lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in control of the cell cycle.
Miscellaneous:
MISCELLANEOUS: Due to lack of HCF repeats, the cleavage process occurs via a different mechanism to that in the mammalian HCFC1; MISCELLANEOUS: [Isoform D]: Exons 9 and 10 deleted; MISCELLANEOUS: [Isoform G]: Exon 12 deleted.
Subcellular Localization:
Nucleus.
Sequence:
MEGSDFVDPAFSSGERISASDLNSEHIIQAENHSFANRISMDMDVPDGHQLDSNLTGFRWKRVLNPTGPQPRPRHGHRAINIKELMVVFGGGNEGIVDELHVYNTVTNQWYVPVLKGDVPNGCAAYGFVVEGTRMFVFGGMIEYGKYSNELYELQATKWEWRKMYPESPDSGLSPCPRLGHSFTMVGEKIFLFGGLANESDDPKNNIPKYLNDLYILDTRGVHSHNGKWIVPKTYGDSPPPRESHTGISFATKSNGNLNLLIYGGMSGCRLGDLWLLETDSMTWSKPKTSGEAPLPRSLHSSTMIGNKMYVFGGWVPLVINDSKSTTEREWKCTNTLAVLDLETMTWENVTLDTVEENVPRARAGHCAVGIQSRLYVWSGRDGYRKAWNNQVCCKDLWYLEVSKPLYAVKVALVRASTHALELSWTATTFAAAYVLQIQKIEQPLNTSSKLLSNNIVQQGTPTSAETSGINISANRSGSALGLGVEATSTVLKLEKESLQLSGCQPETNVQPSVNDLLQSMSQPSSPASRADKDPLSSGGGTTFNLSTSVASVHPQISVISSTAAVTGNDTASPSGAINSILQKFRPVVTAVRTSTTTAVSIATSTSDPLSVRVPSTMSANVVLSSSSSTLRIVPSVTASHSLRIASSQASGNNCRSSSAINILKTALPNVAVQSQPTSSTTTSIGGKQYFIQKPLTLAPNVQLQFVKTSGGMTVQTLPKVNFTASKGTPPHGISIANPHLASGITQIQGSTVPGSQIQKPIVSGNVLKLVSPHTMAGGKLIMKNSNILQMGKVTPNVMGGKPAFVITNKQGTPLGNQQIIIVTTGGNVRSVPTSTVMTSAGGSASGTNIVSIVNSTSTTPSPLQALSGQKTLISNQSGVKMLRNISSVQASSSMAFGQKQSGTPIHQKTALYIGGKAVTVMSTNTSMAASGNKVMVLPGTSSNNSPATTTALSARKSFVFNAGGSPRTVTLATKSINAKSIPQSQPVTETNNHSVATIKDTDPMDDIIEQLDGAGDLLKLSESEGQHGSEENENNGENATSSSASALFTGGDTAGPSRAQNPIVMEHPVDIIEDVSGVSSTTDVNETAIVSGDTIESLKMSEKENDDVKSMGEKSILSDDCHQPTTSETEAATILTTIKSAEALVLETAEIRKDHTGCTIGSLKENQDENKKFKQRQESSPSQNIHQFQNVDGSQLEALASAALLQAATSDTTALALKELIERPESETNTRSSNIAEIQQNNVQSTLAVVVPNTSQNENQKWHTVGVFKDLSHTVTSYIDSNCISDSFFDGIDVDNLPDFSKFPRTNLEPGTAYRFRLSAINSCGRGEWGEISSFKTCLPGFPGAPSAIKISKDVKEGAHLTWEPPPAQKTKEIIEYSVYLAVKPTAKDKALSTPQLAFVRVYVGAANQCTVPNASLSNAHVDCSNKPAIIFRIAARNQKGYGPATQVRWLQDPAAAKQHTPTVTPNLKRGPEKSTIGSSNIANTFCSPHKRGRNGLHD
The following text describes a protein:
Function:
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MDVSAPFPAAPAAEPAQPSPAIMTSPAPVVTSTAPTTSLAPLPSAVAPSLPAPAAVAAPEASAPASVREDQVQNAVGFLSHPQVRGSTNTASKRSFLERKGLTAAEIEEAFRRVPEAPAAAPVAPTAAVAPAPAAQAQPSYALQPGLPQQQQQQQQHGALVTYVSPQQQQQQPQQQMAMVPQQPPGPRWSQIVLGIGAVAAAGWALQALVLPRCRALLDSWSAARREAEEQRNKELTAAVESLKGCQEELKTTTQALLEAVTLMRSERQEAHLQQLMLGGSAAGQSGSARAGAGSMYTYANGGHGHGHGHGAASGSGSGMMMTGSSIMAGRGGGGGGGGRDPDSLLNGPDYASLRAAAGSYTNAYPPDAPVHPYGGGGGGMGGVSAGPTGGSTAGGGGGAYGAVRNAAAGPYGAGANGGGTAASGPGSSSGGAYDMTYKFTPTSPKPPAGAAAGGPSGFGAVHPYGSSDRLYDPTAPQGGAAARSTDGLDSPGGGGGGGGGRTVPRAPPEQPAYPQSFHEVMEMVQQGITPPNVRTDIVDTPPDPTRPFSEARMNAPLKPWERAAAASGAGAGAGPGAAGGSSSGSSGLGVGSVLTFGPSGTSANSNSNGGGPGVGASPFGGGSGATPPPRVYGSYGWGVPEGAGGGATGGVGVGAGAGPLTGSSGAASGVGGSGFAARGADGSGAAGTGGAASTASSAAPGSGQGSGQAAGGGGAAAASSSSPVGVSVLPPANPAWRPPPPPARTVSSVAPPAAAAAPAAPAPPSAACGGGGVADEAAAGAAAGAAAGGAGSGLDGAGASSAGGAARMVGVFEKAAGAGAVDATAAPQPVPVPVLVTRPTPEPASAAVTEASAPAAAPVTPDAAASATAAAAGSAPAPVAAEGGAAEPTTAAAE
