lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Potential transcriptional activator that may act by nicking the target promoter. Catalyzes the release of 5-methylcytosine (5-meC) from DNA by a glycosylase/lyase mechanism (By similarity).
Miscellaneous:
MISCELLANEOUS: Although strongly related to DNA glycosylase proteins, it differs from these proteins. The DNA repair function may not exist.
Subcellular Localization:
Nucleus.
Domain:
The DEMETER domain, which is present in proteins of the subfamily, is related to the J-domain, but lacks some important conserved residues.
Sequence:
MLTDGSQHTYQNGETKNSKEHERKCDESAHLQDNSQTTHKKKEKKNSKEKHGIKHSESEHLQDDISQRVTGKGRRRNSKGTPKKLRFNRPRILEDGKKPRNPATTRLRTISNKRRKKDIDSEDEVIPELATPTKESFPKRRKNEKIKRSVARTLNFKQEIVLSCLEFDKICGPIFPRGKKRTTTRRRYDFLCFLLPMPVWKKQSRRSKRRKNMVRWARIASSSKLLEETLPLIVSHPTINGQADASLHIDDTLVRHVVSKQTKKSANNVIEHLNRQITYQKDHGLSSLADVPLHIEDTLIKSASSVLSERPIKKTKDIAKLIKDMGRLKINKKVTTMIKADKKLVTAKVNLDPETIKEWDVLMVNDSPSRSYDDKETEAKWKKEREIFQTRIDLFINRMHRLQGNRKFKQWKGSVVDSVVGVFLTQNTTDYLSSNAFMSVAAKFPVDAREGLSYYIEEPQDAKSSECIILSDESISKVEDHENTAKRKNEKTGIIEDEIVDWNNLRRMYTKEGSRPEMHMDSVNWSDVRLSGQNVLETTIKKRGQFRILSERILKFLNDEVNQNGNIDLEWLRNAPSHLVKRYLLEIEGIGLKSAECVRLLGLKHHAFPVDTNVGRIAVRLGLVPLEPLPNGVQMHQLFEYPSMDSIQKYLWPRLCKLPQETLYELHYQMITFGKVFCTKTIPNCNACPMKSECKYFASAYVSSKVLLESPEEKMHEPNTFMNAHSQDVAVDMTSNINLVEECVSSGCSDQAICYKPLVEFPSSPRAEIPESTDIEDVPFMNLYQSYASVPKIDFDLDALKKSVEDALVISGRMSSSDEEISKALVIPTPENACIPIKPPRKMKYYNRLRTEHVVYVLPDNHELLHDFERRKLDDPSPYLLAIWQPGETSSSFVPPKKKCSSDGSKLCKIKNCSYCWTIREQNSNIFRGTILIPCRTAMRGAFPLNGTYFQTNEVFADHETSLNPIVFRRELCKGLEKRALYCGSTVTSIFKLLDTRRIELCFWTGFLCLRAFDRKQRDPKELVRRLHTPPDERGPKFMSDDDI
The following text describes a protein:
Function:
Probably involved in the biogenesis of the COX complex.
Subcellular Localization:
Membrane. Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MRPDYMGVMFLCSSVMSFNAGIWQIFRRGQKKQLIENHKNIEKSPLTDLPPESATVNECEYRRVKLDGSFDNEGSCLVGPRSIPSYKGAANEDESRGGFLVMTPFEIADTGRFVMVNRGWVPIDAGKHRTMLKQYIGEGFTPAQVRGVLRKEEFLGGSLFWGSSPDNEGPVAADLSWLVVRPWNMAMTYYRRRWGVDHLKESAEKHGAHHYYVEMLEDFSGDDQRIVRGRAWPRRREVDEVTYVHLTPVVHSMYIVFWFSITAGSLYGVLRCWRRQKDIFALRKYVNKQSMQLETRRQVEAQAYMKAVEEVERLKRISTAAAAAQIDIGNPATVTHSEGTASRKKYDSQPSK
The following text describes a protein:
Function:
Required for arbuscular mycorrhiza (AM) development during AM symbiosis with AM fungi (e.g. Glomeromycota intraradices).
