lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
Subcellular Localization:
Cytoplasm.
Sequence:
MISSHPEIELAGFIEQTCLKPTATADDVRQMCWEAQRYRFAAVCVAPVYAPLAVELLHKQKPQVFTVVGFPLGLATAPCKLFEAQEAAARGVTGLEVMVNLGAIKSGHYNAIYEELGQIVDAVGCEVRAILELNLLDATERRHVAEVCLDVGVTALKTSAGWSGPVRPEDILGLRRILRNQLGIKVAGGIHTLNQALELLAAGANRLGTGRGVEILREQHALGKTA
The following text describes a protein:
Function:
Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.
Subcellular Localization:
Nucleus.
Sequence:
MDEAAGDLKQALPNTCDNVQIHVEVHQKSNSTAKKEDIRMSVLKLLNRHNIVFGDYKWTEFDDGFLNSNVQSVSIVDTELKLKERQPIDLSKSSLTIHIFHLNEEGPSIENLEEENEDIVAANHWVLPAAEFHGLWESLIYDTEVKSHLLDYVTTTLLFSDRNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSYRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQELIDDKDALVFVLIDEVESLTAARSAFKAGTEPSDAIRVVNAVLMQIDQIKRYPNVVILTTSNITEKIDMAFVDRADIKQYIGPPSAAAIFRIYLSCLEELMKCQIIYPRQHLLSLRELEMIGFVENNVSRLSLVLKEISRSEGLSGRVLRKLPFLAHALYIQSPSVTMTAFLQALSLVVDKQFEERKKLADCV
The following text describes a protein:
Function:
Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
Subcellular Localization:
Cytoplasm.
Sequence:
MKEKSRQKRILEIKKKLLQQKQQILIDAGIMLSNLPSESNLSEIGDIASQEIDRSFLLRLRDRERKLLKKIEKTLEKINNGTYGICEACGAEIPIERLEARPVTDLCIECKTEQEEAEKLKES
The following text describes a protein:
Function:
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MMQTVAVIDYGMGNLHSVAKALEHVGAGRVLVSSDAAVIREADRVVFPGVGAIRDCMAEIRRLGFDALVREVSQDRPFLGICVGMQALLERSEENDGVDCIGLFPGQVRFFGKDLHEAGEHLKVPHMGWNQVSQAVEHPLWHEIPDQARFYFVHSYYIEAGNPRQVVGHGHYGVDFAAALAEGSRFAVQFHPEKSHTHGLQLLQNFVAWDGRW
The following text describes a protein:
Function:
Required for arbuscular mycorrhiza (AM) development during AM symbiosis with AM fungi (e.g. Glomeromycota intraradices).
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MEPNNVFSLLLIISLWFLLTFHSNAETSTYIIHMNKSFFPQVFTTHHDWFKSTIHSLKSKTLVPDDYDQASKQSQKKLVYTYDHAMYGFSAVLSSNELEILKNIDGFVSAYQDRTATIDTTHTFEFLSLDSPSGLWHTSDFGDDVVVGVIDTGLWPESQSFKDDGMTKKIPNKWKGTCETGQEFNTSMCNFKLIGARYFNKGVIASNPNVTISMNSARDTIGHGTHTSSTVAGNYVNGASYFGYAKGIARGIAPKARIAMYKVIWEEGRFASDVLAGMDQAINDGVDVISISMGFDDVPLYEDPIAIASFAAMEKGIVVSSSAGNAGPEFGTLHNGIPWLLTAAAGTIDRTFGTLVLGNGQSIIGWTLFPANAIVENVLLVYNNTLSSCNSLNLLSQLNKKVIILCDDSLSNRNKTSVFNQINVVTEANLLGAVFVSDSPQLIDLGRIYTPSIVIKPKDAQSVINYAKSNNNPTSSIKFQQTFVGTKPAPAAAYYSSRGPSHSYPWILKPDIMAPGSRVLAAYIPNKPTARIGTNVFLSSDYNFMSGTSMSCPHVSGVAALLKAAHPQWSAAAIRSALITTANPLDNTQNPIRDNGYPSQHASPLAIGAGEIDPNRAMNPGLIYDATPQDYVNLLCGLKFTKNQILTITRSNSYDCENPSLDLNYPSFIAFYSNKTRSMVHKFKRIVTNVGDGAATYRAKVTYPKGSVVTVSPDILTFKYKNEKQSYNIIIKYVMYKKENVSFGDLVWIEDGGAHIVRSPIVVAPTGIV
The following text describes a protein:
Function:
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
Sequence:
MSEEPPHCNHFVIRKKRFCRMTVKPGDTFCGEHQPAGATTDDKIRIVCPLDPKHTCYAHNLRKHLKICNARPGAPVPYLQPGVNSGGAPEDHKLLSEFAPSDIVAVIGKINTIFEDCLRGKITSKLGGHKVVEAEMAKPEYGDKSKKHLKQASAILGLLDESGLIKPETCFVEFGAGRGLLSYWLAQACPQATFLLIERSSPKHKRDNKLEKSDKVRRIRADIADLVLDKLDAVSGNPIVGVTKHLCGDATDLALRCLANVSSVKVGGLTMTFCCHHRCRWPSYVGKDFFNRFGLTKNDFEMMCGMSSWATCGTGFSREKNQTGGTVEGNDRDKEIGVTRSQKEELGRRSKAILNWGRLQFLEGLGFECRLHYYVEADVSLENVCIVAKK
