lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
Sequence:
MELLDRALEIIRTYPLCDSCLGRLFAQMGYGLENFERGRAIKTLLHMKLVDEYRKGRDVLNDLLALAKIHKPTSRFLTSLGINVDEAACYICGGLLKDVEKYAKDVLPLLEGVEFRTFEVGTTVPKDVVERESEVVKRFLITSGESVKHEINRRIGKELLKHLTGKRVDKLRPNIVVRVDLITGKASVERNPLLIEGVYLKLSRRVSQAKKFGDVKSTLWDKLVYIREVFGGKEHVIHVSGREDSDARMLGTGRPLVVEVKQPIKYDGAIPPFRDGDIIFTPIGFTNREEVRRLKEKAKTDIKLYRALVLSERPLTVEELNKIGELSGKTIIQYTPRRIKRISPRKKRVRMVYELAWRQISPRVFELYVRCQGGLYVKEFIHGDGGRTTPSVSEILNTHLEVLELDVLSVE
The following text describes a protein:
Function:
Produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MALLKISVVVPEGEVYTGEVKSVVLPGVEGEFGVLYGHSNMITLLQAGVIEIETENQKEHIAINWGYAEVTNERVDILADGAVFIKKESDDRDDAISRAKKLLEDASSDRLAVSSVLAKIESL
The following text describes a protein:
Function:
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Subcellular Localization:
Nucleus, nucleoplasm.
Sequence:
MTMNETSAIPARQRENQFFEIGVVGRKTGFTVPRDVKKGDDGFEDMDAYFLSDGSIHLDEDNGDIEQDMPPVTRLQPTSPMAVNAASDEASHASSSDSSDKNPDIPSSPLLMNSRALRASRGSSGPLIVPIDHSAFQAEDEGTADKTKVDGNKLSIQPRKANRIVDFSRIKASPDRKKFEPRRSTELPSKIPSSTPKDDNVQESPAFPDENITALQKNVANFTSIKDSGGRDNLYIQTISKPRRSYVQNNKSEQTIKPSKQNKQKEEKKTISQGNKPNSRDEDSELSIDVPLSMLNRSLANNSQKNKKRTPNKPLQESSINSVKEGESNPVVKRKRGRPRKNKLEIGNSVQTSEATQVKGAKKPAIRNAKKMSNEKDDSLNSQSDSASGEFIKTIARNNLQEIKQVEREDTLVGVRRSKRTRIAPLAFWKNERVVYELHRDENRIPALPEVKQIIRVDDPSPSIRQGRKKRHAKRSGVEIKSNLEAKSNDVEEYDAFYKDEINCEVLSWNEQNPKASEERVVGYSLPSVNLQQISNQQLKFASLFKEEPSFAAGVVEMPAGAEKPVKPSKHNIMSFCILQGKIEVTVNATTFRMKKDGVFIVPRGNYYSIKNIGKEAVRLYYTHATDTLENKRRGIGDFPNER
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MGTVDYICDIREYLVHLPRLSNYQVNDTVLYQLWKVLFECLNQGRSKGIVDWKKLLRVYESPNWQNGVFQSIHLPAEWREKFLEEYTGTGEGVGNDHRGTSCNKLCQPTETVYYCFNCTKNPLYEICDECFDPTKHVGHQYTSKVVSRPEGKVCHCGDPSGLSNPEEGFECKSALNNLPRRTMSYEHDESLVSILAHVLDYIVDTMMQLKEWTNDDIFLTLPMTLEQQSEYYALQLYEKDCKIHIKDLAAKISRVLCKPLEYGIMMVEKLVRGEAFVILLESKDTQKLKTVKEIFTNEHIATHIKNKNEVFRENLVDELIRWIYELCYKRPNVQRKLALRVAMMSTWNSKLLGMTLRSQATMVPYWSKIYLLGNFTVQYSQRTSFPWCSPWSFDEAKNEQHDPRVLEIMKEYDKRLAEVVPDNSTAKYQPLNGSRFQYLITDGTAVMSKVSRYRMMKVICSMFTIIDDSKKCLAAQYLDVYCAVLYNTVASESTDYKISLMNMLSQYIFQNPQIANMIITKAPGFIQRALQFAFALLSFAPATLINCPPIPLSYDFKLPDDSIKSKRSVVCFKDIYLIMSTNTVPESVFQNQELTSVIIKCFASFNNILPLRREAKEHVEFENFDFSSYYFLFSSILVMVDGFVRNVCLIKDPRRRREVVYDLLDRSISLEIKMLSCFRNSIPFSDSLWDSSDAEPQVKMVRETIYNVTSNIISFQVGIDTQNFFNPMSYFFKFVLQWSQCGRYETLPEELKGYINLVSFFKENKKLIFMAESALSTLVLIAQINSGFWVRNGAPIIHQLRMYTKYSMREFTYFSDIFNLQLAMSLSPPNDFMVTFISRWHLKNWTEGVPIDDYPDKDVTSSMVDQCLLLLIQLLSEVRSLTMSSSVEGFEKTMRSEIIHALCFHNCSHSNLMNVIPEHVTKHPAFDLYLEHLANYTPPIGITDHGVYTLKEEYMNEVDPYFVGFSATKRYEAEKLMRSRMESNQLIPYMDTFVPAKNVIMELQFTPFSGLYQITSTDIFGIFIKSTLEHIAKFKYEAMLSKVAHIIHLCFINNLNGFVNVFWREYSFDETALSFYNSIGSLLFSFLLDEDFCSDHGKIREIFSLLQREAPHVDVDGYLNEQTPNYDPQIWKSRSRELKKGEDEYEKKRLAKRKRDRLLRKLAKQQQQFMENNNVTPEDIDSRETTIDGSFSAIGWEYPDDTCVFCKMPRVENDTFVYFTHFEQNTVDKYTDFGKLNLLQSLYTSAKPQPLFPSPGSTSICHVVKACGHGSHFSCMERHMKASRNAHNHMTKNVPNGLGFSLLFCPLCNSLVNSFIPRLSDVNTRCDEELFAGTHENKYSMSSEELDTLCLKSLIIFCSLTVQSKFSRLPDIYTLFCSVIANTISNIELITRSGDTTIPITKRLTNQQLLTLRLLTEMKIYILERKLFSHQTGKITGIPIPAVREYDDWAAFNVEFLHSNLLLDACRYLNPITRKGYPLSAFVYASIKRKLHQIFIALSTTLVEDSDCMIDGDQNVMDWDVDDIDSGQEGADSVLGVVLTYIVALSTAISIDRSQLNRVAKWKVLLYNVTEKALTVFLRRFLMLIFAEYPITKRECNTIELELSSLLSYFGVPQLDSILTDFRVNDLPLTKATIKEASKGPNIQSYAQKVYSLRVESPYGSPLIPLPHRLSDLLSDEEEQLQYRINRHEVAMCLFCGTKVFIQNASMLHNFMIGECTNHYSNECTQTAVYGCFLLVRSNTVYLAYGDRGTFFKAPYVNKHGEVDEDYKYGTPVFLDEKLYSHLGNDIVLGGKIPHLVHRLTENMSDVGGWESM
The following text describes a protein:
Function:
Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex. May be involved in lateral roots and nodules formation.
Subcellular Localization:
Cell membrane. Endomembrane system; Multi-pass membrane protein.
Sequence:
MFNVETRYSNYLVLGYKGTCVAGFLIFLTLYSTSIAYVLTTTTSLSMLIHFTCNAILGSNCCHKKGHEAPYKYGGNLYMALFGLVQIVMSFIPDLHNMAWVSVVAVLMSFTYSFIGLGLGIATVIIFQALGDIAFAYPYSILLLEIQDTLQSPPPENQTMQSSTCAGLAFLSLSGTTNDTPCCGCLHHSSLGGRISGCLDTLQLGKLCVVKRSFISFMCSNLGVKSCGPSHLLCKFL
The following text describes a protein:
Function:
ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase (HEM1), thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. Up-regulates heme biosynthesis.
