lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSCCGGQNRVRPFNDGPVQVEDDFNGPLSERSCRDIPCLIIFLAFLGGMGYVTYLALRDGNPDRLIYGDDSYGNICGKKNNPIENVSLSGRDMTDKPYVFFFDDVAMSKLKPTSKRLCVSRCNNETVFTRGGLRDLAVNNITRLCTYDVDVDDYVHATQGGMGECPQTPIAARKPILFRCVRADVIGVASSLLQNDIFQSALADIEKSWREIVYLCLIAFGLSITVVIALRFLAAYIIWSMVFGFILGSMGGSGFLWYMWYIARAALRETPAELQLAQDKSNLKTTLIYASVATTVTAILLLILLVMFKRIALVVTLFKEAGKAIGAMPFLLTQPLWTSLFLLSFCAAWVYIYLYIATAGHPKATPDGLVEYVKDSFSKYMGWYYIFGLLWVTQFILACQECTIAGAIAEWFFARDKSLLSTPILKSIYRIIRYHLGSLAFGSLLIAIIMFIRIVLGYIQSKLKGAKSAPAQYCLKCMQCILWLFEKVLRYINRNAYIEIAIYGYNFCKAAQKAFSVLVSNALRVAAINSVGDFLLLLGKFAVTACVVVIGLQLLQDREDLNCYAIPIALAGVCAFFISHVFLLVYEMAIDTLFLCFCEDSERNDGVQKPYYMSKQLMTFVENAKKAQAISKDAKDVAKEARV
The following text describes a protein:
Function:
Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing.
Subcellular Localization:
Nucleus speckle. Nucleus, nucleolus.
Sequence:
MAADSDDGVPSVPTPSDGGVNRTTQSAEEFVVRVPVVDVQSDNFKEIWPSLLLALKTASFVAVDTELSGLGDRKSLLNQCIEERYKAVCHAARTRSVLSLGLACFKQQPDKGDSSYLAQVFNLTLLCMEEYVIEPKSVQFLVQHGFNFNRQYAQGIPYHKGNDKGDESQSQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPENLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAAGSPHVALEFCSYPSSMRGHIDYRCCMPMAGAL
The following text describes a protein:
Function:
Required for the synthesis of PAI consisting of 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-dodecanamide also known as N-(3-oxododecanoyl)homoserine lactone, an autoinducer molecule which binds to LasR and thus acts in elastase biosynthesis regulation.
Sequence:
MIVQIGRREEFDKKLLGEMHKLRAQVFKERKGWDVSVIDEMEIDGYDALSPYYMLIQEDTPEAQVFGCWRILDTTGPYMLKNTFPELLHGKEAPCSPHIWELSRFAINSGQKGSLGFSDCTLEAMRALARYSLQNDIQTLVTVTTVGVEKMMIRAGLDVSRFGPHLKIGIERAVALRIELNAKTQIALYGGVLVEQRLAVS
The following text describes a protein:
Function:
Putative pheromone receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
ASNIFLIKTMNILYSSDTTLGILPVFQSGIGLMGNLLLFITYMYIFLFWPHQKNPLDVILMHLTLANVITVIIRGVPYIMSSFRLRSTFVDTGCKTGLYIYKMTRGICVCTSSLLSTFQAVIISPCHSKWFIYYHAMIFQSAMFTQGFLFLFLMIWTSFYMVTIFLRHQKTVFHIHSISLSPQPFPETEASHVFFLLVSRFVFFYGTNVCLSTYISSMYENSLILENITSFVSSSYPIICTLILINYDNKVSRLTCAILNMIISPCLPHSFLLHQRNPDKNYFNHKRMCF
The following text describes a protein:
Function:
Histone methyltransferase that monomethylates 'Lys-5', 'Lys-8' and 'Lys-12' of histone H4 (H4K5me1, H4K8me1 and H4K12me1, respectively), thereby controlling gene expression and remodeling chromatin structures (By similarity). Monomethylation of 'Lys-5' of histone H4 (H4K5me1) is required for subsequent acetylation and formation of N6-acetyl-N6-methyllysine (H4K5acme).
Subcellular Localization:
Nucleus. Chromosome. Cytoplasm.
