lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage (By similarity). Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs). Is a regulator of stress granule assembly, required for their efficient formation. Required for proper brain development and neocortex lamination.
Subcellular Localization:
Nucleus. Chromosome. Cytoplasm. Cytoplasm, Stress granule. Note=Associates with nuclear chromatin.
Sequence:
MMTSVGTNRARGNWEQPQNQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDGGQTESNEEGKENRDRDRDYSRRRGGPPRRGRGASRGREFRGQENGLDGTKSGGPSGRGTDRGRRGRGRGRGSSGRRGGRFSAQGMGTFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGTRLDFIGVEGSNYPRKFETAPGAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTPSSMENDSSNLDPSQAPSLAQPLVFSNSKQNAISQPASGSTFSHHSMVSMLGKGFGDVGEAKGGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLKSANDSTVHSPFTKRQAFTPSSTMMEVFLQEKPPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKTSLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSSTVSSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSESPSTSSIPSLNETVPAASLLTTANQHSSSLSGLSHTEEIPNTTTTQHSSALSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHSGTPAASFNLPSALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN
The following text describes a protein:
Function:
May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MKRFLFLLLTISLLVMVQIQTGLSGQNDTSQTSSPSASSNMSGGIFLFFVANAIIHLFCFS
The following text describes a protein:
Function:
Essential for mating and meiosis.
Sequence:
MGDSDDFYWNWNNEAVCNWIEQLGFPHKEAFEDYHILGKDIDLLSSNDLRDMGIESVGHRIDILSAIQSMKKQQKDKLQQENKDQELKNIEESYKKLEEKTEHLSDDNVSLEKRVEYLETENTKLVKTLNSLNSEFLQLLRKIAINVKEGRQLTTENSSDTSSMTHPVQPSPSVLGSFDLEVNDSLTNAEKNRKLNVNLTYNEVLCSMLQRYRIDPNTWMSYDLLINYDDKEHAIPMDVKPLQLFRNLQKRGKSPSFVLSRRSC
The following text describes a protein:
Function:
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
Subcellular Localization:
Cell outer membrane.
Sequence:
MIVGLRQKPYLNLRNYKWMSLIYIMRKITGLILLFFATLLPYGKFSYVKAIPWQGEPFFIYSRGMTVSELLKDLGMNYGIPVVISSEINEHFTGKIRDKTPEKILSELAGRYNITWYYDGETLYFYPVQSIKREFISPDGLAANTLVKYLQRGDVLAGKNCAIKAIPHLDTLEVKGVPICIERVKSVSKMLSEQVRHQNQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELNQGNNLPLAGGNQPDGNQASSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEISVTIIDVDAGDISQLGVDWSASASIGGTGVSFNSTFAKNNAEGFSTVIGDTGNFMVRLNALQKNSRARILSQPSVVTLNNIQAVLDKNVTFYTKLQGEKVAKLESVTSGSLLRVTPRMIETEGVQEVLLNLNIQDGQQQASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIESQNKIPLLGDIPLLGGLFRSTDKQSHSVVRLFLIKAVPVNAGE
The following text describes a protein:
Function:
Cadherins are calcium-dependent cell adhesion proteins.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MRRSDPDARGWPVGASLSLPPLLLPPLLLLLGSLWASGTPALSGPEEDDGTFTSGRVKRGWVWNQFFVVEEYTGTEPLYVGKVKCRGRGEELAPPPSLFPFSFFFSSLPDPGLSPTMREAMAKSLELEKQLRILRPLLEGTSVMQVMASDADDPTYGSSARLVYSVLDGEQHFTVDNKTGVIRTAVADLDREKQERYEVVIRATDMAGQLGGLSGSTTVTIVITDVNDNPPRFPQKMYQFSIVETAPIGTAIGRVKAEDSDVGENTDMTYQLKDEGGGDMFKVTTDSNTQEAIITVQKHLDFEAQATHTVVLEALNKFVDPRFVDLGTFRDQAIVRVTVMDVDEPPEFRPPSGLMEVQEDAQIGSIVGVVTALDPDAANRPVRYAIDRDSDLEQIFNIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHSQVSRASLQIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAVGNPHFSLLDIKDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRVCGCDSAGAIQSCNTTAYVMAASLSPGALIALLVCILILVVLVLLILTLKRHHKSHLSSEEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFSEIKGGDGGGGGGGGVGSSSGGGLQAGLPSERPSLPLPQGAPSPELDFSLFRDFISRKVALADADLSVPPYDAFQTYAFEGADSPAASLSSVHTRSSSEQDFSYLSSWGPRFRPLAALYAGHRADEEGDAS
The following text describes a protein:
Function:
Baseplate central spike complex-associated protein involved in the tail assembly.
