lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a role in protein ubiquitination, sorting and degradation through its association with cdc-48.1 and/or cdc-48.2.
Subcellular Localization:
Cytoplasm.
Domain:
The PUL domain mediates the interaction with cdc-48.1 and/or cdc-48.2 C-terminus; The PFU domain mediates interaction with ubiquitin.
Sequence:
MADDGLGDVPMETESMPQYTISHVIEAHKSDTKALAVTQGGCLISGGRDETVKFWAKKGKQYTKTHAFEQPKGITVNSIAYAELADGWRLFVGRRDGTIAVFGPSQAEPYAIFNEHKQNVCCLHINEKATHMLSGSWDSNVIIWPITELNSSSFTFQTIVCPGHTLSVWALASFPDLPNTYLSASADKTIRMWFGDTTLSVFKGHTDVVRALVVLSSSHFLSAGNDGHIIHWDVASASILRKFATQAHEFIYSMTLSDSHILTTGEDGTLEFWAIDGGKDGNLAIVSEAVIQLPTTNTWDAKVLLNSDIAVAGSDGRIYIMTTDKNRKADDDILDAFDAEVVAKLTAKTERMKQEEHETVTIKVDIDDRPTQLNLKYKKGTDPGLCAQEFLSENNLPIHYLEEITRFIKDRIPEARAFDLKSGKKVIVDGKEYDYALGVNFGKGEPDKQMPFNVNESPQFAAQRFVERHQLPVSVIPSLAGMISQEMDKLSKGAASAQSGYEDPFTGPGRYVPQGSSNSGGHGADPFTGSGRYVPQASNSSGFDTGFSGDPLTGDGGYRASAPENTGSHAVPLSSLPQNKKKPRGPLVPVPDFYIIGLAGKGEKAIAKLKELNEKQDAFQLNPDQINGLEELFVLPTSSNYSSEVTQSAFEMSLQWPVEHLTPVLDFLRIALTHHSLNSYFCDRERGQELVGRLIAILVSDPADVALKVLVCRCIANAFSHPVGRNLFASTELSTLAPLVVRQVLNEKTVLQMSAATALANWSLALLQQSEQCEQLGPKEDLLRAILNGIESVDSFGYLGEDAIIRLLQALVTVMWGDASVIRLAKNRNIAQIAARLKDAVSNDSGKNIARDIVEMTYAV
The following text describes a protein:
Function:
Probably part of a binding-protein-dependent transport system YnjCD. Probably responsible for energy coupling to the transport system.
Sequence:
MLCVKNVSLRLPESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLFSWMIGALAEQFSCTGELWLNEQRIDILPTAQRQIGILFQDALLFDQFSVGQNLLLALPATLKGNARRNAVNDALERSGLEGAFHQDPATLSGGQRARVALLRALLAQPKALLLDEPFSRLDVALRDNFRQWVFSEVRALAIPVVQVTHDLQDVPADSSVLDMAQWSENYNKLR
The following text describes a protein:
Function:
Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Cell surface. Endomembrane system; Single-pass type II membrane protein. Secreted.
Sequence:
MINMYQTNLPPPPIPPRLGSVKSAPGPGHNKPLLGFLIGMIVLQMLLLLGGFAYLYHKENKYDKDFEHKYLDDMIVLRRLGECEKDSQSVLDCEKLVEKYKNIMEKVSQVEGKAVKLTGGVPTYGAMARMIVKQPVVGALPSSNYLEWNIGHSVLRNVQYFKSSWLKVLQPGDYDIYSQVAFSKWHPKAPLASRVKLRKGETGEEKNLMTAYCSLGDQNRTDVCTAFQGGVFSLEPKDQISVWVTDPSLVNYEEGTTTFGLYKL
The following text describes a protein:
Function:
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
Subcellular Localization:
Nucleus.
Sequence:
MREFFGCYLLASQSPKHKGRTYIGFTVNPRRRIRQHNGLIKNGAWKTHKGRPWEMTLVLYGFPTKIQALQFEWAWQHPERSLIVRPIAQALGRQRMQGVRGKILLMLSMLHESPWRHFPLTLQYLAPQYAALIKESVASAPTHVRVFTAPMEELPKALDDMDDDEEGEQPEGEAGEEQGSAERGAEGEGGAEDDTASEGGLGGGSDAEADADARGLGYGSGGAAGGGGGSESDGDVELLEDEPFAAGAADAGPCHVSGKTATGAAAGGAAAAAVEAATAAAAAVAACGKAPCALCSAVISRHMLYCATCASPFHLDCMAARWAATAVPAAADAAVAWSAGGGGGGSRFGGVPEQGSCPACGAAHTWMELLRGMQTVGWGNKSGRRQRRGAGTKAAAKCAAGGTKDISTGAGAGGAAPGGSKRAATGKAGGSKARGKGAIAAAATAVPGDPDAAHGLEGGPLPAGTLAAAAKPRKRTAKPKAATAAAAAAAEARATAAGGGLCDWAEAGRHRGYMAAAEREGEQLSNAAATVEPGAAAAAGPKGRGAGATTKPRKPRTKAVVGAAAPAAGGEAPEGAAALAKPRGRRKAAATAAAASAELEPTAAAGYTVAEGDPVAWAATEFSGPVAVASRGGGAAGSPAKRQRKGAKGAAAVATAEAAAAAAAHATAPGRQRAAGPRVESGGGEEAVAGDHDASPVPLWRRLQARGGAGGSGSSKAAATAAPAAPPAAGMYDDEDDEGGDEIEVVEAGGQAAAAGGGRGRHATRSIALSSSASPSPSTSPAASRSPSPAPLLARGRGGSSTGPAAGAAARARRVGGGGGGNGAAAAAAEGTGWGHMQVRGRSHGWDAPARDEAAEGGLYARRMVTDTRRAGMEAQEAAAEEETEEEEEMLHGWQAAGHQHSHQDSQQVELVILGTSSEEEDQDEEEGMEQEGEERDNPDQEGDQEESGRMQDLQEELAEELGEQAAGAAAPGTGTGTKAAADCMDVDADVGVGADADGFGSPVIAATADPGPSSHGTAVPRPDQHRGQTQQGGQQLWRLQRAGEAGDEVAVQERKAHTPPQPRPQRVGGLPGDSTRAGGGGSGGASGGSGNGGCGEAVLSAGGGVTAMLAQLQCAGSTASPPPPPAAAIAAAADCVAAGAATAAATVQHGQLRHQPFPEQQSQQQQWQGQQGHEPREVVDLCTPLPPSKRLAGRTVPSEAGAGRRGSQAAGAVGTAGEAAATDRGTAVQACGVSKRLRSPKPPAGGEQHKEWGAAAAPVAEATAAGQAAAGRGGPSRQPAGPPRAAPARGAATAATGAAAGAAAAGAPGEIASASPGGWAVSPWPVRQRLLAESDRDEEEAGAAGDFGGGGASGGPAAPDDDDEMSDDVIIID
The following text describes a protein:
Function:
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MEMAIGIGMFTLVVCLLVIVILIAKKKLVTTGEITIGINDDAEKSIKVAAGDKLLGALASKNIFIPSACGGGGTCGQCRVKVKSGGGDILPTELGHITKKEAKEGCRLACQVAVKTDMELELEEEIFGVKKWQCEVISNDNKATFIKELLLKLPEGEDVHFKAGGYIQIEAPAHVVKYADFDIPAKYRDDWEKYGLFDLVSTVNEDVLRAYSMANYPDEKGRIMLNVRIATPPSANVPPGKMSSYIFNLKAGDKVTISGPFGEFFVKDTDAEMVFIGGGAGMAPMRSHIFDQLKSKKTKRKMSFWYGARSTREVFYQQDFDTLAAENDNFVWHVALSEPLPEDNWTGYTGFIHNVLYENYLKNHKAPEDCEFYMCGPPIMNSSVIKMLESLGVEPENILLDDFGD
The following text describes a protein:
Function:
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Sequence:
MFDGLKDKLSNFREDAEEVAEENAEELADQPDDEAADTEAAAADSAPEDAPATADAAAPATEPAGEQPDADDEESSAGFVSRAASMARGRVVIDEADLEAPLRELEFALLESDVEMSVVEEILDQIRGDLVGEERKFTESTDTLIEDALREALLSVIDVGQFDLVDEIESTSKPVTIVFTGVNGVGKTTTIAKLARYLESEGFSSVLANGDTYRAGANQQIEEHAEALGVKCITHEQGGDPTAVVYDAVEYADANDVDVVLGDTAGRLHTSDDLMSQLEKLDRVVDPDVTVFVDEAVAGQDAVNRAREFDEASAVDGTILTMADADSQGGAAISVSHVTGKPILFLGTGQAYEDLEPFDPDALVDDLLAASDD
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLLRVQVKNEFGLGKSDLYVDSNNEDPKAVLDAVAVAGLVGILRQLGDLAEFAGEVFHGLQEEVMTTASRSHKVMLRVKQIEAALPSLEKAILAQTSHIHFAYTAGSEWHPRIRTEQNHFIYHDLPRFIMDAYEECRDPPQLHLLDKFDTGGPGSCLKRYSDPTFFKRMSTSGKISLEKVRSDKKAHKIKRKRSSVRNGKTVHGASGSNANSSLQFTSFSNEGASRSQTATADRRIKSDAGDSSNSFDSGRGSGYAGSVLKLDSSLQTKEQEFRESSSSSLMQFSDAVDSVLADEQSRIIDDKYQCALEDQIDSSFSSHVTWDEKEEIFKPKQEVREKIAVVESRGQEDAREMAETLQLRTHLYVSEMAEFVHLRSQKDVREMEEIVQPRTKQNVREMAEMVKPRTQQDVRGMAEIVQSRSQKDAREMEEIVQSRPEQNVGEMAEFVHLRSQQGVREMEEIVQPRTKQSVREMAEIVKPRTRQDVRGMAEIVQSRSLKDVREMEEIVQSRTEQNVGEMPEIVQPRTQQDVREMAEAVPLREVEEIGQPRPEQYVRKITEIVQPRTQKDVGEMAEIMQPRAEQVFREMAEILPSRTQQDVRNMAEIVQPRTQQGGLEKPKMVEHGSQQGGRDQVEMVESRSQQHDKVKDQEYKVPLPESTQEPHETEGFYLINDEPMNMLANNGHPLESIYDGNMFDEIESETDNYMDALNTIESESETDLDCQTKREVEPCSSNIKCEVVDPTHDLLESSLGPDILILNPSNEPQESFDKGIVSSLPNLVSSDSFFHDQRLESTMKISSPDCPLVTDLHGKESSTMESDVSDSFPPDSNSSLEDQPGIKLLNRVHESETASFSSNLSDKFWTNGGLLGLQPSKPPSWAVPNAACEDSSKVEKRGPSDLAYVVSSNPQEIKLNNLPKDVINSEKDSTSNKSSLHHDDQKYDTSGRVSTSTPSQELSRGNSNAKNGSFSVDRSSDGSTYAYMNDVVKRNVIAAGIASPAVPNVNGMHTQTILEKDENSNQNSGLSHQLLVNGFHRKLTLIHDERFETTSMTTDGPGKRNANQDTVLQTMYERTSKEHLGCDSSMDSCPPSPPLDHMKISFHPVSGFEISKMKLRFPDGSEGRGSTKDIFPSFQLAPEESISVHEIGSESDDDTFCRSSPCMSDDCLSDHSKSNSDLWESDDTPETTGNNLYDLRHMSHVESLSTSFELEGITKNGIMMDDESGNLNGKVMDESLSGSLLDLPCFDIVNPVTSGRIDSFALEGDSSYCAFQTGHNDVDATNLLRPQCLDSPTPAPPPLPPAQWCVSKTSLDVSDDLKDLSAHPKQVEPIAFVQQITHASDATKPNGKKPEQVVVDSQKELNHRRNDQVMDSREDFLQQIREKSFNLRRTVTEKPSTPAGPAAHVKVTAILEKANAIRQAVGSDNGEDDDSWSDA
The following text describes a protein:
Function:
May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover.
Subcellular Localization:
Cytoplasm. Nucleus. Note=ESXR1-N localizes specifically to the nucleus while ESXR1-C localizes specifically to the cytoplasm.
Sequence:
MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF
The following text describes a protein:
Function:
Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.
Sequence:
MLSALMLALALPAYAAQQTLALNWKAETQFGGFYAAQYSKAFERRHLDVNITEGGSGTPTVQILAAGRVNYAIVSGDEIAIAHDRGADDVVALFAVYQTNPQCIMTHAERGFAKIDDVLQNDGTLLWQAGLPYAQYFRKKYAPIKVRSAPYLGGIGQFQHDPQTSQQCFITSEPLTAEKAGIKVKAFLVADSGYNPYTTVLATTRNYLQQHPDEVRAMVAAVREGWSNYLKDPAATNVQMATLNKAVSLDNLNAGAKAQQSLIQATPNGKLGAMTTARWQQLVEQLQQLGVIHKPVAADKLFVDL
The following text describes a protein:
Function:
Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MHEMQGILLCSGGGTRMPVLTRHVQKCLLPVVGVPMFLYPLSSLLRTGITDIKIFVREVLQLTLEKEVKKSKLLEKYPAHIEYICVNQEDFGTADLLKNHHSKITKDALIVSCDFISDASLIPLVDFFRATNSTLVALIADTCVNAPAPGSKSKKPKATDVMAIVESTGQLAFLCGDDDFDAPLVMEKSLKIFPSIKLTSKYNDCHVYAIRHKVLLNLSKSKHISSFKADFVPLLIDKQFEPDSDIKCFAYRLPHENGFVTAHANTLGSYFEVNKAIQKSFTRLMEYRGNGKNFNYKTDKIAAHESRIEESAEIDKDSVIKRSFISDNCRIGEKTKLKESIIAKGVVIGNGASISNSIICDGVEIGENADVTNCIVAKDQKVPAKGKVQNEVVEDGEDEEWTDD
The following text describes a protein:
Function:
Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
Subcellular Localization:
Cytoplasm.
Sequence:
MIIVTNTIKVEKGAAEHVIRQFTGANGDGHPTKDIAEVEGFLGFELWHSKPEDKDYEEVVVTSKWESEEAQRNWVKSDSFKKAHGRTKDTREQREDRKGIVGNAIARFEVVHVQNPVIVEK
The following text describes a protein:
Function:
Sesquiterpene synthase involved in the biosynthesis of volatile compounds. Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (1E,4E,8E)-alpha-humulene and (-)-(E)-beta-caryophyllene, and of (2Z,6Z)-farnesyl diphosphate ((ZZ)-FPP) into beta-bisabolene, gamma-curcumene and (Z)-gamma-bisabolene. Can act with a low efficiency as a monoterpene synthase with geranyl diphosphate (GPP) as substrate, thus producing beta-myrcene, (E)-beta-ocimene, limonene and terpinolene.
Domain:
The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
Sequence:
MASSSANKCRPLANFHPTVWGYHFLSYTHEITNQEKVEVDEYKETIRKMLVEAPEGSEQKLVLIDAMQRLGVAYHFDNEIETSIQNIFDASSKQNDNDNNLYVVSLRFRLVRQQGHYMSSDVFKQFINQDGKFKETLTNDVQGLLSLYEASHLRVRDEEILEEALTFTTTHLESTVSNLSNNNSLKAEVTEAFSQPIRMTLPRVGARKYISIYENNDAHNHLLLKFAKLDFNMLQKLHQRELSDLTRWWKDLDFANKYPYARDRLVECYFWILGVYFEPKYSRARKMMTKVIQMASFFDDTFDAYATFDELEPFNNAIQRWDINAIDSVPPYLRHAYQALLDIYSEMEQALAKEFKSDRVYYAKYEMKKLVRAYFKEAQWLNNDNHIPKYEEHMENAMVSAGYMMGATTCLVGVEEFISKETFEWMINEPLIVRASSLIARAMDDIVGHEVEQQREHGASLIECYMKDYGVSKQEAYVKFQKEVTNGWMDINREFFCPDVEVPKFVLERVLNFTRVINTLYKEKDEYTNSKGKFKNMIISLLVESVEI
The following text describes a protein:
Function:
Sesquiterpene synthase involved in the biosynthesis of volatile compounds (Ref.1). Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into beta-cadinene (Ref.1). Not active with geranyl diphosphate (GPP) and geranylgeranyl diphosphate (GGPP) as substrates (Ref.1).
Domain:
The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
Sequence:
MAEVGLSQNSYASANHDKKSEQQIRRRVAEFHPNVWEYEFLQSLSSPYGAPSYCERINILIEEIKMDIFDGLVGDGEKNMNPSAYDLLERFFVVDILQSLGIERHFKKEIKAVLDYTYKYWNDEKGISLASGNLIVDLNTNALGFKVLRLNEYYVSPDVFQNFQDEMGQFIDLENFKEDESKLRSLLSLYRASEICFPEENILKQAKMFASTCLRQAIEENRELVNKSQLIIEVEYIMKYPWTCRVPRWEVWNYIKIFRGDTDASMCMKGVYEMPSDKRTKILELAILDFNILQDQHHNELKILSKWWNETKVKELNFFRQRHVEFYFLYACGLYEKELSATRLCFAKVGALITLLDDIFDTYGTIDELVPFATALIKWDMSIMNHLPEYMKTCFQFAYKTYMEIATEAEKIHGPCVQKWMHDTWKTIILAQLQDAEWIANNYLPSLTEYLESSVPSTTVPVLSLFSMLLIDTIFPDDIIEKITKFQSCVAWGCRLVDDSKDFQDEKEHGESASWIECYMKENPGTTRKQALDHANMLIESNFEELIKHRIFYEYCIPSTCKRLYFDMYRSVAFIFKDIDGFSKSSKAIRDDIKKILVEPIYF
The following text describes a protein:
Function:
Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MVSWMICRLVVLVFGMLYPAYASYKAVKTKNIREYVRWMMYWIVFALFMAVETFTDIFISWFPFYYEIKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDTCIVQAKERSYETMLSFGKRGLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDAPAPAYQDPLYLEDQVPLRRRPIGYRAGGLQDSDTEDECWSDTEAVPQPPARPREKPLNRSQSLRVVKRKPPVREVSGQEGVREAGCPGTLAYTSSRCICSLPSGYLALPEGSDKEKDHFFRHEWLGSAEPGRVLRLALWGTRDCLEGATGCTSDLPTPAAQAVSSWLLLSVRGWGGAQGYTCDVPKQAGPMILFIAFLILIPSWVCGTRALPRPLQVKPKVHPAVFIPSCPSKYLTASSKAPCVYMCVCVCAHVHVFPGCVLCW
The following text describes a protein:
Function:
Negatively regulates the expression of the glaH-lhgD-gabDTP operon in a temporal manner during entry into stationary phase or during the first few hours of carbon starvation. Thereby is involved in the regulation of a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Binds to two primary and two secondary sites in the promoter region of the glaH operon with the consensus sequences TTGTN5TTTT and ATGTN5TTTT of the primary sites, each separated by six nucleotides.
Subcellular Localization:
Cytoplasm.
Sequence:
MTITSLDGYRWLKNDIIRGNFQPDEKLRMSLLTSRYALGVGPLREALSQLVAERLVTVVNQKGYRVASMSEQELLDIFDARANMEAMLVSLAIARGGDEWEADVLAKAHLLSKLEACDASEKMLDEWDLRHQAFHTAIVAGCGSHYLLQMRERLFDLAARYRFIWLRRTVLSVEMLEDKHDQHQTLTAAVLARDTARASELMRQHLLTPIPIIQQAMAGN
The following text describes a protein:
Function:
Binds to chondroitin sulfate on the cell surface to provide virion attachment to target cell.
Subcellular Localization:
Virion membrane. Note=Component of the mature virion (MV) membrane.
Sequence:
MPQQLSPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGGYISGGFLPNEYVLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFLQVSDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSTLDYFTYLGTTIKHSADAVWIIFPTPINIHSDQLSKFRTLLSSSNHDGKPYYITENYRNPYKLNDDTQVYYSGEIIRAATTSPARENYFMRWLSDLRETCFSYYQKYIEGNKTFAIIAIVFVFILTAILFLMSRRYSREKQN
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSAKPAMESVSFEDIAVYFTWEEWQVLDVAQKLLYRDVMLENYSSLVSLGCCVIKPELILMLEREFGPWRVADTSIWNLPGYCITRPELNIKLQHGFEPWSGSEASLWNLPDVHNVSALGNQETHLWQAEVTGGITSYEQMVEAELQIQEKIHRGAKTCEYKECVETFYPNAQHTRNQTSQSYENAYGWEECKKTFYYQSTLTQHQRFHIGEKLYDSPQCWEIFPWKSQLSVHETFHAGERRYECEECRKSFHRKANLIRHQRRTHSREKPYECIECGKTFYCKSDVTRHQRRTHSREKPYECVECSKTFYCKSYLIRHQSRTHSREKPYECTECTKTFYCKSDLTRHQTTHSGEKPFECNECSKTFYYKSDLANHQKTHTDDNPYECKECRKTFCSKSSLNQHHRIHTGEKPYECNECKKSFNSKSNLTEHQRRTHTREKPYECSECWKSFYCRSELTNHQRTHTVERFYECKECRKNFYCKSNLNQHQRTHTGEKPYECKDCNKAFYCKSNLNQHQRTHTGEKPFACKDCSKAFYCKSSLVKHQKIHSGEKPYECEECRKTFFQKSDLTRHQRTHTGEKPYECTDCSKTFYCKSNLNQHRRTHTHEKPYECEECREAFYSKSELTEHQRTHTDEKPYVMFNIDCQLDKIWNHLGDRPIGMPVKDYLD
The following text describes a protein:
Function:
Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.
Subcellular Localization:
Lysosome membrane; Single-pass type I membrane protein; Lumenal side.
Sequence:
MGCTRGWRLLLLLGLVCVGALQGRGQEESREVSLQYNPGSSDTSVNVVHVRAVGNGSTIHYVWSTIGTPTVLLIFTHSETSQLQVNWTKLLSPAPQGALRIEPAESVSYATALLFTRIFEYQDVNNTANFSGTDEKYFYPAYNLSDFLWDSANATINATSLSANLTGYNASDPTDSFHNGSVSFRISAYSSSGRDSSSPRLRHTANCTKLEFLVAGVRPRGNNSRFALEMVTIEKEGRKKMESVHSIDDEYTPTIFEMMQLVPDAPNSSHARGFLQWKSVAYGSPSGTRADILPCQLHPLRPFNTTFPAGSIAHAYFGDDLADAYKLEAFNISFGIADGDFYDKNRFLSWSALIGYGEPPRDSFSILVICIMAVALGTPLLLLIVGTLVVTALRHKVYSNYEPIN
The following text describes a protein:
Function:
Electron transfer pathways that operates during photosynthesis.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MLVKTHITKIGVTLFAVALFYGFIYMLSNSLFATRPATAVAVGADGKALLPSVDEAAMPAKAPAAAAPAAETAEAAAPAEPAAPPPPAYVEVDPATITGDAKAGEEKFNKTCKACHKIDGKNAVGPHLNGVIGRATATVEGFKYSTAMKNHVGNWTPERLDIYLVSPKAEVPGTKMSFVGLPEAADRANVIAYLNTLPR
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MEMSLATIIFTFTFTFCTIFIIPCSEAAEKGQGNGLHVGFYGIRCPNAEQIVADVVSKAVEADQKLPAAFIRLFSHDCFVKGCDASILLDSTPSHEPVEIQSPANVGIKGLEVIDEIKARLEAECPETVSCADILAFAAREAVALAGLPRHKVPAGRRDSRTSRATDVTLPAPATPLNEIIEYFSRRGMTSDEIVVLSGAHSIGAVHCSFFDYRLYNYDQTQAQDPALDRFYAANLSQQCPAPNTLPEAEAKNRVVDFDPITPLVLDNQYYANLMQGKALLQSDQALVTDPRTKAMVISMAASADSWTQRFVRAMIKMGRINVLTGENGEIRKNCRAFNPL
The following text describes a protein:
Function:
Involved in pre-mRNA splicing as a component of the spliceosome (By similarity). Required for normal accumulation of ik (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Nucleus speckle. Note=Colocalizes with srsf1 in nuclear speckles.
Domain:
The WD repeats assemble into a seven-bladed WD propeller.
Sequence:
MSIEIESADVIRLIMQYLKENSLHRTLAMLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQSLKWQQHQGLLPPGMTIDLFRGKAAVKDVEEERFPTQLARHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMSFSRDTEMLATGAQDGKIKVWKIQSGQCLRRYERAHSKGVTCLSFSKDSTQILSASFDQTIRIHGLKSGKCLKEFRGHSSFVNEATLTPDGHHAISASSDGTVKVWNMKTTECTSTFKSLGTSAGTDITVNNVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDYVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP
The following text describes a protein:
Function:
Inhibits DNA replication early in developments. May bind and block the action of a replication or initiation factor.
Sequence:
MGEINALSCVGQDDVVSLRIVCTMARDGKQHNLEDVDMYGNTALLKACYLGRFECARTLLEFGANIFAMNYFGQNALTLATYAGHLTLVKELLRRRSYKDFNLSSMIPALCVATLQKHSALVAYFTQLDSRGVQETQTVHGLGVAELRGMIKAAGRLDKRNVRSPPTFISNRLR
The following text describes a protein:
Function:
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Confers sensitivity to ABA during seed germination and early seedling development.
Sequence:
MTFRSLLQEMRSRPHRVVHAAASTANSSDPFSWSELPEELLREILIRVETVDGGDWPSRRNVVACAGVCRSWRILTKEIVAVPEFSSKLTFPISLKQSGPRDSLVQCFIKRNRNTQSYHLYLGLTTSLTDNGKFLLAASKLKRATCTDYIISLRSDDISKRSNAYLGRMRSNFLGTKFTVFDGSQTGAAKMQKSRSSNFIKVSPRVPQGSYPIAHISYELNVLGSRGPRRMRCIMDTIPMSIVESRGVVASTSISSFSSRSSPVFRSHSKPLRSNSASCSDSGNNLGDPPLVLSNKAPRWHEQLRCWCLNFHGRVTVASVKNFQLVAVSDCEAGQTSERIILQFGKVGKDMFTMDYGYPISAFQAFAICLSSFETRIACE
The following text describes a protein:
Function:
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
Subcellular Localization:
Secreted.
Domain:
Calcium binds to the gamma-carboxyglutamic acid (Gla) residues in the Gla domain. Calcium can also bind, with stronger affinity, to another site beyond the Gla domain. Under physiological ion concentrations, Ca(2+) is displaced by Mg(2+) from some of the gammaglutamate residues in the N-terminal Gla domain. This leads to a subtle conformation change that may affect the interaction with its binding protein.
Sequence:
MADAPGLIPIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVQGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQAGFEGRNCELDATCSIKNGRCKQFCKNSPDNKIICSCTEGYQLAEDQKSCEPAVPFPCGRVSVAYNSKKITRAETVFSNTDYGNSTELILDDITNSTILDNLTENSEPINDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEHNIDEKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTKFSIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
The following text describes a protein:
Function:
Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis.
Subcellular Localization:
Cell membrane.
Sequence:
MHTDFDTDMDTDTETTALCPSSSHQASPPETPTPEADATLLKKPEKLLAGLDRGRPPPALGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPTQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHELENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEGPASPPSRAQRSPVGGRAPEEVPSCRGPPSGRDTELQAHRDVGRAAPQHEGALRRSGAPDPAAAGPEWRRGPAARVGQPRGPRSACASREPHQEGQALPCQPGAAQRQVL
The following text describes a protein:
Function:
Baseplate protein that is part of the outer wedges of the baseplate. Probably plays a role as a connector between the central and peripheral parts of the baseplate. Plays a role in tail assembly.
Subcellular Localization:
Virion.
Sequence:
MTARYLGMNRSDGLTVTDLEHISQSIGDILRTPVGSRVMRRDYGSLLASMIDQPQTPALELQIKVACYMAVLKWEPRVTLSSVTTARSFDGRMTVTLTGQHNDTGQPLSLTIPVS
The following text describes a protein:
Function:
May play a role in mRNA degradation. Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits.
Subcellular Localization:
Nucleus.
Sequence:
MAKSKVEHVVVDAVAFFRQVHLQDVAENVHTLRAVVNEIRDKATRQLLAVLPYEIKFREPSTECIQIVSDFARKTGDYQSLSAVDIRVIALAYQLTKEYVGVDGLKKQPETKITYSASSKPLQKAKDIAGFYYPASKDASKDSNAEHDKPSPGTTEDNMRTGDIQLELNDQVCKDEEEDKEKMETTVEGGCGMEDERTCDEVMKEEEGEASVDAGKDSEEDERRIEEENKMEERTDQCDEAESKPEQSQSEDAGIDDTSCDMNDGDEGIVEGEEEEEDDDEEDNIGWITPQNISQVREQMAGSGETNLEGIKVGCMTTDFAMQNVLIQLGIPVISVNGMLIKHAKSFVLRCHDCFKVTHDMGKVFCPKCGNKSLDKVTMTIDEDGSRRYHMSRRRPVNTRGLRYNLPKPQGGKHTSNPILYADQRIPQNREARKGNKKTNVFDPDFDAMGSPFATHDVTSRSALLGVRQLGGQGSGSRRNPNENRRQSKKGKRR
The following text describes a protein:
Function:
This protein is involved in nucleosome assembly. It is bound to H3 and H4 in the absence of DNA, but released from H3 and H4 in the presence of DNA.
Subcellular Localization:
Nucleus.
Sequence:
MAEETAALSTEKTEDTSTAPSTSAEKADGIDIDTEAKRLMGAGQKHLVMKDVRSAVNLFQEASSLLAKQYGETADECAEAFYSYGMSLLELARLENGVLGNALEGMPEDDEEEAEKEEDPNIPSADNLDEKEREQLREQVYDAMAEDQRAPDDTSESEAKGKPEGDSKDKEADEKMKNGQKETEKVTDDLKIDSASRDVPMDKSGKGEPPESKDAETLVEQKESKPETLKEKSIETKEKDLSKEKTDAKETANQSPDSTEVAEEKMDSEASESKESTSIPPTENEANKPDDPEKMEEEEEGEDSEENEDGTEENEGTEEKETEEEDVGNLQLAWEMLDLCKTIFKRQQSKEAQLKAAQAHQKLGEVCIESENYSQAVEDFLACLNIQKEHLEEHDRLLAETHYHLGLAYQYSSKHEEAISHFTQSIGVIEKRMDVLTKQLEASVGELVDEVKKEMDELKDLLPDIKEKIEDSKEAQKNATVTEKALKETLVGGSSGFSKENGSTSSSSAVEKSGDSTVPVTNCVSDISHLVRKKRKTEEESPLKDKDAKKSKQEPVANGAGNGDAVVPTNEEAEKAEEASMETATVESTA
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.
Subcellular Localization:
Nucleus.
Sequence:
MEEDTGIDEAKTYTVEKSEKVEPEKDGLSQFRDEEKSLGADMEDLHDETVRETLGKDQVQGVRENSSVEPNVEDVLEVNETDSVKETVVSAIVPVDEVEENRQVETSPSLAASSDSLTVTPCLSLDPATASTAQDLPLVSVPTKQEQRSDSPVVNRLSVTPVPRTPARDGYNWRKYGQKQVKSPKGSRSYYRCTYTECCAKKIECSNDSGNVVEIVNKGLHTHEPPRKTSFSPREIRVTTAIRPVSEDDTVVEELSIVPSGSDPSASTKEYICESQTLVDRKRHCENEAVEEPEPKRRLKKDNSQSSDSVSKPGKKNKFVVHAAGDVGICGDGYRWRKYGQKMVKGNPHPRNYYRCTSAGCPVRKHIETAVENTKAVIITYKGVHNHDMPVPKKRHGPPSSMLVAAAAPTSMRTRTDDQVNIPTSSQCSVGRESEKQSKEALDVGGEKVMESARTLLSIGFEIKQC