lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host coxsackievirus and adenovirus receptor CXADR located at the cell tight junctions to provide virion initial attachment to target cell. The fiber protein binds to CXADR with a higher affinity than CXADR binds to itself, thereby blocking the cell-cell adhesion function of CXADR dimers and leading to local disruption of the tight junction. Fiber protein present on neo-synthesized particles may thus disrupt the junctional integrity in order to facilitate further neighboring cells infection. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Fiber shedding is dependent on viral CXADR drifting motion and subsequent binding to immobile integrins. Heparan sulfate might also play a role in virus binding (By similarity).
Miscellaneous:
MISCELLANEOUS: All late proteins expressed from the major late promoter are produced by alternative splicing and alternative polyadenylation of the same gene giving rise to non-overlapping ORFs. A leader sequence is present in the N-terminus of all these mRNAs and is recognized by the viral shutoff protein to provide expression although conventional translation via ribosome scanning from the cap has been shut off in the host cell (By similarity).
Subcellular Localization:
Virion. Host nucleus. Note=Anchored to the pentons, protrudes from the virion surface. Present in 36 copies per virion (By similarity).
Domain:
The tail region anchors the fiber to penton base capsomers, whereas the shaft, built from several repeated motifs, allows the knob to protrude from the virion.
Sequence:
MKRARPSEDTFNPVYPYDTETGPPTVPFLTPPFVSPNGFQESPPGVLSLRLSEPLVTSNGMLALKMGNGLSLDEAGNLTSQNVTTVSPPLKKTKSNINLEISAPLTVTSEALTVAAAAPLMVAGNTLTMQSQAPLTVHDSKLSIATQGPLTVSEGKLALQTSGPLTTTDSSTLTITASPPLTTATGSLGIDLKEPIYTQNGKLGLKYGAPLHVTDDLNTLTVATGPGVTINNTSLQTKVTGALGFDSQGNMQLNVAGGLRIDSQNRRLILDVSYPFDAQNQLNLRLGQGPLFINSAHNLDINYNKGLYLFTASNNSKKLEVNLSTAKGLMFDATAIAINAGDGLEFGSPNAPNTNPLKTKIGHGLEFDSNKAMVPKLGTGLSFDSTGAITVGNKNNDKLTLWTTPAPSPNCRLNAEKDAKLTLVLTKCGSQILATVSVLAVKGSLAPISGTVQSAHLIIRFDENGVLLNNSFLDPEYWNFRNGDLTEGTAYTNAVGFMPNLSAYPKSHGKTAKSNIVSQVYLNGDKTKPVTLTITLNGTQETGDTTPSAYSMSFSWDWSGHNYINEIFATSSYTFSYIAQE
The following text describes a protein:
Function:
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
Subcellular Localization:
Cytoplasm.
Sequence:
MKKIGFVGAGSMAEAMINGILQSGITKPEHIYITNRSNDERLIELKETYSVRPCRDKNEFFTHTDIIILAFKPKDAAESIDSIRPYIKDQLVISVLAGLTIETIQHYFGRKLAVIRVMPNTSAAIRKSATGFSVSTEASKNDIIAAKALLETIGDATLVEERHLDAVTAIAGSGPAYVYRYIEAMEKAAQKVGLDKETAKALILQTMAGATDMLLQSGKQPEKLRKEITSPGGTTEAGLRALQDSRFEEAIIHCIEETAKRSAEIKEQFAGAALERHS
The following text describes a protein:
Function:
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
Sequence:
MSKSKVQGQTPAITNQNESSNGSQPEIHLNNPNIFFDRELSWIDFNRRVLEEANDPENPLLERLKFLSITETNLDEFYMVRVAGLRNLVKEGNDERSLNGDSASEILSDLSDKVRVFVREEYETFARTLEELKVAGIHLILNPEELTIEEIKQIQNYYQEDVSPILTPLAIDTAHPFPHILNKSLNLAMVLSTDDEKTGGKKDLFAVVQVPSVLPRFLQLKGKGEERRFFPLEEIIKLHVDDLFYGMTVREIYPFRIIRDADISIDEEKSVKDLLITMKDELRNRIWGDAVRMDIHQGTSPFIKNTLRELLELQDNEVFDVASILNINDAMFFYGLDHTSKLKYPFFQQKTTLKFETPEKIFEAIKKKDRLLHHPYQSFSAIEDLLRISSEDPKVLGIKMTLYRTSGDSPIIQYLGEAAENGKQVTVLVELKARFDEERNIKWAQKLEARGVHVVYGVVGLKIHCKMLMIVRKEDDHLVRYVHLGTGNYNSTTSKYYTDLSFFTVNKQITEDVATIFNTITSYAKMPTLNLLSASPHNLKSTFISLIDKEKENALSGKPARIIFKMNSLVDPHIILSLYKASQAGVKVDLIIRGICCLKPGLKGISENITVLSIVGRFLEHTRIYYFHSGGFESVFLASADCMPRNFERRIEVLFPIIESKNKERIKKILDVQLRDNVKARFLRPDGHYVKKILEKDEKPVDSQIERMTFAE
The following text describes a protein:
Function:
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Subcellular Localization:
Cytoplasm.