Sequence:
MNPYETEIYKVVPIPNKGMGMIAKVKIPVGTRIFAETPLIRTKSDAKEIEEALSTKTKEEQEAFHRLFNAHPDTMGPFLGPFYSNALTIDETKGGMFLLGSRMNHDCSPNVKHTWNPRLDQVTVHAVRDIEAGEEILTTYIDLHKSHTERQKILLEHFGFKCYCSVCSVEERKIRKISDLRRKQLAYYDRTMAKMCIVNPRGALRALRHRIHIAHEELLFGRLDIIALLDAFRLCVIHGDFERASIFAKKGTKAISLYEGTDSEKYLKISKYVENPRSHALAEGVPALPLFLEEDDELSDLEDNLWGCKLEEDVYSDTD
The following text describes a protein:
Function:
Component of the N-acetylglucosamine catabolic cascade that phosphorylates N-acetylglucosamine (GlcNAc), and allows the unique ability to utilise GlcNAc as carbon source. Converts GlcNAc to GlcNAc-6-P. Also able to phosphorylate glucose, glucosamine (GlcN), and mannose. Galactose, fructose, N-acetylmannosamine (ManNAc), mannosamine (ManN), galactosamine (GalN), and N-acetylgalactosamine (GalNAc) are not phosphorylated by HXK1. GlcNAc metabolism is closely associated with virulence and morphogenesis, and is involved in the cell wall synthesis. Acts both as a repressor and an activator of genes involved in maintaining cellular homeostasis. Contributes to white-opaque morphological transition and plays a role as a filamentation repressor.
Subcellular Localization:
Cytoplasm. Nucleus. Mitochondrion. Note=Localized in cytoplasm and nucleus in a filamentation-inducing medium whereas in 2% GlcNAc, where catabolism is more prominent, a major fraction is seen to be present in cytoplasm. Localizes to mitochondria in non-fermentative carbon sources like ethanol.
Sequence:
MTETSISGLRGPKSMYFMEIVDVSSQESSVLSSIVESFTSAVSASNLGVYSDEVLCDIKSSLKENSPITMLPNYNVSPTGDEHGQYLVIDLGGSTLRIAVVDISKPHPNLSRSERITIVVEKSWIIGNDFKRIDGEFFKYIGSKINEILMGQNVIDVKSVINTGITWSFPLETTDYNRGKIKHVSKGYTVGEDIYDKDLKMVLEDTLRQEYGLTLDVQSILNDSLAVYSAGCFIDSKMKLAMVLGTGINMCCSLKRSSDIHPSKMLADATLFNCELSLFGQNLCKDFATKYDIIIDKRFAGLSHHFKTFMEPDPITKTLFQPHELMTSGRYLPELTRLVVVDLIEAGEIFQNVDHQQMYQEYGGFSGELICFVHENDDYDDIHDKLCKAYGWTTVGLSDIVCLKEVVSCIIKRAAFIVANAIIAFFKLLGSDELGGDVTIGYVGSVLNYFHKYRRLIVEYVNSAEEAKGIKVDLKLIENSSIIGAAIGAAYHK
The following text describes a protein:
Function:
Chloroplast omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol.
Subcellular Localization:
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Domain:
The histidine box domains may contain the active site and/or be involved in metal ion binding.
