lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Possesses acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates. Exhibits strong acylation activity on lysophosphatidylethanolamine (LPE), and lower activity on lysophosphatidylcholine (LPC) and lysophosphatidylserine (LPS). Exhibits acylation activity on both LPE and LPC. Has a preference for 18:1-LPE over 16:0-LPE as acceptor. Palmitoyl-CoA (16:0-CoA) is a better acyl donor than oleoyl-CoA (18:1-CoA). Among several different acyl-CoA species the best acyl donor is eicosanoyl-CoA (20:0-CoA). Activity is calcium-independent. Its activity is essential for maintaining adequate levels of phosphatidylethanolamine (PE), LPE and LPC in the cells, which is crucial for plant growth regulation.
Miscellaneous:
MISCELLANEOUS: The ratio of isoform 2/isoform 1 mRNA is increased about 15-fold in the nonsense mRNA reducing factor mutant upf3-1; MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Golgi apparatus membrane; Single-pass membrane protein. Late endosome membrane; Single-pass membrane protein.
Domain:
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphocholine.
Sequence:
MADPDLSSPLIHHQSSDQPEVVISIADDDDDESGLNLLPAVVDPRVSRGFEFDHLNPYGFLSESEPPVLGPTTVDPFRNNTPGVSGLYEAIKLVICLPIALIRLVLFAASLAVGYLATKLALAGWKDKENPMPLWRCRIMWITRICTRCILFSFGYQWIRRKGKPARREIAPIVVSNHVSYIEPIFYFYELSPTIVASESHDSLPFVGTIIRAMQVIYVNRFSQTSRKNAVHEIKRKASCDRFPRLLLFPEGTTTNGKVLISFQLGAFIPGYPIQPVVVRYPHVHFDQSWGNISLLTLMFRMFTQFHNFMEVEYLPVIYPSEKQKQNAVRLSQKTSHAIATSLNVVQTSHSFADLMLLNKATELKLENPSNYMVEMARVESLFHVSSLEATRFLDTFVSMIPDSSGRVRLHDFLRGLKLKPCPLSKRIFEFIDVEKVGSITFKQFLFASGHVLTQPLFKQTCELAFSHCDADGDGYITIQELGEALKNTIPNLNKDEIRGMYHLLDDDQDQRISQNDLLSCLRRNPLLIAIFAPDLAPT
The following text describes a protein:
Function:
May be involved in gonadal development.
Subcellular Localization:
Nucleus.
Sequence:
MPSISGDRVALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFETLIQGDFPTHFNHTDVAPNKGLSSTGPLGLSYYNGVNTVQKGRPRKRKSPGPGADLAAYNAALSCNENDGDPMDRDSQYSSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKASDGSNLAGGTPSGPASEISNASMSPSSTPTTLTDLTNPTMPTVTSVLTSVPGSLDVHECRSPSQSTLTSLF
The following text describes a protein:
Function:
Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MGDDDTPVCLSVASCKGVSCWLDKLLLWALTLSITLRNTAVDCRRVDRNGLLSPNLNSSMSVVRMGQNVSLSCSSKNTSIDITYSLFLGKRYLESKRRRGGAVDFHLRISNANESGPYKCKVNDSNSSKYSQNFNFTIIQDESCSSCLLSLLLPGVLLGLILPGLAFLIYLKYKKGCTGKTLKENESKGSGDAPTQGELYANICETQKGSEQLQEIHYTTPVFKEVAPTEQEGLEDRKDDYIYSELTY
The following text describes a protein:
Function:
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKPLPLVTRQGDRIVIVNGLRTPFAKQATAYHGVPAVDLGKIVVSELLARSGISSELIDQLVFGQVVQMPEAPNIAREIVLGTGMSVHTDAYSVSRACATSFQAVANVAESIIAGSVDIAIAGGADSSSVLPIGVSKALARTLVDANKARSLSQKLKLFSRLRLRDLLPVAPAVAEYSTGLRMGDTAEQMAKTYGISREDQDALALRSHQLAAEAWQQGWLHDEVMTAYIPPYREAIIEDNNIRKDSTLAQYAKLRPAFDRQHGSVTAANSTPLTDGAAAVLMMSESKAKALGLPPLGYLRSFAFSAIDVWQDMLLGPSYATPLALDRAGITLADLTLIDMHEAFAAQTLANLKMFASDTFAREKLGRSQAIGEVDMSKFNVLGGSIAYGHPFAATGARMITQTLNELRRRGGGLGLTTACAAGGLGAAMILEVE
The following text describes a protein:
Function:
Candidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation. Represses the beta-catenin pathway (canonical Wnt signaling pathway) in a CCAR2-dependent manner by sequestering CCAR2 to the cytoplasm, thereby impairing its ability to inhibit SIRT1 which is involved in the deacetylation and negative regulation of beta-catenin (CTNB1) transcriptional activity.
