lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Localization:
Nucleus.
Domain:
The F-box is necessary for the interaction with ASK proteins.
Sequence:
MLEDRSPDSCLSTRVFSSSRLSESNWSNSYMYPEDDDKLLGNGKRALEVVGEVRQTKSLKLMGFSIIYDSDSSDYSLSGGEEQADAAIGDGSSSRQEQEQQSDFNDNGGDSSDSHSLINEIGRDNSIDCLIRCSRSDYGSIASLNRNFRSLVKSGEIYRLRRQNGFVEHWVYFSCQLLEWVAFDPVERRWMQLPTMPSSVTFMCADKESLAVGTDLLVLGKDDFSSHVIYRYSLLTNSWSSGMKMNSPRCLFGSASLGEIAIFAGGCDSQGKILDFAEMYNSELQTWITLPRMNKPRKMCSGVFMDGKFYVIGGIGGADSKGLTCGEEYDLETKKWTQIPDLSPPRSRADQADMSPAAEAPPLVAVVNNQLYAADHADMEVRKYDKENKKWLTVGRLPERAGSVNGWGLAFRACGERLIVIGGPKCSGGGFIELNSWIPSDGGPPQWTLLDRKHSPTFVYNCAVMGC
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil.
Sequence:
MEKRPRRTPAEKARAQYTNYAVKEPMELMEFLAAKMPDASRTKLKSLLSKRVVLVDNVITTQFNFPLQPGMKVQISKEKGKKEFHNRLLKIVYEDAYIIVVEKMQGLLSVNTERQKERTAYTILNEYVQRSGRQHRVFIVHRLDRDTSGLMMFAKDEKTQRTLRDNWHEIVTDRRYVAVVEGTMEKDYDTVVSWLTDKTLYVSSSDYDDGGSKSITHYKTIKRANGYSLLELDLETGRKNQIRVHMQDLGHPIIGDGRYGGEESLNPIGRLALHAFKLCFYHPVTGDLMEFETPYPGEFKKLFLKK
The following text describes a protein:
Function:
May be involved in membrane protein folding.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGSNTSPGQADPLESENESSLTSRFLPNKRDGGKDNESVIPEKEEPDLNEPVLAVPLPKSRYALTKRSSSSEYPRRSASTSAKKNVIPITRSYSTTFFSKTNDQPTVTGNQDKPISRLRASKLQIQNFWNYICFELLANDTVPANPIKEKHVENFLATPYAIEKTFLFGWFVSVDSFLYIFTLFPIRVLISFFTLSRCIFQGLFSTFFHRNSSPNRSLPRSRKIDLLKLLLIFSTSILIRKIDVSRLYHIIRAQASIRFYVLYNVLEIADRLCCALGQDVLDCLFSNHILSFNFWNPAGWMTFFYYFAISLAYMVLHTLVLLYQIITLNVTVNSYSNAVLALLMSNQLVEIKGAVFKKFEKENLFQLTCSDVVERFQITIMVIIIFLRNLAELYTTSSLDQPLLTFKRLKTLLAPFFWVIGSELFVDWLKHAFIIKFNYIKPSIYSRFTDVLCHDYVASGAQLTQTVTGCSQQVARRMGLPVLPLVCVFIRTSMQTWSMFRSTHSMKQEIAKSIGTIFPTKDNYVYYLPNKEANTYNAGKEASWETLLLSVVRGKSGIAFLFFMAIMLKLLLGKAILAITQSRYESMQQREEKINSWERERKANNFFRGHIEIDKKTKDFLNNSKDDLPVPKSPLLTLERYAMHSKRIW
The following text describes a protein:
Function:
Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate in respiratory regulation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MWLSHGRRSGPSGGGVCAAAADDDDDGCSISSLMKSDSFCMNQSFPSARNCTLSRMDTSGNSQVSSSVAMRNLQISDLQCSLSVSPSSAAASPVLESSLLRQLISTAPEKRSTALTINPNKAVLSINSSTSQVLDANEHACKLFECAYSDLMGRKLTSLLRSSQMLEVLKEEALDSDGNLVTISSKVVTAVSLTGAEFSVSVWLQIPEKPQQILELLLERVERITAHVTFTQNGGILSCDATFAHLNGYQAAEEMTGLSIISLMPSLQIPFHCRTTPKVLRVQRLCVQARSGLVVPACVRLQAAVSCGRSPQQINGSGGKSGAGELLSPSAGVLYSGSVCVFAPSSCLLTLLPNGTIHSLNNPFSFLLLGYNSSQLLGKNVTYLIPAFYERVRAADRNNHPHESTSPSDSHAEPCRYSAGAKCPLANVLTLSTDMTSTRDDQQDTCHPNTVLAGDSVMVHLAMRRRAGLVKGKRIFTGTSAKLEKENSVLSTMTSPAVTSTPLNGLDDTTELCEQIVDVVPQTSGSDSANSTNALLQTFALVESLEVQKICTSADVSARCGPSEHHIAGQDSSKAPNPDCKEAAVNFCKYAPNPQSHTQTCLCSDQAQLQDSSFEVISLGSGSSSGFCERLMGGSGPEKLDESQQGRQHLETGSTFLDLNSNGDVIVHAMSEMDLNDSVEIPNVPADLNHSLTSCDTAELLRTPSPFVVESDVDEAAPVCPEQETTTKTPEDQERPASPQMKIPEQLPKNHLTRVLEQWSTFSDHAVSRVLDLQKKGVLLPGDAPATSTPKKAKVNSSIPEGRTHVTCYNRDGAPIEVQCDVRWVSLSSGSSLVCLWLSGSHLLLHHQEAPQSTMSPTLRTRTSEQSSLVEAVRSDSLRSSVDLEQSGACEGHFEKNYRPLRSIGKGAFGFVWLASRRSSGEEMVVKFIRKSAVVSECWVDDPDLGRVTQEVAILVRLQHPNVVKVLEVFENQGFFQLVMEKHGEGLDLFEFIDMQPRLDEPLASYIFRQLVAAVSYLRSKKVLHRDIKDENIIINSNFHIRLIDFGSAALLQPGKLFYTFCGTLEYCSPEVLMGNPYEGPELEMWSLGVLLYTLLFSENPFCSVEETLQARLNPPCEISTDLYALLAGLLHPAVDQRMTLEELLQSQWIQQPINLAEYSWRDIFPSSDDSKSSCVHRAEVLYTNSENNLSSLEDTPIGEDDDDDEDDEEQRRTMAALQSELLKYLTDE
The following text describes a protein:
Function:
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response.
Subcellular Localization:
Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Sequence:
MKKMAAISPKEIGILSSVIFLCYWNSLFCGFVFDDVSAILDNKDLHPSTPLKKLFQNDFWGTPMSEERSHKSYRPLTVLTFRLNYLFSELNAVSYHFLNVVLHAVVCIVFLKVCRLFMDTKISLLATLLFAVHPIHTEAVTGVVGRAELLSSIFLLAAFLSYTKSKGPDNSIVWTPIAVAVFLVAVATLCKEQGITVVGICCVYEVFIAQGYTFPVLWDTTLQILMGKGSIPYSMLQTLLKLIVLMFSTLLLVVVRVQVIQSQLPVFTRFDNPAAVSTTPARQLTFNYLLPVNAWLLLNPSELCCDWTMGTIPLIESILDIRNLATLLFYFLLGYLIVFSVRYSGDSSKTVLMALCLIILPFIPASNLFFPVGFVVAERVLYVPSMGFCMLVAHGWKKLSSNGRLRTLSWIFLALVVFTHAIKTFNRNWDWESEYTLFTSALKVNKNNAKLWNNVGHALENEKNYERALRFFKKATEVQPDDIGAHMNVGRTYKNLNRSKEAEESYLIAKALMPQVIPGKKYAARVAPNHLNVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLEAREAYIKALELDRMNADLWYNLAIVYIELKDPSEALRNFNQALELNPRHKLALFNSALLMQESGSARLRPEAKRRLLTYVEEEPHDANGYFNLGMLAMDEKKDTEAEVWMKKAIQLHHGFRSALFNLALLYSQTSRELEALPVLDELLRFYPDHSKGLILKGDILMNQKKDIKGAKKCFEKIVEMDPNNVQGKHNLCVVYFEERDLIKAEKCLVETLALAPHEEYIQRHLSIVRGKIMALNTAGQSVPPKEGALTLPEQEKKQVEEKGKKKTPIKKLEDESNVPKANPPSRSKIGHVKSKPQQEKNIDREGQKKSTKEIKDIENKRVAALKRLEEIERILSGE
The following text describes a protein:
Function:
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
Sequence:
MGLPWGQPHLGLQMLLLALNCLRPSLSLGEWGSWMDASSQTQGAGGPAGVIGPWAPAPLRLGEAAPGTPTPVSVAHLLSPVATELVPYTPQITAWDLEGKVTATTFSLEQPRCVFDGLASASDTVWLVVAFSNASRGFQNPETLADIPASPQLLTDGHYMTLPLSPDQLPCGDPMAGSGGAPVLRVGHDHGCHQQPFCNAPLPGPGPYREDPRIHRHLARAAKWQHDRHYLHPLFSGRPPTLGLLGSLYHALLQPVVAGGGPGAAADRLLHGQALHDPPHPTQRGRHTAGGLQAWPGPPPQPQPLAWPLCMGLGEMGRWE
The following text describes a protein:
Function:
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is involved in meiotic sporulation through regulating IME2 expression.
