lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of an antiviral system composed of AbpA and AbpB; when both are expressed from a plasmid they confer resistance to phages T2, T4, T7 and lambda but not RB32 or RB69. Resistance is temperature dependent, it can be seen at 30 degrees Celsius but not at 37 or 42 degrees Celsius. The system impairs phage but not bacterial DNA synthesis (shown for T4, T7 and lambda). Partially suppressed by mutations in T4 gene 41, a replicative helicase; Deletion or mutations in this gene were selected in directed evolution experiments for resistance to intense ionizing radiation (3000 Gy).
Miscellaneous:
MISCELLANEOUS: Part of prophage CP4-57.
Sequence:
MTEIYEQAKHSLQGEDFSSFNYLFAVNKLLSNPVSYDLGRDLIVRALDSRERFSEHTTILKNMVRKSGLFPYLKKEFTSLTPDDLRVLELYRTPFSDGYVFHSMQFHIFDLLKSGQNVVLSAPTSMGKSAIVDSLLGMGTLKRLVLVVPTVALADETRRRLQERFGDRYQIIHHSSQVCHSDQAVYVLTQERVNERDDIVDIDLFVIDEFYKLAFRQLKSGDIDHQDERVIELNIALSKLLKVSRQFYLTGPFVNSIRGLEKLGYPHTFVSTDFNTVALDVKTFGIKANDDKAKLKALGEIAHACVDATIIYCKSPTVAGLVARELIRLGHGTPTENPHVDWVSEEFDADWDYTVALRNGIGLHFGALPRALQQYTADQFNAGKLRFLLCTSTIIEGVNTIAKNVVIYDNRDGTRSIDKFTHGNIKGRAGRMGVHFVGKIFCLEEIPEDNLNQEVDIPLGIQGIDTPINLLASVQPDHLSEFSQDRFDEVFINDRVSIDLVKKHSYFRVEQFEMLQSMFEMMDDNEFSSLVFHWTPATNFLKTFAKIIARLVPHTFSRNGVPVKPTDVMIAKLAGYLSAESYSEYLKNQIDYARQWISEGEKRTLSIALNNDLKLITNTFGYTLPKVLSLMEDVVKHHAVKRGIRSKVDYTHVKLAFESFHLPPGVNALEEIGIPIQTLHRLVDLLEFSDEADVDELSQYLRDTQDIWSRSIGYVDQMFIRRALGIRRH
The following text describes a protein:
Function:
Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MINKAGKQLTWLFALKILSRIFDLSLNILVLRDLEPGIYGLTTNLDLLTNITLFYLKIVLKQTYSRLKDPNQEQTQSAVNLMYFGLLITICIAPITVLVMSYNQSVAFAKTAFLYGISAVIDGASEPYAVQWIIQLKLNVVAKAEGLAVFMKTIVLYILLGKYTRELFQIETVIGFGIAQVIYSIFIFGYIFSLSNQSKFKQLNKEGVYVVAEMKQVGYQFTLMAFMKFLLQELEKIVMVIYNNPIISGEFTLVSHIGSIIPRFIYVNIEQIAFNLFPKINQEEQTQLLQKYLKFLNLVGISIVSAGIPCASAFLQIYGSQWTSDSCILAMQLYCIYIWIMGINGITESYVNSTIDTKDMWWYRYLLIAQTIIYSLSLVILVQMGSSGIIISNILSMSVRIFVSFLIINKQGIKIQWNAIMPKFMILYLLGFLFQYLTEGFQLLVLTALYYGILGLINIKTVTEVIKSN
The following text describes a protein:
Function:
One of the three SNF1 protein kinases (with SAK1 and ELM1) which are required for growth on nonfermentable carbon sources and nonpreferred sugars and for response to environmental stress. Activates SNF1 by phosphorylation of its activation-loop 'Thr-210'. Required for the regulation by SNF1 of the transcription of a large set of genes, the modification the activity of metabolic enzymes, and the control of various nutrient-responsive cellular developmental processes. Also phosphorylates GAL83, MIG1 and SIP2.
Domain:
The C-terminus (residues 351 to 560) is required for efficient SNF1 pathway signaling.
Sequence:
MVLLKEPVQPLPRSSLLYNNASNSSSRIKETRKVKLLYNPLTKRQILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFPSYEEMLNGATSGITMEEYTDAKDLLKKLLQKDPDKRIKLADIKVHPFMCHYGKSDAASVLTNLETFHELKVSPPSSCKRVELVSLPVNSSFASLDSVYMENFDHNNLRTGADRNSTYSPSIYDANTLSPSAYHNIGSRESSYSSFSSFTSSTAFASQISIQDAPAIGDQQCLIGESGSSLRVNSCEFPQYTTMSPVGEYPFESTEASLSSTLTPVGNVPQRIKAHLVEGKSNSKDDLRIEADASLVFEASDAQRTRRRMSLYKL
The following text describes a protein:
Function:
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Sequence:
MNKSTRVLLVSLLSVAVLAGCSKKVKETPPPATDTTAGSTAPTGPSTSGLYGPGDLDTDACLRQRVVYFDLDQDSLKPEFQAIMACHAKYLRDRPSSRITLQGNADERGSREYNMGLGERRGNAVSSALQAAGGSASQLTVVSYGEERPVCTETSESCWSQNRRVEIVYTAQ
The following text describes a protein:
Function:
Uniporter that transports zinc(2+) into polarized cells of enterocytes, pancreatic acinar and endoderm cells across the basolateral membrane and participates, notably, in zinc excretion from the intestine by the uptake of zinc from the blood into the intestine. The transport mechanism is temperature- and concentration-dependent and saturable (By similarity). Mediates zinc homeostasis that is essential for venous angiogenesis.
Subcellular Localization:
Basolateral cell membrane; Multi-pass membrane protein. Note=Zinc can regulate the turnover of protein at the membrane.
Sequence:
MGGQTVWMTLSFKLLLYYCMISLLMPAIFILATRAQVDKFRKFNESTQTKSSQELFEEAFEEQGYYLQRLFLQYGDNGTLTYEGLQKLLGSLGLGEVSVLEIRHGEAKHPSQSISHSHSHEDHHPSQGTTNSPPLRESLDAKSALSGSPAELGRSDYFLHPALRNKQEESVSLLSDHPTEKHLHGNCLNVTQLLWNFGLGQASHITPAHFTFLCPALLYQIESGVCLRHTEDHSQASKTSEGFLIALGWASLALLVISLPSLVALGMAPLLQPSVLQVFLCPMAGMAVGTLCGDALLHLMPHAIFSQHTDHQNAVFKGLSVLGGLYLLFIFESLLGLKQHFKNLKRRKHDAECGRELDALQGTSSANQNESSGHGHSHGQAEPGQTGIRSMAWMVVMGDGIHNLTDGLAIGVAFSQSLTGGFSTAIAVFCHELPHELGDLAVLLSAGWPVRRLLVFSGLSALLGFVGVLAGSALGNHWASHSPWILTLTAGVFLYVALADMMPEMLHGACGSVSPLKRFLLQALGLLTGGAIMLCIALFEDHIAVSLGENSLGEN
The following text describes a protein:
Function:
Functions in the bile acid 7alpha-dehydroxylation pathway, which forms secondary bile acids via the 7alpha-dehydroxylation of primary bile acids, and is carried out by intestinal anaerobic bacteria. Catalyzes the initial step in this pathway, i.e. the ATP-dependent thioesterification of primary bile acids with coenzyme A. Is active with C-24 bile acids with free carboxyl groups such as cholate, deoxycholate and chenodeoxycholate. Produces AMP and pyrophosphate in addition to the bile acid-CoA thioester.