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MLMCYKSRMKMFFQKLTNSYSLVWLPLLLILLNKVSVNGVEQKNFYIVFLGGDHPVSREGAVETHLNILSAVKESHVEAKESIVYSYTKSFNAFAAKLSEDEANKLSSMNEVLSVIPNQYRKLHTTRSWDFIGLPLTAKRKLKSEGDTIVALLDTGITPEFQSFKDDGFGPPPAKWKGTCDKYVNFSGCNNKIIGAKYFKLDGRSNPSDILSPIDVEGHGTHTASTAAGNIVPNASLFGLAKGMARGAVHSARLAIYKICWTEDGCADMDILAAFEAAIHDGVDVISVSLGGGNENYAQDSIAIGAFHAMRKGIITVASAGNGGPTMATVVNNAPWIVTVAASGIDRDFQSTIELGSRKNVSGEGVSTFSPKQKQYPLVNGMDAARASSSKEDAKFCDGDSLEPKKVKGKIVYCRYRTWGTDAVVKAIGGIGTIIENDQFVDFAQIFSAPATFVNESTGQAITNYIKSTRSPSAVIHKSQEVKIPAPFVASFSSRGPNPGSQRILKPDITAPGINILAAYTLKTSISGLEGDTQFSEFTLMSGTSMSCPHVSGVAAYVKSFHPDWTPAAIRSAIITTAKPMSQKVNREAEFAFGAGQVNPTRAVNPGLVYDMDDFAYIQFLCHEGYNGSTLSVLIGSSINCTSLLPGIGHDAINYPSMQLNVKRNTDTTIGVFRRRVTNVGPGQTIFNATIKSPKGVEITVKPTSLIFSHTLQKRSFKVVVKAKSMASMKIVSASLIWRSPRYIVRSPIVIYSP
The following text describes a protein:
Function:
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLKEIGSVFSFLTIFPSSNATLESIAKYMYVFPIVGIAIGLLVGSFGFGLSFFLDPLLVSLLVVASIAIVTGIHHADGLADFADGLMVKGTKEKKIQAMKDLSTGSAGIVGLVLYLVGLIITISLTNGFDLFKAILISEILAKFSMVLMASLGNSAASGSNSPFVHLMKDKRKLVAAFIIMLIPVALIGETTGLIMLGVTVALTLFLLGISTRSFGGITGDVIGATNELTRLASLMVFVSI
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
Miscellaneous:
MISCELLANEOUS: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
Domain:
Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.
Sequence:
MGEIFVAGVNFKVAPVEVREKLACSLEETKKVLPILKRETPLEEVMLLSTCNRVEVYAYNFVENSEDLINKLLEIKRLNPSFKRYFFVKRGEEAVYHIFKVASSLDSMVIGEPQIVAQFKEAYRVAKEAGTVGKILNRVYEKALRASKRVRTETGISRSAVSVSYAAVELAKKIFGDLKEAKVLLIGAGEMGELAANYLRRFGAKLHITNRTYERALKLVKELSGNVLRFEELKEYLPLMDIVIVSTGAKDYILKREDFERSVRERHYEPQFVIDIAVPRNVDPEAGNVEGVFLYDIDDLKQVVEENLKERIKEAQRGEIILWDEVKKFMNWYESLKAEPYILELKASVEGKEVSPYIKKLVHRAIKEIKRNPEVADIILRIFKEVEKNEPRRKELSNVYNGTHGA
The following text describes a protein:
Function:
Involved in degradation or processing of the mating pheromones. Its loss causes a persistent response to the pheromones. It may be required for stabilization of enzymes that are essential for zygote formation. May degrade the mating pheromone P-factor.
Subcellular Localization:
Secreted.
