lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.
Subcellular Localization:
Secreted, cell wall. Secreted, extracellular space, apoplast.
Sequence:
MASSLPSSSCWHSMVLVAMLVVVVVDQMAMAYMYDDIEIVWGDDHSFFYMDDAGDDEILALCLDQTHGSGFHSKEAYLYARFDVDLMLVPDNSAGTVTTLYLMPEDVPWDYHDEVDLEFLGNVTGEPYTLHTNIFANGVGNREEQFRLWFDPAAGFHTYSIDWNPKRITILVDGVPIRSFRNKEEHGVPFPTWQKMRLHGSLWNADDWATQGGRVKTDWSEAPFFAHYRNLRVSWCRPPPGVAWCGDEPPGSTWFDRGLDAAALRRARDAHMIYDYCKDVQRYRWSGLPKECVVE
The following text describes a protein:
Function:
Has a role in spore morphogenesis. Involved in the assembly of the forespore membrane.
Subcellular Localization:
Prospore membrane; Peripheral membrane protein. Note=Associated with forespore membrane.
Sequence:
MGILSVIRIFIYCLIRLFSFNSRKRNSSIDELERGEINAFACDKQNTPSPNSECRPLTPLNSPFRRTVEGDTANLQAPSPTACPSFDSASSIKSSKEDIACRKLSTERFFYSPNGIDEMKKQQQFKKIPTVSITEVEPAFIPSNMEQALFSEEPFVIQDDLSHQINLDDNRKFSRIQKNKLDPLITVNLVPIVNGENCFNFYETQMETNFLSPEFIKKPSMVDHKRDSEINAVTAVSADGSFSPLTETLSSTISTLSNDSLDGLSSQKNEFTGFNSNSEWIPNDTVDYICNSDASSVVSNLSDFEDCFDQFGVYDKEYEKKIEKTKRNFPKFQSSATYPPFSAHHQARRNNPQGFRNVKKRFQLFKDDCTALTDSDFLDALPFFNARVIIALYVEWRLRVYETMIIKGEESLKNLQRARDGPHNKLWLGVFGNKDTIKKLSNYDRRAISNPYVSNHLNFNVRRVKSDTVYIPTILQLLRSSTQLMTEQAFVASSNLKSTKGLRETRLIQKYKVKGDFEYVYAALYYAAFTQESTLKAVTIDDILSEDELEDWWYLNLRYTSFITPQLCFEFLDKEADSCRDRLTEVKSEPPKAVIYEEPLNKLSRFSSDRLFTSHELVAIAELISLNEPPLESGKKFYYEEFQKACQKKRDDYRYSPEIEFKAAFREKFLQSNEKVPFPRPGEIYEKRCDYFSKYACQNIFISKPLKRSGSIYEVFSDGIGRVIYGSVLDYEATRNNILLHFGFEIHCAPSEEELIEREEAFKDFHNMLSFKYSANEIYEFCGTHSRAEVHKNEVLKRMAYYLIDENKEISILRRILSLRIVEPTTSFTRYEYDLWRTFYPDVLYLNYSKSGRIPTGSPYIMNGQWRKDLCVSTPPMVDINSALFPHWFKLSASNLFAGAEHAGLNRQKPDKIDLDLYEPLPENSYLVAAELRVLRALRHKNPENIPLLEKWEVRALHQLMAKIRKYYTVPTDYLSLRMDGLQAMLRKREYMSCYTFNYFDYACLMDHAYRLYEGFNNQVVNLPPRIM
The following text describes a protein:
Function:
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
Subcellular Localization:
Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle. Note=Nuclear during interphase and associates with the chromosomes and spindle apparatus during mitosis.