The following text describes a protein:
Function:
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTQPPQDQTSTTPSLPPHLDPTTYPRTLTSATHNIHLELTYSTLNPTVALEHTSSPAAGANVLFLGTTRNTFEGRAVSQLSYTSYPPLALKSLMSIATRAAEKFDLKGVYIAHRLGVVPISEASIVVAVSAGHRGMAWKAGEEVLEEVKEKVEIWKREEFVDGGMEWRENRERDAEGRLLSSTEGGK
The following text describes a protein:
Function:
Mitochondrial co-chaperone required for ubiquinol-cytochrome c oxidoreductase (mitochondrial respiratory chain complex III) activity.
Subcellular Localization:
Mitochondrion.
Sequence:
MLSFQATVRPLAVSSRLHSPAAHIWRRNAHTAAMSDDSLDQGSSSSYGDSASQPHLGKGKGRQDSLAQSYRFPEKGMNGGPPDPFEVMALDRSATQQEVKQQYYKLALLLHPDSSHPSSSPDHFATLNKAYNLLSKQSSRSAFLKTGYGWDVSTSSGGNQTWSDSLMRAEIARRRNGGAAAWNGASRRYRDSDAGRGAWGGFDGSQGWRPYEDPSKGFSPPTSGPAEERYMSNPRFLAVVGVASAVIAWVHWHRLGYAAETHRDMLDKQNIDASRALAQARYEAATHGHIRREQIRRRVREAEVLKELEKADQGHIAVAGPPTAYPPSHRE
The following text describes a protein:
Function:
Endoribonuclease required for chloroplast ribosomal RNA (rRNA) processing and essential for normal growth and development. May be involved in maturation of both the 5' and 3' ends of 16S, 23S, and 4.5S rRNAs. Cleaves chloroplast rRNAs, mRNAs and tRNAs in vitro.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MLSRVCPTLRYNRIWSAHAREMPRATLLLLQPNFFHSSPKTALVNRLDVTSSEFSSMFRRSFHALRSTVGDWRKLPKPPGQVFAERREYRKIRRRAPKKKQELELSVSICIEEQLPDDLEIQNIAEMLRLNVPMAMTLAFNGLKDSKYKTRETDIEDLGGYETVELSVMLCNDDFICKLNKEWRGEDHATDVLSMSQHVPELKLPVLMMGDLVISVETAARQAAERGHTLLDEIRILVIHGLLHLLGFDHEISDEAEQEMEEEEELLLKNLGWKGKGLIQSAYDIQKTTTVQPEKSDDRKEGDGLRLYKPKFSYIFCDMDGTLLNSKSQISEANAKALKEALLRGLKVVIATGKSRPGAIRILKTADLTGSDGIISESSPGVFVQGLLVYGRQGKEVYRGNLDRDVCRETCLYSLEHRIPLIAFSQDRCLTLFDHPLVDSLHTIYNEPKAEIISSVDQLIAEADIQKVIFMDTTEGVSSVIRPYWSEATGDRANVVQAQSDMLEIVPPGTSKGNGVKMLLNHLGVSPDEIMAIGDGENDIEMLQLASLGVALSNGAEKTKAVADVIGVSNDQDGVADAIYRYAF
The following text describes a protein:
Function:
Transcription factor. Interacts, when in complex with WRKY71, specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Represses specifically gibberellic acid (GA)-induced promoters in aleurone cells, probably by interfering with GAM1.
Subcellular Localization:
Nucleus.