Sequence:
MASRIADSLFAFTGPQQCLPRVPKLAASSARVSPGVYAVKPIDLLLKGRTHRSRRCVAPVKRRIGCIKAVAAPVAPPSADSAEDREQLAESYGFRQIGEDLPENVTLKDIMDTLPKEVFEIDDLKALKSVLISVTSYTLGLFMIAKSPWYLLPLAWAWTGTAITGFFVIGHDCAHKSFSKNKLVEDIVGTLAFLPLVYPYEPWRFKHDRHHAKTNMLVHDTAWQPVPPEEFESSPVMRKAIIFGYGPIRPWLSIAHWVNWHFNLKKFRASEVNRVKISLACVFAFMAVGWPLIVYKVGILGWVKFWLMPWLGYHFWMSTFTMVHHTAPHIPFKPADEWNAAQAQLNGTVHCDYPSWIEILCHDINVHIPHHISPRIPSYNLRAAHESIQENWGKYTNLATWNWRLMKTIMTVCHVYDKEENYIPFDRLAPEESQPITFLKKAMPNYTA
The following text describes a protein:
Function:
Involved in the lipid remodeling steps of GPI-anchor maturation.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MPWASCCRPHGVRVFGAILAVVLFLEPGLASSGDRSWVFQSCLAHCSSSGCTRLPHVPVSEQQALGIYSCPAACASALQAGHKQPGMPGASPVPLPLRLFRWSCEDDCKYHCMEAVEAWKARAGGQQEHGGSPQLQRLPVEKYHGKWPFRRVAGMQELLSVLASLANLAAHAVCLARLRARAGRGVSRVPSLPPSAGMAATRSPGGVGTGGLDGALCRLPYPFLGLWTAYSALHLNAWLWSALFHCRDTRTTERLDYCSAVAVVAAGLAAAMARPLWGRTRRRRVAAVTAVAGVVAGLIAHLRYMLTVKFDYGWNMQVCVAASVATALIWLVWVWAVRHPARSRMTAFLLLAHAAMLLEVLDFPPPTASGRLLDAHAAWHWATVPLTALFYSWLQADADWCQAGLAQGGQGGADGGEAGARGGDAGAVGRMLEAAKHKAV
The following text describes a protein:
Function:
May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MEFALSTMVCLFLHLFPLYSYCYCCCTYPFSDGLFTYNLSFVVVLLFSLLLFFLFLSFFFIVIVMMVSLVGLAAMMLSNAQESFGSAFSSAGNFFGGVKRQAFGMFSDEPPAEVEVLDIPEDTGLIGDVREMMDLSYSQRLWAFFMVLGMGIVFIVIAALFAPTVALFPKKFAFFLTVGNMFCFGSTMFLVGIKQQLHSLFSAKRLEAGIAFIVSLLLTLFFTLYWKSSFLAVFFAVVQVLSMMWYALSFVPFLRTAVATVSSYMCRATGSIIGFFRG
The following text describes a protein:
Function:
Transcriptional activator that binds specific DNA sequence.
Subcellular Localization:
Nucleus.
Sequence:
MAAAEARGGEFPVGMKVLVVDDDPTCLVVLKRMLLECRYDVTTCPQATRALTMLRENRRGFDVIISDVHMPDMDGFRLLELVGLEMDLPVIMMSADSRTDIVMNGVKHGACDYLIKPVRMEELKNIWQHVIRKKFNENKDHEHSGSLDDTDRNRPTNNDNEYASSANDGGDGSWKSQRKKREKEDDETDLENGDPSSTSKKPRVVWSVELHQQFVNAVNHLGIDKAVPKKILELMNVPGLTRENVASHLQKFRLYLKRIAQHHAGIPHPFVAPVSSANVAPLGGLEFQALAASGQIPPQALAALQDELLGRPTSSLALPGRDQSSLRVAATKGNKHHEEREIAFGQPIYKCQNNAYGAFPQSSPAVGGLQPFAAWPNNKVGMPDSTSTLGNVGNSQNSNMLLHELQQQPDTLLLGTLHNIDAKPSGVVMSSQSLNTFPASEGISPNQNPLIIPSQPPSFVSSIPPSMKHESLLGLPSTSTSLLGGLDMVNQASTSQALISSHGTNLPGLMNRSSNAIPSPGISNFQSGNIHYVVNQNAMGVSSRPPGVLKTESTDSLSCSYGYIGGSTSVDSGLFSSQSKNPQYGLLQNQNDVNGSWSPSQDFDSFGNSLGQGHPGTTSSNFQSSALGKLPDQGRGRNHGFVGKGTCIPSRFAVDEVESPTNNLSHSIGNSGDIVNPDIFGFSGHM
The following text describes a protein:
Function:
Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Secreted, extracellular exosome.
