lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation. May be involved in apoptosis signaling in the presence of the retinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation (By similarity). In association with CALCOCO1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells. Can act as a both a coactivator and corepressor of AR-mediated transcription. Contributes to chromatin looping and AR transcription complex assembly by stabilizing AR-GATA2 association on chromatin and facilitating MED1 and RNA polymerase II recruitment to AR-binding sites. May play an important role in the growth and tumorigenesis of prostate cancer cells.
Subcellular Localization:
Cytoplasm, perinuclear region.
Sequence:
MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAVLQQQYSQPQQALYSVQQQLQQPQQTILTQPAVALPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLGAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPTAVIQPIVPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQDLRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPNPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKKADGEQDEEEKDDGEVKEIATPTHWSKLDPKAMKVNDLRKELESRALSSKGLKSQLIARLTKQLKIEEQKEEQKELEKSEKEEEDEDDKKSEDDKEEEERKRQEEVERQRQERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKDKEKKSKKEERKDKKEEREDDIDEPKPKRRKSGDDKDKKEDRDERKKEEKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEDDDREEEEVKRDDKRDVSRYCKDRPAKDKEKEKPQMVTVNRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDDENHEESEALQEDMLGNRLLLPTPTIKQESKDGEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDGKTILNLENSNKSLSGELREVKKDLGQLQENLEVSENMNLQFENQLNKTLRNLSTVMDDIHTVLKKDNVKSEDRDEKSKENGSGV
The following text describes a protein:
Function:
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
Sequence:
MVRFKELAELFEELERITSHKEIVRKLAGFFGGLKGDEVKDSAYLFLGSIGPAFENTTLGIKDRLVTRAIAGAYGVSEEEVKKRYARAGDLGDVAFELSKKREASLTIEEVFKRLRQIKEASGKGSQEKKTGLLSDILQKATPEEGKYIIRIVLGRLRLGFGDQFLLEAFSIAFTGDKKHAGKIKESYSVCTDIGELAQTLAEHGAGAPGYFSIKPGRPVKSMLAQRVESFEELEERIKGKKAAEEKYDGERVQIHKAGDEIKAFSRRLEDITAQYPDIIEAVRESISADTIVLDGEIVAYAELEKENTRIEEFYPFQNLMQRRRKYEVEKYREKCPVAVFFFDILYLNGESLLKKTYPERRALLEEHVNGSGIVHLTRRTVTENIEELEDFFNETVEKGLEGIVAKSMSSNSVYEAGKRSWLWLKWKQEYSEGMRETFDLVVVGSYYGKGKRKGSFGALLCAVLNEEEQQFETFTKVGTGFTEADAEEINSLLSAHTVSEAPKNVIIKKGMLPDIFIEPAVVIEVLGSEITNSPGHTAGEGEEETGLALRFPRFLRIRYDRAPFDATTVREIRDLKEGI
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MVVLAASICSRGGKAIISRQFRDLPKEKVAGLLAIFPKLIQGSKQHTTVEHDNVRYVYQPLEELYVVLITNRQSNILQDIETLRLLVQVVTSLVRVVDEREILLAAFDLLGAFDEVVSQGYRENLSLQQIQTFLEMESHEEKIQEIIERNKELEATEDRKRKAKQLEMQRKEAAKRGLPGNAGGHGSFQAPAFQAPAPSFVQPAAAPAPIPETTHKPRAPRGKGMQLGKKKGGFDDSPSASLLANADIAVPTPKSKPQQQTAPAAAAPSAYNPEVQGVHLTVAEVVTATLGRDGSVKSAEVKGDVQLRIGNPDHTKIRIALEANAPGVKYRTHPNVDKALFSSRQIIGLKDPSRGFPSNGAALGVLRYSANAPEEAVPLTFNCWFAKSDPGFYDVTLEYEVSEGFTGKMTNVSVIVPLVSSNAHISDSSITWDQFDDHLEWIIPEITADGDTSTGAFEFTAEADQEDEFFPMEVSFTLNDPETTVGNVKILNVFSATAEDENIPYQEVTRVTSDNYQIV
The following text describes a protein:
Function:
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
Subcellular Localization:
Cytoplasm.
