lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
A probable ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
Subcellular Localization:
Nucleus. Note=Colocalizes with PCNA within the replication foci in S-phase cells.
Sequence:
MPKIVLNGVTVDFASQPYKCQQEYMTKVLECLQKKVNGILESPSGTGKTLCLLCTTLAWREHLQDTIFACNFADRIRPLSFWGNAAADDGDPLACYTDIPKIIYAFRTHSQLTQVINEIRNTSYRPKVCVLGSREQLCIHPEVKKQESNHTKIHLCRKKVASRSLLDAKSRRAHNIDLKGTVVIFDETHKVEKMCEGLASFDLTPHDPSSGLDVIDQVLEEQIKVAQQGQPHPEFSADPTSSGLNMELEDIAKLKMILLCLEGAIHAVELPGDDSGVTKPGSYIFELFAEAQIMFQTKGCILDSLEQIIQHLAGRAGVFANTAGLQKLADIVQIVFSVDPSESGPGSLAGLGAYKVHIHPDASHQRVVQPSDAWSTTRGKVLSYWWFSPGHSMRELVCQGICFIILTSGTLAPGSSFALELQIPFPVCLENPHIIDKHQIWVGIIPRGPDGAQLSSAFDRRFSKECSSSLGKALGNIARMVPYGLLIFFPSYPIMEKSLEFWQAHYLARKMEALRPLFVEPRSKGSFSETMGVASPGSTGATFLAVCRGNTSKGLDFSDTNGCSPPRMDPLVVLKMQFLDEMKGQVGAGGQFLSGQASRAVNQAIGQVIRHCQDDRAVFLCDHRVALADARAQLPSWVRPHVRVYNFGHVVQDVAQFFHVAERTMPAPAPWAVAPSLREAEDAVRVTKSTGPLLSTRKAKSLDLHVLSLKQRPSRSPAAGDPEGSLYMEYEQEPDPAWQRPWGLLAALEHSEQWAGGPRRGAGPQVLHPELSQANFATFTQALQDHKGSDDFAALATCLGLLFADNPKKHSQLQGFYQFVQPHHKQQFEEVCIQLTGQGCGYRPEHSIPQRQRAQPALDPTGRTAPDPKLTLSKAVAQQLDPREHLNQGRPHLSPRPPPTGDPGSHPQWGSRAPRAGKQGQHAMSAYLADACRALESTGCSQLLAVLTAYKQDDDLDKVLALLAALTTAKPENFPLLQRFSMFVHPYHKQHFLPTCTDLASQPNPGMEPPGPQEESLATPPMLTHGASQPDHSWCKKPGKTQSKISSFLRQRPAGALGEDGVAGCRAKPVPWTFPRDVPNLHTASRKQSIMQVFWPEPQWVPMEALSMPSMA
The following text describes a protein:
Function:
Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. Also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation.
Subcellular Localization:
Secreted.
Sequence:
MEIKYLILFFFCGSALCCDIAPAYWCDTEAIASQCGVLPACSDRLYPSYATEADPVVVGVYFECLCPDSIRFITNMLFPTWVKLRTTGVMKIMMVPYGKATMNRHGSGYNFTCQHGPQECEGNIIENCLLNETNYDEAKYLPVIQCMERSPQPVAAAEQCITRSGLNWTNINACASSVNGTMLMHKAGLATAALNPSLTWVPWITINGIHTDHIQSSAITDLLTLVCETYKGEKPRSCQHTKHGIGAYARRQRFSNKLYFRSRG
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. Acts as an RNase, its toxic effect is neutralized by VapB1 antitoxin (By similarity).
