lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; sdhCDAB; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation.
Miscellaneous:
MISCELLANEOUS: The region encompassing approximately residues 42 to 181 has been shown to be periplasmic, however exactly which residues are periplasmic is not clear.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Domain:
The periplasmic domain is involved in C4-dicarboxylate binding and sensing. The structural disorder in the cytoplasmic PAS domain has an important role in signal transduction to the kinase domain and may be the decisive structural feature that characterizes the activated kinase.
Sequence:
MRHSLPYRMLRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQISDMTRDGLANKALAVARTLADSPEIRQGLQKKPQESGIQAIAEAVRKRNDLLFIVVTDMQSLRYSHPEAQRIGQPFKGDDILKALNGEENVAINRGFLAQALRVFTPIYDENHKQIGVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEISTLFEQRQAMLQSIKEGVVAVDDRGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQVVDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAISTFRDKTEVRKLMQRLDGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKIKSPVIAGFLISKINRATDLGHTLILNSESQLPDSGSEDQVATLITTLGNLIENALEALGPEPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSERGVGLALVKQQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR
The following text describes a protein:
Function:
Flagellar protein involved in sperm flagellum axoneme organization and function (By similarity). Involved in the regulation of the beating frequency of motile cilia on the epithelial cells of the respiratory tract (By similarity).
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, cilium axoneme.
Sequence:
MAQGRERDEGPHSAGGASLSVRWVQGFPKQNVHFVNDNTICYPCGNYVIFINIETKKKTVLQCSNGIVGVMATNIPCEVVAFSDRKLKPLIYVYSFPGLTRRTKLKGNILLDYTLLSFSYCGTYLASYSSLPEFELALWNWESSIILCKKSQPGMDVNQMSFNPMNWRQLCLSSPSTVSVWTIERSNQEHCFRARSVKLPLEDGSFFNETDVVFPQSLPKDLIYGPVLPLSAIAGLVGKEAETFRPKDDLYPLLHPTMHCWTPTSDLYIGCEEGHLLMINGDTLQVTVLNKIEEESPLDRRNFISPVTLVYQKEGVLASGIDGFVYSFIIKDRSYMIEDFLEIERPVEHMTFSPNYTVLLIQTDKGSVYIYTFGKEPTLNKVLDACDGKFQAIDFITPGTQYFMTLTYSGEICVWWLEDCACVSKIYLNTLATVLACCPSSLSAAVGTEDGSVYFISVYDKESPQVVHKAFLSESSVQHVVYDQQGIFLLVGTAEGKVFIINANSSSSFQIIGFTEVAKDILQISTVSLLETDIVEVMVLSSLPEAGRSRLEMFTLPTLLPQVSTTFADERGRLKDEIIHKYLYELEHALSSAVLGFQSNQIYGFCSQVPYICSYLLPEEEHTGIYILKPYKKVQSRQYGPGLLYLSSHGLWLITIAKCGILCIRDVYTLETFAWCRSHSHQGHGIQSMRISMDGQNILVNGRDDGTLVYLKWKRFGGHLASEILDYYQKLLISLSSAMDKENHYLSTTPKVSVDLGSDSEHTKQKASTDLSQDELVLTDVKKEIPWIQQKSQEAIKKEVNLFSKKRKEIKQGIKSLSKTILNMMEENDKLENIAKLDQQEFGLDLEELERLHDESQEEVAKMIKDVEMHNLAKSYLAELIKEECWNSMAVKGRALKCFHIPCVVENFPMKARTVEELKELERVLQQKKIEAECLKLRKEIVEAQSGVKLIKQRHEEDDEEEEEEDKTVKYSNLPNYLLGSLSTDFGVDTSLLSSQLELHSREEKINQIILLKDIIYKVKTVFNNEFDAAYKQKEFEIARVKERNVRIREIILDLELEEAVWQPEFEDCEKPERTLVVQDEEITAHKHIKPWHKAKELIVNHEKEHWLLIQDASTRLRALMDMMGGVLEVKKEDILRMVIPQPAFMAKPDAVWTEEERKQFKDYEKKVKELNEERDKYRKSLEAELKKLQNSIQESTQAFDEHLKRLFERRVKAEMVTNQEELKISNLAFSLLLDEELSSREKFLNNYLTRKQHEKSQTSEAVRKSREDLDVCKEHYDNLLAEDKVMDRSFKKEFSEIPGHQVDILYKLFKRRPRISKQKTHSETTSVVPFGELPGSGKLNKDAFAQLMKAMDELDNISNMPEGLDPLVWNHFCMTRRAKVENEQKVKQKAADLLEMATFLQKRVEEEEKVQQEIERVFHELILLQEEKVRFQLNLTIQILLKQGQVELENFQLVLEYSDAILINKNIIEDLNSVIRTQGQKKVASMMESKDVHKRILQIEWEHKKMEMEREDLNQKAWDIQMLFFSRDRQKYLNEPNYEALISIQIGIMEQTIAVLDKMHKKNVENCKKLLKKLGKFSNQKDIANYALSCNLREELVAVSERKDICNAMGSKLTCEKIVKERYENMMQQQKLTNISKQQAEQISILQTEVERLRMKTFPALVQM
The following text describes a protein:
Function:
Transcription factor required for iron homeostasis and resistance to oxidative stress. With AFT1, activates the gene expression in response to low-iron conditions, also called iron regulon. Recognizes the consensus iron-responsive element (Fe-RE) sequence 5'-CACCC-3' in the promoters of target genes. The transcription activation by AFT1 and AFT2 depends on the mitochondrial iron-sulfur protein biosynthesis pathway. In high iron condition, the presence of iron leads to dimerization, which in turn leads to a decrease in DNA affinity.
Subcellular Localization:
Nucleus.
Domain:
The CDC motif is involved in iron-sensong via binding to Fe(2+) or [2Fe-2S] cluster, which leads to dimerization and loss of DNA-binding.
Sequence:
MKAKSMKSIISVPISVSKTGKMKLTASPDNLASMMSKDQNKLIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVRSKVGLNPKSKGSSSRSHACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPLVTPIISCDCGLTKEIEAFNNIFLPLSNPPLTSKKNLLKTNKNSVSKIKSRQMDNSKPRPRLKTKLDADLHDTGFLDNFKTRNSCVKIEKEDSLTNLNEIDFTNMFCNDNFIQNYNQGLMELLTEPTPGPSSSSCILPSTPTRPLSQSKMDIALSESTTSSPNFMETDAPYGDEIIKVSKDTKSNAPTADTDIATNLGKERNENFGMLNYNYEALLHFNDEHFNELNSIDPALISKY
The following text describes a protein:
Function:
Virulence regulator that has both architectural and regulatory roles. Impacts cell wall functions and pathogenesis through regulation of multiple genes, including the espACD operon, which is a key ESX-1 component. Influences target gene expression positively or negatively, depending on its binding position relative to the genes it controls. Acts by binding directly to the DNA. May play a central role in regulating virulence gene expression.
Subcellular Localization:
Cytoplasm, nucleoid.
Domain:
The N-terminal domain binds DNA and the C-terminal domain is involved in dimerization. Both domains are required for transcriptional activity and for ESX-1 function.
Sequence:
MSTTFAARLNRLFDTVYPPGRGPHTSAEVIAALKAEGITMSAPYLSQLRSGNRTNPSGATMAALANFFRIKAAYFTDDEYYEKLDKELQWLCTMRDDGVRRIAQRAHGLPSAAQQKVLDRIDELRRAEGIDA
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
Subcellular Localization:
Cytoplasm.
