lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MFACLFSFIMSTAKLQFTHRRGVDTIMAVRMRLVGTMTAIILIMFILAQGLECSQTCKCDQMYFCNCSSNNLHQVPTVPSDVLGLDLSFNQIESINMTDLSSYNELIILNLHKNKLRHIHRDAFKSQHNLEVLDLSLNNLNNLSPSWFHKLKSLQQLNLVGNPYSTVGPAPIFKSLVNLRTLHLGSPSLRELHKNGLDVLTHLDEMTFFGSNLRSYENGSLKAARPIGSVSLSLQNLFESDPELVSKVLQDVSHPETLLIIKDVTMKTNTSTEPFKMVKEGGTKSLTFQNSSTTDQALTSFLEFMDGSPLSFIGLEDIQFVGIGEWQKAKYTHHDSLRTAYLRNIEIEGFFGFSSMIELGFLLKHFHNVSVINATVFVIPKETTFLLKNLEYMDLSQNLLTDLTIQPTLYTGSGAYQNLNMLNVSQNVLKSLGLMSRLVTNLKKLKYLDLSYNSFVSMPEKCSWPVTLRFLNLSSTKLSTLTPCLPSSLTVLDLSENDLKAFKQRFPHLTTLILTGNRLMKLPDGKLFPSLNTLLIQRNALRMFNQSSLRSFKTLLYLEAGANNFVCSCKFVSFFKKDVEDLITLQDGRQNYVCNTPFTLRGNAIDSVRLSVFECYMIPAVSVLCFGIITALGLVVLTCHKLHVIWYLQMTKAWIQAKRKPAVGRLPEELRYDAFVSYSQHDAEWVEEILVAELEDTQPSFSLCLHKRDFRPGRWIVDNIIDSIEKSYRTLFVLSEHFVSSEWCRYELDFSHFRIMDEHNDSAVLVLLEPIKKETIPKRFCKLRKIMNSRTYLEWPEDEDKRDEFWSNLRAALQRDEC
The following text describes a protein:
Function:
May play a role in chromatin organization.
Miscellaneous:
MISCELLANEOUS: Present with 3570 molecules/cell in log phase SD medium.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MHYVVLELQVAHLPDTPKDQCRIANIAFQIVNAETLVCHYGTNSLPSIEVNGTTKSLESAMVQLDKDIHDVIGNDDFVLVSLYSTWHIRVTLPRQARDDGFILTSYLQHPKVFDLWKEFDRWCVNHPEILGQKKAISNNNCNTKSISINAAKNTKDLDEIVRILEVSIPTEEAGSVPEIYSLLKRTTDILIQLHKKCTSPEDMESVLTKPYDSHTDIRAFLQEKSKILYMNNLPPDTTQSELESWFTQYGVRPVGFWTVKNIVEDTSNVNNNWSLNNSPYVEDQDSISGFVVFQTHEEATEVLALNGRSILSNLANTKQPRVVEHVLELQPSSTGVLDKAQEILSPFPQSKNKPRPGDWNCPSCGFSNFQRRTACFRCSFPAPSNSQIHTANSNNNVNSSRNNLNNRVNSGSSSNISNTAANHPYGAPEFNMIANNTPAALTYNRAHFPAITPLSRQNSLNMAPSNSGSPIIIADHFSGNNNIAPNYRYNNNINNNNNNINNMTNNRYNINNNINGNGNGNGNNSNNNNNHNNNHNNNHHNGSINSNSNTNNNNNNNNGNNSNNCNSNIGMGGCGSNMPFRAGDWKCSTCTYHNFAKNVVCLRCGGPKSISGDASETNHYIDSSTFGPASRTPSNNNISVNTNGGSNAGRTDGNDNKGRDISLMEFMSPPLSMATKSMKEGDGNGSSFNEFKSDKANVNFSNVGDNSAFGNGFNSSIRW
The following text describes a protein:
Function:
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
Sequence:
MHEMVATDKQVLLPISLVSLRTFVEVARCGSMKDAARNLGVTPGAVSQQIKIVEERLGAPLFERASKDLHLTAEGVRLIEALNMPFQQIQDAVEDFDHRKPKRNTLVVTTVPSFASSWLVPRIGKFAKLYPDIEVKVDSSVALVDLRHEPFDIAIRHGSGNYPGMSVTQLLTPQLVVVASPEFLRNIPSIQTPADCLAHPLLQDRDRVDWPRWFRAHGINDATGRAARGSSFSDDSLMIKAAVASQGLALVRDIYAEEAISSGLVRIPIAASLGTPLSYYFVTRMQDAQKSRIQAFRNWLLGEIASRPKLT
The following text describes a protein:
Function:
Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, and to a lesser extent, of pivalyl-CoA and isovaleryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. Also displays ATPase activity. Is not able to convert 3-hydroxybutyryl-CoA to 2-hydroxyisobutyryl-CoA. Does not exhibit methylmalonyl-CoA mutase (MCM) activity.
