lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
Subcellular Localization:
Nucleus.
Sequence:
MYKSKNTFRRLKRQKSNEVPISSSSSCSSNPAVRLDFISKKSRQCCYKPLGDLFALQQRRWDAMFDVSGTTDLSPPNLPCVTSSDLPCVTSSDLQCVTMMTSSGSFSRNNCDKVDEAFCSTRIAMQQSPTKDCCGDDVTVATAGSTSAVKAGLASDDMKNKNCDLNESTSLDTSFEDFIKDDDSLFSELNESEFNTTGANSCTKNNQSSIGDVTPLTLTKSSLSTTSTLETSITPSSALTMCPIKLSDHNNNNITTPLKLDSNTLPYYIENFKMMIVTTMGDAFHSHLFDESDRETVNLFLHKLTIPQQKLFTRLYLRKFCWLRLDQIKYNDISENLIDVLDSLVLLGLIDDVTKLTDLNTVLKCLLAPELKSLCKSLRLDAVSSKSDLIAAIINHSKTNSIKNFFKRTAVGDDSLPNVVLLRAKSILGHCYKLNKVRRSTFMRILILSSLNNTLSDDDLSAQQMIFQMLQTSNGKVKYPDYNINRTTKLFQSKNDLIMYEEILEHESTFWHKMEKKSYEDALKVYTDIRHRFEDYSLNDEIVTKHNRALPAFLRCYTASSAYIRILNKAVSLLQFLKRYEDAVKLLSQLLNQEVYHLDYRGRWFDRITLNLDFHLKNPTKALDYIKEALNDPWVKVGHRLDLLHRAKKILASKSKKLAEGSQESMREMIAIDVMNFIQAPLNVTTTGQQLFKVNAVAPSMWVVQGGGGGENDDVMMTAGRVEQVALDYYATIGYPEGIHGEGITLTTLFMLLSWDVVFMSSIPDVFYDNFQMAPLDFRSHDFYPKRKEKFHKRYQWISHASEEELDEMLEKCWSDNYGVICAWINWELFTGVEHVKGLVRSIGPEKLSSIFMRMAQNMRYVTGGVPDLIVWNPSQRRVKFAEVKGPGDKLSSKQILWLDFLLSIGLDAEVCHVKAENSKKIFKSVRENCDI
The following text describes a protein:
Function:
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
Subcellular Localization:
Secreted.
Sequence:
MNPLLQITGSLRPVALTLMLLMATAAFPTPGSWGKGFTGYELSSKLPSSIPDLDSIVNHAKYLEKTASDLKEEICRIHNLCDNSNEALAENNLLLPNITERDGCLPSSFNEETCLIKIISGLQDFDIFLNYMETEMEDNRFQTLKLSTTQLANTLKTVIKKTDLVPTTNPTTSSILLSELQSLTAWSRKVGFRLILWHYTRFIQGTVRAVRYLKTRSLDA
The following text describes a protein:
Function:
Protein-glutamine deamidase effector that inhibits the host cell cycle and other key cellular processes such as the actin network and programmed-cell death. Acts by mediating the side chain deamidation of 'Gln-40' of host NEDD8, converting it to glutamate, thereby abolishing the activity of cullin-RING-based E3 ubiquitin-protein ligase complexes (CRL complexes) (By similarity). Inactivation of CRL complexes prevents ubiquitination and subsequent degradation of the cyclin-dependent kinase inhibitors CDKN1A/p21 and CDKN1B/p27, leading to G1 and G2 cell cycle arrests in host cells. Deamidation of 'Gln-40' of host NEDD8 also triggers macrophage-specific programmed cell death (By similarity). Also able to catalyze deamidation of 'Gln-40' of host ubiquitin in vitro; however, NEDD8 constitutes the preferred substrate in vivo (By similarity).
Subcellular Localization:
Secreted. Host nucleus. Note=Secreted via the type III secretion system (T3SS).
