lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable serine/threonine-protein kinase that may be involved in ribosome biogenesis.
Miscellaneous:
MISCELLANEOUS: Present with 861 molecules/cell in log phase SD medium.
Sequence:
MVKETPLHSSSSTSLSSLFRPTKLKNLSAKIFNGGGNQSYSKTDDVSRSSSRSSKKNTDSDQEDQIKYNKPNDRRSTIGKSPQGNGALSKESHVVASSTLTGISPTSAKKAPIDYSPSRPLPNNHNPVRTGHTVPHLPHSIHNPINYIHQGSKDAFHHPHPVRSTAHSNISTVSSAKSDTPSSNLSYQAHMHPVEILQKQIEDKHFMDSQASTPGSVELQHNSSSGSDDTSSRKKKSLRLTRFFKKIHNDYHDNHHHHHHHNRGSTPTKPKLNLNTNENIVESNGKALYETDNPVELLEKYGIPGRKLGEGASGSVSVVERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYDFFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRFPWKAPKKSFNSFRLFTEEPEDEDDIVRGPNKILRLLPRHSRTIIGRMLALEPKQRVLMNDVVKDDWLVSVPSCEVDPTSGDLVEKPKNHKHHLVTEEELNELTKQHGNKDSN
The following text describes a protein:
Function:
Binds to phosphatidic acid and to phosphoinositides such as PtdIns3P, PtdIns(3,4)P(2), PtdIns(3,4,5)P(3) and PtdIns(4,5)P(2). Catalyzes guanine nucleotide exchange on specific Rab proteins.
Sequence:
MADLVTYSNADHNLEQALITLKKGTQLLKYGRKGKPKFYPFRLSSDEKSLIWISSSGEKRLKLASVSKIVPGQRTAVFQRYLRPEKDYLSFSLLYNGKKKSLDLICKDKVEAEIWIGGLKTLISTGQGGRSKIDGWSGGGLSVDASRELTSSSPSSSSASASRGHSSPGTPFNIDPITSPKSAEPEVPPTDSEKSHVALDNKNMQTKVSGSDGFRVSVSSAQSSSSHGSAADDSDALGDVYIWGEVICDNVVKVGIDKNASYLTTRTDVLVPKPLESNIVLDVHQIACGVRHAAFVTRQGEIFTWGEESGGRLGHGIGKDVFHPRLVESLTATSSVDFVACGEFHTCAVTLAGELYTWGDGTHNVGLLGHGSDISHWIPKRIAGSLEGLHVASVSCGPWHTALITSYGRLFTFGDGTFGVLGHGDKETVQYPREVESLSGLRTIAVSCGVWHTAAVVEIIVTQSNSSSVSSGKLFTWGDGDKNRLGHGDKDPRLKPTCVPALIDYNFHKIACGHSLTVGLTTSGQVFTMGSTVYGQLGNLQTDGKLPCLVEDKLASEFVEEISCGAYHVAALTSRNEVYTWGKGANGRLGHGDLEDRKVPTIVEALKDRHVKYIACGSNYTAAICLHKWVSGAEQSQCSTCRLAFGFTRKRHNCYNCGLVHCHSCSSKKAFRAALAPSAGRLYRVCDSCYVKLSKVSEINDTNRRNSAVPRLSGENRDRLDKSEIRLAKFGTSNMDLIKQLDSKAAKQGKKTDTFSLGRNSQLPSLLQLKDAVQSNIGDMRRATPKLAQAPSGISSRSVSPFSRRSSPPRSATPMPSTSGLYFPVGIADNMKKTNEILNQEIVKLRTQVDSLTQKCEFQEVELQNSVKKTQEALALAEEESAKSRAAKEAIKSLIAQLKDVAEKLPPGESVKLACLQNGLDQNGFHFPEENGFHPSRSESMTSSISSVAPFDFAFANASWSNLQSPKQTPRASERNSNAYPADPRLSSSGSVISERIEPFQFQNNSDNGSSQTGVNNTNQVEAEWIEQYEPGVYITLVALHDGTRDLRRVRFSRRRFGEHQAETWWSENREKVYEKYNVRVSEKSTASQTHRDRDEEEEDIPH
The following text describes a protein:
Function:
May participate in the pathogenesis of meningococcal disease.
