lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N-glycans. Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MRCPKCLLCLSALLTLLGLKVYIEWTSESRLSKAYPSPRGTPPSPTPANPEPTLPANLSTRLGQTIPLPFAYWNQQQWRLGSLPSGDSTETGGCQAWGAAAATEIPDFASYPKDLRRFLLSAACRSFPQWLPGGGGSQVSSCSDTDVPYLLLAVKSEPGRFAERQAVRETWGSPAPGIRLLFLLGSPVGEAGPDLDSLVAWESRRYSDLLLWDFLDVPFNQTLKDLLLLAWLGRHCPTVSFVLRAQDDAFVHTPALLAHLRALPPASARSLYLGEVFTQAMPLRKPGGPFYVPESFFEGGYPAYASGGGYVIAGRLAPWLLRAAARVAPFPFEDVYTGLCIRALGLVPQAHPGFLTAWPADRTADHCAFRNLLLVRPLGPQASIRLWKQLQDPRLQC
The following text describes a protein:
Function:
Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.
Subcellular Localization:
Nucleus.
Sequence:
MSSTVAASTMPVSVAASKKESPGRWGLGEDPTGVGPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSMAQVHLDAMETGSDPRSEPVVASPALAGPSPRGPTSVSATRAMGHHFMASLITAETCAKLEPEDAEENIDVTSNDPEFPASPCSLDGIHETSARLLFMAVKWAKNLPVFSNLPFRDQVILLEEAWNELFLLGAIQWSLPLDSCPLLAPPEASGSSQGRLALASAETRFLQETISRFRALAVDPTEFACLKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFLTAERIELLFFRKTIGNTPMEKLLCDMFKN
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MGCFWSKNQPPSDGELQNILGKPLEDIKKLYSFGKELGKGNLGTTYMCEEILTGRSYACKSIQKGELKSEEDKEAVKKEIEIMFRLSCQHNIVSIKSVYEDRECIHVVMELCGGGELSSRIEAHSYYSEKDSAGILKSIVNALQTCHSMSVIHRDVKPENFLFSSEVENTVLKAIGFGSSVNIKQETELKRKVESKYYLAPEVLLGKSNGKEIDIWSAGVILYLLLSGKHPFEAEHSWIKIQAPYKPIDNVLVLRMKRFGAMNKLKKLALNVIVEGLEEELIKDDKDRDFKNMDTDGTGSITYGELRNGLNAPRSHPNISLSEAKQLMEAADVDGNGRMDLYEYISATTETNVLVTDENLHKAFQFFDKDGSGYITKNNLKHVVGDEANAKDIISEVDTDNDGRINYEEFCAMMRDGKLQPQGRRVRIN
The following text describes a protein:
Function:
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore; As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex. Lysosome membrane.
Sequence:
MFVARSIAADHKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSENGNWHCTASWKTHSGSVWRVTWAHPEFGQVLASCSFDRTAAVWEEIVGESNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHMGLMLATCSADGVVRIYEAPDVMNLSQWSLQHEISCKLSCSCISWNPSSSRAHSPMIAVGSDDSSPNIMGKVQIYEYNENTRKYAKAETLMSVSDPVHDIAFAPNLGRSFHILAVATKDVRIFTMKPLRKELSSSGGVTKFEIHTVAQFDNHNSQVWRVSWNITGTVLASSGDDGTVRLWKANYMDNWKCIGVLKGDGNPVGNSYQGFFGSSVGSAGQSLQNSVNGTPSSGRKHS
The following text describes a protein:
Function:
Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
Subcellular Localization:
Cytoplasm.
