lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May play a role in the stabilization of the actin-rich cell cortex during cell division.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cleavage furrow. Note=Associated with the actin network at the onset of mitosis. Associated with spindle microtubules in metaphase.
Sequence:
MAATVYQRLHSVAVGVGSAAGSAIGSGSASLPGSGTGSGSGIGHAGNTSSSTSSALLSHSQLTRSLERILEEAHFSGELILTNRKLKDFPRTGTKYSLTDTVIADLSRNRFAELPEEVTTFAFLETLLLYHNTIRSIPESVKQLSSLTYLDLRSNQLSSLPREICFLPLQVLLVSNNRLTSLPDELGRLDQTLTDLDASYNQLANLPARLGELRSLRSLSLRSNHLLYLPRELTCLSLISLDVSNNKIASLPLEIRHMSTLVELQLENNPLTSPPASLCMRGLVHVFKFLETQATKDEKGSRSGGNYDGYTTLRRAPRHNSSGNVLEASTTGSTNNQRRHQVDSGYNTSDGLDKRWSHDAPTKSKTDSPLHCVSNSTAATLPRTLPSAVHSQADLMDASLTSSTSTIVDESLTLSPTASPCKLSYAHSNSSSNGSSPDQDDDIMLDHQERTVHHANGRSGKGLGNIQTYKEYKEALKQQRNQEISVYKQKHPNANHSPNDDEDLSPSPPSISNGSSSNTLPKSIMKQNSNQIGHNGNGNGSANGNGVDDVVIPKKPIQKVIPSRITEIKPASTSDIRSANSSDCLGYVKPQSPMKNGTSKFNTSNGGGVQTTVGIVSSTTIKSPVSSTTKLGTVKTHRSVTWNHDIPAEKLSFTMRREFDRQREETELMSQLRTIIETRLKMTLPVDIASALTDGVILCHLANYVRPRSVASIHVPSPGVNKLTMARCRRNVDNFLEACRRIGVDENLICCAADVLEGKGAVQVAITVGELFRLHGNGGCGSGNSSGAATPTKSPTRTTRATMSPTPLA
The following text describes a protein:
Function:
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity).
Miscellaneous:
MISCELLANEOUS: Present with 35900 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MDRPIDDIVKNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLKQLLSINKTELGPLIARLRSDRLISIHKQREYPPNSKSVERVYYYVKYPHAIDAIKWKVHQVVQRLKDDLDKNSEPNGYMCPICLTKYTQLEAVQLLNFDRTEFLCSLCDEPLVEDDSGKKNKEKQDKLNRLMDQIQPIIDSLKKIDDSRIEENTFEIALARLIPPQNQSHAAYTYNPKKGSTMFRPGDSAPLPNLMGTALGNDSSRRAGANSQATLHINITTASDEVAQRELQERQAEEKRKQNAVPEWHKQSTIGKTALGRLDNEEEFDPVVTASAMDSINPDNEPAQETSYQNNRTLTEQEMEERENEKTLNDYYAALAKKQAKLNKEEEEEEEEEEDEEEEEEEEMEDVMDDNDETARENALEDEFEDVTDTAGTAKTESNTSNDVKQESINDKTEDAVNATATASGPSANAKPNDGDDDDDDDDDEMDIEFEDV
The following text describes a protein:
Function:
Acts as a component of the outer kinetochore KNL1 complex that serves as a docking point for spindle assembly checkpoint components and mediates microtubule-kinetochore interactions. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and spindle microtubules. The outer kinetochore is made up of the ten-subunit KMN network, comprising the MIS12, NDC80 and KNL1 complexes, and auxiliary microtubule-associated components; together they connect the outer kinetochore with the inner kinetochore, bind microtubules, and mediate interactions with mitotic checkpoint proteins that delay anaphase until chromosomes are bioriented on the spindle. Binds the protein phosphatase 1 catalytic subunits gsp-1 and gsp-2, which has a role in delaying formation of load-bearing kinetochore-microtubule attachments. Required for the recruitment of spindle-assembly checkpoint components bub-1 and mdf-1/2 to unattached kinetochores. Binds microtubules which plays a role in silencing of the spindle assembly checkpoint, but not the formation of load-bearing microtubule-kinetochore attachments. Has a role in the correct localization of the spindly-like protein spdl-1 and the RZZ complex that is composed of rod-1, czw-1 and zwl-1 to kinetochores.