Sequence:
MEIDNKIIIVDKILEQKIVSKDFNCTQCDKLAFLPNQCLNGHIFCSSCIKNNKSCSVCQIDFGNGLKIAKNLYVEKNILNMEVHCLNYFKNLNSYIYEKEEGGCSQIMKLSDLKLHLELCSFKYVKCQYSKICGSIRKNLLPTHEKACQFNLVPCKFCKVEIQNNSMDNHIAIECEEAQISCNRCYQSIMKKELVNHWRDSCTQYSHKCVYGSFGCSKMLKRGEMEVHENKYNHHKLISSFMKKCLIVKPVYYQLRLDLFPYLILTKKFAKLTTDRYILNFEYISNLLFKMSIQIKNNFKEDFNLNIHIYSIFCKVLGSSTCTKMKENIAYEFNGDINKTLDLEIILKEQENYHPIN
The following text describes a protein:
Function:
Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.
Subcellular Localization:
Nucleus.
Sequence:
MSIIQDKLGNEFLRSNGSMDSNFGAGMIMFSHLPPVTSFTRLAAHTVMQDLPPQEMVFKKERDSPDCSVVTQRANLGVGDYVHALGIKQEKQSEHDYRLPLYPGGLGKSTGLLGETISSNQNLLVHDLNMGSLRDDIREMLPSQLEKEATGRKGRRSNGDGQEGKPRKRRGDAKERDGGSLSPGSKPHICEHCAAAFRSSYHLRRHVLIHTGERPFRCSQCNMSFIQKYLLQRHEKIHSGEKPFSCDQCNMRFIQKYHMERHKRTHSGEKPYRCESCQQYFSRTDRLLKHKRTCGDGVRKGLEPGMMDLDCMNVGQGSYGITQGNAGRKKGRSRNSGEGEERKKKKGDGRELQMHGSVSGGYGVHEYSGEDQAVSSSTEPGPSSQQGRAPKKASRKGPGKAATQQAKAGSLEQDGVMGDLGLLQGNEAKVESTSSNYDDAMQFLKKRRYLQAANAAGHQSSEYDIHLSSQPSVTQGGLSNVLESDAPLSLDKSGIPDEVLQSLLDHYSQKPGGGHADMHFDLSDQHVELAPTAASSPDISTSDKSVMMNEYSRFLLQALERTSHSFSMGPGPPPSGPFTSSHPGNPLFADKSIYTLSPLECGFGPAVASPSLPSSVPKSHFAMLTGSSPQHCFHLSLEAPTHQQLTPSQELTEQMEKHQASTPPSSYQISPSELSGRKDQPPLKSGSPAVYTLVSSQDLTSLDSSKTSYQIENFAQAFGSQFKSNGHSLSFGTDSSGDVDHRIRTPVSEFSGYSSLLSDVNEPVSTGSSTPTSQSYR
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MLFCPLCANMLLIDPDLQDTRYFCQTCPYIFHIKNKVVTKVPLQRKIIDSDVFGGEEAWKSADVVEVECQVCRYRRASLIEIQVDPIGQPKTSYYRCKNPGCENQWQKKNI
The following text describes a protein:
Function:
Plays a major role in single RNA editing events in chloroplasts. Acts as a site-recognition transacting factor involved in the edition of the site 5 of ndhB1 and ndhB2 (ndhB1-5 and ndhB2-5 sites corresponding to cytidine-830), which are plastid-encoded subunits of the NADH-plastoquinone oxidoreductase. May provide the catalytic activity for editing site conversion.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MASSPLLATSLPQNQLSTTATARFRLPPPEKLAVLIDKSQSVDEVLQIHAAILRHNLLLHPRYPVLNLKLHRAYASHGKIRHSLALFHQTIDPDLFLFTAAINTASINGLKDQAFLLYVQLLSSEINPNEFTFSSLLKSCSTKSGKLIHTHVLKFGLGIDPYVATGLVDVYAKGGDVVSAQKVFDRMPERSLVSSTAMITCYAKQGNVEAARALFDSMCERDIVSWNVMIDGYAQHGFPNDALMLFQKLLAEGKPKPDEITVVAALSACSQIGALETGRWIHVFVKSSRIRLNVKVCTGLIDMYSKCGSLEEAVLVFNDTPRKDIVAWNAMIAGYAMHGYSQDALRLFNEMQGITGLQPTDITFIGTLQACAHAGLVNEGIRIFESMGQEYGIKPKIEHYGCLVSLLGRAGQLKRAYETIKNMNMDADSVLWSSVLGSCKLHGDFVLGKEIAEYLIGLNIKNSGIYVLLSNIYASVGDYEGVAKVRNLMKEKGIVKEPGISTIEIENKVHEFRAGDREHSKSKEIYTMLRKISERIKSHGYVPNTNTVLQDLEETEKEQSLQVHSERLAIAYGLISTKPGSPLKIFKNLRVCSDCHTVTKLISKITGRKIVMRDRNRFHHFTDGSCSCGDFW
The following text describes a protein:
Function:
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Subcellular Localization:
Cytoplasm.