Sequence:
MEGVEEANRAAVVSCKRLVARLSLSAGDPFRLAAVAAETEEAVSRFSKVVNILGNRVGHARARVGRRSSPPADPIARCLLEYHPPPPVPYCPPASAPQLHGSSSSTPAPPPTPLKQMPVPVAAAAPCAAGNGKVVAPAAKGAADRDMFFQTPLLDLSACSSVTPASIAAAQINGSRLSAAPAAKAPDRDMFFQTPILDLSGCTPASIAAVQINGSRVSAAPAANPPPAPPPPPQIQFHHQIPQQQQQQQPQKRILEQQQRPASSDNKRFHFEPKPASEKPFHIEIPAARSGKEPEVITFSFDNSVCTSSAATSFFTNMSSQLITMSETSACAPASRKAAHKADDDGKCHCPKKKKPREKRVVRMPAVSDKVADIPSDSYSWRKYGQKPIKGSPHPRGYYRCSSIKDYPARKHVERCRGDAGMLNVTYENDHNHAQPLDLATLTANSEA
The following text describes a protein:
Function:
Major regulator of short-chained aliphatic glucosinolates (GLSs) biosynthesis. Together with MYB29/HAG3 and MYB76/HAG2, promotes aliphatic glucosinolate biosynthesis but represses indolic glucosinolate biosynthesis. Prevents insect performance (e.g. lepidopteran insect Mamestra brassicae and Spodoptera exigua) by promoting glucosinolates.
Subcellular Localization:
Nucleus.
Sequence:
MSRKPCCVGEGLKKGAWTTEEDKKLISYIHDHGEGGWRDIPQKAGLKRCGKSCRLRWTNYLKPEIKRGEFSSEEEQIIIMLHASRGNKWSVIARHLPRRTDNEIKNYWNTHLKKRLMEQGIDPVTHKPLASSSNPTVDENLNSPNASSSDKQYSRSSSMPFLSRPPPSSCNMVSKVSELSSNDGTPIQGSSLSCKKRFKKSSSTSRLLNKVAAKATSIKDILSASMEGSLSATTISHASFFNGFTEQIRNEEDSSNTSLTNTLAEFDPFSPSSLYPEHEINATSDLNMDQDYDFSQFFEKFGGDNHNEENSMNDLLMSDVSQEVSSTSVDDQDNMVGNFEGWSNYLLDHTNFMYDTDSDSLEKHFI
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.
Subcellular Localization:
Cytoplasm.
Sequence:
MADENHPAHLSPSELGTKNYWETYYARTLAHLSSKHQPNARPTPTADADADSAESESETESVDDDDDPGTSWFSEHKAPEKVLRFLTDESFPLAPCNTLPATSTAKTAAKKPQSDEERGRQPSILDLGTGNGSMLALLRKRGGFRGVMVGVDYSARSVELARELQRLKIHSAYLSGSESEGEEQEEGEEEDVVVSNGAETAEAIPVPEEDKDMMIRFEEWDILNSEGQLEGEGRLDWFPYAQGGFDIVLDKGTFDAVSLSEEVVVEGKSEGKVIQRRVCERYPSIARRLVRKGGFLVVTSCNWTEEELVRWFTGEEAKGPGADRLEVWGRVEYPKFRFGGQEGQGVCTVCFQRVD
The following text describes a protein:
Function:
Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
Subcellular Localization:
Nucleus.
Sequence:
MAIPPRWLNCPRKSQVIADRFFAFKTPLSSRYDDQIPEANRFQLPMLCSYFQTLKVKVGLIIDLTNTNRFYDKNELERLTGIKHVKLQCRGHGETPSPDQTQLFINICCRYWDKNPGELIGVHCTHGFNRTGFLIISYLVEKEDWSIEAAVECFTKCRPPGIYKQEYLNELSRRYGDSADPPSAPELPDWCYEDEGISDKDEEDGEEEDSNNAGPGNRRKKRRKAPGFPLKAAKFVDGVDGVEVVPSPKCEEIQDMCQEMCKFELNGFPGSQPVSMDRQNIRFLHEKDYRVSWKADGTRYMMLVVGEGQVYLIDRDNAVFSAPQFRFPQRKNPREHIFDTLIDGEMVFDKEGDKIHPRYLAYDIIKFQVPGKIVPGHAPCATCFDVQQGLLNKTQEPFSIRAKQFFPLEKTAWILEHWVPKLTHENDGLIFNPAEDPYLPGRQASVLKWKPHTLNSVDFILKIATVKQEGCLPRSVGYLMVGGFDRPFAEIKVTKELKAYNNRVIECTWDNKEWKFLRVREDKSHANAYTTAQGVCESIRNPVTKEWLLEVIEKYRFRKDNHHHRPHQHHQQQHHHSQQQHRPHPAQAPS
The following text describes a protein:
Function:
RNA-binding protein involved in gametogenesis in both males and females. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and promoting the translation of key transcripts. Establishes oocyte polarity through interaction with Bucky ball (BUC) (Probable). Interacts with Bucky ball (BUC) mRNA to mediate Balbiani body formation and oocyte polarity during early oogenesis (By similarity).
