lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable transcriptional regulator considered as cadastral protein that acts indirectly to prevent the B class homeotic proteins APETALA3 and perhaps PISTILLATA from acting in the gynoecial whorl. Principal function is to balance cell proliferation in the third and fourth whorls of developing flowers thereby maintaining the boundary between stamens and carpels. May fulfill this role by repressing genes implicated in cell division. Plays equally a role in the determinacy of the floral meristem. Is also required for normal ovule development.
Miscellaneous:
MISCELLANEOUS: Mutations in SUP cause the ectopic expression of APETALA3 leading to the development of extra stamens at the expense of the central carpels of the flower.
Subcellular Localization:
Nucleus.
Domain:
Contains two overlapping leucine-zipper-like motifs at the C-terminal region, which might serve as a site for protein-protein interaction. In this domain, a slightly degenerated ERF-associated amphiphilic repression (EAR) motif seems to be involved in the activity of transcriptional repression.
Sequence:
MERSNSIELRNSFYGRARTSPWSYGDYDNCQQDHDYLLGFSWPPRSYTCSFCKREFRSAQALGGHMNVHRRDRARLRLQQSPSSSSTPSPPYPNPNYSYSTMANSPPPHHSPLTLFPTLSPPSSPRYRAGLIRSLSPKSKHTPENACKTKKSSLLVEAGEATRFTSKDACKILRNDEIISLELEIGLINESEQDLDLELRLGFA
The following text describes a protein:
Function:
Mitochondrial electroneutral antiporter that exports citrate from the mitochondria into the cytosol in exchange for malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis-aconitate and to a lesser extent trans-aconitate, maleate and succinate. In the cytoplasm, citrate plays important roles in fatty acid and sterol synthesis, regulation of glycolysis, protein acetylation, and other physiopathological processes.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MFEFLSNQMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQCSANPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDDPNKPMNPMVTGVFGAIAGAASVFGNTPLDVIKTRMQGLEAHKYKSTWDCGYQIMKHEGLKAFYKGTVPRLGRVCLDVAIVFIIYDEVVKLLNKVWKTD
The following text describes a protein:
Function:
DNA binding protein that function as transcriptional activator. Is essential for normal postnatal growth and nursing. Is an essential factor for neuronal neuropeptide Y and agouti-related peptide function and locomotory behavior in the control of energy balance.
Subcellular Localization:
[Isoform 1]: Nucleus; [Isoform 2]: Cytoplasm.
Sequence:
MNLNFTSPLHPASSQRPTSFFIEDILLHKPKPLREVAPDHFASSLASRVPLLDYGYPLMPTPTLLTPHAHHPLHKGDHHHPYFLTTSGMPVPALFPHPQHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAADGPESPEGSPRAPEGAPADARLSLPAGAFVLTEPEDEVDIGDEGELSSGPHVL
The following text describes a protein:
Function:
Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MTNQESQSVKVVFVTRDETLQPEAPLPPVMVPTSLKRLGLSEIVNQLLDTETPVPLDFLIVKATAGDGGASILDEESASSSSVLLRPGASLESFLADNGLSSEVSLSIEYIRSVLPPSFLASFSNPDWVAAVDINARWTGDLKPVIASGSYDGVVRLWDHSGHVTGQLVGHNSAAKAVRWISNDQLVSGGSDRLLYLWNPDGKKYRRKEPGQVGKKELNYDSEEDSDEEMLDELPAASTVTPMAALHGHTAPINDLAVHAKTGKIISASADGSVGLWSTDYNDMPAIEPHTAAAGGLTSTSAQKRRKLANSGSGATGLGAARQRGPLAVMGGHSAAVSAVAFHHSDPTVAYSVSLDHTIKTWDLATAEAVQSNAGSPDPSVDTRSTSFSLLSLCTLPQGLIACGSSARHITLHDPRVTAQVATQAKLVGHTNFVSSLSRGPESNPFLLASGSHDGTVRIWDVRTTKSLHVIHRETLTENNAVFGVDWKQNLGIVSGGQDNKIQINNNPQSA
The following text describes a protein:
Function:
Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity (By similarity).
