lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Sequence:
MAAVAPPADQAADLLQKLSIDSQTKNIEVPEATKKPFTIQYGSVETAEAPNGPVQSCERSTTPLLQDFMDPSMCYLPNGYASTAYYYGGYDGHINEWDDYPRFVNPDGVEMSTGVYGDNGSLIYHHGYGYAPYGAYPPAGSPVPTMGHDGQLYGPQHYQYPSPYYQPPTPPPGGPYPSSQTSSQGELSTSVAADQAPLTVETTKEKANGVTNGNSNANNGSAPLKPTNQNSTLNLNNTYCRGVLSGGIPTSGYQDLRFGYDGMRSPVPWIDSPVFSDGQPKPATSSSFSSTVSHANNVHSGRNQNIRPLPHLVGLHHPRPASGMNPTPGFMNRMYPNNRDDVHKSIKYNVWASTPNGNKKLDAAYQEAQEKPDCCPVFLFFSVNTSGQFVGVAEMVGPVDFNKNVEYWQQDKWNGCFSVKWHIVKDVPNSLLKHITLENNENKPVTNSRDTQEVKMEQGLQMLKIFKEHSSKTCILDDFGFYETRQKTMQEKRAKQLQLQKQVWNGKPADIAVTDDKEKDGATGKPRLQKSLEVASVLLKESPTVHSNGEWKRSEENGTVTAVRDAPKGAKPVGTEKRVVANGVANGC
The following text describes a protein:
Function:
Probable subunit of a hydrogen-evolving hydrogenase that utilizes protons both as a substrate for hydrogen production and proton translocation. Acts by coupling the redox reaction via ferredoxin and iron-sulfur (Fe-S) clusters to proton translocation across the membrane, thereby conserving the redox energy in a proton gradient.
Subcellular Localization:
Cell membrane.
Sequence:
MTNNSERKRLEKRIAQLCKFIGRSPWVFHVNSGSCNGCDIEIIAALTPRYDAERFGVKLVGSPRHADILLVTGPVTNQSLERVKLVYEQTPDPKIVIAIGACPTGGSVFYESPFTNAPLDRIIPVDVFVPGCPPRPEAILHGVVLALEKLAKMIKGEVPPEEGEENE
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. Involved in the modulation of chloroplast development, growth and division in a cytokinin-dependent manner. Repressor of the gibberellic acid (GA) signaling pathway that regulates flowering and modulates greening, in a SOC1-dependent manner. Prevents the accumulation of SOC1 during flowering. Promotes chlorophyll biosynthesis throughout the plant, by regulating chlorophyll biosynthetic genes (e.g. HEMA1 and GUN4) and chloroplast localized glutamate synthase (e.g. GLU1). Involved in the regulation of sugar-sensing genes (e.g. HXK1, HXK2, STP13 and PLT6). Regulator of germination, senescence, elongation growth and flowering time. Influences also leaf starch content.
Subcellular Localization:
Nucleus.
Sequence:
MGSNFHYTIDLNEDQNHQPFFASLGSSLHHHLQQQQQQQQHFHHQASSNPSSLMSPSLSYFPFLINSRQDQVYVGYNNNTFHDVLDTHISQPLETKNFVSDGGSSSSDQMVPKKETRLKLTIKKKDNHQDQTDLPQSPIKDMTGTNSLKWISSKVRLMKKKKAIITTSDSSKQHTNNDQSSNLSNSERQNGYNNDCVIRICSDCNTTKTPLWRSGPRGPKSLCNACGIRQRKARRAAMATATATAVSGVSPPVMKKKMQNKNKISNGVYKILSPLPLKVNTCKRMITLEETALAEDLETQSNSTMLSSSDNIYFDDLALLLSKSSAYQQVFPQDEKEAAILLMALSHGMVHG
The following text describes a protein:
Function:
Probably binds to the DNA sequence 5'-TGAC-3'.
Subcellular Localization:
Nucleus.
