lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Starch-binding protein present at the surface of the cell. Mediates starch-binding before starch transport in the periplasm for degradation. SusE and SusF do not constitute the major starch-binding proteins in starch degradation pathway. Has higher affinity for starch compared to SusF.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Domain:
The carbohydrate binding modules (CBM) mediate starch-binding.
Sequence:
MKKISNILLAVTFALPLFTACETDNDSNPILNEPDTFTLNTPAYAANNVYDLKNAQTVELTCSQPDYGFPAATTYTVQASFEQDFIEATDESKANYTVLESTSPTAKINVDASELNNALLDLWTAVNGEQAELPTEPVAVYIRLKANITSSGKGVCFSNVIELPNVLISKSTSSLTPPKTMFIVGSMLDTDWKVWKPMAGVYGMDGQFYSMIYFDANSEFKFGTKENEYIGINDNRVTVTDKAGAGVSGSDNFVVENAGWYLFYVKAAVKGDDYQFTITFYPAEVYLFGNTTGGSWAFNDEWKFTVPATKDGNFVSPAMTASGEVRMCFKTDLDWWRTEFTLHDGEIFYRDFNLIDSWTEKGDGYSIQGSAGNVIHLNFTAGTGEKK
The following text describes a protein:
Function:
Core component of the smc-5/smc-6 complex. Functions in DNA double strand break repair by promoting sister-chromatid homologous recombination during meiosis. Acts in a DNA repair pathway for removal of ionizing radiation- and ultraviolet (UV) radiation-induced DNA lesions that is distinct from classical nucleotide excision repair and the translesion synthesis pathway. Also involved in the recovery of stalled replication forks.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes on chromosomes during diplotene and diakinesis in oocytes.
Domain:
The flexible hinge domain, which separates the large intramolecular coiled coil regions, allows the heterotypic interaction with the corresponding domain of smc-6, forming a V-shaped heterodimer.
Sequence:
MASQDSDEALPANYKDYPDGSLLRVVFHNFLTYEHTSFLPTASLNMILGHNGSGKSSIICGICLACGGSPKSLGRSERIVEYIRHGCTEGYVEIAIADKQKGPQVVRLTIRVGEQPKYRLNDSATTQSEIADLRKHYNIQIDNPCAFLAQDKVKSFSEQSSIELLRNTEKAASADLDQQHIDLMKQREDSTSIEDKCTTSENAIKRLEDEIGKIMPLVENYRKKLALQSKLRLLEKKMKIMEFEKFDREYKAELQNMDGAMIEYREVEKSIAECEKHRKNLEDRIKKDRSQISQMQRSCNEILAKVQEKGDKKLMEDMMQRAKAKLESAKKAADQHEKDVEKARKMIDQARARLQEAVDTLNGYEEFQSEMKSLEQKYSTAERDSRQEEDAIQKKSYEMRQLENKKRDEEQNSQLNRQDRYRVLQNFSSDASKAYRWYQQNRSQFKGDVYMPIMDMVLKTPEAAKALENSVGVRDRTMFVCCYKEDELLINGKQHSWRINTSVVPAEKIYSEDIDAQLPSELSRLGFKYLVSNCFDAPAPLKQFLCNVSGLNRIPFGGSDVEKKIAEVSQAIEQTRYSVFLTANIRCQNSKSRYANNTLQSQSATREANTWRDQFFKVSPVAKRTDNSILEEIQKLKAEIDIRSEQLREKRGAIQKERDVLRQEQMQWKSKKQVHTKWKTELASEMAKLEALENEVVDISAIEEEYANVEKKAILETKKMLENSIRWHKEIIDKHRLIGIFELSESICKSRVNKSNSEAETHRSKLEDLKSVKDAAEDLLKTALNHKKAAASALMKECSLKTLDESKMSPAENKIYSSLVKMFEEADVPTDMNTLDQAITSEKTRLKLAEDSGEDGSIVHEQRLKVLDDDLVLEKTRQEKLIENRARIHDKLGDEINNWRKEVETMIEQINVNYVQFFDSLGCRGEVSLEVPENPLDIEKYGIMIMVCFRKGESMKRLDNKVQSGGERSVATMLYLLALQQLCPVPFRCIDEINQGMDPTNERKVFDIMVGMWNGTTGTLSKTQYFLLSPKLLHGLDMRENVNIVMVNSTLTNSHGKHYDTSAKIDATFAKMGISA
The following text describes a protein:
Function:
Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MARYYLSAMDVLYRLSIWVAGIALIIMVAAIPIGIFARYIQNDGLSWPEPVAILCMVTFTFIGAAASYRSGSHIAVSMVTDRIPEAGKKICALLVNLLMVMISLFILSYSYILCSELWSQPVAEFPLLTAGQTYLPLPVGSAITLMFIIERLFFGPQTQRPVVMIGNS
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Sequence:
MKYLIAGTGGVGGSIAGFLSLAGKDVTCIARGAHLQAIQKDGLKLKSDLKGEHTLVIPTMNAEEFNGKADVIFVCVKGYSVDSITELIKRASHEKTVVIPILNVYGTGPRIQRLVPGVTVLDGCIYIVGFVSGTGEITQMGKIFRLVYGAHKGTQVAPGIMEAIQKDLQESGIKAEISPDINRDTFVKWSFISAMAVTGAYYDVPMGEVQKPGKVRDTFIGLSTESAALGRKLGVEFPEDPVSYNLKVIDKLDPDSTASMQKDLARGHESEIQGLLFDMIAAAEEQGIDIPTYRMVAEKFTKH