Sequence:
MGDDIMPISNLAKESEVRAVKDIPCKNIETDNHLEIGLSSGLSRSKDTSKFKKNSINTIKLIDDIIALHNDPKGNKLLWNDNWQDKIINRDLANIFEKIDESVSELGGLEMYQEMVGVNPYDPTEPVCGLSAQNIFKLMTEGEHAVDPVEMAQTGKIDGNEFAESVDQLSSAKNYVALVNDRRLGHMFLIDIPSNDQETVGYIYQSDLGQGALPPLKIADWLNSRGKDAVSLNKLKKLLSREFNLLSDDEKRALISETLDIHKDVSNVELDRIKRDRGVDIYLTEYDVNNFYENIETLKSKLSNYDKKLSKPK
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MRLVLLNYGIWHDRRSALKFTDIDYFVFSDASKYVSIGMSPYMRDTYRYTPMLAILLLPTQYGFPSWGKYLFSISDLIAGWLMIKLLSRRISYKRSLIYSSFWILNPFVAIISTRGNCEAILGILSIALLYLIEKKSVWLASLILGFSVHFKIYPFMYGIAFLVYFSKPKKGSTFMEKFLSLLSINQLKIVVGSLFMFTICNLLMYYLYGSPFLEHTYLYHFGRTDHRHNFSLHHLNLYYESSFGAKASSLFAFLPQLSLCMLIPLVFGKKNLPGTLFAQTFAFVTFNKVCTSQYFMWYLVFLPLVLPNSKLLSKKGLICLSLWIIGQLLWLISAYNLEMLGKSVFIPLWLSGLLFFFFNVYELKIILDSL
The following text describes a protein:
Function:
Catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus.
Subcellular Localization:
Cytoplasm.
Sequence:
MDAMAPEEYASQSKLLQEFTNVPSIDSASILKTNDEDRSRAMFSISQPDLLANTNRKYVLYSHITTRAGTGTTSPDFQWSPFPTETTGVSATVPSPSGSKLLVVRNGERGCPTKLEIVCQSHVEKEIHVAGSVHGPLYTDEWFHGVSWNQEETLVAYVAEAPATPRPAFNRSGYTREEGCSEGDCSAWKGQGVWEEDWGETYSKKGRPSLFVLDIPRGEVVAAKGVPTSLSVGQVVWAPESPGGRHKYLVFVGWSERNGFFQNTARKLGIKYCSNRPCALYAAPCPIQGPEPPGNPPATTSDGKSGSGGAVARNLTPGFSSALFPRFSRDGRLLVFLSSKQAVDSGAHNATDSLHVINWPSDWKMDEQLDVTQVVPVVMCPEDDDGGCFPGLYCSSVLPDPWLSDGRTVILTSSWRSAEVILSVDVLSGKVARITPEDSCYSWRALALDGTNVLAVSSSPIDPPSISYGRRLAVTPAEGEARRWTWDEVTSPFMASNSKVKSLLLHHSVSILKIPVPSPSADLSDGGKLPLEAIFVSCSCKGSSRSPTVVVLHGGPHSVSVSSYSKSSAFLASLGFNLLVVNYRGTPGYGEEALQSLPGKVGSQDVEDCLAALDFAVEEELVDASRVAVVGISHGGFLTTHLIGQAPDRFAVAAARNPVCNLSLMAGTTDIPDWCYVVACGTQAKRYASEAPSPGHLRLFYQRSPIAHVSKVKAPLLMLLGGADLRVPASNGLQYARSLIERGGDVKIMMFPEDIHEINLPRSDFESFLNIGVWFKKHLNAVA
The following text describes a protein:
Function:
Virulence effector that plays a role in hijacking the host vesicular trafficking by recruiting the small guanosine triphosphatase (GTPase) Rab1 to the cytosolic face of the Legionella-containing vacuole (LCVs). Acts as an adenosine monophosphate-protein hydrolase (de-AMPylase) by mediating the hydrolysis of adenosine 5'-monophosphate (AMP) to 'Tyr-77' of host RAB1B, thereby releasing RAB1B from bacterial phagosomes and rendering RAB1B accessible for inactivation by LepB. De-AMPylation of RAB1B cannot take place when LidA is bound to RAB1B.