Sequence:
MHKKSACEREGKELKRDFFNKFNLGTSNFVTPGKQLEYVSECKPDSTAVICLDKEQNCSVITWHQLHVYSSQLAWYLIENEIGPGSIVLTMFPNSIEHIIAVFAIWKAGACYMPMSYKAAESEIREACDTIHPNAAFAECKIPGLKFCLSADEIYEAMEGRSKEMPSDRLANPNMISLSGGTSGKMKFIRQNLPCGLDDETIRSWSLMSGMGFEQRQLLVGPLFHGAPHSAAFNGLFMGNTLVLTRNLCPGNILNMIKKYKIEFIQMVPTLMNRLAKLEGVGKEDFASLKALCHTGGVCSPWLKQIWIDLLGPEKIYEMYSMTECIGLTCIRGDEWVKHPGSIGRPVGDSKVSIRDENGKEVAPFEIGEIYMTAPASYLVTEYINWEPLEVKEGGFRSVGDIGYVDEQGYLYFSDRRSDMLVSGGENVFATEVETALLRYKDILDAVVVGIPDEDLGRRLHAVIETGKEIPAEELKTFLRKYLTPYKIPKTFEFVRSIRRGDNGKADRKRILEDCIARGG
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSLAKSVYNTVFKRNSVYVGSIFFGAFAFGIGYDLATTAWWDAHNKGKQWKDIRGKYLEDSE
The following text describes a protein:
Function:
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MASPHLLLPSPSQAAAACTALCCACGVPTPPNPANTCARCLRGAPRHSVVVRCPSCSSYLEPPRRWTRAAPDSPELKHLLLRRVRRRLPRLGASLSGAELVFTEPHSKRLKLRIRLRLRLRIRREVRADVAVEKSHVVEFTVHDRLCDSCGGRARRAMDQCGGGWSAVRASHRRTLLHLQQRLAALGAAGSATRVVVPSAGGGLDFFFASRSHAASLVSLISSMAPARTDSKSNCNSHSNTTHAFSVELCPVCRDDLVFLPREASGSLGGLGPLVLCVKVTDVLALLDVSTLRVVHLGMKEYDWYKFEPALTSRQLVEYIVLDVDAGEAMVSGHRAAYAQVARASELGKKDAIFTVRTHLGDLLSPGDRALGYDLRHGVNLDDVVGSNCLPDAVLVNKIHEKGGGGKLQQDGSSSRSDGVGIDEIAMGIGCIDLNPSDEVELDELFEDLRM
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSKDKELPVQDHIIELLERLRRALISVIISSIAVSIFPDPSSHSYRPLIFSIMDRVRRDMTDLNNPILRPLANIFGIKEVNIDLIAYSWIDSIEVILMLSLLFGLVISSPYIAKQIYDFVEPGLEEREKRIIIPFVLGFSILFSSGVIYAYFVVMPLTIFFLSLIYIASGIKLIFSIEQFFSFIITGLVIVGLFFTFPLIIAVLSYLDILRPETLREKFGYIFFIVLVILAIVTPDPTPVSMIALSVPFLILYYLSYLLARKFGQHVT
The following text describes a protein:
Function:
Potential calcium sensor.