Sequence:
MRAAAAAAAALVWVLWLVAVCARPCSAQIAATSLPPEDLDGSGDDDDNFSGSGNGPMPGVSVIDLSLPTRTNTLLTSVSAASTTYPPIHREESNTEATLTSPSTEKDNEKLLVLSDHMHESSYPNEGATTGPVKGTTGQPTTRRPSTIKVTTVRLTSTVHNADLPNSRRQNASRIFPGVFDSTLERGSEGAVTASVSPEKASEMLTPFAETEGSGDISDFHFVGPSEPPDIEVKHDPGKETPVDKGATGAAQGILDRKEVLGGVIAGGLVGLLFAMFLVGFMLYRMKKKDEGSYSLDEPKQANGGYQKPQKQEEFYA
The following text describes a protein:
Function:
RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
Sequence:
MSPNTSPNMGRGRAPRGFPPYRPENNLHNQPHRHSFDVDFKIWSMPNASAEVGDRPPSTSSGSNDWSYSYSNQTAHTRNGTNGSSPRTSVPPGLAYRLDGISSSMRRPSHDNGFGAMEHASERLSVGGFNVASSGPSEPAERQGLGLTPYAAQHSHRSSVVADSSTLSVNWQNNRASVGDLDAAQTNVPWLARKPAEVTDTDRPMFSSNLWSNSSHTVAASARPFTPASPTAWENGSGNGLQTSNGVQTGNGFQSGNGFQAGNGFQTSNGFQTGYNANGFGNYTGAQQSRSNFSQAPSRREFSSPTNIDRRASTQSFIQQPQPTTNLPFDTVTLQQQLQMYNMAHNLGMAGAYSNPSLPTTGLAMGAMSSGSMQSGKLREYLNTRNAPQKWDLKQIYGSIADFAADRAGSRFIQDKLQSASSEEKAEVWRELMEELMPLMTDVYGNYVVQKFFEHGTQEQKTSMAGIIKKNMLRLSENKYGCRVVQKALDNIFRRYQVELVNELKDHVDKLNKSQEGNHVIQMIIKLLPRDEIGFIYDSFRGPGKVMELALNQYACRVIQRALEHGNEEDRLYLVSELHKGAHTLITDAYGNYVAQHIIEAGKPEDRARMIAAVMSQTITLSTHKHASNVVEKCINYGTPEDVRRIRDMFFSPQDGMGGYSSDHQSPDSFLRFLMLDHFANYVIQKLVKHSTFSNEEQQFFIDTLEPKINELLKNHKGLDERQRNALKRFQGIINELRKDIDKKEELAKNGSSAPPSLDPASPSLHISSALPTPDGGSEPNSPLDLGMTSSANTTSPIGSADGNGSNGKQSLLVVNINGGLDATDAFAQLHIH
The following text describes a protein:
Function:
Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MDDQFDEFGNYIGNDQVIEEQPHEDDMDNNNEDELNRNEDRKNQIVLHEDKQYYQTAEEIYGSDVEVLYRNEDEQSITEGIIPVEKNKKIQREYKTNLTSKYDFEYISEQMNNIDKIRNIAVIGSLHHGKTQLIDLLFRYSHDKSIDVDKITTNYMDIRNDEQELKISIKSSQISLCIPSKKNGYYLCNIIDTPGHSDFIDEVIVGLSLADNVIITIDCAEGVLLTTKHLIEIVAQQHLPLIVVITKIDRLIIDLKLPPEDSYCKIRNIICEVNEILHKYQMKLISPENNTVLFESSIFGCLFSLNSFSEKYIPKTTKGTLEQRIRGAIGFDSQIFGQNMWGDKWFDHQTHTFKRIKGNEKRTFVEFILEPIYKIVGMCVSKEGKELKQGLKNFNIRLEGNESELNFIPLLRTVFYKFFGERNLTGFGDTLQELMTPKEAAQKVITKLSNDKIEMKDIIKKCDRNGPLVMSIIRLLPNTRSSEMIGVCKVYSGTIHEGDSVRVLGNNYSETNTEDMRIEEVLSVQLDMAQYKVPMRQGIPAGNICIVTGINQIISKNGTVVDKSLTEIQHIRNIEIPTPYIKVAIEPLKPSEKEIMIESLSKVTQSYPGSMVKCEDSGEYIITGYGEMYLDCILRDVRNMFTPIEIKVSDPCVIFNETVSCLSQMKSVALSTNHRNRIAVIIDPLDENTIKGIEKGELKEEKGRDEILYKKYQWDILASKSLLCIGPEEKIPNVLLNDILEEEKREKINEMKEACCIGFKWAMSSGPLCEEEMRNCRVRIIDAEFERNVDEQQVIQALRRSIYAGIILSSPQLLEPIYVVEIITPENAIKGITKSISDRRGFIIQQQPLEGTPFQQIHGNIPLIEIFGFETDIRTFSRGQAFVQSWFSHWGNVPGDPLDKEIKPLNLQPNPQPYLSREFMMKTRRRKGLVDDVDTSKYFDEEMLSTMSQNNFIF