Domain:
Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
Sequence:
MAHIYRPKHHVRFVTASSLFDGHDASINIMRRILQASGAEVIHLGHNRSVEEIVNAAIQEDVQGIAVSSYQGGHMEFFKYMYDLLQERGASHIRIYGGGGGVIIPREIKELHEYGIARIFSPEDGRRLGLQGMINVMLEECDFPTVTVVTDELERLPSGDVQAIARLITLCEYRAEGENKEAAAAAEAAIEQVKALEKRVPVLGITGTGGAGKSSLTDELVRRFLNEIPDIKIAILSVDPTKQKTGGALLGDRIRMNSINSPRVYMRSLATRHSRTELSPAIRDAISVVKAAGFDLVIIETSGIGQGDAAITEVCDVSMYVMTSEFGAPTQLEKIDMIDYADLIVINKFERKGSEDAKRQVQKQYQRSHQLFDRDVSEMPVYGTIASQFNDPGTNTLFVALVDTINKKAGTNWKTSLKTVANVEKHNVIIPNERRYYLREIAETVRSYHRRAEQQVEVARRLFQIEGAIEAAKERGEAEDVIRALETLKADYEAKLTPESKRILATWEETKAKYAAKQFVTKVRDKEIVTELTTKTLSGLDIPKVVLPKFKDYGEILRWVYKENVPGSFPYTAGVFPFKRQGEDPKRQFAGEGTPERTNRRFHYLCKEDKAKRLSTAFDSVTLYGEDPDYRPDIFGKVGESGVSVCTLDDMKKLYKGFDLCDPLTSVSMTINGPAPILLAMFMNTAIDQQVEKKEAELGRPLTPEEYEQVKEWTLQTVRGTVQADILKEDQGQNTCIFSTDFALKMMGDIQEYFIKHRVRNYYSVSISGYHIAEAGANPITQLAFTLANGFTYVEYYLSRGMHIDDFAPNLSFFFSNGLDPEYSVIGRVARRIWAIVMREKYGANERSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALLAIYDNCNSLHTNAYDEAITTPTEESVRRAMAIQLIITKEFGLTKNENPLQGSFIIEELTDLVEEAVLQEFERLNDRGGVLGAMEMQYQRGKIQDESLYYETKKHTGELPIIGVNTFLNPNPPSEDELNNIQLARATYEEKETQIRNLREFQERNKDKAGPALERLKQVATSGGNIFEELMETVKVASLGQITRALYEVGGQYRRNM
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Sequence:
MFRILVLGSGAIAGLYAGKLVQAGCKVDFWVRKNSYELKRNGFQIESAPWGNFHYKVEKIFESIPKNLKEYDLILNCLKCLPDINLKKILGEKIPPNLPILLLQNGIGIEEPVSILYPENEILSGLAFVCANRLDAGKILHLDYGELTIGSWNRNPSFICDQLVNLFNSVGVPTQNTNTIRQARWKKLMWNAPFNPISVLCGGKNTLEILENPHSCKLVIEIMKEVQTLSKLDGAEVPSTQIDIFLQMTKTMKPYKTSMLLDFEAGRPMEIEAILGNTIRIAEKNNLEIPHIQTIYSLLNLYES
The following text describes a protein:
Function:
Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
Sequence:
MEFAAENEGKSGGGLHSVAEGVRLSPDPGREEVRDLARAEEVGGGEEGKGLTGMKEIGDGEKGSGQRPEEIPMDLTVVKQEIMDWPDTEGRLAGQWVKQEVEDRPEVKDENAGVLEVKQETDSSLVVKEAKVGDPEVKEEKVKEEVMDWSELKEEKDNSEIKQEEKFVGQYIKEEVMHGECVKEEKDFLKKETVDDTKVKEEPPINHPVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKKHKAELTCNGVRDKTAYVSIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRPISNKHMYFMKNRARRQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAEYIEKRVPDDKTINEILKPYIDPEKSDPVIRQRLKAYIRSQTGVQILMKIEYMQQNLVRYYELDPYKSLLDNLRNKVIIEYPTLHVVLKGSNNDMKVLHQVKSESTKNLGNEN
The following text describes a protein:
Function:
Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Single-pass type II membrane protein; Intermembrane side.
