lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10 (By similarity).
Subcellular Localization:
Nucleus speckle.
Sequence:
MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSPDKSRSKSKDHAEDKLQNNDSAGKAKSHSPSRHDSKSRSRSQERRAEEERRRSVSRARSQEKSRSQEKSLLKSRSRSRSRSRSRSKDKRKGRKRSRDESRSRSRSKSERSRKHSSKRDSKVSSSSSSSKKKKDTDHSRSPSRSVSKEREHAKAESGQRGSRAEGESEAPNPEPRARSRSTSKSKPNVPAESRSRSKSASKTRSRSKSPSRSASRSPSRSRSRSHSRS
The following text describes a protein:
Function:
Ets-related protein that functions as a negative regulator of photoreceptor development acting antagonistically to pnt and the proneural signal mediated by RAS. It acts upstream of SINA to inhibit R7 development.
Miscellaneous:
MISCELLANEOUS: 'Pokkuri' means 'dropping dead' in Japanese. Flies lacking aop result in the differentiation of supernumerary photoreceptors in the eye.
Subcellular Localization:
Nucleus. Note=In undifferentiated cells during the early stages of eye development.
Sequence:
MSKMKMLPVQLSLNSLNPGIWSDVLWRCPPAPSSQLAELKTQLPPSLPSDPRLWSREDVLVFLRFCVREFDLPKLDFDLFQMNGKALCLLTRADFGHRCPGAGDVLHNVLQMLIIESHMMQWHLPNSPVTPTSRYPLSPHSHPPTPTWPPLNAPPENSPFHSSAHSLAGHHFMAPNSVTLSPPPSVDSQASSPPQAPYQNGGATGAAPGSAGGSAPAAGGATNTSNPTSSSASSTGSNGSQPNIMPMKGISSASSNHSDSEEEYSETSGGVSKMPPAPLSYSTASPPGTPILKDIKPNWTQQLTNSFVNSWSQQQQQQQQQQAAAVAAVAAQAQQHQLQQQQQQQQLPQKLTLDNTAGPVVTPAGGSISAPTTPSYMYKAKREFFPENSEPNTNGRLLWDFLQQLLNDRNQKYSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRNPTELKNIKNISLLRQSTPANGNGGSPSMPQGSSQAPGSPAGQNWNPQQQSQQQQQSPQRPASRNGPMSLPAVAAVAAAAAAAYGPPPTSPLFMHAINGAFHYLSAAAAGPPPNSPALNTPSAVGGPDKFQFHPLKLENGSGSGSESAGEDLKPTDLSVSSKSTATSNEDCYPLIRNADGLTTIKLIRYNEHQVAASPAGQSPKHDDQQAGASNASSSPRPMDQASEQAQPVPMESDCNGGESEDSFRHMQQ
The following text describes a protein:
Function:
This protein is required for low-affinity potassium transport.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPTAKRTSSRASLALPFQLRLVHKKSWGHRLRDFISGFLKSCRPIAKYVFPNFIVVHYIYLITLSIIGSILLYPCKNTAFIDVLFLAAGASTQGGLATKSTNDFNLYQQIVVYVITLLSTPILIHGFLAFVRLYWFERYFDNIRDISKQNFKLRRTMTLQQRELSGSSGNAARSRSFKDNLFRGKFVSREDPRQSASDVPMDSPDTSALSSISPLNVSSSKEESSDTQSSPPNFSSKRQPSDVDPRDIYKSIMMLQKQQEKSNANSTDSFSSETNGPAFIVQERHERRAPHCSLKRHSVLPSSQELNKLAQTKSFQKLLGLRRDEGDHDYFDGAPHKYMVTKKKKISRTQSCNIPTYTASPSPKTSGQVVENHRNLAKSAPSSFVDEEMSFSPQESLNLQFQAHPPKPKRREGDIGHPFTRTMSTNYLSWQPTFGRNSVFIGLTKQQKEELGGVEYRALRLLCCILMVYYIGFNILAFVTIVPWACTRHHYSEIIRRNGVSPTWWGFFTAMSAFSNLGLSLTADSMVSFDTAPYPLIFMMFFIIIGNTGFPIMLRFIIWIMFKTSRDLSQFKESLGFLLDHPRRCFTLLFPSGPTWWLFTTLVVLNATDWILFIILDFNSAVVRQVAKGYRALMGLFQSVCTRTAGFNVVDLSKLHPSIQVSYMLMMYVSVLPLAISIRRTNVYEEQSLGLYDSGQDDENITHEDDIKETDHDGESEERDTVSTKSKPKKQSPKSFVGAHLRRQLSFDLWYLFLGLFIICICEGRKIEDVNKPDFNVFAILFEVVSAYGTVGLSLGYPNTNTSLSAQFTVLSKLVIIAMLIRGRNRGLPYTLDRAIMLPSDKLEQIDRLQDMKAKGKLLAKVGEDPMTTYVKKRSHKLKKIATKFWGKH
The following text describes a protein:
Function:
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MSHPALTQLRALRYFDAIPALEPHLLDWLLLEDSMTKRFEQQGKRVSVTLIREAFVGQSEVEEASGLLPSESRYWLREILLCADGEPWLAGRTVVPESTLCGPEQVLQHLGKTPLGRYLFTSSTLTRDFIEIGRDATLWGRRSRLRLSGKPLLLTELFLPASPLY
The following text describes a protein:
Function:
Catalyzes the deimination of arginine residues of proteins.
Subcellular Localization:
Cytoplasmic granule. Nucleus.
Sequence:
MAQGTLIRVAPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINTSPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKAASVSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLNSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP
The following text describes a protein:
Function:
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex to regulate dendritic spine distribution of the STRIPAK complex in hippocampal neurons.
Subcellular Localization:
Cell projection, dendritic spine. Cytoplasm, cell cortex.
Sequence:
MLKLCKVSMLDSPDASGPLLRTPAKDGYSVGTKPSPSTSTPSLLKNNRLLSQKQHPKEKGIMEFSKSDLMKLLGLLEAELQARDLVINSLKNERTKLLKPSKNHHRQYTLANPYTALVRDSEKAAGKGDSDEEKAKGADTKDVVASLHAVIEHHRKAEERLKNQVQTLKASHTKAVNELEDEKRRHAQDTAQGDDVTYMLEKERERLMQQVEFEKAQQSKLERECKRGQGRLIQERKRHAEFIKLMFDKHLLLAQQLGDTQQRAMEWETQAQAMRAEAQNASKLAAEERNKSVKMEAEMEKKLSDFDIEREQLLGRLQREEMRTRELREELEALKKSSKKSPELVNGRIANGSELNSNAKGSSSKSIVSSSDSKTSKGKETPGSVRKPAVLKPKASAKIYGAKGYKTPPQSDKSEASSSSSSSEDNNVTVSLSRVHSVSPAVPSPKSNPSESKKPSITSKPKPSTTNFSRGAGKDSRPLSPASSLDKLSGKASSASPSSGLSQKGTKIPSSSAMFANSSQLRKSAPTVAVVAPQPSKASNVTQEASKQQQHAKKSIDSTDSPKSDKSEPKSNPMSRPTTLASGDTSLKAKEPAGKVSQLRNTLTSPKDKDTRDKSPTRGYGGMNVKAAAAQLTSPVGKKVFNPVGSTPNKLNSSTPSEPSGTTQTKEAPASVSTNAVSDKVKPVVTSPSSTTPGKRNVSPRGRPPSLTRPTLCPSAWESPLHQAARQGDTATLCRLIEEQHDRTSPEKDGSTLIHAAAYGGQVDSIDLLVTLGEDPDTAQSEGLTPLHVASGEGHEGCVRFLSEHGCNPLSRDSQGWQPIHWAAASGHASCVRTLLDNGAKRDCITNIGWTPFHASARYGQMGSLHALLYHTPTREQTDLQMLSQINQDETTPQPVSPDLLNMMDHDGWTLAHILASTGQKEMLVALHQYGSVHLAVPDRRGRTPCDVASDSCKEFLSSITEGKTVRVIVDVSQSSVPSNDLSPHLLGQKDEASQLVIGQLSVLSGMTWSAFDLAIGSVLANSCKMPESDNELPSPNSDKSPSSESSPENIDIGLGVNSIHSYVAGNLHWSVGETPSMQPHEIFNLTSDIVIKLHGNQNGRLDQLAFETFLPLQMIQNYVRIIKQYKSVLLYGSSGSGKSRLAVKLAQYIQAKNKNDRVESDMTYASLNSTFTHKDLCKLLLSKGFLVQSTAGKPNPSHNKSVHILVLDGLDKVGVAGLFADLLPLIENRSNQMTVRLQALSNSAMFSLHENSIIIGTVDGVGPGTDLTVQQHFRWIRVDWEQEPYRSILPRYLFRRLIHEKDGWIPSSPSDETLRVLTWMSGIWKRLNEALTRLSMPEFSTGPKQFFACPINGDAIGSVLRWLCLLWNYSLAPHIEDTFHHNGPRASSTHIQQQNMAASTALYVLLHKAFLPGCPLSDEEADDYFSGFRGISAPAVDVVVEKSSSGGKKPRRSKSLDRSKTSNKAAALLARNQAHMDLISSDSQRNGRSMIPRRVSPKPLKTVTKQNSLPIGSPSKPQETGSVITHQRSQSIPTSPADEPNLLESLLSNHANPSLSEIEQLIELQKTLFGNGGGGGEGGGDRGKNKGLKSSQQTTAGEGQGGVVGGQRLLRRASDGGPVSTGLARTRTKDEGGVWSVWEETV
The following text describes a protein:
Function:
Probable regulatory subunit of the N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation at the 5'-[AG]GAC-3' consensus sites of some mRNAs. Associates with MTA, MTB, VIR and HAKAI to form the m6A writer complex which is essential for adenosine methylation at specific mRNA sequences. N6-methyladenosine (m6A) plays a role in mRNA stability, processing, translation efficiency and editing. Essential protein required during endosperm development and embryogenesis. Involved in endoreduplication, especially in trichomes. May play a role in splicing events.
Subcellular Localization:
Nucleus speckle. Nucleus, nucleoplasm. Note=Nuclear with a speckled distribution pattern.
Sequence:
MEFSSQDDDFGGDDSAANATRASGNRRSFGDLEDDEDDIFGSTTVAPGVRTGMILSLRGSLKNCKDDLASCQNELESAKTEIQKWKSAFQNESFVPAGKSPEPRFLIDYIQNLKSSEKSLKEQLEIAKRKEASCIVQYAKREQEMAELKSAVRDLKSQLKPASMQARRLLLDPAIHEEFSRLKNLVEEKDKKIKELQDNIAAVTFTPQSKNGKMLMAKCRTLQEENEEIGHQAAEGKIHELAIKLAMQKSQNAELRSQFEGLYKHMEELTNDVERSNETVIILQEKLEEKEKEIERVKKGLEIVSELVGDKKDEVDEIDEDAKEEIAGGE
The following text describes a protein:
Function:
Ribonuclease P generates mature tRNA molecules by cleaving their 5'-ends.