The following text describes a protein:
Function:
Subunit of an amiloride-sensitive cation channel (degenerin channel complex) permeable for sodium, potassium, lithium and N-methylglucamine, and required for mechanosensory transduction (touch sensitivity). Interacts with degenerin channel proteins and stabilizes the channel. Plays a role in mechanosensory transduction (touch sensitivity).
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Cell projection, axon. Note=Co-localizes with mec-4 in puncta along the axons of touch cell receptor neurons and in muscles.
Sequence:
MGLQSAAAHFINRFIIWITIFMVACFLLRLLVVLDLNKRVYNHTPGPCRVLTDNYKGTAGMTYVESQKRVYITLGYGRAHDLKTKTGIAFYKTNRTDGRSQQEMYDLIEMTINWNGYEYKKEFIPTGIDSYSSSNGRVLLYVINAHPNHQCIHFFQIVESSKLNHRKAICDPSFSSLQDIAVVGPDRLFVTNMAAFGRGWAQILEFSLQTGQGAVYYYDGSKLSTAASSLIAPTGIGYDAKRRILYVGSMIRESIFAYKVAKDTTLELLYEMMLLTSPIGVFVESKTGDIWIAAHPVIHESAWHYTHPENQNIHSPSQILRIRIQEEGNSWVTTEPYANDGATISASSSVVFTDEQMLIGSSFGRLLHCDLTHSYIT
The following text describes a protein:
Function:
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr) (By similarity).
Miscellaneous:
MISCELLANEOUS: This protein is composed of two complete HPrK/P domains fused in tandem. This unusual organization may lead to a separation of the two antagonistic activities in F.nucleatum, with the C-terminal copy carrying the kinase and the N-terminal copy carrying the phosphorylase.
Sequence:
MYTYTTIREIVDKLNLEILNEGNLDLKIDIPNIYQIGYELVGFLDKESDELNKYINICSLKESRFIATFSKERKEKVISEYMSLDFPALIFTKDAIITEEFYYYAKRYNKNILLSNEKASVTVRKIKFFLSKALSIEEEYENYSLMEIHGVGVLMSGYSNARKGVMIELIERGHRMVTDKNLIIRRVGENDLVGYNAKKREKLGHFYLEDIKGGYVDVTDHFGVKSTRIEKKINILIVLEEWNEKEFYDRLGLDVQYEDFVGEKIQKYIIPVRKGRNLAVIIETAALTFRLRRMGHNTPLEFLTKSQEIIERKKKEREEYMNTNRLPVTKLINEFDLEIKYGEDKVSSTYINSSNVYRPSLSLIGFFDLIEEVKNIGIQIFSKIEFKFLENLPPIERVNNLKKFLTYDIPMIVLTVDANPPDYFFDLVSKSGHILAIAPYKKASQIVANFNNYLDSFFSETTSVHGVLVELFGFGVLLTGKSGIGKSETALELIHRGHRLIADDMVKFYRNTQGDVVGKSAELPFFMEIRGLGIIDIKTLYGLSAVRLSKTLDMIIELQAVDNSDYMSAPSAHLYEDVLGKPIKKRILEISSGRNAAAMVEVMVMDHMSGLLGEK
The following text describes a protein:
Function:
Protease required for deconjugation of smo-1 conjugates from target proteins which is necessary for cell cycle progression (Probable). Required for respiration and the maintenance of normal mitochondrial homeostasis. In response to mitochondrial stress, required for the removal of smo-1 conjugates from the transcription factor dve-1, which promotes the translocation of dve-1 from the cytosol to the nucleus to initiate the mitochondrial unfolded protein response. Furthermore, removes the smo-1 conjugates from the transcription factor atfs-1 to promote its stability and activate the mitochondrial unfolded protein response. Also plays a role in promoting mitochondrial unfolded protein response-mediated innate immunity following infection with P.aeruginosa.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Mitochondrion matrix. Note=Localizes around the metaphase plate and the pericentriolar region and in the surroundings of the central spindle. Translocates from cytoplasm to mitochondrion at late developmental stages.
