lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
Miscellaneous:
MISCELLANEOUS: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MTIRNVTRGLRCTLAFRTLPNALPVQASLCRVDCALLSTTCARRKSGLKADGSRADQAEAGASQSLDKQSRTLDSVRDDTLSDPYPLPFSPDIVELNSVKTRVEAGLESKWSGVNLASSQQTLNHIDAPMRVPGRDSEARETKIARLIYQTRKRGTLETDLLLSTFAKKELKNLPDAELDEFDRLLDEPDWDIFYWCTQRKPIPARWAHSFNTAGKLGHRLVAHTRNDEKAVRWMPEL
The following text describes a protein:
Function:
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MRRPGTSGRRPLLLVLLLPLFAAATSAASPSPSPSQVIEVPGVPSRPASVAVCRCCPGQTSRRSRCIRAFCRVRSCQPKKCAGPQRCLNPVPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAIPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA
The following text describes a protein:
Function:
Probable transporter. Does not act in the transport of monocarboxylic acids across the plasma membrane.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCIICTSLSTIALMLTRTTHQGLRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHLVMAILCWAMWIPCKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNELHLNVKLSHMSKCLFRYKQLPRRV
The following text describes a protein:
Function:
Catalyzes the decarboxylation of 4'-phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis. Involved in salt and osmotic tolerance, and light-regulated plant growth. Trimerization of HAL3 recruits and activates the E3 ubiquitin-protein ligase HIP1, which leads to the degradation of cell cycle suppressors, resulting in enhancement of cell division and plant growth. HAL3 function in cell division seems to be independent from its PPC decarboxylase activity. Acts as a positive regulator of flowering by binding to HD1 in the dark.
Miscellaneous:
MISCELLANEOUS: Seedlings over-expressing HAL3 show enhanced growth rate under normal light/dark cycles, enhanced salt tolerance and Na(+)/K(+) homeostasis. Enhanced growth is due to increased cell number of root meristematic zone and root cap.
Subcellular Localization:
Nucleus.
Sequence:
MTTSESVQETLGLDFPHPSKPRVLLAASGSVAAIKFESLCRSFSEWAEVRAVATKASLHFIDRTSLPSNIILYTDDDEWSTWKKIGDEVLHIELRKWADIMVIAPLSANTLAKIAGGLCDNLLTCIVRAWDYSKPLFVAPAMNTFMWNNPFTSRHLETINLLGISLVPPITKRLACGDYGNGAMAEPSVIDSTVRLACKRQPLNTNSSPVVPAGRNLPSS
The following text describes a protein:
Function:
ABC-type transporter; part of the gene cluster that mediates the biosynthesis of the isoquinoline alkaloids fumisoquin A, fumisoquin B and fumisoquin C; as well as small amounts of fumipyrrole as a shunt metabolite. The products of the cluster lead to a brown coloration and are important for growth and conidiation. FsqE possibly plays a role of self-protection (Probable).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTPPQMVSQLDDARLDERQRAILDRQLHGLGGETKQRKNVFAYATVSDRIVLSVSSICAVLAGALNPLVPVIYGLLVSVYDGFAAGTVSASELRSKTATFSLYYVYLSIGLFAFTYVATVGFYYTGERMARALRTTYLAAILRQNMAFFDLLGPGEITSRIMSDMGTVQEAVTSKLAVMLTAIATFCAAFVVAFIMYWKTALIISPFFVIMIVTETLGGAYMVRHHKRAMELYSQAAGIAEEAIAAIKHVTAFGIQTLLSQRYLSVLEQAAKADRKAENMVAGMIAWMNAMPNLIYALAFWAGSIYLTRGQMSVAEVSATTLAVTIGSFAIIRIAPSAQALLSGIAITGEILKSIARRSPQDPLVKEGDEPSTVVGDIVLDRVGLIYPSRDDVDILQDVSLRCAAMKKTAIVGSSGSGKSSILGLVERFYEPTSGTVLLDGRDIQSLNLRWLRRQIALVDQMPVLFNATILENILYGCSDMVSQWSESEQLDRVVQASKKANAHDFISALPDGYHTHVGEKGLQLSGGQRQRVAIARALIRDPKILLLDEATSALDSKSEAMVQEALDAAAEHRTTIIVAHRLSTIQNADHIIVLDHGKVVEEGTHHALVAQNGAYAALVQKQQIGDTHDHKAPDGARLSIEDDDDEDSRYGGNTEYVDEKDIRTEEVALSSAAHDEGTQRDSLKLSALQTIAFIARLSKRDWKVLLFGLANAILAGLTIPVQSVFFAKILTVIGFPPPQYPQLRSEVDFWSGLYVMLTGTTFLFWMGVEIALSYATQKLARRVREVCFRSILVQDMAFFDVPGNSPSALSSVLSKSTNDLAGLGGPVMGGILTFLSTILAGIVLALAIGWKLALVCTATIPIVVACGWLRLQVLSTFDSKVRQSGIESAAYAGELVRTVRTVASLGLEEHALARYEGILAKQAAKSLRSILLASALYAASASVVYLCAALAFWYGGTLIASHEYSTFQVYICFVSLISGSQIAGSIFTYAPDASKAMHASREIQDIMNLKPSINKVAPTGPPPAHEGTEKNQPQQNLSACRVEFEHVSFTYPSRPTRRALDNLHITVEPGQTLALVGQSGSGKSTCVSLLERFYDPDQGRILIDGQDIKLRDVDEYRRDISLVSQETIIFSGTIRDNITVGLAGQEVSDDEILEACKQANILEFVQSLPDGLSTLVGTGGSMLSGGQKQRIAIARAFLRKPKILLLDEATSALDSQSEAIVQEAMDAIRKDRTTIMVAHRLSTVQNADVICVLQDGKLLEIGTHEQLLGKRGKYWEMVSMQSLH
The following text describes a protein:
Function:
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
Subcellular Localization:
Cytoplasm.
Sequence:
MNGWMDGWMDGLDCEPAIGQGWSLSVANPSIPSAPHRVSAGEMGRSGWPAGGGVGSGGSGGPREGAAEAAEGRGGRGDGARPGRRDPRPGAGSGGGAAAERADPPAPPPPRPAAAPPPRRPTGPRPPPAMKAIVQRVTRASVSVGEEQVSAIGRGICVLLGISLEDTQKELEHMVRKILNLRVFEDESGKPWSKSVMDKQYEVLCVSQFTLQCILKGNKPDYHMAMPSEQAKAFYGNFLEQLRKAYKPELIKDGRFGAYMQVHIQNDGPVTIELESPAAAVADPKQLSKLEKQQQRKEKTRAKGPSESSKERSVPRSKDDPSASSGAEGDVSSEREP
The following text describes a protein:
Function:
Involved in vacuolar formation or function (e.g. formation of vacuolar membrane 'bulbs'). Required for amyloplast sedimentation in the endodermis during shoot gravitropism, which are thus acting as statoliths. Particularly important for the negative gravitropism leading to leaf movement observed in darkness.
Subcellular Localization:
Vacuole membrane. Note=Detected in small organelles membranes.
