lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the hydrolysis of glucose from the disaccharide unit linked to hydroxylysine residues of collagen and collagen-like proteins.
Sequence:
MKFLTIYIVCTSVLAVSVVQSFKMPSFDEITDLFSSLYSSDKSSGSKSSKKSSKHKRLKRQSAEIGDESLEPFEVRSSALPLMADKATINKRYMPTLGNGYIGTTVYSDKMYLNGLFNGAGSQSHRAAIPALLMSRINLSNPEIERRGTRKYVYNALQGYFMETIKSEYAYIEHKIYLHQKYIRLYVVEINYKLQPVNFGGGFLTLSYPPLVSEDIDFKKPVPYIGNWLLSGTTKTAEKGASPRTVFVFYQQPLPMISISGSQKSANYTFIMSVDTNEANARAEFDKAQLDLLNGDDANYNFFMSHVNEWQKTWDGGRIELSGSNTNQLIKAVWFAQAYILNSLPAENPYLPPPYSDLFYGCGRTSIGKGELGKDYQGHVMWDNEFYILPAILPFHPYMAKQMLRYRSAMGKAASERAASKGFRGYHYPWESAYTGNDVTSDPCPGNDTDCNWRKFYTTSGVALAIRYYISMTRDRDFMINPIYSGCDMSREVTWFLASQLVFNEGLKRYELLDATGPDDYHPRVKNNAFLLCSFSLAIHFARYLSCMCQRNEREEVPDEFVRKAFYLNLPYDKIKRLHYQYEGFDPDRDKPLKMADAILLNHPLNWNYSTDIMRNDLNYYELLTEQKTSSMTLSWFVIGWKWTGEVQKMATAFLKSYQDYIIQPFKIWTENTERSEADQAVGSTNFLPGMGAFLQSLIYGFAGVRIKPDRLEFCRPMPPPNHKKMVLRNFHYLNNNLTFTIENNKVTLEVLAVDNRFPLLLRVNRTDAPEVPLTANSKPIVIEQALDGFFIYSFQETCELPRDYIYMPFGYIPWADEYNINGVPSLHTFSFIFLAFVTNFYLTFFL
The following text describes a protein:
Function:
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Sequence:
MIFRLGDFRFPDDPARLYPDTPDRPWVLEIGFGDGRFWPHYARTFPEPPNYLGVEISGVSLLKAHRRLKDAGLTNAVLTKLPAEVLVAQVIPHGSLDAIIVNFPDPWPKAGHEDHRLLRVPFFQVAASRLKPGGAALLTTDHDEYFEFACAQAEASGVMRVERVGPPPAALETKYAQKWRDLGLGVNHARFVPTRHDPVPNGTFAPYSEEDPAVPHAVLTLPADFSPQHFDKLTVRGKTWTVVLLDLYATLRRGGWVALAHVVEGDLTQEVLVGITEREDGTHLVRLAKFGGPIITPGVKAAVGAVTEWLEGQGAVVKHRGY
The following text describes a protein:
Function:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.
Sequence:
MKVSLGNGDMGVSAHLQPCKAGTTRFFTSNTHSSVVLQGFDQLRIEGLLCDVTLVPGDGDEIFPVHRAMMASASDYFKAMFTGGMKEQDLMCIKLHGVNKVGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLDNCVEVGRIANTYNLIEVDKYVNNFILKNFPALLSTGEFLKLPFERLAFVLSSNSLKHCTELELFKAACRWLRLEDPRMECAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSDRTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDERAQEWRSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRSAAGELATVECYNPRMNEWSYVAKMCEPHYGHAGTVYGGLMYISGGITHDTFQNELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSPTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEENPGSPSRESPLSAPSDHS
The following text describes a protein:
Function:
Binds to the host entry receptor YueB and triggers viral DNA ejection. Binding to Yueb. This interaction initiates a cascade of conformational changes at the gp21 C-terminus causing disassembly of the tail spike organization and opening of the cap region formed by the N-terminus of gp21.
Subcellular Localization:
Virion.
Domain:
The N-terminus is part of the distal tail cap. The C-terminus is part of the spike structure and is probably involved in host receptor binding.