Subcellular Localization:
Cytoplasm.
Domain:
The DAZ domain is essential for the translation activation activity.
Sequence:
MVQGVQLPVCLICGLYSQDIQKHRQGFPSSLKLSNGYILPEGKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKGYGFVYFSEDVDIQTIVDQPISFKGKKLKLGPAIMKERSSRSVSSPMIGPSQWVNPTPYMYCSCCPPGLAPPSPVFSGGNQYMQPYSYSSPPGIMVPQVPMNYAQTTYAYQYPLPQWCGEQRTRLVNQNFVDCGVQTLLTLM
The following text describes a protein:
Function:
Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (2',3'-cGAMP) from ATP and GTP and plays a key role in innate immunity. Acts as a key sensor of double-stranded RNA (dsRNA), the presence of dsRNA in the cytoplasm being a danger signal that triggers the immune responses. Directly binds dsRNA, activating the nucleotidyltransferase activity, leading to synthesis of 2',3'-cGAMP, a second messenger that binds to and activates Sting, thereby triggering the immune response via activation of the NF-kappa-B transcription factor.
Sequence:
MVDAMNQEWWKKASDVVNAFHKEKAAIPSNAQRAREDLKENIAFLRTYLEFNYNLCDKVVFSGSAYEDLNISGDNIEFDVMLIAQRSNFLYLTECNNGVCKIRSNSPFLNYPFDEDFNIDSEKYRSFFFGLIQKWSNMMMTHKKKSFTLVNHGVATQMNVNDEKGILWYQVDLVPCFEAKSSLISEEKFYCVPKPIPNQRLYWRLSYSIDETQIAKKLSNDAKKCIRIIKALFKLETNGLFTKFTSYHIKTSAFYLKERGNWPNEENLGRSIYDFLVFIKESLKNGELKHFFDRTINLLDKIEVSTEQLANTINGWLKNEQKFLTKFSSSIDANIKQLAIK
The following text describes a protein:
Function:
Catalyzes the oxidation of 2 molecules of thiosulfate to tetrathionate.
Subcellular Localization:
Periplasm.
Sequence:
MKIIPYRKRSVLIATIFAISAVGITGCSDNTETKAVERVEEAAALARVKDLEARAEALKSNMPAANDMTATAGGTDTASGKPTIKMPDESTIPDDEFGAAVRRGLQISNHTYKELPNNVGNQLNCTSCHLGNGSEAYAAPWNNTPSVYPNYSKRTGRINTIQERINGCFERSLNGKALDLNSDDMNAMVSYMSWLSQDMPFGVSPEGSGFVKVDKTLEPNTDNGKKLFAEKCSVCHGATGEGQYNDDGTYVYPAIAGDKSFNDGAGMARTYTAASFIKGKMPFGQGGSLSDQEAVDIASYFTHLPRPIKANKDKDWPNGDAPKDVRR
The following text describes a protein:
Function:
Suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells.
Subcellular Localization:
Nucleus.
Sequence:
NGGSRRERASAGGGSTEKAFMTCYSEVLQIDPEVTDEEIKKGFRQLPILAHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKEREKQLKKEGKPTNVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKRERERQKNSEESRDANTKGKKEKKNWTFLRPPKVKMEQRE
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil.
Sequence:
MEPYVQNGLRKLAPYWNTRSSFVKGRWYGRTLAQVLMEEFHFSSEQVQAKILAGHCQLLRDGVVLNANTELIKNKDVFQSKQHNHEPPVLQWPLLHNVAHNTAGLKVVFEDNDLLVIDKPCGIPIHPTAYFYKNTLTEVLEDARGYPLFPCYRLDKITSGLLIFAKTQQTASRLQSQIRDQNMNKWYLARVDGNFDFNKKTASSPIYTFEPKKSLKGAFAPVRDALTEFYHVAYNEELNQSLVLCKPLTGRTHQIRIHLARLGHPIVNDPFYNVKNSKYPKRSAFMLEVEDWNTIEQDKLSHLFDEFIVEIDENWRGLNPAGDLCEECGEELPRDPEKHELILYLHAWKYNGSDISFTTEYPEWASAFEFGEIDIGRPDIY
The following text describes a protein:
Function:
Catalyzes the lipoylation of proteins, such as GcvH (SAV0833) and GcvH-L (SAV0324), likely via the ATP-dependent activation of lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domain of the target protein.