Sequence:
MEVSTSYCTPAVNFKYGSFQDSDVSMREDDLFRMGSYNSQGYYADGTHLDGSIGEEDETSSGSNDQHMDFEEDDFDMESSMTEDLVDEDEEEEDEEDNDEWTNQKRTDNQNSVAYYAAMEMLRIRFPFQSIAIRISDFCCLQEKDLLNDTMIDFYLNHIVEHVLPDSNGSNVTVLPSIFWHNLSLRQHAFDSEDEKMMSDEQKMDLKFGDLHDFVADFDLQDFDYIVVPVNEWEHWSLAVICHPFTAQARTVIFDSQLTADLNNLQNMATLIESFMKYSYEKRTGNAMPFPLPCILPQRMPQQTNNFDCGIFIAEFARRFLLSPPKDLDNFDFAREYPDFSTATKRTEMQRVVLSLSTNRARWRPLVELLNGYSTAAPHRAL
The following text describes a protein:
Function:
Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus.
Subcellular Localization:
Nucleus.
Sequence:
MDGGDDGNLIIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQEPSSCKSLGNTSLSGPSIHCPSAAVCIGILPGLGAYSGSSDSESSSDSEGTINATGKIVSSIFRTNTFLEAP
The following text describes a protein:
Function:
Involved in polyamine biosynthesis.
Sequence:
MAEKNRLVTVAALQFACTDDVSTNVATAERLVRAAHQKGANIILIQELFEGYYFCQAQKEEFFHRAKPYLGHPTIVRMQNLAKELGVVIPVSFFEEANNAHYNSVAIIDADGTDLGLYRKSHIPDGPGYQEKFYFNPGDTGFKVFQTKYAKIGVAICWDQWFPEAARAMALQGAEVLFYPTAIGSEPQDDGLDSRDHWRRVMQGHAGANVVPLVASNRIGKEIIETEHGNSEITFYGYSFIAGPTGELVAAAGDKEEAVLVAQFDLDKIKSKRHGWGVYRDRRPDLYKVLLTLDGSNPVK
The following text describes a protein:
Function:
Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, differentiation, G2/M progression and cytokinesis (By similarity). Required for convergent extension cell movements during gastrulation, acting with fyna via rhoa. May be required for epiboly to occur, possibly through its effects in calcium signaling. During embryonic development, phosphorylates ptk2.1/fak.
Subcellular Localization:
Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Cell junction.
Sequence:
MGCVKSKEDKGPTQKYRPDPTNPTPGSHMGLYGPDPTQMGQSPALKGPTNNYNSRSSGLTPFGGSSSVITPFGGASSSFSTVAVNNPFPGVVTGGVTFFVALYDYEARTSDDLSFSKGDRFQIINNTEGDWWEARSINTGQKGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLLPGNQRGTFLVRESETTKGAYSLSIRDWDEMKGDNVKHYKIRKLDSGGYYITTRAQFDTLQKLVKHYTEHADGLCYRLTTVCPTVKPQTQGLAKDAWEIPRESLRLELKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEYMGKGSLLDFLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMRLCWKKEPDERPTFEYIQSFLEDYFTATEPQYQPGDNL
The following text describes a protein:
Function:
Required for differentiation of the phagocytic blood-cell type, the plasmatocyte.
Subcellular Localization:
Cytoplasm. Cytoplasm, perinuclear region. Note=Mainly around the nucleus.
Sequence:
MSLKLMAFVCALLLLCTLTHVLSAATTVRPYKFGFTIDEQQHRAEKRDERGIIMGEFGFITADGIYHVTVYATDEEGKFRIISMKSYPYAGPVGSKSVPVTTTPKVLLPAAPVALPKYNFNSEACSGCFLKKSPPKTEIRTLSQPLAPVQPGKPDGSSDIGLNVQLPFRESIAQTVASRLGLLQDTLQTSNTNTNAPNTKTIELGLNIAMSTYYTTKNAVTGHVSTQTSNSQTPSANTKIDYNVGVVEKASPPVYRPLNIRLNEDVMRQAITYGNTIPGHVPLPNQPLVETSLLPASQVKIFALDGNAKVPLASNIQSVAQHPNAGLNAKVPLASNIQSVAQHPNAGLNAKVPLASNIQSVAQHPNAGLKNINRSGVSSAKTLANTKTRPPHTFNPHQTPLLSSATAPGISGVTANTPTGNVPSNGGGIAAGKAPGNPQAGGSGGIIGAGAPGGRKVSAGGIGSGSAIGGVSGGSKASGNGGAIGSGSAIGGGATGSKASGFGFGSNIGGGVSGSKPSGFGSESKIGGPDSGSKALGFGSGSKIGGGITGTKASGFGGEIGSGRGSASSATGDLYKFKYILDYNGHEETGGRNGDKQGSYFAIGEDAVQRTIEYIANEFGFQPHVSWRKLDAKEALPEENSLKHYEFKWFNQE
The following text describes a protein:
Function:
May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell projection, axon. Nucleus.
Sequence:
MSSATSPIILKWDPKSLEIRTLTVESLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAASVEQATQNFLEKGEQIAKESQDLKEELISAVEDVRKQGDTMRITSSEFADDPCSSVKRGTMVRAARALLSAVTRLLILADMADVMRLLIHLKIVEEALESVKNATNEQDLAHRFKEFGKEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQEAIAGIANAAQATSPTDEKQAHTGIGELAAALNEFDNKIILDPLTFSEARFRPSLEEKLESIISGAALMADSSCTRDDRRERIVAECNSVRQALQDLLSEYMNNCRYGTWMDESCKSGRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLDATKLLCETVMPRFAEQVEFAIEALSANIPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLIAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGTAVQSTFTTFYEVAGDVIAGGRDSQLSLDLLPSCTEGSLFGSGSRDSTMLDSATSLIQAAKNLMNAVVLTVKASYVASTKYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEYQTRVRRGSQKKHISPVQALSEFKAMDSF
The following text describes a protein:
Function:
Involved in the organization of apical junctions; the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis (By similarity). Required for building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells. Seems to recruit INT to basal bodies of motile cilia which subsequently interacts with actin-modifying proteins such as DAAM1 (By similarity). In cooperation with INVS may down-regulate the canonical Wnt pathway and promote the Wnt-PCP pathway by regulating expression and subcellular location of disheveled proteins. Stabilizes protein levels of JADE1 and promotes its translocation to the nucleus leading to cooperative inhibition of canonical Wnt signaling (By similarity). Acts as negative regulator of the hippo pathway by association with LATS1 and modifying LATS1-dependent phosphorylation and localization of WWTR1/TAZ (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell junction, tight junction. Note=In the retinal photoreceptor cell layer, localizes at the connecting cilium. In cultured renal cells, it localizes diffusely in the cytoplasm but, as cells approach confluence, it accumulates to basolateral tight junctions. Localizes to the ciliary transition zone.
Sequence:
MGDWHRAFTQNTLVPPHPQRARQLGKESTAFQCILKWLDGPLIKQGILDMLSELECHLRVTLFDVTYKHFFGRTWKTTVKPTNQPSKQPPRITFNEPLYFHTTLSHPSIVAVVEVVTEGRKRDGTLQLLSCGFGILRIFGNKPESPTSAAQDKRLRLYHGTPRALLHPLLQDPIEQNKFMRLMENCSLQYTLKPHPPLEPAFHLLPENLLVSGFQQIPGLLPPHGDTGDALRKPRFQKPTTWHLDDLFFTLYPSLEKFEEELVQLLISDREGVGLLDSGTLEVLERRLHVCVHNGLGFVQRPQVVVLVPEMDVALTRSASFSRKISASSKNSSGNQALVLRSHLRLPEMVSHPAFAIVFQLEYVFNSPSGADGGASSPTSISSVACMHMVRWAVWNPDLEVGPGKVTLPLQGGVQQNPSRCLVYKVPSASMSSEEVKQVESGTIQFQFSLSSDGPTEHANGPRVGRRSSRKMPASPSGTPAPAARDLAATQDSPVGPGLSLSQLTASPLSPALQSSSKPPLQPPDSSQSPEGPQLQAESVLESRVSHLEADLSQPASLQGTPAVEHLQELPFTPLHAPIVVGAQTRSSRSQLSRAAMVLLQSSGFPEILDASQQPVEAVNPIDPVRFNPQKEESDCLRGNEIVLQFLAFSRAAQDCPGTPWPQTVYFTFQFYRFPPETTPRLQLVKLDGTGKSGSGSLSHILVPINKDGSFDAGSPGLQLRYMVDPGFLKPGEQRWFAHYLAAQTLQVDVWDGDSLLLIGSAGVQMKHLLRQGRPAVQVSHELEVVATEYEQEMMAVSGDVAGFGSVKPIGVHTVVKGRLHLTLANVGHACEPRARGSNLLPPSRSRVISNDGASFFSGGSLLIPGGPKRKRVVQAQRLADVDSELAAMLLTHTRAGQGPQAAGQEADAVHKRKLERMRLVRLQEAGGDSDSRRISLLAQHSVRAQHSRDLQVIDAYRERTKAESIAGVLSQAITTHHTLYATLGTAEFFEFALKNPHNTQHTVAIEIDSPELSIILDSQEWRYFKEATGLHTPLEEDMFHLRGSLAPQLYLRPRETAHIPLKFQSFSVGPLAPTQAPAEVITEKDAESGPLWKCSAMPTKHAKVLFRVETGQLIAVLCLTVEPQPHVVDQVFRFYHPELTFLKKAIRLPPWHTLPGAPVGMPGEDPPVHVRCSDPNVICEAQNVGPGEPRDVFLKVASGPSPEIKDFFVVIYADRWLAVPVQTWQVCLHSLQRVDVSCVAGQLTRLSLVLRGTQTVRKVRAFTSHPQELKTDPAGVFVLPPHGVQDLHVGVRPRRAGSRFVHLNLVDIDYHQLVASWLVCLSCRQPLISKAFEITMAAGDEKGTNKRITYTNPYPSRRTYRLHSDRPELLRFKEDSFQVAGGETYTIGLRFLPSGSAGQEEILIYINDHEDKNEETFCVKVLYQ
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MGKKNKSNGGGNTNNTPTKTPSKPPVKFNDKWASIENGEAKSASVSHYKEPSKEPKFVHPAKLAKEKKIFDGLDIPERVLAHGKVVEQNGGKKRRHREISPKMEAKKPKVESKSKDGVAAKKAHKHFTVSSEVVQSTYFFEEPDNGNEVTLVSNGKETTIEKTVILDEEVEDEEIDEEEFEDEEEVEDEEGMDEDETEIDESEMIVDPKDIERCIEFEDVDDEDEMEDEEEFEDEEEVEDEEVDDEEEEEVADEERGEEQEDEQEEEEEVSDEESVVSEMDADSDDEGFIAGKDREAHVISKDKAARTFAAKPVDFDAFPFNDQDSVVTASRAFGFMVSPCDVQTFFDKFYQSNVLVVHRKTPAYYGNLFSTTRFSELLEKHYLEYNMNINIAQYKDGIRTTLNGKGRVYPQIVKQHLHNLCSVQLVNPQTFDDRIWYLCEILQEQFGCFVGANTYLTPAGSSGFAPHWDEIDAFLLQVEGRKYWRVWAPESAEEELPLESSGNFTEDDMKGKEPVFEGWIEQGDMIYIPRGYTHQARTDKKVHSLHVTVSTGRQWSFANLMEKVIPEAVGALTEERHKLRRGLPIGLFDMGGVVDLDYSQEEHFTEKFKIVVDRHMSRLRNLVADHLLDSSVDSMTKEFMKQALPPILTDKEKKRSVIGLSTNLLGDDLIDFCANTKVKFIRKHTQRLLMESEDSCFISHRMNNSRLFEGRPETLVDFPSTGIDTYRVLWNAYPEWRTLDEIFSCRETKSNTRKEKLAAIQILFQMGVLLVKNPK
The following text describes a protein:
Function:
May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Primarily found in the nucleus.
Sequence:
MGDKKSPSRPKRQAKPSADNGFWDCSVCTFKNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYAAPPPAKKERRERTDRDLPDDDHFDMDNSDSDRLSSLHPDSDHPERLGLEGGQLDRGHSLKERRQERVLDKPQALDTDRRPERAGLTPDLLQQQQPQPQQHPQQPQQPQQHSQQQPQQHPPQQHNRIDREHTDRAMLEKLQPLREHMEKDHPHTAGSGMQPAERMGAEREELKKGKIERAMMEKHKERHKSLTPSKKPTPKKMKPKLIQKSPAGESNGMKPGKSVTKNNKSVISRPKLKNVDRSSAQQLAITVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQHLSSSSESTDKGSSRASTPRRDHSSGHNETL
The following text describes a protein:
Function:
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
Subcellular Localization:
Cytoplasm.
Sequence:
MQVKENKQLCLISLGCSKNLVDSEVMLGKLYNYTLTNDAKSADVILINTCGFIESAKQESIQTILNAAKDKKEGAILIASGCLSERYKDEIKELIPEVDIFTGVGDYDKIDIMIAKKQNQFSEQVFLSEHYNARIITGSSVHAYVKISEGCNQKCSFCAIPSFKGKLQSRELDSILKEVENLALKGYTDMTFIAQDSSSFLYDKGQKDGLIQLIRAIDKQQALKSARILYLYPSSTTLELIGAIESSPIFQNYFDMPIQHISDSMLKKMRRNSSQAHHLKLLDAMKQVKESFIRSTIIVGHPEENESEFEELSAFLDEFQFDRLNIFAFSAEENTHAYSLEKVPKKTINARIKALNKIALKHQNHSFKALLNKPIKALVENKEGEYFYKARDLRWAPEVDGEILINDSELTTPLKPGHYTIAPSEFKDNILLAKVLSPF
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MEDENELMLELSIGGIFANPKPNPNVTESTKIDNRILKDGVRRRKREEKVKKMVDYGSCGSVSGPFVENKEWLEAQIVGQNDDEPACQKQKQEKFGSVDDEDKNLVFRPTACRSFRPYQGKNKLKLYCKMKSNGCSSDGQCSSHQGGASDDSQTNSSNSQLDQQAASTSTAIVEPSDQHQPAGSSKQTVLSTTKPNDRSNPHESSILTPPPKPEPPSSQHQQTSLLARMPCVSTTGNGPNGKTVSGFLYKYNTKKDVSIVCVCHGRSFSPAGFVEHAGGVDIAQPLKHITIYPAAFVS
The following text describes a protein:
Function:
Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm.
Sequence:
MEAAADLKDTASLTLKFEFNPKLGIDNPVLSLAEDHDPSELWSLERPRFCLLSKEKGRTFGFHLQQELGRAGHVVSMVEPGTSAQRQGLRAGDRILGVNNHVVEREDHAVVVRRIQASGPRVLLTVLAQHVHDVARAQQGDDACLCPTLGPGVRPRLCHIVKDEGGFGFSITQGHRGPFWLVLTTGGAAERAGVPPGARLLEVNGVSVEKFTHNQLRRKLRQSGEQVTLLVAGPEVEEKCRQLGMPLAAPLAEGWALPTKPRCLHIEKGPQGFGFLLREEKGLDGHLGQFLWEVDPGLPAEKAGMQAGDRLVAVAGESVEGLGHEETVSRIRAQGSCVFLTVVDPEADRFFSMVRLSPLLFLESTETSASPQDTCSASLVETKNPPVEDIAMPPDSCGSRQCFLYPGPGGGYGFRLSCVASGPCVFISQVTLGSSAARAGLQMGDVILEVNGFPLGGENDLERLQQLAEAEPPLCLKLAARSWQGLEAWNPQGLERTGL
The following text describes a protein:
Function:
Transcription activator required for the expression of genes involved in the catabolism of aromatic amino acids such as the aromatic aminotransferase II ARO9 and the phenylpyruvate decarboxylase ARO10.