Sequence:
MMAPPPLLLSAAPAGAAASSSARPGSSLQQTQRQGPCDGGRQRRLESLRLRRVFDLFDRDGDGVITPTELSGALGRLGLALDHAAVPAPPAPAQTAPAGTGALEAVVAPYVAPGMTGLRFQDFEALHAELAGDHGDGKEEEEMREAFSVFDENGDGYISATELQAVLARMGLPEAGCMARVRDMIAAADRDSDGRVDFDEFKAMMAGGTATDI
The following text describes a protein:
Function:
Adapter protein that plays a central role in localization of transcripts in the oocyte and in young embryos. Maintains RNA targets in a repressed state by promoting their deadenylation and protects deadenylated mRNAs from further degradation. Binds to and recruits eIF-4E to the 3'-UTR of some mRNA targets which prevents interaction between eIF4E1 and eIF4G. This may contribute to translational repression but does not appear to be necessary for it to occur. Can promote translational repression independently of deadenylation and eIF4E1 binding. Required for correct localization of eIF4E1 in the developing oocyte. Required for translational repression of oskar (osk) mRNA. Also required for the translational repression of nanos (nos) mRNA. Promotes the accumulation of the germ plasm components osk, vas and stau at the posterior pole of the oocyte and is required for germ cell development. Represses orb positive autoregulatory activity which prevents premature activation of orb and ensures its accumulation specifically in the developing oocyte. In 0-1 hour embryos, forms a complex with me31B, cup, tral and pAbp which binds to various mRNAs including maternal mRNAs, and down-regulates their expression during the maternal-to-zygotic transition.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Note=Retained in the cytoplasm by interaction with eIF4E1. Located throughout the cytoplasm of all germline cells and is excluded from the nucleus of nurse cells, oocytes and follicular cells. During oogenesis, accumulates in the cytoplasm at the posterior end of the forming oocyte. Component of the germ plasm in developing oocytes. Does not localize in processing bodies (P-bodies).
Domain:
The YXXXXLphi motifs mediate interaction with eIF4E1.
Sequence:
MQMAEAEQENGAGALKIATNAGATDRPAHQQLPLPVEDQQDEVLTPAEKGKFEYPPPPPPPTPVQAPLATKATALNASQEHDDDEANSEKWEDPCAPPPPPPLPTSAFLATGLGYLKLPAFKLKDALEKAITKLEANKRTLKASPESSRSIKNKNVVALEMLPRRSNPETIGDGSMLASTSTAVMLQTKKPAVIVEMERRCKIINLLAKQNQILESISGEAIPMHGPSKHLHEDEGLTLQVLSARASTPYTQPSSMLSCTAVSCDLEHDSPRKQVASKEAVPEQQSSQVQQKRPPSTGIHKPGSLRAPKAVRPTTAPVVSSKPVKSYTRSRLMDIRNGMFNALMHRSKESFVMPRIATCDDIELEGRLRRMNIWRTSDGTRFRTRSTTANLNMNNNNNNECMPAFFKNKNKPNLISDESIIQSQPPQPQTEFQDPAIVNQRRIGSGRLNHSKWGYNDEDYHSYHNGKSQHMEEVNSKNSKNMTVLQFFDNGEISSQPQRRPNTPVMGMSINRSENDTLHSNESSEDLSRANENYVKRVMSGFLVVSKPKSRDVEDRHHRRYRNQNEEPEWFSCGPTSRLDTIELCGFDEDEEKMLKEGNKNHGLGETERETSKQKMDHKYKWTHAEPMGRSKYMPKHDTNNNHNVENMNNVMATEHQQQKEEKRPGSGRSFQFDKFNQSQQNYESSSYVNHQQPPQTQPQQMQQQSNTNTNNSKFMSFFANEGNSSSSSLNEFFKQAINQGHGNNPEQPKSLGHIGQMPSVDQLEAKWRRNSLNNVGETANKQTDNFQKLIGSLSSAKPQSQAVGYDAISNFIMQQQQYQQQQQKQHLIIQQQQQHTAFLASLQLKAILGRADTQLLLLRLTKGEISKHGLLVQLANPRLTDMDREAITAVLQFTNTQQQQQQHKQQLDMLSSTVIASQLQNLHNLAIVQQTLAARQQPQHNPQTQAPHQLSQEDLQAHANVIMRNAVMKRKIEEQTSKLINGGAKHQAQQQYLNRGQQRQARPDANSNALLHALISGGGNNHASGYPMNGQPQKHHSNLRFGDNQNFQSFESNQPHFATQYKQQYQQSQQQHPHQQPQQLNSLHQNNAGAVNSFNKAQMQAQSAISMLPNSGDEFH
