lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Pectin methylesterase (PME) inhibitor that inhibits PME in vitro.
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MAQRASRRPAAAAAAVVVAVVLAVSGGVGATPETACRAAAEEDRRVDYEFCVSRLSHHHDSPDADTWGLAKVAADVGVCIAGDAAYDAKAKLQAAKAGGEREALERCAELYDRMGSAFAAAYDDINRREYAAGKEKAGEAASLARRCDGAFADAGVAPSPLERQTAESVKIAIVCTAITNLVK
The following text describes a protein:
Function:
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
Sequence:
MQKTSMLTKEEAIKNRKWYLVDASGLVLGKLAVKAANLIRGKNKANFTPNQDCGDHLIIINSDQVVLTGNKKDNEFWYHHSQYMGGIKKTSGRDMINKNSDKLVFNAVKGMLPDNRLSRRLITKVHVFKNDKHNMEAQKPTLLNWS
The following text describes a protein:
Function:
Redox protein involved in a high-potential metal respiratory pathway. Is required only for electron transfer to terminal extracellular electron acceptors with redox potentials higher than -0.1 V. ImcH likely transfers electrons from the quinone pool to a periplasmic acceptor.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTLRKTAGYLWNPISLIGFLLAVVATGLIIAFIAMEMITGIDHPYIGLLVYFAFPGMLILGLILVPIGAWRVRNQRRTEVPEEVPPYPRVDFNDPHKRRLFIFFVLASVIFVLIVSVASILGFEFTESTTFCGELCHVVMEPEHKAWQGSPHARVKCVECHVGPGAEWYVKAKLSGLRQVWAVLTHSYHFPIATPIENLRPARDTCEQCHWPEKFYSGRQRVFYHYAPNKENTPREINMLIKIGGTPKSPHAMGIHWHIGTEVTYIARDRKRLDIPYVAVKQKDGSIVEYMDTEKPLTREEIAKAEKRRMDCIDCHNRPTHIYRSPAREMDEHIVSGQIDAGLPYIKKVAVEILEQPYKSKEEAHAAIEAKLPEYYAKNFPEVAKVKAAAINQAVAHVKDIYSRNFFPRMKVTWSTYPNHIGHFYTPGCFRCHDGKHKTSTGKIISKDCNMCHEMIGQKGENIPEGKVVKEFVHPADIGDALYNVNCSDCHMAAAEDSAGGEGPGKH
The following text describes a protein:
Function:
May be involved in neurite outgrowth.
Sequence:
MESPSIRLPSEQIASSRRRFDHLVDVQSAWATPAASNTTGSSTMAETRPITRASSDWMITLLKTSSQRQPVFKDFSGEFRVISRFNSDGHFLNVDRNLSYVDLLSSAMKTLDVKAASMNMTKIKNGSPPRGKCEPSLSSERTEESRTLHMIEKGVECNIADFILPMARNEKATSTGSLHKISSMSPQRSLPKACACQPSLRDDCSKRETAAPYQNTSGTKTPVGISNISIRHDTAVGIDLTDGSFHSKTAETVDEGILGSDGNDTHARRKDEEVPSLVKMKEFRNRRQTSDVSEYDKAYESLLGRQPAQSKERHISHGEAEKQDSGPSRGSIHSFRTRLSTDVSCDLEDPFDLSSAQSPTMKEIREDTDRKFERWIKKTSKRDSSKSGKSSRNTSASSGKSASSRHASASSTAGTLPDERCEIVKGSLVKTVSEGVPRLKSVKREEDMLLTGHHEKVQDLIEKAMTSSSSTIKDKSKVSPVNKSSSVGDMEDSESKISHLFPKVVVGQNLEVPKESQDPRRKSIVEDVVFDETGMTWGIYGAELDAETLGDAIQKHLELRIKQLQDQSKERAMSIDIERRQSRSERPTRWFCPLCPFLCLKSKET
The following text describes a protein:
Function:
Extracellular metalloprotease that contributes to pathogenicity.
