lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Inhibits the activity of serine/threonine-protein phosphatases flw/PP1beta9C and Pp1-87B. Required for germ line cell viability and differentiation, normal transcriptional activity and maintenance of DNA integrity.
Subcellular Localization:
Cytoplasm. Chromosome. Nucleus. Note=In primary spermatocytes and maturing spermatids, found throughout the cytoplasm with a distinctive concentration in speckles. In the embryo, primarily cytoplasmic with some protein in speckles in both the nucleus and cytoplasm. In salivary glands, predominantly cytoplasmic with a mild perinuclear accumulation. Also detected on salivary gland polytene chromosomes where it is associated with regions of active transcription.
Sequence:
MDRREDALLQALQTNASETERWEAFKRDNESTIRNLDKFAKNLSVEVMVPIGRKALMPGELIHTNELLVGHYEGYFSACSSHKAKEICQYRLKLAEEQLKKLAVENDLWQKKLHTPFAEGAVPSGDQVEIVEDFNEESHNKWLAEHRKRMRQQKQKERLEREAEPVKKDNEVLRKLEEREMMEELGLDPDNIDEDQLHDMLNQEPLKSTNESSPKSLTQEEEDELWKKLEAEEQNEADELSSEAEESLKTTDNLVRQLMSGETETPSSKKRTAGTNRNVEIQDPISEDDGDDDDEGDQEEEVRTIREQMSLLPNEDREPFLRAQLHVLKAKMRKIQKVNFISDELIHLMNVVVMLEDDLQDLVFEQELEASEEEEEVVENNHLPDEPSKELSTVSESSTNKRRISFALDDEKLEFRREETVAEMLPNAKKNSRDIIKLNAPLKPAGDPQPASIKTKRQTTQDILQKVERNIEFVKENQSVQDFDLLNRIMEESTGLINTLHISFTHSGAIPSPSSDQSDGIPGKPSDFYVRYEKDRARPNDSFPIYVNGFEGEEHVKVPIMSEAARGSAYEDPRSQFSKPNSSEICFTHSGSITPTSNDQSDDIPGNPFDFYEKYEKDRAKFSKSNSSEGDATDPESATKSILRNKSAVDLEPHNVNQQPKKGRKVRNQKKKERTLDDDLRDMSAYQKVMHDLVEKEPTAPEPLPPGKFIDSHAPKKRVSRFKEQRALNKT
The following text describes a protein:
Function:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
Subcellular Localization:
Nucleus.
Sequence:
MATEPKPVTEVAKMDLFEDDDEFEEFDMNEEWEDKEEGKEVAQQWEDDWDDDDVNDDFSLQLRRELENNTEKSSA
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that possess E3 ubiquitin ligase activity in vitro and mediates protein monoubiquitination. Triggers the monoubiquitination of phosphorylated BIK1 in response to pathogen-associated molecular pattern (PAMP) detection.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.
Sequence:
MTRPSRLLETAAPPPQPSEEMIAAESDMVVILSALLCALICVAGLAAVVRCAWLRRFTAGGDSPSPNKGLKKKALQSLPRSTFTAAESTSGAAAEEGDSTECAICLTDFADGEEIRVLPLCGHSFHVECIDKWLVSRSSCPSCRRILTPVRCDRCGHASTAEMKDQAHRHQHHQHSSTTIPTFLP
The following text describes a protein:
Function:
Vasotocin is an antidiuretic hormone.
Subcellular Localization:
Secreted.
Sequence:
MAEPSLPLSFLCLLALSSACYIQNCPRGGKRALGDTALRQCLPCGPGNRGRCFGPGICCGAELGCYLGTAETRRCAEEDYMPSPCQAGGQPCGSDGRCAANGVCCSADTCAMDAVCLEEGSEQAEEAAEKNLTVLDGAAGDLLLRLMHLANRQQQGKQPGL
The following text describes a protein:
Function:
Important modulator of glutamate signaling pathway.
Subcellular Localization:
Cell membrane. Synapse.
