lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Subcellular Localization:
Mitochondrion.
Sequence:
EDEVDSLKYNLLHHSLKHVIKHGWSKEAISLGASDCQMSPMAHGLLKNGEFILVDHFYKSANEELRDYLQQRNKKLYVDLSLIVYALKFRLQLITPYIHVWPEAMALMSRPFNASRSVRNLAEMLDDVWWYAGDVSTDFSWYTKRATLACIYKSSELSLITDRSPNFEETWMFMERRFLDANLFTKCSKQVGW
The following text describes a protein:
Function:
Part of a translocon most abundantly expressed in etiolated plants and involved in the protochlorophyllide-dependent import of the precursor NADPH:protochlorophyllide oxidoreductase A (pPORA).
Subcellular Localization:
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Sequence:
MEAALAACALPSLRILNTKPRFRCSFSNPSLPISPNSLITRKSSRFTTAVSSPPSSSAATSTNSPPEPEALFEPGSDKFDWYANWYPVMPICDLDKKVPHGKKVMGIDLVVWWDRNEKQWKVMDDTCPHRLAPLSDGRIDQWGRLQCVYHGWCFNGSGDCKLIPQAPPDGPPVHTFKQACVAVYPSTVQHEIIWFWPNSDPKYKNIIETNKPPYIPELEDPSFTKLMGNRDIPYGYDVLVENLMDPAHVPYAHYGLMRFPKPKGKYIICISNSCFNPFTNLQILLAEKIDREGGKPLEINVKKLDNKGFFSKQEWGYSNFIAPCVYRSSTDPLPEQEHEYPAPAASDKAALSKRRLSLIFICIPVSPGRSRLIWTFPRNFGVFIDKIVPRWVFHIGQNTILDSDLHLLHVEERKILERGPENWQKACFIPTKSDANVVTFRRWFNKYSEARVDWRGKFDPFLLPPTPPREQLFDRYWSHVENCSSCKKAHKYLNALEVILQIASVAMIGVMAVLKQTTMSNVARIAVLVAAVLSFAASKWLSHFIYKTFHYHDYNHAVV
The following text describes a protein:
Function:
Transcriptional regulator that plays an essential role in the activation the type III secretion system (T3SS) operons. In addition, ExsA directly regulates the transcription of ImpA virulence factor that cooperatively inhibits the functions of host macrophages together with the T3SS.
Sequence:
MQGAKSLGRKQITSCHWNIPTFEYRVNKEEGVYVLLEGELTVQDIDSTFCLAPGELLFVRRGSYVVSTKGKDSRILWIPLSAQFLQGFVQRFGALLSEVERCDEPVPGIIAFAATPLLAGCVKGLKELLVHEHPPMLACLKIEELLMLFAFSPQGPLLMSVLRQLSNRHVERLQLFMEKHYLNEWKLSDFSREFGMGLTTFKELFGSVYGVSPRAWISERRILYAHQLLLNSDMSIVDIAMEAGFSSQSYFTQSYRRRFGCTPSRSRQGKDECRAKNN
The following text describes a protein:
Function:
Metalloprotease.
Subcellular Localization:
Secreted.