Miscellaneous:
MISCELLANEOUS: Present with 10900 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MLKSASQNFFRAYSSRIGRYAATASGKLAQSRLSNIPTPKALKKFLDEYIVGQEIGKKVLSVAVYNHYLRINDKQKKGELQRQRELMEREKIADDRDEPIFSGNSESKAGWRNLQRQFNLAGREVDEDLELSKSNVLVVGPSGSGKTLLATTLAKILNVPIAITDCTQLTQAGYIGEDVEVCIERLLVNAEFDVARAEKGIIVLDEIDKLAKPAASIGTKDVSGEGVQQSLLKIIEGHKVEITVKRPVKHDIDGQKNQTTTKKDEVFVVDTSNILFMIMGAFVGLDKHIVKRIEDMKKIQKAGESVESSNSKEVEKERAKKFRFSNTLEQVELDNGKKVCALDLTTPTDLVSFGLIPELIGRVPIITALQPLQRDDLFHILKEPKNALLDQYEYIFKQFGVRLCVTQKALKKVAQFALKEGTGARGLRGIMERLLLNVNYDCPGSNIAYVLIDEATVDSLQETEHSLASQVDVKYYSGDEKDSLIRDVSEEDKKLGVMLEKELGHSANIHTPTIPKRSLT
The following text describes a protein:
Function:
Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of Tim9b/Tim10b from the cytoplasm into the mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across the mitochondrial outer membrane (By similarity).
Sequence:
MDSNLRNLKDFFTLYNKVTELCFSRCVDNLSQRDLGGHEDLCVDRCVTKFARFNQNMMKVYVDVQTTINAKRMEEMEENARKAEQQQREQEKERLKEAAATAVLTPVQPPVAGNLSM
The following text describes a protein:
Function:
Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system.
Subcellular Localization:
Nucleus.
Sequence:
MPRAFLVKKPCVSTCKRNWSELPDEERGEIYVPVSLGFCPPQPYQEPEPSVAEPSSCPLVLDMSLRDSSYGVVPGPCVVAQLPSEDISHLAEPQNRDHGFLRTKMKVTLGDGPSGDLFTCHICQKAFTYQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFDLKRHVRTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEECGCTSESQEGHVLHLKEHHPDSPLLRKTSKKVAVALQNTVTSLLQSNHHL
The following text describes a protein:
Function:
Component of an histone acetyltransferase complex.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MLNSQTFNDALAAVSFLENYLDNMDYLPSEVQRHITIFREIEYQCKEVMTKLLVEGETYKSSSDVLIKKQAINQIKKLLIRQKDLGDQKLEILSTIYELVENNSRSLEDSMANLESVQGLPSHVKNEEKSFFPSVAPSASMATSSAGCSSHQKSAADNNNFNTTHNTNNSTNNNSSSSNNSHATTLSTRASTSSNFKPDDKQDNGKTKRHRQAKRSANHESYASAMKEEEKRDEEEKSRKKKTRREKMDKSSLMMAANNSHLVKIIGNIDPNEPLYCLCREVSYGEMIGCDNESCEVEWFHFHCVNLTHKPKGKWFCPSCRGDRQSVLNPELLEQRKAKKNAVMAIAAAAASNNNATSD
The following text describes a protein:
Function:
Male determiner protein (M-factor) that controls male somatic sexual differentiation. Acts as a dominant factor that regulates the mRNA splicing of doublesex (dsx) or fruitless (fru) transcripts and promotes expression of male splice forms of dsx and fru.