Sequence:
MRSLSKNIWIMSNFEVLLTTLTGDRDAGGCRYWNGSFEEPLSPGETATYQFYADASHPNSKYVINDNKVIFKEPEQFGGDYRMFTIIDTELGRSEQDGRYIIATCEPAWYELDDDFIENKRPTDKTPQEALDLLLEGTRYEGEVDPDLQMRASDSFYQVSVKEAVIQFFQTWGGYFKDTIEFDGNEITRRVIKSLKRRGAANGVRFEHDKDITSIRRNITGYPKTALYPYGASLEMTDEDGNATGGYTRYIDIKDVVWSKAAGDPVDKPAGQAWIGDPDLLKVFGRPMPDGSLRHRWTRWQNEDITTPEELIEAAYYDLINNVSKAIVNYNVEVAPKNVKLGDTCIILDREFATPIELEADVIKMTYFTDRPEEGATIELGEYLNLDDIERQIGAINDRFKKNEGKWNTGGGITEVTDGAFPDKKPPKPSNITVKSMFQSIFLSWNYDPSSYIAGYRVYASKTPGFTPTDNDIIFEGKMSGYEHKVGNNETWYYRLSTVNYHKTESDMSDQYSAQSERIMNDDILFGAITADKLANLAVTADKISRSFDEGNIFPGSLLKPSQFYDYPNTKHSVTDKTFNELTITQVIDDSTRLRFGISGQNKAPNNIQRMPLEQGQIYTLSFEVKRNNTTDLSYIHLKKPDNTFMLLSSSLKDISAYPSDEFVRVDLQFTAPETSSKFTLGFGGYNRNGNVTPCSFVIRKVQVRKGTEIKDYGYSPYDIMLVDGAIYSDYIQSAAINSAHIADAAIGSAAIQNAAIKNAHLGTAIVDTANIKDAAITSAKIKELSADLITSGTINAINITGSLIRGGRFEPLNESSAYTSYIEGDKIYQRVNTINYGGTPKKTYNDLTITSGGVTMVYGGRDTGTDEPLREMTLRDGSLYMSGNKNDTGYSEIQMYCNDDDVVNAPKSIFRQKLGGVNRMSLHSYYNSVPGSYNVQMDTRNTSIYSHFANGWQLTADGKIMIMSKNGQGIYLDPSNDNVAGQVTMHVGNAGQAGGLIQPVIAGAPHYSITDIHGALQTNMSVMLYQYNFVMPSKGDAYASKYNDIPPPFECENIFMVVPTVFGGYSDHVHATITSQSSSGFRCYVRGTGSSTGILGRTFQVRFLIFYEVN
The following text describes a protein:
Function:
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MATNNTTIDQILLPVESNGSYILDMKELQREMTRPLLTALLMAFAYSIIFLVCLVGNLIVCVMILKSKRTTSATDYFIFNLAICDLLVGIFCIPFTFVSHVFPVLSLGPFACKFIPLAQGVAVGASVFTLMAIAYDRYRLVIHPSQNKAPVKYWSCILAGVWVSAISIMVPQAVVREEISHMLPGGDIKVCLEFWPSYTQRQAYSAALLACCYLGPLVISACLYLMVAVTLRRRKITNNTMHASQRFNKVTKMLVIVIVLFTLSWIPLYTCWMVEDFGKLTGSKKLILHDYVYPFAHWLAFSNSCVNPLLYGYFNKSLRKRFRDSLVRKSDNEITGGNISLKIKASVNRKAILKYRRNSNK
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MSGGRVLHRRSPAPLVLALAWAMLFVALSDAQLEVGFYDYTCPRAEQLVRTVVHAAIRRDPGIGAGLVRLFFHDCFVRGCDASVLLDAVPGSDDAVEKASQANSPSLRGYGVIERAKRVVERRCRRRHRGLRRARRQRPPGGHRVRGAGGAARRPRLQRVGGAQQPAPALLQRLAVRRQLRRQGPQCRRHGHALGRALLRPHPLLSHRLPALPAGRSRHERHLRQVPPGAVPGRDGAPGPGGAPGPGHGAPARQPVLQERADARGAVHVGRDAPDAGRHGGARRPLRAQQDCVDVAVRGRDGEDGRPRRAHRHPRRDQEPLQQS
The following text describes a protein:
Function:
Required for DNA repair. Binds to DDB1 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair (Probable). May function as the substrate recognition module for a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MGPTTRARFVHNRRRRRRRGPYAAPDDDDEEEDQQEASSSSSSSDEGEEDAEEEGSGEVDDDDGEAAEPSGKEEEVSPVAAAARSGRKASITISLKKVCKVCKSTGHEAGFKGAVYIDCPRKPCFLCKMPGGHTTLTCPHRVAMEHGVIPASRRNTNTSLDYVFQSQVKGKIPMVKPQFLIPNQLECGNIKFHQRRVTCLEFHPTKNNVLLSGDKKGLLGVWDYVKLHEKITYDSVHSCILNSMKFDTTNDGLLYTASSDGTISSTDLDTGIGSSLLNLNPNGWNGPSTWRMIYGMDFNSDKGLLLVADSFGFLHLLDRRLKARIGDPILIHKKGSKVTSLHCNPAQPEVLLSSGNDHYARIWDTRKLEPNSAFVSLAHGRVVNSGYFSPQSGNKILTTCQDNRIRVWDYIFGNLESPSREIVHSHDFNRHLTPFKAEWDPKDHTETVAVIGRYISENYNGIALHPIDFIDTSTGKLLAEVMDPDITTISPVNKLHPRDDILASGSSRSIFIWKPKTESDATEERNREKAKEFVYGSGSRKKSNGKHENSSDDDSDGSCDGKKKKKAKKTRFTHTIKGKGKSKV
