lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the epidermal cornified cell envelopes.
Subcellular Localization:
Cytoplasmic granule. Note=Found in keratohyalin granules in the granular cells of the epidermis.
Sequence:
MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQSLDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ
The following text describes a protein:
Function:
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MKTLQSTLLLLLFVPLIKPAPPTQQDSRIIYDYGTDKFEETLFSQDYEDKYLDGKNIKEKKTMITLDEKSLQLQKDESVTPLTPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLKRLDFTGNLIEDIEDGTFSKLSLLEELTLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANTFKKLNKLSFLYLDHNALESVPLNLPESLRVIHLQFNNITSITDDTFCKANDTRYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPVGSYV
The following text describes a protein:
Function:
Acts in ubiquitin metabolism and is necessary for the control of single-copy DNA replication.
Miscellaneous:
MISCELLANEOUS: Present with 3270 molecules/cell in log phase SD medium.
Sequence:
MEFFYEEQVACIEDDKISNSHTKETGSTENTENNELQSRDDKTNEAFQKLEEEVNKRYEKTTSAFKKLVIEKDDGIEINLPISNETTETAQKYLKKLDENIHSVESLAQSYWSKMKTKNFWSGFSSFDNAAENDSNDKDENSKENEIAVGGNRTEAELRTLSKDKSVYLDNKMDLQLDPFDVDEKTEEICSILQGDKDISKLMNDIVPHKISYKDFWHIYFLQRNKILDKESKRKEILSKKEKETEEKEVEWDDEEEEEDDDKVEAVADNKSKGETKVAVSQEGLKDVSDHVGLANKDESKDDDDDDDWE
The following text describes a protein:
Function:
Functions in the SND pathway, a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range of substrate proteins to the endoplasmic reticulum. SND functions in parallel to GET in targeting proteins with downstream hydrophobic motifs.
Miscellaneous:
MISCELLANEOUS: Present with 195 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MDTVGTDAAAASINERRFAQSTSPKVSVKSQDSLFLITYSNMQQTVVQASLADRYPSLKKLNILLYIDIPTIDYYNDEMTHNKLSRLNKRFKLHRLRNSIAQSFSNTSTAEDNDKFWEELKSLISSRSTPENKFDLNVLVSSSGSLRYVETIRFLVEKLFNSFKDLYVQKKLNLCFQINVSPTSLKWFSTFLNAELLNLKIINWQNIGSFTKTIQNSKSLPFKEYYTKLNEKFTGSNQSNGSMQDQTVLDSIVIVTNSTGVKALLTLLSDHPLTSLISQESIKALHEYSDAVNEDKGDDQSNTSLKRNSSSLLNFQNSVLTSNKDKSVRIRSLSINRKSNRAHMFKTNESITTIPSTSINNLIGQESNLRKQPSGTALHLQSHLHPHSRSQSYSSSNMSRSPSPFPYGKTPSNDELVYDELNNQINEVQDRAKNEEIVLYNNNNYDDYTKERGEQEQDRTSYADEYGFNYDDEEGGNEDNYDDDEDDDDDDDDDDESDDEGLSFYAPSILSRSGSSTDVLSSGIDSMAKNSKETRGRFRSLSLMDPALQKPFNQKFPNSQQPDSAGASSPKRSTSSNHFTNVYVHDGDFDGTDTINNKKNLSSATLIKRKSLMNRNLAPSISNGLIPPEFISRISTPSTSASSSNSSLNDMSTVSNAFSKLLNDTSKKQKFLNSPIPQHTQQASPLLMRNNSNSNLLFEKNLINKSFEELRRQPSVNLFSTLMNGNMEKNGLALNFKSRTPTDALMANSIKNSNNSSHRLLNLEEEDQIMSGSLPKEREDDNDSTNSTIVPNHPDNDNYNDNDNDNNTGINSNNFNLNLYDDNDSAGFTDVTTEGVKYSNSNSTVTKPVYKKAVTLDLYGEDDMDNMGGWVLGGNAR
The following text describes a protein:
Function:
Catalyzes the deamination of dCTP to dUTP.