Sequence:
MNQSKEVRTRFAPSPSGFLHVGGARTALFNYLYAKSQGGKFILRIEDTDQNRSTEDSFKIILESLKWLGVNWDEGPEVGGEYGPYIQSQRLNIYKEYTEKLLKEKKAYRCFCTQEELEAKKKQSEAMGVPYVYDGLHANMSDEEVQEKLKQGIPYSVRFKTPSKTLIINDIIQGKVKFETKLIGDFIIVKSDGFPSYNYAVVVDDALMKITHVIRGVGHLSNTPRQILLYEALGYNIPEFAHASEIVGMDGKKLSKRAGATSILAFRDLGYLPETFRNYMALLGWTSTDGREFLPGDELEKIFDVHRCSKSPSTFDVFKKPKGSDEEVVTNFSDLTQIAEAMNPKSKLNWLSNRTIRDLNISKVLENLLPFLMDRKDIPAEVKNVNNPILTSIVESVRVYLDNLTQAPDYVAEFFVTDLKIQSEETIGFLKDGEGPKVVNEFYEILKNSDPKTDEDYKNLMSKVGEVTGQKGKTLYMPIRAATTGKSAGLELPILFPLLGKEKLLQRIEKTSKETGISLSN
The following text describes a protein:
Function:
[Gasdermin-C]: This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering pyroptosis; [Gasdermin-C, N-terminal]: Pore-forming protein that causes membrane permeabilization and pyroptosis. Produced by the cleavage of gasdermin-C by caspase CASP8 in response to death signals. After cleavage, moves to the plasma membrane where it strongly binds to membrane inner leaflet lipids. Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis.
Subcellular Localization:
[Gasdermin-C]: Cytoplasm, cytosol; [Gasdermin-C, N-terminal]: Cell membrane; Multi-pass membrane protein.
Domain:
Intramolecular interactions between N- and C-terminal domains are important for autoinhibition in the absence of activation signal (By similarity). The intrinsic pyroptosis-inducing activity is carried by the N-terminal domain (By similarity).
Sequence:
MPSMLERISKNLVKEIGSKDLTPVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVEFSLNDILEPSSSVLETVVTGPFHFSDIMIQKHKADMGVNVGIEVSVSGEASVDHGCSLEFQIVTIPSPNLEDFQKRKLLDPEPSFLKECRRRGDNLYVVTEAVELINNTVLYDSSSVNILGKIALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRKQLVIKEKAILISDDDEQRTFQDEYEISEMVGYCAARSEGLLPSFHTISPTLFNASSNDMKLKPELFLTQQFLSGHLPKYEQVHILPVGRIEEPFWQNFKHLQEEVFQKIKTLAQLSKDVQDVMFYSILAMLRDRGALQDLMNMLELDSSGHLDGPGGAILKKLQQDSNHAWFNPKDPILYLLEAIMVLSDFQHDLLACSMEKRILLQQQELVRSILEPNFRYPWSIPFTLKPELLAPLQSEGLAITYGLLEECGLRMELDNPRSTWDVEAKMPLSALYGTLSLLQQLAEA
The following text describes a protein:
Function:
Required for pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MSKHHPDLVLCRRQPGITVGKLCERCDEKCPICDSHVRPTTLVRICDECAFGSSQDRCIICGAPGVSDCYYCSECTRMEYDRDGCPRVINLGSSRTDWFYERKKFKNAGKEMPGATY
The following text describes a protein:
Function:
Chorion membrane (egg shell) protein; plays a role in protecting the egg from the environment.
Subcellular Localization:
Secreted.