The following text describes a protein:
Function:
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MPKEFSRTQRVAQQLQKELAMILQREVRDSRLGMVTISDVEVSRDLAYAKVFVTFLCIGEQTPESCLAALREHEVQIRMMLGKQIRLRLTPEIRFYYDNTLVEGMRMSNLVTEVINSDKRRKHEAGRDEDEA
The following text describes a protein:
Function:
Plays a role in cuticle biogenesis. In complex with doxa-1 and the dual oxidase bli-3, promotes the generation of reactive oxygen species (ROS) and tyrosine cross-linking of collagen, thus stabilizing cuticular extracellular matrix.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MGALGDSAYGARGRLIKFSYIVTALISILFSISCICYGIWLLARRSQYAELVSPSLYVDVGRILVIISILSILNYLICFYAIFKEMRCFVTSCAVASIVIAVMLIIGGCIGLNFRDQLTHYTPLNLKMLTSLRELYGTHDMKGITESWDALQSNFKCCGVNGTDNAQIWKTSKWYMHQRAPKLLIPESCCIPSEIERCRSNPFDQDAPPPYYTSTCYEPLQNDLLHVMNVASWLCITNAIVQIIPSVAGCWYSKLIRK
The following text describes a protein:
Function:
G-protein coupled receptor which selectively activates G proteins via ultraviolet A (UVA) light-mediated activation in the skin. Binds both 11-cis retinal and all-trans retinal (By similarity). Regulates melanogenesis in melanocytes via inhibition of alpha-MSH-induced MC1R-mediated cAMP signaling, modulation of calcium flux, regulation of CAMK2 phosphorylation, and subsequently phosphorylation of CREB, p38, ERK and MITF in response to blue light (By similarity). Plays a role in melanocyte survival through regulation of intracellular calcium levels and subsequent BCL2/RAF1 signaling (By similarity). Additionally regulates apoptosis via cytochrome c release and subsequent activation of the caspase cascade (By similarity). Required for TYR and DCT blue light-induced complex formation in melanocytes (By similarity). Involved in keratinocyte differentiation in response to blue-light (By similarity). Required for the UVA-mediated induction of calcium and mitogen-activated protein kinase signaling resulting in the expression of MMP1, MMP2, MMP3, MMP9 and TIMP1 in dermal fibroblasts (By similarity). Plays a role in light-mediated glucose uptake, mitochondrial respiration and fatty acid metabolism in brown adipocyte tissues. May be involved in photorelaxation of airway smooth muscle cells, via blue-light dependent GPCR signaling pathways.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cytoplasm.
Sequence:
MYSGNRSGDQGYWEDGAGAEGAAPAGTRSPAPLFSPTAYERLALLLGCLALLGVGGNLLVLLLYSKFPRLRTPTHLFLVNLSLGDLLVSLFGVTFTFASCLRNGWVWDAVGCAWDGFSGSLFGFVSITTLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRYILDIHGLGCTVDWRSKDANDSSFVLFLFLGCLVVPVGIIAHCYGHILYSVRMLRCVEDLQTIQVIKMLRYEKKVAKMCFLMAFVFLTCWMPYIVTRFLVVNGYGHLVTPTVSIVSYLFAKSSTVYNPVIYIFMNRKFRRSLLQLLCFRLLRCQRPAKNLPAAESEMHIRPIVMSQKDGDRPKKKVTFNSSSIIFIITSDESLSVEDSDRSSASKVDVIQVRPL
The following text describes a protein:
Function:
Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).