Sequence:
MLPRSVIRCFIGFSFIIIFDFTVILANKLPLNSDDIKPQKYNNRWEFENGAEKIERREEGQPVPTVTIPKEGPFHWKWTWNSKVNTTSTSEATTGTTTTTKATTTTSSPTTSKPRVYALRPAARKSLRNALRGTTPEKRKKQLAQMGKKMKINKISKSQSNKLHKTYRKVKISENPPALDMFEVNEQAGLNAYLFQGDINLDDKQIAEFTASAKSSSRRKRQIQNSALFWPDKIVYYYFDPGLGTNMQQIVTEAMEYLQQNTCVKFVMNDTATNRVKIINGVGCYSNVGMLGGEQTLSLGSGCELVGTAAHELSHTLGVFHTQMRSDRDDYVTIDLTDVSVSSEPNFYKMTAEESTNLVDYEYGSFMHYSGRAFSTGVDSIVPKDPLMVYTMGGRVVSFLDIKMLNEHYTCSCPSSLNCANGGYTNPSNCTVCICPWGFGGTLCDERADTGCGSELTATDTWQQSNYSFGDPTNSQTARPRFMYCTHWIKAPVGKQIQFRIDAAQYHQCQYACPFGGLEPKLKSDVTVTQARYCCNEFFGEVMTAETNPLPVFAFSRYYISVWSWSYRYVDAIPTSCVDLSDAVTCLALKSSYDQGCSLYDTAQLKVMCAVTMDLCGKAVSGSGTCQDRFPKSQCSTYSSNGLCTSQLPLIAEFSCASTCGFCVNPV
The following text describes a protein:
Function:
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSSNPSITIIGSLNYDLVTYTNKVPQGGETYQANSFETHVGGKGLNESIAVAKLTPKNSVLLSSTTTTTTTSGDGDGAIRMVGKIGDDSFGQQLKQFLIDNKVNVDHVHTVNNQTSGVAVILVEEETGENRILITSGANGELKLDDKEYESIFPKTTGSITTTKEGEGGYLSFVILQNEYPDTVKSINWIKSNRPQLNIAYNPSPFKSELITKELLSKIDLLIVNEGEALDVANHLLKNSHQQDLIDKINQINKSNVTNSTGDNHTVLVEVFSKLAIELQKLINPDNIQIIVITMGSKGSIYIAKNSGGGGGGGGSQTTPQFIKSRKVEKVIDTTGAGDTFFGAIVSNLALGKSIDYAIKFATTASSLTIQKKGAAEGIPSYEEVMEIL
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MNLINLSKRFNKISLLNNNNNNLNKISCRLITTSTNTPISINKLNLNKSILNTINTESIHNISYLDSDLNKNYYSTSVSRKFKNLNRDKKKKEKKDFNKFGFSKEILDSIKEKEWEKPTPVQSEVIPLIFKGRNILFSSVTGSGKTAAYALPFIQILSTFKRNKLEYLKNNEFNENYQLFNKEDENDGEFKMKQKESEEEYEEYEDNEEYEEEEVQSEEEYEIEEINESEIEGLEEFKENENKPSTNENDEYFQEEEEEEEEEEFEVEDFDENGNLIKKSEEEINNIERLKRLKNRNQKKPFNEVDPIGIILLPSKELALQVSKEISDLVKNVQFGKEISSIGNLRVLTLIGGVGEKKQIETLKSGVDIIVGTPGRLVQLINQEVVSLQQVRMTVVDEFDKLFNLGFFPDIRDIFDFLPKVRSRSRPFTMQTVLTSATLNHKLDELITRFAPNHLMVDLNKDLSAPTTVKQFFYHVNYRLKSHLLLYFLRRKGKTSLKNRKVLVFARTQQRVEKLTAMLKEYKINALSIHADYSITQRNKILEMFRDEESGYNILISTDVMARGVDIDTLEAVVNLDVPHVSEDYLHRVGRVGRNGREGFSLTFVSPVKQIFKIGERTVGLDESHLIDNIERSTGITSKFTKIPGPWVENRKQLSKLNNSTNQSFSNNKNKPTKNNKYNDDNDYDDDDEDYQDYQDKKPKTQLPLDKETKYHSKQEKRAVAEILLKKNIIETYKGPQTRDGLPRVKFNPNAKIRDKKISKIVIDRKGEIFDLPQLTDFKEGQYHEVVNSFDRKRAIKRGIKLPQNQTHVFLPSKIETKRSTKNIEKNPNRYNKKPDSNLYNVKSDN
The following text describes a protein:
Function:
Required for resumption of chromosome replication after DNA damage, specifically in S phase. Is recruited to chromatin in response to stalled replication forks and acts as a scaffold during DNA repair. Required for the accumulation of the Smc5-Smc6 genome stability complex in foci during replication stress and for activation of the intrinsic SUMO ligase activity of the complex by collapsed replication forks. In pericentromeric heterochromatin, enhances Clr4/Suv39-mediated H3 Lys-9 dimethylation (H3K9me2), required for stabilization of stalled replication forks and accurate chromosome segregation during mitosis; Required for mitotic fidelity, specifically in the G2 phase of the cell cycle. Plays a role in chromatin organization.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to DNA double-strand breaks. Localizes to pericentromeric heterochromatin during S phase.