Subcellular Localization:
Host cytoplasm, host perinuclear region.
Sequence:
MVYYEIIKDIVFTYNLQFTHLIHNDRISEVNLGGVTMRSIITQICNGVLHGQSYQSGSNDLDKGNSEIFASSLFVHLNEQGKEIIKHKDSDDKIVIGYTKDGMAFQIVVDGFYGCERQAVFSFIDNYVLPLIDNFSLDLTRYPDSKKVTESLIHTIYSLRSKHAPLAEFTMSLCVTYQKDEQLFCAGFGIGDTGIAIKRNEGTIEQLVCHTEVDGFKDAFDNYSSANIDLVIERNSVFNTKVMPGDELVGYTYVPPMLEMTEKEFEVETVDGKKINKRIVRHLNLDPGNFDDKDPLFSQLLQVVKSKQKQLVEQAKETGQIQRFGDDFTVGRLVIPDQLLINQLRIHALSIGVSDGLLSYIKNENENKGFLGIYGFFTGADKNIEKATLYKNLIAKYQNNHFISLIILSALVSDSKTPLMTQYLVGYLDFPSKALLANKITELLLKELENPDMREILGSRLATDVIEELETKIIRYIHNPAGSDIHSTLNLWTADKIKAATNSSLTI
The following text describes a protein:
Function:
Involved in triacylglycerol (TAG) synthesis. Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAPPPSLAPDRGGGEPDDALRLRARAAAAAGDAPAPQQQQEQRHQEQQQQLLWYRASAPAHRRVRESPLSSDAIFRQSHAGLLNLCIVVLVAVNSRLIIENLMKYGLLIRAGFWFSGTSLADWPLLMCCLTLPTFPLAALMVEKLAQRKLISKHVVILLHIVITTSVLVYPVVVILKCDSAVLSGFVLMFLASIIWLKLVSFAHTNYDIRMLSKSIEKGVTHDISIDPENIKWPTFKRLSYFMLAPTLCYQPSYPRTTYIRKGWVVRQLIKCLVFTGLMGFIIEQYINPIVKNSKHPLKGNFLNAIERVLKLSVPTLYVWLCMFYCFFHLWLNILAELLCFGDREFYKDWWNAKTVEEYWRMWNMPVHKWVIRHIYFPCIRNGFSKGVAILISFLVSAAFHELCVAVPCHIFKFWAFIGIMFQIPLVFLTKYLQDKFNNTMVGNMIFWFFFSILGQPMCVLLYYHDVMNRQQAQTNR
The following text describes a protein:
Function:
Iron-storage protein.
Subcellular Localization:
Cytoplasm.
Sequence:
MLKTEMIDKLNEQMNLELYSSLLYQQMSAWCSYHSFEGAAAFLRRHAQEEMTHMQRLFDYLTDTGSLPRIHTVSSPFAEYASLDELFRATYEHEQLITQKINELAHAAMTSQDYPTFNFLQWYVAEQHEEEKLFKSIIDKLTLAGKSGEGLYFIDKELSTLDTQN
The following text describes a protein:
Function:
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.
Sequence:
MEFAFDINELLPDDITLVDGKVAPFRGKHTRDRFEFSTKQAELKKVIDMTGEASARAQGLRSPITSAMKLSHSDHKLYISKDASANSGKGAVVGLIKIGYKRLFLLDYQGNQHEVNPLCVLDFYVHESRQRKGCGKSLFQHFLKMEGIEPHMLAIDRPSPKFLSFLKKHYNLDKSIPQVVNNFVVFVEFFRDLQGM
The following text describes a protein:
Function:
This protein is involved in the initial step of iron uptake by binding ferrienterobactin (Fe-ENT), an iron chelatin siderophore that allows E.coli to extract iron from the environment. FepA also acts as a receptor for colicins B and D.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Does not bind histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.