Sequence:
MCKKRNAEINAEFDIIKKYCIYIGNIPFFASKNDVVVKFAEYGETCNIYMQSNKPHCDVKPAIVRYRSRKSVDKSLCLNNSKFGNTILIVLPLSLPYSRYLLTYDTCIVVYINDKNSCKTSMAELYDEFQKIGDIQNMFKTTNNMIYINFESEKSMQLSLATKPFLINNNIFKIKKVERNINMCGLNSESQDFSTNLKKKLLYNRSIGIFGLPSNATEERIAQIFSRFGDIQKITLICDVVGNSKQYGFIYYKKRTSANAAKVIMDGENFEGNKISVRFVPEKKVFKN
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSSEGERGHRHHRKHRHDDTDESVDEIENSDHEEKPSKHSKHDSDNEEKQKEKKSSSKNDDATKAYEYDPDFHGAVPERKCTDCCMLIIFNIFLAGMIALFAYSLTRSNPKYLYIPTDYRNLLCGYDNSKLKVDNSSLLPNLEDRPYLFWVRPGKKGYVRSFCVKECPTEGLFSDAFLANLIDQELHNDTIGGEKDEKCHDSNVTKRTVPGYKVPENSSDVSYYCAYATKQVLKRCMPTTDALPDTEVNLSDYTKIFKESLSAQTLLTAFSDIFNAKWYIAIFTAASLVLAFIWIILLRFTAAFFVWFTVLLAFAVSALITALCYGMKTDYFKMAGKTQAYTLGLISKDLNAKIFNVLFWVCIAWDIVFTLIFLFLCDRIRISVNIIKIVSKVFGQVKTLFIFPIFIYILMFIWWIYIIGVAIVIYGAGTPVFIYDSNIGNMVEYKYDQILKYLSIYHFFGFLWVSVFISDLGEMALAGVFAAWYFNKDPRREHMGKIPVLRSFGRALRYHMGSLATGSLIIAICKFIRYCIEYIQLKTKDAQSTFVKWIVRCLICCFKCLEKFLKYINRNCYILIAIHGYNFFQGCKHAFELITRNIVRVVTINWVGDFTLFLGRVFISGIATAVSLYIFMKKEDIEFYCVPAAVVFVLSFIVSGVFTELFEMGIDSMFLCFMEDCERNEGHEMYTPEELRSWIHKDKENSNEENQS
The following text describes a protein:
Function:
Component of the BUR kinase complex involved in transcription regulation. This complex phosphorylates 'Ser-120' of the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B, the localization of the PAF1 complex to the chromatin, and the silencing of telomeric-associated genes. Also required for histone H3 'Lys-4' trimethylation. May phosphorylate the 'Ser-5' of the RBP1 carboxy-terminal domain (CTD) repeats. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase. Also required for vegetative growth itself. The kinase activity of the complex requires the presence of BUR2. Overexpression of BUR2 interferes with mitotic chromosome segregation.