Sequence:
MLSLFLKSLFAIIIIELTIIHALPTYTVHWKCSIQQANTSSASSNQTVQPRQHAAPSSDRIKSLPEFKGSLPELYSGYLEANSDKSLFYTYAPAVVDSETFIVWLQGGPGCAGTLGFFSENGPIEISQSSPSPSLNPESWTNFANMLWLDQPFGTGYSQGQAAYTTTIEEASSDFVNALKSFYQKFPHLMKKKLYLVGESYGSIWSANFAEALLSEPSLNINFMGVGIVSGLTADYETQEQITASIWVEHISKLGYYFNNTSSTISEEFKKRNKECQYDSVLNRLTFPTEQYPIWRPEYNFSTSTSLRKREALDGEDIGNVFNSISGCDLYSLSNFLLYLENSCVITYDVSLDCSFNEYNDPLITYLNREDVRSSLHATKASTALTSGEGVFADGCNFDLYKKIVSNNVESVLVEIIPRLTEKYKVSFLAGALDLQILWTGTLLALQNTTWNGWQGFTQSPGSLETTNGFTLDERNLAFTLSNSVGHMAPSKDPQMVREWLENTLLY
The following text describes a protein:
Function:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
Sequence:
MFLEKINQKTGEREWVVAEEDYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDVSQIGGSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLPEKKKVEMNQTFEIVCNHDEFSLWFSNVGKDKSRSYCVCGLHSMLSRQTVYHVNEMFENQKFKDEVDKLSKGLHVATVGEGSFLGLLAAKTAKRVTIIDGNERFRDIFFKYIHYYKLTNVEIIEKVTSLTDSPDIVLAEPFYMSAMNPWNHLRFLYDVEVLKMMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLSFFDEISTKARTATDAIVDEQSLWEYAGIVKGDAVEILRFPIDGRVSSQKCVVNIDNMSSSNAIPMWMEWEFGGINLSTGLLSISSAGVPEWNKGYKQGVYFPITALRNDKSLCLHALFDKSTGDINFQFGKSEDS
The following text describes a protein:
Function:
Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLRAAFTRRTVNQIRAFHGSSIYYAASVFKMPAMSPTMSEGGIVSWKVKPGDTFSAGDPILEVETDKATIDVEAADDGKLWEILVNEGTSGVPVGKPIAFLAEQDDDLSTLEKPSIEDVKQETQAPAPQEKNPEEKTTKKEVKQSAPREVSTGSSVLQKANPNQKLSPAVELLLHENNISNEDAFAKIRASGPKGRILKGDVLAYLGKIDTGVVVELTEFLKSREHLDLSKIMLAEPSKTEESTESKSSKEEKAKVEKPKPKNILSVELTSNLGEDISQSKFKFAFEKSISAAIRQTYASKFPQFAQSPTASSIYDKYDVFDEILSAPVTKNRFEVFDIKYKFYGEESSKNKVSADSFDELLGLSTPVQYLETGSSNVNVSFKIKFDDKLQDSKLFVENFENSLLSQIPANKLKITN
The following text describes a protein:
Function:
Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (By similarity). Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity).
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted.
Sequence:
MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEPGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSAGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRRVPPAPPPEAPGRQNLSGAAAGEALIGAAGFPQHGDTGSVEGAPQPTDNSFTPKCEIVGKDALSALARASTKHCQQEIANVVCLHQAGNLMPKSVPRHCQLAGKVSPGIQWEEVRAQQPVSGPLVRIAYMLVVHGRAVRQLKRLLKAVYHEEHFFYIHVDKRSNYLYREVVELAQHYDNVRVTPWRMVTIWGGASLLRMYLRSMKDLLETPGWTWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTEDPLVAQLRQFYTYTLLPAESFFHTVLENSPACESLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVSRPTFFARKFESTVNQEVLEILDFHLYGSYPPGTPALKAYWENIYDMADGPSGLSDVLLTAYTAFARISLRHAATVSPLATAVCRFEPRGLPSSVHLYFYDDHFQGYLVTQAVQPSAQGPAETLEMWLMPQRLLKPLGHSDQASRLQSLEVGTEWDPKERLFRNFGGLLGPLDEPVAMQRWARGPNLTATVVWIDPTYVVATSYDITVDADTEVTQYKPPLSLPLRPGAWTVRLLQFWEPLGETRFLVLPLTFNHKLPLRKDDASWLHAGPPHNEYMEQSFQGLSGILNLPQPEAVEEAARRHTELTGPALEAWTDGELSSFWSVAGLCAIGPSSCPSLELCRLTSWSSLSPDPKSELGPVKADGRLR
The following text describes a protein:
Function:
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes by the cargo receptor NCOA4 for autophagic degradation and release or iron.
Subcellular Localization:
Autolysosome. Cytoplasm.
Sequence:
STRSSQIRQTYSTRVEADVDHLVVHLQPSYTYLSLGFYLDCVDEALEGVGHFFHRLAEKRKGTEPLLKMQNRRSDHALFQDVQKPSEDEGGKTQDALEAALFMEKNLTQALLDLHALGSARTDPRLCDFLESHFLDGQVKLIKKMGNHLTNFCNVATPRQDWACIFSKGSFSNMTRSLWSPPPLRSSSGVRSSDSSPRLQPLGSFLTTLEPSPQAWTKWKQ
The following text describes a protein:
Function:
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus.