Subcellular Localization:
Nucleus.
Sequence:
MGSELIGRLAPRLGLAEPDMLRKAEEYLRLSRVKCVGLSARTTETSSAVMCLDLAASWMKCPLDRAYLIKLSGLNKETYQSCLKSFECLLGLNSNIGIRDLAVQFSCIEAVNMASKILKSYESSLPQTQQVDLDLSRPLFTSAALLSACKILKLKVDKNKMVATSGVKKAIFDRLCKQLEKIGQQVDREPGDVATPPRKRKKIVVEAPAKEMEKVEEMPHKPQKDEDLTQDYEEWKRKILENAASAQKATAE
The following text describes a protein:
Function:
May be involved in the polar growth of plant cells via transportation of RNAs.
Subcellular Localization:
Nucleus.
Sequence:
MFSPGTMVEVSSKINEGEVVWVPSMVIKEFKEDDEYKYIVKDKSFSCEGKKARPNKTVDLSSLRPIPVSVDEYQLEENVEVFLDGMGWRHGRVMGSQERAIGTLSQKWYFVRLESTKKQLTFKQSDLRPLKVWEDGVWKVLQTRELSFTQGSGDKTGDSVRNANESDPPLTPPPGIITPPLKQIEAGTQRKALSKKTLPRNQNGSGNDSTLENENSEDNNRKRKREENLGCVASVEQDKPKDTTMVLPFEKKLRIWETLESMEVFKTVPQSPHFSPLLVESREDSREMSAVGMMLTFFGLLDEVKALQHNDPISFFISLTNSFAELEKHGFNVKAPQSRINKLLSLRDRQSKKTEELKDAEKVTAEKESVKAENKRKILELQRLNEEMDKEIAQSKSCAAKIVQQLDDVKLEFLATASAPW
The following text describes a protein:
Function:
Stabilizes dimeric photosystem II (PSII). In its absence no dimeric PSII accumulates and there is a reduction of monomeric PSII (By similarity).
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein. Note=The N-terminus is found within the thylakoid lumen.
Sequence:
MATITASSSASLVARASLVHNSRVGVSSSPILGLPSMTKRSKVTCSIENKPSTTETTTTTNKSMGASLLAAAAAATISNPAMALVDERMSTEGTGLPFGLSNNLLGWILFGVFGLIWALYFVYASGLEEDEESGLSL
The following text describes a protein:
Function:
High-affinity permease for basic amino acids.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDETVNIQMSKEGQYEINSSSIIKEEEFVDEQYSGENVTKAITTERKVEDDAAKETESSPQERREVKRKLKQRHIGMIALGGTIGTGLIIGIGPPLAHAGPVGALISYLFMGTVIYSVTQSLGEMVTFIPVTSSFSVFAQRFLSPALGATNGYMYWLSWCFTFALELSVLGKVIQYWTEAVPLAAWIVIFWCLLTSMNMFPVKYYGEFEFCIASIKVIALLGFIIFSFCVVCGAGQSDGPIGFRYWRNPGAWGPGIISSDKNEGRFLGWVSSLINAAFTYQGTELVGITAGEAANPRKALPRAIKKVVVRILVFYILSLFFIGLLVPYNDPKLDSDGIFVSSSPFMISIENSGTKVLPDIFNAVVLITILSAGNSNVYIGSRVLYSLSKNSLAPRFLSNVTRGGVPYFSVLSTSVFGFLAFLEVSAGSGKAFNWLLNITGVAGFFAWLLISFSHIRFMQAIRKRGISRDDLPYKAQMMPFLAYYASFFIALIVLIQGFTAFAPTFQPIDFVAAYISIFLFLAIWLSFQVWFKCRLLWKLQDIDIDSDRRQIEELVWIEPECKTRWQRVWDVLS
The following text describes a protein:
Function:
Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells (By similarity).