Subcellular Localization:
Cell outer membrane; Peripheral membrane protein. Secreted.
Domain:
The Gly-rich region is probably involved in binding calcium, which is required for target cell-binding or cytolytic activity.
Sequence:
MNEGEVVLTPEQIQTLRGYASRGDTYGGWRYLANLGDRYADNAAAIVGKDTNLNGLNLWMKKGVENLWDDTVGKKTRLEKFDRVALQHFSQYVDLINKNNGRLPNTSEIERSYYKAVTYHGVSSSAAIDLVINRSLPDMADGYWALGLGIEAERIHNEQAVNNPNGSERDNRKQLISALDKGFDGSFKEKHFTFLQSVMMDLTKLGVEYTIDGWQKIGGWGNGIINDLYKSVVKREWTGIFEIVNNNIKQGNEAFKNEINSLVHDMKAAGKEFGDDLNTQWNNLTQAAEIIYNDIVDNTSQGIEKGVKAIKELSEKMKNAASDLADGSAEKAKQVVEDLAQAAKEAYENAKSTAEKAAQAAREFFKGLPSFKDLAEKFRDLFPNPEGWIDDGHQCFAPWVKETKKRNGKYHVYDPLALDLDGDGIETVATKGFSGSLFDHNRDGIRTATGWVAADDGLLVRDLNGNGIIDNGAELFGDNTKLADGSFAKHGYAALAELDSNGDNIINAADAAFQTLRVWQDLNQDGISQANELRTLEELGIQSLDLAYKDVNKNLGNGNTLAQQGSYTKTDGTTAKMGDLLLAADNLHSRFKDKVELTAEQAKAANLAGIGRLRDLREAAALSGDLANMLKAYSAAETKEAQLALLDNLIHKWAETDSNWGKKSPMRLSTDWTQTANEGIALTPSQVAQLKKNALVSLSDKAKAAIDAARDRIAVLDAYTGQDSSTLYYMSEEDALNIVKVTNDTYDHLAKNIYQNLLFQTRLQPYLNQISFKMENDTFTLDFSGLVQAFNHVKETNPQKAFVDLAEMLAYGELRSWYEGRRLMADYVEEAKKAGKFEDYQKVLGQETVALLAKTSGTQADDILQNVGFGHNKNVSLYGNDGNDTLIGGAGNDYLEGGSGSDTYVFGKGFGQDTVYNYDYATGRKDIIRFTDGITADMLTFTREGNHLLIKAKDDSGQVTVQSYFQNDGSGAYRIDEIHFDNGKVLDVATVKELVQQSTDGSDRLYAYQSGNTLNGGLGDDYLYGADGDDLLNGDAGNDSIYSGNGNDTLNGGEGNDALYGYNGNDALNGGEGNDHLNGEDGNDTLIGGAGNDYLEGGSGSDTYVFGKGFGQDTVYNYDYATGRKDIIRFTDGITADMLTFTREGNHLLIKAKDGSGQVTVQSYFQNDGSGAYRIDEIHFDNGKVLDVATVKELVQQSTDGSDRLYAYQSGNTLNGGLGDDYLYGADGDDLLNGDAGNDSIYSGNGNDTLDGGEGNDALYGYNGNDALNGGEGNDHLNGEDGNDTLIGGAGNDYLEGGSGSDTYVFGKGFGQDTVYNYDYATGRKDIIRFTDGITADMLTFTREGNHLLIKAKDDSGQVTVQSYFQNDGSGAYRIDEIHFDNGKVLDVATVKELVQQSTDGSDRLYAYQSGSTLNGGLGDDYLYGADGDDLLNGDAGNDSIYSGNGNDTLDGGEGNDALYGYNGNDALNGGEGNDHLNGEDGNDTLIGGAGNDYLEGGSGSDTYVFGKGFGQDTVYNYDYATGRKDIIRFTDGITADMLTFTREGNHLLIKAKDGSGQVTVQSYFQNDGSGAYRIDEIHFDNGKVLDVATVKKLVQQSTDGSDRLYAYQSGNTLNGGLGDDYLYGADGDDLLNGDAGNDSIYSGNGNDTLNGGEGNDALYGYNGNDVLNGGEGNDHLNGEDGNDTLIGGAGNDYLEGGSGSDTYVFGKGFGQDTVYNYHVDKNSDTMHFKGFKAADVHFIRSGSDLVLSASEQDNVRISGFFYGENHRVDTFVFDDAAISNPDFAKYINAGNNLVQSMSVFGSNTAATGGNVDANTQSVQQPLLVTPSA
The following text describes a protein:
Function:
Divalent cation:proton antiporter that exchanges calcium or manganese ions for protons across the Golgi membrane. Mediates the reversible transport of calcium or manganese to the Golgi lumen driven by the proton gradient and possibly the membrane potential generated by V-ATPase. Provides calcium or manganese cofactors to resident Golgi enzymes and contributes to the maintenance of an acidic luminal Golgi pH required for proper functioning of the secretory pathway. The transport stoichiometry remains to be elucidated.
