lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Maintains the normal guidance and termination of axonal branches of VC motorneurons. By associating with cell adhesion protein casy-1, mediates axonal interactions to establish synaptic connections between the male-specific sensory neuron HOA and the AVG interneuron. Plays a role in regulating male mating behavior.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell projection, axon.
Sequence:
MSSERRKDNPLRFALILHLLAVLVQGDIQPRFSCYNHYLAGIRTSSVLPISGHSSAPSNVKCIFENDVAFTEIHSALENSYQVMGKKSVNFQVLDLFHLRELVRRSHCTQTLTVTWKNVPEAGKGGLKVVSLLNETTRIEYSGDERQDFLFDETFAGVRHLIPDEDDNESNPTVTTTRLLCKHIPQPECLVRGKFEVDLEANLEWSYAFSFKTDITNQTLFTLRCGDTTSEVRLENDFFIRADGNAPVAVTHLSDATWHTAIVKHNQPDSHFLKIDDFPEIELGKSISDDTDKTITLSISVNGNIQLIDPTDTNDDCMYSFDKPQKRLQETVSTRTMCVGCGCPKLSGTFDGLSKCDEEDENSYNLRRDVDRLSFIHIDNAFDIDSNGAAIPAISTSFKSDSDVGLIFFGYWQNFHGKGRLQVYYHYDTISAVFCKHTDDEECSSCSIRSSEGFGKDQWIQTILWGGGDEIHLAVDSSVCRLQQLSNISLAEVYAIPQISGGAGLFIGGTWHEKKRRGLYKADAEQKYFENTREKAPVLRGCIKDVFVRGSKTDVSEMFEVQKQAMLNEPDDSNAFAVRKYCQSCIPACSEGTRCRSRAPLQDSAMICDCADELQFNTSEGTCNRERDTPVALSTAFLSENQIVLDIQNTKAILSKVWLKFALPKQINQAQRIVEFNSHRETLFNINLETDGTVNVQLHGQDTASRQLNLLDDRVHLLQLQRRTPMGTRHSAKKYDLYIDGFHTVVSDIGKLVLNNVSVTAAETEDEWSSVIVHDLGLSYEYDEHFAISHPSNVIHQVDLHSQLLPYQIRAPDLSKTGILDDSLWEKPAYVTDSEAAPVLESSPHGEVVDFTADIIEPEQLLSGRWILYSLFLTILLCLFILMCIVCYWCVLRPRAMRRTDTGSQRTIIRDSPDYAPVKMRRDSIGGISIDDDGSIGTDDTDLQAYRDIPSHRVKIYRESMVSILVPSIDQPAEAAIVKRSHSTISDQTPSRPHDTSHAPLVAVNDD
The following text describes a protein:
Function:
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
Subcellular Localization:
Nucleus, nucleoplasm.
Sequence:
MSQSQKRGAADDIDELRLEDKIRHHLTSSGKREDLKELLAARLAACGWRDDIKQRCREYVARKGREAVTTEDIVRAVRPEGRARVPDSVKAELLAEIKKFILSI
The following text describes a protein:
Function:
Member of the two-component regulatory system BtsS/BtsR, which is part of a nutrient-sensing regulatory network composed of BtsS/BtsR, the low-affinity pyruvate signaling system YpdA/YpdB and their respective target proteins, BtsT and YhjX. Responds to depletion of nutrients, specifically serine, and the concomitant presence of extracellular pyruvate. BtsR regulates expression of btsT by binding to its promoter region. Activation of the BtsS/BtsR signaling cascade also suppresses YpdA/YpdB-mediated yhjX induction.
Sequence:
MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVHKLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKPIDEARLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRMSGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILRNGLTVPVSRRYLKSLKEAIGL
The following text describes a protein:
Function:
Causes breakdown of chromosomal DNA as well as complete inhibition of lipid synthesis in sensitive cells.
Miscellaneous:
MISCELLANEOUS: Pyocins contain N-terminal receptor-binding domain, translocation domain and C-terminal DNase domain.
