lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May play a role in the Notch signaling pathway.
Subcellular Localization:
Nucleus. Nucleus, nucleolus.
Sequence:
MAQECWNKINIPFPSAVSSTRIPFTGSIDLLIDCLLADCEKVLTLLCSEVLQTEIRVLYELLYILNNGFRQHKPFRALKQVEQCVNRLKEMKLQAAVEDLKEVCPNKFQREAGAEAGECDVPSQPMLEWLGLKLLGASSLLARTLERCTKTFLLTRQHLRLGEFIVLNVVITSMLSRLWVFFRGILRALIPMYRRNCELLQKVSQSQPMAYLTDFTLPEDLKDFLCLTYPDLKIEEVTKDLLKGTRGKRKSKFSLLSKLFGDTEQQEEIGEGERDLMPILSAGHYEVSSLDLGAAVSQRRTDYSDVSPYGLGIKAMLQQSSKTTKQKSLEQQMKLDSSSKASLCQKRTSLKKTSSFRNMAALLKELMNWCRSCKFYQEHKRLAFLSLKCGRMESLEAEGVRVEKRLKTFKIKVQKALTLQQTFPPKHSCSLPALLRTRWQNKFFMRHFRTLRRRSAVSRKSSGTVKGSLNQRRKCRPLLQSSNEVESGENVTASVEIEKMDSQTSLQEPNIPKDDIDDIFESFGF
The following text describes a protein:
Function:
Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.
Subcellular Localization:
Nucleus.
Sequence:
MADDRLTDERAEKRKCDDFGSLYLERTTVRPLGAAAESPDGAFKKPKPSEGAGLGRDAANTPPNPAIPPTPARRRHRTTFTQEQLAQLEEAFSKSHYPDIYVREELARATKLNEARIQVWFQNRRAKYRKQEKQLSKALSPVLPPMASCNNMMRGIYQPAAGHNSAVRPGSYQYQHMSNTINPASSCARYPQMQMASSAYAPPPMAQFSMPPTTNMGMRVEQHDDDWYNKSLTAALRMNPSHHPNLSAPVLQYQTSPERFLSTHRASLFA
The following text describes a protein:
Function:
Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
Sequence:
MQASQFSAQVLDWYDKYGRKTLPWQINKTPYKVWLSEVMLQQTQVTTVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGEFPQTFAEIAALPGVGRSTAGAILSLALGKHYPILDGNVKRVLARCYAVSGWPGKKEVENTLWTLSEQVTPARGVERFNQAMMDLGAMVCTRSKPKCTLCPLQNGCIAAAHESWSRYPGKKPKQTLPERTGYFLLLQHNQEIFLAQRPPSGLWGGLYCFPQFAREDELREWLAQRHVNADNLTQLNAFRHTFSHFHLDIVPMWLPVSSLDACMDEGSALWYNLAQPPSVGLAAPVERLLQQLRTGAPV
The following text describes a protein:
Function:
Possesses phosphatase activity toward para-nitrophenyl phosphate (pNPP) in vitro. Possesses phosphatase activity toward several phosphotyrosine-containing peptides in vitro, with low peptide substrate specificity.
Sequence:
MNNDTSKKLGTLVSDDGPVNVYVWDMDETLILLRSLLNGTYAESFNGSKDVKRGVEIGRMWEKHILKICDDFFFYEQVEECNEPFLDSLRQYDDGKDLSRYEFKQDDFSTPTDDLNKRKLAYRHRAVAERYEKGLCPFIDSESMSGLDELYNVTDEYTDRWLSSARAFLEQCSCVEESSDGTSAIEQSSQDIHILVTSGALIPSLVKCLLFRLDTFLRHENVYSSIDVGKLQCFKWIKERFNHPKFRFCAIGDGWEECAAAQALQWPFVKIDLQPDSSHRFPGLTPKTVSYYFAAVYGNSDADSSKE
The following text describes a protein:
Function:
Required for initiation of translation of the COX1 coding region. Also involved in the stability of the intron containing transcript of COX1.