Miscellaneous:
MISCELLANEOUS: Present with 319 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSAKKRPSGNAAFELPKRRRTYQACISCRSRKVKCDLGPVDNPHDPPCARCKRELKKCIFSSNKGTSNDLPPNSINAISLPSLGKSKQEIQNDSTSPILSDVPLSRKGISSEKSFKSEGMKWKLELSSMQNALEFLAQAAGTVAKEGAKEIIKEKSTTPKPLKSSLDATNKSATDEGLKRLSKSDSTNTLYENTADMLNHTLNTNRKTSQLMEEIGKVRPPPTRKIDDFDYIGPDSLLTKEEAIELIEAFFLTMHPFFPNIPLQLHDPKELAEYPILFCAILTVSARYHPFDTLGLDNGEDGMRHIEVHDKLWVYCQKLISQTIWAEASTRSIGTVLAFIIFTEWNPRSIHYKWSDYANDPELNNVNARGSKNISTRKDEEGLTGVGAIRRSDRMSWMLTGSAVRLAQDMGFIENSSKVFIVTHISETTSAMNMNQRSLLAESFSVLNLNLGKIENDGNESNEDYLGNEKFYLNEILPDEESKLRWKRVFENSENDHDNEKNFLTDWEREFLNDEYVLYYSNKKDDTNLAQNHIPPFPLRFSFAQRAKIEIIRILSIAYETIYCEKNKRKLATTDQRHNLSVLSVFSPLIEGWLSNYRELLVPLSDVPFSLADRKNKKQIFDNIDRINGESIITDFNYCQLYIFSLALQVDGKTSRLNMNEIVTSARYVELAYRSAKEILSSAKRVSRQGMLKYMPVRWVIRIIRSIAFIVKCYLTLTGSELATNPDARNILKLSAISVDETFDIIRDTAVTLKEATPDELHLCQRYAAILMYLCTEMKLRKKSYLERPPLLRDGTTPLESNRESSLEGQDLTKKPIFSKRIGYNKTETTFEPSERPLTEEINSNSQNSNDTSSKGIVDPFVEQNNDITTALLNNELFQGPSLSDEVTDWFGASEDIGLEFVEPWTELIEQRYMQCGDGDNNNFENLYNLFVNSNNINNDINNSRPITRK
The following text describes a protein:
Function:
Catalyzes the synthesis of 5,6-dihydrouridine (D) at position 2449 in 23S rRNA. Can use NADH as a source of reducing equivalents but not NADPH.
Sequence:
MERFDAIIIGAGAAGMFCSALAGQAGRRVLLIDNGKKPGRKILMSGGGRCNFTNLYVEPGAYLSQNPHFCKSALARFTQWDFIDLVNKHGIAWHEKTLGQLFCDDSAQQIVDMLVDECEKGNVTFRLRSEVLSVAKDETGFTLDLNGMTVGCEKLVIATGGLSMPGLGASPFGYKIAEQFGLNVLPTRAGLVPFTLHKPLLEELQVLAGVAVPSVITAENGTVFRENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFLNEQRNAHPNQSLKNTLAVHLPKRLVERLQQLGQIPDVSLKQLNVRDQQALISTLTDWRVQPNGTEGYRTAEVTLGGVDTNELSSRTMEARKVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQDLIAAKSS
The following text describes a protein:
Function:
Putative glutamine amidotransferase that represses shoot branching. May act as a factor that links nitrogen stress response and branching control. May activate strigolactones by amidation, or represent a new pathway for repression of shoot branching.
