lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MSLIVKFENQFHETGVTDVFTEPVDIIPWKFFLLHLFSVQLDSIFDEYLCARINVRDLNLMVIYRSPNSSNDNNDNLIGVLNEFGDLSGRHLVLGYFNFPDIDWKLRVCAGSDYKIENRFLQLIDDRFWLQHVNKPTRYGTNSCPHVLDLIITSEDCVSDLQYSSPLGRKPKKMMSNSQSITNMSQAASSAPPGQTPNQSSSIAINFESPSKKLTPVAMCKYGQELVQEIMHKSYDIFGQLKSIQLVPNERKSRLEDSLHKIEIAFQRLHYVYDSVCNMTKYLEHKPIESYLPMKDKCQDFTTQNIRSDEESKLTEQIQAKNIELKELIDLMRTILWDIDTMMALRKT
The following text describes a protein:
Function:
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
Subcellular Localization:
Cytoplasm.
Domain:
The MATH/TRAF domain binds to receptor cytoplasmic domains.
Sequence:
MDIPIIKLLVEKDSISKKYYCPDCGELLINNFNPEKFKALQCKNGHTKCLQCWEQHLKLRKNCLQCKVPVSSIKDLSLNLYIAQKISANKVYCKNRYYETKNFTIDEENGCKEIIRVDEYEKHIKECPLTYTDCKNYDDFIRANPQIDEKLLKRCGKINKSLLDEHDEQCLYQTITCEHCNELINRIDHEIHLSEWCSDIPIKCEDCKHVFKKKYIQEHKESNCPESVIDCVYVAGGCQKKLKRYNMSKHLVTANHHSQYMSKIIEEQNQDIKELHNFIENHLSKKFIDLDTIVNIQKYLIKNKNQKISQLTEIIKRVDNSFIGLHEFDELEDYISNTIDIISNFDNYKNSNSNNNNNNKNTNENENTNENTNENENIDIVGNSDNENNINENKAENNINSFIKEQIELIKIKSQQFDINSVIEEIRKNYNVEPYQVNGDNAMITSPNKTDVDNLVFDDDEDDFDLEEPQIVGEFIFNKSQETIAIPTLIRQQQQQQQQQQQQQQQQQQQPPPTPLPPQNTTITNDIQMENINENINNNINENNNNNNKNNDDDNITAATATNNSNTTSTHTILNGTNNEASMTDINETTSTTTTAETTEATASESTEESNNTAETTTTTTTTTTTITTAAETVNSTETITLRTSEKVEEKGKDGLETTESFSILNSTENSTISSLKVLSNSMIEPEITTDKENETNIKESIETKIIESIVESSSPTKSLLKQGKEQEQKNQNGNGNENENENENENENENENENENENANANVNEKENEKENSNINTSNDTEPTNDILEDIKKNKENEDSNESEDNKNNNIKSVEDTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNENVYDIKKDRNRENVEDSNDNNSKNENGKINDNGDVKMGSEDKVNDDDDKMAMVDRSNTIFRNQILFKDFTKLNARHGVGVSIKHNHTIGKYKFYSELFINGETENEKDYLSFYLNKCKKENESIIISFGIELLNVDPKKSIRVYWDNELLNNSSQVMYNYGYGETTVIKKSILEDPNNGFLVDNCFIVNLEVYKIIDVPHPPPAHLLQKSSPPAATTTTTTSSSSSKTTPKTKR
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MDKLWSFSSRSGDIVDIGSQQWEEEKDNLHKQLDDLIPLPHVLEDVDCFLNNTKTTNSISREEIPNCVVVLHKSLESMMDKYNRGRRGRRSRFGQDLNDDNLFLDAVDRILKLSTTMSLSGFFLDKTSSVLEKVMIILENDLCAILHHPKSKTFRPTPPPVKSSSFGSLQLQFDLQDERESLRSNNLVDEDDKDGNLLPTFSTEEIFVMNKIATVMINAGYHTECCMTITNFRRNAFKNVMQKLGYTCVRMGDVYKMQWESLEGEILTWNKAFRHCTTVLFNIERKLYNSIFPNQPSISHGMFGDLARAVIINFLNFAQAVVLTKPSSEKLFKFLDMYETLRDDVEPVITLINGDGLEQCAKDLAYEMTMTKHGIIKAVVSMFYDLENSIKGDNERIPVPYGAVHPLTRYVMNYLKYACEYKVTLEQVFYQYCSDDYLATIGHHYVDDSNNNKGTSTSTADIQNEENNDKTRDQNLDGEPNKSPFVVQLMTIMDLLDENTERKSKLYRDMALRCVFLMNNGRYIVQKIKGCVDLHESMGDNWCRRRQTSLKFHHKSYQRETWTKVLQCLNPDGLHQQGNKVSKQVLRERFKCFNSMFEDIHKTQSSWMVSDEQLQSELRVSISALVIPAYRSFMGRFKHHLETGRHIDKYIKYHPDDIETLIDDFFVGNVTSMPRRRT
The following text describes a protein:
Function:
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
Miscellaneous:
MISCELLANEOUS: Present with 2190 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MEKMTVSSNYTIALWATFTAISFAVGYQLGTSNASSTKKSSATLLRSKEMKEGKLHNDTDEEESESEDESDEDEDIESTSLNDIPGEVRMALVIRQDLGMTKGKIAAQCCHAALSCFRHIATNPARASYNPIMTQRWLNAGQAKITLKCPDKFTMDELYAKAISLGVNAAVIHDAGRTQIAAGSATVLGLGPAPKAVLDQITGDLKLY
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing.
Miscellaneous:
MISCELLANEOUS: Present with 2360 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSNIEPQTTAKCILYTTKGNIAIELWAKECPETCKRFLSMLSDGTFTNGEFKELKPTQWLMFNANSTGEYRTVAEEKNPRIRFNRDGLLGWDRRRNTWFITVLADSKHVLNDCNVFGKIVGKSIYIFREILGGEIEASSRDNDVKRFMYPAVLKDVEITIPFFEDIFGSKRRLEDNEKKEQEPAKKLVKSAKVKMVYEDEQEDDDGDVQKLKPRKRMILPAWIKDDSRSEGIKLDASLDQPQEALIREKTELHDNVDEATTKETESQENIKEEPMDKRERETLAMLSKFQERIKNKNILK
The following text describes a protein:
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
APWGSGVTATIYFCVPECSGRNEEERLINYLFLEKKYNKELRPVEQHGDTVDVYLALTLSNLISLKEADETLLTNVWIDHTWIDYRLSWNVSEFDGIDMLRLPSNMVWLPEIVLENNNDAQFEVAYYSNVLVDPSGLCYWLPPAIFRSSCSINVNYFPFDWQNCTLKFTSLTYNAKEIRMLLKEDADEENKWTVEWIIIDPESFTGVCPPMRVCPPALHPLLSIVSITKRCLYILFWVIFEEEPLSKGLVCFRYLMFIMVLVTVVVLNCVVVLNLHFRTPSTHVMTGWTKRFFLERLPRILHMSQPAEPEPQWDGAILPGSSDWVYLKFRVIMTNTSKSTDMFRRQCVFMLCFCVWAAVVKPQEDGGVTDQLYAEIKPALDGANYIIRHRRNKNDYNEVRQGGRLRQQLLLPCSGEKLPIPSESKLVVCLKLRSHRPRQCPFKWSFKMKSLCKHS
The following text describes a protein:
Function:
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
Sequence:
MNINEDSLQKIAELSRLKIRSEEKEATLQDFNKILEYVDQIKGLDVSSIKDDEIYLHHENAIRPDLAGKHLSREEIESFAPSFQNGYFVVPKVIET
The following text describes a protein:
Function:
Involved in amino acid efflux from the vacuole to the cytoplasm. Capable of transporting large neutral amino acids including tyrosine, glutamine, asparagine, isoleucine and leucine.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MNGKEVSSGSGRTQSNNNKKNNNGGSTGISHASGSPLTDGNGGNSNGNSRSRSRSRKSSGTTGGLLKKPPLLVNNEAVHASVPDASHTSCNNGTLEVSINNPEPHVVDAVARHLIRNPSNSLQLQGGDITRDLYKWTNDHPSSPSQYQYPSQPALSTSIPSQAPSFSNRKRSMSFSAASIASSSHLNNNSEANGNPLAAIGLAPAPMTHEEIRAPGGFRRSFIIQKRRKHNVDAPIPNFFTRNFIEFLTLYGHFAGEDLSEEEEEEEETEEEPEEEALETESTQLVSREHGRHPHKSSTVKAVLLLLKSFVGTGVLFLPKAFHNGGWGFSALCLLSCALISYGCFVSLITTKDKVGVDGYGDMGRILYGPKMKFAILSSIALSQIGFSAAYTVFTATNLQVFSENFFHLKPGSISLATYIFAQVLIFVPLSLTRNIAKLSGTALIADLFILLGLVYVYVYSIYYIAVNGVASDTMLMFNKADWSLFIGTAIFTFEGIGLLIPIQESMKHPKHFRPSLSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLNFPQDTSYTLTVQLLYALAILLSTPLQLFPAIRILENWTFPSNASGKYNPKVKWLKNYFRCAIVVLTSILAWVGANDLDKFVSLVGSFACIPLIYIYPPLLHYKASILSGTSRARLLLDLIVIVFGVAVMAYTSWQTIKMWSQ
The following text describes a protein:
Function:
Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1) (By similarity).
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MLSESSSFLKGVMLGSIFCALITMLGHIRIGNRMHHHEHHHLQAPNKDDISKISEAERMELSKSFRVYCIVLVKPKDVSLWAAVKETWTKHCDKAEFFSSENVKVFESINMDTNDMWLMMRKAYKYAYDQYRDQYNWFFLARPTTFAVIENLKYFLLKKDQSQPFYLGHTVKSGDLEYVSVDGGIVLSIESMKRLNSLLSVPEKCPEQGGMIWKISEDKQLAVCLKYAGVFAENAEDADGKDVFNTKSVGLFIKEAMTNQPNQVVEGCCSDMAVTFNGLTPNQMHVMMYGVYRLRAFGHVFNDALVFLPPNGSEND
The following text describes a protein:
Function:
Molecular adapter that is necessary to form a stable 2-oxoglutarate dehydrogenase enzyme complex (OGDHC). Enables the specific recruitment of E3 subunit to E2 subunit in the 2-oxoglutarate dehydrogenase complex (OGDHC).
Subcellular Localization:
Mitochondrion.
Sequence:
MGSKMASATRVVQVVKPHAPLIKFPNRRDKPKLSASEALGSAALPSHSSAISQHSKGSTSPDLLMHQGPPDTAEIIKSLPQKYRRKPMSQEEMEFIQRGGPE
The following text describes a protein:
Function:
Transcription factor that regulates gene expression during development. May play a role in regulating gene expression in response to osmotic stress.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Tyrosine phosphorylation is not required for translocation to the nucleus. DIF inhibits export from the nucleus. Predominantly nuclear in pstO cells at the rear of the prestalk region in the slug. Subject to crm1-dependent nuclear export.
Sequence:
MSNNNPKKRPLDAISNTFEVKQEEPEFSSDGFNTTNDDLMSLMTFLDNGTGQQNQQNQQNQQPQPQPQPQPQLPQPQSQQPIYNSNTTTVTVKTEGIATSPLSNASSPISTNNNINNNTNNNNNNNNNNNNNNNNNNNNNNNINTATPPAIGVQQNSNIPYSYPIYTDVTGQQTQHQQNIGQNSVNIDPYFQTIDGAQIQQQQLLQQQLQPIQQVNNPQIDQAQIQQQQAQQIQQQQAQIQAQQAQIQQQQLEQQHLQQQQFQFQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHHQQQQQQQQHQQQQQHQQQQQHQQHQQQQHQQHQQIHQNHQNQLNHQNQLNNQNQLNNQNQLNNQNQLNHQNQLNQPTQPQMQQIELPILHQLPVEPQHLHPIPTHINNNGNNNNNNNNNGSNSSNSSNGIGSPDDIIEPNILSSIQHCNNNNLPLPDHLLINTPYGNVLQPHQQIINECLKLHLAQKEQLDKMKIVQKQVLAHPQKETFQMLDNEQNTLKKQIDAEITSLQQIDQTFVLSPPEIRNVIFLLHELTIQSIQLELYHEELQLLVRPQNPPPTIAALVVIEQPFPMVITKCKPLEDDPVVVQLLCGTRTELQMIGKVRATMIVENQQGSKTSSSPKTIETEVVSMDETNRLAKYHLKFLNGTRKNPVTLKFGMQVQVVGGTAVNIESPPTSPFIVITNECQYEESDGTLLKKDSFGNNNEIPWASYANKLQRHFLRATRQDFMKPTRYLSRHELMYIHHQFFGSKPMIPQSSFDSFWIWFGKGLQKLRYQRHVCSMWQSGLIYGFISRQSVEEALRNEEQGTFLIRFSERHAGHFAVGYKVDDPDPEKRIRHYLVKADDTAGAKKTLPDFLSECPQFTKILQLTIDVSTGEPRLRNFPKDVVLEPYYSKRETLPATNGYDSLPTIL
The following text describes a protein:
Function:
FAD-binding monooxygenase; part of the gene cluster that mediates the biosynthesis of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture. The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase prhL (By similarity). Synthesis of DMOA is followed by farnesylation by the prenyltransferase prhE, methylesterification by the methyl-transferase prhM, epoxidation of the prenyl chain by the flavin-dependent monooxygenase prhF, and cyclization of the farnesyl moiety by the terpene cyclase prhH, to yield the tetracyclic intermediate, protoaustinoid A (By similarity). The short chain dehydrogenase prhI then oxidizes the C-3 alcohol group of the terpene cyclase product to transform protoaustinoid A into protoaustinoid B. The FAD-binding monooxygenase prhJ catalyzes the oxidation of protoaustinoid B into preaustinoid A which is further oxidized into preaustinoid A1 by FAD-binding monooxygenase phrK. Finally, prhA leads to berkeleydione via the berkeleyone B intermediate. PrhA is a multifunctional dioxygenase that first desaturates at C5-C6 to form berkeleyone B, followed by rearrangement of the A/B-ring to form the cycloheptadiene moiety in berkeleydione. Berkeleydione serves as the key intermediate for the biosynthesis of paraherquonin as well as many other meroterpenoids (Probable). The cytochrome P450 monooxygenases prhB, prhD, and prhN, as well as the isomerase prhC, are probably involved in the late stage of paraherquonin biosynthesis, after the production of berkeleydione (Probable). Especially prhC might be a multifunctional enzyme that catalyzes the D-ring expansion via intramolecular methoxy rearrangement, as well as the hydrolysis of the expanded D-ring (Probable).
Sequence:
MAIGPKPESIIGSCDHPPQAEAQTGARLAAINGNNSPVSRLKDFTTDPWLTSTDQPQPGSTTNVPYSPPDSTKHARILIVGAGYGGLLFAVRLLQSGFTLEDILLVDSAGGFGGTWYWNRYPGLMCDIESYIYMPLLEETKNIPSQKYVSGEELRTHAERIAEKWKLGARTLFRTTVSDLTWDDNKLQWIATASCSSNERKQAGCTYTINADFAILANGTLSKPKVPDLPGIDDYTGRIFHTARWDYDYTGGSPAIPAMDQLRTKKVGVIGTGSTAVQVIPQLARWAGELTVFQRTPGAVGLQINRETDHAWWRDNVQLAGPEWQRKRCENFNAFITNPYRASLDAEDLVKDGWTKHPSFSVALGGARNLQADFLDLAKKIDKERREIGQQHINSTVRDPATAEALFNPTYGWCKRPCFHQGYFETYNRENVRLVSTPGQGITKLTRNGIMWGHQEFELDLIVLATGYELGSLCPANRARLSIHGRGRVSMSQKWASGPATLHGVMTRGFPNLFFPGTSQAGVTANQSYMFDRAAEHIAYIIQNARPRTAASAVNPKVRIEPSLEAEELWAMETVSRAKAFAATKTCSAGSYTISARLGESVDESQMARHMPWGEGMASYVKILEEWRKKRDMHGLEVVYD
The following text describes a protein:
Function:
Methionyl-tRNA formyltransferase that formylates methionyl-tRNA in mitochondria and is crucial for translation initiation.
Subcellular Localization:
Mitochondrion.
Sequence:
MKQIFITMPHVMLKRGVFSIGLFLTSHHSNCLRLHRTKNIGKVLFAQRQCHVHCQTGQDRRWNVMFFGTDHFSLPHLQLMEESRQNGHLIDKLEVVVPQSTFIKRRGKTRKPSPVWEFCQEQHLTCHQWPLDDNISGFDVGITVSFGHLLPEWLINSFPLGILNVHPSLLPRWRGGAPIQHTILNGDEVTGVSIMRIHPYRFDVGPILLQREYNVPSNSTTKSLTHLLAKKGSELLSEVLHNLTEFIEYEMPQSEEGATVGLKIPNKLAWIDWGATTQEIDRLYRAIGEQMPLKSLFGEEELRLEQMVSPADCSDHPIYEGDEPGLISFPQNKSIIYVRCKDGWVGFCSISPIGRKRMTAKEFYNGYLSGRRRDDEERRCFKNHDATNR
The following text describes a protein:
Function:
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDAPEPQPEPDGGDAPGHEPGGSPQDEFDFSMLFDYVYLNPIEEEPNAHKVASPPSGLAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRGGPQNFLSPAKPAGASGLSPRIEITPSHELMQAGGPLRGRDTGLLVEQPPLPGVAASPRVTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAGPLVAPLPGASPQRSRSPSPQPRDDGAPAGYPPTAGSAVLMDALNSLAADSPCGIPPKMWKTSPDPSPVSAAPSKAGLARHIYPAVEFLGPCEQEERRNSAPESILLVPPTWPKQLVPALPICSIPVTASLPPLEWPLSHQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDIDSCLVYGGQQMILTGQNFTAESKVLFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTSVKVNFYVINGKRKRSQPQHFTYHPVPAIKTEPTDEYNPTLVCSPGHGGLGSQPYYPQHPMVAESPSCLVATMAPCQQFRSGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLALADAHRSVLVHAGSQGQGSAALHPSPAGQQASPVIHYPPAGPQLRCGGRQEFQHIMYCENFAPGSARPGPPPAGQGQRLSPGAYPTVIQQQNAPSQRAAKNGPPVSDQKEVLPTGVIIKQEQNLDQTYLDDVNEIIRKEFSGPPARNQT
The following text describes a protein:
Function:
Has vitronectin and fibronectin-binding activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDL
The following text describes a protein:
Function:
Probable transporter of an ATP-driven Fe(2+) uptake system.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKEITIALVGQPNVGKSSLINALSNAHLKVGNFAGVTVDKMEVGLIHKEHQITIIDLPGTYALNDFTTEEKVTKDFLEKGQYDLILNVVDSTNLERNLALSAQLLDTNKKMLLALNMWDEAQKEGIKINTEKLSKELGVVCVPTSARSKEDRLNTELLLDEIVRLYSQNTTNNENIKVPSQSFKESLKYSQSAQRIAQLVISENQQNASFEHTYKIDKILMHKRYGIFIFLGFMFIIFSLSFLIGGGVQKALETGFKFLSDGIKENVANEDLASLVGDGIIGGVGATVSFLPLIVVLYFGISLLETTGYMSRVAFLLDGILHKFGLHGKSFIPLITGFGCSVPAYMATRTLQNYNERLITLFVIGFMSCSARLPIYVLFVGSFFPSSSAGFVLFCIYILGAVVALVMAKLLKLSVFKGQTESFIMEMPKYRFPSWRMVYFSIYTKSLSYLKKAGTYILVGAILIWFMSQYPKSDAAMKAYKQESLLVNKDTTLSSEAKEEKLKELKTELDKKNLKNSIVGRGGAYLEKVFSPMDFDWRLSVSLVTGFMAKEVVVSTLGVLFSLGDQNEKSDAFRGILRKEVSVPSGIAFIVFVMFYIPCFAATITFGREAGGIKFVAYLFIFTTVVAYAFSLIAFYATQILV
The following text describes a protein:
Function:
Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MSSQDDPAAACPVDHKTREAWLAQARANGTPPANPHTSTPSPPPAPTQAQSSSAVQTSCDSSALDQSTSSPAPTSTSILSQLKLATDREVSTIPRALPSAASAPARPANNERDTAPDKKTGNWIYPSEQMFFDAMRRKSFDPEASDMRTIVPIHNAVNERAWYEIKKWEAGRSDTCGGPKLASFSGLSTSLTPRARWRSLMGYQTPFDRHDWVVDRCGEKIEYVIDFYAGGGSGAKKGEGLNFYLDVRPKLNSWEGWKMRVARYWGF
The following text describes a protein:
Function:
Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles (By similarity). In the germline, required for the trafficking of the receptor RME-2 to the oocyte cell membrane where it regulates the uptake of yolk proteins. Also, plays an essential role in osmoregulation in the embryo, probably by regulating the proper formation of the eggshell.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MRVLFAVFSLIMACQAYDAVLFSNSREIGGTPAAKLVESATAEEPVVFIVNPDFTLGQFSVKANAYTSEPSADYLAKSVKNSNFHESQYFSHQIEATQAQWLSSADQYSAGSPIYIIYGEEWTSMEQLAEQLISKIDNSVGIITSTDAVAHEKSSRVKRVATDEFNSDSENSAAAEANGGFPFPLVIPPYNQTFYSVKPTNGHSCLFYLEGLTVVVEQKKEKVLYYANAYIPGSNFTWAYSETDVTCPNGTIGDFIFKIHLTLENDITGMQGTSKKAFTMKKGDKIDFDLTFTGDLFGYWALNKASASNLAISGYDPYKSASVDGSKVVNGSATQYTKLNSVAGWSLACGQSQAVFFPTNEQSVRIGVALMNTQIQLFNYQNPEKWVESAHFTLQTEDCTGTFSSGSWMGIVSALVLIAGLMFGYVMLQSVQTMDRFDDPKQRQIVINVRE
The following text describes a protein:
Function:
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
Sequence:
MKEVNIDTLISKIPNKYVLTVVISKRARQLFEELKFLKTIARDPLILAMEEIAQEKIAYGEGDDLED
The following text describes a protein:
Function:
May play a role in the regulation of cytokinesis. May play a role in signaling by stimulating protein glycosylation. Induces neuritogenesis by activating the Ras-MAP kinase pathway and is necessary for the survival of cerebellar neurons. Does not appear to play a major role in ciliogenesis.
Sequence:
MEEELCDVFSDCMISPNPDASIANIQRHVHELETLVQLSKSPTYRAESHQRDINFAKDLIVTYFAQLIRQDSVNDDLESAILYGLRYLRNVCVEAPHGQEYLFHVQVHLLTGELILQTLQSRITLQNKSVISIPRICMQILCNMSVQQTFIQNEIWSMCYDRIFYVGLNCSDEVVRAYTCATLYNTLSGQERSLCDPLRGRPIVMAVLELQTCEWREFVIERLLQENFLPDLFDCLENQCHLTLLKHVEVLLKRDISNPYVNGSIYLRQPIIPENTCLYISDKFLSICGVIAQYANTRQFTEEMQLAMKLLDILGYATSLNTLYPNLHNQLLLVRAALELLRSIYEVDQQSDGGIFSKIQDTPTELNNPGSHTDNLKKNLIRLIGNMSYRNRIIQDEIRILGGIPLLLNQCRFDVCNPFVTQWCILAIRNLCDENIENQNVIAELNIKGVVNSTALNELGLEVTMQSGRIRVKQKEHDNASI
The following text describes a protein:
Function:
RNA helicase component of the SKI complex involved in 3'-mRNA degradation pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSKLVDAINEVAVSNKDKIELDGIKDDSFDGHLSITEATYDVDTFLKPSPALSKDWIRKLQKKWDREITYKGLYEYPETLARTQIRFQRHGLEGKIMGYKEVPELIEDLNSKNSSSFLRKPSSKNEFVRGSTSNIPFLADDSDVDAIAGEPSVKMALYGEDGLLQVPPGFSRGLSMTATSTTDNLNDEFDPEKWDTKKVKSSNRNFVTIHELNEHLKNVNSKHSEIDDLLPDKRSIVSLPPSTLNLHKQPDYAHVVDSSAPIENFQQLVPEMALDFPFELDNFQKEAIYHLEMGDSVFVAAHTSAGKTVVAEYAIALAQKHMTKAIYTSPIKALSNQKFRDFKHKFEDVGILTGDVQVNPEGSCLLMTTEILRSMLYRGADLIRDVEFVIFDEVHYVNDLERGVVWEEVIIMLPPHVTLILLSATVPNTKEFASWVGRTKKKNIYVISTLKRPVPLEHYLWVKQNMFKIVDQHGRFLMDGYKSANDALKKPDKPVIAKDNKNSARGRGAARGRGVQTNMMRGRGSAKSVERRDANTWVHLIGHLHKQNLLPVIVFVFSKKRCEEYVDTLTNRDLNNHQEKSEVHVVIEKAVARLKKEDRLLPQIGRMREMLSRGLAVHHGGLLPIIKEIVEILFQRGLVKVLFATETFAMGVNMPAKSVVFSGTQKHDGRNFRDLLPGEYTQCSGRAGRRGLDVTGTVIILSRSELPDTASLRHMIMGPSSKLISQFRLTYNMILNLLRVETLRIEDMIKRSFSENVNQTLVPQHEEKIKSFEEKLSALKKEMSDVDLKEIKSCLLSSESFKEYTKKMHFRAITTANGKRIFKDGRVIVFQQLDFTRTVGVLLGTSIRTNASDCTLEVAYLNPQNNLKRPSDLLAFADAFNDVYDNAIFDESNQFKYGLINLSGIERVCNTILRIDSGGIRDRRGGAFRKLSEQFASIKKFSDLLFEEVNWSKVRDFEFCEAFEKRNFLQNKLSGNPIISTPNFLTHFALAYQEYELESNIDNLSSYISDQNLELLPDYEQRIKVLQELGYIDAERTVLLKGRVACEINSTSELVLTELILENSLADFSCEETIALLSAFVFDEKTEVEPTISPHLQKGKEMILSVAEKVNQIQEHYQVLYFNEGNDFESQPRFGLMEVCYEWARGMSFNRITDLTDVLEGSIVRTIIRLDEVLRECRGAARVVGDSSMYTKMEECQNLIRRNIVFCPSLYM
The following text describes a protein:
Function:
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MAPLRDNLIVGTRVTIAQDADLRGEISVGSGTVIHPKATILALQGPITIGSNCIIEETAVIVNRRSTPIRIGDNNLFEVGCRIEAPSIGSYNVFEMRSKVAQNVKIGSYSVVGAGCIVLPKPIADDQLETVFDDQDQQNYESTAVAGTALAQTGSMPESANERAEQIWDELPDQTVVYGADSRRRLWSGEGAQQQAALHAKHLEYLRDAIPGAHKLKIIQGVRAPATGAPPSTTSSTPTS
The following text describes a protein:
Function:
Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
Sequence:
MIVMEDNFSTKLEDKTYIALGSFDGLHKGHMKLIKEIKKMAKDNGGKSMVLTFKDHPLNTINKDLAPKILLDNPSKVKILKENEVDLVNFINFDKEYMKLCPEDFIKKMIYYYNAGGFVVGFNYRFGYKNLGDIELLDKMSKKFNFNLKVVSPVKYLNEIISSSKIRHILIEDGNVDKAKKMLGRNYFLKGNIVKGKQLGRKLGYPTVNLNYNTKYVLPRGGVYYTLIEYENKLYKGITNVGYNPTVEDKKLNIETHILDFHKDIYGENIVIYFSKRIRDEKKFSSLEELKNQLKKDKSFAKRQSM