Sequence:
MRVSVTFLVLLAGVLACNGNDYQGHKLYRVVPRDQAQVDFLDDLLKTDGELDFWAFPVAPMKNVDIHVSPDKRQAFEELLEASDMEFKIVVQDFSSMLAQEKVSARSGGFDSDYHSLSEIHAEILALAKAYSSVASNFSLGKSYENRDQLAIKILETGDSDSDVTDMLDNYEWVILPVLNVDGYEYTRTKDRMWRKTRTPGTKCVGVDPNRNFNYRFGVTGTSNNECSQIYRGKQAFSEKVTYNVAKFLYENRHRLKGYIDFHAYSQMFLSPWGYTDAKPSNYTEHMKAMTAAVNALQAVHGTRYVFGPASTTIYPTAGDTTDWTYGVLGCVHSYCVELRPTGNPPGFILPPAQIIPTGQETFAALKALVRNM
The following text describes a protein:
Function:
Transcription regulator that actives the transcription of genes required for nitrogen assimilation such as nrgAB (ammonium transport), nasABCDEF (nitrate/nitrite assimilation), ureABC (urea degradation) and gabP (GABA transport), during nitrogen limitation. Also represses glnRA and gltAB in the absence of ammonium. On the contrary of the MerR members, which require longer DNA sites for high-affinity binding, TnrA requires a DNA sequence of 17 nucleotides as minimal binding site.
Miscellaneous:
MISCELLANEOUS: The amino acid sequences of the N-terminal DNA binding domains of TnrA and GlnR are highly similar, and both proteins bind to DNA sequences with a common consensus sequence. In contrast, the C-terminal signal transduction domains of TnrA and GlnR have no homology.
Subcellular Localization:
Cell membrane. Note=Under poor nitrogen source such as nitrate, TnrA is associated with the cell membrane via the ammonium uptake proteins AmtB and its cognate regulator GlnK. Without usable nitrogen source, TnrA is released from the membrane to the cytoplasm where it is degraded by proteolysis. The presence of 4 mM ATP leads to concomitant solubilization of GlnK and TnrA. GlnK and Amtb are required for the membrane association of TnrA.
Sequence:
MTTEDHSYKDKKVISIGIVSELTGLSVRQIRYYEERKLIYPQRSSRGTRKYSFADVERLMDIANKREDGVQTAEILKDMRKKEQMLKNDPQVRKKMLEGQLNAHFRYKNR
The following text describes a protein:
Function:
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate and participates in the first step of the non-oxidative branch of the pentose phosphate pathway.
Sequence:
MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNSWDLPGSHVRLPGRAQSGTRGGAGNTSTSCGDSNSICPAPSTMSKAEEAKKLAGRAAVENHVRNNQVLGIGSGSTIVHAVQRIAERVKQENLNLVCIPTSFQARQLILQYGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDSKNLGDQWHKGIPIEVIPMAYVPVSRAVSQKFGGVVELRMAVNKAGPVVTDNGNFILDWKFDRVHKWSEVNTAIKMIPGVVDTGLFINMAERVYFGMQDGSVNMREKPFC
The following text describes a protein:
Function:
Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4 with high specificity. Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus outer membrane; Multi-pass membrane protein.
Sequence:
MKLRNLQRWQICLSFFTHFVISAFRSLLLGILADKIMAYFAMQVIYARRKCKISPPLTTGPQEFERIFRAQANCSEYFPIFLSLLWVSGVFSNQALAAFCGLIYLYARYQYFVGYAHSAQER
The following text describes a protein:
Function:
Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism.
Subcellular Localization:
Cytoplasm.
Sequence:
VAMNGRARKEAIQATARELIKFVNRSPSPFHVVAECRSRLLQAGFRELKETEGWDILPENKYFLTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRKSRRSQVGYHQVGVETYGGGIWSTWFDRDLTLAGRVIIKCPTSGRLEQRFVHIERPILRIPHLAIHLQRNVNENFGPNTEMHLVPILATAVQEELEKGTPEPGPLSATDERHHSVLMSLLCTHLGLSPDNIMEMELCLADTQPATLGGAYEEFIFAPRLDNLHSCFCALQALIDSCASPASLAREPHVRMVTLYDNEEVGSESAQGAQSLLTELILRRISASPQRLTAFEEAIPKSFMISADMAHAVHPNYSDKHEENHRPLFHKGPVIKVNSKQRYASNAVSESLIREVAGQVGVPLQDLMVRNDSPCGTTIGPILASRLGLRVLDLGSPQLAMHSIRETACTTGVLQTLTLFKGFFELFPSVSRNLLVD
The following text describes a protein:
Function:
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side.