Domain:
Forms foci at DNA lesions through its gamma-H2A-binding C-terminal BRCT domain.
Sequence:
MLAAESSNKELFIKNDGKALSFPYDWKLATHVICDDFSSPNVQEGSKRSLRLAKTNWIRDCVDKNTLLNYSFYSCNPYLLFKGICASSCQIDSYQSSLIDDALETFGGRFSKGLMKSMTHLFTYSGMGAKCKKVLDKPSLSIKLIHPQWLLDCLQFGQLIDQDPYLFPNPSYKKNDSSISKAEPTSLFRNVLHGKRIYFSNDLNLPTNFRHSLQKFSVGIGAKIAESINDCDIFIGLKRDTIEFNLASNKNTTIGTISWLLNLFVLGSWKSPLLNALHYPFPSVGFLKDQMVAVTNYTDAARIYLEKLLLACGATYTKDLKPTNTLLIAASSYGQKYGAAKVWNIPTVHHSWLYSSFKNLSSQAFTDFPVPLDDSYMDFIFPCPLNVEKGSFEDTLKSSLTKGNSEVLLDDLSDPSVSSIKGNKTNEELEKEFKSTSDNFGKHIILTSSFSNQSADKGSSLAAEDDRNDEGSTITGVNRELQDEGRLEIDAKSSKTNTPPSPLLVGTPSKESLKEASSDDELPVLATKLVDNVIKEKSPLSLTPKVVVPSHKETYTDEKKLIDELDRVNPLNSSQLLRSKRKSAATALSMLQNVIMPDVLAFEREKKRRQTHRSVSSGEVSRESSESRNTNAKASKRVYITFTGYDKKPSIDNLKKLDMSITSNPSKCTHLIAPRILRTSKFLCSIPYGPCVVTMDWINSCLKTHEIVDEEPYLLNDPEKELELGCTLESALKRARAQGPSLLEDYVVYLTSKTVAPENVPAVISIVKSNGGVCSTLNVYNKRLARHLEDGNVVLITCNEDSHIWTNFLDNASQNKTIFLQNYDWLIKTVLRQEIDVNDRIADEFARAV
The following text describes a protein:
Function:
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
Sequence:
MVCAYHSILGGHGLHTSSLHSLPRDASLPPFRSIHHSRSRKETTPPLRRTKPDPPLPSPSHVSHRALAATLARHSSAKTTSAPRNLSVWELIEKRWWTWVKSSTPRSTSTTPTSTCKHKIVAPRCAPFPISSVRCGWQNPNPFFPRWHVVLPPEVAKLLPKNRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRRINYQQQEEAAVAQSWPSEPPVARAATRNV
The following text describes a protein:
Function:
Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2).
Subcellular Localization:
Nucleus.