Sequence:
MRLCDTDIERYLDDGIISLTPRPNNDKINGATIDVRLGNSFRVFREHSAPFIDLSGPKEEVSAQLESVMSDEIIIPEGEAFFLHPGTLALATTLESVKLPANIIGWLDGRSSLARLGLMVHVTAHRIDPGWEGKIVLEFYNSGKLPLALRPNMVIGALSFEVLSGEXKRPYSSRKDAKYKNQQSAVASRIDEDKE
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MEVSEVPPEGGTPQLAKICGIQFGLMTTANTLNMSVLVTREGSIRSKDPMNAYFGLPTPSGKCLTCNGVTVDECQGHFGHILLSLPIFHPNYVEALVTLLRRICLNCGQLRKKSKLSSYHESSLALLAGADHQAQSNLGTHSNYQSHEPKGTECNTSNPVHADIGMSSESNSRNKRKLEEALDEDIDDWPDGLKPCISPEEVIVLSSDDSDEDFSGKAKELQGMETNCKTGQVTKCASPGIPTSSRKMLRKRKTVSYTEELNCKSPESEFAVPSKGSGSKAYKRRRTSMESRQTEKSRVILSGDTVEPASKSVKFATKVCKYCSASSRRLGYPKPDINVHVNLKGASNEDPFNSVKFIKMSVKPKERENLAADYWDFVEGSSKLEKPLKRGSRYLLPSEALNILKKIPQKSITALGMKANIACPEAMILECLPVPPNCTRLQEDAFGKGGTNLGFKIGVDRATQAFERLVRKINIIKTSRFGKPSFQAAVVECCVLQALFQQYLREKGAPKTAPGKEKKKVDTSGRLQHRPTRWSLDWLKKNLIGKRSGFSARNVVTGDPYLSVEEIGVPMDIAKHVTYSERVTDFNRSRLQEYIDIGQDLGKSMACGAVRIIRKDERREVTRKTEIDLQTGDIVHRHLKDGDLVFVNRPPSLHKHSLLALKANIHSGATWTINPAICAPLHADFDGDCLHVFVPQTEESRAELHQLMTIPAQILPSPDENTILGLSQDYVLATYLVTSSPLFLPKDSMHQLAMWTKKQLPVPTIVKSPKLGPLWTGKQVIDLAIPEGFSFQSNNGATRIHDGEILSCGEKSNWLASTKGLVRIIAQKNTDAAVEHIDCSQAVLREWLLSQGFSVSLEDFYAAPDQDMRRKLKYKIEDNLEHAQCMFVCRGDKKILNINTSSNASMSILDSAAPSERRRRRHGLEDAAISSFRQTQSQIGETFIESISDSNCLLTMVRSGSKGSNLKVMQQIGSLGFQVIKGEELLSTHKNPKLVRLAASMGYSMENDLQDIWEIRGLVKSSLLDGLEPHEFFVHAISVRDGLFRQSLDIAEPGELFKRLMLFLRDIHIAYDGTVRNMGGLEIIQFEYDGGKCMTQDSENKNTLSNKTVMPGDAVGILAATAISQPAYQVMLEATQCLASRKIRPLELLQESLFPRSTSKLKESDRVSILRLHRCKSDGKYCEERRVLKLQDELQPVTMEILATETAIAYSSDSSEQWEGLDCAATELKQTEFFPWVGHVQLDKMVLTEKKISQEMILDRLHSKVKIHKSVSRKFRIGNIVFCIRDSCTCDMNIYQETVKLRQKEVVGPCLHFLLTRSTRGKVRSIKTVKEVSNETVELLEVLQNFIIPEILKTVVKGSEKLQSVNILWEDATWSPPVKSEENDSNVMKSGRGELVLEVTVKELYSQSRGMPWRTVQESCIQFVDYVDWQRSSPYSIQEIKSVLGVDAARDVLLQRLELAAGNSIGNKHLKLVADFMVYSGEVQGLTSYGYRDWMRSLKFSSPFTAGAFRAPIKHFLEAGRKGATERFSGVLASSVFGKKVPLGTGAVFDLNLNMETKFTSSSSTNLNSEGSAESDPGGSVDVLARLIELNTEIGVQDLSAKSEVDTYDGNNSCQVIEWGSSPGISKSEGVWDVKNNGPAKTAVDPRNRGDDQNNDAWGTSDNIPQWGAGVAGRDWPSVETLDPWGQ
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MNQVLRLANNVSQQSSSYEFEYLNKVFIGFKVKFLIQQSKPHHQLKSIRIFSYHERYIGGTQMIIMIYYIRKYVTYMSKNIHLFYQNTSNISKLRIKKQERNSQWQLIRIYQQLFMFRKQLKSVDDKKTNNQSPYRLNFFNNQIKNKRDQELGQVQDVGNKRRLKKKESLSISNTFHFDDQQPASFNSFFVHSQKKPQNRDKLVTEIGNCGSYRKRVETLHTQQFSDDDARLHPDRQNERLRLKLYFNFQKMQARLVNLINLIQQIDACSLNNYISEISSATIEIIGGHCRQFKRFMINECIGLVFYLMIKRGILQGIDLNKWEKLLIYSHQANTIQTISTLKLQIKGVQQYQHQFQQFQSMNPLIPNQIEKMNLLIEQNIDKLLKNTQDKQVQQHLQAYRDSQIDAAFQFYQQKLRVIIVNLERFLFLLPKSSTVYTLVLDLDETLVHFIEETQEVLIRPYTEIFLEQMGKHFEIVIFTAGIQSYADKIIDKIDVMNVVKHRLYRHHTFSQGNVMLKDLSTLGRPLSKTIIVDNNPYNFVLQPHNGIKIKAWVGDEKDRALVELMQYLIKLTKYEDIRIGLKELKANPHYFTTSF
