lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MASSSTAATSAAARGTLLSVLLRLTSFLLSQLTVRHVSVSTLGKANIVLELLLGTALFVGREGFRLGLTKNIAGVANGSSGEEEKEDANGASPGDGGVPTKRKFQQHESYLDENKKENRQRDEQQMQQQRIINVSWLSVPTGAVMSILAVLMHLYSCSSNNNTSNANASEMMDYKLAGILYCIASFIESLSEPLVIRCLQEMDVTTKAKAEGAALVCKAVACFGMLHLTSSVWFWEAMKTIATRLELGVGGSGGQVCFAVTAFGVSQLVYAITFTTIMFRKARATKDGIRWPKRIHPFVSNPYRSDDTTAHQTQSGTTPLTQNFDLHTLHLILIFTLQGLFKHALTEADKIVLSTLAGSYDQGVYALASSYGGLAARLLLQPLEENARLLFSRQGALLAQQLQDATTTNGSREKDTQQYEKKQTIGGGPNNLLSDLESTYCFLLRAVLYIGLIFATIATNYTSLLLRILAGDRWGSNSEASAALSAFCVYTAFLALNGTTEAFVYGVARSGRDVGKLGVAHAVVGGIFALISPGLVRSKGAVGLVTANCVCMGLRSAYSLYYARTYFAKAEEALSGGKNDRISMISQIAPHPVVLALFSMAYAVTKSSRDVLYDGALADGAVWTVAALTHVLVGILSLALTMTVSLYFESDIRASFPLLDGNDLVPLPFNVVECSSEEHGCESSALHSYREDSNGWQSSCQGPTPHTLVLKIQHHDEERMVHRLEILCHEYKVPEKVEIILASGCADEEIPSLFDECESILHLGYITMDPNERSDYQDRELKSIPIGKPADFIRLVIPRCHKNSLNPDNQVGIVGIKVLGVEAAIDDVSIEKEEEIVVVESENLILPTTTDEITEAPILNVALSPPLKKLHNILTPVSSLPSRIKHELDPKMQQSVDRLERFKKERAALEDFDTAAKAKEALGTVYALLITYKESESKMREAAAIEEYAEASRLKTERDTMRKAAMQALSEVEQTFIEQREDAVEVLSISTIKDESFVSQRSARSIHPFSESEQYHEMGNISNTCSQSGANETCLEEHEEDRNDSGGEESEDDSNDSHPLSGVNDAEELPTPEEIDYESVDVSSDLVKKVDHIFGEYRAKCFFSKNWQLREAALAKMTLLIPSVCGGSSAEECAEILCNIVVRSIGDKNVQVYLAGLILLDESLLQFERSELPQTKITPLLSKIIIELLGKLAESKTKVVDSAELSLLSIAHSSCVDISYICNAGTKRVKSTDSKGGRTVKARLQFMDNLIAEFGDEVGWKRVLEFAKGKVA
The following text describes a protein:
Function:
Putative transcription factor that coordinates gene expression underlying the differentiation of the pedicel abscission zone. May also be involved in the maintenance of the inflorescence meristem state.
Subcellular Localization:
Nucleus.
Sequence:
MAREKIQIKKIDNSTARQVTFSKRRRGLFKKAEELSVLCDADVALIIFSSTGKLFDYSSSSMKQILERRDLHSKNLEKLDQPSLELQLVENSNYSRLSKEISEKSHRLRQMRGEELQGLNIEELQQLERSLETGLSRVIERKGDKIMREINQLQQKGMHLMEENEKLRQQVMEISNNNNNNNNGYREAGVVIFEPENGFNNNNNEDGQSSESVTNPCNSIDPPPQDDDSSDTSLKLGLATLLRLKRSKARCGYFCMLLEEGEKKK
The following text describes a protein:
Function:
[CLE21p]: Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance. Regulates the transition of protophloem cells from proliferation to differentiation, thus impinging on postembryonic growth capacity of the root meristem; this signaling pathway requires CRN and CLV2.
Subcellular Localization:
[CLE21p]: Secreted, extracellular space.
Sequence:
MLILSSRYAMKRDVLIIVIFTVLVLIIISRSSSIQAGRFMTTGRNRNLSVARSLYYKNHHKVVITEMSNFNKVRRRSSRFRRKTDGDEEEEEKRSIPTGPNPLHNK
The following text describes a protein:
Function:
Regulatory protein of the TOL plasmid xyl operons. XylS activates the xylXYZLTEGFJQKIH operon required for the degradation of toluene, m-xylene and p-xylene.
