lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
RadD contains helicase motifs, suggesting it may be a helicase, although that activity has not been observed (Probable). In combination with RadA is important in repair of double-strand DNA breaks (DSB). Has DNA-independent ATPase activity that is stimulated by single-stranded DNA-binding protein SSB. ATPase is stimulated by a peptide with the last 10 residues of SSB, but not when the peptide's last Phe residue is missing. Binds ssDNA; binding is slightly better in the presence of nucleotides. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds to DNA structures with 3 branches that resemble replication forks.
Domain:
The C-terminal domain (residues 356-586) is required to alleviate the deleterious effects of UV or ciprofloxacin (CFX) treatment in a double radA-radD mutant; its effect on ionising irradiation (IR) survival in the single radD mutant were not reported. Crystals have 4 domains; helicase ATP-binding (residues 7-185), helicase C-terminal (residues 187-365), a zinc finger domain (residues 376-425) and the C-terminal domain (429-574).
Sequence:
MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAELARLARGRVLVLAHVKELVAQNHAKYQALGLEADIFAAGLKRKESHGKVVFGSVQSVARNLDAFQGEFSLLIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLGKGWIYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQYDFSRLQAQSNGLFSEADLNRELKKQQRITPHIISQIMEFAATRKGVMIFAATVEHAKEIVGLLPAEDAALITGDTPGAERDVLIENFKAQRFRYLVNVAVLTTGFDAPHVDLIAILRPTESVSLYQQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANTFWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRCRECDTVLVDPDDMLKAALRLKDALVLRCSGMSLQHGHDEKGEWLKITYYDEDGADVSERFRLQTPAQRTAFEQLFIRPHTRTPGIPLRWITAADILAQQALLRHPDFVVARMKGQYWQVREKVFDYEGRFRLAHELRG
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MVKKLPPKTIAEFRRSAETENFQIPEKPENRKCTDLGYLIFFLLVVLITTIFVACSSLGTNYNRFLNGYDKCGDTCGTSNLAVKTVQCSGKDLTNKPFMTFKYANRTNDSKSKRDILPDICDNKCDPPKRLVFHRCIPDLNKTSYRKTTIAFAEFRNDLKLAINTIIIPMAIIGLVVSLIFLHGLRYSPKITITATITSALICLFCFTSYIWYWFARNLDEKKLIYIGIVSSCAIFLQSIFICYFHDRYSLIIKMFREATQVIFAMPSLIFVPLGFVAILAVVTASIVFLGALISTNQYLSEIPDHPSVYEYRDTRLAEGALACIVVFGIWTFALANGCQCMIVSGAISTYYFTRDKSTLQKPVRASFYVLMRYHLGTVALGSLCITFFSIARLCTEFLAKRCKNKWSLRGLSRVLSWIEGAAEYLSKRAYIQTAMHGEPLFRSGLRGARLLWANFLDNIVLYGVGNFIVVCITLSAVFLGTIFAIIVYKTAGLKVSYFWTIVAIGAGISGTIIYFFTQVLNVAVETIFICFCEDKLLHSANNKDYFMSEELKTLIETAKKAARRQEAD
The following text describes a protein:
Function:
Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MRFRWKFFGSLLCVTGLLLVLYRQLGNVPQPPPGPASAQGSPSLTATSGYFRALEDHVPRRDARQGGKKKTNWNNVRAPEQKPKPPMPEEWMHLAVVACGDRLEETVTMLKSAVLFSFKKIKFHIFAEDSLKSDFQMKLEIWPQQISRKIEYKIYPITFPGGNTQEWKKLFKPCAAQRLFLPMLLQDVDSLLYVDTDVLFLRPLDHVWAFLRRFNDTQLAAMAPEHEISKIGWYSRFARHPFYGTTGVNSGVMLMNLTRIRNQHFKHSPQLWMQGWVALWKSVGLKNNMIPAGLTWEEMLHPLYQKYKNYITWGDQDLLNIIFYFNPEMLYVFPCHWNYRPDHCMYGSNCKAAEEEGVSILHGNRGVYHDEKQPAFKAFYEVIRDYTFDDNLFQSMYFPLQSKFLESVHTLCGRIPQVFLKQIEKTMKMMYERRVVVHIRSDV
The following text describes a protein:
Function:
Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.
Subcellular Localization:
Cytoplasm.
Sequence:
MDNTTEKKEPTKVPRRRFVGKRKTDGKTITTVKADGNEVVRQTKSRVHVGRSLNHIPDDIMEDEELNEAIKLLPQNYNFEIHKTVWNIRKHGAKRVALQMPEGLLIYSLLISDILEQFCNVETVVMGDVSYGACCIDDFTARALDCDFIVHYAHSCLVPIDITEIKVLYVFVTIAIDETHVIKTLQKNFPKGSRLATFGTIQFNPTVHSIKDTLLNDKEHMLYIVTPQIKPLSRGEVLGCTSERLDKNQFDAMVFIGDGRFHLESSMIHNPEIPAFKYDPYNRKFTRERYDQKQLVQVRGEALQVAQKGKVFGLILGALGRQGNVDTVRNLEEKLIKAGKTVVKIILSEIFPQKLAKFDKIDVFVQVACPRLSIDWGYAFPKPLLTPYEANVLLNHDVMFSEEYYPMDYYETNGYGRGRIPEHALVKN
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MEGGVSSAKSILEKPLKLLTEEDISQLTREDCRKFLKEKGMRRPSWNKSQAIQQVLSLKALFEPGDDSGAGILRKILVSHPPIPSRVTTPSTEPSNELGACGQIPFQEDDGPCLRRDSPRSAEFSGGSAHYLADKDSLKTLSPSRSPAETSALAGQMTIFYSGKVNVYDGVPPEKARSIMHFAANPIDFPDSGVFPSSRMISRPVSKEKMVEHPHYGLEKANASRDSDAEGQANRKVSLQRYREKRNERLFKTKKAPGVGSSSLEMYLNRSQPLMNAAAYSQNPSGGTGGEHQSPQNQTRSPNFSVDLNCDLNSEDI
The following text describes a protein:
Function:
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Subcellular Localization:
Nucleus.
Sequence:
MVLHQRLKSEWSYIILEVVGGTTPIDEIDDISLRHLITLALNQSFGIFGSAIPIDFLHRQSKFLYLRCHKEDKKKVLVALGSYVREPEQIRLMVLHASDFPCQAVPFS
The following text describes a protein:
Function:
Has antibacterial activity against Gram-positive bacteria. No activity against S.aureus. Does not appear to have chitinase activity.
Subcellular Localization:
Cytoplasmic granule.
Sequence:
MFALFLCIALASAKLGIDVSQPTSTSSFTCLRNKGFTTMVIVRAWKSTGSFDTNAPQTLKNANAAGFSIENSDVYYYPCISCGNMAGQVRTFWQKVGQYSLKVKRVWFDIEGTWTSSVSTNQNYLMQMMNEARAIGIVHGIYGSKYYWGNLFGSSYKYAYASSTPLWYPHYDNSPSFSDFSSFGGWTSPSMKQYRGDVSVCSAGVDYNYKP
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
AMSLVTTLYNNILRRSSTYALAIVAGAFFFERGFDLASEHLYSEINKGKLWKDIKEKYTPAE
The following text describes a protein:
Function:
Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAQAPPMSPSLSPTRTRCLNIVLCLLPFLVTFAHVFLSPYTKVEESFTLHAVHDVLAYGFNPHNLQLWDHVTFPGAVPRSFIPPALLGILAYPFSVVSVASGAIKTKFGVQILIRLVLASFFSYSFNKLACSLQKAFNVSVRVWFTLLSLSSFHIPYYAGRTLPNFMALPGVLWSISHIMTAQIATSEADRIASLRKAVIALTALATIVRLELALFVIPLALSLLINRQVGFGQVLKWGILGGVGSLSISSAVDYHLWLPTLSHPSFPFKSHFQLFWPELSGLIYNAVEGHSAEWGVMPWHYYLSGSLPKLLAGNSLLVGIATGGWLLDKMGLDMMAKKAGGWDRLTGVRGVNKVMKVWALSVVTVIGALSFLGHKEWRFILPVLPILHIISALSASSLWSLRPSKLRNLMRLFVLVALGLNSLATIATTFLSVGNYPGGEVWKVMEDIPGLQRQNASIYFPSYPLQTGATLFTFVHAHSVNGTGRGLGPWSAFPETKEPRWIYNKSEDKMMENPIRVWESGIDFVVTGDYDQFLALPDKWVEVASVEGLDSVGRAPGTYRVQAKWDRKLAVLQRRENIQR
The following text describes a protein:
Function:
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSTKAYVLALAGCTNSGKSTLAKEFQRFFGAGETTIINQDEFYKTENEVEKIYHPDAEHLTDEGYYWSFDEKEAINIDQFRQRILNESKVYKNVIIDGNMITEMDEIVDLCDRIVVMTLDFKTCKRRREARTDYVPADTPGYFVNVAFPAYVRHLERARQRSRTDSRLTFIDVSESKFDDKNKSIVNFRQQILDDHIKLTDEVIDVKVVDQLVSHPSCGAISTFNGVTRDNHGGRDVSNLSYDCHDLMAYKKLRGICAEIRAEYPDVKKIAIFHRLGKVDIGESSVIISTSSPHRKTAIQATEKCIDLLKEHAPIFKYEEYSNGEVDGVWKSNIEDSKQ
The following text describes a protein:
Function:
Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity.
Subcellular Localization:
Nucleus.
Sequence:
MKCLVTGSNVKVLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQYQAATPGQDQLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNDRSSRLVVQLHCKYGVRKTHNLSFQDCESLQAVFDPALCPHVLRAPARVLVEAVLPFPPALAEVTLGIGHGRRVILRSYQEEEAEPGFLLLLSPPDSAIKAMVTEMSIGEEDFQQLQAQEGVAITFCLKEFRVRFLPCTHCPVHLSSLPSLHALLLPCQGLLSFAESANLSLSIHFDAPGRPAIFAIEDSLLDGHFVLATLSESDSHPQTLHAQEELQRPEPGPQAHSTPHLDLDDFAVDDMDSYMIAMETTTGSEGSRALPSISLSPGLQRPCSSSPHSEEEDDDMEPSTVPGTPPPKKFRSLFFGSILAPAHSPQGPSPVLAEDSEGEG
The following text describes a protein:
Function:
Probably involved in the activation of fatty acids to acyl-carrier-protein prior to fatty acid elongation in plastids. Acts on medium- to long-chain fatty acids.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MQIRLKPDYSFFIASSSTMASTSSLGPSTLLSYGSPSRQFPDFGFRLISGHESVRIPSFRRFRVHCESKEKEVKPSSPFLESSSFSGDAALRSSEWKAVPDIWRSSAEKYGDRVALVDPYHDPPLKLTYKQLEQEILDFAEGLRVLGVKADEKIALFADNSCRWLVSDQGIMATGAVNVVRGSRSSVEELLQIYRHSESVAIVVDNPEFFNRIAESFTSKASLRFLILLWGEKSSLVTQGMQIPVYSYAEIINQGQESRAKLSASNDTRSYRNQFIDSDDTAAIMYTSGTTGNPKGVMLTHRNLLHQIKHLSKYVPAQAGDKFLSMLPSWHAYERASEYFIFTCGVEQMYTSIRYLKDDLKRYQPNYIVSVPLVYETLYSGIQKQISASSAGRKFLALTLIKVSMAYMEMKRIYEGMCLTKEQKPPMYIVAFVDWLWARVIAALLWPLHMLAKKLIYKKIHSSIGISKAGISGGGSLPIHVDKFFEAIGVILQNGYGLTETSPVVCARTLSCNVLGSAGHPMHGTEFKIVDPETNNVLPPGSKGIIKVRGPQVMKGYYKNPSTTKQVLNESGWFNTGDTGWIAPHHSKGRSRHCGGVIVLEGRAKDTIVLSTGENVEPLEIEEAAMRSRVIEQIVVIGQDRRRLGAIIIPNKEEAQRVDPETSKETLKSLVYQELRKWTSECSFQVGPVLIVDDPFTIDNGLMTPTMKIRRDMVVAKYKEEIDQLYS
The following text describes a protein:
Function:
Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
Subcellular Localization:
Nucleus.
Sequence:
MSVASFAGPKDTATESVSNTSRKRNSPSVRISKRKLKAPINSDDEGDLESNHSQSTLKENNGTPAPITVQLSLNKPTSLACSINITTSAPLNSPPRSVLTPSSVSSPPKGVLTPPSENLPSPNTSSNKNVSPKQTPKKRLFDESNKTNTPSTSKICVLENRVIVTSPLKKSPKNEVKDETKKLNYDVLKVMREFFINVLKYSHLKCLLSKSDQDMLYNFYNIEKDYQYTCVKLFLWKQQWYNIFKYVGGIGLKMSDNDVTAMYKCLEEKHFVDTNYMAEETVTLLNLLSVADLRAILAQFKLPTAGPRESLIDKLLRNCKTQVTLTCTKSTEDLLRERIKERMGYCVRLSTNLNRCLRYVFLLNTFTNFSLTVPQDYFKNVTYFNTVFPSCKVETFHIFYTPGEFSKYADAVDLNRELEEAIEKKNNPNILVLCQRAFNLLKQANEEAKNDMREPHLERFTPNAQYIRIITQGLKHIKRHNFGEVQIWLEYLITQKYCKHKRGDWYCELALIYTEYLKDYEKAAKLIIKAFKEEKEFLTDIQLQALAHRGRLTNRKTYNLPSLYHDEIAALSPPACDRDWPQEVLDCESLKSQKSGQKRKYVHRCANGDVEYLSVEQKALKHYETMGFPSGLHCEGSVVIAAFYLLFWDIIYEEYVRGTFISSVQSAPLDMHTPYFYKNRERSIQKRLDEIRDKWKNIELRTKLSRAWDLHSHENSVIEAAVPKSDHIFDVIMCIGRPVLAKIFERLVQNFKVYQSGFPDLIVWNVEEGRAKFVEVKGENDKLSIKQKLWLNYLCDSGASVEVCRVEPKATKKQFKRSVAAACH
The following text describes a protein:
Function:
Involved in sex determination and dosage compensation. Required for proper expression of Sxl in embryonic somatic cells. Also has an essential function in the yolk nuclei. Involved in endoderm migration and midgut formation.
Subcellular Localization:
Nucleus.
Sequence:
MERSHLYLPTLSYAAMGHVYAPYRGSSSPALSTASSTSSKPEQIEELVSQQLHHLKMHYADEEQRYVDQMLLENPIVVERRAPPPLKTELAMDCRGSGSGSGSGSGSDVKDAQRQRAESCRKSRYNNKIKKAKLRFRHKFVSGQLKKSAVMLDTMRDVIAQAERQLLERGYPAATLERMRATFGLEMEQ
The following text describes a protein:
Function:
Implicated in cellular adhesion to substrate or phagocytic particles.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MNRILTLFILFISLFIVCEATHFRFGTMSWMPMGSHNTIKFSSNYAFRIGFFKKFNKGCNVGDVVKVGDLDLGDDKTKVDVNLVVTSVNQADDWFTGEFSYTHTYNPIKLGGKAVTYKVVFTDCCRIKSLLNNAEGSWYISTSVVVDPNQGSDVSTFNRSPVSGMVPIITLNRDKNNQFLIAASDPNGDTLTYSLSNAYTMNQPSGLSIDSSKGIVSFKPTVSGFYSTQIMIKDTKGAYVVVDFLINSVIEPGVCHPSCSNGGNTCNGNSGCKSCKGTDSNGNTCSSFPPVFVYPPTPTDGSLLAYEVNKTNSFSIQCKTEEKSKTVFIQPANIPLAATLTSSDQNKQVSTLTYSMLPQLKHIGVYVISAYCTDNKGLVSTITSFSISVEKPICGHGTNKPGGGCNCETGWDPEKNCYECLKGHYGEKCDPVDPCVNGESNEGSQGNGKCTCYYGWEGKNCDIKVNQVCNANKENVVLDSSVAKSSYINPNFAQVYLNTDPSKQALTLSSKLSIPETIDKFEVLVLVDSQPSIVEYWDNFKKYSSDLTKNLQDISETVSIGLGLFSDAKTNGYSFVLKKSIGNGLSGLDDKDKAPASSYSTKNSLIALTSAAEFPAGWSTGSIKIIVLLTDNDYSATAQEVSKFTSTLISKSILPVVVSFNDNQNWDTLFKNQGFGSTKKTSNAKGNDWVSVATSAIKDVLSKAVVKAIDDTKGFLTLPSATTISIEDSKDYTIPIQIKYPQGQSDIPQNPSVSYSVVGFGITRIVINYNSAPTALGYSIETKQNVNYNFKLSGSDVDGNTLTIKFKTIPAASVGVIQADGVTIEQGDSFSIEKTFTFKPATNYYTKSTNDKFTFVANDGCLDSNEATVEIKITHVNQAPSCSSLSGSAISVTGLNTPKSFSLQGSDIETDSNLKIVFGDLTAISAYGNIKSGSNVVSTGSSVQLSSGSASLTFTQTKDIANDKEITVDFKVNDGSLDSSSSCSFKVKFVHFNKPPVAFAVTPLTIRQNSELKITISASDSDSDSVIFTLDDLKLGGGDSFFKCDDRSQLTAPFTTQPVSISGGVASFSEICYSSPLVNANSYASLVFFANDGQLSSDKFKVLININGDRPNAPPVVNQIPNFTMNEDDISNELVIDGIDPDELDQGKLKGIIIQKPTNGVILVKSGSSTSEAPIIGNAPYKIFYKPNPLYYGTDSFSYTVEDSMGERDATPKTTQITVQHVNHAPTLSIDPYDFTSQTSEKTLELTPKDIDLIDTVFHCTIVKLPATAIIKTSAGKVIDTVPTDLSDNKYIITSNNNIYNDFSDSFDAKCYDSSNAVSNIATGPITFRYINVPPKAESSDETLNQDSSVSFSVKATDLEDNSNVRAVIRSLPAKGTLTIKSTGKAAEISSTYAIDDFVYTPVAGYSNWDKPGHVGPADSFNFVAKDSKNDISSNIGTVSFFIEPRNPPTYEGLAVLYTKENTDLPFSISGIVGNGGSNVFLRIKSIVSRGSLYATHCMGTEGCMSEPNPVDININFTSQPYTFSFTPIEYENGDNYAIIEFVLYDKFNGQEVESQKYTIIINVIPVNQAPEVILIEHTLSTLPNNVIAFDKFKTVKMETNSYVIIKYDGTDIDDPKEKLKSYIVSPPLRGLLYVYDKDAKDGLGKLIKKDDTFVPVAQDGFWYIVFVPTPGSSGDGYVRIPISMVDFLGDISVPVTVAVDVSKKNIPPFITIENKNYTSLANTSIVVTGVSFDDPDSKYNDVELILSLVNKDGDLVSNKIATFSLSQQSKAKCTKHSEFAQFTCRSNKKTLNALISTMYVNHQGGGSYRLKVFVNDLGYSSPASIRDKNHMTATDYVELDVTKPEVTTTKENNNKTVLTGAIAGAAAGAGLLAAGAWFLLKKSAPPTDAFFGEGAFADGAVSTNPMYEESGRSAINPLYEASSENL
The following text describes a protein:
Function:
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
Sequence:
MALSSLRSFPLPRSFDEEMTEEEWRKSSCARHKKSVEKRVKMVEFSMNATREEERPEEGRKKLLLRSPPPAACYCEECAGPSSKSKPRAMANSRAGEVALKSGSSPKCKWIFTKEEMKNTASLREGLDEFKELQLRQQSTKFIQLLGDRLNQNLRDHRGKITQLCMCAAMIHLHRFFYFHSFTFFDYRDVAAACLFMSGKSEECPRKIDHIVRAWWNEKFPGIKIDQEKYDNAMGLLVAIESLILQTIAFDLKVALPHPLVLKAIDNRKITKVVYFFSTDVLCVTSWGIRYSAEAIAVACIHIVCTWANFENGTVSLIPTHPGPPTSRTTGLQMPPSEGGTKWYHKMDPTMTEDQLNEMMIEFIKVYKTCKNELAITKFIKKGEIRNPISDADDRATPPALMADDMRLPPPPPPPLSLASKKVDINAYKERRATEGGSASGHHGQHSQQPQQRRSFMPELAKGVTASMPGFVPPKQEPPADVKPDRAGLDWTRESGDRNQTERKPECEFFVSKQSHARTRTGPPRSSGRPDHPAEKPSNGSSSQQLQQSSRSSSGGGGQQYPYMHQQQPSGSGDRGMERSMMSGDRGRDGDRERSEKRKRESSSSNLNSDKRARPDMAMQQGGPPPQQQRGHSMMPQQQQVQQPQHGYNSVPPPLMQQTQPHFGSSSKVGEASLGFFRRH
The following text describes a protein:
Function:
Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).
Sequence:
MVVPREPAATAQVSVGGFRAGLSARGLADHLESVAGRVWRCRVKASCAPPDTYPDFQFQRRRRLLPAADASGRAAPSRSPSYTPRRRRAPDGDYDDDDAAFRGAPSPCRPAAPPHAFVHFAHPEAARRAAAGSELIVRAQNGNGSARAAARHRDTAEPFRFAGSRVELGNLWAPDAFAVAWRAPEPEDADAAAPAGGLVFEVDPSDGACRLVFSCDAAFALPGARGAPAVLRCDVKLEFSFLEIAEVMAFQADDSLLLRLSAAPLLYYRTAADDVHQPVPFHLPDDDDDPWIRTTDITPSGAIARCWVYRVSFRAWCWPKMKDALAYMKRQEVPVVFCDIGRRGLNVNDEPAFGQPTEDLFFCVEREGLRFPVLFLVNVLVHKGIVNEHQLTSEFFGLLEKEDDDVNVAALTELLGEKLQVFYLCRRLKNAQDRAAKNNRLLHLHGSKKVTGDHNAVVRSMMITPTRAYCLPPQVELSNRVIRHYHRVADRFLRVTFMDEGMQPLNINALNFCVAPIVKDMMSNSPQQKTTVHRRVQTILTKGFCMCGRKYSFLAFSSNQLRKRSAWFFAEDGTTSTASIRQWMGQFPSNNVAKHAARMGQCFTSTYATVTMQPDEVNEFLEDVKRNGYNFSDGIGKITPGLAMEVAKRLPLMHNYPPSAYQIRYAGFKGVLAVWPGKNDGIQISLRPSMRKFESTHLVLEVVSWTKFQPAYLNRQIITLLTSLGVPDAIFWQMQEAMLHNLDRILSDRDVAYQVVTNCCSEHATIPALMLSAGFTPATEPHLKAMLLAIRSSQLQGLLEKTKIFVPKGRWLMGCLDELGILEQGQCFIRASVPSLNKYFVKHGSRISLANKSAEVIVGTIVMAKNPCLHPGDVRILEAVDVPELHHLVDCLVFPKKGKRPHPNEASGSDLDGDVYFVTWDKNLVPPRKKSWPPMDYSPVEAKQLPRRVRQHDIVDFFLKNMISEILGLISNAHVVHADYSKYGAMDDKCIQLAELAATAVDFPKTGKMVTMPPSLRPQEYPDFMGKEDDISYKSEKILGKLYRSIQQYNLGRSLEDSIRNDVPYDTKLEVPGASHFLADAWQCKCSYESQLNGLLNQYGVRTEAEVVTGEIYSLTERNKKKKNEIKERLKHAHSKLHQEFRNIFESIGADHGEISDDKKNLVYEMKASAWYQVTYHPYWIQFSRKMTEFDGKEMPARLSFAWIAVDYLARIKMRCRGE
The following text describes a protein:
Function:
Transcriptional regulator. Binds to the 5'-flanking critical region of the SCARF1 promoter.
Subcellular Localization:
Nucleus.
Sequence:
MEVAVPVKQEAEGLALDSPWHRFRRFHLGDAPGPREALGLLRALCRDWLRPEVHTKEQMLELLVLEQFLSALPADTQAWVCSRQPQSGEEAVALLEELWGPAASPDGSSATRVPQDVTQGPGATGGKEDSGMIPLAGTAPGAEGPAPGDSQAVRPYKQEPSSPPLAPGLPAFLAAPGTTSCPECGKTSLKPAHLLRHRQSHSGEKPHACPECGKAFRRKEHLRRHRDTHPGSPGSPGPALRPLPAREKPHACCECGKTFYWREHLVRHRKTHSGARPFACWECGKGFGRREHVLRHQRIHGRAAASAQGAVAPGPDGGGPFPPWPLG
The following text describes a protein:
Function:
Regulatory protein for the mmsAB operon. Activates the transcription of the mmsAB genes.
Sequence:
MDYIAEPATDMSHTSDWPLPADSLRLPIPAALLEKLAVHPLSRDLYPTSLGHYRRARDHRMSRERHDEHLLIYCSEGQGLLRVREGEAWREYRVGSGDLLWLPPGMAHDYAADDRQPWTIFWTHLRGDSATWLQHSAGYRDTPLRHWGLQHALLGGFEQLLEVRHSGYRFQHFLLAASRLRSLLCQLPLLRPLREGSLDLDGLHAYMREHLHARLELERLAAFCNLSKFHFVSRYKAITGRTPIQHFLHLKIEYACQLLDSSDQSVARVGQAVGYDDSYYFSRLFSKVMGLSPSAYRQRVRQGEGGA
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSTLRGLKGFISQRLTAAVEDILGHLEKTILEYEEETERRHRDLLDVVLTAEMKQQEDADIQEPLAGKQSPSTQERRSHPEQENPNSALLNIKQEQEEISISELRSSPVFVKTEDEDKPQFPQVEEPIIILDEEDSEGPEPQTVLKTEAKADLCSTTQEPHSDVNINNALNTIGLNSLNLFRCSECGKTYSSQSYLKLHTQYHAERPYRCPVCRKCFTWRGRLQKHMRTHTGEKPFKCTVCCKRFSESGNLKVHMRIHTGEKPFSCSFCGKSYAQRGNLKMHMAMHRGETTVSSSRLQHSQTESRTSLRGPEETAHSDPHPRFQASPGLQHVTGNGGVPANCWRATACKKSYSCSECGKRFGFKGQLASHMRAHTGEKPFRCPVCWKCFSWNACLQKHMKIHTGEKPYRCTVCGKGFIESGNLKVHMRIHTGEKPFNCSECGKRYRQKGSLTKHMDVHRELK
The following text describes a protein:
Function:
Probably involved in membrane trafficking.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein.
Sequence:
MKIATLKTWYMLANWFRYSLVKSGAVIDNNNWPSFYPLVHHDIAGDIPIHLQRIQYVAYATLLAGVYIFFSIIYFLLGPPGAFYFWYRPLYRAFRKNNGMNFGCFFFNYAYHIVFFGFAAIGPRILFSGLHFAYIMSFIGFGFFATELVLSIWVMQKVYRVFRGNDKATTAPISIAL
The following text describes a protein:
Function:
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Subcellular Localization:
Nucleus.
Sequence:
MGAEISYNELKHLSEECSIDQLTCEEEDTKHFPTKLPENINSSTKLPGTFITNESNHFAINKFIQEMEKQKNPSQSCIGNKRSYYPRLEFPVSPYPPDLKPGSDFVASILIYRPVEFKFFHAKNASEKLRFSHEIVVLGRNTLTELRDTIMCSSDFGLCKEVENTSADLKPLANARNIYPSGFIFIDNVFYNDFRDPNSIDYSFPIIEWAKEKQIKNLSSENMENVRIESLTPRFGYPYLYMHQGDCEHLFIFADARLLNSSDCLHSQFYPHVLKINRNINRMCFMCSVSFAKWIVVDSDRLPQHKVFMCTDCCNSYNYVNGEKLGSFKLYPYYEKHVVV
The following text describes a protein:
Function:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MEDRIQFDINESLKYYLSDPASVPTNDADPELLDCESDLEHLTPALIDNVLNPIVDAVAESPEALARQSFFDSLQFLLKCAMAPSSFSEFPGHGGTLSELLNSCRYSSFLPTKSLSKLLDLIVSGLSLETDIIHGDLEAEEQDAIQHHKQLLEMYGFLLQWALSAVEVKAAEKPAEAAPARRGAGKSGRSKTSNRDGTWDWTAQIQISMETMCKVMKLKLSRIFMTTSDRDTFINLFTRAIYLILESEQRVKSLAIRMHAFKVLCIASYTLRCAVVEVCGNLIADLSRQEERSENYKTQINAFFDVLEERFLDVNPYCRCRAIQVYMRICDLEQKFPKRRQAVAELAARSLEDKSSNVRRNAIKLLAKLVSTHPFSVMHGGQLSYKEWAARLENVDAELNALRPPETPGFDGGEASHVDSELLDDATQIPEDSPSKAPRMTDAEKAAAIQRAAEQAATSELLARLQLTRKYYNEAIRFIEVLHSASVVVSQLLSSRNKSEVIEAMDFFVVLDAYKVETARSGIRRMLRLIWTKGNSDEGKGVQTHLIDCYKGLFFDAPDSFGPNDAANYVARNIISLTFGSTPAELTCLEQLLSTMMKAGHISDAVIAKLWQVYGVQRKEISKTQRRGAIIILGMLALADPEVVIKETEVMLRIGLGNIGRSDLLLAKYTCIALKRMVPGRQAKSKDAGIPKLANDHPVLSKLAAMVEIVSDSKEWYGVAEQAIGAIYTLSKHPDVLCSDILKRKTRAVFQPQLQRPSSTASGDEEEQRPGTASTDGQGPRPRTSSAALSQLLFIVGHIAIKQIVHLELCELDFKRRKAEQEKHKAANTAAHKDNQTGEDDELDLIGGTTEDDFTEAMSHIRERELLYGENSLLSNFGPLVAEICSNSNAYPDRNLQAAATLCMAKLMCVSAEYCEKNLPLLITIMERSEDPTVRSNAVIALGDMAVCFNHLIDENTDFLYRRLNDDDVSVKRTCLMTLTFLILAGQVKVKGQLGEMAKCLEDDDKRIADLARMFFTELATKDNAVYNHFVDMFSLLSAERNLEETALRRIVKFLIGFVEKEKHARQLAEKLAARLPRCETERQWNDVAYALSLLPHKNEDITKTISAGFNKVVTAKS
The following text describes a protein:
Function:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Sequence:
MYNSQAQPDYYGGYENYTQQIDTEVANVVGDVGASFPTSMYNPQAQTYYYGGPEGADAVGNVGASFPANMYNPQAQPYHYGGTYYNPQAQPHYHGGTYNNLHAQPYYDAQAQPYYYGGTEGADAVGNVGASFPANMDNSQAQSFYYGGYGNPSGTFVTYTQHVGIEGTNAVGNVSGTDTQHVGIEGAIAVGNVGASYPISMYNPQAQMSGSAAAYSEEHPLVFNAGNGYGQYMPNGPYYPSAMPAYVGGNVQGVSYPSTENNNTIRERGNASFGRSNGTHGFLRRQSRRPWTNRSNNRAIQQHSVAESGGANCSLGVDRKLYNSPEFVTEYDDGKIFIIKSYSEANVHKSIKYGVWSSTSAGNKKLNSAYIEAQKKGHSSPIFLFFSVNASGRFCGVAEMIGPVDFEKSVDYWNKDKWTGQFPVKWHIVKDVPSFRFRHIILENNDNKPVTNSRDTQEVKLEQGLEMLSIFKTHEYKESILDAFEFYDKREAALRRRKARQQETRTTTRNRISKRFVQVVKFKGETSNVGISTDKTSSSNGVGSSPTPKDV
The following text describes a protein:
Function:
Required for mesoderm development, including specification of muscle and coelomocyte precursors.
Subcellular Localization:
Nucleus. Note=Nuclear localization most obvious in the 8 embryonic cells derived from the MS blastomere.
Sequence:
MSSSNYNINNGGDYYPLSSSNLNSTSAITNATVMEYSTMPSSSPGSMSSSPAYPAAYQAPSPCYVADPNQLYYQQQLAHNGNDMLVQAHAQAYQAQCFAWFQQQYSQLSPSSFPHPMVAHHAGFIPPPPSFLHHQHQQHPRAPSEKRRGARTPFSDSQLYALRTRFEQCDTIKVDERRKLGAVIGLSPEQIKIWFQNRRFKLRKEKYKQIKQDAVQQQKSAKEEAEEDQKHVIS
The following text describes a protein:
Function:
Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.
Sequence:
MAGEPNKAAIPCFFPSFACKQLMGEDTLEWHNDEDNDERRERSYITHALPGSLSPSSSSSSVSKPSSSTSSITLASSADPRRLSVVSRPPTAMDPYKYRPSSAHDSSFWTTNSGAPVWNNNASLTVGTRGPVLLEDYHLLEKIANFDRERIPERVVHARGASAKGFFEVTHDISQLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFVRDGMKFPDMVHALKPNPKSHIQENWRIVDFFSHHPESLHMFSFLFDDVGVPQDYRHMEGFGVNTYTLLNESGKAHYVKFHWKPTCGVKSLLEEEAIRVGGSNHSHATKDLYDSIAAGNYPEWQLYIQVIDPDHEDKFDFDPLDVTKIWPEDIVPLQPVGRLVLNKNIDNFFAENEQLAFCPAIVVPGVYYSDDKLLQSRIFSYADTQRHRLGPNYLQLPVNAPKCTHHNNHHEGLMNFMHRDEEVNYFPSRFDSVRHAEKFPIPPPVLNGKRDRCMIEKENNFKQPGERYRSWAPDRQERFIGRWVEALSDPRVTQEIRSIWISYWTQADKSLGQKIASCLNVRPSM