Miscellaneous:
MISCELLANEOUS: Present with 2170 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Note=Colocalizes with Gos1p in the medial-Golgi stacks.
Sequence:
MGNMIKKASLIALLPLFTAAAAAATDAETSMESGSSSHLKSFLMSVSMIGLSEIGDKTFLIAALMAMRHKRVLVFSAAATSLAIMTILSGVVGHSAVAFLSERYTAFFAGILFLVFGYKLTMEGLEMSKDAGVEEEMAEVEEEIAIKDMNQDMDDVEKGGDTAYDKQLKNASIGKKIVHRIRELASFMFSPVWVQIFLMVFLGELGDRSQISIIAMATDSDYWYVIAGAVIGHAICSGLAVVGGKLLATRISIRTITLASSLLFFIFALMYIYQAFTTQD
The following text describes a protein:
Function:
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
Subcellular Localization:
Cytoplasm.
Sequence:
MTKFHVKLYSKAVESRKVSQIQRDFEKKFHRKLDVSVEYCYHLIVDEPDFIDTNWSKLSNLLSHSPFEKYVWRESILNSKNGKVIEICPRTAVKTATCTNILNVFDSADIRNVEKIERGIRYLVPNDVDENDFFELAADKMTEVIYSTDMNFDNESHSIENVTIIDVLASKQNLIEANEKLGLALDQDDLDFYYDFFVIKVKKNPTDVELFDLAQSDSEHSRHWFFRGEIWIDACEREQSLMGSIRDTLKYSNENSLIAFNDNSSSIRGFERVWRLRPSDPTTVSSMNAICSSSHLIYSAETHNFPTAVCPFQGATTGTGGRIRDVHATGRGAYEIAGTVGYSFGNLNIAGLDLPWEDPSFVYPTSISEPAKIAIEASNGASDYGNKFGEPVICGFARSFGLKLENGERCEYLKPIMFSGGIGTIDEDEVKKEPCAVGQKVVKIGGPVYRIGVGGGAASSVSVQGNRENQLDFAAVQRGDAEMGGKLHRVVRACAERNGGNPLTSIHDQGAGGNGNVIKELVEGCGVTVQSDAFQLGDESISLRELWTAEYQENDAALVNPSLLEALQTISEREKCHVSVVGDVMEEQRVKLVGKSGEIAVDLDTRQLGEREKKCFKLKSVPRILKKLELPKNLTVREAVGRVLKLPTVASKRYLTCKVDRSVTGLVAQQQCVGPLHTPLADVAVVALSHFDTVGGAVSLGEQPIKMLIDAEKGARMCISETIMNLIWAPITDLKVSKTRYSKKKLFLLKDVKMSGNWMWAAKCEGEGARLVEAVGGLCQGLREIGCAIDGGKDSLSMAVTANGEVVKSPGTLVLSAYAPCTNVSKVVNPSLKATPGSKILWIKCGGVKGKFRLGGSALAQVYSQIGDDCPDIENFSEISHVFSIVQDLLNEDQLVGTVRKPKILAGHDISDGGLITTILEMAFAGNVSIDIDIQKETDPINILFSEECGIVLEVSDAENVMKRCQSSVIECSVIGHATPEYGSDAHVKIQVNGKMEINEKLVDLREEWELVGDKLGEHQTNLKSLEEAKNVRKDCKKIQYKCDFEWFYHPSFIYHEQYFSTAPRVAIIREEGSNGDREMASAFTLAGFQTFDVTMSDMLKGHNLNSYRGVAFVGGFSYADVLGSAKGWAAGIQFNEKVSQSFKVFRSRSDTFSYGVCNGCQLMAQLGWVGDEDDESESVTVFLDENECGRFESNFGPVKIEQSRCIMLSGMENSILGLWSSHGEGQFNYRSSQNLENLRRNGQVCVRFCDDLGMTGADYSKEKLPYPWNPNGSIDDVAAICSRDGRHLAMMPHADRSFLTWQWADPDDVNWNTRFDQQSVALSPWIRMFRNAYNWC
The following text describes a protein:
Function:
Polyglutamylase which preferentially modifies alpha-tubulin (By similarity). Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity). Together with ttll-4 and ttll-11, required for male mating. Probably by regulating microtubule stability via the glutamylation of tubulin, negatively regulates axon regrowth after injury in PLM neurons.