Miscellaneous:
MISCELLANEOUS: Present with 1160 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MAFKSFIYSKGYHRSAAQKKTATSFFDSSYQYLRQNQGLVNSDPVLHASHLHPHPVVVANVNYNNVDDILHPHDLDSSINNTNNPLTHEELLYNQNVSLRSLKQQQSTNYVNNNNNNQHRYYSTGPTLPTNQYDPLNFSNRNFQDLSLKTSQPSVQQPQNEYSLLKDENAPVWKEDTEPCLNKSTYLQTHIDEINRCYEQKNYNKINSLYQSLKRNDIVPPLEIFTKVLDSLCKRPLDNNDLDNKMYELLTCYQDMINNRLKPPDEIYNIVLLSLFKGSILAYQFENPNGSDFYKIAIELFNTTTNDPKQKSVVKFRNFSKDVLDYNLLAMNIYPGHITLSKAQQVIKSSPAFIKDSFYFIACFSYAKLTNDKFAIKELYEDFRLSLSSGSPDQGLFDDQFEIYSVILSSFIETGEVELATNLLDDLVSKIQSSNGLASNISLLLSSFLISMSKVDPSKAYEIWFKFHNLNWIPEFSYEFYLVFMANSFQDWNLTKKIYDYIFPMERNLSPLKKQKLSDYLLHPIGVDSITTSLLDYSLQLKDNEVIMKILEESIVKNFSFDIGIYPFVFNYLREIQCGEDYLMRFIESHAEFIKKSNSINKFQFLNMIVDNFQSQSLLNKISHAKFFKNFVEDFNLENCELVSYNGLISCINNFIKIPKTIKDFPYILEIHAILVTKLFDFDTYPILQNGNNEVLLKFRDQIEHQFKMLAQNFCRLNLDPNLLAGVVSQAMKMVNLDDTANGQDLLNFFNHPGDWDKSYPLSLGSFIRNSPRGGIREFTKLSKEGYCFDYDTYKELIIKRAINKQIIDKCLEVCPDSIELKNIVNLMISKIPGRNLTQLIINNPKFSKVFVPNLRNDSMLKLIENCESLSNFIRICDFPEKFKSIAIQAENKNAIELIYERLFDGGKYADILRYNNIVPVLNLELLLKSCIRSGEFKKYESLSKKFNDKISESSKIDIQLEYLINKNDLKGAFTLFEKTPRELRTPHKTMDLYTFALFLDSFNRNITYYESPENTLQFANILSSQTSFINLLSTYNLIAHSDHLMNFNVGGMAAKVKKEILNQMLNNLYDSIRLLSPSIENDKSMKEKLREKVKNYCRFKAYLKSPELDMDELKTLVSVESFLNPFTPSMLFNNLIETIYINEHASSLVLQNGLIYSLQQKGLNKILSYLEESFITSGNDANIEKVREFRSLLRKSKPLQA
The following text describes a protein:
Function:
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
Subcellular Localization:
Nucleus.
Sequence:
MPEGPSVLQWGEVARQFTGREINRVEGNTKTVNKEELVGCRLNDVKVYGKELFLQFVQKSPVRGDERSTWIRYHFLMWGSLRANEYKGISRQSKTGKVPVPRLVLHFAKEEFLAFYGGSMGEVDSPACDQGTDILTASFDVEKATDAIQHAQPVCYTLLDQTCFSGLGNIIKNEVLYAAKVHPLQPGNMLSRQRALCVVEQALAFSSTWMEHKDEHKKFKEHWQIYFKKDCPLGHKTSRDWFGPEDGLQRVTTWCSTCQLLEGASQEQVYPRKIGHVGKRKRSASQKGGKSRRCASTVKKLDVPENSKSSTDRGKRSKVSQTGKQLTGTQKRKKLEKKPVIDPESEEDFCTGKKVKFQPRKQHHRGKSGDQKCSKRRTRP
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSMLARQTVRTARTALRQQQAPLLRRNLHVENTHETSLPFPSGPTRKVPVAISLTTFFVVGFSLPFVAAKFQIAKASW
The following text describes a protein:
Function:
Necessary for use of certain peptides as sole nitrogen source. May also cleave intracellularly generated peptides to recycle amino acids for protein synthesis.
Miscellaneous:
MISCELLANEOUS: Present with 721 molecules/cell in log phase SD medium.
Subcellular Localization:
Vacuole membrane; Single-pass membrane protein. Note=Lysosome-like vacuoles.
Domain:
The transmembrane domain contains polar residues that mediate the recognition by TUL1.