Sequence:
MDESFFFQQHGLINHALSLLVKRNFGDEAWDSIREKIGMSNSSYFIQRKVYADDVTFELVKTASEVLGIQVNDLLETFGRFFVSFCEELGYKRILEVMGSNLFEFINNLDSLHDHLATIYSGMKAPSFRCKYNSDNDTITLHYYSTRPNLEYIVVGIIKEVAEKIHLIDINMEVVKTRQNQLDDIQFLIYSKNPAKARIKCHDRLRRSIASSTRKQTKNSETCNFIAPTTFCRAFPFHVLFDRDLSIQQLGHVIERMIPGFYLGDLKMDKIFKIVRPVIQFDFHSILSHINTVFVLTMKPLCPSFLEQYLQWSDVRFKGQMIYLEENEMMLFHCSVSISSLEELRSHGLYLCDIPRYDASRNVILRSDHFRHDYQMMLQLETLNDRLADTYQQLQKEKDLTGELLYSVMPPSVAKQLRLGHKAVPSKHSMASVMFCKVSTFQDITTNIEPTKLIALLNDIYITFDQIIDRQGDEFYKVETLGDKYMVASGIPQYQSTHAKSIVKVAIEMMNTSQKRGNKKLSTMLSIGIHSGEIVAGVIGEKLPRFSIFGDTVNIASRTLTTGVPGVINITEDTFRCLDSPKYFENKYLLSCLGPVNMKGRSTPLTCYIVSHQAKSPASTANGQTNSCPSTIN
The following text describes a protein:
Function:
Intrinsically disordered protein that potentiates the transcriptional activator activity of JUN. Protects cells from stress-induced apoptosis by inhibiting reactive oxygen species (ROS) production and via regulation of the MAPK signaling pathway.
Subcellular Localization:
Cytoplasm. Nucleus. Mitochondrion. Note=Translocates to mitochondria in response to stress.
Sequence:
MSARVRSRSRGRGDGQEAPDVVAFVAPGESQQEEPPTDNQDIEPGQEREGTPPIEERKVEGDCQEMDLEKTRSERGDGSDVKEKTPPNPKHAKTKEAGDGQP
The following text describes a protein:
Function:
Induces host cell lysis. Inhibits host MurA activity thereby blocking the synthesis of murein precursors necessary for the host cell wall biosynthesis. May be responsible for the attachment to the host pilus. Makes extensive contacts with the viral genome.
Subcellular Localization:
Virion. Note=A single copy of the maturation protein is present in the virion.
Sequence:
MPKLPRGLRFGADNEILNDFQELWFPDLFIESSDTHPWYTLKGRVLNAHLDDRLPNVGGRQVRRTPHRVTVPIASSGLRPVTTVQYDPAALSFLLNARVDWDFGNGDSANLVINDFLFRTFAPKEFDFSNSLVPRYTQAFSAFNAKYGTMIGEGLETIKYLGLLLRRLREGYRAVKRGDLRALRRVIQSYHNGKWKPATAGNLWLEFRYGLMPLFYDIRDVMLDWQNRHDKIQRLLRFSVGHGEDYVVEFDNLYPAVAYFKLKGEITLERRHRHGISYANREGYAVFDNGSLRPVSDWKELATAFINPHEVAWELTPYSFVVDWFLNVGDILAQQGQLYHNIDIVDGFDRRDIRLKSFTIKGERNGRPVNVSASLSAVDLFYSRLHTSNLPFATLDLDTTFSSFKHVLDSIFLLTQRVKR
The following text describes a protein:
Function:
[Isoform a]: Probably forms a complex with isoform b that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP) (By similarity). Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and mocs1b catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cPMP (By similarity); [Isoform b]: Probably forms a complex with isoform a that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP).