Domain:
The CHCH domain contains a conserved twin Cys-X(9)-Cys motif which is required for import and stability of MIA40 in mitochondria.
Sequence:
MLSSKLVACSAGRSVQRISRTFLPAMRGVATKAAAGPSRQSALSSYSIAAVTAIGVGASFYALQSRSSAIQCEPRQAWHDRLKPKEAKGDATLHKDAHTRHAPAEVQDERVEPVEETPVAIEVAVEESEEQTGQQSAYDPETGEINWDCPCLGGMAHGPCGEQFKLAFSCFVYSEAEPKGIDCVDKFKAMQDCFREHPDVYKDEIEDDEAANAQFEKEEANAKSNGLNDAAQEAVEESSGGKEGASA
The following text describes a protein:
Function:
Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult bone.
Subcellular Localization:
Cytoplasm. Secreted.
Sequence:
MQAAWLLGALLVPHLLSFGHGARGHGKEWEGVWGGALEEERDRESLMLKNLQEALGLPTGVGNKDNLAENSEGKEVWEATETQGEEEEEETTTTPSSSPTPFPSPSPTSEDTVTYILGRLASLDAGLHQLHIRLHVLDTRVVELTQGLRRLRDAASDTRDSVQALKEVQVRSEQEHGRLEGCLKGLRLGHKCFLLSRDFETQAAAQARCKARGGSLAQPADRQQMDALSRYLRAALAPYNWPVWLGVHDRRSEGLYLFENGQRVSFFAWHRALSPESGAQPSAASHPLSPDQPNGGILENCVAQASDDGSWWDHDCERRLYFVCEFPF
The following text describes a protein:
Function:
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
Subcellular Localization:
Cytoplasm.
Domain:
Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
Sequence:
MTTTPPVLSGPEIRQQFLNFFADRQHQILPSASLVPEDPTVLLTIAGMLPFKPIFLGQKSAEFPRATTSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGDYFKSQAIAWAWELSTQVFKLPAERLVVSVFEEDDEAFAIWRDEIGIPAHRIQRMGADDNFWVSGPTGPCGPCSEIYYDFHPELGDEKLDLEDDSRFIEFYNLVFMQYNRDNAGNLTPLEKKNIDTGMGLERMAQILQKVPNNYETDLIFPIIQTAANIAGIDYAQANEKTKVSLKVIGDHVRSVVHMIADGISASNLGRGYVLRRLIRRVVRHGRLLGINGEFTTKVAATAVQLAQPVYPNVLERQSLIEQELQREEAAFLKTLERGEKLLADLMADGVTEIAGADAFTLYDTFGFPLELTQEIAEEQGITVDVEGFEKAMQEQQERSKAAHETIDLTVQESLDKLANHIHPTEFLGYTDLQSSAIVKAVLVGGELVDQAVAGQTVQIVLDQTPFYGESGGQIGDKGFLNGDNLLIRIEDVKRESGIFIHFGRVERGTVQIGTTITATIDRACRRRAQANHTATHLLQSALKRVVDEGISQAGSLVDFNRLRFDFNSPRAVTMEELQQIEDLINQWIAEAHQTEVAVMPIADAKAKGAIAMFGEKYGAEVRVIDVPGVSLELCGGTHVANTAEIGLFKIVAETGIAAGVRRIEAVAGPSVLDYLNVREAVVKELGDRLKAKPEEIPDRVHQLQQELKASQKQLEALKQELALQKSEQLLTQAQTVGEFKILVADLGTVDGESLKTAAERLQQKLGESAVVLASIPEEGKVSLVAAFSPQLVKTKQLKAGQFIGAIAKICGGGGGGRPNLAQAGGRDASKLPEALATAKQTLLAELG
The following text describes a protein:
Function:
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAPQGFWLSREGFTADVTGKFLQRTILSPWKTLPLLLLAHYTSKGQATALNHPKAFRALKILATFAIIRRINAWLNQRVLNNGLTDQYHWHREVVVLTGGSSGIGRQIAQLLGNRGIKVAILDIQPPQDGQANLPSTVRYHKCDITSPSAIAEAAAAIRTTMGEPTILINNAGILSSRTILGSTESQTRLQFEVNTLSHYWLAKEFLPGMIKNNHGMVVTVASQAGYTVTPNMVDYSATKAAAIAFHEGLGAELVTRYNAPRVRTVLITQSFVNTGLIDKLTPEDTWLHPLLNPETVAEGIVEQVLSGKSGHVLLPGSTGWLAKCFRGFPLWFQHANRIKLEKLMRAD