Sequence:
MAASLPLPASGLFRTYGAAGGGRPRRRQGLAAVQWFPPQDRKRFFSSSSSDTSSGGPSQSVVSDDPDDPDFPGSPVGQRRRRAGARLAKGRPSQIATPRRLRLRSRCPQKCSTPCGALEPPSFPNGNPGSLSPDLRVCGQPRDGGELGTSASLFSSLASPGPGFPAPEDSICTDPSTFLDAASEAPSNFHLPEASLDQAPLPCSQDAATGGGRFTRLAHQAQASLRSALFSFLDPGNPEDSELGTDGKNLQEFCHDRELVGRRLESPGLSGRGKKRTTDQDSCREIESQESVQIEYEEARGCKGGIASGKSNGPERTRLSRKRKHQGTAETSLLHHCQVTKGQKMEDGSCVTQDLTRLQNACSWTKTRASFSFHKKKIVTAVSEVCSCDTLAGSLSESLMSEYSHHPVQNRTSCALSPWHSSSMYLLTPLKTQQVTDKRTSDAEKLYGECNQVGPIPFSDYLSEEKLECCEKIGEGVFGEVFQTVTNHTPVALKIIAIEGQNLVNGAHQKTFEEILPEIIISKELSLLSDEACNRTEGFIGLNSVHCVQGSYPPLLLQAWDHYHSTKGSANDRPDFFREDQLFIVLEFEFGGIDLEQMRKKLSSIATAKSILHQITASLAVAEASLHFEHRDLHWGNVLLKKTSLKELHYTLNGKKSSIPTRGLQVNIIDYTLSRLERDGIVVFCDISRDEDLFMGQGDYQFEIYRLMRKENNNCWGEYHPYNNVLWLHYLTDKILNQMTFKSKHNTPALKRMKKQIQHFYQTMLNFSSATDLLCQHSLFK
The following text describes a protein:
Function:
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Subcellular Localization:
Secreted.
Sequence:
MKLWLFACLVACFVGAWMPVVHAQGAFEDCCLGYQHRIKWNVLRHARNYHQQEVSGSCNLRAVRFYFRQKVVCGNPEDMNVKRAMRILTARKRLVHWKSASDSQTERKKSNHMKSKVENPNSTSVRSATLGHPRMVMMPRKTNN
The following text describes a protein:
Function:
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MRRKGTKPSTACHQEEGPPPSEDGALSEGEKEQPDCEVDSAAAAETPGEELDSRSLEEILNSIPPPPPPAMASEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHTDIQSCTVEVHFQKIIDKEGDDYDVLPNSNFYVSRTAYRDNTSVYHISGKKRTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTLENEIFKKKNHICQYYIYDLQNRIAEMKTQKEKIHEDTKEITEKSNVLSNEMKAKNSAVKDIEKKLNKVTKFIEQNKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEELKSIPAKSKNVINETTTRNNSLEKEREKEEKKLKEVMDSLKQETQGLQKEKEIQEKELMGFNKSVNEARSKMEVAQSELDIYLSRHNTAVSQLSKAKDALITASETLKERKAAIKDINTKLPQAQQELKEKEKELQKLTQEEINLKSLVHDLFQKVEEAKSSLATNRSRGKVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDIAISSCCHALDYIVVDSIDTAQECVNFLKKHNIGVATFIGLDKMAVWAQKMNKIQTPENTPRLFDLVKVKNEEIRQAFYFALRDTLVANNLDQATRVAYQRDRRWRVVTLQGQIIEQSGTMTGGGSKVMRGRMGSSVVDEISVEEGLSEQEEYLCVQIKELEANVLTTAPDKKQQKLLEENVNVFKKEYDAVAEKAGKVEAEIKRLHDTIIDINNRKLKAQQNKLDTINKQLDECASAITKAQVAIKTADRNLKKAQDSVCRTEKEIKDTEKEINDLKTELKNIEDNAEEVIKNTKDAEKSLPEIQKEHRALLQELKVIQDNEHALQKDALSIKLKLEQIDGHISEHNSKIKYWQKEISKIKLHPVEDNPVETVSVLSQEDLEAIKSPDSITNQIALLEAQCREMKPNLGAIAEYKKKEELYLQRVGELDKITSERDNFRQAYEDLRKQRLNEFMAGFYVITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNITKSVAVNPKEIASKGLC
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MEVAAHVDDYNGSFRDTVWLQSFPLNAQNTQEPARRRLPQQLYIIRKQRRSGRTQVEPLAIYYVLDGTVYQAPNIHAMLTSRLKKCSYRVNKAFHGLAAGVRFSPTEGYAWDFSSKDKKEPVVPSEQLQLKLKQKYEKMEKQRENSARVDSILIQLMKKHAPEIAEKLENNAAAAAGASSAQDPAAAGAIKRENDATASTEAAKRQKVA
The following text describes a protein:
Function:
Involved in larval molting and metamorphosis. May degrade extracellular matrix (ECM) and basement membrane (BM) during the development of organs to allow degeneration and remodeling of tissues.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MPCCLWAALSLLLAVVGAGAWTPPRQPLLLTPRHRRHAQETHHLRLLGWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVIDLDLDFDEDDDLLPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGEGNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERSTDEGVELGGAKELSNYVFTMDEQCRTEFGEGFSVCRSVKVRSACSRLWCAHRAMPHVCRSKRAPPLEGTPCGQNQWCVDRVCEPMPGHSKETKVENKHTPEWGDWEEWSACNADCGYGLRTRTRKCKYRGFVSESACEGAGSQVATCWAGSSCAATRDIRSDLCHRQQSRLIPYLHANESNHCEISCVDYAGGSPTNFGALPDGTPCSYLRPFDVCFQGTCVKGQCNSSDTTCNWCPDGYCNNNTNTYTRLLGNGWTRMTMVPHEARQLSIHIATPIPLHIALRERKRDKPILELSKHSKKFDISSLQDNYLKYDPSVPQNLQIVEMDSNILDLKESFRYEGEAITAGTLLRWNQTDTDIYITSESRLQTDLMIMAIPVNPTLEDAVSVDASVNYSTPTGRTRPLEYRWSIERGPCSASCGGGVRLITAQCHRDQKCPPPRYESCNTHSCEFVWASDDWEECSSTCGSNGVQERQLFCVPSNASMLSRREFIKHSVSPVMCSSSKPPHRQPCNRIPCPVYWREQPWTPCSASCGRGVSRRPLTCPASDELLCGPKPRERRRRCRLRRCPSALRVAVQCPERDHAHYCELFTLEQLHRNCEVPPFRKYCCNACRDADRRQHRRYG
The following text describes a protein:
Function:
May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC.
Subcellular Localization:
Nucleus.
Sequence:
MAAAGGAAGRGGPGRPCPFSIDHILSSPPERSAGAARAPPPAGRQSPAEPGEPGAPEAAPCGCCCCCGPRAAPRGPPEAAAALGARLPWPLRLGPAAPSPLAAAAGGSGALPGAGGPGPQRRTRRHRTIFSEEQLQALEALFVQNQYPDVGTRERLAGRIRLREERVEVWFKNRRAKWRHQKRSATSRLLPGAKKPPKESG
The following text describes a protein:
Function:
Glycerophosphocholine acyltransferase (GPCAT) that utilizes acyl-CoA to acylate glycero-3-phosphocholine (GPC), forming lysophosphatidylcholine (LPC) (By similarity). Shows broad acyl specificities with a preference for 16:0-CoA, polyunsaturated acyl-CoA, and the hydroxylated ricinoleoyl-CoA (By similarity). Also catalyzes the acylation of glycero-3-phosphoethanolamine (GPE) with acyl-CoA (By similarity). In addition to acyl-CoA, GPCAT efficiently utilizes LPC and lysophosphatidylethanolamine (LPE) as acyl donors in the acylation of GPC (By similarity). Contributes to the maintenance of phosphatidylcholine (PC) homeostasis and might also have specific functions in acyl editing of PC, such as transferring acyl groups modified at the sn-2 position of PC to the sn-1 (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MDHLEFDENTDSEYSIFEEDNDYGLHGLDDSVGFTDLFDAPNIYRVYSWLHKHYNQKKGQLKHGVSRQKNKLQPIHKQINYETDKLKERLGKSIDKFQEQWNSGKVVRFRDKLSFALGVSTCILTALLVGMAPESMHLWYTIQLFVYLPLRYYTYQRKGYEYFIADFCYWGNILLLVYIWIFPESRRLFILSYSISYGTLAWSVVAWRNSLLFHSIDKITSLFIHFFPPLVLHTIVHLTNKSYLKDRFPAVLKVKKIDLLSSVEIASFFYALWQIWYYFFIQVGKQKQIQEGRPTSFTWLSKAYSKTKLGRAVAKLPQNLQPFVFMIIQYLYSITTMLPCSLWYNNKLYSTAFLALIFGWSVWNGASYYIDVFGRRFQKELEALRQQLAETPTNSGSSSALSR
The following text describes a protein:
Function:
Serine/threonine protein kinase that plays important roles in several processes including nuclear viral egress, viral replication or regulation of host cell cycle progression. Participates in the acquisition of tegument during virion morphogenesis in the nucleus. Redistributes the host nuclear lamina by phosphorylating cellular Lamins-A/C. Plays a role in viral DNA synthesis by phosphorylating the DNA polymerase processivity factor UL44. Stimulates host cell cycle to support viral DNA synthesis by phosphorylating host retinoblastoma/RB1 protein. Additional substrates have been identified including host EF1D or H2B. Also phosphorylates host SAMHD1 and thereby counteracts its antiviral effect by reducing its dNTP hydrolase activity.
