lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate.
Sequence:
MWYVSTRGIAPRVNFEGALFSGYAPDGGLFMPEELPQLDRETLCQWSTLSYPGLVKELCALFIGSELIPKDDLNDLIDRAFSRFRHREVVHLSRLRNGLNVLELWHGVTYAFKDLSLSCTAQFLQYFLEKREKHVTVVVGTSGDTGSAAIESVQGAKNVDIIVLLPKGHCTKIQELQMTTVLKENVHVFGVEGNSDELDEPIKTVFADVAFVKKHNLMSLNSINWSRVLVQMAHHFFAYFQCTPSLDTHPLPLVEVVVPTGAAGNLAAGYIAQKIGLPIRLVVVVNRNDIIHRTVQQGDFSLSEAVKSTLASAMDIQVPYNMERVFWLLSGCDSQVTRALMEQFERTQSVNLPKELHSKLSEVVTSESVSDEAITQTMGRCWDENQYLLCPHSAVAVNYHYQQMDRQEPSTPRCCLAPASAAKFPEAVLAAGLTPETPAEIVALEHKETRCTPMRRGDNWTLMLQDTIEDLSRRWRGHALNASQ
The following text describes a protein:
Function:
Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Note=Also located in intracellular compartments.
Sequence:
MASTVWGGAPWWGPPPPAPARPLTDIDFCSGAQLQELTQLIQELRVQESWSEGPKPGADLLRAKDFVFALLGLVHRQDPRFPPQAELLLLRGGIREGSLDLGHAPLGPYSRGPHYDAGFTLLVPVFSLDGTGPELLLDLESCSAWLRLPELMRGILVREAWQDCLGPPVPEESDMTHQTHSKESPTDRENSVDPSHDYVPEPEPHMSLQKSSSDLSESQSSYKDITNPETPEPLETLSSDALDADESQVPKPSEAPKAWPTLCPTQVTSWFFVKLAEVAESLIPVPGAPRLVHAARHAGVTTVLLATPEPPRHLLLFDLIPVVTVTGWPDTARSHSWAGPLVSESASFYLVPGSLPEQPSTSGWQLCFARQELALKERIPTPLLQAHAAAQALLRPLVAGTRAAAPYLLRTLLYWACERLPALYLARPENAGACCLGLLDELSRVLEAGALPHYFLSGRKLRVGDGSAALRGALAQLRGDPAQALREAVEEAKVARKGGGLAGVGGGTH
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDMDSAHLDSSLLTLAFRLIKAAQTAAPSVLADLLAEGAPAWFQDDDLGWSCLHYAAERKEPECLEVLLQGGAVWNAVDKWGRTAGEICLSLGDEEGWSIIRNEGIRSEMLHHALSGTSSPDATNNIVLRAEDKTSAGDNLVFLKSKLTWDVGKDGKERVLDADGNGVMMGWEEPLMVEHVKRLTEEHPKAELGAEGMSILNVGFGLGIVDRLFQECDPKPSHHTIIEAHPQVLEYIHKKGVHLLPNVRILQGRWQDWLLDGEKVGDVLSGTPDGMGFDAIFVDTFAEGYEDLKAFFEVIPDILNADNGRFSFWNGLGATNPTIYAVSSSLAELHLEDVGLQVEWHDVLIPESMREEVWKGVRRRYWDLPGYRLPIAKMSLI
The following text describes a protein:
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MEGPVLTLGLLAALAVCGSWGLNEEERLIRHLFQEKGYNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAKENRTYPVEWIIIDPEGFTENGEWEIVHRPARVNVDPRAPLDSPSRQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLPADSGEKTSVAISVLLAQSVFLLLISKRLPATSMAIPLIGKFLLFGMVLVTMVVVICVIVLNIHFRTPSTHVLSEGVKKLFLETLPELLHMSRPAEDGPSPGALVRRSSSLGYISKAEEYFLLKSRSDLMFEKQSERHGLARRLTTARRPPASSEQAQQELFNELKPAVDGANFIVNHMRDQNNYNEEKDSWNRVARTVDRLCLFVVTPVMVVGTAWIFLQGVYNQPPPQPFPGDPYSYNVQDKRFI
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEAHLRYHNGENPVTCGWCGRSFANIYNLKIHERIHTGERPHKCQVCSKTFSDPSSLSKHKLWHAGVKKKSCPVCRRMFATATQVRDHIRTHTKEKPFVCQQCGKSYGYKCDLTRHMREHNGNLFGPCPDCGRLFNHNGNYKAHLKTHLKKQNPLPVFFVEENEVIVTSQDRQVSPPSGENGKNLDTSMNNGSCVMSQEEEVMSATTSLEQNMLSHDDIVKNENSLVIVDQTMESNFET
The following text describes a protein:
Function:
Low affinity receptor for N-formyl-methionyl peptides. Receptor for lipoxin A4. May have an olfactory function associated with the identification of pathogens or of pathogenic states.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
METNYSIPLNGSDVVIYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIAVDVNLFGSVFLIAVIALDRCICVLHPVWAQNHRTVSLARNVVVGSWIFALILTLPLFLFLTTVRDARGDVHCRLSFVSWGNSVEERLNTAITFVTTRGIIRFIVSFSLPMSFVAICYGLITTKIHKKAFVNSSRPFRVLTGVVASFFICWFPFQLVALLGTVWLKEMQFSGSYKIIGRLVNPTSSLAFFNSCLNPILYVFMGQDFQERLIHSLSSRLQRALSEDSGHISDTRTNLASLPEDIEIKAI
The following text describes a protein:
Function:
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Miscellaneous:
MISCELLANEOUS: The 4 small acidic ribosomal P-proteins from yeast can be classified into two couples of similar but not identical sequences. Each couple (P1A/P1B and P2A/P2B) is distinctly related to one of the two acidic ribosomal P-proteins P1/P2 present in multicellular organisms; MISCELLANEOUS: Present with 602000 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MKYLAAYLLLVQGGNAAPSAADIKAVVESVGAEVDEARINELLSSLEGKGSLEEIIAEGQKKFATVPTGGASSAAAGAAGAAAGGDAAEEEKEEEAKEESDDDMGFGLFD
The following text describes a protein:
Function:
Could play a role in nuclear morphology, specifically nuclear size.
Subcellular Localization:
Nucleus membrane; Multi-pass membrane protein.
Domain:
The KASH domain, which contains a transmembrane domain, mediates the nuclear envelope targeting and is involved in the binding to the SUN proteins; The TIR domain mediates NAD(+) hydrolase (NADase) activity. Self-association of TIR domains is required for NADase activity.
Sequence:
MDEQVQEPLSDQVFINFRGDELREIFVNHLELQLRNAGINVFIDTKEQKGRRLQYLFTRIKKSKIALAIFSKRYCESKWCLDELVTMNEQMKEKKLVVIPIFYNVRSDDVKRAANPDGEGNLDGEFSLPFKQLKQNHAGEPERVEGWERALRSVTKRIGFSRSNSKYKHDTDFVLDIVKEVKKQLNIPTDNSWSAIGVAFLAITINLIFSFFIAPKYLPDQKFFQTPEWFIGTLAVVLASWFWYKNNQNKAPPPS
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
Miscellaneous:
MISCELLANEOUS: Present with 4490 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Sequence:
MGMLELVGEYWEQLKITVVPVVAAAEDDDNEQHEEKAAEGEEKEEENGDEDEDEDEDEDDDDDDDEDEEEEEEVTDQLEDLREHFKNTEEGKALVHHYEECAERVKIQQQQPGYADLEHKEDCVEEFFHLQHYLDTATAPRLFDKLK
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MIYSTSVMSMMKLLEMEESLKTNLDIYVQEMQSKLDLIKLYQDSLKRVTLTTLEEKEEYVSNPLNAFPMLRRLNQDWPKWLRYIKLAIASKKIKEMEVQLKSAPIDDDLKVALKGMTRIEKFHNLHAEDLTKGVLMGKKLNSHLTAPDCVALGDYYYNQTQFSGSTHWYRMALRVHTHPRGMIYAKVLGLKRKRIYKKYAKALLKESLNSDKSKPTPTEKSEWNRLAKEVTREDNYDNVKKLIDEYLSGDEKIFQEVAARLKRKPTKLERGCRGEWPKKSSPELICRYNRDTSAFLKLAPLKLEFLSVQPMILLYHDVLYENEFKSMRDIAMYNGSMIDGWTYVDFDKKGNPKQQDRVVKMIAFQGTTAPFTLSINRRMADMSGLEMRDNMVLYLTNYGLGGHFGKHVDYVELAKRPPDFFADFGGDRIATALIYASDIPLGGTTVFTKLKIAVQPKKGSALIWFNLNHAGEPDPLTEHSVCPVVLGSRWIISKWIHERQQVFKKPCLA
The following text describes a protein:
Function:
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Subcellular Localization:
Endosome.
Sequence:
MQDLDTPKEVPQAIRQANTDEEANIENGNESQQQQQREQQQQEPENHTNEIITNSNNSTDSTFSDTEDDYMLSDDEELNRILSRETSNHHHHGLPSSGSMVDHAQFFAEALSHALDSIDIDRSLVLQAQISGKLNNENQKIIEKKEILIEKLKNIQLMYGKNFGLLADGKESRVDKMKKDISFIENRITKLMHGGSETKSSIPFFKNKSNMGVEQKYPIEFNQAKDKVIERQIDDDDDNEEIDF
The following text describes a protein:
Function:
During centriole duplication, plays a role in the centriole elongation by promoting the recruitment of the microtubule-binding elongation machinery through its interaction with RTTN, leading to the centriole to centrosome conversion (By similarity). In addition may play a role in the primary cilia assembly (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Recruited to the nascent daughter centriole early in the duplication cycle and localizes to the proximal centriolar lumen just above the cartwheel. Co-localizes with RTTN at the centriole.
Sequence:
MMVYNGSQLESVEEGEAVAVPGPPPEPRAPEPGAPVPEPGLDLSLSPRSESPGRGRPNCSPGRRKGRADRRGGARKGRQVRFLLAPPSPVRSGPPPAAASSSEKPEAPQDLGTPVQQSSLALSLELQAARAAAGGQFDAAKAVEEQLRKSFQTRCGLEESVTEGLNVPRSKRLFRDLVSLQVPEEQVLNAALREKLALLPPQARAPPPKEPPGPGPDMTILCDPETLFYESPHLTLEGLPPLRLQLRPRPSEDTFLMHRTLRRWEA
The following text describes a protein:
Function:
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MTTNNSNDNNKRYGIIKQQLQQQQQQHHQQHEQHSRLVEMTAGCGAGFMASLFTTPLDVIKTTLQVDNSSNKTIMSTVKSILDRKGGVKNLYLGLKPTLVGQIPSWAVYFSTYTFCKELFTKENDKHSLLEKESPLIFMTSAIIAGAATSICTSPIWLIKTRFITQEMVGRQKKYRGIVHSMVSIYHEEGFRGLYKGLGPSLLGVLHVGVQFPLYEKFKSILKEKNKNKELGIVEIMIASSVSKIIASVVAYPHEVLRARSQDSSPDSPNRTYRGNIIQMFKQIVREEGWRGLYRGMGVNLLRVTPSCVITFTSYEYIKKFLSQNQNHF
The following text describes a protein:
Function:
Probable NADH oxidoreductase (By similarity). Mitochondrial effector of cell death that plays roles in developmentally regulated cell death and normal mitochondrial function.
Subcellular Localization:
Mitochondrion intermembrane space.
Sequence:
MSIWGVRCLTQRFIRQAYILANRRLLGPVPQRSPPAYAPLRPAHSSLYQMVKKRTLEARTKLQANKYPNHQVCVTKPSTTPPVEEYETAVEGAGVPAYANAQFQAHSQSEPLFKVGFADVKSVCSAKDVLKSDSAKLSTSQPVLDSCKATSPCEEFKRKRKETTCQPCDEDGTAPGGGDGGDEECECRMKDLRLKCLLGALAALLAGGFLAWFMTRDTDDSEAKKAEAEEEERKRRLVAGLATSPPSSEDLPKHVPYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELWYTPNPNEDPIKDYRFKQWTGSERSLFFEPDEFFIDPEDLDDNANGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMLRDAPPSVLEKVMVYRTPDDFDRLRKLAAEKRSITIVGNGFIGSELACSLAHYSRENNGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNASIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSLGGFVVNAELEARRNLYVAGDASCFFDPLLGRRRVEHHDHSVVSGRLAGENMTGAKKPYQHQSMFWSDLGPEIGYEGIGLVDSSLPTVGVFALPSESATRVDQLSESSDSDVPETSTSSSQSSKSDAGASQDGVTCDPDEAGNYGKGVIFYLKNDKIVGILLWNLFNRIGLARTIINQNKKYDDLNEVAKLFEIHA
The following text describes a protein:
Function:
Endoglycosidase with broad specificity that cleaves the chitobiose core of high mannose and complex N-linked glycans. Is able to release N-glycans from diverse host glycoproteins such as human and bovine lactoferrin, immunoglobulins A and G, and ribonuclease B. Is active directly on human breast milk - a complex matrix of lipids, oligosaccharides, and proteins with disparate glycosylation types - successfully removing a significant proportion of the total amount of N-glycans. Does not recognize O-linked glycans or free human milk oligosaccharides (HMO).
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MTFIKQMMPRYVASMTAGIVAAAMAATCAFAPVANADAVSPTQETIQSTGRHFMVYYRAWRDVTMKGVNTDLPDDNWISMYDIPYGVDVVNIFSYVPSGQEEQAQPFYDKLKSDYAPYLHSRGIKLVRGIDYTGVAVNGFRTFMKEQNKTESEATEADYDAYAKQVIDKYMISVGLDGLDIDMEAHPNDADVKISDNVIRALSKHIGPKSAKPDTTMFLYDTNGSYLNPFKNVAECFDYVAYQQYGSSSDRTARAAADYQPYIGNEFVPGLTFPEEGDMNNRWYDATEPYEESHFYQVASYVREHNLGGMFVYALDRDGRNYDEDLRRIVPSNLLWTKTAIAESEGMALDTAKTAANHYLDRMSLRQVIDDNAASADKARDMVGKAANLYETNKAVLGGDYGEGFSNTYDPTLEAGLLGIDISVLQQQIDKSSEIIGADTAESDAKTALRMARDAAIDGLTGKIYTADQVSAWSQALKAALDATVPVPTPDSTDQNGNRDKVTNHKVQGQPKQLSATGISTDIIVAVGVTLAIAGVALSLSRKLS
The following text describes a protein:
Function:
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MATLRRLREAPRHLLVCEKSNFGNHKSRHRHLVQTHYYNYRVSFLIPECGILSEELKNLVMNTGPYYFVKNLPLHELITPEFISTFIKKGSCYALTYNTHIDEDNTVALLPNGKLILSLDKDTYEETGLQGHPSQFSGRKIMKFIVSIDLMELSLNLDSKKYERISWSFKEKKPLKFDFLLAWHKTGSEESTMMSYFSKYQIQEHQPKVALSTLRDLQCPVLQSSELEGTPEVSCRALELFDWLGAVFSNVDLNNEPNNFISTYCCPEPSTVVAKAYLCTITGFILPEKICLLLEHLCHYFDEPKLAPWVTLSVQGFADSPVSWEKNEHGFRKGGEHLYNFVIFNNQDYWLQMAVGANDHCPP
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MAADECFQQFGGMRWNCSLLSRGNKSSFMTLPDYLPDGCKEASILKAFFSASMTFNVARACKDGQLPQCGCSRREKPRHLPAEWVWGGCGDNTEYGFKFGVGFVDSREREMNYPRYSHELKIMLSNLHNNMVGRRTVVGLSKASCRCHGASGSCSMKTCWHQMADFNEIARELKFKYENLPHLVKFNNAGTNSDYENIDNDDNTQQQPATDTSSNRPTRDTLIYTEPSPDFCEALTNTSWPGTHGRQCKRGEPGSEGCDLMCCGRGYNTFREKVTERCRCHFVWCCSVHCSTCEKYIDVHVCK
The following text describes a protein:
Function:
May play a role in spermatozoa mobility.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDTDEQGAPGRKPLDRPQTPDELKFYARNYVMLALLAMILFLPFGILAIYFSIQTNEANKCSNWEDAYRNSSRTMWFNMLAIVAFVGIIYILVLVL
The following text describes a protein:
Function:
Calcium-regulated non-lysosomal thiol-protease.
Subcellular Localization:
Nucleus.
Sequence:
MDAAALERDAVQFARLAVQRDHEGRYSGAVFYYKEAAQALIYAEMAGSSLEHIQEKINEYLERVQALHSAVQSKSADPLKSKHQLDLERAHLLVTQAFDEDEKGNVEDAIELYTEAVDLCLKTSYETADKTLQNKLKQLARQALDRAEALSEPLTKPLCKVKATNIKPKPPPTRTHFPLGTNPFQEGPQPFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMNIDLRERFAYPMPFCDRCGKLPLSPKQKAMFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFTKKLITSIIYPQNKDGESEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYQRFHKGDVLITASTGVMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTPQKIDNGIFWISWDDLCQYYDVIYLSWNPGLLKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTVSKQINGKWSGQSAGGCGNFQETHKNNPIYQFHIEKSGPLLIELRGPRQYSVGFEVVTVSVVGDPGPHGFQRKSSGDYRCGFCYLELESIPAGIYNIIPSTFLPKQEGPFFLDFNSVIPIKTTQLQ
The following text describes a protein:
Function:
May positively regulate ERK1/2 signaling and AKT1 activation leading to HIF1A up-regulation with an increased expression of glycolysis genes and enhanced glycolysis.
Sequence:
MAAPVTRQVSGCAGRVPSPAGSVTERGQPLAAAVAELPVLDASGRRVTFGALFRERRAVVVFVRHFLCYVCKEYVEDLAKIPKSVLREADVTLIVIGQSSYHHIEPFCKLTGYSHEIYVDPEREIYKRLGMKRGEEISSSGQSPHIKSNLLSGSLQSLWRAVTGPLFDFQGDPAQQGGTLILGPGNNIHFVHRDRNRLDHKPINSVLQLVGVQPVNFMSRPTVIHV
The following text describes a protein:
Function:
Involved in chitin biosynthesis.
Sequence:
MPASTSIPETPSKLPDALLVNSDPASKVDNVSVKIEQESPLALEGSPLPTVSDVLPETNNAHEEVSSSSWSLSSSDSIMSYDSLSDDVSVLSFLDCPLTTFETAPSIASFSNSAADVSSHSRSSSSWSAKLSRFTKHASKPSLSSNSSDSSFSKSGSESNALSSRGSFELEPHGIHRHVSRAKRLLSKFYSKFHHKKEDSSFDPLAPLVFAPNTSRVLRVTNEANASAISLEKATSLSSQEQPGSEIKKELSLYDHEFDQILDLAIKAKKDGNLENAIEFLEYIMPEVASQQNFVPYELAELYKQRGTSQDLKSILPLYMLAASLGHDRSSFLVGEAFFYGTYGARENKLRALQYYHLANDKGNADAMLALCKLYLRGLPGHIFPSSRRAFEYAHRAAMLGHAPACYVLGKFYETGVGCVKDLAKSEAGFRAGLINDSPITDADALQIASTLVLLQ
The following text describes a protein:
Function:
Transcriptional repressor that binds NRG1 response elements (NRE) of target promoters. Involved in regulation of chlamydospore formation, hyphal growth, virulence, and stress response. Plays a key role in regulating true hyphal growth, but does not regulate pseudohyphal growth in the same fashion. Directs transcriptional repression of a subset of filament-specific genes such as HWP1, HYR1, ALS8, HWP1, or ECE1; via the TUP1 pathway. Functions with UME6 in a negative feedback loop to control the level and duration of filament-specific gene expression in response to inducing conditions. Plays a key role in biofilm formation and dispersion. Also plays the role of a negative regulator of virulence in mice models. Required for the expression of the cell wall genes RBR1.
Subcellular Localization:
Nucleus.
Sequence:
MLYQQSYPITNKLLNASAAGSTSTASIIDGGCTLSKPGSGKTKSTTSLPSFNELLTSIPLPNEFKPSTKNTNQAAAATATSPYNYYMGPPAQHRLPTPPPYPMSSPTTATAATPLSQQSPHLQPQQTLQQPQPYHQQYYNYQYAAPPYPHPSQVPPPASYQQRHQQPMYQNTNGVPIIIRPSPGLITPTSTTFDHAKIRSNSTGDLSANSLALSSNNNTQSKDPRRKHVCKVCSRSFTTSGHLARHNRIHTGERKHQCPWPTCEARFARQDNCNQHYKTHTNGKNKRNRQQHRTLEASHVGTKYNTKSLV
The following text describes a protein:
Function:
Involved in the degradation of the monoterpenes beta-myrcene and limonene. During anaerobic degradation of beta-myrcene, catalyzes the NAD(+)-dependent oxidation of geraniol to geranial. Can also catalyze the oxidation of (S)-perillyl alcohol to perillyl aldehyde, and to a lesser extent, the oxidation of nerol, citronellol, cumic alcohol, and benzyl alcohol. Cannot use NADP(+) instead of NAD(+) as cosubstrate.