Sequence:
MEDRETHLGTREVNETSPDLLKNTPSNIARLEDVIEQCHGRQKYLAQTRSPSDGSDVRWYFCKVPLAENELAASVPRTDVVGKSEYFRFGMRDSLAIEASFLQREDELLSLWWKEYAECSEGPKLQVNSKKKSIETPSEASVSSSLYEVEEERVGVPVKGGLYEVDLVRRHCFPVYWNGDNRRVLRGHWFARKGGLDWLPIPETVSEQLEVAYRNKVWRRRSFQPSGLFAARIDLQGSSLGLHALFTGEDDTWEAWLNVDPSGFSGIVGYTGNGIKLRRGYAGSYSPKPTQEELRQQKEEEMDDYCSQVPVRHLVFMVHGIGQKGEKSNLVDDVGNFRQITAALAERHLTSHQLSTQRVLFIPCQWRKGLKLSGEAAVDKCTLDGVRRFREMLSATVHDVLYYMSPIYCQAIIDSVSKQLNRLYLKFLKRNPDYVGKISIYGHSLGSVLSYDILCHQHNLSSPFPMDSVYKKFFPDEESPPTPAKADKPCSSHPSSNFEPEKSDQLNNPEKITGQDNNTMAKEPTVLEHHDVIQEDPSLISDSVVANVGLERRGGQEDDHHDSSGAISSQDVPDGADCRTPDSPSCSQEQSWDKESVNSNNEERIKLLQDEVNSLRSKVAQLLSENARILSDEKAKTSVAPKELNNEKVQTEDADAPTSFTPFIKYQKLEFKVDTFFAVGSPLGVFLALRNIRLGIGKGKDYWEEENAIEEMPACRRMFNIFHPYDPVAYRVEPLVCKEYLPERPVIIPYHRGGKRLHIGLQDFREDFAARSQRIMNHFDSVRTRVLTICQSKSADNLDEMEETDDEKDDRSYGSLMIERLTGTRDGRIDHMLQEKTFEHPYLQAIGAHTNYWRDQDTALFIIKHLYRELPDGPNSPTESTEGDDSPKDSSRPHSWIDRREADYDDEELPLTFSDKQITRSFSAEAKKYLKKP
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MIGYEAGEPEVVTSEAERDYPPLDSGLAHYTPRDAAVSQRRDTPRIDAAELHGSSPARHQGTHGGPLEAVLKVPAEPHADMFLYEQPAAGLSSAPAGDDASVDGEPPRVGRDGILHGRGPFFEGAGLDFTSTDQVALESMAAADPAEQPFYVNAKQYYRILKRRYARAKLEENLKISRERRPYLHESRHKHAMRRPRGQGGRFLTAAEIDELKKQELAQSKAKSPAKDTADDRPKSPDTSYPPHKIQPQPPGGAVDKQQVADAAPSRT
The following text describes a protein:
Function:
Rhodanese domain-containing protein required for anchoring ferredoxin--NADP reductase to the thylakoid membranes and sustaining efficient linear electron flow (LEF).
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Sequence:
MAAIVSSAAPTTPTPPRARRPRQAPRNRRLPLGGPAAGLFTTLGLNGSGAALAAPLSYEEMLRLSSDTAGGGGDGFSLPDLGLGGLVDFVAQNPLVVAAGLAVVAVPLAVSQVLGGASKPYETVSVKAAYRRLLEEPDAQLVDIRPLKDAREVGLPDISEAKKKAVAVPYDGEDKNGFLKKLALRFKDPENTTLIILDKFDGNSELVAELVTSNGYKGAFAVKDGAEGPRGWQSSDLPWTAPKKGFSLDFGELFGDGSEGLPVTIGLAAATGLGLLAYTEIETVLQFLGSAAIVQLVASKLVYAEDRKKTLQQIDDFFNKKIAPKELVDEIKEIGQALLPSSGEAKSQPAAATAAAPPAATATAAPVAEPAAPAAATATAAPVAEPAAPAAATATAAPVAEPEAPAAEASTESPPDTTTSSRPLSPFANYPDLKPPASPSPPASEGKTEVKATVVAATESPAEVNSAPVAEAVEESSPPAKPRPLSPYANYPDLKPPASPSPSPP
The following text describes a protein:
Function:
Mitochondrial tRNA N1-methyltransferase involved in mitochondrial tRNA maturation. Component of mitochondrial ribonuclease P, a complex composed of rswl/MRPP1, scu/MRPP2 and mldr/MRPP3., which cleaves tRNA molecules in their 5'-ends. Essential for the structural and functional integrity of mitochondria. Function is essential for pupal development.
Subcellular Localization:
Mitochondrion.
