lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of NRD1 and NAB3 with RNA polymerase II. Also has a role in transcription-coupled histone modification. Required for activation of RAD6 ubiquitin conjugate and the BRE1 ubiquitin ligase which ubiquitinate 'Lys-126' histone H2B. Activates the SET1 histone methyltransferase complex for methylation of 'Lys-4' of histone H3 and for methylation of 'Lys-73' of histone H3 by DOT1 and 'Lys-36' of histone H3 by SET2.
Miscellaneous:
MISCELLANEOUS: Present with 1110 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleoplasm.
Sequence:
MSSESPQDQPQKEQISNNVGVTTNSTSNEETSRSQDDNVKEVNGNDDTKEEEQEEDAELDDLFGDDNDDDDDDDVKKSETEKSDSDSDEDDEGENINHRSRHRESLGLDDDEAEEQAMYTRKFYGEDANNFSDQDETTHTFKEENVELVRHIIPSKANVNETASHNEIFYARIPNFLTIDPIPFDPPSFEAKVNERASNSASREDQLDDRLIDENTVRWRYSRDKDQHVFKESNTQIVQWSDGTYSLKVGEECTDILVNDTSNTFLTVSHDQQELIQCYEGGEIKKTLMFIPTSTNSKIHQKLSKAVIRRNQRQSKGPGTYIVSMDPEVEKKELERKQSQILRDRRRRQLKEKEKQESPDAAFETGFRKQNSPTTYGASRRNEYEEDDFLVDDDEEEEAAFDDEEDDNEEEEEEEDADEENASRLRNLKREGAAMYREEEEEEKDRSETKRRRVAVIEDDEDED
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MKLLKPPWVNHDGKPIFGIDIHPDGTRFATGGQGDDSGRVIIWNMAPVINEKDEQDENVPKLLCQMDNHLACVNCVRWSNNGHYLASGGDDRLLMIWKMMGTGTSAVFGSSVSNVEQWKCSHVLRHHTGDVLDVAWSPSDLWLASCSIDNTVIIWNAVKFPEMITVLKGHSGLVKGVSWDPIGKYVASQSDDKSVRIWRTSDWKEETAVFKPFTECGGTTHVLRLCWSPDGFYLVSAHAMNNRGPTAQIIEREGWEPTMDFVGHRKAVTCVRFHNSIFTKPSKKSTIKAHNYSICAIGSRDRAISIWMTSLKRPLVVIHDLFSNSVMDVSWSLSGGDLLACSWDGTVSYCQFDMEEIGRQLTLEERNKIHEGLYGKRVLSKSLASNTIIENPAMLQLMQQQQKQKEEEQETAKQMVVSAPTKRNLPANSVMEGQPIDVKRRQIETRTKDGRRRITPIFIAPQQCPVGPPAPFTVTSNSAFTVTVSGTKDESSTAFKENSDKTQTIKQEALEKDQEQMESTGTDKKAPSALDSRFTERAKTPATTPTTARTDVSSSFSKEMQFTTPVTVHVPRRKEAEPTPAQGLIPSTAASTAAPASAPPVVKRSRGRPPGSGRAAVLAAAAASAAAAAAAARATPPGPQGAPERDTSRLTGRRSLQLPTPSANKTISTQVIGKQAAGEGKVTIEVDNEVTAGRLTIQKLRCIKSGQTVWETILTCKALSLVANSNFICVNCEDKTLGVYSPSGRRLLPSLVLPSVGSSIKIKGYHIMAISTCGKLFVWDVRKQQAVVNKVSLETIIEPGISISKSLLTDQGVPVIGLSNGKSFMYSNPMCCWLLIDHKEDILRLTSDHQPCQPAQTPSHSGGPLSHVQGAQQRLSSQTRSMFPGNHNLQQAATLTHLENQVSAALALQSAKEYRFWVLTYARYLVQEEGEGRLRELCNDLLGPFYQGDQEEGGWQSSILGISKRGLLRDILPILGSNLKLQRLYSEYEDQLEMAPR
The following text describes a protein:
Function:
Required for CNS development: midline glial cells. Involved in the metabolism of insect hormones: responsible for ecdysteroid C2-hydroxylase activity. May be involved in the breakdown of synthetic insecticides.