Sequence:
MKPKNVPREIFNPFTNKTSLGTRREGLFLCKRLKLRPDNYLEEYCADLEVIDIMAPIRPADETERCPPTSTSDDQEAGDYLVSRNKKSRNSDYMLFSSDALVHIAHDAKVSEKYTWLGERLRLTFKMMRSDSRLIRTMCHSHGFMQCSSKNPSVNVIWMGAPVKSVRMRELMPWQRLNQFPRSTELTKKDRLYENIERSKSIFGESFDFIPEFYVTPRENRKMENAFVRVAKEIAAAGGELCFPGEFIVKPTNSRQGKGIFFANSMADIPAEGPLLVSRYLKDPYLVNNHKFDLRIYVAVTSFYPLVAYVYSEGLARLASRPYDTSASSADSNEYVHLTNYSINKNSTSFVRNESMSSEDLGHKWTLGALLRYVENEGKDAKLLMLRIEDLIVKSLLSIQNSVATASRTNLRFACTNFELFGFDVLVDQALKPWLLEVNLSPSLACDAPLDSLLKTRLIADLLNLACVPLLDRKIIDSVTPALRKSMNSQESESSETDDLELDPMCAKTLKRRPVGLKRSVLNKKIVSGSTSLIPNNEKKFDQIVRKAELEDGRRGDFIRVFPRNGTWGMYSPVMEDLGNEDFDERLFDEVVTKKNTKNSSGSSKASSSSASASSSSSSMHIEDLSDLFHEVMMQCDKYSSIADVPIEIREIISPWYEEASEYTKKITQEGETYACKLPVIRSTARLRTKSCAEFYEVRKVQLAKKKESEAMASKENEPIVLQAVVAKRI
The following text describes a protein:
Function:
Enhances production and/or transport of FGF19 and thus has a role in regulation of bile acid synthesis.
Subcellular Localization:
Cytoplasmic vesicle membrane; Single-pass type I membrane protein.
Sequence:
MLFFLDRMLAFPMNETFCCLWIACVFNSTLAQQGTESFQCDNGVSLPPDSICDFTDQCGDSSDERHCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVDSISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAERELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRVRLYNNKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFIALDHLWVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPVLTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIAEAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRPPKDHTLGNENGHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQILIKTEKGLSKVWQESKQNPGNHWQKADILLGKLRNFEVIFQGIRTRDLGGGAAIDDIEFKNCTTVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCSECPLNYCRNGGTCVVEKNGPMCRCRQGWKGNRCHIKFNPPATDFTYAQNNTWTLLGIGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTESSVYSFSNPLYGTTSGSLETLSHHLK
The following text describes a protein:
Function:
Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to coq7, therefore facilitating the coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Subcellular Localization:
Mitochondrion.