Miscellaneous:
MISCELLANEOUS: Present with 1900 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MMKRCFSILPQNVRFSSKFTSLNLPKLDLADFIDSNKRGINVLPSYRDETASTTQATNSKELRLLSKTLQGQSYRDQLELNPDVSKAINNNIMAVHIPNNLRRVATNYYKEIQEPNSLHRPCRTKMEVDAHIASIFLQNYGSIFQSLKELQKRVGPDNFKPQRILDVGYGPATGIVALNDILGPNYRPDLKDAVILGNAEMQERAKIILSRQLNEVVDTVEENVSTEKEQETDRRNKNFQEDEHIGEVMTKKINIMTNLRSSIPASKEYDLIILTHQLLHDGNQFPIQVDENIEHYLNILAPGGHIVIIERGNPMGFEIIARARQITLRPENFPDEFGKIPRPWSRGVTVRGKKDAELGNISSNYFLKVIAPCPHQRKCPLQVGNPNFYTHKEGKDLKFCNFQKSIKRPKFSIELKKGKLLATSWDGSQGNASRLKGTGRRNGRDYEILNYSYLIFERSHKDENTLKEIKKLRNENVNGKYDIGSLGDDTQNSWPRIINDPVKRKGHVMMDLCAPSGELEKWTVSRSFSKQIYHDARKSKKGDLWASAAKTQIKGLGDLNVKKFHKLEKERIKQLKKEERQKARKAMESYNELEDSLQFDDHQFSNFEVMKKLSTFHGNDFLQHVNRK
The following text describes a protein:
Function:
In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activity on various fatty acyl-CoAs (By similarity). Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation (By similarity). Abolishes BNIP3-mediated apoptosis and mitochondrial damage (By similarity).
Subcellular Localization:
Mitochondrion.
Sequence:
MALLRGVFIVAAKRTPFGAYGGLLKDFSATDLTEFAARAALSAGKVPPETIDSVIVGNVMQSSSDAAYLARHVGLRVGVPTETGALTLNRLCGSGFQSIVSGCQEICSKDAEVVLCGGTESMSQSPYCVRNVRFGTKFGLDLKLEDTLWAGLTDQHVKLPMGMTAENLAAKYNISREDCDRYALQSQQRWKAANEAGYFNEEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPSVFKKDGTVTAGNASGVSDGAGAVIIASEDAVKKHNFTPLARVVGYFVSGCDPTIMGIGPVPAINGALKKAGLSLKDMDLIDVNEAFAPQFLSVQKALDLDPSKTNVSGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIALIIQNTA
The following text describes a protein:
Function:
Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division.
Miscellaneous:
MISCELLANEOUS: The formation of the non-consecutive disulfides depends on the periplasmic disulfide isomerase DsbC. The disulfide bond between Cys-109 and Cys-124 is particularly important for the assembly of an active RcsF.
Subcellular Localization:
Cell outer membrane; Lipid-anchor; Periplasmic side.
Domain:
Contains an N-terminal proline-rich region (PRR), which probably plays an important role in the regulation of function of RcsF and activation of the Rcs signaling system.
Sequence:
MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAPRATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKANAVLLHSCEVTSGTPGCYRQAVCIGSALNITAK
The following text describes a protein:
Function:
Required for maturation of 30S ribosomal subunits.
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTGLPSQRQVIELLGADFACAGYEIEDVVIDARARPPRIAVIADGDAPLDLDTIAALSRRASALLDGLDGANKIRGRYLLEVSSPGVERPLTSEKHFRRARGRKVELVLSDGSRLTGRVGEMRAGTVALVIREDRGWAVREIPLAEIVKAVVQVEFSPPAPAELELAQSSEMGLARGTEAGA
The following text describes a protein:
Function:
Required for meiosis and spore formation. Seems to be involved in the coordinate induction of late meiotic events. PLD activity is induced under sporulation conditions and seems to be necessary to complete the meiotic cycle, but not for vegetative cell growth.