Sequence:
MNTAPSRPSPTRRDPYSFGDSRDTRRDRSPIRGSPRREPRDGRNGRDTRDRDIRDPRELRDRRDSRDIRDHRDSRSVREARDLRDFRDFRDLRDSRDFRDHRDPVYDRYREIRDSRDPLYRREGSYDRYLRVDDYCRRKDDSYFDRYRDSFDGRGPPGPESQSRAKERLKREERRREELYRRYFEEIQRRFDAERPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLIFLNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKNDCREKEREEIARQAAKMANDAILQERDRGGPEEGGRGGHPPAIQSLINLLADNRYLTAEETDKIINYLRERKERLLRSSADSLPGPISRQPLGAASGSSLKTQPSSQPLQSGQVLPSATPTPAAPPTSQQELQAKILSLFNSGAVAANSSSASPSVATGSSQNQNFSTAANSQPQQRPQASGNQPPNIVGQAGSARNMGPRPGAPSQGLFGQPSSRLAPASNMASQRPVSSTGINFDNPSVQKALDTLIQSGPALSHLVSQTAAQVGRPQAPMGSYQRHY
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSEAIENLSVILLTLRKKLTVVAAVLFTGVVLSFQFTGPLIERMKEDLLPEGAKLVYVSPLEVMMLKLKLSFIIGLLLTLPFIAFYAYRAVSRRFSLRNPIQIGKSQFLLLSVAALVMFVIGASYAYFFMLPLFLDYLYLNAAGSGVTATYSIFKFISFAAAGTALFGLIFELPIVLTFLTRNGFIQYSTLVTYRKHIYIVFLVAGAIITPPDVLSQVMVAVPMVIFFEVSMVVVRVLGVKHKVSQPDHSSASRVSERS
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts on the folding of rhodopsin RH1 and RH2 (but not RH3) and is required for visual transduction.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MKSLLNRIILCSAFLAVASGLSFTVTSRIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDTDDFPVEPVVISNCGEIPTEQFEFYPDDFNILGWIKAAGLPVTSSFCVLLIFHYFFRQLNMYC
The following text describes a protein:
Function:
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
Sequence:
MGEVQREKVAVIIGPTAVGKTKLSIDLAKALNGEIISGDSMQIYRTMDIGTAKVTKAEMDGIPHYMIDIKNPEDSFSVAEFQERVRKHIREITERGKLPIIVGGTGLYIQSVLFDYQFTDDAGDVIYREQREKLALERGVEYVHEKLQEVDPESAERIHANNVRRVIRALEIFHTTGEKMSEQIEKQEKELLYDVSLIGLTMDREMLYDRINLRVDLMMEQGLLEEVEGLYNRGIRDCQSIQAIGYKEIYDYFENRASLEDAVSQLKTNSRRYAKRQLTWFRNKMDVTWFDVTDGEKTSEILRYIEGKLQVKSNNSK
The following text describes a protein:
Function:
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
Sequence:
MALIQTAHDACSRKVHCVRKGYLNDPFVSFFEKDHTIVNSPLMNRGTWLRTTAFENCVRGFATAAGQPIQVINFGAGMDTLYFRLKHSDPQFPVQKFMELDLADLVAEKERIIKRHSEMHSLVGSQYVLVSCDLYDAKGVAKALKEHLHGGTPTIMIAEMVFVYIEGSVTTNLLRTVMSDVIEPGTKTMLVTYDAIQPFDRFGKVMVENLQHFGADFKGIGDFPTPEAHAGRCSELGFKAVKSVTMKNLYLGVPRQIQIRLNKLEMIDDWEEWNLMHEHYCFVVASTEDAPLPKLF
The following text describes a protein:
Function:
Possesses transactivation activity in yeast cells (Ref.1). Involved in the regulation of stomatal aperture. May modulate the expression of genes that control stomata opening during heat shock or drought stress.
Subcellular Localization:
Nucleus.
Sequence:
MGAMDVQLESTAVQHGQAKINVEEHALVSLLSDEKYATEKTEDVDPDDYEKLEEGIMQYGCAHYRRRCRIRAPCCNEIFDCRHCHNETKNSIKIDAVKRHELPRHEVQQVICSLCGTEQEVRQVCISCGVCMGKYFCEVCKLFDDDVSKQQYHCNGCGICRIGGKENFFHCSKCGCCYSIVLKNSHACVEGAMHHDCPICFEYLFESTNDVSVLPCGHTIHVKCLREMEEHCQFACPLCSKSVCDMSKAWERLDEELATISDTCDNKMVRILCNDCGATSEVQFHLIAHKCQKCKSYNTRQI
The following text describes a protein:
Function:
Together with BCL1, positive regulator of cell elongation at least partially through increased gibberellic acid (GA) biosynthesis.
Subcellular Localization:
Nucleus.
