lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MILPAPHVEYFLLAPMLIVFSVAVAGVLAEAFLPRRWRYGAQVTLALGGSAVALIAVIVVARSIHGSGHAAVLGAIAVDRATLFLQGTVLLVTIMAVVFMAERSARVSPQRQNTLAVARLPGLDSFTPQASAVPGSDAERQAERAGATQTELFPLAMLSVGGMMVFPASNDLLTMFVALEVLSLPLYLMCGLARNRRLLSQEAAMKYFLLGAFSSAFFLYGVALLYGATGTLTLPGIRDALAARTDDSMALAGVALLAVGLLFKVGAVPFHSWIPDVYQGAPTPITGFMAAATKVAAFGALLRVVYVALPPLHDQWRPVLWAIAILTMTVGTVTAVNQTNVKRMLAYSSVAHVGFILTGVIADNPAGLSATLFYLVAYSFSTMGAFAIVGLVRGADGSAGSEDADLSHWAGLGQRSPIVGVMLSMFLLAFAGIPLTSGFVSKFAVFRAAASAGAVPLVIVGVISSGVAAYFYVRVIVSMFFTEESGDTPHVAAPGVLSKAAIAVCTVVTVVLGIAPQPVLDLADQAAQLLR
The following text describes a protein:
Function:
Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MEEKWKLSKKDTTASSSSSKSKFSRSFSTSASSTKSPIFVRSSSTKCSVPSSSSSSSSSSSISRSFSRKERRSSSSSSSSITQKYSSLAKEQKARFYIMRRCVAMLVCWHKHGDS
The following text describes a protein:
Function:
Regulates the RNA editing of the chloroplast transcript accD, and is essential for the early stages of chloroplast biogenesis. Required for the RNA editing of the chloroplast transcript ndhF.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MASSAQSPHFYLNPGKSNSFQSKAYKQRNVNFYWNFGIRRLFLRKSQGLSVLSSSSSSTHFSNSQLHGLCANGKLEEAMKLLNSMQELRVAVDEDVFVALVRLCEWKRAQEEGSKVYSIALSSMSSLGVELGNAFLAMFVRFGNLVDAWYVFGKMSERNLFSWNVLVGGYAKQGYFDEAMCLYHRMLWVGGVKPDVYTFPCVLRTCGGIPDLARGKEVHVHVVRYGYELDIDVVNALITMYVKCGDVKSARLLFDRMPRRDIISWNAMISGYFENGMCHEGLELFFAMRGLSVDPDLMTLTSVISACELLGDRRLGRDIHAYVITTGFAVDISVCNSLTQMYLNAGSWREAEKLFSRMERKDIVSWTTMISGYEYNFLPDKAIDTYRMMDQDSVKPDEITVAAVLSACATLGDLDTGVELHKLAIKARLISYVIVANNLINMYSKCKCIDKALDIFHNIPRKNVISWTSIIAGLRLNNRCFEALIFLRQMKMTLQPNAITLTAALAACARIGALMCGKEIHAHVLRTGVGLDDFLPNALLDMYVRCGRMNTAWSQFNSQKKDVTSWNILLTGYSERGQGSMVVELFDRMVKSRVRPDEITFISLLCGCSKSQMVRQGLMYFSKMEDYGVTPNLKHYACVVDLLGRAGELQEAHKFIQKMPVTPDPAVWGALLNACRIHHKIDLGELSAQHIFELDKKSVGYYILLCNLYADCGKWREVAKVRRMMKENGLTVDAGCSWVEVKGKVHAFLSDDKYHPQTKEINTVLEGFYEKMSEVGLTKISESSSMDETEISRDEIFCGHSERKAIAFGLINTVPGMPIWVTKNLSMCENCHDTVKFISKTVRREISVRDAEHFHHFKDGECSCGD
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system.