The following text describes a protein:
Function:
Binds human IgE in vitro, and may neutralize IgE antibodies present in blood from repeatedly tick-bitten people. Does not have antimicrobial activity against E.coli or M.luteus.
Subcellular Localization:
Secreted.
Sequence:
MFRYLVFLLIVGAVSCQRRKAVYKPCGGSGKLISVEVEPCDSDPCVFKKGTDVKVHVTMVADQDSDTATLDARVKVFGFQMPVPGIETDLCKGTVECPVIKGRKYSVTAIFPVPSLMSLKTEVTFKVIGDKGLSVCGQSDIVIE
The following text describes a protein:
Function:
An adapter protein which plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Together with FGR, it acts as a negative regulator of natural killer cell-activating receptors and inhibits interferon-gamma production. Acts as a positive regulator of both T-cell receptor and natural killer T (NKT) cell receptor signaling in CD4-positive NKT cells. Together with MAP4K1, it enhances CD3-triggered activation of T-cells and subsequent IL2 production. May be involved in tumor necrosis factor induced cell death by promoting reactive oxidative species generation, and MLKL oligomerization, ultimately leading to necrosis. Involved in phosphorylation of LAT. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal proline-rich region interacts with the SH3 domain of PLCG1; The SH2 domain is important for restoration of BCR-induced calcium response and JNK2 activation in BLNK-deficient DT40 cells expressing LAT.
Sequence:
MTSQGNKRTTKEGFGDLRFQNVSLLKNRSWPSLSSAKGRCRAVLEPLPDHRRNLAGVPGGEKCNSNNDYEDPEFQLLKAWPSMKILPARPIQESEYADTRYFQDTMEAPLLLPPKASVSTERQTRDVRMTHLEEVDKPTFKDVRSQRFKGFKYTKINKTPLPPPRPAITLPKKYQPLPPAPPEESSAYFAPKPTFPEVQRGPRQRSAKDFSRVLGAEEESHHQTKPESSCPSSNQNTQKSPPAIASSSYMPGKHSIQARDHTGSMQHCPAQRCQAAASHSPRMLPYENTNSEKPDPTKPDEKDVWQNEWYIGEYSRQAVEDVLMKENKDGTFLVRDCSTKSKAEPYVLVVFYGNKVYNVKIRFLESNQQFALGTGLRGNEMFDSVEDIIEHYTYFPILLIDGKDKAARRKQCYLTQPLPLARLLLTQYSSQALHE
The following text describes a protein:
Function:
May be involved in cell adhesion processes, particularly in the central nervous system.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MVYPGPPGLIAGLLLAALSLSCVDGAKALGFVGHGYNLTVSQGHEAKLNCSLQGIEEPEIQWLKDGVPVQSADQMYIPVDEDHWISFLSLKNVERPDAGKYWCEAEHSGRKSVSDAIWIMVEGVPYFTLEPKDLSVTPNSPFNMTCAAVGPPEPLVIIWWVGDSPLGKSESSPSVLQMSGIHERTAFSCEAHNAKGVSSSRTAIVEVKGLPYPPFNVTISKVTGSTATVTWFPGFNSFSLIKSCTIQVQSLHGNREMYSRLISAPPFAVLLDELQPLTNHSVRVQCTNEMGASPFTEWRTFHTKETVPQLLPQNVHMTKTETSLLLDWEEVEPDREGYNILGFKVQWEQENATQGELFVQENQANLTKWNPEKDLTIRICIANAAGCGPWSEFLLAGSKEEAGKQRHPHTRMSWVPMVLGILTALVTVVAMTLIFLRKGRKETRFGNMLGSMLGRGGPVIQFTAARSFNRRGPEMMEATLDSIGISEELKSKLKDVLIQQQQFTLGRTLGKGEFGSVREAQLKMEDDTMQKVAVKMLKAEIFCSSDIEEFLREAAFMKEFDHPNVCKLIGVSLRSRTKGRLPVPMVILPFMKHGDLHTFLLMSRIGEEPITLPVQTLVRFMIDICSGMEYLSSKNFIHRDLATRNCMLNEDMTVCVADFGLSKKIYSGDYYRQGCASKLPVKWLALESLADNVYTVHSDVWAFGVTLWEIATLGQTPYAGVENSEIYSYLIAGNRLKQPLDCLDELYEMMCQCWITEPKRRPSFVDLKQRLEAIWGRLSILSASQDQLYVNLGETCGAAAAVSGLHSAFCSEEDYCAGPSQTCGTSAITSDYRYIVNPGCLREGNEWSSSAQNGEARGLLHEEEEEEEEEMQEEQVVITL
The following text describes a protein:
Function:
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (By similarity). TFIID recognizes and binds promoters via its subunit tbp-1, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (By similarity). The TFIID complex consists of tbp-1 and TBP-associated factors (TAFs), including taf-5 (By similarity). Essential for early embryonic development, but not required for transcription of some genes; probably acts via activating transcription initiation by RNA Pol II, as part of the TFIID complex.
Subcellular Localization:
Nucleus.
Sequence:
MDSENSSSHSISSPQMFQNTHNNSAMEDNLLSRPMNNESLQMIIGYLRRNGLTETEELLTREAGPVLRVEGSNGLPPEEAISVEFDTFVQHANDCTDVVQAEFSQLLFPIFAHSYIALIEKHAATARIFFNRFKIFIPECFSEFVYQLSLIEDAMTLRANEHVHILRENKFLVRLSRPTLKHLESIQTRVIGVKNIIAKHICIENADEVSTNRTTIETQMGGILGVTSKSDKRHKMMFSVLKDELMQNIEKRKTKGKDWKDMGKKMQTHCPQADRIPLPPISEHLREERRNWLRDVGKMAIISAESPVSICMYTTVNAPIGVASCDFTDDSSLIAMGLSDSSIVMNAMDPMNKMKKLRDMEFLDKIDIETADNVQSQMFDLQGSTTSVRYTGHGGPVFSVNFSPDRRLLISSAGDRTVRLWSMETQRNAVIYRTPAVVWQAQFCSRGYYFATASADKTAAMWSTDRMHPLRIFADPYGDVGCIDYHPNCNYIAGGSDDRYVRVWDVCSGTRVRIFSGHKASIIAVKFSPCGRYIVSLDAIGNLMIWDLAYQRLVAAEITEQAGTKGSITFSRDGGVFAVSHGNSSIQLYSLDTLIGTVLAAGQNDSYIEPKVNLDGFNIGSYATKETAVIGLHFTRRNLLLGFGCFGQ
The following text describes a protein:
Function:
Involved in cell migration and signal transduction. Important in several developmental processes including epidermal development, Q neuroblast migrations and muscle arm targeting. Required with ina-1/pat-3 to stabilize the commissural axons growth cone along a precise direction and are required for the cell to respond appropriately when signaling in the growth cone must change. During gonad morphogenesis, involved in distal tip cell (DTC) migration from the dorsal side of the hermaphrodite body to the midbody to allow for formation of gonad arms.