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MKQAIQRFLLISKFVFRMIPNLRIVECNIILQNFASLYFTIQEGYYGLLDIPLVSVAHNSYLPNESTHQFTLILDMDETLIHFVNQTKSMRLEYLLLDQEIMQIGFLTKSLLINKSNLDYIDNMPYLSRLGRSIAKCIIIDKIAANYQHQEENEIQIKIWCNDPEDKELVKVGAILRQLAKGNCEDVRDALQMYNKAYVQ
The following text describes a protein:
Function:
Probable transcription factor which binds the E box motif 5'-CA[TC][AG]TG-3'. Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs. Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis. Required for specification of cell fate, acting in concert with lin-32, in the development of the male-specific genital sensilla (simple sense organs) known as rays. Involved in regulating glial specification, perhaps by suppressing a glial fate in different lineages during early embryogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MSWEQYQMYVPQCHPSFMYQGSIQSTMTTPLQSPNFSLDSPNYPDSLSNGGGKDDKKKCRRYKTPSPQLLRMRRSAANERERRRMNTLNVAYDELREVLPEIDSGKKLSKFETLQMAQKYIECLSQILKQDSKNENLKSKSG
The following text describes a protein:
Function:
Enhances the transfer of lipids between membranes in vitro. Active on phosphatidylcholine (PC), 1-palmitoyl 2-oleoyl phosphatidylcholine (POPC) and ergosterol, and, to a lower extent, dimyristoyl phosphatidic acid, stigmasterol, desmosterol, beta-sitosterol and steryl glucoside. Inactive or poorly active on palmitic acid, stearoyl-coenzyme A, cholesterol, glucosylceramide and ceramide. Required during seeds and seedlings development.
Subcellular Localization:
Peroxisome.
Sequence:
MANTQLKSDAIMDMMKEHLSTDAGKEVTEKIGLVYQINIAPKKLGFEEVTYIVDLKKGEVTKGKYEGGKVDATFSFKDDDFVKVATGKMNPQMAFIRGAMKIKGSLSAAQKFTPDIFPKPSKL
The following text describes a protein:
Function:
Glutathione (GSH) transferase homolog, that might be involved in selenium metabolism.
Sequence:
MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIACAVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLARYEIRNEYGLADPELYKAADKDDPEALLEGVAMAGLVGVLRQLGDLAQFAAEVFHDLHEEVMATAARGHGLIARVQQLEAEVPSIEKAFLSQTDQSPFFTNAGVDWHPNLRMEENLITRGDLPRFVMDSYEECRGPPRLFLLDKFDVAGAGACLKRYTDPSLFKVEAASSGIEVQREKKTRKVKKKGSRWRMGDTPEVVPTSHAKLHQLFLEERVENGHSDPARIVKLKRRQLNGSPFDLKPGKSYMEKFLGTPSPEHKVVCEVSVNQSPLRLTLDNSSESGLEILEIGTVSPPRNSSQGRQSTGSSPIAQDVVLKSYTLELDEEAITRETMKVPDPISGGEDDASPYIIHKVAIEDELAIDGDRKSEESLDGDHSDELMSEVDNYMDALTTVESEMETDNEYKSKDYQGLLKVGKHGTDSDANEEHLDIRANFSDSQSFGNSSTSDDGKGSFKKGRPSFSYSDSHSNVAENIQSDIEGAVEVFPSSENYAAEIADSPLDQPSLCAENIGIQSSELIVYNNNTYNEEETIPNTGEASCNSCLSDSNSLPPPSAPVANSIVVSSAKTVLDEPDYECVKLGLESLNTNQKATYLSDSSIILSDPSQEIRNRSPADSSEGCPMEGMDHEDSNVFLCASNISDLEKEGHDGCANDVLQTDYPDGSYNKILVEEKIDSPHSVISPSNQQFPSSVFPEVDVDTGVTELSESLDVIKPVEMNSEIDDVTAATGGNSEIVTGVVEPPEVDSIKEQKCSDIAVDGSEGENDLTDIDSKVDVVGGDSVPLEDQNNYSDKLGSDDFVNLDKDVVVSPVAVATAAKDDISDDNCLAPDLICSSSSNLVDIDESLSGNQDPHLKVLDFNEVVLRECCTESEKQKEVKKLDVASTDVNSSPYNSVSDCQSNLDELENVHASVFSDHFHNRNSSYIADVTTIPSSELNNQELKSKDAHLRHSTDSSENAVSLPTCYLPEAGTVSAQHLVALQADQIPALSASKVMDEANSEPFVLQHSTPSHLEETGIPSEQSLDVQSDQPDAGCLQVHKASPKSSIMLSEQIETVSDMDQERYFGASSDQEALPSQGLLMQSAGQEDNGTVLSKNPFESAFPSFGPLPVNLEQLPPLPPLPPMQWRLGKFQPAPLVSQGEWTDHYPDTLLPTRPFTADENSKADSVLLGREGMQSSNPFFSFTSADIQKLEHSPTNSVESSVQPTSFSLDMPTVATDANSQQGNLQLEGTRSLNSYLGLPEISGKVPDDGFLASRRNPVEPSPDPLSSAVTVEHAQTENDPEPSHGLQIRYSNQVTPESVSELKVPVNNLQSSEGEERKFSDKSASPQTVLEDQYQQDLLSLHVETTWSASSLALPPTYEVGKPNGSKLPRPRNPLIDAVAAHDKSKLRKVTERVHPQVGPKIDERDSLLEQIRTKSFNLKPTAVTRHSIQGIQGPKTNLKVAAILEKANAIRQALTGSDEDDDSDSWSDS
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MAPTTPRVSFNLRVGDGKRCHIRVDEEEIHQIKSLSDKESTAAVLRNLFDLSVNSGSHISIEVADKEIHPTKQKKQDQNQEAKPEHATGNKAVVPFGSRGPRGFFDITIGDIKAGRIIMELYTDVVPRTAESFRALCTGEKSKAPNGKPLHYKRSSFFSVVPGVFCGGGDCTGVGGMFKDENFKEKHKDFGVLFMANEGKRDNNGSRFAIDLNKNTRYDGHYVVFGGVVEGLHVVRAIENVSSPSSVIIKPVLIADCGEV
The following text describes a protein:
Function:
Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility.
Subcellular Localization:
Cytoplasm.
Sequence:
MAALVAAEAAAPPGPAEAAEAAELSRALSRLLPGLEADSKLGRRRALEALQHLLEARPEAPAADPAAAAAAFQGPWARLLLPRLLRCLADPAEGCRALAAHLLGLGLRRAARPRDALPRLLPALAARLAGPEPARRPPEACEELRLALVQLLGLAVSLGGAALAPYLDDAVRVLRCTLLDPFAAVRRESCECAARLARATPDHFHMQSESLISPLMQTISHQHWKVRVAVIEATGTVIQFGSGKSVDDVLPHFAQRLFDDVPQVRQAVTCVVGGWLLSLRDRYSFFHKLIPLLLSSFDDDVPEVARVAANLWEQVGLQWQKENEEDLKDKLDFASPAPAHHPSPENRPALGCRELVFRSLSKILPAVCHDITDWVAGTRVKAAQLLAVLLLHAEDHVTQHLELLLRTLLRACADEERAVVSSAARSAELIGAFVSPDVFLKLLLSVLRKSPSPSGLLVLASVLRGCPREALQPHVKGIATALAQPHISQGAENHLYGEHLLLCVQALIAVCREDCRGSSLQLMEVLVTVMASSGATGLGDKVQETMDALATVESVDSSQDLYREHAGPLLEWLAASHHDWTVHSAELLQLDVVVTHAGPALGELLPQLIPVLRSCLQPARDPAMRLQLFSILSRVLLRAKETVDSQGQLHSYLDTLVKDILVPNLQWHAGRTAAAIRTAAVSCLWALISSESLSAEQLREVQEALTPQILTTLEEDAQVTRLVSCRIIDAFMKASGAVVGPDELVKVYPELLKRLDDVSNDVRLAAASTLATWLRRVESDGSKSCCQSDIQHLYKELLVHLDDPEGAVQDAVLEVLKAGSVLFPDLLVRETEAVIHKHRSPAHCEQLLQHVQALPPAP
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in a subset of tRNA. Selectively mediates Gm18 methylation of tRNAGln-TTG/CTG and tRNASer-TGA/GCT. Gm18 modification can enhance the stability of modified tRNAs.