Miscellaneous:
MISCELLANEOUS: Present with 1160 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MKRCAPAVLRNYNYKKGIWSTGVPDHIRKLLRDKSTSPLCSQDERNLVSYFMARGSVPLKSVGSGLTKKATTSITSNSATTTFERQYLIKYLYRHQAYGNVIKIAQKFLYTTIGSQRLLKQDASLPELKKFLLSLLILQRGIQLDQAISDIIQRFLLTQKTMVIDLINSIFSRMVIMNMHEEAVYKWVKWMKLVNGHCEFTNYMENKIVLRNFLSFMRQSNVRPDYLSYLKAIQLTQGPAIASQFATTLLFLLTYIRKFSSAEAVWNYKCEHNLPIVSSDLTCILKTYCHMQKFNLVSSTYWKYPDAQHDQNQFDYLLVAHSRLHNWDALQQQFNALFGIGKLPSIQHYGILMYTMARIGELDSVNKLYTQLLRRGMIPTYAVLQSLLYAHYKVGDFAACFSHFELFKKYDITPSTATHTIMLKVYRGLNDLDGAFRILKRLSEDPSVEITEGHFALLIQMCCKTTNHLIAQELFNLMTEHYNIQHTGKSISALMDVYIESNRPTEAIALFEKHSKNLSWRDGLISVYNKAIKAYIGLRNANKCEELFDKITTSKLAVNSEFYKMMIKFLVTLNEDCETALSIIDQLIKHSVIKVDATHFEIIMEAYDKEGYRDGIINLYKTMSQNKVPANSKILYYILKAVAKKSLQNNEEIKETINMVEDIMENAANGTLDVTYNKLHPSVMAWPMRMIVKHDSPQRALELYNRYNELFFKKHDWISNNNKFVMMRSLLVLLAQIEQWKDFETLFAKYMDRIENIENLPSSTTPNIKLRSIFSGLFPYKVSQLIAMNKIDELPLLWKKLREKGFILDNISWNSAVEALFKDPRTLSYGMKIVDDTLIHGYNLIHKFRLLTKLSEDKTQSSDKSWPTLKMKEKEPNKFQPRLYLKSDTYNSIMRQLDTYLDGIDDLKTLEDQVRDFISNYKYFMKDYLLMPRSKINKWEQIEMRHLSYFKELRKSKRVLPVSKF
The following text describes a protein:
Function:
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Domain:
Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
Sequence:
MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPHHAPPALATPSPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINIPK
The following text describes a protein:
Function:
Structural component of the gap junctions that specifically coordinates left-right asymmetry in the developing nervous system. Acts by forming gap junction network linking embryonic neurons and providing electrical coupling between cells, leading to promote or inhibit AWC signaling. Required for the left and right AWC olfactory neurons to establish asymmetric patterns of gene expression during embryogenesis. Acts autonomously.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Note=Specifically present at the transient gap junctions formed between the cell bodies of embryonic neurons. Excluded from axons and dendrites.
Sequence:
MWRTPASTGPLRQDRQMFFHATLARSFINALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYWIPMYENVPDDHTAREEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQTLINAACDGQALLDASDRQKAVEAITTNFVDNLDLQSPNGRIRARGWIARIKFSRFLSGQCLSILHSFTKLLYSMNVVAQFLILNACLKSSDFLFFGFQVLNDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLWQEFRERNWREFEEHEEMKDVEMRRIHGGERIVISNPGQTKSFL
The following text describes a protein:
Function:
May be involved in intracellular signaling through interaction with PtdInsPs and calmodulin (CaM); may keep PtdInsPs attached to the plasma membrane until Ca(2+)-CaM reaches a competitive concentration subsequent to an increase triggered by a stimulus, thus leading to PtdInsPs release and subsequent activation of InsPs-dependent signaling cascade. Interacts competitively at the N-terminus with calcium ions and CaM (in a calcium-dependent manner), and with the phosphatidylinositol phosphates PtdIns(3,4,5)P(3), PtdIns(3,4)P(2), PtdIns(4,5)P(2) and PtdIns(3,5)P(2). Also binds weakly to PtdIns(3)P, PtdIns(4)P and PtdIns(5)P. Negative regulator of hypocotyl cell elongation by destabilizing cortical microtubules in a calcium-dependent manner. Binds directly to and destabilized microtubules to enhance microtubule depolymerization when cytoplasmic calcium increases. In case of Turnip mosaic virus (TuMV) infection, confers sensitivity by promoting viral cell-to-cell movement through interaction with viral P3N-PIPO.