Sequence:
MLKHFARWRLGSQLLKGCAAPVRQASKTSSAENLIAGTEEPQKKFVNPFSQPAPALSNDTISENKEERDKRLKVLQLEADIAHQEGRRVPSLEFFKDHHWEHVLTLPTKSARIKYFGYLWQIEMKKEADQRKKAERAKEAERRVAEMRKEREENTHIIYGLGHTSLFLRIYDTTINHWQNNRLTRAMQFAPKMVLDCSYDEHMNNREATYAAKQLMMCFAENRMNDEPFDLHYCNTQMDSRCMQSLQRYIPTMHNPEFPINLHSKCFTELFPKQNLVYLTPHCREDLVTYNPDDIYIVGAMVDTMNNEPLSLAKAKRLGLRMARLPLDRYLQWGSGSGKSLTLNQMINIMLDLKKTGDWDTALKHVPRRKVVQNEFQPRREKDHWSTGTRARKLNMRIDHLFDFDENRRQATSYATPQNVRQRREGLEFQLDTWATGKQKKKQRQN
The following text describes a protein:
Function:
[Capsid scaffolding protein]: Acts as a scaffold protein by binding major capsid protein in the cytoplasm, inducing the nuclear localization of both proteins. Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid. Autocatalytic cleavage releases the assembly protein, and subsequently abolishes interaction with major capsid protein. Cleavages products are evicted from the capsid before or during DNA packaging; [Assemblin]: Protease that plays an essential role in virion assembly within the nucleus. Catalyzes the cleavage of the assembly protein after formation of the spherical procapsid. By that cleavage, the capsid matures and gains its icosahedral shape. The cleavage sites seem to include -Ala-Ser-, -Ala-Ala-, as well as Ala-Thr bonds. Assemblin and cleavages products are evicted from the capsid before or during DNA packaging; [Assembly protein]: Plays a major role in capsid assembly. Acts as a scaffold protein by binding major capsid protein. Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid. Cleaved by assemblin after capsid completion. The cleavages products are evicted from the capsid before or during DNA packaging.
Subcellular Localization:
[Capsid scaffolding protein]: Host cytoplasm; [Assemblin]: Host nucleus; [Assembly protein]: Host nucleus.
Domain:
Region of interaction between pPR and pAP is called Amino conserved domain (ACD). The region of interaction with major capsid protein is called carboxyl conserved domain (CCD).
Sequence:
MAADAPGDRMEEPLPDRAVPIYVAGFLALYDSGDSGELALDPDTVRAALPPDNPLPINVDHRAGCEVGRVLAVVDDPRGPFFVGLIACVQLERVLETAASAAIFERRGPPLSREERLLYLITNYLPSVSLATKRLGGEAHPDRTLFAHVALCAIGRRLGTIVTYDTGLDAAIAPFRHLSPASREGARRLAAEAELALSGRTWAPGVEALTHTLLSTAVNNMMLRDRWSLVAERRRQAGIAGHTYLQASEKFKMWGAEPVSAPARGYKNGAPESTDIPPGSIAAAPQGDRCPIVRQRGVALSPVLPPMNPVPTSGTPAPAPPGDGSYLWIPASHYNQLVAGHAAPQPQPHSAFGFPAAAGSVAYGPHGAGLSQHYPPHVAHQYPGVLFSGPSPLEAQIAALVGAIAADRQAGGQPAAGDPGVRGSGKRRRYEAGPSESYCDQDEPDADYPYYPGEARGAPRGVDSRRAARHSPGTNETITALMGAVTSLQQELAHMRARTSAPYGMYTPVAHYRPQVGEPEPTTTHPALCPPEAVYRPPPHSAPYGPPQGPASHAPTPPYAPAACPPGPPPPPCPSTQTRAPLPTEPAFPPAATGSQPEASNAEAGALVNASSAAHVDVDTARAADLFVSQMMGAR
The following text describes a protein:
Function:
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.