Sequence:
MSQAPQAGQQQAQKSNTFNKSEKTKDIRLTNIQAAKAVSDAVRTSLGPRGMDKMIQDAKGQVLITNDGATILKQMDLVHPTAKMLVEISNAQDVEAGDGTTSVVVFAGALLKSCEVLLEKGIHPTTISEGFQFALEYALTALDELKKPVDLENKQQLIECVQTALSSKVVSSNSAQLAPLAVDAVLRIVDPQKPNNVDLKDIKIVKKLGGTIDDTELVEGIVFSNQKASQAAGGPQQIKDAKVALLQFCLSAPKTDVENSIAIKDYTEMDKILKEERKYIIDLVKKIVASGANVLLIQKSILRDAVNDLSLHFLAKKGIMVVKDIERDDVEFISKTLCLVPVAHIDQLTPEKLGTAGLVETVHLNDESKVLRITKVPAQSKALTILVRGSNQLVLDEADRSIHDALCVVRSLVKSKGLIPGGGAPEIHLSLRLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYQIKNAHQRLSQFSRYLRRCFSQKIVIISYQISTLDHLIPDKSIKNKKKELHKNYKKFNNLSIALNSNEQINLTNDELQLFQSIKNSPQKQQNNNKFPDQKKTRKQKLIEFLKGQHQNIQFTTLLQRKSLKDQALLPSFIITKYQELQF
The following text describes a protein:
Function:
Forms chloride channels.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MTMSYNCDVATDSYFNFFKILFRWKGSVWKSIWKELALWIVTYYTIKAVYMTLDDDRKIIFDKNFLPKIANFDLSVLTFMLTFFVTTIVARWNKIFDNMGFIESAAYAIAAFMDDKNDEPILKPAQEKKEIIKLEDRTDSVEKESDKNTKNKKKSSGEQNKTVKSGAENMKILKPDAVKYVEKQKELEKLNAAKKEEERMELEKLDAERKNKLRMARRTIIRYLVASQVLVLRTISMRTLRRFPNYTSIVAAGFLHQDEADIIENMDFEYDRTWVPIRWATEILREQFMAVSATNKDHPFAAPSLYSAAWQEIKNFQASISVVKNADWVPIPLAYPQVIFFAVRLYFIFCTFTRQHMLTDPEIDRTIDSSNYITYYIPLGNIFQFICLMGWVKVSEALLNPLGEDDDDFEVNFLIDRNIYTGMAIVDTEYAECPALKKKNLGKEKIDAFEGEHARPFYPHGMDGSIGDALVGSAQNMKFDDPPEMKQFSVNITPSKPRPTPLKPKNKEGAQRKISNASTFSTSTFNESGYSTNKAGALGPIPISFDTPNVGVNKK
The following text describes a protein:
Function:
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation.
Subcellular Localization:
Nucleus.
Sequence:
MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGIKGKADAGKDGNNPAENGDAKTVQAQKAEGAGDAK
The following text describes a protein:
Function:
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular Localization:
Cytoplasm, cytosol. Rough endoplasmic reticulum.