The following text describes a protein:
Function:
Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MSGTDKSKAGLSLDGPIVILVEPQLGENIGMAARAMGNFALSRLRIVNPRDGWPNIAAQRAAAGADYILEKVELFDTVGEAVADLDLLFATTARPHDQAKPVVGPEAAAAEISGHVATGGKAGILFGRERWGLTNEEVGLANRIITFPVNPGFASLNLAQAVLLIGYEWFKLATSGELPHAMPERSERASQHQMQAFFDNLIRELDKVEFLRPAEKRDTMLVNLRNIFSRMEPTKQDMHTLHGVVMAIAEGRKGPAKGGVLDGEQATRLRALLAEHGQGGGVPDSGSTVRGLARLLRRNPTDAERLLWQALTRDRRFAGQFKRQTPVGRHIPDFVSFPHRIAIELVNPGEGETIAADRAGRRTWLEARDYRVLEIRAADVERDLESGLTVLQSMMSKT
The following text describes a protein:
Function:
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MADSSVERRLFSFILSSMAFFLIYMSLRTMFAPPLPPEEDAIAEVDGETVEPAEDLVADTDASEPGEGEGEEANEDTDAVERPSSPTWSTLGSMDPTSGYVMLVTLNSRGGGIERIELTERKENGRLKYRRVDVRSGYLGYLAADPTATDLGIRVNVVGPGTPADLATASGVQGGLKPGDIITGFNQNNVNNLSMLREAMLETKPGESATVTVLRNEKSIDFTTTLTEHPLDLIRLAEHGGDDEVEGNLSRLSCLLTVGRVGRREIQSGEKTIEGMVDTGDLIWDASQDGDNVSYQLQLSDSEMKPASGKSVGLQRTYSLKPDSYSLDMDVQIDNRAEEAQELAYRIEGANGITLEGWWYSNKISPNWGGSAARDIVYKTTAEGHELVSGYALLKRAKNESEADDQTLFAPDSAPPARNLSYIGVDAQYFTVAMLPPEGQESLKTFRRAAANIIADPSAVPDNKERAVNASFYLDSAIADVPPGSSLKQSLRLFAGPKQPDVMEAYGLGDCIYYGWFSFVAKPLGGLLHLFSNVGNYALAIVLLTLCVRGLMFPLSRKAAINAQRMQELAPELKKIAEKHKDDMEARVRAQRELQQRVGFNPMAGCAPMFLQLPIFIGLYRTLSVDIELRQAAFASWTTWASNLAAPDMMYYWGDWMWDYLGGRGTGWLGPYFNILPMIVVSLFLAQQKMFMPPATDEQTAMTQKMMNYMTLVMGLFFFRVPAGLCIYFITSSLWGIGERILVKKTLPSKPHFDPATLQGAAAGGGTVDGKVNNSAGANGKKSSDGKPKTMADRLRERLGTPEEEAAPLPKDRKRPPSKKPGNKKRR
The following text describes a protein:
Function:
In the mevalonate-independent isoprenoid biosynthetic pathway, converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP.
Subcellular Localization:
Plastid, apicoplast.
Sequence:
MFLKGYTSNVVLIILTFFILLTKEEKNIKNNISGYCFLNFGLKKNAIIKKREKQNLKLFCYNGIRIGQGYDIHKIKVLDEEYNTYANNDFNKNEQSFKTLTLGGVKINNVLVLSHSDGDIIYHSIVDSILGALGSLDIGTLFPDKDEKNKNKNSAIFLRYARLLIYKKNYDIGNVDINVIAQVPKISNIRKNIIKNISTVLNIDESQISVKGKTHEKLGVIGEKKAIECFANILLIPKNS
The following text describes a protein:
Function:
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MTSPAVDQENIPPMDVTNTTATEPAAKGGKTKKAKEVKAKKKPTAAAAAKKKSVSTHPTYEEMIKDAIVSLKERTGSSQYAIQKFIEEKHKVLSPSFRKLLLLNLKRLVASEKLVKVKASFKIPSAKPSSSPKAVTEKKKPAAAAAVKPKAKGKKVTAAAAAKKSAAVKPKPKAKTTVAPKRKAVAAAAKPKAKAAKTSTVTSPGKKAAAAKKKATKVATKKKTPVKKAVKPKTVKSPVKRASKRGVK