Subcellular Localization:
Virion.
Sequence:
MSSALRSRARSASLGTTTQGWDPPPLRRPSRARRRQWMREAAQAAAQAAVQAAQAAAAQVAQAHVDEDEVVDLMTDEAGGGVTTLTTLSSVSTTTVLGHATFSACVRSDVMRDGEKEDAASDKENQRRPVVPSTSSRGSAASGDGYHGLRCRETSAMWSFEYDRDGDVTSVRRALFTGGSDPSDSVSGVRGGRKRPLRPPLVSLARTPLCRRRVGGVDAVLEENDVELRAESQDSAVASGPGRVPQPLSGSSGEESATAVEADSTSHDDVHCTCSNDQIITTSIRGLTCDPRMFLRLTHPELCELSISYLLVYVPKEDDFCHKICYAVDMSDESYRLGQGSFGEVWPLDRYRVVKVARKHSETVLTVWMSGLIRTRAAGEQQQPPSLVGTGVHRGLLTATGCCLLHNVTVHRRFHTDMFHHDQWKLACIDSYRRAFCTLADAIKFLNHQCRVCHFDITPMNVLIDVNPHNPSEIVRAALCDYSLSEPYPDYNERCVAVFQETGTARRIPNCSHRLRECYHPAFRPMPLQKLLICDPHARFPVAGLRRYCMSELSALGNVLGFCLMRLLDRRGLDEVRMGTEALLFKHAGAACRALENGKLTHCSDACLLILAAQMSYGACLLGEHGAALVSHTLRFVEAKMSSCRVRAFRRFYHECSQTMLHEYVRKNVERLLATSDGLYLYNAFRRTTSIICEEDLDGDCRQLFPE
The following text describes a protein:
Function:
Component of the A-type ATP synthase that produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVVADLKLGSVILPRSESPRAISRLTEFEWFHKIDTENDLVTPEIDDLLLEAQKTYQSIDDVVKGLGVPPTVGILEILFKGTMIKKKDYEIGEIEDLVEDLKKKTPSVIDEPAKLLEEQADTKRGIEEYRSLKETLEIAKKLNIDLSGFGLMKYFYTNLFVIDSGDYEEISRALEGITFYKYDLESKDKAAVLVICGIDDSEKALKVLRGFNANPFSIPDGMSQIPSEAYATAEAKLKELTAKQAQIAKQLAKITKNIRRDILVLHEEALVAKDVLETLRKPGGTKHFALIQGFIPSKMEEKFKNITSQWTSVTEEITDPKHQEQVPTLFDNKKFVRTFEVITESQGIPRKGEADPTPMIALMWPIFYGLMFADTGHGLLLMGMGLLFKFKGQGNLSRWGMLIAISGAASAIAGVGAGEAFGYHIYYFEPFKGLLAEGGPLYPVSFIVGILSVAELSFEQVINILKVSLFIGIIHLVWAMILRIRRLAREGHKIVMYLEAIPNITLYGGIVVIMMCAIGSQYDVMNMYSKVHTEAVPWVTIFLGDWAQVWIVTRIAVVIVIASMAMMMVGGIMHAKKHPEDGGSAANVVMEVFLGKTVESLAHTISYARLGIMLLVHAALLLTVNNAFNSLGGSESFGAWAMIIGGNLGIMMIEGLIVYIQSLRLHLYEYFTKWYDGGAQPFRQVRPELIYNQFIWKRK
The following text describes a protein:
Function:
Acyl-CoA synthetase required for both the import of long chain fatty acids (LCFAs) (C14-C18) and the activation very long chain fatty acids (VLCFAs) (C20-C26) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. The transport and fatty acyl-CoA synthetase activities are genetically separable and are thus independent activities. Esterifies VLCFAs in the peroxisome matrix. The VLCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Peroxisome membrane.
Sequence:
MSENEKRPDLEDQDQDQNQEQAGGRKMEILLELNLKQKLATRLGTILLATVIFGAFCWDNALASLTLGAVVALLLRNPTFVFALVMTASRDLKAFQRFVALNIYLLRKDRGGFTVARCFQDQARRRPKKTCFVMDDRHLSFAEALEFSQKIAGYFSDRGLERGDCVALLMETRLEYPCIWLGLSQLGVITALINSNLRGESLLHSIKVANAKALIVGSELLDVLVSLREKEQLDEVPIYQYTDDEVRGVAGHDLLPGAVDLVTALKTQKKLELPSAVCPGEARSKLLYVYTSGTTGLPKAAVITNLRFLFMSAGSYYMLKMSSDDVVYDPLPLYHTAGGIVGVGNAILNGSTVVLRKKFSARNFWLDCDRHNCTVAQYIGELCRYLLATSYSPDQQKHNLRLMYGNGLRPQIWSQFVRRFGIPHIGEIYGATEGNSNLINITNRVGAIGFVPVYGSSLYPVQVLRCDEYTGELLKDSKGHCIRCQPGQAGLLVGKVDARRAVSAFHGYADKGASEQKLLRNVFTSGDVFFNSGDMVVRDILGYFYFKDRTGDTFRWRGENVATQEVEAIITNCVGLEDCVVYGVQIPHVEGKAGMAAIVDPERKVDMDYLSVVLRGSLPPYARPLFIRLLDEIPRTATFKLKKRELAKEAYDIGQLSDPIYYLNRDGIYRPLSQEQHELLRSGKAGL
The following text describes a protein:
Function:
Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.
Sequence:
METDAPRDANASASARAEEAAQSPEQNKSKDNNANSKRKRQNDKQRKGSNGKNSDVQLSKSLSWVLRHSAPSLGLRPSPDGYFSVEDMLSLKHPRFCNKGSSHNGGRKYTVDDIRRVVESSDKQRFRLEYKDNQYLAKMMKHEKSSDRGETAATSNAKESTNAPAKLDGSSDNESNLVLCIRANQGHSFSKHIESDKLHTPLTKEELSDPNLTIVHGTTRKAWEDHIRIEGLSRMKRTHIHFATGLPTSDNKPISGMRATSQIYIYINGEKCAKDGVPFFKSDNGVILTAGVNEDGFLPVKYFRKVVMAFNDKVLLDDDDEDD
The following text describes a protein:
Function:
May be involved in neurite outgrowth.
Sequence:
MGTIPNPQRTVTVQMVSPLSVADHLGSKESYEKRDEEPNLKLNRAFSTPAEHRQGSVCLKQPDDGSTNKPLDCEKQSRVDISTPTASPNGAHKESEIIIAKELVCSGDSKNRCNSDIKEDNRGNNNNFRVLSTVHKEDISNASQTLMIISSKAGLQADNSTVKLQSPAKAFVESKAQGSSTEMTKNLHKCHDKADPTRTSMQDHCLKESLESKQVKDSNTGISTSKDKSLSEKSKELVDSDTTTSVQMHNPDTLGSKTQRSKMETSDVKKESGPGCVDKDLKTLESFESASFENVPAFLARDAAGSGGQQGGLTLAQMAGQAAHAHGALQGEETQNQQEHCKQFKEAGTMTVRAECSPVPMKKCQDVEVQAVTSVQSRSAATSPYLFPPVLPHMFCSEMKEDSENLTVVYHNTSNQCVESLSEKTTLESDLSQTVCQNKVHHSGSVLLHETGPGAKTKATGQYICSPKTDLPALQPVYQINIETPSQTNLIPTLMVQNTEHAASQSLNQQEPGNNSQAVQKCKSSLSEKPITTNHACQVAADIATVPTQPSNSKCHANRASSSCTQADPPHGEKTRRRSKSRNVQRTSQQSRKETEKNANQRKKAGGQPKASKNIRDVVWDEQGMTWEVYGASLDPESLGFAIQSHLQCKIREHEKKIMSQTKGRRSVSSETSPGKKTKRRQQNVFRSVLQNVRRPNCCIRPPPSSVLD
The following text describes a protein:
Function:
May have a role in the maintenance of the nuclear envelope structure and in minichromosome stability.
Sequence:
MQYVGRAFDSVTKTWNAINPSTLSGAIDVIVVEQEDKTLACSPFHVRFGKFSLLLPSDKKVEFSVNGQLTGFNMKLGDGGEAFFVFATENAVPRELQTSPIVSPTTSPKQTPSINVTEPQDLELDKVSQDHEKDQSNTYLMEDGYEFPLTRDLIRRSKSDADQTPPTGFKHLRHSSCLEMAGSDRTPSMPATTLADLRLLQKAKELGKRLSGKELPTRVGDNGDVMLDMTGYKSSAANINIAELARETFKDEFPMIEKLLREDEEGNLWFHASEDAKKFAEVYGHSPPASPSRTPASPKSDSALMDEDSDLSRRHSLSEQSLSPVSESYPQYAKTLRLTSDQLRSLNLKPGKNELSFGVNGGKAICTANLFFWKHNDPVVISDIDGTITKSDALGHMFTLIGKDWTHAGVAKLYTDITNNGYKIMYLTSRSVGQADSTRHYLRNIEQNGYSLPDGPVILSPDRTMAALHREVILRKPEVFKMACLRDLCNIFALPVPRTPFYAGFGNRITDAISYNHVRVPPTRIFTINSAGEVHIELLQRSGHRSSYVYMNELVDHFFPPIEVSTRDEVSSFTDVNFWRSPLLELSDEEEDDTNKSTSKSPKTPKNTKFGYQEFEGIDEEDAQDYSPSPLIKSFNELMFEGEEDEEGEEDVENAV
The following text describes a protein:
Function:
Copper amine oxidase-like protein that does not show any copper amine oxidase activity. May be the appropriate amine substrate for cao2 has not been identified yet.
Subcellular Localization:
Cytoplasm.
Sequence:
MAEESKAAEYFDPLDPLSFNELRYVVNLVRKSYPEKQISFDVVTLSEPHKEEYVHWRYSSAHEGIPDRRAYVIVLEKEVPGVFEGIVNLTTGKIEKWEHSVDTCPIITADLLAITDEIVRNDANVIEQCKICGVPESGLSNVYCDPWTIGYDERYGSGRRLQQALMYYKPGDSGHLRSIPLDFCPIIDVDQKKVIAIDIPKVRRPIPQDVNSDNNLKKLEQEMEAMKMLKPLRITQPEGVNFRIKGRYIEWQNFCFHIGFNYREGIVLSDVVFNEDGHLRPLFYRISLTEMAVPFGAKGHSHHRKHAYDLGEYGVGYRTNPLSFTCGCEGVIHYMDADFVNYRGEITTIKNAISIHEEDDGVLFKYSDLRDRNANISARSIKLVVSQVFTAANYEYLVYWIFRMDGVIECEIRLTGILNTNAINEDEDLKGHGTQVYPKISAENHEHLFCLRINPMLDGLRNSVATVDALRDKNGTLVSKYIIPETVTEAISNYDSSTGRTWDICNLNKLHPYSGKPVSYKLISRDTSPVLSQPGTTNSDCSGFAENNIYVTPYMDDQIFPTGDYAPQASDDTPKGLSKWISDDPNAQIKNTDIVVWHTFGMIHFPAPEDFPIMPAESIHLFLQPRNFFKHNPALDTSSSVNSTSEATSPNTHHENLRDTSQKRESHSTPHDYEPHVSDKNDKSVEDKLHFVQKDESRPKEPVVDAAQKHEGRSETLAQPGQQNANQSEEKQGGQNGSNGGHHHHHHHHYITGHVYGGYHKHSGSGGHLVDMMKNISDVTHDFAMGNFRYHKYD
The following text describes a protein:
Function:
Efflux pump that contributes to intrinsic antibiotic resistance. The pump uses the electrochemical gradient as a source of energy (By similarity). Confers resistance to rifampicin. Confers low-level resistance to tetracycline and to several aminoglycosides, including streptomycin, gentamicin, 2'-N-ethylnetilmicin and 6'-N-ethylnetilmicin.
Miscellaneous:
MISCELLANEOUS: Point mutations found in this efflux pump in clinical isolates can play an important role in conferring clinically relevant resistance to multiple drugs, including pyrazinamide, and could explain some previously unaccounted drug resistance in clinical strains.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MRNSNRGPAFLILFATLMAAAGDGVSIVAFPWLVLQREGSAGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSGAAVAGVPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGWSLDRINGAYEAILNLAFIVGPAIGGLMIATVGGITTMWITATAFGLSILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLRFVWNLRVLRTLGMIDLTVTALYLPMESVLFPKYFTDHQQPVQLGWALMAIAGGGLVGALGYAVLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLVYGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGPLTDAAGLHATFLALALPIVCTGLVAIRLPALRELDLAPQADIDRPVGSAQ
The following text describes a protein:
Function:
May play a role in cell differentiation in the intestinal epithelium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MADTTEDSNFIFSRKAIVLTLEIALCLIATICKAMSFGCYLWGSIVELVWAIIIFIVYAMKLDVLLRFLPWTDFFRAITGTLLLFICSLVCLKFAVTNEFSMEIAGSVFGLLAATVFGFDTLCIIKQIKELNEESNIILI
The following text describes a protein:
Function:
Together with CGR2, required for homogalacturonan pectins (HG) methylesterification in the Golgi apparatus prior to integration into cell walls, essential for general growth and development. Promotes petiole elongation. Impacts photosynthesis and respiration efficiency by influencing leaf mesophyll morphology and physiology; pectin methylesterification modulates both expansion and positioning of cells in leaves, probably by changing cell walls plasticity.
Subcellular Localization:
Golgi apparatus membrane; Single-pass membrane protein.
Sequence:
MSRRQVRRVGDSGSFPFVGALHSKSRSSPLLSVCLVLVGACLLIGYAYSGPGMFKSIREVSKITGDYSCTAEVQRAIPILKSAYGDSMRKVLHVGPETCSVVSSLLNEEETEAWGVEPYDVEDADSNCKSLLHKGLVRVADIKFPLPYRSKSFSLVIVSDALDYLSPRYLNKTVPELARVASDGVVLLAGNPGQQKAKGGELSKFGRPAKMRSSSWWIRFFSQTNLEENEAASKKFEQAASKSSYKPACQVFHLKPLH
The following text describes a protein:
Function:
Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MEDTPLASLSLTHVHYNPEDPLSLLSAWLALVPQALCVAYVTLIWASREMEVILMFSGQMGCEAFNFVLKRIIKEERPKQMLGKGYGMPSSHAQFVTYFAVYLTLFLLVRHIPTVPKPDTTSYFLMRMALAAGVCLGAGAVATSRIYLNYHTPKQVLAGCAAGVLCAVSWFVATSFLRTEGYVDWVLDLGISQFLRLRDLVVSQDLAEAGWLQW
The following text describes a protein:
Function:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQQETQAPPLLLLYARSISKTNYIFRVSAMDENYENFTDAYEEMWGFDANETNTFASSEVRVISLVVYCLTFLLGVPGNSFVIFIAGMKMKRTVNTIWFLNLATADLLCCLSVPLTVAEILLDHHWPYGYAMCKILPSVIVISMFASVFTLNIISLDRFTQVITPVWAQNHRSLLLARLSCVAVWILALLLSLPFMILRRTYEEFNMTVCTFDDDDFTTYGALSIVRFVFGFLIPLMSIVTCYGIIARKLGSRHFRSGRAFRIMLAVIVAFFLCWMPYHVLDLIRSYGGESSSMVALKVDPLAISLAYVNSCLNPVLYVFMGQDFKNKVQLSLRRVFERAFSEEGTQISRSTQSQQVHSVL
The following text describes a protein:
Function:
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MLGVLCARHKPWILNSISLLAHGSFAAHHQNRFVYSPIHVQSPERRRHHSTACRLGVGGGGLSVGGGAASIWHAILPSDGCSGCRRRRNGRRKPGEGSWNAASDERPARWLHRADSAWLLFGVCSCLAPIEYWTDSNDSNPETVTFYEEKISKIDGGGGGDDLNVKRCEIINERPFKVTGVLADGRCLFRAIAHGACLRSGEEVPDEERQRELADELRAQVVDELLKRRKETEWFIEGDFDTYVKEIQQPYVWGGEPELLMASHVLKKPIAVFMVVQSSGNLVNIANYGEEYQKDKESPINVLFHGYGHYDILETFSEQK
The following text describes a protein:
Function:
Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEKHSINDKQVVLCISVDVSQDYSQVENVIKQAQEKLGPVDMLVNCAGMSLSGKFEDLEVSTFERLMSVNYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEALQMEVKPYNVYVTVAYPPDTDTPGFAEENKTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSIGSDGYMLSSLTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQRARSEIADKTA
The following text describes a protein:
Function:
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein.