Miscellaneous:
MISCELLANEOUS: Present with 259 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Note=Localizes to centromeric and flanking chromatin. Association with these loci is dependent on STH1.
Sequence:
MVEQDNGFLQKLLKTQYDAVFHLKDENGIEIYPIFNVLPPKKEYPDYYIIIRNPISLNTLKKRLPHYTSPQDFVNDFAQIPWNAMTYNAKDSVIYKYAILLESFIKGKIVHNIRKHYPEVTYPSLGRIPEIFAESMQPSDLSSNPINTQENDEKAGLNPEMKMAFAKLDSSITERKPTNQDYRMQQKNSPAFPTHSASITPQPLASPTPVVNYANITSAHPKTHVRRGRPPVIDLPYVLRIKNILKMMRREVDQNNKTLTLCFEKLPDRNEEPTYYSVITDPICLMDIRKKVKSRKYRNFHTFEEDFQLMLTNFKLYYSQDQSNIIRAQLLEKNFNRLVRIELSKPDEDYLPEGELRYPLDDVEINDEKYQIGDWVLLHNPNDINKPIVGQIFRLWSTTDGNKWLNACWYFRPEQTVHRVDRLFYKNEVMKTGQYRDHPIQDIKGKCYVIHFTRFQRGDPSTKVNGPQFVCEFRYNESDKVFNKIRTWKACLPEELRDQDEPTIPVNGRKFFKYPSPIADLLPANATLNDKVPEPTEGAPTAPPLVGAVYLGPKLERDDLGEYSTSDDCPRYIIRPNDPPEEGKIDYETGTIITDTLTTSSMPRVNSSSTIRLPTLKQTKSIPSSNFRSSSNTPLLHQNFNQTSNFLKLENMNNSSHNLLSHPSVPKFQSPSLLEQSSRSKYHSAKKQTQLSSTAPKKPASKSFTLSSMINTLTAHTSKYNFNHIVIEAPGAFVVPVPMEKNIRTIQSTERFSRSNLKNAQNLGNTAINDINTANEQIIWFKGPGVKITERVIDSGNDLVRVPLNRWFCKNKRRKLDYEDIEEDVMEPPNDFSEDMIANIFNPPPSLNLDMDLNLSPSSNNSSNFMDLSTIASGDNDGKECDTAEESEDENEDTEDEHEIEDIPTTSAFGLNSSAEYLAFRLREFNKL
The following text describes a protein:
Function:
Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Active against both single-stranded and double-stranded RNAs. Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs). Cleaves mRNAs and tRNAs containing inosine. Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'-UIUU-3'. Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear: it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing. Binds branched DNA structures.
Subcellular Localization:
Cytoplasm, Stress granule. Nucleus, nucleolus.
Sequence:
MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAPYVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADISSREHIRKSLGLPGPRTLRSPKAQRPVACPKRDSGESSALC
The following text describes a protein:
Function:
[Isoform 2]: Acts as a transcriptional corepressor for AR-mediated transactivation function. May act as a transcriptional regulator during spermatogenesis and in particular, during meiotic division; [Isoform 1]: Acts as a transcriptional coactivator for AR-mediated transactivation function. May act as a transcriptional regulator during spermatogenesis and in particular, during meiotic division.