Sequence:
MADPRPDPDELARRAAQVIADRTGIGEHDVAVVLGSGWLPAVAALGSPTTVLPQAELPGFVPPTAAGHAGELLSVPIGAHRVLVLAGRIHAYEGHDLRYVVHPVRAARAAGAQIMVLTNAAGGLRADLQVGQPVLISDHLNLTARSPLVGGEFVDLTDAYSPRLRELARQSDPQLAEGVYAGLPGPHYETPAEIRMLQTLGADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGEPLSHAEVLAAGAASATRMGALLADVIARF
The following text describes a protein:
Function:
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
Sequence:
MTISTTSSSTSSKTSSEKGDDLKGFSSSSSPASSRSSSATTPEPSSPTVLAAKTIESIDPFQPRKDYNENVLPAIPATEAVQPLTSDANTPDHWIARDERMIRLTGKHPFNSEAPLSELFSKGFLTPQNLFYVRSHGDTPRVTREQAENWKLKVHGLVEQEVELSIKDLKEKFPTVTLPITLVCAGNRRKEQNMVAKGLGFNWGAAGVSTGLFTGVYLADILDYCKPKNPLLSSFPSYDVAVPGRARHVVFEGADELPKGKYGTSQRLNWALDRCKGMLIAWGLNGEDLSPDHGYPLRLVVPGQIGGRMVKWLERIEVSDRESQHHLHFHDNKVLPTEVTADQARSEMHWWYDPKYIINDLNVNAAICSPDHDQVVNVAEPSTSSPQMLPLEGYAYTGGGRRIHRVEISLDDGHSWKCASIHYPEDLYRMYPIQGHEYFGTLDLSATEMSFSWCFWRLDVDVQADIIAKDVKVISVRALDEGLATMPRDMYWNATSMMNSWWFRVAVHREGENGNQIRFEHPTLAGNAPGGWMQRMNEAGLNPRYPQFGEAKAVESCKTDANTLAAAKEAKVDPKAIMIDPSKADTIITAADLAAHGDGEGPEPWFVVHGHVYDGTGFLKDHPGGDQSIRLVAGEDATEDFMAIHSMDAKKMLRDFHLGRLEKQDAAPPAATTEGEVLDLSKPFLDPKKWRATRLVSKQIISPDARIFRFALGSEDQELGLPVGQHVFVRVRSKNARTGETEMVQRAYTPYSGNTQRGFLDILIKVYFPSDAAATSAPAFEGGKMTMLLEKIDVSSPSDDLTIELKGPLGSFTYLGQQQIRWKPASAVRRVRKLAMIAGGSGITPIWSTLKAIADEVLDASNPSSPALDPIQIWIVYGNRTEQDILIREELERLRVALKGNLKVWHVLSNCTPENEANWSMGRGHITANVLRTHLPPPPAKPASEDELEDTLALVCGPPPMEKAVSDGLKQLGWDLQRCVVFF
The following text describes a protein:
Function:
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
Subcellular Localization:
Cytoplasm.
Sequence:
MGYDQLPPGKNPPEDIYVVIEIPQGSAVKYELDKDTGVIFVDRFLFTAMYYPFNYGFVPQTLADDGDPVDVLVISREPVVPGAVMRCRPIGMLEMRDEAGIDTKVIAVPHEKLDPSYSNIKTVDNLPEIVREKIKHFFEHYKELEPGKWVKVENWKGLQDAIEEIKKGIENYKKNKEG
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May be involved in detoxification.
Sequence:
MDLYNMSGSPSTRAVMMTAKAVGVEFNSIQVNTFVGEQLEPWFVKINPQHTIPTLVDNLFVIWETRAIVVYLVEQYGKDDSLYPKDPQKQALINQRLYFDMGTLYDGIAKYFFPLLRTGKPGTQENLEKLNAAFDLLNNFLDGQDYVAGNQLSVADIVILATVSTTEMVDFDLKKFPNVDRWYKNAQKVTPGWDENLARIQSAKKFLAENLIEKL
The following text describes a protein:
Function:
Required for the maintenance of mitochondrial structure. Positive regulator of cell division and endoreduplication but negative regulator of cell expansion in the postembryonic root meristem, thus leading to the promotion of root growth.
