lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MSPASPTFFCIGLCVLQVIQTQSGPLPKPSLQAQPSSLVPLGQSVILRCQGPPDVDLYRLEKLKPEKYEDQDFLFIPTMERSNAGRYRCSYQNGSHWSLPSDQLELIATGVYAKPSLSAHPSSAVPQGRDVTLKCQSPYSFDEFVLYKEGDTGSYKRPEKWYRANFPIITVTAAHSGTYRCYSFSSSSPYLWSAPSDPLVLVVTGLSATPSQVPTEESFPVTESSRRPSILPTNKISTTEKPMNITASPEGLSPPFGFAHQHYAKGNLVRICLGATIIIILLGLLAEDWHSRKKCLQHRMRALQRPLPPLPLA
The following text describes a protein:
Function:
Involved in disease resistance. Required for NPR1/NH1-mediated immunity to the bacterial blight pathogen Xanthomomas oryzae pv. oryzae (Xoo). Required for the benzothiadiazole (BTH)-induced immune response. Probably regulated by the transcription factor TGA2.1.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MSMACYYLAAAAAGLALLLLHAPLTDAQTLVPLCGDSGNYTEHGTYHANIQYLATSLPSYASSSPSLFASGSSGTVPDAIYALALCRGDTNSSSCATCVAAAIQSAQELCPLVKTVIVYDDTCILRFANDAFPISPTSNSQGMVVAWKAQNVSAAVAPAFEAAVVRLINTTADYAATDSVRRFGTGEEAFDETTFPKIYSLAQCTPDMAATACRSCLEDIVGRMVSGNLIGRMGGRVLGVRCNLWFEVYPFFSGRSLLQLPGPSPSPAPPVTAAGERSKNKRSAILAISMPTIALVLATIAAWFCSTSWRRRRLARKTLRPKSSEDEMQSFASLVLDLQTLRTATDNFSEHKRLGEGGFGVVYKGDLPEGQEIAVKRLAQTSRQGIEELKTELLLVAKLNHNNLVRLIGVCLEENEKILAYEYMPNRSLDTILFDAERIKELDWGQRFKIINGIARGLQYLHEDSQLKIVHRDLKASNVLLDSAYNPKISDFGLAKIFERDQSQVITHRIAGTYGYMSPEYAMRGQYSMKLDVYSFGVLVLEIITGRRNFGSYGSDHVVDLIYVTWEHWTSDKAIELIDPSLGNHYPVDKVLKCIHIGLLCVQPKPADRPLMSAVNAMLSSTGTVRLPCLSRPSFWVQEIGATAS
The following text describes a protein:
Function:
Acts as a chaperone for the L4 ribosomal subunit encoded by rpl4A and rpl4B, required for hierarchical ribosome assembly. Shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.
Subcellular Localization:
Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Distributed throughout the cell but is enriched in the nucleus.
Sequence:
MSVTDAELLEIREKLVKDETSEALILAKKAADKSPKEDGRAFELLGEVYAELADVKKARSAFKEAVSRSKNLTNDQGYEKYLWLAQINDNGSKALKLYQKGVTILERLLIDKGEDADLKKKIQGAYCSIAELFMTDLCMQPDAEENCELYTKLALQIDATNAEALQTLASMRISQQKIEEAKDALSKCLQSISRAATEDSVDLPTYAVRTSIVRLLIEVEMHEEAHQLLVYLQKEDDQILDIWYLLGWNCYVEAQNLQEQGNGSEEEIKELLMNAKFYFISALGVYQKIGWDDEGIKSHIQELLEILNGLGVPNMDEENEEAEWETSENEEEMDED
The following text describes a protein:
Function:
Mediates the incorporation of phosphate into alpha-glucan, mostly at the C-6 position of glucose units.
Miscellaneous:
MISCELLANEOUS: The reaction takes place in three steps, mediated by a phosphocarrier histidine residue located on the surface of the central domain. The two first partial reactions are catalyzed at an active site located on the C-terminal domain, and the third partial reaction is catalyzed at an active site located on the N-terminal domain. For catalytic turnover, the central domain swivels from the concave surface of the C-terminal domain to that of the B-terminal domain (By similarity).
Domain:
The N-terminal domain contains the alpha-glucan binding site, the central domain the pyrophosphate/phosphate carrier histidine, and the C-terminal domain the ATP binding site.