Sequence:
MAGQPLRRPAWVPLLLRLLLAGIAACDASPADDSAGPGGRGPRGRARGDAGADEAVPRHDSSYGTFASEFYDLRYLSEEGYPFPTAPPVDPFAKIKVEDCGRTKGCFRYGKPGCNAETCDYFLSYRMIGADVEFELSADTDGWVAVGFSSDKKMGGDDVMACVHDDNGRVRIQHFYNVGQWAKEVQRNPARDEEGVFENNRVTCRFKRPVNVPRDETIVDLHLSWYYLFAWGPAIQGAITRHDIDSPPASERVVSIYKYEDIFMPSAAYQTFSSPFCLLLIVALTFYLLMGTP
The following text describes a protein:
Function:
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
Sequence:
MYRIRVFGDPVLRKRAKPVTKFDENLKKTIERMIETMYHYDGVGLAAPQVGISQRFFVMDVGNGPVAVINPEILEIDPETEVAEEGCLSFPEIFVEIERSKRIKVKYQNTRGEYVEEELEGYAARVFQHEFDHLNGVLIIDRISPAKRLLLRKKLMDIARTVKR
The following text describes a protein:
Function:
May play a role in cilia formation and embryonic patterning.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSALKSLVPARFLTLTAHLVIIITIFWSRDNNIQSCLPLEFTEDQYRTEDTRLTVALSVTLALFVLELAGFLSGVSMFNSNQALLSLITHSSACVCLSFFVFHQWPCWTYWIIFSICSVFPAVVELFLLLSQRVL
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Sequence:
MITDVQLAIFSNVLGVFLFLLVVAYHYINANTGKPIPKAK
The following text describes a protein:
Function:
Enhancer-binding elongation factor that specifically binds enhancers in embryonic stem cells (ES cells), marks them, and is required for their future activation during stem cell specification. Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Does not only bind to enhancer regions of active genes, but also marks the enhancers that are in a poised or inactive state in ES cells and is required for establishing proper RNA polymerase II occupancy at developmentally regulated genes in a cohesin-dependent manner. Probably required for priming developmentally regulated genes for later recruitment of the super elongation complex (SEC), for transcriptional activation during differentiation. Required for recruitment of P-TEFb within SEC during differentiation. Probably preloaded on germ cell chromatin, suggesting that it may prime gene activation by marking enhancers as early as in the germ cells. Promoting epithelial-mesenchymal transition (EMT) (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MEGPQELLSGKLRLCFTPAARTSLLLLKLNDAALRALQECHRQQVRPVIAFQGNRGYLRLPGPHWSCLFSFIVSQCGQEGPGGPGLDLVCQCPGRSGPNRLHCLGPLRERLTIWAAMDSIPAPSSLQRHNRTEDARDRESWQNVGDYPEADTISQSQMGLEEVPDPLASSQGQSLPGSSREHMAQWEVRNQTLLPNRDPDQALPPSASQKHVDKKRPAPAAMVELKQKRLRTLAPSPLQGLPSQDLQEEDWEQEDKDEDMGPRLEHSPSVQADSESLSPEEVPDYLLQYRAIHSAEQQHAYEQDFETDYAEYRILHARVAAASQRFIELAAEMNNVQRGTPEHKALEEKIVQEYKKFRKRYPGYREEKRRCEYLHQKLSHIKGLILEFEEKNRGS
The following text describes a protein:
Function:
Riboflavin transporter involved in riboflavin (vitamin B2) uptake. Does not act in the transport of monocarboxylic acids across the plasma membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSSTHDSDKEEDSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDNQLSSESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKERLPHVIENSKDGESRWRYILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSDKFGRFNVAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIISIKTTADYQHYIIFCGLATFVSAVCYIISRAYCVGFKWVRF
The following text describes a protein:
Function:
Trifunctional protein with both thiamine biosynthetic and degradative activity. Within the thiamine biosynthesis pathway, catalyzes the phosphorylation of hydroxymethylpyrimidine (HMP) to hydroxymethylpyrimidine phosphate (HMP-P), as well as of HMP-P to HMP-PP. Also has thiaminase II activity and degrades thiamine using water as the nucleophile, resulting only in the formation of HMP (4-amino-2-methyl-5-hydroxymethylpyrimidine) and Thz (4-methyl-5-thiazole ethanol).
Miscellaneous:
MISCELLANEOUS: Present with 195 molecules/cell in log phase SD medium.