Sequence:
MSCRAGKKLFQWSRVKSSTEEIVKQLTVPLREHAEPILTLTPEQKREAVRLKIQEIEHTKGQPPFFDMFMREHTYLRISLTEKCNFRCLYCMPAEGVPLKPKDKMLSNSEVLRLVKLFAAHGVDKVRLTGGEPTIRKDIVHIVEGISSTPGIKEVGITTNGLVLQRFLPQLRDAGLTKINISIDSLDREKFAKMTRRDGFDKVWKAIELARGYYPKVKLNVVVLKHQNENEVVDFVNLTKDRNLDVRFIEFMPFGGNEFKNDNFIGYREMLNLIVDKYGDGVIRLSDSPNDTTKAYKIDGFQGQFGFITSMSDHFCNTCNRLRITADGNLKVCLHGNSEVSLRDRIRCGDSDEQLSEVIQKAVNNKKARHAVFRNGRSEEPAKSSNDSYRGLTPVTSASSILVHLPSSSLYHSHLHSSRHFFISQIRCFSTTYSVSSITHLLTHVDNNGNAKQVDVSQKDTSTRTAVARGTIILTAEISRQISENTIKKGDVLTVAKIASILGAKQVANLIPLCHPIRLDFVDTVFNHDIENSKLHCISTARCSGNTGVEMEALTACTIALLTVYDMCKAISQKMMLTNIYLVHKSGGKTTYTIDNENQI
The following text describes a protein:
Function:
Deubiquitinating enzyme that specifically hydrolyzes 'Lys-63'-linked polyubiquitin to monoubiquitin. Required for the stability and translation of a subset mRNAs with a high abundance of rare codons by mediating deubiquitination of 40S ribosomal protein RPS10/eS10, thereby antagonizing ZNF598-mediated 40S ubiquitination. The abundance of rare codons in mRNAs can limit the translation rate and can lead to ribosome collisions that trigger activation of ribosome quality control (RQC) pathway by ZNF598. OTUD1-mediated deubiquitination prevents activation of the RQC and subsequent dissociation of ribosomes and stimulates formation of polysomes and translation.
Sequence:
MPPAVTQAAFGRSIGQPKTQDYYIYPKKGFQRNNNDINDDENHPPQKSARNAPKVRNVPIKLIKRGSQEGEPPPSPEPAFTEITFNRQANMCRTPGDRKVVSEEDVDDKLTSRRVPITVKHEIRVPRSFEREKDVFAWDYDFEKDAPFGIRSTGIDGDGLWGVGGKSLRELLRNSYERPEERRHQRDVSVSGSTGNGSVVDSDIEEAGDEVFCWERERGDVRRAQNGEDGQGKKSKTASITSSIRNRKIPPGEGKSTPEDSNGSVERVRERKPCVERVDYTKQNTERLSNSRLDAILSEVKLQDKSLAKSGACRYPIAGDGNCLYRAVAHAVYGNQALHTDLRRRTVQYMRDHRDDFAPFLDCDADSYIAKAAKDGEWAGYTEMVALMRLLNVDVRLTTGGTPGQPDVTSGVHRVREEVDVKGNKTVWLSWLSHGHYDAVEKIS
The following text describes a protein:
Function:
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MESLQQLQQQLGLMAWPLFICSALTVMLLAERLFQVLLSLTVGKGAIRHALQATSPKNPKQLAELTEHFASKRPVLYRGVAMLLAHHQFDKSLREDAAGIWLQEQRHQFNSGLRLLTLIGVISPLLGLLGTVLGLIEMFKGVAATTGSITPNVLADGLGVAMYTTAAGLLIAVPAVAGAQLLSLWADRTMAKLEHTLNYVNLWLEGMTLHADASLTVVTPQEATTENL
The following text describes a protein:
Function:
Possesses E3 ubiquitin-protein ligase in vitro.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MASSAPAWVPYEPTRDCSQGLCSMYCPQWCYFIFPPPPPFDVAGTSADDSSGPVFSPLVIAIIGVLASAFLLVSYYTFISKYCGTVSSLRGRVFGSSSGGAAYGGGAGSGGRHGHGQSRSHESWNVSPPSGLDETLINKITVCKYRRGDGFVHTTDCSVCLGEFSDGESLRLLPRCSHAFHQQCIDTWLKSHSNCPLCRANITFVTVGLASPEPEGCAPGETGGDNTHEVVVVMDGLENLCEEQQEAVSRASTADDDHDAKDVAEGMEEANGAAEIREEGSPPKRGASSFDLHRDNRMCIADVLQESMEDELTAARESGLLAGGAGTSRRCHGENSKGRGGRSRRALQLQDAMEALPGKRLPSGGRSCFSSKSGRGKDSDHPM
The following text describes a protein:
Function:
Not known. One of the major polypeptides produced on heat shock.