The following text describes a protein:
Function:
Component of the GID E3 ligase complex recruiting N termini and catalyzing ubiquitination of proteins targeted for degradation. GID E3 is regulated through assembly with interchangeable N-degron-binding substrate receptors induced by distinct environmental perturbations. Required for the adaptation to the presence of glucose in the growth medium; mediates in association with the substrate receptor VID24/GID4 the degradation of enzymes involved in gluconeogenesis when cells are shifted to glucose-containing medium. Required for proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBP1), malate dehydrogenase (MDH2), and other gluconeogenic enzymes.
Miscellaneous:
MISCELLANEOUS: Present with 1500 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSEYMDDVDREFINCLFPSYLLQQPVAYDLWILYLQHRKLFHKLKNTNLINADENPTGVGMGRTKLTALTRKEIWSKLMNLGVLGTISFEAVNDDYLIQVYKYFYPDVNDFTLRFGVKDSNKNSVRVMKASSDMRKNAQELLEPVLSEREMALNSNTSLENDRNDDDDDDDDDDDDDDDDDDDDDESDLESLEGEVDTDTDDNNEGDGSDNHEEGGEEGSRGADADVSSAQQRAERVADPWIYQRSRSAINIETESRNLWDTSDKNSGLQYYPPDQSPSSSFSSPRVSSGNDKNDNEATNVLSNSGSKKKNSMIPDIYKILGYFLPSRWQAQPNNSLQLSQDGITHLQPNPDYHSYMTYERSSASSASTRNRLRTSFENSGKVDFAVTWANKSLPDNKLTIFYYEIKVLSVTSTESAENSNIVIGYKLVENELMEATTKKSVSRSSVAGSSSSLGGSNNMSSNRVPSTSFTMEGTQRRDYIYEGGVSAMSLNVDGSINKCQKYGFDLNVFGYCGFDGLITNSTEQSKEYAKPFGRDDVIGCGINFIDGSIFFTKNGIHLGNAFTDLNDLEFVPYVALRPGNSIKTNFGLNEDFVFDIIGYQDKWKSLAYEHICRGRQMDVSIEEFDSDESEEDETENGPEENKSTNVNEDLMDIDQEDGAAGNKDTKKLNDEKDNNLKFLLGEDNRFIDGKLVRPDVNNINNLSVDDGSLPNTLNVMINDYLIHEGLVDVAKGFLKDLQKDAVNVNGQHSESKDVIRHNERQIMKEERMVKIRQELRYLINKGQISKCINYIDNEIPDLLKNNLELVFELKLANYLVMIKKSSSKDDDEIENLILKGQELSNEFIYDTKIPQSLRDRFSGQLSNVSALLAYSNPLVEAPKEISGYLSDEYLQERLFQVSNNTILTFLHKDSECALENVISNTRAMLSTLLEYNAFGSTNSSDPRYYKAINFDEDVLNL
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB3 (By similarity).
Sequence:
MDAVIDTSVIIEIFRGNKDTLYQICDYNCKITSITVFELYCGNLKENEMIMIDSLPKLNFDDKSSKIAGNIFKKLKKEGKIPSVKDLLIASIFY
The following text describes a protein:
Function:
Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections.