Sequence:
MTETTITTSDNVEKYGEREIRDAQLITFPNPRPGRRYDVHITLPEFTCKCPFSGYPDFATLYLTYCPDQKVVELKSIKLYINSYRDRHIPHEEVTNQILDDFVAVANPLYARLKADFNPRGNVHTVIEVEYHQEKAS
The following text describes a protein:
Function:
Produces the terminal flavan-3-ol monomers required for the formation of proanthocyanidins or condensed tannins in leaves and flowers, as well as in the skin and seeds of developing berries. Behaves as a reductase and as a C-3 epimerase. Catalyzes the double reduction of anthocyanidins, producing a mixture of (2S,3S)- and (2S,3R)-flavan-3-ols (Ref.1). The enzyme catalyzes sequential hydride transfers to C-2 and C-4, respectively and epimerization at C-3 is achieved by tautomerization that occurs between the two hydride transfers. Converts cyanidin, pelargonidin and delphinidin into catechin and epicatechin, afzelechin and epiafzelechin, and gallocatechin and epigallocatechin respectively.
Miscellaneous:
MISCELLANEOUS: Hyperbolic binding of NADPH and NADP(+) to the free enzyme, with a single binding site each. The most likely enzymatic mechanism is sequential ordered Bi-Uni-Uni-Bi, with NADPH binding first and NADP(+) released last; MISCELLANEOUS: This enzyme is strictly pro-S stereospecific and the reaction mechanism involves two hydride transfers from two distinct NADPH molecules.
Sequence:
MATQHPIGKKTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGDLKIFRADLTDELSFEAPIAGCDFVFHVATPVHFASEDPENDMIKPAIQGVVNVMKACTRAKSVKRVILTSSAAAVTINQLDGTGLVVDEKNWTDIEFLTSAKPPTWGYPASKTLAEKAAWKFAEENNIDLITVIPTLMAGSSLTSDVPSSIGLAMSLITGNEFLINGMKGMQMLSGSVSIAHVEDVCRAHIFVAEKESASGRYICCAANTSVPELAKFLSKRYPQYKVPTDFGDFPPKSKLIISSEKLVKEGFSFKYGIEEIYDESVEYFKAKGLLQN
The following text describes a protein:
Function:
Modulates immune responses.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MAALCLLLLLSLAEAIDLRVPELPVIGLLDKDVILPCWFTPSEGFTPKNLSVFWKLPNQQQDYGFVLGEDLQENQSPQYKDRISLFHEELSKGNMSVLLQQVRLTDEGIYTCFVNVQNSSSASVSLQVGAPFTKPTLHLEPSEALKPGDQVTVTCHTYDGYPEANILWQNGEGQNMTENITTSQVANEKGLFHVQSSLSVILETSDTYTCLVFNPVLQDVTHASLTVTGQHLSFPPLVLWVTVGLSICLLCLLVALACVCRKHLKQTCEEEQENAGNEEHEENGELKTAMQPLKVTSPGEDDDAECLE
The following text describes a protein:
Function:
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity).
Miscellaneous:
MISCELLANEOUS: Coordinated expression with SEPTIN2 and SEPTIN7.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cleavage furrow. Midbody. Cell projection, cilium, flagellum. Note=In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle. Found in the sperm annulus (By similarity).
Sequence:
MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPATHTQPGVQLRSNTYDLQESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHTYHDSRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELTKFKIKITSELVNNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMKARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEKKN
The following text describes a protein:
Function:
Component of several N-terminal acetyltransferase complexes. Inhibits the N-terminal acetylation activity of the N-terminal acetyltransferase NAA10-NAA15 complex (also called the NatA complex). Has chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT in neuronal cells probably while associated with the NatA complex. May play a role in the NatA complex-mediated N-terminal acetylation of PCNP.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MATEGDVELELETETSGPERPPEKPRKHDSGAADLERVTDYAEEKEIQSSNLETAMSVIGDRRSREQKAKQEREKELAKVTIKKEDLELIMTEMEISRAAAERSLREHMGNVVEALIALTN
The following text describes a protein:
Function:
May act as a carbohydrate transporter.