Sequence:
MTYSTVSINTPPPYLTLACNEKLPTVLSIAGTDPSGGAGIEADVKTITAHRCYAMTCITALNAQTPVKVYSINNTPKEVVFQTLESNLKDMKCNVIKTGMLTAAAIEVLHEKLLQLGENRPKLVVDPVLVATSGSSLAGKDIVSLITEKVAPFADILTPNIPECYKLLGEERKVNGLQDIFQIAKDLAKITKCSNILVKGGHIPWNDEKEKYITDVLFLGAEQKFIIFKGNFVNTTHTHGTGCTLASAIASNLARGYSLPQSVYGGIEYVQNAVAIGCDVTKETVKDNGPINHVYAVEIPLEKMLSDECFTASDVIPKKPLKSAADKIPGGNFYEYLINHPKVKPHWDSYINHEFVKKVADGTLERKKFQFFIEQDYAYLVDYARVHCIAGSKAPCLEDMEKELVIVGGVRTEMGQHEKRLKEVFGVKDPDYFQKIKRGPALRAYSRYFNDVSRRGNWQELVASLTPCLMGYGEALTKMKGKVTAPEGSVYHEWCETYASSWYREAMDEGEKLLNHILETYPPEQLDTLVTIYAEVCELETNFWTAALEYE
The following text describes a protein:
Function:
Forms stable clots in the presence of calcium.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
LQPGLEYQYRYSARV
The following text describes a protein:
Function:
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular Localization:
Cytoplasm.
Sequence:
MGDANITTSAWRLVEVGRVVLFNEGQYEGRLAVVVEIIDHKRVLVDGPSEKAPVARQEIALAKLSLTPIVIPKLPRASGVGHVAKKWEEHKVQEKFDESAWAKKRAAMQKRRGLNDFERFKVMKMRKQARYEVQKTFAKIRASAKA
The following text describes a protein:
Function:
May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1.
Sequence:
MAAETLNFGPEWLRALSSGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQEEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLPATSRGRGSTRSRGRGRGDSCFYQRSIEEGDGAFGRNPREIQRSQSWDDRGERRFEKPARRDGVRSGFEEGGAGPRKEHARSDSENWRSLREEQEDDGSWRLGAGPRRDGDRWRSTSPDGGPRSAGWREHGERRRKFDFDLRGERGGCGEEDGRVGGGNSHLRRCRGLDGFEDDKDGLPEWCLEDEDEEMGTFDASGAFLPLKKGPKEAIPEEQELDFRGLEEEEEEEEEPSEGVDEERPEAGGKEATPLPPPENSSSPSSLPALGPLWTTNEEGGEAVEKELPPAEGDELRGLSLSPRISSPPGPPGDLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSTAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVPFAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQHFLQLVGSRQLPQCTTLREKAAMGDLTPPQQQQLTTFLQQLQALKTPRGGDQNLLPTMSRSLSVPDSGPLWDLHTSASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQERREVELRAKREEEERKRREEKRRQQQQQQEEQKRRQEEEELFRRKQVRQQELLLKLLQQQQATNVPVPPAPSSPPPLWAGLAKQGLSMKTLLELQMESERQLHKQAAPREPLRAQAPNHRVQLGGLGSAPLNQWVSEAGPLWGGPDKSGGSSGGNLGLWEDTLKSGGSLARSLGLKSSRSSPSLSDSYSHLSGRPVRKKTEEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTAGSLDVPMAVAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQQQQQQQQQEAWLSSTSLQTAFQANHSTKLGPGEGSKAKRRALMLHSDPSILGYSLHGPSGEIESVDDY
The following text describes a protein:
Function:
Potential regulator protein for the acrAB genes.