Sequence:
MNDTQDFISAQAAVLRQVGGPLAVEPVRISMPKGDEVLIRIAGVGVCHTDLVCRDGFPVPLPIVLGHEGSGTVEAVGEQVRTLKPGDRVVLSFNSCGHCGNCHDGHPSNCLQMLPLNFGGAQRVDGGQVLDGAGHPVQSMFFGQSSFGTHAVAREINAVKVGDDLPLELLGPLGCGIQTGAGAAINSLGIGPGQSLAIFGGGGVGLSALLGARAVGADRVVVIEPNAARRALALELGASHALDPHAEGDLVAAIKAATGGGATHSLDTTGLPPVIGSAIACTLPGGTVGMVGLPAPDAPVPATLLDLLSKSVTLRPITEGDADPQRFIPRMLDFHRAGKFPFDRLITRYRFDQINEALHATEKGEAIKPVLVF
The following text describes a protein:
Function:
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEQMSGELHAASLLYMRRLMKCLGMLPFGQNLFSKGFCYVLLFVSLGFSSYWRFSFDYEFDYDFLNDRFSSTIDLSNFVALVLGHAIIVLELLWGNCSKDVDRQLQAIHSQIKLQLGTSNSTDRVRRYCNWIYGSLIIRWLIFIVVTIYSNRALTINATYSELVFLARFSEFTLYCAVILFIYQELIVGGSNVLDELYRTRYEMWSIRRLSLQKLAKLQAIHNSLWQAIRCLECYFQLSLITLLMKFFIDTSALPYWLYLSRVEHTRVAVQHYVATVECIKLLEIVVPCYLCTRCDAMQRKFLSMFYTVTTDRRSSQLNAALRSLNLQLSQEKYKFSAGGMVDINTEMLGKFFFGMISYIVICIQFSINFRAKKMSNEQMSQNITSTSAPI
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein.
Sequence:
MVVTSDTLIWLGQVKCSGNCGYISRKIQVADKQVNDSEPTTLAIAFDTMVNSENMLIVLGVIGNVTSFFVFASLLPTIWRIWKNKSVDEFKYHPLAVGIIHSIMWVFYSMPFVHPHSIPVTTVNSVGLVMYIIFNIIYYVNTNKTTRRSMVLHYIAEFVFLAGLVWSTLVTFDSHATRSGYVGFFCVFFGIILYGLDLGITVKAIRAKNVKSRLLLYSLVCFLNGLVWSVYALVKYDPYILIENSLGALIGCIQFLLYIGYYCVERFRTIKLSPVDDC
The following text describes a protein:
Function:
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.
Subcellular Localization:
Cytoplasm.