The following text describes a protein:
Function:
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Sequence:
MSTINNPLNIKTRSHSSMGGGMIMDENKVPKSSIGMDKKIGGTTGLKSHRGALSDLTNNTHQTTGMATKTVQLSNNNIIMPQPTNTRNNIITRSKSIIDNGASLRNSALISGVLPNANGPVNKVQKRDIQSMEMMNNIPQQPVMIDDVDNDTNMIQEEQMVIDITEVPENIDIYDSHDPQCVGEYVNEIFAYYREKEQIDKIDKDYIKNQYHINERMRAILVDWMMAVHVRFKLLSETFFLSVNIVDRYLAKVMIPVTKLQLVGITAILLACKYEEIYSPQIKDFVHTSDDACTHAEVIDMERQILSTLQFHMSVATPLHFLRRFSKAAGSDSRTHSLSKYLSELSMVEYRMVQFVPSMIAAASIYVARRMTMKSGPYWNVTLEYYTCYKESEILQCAQELKEVRKRADTSNLKATRKKYLSSKLMEVAAIPVVEF
The following text describes a protein:
Function:
Dimethyl sulfoxide (DMSO) reductase catalyzes the reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS) during anaerobic respiration; it can also use trimethylamine N-oxide (TMAO) as terminal electron acceptor. Subunit C is proposed to be a membrane anchoring subunit.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MADDDTTARRPVLSSFGTLGRGWLGVLALLLVIGLGAWAYQLQHGLIETGMRNVFSWGLYIMLFVLFVGLSAGGLILSSAPKFFHSQRYEGFARLGVLVSLGCIIVAGLLILPDIGRPDRIYQFVTSPDFRSPMVWDFGIVMLYGALNVWYLWLLTRRDLAARGSRLSLWVSDSAAGRDRDRTLMFWTAVCALPAAVALHSVTGWIFATQVGRGDWFSPLVAPVFIAKALVSGLGLLLVVSILADRFTAFTADRGELTSLGKLLGIFLAFHVVYLLAAERLPHAWAHHFGFWAITSNFLIGDTVYFWLWTGLGGAVPLLLLATPSLRRRTAVIFTASVLAVFGTLFEGIRLVFTGYQRVNINAAPGIATGGEYAGLTTDAWATAGTYTPTAVEIAVTVGVISIGALIVMAGLRYLPLQRAAPDAAYATDGGDRTQ
The following text describes a protein:
Function:
Participates in iron-sulfur cluster formation (ISC) pathway for iron-sulfur (Fe-S) cluster biogenesis. Can bind and transfer [4Fe-4S] clusters to target apo-proteins.
Subcellular Localization:
Mitochondrion.
Sequence:
MFNNFLNMYMCTLAEKLCKFKKNNFNNIHRNNNFYRDNNFYRDNNFYRDNNFYRDNNFYRDNNLYTNNNLYRDNNFYRDNNFYRDNNFYRDNNLYTNNNLYRDNNLYTNNNLYRDNNFYNITLRKFHFIQTISNNNFNFEIIKKYGDVINKIMFIHTQKKNKQERFMFNNKKYIKRKEYILNDLNEFISIIPHPEINNEITNNSNQKKNKDNKQNVLSTNQQIITNYNLNHKENVTSNLNFNNKEEDEKKLDKLLKKRNIKKRDIVTITEEAKEELKKIISINKKENNNNYNNMNTICSDNHNDMNTICNDKNILKLFFITKGCNGLTHSFNFISKKDIHKEDEIIYDDQNNILLVIDKNCILYVINTTLDYYKDDLTEKFIFKNPNITSICPCGTSFHFSKKK
The following text describes a protein:
Function:
Binds to GT and GC boxes promoters elements. Probable transcriptional activator. Required for normal male reproductive behavior.
Subcellular Localization:
Nucleus.
Domain:
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. In SP4, the motif is inactive.
