lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4).
Subcellular Localization:
Secreted.
Sequence:
MESGGPGNYSAAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLSGTATLELRCLLPEGASELRLDSHSCLEVTAATLRRGQPGDQQAPAEPVPFHTQPFSHYGQALCVAFRQPCGAADRFELELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALIEVPDGFTAVMSADTWEKRGPNKFFFQMSHPIPSYLIALAIGDLASAEVGPRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMNVTGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQDQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAELWVTSEPDMQAIEAVAISTWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDYQEEFQKVKDFLQSQGKQKYTLPLYHAMMGGSEMARTLAKDTFAATASQLHSNVVNYVQQILAPKDS
The following text describes a protein:
Function:
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.
Subcellular Localization:
Secreted.
Sequence:
TWPTSQGDVYYTEPYTVAAGETFDGGLKTYQRSDITCEGQEESGSSTAVFLVEAGGTLKNAIIGTDQMEGVHCDKHDCIIENVWWDDVCEDALSVKGGSASSVTKVTGGGARNADDKVIQHNGYGTVKIDGFYAETFGKLYRSCGTCGDKQRFVSVSNVYAVNPSVSIVTVNDNYGDEATLSNIYISSDDDGYTVCAWSQGSEDGEPTELGDGIKDPLCQYSESDI
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MRSSLKPVLSNLRFNSTIASESLRFHVSRTPSKNLPVYLDYKQRGTKILTLIRKIHGDSNALRLRLISTLKMSPKDVYVNKLTNQVVLKGNHIVTVREWLQDQGF
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
Subcellular Localization:
Nucleus.
Domain:
The hydrophobic-rich region (HR-A/B) corresponds to the oligomerization domain.
Sequence:
MEDDNSNNNNNNNVIAPFIVKTYQMVNDPSTDWLITWGPAHNSFIVVDPLDFSQRILPAYFKHNNFSSFVRQLNTYGFRKVDPDRWEFANEHFLRGQKHLLNNIARRKHARGMYGQDLEDGEIVREIERLKEEQRELEAEIQRMNRRIEATEKRPEQMMAFLYKVVEDPDLLPRMMLEKERTKQQQQVSDKKKRRVTMSTVKSEEEEVEEDEGRVFRVMSSSTPSPSSTENLYRNHSPDGWIVPMTQGQFGSYETGLVAKSMLSNSTSSTSSSLTSTFSLPESVNGGGGGGCGSIQGERRYKETATFGGVVESNPPTTPPYPFSLFRGGF
The following text describes a protein:
Function:
Subunit epsilon, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). May be essential for the assembly of F(1) and may play an important role in the incorporation of the hydrophobic subunit c into the F(1)-c oligomer rotor of the mitochondrial ATP synthase complex (By similarity).
Subcellular Localization:
Mitochondrion. Mitochondrion inner membrane.
Sequence:
MVAYWRQAGLSYIRFSQICAKAVRDALKTEFKANAEKTSGTSIKTVKIKKE
The following text describes a protein:
Function:
Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit Polr2A/Rbp1 and Spt5, and (2) degrading the exiting nascent RNA transcript via endonuclease activity. The integrator complex is also involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5.
Subcellular Localization:
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Colocalizes with dynein-dynactin on the nuclear surface at the meiotic G2/prophase transition in primary spermatocytes. Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M.
