lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSTLSLPQTSYIHDHSRTFIDWLKSWLLTVDHKRIAILYLLAINFFFLLGGLAATVVRIELITPQGDLMSSDVYNRAFTLHGVIMVFFFLIPSIPAVLGNFLVPLMIGARDLAFPRLNLLSWYLYMIGGIFALIAAVFGGVDTGWTFYTPFSSTYSNSNVVMTITGAFIMGFSSILTGLNFIVTIHKMRAPGLTWFRLPLFIWANYATSIIQILATPVLGIALLLVIVERVWGVGIYDPALGGDPLLFQHLFWFYSHPAVYIMILPAMGVVSELISTFSRKRIFGYEFIAFSSIAIAILGFLVWGHHMFVSSQSVYAGLIFSFITMLVAIPSAIKVFNWTATLYKGSISYRTPMLYALGFIGLFVIGGLTGIFLGVVAVDLHVTDTYFVVAHFHYVMVGGTIMAYLGGIHFWWPKMTGRMYNETWGSIAALIIFVGFNMTFFPQFILGYLGMPRRYHVYPPEFQILHVMSTAGASILAIGFIVPLIYLGISLWKGRIAGDNPWGATGLEWKTSSPPPTHNFDKTPIVTEEAYAYPPEAAERDAASWRPGSPL
The following text describes a protein:
Function:
Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in different hemicellulosic homopolysaccharides (branched and debranched arabinans). It acts preferentially on arabinotriose, arabinobiose and linear alpha-(1->5)-L-arabinan, and is much less effective on branched sugar beet arabinan. When expressed in E.coli, the recombinant enyzme can hydrolyze, with relatively low catalytic efficiency, the terminal alpha-L-arabinofuranoside at the C20 position of ginsenoside Rc to produce ginsenoside Rd, a rare ginsenoside that exhibits diverse and powerful pharmacological activities.
Subcellular Localization:
Cytoplasm.
Sequence:
MKKARMIVDKEYKIGEVDKRIYGSFIEHMGRAVYEGIYEPDHPEADEDGFRKDVQSLIKELQVPIIRYPGGNFLSGYNWEDGVGPVENRPRRLDLAWQTTETNEVGTNEFLSWAKKVNTEVNMAVNLGTRGIDAARNLVEYCNHPKGSYWSDLRRSHGYEQPYGIKTWCLGNEMDGPWQIGHKTADEYGRLAAETAKVMKWVDPSIELVACGSSNSGMPTFIDWEAKVLEHTYEHVDYISLHTYYGNRDNNLPNYLARSMDLDHFIKSVAATCDYVKAKTRSKKTINLSLDEWNVWYHSNEADKKVEPWITARPILEDIYNFEDALLVGSLLITMLQHADRVKIACLAQLVNVIAPIMTEKGGEAWRQPIFYPYMHASVYGRGESLKPLISSPKYDCSDFTDVPYVDAAVVYSEEEETLTIFAVNKAEDQMETEISLRGFESYQIAEHIVLEHQDIKATNQHNRKNVVPHSNGSSSVSENGLTAHFTPLSWNVIRLKKQS
The following text describes a protein:
Function:
Transcription factor required for terminalia development. Negative regulator of the JAK/STAT pathway: represses JAK/STAT-dependent expression of ventral veins lacking (vvl) in the posterior spiracles (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MKEFQRMLMLQYSKHGECILKEIGAAFRGEHPADLTIVCENKVKLHAHKLVLAAASPLIRNLLEDTHLSDCSTTVYFPDVNATYFKFLLDFLYSGQTCITSRDVNYLHDLLLLLQIKSDSWKTTDSAYLNSKCGSIRERSRKQYSSSQNLDQTLKYEVDSVDESRNAADFSACSAEHCESAPECGGGGVAKEEDDECTHKDNRSEKDTDEIVNLSNAPPSGISNHSNTNSNSSNNNNNNSAINPVNLSLDLRTKSENSARSDASRTIGSGSDHSGIDLAISASESTKRKGLFFDSHKDVLKPLSDGSDINSSPENYVVTPHRKRRPGFHNTQSDNQPFTSYQQNLLEELRLVKSTTSPISGFSSEKNMLAHLEDGALNGDTLTPDRKLIESQRNHAQSPDIPMHLGPQFVYQWQSNQNAAISAMPNLQSRLSSLSHMNLGLDPEGRSSSASGSNIASSNPHSSSVREYRCEYCGKQFGMSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRNIITTTNGTDTENRYSCCFCSMCFESVQELVRHLSGHHNNLLLTKNLRE
