lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis.
Sequence:
MAIVQTLPVPLEPAPEATTAPQAPAMGSVSSLISGRPCPGGPAPPRHHGPPGPTFFRQQDGLLRGGYEAQEPLCPAVPPRKAVPSTSFTYINEDFRTESPPSPSSDIEDAREQRARNAHLRGPPPKLIPVSGKLEKNMEKILIRPTAFKPVLPKPRGAPSLPSFLGPRAAGLSGSQGSLTQLFGGPASSSSSSSSSAADKPLALSGWASGCPSGTLSDSGRNSLSSLPTYSTGGAEPATHSPGGHLPSHGPGRGALPGPARGAPTGPSHSDSGRSSSSKSTGSLGGRMAGGLLGSGARASPDSSSCGERSPPPPPPPPPPSDEALLHCVLEGKLHDREAELQQLRDSLDESEVTVCQAYEERQRPWPREREALRDDGFTQAQRAQRAQQLLQLQVFQLQQEKRQLQDDFAQLLQEREQLERRCATFEREQRELGPRLEETKWEVCQKSGEISLLKQQLKESQAELVQKGSELVALRVALREARAALRVSEGRARGLQEAARARELELEACSQELQRHRQEAERLREKAGQLDTEAAGLREPHVPPATADPFLLAESDEAKVQRAAAGVGGSLRAQVERLRAELQRERRRGEEQRDSFEGERLAWQAEKEQVIRYQKQLQHNYIQMYRRNRQLEQELQQLSLELEARELADLGLAEPSPCICLEEITATEI
The following text describes a protein:
Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Sequence:
MSEQQPLPTLPMWRVDHIEPSPEMLALRANGPIHRVRFPSGHEGWWVTGYDEAKAVLSDAAFRPAGMPPAAFTPDSVILGSPGWLVSHEGREHARLRAIVAPAFSDRRVKLLVQQVEAIAAHLFETLAAQPQPADLRRHLSFPLPAMVISALMGVLYEDHAFFAGLSDEVMTHQHESGPRSASRLAWEELRAYIRGKMRDKRQDPDDNLLTDLLAAVDQGKASEEEAVGLAAGMLVAGHESTVAQIEFGLLAMFRHPQQRERLVGDPSLVDKAVEEILRMYPPGAGWDGIMRYPRTDVTIAGEHIPAESKVLVGLPATSFDPHHFDDPEIFDIERQEKPHLAFSYGPHACIGVALARLELKVVFGSIFQRLPALRLAVAPEQLKLRKEIITGGFEQFPVLW
The following text describes a protein:
Function:
Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin-remodeling complex.
Subcellular Localization:
Nucleus.
Sequence:
MADVESAGVDDSFAQSEPHDEQQIHNMTVGTRRQPNGTIGSVYSGNKIRHLKKEDGIPLWRKDIQYQFLKLVFEDKTPVFTRWPDGQKNMDFADIYIDAMARSSKTSKILKDKLQSDKQAAINMAMVCLLVNFGRMNTTLNFFPEMRAQLRTYHSIPSLQAHQDPNAYKQLQDAPRLKSILKGASEDVDQPNTLDKIKRENVPRTNPVNLIFVLAQYAPKVSEMHFFPPRDFFDLVMRSTLSSKSRAKAFLWLMWWYLESDFSREAALNNPFGPGLEGEGTGGLPIKVPSFEILTEEQANEENVDTQSEIEYGEEKRLERKRILEEEEPTPRAPKRPKKMPYWEFQYLKQMEPGTKIPSRQFSNKGDAYRAAADSDDLIEFRNPDGSIRSTLKMPRDEDYAYQSGSLDGPSPRIVLRTKAENTPDAASPAPPGSGYPILNRFVTEASPHHQGSSRRPRPLTQHQLAVERNRRQRIEYILAKRKGEAYRLLRAKRLTEIPFARYGRLLQNLPDGYDTDDDKSWGKGGLLPNPEEEEDFGECANYFLSVIRKASRRLDRWDYEHANGPRRDRKKEREERQKAREEAMDFDGDVDGKVSSRSSRARAQRNAKRKLARAAAAASSTPSASTPKTAAARSKGNRSRNPRDEKVAAATSLGANTGLETPSRDDALSPVQGDLEGEESLDDIDRELLGEGSGDEDDIPPRGLEPSRPAELGYDDSFLGGDADDALSSDEEEEEAEDEELDEMDVEGDDNLSAPGGEGRYAASDVSGPEMANGKPGWN