Sequence:
MDSAAAGMRDSALDLLAALLTGRAPPAAADGDQNRRLLALLATSLAVLVGCGVALLFRRSSSGAAPLAHKSAAAKPLAAKKDQEPDPDDGRQRVALFFGTQTGTAEGFAKALAEEAKARYDKAVFKVLDLDDYAAEDEEYEEKLKKENIAFFFLATYGDGEPTDNAARFYKWFSEGNERGEWLSNLKFGVFALGNRQYEHFNKVGKEVDQLLAEQGGKRIVPVGLGDDDQCIEDDFNAWKELLWPELDKLLRVEDNSSTAQSPYTAAIPQYRVVLTKPEDATHINKSFSLSNGHVVYDSQHPCRANVAVRRELHTPASDRSCIHLEFDIAGTSLTYETGDHVGVYAENSIETVEEAEKLLDYSPDTYFSIYADQEDGTPLFGGSLPPPFPSPCTVRVALARYADLLNSPKKSVLLALAAHASDPKEAERLRHLASPAGKKEYSQWIIASQRSLLEVISEFPSAKPPLGVFFAAIAPRLQPRYYSISSSPRMAPTRIHVTCSLVHGQTPTGRIHKGVCSTWMKNSTPLEESQECSWAPIFVRQSNFKLPADPTVPIIMVGPGTGLAPFRGFLQERLALKETGVELGRAILFFGCRNRQMDFIYEDELNNFAESGALSELVVAFSREGPTKEYVQHKMAEKAAELWSIVSQGGYVYVCGDAKGMARDVHRALHTIVQEQGSLDSSKAEGYVKNLQMEGRYLRDVW
The following text describes a protein:
Function:
Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.
Subcellular Localization:
Nucleus.
Sequence:
MRCLLVSQDKRHDPIVLPDAITVILGRGPESRVTDKKCSRTQVELLANYAYRSVRVTQRGVNPTSVEEIHLRCGDSTTLQEGETLFLVNRLYPYHVRFEQDPSSPKKNLLHFFSPKRPLKEEEEVEEKDRKAQTAKRIKSSSPSEDEEEDEDDPHVTEKLRQLQETAALAEETHPSPQKQPAYQMAPQPRDSWEDHGKLLVFTKKGVVPSSKVAGFDLDGTLITTQSGKVFPTSPDDWRILYPEVPRKLKQLQSEGYKLVIFTNQMGISRGRLRPEVFKSKAEAVIERLGVPLQVFVATGAGIYRKPVLGMWDHLCEKANGGLAISLQQSVYVGDAAGRPANWAPGHKKKDFSCSDRLFALNVGLPFYTPEEYFLGWKKAPFVLPNFDPRTLDPKARLYDPPEACLTSSSSELVVAVGFPAAGKSTFLKKHLVSVGYVHSNRDTLGSWQKCVAMCQASLQAGKRVVVDNTNPDLESRQRFIECAKEAGVPCRCFLFTASLEQAKHNNRFREMTEKGHVPVNDIVLNTYKSKYVEPSLEEGFSEILKIHFVPQFADSQKESLYRLFSEG
The following text describes a protein:
Function:
Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MAAPGSLGGPVLKDVVAYVEVWSANGTENYSKTFRNQLVDMGAKVSKTFNKQVTHVVFKDGYQSTWEKAQKRGVKLVSVLWVDKCRVAGVHIDESLFPAANTNQHLPSLLKKKRKCMQPKDFIPRTPENDKRLQRKFEKMAKELQQQKTTLGTNVPVLSFESNGSLVYSPTGKVCRGHHSAMKKRLQEMKEKRENLSPTSSQMIEQSDDNTVNLLHEASLNLSHDTLCSDNSLAGGLPVSADDLCGGSASGTQEGKLFEFITERGSDVCAASPVLQTGSVGPSAAPCPLDLLTPHRSTSSPPKAETPQQSRAARGVVTPISKPSKPVAQGSSDGKKRLSPVSSATKGRPGGREQHMGSSAKRKKTPENSCPGLEERRKRRRSLGQRPAPRLRLWKAERGLRSVRRPAVKSLALEEFSYDDYFSPDNLKERVSEGLLGEQLPSRPPALHCQRSLSKTERTSLLDRADLSLIGRSPRPAVSTCSTAKPALSGADAGLGGGTSGGTSAADRTPGPCPRAEAQGGGDVRPAGGDAPQTRSQLIPQTGPQGDRSPLKGSREETEEWTDPQSTQKEGAPPETTESAAVHSEGKPSAAGGYAEDRPAGARGAPAHGSSGSVKSGPTRHSVVASSRKGCQDLLRLREESGKKGRGQEPTRTLVMTSMPSEKYSVVIQVVNRLKGFSLAQEVCGSTTHVLAGKPRRTLSVLLGIARGCWILSFEWVLWSLEMGHWISEEPFELSNYFPAAPLCRQERLSSAGQYRGTLFADQPTMFISPASNPPRAKLGELVVLCGGRVTQVPRQASIFIGPSPGRKKETVKYLSETWILDSISQHKVCASENHLLP