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein. Mitochondrion.
Sequence:
MGKWRAVAALLLRNQLLNSSKRLNLSSSPCVSKHPTIGLASRFLNFRHFSAFPSPISIYNNDSDSGSNDAYQNYEFGTEAEEALGKIPIKAYFLSTSIDLKAMQAENLCNVVPPTSRSTNYIALKFSDFTPSGIYSLDERESVSNCKFMVVFQYGSAILFNVDDNDVDRYLDIVRRHASGLLTEMRKDDYAVKEKPLLIEEMKGGPDYIVLKTLDTNSIRIIGSVLGQSIALDYSVSQVNKLVEEFADINRSMAKTGTFTMTRKKLFQLVGKANSNIADVILKVGLFERSEIAWREARYAQIYEYLREEYEISQRFGDLDYKLKFIEHNIHFLQEVMQNRQSDLLEWCIIFLLAIENAIGIYEIVRESAGASL
The following text describes a protein:
Function:
Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.
Sequence:
MLPRPLRLLLDTNPPGGVVLSSFRSRDPEEGGDPGGRAVGGGQEEEEEEEEEASVSIWDEEEDGATFTVTSRQYRPLDPSAPLPPPRSSRRLRAGTLEALVRHLLDARTSGADMTFTPALLATHRAFTSTPALFGLVADRLEALESHPPGELERTTGVAISVLSTWLASHPEDFGSEVKGQLDRLESFLLRTGYAAREGVVGGSADLIRNLRARVDPRAPDLPKPLALPDDSPADPTDVLVFLADHLAEQLTLLDAELFLSLIPSQCLGGLWGHRDRPGHSHLCPSVRATVTQFNKVAGAVVSSVLGATPTGEGPREVTVRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGETTRDSLRIFSSLCQIFSEEDNYSQSRELLMQEVKLQPPVEPHSKKAPRSGSRGGGVVPYLGTFLKDLVMLDAASKDELEVSVCVCVPPSQEFAVLSELLRLQNECRGYDLRPNPDIQQWLQGLQPLTEAQSHRVSCEVEPSGTIDSPAARTLRPALVITQWTEVLGSVGGPTPLVSWDRPTVGGDEVPGTPAPLLTRLAQHMKWPSVSSLDSALESSPSLHSPADPGHLSPPASSPRPSRGHRRSASCGSPLSGGTGEGASRSAGCGGGVSGPGSSDCRIIRVQMELGEDGSVYKSILVTSQDKAPSVISRVLKKNNRDSAVASEFELVQLLPGDRELTIPHSANVFYAMDGASHDFLLRQRRRPSAATSGSHSGPSASGTPPSEGGGGSFPRIKATGRKIARALF
The following text describes a protein:
Function:
Required for chromosome condensation and partitioning.
Subcellular Localization:
Cytoplasm.