Sequence:
MSEKSVEAAAELSAKDLKEKKDKVEEKAGRKERKKEVVEEEENGAEEEEEETAEDGEDDDEGDEEDEEEEEEEDEGPVRKRTAEEEDEADPKRQKTENGASA
The following text describes a protein:
Function:
Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body.
Sequence:
MQSTDLGSKESGKIWHRKPSPATRDGIIVNIIHNTSDYLPKVLRFLNVAFDSSGDCLIAGDHHGNIYVFDLCGNRFNLVQRTAQACTALAFNLHRKSEFLVALADYSIKCFDTVTKELVSWMRGHESSVFSISVHGSGRYAITTSSDTAQLWDLDTFQRKRKLNILQSVGIQKVFFLPLSNTILSCFKDNSIFAWECDTLVCKYQLPAPPESSNILYKVFAVTRDGRILAAGGKSNHIHLWCLEAKQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINIQTCKLLFEIGSLDDGISSSVISPHGRYIASIMENGSLNIYSVQTLTKEINKPPPPLVKVIEDLPKKKGNSGDLKVKVTSGRVRRPARSRESKIQTRILKQDLTCGFEKKENELSDGLNKKRLQILLKGYGEFPTKYRMFIWRSLLQLPENQTAFSNLIDKGIHVAFLNLQKKYPIKSRKLLRVLQRTLSALAHWSAIFSDTPYLPLLAFPFVKLFQNNQLICFEVVATLIINWCQHWFEYFPNPPINILSMIENVLAFHDKELLQHFINHDVTSQLYAWPLLETVFSEVLTREEWLKLFDNVFSNHPSFLLMTVVAYNICSRAPLLNCKRKDDFEYFFHHRNNLDISAVIREAYRLLDTTPADIHPDSMLDAFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQAVEEMQAEVDQQRVEDEAWYQKQELLRRAEETRREILLQEEEKMIQQRQRLAAVRRELKVKEMHLQDAARRRLLQLQQDQREMELRRLDDEIERKVHMRDREIAATAKDLEMRHLELESQKRLYEKNLSRNQEAVAKEMKENADAYRQKVDVEEHMFHRLIGTDQTQNQKIHKLIEENLAKAEQACLNTDWRIQALHKQRCSDLHRNECYQEIAKLLRKNRKKEIEVLNAMMEGEAKKWEEAEEKDFHLKSEKKTAALSDASRRWFLEKEIHDAQHPCDKVVPKGRDEEFASGCLPRASQLNDISEMESLTQISLNQRKMHWDAMEQDLMERVRNLRQRLVTQAQNRCQTPHLLAT
The following text describes a protein:
Function:
Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit Polr2A/Rbp1 and Spt5, and (2) degrading the exiting nascent RNA transcript via endonuclease activity. The integrator complex is also involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5.
Subcellular Localization:
Nucleus membrane; Single-pass membrane protein. Nucleus.
Sequence:
MPVRMYDVSPRVFCAMQNLDITLLASYPEAEIRPVLPSLVRMSLLSPLDNTESSMESRKEILAVLIGIEVVNSIVSYLQVNYHELENELKKELQARQKSAFFEGQQHEYGLQSGIALGFERADVARKVRVVLSEIFNLQQQVSEQKPAAHSEMLDDGIYLEEVVDILCIALAELPSLLNILELTDALVHVPNGHRIICALVANFPDCYRDVVSHVIANCDEDGSDGKHRLMLLMGLSEMNPSQALANRSMCVDMLKVPSFMLKLTLKHPEDLIAFLTGLLLGNDQNLRSWFAAYIRSSQKRKGDALNLVRVELLQKVIQTTTNAAELRDFNLQGAVLLRLYCALRGIGGLKFNDDEINALSQLVTSCPQATPSGVRFVTLALCMLIACPSLVSTIPLENKAVEWLQWLIREDAFFCKRPGTSTSLGEMLLLLAIHFHSNQISAISEMVCSTLAMKIPIRPNSTNRIKQLFTQDLFTEQVVALHAVRVPVTPNLNGTILCYLPVHCIQQLLKSRTFLKHKVPIKSWIFKQICSSVRPVHPVMPALVEVFVNTLIIPNPTGKVNIDHMHRPFTEAEILHVFRTSKLTFFAEELPPMAESQELNQIEVTCPLTAQLLMIYYLMLYEDTRLMNLSALGGRKQKEYSNNFLGGLPLKYLLQKAHHYHNDYLSLFHPLLRLIISNYPHLSMVDDWLEEHNLAQGNSTVVVSKHELKPETLDRALAAIQTKPHLAIRVFKQLLQMPPETQAQYGQQLVKHLPMVFAKSVPRYVKDLYNDIWLRLNAVLPTTLWIMSLRAITNGSDTMDRRTFANESLLEPMEVLSCPRFVFCSPYLLMILLRILKGSLAASKTYLNVHMQMQQKQVLDKNGMMQTDAIWEDLRTTLIASQESAAVHILLEVLDYIASKATDRVSHLELREIQGIIGTYVHQAFISEPSLAKLVHFQTYPKSVIPMMVASVPSMHICIDFVHEFLNVTEMEKQIFTIDLTSHLVLNYSIPKSLGVSKFCLNVIQTTLSMLTASTKCRFLRNVMPAMVRFVETFPILADDCVNILMTTGRILHSQSSLGMTTMEMPLTDSDKLCTYRDAQLHIIMIEDAFKALVTAVMKKSDLY
The following text describes a protein:
Function:
Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A).
Sequence:
MPNNSKHKKKQQRRQQEAQKKSRAKQIETDKKNDEFLDTELDEVSPLVIDDDMTEFKNMPKVELHAHLSGSLSPETIKLIMESDETRAEEIMKKYKLEKPENMTGVFDCFPVIHAILRKPEAIRIAIRQTIKEFEEDNCVYLELRTSPKETDFMTYEDYLQVCIESFEAAKHEFPRIKTFLIVSLDRRMPFETAAHILGLIGEAQQRTNVIVGVELSGDPHLDGRRLLKLFVAARRFHGLGITIHLAEVLQNMADVEDYLNLRPDRIGHGTFLHTDPYTEYLTNKYKIPLEICLSSNVYSKTTTNYRNSHFNYWRKRGVPVFICTDDKGVIPGATLTEEYYKAAITFDLSTEELIGINQDALLNSFAYKYNVTDLTETFRKINNNVLD
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MQPTRILQGLKYRKLRLTTKDVNKGFYKGNRTGSMGTHTSYGTYKIDYTKVRTYVCPDLTGFKLTPFVSKTIRPVHDQFPGDKLGPKNPATYLARWKSENGLD
The following text describes a protein:
Function:
Aquaglyceroporin that may modulate the water content and osmolytes during anhydrobiosis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MCKRFRVPSLFRAAFAEFIGTYILVVIGNGSIAQSQLTNGEKGDYFTINWGWALGCSLGILISANISGGHLNPAVTLALALVRHFPWKKLPVYWCAQYLGAMAASGTVLGVYHEGKVDGEFRIRKNITEPGMASIFANYPAPYSSASIGLVEEILSTMIFMLVICVVTDKRYSNVPNFLQPLYIGFTLLAIGVAYGSNGGYALNPARDLAPRLVTFLGGWGLGVFSFRGYNWFWIFLVGPHVGALLGVGVFHIFLKTELTDWAPERVSSSSLKRPEKPIGAYKQSEFGFPSSLWHLQPLNNNNLVDSSKIMMPISRSGARRTSQISTRWI
The following text describes a protein:
Function:
Involved in the degradation of glucose via the Entner-Doudoroff pathway. Catalyzes the dehydration of gluconate to produce 2-keto-3-deoxygluconate (KDG). It is not able to use D-galactonate as substrate.
Sequence:
MASAMASSALREATCTMTRLAADVAASVSSIFSCKDSAGPRPVVPATKTTSTPLDVMFFTWFAKSSGSSLPPLKVVMTGATISIDSTRGALKKLARKGIKGWLNQYMATIKEIEPIVLYEQETDARWASYSILVRVVTSDGRVSYGEAVPTLRILPVVSAVRQTARAFLGRDPHEISAAFYEWYRQDFFLSRSFESATALSAIDMALWDLKARELGAPLYELLGGKLRDRVKVYANGWYGGCRDPQCFAEKAKEVVARGYDALKFDPFGPSFNSITSEELRRAEEAVAAVRDAVGDDVDILIEHHGRFNANAAVEIAKRFEPYRPYFMEEPLHHEDIEGYRKYRSLTSARIAMGERLISAKEALQYLVEGLVDVIQPDACNIGGVTGSMKVAALAEAFSVEVSYHNAYGPVQFALEVQLSAVTPTLYRLESFYDYWPQWKRDLIGDPFRLSQSSVEVPRGPGIGVAVNERVLEKYRAEPSEIPVGEEPVWVVRGTWR
The following text describes a protein:
Function:
Specifically inhibits C-type lysozymes.