Subcellular Localization:
Cell membrane; Lipid-anchor. Cell projection, dendrite.
Sequence:
MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGIRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVMLQLEKKLFDYFNQEVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDARQGEQYMNTRCPAWCDRILMSPSAKELVLRSESEEKVVTYDHIGPNVCMGDHKPVFLAFRIMPGAGKPHAHVHKCCVVQ
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
Subcellular Localization:
Chromosome, telomere.
Sequence:
MSDHGDYAPESLPESPVLSRSGEGFDERPINGLYIDMAPFGLEKIWDYEPGGHHVVHLGDHLGREGEYKVIHKLGSGGFANVWLCQVLRNGVPHYVALKILMADYSKDDCPELRVERLRAVGLEKHICLPFDHFRIEGPNGSHLCFVYPVAGPRVSLIAHEFEDPDRSLRKMARQATEVMAALHSHGICHGDFTPSNILLKFEGLDGLPEDEVLKVLGEPVKVEVFTESGETPSDPTAPKYLVRPVKFRNVPLPYVVDEILVIDFGESYDVTNPPQELGIPGSYRSPELVLKNTPGFGSDLWALGCTLFEIRTGRKLFDMFDDDDDSYLFHMVEMLGALPEPWWSTTWTHRKEFFKDEADSLGRAVLVDALAREKSNLSVESPSVELALRRGLHYWDLGPGEEFSREIPPDEIEQLADLLKKILPYVPNRRLTATEVLEYEWFRRDEN
The following text describes a protein:
Function:
Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.
Subcellular Localization:
Nucleus.
Sequence:
MPNEFISQSLSTLTNTPLNIQKKLLPITKYRNQLLYAVEQNQITIVLGHTGCGKTTQIPQFLYEAGWASQNGIIGCTQPRRLVAKSVSERVSLELNSPPGSLCGYSIQFDHNVSEKTKIKYMTDGILLNEIFFDPLLERYSIVILDEVHERTLSTDLLLGVLKRILEKRNDFRLVLSSASVDANKLSQFFGQDKVCTMSIEGKLFPVETLFLQKPTENYVDSAIETVININSTYPPGDILVFLSGRKEIEYCIKKIEDSLIHASEDCQTLVPLPLHAGLTVDEQMRVFNIYDGDFRKVIFSTNIAETSITIDGIVYVVDSGFNKQRIYNPYTRTSKLINVPISKSSAIQRSGRAGRTMRGKVFRLYTEKAYSLMKEEFEADILNCDMSPLVLFLKGLGLKNILQFPFFVRPPTVHLMAALEDLYLLGVLDESGNLTDPLGIQISNSFLDANISKALLTSNQFGCTHEILSIASILTAGEVFYNPTSSSKNDAFVAHSSFFANEGDIITALNVFESFVGNKKDLQWCRKNYLNYQTLRQALDIRTHLVRFLNKFSIPTAQRLPSSDCSKILKCLLDGFVRNVAHLQNDGSYKTIGGKQVWLDSSSVLHEKKTPWIMYSSAVESETQIFVKNISKIESFWLDKYYKREK
The following text describes a protein:
Function:
Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.
Subcellular Localization:
Endoplasmic reticulum membrane.