Subcellular Localization:
Cytoplasm. Mitochondrion intermembrane space.
Sequence:
MPGLAAASPAPPEAQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALGFKI
The following text describes a protein:
Function:
Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.
Sequence:
MLSRSISRLVRPVRLDLPPWAGPRIGCVRSSSLISFAGRSISSSSASWAKKKAGGNSTAKPSPEGLAKIPSTNLNQDGNEERFNRNKVEKEMDMTVARLRQNVNLIVNRVGRLTPAYLDGIKLLHDHQRLGINSVAQVIVVDSNTLSVVPYDPSYTKSIEQALYGSTLNLAPKLQPDGSLSIAIPRLTIDTRKVLAKESGELCEQARAGIRNIRQAAQKASRNDLDSNLITKDDFKDNQKSLDNVSKTYGKLVDGIESKSKAVLLDK
The following text describes a protein:
Function:
Involved in the biosynthesis of the parasiticide antibiotic grixazone. Catalyzes the oxidation of 3-amino-4-hydroxybenzoate (3,4-AHBOA) to yield the corresponding quinone imine which is then non-enzymatically conjugated with the thiol group of N-acetylcysteine. The resultant compound is oxidized to its quinone imine enzymatically and is then dimerized non-enzymatically with another quinone imine oxidized by GriF to yield grixazone B. 3-amino-4-hydroxybenzaldehyde (3,4-AHBAL) can also be used as substrate to yield grixazone A. In the grixazone biosynthetic pathway, it can also function as an o-aminophenol oxidase that catalyzes the formation of the phenoxazinone chromophore from alpha-aminophenol. It can also use 2-amino-4-methylphenol, and to a lesser extent, 3,4-dihydroxybenzaldehyde, catechol and 3,4-dihydroxy-L-phenylalanine (L-DOPA) as substrates. In contrast to tyrosinases, it does not display monophenolase activity.
Sequence:
MVHVRKNHLTMTAEEKRRFVHAVLEIKRRGIYDRFVKLHIQINSTDYLDKETGKRLGHVNPGFLPWHRQYLLKFEQALQKVDPRVTLPYWDWTTDHGENSPLWSDTFMGGNGRPGDRRVMTGPFARRNGWKLNISVIPEGPEDPALNGNYTHDDRDYLVRDFGTLTPDLPTPQELEQTLDLTVYDCPPWNHTSGGTPPYESFRNHLEGYTKFAWEPRLGKLHGAAHVWTGGHMMYIGSPNDPVFFLNHCMIDRCWALWQARHPDVPHYLPTVPTQDVPDLNTPLGPWHTKTPADLLDHTRFYTYDQ
The following text describes a protein:
Function:
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MEVGVLSMRYAKAMIEYAQEKGVEDRLYNEFFTLSHSFRVQPGLREVLDNPVVSVKDKLALICTAADGNGESSREFVRFITLVLRNRREGYLQFISLMYLDLYRKLKHIGVGKLITAVPVDKETENRIRSAAAHILHAQMELDTVIDPSIEGGFIFDINDYRLDASIATQLKRVKQQFIDKNRRIV
The following text describes a protein:
Function:
Protein mannosyltransferase (PMT) involved in hyphal morphogenesis and drug sensitivity. Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. PMT1, PMT2 and PMT4 account for most of the protein-O-glycosylation activity, while PMT5 and PMT6 may specifically modulate a much narrower spectrum of target proteins. Required for biofilm formation.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTKELPSGYFQGPFRPYKTFQPSLTERPLSKFEQFAVFSILLISLIRLYKLYIPDRVVFDEIHLIKYIKNYYDGSIFVDIHPPLGKLIYFYITKLFSFDKDFQIDIIGDLYPEDFPYLWLRLFSGICGIGHVLLTFFTLRITCNSVISIVITILICLENSMVTVSRLILLEGPSLFVQSLVIYNYKAFTTRIPFTGCWYFNLFVTGIALGLNISLKISGLFTFAWVGILTCVQLWEILGDLRISIWQFIKHLVLRVVAFIMVPLTIYCSVFYIHFENLPNEGPGSGFLTPHFRSTLDDYQQQPLQVLYGSTITIKHNALEKYLHSHDLTYPRGSNLQQVTLYDFPDVNNEWVIETKQKYNEEKLMTDQREVKDGDVVRLYHKATGHYLHVNDIRPPISEHEYSYEVNGNETRGLLGNEDYEFKIRMLVKKPHAENDLPLIKLRTTETIFQLIHQATRCNLMSHEQKLPDWGEYQNEVLCVKEPTIPNTLWYVESSSHPLLKDTKKLKTFPKFSFWSKLIETHKVMFNLNKGFTNPHPYASKPLDWPLLSRGIAFFSNYNLKSIDEESSLIYYLGNVAIYYSVFFVGLIAIFKCAIYSFIKLNPYASPPSSSKSSPYANFYNNSWPYLVGWFINYIPYCLMSRNLYLHHYLSALNFGILLLSQYLNYRVAKNKIIGGIITATIFVSAIYCFYEFIPITYGLPWTLDQCNSHKWFPNWDIDCMTYTG
The following text describes a protein:
Function:
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Sequence:
MKFFVSTGEASGDLHLSYLVKSVKARYKDVDFVGVAGEKSQKEGVEILQDINELAIMGFTEVLKKYKFLKQKAYEYLQYIKDNQIKNVILVDYGGFNVKFLELLKNEIKDIKIFYYIPPKVWIWGEKRVEKLRFADYIMVIFPWEVDFYKKHNINAIYFGNPFTDFYKKVERTGNKILLLPGSRRQEIKAMLPVFEEIINNLKDDKFILKLNSNQDLKYTENFKKYNNIEIIIDKKLKDIVSDCKLSVATSGTITLELALLGLPSIVVYKTTFINYLIGKYILKIGYISLPNLVLNDEIFPELIQKDCEAKNIEKHMKKVLENLPEIEEKIENMRKKVEGKAVVESYADFLVKEGK
The following text describes a protein:
Function:
Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3). Involved in regulation of flowering time. Required for the expression of the MADS box genes and flowering repressors FLC, AGL27/FLM and AGL31/MAF2. Required for histone H3 trimethylation on 'Lys-4' H3K4me3 at the FLC and AGL27/FLM loci. Involved in the control of seed dormancy and germination.
Subcellular Localization:
Nucleus.
Sequence:
MASVYIPVQNSEEEVRVVLDQLPRDASDILDILKAEQAPLDLWLIIAREYFKQGKIEQFRQILEEGSSSDIDEYYADVKYERIAILNALGAYYSYLGKTETKNREKEEQFISATRYYNKASRIDMHEPSTWVGKGQLLLAKGEIDNALQAFKIVLDTAPDNVPALLGQASVEFNRGRFSESLQLYKRALQVFPGCPAAVRLGIGLCRYKLGQLDKARQAFDRVLQLDPDNVEALVALGIMDLQANDSIGMRKGMDRMQQAFEIYPYCASALNYLANHFFFTGQHFLVEQLTETALAVTTHGPTKSHSFYNLARSYHSKGDFEKAGMYYMAAIKETNNNPHEFVFPYFGLGQVQLKLGELKGSVFNFEKVLEVYPDNCETLKALGHLYTQLGQNEKALEYMRKATKLDPRDAQAFVGLGELLISSDTGAALDAFKMARTLMKKGGQEVPIEVLNDIGALHFEREEFESALENFKEALGDGIWISFLDEKENLEQTGVSVLGYKDTGIFHRLIESGHSVDVPWNKVTTLFNLARLLEQIHKTEAATFMYRLILFKYPGYIDAYLRLAASAKAQNNLPLAIELVNEALKVDDKNPNALSLLGELELKNDDWVKAKETFRAANDATDGKDSYAILSLGNWNYFAAMRNEKRNPKLEATHLEKAKELYTKVLTQHNSNMYAANGSGIVLAEKGQFDIAKDVFTQVQEAASGSVFLQMPDVWVNLAHVYFAQGNFALTVKMYQNCLRKFFYNTDSQILLYLARTHYEAEQWQECKKTLLRAIHLTPSNYTFRFDLGAVMQKSSSSTLQKKKRTADEVRSTVAEAENAVRVFTQLSAASDLHVHGFDSKKIQTHVQYCSHLLEAAKVHREAAEQEELQNRQRLEVARQAALAEEARRKAEEQRKYQLEKRKQEEELRRLKQEEEKFQRIKEQWKSSTPGSNKRKDRVEDDDGESKPSERRRKKGGKRRKKDKSSRARHYEDDEEEAATMDDHNEVEDEDANTNYNREDEMTTQEAEEPVDDDAHDLLAAAGLEDPDVDDDEVPTSGVRRRRALSSSDEEGELMEESHPNSSPQKEKEESNGEAGDPNMEEEEEEEEAN
The following text describes a protein:
Function:
Antibacterial activity against M.luteus and E.coli bacteria. Antifungal activity against N.crassa and F.oxysporum. Presents chitin-binding activity.
Subcellular Localization:
Cytoplasmic granule. Note=Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Sequence:
MRLVVCLVFLASFALVCQGQVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYSG
The following text describes a protein:
Function:
Probable methyltransferase.
Sequence:
MELFNKAKLIEESDKGRYVEATDILKPGDSLFSENSFASIPLENFLYKKDYCFNCCKYQISTEQQTSEQPKSTPGFPFQCKYGCNMWFCSNECADGMVHQLECSFISKFVELSLKHDCDASISLLALRVVMKNKVASEVFEQTVGKLTNQKSIFIQNNKSFLDKYSKLFDQVYLIVKSENSELSSIFNKEEYLEVVCSIFVNSFAGLSNNFNRTPISNGYFYKAALLNHSCEPNTFFSIQNSTLEMRVVKDINKGEQIFDSYVDLLLPTIERQKILLKSKNFVCDCSRCTDITENSRFVSSIHCIFCKDETNYISPKVKYDDKTKILKQVWSCSKLTCQFNKKNNNKNNQEFLNILSDVAKFYDFINNDLLFKEEKKEEGEEQIQPMVEPILNRLVEYETNILSKLHENHHCWLLYHLRLSKLFERFSAVFNSFDYLSQSIQHYKEIARIVECVIKSPSSEIIDSYYHLARVNEKYLLSLINQRNNHIKQLEKQKQRDTTIDIDSLNKDIKNLLKFINTTYKKAYEMALICYGNFKPKTLLLNALVEKSNFSSSN
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MSKQTPIISMLTKYLGVRRNKMWLRYKEDMSPRTIPKPNLPPGCNSKLSGNYYYTRDARREMAPPVVLAENTSARLTPGVSDSSSLESTQTNLPTPGFSTKWTLSTDQPYLRK
The following text describes a protein:
Function:
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSVFMSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMLSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCRLAACLRNPAFFRR
The following text describes a protein:
Function:
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Subcellular Localization:
Cytoplasm.
Sequence:
MSQNILRHELIGLNLEVVKSTDSGLISTKGRVINETRNTLVLEKENGKEITLVKEISTFRIQFESENVVKIDIDGRLLVGRPEDRLKRKIKQLYSY
The following text describes a protein:
Function:
Transcription factor that governs genes involved in reductive and siderophore-mediated iron acquisition, and carbon metabolism. Suppresses the expression of sreA and induces hapX to stimulate expression of genes involved in both reductive iron assimilation and siderophore-mediated iron uptake which is essential for the maximal virulence. Also regulates genes involved in gluconeogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MGCRKSSCPRHHTPKAGTFPPRWFPSAEEPGKKGGQPARPTVVISAGTSEHETITIARRRRTPQLKARHLLSAPANASDLSSSKLIFDVCRSPSDLLLRVPTTNSEHQQAELCATALRPTRSKRLMTENGTAQTGTVPVEQPRNGTMENAKLNMAEGDSSRMESGSKNTASPPVKADNNAAGTHSSPKKRRKVNHACVYCRRSHMTCDSERPCTRCIKRNIGHLCHDEPREPSKRARSEHEHSTAEEDGHSNNEFSNAQSMPRNVDVQDAAGQQILPDGTVALPPSSVSAVQHNTIPSSSAQNSLGHNSQQLLGYNEWLGGQSQFQDMHTFHPSYMFNAPEVTNEYNLLGDFLSSSLLDDGGMFSNDNLQGIYSDPTLINSMANLDNTALLQQAQPSQPTQSQPHQNDSVQGPSSTVVNDKARETYYMTAADPSGSDPPEERMNKLLKAKYDAGLLKPFNYVKGYARLNQYMEKNMKQSSRQKILRQLDKFRPKFRERMQSLTDIELILVEMWFERSLMEYDRVFASMAIPACCWRRTGEIFRGNKEMAELIGVPIESLRDGKLAIHEIIVEDQLVSYWEKFGAIAFDNTQKAMLTSCTLKNPNSSNPGNGIPCCFSFTIRRDNHNM
The following text describes a protein:
Function:
Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells.