Sequence:
MPDETSGEHTHFWRAAELGGVELLHARYVEQRFAPHVHSSFALVIIEQGAQRFRHRGGEHLAPLGSMVLINPDEVHTGSKAHDAGWLYRGYYPEMEQIDGILDELEIHHGGVPRFADSVIHDQPLARAFVHLHRLLAEHADSLETQTRWRETVLALFRRHARLPEAPKAGQEPLAVARARELLAARLLDPPSLEELAAAVNLSPFHFARVFRRATGMPPHAWLRQRRLEQARALLKSGRAPLEVALELGFADQSHLGRQFKQAYGVAPGEYRSACARSSLTIYE
The following text describes a protein:
Function:
Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
Subcellular Localization:
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.
Sequence:
MRLHRLLLVFLLMVLLPVPGLLKNIGNSVSCLRNKGVCMPGKCAPKMKQIGTCGMPQVKCCKRK
The following text describes a protein:
Function:
Transcriptional regulator. Acts as a transcriptional activator that binds to purine-rich GAGA sites found in the promoter of many genes including insulin I and II and islet amyloid polypeptide.
Subcellular Localization:
Nucleus.
Sequence:
MDPSNWSSFIFQGHAQNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVVTAPPAPAAASTVDTAALKQPPAPPPPPPAVSAPAAEAAPPAAAATIAAAAATAVVAPTSTVAVAPVASVLEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSGASGGGGEAGAGGGTAAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVHKPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVPCHVCGKMLSSAYISDHMKVHSQGPHHVCELCNKGTGEVCPMAAAAAAAAAAAAAVVAAPPTAVGTLSGAEGVPVSSQPLPSQPW
The following text describes a protein:
Function:
Involved in splicing regulation. Facilitates post-transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS. Does not participate in the production of small RNAs.
Subcellular Localization:
Nucleus.
Sequence:
MCGQRSLLNIPSPIFFLLHAAAAAAAGVDQLIRLELNASSARVRRPENPRHRRHPHDRHGTRRRQSEHHQTKDAGRAKQHGAEYYEQRRGYEEESHSNREDDSHQRHQRAADDNSGDGYPSYSVANLDEIRATMKLVRFLMKLNNETVSIEIKNGTVVNGTIIGVDVSMNTHLKSVKLTPKGKNPISLDHLSIRGNTIRYYILPDSLNLETLLVEETPRVKPKKPIAGKPLGRGRGRGRGRGRGRGR
The following text describes a protein:
Function:
Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
GYREHAWGHDELLPVSQRHSEWFKLGLTLVDALDTLYIMNLQSEFKEARDWVANSLNLDQNIDVNLFECTIRVLGGLISTHALTGDQMFLDRAHDLGDRLSYAFNEHSGVPFSDVNLGTHHAHKPAWGPDSSTSEVTTIQLEFKALSHFTKDRKYFDRVTKVMDHVRQIKPADGLVPIFINANSGRFSGNTVTLGARGDSYYEYLLKQWLLTNKKEDVYKQMYEEVVKSITDQLLTRTKDGRVYVAERLNGRKSPKMDHLVCFYPGMLALGYLHGMPREHLEQAKEVAKTCYDMYSTQPAKLAPEIVHFHDGRRHQSPSMYVKPADAHNLLRPETVESLFILWRVTKDPIYREWGWEIYKAFEEHCRVETGGYSSLTSVLTSKPAFRDKMESFFLGETLKYLYLLFEDDDNFLPLDQWVINTEAHPLPIFDPPS
The following text describes a protein:
Function:
Probable component of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation.
Sequence:
MAATLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRGGGAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWPFESV
The following text describes a protein:
Function:
Probable transcription factor involved in response to fluconazole, LiCl, and copper.
Subcellular Localization:
Nucleus.
