lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
Sequence:
MRRFFGTDGIRGVVNEDLTPELAYKLSRAIVGYFGNVKGKKVIIGSDTRNSKDMLKSALVAGFTSGGMNVLDVGVISTPALSYLVKNQDEVLLGVMISASHNPVEYNGIKIFKNDGFKLDDDVEAEIENYLLKEDNYYRANPREIGVIYDFSHIKEKYKNYLREIINGNFEGYKVMLDCAFGSLSEIAPEVFRELGAEVVAYNTKYNGLNINENCGAVYPETSKKLFLNSGAHIGFTYDGDGDRVIAFSENGEIIDGDIMLGILAKYLKEKGLLKGDKIVGTIMTNLGLEEYLKNINVELIRTKVGDRYVLDEILKYGLNLGGETSGHIILFDYMSTGDGLLTSLFLLKILKEKGVKLSELAKDIKIFPQVHEKVSVKGLNITEDMEKRFIEITEEVINGKNIRYIVRKSGTEPVVRITLEGDVPKEYLNELVLEIKSRIIDLLSNF
The following text describes a protein:
Function:
Serine protease inhibitor with activity against plasmin (IC(50)=10.07 nM), trypsin (IC(50)=43.39 nM), chymotrypsin (IC(50)=109.25 nM) and neutrophil elastase (IC(50)=446.93 nM).
Miscellaneous:
MISCELLANEOUS: Negative results: not found in fat body, midgut and venom gland.
Subcellular Localization:
Secreted.
Sequence:
MAKLLCTLFLAGFVFLANAYSTDPPNPPDIENVFDGIPSIFNPVNWISNIASFFNPSNWVSNIPSILNPVNWVKKIIDINNPFTYIPDFLNPFHYFPKLNPIKWIPGWIPGLGKDRCLLPKVTGPCKASLTRYYYDKDTKACVEFIYGGCRGNRNNFKQKDECEKACTDH
The following text describes a protein:
Function:
Binds to the 23S rRNA.
Sequence:
MQLNDVHRGITKHRPRKRIGRGPGSGTGKTSGRGHKGHKSRSGYSRKPNFQGGAMPMFRRVPKRGFNNRWALTIFAVNVGKLNDAFNEGETVTLEALAAKNLAKGNFDELKVLGDGELTKKLTIQAHRFSKSAEEKISAAGGTAEKLAPKRTPDERVEALKSEK
The following text describes a protein:
Function:
Involved in autophagic vesicle formation.
Subcellular Localization:
Preautophagosomal structure membrane; Peripheral membrane protein.
Sequence:
MASASSALQQRVWGGRIPVVFSLDANEVTTLHAPRPFYAMVPRMSFLVSQTRDVVEYFRDAAPPMSAMQGASIWFEAKGVPLHWHLPFGLLRDLLCGPGHDGDADLPWHLTVHFLGFPSDVLLPCDNEQSVESHFMHSLKQATFLRVGSTKAVMALPEAQQTQIWTSLSQNDFESYREATRKLHLDGGVDASALRHLPLRLHLDNAPAIQMPISPLQDGREKTLLEVLNYLVPDLFPSADGADSQTHNFQLVVHGIDVPPEVSIVELYRNFSYADGFLYVVVLARSAKS
The following text describes a protein:
Function:
Prolactin acts primarily on the mammary gland by promoting lactation.
Subcellular Localization:
Secreted.
Sequence:
MNSQVSARKAGTLLLLMMSNLLFCQNVQTLPVCSGGDCQTPLPELFDRVVMLSHYIHTLYTDMFIEFDKQYVQDREFIAKAINDCPTSSLATPEDKEQAQKVPPEVLLNLILSLVHSWNDPLFQLITGLGGIHEAPDAIISRAKEIEEQNKRLLEGIEKIISQAYPEAKGNEIYLVWSQLPSLQGVDEESKDLAFYNNIRCLRRDSHKVDNYLKFLRCQIVHKNNC
The following text describes a protein:
Function:
Required for chromosome stability and methionine prototrophy. It is involved in chromosomal segregation. Binds to a highly conserved DNA sequence (5'-RTCACRTG-3'), called CDEI, found in centromeres and in several promoters. DNA-binding activity is enhanced by MET28. Required as an auxiliary factor for transcriptional activation of sulfur metabolism together with MET4 and MET28.
Miscellaneous:
MISCELLANEOUS: Present with 6890 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Mitochondrion. Chromosome, centromere.
Sequence:
MNSLANNNKLSTEDEEIHSARKRGYNEEQNYSEARKKQRDQGLLSQESNDGNIDSALLSEGATLKGTQSQYESGLTSNKDEKGSDDEDASVAEAAVAATVNYTDLIQGQEDSSDAHTSNQTNANGEHKDSLNGERAITPSNEGVKPNTSLEGMTSSPMESTQQSKNDMLIPLAEHDRGPEHQQDDEDNDDADIDLKKDISMQPGRRGRKPTTLATTDEWKKQRKDSHKEVERRRRENINTAINVLSDLLPVRESSKAAILACAAEYIQKLKETDEANIEKWTLQKLLSEQNASQLASANEKLQEELGNAYKEIEYMKRVLRKEGIEYEDMHTHKKQENERKSTRSDNPHEA
The following text describes a protein:
Function:
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MHPNISLPEPFIASMAKILPDPTQLADFIAACQRPLRKSIRVNTLKISVAEFCQRAAEKEWQLTPVPWCENGFWIDADESLVPLGNTAEHMAGLFYIQEASSMMPVSALFMGNAHYDSVLDMAAAPGSKTTQMAALMDNQGVLVANEFSASRVKVLHANIERCGIRNTALSNFDGCVFGGWLPERFDAVLIDAPCSGEGTIRKDPDAMKNWSLESIQSIANTQKALIESAFQALKVGGTLVYSTCTLSREENQQVCWHLKQTYGDAVSFESLGNLFEHASLALTEEGFLHIFPQMYDCEGFFVAKIRKLASVPTPEVNKRLGKFPFNKASHKQQAEIAQQLHKSLGIELPSDAQVWLRDNDVWLFPEALEPLLGELRFSRMGIKIAEAHKSGYRWQHQVATCLASSSASHSVELDTTQAREWFMGRDVRPEGQSGQGEVIIRYANDVIGLGKWVGNRVKNGLPRELVRDKNLF
The following text describes a protein:
Function:
Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
Subcellular Localization:
Cytoplasm.
Sequence:
MIIETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKETQEDEIILNLNDLNKSLGLNLNEIKNINPNNFGDFKYCLCAIKNTLDYLNIEPKTGFKINISSKIPISCGLGSSASITIGTIKAVSGFYNKELKDDEIAKLGYMVEKEIQGKASITDTSTITYKGILEIKNNKFRKIKGEFEEFLKNCKFLIVYAEKRKKKTAELVNEVAKIENKDEIFKEIDKVIDEALKIKNKEDFGKLMTKNHELLKKLNISTPKLDRIVDIGNRFGFGAKLTGAGGGGCVIILVNEEKEKELLKELNKEDVRIFNCRMMN
The following text describes a protein:
Function:
May be an adapter protein involved in tyrosine kinase signaling.
Sequence:
MAVPLPNDSSNAAFSWFTEYQRSCILENGVVPEWFHGIISRKAAEEMLMCKPAGYFLIRVSESRVGYTLSYRAEDRCRHFMINVLPDNQFMIVGEKTVYCSLHDLVAFHRRCPILPYNELLTVACEQGGKTNYVELLFPQKKDVSHRQVEWISSSTATNTLQSNISEENQTSQLQNNSTSHPGRLYPSLETEVSALNIQSTDQPTKPVPKPRTVFASKTPAEETPPQLPPRMRLPSRLQTSTEDRSQGLMPVIPDRQQITPNTPNEGRTQQKNQQQKPVVMSLVHIKKKLKKKRSEDHTYEEIAGGLFQKDATSALESINTNVEGLVENDYQELAEHPISDGIPKSSDRNLPVEYRHPPPFAPGY
The following text describes a protein:
Function:
Catalyzes the cyclization of both ends of lycopene to form beta-carotene, a retinal precursor. Is required for bacteriorhodopsin biogenesis, a light-driven proton pump with a covalently bound retinal cofactor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTTSYLTFLAVAVGPPLVALGVVRAARWDGDRARAAGVGILLALALSYTTPWDNYLIATGVWWYGEGTVVGRLWQMPIEEYLFVITQTLLTGLWVQALPLRPTAGFSPTRRDAVLGALAGVLVGCGGAVLLTVDATFYIGAIIAWAAPVLALQWAVGWRYLWRRRRVFAAAVLVPTLFLSAADRYAIADGIWILAGQYTTGITVLGLPIEEGAFFFVTNVFVSQGLILYAWVLARWR
The following text describes a protein:
Function:
Putative pheromone receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFSSDTFFQIFLIFQFCLGVIGNSSLLMLYVYTFFFKPHFKKLVDSVFMHLTIVNMLTIAFTLIKDIMLSFGVPNFLDDIGCKTVLFSFRVSRGLSICTTSVLSTFQVITITPSNSKWASWLKPRLSTWIFSSLLCSWLINLVIYGYMLDMVIAKTNKTHVGNGYSDGYCQNKHFGNHNSGSFFSLLLTHDLFYVAVMVWASLYMVIFLYRHYKRSQHLHSRSLSSQSSPERKATHNILSLVSCFVLIYCLNNSITLYGFYTKEKIPRLESINAILTTCYPTVCPFFLMKNNKVILQFTSSFSVLRMTCHQSSLHG
The following text describes a protein:
Function:
Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2. Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MAASLRRLSGYIGKAAIRGLVSKSQPIGFGISRNRSTQAFTQAVLNVPETKVTALENGLRVASEDSGLLTCTVGLWIDAGSRYENQMNNGTAHFLEHMAFKGTKNRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYHNTALGRTILGPTENIKSINRNDLVEYITTHYKGPRIVLAAAGGVSHDELLHLAKFHFGNLPSIYDGETLPPCSFTGSEIRVRDDKMPLAHIAVAVEAVGWSHPDTIPLMVANTLIGNWDRSFGGGVNLSSKLAQLTCHGNLCHSFQSFNTCYTDTGLWGLYMVCEPNTVEDMMHFVQREWIRLCTSVTENEVARAKNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPLPELEARIDLISAETIREVCTKYIYNKSPAVAAVGPIGQLPDYDRIRSGMYWLRD
The following text describes a protein:
Function:
Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLSQVCRSGSQSFTQRLLPWVQPTILSRSRRVQPSAIRHVRSWSNIPFITVPLSRTHGKSFAHRSELKHAKRIVVKLGSAVVTRGDECGLALGRLASIVEQVSVLQNQGREMMLVTSGAVAFGKQRLRHEILLSQSVRQALHSGQNHLKEMAIPVLEARACAAAGQSGLMALYEAMFTQYSICAAQILVTNLDFHDEQKRRNLNGTLHELLRMNIVPIVNTNDAVVPPAEPNSDLQGVNVISVKDNDSLAARLAVEMKTDLLIVLSDVEGLFDSPPGSDDAKLIDIFYPGDQQSVTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHPKVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRAEIIHHLADLLTDQRDEILLANKKDLEEAEGRLATPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRVLRRTRIAKDLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEASHSNRILHLLTQEALSIHGVKEAVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPVMGHSEGICHMYVDSEASVDKVTRLVRDSKCEYPAACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYLTFSPSEVKSLRTEYGDLELCIEVVDSVQDAIDHIHKYGSSHTDVIVTENEKTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGQDHVVSDFSEHGSLKYLHENLPIPQRNTN
The following text describes a protein:
Function:
Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity.
Sequence:
MAVPPSAPVPCSPFYLRRQEACPQCSWSMEEKAVASASCWEPPGPPRAAVPCFAIAVDQDDILPGALRLIRELRPHWKPEQVRTKRFKDGITNKLLACYVEEDMRDCVLVRVYGEWTELLVDRENEIRNFQLLRAHGCAPKLYCTFQNGLCYEYMQGVALGPEHIREPQLFRLIALEMAKIHTIHANGSLPKPTLWHKMHRYFTLVKDEISPSLSADVPKVEVLEQELAWLKEHLSQLDSPVVFCHNDLLCKNIIYDSDKGHVRFIDYEYAGYNYQAFDIGNHFNEFAGVNEVDYCRYPAREIQLQWLRYYLEAQKGTAASPREVERLYAQVNKFALASHFFWALWALIQNQYSTINFDFLRYAVIRFNQYFKVKPQVSALEMPK
The following text describes a protein:
Function:
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.