Subcellular Localization:
Cell membrane. Cell projection, lamellipodium. Nucleus. Cytoplasm. Note=Colocalizes with actin at the leading edge of polarized cells.
Sequence:
MNSGVAMKYGNDSSAELSELHSAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSMDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSSCSLSVAEVDKHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTSTNRPINPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFAVAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKPGKECADAASPALSLAELRTTCSENELAAEFTNAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL
The following text describes a protein:
Function:
Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, that acts as a regulator of hematopoiesis. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby promoting erythroid differentiation.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to transcription start sites.
Sequence:
MRRKGRCHRGSAARHPSSPCSIKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEIILEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEVLPSTHGTPASASALPEPKVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIINEKRKGDCVSAVSQNMFEFLMDRFEKESYCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGSATFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKESSVKTVRSTSKVRKKAKKAKKTLAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRNTQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQMAMELRLTPLTVLLRSVLEQLQEKDPAKIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHAFEEDFNLIVDNCMKYNAKDTVFYRAAVRLRDQGGVVLRQARREVESIGLEEASGMHLPERPIAAPRRPFSWEEVDRLLDPANRAHMSLEEQLRELLDKLDLTCSMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQAPPTGAGTGGFEDEAAPLAPDTAEEVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDTGLTNGFGGARSEQEPGGGPGRKAAPRRRCASESSICSSNSPLCDSSFSTPKCGRGKPALVRRHTLEDRSELISCIENGNYAKAARIAAEVGQSNMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSEEKLFLVLFFDNKRSWQWLPKSKMVPLGVDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEPASDLSDID
The following text describes a protein:
Function:
Probably involved in exporting SapB from the cell (Probable). Expression of the ram locus (ramA, ramB and ramR) induces rapid aerial mycelium formation in S.lividans.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSPAAGAPGSGPGRRRLPALDVRRFSPVRKSRPVPPRAPGRALEVLVLLCSVAAAVAAVAQPLALGRTLDLLLRDGDAGWWLPLSAALLLGELLLDSATSLFTGRCNATWTASVRTRALRGLLRTAPEHARPYPPGDIGTRLTLNAADAGGAPAARAALAASLITPLGALVALALVDVWVALCVLTGLPALALLLRSFARDTGATVAAYQRTQSLIASRLLEALEGADTIGAAGTGERERARVLAPLAELAAQGRHMWALHGRALGRSGVLVPLLTLAATAVGGLRLAAGELSVGDLLAVGRYAQLTAGVGAAASLLGAIVRAREARRRTRELERMTATVYGTRRLPPNGPGELRLCGVRVLRGGREVLRADGVRVPGGSTVAVVGRSGAGKSVLAAVAGRLIDPDEGYVLLDGVRLDRLTHEALRTEVAYAFERPVLGEGTIAEAVADGARRSSRERVRQAARAAGADGFVRRLPHGYDTPLPRAPLSGGEHQRLGLARAFAHAGRLLVLDDATSSLDTATEHEVDLALRRSVRPGTRLVVAHRPSVADRADLVLWLEDGQVRAVGTHRELWHTAGYREVFGAGAGAGAGAGAGAGADAGAGADAGPGPDSGAATAVGGSGPGPVRRPEPEEARP
The following text describes a protein:
Function:
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
Subcellular Localization:
Postsynaptic cell membrane. Presynaptic cell membrane.