Sequence:
MAVNDYEPGSMVITHVQGGGRDIIQYIPARSSYGTPPFVPPGPSPYVGTGMQEYRKLRSTLDKSHSELKKNLKNETLKEVDELKSEAGLPGKAVSANDIRDEKSIVDALMDAKAKSLKAIEDRPANLYTASDFPQKSESMYQSQLLASRKFYGEFLDRHMSELAKAYSADIYKAQIAILKQTSQELENKARSLEAEAQRAAAEVEADYKARKANVEKKVQSELDQAGNALPQLTNPTPEQWLERATQLVTQAIANKKKLQTANNALIAKAPNALEKQKATYNADLLVDEIASLQARLDKLNAETARRKEIARQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVGFASLTYSSRTAEQWQDQTPDSVRYALGMDAAKLGLPPSVNLNAVAKASGTVDLPMRLTNEARGNTTTLSVVSTDGVSVPKAVPVRMAAYNATTGLYEVTVPSTTAEAPPLILTWTPASPPGNQNPSSTTPVVPKPVPVYEGATLTPVKATPETYPGVITLPEDLIIGFPADSGIKPIYVMFRDPRDVPGAATGKGQPVSGNWLGAASQGEGAPIPSQIADKLRGKTFKNWRDFREQFWIAVANDPELSKQFNPGSLAVMRDGGAPYVRESEQAGGRIKIEIHHKVRIADGGGVYNMGNLVAVTPKRHIEIHKGGK
The following text describes a protein:
Function:
Terminal uridylyltransferase which, as part of the mitochondrial RNA editing core complex (RECC), is involved in the post-transcriptional editing of mitochondrial RNA, a process involving the addition and deletion of uridine (U) nucleotides in the pre-mRNA. Specifically, catalyzes the addition of one U to single-stranded RNA with a preference for a 3'-terminal A or G and adds the number of Us specified by a guide RNA (gRNA) to precleaved double-stranded RNA editing substrates. Essential for the survival of the bloodstream form.
Subcellular Localization:
Mitochondrion.
Sequence:
MLMHTAPWLHMRLSRLFRQSPLSLPSTKLNPSPDHYAVWGKAIMAENNRRVGPEHMFRTAIRAQQQLQGLADKWTPDAKVYCCGSMVTYGQMEWGSDLDLACMFDDPYPSHEVQAKRTDKLWTVIKRYVPHYLRNNLLGLTEARTPVVKLRFANDEKVARARYTPLSEEEDRKARTALLDVRNQCVGDNDVEYIAEKMGRDNVEGIWVDRTTYGCRIAIQCTSKEQMIEAIGFFPDGKIMTRGMREDYTRDVLDVRFVPEMFMYRWDISFVGYGVKNSYLIRHYLHNGPVAARHTAMAVKAWGKATNVGAGSGAMLTSYAVTVMFIYYLLVTRQVLWVDPWSLPHPAHLPRYPDFSPLYDCDPTELGRLLHGFFIFYAHHFDYEREVVSLNRNRRSYRSDIGWNFPQNKKGTFSYNFCIEDPYEDVGTGGLNLVRHLHPAKFQLVKQEFLRAAQCMERFLPTNAPEKSILGVKRADLRHFERDRDRE
The following text describes a protein:
Function:
Participates in DNA repair and in chromosomal DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MPPTDQTRAIIHRIFSKEHSLILRGDGLRWIQDMLSHYRVAPADLEDTLNVLANECESYVSARDISTVIDQNLLQKVYEKISSMTAAQPQEAVEDADQSESSHILELQTLKVIDAFSIPRLRWSEERKMFEEPTGEGSKPSLLGQPISKISYLRDRYHTIRQVIFRNEHFSPPAVAGALGEAEREEYMKLTSSNNLLGRAGQRFLLFGRISRMKDQSYCLEDLEGWVKLDLSIASAAEGLFTEGCLVLAEGEYQSNETFKVLEIGHPPSEQRGATRKLFANIDFSGAGPLSLAEEARLKKREQNSDSQFIVMSDFHLDNPNVLGNFEQILQGYQDVLIESNNVVRPPALWILCGNFFQSHHIDGTISASTNFSKFSLVTEHIHLIFVPGPNDPWDSTMLPRQALPASIVKPLLHSTSQIPSGHLHFGSNPCRIRWMSQEIVIFRENLASKMCRNVIEALKDPTIAADEEDIDITKFLVQTILDQAHLSPFPITVSPVLWEHDQALRLYPMPTALVLADSYPAYTLTYEGCHVFNPGSFGIGSRPVWANYHVATRTSEQRQA
The following text describes a protein:
Function:
Transcriptional repressor of photolyase PHR1. Recognizes and binds the sequence AG(4) in the upstream repressing sequence of PHR1. Derepresses PHR1 transcription when phosphorylated.