Miscellaneous:
MISCELLANEOUS: Present with 2910 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSATSSSGDVKKFQAVPKPTSNASPPPASSGFNARTLWPDLIETPENQWVFECKDIIEKIGTNGPIAVEIKKNMEKCLMYFYTLKKKLNLFDHTYTASCILFYRYWFIYGIPTAITECIHISQGILVTACKTMENNRPIEAYIKATCEFLMQNIPSLKSRTNIDKLKWEFRDKLVTNEKKILCLFGFDLNISNPKELIEEVFSGYYRFNRDHNLPENFKKAFPKILQESRNFMVQAVTQPVSLLCDGYTFIVLSLIYCGLEYKKLVDKDFRYPKNFFKDRFPIEVTPENFANIFTDYKLLEENFFNLKSNKGAKLQIDSSMIDSVIDESGDVENEVSEISDPFNYELIKSGEVKEEFLNHIETRVKDLLDKAKQESMKRKAKDPIRTPDAKKPKI
The following text describes a protein:
Function:
Forms chloride channels.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MTVSYNLDVSSASIFSFLRLQLRWKGSIWKYLLKELFFFILAFGVVSGVYRSNLIIGENTRKIWDNFAALFDQTMEFIPLTFMLGFFVTIIVRRWNDIFANLGWVDNTAITIANYIRGTDDRTRMIRRNVIRYMVLTQVLVFRDISLQVRRRFPTLESIVLAGFMLEHEKEMLCNVACKYSKYFVPIQWSTGLLVEARTEGKIAADLLMNEIGKNIIEFRKGLALLSNYDWVPIPLAYPQVVFLAVRSYFFMALIARQSVLLDGKDPEQPSILYPIVPFVMSVLQFIFVVGWMKVAESMINPLGEDDDDFECNFLLDRNLAIGLIIVDDCYNQIPTVEKDVFWCSDVEPLYSVDTAMIPKNPQIGSAANYEVKTDEEEVMMMPHMDDVDMFDFESTNHLIPRKTFSVISIQRPFGSRASLASRKRSMMFDQLRGRMAKKQNRNNMFQNSASQATLHYNFESQAPSEINLSTLEMTAPKRKTSTGKLGSTSESNHCFLNVAEEQHKLSAEVLPIVLEEDEERSKMLEKDKTKFSRVIGVNREQNTGNAPWCGDTIPSKRRTRESGSRSGRSKSSSRFSTFIQGGGGGQKALRSARSTSRGRRSNSKRSRRSSRSRSRSVSTARESSRRRVRRASKASRCDRSRSRNRSSSRRPSSRRSARRSVSRLSNRRTTPKVSRSKWVT
The following text describes a protein:
Function:
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
Subcellular Localization:
Nucleus.
Sequence:
MVGIREQLLLSDTKKPKRCNPQEKTQQSLRKVRILVNDPYATDDSSSDEGETKTRRIVRVVNFPPLVESAAPPRVEPTSVSSSQDSTKTTSKKAAAAGASRPRLSKKPVGVRQRKWGKWAAEIRHPITKNRTWLGTFETEEAAHQAYKDKRKEYDALLATSNDSASVSETSQCSRSSPLEQDTSASTPALKEEIKITTTTAGVDSSSKEVLFGFNFAELPIPDLGFFAEEGQMGDLGFFTEDHDQLNLDCLFTDDQFDDFSMLWFEDSGPSELPDWDFPDVEFESSFFFADQHIPLKSFVA
The following text describes a protein:
Function:
Participates in DNA repair and in chromosomal DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MGASATLKKVQRKFKLRSLTLNREALNEVTTFLTNFSEEQEDEYLDLLLNQIEQTTLKKSVLDKEVVRPIVELLLEADAAIDTGKSCSNEGALRIVDAFLVPKLSYDPIKKTFYEYTGNLPIHGDASSKVALYRERYQLLNQRLLRNSDFSRPAFDTDITRSGGEVHTCGFPPLEDGNASLAVHTGLDFFGAGYLTPEETARLVELEKKAVNDMFVILSDVWLDNEETMEKLAAVLDGYENVEVVPSLFVFMGNFCSRPCNLAFNSYSSLRSQFAKFGEMIAAHPRLKEGSRFLFIPGPEDAGPSTVLPRCALPKYLTDELLNHVPNAIFSSNPCRIRFYTQEIVFFRRDLLYRMRRSCLIPPSKDETDDPFGHLVATITHQSHLCPLPLTVQPILWNYDHCLRLYPAPHTIVLADNCKQQVFKQEIRKNNKTLQIITCFNPGSFSCDSTFVAYRPCNQEVELSALPGPLLFCMAQPVPWKVEDPWPTLCRL
The following text describes a protein:
Function:
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPIPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQPENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVVSAGSAGVTHSPMSQTLPWDLWTTSTDLVQPTDSSKSLSLCNLIMEETPDSGLTEEIQRSQIDLGAFIWGPDASTDSVSQEITQGGSQEDSACLSEAEQGTGLFTGLLPSADWRTEQGDHVLGPAPPCENEQLSPKPRPEAEFAVAACMEMEQPYDLPESQMPAMETGGLVTESQEDVKRSEDEEEEKQKTEDSLWAGVETCEKVDTGAVDIKALEGIEEFGEKACESTGNRVVHLLKMAGKSNQETSEINEEESRKDLRARCKENSNGKYFEKADILEKVMEGVDMAEEFSDRDQGLDEGIQVVINNCEITEGSGAETANHTGLLNLPFQTDSVSNIEDVSPEEWVFARKDIKKNLLEPPNHDLIYHSASAQGGADAEEIQCEPVLCDSGGDRDENQAVVLSVTHEVAAQSRTDLNCFLGTDANRRDWCLCKVEDSLIEGSESTVTGNCSHTINLPRIAKTDFRGTDPGQVWQPNLELAVNNMDLLEFSGKPDGQASGFASWLESTNHWPIRDTGGLDNCWEHLDIVESKKGLEVDLVADVCGERAIASCWEQSRETARPLVLGTSQNASTESSASPQDHDINNSDLSEDEIANQRYGLLYQEIEADKEEASAGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPPAAATPAVGLEAGLDTQAEEPAEGAVIIPGTEADVTVGISMPAAEGAPVEEAETEKAALPAGEGASLEEARIDAEAAEAVDSDRSQPEETAAAAPPEKVIPSVIIEPASNNEGEGEHEITIGAESKEATDAAAPPVSTSVTPELALEQEAGEDSQPAPAALSASEVSQEVPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
The following text describes a protein:
Function:
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleaves pre-rRNA sequences.
Subcellular Localization:
Nucleus.
Sequence:
MVRVKYRYLVVNFLYPEPVAKSKTPLPDLVQIHAPTPDAFHAGTLMRLIREGVEDLYGDYGAGMVSTGLKVNYWSPSTSTAIIRCPRDHYEMVWAALTYTTRLPKPADLPVVMRVVRVSGTIKKAEEEVIRRSQLIIKRARAAETKTPMLESVEKVADEARKSENNILAQVDAGSEDDDEDMSE
The following text describes a protein:
Function:
Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Catalyzes its own deactivation by removing the activating phosphoryl group.
Subcellular Localization:
Cytoplasm.
Domain:
Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
Sequence:
MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAIDFVTKPQLGIREGMLAYNEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGERVLPGHAYIAPGDRHMELSRSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAVGVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVSQQMLAKISAGQAIRI
The following text describes a protein:
Function:
Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes.
Subcellular Localization:
Nucleus.
Sequence:
MKLKLVIDSDSDDYRLFKTTISTVAQLRKTAVLRFTTDRLIVVSTPKTAASGAILSGDQGQLWCTIPRDIFTLYNVASIREQNAIAMECQCDSLVNVLRRYERCNHGPLTIKLQSTPEWNQVHTGIQQGEENKPMGNPICALSCAFTEHLGYEDSGKEVSHVFKVGVRLLYKSQDARIVEPMVNYTKLLMFQLPPVNGEYGSKFTSFVKRLDRYATLNHLMIYGDRNSDRSDEGRLRLLVQELDWKLDVQWRGPLEMIVQDDQPSAVPASEPGLVGNVRHLNAGTSMQIEDSEMDIEATDIGNVSTSRPSTSVSPQEQTSQVFIKAKDWKVCSKLYDSFEEVVLAISHDESCVLHCSLDRGTVDEHSTKSKERGQIIYYMARSKPL
The following text describes a protein:
Function:
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGNIWEYNGSALIGIKGXDCVALAADKRLGCSYQTLTIGNEERIFRLSQSCLLGLAGLQTDVLTTYRQIRMKSNLYHLQEDREIRPRATAKMISSFLYKHRFGPYFISPIIAGFEADGKPYLGAMDTIGCLDDCTNFQIAGTASDFLLGLCETHVKPDMSEDEILPLMEQIIRSATNRDAYSGWGAHVVVLRRDGTTSDIPISTRMD