Sequence:
MFERNQKTIFVLDHTRYFSIASEEYISMEYLKGKQTGLEAGANGGTQFSKSLWTCACESSIEYCRVVWDLFPGTKHVRFIVSDTAAHIVNTWSPSTQNMSHVMNAMVMVGVPSMPQSSDSSVIHGLRAAIEALAEPTDEQMQAMGGKQTLHIPNEGRVICITSARDNTSMKSLEDIFHTVLVQQNSLMTSPPSKKGLPIDHCHLVILNIVPLGVESLVTNRSLLEISPLLNVEIHTVPAPDISYKLTHLILDHYELASTTVTNIPMKEEQNANSSANYDVEILHSRQAHTIAGGPDFNLPTSIKTGSTYETVTLKWCTPRGCSSADLQPCLGQFRVTPVDVTSRPSSCLINFLLNGRSVLLEMPRKTGTKATSHMLSARGGEIFVHALSILRSCMDEAPAIQDGPGGRVTDYRFGELGQLIKLSRMIPLKAKDPSHPTHSTLRRRLPRYFPWTTSSSILFNLQRQINWLPHFLHLLVKEDMDKQDEVRCQQHIHELYKSASRGDMLPFTNSNGGRLKLSKAKDQYRLLYRELEQLIQLNSFTPHHKNLLESLQSLRSAYGDAPTKSESANALLRSYTESPLSPERLEPTSSSSSNSLLKARKRRMSTCGQRSLFDIISSAERSQSNKRLDFSGRLCTLPGQVAKLYPDFGNKDKDSLVIAGGVASTTASAKEESIRG
The following text describes a protein:
Function:
Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.
Sequence:
MSSIGADPLPTTDSTITIQRPSAHTQRYDRQLRLWASSGQSSLEKSRILVIGASALSAQVLKNLVLPGIGSFVLLDDSIVDGADLGVNFFLQPGESEGKYAAEEMCRLLTEMNTSVASEAKLENPASLLQSDPSFYAGFTLVISVNQSRSFDLALSDALWALQSPSPQVPLLRVRSAGMLAEMQISLKELGIIETHPDSVVDLRITRPFPELLDAAQHFDLNTNDTMEHSHIPFPIILIKKLAEWQAAHDGQLPTTKDRDAFVKQVNASRVASNPDAENFDEAISALGKHLWRPIASNGVGGGGVPDEVEAMFQDAACDNLTPASTNFWILVRALREFVAASPSRCLPLSGSVPDMKATSSGYIKLQNIYRTKSLQDLAQFKKLVLDICMAAGVEGKIADDEIEAFVKHAGYLKLIRGRSERQRCQEPNQETAMLAFMDPVNPCTFQHHIALAAADQFLEQNGRYPGVRQQAFPALLVGANGTEKDASGDVQPRAAKRQKSETPTGELDSSITDVKMRDITADQETSKDQDELLTIAKKLATKQFNIADDGDEWEKIENSVGELVRSAHASLPATTALMGGVVAQEAIKLITKQYVPADNTVIYDGIQQAIGVFRL
The following text describes a protein:
Function:
Component of the pheromone signal transduction pathway. It mediates pheromone signals acting between STE20 and STE11. It is absolutely required for pheromone-induced transcription of FUS1. May play a role in cell-cycle arrest in response to pheromone.
Miscellaneous:
MISCELLANEOUS: Present with 1900 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MMETPTDNIVSPFHNFGSSTQYSGTLSRTPNQIIELEKPSTLSPLSRGKKWTEKLARFQRSSAKKKRFSPSPISSSTFSFSPKSRVTSSNSSGNEDGNLMNTPSTVSTDYLPQHPHRTSSLPRPNSNLFHASNSNLSRANEPPRAENLSDNIPPKVAPFGYPIQRTSIKKSFLNASCTLCDEPISNRRKGEKIIELACGHLSHQECLIISFGTTSKADVRALFPFCTKCKKDTNKAVQCIPENDELKDILISDFLIHKIPDSELSITPQSRFPPYSPLLPPFGLSYTPVERQTIYSQAPSLNPNLILAAPPKERNQIPQKKSNYTFLHSPLGHRRIPSGANSILADTSVALSANDSISAVSNSVRAKDDETKTTLPLLRSYFIQILLNNFQEELQDWRIDGDYGLLRLVDKLMISKDGQRYIQCWCFLFEDAFVIAEVDNDVDVLEIRLKNLEVFTPIANLRMTTLEASVLKCTLNKQHCADLSDLYIVQNINSDESTTVQKWISGILNQDFVFNEDNITSTLPILPIIKNFSKDVGNGRHETSTFLGLINPNKVVEVGNVHDNDTVIIRRGFTLNSGECSRQSTVDSIQSVLTTISSILSLKREKPDNLAIILQIDFTKLKEEDSLIVVYNSLKALTIKFARLQFCFVDRNNYVLDYGSVLHKIDSLDSISNLKSKSSSTQFSPIWLKNTLYPENIHEHLGIVAVSNSNMEAKKSILFQDYRCFTSFGRRRPNELKIKVGYLNVDYSDKIDELVEASSWTFVLETLCYSFGLSFDEHDDDDEEDNDDSTDNELDNSSGSLSDAESTTTIHIDSPFDNENATANMVNDRNLLTEGEHSNIENLETVASSVQPALIPNIRFSLHSEEEGTNENENENDMPVLLLSDMDKGIDGITRRSSFSSLIESGNNNCPLHMDYI
The following text describes a protein:
Function:
Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
Sequence:
MRYSPLLTDLYQLTMLAGYLDEGMAETPAVFDLFFRHNPFQGGYAVFAGLDTALDFLEHLEFSEDEIEYLQGLGLFRPAFIDFLRSFRFRGRVTAPPEGTVVFANEPLVTVDAPLAQAQLVETALLNIINFQTLVATKAARIVHAAADGTVLEFGLRRAQGPDGGLSEARAAYVGGVRSTSNVLAGKTFGIPVRGTHAHSWIMAFSDELTAFRKYAEVFPDSCILLVDTYDTLRSGLPNAITVARELRAKGHELVGVRIDSGDLAYLSRQARRLFDEAGFPNVRIVASNELDEFVIESIRAEGGCVDIYGVGTRLATCAGEGGGALGGVYKLVRIGDRPRLKVTSDLAKATLPDRKRLLRAVAADGTFIQDVICLDGEEVLPGHTVFDPANPLQHVTIPMKARLEDVRSVAMENGRRTASRSVSLDRMADRSRNQLALLPQGCLRFINPHRYKVSISQGLNDLRLRLMEEVRHGYHDIANP
The following text describes a protein:
Function:
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
Sequence:
MTSSNELTFPKQRRQHGFYRIAAVSPKVVVADPAANAAETIQAMDAVVQQSDPDLILFPELGLSAYTCGDLFATQTLLDASLDALRTIVTHSHSCDAAIIVGLPLRVGTSVMNVAALVRGGVIRGLVPKTFLPNYREFYEARHFRAASATDPATVRIDRQDIPFGTDLLFQDGAATLGVEICEDLWVPVPPSSHAAIAGANVVVNLSASNELIGKAQWRRDLVVSQSGRLIAAYAYSSAGGGESTSDLVFGGHCLIAENGALIGESRRIGDTDDEDLPVQTQLIRDVDLQRLDHDRRVVGSFDDFQASLPRPYRTIDVAWAGSKKQSSSTTLLRTGKGNEKDATHSDQSDFNRLLRRVDPHPFVPDDLSKREERCGEILAIQTAGLVKRLQQLPADLPLTIGISGGLDSTLALLVAVSAVDQLKRDRKVIDAIIMPGFGTTQHTNDSATQLVEGLGVTSESIDIRPLALRTFLDIGHSPLGLAIDVSTKIDDLQSRLQKVDVNATDLKFENVQARLRTMLLMSRGFVLGTGDLSEQALGWSTYNGDHMSMYNVNASVPKTLVRYLVQYAADHRYRSSLHETLHRIADTPISPELLPPTEDGEIRQNTEASIGPYELHDFFLYHFVRGGCDVAKMCFMAEQTKFDLPHSAELIEATAKTFVRRFFQNQFKRNCVPDGPKIGSVSLSPRGDWRMPADASSAAFRD
The following text describes a protein:
Function:
Proton-coupled transporter that transports a wide spectrum of oxo derivatives of heterocyclic nitrogen compounds, including allantoin, uric acid and xanthine, but not adenine. Mediates transport of uracil and 5-fluorouracil (a toxic uracil analog); Proton-coupled transporter that transports a wide spectrum of oxo derivatives of heterocyclic nitrogen compounds, including allantoin, xanthine and uracil.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MMIAQELGIYVVESKGGAILCLLLSLLCLGTWPALMALLERRGRLPQHTYLDYSITNFLAAIFIAFVFGGIGESTHEAPSFITQLTQIQDNWPSVLFAMAGGVGLSIGNLATQYSLAFVGLSVTEVTAASITVVVGTTVNYFLDNGLNRADILFSGVGCFMVAVCLGSAVHSSNSADIKAKLGKLSGDCETVTPEECQRLFGVEEEEEEEKEMENVKEGSAAFLIALENKRAIKVLGKSMVVGLGITFFAGLSFSLFSPLFNLATNDQWHTLKQGVPKLIVYTAFFYFSLSCFVIAVALNISFLYKPVLDSPRSSFREYLSDWNGRGWALAAGLLCGFGNGLQFMGGQAAGYAASDAVQALPLVSTFWGIYLFGEYRRSSTRTYALLVGMLVMFTVAVGLLMASAGERETRFT