Subcellular Localization:
Virion. Note=Present in 3 copies in the baseplate.
Sequence:
MSMLQRPGYPNLSVKLFDSYDAWSNNRFVELAATITTLTMRDSLYGRNEGMLQFYDSKNIHTKMDGNEIIQISVANANDINNVKTRIYGCKHFSVSVDSKGDNIIAIELGTIHSIENLKFGRPFFPDAGESIKEMLGVIYQDRTLLTPAINAINAYVPDIPWTSTFENYLSYVREVALAVGSDKFVFVWQDIMGVNMMDYDMMINQEPYPMIVGEPSLIGQFIQELKYPLAYDFVWLTKSNPHKRDPMKNATIYAHSFLDSSIPMITTGKGENSIVVSRSGAYSEMTYRNGYEEAIRLQTMAQYDGYAKCSTIGNFNLTPGVKIIFNDSKNQFKTEFYVDEVIHELSNNNSVTHLYMFTNATKLETIDPVKVKNEFKSDTTTEESSSSNKQ
The following text describes a protein:
Function:
Involved in the biosynthesis of the anthracyclines carminomycin and daunorubicin (daunomycin) which are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers. In vivo, DoxA catalyzes the C-13 hydroxylation of 13-deoxycarminomycin and 13-deoxydaunorubicin to yield 13-dihydrocarminomycin and 13-dihydrodaunorubicin, respectively, as well as the oxidation of these 13-dihydro-anthracyclines to their respective 13-keto forms, carminomycin and daunorubicin. In vitro, it also catalyzes the C-14 hydroxylation of daunorubicin to form doxorubicin (adriamycin), although this strain is not a doxorubicin producer. It can only use NADP. DoxA acts jointly with DnrV.
Miscellaneous:
MISCELLANEOUS: S.peucetius ATCC 29050 produces significant quantities of doxorubicin only when it grows in a highly-buffered doxorubicin production medium. S.peucetius subsp. caesius ATCC 27952, a mutant strain derived from S.peucetius ATCC 29050, is the only organism reported to produce doxorubicin in vivo.
Subcellular Localization:
Cytoplasm.
Sequence:
MAVDPFACPMMTMQRKPEVHDAFREAGPVVEVNAPAGGPAWVITDDALAREVLADPRFVKDPDLAPAAWRGVDDGLDIPVPELRPFTLIAVDGEAHRRLRRIHAPAFNPRRLAERTDRIAAIAGRLLTELADASGRSGKPAELIGGFAYHFPLLVICELLGVPVTDPAMAREAVSVLKALGLGGPQSGGGDGTDPAGGVPDTSALESLLLEAVHSARRNDTPTMTRVLYERAQAEFGSVSDDQLVYMITGLIFAGHDTTGSFLGFLLAEVLAGRLAADADEDAVSRFVEEALRYHPPVPYTLWRFAATEVTIGGVRLPRGAPVLVDIEGTNTDGRHHDAPHAFHPDRPSWRRLTFGDGPHYCIGEQLAQLESRTMIGVLRSRFPEARLAVPYDELRWCRKGAQTARLTELPVWLR
The following text describes a protein:
Function:
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
Subcellular Localization:
Secreted.
