lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MPPGRWYAVHPAQAKASRERGRLQMVKKEEEDEDYTSVPATRPQTLNRPGQELFRQLFRQLRYHESSGPLETLSRLRELCRWWLRPDVLSKAQILELLVLEQFLSILPGELRTWVQLHHPESGGEAVALLEELQRDFDGSPWRDPAPAQSPDVHWMGTGALQATQIWPPASPLRSGSALGDHLQPPCEIGVRDFLAGQPDSPAAQVPTLSQREGCPGDQVTAQPQEALTFKDVEVTFSQDEWGWLDASQRNLYRDVMLENYGNIASLMGPFTKPALISWLETREPWVLNVQGAQPEGNPGADVAGGELHMKTKKFNLKHEPLKEAVTLAIPSGCHGSANISKETGLREPSEQKSRLKEPCGNPVQVKVEKEETDSSHGTGKDCEDSGRSNSLHLKHTMYLRGPRRKQSLKHGCGRHFRGSSYHCEYKEYGKGLRCLLGGFSLHQRIHAGLKGKPKDAHGKDFSLSSHHQHAQNRHVVGMSYKCGDCGRTFSHSSHLTCHQRLHTQEKPFKCRACGKAFRWSSNRARHEKIHTGLKPYKCNLCDKAFRRMSAYRLHQETHAKQKCLESNQYEEALSCGSEFERHLGDQTGEKLFDCSQCRKSFHCKSYILEHQRIHTQEKPYKCTKCRKTFRWRSNFTRHMRLHQEETFYDQDECREDFRQTPNDSQPQRAPTVENSFSCQQCGKTFTQKKSLIDHQRSHSGEKSYWCSECAKEFTHRSTFVVHKKQHTFKREPEDAPPLSQDRAFQVPQSSHTTEEPCTCSQCGRAFRNHSILLIHQRVHTREKPYKCMECGKSFRWSSNLSQHQRVHSLEKPYMYREREDPPNLQSQILTGEKPFWCQECGKTFTRKRSLIDHKGIHSGEKRYKCNLCGKSYDRNHRLVNHQRIHTKERPFKCQWCGKDFIGRHTLCVHQRKHTSVAQSECSVAGLSSRQDSRVSLQELKPREEKPLEDCKEACDQRSGLTGLEDVPIGGKCHKCSTCGKTFNKSSQLISHKRFHTRERPFKCRECGKTFRWSSNLARHMKSHVRD
The following text describes a protein:
Function:
Catalyzes the cyclization of 2-methylgeranyl diphosphate (2-MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate.
Miscellaneous:
MISCELLANEOUS: 2-MIB is a volatile organic compound that has an unusually low odor threshold. Together with geosmin, methylisoborneol is responsible for the characteristic smell of moist soil as well as unpleasant taste and odor episodes associated with public water supplies and contamination of various foodstuffs, including fish, wine, and beer.