Sequence:
MVVANDLSSKILPRVLIVSRRTLRKNKYVDFVGEYHLDLIVSSGAVPVIVPRVNGIHSMLQSFEPIHGVLLCEGEDVDPSLYADDELSDLSPEDMEEIKKAHAEDMTIDREKDSIELTLARLCLERNIPFLGICRGSQILNVAAGGTLYQDIDKELGTTMTTTNHIDYDNYDGHRHEARIVEETPLHKLFEEMEIMVNSYHHQGVKRLAQRFVPMAYAPDGLIEGFYDPNRYDPKEGQFLMGLQFHPERMRLPGSDEFDYPGCALVYQEFVKAVIAFQKKQVNATQVEMKRKTTTLVKSFSQAEFLEANTVLSKQQENRLKQMGATVRNSCVYMKRMKMKEEQERAMDKLSAERLSDMLSFHHMMARLCSNAIKRKLLEPEHTDRTIESSFFLNY
The following text describes a protein:
Function:
Plays an important role in the regulation of tissue responsiveness to oxygen deprivation.
Miscellaneous:
MISCELLANEOUS: 'fau' is an acronym for 'fly, anoxia, up-regulated'.
Sequence:
MVYESGFTTRRTYSSRPVTTSYAVTTPRLDLCTDRPGSHRSRASSDYSYTSKSSVEKSSYDSSNPHSYRPERSTYTSTVEKTSRSGPGGSYNYSTERTSTTGAGPGGYSYSSTTSGNLPGGTKYRHFSYHV
The following text describes a protein:
Function:
Major keratinocyte cell envelope protein.
Miscellaneous:
MISCELLANEOUS: Transgenic mice expressing a C-terminal truncated form of loricrin exhibited, at birth, erythrokeratoderma with an epidermal barrier dysfunction. 4 days after birth, high-expressing transgenic animals showed a generalized scaling of the skin, as well as a constricting band encircling the tail and, by day 7, a thickening of the footpads. Transgenic mice also showed retention of nuclei in the stratum corneum. The mutant loricrin protein is found in the nucleus and cytoplasm of epidermal keratinocytes, but is not detect in the cornified cell envelope. The C-terminal domain of the mutant loricrin contains a nuclear localization signal.
Sequence:
MSHQKKQPTPCPPVGCGKTSGGGGGGGGGGGGGYYSGGGSGCGGGSSGGGSSCGGGGGGSYGGGSSCGGGGGSGGGVKYSGGGGGSSCGGGYSGGGGGSSCGGGYSGGGGGSSCGGGYSGGGGGSSCGGGSYSGGGSSCGGGGGSGGGVKYSGGGGGGGSSCGGGSSGGGGGGSSCGGGSGGGGSYCGGSSGGGSSGGCGGGSGGGKYSGGGGGSSCGGGYSGGGGSSGGSSCGGGYSGGGGSSCGGGGGYSGGGGSSCGGGSSGGGGGGSSQQYQCQSYGGGSSGGSSCGGRYSGGGGSSCGGGYSGGGGSSCGGGSSGGGSSCGGSGGGGYSGGGGGSCGGGSSGGGGGYYSSQQTSQTSCAPQQSYGGGSSGGGGSCGGGSSGGGGGGGCYSSGGGGSSGGCGGGYSGGGGGCGGGSSGGSGGGCGGGSSGGSGGGCGGGYSGGGGGGSSCGGGSSGGGSGGGKGVPVCHQTQQKQAPTWPCK
The following text describes a protein:
Function:
Proteolytically removes the C-terminal three residues of farnesylated proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MESLGVWMETVKEAPLFWGSLGLTTSIWLLDSLYLTGRERAACRRMSVPAPLAGRVSQEDFDSAREYRYESLSFSLLKSSSDFIVSTGLLIAGFMPFSWHLSGQVSEALGLPPATHPICHSIVFMTLTSLFDFVSDLPWRIYETFSLEARHGFNKQTPAFFLKDQIKMLGVNLALVSLLLSAFLKVIEWAGDNFFFYLWLTATASSVVLVLVYHDFIAPLFDTYTELPHGDLRTAIEALASSLKFPLTKLYLVHNSVRNSHSNAYFYGWGSNKRIVLFDTLLDAKLREQVTSETEGAVAEADDQAKAGGCSIPQIVAVLAHELGHWQHGHVYKTFLLQQLYFCGIFYLFQRLYGVDAIFEQFGFANERPTLIAMTIIFGYILSPLNTIWSIVLTAFTRRAEFEADAFAVKLGQGEALCEGLIKLSADNKSYPVHDWLYSAVHHSHPPILQRLAAIRSKKQQ