Sequence:
MISNILKKSNSLFLRSTLSSNKFTNVTILRNSLFLNNNNNDNNTNIKQTYNKINFFSTTVPNQNEKIELKQEQIKQEQQQQPEQQPEQQTNKINNEIELKIKILENSLKYVNSYGWTSEAVSKACIEMGYPPITQGILGEDSAYELALYFVTKCNTDLMIKLSDAENSEQQLLSGLSKKEKVKLALKLRLSMIKPFIGRWSEAMQLLANPKNIVNSSPSMLTLVDNIWYLVGDKSSDFDWYAKRGLLIALYTSAELFMLSDTSVDHSNTWRFVDDRVDDLIKTIKFKNDIEETVGITLNTFLQKIKK
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MYRKILTFKEAEEGSYLAEWSNLKCLVVDETDRMVEEGYFSELTDILNKIHEAADKEKLQTLVFSATLTFAKAQDVAEEEKKKAKELSAHQKIQRLIKLTGLRENKHKVIDLTRQMGTAGCLVEARINCGNLVEKDTALVYLLNRYPGRTMVFVNSVDAARRLHHILNAINIDPMILHAKMIQKQRLRNLEKFAESKNAVLIATDVAARGLDIQGIDHVIHYQVPKKVEIYIHRSGRTARASHRGLTVVLVDPQSRQFYMKLCKGLNRMQDLDIFPIDFEPLMIAIKKRVRLASEIDSLEFRCKKIKMSESWFEKAAREADLDYDETRSREMGGLNLEVDEMIRKSRQLQSQLRSELSAPLPRSDGSDSMRTKYITAEIVSRLRAVGDNAIDVLNQKIEDTKEWKRKNRKATKTDEMNSMKKSLKNSQKNKDRLAEKQRQAKMVKFSMANSLDDNK
The following text describes a protein:
Function:
Involved in the export of mRNA from the nucleus to the cytoplasm.
Subcellular Localization:
Nucleus.
Sequence:
MKGKGSRARSGASDRGGIRKRGSTRIDRDGDLSMDGDAARARGKRTRGDAGRATPAGGRPQARDRTLNAIQKAIASNADSQANIRQGTRGAGLEQVSVRGWKQSKAASNRDGGLESLIAFLEKKLTASDSKAGARARITKQKRAAVVLSGLSSSSPGMVFQNDDRQRLGSFFLLSSRVEGDSVIVSIRPGLLDRMLQMNGFSFAGAPLTIEAYGPSANGMTDQPMLSDIAQNGGAPSTADTKSKMTAILSKRYYQQTKLLDLSKLGSDPDLLAMGIFNSTSTESKFFPALMKVWEMSFDNSTTRREAVESVSLADNQLANIAVVTSLAQTIPDLRNLDLSNNNFKDAQSLIGWRWKFRNLEFLDLTGTPFSADPTFKETMMKWYPKLRVLNNVEVRTAEEIAAQKKTPIPVQPPHFFDESQIAENFVRAFFVGYDNDRNDLLNGVYDNHSTFSLNVNTSAPRAQQTETAGWDPYIKKSRNLLKINHLPARMSRAYVGVEKIREVWNSLPKTKHPDVAAHPNEWLIECFPVPGLPDLSGQSSTGVGGLLIMVHGKFEELIDGKVEVRSFDRTFILGPGGGVGGIRVISDVLCLRAYGGHEAWIPETPTVPPSVQTTIHPAAPQAVPEGYGMPLPGKPETQVQQEQLVMQMSTKTNMTLQYSEMALSGNGWNMDAALKNFEELKAQGTLPPEAFLPGTV
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDSVAFEDVAVNFTQEEWALLDPSQKNLYREVMQETLRNLTSIGKKWNNQYIEDEHQNPRRNLRRLIGERLSESKESHQHGEVLTQVPDDTLKKKTPGVQSYESSVCGEIGIGLSSLNRHLRAFSYSSSLAIHGRTHTGEKPYECKECGKAFRFPSSVRRHERIHSAKKPYECKQCGKAFSFPSSVRRHERIHSAKKPYECKQCGKALSYLVSFQTHMRMHTGERPHKCNICGKAFFSPSSLKRHEKSHTGEKRYKCKQCDKAFNCPSSFQYHERTHSGEKPYECTQCRKAFRSVKYLRVHERKHTGEKPYECKLCGKGFISSTSFRYHEKTHTGEKPYECKKCEKAFSFVKDLRIHERTHTGEKPFECKQCGKTFTSSNSFHYHERTHTGEKPYECKQCGKAFRSASVLQKHIRTHTGEKPYGCKQCGKVFRVASQLKMHERTHTGEKPYECKQCGKAFISSNSIRYHKRTHTGEKPYKCKQCGKAFISSNSFLYHERIHTGEKPYECKQCGKAFRSVSILQKHVRTHAG