Sequence:
MKFISNNNITDPTLNLAMEEYVLKNLPAEESYFLFYINRPSIIVGKNQNTIEEVNQTYIDAHNIDVVRRISGGGAVYHDTGNLNFSFITDDDGNSFHNFQKFTEPIVQALQSLGVNAELTGRNDIQVGQAKISGNAMVKVKNRMFSHGTLMLNSDLDEVQNALKVNPAKIKSKGIKSVRKRVANIQEFLNDPLEIEEFKKIILKTIFGETEVEEYKLTDEDWENIEKLSNDKYRTWAWNYGRNPKYNFEREEKFEKGFVQIKFDVKRGKIEHAKIFGDFFGVGDVTDLENALVGCLHDFEHIEEALSEYDLYHYFGDIDRHELIRLMS
The following text describes a protein:
Function:
Transcriptional repressor (By similarity). May have histone methyltransferase activity (Probable). Negatively regulates shh signaling activity in pMN progenitor cells which prevents their switch from motor neuron to oligodendrocyte precursor cell production. Independently of shh activity, also regulates oligodendrocyte formation.
Subcellular Localization:
Nucleus.
Sequence:
MEHSIFPRSLWTNDSKILHHHVADFFSSVQVTQDIPAGTSFGPCVLHNTFYDTIAFIALKSFDKRNKSYVFRVDPEAMKGSPLVVPWLRLVQAAMSEEDQNTEAYLKGGQLHFRTIRDVKEGEELLVWYDEELSHLLGFRDIKAKALTDGYTCTRCGQAFKNENPFLAHCRFLCTQEKVDIIRPINQQKPEVKRHRKVIDFHNIARDLEDKMNTSSFEDTTILRKRKQEPFLTPKSKKTVLLEKTNITNESNTTNANKDCRAFRDLSEPTDNAQTNESKISKNSAFTEVRKAPEPSNPEKSSRDIMAPEVGLQSNCSAFSFVVPKSARSEQKSAFCEPSKRALAEAQNPSPPDTDNSLDSFKSKSSLGYRNVLASHLFPTDLAGSHSGGGMSAPLTSGGSYYYAPEHWTRAIGGQLQSTSSLTLLPPTFTPLGVSVQNWCAKCNLSFRMTSDLVFHMRSHHKKEFAAEAQVRRRREEKLTCPICHEYFRERHHLSRHMTSHN
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MYRNKLKSLCCFCENYFYTYKCSHLNNLNFIYFTTYYNFMNLNVSKDVNNYMKINGIIKKVDIKRYYNKKLNNWSYEDNAKEFDKKDEKEYGSKYEYNNKFINEEEKKDEEKKYRYDEKIHKGLYSEDNSTSMNNRYNNNESTYKMPKEILNRHEKIDLNSLPIDEEIINNLKIILNIEKLYMYQYIIYNEILKNSKHLLIYNKTGTGKTLSYLLPLIQKLINDKFDCNKKVLIITQNIYLCKQLYIYILSIYPTLNVCILSDEKESYNMNNNINNDIIVNIKRNNINPNDKENNDMCDEKYGIHFYLCTPNKLEYFIKNYKNKSRNDKNVMNNILNNINTIVIDEFDYIVEYRKNILNFFFKKDLFNEIHNNNNIRDKNRFNHDIFNKSNYNIYLFTANINEVIKKKIYEHLNGFVFFDFINGIKEHIQKQVAEQHNFNIDVLKNSENVVQLLNKENKNESLCNLNITHFVCKINSASKYKYVCYFLEEFFFHKQKISQKVYNDMVYDEYDKLNYRNMIPMEENKFVNNSEKEGNMKRSNADKINKCIIFANTKEEVEKLYEISLLKPHAVMMHSELLTIQKNENINLFKVGKKNVLITTDIISRGLDIDNVIFILNYSPPTSPNDYIHRSGRTGRGKEKGICLTMYHKYEYRNVDKIMKYTKNKFEVILCPKVEDVYKFSVDKLVENVMKIAPEKYEFFNEKSKELLKKHNTKIIAQILSILLKFDKKSFDVSLLSGKKNYVAVLIKDPFFEVIKNRDDIINIIKVITGNKIITTIIGDVAKCDEGFIVDISSSHVNKIISLFNSSNFEYKSKGLEINTLIELPPIIKEKKNIIRRKKKAPWITYKLQKKKIIILGRKTEKYKRKRAEDIIKDINRNI
The following text describes a protein:
Function:
May act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Subcellular Localization:
Cytoplasm.