Sequence:
MKVELVTSLKRQATKILADLHETKEPVLITEHGKPSAYLIDVEDYEFMQNRLAILEGIARGERALADGKVVSHQDAKDRMSKWLK
The following text describes a protein:
Function:
Required for efficient transcription initiation by RNA polymerase I (Pol I).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKRSTANAPKLSPKHESESDPKKVKLEEEAKPTVNQAPTGREIVENYLKGDVTAAVLYRKICNALETFEQWESEAPKIQLLDQFLNIADAMEARTETLVKRLLSLRWDKIPGSVIERFRNFLCELAIRHLCFTEEVYSAVVERLVPQISVTEETGVVTLILTEKVQNEHFEMAHHIISSVLRCFPLSARALLKCVKRVMPHFTRPSVTVAGYMRNLILMQKYIPASISKDVWEAVFERLAKDDTHNWKCEQNEEMSKSPRLFALNDDILIEEVVEGNTNDSEDVTPEQLEQRKGEQMIQYLDSVCTDVITFIRSSVDSEIDEENGNERTKLNDKWLRNFKITGDKVLPKEKLFDTFLECLESTMLNATHVQYVSFIWLYFCSLSQEYEKKMLEHLWQVTIRMPRAPADARKSQGAASYLAAFLARAKYVKKSTAFTWLEEVYIWLRHYVDQFGSGSSQILPGLQRHGTFYSVSQAFFLVFAFRYKEFVKNKDMLETIRRWGVGRVVHSPLEPLKYVSKPVARCFSAITRSLQLVYCNHIIPIEEVQRPFDDMFPFDCYHLKESSKFMTPLMRKFSPLAEDMSTLTKALCWNAATADKSEKSAEAVSSSEGLDFLDEDDAMMMGGSSGYRERTFSCGQSSLINYSATPGLQTFNV
The following text describes a protein:
Function:
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus.
Sequence:
MSIVTLQLGQFGNQLGYEFFNTVLDDIYCFHGKNTLRKKLAATNKYNYEDAAFESFFYATSDLPLARAVMIDTEAKVVDDVFTKAKMSKLWSYDPKCCIRKKRGSGNNWALGYCMDGDQVLLEEIMDSVQRQVEYCDRFSGFLLLMSLAGGTGSGLGTRCTEELRDRYPNSQIINEVVWPYSNGEVIVQDYNTILTLSHLYKASTGLIILENDKLHEICTRLLKIKNVGFHHINRVIAHKLAGVLLPSTCLQNQHSKRNDYAGINIFGEIGEHLCSHTDYKLLNIIDIPQIPDHSFDYTNYNWHGLLKHLHQMLIANAFMEESKYTHIELAKLSSGLPVHSDVMVNKSIANMLVIRGTEIDKADIGAFRDSRLYVNWMPNSSGLATRVNSRPYNKYEKSAFLLSNSQFCIPTINNVTEKAWNMFANRAYIHQYISNGISEDDFIDSFATAEQIITNYNKL
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus.
Sequence:
MVKAAARPARRWACGPPGPAESAAAAAGASRASFPAASLSRRPGLAPPPAPERGAAAAAAAGAAAGHERGRPLAAAAAAAMKRDRLGRFLSPGAAGTAGKRGLAVAATSGPGSRARAPRAGVGGPGAEEDCEGVAVVPPRPGGSWGEDEDDAVTVSAAEDGPEEAGTGRPLSMGYCRLCHGKFSSRSLRHIFGRGPGESCEKQRRMEQAFFMDFKRLLGVPIRQDPALPQFVCKNCHAQFYKCHSILKSFLQRVNTSPTGHRKPRGKGSTEEGSQAEAEEGACLVDLITSSPQCLHRLVGWAHGHAASCGAVPSLQNMLSSEYCGIIQAVWGCDQGHDYVMDTDSNCSSLLLDSTLAVKWEWDRETAHRLSNNSGTKPPAAVLQSPRSKGTTVPAGAESQSLPNTNEAQPPLDDNPVGPEPDSPPEPSQPLSGVQGQLSVKQVSSSALDDRVKDEFSDLSEGDFLSDDENDKRKNTQSSDESFEPYPEKKVSGKVSDSKEVKKSDEPKIRKKPGPKPGWKKKIKCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLSVHQMRHSGAKPLQCEICGFQCRQRASLKYHMTKHKAETELEFACDQCGRRFEKAHNLNVHMSMVHPLTQNQDKAKPLQNEQPTGLMNPSGTMESQAVKPELVAQQEPT
The following text describes a protein:
Function:
May be a substrate targeting component of a cullin-RING-based E3 ubiquitin-protein ligase complex RTT101(MMS1-ESC2). Involved in HMR and telomere silencing via the recruitment or stabilizing of the SIR (silent information regulators) complex.