Miscellaneous:
MISCELLANEOUS: Present with 49 molecules/cell in log phase SD medium.
Sequence:
MSNVSTASGTHFAPPQADRSVTEEVDRVNSRPDELENQEVLRQLPENGNLTSSLQREKRRTPNGKEAERKHALPKSFVDRNLSDVSPNHSLDHIMHSNEHDPRRGSDEENMHRLYNNLHSSNNNVHSKRNSKREEERAPQRRSSSVAYTQQQFNGWKKEFGHAFKKISAIGRLKSSVNSPTPAGSGHRHNQHQHQQVNEEDLYTQRLASDLLDSLLAGCPASLFASTQFLRDEHGKRRAPLLLAKLDVRVSPLKNDNNILDITNSNHNHRGNNNNNTGENSDRRPSIPRSSSIISISSNVAEFMYSRNENSLFRIHLEYGIDEDRLKWSIIRSYKDIKSLHHKLKIVAFQQLTISKLYSDNNRYHSLQLPHFPHYKEMVKERNVMEKKAENKPSSAASAPHTSENNNNDNGSNITSLETLSSSEISEFNIDNVKMKHLQDLIDEPDDFSQPIHLRLERYLRLLNIALCLRPHANRLFEFYELSPLGNLLSRESGFQGKQGYLVIRSTAKAQGWRVSHFGKHAFKDMIDRHTTKWFLVRNSYLTYVSDLSSTTPLDVFLIDWKFKVRFSGNKNNILDNENEINWIIHDPNLEINDELEEFGIENDANNILDKNGKSKTHQKKSNISSKLLLLTLENSERKLKIICKSESSLKQWMSSIIKMSTSTPWSKPNRFGSFAPVRTNSFCKFLVDGRDYFWSLSEALLMAKDVIYIHDWWLSPELYLRRPVKGNQGFRIDRMLKSCAEKGIKIFIVIYRNVGNIVGTDSLWTKHSMLNLHPNIHIIRSPNQWLQNTYFWAHHEKFVVIDETFAFIGGTDLCYGRYDTFEHVLRDDAESLLDQNFPGKDYSNARIADFHDLDKPFESMYDRKVIPRMPWHDVQMMTLGEPARDLARHFVQRWNYLLRAKRPSRLTPLLTPPSDLTAEELKSLPMFEILREKSTCETQILRSAGNWSLGLKETECSIQNAYLKLIEQSEHFIYIENQFFITSTVWNGTCVLNKIGDALVDRIVKANQEKKPWKAFILIPLMPGFDSPVDTAEASSLRLIMQFQYQSISRGEHSTFSKLKKLNIDPAQYIQFFSLRKWSTFAPNERLITEQLYVHAKILIADDRRCIIGSANINERSQLGNRDSEVAILIRDTDLIKTKMNGDDYYAGKFPWELRQRLMREHLGCDVDLVEFVEKKFERFEKFAAKNYEKLHTLSKEGDSGNNWSDREMIDSAMIELGYREIFGCKFSPQWKSGHGNSVDDGSTQCGINEKEVGREDENVYEKFFNSVDYGKSSRKRTPLPKHNFASLGLTFNHRAGIENVGIRDHKVLSTDPRLRKNDEHKKEVDGYGPDCWKKESNKKFKADATEQLKEWALNSLASKVLDDKEMIKSEIPEGFSNYLPNEKDLEMYLTDKTVTNRNKWSMLKRICYLQYLSHKLDERKTQRLKKIKDMRRHLSSSTESTRNGSNSLPLNEKSNEGESTNVDQDIEGDEYHRLHEDILKNQELDDGSLDDLLSQIIPKITNFNSGEIDDAKKEELLKLNFIDPYSFEDPLISSFSEGLWFTIALRNTLLYKLVFHCQPDNAVQNWKEYGEFTELEQEFQINQEKLIDLEAENINSTTTNVVDKDREKEKMRKAAELRMKLSGSLLYGFNQKVFDKHTAQRILERIHGHLVIFPTEWLAKEVESRNWIFNSDRLSPMEIYN
The following text describes a protein:
Function:
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Zona pellucida.