Subcellular Localization:
[Isoform 1]: Nucleus; [Isoform 2]: Nucleus.
Sequence:
MYRSGSRSSVSSHRSKDGSASGPPPGRPVGASSGPTRRPSSPPPPSCSSLRLPARRHRSPSGHRGRWASPSPPRGRRGSPSPPRGRRASPSPTRGRRASPSPPRGRRGSPSPPRARRGSPSPPRSRRHYPPGLGGFRGSIRGESRADFARDGRGDHPGGGGGSRRRSPGLCSDSSLEESLRITVGNDHFCVSTPERRRLSDRLGSPVDGLQDMDRDDLTDDSVFTRSSQCSRGLERYISREEGPLSPFLGQLDEDYRTRETFLHRPEFSPQSSCHDELLRGTERNRDKLKSSSYSIRSEERSREAKRPRYDDTEKVHSSGGDHSSFTSGTRNYRQRRSSPSPRFLDPEFRELDLARRKREEEEEQSRSLSQELVGVGDDQIGCSIPGLAGVLTTSEPGYSLQRPEEVPMMPKKSILKKRIEADMKPSLQLESFSSGASSGEDHPLYSEHSPLPLSGAIAAFTSEIENKGTTVEADLKEPQSNLYQWGPLREIPKDNSEKFDSFLGFKEKLDLKAEGLEQQTDFLLPHERASQDGSGFSRILSMLADPTITQEKRRRSFPDIEDEEKFLYGDEEEDIKSESPLKSLEDPESAGTRQKANSLPSTPAVKLESLEESNPEYAKIHNLLKTIGLDIGVAEIGKLAARTQERLHGKKPSSRPSADRRLSADRHLSGDRHFSADRCSSVEHSFTADWRSSDPHRPESRETHHSNTQSPEVSHPHPASPVDPYLRTKNSPPFLKSDHPVCHVSGPEVVGSGFQSSVAVRCMLPSAPSTPIRLPHSAALSQFHIPGASQFAAARIPPNYQGSVIPSASFDAYRHYMAYAASRWPMYPASQPPSHPLSDPHRLLPVTKQAARSRPNLRVIPTVTPAKPKQEIPVLGSISVKRIPVRVSIPSLIKYNPKKISDEKNRASQKQKVIEEREKLKTEQEARQKKMFYLTTELERLHKQQGEMLRKKRREKDGHKDPLLMEVSRLQDSIMKDIAELHKETEEAEKKQSELDKVAQILGIDIFDKSLKSSNDSKESTEKPEKEKSKSPEKELSPSNSSSSNKESKMNEKSCIKSPSSTESLQPTVKQSDQPVAAYEYYDAGSHWCKDCNTTCGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDTVKRTDKITVPAKGSEFLIPVTGFYCQLCEEFLGDPISGEQHVKGHQHNENYKKYVEENPLYEERRNLDRQAGLAVVLETERRRQNELKRKLNEKPKEEKIEKKARIVREVKEDDKAPGELEEQLSEDGSAPEKGEVKGNASLRPQVKEEVKKEPSVASIAASFGKFSWKKPEKEEEKGSVVTPGAPKEDTVETSKDRDDGKAEVGKAKPIKIKLSGKTVIAHTSPWTPVVTTSTQTKIRPNLPIPSTVLRKSGSATVSKPAPLNTFLSIKSSGTSTKPLPVVKESSSDLLLPPDIISKAFGGEEVVLKGSPEEKVELAEKNEPSQVPEQMLALLPPPPPPPPPPPPPPPPPPPQAVPQLSAPSPAQANVVLTPVKSNSVISQTFSLGFQGPNILNPGLPVAFMASEQPTVIPSDETAPGVSESDWDQTLISMLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGKGAHETKLSSSTLANGESSSLPRTESSDFSSTCTLNSSMSSEDLPQCSALVTATEISNLENPISKGMESTGKWSVVDQIDPKSRDSTYSFLQPLTRLYQNKPYEIVSPKTDTLVMWTSGSSQNDTHKDRPPEGKIRFDLGEPGPPGTDSTSHLSDTHCQTNGPQKLIEINLIDNQNKNQEVYQSEGCRESEMKRKTELKGKVATEEEEEEEEEGANSIEDSNSNHGNRNTWEGEIGQPKLSTVDKKGEQSSKLMTGHENTSKVVIELSPSLPSKRTKIDLFPSLLQNPKSMPELLLLSPAGSGLCLKRQEIWERPEKPGLEDVELQGTRPELTVTIESKVLENFDTTHLEVEGFASLRNLGDMHANFHNSQTEQTRRSPTALSEKMSEEISVSSVMCNPSSSSDIEPVPSFSGFPLESPKTLVLNFETEGAHSSSNSRNGRITSNSLETGHPVENVGHDLGGERTHQALDLLAGGMLSEDVKETSPLQKDLLRMESTTVSPSGLGPSPCLPDLVDFVTRTPGVPKQKPCSPLSEPDAFLKCSSLEMGSPPPEILSVSVSEVAVPQVSEDNDSALNLVKTPPSGSPSRDQVVGGNVSPREMPEQEAAVDVIPDHTRSNVYNSQDYLNG