Sequence:
MATSKSQQFQLIEGMELQITVTGLPNGSSVRAEFHLKNCTRAWILHWGCIYQGNNHWYIPSEHSSKQGALQTTFVKSGDAYVVILELRDPRVRAIEFVLKDGSHNRWLRQHNGNFRVEIPWNDLHAHHRIPKTLIERRAHKIWDRKGRPQSSAREQQIDYDNAVRELHAELARGISLDELQANSTVPVEKEETSEPHHTMIQSYRRKHDVQKWLQKYTEPINRSGSVKSSALAELSKRSVGQENLVSQKSFHVRNYEITVLQRDVKGDCRLWIATNMAGPTVLHWGVAKSSAGEWLIPPPDVLPEKSKFVHGACQTQFTDMSSREHSYQFIDINLKRGGFVGIQFVIWSGGYWVNNNGANFVVNLKSADSTSGKLDVDEKYVLKWLLDEISEREKEAERSLMHRFNIATELTERCKDEGEGGCIGIMVWMRFMATRHLTWNKNYNVKPREISEALERFTNLMEKIYLQQPNKREIVRLTMALVGRGGQGDVGQRIRDEILVIQRNNHCKSGMMEEWHQKLHNNSSADDVIICEALLNYVRSDFRIDAYWQTLQTNGLTKERLASYDRPIVSEPRFRSDSKEGLIRDLTMYLKTLKAVHSGADLESAIDTFLSPSKGHHVFAVNGLSPKLQDLLNLVKRLVREENTEPLIEKLVDARIQLHPALRAPRTRAKDLLFLDIALESCFKTTIEKRLISLNFNNPPEIIYVICVVLENLCLSIVNNEEIIFCTKDWYRVSEAYRPHDVQWALQTKAVLDRLQLVLADRCQHYFTIIQPTAKYLGQLLRVDKHGIDVFTEEVIRAGPGAVLSTLVNRFDPSLRKIANLGCWQVISSADAYGFVVCVNELIVVQNKFYSKPTVIIASKVTGEEEIPAGVVAVLTPSMIDVLSHVSIRARNSKICFATCFDQNVLSNLKSKEGRAISIHTKSTGLVISDGNNSDVSVRHIFISSVPRGVISKGKKFCGHYVISSKEFTDERVGSKSYNIKFLRERVPSWIKIPTSAALPFGTFENILSDDSNKDVARRISVLKDSLNRGDLTKLKSIQEAILQMSAPMALRNELITKLRSERMPYLGDESGWNRSWVAIKKVWASKWNERAYVSCKKNKLDHDAVCMAVLIQEVICGDYAFVIHTNNPVSGDSSEIYTEIVKGLGETLVGAYPGRAMSFITKKTNLKSPTVISYPSKRIGLYSKPSIIFRSDSNNEDLEGNAGAGLYDSVIMDEAEEVVVDYSREPLIMDKSFRVRLFSAIAEAGNVIESIYGCPQDIEGVVKGGHIYIVQARPQV
The following text describes a protein:
Function:
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MIASKETKEKIRNFIGGFASGAASTLAGHPFDTLKVRLQTEGSTGRFRGLAHCFTTTIKEEGFFALYKGVTPPLLGMSIINSCMFGAMNIVKSKIHTDKSTPISLGEIMVSGAITGWIVSFVACPIETVKSKLQVQYTGVKLYNGPIDCIKKIGIRGLYKALIPTGFQRNSLYAYFGCYELAQRYLRREDGSMTMGRSFIAGGIAGTGFWLTNFPFDVIRSRIMTMPYNESPPRYKGMIDCAKHIYRVDGLKGFWKGFSPCLLRTFPANGATFVAYECVMKFFPM
The following text describes a protein:
Function:
May play a role in membrane trafficking.
Miscellaneous:
MISCELLANEOUS: Present with 6140 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=More enriched in the cortical endoplasmic reticulum (ER) that is closely apposed to the cell membrane than in the perinuclear ER or internal ER tubules that connect the nucleus to the cortical ER.
Domain:
The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers; The C-terminal C2 domain shows Ca(2+)-dependent phospholipid binding. It binds to phosphatidylserine, phosphatidylinositol and various phosphoinositides. The other C2 domains do not retain all 5 conserved Asp residues found in calcium-binding C2 domains.