Sequence:
MEVWRRETVSSTLLLVLTCTILFLMSGVSATRFIVGANMGWTSNVNYTEWAKGKHFYLGDWLFFVYDRNQMNVLEVNKTNYETCNENHPIHNWTTGAGRDVVPLNVTKTYYFISGKGFCYGGMKVAVHVEKLPPPPASLPEKSKNGSPSNYGSQIVLPAVFAIVALFWDNFIGFWY
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MSVYXQTRKNNLKCHKKRLTQDQVRLLEISFNSNNKLDSNRKSQLAQELGLPPRQVAIWYQNKRARWKSQSLEVDYKALQQRLDNAMLDNERLKLEVERLKEELNKAQEMLLAFNTTTNNYSSISSSCDEVGSSCLQLHDQSKHHLDKELYACLIGDEGHFGHNFFASSMS
The following text describes a protein:
Function:
Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTDLLAPSKTNYQNFNDVGRDTSHTKGDNNSTPKMKDNPAKPRQRHGDAAKTKVKKEDKLPLQELIANLEENELASTIEQVRQTFPSNSLIWLNELVGYVQMHLSRAENSYDAIFTGKSKDFPMNLLSNKFKQLAIQLLEKCPEAVISIFFEDCIDNMLKNIRNNIQTYGYRIMIQIMTRYNPAIVLNKISTYKPSVLEIVPYEALSILWAFNQASIGDVAVGYQVWFELMFPAMNVRSLAPYAITVIEDLFKSKKSKNINKIPNVGPKEFVTLLHMLFSDNSSLHASSRKKLISLYPKLKGDYSLLITDTINHFISINTAIISKKRNKAEDVAEFQSEVKAFVDNAAYEKKPNASMTGSYLLYLLILLFLFGLGTLHAIISYPQYFNLDESQVESLRTHTRFLSTRLLNYMRILSDLASVAVEKLWLLTKAGFKYTTDVLSPYQLLIKDYIPTVLDAIKKCLDHLLVVFTNILAKSIPSSDLDLTNLRSYQPVVDT
The following text describes a protein:
Function:
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
Sequence:
MRIIVVDNYEEMSKKAAAMVASQVILKPDSVLGLATGDTPIGMYKEIINIYKNQKMDFSKARTFNLDEYYGLNRENPQSYYYYMMNNLFNHVNIDKNNINIPNGMADNIEIECKEYERKIDKAGGIDLQILGIGVNGHIGFNEPNISFESETHLVNLNEKTIESNSRFFSSKEEVPTKAISVGIKSIIHSKKIILLACGSAKSDAVSKTINGKINPNIPASILQLHRDVVVIIDKEAASKLNLK
The following text describes a protein:
Function:
Intracellular mono-ADP-ribosyltransferase that plays a role in different processes, such as protein translation and unfolded protein response (UPR), through the mono-ADP-ribosylation of proteins involved in those processes. Acts as an inhibitor of protein translation by catalyzing mono-ADP-ribosylation of ribosomal subunits, such as RPL14 and RPS6, thereby inhibiting polysome assembly and mRNA loading. Mono-ADP-ribosylation of ribosomal subunits is promoted by NMNAT2. Involved in the unfolded protein response (UPR) by ADP-ribosylating and activating EIF2AK3 and ERN1, two important UPR effectors. May also mediate mono-ADP-ribosylation of karyopherin KPNB1 a nuclear import factor. May not modify proteins on arginine or cysteine residues compared to other mono-ADP-ribosyltransferases.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MDIVSCDFLYSLCVSAALNYKRDSLLRPFPPFFVNEDQEKAFDDLIKTATKLPALHKIQWNNTDHINPKSIRLLKWVINPKTFHLTLADNKEFQKFTELTADIDPPHAPDYLFKVVYNDKKSEKFQQLAEEHSLMYAYHGSRVENFHSILHNGLRNNLNKVTLFGEGIYLSSSFKVSAPFSPTGTAWSNSFFGDSISCVALCELVNHPDVKCSVEAVKEDSKDSSKHRSYIKGSEGGQIPDKYFVVRNDELVRVKYIALFAPKADKKLISNVLSGKTVTPTERRGFFARHQFFLLMISYIFILFLIGFFNSSVFTAWWRNRAHHEE
The following text describes a protein:
Function:
Cleaves proteins C-terminally to the most C-terminal basic residue. Can process the alpha-mating factor precursor. Required for cell wall integrity.