Sequence:
MKYLIVCVTLALFAYINASPAYGNRGGYGGGYGGGYGPVQRVVYEEVPAYGPSRGYNSYPRSLRSEGNGGSAAAAAAASAAAVNPGTYKQYAIPSYELDGARGYEIGHGYGQRAY
The following text describes a protein:
Function:
Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding (By similarity). Has minimal or no quinone reductase activity. Binds strongly to single-stranded DNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MATGQKLMRAIRVFEFGGPEVLKLQSDVAVPIPKDHQVLIKVQACGVNPVDTYIRSGTHNIKPLLPYTPGFDVAGIIEAVGESVSAFKKGDRVFTTRTISGGYAEYALAADHTVYTLPEKLDFKQGAAIGIPYFTAYRALLHSACVKPGESVLVHGASGGVGIAACQIARAYGLKVLGTASTEEGQKIVLENGAHKVFNHKEADYIDKIKKSVGEKGVDVIIEMLANVNLSNDLNLLSHGGRVIVVGSRGTIEINPRDTMTKESSIKGVTLFSSTKEEFQQFAAALQAGMEIGWLRPVIGPQYLLEKATQAHENIIHSSGATGKMILLLN
The following text describes a protein:
Function:
Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. Is able to utilize other purine nucleotides including ATP, dGTP and ITP as cosubstrates in place of GTP but with a lower activity. Does not display lactate kinase activity.
Sequence:
MNCGIKMKVIIPVSPINSLKTRLSEFLSGEERKNLLLNMLKDIIKALDGLDIVIVSRDEEILDFAKNELKAETIKEKYKGLNNAIKQAFEEIEDKEVIIIPADIPLIKKKHIEDILKLSKNYDLIIAPSRGGGTNLLYLKSKDLIEIKYEGFSFLKHLEEAKKRNLRYYIYDSFLISVDINTPEDLGEIFIHGNDTYTKNYLKSLGIDVEPKHSSAGRFVVKRR
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MLDQGAIDWDDFRFVLAIVRGGSVSAAAKQLGVDHATVIRRVDRLEKHLSAKLFDRRKTGYLLTEAGQRVADSAEAMESTIVANQEQVGGSVARLTGTVRIGAPDGFGTAFLAPRLAPFADRYPDLDLQLVATARLFSLSKREADIAISLTMPKEGRIVGRKLLDYRLGLYAAPAYLDRFPTIVSREVLPQHRFVGYIEELLFTPELDYLPQVSPRISARFRSANLIAQLNATLSGFGIAVLPHFMASDYPQLVAVLPEEISITRTFWMLMHADSKDLARIRAVADYIGEIVERERALFAGR
The following text describes a protein:
Function:
Plays an essential role in male gamete fertility (By similarity). Required for the binding to erythrocytes and thus, for the formation of exflagellation centers (By similarity).
Miscellaneous:
MISCELLANEOUS: In P.berghei, dispensable for male gamete attachment to erythrocytes and the formation of exflagellation centers.
Subcellular Localization:
Cell surface. Cell membrane; Peripheral membrane protein. Note=Present on the surface of male gametocytes.
Sequence:
MFIYLFIYLFFKMDKKRTFYYLFFFFTFLVYVLYFDNIKSVLRSSTKKKKKKKICKSTFYVHEESEEIKSWLRNSNERDKGKKFFIFERLIKERKYICVNKYKRNNKLKWIYKNTYEKTKNICDDYNILFKCIKGIIYDKNKETFFETFFENFWDNIFYMNKYIFNIYYYMFDYTKKVKKKIEGIKENMNIRHNNNYNNIFYVHKFFLFNDDEEKKKRNDDIKINIKLHNNTRKLSVSEENVELKPYIKQGERNETVVNLYEYFTGGVKRSNNNNEIVVTSTEQFHRIVIICFKPTVKHSHIITSPHDALNHIVEENDKIKLSEEIYSIPFYPIYGNLGLKNVITTGIVEFMIPYFSRTQMNFTVTCANGEMNDLYKFEDLIKIRIRIPRNTKKILGLSTNEKDKTVFERIVDNTSNEYRFKSYNNKIVGIKLENSILDPPGCFKTVYEDDKILQLEVFLQYVKCINLDRDNYKIRFFFLPEDFGDEEIEFSCKFTYKKKTSKIIFGLGETSVDKDIFYLEDEHVKLNINQDISGDEPYYSHLNYNGIPYNICNFQYKSEYDSQVCERTIHEFSLFIYNCDTLVGTQIQTTEPITSVKYLNSTYPINKFSDITLLSKDIDIEGLEEAFRNSKFFLTSYINHGPFPLIIECVISNSNKDYQNVYILLHLRTSIKNRSVSFCDFEKVQGYNYLNNYIDGKICNINITSNSVFGFRCPSNSIKEPKDCFSQVYIDKKVYKLNDKLSNKLILYSMKQENLAIAGFNNYISNSFSFECYCIDKNQTYSSYERTSGEDIFNHIVKRIHVHYKNYDELYDYNIHDKITYEPIMKNPPITYLCDFLNKKQILQPLNNKTKNYICTIWYPKPLNYIALNCPTNRRDEQNDQTISEVYNSLQKDLLKPTGIEQQIDQKKKELNLLFNKRNIYSNLYHLPKNAPKRTINKNGLNIVNIDEIIPGILIKDVINMKLEDVIKPDLLTPTSFLHKTYNTNKSYLFSTRNKSTSVFNTPSIYTPLTHTSFSISPKSVPLTKSRIEETHSSSNTYEQYIGKRNSIENGFFIFQLPPYLKKNQTIEFACINDSTIKNKNVGNNGIMTIHLKSFGNPIEGCYFYKNSAKYNYLKKSIKIDDLKKEECTIRSDGEIEFVGIMCPYENNLYLTPSSCFLKTYDNTDNLVELLDINENFEYYSNDKGISYLKIPQEFLNHVHLFCYCNVDKDSVSDTNVLVKKENKISLELNYSNKGFNIIKTIDYQYEADILIGYSYYFKRVTPIYRKKHICDFTTEDNSLEPESEDKMIYSCYLSLENNLNFIEVKCPKNKKSSNSEWLFKYGTFDKSSEIMEDDENIKKYEHMKYMPEDKDEIIYLFKKQKLEDILPGVIIFDKNRYFFEKGNFSFVTPLIVKEDVTIKLLCDNSETKIDDKIGKKGIILIKIPQHITDKKFYGCDFSGDSNKKSSFYYTSVYDLKTQNQYCEVKLKENIIISLNCPNGNINPNNCFNNVFLKTNMNEQIHEKIQNIFDQVKVINTKSHVLLNSSSTFLIISKITKKELNFFCTCHHNETKNVGTIYIKNEDIINFSKAYNKESSILQYIDVTPYYLKDTYICDFTQNHYSISFDTSVNVQNVLERYLKILSDLYNTHEEFTYFSIHLKLKKEIMKKKYIDYLKKKINEYKEKETSDKIKRVTLSTNDNINTILVYRCNIDLGSFDKFKIKCPSKLNEEEVENNKLYPNLIYSSNLGLDETDMLNGLTKLLYGSVLINKTEKNVSFFEKGELELIISPYTDSSKNIIFSCENVPRNLSKGIIGSASIFIKKNDNKILGCDFIDTPSTLSSASTLESSYGSHASSPLSSSHHVLHNDNQGHDVHMINHIDISNKKNSFEFEIELIEGKNTYCNIEAIENDIVGFSCPYNFLTTPSDCFESIQIEGVDKELETHKLEKLLKGVKILNNDIYKYNFTPSYIILPKKIKKSLKIFCRCNSVKLIKTGIIQINIVGDDLNNWFKKEITHNIFAYQKMDYFYDFSKGPTNISSENVLGISTMSLMSSNKKVSRKKNHKEENRTQQNVYKEIENDHKNINENVNKYDNLPVTLLSSDEGDGYQADEDIGGEDDAEDVDGEGDDEDDNILNPLRTKQVYDIIVAASEFSKIEVVCPLRNSSQFRQSKISPENFFEYVYVLEDKNDDKRKRSIEENEKLVKAILEGKKNIDGHIINIEDINNKKSSKNASVEYDDMGNKIFISIISEKPKAVIGDNISSSRSSVHISNNIMNSSFQSNIHPDPITSDTTTSEYEQYNSYFKDILVIKNINEVISFANIKIDINEQTYSSSLHIPPLILKDAEFLISCDNSLTLNENTRGKTATVKIKVKSNFLKIYGCDFVGEFSTHFLFSKKWDDIPKNYICKINIQDDMLIGLACPSFTKLHPPDCFENIIVNQNVYKKNIIMETKNMFFYKQNDKPILSFVHVKKILVETFLCKCYQVTKADYKEVTIQILYEPYVMGTPKYTLEKSIIQYRYANLKPPLHI
The following text describes a protein:
Function:
May only reduce GSH-thiol disulfides, but not protein disulfides.