Sequence:
MIYMLDTNIIIYLMKNRPKIIAERVSQLLPNDRLVMSFITYAELIKGAFGSQNYEQSIRAIELLTERVNVLYPNEQICLHYGKWANTLKKQGRPIGNNDLWFACHALSLNAVLITHNVKEFQRITDLQWQDWTK
The following text describes a protein:
Function:
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDANAIRSCIVATLDADADVRRRAELQLKQAEQQVGFTDVLLDLLQTEQDVNLKLSTVIYLKNRVNRAWQRSDDYPQEAVLDEDAKARFRDRLLPILASSETLVRHQLVPILQRVLHHDFPEKWPTFMDYTVQLLNTNNAPSVLAGLQCLLAICRSFRYKMSDTDHRAQFEKIVEVSFPRLLAVCDELVNQDSEEAGEMLHIALKAYKHTAWLELPACLREQSVNLGWCTIFLRTVSKPIPVSAMQDDPLGRERHHWWKAKKWAYFNLNRLYIRYGNPHNIMEKGADGQLLQFAKNFIAQVAPEILKHYLAEIEKWVAKTVWLSRPCLSYTLVFLDECIRPKEMWTHLKPHLTNLVTHFIFPVLCLSEEDVENFEEEPEEYLHRKLNFFEEVSAPDVAAVNFLVSLTKARRKQTFEILKFVNEVVNQYEQAPEDQKNHLAKEGALRMIGTLAPVILGKKSPIADQVEYFLVRYVFPDFTNPQGFLRARACDTIEKFEQLDFKDQQNLLTVYRHILDCMADPKLPVRVTAALALQPMIRHEIIRTSMQQNIPTVMQQLLKLANEADIDALANVMEDFVEVFATELTPFAVALSEQLRDTYLRIVRELLENNERRDGAEDEFGDYLDDKSITALGVLQTIGTLILTLESTPEVLLHIESVLMPVIQITLENKLYDLYNEVFEIIDSCTFAAKQISPNMWQAFELIHTTFKSGAELYLEDMLPALDNFVQYGAPQLVQKPEYIQALFEMVQDMFNDTKVGGCDRICACKLSEAMMLSLRGHIDQCVQGFIGLAMNVLTSQDVKVKSYKIHLMEMVINAVYYNPLLTLQILESQGWTNKFFSLWFSSMDSFSRVHDKKLCIVAIVALISIPADQIPPTVAVGWPRLLQGITSLFGSLPTALKNREEALKDDYHLDGGVYDENEEWDDDENNWDAGEEGEEEDLGDVKGESEAYLEFLNEEAQKFSGTDLEYSDDELGEDGVLLESPLDKLDPYSIFKTSLLKLQAEQPQYYAGLVQHLSMEEQSVISAVLQQADTQEAAAQQAAAAANGTS
The following text describes a protein:
Function:
Involved in endocytosis.
Sequence:
MTSKKSTGKLEIDVQKLRDEGNWKKLIELTEGGKIGINDQLGNFLLGEAKLEQYLEEHMPYDASSDAIAASKTGLSEAKQFLTLSAGIEGSRTTGSMDAQLLLAKLHFACGEYNEALQFLSEAGLDQLTEKPLPVRSLKIIAESFAVQALALEKIPVGTSFGKTPESKEQQLLKSMETAGDIGLLYLQEQDKLQGMLLETALLRAPLIHIKAQKWSEAIARYRTVLRAMESSATQTLRLTFARQLAEVLLRKMCQGNYWAVSSAKGPSSHWKSKYYTGSSLFSPRDVNEEVFLLLLLSEAMAVRDAVLNQSPEFRDLRKASMRNATVVYDLLIVCCIQHGQTAMLCESLERALKFSFEDAHIWSQFSYSLIAAGKFNKAVLVLKEVARLCPSNPLPCLMAAKVCLEHLNLIDDGFNLATEAVRRAVKQDSNISSRACLIRGVACFIKWRQSRIQPLKQNWMTECLKSLRESADHDPHDHLVHFYLALTHSFCRQVTQALTEVRMALRLRGEHLPSLLLLSLLLSTSAASPSSQISSSSAANGDDEEESHVNQCQGALSLAEATLEEYPNNFDLLYIKTLLEERCFGGEVALGTAKHMLALWKQLYEDSSSGGPVASESNPNNVSHSYSNYDTRSLAMSAISAQHISNDANERESSIYAQSVAAARAEHALSDVTSSMCSSLPKPGPAWHVQLKIWLLTGELYVRLGKCEEALACAQEAALLSPASHHVMYLRGLIHESKNEFAEAKTYFKNATSLSPFHIPSLQHLGLCVHYLGSHRLAEKTLRETVRLDPVAENSWYNLGKVLEAMGDYDLAARSYSTALEVQKSSPVAPFSAVPLCFE
The following text describes a protein:
Function:
Component of the mobile flower-promoting signal (floral stimulus or florigen). Promotes the transition from vegetative growth to flowering. Required for 'SEPALLATA3' (SEP3) and 'FRUITFULL' (FUL) accumulation in mature rosette leaves. Seems to acts in parallel with 'LEAFY' to induce flowering by regulating 'APETALA1'. Translated in leaves and then transported to the shoot apical meristem where it activates the transcription of several floral meristem identity genes. May play a role in both the autonomous and the long-day flowering pathways.
Miscellaneous:
MISCELLANEOUS: Mutagenesis of Tyr-85 to His converts the activator of flowering 'FLOWERING LOCUS T' into a 'TERMINAL FLOWER 1'-like repressor of flowering.
Subcellular Localization:
Cytoplasm. Nucleus. Endoplasmic reticulum.
Sequence:
MSINIRDPLIVSRVVGDVLDPFNRSITLKVTYGQREVTNGLDLRPSQVQNKPRVEIGGEDLRNFYTLVMVDPDVPSPSNPHLREYLHWLVTDIPATTGTTFGNEIVCYENPSPTAGIHRVVFILFRQLGRQTVYAPGWRQNFNTREFAEIYNLGLPVAAVFYNCQRESGCGGRRL
The following text describes a protein:
Function:
Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner, in vitro; (Microbial infection) Acts as a receptor for Japanese encephalitis virus; (Microbial infection) Acts as a receptor for Ebolavirus; (Microbial infection) Acts as a receptor for SARS-CoV; (Microbial infection) Acts as a receptor for Lassa virus and Lymphocytic choriomeningitis virus glycoprotein.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MDTTRYSKWGGSSEEVPGGPWGRWVHWSRRPLFLALAVLVTTVLWAVILSILLSKASTERAALLDGHDLLRTNASKQTAALGALKEEVGDCHSCCSGTQAQLQTTRAELGEAQAKLMEQESALRELRERVTQGLAEAGRGREDVRTELFRALEAVRLQNNSCEPCPTSWLSFEGSCYFFSVPKTTWAAAQDHCADASAHLVIVGGLDEQGFLTRNTRGRGYWLGLRAVRHLGKVQGYQWVDGVSLSFSHWNQGEPNDAWGRENCVMMLHTGLWNDAPCDSEKDGWICEKRHNC
The following text describes a protein:
Function:
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
Subcellular Localization:
Cytoplasm.
Domain:
Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
Sequence:
MIEYVRGELAELSPATAVIDCNGVGYAANISLNTYSAIQGKKNCKLYIYEAIREDAYVLYGFADKQEREIFLLLISVSGIGGNTARMILSALSPAELVNVISTENANLLKTVKGIGLKTAQRVIVDLKDKIKTMGATVAGGSASAGMLLQSASVEVQEEAVAALTMLGFAAAPSQKVVLAILKEEPDAPVEKVIKLALKRL
The following text describes a protein:
Function:
Acts as a component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MTLPLGAGGDTPTAGFFQNAEELQPQNKLSTGYPLYRKLTKVLHLSLDEPETQEALSALSDIYPQNTPSARRNLKSHVEKQVSGVSKEFLAAFDALHSQLIGIESHIDSIGNRCEQMDIQLKAAYKNAASVLKHTQDMKTKSEQASYRKVVVDALLERFTLSDTEIRLLATSSETVNTAFFAALSRVQNIQTDCQTLLIGENQRLGLEIMETTNMYQESAFEKLFRWALAECRLLKSESPEITVELKKGIQTLKQRPILFESCMEEVSNIRRATNIRSFQNALSVGGPGGFPRPIEVHAHDVLRYTGDILAWVHQAAVSEREMLEGLFDLASVASRERQIPTTNASDQSALREIKGYQADDELLLRVLEKNLEGVCRPLKSRIVSVLQSGLGPITSYRIANLVQFYSHTIIKVIGSSSEISALFDELIQDAFKIFFSALMAQAADMLRFVDAPSFDLQPPQIVKDTISQLREIMLSHDESLLSSSGQEGDFRQIVNTLLEPVLKLCEIGSASLKPLESAMYMVNCLCYIQMALSSFSFAATQIKEIQDQIDSQIHVLVQEQYSVILSQSGLENLVMHMETLQPPLAHTRTVDAKAVAEAIAKLDLFLVTVTVDVAETLSRISSVQIARRVSQRGFRKFVDTYRNIVAKIMDPINKYEFPSSLIVRSVEEVETLLSLQDSSS
The following text describes a protein:
Function:
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
Subcellular Localization:
Cytoplasm.
Domain:
The PRC barrel domain binds ribosomal protein uS19.
Sequence:
MKEFLAVGEIINTHGIKGEVKVYPLTDDMKRFKKLKEVFIDGEERKILSCKLQPNNVVLKIEGIDSIEEANKYRKKLLEIKRENSVKLPKGSYFIADLIECRVIDEDGREIGQISDVIKTGSNDVYEVKGKSEVLVPAIKDIVTNIDIENKTVTIKPLEIWQCE
The following text describes a protein:
Function:
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.
Sequence:
MKYFSTGHKESYTLIARKRHVKKLRQHQSNTTWHGTTTALTGVQQPPIRQSPDRLKGTTCDLFELLEKAQSSRLDDQRCVLPAYFNQAPLVQRQHSVPGPDPRDDCRLSTNNNVKICTTPPSSPQQATQSRRLLQETLSRPPPYPMIAVPEKGYWVDGTDHEVSFDHRGVPILPHQTWRAKIETDDTGKCYRRFYVGREHTSLIGNDETLGPVLLSIKTENVANQEHTRILLRMRTGTMHEIVPSSCLGDSPSPARMAKLLNEQLNIDNFVPVLHPKASQLIANYDEHVLVTNFKFGVMYQKFGQTTEEELFCNNITSPAFDDFLALLGQRIQLKDHKGYRGGLDIQNGHTGDQAVYEVFKDREIMFHVSTLLPYTESDPQQLQRKRHIGNDIVAIVFQEENTPFSPDMIASHFLHAFIVVQVVEPNTPNTRYNVSVTARDDVPFFGPTLPTPAVFRHGPEFKEFLLTKLINAENACYKADKFAKLELRTRTSLLQTLTEDLKEKTNEFLGGSATVVPGTPKSDSGPGSRFIDTVKKAWSARVKSSQSVDNNLANANGHERLSKKSSQPTISESTPSSGRSLSKSSIVSNGKKSPNSSTASSPDLTAHAHAHPAMSEASDDSSLTSEDLEEHLAGGYIDSDTGLESMSSAETAAKACSVCQERPTSTTGPSSSEVLAQEVAKLKCDKLDLLRQNVSCQRDIKRLREKELSLQGDLEAAKKEIIRLRELLKDYSPNGDRSPV
The following text describes a protein:
Function:
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
Subcellular Localization:
Secreted. Note=Neuroendocrine and endocrine secretory granules.
Sequence:
MTSRMAILSGLLFWLLLEWNPAFAYSPRTPDRVSETDIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPFGNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPLGKTADDGCLENAPDTAEFSREFQLDQHLFDPEHDYPGLGKWNKKLLYEKMKGGQRRKRRSVNPYLQGKRLDNVVAKKSVPHFSEEEKEPE
The following text describes a protein:
Function:
Involved symbiotic signaling. Required for root infection by symbiotic rhizobia, infection thread (IT) formation, and nodule development. Required for proper induction of early nodulin gene expression. Probably not involved in nodule organogenesis. Involved in arbuscular mycorrhizal (AM) symbiosis. Required for fungal infection of the outer cortical cell layers, and for arbuscule development during the AM symbiosis. Acts downstream of CCAMK. Required for symbiosome formation (i.e. the release of the bacteria from the ITs) and subsequent symbiosome development. Required for the expression of the nodule-specific RPG gene, which controls proper IT growth and is essential for symbiosome formation. Acts upstream of ERN1, a transcriptional regulator required for nodulation.
Subcellular Localization:
Nucleus.
Sequence:
MEGRGFSGLYKNSSEELFLKTVMESPIGMPVPTMEMLGFKTVSQSFRTDSEELFKRWLTNDQEGYNSSSMGLNSRLSKRISTEIANMSNQQHIGVASEGRNNDKSCLQNNFLANDVSSDFNFPIRDPVDRELQSSNLFLAKAWFITDQRMTRSRSSELRRRYTEMQNSQAPQGLDSMFMVPEHDTNTIKEELANFNGFDYLSMCELPSQKGTFMSPSNSSSSTFNTHQLVDVDKVSSCVSMLKGTLQRKKLECQVEKEAAEDGLNEIFCIREPLFQSAFNEEESWNQQKLVNVQGDFTDQVNDPGVMQTLEGTTNFVLDGFANQTNQIQGRTASGEPSQSESSAAAPVISSGLDACEGPSNSNQTLGDSSWKQVGESTQNKVRGVREQIMDNLKDDRKRKSLERYGSVTSAVSDGKMDNTKKRRVERSRKMAEAKERNLTPTIPSDMQAILKRCENLEKEVRSLKLNLSFMNRKDSEQTKQIEDLQKQNEDLADEKERLLEEIERILSETGKI
The following text describes a protein:
Function:
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MSHLSRVFLHSRDLPRFLGHFRARRSFHACVTTNLTTLSHTALDPVSKVFPLDLPKKSFSKLPRKTFNGAATGSVRFFSSKDDSDGEKPPEEEPYNTQLPATVAVPEVWPHVPVIAISRNIVFPRFIKLIELTNPQLIELIRRKVKLNQPYCGIFLKKNEENDAEVVNNINDVYNVGVFAQIHEMQDLGDRLRLVVMAHRRIKITGQIIDNDQDGIKEEADAEKRRRKPARNNRVKKTETKTPDDKKEPPKEQFLMAEVENVMHNKFKQTEEVKALTQEVIKTIRDIISLNPLYRDSLQQMMHQGQRVVDNPVYLSDLGAALTAAEAKELQEVLEEMDIPKRLMLSLSLLKKEYELSKLQQKIGKEVEEKVKQHHRKYILQEQLKVIKKELGLEKEDKDAVGDKFRERIKDKVLPEAVNSVIEEELNKLNFLESHSSEFNVTRNYLDWLTSLPWGVYSEENLNLQRASEILDQDHYGMEDIKRRILEFIAVSQLKGSTQGKILCFHGPPGVGKTSIARSIARALNREYFRFSVGGMTDVAEIKGHRRTYVGAMPGKVIQCLKKTRTENPLILIDEVDKIGKGYTGDPSSALLELLDPEQNANFLDHYLDVPVDLSKVLFICTANVVETIPEPLRDRMEMIDMSGYVAEEKLAIATKYLLPQAMKDSGLNDQHIKIDDEALNTLIKSYCRESGVRNLQKHIEKVVRKVAYKVVKEETNFVEVSNANLAEFVGKPVFSQERMYPTTPPGVVMGLAWTAMGGSTLYIETTTRKIAAEKETDGSLELTGHLGDVMKESAKIALTVARNYLYKIDSTNKFLQSSHLHLHVPEGATPKDGPSAGCTIVTALLSLAKNEPIRQDVAMTGEISLTGKVLPVGGIKEKTIAAKRSGVKCIILPEENKKDFNDLPKFITDGLEVHFVSTYDEVYNIVFNKNL
The following text describes a protein:
Function:
Catalyzes the reversible epimerization of D-allulose 6-phosphate to D-fructose 6-phosphate. Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
Sequence:
MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTLSPFFVSQVKKLATKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEIRRHDMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKLAELKAWREREGLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQILAAKSEVQPHAKTA
The following text describes a protein:
Function:
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MAPPHKNHNFRPENVLKRAEDLIAVGQKEAALDTLYELIISKRIRYLQVQDLEPIASLLIELAVELRKGKLAKDALHQYKKNIQLSENGLESVQTIVRKFIDLAEKKLDAAQTKADIKIDEEENAAAAAAATSSAGAGGAGGDAGGAGAGGDDDLETAQTPESILLSAVSNTDSADRTERELVTPWLRFLWEAFRAVLDILRNNSKLEITYSAIVNQAFKFCLNFNRKAEFRRLCELLRTHMQSVTTQTTTKTSGHNAIDLSDAETVQRYLDQRFAQLNIAVKLELWQESFRSVDDVHSLITASKKAPKPNMMANYYENLARIFAVSDNTLYHAAAWNKFFNLYSQSPLATDEELKRYASVLVLSTLSIPQRVVQDVDEHKSKNSKLSSLLNLTHVPTREGLIKSILSRSILKYVDEPIQQLFELLEGGDFHPLSIKQEISQLFQIIESDKEFKKYIPTLTEVILIRIFQQVSQVYDAVKLDFLISLGIFPDLEYSLSELQVEDLIVNAVKDDLVSLTIDHESGVVSFKSNPFDEIDQEFANAGTTTTNTITTTTTIGTSRLQISPAELVRTQISKLAATLSESIYLIDPNYEARQQQAKQQALQRCIKDMVNEQQRIADRSKILKDRKVAAEKRKREEEERQARLRQEKLAMEQKLEQERLIAEQERKKLEKLEKERELIKENEKRKIAEEINAKGIIKIDLNNLKELDTTKLQLMQIEQLNKDKKELETKLQATAKKADHLERAYRRYELNLLEADLEIQLDLEKKDYEFLKQSKINKAKKDHDNAIELKKRLQRILPDYSKFKSEIDAKNEVKLKQLQKEAQIKFEKAKQERIESVKKHRIEELKIRKERERKAAAEEAARQAKAAEMAKLKEELRIQKEKDEALARKRAELEAAAAAAAAPSSSPPPKKTMTFAERMRLKREGKLP