Miscellaneous:
MISCELLANEOUS: Present with 538 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Note=GPI-anchored plasma membrane protein (GPI-PMP).
Sequence:
MKLSVLTFVVDALLVCSSIVDAGVTDFPSLPSNEVYVKMNFQKKYGSSFENALDDTKGRTRLMTRDDDYELVELTNQNSFYSVELDIGTPPQKVTVLVDTGSSDLWVTGSDNPYCSTKKKDTTGSSFKQVNKDALASVVESVFTEISYDTTIVTSEATATFDSTASTSQLIDCATYGTFNTSKSSTFNSNNTEFSIAYGDTTFASGTWGHDQLSLNDLNITGLSFAVANETNSTVGVLGIGLPGLESTYSGVSLSSVQKSYTYNNFPMVLKNSGVIKSTAYSLFANDSDSKHGTILFGAVDHGKYAGDLYTIPIINTLQHRGYKDPIQFQVTLQGLGTSKGDKEDNLTTLTTTKIPVLLDSGTTISYMPTELVKMLADQVGATYSSAYGYYIMDCIKEMEEESSIIFDFGGFYLSNWLSDFQLVTDSRSNICILGIAPQSDPTIILGDNFLANTYVVYDLDNMEISMAQANFSDDGEYIEIIESAVPSALKAPGYSSTWSTYESIVSGGNMFSTAANSSISYFASTSHSATSSSSSKGQKTQTSTTALSISKSTSSTSSTGMLSPTSSSSTRKENGGHNLNPPFFARFITAIFHHI
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MLEVVLQVLSISAITTTIALFFCGIPICMQIRRQGAVGDISGVPFLMGVLGGSFWLRYGLLKMDYVMIIVNVVGVACMAFYCVFFLIYSLPKKTFTCQLILVTSTIGGMVLWIALKPNLDYLGVICMTFNIMNFGAPLAGLGVVLKNREVSTLPLPMCVANFLVSSQWCLYGNLVSDIYIIIPNGIGMFLAIVQLALFVVLPIRENEKSPLEKLASWFTGRDSKVKDLERGDCIVSSPPSSPQKVPNETRSDVEDKFDKLMAETSSTIPSDSRRGSMGSPPSYKSRSSSDPDLSSIQSP
The following text describes a protein:
Function:
Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MEEFLSTLRDHDASSVLSSCEPELQELMRQIDIMMGHKRHEWEAEVRAMELSLHNTQEELQSAKALLDKRNSEIRVLGKQLEELHTGKQELVVKYEEQLLHVKEELSKLKRSYEKLQRKHLKESRDGALSREEDRTELSRLNSKIEEFRQRSAEWEQQRLQYQRQVSLLEEQRKTLAEQFSLIQSQGVGRPQEQGQGELQRLRSQLQRAQDSLHAQELELERLRLLQDELGDSIKEQQVSCHAAAHRRGQVLSEEREELKATLDAQDQFVRSTGVQQQQLRREVNRLNQTLQAKEQVIRSLEECLSSPGSAPNLASLRQDLEKVTARLNSSQTCESHLKAEVMRLRDKLESMRKYKAEMSRREHEWKQMEEEHSRCTAENKRLRDELERAEQTRCGEQEGMRKEVFQLTSELHQRDITIATLTGSTSSIERQLRAEVERAERRASELKVTQVQLETLKLENQHLNDLLERVESQSPKRGDGELASLRDSYVSSLKSLEEENRQLRLEMTELRARMEASNQTWQDKYERALLQNQNKNHLYNEQNRADEDVQRRHQEELQAMETQMQERASHYEEQIQTLLTQLENLSRTSPYRPDGQTQESKTSVSPARSSASSASSSSSTRKAQRVATLLSAVANGEEAQASSSDSTGSPNTSVTTRFLEEETLRSQELLQRLDAHIQSMKLENSNTVCKYLGKTGNPQNDVFWQGTHSFCKMID
The following text describes a protein:
Function:
In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.
Subcellular Localization:
Dynein axonemal particle.
Sequence:
MVMGFFLWTRKNSGINSQKTRFPDRRLCAFFSVQLNTLCAPFPMASEGQNEEKETLPELAIAPFQWGAILSAVKDQIPSMDSDIYASDGDEDEELFIFQRDQSNLIPDFSEELEDLPLEEADLQKTFAFMRHLTEIQDEEQGSVPTDSNYFGFLNEERPSQQVRDASEFPTNEPESGKDAQKDKDVPSPSSNPLPSMETAPPFEILNSDMKERRKLIETKILSKAALGRPTRDDTQSSPSDPLPSMETAPPSVITNNDIKEPKKRTETKIPSKATSGRLTGDVGPSQSRNNNNNFERIAKAERELGVISAEHPRELTLLAFEEIEKWDLDKVLQDLEKQSDKTSWKGEPAFPSMYYENSRATSEAKLMGKLEELSLEQSRTFFAHRRKCLAKLPHFSECQGDGRNVPVLAPLTSGRGLGSMELEWAPEPPTVYIDLRDTVSPKPELLSDAEESFSNSSTDEEEEEEEDVDLTGQENVEGQECLQPSRKNCTGKSFLLQQLRNFRRTVSHSAPDKGRSPDLISSGEARQPNVRGKCHLKWRGLASMDPADPKADTLGNMKNVPRPSRKPKEETEEGLCSRLSQDPSAEYPRK
The following text describes a protein:
Function:
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.
Subcellular Localization:
Secreted, cell wall. Secreted, extracellular space, apoplast.
Sequence:
MGQARAHLLASLWAFYLILAISMVTGDLTNDLDILWGNSKVFYDNSGKQTISLTLDRWTTSAFRSKSTYLFSRIDMDIKLVAGDSAGTVTTLYVSGQGMNRLLILVDDKLIRQIKNNLMYSVPYPTYQPMRVYGSIWNADDWATMGGRVKTDWSQAPFTAYFRNYRAIACPPQQSSPLCGQSSGNWFNQELDVTRKQQLQEVDANYKIYDYCTDTKRFKDNLPKECTIN
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MGVSTVGFRTQKYNPAESSEVMYARFRQILSDLNNAENVNKVSREIISKIERNARQIQFNSTRHLKDRVGDITLWKNQLCEEIKETALEIIQLNEFKTRLEKAQLAHEIINMIVSDNLNAREHRDGVDKVQDNVELGLLKELEITNSAMELLKRTLKQCEEQIKRNKNCKHEMEMDWSDKKEAHDNDCFNASLKEDSRCKQFYPAAAKFQEIQSTPESWAQFTHDNLAKAEQERMSSIQLRCLIDNLLDTTANDIRKQADDVNFLFNNRIKVLSETLWKLNEDLTKVNKMVYNCELNIETIKRSIKNYEELMKVAQTRLRNRENRPNVELTRDPAQYSLVSEVNELARSLDALIQKTNESESALKDMLDERTLLEKNKLVVEYSIFIDREKCLPHRTRYPSKMKLLGYQ
The following text describes a protein:
Function:
Exonuclease that digests recessed strands of DNA duplexes in the 3' to 5' direction but hardly single-stranded DNA or blunt-ended duplexes. Also able to digest 3'-protruding strands and 3'-recessed strand termini of duplexes containing mismatched bases.
