lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Receptor with a serine/threonine-protein kinase activity (By similarity). Together with SKM2, LRR-rich receptor-like kinase (LRR-RLK) required for male fertility by the perception of CLE43 and CLE45 peptides and the transduction of their promoting action in pollen tubes, especially under relatively high temperature (at 30 degrees Celsius), thus conferring tolerance against high temperature probably through the maintenance of mitochondrial activity. Seems to not be involved in the perception of CLE45 peptide in roots.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MSTSHHHHHPPYLITTLFFLFLNFSCLHANELELLLSFKSSIQDPLKHLSSWSYSSTNDVCLWSGVVCNNISRVVSLDLSGKNMSGQILTAATFRLPFLQTINLSNNNLSGPIPHDIFTTSSPSLRYLNLSNNNFSGSIPRGFLPNLYTLDLSNNMFTGEIYNDIGVFSNLRVLDLGGNVLTGHVPGYLGNLSRLEFLTLASNQLTGGVPVELGKMKNLKWIYLGYNNLSGEIPYQIGGLSSLNHLDLVYNNLSGPIPPSLGDLKKLEYMFLYQNKLSGQIPPSIFSLQNLISLDFSDNSLSGEIPELVAQMQSLEILHLFSNNLTGKIPEGVTSLPRLKVLQLWSNRFSGGIPANLGKHNNLTVLDLSTNNLTGKLPDTLCDSGHLTKLILFSNSLDSQIPPSLGMCQSLERVRLQNNGFSGKLPRGFTKLQLVNFLDLSNNNLQGNINTWDMPQLEMLDLSVNKFFGELPDFSRSKRLKKLDLSRNKISGVVPQGLMTFPEIMDLDLSENEITGVIPRELSSCKNLVNLDLSHNNFTGEIPSSFAEFQVLSDLDLSCNQLSGEIPKNLGNIESLVQVNISHNLLHGSLPFTGAFLAINATAVEGNIDLCSENSASGLRPCKVVRKRSTKSWWLIITSTFAAFLAVLVSGFFIVLVFQRTHNVLEVKKVEQEDGTKWETQFFDSKFMKSFTVNTILSSLKDQNVLVDKNGVHFVVKEVKKYDSLPEMISDMRKLSDHKNILKIVATCRSETVAYLIHEDVEGKRLSQVLSGLSWERRRKIMKGIVEALRFLHCRCSPAVVAGNLSPENIVIDVTDEPRLCLGLPGLLCMDAAYMAPETREHKEMTSKSDIYGFGILLLHLLTGKCSSSNEDIESGVNGSLVKWARYSYSNCHIDTWIDSSIDTSVHQREIVHVMNLALKCTAIDPQERPCTNNVLQALESTSSSSSSCTTYLSKILSLA
The following text describes a protein:
Function:
Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA. Possesses both single-stranded and double-stranded DNA-binding activities. Involved in early microspore development, but does not alter meiosis or tapetal cells development. Possesses Holliday junction (HJ) resolvase activity in vitro. Cleaves HJ at symmetrically related sites of the branch point.
Subcellular Localization:
Nucleus.
Sequence:
MGVGGSFWDLLKPYARHEGAGYLRGRRVAVDLSFWVVSHSAAIRARSPHARLPHLRTLFFRTLSLFSKMGAFPVFVVDGQPSPLKSQVRAARFFRGSGMDLAALPSTEAEASADALVQPRNAKFTRYVEDCVELLEYLGMPVLRAKGEGEALCAQLNNQGHVDACITSDSDAFLFGAKTVIKVLRSNCKEPFECYNMADIESGLGLKRKQMVAMALLVGSDHDLHGVPGFGPETALRFVQLFDEDNVLAKLYEIGKGVYPFIGVSAPNIDDLPSPSTKSLPRARSPHCSHCGHPGNKKNHIKDGCNFCLVDSLENCVEKPAGFICECPSCDKARDLKVQRRNENWQIKVCKRIAAETNFPNEEIINLYLNDDNLDNENGVPLLTWNKPDMEILVDFLSFKQNWEPAYIRQRMLPMLSTIYLREMASSQSKSFLLYDQYKFHSIQRIKIRYGHPYYLVKWKRVTRSMISNDPPSKQTELEGKNDKVEVLDGDDEVVDEEEEEPTMISETTELLDEPDVPQVLDDDKDCFLLTDEDIELVNAAFPDEAQRFQEEQRLKEAKSIARKSKLNVAGFETPKGPRPSGVQLSIKEFYRSKKGLSGDSGKDGSRKSSDVDLSKNLPKSVRRRLLFD
The following text describes a protein:
Function:
Probable DNA-binding regulatory protein involved in cell-fate specification.