Sequence:
MSDQKKEEEEEAAAAMATEGGKTSEPENNNKKPKTSGSQDSHPSPLALLAATCSKIGTPGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQPASSSSSSSSSNNGSSSPTKTKSGNPSTPNQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQINPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVTAGGGTGQVGQPTTTTDSGTSNGNQLVSTPTTSTAPASTMPESPSSSTTCTTTASTTLTSSDTLVSSADTGQYASTSASSSERTIEEPQTPAATESEAQSSSQLQSNGIQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQQTSDAEVQPGKRLRRVACSCPNCREGEGRGSSEPGKKKQHVCHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF
The following text describes a protein:
Function:
Required for normal formation of eisosomes, large cytoplasmic protein assemblies that localize to specialized domains on plasma membrane and mark the site of endocytosis.
Miscellaneous:
MISCELLANEOUS: Present with 5570 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasmic granule. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes at the eisosomes.
Sequence:
MSLISAVEDRDIHNIGKTSGGGSRTSSITSSKKSLKHGSKSLRKPKVYQTTGEPLSREALYKAKLKYGVYQSPAQSYSIGVSDAHAASDKAANLAHDNQTTVEAYKRMFIDPNATKAASKMGPKVVRNNSITSATSKTSKESQTKRKSKESPGAAASKAYSMTMETTSLSSQTNSRSYSITSASSVLSGASGSFNSTVNPKPKTLNLEKVLVGAEKKAESRIKERWEPEKTNFQYGVKTDEHGNLNQFSFSNEMMNNIMAKVDAPKAQDLQKVKKVSAEKEAKSMKFALGAANAVKDMHPGEDIDKSIALKAQKRETYLSQLTSQQVLTLARANVDRQLDIIEKSDMHRKLFTNMEYNKAAVAVAQSNHQKKTEFHNKINMGGGLFLSPEDITKIASGLISPVLGEVSERAEAQRAMDEEIAERTEAYNKSSNEWETMERSIISNDAKVLTTTANRHQTEKKTSQEKIKASFDALVARMDTKVAERETLLEDTKSKEIEFKKQMQQELKDEKARLDQDLEEWGKKCEQDITEARKEQEELLKPYHDDLANAEAEHKTLVEERDEINAEISRLQDAIVDHKRKISGYGNDLDAQKNRNIREDDKLLELGQTKESLESHLNDDVIILANKAKEQAELSTKEARLKQLEVDSLINERKSELNATEIELKKEKLNLLEAMKDVASARGDDKIDEEKVKKLIGMTSEEYLTQNKSVEKNVEDLPTQLEKIEEGDELKKEEIVGAETKNSGGDGVPVSTAAKEATETSSAVQTKEPEEKISIGNKSSGKEDANDCKSAEHSKEISVSQKAGNNKSLGVSPDSLEHTFSGFSQGSSIEDDQDAISNQEKK
The following text describes a protein:
Function:
Histone methyltransferase.
Subcellular Localization:
Chromosome, centromere. Nucleus.
Sequence:
MGPEHVFDELTKALKDPADFVDFDLPSALKEWKLGYYIPIKRNIYLTKKRVEDDGIFCSCSLSSESPVTCGKDCQCGMLFSCCSSNCKCENKCANKSFQLRPLFKTKLIKTEKCGFGLIAEDEIKKGEFVIEYVGEVIDDRTCEERLWKMKRQRYTNFYLCEVSSNMVIDATNKGNKSRFINHSCEPNTEMQKWTVDGQTRVGIFALRDIERGEELTYDYKFVQFGADQDCHCGSSNCRKMVGTSKSFNSFVLHNGNSGSSQDQHDIKKRKTTSDNCIGEIIRLWDRRDKMYVPAVVHDYDEYTGMHTLLLDEETTEKFDMREEDWDFLPRPEDPEEDNY
The following text describes a protein:
Function:
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SEC24 specifically recruits cargo proteins like BET1 or SYS1 to the COPII vesicles. The SEC23/24 complex is also involved in internalization of plasma membrane proteins like the maltose transporter.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSHHKKRVYPQAQLQYGQNATPLQQPAQFMPPQDPAAAGMSYGQMGMPPQGAVPSMGQQQFLTPAQEQLHQQIDQATTSMNDMHLHNVPLVDPNAYMQPQVPVQMGTPLQQQQQPMAAPAYGQPSAAMGQNMRPMNQLYPIDLLTELPPPITDLTLPPPPLVIPPERMLVPSELSNASPDYIRSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCRRCRSYMNPFVTFIEQGRRWRCNFCRLANDVPMQMDQSDPNDPKSRYDRNEIKCAVMEYMAPKEYTLRQPPPATYCFLIDVSQSSIKSGLLATTINTLLQNLDSIPNHDERTRISILCVDNAIHYFKIPLDSENNEESADQINMMDIADLEEPFLPRPNSMVVSLKACRQNIETLLTKIPQIFQSNLITNFALGPALKSAYHLIGGVGGKIIVVSGTLPNLGIGKLQRRNESGVVNTSKETAQLLSCQDSFYKNFTIDCSKVQITVDLFLASEDYMDVASLSNLSRFTAGQTHFYPGFSGKNPNDIVKFSTEFAKHISMDFCMETVMRARGSTGLRMSRFYGHFFNRSSDLCAFSTMPRDQSYLFEVNVDESIMADYCYVQVAVLLSLNNSQRRIRIITLAMPTTESLAEVYASADQLAIASFYNSKAVEKALNSSLDDARVLINKSVQDILATYKKEIVVSNTAGGAPLRLCANLRMFPLLMHSLTKHMAFRSGIVPSDHRASALNNLESLPLKYLIKNIYPDVYSLHDMADEAGLPVQTEDGEATGTIVLPQPINATSSLFERYGLYLIDNGNELFLWMGGDAVPALVFDVFGTQDIFDIPIGKQEIPVVENSEFNQRVRNIINQLRNHDDVITYQSLYIVRGASLSEPVNHASAREVATLRLWASSTLVEDKILNNESYREFLQIMKARISK
The following text describes a protein:
Function:
[Neuromedin-U-25]: Ligand for receptors NMUR1 and NMUR2 (By similarity). Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder; [Neuromedin precursor-related peptide 33]: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release although its potency is much lower than that of neuromedin precursor-related peptide 36; [Neuromedin precursor-related peptide 36]: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system.
Subcellular Localization:
Secreted.
Sequence:
MLRTESCRPRSPAGQVAAASPLLLLLLLLAWCAGACRGAPILPQGLQPEQQLQLWNEIDDTCSSFLSIDSQPQASNALEELCFMIMGMLPKPQEQDEKDNTKRFLFHYSKTQKLGKSNVVSSVVHPLLQLVPHLHERRMKRFRVDEEFQSPFASQSRGYFLFRPRNGRRSAGFI
The following text describes a protein:
Function:
Has antibacterial activity.
Subcellular Localization:
Secreted.
Sequence:
MQRLVLLLAISLLFYQDLPVRSEFELDRICGYGTARCRNKCRSQEYKIGRCPNSYACCLRKWDESLLNRTKP
The following text describes a protein:
Function:
Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex.
Subcellular Localization:
Mitochondrion outer membrane; Peripheral membrane protein.
Sequence:
AGMAAALGDEDLDNDDYYSLLNVRREATQEELRASYRRLCMLYHPDKHRDPELKRQAEQLFNLVHQAYEVLSDPQSRAIYDVYGKRGLEVEGWEVVERKRTPAEIREEFERLQRERDERRLQQRTNPKGTISVGVDATDLFDHYEEDYEDMPGGGFPQIEINKMHISQSIEAPLTTTDTAILSGSLSTQNGNGGGNISLALRRVTSAKGWGEVEFGAGDMHGPLFGMKIFRNLTPRCFVTSQCGLQFSSRGVRPGLTTVLARHLDKNTMGYLQWRWGTQSAMNTSIVRDTKTSHFTFALQLGIPHSFMMLSYQYKFQDEDQTKIKGSVKTGFFGTVVEYGAERKISRHSVLGATVSVGVPQGVSLKIKLNRASQTYFFPIHLTDQLLPSAVFYATVGPLVFYLAIHRLIIKPYVRSQKEQELEKHRESAATDIARKKQEAESAVRLMQESVRRIIEAEESRMGLIILNAWYGKFVTDNSRRHDRAKVIDVTVPLQCLVKDSKLILTEASKAGLPGFYDPCVGEEKGLKVLYQFRGVMHQVLSGDTEALRIPKQSHRIDADT
The following text describes a protein:
Function:
Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm. Note=Bipolarly localized.
