lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Subcellular Localization:
Cytoplasm.
Sequence:
MAEGQAPAPPQPEGDQECMCTQDKVLQFLNKMADESGIKDLTDPALAEFLTDSDALKGIRDLFHYPKAGTLPDVDPTLVDPNADSIYLCGNSLGLMPKVTEEVMKEHLDKWAKMGVFGHMTGEVPWAHSDEHCLEGVGRLVGAKKEEVSIANSLTVNIHVLLTAFYKPTETRHKILLESKAFPSDHYAIESQIRLKGRTVEESMVCMEPREGEETLRTEDIIDYIENNGDEIAIVFFSGIQYYTGQLFDIKAITEAGHRKGCLVGWDLAHAFANVPLHLHWWDVDFAAWCSYKYGCTGAGSIAGLFVHERFLHDKRDRMLGWWSHKMSSRFTMDNVLDLDEGAAGYRISNPPIHCVAAMLGSLKIFDQVSLENLRSRSCYLTGYLEYLVKTLFGENSEQRTTKLSILIITPENFHQRGCQLSLKFSSPIDVIYPELVKRGVAVDKRYPNVIRVAPVHLYNNYVDVRRFISVLQEVAHIVEDHA
The following text describes a protein:
Function:
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex cfd1-nbp35. Electrons are transferred to dre2 from NADPH via the FAD- and FMN-containing protein tah18. Tah18-dre2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit rnr2.
Subcellular Localization:
Cytoplasm. Mitochondrion intermembrane space.
Domain:
The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation; The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters; The twin Cx2C motifs are involved in the recognition by the mitochondrial mia40-erv1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.
Sequence:
MAPSFVSIDTTPDFDMTPTSSKSADSGKRTLLLAPPSIATQEDKLRTLFTTYDRSTTDLQMLDRVSAGFVSLPANTYDLVLVLTGTDGTRRSEALQLLKREVYAAVVPAMKGGAKLQTEDNFFGEAEDREAVLAGLVKKETGFEKMDVGNGAAVPLRLGRKKKAAPAPAPVVQPPPIISSDDNDLNDDELIDEDTLLSADDLKRPIVPPPECQPKAGKRRRACKDCTCGLAAQIEAEDRERREAADKSLNVMKLESDDLNELDFTVQGKTGSCGNCALGDAFRCDGCPFIGLPAFKPGQEVQILNDVAQL
The following text describes a protein:
Function:
DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MFDTKALQAEQRQRASEISLHDGIDNQSVRFIAGADVGFEQHGEITRAAIAILRYPSLALVEYQVARVATSLPYIPGLLSFREYPALLAAWAQLQQRPDLILVDGQGIAHPRRLGVASHFGLLVDVPTIGVAKSRLCGDFLPLHQDVGAVQPLFDNDEQLGWVWRSKIRCNPLFISPGHRVSVGSALAWVQRCMAGYRLPEPTRWADAIASNRPQFQRWLRKNPDFLGKRRDMI
The following text describes a protein:
Function:
Promotes plant growth, especially at the vegetative stage, probably via the regulation of phytosulfokine (PSK) signaling; PSK are peptide phytohormones acting as growth factors. Together with PSI2 and PSI3, required during vegetative growth and reproduction. May also have a function in carbohydrate metabolism.
Subcellular Localization:
Nucleus.