Sequence:
MYYYLEIECESPVKDIFTCNKRRASKVVGNSFGGDHFNFRLGEIKLLSMDFPSSKVPEVEETSLGHGVVHLYRVFPSESHEFDAPGLILAILAIPLYMSPSDVLGFLGEKHCKSIQHIRLLKTKDPNRIMALLKFKDQASVIRFYTEFNGKAFSQIDPETCHVLHIDKVNIKYPMESSDSSSTEQQLVGPSSKPFASTTPALIELPTCVVCLERMDSSITGLITIVCQHTFHCPCLQKWGNSSCPVCRYTQKVQSSEFQSKCTVCCYDKDLWICLICGNIGCGRYHDAHAKQHYVDTAHCYAMELETQRVWDYAGDNYVHRLLQSETDGKLVELSTDGKSSGWTGSSATESKLRDKMGLEYTQILVSQLESQRLYYESHLSNMSQKLSRVNEELVLKTKIATASSNANTDLRSRVDISESKLKKRDDKLKRVSSQLEHLKHNYEEEKSMNENLLVRIQTLEKQNTTKSDQIVSMQFQINDLNEQLRDLMFTISASQEIQKMGQSEELQNGTIVLPNNSTVRSNSVKSKKKKKKKPVVPSSSGSLGTD
The following text describes a protein:
Function:
Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).
Sequence:
MDEGMRNLNRNVLTYYASTIVREITSKSNPQKTAIFQRVKTMLSQGFYLCGRRYSFLAFSANQLRDRSAWFFAEHPKISVPSIISWMGRFTNKNVAKYAARMGQCFSSTYATVEILPSEVNSKLPDIERNGYIFSDGIGMISADLAIEVAEKLQLSVNPPCAYQIRYAGCKGVVACWPAKNDGIRLSVRPSMKKFDSNHTILEICSWTRLQPGFLNRQIITLLSSLKVKEEIFWEMQKEMLSRLDKILVDSDVAFDIITGSCAEAGNTAAIMLSAGFKPQSEPHLRGMLSSIRAAQLGDLRNKARIFVPSGRWLMGCLDELGELEQGQCFIQVSSPSLENCFVKDGPNFSDIKKNLQVIKGLVIIAKNPCLHPGDVRILEAVDVPGLHHLYDCLVFPQKGDRPHPDEASGSDLDGDLYFVAWDKNLIPHSKKSWMPMDYAPAEVKQLNRHIEHADIIDFFSKNMVQESLGEICNAHVVHADLSELGALDEKCLKLAELAAIAVDFPKTGKLVTMPYNLRPKLYPDFMGKEEFQSYNSEKILGKLYRQVDILSQGEFAGLEFVPEDIPYDTNLEIPGYEDFIAEAWNHKCSYDSQLNGLLGQYQVNREEEVVTGHIWSMAKHNSKKQGELKERLKHAYNALRKEFRNVFEHMDPDFDQLSIDEKNNMYETKASAWYQVTYHPHWVTRTVLELQKTDVVSNTVMLSFAWIAADYLARIKIRQRGMQHSRPTPA
The following text describes a protein:
Function:
Probable carboxypeptidase.
Subcellular Localization:
Secreted.
Sequence:
MENLVFLSLLLLVLLSPFSSANDILGFSSNPKFPKSQAEKLIRELNLFPKDAEPVNAVGRESPKSLVETRLRFPGIDYSDASVSVEDLGHHAGYYKIKHSSAARMFYLFFESRDNRKDPVVIWLTGGPGCSSELAVFYENGPFTIAKNLSLLWNEFGWDKVSNLLYVDQPIGTGFSYSSDKHDIRHNEEGVSNDLYDFLQAFFEEHPQFADNDFYITGESYAGHYIPAFAARVHRGNKAKEGIHIKLKGFAIGNGLTDPQIQYKAYTDYALDMGIIQKPDYDRINKVLPVCEMAIRLCGTDGTISCMASYFVCNTIFSSIMAIAGDANYYDIRKKCEGSLCYDFSNMERFLNQRSVRDALGVGDIDFVSCSPTVYQAMLMDWMRNLEVGIPALLEDEVKLLVYAGEYDLICNWLGNSRWVHAMKWSGQKDFQASLEIPFEVRDSHAGLVKSYGPLTFLKVHDAGHMVPMDQPEASLEMLKRWMEGKLVEGQDESEEPEKLVAQMPSLNPKFPTLQAEKLIRELNLFPKDAEAVNGMDWEGESTKKLVERRLRFPGIDYSDASVKDLSQHAGYYKLRHSLAARMFYLFFESRDSRKDPVVIWLTGGPGCGSELALFYENGPFTIAANMSLMWNDWGWDKISNLLYVDQPIGTGFSYSSDLRDIRHNEEAISNDLFDFLQAFFEEHPLFTNNDFYIAGESYAGHYIPALAARIHRGNKAKGGIHINLKGFAIGNGLTNPQIQYKAYTDYALEMGMIEKTDYDRINKVLPVCEMAIKLCGTDGTISCMASYFVCNSIFSKIMALSGDTNYYDIRKTCEGSLCYDFSNMEKFLNQKPVRAALGVGDIEFVPCSPAVYQALLMDWMRNLEVGIPDLLEDGIKLLVYAGEYDLICNWLGNSRWVHAMEWGGQLEFQAAPEVPFVIGDSKAGLMKIHGPLTFLKVHDAGHMVPMDQPRVALEMLKRWFENKLPENTPAESKEPEKRVAQM
The following text describes a protein:
Function:
Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction.