Sequence:
EDNDLKNRLLNKYSGYLSSLWRELSRKKKKGKLPRDARQKLLHWWQLHYRWPYPSELEKAALAESTGLEAKQINNWFINQRKRHWKQA
The following text describes a protein:
Function:
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. It probably carries the active site for 3'-splice site cleavage.
Sequence:
MADGLMGTGTSATAGVVAPPALRRIWRGEEAVQQVVRGYLTRGNVLVWEPAEEKYLRAQWHLVPQPLGTLVNHVMQNGFHGPPYQLEPEAVTLLLAHGAIELYDGEAYQPPEPELIQHVREQRLDSVMLQMEHYCSTSELSTADPASEASLKPIASNEPGSDDATLVVADNETPTTTLDGEGSDDQDESIADMSVKDQAEPVPKRAKRAKRSKRADPDLPRTILPWRLNRADILRWLKMIEAMREQVKLPDLSRQELATSDPNTTWSSLKRSALKAVDSVRFMIPRLPTASRLESLPRAALAFPTTAQQRRREMVYHDLVQRGYYLTSGIKFGGDYLVYPGDPYRYHSHFVARVVPHTASISPMDVLALGRLGTVVKKAPVLCSVDVDRGTISYMSIEWTGAN
The following text describes a protein:
Function:
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MIQLMFIVILSEMALILAFLFRTPFRKLVILGLDQIKRGRGPIVVKTVAGTVLVALMTSVYSIIKIKNSRIDKAAIVSPTDQVLMVKHLLEATLMGCSLFLALMIDRLHHYIRELRIRRKSMEAIKKQNRGSEDGKASSLDEIKALENEIATSRTRLKQLESEIETKTKDVHTAESNVLALRKQSEGFLLEYDRLLEENQNLKNQLKSLDRKMSRSGSKKDS
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MLELWGVLSLTSLGVMVIFLFSKIKSSFAESVKYAGYMNAVLLSILLMSDESEMLFLKWEWVKLGGYSLMISFRFDLYTCCFFVVGLYVTWNILMFSFYYMSTDPRIDLFCKYLGLFLIAMLLLVSAESLFQLLIGWEGVGIMSYLLISWWYARSDANTAALQAIFYNRVGDIGLLIMLMWSLVTLGDWSFTGLYALDFVNTFFLLGVVLAAAGKSAQLGLHPWLPAAMEGPTPVSSLLHSSTMVVAGVFLLIRFSPIILNHKEIQLMVFFLGTMTTLFSAICALAQNDMKKVVAFSTASQLGLMVTVVAGAGAPQLAFLHICMHAFFKAMLFMCSGGFIHGLQNEQDVRKMGGLHSAAPITSVCFFIGSAALMGVPFLAGFFSKDPIIEIININNLNSWAVGLVLIATSFTAAYSVRLLYFSVGGVSRMLVLQPMNEEYGNLIGPLQRLAYSSVIAGVVFIYFLSPNQISCLSLPLSLKLAAVFVTLVGGLIAWDVVNLLHREESVTNIPELAFEAQVGFYPLIMHKLIPKVWLNMGEMYQMQVMDRGWTELALPQGLGGNYKIMADNVVNAQTSLIKMYIAVMVMMGGLILGIMICL
The following text describes a protein:
Function:
Acyltransferase required to remodel newly synthesized phospholipid cardiolipin (1',3'-bis-[1,2-diacyl-sn-glycero-3-phospho]-glycerol or CL), a key component of the mitochondrial inner membrane, with tissue specific acyl chains necessary for adequate mitochondrial function (By similarity). Its role in cellular physiology is to improve mitochondrial performance (By similarity). CL is critical for the coassembly of lipids and proteins in mitochondrial membranes, for instance, remodeling of the acyl groups of CL in the mitochondrial inner membrane affects the assembly and stability of respiratory chain complex IV and its supercomplex forms (By similarity). Catalyzes the transacylation between phospholipids and lysophospholipids, with the highest rate being between phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) and CL. Catalyzes both 1-acyl-sn-glycero-3-phosphocholine (lysophosphatidylcholine or LPC) reacylation and PC-CL transacylation, that means, it exchanges acyl groups between CL and PC by a combination of forward and reverse transacylations. Also catalyzes transacylations between other phospholipids such as phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) and CL, between PC and PE, and between PC and phosphatidate (1,2-diacyl-sn-glycero-3-phosphate or PA), although at lower rate. Not regiospecific, it transfers acyl groups into any of the sn-1 and sn-2 positions of the