Sequence:
RGRPLGIAHCSPELLGSSDPAGSASRVAGTTGVRHRARQRHRRSAATTALLTADVTPRREGERHALRTRCLPCSRACALCRVRAAPRCRAGGRAGLISACAGRHLPLTAGHAAGSMGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD
The following text describes a protein:
Function:
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein. Note=Cell membrane associated, also colocalizes with FtsZ to the nascent septal site. Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Sequence:
MEFVIGLLIVLLALFAAGYFFRKKIYAEIDRLESWKIEILNRSIVEEMSKIKHLKMTGQTEEFFEKWREEWDEIVTAHMPKVEELLYDAEENADKYRFKKANQVLVHIDDLLTAAESSIEKILREISDLVTSEEKSREEIEQVRERYSKSRKNLLAYSHLYGELYDSLEKDLDEIWSGIKQFEEETEGGNYITARKVLLEQDRNLERLQSYIDDVPKLLADCKQTVPGQIAKLKDGYGEMKEKGYKLEHIQLDKELENLSNQLKRAEHVLMTELDIDEASAILQLIDENIQSVYQQLEGEVEAGQSVLSKMPELIIAYDKLKEEKEHTKAETELVKESYRLTAGELGKQQAFEKRLDEIGKLLSSVKDKLDAEHVAYSLLVEEVASIEKQIEEVKKEHAEYRENLQALRKEELQARETLSNLKKTISETARLLKTSNIPGIPSHIQEMLENAHHHIQETVNQLNELPLNMEEAGAHLKQAEDIVNRASRESEELVEQVILIEKIIQFGNRFRSQNHILSEQLKEAERRFYAFDYDDSYEIAAAAVEKAAPGAVEKIKADISA
The following text describes a protein:
Function:
Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MSRQTKHFDRRFQLALLHPKYWVTWLAIGLLVIFGIMPAWLRDPIAKVLAKLVVPIAKKPIGIARANLSACFPEKSAAEIETLINNNVENFVLVLLSQGELLIRSKAHLRRRVNLMGFEHVKAAQAAGQPVIFIMPHVWPIDYAGLRLNLELPMVTMAKAHKNGLFNWFNNRVRSSCGGHVYMREAGIRALLAELKRNNSFFYLPDEDLGPDQSVFTPFLGTVKATLPVVGRLAQAGNAQVLPVKIGYNQVTRQFDLTVMSAIATEDMVGKENEALALNKAVEQVILAYPEQYMWFLRLLKTRPEGQASIYQ
The following text describes a protein:
Function:
Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3 (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein. Note=Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton.
Sequence:
MGPPWSQESSPEERLPTEWSRQLTRARWVLLAVLLCGLLLGSSMLWFYIFRNCGPCPCETPVCMELLDHYLASGNRSVAPCTDFFSFACEKANGTSDSFQALTEENKSRLWRLLEAPGSWHLGSGEEKAFQFYNSCMDTDAIEASGSGPLIQIIEELGGWNITGNWTSLDFNQNLRLLMSQYGHFPFFRAYLRPHPAPPHTPIIQIDQPEFDILLQQEQEQKVYAQILREYVTYLNRLGTLLGSNPQEAQQHASWSIVFTSRLFQFLRPQQQQQAQDKLFHVVTIDELQEMAPAIDWLSCLQAIFTPMSLNSSQTLVVHDLDYLRNMSQLVEEGLLNHRESIQSYMILGLVDTLSPALDTKFQEARRELIQELRKLKERPPLPAYPRWMKCVEQTGAFFEPTLAALFVREAFGPSIQSAAMELFAEIKDAVIIRLKKLSWISEETQKEALNKLAQLQVEMGAPKRAVKPDIATQEYNDIQLGPSFLQSFLSCVRSLRARNVQSFLQPFPYHRWQKSPWEVNAYYSISDHMVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIFYQLLLPGGCPACDTHVLQEALLCLERHYAAFPLPSISSFNGSHTLLENAADIGGVAIAFQAYSKRIVEHTGELTLPNLDLSPYQLFFRSYAQVMCRGLSSQDPQDPHSPPSLRVHGPLSNTPDFAKHFHCPRGTLLNPSARCKLW
The following text describes a protein:
Function:
Required for the proper distribution of nucleoids in chloroplasts. The nucleoid partitioning by YLMG1-1 may be related to chloroplast division processes.
Miscellaneous:
MISCELLANEOUS: Plant over-expressing YLMG1-1 have impaired chloroplast division leading to reduced number and enlarged chloroplasts in mesophyll cells. Plants silencing YLMG1-1 show a pale green phenotype in young emerging leaves and the basal part of expanding leaves.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Localizes in punctate structures on the thylakoid membranes which are adjacent to a subset of nucleoids.