Miscellaneous:
MISCELLANEOUS: Present with 2229 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MTKLIAPSEIVGGVPVFKPTYEQFEDFYAYCKAINKYGMKSGVVKVIPPKEWKDKLDLPYSAETLQKIKIKSPIQQHISGNKGLFMVQNVEKNKTYNIIQWKDLSKDYVPPEDPKARRNSRKGSVSKSTKLKLKNFESSFNIDDFEQFRTEYTIDLSDFQNTERLKFLEEYYWKTLNFTTPMYGADTPGSIFPEGLNVWNVAKLPNILDHMETKVPGVNDSYLYAGLWKASFSWHLEDQDLYSINYIHFGAPKQWYSIPQEDRFKFYKFMQEQFPEEAKNCPEFLRHKMFLASPKLLQENGIRCNEIVHHEGEFMITYPYGYHAGFNYGYNLAESVNFALEEWLPIGKKAGKCHCISDSVEIDVKKLAKSWRDNNKESKGTPPLNQLPNPAMPLLHRPTLKEMESSSLRSTSPDVGHFSNFKSKSSGVSSPLLSRMKDYSNIVEPTLEDPTLKLKRISSFQEQPLNKLLKRETSQTAMLTDHEDNIVAMSLTSMANSAASSPRLPLSRLNSSNELSNAQPLLDMTNNTLAFPRPNGPSGLNPLLYISNKNISGISHSAPHSPVNPNISLIKRVKSPNIVTLNISRESSRSPIALNYEARQQHSQQHSFSTPSTVSNLSTSVLGPLSDTNDIKTPHPERPNHKTANRILKKESPVETSKSNLILSKVASTRQEDSFTSRNDDLDKEQGSSPLNSKFAPEEIVLSGKNKIYICKECQRKFSSGHHLTRHKKSVHSGEKPHSCPKCGKRFKRRDHVLQHLNKKIPCISNETTVDAPIMNPTVQPQDGKAAINQQSTPLN
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE).
Subcellular Localization:
Nucleus.
Sequence:
MASSSSCPLAPGTSGCKPRTTRTSGVGFGVEAMARSVAAVKLEPKPEPWAAEAEEGSSVVPRSMEGPPFPAPFVAKTYEMVSDAATDAVVSWAPCGAGNTFVVWDPQALATGILPRFFKHANFASFVRQLNVYVRTGFRKVNPDRWEFANESFLAGQKHLLKSIRRRRASKPQVEASPRNSASACSGQPNKDPGVVESLKRDRAALRAEVITLRQQYSICKSQLVALEERILNNERDQQKAIAFFAKVLSNPAFVQQVLRNYARERELHGASKRQRLMENEGHRQGDLPLRGSTEAAFATGAAGVSVGTGSTNVGTAARQEESGSELNDQEVNSIWSDVWDELDLDLDAVPGAEMDRREADKGVAGFHDVEDLSGRPCGWGDEFSYLAEPMQFVEHYD
The following text describes a protein:
Function:
Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
VFITTKNNEKYQCILPAEQIKQKPYQGEYGPGPDPADLLSTLADSAKCSYRLEAYWTYELCHGKHVRQFHDERSQKIPTRKVEGRDMRYYEVVMGNGTPCDLKGHTPREVHILYLCHPQSHNEIMSVKEISTCVYEIEVLTPVLCSNELYKFQEDPVHRINCHSLPGSPDEPLSYTELVEEQRIEQSGQKEVNTDPPEDRPKAHKDFSPASQPPTQHDMPPAEFQTKIRTPKPDEQLTRDFLRGDYCLQGGTGWWKYELCYGKRVIQFHVDQDHGGRTDILLGTWDKQKHVEWVAKRSSKSIKLGYTVHLYTGGDMCDLTGRPRQVQVRLKCKESSHLQEVSLYLMEPNVCEYILGVESPIICPLLDKVDEHGLFPPID
The following text describes a protein:
Function:
Enhances the phosphorylation and activation of AKT1 and AKT2.