monolysocardiolipin (MLCL), which is an important prerequisite for uniformity and symmetry in CL acyl distribution. Cannot transacylate dilysocardiolipin (DLCL), thus, the role of MLCL is limited to that of an acyl acceptor. CoA-independent, it can reshuffle molecular species within a single phospholipid class. Redistributes fatty acids between MLCL, CL, and other lipids, which prolongs the half-life of CL. Its action is completely reversible, which allows for cyclic changes, such as fission and fusion or bending and flattening of the membrane. Hence, by contributing to the flexibility of the lipid composition, it plays an important role in the dynamics of mitochondria membranes. Essential for the final stage of spermatogenesis, spermatid individualization (By similarity). Required for the initiation of mitophagy (By similarity). Required to ensure progression of spermatocytes through meiosis (By similarity).
Miscellaneous:
MISCELLANEOUS: The enzyme was named after a masochistic character Tafazzi, once popular on Italian television, apparently due to the difficulty encountered for its identification and characterization.
Subcellular Localization:
Mitochondrion outer membrane; Peripheral membrane protein; Intermembrane side. Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The HXXXXD motif is essential for acyltransferase activity.
Sequence:
MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNKEVLYELIENRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine. In the first step, a glutamine amidotransferase generates ammonia that is channelled between the binding sites of glutamine and chorismate and used along with chorismate in the second step, catalyzed by aminodeoxychorismate synthase, to produce ADC. Required for the synthesis of 4-aminobenzoate (PABA), an important component in tetrahydrofolate biosynthesis. Does not possess ADC lyase activity.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAALCLTAPAIARWSPPPSPRRWQHPLCQDCARRRRGLARRRASGDDGPEEAEAPPVRTLLVDNYDSYTYNLFQELSVVNGVPPVVVRNDEWAWGDVYYWVYKKRAFDNIVISPGPGSPACPGDIGLCLRIVSECGDIPILGVCLGHQALGLVHGAKIVHAPEAIHGRLSEIEHNGSYLFNHIPSGINSGFKVVRYHSLVIEATSLPEDLVSIAWCASPKMLSFVDSDQADNCPLLGSLNNFSITHPSEVTNNREVPLTIHNPGKPDGYKIIMGIKHSSRPHYGVQFHPESIATRYGRHIFQNFKRITTEYGSPSSSFLERKAHSAGRKRSGHVLDRADVWPAAGGPDRTGPNHLRTARLGHLQH
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MARHTLSSWWTFSRIATKSFDDREYDAYRLCYRHQQPYLSKKQRETCYTRLDLMRAVIHGLKMSIKECKRLFKYRRWNCTTFANGPHVFGKMELSGHRESAFLQALTTASVVHTVHKRCYSGKIKNCNCGSGGNSDAIRKRFVTSSFKWSGCRDELAFGEKFARDFIDDENEVGPKSGLDLMRMRNNAAGRRAVRKSLRLNCTCYGASGSCTVRTCWNSTAEFSEIAEFLMSKYNSAKHVYIDTNNLISHYHTSLSRIKRNKKPKPFKLSMIDRKLKRPAKDDLVYVDFSPDYCQTNHELGRQEYKHI
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MSSLYYANALFSKYQVASSAFSTGVFPEQTSCAFSCSSQRASGYGSASTGAPVSSSSSVSLPSMYTNGTSLSSHTQGMYPTAYELGAVSLNMHSSLFDHPNLPMVSAGDLCKAQSSGKEEQRGYHQNNENNLRIYPWMRSTGADRKRGRQTYSRYQTLELEKEFHFNRYLSRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKSTDRCSPAADQIGGDEEEEDDE
The following text describes a protein:
Function:
Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments. Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1.
