lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Cell projection, microvillus. Note=Co-localizes with RDX, EZR and MSN in microvilli.
Sequence:
MSSFACWSLSLLILFYSPGSGEKAFEVYIWSEKQIVEATESWKINCSTNCAAPDMGGLETPTNKIMLEEHPQGKWKQFLVSNVSKDTVFFCHFTCSGKQHSESLNIRVYQPPAQVTLKLQPPRVFVGEDFTIECTVSPVQPLERLTLSLLRGRETLKNQTFGGAETVPQEATATFNSTALKKDGLNFSCQAELDLRPHGGYIIRSISEYQILEVYEPMQDNQMVIIIVVVSILLFLFVTSVLLCFIFGQHWHRRRTGTYGVLAAWRRLPRAFRARPV
The following text describes a protein:
Function:
Binds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with oleoyl-CoA, barely with palmitoyl-CoA, but not with arachidonyl-CoA. May function as an intracellular carrier of acyl-CoA esters. Plays a role in the biosynthesis of membrane lipids including galactolipids and phospholipids.
Subcellular Localization:
Cytoplasm. Note=Also to the periphery of the nucleus.
Sequence:
MAMPRATSGPAYPERFYAAASYVGLDGSDSSAKNVISKFPDDTALLLYALYQQATVGPCNTPKPSAWRPVEQSKWKSWQGLGTMPSIEAMRLFVKILEEDDPGWYSRASNDIPDPVVDVQINRAKDEPVVENGSTFSETKTISTENGRLAETQDKDVVSEDSNTVSVYNQWTAPQTSGQRPKARYEHGAAVIQDKMYIYGGNHNGRYLGDLHVLDLKSWTWSRVETKVATESQETSTPTLLAPCAGHSLIAWDNKLLSIGGHTKDPSESMQVKVFDPHTITWSMLKTYGKPPVSRGGQSVTMVGKTLVIFGGQDAKRSLLNDLHILDLDTMTWDEIDAVGVSPSPRSDHAAAVHAERFLLIFGGGSHATCFDDLHVLDLQTMEWSRPAQQGDAPTPRAGHAGVTIGENWFIVGGGDNKSGASESVVLNMSTLAWSVVASVQGRVPLASEGLSLVVSSYNGEDVLVAFGGYNGRYNNEINLLKPSHKSTLQTKTLEAPLPGSLSAVNNATTRDIESEVEVSQEGRVREIVMDNVNPGSKVEGNSERIIATIKSEKEELEASLNKERMQTLQLRQELGEAELRNTDLYKELQSVRGQLAAEQSRCFKLEVDVAELRQKLQTLETLQKELELLQRQKAASEQAAMNAKRQGSGGVWGWLAGSPQEKDDDSP
The following text describes a protein:
Function:
This is a receptor for interleukin-21.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MPRGLAAPLLLLILHGGWSCLDLTCYTDYLWTITCVLETWSPNPSILSLTWQDEYEELQDKETSCSLHASGHNTTHMWYTCHMRLSQFMSDDVFTVNMMDQSSNSSQECGSFVLAESIKPAPPLNVTVTFSGRYDISWDSIYEEPSNYVLRGKLQYELQYRNLRDPYAVRPVTKLISVDSRNISLLPQEFQKDSSYQLQVRAAPQPGTSFRGTWSEWSDPIIFQTQAEEPEAGWDPHVLLLLAVLILVLVFMGLKNHLPWRLCKKIWAPVPTPESFFQPLYREHSGNFKKWVNTPFTASSVELGPQSPTTSVLHLSLYPAKGKKFLGPLGLEEQLECDGMSGPGHKCQGVSAYSEERDRPYGLVSIDTVTVGDAEGLGAWPFSCEDDGYPALNLDAVRESGPNGEDLLLVTDPAFLSCGCVSGSGLRLGGSPGSLLDRLRLSFAKEGDWTAGPPWRTGSLEGGSESEAGSPPGLDMDTFDSGFAGSDCGSPVETDEGPPRSYLRQWVVRTPPPVDSGAQNS
The following text describes a protein:
Function:
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKCPLELKEEILELNYQPPNHINLIGSYAYNTDFSKEQNDVDIIIEIPKECTHPKDYLNERILRRRALYLQHVAAIISKLSWVHKVTYLYRDGFDKLPILCLYSKPESVLASTRFLINTTIDSRAFKLHRYNIKKNNIRRRWYFKGTSKPIEEPLSMHYNTWVLNQLTCASNFEYLNKKLKDECSLQAGIKLLKMWMDRKALNKGYASGLFITAYVLFLLANEKLRANMSPYEIFRITLSNLGLFVIFSDILLTKFADDQFKPTMEDFHSCFDVVFVDVTGHVNLCADMNICMYDMLRYEASETSKFLSSNCVEKFELIFLDKTSYSSKFDHILSIETKESIKTLSVKSKKLQSHLIDYCGNYTLASFQLIIKVLKKALDNRIKFIACLPFDDVEVSSWSIFQQFVLYVLKSILLKLGLLLEPLNANIPEERGPPANSPQVHEFQKFWGEKAEQYRYAGGDIVEVVRWPKDNMSSARTIVPRIVKFILNRHFAFAKEAIQMTGSQLDHVLKPVEGKASSDSSIYGTGEEQHDDVIKSFDALSKALRSLEDLPLTFNTIQGLSPIFRYTEVFPPVQSTSQSDAVALQHRLIPGNNKNCPQFFPKFQVLCMMERSGKWSDDREVIRRLKGAFYIKLAELLKTKFNYSYLVYMDKLQLYKSPARYVFELKIGFSKELSLSRRVALPGGLVRMEDTPEYLETYRNLVITPTFTSYLHGIQQHFNSFSTTVRLCKRWVSCHLLGDHVNSDVIELCVAYLYTSLRGPYMPPGSPMVGFMQFLQLISTHDWKLQPLIVNFNEEFTAPDYTEIESFFHKNRSSLPSLFISTPIDRHFSYITSPSPLMLQRLIIVARASLKTLESLYLDLSVNKKEFKQVFRPPISDYNVLIHLDLLKCSRPQLGLDFKYTSEQPPPKPSSRSDECFPLVEFDPVLLYLRDLKESFNDFAYFFYDVYGGAFIAVAWRPSAYKGKPYDESSMKFNKLVEETLNSEQALMIADEEAIVDEFQSLGFGLVKNIEILKPIKFCN
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MGDKKDVGRTSSMENVSLRLERFPRDLLQRFTSSSRGAASSGAATQSQPSLEYKTPNQETEELELSLGLSLGGRFGVDKSSKRLTRSSSIAGSFPLFREDDSAATTTTPPAPSYTALVRSSSLPTETEEQWRKRKELQTLRRMEAKRRRSEKQRSVKDDRLEIETQVGVLAAKQGSSGYSDARSSLGSQTLQRRVSQDTVSSSGGVSVEQMTSTQRPDSSESRGKEISASTMEDMPCVFTKGEGPNGRRVDGILYKYGKGEEVRIMCVCHGNFHSPAEFVRHAGGGEVAHPLRQIVINPNPGPFPQ
The following text describes a protein:
Function:
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMVTVPPRHYCTVANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTALHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARKECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRGVSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKRVVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIRGPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPPGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVYDYREKRARVVFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRTAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPINLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR
The following text describes a protein:
Function:
One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MADTTGRIPLWLIGTVTGIPVIGSMGIFFYGSYSGLGSSL
The following text describes a protein:
Function:
Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity).
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MYVWVQQPTAFLLLGLSLGVTVKLNCVKDTYPSGHKCCRECQPGHGMVSRCDHTRDTVCHPCEPGFYNEAVNYDTCKQCTQCNHRSGSELKQNCTPTEDTVCQCRPGTQPRQDSSHKLGVDCVPCPPGHFSPGSNQACKPWTNCTLSGKQIRHPASNSLDTVCEDRSLLATLLWETQRTTFRPTTVPSTTVWPRTSQLPSTPTLVAPEGPAFAVILGLGLGLLAPLTVLLALYLLRKAWRSPNTPKPCWGNSFRTPIQEEQTDTHFTLAKI
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MTASALSKWPTCLACLRRLAQPFGTSAARHGEPRARAVPVIRPIVHTQTRAASHRMRLQDQGVVVRLLEDIPKFGRKHAIFRIERGRMRNEWFPKNKAEYMTPARFQELGLTRDAIGEVDRSFVIMSALEAATRPKPEEQKTEEPVPEVQISQVNVPDVTPETAHALLSELIPNTLTFHREPVPIPISQPKPALEPKISPLIARHVPASTPETPSTGEARRAIFGSVSSSDILNQIKALVSGHEEASRIVLGPSSVKIVGLAEDNDRIRHLGRWEIEIAVARAGGLDPVRKSVEILPSAQ
The following text describes a protein:
Function:
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation. During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work.
Sequence:
MRLRFPPYDVFKELFDPILEDLHGGYKPSDEHKPDLNPDNLQDGDDLAPNYVLSSQVRSGHSIRASASPHVPHCSRGEHGAREQLAVELRRAWTWPATWPVLALKSMTQAEQQQLIDDHFLFDEPLSPLLLASGMARDWPDAPDIWHSDSKIFLVWVNEEEHLRVISVQKGGNMKEVFPWFCNGLAQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGKHETFPKVLKRLRLQKRGTGGVDTAALGGVFEVSNADRLGFSEVELVQVVVDGVKLLIEMEQRLEQGWAIDDLVPAQK
The following text describes a protein:
Function:
Involved in cell differentiation. Required for the specification of stamen and carpel identities and for the proper termination of stem cells in the floral meristem.
Subcellular Localization:
Nucleus.
Sequence:
MGDGSSSRSNSSNSTSEKPEWLQQYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHSLNTYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLNQKSPAYDLLSKMLEYDPLKRITASQALEHEYFRMDPLPGRNAFVASQPMEKNVNYPTRPVDTNTDFEGTTSINPPQAVAAGNVAGNMAGAHGMGSRSMPRPMVAHNMQRMQQSQGMMAYNFPAQAGLNPSVPLQQQRGMAQPHQQQQLRRKDPGMGMSGYAPPNKSRRL
The following text describes a protein:
Function:
Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the first GlcNAc residue (with or without alpha 1,6-linked fucose), next to the peptide chains in N-glycans. Unlike in mammals, does not require the prior action of N-acetylglucosaminyltransferase I to generate complex N-glycans.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Domain:
The C-terminus (424-433) is important for catalytic activity or for enzyme stability. The N-terminus (1-78) appears to be dispensable for enzymatic activity.
Sequence:
MTARSIKLFFARWKYLMFACCITYLLVIYAPISKSEQKDWKEGEIELSNDHELDVPILQKEELKPQQRPSFEENVPKKKTFNFNPVGKEPFDVEEVLTSSDIKLEERMTATVIPGQKRLILSWNAGHSQDNLQGCPDWNCEFTQVRARAPDADAVLIAHMDNDFVPKPNQYVVYFSQESPANSGIQIPRPDYINMTLGFRHDTPAGSPYGYTVKLGAKSRKTGQVVDANLVNGKAKGAAWFVSHCQTNSKREDFVKKLQKHLQIDIYGGCGPMKCARGDSKCDTMLDTDYHFYVTFENSICEDYVTEKLWKSGYQNTIIPLVLKRKLVEPFVPPNSFIAIDDFKSVKEMGDYLNYLMNNKTAYMEYFEWRHDYKVVFLDGSHHDVLERPWGFCQVCRMAWTEPRQKVLIPNWDAYWRQTCEKDGTLVDSIPLD
The following text describes a protein:
Function:
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium. Required for the progression through mitosis through regulation of chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements including convergent extension during gastrulation. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Controls cell shape and not polarization of cells during convergent extension.
Subcellular Localization:
Cell projection, cilium membrane. Cleavage furrow. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton, spindle. Midbody.
Sequence:
MERSSSEETYSEAEDESQFGHFLRNDSEAELAGIIKGVGFDGSLHIQENNHSDQDQEKEDWLHNRQHQECGRIYNKQLEQERQSRRGQQQQEEESLWKEQQDEEILLRENQGEYLIKRQHEGDVRLHRKQLDEEERLRREHQEEKIRGQQYEEERLYREHQQDAWLRREQQEQKLRKQQLEQIETLQRDHLRLPKAQYEDKRVLKEKVSQLDYDILPNMIRHIKDDTEQEDGWEDEDSGLTMLPTKLCCPQALTPLSPSRPKSPWGRFDPYDSFEEDREYVGFATLPNQMHRKYVKKGFEFTLMVAGESGLGKSTLINSLFLTDLYRDRHILSPEERVTQTVEIVKQTVDIQEKGVRLRLTVVDTPGYGDAINNEICWKPVADYIDQQFEQYFRDESGLNRRNLQDTRVHCCLYFLSPLGHGMRPMDIEFLQALQDKVNIVPILGKADSLTPTELQQKKQRIRDEIDKYGIRIYQFPECDPDEDEDFKQQDIELKKSIPFAVIGSNTIIEVNGRRVRGRMYPWGVVEVENEEHCDFIKLRTMLIRTHMQDLKDVTRETHYENYRAQCIQNLTQRVVRERNRNKLTRESGTDFPIPSMPPSPDHETQRLIREKDEELRRMHEVLQKMQRQMKDSQ
The following text describes a protein:
Function:
Component of the DSC E3 ubiquitin ligase complexes that tags proteins present in Golgi, endosome and vacuole membranes and function in protein homeostasis under non-stress conditions and support a role in protein quality control.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSMEPPVGLTAMPVTKLAMITTLVVPLVASIASYKHIFLLQYDPFLQTYHQYYRLLIFQFCAINESDTVILALIWYLFRHLERLLGSHKYLTLIVLSWAYTTLGIWGLNLIWNAFIGQYKWLQWNNFSTGSLPIVLSLVHFYKEYTPQIYEWNIRLLGPRGGASSHNDNKREDKSAVEWKINDQFLLNGLILLLILNQGFAGILCGFISWMCGIFIDKGLLPGLDHWRIPFVSYFISQGPPTRANVAIAANAATNTAAARATVEAATAATGNGNTGNSGPTSLPLRGSSTTPTNTSSAGDDEPGADEPARPLGVQFLDTFRR
The following text describes a protein:
Function:
Forms the simplified baseplate, together with the p132 collar protein, the baseplate tube protein p140 and baseplate hub protein pb3.
Subcellular Localization:
Virion. Note=Component of the tail. Located between the baseplate tube protein p140, the collar protein p132 ring and the baseplate hub protein pb3 trimer.
Domain:
Possesses OB-fold domains probably serving host adhesion properties.
Sequence:
MRLPDPYTNPEYPGLGFESVNLVDNDPMIRDELPNGKVKEVKISAQYWGINISYPELFPDEYAFLDSRLLEYKRTGDYLDVLLPQYEAFRVRGDTKSVTIPAGQKGSQIILNTNGTLTGQPKAGDLFKLSTHPKVYKITNFSSSGNVWNISLYPDLFITTTGSEKPVFNGILFRTKLMNGDSFGSTLNNNGTYSGISLSLRESL
The following text describes a protein:
Function:
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Sequence:
MFTSTFNSFLLFLKIKGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSAQFVGNLRESPVGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGILIDLKTRYPLLENPEVLRKTADDFLSRVALTDAYLLFTPSQIALAAILSSASRAGINMESYLSECFMLKENRTFLAKLLEGMKSMKNLIKKYELPRPEEVASLKQKLEKCHSPELSLNTNVKKRKIGEDDEYSSKKPKMDENGLMKTLGTCEPIPVLTVLWHM
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MKALVFEVWDLMVCETRLSSKLPESSKIRLDTGKSKTPIKRPHLDAFLKRMAELFVLIPYTTRSRGVTDKVLDALEPDEHRFSHRFFLDSCGNGIHGKTKDLRILQWPMDQVIAVDDSCSKYDSHSDNVVIIPTFNRTDLRKDRVLLDLMPFLEGLAKREVEDVRPAIRARFFENFPVAKKGNRKRMFEMVLEKNVRPVETVLVDDPPIEDKNVVDLDPDEETNVVDPDEAMETKVSNLVEAMETKVSDQDEMEEMETKVSDQEMETKVNDQDEPVETKASDREEPVEERVKKVRWLIPEMEKNREEPVEEMEKVAKKETGRNEQPSERGRIKALARALLKVLRQPVLHPNLEMRPDGFCKLKELLELDFMTKSGVPLSSHTAAEAIKAVDKLTKKLAKMVDETGALYIGAPQEPVPPDGTGGDHEEWPHGSELEPDVSGDGSAGRGDRE
The following text describes a protein:
Function:
Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
Subcellular Localization:
Secreted.
Sequence:
MVSRKAVVVLLVVHAAAMLASHTEAFVPIFTYGELQRMQEKERNKGQKKSLSVQQASEELGPLDPSEPTKEEERVVIKLLAPVDIGIRMDSRQLEKYRATLERLLGQAPQSTQNQNAAK
The following text describes a protein:
Function:
Essential for sperm motility and is involved in the regulation of the beating frequency of motile cilia on the epithelial cells of the respiratory tract. Required for the establishment of radial spokes in sperm flagella.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme.
Sequence:
MLIPLTGQATCIYRLSLTPDEVARGLGTFDQYCPVCLARHCHLVDCSRTTSFALVAEYRKLYYKLCSEKHLEEFLSSPDQFVPPGCPHMLPQPHLLPKKLTEVEVKNRFPQHPELKGFCPVTYQEGKQRFEALVQGKAKYAVEYREQLYVFASQQKQEKFLRTPEAFWNQKLPKKVPALCEPVLLTSLPTLGYMEQGMANPLIKAMTAAGCLRPKYPFLSAQKSVLIYVGLYLKAFNPRSSEYSRQRCKKKLASFEEDCTLIPYLSAKMNCLPVEFSVDLQFKLNKFLALEGAASVLQF
The following text describes a protein:
Function:
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MGDSDDEYDRKRRDKFRGERSAGGGGDSYGRGADRPDRSRGRDDWPDRVRPRQDYRDYRPPPRDRGYSPAREGPTVKRMRGDTWGDEGRHRFGAHDGYGMYGYAHDHFGMHPTVGPYGHQHATHQREPVVSGDMQTQPCMMTLKQFLATQDDSISDSDAITKYNEYKLEFRRQQMNEFFVAHKDEEWFKIKYHPEESQKRKEEQLSFLKRRCEVFLELLKSKEIGKVSVDASNTDALLRLLDTVVIKLEGGTEEDLKVLDIKPSVVEAAARTPATLNEEKVKTESKVDATAKELAVKMEEDSSKQETETDVLSVPQSEEDARNGNSKIKEELSKSMDDGNENGDKSKSNDAQKSEKEIAEVEHEAHKHESEDRKKRSRSDSGSSSSSSSSSSSSESEEEKDERMNKEDNEDEENMRIPEEEKKSDSADTMDNINRDKEVDEGKPVCDAEDLNTADDRDDNADQNKEQNEFEETTKDKNSSDPVNDENKENSDKKSQQEGDSKAETIDLAKDPADGGSRALHRTSSIFLRNLAPSITKAEVEAMCRRYNGFLRVAIADPLLERRWFRRGWVTFKREVNIKEICWNLNNIRLRDCELGAIVNKDLSRRVRPVNGITCHKTVVRSDIKLGAKIAHNLDDKWGLWKETPTAASGTGEAGDKNGSEVQPEESFGLQSKNPVLQNITDYLIEEASAEEEELLGLSEDSKKVSEGELIERDPQLIEVLDRLILYLRIVHSVDFYNHCEYPYEDEMPNRCGIIHARGPPSQSKVMSNEIQEYIRTFEGKMASFLTRMVDIDETDMKKLGAKDAEAEVEKFITANTQELAKDKWLCPLSGKKFKGPDFVRKHIFNKHAEKVEEVRKEVEYFNNYLKDSKRPQLPEHPGNAKKPGSEGATSATANASVGAGGYRNQPFGMSHSYAPMYASYAAASMMAPNPRGRAGFGRGGRMGGPDYRPVIHYRDLDAPREPDEFL
The following text describes a protein:
Function:
Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis (By similarity). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids (By similarity). Required for plant vigor, fertility, chromatin condensation and sister chromatid cohesion both during mitosis and meiosis. Necessary to maintain normal structural integrity of the meiotic chromosomes during the two nuclear divisions of gametogenesis, especially to prevent interchromosome connections at metaphase I. Seems also involved in crossover formation during meiotic prophase I. Prevents centromeric and pericentromeric heterochromatin repeats association.
Subcellular Localization:
Nucleus. Chromosome. Note=Observed throughout euchromatic nucleoplasm. Associates with the chromosomes throughout meiosis.
Sequence:
MDEELLLTRILAGIEGGDDESDYHELVTDLKSLLDTDDDEILNRFYGSLSSMASSFLRCISAAMDSPVESGRLAILASDAYLSLLLSTNCPVFTFFSPIAFLSLLGSIRRYLKRRDDSAGQGSNSQREKGNKKKRGRGKRNLGYEDGEETEEGGFDAKLMFIVLEKLGSVLSFVHLDRFPDSLKSLVQTVSEIPLLALEHSGVLNYDRLMEMCGKILGGVLNSDHGDMALTAAEISKSLTPLLLMGKHQARSFALGFVSRKLMSLAKDNPELKKVVSNLPKFLVHKAPEKAEPRGFAVEAVLEIVKAMEVEGQSEFVDFVMKMCQGKSNFRVLAVDIIPLLISSLGNPLGDISSENGLKDSWGLGCIDALVQRCSDTSALIRARALSNLAQVVEFLSGDERSRSILKQALGFNGETSEGKGAVTDLLKKRCVDEKAAVRRAALLLVTKLTSLMGGCFDGSILKTMGTSCSDPLISIRKAAVSAISEAFRICTDEIVTTEWLHSVPRMIMDNETSIQEECENVFHELVLERILRAGNVLSPDSASLPNNRNTTSKDLDRDIEALFPEGVLVLLRELCNSEVSPWVTKICGSLGKKKRLKPRVALALQCIIKESESLWLSRSMPINRWTAPAGAWFLLSEVSVYLSKSVEWEFLHHHWQLLDKNDVQGLDEQGDEQGVECNSSTWAGDRVCLLQTISNVSLQLPAEPAADLADNLLKKIENFNLHSAEVDAHVKALKTLCKKKASTSEEADMLVKKWVEQVSLKASKVTEKYIEGVSSHNHSFVTPATLGSRRSKRLDTVSKKLSKAVTAVYTIGSCVIIYPSADTTKIVPFLHTVITSGNSDSKLKNKLPQANVCLKQKAPLLYSQSWLTMAKMCLADGKLAKRYLPLFAQELEKSDCAALRNNLVVAMTDFCVHYTAMIECYIPKITKRLRDPCEVVRRQTFILLSRLLQRDYVKWRGVLFLRFLLSLVDESEKIRRLADFLFGSILKVKAPLLAYNSFVEAIYVLNDCHAHTGHSNPDSKQSRTKDQVFSIRGNDERARSKRMQIYVTLLKQMAPEHLLATFAKLCAEILAAASDGMLNIEDVTGQSVLQDAFQILACKEIRLSVSRGASSETADIEEEGGDAATAKGRAITHAVRKGLIQNTIPIFIELKRLLESKNSPLTGSLMDCLRVLLKDYKNEIEEMLVADKQLQKELVYDMQKHEAAKARSMANQGVACGTSHRNGEPEASAASEENVRDSGLESRVVSAAADVVAAKAARSVLREVNGGAATPPLSAMSVPKLRSSRGVSQSGRPSADVLESLRRRPTFMSDDES
The following text describes a protein:
Function:
Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MKKILIIFSSVHGHTRKITNQLAQQLKELGNSVVIADIKAVPAMESFDKIIIGASIRHGKHNPALYEFIQKHQQILTQKVSGFFSVSLVARKPEKNTPETNPYMQAFLSKTTWRPKLLQVFGGNLNYQGYNAFDRNIIRFIMWLTKGPTDPVTNVEYTDWQKVQEFGLQIHQA
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
Sequence:
MFKTEFEFPEELKTKLQEHINYFPKKRQAILLCLHEIQNYYGYIPPESLKPLADMLELPLNHVEGVVAFYDMFDREDKAKYRIRVCVSIVCHLMGTNKLLKALENILGIKPGEVTPDGKFKIVPVQCLGACSEAPVFMVNDDEYKFESEVQLNEILSRYT
The following text describes a protein:
Function:
[Centrocin 1, heavy chain]: Has antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and against fungi with minimum inhibitory concentration (MIC) between 0.78 uM and 50 uM. Shows little hemolytic activity even at a concentration of 100 uM; [Centrocin 1, light chain]: Has no antimicrobial activity. Shows no hemolytic activity.
Sequence:
MMIKIAVVLCAVMATTMVRAKYVEEQELADLLDLLISEEVSSPDDAVALQGWWRRTVDKVRNAGRKVAGFASKACGALGHSPQEARAKVLEAFPEMKEADLDEEDIGKYCGYAHALNGR
The following text describes a protein:
Function:
Non-catalytic component of the proteasome.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDGKYGGYHTNTLNPTCTGTSVIAVVYDEGVAVMSDTVVSYGKSARYKNVTRQYKVNDRVIVAFSGDHADFHTLQNIIERQVSKWAVVGQKLNPSALYAFLTSLMYQSRCKMNPFWNTLIIAGWEDNEDGGKPFLGHITQKGVAFEAKHTATGIASHLLTQVIEDETRDKTALNRAKAESILRRAVELAIYHDCLADNEFEIGVVGKTEKASVHTQKPIIGDWSIAETNCQYE
The following text describes a protein:
Function:
Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (By similarity). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (By similarity). Associates with the NF-kappa-B complex and suppresses its transcriptional activity (By similarity).
Subcellular Localization:
Cytoplasmic vesicle.
Sequence:
MGRLHCTQDPVPEAVGGDMQQLNQLSAQQFSALTEVLFHFLTEPKEVERFLAQLSEFAATNQISLGPLRSIVKSLLLVPNGALKKGLTAEQVRADFMTLGLSEEKAIYFSEKWKQNAPTLARWAVGQTLMINQLVDMEWKFGVTSGSSELEKVGSIFLQLKLVVKKGNQTENVYIELTLPQFYSFLHEMERVRTSMECFS
The following text describes a protein:
Function:
Required for mitochondrial complex IV activity. May be involved in non-associative learning.
Subcellular Localization:
Cytoplasm, cytosol. Mitochondrion intermembrane space.
Sequence:
MSTRNVMITDLDQPDPNQQQHHQNPKKNRKVLQTLSGNFNRRSRSVEVEVKRQDNLGVVHKDRKKDRSFNSLLQAKDQQLEQLVQRLATLHRYNDQFAKENDQLRKDSGQLERRLTEAEQQVANCSRCQQLGQRLDTVLAQNRTLAGDVDMLKTLVFRLNVQIESYQDQRRLGEGAPTCGGSTKVSSSSAPYPPLPTHTLGPLLQAYDESLRDKDALLAQYNTEFEHFTGELKRALEENTKLLQSQEQLRRDLGGWREERVCLQAQLGVCRSKAEAQTRKTDLAKEKLVEVMHCYEQRMQTLILDMDHLQAAYARTKSELAALKSASSAAPAAVAPPVPAESEALHQCKALLEQLRQEHARERTCLQEQLQATTARAASLVRSTEKAKHSRDRLKARLRMALQWAQKLEAGQAEVRDTYEAVRRLEVLVQHKESQLRGLHARNAEEMDKLRHKLQQKEETICALLRGKMERRPAVD