Sequence:
MFVIAALIVNSMYLINAQDLQFPREMPQYHDGGGLPFSPVLKDKQEKFNLRRESFSPESPLSSTGSQRCVVPQFERIECGEPDISPTECEDISCCYGDQGCYYRKAVTLQCTRDGQFVLVVARDATMPGISLESIHMLEDDPAHCAPVGSTGSFAIYQFAVSTCGTTMKEERGFVIYENKMSSVYEVGLEPHGSIMRDVYELKFQCRFSATAVEAVVIEMKTPPSSPPPPAPHVSQQGSLQMELRLAHGLCTSKGCPDEDMYTSYYSDTDYPVTKTLREPVYAEVRMLNTTDPSITLHLEHCWTTSNPEALTQPKWDLLENGCPHNDHHERTTMLSVGSSGLQFPSHYRRFIVNVFPAVDQSSLPLRIFIHCITSVCHPSETESCEPICDHTTKRVITEELKHSKEKFVVSSGELTLVSSLPVSDHLVVHEQVVGQMLDSGLWAAGALTVFALCGFTIAVLTHRLRPAPQPVPV
The following text describes a protein:
Function:
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKPSATSERTNGLASPTATFEEESVTPPSAEPPHVRLVIALEPLLTVLSIVLDLVKVILLGVPLIVREIYTMFVPRPQKDVRGQVALITGGGNGLGRAMAQLFAARGCHLVLVDIDLQAAERTAEELRQQYGVAARAYRVDVSQYEQCRALGEQIERDGAGPVDILINNAGLIMFAFVNDSDVERANSVIDVNMKSHVWMTKVFLDGMIKRKRGHIIGISSMSGMYAFPWGVVYSATKFAVSGFMASLTEQLRIQGLSKSVRTTCVNPYYVTTRKDVIEFLQKPRFAPLTVDEAAREIVKGILRQDIVVTIPRLFGVFTRFMLFFPVPVQQLVRDYLIREYELNNNLHM
The following text describes a protein:
Function:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MHEHLVLTDHSGGGGAAGSAAGLGGGGLEFPCGAIKEEKGIQRLEAMLYALDLINDDPHILPNITIGAVILDTCSSDTHALDQSMEFVRSYMNKDASEYQCESGDAPRYVPHKPITGVIGASFSTESIMVANILRLFKIPQISYASTSAELSDKSRFEYFSRVVPPDNFQAQALVEMVRQLGWKYVSTVAVEGDYGEKGIASFVTLAEAAGICIAVSEKILRRAEDADYDRIIERLSQKSSARGVVMFADEDETRRMLAATMRLNKTGQFLWVGSDSWGAKLHPVRDQEFAAEGAITILPKRSSLAGFDAYFKALRPKTAKVANASGNGENQYYRNAVKGSRIYNCRNPWFRQFWEQHFKCRFNSSASASGTGQSSSTLPECKGGDKLTYYEQEGLVPFVVDAVYAMAHAVHRMIADVCGHDARELCDELKPAPSGRNLLKYIRNVNFIGPQGQPVRFNKDGDAYGSYSFYQYQRHGSKYDYVRIGDWSASLVLNMSMLAWPNSTRGTIPRSICSDSCPNGYIRNFQDQCCWSCVSCREDSYSFNDTCVACAPGYAPNRDFNGCDKIPAEHLTWDSPWAIVPLVFTALGVTATLFTLTVFLRYNSTPMIMASGRELCYLLLTGILLCYLMAIPILAKPNVFTCSLLRVGLGFALCLCYSSILTKTNRISRIFNRGSKAGIKRPSYTSPKSQIVICCGLASIQLGGSLVWLMFERPSTKEVHPQPLTAILTCGVSNLSLVLSLLYNMLLIILCTFYAFKTRKIPENFNEAKYIGFTMYSTCIVWLAFVAIYFGTYNDYKIQTATLCVCVNISASVALGCLFVPKVYIVLFQPYKNVRTPGSGVINNLFIVE
The following text describes a protein:
Function:
Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2. Thereby acts as an antagonist of FGF-induced retinal lens fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis. Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells. Inhibits CBL/C-CBL-mediated EGFR ubiquitination (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell projection, ruffle membrane. Note=Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).