Miscellaneous:
MISCELLANEOUS: Present with 1890 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The 2 SUMO-like regions, although related to ubiquitin domains lack the conserved acceptor Gly residue in position 456.
Sequence:
MTGDSRSISEPSINLDPDNTSFSDENSDDFFMDNSYDIDEIDHSDESNRQSVIVDSKVTVPPSKHSTLTLSDSEDSDAKEQHQSLSRSSSKNVNIEDITEPKPDKPSGRTRGRSVMKESVVEINSSESDLDEDKNFPRSRSRSRSSIRSISPAGKYKRQKSSLLYTYDENDDFFKELAKEAKKSTTISKESTPDQRKRVYNIKFLSKLEGTINKAVQVKVLGKYEFSKILPAALDGLMKSYKIPKVMKDIYKVENVTLYWNNAKLLTFMTCNSLHIPQDFENEVSDIDVTIVSKEYEKNFEATLESKLKEEEAALLIKERQEMERKLEKKRNEQEESEYREFESELKNVEETQEIKENDTVMNTKLLQEGGSLSGNSSSMEEVMRIALMGQDNKKIYVHVRRSTPFSKIAEYYRIQKQLPQKTRVKLLFDHDELDMNECIADQDMEDEDMVDVIID
The following text describes a protein:
Function:
Antimicrobial peptide active against the Gram-positive bacterium S.aureus (MIC=25 uM) and against the Gram-negative bacteria E.coli (MIC=6 uM). Has no antifungal activity against C.albicans. Shows hemolytic activity against human erythrocytes only at high concentrations (LC(50)=180 uM).
Subcellular Localization:
Secreted.
Sequence:
GVLGTVKNLLIGAGKSAAQSVLKTLSCKLSNDC
The following text describes a protein:
Function:
Transporter for myo-inositol. Also appears to transport the polyketide mycotoxin fumonisin B1 (FB1). Does not appear to transport hexose sugars.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGKSRQNSTTTVDREKDEIQKAMGHEKAEFEALEVARHGGREIDDLIDDMERQLDEAGGLNKGFFQVQFANPKHFTWLLVAFASMGGLLSGLDQSLISGANLFLPDDLGLTEHENSLVNSGMPLGAVGGALLLSPANEYFGRKGAIIISIILYTIGAALEAGSINFGMIVSSRVILGLGVGLEGGTVPVYVAETVERRIRGNLVSLYQFNIALGEVLGYAVGAIFLNVPGNWRYILGSSLLFSTIMFFGMLFLPESPRFLIHQKRHLDAYKVWKRIRGIEDRESREEFYVMSASVVSEENAVAEGAKNHRFPWMDFFTEPRARRALVYANIMILLGQLTGVNAIMYYMSVLMNQIGFDKKESNYMSLVGGGSLLLGTIPAIFLMERFGRRFWAITMLPGFFIGLVLIGVSYQFDVETQLQTVEGLYLSGLIIYMGFFGSYACLTWVVPSEVYPTYLRSYGMTTSDALLFLASFIVTYNFTAMQNAMGKTGLALGFYGGIAFIGEIYQIFFMPETKNKTLEEIDVVFSRPTMDIVRENWAGVKETTHLLLTGHWHKVFVEQAMTDPKDQVQVSHA
The following text describes a protein:
Function:
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer.