Subcellular Localization:
Nucleus.
Sequence:
MESSRTAATSTNGTEKSRRRNTDYLQIDPSSTFINNTGRGFAEELPENFLDTISPHPITPSASTSSATSATEEPATSSAPQLASLAPMSMSSEQPSSSFSSASLLSSSYETIKNEPEFSGSTAGLLSPLHVDSRRRESHDFNTSPYIKEEEDLDGSHLLMGGIRPDTPTNDRSTDLGSISSLLNEDHHTNTIGQSPSPRSTFGSDPTPMIQRQLIKNEDGVSPGSMGFSKNHQGYQKPRNGDRMEYEKAPYQRNSRKQKKPLGLLNQALSSVISTPTISSSNIPTPPSAHIAQPRRIYSTQDSNDPLNAEIGDDIYIDTKDLCKRIAFELKNHSIPQAIFAERILCRSQGTLSDLLRNPKPWNKLKSGRETFRRMYNWVAQPLATRLAILDMKTEDVNRASGMSPPTPAQNVRTHRRSTSDHDGPVSKRPRLVFTDIQKRTLQAIFKETQRPSREMQQTIAEHLRLDLSTVANFFMNARRRSRLGGNIDEPTPFQQVKNISPPPVGDTSDALLNGDDHVPLLNTVMAEMYKEGAIATSNHSAEQREMIERGFGVSIPGPSHSGELLNGDSHEDDEELDELNDSELAYEEDVEIGDEEEEDEEQANGDILPTPKVEELEEKTVIKEEAPDDGEYGATKLAAN
The following text describes a protein:
Function:
Required for intron-independent turnover and processing of mitochondrial RNA. It is a key control element in nuclear-mitochondrial interactions (By similarity). Required for embedded hyphal growth, for wild-type respiratory growth, and biofilm development. Required for chlamydospore formation, distinctive morphological feature of the fungal pathogen C.albicans that can be induced to form in oxygen-limited environments and has been reported in clinical specimens. Plays am important role in virulence.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLLCQKPTYRLLRYSVKRYVASLYSLRGVSTRVNLIHRTYATTVAKDNIDHNDSSPVFNNNEVRFENINASIHPILLDLKNKLIKGKFDSPYTILNDQPSDVKTEIFQSFEQQLSKALSSKSTPENKITLVDYLNPTLDNISSLLHLISNNTYPNNFLEFSNLSSNNDLIMQLFTQLLHKIFLQYRIENASFEKPKVDFSNPAEWFPEARKMKRKIIMHVGPTNSGKTYNSLIKLSKSKTGYYAGPLRLLAREIYEKFNSQGIGCNLITGEEVVPSIDKYGKVSGIASGTIEMIPLHKKMDLCVIDEIQMIADPLRGSVWTNAVLGVLAHEIHLCGEESAVPFIQKMVEITGDELEIKKFNRLGKLTVEKSNTSLQQLKKGDCLVVFSKKKILKFKCDIERNTRLKVGVIYGALPPEIRSQEASKFNNGEYDVLVASDAIGMGLNLKINRIVFSGVNKFNGSTVEKLSVSQVKQIAGRAGRFSAQHGSKEGFVTALHRSSLVYIDQCLKTPVSEISKACIWPTSNIWRQYMANDPHKSSLSSVYENFLTNVLKFQSDNFFISELDQKVQLLNLVAKNRLLSTMIIDDQLTISETPINFRTSVNPKLLKNTVIKFYETIVKRDCKSILDFDFLDLELLSQNSFVGTDVMVPLQKVDKLEDMHRLVLLFLWLSQRFPTLFIDKDSAMEVKALVEKRINQELVNVERANSFFSDRSNGYEPRR
The following text describes a protein:
Function:
May direct the termination of translation in response to the peptide chain termination codon UAG. Required for normal chloroplast development and plays essential roles in the termination of translation in plastids.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MNSSMTTSPTARAFLHLHSSPFTLRSRKSPSGVCLVSWPPSRSRRTRRLVCMAEPYLIRKMESVEKTWKELSVKLADPDVVSNQSEYQKLAQSMSELDEVVTVFRRFKDCEKQLLESKVLAKEAGDDEDMAEMIGSEINSLTKEIEELEKQLKVLLLPSDPLDARNILLEVRAGTGGDEAAIWTGDLVRMYQRYSERSSWKFSMVSCSEAEHGGYKTCVMEIKGNRVYSKLKYESGVHRVQRVPQTETQGRVHTSTATVAIMPEADEVEVVIDPKDIELTSARSGGAGGQNVNKVETAIDLFHKPSGIRIFCTEERTQIRNKARAFQLLRAKLYEIKVREQQEKIRNERKSQVGTGARSEKIRTYNYKDSRVTDHRLKMNFALTTFLDGALEDAVQACAALEQKELMEELSESVAASSATSG
The following text describes a protein:
Function:
Controls stomatal patterning.
Subcellular Localization:
Secreted.
Sequence:
MPRLPVGTLCMRCSSSFSTAMERLIVCRRNRGLAVFAAIIVLFFSATIAVTEGRPTRRVPTTVPLRHMRKTGSSPSALLIRGSTSSTDADDAAAAGSTPRRRLAGPGSSPPTCRSRCGRCTPCRAVRVAIQPGIGTQWEYYPEVWRCKCGSKLYMP
The following text describes a protein:
Function:
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
Subcellular Localization:
Cytoplasm.
Sequence:
MAPKRQPDPSPPQSGTLDDMSPARDHFPESAEPLRHRMMLVQDAVSDCPYIDGEPARMPLYYPTPPRRSDDTDTLLAAGFRRSSQFVYHTNCPNCRACQPTRLRADDFQLTKSLRRVLKKAERELTWSWQTPRVDADRVRLYNDHRNLRGLAHDGDISASDYETFLIASCWPTLELEIRHQDQLVGVSIMDIGRDSISAVYTHFDPIASKFSLGTFAVLQQIQWAKDNGRTWVYLGLYVAENPHLNYKSRFVPQERLIDGQWRVCLE
The following text describes a protein:
Function:
During the asexual blood stage, phosphorylates translation factor eIF2alpha in late schizonts resulting in protein translation inhibition. Plays a role in trophozoite differentiation into schizonts.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MYNKGINICLNEDNKCIILLHIIFNKCIVSFVASHILVEGKICFLNRIKNSKIFRRFGNINNHRRNNVKEYYKFVGRINKGKEKRNKCRIKLHRFYEYAKSYILKQIKWVLNKSKYIYFNIIYHLKTICYLKNAFFLQYTQRKYFSQNIENYIINSLPKHIQSFNPIKWSYYNNNEYASNYIIINNLNFIKYKNKYEKQYDIEMEEDINCKGANDIFYNSYNYCNNNNSNSKCDEKIEKNIVDKNIENKYNIKEYDKTNKSILFPIEEEFKKIIQIENNIERNYMVPNESNKNILYNIKNILEKIRNIEAISNINNYIDMKNTIESYKLNPDKCKEILHKDKDFRNKSKLCLSCFHNIIHKIIYYSKMENISFSDMYKQLLTNYNNTSCEYCNLINNSINSNNDFLSLYNDKNMYNWKNCEKNKFETLENEISCWNFNSSYGNHFQHIQKNSKIYRRILNEENEKAFNNIVGRNEMENDELYKRIHTENNYANQFTENNVDFGVYSDLREYNNGNEKYMLDENEMDQIIDEEVKKQEKNQNLNNMDFNNVNKKYNQLKDDNIIIFNKNNMHNNLYSNGLNDSNLEKNNILFPYEKYNNLDKNEMNLTKYSQNKQFYGQYKYDEAIYKYDLIVLDTSGYIYKVSTDGTYHWKYRIVKNIQYYINYEEENKIENYYNAFKKNNGKINMTHKDILRKNDYEQYHKLKLRAMKKLQYNNFIDVFNSNYKKNYPTYLNEQITEKDDIYKKKNYNYEKSKKKSKNKNAMKKLLSDYSGDLFYVDENNEAIPININIKDVVNNSPFKSTLFPNILFIGSRQSSIVNLDFDTGYVIKKYEENYDDLVKEKQKALPNKYEKFINKNSNVLHDKLEKYLDHSIDINDKNYYVNEEKDDLDKDYTIIDGKVAENNQQLDNIDLYNNEIETENNNGINHLLLIDGKGQIEEQSPNNGNKIIKGDVSNMTDECGTENCLSKHSKEEIEIANNKFNKNNKDKLLIQRTKIKNKKHFLMGKWYMNISNNNLLNINSSVLGINKKKRNSKKGENRNKKRKTQKRQLQISLVKWVIKAVDETSLKQKWITSWVDVGSIFITDSHKQDLSFINSLIDIDGNKLILRTLENNKVNKPYNNTISKNIEDAERNELEFASENYKNDIPNEIDEHNNKMGRNMNKLNSNIKSKIFIFSKEISSVFALQYKSKTNIFTLDTILKQNEKLFPEYDNIKPYSYNLLNLKNNSNALLLPFSSSNDYLKNNDKKNLPWNFNYDENGTNANNSIAFQNYNNFIVQRLNNISINITSIEKDLRYLLLSIIFVFDKHKKIPMNYIFQMKTLLHEYQKTKQKFMICLRGLNHNKNINIFSNHNDIRDTDIKHYGYNDYDYINKEMDAIDEPIHICEYTNKFIDLSFEGKEKCIDYCSMLNIWDKIFNNYTNHDDCLLLSNLYRILNSTYPLTNKDFNRIIDGIFLKNNESMLIKRRRKPNEGSRNHDLTEFSSQKHKKSWYWNIFYAITLVIVIPFIFIYRLFKKQTNNKNNNKIIMRKKKITDYDEDSNDTYDDELLNIDKVLLKRNKRKLANILKENGISSLNKTELEKYMKKSLKKAQDIEQLTLVDILARHARDSDSDSNFYDIHDGKYNLYPYYYSGQESKYSLPNMHYIDLSKSNSGETNKYDLNGNNLFYMHRRRAASQDVTYKQSFIVKKRVRSNYKLGNKYNKRNYTDYEKDKKNSSIKERNINEKAFDKSDFINFLKNFNKKFMKKNPFVDHLMKNNKTDSNNEFNNDNKEKSKYLYNEKYNLNSADEENKSPYAKKYSDEKKNRSKSSKYIENTQSNNNDNTNGNMNVGNHINNDKMNNKGSSARNLSIIQTSHIPYDAPLADFLENGRFTRTFQNISLIGQGGFGSVYKVSHRLEPGSPTYAVKFIYLKVSSLDNVNSRRYFREIAANRDIYSKHVVRYYTWWCEEPQFLPMDIIPKEIQNTLKKNKDPFKKVCNKNKKDNDYSSDCTVSSGENNKFDLKNYKKVITKKNSPKLKFYSDNDTPYNKRKNINQKNSFLNDKNLSDNIYIIENNKKKKKKKKKKKKIIYKEKKKGNIGINEDNKYSTFYEQNNPNNFSSTLQEYDPFGYGYLSENERDLIVFADNDESNGSGHSKKNDNDERKSLNNQNGIYNTGGDISKNGNVIHDDSNMLACQQSDKNSMTIKNTQGTSINGTINRNTISDETGTQGTNNNPKYSIDYHIDAIVKPKGESFTWVEKSPSNKYKKDSLDIINRNRKLIEEKNKKEKGQEKEKYKLKMNGELEKKENANKIKYYKKKNVGPEFSIVLLLQMEFCKGFTLRRWLDRSSRSDKPLYFTYGDKNTNHPLEFDLFKQLIKGLKDIHSTCFIHRDLKPENIFVDLDTYILKIGDLGLVRFIEEKKRENDLNNIDNFKDNIYTEINHNTITSQISLKGQMIGTPGYTAPEGGALCDEKADIYSAALILLELLCPRFNTIMERYKTLNDFRNYYTVPDYVKIHLNPWYILMLQMSKPNPADRPSAADLYNKIKVLLDPHLTDFTFSFNDINNDDLEYTGNRNVINSTNPNGDIKENVNQNNLVDDKGNNNIINGNEVDH
The following text describes a protein:
Function:
Acetylates the N-terminal alanine of ribosomal protein bS18.
Subcellular Localization:
Cytoplasm.
Sequence:
MPQVFDLERRSFNDSSWTIDAFYHEIEQNNFAKYFVLEFEQQIIGYLGLWIVIDQAQITTVAIDDNYRGYGLGQMLLKYGINYASHTCDVMSLEVRVNNKVAQHVYENLGFQYGGKRKNYYGEGEDAMVMWVNLND
The following text describes a protein:
Function:
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MPPGRFGSNPTLSLKLALISSLIAGAAAFAPAPVAKTSTALNKVAFNPEMAGEVFDPMGFGKMHEIKGAFPNMFPNPQFLEESEIKHGRMAMLAWTGVWATESGLHFPGAPVADDWTTALGVWAREDPGGFGIVLLLLSIAEGEGVSHAGDNFRGVSKKTPGDMGFDWMGMTKKLSADKLERYQTVEKKNGRAAMIAMASLFAMKAIPGSVPIMDMLGAN
The following text describes a protein:
Function:
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Sequence:
MKLFAFCVIAVTLSCAYGWGDCHWKILNCAESRVNQWINDQIAVELKGHYTYLYLSKLFERESHYYPKVAKYFRAKSNEEMSHAERFIEYQNQRGGTFDITLVQKKSDGSCANVNSILTGFKCAKELEIDVTDALTLLQSKVTSVQISESCYNNASGTTGNDLARAQPIVIHHHNEVSKPLSAYTCPHQLPTRVTVEYVELTEMIVHEFLGHQIEDTKEIANHVKTLQNIGDVNAGLGSFLVDKHLEL
The following text describes a protein:
Function:
Insulator DNA-binding protein. Chromatin insulators are regulatory elements that establish independent domains of transcriptional activity within eukaryotic genomes. Insulators are proposed to structure the chromatin fiber into independent domains of differing transcriptional potential by promoting the formation of distinct chromatin loops to form topologically associating domains (TADs). Recruits Cp190 and cooperatively binds to chromatin promoter and insulator regions to exert transcriptional regulator and chromatin insulator functions. Recruitment of Cp190 leads to recruitment of Chro/chromator and chromatin decondensation. Chromatin binding sites often cluster with those of other insulator DNA binding proteins that can recruit Cp190, such as cliff, ZIPIC, CTCF, BEAF-32, lbf1, lbf2, insv/insensitive and, to a lesser extent, Su(Hw). Together with Cp190 and CTCF involved in regulation of the Miscadastral pigmentation (MCP) insulator. Cooperates with cliff and su(Hw) to recruit Cp190 and regulate insulator function at the front-ultraabdominal (Fub) boundary.
Miscellaneous:
MISCELLANEOUS: A pita/spdk mutant was first identified in a P-element insertion screen for mutants with a mitotic phenotype. The highly condensed mitotic chromosomes characteristic of the mutant resembled the pieces of fruit in the British dessert known as spotted-dick, after which this protein was originally named.
Subcellular Localization:
Nucleus. Chromosome. Note=On polytene chromosomes of third-instar larvae colocalizes with Cp190.
Sequence:
MAAKLEVREAMLTEKRVCRFCLTEQKLASIFEENPRVKTTANLPLQIMAITAIEVYAGDGMPGHICLECRLLFEHCYRFKQMCKRAETLLRQYPLTGNWPSPLEKPRAPMTMVASKKLLVVPAKTAEPSETPKKLLNTMAKSSSQVIIEDVQVLESAMVTPRTVAGSSPVPRRSHAYELKVDNNQELSMDDVQSMLEDMASELEKEFPDIPQKASPVKPKVLNKSSIRILNKGPAAPVEPRLATPKVKRDDSGNVAIVTEVLDSDLPLDDQDDPTKNAEKVATDVFPCPDCERSFPLQQLLEIHRLNHTRSRSFQCLLCEKSFFSKYDLAKHNFVHTGERPFKCAICSKAFTRKALLHRHERTHTDVPKFICVYCEKPFLSRQEMEKHAERHQKKRPFQCGVCTKSFAFKQGLERHETVHSTNLPFPCQHCERSFSTASKLARHLVAHAGKRAYPCKYCHKSYMLSHHLSRHLRTHTQTSDASFVCSECKVSYSNYNDLLDHALIHATASLKCPMCRKQIEDIDSVESHMDQHKQSERHACEFCDHIFLTQKCLQRHIEDDHVVEMEPYQNEFEDDGEGEGGVDEKEEHLDDFEDMDNVKQEEFVTEYLEDDALYEDHLDDSDESFTPPPPKQRKTNPPKDAQQSVRQTRSRDAQRITQKTGKNEGKPHHKLERNLKNRRSAK
The following text describes a protein:
Function:
Escort protein required for cholesterol as well as lipid homeostasis. Regulates export of the SCAP-SREBP complex from the endoplasmic reticulum to the Golgi upon low cholesterol, thereby regulating the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. At high sterol concentrations, formation of a ternary complex with INSIG (INSIG1 or INSIG2) leads to mask the ER export signal in SCAP, promoting retention of the complex in the endoplasmic reticulum. Low sterol concentrations trigger release of INSIG, a conformational change in the SSD domain of SCAP, unmasking of the ER export signal, promoting recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi: in the Golgi, SREBPs are then processed, releasing the transcription factor fragment of SREBPs from the membrane, its import into the nucleus and up-regulation of LDLR, INSIG1 and the mevalonate pathway. Binds cholesterol via its SSD domain.
Subcellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MTMGKSTLPWFAGKPLLSVLQFVITVKLKPWNAGLQSNEVLRVALKPAFLVTNSLMDYQKNGIGLPDMCLHVASHGAIRQRSGLRLRDSQFLPAEGCLLLSPANLWNKSLERFEEDDHLVDDLYQEHGRPAINIALKEFIFGVPLKHTGLHPQVKWSGHEHNIRYAVTLMLNPDEPSFVEGLRNHLWKQFPGMVHEDHGSQVVHIYYKGEGGSLVELGPISVAYFVVFLYLAFSVAKIDMVKSKWGLAFSAVITVIASLIMAAGLCTMFGLVPTLNSSEIFPYLVIMIGVENILVITKSVVSTPVDLDVKHRVAQGLSKEGKYMLKNLLWEILVLGLGYLTYVHAIQEFALFALVGLLTDFFLQVFMFATILSIDIRRMEGILLRQRGRLHSSTTEATSNVQPVHLLPPLPPASVKSPGTPHPSTALPLRKSKRLEIAYFWASTRIVQKALMVFAVMYFLYMVFFVPSTLSTADEQGPNPDDESLIEKMIREAFQDSATKDHAIPDPDRPLSGTQGHKSMQQNLDQIPQSASWTSLSNKHWPQLLSYYDISLVGRYISLLPAVHIHVNINTLELASSGNTRQDPPLTTPIPPELVEAGSGDEAEALDPEYYLNALYCVLLGMLAMIILFFICKYLNDLQISPRIAGRGRRTTGSHDELTEAVPMRLIGHPQNVEHVICTLSGIVSICLSGEIRVWDRSSGDCLRVVNRMGRNPIRPRRRRRPSSRGAKRPFGWDEHFTTARYFESLVTQDADTQENPEMQPDPSDPIGDPVGIPVSGAHKSTDIKRNYSGSFGSSTSAASGFDFSPYCQDRGSPGISPWPWSSDEESSVSEGSCKEEETDGVDESKIPPPCGPSSSVWCLDCRGDILATGCSDGSVELWSLSSGRQICVYCENRQGVTSVTFLPNSPQVVVARLDGTLDFLTLISPTASSVMFSLDASPVKRTSSPRMSRKPLSPESGTSSVSGDPLNPTHASPTMCSLTHRVRAHHQPVSVLVASEGRVVTGSHDRTLKVFRTDHCVRIFTLHGHRDGITELKVDSNNPDIVISGASNGGVRVWDLSTGECLQHLRGHTCAITTVASTHAHLISVSIDNSMCVWERSTGKCLHYNLRQIPDLCSNVAMLTGNLFVTGGQGVIVVWDLLAGKPVKCVSLGNGDSSVFVRNVLVCDTATVVCEFGKDLRVVTFPFVTNKAE
The following text describes a protein:
Function:
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24A may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
Subcellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
Sequence:
MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMFTNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLLHVQQQICK
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors (By similarity). Plays a positive role in wound-induced activation of jasmonate-responsive genes whose promoters are targeted by MYC2.
Sequence:
MVDKLIVAVEGTAVLGPYWKIIVSDYLDKIIRCFFGVDSTSQKSSAADVEVSMVMFNTHGPYSACLVQRSGWTKDMDTFLQWLSAIPFSGGGFNDAAVAEGLAEALVMFSVPNGNQTQQKMEGKKHCILISGSNPYPLPTPVYRPQMQKLEQNENIEAQTDSRLADAETVAKTFPQCSISLSVICPKKLPKLRAIYDAGKHNPRAADPPIDTAKNPNFLVLISENFIEARAAFSRSGLTNLASNHSPVKMDVSSVLPVSGTQSISNSAANVSVISRPPISAGNIPPATVKIEPNTVTPMTGPGFSHIPSVRPALQPVPSLQASSPLSVSQEMVSHTENVQEMKPIVSGMTQSLRPVAAAAANVKILNGVAQAHQVLGGGTSIGLQSMGGTPMLSSMISSGMASSVPASQAVLSSGQSGVTTMTGAVPLAGSAQNTQNSAPSSFTSTAPSMSGQTVPAMSQGNIPGTQMMPSGTGMNQNMLTGLGATGLPSGTGTMMPTPGMSQQGQPGMQPVGVNSTSANMPLSQQQTSGALPSAQSKYVKVWEGNLSGQRQGQPVFITRLEGYRSASASESLAANWPPTMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLSQLQEKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDMVVFKPQIPSQQQQQQQQQQLQAQHPQLQQQQQQQQQHLTQLQQQPLQQLQQQQQQQPLMQLQQQQQIPLQQSQVPQMQQQQIHQMQQQQQIPQMQQQQQIPQMQQQQQQQPMVGTGMNQTYMQGPARSQLMSQSQGSSQGLPITPGGGFMN
The following text describes a protein:
Function:
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
Subcellular Localization:
Cytoplasm.
Sequence:
MDEKLPESVDVVVLGTGLPEAILASACARAGLSVLHLDRNEYYGSDWSSFTMTMIHEVEENKVFLGHHKTSRPSFQVPKLSEEEISKLSAHLLESEKLVELGNREVIENIQRTWIPRDSDDVPIKQKLEEMGQMRRFSIDLVPKILVSKGNMVQTLCDSQVSHYAEFKLVNRQLCPTQDKNTENSAKIMLNPVPCSKGEIFQSSVLSILEKRALMKFITFCTQWSTKPTEEGRQLLGDYSDRPFSEFLAQMGVAETLQSFIINTIGILQPNPTAMSGMLASCEFMDSVGHFGPSPFLFPLYGCGELSQCFCRLAAVFGSLYCLGRPVQALVRENDRITAIIANNERINCRHVVMSPRFVPKDVPIQNVQKIERVVFATDKSIKEVEKEHLTLLNLASLRPKSTISRLIEVGFEACTAPKGHFLVHATGTQSDDDEKSVESLAEQIFEESQVSPYWKMSFTANSMKFDAEGAGLGSNVVVAPPVDANIHYSSVIKECRKLFCSTWPDLDFLPRAIKNEEDEEEKEASESSETV
The following text describes a protein:
Function:
Required to maintain the prospore membrane to the nucleus during sporulation in order to capture the daughter nuclei and form the spores. Mediates the fusion of exocytic vesicles with the plasma membrane during sporulation through its interactions with the t-SNARE SSO1 and v-SNARE SNC2.
Subcellular Localization:
Cell membrane. Prospore membrane. Note=Membrane-associated to the plasma during vegetative growth and prospore membrane associated during sporulation.
Domain:
The inhibitory region sequesters the protein in the nucleus; The positive regulatory region is essential and contains an amphipathic helix with hydrophobic and positive charged faces involved in the localization of the protein to the membranes through its binding to phospholipids.
Sequence:
MGFRKILASKSHHSRHHNQHHKNLKLQNHRYVLISNITGSHETKYLSPFRMDNCSGSRRRDRLHVKLKSLRNKIHKQLHPNCRFDDATKTSDDKCVSYEVPERDGLATISLEEVFPKSNRCQIPEENLGETDSVIHRDLGNFANENDYPQWRKVESQYNLENVQPEEDEIVDRLRSEIRSTKLKSVKTTSRTLEKAIEARCTGKRVLQQLSCQSNQLTKIESNCDMLKIQSNVADRKIDELAHENRSLLALKSPNPFRKKREREKRDQIYNLKLKHRHLQQETMKRAQDSDKNLAINLSSEYGRYGQGVERQRILRDAQKYQFEADEEDNQMEIDLYGNLEQIKAVSGDLKIMAHAFGREFEAQNTRMFDIENNVQQADNALQAKRYRLEKVIGKRW
The following text describes a protein:
Function:
ATP-binding RNA helicase involved in mitochondrial RNA metabolism. Required for maintenance of mitochondrial DNA (By similarity).
Subcellular Localization:
Mitochondrion.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MFANSLRRITKPCLGVPDMAVRHIAMRPKPKVKVNSREGGGKGKPRPSTGVRRKPPGAQKQQPASIAINGDAARRLLESKFAANISSFNELKLHPDVRAVLPDVIQLPEHKQDQDIKPSIIQSLAVKIMRQSYTYKQRVKNEGEEPTVEKIPVDRQKTFVLAAQTGSGKTLAYLLPLLSDLKDQEKFPSWQLEKHYKTVRSVILVPTLELSQQVGQVLKQFEEPLGIKTFASAFGQSHQEIAKAFNNRLDVLVTTPQKLQQTREKNLGGATHLVVDEADTLFDTNFIDSTTDVISQMPKLKCAAFVAATVSKSFLRKLRSFYPHVVVIAAPRLHAIPDHIRFSVVDVNKAPYYNNKKVALLQALYAISHSQKQKNYVRRVVVFRNRKEHIPELKKFLEENGYPVDTLHGKQDLHERNEVVEKYTNMPDAADQTENARNVRVLLTTDIASRGMDMKNLRFVVLYDVPFDKTDFIHRVGRTGRFGREGEVYMFTDNQDKKAQTNQLLHTSRNGLSL
The following text describes a protein:
Function:
Golgi serine/threonine protein kinase required for intermediate growth in the proximal-distal axis. Phosphorylates specific residues within extracellular cadherin domains of Fat (ft) and Dachsous (ds) as they transit through the Golgi. Acts in ommatidial polarity determination as a secondary signal downstream of Notch, JAK/STAT and wingless. Also necessary for the initiation, up-regulation or maintenance of Notch ligand, Serrate (Ser) expression in legs, thereby participating in a feedback loop with N signaling. Sufficient for joint formation and growth in the leg.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein. Note=Golgi apparatus, in the wing pouch; [Protein four-jointed, secreted isoform]: Secreted.
Sequence:
MYDIKRLEAGQQKLQQAQQPLGLDLSGQQQQLTCSVITAPEHRANPNPSSISQSNPSEATHMTLLTLRRRRSLQRRACLLSILAAFVFGMALGVVVPMFGLPRHQDSPPDLPEEQIQMVAVEPLSSYRVEFIKETDELSAEQVFRNAFHLEQDKDAPDSMVVKKLDTNDGSIKEFHVQRTASGRYRKGPERRLSKKMPERVQPQETSRSPTTSPTNPTSEHQAGFIEEDVYWGPTVEQALPKGFAAKDQVSWERFVGEQGRVVRLEQGCGRMQNRMVVFADGTRACARYRQNTDQIQGEIFSYYLGQLLNISNLAPSAATVVDTSTPNWAAALGDITQAQWKERRPVVLTRWLSDLEPAGIPQPFQPLERHLNKHDVWNLTRHMQSERQAQSQPHGLLKRLGAASSPGSAHQSNAIEETGTGTETANGALVQRLIELAQWSDLIVFDYLIANLDRVVNNLYNFQWNADIMAAPAHNLARQSASQLLVFLDNESGLLHGYRLLKKYEAYHSLLLDNLCVFRRPTIDALRRLRAAGAGRRLRDLFERTTSAGVRDVLPSLPDKSVKILVERIDRVLGQVQKCQGS
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MKPPILLIILLTMISGTMIVLTSSHWLTIWIGLEMNMLAIIPILMKKSNPRAIEASTKYLLTQATASMILMMGITINLMFSGQWATSKTLCPTTSAMVTTALAMKLGLAPFHFWVPEVTQGTHLSSGLILLTWQKIAPLSVLYQTSPTIDPNLLLPMAITSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAVTLYNPTMMLLNLTIYIIMTTTTFMLFMYNSTTTTLSLSQTWNKAPLITPLILMLMLSLGGLPPLSGFIPKWMIIQELTKNEMIIIPTIMAITALLNLYFYMRLTYSTTLTMFPSTNNMKMKWKFDNMKKMILLSPLTVVSTMLLPITPLLSILD