Sequence:
MAKEDTGVTAPKKPETAQVANINGIDKLEPPKTKEETESSKSVSSEKAAHASDESFKRSIHEASYVGWKQIGGWEDKDELTLDDELMDMTRETFLDNIIPDSLYGDWYHSVAIFFIGGVASFALGHYKFSMGSAFFVIVITSLLYRTSAKKYRGSIRELVQKEFTVQKVENDYESLEWLNAFLDKYWPILEPSVSQLIVQQANEQMATNEAIPKFITQLWIDELTLGVKPPRVDLVKTFQNTASDVVVMDWGISFTPHDLCDMSAKQVRNYVNELAVVKAKIFGITIPVSVSDIAFKAHARVKFKLMTPFPHVETVNIQLLKVPDFDFVATLFGRSIFNWEILAIPGLMTLIQKMAKKYMGPILLPPFSLQLNIPQLLSGSNLSIGILEITVKNAKGLKRTSSILNESIDPYLSFEFNDISIAKTRTVRDTLNPVWDETLYVLLNSFTDPLTISVYDKRAKLKDKVLGRIQYNLNTLHDKTTQRNLKAQFLRNSKPVGELTFDLRFFPTLEEKKLPDGSVEELPDLNTGIAKVVVEEGSRFAEEEQKVTAYVEVYLNAKLVLTTGKATDTGTLKWNSDYEAVIADRRKTRYKFVVKDGKGEEIGSTIQTLNDLIDRSQVNKNLIPLKNQKGDIKITTYWRPVRLEIGSNSVAYTPPIGAIRVFIEKANDLRNLEKFGTIDPYCKVLVNGLSKGRTDFKSQTLNPVWNQVIYVAVTSPNQRITLQCMDVETVNKDRSLGEFNVNVQDLFKKDENDKYEETIDEKAKVGRLVMPKKKPKGTITYYTSFYPALPVLTLEEIQDLDKVNKKKKALELRKSAIDEKKISKEDKAKFDQEWNEVKELEDMYSNRQKLDLPELLQYNQGVLAVTVLNGELPDSGLYVQAFFDDNGHPRFVSPRIPSRIVKNGWSGDVIIKELDKSITTFRVAKNKNYNRVEKCVCEVELPTQELVKNCYYKPSILHLSGEGSAKLMLQISWFPIDTKQLPANDLITNSGDLTIMSRSAENLIASDLNGYSDPYLKYYINNEEDCAYKTKVVKKTLNPKWNDEGTIQINNRLNDVLRIKVMDWDSTSADDTIGTAEIPLNKVKVEGTTELDVPVEGLENAGQDGGMLHLAFSFKPRYTISVSKREKKVGDIASKGLGTGLKAGTTVIGGGVGAIGKIKKGVFGGLGSLTNHKKNHEMGEEETKF
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MGEDKRQVTTVEEEAAAEAAAKSPRKSPRLTAAVVPLAAVPLAAVSPESSESPSTQLDSSESTCSDDSQEHQHMFMTDEELAAIANNFKTAKEHPMCQHDDCKVTWKGASDGGGEDAGMMLCTECGCHFCTGPVGDMLNPRGHAYWHAHEAMHRVALWYDDPYKAYCFDCEEGLTLGGNSSQDKDAWAVVAKNGKDQWGSEDVGGHASGVAYVYGDGYVIRGILNLGSSCYMNASLQCLLALRKLRRMILGLDAWLGFTGHYLKELFVETGSANDATCLLNPRMLLDCVGGSGQQFKGNEMEDTYEFLVSLRNALDKEVKELNDLNCVQGGAVLPEFGESIFRVQMCQTISCKSCPNNSVQQIELYDLQAPVALPSKDPLARSVVSSPKIESHMSPRNICKKLFQETQKSDGEKLQTIAEGCELGDGAMEKKPEPLQVDSTEMKDVVDDRLQTHENDGPREIVEVSIKALDFIPNLFDGIEGVEIADSRNPKDIVPPLFTTEDKGKAQSSDIIPPIVSTEDKGKAKSCDIIPPLVITEDMGKAQSSDIIHDVAEHMNSLSSIEDCLALLLIEQPVEWTCENCSNVAELRRTNSSKNGEQMMGSTNVNTTVGGDQTEQADRKTCPSEQSVDLNRFSSECTSPSRRPHGLDAQDKVILYEDRTTKGITSETSCDEKDSPSSSTGNKKSESHQGVQEAVLICLPTDKRTNMLVVQDSQDTSTENQGRGKQVKLDDHSVKQVDKDQNEQKNEDGGATQTILLTKLPPVLTIQLKRSAADLSKLVGHVSFNEILHVGPFMDPSCEDKDNSSYRLVGVIEHIGSTLRGGHYIAYVRADRNQQSGSSSWVCANDSSIREVSLQEVLRCEAYILFYERMEEEDD
The following text describes a protein:
Function:
Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Involved in endochondral growth and skeletal development.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cell projection, cilium membrane. Note=EVC2 is required for the localization of EVC at the base of primary cilia. The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner.