The following text describes a protein:
Function:
Together with Abl, involved in embryonic neural development. May have a role in eye development. Acts as an adapter protein for SH2-domain containing proteins during sevenless (sev) signaling.
Subcellular Localization:
Cytoplasm.
Sequence:
MVKSLVAKLSTASSNLSLASTFGGGSGAAEETNYAKHRNDPGRFFGDGVQFKAKLIGILEVGEARGDRMCQEALQDLKMAIRAAGEHKQRITIHVTIDGLRLRDEKTGDSLYHHPVHKISFIAQDMTDSRAFGYIFGSPDSGHRFFGIKTDKAASQVVLAMRDLFQVVFELKKKEIEMARQQIQGKSLHDHSSQLASLSSLKSSGLGGMGLGHSDLASGGISSGHALTLLGSSLSTTNGTSRLGVSLDVAKASGSAAKEVSPESVADLVDLEQELTSLQRGISQMERITPNEPTTSSTGGAGHPSLAKSASEDDPFGDSFIYVPSYSILPPPPDSGRNRHKPPNKTPDAVTSLDAMLSPPPGTSSSHGSASAGLQAADNDDDNWLQELDQQNDVFDTSKVVSSSGLGSVLAMAPLASSESTATPTQQLTEVAAGSGPLADLDIGLSTALGNEEQTSTILSLDAFTDLDPLGTGRTRPYVDKKYFFQELKNPPKKLLKELSSGSQAGLGLGLSLGQLDGLFPEDSTTISTTTTTATNITAGNPQQNSANTLTSTASTAASLGQLLSTVALNPDPLPAPISIPTSISHSITPSAELKLLLGHVTNPPNPTGHYYTTEPPTLNSLENPHPPADPVLLPRDTDPFSPTRKKSDPDPFQESDLFAKLDAFEFEAPPAVPAPSIPNLATETKANVFNGPLQVQLPPEKELQLQQPPSTVRNRPTASVSALPSGGALDVISSISNKKMPHLFGQARSFGKSGSDIGSSVNMRRLQESDSLSETEAAPEPPPRPDSTPYSEPPPLPPKKQFSDLVIRPSPANTTQPPTSGRYEYLNSNVTARRTASSVDAPPIPLPSRRVGRSDGCFPGPGRPRKPGHTEDDYLAPLGAPPPLLPPPSQGSSARARPQRQASLGRPQDIYENKAEILQAQAQAQAQAPEVAPSSNTLAPDITLTQLLTLGMDDLAIKLNVPASKLSTMTLVQLTAYLSEYLSSEKSQVHSQERRSSPANTAPAPASTAAVFKVNFDQQTSFVAKFDDTFGEDEPVMPSGSSDSTFVANFANFNDAPTPVPTVSPVVATVPSADRYAVFREIIDQELQQQQQETDLMGDLTPPPVDETQAKEISEGLEVNNVGAELPIDALDVKPAPKIDTKITEVVAQAKDRYAALRDIILVENLFDKPAIATDTQPEKEKDLLQDFPEFSDEFNEDHDLRQIMDHQNVQTHARDRHGLVDSRGFPTEPSSSALTVGDYDEDEDADAGGESSLDSNEKDAEPVSGQDQYEKLSTSTQQLDAAAPALEDVQQLQQQSLPPKQDQKFLSILTAPGGGTKDDIEIDELMHRAISNLSLDSRDRVSPATSSAAPSRGAPGLHTPSQFNDVSTSPIPLQKPGMGPSPVPSQLSAVSQLIDTATKQMMGDKDREKQSWATFDSPKAKGKARLTLPPPPPPASNTSQPDTVESPCSSDPRDDGWSKQQRRWAKKERQQTSSSSRDLSPWDDETPEYLKRRQLAAAQMAHPHQPPMQAPPQHTDRHGYYMRHARRMNSCDEDYDYDGEFVARRDQPQHQQQQRKFKHGLSRSRDNFELESPSWYHHPAHHTWSPQEIEQVRVRSFDRTAYERSSYGPPPPIYDKRGQLRGKYRGDHRDRERERDRDREYRDYARPSYDFDYENVYEERGGRSPLAYKPGRGGGDYLYDRERDRDRERDRKSFDRESLESYESATRRRRSFGSGNDVYGSLDSRDDYRGDRERDRERDREQMKTRSLRKPTTTSGKLRISGDIDYEQDSEQDFQQRSGVRSLQRPNQLGGDVVLPSNAVVGPQRLRKSSGSSPWDGEEPALPGQKSWKRPASAAETERRLAESRRAVALGQTPSDGEKERRFRKKTRARSAKDLATVGAPSASTSAPSRSSYGRGIRDNYDYICPGQRNDDDDDDDEDYVDDEPPTDEDKFERLNRRRHEMHQRMLESERRQMERHQPPSLAKLPGQNRTRGVVANSDYGFVDSYEQTPTPTPRSNASSTGPGGLMMSGGESSAGVTSSKFNFDDGFESDFNQSSPPPAPAGTASSCNSTPAGPVSANANNGGSKSLFRFSNDFSDREKREQFEMDTPPTSTPPITQKLRFDDNVKVSQFDDAAFEDDFAKASFDFEKEQAGSATAGAGGSGAMSRKQNMRTSKLQQRQELIKKSESVNIFAKKQEDPFEDDEFFKSPDQEQAMDQHNDDTEGGKFQWSEDANFAKFDENM
The following text describes a protein:
Function:
Subunit 8, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (By similarity).
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MPQLDTSTWLIMISSMILTLFITFHLKVSKHYFPTNPEPKHTLLLKNSAPWEEKWTKIYSPLSLPLQ
The following text describes a protein:
Function:
Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex. Component of the retriever complex, which is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retriever and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling.
Subcellular Localization:
Endosome.
Sequence:
MAGLLDLRLKKANKIYSEGEVLAGVIVIQTKTEFQHQGITLVAEGSVNLQLSSKSVGHFEAFYNSIKPIPLLSVTLNAAKPGKIPAGKTEIPFEVPLKAKLNKTLYETYHGVFVNVQYTLKAQAKRSLLAKDLVKTIEFIIEYKDQKVKAEPKPVPFTVTPQSLQNVKDKTALPNFIIKGRLDSASCCIKNPLTGHVIIESCNAPIKSVEIQLVRVETCGCAEGYARDATEIQNIQIGEGNVCRGLTIPMYMVFPRLFTCPTLATSNFKVEFEINLVVVLLDDHLITENFPIILTRF
The following text describes a protein:
Function:
Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNVSILFDNFSMYMDGFYHTLLASVIALAGSFVLGVAVAVMRITVFKPLQWLGTAYVEFIRNIPLLLITFVFYFGLPNAGLRLDGFQAGTVALTIYTSAFIAEAIRAGIQSVSKGQMEAARSSGFTYSQAMLHIILPQAIKIVIPPLGNQFLNLVKNSSILGVVAGLDLMYQADLVSSSTLVVFDVYIFVALFYLVLTIPLSIGVNYLEKRLEKSY
The following text describes a protein:
Function:
Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MDHENLMKYLEEFRSIRFQPDFQKVDAERNVRYCEITDFPISNISFELLETGVSQQWRNCDQNLFNEYLKTYKNGGYSQFEDLLFKIWGYSEEKERFDLPALKSFYRKMSEIVGEDEVLEKLARLVRITKSACEVLPEKIYRLVGDIESATFSHIQCASLIAWMFFSDTPRLSFIIILQKTTCVAVEKLKFLFTYFDKMSIDPPIGAVSFRKMRITHKQYLENWKLRETNLLPDVQVFDKMSIEETALCTQIDFANKRLGGGVLKGGAVQEEIRFMMCPEMMVAILLNDVTQDLEAISIVGAYVFSSYTGYSNTLKWAKITPKHSAQNNNSFRDQFGRLQTETVAIDAVRNAGTPLECLLNQLTTEKLTREVRKAAIGFLSAGDGFSKIPVVSGWWGCGAFRGNKPLKFLIQVIACGISDRPLQFCTFGDTELAKKCEEMMTLFRNNNVRTGQLFLIINSIGPPLNYSEQYVFDAIRAKINSTKA
The following text describes a protein:
Function:
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.