The following text describes a protein:
Function:
Catalyzes the oxidative deamination of D-amino acids. Has broad substrate specificity; is mostly active on D-proline, and to a lesser extent, on several other D-amino acids such as D-alanine, D-phenylalanine and D-serine. Mediates electron transport from D-proline to coenzyme Q1 in vitro, and is involved in the electron transport chain from D-proline to the c-type cytochrome in vivo.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MKKEVVVIGGGIVGLSCAYSMHKLGHKVCVIEKNDGANGTSFGNAGLISAFKKAPLSCPGVVLDTLKLMLKNQAPLKFHFGLNLKLYQWILKFVKSANAKSTHRTMALFERYGWLSIDMYHQMLKDGMDFWYKEDGLLMIYTLEESFEKKLKTCDNSGAYKILSAKETKEYMPVVNDNICGSVLLTENAHVDPGEVMHSLQEYLQNVGVEFLYNEEVIDFEFKNNLIEGVITHKEKIQAETIILATGANPTLIKKTKNDFLMMGAKGYSITFKMPEELKPKTSSLFADIFMAMTPRRDTVRITSKLELNTNNALIDKEQIANMKKNLAAFTQPFEMKDAIEWCGFRPLTPNDIPYLGYDKRYKNLIHATGLGWLGITFGPAIGKIIANLSQDGANEKNADIMLFSAFFRD
The following text describes a protein:
Function:
May be involved in vesicle transport between the ER and the Golgi complex.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSVILFASVVRVRDGLPLSASTDHEQNMSVQETKKYLKVVSKKLEQLPDRCTLKRGPHNVHSISSLGVGYMMLCSENYPIVLAFCFLDELQKEFITTYVMSQINTAIRPYSFIEFDNFIQKTKQRFNNPRSLSTKMNLADMQTEIRLRPPYQVSLQEAGLANGLNHRKHLEYKGIASQQRLEPLTLTGIISLLLTLLCAGLNLIRGFHAIESLLQNDNDFSCVIAFFLGTAACIYQCYLFAYSTSWRNVKSFLAFGLICLCNMYLHELRTLWQLFFHVTVGAFITLQIRLRQPQSKSPDYNV
The following text describes a protein:
Function:
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MSNPKAEGLIAEGQKALKKFFGSKKDKAYDASDKFCHAARLYKIDRNFEKAGECFLMAADALHNVGDDNSASSHYIDSTLMFFKVQAMTAKAHEALDKAVDILCTLDSPAKSAQLIVKSCELLEKEQAYDLAIQAYNKALGLLTDMPDVSALQASIHEKKAYLFCEKRNYNEAAKSFTEAATLRNQIPLTQTSAQSTFVVAELCRLAAGDLQGAIKEYDNIVYQCPSIKVNFEGRYFNAIMDAAQNTPEKLPEAIKAYKDTHENAKWMVDILNLIQNPDEREML
The following text describes a protein:
Function:
Binds fatty acids and retinol. Is specialized for the preattachment embryo. May be important to maintain the pregnancy and may transport small hydrophobic ligands from mother to the developing embryo.