The following text describes a protein:
Function:
Component of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Binding by the elongator complex stabilizes microtubules and promotes their growth. This induces central spindle asymmetry, promoting polarized signaling endosome trafficking during asymmetric cell division and cell fate assignation of sensory organ precursor cells.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During asymmetric cell division of sensory organ precursor cells the elongator complex preferentially binds and stabilizes microtubules on the anterior side (pIIb daughter cell) of the spindle.
Sequence:
MTSFRKRTVQKPIRGTRTSPHTAQVITSSGNPYLDVVIGGGLPMGSICLIEEDRFMTHAKVLAKYFLAEGVISKQEIFLGSLDDIPAEMLRRLPRPLTDQESMEQSEVQALGDAGAENGLRIAWRYNDLPLVNSEHATAKIGHHFNLMEQMDSMMLYNVKTTLWDDSPKHLDIVIDEEFSKSSSPTTPSLEQQPVEDAPPIPGTETAPQEKMPAQEEENSANNNNNNNNNSSSVTSSTKTGSQDSPLQVFHNPRYKGLLNDIQQLLRNESFVAGTKNNLCRVCLTSLGSPLWYDEHFGEDLIKFLTLLMASVRNCNSVCLITMPMHLIAKYDASLVPKIRQLVDYAIELESFAGSERETHPAFKEYSGLLHLHKMSAINTLAVHMPETPDLAFKLRRKKFIIEKFHLPPELQESSAKPDNCISGLLSNSNATASLDF
The following text describes a protein:
Function:
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
Subcellular Localization:
Nucleus.
Sequence:
MPPRKKAKASAASTPLGDTQPQTPQASGPTQSQDELLNEPWADEQETQLFKSMMKWKPTGLHKHFRMISIHNDMRSHGFVTEDAPHTRIPGIWKKLNQLYELDALDERENQYAFSEDPDPDDPDEAVNIPDFELPEDEFGELMWQKRFHREDSAAASSPAVTSIEDDKTMYHPGVGLLKDRPGSARSQKAETPAEATPTPKNAKTTRASRATVKSAKGTKSGTSATRNSKAQSTVSESAEDEEEEEEEEESNAESEEDSAPTTRRTNRSRAPKQPPKRTRKR
The following text describes a protein:
Function:
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MKLSSQASAPLAANNLTCPKILRHIYSNVHSLGGLLGIIIGRASIECGAQNASAGGCLASLSPQHGGAHLDSVAGEVNGCECGPRIPRAGTGQKGRESKNPNEHERSNIQKPNSETTTGSVHCRAGPKSRGLVLETDPEDHRVRLLEETFVVLNERAPQFRGGRSGEDDHGWTQTELVNRAIELHFQKGGRPSDLLCQGHQRAGAHVRRQGQPLPNTSGVECLGLSSAFAAVTSPPWELLLSRIGAPTMLHLLRNSSIFVPLPNGCLLQVCGRPITDLVWKKRLQPSAPLQRDPPQPANVSRKRKSARVADSSCGPEGSAHVRFVDGKRRRPTQPKGGNERREDGCARAAKQRAKAGSKRSLRETISFCGGRAVSHEVAERPDRKQKSGKFRNDEEKASVLDGQSHPALTHLSESEDVSEGPLSQEPVVRRMRGGAEGQNPCHVARFEAQGSIGQKAALERLRGASGGARGPGGGLEDVMRNKCDKGAAGLRKRGERLGEPVAEGRPEDLTPCLEPIHVRVSPGLSRREFGGSRADMDCASPAEPSDKDFGPLTQEESGREPEERPSEGTAPDAGKRKRVRESSWQRKRRRRAAAERDATSERASLEGLEGLEEEPVTQEPALAGAWKKSHRVVIQGKGASVAVSRRKTPGVHEVERFRRADQSNCLPNSCETASVRRFGPGGRIGTRAEERDPFRSDLKKRPLDQTEPMLPRRSEARSSKPGAATQRPAAPAKGSPTVRAAKSGPRLLPRAAMFYNASHGRKAGLPTSHILSSLGTDGAAAKALVWHVFEPASAAPMIAQPKPRTSFQAAFGSVRPETATGAANTEAKEWRAPRQLQAVLPLFRDLLVLVKKLDLGRLLARHCPLPETLRKTRGDRRPHAGNAKRGGKEEERGRDGECPESGPEPDLPSTCKPDSMTGVERRFVAGLATGLASEASGRRLDREEKERGGPVEASRGSKEQGEDADCMSVQGLSDGYLTQDEEDRGRVLEWRGGQDENEDECMSEDENPRHEAGSNYAFEKTGSVAQQEAEAGNSRHGNAGDVEQNRAFSCAPPSQHSAGDSGGLAALLPTHLAPDATYKQLIGQFCEHCHVAAFVWTALRKAVPGALLGGPRGSASGRALRGHVNRFVRLGRFETMSLTELMHGLRLADFPWLWEGDSRSEGVVPRGAPGGGLERSAGDGGMGGSGGLATGELQSGVVLAGESGPVEVTGRVQAFLRENAWLPDAVGTGSPFHFDADVPLTQEPQIRVSHTQSPLQAAPHSTPAKQMPKFPPEKTAALRRRLSEWLYFLFASLVVPLLRSHFYVTESEPHKQKVFYYRKPLWRHLAALSVRHLAGPGGPYCHVSAGSAEALLASKGRVFGPAEMRLLPKANGMRPIARLGAKSVVRIETRADQRSVSTAGVRSPFRRRNSLGGLQRRRNGLEGGHVREQRWSSNSFGHQQDVSGRESAGLGPQADGFERVADIFGRGSTTVGRKRDGVGRNADGTGRNADPFGRPGARGFAGAATTAASCPLPTSKVLEFGAPNKLLGDAHAILKLEKWRGSEDLGCSVFGFDDIHAKLRGFVRGLRTKPGAPMPKVFMAGCDIAAAYDTIPQEFLWQIVQALFRSPVYQLLWNARATPAFGAVRVRGEKLATSVDVSEPHVAYRAFQEALRRLTSQKAGGAVFVDQVNCSEISRGKQLQLIREHLFGSVVRYGRAYLHQRRGIAQGSILSTLFCSFFYAHLENNVLMPLLERKACEEALSGGSGTEPDSGTELVSGRAGAKSGDRASGGEPGVGQQDGRFGSERNGRGLNGMISPDRPQESDVSEAVLLRRRSKSEEANVTAGLGAGLGEGFGAGRPLEEGLFPSSPARALSDGVNEPPEPRTPEHDGTEAWLRMESSETESEAEGPDGGFSGGVEIDSGEGGCFWEIEQGYASQDEGTSPGERGWGSVGRGDDWPGREPPWETTSRQRVTTCTAPLERAPKTGTTRAEENRGESRNIGTQLERDAAAGGTSDHGVDRRNEKRPAPANENGPRSSGSGPQSLLMRWVDDSLFLSTSKRHVAAYLGAMHAGFPAYGAEANPAKTCLNFDLNDEQGGLRAQNMYVDGSGRSFIRWCGLLLNSETLEVQADYTRYSGEYIRDSMAVDVTKGRRGAILADRLCLWLRPKCHAVFFDTAINSPTTVRLNIYQAFLLCAIKFHCFLSASGGDPRSNPEFLAREIWKAIGYLSAAVGTAREAARRRGTGCSGKVSKSQVLWLGLRAFRRVLSRKQTQYQPLLKLLADDFGREAKQLSETLSAAVAPDLSAVFDQILY
The following text describes a protein:
Function:
May play a photoprotective role within PSI in response to light stress. Forms a trimeric complex with OHP1 and HCF244 that is required to promote PSII core subunit assembly. The trimeric complex forms a transient PSII reaction center-like complex with PsbA, PsbD, PsbE, PsbF and PsbI subunits in thylakoids for early assembly of PSII as well as PSII repair. The trimeric complex is required for the recruitment of ribosomes to the psbA mRNA during PSII biogenesis and repair. Forms a heterodimer with OHP1 that binds chlorophylls and carotenoids, and that may function in the delivery of pigments to the PsbA subunit of PSII.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein. Note=Associates with PSI under low or high light conditions.