The following text describes a protein:
Function:
Polynucleotide 5'-kinase involved in rRNA processing.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MLDEHILKEMKLSFQLTEQRELASGRRKPEKPQHPPAVPKKKVISKVASNPAKISETMIQKAQMESPKKSKKNKTAGAKRPLSNNVSNPDSSPSQKRLKKDNTLPKKNPVNKSSNVAAKKSAATSKSAKLPIPKVHSINELAPKKTKVKTPNKTKEASLSKKHKVNGNKSSMKVVQNGKVVEIIGTAAETSDIEMNSLDDWSEEDDYLIESDSENDVVEEIDETFLKDPKIFKVKCKGPEYKLSDILPPFEHDEYQPLLLDGDGSGTVRKIKVFKSAQEETDSDEDDIDYEPEDSDDFGSEEFDSEESDSEDTSSADYDSDGDFYSEYSDMEDVSDSDSEEFGSDIFDTDDLDSTYEPPDIEGFFDHPPVGMQREPLIIEEIFDDPPVEKKQERIEQSSVMDIVVKNLSSVPPKKESEVAIETEENDEVSLPEVVTPEKENYLQPSDVPFYRNPQANPTELSVFENSLKSNHVLAVIKEDLEVYGTLVLTLLCGQISVNGYRARRQEAITIYSPKGLNWVSISPTKTKKPVKDEVNWEELNKNFTRAQLDRIKTSFQRQTNAIVLLHRNTSAQQLVDTFGKHMAQNVFPLVNSSNRPFGQSETLLHCLIQSSDQSRTLQVPQVWNKLQMHATSRIIVAGGKGVGKSSLLRYLINRNLGQFPSMLLIDLDIGQPEIFVPQTISCTVIDEPLLGPGFLYNRQPEHAIVVGHTNIVLCAEQYARAVIQLVQNIQNDAKYSNIPWLINTMGYNKGFGIELMALLVDRIRPTDLVQIASPIPINNFDSVLDRNSLSQIKPIIYSAEEFKINEIPKYTLHKLISAVPAREKGTWSLSAKDMRYSNLLARLSSCLTGNAKSLTDCQPLGVSLESLKILHPTSKNYSREELIRGMEANVVYLCHHGAGLPQCLGIGVVRAIDYERKELYLVPAMPLQKMSLVDCLILGGEQSLPQGFLRDQGQGVSSSVPFVFILDDSKSSKSIQQIYHRAPAFLGVPANQRN
The following text describes a protein:
Function:
Plays an important role in membrane trafficking through the secretory apparatus.
Sequence:
MEVEQTSVRSDTNSTCEYLDAEGDPESPNLYQEADPDQEAEQQNHSIISELRDGLGTMRDNSALSPEPGQENKGLAASVESLALSTSTSAKTEDSIGGGLEEEYDYQHDSLWQGQKKHIFILSEAGKPIFSLHGNEDKLATLFGVIQALVSFVQMGQDAITSIHAGGIKFAFMQRSSLILVAASRSNMSVQQLQLQLGDVYNQILSILTYSHMTKIFERRKNFDLRRLLSGSERLFYNLLFYDSSSAKVSNNIFTFLTNSIRVFPLPTTIRSQITSAIQSNCSKIKNLVFAVLIANNKLIALVRMKKYSIHPADLRLIFNLVECSESFKSSENWSPICLPKFDMNGYLHAHVSYLADDCQACLLLLSVDRDAFFTLAEAKAKITEKLRKSHCLEAINEELQQPFNAKLYQQVVGIPELRHFLYKPKSTAQLLCPMLRHPYKSLTELERLEAIYCDLLHRIHNSSRPLKLIYEMKEREVVLAWATGTYELYAIFEPVVDKATVIKYVVKLIKWIEKEYDVYFIRNHATF
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MMNKRKRVEELGETKHRQVRQRILQEHKNDILENLAFELSDKVRRLRSNASLLASTIRMRGEMRIAAIPRAQRNMHLRDLKNHLSCNVSATPWRTKIKEFYNLDELSSQKSARQPTKTVASSSSSSSKSTTVSKSSSKSQV
The following text describes a protein:
Function:
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase, which is required for SPI-2 T3SS-dependent F-actin meshwork formation in infected host cells.
Subcellular Localization:
Secreted. Host cytoplasm. Note=Secreted via type III secretion system 2 (SPI-2 T3SS), and delivered into the host cytoplasm. Localizes on or close to the Salmonella-containing vacuole (SCV) membrane, and to SPI-2-induced F-actin structures.