Subcellular Localization:
Secreted.
Sequence:
MNLLLLAMGLILPRRPHALHMGPGDPNFDEKLVKGKWFSVALASNEPKFIAKDTDMKFFIHKIQVTPESLQFHFHRKVRGMCVPTMMTAHKTKKKFQYTVNHSGHKTIFLEKVDPKHFVIFCAHSMKHGKETVVVTLFSRTPTVSPDVMWMFKKYCKTHGIHTSNIVDLTQTDRCLHARH
The following text describes a protein:
Function:
Commits homoserine to the threonine biosynthesis pathway by catalyzing its O-phosphorylation.
Sequence:
MSDEAAKPLPEKVSLRVPATTANIGPAYDTLGMALSIFMELTVELAEAFSMTVTGEGQEHISTGEDNMVVQTCRIAFEEYAHKSMPPLKFTMHNNIPYKCGCGSSSAAAVAGFVAGMMLSGLTLETHNSESLLSAISKIEGHSDNAAPAIYGGIQLVYKKDDGRTMTYHVPTPPNLSIVLFVPHKLMKASTHVTRELVPTAVSLRDAVHNISGTAILTLALSTGDLRMLKDASDCLHEQQRSRKLYPHYSACAKAAREAGAEYAFLSGAGPSVCAMVSGRHGDLLTQPMEERKAEMVAEAMVKAAEAVGVQGRVIITMPSDVGVHLSGTTCIRPNIQYTSI
The following text describes a protein:
Function:
Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.
Sequence:
MSSESSTEGDSDLYDPLAEELHNVQLVKHVTRENIDALNAKFANLQEPPAMYLIEYQELTSKLHELEAKEQELMERLNSQDQQEDSSLVERFKEQPHYQNQTQILQQQRQLARVHHGNDLTDSLGSQPGSQCGTLTRQPKILLRAHLPNQQRTSVEVISGVRLCDALMKALKLRQLTPDMCEVSTTHSGRHIIPWHTDIGTLHVEEIFVRLLDKFPIRTHIKHQIIRKTFFSLVFCEGCRRLLFTGFYCSQCNFRFHQRCANRVPMLCQPFPMDSYYQLLLAENPDNGVGFPGRGTAVRFNMSSRSRSRRCSSSGSSSSSKPPSSSSGNHRQGRPPRISQDDRSNSAPNVCINNIRSVTSEVQRSLIMQARPPLPHPCTDHSNSTQASPTSTLKHNRPRARSADESNKNLLLRDAKSSEENWNILAEEILIGPRIGSGSFGTVYRAHWHGPVAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHCNILLFMGCVSKPSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTLPKIHRSASEPNLTQSQLQNDEFLYLPSPKTPVNFNNFQFFGSAGNI
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MLNPNKPSNELKELTRAHTESFNYFLEKGKEDILKYMKKYKIIKKDSTELMELSCTGISIEKPTYNGLPLFPYMCRSAALTYSGRIKLTITIKENDSNKTIEVDGGEIPIMVGSSKCWIGSEYTTPEERINIREDPHEIGGYFIINGIERYLRMIVYAKPNHPLAVTRPSWTNKGAHFTKYGIIIRCMRDDITTLTNTLHFLDNGKVSLRFIFKKQEFFIPVVLLLRVYGGMSDREIFQLITMNNYENSNLVNAAEMLVRRENGSPLNGLNSPEQVLTYIGSKFRLIMDGTEGVNDTELGKRVLDEFCLVHLSSYAEKSDLLIFMLQKLFALVHGEIDEEGVDTPMSQGVLLPGHLYQTVIKEEIQNVLSKARLFILKDLKDVKKGSKVTEKIYLQRALSSAAKSFGTRIKSFISTGNFETNTTTDLQQTNGFSITAERLNHSRFTSHFVSVHRGAFYTTMKTTSIRKLVPEAWGFMCPVHTPDGAPCGLLNHFAVSCRINARKHPLPDQQIIDLCTELGMVSTQFMKLPSIYIPVLLNGKVIGKVSPHEINSFVQQLRYERAVYNPKIPNTLEIGYCDGYLQDGYHALYLNDLPGQMIRPVIHRATGNIVNIGPYEQVFLDIKCGDSIEGMNNAEYEEISALNSLSLLATLTPFCHMNQSPRNMYQCQMAKQTMGIPALSNKYRSDTKLLWLHYPQRSICQCALMEPFGFNEYPTGANAVVAVISYTGYDMEDALIIKKSAIERGFGHGSQYKAYKVDFEKEGEKNEMFSGTTSSGEVFDEHLDDDGLPRPGEVFENSPIYSHIDKITGKIKGKVLMGERGYIESVRIVGGDNIDSGLQKAVVRVRYNRTPVIGDKFSSRHGQKGTLSVHYQEKDMPFTESGMTPDIIINPHAFPSRMTIAMLVESMASKVGALKGEYQDATPFKFDEENSAVDYFGKQLLKYGYNYYGSEPLYSGIYGNELQSDIYIGIVYYQRLVHQVKDKYQVRSTGPISIVTHQPIKGRKRGGGIRFGEMERDSLVAHGTAMLVHDRLFECSDKCYHYVCTKCGSICTIKRSKEYDKMVCQSCGPTSIVKKIQIPYVFRYLAAELSAMNVRLNLRVDRNSY
The following text describes a protein:
Function:
Probable transcription factor involved in the regulation of floral organ abscission. Participates in processes that directly or indirectly influence shedding of floral organs.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing ZFP2 fail in the abscission of floral organs (sepals, petals and stamens) after anthesis.
Subcellular Localization:
Nucleus.
Sequence:
MDYQPNTSLRLSLPSYKNHQLNLELVLEPSSMSSSSSSSTNSSSCLEQPRVFSCNYCQRKFYSSQALGGHQNAHKLERTLAKKSRELFRSSNTVDSDQPYPFSGRFELYGRGYQGFLESGGSRDFSARRVPESGLDQDQEKSHLDLSLRL
The following text describes a protein:
Function:
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
Sequence:
MNIIEIIELKKNKKKLSQDQINFCISGLVNKSIPDYQISALLMAIWFNGLDDNELYFLTKAMIDSGKIYKFHPEYKKILIDKHSTGGIGDKVSIALRPILVSFDLGVAKLSGRGLGFTGGTIDKLESINVNTDIDLKNSKKILNIANMFIVGQTNDIVPADKLLYALRDVTGTVDSLPLIAASILSKKFALESDYIFIDIKYGQGAFCHDIETAKKISNIMKNLAKKFKRKVYFVLSDMNEVLGNTVGNAIEVKEAIDFLKNNSDVGTYFKKLMFDLVTLILLKTKKCKTKKEAKEKINYVLENKIAFNNFCNWIELQNGNIAKIKNDTFFKPKYWTNIAAWKSGKISYKSIIELAEIGVDLGSGRRKKEDKIDFQAGIYLHAKSNEKIKIKDKILTLYSSKPIKQDLIDKAKKIIKIS
The following text describes a protein:
Function:
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MLRIAVPNKGSLSGPAGEMLHEAGYQQRRESKELRIVDPVNEVEFFYLRPRDIAIYVSSGKLDIGITGRDLLVDSGAHAEEILPLGFARSTFRFAGKPGAATGIDDLKGRTVATSYEGIVAAHLADRGVDASVVHLDGAVETAIELGVAEVIADVVETGTSLRNAGLEVFGEPIMKSEAVVIRRSDAEPDETTEPKVQQFLRRLQGVLVARTYVMMDYDCRVEQLEKAVALTPGLESPTVSPLHNEGWVAVRAMVPAKEAQRIMDDLYEIGARAILTTAIHACRL
The following text describes a protein:
Function:
Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities. Acts as an inhibitor of C-sense gene transcription (By similarity).