Sequence:
MGSFCSKSLGINFGSEYSGSSVADDGREPDFGHSQPNGQTSLIVPGMRQLMVKDVKEQNQLKDVFSFREREAEDNFYDGIPTYTMAPSQKIRSAKSTQTAVSKVTEASKLLGKAGLGRAKDVLDTLGSSMTDLSSGGFTSGVATKGNELGILAFEVANTIVKSSNLIESLSKRNIEHLKGTILYSEGVQNLVSNDFDELLRLVAADKRQELQVFSGEVVRFGNRSKDFQWHNLQRYFDRISKELTPQRQLKEDAVLVVDQLMVLVQYTAELYQELQVLYRLEKDYEQKRREEENSANSSKGDGLAILKTELKAQRKVVKSLKKKSLWSRGFEEVMEKLVDIVHFLLLEIHNIFGGADDQPSKKGAAEYDKRLGPAGLALHYANIIVQIDTLVARASSITSNARDSLYQSLPPGIKLALRSKIKSFNVDKELSVTQIKDEMERTLHWLVPVAGNTTKAHHGFGWVGEWANTGTDFTSKPSGGDILRIETLYHASKEKTEIYILGQIIWLQHLVTKAKSDARGGPRLSSIKSPLDTTNQQLISEPLSVPIVTDEEQKMLQEASKRKRTPCVSKSQDFDSEYSRARKCDPLSKSSEYFRGVRRSKSAAVKRYSSGFPLLDFAIDKEKVLDVIDRVDVPRDYKALLKEGSLSF
The following text describes a protein:
Function:
Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MEQVIALPYKWWAEAVTVWLIVAVVIYLIVAIPGIYFIYKYRYKPGEREIGDHDFEGHMGLEALLTIIPLLTVIFLATYSFTIFKKQRTVPDGAMTIKVTAFMWGWQFDYLDENGKVIKTVVTGYHANDYNLQEFEKPVIPAGKPIRALLTSMDVIHSFFVLPARITEDMVPGRTTYLWFQINKPGEYWVFCREYCGTGHSHMFTKLKVVPPEQFTAWLYGKNEVAIKSNNKEVAR
The following text describes a protein:
Function:
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
Sequence:
MGNSATDKAAVHPAPHEKIKTIEELGAVARAAQAEGRTVALCHGVFDLVHLGHVRHILAARNEADVVIVTVTADRFVNKGPGRPIFPENMRAEMLAALGTVDWVGINQTSSAEPILDTVRPDIYVKGSDYENPEDDVTGKIATEREAVERHGGRIVFTRDVTFSSSSLMNRYFDIYDPPLRDYLQKVREGGGAERLLKLIDKIQDMHVVLVGDTIIDEYQYVTALGKASKENIVATLLKNGEQFAGGVIAAANHVASFCKSVEIVTTLGGNDYPEEFIRAHVRPNVTLTPIRVQGRPTTRKLRYVELGYLHKLFEVYTMDDTPLDETERTEIDRITAERVRGGDVVIVTDFGHGMIAPSTIDTLIANSRFLAINAQSNSGNHGYNLITKYPRADYICIDAPEARLAATDKFNDIASVIENGLHRKIDCNNMIITHGSFGCYPFSSKTGVARVPAFTKTVVDTVGAGDAFLTITAPLVAAGGNIEDVAFIGNAAGAIKVGIVGHRNSVEKAPLVKFVTALLK
The following text describes a protein:
Function:
Involved in piRNA (piwi-interacting RNA)-mediated transposon repression. May be involved in formation of the perinuclear nuage, a subcellular structure implicated in RNA processing that may be involved in transposon RNA surveillance and silencing. Required for ping-pong amplification during piRNA biogenesis, probably by promoting transcription of piRNA precursors. As part of the Rhino-Deadlock-Cutoff (RDC) Complex associates with, and drives non-canonical transcription of germline specific dual-strand piRNA clusters 80F, 38C and 42AB, but not single-stranded piRNA cluster 20A. Induction of piRNA expression is potentially achieved through a mechanism that prevents transcriptional termination and leads to readthrough from flanking transcription units. Recruited to specific chromatin regions by a combination of H3K9me2/3 histone methylation and differentially expressed sequence-specific recruitment factors. This association may involve direct interaction with DNA. Associates with chromatin upon exposure to homologous piRNA and facilitates transcriptional read-through. As part of the RDC complex, involved in suppression of splicing. In ovaries, recruitment to specific heterochromatin clusters is nucleated and stabilized by kipf/kipferl. During oogenesis, involved in axis specification and may regulate chromosome condensation at the onset of a mitotic-like phase that occurs during nurse cell chromosome duplication. Involved in the distribution of mRNAs for proteins that play a role in anterior-posterior and dorsal-ventral axes specification during development of the oocyte, including grk/gurken, osk/oskar and vas/vasa. Mitigates meiotic double strand breaks and interacts with DNA damage signaling to mediate axis specification.