Sequence:
MALSGNCRTYAPPRDQGTILQSFPEVVELNVGGQVYFTRHATLTSIPHSLLWKMFTSKRDSVNDLAKDAKGRFFIDRDGFLFRYVLDYLRDRQVVLPDHFPERGRLKREAEYFQLPDLVKLLIPEEVKQSPDDYCHSDYEEASQGSETRICPSASLMPSDRKWGFVTVGYRGSCTMGRESQADAKFRRVPRILVCGRISLAKEVFGDTLNESRDPDRAPEKYTSRFYLKFKHLERAFDMLSESGFLMVACNSSVTASFVNQYTDDKIWSSYTEYVFYRGPSKWQLSNHCDCCCKNSKVDKEGESGTSCNELSTSSCDSQSEASSPQETVICGPVSRQSNIQTLDRPAKKGPVQILQQSEIRRKSDLLRTLTTGSRESNTSKKKVMKEKLSIEEELERCIQDFMKIKIPDRFPERKFSWQQDLLRKYHL
The following text describes a protein:
Function:
Regulatory protein of the TOL plasmid xyl operons. XylS activates the xylXYZLTEGFJQKIH operon required for the degradation of toluene, m-xylene and p-xylene.
Subcellular Localization:
Cytoplasm.
Sequence:
MPAHALLETRRASTQDIPLEQRLAFWEDYNASILVGLKCSSYSQAGFAATQDNLCLERLRLARIGGNEHVVERDRSMIRAVPKESIFVSLVQGSQSFFYQDNGCNLLQPGELVIYRTDKPYLFGFSGPMRQFIFDIPQDDFAERCLRDFKGPLKIGAESPVQRLLVRTLGERTRDFLDSPHGEDAERYQEEAYDLLASIISDHAGEHRASALGASYLLAAKQYIQQHLDEPALSCERVAAATGVSSRHLARLFAQEGSSPGRYLQERRLERARQLLASPQGRRLDVAEVAYRHGFSSQAHFARAFKARYGMTPSEARGR
The following text describes a protein:
Function:
Function as phospholipase selectivefor phosphatidylcholine. Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic.
Subcellular Localization:
Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Late endosome membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MSLKSETRVNTSTLQKIAADMSNLIENLDTRELHFEGEEVEYDASPGDPKAQEGCIPFSSIYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTSRVPSINLYTIELTHGEFTWQVKRKFKHFQEFHRELLKYKAFIRIPIPTKRHTFRRQNVKEEPREMPSLPRSSENAIQEEQFFGRRKQLEDYLTKILKMPMYRNYHATTEFLDVSQLSFIHDLGPKGLEGMIMKRSGGHRIPGVNCCGHGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFRVKVGRKETETKYGLRIDNLSRTLILKCNSYRHARWWGGAIEEFIRKHGADFLKDHRFGSYAALHENTLAKWYVNAKGYFEDIANAMEEASEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYSKRTLMRLHPNIKVMRHPDHVSSSVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGLSLGSLTAASVESMESLSLKDKHEFHKKEPISKIVDETDMKLKGIGKSRKFSKFSLYRQLHRHHLHNADSISSIDSTSSYFSHCRSHQNLIHGLKPHLKLFHPSSESEQGLTRHSTDTGSIRSVQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIGSVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSQATAHELRYQVPGAVPAKVQLLRSAADWSAGIKHHEESIHAAYIHVIENSKHYIYIENQFFISCADDKVVFNKVGDRIAQRILKAHREGQRYRVYIVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGESSILEQLKPELGNKWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARDLRLECFRLVLGYLSDPSEDLQDPVSDKFFKEIWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPILAKEDALRAEEELRKIRGFLVQFPLYFLSEENLLPSVGTKEAIVPMEVWT
The following text describes a protein:
Function:
May act as a carbohydrate transporter.