Sequence:
MPFTFQIGNHSCQISERYLRDIIDNKREHVFSTCEKFIDFFRNIFTRRSLISDYREIYNLLCQKKEHPDIKGPFSPGPFSKRDEDCTRWRPLLGYIKLIDASRPETIDKYTVEVLAHQENMLLLQMFYDGVLVTETECSERCVDFLKETMFNYNNGEITLAALGNDNLPPSEAGSNGIYEAFEQRLIDFLTTPATASGYESGAIDQTDASQPAAIEAFINSPEFQKNIRMRDIEKNKIGSGSYGTVYRLHDDFVVKIPVNERGIKVDVNSPEHRNCHPDRVSKYLNMANDDKNFSRSAIMNINGKDVTVLVSKYIQGQEFDVEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFFVDGDQIVLSQESRQQRSVSLATRQLEEQIKAHHMIKLKRAETEGNTEDVEYYKSLITDLDALIGEEEQTPAPGRRFKLAAPEEGTLVAKVLKDELKK
The following text describes a protein:
Function:
Binds as a ligand to a family of frizzled seven-transmembrane receptors and acts through a cascade of genes on the nucleus. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May have a role in limb and CNS development; may be a downstream target of Dll that acts in the specification of these primordia.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MSCYRKRHFLLWLLRAVCMLHLTARGAYATVGLQGVPTWIYLGLKSPFIEFGNQVEQLANSSIPLNMTKDEQANMHQEGLRKLGTFIKPVDLRDSETGFVKADLTKRLVFDRPNNITSRPIHPIQEEMDQKQIILLDEDTDENGLPASLTDEDRKFIVPMALKNISPDPRWAATTPSPSALQPNAKAISTIVPSPLAQVEGDPTSNIDDLKKHILFLHNMTKTNSNFESKFVKFPSLQKDKAKTSGAGGSPPNPKRPQRPIHQYSAPIAPPTPKVPAPDGGGVGGAAYNPGEQPIGGYYQNEELANNQSLLKPTDTDSHPAAGGSSHGQKNPSEPQVILLNETLSTETSIEADRSPSINQPKAGSPARTTKRPPCLRNPESPKCIRQRRREEQQRQRERDEWFRGQSQYMQPRFEPIIQTINNTKRFAVSIEIPDSFKVSSEGSDGELLSRVERSQPSISSSSSSSSSSSRKIMPDYIKVSMENNTSVTDYFKHDVVMTSADVASDREFLIKNMEEHGGAGSANSHHNDTTPTADAYSETIDLNPNNCYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAAPEMAFIHALAAATVTSFIARACRDGQLASCSCSRGSRPKQLHDDWKWGGCGDNLEFAYKFATDFIDSREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEAENSHILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKNQRAAADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSGSCSLITCWQQLSSIREIGDYLREKYEGATKVKINKRGRLQIKDLQFKVPTAHDLIYLDESPDWCRNSYALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTKVLEEHTCK
The following text describes a protein:
Function:
Essential for mitochondrial biogenesis; Required for intron-independent turnover and processing of mitochondrial RNA. Participates in 3' mtRNA processing where it hydrolyzes single-stranded RNA or partially double-stranded RNA with 3' single-stranded tails.