Subcellular Localization:
Nucleus.
Sequence:
MKVASGSAAAAAGPSCPLKAGKTAGGAGEVMRCLSEQSVAISRCAGGPGARLPALLDEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSRVEILQHVIDYIWDLELELNSESQVGTPGGRGLPARAPLSTLNGEISALAAEAACVPADDRILCR
The following text describes a protein:
Function:
Deubiquitinase which hydrolyzes the isopeptide bond between the ubiquitin C-terminus and the lysine epsilon-amino group of the target protein. May negatively regulate inflammatory and pathogen recognition signaling in innate immune response. Upon phosphorylation at Ser-202 and Ser-204 residues, via IL-1 receptor and Toll-like receptor signaling pathway, specifically deubiquitinates 'Lys-63'-polyubiquitinated MYD88 adapter protein triggering down-regulation of NF-kappa-B-dependent transcription of inflammatory mediators. Independently of the catalytic activity, acts as a scaffold for alternative deubiquitinases to assemble specific deubiquitinase-substrate complexes. Associates with USP7 and USP9X deubiquitinases to stabilize alkylation repair enzyme ALKBH3, thereby promoting the repair of alkylated DNA lesions.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDGQGGKGTVAHSKDEAAMDSYLRSEGLYRKKIAKDGSCLFRAVAEQVMHSQSEHLKIRKSCINYLRKNRGQYEALIEGSFEDYLKSLENPQEWVGQVEISALSLMFKKDFIIYQEPNVPPACVTENGFSEKIMLCFSNGNHYDIIYPIGFAESAAMCQSIIYELLYEKVMGVNVGKYMVEQDTCGPNATGEVYCSDGSGSEGEDVSKNIKTNFADMNGFKPHKDDKCPQKKKEEPTMLPSVLRSLHTTQYRNVEYEVWLKTQRDQQKLDFSIAAGMQYSVGDKCQVRVEPGGKFYNAHIQEVGTETGPVIVFVEELGEKHAVQLKHLKPIPQTIISTEGWNTVAGKKQKKALPSGTNAQTEKDYRGQKGFGKPVKQQAAQPLRQQQAAGNKQYGLSSQLSDQAPQSENKGRSKTPPKVPGRKVERERSENVTFGLTVEERKEKEAIEESKSLYEMQSMDKDAFPALSSLPIGERAVQNTEVFPVKRIPNVITENTRRKSEGEDQRDKASTAQATKGRDQKCCDETVKQLTSSDADDLPSMPVLRTSAEHQASPIVPSTPSVVTSWPGIPAQIPSMSATGSDSSVLQPQVTSSPYPPLPVSVPAVNQPLLPLPQTLSALQDPLYPGFPLNEKGERATVPSYSFCKNGGDLPDDKSILRFFFNLGLKAYTYPMWPPHTHLYPLHQAYLNMCRMYPNIPVYPQGSWVQETSENQSEVDPSLLSHPSEVRMESQGSQPLTVSSSPVQVPGIVGQIPNQSESGVINQALHTNVDFEDPATSKTIFPQPPFAQSSYMGAVPIATPYFPHFWYGYPYQGYIESPVIRHNVYIPPQDRDLPENLSSEAVENNSSNQIAIRQSLDLQEQCKPDLPLASSTGGTSSELISNASTVQSEQRMNVNIPQVLTGHKSLPSKMKDNLVPPLASTPIETKETAYGSSEDKERSEVNAVALGSTQANVSEEKALRAREESSEDEREVSNMLSSGRSKNFYSQSYSTRRPRSEKYYQPNRGGYQHPRGEEGWRGQRGRDDGFQHHRSYRGRPYRRRPMGDSYRAQQE
The following text describes a protein:
Function:
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MKKKGKSNDEKKFILYDIMLESESFFILKELESLAPKKGIRSIFVKDLLQQLVDDDKVKSEKVGLQNVFWVLKTEESSILQNKYQELMEQKRDYEEIIKKEKEEYDKLMHSLKYSEEELQKQVGDVKVLLNVLEKKKMELQDLKKTDIKQIEKMKIQNKCAVESILRWNNNIFIVKQWIQNRTDKPGDIVDRLLGVKDIFHNWN