Sequence:
MAAITALTLRSPVYLPSSATSPRFHGFTNQPPPARLFFPLNPFPSLSIQNPKSIRISASASPITTPILQTEKSTARSSTLTGSTRSLATLAALAIAVTRVLAQKLSLAIQTSSPVIADGLRFSLSTAGPVFFASLRDRPPGYLNTPLTVVAVGIKKWLDIYSGVLMVRVLLSWFPNIPWERQPLSAIRDLCDPYLNLFRNIIPPIFDTLDVSPLLAFAVLGTLGSIVHGSTG
The following text describes a protein:
Function:
Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Endoplasmic reticulum lumen. Note=Constitutively activated mutant forms with internal tandem duplications are less efficiently transported to the cell surface and a significant proportion is retained in an immature form in the endoplasmic reticulum lumen. The activated kinase is rapidly targeted for degradation (By similarity).
Domain:
The juxtamembrane autoregulatory region is important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand. Upon tyrosine phosphorylation, it mediates interaction with the SH2 domains of numerous signaling partners. In-frame internal tandem duplications (ITDs) result in constitutive activation of the kinase. The activity of the mutant kinase can be stimulated further by FLT3LG binding (By similarity).
Sequence:
MRALAQRSDRRLLLLVVLSVMILETVTNQDLPVIKCVLISHENNGSSAGKPSSYRMVRGSPEDLQCTPRRQSEGTVYEAATVEVAESGSITLQVQLATPGDLSCLWVFKHSSLGCQPHFDLQNRGIVSMAILNVTETQAGEYLLHIQSEAANYTVLFTVNVRDTQLYVLRRPYFRKMENQDALLCISEGVPEPTVEWVLCSSHRESCKEEGPAVVRKEEKVLHELFGTDIRCCARNALGRESTKLFTIDLNQAPQSTLPQLFLKVGEPLWIRCKAIHVNHGFGLTWELEDKALEEGSYFEMSTYSTNRTMIRILLAFVSSVGRNDTGYYTCSSSKHPSQSALVTILEKGFINATSSQEEYEIDPYEKFCFSVRFKAYPRIRCTWIFSQASFPCEQRGLEDGYSISKFCDHKNKPGEYIFYAENDDAQFTKMFTLNIRKKPQVLANASASQASCSSDGYPLPSWTWKKCSDKSPNCTEEIPEGVWNKKANRKVFGQWVSSSTLNMSEAGKGLLVKCCAYNSMGTSCETIFLNSPGPFPFIQDNISFYATIGLCLPFIVVLIVLICHKYKKQFRYESQLQMIQVTGPLDNEYFYVDFRDYEYDLKWEFPRENLEFGKVLGSGAFGRVMNATAYGISKTGVSIQVAVKMLKEKADSCEKEALMSELKMMTHLGHHDNIVNLLGACTLSGPVYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQAHSNSSMPGSREVQLHPPLDQLSGFNGNSIHSEDEIEYENQKRLAEEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILSDSSYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQSGFKMEQPFYATEGIYFVMQSCWAFDSRKRPSFPNLTSFLGCQLAEAEEAMYQNMGGNVPEHPSIYQNRRPLSREAGSEPPSPQAQVKIHRERS
The following text describes a protein:
Function:
Acts as a high-affinity cell-surface receptor for retinol-binding protein RBP4 and mediates RBP4-dependent retinol uptake in the liver.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLAASTRTRQINITCDNPVDREVFLHYSLIPSLCIILVLSFLQRREHRRQRDDTSYLLGNHFGIIVPLDFVGTFSNRWSYGAAFGATANKVMFLFSEGYQPLTVPQWAQAFVLFIGGMEVGLSYFPFFACLSSEFQLVSSILGFSYSLTWFVVTVLQISQCPHGQFLGRFETLVFYWPSLLCLGFLLGRFLHMFLKALPVHLGLEPQTEEKSMLEAHQAKHVKQLLSKPRPQEGEKSWFQTRVYEWDPCFQFPSRMVGTLLLAFICLYLFIVIEFCVFLHVRDKLDMFEDKLESYLTHMNETGTLTPIILQVKELISVTKGVWVVTILPAALTCVTYLFHILACYRKHMKRLWAGDKHFLPQKFHSPSSAASVVAIARYSGWQIAYILWGYLIIHVVQSLCGVMLMYGLVLPIIHHRGLEMLQGFGLGVLTLSIVVGLIILQVWIAGTFFLQPKLGTSDKQKPLALNNRRAFHNFNYFLFFYNVLLGLGACLSRLLISCLLGTWLIARIDRTIMQSGYEGADMGFGAWIGMLFVDHYHTNPVLVSFCHILITSHKDRKLQKTVKYWCLNQSAGPRFSARARTRWFLLQTLINNPRLVMLRKSKSGHSSGEFTQILLTCSDC
The following text describes a protein:
Function:
Methylates large ribosomal subunit protein uL3 on a specific glutamine residue.