Sequence:
MSVASPIQCIRILNPSSSSSSSTASSSFRFSTTTKPCVFIIRCSQTEGPLRRPSAPPTLREPQKPVPPSQPSSSPPPSPPPQKAVAVDGKSVTTVEFQRQKAKELQEYFKQKKLEAAGQGPFFGFQPKNEISNGRWAMFGFAVGMLTEYATGSDLVDQVKILLSNFGILDLE
The following text describes a protein:
Function:
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
Subcellular Localization:
Cytoplasm.
Sequence:
MTLGITEVKKGMVLKVEGDLYSVVKTEFVNPGKGSAFIRTKLKNLTRNSSIERTFKAAEKLESVELEKRNMTICYTEGDDIIFMDSNDFEQMPVSKEYVEDILPFLKEETPMEVTFYEGKPIGVIPPNFSILEVTYAEEGLKGDTSGTAQKRITVETGGEINVPIFVKQGDVIKIDLRDLTYVERVSK
The following text describes a protein:
Function:
Hydrolyzes ribosome-free peptidyl-tRNAs (with 1 or more amino acids incorporated), which drop off the ribosome during protein synthesis, or as a result of ribosome stalling; Catalyzes the release of premature peptidyl moieties from peptidyl-tRNA molecules trapped in stalled 50S ribosomal subunits, and thus maintains levels of free tRNAs and 50S ribosomes.
Subcellular Localization:
Cytoplasm.
Sequence:
MSNTIKMVVGLGNPGKEYEQTRHNAGFWFLDELAWKWKASFKEEKKFFGEVARAALPDGDVWLLKPATFMNRSGQAVAALAQFYKIKPEEILVVHDELDIPCGRIKFKLGGGNGGHNGLKDIQAKLGTADYYRLRLGIGHPGDRNLVVGYVLNKPSTEHRRQIDDAVAKSLQAIPDILAGKWEEATRFLHSK
The following text describes a protein:
Function:
Required for oocyte nuclear envelope breakdown before entry of oocyte into spermatheca. In meiotic cells, required for spindle dynamics and probably for spindle attachment to the chromosomes. Zygotic role in the development of the germline and nerve cord. In mitotic cells, plays a role in spindle organization and centrosome maturation. Involved in asymmetric nuclear localization of cdc-25.1 during embryogenesis which affects cell division timing. Together with plk-2, regulates cytoplasm polarity in early embryos. May play a minor role in chromosome pairing and synapsis during oocyte meiosis I.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Cytoplasm. Nucleus. Chromosome. Chromosome, centromere, kinetochore. Note=In mitosis, remains associated with centrosomes entering prophase through to anaphase. During metaphase, embryos show anterior enrichment and located to the chromosomes of the metaphase plate. In meiosis, detected at centrosomes after pronuclear meeting in post-meiotic 1-cell embryos. Associated with chromatin during chromosome segregation of anaphase and in the region between the dividing chromosomes. Cytoplasmic in mature, unfertilized oocytes. Asymmetric cytoplasmic localization is regulated by mex-5 and mex-6.
Domain:
The POLO box domains are involved in the asymmetric cytoplasmic localization.
Sequence:
MNRLPNIAKPPQKSNQRKEKAPPEVPALIADKDRGTYYEKGRFLGKGGFAHCYELTNRATREVVAGKVVPKSMLVKQYQRDKMTQEVQIHRELGHINIVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFTHQIVDGVLYLHDLNIIHRDMKLGNLFLNDDLVVKIGDFGLATTVNGDERKKTLCGTPNYIAPEVLNKAGHSFEVDIWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAASLIRKMLDPEPTRRPTAKQVQRDGFFKSGFMPTRLPVSCLTMVPKFGGHETSMMEENVAPRGVDARSQRPLNGRAGLSALPQHIVSNNADRERAQQQAAEATFREPEDAYLSQLFHQVAVLLEQRIPGLEEEEAALDGYQSPECLPVFWISKWVDYSDKYGIGYQLCDNSVGVLFNDNSRIMLDQAGNELTYIEKSNKEHYFSMHSGEMPGLLNKKVTLLKYFRSYMNDHLVKAGEGSEQRAGDDLARLPTLRVWFRTKSAIVLHLSNGTVQINFFNDHVKMMMCPLMQAVTFIDQNKRMLTYKLNNLQRNGCPEKFLHRLKYAKTMIERLMSDANVVSQNPARQPDMPRSMAAARSASAGSRGPNQAASHLPQSASGSNIHPRR
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
LILSPTRELALQIHTQAQILTSSHANSRNSHTYRMSSQVMYGGSSRRVDLEKLQDNLPYVLVATPGRLIDHMKNSRVGNVPFSEIIGGVSVLVLDEADRCLDMGFRSDMEWIIDVMKEYEQKEQHEEYRHQRQTLLFSATLPKDLRSIMASSMRKDYVTVDCIHDVDPTSHTNERVDQTFLTLPSFVSGKRHANDLYHIIHIQNPTNYKLVVFFPTTALAQFFSYLFNKIYNIPVIEIHSQKSQSNRTYNSNLFRKVKSGVLFTTDVSARGVDYPNVTHVIQYGSAENRETYIHRLGRTGRAGKRGVGILVV
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Subcellular Localization:
Cytoplasm.
Sequence:
MTDSKTEAAFKPVELYTDGACSGNPGPGGWAFVLRCPRTLKEIQRSGGQPHTTNNQMELMAVIRGLEALKEPCAVDLYSDSKYVGQGMSSWMAGWKSRGWKRKDGSKLVPVKNVELWQELDQQMQAHRVTYHHVKGHAGHTENELCDKLAVAAYQQYL
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEWARKWWLANAFMVPSVLRVLFGLPAVIVVQQTLTFPGSVSGRISNFATAHPGAFRGLFTMMVLLLSSCVGFGTYWHWSDETSLTNGIIASSDCRSQNCAKSKRAFSMEVIVAFVLPLLVTVNIYLYRWNNRAMIADLNRNFRCIYDSHQHSLHAQRQYCFWDQYGRLVMKQLFEVMALGVLWLNLRPLNHTEEGGNVDNYWIRKLISSMAAMLPAVVCVLVSIEMGIIFSFIARTLTILNWSLDSWVRCSCADNGLKRLRKSTLIQHLQASDEWSPYTMDIRGYLRKCIAKYDELCQFMLEIVQFYSSNLLLIIGMHFILFTMQVCVKYLFLYWARTNRSLDHRSLLTNLLFYFVVFICKKWYILLELYHQTLFLCYRQMSRTTSVSANLNDTLFPMLSAIASAGQIVFLVDMIANVNSKVTIFSLIVRNVLDSTNLYGYFDLDRSLVMTIIASTCSYLIVLIQVM
The following text describes a protein:
Function:
Involved in the activation and reutilization of phytol from chlorophyll degradation in plant metabolism, including tocopherol biosynthesis. Catalyzes the conversion of phytol to phytol monophosphate (PMP) (By similarity).
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MAAAAAWTGAASPNSLLLSRSPPHAAALAPSPGSSMRRRLLLGVGTPAVAALAAAAPPAVLQDGAVTVLITAGAYSLVRVFDELTERRLIEKSLSRKVVHVLSGVLFMSSWPLFSNSTEARYFAAVVPFLNSMRLLIYGLRLYTDEALVKSVTREGKPEELLRGPLYYVLVLLFSVLVFWRESPIGIVSLSMMSGGDGFADIVGRRYGSAKLPFNRKKSWAGSISMFISGFLLSAMMMLYFSSLGYIDVIWEEALGKLALVALAATVVECVPVTEVVDDNISVPLATMLVAFLLFSSNRTIVN