Sequence:
MPVPELPPPRSSLPEAVTRFGASVLGAVAARAHDSEATVGGPSGGRPLPSPPAGLSFGPPSPAAPPTDVPAPEAPGWGADLERLLCGPHGLGTAGLRLTPGKERPVPATAREGRPIPGLYHHPVPEPDEARVEEVSRRIKAWALDEVSLYPEEWEEQFDGFSVGRYMVGCHPDAPTVDHLMLATRLMVAENAVDDCYCEDHGGSPVGLGERLLLAHTALDPLYTAREYQPGWAASLHADAPRRAYRSAMDYFVRAAGPSQADRLRHDMARLHLGYLAEAAWAQQDQVPEVWEYLAMRQFNNFRPCPTITDTVGGYELPADLHAQAAMQKVIALASNATTIVNDLYSYTKELAAPGRHLNLPVVIAEREGLSDQDAYLKSVEIHNELMHAFESEAAALAAACPVPSVQRFLRGVAAWVDGNHHWHRSNTYRYSLPDFW
The following text describes a protein:
Function:
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MTQLLATANEHALTQANDFIKANNKGRALNILRDLLIERSQWHSSLEQVMSLYVSLCAENLDYQSLRDGIHHYKASITSQKEFSLAPFENILKEITSPIEAKIDEMKESLDKTSAAEEQTDLITLIDPQQTVLFSYMKYLFEAYKSMIEVLTRPNIKFEHAKFDHSKFDPILLKISIQALNYCLKYQRKPDFMVLTETFRSSIEALFKAPSLDTVNTHIEIRFHQLSVAISLGLYNIAYKSIEDINIMIFSLLAKPKPVVLATYFQKLAQVYWITNAHLLHAYALYKHFFYNKNYNMNFSPEDTQLYSSVLLVAALSSPIQENNTNNSLLQFDSQSQRAMGLASLLSLQSIPRRETFLQDVRKVTGDVYPELADLFSIFEKKSSPLMFAKLLEPKIKFIESHAQLSQYLKPFLRVVFTKITLQVSKVYEVIKIEEFIKLIPFYNKGQIELYLLEAIKRKLIGARIDHKAGVVRFGHYDFDSAKISDQLSNIASGVGKALKMVEPEKKEQQHNRVKKEVYVKIINSLNDEHRRILARKEIIEKKKIYMEQQERIKKQKEQEETLKRAQEKALRDQQRIQEDLERREIEQQQQQQQVSQLDQTINAVDKAKVEMRAKVAKISKQLYILERAYREEELPVVEKLQEVKKVEDKEYFEKTQNDYLQTHKSIHDRNIAEKNRLNRIVSDYQTFTQHILEERKKQLPALQQEQEKRFQEFLRQQEQEVAERKAQKEATRKAAAEAKAREEEEKRRREEEERAAREKEEQERKNAPYVPPSRKTFDDDSGSGRPFGDRGNRDNWGDDRRGGFGRDDRRSGDRDNWGSRRGGDDDRRSGERDNWGSRRDDAPPQRGDGEDSWKRDDAPPQRREGGVFGREERRGDDRRGGYGREERRGTDNWGRRDEAPPRRDDNEGWGRRDDAPPRPREGGAFGNIRRGDEDRRGGNDSWGRRDDAPPRPTNDSDNWRRDDTPPQRREGGGGGAFGNTRRGDDDRRGGDSWRRGEKKDDKKKDDDGWQTVGPKRGNKF
The following text describes a protein:
Function:
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MDRLGSFSNDPFDKPPCRGCSSYLMEPYIKCAECGPPPFLLCLQCFTRGFEYKKHQSDHTYEIMTSDFPVLDPTWTAQEEMALLEAVMDCGFGNWQDVANQMCTKSKEECEKHYMKHFINNPLFASTLLNLKQAEEARTADTAIPFQSTDDPPRPTFDSLLSRDMAGYMPARADFIEEFDNYAEWDLRDIDFVEDDSDILHALKIAVVDIYHSRLKERQRRKKIIRDHGLINLRKFQILERRYPKEVQDLYETMRRFARIVGPVEHDKFIESHALEFELRREIKRLQEYRTAGITNFCSARTYDHLKKSREEERLKRTMLSEVLHYIQDSSACQQWLRRQADIDSGLSSSMPVASNSGRRSAPPLNLTGLPGTEKLNEKEKELCQMVRLVPGAYLEYKSALMNECNKQGGLRLAQARALIKIDVNKTRKIYDFLIREGYITKA
The following text describes a protein:
Function:
Positive regulator of URA1 and URA3 expression.
Subcellular Localization:
Nucleus.