Sequence:
MSMSDIQQRPQIPTTTTAAVAAAASTNVNTGAATTSTATTGNTPTTTPTSPIENISKVPVKPSVDVPVKPKLEQQQQQQSEQSSKPPPPPPEQQQQHQLPTPPIKPPKTGTTSSSSSTTTSSATSSKISMSGPVCGNCQTQTTPLWRRDETGQVLCNACGLFLKLHGRPRPISLKTDTIKSRNRVKQNGSNSQSSKSSGANTPELKSKEGKSGKKSPKSKKKSLGNGNGNGNSSHDHNTLTPLLPATSNNTPTFKSTTSQSQHQQNQNHHHQHHNHHHHLPNHVLQTHQVPLHYPSSTPTQFAPGLQRITSPLLLSTTSSSSSIRTEPNNNNTSKLTPIQAAAGALENMSNELGPSATFKKGNNINGISLMNKTKKDVSSINGSSTSLSSSSASSSIFSSVAPSTSSSSSLSNGTTINNPAPKLPTLGSKISSPSSQPFTRSTTPLQTLPPLHKIASHESSLPPLHNISTYNNNNSGGGADGGQQSMANYSQTNRSPINGNQDNNNNNNNNNNNNNNGNNNGNNNSNNNGNNFTASAHEVTLLKTRISELELVNDLYRTRIMELEAMEQAARLRENSMKKRLDEVMNLQINYQNLLNNNGGMSSQTQPQPSQQPQQAGQYYSNNNNNNNNDQGSQSISPNVSITGSTTITSPNSRSKIISETTPTHHQQQQGGVGAGDNESIILPPLKRNRTDELTDANGNGNGNDNKKVKI
The following text describes a protein:
Function:
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
Sequence:
MNEIDKSVDIGFLRILDVIKKVTTPKGGIEILRTLIDFTPKIENALNLAAKSHKGQYRKSGEPYIVHPICVASLVAFCGGDEAMVCAALLHDVVEDTPCKIETIEQEFGQDVANLVDALTKITEIRKEELGVSSQDPRMVVSALTFRKILISAIQDPRALVVKISDRLHNMLTLDALPHDKQVRISKETLAVYAPIASRLGMSSIKNELEDKSFYYIYPEEYKNIKEYLHKNKQSLLLKLNAFASKLEKKLFDSGFSHSDFKLVTRVKRPYSIYLKMQRKGAVNIDEILDLLAIRILLKNPIDCYKVLGIIHLNFKPIVSRFKDYIALPKENGYKTIHTTIFDESSVYEVQIRTFDMHMGAEYGNSAHWKYKAGGVDHEDHHEGMRWLQNFKYHDSDLKNDPKEFYELAKNDLYREDIVVFSPHGDTYTLPVGAIALDFAYMVHSDLGDKATDAYINSKKALLNQELRSGDVVKIIKGDKIIPRFIWMDQLKTSKAKNHLRIQRRNRLKEVDTKSMINILATFFGRSVFEDMDLKDYKNFEERLTDCGVETTLTEAMKSFENLAKLTEEIENKVFSLKEDAILEYQEMSLWTRGLRYLGFKTNVLNFLAPNRQWQCKELEHFSVCSSNALEIKQVLLNDCCYPKYGDEIIAIVTDLKDPKAIAHHKFCKKAMAEVDAKVPMVYIEWHKRDRTIYKMMFYLGEKKSVLAGLLTFLNRNECNIVGVSYLGYKDKYSSHCEVSFEIATDKADWIRALINRKYQDRIVELSSLDDAYES
The following text describes a protein:
Function:
Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
Sequence:
MRTWIEIDKENLKYNVLKLKEIANNKEILGVVKANAYGLGSIEIAKILKEVEVKLFGVANLEEAIELQEAGIKDKILILGASFEDELVEATKRGVHVAISSMGQLQFLVSKNLNPNIHLKFDTGMTRLGFEVDDAEKVIEYCKNNNLNLVGIFSHLSDSDGNTIETKNFTLEQIEKFKKIVNSLNLEYIHISNSAGITNFHNDILGNLVRLGIGMYSFTGNKKTPYLKNIFTIKSKILFIKKVKKDSFVSYGRHYTLPADSTYAVLPIGYADGLKKYLSKGGYVLINNHRCEIIGNICMDMTMIRVPKEIENSIKIGDEVTVINADILDNLNIPELCVWEFMTGIGRRVKRIIV
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MDKNVLRLIFFVAVSAAAVSGNPSVLTSHDKITLTFKAGKVGPSRPIEIRLLRDGAPKATENFKLFCERKEKGYVGTKFHRVVPGFVVQGGGIDGKSAINEDGSHFGKEFPELQFPGAGWLSFAKTNVPVSMAEQFFFTTGCEDRYGSLNDGFTVFGKVVKGMDVVKEIECIQDESKARGKCTHSVVYQIASCSHVFETVHNVTVEDTLGLACSNGKDRVTKNYCDQLRQNNDNLCIGRRDADCFTRMDLKEECECNRKIGQQPAQCRPQQQRRPQQRRQRQPQRRRQQPRQRYRRRRR
The following text describes a protein:
Function:
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Propionate is the preferred substrate but can also utilize acetate and butyrate with a much lower affinity.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MKPSWLQCRKVTGAGTLGAPLPGSPSVRGAGVARRALVAGFGGRGCRALTTSSGGGEYKTHFAASVADPERFWGKAAEQISWYKPWTKTLENRYPPSTSWFVEGMLNICYNAIDRHIENGQGDKIAIIYDSPVTDTKATISYKEVLEQVSKLAGVLVKQGVKKGDTVVIYMPMIPQAIYAMLACARIGAIHSLIFGGFASKELSTRIDHVKPKVVVTASFGIEPGRKVEYMPLLEEALRIGQHKPDRLLIYNRPNMEKVPLMSGRDLDWEEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKGVVRPTGGYAVMLNWTMSSIYGLKPGEVWWAASDLGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYFRVLAEHGVAALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTLFVAGERCDVETLEWSKKVFRVPVLDHWWQTETGSPITASCIGLGNSKTPPPGQAGKCVPGYNVMILDDNMQKLKARSLGNIVVKLPLPPGAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVINVAGHRISAGAIEESVLSHGTVTDCAVVGKEDPLKGHVPLALCVLKKDVNATEEQVLEEIVKHVRQSIGPVAAFRNAVFVKQLPKTRSGKIPRSTLSALVNGKPYKVTPTIEDPSIFGHIEEVLKQAL
The following text describes a protein:
Function:
Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.