Sequence:
MEPKVIQQCYKTAASTWEYGPKNAFTRQSGSGNNWASGYRTQGTQAESELLDLLQSEAERCDLLKGFLTLQSAAGGTGSGLGSFLTEKLADFYPSSSLLNTVVWPYQSGEVIVQNYNAMLTMASLAEVTHGIFMLQNDAASLICQKLLRIPHPSFDAMNEVLATHLASAFLPVDPNFASRSGRTLDPLGAIWIMKQLHQQSKQQTDTAAFSDPRINSKAMLQTLSITMDKAHDMFSHGAYLHQYERYGIDREFFQEAFLRIDQVTQNYASL
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MLCPAGRILKVQRKFFLHTPQHLSHTSQTEVYGKLACSRLASQLLGGGRRVLLLPCLSPADLGIAEVERRKPEVCAAAAGPHELTPEVAVLRDPACCAMAAIPPDSWQPPNVYLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKIIKAYPSG
The following text describes a protein:
Function:
Forms a tunnel that spans the entire periplasmic space. Could be implicated in lipid transport between the inner membrane and the outer membrane. Binds phospholipids. Required for outer membrane homeostasis. Contributes to membrane integrity.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Domain:
Forms a syringe-like architecture with a central channel.
Sequence:
MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPEVTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDTVFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRVILDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTNNVRFWKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGQPVAPKTAFVLYDDQKSIQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYRIPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNTPAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRTMKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRLDQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Sequence:
MGSESTLPEWAQSLGLWDLWCTDACTVLAHMRRLSLPSALQRKGRSDFENLKANESIGWAVDVNDPRELSAKMLKKNKINLNEISHDSASGLVNRVLNMGVLLTEVCVDTVGDPEKYRIKLSESFPFVKFVVAKKAGSLYPVVSGASIVAKFYCCVQILKLKLGWNKHEHSVFGFPTLVRFSWGTCTPYSKNMVDVLGQLSVFSLHSHSNTLLLQLHHCAA
The following text describes a protein:
Function:
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Sequence:
MAPKTGETVVEKMEVDEAKQDVPATEPAKDLNAIAVENIKEQLAALDKGEEHLITRVLQVLPKTRKQINDNVLYKLVSSHLSSDAQFAEGMLKYLHYTPAADTEVQPMDTSNVKTKSPKKGVKPVFASPESDCYLRLLVLLHLYAQKKNTEALALGENQLTSIYNFDRRTLDGLAAKTLYFLCVIYEREGRLFDHQGFLNSRLRTATLRNFSESQAVLICWLLRCYLINRQYQSAAHLVSKVAFPDNASNNDLARYMYYQGRIKALQLDYNSAAGYFLQAQRKAPQEGAIGFKQAVQKWVVVIGLLQGEIPDRSVFRQPIYRKCLAHYLDLSRGVRDGDVARFNHNLEQFKTQFEADDTLTLIVRLRQNVIKTAIKQISLAYSRIYIKDIAKKLYITNETETEYIVAKAIADGAIDAVITSDVRDGPRYMQSSETADIYRTSEPQAHFDTRIRYCLELHNQAVKALRYPPKKKIAVETIEQAREREQQELEFAKELADEDDDDF
The following text describes a protein:
Function:
Receptor for netrin required for motor axon guidance. Mediates both short- and long-range axon motor repulsion in the developing nervous system upon ligand binding. Also involved in glial migration. While short-range repulsion requires both fra and unc-5, long-range repulsion only requires unc-5.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MAVINKAGNVIALLLVKLQLILLFTLSVSGELPQLDYGSLSASLEEDAIDPLTAMAPFANSLVTEESAQHKNNAELLGNSSEDENVRPQQGSSSSGLGSSGAAGGSGILLEEFNSGKLSPGEASNTLPIFLIEPESVFVVKNRPAVLKCKASHSLQVIFKCSGSSQPPPSTHETHVDPHTGVNMEEVTATIHRDLVDEFFGDGPFKCECHAWSSRGVVKSQAATVHIAYIRKSFNQSPTSLRLELGSRAELRCEPPGGFPEPKLTWHKNNAVITADSEPGITVSAGTLIFRQVALQHMANYSCSAENIAGRRVSDSAVLIVYVNGGWSTWSPWRECKCAGKPSQGRKRSRTCNNPMPLNGGAQCPGPQIQKSADCAACPEDTQIVSPDGFDISSSKRMARWSAWSDWSICSAECIQVRRRKCLTQGQTQISSEAEEAGDLLLGAPGVGMAALIAAAGVGAVGSPSEATGSSSDIIPGYGKSLCAGKDIQTAECRGEQCQIGKDDFDWTLYLGLAFITAVCFAFGTALICCARRGIRTNPHYNMARSVMDADYMPGVVEKKEMRMHIEASNMGYDYVNPGHRYLPGEHIMGMGIGCGGVTEHHYDVPNLSANYTNPIDHLSVDYLSETGESSTADTSNSTFDMNGKLSILNASKSSTYEMLGSAGGQLRLYGGELLLFVPEHAIGKHVKKHVSLLLLSDECSRVSCATESSILCSSVVHSAPRNYSFVKPVILKIPHCLVAPEQWHVHIYHADSEHDELSVNWRRAVSVGEETINTPMFVQLEATHVFIMTEQLGHFTVVAEPRIQQPSIKMKLLAFSQHTPPSNANCSLRIYVVKDFPNSRDICANVEAKLGGSFLGESQVFAFTLNSRNLNIRVRSADVEAAAPYEHAIPYQHILSNNSILHCEFSLRRQDQNSLCVDFGQGSEDDYYTFNIPAHSMSGSAEELASTTNTTISIDRQGNYVNESCVMDFVQLPHATKRLICGALDPPRADERDWRLLAKKLNTDRYIAYFATKASPTEQILNLWECRANSSPGSSSNSVSHTIMALLLTLKEMGRQDVLDIIVETIGPLWI
The following text describes a protein:
Function:
Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MLFLNIFSVAFAASAVQALPTFGKSSVFEKIAAAPAGWELDENAVFDKDVSMMKLRLHLVAQNMPKFHKMAMDIATPGNALYGRHIDQSTINAMIAPKTQSRDLVLQWLSTAGLTNQTTVSARGDSVIVEASIRQVEELLQAQYDAYVHTGLYQGAIRTLEYSLPDALKGHVDIVQPTTFFGLRAMRSNIKQHKEFDESVLKVDGTEAVTGCSGSTITPKCLANLYSFTSAPATLTSGLMGIAGFLEQWPSKSDLTTFMNNYAYFANKAYTYTCTLINGGTCPSSGNGYPGIEANLDVQYARAITSEIPNIYYSVGGSPPIVGGGENQNEPYLEFLDSLLTATTLPNTISISYGDDEATVPLDYADEVCNLFSQLGARGVSILVASGDSGVGTTCTTTGSTKGFTTSFPASCPWVTVVGGTTGNSPEAAWTDGGGGFSSVFGQPSYQSTAVNNWLKTDTTHSSVTKYFNASGRAYPDVAAQATDFVIVASGYAELVDGTSCATPTFSSVIQLINSNRVAAGKAGLGFLNPWLYSTAKSALTDITTGKITGCSGVISGAGFSAVSGWDPATGLGTPNYTKLLAISNST
The following text describes a protein:
Function:
Probable microtubule-associated force-producing protein that is targeted to the forming cell plate during cytokinesis. May play a role in cell division.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, phragmoplast. Note=Localizes in the forming cell plate during cytokinesis.
Sequence:
MANSNTYLTTPTKTPSSRRNQQSQSKMQSHSKDPINAESRSRFEAYNRLQAAAVAFGEKLPIPEIVAIGGQSDGKSSLLEALLGFRFNVREVEMGTRRPLILQMVHDLSALEPRCRFQDEDSEEYGSPIVSATAVADVIRSRTEALLKKTKTAVSPKPIVMRAEYAHCPNLTIIDTPGFVLKAKKGEPETTPDEILSMVKSLASPPHRILLFLQQSSVEWCSSLWLDAVREIDSSFRRTIVVVSKFDNRLKEFSDRGEVDRYLSASGYLGENTRPYFVALPKDRSTISNDEFRRQISQVDTEVIRHLREGVKGGFDEEKFRSCIGFGSLRDFLESELQKRYKEAAPATLALLEERCSEVTDDMLRMDMKIQATSDVAHLRKAAMLYTASISNHVGALIDGAANPAPEQWGKTTEEERGESGIGSWPGVSVDIKPPNAVLKLYGGAAFERVIHEFRCAAYSIECPPVSREKVANILLAHAGRGGGRGVTEASAEIARTAARSWLAPLLDTACDRLAFVLGSLFEIALERNLNQNSEYEKKTENMDGYVGFHAAVRNCYSRFVKNLAKQCKQLVRHHLDSVTSPYSMACYENNYHQGGAFGAYNKFNQASPNSFCFELSDTSRDEPMKDQENIPPEKNNGQETTPGKGGESHITVPETPSPDQPCEIVYGLVKKEIGNGPDGVGARKRMARMVGNRNIEPFRVQNGGLMFANADNGMKSSSAYSEICSSAAQHFARIREVLVERSVTSTLNSGFLTPCRDRLVVALGLDLFAVNDDKFMDMFVAPGAIVVLQNERQQLQKRQKILQSCLTEFKTVARSL
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MMENGEESYVMENDLSRPSHMELSECWVSERPEGIGSFGPVSGKMAEDQAARNSLDRSNANRQQNQWRDKAEHHQQEEEEVACQSGTVAADFSFLPGQSIAVPVPNVEKQRSREENIVAQRASEPQIVKIAEDARAQGPSFGKMEKDNMLICRPQAYNVGQQAKNIDVPTRKDIGSPEQSNQRYWGLFQCSFCNFVFQDLSELVQHQETHNQDKFQGIGQELVQLDQTESTQCEWRRYRCIVCDKTFCKQSSLVTHLRIHTGEKPYSCHVCRRKFNQRTSLTVHLRTHTGEAPFRCNKCNKSFRQQSNLTHHMKSHQRAEELDGGDWSEENRAPGFPLMYLVSEGDEFSNEVWGPKVSLIKGDKEEDSASCKRPFVCGHCFKRFTHQSNLMVHQRIHTGDRSYRCQECGKHFTRRTSLMVHLRGHTGEMPYSCQQCGKSFRQQSNLLYHMKSHAGQNDAAAGSTNKHTVKLSGQLIGPSGQYVERESPRPVSIGNSGVTRVPENQMRVYQCNQCSRWFPSTSSLLLHQKFHVEQPSNVMQSREVQVQYPIGISQPHTFTGNVLISQQEHERSQQQHFRLFSRMDGNNVPGMLNSSAPKVTPQSGSNSGYHKPGSTVEGGPIKGSFQIRGRGRPRKNIWFGSGQTAMGGFGTGKPLHKCWKCPRRFNNKSNLIVHLRIHTGEKPYQCWKCDKRFRQQSNLIQHLRNHEEFRDDDDDVPRQKKGMNKLRQSGKNFHNTAMLSSSGASQTHWSFLPFTDGNLMNQNRQLLEVSPVSQLEDAASHSDCSNDTLGNESAERSYKCGSCFKTFNHKSNLLVHERIHSGDKAYRCQECGKQFSQRTSLMVHLRTHTGEMPYSCQQCRRRFRQQSNLLYHIKTNTVHGQLKCTAENFINSVSRIDSGEDNRICTELDSIPGQAQAWMHLEPSSKTETAPALPQEAIKEEFPCPDCDKVFTHQSNLLVHQRIHSGERAYRCHECNRQFSQRTSLMIHLRTHTGEMPYACQCCGKRFRQQSNLLYHLKSHANQMAGMDVITSAEYTAPKTRGRPRKCDSNDERRAKNIIPRGKRTFKCMECPRRYNLMSNLVAHQRSHDRQPLHTCSDCGEGFLQQSYLTVHKKLHTKGDLPEHVGQFCWKQNQELMIRNPSIEEERGVLYTQHEK
The following text describes a protein:
Function:
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MLTKSSCSSSSSDYTPFISSKPSRCSRRTATITVVSLLGIGIIGLMTYLIVSSINKWRYSYDRLYDVDLLDQIEISPEAEALPNKGEILCWLLTSEKYHDTRALAVNETWLKRCDHGVFFTNKPFEKEQRIPYRTVFSGIPDSYENLFYKSRYAFYYLSEIMRADFDWFVKADDDTFIIVDNLRKYLRTLDPSQPYYVGYRMKPYLENGYNGGGAGYVLKAVELFARHAYDNETICPDDPYEDVGIGRCLANLGIVPHKTVNEHGQQRFNTYHPIRTLEGWSRQADWITDPLITGFDGIARDLISFHHLTPTEMRMFDILLYRVTVDGDCTREKVEFLVEPYSAIMAEVINVNRWIVDNKKDFVPPVCNKCLYSDQLKMFFVGGAMCLKVIENGVKKDVIVNEGELFVLPSRVEHSPQRFEHTIGAVVERTRAQDEFDCVRYFVDDSTTRQYERWFHLNDVVVDLPPVIRAFHASKSHETNAITDESFLQKAPYEPREIELRAPLDLKEFIERNIEELKSGPVTVFGAPEYTSSTIVYGVGDYSMQSGIEEECIVWSVMIVNDEMKLKGGKAKIEVAGELFSINEFDMARVQPEKKFTLSVRDGTVLVIRMPGKR
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
Sequence:
MQPYSRSGGTRRCFYEFQSWMSCVTSADTTSVKQCKPVFEDYEECLHGLKEKEKVRLMVQQLKDNETSKNGVTASELYKASNTIYENLDLIKRE
The following text describes a protein:
Function:
Proton-dependent transporter. May mediate the efflux of lincomycin.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MILETTAKASQQYKVMPIMISLLLAGFIGMFSETALNIALTDLMKELNITAATVQWLTTGYLLVLGILVPVSGLLLQWFTTRQLFTVSLIFSILGTFIAALAPSFSFLLAARIVQALGTGLLLPLMFNTILVIFPPHKRGAAMGTIGLVIMFAPAIGPTFSGLVLEHLNWHWIFWISLPFLVLALVFGIAYMQNVSETTKPKIDVLSIILSTIGFGGIVFGFSNAGEGSGGWSSPTVIVSLIVGVVGLILFSIRQLTMKQPMMNLRAFKYPMFILGVIMVFICMMVILSSMLLLPMYLQGGLVLTAFASGLVLLPGGILNGFMSPVTGRLFDKYGPKWLVIPGFVIVTVVLWFFSNVTTTSTAVLIIILHTCLMIGISMIMMPAQTNGLNQLPREFYPDGTAIMNTLQQMAGAIGTAVAVSIMAAGQHDYMSTVKNPADPAVIPQALTAGVQHAFVFAMIVAIIGLIGAFFMKRVKVDH
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MANVRQNAIESCLVGSIDFGLFDPEKIEMFGACEITENQMMDKGEYVKGGLSDLRMGTQTRERLCDTCGRNQEDCPGHFGYIRLAEPFFHVGFLPHCYKLLQMVCHKCGRVLCSYSDPEIQYIVTHYKGKNRFLKLFEKIASKSGKCQHSPDLKNPNEPDVCLDERFWELVNGDSHSEHVRVKKPCNAAVPAIEQGKDFLIKLKDVSKTEEDYLSAEVVLRIFENISDQDVRLLGFNPKRSHPKWMILKILPVPPLAVRPQVVSPGQSAPSQDDITHKLSDIIICNKRLRAQRSESSTDTAMKETRTLLQYHITTYMINDKPSIERAVTKSGRPLKVISQRLKGKEGHLRGHLSGKRDDYSARSVISPDPSISIDQVGVPEQLAKILTFPEVVTPTNQKWLESIVMKGHDDLGGANFVINDHGTRTDLSCCTDLSTITLSPGYIVERHLRDDDIVIFNRQPSLHKMSMMGHRALIMSGRTFRLNLCDTTPYNADFDGDEMNLHVPQSQTARTEVRHIMAVPKQIISPQANKPVIGLVQDALLGCRLLSKRDTFLTRNQVMNLMMWLPTTKDTILPPPCILKPVQLWSGKQVFSLFLPKISHNSYSQDANKMDQNSIPLADRHVIIRDGNLLAGILDKKTVARSEGSLIHVVINSYNTNIAKDFLNQTQLIVNNWLEHRGFSIGLIDCVVPDFVLQEVKHEIDDVESKVQATIIKAQDGQLERMPGMSYMQSFETEVNNLTNEILSKTYKVINAKIRRDNSLSEMLSAGSKGADTNMSQIIGVVGQQNMEGKRVKFGFNGRTLPHFQKHEYGLVERGFCKNSYIAGLTPPEFLFHAMGGRTGIIDTACKTSDTGYIQRRLVKSMESHHVAYDGTVRNSQNEIVQFIYGGDGLDATGLETQRLALVTLNDEDFMKKYHLATEDPTFGQVEMDDFVLDEFLKTPNKDKFLKEEENRLREYREILQKEIFPNGSNTVVVPVNIARIIESSQRQFDINVHVSKSDLNPLDIISRVDECVNSLIVVKGNDNISRTEQENATLLLRIMLYSHLSAKQCIFEYRLNEQAFKYILGSIKDRFYRSIVAPGEMVGTIAGQSIGEPSTQMTLNTFHFAGISAHDVTLGVPRLNELMNLAKHIRTPSVTVEFERDVAKDEEIVKAVRAQIESASFKKFVIKAEIYYDPNPEETIIEPDTKWINTRIRYGGVEDRELQDLAPWVLRFEINREEMIASNIESISDIVQKIKGMYGDKFFVIGDDDARIIRMQARLKDEQAEFAMDVKFLRETEQQMYKSFTLKGIPGISRVKINSAAEKMFLNPETHGFDKEKVSCLYTEGTAFREILSLDHVDTVHTITNDIYQVCDVLGIEAARHSLSYEMMLIMENAGAALNRRHLDLLADTMTQYGVLYPVSRHGINKTPTGTLMRASYEMTNDVFFDAAVFSEIDYMRDVSSNIIAGKPSRAGTGIVEVLINEDLLPMTKGNNGGEDLIGPATPSMMISPVPQGYVSQDNIVTSPFQDMPTNDIVQSPMSPVSPIESPLNGGALSPMLMDAQSPYLYGAENAASPIMTYKQNYSITMPSPSYQGNAQLLNTTITDHAYSPIAAASPLSPQAMGQSMSPLSPAQQYDPTNFSPAGGFSNTRYNPLSPQTRPMTYSPNNDTPYSPTYEPKKK
The following text describes a protein:
Function:
Required for the maintenance of the bipolar budding pattern. Involved in selecting bud sites at both the distal and proximal poles of daughter cells as well as near previously used division sites on mother cells. The RAX1-RAX2 complex performs the asymmetric localization of the two cortical landmarks, BUD8 and BUD9, at the distal and proximal poles, respectively.