Sequence:
MSSSGLDEIDLNSLRDPAGIFELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKEQPHEQTIRHSIKEHIDRNRRVKKDDADYEYSGSEDDEPSPNNRGPSMGIRDDSESSSMIPMDNTLRKGFQKLQESSRGFAEPGAQQLRRLPQQPAPAPFQYQQSRYVEPRRESSEVKLRAVSSRGAADGPRHSPASRPRPVSHHQRSPQQSHPAAPHLADLANYEKRRRSEREERRERERQAHHAMPIARVSASVPAPQQSRKMSEPLLITHVKPEDLDVLASELSKMGGHHNGRSREESMSPPPPAPPPREASISSITDTIDVGELDNGADAEWDDLKDIMMNGEGTLRGPNKPLPPTPTDGENTLVSDVRRNGNGNSGHGAYKGKKIPEIRPGIISLDDDDSDSDNEEGNEPLMFKPINASSSRGALPDLLPKSPQLRRQINDQTRQMSDDRADESASLFGSFYQPNGFQNSDSRSSIQHSFSNRDREKSFVGYFGGGAGAGGGTVNRPGRPQDINQVQVNVTPNSNGTPAENDAPEIRKYKKKFSGEILCAALWGVNLLIGTDSGLMLLDRSGQGKVYPLISRRRFDQMTVLEGQNILATISGRKRRIRVYYLSWLRQKILRTEGAGSANTTEKRNGWVNVGDLQGAIHFKIVRYERIKFLVVGLESSIEIYAWAPKPYHKFMSFKSFGSLSHVPLIVDLTVEDNARLKVLYGSTGGFHAIDLDSAAVYDIYTPAQSGQTTTPHCIVVLPNSNGMQLLLCYDNEGVYVNTYGRMTKNVVLQWGEMPSSVAYISTGQIMGWGNKAIEIRSVDTGHLDGVFMHKKAQKLKFLCERNDKVFFSSAKGGGSCQIYFMTLNKPGLTNW
The following text describes a protein:
Function:
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
Subcellular Localization:
Cytoplasm.
Sequence:
MDPKEKEKMAEELNVEETKDTAEEQPQDDQAEEAAPLTHEEQLEKELEDAQAVIEEQKDKYLRLSAEFDNYRKRTMKEKAELILNGGEKSISSILPVIDDFERAIKTMETAKDVKAVKEGVELIYNKFMAVMAQNGVKVIETKDQPLDTDYHEAIAVIPAPSEEQKGKILDCVQTGYTLNDKVIRHAKVVVGE
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Subcellular Localization:
Cytoplasm. Cytoplasm, perinuclear region. Midbody, Midbody ring.
Sequence:
MSNKKQKEEINTAGGSVILKTMVRDKDKEQKEEKREKKEKKRLEKKEAENVKKEKKKEKKELKKIGKAGRSGSITSDSSTHSGAQEFDSYGNDSNGGGGGLSASIDSNGLSSSGQPMQTRHLEKEVGEKQGIYSLSSQDRSSSLPHSSQDDQAKPLITESEIFSSESFLIAVSDTDHLGPAIKSVFENNKEKEVIKILNAYIAQKDLDIEKICGENHEGFINSVTAFLGLKGENLDLKQDVINLNYELQEIGRKYVTKAEELFAYKQIKDNIKRTKEVLNNCQYAILLGMKVDEYVQQKKYYQAIKNMDQLHNVYLKKLSDFQFARNMDYNIPVLKEKIKKLVKDEFNQWMVEIKEKSAVIGKLGMIQTSKKLLKEREINPLKIKTTFGENEQIWDKILDIPPIINSSSIGSLALYPTLNSPVTAPIYSPNSGKTPSSFGFNKQINEKDLKEDINQFSPFDESDIQFHPLYQCLFIHASIGQLEEFQAYYTLNRLLQFQLVIQPKESGQVWELFLQQILGYFMVESKVIDSTEPFLSKTTINDSWNSALVKVTSVLQELFTHCVDTQPLIAFKKFVLIFTNTMSFYSYHVQPLYYFLDTMKEKYCQFSIKEAVERFTIILERDSHCSLIIESLEEYKSLILANKLDILERQQLRQLQNSLNNNQFQFGDKNLNNNNNNDDDDDYFDEDENEDDKISKRLPKSFLFSKMVPQFYTLIKKFISEFYEFSDQLTENENFIIRSTDTLIKKINEVLYSYLTQSQAVPQVIQLVINLQHLISGCSFFKDYLNSLILGEDYQKNQSIVNETNKVILNSQNLLYTTKSHGEKLIIKLCEQKIEDLMSSAANIEWFPQNAIDDRPRDYIIDVCTFLEVTLPFISPLSQNLKEEFITKAFKNISESLFSLIYDDQLKKLNLQGVKSFDADLKYIETYVKEKANEKERTTTTSRNMVGYFVELRQLTNFLLSDNPEDFVDPKIKAKHYNLITNIPQLLNILNKYKEESKGFTTSKEIKDRNKKIADAIKKIKDSL
The following text describes a protein:
Function:
Activates the G-protein coupled receptor TrissinR in vitro, leading to increased intracellular calcium ion levels.