The following text describes a protein:
Function:
Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
Sequence:
MTAAFPPLSPELGQLALDRAAQGERLGADELESLYHLPLPAVAAVAHDLRMQRRDPDVVSFLIDRNINYTNICNVGCNFCAFYRTRRQSDSYTLDYEQISAKIRELEAVGGTRILLQGGVNPELGLDYYTGMLRHVKAHHPTIQIDAFSPEEVLFMEKSFGLSLDDLLDTLMDAGLDGLPGAGGEILEDDVRQKAAPARIRSGDWFRIIDAAQRKGLYTIATMVIGFGETYAQRVSHLLKIRAQQDKAQREYGGNGFFGFALWTLQTEHTRLHGKAPGATAHEYLQQLAVARIALDNLPNLQASWPAQGFKVGQAALYYGANDLGSTMLEENVVSAAAGHDRHAATVRELIRIAVDAGFTPAIRNSRFEILSYPDVDAALGRLAANPEAERGVGAN
The following text describes a protein:
Function:
Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
Sequence:
MINSRQNYLNAKRFSADLALEHIIPHNVCFYLIPPIVDLTIDEFEKLALERLKMLRLLEQVTAKNPKVSSEAWREAVLAEVNHEGLRTYAKLARGNLNDDASKAARRRDYLSHFILRFAYCRSEELRRWFVAREMELFRLKFGALSMRDVKDFLEVYELDYKPLSDEEKLDISEHLCASTYNHTRLKMETTDFYAVHFTEVLNLVRDRKCFLKAGVAYITPEHFAHVIGKKHQQLIEDGLKGHLRLLPTLEIDERFAMLLKSIHTSYTGKNYTVAKTGSVPVESLDQLSKKSFALCMRNVHDTLRATHHLKHVGRMQYTLFLKAIGVTMEDALRFWREELTRGKVPIEKFEKEYAYAIRHNYGKEGSRINYSPFSCMKVITTPIGPGETHGCPFKNLDSSTLKMKLTGYGLSAIDADEVAGYATKGHYQIACGKYFEVVHETKLEEGINHPNQYFELSQLTMEGKERPRQGPANQSARWNSQPNSQSTQDGGMVGDSSTLNGADDDLELWEIMESKEKETDADGTMLAVPVAESLSKKVSPKQTKAAQEWDDDDFDMLEFNE
The following text describes a protein:
Function:
RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MARKRRQRGKRHSSKKTEDVDVSEDEFEQTEEPKLGQINKYTKEPIQPFLGVLTPEEEKYFREIEETLVSHNTRDNEDTRYLVDSIFAEVSGKELQVLNNVFGSKVLEKVFTLASSQQIKNFFGALNGSYLQITQTTFGSFVLEKLLSHMGRIIDMEEKGGALDEEEGSEFVATAESLIMYMCNELRPEISALLDHKLAAHVLEKLLLLLNGQRSVQEGESKAKYVSISVPSSFKEYAYSIVESAAENLEATELRAYSVNKYASRVIQAFVRIEFERRARSKKNKATPFSDKLLLSKEYDWKELPFVETLLKDETGSRVLEVLVERMPASDLTRLENVFEGRYYRLCVHPIANFVMQKFIKRANALTVERMLNELKDSSESLVRKSFLSVLKTLLETCNEKNFHQNHLFRLIISAAKERHPKQNLFVALLRSKHKKDKNSTDGKRVLVNNFIAVQLVEEMLRVPIELSSELIESLLELEPESIVEYATETASSHIIEQILGMSDLKMAHRRRLLNAFDGHFAEIAVTAPGSHIVDKCWFATQDLPLYRSRIVAELAEAGDEVKFDFYGKKVWANWKVELYRRAADQWYRWSKEDKSEKPIMKRVRSLPPLENTFARKRTMEPSEDLGASKKTRMTAFFGTI
The following text describes a protein:
Function:
Removes the phosphate from trehalose 6-phosphate to produce free trehalose. Trehalose accumulation in plant may improve abiotic stress tolerance.