Miscellaneous:
MISCELLANEOUS: Present with 3670 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Bud neck. Bud tip. Note=Before cytokinesis, RAX2 concentrates as a ring at the mother-bud neck and to the tip of the bud. The RAX2 ring splits at cytokinesis, endowing each progeny cell with a RAX2 ring and additional RAX2 localization at the distal bud pole of the newborn daughter cell. The rings persist at the cell cortex for several generations, giving rise to cells decorated by multiple rings.
Sequence:
MFVHRLWTLAFPFLVEISKASQLENIKSLLDIEDNVLPNLNISQNNSNAVQILGGVDALSFYEYTGQQNFTKEIGPETSSHGLVYYSNNTYIQLEDASDDTRIDKITPFGVDSFILSGSGTINNISVGNQILYNLSTLSMTPIFNQSLGAVQAVLADNSSIYFGGNFSYNNGSMTGYSALIWDSISNTTQLLPFGGFGENSSVNSIVKLNNDNILFAGQFYTLDDPSALISSSNNGTNSTSSLNATTLELGQRIPLRYASWDSQGSTTFASDSLVCPNTNEDAWLYPDTSGSLVCNLPYEVSPTKIRLYNSQRSDSEISVFQILTDPSSSIMNLTYLDPLSGELKNCGEFCPLYSRATLLSASQNVSSSMDMITFIDNNKTDVKWTSDFQDFAFVNELPVSSLKFVALNSYGGSVGLSGLELYQDTFSTYANDSLNEYGCSALTNDSSSSTLSSNDWYNGLTGESYIAAKYVPDQNEPIPRVKFYPNIIHPGHYTINMYTPGCLQDNTCSARGIVNVTMWNQQNNTIMKTYLIYQNNDNLKYDQIYSGYLDFSPEIVLEYVSGIYTTNTATVVVADQVNVITVSLDAFNTLSDSSNAKKETLLNGILQYQKSNFTSTRLNETKVGNTTLNLFPVKNYPKNSSLYADIYDNKLVIGGVSNRISIVDLNDDFEVTSSKNQTIQGDVHGITKTNQGLLIFGDILSSNNQSAVFLFNGSFENVFNQSRTVNSALNISLANNDFIVLDNDYVVNASSNALIRNSSSFSLSLWAAGNNGDGDVLFSGAVSHMQYGNLNGSVRFLNENEIEPLNLEGGIVPYLGAYLNESATAYAYEVDSLNKIYFSNEVYPSWNWSSGITQMLYADNQTLLAVSAGSSTTAELSIFDLRNLTMIANETLGSNARINALVNFEKNCSMLVGGDFQMTEPNCTGLCLYNYESKTWSTFLNNTIFGEITQLSFTNSSELIISGLFETKEYQSIRLGSFNLTNSTMIPLLSGSEGKLNSFTVTEDSIVAWNDTSLFIYRNQEWNITSLPGNASSISSVSAIYTDIESNTLNKRGINNVNNGSILLLNGNFNISQYGYLQSLLFDFQKWTPYFISETTNTSNYNPIIFINRDVSTEFNSQSPLANVNITVTSPQSTSSQPPSSSASSESKSKSKKKKIGRGFVVLIGLALALGTVSVLGIAGVILAYVFKDPEGDYKPIKPRIDENEMLDTVPPEKLMKFV