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MSKPATTLDGLQDGSVELQKRLSAKRDAEGELKHEEDRKLRKEGKTQTPVTNQEGDVLNPYIPRFMSSAPWYAKAGDDDPSASSLDHLKKDKTDSKKEEWYARGQDRSSLERPKKFRKGACENCGAMTHKKKDCMERPRKVGAKYKADNLQADDVISNPHMSWDSKRDRWNGYDAEDFKRVIDEHNMTEELQKKLHGDAPAETDAEKAAAVEEAIRKSTRTLRLREDTAVYLKDLNSETVYNPGSRTFRTADEGYIDKDGMFVRHTTGEGKEMEELTRIAEAESALGNQIHLHANPTAAAIAAKRIKEEAEKAKDAEKRALEEKYGKQDHVRVRPKEYTSVVTAKKPTVIRAKNAQGIAVSKYEEDVFPGNHTSVWGSYYDKETAKWGYACCHCLIKNGYCVGEKGKKKKGAMDTV
The following text describes a protein:
Function:
Receptor for the peptide pheromone P-factor, a mating factor of S.pombe. Pheromone signaling is essential for initiation of meiosis in S.pombe; P-factor signaling alone may be sufficient.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRQPWWKDFTIPDASAIIHQNITIVSIVGEIEVPVSTIDAYERDRLLTGMTLSAQLALGVLTILMVCLLSSSEKRKHPVFVFNSASIVAMCLRAILNIVTICSNSYSILVNYGFILNMVHMYVHVFNILILLLAPVIIFTAEMSMMIQVRIICAHDRKTQRIMTVISACLTVLVLAFWITNMCQQIQYLLWLTPLSSKTIVGYSWPYFIAKILFAFSIIFHSGVFSYKLFRAILIRKKIGQFPFGPMQCILVISCQCLIVPATFTIIDSFIHTYDGFSSMTQCLLIISLPLSSLWASSTALKLQSMKTSSAQGETTEVSIRVDRTFDIKHTPSDDYSISDESETKKWT
The following text describes a protein:
Function:
RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs. Seems to recognize a GAAA motif. Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR.
Sequence:
METQLSNGPTCNNTANGPTTVNNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKSRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA
The following text describes a protein:
Function:
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Subcellular Localization:
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Sequence:
MEQLFREAQDALAAAGPLCQESQDVLARARQNLEVAVHLGIRTQFLAKAHAHQWTLASKFYSNALTRTKKSLETVTRQQTRFQAARGALEEALGELAATPVQLRVNNGAHNLREFVDEDLISAQVQGKGWNEVHEEALNVFRVLLPEIQRHGDIVNRSKKEFEREKAEQTELLIHQTSDSGIYDLLNSAEACSEDMANLLQSLARHYDLCERGQDLSTGAIEAEDVNELGELRAVLENDAQQLPDVLDELQERLDEVKQGCQGVHNHMTQMYHSYSLEVRQLEGIQAVEKTMDATLEICETQQRDTKEYLLKVQRYVSETSAVVTHYQTFLNSYKALLHEAERRNAAEAKMKDYVTEVNAKLAQMSIQETNRRQDFVAQQGDYLPADIWDELLLPSRRFEARELDGEL
The following text describes a protein:
Function:
Converts unsaturated trans-2-enoyl-CoA species ((2E)-enoyl-CoA) to the corresponding (3S)-3hydroxyacyl-CoA species through addition of a water molecule to the double bond. Catalyzes the hydration of medium- and short-chained fatty enoyl-CoA thioesters from 4 carbons long (C4) up to C16. Has high substrate specificity for crotonyl-CoA ((2E)-butenoyl-CoA) and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA (3-methyl-(2E)-butenoyl-CoA) and methacrylyl-CoA ((2E)-2-methylpropenoyl-CoA). Can bind tiglyl-CoA (2-methylcrotonoyl-CoA), but