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MDRGGMAAAKMPEVGLGVPGAWTQRRIAFHATSTFSSAPAMEPLNDPVSGNGSGAGPAAAAAAGSLLANKLSKQNPQRLPSSMPLQWPTAQKIGAGLSNLGNTCFLNSVLQCLTYTPPLAGYLQSGQHKLSCRVAGFCAFCALQEHVSQALTSSGRVVAPNKLAKNLRSISRSFRMCRQEDAHEYMRYLLEALHKCCIPPELASTSSSNPKPSQDKSLVYKIFGGRLRSQVKCSVCYHCSNTYDPFLDLSLDIVRADSLTKALTRFTAVDTLDGDNKYRCAHCKKKVRAQKQFTIETVPNILTIQFKRFSSTGSMGGKIDKKVDFGTTLDMKPFSSSQESTLKYRLYGVLVHSGWSTHSGHYYCFVRTSSDIWHVLDDSRVRQVSERTVLEQKAYMLFYVREVKREAIPPAQSAPKAVPAPAPVSPPVIAAPAVIVTPKETKIVSSPTSGEIVLPKTSIVVNNANGAHGSTQEVEPALKPALPTPSEVVAKLPSPEPEASSLPVLAVPEVAVAGEPCIDTAIDKTTSVEASCTTSGIEIEAGAEADWDEHYKSGMNSAVGTPQNMLKLLRAMPRTRRYFMARAMQRANRGLPIQSTSVVAVEASSSAVRKDAKRRLSVNGEVSGNKRQQKDSSEGGSSVSVITSAVPSEKADQLKPIDQTEIEVDDAPNNLREKDSLKGASVNRPSANGLSNGHADKVDDGNKPVKNPVENGNGGSFHSASSADHDAEAVNTREGHHSAAELRDERSDPPTCQPIEVENGGPREHSHGNGANMENGSKNTNGSAHLTYKDDLYGVGVPRWNEDANGEKEVDRLLRESEKAPTPKQDLWDAEYDRGRSKKVRSKMVVDSESAEPTSGRENACLKSENPFQAHAYSKLGNGTGNGNGNGKRVGNGIGNGHSSGNGSKPGKYGVVGPQSAKRRFN
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEIITWIANNFFGTPAILLGFIVLLGLLLQKKNLSQVISGTFKAIIGFLIINAGAAVITGSLGIFEPMWKEVFGLETPPLAGFLGQEAFNAKFGSAVTLAMTLGFLVNVLLARFTPFKYIYLTGHMMFWTTTIFAGITVQAVGGDIPFWGLVLFLAVIMGLYWTLQPAITQPFLRKITGNDNVALGHTSSSVAILSALLGKVFGNKKNDAEHINLPKKLEFLRDSNVITALTMGILFVVGAVILMVKKTPGAEELIAEAGNQSFIVYSIVQSFTFAAGIAIVLVGVRMFIGEIVPAFNGIATKLVPGAKPALDAPIVYPYAPNSVIIGFVGAFIGAIIWLVVLGNTVGYVFVPTMIVLFFHGAVAGVFGNSTGGVRGALIGGFLTATVVAWGQYIMVTFFINTTVPDTAMWAADSDMFILGPIVSMLAKLFF
The following text describes a protein:
Function:
Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments. Addition of RAD54 overcomes inhibition of DNA strand exchange by RAD51 bound to substrate dsDNA. Species preference in the RAD51 dissociation and DNA strand exchange assays underlines the importance of specific RAD54-RAD51 interactions. RAD51 is unable to release dsDNA upon ATP hydrolysis, leaving it stuck on the heteroduplex DNA product after DNA strand exchange (By similarity). Involved in DNA repair and mitotic recombination. Functions in the homologous recombinational DNA repair (RAD52) pathway. Required for synthesis-dependent strand annealing (SDSA) during double-strand break repair; Facilitates geminiviral replication (e.g. geminivirus mungbean yellow mosaic virus (MYMV) and tomato leaf curl virus (ToLCV)).
Subcellular Localization:
Nucleus.
Sequence:
MEEEDEEILSSSDCDDSSDSYKDDSQDSEGENDNPECEDLAVVSLSSDADRKSKNVKDLLRGNLVVQRQPLLPRVLSVSDGAAVCRKPFKPPCSHGYDSTGQLSRRLSARKRFVPWGSSTPVVVALPTKLEASTNIERDEEEEVVCLPPDIEPLVLWQSEEDGMSNVTTIMVHSVLVKFLRPHQREGVQFMFDCVSGLHGSANINGCILADDMGLGKTLQSITLLYTLLCQGFDGTPMVKKAIIVTPTSLVSNWEAEIKKWVGDRIQLIALCESTRDDVLSGIDSFTRPRSALQVLIISYETFRMHSSKFCQSESCDLLICDEAHRLKNDQTLTNRALASLTCKRRVLLSGTPMQNDLEEFFAMVNFTNPGSLGDAAHFRHYYEAPIICGREPTATEEEKNLAADRSAELSSKVNQFILRRTNALLSNHLPPKIIEVVCCKMTTLQSTLYNHFISSKNLKRALADNAKQTKVLAYITALKKLCNHPKLIYDTIKSGNPGTVGFENCLEFFPAEMFSGRSGAWTGGDGAWVELSGKMHVLSRLLANLRRKTDDRIVLVSNYTQTLDLFAQLCRERRYPFLRLDGSTTISKRQKLVNRLNDPTKDEFAFLLSSKAGGCGLNLIGANRLVLFDPDWNPANDKQAAARVWRDGQKKRVYVYRFLSTGTIEEKVYQRQMSKEGLQKVIQHEQTDNSTRQGNLLSTEDLRDLFSFHGDVRSEIHEKMSCSRCQNDASGTENIEEGNENNVDDNACQIDQEDIGGFAKDAGCFNLLKNSERQVGTPLEEDLGSWGHHFTSKSVPDAILQASAGDEVTFVFTNQVDGKLVPIESNVSPKTVESEEHNRNQPVNKRAFNKPQQRPREPLQPLSLNETTKRVKLSTYKRLHGNSNIDDAQIKMSLQRPNLVSVNHDDDFV
The following text describes a protein:
Function:
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function (By similarity).
Subcellular Localization:
Cytoplasm, cytosol. Secreted. Nucleus. Cytoplasmic granule. Cell membrane. Note=Sumoylated form is predominant in the nucleus. Stored in alpha granules in platelets.
Sequence:
MLLLGLLLLTSALAGQRTGTRAESNLSSKLQLSSDKEQNGVQDPRHERVVTISGNGSIHSPKFPHTYPRNTVLVWRLVAVDENVRIQLTFDERFGLEDPEDDLCKYDFVEVEEPSDGSVLGRWCGSGTVPGKQTSKGNHIRIRFVSDEYFPSEPGFCIHYSIIMPQVTETTSPSVLPPSALSLDLLNNAVTAFSTVEELIRFLEPDRWQIDLDSLYKPTWPLLGKAFLYGKKSKAVNLNLLKEEVKLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPRKVTKKYHEVLQLRPKIGVKGLHKSLTDVALEHHEECDCVCRGNTEG
The following text describes a protein:
Function:
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane.
Sequence:
MPERDLVEWLALAVAVTGVPTVIALLSGARAAYGRYVDDNKGLYGFNMNGKLAWIIQESPCLFMGFLNLWNCHANVITNKPNALLFAFFIFHYVHRTLVFPLFLKGKDTPVLIMLMAFFFCTINGYIQTAWLTRVQAYDDAYATSPRFIIGMVLAGLGLFVNLHSDYTLIYLRKPGEKDYKIPRGGMFEFVSGANFFGEMLEWAGFAIAGNALVPLSFALFTACNIGPRALQHHQWYLEKFKEEYPKQRKALIPFLL
The following text describes a protein:
Function:
Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of cycloartenol to form 24-methylene cycloartenol.
Sequence:
MNLASGVGGKIEKSQILSAVEKYEKYHVCHGGQEEERKANYTDMVNKYYDLSTSFYEFGWGQSFHFAHRWKGESLQESIKRHEHFLALQLGLKPGQKVLDVGCGIGGPLREISRFSSTSVTGLNNNEYQITRGEALNRIAGVDKTCNFVKADFMKMPFQDNSFDAVYAIEATCHAPDAYGCYKEIFRVLKPGQYFAAYEWCMTDAFDPNNEEHQRIKAEIEIGDGLPDIRLTTKCAEALKQAGFELIWEKDLAIESPVPWYFPLDTSRFSLTSFRLTAVGRFFTRSLVKGLEYVGFAPKGSLRVQEFLEKAADGLVEGGKKEIFTPMYFFLARKPESSDY