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MPPPPSQKPGQASISAFFKPKSSQRPITKSCQPDRAQVSNGYARTSNLLDTDTGASSSAQPPHKRSKLNNKDGPRRETIDRMSKWKFTALQPSDNVSSELDEAASQATPTERSQHDQARHDAFRKTLLGPNFAIDRHASNQMQIDDMSSAHTFSHSESRTSTGTKVDAMVVDDDDDDDDNQHEQAAQSVPGTWNRFTGLAAPESTPAPCSHRDSSMNKTKGKPKASGAGTGPSYTPLEKQILELKAEHPGVLLIIEVGYKLKFYGEDARIASKELSIMCFPERNLLTAMIPVHRLHIHVKRLIQAGHKVGVVRQIETRALKAASKNAYTPFVRKLTALYTASTWVDDLSSLDDLAANMGDAYTNQPKSLMAIVEQSERGNAQADRVSIGIVSVEVNTGHLTYDQFSDGHARSELETRIAHLAPAEVLIPPQLTKPTEKVISYLLGNGADGGVRIERLAAMPDYNQAFQSVTRFYRDRGLESPEVPEVPEVPGSSEADTTRLATTLADGADKRSSPLISLIVSLPQLSLIALAQIIQHLQAFQLESICTLSTNFRSFSSRTTMLLNSNTLANLEIFRTANEQTERGSLIWLLDKCKSAMGRRLLRKWVSRPLTDIDKLQERLDAVEALRDGKSYVLRRLDSVLHGLPDLERGLARMTYGRATPTELATVLLSLNRVTQEFKADEAATWKTQSSLIDTHLLSLASGKQVVQTYLNQISIKEARANNKADLYLDADVFPAIQASKDNMAIIDGELREHLREIRKLLHRPSLDYVSVAGVDYLVEVRVADAKKVPVEWLRVSATKSMVRFHTPEVMRLSKIRDQHKETLDAAAQEAFARFVRELCKSEYVVLRNVVASLAVLDVLLSLAHVARAAGYTRPVFLRQPQDAEASVPVEIIGMRHAILEVVSAMPYIPNDVSLSTGDSGAAILLSGCNMGGKSSVVRALGLVIIMAQIGSFVAADVARIGVHDAVYVRMGARDRMFSGRSTYMVEVSETADILGSLTSRSMVILDELGRGTSSRDGYCLAAGVLEYLLTLGCPPNTVFITHYLQLASMQRRYPHLRNMHMAFTSNSRNLLDPIHLVYKLRPGIAHSFGIHAAHLARLPLQIIHSASTISSALYAKHTNRSAFLVLKHAFANPPQLATVSTLQHLLFTHPPT
The following text describes a protein:
Function:
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Subcellular Localization:
Cytoplasm.
Sequence:
MKDDHQNKQHQSNAQGSEEAFSHKTSGKNESEDTLTNRQGHPVTDNQNVRTVGNRGPTTLENYDFLEKISHFDRERIPERVVHARGAGAHGYFEAYGSFGDEPISTYTRAKLFQEKGKKTPAFVRFSTVNHGKHSPETLRDPRGFAVKLYTEDGNWDLVGNNLKIFFIRDPLKFPDLVHAFQPDPVTNIQDGERIFDFISQSPEATHMITFLFSPWGIPANYRQMQGSGVHAYKWVNEEGKAVLVKYHFEPKQGIRNLTQKEAEEIQGKNFNHATQDLYDAIENGDYPEWEVYAQIMSDDEHPELDFDPLDPTKLWYKDDFPWKPIGKLVLNKNPENYHAEVEQASFGTGVLVDGLDFSDDKLLQGRTFAYSDTQRYRVGANYLQLPINSPKKHVATNQEGGQMQYRVDRAEGQNPHVNYEPSIMGGLKEAKQDGKDHTPHVEGDVKREAIDRTNNFGQAGETYRRFTEFERNELITNLVNTLSTCRKEIQDQMIENFTKADPDYGKRVAEGLKKVSENNSNGPIGTTETEQAAKQAEQESHPSDPY
The following text describes a protein:
Function:
Seems to be involved in non-photochemical quenching, a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Extreme lateral location to the appressed thylakoid regions.