Sequence:
MIALPVEKAPRKSLWQRHRAFISGIVALIIIGTFFLTSGLHPAPPHEAKRPHHGKGPMHSPKCEKIEPLSPSFKHSVDTILHDPAFRNSSIEKLSNAVRIPTVVQDKNPNPADDPDFYKHFYELHDYFEKTFPNIHKHLKLEKVNELGLLYTWEGSDPDLKPLLLMAHQDVVPVNNETLSSWKFPPFSGHYDPETDFVWGRGSNDCKNLLIAEFEAIEQLLIDGFKPNRTIVMSLGFDEEASGTLGAASLASFLHERYGDDGIYSIIDEGEGIMEVDKDVFVATPINAEKGYVDFEVSILGHGGHSSVPPDHTTIGIASELITEFEANPFDYEFEFDNPIYGLLTCAAEHSKSLSKDVKKTILGAPFCPRRKDKLVEYISNQSHLRSLIRTTQAVDIINGGVKANALPETTRFLINHRINLHSSVAEVFERNIEYAKKIAEKYGYGLSKNGDDYIIPETELGHIDITLLRELEPAPLSPSSGPVWDILAGTIQDVFENGVLQNNEEFYVTTGLFSGNTDTKYYWNLSKNIYRFVGSIIDIDLLKTLHSVNEHVDVPGHLSAIAFVYEYIVNVNEYA
The following text describes a protein:
Function:
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
Subcellular Localization:
Cytoplasm.
Sequence:
MSGLPRSVPDVLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAVRAVIR
The following text describes a protein:
Function:
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
Subcellular Localization:
Mitochondrion.
Sequence:
MASLRSACPSPEDDTSSLSSFMTSSTPPSTDSSLDVSYEHLFRSLAQHSRLFPLRSSDVKLLATPTDFYQQLLHNIQNAETRVSISSLYLGTGQLEQALVRALVQRLREKPQLQVQLVLDYSRGQRGGITASSVTMLAPLLKEFPTNVELFLFRVPQLSGLKAKLPPPFNETLGVSHAKVYLVDETLVLSGANLSADYFTNRQDRYVQLTDCGALAQFYHQFVELVTGFSYKVKLESLNGERNDYELLSPVLAHDSEEAKAAMRRDLENLVNPGKHKEDKADELMDAWAFPTLQFTPILMDHDERVLSNFVKNLPRGSQLQIASGYLNFPPFLSELLESCGAGLDVVSAAPRANGFYDARGVKGALPMAYSLIEQDFFERTLDREFPTVLREFNRPGWTFHGKGMWWRPPSPPLANGHKAALGLPQLTVVGSSNFGQRSYGCDLESNLVVFTRNPELRRRLQDEYDALARDTEVVTEQLWRRPERMLHGFFSWKDGHWIRPVSKFIAAYL
The following text describes a protein:
Function:
May be a regulator of keratinocyte proliferation or differentiation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MFPPSGSTGLIPPSHFQARPLSTLPRMAPTWLSDIPLVQPPGHQDVSERRLDTQRPQVTMWERDVSSDRQEPGRRGRSWGLEGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEALARAEKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQEDLEAQVTLVENLRKYVGEQVPSEVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVRVQSLTHILALQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQLKGQVASLQEKVTSQSQEQAILQRSLQDKAAEVEVERMGAKGLQLELSRAQEARRRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVHTIRGLIARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQLSKVAQQLEQELQQTQESLASLGLQLEVARQGQQESTEEAASLRQELTQQQELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKNLMLATLQQEGLLSRYKQQRLLTVLPSLLDKKKSVVSSPRPPECSASAPVAAAVPTRESIKGSLSVLLDDLQDLSEAISKEEAVCQGDNLDRCSSSNPQMSS
The following text describes a protein:
Function:
GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine.
Subcellular Localization:
Cytoplasm. Golgi apparatus.
Sequence:
MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPGWSLQEKYNSRAAALFRDKVAALAEGREWSLESSPAQNWTPPQPRTLPFTAHRASGQLQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGPDHFQNSTIDQSFWETFGSAEPTKARKSPSSDSWTCADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGAKKAVPLAVPADDGWDNQNW
The following text describes a protein:
Function:
Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses.