Sequence:
MKQKKFNSKKSNRTDLSKRGDSPNIGISKSRTACKRCRLKKIKCDQEFPSCKRCAKLEVPCVSLDPATGKDVPRSYVFFLEDRLAVMMRVLKEYGVDPTKIRGNIPATSDDEPFDLKKYSSVSSLGEEGILPHNGLLADYLVQKGNSMASSAITSKSMASPQTINVQRKEFLVNSKKQDGSALLPETGSPMTSDARAEELRRCNKEISALGTMRESSFNSFLGDSSGISFAKLVFTATNFRQDSGDDVLDEDIKQREQKYNGYAEAENNPHFDPLELPPRHAAEVMISRFFVDTNSQLPLLHRELFLKKYFEPIYGPWNPNIALASDQTGINSAFEIPITSAFSAHTEPKRENVTEKIDVCSSVDVPWYDTWETSQKVNMRPIVELPTKFHIPYFFLNIIFAIGHATQVLKSDITTVATYKRRATKYIASLFSSSDRLEALAGTLLMVIYSIMRPNVPGVWYTMGSVLRLTVDLGLHSEKINKNYDAFTREIRRRLFWCVYSLDRQICSYFGRPFGIPEESITTRYPSLLDDSFITLTNREIDDYSDLPSPNPSSKVIALAMYKIRRIQASIVRILYAPGAELPRRFMDLESWRIETYNELERWFQVDVPKNFEMMNCKFNSIWFDLNYHYSKSILYGLSPKFPTLNDTAFKIVLDSTKGTIDVFYNLCVNKKIGYTWVAVHNMFMTGMTYLYVNFYSKNNINDCQEKVSEYTEKVLIVLKNLIGFCESAKTCYTSYKILSSVVIKLKFMQINDAKGIFSDSNPLTSQANRMSSYDKKTNVLGFDDGTFDNKVFNRTNFEEKAPFDIPLDEFFTELEKHSNVSQFNTLDVSEGNQVINESASTNTSSALNCQSYTNNQDIMDILFQVTSGSVWDEFFVRSGNGNEGESSYDISKGKNSESGGIF
The following text describes a protein:
Function:
Involved in eye morphogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MRNLPCLGTAGGSGLGGIAGKPSPTMEAVEASTASHRHSTSSYFATTYYHLTDDECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYPCHMTLRPPPMAPAHHHIVPGDGGRPAGVGLGSGQSANLGASCSGSGYEVLSAYALPPPPMASSSAADSSFSAASSASANVTPHHTIAQESCPSPCSSASHFGVAHSSGFSSDPISPAVSSYAHMSYNYASSANTMTPSSASGTSAHVAPGKQQFFASCFYSPWV
The following text describes a protein:
Function:
Acts as a magnesium transporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDGTETRQRRLDSCGKPGELGLPHPLSTGGLPVASEDGALRAPESQSVTPKPLETEPSRETTWSIGLQVTVPFMFAGLGLSWAGMLLDYFQHWPVFVEVKDLLTLVPPLVGLKGNLEMTLASRLSTAANTGQIDDPQE
The following text describes a protein:
Function:
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin (By similarity).
Subcellular Localization:
Secreted.
Domain:
The fibrinogen-like domain (FBG) contains calcium-binding sites that may be involved in carbohydrate binding.