Sequence:
MAQAMLLMMPGVSTTNTIDLKRNALLKLQIQKIKPKSSTSNLFFSPLPSSSSSSSTVFKTLALFKSKAKAPKKVEKPKLKVEDGLFGTSGGIGFTKENELFVGRVAMIGFAASLLGEGITGKGILSQLNLETGIPIYEAEPLLLFFILFTLLGAIGALGDRGRFVDEPTTGLEKAVIPPGKDVRSALGLKTKGPLFGFTKSNELFVGRLAQLGFAFSLIGEIITGKGALAQLNIETGVPINEIEPLVLLNVVFFFIAAINPGTGKFITDDEEED
The following text describes a protein:
Function:
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
Sequence:
MAYVINEACISCGACEPECPVNAISSGDDRYVIDADTCIDCGACAGVCPVDAPVQA
The following text describes a protein:
Function:
Possesses 5'->3' exoribonuclease activity (By similarity). Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II (By similarity). Essential for vegetative cell growth and chromosome segregation (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MGVPGLYRHLSQKCPKIVSDVIEDETTIVDGEEIPGSDYSAPNPNGELDNLYLDMNGIVHPCTHPEGEEAPPSEDEMLLAVFKYTERVLNVCRPRKVLMMAIDGVAPRAKMNQQRARRFRSAKDAAIEAESTLESELKAKTIELQSSGEKGKSLETILDEFKQGLVNKPGKWDSNAITPGTPFMEKLAAALRYWVGYKLNTEPGWRDLKVVISDATVPGEGEHKIMEFIRSQRGDPTYNANTSHCIYGLDADLIFLGLATHEPKFKLLREDVFRQNKTAGHQKKPFIWLNIDILREYLREDLRFTHPQTKIPFDLERAIDDWVFLCFFVGNDFLPHLPACDVRDGSINVLVNQWKNGMTRWKDYITCDGHVNLAQAQDLLKNFATQEQRILVHQEQDRVEYEKSQANKAAKQQAHRDSKKLRQQGEQAALESMPLYDTKGESVGDVQLTNRELVGQRNDITLANLANQDAADKLRFMLKRGSDTGAEEPAKRAKIEEEPKEAESNSSEATPPTANPSIANDADLSNPNVTVHETTGYADHVQFHKSGYTERYYMNKFHAKEDEVDNLRRQVAEEYMKGVCWVLMYYYHGCQSWSWFYPYHYAPLAGDFDQISNMKVEFGESAPFRPYEQLMSVLPAASGHNLPAVFRPLMSEENSPIIDYYPENFQLDLNGKKQEWKAVVLLPFINADHLLEHVQAKYTELTPEEKDRNTLREEIVIFHRLGKYAKTLEKRGLMEKGVIVSKKPLVLNSHETSGLAGTVERQNEADRTSSKPHLTFPLNVSTDQTMPSFEADKNMAMTLEYKIPKLEYENKSMLLQGYIPPKYTLSDEEREAIRNRERQRRGGQQDSRLFSNTDHRQQQELLMNGSYLAFKKLSLRDQPPPAKEDWMLNDPKLAGDRGNGGYNNRGGFNNHRGGRGGFNNRGRGGFNHGGGGFNNSRGGYGGGGGGYGGGGGQGYGGGQGYGGGQGYGGGQGYGGGGYGGGQGYGGGGYGGGYGGGHRGGHRGGRGGHRY
The following text describes a protein:
Function:
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves CHL1.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite. Cell surface. Cytoplasmic vesicle membrane. Early endosome. Endoplasmic reticulum. Golgi apparatus, trans-Golgi network. Late endosome. Lysosome. Membrane raft. Recycling endosome.
Sequence:
MPGPTMAQALPWLLLWMGSGVLPAHSPQPGIRLPLRSGLGGAPLGLRLPRETDEEPEESSRKGNFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRHQHDDFADDISLLK
The following text describes a protein:
Function:
Participates in both transcription termination and antitermination.
Subcellular Localization:
Cytoplasm.