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Sequence:
MSSSKSKPTSSNNKLKQSTLGGFFQKSAAPVKSSKPLSSDSRVNDLSSDPDTKHPTTESNNDNEEEEDDGGVVERSRAAARGKRKSIVVAGSSSEDEVTSASRSRVPASKKARYSCASSASGASTPKSFGDGFSSHASTAGPSEADDDEVDDEDEEDKPSSKPKSKASAAKSNKSSSSIAKSKFGQSATNPDKPKSEATGEAPWKQGPWAFLRDIKDADGNPMGSPEYDPRTLFISKKDWASMTPFEVQFWEIKRSKFAELYEGDALIGHQEFDLKITKRVKMSMVGVPETSVDFWIAKFLAKGYKVGKVDQCETALGAEMRNKGSLPTSKYAKPPPQQKGSGKEIVRRELRSVVTSGTIVDGNILTDDSATCLLAIKESTNSDLPVFGVIIMDAATAEFNLTHFEDSANRTHLETIMSRFKPKEILHEKSGLSPATLRVLRNTASSDCTWTALKSDEFLEPDECVCRLTELFQESGGQIPQVFQSFNNKLETMQALGGLLWYLKQLNLDKDLLTCKNVKEMDAFRCSRTMHLDGKTISDLELLQSDGSEESRLLKLLNRCVTSFGKRLFRHWLCSPLQDGDAIRARLDAVDFLMNNPSFEEKFSTLSGLPDLERLISRVHAGACTVPNFLKVLKAFEKIYSTIQELRQLIDETPAMLLKELMDALPDTDKLLQNLEDMFTLNDDRRELLPLEGKDESYDMALEEEREAEKALKAELKAAKKLLKTDDVVYKDIGIKDIYQIQVSAKVKAPSNWTKMSGTKDCARYYSPQSAQLVKKLKQAREKKSCALKDFHLKVFLAFDENYLIWLQVVKSVAQLDCVLSLAKASIGLGETTCRPKIVDSDEAMVKFVTLRHPCTVGRDDSDFISNDVSVGGDECRMILLTGPNMAGKSTLLRMTCVATILAQIGCYVPAESAVISPVDRICTRMGASDHIFAHASTFKVEMDDARKILKEATSKSLVILDELGRGTSTFDGHAIAFAVLHRLATHSNCLGFFATHYSALTEDFRAHANIATKYMLTNVDEVTREVVFLYKLSSGVSPRSYGPHVAKMAGIPSKIVQRAISISEKFEKETKDRTELSAKQSNHRLLNLVLQADTAFLINLVKNGGFNQPASVKENLNTIDRILLGIQKFQFHN
The following text describes a protein:
Function:
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAEITVTIDTDQQKQAISDSFAKLDPQYLVKNPVLFVVELGTIIGLVMTIAPGLFGATGSRVYYAVITVLLGFTVIFANYAEAYAELEGEAQADSLRALQTEAEGKLLQNDDVDIEDISEDDYEVVASTEIEQDAVVFVDEGDIIPRDGTVVEGSASVDESAITGESEPVIRQSGGDRTSVVGGTEVLSDRIKVEVTSEEGESFLDQMIGLVEDAQRQKTPNEIAMTILLSGLTLVFVVAVATMFFFGEYLASFVGGFAGLDVAELVALLVALMPTTIGALLAAIRVAGMTRVTRRNVIAKSGRAVEAAGDLDALILDKTGTITTGERVAQDFHPLGDADDADVVRASYQSSLYDETTEGRSIVKLAEKMNGKVQTDGGQSASEELDEPGDSVDAPRDVSVTLDAEGLSESNFVPFSAETRMSGIDLSDGTEIRKGAVDAVEEYATTVPGKLRQKSNAISESGGTPLAIAVDGQVVGIIELQDELKPGIADRIAEIQKMGVETIMATGDNQRTARWVADQVGIDEFHAEFDPEEKIELVEDIQDDGKLVGMTGDGTNDAPALAKADVGLAMNAGTNAAKEAGNMVDLDSNPSKIIEVVGIGKQLLMTRGSLTTFSVANDVAKYFVLLPAILAAAIPGLGAMDILNLSTPASAVTATLMYNAFIIPLLIPLALRGVDYKAQSGAQLLRKNLIVYGGGGLIAPFIFIKAIDMLFVALGVFQ
The following text describes a protein:
Function:
Vacuolar iron transporter involved in the transfer of iron ions from the cytosol to the vacuole for intracellular iron storage. Involved in detoxification of excess iron. The transport mechanism is not well defined and the role of protons is not clear.
Miscellaneous:
MISCELLANEOUS: Iron transport is insensitive to the proton pump inhibitor bafilomycin A1 or to the proton ionophore CCCP in a yeast heterologous expression system. Functions as a proton-driven antiport in a bacterial heterologous expression system.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Sequence:
MVSKKTIEARKAYYNEDVVLSKEAHDFYHNLDKHGENHNLDKDNLKTIIFGSLDGIITIFAIVSGCVGAKITPTQVIIIGIGNLFANAISMGFSEYTSSTAQRDFMLAEKKREEWEIENCPSEEKQEMIDIYMNKYKFDSEDARNLVEITFRNKNFFLEHMMSEELGLIVTNEDKNECLKKGIIMFLSFAVFGIIPLSAYVAYTVFFGYTDYTTSFLVVFISTLTTLFILGLFKSQFTNQKPITCALYMVLNGMIAGMVPFLLGVVLKNNISE
The following text describes a protein:
Function:
Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. Promotes exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay.
Subcellular Localization:
Nucleus speckle.
Sequence:
MKMSMAHMKQNSGQERRGLPQRSSFPEKEDQGRSPLDRDYREKCRRYTEIAATQRSPAHEEPPTKRKKEDVDPLLIHTGGAYIPPAKLRMMQEQVTDKNSLAYQRLSWEALKKSINGLINKVNRSNIGIIIQDLLQENIVRGRGLLSRSILQAQNASPVFTHVYAALVAIINSKFPNIGELILKRLILNFRKGYRRNDKQLCLNATKFIAHLMNQEVAHEVLCLEMLTLLLERPTDDSVEIAIGLLKECGLKLTEVSPRGIHAVFERLRNILHGSEIDKRVQYMIEVMFAVRKDGFKNHPVIVEGLDLVEEEDQFTHMLPLEDDYDTEDALQVFKLDPNFMENEEKYITIKKEILNEGDSDSSTDQDATSSEDEEEEEEQVGDEEGQKVIVLDKTEINVVSFRRAIYLAIQSSLDFEECAHKLLKMEFPDSQMKELCNMILDCCAQERTYVKFFGLLAGRFCMLKKEYMASFEGIFKEQYDTIHRLATSQLRNVAKLFAHLLYTNSLPWSVLECITLSEETTTSSSRIFIKILFQELCEYMGLPQLNARLKDETLQPFFEGLLPQDNPRNTRFAINFFTSIGLGGLTDDLREHLRGGRVVCAQERPSSSLRCPETAVSNIEMIWKNSSNETLEISVAELSSTCKNEAIFMGWWN
The following text describes a protein:
Function:
Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.
Sequence:
MAMLLRSGRRLRAVRTALWLDQRASFFSFPSASQALVKSHTETRVVPFSCSEMFAVVADVAHYSEFLPFCVESRVLRSPNDNVMEAALRIGFNIFTESYTSRVLMIRPNKIATKAIDSPTFKRIESEWVFKPCSTPGSCEINFKVTFEVSSFLHANAIQLFFDDVALTQLNAFIGRARKMYGTTPRTMSQTPAAGLVTSGFSAQDARNESSDRKTAPAISSTASTQSSEDDSARREAKARASRRIKGGISAQNYSDLAAVFTDYADKDSKLYYGGFTAACMALSDEYVDLKDVSDSAALAGAVFSSFETHSTPKDWLTLDEFVVGVYLMTKGTFEQKAHNLFEVVNKTGDGKITREELTHAMQRRIRAVKKLFPKLLRDQVQIQMANEQVEELSSVQDAAMANSVQAIEKLMEEVEKEIPLAVNQIFREADLDQDDYIREQEWLFAWQAHPEFVELLTIDGMKKMAQWASVVQEANNSDDDNDDDDKTGSSGQSLDTRLTYVD
The following text describes a protein:
Function:
Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MAVMEVACPGTPGSAVGQQKEFAKAKEKTQSPGKKQSCIFQLEAVEKSPVFCGKWEILNDVITKGTAKEGSEGGPPAISIIAQAECENSQEFSPTFSERIFIAGSQQYSQSESLDQIPNNVAHATEGKMARVCRKGKRHSKARKKRRKRRSKSLAQAGVALAKPLPRTPEQESCTIPVQEDESPLGNLYARNVSQFTKPLKGPGLGHLCFKKQDEGLRPVLPRPELHKLISPLQCLNHVWKLHHPQATGPLPHPTHPFPFSRMPHPFPFYPLEPWRPYTLNPAFLDKLAAVSGQRPLPGPPHLSKPAYRDSQKPLPGPHLESSCLSREALEKVPAEEYLVHALQGSVSSGQAHSLASLAKTWSSGSSKLQRFSPETEDNEGVLLTEKLKPVDYEYREEVHWMTHQPRVGRGSFGEVHRMKDKQTGFQCAVKKVRLEVFRAEELIACAGLSSPRIVPLYGAVREGPWVNIFMELLEGGSLGQLIKQKGCLPEDRALYYLGQALEGLEYLHTHRVLHGDVKADNVLLSSDGSRAALCDFGHALCLQPDGLGKSLLTGDYIPGTETHMAPEVVLGKPCDAKVDIWSSCCMMLHMLNGCHPWTQYFRGPLCLKIASEPPPVREIPPSCTPLTAQAIQEGLRKEPIHRASAMELRRKVGKALQEVGGLKSPWKGEYKEPRPPPQDQAPCPQTLHTLPRENPPAKANTDGAPERQPPLPPEPPEPNKAPALNLSKEESGTWEPLPLSSLDPAPAKGPSLPDRRATFPELELQQLEIELFLNSLSQPFSLEEQEQILSCLSIDSLSLSEDSEKNPSKASQSSRDTLSSGVHSWSSQAEARSSSCSMALARGRPTDIPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPATAFSLVTKDGQPVCYDMEVPDSGIDLQCTLAPDGSFAWAWRVKHGQLENRP
The following text describes a protein:
Function:
Transcription factor that prevents axillary bud outgrowth. May also delay early axillary bud development. Probably involved in the auxin-induced control of apical dominance.
Subcellular Localization:
Nucleus.
Sequence:
MFPSLDTNGYDLFDPFIPHQTTMFPSFITHIQSPNSHHHYSSPSFPFSSDFLESFDESFLINQFLLQQQDVAANVVESPWKFCKKLELKKKNEKCVDGSTSQEVQWRRTVKKRDRHSKICTAQGPRDRRMRLSLQIARKFFDLQDMLGFDKASKTIEWLFSKSKTSIKQLKERVAASEGGGKDEHLQVDEKEKDETLKLRVSKRRTKTMESSFKTKESRERARKRARERTMAKMKMRLFETSETISDPHQETREIKITNGVQLLEKENKEQEWSNTNDVHMVEYQMDSVSIIEKFLGLTSDSSSSSIFGDSEECYTSLSSVRGMSTPREHNTTSIATVDEEKSPISSFSLYDYLCY
The following text describes a protein:
Function:
Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity.
Subcellular Localization:
Nucleus.