hydrates only a small amount of this substrate. Plays a key role in the beta-oxidation spiral of short- and medium-chain fatty acid oxidation. At a lower rate than the hydratase reaction, catalyzes the isomerase reaction of trans-3-enoyl-CoA species (such as (3E)-hexenoyl-CoA) to trans-2-enoyl-CoA species (such as (2E)-hexenoyl-CoA), which are subsequently hydrated to 3(S)-3-hydroxyacyl-CoA species (such as (3S)-hydroxyhexanoyl-CoA) (By similarity).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MAALRVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
The following text describes a protein:
Function:
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MVQRTRWRYSAIAHNYNSCRPMELGAGIAVGAWDGVWARARSAEFVAATDMGDPVYSAFMRYDDSAPLHAAVAADWATYVAADFNGGPFKYSIFPILYSFTASLVVTMGLTVIVFFNVRTKPHRGVPKLLRVAAVLACGNLLTFVVRAMMQLGRDHAEGVVPMNHILDMLWTDTAFNTVDILAVLILQLCQVQTVMRFFTRFQEKRLISLCGILLAVLSQVLWAIPPYSEAVSNHFMPLDDDKDMDVLPPFVYLVRIAQAGSYASFVLMHVFAKKKLCVQSVQMFLLTVLTVVVVVLQPAFFITDVTNVWIDNLSEIFSTTCYMGSTVIVWEWSNRLSILEARRQAQSILGRPVYEDEEQGYNFARYALKIQTALTSKSDEGDTTSATTFAAPRSARFEGKGGPQSPVYVQEGEQQAVMAFNKRMGTRALAHHVLDSIIYYTDKVVVKGLGNLSASLPSKTSSATSVRGRVRKRIGLEGANDVFVYRTKDLVFDSDEDIPRT
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Sequence:
MSDPWARYEAWRTAGGIGRNANMMRLLPGFLIGTGLFVVAVGVESVMSKGQKKH
The following text describes a protein:
Function:
Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts.
Subcellular Localization:
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Domain:
The CRIB domain mediates interaction with CDC42.
Sequence:
MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRRLTADMISHPLGDFRHTMHVGRGGDVFGDTSFLSNHGGSSGSTHRSPRSFLAKKLQLVRRVGAPPRRMASPPAPSPAPPAISPIIKNAISLPQLNQAAYDSLVVGKLSFDSSPTSSTDGHSSYGLDSGFCTISRLPRSEKPHDRDRDGSFPSEPGLRRSDSLLSFRLDLDLGPSLLSELLGVMSLPEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSAPAATPTGPAANPPAPAASSTPHGHCPNGVTAGLGPVAEVKSSPVGGGPRGPAGPALGRHWGAGWDGGHHYPEMDARQERVEVLPQARASWESLDEEWRAPQAGSRTPVPSTVQANTFEFADAEEDDEVKV
The following text describes a protein:
Function:
Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis. Mediates inactivation of the TORC1 complex in response to amino acid starvation. Post-transcriptional regulator of nitrogen permeases. May be involved in putative NPR1-dependent phosphorylation of nitrogen permeases or in the processing and targeting of nitrogen permeases at the level of the endoplasmic reticulum.
Miscellaneous:
MISCELLANEOUS: Present with 319 molecules/cell in log phase SD medium.
Subcellular Localization:
Vacuole membrane; Peripheral membrane protein.