Sequence:
MARGGAACKSDARLLLGRDALRPAPALLAPAVLLGAALGLGLGLWLGCRAGRQRTRHQKDDTQNLLKNLESNAQTPSETGSPSRRRKREVQMSKDKEAVDECEPPSNSNITAFALKAKVIYPINQKFRPLADGSSNPSLHENLKQAVLPHQPVEASPSSSLGSLSQGEKDDCSSSSSVHSATSDDRFLSRTFLRVNAFPEVLACESVDVDLCIYSLHLKDLLHLDTALRQEKHMMFIQIFKMCLLDLLPKKKSDDELYQKILSKQEKDLEELEKGLQVKLSNTEMSGAGDSEYITLADVEKKEREYSEQLIDNMEAFWKQMANIQHFLVDQFKCSSSKARQLMMTLTERMIAAEGLLCDSQELQALDALERTMGRAHMAKVIEFLKLQVQEETRCRLAAISHGLELLAGEGKLSGRQKEELLTQQHKAFWQEAERFSREFVQRGKDLVTASLAHQVEGTAKLTLAQEEEQRSFLAEAQPTADPEKFLEAFHEVLERQRLMQCDLEEEENVRATEAVVALCQELYFSTVDTFQKFVDALFLQTLPGMTGLPPEECDYLRQEVQENAAWQLGKSNRFRRQQWKLFQELLEQDQQVWMEECALSSVLQTHLREDHEGTIRGVLGRLGGLTEESTRCVLQGHDLLLRSALRRLALRGNALATLTQMRLSGKKHLLQELREQRALEQGSSQCLDEHQWQLLRALEARVLEEASRLEEEAQQTRLQLQQRLLAEAQEVGQLLQQHMECAIGQALLVHARNAATKSRAKDRDDFKRTLMEAAVESVYVTSAGVSRLVQAYYQQIGRIMEDHEERKLQHLKTLQGERMENYKLRKKQELSNPSSGSRTAGGAHETSQAVHQRMLSQQKRFLAQFPVHQQMRLHAQQQQAGVMDLLEAQLETQLQEAEQNFISELAALARVPLAESKLLPAKRGLLEKPLRTKRKKPLPQERGDLGVPNNEDLASGDQTSGSLSSKRLSQQESEAGDSGNSKKMLKRRSNL
The following text describes a protein:
Function:
Lysosomal thiol reductase that can reduce protein disulfide bonds. Facilitates the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing; Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. Also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation.
Subcellular Localization:
Secreted. Lysosome.
Sequence:
MTLSPLLLFLPPLLLLLDVPTAAVQASPLQALDFFGNGPPVNYKTGNLYLRGPLKKSNAPLVNVTLYYEALCGGCRAFLIRELFPTWLLVMEILNVTLVPYGNAQEQNVSGRWEFKCQHGEEECKFNKVEACVLDELDMELAFLTIVCMEEFEDMERSLPLCLQLYAPGLSPDTIMECAMGDRGMQLMHANAQRTDALQPPHEYVPWVTVNGKPLEDQTQLLTLVCQLYQGKKPDVCPPSTSSLRSVCFK
The following text describes a protein:
Function:
Desensitization to alpha-factor pheromone. Is involved in regulating the signaling pathway for responding to mating pheromone.
Miscellaneous:
MISCELLANEOUS: Present with 5980 molecules/cell in log phase SD medium.
Domain:
The fungal-differentiation regulator (Fungal-DR) domain is only found in fungal regulator of G-protein signaling (RGS) proteins that regulate differentiation pathways. It is required for function (By similarity).