Sequence:
MAQCGGGDVSRHRKGHLDTVESLCQGLLDDVMLDDDKCRAMFGYLQEWQDLASMCYGSLGGEPPLAPEASNGSGSSGGGGSFRKRRPDDAKGESNSICKRQRGKQQQQQQPCHPDQMAAAVGKGRPERARPGAKKKAEVASPKDSPATSASTVTAGQKTDYIHVRARRGQATDSHSLAERVRRERISERMRYLQELVPGCNKVTGKAGMLDEIINYVQSLQKQVEFLSMKIAASNPVVNFNIVEDLFGRQLSQAACNPAALPAMALPMAQVEPSCLQMSPLQQMQTSAGSSGYGLEMVVSNQYSPPGGPMSVPAGASVEPCLNVNGAAGWDIGSHGLFSGFDAPFQSVQSDCLLDNLKMEM
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Sequence:
MLLIDCFRRPSHELQARKKQSSKEVVQMRKLYRDPVKVLLLGAGESGKTTIIKQMRILHIQNSYSFDERLEKLSDIYENIHESIYELVRQVILLELEFDSIANQRCAEYILRMGPQAPWNLSAEYVRCVRRLWSDAGVKRCYKRSNEFQLIDSAKYFLDRVEKISMPGYIPTNGDILNCRKTTTGIQEVRFNVRMPGSLGGGTQEFRMFDVGGQRHHRSKWMQAFEGVQAVLFLISCGGFDQTLREDPKQNRLAEGFELFRGVWHNRFLAETGVIVFMNKQDVLEQKLLAGQSIRTYFPDYDDYVAFADKDQLYDELTRTRSFIRSKLVDITNEPPRRTSHLVGRKRTCYFHFTIATDTQNVRTVFNDVHNIILTKNLSKMDLL
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis. Required for sperm flagella assembly. May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC). ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme. Nucleus.
Sequence:
MLSKRTHAQQQQRINRERVSEAMVFDNTQQYKQMEMKNTMMQIDERAVQRRNWREKMMEVDEAEKRDAYFKHQESERLRRERQEEEERMEEEAKRMNEEKIRNEKIRQKIVSNNEELKKLERQIQAAYAMKSMQEQMKKHGVSKQQEVAKDIEYAKILEEQNKKTNEKMMEDERMKLMASESYKKDLQLQKQTSELLKQEMRNKMMDWDKHLVDEEVRKIKEEDETSAQLARERRENYRKAIEEDEMTTAKMKMMMKMKTMMEEERIERYEKEKMLEEERRRNVRVEQNVAKERVKNELAARLKEEQEQRDELEQARLLLSQEELEQRHKINEQEKEIKRLREREELQRVREEMMMMRERMRRRDKEEEELFKKEMMLKFAEGDRLEQMNAQKQRLKRLEHQRQIEMMLEDKRKHQEMLREQELKALENEERIKAIEKLIVEEERKKLLKLHAPNLIGYLPKGVIRDENDLQMLGPDFIDSYQTIYA
The following text describes a protein:
Function:
Required for meiotic recombination.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPPKGLSLAEKRRRLEAIFHDSKDFFQLKEVEKLGSKKQIVLQTVKDVLQSLVDDNIVKTEKIGTSNYYWSFPSDAKRSRESVLGSLQAQLDDLKQKSKTLDENISFEKSKRDNEGTENDANQYTLELLHAKESELKLLKTQLSNLNHCNPETFELKNENTKKYMEAANLWTDQIHTLIAFCRDMGADTNQIREYCSIPEDLDDLQLPIL
The following text describes a protein:
Function:
Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MRMRSPVWRLLTALAVVFGTAVAFAPIPRITWEHREVQLVQFHEPGISNYSALLLSEDKDTLYVGAREAVFALNAHNISRKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSASALYVCGTNAFQPTCDHLNLTSFAFLGKNEDGKGRCPFDPAQSYTSVMVDGELYSGTSYNFLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVMRESPGGGGGGDDRVYFFFTEVSVEYEFVFKLLIPRVARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSNLVFNVLRDVFVLRSPDLKEPVFYGVFTPQLNNVGLSAVCAYNLSTAEAVFSRGKYMQSATVEQSHTKWVRYNGAVPTPRPGACITREARAANFSSSLNLPDKTLQFVKDHPLMDDSVTPIDGRPRLIKSDVNYTQIVVDRTWALDGTVHDVMFVSTDRGALHKAISLDNSVHIIEETQLFQDFEPVQTLLLSSKEGRKFVYAGSNSGVVQAPLAFCGKHGTCQDCVLARDPYCAWSPATAACITLHQTDRPSRGLIQEMNGDASACPDKIKESYRQHFFKHGSTAELKCSQKSNLARVVWKFQNGVLKAESPKYSLVGRKNLLIFNLSEGDSGVYLCLSEERVKNKTVLQVVAKHVLEVRTVPRTLAASTSPATQTEGRKITSRVSVGFTQSSPPQTPAVRVTTPGAIAPPSSPEAPTSTSCEPKIVINTVPQVHSEKTMYLKSGDNRLLMFLFLFFFVVFLCLFSYNCYKGYLPGQCLKFRSAVLLGKKKPTADFSDCEQSVKETLVEQGSFSQQNGGQPKPALDTGYETEQDTMASRLPTDREDSQRIDELPVRDRPFDVKCELKFADSDADADGD
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Miscellaneous:
MISCELLANEOUS: Present with 6500 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Sequence:
MENSMMFISRSLRRPVTALNCNLQSVRTVIYLHKGPRINGLRRDPESYLRNPSGVLFTEVNAKECQDKVRSILQLPKYGINLSNELILQCLTHKSFAHGSKPYNEKLNLLGAQFLKLQTCIHSLKNGSPAESCENGQLSLQFSNLGTKFAKELTSKNTACTFVKLHNLDPFIFWKMRDPIKDGHINGETTIFASVLNAFIGAILSTNGSEKAAKFIQGSLLDKEDLHSLVNIANENVASAKAKISDKENKAFL
The following text describes a protein:
Function:
Key transcriptional regulator of carbohydrate metabolism. Binds the promoter sequences of the glycolytic genes at the CANNTG motif and activates their expression during growth on either fermentable or non-fermentable carbon sources as well as under hypoxic growth conditions. Complete glycolytic activation by GAL4 and TYE7 is required for full virulence. Involved in biofilm formation and negatively regulates hyphal formation under hypoxia. Also controls the expression of the copper transport protein CTR1.
Subcellular Localization:
Nucleus.
Sequence:
MSSFQQENQLNANNNNNNVMNEYISYSVPLSPVTTNENPQDYWMNGLIANSVPISQTTSNSDINYSQPPNPINFNSIFEGVNIFSNDDFTSSSNDISLANSPETNATSDSIAQNLDEVKVKLENHNQARLDALEFAFETKSILKEQPKIKQEPGTKAATKPKRRAPRKKLTESQKKAHNKIEKRYRININAKIAGIQKIIPWVAFEKTAFETGEENETEAEAKNNTRLNKSMILEKATEYILHLQKKEEEYMAENQKLREQVIKLGGEI
The following text describes a protein:
Function:
Endogenous opiate; Stimulates the adrenal glands to release cortisol.
Subcellular Localization:
Secreted.
Sequence:
MFCPSWLLAAAVLCFHSPHVDGGRCSGLIDCMDLESNEHKLQCLRKCRSDQESSRNIRVSSSEHQSSEEQVEEQSLSLGLLLSALSPDSIELQNPTAEAPHGDERRSYSMEHFRWGKPMGRKRRPVKVLSNGALEEEPEESEESVRVERGQSGTLEVQHRNNVKNNGKYRMTHFRWNAPPDKRYGGLMRPYLDESHKPLITLIRNAIGNGQQFTD
The following text describes a protein:
Function:
As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway.
Subcellular Localization:
Lysosome membrane.