Sequence:
MDKIFVDEAVTELRTIGDMLRWAVSRFNDANVYYGHGTDNAWDEAIALVFHALHLPEEIGQQVILSNLTSSEKHKIVELIIRRVRERLPVPYLTNKARFAGLEFYVDERVLVPRSPIAEMIANRFGPWLYGKPVNRILDLCTGSGCIAIACAYEFDEAEVDALDISEDALDVAQVNVETLGVMDRVFPMQSDLFSAIPEGPQYDLIVSNPPYVDEEDIGDMPDEYHHEPAIGLASGRDGLDLTKRILANAAQYLTPTGILVVEVGNSMVHLMEQFPEVPFTWVNFENGGDGVFVLTRDQLIEHQSLFAIYRDAQ
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Gr43a is the main sugar receptor in larvae. Functions as a narrowly tuned fructose receptor in taste neurons but also as a fructose receptor in the brain. Necessary and sufficient to sense hemolymph fructose and promote feeding in hungry flies but suppress feeding in satiated flies.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEISQPSIGIFYISKVLALAPYATVRNSKGRVEIGRSWLFTVYSATLTVVMVFLTYRGLLFDANSEIPVRMKSATSKVVTALDVSVVVMAIVSGVYCGLFSLNDTLELNDRLNKIDNTLNAYNNFRRDRWRALGMAAVSLLAISILVGLDVGTWMRIAQDMNIAQSDTELNVHWYIPFYSLYFILTGLQVNIANTAYGLGRRFGRLNRMLSSSFLAENNATSAIKPQKVSTVKNVSVNRPAMPSALHASLTKLNGETLPSEAAAKNKGLLLKSLADSHESLGKCVHLLSNSFGIAVLFILVSCLLHLVATAYFLFLELLSKRDNGYLWVQMLWICFHFLRLLMVVEPCHLAARESRKTIQIVCEIERKVHEPILAEAVKKFWQQLLVVDADFSACGLCRVNRTILTSFASAIATYLVILIQFQRTNG
The following text describes a protein:
Function:
Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions.
Miscellaneous:
MISCELLANEOUS: Marker of antero-posterior subdivisions of the somite.
Subcellular Localization:
Nucleus.
Sequence:
MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSAAAAAAAASVPFSIDGLLSGSCAAAAASVVNPTPLLPAACGVAGESQPFKLADSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQSRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPTAAAKGPGAHGSGIAGSAPVPPGEPPAPGTCDPAFYPSQRSGAGSQPRLGRPADKDTVPCGPGAAATAGLPKASPFSVESLLSDSPPRRKATPANAAATAGLDFTPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGPELVPKDAPPAPPAPPAPPAQASFGTFPGPGGAADPAFARRSPEVVASPGPPAPASFRDLTAAAAESGAGDCADVGTVCPAASPPPPLETSPGPGPRAPSPPGEPATCGAAEPGAATGPSPPEGEEVDMD
The following text describes a protein:
Function:
Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MWMNLLLAFLPVSLLLEYVFHAPPLWVFFTATIAIIPLADWLRQATEQIAERVGQTIGGLLNVTFGNLAELIIAIFVLLSGNAVVVKAQITGSIIGNALLGLGLAILIGSVGRQRQKFSWQNAGQLNSMLVLVTIALLIPALFDYTERLPGFAAGSDLARSDLDERLSLAVAVVLIAAYALNLVYTLVTHKDIFALDDGTEEGSAEGPAESTAEGAGHSHVAPWPVWKAVGVLVGATVLIAWMSEILSGALEATSQTLGLSPFFLGIIVLAVVGNFAEYISGSYFARQGKIGLAINIAVGATIQVALFTAPVLVLISYLIGKPMNLVFGSPLELVAIVAVAITVSTVTRDGEATWFEGVLLLTVYVLLALAFFFVTPRGEEGAPAALYAPAPALVQAAPERLALAS
The following text describes a protein:
Function:
Required for polarized growth and efficient budding; The M-Pol II complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins.