Sequence:
MFNEIKSKKFWLGNQISRITINKDDYSVNLNKSPSLNRQTSPISESNHNTLTIIKKTKEVTDHSIDQSFKQVNSPLMFYLTNINQTSINNNNNSSNIINNRSCQQSQNNSQYTIDVPGNESFAQQSSIKLNEKDLLNQIVEAVFSKNIQLLTKIVLLLQKEYRTDILNLKDIHGNTPLLLAIKLQQQQNQFSTIRLLLSNGSDPTIKDTDGWSPIEETVAQKDLLTTSLLFDYLVSKKLFDMQQERNQIDQELLKINDFYLEMKWEFKSSLIPFISKFTPNDTFKIYKRGSSLRLDSTFAGKKNYKNKRRDLTVLYNPLMGSVQRKENSSNCKFVTILNRSKKIYYYPIQEIDPEEKNQILMDLLNCESVSGDMKIIQCELIKSKNFFGNYVNQKINNWICQKYEFRILTSQHFNKKHQSNYFMSQDQYFNQSLDQNPTSARFNLEQITSQIVGDQLLVNSPSFKQDNQNQQVKQNMQNSIKNEEDKKQQESCLLYINQEFPINFQQFLPIIKMLANGNEFISSLQTVLQNESVKQLLNDKGFPVRIEIPINFTIDAVVTFQAYKQIDIEDPEIKKLFQIPEDYLLVSRRDATKVMKRGKKRLFLANLFL
The following text describes a protein:
Function:
Hydrolyzes acetyl esters in homogalacturonan regions of pectin. In type I primary cell wall, galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions. Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MMMSALWVVLMLLGVTPWRSIHCLEVKQEKRLLVAMTLVPHAGSTGAVCLDGSPPAYHLHEGLGSGARNWLLQFEGGGWCNDVASCAARSKTRRGSTRYMNKLEVFSGILSNDSTANPDFYDWNRVKLRYCDGASFGGDSEFLNSTTALYFRGQRIWKAIVLDLLPKGLIQADKVLLSGCSAGGLATFLHCDDLTRFVPETATVKCISDAGFFLDVRDVSGQYTIRSFFSSLVSLQVRFLLLFVLSLTFRFAKLDVVPQGVQKNLNPNCTSSYGLFAYQCFFPQHALSYIRTPYFILNSAYDVYQFHHIFVPPSADPRGRWYSCKLNPMACSPIQIAILQGFRNEMLEALESFEGSQNGGLFINSCFTHCQSELQEAWFGPSSPRLHNKTIAEVVGDWYFGRGMAKEVDCPYPCDSTCDDLIPSNQGREVPSTTPLRICTIGCPLFVICLLLPLMII
The following text describes a protein:
Function:
Appears to control physiological cell functions rather than pattern formation during embryogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MDRSSAVGGCGGGGGLGVGVVTSSATALGPGGLTNGGGGVVSGALNGLEAMSAESTGLCLQDLVSAGTANGAGSAGSAESATTTSTALSSGSTGSSTVNGGGSSTSGTEHLHSHHSLHDSSSSVSISPAISSLMPISSLSHLHHSAGQDLVGGYSQHPHHTVVPPHTPKHEPLEKLRIWAETGDFRDSHSSMTAVANSLDSTHLNNFQTSSTSSISNRSRDRKDGNRSVNETTIKTENISSSGHDEPMTTSGEEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNAMNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKPFPWPVNPLGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVGAPCPYTTPANPYMYRSAAEPCMSSSMSSSIATLRLKAKQHASAGFGSPYSAPSPVSRSNSAGLSACQYTGVGVTDVV
The following text describes a protein:
Function:
Component of the intraflagellar transport complex B (IFT-B) involved in flagellar assembly (Probable).
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, flagellum basal body. Note=Localizes to the cytoplasmic and membrane-bound portions of each of the eight axonemes, localizing particularly at the flagellar pores and at the distal flagellar tips. Localizes to the basal bodies.