Sequence:
MAEKRDWGKVAQVSMKEVGDGLHDQMNCMMGALQELKLLQVQTALERLEISGGDGLGPAPSFLQGPRTPPEPCRWAGSRGSARPRASSPCGPPGCGSATSLSSQEILPGRNLVPPPRTWESESQGFIQQRVERAEPDDWTSTLMSRGRNRQPLVLGDNVFADLVGNWLDLPELEKKGGEKGEASGAGGVPGPGSRPRDPGRRFTLTANIFRKFLRSVRPDRDRLLKEKPGWMTPTASEPSTGRSKKVKKRGLSKGAGYFPFHTTGGTGQGERPSSSCPKALEPPASGFDINTAVWV
The following text describes a protein:
Function:
Vacuole membrane protein that recruits ATG8 to facilitate the degradation of vacuolar integral membrane proteins during early-stationary vacuole turnover (EVT) when cells enter stationary phase.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MENKLLCWWLYWPCVYSSIIATIISFYTITRHLLNYRKPYEQRLSIRILLLVPIFSVSCASGIIKPEAAQFYVDPIREFYEAFVIYTFFTFLTLLLGGERNIITVLSLNHAPTRHPIPLIGKICKPIDLSDPFDFLFVKKGILQYVWFKPFYCFGTLICSAWKLPKFEIFLNVFYNISVTWSLYSLALFWKCLYPELTPYKPWLKFLCVKLIIFASYWQSIIIQGLVVTGKLGTGNQDRTSGYVYKNGLLCIEMVPFAILHAVAFPWNKYTAFSIPYGARMKFIYALKDFLGCGDLIWDFKQTLFAGPLYYNYRNFDPEAMDLLSTRQQSGATMERLKHGLRFTDNGRNSYWVAYGSIDNNLVPESIEESWEDDIAGQRTFPEDPNYPVVHDYTMGHRYSRSMNDLRRDVQSRSSMAC
The following text describes a protein:
Function:
Removes the formyl group from the N-terminal Met of newly synthesized proteins.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MISQAKSLGAFQWSVPPLDQNLGKASSSCAQQKVLQAATQHSRRLTRYLYYIEKQTFVRASSSEGSASRQPASIESTKKQGWRLPISIDFLKGGLMEEKKGDKNLPPIVQAGDPVLHEPAQAVESSEIGTPELERIIDQMVDVMRAAPGVGLAAPQIGINKQIIVLEDKPEYMTRVDRDELQDQEREPFDLLVVINPKLSKKGRRTAIFLEGCLSVDGYRALVERHLEVEVTGLDRNGDELTVQARGWHARIFQHECDHLAGTLYVDKIVPRTFRTVANLRLPFASGVPRPGPVKDD
The following text describes a protein:
Function:
This is a 2S seed storage protein.
Subcellular Localization:
Vacuole, aleurone grain. Vacuole. Note=Cotyledonary membrane-bound vacuolar protein bodies.
Sequence:
MARLTSIIALFAVALLVADAYAYRTTITTVEVEENRQGREERCRQMSAREELRSCEQYLRQQSRDVLQMRGIENPWRREGGSFDECCRELKNVDEECRCDMLEEIAREEQRQARGQEGRQMLQKARNLPSMCGIRPQRCDF
The following text describes a protein:
Function:
TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauB domain of TFIIIC that binds boxB DNA promoter sites of tRNA and similar genes. Cooperates with TFC3 in DNA binding.