Miscellaneous:
MISCELLANEOUS: Present with 6280 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein.
Sequence:
MSSVPYNSQLPISNHLEYDEDEKKSRGSKLGLKYKMIYWRKTLCSSLARWRKLILLISLALFLFIWISDSTISRNPSTTSFQGQNSNDNKLSNTGSSINSKRYVPPYSKRSRWSFWNQDPRIVIILAANEGGGVLRWKNEQEWAIEGISIENKKAYAKRHGYALTIKDLTTSKRYSHEYREGWQKVDILRQTFREFPNAEWFWWLDLDTMIMEPSKSLEEHIFDRLETLADRELKSFNPLNLRDDIPYVDYSEEMEFLITQDCGGFNLGSFLIKNSEWSKLLLDMWWDPVLYEQKHMVWEHREQDALEALYENEPWIRSRIGFLPLRTINAFPPGACSEYSGDSRYFYSEKDHDFVVNMAGCNFGRDCWGEMQYYTTLMEKLNRKWYTRFFFP
The following text describes a protein:
Function:
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
Sequence:
MYTLIIPAAGQGKRMGAGKNKLFLLIDEVPIIVHTLRAFEKDKACKSIIMAINEEERPYFEELMQKYQIEKHVQFIQGGAERQDSVYNALQYASGVEYVLVHDGARPFVTNKVIRDVLTAAEKYGASICAVPVKDTVKKVEQGVVVETVERSQLNAVQTPQGFSVSLLLEAHRSAKQSCFLGTDDASLVERVGKQVGVVEGSYYNIKVTTPEDLLIAESFLRVQKK
The following text describes a protein:
Function:
Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSSKDIIGQKSAARKFTDNIKMTWSRLLDQTVPHRPLRWVMFVFMLSLYILRVYFCGGFYVISYVLGIHLLFLLVQVITPLADEDLGSEGQLPHTAASPDEEFRPFVPRMQEFVVWCSMMKSVLVCTFLTLFRILDIPVFWPVLLLYFIFLTIIQVGERIRHMIRHRYVPWSAGKPKFVPKS
The following text describes a protein:
Function:
Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
Sequence:
MIDLFRFFKSRAKTEEKEKLKELLKEKYSYFQKVLNSNNHVLSLMADLEEKLSGEYLFDMHYIKTSVQSISEGVEDIIKNLNALSDGKYKVLEQVQREIYENIEKTLTSKIDIPVTDFVIPIEKLSKDSLTIAGGKIAHLAELKNNLNLPTPDGFVITSYAFIKFLENTQLRGKISEIINSIDINKIEEIERGSREIQELIINSQLPEEIENSIRTAYKELSEKTGKKCMVSVRSSAIHEDSDYSFAGQYSTYLNVPENLISHYYKKVVASLFNRRAIFYYKTKGFSENEMVMAVGVLRMVNARAGGVMYSKNPNNPDSNNIIINAVKGLGKLIVDGAVNAETYVISRKPELKLIEKIPSKQNIMLICKEEGDIEEITLPNGSDEFSLEEQEALALSKIAIQIENYYESPQDIEWVIDEDGSIFILQARPLRILEKKTESKVYLPTRIKDYNILLDRGITACKGVGYGKAFVLKTEDDLQNFPEGAVLVAKHTNPRYVIIMNKASAIVTDIGSPTGHMASLSREYNIPTLINTEIATKTIKDGQEITVDATNCIIYEGKVEELIEAYKKTKEPFKETLLFKTLERVLKLIVPLNLVDPTSEDFKPEKCKTYHDITRFCHEMVMYEMFTMWDRYDSEHHAVPLIAGIPIGILVLDIEGGLKEGIKKATPEDVYSIPLQAILRGMQSMQWPGPPPVDAKGFFEMVAHTVSIPEEQLMETAKKSFCIVTKNYVNFSIRLGYHFSMIEAYTGENINDNYIKFFFKGGGAALDRRLRRVNLITTILKKMAFRVMVKEDVIDALLTKYSIPEIEKRLEVLGKLTAYTKQLDMVLFNDAIAQMYTEDFIKKHIKDI
The following text describes a protein:
Function:
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.
Sequence:
MKQDASRNAAYTVDCEDYVHVVEFNPFENGDSGNLIAYGGNNYVVIGMCTFQEEEADVEGIQYKTLRTFHHGVRVDGIAWSPETRLDSLPPVIKFCTSAADMKIRLFTSDLQDKNEYKVLEGHTDFINGLVFDPKEGQEIASVSDDHTCRIWNLEGVQTAHFVLHSPGMSVCWHPEETFKLMVAEKNGTIRFYDLLAQQAILSLESEQVPLMSAHWCLKNTFKVGAVAGNDWLIWDITRSSYPQNKRPVHMDRACLFRWSTISENLFATTGYPGKMASQFQIHHLGHPQPILMGSVAVGSGLSWHRTLPLCVIGGDHKLLFWVTEV
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNTFKIFRPIKILAEIFGLSPMTQKLTLSPLKVLQTVILGTTCIYLTSLYIWFILTQMTFSGVTSPTIMKFVLSFRTGSFTFLMVVAVLSSGTTFKLVAKTLENMTKIDKDLTELGQKKYLEKRNRHIFRTSVLLIFVMHLMFDTLGGLYSTWSKKSKQVEYFLIHWYPRMLISTKLLAHFLILTVLKARFEAINNIIDSIRQNSQTRNQAVPTGTIKTLVQMHSNLVTTSEEVCDSFSIFGLVWISLIFVVLIGDAYAVLNSVLFQNVYKPLPIVLSIVKNCLSYCFNLYHLASKSNQLSREAKVTKTVLLGVKIDICNEEERNSVVASVLQLMENKIEITACRLFNIDNALLFAICGSAFSYLFIMLQFDLNNKKNQSLGNGTTA
The following text describes a protein:
Function:
Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.
Sequence:
MSVKYFEPEEIVEHNNSKDMYMVINGKVYDVSNFADDHPGGLDIMLDYAGQDATKAYQDIGHSIAADELLEEMYIGDLKPGTEERLKELKKPRSFDNDTPPLPLLIALIVLPAIAVIVFVKLNK
The following text describes a protein:
Function:
Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Also modulates the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. In addition, stimulates T-lymphocyte chemotaxis by acting as a chemoattractant complex with PGLYRP1 that promotes lymphocyte migration via CCR5 and CXCR3 receptors.
Subcellular Localization:
Cytoplasm. Nucleus. Secreted.
Sequence:
MRVCILGYGMLTQGHCSLLSGCVFGASALHQPPGACLPPNPCFCHRTLPLPTLGLGHCFFPMQAPGQASSSPGRGRMGQGGAAVVAGSTGGAVGEAQPEGCCLTHTACATVLVLTATMTFPLEKALDVMVSTFHKYSGKEGDKFKLNRSELKELLMRELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYCVFLSCVAMMCNEFFEGFPDKQPRKK
The following text describes a protein:
Function:
Recognizes an AAGG motif at the MNF1-binding site.
Subcellular Localization:
Nucleus.
Sequence:
MKGAKSKGAAKADAKLAVKSKGAEKPAKGRKGKAGKDPNKPKRAPSAFFVFMEEFRKEFKEKNPKNKSVAAVGKAAGDRWKSLSESDKAPYVAKANKLKLEYNKAIAAYNKGESTAAKKAPAKEEEEEDEEESDKSKSEVNDEDDEEGSEEDEDDDE
The following text describes a protein:
Function:
Probable transcription factor required for superficial pseudohyphal development in response to nitrogen starvation.
Subcellular Localization:
Nucleus.
Sequence:
MDEMHSSDTLLLRTPKSKKKIGLVIPSTPSKKCKYSSGFIAEDTTPSKRFRLYQAKFKTSSKNVKAQTLSVSIKKNQGEITNPFMTEGYNDYRNIVSPGLSFDNDCFSEHELVSPLSDISSINSTSPDVEKIDSLDPFGVDSFVWNCKPLVNKEALELHRMIHSSFPMSPLESNSDVPLLLPKLKKRLSPVNRSTFKPTRYEPSHRLLKPKKSILTVPAKSLNLIVSSSRGSLNDATIFATEINSTLSNEENKLPAISSIWEKLTIPVNSSIKEKYKKLKDQIYGQASNFGEDEDNEEDNEDDLPDAAVIRGYEFQSGRRDELTQCNELQSTKDYKKVQWAKVLEQ