Sequence:
MMRARPKGTFADAMRESSPPPPPPPAPASAAVKEDEWEVRPGGMLVQKRSPDADAPAGAPVPTIRVKVKFNGVYHEIYINSQASFGELKKMLSARTGLHPEDQKLVYKDKERDSKAFLDMAGVKDRSKMVLLEDPAAQAKRLLEQRRTDKAERAAKSISRIGLDVDKLATKVSALEAIVSKGGKVVDADVVALTEALMNELVKLDSIAADGEVKVQRRMQVSAYAVALNSLPLLGDEFARAESSTARPAQPNRCDDCAGEAGAEVRGDAGRYPRQERGGAQGQGQGQRRHEWARQGPRAATPAAPAARVAEAELPAALPGASAAHAGLGVVRPAVVGAVHVLGHRDHHHGGRDHHHLAGRRLPDPAVRLGALLKPSLLAARRRAGWSIRRYLPPLSMDLPCSHQ
The following text describes a protein:
Function:
Conducts the efflux of homoserine and homoserine lactone.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIAGLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSLASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDIIVMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA
The following text describes a protein:
Function:
Seed storage protein.
Sequence:
MKLFIILATATLLIAATQATYPRDEGFDLGETQMSSKCMRQVKMNEPHLKKCNRYIAMDILDDKYAEALSRVEGEGCKSEESCMRGCCVAMKEMDDECVCEWMKMMVENQKGRIGERLIKEGVRDLKELPSKCGLSELECGSRGNRYFV
The following text describes a protein:
Function:
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity). Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity). May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton. Note=Associates to cortical microtubules (MTs).
Sequence:
MGKTPGKWIKTLLLGKKSPKSNSDNRSQKLKSAKKEELVESVTEDLSNLTVDPPVVSSQPVPASTAQNVVSPINGDESKDNLESRNDLGEVELEQAAIKVQATFRAHQARRAFRTLKGIIRLQAVIRGHLVRRQAIATYSCIWGIVKFQALVRGQKARSSDIAIQFQKKHMEASDSEVLQSSTCSWMDNPTKFVFVDKLLASSPTALPLKIQYGPEEPNSAKVWLERWTQLQVWSSGSRVPRIEIPKSQSKKRNYQAVVEAEKKRPKRSIKKPSGTTSGTGPSRFTAERNKPKRNVRKASTLSKDPLRNESDKANHNSRKSRSGSKEGSPLEIKDEKPSPSLKRSSLSNGSKKATLRSAEKKKKDIPDSSVQIQPEGKVSENVLEGGDNIEFAEKEKDTTDSVQIESEGKVSGNVLEGGEGENIVFTEKEKDTADPVQIEPERKVLEEGDNIESSGKEKDTGDSVQIESEGKVLEGGDNIEFGEKEKDKADAVPIEFDIVKDEKSPVLDRTEEDELKTAETSDKAEALKCADVKVSSENGNVGSDNTKQSEKRALLPANIDKQDDGLTLSGRKIPSYMAPTASAKARVKGEASPRFAQAKTEINGALRRHSLPSPANGKLSTTTMSPRAQKLLLASAKGSMNGDKSFTSSKDITHKSTRTDWKR
The following text describes a protein:
Function:
An ATP, Mg(2+)-dependent DNA 3'-5' and 5'-3' helicase that may be involved in repair of stalled replication forks. Stimulated by both ss and dsDNA. Unwinds both leading and lagging strands in replication fork structures, unlike orthologs in P.furiosus and M.thermautotrophicus which only unwind the lagging strand and only have 3'-5' helicase activity. Preferentially binds dsDNA with overhangs or branched DNA. Able to anneal DNA substrates that could form a replication fork-like structure, has replication fork reversal activity (at least in vitro).
Domain:
DNA-binding occurs via the first 2 N-terminal domains, which are also responsible for ATPase; The central region (432-645) which is structurally composed of 2 domains (432-500 and 501-645) is necessary for helicase activity; The C-terminal region (646-704) inhibits ATPase and helicase activity.