Sequence:
MDSILLKLLQRESAVSPVQLIQNLLRDPSCALDDRIEALNSLCSVLESDAKGCQQHDQILPVCEEVINTICIPSLKAVNTSRVGKTKDSSQPQRLHAACELLIRCLGLSGSQSADLIESVALLIDASLRTYCEEQRLGYDSEHKDVLDVKTAVEVMNYLLKHASTLSTHHEFETQLFPRVLDTLEHSRFYTEGTASRVVGILLPKFLSNADRYQERISAIWELLLRLKTGGHDAVEKAFLLLCGLADHFFGGACSFDVTSQGEFWALLQVGLLTGTNAVTRKRAMYLLKRAIDTISRCDRTITCTDAATGLLFWWSPAHAAQLMPVWQDYILIIETLEENQVHVVKPVLPRMKTLITAMATVLPDPGCLLLHPSWLYTVYRKAFTHDNKNIHRWALLDILQLDLAASPHIITMGFTQFILGPVMSKLLQDTSLYNRLEGEKLGSCPVIGQAILPFLTKCLDMLGSAEKVQFMQDMITALSREPCGAVPLLYVTQALASVPPVPTWGDATLAHIRQVVMTHVMTNNITLRGAIQCHFAQAICNMADVEKVSLQQLASTLACLEREDGCMVRGTGLWEQVSSWLTEHGDHLLDLSSSQTGDPAPGTHLSRFLQAGVQAAIQVSPEEASGSDLPGRSEAHSIAMLLLLAVDGQMKGSQENQETALHSDSPAGVLSLESLLSPVVQVLNSARTHPYLPPAKADRCLHILSCLMQEHGTSEMARGCCASTTQQLSQVLQSCLEETLAFLVQKLTAEITKMADIGRVNMYTQLLKQFSTFYPGGNHATNLVLGSLQTLVERSISTLESQDSQQVSVVQSQLCCLAAMRSLSCVCEIVQTGPAAYRRLGEALTGAGRVLRLQDGFGKPADADSEHVSREDWGRAVCLYVESQWTVVDFLLWLPGNRACHALGSPAELLTRAMDNTEVATGMAAIQLMRTMERLIPLVHESGESLCVAAMDCAWKLVQDFYRDTDHFWPVMYSFVGITFHPALMAAPAMSAVFLRQQQYAGELFAMGERIRGVTNILLRHCCGYWAGGCSADVQTAEPSSTLAVQMSSATAHMDMILEAATFGPHFKRNLRTELDTIAYVKQLGNKCSVNEAYKGDERDDKQVRACIVNFLVSISRHQEQWTPFIELLFTRLVEKDQEMTKKVHRYHLNAYPHRYKNRVWQVVLVILPYISETLAAQYVDHLFNTLAAENQISVRYMVEWCLLLLLHRYPSLQSHLWDGLRHDSDKRIGIMASQMEITAHLGLLLEDKQEQEAFFDKAFPAVMPWALVPHFAVRVFALSALQWMWRYCQEQGFTSLMERHSLLRPCLDAKENITASKVWKKLTENWYIYNFRPRQDYSVETIFHSLPYLSGITDAEWISPNLFLQSPPAIWEDEESKPLPLWNAREDLRKCLYSLWKIKGPGIWNSQDDSKQEESQSEPPAEGNVQKKIITWRHTLEEPHLNMADMHIKVVRKGHLVVVASLIDKPTNLGGLCRTCEIFGVSTLVLGSMKYVEDKTFQQLSVSSQGWVNIQEVRPGELPEYVEEMRRQGYFLIGVEQTADSRNLTEFTFPDKSLLLLGNEKEGIPVELIHQLDVCVEIPQQGICRSLNVHVSGALLIWEYTRQQVIKD
The following text describes a protein:
Function:
Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response. Involved in JNK signaling pathway (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Not detected in the cilium. Localized around the poles of the mitotic spindle from prophase to anaphase in mitotic cells.
Domain:
The N-terminal WD40 domain is necessary for the interaction with NOD2 and down-regulation of NOD2 function.