Sequence:
MALGSAALFVLTLTVHAAGTCPELKVLDLEGYKQLTILQGCPGLPGAAGPKGEAGAKGDRGESGLPGIPGKEGPTGPKGNQGEKGIRGEKGDSGPSQSCATGPRTCKELLTQGHFLTGWYTIYLPDCRPLTVLCDMDTDGGGWTVFQRRLDGSVDFFRDWTSYKRGFGSQLGEFWLGNDNIHALTTQGTSELRVDLSDFEGKHDFAKYSSFQIQGEAEKYKLILGNFLGGGAGDSLTPHNNRLFSTKDQDNDGSTSSCAMGYHGAWWYSQCHTSNLNGLYLRGPHKSYANGVNWKSWRGYNYSCKVSEMKVRLI
The following text describes a protein:
Function:
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Sequence:
MNKLCQQSYISMETPIGIVSLIHTSRGIKEINLDKSVNHDPDIVNHNMTNYSVSIESSSGPLTECAQDSIRWVEMFFDPKSNSYLKVPAIDNEIVKKDNFTGRVLRSLMENTERGTTVSYAKLAAMCGSPKACRAVGQAMRANPIPLLVPCHRVIASDGGLGHYMSGKGDNIKSWLLEFE
The following text describes a protein:
Function:
Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MGNSCYNIVATLLLVLNFERTRSLQDPCSNCPAGTFCDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCKDCCFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPAPAREPGHSPQIISFFLALTSTALLFLLFFLTLRFSVVKRGRKKLLYIFKQPFMRPVQTTQEEDGCSCRFPEEEEGGCEL
The following text describes a protein:
Function:
Enzyme involved in the catabolism of H(2)CO(3) but that does not mediates the reversible hydration of carbon dioxide. Mediates complex I assembly in mitochondria and respiration (By similarity).
Subcellular Localization:
Mitochondrion membrane; Peripheral membrane protein; Matrix side. Note=Probably integral to the membrane.
Sequence:
MGTLGRAFYSVGFWIRETGQALDRLGCRLQGKNYFREQLSRHRTLMNVFDKAPIVDKEAFVAPSASVIGDVHIGRGSSIWYGCVLRGDVNTVSVGSGTNIQDNSLVHVAKSNLSGKVHPTIIGDNVTIGHSAVLHGCTVEDETFIGMGATLLDGVVVEKHGMVAAGALVRQNTRIPSGEVWGGNPARFLRKLTDEEIAFISQSATNYSNLAQAHAAENAKPLNVIEFEKVLRKKHALKDEEYDSMLGIVRETPPELNLPNNILPDKETKRPSNVN
The following text describes a protein:
Function:
Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells.
Subcellular Localization:
Cytoplasm, cell cortex.
Sequence:
MAEGIAVENAQPASEVSASIRQENMIQETPTKESATSNSTAEYDNASSDSSQFVEAENEPSEPNEEQPVASEEQVEPVPKIIRRRLNGYVGFSSLPNQWHRRCVRKGFSFNVMLLGESGSGKATLVNMLLNQDLYEKCSTPYLDDDAFNEDTNQAPCVNIEKRQTEVVENGVKLRLEVLNVQGFGDYINNGDCWQPVVKEIESRFDDYLDAEKRLPRSAIEDNRIHACIFFIQPTGHCLSQLELETLKTLSDKVNLIPIICKADLMTDEEVNVTKERILREFQKEGIKIFVPPNYETDDDETKAENAEIISRIPFAVVASTDVIERPDGHKVRGRSYPWGIVEVDNEDHSDFCKLRQMLIRTHLEELKEKTHVLYENYRTELLLSRGISQDVTVFREINPNAKLEEEKALHEEKLRNMTKEMKAIFAQKVAEKEERLKQSERELYDRHHEMKMALEAQKTELMERKARLVKGTKATHDHEKPKKRFFK
The following text describes a protein:
Function:
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
Sequence:
MSNIHDMEFLQKKVQELKEQGLYKELVTLEGPSDAECVINGKKVINLSSNNYLGFANHPRLKKAAIEAIEKYGAGAGAVRPIIGNMKIHDDLEKLLAEFKREEAVLAFQSGFNCNAGVIQALTDKGDLIISDQLNHASIIDGTRLSKADKAVFQHSDMADLERVLKEKRNNYNNVLIITDGVFSMDGDIAKLPEIVALAEKYNCLTYVDDAHSSGVLGESGRGTVDHFKLHGRVDVAMGTLSKAIGVVGGYVAGKKVTIDWLKNRGRPFLFSTGLPPAAVGAAIEAVKMLMESTEYTDKLWANAKHFKEGLGKLGYNIGHSETPITPIIIGDEAKTLEFSKKLFENGLFSGPIVFPTVPKGTGRVRCMVTAGHTTEQLDRAVKICEKVGKEMGII
The following text describes a protein:
Function:
[Neurosecretory protein VGF]: Secreted polyprotein that is packaged and proteolytically processed by prohormone convertases PCSK1 and PCSK2 in a cell-type-specific manner (By similarity). VGF and peptides derived from its processing play many roles in neurogenesis and neuroplasticity associated with learning, memory, depression and chronic pain; [Neuroendocrine regulatory peptide-1]: Plays a role in the control of body fluid homeostasis by regulating vasopressin release. Suppresses presynaptic glutamatergic neurons connected to vasopressin neurons; [Neuroendocrine regulatory peptide-1]: Plays a role in the control of body fluid homeostasis by regulating vasopressin release. Activates GABAergic interneurons which