lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the modification of the lipopolysaccharide (LPS) inner core. Catalyzes the transfer of a galacturonic acid (GalA) residue to the 5-position of the outer Kdo (3-deoxy-D-manno-octulosonic acid) residue of the LPS inner core, using dodecaprenyl phosphate-GalA as the donor substrate. Acts after the other GalA transferase RgtA.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTESNRRDISWIFALLAAYFVLQVGVRLATSHSLDLDEAEQAFRSQWLAAGYGPQPPFYNWLQYTVFQFAGVSLTALSIVKNLLLFISYLLYGLTARLVLRDKALVAIATLGLLTIPQMAFEMQRDLTHTVAVFFSASIFFYGFIRSLKQPSLASYLIAGIGIGFGLLAKYNFAILPAAALIAALSDARLRPRIFDWRLGLTAAVALVITLPHLFWLKDNLDFATARTLEKMTASGDASYLTQVAMGVSSLALAIISFAALTVAVFAIVFGKSLRPALGSGSEWTRLLERMMLVFLAGILLLIVFGGAAGIKDRWLVPMLFILPLYFCLKIEAAGVETGKALRRFIPVVAVIMIGVPAALYGSVAAARFTGHYERLNRPYAGMLEILRKQAEPAAILAGDSLLAGNLRQDIPGVPILSADYPGFNPDLTSRRPLLLVWLLPKGGSEALPPDMAEWLQANLGTSAPEASVIDVPYFYGRGDDRYRFGYAWVNQPG
The following text describes a protein:
Function:
May be a cell surface adhesion protein.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MATLRLIIILTLSFTATVISVTGHNITEILNEFPSYTSFNNYLTQTKLNDEINRRETITVLVFNDTVVSEYLSGLDISVVKNALSVHVLLDYFDLPKLQTIGGGSVMTTTLFQTTGEAENGAGFVNITDLVAGKVGFGSGGSGSKLNALFSRSVKQIPYNISVIEITSPIIAPGVLNRSQPLDVNISSLLEKSGCKTFAKLISDTGVLQIYETTEPRGLTVFAPSDAAFNAASLPDFKNLSNNDLISLLLYHALPVYVPKGSLLTVKNPIGTLATNQVQKFDLTVRTNGDSVTLDSGVDNSHVESTLLDKVPLSIFKIDHVLIPAGFFPHSPESAPVKSPESSPPAPVVPITAPVSTPVQVPVHGPVAASPAPVARNSPVKSPPVSSPTTSSPVAGPAPADSPDADTGNNDNNNSSGGVKASVMFLALVTVAVSGMISSVFG
The following text describes a protein:
Function:
Transcription factor. Binds to regulatory elements and regulates transcription of target genes, including acyltransferase dgat-2. As part of a lysosome-to-nucleus retrograde lipid signaling pathway, acts as a direct nuclear receptor of oleoylethanolamide (OEA) and, acting in concert with nuclear hormone receptor nhr-49, activates the transcription of genes promoting longevity and mitochondrial beta-oxidation. Required to modulate expression of delta-9 fatty acid desaturases, thereby regulating lipid metabolism; in some contexts, acting in concert with nhr-49. Involved in modulation of lipid metabolism in response to the citrate-induced mitochondrial unfolded protein response (mtUPR), acting downstream of transcription factor dve-1 and ubiquitin-like protein 5. Plays a role in modulating mitochondrial morphology and function. Involved in positively modulating life-span in a germline-dependent manner, acting in concert with nuclear hormone receptor daf-12. Plays a role in transgenerational lipid accumulation in response to a high-fat diet.
Subcellular Localization:
Nucleus.
Sequence:
MTAEGRYLEIRKKTVKSKFRFPASSSSTRCLICSAQATGFHFEAQSCSACAAFFRRTVALTKSFKCITGRDDCNVHYSMHQICRSCRHKKCLSNGMKPGGVQPKKPNIETGRAFFTKSGLKRNKKFANVSPQTADEQKLVVEGVKVPKIEVQEPNSLEDLEQDNEFVIKTPTPRKISSSTSFSASTTTNYSTPGPSPMAPCSAGPDVLTLFIREEMKLGERRRLLFSERAVGTLLGQNKHCPYKKEDIKPLVFHDFRLTIKTHIMLVYEWLQTWPELQELDDFDRMSLLRKAVLIHFLLDPSFLSYQIGEPDKLIMQNGGFISTADHHGVGWEDETDISGENKRKYYVPIMKQITDEIMPAMEAMKITFEEFVALKALACFQGGFENVSEAKRHLITQQVNRIMTSLHTHYLENSEEKIAERFGTIVLMLSNIFTAGNDFVQNHREIDIFHIWDLDKLVLQLLNLDKIMETEARETAEKRAMRNGINVVNNNNDVLLGQAKLEK
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MEGGKPHPAATGGGASSSHHAAAAAAADVAVDEAFARDLYVSQLMELGDDDWSSFAPPMDRVGSTSSLAAGAAGSRAQPIVIDDDDDAPAAAAAARTVQLYVPPPLRSGGRRTVATRQQPAPARSATAFLPRPPGGAATADIGTSSTATLPQGLPAAMAPSTELSLRPGGLIAGGAAAPRHGGRRPAARMAARAAPGTGHARGAGNGRWARAENLMAALQANPRPNVAQFGRIWTRIAAADRQLTAAAAAADTPAAVTATTGEGSHAAPAVSAGKCGQHRTPAISAGKGGAAGGMEEEEEVHRNVANENDSVSSKRQALLADRDTPAVFAGMEDGHDNDWYDSVIRDAVIAELQEDPELHGPLPVQYLTKSPVVAQPPPRATAAAIAGEEEEEEGEFSMPNFYKKWGLRPSDLDPDEAGPSTRRPRVLPLADGDLPTFDCGICFDTLPMLDLFRGLPCDHKYCLECMTTYIDGKVREGAVPVACPDPECADGGDGGAGVLHPEGCKKAIDFAAFTDWGLRLAEGAVPHDRRAYCPNRRCGILLETSGEAEPAMAACPACQHLLCATCGGEWSTADDADHRDCSKGPEAAMVKKLADERRWKACPKCRMLVERTAGCRVMSCRCRMVFCYLCGLQIGAVLEGKEKCQCLDNLGVVLVVSHLRSSQRHRRHPVADYQAREEESCRQHLYTKVVNPHLPPIAVSATNTASCRHEGVATATAHTHPRTSTQAVSPLPSVAIAMPCEHSSTTRWSRRSSLEATGSSITSARSTTGTVFNTIGHSCRRFNRVAAITVTIMARSILQIYHLVLATSGSSWEKRPHTTNILVTARFPTDGSDGGEEVGGRKVEWHRGMGHCPSHSSVIE
The following text describes a protein:
Function:
Sodium-phosphate symporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPHPLTAKYDWILAITSMAFVFSAASNGANDVANAYATSVAARTLKMWHVGILAAITEFVGAVALGNRVTDTIKSGIITPDRFIGNPGTYMLAMGCAEVGSAAWLTTATFLGWPVSTTQSIIGALVGVGFATQADITWEWTSGSVSQTAASWGVAPGIACGFSAIIFGTLKYAVLEREDPFKWGLRLIPWYIALTGGILALFITIEAPTAPSLEEFGAGKAVGIILGCFFGCLFVGYVFFMPYFHRRLVRRDARVRFYHIPLGPLLWTENPPLYFPREGEWAITNHYEDAYGEVRAGGQQTITAAVAGSVLPPADGKEARDTDIERQPDSLASSPEIAPKKRIIEPEERFLDPVRDLSWGNPRKWLGYIKYAFLQGVTRDVITHDSQLLRDIHARARRYDDRVEHMWTYCQVVSAMMMSIAHGSNDVANAVGPWAGSYHTFNSGSVETEASTPVWFLVIAGLLLGGGFWFYGYHIMRALGNKITQMSPTRGFATELGAATTVLLASRLGLPVSTTQCLTGAAIGVALMNYDLAAVNWRQIAFIFSGWVLTLPCAGLIAGLLCVMALNAPHF
The following text describes a protein:
Function:
Could be a protease inhibitor. May play an important role in mammary gland development and tissue remodeling.
Subcellular Localization:
Secreted.
Sequence:
MRCLISLVLGLLALEVALAQNLEEQVFNSVQSMFQKASPIEGTECIICQTNEECAQNAMCCPGSCGRTRKTPVNIGVPKAGFCPWNLLQTISSTGPCPMKIECSSDRECSGNMKCCNVDCVMTCTPPVPVITLQ
The following text describes a protein:
Function:
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in cell cycle progression and meiosis (By similarity).
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MDAASVLDQYVQDLANLPSEVAHILEEVRDKDLKFYETRKRIQQRDNQIHKFIRANGSLAENPKEQAAYPKIRQDFQTAMELQDEKCTLAAQALTLVAKHVKKLNDDIDKLDAEGLLGGAPPQKPISANRSRATSSATPAPEPPSRNYTRDRANSRRGGSPAASRSSTPGTRPPKKRATDKNNEAASMSKESSVGASEQLRNMPETVAVGSLDAAIRAGPGEDDEVLYCFCQQPSFGEMVACDNDDCQYEWFHYDCVGLAEPPQGVWFCPSCSKGRKGDKKKR
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MLTRHCNRLGLQIENKFVFRSSSWNCVRRIGKIACNENKYRYEMTSTEEDIDSFFSRVFGEKNYISDKSLREQIVTHKSYKHGLKRYNEPFVSVGNAVIDVCLLNHYLESGNFSTIPSYKDLVNLRSPARLAEVAKKWNPETATQCILPLKGPNSPSSSSFEKIYSSIVSGLVAVVYFQKGGVEAMNFCKKSIISDLTKDFVRPNTVHNQ
The following text describes a protein:
Function:
Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.
Subcellular Localization:
Mitochondrion.
Sequence:
MLSRVRNNAVRRNFGLGQAPCISSIITTVTCPSTSGLSANSRVQQWHARRAYRSTQALEAKKPSAGQMMREAMGILQSVGAADQTPEAKPKRTRTRKAKTAEEDVVNQDETAEPKPTRRKKAADSAEDGEEAKVENKEPKKKRAGRPRIHIPEDGSAEALKLAAKLAKREAAAAAKKRPSLKPAKISRSDEQSMLRPCVDPMQERLYDTELWSWLDYGRTSKKGLAPAAVRKYDRTRVHVTSEKMVDDVLEYMKPTLTRHQGCDIIDLNPGAGVWSTKLNDLLKPRTHLLLEPDAGFYEPMLEPLLARDGSKLIAKDGLVWAELLSVLTPEYLPHQKEHHYSADDVPERNDTLLVTANLGSYPKRRYASFASATAMILYQFNHAIRSGALFQKYGLVRMLLWLDDEDKAAILPRMAQRRRRVAVDAELNCESITHVAGPDYSNIDPSKRLWFSRDINIDRSSALAALQRMREAGIQTPAGRETKILREVSQNSDSVVAAGETPITYDFRHQAEYEELLKDFEKGKIALASEEYKAMIRMRIQIDSANKRFSNIHNNMANFHRLVDEWRIAKAANDDKEIASIMERYKEWEKSFIALGSTACGDWFVQRDNLHLWKQKSMHWDRRAIEPLVIQSDEFFPHVPLSLLDIQPKAAHKVLRSMGPNTDRSGDMAEVLMRSIMAYTNSSMSKVLDRLAPGASEFVYPMCKSLVDPDRGGVPFPGAAEITVRGMSAWQFEDVLEQWMKWPFRPALQDLISQLSDEYVEAEGEEAKFGGVSPEF
The following text describes a protein:
Function:
Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Activates the PBS2 MAP kinase kinase by phosphorylation.
Sequence:
MASELSPRAVRFSQTDDEPIARLDKHKTVSRPNPRANDSDNSNPSTDAHDDLHVREQIDELGSLSRYVESHSGSVPSLVPGSLTSSLPLANGSSSRRGASSETYANGTPSRPQRPTAPARTPSNTYQPYNQRRPPQGQPSSYMANNPHARDGSRPRPLAGTSTFRAQEREYVRRLRQQDYNNDYFDAYGSGEQYDSDSEGETPSSEGAFDSYDDAHIMFASNEDIQITEEDLRDPESRERLEWHGMLEAVLTGDVVRQEKKRLIGSNDEAFGKSAHNVELWLGIRARLCGRHLPVQKRVVEDARAALDRSINDIINFAIAGESEAGKPPFEQVRDVVNKIERIESLYPSSRELMTALKPGVYSAYQETCDAVISWYNVNEMINTELSILKKWVGNDALDFSRTKEKSPSGNGLSDESSFLDRLMKEEGLKSLHEDKGSEPKSLKKKSRLDGISRVITKAKDTLIQNAEGFQKRHLPPYIEELLTLISFPSRLIEEIIKMRLAYAKKMKDSAQQNPMMQDQMISQFQVLLKLAIKIKREYMEIARPEPGWDLPPCIDEDFDRVILEALKYYFKLLNWKLSGNKNTFKEAELLFQEWGFGNEIGRYLAHGDVEVAEQFSSLTYKAWNRLSQTFEKEVQRRPKESVPEMTKRYKQILDSVRVRQRMLQRFSRMLNDNYENACDYTIAFEQPQMLHQLYDRLIETGHFQVYSASPEHKDILIIASPTLHNRDDEIQVLMGTFTYEAAIEDPSDPYLLIIKAEDPPQWLGPVHTLRVRNEPLDIKLGHMRLIAGGCQPRLLNARKAFVDRIDMQVDPVVEQRSNLQKVNFRLMEIRKVAFKLSNAFMDSVEAIRRQTRGLNCQELIQTCFIFATEFGQRSLLYMDNNRRTMNNLKLTKLALDWVSFICDDCISSDRKTFRWAVQALEFAMGMTRGRHILGLGEDEYARLRAKVAGCMALLISHFDIMGARSSVAAQAEKKRLEGLVNQIKRLNKGQMLDDNEAAKYYQEHRLEELAKVDNYRKEILLQQSAMGRVLEASNEVDRSLAWLSSTATNFTMRWQQGHFVGGGTFGNVYAAVNLDTGQLMAVKEIRLQDPKLIPTIAGQIRDEMRVLETVDHPNVVSYYGIEVHRDRVYMFMEFCSGGSLANLLEHGRIEDEQVIMVYALQLLEGLAYLHELKIAHRDIKPENILLDHNGIIKYVDFGAAKLIARQGRTLVQDVASTKPNKSMTGTPMYMSPEVIKGENAGHFGAVDIWSLGCVILEMATGRRPWANLDNEWAIMYNIAQGNPPQLPSQDQLSPEGIDFLRRCFMRDSTKRATAMELLQHEWIMTIRNRVVEPATPSSDAGSSTTSQGALNPGNSSRGGFPGDGMY
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MEYNRQPCPIRIVEDCGCAFMMGTIGGSLFEFLKGFRNAPTGLQRRLYGGIDLVKMRTPSIAGSFAVWGATFSTVDCALVHYRQREDAWNSILSGAATGGILAARNGIRAMANSALVGCLVLAMIEGAGAAVATINAADKGAGIVIKPQRAQWEAILETIDPKRASSTQDFALAEFERVLDKCRASREPNLLQDIPVKSHERDSKQKPFYSLLDLVKLSQMF
The following text describes a protein:
Function:
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Plays a critical role in the development of the central nervous system (CNS).
Subcellular Localization:
Nucleus.
Sequence:
MAGAGVSSPANPTCKIMTFRPTMEEFEDFNKYLVYMESQGAHRAGLAKVIPPKGWKPRRTYDDIDNLMIDAPIQQMVAGQSGLFTQYNIQKKPLSVQEFRRLANSDMYCTPRYLNYEDLERKYWKNLTFVSPIYGADVSGSLYDEDVEEWNIGHLNSILDVIEEDCGVSIQGVNTPYLYFGMWKTTFSWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLATGFFPNSFKGCEAFLRHKMTLISPSILKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVATQCTCSKDMVKISMEPFVKRFQPDRYAAWMLGKDSAVIDHTLATPGTTPELQSWLHRRRKAKSSSKGSSHSRMHSKRLRTSEEPVGLDEGLALKGSKKKGSGGPSGPKVRKSVTGAACKKKVSESNQSQNINSVQLSGACRQMCVVKVNRVESKGLGFSFKSDAQNSDSPASPINDEEKRSPTEIPGVPQSLSRSTSPIPESQISNPKVIQMQPGAKEKRSLSSVSQNCLDSVRIPPLEANNISLPCHTNISTETITDSFPLQSQINGSSSLSQSLNADSNTDIQDHNNTVKAEKIHTRVDPTCIKQHSTTEALYNLKSEPAEGGSCTSNASLAPLQHNCRAGKRSVEENLFPPVLQQAAVDMPRLTPEPEDKAGICPLPPVLTQEMPSLTPATDEGLAFPKPSASSNQVAPVLQRETLTELPVHCHAENQREGADAKLSAEAGKRANHGEAGHRGNTAHWSASGLQEKTSAGVHETLIISPVTPANHPVEMEKCPAGHGGAVHSQLAQRTASPREPHPNSEEKNQDDSKDAVQMGGSVSSDTNQKFSAPVPPLPTHNANHTLSHLSQFTTHPSSDSPSSYMEAKTFSSGIWKNFSSQEPSALIQGLNPELPSNFSHDPLTYTMWSEPLCKQVTDLEVPGQDLCRSKNQEDGGVAFTWAQLEPTSLLSIGAIEPLGLCEEDQPQRGEANRAESLSKGRELGGQREVDERMYSEMLVSLGTAAEQDTASDMEEGTSDEEEQLSSGKESSSSSSEEEEDSSECDDSGLQPGEYPALTKKTTKSWRHPLRKPTARAVPTAVKQQTTSDEEPSEASLAEEEEQELEPWAKPLVHLWQNRKPCFAAEKEYNAHAASMQPYCAVCTLFMPYYQAEDKAKDCQSASAEDSPRSVSAAESPELPPGEMRRTKPLVPEICFSFREQNSPPTPTNPLLQEDGTSPLLYCQSCCLQVHASCYGVMADGIHEQWLCDRCAQGSFTAECCLCNLRGGALKKTQNDKWAHVMCAVALPEARFTDEVQKSPIDTSRIPVQRYKLKCIYCRNRCTGKRQACIQCSCGRCPTSFHVTCAHAAGVVMEPDDWPYVVSVTCHRHQSRISSAKQRANQAPISLGQTVISKHKNLRYYSSKVTQISSQTFYEVMFDDGSFSNDTYPEDIVSRDCVNRGPPEVGEAVQVKWPDGLFYGAKYLGSNVSHMFQVEFEDGSQVLAKREDVYTLDEDLPKKVKRRLSTASSMRFQDAFFTTQGERKRQRTPNSRFQNDFVALPGLRTTAKST
The following text describes a protein:
Function:
Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MEALLQGLQRQDRMGALQDSCEAELQELMKQIDIMLDHKRSQWEAETETMKTRLELKEQELNCALDSEERLNQEVRRLRQQLIQQEEETQNKTTQYEAQLSGFKEELNRLKKSYEKVQKKHLRSEMKAKAEEERSEVSRLTRRLEEFRQRSLDWEKQRLLYQQQLSGLEAQRKTLIEQTEMYQQQSHNRKQMLEQTNLVGRSELQNLSGQLHRANDSLCAKEEELETLKIQLRCAVEGQKRAEHETELSKQAVQALKEKAELRATLQAHTEFLQGSRVQKHELLPEGYRGSEVLRENNSIRSLEERLQETGQVGGETEVEAIRSKLSVSRMNEQRLQAEVTCLEDSVESVTSQCQLLAKELKGKEEYLHGVKEDHQKCLSENKKLKGQLSQAELTHKSVLDGMRKEISQLTQELHQRDIRMASSAGIDWERKIKAERQRAEREAAEHRMSLNALENLRQENCRLSELLQTQEPDVAQALVNLEQANQRLQRELLQTQEKLELIAQRRESEIQNAVDSISQELLNKQEQELRIMQERLKVYEQEMQTFRSQQDAASSGSSLESIFSEVWKEQATGSPISAASVDSAIEPVEDLASSLPVPPTSPANAVASRFLQEEEQRSHELLQRLNAHIEELKQESQRTVEHFTQAR
The following text describes a protein:
Function:
Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA.
Sequence:
MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVRFNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISMAQVRNGSFIRQAIECAVARRAASMITESQCYQLEQNLHQQRIAIERKQLDDFFELDDNFHQLLTQIADCQLAWDTIENLKATVDRVRYMSFDHVSPPEMLLRQHLDIFSALQKRDGDAVERAMTQHLQEISESVRQIRQENSDWFSEE
The following text describes a protein:
Function:
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5.
Miscellaneous:
MISCELLANEOUS: Present with 1730 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MNNGSGRYLLTPPDDLHPYVPSSKPQEQVYPDFKPWEHTAAEDQILANFVAKGFYHTPMVNFESISARSSVHESLVTQSNILSQQFDKIIKIREDHINKIPSNSTTTLHGPGFQLPNRITLTDHRKETWLHELSSSHTSLVKIGKFIPHGLKRRQVIEQCYLKFIPLKRAIWLIKCCYFIEWKSNHKKKRSNAAGADDAISMHLLKDWTDTFVYILEKLIFDMTNHYNDSQQLRTWKRQISYFLKLLGNCYSLRLINKEIFHHWLVEFINKMENFEFLPLSLHILMIFWNDICQIDTNAPVAATITSSQKEPFFLVTKITDMLLHKYYIVSSSKSMINDENYIINDIKKNNKIKLNILKILSSLILKIFQEQSLEVFIFPTSNWEIYKPLLFEIVSNADTNQNSDMKKKLELISYRNESLKNNSSIRNVIMSASNANDFQLTIVTCKQFPKLSCIQLNCIDTQFTKLLDDNPTEFDWPTYVDQNPLTMHKIIQLILWSIHPSRQFDHYESNQLVAKLLLLRINSTDEDLHEFQIEDAIWSLVFQLAKNFSAQKRVVSYMMPSLYRLLNILITYGIIKVPTYIRKLISSGLLYLQDSNDKFVHVQLLINLKISPLMKSQYNMVLRNVMEYDVKFYEIFNFDQLVEITEQIKMRILSNDITNLQLSKTPLSIKIMVAEWYLSHLCSGILSSVNRTVLLKIFKIFCIDLEVFHHFFKWIEFIVYHQLLSDIESLEALMDILLCYQKLFSQFINDHILFTKTFIFIYKKVLKEKDVPAYNVTSFMPFWKFFMKNFPFVLKVDNDLRIELQSVYNDEKLKTEKLKNDKSEVLKVYSMINNSNQAVGQTWNFPEVFQVNIRFLLHNSEIIDTNTSKQFQKARNNVMLLIATNLKEYNKFMSIFLKRKDFTNKNLIQLISLKLLTFEVTQNVLGLEYIIRLLPINLENNDGSYGLFLKYHKEQFIKSNFEKILLTCYELEKKYHGNECEINYYEILLKILITYGSSPKLLATSTKIIMLLLNDSVENSSNILEDILYYSTCPSETDLNDIPLGSGQPDNDTVVTNDDKSDDDDHTVDEIDHVEYYVMMDFANLWVFQAFTCFCIKKIMENNEPAMAMEDLKNFIFQIIEITNSNDLCSQIFDQLKDMQTIEMITQIVEKDFCTSCLQNNNQKIDDNYIVVVIEIITSLSMRFQRETSGMIVISMENYHLLIKIIRQLSELNEGNLSKREIQIDAVLKIFSFHQDSIFQRIIADLSADKPTSPFIDSICKLFDKISFNLRLKLFLYEILSSLKSFAIYSSTIDAPAFHTSGKVELPKKLLNLPPFQVSSFVKETKLHSGDYGEEEDADQEESFSLNLGIGIVEIAHENEQKWLIYDKKDHKYVCTFSMEPYHFISNYNTKYTDDMATGSNDTTAFNDSCVNLSLFDARFERKNPH
The following text describes a protein:
Function:
Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
Sequence:
MNARHARYPFLGDARDAVEEAGVDLARVVTEDDAVVERARERVVSALTDGTIGEPAATVSTRVEVLSYPVARVLVSIVDESVLVRKYATAEADAAYDRFTADESTDTDLKSVSDTTRVSRDTLLSEFDLRAHVHATPDAHTVDVPTYLLLASSLRDDDWRLVNRALDDGRVPVTDAELDTLIREAIRERVADGLPLSVPDQIADALDEPVAAIQDALADLDLTREIDTVVPELFPPCMKHLLDQVQRGDHLPHHARFAITSFLSNVGLSTDEIVDIYEVNPGFGEEMTRYQTDHIQGDSSPTEYTAPSCATMKAYGNCVNPDDLCDAINHPLSYYEVKLDDGDDDDLADWRDREDDDSPD
The following text describes a protein:
Function:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to GNAT1. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).
Subcellular Localization:
Membrane; Peripheral membrane protein. Note=Targeted to the membrane via its interaction with RGS9BP.
Sequence:
MTIRHQGQQYRPRMAFLQKIEALVKDMQNPETGVRMQNQRVLVTSVPHAMTGGDVLQWIIQRLWISNLEAQNLGNFIVKYGYIYPLQDPKNLVLKPDSSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNIKKKGILEEYEKENYDFLNKKINYKWDFVIMQAKEQYRTGKERNKADRYALDCQEKAYWLVHRSPPGMNNVLDYGLDRVTNPNEVKKQTVTAVRKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEVPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLRHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIEPQETTKRSSTLPFMRRHLRSSPSPVILRQLEEEERAREAANTVDITQPGQHLAPSPHLAVYTGTCVPPSPSSPFSPSCRSPRKPFPSPSRFIRRPSIAICPSPIRVALEGSSGLEGKGEASWSGANPGPPVTESIETSVDRSRPHSQPRAPLKARAALSLGRFLRRGCLASPVFARLSPKCPSVSHGKVQPLGDMGQQLPRLKPKKVANFFQIKMEMPTDSGPCLMDSDDPGAGESGDQTTEKEVICPWESLAEGKAG
The following text describes a protein:
Function:
Transcription factor acting as a positive regulator of the starch synthase SS4. Controls chloroplast development and starch granule formation. Binds DNA via its zinc fingers. Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promote its expression when in complex with RGA.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAASSSSAASFFGVRQDDQSHLLPPNSSAAAPPPPPPHHQAPLPPLEAPPQKKKRNQPRTPNSDAEVIALSPKTLMATNRFICEVCNKGFQREQNLQLHRRGHNLPWKLKQKSTKEVKRKVYLCPEPSCVHHDPSRALGDLTGIKKHYYRKHGEKKWKCDKCSKRYAVQSDWKAHSKTCGTKEYRCDCGTLFSRRDSFITHRAFCDALAQESARHPTSLTSLPSHHFPYGQNTNNSNNNASSMILGLSHMGAPQNLDHQPGDVLRLGSGGGGGGAASRSSSDLIAANASGYFMQEQNPSFHDQQDHHHHHQQGFLAGNNNIKQSPMSFQQNLMQFSHDNHNSAPSNVFNLSFLSGNNGVTSATSNPNAAAAAAVSSGNLMISNHYDGENAVGGGGEGSTGLFPNNLMSSADRISSGSVPSLFSSSMQSPNSAPHMSATALLQKAAQMGSTSSNNNNGSNTNNNNNASSILRSFGSGIYGENESNLQDLMNSFSNPGATGNVNGVDSPFGSYGGVNKGLSADKQSMTRDFLGVGQIVKSMSGSGGFQQQQQQQQQQQQQQQHGNSRERVGSSSDSADRSSMNVNTGGGPASTSPPYGIHHASF
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MGRCGRSNDGVIGGVRPYVRSPVPRLRWTPELHRSFVHAVDLLGGQYKATPKLVLKIMDVKGLTISHVKSHLQMYRGSRITLLGKPEESSSPSSRRRRRQDNEEDHLHDNLSVHARNDCLLGFHSFNFREQTSATDNDDDDFLNIMNMERTKTFAGNGESIKFQSHHSLEAENTKNIWKNTWRENEHEEEEELSLSLSLNHPHNHQQRWKSNASSSLSETSEAVSSSSGPFIFRDCFASSKIDLNLNLSFSLLHS
The following text describes a protein:
Function:
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MRKRKVGVEEGNRDPERCPYHLRLLRNLYGTLLRSLQEVVQDLGDGEEMGLVRDDDSVEYLILLKRSFALLPDGALERVGRGEAMNQRWSQQQVVERSIQLHLREGASSNVLCFGYGQVQSAGSKELIPAFKGLEHHHYNVATAFISTHLWVTLLARIGEERMLYLLSNAAIFVPLPNYCLLQVAGHAFNMTASIMKQLPQSISIRTTSHGELSTVLQQKAPNIEQRNSYYRTEKDANEVPEDMTLSRKRARPSSWVRRKQWRRQSTPITSCSSTVTKLSDHRGTSGNRNLGTHFVCQRREGLAEGLDDVDPVIFSHCTVDKVELPKPVHRVGFPPRIIDRSAIFYHSSFSCHAGLPANHILNTSSTNEADISRVLGSVFPALDIAATASERGSLLTAGNVTKDNLIKNVKGLLRKMVQSAKHCNYARLLSKHCPLPSYSALSLPKVKTPRLQDKKQMKSNVKGLNLLMERYFTQEKDDDYLLINSLGSSKKNCNLTRSSRPLSNGPIGGPYLGEIMHPEYCRKPVVNEGIPHEKDKATGRIADLGKLVTLSSTHSEVVNFLWAVCRSLLPESFLGCNRFRRKLCSGIASFVSLRRHENFHIQHFLNELQSFNTAWPCFSENGRRTRKISLKDSDTHALQMKAESPGCPSYAWDLPQTMLQDWLHWLFTEMIIPLLRSHFYITEAENHRQNVLYYRKPVWAKIQMLSLNHLVVKCYRKLDPTTVAAVLQKRVLGFSHVRMLPKHNGVRPIANLSSRTRCALPLITGAPKDIESSALCGKRRRTDLIDSVDYLVKFRSATRRNILKQVSFAFKSINSRLKGVHTCLKYEQETHLEDLGASVFGYKDAYSKLLPYISHLKSLPGGLPQMYMAVCDISRAYDTIKQDKLCEVVSGFLRLPVYHIRRYATIFNFMGSTRASYKQICTTSDQQHDILKLFMELAARRSHSILQDQGMVTRLKQSQILGLIEEHVKRNIVKIGPHFYLQKTGIAQGSVLSPLLCSIFFGHLDEHVLMPLLQQPASVYRNDFRSQQEGENEVEISSARLPSDLLEVPKVIENGETILLRLIDDSLFISTSQSSVARFVQLMHDGFEEYGCYANRQKTAVSFDLLLNKNQEKIALGVYMTSDGARFMRWGGLLINCCTLEVQADYTRYIGEPIKGTITVVRKKNPGAQVPIKLCHFVRAKSHPILYDLRINSPSTVRLNAYQAFLLCAMKFHAYLCSMERTCCHHSPFLLQAIEVTSSYMHGLLRKQMQEMGASAHLGMTKDEMTWLALHAFLKVLHKKQSRYTELLFLIQERLGTPKYAPLSYCPHLASARDDNRSTMFKLIIY
The following text describes a protein:
Function:
May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Subcellular Localization:
Membrane raft. Note=In a mouse immature B-cell line WEHI-231.
Sequence:
MATDELASKLSRRLQMEGEGGGEAPEQPGLNGAAAAAAAAGAPDETAEALGSADEELSAKLLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKEYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLHVLARLSEIDVSTEGVKGAKSFFEAKVQAMNVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQSTFK
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MAEVYSALSHTQRIRDIELELNDALQDYIEEQETRLAAIKRFATEVKHSVDLSAEGSPGSYIGHPVNMYLMIKRFVNEWPQVEKVVEEQSNSEAFLLDRLASSKSKFPTSEDLTGAITAIKRLQEVYALKPVDFSEGRFGFKPKTGYLLGPKDTYKIGRESYLDGDMVGTAEWMTETLRLMDLGVSNGAQAPRRTDVLDHLAFAEFKNGDGRKALNHTLELIKIDPENTRAKNNLAFFTQEMKRDENPENTRAKNNLAFFTQEMKRDESKFTKKEEEKKNVPSYKWMKSRLSQDVFENFNWHVERDIYKRLCRGEKLPTLNRATVHNPITGHLETAHYRISKNCWLSGREHGEVIDRVERRIAAMTRLNLETAEGFQVQNYGLAGQYDPHFDFSRDLANSSLGSLGTGNRIATVLVWMSQVESGGATVFPYVGARILPQKGDAVFWHNLLRSGDGDFRTRHAGCPVLSGIKWVANKWIHEYGNEFHRPCSLRRDE
The following text describes a protein:
Function:
Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MAEAKLRNLLKIIHLRNKYDAVVVAIHACLLDREFKCVASGNQRNPSDEFDFGEMLPPDWNQSDDSYSLQYKHHNTGPLYILSILKLGNALAIYLLEEDESKMYDITVNVDDFTDDDLDYTTLQTQPSTSINQCFQQFDRLRAKLSRDVIDKFTKPRTQAHGHTNNQDTSRRQPSQGNPSRLLETDPLRLPPRRPPDFRDEWAPPVGPFPYGEGDRSPGFPGGGGMLMDPFRTGRFPRVPGGPTGPNPPGQIPRGSVPPGARFDPFGPIPPDGEVGARPGNPPGRFAGPDPDHLPPPGYDDMFM
The following text describes a protein:
Function:
Involved in protein export. Participates in an early event of protein translocation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRKTTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAPQTDATAPAESAPATEAPATETPAPVAE
The following text describes a protein:
Function:
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Sequence:
MIRKAQFKKSEIEKFRLEIARSIVAGKLQNCRSVLSRTARKSKNESEKQDIKEAIGKIEKNISLLEKAESIESIRGYEGASAKTYFSVFDYCIIQQKEDFQFHKRTRRPPRSRTNALLSFLYSLLTNDCIAVCQAVGLDPYIGFLHDERPGRPSLALDMMEEFRPFIDRLVFTLINRKQIQVSDFLEKPGSVFFINDDSRKELIKSYQERKKEEIFHPWLNIKSTVGELPYLQARIFARTLRGDLKYYIPFIWK