Miscellaneous:
MISCELLANEOUS: Present with 19300 molecules/cell in log phase SD medium.
Sequence:
MSFNSPFFDFFDNINNEVDAFNRLLGEGGLRGYAPRRQLANTPAKDSTGKEVARPNNYAGALYDPRDETLDDWFDNDLSLFPSGFGFPRSVAVPVDILDHDNNYELKVVVPGVKSKKDIDIEYHQNKNQILVSGEIPSTLNEESKDKVKVKESSSGKFKRVITLPDYPGVDADNIKADYANGVLTLTVPKLKPQKDGKNHVKKIEVSSQESWGN
The following text describes a protein:
Function:
Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MKTLKRATKLRILKKRFRSIAMDSNHQNNYKLNKTEKKFLRKQIKARHTLLRHEGIETVSYATQVLVVANGGLGNGVSRNQLLPVLEKCGPVDALLMPPNKPYSFVRYKTTEESERAYVTLNGKEIVDDLGQKIILYLNFVEKAQWKELGLQALPPGLMVVEEIISSEDEKMLLESVNWTEDTENQNFQKSLKHRRVKHFGYEFHYENNNVDKNKPLPGGLPDICDSILEKWLKEGFIKHKPDQLTVNQYEPGHGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGVTVPVMLPRRSLLVMTGESRYLWTHGITPRKFDTVQASKSHKSGIITSDVGDLTLSKRGIRTSFTFRKVRQTPCNCSYPLVCDSQMKETPSSFPESDKEASQLEREYVHQVYEEIAGHFSSTRHTPWPRVVEFLKALPSGSLVADIGCGNGKYLGVNKELYMIGCDRSQNLVDICRERQFEAFVCDALAVPVHSGSCDACISIAVIHHFATAARRVAAIQELVRLLRPGGKALIYVWAMEQEYNNKKSKYLRENRVSQGKKEEINSDTSVQELLVEQMPVVGNQDSACSVPSTNDFQKGGCDSRKVTDSKLPVHTNRTSFHSQDLLVPWHLKGNPGKNKLVEPFGPVGSHDPSPVFHRYYHVFCAGELEAACQTLSNVSVLQSYYDQGNWCVILQKV
The following text describes a protein:
Function:
Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4-naphthoquinone.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTESSPLAPSTAPATRKLWLAAIKPPMYTVAVVPITVGSAVAYGLTGQWHGDVFTIFLLSAIAIIAWINLSNDVFDSDTGIDVRKAHSVVNLTGNRNLVFLISNFFLLAGVLGLMSMSWRAQDWTVLELIGVAIFLGYTYQGPPFRLGYLGLGELICLITFGPLAIAAAYYSQSQSFSWNLLTPSVFVGISTAIILFCSHFHQVEDDLAAGKKSPIVRLGTKLGSQVLTLSVVSLYLITAIGVLCHQAPWQTLLIIASLPWAVQLIRHVGQYHDQPEQVSNCKFIAVNLHFFSGMLMAAGYGWAGLG
The following text describes a protein:
Function:
Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA. May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly.
Subcellular Localization:
Nucleus, nucleoplasm. Note=Granular component of the nucleolus.
Sequence:
MASLLAKDTYLQDLAKKICAQPGPERQRSTWGVRTKGSEAAGAPKKKRKKTQKKSPEQEQKAMDHKTKALGKKPPTSSRPKNPMVSKQEKGLSSLGSPKDSQGTARESVFALDFLRQRLHEKIQLARGQGSTKELSAATLEKRQRRKQERERKKRKRKERQAKQQVAEAEKKEEPVEVTPKMACKELQESGLIFNKVEVTEEEPASKAQRKKEKRQKVKGNLTPLTGRNYRQLLDRLQARQGRLDELRDQDAAKAQELEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRKWEKRSEHVVEKMQQRQDKRRQNLRKKKAARAERRLQKAHKKGRVLPQDLERAGLS
The following text describes a protein:
Function:
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.