Sequence:
MLWALALLALGIGPRAYAGDHGEDTAFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYVPPVNTDDLNRIVKLARRKEGFFLTAQLKQDRKSRGTLLVLEGPGTSQRQFEIVSNGPGDTLDLNYWVEGHQHTNFLEDVGLADSQWKNVTVQVASDTYSLYVGCDLIDSVTLEEPFYEQLEADKSRMYVAKGASRESHFRGLLQNVHLVFADSVEDILSKKGCQHSQGAEVNTISEHTETLHLSPHITTDLVVQGVEKAQEVCTHSCEELSNMMNELSGLHVMVNQLSKNLERVSSDNQFLLELIGGPLKTRNMSACVQEGRIFAENETWVVDSCTTCTCKKFKTVCNQITCSPATCANPSLVEGECCPSCSHSADNDEGWSPWAEWTECSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRTCSLGKCDTRIRQNGGWSHWSPWSSCSVTCGVGNVTRIRLCNSPVPQMGGKNCKGSGRETKACQRAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKDCVGDVTEHQMCNKRSCPIDGCLSNPCFPGAKCNSFPDGSWSCGSCPVGFLGNGTHCEDLDECAVVADICFSINKASRCVNTNPGFHCLPCPPRYKGTQPFGIGLEDAKTEKQVCEPENPCKDKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNSNLVCATNATYHCVKDNCPKLPNSGQEDFDKDGIGDACDEDDDNDGVSDEKDNCPLLFNPRQLDYDKDEVGDRCDNCPYVHNQAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLMHNPDQMDQDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNSNQADHDNDGKGDACDSDDDNDGVPDDRDNCRLVFNPDQEDSDGDGRGDICKDDFDNDNVPDIDDVCPENNAITETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDKPSRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTEGQVRTLWHDPKNIGWKDYTAYRWHLIHRPKTGYMRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDA
The following text describes a protein:
Function:
Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MATQLVIYVKRVAILTLLWISCLLLLNVVDVPITGIQHFITYAPVYGVFLLGLHAALSVLLGVANFNDCSDARKELLEEIKEARADLTKRKVL
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MEENNNNDLTGKICSYLDPHMVQIILTWLKENKVGDVNDLEKNLELLNEGCDKEIALIENECTNGNRGVINNYLESVELEIDEFQEAMNEYKIDQMNRIGSNLEKKSIVGLRDWCNTYLLDKNKMYTFSDNIDDKILKLSRYYYQKKDYVKSKQYLLLYILNISEMIINISESSKMKTCYWGIISNIINSFFMNINNDDYLFSKNEDGKIIVKEDIINEMNVCIESIVKLSQLLNKEKVSKNEIILQRSWLIHWSLIIIFHFFMYVIYVKNTYPKNNSFSMLQDWFIDEKNLSILNLICPHIIRYYCVYAIFYRNRKDHFELILNTLNFIKSKYNDSFTSLLISIFTDYDFNMAQTCIATIGTLCERDVFLYKLKPYIEEHCRFIIFETYCRIHKSINIDMISSKVNLTREQAEKWIVNLIRNAKLDAKINSEKNCIEISTPPPNLYQQVIDKTQNLIMRSNFIVQVLNRSSNDDQQQIQKNLRFKNKNEKNLKNNKRNKNFNHMYHINNKIVAPDT
The following text describes a protein:
Function:
May transfer the 4'-phosphopantetheine moiety from coenzyme A (CoA) to a serine residue of a carrier protein domain.
Sequence:
MTTYIAYGNINQPFSLESLPDELIPENLYQIETDSSRVFQRHQCRRLAHLLLFQLLKIAGKSTALLSQIHRTESGRPYFLDERIDFNISHSGDWVAVILDIRNEEKSAVGIDIEFPKIRNFTALMEHIAPKEEIDWFHHQQDSLNAFYRCWCLREAVLKSQGFGIVKLSNVRHFPEQQKIFSDYCPQGQLWFTDELPIYLAAFVNHQEKLPHFYEWNRESLQIKELEKYVLYEVN
The following text describes a protein:
Function:
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
Sequence:
MASFNILHGFTEALVRGMRSSFLTDADYHHLTQCETLDDVRLNLSETDYANALEDMNSLIPTGLQKAAVEKVRFVLLVTEFQYLRTQAVEPLSTFLDFITYEYMIENVMLLLKGTLSGRDINELIAQCHPLGMFKESTMRSIPTFESSPRGYQDLYQTVLVDTPVGPYFSLFLQETAMRGEVSNVLEEVEIEIIKSSLIKYWIEDFARFVDSLGGETATIMGDLLKVRADTNAINITLNSFGTPLNEPAMRASDRKRLYPSVGHLYPAGTSMLADVSDEDELGRVLELFPLYSSIWNVHAAGGDGKSIDDAFYERDVQMLELAFEGQMHFGAFYAYVKLKEQEIRNLVWVSECILQQQKEEINKFVPVFSFHAPWRAGSKSRR
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLYACDDVTGNIVSTGVYFAPLPTFIQILKQKSTMGFQSLPYVVSMFSALLWMYYAFIKKGDTFLLITINALGSLVEFIYIIIFLVYATPSVKKHTIMVVSATMVLCIVISLGSFYFLEGVSRALVVGWICVGVSVCVFAAPLTIVFQVVKTKSIDFMPFPLSCFLTLSAMMWFAYGMFTSDLCVTVPNVLGFVLGIIQMSVYKYYKQNRRKVPGILEAKEKEHIININTSNSEVYPVDSGQSSATETEEEKNTTKGGGEVIEHNKCRPRATVDVEPCGVEVVTISVKPVLIICTA
The following text describes a protein:
Function:
Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSALLKPLDNRLFWPAVAIGGLLILAFVLYLQHVRGFAPCSLCIFIRLDVLGLVLAGIVGSLAPRSRIAGGIAALGMLAASLGGIYHAWSLVAEEKLAAQGMGSCKMFMGFPEWIPLDTWLPQVFQPEGLCGEVVWTLLGQSMAVWSLALFVFCLLVLAAKLAFGRRTA
The following text describes a protein:
Function:
Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MTPRKKLEGLVAATVTPMTPDGRINLSVIHQYVDYLVSEQNVKNIFVNGTTGEGLSLSIQERKQLAEEWMCQGKGKLDHVIIHVGALSLLESQELARHAAAIGASGIAVIAPSFFKPTNKDELLGFLQKVASEAPTVPFYYYHIPAMTGVKIRVEELLDGIREQIPTFQGVKFSDTDLLDLAQCINKKEREQFVFLYGVDEQLLSALAIGANGAVGSTYNYLGRKTNLMLQAFAKPDLALARKYQFLTGEFLSFVIKLGFGVAQTKAVMTSISGIPMGPPRLPLVGASEEFIAKAKAKLESIVWPDGD
The following text describes a protein:
Function:
Acts as a positive transcriptional regulator of the molybdopterin biosynthesis moa1 locus, promoting the expression of the moaA1B1C1D1 genes. Binds directly to the moaA1 promoter.
Sequence:
MGQRPFSPNHRSGVLNATTAGAVQFNVLGPLELNLRGTKLPLGTPKQRAVLAMLLLSRNQVVAADALVQAIWEKSPPARARRTVHTYICNLRRTLSDAGVDSRNILVSEPPGYRLLIGDRQQCDLDRFVAAKESGLRASAKGYFSEAIRYLDSALQNWRGPVLGDLRSFMFVQMFSRALTEDELLVHTKLAEAAIACGRADVVIPKLERLVAMHPYRESLWKQLMLGYYVNEYQSAAIDAYHRLKSTLAEELGVEPAPTIRALYHKILRQLPMDDLVGRVTRGRVDLRGGNGAKVEELTESDKDLLPIGLA
The following text describes a protein:
Function:
Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
Sequence:
MDAKLASSQLRIYKQMCPFLGRTSPLSLRKMSTHSVMGVTRLRLRAQACPVLGPLLSLDPNPITQLNNRQPHHRHYAKPANMDIAIKNIYKKPIQSQQCPSAAKDDDYHHHLINKRDDHHHHHPNQELFDYEKFYNNELEKKHQDKSYRYFNNINRLAAKFPIAHTAEPKEEVTVWCSNDYLGMSKHPLVLESMKNTLTKYGAGAGGTRNIAGNAALHLSLESTLADLHRKESALVFSSCYVANDATLSTLGSKLPGCVIFSDSSNHASMIQGIKHSRAEKVIFQHNDLVDLEAKLASYPKDRPKIIAFESVYSMCGSVGPIEAICDLAEKYGAITFLDEVHAIGMYGPRGAGVAEHCDFEAQAKGGKKGSVMDRIDIITATLGKAYGVVGGYIAGSSSLVDMVRSYAPGFIFTTSLPPAIVSGALTAVKYQMNNLDDRRLQQLNTIELKDKLVNQFDLPVMNNPSHIVPILIGDPAKAKMASDLLLSKHSIYVQSINYPTVPKGEERLRITPTPGHTVEQQAKLIEALDSIWKELNLNRTEDWKRLGGRAGVGVPEPTAGNPQREERIWSDQQLCLVDGTHPIRIGRHQDDPHLDPAKDYRPNNQQSYLLSPQDQGPASFESELNFSHTLDRAPAANSVPVQNSFAKDQQAVV
The following text describes a protein:
Function:
Component of the intraflagellar transport complex B (IFT-B) involved in flagellar assembly (Probable).
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, flagellum basal body. Note=Localizes to the cytoplasmic and membrane-bound portions of each of the eight axonemes, localizing particularly at the flagellar pores and at the distal flagellar tips. Localizes to the basal bodies.
Sequence:
MSYHELQHFTLLMTQIGFPRPISIDTFRKPDFFLVAEILHYITTVVAPSNAIAMDIATQEDRVYFITTVVNVLQTTLHLKLDSKKIYAAGPEAVRELRKIVQEVATYIGAAATSTDKGTSSAASVDLTLHSNALCVASSKIVEASTKLLTQLRLHVDDLYQRMQQAMSSQPDAASLSAAVQQRIKNLAAECNTLQEEVTTNKREKAKLEEQITQKKQSITHTMDRLDAIRSTKPPFLAELEALEADLSKLHLEYARKFRSLLFLEGQLRANDVREQQRVIEREKNLRALQENALKEELNNMYGGVDARSSTSHLDDEFVETPMPHVMDMHQPKPVQDFVPSKAAPINTNAEIPDDESYSYSYEEEEEEEQVISSANPMQQARAPETHSNGEKHRGLDELSHKSNENADNEEYSYEYSDIGGEELDPDNIEF
The following text describes a protein:
Function:
Putative anti-apoptotic factor involved in the regulation of tapetal programmed cell death (PCD) and degeneration during anther development. Interacts directly with the DEAD-box ATP-dependent RNA helicases AIP1 and AIP2 that form dimers and bind the promoter region of the cysteine protease CP1 involved in tapetum PCD.
Subcellular Localization:
Nucleus.
Sequence:
MAASDADAAEVERLYELGERLSSAKDKSQHAADYEAIISAVKGQSVKAKQLAAQLIPRFFRSFPALAPRAMEAMFDLVDMEELATRIQAIRGFPLLAKDAEFVSKIADILGQLLASEENVERDAVHKALMSLIRQDVKSSLQPLFKHVESGSEIREKVICFLKDKVFPVKAELLKPQAEMERYITDLIKKSVLDVTGLEFKLFMDFLRSLSIFGDSAPRESFQELIEIIQAQADLDAQFNVSDIDHIERWTSCMYMALPIFMRGGSSSKFLNYFVKQIVPVFDKIPEEKKLDLLKTVAASSPYATAQDARQLLPPVVQLLKKYMPGKKVEDINHNYVECLMYIFHHLAHKTPNTTNSLCGYKIVTGQPSDRLGEDFSEHYKDFTERLTGTEETVRAVSKRLTQGMADFNKAISSAKTEEEKTKIKSDQQKSTMTMRAYNNILAMAQPLRAKSPLFIGDKKITLSWMEQPKKPAPTTTGGKRSQPATNGNTPASKKGRGEGAARNQLVNRAFEGLSRGGRGSGRGRGRGGRGRGWGYR
The following text describes a protein:
Function:
May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.
Subcellular Localization:
Cell projection, cilium, photoreceptor outer segment. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.
Sequence:
MMLLDVKHILWLICVCSAYSQDDSVRRMRVVRSSSRVHGALAQSVVLPCRFLVLPPLPGSSVITHSDHLRIKWTKLQSHGEAVAVVAQNGIVKMGQEYMGRVSVPSRPEDQGDASLTISRLRASDAGVYRCEVMHGIEDTQDSITLDVSGVVFHYRANTSRYSLNFTQAQQACADVDSSIATPEQLYSAYEDGFEQCDAGWMADQTVRYPIIRPRDGCHGDKWMKPGVKSYDVRNAYEKYDVYCYVGKLQGEVFFIDQKLSLDEARSACVGQDSVLASPGHLHAAWRDGMDQCDFGWLSDGSARYPVSVPRLQCGRGQLGVRTMYRNADRTGYPLPTMKLGAYCFRGRDPTTAPTAGPTTPTVPSDVLKISSLEVMSSAPTDDTIEEPPSMFSASMAPRDKPTPEAYPTIVTTQTGGILDTPSPTFGDYDDNSNLMVQGAPDLSLQGTVGSTTMVTPSYYDSIFSIKLPPQPTKGVKNPLDTPHGEYSSAEGSISGDTETPESVIPTSPVLVTTLQVDPDQPKVVYKEDGSTENITEGVVFAESSMGTPGLGEVIVHGSQSEVSKNVSFPIDISLLIVDIKDTNQSVESVLDFLGEPRGITDVLTSSENEPPLGSGDLEIYPSASVTVTPEVSFINGKHELTLQPVAEQEARGDQFDTVTPPIEEIIPDDEIVILMSEFEGVVSSPKTDESGLTTRSPVEPHFTTKISKPDLGSGDLEIYSSASVTITPEVSFINGKHELTLKPDVEHEARGDQFDTATPPMEEIIPDDEIVIVLAEAEGLTSSYKTDESGLTTRSPVEPYFTTKISESTTMSELPIFSTKSPSQEITPQAISFSTSINEESSGMRPTDDEEELTTLEGSADDLQSATASTDPDMVATDETEIGGTEKPTQAYGVHCSTQGPITTPETSQTTASSPVEKEIKPERDDFEGSTSAEEESSGQDMYSREEPKQPILSPTLSVPSHSFTTSSTSTHPKDPREPASLLLPSAEPAVNVVSTLQTRVIPEEKDQSRSTTKSPLLVPEFEKDVSTVFAISGDSGSGDHPTEALTKQPFIVTTLPSLFIQQTVETSVDANEPTKAFEGSAEDTTPLSFTTARTETKFTTQRSDARILPTNSLRAIMSSSQETVLIQKTHSEETTTLVVPSETTEETMLPSKFGFSTEEPLISTSVHSSGPITIADTNLSISESVQDITSTTSTTEDMIPTPKATSTSSFEETVVDYEDVQGASVVERQPPIREEFTTKKPEVWTDSSYTVESHVVDLQDHALCSVSVCENGGTCFSSRKGNVCVCMPGFSGERCENDVDECQSNPCRNGATCIDGINSFKCVCLPSYSGSLCEQDTEVCDFGWQKFQSHCYKYFTHRRTWEAAERECRLQGGHLTSVLSHEEQLFVNRLGHDYQWIGLNDKMFDNDFRWTDGHPMQFENWRDGQPDSFFSTGEDCVVMIWHESGQWNDVPCNYHLTFTCKKGTVSCGQPPLIKDAQVYGSMKPRYEINSLVRYHCKEGFIQRHVPTIRCREDGQWDKPKITCLNPSTFQKMYAHKYQNNNYYNSSKRRFSESQYRHRWSKTAEELKH
The following text describes a protein:
Function:
Catalyzes the oxidation of 2-deoxy-scyllo-inosamine (DOIA) with NAD(+) or NADP(+), forming 3-amino-2,3-dideoxy-scyllo-inosose (amino-DOI).
Sequence:
MKAAVIESVGRAVVTEVPDPTPGPREVVVEVAACGLCGTDLHILQGEFAPKLPIVPGHEFAGAVVGVGAQVTEVAVGDQVAVDPSLYCYECRYCRTGHNNLCERWAAIGVTTAGGAAQYAVAPVANCVKLPEHVRTQDAALIEPLSCAVRGYDVLQSRLGAHVLIYGSGTMGLMMLELAKRTGAASVDMVDLNPARLETARGLGVSASAATPDELDRPQGWDLVIDATGNAAAIQDGLDRVAKAGTFLQFGVADYATRVQIDPYRIYNQEITITGSMAVLHSYERAAELFANGVLDPDVFISDRIELARYPQALEQFAAGVGRKIVVVP
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MVENIIGTTLDSAIILCQNLVHTRHCRSVGYGQKSLIYHCKTCSKNESACLCALCFNGSDHKGHDYSITESSNFTCDCGDESQWKEEGFCRLHGKEFTGNLRLLLPDKYREFPEKMTQCIDVYVFELIRNNITEVEKIGDIILKLMRVDLFYLIIAELLTKQFSPSSSVLIEQLHQQNITYHEFLYEKMFTTPKPPTTLIKILTSFQTDLTLIHFDHEIIYKLFIYSLEFSQHSLNEVFCNTFIFRSYKDNNNKYLFFNKERYLQFISITQSVLDGYVSQNTTTTIQQVQNVYDFLWDVFLYCPNEIQNAPFDKSCVIKTAVFLATLSNRFETLPCSKIHEQQNQSRQEILKKIYCLYLITSRLIPNINIQYLYAAYNEVLAILIQHIQKYFKEVPSIVLDGDNIDVRIHQTNQPCSPMGFILPFFLSIYLRSIKEGINPLIQKEDAKLILQYCLLSIKFRQDYENKVYIYNDDTVLLFYWYYVSGTNLRTILSDYTMVRVLIPIVGVEYFIKESCVMFEMIEYSQSIKHYSIHKISKKKEIVVNYLTLLIQIDRRFELLNDLSDEDMLKLIISHHIISGNTKPNEISKKVMIRNFNTYDVFDLVYDKDNKQLRKYYLEEIDPLTPLLKLSEKEVLINTCLLQPQSPLPHRYQFNSLRKDEPHKILFQSVLLYSLIKDIIELRLEDISPLIIMLILECNDVVEELNKTITTRRYILSEPNHEMERLMRSDEEMFQINEYMKYFGREMGMKEKELFEMNEVVKEIGNEFEVEYENYKKEQRKNIKHHKDKQAQIKKRMINQQNKILLKDKEELQELVKEEEEEICVICQQKKNDIVGFFTCFSENKKVETIRKMHNGIKVKCNVNGCQHTVHYSCYQHYKRNICPICKYQINHFLPHQNEFKKEESTISEGKEITRKEVLRNCISNEFYDEKSKEIDILENVIDCLYGTIVSLQCSSELNYLYKETDRQIILSLLEIARFIFCETELFQDIHQMHYDIEDYYQQCKNPLKIYLFSLISQSNTIERIAWTSQARNCACIAKQLGLCHDEFVCIDDNIHYQNMILPTNIQKQLQECLSIKQLTEQLTCVLNDQIKLLNEIIHIKEINVYLRVYEMMGFIDELSFNSLPDIKQPIFDFKLQKYFKDFVGQFAEQKCSVCNELPKEYMKCSYCLNCGAFICDNQECFISHKLKKESPDLLYIYLRNGRICVHINSTLTASSCIYFNKYTEPFEQSQLKHSEFILNELKLQEFLQHYIRGDVIENPMFK
The following text describes a protein:
Function:
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Nucleus.