Sequence:
MDMQMYRGHAVVAALVLLTTVTAASPTGYWGYLCDGGNYSAPSKYQQNLEQLSATLPEAVASSPTLFHTQAVGSSHDRAYALARCRGDTEADDCRRCLTQAFQDARAVCTFRKGISIYYDTCSLWFAEKKIKIHLGDSQSVLRADGPPIPTQCKAFQNDASTLIADVARKASDSSQRYATGEKGRDERACNYTLYTLADCLPGISAAQCQVCLEDLTSTPGLSGGQMGERKATLLCSYRLEPYQFFRDTKGHKNKTVWIVVGVAGGAVLLAIALLLWWWLLAKRPSAIDSFNKITANWQGKTIALFLDYDGTLAPKVDNPDEAYMSSEMREVVQELASLCATSVVSGRARYKTESFVMIENLHYAGSHGAEIKLIDETEAYEPAREYVPVINQARERLEEAIKEIKGASIEHKKFGISVHYRCVEEEEQELVKKLAKQTIKGFSELTVTKGDKVVEVRPKAEFNKGFAVKYILEQLARKNNWDSSQVVAIFIGDDKTDEDAFKVLWKRVGGLGILVNKKRKWTKASYSLEDPAQVQKFLQMLLSWKKKAEAEV
The following text describes a protein:
Function:
Its capacity to bind DNA and protein(s), and its differential expression during development suggest a role in the regulation of gene expression during Drosophila development. It could, in interaction with other factors, be required for the translation of instructions provided by pattern forming genes and controls, via chromatin changes, the activity of genes critical for the process of morphogenesis of several embryonic territories.
Subcellular Localization:
Nucleus.
Sequence:
MAQKKAVTVKGKKATNGEEKPLAKRVTKSTKVQEEETVVPQSPSKKSRKQPVKEVPQFSEEDESDVEEQNDEQPGDDSDFETEEAAGLIDDEAEEDEEYNSDDEEDDDDDELEPGEVSKSEGADEVDESDDDEEAPVEKPVSKKSEKANSEKSEENRGIPKVKVGKIPLGTPKNQIVFVTNLPNEYLHKDLVALFAKFGRLSALQRFTNLNGNKSVLIAFDTSTGAEAVLQAKPKALTLGDNVLSVSQPRNKEENNERTVVVGLIGPNITKDDLKTFFEKVAPVEAVTISSNRLMPRAFVRLASVDDIPKALKLHSTELFSRFITVRRISQESISRTSELTLVVENVGKHESYSSDALEKIFKKFGDVEEIDVVCSKAVLAFVTFKQSDAATKALAQLDGKTVNKFEWKLHRFERSTSGRAILVTNLTSDATEADLRKVFNDSGEIESIIMLGQKAVVKFKDDEGFCKSFLANESIVNNAPIFIEPNSLLKHRLLKKRLAIGQTRAPRKFQKDTKPNFGKKPFNKRPAQENGGKSFVKRARF
The following text describes a protein:
Function:
Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
Sequence:
MPKEDRATWKSNYFLKIIQLLDDYPKCFTVGADNVGSKQMQQIRMSLRGKAVVLMGRNTMICKAIQGHLENNPALEKLLPHIRGMWALCSPRRTSLRSGTCCCEVTGSAQNTGLGPEKTSFFQALGITTKISRGTIEILSDNPEVLDITEETLHSRFLEGVRNVASVCLMIGYPTVASVPHSTINGYKRVLALSVETGYTFPLAEKVKAFLAGPSAFVAAAPVAAATTAAPAAAAAPAKVEAKEESEELDEDMEFGLLD
The following text describes a protein:
Function:
Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MAKVTSSKLNIAIIHPDLGIGGAERLIVDAAVELASQGHKVHVFTAHHDKNRCFEETVAGTFPVTVYGSFLPRHIFYHFHALCAYLRCLFVAFCVLFMWHSFDVILADQVSVVIPILKIKRSTKVVFYCHFPDLLLAQHSTFIRRMYRKPIDYAEEITTGIADLILVNSKFTASTFANTFKYLDAKGIRPAVLYPAVNVDQFNEPSSFKLNFLSINRFERKKNIQLAISAFAMLNSPEGVLKHKDITNASLTIVESAQSCSLCVNYLVWLCGAIISQTGGFDKRLKENVEYLEELKDLAEKEGVSNNIKFITSCSTAERNELLSECLCVLYTPKDEHFGIVPLEAMAAYKPVIACNSGGPVESIKNGVTGFLCDPTPLEFSLAMAKLISDPQEADNMGREARRHVVESFSTKSFGQHLNRYLVDIHRGKED
The following text describes a protein:
Function:
As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is required in ciliogenesis and ciliary protein trafficking. Involved in cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body.
Sequence:
MRAVLTWRDKVEQCVYDLAFKPDGTQLIVAAGNRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTHNDSIQCVSYNPITHQLASCSSSDIGLWSPEQKSVSKHKSSSKITCCSWTNDGQYLALGMFNGVVSIRNKNGEEKVKIERPGGSLSPIWSISWNPSREERNDILAVADWGQKLSFYQLSGKQIGKDHSLNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRLGAVGEQTSWVWTCKVKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCKELVKKIAIYKNRLAIQLPEKILIYELYSEDSLDMRYRVKEKIARKFECNLLVVCADHIILCQERRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRNKLAVVDENDMCLVYDIHTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHQQKLQGFVVGYNGSKIFCLHVFSMSAVEVPQSAPMYQYLDRKMFREAYQIACLGVTDADWRELAMEALEGLEFETAKKAFTRVQDLRYLELINSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALDMYTELRMFEYAKDFLGSEDPKETKMLITKQADWARNINEPKAAVEMYISAGEHCKAIEISGEHGWVDMLIDIARKLDKAEREPLLMCAHFFKKLDNPGYAAETYLKIGDLKSLVQLHVETQRWDEVSPAIKRNLFAALREPTQSLKIKCFRFCAASAVQKQTVLSLNPAFALGEKHPEFKDDIYVPYAQWLAENDRFEEAQKAFHKAGRQGEAVRVLEQLTHNAVVESRFSDAAYYYWMLSMQCLDIAQDPAQKEVMLSKFHHFQHLAELYHGYHVIHRYVEEPFSFHLPETLFNISRFLLHSLTKDTPLGISKVNTLFTLAKQSKALGAYKLARHAYDKLQGLQIPARFQKSIELGSLTIRSKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFVFSASSYEVLHLVEFYLEEGITDEEAVSLIDLEAPRLKRENKWQEITSNNAQTLRLDESMDSVGDDDPFTAKLSFEQGGSEFVPVVVSRSVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPSCFQMFHSEDYELLLLQHTCCPYCRRRMDDPSP
The following text describes a protein:
Function:
Mediates the uptake of pyruvate into mitochondria.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MAASKIQALWNHPAGPKTIHFWAPTFKWGISIANVADFSKPPEKISYPQQVGVYILLSICGNKCLFNFSSIFFAKRDCHCLMLAAVTCTGLIWSRYSTVITPKNWNLFSVNVVMAGTGIYQLARKTRHDHFSEVQVPGKE
The following text describes a protein:
Function:
Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix, basement membrane.
Sequence:
MSSPNWSGHSALLLLLLLLLLNWASPSFISLNRGVRVMKGSSAFLLGDDLKFAIPKEKDACKVEVVMNEPMTQRVGKLTPQVFDCHFLPNEVKYIHNGCPILDEDTVKLRLYRFTETDTFTETFILRVYLLEPDCNIIRKSNNVLEVSEFYGLSGAIDKNLLRFDYERTAGLECTVRLDPVGSRLPAHGQVVLLEPRPEKPRGDQPHSFFPKSQLGTELRCPGGSCALGLKKMGSVNVSCEEFLLMGLHYQHTDPPSPNIDYISIQVDLTDGRSKIVYKSERAWLPVYIRPGIPNQIPRAAFMAMFTLEVDQFILTSLTTSVLDCEEDETPKSLLVFNITKAPLQGYVTHLWDHTRPVSSFTWKDLSDLQIAYQPPNSSHSVRRHYEVEVEVYDFFFERSAPITVHISIRTADTNAPRVSWNTGLSLLEGQSRAITWEQFQIVDNDDIHAVQLVTVGGLQHGQLTLRGGKGFLFTVADLQAGVVRYHHDDSDSTKDFVIFRIFDGHHSIRHKFPINILPKDDSPPFLISNVVIELEEGQTILIQSSMLRASDMDSSDDYIYFNITKPPQAGEIMKKPGPGLIGYPVPGFLQRDLFNGIIYYRHFGGEVFEDSFEFVLWDSHEPPNFSVPQVVTIHITPVDDQLPKEAPGVSRHLVVKETEVAYITKKHLHFIDTEYNRELLYTITTPPFFSFGHRHLDAGKLIMVDSISKLTKNSAARGLRSFTQHAVNHMKVAYKPPMQDMGLNPGYVQFAFSISNQHGGTLHGICFNITILPVDNQVPKVFTNPLRVAEGAQCVISTENVLISDVDTKLDSIYLSLQRLPQCGRVELDGFPLNIGDIFSWGDLHALKVRYQHDGSEILQDDIFLEVTDGTNSAEFILHIEVFPVNDELPILKTDLIPMMHCSEGEEVVITSEYIFATDVDSDDLKLMFVIAQKPQHGVVRKAGVTVDQFSQGDVISGAVTYKHTGGEIGLVPCFDTITLVVSDEEAGPFVNGCCYNGPHPSIPLHESFPVYALNITVHPVDNQSPSIAIGTMFVVDEGFSAAVTINHLSATDPDTATDDLEFVLVSPPQFGYLENTLPSAGFEKSNMGISIASFPWRDMKALHINYVQARHLRMEPTADQFMVYVTDGKQRSLEIPFYIIINPMNDEAPDFVVQNITVCEGQMKELESSTINAADLDVPKDPLLFSITHKPRHGLLINRVLSKDFPQNKQSVNPGQKHELVQNFSLELLKKGMKLMYVHDDSETLADDFTIQLSDGKHKILKTISVEITPVNDEKPMLSKKAEITMKMGETRIISSAVLSAIDKDSPREKIYYLFERLPQNGQLQLKTGRDWVPLYPGMKCTQEEVDLNLLRYTHTGAMDSQDQDSFTFYLWDGDNRSPAFDCHITIKDMGKGDIVILVKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQVQYVRYPGVPITSFSQMDIAGQTVCYVRKSKAAVSRDTFRFIVSNGLQTKRGVFEIILETMDRALPVVTRNRGLRLDEGTTGLLSPDILQLTDPDTPAENLTFMLAQLPQHGQLYLRGTVLLQHNFTQQDVDSRNVAYRHLGGDSQVDCFTFVATDSTNQGFVVDGRVGQEPVSFTIQVDQLDKTAPHITHLHSPSQVVLLKNGCYGIYLTSHVLKASDPDTNDDLIIFKILRGPQHGHLENTTTGEFIHEKFVQKDLNSKTILYVINPSLDVNSDIMEFQIMDPTGNSATPQILELKWSHIEWSQTEFEVCESVGMLPLEITRRGYSMDSAFVSVKVNQVSATVGKDFTLTPSKLIQFDPGMSTKMWNIAITYDGLEEDDEAFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSFNPNKHNAREKGIWHPLSPGSSSSTTSGSFHLERRPLPSSKRPAVTRGDTGQGFDSADPSRMKLRTQGNGKTVLPSSVYRNGTDIIYHYHGMVSQKLEGDSSPSRKRKAKVAITSLPQKTSQVAALPQADKMESTSDSHFSRQDRLPSIPKDCTLELKGLLHFHESLRKLYKCDGITWKAWSPQTEEVEGEACPAGWHHHSGYCHSLVTEQKGTWSTAARACKEHHRGSLVTVLSKQHMRWLWDISGRRPFWIGLNDQVHAGHWEWIGGEPVTFTNWRKGPPQRLKHGKDCVLAQRQGKWQVQDCRKGKPHNYVCSRKLQM
The following text describes a protein:
Function:
Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. Functions as a light-signaling switch that functions in root growth and development through the activation of Rop in a phytochrome-dependent manner. May act as a negative regulator of phytochrome-mediated primary root development.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing ROPGEF11 show retarded root elongation and irregular root hair formation.
Subcellular Localization:
Cytoplasm. Note=Interacts with PHYA and PHYB in the cytoplasm in darkness.
Domain:
The PRONE (plant-specific Rop nucleotide exchanger) domain is responsible for the GEF activity.
Sequence:
MVKAMEQEQETYKSRLFHFKNMNENSASRHVKSWSSDCAMRMDGSDNLDDDDNDMMMFRSQPGKCGSVDRPSLPIGGVTPNRNDKLPRVSSSDSMEALIILQAAMEQMKEKFSKLLLGEDMSGGGKGVSSALALSNAITNLAASAFGEQRRLEPMAVDRKTRWRREIGWLISVADYIVEFAPTQQTNKDGTSMEVMSTRQRTDLLCNIPALKKLDAMLLDCLDKFKDQDEFYYVKKDSPDSCETRNDEKWWLPAVKVPPNGLSEISRRFLQSQKECVNQVLKAAMAINAQVLSEMEIPESYLESLPKNGRASLGDVIYRMITVEMFDADQFLIEMDLSSEHKILDLKNRIEASIVIWKRKMVQKDTKSPWGSTVSIEKREQFEERAETILLLLKQGFPGISQSSLDISKIQFNRDVGLAILESYSRVLESLAHTVMSRIEDVLYADQLTQEPTNNAPSKNRYSLKENEKLREERLSFTEDMASGTLSDVMQWGNKNNEMKKESFFGDREKPLLSKVTGIMTNNKKSSYLDNLGAMRSPTARYS
The following text describes a protein:
Function:
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
Sequence:
MLSSRAEAAMTAADRAIQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPTFIKWLEEFTTQYTRDQKEPPQHQYLSLTLLHLLKDAHELFHVITSSLEDERDHQPRVTHLFDVHSLEQQPEITPRQITCRTRGSPHPMFNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTLNGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFSEFLMMDIYKYHLLGHKPGPRGEPCRKAGPALEVQDGPAAPKSVRSQPGGPKTQMLMNGACSPPFLPTLPAPVPFPLPAVPDHSSSAYLFQLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSKMQHQNREYKSEE
The following text describes a protein:
Function:
With S4 and S5 plays an important role in translational accuracy; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
Sequence:
MATINQLVRKPRAKQVVKSNVPALAACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGALDCAGVNDRKQARSKYGVKRPKS
The following text describes a protein:
Function:
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
Sequence:
MYYGFDIGGTKIALGVFDSTRRLQWEKRVPTPHTSYSAFLDAVCELVEEADQRFGVKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLVLNGKPITGQSYITGEFGHMRLPVDALTLMGFDFPLRRCGCGQMGCIENYLSGRGFAWLYQHYYDQSLQAPEIIALWEQGDEQAHAHVERYLDLLAVCLGNILTIVDPDLLVIGGGLSNFTAITTQLAERLPRHLLPVARAPRIERARHGDAGGMRGAAFLHLTD
The following text describes a protein:
Function:
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MGVNTKEFKIAICGDGGVGKTSLIHKLITQDFNAHYVPTQGADVKSIIVPTNQGYCIKFNCWDIAGVDKFGTLRDGFFIGSSGCIVLYDALSRSTHKSLPTWYRDFTRVCQGAPVVIACNKVEKSDDRKVGPKKIGRFLRQNSLPHSNMSVKTGYGIKLPFLHLARKLTGDDSLEFINSPALQPPPEVVEPDNDVENVALSSNQQMQRSRKLLIR
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MSIILPDWVAHHNDDKKGKLSTIFSVAVHPDSSRLATAGLDTKIRIWATATILNPRAENNSNSHRLLSTLSRHTGSVLVVRWANSGRFLASGSDDTVALIWDLDPSGMGGGSFGSSEVNIESWRPYRRLAGHESDVVDLAWADDDEFIATVGLDSKVIVWSGTHFDRLRIIDGHQGFVKGVVFDPLGQYLATASDDKTVKVWRTSDWGLERSITDPFLTSPSTAFFRRPSWSPDGSLLLCANAMSGPVFVASVVKRSSWSSDIYFVGHENAVVVTAFSPKIFVGFDGGTHSCVVALGSLDQSVSIWVTGLEQPVLVARDVFERQVMDLSWSADGYTLYACSSDGTVAVFHLSPELISDALSAEKLEQSRAKHGVKRVRNVAAATNGALPIGTSDRPNMLQPRKAGQSQAARASVPPVPIAGSVPPVRPIASRTERLHQTITITKDGKRRIRPTLIGDDLEPSQAVSHHHAYQPAPTSHALMPSIQQHQLPAMREAIGGTTVDGFGARPGVNGIHAGMTNSVSDGTAAAVVEAVLAAQRSNPAAMTTPMAAASSMMPYVPIGLPFGIMPEGASPEDMMQFWTEFQQRFMRGKKRKAEDAEAGSDSDDIEPIGKLQKGKTRADIGRTLGSEHPRDPPGPKKVLREALTGASGIVENGVRKGVHLAVPETLSIYRRDEDGLSIEIRNFDESRPTEIARLDPSDKDRVLWLDFSPTAATLATATSFFSAVALEDSTVLIYSSRGGRIGNLLLDSACYRLESNGVVLMAVTVAGLMYRWNIRADHEIHRPVSVLNLLGDPENLFSITVHANGAPIVILQSEKAYTFDDKKLGWVCISDGWWAEHSEAWDGRTRSRGSEVSVRDPVRAIEAEINTMYVRRVHGDNQVGAQEESDDDQTPPVEMSVPEDKKSDFVIAVTLRHLEARILAATILDSANEYKNHLIAYAKRIAEEGIKNQAEDLIKSLIGPIYYKPEKNQDAAWQPTILGFDKRQLCGQVLQILARPRNLTSLVQPYQEILANMKA
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
Sequence:
MSTPTHNLPRTRVSAFCWVALERSTRIERPTSWSWKELSHYSLIVFHCIPDTTPKQIEECFKKFLRRPDIVIILINQVYADMIRPTVDAHNLAVPTVLEIPSKQHPYDSSRDSILKRAQRVITPPERHY
The following text describes a protein:
Function:
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
Miscellaneous:
MISCELLANEOUS: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MPPSIPVPSIVTRAIPSLARAASTTTKSTPSKEHHVHSYSPEVLPLGYAVASTHASIKKKTGALDLGILVSTTDKPASAAACLTRNVFKAAPVTVTTQLLQSGGGRARGFIVNSGCANAVTGKKGLEDAWEMSNTVTSQLPPGQRGIGTLVMSTGVIGQPLPISSIISKIPELVRSLDDSPKSWLDLSKSFMTTDTFPKLRAKSFRLGERLVRIAGIDKGAGMIAPSMGPPQPPHATLLGVIATDAAISPPALQSALNYAVDRSFNNITVDGDMSTNDSIICLANGAAGKLETQGRETAESMEEITEDGHPEEYKVFREELRSFAEELAQLVVRDGEGATKFVTIRVKNAPSYETAQAVAKSIANSSLFKTAMYGEDANWGRILCAVGYTPTAQAIIPNHVSVSFIPSANVSDPTPLRLLTNGEPEANIDEDRASVILAEEDLEVEVDLGDGHEEAKVWTCDFSHEYVTINGSYRS
The following text describes a protein:
Function:
Required for myelination.
Subcellular Localization:
Cytoplasm.
Sequence:
MGNQMSVPQRVEDQENEPEAETYQDNASALNGVPVVVSTHTVQHLEEVDLGISVKTDNVATSSPETTEISAVADANGKNLGKEAKPEAPAAKSRFFLMLSRPVPGRTGDQAADSSLGSVKLDVSSNKAPANKDPSESWTLPVAAGPGQDTDKTPGHAPAQDKVLSAARDPTLLPPETGGAGGEAPSKPKDSSFFDKFFKLDKGQEKVPGDSQQEAKRAEHQDKVDEVPGLSGQSDDVPAGKDIVDGKEKEGQELGTADCSVPGDPEGLETAKDDSQAAAIAENNNSIMSFFKTLVSPNKAETKKDPEDTGAEKSPTTSADLKSDKANFTSQETQGAGKNSKGCNPSGHTQSVTTPEPAKEGTKEKSGPTSLPLGKLFWKKSVKEDSVPTGAEENVVCESPVEIIKSKEVESALQTVDLNEGDAAPEPTEAKLKREESKPRTSLMAFLRQMSVKGDGGITHSEEINGKDSSCQTSDSTEKTITPPEPEPTGAPQKGKEGSSKDKKSAAEMNKQKSNKQEAKEPAQCTEQATVDTNSLQNGDKLQKRPEKRQQSLGGFFKGLGPKRMLDAQVQTDPVSIGPVGKSK
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTPVSLSQVEKKTIESILTNKKEEGKLITKVTILNEKKKKLEIKTLILSSNRIFLFTDSKGKLSAEHHYLEITEIASQSENDVTIKFKNQNVMKMNLDASEVLKTLYGTLMSTFPGIKIGKTIIFNITPASRIPSIFQATSFKDIQGCGSFNLTYRSVCDHLGVQPLSSILWDIENLYPFNQVREFNLAEIYQYSFTDLKAILLSLSYNTYFQSFQSNGKLSNEDLNLLAEVFKENSSLQQLTITNSQASKEPIITLLQNVAENKALHLSHINLNNNSLENKGILTLGSSIQTFSNGLTYLNIENTSCSGKGLEAMFGCLTANNVVCGSMTHLNISNNKLESYGTNGLCKFLSKATALQQLLMSNTSPVYSFLKTSSSSIQTLDFSGNKSTTTKESVIDILSFFKQMSHLQTVNLSRIQTTPDDLKLLFSPATSLLKCSSVDLSENDLGDGGIIKLCEIMYPNSNLHHLSIDGNFKTKSKLRARAIEALINLIDDNTSIESLSLASGSGKYQLKGDLMPLLLSLLKNQSLVKLDISGNGVGDSGALAVSKILWKNQTLKSLKCDGNDFSYTALKMIKCSIRRNEKSLTILQLPLSDISTILKNDSNGSSHEKILKTIQDIQTSIVINYPNNIHPIDTSSGGLTPTKQPSIGSLAGVIKKPPIGPPSTPTKSSNPGFQTLPKRPTRGPLYPGRATGGAVTLTDKAQINASTIELPPLVSRSIDLLMEQGISSVGIFRTCASATALKKIKTRFEAGEDIDLKAENVDVDTVAGVLKSYFRELPNPIFPENLHEYFFQAMRQSSNEEIIQSLKDIIDQLSPLECKMIKKLFHLLHLISLEKDVNMMSPENIAICWAPTFFRSFASELLPINSFMIVNYFDIFDPENKPISSDNSGDADTDSTQSTCTTNNNNLVATSLSSPISPSTTPTKSIDNVLHTTVEVSRSPNHERAHTVGPMTSKRPISNNNGVSSNTPPLPNNVTPHHNTMPSRPSASPIKRPPSMGGSLSNFAGIPLSNHSSSGQLNNNNSNNNTTSNSSNSSSGKSSSNPSPIPTPPDSPSMSYIGDGKSTLRSKRFSRVNRVSYSPVLPRAWTNESRTVSSLFQDDLDSNSDSSGPSL
The following text describes a protein:
Function:
Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MDEEDLTDIPFADLQKLRDQVGIKRYNQAIRNTEGKKGNKLTDNNTKYRPQEFSSKKPVSVLRQIHQTKKSKPKDPRFTRKSGTLNEDLFEKSFGFIKELKTNEEQMLIKQLHKTKDKSRKAEISAALERLNQQQQHITERKQKQEIIKQHRKKEIELIEKGKKPFYLKRSMKKQMFVEQKHDTLKKQRKLDKYLKRKTRRDTAKERAKMPKSRQVTE
The following text describes a protein:
Function:
Nuclear serine protease which mediates apoptosis.
Sequence:
MVGTNGVATRAKRKSHPTVPERPQKQLRALNGKESTGVNTPELDLISDDDYDLDGPQLVPGLAADTAEWQAAIEQVVRNVVSIRFCQTCSFDTDPALTSEATGFVVDAERGYILTNRHVVGSGPFWGYCVFDNHEEVDAYPVYRDPVHDFGILRFDPKAIKYMPVTALGLRPDLAKVGSEIRVVGNDAGEKLSILSGVISRLDRNAPEYGDGYCDFNTNYIQAAAAASGGSSGSPVVNIDGYAVALQAGGRSDGAATDYFLPLDRPLRALQCIQQGKPITRGTIQCQWLIKPFDECRRLGLTPDWEDVVRTGFPKETGMLVAEIVLPEGPSHKLIEEGDLLLKVNGELLTQFIRLDDILDSSVGQTVSFLIQRGGEDIEVAVDVGDLHSITPDRFVSVAGGSFHDLSYQQARLYGVACKGVFMCEASGSFRFEGTDNGWIIQTIDHKKTPDLESFIEVMKRIPDRERVVVTYKHLRDLHTLNTGILQVDRHWSSKMRLAVRNDISGLWDFTDLADALPPTPPVARSAKFIQLENSQHPAAADIVRSFVRVLCHMPVKLDGYPRNRKWELNILCSFYTNMRLVAAKTTITEITAVAIPAKAASPRYRAINIDAITVDTSLSGQCGSGVLIGEDGIVQALWLTYLGERSQSSSKDVEYYLGLATPTLLPVIKKIQNDEKPKLRMLSVEFNTIQMAQARVMGVSEEWIHKVAEDNLSRHQLFMVRKRTFERNSESGALLEGDIILSLNGKIITRVNELDVMYDHEVLDAVIVRDCKEMSIKLDTVSADDLETDRAISFCGAILHRPHHARIAIIPIQPCTHQLCDTCQWETNTGFRIVLEGDFRIKVVTFDNVPWVITMKKNDHYFPTTEWIKDPTEKSGWKRITYEMGNAVEGEGKEGIRSVIGDDVGDFGDAGGADEPMSFRSLF
The following text describes a protein:
Function:
Involved in the mkh1 signal transduction pathway that plays a role in cell wall integrity. Activates spm1/pmk1 via phosphorylation.
Sequence:
MSKKPVLNLDTSNGFSEEYISHPERNDNQGIVEITDLVFSSESKLTQRKESRDSKTFVPSFLEELDDDHLHELVTNGGILYMNSLGEGVSGSVRKCRIRGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCTSPYIVKYYGACYNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLSGLSYLHDRKIIHRDIKPSNILLTSKGQVKLCDFGVSGELVNSLAGTFTGTSYYMAPERISGGSYTISSDIWSLGLTLMEVALNRFPFPPEGSPPPMPIELLSYIINMPPPLLPQEPGIKWSKSFQHFLCVCLDKDKTRRPGPQKMLTHPWVKAFERIHVDMEEFLRQVWSD