Sequence:
MNKQPGEQPVSCATSTGKSEKERQKDEPPRSRAEAGMMRGGGRLPQPRDTPMEVPNMIAAMPIQMTGFVDLAPHTILDVLAQTTSLMIVQCLEPLEIFTGIETPNRYVVHDMYCRPLLYCMERSSFFARQHQGSQRNFAMQCMDIFGAPVMNCFRSRPCCSCDDFLATEFLGQRIGMMKRECCDDNFHLVGTGSNEPLLVRSPGCACCGGTQVFPVMTYNGAKIGEIVRLYPGFMQEWYTDADTYIVHFPPDLPPILKILLISSTFLIDYTFFENRGGNQRGGYGHGGYGYY
The following text describes a protein:
Function:
Involved in pre-mRNA splicing. Required for the SF3b integrity and prespliceosome assembly.
Subcellular Localization:
Nucleus.
Sequence:
MAEKQRQLKLQKIYKQKYIGLGDESTTREQWQRNVRNDTLNTLQGHSASLEYVSLSRGDLSIRDTRIHLLKSMSPGYKAYLREER
The following text describes a protein:
Function:
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Sequence:
MKKLAELTNKEIINLLSRQAHVELQSSFLYLQYAYWFDNNNFEGIGKFFKAESEEERKHSVQIFDYLNVRGVQVAIDPQQAAFSNLKTHFEKPGEYFEAYLAREHLNYSLLDQIGKQAQQTEEILTHKFIGSMLEDQASSVDEAEKLYAKAQAYSAFPGLFYHLDAQIEKGSQSFDTWRAKQS
The following text describes a protein:
Function:
Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
Subcellular Localization:
Nucleus.
Sequence:
MKYIDEVDLELVNQELNFHSPDNNLVIKGGCELFTTKPIGSDRKLFKTIDKHLDQIIEDNQFSRSIEREKRNSISSMFGSNASSPDLRRHSAISISDMRRRASSNSGSINFNRNSLPKNEQHNNNNNTSLLSQSLNDSGVIDDNEHAIDESPFGPLKNVTTRKTFAYLIAILNSSFPDQDFTNLQPTTENFYRIESPDELVHRFNNVLLSLGKKEDILNWIWDIINSYMDVLPSKNSSPYIAAQNSGGSRHGSFSASTGNSSPPSNSSYETCQIYQFQPSDESILEDLTYPYQPMWSYYYFIYNKKKKRVTFIHIAAINKADYSNGNGNQGSGNSENSSNRAKVINSDGEEEYDVNDDYGAVVDDDDDDENEDVVGGLEI
The following text describes a protein:
Function:
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MRLWNRFSRLGNLLCACAACGCSFTPWRCSSSPLLSSFSAYNMSSGNRVTSSVGGSSGATEVCPSHTPLSSSTLLRYTIAPSEPTMGSPWQTSEESASRRLAALTSYPPSNIRNVAVVAHVDHGKTTLSDVLLRRTGVLKGSVNAGAYTDRLLVERERGITVKSQTCSMFLKYGGSEFLLNLIDTPGHVDFQYEVSRSVRAAQAVLLLVDVAQGIEAQTMSHFHMALDQGLAIIPVFTKMDCVLNDTTVDAALQQLEDSTGLLRSEVVFTSAKEQLGVEALLQAIIERVPSPSGAIGLSDVCQLPPLLPGSTARVAMEAEMVPLRAILLDSWTRECGGGLYRPPSKTSSALSGNVKIDEDKDTVTCLVSVIDGTLTARTNILLYHSQKRYEAREVGVIHPELRPTGALTVGMVGYVVFTRVQREDFSVGETLYTLPTRKFTRGGIAPVPGFRRVHPVVFAGFYPDEGEYVTQLREAVEKLRMNDPAVTVEPLECQALGSGLQLGFLGVLHMQIFQERLLSEFGQRVLVTPPVVQYKYREAAGGDDQPPKPLSVHTWRWLHEGVSCYMEPHVTATVVTPSEYAQIIDGEAQRHYRGKQLDMRVMDDARVLLRYKMPLADMVRGFFTFVKSQSHGYASLEYDELVYEEADLVRVDIVVQKARISALAVICPRHEAPSVGKRIVASLKSNLTRTAVDIPLQALVGSKVVARETVRAYRKDVTAKIHAGDISRKQKKWNDQKKGKERMARRTVGGVTLDQSVLAAAMGATAL
The following text describes a protein:
Function:
Involved in the formation of a rigid and insoluble egg chorion by catalyzing chorion protein cross-linking through dityrosine formation and phenol oxidase-catalyzed chorion melanization.