Subcellular Localization:
Cytoplasm, cell cortex. Chromosome, centromere, kinetochore. Note=Also found on the surface of chromosomes. Subcellular localization dependent on expression of hcp-3, hcp-4, knl-3 and knl-2. During anaphase of meiosis I, localized also to spindle-associated rod-shaped structures which depends on zwl-1.
Domain:
The N-terminus contains a number of repeats which contribute additively to bub-1 recruitment to unattached kinetochores. The repeats are not required for localization to kinetochores.
Sequence:
MDNQRKKRNSILKVRQETNLMDVLEDTTVATSSGATNRRVSFHQLKQVKNYDRAGGQIIDATPIKEKAYDTMSSDGNSTSHTTRLDMDITGLNSTPVTPKTQTPFNGSMDMSVENYDETARLFDITRDKTICVYEKTVETTTTKVVERVVRVPEGSSGANNDTLALFNMTDRAEVDMSVDGGSEGALKVDDTISVFNQTNVEPVDMDITVQKPLDDTMGVFRSPAIPTSSRIQKTSASTMDSQNMSMSMDMDITSNEMMAAFKSPKIMSSVLVAAVKDSDDMDLTGLVNTAAEDVADDTMAVFRTPTRAQTTIQKTSGEIPESVDMEMTGIGNSDAPDDTMAVFRTPTRAQQTVQKTSGEIPESVDMEMTLLALLQPVSDVKDNFDDVAMDITQQTLVGVSDDTMAVFKNPAAEKKTPGKPLFDESMEIESTIVCPDNVTFSETAQPENPAYHSSMLMSMASEVSEDVVVQKTSESLQQSSMRMSTTITEDVTASKNPESSTISEVQKIPEVVQKTSNGVEDIQNASETPEDVSMEITSEVVEGERGTMYQMSTMDVDSLQKTSLASPKIQMTSFTDTSEKMGGVSETSLIQTMMIEASESMECSEAPEDVTASPEGLTMAPEDVTVASNVSGIVSVSSISRRRRSQLQESLHRESPRRMALEKNLSMMSQMGGASEALAEFRQNKLKNQTTLLNDSVNTTIGANTSESIGRDIFKMNTSIRSPAHRSSTAPSPMVSKTLPESPKFHVTPFDAAIVNVIYLTPEDAETQEPIPEAFEFEKVLSAEESNVHKEIDTANWSISGAIKSNLDAEVMNIARGQAEMKFLELRGKFAKESNVEIAQKIQELESQNLELAGKIRDSQNLRVLQKQIEELQKPQFSLEEAERIENEYHETKVELLRAQAASIRRQHELLMTIREERRRLIHEIEEKDELLARLEEEDRKKKEEMVERVRGVMRA
The following text describes a protein:
Function:
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
Sequence:
MVYKIKKYGEDVLKQIAKEVELSEINDEFRQFLDDMVETMYETDGVGLAAPQIGVSKRIFVCDDGNGVLRKVINPIIVPLTEETQEFEEGCLSVPGIYKKVERPKRVLLKYLNEYGKEVEEIAENFLAVVVQHENDHLDGILFIEKISPMAKRLIAKKLANIKKETKRIKEENE
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.
Subcellular Localization:
Cytoplasm, nucleoid. Note=Localizes in tight foci to the chromosomal replication center at mid-cell; positioning does not rely on the C-terminus of SSB (ssbA).