Sequence:
MRPPSLLLPPLLLLLCRPVVQSRGLQCGSFPGPCANGGTCLSPPQGQGTCQCAPGFLGETCQFPDPCQDAQLCQNGGSCQALLPTLPGSTSPPSPLTPSFFCTCPFGFTGERCQAQVKDPCSSFCSKMGRCHIEASGRPRCTCMPGWTGEQCQHRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHTCEHDVNECFLNPGPCPKGTSCYNTLGSFQCLCPVGRDGPRCELQPGPCPPRGCLNGGTCQLVPGRDSTFHLCLCPPGFTGASCEVNPDDCVGHQCQNGGICQDGLGTHTCLCPEAWTGWDCSEDVDECEAQGVPRCRNGGTCQNSAGSFHCVCVSGWGGTDCEENLDDCAAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHMEDMCLSQPCHGEAQCSTNPLTGSTLCLCQPGYTGPTCHQDLDECQMAQQGPSPCEHGGSCLNTPGSFECLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGRLCEVETDECASAPCLNQADCHDLPNGFRCVCQPGFTGPRCEEDINECRSSPCANGGQCQDQPGSFHCECLPGFEGPRCQTEVDECLSSPCPSGASCLDLPGAFLCLCPSGFTGHLCESPLCAPNLCQSKQKCQDQEDKAHCLCPDGSPGCAPAEDNCTCHHGHCQRSSCVCDVGWTGPECDAELGGCISTPCAHGGTCHPQPFGYNCTCPTGYTGPTCREEVTACHSAPCLNGGSCSPSPGGYSCTCPPSHTGLHCQTSIDHCASAPCLNGGTCVNRPGAPSCLCAPGFQGPRCEGRVRPSCADSPCRNRATCQDGPQGPRCLCPPGYTGGSCQTLMDFCAQKPCPRNSRCLQTGPSYQCLCLQGWTGPLCNLPLSSCQKAALSQGAEVSSLCQNGGICVDNGPSYFCHCSPGFQGSMCQDRVHPCESRPCQHGATCVAQPNGYLCQCAPGYSGQNCSEEPDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDRPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCQSQPCSHGGSCETTAGPPPGYTCHCPQGFEGPTCSHRAPSCGLHHCHHGGLCLPSPKPGFPPRCACLNGYGGPDCLTPPTPPGCGPPSPCLHNGSCSETPGLGGPGFRCSCPPSSPGPRCQRPGAKGCEGRGGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPTCTPAYDQYCRDHFHNGHCEKGCNTAECGWDGGDCRPEDGGSEWGPSLALLVVSPATLDQQLLALARALSLTLRVGLWVRKDSDGRDMVYPYPGAQAEEELGGTPDPSHQERAAPQTQPVGKETDSLSTGFVVVMGVDLSRCGPDHPASRCPWDPGLLLRFLAAMAAVGALEPLLPGPLLAAHPRAGTAPPANQLPWPVLCSPVAGVLLLALGALLVLQLIRRRRREHGALWLPPGFTRKPRSQAVPRRRRPPLGEDSIGLKALKPEAEVDEDGVVMCSGPEEGEEVGQAEEMASPSKCQLWPLSADCQELPQAAMLTPPQDSEVDIPDVDTRGPDGVTPLMSAVCCGGVESRTYQETWLGSPEPWEPLLGGGACPQVHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHTAVAADAREVCQLLLRSRQTAVDARTEDGTTALMLAARLAVEDLVEELIAARADVGARDKWGKTALHWAAAVNNSRAARSLLQAGADKDAQDGREQTPLFLAAREGAVEVAQLLLGQGAARGLRDQAGLTPGDIARQRNHWDLLTLLEGAGPPEARHKATPGRGVGTFQRARTASGSVLPRGGGALPRCRTLSAGACPQARTLSVDLAAHGGGAYSHGRSLSKGGAGGGPPLRGRRFSAGMRGPRPHPAIVRGRSGVTAGSGGVASGDHWPCDWVALDACGPASSTPIPPPCLTPSPERASPQVAWGPPAHQVIPLNAGGEGQK