Subcellular Localization:
Cytoplasm.
Sequence:
MAPPTGNVVDSQSPRPPANQLRWDLSAEQIERMAAELTERTKLVYDRVGSQEQGEVSYENTLKALADVEVEYTVRRNMLDFPQHVSPCKDIRAASTEADKKLSEFDVEMSMRQDVYQRIVWLQEKAESASLKPEAKRYLERLIKLGKRNGLHLPEETQEKIKAIKKKLSVLCIDFNKNLNEDTTFLPFSREELGGLPEDFLNSLEKTEDGKLKVTLKYPHYFPLLKKCYVPETRRKVEEMFNSRCKEENCLILKELVDLRAQKASLLGFSTHADFVLEMNMAKSSKTVATFLDELAQKLKPLGEKERAVILDLKKKECEKRGLEFDNRINAWDMRYYMNQVEETKYSVDQNLLKEYFPMQVVTTGLLAIYQELLGLTFHLEEKAQVWHEDVQLYTVKDTSSGETIGKFYLDLYPREGKYGHAACFGLQPGCLLPDSSRQISVAAMVANFTKPTPDAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEKEPLLRMSRHYKTGSPIPDELLEKLIKSRQANTGLFNLRQIVLAKVDQALHTQTKADPVEVFAQLCEEVLGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGIMNCKVGRMSCVAKLRGCLPQGMEVVGGTAVRSAGCGCPARNSHLSPCRWAWIIGIVSCTLVGPWMLLTC
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Subcellular Localization:
Cytoplasm.
Sequence:
MYERSTEKGSVWVTMKRCECSFFFLCWFVRWFVDLGFLERSGFDADAFVLMCAASLKCAARLKKMEKKGQTVEYMCLVRATDGKRNISTSLAAKDYAKFQASYALVLKAHMHALKKRERKDRKKTVEAEKVPEKEPKKQKKSSSKKSSGSK
The following text describes a protein:
Function:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MPRSRGGGRSGQEAGRTELVSRSLQSAQHCLASRDFGTAYAHYLLVLSLAPELRDDVKETFQYTLLKWAEELYSLNRVQDLFGCYEHALELFPDDEVICNSIGEHLFRMGFRDEAAGYFHKAVKLNPDYTDAKENFYRVANWLVERWHFIMLNDTKRNMTYNSAIQKVVRLGCKTVLDIGAGTGILSMFAKNAGAHRVYACELSKTMYELACDVVAANKMETGIKLLHMKSLDIDVPKHIPERVSLVVTETVDAGLFGEGIVESLIHAWEHLLLQPKPKGKDGNCEEYGQVIPAGAVVFGMAVECSEIRRHHRLDVQDLAGVHLPANVKFQSLAYSSIDSEETIEPYTTEKMSRVPGGYLPLTESFESMAVDFNNLQELKNLATKKPHKMIIPVIQEGVLDAIVVWFVLQLDDEHSLSTSPHEETCWEQAIYPVQNLPDYFVKPGDHVTMEVSCQDCYLRIQNIHIINADHEMDVERSSNKNEEESHALGSEAELCSALAGLQTSKPDEIRQLCTLESTEIALLNNVPYHEGFKAAMNKVLTSLAPSKQSQIMDVEDGGGEMNSGNSQGGNSIHFTTDPFYVLDVSEGFSILPIIAGTLGLVKPYSSVEKEQHRLTLDLISEANHFPKDTLEFWLRHVEDDCAVLQRPKSDKLWSIIILDVIETSGLIQQEMMEKAAISRCLLQSGGKIFPQYVLMLGMLVESKTLIEENAVQGTEPTLGLNIAPFINQFQVPVRAFLDLSTLPCIPLSKPTELLRLDLMSPYLNDSNREVKVQICKSGQVTAIPFWYHVYLDEEISLDTSSETSHWKQAAVVMDNPISVEMGQELVLIVQHHKSNISITVKQ
The following text describes a protein:
Function:
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MYPPVDPVIIQLGPLTLRWYGVLIMAGVMLAAWVGSRHVERRGFDRESVWDLLLWVLIPGLLGARLYYVFIQSSRGPEGLERFLSNPASILAVWEGGLHIFGGFIFGALGLWAFARMRKVPILVYADAIALGLPLGQAVGRWANFINQELYGPPTTLPWGLRIDPEYRIGPYRDLVAFPETTRFHPLFLYESLWNLIGFALIFFIWRRYGDRLRDGDIALMYLVWYPLGRFFIEFLRTDSWFFPGTPFNVVHVLSFAAVVGASVLLYRRYRYPTVSAKAES
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MGGGDLEALGENLVQPEDLDNPSAEFTKGEPQPPQCRDAWAALLFYSQFIAIAVVGGVLGVPAVQRQMDNVDTNNNAYQSSGELDYSGLIYVTLIGAGSSFVLSAISLFVMAMCPKVLIQISLLFSLVVSIFACVVSFMYGSILGGVFGAIFFLISVCYACAVWRRIPFAAANLNTGLTAVKKNSGVVLFAYTITIVSFFYSMLWMTALVGVYDKEGVIDEAGNFTENNLTWAYFFLLLLALFWSEQVFQNTIHVIIAGVVSTWWFAPDEASSCCSKAIKDSFVRATTTSFGSICFGSLLVAIIQTLRSMVESARHNDDNGACGSIMLCLVDCCLSCVEGMLEYFNKYAYIYVGMYGYSYLEAGKNVMTLFQQKGWTVIINDDLISNVLSLFCFVVGCLTGCVGLVMNELNPSWFEGYSSEATGMSVAFGFPFLIGVVISAILFSVVDSSVNTVMVSFAEAPMEFEQNHPELSSEMRQAWRLVYPAECGF
The following text describes a protein:
Function:
Thought to form a complex that enhances transcription from repetitive DNA sequences by modulating chromatin structure.
Sequence:
MLTRGKIPNVSDGANCQDSEDKEDDDEETMNDDNSSEKDSSSSKDKQSECKVPFRPLSALQMKRTPSADRANMSPVLTGQRSSRSNSRRGQFVTDISSEDTPLSKRQVMKSGGGKRKRLVLVEPEETSQEAEEISQEAEAKLNSTEESHDEEVNSTNQRNISVAESETEKHDESHDGVRRSQRAKRQMYTYNDSWIFAEKNVKGYPAAIKEEDTAAEGNDRMHTRRRNLVPKRQEEVDQDIEDEEDARQIANRRAQIRKRNKAKKKKVSRYQTSMNDQDMYTEIKNRRLRSSSNSSRPNYSGYHSTVINAKKTPARSQRHRRPQYESSNEFHVTLRICNSTLESETKSESESQSEDEQESPKGKRREELSDHSRDQDNEETERTAPALGGERVKGKYTLRKIQPIERYCPENEESHNRSRSTRHTSRIVCSPAHRAQRKRRQKAQNESTTSSSSSSDEERFERRKNKSMSKARNRCLPMNFSPDDLGNGVVKDRMKIGSSLADVDPMKVDREVTFEQVGGLETYVRSLKEMVLFPLLYPEVFQKFTIQPPRGVLFYGPPGTGKTLVARCLANECSQKDRRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSTRQDQIHSSIVSTLLALMDGLDSRGEVIIIGATNRLDAIDPALRRPGRFDREFHFPLPSLPARKEILDIHLKSWTPAPAPSLVHYLSQKTVGYCGADLKSLCAEAALLALRRRYPQVYNSKDKLMLDLSQINVERRDFEQAVQRLVPASQRSAMASGKPLSSVVTPLLDSLFHELIQATQLLFPEGIATLKLKGPLSGVKKQTSNQIFPRLLVLGDCCSNITSALLHYMERLPVHRLDLSTLHGLAARSPEEACVQLFQEARRNVPAIIYLPLVSRWWSAIGETVRATFLTQLSELDPELPIFLLITNDTELDGLPDDLCDLFHEEDGEIFHTRPFTSEERQNFFRPLVVTKCLKPPMVRKTPKSKLEVLPLAPAPPPRQLNEKEKERLERKEEATLRELRIFLREILAKMARNKLFYMFTRPVDTKEVPDYLQVIKRPMDLETMMTKIDQHAYESAKDFLADIEQICANALEYNPDKSPEDKMIRHRACTLRDTAYALIKAEMDTDFEEQCQEISRTRKSRKDKVAPIAGPPALLDPASTAITSGNDSKGNGEATKSEIKVSKTRNRRGGGWSQGIIKSAAKKRKADSESLLNDSSMTAQDQSQENGIDDVVQQASASDEPPVLTAEDPTPDDSQASDAFDSQPEIDSGAAPLLIVSKKSVIINVDKLEALLDSIVAKTENWSLEKLLRLYSKLSKLIDRYLRLYDRQPLVEEMTQMLSNCR
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MTATRPDFEQEDNPPETDDALDSKDEFPDEVEMTLGEHLEELRTRLFWALGTFIAATIGCFIFVKPIVDLLQKPAGTTVKFIQTIPGEFFFVSFKVAAYSGLMVAAPMILYQIVRFVLPGLSRRERKLILPIVVGSSVLFVVGVVFAFMVLAPAALNFFVSYGDGVVDQTWTIERYFDLMFVMLISTGIVFQVPILQVLLGVTGIVSSERMFSVWRYVSVFAVVLGAVVTPSTDPLTQTFLAGAVTILYFGGAGAVKLIGK
The following text describes a protein:
Function:
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
Subcellular Localization:
Cytoplasm.
Domain:
The PRC barrel domain binds ribosomal protein uS19.
Sequence:
MMEEYVVIGKVLDTFGLEGELKVRPYAPPEVFENLEKVYLKRKGGDWVPFEVEWVDFIDDKVIIKFKGYDSIDEVEQFKGAKLFLPKEELPELGEEEYYAYELVGMEVETDKGKKLGKVERVQDMGPYDALVLDKENLLVPFVSDIVLKVDKENKKIIVKEELLPV
The following text describes a protein:
Function:
Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways. Directly binds the E box motif (5'-CANNTG-3') on promoters and promotes transcription of neuronal genes. The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro. Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Involved in the regulation of neuroendocrine cell development in the glandular stomach (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MESSAKMESGGAGQQPQPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQQQQQQAPQLRPAADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF
The following text describes a protein:
Function:
Participates in the catalytic exchange of histone H2A for the H2A variant HZT1, an euchromatin-specific factor, leading to chromatin remodeling and changes in transcription of targeted genes. Indirectly involved in vacuolar protein sorting.
Subcellular Localization:
Nucleus.
Sequence:
MKALVEEIDKKTYNPDIYFTSLDPQARRYTSKKINKQGTISTSRPVKRINYSLADLEARLYTSRSEGDGNSISRQDDRNSKNSHSFEERYTQQEILQSDRRFMELNTENFSDLPNVPTLLSDLTGVPRDRIESTTKPISQTSDGLSALMGGSSFVKEHSKYGHGWVLKPETLREIQLSYKSTKLPKPKRKNTNRIVALKKVLSSKRNLHSFLDSALLNLMDKNVIYHNVYNKRYFKVLPLITTCSICGGYDSISSCVNCGNKICSVSCFKLHNETRCRNR
The following text describes a protein:
Function:
Component of pre-mRNA cleavage complex II, which promotes transcription termination by RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MSEQTPAEAGTAGAREDACRDYQSSLEDLTFNSKPHINMLTILAEENLPFAKEIVSLIEAQTAKAPSSEKLPVMYLMDSIVKNVGREYLTAFTKNLVATFICVFEKVDENTRKSLFKLRSTWDEIFPLKKLYALDVRVNSLDPAWPIKPLPPNVNTSSIHVNPKFLNKSPEESSTPGTVVSSPSISTPPIVPDIQKNLTQEQLIRQQLLAKQKQLLELQQKKLELELEQAKAQLAVSLSVQQETSNLGPGSAPSKLHGSQIPPMAVKAPHQVPVQPEKSRPGPSVQIQDLKGTNRDPRLNRMSQHSSHGKDQSHRKEFVMSTLNQSDIKTSKTMPSEKLNSSKQEKSKSGEKITKKELDQLDSKSKSKSKSPSPLKNKLSHTKDLKNQESESSRVSDMSKRDPRLKKHLQDKTDSKDDDTKEKRKTAEKKDKDEHMKSSEHRLVGSRNKIINGIVQKQDTVMEESEKQGTKPGRSSTRKRSRSRSPKSRSPIIHSPKRRDRRSPKRRQRSMSPTSTPKAGKIRQSGVKQSHMEEFTPPSREDRNAKRSAKQDIRDPRRVKKTEEERPQETANQHSTKSGNEPKENVENWQSSKSTKRWKSGWEENKSLQQGDEHSKAPHLRHRESWSSTKGILSPRAPKQQHRLSVDANLQIPKELTLASKRELLQKTSERLASGEITQDEFLVVVHQIRQLFQYQEGVREEQRSPFNDRFPLKRPRYEDSDKPFVDSPASRFAGLDTNQRLTALAEDRPLYDGPSRPSVPRDGPAKMIFEGPNKLSPRIDGPPAPGSLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSAGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPSGGIRFEGPLLQQGVGMRFEGPHGQSPGMRFEGQHSQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQSGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESFNQTGPYNDPPGNAFNTPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQSFSNPLNRASGHYFDEKNLQNSQFGNFGSLPAPITVGNIQASQQVLTGVAQPVAFGQGQQFLPVHPQNPGAFVQNPSGALPKAYPDNHLSQVDVNELFSKLLKTGILKLSQPDSATTQVNEVAAQPAAEEEEDQNEDQDVPDLTNFTIEELKQRYDSVINRLYTGIQCYSCGMRFTTSQTDVYADHLDWHYRQNRTEKDVSRKVTHRRWYYSLTDWIEFEEIADLEERAKSQFFEKVHEEVVLKTQEAAKEKEFQSVPAGPAGAVESCEICQEQFEQYWDEEEEEWHLKNAIRVDGKIYHPSCYEDYQNTSSFDCTPSPSKTPVENPLNIMLNIVKNELQEPCESPKVKEERIDTPPACTEESIATPTEIKTENDTVESV
The following text describes a protein:
Function:
Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MEEEDITLEHSDDLNKEESGESNRVNIEEPEHHDNSNKESTNLDDLNMLEEPKYHDNSNKESTNLDDLNMLEEPEHHDNSKKESTNLDDSNMLEEPKHHDNSNKESTNLDDLNMSEEPKHHDSSNKESTNLDNSNMDESENQKNFKIEEPKPSGDFRNEGPKQCDDSKIEKPELHVNSKIEEPIHRIDSEHNEPEYHTESKNEESEHNTKSIREEPIHHVDSKNEEPVYSKIPEKMGDEFSENSLSKSDSAVKQEGNLLIHPNNSLKDTAPSKCKEPPVDEALSKKEISDDIAQITSVTPITEKIEDKDKYISEVIDTYGKLADGFEYRAKTFCLEGRGKVLYMLGTECSRLLGFKDSYFMFHKTPSLRKVLTTQSERDQMVEMGLLASNFRFRQLSIVPARQMFLAFGARILMKGTIDPESHKALIEKNISWADDEYYHMDVMANGSTRSSSVKLELKSMDNQNSPSPFQGKDILTLAQGASFYNSKVMRTRNLRKEARLSYYTKLRGVNRSVS