Subcellular Localization:
Nucleus.
Domain:
The JmjC domain mediates the demethylation activity.
Sequence:
MIGATSFLNHSGPRPPRYRTPSPPRRAVEPISPFTTTTDFRASWIDRGDSQAASYDRDRVTSNNDVYSSTNRGSHGRTSHGRSSSTIDTLATIALATSPTFAPLSYRPPSQDPTPAMPLFPSQSIESTERPAKRPRSEKSPSPLHQPQTTVAPDANPSSTFDSMKTDAELLLNFARPSNFQPAAFYPSKRVSIDESYHPHYGEEPKSHFRAGLGSTYILPDGEKSAYHTSANTAFPASRMRSQSDGSAFISRPVIQGVRPNTSSSTLPPIVWQEEEGNAKTGPGPPSTKFPGAETRYENSVFTGIDTGADRASLDVPPRGDDDTESDENNQANCAACNLVRIPVDSEEQGDVTWISCDGCKQWFHIVCAGFKNDREIRTVDKFICRRCRPIHGQTTFVRKSSRARTAIDYAGLNQGLVKAASDSLEHHYIEPIREGKIRFLPDNFPRMRPELVTAEYFERGSGMTEPIVIPAHLNTRDSIPIVDPEFDSLVQEATSQEMFDELLEHLPEEGKDFETVIDCGQDQLDMVVPQGLTVRAVAELYGPEERVEVIDVKSQQGEDKRWNMQKWADYYESTGSKVVRNVISLEVSQSKLGKLIRRPKIVRDLDLQDAVWPEELKAIGDYPKVQFYCLMSVADCYTDFHIDFGGSSVYYHILKGKKTFFFIPPKDKHLKKYEDWCNSPAQDSTFLGDQTKECYRVDLSEGDTMLIPSGWIHAVWTPTNSLVIGGNFLTRLNYGMQIKVAKIEKDTKVPRKFRYPFFQRIQWYTALKYLEDDPIPQSVLNAFAEDENYRFHRAYPIYYEFGERENKAPAGDPYHNSRFYSQAELEGLPDLAKYLLRTALIASGYMVEGVTMDARNAVKRSIPKGQGDPIDTVRKFGIWVAWKRGNEKAPQWTRPGVVESNAKLSLTEKKPAGRPSRRSERNAEGQRMYAERQAVQRPLEQPPDLTNGLSSEESSSAPSTVEIPQSTVISTLPGTETKELKEEIAQKPRSIHRSSGLGPKRVACDACRKRRIRCRHKDEHNDTISAKQTTFGTFPAGVQSSLAHDAASALNSLAAIASEAGFQDAANGHGLERLEGSGNYSTAILSTPNAATSKVHDGSPEGLNTGKKGRSKACDDCRKSKRRCIHDEYGRIDPIKAQERSKPRATASAKRPRPPQEEDAAFTLNKRPKQESTSPVARPASLFRAEGDMSHTQRPVDLEASSYFGTAHDHNGIAQTKLTSAVGQTSYASPPAFQSDTVVMEVAGQGVSKPTASLVSPPTSQADETDVPPEQDAEKDNHVVYYTPTTSSRHSSRQPRHVDRYVPESQPAKAVKTTHTPSKRRASCSGPTTARRVTPGAQGSSKKPASRPSSSHAKKGVSPVTEKKFDRMTTTSTSPGHKGAKRERTAIADDEPDAESLRLIRELQEQEFGLRKRTTRV
The following text describes a protein:
Function:
Together with PDP2, PDP3 and PDP6, interacts with MSI4/FVE and MSI5 to suppress FLC, MAF4 and MAF5 expression by regulating the function of the PRC2 complex and modulating H3K27me3 level, thereby promoting flowering.
Subcellular Localization:
Nucleus.
Sequence:
MYKTKLIPVMNEDAVIVQQTDSIQDPKVTPDDTVVDSSGDVHEAIDDDVEASSPMELDSAVTNDARVLESERSEKDGVVGSEEEDEIKSEDVLIDKDDESSEVKEEEEEEDGSDDQSSELGSEADEKELDLGLKEEKKGVSDYKSLLSEFDDYVASEKMGSGVSRALSYGFEVGDLVWGKVKSHPWWPGHIFNEAFASPSVRRMRRIDHVLVAFFGDSSYGWFDPAELIPFEPNLEEKSQQTVSKHFVRAVEEAKDEASRRSALGLTCKCRNPYNFRPSNVEDYFAVDVPDYELQAVYSVDQIKNSRDKFLPAETISFVKQLALAPQECDPDSLKFMKKKAVVFAFRKSVFEEFDETYAQAFGTKSPRSSVSTLEPHNRAPPRAPLSGPLVIAETLGDLKSSKKPTKVKVSKKKDKYLLKRRDEAGDKSVQFGEIEASSEASHIQGIDGSLDGDFGLQRRAPTLQTPMKDEKSGIVSMDFASSNTAIPGKEFSASKPSLDEEKGLAEKSKERMEERAAVLPEHGKSEAMASLKPKEEAGTDLGSAGSSLQPLLESHTSASEGKSSTGSVIKKVKVAKRSSSEMSSENPPSEPKKKKKKKKEPDSDHPVKRKNLYSGEAGAKKLSQLGSAHLQTYMEADVPQLLSHLQDLSLDPFHGLSVASFGTARKFFLRFRSLNYQKSLSVSSSDATVENARDTKPSKPVKTVKRTEDPSKAGKKRLSSDRQDEIPSAKKLKKTNQLKSMASEKKIIREAKDSIKPIREPSRVVQAKPARGQTGKKTAPSVKVVEPTMLVMKFPPGTSLPSAALLKARFGRFGLLDQSAIRVFWKSSTCRVVFLYKADAQTAFRYATGNNTLFGNVNVKYFLRDVDAPKAEPREPENTKEDDEPQSQWLDQAPPLHQPTLPPPNVNLKSCLKKPVDDPSSSSNNGNGNRAAVRVKFMLGGEENSSKANTEPPQVTMTLNRNSGPSSSSSSVPMEFVSKKFQNVVHHQQLPPSTLPPILPLPPQYTKPQQLPIKPVDHVEPPMPPSRNFRGPIPAVSAGDISHQMLNLLSKCNEVVANVTGLLGYVPYHPL
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MRNTARVPTPPGTIFYILRSDATGMFDSFYRLRYDQRILGRCLIDPRGWTIVHDFGQTCPGEDPRCISHKGTDYLLDNTWGSSSLIVPADNFRPCKLPSKGKNLSLISHGDELLCIEWLRPLTVLSTTESPYPDTWRRVRARKESPDYSLRGGTPGYKTPVDDRVYVGFGHRTTAGPKGEVKHNPFVWRLDVKSWQMSFAEVEAQLERAITDPTCVVQHDGRFYLQTVPRTTLANKDFGFNRHFKDMYTVKEEIGRGSFGRTHIAEAKSQKGGTVAVKIIPKSSMISEAAIMDVHREVQILSLLSGHEGIVEFMAAYEDLMNVYIVMELCQGGELMDDILSNQGPYKEATAVELVWQILTAVAYMHEKNVIHRDIKPENFIFANEKDNIIKAIDFGLSYKCQENETVKEVVGSPFFVAPEVLKQAYNLKADEWSVGVLTYILLIGTRPFFGRTDSEIFKAVLRDEPDIDNADLSLPAKDFLKRLLNRNVESRATAREALDHPWLRDRSAMPVQPGCGSSDTRSGLDSTRHICNDRTESLQA
The following text describes a protein:
Function:
Seems to mediate cell cycle arrest before mitosis in response to DNA damage. Is probably also involved in the transition from mitosis to endoreduplication.
Subcellular Localization:
Nucleus.
Sequence:
MGDETVDGIEAKYISGLSTIMVATIQEAKDRISQIEYIFCSQLFPNFQSKSKAFEKVYSEARLAACDTWKDREKSLLDQIEELKVENQQIKSDKEKLAEELGKTASMPLRLTSLQGYIDHLKKKMKSRSKMVGDARDLYYRLVELLQVKGLDELSEDGINMIVSEVKSLKMKTEFLQEELSKKTLVTENLLKKLEYLSTEAADGERKLSSVEEEKQRLKTRLQVFEENVGRLEEILRQKTDEVEEGKTALEVLQGKLKLTEREMLNCKQKIADHEKEKTVVMGKAKDDMQGRHGSYLADLEALRCQSEEKSFELAMEIKKNKELSRTCKKWKSQHTFLCKRFNFTPDSVLHQSSLEDENKEIGQHEKSAISSYLERKHSETAEGADKVRIGTGSSGNNYEKESIIKTVQTPITSISPIVRSPGAAKPPQLSGLKRPASIWRDTRSRQSPGGHDPHDDFLDTPIENVKRVAGEEKHVHDVAKKDDSDDETQDMNPKPSPSRQRIQIAETSKKSFKHVESVRKKAERENLKGIECKQCKKFYDAVHPENEGNGNKSLRCEHHEGVSRHRYRYAPPMTPEGFWNIGFESEM
The following text describes a protein:
Function:
Required for pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MVEPHLFCGPEFTLEVPSELPLPVEPNILLQLQSELYNLLTPLVRHKLHATWGTGTGSCDGTVPPPPCELCFVEVVESSPVPDPGARENEKDNVSNEKNEATAKLVLRIKDSRAASELFVIGLRNPFITLPHGIRLHNRCGGSAVGTAKARATPVEILRKKELLRSRMNFDEDLWELLQGSLTSEWLLALEETYKQHKQQQSSNHEAVTSLRESQRHERRVESLLHYCEQNVLYIGVMDEEGKATPFLLAIGAFYKLGLTRHDALVHFARHHRRTIRALALFIARYTTAPEELEPFFTPSLTDEVVVACAEDQQVTCSMRQLAEDLLLHDEVCEAWPPTLHPFWIEHTVRPMMLRVEADRKRREELFQERESGVATEKEQGNRTGSGSSAPGGSGKGVGVFGFCNIMELHAYVREKQRVLVPQRVLSMLSKPRGGDSGDRDYADDGDDDDDDFLIKVRVEGDGDAEQNALHHQNKRGIDTKQPKQGQQQLSVRQGDSRKRRRQGTTTARSLAVTGAYRTILTLLGRTEPFDPHCEHFLQF
The following text describes a protein:
Function:
Required for synthesis of pyridoxal-5-phosphate from vitamin B6 (By similarity). Important for bud site selection.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPRLLATQSHVVHGYVGNKAATFPLQCLGWDVDCCNSVQFSNHTGYGLDKVFGTITRETDLKELLSGLFDNFSQDYQALLSGYLPNKNSVRCMGTYYAKFKEANPEMIWLMDPVMGDEGQLYVSEDVIPEYRKLALSPKQLVDIITPNQFELEILYGGEIKTKEHLKKALKKLHQTIPVIIVTSCDCKMFDDKDFIYCVASMEGKTPIVYRVPFIDSYFTGVGDLFSALLLDRVYKILSNPTTTLKFEDQVNNVLNVIQKVLKITRSYASGKMKAKMGSALEMKEMELRLIESRDIYETINIHQTDYIYARL
The following text describes a protein:
Function:
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
Sequence:
MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVLRV
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Sequence:
MADNTESPPPVGNDPPVARRQRAPTITIDTTAVSPQPQESPESAPRGVSYSPTSLGEDAYSPTAMDPIASHWTPSHQHSNSLGQRSEMRQSTSFDSRDSRPTSPHNVSSPVTYRPMDPQNFLSVPGAAGRSRQNSVNSNDETRSIASSQGETVIGGSSHQGDKIGRPLSSNTSDNAQIMNDPDALKPDQGREADFEVVDNPFAYTPGQLNKMFNPKSLSAFWKLGGLAGLEKGLRTDRKAGLSMDEVEVDGRVTFDEATARPSGNPPAQPKAATETVLAKTDSHAAADHHKKHHGDDHYTSRKRVFSDNRLPEKKGKSLLELMWITYNDKVLILLSIAAVVSLAIGLYQTFGQAHKPGEAKVEWVEGVAIIVAIVIVVMVGSLNDYQKERQFAKLNKKKQDRLVKAIRSGKTVEISVFDVLVGDVLHLEPGDMIPVDGILIEGYNVKCDESQATGESDIIRKRPADEVYAAIENNENVKKMDPFIQSGARVMEGMGTYLVTSTGIYSSYGRTLMALDEDPEMTPLQSKLNVIAEYIAKLGGAAGLLLFIVLFIIFLVKLPKSQHTPAEKGQQFLNIFIVVVTIIVVAVPEGLPLAVTLALAFATTRMLRDNNLVRHLKACEVMGNATTICSDKTGTLTQNKMQIVAGTVGTTHRFGGVGSAGGLNPETPDSPTEADVTAKEVVASLDASVKELLLKSISLNSTAFEGEIDGVKSFVGSKTETALLEFAKEHLAMGPIAEERANAKILHLIPFDSGRKCMGVVVALDNGKARLYVKGASEIMLEKCTQILRDPSNGITAGPLTQENRETVLKLIETYARNSLRTIGIIYRDFAHWPPAKARRTGEDKEEIVFEDICSQMTFVGMVGIKDPLRPGVPEAVQLCQKAGVVVRMVTGDNKITAEAIAKDCGILQPNSLVMEGPEFRNLSKAKQEEIIPRLHVLARSSPEDKRILVKRLKDMGEIVAVTGDGTNDAPALKMADVGFSMGIAGTEVAKEASAIILMDDNFNSIVKALKWGRAVNDAVKRFLQFQLTVNVTAVILTFISAVSNKEQDSVLTAVQLLWVNLIMDTLAALALATDPPADSVLDRKPERRGSGIISTTMWKMIIGQAIYQLAITLLIYFGKQGVLPNYDDNVTDDQIQTLVFNTFVWMQIFNQWNNRRLDNNFNIFEGLTKNLFFLGISAIMMGGQVLIVFVGGQAFSIAKEKQTGAMWAYALILGFISIPVGMIIRLIPDSLFERMVPEYIKRRANKTPDLTVSDDERFEYYPPAFAEVRDELAFLKQFKGGRINNLKFAMKHPRETFMPKRSASHSRSNSKSNSINVPMTPIRKDSTGGAPSIAPPTPDSRRRSRSTRSRSNSALGASMVMTGIIAGSVAAGWAPSPVERRPDSDFGLFPPKSSPHAESSQSEVQPSQRSLTPSINEEQETPDIVPSIVEQTVPILSVPKPPGQKSA
The following text describes a protein:
Function:
Involved in the biogenesis of rRNA. Required for the formation of 18S and 5.8S rRNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MGTGSVNKRKLNNEQRPEEAAGRQMASKSVLASGGDVAFPRGGASALTPLELKQVANEAASDVLFGRDDGKPAEERPRKKKKTSKASKEDAVAGKEDRTDIVEHLSFKGLTSGTVLLGQLCGVNRTDLCIALTDGLRGYVPLTNISAPFTSLLEQLDQSMDSGSEDEDDDSDDEQRDKPHTITELPELSKYFTLGQWLRCVVVKNSALDSQKKKNSRIELSIEPSKVNLFETEDLAKHTTVQCAVKSIEDHGALLDLGVQDVTGFISNKDLSKMGDVMPGSVFLANITKRGDRTATVNFEFTAKNSKVSQISSVDAVIPGHTIDFLCEKITNHGIIGKAFGVLDGFLSESQARVFSVTDMKHKYAIGSNIKVRIIATLRTKQGNKVILVSALPHILSLERNLLETEAMHAFPVGYVFDNCKLLGRDSQYLYVSLSDERIGQIHISKAGDAITQEAVKARVTGYNTVDGYYQLTSDPKLLAKPYLRSADIPVGTILSGCEITAVSGNGIELSLFDGQFKAFVAPLHISDIRLVYPERKFKIGSKVKGRVLHVDNKGRVYVTLKKSLVSANDSDIPLVSDFEQIAKLAEEDGKTLATVESFKPSGCVVTFLGNLKAFLPNKEISEAFVQRAQDHLRLGQTVVVKVLEHVAKQSKVIVTRKVSSEDSEKQKAAINDLVVGRSIVDVTVVEKTKDSVVVELNDVGLRGVIYVGHLSDSKLEQNRALLKKLRIGSSLQGVVMDKDVKTRVFNMSCKKSLIKDASKDILPLTFVDIKDKDPNTPMHGYVKSISDRGIFVAFTGKFVGLVLPSYATESRDVDIFKKFYINQSVTVYLLRTDEENERFLLTMSPPQTSNKKEDSNHDVAAVNPVDASVKIISQYSVGTVTKARVKSVKKTQLNVVLADNLHGRVDASEIYDTFEEIENPKEPLAKFKSGDVIDVKVIGFHDSKTHKFLPISHRTGVNTVLELSAKKSALKGAYQPIEFSGMKNGDELIGFVNNFAKGFIWLTLSPALKAKIPDFELSDDGSVFTGNLDESFPLGCALKVKVKELDPAHKIVSVSARKHAITDIKDIKVADKLPARIVKVADSYLLLDLGNRLTGVAFVTDALNEFSLSLRSVYEDKIGSMILASVVGVDVENKKINLSLRTEDATDRYILSHKDLKQGDVVRGFIKSVTDKGIFVYLSRTLQAFVPVSKLTDAYIKEWKKFYKTMQPITGKVVNCESDSRILLTMKESEVNGELKILKSYADLKSGDIFDGSVKNVTDFGVFVKLHNTLNVTGLAHKSEISDSKIDDLSLLFGEGDKVKAIILKTNPEKNQVSLGLKASYFQKAHDDEDEAEPAESIEEANGEEINGEASDEDEAMEDIEYEHTPADAPSHETSSKAHKEAVPTGLSLSAGFDWTASILDQNREDNEESSEDEDFTSKKAKKNKKRHAAVIDRTVDINTKAPESVGDFERLIMGNPNSSVIWMNYMAFQLQLSEVEKARELAERALKTISFREEHEKLNIWIAMLNLENTFGTDETLEDVFRRACQYMDAYTIHMKLISIYAMSSKDDKAVELYKAAAKKFGSENVSLWVSWGEFLLTHEQPDEARAVLAQALKSLPRRSHIDVVRKFAQLEFAKGDPEQGRALFEGLLADAPKRIDIWNVYLDQEIKSSNRARADALFERVLVAKLSRKQAKFFFNKWLQLAESTDDQRGVEYIKARAADYVRKHDSVPDAE
The following text describes a protein:
Function:
ABC transporter that may affect phytic acid transport and compartmentalization. May function directly or indirectly in removing phytic acid from the cytosol or in vesicle trafficking. Required for phytic acid accumulation in developing seeds. Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MGGTPWWLATTDCSPPPSSGSSETLAFLFLSPCPQRALLGALDLLFLLASLFLLLLRRPLGHSADADDDAPEHESLLRPAPPTKPQDTVRYGGAVALGASAVFAAGSAVLLALAVFLPLRSPEQGAPPLPWRVMESAFLATHCAAHAVAAWTVAAAAHPRLVHLRVFWVATALALALFSASASIRFADGSPLFPDDPLAFAGLLVSLPLVYLAITGSSEPRSSVGEEDEPEPAEDPGAATPYVGASFLSRATFSWVNPLVSKGHAEGSLAADDVPPRVISPVGVALWLSFWPQFVLIAALGLVQLATMYVGPSLINKFVDFIRRGGDANAWGEGLWLVGILLVGKATETLATHHYNFQGQLLGMRIRGALLTAMYRKSLRLSPGARRAHGAGAVVNYMQVDAGIVSNAMHGLHGLWLMPLQITVALLLLYSHLGSAVLMTLAVIAAVTVVTAFAGKLSLAYQLEFVGARDSRVKAITEMLNNMRVIKLQAWEDTFGSKVRQLRQAEVGWLKRVIVFVCGSTVLFSSGPVAMTVLVFGTYLAAGGELDAGKVFTATAFFSMLDGPMRSFPQTIAMSLQAFVSLRRLDKFLSDAEIDGAAVDCRLDSGGAGDVAVAVKVEGGVFAWDVQDNADGPGEEPVLKGIEMEVRKGELVAVVGTVGSGKSSLLSCIMGETHKVSGKVSVRGSTACVTQTAWIQNETIQENILFGQAMHPEKYQEVVHACCLGKDLEMMEFGDQTEIGERGINLSGGQKQRIQLARAVYQDCDIYLLDDIFSAVDAHTGSSIFKECVRGILKNKTILLVTHQVDFLRNVDTVFVMKNGEIIQSGKYGELLDSCSDFLALVAAHDSSMEAPGVHGCHVQNTENSQDTMVLPKTPSVNSKSSNENSVAPSKEAGSSKIVQEEEKESGRVSWQVYKLYITQAWGWWGVVLILAISVLSEASRMASNYWLSYETSGGTIFDISMFLGVYVSIVAVSVVFQFITILFIAFLGLKSAQAFFGKMFSSILRAPMSFFDTTPSGRILSRASSDQSKIDTALLFYFGAGISMCISVVSSIAVTCQVAWPSVIAVLPLLLLNIWYRNRYIATSRELTRLQGVTRAPVIDHFTETFLGSPTIRCFGKEDEFYQTNLDRINSNLRMSFHNYAANEWFGFRLELIGTLVLSITAFLMISLPSNFIKKEFVGMSLSYGLSLNSLVYYAISISCMLENDMVAVERVNQYSTLPSEAAWTVSDCLSLPNWLCRGDIDITDLEVRYRPNTPLILKGITISISSGEKIGVVGRTGSGKSTLIQALFRLVEPAKGQIIIDGVDICTLGLHDLRSRFGVIPQEPALFEGTLRTNIDPIGQYSEAEIWQALERCQLKDTVAAKPEKLDALVADMGENWSVGQRQLLCFGRVILKCSRILFMDEATASVDSQTDAAIQRIIREEFLARTVISIAHRVPTVMDSDRVLVLDAGLVVEFDAPSKLMGRPSAFVAMAQEYASRS
The following text describes a protein:
Function:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Sequence:
MASESEKTKIVTTFLKDSPPGEFNNVLKDCREVVGDDSIFQECLPICLHDYNTEQLTVVMDGTNPVIISKYTEQSAQEFIDPVNKKVVTFDHLSKQITSSQPLSSGLPGNDSLRQALQKKLDNYAKEFYPKGAAIVMPKDNNTYTIIISAADLKVAQFSNGKWRSEWTISVGSKVTCEGRIRVQVHYFEDANIQMHTDTKKKVTCNGGSEDQIAQNVIKEIKNIEDTFHAELDKIFATLSDNCLKALRRQLPISRQKINWANWKGHKMMK