Sequence:
MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE
The following text describes a protein:
Function:
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Sequence:
MSMCQERQCLDIYLRMLLAVNEKIADRELNRTNRELEQYAELKDQLRDQDMPLILSTCFNSVVFACEDGDVETAALALHVVAEYIDWVDINLTASPDAVQVYHRCLAEPSPMAEAACECIAAMALKGMPAAEKVQVFEALQVWPSLQQLAVQAMEVDDVDLLIKIGRALDCTAYATLQELQAATEPSLQHALMGLLMVVLPLAFAAYAHEDDDVSHAMLSSVTEYLALHKQAKEGQLPPEHDQLLQQLISITILKMKHEPEDLVVTDAQNEAEFEEFRKELKTVLANVCALNLNLVLDHVEDNILAVLQQAASAPWTELELVLYLIYCLAEYVPLPAKSETFEALPARIRMRNLVDHAIMAQVAADAHLGVLKQLFEVYGRAVRFLSPQSVDPLVSTMLGPLGIRHPDERIRSRCCYLLGMTVMKDRALRPYLGQYYPAFKASLAELLTFDMILNETLAPEDQLFLLEGLSWILSESSEAAATKAEDLGALVFPLLQAFQEVATRLLQSETSSEEHPILAARLSHIISSVTRLSKGFSAATLSACGGTTVFQQALDVFVTVLGTSIERSTLHGAVRMYLHRMVVALGSDVLTVMPIAIRGLLSEPTIEDLTEFVPLLAHMVVKFKAAVLPVLQQTLFPLVEALYGFLNAGQGENKSPEEAQQVLDVRRAHFSLLHSVVTHECAEALTVNPDAFPALMAPLDPHFNLGDVQFNLALGEIALLLLSLVRILGEPLLSHLQAQLLPSLGMSEAHALAVVQALHQELGNRSAAAAKSKLSATLRQADVIGITCQDLGWADCERDMESSKSETTEQKSHNEIDQIESDTGLQALPFHVAACTGGQFSQAHQIKNVESNDSTVYCSRLSRNVTFKLQVERLNHALVAVDICPPTLGYTCPVHSGLVFAATAEPNEFDYAWYELLCHCLVTIMFSFIVVVAFGWPIFTCGAW
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MLVVYYFYCFPFFSVNSRIFPMASDQNAAESIAKKLAQEEEWLQNFQKNIAKSAQIRQGIEQVVEKFDQRLSSLEKNVLPMHISNGKLQKKQHNIQRLINTIDATLQFYGKTSTVENAINSGNPSVDLDPYLENMESLQQAIIFFETHPNYRSQTDNMRITLDTGYTMLEKAYKNFLLKNSITVDPAPFVKNELTPRLSEIKIMTDEEPIIKIGVWLLKQPRVPNNFLGYYSEIRGAQILKNIKSIAEAQKSSQLASRSKLSTAVRKPVQRSEKVDVLIDLDACHAMCSALLSLLELEEKLMVKAIPDTSKRAQVFRELVSRPLAYAVVQTQKVVNEKDIGIVPLLPLLHLLSQNYARFHNLATNSIGDVQFDSLMRQLQVKCSSYVNEVIENLNEDTTKFVPPDGNVHPTTASTLNFLSSLTAHRVTVTQHVLALTAPQGSNTNLLLPKLFARILSALGSMLKKKANLYDDPTLATIFLLNNYNYIAKTLADEQDGLLPAITEMNSNILSFYHEEIATCTNEYLKSWNGIASILKSVDRIGEDKQMAKQIMSTFVRDFDQVLAQQMDYCISDPKISANVQTQVKSRIWKNYSQLLDTCQRLHVFPQGIKYTENTFEMAIRNLFSSARIN
The following text describes a protein:
Function:
Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.
Sequence:
MLDANLKTQLTAYLERVTRPIQIHASIDDIPKAREMLELLEDLVLLSDKISLDVHRDDNQRKPSFALTTPGQDISVRFAGLPMGHEFTSLVLALLQVGGHPSKATAELIEQVQHLDGDYQFETYFSLSCQNCPDVVQALNLAAVLNPRIKHVAIDGALFQDEVETRQIMSVPTVYLNGELFDQGRMTLEQIVAKLDTNAAKRDAAKIAAKDAFDVLVVGGGPAGSAAAVYAARKGIRTGVAAERFGGQVLDTMSIENFISVPETEGPKMAAALEQHVRQYDVDIMNLQRAEQLIPAGADGLVEIKLANGASLKSKTVILSTGARWRQMNVPGEDQYRNKGVAYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVAHVTLVEFDDKLRADEVLQRKLRSLHNVRIITSAQTTEVLGDGQKVTGLVYKDRTGGDTQHIDLEGVFVQIGLLPNTEFLRGTVELSPRGEIIVDDRGQTNVPGVFAAGDATTVPYKQIVIAMGEGSKAALSAFDYLIRSSAPVSADVAQAA
The following text describes a protein:
Function:
Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
Subcellular Localization:
Golgi apparatus, cis-Golgi network.