Domain:
The Cys-rich domain is responsible for the localization of the protein to the membrane ruffles.
Sequence:
MEARAQSGNGSQPLLQTAHDSGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQPSQVHSSRAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGPSFSHGPAAADGIIRVQPKSELKPGDVKPLSKDDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
The following text describes a protein:
Function:
Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
Subcellular Localization:
Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Sequence:
MPPTPPDTRTHTHAHTHTHTHTPAGPRPLPAGEELREESAARRRDPGAAPAPGEPAGKAFPGAAGGGGWGARAEGGGGGGARAEGGGGGAARGRGARGGARGEGARGEGRAGGGARGGGRRGEGAGGGGGGGGARGGRGARGGAARGEGRAGRGGAGRGARGGARGEGRRDPAPGAGPVRGTPGGRPRREVSSLRAPRGRPDAPDPAMRPLLLLAPLGWLLLAEAKGDARPEDNLLVLTVATTETEGFRRFKRSGQFFNYKIQALGLGEDWTGEKGTSAGGGLKVRLLKKALEKHADKEDLVILFTDSYDVVFASGPRELLKKFRQARGQVVFSAEELIYPDRRLEAKYPAVSDGKRFLGSGGFIGYAPSLSKLVAEWEGQDSDSDQLFYTQIFLDPEKRERINITLDHRCRIFQNLDGALDEVVLKFEMGHVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCSVCDEGLRSLRGIGEEALPTVLVGVFIEQPTPFLSLFFLRLLRLHYPRKQMRLFIHNHEQHHKAQVEQFLAEHGSEYQSVKLVGPEVRVANADARNMGADLCRQDRGCTYYFSVDADVALTEPKTLRLLIEQNKNVIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELQHTDLFHHSRLDPDMAFCANIRQQDVFMFLTNRHTFGHLLSLDSYQTSHLHNDLWEVFSNPEDWKEKYIHENYTKALAGKLVEMPCPDVYWFPIFTETACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQISFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTRGTRYIAVSFVDP
The following text describes a protein:
Function:
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Sequence:
MLGGNPLCRQRLFRGISATALGRPTAAATREPGNLPRQNPCPRAGCPVGRLQPGTFARSPRKSSARSQPPNITGLPMSASYDFDQYGHLIELPSVRQPSAQAKPTTPELCLVQPPALPAPLPRPPARSPTPSDLSLDRSRDDLLTSFGRLTLTDRYLLAGEGLQDMFARVSCAFADNVAHAQRLYDAMSRLWFMPATPVLSNGGTTRGLPISCFLNSVSDSLEGIVGTWNENVWLASNGGGIGTYWGNVRSIGEKARGGVTSGIIPFIHVTDGLTLAISQGSLRRGSAAVYLDIHHPEIEEFLEIRKASGDFNRKSLNLHHGINVTDEFMCAVGAGTAFALRSPKTNEVVREIDARQLWQRILENRLQTGEPYLLFIDTVNRALPKHQRELGLEVSTSNLCSEITLSTGIDHRGEERTAVCCLSSLNLETWDQWNEEPGFIEDVMRFLDNVLTHFITVAPDGMKRARYAALRERSVGLGVMGFHSFLQAKGIPMEGTLAKSFNLNMFRKLRREADAASVALARERGPCPDALERGVMARFSHKIAIAPTASISIICGGTSACTEPIPANIYTHKTLSGAISVRNPHLAKVLAAKGADTSATWESIIAHDGSVAHLDVLSEHEKAIFRTAFEIDQRWIVELAADRAALICQSQSINLYLPADVDKWDLHMLHWTAWKRGVKSLYYCRSKSISRAAFAGKIAGDATPTQQPARQRTDYEECLACQ
The following text describes a protein:
Function:
Polymerizes to form the tail tube of the phage. Tail tube protein polymerization takes place around the tape measure protein (TMP-pb2) and is probably directed by chaperone proteins (Probable). The tail tube is involved in viral genome delivery during ejection (Probable).