Miscellaneous:
MISCELLANEOUS: Present with 1070 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MVVRRKVHVLLIARSFHSYTPCFRVTTRGKRQRSKSKQQAKVELDHTRELDNDQATETVVDRSVGPEKDIESINKDFLQRTKGLEPDIELKQLPQIKQEFNQRYKDRYVKPSEDWYVNSWRSLTKPKIPLYKLINSDFQLITKLKAPNPMEFQPVQLMESPLNVGDFVLLKMRPNELAMCVSLPSSTMDPRYTFVTIDGTMCFATKNRVLLRIPHKLPAGIHSLIQPESHHKHLPIGTVKNFSNQTNILPIVARQLITSRYPAQISKLAWKDLPITTKKLQLLHRSLQNYMGPWQIPFFTLVGLVQKLDLNKALDDKNGINYLTSLVNNYHTVNDIPINSPTFVSTYWAIMQQQESNLWGEIHLNTALLSPISVTIIPLKSQHLYYAQVIEKLEANSYREVNKFVKLVNERKYRDISALYPSVIQLLKDFAAGNFHNNGIIVALISKIFRKIERYKDCDITRDICQDLINEITPNSIPNPLLLNMDLALPASSKLVKWQQKLYDLTNIEELQWKKSGTDDDRYDFGDLRVFCIDSETAHEIDDGVSVKNYGRDGLYTLYIHIADPTSMFPESTNVDIEGISTDILNVALKRSFTTYLPDTVVPMLPQSICHLSDLGKQGQRTKTISFSVDVKITSKCSGKSIEIMYDSFKIRKGIVSNFPKATYEDVDRILGTPNSEASPVKKDLESLSMISKLLREQRIKNSNAVIFGEGFNKGLVMLNADSEGELTEVTFSDQEETLSTILVSEMMILANTLTGRYFAENKIGGVFRCYKQLPLGEVAQQQYDSMITSTKKGIFPKLKDIVKLSSLLNSSFYTGRPFRHEMIGAKQYLTVTSPLRRFPDLINHLQIHRHLQKKPLCFNQTQIDSLIWPIQSRADILKRASRNSSTYWTLNYLKKLTKLEPERTFDVMVTSVPQNGFTGCVFPDLSFARGTLKLHPSSMHYPMIGDIVKNCKISKIDCLEGMLELEKL
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MWETFRILASVGKIWEDHDIEDQYKDQERKQRNHMVERLCGSEEGSQCGENINFIPNLNLNKKTTGAKPWECSARGRVFMHHSSLKMHVRCHTEHKQHDYKKCGEKRCKCKECGKAFTFLSSLRRHEIAQTGEKPYECKKCSKAFTSSRSLQDHESTHTGEKSYECKKCSKAFACSSYLQKHERHHTGEKPYECKKCSKAFSISAYLRIHERIHTGEKTYECKKCSKAFSSSRSLQVHERAHTGQKPYEYKKCSEAFTSSTSLQRHEDITLGRNLMNVKNAVQHSLIPLLFGYMKELILERNSVSVKNAVKHSLVSVIFKNMKALILERTSTNVKNAVKHSLLPVIFKYMKEFTLERNPMNVRNVVKHSLLPLLFEDMKEITLGRNLMNLKNPVQHSPLPVLFENMEEVTLERKPVNVRKVGKPLFLMQTFEDMHECTLEEKACKCKECRRDLSSQFFLKA
The following text describes a protein:
Function:
Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity; Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with rbx-1 to recruit the Nedd8-charged E2 enzyme to the cullin component of SCF-type complexes.
Subcellular Localization:
Nucleus.
Sequence:
HKLKSVQKEKVRQFMSFTQTNERTALACLLAHDMKIEVAIDNFFQFPDRYAIREARQPTIDRKRIEQLFNRYKGLIFTQITELVNLYFVLIKILKDSFEDEKITADGMMRFLDDLGLNPESRTVLILAWKFNAATQCVFTREEFINGFIELGVDAIDKLKMRCATLEQEIIDPVRLKEFYQFAFNYAKNPGQKCLGEFKKSVIMFQHFQFLLQTDLDMAIAYWHIVLKDKFKFLDLWIRYLNVSFIILFVLLHENYKRSISKDTWNLLLDFSQIINDDMSNYDEEGAWPVLIDEFVDYAKPILDKRNTETETTL
The following text describes a protein:
Function:
In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links. Blocks inhibition of adenylate cyclase activity mediated by ADGRV1.
Subcellular Localization:
Cell projection, cilium. Cell projection, stereocilium. Nucleus.
Sequence:
MAESFDSPRRDMTNGATHAGARHLLRRQQRQHNGQARGLRSPSPMGRVILINSPVDGGDDSEDIHTITVDKSADGRLGFSVRGGSEHGLGIFVSKVEDNSSAEQAGLCVGDKIMEVNGVNLESITMSSAVKVLTGNNRLRMVVRRVGKVPGIRFSKEKTTWVDLIHRRMVVEESGRTPSEASSDGALRRIVHLYTTSDDYCLGFNIRGGKEFGLGIYVSKLDPGGLAEQNGIKMGDQILAANGVSFEDISHSSAVEVLKSHTHIMLTIKEAGRYPAYKEMVAEYSWLNKLASGPLQSSSQGSDTNSSASSFSSGTPLSSLSGLSQVMFPSSLPQFGSEMVDVCISTEDSRRPSCSERTEMAIQTDLQLPPNSTLEPEALARPGKIVTTETSRTLGATVLLRDTAIRNEGTDEVPSRDRTLSTGDLADEQLESPKTAVLLALSRPRRPIRRSQSHVTVLASLEWNSSLFSVDLISCAEPLSVSSEDKKKKKTVKLGGEGTGLQRSKTFVSLLFKSGRKRDASRDKKEGAAGEGRSRSKSPARSESDRDKERGRLFSLFSSPKESVAALREQTPLPHSEALALVEDMARKLLNEDEVTAIMRHCQRFVSDHVVEDLVRPLLAILDRPEKLLLLREIRTLIPPTDLGRFDSMVMPFELEAYDILKSRSGKKIESVISLLHGASACEHLLTGQRYYRGGFQLKPVQDFEKDRQLMAEIEKLRLSGLQDIRQLPSRTLTPLQDVQVDSYSAEALKPLPASPMRSNWLLAETQRSETDAPLRRDNPGTVRSVHYDEVSLHSTADRGHTTSERGRSPFRNGQAKARKEKAEKSKDSLYTVINAPRRSRPMLSEIFGGTGVRAGRGQVNGHSQNGLSGSPASAPVEEYELTTVTISKTKQSLGISISGGMESKVQPVVKIEKIFPGGAASSSATLKAGYELVSVDGESLQGVTHQHAVDTIRRAFSNKATDPMVFVVKVPKSSR
The following text describes a protein:
Function:
Microtubule-binding protein which plays an important role in mediating dynein-dependent transport of RAB8A-positive vesicles to the midbody during cytokinesis.