Subcellular Localization:
Secreted. Note=In the chorion layer of the mature eggs.
Sequence:
MAKKVLLLSLYSAVLSTWFGFGYVQCKLPTSRSEIPNFDYTVAQQPDQSDACEQNEVCMVSVECILDAKKKAILKPCSTVPSVDGVCCPSSEYNGTSSRVQQNSEEHAADHLVLQAIHEGRREYDEKLRFEDEHRAVMTAKEKPEAMFHRMFLPGGLKTHGKEVVDAEEQANVYGHVFASRKYAELTNMTLKQRQGDRFARIPRAIRKRCLPPVPCNPHSRYRTIDGSCNNPLPDRTSWGMEGYPFDRVLEPAYEDGVWAPRIHSVTGNLLPSARVISVALFPDEYRPDPRLNILFMQMGQFISHDFTLSRGFTTKHGQAIECCTPNCTAPLFGPHRHFACFPIEVPPNDPFYSRFGVRCLNLVRIRLAQGPECQLGYAKQADLVTHFLDASTVYGSTNDVAAELRAFQQGRLKDSFPNGIELLPFARNRTACVPWARVCYEGGDIRTNQLLGLTMVHTLFMREHNRLAVGLSKINPHWDDERLYQEARRILIAEYQNVVYNEFLPILLGHERVQQLGLADPFDTYTNYYDPNLRPMTLAEVGAAAHRYGHSLVEGFFRFLTRESPPEDVFIKDIFNDPSKTLEPNSFDVMMFSFNQQPMEQMDRFLTYGLTRFLFKERKPFGSDLASLNIQRGRDFAVRPYNDYREWAGLGRITDFNQLGEVGALLAQVYESPDDVDLWPGGVLEPPAEGAVVGSTFVALLSAGYTRYKRADRYYFTNGPEVNPGAFTLQQLGEIRRTTLAGIICANADHKEDFYQAQEALRQSSADNVPVPCTRYDTVNLGLWREEGF
The following text describes a protein:
Function:
Functions in the second step of pre-mRNA splicing. Involved in splicing intron which are longer than 200 nucleotides.
Subcellular Localization:
Nucleus.
Sequence:
MLVANYSSDSEEQENSQSPNIQPLLHTENLAPAVVDNVKDDLIVSKGGNSRELARNVPVNEMVQPALGPANPFVTKEQDSIKNSITGYAEREYVPNFVFNQEYYANTHAIYGKRNFDDNEATTSTDLKRKSQKIKERREDPGDPSILEGDGAYKGPWAGYGSEQSSSPLEYSEYEEVESLDVKSEKDTESNNLGQNELLKEQLATPEVETHRSKEETILHKDRLFDYQNRSYMHVPNDVGINLSEEPGEQTCYIPKKHIFTWKGHTKGISCLRFFPISGHLLLSGSMDNQIKIWEVYHDRSLLRTFQGHARPIRDLSFSQDGRSFLSTSFDKTIKLWDTELGKCLNCFNSDRLTNCVKFQVDPDKPNEFLAGTADKRILQFDIRSPDIVQAYDHHLGGINSITFLENGKRFVTTSDDSSMRFWEYGTPVPIKFVADIAMHSMPRVALRPNGKSIACQSLDNCIYVYSAYEKYRQNKKKVFKGYSCSGYSLEVGFSPDGRFVFSGDSSGNACFWDWKTCKLMAKLPAHSGPVQSMAFHPQETSKVATSSIVDGSIKYWD
The following text describes a protein:
Function:
Binds preferentially double-stranded telomeric repeats, but it can also bind to the single G-rich telomeric strand.