Sequence:
MAISWKEMNELQPRVMKLLYNSIEKDRLSHAYLFEGKKGTGKLDAALLLAKSFFCLEGGAEPCESCRNCKRIESGNHPDLHLVQPDGLSIKKAQIQALQEEFSKTGLESHKKLYIISHADQMTANAANSLLKFLEEPNKDTMAVLITEQPQRLLDTIISRCQTLPFQPLQPKAIEDRLIEQDVSPHMARLLANMTNNVAEAVELSRNDEFAESRAKVIKLYEVLHQRKGHAFFFIQDQWMPFFKEKTHQEMGLDMLLLIYRDVLSIQIGNEDKLIYQDLFQSIKQHALQSTQQSVTNQILAVLEAKKRLHSNVNVQGLMEHLVLMLQEG
The following text describes a protein:
Function:
Structural component of the gap junctions.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MPRTPPPPPRRPMVFAEIVGTLSFLQPQADDDIFDRLHYYYTTTFLLLTAVLISLKMFGGRPIECWLPAEYKSSWEDYTEMYCWARNTYVTAFEDDNLPEVVNREYTMVSYYQWVPFFLVYVAFSFYAPCLLWRLFYDKSGIRLKDIMAFANDKANVVPAQRQANIRGLSAHLSSVFKHRFRIGEKHPYHHKVFKIFNVRYYESYLTYLYLGIKGMFLMNVLMQMYFMSRFLELDSHRYYGYGILYDLIMGRGWKESSNFPVVTYCDMQIRILGHVQRHTVQCVLVINIFTEKIFFILWLWYTLLSFISFGSILSWIFGSIPFNQRRQFVARRLELADVNFEKSRYKHELDEFVRDYIKIDGIFVLKMITIHSGILMCTDIVDQMWDQYLEESGNQVIREIIDEKSFGDDYDRSASAGGLSIDPGIRRKTSVLVPLMSREDLNVDQSPTTPTPQFLRPPSSRMTANV
The following text describes a protein:
Function:
Synthesizes sphingolipids through transfer of a phosphatidyl head group from a glycerophospholipid on to the primary hydroxyl of a ceramide in the lumen of the endoplasmic reticulum. Catalyzes the synthesis of ceramide phosphoethanolamines (CPEs) (such as N-acylsphing-4-enine 1-phosphoethanolamine) by transferring phosphoethanolamine head group, which is smaller and more hydrophilic than the phosphocholine (PC) headgroup transferred in the canonical sphingomyelin synthesis (SMS) reaction by SMS1 or SMS2, from a phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to a ceramide (such as N-acylsphing-4-enine). The larger PC prevents an efficient fit in the enzyme's catalytic pocket, leading to little or no SMS activity. In vitro, in the absence of ceramide, it has PLC activity with preference for phosphatidylinositol and phosphatidic acid, but also hydrolyzes phosphatidylethanolamine.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MQTSLDVEAGDSPIMLSADVTEWSTDDVRRWMVDKGFQEYTELLCDRHRLNGVALLSLTEEDLREPPISMHVLGDLKRLVDAITQLRHDTFTFRPNIPDGRSSSGDSSPTRSDSPRDISKTLETLVKINMSDAQEKPHFPSEKWKTFVAFVYLCGMMMLNPIFINIIHERVPDKSVEPPLPDVFFDYFDRVVWAFSVCEIAGMINSALLLIVWILHKHKWIVLRRYCLIVGTLYLLRCITMYVTTLPVPGMHFRCSPKIHGNLSAMFDRAMTMMFGLGLSITGSHHLCGDYLFSGHTVILTITYLFIKEYSPRGWFILHWCTWLVSCIGIFCILLAHDHYTIDVVVAYFITTRLFWIYHTLANHEVLKKPSPLHHLSRTWWFSMFRMAEGNIEGVLPREYAWPLPWPKRFHDTRFHYMGVCKRV
The following text describes a protein:
Function:
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. May act as a tumor suppressor.
Subcellular Localization:
Nucleus.