Sequence:
MNRLATGTAMHPAMTARTVTRGSVQQAVGGTAAMTQVALTARPITNMGMPGTRAVGGQRQVLDLGYYTSELRNLITATNKEAEALSKQTIELQKREGQLQRQQESLHAIQREVDELQGELQDILYSQSRLSENATLEDLRAEATEAESAASKTRNEANIAYKARVDAEERLRKNEASAVHLRTEMEAQIESTLGLQAAERYRSLNDENITLKQKESELRKELQEAAAVAANAYSFCTILSNYTSGGSISGQPGHIAMDERISGVDTNIQKAITLHRQIRAAKRELDAYKAKIKAAESHDPEQSLKQQLRNRFRVEQMETQSLVEEIKITESGVQQRKKLLEEITPDATVTITKEQKDLLKSVIKAEAFLVEFPNKKLALQTSIKQAQAEVVNLISRLPIPQGTVSVPGEENPGAIEAQLQQKSRELDRTTDTEMRVNAELRTYGDKVSALTDSLERLRADLRDAESIENVEAEESTLKTKLTSLKAMHEEETKTLEKSKGALRLIEDQIAANENAQLLRNLLDQLSANLQKKYAVELFIVQKTIESCYDEPKKKCLQLVSEINNILMGG
The following text describes a protein:
Function:
Together with SuyA, desulfonates sulfolactate to pyruvate and sulfite.
Subcellular Localization:
Cytoplasm.
Sequence:
MALDFSNATVKAWRRENGRVGVRNHVLILPVDDISNAACEAVANNVKGTLAIPHAYGRLQFGEDLELHFRTIIGTGANPNVAAVVVIGIEPEWTQVIVDGIAKTGKPVTGFSIEQKGDFETIRQAGWKAKEYVHWASELQKEDCPISDLWISTKCGESDTTTGLSSCPTVGNMYDKLLPQGIYGCFGETSEITGAEHICEKRAANPETARKFKEIWQAYSDDVIFAHQTDDLSDSQPTKGNILGGLTTIEEKALGNLEKIGRTSTYIDAMGPAETPSKGPGLYFMDSSSAAAECVTLMAAGGYVIHTFPTGQGNVVGNPIVPVIKISGNPRTLRTMSEHIDVDVTGVLTREMTIDQAGDALIEMIIRTANGRMTAAEALGHREFSMTKLYRSA
The following text describes a protein:
Function:
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MATFFGEVLSVYSRAVEEDEYEDMTNENEEDEQIRREIEEKRSVEVCWLLGSQDGPLQCSDLIIGAGPNASGFIRAYLLSTVGWTAVAWLSFWNERSRGSERPTVVPGPGEPSCVLYRLESCPTVLICQCQGFVAEDQLFQFTEKVFSCVQTRDLNVTILSDCSSADYKTSDYLSGSSTPFLRCLKTSTYTHTVTCPPLEQPNICSGLAAAVLSHCQVHQISAVLYQCYSDVLHPDSASMQMFAATLSSVLKLEQSLSADVLQRVTRVSEIQSNLYT
The following text describes a protein:
Function:
Transcription factor probably involved in the development of the brain and the sense organs. Can bind to the bicoid/BCD target sequence (BTS): 5'-TCTAATCCC-3'.
Subcellular Localization:
Nucleus.
Sequence:
MTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGAS
The following text describes a protein:
Function:
Plays several crucial roles in viral infection. Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein. May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation. Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle. Can also catalyze the renaturation of complementary single strands. Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments. This process is driven by the protein which can form double-helical filaments in the absence of DNA.
Subcellular Localization:
Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework-associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).
Sequence:
METKPKTATTIKVPPGPLGYVYARACPSEGIELLALLSARSGDSDVAVAPLVVGLTVESGFEANVAVVVGSRTTGLGGTAVSLKLTPSHYSSSVYVFHGGRHLDPSTQAPNLTRLCERARRHFGFSDYTPRPGDLKHETTGEALCERLGLDPDRALLYLVVTEGFKEAVCINNTFLHLGGSDKVTIGGAEVHRIPVYPLQLFMPDFSRVIAEPFNANHRSIGEKFTYPLPFFNRPLNRLLFEAVVGPAAVALRCRNVDAVARAAAHLAFDENHEGAALPADITFTAFEASQGKTPRGGRDGGGKGAAGGFEQRLASVMAGDAALALESIVSMAVFDEPPTDISAWPLFEGQDTAAARANAVGAYLARAAGLVGAMVFSTNSALHLTEVDDAGPADPKDHSKPSFYRFFLVPGTHVAANPQVDREGHVVPGFEGRPTAPLVGGTQEFAGEHLAMLCGFSPALLAKMLFYLERCDGAVIVGRQEMDVFRYVADSNQTDVPCNLCTFDTRHACVHTTLMRLRARHPKFASAARGAIGVFGTMNSMYSDCDVLGNYAAFSALKRADGSETARTIMQETYRAATERVMAELETLQYVDQAVPTAMGRLETIITNREALHTVVNNVRQVVDREVEQLMRNLVEGRNFKFRDGLGEANHAMSLTLDPYACGPCPLLQLLGRRSNLAVYQDLALSQCHGVFAGQSVEGRNFRNQFQPVLRRRVMDMFNNGFLSAKTLTVALSEGAAICAPSLTAGQTAPAESSFEGDVARVTLGFPKELRVKSRVLFAGASANASEAAKARVASLQSAYQKPDKRVDILLGPLGFLLKQFHAAIFPNGKPPGSNQPNPQWFWTALQRNQLPARLLSREDIETIAFIKKFSLDYGAINFINLAPNNVSELAMYYMANQILRYCDHSTYFINTLTAIIAGSRRPPSVQAAAAWSAQGGAGLEAGARALMDAVDAHPGAWTSMFASCNLLRPVMAARPMVVLGLSISKYYGMAGNDRVFQAGNWASLMGGKNACPLLIFDRTRKFVLACPRAGFVCAASSLGGGAHESSLCEQLRGIISEGGAAVASSVFVATVKSLGPRTQQLQIEDWLALLEDEYLSEEMMELTARALERGNGEWSTDAALEVAHEAEALVSQLGNAGEVFNFGDFGCEDDNATPFGGPGAPGPAFAGRKRAFHGDDPFGEGPPDKKGDLTLDML
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.
Subcellular Localization:
Nucleus.
Sequence:
MLDHSDKVSKPRAEDMIEQNKTSSSNEKKTCAHCGTSKTPLWRGGPAGPKSLCNACGIRNRKKRRGVEDKKQQSKKSSSGGGGDLKQRMMDFEMGKRSTVEKQRRKLGEEEQAAVLLMALSYGSVYA
The following text describes a protein:
Function:
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus.
Sequence:
MACVHVLVGQCGNQLGAHFLTALTDEARRCSDEDYASQISADHFRPAPTQKGIRRGGVSNGNSGHHDEPPLPRSVMIDMEPKVVESVVTGVNDGGAFQVRAEQCVTRDEGSGNNWAFGYYEQGRSRCDEIVESLRRQSEARGAAHSFHIVHSVAGGTGSGVGCLVSDAIRVEFPRALLLHTAVWPFATGEVVTQWYNCVLAMSALRESADAVFVAHNDDFDVSARPLQKAVNGRTSEVSFDTINHEIGRLLLDLHLPKKLYPVPSTAPEKKPHPQSTFPASRTTSSTGAMASLRCGGLTDVVEAVALDPALKFFSGLALPVTPPDNRVVAPEATSWYPLLCEASRRTSELFVPAPSGDNNTSNNLSTAFIEQRPLLWSLRGPAACSEGLAHLREVLSRSTPTPDGRELYVPPSALLLHEERLLGRRAHVSVFGPTHNIGLRLASALERAEDLLRVSAYVHHFSRYGVGEEELRDAVVRMWDTAAAYGAA