Subcellular Localization:
Cell membrane; Lipid-anchor. Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, plasmodesma. Note=Shuttles from plasma membrane to cytoplasm (e.g. colocalizes with cortical microtubules) upon calcium levels increase. Co-localizes with Turnip mosaic virus (TuMV) P3N-PIPO at the plasmodesmata.
Sequence:
MGYWNSKVVPKFKKLFEKNSAKKAAAAEATKTFDESKETINKEIEEKKTELQPKVVETYEATSAEVKALVRDPKVAGLKKNSAAVQKYLEELVKIEFPGSKAVSEASSSFGAGYVAGPVTFIFEKVSVFLPEEVKTKEIPVEEVKAEEPAKTEEPAKTEGTSGEKEEIVEETKKGETPETAVVEEKKPEVEEKKEEATPAPAVVETPVKEPETTTTAPVAEPPKP
The following text describes a protein:
Function:
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA (By similarity). Less toxic than abrin-a; The B chain is a galactose-specific lectin that facilitates the binding to the cell membrane that precedes endocytosis.
Miscellaneous:
MISCELLANEOUS: Induces cytokine production and proliferation of splenocytes and thymocytes in mice.
Domain:
The B chain is composed of two domains, each domain consists of 3 homologous subdomains (alpha, beta, gamma).
Sequence:
MKFETTKNKLHGNAYYQAQFQDPIKFTTGSATPASYNQFIDALRERLTGGLIYGIPVLRDPSTVEKPNQYVTVELSYSDTVSIQLGIDLTNAYVVAYRAGSESFFFRNAPASASTYLFTGTQQYSLPFDGNYDDLEKWAHQSRQRISLGLEALRQGIKFLRSGASDDEEIARTLIVIIQMVAEAARFRYVSKLVVISLSNRAAFQPDPSMLSLENTWEPLSRAVQHTVQDTFPQNVTLINVRQERVVVSSLSHPSVSALALMLFVCNPLNATQSPLLIRSVVEQSKICSSHYEPTVRIGGRDGLCVDVSDNAYNNGNPIILWKCKDQLEVNQLWTLKSDKTIRSKGKCLTTYGYAPGNYVMIYDCSSAVAEATYWDIWDNGTIINPKSGLVLSAESSSMGGTLTVQKNDYRMRQGWRTGNDTSPFVTSIAGFFKLCMEAHGNSMWLDVCDITKEEQQWAVYPDGSIRPVQNTNNCLTCEEHKQGATIVMMGCSNAWASQRWVFKSDGTIYNLYDDMVMDVKSSDPSLKQIILWPYTGNANQMWATLF
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
Sequence:
MRSQLSLIGKKEGMMHVFDKNGNLVACSVISVDANVVAQLKTASSDGYNAVQMGADVVQAPEKTIEKRFSKALLGHFKKSGGRVCRVLKEVVVSEEAVQSVSLGDEFGLEIFDGVSNVDICGISKGKGFQGVMKKFGFRGGPKSHGSGFHRHAGSTGMRSTPGRCFPGSKRPSHMGCDRVTVKNLEVVKVDLDRKVMLVKGAIPGFKGSVVVVKRSCGVEG
The following text describes a protein:
Function:
Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVGLSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDHVQKVPGIAAAAPYINFTGLVESGANLRAIQVKGVNPQQEQRLSALPSFVQGDAWRNFKAGEQQIIIGKGVADALKVKQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMGSSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAMVLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCGVIIGVVVSLQLTPIIEWIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSLLASWYPARRASNIDPARVLSGQ
The following text describes a protein:
Function:
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters.