Sequence:
MVDKNRTLHELSSKNFSRTPNGLIFTNDLKTVYSIFLICLDLKEKKHSSDTKSFLLTAFTKHFHFTFTYQEAIKAMGQLELKVDMNTTCINVSYNIKPSLARHLLTLFMSSKLLHTPQDRTRGEPKEKVLFQPTPKGVAVLQKYVRDIGLKTMPDILLSSFNSMKLFTFERSSVTDSIIHSDYLIHILFIKMMGAKPNVWSPTNADDPLPCLSSLLEYTNNDDTFTFEKSKPEQGWQAQIGNIDINDLERVSPLAHRFFTNPDSESHTQYYVSNAGIRLFENKTFGTSKKIVIKYTFTTKAIWQWIMDCTDIMHVKEAVSLAALFLKTGLIVPVLLQPSRTDKKKFQISRSSFFTLSKRGWDLVSWTGCKSNNIRAPNGSTIDLDFTLRGHMTVRDEKKTLDDSEGFSQDMLISSSNLNKLDYVLTDPGMRYLFRRHLEKELCVENLDVFIEIKRFLKKMTILKKLIDSKHCDKKSNTSTSKNNIVKTIDSALMKQANECLEMAYHIYSSYIMIGSPYQLNIHHNLRQNISDIMLHPHSPLSEHFPTNLYDPSPASAESAASSISSTEADTLGEPPEVSLKPSKNLSNENCSFKKQGFKHQLKEYKPAPLTLAETHSPNASVENSHTIVRYGMDNTQNDTKSVESFPATLKVLRKLYPLFEIVSNEMYRLMNNDSFQKFTQSDVYKDASALIEIQEKC
The following text describes a protein:
Function:
Involved in acetate metabolism.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.
Sequence:
MSRNIMLIPIGTGVGLTSLSLGMVRALERHGVKVQFFKPISQLRPNDNGPERSTTILSKSPTVNPLEPFDMAHAEALIRADQTDVLMEQIIARAAECASNTETLIVEGLVPTRNHPFADDVNYAIAKAMDADVIFIATPGSDTPTGLMNRLEIAYNSWGGKNNKRLIGAVINKIGAPVDDEGRARPDLSEVFDHQGVQRSDASIMFQLPGKSPLRILGSVPYNLDLVAPRASDLAKHLRARILNAGEMNIRRLRKVTFCARSLPNMVNHIKTDSLLVTSGDRSDVIVSACLAAMNGVKIGALLLTGSYEPEPEILKLCEQAFETGLPVFLIDTNTWQTSLNIQRFDHEVPVDDAVRIDLVQEYVASHIDQTWIESVTKNSPREHRLSPPAFRYKLTELARAAHKTVVLPEGDEPRTIKAAAICAERGIARCVLLGKKDEILRIAAQQDVVLGEGVVIVDPDEVRARYVEPMLELRRSKGLTEVVAKEQLEDNMVLGTMMLAQDEVDGIVSGAVNTTANTIRPPLQLIKTAPGSSLVSSIFFMLMPDQVLVYGDCAINPDPNAEQLADIAIQSAESAKAFGIEPRVAMISYSTGNSGTGSDVDKVREATRIAKEKRPDLVIDGPLQYDAAVMPNVARSKAPNSPVAGQATVFVFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQASQNDAKKS
The following text describes a protein:
Function:
Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
Subcellular Localization:
Cytoplasm.
Sequence:
MFVQLRKMTVKEGFADKVIERFSAEGIIEKQEGLIDVTVLEKNVRRGDEEVVVMIRWESEDHWKQWEKSDAHIAGHKANKGKPKPDYLISTEVSMYHVRAVKQGTYNQ
The following text describes a protein:
Function:
Essential for cell cycle arrest at the G2 stage following DNA damage by X-irradiation or inactivation of DNA ligase.
Miscellaneous:
MISCELLANEOUS: Present with 400 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSGQLVQWKSSPDRVTQSAIKEALHSPLADGDMNEMNVPVDPLENKVNSTNIIEGSPKANPNPVKFMNTSEIFQKSLGLLDESPRHDDELNIEVGDNDRPNANILHNERTPDLDRIANFFKSNRTPGKENLLTKYQSSDLEDTPLMLRKKMTFQTPTDPLEQKTFKKLKSDTGFCYYGEQNDGEENASLEVTEADATFVQMAERSADNYDCALEGIVTPKRYKDELSKSGGMQDERVQKTQIMISAESPNSISSYDKNKITGNGRTTRNVNKVFNNNEDNIGAIEEKNPVKKKSENYSSDDLRERNNQIIQSNESEEINELEKNLNVSGRENDVNNLDIDINSAVSGTPSRNNAEEEMYSSESVNNREPSKKWIFRYSKDKTENNSNRSTQIVNNPRTQEMPLDSISIDTQPLSKSFNTETNNELETQIIVSSLSQGISAQKGPVFHSTGQTEEIKTQIINSPEQNALNATFETPVTLSRINFEPILEVPETSSPSKNTMSKPSNSSPIPKEKDTFNIHEREVETNNVFSNDIQNSSNAATRDDIIIAGSSDFNEQKEITDRIYLQLSGKQISDSGSDETERMSPNELDTKKESTIMSEVELTQELPEVEEQQDLQTSPKKLVVEEETLMEIKKSKGNSLQLHDDNKECNSDKQDGTESLDVALIEHESKGQSSELQKNLMQLFPSESQEIIQNRRTIKRRQKDTIEIGEEEENRSTKTSPTKHLKRNSDLDAASIKREPSCSITIQTGETGSGKDSKEQSYVFPEGIRTADNSFLSKDDIIFGNAVWCQYTWNYKFYPGILLEVDTNQDGCWIYFETGRSLTKDEDIYYLDIRIGDAVTFDGNEYVVVGLECRSHDLNIIRCIRGYDTVHLKKKNASGLLGKRTLIKALSSISLDLSEWAKRAKIILEDNEKNKGDAYRYLRHPIRGRKSMTNVLSPKKHTDDEKDINTHTEVYNNEIESSSEKKEIVKKDSRDALAEHAGAPSLLFSSGEIRTGNVFDKCIFVLTSLFENREELRQTIESQGGTVIESGFSTLFNFTHPLAKSLVNKGNTDNIRELALKLAWKPHSLFADCRFACLITKRHLRSLKYLETLALGWPTLHWKFISACIEKKRIVPHLIYQYLLPSGESFRLSLDSPSKGGIIKSNNIFSFYTQFLRGSNLRDQICGVKKMLNDYIVIVWGRSELDSFVKFAFACLSAGRMLTIDLPNIDVDDTEPLLNALDSLVPRIGSELSNRKLKFLIYANENNGKSQMKLLERLRSQISLKFKKFNYIFHTESKEWLIQTIINEDTGFHDDITDNDIYNTISEVR
The following text describes a protein:
Function:
Regulates the wnt signaling pathway by interacting with dvl2/dsh, which displaces gsk3b from the axnr-gsk3b complex and thus prevents degradation of ctnnb1/beta-catenin.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle.
Sequence:
MSSAGVLTCIPDSGPIFRETSLRPPVPGQETNNFKPEKFTMDSQHLKHKEDFNREAEGCVAHDSRFSRWGRSLNLLLDDQDGATLFRMYLEGEGLGDLLTFWFACNGFRAMDPLEPKTSKTAKAIYRWYVQNSSAVSGRLKPTTRTQVKECVKNHQLNKTVFDQAQQEIQRAMEQEAFTSFLQSDICKEYARGVEDSPTPESPGPGLPTLTEDEEFGGLHHFSSGMGKINRAFSRIPPRNQRSHFRKLEQTYQYFAPAASINDSEISSDALTEDSMSMTDGSVDGIPPYRSKKQREIHRSVSANGKVSLPFVPRTMRPPAEMMPTSPAEFAAKLTIALEKVKKQRDAEEKLEEKLQRLKEEEEIADYDIPSSSHETVPGAALEDDPQSILDDHVSRVLKTPANLSPRSQSPFVQRKGKFQPAFSKGQTSTSCHLRPKVPQGMEATSTLASELRSSVSSQLPRSSRKPEGCTQPHRPEEGTSAAVLTTPLSPEQEAERNHSVLQWVLDSAKLMKKHHRETASVTPCPELKKATHRAASQPAHLFLQDTSMPPLTAPNTLDQLEEARRRLVEDKRVPKLHKSRCVQSTTLKEKGKTAESVPSSGFSTLKLSEEQKTAKKPSSECPGQGLAIVYYFCGERIPYMIRTKEPSLTLQEFKELLSKKGSNKYYFKKESHEFECNAVFQEVSEEDAVLPLFEEKIICKVERAC
The following text describes a protein:
Function:
May be involved in membrane trafficking (By similarity). Acts as a repressor of abiotic stress (e.g. drought and salt) responses by binding specifically to the promoter of THAS1 to regulate its transcription. Binds to membrane lipid ceramides.
Subcellular Localization:
Nucleus membrane; Single-pass membrane protein. Note=Localized in the nucleus membrane of root tips cells.
Domain:
The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.
Sequence:
MGLISGILFGIIFGVALMAGWSRMMTHRSSKRVAKAVDMKLLGSLSRDDLKKICGDNFPQWISFPAFEQVKWLNKLLSKMWPYIAEAATMVIRDSVEPLLEDYRPPGITSLKFSKLTLGNVAPKIEGIRVQSFKEGQVTMDVDLRWGGDPNIVLGVTALVASIPIQLKDLQVFTVARVIFQLADEIPCISAVVVALLAEPKPRIDYTLKAVGGSLTAIPGLSDMIDDTVDTIVKDMLQWPHRIVVPIGGIPVDLSDLELKPQGKLIVTVVKATNLKNKELIGKSDPYATIYIRPVFKYKTKAIENNLNPVWDQTFELIAEDKETQSLTVEVFDKDVGQDERLGLVKLPLSSLEAGVTKELELNLLSSLDTLKVKDKKDRGSITLKVHYHEFNKEEQMAALEDEKKIMEERKRLKEAGVIGSTMDAVGMVGSGLGAGVGMVGTGIGTGVGLVGSGVSSGVGMVGSGFGAVGSGLSKAGRFMGRTITGQSSKRSGSSTPVNTVPENDGAKQQ
The following text describes a protein:
Function:
DNA ligase involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair.
Subcellular Localization:
Nucleus.
Sequence:
MSSERRPELEETAVDPATGSAASRKFSIVQDAVETTIVAPTNHGPSPRFSTLVRNLFEPLVNLSAVVAALRKKPTEAKAHIASQFIKGWVEEVGKDIYPAFRLILPDKDRERAVYGLKEKALGRLWVKVLNLAKDSPDAKALSEWKQGGNESAGNFSKRCYEVLSKRTSLTDYGHMTVDEVNERLDLLADGETDQAKQIEILTYFYKHMNATELKWLVNIILRQMKMNATEKVFFEPWHPDAESLFNVTASLKRVCWELTDPTKRLTSAEAQVSLFACFMPQIAAFPKYSGQDIAGKHFKGRPFYIEEKIDGERMQMHMSEYGNKFHWWSRRSKDFTETYGNSLDDASGSLTKRLRGIINPKVRNCVLDGEMVAYDPATKKIIPFGTLRTANRNEQNDLNLTKPMFMVFDILLLNDKPLVDYTLAERKRTLRTIFARTDNETVGQEGVLEVLPYTEATTAAEIETCMRKIIAESSEGLVIKDPTSVYRVNTRDDSWLKMKPEYMSEFGEKLDVVIIGGYYGSGKRGSILSSYLCGLRADGSDQFWSFFKVGGGLTAGDYQAIRTKTEGKWKRWDKNDKPKNVLLAGPNGDLERPDVWIEPSDSVVVEVKAASVVASDQYKVGLCLRFPRFRALRLDKTWEDGLTISQFAELRQTVEMEAENKELELEDRKRRNAGPGRGAKRLKLANVSSDEDELGTDERPTSVFKATSFAVLSDMSSPRYMSKAAVENLIKKHGGTVFQTVEGPHTIPVADTRTIKVQALTKRVHGVDVIRPNWLLDCINEEKLVALEPRNLLESSAETLALAKTNVDEFGDSYTRPLTYKEMQEVLRFMDQFDLDQTNPPDLMMEVLETNDGAVPKGMLFYGKKVYMSTSNMDTVALETQFRAYDALRCLQFGGANLVTDMKDLVVAVAKTEEEAKELRRVSSEQVFPFRVVSIKWVEESWKNGTVEIEDDYPL
The following text describes a protein:
Function:
Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
Subcellular Localization:
Secreted.