Subcellular Localization:
Midbody, Midbody ring. Midbody. Cytoplasm, cytoskeleton, spindle. Note=Associated with microtubules, in particular, with stabilized microtubules of the mitotic spindle during metaphase and with midbody microtubules during cytokinesis.
Sequence:
MAKTGAEDHREALSQSSLSLLTEAMEVLQQSSPEGTLDGNTVNPIYKYILNDLPREFMSSQAKAVIKTTDDYLQSQFGPNRLVHSAAVSEGSGLQDCSTHQTASDHSHDEISDLDSYKSNSKNNSCSISASKRNRPVSAPVGQLRVAEFSSLKFQSARNWQKLSQRHKLQPRVIKVTAYKNGSRTVFARVTVPTITLLLEECTEKLNLNMAARRVFLADGKEALEPEDIPHEADVYVSTGEPFLNPFKKIKDHLLLIKKVTWTMNGLMLPTDIKRRKTKPVLSIRMKKLTERTSVRILFFKNGMGQDGHEITVGKETMKKVLDTCTIRMNLNLPARYFYDLYGRKIEDISKVPLLEKCLQNSITPLRGLLWVSKGEGFSPSGAKMYIQGVLLALYQRLKSAKKYYKQLNLVMNEQKEKITEKVILSMTAKEHHKEQEEVSRLIDELQTAIKSNIGHLCKLGPQLQAEQEQFSSYVYQHIKSLPANTLVPGGLQLKVFENGKNTGEISVGISKKDLGSDSPIQTDHMMERLLLKIHQRLQGSSINPPGLNYSSMRLFDENGQEIKNPLSLKNEQKIWVSYGRAYRSPLNLALGLTFDRVSAFARGDIMVAYKTFLDPNAVLLPGCGNWEVCEGFPINFNCTSQQIPDQFEKVDLENHFLQNKVDPNIVLHASVSIGKWSFSGSEASSRSQIAPSILWPVASVWLITKTGMILSRAITQGCLAIGHPIRVKAAEGTSLEGYKLILQKRHSGDDSQKWVFGTDGCIYSKAYPQFVLTYLEELNAQVDVTQTEYHIHHGAWTTAHQEHGRNLAEEVLQESASNLGLKQLPEPSDTHLMPEGSLEETGELTVALVRKLEEKHPKASAQRWAIKHEGTSKPGQWKHSRVENPLWNKLTYMWPVLPSGQLNEEFDWPIQGLLVPSSPPMKKPICKTTEPYAPVRLRVLQNGEKNKNRSVTILGPDISPGRKTQCTEILNLPSAARRLYNEKGKEIFALKDLQRDELVYVSCGELWINPDLSIAQQKKQIFLRNLESDIAKIQIFCSTHKIEALVLEVQSDIVSGSKLAVHKPVAIFGEEKQVTEPEEKQMQEDPLTTENASSEILDSHVRAHLRMKACHTLPRYAWQETSHDFDEDDSLPKKTEKGLFENVEPQKKHSCSPKHSKLHKHCHQQFEYRDGQIISHAAPQLVLGVQGPNLRSGMEVVLVEKKSDGSHQRWIHQEDSRTFHLVSNPDLVLAVSMTKTRNEVCGYPVIVQKYKPYNNGAANQKWHYMKNIKALVAFHSTALDKEITSANYAGVCTSSVIKEENIDQPGYCYLSPDGKRKTMLCLACGQSMRTEKGLKQLLPGVPFLCISGTKTQKPFLQGPFKVISVAEVDLSCDKAEKTLSYYQARLLSLRMKTCTQAASHSGMAATHQKAVKIIAYKNGDGYRNGKLIVAGTFPMLLTECTEQLGLARAASKVYTKDGTPIFTLRDLVLWALDESFLQRDSEKQKQDAAPVGKEQIIVEKNPRMKVKNRLFAKSVTSDSLDGIDKSLLTLILRNPIAIWVSCGEPFLPPNALQKAEKLEKQNWLKKDRILADLDTMRHKMRQLKGRRVAACQPATMVPTKSPVQPVVVEGGWTEQTQQEIKLMELIRHTEAHLSEIQEMESKINFPIATKRIAVKPSNLYKQPNTKRVWIYLNGGRPEDGTYAWGKTISELLQDCSSRLKMTHPARALYTPSGEPIQSWDDIERDMVICVSMGHGFKTPKELKQLMEIRANYARIRRQQGPQATDIVVSPSTKLLSLAHLHN
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MEEVEAANKAAVESCHGVLNLLSQQTNDSKSIMVETREAVCKFKRVSSLLSRGLGQRKIKKLNNNNYKFSSSLLPQHMFLESPVCSNNAISGCIPILAPKPLQIVPAGPPPLMLFNQNMCLDKSFLELKPPSSRAVDPKPYQFIHTHQQGVYSRSKSGLNLKFDGSIGASCYSPSISNGSRSFVSSLSMDGSVTDYDRNSFHLIGLPQGSDHISQHSRRTSCSGSLKCGSKSKCHCSKKRKLRVKRSIKVPAISNKIADIPPDEYSWRKYGQKPIKGSPHPRGYYKCSSVRGCPARKHVERCVEETSMLIVTYEGEHNHSRILSSQSAHT
The following text describes a protein:
Function:
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Subcellular Localization:
Secreted.
Sequence:
MKRLTCFFICFFLSEVSGFEIPINGLSEFVDYEDLVELAPGKFQLVAENRRYQRSLPGESEEMMEEVDQVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQEVKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEGHFDGVPVISKGQQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFAPDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRNDLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQIESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPSCCSGALYYGSKVVPDSTPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVENDPHFIIYLPKSQKNICFNIDSEPGKILNLVSDPESGIVVNGQLVGAKKPNNGKLSTYFGKLGFYFQSEDIKIEISTETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLHRVWKKHPVNVDFLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEASMEVKGQKLIITRGLQKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDYFVPQLYSFLKRP
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MKKGSFAADIYLSKCIENSLAVLPAWDKILWFGKPEVFPPQKERASKTMHDALYPFECRQAKLSYTGKFLVDICFQYDDGAVIREKINFGQFPIMLKSKLCHLRAADDSRKLIAHKEEPSEMGGYFILKGLERVIRLIILPKRNYPMSMARNSFRDRREGYSDKAVVIRCVREDQSAVSLKLYYLNNGSARLGFWIQGREYLLPVGIILKALVDTTDHEIYVNLTCCYNEERDRVKGSVGTQLVGERAKIILDEVQALSLFTRAQCLRHIGEHFQPVMTGMQNDSYKTVADAVLRDYIFVHLDNNHDKFNLLIFMLQKLFSLIDQTSVLDNPDSLQNQEVLLPGHLITIYLKEKLQDWLLRLQRLLQEETDGEKKKFELSSLADVKKAIDKNAPKQMGLAIENMLKTGRLVTQSGLDLQQRAGMTVQAERLNFLRFLSHFRAVHRGASFAGLRTTSVRKLLPESWGFLCPVHTPDGEPCGLLNHMTASCRITSYYDSKGNVKDFFKMRMSILNVMIAIGMTPSSPKLVQAGPPELLSVLLDGRIVGYMSSDLIEKAVTHLRRLKLSSTSSIPVDLEVGYIPLSMNGAYPGLYLFTSPSRFVRPVRSISAPAEEGNDLELIGPFEQVYMEISCPDGGDGGRKTVFPPTHREIHPTNILSVVGNLTPWSDHNQSPRNMYQCQMGKQTMGFSSQALNCRADQKLYHLQTPQTPIVRTKAYEKYCVDDYPLGTNAIVAVLAYSGYDMEDAMVLNKSSVDRGLCHGHIYQTETIDLTEQSVKSDRAQRLFRRSNLDKSSHRLIDSDGLPYVGQRINPNEPYCSIYNEITSQTTSMKLKGSEPVVVDYVSVDVKNKTHLQKANIRFRRSRNPVIGDKFSSRHGQKGVCSQLWPDVDMPFSGVTGMRPDLIINPHAFPSRMTIAMLLESIAAKGGALHGKFVDATPFSNTMKESESESSSLVDELGSMLTACGFNHHGVEVLYSGVYGTELTCEIFIGPVYYQRLRHMVSDKFQVRSTGQIDHITRQPIKGRKRGGGVRFGEMERDSLLAHGAAYLLHDRLHTSSDHHIADVCSECGSVLTSSIIQPPKRAVTILGLPPAREPKKVTCLACRSSKGMETVAMPYVFKYLAAELAAMNIKMTLKLSNGAGA
The following text describes a protein:
Function:
Helps regulate magnetite crystal morphology, probably in a single growth axis. May help control oxido-reduction reactions surrounding the crystal lattice of the forming magnetite mineral (Probable). Probably binds Fe(2+), may play a role in nucleation of magnetite crystal formation (Probable). Expression in a deletion mutant restores growth of spherical (wild-type) magnetite crystals. Increased protein levels allow crystal growth in the minor axis but not increased numbers of crystals.
Miscellaneous:
MISCELLANEOUS: This bacteria makes up to 20 cubo-octahedral magnetosomes of about 45 nm in diameter which contain membrane-bound crystals of magnetite (Fe(3)O(4)).
Subcellular Localization:
Magnetosome membrane; Single-pass membrane protein. Note=Tightly associated with magnetite crystals. Upon overexpression small amounts of a larger (full-length) protein is seen in the cell inner membrane.
Domain:
The isolated charged lumenal magnetite-interacting component (MIC, residues 298-314) binds Fe(2+) and Ni(2+); Ni(2+)-binding may not be physiological. Although it binds iron the protein fragment has no effect on magnetite crystal formation in an iron co-precipitation experiment, however mutating some of its residues decreases crystal size.
Sequence:
MQDLLLAKVESAMQASQVSALAGQTATVTKVSAATNLATITPTAAGQAPIIVKLDATRQVVELQALVGKTVMVGKTPAAIGGIGNWIALTPVTGAKAAAAATGAGQLVMMKVEGTAAAVNLPALAGKSFTIAQPPVAAGTKAAGMLYLNPVGGGDLIAINVQNAATQTGGLVGKTFVVAPSPVIGGTTGKFLVLKPLTAGAGKAVGGGAIAAKFIPAAVTGTGGAAAVGAGSASSLLTAGAGTVTPITAAGTGSAMLSAKGLGLGLGLGLGAWGPFLLGAAGLAGAAALYVWARRRHGTPDLSDDALLAAAGEE
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MEKVEEGYHTIHLWKGKVIEEKEVTYYIYNDMEILQIGRQVPIILRKAYLKLHPEVKGMKEEEIKLSFEIVFDKEYYFICKDKCEYWYWINKLSYFTHNIGVLGFPLLVAIRKSGWRVPNPIYRCIEYLEQNNGINVEGIFRMNGNAKDIDRIKDLVEHDQDIQFTQEDDCFIAASFLKLYLREMLEPLIPFNLYEQFIQLPKGGSNIKQFICQLPEANQDTLWFILHFLKKVVHNSEKNKMNAYNLSTCIALTVCSPQLTKSTDQMEYTLGAVESFSFLLTHFDEMFCEIEKRNMNKGMTLPTFPAFSPSCVDLSSIAQIIRNDIKKGFRSSYKKPSSGFSSPITSSPRGEDIQGEYQFNFNRGNSPSLSPPLKDDLKMSKTSFLHYSNRSRASCGDILEILSQENNTKKKTDSTTITSSQKQIETTIPGKICRSGPFFMNPDVRQKVIGPIKSPFDKCNGDVISKQSSM
The following text describes a protein:
Function:
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEVDSTGSGIPENSTRTDSSENVVACIPSSSGLSITLHPLVILNISDQHTRIRMQTENTDSSIALHQVIGALIGIQIGREVEILNSFELPCTLVDGQTIVDMSYFSFKQDQYKQVYPTMDFLGWYSTGMTPTQSEIYIHQQMCQHNDAPLFLQMHFIPSDVPAIELPITFYESLVDIVDGVPHTLFVKSKFKIETSDEELLAIEHVAHETSEEGQSKLTTHLIGQQNAICMLQSRVKALVQYMQDVEHGVLPKNHTLLRQISSLCNRLPTLQGNDFDNEFNVDYNDVLVMTLLAALTKGSHSLNELTNKINTIRTKRALHRPSTGSSGVAFGQSAGTLGMHI
The following text describes a protein:
Function:
Protein of the nuclear speckles that regulates RNA degradation and export from the nucleus through its interaction with MTREX an essential factor directing various RNAs to exosomal degradation. Changes the conformation of MTREX, precluding its association with the nuclear exosome and interaction with proteins required for its function in RNA exosomal degradation. Negatively regulates, for instance, the degradation of mRNAs and lncRNAs by inhibiting their MTREX-mediated recruitment to nuclear exosome. By preventing the degradation of RNAs in the nucleus, it promotes their export to the cytoplasm. U5 snRNP-associated RNA splicing factor which is required for efficient splicing of CEP131 pre-mRNA and plays an important role in centrosome maturation, integrity and function during mitosis. Suppresses intron retention in a subset of pre-mRNAs containing short, GC-rich introns with relatively weak 5' and 3' splice sites. Plays a role in DNA damage response.