Subcellular Localization:
Nucleus.
Sequence:
MTAKNVGLPSTNAKLRGFIDQNFSPSKGNISLVAFPVSSTNSPTKILPKTLGPINVNVGPQMIISTPQRIANSGSVLIGNPYTPAPAMVTQTHIAEAAGWVPSDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSAYDQENIRRRVYDALNVLMAMNIISSLPTGKKRNQVDCNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPAVNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKIARSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDPTTGATVPQSSVNQGLCLDAEVALATGQLPASNSHQSSSAASHFSESRGETPCSFNDEDEEDEEEDPSSPE
The following text describes a protein:
Function:
Activated phosphatidylinositol-specific phospholipase C enzymes catalyze the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) involved in G-protein coupled receptor signaling pathways. PLCB4 is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development.
Subcellular Localization:
Cell membrane.
Sequence:
MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKASDDLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKCSLQEYGIDLRTQSQLSLCLAMKQSKEMDQLKKVQLEHLEFLEKQNEQLASFGIHMPWPTVTSGEGDAADGEIGSRDGPQTSNSSMKLQNAN
The following text describes a protein:
Function:
Possible ligand of InR/insulin-like receptor.
Subcellular Localization:
Secreted.
Sequence:
MFSQHNGAAVHGLRLQSLLIAAMLTAAMAMVTPTGSGHQLLPPGNHKLCGPALSDAMDVVCPHGFNTLPRKRESLLGNSDDDEDTEQEVQDDSSMWQTLDGAGYSFSPLLTNLYGSEVLIKMRRHRRHLTGGVYDECCVKTCSYLELAIYCLPK
The following text describes a protein:
Function:
May play a role in the regulation of metabolism and signal transduction processes.
Sequence:
MGSSGCSSEIVESNEDLGNAPVSGSSVLHINVKTEEKDGRRRGHPVEDELDQLLKAIDSRTYRRALSPGQAGADSLLKHAQKTPRSGSSQIAVPGICSKPVNMKQALRRHCISQASEMAAMKRLSMSPGSSSSSEAGTIHRLYASLMVQSSDGSLVHDDKKNLIEISITPEKISKNLSRGTSGFSEDCDFETADGSAVTSIHSASSTSTDIQKVRIQDVISGDPVESESSIVQNGKTHKQVSAATDDSPSRIPILIKPITTSRLVKPVFRCKTSSKSKMKEEQPSLGNSSNSTKFCSSKESISHVSTSSSSASSISNPTSCAEGEINPGPEKSDERSSEWLTLERGECSQNSKSSISEYGCSTSISDESQFGLCGYNNRPHMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVHSDCLFALKVMDIEYLISRRKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDLSLRCSVSAVLLRSSSVAANHQPKKLTSPCAESYCINSSCLQPSCAQTSCFRPRPWVPKPRKPKSSLKGLPQLVVEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELVYGRTPFRGPGNDETLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSAAPPETRPCDVVTLATVRKKKEGKCLDFRSAEELEFEVF
The following text describes a protein:
Function:
Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine.
Sequence:
MTVITDITELIGNTPLLRLKNFDVPEGVAVYAKLEMMNPGGSIKDRLGDMLIRDALDSGKVKPGGVIIEATAGNTGIGLALSARKYGLKAIFCVPEHFSREKQQIMQALGASIIHTPRQDGMQGAIQKAIQLETEIENSYCVLQFKNRVNPSTYYKTLGPEMWEALDGNIHTFVAGAGSGGTFAGTASFLKEKNPAVKTVIVEPVGSILNGGEPHAHKTEGIGMEFIPDYMDKSHFDEIYTVTDENAFRLVKEAAEKEGLLIGSSSGAALYAALEEAKKASAGTNIVTVFPDSSDRYISKQIYEGGI
The following text describes a protein:
Function:
Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms.