Subcellular Localization:
Endomembrane system.
Sequence:
MNKMTGLALGGVVAAILMVLQYAEAQTSYVVGDGTGWRVPQDASTYQNWASDKNFTVGDTLSFIFQTGLHNVIEVSEESYNSCSSANPIGTTYNTGPANVTLNRGGEHYYICSFGNHCNNGQRLAITVSGSSTAFPPATTTAPPPPSSSAPSSFHTTVLPFLFLSAFVFIAF
The following text describes a protein:
Function:
Involved in protein export. Participates in an early event of protein translocation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIALILMQRGAGAAAGSGFGAGASGTVFGSQGASNFLSKSTKWLAVVFFSISLFMAWYATHGARPTDQNLGVMSQSATPAPAAAGELTQPLPQAPAAGAVPTAPSQPLPAAAEPATAPAATPVQSAPTQPAPAAREEKTPEPAQKD
The following text describes a protein:
Function:
Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis.
Sequence:
MASGAPQQNGQTAEETPGFLDTLLRDFPAPLSPESPLPWKVPGPVLTLEEVEGELAEVAMGFLSSRSAPPPLAACLAHEAVSQLLQSDLSEFRKLPEQEEEDGDRGDRAEEKAPVTLLDAAGLARSLFDRLWQACGQWQQQVPAAARAPQRQWLVSAHAIRNARRRMEDRHVCLPAFNLLFGLEDSVDRAYFAVFDGHGGADAARYASVHVHAVAARRPELAADPAEALRAAFRRTDEMFLWKARRERLQSGTTGVCALIAGNTLHVAWLGDSQVLLVRQGQAVKLMEPHRPERQDEKDRIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASWELTGSEEYLLLACDGFFDVVPHQEVASLVRSRLAGPQGSGLRVAEELVAAARERGSHDNITVVVVFLRDPQDLLEPEPDAPRS
The following text describes a protein:
Function:
Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MNRFDRLPRASTIFKVVLLVVAVVVITLASFLIGGNIDWLLPLAGSAEAKSVDQLFRFMAIVGTMITLAIVALLVYSGFAFKRAPDDYSDGPPIEGSLQLEILWTILPIVLVTFLGVYSYDVYLKLIRSNPQTGASHHLGPKSQLREVAQVTDSPELGPKREGQTELTVAVESVQWAWVFTYPQSGGLTTAELHLPVNRPVVLKMTAKDVIHGFWVPEFRLKQDIIPGRTTEIRLLPDRVGEYVLHCTQLCGTYHGAMRATVYVQTAAEFEKWRTTQVAAGERDAAVATVVDPVPLLTPVRSPQTARLLEHLQQPNRGS
The following text describes a protein:
Function:
Neurotoxin that produces dose-dependent hypolocomotion and hyperalgesia in mice. May directly act on the central nervous system, as it is 6500-fold more potent when administered intracerebroventricularly than intraperitoneal.
Sequence:
MEAETLSPPRTGATVSLCFLQANSSIPSFYLCEETTCSVCVDYFKDPVTLDCGHNFCKACLTQTWEKSSNIETSCPQCRGIVSQKNFRTNQSLANIVEKVKILSLQGSKKAKGKERVCEKHQEPLNLFCTDDETFICVVCDRNKEHQDHRRIPLGTGFNDLPDNPERFSPQVFALGHEGFTSGRHFWEVVVEGEGDWAVGVARASVRKKDSVNVQLGDGVWVVGKWRGRYHATSWPSSTDFLLSEKTKRVRVCLNYTSNQVGFYDADTEDQICIFSNVPFSGENALPFFFVKSHRQTTNRGTTLWPK
The following text describes a protein:
Function:
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.
Subcellular Localization:
Secreted, cell wall. Secreted, extracellular space, apoplast.
Sequence:
MSCLLQYNTISNNNNIYIYKHPQSPFIHTLPGSWIPSLKSKARRMGGHDHVVWWMCVVVVLAMGDLVLGMAPRRPVAVPFGRNYVPTWAFDHIKYFNGGSEIQLVLDKYTGTGFQSKGSYLFGHFSMQIKMVPGDSAGTVTAFYLSSQNNEHDEIDFEFLGNRTGQPYILQTNVFTGGKGDREQRIYLWFDPTAAFHSYSVLWNMYQIVFFVDDVPIRVFKNSKDLGVRFPFNQPMKIYSSLWNADDWATRGGLEKTDWSKAPFVAAYKGFHVDGCESSVNTQFCATQGKRWWDQKEFQDLDAYQWRRLQWVRQKYTIYNYCTDRKRLPVMAPECKRDRDV
The following text describes a protein:
Function:
Receptor for the insect diurectic hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSDHNHIDSVNASGSDPLLDLHNLDGIGESVELQCLVQEHIEASTYGNDSGHCLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSSKNATRFCHANGTWEKYTNYDACAHLPAPESVPEFEVIVELPTIIYYIGYTLSLVSLSLALIVFAYFKELRCLRNTIHANLFFTYIMSALFWILLLSVQISIRSGVGSCIALITLFHFFTLTNFFWMLVEGLYLYMLVVKTFSGDNLRFNIYASIGWGGPALFVVTWAVAKSLTVTYSTPEKYEINCPWMQETHVDWIYQGPVCAVLIINLTFLLRIMWVLITKLRSANTVETRQYRKAAKALLVLIPLFGITYLVVLAGPSESGLMGHMFAVLRAVLLSTQGFSVSLFYCFLNSEVRNALRHHISTWRDTRTIQLNQNRRYTTKSFSKGGGSPRAESMRPLTSYYGRGKRESCVSSATTTTLVGQHAPLSLHRGSNNALHTMPTLAANAMSSGSTLSVMPRAISPLMRQGLEENSV
The following text describes a protein:
Function:
Supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone and menaquinone.
Sequence:
MTIAQDLPTVLGLPQIQSLAAPDMAAVDALIRRRLASDVVLINQIADHIISAGGKRLRPMLVMLAGHAAGGSGPEHHQLAAIIEFIHTSTLLHDDVVDESDLRRGRSTANALWGNAPSVLVGDFLYSRSFQLMVELDRMEVMQILADTTNRIAEGEVLQLLHVHNPDTDEAAYLRVIERKTAVLFAAGTRLGALASGADAQVQQCLYDYGMQLGFAFQIADDVLDYAADATDLGKNLGDDLAEGKATLPLIHAIAHSDAATQQRLRQIVEQGDAEAMPEVLTAIRATGGLDYSRQRAAEYAAAAEQALDGLPPSPAVAALRGLARYAVERTH
The following text describes a protein:
Function:
This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. DNA polymerase I, DNA ligase and the flap endonuclease may be constitutively associated with the PCNA heterotrimer forming a scanning complex able to couple DNA synthesis and Okazaki fragment maturation.
Sequence:
MTKQLTLFDIPSSKPAKSEQNTQQSQQSAPVEEKKVVRREWLEEAQENKIYFLLQVDYDGKKGKAVCKLFDKETQKIYALYDNTGHKPYFLVDLEPDKVGKIPKIVRDPSFDHIETVSKIDPYTWNKFKLTKIVVRDPLAVRRLRNDVPKAYEAHIKYFNNYMYDIGLIPGMPYVVKNGKLESVYLSLDEKDVEEIKKAFADSDEMTRQMAVDWLPIFETEIPKIKRVAIDIEVYTPVKGRIPDSQKAEFPIISIALAGSDGLKKVLVLNRNDVNEGSVKLDGISVERFNTEYELLGRFFDILLEYPIVLTFNGDDFDLPYIYFRALKLGYFPEEIPIDVAGKDEAKYLAGLHIDLYKFFFNKAVRNYAFEGKYNEYNLDAVAKALLGTSKVKVDTLISFLDVEKLIEYNFRDAEITLQLTTFNNDLTMKLIVLFSRISRLGIEELTRTEISTWVKNLYYWEHRKRNWLIPLKEEILAKSSNIRTSALIKGKGYKGAVVIDPPAGIFFNITVLDFASLYPSIIRTWNLSYETVDIQQCKKPYEVKDETGEVLHIVCMDRPGITAVITGLLRDFRVKIYKKKAKNPNNSEEQKLLYDVVQRAMKVFINATYGVFGAETFPLYAPAVAESVTALGRYVITSTVKKAREEGLTVLYGDTDSLFLLNPPKNSLENIIKWVKTTFNLDLEVDKTYKFVAFSGLKKNYFGVYQDGKVDIKGMLVKKRNTPEFVKKVFNEVKELMISINSPNDVKEIKRKIVDVVKGSYEKLKNKGYNLDELAFKVMLSKPLDAYKKNTPQHVKAALQLRPFGVNVLPRDIIYYVKVRSKDGVKPVQLAKVTEIDAEKYLEALRSTFEQILRAFGVSWDEIAATMSIDSFFSYPSKGNS
The following text describes a protein:
Function:
Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MAHARISMYMPPDIDPTKAAIAYGCRALSKLNEELQSRDLLTRQKALVALCDLMHDPEYVYEAINIGCLESLKTLLQDDDNLVRIKTTEVLYIMATHYVGRVGFLKHDIIQALSLLLSDHQTLCRENLHQAYKHLAQLPKGAQGIVQSGLIPSLVRKLQKEEDHIQEIILDTLALCLQEDATEALESQAVPCLKEKLLSQNSEIRSKAARALIAISIPLDGKNQVWKNKVIPILVTLLSDTDEEVKANAAGALMHATVTTEGKYAALDANAIEPLLELLSTNPKTKLCLNATKALTMLAEAPEGRKLLLSHVPIFRYLLAHKNEAIQRAAEVAIKVIEWKP
The following text describes a protein:
Function:
Key transcription factor required for motile ciliogenesis. Activates genes essential for motile cilia formation and function.
Subcellular Localization:
Nucleus.
Sequence:
MPVLMSPEIANKFKEKWLMLHPEDQDNVSGSVHFDDSLTSLHWLQNFSILSANPERTPSSGCHPQHLFYYKNQLGGTDSPSSPPAGDTAATGMPQTPGNPTTSCSSLANPYALQQAGHYITGQTNPAEEIDYKTNRHVKPPYSYATLICMAMQASNKTKITLSAIYSWITENFCYYRYAEPSWQNSIRHNLSLNKCFMKVPRQKDEPGKGGFWQIDPQYADMFVNGVFKRRRMPATNFNTQRQSKMLSSPSSSYTSQCNQQMGMGHFQGNKRKQVFPKRGNKLARISKSPLLTSDIKTSDVLRGDFDLASVFDDVLSGNDSTFEDLDINTALSSLGCEMEPSSQIHNQSGYSNEDEQACAYLEANGIIGCNMEDFHHQQHHQQAQVHPQYYEGMFSDQQNQQHPWEIKEEAQPVPLSLDHGYAFCEGFFSEMQLWERGESYM
The following text describes a protein:
Function:
Not required for DIF-induced autophagic cell death and necrotic cell death.
Sequence:
MSETFIHSVSENQIIVNDLENNNDYDNEDNVFIDSSVYNQECFMEILKKLEDGKPIHEVVRFTSHSSYTHTIVKTIQGLFLYVVLKSVNIYGSYYDFQRYIGPSMMIGTYACPLYRVQYRINKNDSTGAIIKYSNNLDECETYFNHLCKVFNVLTKRLSLNSICCGVGLSDSFYLMNTKTIKKSSRTRISFIIGNSKYSQHRKLDGVINDVNSFYCALLGCSFHSDNIVWLIDSDLRTFYDKWYTFLQLVQSFQSYIEVVVYYAGHGRSDNGNLKLIMTDGNPVQLSIIASTLTESIKNSDSLCLFIVDCCRDGENVLPFHYPIESFDDKKNIAVLFACKYGELSYESLELNAGIFTRSFVKTITERKNNNISTICNLTDIAIKRIYKNYSGCSLIGNFDCSLLEF
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).
Sequence:
MNWYPWLNAPYRQLVGQHSTGRGHHALLLHSLPGNGEDALIYALSRWLMCQQRQGEKSCGECHSCRLMLAGNHPDWYVLTPEKGKSSIGVELVRQLIDKLYSHAQQGGAKVVWLPHAEVLTDAAANALLKTLEEPPEKTYFLLDCHQPASLLATLRSRCFYWYLACPDTAICLQWLNLQWRKRQIPVEPVAMLAALKLSEGAPLAAERLLQPERWSIRSALCSGLREALNRSDLLSLLPQLNHDDAAERLQWLSSLLLDALKWQQGAGEFAVNQDQLPLVQQLAHIAATPVLLQLAKQLAHCRHQLLSVVGVNRELLLTEQLLSWETALSTGTYSTLPSL
The following text describes a protein:
Function:
Acts as a protein folding chaperone for elongation factor 1-alpha.
Subcellular Localization:
Nucleus.
Sequence:
MADNTNTNVPVHDDKRQKTEEDAEMFQSVGDHASNVDNQVDSQGLRKTGAEDAEGHPVQEIESFCVNCEKTGITRLLLTRIPYFREIVLMSFECPHCHLKNSEIQPAAQVSEKGSKYMLRVEKKEDLARQVVKSDSGNVKFVELDVEIPAKRGQLTNVEGLLTQLAEDLESDQPVRQHVDPETHAKIEEFLAKIRGTIEGDEQRYPFTVQVDDPAGNSWIEYVPGEPSSKWSHVEYFRTKAMAKALGLSVQEDDTPARNQSVAQAVNDAAPSITAASDTITTADGSEIENMHSEVQTFESSCPSCFSKNCPTNMKVVNIPHFKDVIIMATVCEDCGYKSNEVKTGGEVPEKGKRTTLLCDDPEDLTRDILKSESCRLHIPELDLDLTAGTLGGRFTTIEGLLNQVHDELDERVFTQTSDSMTVETEQRWRTFLARLKSAAEGKIPFTLVMEDPLAASYIQNPFAPDADPNMNHEDFERTDEQNDDLGLKDMNVESYQEQPKEEAN
The following text describes a protein:
Function:
Component of SCF(EBF1) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (probably including EIN3 and EIL1). Regulator of the ethylene signaling cascade by modulating the stability of EIN3 and EIL1 proteins. Confers insensitivity to ethylene.
Subcellular Localization:
Nucleus.
Domain:
The F-box is necessary for the interaction with ASK proteins.
Sequence:
MSQIFSFAGENDFYRRGAIYPNPKDASLLLSLGSFADVYFPPSKRSRVVAPTIFSAFEKKPVSIDVLPDECLFEIFRRLSGPQERSACAFVSKQWLTLVSSIRQKEIDVPSKITEDGDDCEGCLSRSLDGKKATDVRLAAIAVGTAGRGGLGKLSIRGSNSAKVSDLGLRSIGRSCPSLGSLSLWNVSTITDNGLLEIAEGCAQLEKLELNRCSTITDKGLVAIAKSCPNLTELTLEACSRIGDEGLLAIARSCSKLKSVSIKNCPLVRDQGIASLLSNTTCSLAKLKLQMLNVTDVSLAVVGHYGLSITDLVLAGLSHVSEKGFWVMGNGVGLQKLNSLTITACQGVTDMGLESVGKGCPNMKKAIISKSPLLSDNGLVSFAKASLSLESLQLEECHRVTQFGFFGSLLNCGEKLKAFSLVNCLSIRDLTTGLPASSHCSALRSLSIRNCPGFGDANLAAIGKLCPQLEDIDLCGLKGITESGFLHLIQSSLVKINFSGCSNLTDRVISAITARNGWTLEVLNIDGCSNITDASLVSIAANCQILSDLDISKCAISDSGIQALASSDKLKLQILSVAGCSMVTDKSLPAIVGLGSTLLGLNLQQCRSISNSTVDFLVERLYKCDILS
The following text describes a protein:
Function:
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer.