Miscellaneous:
MISCELLANEOUS: Helix-distorting lesions (apurinic sites and cholesterol adducts) and oxidative DNA damage (such as 8-oxoadenine and 8-oxoguanine) block the exonuclease activity, while other DNA modifications such as uracil, hypoxanthine or ethenoadenine have no effects.
Subcellular Localization:
Nucleus.
Sequence:
MSSSNWIDDAFTEEELLAIDAIEASYNFSRSSSSSSSAAPTVQATTSVHGHEEDPNQIPNNIRRQLPRSITSSTSYKRFPLSRCRARNFPAMRFGGRILYSKTATEVDKRAMQLIKVLDTKRDESGIAFVGLDIEWRPSFRKGVLPGKVATVQICVDSNYCDVMHIFHSGIPQSLQHLIEDSTLVKVGIGIDGDSVKLFHDYGVSIKDVEDLSDLANQKIGGDKKWGLASLTETLVCKELLKPNRIRLGNWEFYPLSKQQLQYAATDAYASWHLYKVLKDLPDAVSGS
The following text describes a protein:
Function:
Cell wall formation.
Subcellular Localization:
Cytoplasm.
Sequence:
MEFCVLFGGASFEHEISIVSAIALKGVLKDRIKYFIFLDENHHFYLIEESNMHSKYFAQIKEKKLPPLILTHNGLLKNSFLGAKIIELPLVINLVHGGDGEDGKLASLLEFYRIAFIGPRIEASVLSYNKYLTKLYAKDLGVKTLDHVLLNEKNRANALDLMNFNFPFIIKPNNAGSSLGVNVVKEEKELVYALDGAFEYSKEVLIEPFIQGVKEYNLAGCKIKKDFCFSYVEEPNKQEFLDFKQKYLDFSRNKAPKANLSNALEEQLKENFKKLYNDLFDGAIIRCDFFVIKNEVYLNEINPIPGSLANYLFDDFKTTLENLAQSLPKTPKIQIKNSYLLQIQKNK
The following text describes a protein:
Function:
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDLTRAPITVAWLLGTLFIMYLQVIKLASPLDLYFDFNLMMKNQEYYRLITSLLYFGPAVPATLFSLLSFANFASLIEVDLFGRKPAEFVVFLLYVSISSILSSVFTREVFFGPIITLTCLYYWTKHHGNMSMQIMGLPINIKAAYAPFAYTAMNYYRQGFWGMIPNVIGIVLGHLYFYFHDVTNVRFGKKFIGAPKWLNQAFEYVEKLFV
The following text describes a protein:
Function:
Iron-storage protein, whose ferroxidase center binds Fe(2+), oxidizes it using dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the BFR protein shell.
Sequence:
MSKTQTIENLQKALAMELTATHQYQLHACVLDDWGMGLLASKMREELQEELGHSEDFLNRILFLKGNPNLTMQKTPVQAKSLKEMFESDLADEKEAIDFYTTASIQASEDRDIGTRQLFERIAVDEEGHAGWLELQLDLLERMGEPAYIAKHMPANSDE
The following text describes a protein:
Function:
Catalyzes the hydrolysis of fatty acid esters with a preference for long chain fatty acids (C16-C18).
Subcellular Localization:
Secreted.