Miscellaneous:
MISCELLANEOUS: Member of the Halloween gene group.
Subcellular Localization:
Mitochondrion membrane.
Sequence:
MTEKRERPGPLRWLRHLLDQLLVRILSLSLFRSRCDPPPLQRFPATELPPAVAAKYVPIPRVKGLPVVGTLVDLIAAGGATHLHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQYPQHPLPDAWTLYNQQHACQRGLFFMEGAEWLHNRRILNRLLLNGNLNWMDVHIESCTRRMVDQWKRRTAEAAAIPLAESGEIRSYELPLLEQQLYRWSIEVLCCIMFGTSVLTCPKIQSSLDYFTQIVHKVFEHSSRLMTFPPRLAQILRLPIWRDFEANVDEVLREGAAIIDHCIRVQEDQRRPHDEALYHRLQAADVPGDMIKRIFVDLVIAAGDTTAFSSQWALFALSKEPRLQQRLAKERATNDSRLMHGLIKESLRLYPVAPFIGRYLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQPERVLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRVALKQLHSLLGRCAAQFEMSCLNEMPVDSVLRMVTVPDRTLRLALRPRTE
The following text describes a protein:
Function:
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
Subcellular Localization:
Cytoplasm.
Sequence:
MSLRLRGHAASRGNALGRARVRQSHTLEVAEQRVPANQVETQLQRLHAAIAAARTEMQQLRDRLHGALAREVGEFLELHALLLDDPELLQGLDDLIRTHRYSADYALRVQRDRLAAVFDGMEDAYLRSRMDDLDHVIGRIHAFLHKRAPDLKGVAGEILVCDNVAPSELAQLQAQGVVGIVTTAGSALSHSAILARSLHLPLVVGVADAVQRVNDGDVLIVDAGSGQVIVDPTPEHLRDYRERLRTLAKEQRELGRLRSKPTRTRDNVDITLLANAESLEDVAKAHALGASGLGLYRTEFLFLQRNELPDEDEQFHTYRDTVLGMSGRPVTIRTLDLGADKADRTGLTLSDEDNPALGLRGVRLSLARPAVAQAQLRAILRASGYGPVRILVPMVSGREEILLVRKQLKKLTAQLRDEGHEIAEHIPLGAMIEVPAAALALDCFIDDIDFLSIGTNDLVQYLLAVDRNNEALGELYSPLHPAVLRLIAQVIATGRAHNKPVAVCGEIAGDPRFVAMLLALGLTEFSLHPATLLEVRRAVRDLHLGQLRVHGEKLLRARDRKSIEKWLASVAQGLLH
The following text describes a protein:
Function:
Multidrug efflux pump.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTKRYPMKEILDTSIPIIAEMTLYNLMIVFDMMMIGNYGGNKCLTAVGLSNGVIFTLCDVFISVGLAVSVTSLIARSIGSRHYKNAQQYSICGLFLGVIISFLISYFMFYKSEKILYIAGARGDILKIANVFNKTMAISIFFKMNTEIINSILRGYKNTKIPFFTAVIISSCKIILDFIFIFGIGKNGLGVFGAALASILSQIVGFTFSFIYMLDKLKSHGNINLFKLFKIDKIKDILNMYIPASLEEATYSVSRLLCAFMIIKIGSISFSANEIANTIETVSIIPSAALGVSATTLVGMKIGEKDYRGAKEYANKSVWFAVSISLIFSLLFIFMPNLLVGCFVGNKEKNVVKLATVCLLVGAIEQPFIAASTVVEDILKGMGDAKTPFIVTLISSWCIRVPLFYYYIYKLKYSVVCVWWITAFQWFIDFLLMKIILKKKFNKFKL
The following text describes a protein:
Function:
Displays both glutathione S-transferase and glutathione peroxidase activities toward oxyeicosanoids. Catalyzes the Michael addition reaction of reduced glutathione (GSH) to electrophilic eicosanoids to form GSH adducts, as part of detoxification or metabolic shunt processes. Mediates GSH conjugation to leukotriene A4 to form the sulfidopeptide leukotriene C4. Metabolizes cyclopentenone prostanoids, specifically mediates GSH addition at C9 within the cyclopentenone ring of 15-deoxy-Delta12,14-prostaglandin J2 (15dPGJ2) to form 15dPGJ2-glutathione. L-cysteine cannot substitute for GSH. Catalyzes the reduction of eicosanoid peroxides to yield eicosanoid hydroxides.
Subcellular Localization:
Mitochondrion outer membrane; Multi-pass membrane protein.
Sequence:
MAVLSKEYGFVILTGAASFLMVTHLAINVSKARKKYKVEYPTMYSTDPENGHIFNCIQRAHQNTLEVYPPFLFFLAVGGVYHPRIVSGLGLAWIVGRVLYAYGYYTGEPRKRQRGALSFIALIGLMGTTVCSAFQHLGWVRTGLNSGCKSCH
The following text describes a protein:
Function:
Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity.
Miscellaneous:
MISCELLANEOUS: Complements holdfast synthesis in the C.crescentus mutant lacking hfsE, pssY and pssZ genes. Can also partially complement the O-antigen defect in the S.typhimurium wbaP deletion strain.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTNLKKRERAKTNASLISMVQRFSDITIMFAGLWLVCEVSGLSFLYMHLLVALITLVVFQMLGGITDFYRSWRGVRAATEFALLLQNWTLSVIFSAGLVAFNNDFDTQLKIWLAWYALTSIGLVVCRSCIRIGAGWLRNHGYNKRMVAVAGDLAAGQMLMESFRNQPWLGFEVVGVYHDPKPGGVSNDWAGNLQQLVEDAKAGKIHNVYIAMQMCDGARVKKLVHQLADTTCSVLLIPDVFTFNILHSRLEEMNGVPVVPLYDTPLSGVNRLLKRAEDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYRQLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIVFLTVFKGFVNKAAY
The following text describes a protein:
Function:
Involved primarily in the early steps of meiotic recombination. Required to ensure reductional chromosome segregation.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to meiotic chromosomal axis sites.
Sequence:
MFYNQDVLTKEKGGMGVIWLAATLGSKHSLRKLHKKDIMSVDIDEACDFVAFSPEPLALRLSSNLMIGVTRVWAHQYSFFHSQVSTLHLRVRKELDHFTSKPFKNIDIQNEQTNPKQLLLAEDPAFIPEVSLYDAFNLPSVDLHVDMSSFTQPKENPNISVLETLPDSTSYLINTSQNYSLRNNVSSFVYEDSRAFSTEEPLDFEFDENGDIQELTKGTINSDPSLQAASQHSNLGSVQREYNSEEQESRIHMFEIDEDVLPLPVPLQSVMDSEHNENEPRALKRRKVQKLLEPDENIELSTRTLSQWRKNYVERMIALEATKYVRRRGASSAKKKELNKFFDWESFHPLLKPWIEKLKPSNNTPSEIDDVLRNIDTSEVEVGRDVQGELGLNIPWNTSSRSNSAINSKSHSQTGSEHSTPLLDTKYRKRLPHSPSMPSRVEFLPALESSQFHETLNSELSLQLSDDFVLYKNTQEENAHLMLSMEKECANFYEYAKTAIYENNGRITFSSLLPNDLKRPVVAQAFSHLLSLATKSAFLVKQDKPYSEISVSLNLKSTDAI
The following text describes a protein:
Function:
Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MSGLPAPVRVSPLIKFSRWSLLTVGVLYGAFHQNRLSKKEAAFREVELKQKAIRDEKLAAEKKLAADKEIAELEALAK
The following text describes a protein:
Function:
Responsible for a rapidly fatal enterotoxemia.
Sequence:
MKKNLVKSLAIASAVISIYSIVNIVSPTNVIAKEISNTVSNEMSKKASYDNVDTLIEKGRYNTKYNYLKRMEKYYPNAMAYFDKVTINPQGNDFYINNPKVELDGEPSMNYLEDVYVGKALLTNDTQQEQKLKSQSFTCKNTDTVTATTTHTVGTSIQATAKFTVPFNETGVSLTTSYSFANTNTNTNSKEITHNVPSQDILVPANTTVEVIAYLKKVNVKGNVKLVGQVSGSEWGEIPSYLAFPRDGYKFSLSDTVNKSDLNEDGTININGKGNYSAVMGDELIVKVRNLNTNNVQEYVIPVDKKEKSNDSNIVKYRSLYIKAPGIK
The following text describes a protein:
Function:
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
Subcellular Localization:
Cytoplasm.
Sequence:
MIWYPFTLQFEPDSPLKIERAKGEFLYDELGNSYIDGISSWWVSIHGHNHPKIVQAVKNQLEKLDHVLLAGFTHDPAEKLAAELLKITDGLFQKVLYSDNGSTAVEIMIKLAYQYFQNIGEVDRKIFIKWNSSYHGDTIGTMSVGGNSVFNRVFQGLMFPTKEFQTPNCNFCPMGKKPESCKVECIDPIEKFFQKSPKAVAGIVIEPLILGSGGMIFYKEEVLQRLETISKKYGSLLLLDEVFTGFGRTGSVFAYQRAKIRPDFIALAKGLSAGVSAVAVTLTTDRIHSAFVTADPEKGFYHGHTMTGNPIACSAALASLKIFFEENRLEQILRLESKLNVGLKKIAKEFPKAVKNCRVLGAVGVLELEVGKASGYHYPGNKILKKKFLEKGVLLRPLGNVIYLTPPYNIENSSLEKIFSAIRETLSEISFGN
The following text describes a protein:
Function:
Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.
Sequence:
MPRPPEDPDVRNSKTLAYILRHGAEKEGLYIRSDGFIKLADVLARPKLKGVDEPTILHLVQTNAKKRFELFWGYDPSPPRPKKKPTQGKTKKQLQRDRETAAAAAASAAVAASGTGEGQEKGKEPDAATIDIIASSLASTDLTAPPSSLSINSTAPAPAQSSTSVDPPELPLISLPDPHTSASDSDANASANSDNPKGEYFIRATQGHSIQLESTAHLEQVKDDEEGKRKVGLMVHGTRWELWDTLKEQGLQKMTRQHIHLAPGFSGPITPRPNSTLYIYLDLSKLVAAGIPVYVSANGVVLTPGSKGGENGEGAGVGKEFWRRAVRRKEGKRWVVWEDGREVEREELSGEE
The following text describes a protein:
Function:
Role in flagellar biosynthesis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Sequence:
MTPEIFVELFKESLWLVLIMVCAIIIPSLLVGLVVAIFQAATSINEQTLSFLPRLIITLLALMFFGHWMTQILMDFFYSMIERMPQVLY
The following text describes a protein:
Function:
Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host. Acts as a TF receptor and is required for TF utilization. Involved in the initial capture of TF. Helps select only those TF molecules that can be used as an iron source and concentrates them on the cell surface, maintaining the iron-loaded status of the TF C-terminal lobe until its delivery to TbpA.
Miscellaneous:
MISCELLANEOUS: N.meningitidis cells will only bind to human TF, not bovine or porcine TF, explaining at least in part the bacteria's inability to cause infection in non-human hosts.
Subcellular Localization:
Cell outer membrane; Lipid-anchor. Cell surface. Note=Requires Slam1 for surface expression in E.coli.
Domain:
Has 2 lobes, each of which has an 8-strand beta barrel flanked on their N-terminus by a 4-strand handle domain. Electron microscopy suggests that in the TbpA-TbpB-TF complex, TF is captured directly above the loop domain of TbpA in a chamber of about 1000 Angstroms(3) formed by the 3 proteins, where interactions between the proteins serve to abstract iron 2 from TF.
Sequence:
MNNPLVNQAAMVLPVFLLSACLGGGGSFDLDSVDTEAPRPAPKYQDVFSEKPQAQKDQGGYGFAMRLKRRNWYPQAKEDEVKLDESDWEATGLPDEPKELPKRQKSVIEKVETDSDNNIYSSPYLKPSNHQNGNTGNGINQPKNQAKDYENFKYVYSGWFYKHAKREFNLKVEPKSAKNGDDGYIFYHGKEPSRQLPASGKITYKGVWHFATDTKKGQKFREIIQPSKSQGDRYSGFSGDDGEEYSNKNKSTLTDGQEGYGFTSNLEVDFHNKKLTGKLIRNNANTDNNQATTTQYYSLEAQVTGNRFNGKATATDKPQQNSETKEHPFVSDSSSLSGGFFGPQGEELGFRFLSDDQKVAVVGSAKTKDKPANGNTAAASGGTDAAASNGAAGTSSENGKLTTVLDAVELKLGDKEVQKLDNFSNAAQLVVDGIMIPLLPEASESGNNQANQGTNGGTAFTRKFDHTPESDKKDAQAGTQTNGAQTASNTAGDTNGKTKTYEVEVCCSNLNYLKYGMLTRKNSKSAMQAGESSSQADAKTEQVEQSMFLQGERTDEKEIPSEQNIVYRGSWYGYIANDKSTSWSGNASNATSGNRAEFTVNFADKKITGTLTADNRQEATFTIDGNIKDNGFEGTAKTAESGFDLDQSNTTRTPKAYITDAKVQGGFYGPKAEELGGWFAYPGDKQTKNATNASGNSSATVVFGAKRQQPVR
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.
Subcellular Localization:
Membrane; Single-pass membrane protein. Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MAGAPHPHTYMGWWGSLGSPKQKYITQYTISPYAAKPLKGAAYNAVFNTFRRTKNQFLYVAIPFVVVWSIWTRARDYNEYLYTKEGREELERVNV
The following text describes a protein:
Function:
Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
Subcellular Localization:
Cytoplasm.
Sequence:
MYPSTLPAEADPSTMNGSSVAEPPDFQAATAAAAAAARASSLEQDEWSVGECGFLDPDVQRTMRSGSAAEDITQYPMHGWVDVTKEFHDACAELQPGELAQDMLFGLFEAMSAIEIMDPKMDVGMGFDKQDLPPPSFEAAIATGAIKLDDLTPSELIGIYDALFSCLVSWLEGNSMDQVLFTCLYLHAPAQIKDKALRVFCTAVRNLIVVIKKIIAVAAVNEEEDFQLYGNSALLAAEKAQPATVYSSLKDVEDELIRKCKKLTSTEDWMAVVHRLRFMRHLFQVIYHVEQMASNDTVDDKVDIYKILLVASEMLPGIRNTLDRGTQPEKGSDAPNPMGFSPRIHDRSQPPAFPRSIKIRDRPSSYQFLEEMISRFKYACKVTKYKDYYSALNFFIEYSKKSGQCILSRSVLQTLFSANMRMAHGKLPMKQFLRHSVQVFNSPPVLNAKHPVAADPKVQQHLENFFRYCINMNTFTQFIRICGFNRARQRDKLARLIENFDTIQVDAARLDSMMNQLANERAMEGNEPMATALKHSTHFSTWVLYNCFRAMLIFLMSGFELELYAVHEFLYIYWYPYEFLIGFLVSALTRTENILLAQEEYAEHQSKTQSGGSGAAKNRKAAKPKKNKKTQRPYRAEIVFYHALLSLCGGMYKAMGALTKDGRVRLPLSKFDNEEIRYNRRFLPFATLTSPPPVSYAEFKNVREHMMRHSVEDLYTYAAKHFDQARNVLESIQNPDQEMLDLLQIARTNFVVMNVLARGHQKEVKRQPEFDFSKHSYFPIIKLK
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSDAEGQGFVHLRVRSAYSLLEGAIKADQIGKLAAEAKMPAAGLADRANLFGALEYSSYAKDAGVQPIIGCAIPVVGIGGGPTERWARAPTLMLLAQNERGYLNLSELSSIAYLDSAELPEPVVPWAKVAEHSEGLILLSGGTDGPVDALFAAGKTAEASAALAEMHRVFGDRFYVELQRHGLPRQAAAEPGLVNWAYDHDVPLVATNDVYFAKPGFYDAHDALLCISDGAFVGQDERRRVTPEHWFKPAEEMRKLFADLPEACDNTLDIARRCAFMVHKRDPILPSFPTGDGRNEAEELEHQAREGLKMRLEGLTLSAPEEEYWKRLDFELGIIKKMGFPGYFLIVSDFIKWGKAHGIPVGPGRGSGAGSLVAWVLTITDLDPLRFGLLFERFLNPERVSMPDFDVDFCQERREEVISYVQEKYGRDRVAQIITFGSLQARAVLRDVGRVMQLPLGLVDRLCKMVPNNPAAPVTLAQAIDLEPRLKQAKKEDANVSACLDVALQLEGLFRNASTHAAGLVIGDRPLTQLTPLYKDPRSDLPATQFNMKWVESAGLVKFDFLGLKTLTVLDRAVKHLKKRGFEIDLGKLPFDDAKTYELLASGQTVGVFQLESQGMRDTLRKMRCGSIEEITALISLYRPGPMDNIDTFVDCKFGRKPVDTLHPSLEAVLKETYGVIVYQEQVMQIAQILAGYSLGEADLLRRAMGKKKKEEMDLQKIRFVSGAKEKNVPEEQSGSIFELVAKFAGYGFNKSHAAAYAFISYQTAWLKANTPVEFFAASMSLDLSNTDKLAVFHQDARRFGITVRAPDVNRSGADFEVENGEVLYALGAIRNVGLEAMKHLVAVRAEGGPFRDVFDFVERIDPRQVNKRAIENLARAGAFDSIHKNRAQIVASADVLIAHAQSCHADRQGGQGGLFGSDPGAGRPRLSKTENWNQVDLLDEELSAVGFYLTGHPLEDMVGMLRRRRTVMLAEAMAQAEAGAEAFRMCGVVRRRQERASQSGEKFAFVSLSDPTGEYEVLYPPESLRKCRDVLEPGKAVAIKVRAKARDGEVRFFGDDAEPIEKAVENVVAGLRVHLSPSAAEIDALKRRLEPAQAQKGGEVTFVAAIGGGREIELRLPGRYTLDAALRGALKTAPGVALLEDV
The following text describes a protein:
Function:
Reversible blocker of both Kv1.3/KCNA3 potassium channels (high affinity) and Shaker B (mammalian Kv1.1 analog) potassium channels (very low affinity).
Subcellular Localization:
Secreted.
Domain:
Has the structural arrangement of an alpha-helix connected to a beta-sheet by disulfide bonds (CSalpha/beta).
Sequence:
MRFTGIILILISMTLIDSFFEMKVEATGPQTTCQAAMCEAGCKGLGKSMESCQGDTCKCKA
The following text describes a protein:
Function:
Component of the chromatin assembly factor complex (CAF-1) involved in chromatin assembly following DNA replication and DNA repair. Required for several aspects of development, including apical meristem maintenance by regulating the durations of the S- and G2-phases of the cell cycle through its chromatin assembly activity.
Subcellular Localization:
Nucleus.
Sequence:
MEGGKLLGVAHPEPANNIDADLRYDLGQSRMQVDGPVVLNRSAELEPSDSMAIDDVPVEASSQPAPAKQSPALMDTIVEVQKQLKRKRASSGPALAAADKDALVAGCCQELEGLLEYYREVSGHRMQFEVGNLSTNAAIGCLLEESSLGLSKLVDEIYEKLKGMEGVSATSVRSSVLLIGQRMMYGQSSPDADVLEDESETALWCWEVRDLKVIPLRMRGPLSTRRTARKKIHERITAIYSTLSVLEAPGAEAQVNDMRKASLKLSKALNLEGIKSLVERATQKSNIERGAKNTGSTAKEPMQEMVKSNNDTGIIENVDDSQLQKNTSTNEKDTQKAQKQVEKELKQKEKEEARMRKQQKKQQEEALREQKRREKEEAEMKKQQRKQEEEAQKEQKRREKEEAETRKQQKKQQEEAEKEQKRREKEAVQLKKQLAIQKQASMMERFFKNKKDSEKLEKPGGKDSGVQTTDPCTTNKEVVPLVTSIIDSSFSQKENWALEDLRRLQISGWQKLSSYNRSSRWGIRNKPKKEAFKELKLQKTSDNMLEEILSPNEDTCHNLSQENEPDKSANDVDMLPAVELQFHGTNHANPLPTRSIKRKLLQFDKSNRPAYYGTWRKKSAVVGPRCPLKMDPDLDYEVDSDDEWEEEDPGESLSDCEKDNDEVMEEDSKITDEESEDSFFVPDGYLSDNEGIQIESLLDDKDEASSSPPDQCAEVEEFRALLRQQKVLNTLTEQALRKSQPLVISNLTHEKAELLTAGDLKGTSKIEQLCLQVLSMRICPGGATIDLPVIDSSSANAEETNQLNVKSSPAAASAIPDTDLAEIVKVIGSCRDGINKLVESLHQKFPNVSKSQLKNKVREISEFVDNRWQVKKEVLSKLGLSSSPASSKKPKSIATYFSKRCLPPEEAILASPELRLKSKTTQNVNGDTDIPRINLLPSSQ
The following text describes a protein:
Function:
Required for normal Golgi function.
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MDSDYIFHNGDDIRNMGLEEMRRQKVLLASELKAIDAQISDLAFNNYGTYADAGRATHDCSKTFGEMRDKTVNLSDQAEELTSAFVEFRAKAKQLSEEQDLVRKALDKSNPIWELLTLPSRMDICIRAGYYDLAYTLTNYGLQLQQQTQLYRNPLIKKVADHLVEARAYLLEELFNKFAGPLDLAESIKVVNNVRKMPSLTANQLRIAVLQHRDIYLEKQILDISGNVDMIVQAIEIYRTSMYDTLVLYLAVFPENEVVRKNPNADPRWESWPVLPPNSILSQWVISNVKKMLDLITKADVKSAVDLSAVWTKLMAMASSFGRMGIDFRPLIAGKLTKLIEQRFRQNVQEATSRLTGSSRDIVMIGIDPASLPQFETAPDSPPVAAAELSLWDDMTIYTNSVVDALNGLRFILTPVVLSTVVVSLRDSIRSILTWLASSHSNSANFSRAVRIVCTSVAPFFEKCVAFFFPPATVSKIFGSSISKRQYLQFIELDMKQLAASCDGAEKIEEIVKPLLQKRTLEEIGLENVLKPTKPEEEKTKFFLEETVEDGPGLAEPQEEASESVKEQETTSELEKKHGTDFETAETQEMVSEPVKEHETTSELTKEQEPAFEPEKLHETPPEPMEPQNFGESEAKAAHNPEAHLELGETSENQEIREQEHKEVVITSTEPEFHEIDLNSAVLIPKIAVEPQLDPISEYLTELTQDDPIEEEEGWGWGDDDGEEQEISSKEVESPKEKCKKDD
The following text describes a protein:
Function:
Transcription activator that binds DNA in a sequence-specific manner, likely 5'-GAAATTTTGG-3', to promote the expression of target genes (By similarity). Required for pathogen resistance.
Subcellular Localization:
Nucleus.
Sequence:
MMLPTKRPAPDHGDDERNEVMVPEPKRRTNLKKNIMGVGGLSFNKIVLNLEPMLRIWVHEAVEAAIRSSIHPSSRPSLNRIEASRGRRLQLRFVDKPPSTIFTGSKVEAENGNPIRIILVDATSQAMVSSGSLSSIKVEIVVLNGEFGTDERQDWTENEFNASVLREREGRRPLVTGDLNITLVDGVGTVDNVIFTDNSSWIRCRKFRLGARIVQRSAGEVTIREATSDAFMVKDHRGELYKKHYPPLLHDEVWRLERIAKDGAFHKRLAYKNVHTVKDFLRLLVTDPIALRNILGGGISNRVWETIIEHALSCVPDDDEWYTYHGTAQRVELLLNSIYNVVKVTFDGQDYLPVENLTFSQKLLVEDAKRQAYKNVWNLTPFDRRAIMGPSMPFTDLLPEPVGTSNLLLQQHDFSGTRPDMPLGLNQSSTSFSYEVENPKPLQGIEPLNPMLRNSSFRMEGIFPYNADNSFSFFADDGFGTNQDNTQAQMLSLTSATPAWAQGSGFIFTPDYETSSISFLSSFPSCNVNDRSIGETREVCPKNRWLKVRAVIQWKSISRGAAKRRRQHWLQHGICT
The following text describes a protein:
Function:
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
Subcellular Localization:
Cytoplasm.
Domain:
The beta-hairpin motif is involved in DNA binding.
Sequence:
MRRTGGRGAQAGVTRLHPPFRLPSSLRCGRKLLADVQTLFEPLPCVCLAHRCRRTLEVVMLKVRSEFKPSGDQPTAIASLVDGLESGLRYQTLLGATGTGKTYSMAKVIEEVQRPALIMAPNKILTAQLASEFREFFPDAAVEFFISYYDYYQPEAYVPGKDLFIEKDASVNQEIERLRHSTTRSLLTRRDTIVVASVSCIYGLGDPKEYTALNAIVKKGGVMPRDELLGRLVNMQYERNDIELMPGRFSVKGETVTVWPAYDEQPLRIELWGDDVERISVVHPLTGERLGDLDATVVYPAKHYVSSAGNIERAIGSIQQELDERLEYFHSVGKLLEAQRLKERTLYDLEMLKVLGYCSGIENYSRHIDGRAPGATPYTMLDYFPDDFITFIDESHVTVPQIGGMANGDRARKQTLVDYGFRLPSAMDNRPLNFEEFLSKTGQTVFVSATPGPFENQVSDSVADQIIRPTGLVDPEVTIRPIQGQIEDLLGRVRERTAAGERTLVTTLTKRMSEDLTEYLLEKGVKARYLHSDIDSVERQVIIRDLRLGHYDVLVGINLLREGLDLPEVSLVAILDADKPGFLRSDRALIQTIGRAARNVNGEVILYADVVTPAMRFAMDETARRREKQLAYNEEHGITPRTVIKGVRDVIRGEELEGEISSENVSGDRDSLTAQLTDLELDMWQASEAMDFEKAASLRDQIRAIEAKLQGKEFKQATVPGQKARRKGRR
The following text describes a protein:
Function:
Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSFRGGRGGGGGGGFRGGRGGGGGGGFRGGRGGDRGGGGFRGGRGGGGRGGFGGGGRGGYDQGPPEEVVLVGVFSHKCQDDIVCNNTSGKIPYFNAPIYFENKEQVGKIDEIFGSPGENGFSVTLSQGVKASSFKSGSELYIDPGKLLPVERFLPQVGGGRGRGGRGRGGDRGRGGDRGRGGFGGRGGGGGGFRGGSRGGFGGGDRGGFRGGRGGDFGGRGRGGDFKRSYDGGGYGGNSNKRTKFD
The following text describes a protein:
Function:
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
Subcellular Localization:
Cell outer membrane.
Sequence:
MRRALRLLPLPLSIAICLPAMAADKPLNWGLCPAVDPLPGFDGAPAADPKAAEIRQQLPTDIEGDQLSGTSTTPQYQGNVALKRGDQFLGADNLRMDTETGNYIAEGNVRYQDTSFRMVADRAEGNQDTDSHKVTNIQYQLVDRRGNGGAESVDLQGQVGQMHRSTYTTCDPSQPIWRVRAPEIDVDNDEGFGTARNAVLQIGKVPVLYFPWFKFPIDDRRMTGLLFPQFGLSGRNGFDYLQPIYLNLAPNYDATLLPRYMSRRGFMFGTEFRYLYDGGRGEITGNYLPNDNLRKKDRGSVFYSGYHNVNRYWQARSSISWVSDTRYVEDFTSRINGMGSASSIQSTVGIYGTGETWTAGLMADRWQLTDYTLDERSLPYNRQPRAYFTWEKPFGIFEAGVYAEAVRFTHDDSYLVQPPRDGNTNGDDGDDYVRTNIRNQEYGSGSRLDLKPYISMPLSGSAWFLTPTVAWRYTAYQLDSTLANTAPLTGDRSPTRSLPIASLDAGLYFDRETSLFGTKYLNTLEPRAYYLYVPYREQNDLPVFDTRPFTFSYGQLFRDTRYTGADRQNDANQLTLAVTSRWLRQDDGREKLSLSAGQILYFNDSLVTINNSTNAAAGSEQTIEQGKSAWVADANYMINDRWSMGATYQWNPNSRKEDLASLRTRYLLNNDGIINLAYRYRRNLIDESDQLKQADFSFLYPINPTWSAVGRYYYSLLDRKPLEIIGGVQWDSCCLAVRALVRRFVRNRDGEMDNSIQFEFVLKGLSSFGQNTDRTLRRAILGYYRDDLYLVPPSNTTTNPDDYDPNLIP