Subcellular Localization:
Secreted.
Sequence:
MRHLGAFLFLLGVLGALAEICEIPEVDSHLVEKLGQHLLPWMDRLSPEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLGSAFSEDDSDCHGKPSMGQLALYLLALRANCEFVGGHKGDRLVSQLKRFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHKKRVHGSVVDKLLYAVEPLHQGHHSVDTAAMAGLAFTCLKRSNFNPRRRQRITMAIKTVREKILKAQTPKGHFGNVYSTPLALQLLMTSSMPGAELGTACLKASVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEVISVTLQVLSLLLPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPDTPLLQGIADYRPKDGETIELRLVSW
The following text describes a protein:
Function:
Upon coexpression in E.coli stimulates the diadenylate cyclase activity of CdaA about 20-fold. In B.subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MDKFLNNRWAVKIIALLFALLLYVAVNSNQAPTPKKPGESFFPTSTTDEATLTDIPVKAYYDDENYVVTGVPQTVNVTIKGSTSAVKKARQTKNFEIYADMEHLKTGTHKVELKAKNVSDGLTISINPSVTTVTIQERTTKSFPVEVEYYNKSKMKKGYSPEQPIVSPKNVQITGSKNVIDNISLVKASVNLENADETIEKEAKVTVYDKDGNALPVDVEPSVIKITVPVTSPSKKVPFKIERTGSLPDGVSIANIESSPSEVTVYGSQDVLDSLEFIDGVSLDLSKINKDSDIEADIPLPDGVKKISPSKVTLHIEVDSEADQKFENVPIKTVGLSSSQNIEFLDPESQAIDVTAKGSPTNINKLKKSDIELYVNVSDLEDGEHSVKLEVNGPQNVTWSLGRKNAKIKLTSKKSNTSTNDNSSNTSGNQDTDKQTNDQKNNQQEDTKNTDKNNNDQNQDGNKDQNQDQDEDESTANSQSSSE
The following text describes a protein:
Function:
Does not exhibit any ribonuclease activity.
Subcellular Localization:
Secreted.
Sequence:
MKPLVIKFAWPLPLLLLLLLPPKLQGNYWDFGEYELNPEVRDFIREYESTGPTKPPTVKRIIEMITIGDQPFNDYDYCNTELRTKQIHYKGRCYPEHYIAGVPYGELVKACDGEEVQCKNGVKSCRRSMNLIEGVRCVLETGQQMTNCTYKTILMIGYPVVSCQWDEETKIFIPDHIYNMSLPK
The following text describes a protein:
Function:
Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.
Sequence:
MNGKMDRRKKRTSSEQYQMYIDMMESDPIFATGRVPRDYDLNYLTKKWKELSDRLNKCSSGPTLTPEEWRKRLNDWKNTTRCKYRRSLLSTEKDISMTSVETRALDLFGKVPTTGGETMLNLKSEKDEHDDEMEELGQRTSVAFQKELQAAVEEAINDEVDEEEMVEEHVDHEDMMEENLAETGITASTTAVNTGGGTYRTIVVDNTSFEHVEEDPQTVQPHAVEYVTSRRPAAPVINPGTASSGNKLINGELPVKRMRTQPREQIIYEVKNAPRCISNMQAVPPLHSTKLEREPSSLTSALSSSDAQQIAHQLKRLADIKFETLQFEIARFKFNNPGFQYDPPSL
The following text describes a protein:
Function:
Required for branched-chain fatty acid synthesis (such as (omega-1)-methyl-fatty acids). Catalyzes the reduction of the 3-keto-fatty acyl-CoA intermediate that is formed in each cycle of fatty acid elongation. Very long-chain fatty acids (VLCFAs) serve as precursors for ceramide and sphingolipids. Involved in hormone production as it metabolizes 4-androstendione (androst-4-ene-3,17-dione) into testosterone and estrone into estradiol (17beta-estradiol) in vitro, but the physiological steroid substrate is unknown.