Sequence:
MLSYFQGFVPIHTIFYSVFHPTEGSKIKYEFPPNNLKNHGINFNTFKNYIIPKPILCHKLITFKYGTYRIVCYPVTINSPIYARNFFSFNFVFVFPYDCETSPYEPAITRLGKMFKVLEEQNQLLSKSERDPVFFDLKVLENSTTTPSTAGPSSTPNPSSNTTPTHPTSEKDTKDMRSSRYSDLIKDLGLPQSAFSIQDLLMRIFQDLNNYSECLIPIDEGNAVDIKIFPLLRPPTTCVSLEDVPLSSVNLKKIIDVNWDPTMMSIVPYIDGLNSIAKISKLSNSDPGLVIECIRHLIYYKCVTLSDIFQFSNIYAPSSLIRNFLTDPLMASDCQSYVTFPEVSKISNLPLNKSLGSGDQDSPSFSVRRKSKSSSIPSNPDSRTTSFSSTSRVSQNSSLNSSFSSIYKDWRQSQTSCSSSNIHVINNRNRFLPTRSCLFDLYRSLSQGQTLKTWYESKYMILKENNIDIRRFITFGLEKRIIYRCYSFPVMINAGSREPKEMTPIITKDLVNNDKLLEKRNHNHLLSATGSRNTAQSGNLKPERPSKVSFEMQRVSSLATGKSTMPKLSDEEEGILEESIRNAETFDKICVLLSKPKLEVESYLNELGEFKVINS
The following text describes a protein:
Function:
Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor/signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane.
Subcellular Localization:
Membrane.
Sequence:
MNNRFSIALFLTIIMTNIILYFFLPLSIVTKWDFNGMPTSTMDKSTFVIVNIIICSFLFFVFLALSKAASNQKFFHWIGNTMLLFLFFVDIVIALIALGFSLPLDHFIFLALGLLFILIGYFSSKIDTTKSTVSLEWNDKHLKKRASNISSISMMIAGIFLAILPFIVSAPYRGYAILAILLGMTLIILPSTIYLLIKDSKQSTP
The following text describes a protein:
Function:
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGGGQREVGEGSNVKANAKRRRRTWLKRKEKWLVVLGVVLHAVYMLSIFDIYFKSPIVHGIDLVTPRFKAPAKRLVLLVADGLRAEKFFESDSEVKFRAPFLRSVIEEKGRWGVSHPRPPTESRPGHVSIIAGFYEDPSAVTKGWKANPVEFDSVFNRSRHTFSYGSPDIVPIFCAGLPHTTWNSYPHDFEDFATYCDYYCFFSSPSTLMLTLYQFVCVNADASFLDECSFDQFKGLLNRSKEDPKLKELLLQDNLVVFLHLLGCDSNGHAHRPSSSIYLNNVAVVDSIAERVYNLLEDYYRDNRTSYIFTADHGMHDKGSHGDGHPSNIDTPLVVWGAGVKHPKPVSSSNHSDCGFRFVDEHMHETPTPTEWGLHGIERVDVNQADIAPLMSTLLGLPCPINSVGSLPLDYIDMIKEDEVEAVVANTKRILNQFLWKSQTKQSNSLYFKPFKPLGDYSSLLDKIEDLISIRDYAAARKLSEDLQVLALQGLHYFQTYDWLMLMTVIILGYIGWMTYIVLHVLQSYTSLAGYMFRKEQADHQTDNTRKEHSPPLYHSYTSMTVFLWTQIFSEYRFIKALWKELYGRRINYFAKILATGIFSVFILEFLVARSAYEGNKCWLSICNHDKKQPKFPMLFQLQALLIGLSSVMVSISTSRRTQKQELLALHQITNWSIAGISIVLPLFSANGLLSRLTSLFLGFAPTFLLLSIGYEAVFYGALALTLMAWILVENTFIYSSKVNRLPSSFNNMEDNVILDGRYLQLSDVRIPLIFMVLFNVAFFGTGNFASIASFEISSVYRFITVFSPFLMAALLIFKLFIPFLLVICVFSAITKLNRLPRLGCYFLLILFSDVMTLHFFFLVRNTGSWMEIGNSISHFGIVSAQVVFVLLLFAVTNMYTKDVNIGSADRSSRKAM
The following text describes a protein:
Function:
NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form.
Subcellular Localization:
Cytoplasm.