Subcellular Localization:
Cell outer membrane; Lipid-anchor. Note=Anchored to the periplasmic side.
Sequence:
MTMKKLLIIILPVLLSGCSAFNQLVERMQTDTLEYQCDEKPLTVKLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVFWSKGDEATVYKRDRIVLNNCQLQNPQR
The following text describes a protein:
Function:
Regulates macropinocytosis in pericardial cells.
Subcellular Localization:
Cytoplasm.
Domain:
Has been proposed to contain 7 WD repeats. This prediction could not be reproduced.
Sequence:
MSADSPRRHPSGVVGSGIGLGSGSGTGLGSGSTGGSKSGAAVPAIVPPQTVSDRSILDSAIGFINDVTLANQPVQDPKDTITWARFETCADVSDPRFGDDWELEGNAAPPLLLILGYGLGVQVWAIPANGEAVEVLSWRHGVVTALRVLPTPATAAALDENGRADEPVDSFAEKRPLVAFVDGGSAAASGLLAGSSGLGLGGGGGGVTTVGGSVGGVSGIGVSASAQFSAVNFMSLKTGVQVKTIKFKNAVLDIQANRSAVVITFHERIAVFDARTLEDRLTITTCYPSPGINPNPIALGPRWLAYAEHKLLHSKRSGGGCDGEGVPSYTATVLNAAKSLSKGLREFGEQVAAGLTGTTAGSGASSKSSSFDSASGGPDAKQSGVVTIIDVKHPVKDYSPTSGTPLSSTAGSQGGGDPIVAHFVAHSEALVAMEFDSSGMLLLTADRRGHDFHVFRVQPHPVGPSLAAVHHLYVLHRGDTSAKVQHIAFSLDSRWAAVSTLRGTTHVFPITPYGGAMGVRTHTSLHVVNKLSRFHRSAGLGADGRSSSPISHSESTTFVQSLQPYHNPTLPPYPRPSVVQPLAQLRQPFTLGSPPGSAGLGGGVGGGGVMGSGVSAGGHGVGVGVGSNSQRQRQRLSSLSDDSGKPLSVCSIFAKSRSWLLEPPMATREQPHRVQRKAVDSLFVMAGHGALIQYDLDTKLASHVAKEKICDDTPIELEVEARAQWNLGRRKDGSQEIAPPLGLDNWLIKDRHASLLLDSANQFDDPDERTESWLAQVEIITHAGPHRRLWMGPQFVFKNYNTPSGSNLNHVDAEAVEIGVSKTTTTTLPSTAASSALGLGTIIGKDRSSPLNMPLSAATSVGGAGIGSSAVTGRSGAGVPVLIESGSYSSIEQSPKLMDRFRHGHLDSDYGHGDTRLKEDLADAMRESPSTAAARRETTGNYFTTDQLDGLALNNNNNINNNIIPTKDNASPNPNTNTNPNAIPSSNKVQKAEVTDAVDYPIRHSYGDHGELSTVVNIEVFDDQLSMSSISTNSRLSLEGPPSQSSPPLSLTNGLMDTNLMHFSESVTGTGVAQAQVHGRGANRFEVDDDDEEEEEEEEELDEEAEPDDDEREDRPLGRRNL
The following text describes a protein:
Function:
Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It can use a variety of substrates including spermidine, spermine and N(8)-acetylspermidine, 7-aminocephalosporanic acid, colistin and thiamine.