Sequence:
MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRRADRVPISFKVLPGDHEYPKCRSKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDIIASERAAALCNVCELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELSFEHAAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQHAKALCNHDAAVVYPSPDPLETPTGVLDFYGQRPWRQGILSFDLSDPEKEKAGILAIQLKERSVVHSEMIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEAWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDDQKSRIEKNLMNVLMNESPDPEPDCDALAVKTAQKLWADRVSLAGSNVFTIGVQDFVPFVQCKAKFHAPSFHVDVPVQFDVYLKADCPHPIRFSKLCVSFNNQGYNQFCVLEEASKASEVLENLTQGKMCLVPGKTRKLLFKFVAKTEDVGKKIEITSVDLFLGSESGRCVVLSWQGGGGDAASSQEALQAARSFKRRPKLPDDEVHWDSIIVQASTMIISRVPNISVHLRHEPPALMNEMYCLVVTVQSQEKSQIRDVKLTAGLKPGQDANLTQKTHVTLHGAELCDESYPALLTDIPVGDLNPGEQLEKTVYVRCGTVGSRMFLVYVSYLINTTVEGKGIMCKCHKDETVTIETVFPFDVAVRFVSTKFEHLERVYADIPFLLMTDILSASPWALTIVSSELQLAPSMAAMDHLESQIDKVVLQTGESASECFCLRCPSAGNLEGGVATGHYIISWKRSSGMENIPAISTIITLPHVIVENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTKQEMLYNFYPLMAGYQQLPSLNINLLRFPNFTNQLLRRFIPTSIFVKPQGRLLEDTSIAAA
The following text describes a protein:
Function:
This promotes the activity of RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MKISSPPGLRYPYTIQALHKRKDEDVKRSDKLFTCWYEETVTEEDRWGVEEQVKKKWQQHFDATTGGKIARWFVKPGTVVVRPGVELVEIEEPCTHETQFGGLCVDCGEDMTKVDYLTKERDVNRATVNLTHDNTALLVSHNEAVRAEEDTKKRLLNSKKLTLIVDLDQTVIHTTCERTVAEWQADPENPNYEAVKDVKGFQLADDNLSNVAANWYYVKMRPGLKEFFDKMSKLYEMHVYTMATRAYAQAIMKIIDPDRKYFGDRILSRDENYTDKLKNLTRLFYQNTAMVVIIDDRADVWQYSPHLVRVPVFNFFLGAGDINAAFLPKQQELVTQAKDKPPTPPNKVAQTETGLPAPVSVAGKPAEPAPTDATNGDLNDIGQQLLTMAAGEGGEVLEQQAKEQEKVIIAQQTERPLLQQQLMLDKEDAQAEDAEVFPEAPNGEMEHVEHPKARHSVLNDDDRGLEIIEKHLVQVHRTFYDEYVKAKAIPAGGRIAELKGEKSPKKRALSDIIPDVAEIMPRIKEEVLDGVVVVFSGIIPLGVDVQTSDYALWIRSFGAEVTTSVNRRTTHVIANPDRKTTKVKQAARYQHIKIVNPEWMFQCCTRWEHVDETPYSIEIDPAERGGSPFGELEDESINATGDEEPEEPAESPVELELTADNWASVDDELADFLNETDTDDDHESDSDSVRSDNSTASDAKQNKKKRKRAANSADVSEAEESDSSVASASKLQRRKKRTMERVTSLTNVLSADKSSGLPSPETTGPEEGQGDDEEKAPATNGVTPDLQEDYDDGLEAELLAGFGDSDDEHA
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Plays a role in sustaining courtship behavior in males, possibly through the reception of a stimulating arrestant pheromone.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGTRNRKLLFFLHYQRYLGLTNLDFSKSLHIYWLHGTWSSTAIQIVVVGVFMAALLGALAESLYYMETKSQTGNTFDNAVILTTSVTQLLANLWLRSQQKSQVNLLQRLSQVVELLQFEPYAVPQFRWLYRIWLLVCLIYGAMVTHFGINWLTTMQISRVLTLIGFVYRCVLANFQFTCYTGMVVILKKLLQVQVKQLEHLVSTTTISMAGVAGCLRTHDEILLLGQRELIAVYGGVILFLFIYQVMQCILIFYISNLEGFHSSNDLVLIFCWLAPMLFYLILPLVVNDIHNQANKTAKMLTKVPRTGTGLDRMIEKFLLKNLRQKPILTAYGFFALDKSTLFKLFTAIFTYMVILVQFKEMENSTKSINKF
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MTAESRWEATLEPREQEGFPLVKTEEEEGPWEAESSPHGSGRIFQQRFRQFRYQEASGPREALGRLRELCHLWLRPDRRTKEQILDLLVLEQFLLVLPEEIQAWVRLHRPESGEEAVAVVEEMQGEQNEPGQWFSEEKFVVPACGSRSEALEEDTEAPGASQESLATSPQPGSSPAQTEAGSLQPEMSLHLPKHDNPAETEGRESLSAKEGTFEKVGFQRPFRGRRQPNILTASAGGNTGEPEGRLESQRGRPARGRPRRAAPGGGDFKKVREAQKRPAAEKRSYECNECGKAFKWSSNLRAHERIHTGENLRRCDDCGKAFSARSTLIIHQRIHTGEKPYQCSECGKAFSQHSSLIYHERVHTGEKPYKCNECGKIFKISSNLRAHERIHTGEKPYECNECGKAFRNRSTLKTHLRIHSGDSCPAQRPAPAGAQGGFGGPPLFPVEPFEDRGQVPAVTGP
The following text describes a protein:
Function:
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Sequence:
MDTFCFFFTGAILILIAYIAWLRFGDFKRPKLSPGPAGCPILGYLPFLGRNHHAMFRDLARTYGPVVRISIGTVSIVAINDYQLIKSAFTNSAVQSRIRSLFLELTGFPGVGTLNGQAWRENRQLSMNILRNLGFGKTTLEEVIKDEVSRLTERLAAMNGKPIIARMEIVTSTSNVFTSLFFGTRHPHDHPTRAALNKLLLLADRVVCTGSLVVFLPNWMFEIAGLMPFTRIYCFKKAFGGLLGFIRKQVQKHEKMELSDRNQDYIDCYLEHAQQRLENPGSHIQSAYVPGNIQTFLGAGTNAIQRSLAWILVTCADKPSTVQAKIQQEIDRVVGQERQPIWEDRYQMPFTMATIWEMQRWRPILPLTLPRATDKDMELGGYVIPKGTIMLANIWAVNMNADLWDDPEKFRPERFIEQGGSKLRPKLDYFIPFSVGKRMCPGEALAPVEIFLFTTGILQKFTVLPEDGKTIDLTVDSGAFSSPKYQKLRFVPR
The following text describes a protein:
Function:
Orphan nuclear receptor.
Subcellular Localization:
Nucleus.
Sequence:
MGGPRFKDKVFLKCAICQESAEGFHFGAEACRACAAFFRRTVSNRKTYSCQGNNDCDVTINIRCMCRACRYIKCIEVGMNPAGVQQRLPPSKTLVEVSMDLPTVSNPSILSFPSPPSSLMLHIPSSYSNQMPILDKMRKSYETLCNARKTLHRKDGANIFQDNVPKPVTYKKAIDQGMKDVKLTSDWVSWCFEDFKNLSIDQKKILFHNAYTPYFMMEGGFLSHIRNTPEHLVMPSGDYIDTLDLNSFYNCSESDRQISSKEIDRLFKPSNDRFIKSVTLPMMSLQLDIFEFFVLFTLLLWDTGLIEISEECIEIGTKVKTQVLKELDFYMRNVKKVEEPLVRTANIVNLLPAVQKGVRRIQDDLEVTKVFDLYTASDEFYNLMSGRF
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MTPTASLLPAPPFVSISDARRLQLLPCGRCRPRLRCGGTEWGSVRTQMLSSFVGSRRSSRRSVICASLFGVGAPEALVIGVVALLVFGPKGLAEVARNLGKTLRAFQPTIRELQDVSREFRSTLEREIGIDEVPPSSNYRPTTTNINQQPAADPNAKPETAPYTSEELMKVTEEQIAASAAAAWNTQPASSQQQEAAPTTQSTDTATSGGNDGPAAPAPAPVAATESDASQAKQSEKADTER
The following text describes a protein:
Function:
Hydrolyzes certain amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA).