Subcellular Localization:
Virion. Note=Main component of the tail tube, which is made of 40 stacked TTP-pb6 trimers.
Domain:
The C-terminus possesses an Ig-like fold of the Big-2 family.
Sequence:
MSLQLLRNTRIFVSTVKTGHNKTNTQEILVQDDISWGQDSNSTDITVNEAGPRPTRGSKRFNDSLNAAEWSFSTYILPYKDKNTSKQIVPDYMLWHALSSGRAINLEGTTGAHNNATNFMVNFKDNSYHELAMLHIYILTDKTWSYIDSCQINQAEVNVDIEDIGRVTWSGNGNQLIPLDEQPFDPDQIGIDDETYMTIQGSYIKNKLTILKIKDMDTNKSYDIPITGGTFTINNNITYLTPNVMSRVTIPIGSFTGAFELTGSLTAYLNDKSLGSMELYKDLIKTLKVVNRFEIALVLGGEYDDERPAAILVAKQAHVNIPTIETDDVLGTSVEFKAIPSDLDAGDEGYLGFSSKYTRTTINNLIVNGDGATDAVTAITVKSAGNVTTLNRSATLQMSVEVTPSSARNKEVTWAITAGDAATINATGLLRADASKTGAVTVEATAKDGSGVKGTKVITVTAGG
The following text describes a protein:
Function:
Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3.
Subcellular Localization:
Nucleus.
Sequence:
MTQTKVIQVTNVAPAATKEQMQTLFSFLGKIDEIKLYPEDISVPVTSKVCYVKYDDPTNCGVAQHLTNTVFIDRALIVVPCQDGIIPDEAKALQLAAPANAVAGMIPGGAAPAASALLPTPAPIANPLLAAAGVAGGEVLGATLADQDILGAFFPESVSKDVLGSGMGDQLPPLPGNVDPSKIDEIRRTVYVGNLDSATVTAEQLLNFFQQVGEVKYVRMAGDETQPTRFAFVEFADQTSVAKALQYNGIMFGNRPLKINHSNNAIVKPQTQTPEAQRREIEEAMKRVRDAEALITAAIEPGTMTAATLQIPAIEKPTLRSSEISEKKDDKRRRSRSRSRSYSRRRRSRSRSPRRSRSRRSRSRSRHRRSRSRSPKRRSRSPRRRRSRSRERRSRSRSRRSPSKSPARRHSATAKGRRRSRTRTPPRSYRTTSRLSRSKSSCGCPQTRDAPSERMARSPRRRSRTPKRSPSKSPARRTSSSKHKKEKKKDKDKDRDRSGSRERDTTKSKKKKKDKDKDKDREREKDKEKHRGKSKEQEEEKKEAKVTRDYDEEEQGYDSEKEKVAKAPAPEAPVEQPAEAPPSSEEFGDSGSQGQADMDVDSD
The following text describes a protein:
Function:
An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
Subcellular Localization:
Cytoplasm.