Sequence:
MRGLILALSLALVAANQLSFTPEFSPGKTYEYKYEAHLLGGLPEEGLARAGVKIESRVWISPIAPDTFIMKLVEPALYEYSGIWPRETFRPASKLTTALAAQLLTPIKFEYTNGVVGKVFAPPGISTSVLNIYRGLLNILQLNIKKTQNVYELQEPGTQGVCKTHYVISEDSKADRIHLSKTKDLNHCQERIYKDVGLAGYTESCTECEASGKTMKGAAAINYVMKPSTTGSLLLEATATELIQYSPINILNGAAQMEAKQTLTFLEIKKIPVEPISADYLPRGSLKYEFGSELLQTPVELLRISNAEAQIVETLNKLVTLNMGKAHEDSPLKFIELIQLLRVARYESIEALWDQYKARSDYRTWLLSSIPAIGNHVALKFIKEKIISGDLTSFEAAEALLSSLHLVAADLESLKLVEGLAMTPKVKENPVLREISMLGFGSMVYKYCTEFPSCPVELVKPIHELIIRALERRDYDELISAVKVLGNAGHPGSLKPLMKLLPGFGSSANNLPHRVHVEAILALRRIAKREPKMIQDMAVQLFMNKELHSELRMVSAIVLFETKLPIGLVTTLAQSLLKESNLQIASFIYSYMKAITKTTSPDYSSVAAACNVAVRLLSPKFERLSYRFSRAFHYDAYYSPWMVGAAGSAFYINDAATVLPRTVMAKARTYLAGALVDVFEVGVRTEGIQEALLKVNDSPATDRITKMKEAIKALSDWKAYPSSQPLASAYVKVLGQEMAFANIDKPMVEHIVQLANAIDIRAYGKKALDALLAGYTKQYSKPMLVAEVRRIIPTSVGFPMELSLYSAAVAAASLEVQASVSPPLPENINFAHLLKSDISFKAAIAPSFSMHTYAVMGVNTVFLQASLVSRAKIHSIAPAKFAARLDMIKGNFNFQILPVEGVDTIASARLDMYAVARNVEDLEAAKVTSMIPAVNLTHLSKQNSTSLRSRMASSVEDSSSASSEILFSKTPNQVASKLKVPKAFMWKLCALSYTFGIKACAELESRNASFIRNSPIYTVIGNHSFALKVSPAPGPAIERIEIEVQVGDRATDKIIKVINMSEEDEILEDKNVLLKLKKILTPGLKNSTTSSSSSSSSSRRSRSSLSSATSSLSSSRTSSKTSSRSSSKTSSRSSSKTSSRTSSKTSSSSSSSSSSRRKSKTIDLAEVLNRTSKWQSSSSSSSRSSRPSRSSSSVRSSSSSSSSSSSSSMSRQELYEMNFTKHHIHQHSISAERVKSKSSAYSFESIYKKVRYLSNTVDSLVTILIHAKRADHKNQGYQATVYYDKDNSRVQIIFANLTENDNWRICADGVMLSKHKIMTRVTWGIDCKQYNASIIAETGLVGKEPAARLKMTWERLPEGLKRYAKWASEYLSRIAVRNGVSQAKVKNFQKQIQLTAAVNETNLNVTLKTPQSTLYKLGLGLPISLPLGETAAELEAYPESWPGKLSYMLTKAHAAQCILVNDSLITFNNKKYKNEMPHSCYQVLAQDCTSELKFMVLLKRDQTAEQNEINVKIENMDIDIYLRDNATVVKVNSVEILSANMPYQHSTGNIQIREKAEGVSLHAPNHGLQEVFFNHTTVKVQVADWMRGKTCGLCGKADGEVKEEYRTPNERVSKNATTFAHSWVLSGQSCRHTSECYMKLESVKLEKQVNHLGEDSKCYSVEPVLRCLPGCMPTRKTTVNVGYHCLPIGTNLNRNDGLNSIFEKSIDLRETAEAHLACRCTAQCA
The following text describes a protein:
Function:
Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).
Subcellular Localization:
Nucleus.
