAEMTDLTSILRKLPRIKRHLFNPENMRCALNATPQKMPDVAAEVERFIGNIAGNRKERKPVRPSVVERALGPEAGAAATRKLISEAHFKPCQMKTYFQLPFNVNFVSECVRTVPFTHADYASLCILGRMMTAKFLHGEIREKGGAYGGGARMGGGGLFSFYSYRDPNSTQTLSAFRGGVEWARAGKFTQQDIDEAKLSVFSAVDAPVAPSDKGLGRFLNGITDEMKQAHRERLFAVTERNLIDVAGRYLGIGQQTCGVAILGPENESIRKDPSWVVK
The following text describes a protein:
Function:
May act as a transcription factor for cell pluripotency and differentiation in the embryo.
Subcellular Localization:
Nucleus.
Sequence:
ESKVEDDPKGKEESFSLESDVDYSSDDNLPGQTAHKEEDPGHALEETPQSGGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGEPSRNPKIVVPIPVHVSRFAIRS
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MEDNDSLELSLGLACGGSSNKSKPSSSSDHSGGASKNHSNSGNYVRDGVGGSLNVSNGSFNGFLTSNNDNQNHSEIGQQKHENFWTSLGNNSSTRQSIGASSPMYRELWPSSDKSKPSVNIVNENSVLGKHKISFDDITAQKKLNKEDSLNRENEDVAESEADGPPSWLIHRSAENNNFRPTRPDERFFLANPHHLGQSGHGDEVPFFIRPASSNRNGVSLMPIVDIQNSSGRNGQIFRPHHPVTQMMPLSKDKQQQCLHPPQLNGQNSSPLMSFGYASSQLPRLERGSWLLGPPFQNGMSSIDRNPNNARPIPPLTPGENLKTSHEGASMEFENRKIFENGREVIIVEEVLKHPTSETRERSSNSNKIIRQNGIPNSQPTDTNIIRPGVASGLIFGGNGSCPDLPWVSTTGSGPNGKTISGVTYKYNKTQVNIVCACHGLHLSPEEFVHHANLDDAPRLDAESNPGNNAASSHN