Sequence:
MDKEKDKAKDRVKDKEKDKIKIIPLGGLNEIGKNLTAIEYKNDIVVIDCGLKFPDDDMLGIDVVIPDITYLKKNINKVKGIFLTHGHEDHIGALPYVLRAVNVPVYGTKLTLGIVETKLKEHGLLSSVELKCIKPREIIRLQNVSVEFIRTSHSIADTVAIAIHTPLGVVLHTGDFKIDYTPIDGHVTDLARFAEIGKRGVIAMMADSTNVERPGYTMSESTVGEAFLNIFSGVKGRIIVATFASHIHRIQQIIRAAEKFKRKVAVSGRSMENIMEVAMKLGYIKAEKNIFISIDAINKYPDDQVVIITTGSQGEPMSALSRMAASEHKKVNIKPGDKVIISATPIPGNEKLVSRVINQLFKKGADVIYETLADIHVSGHACQEELKLMHTLVRPKYFIPVHGEYRHLKQHGELACQLGLPENHVMVSDIGDVIEVSRECIRKNGSVVSGQVFVDGLGVGDVGNIVLRDRKHLSQDGILTVVVTIEKVSGSVIAGPDIISRGFVYVRESEDLMEEAKDLVKKALEECERNHITEWAAIKTNIKDVLRGFLYEKTKRKPMILPIIMEI
The following text describes a protein:
Function:
Tyrosine-protein kinase which plays a role in RNA-mediated gene silencing by mediating import of double-stranded RNA (dsRNA) into cells. Not required for import of ingested dsRNA into intestinal cells but involved in subsequent export from intestinal cells to internal tissues.
Subcellular Localization:
Cytoplasm. Note=Displays diffuse localization in cytoplasm and cytoplasmic foci, and also in a punctate pattern.
Domain:
The kinase domain is required for import of dsRNA into cells.
Sequence:
MASTSGALVDDNVLEVLRKAQLDAFISQFVFLFNVRRFDHFSHVRDKDMLEIGMQQVQIRQLREQILKMSREMWNRSDPKQVYIQADQSMPAQNSIDEKALIPNEQIKLYELIGEGSFAVVKRGTWTQSNGTHVNVAVKILRDISPNIMDDLRVEASHLLKLQHPSLIRLYGIVRQPAMMVFELCEGGSLLDRLRDDKKAILLVSRLHDYCMQIAKALQFLESKHCVHRDVAARNILLARDERTVKICDFGLMRALKENEQMYTMAPQKKVPFAWCPPEALRHRKFSHASDVWSYGVTIWEVFTFGEEPWVGCRAIDVLKNIDAGERLEKPKYCSERIYQIMKNCWKFNPAERCKFGAIREDLVAAMFLDAVARETYNSIQPGALQLTKGDEVVVVENTGQDWFGQNKKNQKFGTFPRSVVFAQTNNAVAAATAVTPQKVPTAPTIRIPPSHPPPAPLKPLNNNTKTSLNDRTSKISMPVAGSFIHTGHGDPLGGQSWGNPATIADMYLKNPVNGAPLSSMSSGAEIIASKELLTNGGRSTHQPAAPSPAVMSKIRGLSLDLPEYDDFDRAFDDGFSPSKIELPREFCGNDSVISGGSNSIGLANTYVMEPPKQAFDIRGNRVLPPTNKAPVLIPTNPAPSVISSTASAGITLSTNSSQMFTSQDRHSNMPANLFPELQHRLNQGSSTGNGVRPRPASSIGIQNNDLSMLNPQVNRPFSVVNVPIVQQPANIPCLVPTPAPPAPAHFSQPVSSQRVAQQQQNTLQKALNDELKGNLNKRPTGTTAPPSNGFNAPRADVAPVQQRPISSASIPALQPQPIQHIQKPIQPQQVRIPPSTAPVQKPVQVSAPTHSNVAPTTSSQASADARNPLPPKTSPPVSNTPITVAPVHAAPTTSAPSTSVVTRRPTSTTAQMSDEERRSRIAMDISSALPAPSALLYGSNSTSSLPSAAVSTASSVPSTARDNPVETRPSQPHVTMPPKKSSEPILSSEVLQPTRLPSATTSQAKPVTQPIRHPSPPVATVIPTAVVDKKPVSQNQGSNVPLFNITNSSNGYPQLNGYPNYGNGFQAYGYGMNYHQGYPGYQGYNSYGNGMGQLALTHNAVTSLPPLVPSENRFSGTAQPLGESDIMEFLGTQQRQAGSSSRAVPPASASTSAASGITDLSMADKMEVLYREADFTHKGNCDTMVSQCNGNTEQALKLLKQQHLVDMELAMSTETARQALEARQYDLPAAANMLLG