Sequence:
MSQSSTRKRLIQWSPHNKSSFIVGSNDLRLYNFKFKDKNEKKNENNINNSNQYNQNNQQQQQQQIQQQQQQQQQQQQQQQQQQQQQQQQQQQQHDIYSPKSITSKYMETYNFDIEYPPDDWVPQEKKTISLMSVNSDVQLMKCMAWCPDESDTNLIACGLTSGRAILTSFSSVNRILKELVPKHTRSCNAISWNPIYTNQLAVGLDKVRGDSSTLIWDINYLQSTTLNNHLHKNNNNYISKLQQQQNNIDQPYIISQISDNSFSTSTDYTDTIYQPISEFTQSEATLALAWLPNNPSCLLVGTGSKWLKLYDIRDVNSSQSVMAHQKSVNGVCVDPFDFNRIATMSEDSHIKVWDLRNLDDPLIIVNSNCKSIQQIDWCPTRSGVLASVGKDKSSIKLWDIKAPIEFSKSPKLESTTLSTGGGGSGSNTSNNLNKRSTSNNNNSQDPINTISKPTKIHHSSDVVSSFSWHPTNECRMLTVSYSGVIDVVSLNENIPISWSPHGGICFSFGNNVLEGPTKGETLEPNILNYKNLINDGRYEKDISSKIKERAIFGYSANVEENINLANKINDENINFLWKWIQKVPIQIQNFKRESSLISTPSISTTTPGGPITPSATTKTIINNNNNNNNNKNINNNINNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNEYNGIYNILIEKDISTVESSNGFVIYKSPNRNLCLSICGWGFNQSLPLENILSRLEKSGEYERAAAIAVFHLDIKRAILVVTNATYNIHPVTQTNHHGHLMRQDREFSLKLLSIALAGFDGSSTSNNNNNNNNNNNNIWKETCKSTAKSFINPYLKTCLEFLASNSDSKDIYSIIEDSRINLDDKIAFSCKYLDYQDLIHFVERNTIRVIECGNLKGVLLTGLTGRGVDLLSNYIDRTCDIQTAVLAISLVVPKFFRDKRVSKWSSIYSDLLDQWELWHERAILDIQTRISGIDQPPTPQIFAKCGFCQNSFAFESISASSIVGRNASSKPNFKAKVPFCPHCKQSLPRCCLCLLPLNCMVPTPEFKKSNTTIGSGGGSIASSGGINNSGSINNPNDSQLWSNGSEPFEDWFTWCQTCRHGGHSQHILDWFKDHSICPVTSCDCRCSQL
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MASIHPQSSSMAGPGRLAAVPEESTNGSASPPLGLYGDWIRTVAVSGTQRRSTILGQSGSSYSSASTSYLSNNSSYSSGLASAAGRLEYFGGQQELKRIARGMVGDGYTQRMVQAFHDASSAPAFKHGGGPAPGHALENWFLELDVGWVLQIHDKHGLRRLLQDKPECTPQDLIERWIRALTVMVASITELVVVAFHGTTAVARFGKASITEMLAFVDNIIPVLEAEKLQVVLDMFICVNEIGATLEREGNKLWEIILNTMKDVRTLAEEDDSWAIEIPRGGGEVHRNTRFIMDCVVSMMNARTSMKHSAPTDNTENLGGLIDGTIDYLKGLLFTKSESCSDQSLRYLFLLNNSYFDLAQELSDVPLPERPSPTRPPQPQARRWTCPATVVQRKGTSAHTASLSAPAPPLHPLDLTQTPKEPPIGRHFYPRPLMGNPGLLPPARSP
The following text describes a protein:
Function:
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MNPLLQDYARILLEWNQTHNLSGAKNLSELEPQITDALKPLEFIKDFKSCLDIGSGAGLPAIPLALEKPEVKFILLEPRIKRAAFLNYLKSVLPLKNIEIIKKRLEDYQNLLQVDLITSRAVASSSFLIEKSQRFLKDKGYFLFYKGEQLKDEIACKDTECFMHQKRVYFYKSKESLC
The following text describes a protein:
Function:
Male-specific peptide with moderate activity against Gram-positive bacteria.
Subcellular Localization:
Secreted.
Sequence:
MKYFSVLVVLTLILAISVGQSNAIFVDVLDNVETALHNAAKAGFKLIKPIEKLIMPK
The following text describes a protein:
Function:
Necessary for the maintenance of persistent fluctuating activities and suppression of acute evoked activities in abdominal leucokinin-producing (ABLK) neurons to negatively regulate neuron excitability involved in nociceptive (perception of pain) behavioral responses.