Sequence:
MFRVAVPEGYTALVRGPAAVRCQELCKVFGGAFFYFVVSPHKQYPVEGPAIMELESGAIILIRGRAVPPDWGHELEGIAALVGPTDSGKSSLSTYLLNTHVAKGKRVCVIDADVGQSDIGPPGFVAYSCTSAPTPHISELEPHDAYYVGVTNLQGAEELLIAGVAWALKRAMSQYPHLILINTPGWTTGRGLQLLRALKDATGAKIINLGEKILPGLVASRPAHVYPRGPQERRELRNYAYRRHIKLAERLQAEPEKLANCNWDKGLDCPWGRYVPGDVPEPQRKGREHLVPPHYLRHLFAALYKNGRLAGYGIVEKFEPKITLYATTAEFDEIWIGKIRIDPQTLEELEPLP
The following text describes a protein:
Function:
Displays ATPase and GTPase activities.
Sequence:
MIVSGLSGSGKSVALKTFEDLDYYCSDNLPVELLPDFVRSRLRGNPLGDQRLAVGIDVRSRSDLTQLAQWRQAAQEYGIEARLLFFEASDEALLKRYADTRRRHPLSQLGLALPEAITRERELTAPLRAQADAIIDTSALNVHQLRRRVVTEFALGNSDRLSLLFESFAYKRGVPAEADFVFDARVLPNPHWDPELRPLTGRDAGVRDYLDKEPDVIRYSAQIVDLLDTWLPRLRNDTRSYVTIAFGCTGGKHRSVYLAERMARHAREQGWPEVATFHREQD
The following text describes a protein:
Function:
Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
Subcellular Localization:
Nucleus.
Sequence:
MEQLLRRELKTWQKAFKAQHGRDPTKRDILADAAIAGTYDTWQAVGGDAKAKCKPVSSGRSSTASSSKQRLTEGDRQDVFKTPSKRRSSVRADAVNGTSSRTPLRTPTKSSAIAAATTPGKSRNPFASPSKGTPPDTVSPARSLIEVEITPTRRSPLLDTLSRRSQFTPTKSPCHRQQFIASSPSKLRTTLEASVVLRRTPTKTARTRADNDDAALNAALVAYTPRTKARKRLRGEDVPPTPVAARRVVSGSSVGATRTDPRRIQRRLGVFGFGSNRKVQENRSVTMPSSASVFSRARSIVPGNDQDVDLRNESPSRVVRSLGRASSSAKGFRPLFASPSGNHAPQNVLDIAPRAAAAVGKRNVDQQLEDDADAIMDDDSASPVGGLFAAQVAQRRRARDSASPCKPMMGAALIKKHKVRAAIQLPSSSDMDDDEEDLPPNATYASSSPTPYHRGVDASSSPHTEVTVPSSTIRASTDRSYLSKQKAVETPISGPSRMLIAASATPPADVVGEAEQWRKVQQVELSDEDEPASQNGIKSAVKKVISITPYQRYGTLRTASSRFTADAEFDQDESIYTLPTSTTKGEMYAVDQIHDSSDSDSTDAHTSLAGLKLSPVRHAPSTRANRAQRHHLLNSIFDPTAKRKLKTTFNPEARFGPLEPSASTPAFDSDDDLDHQHDHHSHTNPNPPIASTLDDDNDDDDWQQEVDQDFTFLDLEIELQDVA
The following text describes a protein:
Function:
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib (By similarity).