Sequence:
MDYRIRTSRDEDAALLPAIERSAGESFRLLPELAWIADAGVAGVDFHRRLIERGSHWLAEDADGQPVGFLAAERCADELHIAELSIAQAHQQQGLGRRLLERAVTYAHASHCRALTLTTFCDVPWNAPFYARLGFQRLTWQEAGERLRAILGHEQEIGFAADSRCAMRLVL
The following text describes a protein:
Function:
Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
IMWSLPAALLLLPLLLLGQAPPCRPQSPGPVKLRLVGPGSRPEEGRLEVLHQGQWGTVCDDDFALQEATVACRQLGFETAMTWAHSAKYGPGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVVCHPKRQRGFLSERVSNALGPQSRRLEEVRLKPILASTKRRSPVTEGAVEVKYEGHWRQVCDQGWTRNNSRVVCGMLGFPSDAPVISHYYRKVWNSKMNDPKSRLMSLTKKNSFWIHRVNCLGTEPHLANCQVQVAPAQGKLRPACPGGMHAVVNCVAGPRFRPPTSKPERKESPAEEPRVRLRSGAQVGEGRVEVLLNRQWGTVCDHGWNLISASVVCRQLGFGSAREALFGAQLGQALGPIHLSEVRCRGYEQTLGDCPSLKGPRNGCQHENDAAVRCNIPDMGFRNQVRLAGGRSPEEGVVEVQVEVNGVQRWGAVCSDHWGLNEAMVACRQLGLGFANHAIKDTWYWQGTPGAGEVVMSGVRCSGTELALQQCQRHGPVHCSHGAGRPSAGVSCTDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSQSANRMDWPYGHRRLLRFSSQIHNLGRADFRPKTGRHSWIWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGMQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGDYIFQVVVNPKFEVTESDFSNNMMQCRCKYDGQRVWLHNCHTEDSYRANAELSLEQEQRLRNNLI
The following text describes a protein:
Function:
Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
Subcellular Localization:
Apical cell membrane. Cell projection, filopodium. Cell projection, lamellipodium. Cell projection, microvillus. Cell projection, ruffle. Membrane raft. Membrane; Single-pass type I membrane protein.
Sequence:
MRPAPPPVMVLVLLVLSCRWGNRKASATSASPQSNSNPTQNDTTPSTTTTVASAITSITKASITIATTSASSTSIQTIPPTTIKSTKTVFTTTTITPTSSRATASSYLSSTKQPTSTLGSTSSSNAQSDTAGAKADNQSDVQAGGDSTQGVSSSATTQITSSATSSSVPISHSSGATAKSESTSTPLSISGAGGSQQVTTTKAGIPTTETTSVLQYTKLQNDTISKTPSGSPTSLTSSATVITITNITTTTASTLAAIPGSMSGGMPSTTSASPTNSTSVRHLGSSSPRPGTSPSSSPSTGSTTSTSPSDRDPPGSQPPRPAAPDNSSSTAVVNKVSCEVTNFITDEDLILEIEDPCSPLTGQENFQENQFHSTLCQLARTNFNKSRDQCLVRLGYQPGRRDQFALIEVSVKMNLGPQDLVEVLKDNWEDLKVVGVRNITYGGKLLEGEDEDRFSMPLIITIVCMATFLLLVAALYGCCHQRLSLRKDQQRLTEELQTVENGYHDNPTLEVMETSSEMQEKKVANLNGELGDSWIVPLDDLTKDDLDEEDTHL
The following text describes a protein:
Function:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MKIIIKTLSGQTFELEVQPTDSVLNIKEKIEKVKQFEIAQQKLLRKGTLLVDDQTVGDLGIQEKDFLVVMVNVKKGPPQQQPVQQQAQQPPQQPQPVQPQQPIEVPKPLNNPTTSNMVTGSEYDQAIQNLIQMGFAKSECEAAMKAAFNNQNRAIEYLLNGLPVIDQPPPQPALNANQVDQNILQLLREQFMQNPQAVLQSIQQLQQTNPQLYQQIQQNPETLIQLLMGAGQGEGDEIETEITQEEEQQLNQLMMMGFSKEDALEGFLACDKNVETAASYLFEKQARGDLLSQHYDREENNPENYNDEGNEGEENDQDDDDQYY
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MSSLYYANALFSKYPAASSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAETNFRIYPWMRSSGNAAHLTVSRAAVAPGTFPERRPLLGQVSLSASRVLPAGARPWGRGTPWAATRRAAPTPPPFLLGALRLPLLPRRISLRRRRGAPSPQPAPYPSSRPFSFKYLSTAPARAGDEAVCLSEEGWGLQRIAIRVSPSLLPSPAGDLSSGCVPQP