Sequence:
MGCCSSRSSDSPASRVTRWRSTGIVALRDARLKAVPNEVLQVGNTLRTLDLTNNKIVEIPQEVGTIVHMQRLVLAGNLIENIPANIGYLRNLKILTLDRNRITVLPEELCSLSNLQQLTLSQNSLLCLPKSVGDLSNMLLLNVSDNKLNALPESIGGCKSLEELQANGNAIEDVPSSICNLACLKSLSLNGNKIRQLPQNLLKDCKALQNLSLHNNPISMDQFQQMDGFAEFEARRRKKFDKQIDSNVMMSSTALDEGIDLR
The following text describes a protein:
Function:
Regulation of oxygen dependent gene expression. It modulates the expression of Iso-1 (CYP1) and Iso-2 (CYP3) cytochrome c. In response to heme, promotes transcription of genes encoding functions required for respiration, controlling oxidative damage and repression of anaerobic genes. Binds to the sequence 5'-CGGNNNTNNCGG-3' (By similarity). Is non-functional in terms of iso-1 cytochrome c expression in strain S288c and its derivatives.
Miscellaneous:
MISCELLANEOUS: Heme is an effector molecule for CYP1/HAP1. The HRM repeat region mediates heme induction by masking the DNA-binding domain in the absence of inducer (By similarity); MISCELLANEOUS: The sequence for strain S288c and its derivatives differs from other strain backgrounds due to the insertion of a defective Ty1 element in the C-terminus. This acts as a null allele in terms of iso-1 cytochrome c expression and beta-galactosidase activity. Also, the expression levels of ergosterol-related genes and ergosterol content are decreased in laboratory strain X2180 caused by the defective Ty1 insertion. The sequence of a wild-type allele can be found in other strain backgrounds (AC P0CS82).
Subcellular Localization:
Nucleus.
Sequence:
MSNTPYNSSVPSIASMTQSSVSRSPNMHTATTPGANTSSNSPPLHMSSDSSKIKRKRNRIPLSCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNELKKLRERVKSLEKTLSKVHSSPSSNSLKSYNTPESSNLFMGSDEHTTLVNANTGSASSASHMHQQQQQQQQQEQQQDFSRSANANANSSSLSISNKYDNDELDLTKDFDLLHIKSNGTIHLGATHWLSIMKGDPYLKLLWGHIFAMREKLNEWYYQKNSYSKLKSSKCPINHAQAPPSAAAAATRKCPVDHSAFSSGMVAPKEETPLPRKCPVDHTMFSSGMIPPREDTSSQKRCPVDHTMYSAGMMPPKDETPSPFSTKAMIDHNKHTMNPPQSKCPVDHRNYMKDYPSDMANSSSNPASRCPIDHSSMKNTAALPASTHNTIPHHQPQSGSHARSHPAQSRKHDSYMTESEVLATLCEMLPPKRVIALFIEKFFKHLYPAIPILDEQNFKNHVNQMLSLSSMNPTVNNFGMSMPSSSTLENQPITQINLPKLSDSCNLGILIIILRLTWLSIPSNSCEVDLGEESGSFLVPNESSNMSASALTSMAKEESLLLKHETPVEALELCQKYLIKFDELSSISNNNVNLTTVQFAIFYNFYMKSASNDLTTLTNTNNTGMANPGHDSESHQILLSNITQMAFSCGLHRDPDNFPQLNATIPATSQDVSNNGSKKANPSTNPTLNNNMSAATTNSSSRSGSADSRSGSNPVNKKENQVSIERFKHTWRKIWYYIVSMDVNQSLSLGSPRLLRNLRDFSDTKLPSASRIDYVRDIKELIIVKNFTLFFQIDLCIIAVLNHILNVSLARSVRKFELDSLINLLKNLTYGTENVNDVVSSLINKGLLPTSEGGSVDSNNDEIYGLPKLPDILNHGQHNQNLYADGRNTSSSDIDKKLDLPHESTTRALFFSKHMTIRMLLYLLNYILFTHYEPMGSEDPGTNILAKEYAQEALNFAMDGYRNCMIFFNNIRNTNSLFDYMNVILSYPCLDIGHRSLQFIVCLILRAKCGPLTGMRESSIITNGTSSGFNSSVEDEDVKVKQESSDELKKDDFMKDVNLDSGDSLAEILMSRMLLFQKLTKQLSKKYNYAIRMNKSTGFFVSLLDTPSKKSDSKSGGSSFMLGNWKHPKVSNMSGFLAGDKDQLQKCPVYQDALGFVSPTGANEGSAPMQGMSLQGSTARMGGTQLPPIRSYKPITYTSSNLRRMNETGEAEAKRRRFNDGYIDNNSNNDIPRGISPKPSNGLSSVQPLLSSFSMNQLNGGTIPTVPSLTNITSQMGALPSLDRITTNQINLPDPSRDEAFDNSIKQMTPMTSAFMNANTTIPSSTLNGNMNMNGAGTANTDTSANGSALSTLTSPQGSDLASNSATQYKPDLEDFLMQNSNFNGLMINPSSLVEVVGGYNDPNNLGRNDAVDFLPVDNVEIDGVGIKINYHLLTSIYVTSILSYTVLEDDANDEK
The following text describes a protein:
Function:
Chitin-binding protein that inhibits the growth of the fungal pathogens B.cinerea, F.culmorum, H.sativum and A.consortiale, but not that of R.solani. Induces morphological changes in the fungal pathogens F.culmorum, H.sativum and R.solani, but not in A.consortiale and B.cinerea. Has antibacterial activity against the Gram-positive bacterium B.subtilis, but lacks antibacterial activity against the Gram-negative bacterium E.coli.