Sequence:
MDSHSPIATVAQALRRAERILVITGAGLSADSGMPTYRGLGGLYNGRTEEGLPIEAALSGPMLRRDPALCWKYLAELGKACLAARPNAGHEAIAELQKHKPECWVLTQNIDGFHRQAGSPAERLIEIHGELAPLYCQSCGAESGGLEEHLHGQLPPRCAACGGVLRPPVVLFEEMLPEEAIDTLYRELRKGFDAVLVVGTTASFPYIVEPVLRTRQAGGFTAEVNPGVTDLSERVDVKMTGRALDIMPQVVSHIYR
The following text describes a protein:
Function:
Synaptic adhesion molecule. Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with presynaptic neurexins (By similarity).
Subcellular Localization:
Postsynaptic cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Most prominent in the postsynaptic specializations of asymmetric (type I) synapses.
Domain:
The cytoplasmic domain binds synaptic Ca(2+).
Sequence:
MARMSFLSFLLFCLTSVAHGNKANKHKPWIETEYQGIVMENDNTVLLNPPLFALDKDAPLHYAGEICGFRVHNGPGGSGSAQFEAVVLDRSTGEGLVRSKEPLDCESQKEHSFTIQAYDCGEGPDGTNSKKSHKATVHVRVNDVNEFSPVFVERRYEASVPEGRLFDRIVRVEAVDADCSPQYSQICFYDIITPNVPFTIDNDGNIKNTEPLDSKRQRVHSFWVTAFDCGKNRAQADAQVIVTVKPSCKPGWIGWTKRIEYTPGSGSIPLFPNLHLETCEETVWNIQATVELQTSHIGKGCDRDSYSDRSVRRLCGAVRGEVDLLPPPSPATNWTAALPTLPSSDSSLVFSFNGSTHVAVVPDSVASAVSGDHFTLQLWMRRGGASTQPPANQARGTRKEEETIVCSTVKNDDSYSHYSLSVHGCRLSLFYWPDVSAARPVKFLWKLEQVCDSEWHHLSLSVQFPSVTLYVDGVTFDPALIHDNGAIPNPAPHQRLVIGACWEPEEKPKDIVNNTMPENKDTGKFVSGYKGLLSGVTVRPGNVEPHSVVECLYACREGLDFGDLETLGSGMKVHVNPSQSVLVLEGDDIESFNRAVQQVTYRNSLRFATPGVRPLKLTTSLRCFSEESCLSLRQLEGYLVVLQPDAPQISLSGVGPHLARPAAEFEGPQGVPLFPELRIVCSLSHAVNTAAQGMEGGALMSDAVAHTLDGCEVQPLGEELNTEREELLVDMESLRERGLDIINTTAYIAITGAESISVYEDVLRSIHYRLAKGSARFERRFRLSCSEMNGRYTSNELTLEVNFLHSLDSLYHPSHLLASQQQFLHPSHHTGELSGHTLPNPHRNSVVPGAATVIIMVCVGFLVVMVILGVFRIRSIHRRGEGARGGGKEGGNQWDDSALTIIVNPMETYENRMGITTDMEGECEDEEEVVDSPDDTSDDQRIIIKKEGRDSAPRRY
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Sequence:
MSFWKNLFTSAFTPISAEADELIKEDRKQFEENTPSKKNFETQSPDEPSPKTTDSTGARDANLSLKTQEPIVSADDAKGAQGKGADEKEEKKETIQPPEEVKTEPPQPEEKEGKEAKEPEEPPKEEAEEPQEGGEEEEEEEEEEEITDPLEKMTQECMDAPDCKEVKHHFEECTARVTKKVEQGDKSEDCIEEFFHLYHCARDCADPKVFKVLV
The following text describes a protein:
Function:
Has antimicrobial activity against E.coli (By similarity). Plays a role in the defense response in the male reproductive tract, contributing to sperm maturation, storage and protection (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MIPRLLPFFASLLFAALLFPGDIPPGIRNTVCLMQQGHCRLFMCRSGERKGDICSDPWNRCCVPYSVKDRR