The following text describes a protein:
Function:
Glycosyltransferase involved in the xylosylation of N-glycans. Possesses beta-1,2-xylosyltransferase activity, transferring xylose from UDP-xylose to the core beta-linked mannose of N-glycans. Beta-1,2-linked xylose residues on N-glycans are critical for seed germination and plant development and growth under conditions of abiotic stress.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MMPVRTYHHHHHHNNSNNHRLRRIIPRVLLAVFAIYAVSFAAYLLRHQSPHPHPHPAADPERDAVDAAGGGGGGGAVDRVRVEAPSSQKPWPRLPSFLPWTSASVRPPPKHSCEGYFGNGFSRLVDVLPARGGGGGGWFRCHHSETLRSSICEGGRVRLDPGLIAMSRGGEPLDQVMGRAEEEELPKYEPGALQVEAAAKRTGPLVEAGFLDAYVPTGGIGMHTMRSLLDSGRVVPPGELHCSQWVEEPTLLVTRFEYANLFHTITDWYSAYVSSRVTDLPNRPNVVFVDGHCKAQLEQTWEALFSNVTYVKNFSGPVCFRHAILSPLGYETALFKGLSESFSCEGASAESLREKPDHQKTARLSEFGEMILASFDLLRDDILSSKTSNGLNVLFVRREDYLAHPRHSGKVESRLSNEKEVYDAIEGWAKGQKCKINVINGLFAHMNMKEQLRAIQEASVVIGAHGAGLTHLVSATPDTKVLEIISSMYRRPHFALISHWKSLEYHAINLPGSYARVTDVINELSNILKGFGC
The following text describes a protein:
Function:
Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPases. May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. Also acts as a GEF for RAC1, inducing production of reactive oxygen species (ROS). Does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production. Required for EPB41L4B-mediated regulation of the circumferential actomyosin belt in epithelial cells.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane. Apical cell membrane. Note=In unactivated eosinophils, distributed around the cell periphery in the perimembranous region (By similarity). In activated eosinophils, relocates to the tip of the nucleopod, a membrane structure formed during activation when the nucleus moves to one end of the cell, and is also concentrated in membrane protrusions at the opposite end of the cell (By similarity). Localizes to the apical cell membrane in epithelial cells (By similarity).
Sequence:
MGSEPKPYAQPLDSAAAASTTKGSCGPRKPENPDFFSTVEDEQEDGFLRHLSESTEDFSLDMGALQGSEYLRDLGLGAPSDLHQSEVIMDPETHRQEARRESSHTSCEGASALPQRRSWERSRSCSGSCRRLSLDASTVDKGACLPRTLASLALNLSGNGQKIWTQGCLPVSGTPAPSSKECSSPEKRLRSKSVPVSCEISCMELASDSDVCTSPVQGLEPPVLECLEKDHVEPEHVLIVQQVLQELRQYHGARQRARMSTSPGGAHSNLTWFEFLSESEDGACKIEKPGKSTRVKRSLSSLRSRVTRQKEKGKSPAHLKDKTQDLPGKRECVNGHQLMRGTFSGHSSCPLCGEPLLNSASLKEHPRTTLLSDGSSPAPSRNVGMTISQKGGLQPTPSPAGSGVRLGPIAGDMDEADSVFLKLKQTADDSLSLTSSNAESVFIEDPYIASLRCEIESDAHEFEAESWSLSVDLAYAKKQKKEVVKRQDVLYELMQTEAHHVRTLKIMLKVYSRALQEELQFSGQAVSRLFPCADDLLDMHSHFLARLKERRQEFLEEGSDRNYVIQKIGDVLVQQFSGETGERMKEKYAVFCSGHNDAVGQYKLLLQQSKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTEDYKDLSQALSLIKDIISQVDAKVSEYEKDQRLKEIAAKTDQKSSGKLKNGLTFRKEDMLQQRQLHLEGALCWKSTSGRLKDVLAVLLTDVLLLLQEKDQKYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASMQGPEMYEMYTSSKEDRNIWMAHIRRAVESCPDEEEDVFSEAEEKKIAEARTMKLQEFQERLSLKDQLIAQSLLEKQQIYLEMAQLSGLEESAQNRGLFRGGGDPSETLRGEQILRSAMSEIEGIQSLICQRHLGSTSSQVEEGSVSAGLPRRAETFGGYDSVGSPSKGGSFKRKVSNSDLRPQDWQGPASSPDSRPCDNSAPSGCCEESPQAVEMPSTESLPTVLELELVHRVQTLSQLLLSLQAVIAQQDSYVEMQRTAIQEREKQFRLQSTRGNLLLEQERQRNFEKQREERAGVEKLQSQLRQEQQRWERERARQQQELELAGARLQEREGEARQMRQRLDQERTELERQRQAYQHDLERLREAQRAVDRERERLELLRRFKKQNTVPGALPPEVLAEAQPASHPPSFNGDGLEGHSAPAKAPGTQGSAMLHGTGPDNVERPEVARWDSAPPESRPAKSDVPIQLLSATNQIQRQTAVQQQIPTKLAASTKGGKEKGSKSRGSQRWESSASFDLKQQLLLSKFIGKDESASRNRRSLSPVLPAAHGSAPASDPCFPAPSPAPAATPPEAFKFGGTSLPPVSPASSLPTTPLATTDEVSKEDVIFF
The following text describes a protein:
Function:
Involved in exit from mitosis and pseudohyphal differentiation.
Subcellular Localization:
Nucleus.
Sequence:
MPNFQKPFSGSSDGNSVMNDLGNKVAIKVFDCRSAQDGSEEQNVNVTTNQMYLMFQSNNYNVPPPNYNTEDLGSQGPPTHAYYAPFQHPIHLQPPVPPVYKNNTYSATDQYSDSSFPNTSGHTPVIDSNYYNDALASIPTTTTGSTTMTTDNGNTIDSEEYIDNMEVFSSEENENIDNVKQTDLKSEKDSSLLSAASIVKKEQLSGFENFLPLSKTESPLVTADEIKSSLNLENIDNADSMSFKLKTSPIRKHFHVKPKRITRVRTGRVSHNIIEKKYRSNINDKIEQLRRTVPTLRVAYKKCNDLPITSRDLADLDGLEPATKLNKASILTKSIEYICHLERKCLQLSLANQHLSNDTRDSFVHLTEPSQPLSDNSSSEQVQKQTRSCQRQRQRQPRQQQPLHNIQYNIPHQNGLMSGTNNSHDMDFNNAGDF
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
Sequence:
MPPKQDNVQKLLAAEEKRNNLISDAKARKQQKVKQAKADAEREVASFRADKDREYDRYRAQQNGGADAENAELARETDRELEELKKLTAQRMDAVANMMVRLIVTVKE
The following text describes a protein:
Function:
Toxic component of a type I toxin-antitoxin (TA) system. When overexpressed kills cells within minutes; causes collapse of the transmembrane potential and arrest of respiration. Its toxic effect is probably neutralized by antisense antitoxin RNA SokC.
Miscellaneous:
MISCELLANEOUS: Interrupted by an IS186 element, which silences the locus in strain K12 MG1655.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein.
Domain:
The periplasmic portion confers toxicity; dimerization is not required for toxicity.
Sequence:
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE
The following text describes a protein:
Function:
Alpha-amylase that cleaves starch into oligosaccharides before internalization for degradation, the first step in starch degradation.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Sequence:
MNKHLHFLSLLWLSMLMAFMTACSDDKNITDPAPEPEPPVEGQWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHDEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSDSYTLKLGGYASVVFKLGN