lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Acylalkylpyrone synthase that catalyzes not only the polyketide chain elongation but also the one-pot condensation of two beta-ketoacyl units to produce the 3-acyl-4-hydroxy-6-alkyl-alpha-pyrone (AcAP) scaffold, a precursor of csypyrone B (Probable). The enzyme reaction is initiated by the loading of acetoacetyl-CoA onto Cys-155, and subsequent thioester bond cleavage by the nucleophilic water generates the beta-keto acid intermediate, which is placed within a pocket. The second beta-ketoacyl unit is then produced by polyketide chain elongation of fatty acyl-CoA with one molecule of malonyl-CoA, and the condensation with the beta-ketoacid generates the final products. Csypyrone B1 is the major product and contains a propanoic acid side-chain, whereas csypyrones B2 and B3 are minor compounds that contain butyric or pentanoic acid side-chains, respectively.
Sequence:
MIEPLPTEDIPKQSVSIVGIASRCAPHKLGADELEAIARRHYSSTPSLEKMLEINRKTRIDHRYSVFSSDHEHWHRPTIPSFSECDSLFKEYGIPLASAASARAIQDWGGVPDEITHLVAVTCTNTAHPGFDSVLCRKLGLKCNVRRVLLHGIGCGGGISAMRVAHELLLGSTQQGVPARALIVACEVPTVFARSELDIMDKTQDVNVAMCLFGDCAAALVLSNGIGHKASEQRPIWNILNCEPTQFDGTEDIAHFNVHDKGYHAIIDKRIPQLTGKCVPAGFQSLISSTPSLALEEKNYVPSNYGWAVHPGGYAVLVAAQDALGLTADDLRASYDAYRDGGNTISTTIIRILEKLRDEHKHGSNQKDKLVLAAIGHGITLETAILTRPGSSSYLHA
The following text describes a protein:
Function:
Binds L-arginine with high affinity. Shows no measurable affinity for L-ornithine.
Subcellular Localization:
Periplasm.
Sequence:
MKKLALLGALALSVLSLPTFAADKPVRIGIEAAYPPFSLKTPDGQLAGFDVDIGNALCEEMKVQCKWVEQEFDGLIPALKVRKIDAILSSMTITDERKRSVDFTNKYYNTPARFVMKEGASLNDPKADLKGKKAGVLRGSTADRYASAELTPAGVEVVRYNSQQEANMDLVAGRLDAVVADSVNLEDGFLKTDAGKGYAFVGPQLTDAKYFGEGVGIAVRKGDSELAGKFNAAIDALRANGKYKQIQDKYFSFDVYGSN
The following text describes a protein:
Function:
Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSIPAAQTEHSLGIAKELAEKFLPLMNTDKEAMTNYFGENATLVFQGRKIEGVQEIHDFLADLGEIQLSVSSYDVQTIQSARSWTMVVITGIVLLGGSVANDFHCSLYVEANESNQVAFIRFMTFNYF
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. mS41 is involved in telomere length regulation.
Subcellular Localization:
Mitochondrion.
Sequence:
MFRTLLSSTVRSIQLKPVTSTLSTTIPSITSIPTVSYFSTSPINYKTNTSTRTKENVHDLTTFLTLIGRNSIEYKDLFEDDLNKFLSTTSAQMKNMGIDTRARRYLLRWRHKFLNDLEPLREHKLGKKRNGGERKAKTVIAKRQALERLEEKEKWAQEELEAEKRGERLF
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
QLLDYHVKAFAKSVSVIVALRPEVRSVYTLKIVFVFGFLFLLSCWFRQTKIHNIGATLVGVDKIGNKYYERLGDEQYGRHRWVEYAQKDRYNASQVPAEWHGWLHYITDHTGDELLLLKPKRYGLEHKENFSGEGDAYIYHSKGHALNPGQRDWTRYQTWQPAKKE
The following text describes a protein:
Function:
Secreted protein that acts as a virulence factor during infections.
Subcellular Localization:
Secreted.
Sequence:
MKTLLFIYLQLLLLLSIIIGRVVKVEYLHLVVEVEPSTITESCLSDGIDGYSGSFYLNTTFAELMLKEHNNKRKLHQSCPLKWSSELFNYASQFAAEYSCSGILQHSGGKYGENLAFGYSPIGAIEAWYDEGEMYVYGSENVYNHFTAIVWNNTNSLGCAYKSCDTTTNLNALYIVCSYYPPGNVIGYSSQNVFPLNSKMVN
The following text describes a protein:
Function:
Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
Subcellular Localization:
Endoplasmic reticulum. Golgi apparatus, cis-Golgi network.
Sequence:
MSNDDIILPSVSSLSKLTINDVSKSGFGYNPSIGPISNTITLESSSVLLNKRTISLTPTSSDSIYDRNIITKKPHEINLSSLSFLFCEIISWAHSNSKGIQDLENRLNGLGYQIGQRYLELCKIREGFKNSKREIRLLEMLQFIHGPFWKLIFGKTANELEKSQDLPNEYMIVENVPLLNRFISIPKEYGDLNCSAFVAGIIEGALDNSGFNADVTAHTVATDANPLRTVFLIKFDDSVLIRESLRFG
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MEDWEDDIPPLVSKEQPKSKWDDEDVDDADIKESWEDEDEERLLQPVAKATEEKAPKKPLSKATEKKGKTIEIAKEEPLDPIAEKLRQQRLVEEADFRSTTELFAKKGDIKTVDNFIPKSESDFEEYAELISHKLRPYDKSYHYIALLKAVMRLSTTSLKAADAKDIASSITAITNEKLKAEKEATSKKKTGGKKKQLHVDKLDDNLVVNAYVDVDDYDFM
The following text describes a protein:
Function:
Catalytic subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MRYHGICWFIFQAAIIFAIFGSCQGAFRHQFKTAEQDGFARRNRDLAKFQKENLNWNGLFQLNSISYNSGVVSGVFEQQSENGENQHLFPFSISFLKNDVVRFQMDEKSRLEGTVEYEKNILTKRRFDASTELGFNERAEVYGKDAHLLEQTSTSLTIRYGSHGRFTVIVTFSPFKVEFQRDGEPQVVLNERHLLNMEYYRPKSSRTPEQEANGMWDETFDNFHDSKPKGPESVGLDIKFVDYGNVYGVPEHTSSLSLKETNNSDAGYTEPYRLYNVDLFEYEVDSPMSQYGAIPFMQAHKPNSDVAVFWSNAAATWIDVEKESGPSPHSQSTSTHWYSESGTLDLFIFLGPKASDVYESYSALVGRPLLPPLFSIGYHQCRWNYVSEEDVLNVDAKFDEVDMPYDTIWLDIEYASKRRYFTWDKATFPNPKAMLEKLDSKSRKLIVILDPHIKNDPNYFVSKELIDYNYAVKDKSGVDNYNADCWPGNSVWVDFFNPEAQAWWGSLYEFDRFESDKNLWIWNDMNEPSVFRGPETSMHRDAIHYGGWEHRDIHNIYGHKCINGTYNGLIKRGEGAVRPFILTRSFFAGTSALAANWIGDTMTTWEHLRGSIPTVLTNGISGMAFSGADVAGFFGNPDAELFVRWYETAIFYPFFRAHAHIDTKRREPWLYGEPYTSLVRELLRIRYRLLPTWYTAFYNSHTHGFPILYPQFLMHPEDEEGFAIDDQFYVGDSGLLVKPVTHPSIDKITIYLADDEVYFDLHDHTEYAGKGHQVVPAPLGRVPVLLRGGNILITRERIRRAAELTRNDPFTLTIAVSKIGKNASGFLYLDDGVTFNYKKGEYLIRHFSYENGILTMKDSHSNPPVSPKYSSSQKHLKVERINIYGEQTRKSIKIRKIIDSEVTEWDVSVDDSGCIRNPQLFLV
The following text describes a protein:
Function:
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment'. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity.
Subcellular Localization:
Chromosome, telomere. Nucleus inner membrane. Note=Localizes to telomeres during meiotic prophase. In leptotene spermatocytes, localizes to telomeres that localize to the nucleus inner membrane.
Sequence:
MESEKPKKTQEMKTDLKLLLECLKYHMGNPLSQKEVLITIHSVCKQNSDAGIYFREIGGLMFIINLAKSSEQSLVKEAALYTLGSIAEENVYCQQSLCTSELFQDLTGLLTNDDSNTNLKRMSVYVLLVLVSNNRNGQTLVREVGCIEVLSQMFRTVLSNYELNLSDNSVFQSYLLWSSVCSTLCVCVNNPQNDENQMLCCSLFPCVNEWLMNCMRPEVIRPICSFIGLTLANNTHAQNCFVSSGGLDVLCQVLVQLESDSHNTLSSAKLAVIVTKTMDACITDNSAAFTVVLSKYHIVSTLLALLLHESLDSREKFSIILAIGHCTEDCEKNQYELLKNNGLPLMIQALTEFKNEDLSKAATYVLHNCKKITGKLSLSLGQNSFGENEIELKDISEKETLREHWKAAKEILCRIKQFEKGGKEEKQQNRSGHYKDNTPSMKVNIQTNLKRLCADSTGGTRAEDKDINQSRELRSYKPSEIMSKACANENQLTTRKKNTNPVHPFCKEKGQSKIVHETTPSCAQNLDKEKTFDQKDSVSQSSDQVLKHLPHTVKNRKQVPETDPFTLCLDIIDREVGIQATDSCSRMLKYTCSGCIVARKLLNSRNFSKFLHSCAYQCVHHKVIMEAEDKYKNELRKTFICAKKILLTPCRRRQLCKESTASEELKIVHQKPDSKKLPGLEAQALNTSIPEAMERRSPVPGQSGLHKKRRIRKDFTKEEVNYLFHGVKTMGNHWNSILWSFPFQKGRRAVDLAHKYHRLIKGPSCAAL
The following text describes a protein:
Function:
Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.
Sequence:
MVPHPMASGTDKTQSAASSASRDPNQAHQKPYFLSLDLSTEKMGLIVVDESLDVIFGECVKFDTDLPEYGTQNGCHTDGEVSTSPTHLHVKALDILLQKVSSQVELKRVKCIGGSAQQHSSVWWSKAASTLLSRLAPNKPLHEQLSPEQTWTLPEPPNFYDMSTDAQAQSLEWLVGGSEETARRSGVRAFCRFTGIQIMKVQQTRPNILEATDRISSASSFLTSLLLGSIAPLSESDAASMSLWNMTEHRWDPLVLNCVMGKDSSLSGMSNEAKKLVQKLGEPYFDNSVALGSIASYFVRRYGFSADCQIVGFLGHHQATFLSQPLKPRDVMICLGDCDSDSVLLPLSHYLPDSTRQILPSPVKSPSNPSSNMPFMALLEYKDADLARHFLRDSYCNGSWHTFDTLVTLISEGGTIGLDDKLYTFFWPHGELGSWQGISRFEAGQRIKEFKDQRVNPRSLLESQFLTMRLQLSRISQGLRHLENTNEYLAPAYSLLGFNPYDHSVLPKRIVAIGQASGSRVMIDLLSSIIGVPVYQSVALSPTTYSTVFLGNQLAITPAALGSCYKAAWTYLRQFNLNQSYEDFLGERNIQRSKRLRSSETRNTSAPIILTSLTRLDTSEASAQSAQPDQRGTAGFSSTNAASPIWNQDASSPELSNEPAIPIVSILTDSKDVEDGLVKVAEPDEDSVAVSLKLILSNIAPGSKGTVDKLRSLQDLKSVYGGEYFEMNKRPFTDFSAYA
The following text describes a protein:
Function:
Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably involved in the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAIYHQHTYNKWLILILLLVSVFVMMLVSLNLGSSDMSLSDVFFAFIGQGDPKETVIIWQLRMARVVAALLTGAGLSLAGCVMQNNLRNPLADPYILGISSAAIFGANIAIIVLGAGSVIGISTGGSVAINNPYTVTICAFVSSMSAMLIILTLAKLRGFTPEAIVLAGVALSAIFYAGTIIVQYFATDITLSAAIFWTFGDLGRVSWKEILILNVVVMLTTAYFFFMRWDYNALANGEETAKSLGVKTERVRFLGLLTATLVTSVAVSFMGMIGFIGLIGPQIMRRIVGEDHRFLIPASALAGSAILLASDTLARIVISPVVLPVGAITSLLGGPMFLFILMKGVRRA
The following text describes a protein:
Function:
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Sequence:
SSADFYDVEIMLMLKEGRIIFSLDFSIEDAFTELRKKGLAAATKKSSRVAAEGLLGLAHFEKGAAVIEINSETDFVARNDLFQSLVLSVAKAASTLEASVLSKERSFMFGNFQLVNVKLDHASITRELCVRDAVSEVAAITGENVRLRRALYMSSQRGIVSSYLHMSPASGLSRLAGLVSLEVEDDQEGSHSETLKSLGSSLAMHVVAARPLFLSKELVDSEVLEHERNICKAQASTAGKPENVVQKMVEGRLAKYMEEVVLLEQKYVADETKRIKVLLKETAKEIGKTAKIEGFLRIEVGEGIEK
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.
Sequence:
MEFEKRKKATLATMTSSEPDKSPKGDIDTPLIPLLQTLNSHPSYFTTSSCSGRISILSTPTAAATTAVKKKAKGGTWVFITHEPADPFSVQNLIFPPNPTQNDIQENLVFRFEPLIIAVECKDVLSAQKLVSLAISCGFRESGITNVSSKRVIVAIRCSIRLEVPLGETCKIMVSKEYLNYLVGIANEKMEANRKRTDSFHDALLRNEFIARPEISTGSGDCEFLNLNQDLGDKDCSMVTAGLEDIQLTSEIKDGASNGVPELPIKPMVITGEPVEKLHLWGHSACTLETTKNPKSVFVFGGFGGVGRHARRKDSWLLDSVSGQLQLVDFSSTPSPRLGHTASLAGELMFVIGGRADPGNVLNDVWVLNTTNNDWKQVLCTGIGFPHSHRHASAVIGSSLYVFGGIQNGSISSGMYRLDTQNLTWEEVVVQGQIPSPRHSHTLVAHGAQLFMFGGYDGSKALGDFYSFDIHSCTWKKEKMVGSTPYARFSHAMFVYKNYIGVMGGCPIKQHYQELSVLKVGSSVWKRIKLSSVGEDLFVRSTTSVVGDDLVIVGGGASCYAFGTKFSEPMKLNLLSLVSFAEPFNETEDQSNIDLKTMVPLRWVLRVDKKHAKPAKDILKKFGWLDAERKVYTQENGVHVCFPITKEFVALYQNKKPDINGVVNEVSNLNLQEILKVVSSARALDLLAALGATTHADHIVKVKKASSSPLKVMKDAVASLLNRHNLPTTLLEQLPTRWERLGDIVVLPMTSFKDSVWDTLGKELWLTVADSLGATRLARQGKVSPTGTRDSGLEILVGVNGWVDHRENGVLYSFDATKCMFSWGNLSEKRRMGQLDCKQEVIVDLFAGIGYFTLPFLVKANAKMVYACEWNPHAIEALRRNLEANGVADRCVVLEGDNRATAPKGVADRVNLGLLPSSEGSWITAVKALRSEGGMMHVHGNVKDSEEDSWTEQVSKSIKEISRSEGYNWDVSVEHVERVKWYAPHIRHLVVDIKCKQIDS
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSAEPTDPVMEKRDKPQLSDRILSLTLEIIYILTGEGYSVTKKSGDDMPLPQSCTDCMLGGACRHHVTSPTVPPPPGSVIQKENAKKILELISNIIQLLTGEESGELYREGIKENWEQLSPLDPEEKFSIKSETDSFAENKPDKTEAEEADSWGAVNPPNPDISPNDPQTLTTFVSYGTYREPASWEEDNDSDSSIHSFTEHMQGSDPYTDIKGPRLHKSLAANHGSDCSNEEAASGDKRDSFDPKTEETQGSATQTQVCSLNTGLISNEIKEEAASWGGELTLPAGRRAFSCSECGKCFGFLSQLNRHFKRHTGEKPFSCSLCGKSFSRQNNLKTHFITHTGEKPFSCSQCGKCFALQSHLITHFTIHTGEKPFSCSECGKCFSLQSHLKTHVIIHTGEKPFSCSQCGKCFGRQSSLKRHFKVHVDKPPLR
The following text describes a protein:
Function:
SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus, cis-Golgi network membrane. Golgi apparatus, trans-Golgi network membrane. Melanosome.
Sequence:
MVLLTMIARVADGLPLAASMQEDEQSGRDLQQYQSQAKQLFRKLNEQSPTRCTLEAGSVAFHYIIEQGVCYLVLCEAVFPKKLAFAYLEDLHSEFDEQHGKKVPTVSRPYSFIEFDTYIQKTKKLYIDSRARRNLGYINTELQDVQRIMVANIEEVLQRGEALSALDSKANNLSSLSKKYRQDAKYLNMRSTYAKLAAVAVFFVMLIVYVRFWWL
The following text describes a protein:
Function:
Required for the correct positioning of the cellular division plane by delimiting the actomyosin ring assembly at the cell equator. Overexpression causes cell lysis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Enriched at the cell equator during mitosis.
Sequence:
MSEQHSLNPFESGSVTASDVAAAKSGAEDLVNTLTAHTVHPSTELPSATSFPSALPNSENPVIQNISSSSSEPHHTSQSTPGETSSPVCPVSGAHGGADKKCPALEAGCPFTNTTKQNVDPEISNALWSVLTWKNTSCSFSTLMSILALVYVPSWINLPRLFFRTFRYVFLITSIIEFGGLFASNGKRGVLSHFRSSYITCDSKALDRIVNSIVDIFNVMLIQFQRILFAESPILTFTASVAAFIEFFLSGFLSYKSLFVWNVLFAFILPRLYVCNERSIKHLVASLERSGDKLKKQATETINTTVNK
The following text describes a protein:
Function:
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.
Sequence:
MLSCDWFQTSSGGSAEVMAENHIMSSEAPPKSNQGLHFRTNCRMILNLLREKDSSVTFSPEQPLTPVTDLAVGFSNLSTFTGETPKRCLDLSNLGDETGPLPTESPDRMSLGKVESPKTQFVQFDGLFTPDLGCKAKKCQRGNMNSVLPRLLCSTPSFKKTSGGQRSMSNKENESELFKNPNCKPVALVLPQEAVDSQFSPAPEDKVDISLDEDCEMNILGSPISAAAPCLEGPHDDIKMQNLDGFADFFSVDEEEIENPSGAVGNLSSSMAILLSGPLLNQEVEVSNVNNISLNRSRLYRSPSMPEKLDRPMLKRTVRPQDSETPVRIKRRRSTSSPLQPEEENCQPRRRGTSLKKTLSLCDVDISTVLDEDCGHRQLIGDFSKVYALPTVTGRHQDLRYITAETLAALIHGDFSSLVENVFIIDCRYPYEYDGGHIKGALNLHRQEEVTDYFLKQPLAPSVAQKRLIIVFHCEFSSERGPKMCRFLREEDRARNEYPGLYYPELYLLKGGYKDFFPEYKELCEPQGYCPMHHQDFREELLKFRTKCKTSVGDRKRREQIARLMKL
The following text describes a protein:
Function:
Probable phosphatase.
Sequence:
MPAFRIKSKSNSEYLRLHDLHTCRKSAKTSKSSQTQVKTFQLETELDTFFQTQQNASSNKEVSVCNSTLAGFDGPYIQLLNASPFSLDPVSIRRSDILSETNPSNLETIFSPDLEHRASLLKSANYIDEAKYEGTRLPHLVADGADNATCISSEYQTCGLSEFYISDSIHEGAKLPHLVADETDDTTCVSSEYQTCGLSDFITDCIHEGTKLPHLVADVIDDATCVSSEYQTCSLSDFYISDSISGCPFDNSVEVTDVITATCPINEYMNSDIMIDMGEGYMILPFLERTVETGDDDDSVQETMMNFNEASLYLAVHPENENKCNFGNLEEIECFDQLLVFNRLPDLPQAVSSILSPQKAQERMPVTLVLDLDETLVHSTMEQCDDADFTFPVFFNMKHHTVYVRQRPFLQMFLDSVAQMFEIVIFTAAQSIYAGELLDILDPDRKIISKRIYRESCIFSDGTYTKDLTILGVDLAKVVIIDNTPQVFRLQVNNGIPIESWFGDPLDHALVQLLPFLETLVYVEDVRPIIAKKFSNNE
The following text describes a protein:
Function:
Necessary for the splicing of pre-mRNA.
Subcellular Localization:
Nucleus.
Sequence:
MDLHSRISSDRGSSRSRDYGSAGEYNSYSNDRRRDYGDERRRRRRDDSEYRGRYRDDDRRYSSGRDRDDERDRKESRYSRDRHDRYDRNERRESRYSSRRRSRSPSYRSRPLNIERELEELKNVVPLNQWKRKRSMWDMKPPGYENVTADQAKMSGLFPLPGAPRSATADPEKLAAFARSTAGSIIAPPPPIQPGASRQARRLKVKELPAEFEVEDLKNVFEESISTSSFHKDRDTKHVTAIYPCKTERYAIIELATPEDATFIWGARKLKFKNETVLIDRLEGYIVPQISSEVAQKRPKNDLNQKVLDSADKVYIGSLPLYLNEDQISELLKPFGELQSLFLAKNSADMTSRGYAFCEYISSESATAAVQGLNNMEFGDTRLMVQFACVGIQQPVPSPRSVGMAALIELSKSSTEAAPTRVLQIHNLLDADETLDTEDYEDIRKSVQNKCNEYGQVLDLKLPRETSSSDNTSAPPGVGVTFVRFGSIKDAANALQHMSGLRFDDRSIVIAYYPEDCYKANAW
The following text describes a protein:
Function:
Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.
Sequence:
MSTDKISVLLNWHATPYHLPIFVAQSKGFFAKEGIKVAILEPNDPSDVTELIGSGKADLGCKAMIHTLAGKARGFPIKSIGTLMDEPFTGVIYLEGSGITSDFRSLKGKRIGYVGEFGKIQIDELTKYYGMTSKDYTAVRCGMNVSKAIIEGTIDAGIGLENIQQVELEEWCKANNRPASDVKMLRIDELAELGCCCFCSILYIANEDWLKDHPKETAAFMRAVKAGADAMFADPRGSWAEYCKVKPAMNTPLNRIMFDRSFNYMSQDLINVSRDWNKVTNYSKRLGIVPEDFVSNYTNEFVQWEVAPEGGEAEGLAKQQEMKTLQAHVAEHGGVLQAVTA
The following text describes a protein:
Function:
Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO. May play a role in preventing light-dependent degeneration of retinal photoreceptor cells.
Sequence:
MPKVIQQTSGRVAIYLGKRDYIDHVNWVEPVDGVVLVDPELVKGKKVYVSLTCAFRYGQEDIDVIGLTFRRDIYFSQTQVYPPEETVATPTKIQDSLMKKLGSHAYPFVLQFPDYLPCSVVLQPAPQDVGKWPEMLIFNFWSWPEILICNFWSLSPRNSVRLLIRKVQHAPADMGQQPRTETAWQFFMSDKPLHLTISLSKEVIYFHGEPIPVTVTVNNNTEKVVKKIKVSVEQVTNVVLYSSDYYVKPVIQPNSSLTKTLTLIPLLANNRERRGLALDGRIKHEDTNLASSTILHAELPASCLYSGVSTSLCCPDHFSTQTFRPHCPIPQEPPVVAHPPPHRTETPYHRREAASARRSVAQWKEPGLGSQRS
The following text describes a protein:
Function:
Positive regulator of hypersensitive response (HR)-like cell death. May be involved in potassium ion channel regulation.
Sequence:
MGNLCCCVQVDQSTVAIREQFGKFDSVLEPGCHCMPWFAGKRVAGQLTLRLQQLDVRCETKTKDNVFVNVVASIQYRALADKASDAFYKLSNTRSQIQAYVFDVIRASVPKLHLDDAFEQKDEIARAVEEELEKAMSAYGFEIVQTLIVDIEPDEHVKRAMNEINAAARLRAAANEKAEAEKIVQIKRAEGEAEAKYLSGLGIARQRQAIVDGLRDSVLGFSVNVPGTTAKDVMDMVLITQYFDTMKEIGASSKASSVFIPHGPGAVRDIATQIRDGLLQGSSVAKH
The following text describes a protein:
Function:
Catalyzes the radical-mediated cleavage of tyrosine to 2-iminoacetate and 4-cresol.
Sequence:
MSFVDHFARIERDKLLLALYSCTAADVERALVQPEGNLQSLLALLSPAAEPYIEEMAQRSAALTRQRFGANIGLYLPLYLSNLCANECDYCGFSMSNKLKRKVLNEQELAAEIAIIKSRGFDSILLVSGEHETKVGMDYFQRVLPLVKQQFSYLAMEVQPLEESHYRKLVEQGLDAVMVYQETYQAETYAKHHTRGKKQDFAYRLATPDRVARAGVDKIGLGVLLGLDDWRLDALMMGYHLDYLERHYWRTRFSISLPRLRPCTGGIAPKVHLTDLGLVQMICTFRLFNQQLDISLSTREAPSLRDNLLPLGITQMSAGSSTQPGGYQVPDSQLDQFEISDDRTVEQVITQMRLKGFNPVFKDWESAWIVPKMRV
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDDCFFILFTLIMTSCALLNPSDHQQHFLKDDFVTNSQILNPEMNYSKDQEETEPREIKEEEPEPRQIKEEEPEPSHIKEEESDPPQLQGKCLESLHITEELDVNKRKGIIISEPHRLDLTLKPVIKLHRIDVCLLRTNKKVDLREPQSSTEQLLTNNRSEALNQDQKRNFEHLRSSPSVKLKLRKQQNKKSYHNMDVDSPSPAKTHCKTGTGKKSSLRGHGRRQKSQSTSLRSRQGGDNTFKKTSKNKYLCTVCGKHFARHSLIAHRRIHNGEKPFACETCGKRFTQRGNMLLHTAVHTAEKPYSCDTCGKKYSRNESLLRHNRTHTGERPFTCKTCGKGFARSEVLSAHMSSHSDERPFACKTCGKRFSLRNTLATHMKGHTGHKAFSCKTCGKQFTRKCSLLLHTKIHTGEKLFACKLCGKRFRQKSHMLGHVRTHTGEKPYLCKTCGKTFGNSTLLLRHIRTHTGERRYSCKLCGKKFKQSGSLGVHMKTHAGEKPYSCGTCGKTFSRQDNLTEHLKIHTGERPFSCETCGKRFSRKRCLSSHMRIHTDQRPFLCKTCGKRFRQISVLTCHTRIHTGEQPYLCKICGRRFSRSGNLSQHLRVHTGEKPFSCKSCGQSFSQRGNLKYHLKRHL
The following text describes a protein:
Function:
Transcription factor that binds to DNA at the consensus sequence 5'-CAG[GC]TG-3' (By similarity). Positively regulates the determination of retinal ganglion cell fate and formation of the optic nerve and retino-hypothalamic tract. Required for retinal circadian rhythm photoentrainment (By similarity). Plays a role in brainstem auditory signaling and binaural processing (By similarity). During retinal neurogenesis, activates its own transcription, as well as the transcription of CHRNB3 and BRN3.
Subcellular Localization:
Nucleus. Perikaryon. Cell projection, axon.
Domain:
The basic motif confers specificity for the CHRNB3 promoter.
Sequence:
MKTCQSSHLDSGVESDIQCRSGSGCVVKCSTERMESAAKRRLAANARERRRMQGLNTAFDRLRKVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERYSTEREWINLHCEHFHPESYHHYTGQKVATDSDPYAQRIFSYHPEHFQIAN
The following text describes a protein:
Function:
May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8.
Subcellular Localization:
Nucleus.
Sequence:
MALLGKHCDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSALSKLNTEVACVAVHNESVFVMGTEKGRVFLNTRKELQSDFLRFCRGPLWNDPEAGHPKKVQRCEGGGRSIPRSSLEQCSDVYLLQKMVEEVFDVLYSEAMGRATVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQDTKALVEMNGISLLPKGSRDCGLHGQASKVSPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPTCPLTPSDLGLGWPVPEPHVPSTQDFSDCCGQAPAGPAGPLIQNVHASKRILFSIVHDKSEKWDPFIKEMEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDPMKLEPASPPEDTATEVCRDSMLDLAGTAWSDMSSVSEDCGPGTSGEIGMLRPIKIEPEELDIIQVTVSDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWQEERPAEESPGDVIRPLRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTDGVKEPVMDTQENYNTRLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTRPFQGLIPKPETKILTTGHEAGKTTRPRRPQQDSWQPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKARDHVRMVIINQLQPFTEVCNDPKVPDEDDSNKLGKKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKARDHVRMVIINQLQPFGDVCNNAKVPAKDNIPKRKRKRVSEGNSVSSSSSSSSSSSSNPESVASTNQISLVQWPVYMVDYSGLNVQLPGPLDY
The following text describes a protein:
Function:
After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol.
Miscellaneous:
MISCELLANEOUS: Present with 8680 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MAPIFRNYRFAIGAFAVIMLILLIKTSSIGPPSIARTVTPNASIPKTPEDISILPVNDEPGYLQDSKTEQNYPELADAVKSQTSQTCSEEHKYVIMIDAGSTGSRVHIYKFDVCTSPPTLLDEKFDMLEPGLSSFDTDSVGAANSLDPLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDGVSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVFEPTFPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNTKTHQLSSPCLPPKVNATNEKVTLESKETYTIDFIGPDEPSGAQCRFLTDEILNKDAQCQSPPCSFNGVHQPSLVRTFKESNDIYIFSYFYDRTRPLGMPLSFTLNELNDLARIVCKGEETWNSVFSGIAGSLDELESDSHFCLDLSFQVSLLHTGYDIPLQRELRTGKKIANKEIGWCLGASLPLLKADNWKCKIQSA
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.
Sequence:
MQSTKAQISKPAPDWEGTAIVDGEIKTIKLGDYKGKYLIFFFYPLDFTFVCPTEIIAFSDRVAEFKKINAEVVAASVDSHFTHLAWLNTHRSEGGLGKLNIPLLSDLTHKISRDYGVLLEDLGHTLRGLFIIDPKGILRQITMNDLPVGRSVDETLRLVQAFQHTDEHGEVCPAGWEPGKDTIIPDPKDKLKYFHKTSKAKG
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
Sequence:
MWWGSLHSSGLLRASRLVRALGPNRAAFAAAARAEEGARNSARGSSSCAMRAVTPLPPSQLRRAGAMEASACLGRSNASPRQQNDASVSMSTSAPSAFSAIQFLTLCQSLKTTKRTGWVNHGLKESESIADHMYRMAIMALIAADGVPGVNKDRCVKMAVVHDLAEAIVGDITPSDNVPKAEKSRREREAMDKMCAMLGGGDAAQEMMELWQEYENNATPEAKLVKDFDKIEMILQAQEYEQEQGKDLEDFFRTTRGKFQTDVGKALAAEVVKRRTTSSIESNSSEASN
The following text describes a protein:
Function:
May be involved in response to oxidative stresses.
Subcellular Localization:
Plastid, chloroplast. Mitochondrion.
Sequence:
MLNKLTHGVFTYRASLTAMLSSSTSAGLSSSFVSSRFLSSGIFSSGASRNRVTFPVQFHRASAVRCFASSGGSDRIQVQNPIVEMDGDEMTRVIWSMIKEKLILPYLDLDIKYFDLGILNRDATDDKVTVESAEAALKYNVAIKCATITPDEGRVKEFGLKSMWRSPNGTIRNILDGTVFREPIMCSNIPRLVPGWEKPICIGRHAFGDQYRATDTVIKGPGKLKMVFVPEDGNAPVELDVYDFKGPGVALAMYNVDESIRAFAESSMAMALTKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKQKFEEHSIWYEHRLIDDMVAYAVKSEGGYVWACKNYDGDVQSDLLAQGFGSLGLMTSVLLSADGKTLESEAAHGTVTRHFRLHQKGQETSTNSIASIFAWTRGLEHRAKLDKNEKLMDFVKKLESSCVNTVETGKMTKDLALLIHGPKVSRDLFLNTEEFIDAVASKLKTQFKELPLV