Sequence:
MEAPAPRWVPTHVQVTVLQARGLRSKAAEGQGGSDAYAVMAVGRDKFSTSVAERCQGQPLWREEATFELPPPPRPAALRLTVLHRALVGLDKFLGRADVDLAALREDGGRRHCRWYKLRSKPGKKEKERGEIEVDIQFMRSNLTASMFDLSMKDKARSPFGKLKDKLKGKRSSGLSDTASAIVPSTTHSPADSEDEASEKEKKKSKFKTLFSKPGLQKTSLSQSLSVLPTPQPVAAGVRLRPRDFQPQWDDEDLETSPTSERTFEIALDEKSSPVFKPRKAATLDSRQLNQPAAGNTKKEGLSLFSGLKSKNDPVSKSSLCINGSHVYMEENTLKDSTPASSPSPRNFRKKQGSASEENLSSRSTKGPEEMGRTSPSYALSGSASLETFKAMSLPSYKLLSGEEYVENSPPVSVEVTRETKKTDQKKSALLSLVTGKKEAVKNSDAESIPDRSQKEEENKDAEEKSEQEAKCLEPPADVSRGNPSEDTQPEVFTSKQLLNPFEEERKPEKAAAPAKTKAVKPRLGVSSEEETKATLPTLAPDSLPAYLSVHHISSDNNPFVSKMGQKVPDSEGVTSASLPSPFTEELLSGKNPFNPSWGRVSPALGSDHVVIPSSHHLAASTPKGQISRSGNNPFASEWGQGPEGSDAHASVSPLPVPSPRSGGHFNGNNPFISKTGWVADAPGLTAVTASSPVGLPGDGDNSSAGLSADLSYSAVTASGSSSSVASTHNVNAVANPPDAPSVNPGVAPKNQCDSVQVQVGPSLNRSKLVLFAENGAEQPPSSESELKEKQELWSEKRREEHSPPSEPQEAPPDTKESSPVGSVNPTLGAHTQPPRETAAGRAGREGAVTPQPAPRLSLMQKCPPVSQADELSVGPSGEGEGSACGLALQNEKAPGAHEYLPQNGSVTALVPPVKLRADSSSRCVKKEGDEDLFDSLTNLKSALSVTGDHSVRLAALPAIPEAGSDDELQGDCQENQGIAADGQNVLESVDRTPLHENQKESSLSSAAGGVTLSAGGGSAVPVLPAGGHGHGVSKQTPDSGMTSHSSEHSCCFEKQVISTGAGKRAESDFFEPSVSSSSLSCSSQPCSSSHSLSSDTPSQRAESPKKPTAEGFADKAGNSGKKKLLQAWVSPSETYPNQTQQSGETMSPKHRLHPVKPMNTTANKTQSKDLNVISAMNEKLLEMNIKKYNPSDPAYAYAQLTHDELIQLVLKQKDTITKKDLQVRELEDYIDNLLVRVMEETPNILRVSTSGNRKAGKM