Sequence:
MAGEDVGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRARVQQVQVPLGDAARPSHLLTSQLPLMWQLYPEERYMDNNSRLWQIQHHLMFSGYAAEGSVPETSL
The following text describes a protein:
Function:
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing nonC and recruited to stalled ribosomes (By similarity).
Sequence:
MIMDYHSWVYPNIPEDANRQLLKLGDSLVVVGVLGRSRNRHANKMQAFDMKPNSSNYQPIEGQILCYFTPGTSTLFLHFETPWDEVILSKLLLEEKDPEKFDFDQFYETTRNRFIRHMTLALHVCHILVYVETAQIFDMKLVTIFQLLKQVREQQIMQFAPQLLAELPLVGRGVKCRLCTPRILFLFENYPHDEEKTKETISAYEFQTEDSIYQLLRHHNIVTNSSSSSLLALPNNKQFVFYNAYEDLHPDRLLQAIDSLNRAIQKTDLKEDEEDLEILELSPFEGFVKPFGEFPVSRAILLNPKDEEEQYKKDHTAWHFLQRHVQDALQNCFDEGSFKQGSPQGQQFQRLNINDWHKWMDNLYKILIANVANSNYETNNEDYRVYLRNFDQSLNYERKFWLHLCELGLKKGISCYKHSVPAFYGQETHDKLLAEAILAFEEEGRGPPSEATRAKLSAICLKYWQDGRQQCEQLSLRRHPCTQAKEAPHEKHASGIIHVSSCNCGRTQGRREDPFTLRQANYEFYEYMAQICNLCVKVKQYQFPIFEPSVSDYRAAAFEAAFPLLHGGKPNAEGGEQAAGACEEDEQLTNGCSQPLSATFGSDLNMSIGDFDSLLEGSQVEEPEISYGSADEDDEESLSNTNESLSENTENELVLQFKGPQKAANNDDELDETETIVQSSGGYSNSTTEYLPGLVHTFSNPSLLPMFPSWSLACVGPSSIYSHNTGLQEHFQSGFLSGANFLLPWDVHVRLVQAQKNQHHLQQMGKKHLQRYRKSHLSGGDRLTLKIFVGFEYECSRGHRFMMCSPERVLRGGADIERDTSHKVVHQNMPLYYPCPCRSQSNYLAQLMRIHVVTPKAPVNIILDPRVCVGQYTFTLGTVSPPRLSQSAYWMLRLPYVYQGDDNLLTPPQKLEADDILSGGYLLAGMFGVAETEANATSAPTLDTPATANFMRI
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Sequence:
MIVGIDEAGRGPVCGPLVYGIAWMPAEVYQTGILEKLGVTDSKALSANTREHIYNRLQDLPKEDFGCNTAIVSADQISRAMLAPHKTSLNLLSFEAARSLLYQLFISHEIEHVYIDLVGPESQYAAYIRELMPSIALTICAKADAKYPITGAASIVAKVIRDRNIKPQWGSGYPSDPKTKKYLDKTCHGIYGFPTHIRHSWETIKRIYDTASKCVKCVFIADTPLENGADMPTLESLGIATDA
The following text describes a protein:
Function:
Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MARSDGRSSGFAPVSARRTLRLTCPASPLHSSPAPPAPPPSLFTEVRLSVRCIELPLRRGRHLPDSVPPFRYRCACAAGAEMAAPPRKVFVWEDGTPMRFYIRPGMAKLRLAPLLLAGGAGLCRVQEPGAVHLVQPGEPAPDGAVSTDYVVACVESQRRLPLDLYRHSGPAPLAASPRGRLPFTEAEDAALLRAVRERSGARVSGTALWKELECTGLTRHSWQAMRDRYLRHLRPLHWESQQTEEAAAPMGIFEAANREFESSESGSDTSDTPDELPLQNGEGTFPLEAASGLQTGLDDCALPAAQGENKQTNTFSDSSKAEEAAQIIQHFMEEFHTDLLTVTQALLKNSGEVEATSYYLHAGQRLDGYPVWSREDDLELQKDDEDVRSKLIAKFGAENVARRVAFRKS
The following text describes a protein:
Function:
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.