Sequence:
MASTAASLRLPSPPLSAPAAAASFSSATTLRFPLRRRGAARPLAVAAFKKLSEASPVPIPPESAQPPLDEEALPPKPGVYGVYDAAGELQFVGISRNVRASVEGHRRKVPADLCASVKVSVADEETPDRAVLTNAWKSWMEEHIESTGKAPPGNVAGNNTWVGAPQRPPDLRLTPGRHVQLTVPLEQLIDRLVKENKVVAFIKGSRSAPQCGFSQRVVGILEAHGVDFVTVDVLDEEHNHGLRETLKTYSNWPTFPQLFVGGELVGGCDIISSMAEKGELSALFQK
The following text describes a protein:
Function:
Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MLCGGSRASVHLWDHRHPPRLGAKVLRKSSFMLRPCSAISQQRIKSSFRSHCKTPRKIPAPLDCFSQGDDHPELSAEGLSPVAGGIVALGKFDALHIGHRELAIQAARIGTPYLLSFVGLAEVLGWKPRAPIVAKCDRKRVLSSWASYCGNIAPVEFEIEFASVRHLNPQQFVEKLSRELRVCGVVAGENYRFGYRASGDASELVRLCKDFGISAYIINSVMDKNQVSVNTEEEDSKSKERGQVSSTRVRHALAAGDVRYVTELLGRPHRVISRTRTQDLTSKRGRISLQTSSLLNLPPGNGVYKACSLIVGDKHPISCKVIVDTSNLYIETEEERFHNSDESQEFQLLGIEFG
The following text describes a protein:
Function:
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MIVIIFAIISIILCNFDESMRWGTYKPQLIHAVTQRNMKTFNPITGALMYADHIGTDDRSLVYKIPDLNTEQVKINPVHHNGKDFNVQVISDPNTKSIIQTTLIKFPIESKVNFVDEIKTLNIEKPLSLFYVLTIEQFNQFNLETRTFEVNVTNHGIRVSTYNEDETRIEHFFITITVNDRNYQYNCTDEKLSNLTIRTLFNDYIFNYDPRPTLMQAIFSNSTNTNNSNLVAIEFRAQPGDNVIIQVTQTDKYIPDYGFDNLEQLSDSLAAVNRFNFKKVFGTDNKCAYSSFSNLMAGLLFTYGNLSCVINKDTCTAFKPMLSHTPSRFGFPRPFLWDEGFHNMIACKINPDICLQSLEDWINTMSIDGWIPREQPRSEELRSYIPWLKEDPRESNPPTFFFNFEYLIDNHPEYKERIGKIYLKLFSWYNNWFRTQAIFNDQGKFSGFLKWWGPDEDSNLGSGLDDWPRTDGSKVSKYNIDAQSWGYFFTFHMAKLAKLYDVGIVSSLEQRLELILNKMNSDMLDPNDLIYKDILYYPNTDDQVFYSPHRGYVNLFPLGLGLIDKSRVDIIQQQINFMRSSTMWTQFGIRSLESNSTEFRKKSNYWTGPIWVNIQFLVLRALKLYYWEIDGVQQFYRDLRSNMIETICSQYETRGYFYEHYNQNLDGLGQGNRPFNGWTSLITLIIAEKY
The following text describes a protein:
Function:
Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MTVILGTTIIQSDTEKLKKVVDTIPRFTYHKGFSPLAGGYTTDKNWGCCIRSGQGLLMQFVSKLYQLYGDKIKNIFPNGSKFELFFDHPQAPFGIHCICRELETFGVKAGEWVKPSMLAPVFKDLLSFFGIHVVIAENGCLSRESLREALSYGHPVLLLFTLMLGYKDFDLKYLPFLRLTLSLIYQSVGVVGGQQGKAYYLVGHQKENLLYFDPHEVYDSVTKLDNMNLLFKAQLKKMQSSQLSSSMLVGFYITSMQDAEELPMLLSASGECPIQIVDKIDPVKTTHVEDDWEVVNN
The following text describes a protein:
Function:
Together with wdr-48, binds to and stimulates the activity of the deubiquitinating enzyme usp-46, leading to deubiquitination and stabilization of the glr-1 glutamate receptor.