Sequence:
MHATSPKKLKVVLLQFLKAQHISYLQINTSAMAAFASAILFTVHLALAFPFRLSSAEAPPLLGAVVGEQQPLLEEARTPRFVTWLRGVRRRIHQRPELAFQEHRTSELVRAELDAIGVPYRWPVAQTGVVATIAGSAGPTVALRADMDALPVQEMVDWAYKSQESGKMHACGHDAHTTMLLGAAKLLQARKGDLKGAVKLVFQPSEEGYGGAYYVLQEGALDGVSAIFGLHVDPALPVGVVASRPGPFTATAGRFSATIRGKGGHAAVPHESVDPVVVAATAILSLQQIVAREVDPLHGAVVSITFVKGGEAFNVIPESVTFGGTMRSMTDEGLSYLMKRVKEIVEGHSSVHHCTASLDFMEEEMRPYPAVANDERMYAHARAVGESLLGENHVKVAPQVMGAEDFGFYARRMAGAFFTIGVGNESTMVTVQQPHSPYFVIDEDALPVGAAFHAAVAIDFLKKHS
The following text describes a protein:
Function:
Functions as a substrate recognition component for CUL4-DDB1 E3 ubiquitin-protein ligase complex, which mediates ubiquitination and proteasome-dependent degradation of nuclear proteins.
Subcellular Localization:
Nucleus.
Sequence:
MGPRNPSPDPLSESESEEEENTNYLNESSGEEWDSSEEEDPVVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDASTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLISPSRLSRDHATLNGALQFATKQLSRTLSRATPHAFLPKLVPLAFSS
The following text describes a protein:
Function:
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
Subcellular Localization:
Cytoplasm. Nucleus, Cajal body. Nucleus, nucleolus.
Sequence:
MSAREPRQMPSAIMTLGYCPHFEQFMDRTYNARNCEDQYRFPWKLLGSASFWYSSEYSEFVELSISRAFVTDWDLQKASGRSPEEELISPMEELKIRDGKGKKSIPNSALVPTSFGKRERAKHKSVKNDEYSIDCVQFDEYWERYGEYYINRTWLDILGKESPEDARTILLNKLSSMEIDPFLNREDVITSLSTLHDEEYSLSDEHWGRHVNEVKKGVRRLFELSKTKAAKKRCAAFIDAVCDILSSITQIILFQITGLGFVSDLEKKIKIDNNEERSENISDQALDEDVFYDVAYEFFDPHLSQKDATRIDSSERVHSESDPQTSSEPMTELSSIRFNFDPIRDKMLIGAEGRNMYPHDKSIKKYWFQRKRLFSRFDDGCLLDREGWYSVTPERIAEHIADRMVKREGSVILDAFAGIGGNSIQFALKGARVIAVDMDPIRLKCAKENARVYGVEDKIDFILGDFFSIASSWKDGNVTPRKVDAVFLSPPWGGPDYLTSEVFDIRKMTPDGVKIFDASYSISPNIAYFLPRNTKFEQLTTLCKSGKVEIEQASLNKKIKVITAYYGDLAQ
The following text describes a protein:
Function:
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.
Sequence:
MGNTTSSAISKEILEDLKLSTKFTETEICQWYENFQKQCPTGRITPEEFEEIYTRFFPEADAKGYARHVFRSFDTNDDGTLDFKEYIIALHMTSTGKTTRKLEWAFSLFDVDKNGYISKTEVKEICQAIFKLIPPEEQKKLPEDENTPEKRANKLWAFFDKKDNERLAEGEFIKGVIENETAMRLIHYEPLKH
The following text describes a protein:
Function:
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
Subcellular Localization:
Cytoplasm.
Sequence:
MRRAVIIPARLGSTRLKEKPLKNLLGKPLIRWVVEGLVKTGERVILATDSERVKEVVEDLCEVFLTPSDLPSGSDRVLYVVRDLDVDLIINYQGDEPFVYEEDIKLIFRELEKGERVVTLARKDKEAYERPEDVKVVLDREGYALYFSRSPIPYFRKNDTFYPLKHVGIYGFRKETLMEFGAMPPSKLEQIEGLEQLRLLENGIKIKVLITENYYHGVDTEEDLKIVEEKLKNL
The following text describes a protein:
Function:
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
Sequence:
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSKLDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYIKSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPEHSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSKIQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQNTENNQEKTFSSEESNSKPFMEENQNDEIVIKEDSYNPFVTKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNDGTTVQNYENKASDDYYDVNDIKGTKSKDPKRRIPYMEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIMLEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREAEDPFTCPHGRPIIINFSKYELEKLFKRVM