Domain:
Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible SMC hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
Sequence:
MYLKAVEINGFKSFGDKVYIDFNRGITSIVGPNGSGKSNILDAVLWVLGEQSYKNIRAKESQDVIFSGGKEKKPATKAEVSLIIDNADRYLDLDNDTVKITRRIHISGENEYLINDTKSRLKEIGTLFLDTGIGKTAYSVIGQGKVERIINSSPKEIKSIIEEAAGIKKLQANRIEAQKNLANIEINLDKVEFILNETRENKNKIEKQAELAQKYIDLRDEKSSLAKGIYITELEQKEKNLSENENIKEKYQTECFELQEKLNKTLERLNTIDLEKEEVKKEKLLIDSRNKELRNIISEKEKEKAVTSERLDNVKKEKLVKEEYILHLDNKIEKKLEEVTESKNKKDEISKNIVEMAAANKEFENKIFNLENIKVEKFDLIENRAKKVRDLELEKQLASNEIENNEKKLKSSQDEVENFKQELEEANKKLLANNKEKDLVHSQLEARKEELTKTEERNEFLVNQLSEISKSINKLSQDIREFEYQEKTSSGKLEALVRMDENNEGFFKGVKEVLNSGISGIDGVLISLINFDEKYEKAVEAAIPGNLQDIIVEDKEVAKKCIAFLTEKKLGRTSFLALDTIKPNRREFKANINGVLGLTADLITADKKYQKVIDFIFGGLLIVENIDIATDILNKNLFSGNIVTLTGELVSSRGRITGGENQKSTINQIFERKKEIKTLEEKVTDLKSKITEGSKKREDLSIKLENYENEVDKIDSLEDSIRKDIDLLKKDFESLSEKSEKLSKDIRSISFNIEDAEKYKTSYQDRINSSFSTIEETEKHIASLKKDIEADENLLKQTISEIDSLNKQFSDTRILFLNNQSTIEQLEKDIHSKEIENVELQEEKEKNSKIVIELSHNIEELETLEEELQSQIEEHTKIYNSENRDIETLNEREQNLSNEERELSKDKSKLETDSLHANDRFEKIVEVIEKIKVDILNINEKLNELVEITAQVIEVEKLKSSKDRLRSLENKINNFGDVNLLAINEFKELKERYDYLARERDDVVKSRKQVMDLIQEIDERIHEDFHTTYQNINENFNKMCDETIRNTEGRLNIINPEDFENCGIEIFVKFKNKKKQPLSLLSGGEKSMVAIAFIMAIFMYKPSPFTFLDEIEAALDEKNTKNLLGKLRDFTDKSQFILITHNKETMKESDSIFGVTMNKEIGISKIVSPDKITKILSENKENN
The following text describes a protein:
Function:
With imt2 and imt3, is required for the synthesis of mannosyl phosphorylinositol ceramide (MIPC). Catalyzes the addition of mannosyl to phosphorylinositol ceramide (IPC). MIPC is essential for cell morphology, cell-surface distribution of ergosterol, localization for plasma-membrane transporters, and lipid-raft-mediated endocytosis of plasma membrane proteins to the vacuole.
Subcellular Localization:
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Sequence:
MGRKCRKLLLKGIPICGVILLILWGYSLYNTLRFMVPGKATEPFTLSLSDVSDDTSAPGEMEKIPRVIHQLWKDENIPERWSNTVNSCRRQHPDENGWQFILWTDEKIMSFMNENYSWFMPVFHSYPYNIQKFDAARYFILYHYGGVYMDLDIGCKKPMDPLLSKATFILPSTEPIGYSNDWFAATPKHPFLYQAIHNLSKFNHRYFTKYPTVFLSAGPLFLSYQFCKYLLTPHEPVRVLPALLYGNGPNSFFSHVTGDSWHGTDAKVFIWIDRNSKSVLFFAFLAAFAILFLCLRVVFKRRRKRGIAASHSQIQELYP
The following text describes a protein:
Function:
Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
Sequence:
MAARLGSVADLIWGTASQDAEIVRRWLQGMSSAAAGRFGFEFHDAEPSALVQHAGGPCGVIAPVQAFLLKHLIYPEGKATVPGGWRTPKDQYGALVSALTTMLLQAAMAPSSPAKDAPVVWPAAGVTVVTAPLDAGDQTLDDFHQHAQIAVLHDQDMIEPHLLSLQASLQHPFAVVALVYSLVLTRGTERLAEDMGVEQDSLISAPFGHCNQALLNLALTGTAVPNVWDGDNDMGGLALRGLPRRSTIGYLTLLESLRYCTCGSYFKNPEFPIWVLGSETHFTLLFSLDSRLVVQDSPRQHASTVFDRHDANANGFLMPEQLPALLDELQLLMEDNEARTRLVSALDRDGLGIVLKPQFLAHFYKAEGENGTPEQFVVYHYNGIAQPGSVVRFVRGQAKAESPTDVGATDVMRILWSKWTKLQVQWDQSPRVT
The following text describes a protein:
Function:
Putative glycosidase. Promotes myogenesis by activating AKT signaling through the maturation and secretion of IGF2.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Nucleus membrane; Single-pass type II membrane protein.
Sequence:
MPQNPQEKNQAYLRRCPGSHPGPKSPEAVAAAAMYTFLPDNFSPTKPKPSKELKPLLGSAVLGLLLVLAAVVAWSYYSASLRKAERLRAELLDLNRGGFSIRNQKGEQVFRLAFRSGALDLDSCSREGALLGCSRTADGRPLHFFIQTVRPKDTVMCYRVRWEEAVPGRAVEHAMFLGDAGAHWYGGAEMKTQHWPIRLDGQQEPQPFVTSDVYSSNAFGGILERYWLSSRAAAIKVNDSVPFHLGWNSTERSLRLQARYHDTPYKPPASYTSAPELSYRVCVGSDVTSIHKYMVRRYFNKPSRVPAPEAFRYPIWSTWVLYGRAVDQDKVLRFAQQIRQHRFNSSHLEIDDMYTPAYGDFDFDKTKFPNATDMFRRLQDAGFRVTLWVHPFVNYNSSCFGEGVERELFVREPTGRLPALVRWWNGIGAVLDFTHPKARDWFQGHLRRLRSRYAVASFKFDAGEVSYLPQDFSTYRPLSDPNIWSRRYTEMALPFFSLAEVRVGYQSQNISCFFRLVDRDSVWGYDLGLRSLIPAVLTVSMLGYPFILPDMVGGNAVPGRTTSNGDVPERELYVRWLEVAAFMPAMQFSIPPWRYDAEVVAIAHKFTALRASLVAPLLLELAGEVTDTGDPIVRPLWWIAPGDETAHRIDSQFLIGDTLLVAPVLEPGKQERDVYLPAGKWRSYKGELFDKTPVLLTDYPVDLDEIAYFIWAS
The following text describes a protein:
Function:
Hydrolyzes acetyl esters in homogalacturonan regions of pectin. In type I primary cell wall, galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions. Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MVMATRSLQLFCLIVCSLAIIKTESATDLDFYEVKKTIVKNAVSKGAVCLDGSPPAYHFEPGFGEGVENWFVQLSGGAWCTSVEACKDRSRDNKVGSTTTMGPYTFQGIYSKNQSANPDFYNWNKVLVRYCDGGAFTGDVEYVDPATNLHFRGARIFEAVMEDVLAKGLKNAKNAILAGSSAGGYPAMLYCDRFRSLLPNTPRVKCFVDAGYFIHAKNQKQARGFEDIYNTLVTLHGSAKTLPKSCTSKMKPLLCFFPESMQQNIKTPLFIAMSAFDIFQINTTVEPHLHDVIENGTCTTSQNKAFREFRSEFLSTLPKPNNPKLRGVFIDSVNHHTSLLIRWSPENATMINNLSLPKAFGDWYFDRKYWYVIDEHDLPISKKHEHELRKDGGQTHKEDNH
The following text describes a protein:
Function:
Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.
Sequence:
MVATSAQRAAVRMLRGWRTSVVRTSTSVTSTSILPLSTRLRCSDLPHQPLMAVQRRLKSKRSSAQYIDPNAADADDVPVIKTKGKASKNNRAAQPTSRGARTKRGDAEQSSDVEYKTSTRNQHLPDEAFDFDAISSHMSRAVERFRSTASTLVGSFGRADPSLLDSIKVEYPAGSSSKALHPLRDFATVGVRDGALIVTAFDADMVKHIERAIYASNLNLTPQTQAGGEENVLRVAVPQPTTESRQALVKDLTKICENARVSIRDARHKAQKQIKSDIDRKVVGKSEGDRESKKVEAETKKWSTQVDHLFEKIKATLLLV