Sequence:
MHQHMLGPSTSLGGTNNSALQSSVLSEGVLLSHSQPTREEIKKNFETREGVYRSVPSAEFSRPRPLPQYHMPPGIASAAASQIAAAGSTVRVSFLNGAEKSVESPEAVAPTSSTYEHHKNEPNGARIDMVDEAQADKICFNVGKELYVFSYRGTQTETDLSRPIDKRVYKGTSPTYHAFNQESAKNGSCQLLIGFTLGQLQIIDPLEKSSSSPFSRLYNEDRYIEKTSVTCIRWLPGDSNIFLASYVSGNLYVYDQRISAASSNNNGSSQPPPWTIHKEGDKFAIHTWKGKVQRNPVTRWQIGEGSIHQFSFSGSDGKMMATVSHDGFLRIFNYHAQELLAVMKSYFGGLLTLSWSPDAKLIATGGEDDLLTVYSVAEKRVVCRGQAHKSWVSQVKFDPYLCTTEEDLENNGIAMTSTFDDVAKDFSIRSGPVPSTSADLNSGVMNATSTFSRCSLASFNTINGAPAGNSVRYRIGSVGHDTFLCLWDITEDMLNQGNIRRHRNSTIIAPMTTLEVQTNSLVGRLEDLQEVSPGGAGVNASSDSQSITNNHTTPRPEKQKKKKFTKRLGFSKFTSGSSSATSNPVGGHKIGTLMNGASVNSESSKKQNPGLISQISCCNETRMLGSKFCPGIRDVPMIEPLMCKKVSHDRLTVLEFREDCVVTACQEGYICTWGRPGRYQPKRDCINSPGTASPESGQKPSGSTSAMTSSYGYGSDALNGVPPSRSSSTYSNSEQQLRSPNITSPSYRVSAASTSVYHRPTYAWQNAN
The following text describes a protein:
Function:
Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MGKHLVEKMEIFKGNSKREIHKKIQLVTNEPYKITDERVTKLGIFKKQYEVTAVIMSEVAIADGRMDFQETFQKSVVKTRPKTDDLLKKEKLLEMLAAGAELAQSTPLLEERKTQEEELSSMRLELAALNRELAVKMREEREQNSDFVKFLKGRGISDTYVADFMQAGRKQFKQVETAHLDDITDWFVPYLSGKLAVEDSFDLSGHRIISLIGQTGVGKTTTLVKLGWQLLKQNRTVGFITTDTFRSGAVEQFQGYADKLDVELIVATSPAELEEAVQYMTYVNCVDHILIDTVGRNYLAEESVSEISAYTDVVHPDLTCFTFSSGMKSADVMTILPKLAEIPIDGFIITKMDETTRIGDLYTVMQETNLPVLYMTDGQNITENIFRPKSRWLAERFVGTDRRQVVE
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MEEQQPPSIKKKIVDFLTNFLKKRPSHEDLRRDNILVAPNNVSPAIQPSRYELEGHLNPSSHNRDDSSNNNNNNNNNNNTVEYSRGHSKSHSRSDSKHHNRENSKSDRDNSRSDNIRFGRKDTFKNAWDYLRNIDFTFSKTKYGNTVVHRLKHPQFGLSPEELQSLYPDQPHGIPIVLTKCFEYLSKHLETEGLFRVPGSNREVSLLKFKIEDGDLDFSEVLIPYNICGLISTFFKELPEPLIPFDYYNDAILITKLGSKDKYIIGLRDLVLSLPPANLCMLRKLLEFLLTVEKKNEFNKMTISNISIIFGVTLLKDPDTVDPMKSLNNIQAQSTIIKYMLEYFNDIFKEASVVKAYRKSIVPKEPMDTTSISYLDPAESNGGSPRTSNTPYQQQHQLSSQSMANIKPRPPSRSKMMRETIVLSPRVSGGNNQVYANATMTRPMSRLFFDPEIIPSPPPTTTTTTTTTTNTTTTTTTTNTTPNNTTTVNIQQKPVPPKPNLIPRKLPPNPNYSTYPAPLPPRQPNTIPLAPIPPPKPNSTYKKQITQPPPPRKPTSPSPPIATLKPTSKSDFIPSTNNNLNNNNTTTTTSSLISIPKAKPPPPKRNNVVSPAIEEPINPNLNINSTTTTPTPPLASFKNNGTISSGSKSNPNLQNLLNTNQPLVSSNGPPNKPPPQPFELLKSKPITTTPTIKKGVTFSETPKISNSPPSPSSSSPSPPHNQPIIVNKPIPSKSAPPPVRTTSSPSIVTKKFVPTIPTQTTTASSSSTPTTPKNQHLSKDDSSIPPINTSQTNNNISNSSIPSPKSKSALSLSTPKDSITGKPIKPPSNSDLSISTTPLPPTSSSPTSSSPLQSPKISSPSVLTVSQKIALNEKIAANQAKKNPLSNSGGLKQISPDLIKSNNINK
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.