Sequence:
MGVREDDDYERDDEGEEEEEEAPERLDDDDEDEEEGQDEYEKDDFIIDGDEEEEEEPEEAEDDARQATDEEERVKKKKRKKREHNDQLDEDDYDLLEEASVRFKRPSQSENKKFKRLKKARTEGGAVGLSDEEEDEEGGRRGRTAEEALKYTLFGDDEGVAPEDVAEEEQGEDDLGEEDEMADFIVDEDETDENGQLVRTKRPKKKKYSRQAPGISSSALQEAQEIFGDVSQLLEDRRIRVSEAEREEGAHDEDDAGRGRLAKEFEPSVLEEKYMTENDDRIRETDIAERLQPMAEIILPLPQAEIAREAEWVYERAFGKFALPDQRPELQHVVNTDKVEVIKQIANVIQLLHEVEVPFIGMYRKEMCKDLIYEEQESIDADGDEARPTLRHYKVLWIVQYWDKKWLLLQRRKSALKDAYVKRAGDQNAEFLSRILESLMDAPSEQCVDDIDAKFNLYCPPDEVEKHEFDDATSTPDEIAATRLAGEFSDIQSVLRGARHMAAVEISAEPAAREYIRNFYMDRAVVTTKPTVEGNRVIDPFHQYADVKWLLNKPVKAFEDGQWLLIQKAEEEKLLEVSIGIPKDATATLFQEFEPLYLSDGVSITAQLWNEQRKQILRDAVSTFLLPSMERETRVVLTGRAKQWVATNCADQLWKWISVAPYPRPGEQDDRDEEGARVLACCWGPGKPATAFVMLDSAGEIIDTLHAGYLTVRTGSYEQQQRKKNDQQRLLQFMTEHQPHVVVLGAANMSCRFLKDDIFEQVIFKIVEEHPRDLADGIDMIPLVYGDETIPRLYEYSRVSEEQLQQQPGIVRRAVALGRYLQNPLAVVSSLCGPSREILSLKLHPLQNFLTPDELYEAVERVMVTVTNQVGVDVNMAASHDWLFAPLQFVAGLGPRKAAYIKRAIQGAGRVSSRKEMLTSLELMKRNVFINAAGFIRIRGSGQVPSGTLDPLEDTRIHPESYDLAKKMAEDAYCEEHGETADEEALELAVEHVRDHPRVLRNLVIEEYAKVVQERGVSGKKLETLMDIKRELQHGYQDWRVKYMSPEPDEVFYMLSQESEETLCEGRIIQATVRKVQQNKVMVVLESGLIGFIRREDLSDDRDVDPADKVAEGSILTCRIKEDEEEKARKKVEEQKHKTFKARMIVHPQFRNISLLEATQSLADKEIGDGIIRPSSKGPSHLSMTLKFYPNVFTHIEIVEGGKDVSSMTSLLRLGKTLKIGEDTFEDLDEVIARYVDPLVGHWREMFRYRKFKQGTKEEVDNILRAEKEANPARIPYYFSVCYEHPGVFTLSYLKSINVHHEYVSVSPKGFRFRHRYLDTPDKLVAYFQKHINDPVPEAPPRRAAAAMVPSGDPRKAGSRGWTDNRGGGSSRGGWDNSQGGGGGGGGYGRSGGGWDQDRRGGWDRDRDKGAAAAAAVPAGGDHWSSWSKGGNWGAQQQQPQHHDNGWGQQQQQQQTDDGWGGSSGGGGGW
The following text describes a protein:
Function:
Minor myo-inositol uptake transporter.