Sequence:
MSQPELFHDLPLEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIASELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNGSTGISAGYATDIPPHHLGEVIDAVIKRIQMPSCSVDELMEVIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAEIETIRGGREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTGLRVVIELKKEADAKGILNFLYKNTDLQITYNFNMVAIHNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKAKDRHHIVEGLMKALSILDEVIATIRSSSDKRDAKNNLIAKYEFTEPQAEAIVSLQLYRLTNTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKKYADTRRSVIEEKIEEIKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASNGQDFGMKDTDRMLHQFEMNTTDVLLLFTNKGSYIYCPVHQLPDIRWKDMGQHFSNLITIDRDETIVKAIPIKEFDPSAYLLFFTKNGMVKKTELTHYKAQRYSKALVALNLKGEDELIDVHVTNGESQIFMATHLGYGLWFGEDEVNVVGARAAGVKGINLKEDDFVVSGEILQQSDSIVLFTQRGAVKRMSLSEFEKTSRAKRGVVMLRELKKNPHRVVALFACGLEQRLMAETEKGDRKELQTKELRTNDRYSNGSFFFDEEESGKVTAVWRLHTEQ
The following text describes a protein:
Function:
Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
Subcellular Localization:
Nucleus.
Sequence:
MSDFKKSETTIQSGQHVLIRLPSEGLKIVHLQDTGIIGLGKFGSFEVSNILGYPLGTSFEIIEDHKVKPIKSISTLDLTDSDETVQRQELTKMFSDSAENNQNIINIGSKIQKLSKDDIDELKKSGASSNVGQMIIEKMIAGHEGFDKKTIFSQQKYLKRKQQKFLRRFTVDYLGGSELLQYYIEKDLNRVLDLSVETLGLMLTYSNVRPGGKYLIIDETGGVLTYAMMERMNCEGTIVSIHENEHANLIALRYSDYGNELETKTVKSVNWLQFIDPQSERIDWTDLPDEEVKKIKNKSQYKKRRDRALQINEVIQLVEEGNFDAFISVSTLNMSEVLEYVLPKIGGSRPIVVYNQFKESLLEVQQALSGDKRVLAPSIYETRVRPYQTIPGRMHPVMTNRGGGGYILWGTRVIPHDAITAVGKGFAKRKRVETPSKTDTGTVEVQNDQENSA
The following text describes a protein:
Function:
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Sequence:
MALSSSLAGQAAVKLVPFASVVSGNARVSMRKTATKAAPSSSLWYGPDRAKYRGPFSGESPSYLTDEFPGDYGWDTAGLSADPETFAKNRELEVIHCRWAMLGALGCVFPELLARNGVKCGEAVWFKAGAQIFSEGGLDYLGNPSFVHAQSILAIWATQVILMGAVEGYRIAGGPLGEVVDPLYPGGSFDPLGLADDPEAFAELKVKEIKNCRLAMCSMFGIFVQAIVTGKGPLENLADHLADPQVGLK
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
RIIKEKDVKDFKAGPYMATLLNCMLWVFYGLPIVHPNSILVVTINGIGHVIELGHLPHHFLSLLRQEEQEDGSGARYGGSLHGGGGSRRAFGRAHPSEALVGRRHPLRHFWHHHVLLTTHHHESGCEDKERGVHAVAAVGGELPQWHLLDVIRAHPLRHLHHHTQWSWRALCSHPTHPLCHLLPDHTQEAG