Subcellular Localization:
Host nucleus.
Domain:
There are 3 rolling circle replication (RCR) motifs. RCR-2 is probably involved in metal coordination. RCR-3 is required for phosphodiester bond cleavage for initiation of RCR.
Sequence:
MASSSAPRFRVYSKYLFLTYPECTLEPQYALDSLRTLLNKYEPLYIAAVRELHEDGSPHLHVLVQNKLRASITNPNALNLRMDTSPFSIFHPNIQAAKDCNQVRDYITKEVDSDVNTAEWGTFVAVSTPGRKDRDADMKQIIESSSSREEFLSMVCNRFPFEWSIRLKDFEYTARHLFPDPVATYTPEFPTESLICHETIESWKNEHLYSESPGRHKSIYICGPTRTGKTSWARSLGTHNYYNSLVDFTTYDVNAKYNIIDDIPFKFTPNWKCFVGAQRDFTVNPKYGKRKVIRGGIPCIILVNPDEDWLKDMTPEQSDYMYSNTVVHYMYEGETFINYSFASGEDVTASQ
The following text describes a protein:
Function:
Transcription factor involved in imaginal disks development. Isoform rn is required in the wings, antenna, haltere, proboscis and legs disks, while isoform roe is required in the eye disk. Together with nab corepressor, it is involved in the initiation and maintenance of wingless (wg) expression in the wing hinge, by limiting the expression of wg to this compartment. Also required for the epithelial-mesenchymal transition branch of basolateral junctions signaling.
Miscellaneous:
MISCELLANEOUS: [Isoform roe]: Produced by alternative promoter usage.
Subcellular Localization:
Nucleus.
Sequence:
MIMHGTWYKGPQLAHHPHSNPHNSSHGHSDYHQFRSYPSFVVTPYHDGHVQGPATPTPCTAPPTPCNGPVPVSVPVSIPVCHTGGQGSPVIVESSFAIAAAAAAAAAAVAVGGSSATPLLPSPPIKIEQVFGEPSSLGAVVEDYALGLDCPVEHTFRKPHNNNGYSWSTGNNNEVVSHSSNGHTNNHPTTPPTPPNEASATQATSVSAINLNQAQPASQTRSNFGSSIKSPPSEPDAVTAATCKSQENNSGQNPTPNSLSDHNPAHNLNSNSTAAAVAAAAAAAAAANMPIGGVQGQNPTQGLVHWMSAVMAEHMTGQTHHDPGAVGMHYMWNGNVDHAKDISDYNLWPPTPRSHQHASEHHPMSLKQEYEAKMNDHHHNNLQKGHFLDDNRLEHHAVTGQGGLGLGASNGVGGGGGGASVVGNSSLGASSHHAVAAAHHHNQAVAAASAAALLVVPQPINASKMGGPGGVSSVAGGHATGGGSGRKYQCKMCPQIFSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHAERTDKRPPIVPGSAAAIAAAAAAAAGGSANPANGPPPPPNPAQHQRNNLGLPPVSIAPSDNGYWPKVSPDSAAAANAMEVMHQQQQQQQQQQQQQQQQQQQQQQQAHHHHPQHGVPPQQHVPPQQQQQQQQQQQHHHPQQQPPPQHSMEAHYAQPTAPNGSQSNGHGAELQPHHRMPDPVREDIASTPSAVGPYDAASITKTTSNSAFTPINSMPPHLNSLSHHPMAQRPYLYDAISFPNKNVNQNNANAFPNQLISLHQIRNYAHQPAGLMAGEHLLGVSVGPGKDKG
The following text describes a protein:
Function:
Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MGFPAAALLCALCCGLLAPAARAGYSEERCSWRGSGLTQEPGSVGQLALACAEGAVEWLYPAGALRLTLGGPDPRARPGIACLRPVRPFAGAQVFAERAGGALELLLAEGPGPAGGRCVRWGPRERRALFLQATPHQDISRRVAAFRFELREDGRPELPPQAHGLGVDGACRPCSDAELLLAACTSDFVIHGIIHGVTHDVELQESVITVVAARVLRQTPPLFQAGRSGDQGLTSIRTPLRCGVHPGPGTFLFMGWSRFGEARLGCAPRFQEFRRAYEAARAAHLHPCEVALH
The following text describes a protein:
Function:
Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).
Sequence:
MTLGIYLFSRLEIGASLATEMWSFMSFTSRRKVESDSSESSETLSREDAEEDIASSSEDTFEDCSEEPEVCSSADCTAENVGLANLSIYPPLSSIASQAVSMDRECPAGLALSSLGNFSPESYASPAKRIKSYNDARGHSPAGVLTQAAISWASSPDTHSWHGGPNSSVERVEPGFASAPMNQNCQVAERSPFHVTQHGCRSRNTSPQEPPYPRIQDTHGRNLNQCNSKHPSGGLSTNHSSNVGPVRSLKGSLPADRHTFLNGVHRDGIANASSDILLPGARDGNYGSNGPTMQFGISQVRSNSSLSADIHYELRDGTSVSSGVPKRAVKTVAGPIGSASYLFSPGSNLPRKYAPSTGYCVQETINENAAPCVLSSFPRNSSEKSEPVSSTGLLGDDRFVRSMYGMESVSPPEPGKYTQCGRRSVGAGVLHGVKMPWSSLDELIDQSLEEEFRPENHAPQVVLETSGVPTLDAFVKPSFQEPFQKRMDEPILDDRKDLPGSSVEWPQLTEHLHYLGTLDFSTQVFPILTSLRGKPLEKAFTLDELRSIGTQPKEGVCQYLWYMDGLKGWSTPGVPPKRFQPDTSNYTCRIKPTGQILFELVDEKKQAKSLVHRTLGFDKVLKVAFEAEVEDGKRVPLSQDQYSMYCRLAKNGIFVGCRRYQYFAHKASDKFEKKMEGNVKCFFVCTDSRGEVDLRNPYFRRFNSIAEARTLFMHIHQTESIAKFIARMQLILSKTMTIDLDWTKVVVREKMDLQCQDGISTDGTGFISTNLARIIPTSILNGRQKTEPDRNEDYPSLSQVRVLYEGAAYKGTLLASEALPPNTIKLYKSMKKVGRDDEVLLPSVKSLEIVSTSQKPRKLQGVYTAKLSRDLIILLTTCGVPGSFFIDLVKAAIEDNHLIFSDYNVAMNEVLEWETEKTEILLMMINARIPLTEPFLHRSLLDIVKRKLEDFTTGKVNLPESFYLMGTADPTGTLKRNQVAIVLSDGPVYCPKLLVYRAPGKHPGDIHVFEATCNSVLQKVIGSGKYVIYFSTQGPRPIAEEIGKGDLDGDRYWVCKNTQLVSLFKEYPSRWAKLPSTTVPKMLKPADLLPDELEETLFKEYMKARFSSTSLVGKIANLWLKHMDQFLHSDTADKKALHFGAAMKFTPVYYNALDASKAGYTVDFPKGNLPCPRTPHYMNVPGEKMYHSKSIAGQIYDLAKSQELMSSPSYENFELDEAFVVENYEQHYQVWAKHFRSYKPEMSKMVSASHLGKEGTDRPSSDQIYLKYRKILYGGASSYKDCRRLGLKDPHQVLEEASAIYAVVYASAVEKLDREAPRLSFVWNVAGEALCSLYAEKQPGKPSFMSTEGLKEYHRNSKRREASLVKRLFP