Subcellular Localization:
Nucleus speckle. Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MALFPAFAGLSEAPDGGSSRKELDWLSNPSFCVGSITSLSQQTEAAPAHVSEGSPLTRSHLKSESSDESDTNKKLKQTSRKKKKEKKKKRKHQHHKKTKRKHGPSSSSRSETDTDSEKDKPSRGVGGSKKESEEPNQGNNAAADTGHRFVWLEDIQAVTGETFRTDKKPDPANWEYKSLYRGDIARYKRKGDSCLGINPKKQCISWEGTSTEKKHSRKQVERYFTKKSVGLMNIDGVAISSKTEPPSSEPISFIPVKDLEDAAPVTTWLNPLGIYDQSTTHWLQGQGPPEQESKQPDAQPDSESAALKAKVEEFNRRVRENPRDTQLWMAFVAFQDEVMKSPGLYAIEEGEQEKRKRSLKLILEKKLAILERAIESNQSSVDLKLAKLKLCTEFWEPSTLVKEWQKLIFLHPNNTALWQKYLLFCQSQFSTFSISKIHSLYGKCLSTLSAVKDGSILSHPALPGTEEAMFALFLQQCHFLRQAGHSEKAISLFQAMVDFTFFKPDSVKDLPTKGQVEFFEPFWDSGEPRAGEKGARGWKAWMHQQERGGWVVINPDEDDDEPEEDDQEIKDKTLPRWQIWLAAERSRDQRHWRPWRPDKTKKQTEEDCEDPERQVLFDDIGQSLIRLSSHDLQFQLVEAFLQFLGVPSGFTPPASCLYLAMDENSIFDNGLYDEKPLTFFSPLFSGASCVGRMDRLGCPRWTRGQNREGEEFIRNVFHLVMPLFSGKEKSQLCFSWLQYEIAKVIWCLHTKNKKRLKSQGKNCKKLAKNLLKEPENCNNFCLWKQYAHLEWLLGNTEDARKVFDTALGMAGSRELKDSDLCELSLLYAELEVELSPEVRGAATARAVHILTKLTESSPYGPYTGQVLAVHILKARKAYEHALQDCLGDSCVSDPAPTDSCSRLISLAKCFMLFQYLTIGIDAAVQIYEQVFAKLNSSVFPEGSGEGDSASSQSWTSVLEAITLMHTSLLRFHMKVSVYPLAPLREALSQALKLYPGNQVLWRSYVQIQNKSHSASKTRRFFDTITRSAKPLEPWLFAIEAEKLRKRLVETVQRLDGREIHATIPETGLMHRIQALFENAMRSDSGSQCPLLWRMYLNFLVSLGNKERSKGVFYKALQNCPWAKVLYLDAVEYFPDEMQEILDLMTEKELRVRLPLEELELLLED
The following text describes a protein:
Function:
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MKRKQKRFLQMTLLFTVALIFLPNVGLWSLYKDKHLVKSAEPGEQQTFPLGLGDGQFYSWTDGLRRKDWHDYESIQKEAMRSGKGEHGKPYPLTEEDHDDSAYRENGFNIFVSNNIALERSLPDIRHANCKHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPGSLIAEIILVDDFSEREHLKDKLEEYMARFSKVRIVRTKKREGLIRTRLLGASMARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVNRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYKVPSGTSLARIRNVAANLCVDSKHGATGTELRLDICVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDAISHNSPVTLYDCHGMKGNQLWGYRKDRTLFHPVSNSCMDCNPAEKKIFMARCDPLSETQQWIFEHINMTVLEKFNQHANS