Subcellular Localization:
Nucleus. Nucleus, nucleolus. Chromosome. Note=Localized to the nucleolus during interphase.
Domain:
HTH myb-type domain confers double-stranded telomeric DNA-binding while the H15 domain is involved in non-specific DNA-protein interaction and multimerization.
Sequence:
MGAPKLKWTPEEETALKAGVLKHGTGKWRTILSDPVYSTILKSRSNVDLKDKWRNISVTALWGSRKKAKLALKRTPLSGSRQDDNATAITIVSLANGDVGGQQIDAPSPPAGSCEPPRPSTSVDKIILEAITSLKRPFGPDGKSILMYIEENFKMQPDMKRLVTSRLKYLTNVGTLVKKKHKYRISQNYMAEGEGQRSPQLLLEGNKENTPKPEENGVKNLTKSQVGGEVMIMGMTEKEAAAAAARAVAEAEFAMAEAEEAAREADKAEAEAEAAHIFAKAAMKAVKYRMHSQTR
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Sequence:
MFSCFNNLGLDYCYQCMHGPEGCMVPSRQGDGGELYAHSEELEAKLRGLAKKESLEIEKSLENDKKTYGSHIKILILGGPSSGKSTIFKQMQIIHSNGFKTEQELIQYRGLIDTNIRQTYRQLVSGARVVGISLESLESLVHDINKVYAPMAADEFSIRTIPDVVEPLTAFWNSREIQEVYKRRYEFELLDSTKYYLENLNRISKSDYLPNEEDIVHSRKATVSINSIVFQYTGVSLLMVDVGGQRSERKKWLHLFDDAKVVIFVIDLTGYAKKSEESRTELSRFPNFFNEIGNDAFDMKVALKIFNDVAGSHALANAVFLLFFNKVDLFKELLPQVSLQPCFSKFAEENSYDNTSKFICDKFIRAAKPKKSVFPHFTTATNTENIKMVFRACMESVFKANSKATGLS
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MVKSPVVTGISPKEGPPGTRVTIRGEFLGNKATDLIGLTICGCDCLLSAEWKSDKKIIARTGAAKGKGDIIVTTRGGGTGTCTVQFRAYYETIGPMKESAVWIEESPMQSLAWGRRSLAPTGYTQEDPLGLSNEGNEKKFPEDLRDLFPDGSGDLSQENFTPGWFLLENHHATSFEDLKAGLSYLRRRVESQKEGQLSFLKSNAGSVIDQLDTLMTLRDRITQDNKVHGKEPVRQLDVTIRGSIDASHELFKDVLVRKEKADATRAALSAMSRHKFLFCLPNTVEKAAAKNEFDIVVNDYARVKNLFGKTEVPIFRKVLEEVDIKILAIRQQLHGKIREMPQGVEQQKKMIKALISLEAQQAGTSVAGKLKIDDPAWDAIEARAKHLEETFLKAYEQYSGKESHGSESKSRTDPAVTPVRVQFCEEMTEIAASQFPDLWRLGQAHFNGELRGASPPKPGNFKRIILTAIEQFCSYLRSALLATSSAHRSLVAAVSAVKGLPAWPSSSPSLNFLITWLPHCLRYVRVSYATLIRLDLPNEALDIVLKFIDELRLYCMSTILKKANERVKKLHEKEQWELSVTEFAGATSLPAKLQEILVEAIDDAQVACLTPEVREGPLLEPQSDGQRELSKRFQEILTSFCTVIETLALQRSDEDPQQAPMLSQLIGFPAALLQQQMSTGDKREWANPAITWEQRLLCCLSNCIYCNRIFFPKLGSLFTRHSFPVPTLAIENSRSTINGLFASLLEMYVEHKSDPLVGTIEPSMYLGRFQWDQVGPSEKLSPYAHECLDNLVSVYSEIFAISPSLLRPILEPIVQTVAEELARLMTCVQKFNVNGALQATVDINVIRDAVRVYSNETAKSFFVEALDAIPSVPESEQRTLETVKTIKNNIRLQIMCLQVVDP
The following text describes a protein:
Function:
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
Subcellular Localization:
Secreted.
Sequence:
YPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY
The following text describes a protein:
Function:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Sequence:
MSTVQSITASQKTVDGPSAKDWRGGRAASFNIIPISTGAAKAVGKVLPTLNGKLTGMAFRVPTVDVSVVDLTVRLEKAMIKEESEGNVKGILGYTEDDVVSTDFIGDTRSSIFDAKAGIALNDNFDKLVSWYDELGYRSMFGVVNPCVPYSRISTIKVMSEVCEARLAKSLFFIRIGDNEKALEHLKITETKTVAVGQKMDLVFYTLQHGFFGMDFDLISKSIDKAKSLFEEGGDWERKNRLKVYEGLYCISTRNFEKADTLFLDSISTTTYELFPYDTFIFYTVLTSIITLDRVSLKQKVVDAPEILTVIEKIPHLKEFLDSLYGCQYKSFFSAFAGMTEQIKLDRYLHPHFQYYMREIRTVIYS
The following text describes a protein:
Function:
May be a signaling adapter molecule involved in NGFR/p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm, cytosol. Note=Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.
Domain:
The nuclear export signal is required for export from the nucleus and the interactions with itself and NGFR/p75NTR; The histidine cluster (His cluster) and Cys-127 mediate zinc-binding.
Sequence:
MANIHQENEEMEQPLQNGQEDRPVGGGEGHQPAANNNNHNHNHNHNHNHNHNHHRRGQARRLAPNFRWAIPNRQMNDGLGGDGDDMEMFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP
The following text describes a protein:
Function:
Anti-terminator protein required to prevent early mRNA termination during transcription. Together with SCAF8, acts by suppressing the use of early, alternative poly(A) sites, thereby preventing the accumulation of non-functional truncated proteins. Mechanistically, associates with the phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit (POLR2A), and subsequently binds nascent RNA upstream of early polyadenylation sites to prevent premature mRNA transcript cleavage and polyadenylation. Independently of SCAF8, also acts as a suppressor of transcriptional readthrough.
Subcellular Localization:
Nucleus.
Sequence:
MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPGAENVTNNEGSPPPPVKVSSELPQAPTNSMPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDSAVMAQVQAITAQLKTAPTQPPEQKTAFDKKLLDRFDYDDEPEAVEDSKKEDAVAVATTALATAAPPVPAAATPAVAPAVPASSATSPPPPQAPFGYPGDGMQQPAYTQHQNVDQFQPRMMALQQDSMQHQVPLPPNGQMPGFGLLSAPPPFPPMPQPGMPQPGMPQPGMPQPGLSQPGLPQPGMPQPGMPQPGMPQPGMPQPGLPQPGLPQPGMPQPGMPQPGMPQPGMPQPGMPPTPPVQPTFQPTFQPQNEPHSQKPHQQEMEVEQPCVTEVKRHVPESRKSRSRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQIKSETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADFKQYWDVELGVTYIPWDKVKAEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAEASHTEPVSPIPKPVPVPVPALPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESADSAKMYGSAGPPAAPTSLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPMMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGSEDRDGRQQQPQQQQQQQQQQQQQQQQQQQQPPPQQSQTQQQPAPSQQPAPAQQQPQQFRNDNRQQFNSGRDQERFGRRSFGSRVENDRERYGSRSDERDNSNRERREWGRRSPERDRHRDLEERSRRSSGHRDRDRDSRDRESRREKEESRGKEKHEVADRAGGNKAVEAPLSQVGNTDTVSELNKGEAMATVVKPEESPAEATSSVEPEKDSGSAAEAPR