Miscellaneous:
MISCELLANEOUS: The growth-defect caused by the iolF inactivation was only observed in the iolT-null background.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGNTNGDSAFNKRTIAAALANYIDAGSIVAGSAGLSLWVSYLKLSDTQIGLLGALSANAISAAVGALLGGFLADKVGRKAVYTNSMLVYALGICLVLFGVNFPMLLSGYIIIGLSVGADITASWTIIAENAPKKNRARHCGVAQVAWAAGAVVVLLLSVLAGDLGLLGNKIVFAHLLVIALITYILRIRLPESDAWQTKNQPEEAQAEKPAVLNKTSYFDLLKPMYLKSILFLMGVYLVWNLAAGVMGFFMPYIYQQVGGVSANMANLLQMGLFIFTGLGVALIFMPFADKYRKTVFGIAAFMAVIGWTLFLLPVEGLPILLLFIVVIGINNGAGQQANYQLWASEIFPTQYRASAQGLMFFLVRISIGIWSLFVPMIITNFGIGTMAAILLGCVTASMIIGLLFAPNTSGKSLEQIQEELYGSPQSQVKKGTESKIM
The following text describes a protein:
Function:
Probable electron transfer protein for hydrogenase 3.
Sequence:
MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEKESAPQLCHHCEDAPCAVVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGSRPLDIPANANTPKAPPAPPAPARVSTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCPTKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds directly to 7SL RNA. Mediates binding of SRP54 to the SRP complex.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MAVYLSDDPASKDRWVTVYPAYLNSRRTVCQGRRVPKAKAVDNPTVSEIRDICTSQNLSCELENNKFYPKESAKDVVCKGRVRIQLKNSDGTPVNADIPNRKALFCFLGEMIPKLKTRQTKTGQSDGNSSQQQAAASKKKKGKKAKGK
The following text describes a protein:
Function:
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Sequence:
MMFDMCNLTYDIYSSTGDTMSVIYSEVAADEPTTNSFWMPNHYQSTVKRLDDGYRVCDQIVACFQERAKIERSYALMMEEWTRKWRPLVDASSAYGSLLRAWQAFLGASERLSRLHMEMQRALVSEECGRIRAWQHDSYHRKLFGGFKESCDLESGFQRAQKPWTKKLKKVEKTKSLYHKACRKENIATIRESGLQAAAGSEATLDRKRTLREEHQRCSQETNKLRERYEKALQELDRCSPRYMEEMESVFEQGQSLEQRRIVFLKGAFLSLHRRLDVTADTSIQAVYSDLHQAIEDINDQDDLKWWRNRHGPGMPMNWPQFESWNPDQERPQVKIKKPKEPEKATLRSITPSQSSAKPAPAPVSGQRVRAVYDYVGQEADELSFKAGELLSKLEDEDEQGWCKGVTDSGRVGLYPANYVEPIQA
The following text describes a protein:
Function:
May act as a component of a corepressor complex that represses transcription.
Subcellular Localization:
Nucleus.
Sequence:
MRVGAEYQARIPDFEPGATKYTDKDNGGMLVWSPYHNIPDAKLDEYIAIAKEKHGYNVEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRNNQGDSDDDVEEPHPMDGNDSDYDPKKEAKKEVTDNLMGNNEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVIAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGAKHSDHSVFRPFTSSTGICSSSHRSHSNFKSATPVTASSTSCCSCSPPSASAAPTTGAIYSAKANPKSASPTAHPPS
The following text describes a protein:
Function:
Putative organic anion antiporter with apparent broad substrate specificity. Recognizes various substrates including thyroid hormone L-thyroxine, prostanoids such as prostaglandin E1 and E2, bile acids such as taurocholate, glycolate and glycochenodeoxycholate and peptide hormones such as L-arginine vasopressin, likely operating in a tissue-specific manner (By similarity). The transport mechanism, its electrogenicity and potential tissue-specific counterions remain to be elucidated (Probable).
Subcellular Localization:
Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Basal cell membrane; Multi-pass membrane protein.
Sequence:
MQAKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDQGPDPDLICRSRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSVLMFGFPQSLPPHSDPALESEQAMLPEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSSTPGSALDPYSSCNKNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTGCACLMTIPPENATVIPGKCPSPGCQEAFLTFLCVMCVCSMIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACALYDNVAYRYLYVSIAIALKSFAFLLYTTTWQCLRKNYKRYIKNHEGGLSTSEFFASTLTLDNLGRDPVPANQTHRTKFIYNLEDHEWCENMESVL