Miscellaneous:
MISCELLANEOUS: Wild-type eggs possess two dorsal respiratory appendages. Mutations in rhi/Rhino results in partial or complete fusion of these appendages resulting in a single appendage from which Rhino gets its name.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to germline specific nuclear foci throughout oogenesis, which corelate with dual-strand piRNA source loci. All components of the Rhino-Deadlock-Cutoff (RDC) Complex associate with these nuclear foci and are required for their formation.
Domain:
The Chromo domain mediates binding to chromatin through interaction with the histone H3 N-terminal tail. Binding requires di- or tri- methylation of histone H3 'Lys-10' (H3K9me2/3).
Sequence:
MSRNHQRPNLGLVDAPPNDHVEEYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEVFRLHRKAAAKSVGKSKSSPSSSGPLITENGPSSSKKTQQHSKSVQAKNTAGMSKMNQKKGKNIKKTAGKIKDIENYPKTQMPSTSQVSTDSTEVFDGNPSATTTNMIKSPRIQSLFSDLNLIEPTKDKDVGDTSLKTPPKSRRLIEFPQREDAPLSSKHVSPMLIRKESQPLQSSCTDDSDLGESSSSMSLPTVSSTSSEKSIKVTKSEPKTLGQIKFSSRSSDGGHAASSLGAPKEGDIGLDLSGSDSMDSEVESMRRCPRRKRKKTYPDWKFPEMTKPFGVNRGLDLDKILHCYQMNDDLFMFVTWKGCSSIDAVHINDIKEAYPLQIIKYFESLRIIVPK
The following text describes a protein:
Function:
Involved in RNA editing event in chloroplasts. Required for the editing of a single site in rps14 transcript.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MEYAVTNMRLLSNMMYSASAISFPRVRLHCSIPTEPSCRRNPFRQSNQPVQVPSPKLACFDGVLTEAFQRLDVSENNSPVEAFAYVLELCGKRRAVSQGRQLHSRIFKTFPSFELDFLAGKLVFMYGKCGSLDDAEKVFDEMPDRTAFAWNTMIGAYVSNGEPASALALYWNMRVEGVPLGLSSFPALLKACAKLRDIRSGSELHSLLVKLGYHSTGFIVNALVSMYAKNDDLSAARRLFDGFQEKGDAVLWNSILSSYSTSGKSLETLELFREMHMTGPAPNSYTIVSALTACDGFSYAKLGKEIHASVLKSSTHSSELYVCNALIAMYTRCGKMPQAERILRQMNNADVVTWNSLIKGYVQNLMYKEALEFFSDMIAAGHKSDEVSMTSIIAASGRLSNLLAGMELHAYVIKHGWDSNLQVGNTLIDMYSKCNLTCYMGRAFLRMHDKDLISWTTVIAGYAQNDCHVEALELFRDVAKKRMEIDEMILGSILRASSVLKSMLIVKEIHCHILRKGLLDTVIQNELVDVYGKCRNMGYATRVFESIKGKDVVSWTSMISSSALNGNESEAVELFRRMVETGLSADSVALLCILSAAASLSALNKGREIHCYLLRKGFCLEGSIAVAVVDMYACCGDLQSAKAVFDRIERKGLLQYTSMINAYGMHGCGKAAVELFDKMRHENVSPDHISFLALLYACSHAGLLDEGRGFLKIMEHEYELEPWPEHYVCLVDMLGRANCVVEAFEFVKMMKTEPTAEVWCALLAACRSHSEKEIGEIAAQRLLELEPKNPGNLVLVSNVFAEQGRWNDVEKVRAKMKASGMEKHPGCSWIEMDGKVHKFTARDKSHPESKEIYEKLSEVTRKLEREVGYVADTKFVLHNVDEGEKVQMLHGHSERIAIAYGLLRTPDRACLRITKNLRVCRDCHTFCKLVSKLFRRDIVMRDANRFHHFESGLCSCGDSW
The following text describes a protein:
Function:
Required for normal Golgi function.
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MDVSALSETTFSPAEWINANYKKFVEENGRDDSEAASAFIRSYVAKLQLYIFNVNNAVEESSRQVVASMPRIAKESAALQADVHRLQEKMSAMRLEVAAVQSETGECMATLERLNTKSQKLQVAKESLQESDGWGNLLAELEDGFERNDLKGVCDKLIALQKSLHAQEQLPGHAERQTQVEDFKNRLEALASPSVVQCFAEGNTEQAQHFVQIFTSIQRLPQLQQYYRAVQKNFWQQQWKQTLELQGTESQPQQQQFLTLYYDQLLEHCQRQVKWCSNLFGENSPQPFLVIAELLPALQPTRDAHILQLLKTSNERLEMLALFAKVNHSFVLHLNSLLEQSHITLSEELHRLLGEAIFEYFHKFIQQYPRLEETQLSTQVDRLSSNQATPSDGVRHLEESTRKLYEWLKEACERCASITSDLALCKLITLLNGIFKRQLESFGRIQRQIGLSLGSSSYAAQSENWSLLQYTMSQLQCLADFQVQLHQFEQDLHTRMVMLSNRLTKPSNRGPITIFQTCDHAARTQLLNSIADYQQKKSEATDSLGIFPQIYATLKSHFADTHDITLNILLQPIETHLAHIRPPVQDHAASGIEMPSFSFAPQESITQIGQYLLTLPQHLEPLLLSPSSLLKQALEVCNIKYTQAIPCADVLLSLVVEQCCVLYVTQILQIKSLPSSAATQLSVDIEYLSNVLEELGLSINLQLSQILTLLKAAPDQYLTLSSGCEPRLVTAIRQMRNIISTQ
The following text describes a protein:
Function:
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
Subcellular Localization:
Nucleus.
Sequence:
MNCKEELAGLCRQAGRQAGRPHIPFNFQLHSFHINVNVSSSPLGFLSTVCGVMRQSNREVGMISVKGVPHALPLARIKKIMKRSGEDVRMISGEAPIVFAKACELFIEDIAQKSWNLTLRGKRRTLHKDDVAKAINATDVFDFLIDMVSSHQSNTHPQPTSNVLQR
The following text describes a protein:
Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Sequence:
MAEPGEGLPEEVLALIFRHLSLRDRAAAARVCRAWAAAATCSAVWHDTKISCECELEGMLPPYLSACLDHIHNLRLEFEPSRKPSRRAAIELLMVLAGRAPGLRGLRLECRGEKPLFDAGRDVLEAVHAVCGAASQLRHLDLRRLSFTLDDALVLQAARSCPELHSLFLDNSTLVGSVGPGSVLELLEACPRLRALGLHLASLSHAILEALAAPDRAPFALLALRCACPEDARASPLPNEAWVALRRRHPGLAVELELEPALPAESVTRVLQPAVPVAALRLNLSGDTVGPVRFAAHHYAATLCALEVRAAASAELNAALEELAARCAALREVHCFCVVSHSVLDAFRAHCPRLRTYTLKLTREPHPWRPTLVA
The following text describes a protein:
Function:
Probable GPI-anchored aspartic-type endopeptidase which contributes to virulence.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MRHIFSLLSIVCLMVKHGACLTLHQRDVPAVVSLDIKRSIVSDPVVRDRVRRKRDKTIGQTLDNAETLYFCNVTLGTPGQALRLVLDTGSSDLWCNAANSTLCSDSNDSCNISGSYDPSSSSTYAYVSSDFNISYADGTGAVGDYATDILHIGGSTLRNLQFGIGYSSTSSEGVLGIGYPSNEVQVGQYGKDTYPNLPRAMVDQGLINSNAYSLWLNDLESNTGSILFGGVNTGKYLGELQTLPIQKVNGRYSEFVIALTGVAFDSESHHKTYSSDALPAAVLLDSGSSLTYLPDSIVENIYRDLNVAYEPSSGVGYLPCKLAGNNINITYTFSSPNITVMIDELLLDAGDLRFRDGARACIFGIVPAGDSTAVLGDTFLRSAYVVYDIANNEISIANTNFNSTEDNILEIGVGPDSVPSATQVSHPVTSVVADGSGARIGAPTGASSTTVPSISSAGALSAGVARADKQYLAIALIAVWFVLGL
The following text describes a protein:
Function:
Regulates dense-core vesicle (DCV) trafficking and/or secretion. Probably by controlling DCV trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Involved in locomotion by regulating acetylcholine release. Probably by controlling the secretion of FLP neuropeptides, regulates the turning step of male mating behavior. Plays a role in preventing dauer formation.
Subcellular Localization:
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, axon. Cell projection, dendrite. Note=Localizes to dense-core vesicles along axons.
Sequence:
MRFFHSIIVLLFSISTGSAFLLYGCNLSENLCDNDESCYPDGVFGQCYSSESGSPEPTVLDNLDDTQLELLKLELTRLAAKDKDWGDEETQCVLAYFKMSMFYQLQYDPDFCQVRKPANVWALIQLIDTGLTEDPTILDEDVNPENVTDEDMAQIIEQLKEPSLPTEEDIEEALNAQNEDVDDEILDQYVQAVVNNENPDFSELSDGQLNILIGRLVDLKKNVENEEAQLLTGDGEQEMAVPLDDLEERGEQAILKKDIEQVGEINQGLDNTEHKIVKGRKDQVVTRVDANRVYLKVHLKNEDQLMPLIEFLQNTIAIPNNLYFDDFQFENGQLSMRISRFEGAKPKADKRIDSVEGVASAVYKRRKDIARLSGADVRETGIGSGEDGSLPVESSERDWLLMPVLFVCAFTVTALGLVAAVQIARSRRHYKDNIQQIAEQLDGKNSFAYQDLCRQRADGGRASKSSSTSSWCEETAVPTIDISTGHVVLNFLQEYLSEPTKIEAQWNGIKDYRNEERTKTKAEKFASQNRTILPFDDNIVDIDGKTAENEDFYLNASFIYDDDPRQAVYIAAQTPASSQIAAFWQTIWQHGVCLVVNLSTPEECKQEKNYWPDTGSEVHGAFEIHLVSEHIWSDDYLVRSFYLKNLQNSQTRTITQFHYLSWQKESTPTSAKSILEFRRKVNKSYRGRSSAVLVHSWDGSGRTGVYCAVDVLCARLLRGIRQIDVVATVEHLRDQRDGMVATGDQFKLVYGCVAQEVNHLLKSIATK
The following text describes a protein:
Function:
Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
Subcellular Localization:
Cytoplasm.
Sequence:
MFQYVSDEASLNALVAQYQQSPLLVLDTEFVRTRTYYAKLGLIQAYDGKTLALIDPIALPDLSAFWALLDNPNIIKLVHSCSEDLEVFAHYGQRQPTPLFDSQIAASLCGMGHGLGYAKLVETCLGEVIDKGESRTDWMRRPLTDAQLSYAANDVLYLYQLYPQLAEKLQTQDRLDWLYEEGERMTEGRLASPDAETAYLKVKNAFQLTEHQLAYLKVLAKWRLEKALARDLALGFVIKDHGLIALAKKQPKSMSDLLKLNDLTEQEKRIHGKDILRVMQTADLSNPPELVDVLALKPGYKSAFKTIKTSLTELCEQHAILMEMLGSKRHIHEYLQWRWDKQQGELPTVLSGWRGEIAAESLAKLEV
The following text describes a protein:
Function:
Plays a major role in organizing microtubules and spindle poles during mitosis and meiosis in one-cell stage embryos. Required for default nucleus positioning in oocytes.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Note=Cycles between cytoplasm and centrosome during mitosis in a cell cycle- dependent manner. Centrosomal recruitment requires tbg-1.
Domain:
The TOG (tumor overexpressed gene) domains are arranged in the N-terminal region with each domain composed of six (for the most part non-canonical) HEAT repeats and forming a oblong paddle-like structure. 3D-structure analysis shows the presence of additional HEAT repeats that are not detected by sequence-based prediction programs. Intra-HEAT loops are positioned along a face of the TOG domain and bind to a single alpha/beta-tubulin heterodimer. The TOG domains seem to be structurally and functionally polarized. Differential functions may range from microtubule (MT) lattice binding and/or free tubulin heterodimer binding to potentiating stable incorporation of tubulin into the MT lattice.
Sequence:
MSNWDYLDEVDILPKLPPNFDELRESKKWQERKEALEALLKVLTDNERLSTKASYAELIGHLQMVLAKDANINCQALAAKCIGKFATGLRAKFSSFAGPLLPVIFEKMKEKKPMLREPLVDCSNEVGRTMQSLETGQEDILAALAKPNPQIKQQTALFVARQLDLVVPAKQPKGFIKAVVPVFGKLTGDADQDVREASLQGLGAVQRIIGDKNVKNLLGDASSDEGKMKKIGEYAEKSTASFAEEQAKNAPPVAPTSSTPSASAASGDPSGGTATAVVSSGAPVAEADPWDFLDAFDVLSKMPDGFDTNIESKKWQERKEALEGLLQLITANPKLDPKANYGALVERLQKVLEKDANINVAALAANCITGIANGLRTKFQPFAVSVTPIIFEKFKEKKPTLRDPLVACIDAVVATTNLEAVGEIVLAALGKPNPSIKTQTDLFLQRCFMKLNSQTMPKKTLKTLIPSLIKHSGDSDSEVREASYAAMGAMMRAIGEKPSLQLLADIASDNLKMSKIKEFHQKALDEAGPAEIAEMVKSIHKADAPPAAAPPKKTAPPKKQPEDEEVVEEEDEPLKPPPGDKKKKVPVKENEENEPPVVAPKAELLLSDNEDKKQRIKEEKQLKLVKWNFQAPTDEHISQLQTLLGNQAKVSLMSQLFHKDFKQHLAALDSLVRLADTSPRSLLSNSDLLLKWCTLRFFETNPAALIKVLELCKVIVELIRDTETPMSQEEVSAFVPYLLLKTGEAKDNMRTSVRDIVNVLSDVVGPLKMTPMLLDALKSKNARQRSECLLVIEYYITNAGISPLKSLSVEKTVAPFVGDKDVNVRNAAINVLVACFKFEGDQMWKAAGRMADKDKSLVEERIKRTGVKPGSGVVTSPPTGGPKILVPQQQGSVVRRPASRSRTREPEPEEVQSDTFTIRQDTMPPKTSSRYALRDDVFSSAMGRLDGTQVITPPQPVNGWSNNTFQMKRTNSSSSISSIDTSDQIQRSINNISSSLADVAQDAMFQVTYVLNQPEQRHLVDRRADLVFRASAAQLDLVIEEFNAGRDVSGTMDACTQMLFILMGGVETEHGLEPLNASPDTVKAIISSVLRCIIQIGNTESGYGMARSLNRLAMRLIYRVELSNLLCGLILAMTESLQMNTGITELVSKLSSKWCDELEKRRAQLRASDIVDSFNAFYVCALTELKMDISDSHILIVDNYLERVILQQGDVVLDAARRLSRPHMHLTSMINKILQMMRERKIDPIMPGTLEARMPQEDEAVVVRSGVQVSIDNILRDTSMAVKHIEQLNILIASSDRSWNEYMEYLKNNPMGELIKELVGECSRKKRIDFNLSHVVKSSMAVFKAMAATGPVQEEGRITPTDINRMDTMIVGTPLSRGDATITRARGNMIRPKRTTLSRDQMANIRHTLDRVKNH
The following text describes a protein:
Function:
Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces.
Miscellaneous:
MISCELLANEOUS: The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.
Sequence:
MKKKTIFQCVILFFSILNIHVGMAGPEQVSMHIYGNVVDQGCDVATKSALQNIHIGDFNISDFQAANTVSTAADLNIDITGCAAGITGADVLFSGEADTLAPTLLKLTDTGGSGGMATGIAVQILDAQSQQEIPLNQVQPLTPLKAGDNTLKYQLRYKSTKAGATGGNATAVLYFDLVYQ
The following text describes a protein:
Function:
Receptor tyrosine kinase which may phosphorylate mlk-1, a component of the mlk-1, mek-1 and kgb-1 pathway. Involved in axon regeneration after injury by promoting the generation of productive and stable growth cones.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MVLGSSQSSAKELTTQSSIFRFLVLLLCFTSATGGQINGKLLNGNGVFVSRDELQNKNVLGVITGFDLLVVATHSRFQVFENNEERRTVGHVSLDMHPRTKFLELKLFSKSEIFYCDESSCGLCTYSGVTSSCSTFMLNGDEPKIQEILSSSAVKIENLGQIMLAISFKNEEDPDNPRTMILRYNAQDTGTVIPTAYHADSSFIHNNHALTGFEREGFVYFVMTASQIFEPEVFLHDQSNNKVTVTKVIRFCATDQTADLASKISILVGCDQEFRNISSRGETAVYDHANDLINIVMFNHTSMNHLMCRFKMANIEKRFKTIWSTCQETSFSGSTAKTTRCKYPQIFDQMKVKKGCLTYSRLDDESSPTLCVRYGRGDALDNCQLHTAKSNSYRYGWLEDYNVLQGELMMRIPYPFFGIAESLITDGKSYFAAVSGEFDMSDVLRFSASESADIRPHWRTNISVVGKFSITKTKENQLLYTTVEGLQSLDISCKGLYPNCQTLRQGGWEDPLECSWCADDNAQRTITSSEVSSCKNNLKHECPPSMRWIHKYNNNSGFTAVVDGFRALKNPKLNACGTNCVVTVVDSSSIQCDTNPDEVIGDSCKQVFLSGMIGDKNYSFPFDYQQADRGTQTDVKNSQVDDKKGSSPGWKIAIAIISVMTIILIVAIIVYYMRNRFPRIKTHVRPPIGQRIENEYDMGHMAGRQAQLAINGDNYVKVFRSMRPDLKVDFKNLRVDKLDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPIIITEYMAKGDLKSFIENVENTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPEISEQGFGITSDIWSFGVVIWELFTRGSTPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTIIPNVVKYMEGYDRSQLQAGYERVSSRFLSLSRHDPAFPIYQNEMPNTPLLANCQNDTNDSKTLAELPSDSPSTSTAIPQSTPYQLLSECSETSV
The following text describes a protein:
Function:
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.
Subcellular Localization:
Cytoplasm.
Sequence:
MTLPSNTLILDNGAYTIKAGFPNDECLSIPNCLCRSKDGNRLFLGDEISVCKDFSSLQFKRAHEKGYVTNWSTEISLWDQTFQRLGIQDQKMNGHSLVLTEAPFTMPSIQMNTTQVVFEEFEFDSLFTGLPAEFVAWNDLRSAFKEPKEWGAYKDCVLVIDSGYSFTHIIPVMNGIAMEQGIRRIDLGGRFLTNYLKEIISYRKFNMMKDFYLVNEIKEATCFVSQNLKKDMEMGRRLRRNPLQMFYALPDYSSGRMGGVISSTSAADAREQQILGLCTERFVTPELLFSPSDIGMHQSGIPETVMQSLEQFPEDLAALFLANIVLVGGNVKLPGFRTRFEAELRALAPSTAQVRSYLPKDAITFAWQGAGSMPMEFFQLGSVSRHEFAEHGMNVFRRKKMSLRLDAHK
The following text describes a protein:
Function:
Axoneme-binding protein that plays a role in the regulation of ciliary motility and cilium length.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum basal body. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Note=Present all along the flagellum, with a marked signal at the base of the flagellum.
Domain:
The conserved TPR domains are dispensable for ciliary targeting. The N-terminal half is important for cilary localization and/or binding to the axoneme.
Sequence:
MEQVPSAGRLVQITVTEGYDLKGFKGDTPVTFIRAEFNQVVLGDSAKITVSPEGSAKYNFTSSFEFNPEGGITSDDLAHKPVFLTVTEVLPKEKKQKEEKTLILGQAVVDLLPLLEGQSSFQTTVPLHPVQGSPLETPRSSAKQCSLEVKVLVAEPLLTTAQISGGNLLKVTLEAAYSVPESFIPTGPGQNYMVGLQVPSLGEKDYPILFKNGTLKLGGEREPVPRPKKWPIANILAPGANNIPDAFIVGGPYEEEEGELNHPEDSEFRNQAECIKKRIIWDLESRCYLDPSAVVSFQKRIADCRLWPVEITRVPLVTIPKGKAGKTEKTDEEAQLSFHGVAYVNMVPLLYPGVKRIRGAFHVYPYLDSVVHEKTKCLLSLFRDIGHHLIHNNKIGGINSLLSKQAVSKNLKEDKPVKEKDIDGRPRPGDVQAPSIKSQSSDTPLEGEPPLSHNPEGQQYVEAGTYIVLEIQLDKALVPKRMPEELARRVKEMIPPRPPLTRRTGGAQKAMSDYHIQIKNISRAILDEYYRMFGKQVAKLESDMDSETLEEQKCQLSYELNCSGKYFAFKEQLKHAVVKIVRDKYLKTTSFESQEELQTFISELYVFLVDQMHVALNQTMPDDVQGTVATIYTSSEQLQLFAFEAEVNENFEMAAAYYKERLVREPQNLDHWLDYGAFCLLTEDNIKAQECFQKALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEASKQLQARMLQAQVTKQKSTGVEDTEERGKRESSLGPWGITNGSATAIKVEAPAGPGAALSILDKFLEESSKLQSDSQEPILTTQTWDPSISQKPSNTFIKEIPTKKEASKCQDSSALLHPGLHYGVSQTTTIFMETIHFLMKVKAVQYVHRVLAHELLCPQGGPSCEYYLVLAQTHILKKNFAKAEEYLQQAAQMDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSPSCLTWLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLKLKDEALLAEIHTLQETVGFGNPSF
The following text describes a protein:
Function:
DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs.
Subcellular Localization:
Nucleus.
Sequence:
MQNRPYKTWKALVDKMETVKGMSPTLLNGAKNVLHMRGVVSRLMSKCQGIADRMQEIVSQLVSGSEESEGYIKEQPSTLNNSLQLSPYQLIGLNWLAVMHKQEVNGILADEMGLGKTIQAIAFLAYLQQQKENGPHLIVVPTSTLENWMRELQLWCPSLDVLVYHGSQEDRRELKYQILDGEVGTFHVLVTTYHMVSGSAEDRSLFKKLPFNYVIFDEAHLLKNMASQRYNNLMKINAQRKILLTGTPLQNNLVELMSLLTFVMPRMFSNKAEQIKLMFTSAAVSRTGTHRFERERVAHAKKIMRPFVLRRLKRDVLQQLPTKHEEERLVPMTPYQATCYTNLVAALSKEFQEKQEARSGIHMMMKLRRAANHPLLLRVHYNSDKLRTMSTLMLKERTHHDANPDLIFEDMEVLSDFELHTLCTKYQSLRDYRLEDDLIMDSGKFRELDSVLSDSLKKNHRVLIFSQFTMVLDILEAYLNIRGHKWLRLDGATSVTDRQDLIDKYNGDSSILAFLLSTRAGGQGINLASANVVVLHDVDFNPYNDKQAEDRCHRLGQSRDVFVIKFVSKDTIEEGILAIAKEKLKLEKDITEETVNEDMDSISVAQLLKSALGN
The following text describes a protein:
Function:
Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for replication and persistence during infection of mice.
Sequence:
MIFKVGDTVVYPHHGAALVEAIETRTIKGEQKEYLVLKVAQGDLTVRVPAENAEYVGVRDVVGQEGLDKVFQVLRAPHTEEPTNWSRRYKANLEKLASGDVNKVAEVVRDLWRRDQERGLSAGEKRMLAKARQILVGELALAESTDDAKAETILDEVLAAAS
The following text describes a protein:
Function:
Not known. A homolog of ribosomal protein bL25, it is missing the N-terminal domain which binds 5S rRNA. In vitro does not bind 5S rRNA.
Sequence:
MPHGEAFLIEAELDGETRVCLLKDIQFGWLGNNPIHIDLYDLSNVEEIEVEVPIEFVGTPAGVEAGGTFEPVMHTLTIKAPPAKIPEKIVVDVSGLGLGEALHVRDITPPEGCMILDNPEETVAVVYEPEEEVIGEEETGAEETGETEATS