are inhibitory neurons of the nervous system and thereby suppresses presynaptic glutamatergic neurons (By similarity). Also stimulates feeding behavior in an orexin-dependent manner in the hypothalamus (By similarity). Functions as a positive regulator for the activation of orexin neurons resulting in elevated gastric acid secretion and gastric emptying (By similarity); [VGF-derived peptide TLQP-21]: Secreted multifunctional peptide that interacts with different receptors and thereby plays multiple physiological roles including modulation of energy expenditure, pain, response to stress, gastric regulation as well as lipolysis. Activates the G-protein-coupled receptor C3AR1 via a folding-upon-binding mechanism leading to enhanced lipolysis in adipocytes. Interacts with gC1qR receptor in macrophages and microglia causing increased levels of intracellular calcium and hypersensitivity (By similarity); [VGF-derived peptide TLQP-62]: Plays a role in the regulation of memory formation and depression-related behaviors potentially by influencing synaptic plasticity and neurogenesis. Induces acute and transient activation of the NTRK2/TRKB receptor and subsequent CREB phosphorylation. Also induces insulin secretion in insulinoma cells by increasing intracellular calcium mobilization.
Subcellular Localization:
[Neurosecretory protein VGF]: Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus.
Sequence:
MKTFTLPASVLFCFLLLIQGLGAAPPGRPDVFPPPLSSEHNGQVAEDAVSRPKDDGVPEVRAARNPEPQDQGELFQGVDPRALASVLLQALDRPASPPSVPGGSQQGTPEEAAEALLTESVRSQTHSLPAPEIQAPAVAPPRPQTQDRDPEEDDRSEELEALASLLQELRDFSPSNAKRQQETAAAETETRTHTLTRVNLESPGPERVWRASWGEFQARVPERAPLPPPVPSQFQARMSESAPLPETHQFGEGVSSPKTHLGETLTPLSKAYQSLGGPFPKVRRLEGSFLGGSEAGERLLQQGLAQVEAGRRQAEATRQAAAQEERLADLASDLLLQYLLQGGARQRDLGGRELQETQQERENEREEEAEQERRGGGEDDVGEEDEEAAEAEAEAEEAERARQNALLFAEEEDGEAGAEDKRSQEEAPGHRRKDAEGAEEGGEEDDDDEEMDPQTIDSLIELSTKLHLPADDVVSIIEEVEEKRKRKKNAPPEPVPPPRAAPAPTHVRSPQPPPPAPARDELPDWNEVLPPWDREEDEVFPPGPYHPFPNYIRPRTLQPPASSRRRHFHHALPPARHHPDLEAQARRAQEEADAEERRLQEQEELENYIEHVLLHRP
The following text describes a protein:
Function:
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Sequence:
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKHLANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKI
The following text describes a protein:
Function:
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Sequence:
MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKNTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSTEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQEESILDGIIRELQREQDLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRRSGQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKKPSYPIQRNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQNSGVQGDSDSSSEEDETVGTSDASAEDPVVEWQSESSSSDSSSEYSDWTADAGINLQPPKRQTRQATQKIYSSSEDENVKSSEDRQKKPKQTRKKKGGLVSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAENPNSSDPEEDTEMVDLDSDGPGTSSGRRAKCRGRRQSLKCNPDAWKQQCKELLSLIYEREDSEPFRQPADPHSHPAQQQEGESSESVPPDRQDPSLSEDYQDVVDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENRIKNIISEYKSAIQSQKRRRPRYRKRLRSSSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVVYARTSSPFSSPVSDAAEGVSLYLLDDEGDGPFSPSSCSGYSRSGNSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKEKAHLSSSESGELGSSLSSESTSGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRRQHATGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRGASRGASRTKRARVADDEFDTMFAGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY
The following text describes a protein:
Function:
Possesses adenylylsulfatase activity in vitro.
Subcellular Localization:
Peroxisome.
Sequence:
MEARRLAILCSHLNPPGPNPTRDPTLRVSDCSSGSSGDGKVESSTLQNDCVFCKIIRGESPCLKLYEDDMCLCILDTNPLSHGHSLIIPKLHYPTLEETPPSVVAAMCSKVPLISNAIVKATGSDSFNLLVNNGAAAGQVIFHTHIHIIPRKERDCLWASESLRRHSLKLDKEASQLVSCVRRHLCSLPEEQLVQPS
The following text describes a protein:
Function:
Functions in the homeostasis of manganese ions.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MKFLGVILLASFLLIATFLIGLIPLYYIDKQKSSIVTNQEGADSISDFTTNADTQTINDDVSSYRVKIAVLSQFGIGMLLGTSFMLVIPEGIKACVEHDGNVGVNLLIGFLGVYVLDRLVTLWVSRKQTVYTHDAVKFQSWKDIINHPRQIWMNLIQNNVVFALFIHGLSDGIALGTTTNNDSLLIVVLIAIVIHKIPAVLSLTSLMVSRQNLMKWEVICNVFLFASSTPIGYIVLSLLNLSHSPTMDWISGNLLLMSGGSLLYASFTAFVGGDSHDHDLSVEQEVVLPHDESVYVLIGVCIPLVISYCISEE
The following text describes a protein:
Function:
This protein specifically binds sulfate and is involved in its transmembrane transport.
Subcellular Localization:
Periplasm.
Sequence:
MARSAFGWGFSVIAVLMVGSITACNTTTTTEPGQGENASQAPANLTLVSYAVTRDAFEKIIPKFTEEWKSKTGQDVTFEQSYGGSGSQTRAVVDGLEADIVALALSSDVQKIESAGLIQPGWEQEAPNGSIVTNSVIAFVTKASDNIKVEKWADLANPEVKVITANPKTSGGARWNFLGIWGSVTKTGGTEEQAFDFAGKVLANAPVLPKDARESTDVFYKQGQGNVLLNYENEVLLAKQKGENQPYIIPQDFNVSISGPVAVVDTTVDKKGTREVRDAFVQYLFTPEAQQIFAETGFRPVNEEVLAKFASQYPKVENLATIEEFGGWKKAQAEFFDEGGIFDKVITKIGRQ
The following text describes a protein:
Function:
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MAKSKNHTNHNQNKKAHRNGIKRPQKHRYDSLKYRDAKFRRNQKFANRGTVEAIRQAKASA
The following text describes a protein:
Function:
Probable Fe(2+)/2-oxoglutarate-dependent dioxygenase involved in oxidative demethylation of nucleic acids. Binds nucleic acids with a preference for ssDNA or ssRNA to other types of DNAs. May play a role in nucleic acid damage repair.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEEQDARVPALEPFRVEQAPPVIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSNLSLFGGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPRRPEDDDPTEQPRPPPRPTTSLLLEPRSLLVLRGPAYTRLLHGIAAARVDALDAASSPPNAAACPSARPGACLVRGTRVSLTIRRVPRVLRAGLLLGK
The following text describes a protein:
Function:
Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon.
Miscellaneous:
MISCELLANEOUS: Under prolonged growth on cellobiose as the sole carbon source, spontaneous mutations in chbR and nagC alter the regulation of the chbBCARFG operon, allowing the uptake and metabolism of cellobiose. The mutated regulator makes stronger contact with the target DNA sequence within the chb promoter and has enhanced recognition of cellobiose 6-phosphate as an inducer.
Sequence:
MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDYYEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFEQHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRHYREEQVIDDVPQWLKSTVEKMHDKEQFSESALENMVALSAKSQEYLTRATQRYYGKTPMQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLTEFNQ
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity).
Miscellaneous:
MISCELLANEOUS: Present with 5240 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSFVSKLLYTVSALVLFHSGFSSYEFHHLLKLNSLNNAQGAISKLPKDIMYETYAGLILFVLAVFTSFEKLQYLPIESNDGKIISQGNYLKEIALNKATNVDNLIGSNPNGEIIFTPSFVDVHMKRKICREWASNTVKKEK
The following text describes a protein:
Function:
Polymerase that creates the 3' poly(A) tail of suc22 mRNA.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDNANCVGGCKFETRSFQYRRRIPYSLGADPLPPVHPLSLKNLVDIDTDLISSQLYELYDSIILNDSGLERRYAFVQKLEQILKKEFPYKNIKTSLFGSTQSLLASNASDIDLCIITDPPQCAPTTCEVSAAFARNGLKKVVCISTAKVPIVKVWDSELQLSCDCNINKTISTLNTRLMRSYVLCDPRVRPLIVMIKYWAKRRCLNDAAEGGTLTSYTISCMVINFLQKRDPPILPSLQMLPHLQDSSTMTDGLDVSFFDDPDLVHGFGDKNEESLGILFVEFFRFFGYLFDYEHFVLSIRHGTFLSKRAKGWQFQLNNFLCVEEPFHTSRNLANTADEITMKGIQLEFRRVFRLLAYNCNVDDACSQFTFPSLTDTSFMDDYVNELQLEIVPGFSHGRDSSDTSCTESPPEPSHFAWAFDPYNATASPYYNQNINSSIDYSSIYSNDVPAIPPNVPYTFVDPYTYACYINNNSYLPPSYMDFYTWYNSPYPKSSHHFDERHGGDRHEKNLSNSRRYSRNKFHKKKQSSGPFQYYPDAFSFTPTDNNSPPSNSSSSEVVSPVSLHSEPVLSTVQAFKS
The following text describes a protein:
Function:
Acetylates the N-terminal alanine of ribosomal protein bS18.
Subcellular Localization:
Cytoplasm.
Sequence:
MKQISILTPADLATAYQIEQASHAFPWTEKTFASNQGDRYLNFKLSIGQEMAGFAITQIVLDEATLFNIAIDPQYQRQGYGRLLLEHLIEQLEARNIVTLWLEVRASNARAIALYESLGFNEVSVRRNYYPSANGREDAIMMALPMA
The following text describes a protein:
Function:
DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing. Also binds its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay. Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair. In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis.
Subcellular Localization:
Nucleus.
Sequence:
MASNEYTQPATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYGQSADTSGYGQSSYGSSYGQTQNTGYGTQSAPQGYGSTSGYGSSQSSQPSYGQQSSYPGYSQQPAPSSTSGSYGSSSQSSSYGQPQSGGYGQQSGYGGQQQSSYGQQQSSYNPPQGYGQQNQYNSSSGGGGGGGGGSYGQDQSSMSGGSGGGYGNQDQSGGGSSSSYGGGQQDRGGRGRGGGGGSSSGGGGYNRNSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSAEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGFGGGGSGGGSRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNFGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY