lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling.
Subcellular Localization:
Secreted.
Domain:
The conserved ExDxxE motif might be important for catalytic activity.
Sequence:
MIAKSFIASFLFLCFAFSGVKADGCSEENGYYYCNQASEVEFTNVGYSSTYNEITNMDTSSCSCSSTPKSYGGNLAPFDEEFSFHFRGPIELKRFAVYYPDTSNALSSLRKRSNNQHMKRHPHHKRDDVIDSTLTVYETVMYTTAVYGDSATTPAASEAQASSDILSSLASLSSASTDNLAASVTPTTVAASVASSVDTDSASATISSVVDSATSSVSTVIPSSIISAAPPDSASESTPASTSYASSTTSATSTSTTSGSSGSSDWGRSSFYEADSGTSDNIVFLNNMGGSAGSGVWSSCFGNSLSFAASNGVDGASSSQVLENILVASDKEFSIWTATECNNDCGYYLPGIPAYHGFSGAKLVLMEFIMPHDSSSSYNQDMPAIWSLNAQIPRTLQYGNADCSCWTTGCGEFDIFEVLSTGNEKMIPTLHGSQGSSNGNGGGAGSSDYFARPTSSSMIGAVIYDTSSSGIYIIDVTDQNVSFDSTYSASDVDAWLQSGATIVQLSS
The following text describes a protein:
Function:
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
Sequence:
MFNYRREVLLDLWRKMPEAAACETVAPPEAVKGEEKRQQSVVKTQLDWLSEELKLSSSIIQSDYKVYAAFVHRRWVFMQLRRLAESALGNVGKRSKPAAPAGCQLGECAAAGEFDLPEEVLFWAKALLKEKRQGDALLAMDERNFHAWEFRRWVMYQLGQMEDLFVQSSIQFGPAVVGIKEREFASYMNGSAKSDRPRDLFFTPTEVKELNFTSAAVRRNFSNYSAWHQRGFIMQGALRRLQQRQWREEEADNNLRDGMLSQAWGQLEEDLTLLTTAIYCDPLDQSAWYYAKFLIHASKQLTALPFASTAVPIDITAKLDEVCLDLVGEERRLGEDMETYWPYLHLATSLLTSIKKSNDGNSSDVISDRQSALKLAREVWAALQPQGRHVNGDDDCIKCLQELCAHLTTADPLRAGMYKYFLSEVTTA
The following text describes a protein:
Function:
CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein.
Sequence:
MVVENTKRLQVLTKQRVISSVVLLALAGAGAYGFLYAGAKEKSHSEVSSQSRRNAQNFTPTPSEWATLTIEPVKAKTFRAEYVTEGKVAVDEDRSTPVFSPYAGRVTKLLAKPGEMLKQGQPLFTIEAADTVQAQNDFIAAMTSQNKAKSAIDLADIQFKRAKDLYEGHAIPLKDYQQAEATQVQAQNDMRSSATALEAARNKLRILGFTDETIKAFQDKGVIDREITIYSPISGTVVQRKIGPGQYVNSGASDPVFVIGDLSTVWLTAFVRESDAAAVCIGQDITVNVIALPGRPLTAKINYVAAAIDPSTRRLLVRATIDNKDGALKPEMFANVTIYSAGDRAAPAVPKQALIYEADKVRIWVAREDKSVELRQIKIGLINGNLVEVTSNLQPGEQIVTKGSLFIDRAASGS
The following text describes a protein:
Function:
Metalloprotease. Acts in the basement membrane to control directional migration of distal tip cells (DTCs) along the body wall basement membranes, a key step that promotes gonad morphogenesis. Regulates DTC migration probably by recruiting fibulin fbl-1, type IV collagen let-2 and nidogen nid-1 to the gonad basement membrane thereby promoting the remodeling of the basement membrane. During larval development and probably upstream of basement membrane proteins fbl-1, let-2 and nid-1, regulates pharynx length, probably by regulating pharyngeal cell length. Does not recruit fbl-1 to the pharynx basement membrane.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Secreted as a zymogen. The zymogen localizes to the basement membrane of gonads, intestine and hypodermis. The mature and active form displays a similar localization but only during the L3 larval stage.
Domain:
The propeptide is required for localization to the gonad basement membrane; The disintegrin domain is required for distal tip cell migration and partially for mig-17 localization to the gonad. Required for the control of pharynx length; The PLAC domain is required for distal tip cell migration but not for gonadal localization.
Sequence:
MHTFCILIPTFLVLVWTTESARREKQQSNDISFVKRKVQDGLKFSRVIKYTNETIQGMKTNFNSNKTQELSLDVLVVADFLSYQAFLEMSNGDSHRAIHNLKEYLHALFEQTKIIYDGISFGNETLHMVFAGTWIATQERDCPLWISWAEEEEERVLNEEIRRLEEKERDLNSTFVDDTFFMNSTDSDNSSTDALISSDMPKKLRKFVDITLEEMQENNSTEMTLKIDSKKAIDKFTIWLKEQTGLPRHEHAVLITKFDLISINGNSATQGMAYVGNICENGDSSSVVEDIGAGLTSLIMAHEIGHSLGALHDGAYETAECDSNDNYLMAVAVSGSADRQSFLNSRRMSNCSINSIIENLKEPTANCVKKWKTKKGKDVSQKDFIKKPGELVKITRQCQVAFGPTFIPCLHIGYFHEQSICERIWCSDGESDECQTLNYFPAFDGTECGYNMWCLEGSCVQNTKKWMDCKDINSKTCSKYSTSKLKHYCKSKDFREICCRTCAKKGKIY
The following text describes a protein:
Function:
Involved in DNA repair and RecF pathway recombination.
Sequence:
MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSNLKGALQPFTPLLLRYSGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLNCIQALAGTTGSPEPALRRFELALLGHLGYGVNFTHCAGSGERVDDTMTYRYREEKGFFASVVIDNNTFTGRHLKALEAREFPDVDTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTKKD
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Subcellular Localization:
Mitochondrion.
Sequence:
MFKLAFRSIRAPVARASFVKPIRFYVAPPISKDEVTSRAIQALKTVAPLQESNITLESSFQKDLGLDSLDTVEALVALEEEFDLEIPDKISDEIKTVGEAVDYIYKEESK
The following text describes a protein:
Function:
Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA.
Subcellular Localization:
Mitochondrion.
Sequence:
MFASKLLRVPYRKSIRKVVTSAEKLSLTSAAVDTFYQNEKKKSIKTDIVPHKTFINRNPRNLERLALAHKDQGWGKGIPDRPATNWPTGSYHHRILFEVTGKHTYASLLHYHGNQVVAVSTREWSIQKMLYKGNDVSACYNIGTIFAERCIRAGISCAAWTIPQNMVDNSDRIKSFCTAVVETGFVLEEPDQISFKSFQPPHVEKKGPRPPRRV
The following text describes a protein:
Function:
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. Acts as a regulator of mitosis/meiosis required for progression through meiotic prophase during oogenesis and spermatogenesis and for promotion of the entry into meiosis from the mitotic cell cycle. May act by regulating and activating gld-1 mRNA activity in germline. Required for polyadenylation of neg-1 mRNA during embryogenesis.
Subcellular Localization:
Cytoplasm.
Domain:
In contrast to other poly(A) RNA polymerases, lacks any RNA-binding domain. RNA-binding is mediated through its interaction with gld-3.
Sequence:
MVMAQQQKNAERNDEHTRRNRSPSVDSVSRVQQQSGGFAFYNQQSNHQYQQSHPRRTSFSRDGNTGYYNNHSGNKRQTYNNQRGGRSYNHRGNSNYQQNGEYSGNQGCVPKYHQRNQNYPQLQPKYSYFQPHQRPIFNSTQGYGTYSVRRSSPPSPSALSSSTANSTSNRAPTQPPILLRHAEPASDKNHQGSDHEQNHDPKIHLYRSAGTAPGGYTQCPSPYKQPPPQPPSTPSSSDKRIEQQQAEDWPTRFQHPPPQFRRGQDPMPASIELQHKTANQTMPVDIVQTNQQKTVSSYERAAQFRASASELPTDSVDAKHPCFANERMQSALIGISPQLKTQQQSPGIPIQNEAEASAVMKAMRSFQFHNWPQMSHGSYYPMPYHLENQMRPMKSGDQLPLNQQNHNLSGFPAFVGKSSLVGSSLNTRNSSEADPEEMPRIMEKLDDEVTGADHDKTIDENRRRIHKSQEPRIGTEEKALNELPRKANRRNSSCSSISSVSESSSPSALDESTLTKILPTDNFRGGRGFASPSPPTSLLSEPLSRMDVLSEKIWDYHNKVSQTDEMLQRKLHLRDMLYTAISPVFPLSGLYVVGSSLNGFGNNSSDMDLCLMITNKDLDQKNDAVVVLNLILSTLQYEKFVESQKLILAKVPILRINFAAPFDDITVDLNANNSVAIRNTHLLCYYSSYDWRVRPLVSVVKEWAKRKGINDANKSSFTSYSLVLMVIHFLQCGPTKVLPNLQQSYPNRFSNKVDVRTLNVTMALEEVADDIDQSLSEKTTLGELLIGFLDYYANEFNYDRDAISIRQGRRVERAALAVRPKIHSNSEGDKETPPPSSSASTSSIHNGGTPGIPMHHSISNPHFWRSQWRCVCIEEPFTNSNTAHSIYDEMVFEAIKKAFREAHGELQHNHDLDKLMECEPIKASTTNTGAAVFAATYEGERPLAQQPNTIACASLRVLNSIPVSSGPGHYHYQQQSNQNLSRPQRPGSNQGYQMNNNRGFNGNNQQQHQNRRSFNNQSSSNPGNGSTGPRSSRSNENVRDSSRQQNSQKGSSGVSVSKENVASTTGVPVDKKQQNSNRKDDGNRTKRSPMVQSPEPAKTKSEKTPMASSNVSQ
The following text describes a protein:
Function:
Has an integral role during the infection of macrophages in the mammalian host.
Subcellular Localization:
Membrane.
Sequence:
MSHVPAVLWRMELWLCALFIYAAFTTAAAPSSCGHSQIVHKQGHLPLTYAALRNNGNGLRYQVEMDLERWNGSATDEQRAVEPQATVTISSDREDSEWAPIRIAVFMPDLEDESKYCTAIGQMRPDSSGSLVPCTSNADLLTDAKKTVLINSILPQAVNMHAQRLKVRRPAASTSIVVNSMPGSYCGSFTVPTAHRTTGVPDADFVVYVAAGPTSTPKSFIAWAVTCQYYPNTATVTSRPAVGVMYFNPRYLPTSEGETQEHVDRYGGNPSGSTNRLRRVASHELLHALGFTSSVFKARGMFATVPSLRGKRNVPVLNSSAVRAAAKAKYGISDTEVFYGVELEDQGAPGTSLSHWKRRAAKDELMAPVFGLARYSSLSLAALEDMGFYKVDFSKAEPVALGATAGGKLFTEPCLTEGTSNTPTVFCDSLSASVRSCTADRLSIGRCALTTYSSALPSYAQYFPNQPTLGGSLSHSDYCPVIQPLSNTGCSGGSLGAMPGSITGDNARCFDADNLLVKFTFTQPGAICAKVHCKNASRTYEVLVIGANSWLSCGAGGTGVTVQPAVSSPNVFLKGGRIACPPYDDVCYANPVAFAEVEAPPTTSTTASPSAATAATHGMVVSGLVAVAVLLGVCIC
The following text describes a protein:
Function:
Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
Subcellular Localization:
Mitochondrion.
Sequence:
MFRLARTANLTWRVSAPRMSRAMSDEGAIRQEGGKLAKKAAADENQYVRQLEAEQLKALRKHHLEEIEEHKQVIERLQSRIKQHEEKLQQIKPPVTK
The following text describes a protein:
Function:
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Subcellular Localization:
Nucleus.
Sequence:
MSELKDCPLQFHDFKAVDHLKVHPHYKAVLAHSEDDGISIEELDTLQLELETLLSSASQRLQQDKKGDRRFLKLGGDHELGAPPKYEKLKKQKLEGKVGHGPGPGPRGRGFLLDFLGPTTCHGPPRMIRFWASVEPYCADITSEKVCTLEKLLKPPEDEAEHYKLPPLRKHYSQRWAQQDLLEEQKDGAWAAAVTDKKKGLMGPLSQLHTKDLDALLKKSEAQHEQPEDGCPFGALMQRLLQALVKENITSPMEDSPIPDMSGKESGADGASTSPHNQNKPFSVPHTKSLESRIKEELIAQGLLESEDRPAEDSEDDILALSAHNRVEKHDMLRLGKGR
The following text describes a protein:
Function:
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
Sequence:
MAEKDIDKLLSLTDSKYRLSVVTAKRALQLRSGAPSVLPVEQRVRTHNLVTQAMRELATGQLTVGTNLIDEQRFHQDYVRQRQAQLQAQLNAERERERD
The following text describes a protein:
Function:
Plays a systemic role in water and solute homeostasis.
Subcellular Localization:
Secreted.
Sequence:
MIKMAVKFVVVMIVFAQILAPIAEAAQGKAVYYDPPYTRSACYGTQRETLVVGVKNNLWQNGRACGRRYRVRCIGATYNFDRACTGRTVDVKVVDFCREPCNGDLNLSRDAFRVIANTDAGNIRVVYTPI
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
Sequence:
MQSATMRTSAFRPAAVSRRSAVTVRAVQEVKGVVVSTKMNKTVVVEAERLATDVTYQKRKKVTKRYMAHDESGALRVGDFVRLDGTRPLSKTKRFSVTEVLRKAD
The following text describes a protein:
Function:
Calcium-dependent mitochondrial carrier protein that catalyzes the import of ATP co-transported with metal divalent cations across the mitochondrial inner membrane in exchange for phosphate (Pi). Can transport phosphate, AMP, ADP, ATP, adenosine 5'-phosphosulfate, sulfate and thiosulfate, and, to a lesser extent, other nucleotides. Binds calcium ions Ca(2+). Also mediates calcium uptake (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Domain:
The N-terminal domain can bind calcium.
Sequence:
MESSKPKNRNPMKKPVSITMEHVLLALRETMDEREIRIRSLFDFFDNSNLGFLDYAQIEKGLASLQIPPEYKYARDLFRVCDANRDGRVDYQEFRRYIDAKELELYRIFQAIDVEHNGCILPEELWEALVKAGIEIDDEELARFVEHVDKDNNGTITFEEWRDFLLLYPHEATLENIYHHWERVCLIDIGEQAVIPDGISKHVKRSRLLLAGGLAGAVSRTATAPLDRLKVVLQVQRAHAGVLPTIKKIWREDKLMGFFRGNGLNVMKVAPESAIKFCAYEMLKPMIGGEDGDIGTSGRLMAGGMAGALAQTAIYPMDLVKTRLQTCVSEGGKAPKLWKLTKDIWVREGPRAFYKGLFPSLLGIVPYAGIDLAAYETLKDLSRTYILQDTEPGPLIQLSCGMTSGALGASCVYPLQVVRTRMQADSSKTTMKQEFMNTMKGEGLRGFYRGLLPNLLKVVPAASITYIVYEAMKKNMALD
The following text describes a protein:
Function:
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
Subcellular Localization:
Nucleus.
Sequence:
MDPEQEISNETLETILVSSTKGSNNNNKKMEEEMKKKVSRGELGGEAQNCPRCESPNTKFCYYNNYSLSQPRYFCKSCRRYWTKGGTLRNVPVGGGCRRNKRSSSSAFSKNNNNKSINFHTDPLQNPLITGMPPSSFGYDHSIDLNLAFATLQKHHLSSQATTPSFGFGGDLSIYGNSTNDVGIFGGQNGTYNNSLCYGFMSGNGNNNQNEIKMASTLGMSLEGNERKQENVNNNNNNSENPSKVFWGFPWQMTGDSAGVVPEIDPGRESWNGMVSSWNNGLLNTPLV
The following text describes a protein:
Function:
Probable transcription factor. Together with STOP1, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation.
Subcellular Localization:
Nucleus.
Sequence:
MHIHMMNRDEHIAKKVEGSISSFSGETSTSSKQIYVNPVTTTGTKSMEDDDVSLSLLYNLSTLHEKVHQIQSLVSFYMVSTNNINQSSGSTSLAVANIGSLVQEIITAASSMLYTCQQLQIGSNNNNNDIDNDQTVDAMVLEFSRQETDPGHDFVQESTNLFGVQERGQISFPDQNLDWYNTETINPKKDKHRSKPSSGSYDILELDVADLLAKYTHYCQICGKGFKRDANLRMHMRAHGDEYKTREALISPTSQDKKGGYSLKKHYYSCPQHGCRWNQRHEKFQPLKSVICAKNHYKRSHCPKMYMCRRCSVKHFSVLSDLRTHEKHCGDIKWVCSCGTKFSRKDKLMSHVSLFLGHVPAHGSSKPPTITLK
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MVPGSEGPARAGSVVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTENLVQQIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPTDVSQDPRHMVLVRGLVLPVGGGSAPGPLQSKQPVPLPPATPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAPQLPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQQRGMGGQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGTVGASGATGQPQPQGTAQPPPGAPQGPPGAASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI
The following text describes a protein:
Function:
Forms chloride channels.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane.
Sequence:
MSSNISMQYSTRNERVNAITEIPLNNLNASQQQTSTTAVPIWHNNTTKHPAISSILDTPAQQSRSSVFGESFLTLFQWKGSIYKALWKHFVIYCALYYLLTVVHKVALNGEQKKAFEALAKYCMTNPPSPTNLIIMLSFFTTTAMQRRFSVQINMAGTSRLISVFVMGLKPNLREGPVIVEHYARWVVLSWVLTYRIVCKPLRDLFPRYSRRLNVLMLIRKCNEFYFFKDMTSLQRAGIIQNSAERMILEKMETEGDPTPRPLVVIDWMTLLIKKTHKKGRFAEYKYYLQSVENVLAYKKNCGNTIKFATKNIPYALIQVAVIVVYLYGVFTLMARNFDGVEKSVLLGGIVNYFPGFSSIQFFIFLVWLNFGRTAVNPFGSDDDDIDVKQLLATHIQDSLRLAKLYHQDLSDFLGEIVLPNQNAAASAAK
The following text describes a protein:
Function:
Acts as a RAC1 guanine nucleotide exchange factor (GEF).
Subcellular Localization:
Cell projection, lamellipodium.
Sequence:
MNPEERVVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLISRLLPGSVEKYCQEPQTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNTLLAVNKATEDQLSERPCGRSSSLSATTSSQTNPQAAVPSTTPEQQSEEKAAEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAVKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKSPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKSLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKVPIAGMVVTRLDEIEGNDCTFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPASCSSLSKTSSSSCSTHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKTSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDESIRAESSSKTSILQ
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MLRHRFPPLGGGTARPTDLIRRKSTGLPFPGQQSPSPDDRMLSRLSKFGLSLPRLGSVPPARFVSQSKQNSSAGSSAVTELHNREEKSEHGEVSQYVKNPDYHGFSSDPVADEWNMKVGFFMGISVALVIGGTFIHYLPDHGMRQWARREAERIICQREQQGLPLIEENYYDPSKIILPSSREE
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Sequence:
MSQRSLFSYFTAKNPTTPASSPVMKKQTAIRSLKKISSKAKDSSSDFELENTESESEDEKEFNKVASEEKIMKLNKPSSSEYESESEQNFIDDDSDEEQKTPSKSRTRAKPAKSTKSRSIKTTKAAVPFDAPPEVNHAQIAREASASVSEEDLPDWLTTKLRDKNKKRPDKEGYDPSTVYIPETVKETFTPFQKQFWDIKENNFDAIVMIRKGKFYEMFSVDAIFARDVLKLHLTYRGKEPMCGVPEKAFSEWAIKIINAGKRVCKVEQMETAIDQANRKGKGAEKAIQRKLVQVYSLGTIDDFEMLESSQPSYLLSIRSSSRQTAGVCLVDCSTGTFHLGAVNEDDLADTLIRFEPVEVIYSANNISPEHLAIIKHYCGNVATRAKTGSETWDSTLAMNTILKIAKWDNVPDSLENVHQDAIAALGGCVAYLNEHKIAESLLSLKRFKTLDEAGSSSFLSLDSSALTNLQIIGKDPHCLINILDHCTTPFGRRRLRFWIMHPLRSINQIEERQKAVEELMKPDFNTLSKELKTIPDLERMLSRVYSNKCSVKVFIDCLGALKKCCQFFTKIEGTVKSPLLANVVPPGKGKSLAKQIDDILAELEVEKSIQSNEFIVKKGVFKDIDDIDEEVSSIEDDLNDILRDIKREVGCKDLSYVNMQSEKFQVQIPVKYCSDLPDKYILMSQTKSVRRYHTPEIKEKLKQLDIVENERQKLRSGSQKRFIDEFAKNSPIWDSIVDAIADIDCLISLAMTSIRWRASGVLCKPIFVQKDSPEAHGQAILQVEKMNHPCIIGTPIPNDIDIHDRFVLLITGPNASGKSTYARMCCVSIILAQIGCMLPAVSAKMTCYDQIFTRIGASDRIFNGQSTFAVESSETARLMKHATSDSFVVLDELGRGTSTLDGIAIASSVLDFFINKVKCPLVFCTHYHVLAEEFEQFPMVRNASMKYEISNGNLTLAYTLIDKMCPSSFGCRVAKICGLPADLTEEAQKVADDFEDRHAALRTSGIDVKVETIEERRDIIDLKKAIDDLTGGVVNEQNFYKFMDFLSKELPKINVE
The following text describes a protein:
Function:
An odorant receptor which affects chemotaxis to the volatile odorant diacetyl. Specifies AWA neuronal cell fate via the odr-7 pathway.
Subcellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein.
Sequence:
MQVFFKISQFFGFILTEILNILLLYLIFTKASTRFGSYKYLMISYAVYSLIYALVEILTQPIIHVHDASVFLYVDSFLKHETTISNQLAAIYCASFSLCISLLATHFAFRYFAVCSPHYLHYVDGWRLLKIYIFPIVLSTIWYLTNGFLCGPADFKTDFVKKDILEKYNEDFSKVGYIGYLYYYTDIFGNLIINWLDFLGCSINLLIMASCIGTIIICGLKTYWCMGKDRKKMSKRTKELNDQLFKTLVVQTLIPICTMFAPVGTVIVLPIFSIQIPPAIANIPSLYAGLYPGLDAAVAIFMIRDFRDAVFCWRRVLPSMMSSSRPAKHTSSHISV
The following text describes a protein:
Function:
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
Miscellaneous:
MISCELLANEOUS: Present with 2540 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSSIDNDSDVDLTEDLAVAKIVKENPVARKMVRYILSRGESQNSIITRNKLQSVIHEAAREENIAKPSFSKMFMDINAILYNVYGFELQGLPSKNNMNAGGNGSNSNTNKSMPEPLGHRAQKFILLNNVPHSKNFDDFKILQSAHTYEELIVTGEYIGDDIASGTSNTLESKLSTDRDLVYKGVLSVILCIVFFSKNNILHQELIKFLETFGIPSDGSKIAILNITIEDLIKSLEKREYIVRLEEKSDTDGEVISYRIGRRTQAELGLESLEKLVQEIMGLEKEQTKSLHDDIIKSIGDSYSI
The following text describes a protein:
Function:
Involved in the cell growth regulation.
Sequence:
MSLTITKDNIFPKGYRGRLTEGVTYDERNNTLLWVDIIQGEVHRVFLDNTNINTNTSSSSHETLKWDSSNESIGAICLTNDPNKLIICSKYGLAYGDFSSSTIEYFFKYPHTTNPDEKLRLRSNDGIIDPWGNLWIGVMNDFPIGAKEGIQPEGKLYRIGFSKESNKLTCDVMIENSLISNGLCFNNQGDEFYWTDSLTFKIWKYDYDKTTNKLTNKSVFIDLKQFYPDVEQPEPDGLVMTNNGEIYTCVFSTGTILHVDNQGKEIERIKIAAKRPTCVTIGSGIKNNEMFVTTGHLKLDDEKATIDAINLDGDLGGFLFKLKVDKDLNGQKKNIWGGKV
The following text describes a protein:
Function:
Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines. In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances. In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MKATCITILFWPLFMLLLSEERQSSKTEVKYNFTEKNYSLIPADINKNVTILDLSYNQITLNIIDTGVLQTYILLTELYLTENNVTMLYNNSFGNLSNLEILNICRNSIHIIQQGAFMGLNKLKQLHLCQNKISQLSPDIFVPLKNLILLNLQGNFISYFDVPQLFHLELIILYGNPWNCSCSLLNLQNWLNTSNVTLENENVTTCIHPGILNHYSIKTVPYNAECYSKFPPPINEDLYNHFHFISNSTFNSSLNNLKNSERKLLGKSWALLVGVVVTVLMTSLLIFVAIKCPIWYNFLLSYHHHRLEEHEAETYEDGFTGNSSSLSQVPDTNSEDTTVIFEQLHSFVVDDDGFIEDKYIDTHELHEEN
The following text describes a protein:
Function:
Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cytoplasm. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Sequence:
MDYPPGYTQSTRQRAPSTPGEEGIPPQGVDFSNMHGQIGQMMWEAGSKQIKDSFNSYGRIDLFRPYFDVEPIQVRNRLVQSFLPRKPSQISVTSDLYGPCMIVLTMVSLLLWNMKSSGYIVQNGTLMGTAFVSCFAAWIFLSGILYTVCFLLSTEVSLVHIFSLFGYSMTSHCVVLLLTSIYHPSHDHLYFFLLLGIFCLPSALRMAFYLSSKTREKTYKATLMAAVIGIHLLYITYLHFGFHVVLEEIDEILGDSPPNVAVKAAVPIAE
The following text describes a protein:
Function:
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis.
Subcellular Localization:
Nucleus. Chromosome.
Domain:
The flexible hinge domain, which separates the large intramolecular coiled coil regions, allows the heterotypic interaction with the corresponding domain of smc5, forming a V-shaped heterodimer.
Sequence:
MTTELTNVSLEEAITEKTSENRRKRDSDVLQTEEVDLSNVKRIRASRNQDNRPERQSRLQRSSSLIEQVRGNEDGENDVLNQTRETNSNFDNRVGVIECIHLVNFMCHDSLKINFGPRINFVIGHNGSGKSAILTGLTICLGAKASNTNRAPNMKSLVKQGKNYARISVTISNRGFEAYQPEIYGKSITIERTIRREGSSEYRLRSFNGTVISTKRDELDNICDHMGLQIDNPMNILTQDTARQFLGNSSPKEKYQLFMKGIQLKQLEENYSLIEQSLINTKNVLGNKKTGVSYLAKKEEEYKLLWEQSRETENLHNLLEQKKGEMVWAQVVEVEKELLLAEKEFQHAEVKLSEAKENLESIVTNQSDIDGKISSKEEVIGRAKGETDTTKSKFEDIVKTFDGYRSEMNDVDIQKRDIQNSINAAKSCLDVYREQLNTERARENNLGGSQIEKRANESNNLQREIADLSEQIVELESKRNDLHSALLEMGGNLTSLLTKKDSIANKISDQSEHLKVLEDVQRDKVSAFGKNMPQLLKLITRETRFQHPPKGPMGKYMTVKEQKWHLIIERILGNVINGFIVRSHHDQLILKELMRQSNCHATVVVGKYDPFDYSSGEPDSQYPTVLKIIKFDDDEVLHTLINHLGIEKMLLIEDRREAEAYMKRGIANVTQCYALDPRNRGYGFRIVSTQRSSGISKVTPWNRPPRIGFSSSTSIEAEKKILDDLKKQYNFASNQLNEAKIEQAKFKRDEQLLVEKIEGIKKRILLKRREVNSLESQELSVLDTEKIQTLERRISETEKELESYAGQLQDAKNEEHRIRDNQRPVIEEIRIYREKIQTETQRLSSLQTELSRLRDEKRNSEVDIERHRQTVESCTNILREKEAKKVQCAQVVADYTAKANTRCERVPVQLSPAELDNEIERLQMQIAEWRNRTGVSVEQAAEDYLNAKEKHDQAKVLVARLTQLLQALEETLRRRNEMWTKFRKLITLRTKELFELYLSQRNFTGKLVIKHQEEFLEPRVYPANRNLATAHNRHEKSKVSVQGLSGGEKSFATICMLLSIWEAMSCPLRCLDEFDVFMDAVNRLVSIKMMVDSAKDSSDKQFIFITPQDMGQIGLDKDVVVFRLSDPVVSSSALPPSTAP
The following text describes a protein:
Function:
Catalyzes a late step in pyrimidine degradation. Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta-aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide.
Subcellular Localization:
Cytoplasm.
Sequence:
MSGKDFESLEKVLEAHLPEAELKEARRLLFGKELKKLDLPRSAIDAAGQQDFDLKGYVFEASPEQLRPPRMVRVGLIQNKIVLPTDAPVLEQITALHKRVGEMVEVAAMCGVNIVCFQEAWTMPFAFCTREREPWTEFAESAEDGLTTRFCIQLAKKHNMVVVSPILERDEIHGGTLWNTAVVVSNNGNVLGKTRKNHIPRVGDFNESTYYMEGNTGHRVFQTQFGKIAVNICYGRHHPLNWLMYSVNGAEIIFNPSATVGLLSEPMWPIEARNAAIANHCFTCAINRVGTEYFKNEFTSGDGKKAHHDFGHFYGSSYMAAPDGSRTPGLSRTRDGLLVAELDLNLNRQVADKWNFKMTGRYEMYAEELKKAIQHDFKPNVMKD