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MGTKALLFFALFSLLAIASVADTESTESDSGLILNFYRDSCPQAEDIIKEQVMLLYKRHKNTAFSWLRNIFHDCGVESCDASLLLDSTRRTLSEKETDRSFGLRNFRYLETIKEALERECPGVVSCADILVLSGRDGIVALGGPYIPLKTGRRDGRKSRADILEQYLPDHNESMTVVLERFKNIGIDTPGVVALLGSHSVGRTHCVKLVHRLYPEVDPVLDPGHVEHMLHKCPDAIPDPKAVQYVRNDRGTPMKLDNNYYRNILDNKGLLIVDHQLATDKRTKPYVKKMAKNQDYFFKHFGRAITVLTENNPLTGNEGEIRKQCNVANKRH
The following text describes a protein:
Function:
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
Subcellular Localization:
Cytoplasm.
Sequence:
MEEKDLIENEEKEKTEEYVPNEWEIKYVRLQAEFENFRQRLRREKEEWQEIANARLLKEIVEIMDNFQLALESIKHTRKKDAIIEGVQMIYKQFENLLEKEGVVKMETIGKNFDPNLHEAVGIEEVSDGEDNVILKEISPGYLFKNRLLRPARVIVSKKIQKKEVDEHGEDSRN
The following text describes a protein:
Function:
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytosol. Mitochondrion. Nucleus.
Sequence:
MAAKKYFDIMKMFLQMEKGSKNYSSIVNTCRVIKADEGKISVEFEVDDRMTNHFGTLHGGCSATMVDVITTGALVATPRGMPGVSVDLHMTYLAAAKLGDTVQLDAEVIRQGKSMAFTKASLYRKPEMTLIATGLHTKAFPAHATIRKDVLEASSKVKMATKKYFDIITMFLQIRKGTKNYSSIVNTVDDRMTNHFGTLHGGCSATMVDVITTGALVTTPKGMIDRPSEMAVRVAAKLAAGLKTIGPVNPLHYRAMLRFFEMDREDATFTGLVWDARITNVEELKMSAEFMVTENKVRFIIVQIDLWSLFPIQHFGTLHGGCSATMVDCLTCAALIVATGRPAVSVNLNMSYMNPAPLGTLVRIDAQVVKIGNSLAYTMADLIGVKKDGVEIEIASAKHTLAFSKRVYVRERTERQFNIS
The following text describes a protein:
Function:
Bitter taste receptor that detects natural and synthetic bitter compounds.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MALSFSAILHIIMMSAEFFTGITVNGFLIIVNCNELIKHRKLMPIQILLMCIGMSRFGLQMVLMVQSFFSVFFPLLYVKIIYGAAMMFLWMFFSSISLWFATCLSVFYCLKISGFTQSCFLWLKFRIPKLIPWLLLGSVLASVSIASVCIEVDYAKNVEEDALRNTTLKKSKTKIKKISEVLLVNLALIFPLAIFVMCTSMLLISLYKHTHRMQHGSHGFRNANTEAHINALKTVITFFCFFISYFAAFMTNMTFSLPYRSHQFFMLKDIMAAYPSGHSVIIILSNSKFQQSFRRILCLKKKL