Sequence:
MACQCFLVGAGYVALAAVAYRLLTIFSNILGPYVLLSPIDLKKRAGASWAVVTGATDGIGKAYAFELARRGFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTNAAPSAYKDLLATLNQVEIGVLINNVGMSYEYPDVLHKVDGGIERLANITTINTLPPTLLSAGILPQMVARKAGVIVNVGSSAGANQMALWAVYSATKKYVSWLTAILRKEYEHQGITVQTIAPMMVATKMSKVKRTSFFTPDGAVFAKSALNTVGNTSDTTGYITHQLQLELMDLIPTFIRDKILTNMSVGTRAAALRKKEREAKSQ
The following text describes a protein:
Function:
Non-essential cell division protein.
Miscellaneous:
MISCELLANEOUS: Overexpression induces cell filamentation.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein. Note=Localizes at the septal ring. Recruitment to the septal ring requires FtsZ.
Domain:
The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.
Sequence:
MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDIELDDTDDRRPTRAQKERNEEPEIEEEIDESEDETVDEERVERRPRKRKKAASKPASRQYMMMGVGILVLLLLIIGIGSALKAPSTTSSDQTASGEKSIDLAGNATDQANGVQPAPGTTSAENTQQDVSLPPISSTPTQGQTPVATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPATVAPVRNGNASRDTAKTQTAERPSTTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASPAQTTATPAAGAKTAGNVGSLKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVSGVYASKEEAKKAVSTLPADVQAKNPWAKPLRQVQADLK
The following text describes a protein:
Function:
Essential for pronephric tubule development, acting upstream of pax8 and lhx1/lim1 and downstream of retinoic acid signaling to induce pronephric mesoderm to form pronephric tubule-specific cells.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MFSLQHVLLILISLGQVYSQQVHHNAGRKFPQWLTGLIAMTVFLFLVLVVYVAKMFWDKRSQESINMKDIEEVVANGTSECCEARKENQYISCNMKDLRSSEHIHAYENPIEVNDNVRSTAM
The following text describes a protein:
Function:
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MSDDEGGSLMFRAFSVPDTGEEYDLDIPPTSGNEYLRRVQQEAYNCPDVVVANLDTSKFTSRQTVRFNDSSECAPPPDGFAPTLEWQKEQVANFSATRQLLARHKALMKKSKAKCPVRLPRADDKERWRSVCYGSAPPAIAPLLSIVSAIPQHTVDNLINYNTQWIQEKGFCIEMGVWLYALLACLEKPLHPEACSNIRALARACASARRSLTSKSDDRLLPLNLIICLTARYFGQQDLADP
The following text describes a protein:
Function:
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, NBN, FOXO1, UBP43, YTHDF2, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-dependent manner, thereby regulating cell migration. Following phosphorylation in response to DNA damage, mediates 'Lys-63'-linked ubiquitination of NBN, promoting ATM recruitment to DNA damage sites and DNA repair via homologous recombination.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDPPSNKGRLPLTNVSNNVNQRQCKSNVPPPHHDPLSEEQLKYAPHGSEEAFFMYRKNQRKATYGEEDLFSLLSDEVLLHILKWLPKKTLLSCGQVNRRFNRVSKDETLWYRLDLSNRTLQFDGLVEVLSRGVIVLRLAQTSIVNPTPDSNYLEFPACIKVQYLDLSMCTVSLAVLGALLANCRALVKLSLENVPLDGRICAEIAENRKLEALNLTMCSGIDATGMRLMAKALTRLHSLNVSWTSLSAEAVQELVRNLTPQIVHLNLSGCRSTLTDEKVAVLIKRCTKLVALDLSDCTPLTEVVIKTLCKARKIEYLSLSRCYNIPVTAYLNLTELKTLRFLDLFGLVSDQAIATLKNSLVDIGINKYYHSSVARPTVGTKRTSIWGLRTRD