Miscellaneous:
MISCELLANEOUS: Present with 1130 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MAVIPAKKRGRPRKSVVAEVPYDSLASPVSENSGSKRPRRNASKKAVANFAQLVHAGRDDVINTTQVNNVDDTDDDDFVLNDEGDGEESDNVEIEFENELESTKNEVADLNSSGSGASVRPSGRRNTVQKLRLKKNSTKNMKSSSPGSSLGQKGRPIRLLKDLSSARDKIERIYGLNKEKLLLLAKVKEGFETSVFDFPFKNIQPDSPYFVCLDPPCKKESAYNKVIGDKNRTVYHEINKTEFENMIKLRTKRLKLLIGEVDAEVSTGDKIEFPVLANGKRRGFIYNVGGLVTDIAWLNIEENTDIGKDIQYLAVAVSQYMDEPLNEHLEMFDKEKHSSCIQIFKMNTSTLHCVKVQTIVHSFGEVWDLKWHEGCHAPHLVGCLSFVSQEGTINFLEIIDNATDVHVFKMCEKPSLTLSLADSLITTFDFLSPTTVVCGFKNGFVAEFDLTDPEVPSFYDQVHDSYILSVSTAYSDFEDTVVSTVAVDGYFYIFNPKDIATTKTTVSRFRGSNLVPVVYCPQIYSYIYSDGASSLRAVPSRAAFAVHPLVSRETTITAIGVSRLHPMVLAGSADGSLIITNAARRLLHGIKNSSATQKSLRLWKWDYSIKDDKYRIDSSYEVYPLTVNDVSKAKIDAHGINITCTKWNETSAGGKCYAFSNSAGLLTLEYLS
The following text describes a protein:
Function:
Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors). Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Promotes clustering of postsynaptic LHFPL4 (By similarity). Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of signaling by excitatory and inhibitory synapses and information processing. Required for normal signal amplitude from inhibitory synapses, but is not essential for normal signal frequency. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. Mediates cell-cell interactions between Langerhans beta cells and modulates insulin secretion (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane. Presynaptic cell membrane. Note=Detected at postsynaptic membranes in brain. Detected at dendritic spines in cultured neurons. Colocalizes with GPHN and ARHGEF9 at neuronal cell membranes (By similarity). Localized at presynaptic membranes in retina. Colocalizes with GABRG2 at inhibitory synapses in the retina (By similarity).
Sequence:
MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV
The following text describes a protein:
Function:
Required for maturation of 30S ribosomal subunits.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKITEQVEVIVKPIMEDLNFELVDVEYVKEGRDHFLRISIDKEGGVDLNDCTLASEKISEAMDANDPIPEMYYLDVASPGAERPIKKEQDFQNAITKPVFVSLYVPIEGEKEWLGILQEVNNETIVVQVKIKARTKDIEIPRDKIAKARHAVMI
The following text describes a protein:
Function:
Channel-forming protein essential for import of protein precursors into mitochondria.
Subcellular Localization:
Mitochondrion outer membrane; Multi-pass membrane protein.
Sequence:
MDYIQTLFTSVNQVGEKIDSYKSSLNLINPGTCENLSKEVSKDILLSNYAFTGVRADVTKGFCTSPWFTVSHAFALGSQVLPPYSFSTMFGGEPLFLRGSVDNDGAVQAMLNCTWNSNVLSKVQMQLSNGAVPNMCQIEHDHKGKDFSFSFKAMNPWYEEKLTGIYIISLLQSVTPKLSLGVEALWQKPSSSIGPEEATLSYMTRYNAADWIATAHLNGSQGDVTATFWRKLSPKVEAGVECQLSPVGLNHSAALMTGPKPEGLTSVGVKYEFAQSIYRGQVDSKGRVGVYLERRLAPAITLAFSSELDHPNRNAKVGLGLSLELPGSDEMIQQQQQQLAAQTA
The following text describes a protein:
Function:
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MIPVRCFSCGKVISNYWDEYKRRVTDGEGSAAVLDDLGITRYCCRRMFLSHVELVDVLSPYQ
The following text describes a protein:
Function:
Structural component of the gap junctions.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MNAPNGPSRKRAMPSKKITGPFNASIHEASPSKKLKTFEKKVQEFVEMKTLEELDKVKKRRDEEGQTTIEELCQKLTGHPDASGSYEDGLFIMNKPEWITEANIAKRKAELEEQLLQSVLLEIRYHPEFAAPFVDAIQAREEMKEEMAKSSRYTELWLEEIHRADKQIKVLGEKEEEARVEIETAAIPYYQWVPIVLALQSIAFYAPNWIWKTTSKITGLDVPRVVAEAHRLKNKPTERTDAIKELAGYLGDAVGVTGRGSTGRCSLAGSWFTVIYLLTKLFYILNLACQFFILNRFIGADCYDWAFNMLFHIVDGRKWSYISDATGLFPKVTLCDFLVRKVGNSVLYTVQCVLYVNALNEKIYFILWFWFLALLSVSLLNLISIICQIAFTRESSCKKSWLSGVASADERSIRRFAKFGLKHDGYLAVCFIKRHAGSQVAREIAQEMFGTFTRSQFGVYRRLPEKDAVLVEAEM