Domain:
Each ALS protein has a similar three-domain structure, including a N-ter domain of 433-436 amino acids that is 55-90 percent identical across the family and which mediates adherence to various materials; a central domain of variable numbers of tandemly repeated copies of a 36 amino acid motif; and a C-ter domain that is relatively variable in length and sequence across the family.
Sequence:
MKTVILLHLFFYCTIAMAKTISGVFTSFNSLTYTNTGNYPYGGPGYPTWTAVLGWSLDGTLASPGDTFTLVMPCVFKFITTQTSVDLTANGVKYATCTFHAGEDFTTFSSMSCVVNNGLSSNIRAFGTVRLPISFNVGGTGSSVNIQDSKCFTAGTNTVTFTDGDHKISTTVNFPKTPQSSSSLVYFARVIPSLDKLSSLVVASQCTAGYASGVLGFSATKDDVTIDCSTIHVGITNGLNSWNMPVSSESFSYTKTCTPNSFIITYENVPAGYRPFIDSYVKKSATATNGFNLNYTNIYNCMDGKKGNDPLIYFWTSYTNSDAGSNGAAVVVTTRTVTDSTTAITTLPFDPTVDKTKTIEVIEPIPTTTITTSYVGISTSLSTKTATIGGTATVVVDVPYHTTTTITSIWTGSATTSSTYTNPTDSIDTVVVQVPSPNPTVTTTQFWSGSVPTTETVTTGPQGTDSVIIKEPHNPTVTTTEFWSESFATTETVTNGPEGTDSVIVREPHNPTVTTTEFWSESFATTETVTNGPEGTDSVIVREPHNPTVTTTEFWSESFATTETITTGPLGTDSIVIHDPLEESSSSTAIESSDSNISSSAQESSSSVEQSLTSADETSSIVELSSSSDIPSSSIGLTSSESSTVSSYDSYSSSTSESSIASSYDSYWSSSIESSTLSSSDRYSSSISDTTSFWDSSSSDLESTSITWSSSIDAQSSHLVQSVSNSISTSQELSSSSSEESSTSATDALVSSDASSILSSDTSSYYPSSTISPSDDFPHTIAGESDSQSISFITSTVEISSDSVSLTSDPASSFDSSSSLNSDSSSSPSSDQSDILTSSSFSTLVVPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKLSVFVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELTTTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDGESTVEIPPVTDTTTVSSVSVHSIEASTATLGENSFSKVASAPVNTETSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGSTYANSGSTNNLMTESQVAAPTDSTSVLTANPVVTSTFDDKSSAAVNQPSKTKSIEESIGSLDSVNETNNGFIATLSQSEAPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
The following text describes a protein:
Function:
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
Sequence:
MWLPSKRRFCGSSALATSPFCGNHDPAAGEKRVPCPVDPSHTVLHNDVAAHVKRCQATKHMKFSEEQPYYCKGINAGSDGEEDGRASRDDHDCSEESRAAAEIPPAEIPPADPPRENGACGKTEQRVEFLSSAAKRSAITALSERQFLELVRRIESAHEASRSETVEESFLQPPQCLQWWDRNRDKRLPFKEKHVSQQASMLGNFEAFGLLKRDGAGDANDDSDSSKAGGDCESRAFVEFGAGRGYLSHMLCDSYGVSSVVLVERKAYKYKADRTLRQLTGVSVERLRTDIEDLSVRGVPALQGRRYVAVSKHLCGPATDLTLRCCLNEAGSSDPTGLDSSPVLEGVGIATCCHHLCQWRSYVNKPYFREIGFSEADFNMITWLTSWAVNESGDHAEVEIPEAQKIPDHRVVPDGTSPGAQIFAPRLSEVMDAMEDGARAELGRKCKHLIDFGRLLFLRRHGMSAKIVKYISATVSPENKLLLGRRIFA