Sequence:
MMRNFIVVVNILALTLPFLAAEIQNPDSNCRGEKNDIVYDEQRVLYTPVRSVLNFNQYEPNYYHYRPSLPATASPYMYYPLVVRLLLLRSPAPISKWQSMPNFPQSAGVPYAIPNPSFLAMPTNENQDNTAIPTIDPITPIVSTPVPTMESIVNTVANPEASTVSINTPETTTVPVSSTAA
The following text describes a protein:
Function:
GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis (By similarity).
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8 in vitro. May be involved in the early steps of the plant defense signaling pathway.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.
Sequence:
MAILDTKSSRWIPHNLLFLLLLLLLQSVPYGFGQTQTTPPGTTKTKPNDPVVVVITVLFLVIFFMVFGSIFCRRSNAQFSRSSIFRSTDADAESQVVRIRRLTARGLDAEAIETFPTFLYSEVKAVRIGKGGVECAVCLCEFEDDETLRLMPPCCHVFHADCVDVWLSEHSTCPLCRADLVLNQQGDDDDSTESYSGTDPGTISSSTDPERGMVLESSDAHLLDAVTWSNSNITPRSKSTGLSSWQITGILFPRSHSTGHSLIQPAGNLDRFTLRLPDDVRRQLMKTSRTMGHVALLPQARSSRSGYRSGSVGSERSAFPYGRKSNNNNRRLHSLSFSFSFRSGSVRSTFSGDAPKNLPTSIEAGERSFERLRPDERV
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively. PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions.
Sequence:
MEVPGCSECRVLSIQSHVVRGYVGNKAASFPLQVRQGLVGIKGTVSGIRRACVLGFEVDTVNSVQFSNHTGYNHWKGQVLNAEELQELYEGLKLNGVTHYDYVMTGYNRDASFLARVVDIIQELKQQNPHLVYVCDPVLGDKGKGEGSMYVPEELLPVYRDLVVPVANIITPNQFEAELLTGLKIRTKMEAVQVMDVLHSLGPDTVVITSSDLPASRGPDYLMTLASQRKVDKHGRIHTQRICLELPRVEAVFVGTGDLFAAMLLAWTHHHPNDFKLACEKTVSAMHHILQRTIRSAKALAGPGVKPSYAQLEIRMVQSRKDIESPEVVVIGTDL
The following text describes a protein:
Function:
Regulates ATP-dependent protein translocation into the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Domain:
The J-like region, although related to the J domain does not have co-chaperone activity.
Sequence:
MAARLIAKIVFTSGTVLVRSIQMAYKQALLQAESGMGAAAGSMDVKSKMSPIEARKILGLENVETVSKEDIDKKYNELLTINDPKDGGSEYLQIKISGAKHCLHSALKEGKKI
The following text describes a protein:
Function:
May have an important role in defining the spacing of the nuclear envelope lumen. Essential for centrosome attachment to the nucleus, maintenance of correct ploidy, proper mitosis, association of the centromere cluster with the centrosome and the maintenance of genome stability. Requires direct chromatin binding for inner nuclear membrane targeting.
Subcellular Localization:
Nucleus membrane; Single-pass membrane protein; Nucleoplasmic side.
Sequence:
MSGDYKPNYQSSPSRKRLPLQSKDQASIYKYQTPSTLNLYNNTVNNNSSNNSNNHLLHNSNPNSSYLYDSSKQYSNQINIRNNSNSNSNTNNITSKKASSSYSINNKVDHNSHNNNDDDDIEDDVDINYSTNNASSNILHNRFSNSNKDDSYIDYSTDENPKILKQPQPLYNHLNNQIQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQRNNNNNSNSSNNNNTSTTIKRNNQQIDNNSNKNIISKFIGDPWKNFYYGSNKSLWPFERNNNSNNSSNNNNKVNFKQAIWIFIFSVLFIGCLLGLFSTNFYGIHIYFPSFSTTKTNSPFNSTNNNIQFSNLITKEQLYPIIDEYFKKNEILKSYNKLFEKIENDIKYLSEREQYKDIINEIKEELKLVKLSNMDEDRVNQLISKMINHYNNNENNKQELKELLSKSIEELTKLKSDSKEQLIQISTESMNQLGQLKSESINQLGQVKSESIDKFQSTLKSLSKEEQSKIEREFNHQFNQLNKDADQLLSQHSLKIEKLREEINENQQSSLLKLTQEYKQLEERLKEFSSKLQQSISSSSMDQFESWKLVFIKDIEERINKESSKLTNQYIQLTQQFTKIQSFIKDNPSIDSLTNTIESLEGIKLLIEDILEVYSADKIAKVDYALGLAGASIEYNALHYRVSETYPPIKGSGSGSGSGGANGNSLGLYYYNLATNWIFPQPKPNPPETILDPMVNTGSCWGFYTGNGTIVIRLAKKIAITEVTMEHISSNISHHIDSAPKEFQVFGLINSSDIGQSLGVFTYDTTINRHLQTFKVNKIQSTTTTTTNQDQNDDDNIQEFSHVALRILSNHGYRYTCIYRFRVHGYQIPHPEQEQIQIIQEEQSFKQEEINQQQIEQIEQIEQIEKQQQSDEL
The following text describes a protein:
Function:
Histone chaperone involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with branched poly-ADP-ribose chains, a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions (By similarity). Following recruitment to DNA damage sites, acts as a histone chaperone that mediates histone eviction during DNA repair and promotes recruitment of histone variant MACROH2A1 (By similarity). Also has a nuclease activity: displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage (By similarity). Together with PARP3, promotes the retention of the LIG4-XRCC4 complex on chromatin and accelerate DNA ligation during non-homologous end-joining (NHEJ). Also acts as a negative regulator of cell pluripotency by promoting histone exchange. Required for the embryo implantation during the epithelial to mesenchymal transition in females (By similarity).
Subcellular Localization:
Nucleus. Chromosome. Cytoplasm, cytosol. Note=Localizes to DNA damage sites. Accumulates at single-strand breaks and double-strand breaks via the PBZ-type zinc fingers.
Domain:
The PBZ-type zinc fingers (also named CYR) mediate non-covalent poly-ADP-ribose-binding. Specifically recognizes branched poly-ADP-ribose chains generated by PARP2. Poly-ADP-ribose-binding is dependent on the presence of zinc and promotes its recruitment to DNA damage sites; The KBM (Ku-binding motif) mediates interaction with XRCC5/Ku80 and XRCC6/Ku70 and recruitment to DNA damage sites; The FHA-like domain mediates interaction with XRCC1 and XRCC4; The NAP1L motif is required for the histone chaperone activity.
Sequence:
MSGGFELQPQDGGPRVALAPGETVIGRGPLLGLHRNPCYYQSSEKSQLLPLKTNIWCWLNPGDHFSLLVDKYIFCVLSTHSEMEMECTLRNSQMLDEDDILNEIPKSSSADLPDKTPSAPRRERSTETAKPQAAANNMSFIGESRDLSKQQPNPSERKRILPAWMLTENSSDQNLSVISGGNNVTWESEKERVCKDKTQVNITQPGKKRLISSGSSESTSAKQDTGKKCKNDDQEESIISSKEMPQSFSAAMLHNTEIDNTKTNPQRSKVPVEALGKVSEHKIITKGSSNEDSTARSCSESYSSTQSKSFCDKPQKSHPEPSSNPPSPECVQAKATDSVPNGSEENKVQRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVNITCQDEADDRPECPYGASCYRKNPQHKIEYRHSTFPVRSISDEDDNVGQPNEYNLNDSFIDDEEEEYEPTDEDSDWEPEKEDLEKEDMEGLLKEAKKFMKRKK
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
Miscellaneous:
MISCELLANEOUS: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MDIMHAAVLGILQGLTEILPISSSAHLILVPWLLGWPESGLTFDVGLHVGTLIALCVYFRRDIAYLISDAITGLREGFGSQTSRLPFFIIAGTVPAAIAGKTLEKPIEEFFRGSHTLIALLLIAFGLLLALADTTGPKRWRMDRVDLRGALLIGLAQCLALIPGVSRSGITITAALFLGFTRDTAARFSFLLSLPIVAGAGILKMGELARHGIPAGELAPLLAGMATSAVSGYLGVALLLRLVQRYSLYPFVWYRLLAGGAVLAYLFAR
The following text describes a protein:
Function:
Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MPIILENVSFFYSKNTPLETAALKDVNLRIEKGEFVGILGEKGAGKSTLIKLFNGLLRPESGKVTVDGLSPFSKEVKRKVGMLFQQAADQLFCRTVHEEIAFGPRNFGYSKKETEERVFEALEAVSFDRSMLLRDPFSLSGGEMQRVALAGALALRPDYLVLDEPITGLDPAGKKEILETLKKIKDQGTAVITVTHNLKGFFPLLEKIVLVREGRISFQGSREEYLEAKNVPLPPVTSMMRELKARGLPVNPAIFTVEEALEEILRVKSRLEKEKTEKWSETD
The following text describes a protein:
Function:
Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity). The complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity). Required for gall induction and teliospore formation on seedlings.
Subcellular Localization:
Nucleus.
Domain:
The N-terminal velvet domain contains a NF-kappa-B-like fold and is involved in DNA-binding (By similarity).
Sequence:
MSRPESRSGNASTPQGTSVLKADDGGSGQTPGGSTENSVAYRYVAVQQMTSCRDHIEYQLTVREQPKQSRMCGVGEKADRRPIDPAPIVQLRVVTHDRPIRQSDPVGSASVAPPVERRPGQGAAAPQTPGVRRGLPVTTALGDGWEDKAWYLENPYYFMYAMLCNADTDEELHLLNDGKTRYTSGSCVSCLYHLKDIDGSHQGFFVFPDLSIRVEGRYRLKLCLFETIGHSVHHCKSIYSDPFHVYTAKRFPGMEESTRLSKSFAEQGLKVRVRKHPRSRRRGSKRTKDESDASDETPLARHVSPKRARASDVLPMSGLPMSQPIASSRMPRSMDDRFERADYDRTPSMASAYYDVKGAPPSRHAPWEEEEVLRLRESRAWDPMYDAPSALYSHHAREDRVEDRRLPPRDFADGRYMDGDYPPHTRSAAAPLSSMSARAGPSEYSEHVRSVYLRDDPVRSMHGSPHRLSAALPPLPPPLSKTPSHPALVGRGYPESSASLTPAYSRNYPSVPAPAPAPAPMPMRPAPLLSRSYDHIGQQSSGRIYDDYGPRPNVVAHYSGSYDPRDALARGFSPPSPQPGRRSPYASHHPPTQWRSGPPSPSRPSDYHLGRASAVERGYAAARRSPIPSARGIDTPPEAYAGFESNPFPRRSFGVPDAGRPAATYDAPRAPPADLYAPDEGPPSGRLGGIGFAPSSRERLILPPLPVPSPLSAHRGELTPLGTRDRDREAAYIAMPRDRDQGLAPTERYLSPSGYNPRAGELDQRDREWEWECERERERERERKRGPASPEYRRDFAQATMPSKPSSRGHNQPY
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme. Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Apical cell membrane. Cytoplasm, cytoskeleton, cilium axoneme. Note=Localizes to the apical cell membrane, the basal body and the primary cilium in monociliated node cells (By similarity).
Sequence:
MSTSYSANQYESAFKSQKLQNWTIPKQFKERPSAAEGYTTFIATDRGHLLPGVRTKHRSAWPAFQGTWDLPRRIPPVSMNPTARSQVGQDRLMTWGQMKITTKQAHKGPGDSQAMNRNSHDVENINVDQPAEQSKISIDPDENQPEKPKSQHIQDQSRPASQQAQPIPENLNINQSRPASQRSQKAPSRPATQQNQAEFRPPTHNSRPASQEK
The following text describes a protein:
Function:
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
Subcellular Localization:
Cytoplasm.
Sequence:
MTLMKKFYVTTPIYYVNDVPHLGHAYTTIAADTIARYYRLRDYDVFFLTGTDEHGLKIQKKAEELGISPKELVDRNAERFKKLWEFLKIEYTKFIRTTDPYHVKFVQKVFEECYKRGDIYLGEYEGWYCVGCEEFKSEAELAEDHTCPIHQKKCEYIKEPSYFFRLSKYQDKLLELYEKNPEFIQPDYRRNEIISFVKQGLKDLSVTRPRSRVKWGIPVPFDPEHTIYVWFDALFNYISALEDKVEIYWPADLHLVGKDILRFHTVYWPAFLMSLGYELPKKVFAHGWWTVEGKKMSKTLGNVVDPYEVVQEYGLDEVRYFLLREVPFGQDGDFSKKAILNRINGELANEIGNLYSRVVNMAHKFLGGEVSGARDEEYAKIAQESIKNYENYMEKVNFYKAIEEILKFTSYLNKYVDEKQPWALNKERKKEELQKVLYALVDGLFVLTHLLYPITPNKMKEALQMLGEKEFLKELKPYSKNTYKLGERKILFPKREG
The following text describes a protein:
Function:
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MAPFVSAINSNEDVLTLTLGDDASIQHRLYRLSKGSRVRFMPAACLRGRSIKLEINYPFNKKNFDRLDFTTLHFGVDPTSPNSDPYTDLFFELAGTFDFRYTVEPSDNSILGISKQRKADEGPKQPNKFQGHIIVESEIMLGSRRLTLDNLSIMTMIPPAMGPTIAMIDLQADQSLAQPQEQGGSNSCYSLKNQLRLNPKLFGEDPDKADAKLAEIVAQANKPRDEGGLGLVLIMDVVYNHTSPDSEWLNDHPEAGFNLVNSAFLRAPFVLDRAIALMSKQIGDGTLDLPRRVQSQEDVTRLIDHLEYQILPCAHPAEHLSLALSRSLSLSLSLSLSLSLSLSSNSTQHSDLTSSPFISFKKTMRIVDMDVALHRSSYLVHRNAQWACAWLRNEIKNYNGALDHEYGHANAPSAQCLMPSYLGSAMGSLRGTMAYERLDPTGPCLGDIDEQHPLFSPYFTILAKGRKQDTYDYSPELLEAFDLEHCLVNNGWLFGGDPSTDFVHPTSRAYLRHDVVIWGDCVKMRYGSGPKDSPWLWEHMAEYTRRVCKNFHGVRIDNCHSTPRHVGQYMMDIGRTVRPDLLVVAELFTNSAETDAAFTNQLGISTLIGEYTLEHSLPLMALNALISNGTGTTRGFDELWPDKMNVVADPRKYRPWTGNNKPKSDDEVGISTGLYRFRRVLNQLHHRLTDEHYDQAYVDLKSNDIITVTRHCLKTLQEVTVVARLAFSGDNLGDESAELHLEAPGRVKRVILAARPIAAAKPAGDLQSSKWSYGHSLEYEDFLNVEPKECPNLDITSHETGDRLRVSKFRPGAVLVYTVEPLPAMLNAVTTIENILKQPNHPVEMTAVDLNHALFRCNQEEETEEGKQDGVYYIPNYGPLKFVGLLGLIPLLDEIVASNNLGHPLCDNLRAGPWLLKFLAQHLAKRNSCKPLASILWDAAKVYMDLPIGRRPWAFSQVVSYVYNIVYNYATGRLMSDQAGQCRFVELLTLSSVQLYGLDARRTLDKASLEQDSAQLSMAAGLPHFAAGWMRSWGRDTFIALRGLLMVTKNYEGAKLLILRYAAVVRHGLIPNLFDGGRNPRYNCRDATWWWLQAIKDYCTLVPFGEDILFEVVERRFPSDDPREFEESGTVSMPLCLIMHEVLQKHLHGIEFREWNAGPDIDRDMSPEGFDIAIHVDRETGFIHGGSRWNCGTWMDKMGSSERAGNKGHPATPRDGAAVEIQGLAYSVLSWLAAMPKCPLQPLHTESVGSGEKTWTFEHWADLLKANFSKHFYVPRMDAGDYDSYVVNEELVNRRGIFKDTVGSSAEYTDYQLRPNFPVALAVAPELVSDAHALSALRLAEEVLLGPLGMRTLDPSDWKYRPNYDNSNDTDDYQVAKGFNYHQGPEWLWPIGYFCRAILNFADNKQDTIHRINQFFARHEEHLAHSHWVGLPELCNENGSFCADSCPTQAWSAAAVLDVLYDANMLSNPIQQKSPRRSSSFRAFRLSSV
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Involved in the repression of phenylpropanoid biosynthesis. May compete with MED33B for common binding partners or for occupancy in Mediator.
Subcellular Localization:
Nucleus.
Sequence:
MAPSEFQPSLWESVTSLIRSAQEKNVDPLHWALQLRLTLASAGISLPSPDLAQFLVTHIFWENHSPLSWKLLEKAISVNIVPPLLVLALLSPRVIPNRKLHPAAYRLYMELLKRHAFSFMPLIRAPGYHKTMNSIDDILHLSETFGVQDQEPGSILLAFVFSIVWELLDASLDEEGLLELTSNKRSKWPSSPHDMDLDGLENSVKRNENHDALEKANTEMAIELIQEFLQNKVTSRILHLASQNMESKTIPRGEFHAIVSSGSKLALTSDSALWLPIDLFFEDIMDGTQAAAASAVENLTGLVKALQAANSTSWHDAFLALWLAALRLVQRENLCLRYCFFMHMLEILSEERDPIEGPVPRTDTFLCVLLSVTPLAVANIIEEEESQWIDQTSSSPSNQWKEKKGKCRQGLINSLQQLGDYESLLTPPRSVQSVANQAAAKAIMFISGITNSNGSYENTSMSESASGCCKVRFSLFTLKMFVVMGVYLLCNISCWSLVMKGSPLTPSLTNSLITTPASSLAEIEKMYEVATTGSEDEKIAVASILCGASLFRGWSIQEHVIIFIVTLLSPPAPADLSGSYSHLINSAPFLNVLLVGISPIDCVHIFSLHGVVPLLAGALMPICEAFGSGVPNITWTLPTGELISSHAVFSTAFTLLLRLWRFDHPPLDYVLGDVPPVGPQPSPEYLLLVRNCRLECFGKSPKDRMARRRFSKVIDISVDPIFMDSFPRLKQWYRQHQECMASILSELKTGSPVHHIVDSLLSMMFKKANKGGSQSLTPSSGSSSLSTSGGDDSSDQLKLPAWDILEAAPFVLDAALTACAHGSLSPRELATGLKILADFLPATLGTMVSYFSSEVTRGLWKPVSMNGTDWPSPAANLASVEQQIEKILAATGVDVPRLPADGISAATLPLPLAALVSLTITYKLDKATERFLVLVGPALDSLAAACPWPCMPIVTSLWTQKVKRWSDFLIFSASRTVFHHNRDAVIQLLRSCFTCTLGLTPTSQLCSYGGVGALLGHGFGSRYSGGISTAAPGILYIKVHRSIRDVMFLTEEILSLLMFSVKSIATRELPAGQAEKLKKTKDGSRYGIGQVSLSLAMRRVKLAASLGASLVWISGGLNLVQALIKETLPSWFISVHGEEDELGGMVPMLRGYALAYFAILSSAFAWGVDSSYPASKRRPRVLWLHLEFMVSALEGKISLGCDWATWQAYVTGFVSLMVQCTPAWVLEVDVEVIKRLSKSLRQWNEQDLALALLCAGGLGTMGAATELIVETCHQH
The following text describes a protein:
Function:
May be involved in mitochondrial organization and biogenesis.
Miscellaneous:
MISCELLANEOUS: Present with 1230 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MNSTKRLKMSTTFHDYDLEEPLTSNARPLKNSVITIRVIKSFPYRNVKNIVLHDYDLADKTAKDLFNDVLNKIQNEGSFRPFRNVKFDTLKIYTHAHGSKTVNLVINFDHDDDWTLDIENDKKKLFEYGIENETEISLFNKEDYLRFKENPEEKW
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MHYPNNRTEFVGAPAPTRYQKEQLSPEQELSVIVSALQHVISGENETAPCQGFSSDSTVISAGMPRLDSDTCQVCRIEGCLGCNYFFAPNQRIEKNHQQEEEITSSSNRRRESSPVAKKAEGGGKIRKRKNKKNGYRGVRQRPWGKFAAEIRDPKRATRVWLGTFETAEDAARAYDRAAIGFRGPRAKLNFPFVDYTSSVSSPVAADDIGAKASASASVSATDSVEAEQWNGGGGDCNMEEWMNMMMMMDFGNGDSSDSGNTIADMFQ
The following text describes a protein:
Function:
Component of the glyceraldehyde dehydrogenase which is involved the nonphosphorylated Entner-Doudoroff pathway. Catalyzes the oxidation of D-glyceraldehyde to yield glycerate. When the artificial electron acceptor 2,6-dichlorophenol-indophenol (Cl2Ind) is used, the enzyme shows a broad substrate range (glyceraldehyde-3-phosphate, formaldehyde, acetaldehyde, propionaldehyde and isobutyraldehyde), but is most active with D-glyceraldehyde. It is not known which acceptor is utilized in vivo.
Subcellular Localization:
Cytoplasm.
Sequence:
MTYTGKSIKRLNDDKFITGRSNYIDDIKIPSLYAGFVRSPYPHAIIKRIDATDALKVNGIVAVFSGKDINPMLKGGVGVLSAYVNPSLFRFKERKAFPEDNKVKYVGEPVAIVIGQDKYAVRDAIDRVNVEYEQLKPVIKMEDAEKDEVIVHDELKTNVSYKIPFKAGDIEKAFSQADKVVKVEAINERLIPNPMEPRGILSVYDGNSLSVWYSTQVPHFARSEFARIFGIPETKIRVAMPDVGGAFGSKVHIMAEELAVIASSILLRRPVRWTATRSEEMLASEARSNVFTGEVAVKKDGTVLGIKGKLLLDLGAYLTLTAGIQPTIIPVMIPGPYKVRDLEIESTAVYTTTPPITMYRGASRPEATYIIERIMSTVADELGLDDVTIRERNLIDQLPYTNPFGLRYDTGDYIRVFKDGVAKLEYNELRKWAQQERSKGHRVGVGLAFYLEICSFGPWEYGEIKVDNKGNVLVITGTTPHGQGTETAIAQIVADALQIPIEKIRVVWGDTDIVEGSFGTYGSRSLTIGGSAALKVAERVLDKMKRAAASYFNADVQEIRYENEEFSVKNDPSKKASWDEIASLATTKEPIVEKIYYENDVTFPYGVHVAVVEVDDLGMARVVEYRAYDDIGKVINPALAEAQIHGGGVQGVGQALYEKAIINENGQLSVTYADYYVPTAVEAPRFISYFADKSHPSNYPTGTKGVGEAALIVGPAAIIRAIEDAVGARFTKTPTPPEEIYKAIMSKK