Sequence:
MPKPALRRVMTATVAAVGTLALGLTDATAHAAPAQATPTLDYVALGDSYSAGSGVLPVDPANLLCLRSTANYPHVIADTTGARLTDVTCGAAQTADFTRAQYPGVAPQLDALGTGTDLVTLTIGGNDNSTFINAITACGTAGVLSGGKGSPCKDRHGTSFDDEIEANTYPALKEALLGVRARAPHARVAALGYPWITPATADPSCFLKLPLAAGDVPYLRAIQAHLNDAVRRAAEETGATYVDFSGVSDGHDACEAPGTRWIEPLLFGHSLVPVHPNALGERRMAEHTMDVLGLD
The following text describes a protein:
Function:
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Sequence:
MAQTFVNSKIQSGKVVVFIKPTCPYCKRTPELLNQLPFKQGLLEFVSITANSDTNEIQDYLQQLTGARTVPRVFVGKECIGGCTDLVNIHERGELLTRIKQIEALQ
The following text describes a protein:
Function:
As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenesis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
Subcellular Localization:
Membrane; Single-pass membrane protein. Nucleus inner membrane.
Sequence:
MPKEQQELLKKESQTLENNFREILFLIEQIDLLKALLRDMKDGVHNHSWPAQREAVQDQATAEVLDEEMSNLVHYVLKKFRGDQIQLADYALKSAGASVIEAGTSESYKNNKAKLYWHGIGFLNYEMPPDMILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYGVTKKCEGEEMFLGQFIYKKMEATIQTFELQNEASESLLCVKLQILSNWGHPKYTCLYRFRVHGIPSDHT
The following text describes a protein:
Function:
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Chemoreceptor for inorganic phosphate, which is required for taxis at low concentrations of phosphate. Is also responsible for the positive chemotaxis toward 4-chloroaniline (4CA) and catechol. Does not recognize inorganic phosphate directly, but via a complex between the periplasmic protein PstS and inorganic phosphate.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MRLKQLTNLNTLLLLTVCLALGITLWWSQRAMERPFQLLDQYLELSQRFDEQVARNIRQYLGSGDAVRQQAALQALESLAEALPELPPDLARTLAPSLAELREFSAGDLLAAGKLAGDPQGLLLQAERDLTGNLEQWSAYLDAAAGQPQAGAYRTPLLLASLHLTRLSLARAKLVESANPALAGDVERELANLREQAGRIEALPLLGVLDEQRSASDDFAAMMGLAGDAEAGAGNAEDRGVALRRELASLLQRYPDELRRTRDLIERRQQLSADTGARLDAVRQALATLEPQVRGERQRLQGQVRLIQGGMIALILLIALAIDSLQRRLARVLGQLVPALSAWADGDFSRPISLRTRTEDLRNLEDSLNRLRSFLAELVGAIHRRAEQVAGSSQTLAEVSSGLHAGVERQAGDTGQIRDALGDMEAAIQQVAGDASQTADASRSAGQAVEHGQRVIGESLGGLRELVDEVQGNAQSIERLAEESATIGSVLTVIRSIAEQTNLLALNAAIEAARAGDQGRGFAVVAEEVRSLAQRTAGATEEIQQLIGRLQQAARQSVEAMRSQVEHAERTAEQAGAAEGALDEVVAAIHTIGVMAERIAEGSTQQSQAVGEIRSHSERIHALGGENLRLIGHSREQGEQLRQLGGDLRTTVQAFRL
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
Subcellular Localization:
Nucleus.
Sequence:
MDGNGMNIRNWGFFEPPATVLKGHLGLQLMSSMDEKPLFGNIHDHHHHHHHHHNHQTHQPHHPTVMESTNGGAFHHHRVCGISETPMPIEYMRDSWVNHKDYRDKYLNVLSGNHHYLTGYGFLPETSSAQSMQIHEQPNLVKVEPDPQLEEVCQERDIGGLAKKRGAGKSQLLKSPKSKKAKKATRVPKVEATPSVPRARAPRKSAEVVINGITMDISVFPIPVCSCTGAAQQCYRWGCGGWQSACCTTNLS