Sequence:
MQREETDTEASNSSDGGPGEAVQEQLETLCRELNLDQETGAETIRDFTRTWSTYSLEGEVKHWLACALYAACRKGVIPTVGKGIMEGNGVSLTRILRSAKLSLIQFFNKMKKWIDMSNLPQEFRERVERLERNFEVATVIFKKFEPIFREIFQNPHEEPPRLPRSRKQRRLQCSAKDLFSFCWTLFVYSKGNFCLIGDDLVNSYHLLLCCLDLIYAHVLQCPNKEDLLNPSFTAKLPALDPSSEDAPCIIRALCELYDGIFVEAKGIKEHYFKPYISKLYDKKILKGACLLDVSSFTDNNKSLNKEYEEYVLTKGDFDERVFLGVDAEEEIGSPRKFVVEFPMGICTPRKQMESNLQQHFERKRSFAPSTPLTGRGYLKEEPTVITPVSSATQCVSRLQSMVAGLRNAPSEQLIEVFKSCVRNPLENVLNIVRDIGRRFCHHYTQSTEDQPGSHIDFAVNRWKLAEILYFKVLETIVVQESKRLHGKDLTALLEQDIFHQSLIACCLEIVLFAYSSPRTFPWTIEVLNLSAFYFYKVIEVFIRSEDGLSRDMVKHLNTIEEQILESRAWTSDSVLWVHLDAVDNVPTCEEVIIPSNFETGNEAGVGHLPMMPASPIVHPRLKEVRTDLGGSFRRDCQPLSPISVHDRYSSPAAGSAKRRLFGDDCPREQTVDKITTPDITRIRIALSPSPDKTAQSIGQTIAIPVQGLANESVKSLFLPMKTSPPQSENYVPVPLTAQALISPLTKRQLGRMPESCPTSARKPKKTGSLALFFRKVYHLASVRLRDLCLKLDVSNDLRRKIWTLFVYSLVHCTDLMKDRHLDQLLLCAVYIMAKISKEERLFHDIMKCYRNQPQANSHVYRSVLLKRIPQASGDETSTSQDVEMTARNSSDSHPTPSGFTGSPCGNAERGDLITFYNNVYVERVRSFALKFASTQDHLMDAPPLSPFPSIKQQAISPRRVSQQHSIYVSPHKNSGSLTPHTALLYKFNGSPSKSLQDINSMLKQEQRSRKRIIAIDSDTDSPAKRLCQENDDALLKRLQDVVSERANH
The following text describes a protein:
Function:
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Subcellular Localization:
Nucleus.
Sequence:
MTMDGVFPLTATVDYCDIFLTHDSASVRKAHNTGWKHKMQVEHYYNAEVDPAKIQSVIDNVTKAYIDAGLPGFPELIAVGVNGQRGQPVGGPPRPPQPFHNGGRPGPPGRPPMGMFPPQRPMMPPPHMRPGLSQMPPGMRPPGPPPHGFMNGSMPPPLGTPVMENGPVAGQQSQAPVAPRIHPDRLRLAGNSIKSKLVIESIYCFYPFGCLDSQIATHTFLYHCANDS
The following text describes a protein:
Function:
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Sequence:
MLALRLARVVRPTGASIRHLTWSHPARLYSSVDKVNLPKAPSKEELKTPVPDELLEEVKVLENTPLEPVDPEKATIDLKTQFQAAREAELAAMTLPERFVYSLPKSMIPYARLMRMEKPVGTWLLFNPGVWSIGMAAYMSHAAVAPTLYTLSLFGIGAFIMRSAGCTINDILDRKLDAQVARTFDRPIAAGDVSVKQAVAFLGAQCAAGLGILMLLPMNCWWLGALSMPFVMTYPLFKRFTYYPQAILSLCFTWAALLGPPAMGVWCWPVMLSLWGSNFLWCMVYDTIYAHQDKVFDVEAGIKSTALAWGDNSKSIMTVLTLGQLGLLFGAGVYADMGPGFYSAFTWVSYRLGKMIKTVDLDDPVDCGKHFRSNINTGHIMSAGILADWGMRLAGFY
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MEAKGSRSADLLLDQKWDAAIDLTLRRVVYSSAGGAAAALTLFRSPTTRWSAIAFGAGIGLGSALRDCSYIFNGSDPIWPFSVGEGAERRASASE
The following text describes a protein:
Function:
Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA.
Subcellular Localization:
Nucleus. Note=Found in the nucleus of mitogen-activated peripheral blood mononuclear cells (PBMCs), tumor cells, or normal cell lines, but not in normal tissues except testis and fetal liver or in unstimulated PBMCs, suggesting preferential expression in proliferating cells.
Sequence:
MGSSKKHRGEKEAAGTTAAAGTGGTTEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGAERGSGRRGAEAEARSGAHGRERSQAEPSERRVKREKRDEGYEAAASSKASSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVAADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDSFREGETVVLTLKDKGVLQEGEDVLVNVNMVDKERADKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILAKYDEELEGERPHSFRLEQGGMADGLRERELEEIRTKLRLQAQSLNTVGPRLASEYLSPEEMVTFKKTKRRVKKIRKKEKEVIMRADDLLPLGEDQTQDGDFGSRLRGRGRRRVPEVEEEALEDEEKDPVAQPPPSDDTRVENMDISDEEDGGALPSGPPELEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVLEIVKKLESRQRGWEEEEDPERKGTIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQHQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK
The following text describes a protein:
Function:
Transcriptional coactivator necessary for expression of the clock genes PRR5 and TOC1. Antagonizes REV8 function in the regulation of anthocyanin accumulation. Involved in red light input to the clock. Activates clock-controlled genes with afternoon peak. Mediates light inhibition of hypocotyl elongation.
Miscellaneous:
MISCELLANEOUS: Unable to bind to DNA, but recruited to the evening element (EE)-containing region of the PRR5 and TOC1 promoters through its interaction with the DNA binding proteins REV8 and REV4; MISCELLANEOUS: The evening complex (EC) nighttime repressor is implicated in the temperature responsiveness by binding to the LNK1 promoter. Also responds to some extent to a dark/light transition in an EC-independent manner.
Subcellular Localization:
Nucleus.
Sequence:
MSDLYIHELGDYLSDEFHGNDDGIVPDSAYEDGGQFPILVSNRKKRRNDDMGSGTNHLKSNTFIKREANMLGKNPWPEKDSGGSSVSRDTGTGKDVQDMTLEDTNTSDHGFNGGHVDVVENFSTGDPMLCDTSAATNDGVYNYSLNSIPDAENDLSFFDNGDKEKNDLFYGWGDIGNFEDVDNMLRSCDSTFGLDSLNNEGDLGWFSSAQPNEETAGAMTDDLKPDKMLENQRTAMLQVEDFLNNSEPNHAVEDEYGYTIEDDSAQGKSSQNVFDTSLQKKDILMLDVEANLEKKQTDHLHHLDGKSDGFSENSFTLQHSGISREIMDTNQYYPPSAFQQRDVPYSHFNCEQPSVQVSACESKSGIKSENKPSPSSASNESYTSNHAQSIESLQGPTVDDRFRKVFETRANLLPGQDMPPSFAANTKKSSKTDSMVFPDAAPIQKIGLENDHRKAATELETSNMQGSSCVSSVVDDISLEATSFRQLQQVIEQLDVRTKLCIRDSLYRLAKSAEQRHHGGNRPEKGAGSHLVTGEADKYAGFMDIETDTNPIDRSIAHLLFHRPSDSSLSSDNNVLSYKSHPMIPQPNSSPSLRIEKQEETTELRPEAEVVTSDNN
The following text describes a protein:
Function:
Required for arbuscular mycorrhiza (AM) development during AM symbiosis with AM fungi (e.g. Glomeromycota intraradices).
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MSNERALIHNYKHGFSGFAALLSKHEANSIAQQPGVVSVFPNSILKLHTTRSWDFLKIQTQANTPSNSSSSSNIVIGVLDTGIWPKAQSFSDKGMDPIPPGWKGARYYLGGDESTPRDLYGGASYYGLAKGTSKGGSPQSRLAIYKVCSGGYCDDSTVLAAFDDAIADGVDVLSLSFGPDDPSSKPDLKTDSTAIGAFHAMERGIVVVCSARNSGRKPSTVSNDAPWILTVGATTIDRDLQSNVVLGNGKVIKGRSINFSPLSKSPDYPLVYCGSARDLDETRKGNPNSLDKKKVKGKIIVCVGSTEEEYGTDLKIATLQESGVIGFVYISDQEGADADNYGDFPKTIATTNMLPQSIIDAPFTPPLLMLPTG
The following text describes a protein:
Function:
Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKILKIPVFSLIEIPSIQAFQYVERRQPWLMRFSILVLSLQMAEKASRGTQDIPSSSPDENEFPFGYPTSICEDVPEQKYLCSNCNNVLKKALQTLCGHRYCSACLSWIVRNNKNPVCQKCKEEDPSTLSEGSLLAEERAFGDAAINKEISELRVHCVTLGCSWCGTMKNFEEHQILCEYALIPCHTGCGHVVMRKKLADHLENGCVNNVTVCHKCKQSLSSSEYQEHSCEDNLYREQKHVQAETPSDEKNHSGLSVSMDGCRFSEVGCSFGGSKEKIKEHEKAAVGTHMLLLLQYIKQLKANLCTVSKAANGFISQTELNVNGAEKSISELCIPGSLQVNGDLEVDCLTRTSVPRDESTVQQLVREKVISELENKLHVFENIVAVLNKEVETSNLEITAFRRQSELDQNVIRGLELKIAELHHCLTQKDAGLSRLHKSLVFSEQTSYDGVFLWKITDVNQKLQDSVTGRVVSLYSPAFYTAKYGYKVCLRIYLNGDGMGKGTHVSLFFVVMKGDYDALLPWPFRHKVTFMLLDQNNREHIIDAFRPDLASASFQRPVNDMNVASGCPTFLPLTKLQSPKHAYVKEDTLFLKCIIDAN
The following text describes a protein:
Function:
Binds to the upstream region of Rv1714 and probably modulates the expression of the downstream gene(s).
Sequence:
MSAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQAEIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRMATTVRLGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSAVGESFPLYCCANGKALLAALPPERQARALPSRLAPLTANTITDRAALRDELNRIRVDGVAYDREEQTEGICAVGAVLRGVSVELVAVSVPVPAQRFYGREAELAGALLAWVSKVDAWFNGTEDRK
The following text describes a protein:
Function:
Involved in pre-mRNA splicing as component of the activated spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MAAQGVSKAQYLQRYLSGPPAAQPRRRRKKKLPSGSGRAGMRIVDDDVGWSSIAAVPEKEEEEDEGDMPVVAEFIDERPDEVKLMEEFRTNSKWKLLGDRDEDSPSSDVSVPAKATTRQQRHDSPDNSPPRRVRHDSPDLSPPRQERNNSASLLPRKERQHGSPDLSPPRRKRHDSPDLSPPRRKRHDDSPDLSPPRRKRHDSPDLSPPRRKRHDSPDLSPPRRQRHDSPDPSPPRKKRHDSPDLSPQEQQTTPDLSLQRKKRYDSDPDSSPSLRKRARSPGHKKPSRTKDASPVKKLRRDSDSPPPRRGTQNASEADLSPQGKNHRALPSGKGQHGSKSPPDLSRHHYPDDKGSPKKGNMMSGVRAGLVSADVLRREQQELRKQERSSKHLEEESRHTETIFRDKSGRKRDLVQERLEQQQKDEAKSERDEQYARWGRGLAQGRQQQQNVEDAIKEMQKPLARYIDDEDLDRMLREQEREGDPMAEFIRKRKAKESKEKKEKPRYSGPAPPLNRFNIWPGHRWDGVDRSNGFEQQFFARMANKKAVQELAYKWSIEDM
The following text describes a protein:
Function:
Binds the phosphorylated C-terminal domain (CTD) of the largest subunit of RNA polymerase II and functions as a scaffold for RNA processing machineries. May be involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MLFSLGQRADSSTGWREFTRPEGRKYYYNKVTRTSKWRMPDEVKLAREKDITSHTSDFGSIPVVKTSSSGADSSLVSAHGAKSSPIAVSPTANLPTILASESSSLSGKVSSMMIETVEMKNSSEPSLPAVADSEKIGIAVTLGNSVAPPVFETTTAQDAVVYGDGFSSENRENVKKNAAITEIGGATPSDEKTVELGPLVYESKAAKSAFKTLLESVNIGSDCMWDQAMRAVINDRRYGALKSLGERKQAFNEVSLQKKLEAEERHVKQKKAREDFRIMLEDCKELSPSSRWEANSIFKHDERFKAAERAKDHEDLFEDYVEELEKKEHAKALEEQKHNKVEYLECLKSCDFIKVFVLWRKVQDRLETNERCSLLEKIDRLEIFQEYIRDLESKEEEQRKLWMEELRKAERKNRDEFRKLMEEQVAAGILNAKTNWRDYYIKIKDFAAYPAVSSNTSGSTAKNLFTDVMDELEKQYLDDKSQIKDAVRMAEIGLTLAWKLDDFKVAIAKYISSPPMSDTNLKFVFEELLERAREKEEKEAKKRKRLADEFYELLHASKILNDDDILDASVVSCVSTDILNADDILDASIVSSASTDTE
The following text describes a protein:
Function:
It is thought to provide protection for the cytoplasm during the desiccation stage of embryo development.
Miscellaneous:
MISCELLANEOUS: Wheat contains at least 10 different genes for Em protein.
Sequence:
MASGQQERSQLDRKAREGETVVPGGTGGKSLEAHENLAEGRSRGGQTRREQMGEEGYSEMGRKGGLSTNDESGGERAAREGIDIDESKFKTKS
The following text describes a protein:
Function:
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
Subcellular Localization:
Chromosome. Cytoplasm, cytoskeleton, spindle. Nucleus.
Sequence:
MCRVPAVMACKPLRSQGAVLRTYGRLRTVRRIQTQTWLSPADQKHLFSSSSSLLSSSQEPSSSCDPDFSPPKHHRARGKAPPSKKAAEPAYRKRKKKGRSNVGADVQEKENGPPSERKPASSLTISTPFRKFVTVRRKAPTRCNSVKRGRRTQAKNKAEHTIISSDSTCDFDLSRPFLRKKRKLCPDIGSILRSPTEISHSPLQKSPLLSSTPSVLLRAGVGRQKPLCETLEESVVRSCPAVKDQLETFNTRQEDFEPIRSSRRATHAQHLTRGQCAKDSGTDTRNVPDFISISSQSDQRGLPWNHTGARPSGNGSCLLLSSFAPVTISSSVSQSVICLDEDHHKGLPPGPRSSHVLCLSSELFSEDDFNSEAGGHGDCGASDHFLQEETVHEQPLVDPAPVLSFMGVPLGARSIKRMQPFVRLNSDLVTQYFQSRNGSSISALAGNRAEHHIVVPMCQVFNHSMVPPGEAGERSQGQSHNHAMVPPGEAGERSQGQTHNHAMAPPGEAEERSQGQTHNHAMAPPGEAGERSQGQSHNHAMVPPAEAGEKSHGQSHNHAMAPPAEAGERSQGQTHNRARSQEPSTCSWRDLSIREMQPVLRLDPNSMTKCFLQNGSETKENLPTDAELTWGGQCQQNRHPETSILLADDEADTCCPKGGAEISQHRANNHPARLQCHNSNHTTTKGWAHPPTGSSVGPLQPVVRLDPSSVPKYFLQRSTVALDPHSEGHLPTDPSGRKLHKRLCASPLLESITKTPNLADSHIEIKVQSCRTRAQETVGTGRKVCISGFSAKRWGNRLKKTRAQQQLSFRDSSDLSLRAFKELDPSLAAAQSPSSLLLSSSLWNSSFMNSSAVMNMSLSPGTSGPRDPQRERRHWLRLRAALSLHRKKKVQATEPLIHPPERSLHFALYSPQSLNASLTLQTSSLLLLSSRCASAGADDLSDAEKVYLECQQDGPIPFSSCLTQAQLACSQKIGEGAYGEVFRTFRGELQVALKVIPIEGTHRVNGEEQKCFSEILPEIIISKELSLLNEGKENRTNGFISLHSAHCVKGCYPPELLRAWDQFAEEKGTENERPDMFSHEQLFMILEFEFGGTDLENCQLPSVAVARSVLHQVTVALAVAEEELRFEHRDLHWGNLLIETCSSPTITASLHGDPITIPTSGVQVKIIDYTLSRLDKDGLTVFCDLSADEELFLGEGDLQFDIYRAMREENKNAWSAYGPHSNVLWLHYLADKLLSAVRYTRKPSSAPQRRELRKLQDLRREIRKFGSAGEVLGSKLFR
The following text describes a protein:
Function:
Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface. Essential for viability.
Miscellaneous:
MISCELLANEOUS: Present with 6840 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MFSFVQRFQNVSNQAFSMGIVMVVFIMASSYYQLINNNAFSVPSNIDNVKTLINVRTSRYFGSQRGKAKENMKIKFDLNTDLTPLFNWNTKQVFVYLTAEYNSTEKITSEVTFWDKIIKSKDDAVIDVNDLRSKYSIWDIEDGKFEGKDLVFKLHWNVQPWVGLLTYGETVGNYTLTVENKNKV
The following text describes a protein:
Function:
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MVQLSDVLGNVPLITRLYLILSFALMVLCSLDIISPLSLYLNWNLVLREHQYWRLITCFLYFGSFGIHFFWDVYVLIYYCSSLEEVTFRNNSADFLWMIILSCCMLLGVSYMFGGVYFYSSCIINVITYIWSKNNSTTRLTILFFTIRASYLPWALTLLSLIVDYNSNDNFFGILVGHIYFFFTSIFPHMPIAKNTNIFKTPRVLKWLLKEESS
The following text describes a protein:
Function:
May act as a GTPase-activating protein for Rab family protein(s).
Sequence:
MAAENSKQFWKRSAKLPGSIQPVYGAQHPPLDPRLTKNFIKERSKVNAVSLKNKKASSFHEFARNTSDAWDIGDDEEEDFSSPSFQTLNSKVALATAAQVLENHSKLRVKPERSQSTTSDVPASYKVTKSSSDAQLSRNSSDSCLRNPLHKQQSLPLRPIIPLVARISDQNASGAPPMTVREKTRLEKFRQLLSSHNTDLDELRKCSWPGVPREVRPVTWRLLSGYLPANTERRKLTLQRKREEYFGFIEQYYDSRNEEHHQDTYRQIHIDIPRTNPLIPLFQQPLVQEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFLSEYVEEDVENFDVTNLSQDMLRSIEADSFWCMSKLLDGIQDNYTFAQPGIQKKVKALEELVSRIDEQVHNHFRRYEVEYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLIKWRKEILDEEDFQRQVLVDRRISRGFSRLPEGELGAEGCVLLGRREARPFGTGDPGERGPFQGLLVPCSIVPG
The following text describes a protein:
Function:
Involved in cell density sensing and might synchronize the onset of development by triggering aggregation when a majority of the cells in a given area have starved.
Sequence:
MRLLLLLILIITINFSYGVLTPKNLAGEASEFGSFNIPNPMDVAQSSDSSLFGISMTQSQLKNSFEWSGVVPVDSEEEFTLTFFSSFPLSEFKVEASPKTSLSSSKSESEHKSKFYKVIKSIYQTPTVTNGSFGIDGATTPSFSLTWDKPVVGDWNVVITASSSLRKNEKFQKMVEDSTPQLLMLVQNPSDTHIYSYVSSYNNLFTGQKVSVLAMLHKKSEFIKKSSANRPLNWKPSPILLSDVSAEMILGLPDGSKETIPMFDDGLHDDEQANDGLFGGYINVSELGNYDLQVVYKGSQNGNGVIRSNQHLIPITSQYLELTGEVQSVQDGDANLNIYFIVNSPNQTTVDQTPVHVYSEVYGTDDDGKKVAIAWVAGVTSAQPIQGSTTTFALSAVLNERWIAKVGATAPFFVKNVQVSDLDTFIPLSNTTSTSNVKMVGEYKDVRTIVHSPPLHEITKEMRDGKMPKELADRIGKSTGNGKLILTHGYCSEGVWPIEDFENSVEFQDFNQNRGNDEFAQILANFGSQYTDGFSLVAHSQGGNAALHLVTFYFSGLDLSQKLEGRVIQSMGTPYQGTALAGTWASIGSAVGVGCSANDDLTVDGAALWLKSIPADKRALVYYTTTQYSTGSLINYCNLASNAVLEWPNDGVVDNEHTPLEGGVYLNNFKDWCHSDGMHSPQQTTNTEYNKEMSSNSVW