Sequence:
MVTITRFVPPEKFDLILLALELEFVKKGTKNEQVDAVVLSTQLKKKFMYQVFTVGQRVTFEFHGTNYILTVNRAVIEADGSQTNGIERGMIFNDTYFVFEASNASGIKIMNQREAATRKIFKEKEFFNNLSLEIGGLNAVFVDLFRRAFSYRILPPYLRDRLGRKQVKGVLLYGPPGTGKTLMARQIGKMLNGKEPKIVNGPEVLNKFVGETEKNIRDLFADAENDQRTHGDDSELHVIIFDEIDAICKSRGSSSDGTGVHDSIVNQLLTKIDGVEALNNVLLIGMTNRKDMLDEALLRSGRLEVHIEIGLPDEAGRVQILHIHTKMLKENSFLAPDVNLQELAAQTKNYSGAELEGVVKSATSYALFRHLNMEDLSNPVDEENIKITMEDFRQGLREVMPAFGASPKALQNCRPKGFVDCGDRQNLIYKRIMFLVEQVSNETSPPVTCLLKGPSGSGKTALAATIGIDSNFPYVKIVSAETMAGLQESTKAARIAKVFEDAYKSPLSIVILDNIERLLEYSEIGPRFSNMILQTLLIYLNQLPKEGSKLLVLGTTSELTFLKAVGLRKAFSVTYDVPLLRTEDAKKVLKQLNVFSDDDMEEASKALNDIPIKKLYFLIEMAAQRDGRSKETIYTRKEKLDLAHFFDCLEEVTEN
The following text describes a protein:
Function:
Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
Subcellular Localization:
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Sequence:
MNHSNTTNTDRDAYLQLGKSLNEQHSNQLSTQLQVFQSALINFANDHGDEISSNLEFKNKFTQIVQSIGIDPLDLLLYTSQNDRNGGTSNSNSSSNSSSNYKRSNVVATNFGVALAVKIIEICQQTRDLNGGLISLKELISTLQNSCETEGISLVVSEKDIESSLNNLNTLGKGYEILIINGKKWLKFSSTENLSNDQLKIYELCEFMGGYVTYRLLRDNYGWDKVRCKTVIDEMIMNGFLWVDSQDNGEWQYWEPSWISN
The following text describes a protein:
Function:
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.
Subcellular Localization:
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus.
Sequence:
MSLTTRDDVRNRLRPFGVIFESTLTDLIKGIRAAKDLPAKERFLKQAVSDCHQEARNQDLTVKTLAILKLAYLEMLGYDMSWASFHVLEVMSSPKFQQKRVGYLAAIQSYRDDDDVLMLATNLLKRDLTSSSPVEVSVSLSAIATIVTPSLAQDVHPEIVKMLSHSKPYIRKKAVLAMYKIFLQYPEALRTSFSRLRDRLDDSDPSVVSATVNVICELAKKHSKNYVPLAPQLYQLLTTSSNNWMMIKILKLFSSLAPIEPRLKPKLLPQIMTLIQSTSALSLQYECINCIVSGGMLGEDDHDVAGVCVEKLSSFVNQGDQNLKYVGLLALGKIVKVHPILVGKLQGVILECLKENADSTIRERALELANDLASEHNVETIVNLLLSQQLTHASISYILDMCCRDTYSLISDFEWFLNVLKKLALVDFPLEDPARIGETLRDLCMRVPDMREEITGVCYEIFTDGGVYLRNPGVLPPVLFCLSEYPMHRQKDILDFCLNSYSHVRENSGSSNNAVDLAVCVCIVKVFGKFCEGIIWSSPNELYVKKTVTNVIKFLSSYLASPDYELQDFATQFSELFKVISESLEEEGVPVLLTEVLPSFFAYELNPVAPDTQKRIPFLDLELPPELEQTLEVEFSDIEDEEVYVEEEFTPQFASTVSGVQKESLLDARKERLEKQKDDPFYISRDTTPNPLKDEQVDVDSIPVVDLQINETSIKTPPIQTKPKRKIKIIKDEQIDGEIVPKLEVTKNVKKNVLIRPNQLDQFELEDDKDSPEVAQMKQELKDKKDKKDKKDKRDKKDKEKKPKSKAKKEGADGEVKEKKRKKRVAVIE
The following text describes a protein:
Function:
Has antibacterial activity against the Gram-positive bacterium M.luteus with an IC(90) of 125ug/ml. Has weak antibacterial activity against the Gram-negative bacterium A.hydrophila.
Subcellular Localization:
Secreted.
Sequence:
MRSSLLLGLTVVVLLGVIVPPCMAGQALNKLMPKIVSAIIYMVGQPNAGVTFLGHQCLVESTRQPDGFYTAKMSCASWTHDNPIVGEGRSRVELEALKGSITNFVQTASNYKKFTIDEVEDWIASY
The following text describes a protein:
Function:
Involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, GP1c and GT3 from GD1a, GT1b, GM1b and GD3 respectively.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MRYADPSANRDLLGNRTLLFIFICAFALVTLLQQILYGRNYIKRYFEFYEGPFEYNSTRCLELRHEILEVKVLSMVKQSELFDRWKSLQMCKWAMNISEANQFKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIYHINQEIFRMFPKDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITERFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGLYITHHYYDNVKPRPGFHAMPSEIFNFLHLHSRGILRVHTGTCSCC