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MTTWGLLFLLWPATTDTQACPRPCTCQSLETMGLKVNCEGQGLTALPVIPAHTRQLLLANNSLRSVPPGAFDHLPQLWDLDVTHNPWHCDCSLTYLRLWLEDHMPEALMHVYCASPDLATRRPLGQLTGYELGSCGWKLPPSWAYPGVWWDVSLVAVAVLGLILLAGLLNTFTESRN
The following text describes a protein:
Function:
ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaL-ADP is converted to DhaL-ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone binds to DhaK.
Sequence:
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHAGFIGKGMLDAAVCGDIFASPSQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLASEDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAGAAAELGFSLEKVKSIAEKAVSNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKVATADELAKKIVDSILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSIDMEGASVSIMKLDDELKELLSKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETCECHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSHAGDGDFGMSVAKGFKQLKREWKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAQMMQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAVKGAKMTEEIVARMGRAGTVGERSIGYPDAGAYGLGVIFTEISNSLK
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MSKAKRAGLRENGDGGMTGVDDTALASAIGNGEDLAPFIRAAFEVGKPETLIHQLKSFVKKKEVEIEDLCKLHYSEFIRAVDELRYVLVDADELKSGLAEENRQLQEIGDTLLRMLDALIQSHGTKKNIMQAIESLKMCTAVVDLCMRVNENVMNDSYYPALKALDIMERDFLPVLHARALRQLLERQIPVCRAHIERKVNKEFNDWLVHIRSASREIGQLSIGQASSARQREEELRGRQRQAEEQSRSGSKELVYMLEMEDLDEDDSQLKFDLTPVYRAYHINTCLGMQDQFREHYFKNRQLQLNSDLQISTTQSFLESHQSYFAQLAGFFIVEDRVLRSAGGLMSSARTEQLWESAISKVTVVMEDQFSRMQDANHLLLVKDYVSLLGATLRRHGYQVGPLLEVLDTMRDKYHELLLADCRYRINDVLANDKSERMMMKKEYEYNMNVLAFHLQSVDVMPAFPYIAPFSATVPDCCRIVRSFIEDSVSFLAYGGHIDYYDLVKRYLDKLLVTVLNEALLRLVRSPTLGVSHAMQIAANMTVLETACDYFAQHAAKLCGIPTRLVEGPHGALSAQSVLRNSQAVAHDTMIKLVKSKVDEVMNSTLNINWSPDEPPTIANDYLNDVYIYLQTIAETSQEILPPTAFYKVISGVLEHISRRIMETFLSEDVKRFNIYAVMGIEADLMLLEGFADDKYRTSVQDRVPGVQPLKSFLAEARQTVNLFMATQPDLYLNPVIRERNYGALDPKNIIIIGEKFKDLPEKLFGRGGKVAPKKKLIDALIKRLKNEA
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MVVESTSMATKIGIDEDVEVELELCLSLGGPFKKSDKAIIMRCANDIGVDLNDGTTTYEVKETGKKREAKQQQRSRGEGGECKRIRTECKEATNGVDLGLSFGDMGNGYGSGRYKQNSKDVTIGSPISSTSDVSDPSSSPCQEGGTSVLGENPDQTKPVRSPVNNTLTGTEETRITDGPNDAVVKESQECSNSIAKEAGKPPKPRPNSNGINGGLLPFAKMPFVTSTGNGPDGKTVNGFLYRYSKSEISIICVCHGTSFSPAEFIIHAGGTHVSHPLRHITVVPSTF
The following text describes a protein:
Function:
Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Subcellular Localization:
Secreted.