Subcellular Localization:
Nucleus.
Sequence:
MEVVVAEALKPSLRTESIFQQTICEEILCLNANNVVVGEDFSVDDLLDFSNGEFQHGSVGKEVDVCEEEEEEEHEKNSTTSGSEHERTEDDDNSNSTTFSGAGDGESNSIFAGGLAVPADDVADLEWVSHFVDDSIPELSLLYPVQARSEPEPRPGPTNAYSQLSIIRRKPRTTKTRRPNCNVWIFNPILYSAKKQRKKPEAQTGGAHFQRRCSHCHVQKTPQWRAGPLGPKTLCNACGVRFKSGRLFPEYRPACSPTFSGEIHSNSHRKVLEMRRRKEVDEPVSGLNRIQMVTSW
The following text describes a protein:
Function:
Copper transporter involved in copper acquisition and transport in leaves. Required for copper homeostasis and normal plant growth and development.
Miscellaneous:
MISCELLANEOUS: The increased root length and pollen development defects phenotypes of the mutants are completely and specifically reversed by copper addition.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDHDHMHGMPRPSSSSSSSPSSMMNNGSMNEGGGHHHMKMMMHMTFFWGKNTEVLFSGWPGTSSGMYALCLIFVFFLAVLTEWLAHSSLLRGSTGDSANRAAGLIQTAVYTLRIGLAYLVMLAVMSFNAGVFLVALAGHAVGFMLFGSQTFRNTSDDRKTNYVPPSGCAC
The following text describes a protein:
Function:
Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1 (Probable). The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid. The capsid encapsulates the genomic ssDNA (Probable). Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (By similarity).
Subcellular Localization:
[Isoform Minor capsid protein VP1]: Virion. Host nucleus. Host cytoplasm. Note=Slightly detected in the cytoplasm, mainly seen in the nucleus; [Isoform Minor capsid protein VP2]: Virion; [Isoform Major capsid protein VP3]: Virion. Host nucleus. Host cytoplasm. Note=Slightly detected in the cytoplasm, mainly seen in the nucleus.
Domain:
The N-terminus of Isoform Minor capsid protein VP1, VP1u, contains a phospholipase A2-like region (By similarity). VP1u may play a role in the disruption of host tight junctions in the airway tract; A nuclear localization signal is present in the C-terminus and can be recognized by cellular nuclear import molecules. After assembly, it is hidden because it is on the inner capsid surface.
Sequence:
MPPIKRQPRGWVLPGYRYLGPFNPLDNGEPVNNADRAAQLHDHAYSELIKSGKNPYLYFNKADEKFIDDLKDDWSIGGIIGSSFFKIKRAVAPALGNKERAQKRHFYFANSNKGAKKTKKSEPKPGTSKMSDTDIQDQQPDTVDAPQNTSGGGTGSIGGGKGSGVGISTGGWVGGSHFSDKYVVTKNTRQFITTIQNGHLYKTEAIETTNQSGKSQRCVTTPWTYFNFNQYSCHFSPQDWQRLTNEYKRFRPKAMQVKIYNLQIKQILSNGADTTYNNDLTAGVHIFCDGEHAYPNASHPWDEDVMPDLPYKTWKLFQYGYIPIENELADLDGNAAGGNATEKALLYQMPFFLLENSDHQVLRTGESTEFTFNFDCEWVNNERAYIPPGLMFNPKVPTRRVQYIRQNGSTAASTGRIQPYSKPTSWMTGPGLLSAQRVGPQSSDTAPFMVCTNPEGTHINTGAAGFGSGFDPPNGCLAPTNLEYKLQWYQTPEGTGNNGNIIANPSLSMLRDQLLYKGNQTTYNLVGDIWMFPNQVWDRFPITRENPIWCKKPRADKHTIMDPFDGSIAMDHPPGTIFIKMAKIPVPTASNADSYLNIYCTGQVSCEIVWEVERYATKNWRPERRHTALGMSLGGESNYTPTYHVDPTGAYIQPTSYDQCMPVKTNINKVL
The following text describes a protein:
Function:
Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac). Drives H4 production by chromatin binding to support chromatin replication and acetylation. Since transcription of H4 genes is tightly coupled to S-phase, plays an important role in S-phase entry and progression. Promotes homologous recombination in DNA repair by facilitating histone turnover and incorporation of acetylated H3.3 at sites of double-strand breaks. In addition, acetylates other substrates such as chromatin-related proteins. Also acetylates RSAD2 which mediates the interaction of ubiquitin ligase UBE4A with RSAD2 leading to RSAD2 ubiquitination and subsequent degradation.
Subcellular Localization:
Mitochondrion. Nucleus matrix.
Sequence:
MEKKLAEYKCNTNEAIQLKLVRFPEDIEDESMTFNPEYSHQIFGDEEVAFGYKGLKILLYYSAGNLSTMFRVQYSSKVNDKFDLVQPDDVENKIHELIPAGFCSGTDDFITLLEKEVNFKPFGTIVHTYTVHNEDAGEDISYQIYKADMTSPGFREYHERLQTFMMWFIETASYIDVDDEKWDYFLVFEKYNKDGATLFATVGYMTVYNYYVYPDKTRPRVSQMLVLPPFQGEGHGAQLMETVHRYYVSAPNILDITAEDPSENFVRLRDFVLVKLCQNLPCFSPEKLLCGFSKEMVTEAQEKLKINKKHARRVYEILRLRATDMSDPEKSKAYRLDVKKRLVGPYKKNQREMAKMQQCLRPEELTNQMNQIDLNTQHEQLEESYQQLVEEYRRIVERLAQA
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSGAEPHLSLQSLTPVDLKQLSRQQKIMLLQDYRSSGARNANKMLFLATDLLAGGSSGLSSSELYDVYEQVLIASLECGRIENATMYLNLLESRFGKKSVRVSHLRGLCLEAQGKIPEAKKLYEQVLKDMPTNDFCVQRLSAIYKSNGHYKEAIRVLEEDLVYTDEDDKQHTYVEVHRGDALPTYRELSNLHYLLGNTDKAIFYAEECLLFDNESYFAHVRLGELYYMKRDLPRCVIEYSQSLLFNSQQNNSRAAYGLWQVANEMLRQHQSGVKKIEDEAVLMQTQDLRTYAAETLRRMYAGTAMLSALDAYLQREA
The following text describes a protein:
Function:
Transcriptional repressor for the ribose rbsDACBK operon.
Sequence:
MATIKDVAGAAGVSVATVSRNLNDNGYVHEETRTRVIAAMAKLNYYPNEVARSLYKRESRLIGLLLPDITNPFFPQLARGAEDELNREGYRLIFGNSDEELKKELEYLQTFKQNHVAGIIAATNYPDLEEYSGMNYPVVFLDRTLEGAPSVSSDGYTGVKLAAQAIIHGKSQRITLLRGPAHLPTAQDRFNGALEILKQAEVDFQVIETASFSIKDAQSMAKELFASYPATDGVIASNDIQAAAVLHEALRRGKNVPEDIQIIGYDDIPQSGLLFPPLSTIKQPAYDMGKEAAKLLLGIIKKQPLAETAIQMPVTYIGRKTTRKED
The following text describes a protein:
Function:
Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB). May be involved in cell wall organization and biogenesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MSTETQPAEKTKGLGFANKDGHYRRQVSQFRNAISSKPGAEFPPDKDRYHLYVSLACPWAHRVLITRKLKGLEDLITLNVVDWYMDEDGWKFNPEVPGCTPDTVNNAERIREIYFKVNPEYDGRFTVPLLFDKKQGKIVSNESAEIIRFLFTEMDSLIPEKYHVDYYPEKLRPEIDAVNEWIYNDINNGVYKSGFATTQEAYDQNVYQLFKSLDRVEKILGEHKYLVGDTLTEADIRLFTTIVRFDPVYVMHFKCNLGMIRHDYPNIHRWLRDLYWDIPAFKDTTNFEHIKKHYMISHLKQNPYQIVAAGPKENILPKDK
The following text describes a protein:
Function:
Catalyzes the irreversible reduction of the cytotoxic compound methylglyoxal (MG, 2-oxopropanal) to (S)-lactaldehyde. MG is synthesized via a bypath of glycolysis from dihydroxyacetone phosphate and is believed to play a role in cell cycle regulation and stress adaptation.
Miscellaneous:
MISCELLANEOUS: Has antigenic properties. Elicits a specific immune response in systemic candidiasis human patients undergoing malignant hematological disorders.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSSTTVFVSGASGFIAQTLVKQLIEKGYKVVGTVRSNEKGDSLKENLKAAKLQSENFTYEIVKDIAVKGAFDDALKKHPEVTVFLHTASPFHFNVTDIEKELLTPAVEGTNNALQAIKTHGPQIKRVVVTSSYAAVGRFADLADPSIPATEESWNPITWEQSLSNPLAGYVGSKKFAEKAAWDFVEKEKPNFTLSVINPVYVFGPQAFEIKNKSQLNTSSEIINGLLNSKPDSKFDNLTGYFIDVRDVAKAHIVAFEKDSIQGQRLILAESPFSTQSILDLIRKDFPQLDSQLPKGDPSQADAWKKAESKIENEKTRELLGFKFIDFKKSIDDSVAQIIG
The following text describes a protein:
Function:
Antimicrobial peptide.
Subcellular Localization:
Secreted.
Sequence:
LVPFLGKTLGGLLARF
The following text describes a protein:
Function:
Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. Plays a role in the maintenance of heterochromatin.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Forms discrete foci in S-phase but not in G2-phase. Localizes to replicating chromatin.
Sequence:
MRAEVLQIRWHYDANDDHTPIYSVDFQKNSLNKFATCGGDSKIRIWQLITSESSTKVEYLSTLSRHTQAVNVVRFNPEGNILATAGDEGTIMLWVPTNTPITTLADDAEELALAKEYWKVKIVCRSMGSEIYDLCWSVDSNFLIAGAMDNSLRLYDAHTGQLLTQKFDHSHYVQGVCWDPLNQYIVSESSDRSICLYEIQEEKKNPKKFQLVLKSRICRIEYNVTKFELISVTKPLNNDESSGISEPIETSNNNESPVSKHEALSSTANIVKDGSLERTEPPNSLNSKISYSLYCNETLVSFFRRPAFSPDGLLLVTPAGRLRPHGQPNFEVPYTAYIYTRGSITKQPVACLNGFKKPVIAVRFSPIHYELNSFSNFSFTSVSFNLPYRMVFAVACQDAVYIYDTQTCKPFYRAVNLHYSNLTDIAWNDDGNVLLMTSIDGFCSVITFEPGELGVKSQHKISLPEKRSASPSSIDDSQDNTAGGPATTTLIPRKVESSKVSKKRIAPTPVYP
The following text describes a protein:
Function:
Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). Binds to the APC activators cdc20 to prevent APC activation. Can also bind directly to the APC to inhibit substrate-binding. Required to arrest unfertilized eggs at metaphase of meiosis II, by preventing their release from metaphase of meiosis II, through inhibition of APC-dependent cyclin B destruction leading to stabilization of cyclin B-cdk1 complex activity.
