lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating upf1 (By similarity).
Sequence:
MNDSNSSNDSCNTENNTLTATKNSINNTTTTTTTPNNNVNCLKTSGSIKLSASSVPFIPGSSASLPSILSNQYKLAASNNVSNNIMMISTPIISSAQQQQQQVPPPQQTTTTTTATATAITPTPITTSQSTSSSMLNLPLKVGKESIETLFRNRFHPKNNIRETVLSSLQSILIPDLSDTINNTKENIEYFYNMIIDENNYILKLLLLNIINDTKRNLVVYNYNQQHQLPIQNTSSPNTPSSTTTTTTTSTKPSKRGDKERERGRRNKDKINEKQLQQQQLQQLQLQQQLDHEGSSLYLPFSSLLSFIKPDKQQQPQQSQQSQLNEIDQMVRPKSLPKDDNDSDNFNIRVLEYNLKLLIKIYFKVSMYQDSIKTHIFDLYIQINQAISEQQRQLQEKEKESKTSKPIPQPIISLVIPTVLVSIGDIIKYKYATPSPPNLTPTTTTKMEEEERIINTILINEFKKTDVSIIESNLYLFECILSISVSNEPTIVVPNTTTATTATTATTSNTSTAAAATTTTPTLSTSSSSLSPPASTQSSLSLSSSSSAVIAPTTVGYIFKFNKELFRKLIALVYSTVVQHQITLSTVFTTLVLKGYLNEDQIQKLLNITLFKLSDPSEQVKLSYLTLLSKMVSYFDLNHQKNLNHKVNDISLPYKLLIMGSTSQPFFNGQIFKKIFDWIMGIGKDQPSFDSLTKYLIDLFDSFNVISILFNEQNKILSQQYLAAQSTMITPPLSLHQIDDRRKFETLISKSDELIWFWTVWECSKFCIANRLKSPYGSAFQTFEIFEKLLLQLNKDRRDFKKIKILLHFMESMEKLIFSTVNGSVLVQSLNNKETQFFRHNVRVCEDWFSRIRVNLLKASILSSSTPDIIRHASLRVQDIQANRFVLDSNTAHFELEFCILHLANALQQLNETESLQGLSNWSDINLNNSDNNNNNNNKNNNNNNNSTFFNNGNINKYTLKLPWMKGVILRSKQKFEESISSLLSVPPMLESNSISFPFVLEQIIKSYLDISNFTEVEQFLQNYQNQIQQQSNSLIIYKDTFIKTLGSFYRGEMEEAHAFAKRTESQNHILQREQLGLGLLGNQIMTDELLLSIMVNQKDLFNNTNIINNNNSGGSSSGTATATAVTTTTTTTTTTTTTTTTTTNTNNDIIGFSNNINSMLKLTKNNILKALNYLGLESNVQTFQYLTQLKIMDEIENGVYNSRVVPINNQIGFLERLRRVRGHISNTKQRSDILLSNIPLTEKMIKLSRKFENYKFSSKLLDTILESHSSSYYLERCKLKYLNGKQTEATLDLIKYAHRDITIPSSSTTTTTTTTTTTPPSTSSNTATTTNNINIDELSTQKFKVYTEIIKYLNSNPSIITELSSSNYSIPQEQLNPEYYFKKATLTKPENSKLWITYADWILNEKSNISEQNDEESLNGGGSGGNENSSNEMLRLKNTNTNELKTAVEAYFQFLKYSMLDGNSNGGLNIRATLKILNILVCSGNKLVETFERCLNELTSTRPFTIIIPQLFARLSHPDTFVQKYVVEILNRIGRDNPNKIVYQTIVGSLNFTNTNNNNNSSCAAATTDDGLDIELLQKQYPNYLQILNIKENLLKHSELLVKETETLIYQLGKLTTLWDDNWQYFIEQIQGWVYINTKQWNDDYQQLKATIKNPTILKHTLKKKNQELLQPIYEKLKRLTAATVLSVCKTPHEKWFTKCHFETINKTIRAFEKQNKPTSPFDVLHDLIAEFQQYRLISLSLSSVNPSLALFRPTITQMPGTDLNYFNINHIHHHHHHHNHHGNNNNQHSTSSGNLPIQNQVTIQLIKPTIYLLPTKTKPKKMAMLGSDGNLYYYLLKGREDLHLDERIMQLLNVVDQLLMNDKKPTLKLLRTRNYSVIPLSQSSGLIQWVEGAVPLFSIYKNWYKNDQVYKQQQQQQQQLQQQQQQQQQQQQQQPQPQQQPQQQPQQQPQQQPQPQQNSTTTSNIVNKPIIARPVDIFYAKITPLLEKAGLNFMTPRSEWPKEILIQVLNELMQETPKWILQRELWFSSSSSSELFLKTQSYSRSLALMSVIGYMIGLGDRHLDNILLDLKTGEIVHIDYNICFEKGAELKIPERVPFRMTQIFEYALGLTGVQGTFRETSIQIMHLLRKNKDILLNLLETFIYDPLFDWKHSNKQTNNNNNNNNNNNMNQAAGEQESIEKKQSSNNSSNPIISTPTKLQQQQKLPNSPLSISSNNTNSTNNNNNNNNNNNNNNNNNNNNNNKDQDSDSSQSQEDEDNNVVEGEGGEGGEGDIDELNLVQDSSNGKDAFKSIQGLTVVNQVRLKLEGTEKKLSIPDQIDLIIRESMNVENLSSTYEGWSPWV
The following text describes a protein:
Function:
Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as a ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
Sequence:
MMKELSLNIPLLKALEHMHRYARFMKQLVTNTKGSMIEDVDSLHHCSADTTRILQKYTTFGEMDTHRLTFLKSPSNMGHNKTQSGTDPGKHGHAKCHFVAIDIFTGKKLEDIVPSSHNYDVKDGFAKGKDLVLSVMSAMGEEQICGINDIGPK
The following text describes a protein:
Function:
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
Sequence:
MNLGLFSVNLYKPTNFGHYPPSFLSSPAAPFAASNEGPKLAAPLRPQSPIESRAMAITFSDLHTESGLKSLDAFLSGKTYISGDQLTKDDIKVYAAVIEKPGGSFPNAGKWYECVSSHLAASFPGKAAGVRVGGKGAPVEEVKGAAPAGDDDDLDLFGEETEEDQKAAEEREAAKKSSAKKKESGKSSVLLDVKPWDDETDMKKLEEAVRSVEMPGLFWGASKLVPVGYGIKKLQIMMTIVDDLVSVDTLIEEHLQAEPINEYVQSCDIVAFNKI
The following text describes a protein:
Function:
Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. Plays a role in neuronal migration.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MSEFKLQHLVAELLNCLGAKNPPEKLVEALQKSISSSTGKECSGSQVAIQSYVQRIAEDLKNSEPFLLKFEDLKQKNVDCLGPYVQLLYHISQDSSVRSLLGKMDKHSEQKTEITRDDLPQVRNRLRREALKRSQKECSSSSILNTSTNLPRASTPSVTSWVQRRPTLSCDFSTQSCSTICPAVPVVSQENILIKDLLVVLIGIPGCYIEAEELNDPYAPRTFKINDNVPLPLQELVKQILPIASHYSLIQRFAEEKLRFEFGQVNNALAEEMSAILKEHLIYVTQLQDEFEADNLNLQKLWFYVQKRLQPFGITANIATKISKSDAKGGKVLSLLHDHIIGSIGDERTQQRCVSLMEAACVPYMKMLGMWIYRGIISDPISEFLVKDNEVIQKEDMPVDYSADYWDKKYSIEREKIPKFLEPVSDIILKAGKYLNVIRQCGKPVKNKIRPILYKIEEKHYIEAIENAYKFASQTLLELVVKEKDLLGRLRSVKHYFLLDQGDFIVTFLTLCEKELSKDVGDVIQGRIESLMDLALRLSSAVSDPYKDDLRTELLPYDLQFQMMKILTIQTNMEQDFRTAYERQKLLVIDSFSFSYEVHWPLSLILNRKSLACYQMIFRHLFYCKYVERMICQVWKCNKVAKKFHFDDAQHYRAAFALRQRMLHCVQNLEYHMMVEVIEPHWCLFLQKISKVNNVDEILFCHRDFLDSCLKDCMLTIPPILRTVTKLLAICVDFCQFMQNEKAFQDSASHASTAPSFKERISLFDVQFSVALVNLLDQINNLNKDSSEHDRLFNLLYRLDFNSFYSGDLMKKDFGTITIESSG
The following text describes a protein:
Function:
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
Subcellular Localization:
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Sequence:
MKYIFAPPANKGLQQLNHALFESSHTLPALKIPAHASGIAMETLRSHILVAPRLRTIVDDPTDKKWRLLLLDPSMEASEINDLPNPLKEFALKHEAKLVKHTIELKYDYWTSDQVLRSILPDEMETPGAFETVGHIAHLNLRDRYQPFKHIIGQVILDKSSHIKTVVNKLDNIDHTFRFFQMEILAGINDMNAKLKEGGCFFHFDFSKVYWNSRLQGEHDRIIKLFGQNDLICDVFAGVGPFALPAAKHKRCVVFANDLNPQSFKYLMENIKLNKLETRILPFNMDGRQFIKQSLEDLNNPAIWNKITKQKPTSNDKKRNRKVESPTVAPLTDQPAISGIRHFKHYVMNLPATAIEFLDAFHGLYSGMRDVIMDSDLPTIHCHCFSNAKDVKADVIERVERVIGMPLGSNLIMVHSVRTVAPNKDMLCISFRLPSALAFAEPKILGKRKGLETEENLVSQSDVSKSSDNILEKDT
The following text describes a protein:
Function:
Functions as a protein modifier covalently attached to lysine residues of substrate proteins, as well as a sulfur carrier in tRNA thiolation. The protein modification process is termed sampylation and involves the formation of an isopeptide bond between the SAMP2 C-terminal glycine carboxylate and the epsilon-amino group of lysine residues on target proteins. Is able to form polymeric chains with itself at Lys-58, similar to ubiquitin and other ubiquitin-like proteins. May serve as a proteolytic signal in the cell to target proteins for degradation by proteasomes.
Sequence:
MNVTVEVVGEETSEVAVDDDGTYADLVRAVDLSPHEVTVLVDGRPVPEDQSVEVDRVKVLRLIKGG
The following text describes a protein:
Function:
Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MGTRGLQGLGGRPQGRGCLLLAVAGATSLVTLLLAVPITVLAVLALVPQDQGRQVEKIVIGSGAQAQKGLDNKPSCISPSPSSLSETPDPRLHPQRSYSSRNLDPTSQRPVAQPSREASAWVTTLSPAVDSILDPGVQQLPLGEPETDFSPELPAAHLIGAWMSGQGLSWEASQEEAFLRSGAQFSRTHGLALPQDGVYYLYCHVGYRGRTPPAGRSRARLFTLRSALYRAGGAYGRGSPELLLEGAETVTPVVDPIGYGSLWYTSVGFGGLAQLRSGERIYVNISHPDMVDYRRGKTFFGAVMVG
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MAVAQAKLVKETEDCSLLPLVHDIIKCMDKDSPDVNQELTKLKTKIQETREQISNMSGIDCSPPEQQQQLATLREQVRTKNQLLQKYKGLCMFDVPKAS
The following text describes a protein:
Function:
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
Sequence:
MRAELAVYFIAGTQDIVRGTLPSVLEEALKGGITCFQYREKGAGSLQTASERKEMALECQKLCAKYQVPFIINDDVALALEIGADGIHVGQTDEAIRQVIASCSGKMKIGLSVHSVSEAKEAERLGAVDYIGVGPIFPTISKADAEPVSGTAILEEIRRAGITIPIVGIGGINETNSAEVLTAGADGVSVISAITQSDDCHSVIKQLKNPGSPS
The following text describes a protein:
Function:
May be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity).
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MDMMLLVQGACCSNQWLAAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITGSADVLFSCWYLVLTLSSFTSIFYLKNAILQ
The following text describes a protein:
Function:
Possible regulatory or functional link with the histocompatibility cluster.
Sequence:
MPQQRRKVAFSGKKKKDQMLQKRNTKGPPKYLRSTQESYEDSDVPETTRKLMEQPFARGGNRNKNVNRYNLQFYQEGKKELEQMKQEGFKPFEKLSPAQREVDDRYFAGCDFPVRPPWTLTESKEELDRTENRYFKEYVDELQKKQRAGDSKELSLFELNLETWRQLWRVLEFSDILLIIVDVRYATLMFPPSLYDYIINTLKKHAIVVFNKVDLVEPHAVVAWRQYFRDRYPQLPVVLFASFLPRSRKGSQRGPQAHRRSMEGVYNIYKECQRYVQGEVDLTTWEQKIREDMRSDQLDILDEISTAVEGELKISSSIDTTPHEHVKYHSGVLTIGCIGFPNVGKSSLINALKGRKVVSVSRTPGHTKHFQTIFLTPLVRLCDCPGLVFPSSTPKSLQVLLGSFPISQLAVPYRSLKFLGEHLNLPQLLRLHLPEDYDEWSAVAISDAWAYKRGFLTAKAARPDRYRAANHILRMCLAGQQMLVLQFYPPGFEERREHWLQHPDVGEVKKYQQVELDEPESETNGDTSSVCSDTADSEDEDEDSSNDETNADEEECGIREDAPRSRNVFALLEDD
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MCILPCLTVILFLQSSVVLGEMFTALADLEGLVLTELELVKQLDTYIQEEENKLKLLRGHMEEYENMYQEASADVSKYLANPVNAYLLVKSLTSDWKKIEGVMSQNFGSAFLKNITQHRSDLRFPSDEDLNGAAVALMRLQDTYKLDTHALAKGELLGKKYSRQLTAGDCWELGRQSYNNGDHYHTVLWMGEALNKWDDESNKTAAREDILDYLSFSTFKQGNVKEALQLTNELLKIVPYHQRAIGNKKHYEDVLRKEGILLPIEMILTKPFNTANLKLKKPVDNLEERDKYEKLCRGEKLMDPKIEGHLRCRYITNNVPFFFIQPIKMEEALLKPMIVVYHDVMSDDEIETVKKMAKPRFKRATIRNSKTGELEPANYRISKSAWLKSEEHDHILKVTRRVGDITGLDMSTAEDLQVVNYGIGGHYEPHFDYARTETTEAFKELGWGNRIATWLFYMSDVEAGGATVFPPTGAAVWPRKGSAAFWYNLYPNGKGNELTRHAACPVLSGSKWVSNRWIHEHRQEFRRPCGLTFDAEM
The following text describes a protein:
Function:
May be involved in free fatty acids export.
Miscellaneous:
MISCELLANEOUS: For all TMEM14 proteins, 4 hydrophobic alpha-helical domains are predicted. However, NMR structure determination of the human TMEM14A showed that only 3 of these helices are membrane-spaning while the amphiphilic N-terminal helix is probably located at the lipid micelle-water interface.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHDFCFTIPYGILLIVGGFIGYLKKGSIASLAGGAGTGLLVVLAGFISLKAFEKKKTSLLATLLETVIAAALTFVMGQRFLQTQKIMPAALVAGISALMTCFYVYKIATGGNHIPPKAE
The following text describes a protein:
Function:
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MSGIAGTSQDTSVAASASSSSTRPAAASSSIAPPSPSLTTAPVKEQEQDDDDDQENDDEEEEEEGTAAITGADGLTAKQRKKKKSKAAAKLRKKLGLGGSPTDASEGKLLASGSSREGKISDEVVSQVQRAVQAEHGSVAANAVTKANLAKVMAMMNLERDAMLKSQDSKQKAQKAIADHKFWKTQPVMKPTDAPVVKSDQEGSIEASVPPEQVRQEPYPLPADFEWVMIDVDNEGELKEVYDLLSANYVEDDDATFRFDYSPEFLHWVLKHPGYQKTWHIGVRVASTKKLVAFISGIPHELRVREKSYQSTEINFLCVHKKLRSKRLAPVLIKEVTRQCHLTGVFHAIYTVGSVLPTPVSCSRYYHRTINAKKLAEIGFSAIPHNMSMEAHVKRFELPAKTNLPGLREMERRDVAQVGKLMRRYMRRFDMAPRFSDHEVEHILLSGRGEACQGGRGRKGQVTWTYVVENSEGRITDMFAFYSLPSSILDSDKHQSLNAAYLFYYATDVVFQGDCDCDSDSSGVCDAETGRASTSQPSSERAVALAAGKAAWQCNSLTNLTSCELADEARVAAWDSEPAHIKTALKTRLNLLINTLLIIARDHDFDVVNCVTVMDNALFLQQQKFGPGDGFLRFYLFNWRTKPVAGGMGARPGEAELDPVQAYARSMAKRAAHTDDDDVKRLAEQLIRNAAINPAEVGSGNGIVMV
The following text describes a protein:
Function:
Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity).
Subcellular Localization:
Nucleus.
Domain:
The ARID domain mediates the interaction with DNA.
Sequence:
MERSALQWVGAPCGSHGPYVFYRAFRFQRRGGGRARVLSLGDFFFVRCRAEEPACIAELQLLWEERTSRQLLSSAKLYFLPEDTPQGRTSDHGEDEVIAVSEKVTVKLEDLAKWAQSDFSKWKCGFRAEPVKPMDVGKNGQKEALMRYRQSTLNSGLNFKDILKEKADLGEDDEDSNLLILSYPQYCRYRSMLKRIQDKPSSILTDQFVLALGGIAVTSKNPQIFYCRDTFDHPTLIENESICDEFAPNLKGRPRKKKPCPQRRDSLNGIKDSNNNSESKAVAKVKCEAKSALPKPKSNNSNCKKGSSEDKSKIAVGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPVKPRKQDNSSQEGEAKTKVSGTKRIKNENQKSKKEKDNAQKPQDASEVSSEQEKDQESADQKNFTEHPTAGETKQPNQGPPPLLPEAARPLPMEKIDVTENSSSSEKAKEEVPHLSSFPSLSMPPDEDTVLDATVTKRLHSSADTQEDTKPERRIHKAFTESLENEPPEMPFSTFPVQLPTQSDMEDDKLPEMADYIANCTVKVDQLGNEDIHNALKQTPKVLVVQNFDMFKEKELPGSMSDDSTFGYTPLLYSKGNPGIMSPLAKKKLLSQVSGAALSCSYPYGSPPPLISKKKLNSRDELSSSLSQGPHVPNSDPIAINRPSVIQHVQSFKSKEERKSINDVFKHDMLSKVDPQRCDFSQHCLSSLAESYVPKTDIQDCKDKMTEKRALQHSRVPTFLADFYSSPHLHNLFRHTEHHLNNEQTSKYLPRDMFRESENISTFTQHKHQEKLNLNYHPSLHQQEKKATVEASSDDQPTDLSLPKSIHKQTAKAPGPGLSHSSMAQQEGKGVSLFQAASSQAVSLDCNPKACRVSPMAMTAPKKHSELLHRSGKQQAQRLENLRKMEGMVHPIISRRMSPQNIGAARPLKRGLEELDKVISEKKVRAVSPLHLPKETSVKEKVPDAEGEGSKSLHGLHSGSVLESHKFPLSAPIFPGLYPGTLCTGLNNRLPPGYSHPLQYLKNQTVLSPLMQPLALHSLMVQRQFLTSPANSQQLYRHLATATPVGSSYGDLLHNSIYPLAAINPQAAFPPSQLSSVHPSTKL
The following text describes a protein:
Function:
TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.
Subcellular Localization:
Nucleus.
Sequence:
MDPIMKLLEDDEEDESMHSGADVEAFTAALNREVEGSASSSSAAGGSSFQPLDRAAGTLPQKSNPVVNNSHGQWQGSVKNDIGNQESQQHEEKHLYCKKEKSSGPEAIPIDADNKQLHSNTQIECLQLKVKQEPGNNAQQSTVGQQQPMQQIKSQQPPGTNQSNSPAMVGKPPVVTFHMLIPILRRYLDKDRDIQVQSIFAKLRKNEVSKEHFLKVIRTIVGDKLLKQAASQYQMQAAQAQRNPLANPSNYSISSQVPDQQNEGPRLPQFRPSSSGQLQSNMGYAASEGNLQKPNETGNMSDRKGLQMLQSRPPNIHSIPMQATQDHVQRPHTFLPALGANSIHSRQFPHSVGGPIAPLRPQMTDSSQRGQSVQGGVASVLSSVATGPALQNNQTSQQQPNKEQKTNSFTPTVHMNKETANQPSESAQSSFAALNAKQVNPGLVSSKVGGVLENQSSMLATPKPLTTTSSSQPHPSYGTPSELNMQIQPSTQAPPSGAASKTPQKKPSAGQKKPLEAIGSSPLPSGKKQKGSGGFHDQSIDQLNDVTAVSGVNLREEEEQLFSAPKEESRVSEAARKVVQLEEERLILQKGPLTKKLAEIMRKYNLKSIGCDVERCLSMCVEERLRGFISNTIRLSKQRVDVEKSRHHYYPLSSDVRSHILRVNREAREQWDRKLVVDANRIRKQSDGDDNSVISSEKDKAESRGTSKHAKTYKEEDDKMRTTAANAAVRVAAGGDDMLSKWQLLAEKNKLRGEGGDSYSDSLPGTMSPHKLSPKAGKGSREQHEIEKRGYFSILGPGGVRRSAHMKVVRSITVKDVVAALEREHQMSKSSLLFRLHGRQPTEPAAK
The following text describes a protein:
Function:
Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici and to the pathogenic bacteria Pseudomonas syringae.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MNHHHYSLVIFHLILFLSLDFPTLSHRFSPPLQNLTLYGDAFFRDRTISLTQQQPCFPSVTTPPSKPSSSGIGRALYVYPIKFLEPSTNTTASFSCRFSFSIIASPSCPFGDGFAFLITSNADSFVFSNGFLGLPNPDDSFIAVEFDTRFDPVHGDINDNHVGIDVSSIFSVSSVDAISKGFDLKSGKKMMAWIEYSDVLKLIRVWVGYSRVKPTSPVLSTQIDLSGKVKEYMHVGFSASNAGIGSALHIVERWKFRTFGSHSDAIQEEEEEKDEECLVCSGEVSENPKEIHRKGFNFRVTVVGLKIPVWSLLPGLAAIVILVAFIVFSLICGKKRISEEADSNSGLVRMPGRLSLAEIKSATSGFNENAIVGQGASATVYRGSIPSIGSVAVKRFDREHWPQCNRNPFTTEFTTMTGYLRHKNLVQFQGWCSEGTETALVFEYLPNGSLSEFLHKKPSSDPSEEIIVLSWKQRVNIILGVASALTYLHEECERQIIHRDVKTCNIMLDAEFNAKLGDFGLAEIYEHSALLAGRAATLPAGTMGYLAPEYVYTGVPSEKTDVYSFGVVVLEVCTGRRPVGDDGAVLVDLMWSHWETGKVLDGADIMLREEFDAEEMERVLMVGMVCAHPDSEKRPRVKDAVRIIRGEAPLPVLPARRPLLRIRPANEAEEMIVDGLVGEDLPWMTPKSHFS
The following text describes a protein:
Function:
Involved in the regulation of sugars and amino acids metabolisms during the night period.
Subcellular Localization:
Mitochondrion.
Sequence:
MMWKNIAGLSKAAAAARTHGSRRCFSTAIPGPCIVHKRGADILHDPWFNKDTGFPLTERDRLGIRGLLPPRVMTCVQQCDRFIESFRSLENNTKGEPENVVALAKWRMLNRLHDRNETLYYRVLIDNIKDFAPIIYTPTVGLVCQNYSGLYRRPRGMYFSAKDKGEMMSMIYNWPAPQVDMIVITDGSRILGLGDLGVQGIGIPIGKLDMYVAAAGINPQRVLPIMLDVGTNNEKLLQNDLYLGVRQPRLEGEEYLEIIDEFMEAAFTRWPKAVVQFEDFQAKWAFGTLERYRKKFCMFNDDVQGTAGVALAGLLGTVRAQGRPISDFVNQKIVVVGAGSAGLGVTKMAVQAVARMAGISESEATKNFYLIDKDGLVTTERTKLDPGAVLFAKNPAEIREGASIVEVVKKVRPHVLLGLSGVGGIFNEEVLKAMRESDSCKPAIFAMSNPTLNAECTAADAFKHAGGNIVFASGSPFENVELENGKVGHVNQANNMYLFPGIGLGTLLSGARIVTDGMLQAASECLASYMTDEEVQKGILYPSINNIRHITAEVGAAVLRAAVTDDIAEGHGDVGPKDLSHMSKEDTVNYITRNMWFPVYSPLVHEK
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.
Sequence:
ENAPGGNGGPCGRAEERAAVPPTPGCPHPLVPPTPWRSPLLSPPPSLAAPSPYPPPHPTRRCHVPVGCPRPFVLYNGCGGWHHPRAGHGATLRPAPEAAFGRGPALGCPVPAAEGARGQRGPAGAGGEGSGAVAAGQRAAGAVLPAALDPGGRDPALPPRHGFRLVASLTASLPQDPVPSKAASVQPPAQKLRCELRRLLVERGESWSEELERDVPRTWQRHGDLVLLSEDSFSAALWAKLGPVLWETVAAALGAQRLAKRGRVLPDKMRSPTVTLLLGHNSWVEHVDNGIRYTFDVTKCMFSPGNITEKLRVASMQCSGEVLVDLYAGIGYFTLPYLVHAAAAFAHACEWNPHALEALRRNLALNGVQDRCQIHAGDSRQLQLRDVADRVNLGLIPSSEEGWPVACRVLKKSTGGVLHIHHNVESRPLPPALKDEQRLPEESSSEQKDEEHRGSEEMESGVQEVLAARVRPEWWSWAEAAAVRIRGLLTELHSQPWQTHILHIEAVKSYAPHVHHIVLDLECRPTPPA
The following text describes a protein:
Function:
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MMRIPAAPRFASKASTSSRLLVPSRRATTAATSSAHTLNPAGTVTTLPNKLRVATESIPGHFHAVGVYIDAGSRYESQRTSGVSHLLDRLAFKSTDKHTDAQMTTLIDSLGSQVTCASSRETIMYQSTVFPQSLPLAFELISSTIRHPLLLPEELLAQKEAAAYEIREIWAKPELILPEILHTVAFRDNTLGMPLLCPESQLGVLGEEEVRGFMRDWYRPERMVVAGVGMPHEELVMLAEKFFGDMPATTTSPGSLHPSVTQAQQPLGSKSFATASALPVSQDYTDLAHAKAQYTGGELYMEKPEEEFVHIHIGFEGLGIHDPDIYALATLQTLLGGGGSFSAGGPGKGMYTRLYTKVLNQYHAVDFCAAFHHCYADSGLFGISASVYPQFASRIVDVMAGQLHALTGPMFGGVEEKEVRRAKNMLKSTLVMALESRLTAVEDLGRQVQIHGHKVPVEDMCAKIDALTMADLHRVANRILRPGNSSEGRVNYGLGSGKATVVAQGPGLGALGDVRRILKDRWVLGV
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane; Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAFLNMEQQTWAFTFGILGNIISLMVFLSPLPTFYRVYRKKSTEGFQSTPYVVTLFSCMLWIFYALLKTGAVLLVTINGVGCVIETVYIAMYLVYAPRAARVLTAKMLLGLNVGVFGLVSLVTMVLSNGNLRVHVLGWICVSVALSVFAAPLSIMRQVIRTKSVEFMPFSLSFFLVLSAVIWFAYGALKKDVFVAFPNVLGFVFGLAQMALYMAYRNRKPAAAVVMVEEVKLPEHVKEVAAAPVAHEGRASCGAEVHPIDILPVEPPAAAVAAQDPQVAVAIDVEPVTCAAAAGRVDGDGLVAPELAMIKPDTAIAVEV
The following text describes a protein:
Function:
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Sequence:
MYRLAVSAKRKVLLNPKTFAVYFFAIFFTFLLAYHQRLGQQLGQHTHMSRIVNMQSAVQEQNVPQKETPQVEKENNVGKEEQKDVLKEIPKVSNQEKVEEVCSRPPEEVKTDFNTFDLFESVVASSKALPQSSRKARIEKLKVYVLPFTHVDPGWLETFESYTKRTNQILDNMHEFMMKNEKMRFMWAEFVFFERWWSLKDEKVREDVKKLVSEGRLELATGSWVMTDEANPYFPVSVDNIVEGFQFINQHFGIKPQTIWTNDPFGYSNSVPYLFKKSGVRRNVINRIHHRIKQTLQGQQAIPFKWRQYFDKAGEDDVLTQVLPYTHYDVLNSCGSDASVCCEFDFKRITHWSCPGPKPVNINDQNVVAKADKLVGQLERMSEMYKAPVILMMHGDDFRFDMIEEWHQQHDNFLPVFDQINKGDRVEIRFGTFTDYFNGLEKWYSDNEDHQPATLSGDFFPYMCALGDYWTGYYTTRPFFKRQGRLLHSLIRNSDIMLSMLRGNLKQRKIDENTKRLEDARRSLSLFQHHDAITGTSKVSVMDNYSEILHSSIGSMKIVLENLTKSDLDIYPRIHDGVEIQQVVDFSEDPTDKEIRIFNSLLFTITDVFSIRITLREVTVSIDGKSIEAQLEPLFQKGKAETDSFSLLFKATVPPLSMIKVRIQKGDSGGLTKIAKVESRDASAWELGQWVFFEIGNSESAFYSDWKVGSPTSSSLETPFLKVALNLSNGAIQTVVKQSDKSTFECQQSWHLYKEAGGGSYLMRLHTNPTEVKEFKWLKVAGPVRQSIYQKSKNVLQKTSINNVEGPSGEEIDISMSIDVTKERNTELMTRFTTNWAKPITFTDSVGMQLLRRDFYRLPIQSNYYPMPTSAVLQEGKQRISIVSNVEHGARFLENGSVEINIDRILNQDDGKGLGSGPDAIPSDMKPVDMKFKLVFDNLGKEDQPNIHYSTHTFRAQQAVQSVIYPPLLFDAKPKKEEDIEEIEENSNLRFPCDVQLLTVRPLSGDRQLMIFYRHATSCSSEKMSNCGADFKKSLMNLLIRLGVREAQKTDLSGVTAIGDKVNVENLPDVDIKTFDFLTLVLHR
The following text describes a protein:
Function:
Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.
Subcellular Localization:
Cytoplasm.
Sequence:
MKKAIVAGGGISGLATAYLLKTRAAEEGLELDVTLVEREERLGGKIWSIKEEGYLCEWGPNGFLDSKPQTLDLCRELGASDLLLRSNDNARKRFIYTGGALNRLPENGPMFLKSGLISWPGKLRLAMEPFIPKKAGDEDETLAAFGRRRLGDEALRKLIAPMVSGIFAGNPETMSLRSCFPRIAELEDEYGSLVRAMIRLAKKKKQEVAQGKAVASAAGPGGVLTSFRDGIQALTDILAERLGPDTIVSGQEVLEVSRGGSLPWRVRTGSIDMDADLVILATPAYATASIIQGVDSDMAGILRQIPYATMTVVCFGYDRERIAHDLNGFGYLIPKEEGMNTLGTLWDSSIFENRAPEGQVLLRSMMGGACFPEYVNLTDEEVTGRVKNDLATIMGITAPPSFVRIFRHHQAIPQYTVGHSTRVAALEQRAASLPGLFLTGNSYRGIGLNDCVAAANRTAGEAIAQLTSR
The following text describes a protein:
Function:
Participates in the control of the reentry into the cell cycle following pheromone treatment.
Miscellaneous:
MISCELLANEOUS: Present with 4010 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MAINQAHVHPHYTLPGVMHYLQTEFTKNERDRITWELERSEMKARIAELEGENRDLKHQLNQIQSKAVSPEGEKEEKHVPDSLLQSKLAVQENVKEIIYLLKGPNTVNQLESLNSREAGSELHDLEKLNVNTPKEEGSAKTNGMDILNNALLDTKPNPKQGPSESPSPTKVKSLFSTANKRENNETISKIHSELSKVDIISSYGDCMALYDADTKSLEIHQVDANLNSKLLKKISLGQDSDIMKFFWVSTSKLLVIEKSFHLKLFSISSASLISDVDLLQDSEQPFSSSDIINIDFKNKWLLIASKNKSQIRIWELDNIEAPEDVPINIKETYEITHDNDDDDSNDSTNILDCILGITEKSLILLSSNPYQLTIYDFEGKLLQKIDLKIDTILSGKPEEEGYHLFLDRKTSKLLIQLSNERLLVYSFDKKKVVLKEQLTPSSTLPIQLDLNDSIITVSYSNGDFEFRNLENLKPSIDEFVVADINFSERKEPVVFSSNLIVDSTPVLITVNKNNEVLLHKIKI
The following text describes a protein:
Function:
Has a role in cell separation where it is required for the degradation of the cell wall material surrounding the septum (the septum edging) which must be hydrolyzed before full separation of the daughter cells can occur. Hydrolyzes 1,3-alpha-glucan predominantly into pentasaccharides.
Subcellular Localization:
Secreted. Secreted, cell wall. Note=Associates with the cell wall.
Sequence:
MKLVLFLVLLFSALINLTNADKMVVAHFIVGNTYPYTVSNWEEDIQDAIAVGIDGFALNMGSDAWQVERIEDAYDAAASVSSDFKLFISFDMSIISADADFIEGVVRRFADKPNQLYYDGKVFVSTFAGETDTFGYSDVSTGWDSAVKEPLASAGYPIYFVPSWTSLGQGALEESVADGFLSWNAWPTTDADMNDNDDIGYQNLANSLGKLYVAPVSPWFYTHLSYKNWAYKSDWLIIDRWNEMLSVQPDMIEVLTWNDYGESHYIGNIQGALPAGSEGYVDGFDHTAWRYLMSPYISAYKLGLSEPYINFESLFYWYRPTPKSATATADSLSYPSGGDYMEDEIFVLVYLLQSAEVTVTCGSTTQTFSGVPGVNQFTIPMETNASPSFTVARQGGTLASGTGPEIVDSLSIYNFNAYTGVLYF
The following text describes a protein:
Function:
The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSNLDFCTIYTTTGQIDQLSYAQKAADSGDTCIGMKSKHGVVLLAEKPRVSPLYILESDEKIRKIGNTIGVVCTGMSSDTFYVGCAIKDYVFHHKENFNEDPTPGMMKVYLNDIFHYFTRGINLRVLGANTLTSVYKDGSFSLLHTDCSGKTLSYKAACIGKGTRRIKTELEKLDIDTMTIEEMVDVGVKVLYMAHDPSKDKEFDIEIGIASMETGGDLRKLENHEIRPLVGKYKHISVDED