Sequence:
MSTKYRLSILALLLAFFSCAKAIDEKASHLRGDPINIAMLRKSGDDSVIEDFYSRELVCRVDMIGLRGEYYFNSSPSDAQTVCATYLLGESNDLVEIEFTQFNVDCNDPANILQFFDGWTMGVGQFPGDDDHPLPITERVINVCDQRQRVYRSHQNGAMITFRLGQPNASFRIAFRLINNPEPCNVIAPEPTGAHTLRNFGYERNCSFSIIYPTDVTIMEMSIGSEENDGTRLRCHDGLDYVELMEGNSLNMDTMRSETSLCGQVGNIVRQHGDGNPLNPNNQIVPGSPLCDARSVSMPLMCHNSVVRLVSSNQYENHVSFRFNQMPITRSACPEEEVV
The following text describes a protein:
Function:
Acyl-protein synthetase activates tetradecanoic acid. It is a component of the fatty acid reductase complex responsible for converting tetradecanoic acid to the aldehyde which serves as substrate in the luciferase-catalyzed reaction.
Sequence:
MTVHTEYKRNQIIASSEIDDLIFMTKPQEWSFEEQKEIRDKLVREAFYFHYNRNEEYRNYCINQHVSDNLHTIDEIPVFPTSVFKYKKLHTVTAEDIENWYTSSGTRGVKSHIARDRLSIERLLGSVNFGMKYVGDWFEHQMELINLGPDRFNTNNIWFKYVMSLVELLYPTEFTVDNDKIDFEKTVKHLFRIKNSKKDICLIGPPFFVYLLCQYMKENNIEFKGGDRVHIITGGGWKSNQNDSLDRADFNQLLMDTFQLDKINQIRDTFNQVELNTCFFEDEFQRKHVPPWVYARALDPETLKPVADGEIGLLSYMDASSTAYPAFIVTDDIGIVKEIREPDPYPGVTVEIVRRLNTRAQKGCALSMANVIQKNIKD
The following text describes a protein:
Function:
UDP-glycosyltransferase that glucosylates coniferyl aldehyde to form coniferyl aldehyde 4-O-glucoside. Glucosylates sinapyl aldehyde to form sinapyl aldehyde 4-O-glucoside. Is not active in presence of coniferyl alcohol or sinapyl alcohol. Can glucosylate the phytotoxic xenobiotic compound 2,4,5-trichlorophenol (TCP).
Subcellular Localization:
Nucleus. Note=Colocalizes with SIS8 in the nucleus.
Sequence:
MKITKPHVAMFASPGMGHIIPVIELGKRLAGSHGFDVTIFVLETDAASAQSQFLNSPGCDAALVDIVGLPTPDISGLVDPSAFFGIKLLVMMRETIPTIRSKIEEMQHKPTALIVDLFGLDAIPLGGEFNMLTYIFIASNARFLAVALFFPTLDKDMEEEHIIKKQPMVMPGCEPVRFEDTLETFLDPNSQLYREFVPFGSVFPTCDGIIVNTWDDMEPKTLKSLQDPKLLGRIAGVPVYPIGPLSRPVDPSKTNHPVLDWLNKQPDESVLYISFGSGGSLSAKQLTELAWGLEMSQQRFVWVVRPPVDGSACSAYLSANSGKIRDGTPDYLPEGFVSRTHERGFMVSSWAPQAEILAHQAVGGFLTHCGWNSILESVVGGVPMIAWPLFAEQMMNATLLNEELGVAVRSKKLPSEGVITRAEIEALVRKIMVEEEGAEMRKKIKKLKETAAESLSCDGGVAHESLSRIADESEHLLERVRCMARGA
The following text describes a protein:
Function:
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity). Required for the translocation of a variety of enzymes across the outer membrane.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein.
Sequence:
MIPRRSSDITIKTRSDVLPFSGASSRWLQRYAPALLAVALIIAMSISLAWQAAGWLRLQRSPVAVAASPVSHESIRSDPTRLARLFGTSAQDPNAPPPATNLDLVLKGSFVQSDPKLSSAIIQRQGDKPHRYAVGGEISDGVKLHAVYRDRVELQRGGRLESLPFPHRSGGLLASADDITSENDSIEQLQSLQDENAAALRERLDALRQQMEATPIAEPAEEDSSEPTTTPTESD