Subcellular Localization:
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In interphase, localizes in a punctate manner in the nucleus and cytoplasm with some perinuclear concentration. In mitotic cells, localizes throughout the cell, particularly at the spindle. At metaphase, localized at mitotic centrosomes. Decreases centrosome localization as cells progressed through telophase.
Domain:
The C-terminal region is required for APC inhibition.
Sequence:
MMCGFTSNPSPKKLLSKSSATNVHLEISPVKPDRPCKGYENVLGSCTTVAKCADLTDDLPVHNKENLLHGFNDLERHHDEENSSLQDSGYSSILQNDSPCQDETDSNVSDIQVRDTPKNLMQYQKPFHTLSTRCLPILRFEAAMCSTLKKMRKTSKKIDWNAVDDVVCGGNYGLEHLIGKSMGLERVDILAELFHRDFKHLLTKILRHLNAMDLINVIGVSTTWRKILQKDNWAYNTYKLGCKELCEKRAKVSTHTATRDESLCRVPLASVQKVAASSLCTSKKQNKNGGLSNNRHAEFIEVAQTLKNDQSLKACVDCGSPAKYDSYLHRAICTRESCKLDFCTLCSCKYHSSKSCLISKPRSYRIPIEPLPGSKKSKQNLRRL
The following text describes a protein:
Function:
Controls stomatal patterning.
Subcellular Localization:
Secreted.
Sequence:
MSERARGLTHTRSRARCSSQPPASAMRPGSAAARVFLTAAVFLLALLGLVLEAACLPRPQSHTPRSSPLQGGAGPAREEKVRLGSSPPSCRGKCYECSPCTAVQVPTMSVGPSGPSAARREPGSAAR
The following text describes a protein:
Function:
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
Subcellular Localization:
Cytoplasm.
Sequence:
MLKQSIEIINKLGLHARASNKFTQTASQFKSEVWVTKNDSRVNGKSIMGLMMLAAAKGTVIELETDGADEAEAMRALTDLINGYFGEGE
The following text describes a protein:
Function:
Probably a biotin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTNNQKVKTLTYSAFMTAFIIILGFLPGIPIGFIPVPIILQNMGIMMAGGLLGPKYGTISVGAFLALALIGLPVLTGGNGGAASFLGPSGGYRIAWLFTPFLIGFFLKKLKITTSQNWFGELIIVLLFGVIFVDFVGAIWLSFQSNIPLLTSLISNLVFIPGDCIKAILTVVIVRRLRKQGGFELYFRK
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSSEDWDLFAVVRSCSSSVSTTNSCAGHEDDIGNCKQQQDPPPPPLFQASSSCNELQDSCKPFLPVTTTTTTTWSPPPLLPPPKASSPSPNILLKQEQVLLESQDQKPPLSVRVFPPSTSSSVFVFRGQRDQLLQQQSQPPLRSRKRKNQQKRTICHVTQENLSSDLWAWRKYGQKPIKGSPYPRNYYRCSSSKGCLARKQVERSNLDPNIFIVTYTGEHTHPRPTHRNSLAGSTRNKSQPVNPVPKPDTSPLSDTVKEEIHLSPTTPLKGNDDVQETNGDEDMVGQEVNMEEEEEEEEVEEDDEEEEDDDDVDDLLIPNLAVRDRDDLFFAGSFPSWSAGSAGDGGG