Sequence:
METISIDDLPLDIKIIDILKRRGIRTLNPPQSEAIRKGLLDGKRLLVTSPTASGKTLIAELGMINYLLSKGGKAIYITPLRALTNEKYNTFKDWETLGIKTGMTSGDYDTDDAWLENYDIIVTTYEKLDSLWRHKAKWLNEVSYFVLDEFHYLNDPERGPTVESVAIRAKKRGIVLGLSATISNGKEIANWLNAELVATNWRPVPLKEGIIYPEKKGFVVVYKDNTSRKVYGDDAIIAYTLDIVSKGGQVLVFRSSRKLAENTARKIVQYMNFVKLEDKKLLEIARKIKEVEDAGSNEKEDLYNLVLRGVAYHHAGLSKGLRDIIESSFRDRILKVIVATPTLAAGVNLPARAVVIGDIYRYNRKVVGYMDLIPVMDYKQMSGRAGRPGFDENGEAVVVVRNKREAEKVYERYLMSDVEPIESKLGSESAFYSFLISIIASEGEKTTEELMEYVKETLLPKELAKKYFRSGLDWLLQHDIFAEISDKITLTRFGRRISDLYINPFTAVTIREALEKNEKGCEIAYLHLLAYTPDGPSIGVSRAEEDALIDELNCELFVDEPEDEYEFSNYISALKVAYIVYDWVNEIDEDTILGKYGIGSGDLRAIIDTMDWLTYSGYHVASVLELKDHKDILEELHARVKDGVKPELIELVKIPGIGRVRARLLYQHDIKKPEDIVLNPEKVKQLLGPNLGEKIVREAARTIA
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDFNKIGDENVVFQIFKLEMLIMSEFPSFIEEKDKLLCLNVLANLLGGIFENEDKIIPNYKEAVIAALFERLLLSSNQKSTSKSNQMIKLLNNSLAHNNGLPSQRCNHDSKLVYMSLVQNNGLPGQRSNYVCCPLCMEQHCIELLTYQLFAKWRNFPRIDFSPVLQGNRGPRFFYTCFLCNSTFLASA
The following text describes a protein:
Function:
Probable transcriptional repressor required for the deposition of dimethylated 'Lys-9' of histone H3 (H3K9me2) on asynapsed chromosome pairs (both autosomes and sex chromosomes) during meiosis, but this does not seem to solely affect the transcriptional status. Plays a role in ray fusion and patterning in the male tail, and this may be through activity of the histone deacetylase complex (HDAC).
Subcellular Localization:
Nucleus.
Sequence:
MYNPPPGGGGGNNGGDQSQQQPTNNATLFLLQMIQQSQHQQQHQNQQQQQLELQIRDQERILIEQQRMQHQQQQNQLLQGLNQFPFNPLGLFQVQAAVQAAQAQFAQNAQGSPIPFHIGSPLQPSHSPAASALQQQYLLPSHSPAITPFARNSEAARNIEQFIAQEEAANVPRANSQQQSPLIRPIPQQQALNIQNLTSTQQAQQILAHHRQVPVQQVQHQQHIPTPPLALPIAQQGPISNEVPSVPPVVPATSAGCPQREPRQQQGGRRQNRPGRRKKPEGPPRVDEALAYLRVIKSTFSSDVPVYHRFLEIMKDFRAQRIETPDVIEQVAELLYDSPELVLGFNTFLPTGYRITLTPDRKYVFSSPQMQPRVLLSPDERRARAIEAGAQAVGAIELGSQEGISKDEDRTIEDEDMDKSKEKDDVDGIDDEDDEESGIEDKNNEEMMEEDNHLIEEIICDDRKKDDCEDSQQEIEMSSELAAHTLNIIELLKKSFLARPTKLVDFMTFIDFFMSDQQYKKDMEKLRKDDEDDEIEENEKIEVDDVPGPSNAPQEIKKPDDIEKKDSSKNLQIEESCSDYLVSMLANCCIGEPDLLAATIDFLPYLGKLLVNGSDAIALKIKTILHFSATNDRNDIPPVNRVNPSDVDMDLVKQMEKCKMGTKKNEKLKLKVAGQGDEGATVELMILKKSYRILYERLKSRTTPNQLSHLMVLINAYANLDITREQLISELPKIMGTSGSDLEMIILQLLGAEKEPKNRPENDMDAVMRKDLPAIQPKRGLRDQKMLQQVKNVEAATVCTLGPSYRFMKDTKATDCSGRVELDDDLKGVLNDTWTSIPSWSSEDTGSQAIKKSNLEEFHFKTEDERYELDIIVDSNRTVIEQLSKTLRDYEAMSDEDKKSFKLDKWLNASSRSTTIRVLAKVFTNSAQDFIDAAQKNPLVGLRRILESLKEKDLLWSRFQQDTNRTWRDALDKQMSAATTILNNQHKNYDQKAFKSKPLVNQIEQICEERRKNNSTDTSPHLILEYTPERKVYRDVNDVTGHFFHDLSGTKCDRDRTKIVLFSYRILMEWLCQEGQQVQIDLDNGEIFKFQGDLNEDENLMTLLNMDGRRICGDRVVPVSTSLESNESSIDHFSENLHQKRTRRTFYGDDSVYMIIRYHHMIQERFAKILSTQAIYAQEHFDNQKKNKRWEDGIGADMHGRKALQENIKQRRAAVNDIRNVRSCPSSSYETTLRELKQLGNAQMDIVAFEEAVKNLFPGDIVLFNNIDKLFSSLAKNIHHATCAEERENPIKLYLKYRQRIMNAERDEDMESVIQEYGQTAEEVLRGKNTYRFEFVEEQNKPFIKIWVIPREEKDDDDDDDEEGNEGGKDEDNVKDEDDGGDGEGRDGPDDDQPPPSNDDGDDEEDEDDEEDGPSGADEPESTSGSGNVPMDHLNIGENFLWSPPEEKVCTGKMTTNEKEQRNSVDYMKVTTTPRLRIHKRMLKEHKGCNVELMTGFQQLSAIVPLM
The following text describes a protein:
Function:
Aspartic proteinase that can use azocasein as substrate and regulates endogenous sugar levels (e.g. sucrose, glucose and fructose) by modulating starch accumulation and remobilization. Influences general morphology and development.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MYINTLFWKQNPTGDKKNQEEKMQKTLLSCLITTLLLITVADSMKDTSVRLKLAHRDTLLPKPLSRIEDVIGADQKRHSLISRKRNSTVGVKMDLGSGIDYGTAQYFTEIRVGTPAKKFRVVVDTGSELTWVNCRYRARGKDNRRVFRADESKSFKTVGCLTQTCKVDLMNLFSLTTCPTPSTPCSYDYRYADGSAAQGVFAKETITVGLTNGRMARLPGHLIGCSSSFTGQSFQGADGVLGLAFSDFSFTSTATSLYGAKFSYCLVDHLSNKNVSNYLIFGSSRSTKTAFRRTTPLDLTRIPPFYAINVIGISLGYDMLDIPSQVWDATSGGGTILDSGTSLTLLADAAYKQVVTGLARYLVELKRVKPEGVPIEYCFSFTSGFNVSKLPQLTFHLKGGARFEPHRKSYLVDAAPGVKCLGFVSAGTPATNVIGNIMQQNYLWEFDLMASTLSFAPSACT
The following text describes a protein:
Function:
Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure.
Subcellular Localization:
Vacuole.
Sequence:
MVKKLNVHVTISDASVVNKSYVQYTTRVRVQHGSESAVEYKCRRRFSEFLQLKLDLEREFDAEIPYDFPARKFNLWNMKSRSCDPAVVDERRERLTSFLTDLLNDSFDVRWKTSPTLCAFLNMPDDWWQQSEQRVSSAAASEADSVEQLQDVSKWLESIRDAKSQFEDANRNGNNITMMRIRLKLQKLEEALAVIQENKLVGEGEISRRWIILNALKADLNKQSGALRPRSNDNEYMQRELLKEQLLPAKSEPHRPAAGRRKLGETSQTVGLNNQQLLQLHKDSMKDQDFELEQLRSIVQRQKIMSLNMNQELAIQNEMLDMFADDVNATSNKLRMANISAKRFNERK
The following text describes a protein:
Function:
May be involved in cell cycle regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSDKKGDKFNDHGKDRDRSRSPHRRPENVALDAKKRLKTMGIQMKLSSQKQTAKPKLTIAAAFNQESDEEPEEMPPEARMRMRNIGRDTPTSSGPNSFGKTKQGFSESKKPFDQSPDRANNTAK