Miscellaneous:
MISCELLANEOUS: Larvae display an instinctive escape response to nociception (the sensing of noxious stimuli such as harsh mechanical attacks) consisting of an abrupt bending of the body followed by a corkscrew-like roll reminiscent of an athletics high-jump technique referred to as the belly roll.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Membrane; Lipid-anchor, GPI-anchor. Perikaryon. Cell projection, neuron projection.
Sequence:
MVSALKCSLAVAVMISLACSAYAIKCYQCESLTMPKCGLKFEADETLLLDCSRIGPPRYLQNFFPLRNATGCMKKTLESVAGHPQIVRSCYFGDINNIQAGCQSDPSMPFVKQLGCDVCTKDECNGSSSLAPIAGAILLFFGVARLLA
The following text describes a protein:
Function:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
Sequence:
MAILIKNKVPTTLYQVYDNEGKLIDPNHKITLTDEQLKHAYYLMNLSRMMDKKMLVWQRAGKMLNFAPNLGEEALQVGMGLGLNENDWVCPTFRSGALMLYRGVKPEQLLLYWNGNEKGSQIDAKYKTLPINITIGAQYSHAAGLGYMLHYKKQPNVAVTMIGDGGTAEGEFYEAMNIASIHKWNTVFCINNNQFAISTRTKLESAVSDLSVKAIACGIPRVRVDGNDLIASYEAMQDAANYARGGNGPVLIEFFSYRQGPHTTSDDPSIYRTKQEEEEGMKSDPVKRLRNFLFDRSILNQAQEEEMFSKIEQEIQAAYEKMVLDTPVSVDEVFDYNYQELTPELVEQKQIAKKYFKD
The following text describes a protein:
Function:
Component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC). Enhances homeobox protein Nkx-2.1-activated SFTPB and SFTPC promoter activities.
Subcellular Localization:
Nucleus.
Sequence:
MAPVRRSAKWRPGGIEARGEGVSTVGYRNKNVRQKTWRPNHPQAFVGSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEKC
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MEEEEEVSSPVQCCPRDFLRRFGSGGGEELTEAKRGEPSEVEHSLGLSLGGCSGNEPNDRCTASVFPLRKALPEAEAAAAVPADAEEQRKRKRKELQSQKRTRSEKRDRKGDILDEEMEDGPRPSAAANGVVPPALATKPRAGMVDGSKCFRPETQASIGSQGSGCSGVSEFNCGAKQGIEESKPTKAVNATAMNAGRVMGDTKEVERDMMPCVSATGDGPNGTRIEGFLYKYRKGEDVRIVCVCHGRFFTPAEFVKHAGGGDVAHPLRHIVVNPFPSAFL
The following text describes a protein:
Function:
Catalyzes the cyclization of farnesyl diphosphate to multiple sesquiterpenes, such as olefins and sesquiterpene alcohols.
Domain:
The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
Sequence:
MATEGLLSAETDQDVARFLANFPPTEWGYSFASLLPQDSEFESHTKELDLVKEKVKDMLMQSRKELTENIEFVNCLCRLGVSYHFESEIIEQLSHIFISLPKILEENDYSLYILTLLFRVLRQHGYKMPCDVFNKFKDSNGEFKKCMTADVRGLLSLYEATFLSVHGEDILDEALAFTRQHLETLAEKSSPHLARHIRNALHLPFHHAPERLEILQYICFYEGEKSMNETLLKFAKLDFNRLQLLYRKELGLLSRWWKDINLTEKLPYTRDRIVEAYAWAAGIIIDPQFSRARLQFAKHLILISVMDDTYDSYGTFDELKHFTAALQRFTFEPTIELPEYMKFLYNILWNFFQETEKDETQGCACKTSFAREMLKELARSYFAEAEWYNDGVLPTFDEFMQFGLVSSTFDYHASAFFLGVEDLGMKEFIWLRDNPTIAKTAKLFGRLFNDIAIREDEQKKGDYPSAIKCYMNDHDVSLEKAKEDILKMLEDGWKDMNEELMKPTTVPKILTKFSINFVRMSDFTYRGGIDKYTCGTELKEFVKKLTIFPLQI