Subcellular Localization:
Nucleus.
Sequence:
MDYNRMSSFLEYPLCNRGPSAYSAPTSFPPCSAPAVDSYAGESRYGGGLPSSALQQNSGYPVQQPPSSLGVSFPSPAPSGYAPAACNPSYGPSQYYSVGQSEGDGSYFHPSSYGAQLGGLPDSYGAGGVGSGPYPPPQPPYGTEQTATFASAYDLLSEDKESPCSSEPSTLTPRTFDWMKVKRNPPKTAKVSELGLGAPGGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREGGRMPAGPPGCPKEAAGDASDQSACTSPEASPSSITS
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFWEPQDLCELALPLLKIWKYTGLLHYELHGKINSPDRRFVFKSSYFTLLIACLILGNLVVYMYYFDVTKDLKSCIVFIQMISNTVQNLGMIYTSHQKKSEFGVLFSRLLKMEKLISRKFGNKFLYNDILKYFLRVVLPKYSVVILVFVLNALYLFGANCEDLIYGACFYVGWIFDLNSELLLTFFLITVHQLYKKFNTGVKNNTNLGLRDINRIHSTLHDVTIILKDVAQGFIFYKLIPDFTCSVVGLYYLFTNGVDNFLNTFEKFLDLVLSLLGIPSIIVSNLYLMYLFEKISQEANETLEIVHKNCYNQKAPKKIFYKDKEIFYLKTIIRPAEFSIFGLFDFNFPFFYSMIVAVTTYLVYLVQFRQMEHV
The following text describes a protein:
Function:
Putative pheromone receptor implicated in the regulation of social as well as reproductive behavior.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTLDSHCRQVFVALTSQSKRRVSRGLSICSTCVISTFQVITITPSTSKWAWLKPRLSTWIFSSLLCSWLINLLIYGYMLDMVIAKTNNTLVGHGYTDGYCVNKQVGNHNSGSFLSIVIIHDLFFVTIMMCASLYMVLFLYRYRKGAQHLRSPNLSFQPSPERKATHSILSLVSCFVLIYWLNNCVTLYSFYSSERIPRVESINAILTTCYPTICPFLFMKNNKVILQFISSFSIQRMTCFQSSIHG
The following text describes a protein:
Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Sequence:
MDLVTKQAQNNRKIPEAIFFENIDELISKNSIQRLMESLQEAYNKYKFMEAQLVKQRESMQNKLPEIERALTIVEHLEHQKEDEVVDFLITDTIYSKAVLPKENKTVALWLGANVMVEFEFNEAKGLLSSNKENASSNLRQFDEDIVFLKDQITTIEVNIARVYNANIRIQQTQQQQQQQQQQVK
The following text describes a protein:
Function:
Member of the two-component regulatory system VxrB/VxrA involved in the regulation of diverses processes, including virulence, the type VI secretion system (T6SS) and biofilm formation. VxrB positively regulates the expression of the T6SS, a virulence nanomachine that directly translocates effectors into bacterial or host cells, thereby facilitating colonization by competing with sister cells and intestinal microbiota. In addition, it activates vpsL expression and biofilm formation, and represses motility. May regulate biofilm formation via its regulation of key biofilm regulators and cyclic di-GMP levels. Significantly contributes to both attack and defense via T6SS, while also influencing competition via regulation of biofilm matrix production. Is critical for colonization in the infant mouse model.
Subcellular Localization:
Cytoplasm.
Sequence:
MSNQWWDEWAEKCHSKAHRQLLFWRYLVKQTLLLVEDDKNLADGLLVSLEQAGYDCLHAETIADVKQHWDKADLVILDRQLPDGDSVQHLMDWKKIKDIPVILLTALVTVKDKVTGLDAGANDYLTKPFAEAELFARIRAQLRSPDSGQDDSKVVTSNLTIDKATREVFFNGESITLTRTEFDLLLFLASNLGRVFTRDELLDHVWGYNHFPTTRTVDTHVLQLRQKLPGLEIETLRGVGYKMKA