Subcellular Localization:
Secreted.
Sequence:
MTKTTMHWLAHFQIILLCIWLMCPPSSQAIKCDTCGKECASACGTKHFRTCCFNYLRKRSDPDALRQSSNRRLIDFILLQGRALFTQELRERRHNGTLMDLGLNTYYP
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MAPQPLEQGGAVTSFIPTGQEMAQRQNLIPLGRLIDFIIQRTYHELTVLAELLPRKTDMDRKIEIYNFSASTRQLFIRLLALVKWANSASKVDKSAKIMGFLDKQSMLFIDTADMLSRVARETLVHARLPNFHIPAAVEILTTGSYSRLPSVIRDRIVPPDPITPAEKRQTLQRLNQVIQHRLVTGSLLPQLRKFRIENGRVTFKVDHEFEVSLTVMGDAPTVPWRLLDIDFLVEDKETGDGKALVHPLQVNYIHQLIQGRIVDCTDALAEVYTCLHYFCQSLQLEVLYTQTLRLIRDRLDDHIHVDEYVVGSRLTVSYWRELTNKDPKSELGYRLTIQTDPNDAAKQLAILHVPSIGNKEADIADRAVRSDLLSMERLLVHTVYVRSLARLNDVKTELQLFLKDVEYNIQGTPAMLTVPVLNPCLRAEHIYITVDTHTGMLRCHVPKHLDCPIMPEMQHALNNDWSKLQHLISELRYWITQRRCEKTLQHLPAATQDRLPLIYSHTHPIARMGPHKVFIQLYRHANVILIVELKEKKTCPNEMTYTFYLVLVKPSSVEEGQSPDVLSGQPPQPSAAGGPAPGSDSANAAMPKMYLRVLSMIEFDTFVATHGPGTYIDDPSPTSTSGTSVKRKVSPLDNALSAIGPPLKQQKTIYPAYFIPELAHVVAMCDEKLPFVTLAKEFSMRKIPHGGLQVEANATSLVLKLLTLPQPKPPQAPPTPQQQQQQQQQQQQPGTSDAKSSGAGASANEPKTVHVPPIDKQVWNALLKRLLSVSVRAQVNKSNQTRLWTMELVFYGSPLPSLHHKEQGMRRAVYLQYEMQPVESVSKVVDQLLSDWSKIVYLYTLVHEFREQYNNEKYNLPSMVAIKSYSYTNLLLAYGPNKDVSVNICWDTEAKEFRLVFTGGNSAINAHSMMRDQLQAHLNHNYSLAQVVHMLHETYQPLSSIAKLPIIPHLAILQSPKIPVLSFCIIPQSPTLLRISFQGVYCLEVRFRGGGLCTIRDGAYSRFDRSHVVEEFTPTQGLKGFLSKYVDETAVFRRRSQSEDDNPPSPVTLEDPSAGAGNNGGGGGGGGGAGGGANTFLSGGTGMRGPQSPRDPGLRFAAPLTPPTSSNPHTPASPHPIGGGGGAGGAGGQGGQGGQGGQQQSHMNNFNMTSPPASHMPHPSPGGGLMPSSPLNAQPSPMAAHSPGPSSLSYMQSHTDGSPFAALSPAASNWPGSPGMPRPSPRPGQSPEHKVQTSHHYTSRVLPARSWAGAIPTTLTYEALDTLCRATPHPQKEVPGPELSPLERFLGSVFMRRQLQRIIHQEESLMAITSNEPGVVVFKADCLQYQVFLNPNHMQSLHLKVDQLPMGPMMDGKPPYQWAAQDLQILEQFFDHRVAAPPYRPAVMTSFTRMLNLPAKVLKDFIQIMRLDLMPELVQGNKWNVQFVLRVPPSATPIVPVGTTTILSHRQKILFFIQITRVPYLPNMEWKDAVTMLLPMVYDMNMNHTTLAERREPMPPQLTSAVSAHLRRFSECSVLLPDECSLFPAVHDLLLTLTLPNEPPAPGQMQMQLGGVMQPGGGPGVPGGPGGPMGGQIGGPTPQVVPQVGSSPSPMMHSPMQQMGGGGPQPGAYGGMVGGPGGGPQSGGPVGGGPGGPN
The following text describes a protein:
Function:
Component of the 40S ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MFCNFVTKRLEHAASEPPAAVSTRARPQASPGPRPPAAGRPAGTAEATPGGAGPGGGRGTPARKRRGAAHAPSFPAPAPDAAAAEMLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRRSRPETGRPRPKGLEGERPARLTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ
The following text describes a protein:
Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSRRYDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGEKKVTSKLLQTSTYSEKMYKIDDHLVQSLCDTKQGYTQFGGLRPFGVSFLFAGWDKNHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSLLKQDYKEDATREEAVELALKVLSKTMDSTSLTSEKLELAEVFLTPSGTVKYHVHSPDSLTKLLLKHGVTQPAAESS
The following text describes a protein:
Function:
Catalyzes the stereoinversion of LL-2,6-diaminopimelate (L,L-DAP) to meso-diaminopimelate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
Subcellular Localization:
Cytoplasm.
Sequence:
MSALANHAFAKMNGIGNEIVVVDMRDSTAKVTPDDARAVASAQGGVPYDQLMVLQKPRLDGTEAFISIYNNDGSEAGACGNGMRCVVRRIFEKTGQATATFETAAGLLNAWQGPAPDLYTVDMGVPKFGWQDIPLAEEFRDTRYIELQIGPIDNPILHSPSVVSMGNPHAIFWVDDVNAYDLARFGPLLENHPIFPERANITLAHIVDRDHITIRTWERGAGLTRACGSAACATAVAAARLKRAERNVEITLPGGKLGIEWRERDDHVLMTGTATFEYEGNFDPALFAPAG
The following text describes a protein:
Function:
Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes; Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus.
Sequence:
MDVLGENEALQQFFEESGHDVTGVLESPVVDTSMLEQYLSNDLDPSTFMLPESPPDSGSEPCSPPQIPGKMCALVLHGRIRMADRSTPAPGLHDADKQLCQAQCPSSSHPLPPRTLTSLSGHSLPLCATQTSVFPEPKKRKHSDSVEGGVDSHPWNDPSRPKRPIMNAEPSGEAPSYDGDGQNGGSCPGAYQSLTWDVYQSNQWTALYSSSYKSLPAPGYHVDTDKGFNYSATDEAFVCQKKNHFQVTVHIGMAGNPTYVKTPQGVKPIENFYVKVFGIKVEAQNHVITIEQSQSDRSKKPFLPVKVSLPEDKITKVTLGRLHFSETTANNMRKKGKPNPDQRYFMLVVGLYASVEEEQYLLVAHVSEQIIVRASNPGQFENDSELLWQRGNTPDAVACHGRVGINTDSPDEALVVCGNMKVMGTVMHPSDRRAKQNIQEVDSTEQLKRIAQMRIVEYDYKPEFALQMGIDQTHETGIIAQEVKELLPSAVKEVGNVTCADGEKIPNFLWVDKEQIFMENVGAVKQLCKLTDNLENRIQELEVWNRQLAKLKRMGSLTSTLSAKSAHRKVSKNCSIPPSPKPSPIASAKKCLSEKYEHCSRNKFFQATIIALVSTMAFCVISITALYMLTLNDDYNASPGNSNDSLLSTPASTTTFPSSFSPPASTSSTTQPTMTPSPQPPDVDFCSLMYCEVVYCCPSGPNIMLNSSSLIERLSHGHPMLLPEMGVYLADNCILESSNDKDWKNTTIKSLFIKENQQIIDQQYCVKDHCGSGNYTYVIPISKYMHEDMRVTLQMNTTEALVIYLCKSSKGTDCMGLQEENSPENLLSNTQLPQGYEHIWPLPVAHLHWSSYHFRVVVAGQANCNTDPNYVGVLFTDYHVYFYRRCT
The following text describes a protein:
Function:
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
Subcellular Localization:
Cytoplasm.