Sequence:
MVNMKSVALIVIVMMAFMMVDPSMGAGECVQGRCPSGMCCSQFGYCGRGPKYCGRASTTVDHQADAAAAAATKTANNPTDAKLAGAGSP
The following text describes a protein:
Function:
Involved in autophagy. May be required to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre-autophagosomal structure (By similarity).
Subcellular Localization:
Endosome membrane; Peripheral membrane protein.
Sequence:
MDLYCQKCYKQLELDDSLLDIDQSLFLKTNIHEIIEELEELSLKPVPKERETLILKQQQQQLLQQQEQAAAAAAIQSPQTVSKMSKLKSGLFGKRKELTQSNSTTPTTPATPTATPTSSSLSLPTPPPLPQQQQQQQQQQQQTFNDQSKLTATTPTQPTPIEEKKQQSFKTFYPAAHSNNSSNGSDHGGNVNTTGVSPSSPGGGAHSFGSLSQHRLSSSLSLKSISSGGGNSSSNLVADINNNNNSVNKDNNTTISSSTVTTSNSISESNNQDSKLLVATTTTTTTTTTTTILATIPTTTTTSTPTTPSTVGGTTPSPPSSSSSSSSSSSVITSPISRISPSNITSPSKLSQQSTPRQRPLTIAPTKLNISQVSSPQKPRLKYLRTSSKSLSMASLPAVGPDGTIIVDGGASSGTESTSMTNHHSSFLNQSTLPLGSSPVQTTPPLLSNSMNNSTNNLQSLQQQQQQQQQQQQQPISENNYYKYMKGLSLFKIATDLINYDLPLCLECTKLTIGELEDEGSILDGEVSIYSAYLKQLEKGKTEEDLEELGKEMTLLCEEEEQLRLMIENTHQERKEVEQLTLQLQDRIATLKSLEDSYWSCFSEFHYETFRNKDERDQTTVQIQWVNDHLESLKQTNILNDAFHLWHDGHFGTINSLRLGKLPSQPVEWNEINAAWGLAVSLLDAMAKKLKFKFQQFTLVPNGSCSRVDKRDVDPPLAYELYGTNDISLGRLFWYRRFDNGMIAFLQCIKELCEHITEKDPEFSVPYKIDKEYIGGMCIKLQFTNDDTWTKSLKFMLTNLKWILIWIVKNETLTLFNNQQFQQSKLNNNQNNNNINNNNNNNINNNNNNNVNKRN
The following text describes a protein:
Function:
Assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor when interacting with candA-C (By similarity).
Miscellaneous:
MISCELLANEOUS: In E.nidulans, CAND1 is separated into 2 distinct proteins: candA-N and candA-C (AC Q5BAH2), corresponding to the N- and C-termini respectively of the protein in other species.
Subcellular Localization:
Nucleus. Note=Requires candA-C for nuclear localization.
Sequence:
MGDRHTIQQNLNGLLSKLNDPDPDMRYMSLNDLYGILSNPCSSYLAHDQASATRLAEGLLKALDDQHGDVQNQALKCLGPLVARLPLEGLRTLLERLSNLTTSQTIDTSVPNTALRVIVTALPRPQPNQAPSPDANMAYSAVSEVLIPRLIGPGPHKRRGSVTKGMLEKDPAKGFSSDAIDVLIQVASCFGALLQESELTALEKAVMSIIDNDTAGTVVTKRALAAISALVVYFSDEQFGILVSELVERFNSPQLSTVHRRHLIAAVGCLARTVPAKFGPHLSTLAPFIFSAVGEDNLEVSHVLHYLCTSASNVYSSRNKPKIYHQYRQLPKEKLITGM