Sequence:
MKLTIAIVLVTLTLFCRPASTEVCPSLLYVLGNLIAGTPSSFEATLEPFSPDEDMKEATSQLKTLVDTLSPKAKDSMLELMMKIIQSPECA
The following text describes a protein:
Function:
Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRRARNGGPGRARRGEAATCKMAAEGDEPLKRWLVPFLLPEECYDQFFLNWDLLHVPCLKILLSKGLGLGIVAGSLLVKLPQVFKILGAKSAEGLSFKSMFLELVALTGTMAYSIIHGFPFSAWGEALFLMVQTVLICFLILHYRRQSLRGTIFLITYALAVTLLLSPVTPPAVITCLQACNMPTVVVGKLLQASTNYRNGHTGQLSAVTVFLLFGGSLARIFTSIQETSDPLMALTFVVSSLCNGLIAGQVLYYWKAGAPQKRKKKKKHQ
The following text describes a protein:
Function:
May play a role in leaf development.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MKPTTNGGLLASQSSSSFSFPRFRGQLPIIFSANNNQKKKNLPNPNVVTLCLHSHSNVSSSQIAVTRRAILVAPPLLAAAASLFLSISSAASAETSAESVALPPVATAPPPPPVEKEEAITSRIYDASVLGEPMAVGKDKKRVWEKLLNARIVYLGEAEQVPTRDDKVLELEIVRNLRKRCIESDRQLSLALEAFPLDLQEQLNQYMDKRMDGEVLKSYVSHWPVQRWQEYEPLLSYCRDNGVKLIACGTPLKVLRTVQAEGIRGLSESERKLYTPPAGSGFISGFTSFSRSSSLNMNPLTQIVPFGPSSYLSAQARVVEDHTMSQVIVQAVADGGGTGMLVVVTGANHVEYGSRGTGLPARISRKIPKKSQLVVLLDPERQFLRKEGESPVADFLWYSAARPCSRNCFDRAEIARVMNAAGRRRDALPQDIQKGLDLGLVSPEILQNFFDLEQYPLISELTQRFQGFRERLLADPKFLNRLAIEEAISITTTLVAQYEKRKENFFEELDYVITDSVRASVVDFFTVWLPAPTLSFISYADETIGPNSIDALRGLLGSIPDNAFQKSLGGQEWTLSLRIASVIIGGLKLAGVGVVSSFAAVGSSNALYAIRKFIKPELGVGEQAKRSPMLKTALVYGGYLGTSSNIRYQIIAGLIEHRISDELSSQPLLVNMISFVVRVANSYFGTQQWIDLARSTGLQTQKSVTTSNQIPEVASQSTVEYSTTEEASMDDLKNQ
The following text describes a protein:
Function:
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). Specific for lipid substrates, inactive towards water soluble inositol phosphates. Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3-kinase (PI3K) signaling and stability (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle. Cytoplasm. Nucleus. Note=Peripheral membrane protein associated with Golgi stacks.
Sequence:
MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSLGPGRPRSPLACDDCSLRSAKSSFSLLAPIRSKDVRSRSYLEGSLLASGALLGADELARYFPDRNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWETRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLLGIKRRISKEIQRQQALQSQNSSTICSVS
The following text describes a protein:
Function:
Mediates influx of magnesium ions.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MKRILLTEYFPEGSQEKSVAHPCQILQKIENKPTEVPELEWLCNKGLIWIDLDSTESEDIDFLARECNFHPLAIEDCINKNQRPKLDEYDSYLFIVLHRFHYDTDKKILRNSEIHIFFNEKFVVTVHQKEEPLIEQLRERCMTQGNPLSRGTDQILYMLFDQTVDSNFPILDKMSEEIVRIESQILVNQDSNQTIAGILFLKRNLTRIRRVLSPQREIVNSLIRRDHNFLTPKIQIYFRDVYDHLNRLYETIDMDRDLLGNTMDAYFSVISQRTNDIVKRLTLISLIFMPLTFLTGFFGMNFTAIPYDSNSFLYFTILFASIIPIGMIYWFRKKHWFKD
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MKFGKKKEKENLENIEKDKDRDKEKEIKEKEKKDKKSKDKKKNQEIEKDNNINNNNNNNNVKKVFGGSLPFLFEEELPTILVQTIDYLQLFGLQTPGIFRENGSLASIQSYRSLYDNDKPVNFPPHEAHVVASLLKAYLRELKVPLCTFEHYDMFIACESIADEKVKVELLKKVIAHLPPFNRKVMKYIFSFLQKVVENSNVNKMTPDALSIVFLPTILRPQANTDLEILQFTVEDSKSTKTLMSSILLNYDEIFEDPNLFQPRTRQARAQTDFVSPPSSQNSTSSSSYLSSKNPISPRSPIGSSPNFTTASILSALPPPPISPILSSNTTNTTLPPPIITSSIDDNNEPSLSPRIITTTTTTTPSPQPTTTTTTHRLPPSNPIPPTPTSNSQSQLYPNLPPPSSDPIIKSTTTPTLNSQSQSQLYPNLPPPLPDKNKCKLLPITPITTNESNTLQPTTPTSTNIPPLSIPPQIGGNSDSNPISPTKNQSQLPILPPKPPSLTLPPKPIPKIPTILEYENNVRQRSNTTMV