Sequence:
MDSLLFEKLLVIEEDKIDEDFFCNICNNIMYKNYQCTNGHIYCVSCTEEIKSKNAGCPECRVELGSISVNRYLERQINKLQIFCPNKFYNTKDYIADEEYGCGFECSIDQMESHTKECEFSFVKCPQNGECELVRKNLLDEHIKECNSERVECELCKASVLRVNLKKHYQSECLQYTVACRCGSKVKRESLPLHYANECANEMVDCIYGKLNKGCKGKVQRSEMDKHLLSSNHHQTIVNSFVSLREELELERKKLNQCHTKFQGQWRVENWNSKFCSQPKGYVLKLNFSIGNRPLCLQLYPNGQTNDNKNCSLYLYNYYDLPISCNFTFEIVAGKDGIKKDSVSSVINSKNGKGWEDFIPAAKKEAFGNTLVINFRVKITSVVHQYFNK
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide. Its role in saliva is unknown.
Subcellular Localization:
Secreted.
Sequence:
MRALVSVVSLFFLGIQAHSDWSYSGDDGVGESQWSEQYPSCGGERQSPIDVKTEEVMFNPSLKPLSLVNYEKENLEFTMTNNGHTVSIDLPPSMYLETSDGTEFISKAFHFHWGGRDWELSGSEHTIDGIRSIMEAHFVHFNKEYGTYENAKDQKNGLAVLAVLFKIDEYAENTYYSDIISALKNIEKPGETTTLKDTTIRNLLPKDVHHYYTYPGSLTTPPCTENVQWFVLRDKVTLSKAQVVTIENSVMDHNNNTIQNGYRSTQPNNHRVVEANFLNVQDMYSSYHLYLKNMQKEILQPKKQKKTKKNRHFWSRK
The following text describes a protein:
Function:
Plays a key role in innate immunity by acting as a pattern recognition receptor for beta-1,3-glucan from fungi and lipopolysaccharide from Gram-negative bacteria. Upon recognition of invading microorganism-derived products, acts upstream of protease spz processing enzyme SPE to activate the Toll pathway and to induce the expression of antimicrobial peptides drosomycin, cecropin and attacin.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Note=Secreted and attached to the membrane by a GPI-anchor.
Sequence:
MPGLCIGILLLIGFGCTTAYKIPTPTVELLETGFSVSIPDEEGVKVVAFNVNRNRNFTSFINEGQYNVRLTEPQNGRWTTNFSSVPLRSQDVLYLWTSVQHQKAVYQDLAQPLPVCNLGGEYRPRGCSPGDDDFTDDNQLSTEDSALEPTAPSVCEPSESQVSPQIGVSICKGQLLFEETFDQLNESLWIHDVRLPLDSKDAEFVLYDGKAKVHDGNLVIEPLLWSSYRPDLSIANSRLDLSERCTGTHNRIKECILHSTGSGPSGIMPPIVTPRISTKETFAFQYGRIEIRAKLPKGDWIVPLLLLEPLTEWYGQSGYESGQLRVALARGNSVLRMPRGKLVDGRSLYGGPVLSTDAHQREDLWLSKRKISHFGDDFHTYSLDWSSNRLLFSVDGQVYGEMLNGFTELDENPRWKQGGPMAPFDKMFYISLGVSVGGFGDFVDHLRTATYEKPWANYHPQAKLQFHQAQDQWLPTWKQPALKIDYVRVFATDN
The following text describes a protein:
Function:
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential).
Subcellular Localization:
Mitochondrion.
Sequence:
MEKLRKVVNEIAYTRVHTNSPALHRSLVPFLTIASSLYGVALQIRRSLYRYSLLQKHRLPVPVISVGNLSWGGNGKTPMVEYISQFLVDSGLTPLILTRGYAGGDEVKMLERHLRGGPVKIGVGANRAATAALFLDKYGCVDSSSLRSFFDLHERAQVWTISEKIGCIILDDGMQHWSLSRDLEIVMLNGLNPWGNGHLMPHGPLREPLLALERADVAVVHHVDLITKQSLRDIENMIQGFKKSIPIFYSKMVPKYLFDVKNARSHVALEALRCASVLCVSAIGSADAFVKSIEMTGAHYVDRLDFSDHHLFEAEDVETMSRRAKGLEHKSNCKPIIVVTEKDYDRDPEILKCLDSYTVLVLCSELQITPILETDVDSFNYTLMKALAAKFYVSS