Sequence:
MSMIHLPGVNQQIETISRQRNLPKHAVKEALIEALKKGYERFRKTYRDPRENSEEMAFDNFIVELDTDREGFRVLATKTIVETVSDTDQEIALIEVREVAPDAEPGGTVVVDVTPEKGDFGRMAAIQTKQVLSQKLRDQQRKLIQEEFRELEGTVLQARVMRFEGRSVICAVSSGFGQNEVEAELPKNEQLPNEPYRIGSAFKVFLRKVWEGSRRGPQLLVSRADAGLVVYLFANEVPEIEDEIVRIVAVAREANPPSRTVGPRTKIAVDTLERDVDPVGACIGARGSRIQAVVNELRGEKIDVIRWSPDPATYISNALSPARVIQVRLVDPDARQAHVIVPDDQLSLAIGKEGQNVRLAARLTGWKIDIKKSSEYSAEAAYS
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MATLLKNTLKVLIGAGAVYVTLDKGAWEVSSEHGSKFLQEVKKNILPETVEYIEKAPSVKTINHAALNKWNKGVQTVFSFIGSVPETTQECFEKLKDQFK
The following text describes a protein:
Function:
Down-regulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Cell junction, tight junction. Nucleus, nucleolus. Cytoplasm, perinuclear region. Note=In epithelial cells, recruited to tight junctions (TJ) during the maturation of the TJ complexes. A nucleolar staining may be due to nuclear targeting of an isoform lacking the transmembrane domain. TNF-alpha causes translocation from the cytoplasm to the nucleus (By similarity).
Sequence:
MAARSWQDELAQQAEEGSARLRELLSVGLGFLRTELGLDLGLEPKRYPSWVILVGTGALGLLLLFLLGYGWAAACAGARKKRRSPPRKREEVTPPTPAPEDPAQLKNLRSEEQKKKNRKKLPEKPKPNGRTVEIPEDEVVRTPRSITAKQPPETDKKNEKSKKNKKKSKSDAKAVQNSSRHDGKEVDEGAWETKISHREKRQQRKRDKVLTDSGSLDSTIPGIENTITVTTEQLTTASFPVGSKKNKGDSHLNVQVSNFKSGKGDSTLQVSSGLNENITVNGGGWSEKSVKLSSQLSAGEEKWNSVPPASAGKRKTEQSAWTQDPGDTNANGKDWGRNWSDRSIFSGIGSTAEPVSQSTTSDYQWDGSRNQPHIDDEWSGLNGLSSADPSSDWNAPAEEWGNWVDEDRASLLKSQEPISNDQKDSDDDKEKGEGALPTGKSKKKKKKKKKQGEDNSITQDTEDLEKDTREELPVNTSKARPKQEKACSLKTMSTSDPVEVLIKNSQPIKTLPPAISAEPSVTLSKGDSDKSSSQVPPMLQDTDKPKSNAKQNSVPPSQTKSETNWESPKQIKKKKKARRET
The following text describes a protein:
Function:
Transcription factor that regulates synaptic specificity.
Subcellular Localization:
Nucleus.
Sequence:
MVLETSEGDTKKFLTNNNNSSASRNNNSHNNNNNNHSPKEIPEETGRSSSTSSNSIPNAHRTNAGQHLLGGSPSSACSTSVSGCGMPSEGLHPTAALQLYAAAAQLAPNGVRVPPWGPFLQFGVPGVFGPNGPFLGRPRFDAASAGGHPNSAAAAAAATQMAAVNASNAFANLTGLSAAALRNVSAAQTTAVAAVASTVATIQHRLMIGNRQSLPPAGPPSEGSNEDGGFPGDGDDDSSAAKRRRSRTNFNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRKREHTKKGPGRPAHNAQPQTCSGEPIPPNELKAKERARRRKKLAKAIDRQARKLQAKGITVDLEALKAEYISQHKANGTFSDSDLEDDGIQIDVVGGTDSDDEGDSDAVSPVRLGGGGGGGGGTGGGGGGGASSSLHCGLDGDGDSSRAGSFIGGGGSLGSPSSVAPPSMLSNGAVQFGKLEPMDGNESEERDRERDSPKPLLFPAKAFHQLNLQSSQQHHGLVVGQGQGSGSGHGHGHQHNHHQHHLHHGSASASAAAAVANLVHQTSPISMRRSNPFSIESLLFNNT