Sequence:
MAVEGSTITSRIKNLLRSPSIKLRRSKAGNRREDLSSKVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCITSSGLLCEFSDRRLLDKWVELRNIDSFTTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASVTEASRLFSGVANARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLIKIIYVDGNTQALLDTELPGGDKADASLLDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTEEELPALPVLAKSTKKALASVPSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRFLLQVQTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGANPPGAPPEVEPSSGNPSPQQAASVLLPRCRLNPDSSWAPKRVATASPFSGLQKAQSVHSLVPQERHEASLQAPSPGALLSREIEAQDGLGSLPPADGRPSRPHSYQNPTTSSMAKISRSISVGENLGLVAEPQAHAPIRVSPLSKLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRAPGEAEKPGFPVGLGKAHSTTERWACLGEGTTPKPRTECQAHPGPSSPCAQQLPVSSLFQGPENLQPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEQSRIAQLLRDTFSSVRQELEAVAGAVLSSPGSSPGAVGAEQTQALLEQYSELLLRAVERRMERKL
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSPAPADAAADDAANYDLTSLISPYLDLHMMFPLLEYIDSLISTGSVSYSSSDVAQARLKLLKPTHMVDYAMDIYREVHGENAEIPKDMEDQKVEVFRELEELREGQMKLDELFRNEEVRANLVQNNQWNVKSLIAATSYGITSDTIAAYYKFAKFNFDCGDYQQGPAAKSSPAEDEKTGNPNMYYLTSIDTTLLQVLWGKLSCEILVEDWEEASVALVAVKTAIDLFVFWNDASGKGLESMVELFTSEKYLQAVTTHAPHLLRYLTAAVLLCKRRAAKKAGSNSNAEGRRLLRDLVKVMQQCEYSDPIVEFVDKLSVKFDFEAAQSQLARCETVLSSDFFLCKQTELFMEEARVFVFENYCRIHHKIDLTTLGEKLAMDRDRAERWIVDLIRNALLDAKIDSEEGCVVMGTGSTSVYEQVMDKTRDLTARSGGLVVNLRGYVNDARREKIRKERKATEEAEAY
The following text describes a protein:
Function:
May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
Sequence:
MERLRKGSLHTTRLLLHGRKLSTSVNISSRRVVVTGLGLVTPLGVGTEIAWKRLVDGACGITSIDSSLVRVIHKMVGRVPRGEDSYQFKADDWIGRGDKLTMTEGMIFAIAAAQQALKDADWMPENEEDRERTGVCIGTGMAGLDDISNTSSLLNTQGYRKVSPYFVPRILINMAAGHVSMKFGFQGPNHAVSTACTTGAHAIGDGFRFIKYGDADVIVAGGSEASISPLSIAGFCRARALSTKYNNCPSAASRPFDRDRDGFVMGEGAGILVLEEYSHAKKRNANIYAEILGYGLSGDAFHITSGRPDGKGALLCMERALREASININKVKYINAHATSTPVGDAIENKAIKSLFGSNSKALKVSSNKGSIGHLLGAAGAVEAIFTILAIKHSIAPPTLNLHNLHPEKDFDLNYVPLQAQELTANNESLVALTNSFGFGGTNASLCFSSI
The following text describes a protein:
Function:
Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL.
Sequence:
MTVKKLYFIPAGRCMLDHSSVNSALTPGKLLNLPVWCYLLETEEGPILVDTGMPESAVNNEGLFNGTFVEGQILPKMTEEDRIVNILKRVGYEPDDLLYIISSHLHFDHAGGNGAFTNTPIIVQRTEYEAALHREEYMKECILPHLNYKIIEGDYEVVPGVQLLYTPGHSPGHQSLFIETEQSGSVLLTIDASYTKENFEDEVPFAGFDPELALSSIKRLKEVVKKEKPIIFFGHDIEQEKSCRVFPEYI
The following text describes a protein:
Function:
Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes.
Subcellular Localization:
Lysosome membrane; Multi-pass membrane protein.
Domain:
The di-leucine motif mediates lysosomal localization.
Sequence:
MAEGLRAPPPPGNGSECPDGARWVLRLLGECARDGRDVGSALLGLLSIGCFAAAALPQFYQACKTGIMDRALSIYFLLGWLGGDLLNLIGSFLANQLPLQVYTAVYYVLADLVMLSLYGYYKAKNWGTGATASINAACLFCLLGTATTLTVLSHDTGPAPNPAAFGGRSLLSLGLEGPGPEPISKTEIIGFAIGSISSVLYLCSRLPQIYTNYRRKSTAGVSFLLFALVMLGNLLYGTSVLLKNPEPGQSEGDYILHHLPWLIGSLGVLSLDVIISFQFLAYRTGQPSAGEEREALLAEHGDS