lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Pleiotropic ABC efflux transporter involved in the protection of the cells against a wide range of toxic compounds.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MENTSVSKPSPGAEVPVETQKESATGMATPSPSTASENDDGSNDKETKTPLFASYAVCLGSCLHMLNWRSDSYLANPLVRDRSPWLASLDPRPWMCNGIRNGRSHFHMCTAIPNKSQTLPLMNVIFGKLVGDFNAYFIPDSGVTDLYLIYLFIGKFVLTYVYMLCFRMISLKASSSLRLSYMSSLFSQPVSKLDAISVGSVTNTITSLSNTMQQSVSDRLAMLFQSVALLIAAYAVAFRYSWALTLVVSSAILFVVLAFSVTLPIMISGQRSVDLADEQHASIASEVFGSIRTVFSLGADGPLSRKYSEWVDEARKRGRRMAFVTGIHLAILFFSMYCSFALAFWFGIKLFREGNIPNVGTVITVFFSVLLVVTIMGGIISPLMAISKAVSASAAFFSVIDAEKLPSGGFKEPEVSSQSDIVFENVTFAYPSRPSVSVLKGFSAVFQRGKTTAIVGPSGSGKSTIVTLLERWYQLDPSGDGEKMSGEIRINDRNINSLDLKWWRTQIGLVQQEPFMFNDTVYNNVAFGLIGSQWEDASEEVKRGLVEKACKEAFVDEFVQRLPSRYSTLIGENGLTLSGGQRQRLTIARGIVSNPPILILDEATSSIDVRGERIVQAALNRVSKDRTTIMIAHRLSTVRNADRIIVLRDGENVEEGSHEELLKREGVYSGLVKAQLLGTFYGADGFEDSEHNEWAASEEKNEGELNSIPEEAPAKKMGGFMSLSAILYEQRAYWMLYIVILAAAAGSGSGFALQSYLFAKLIEVFNFTGQRLIDAANFWALMFFVLALAVGACYFILGSCSVIVSHFIASFYRKDYFTSLIRKPVPFFDSASNSSGTLTSNLSSSAKQLQELFSVNGVFPLVSIFVILGCISISFAFGWKLAAVAIFAALPFIATAANLRIRYETQFELMNAKVYAESSAFATEAIKAFRTVSACTMEGFILERYKVLLTEQREKALKKAWLACAVFAFSDSVDFCAMALTFWYGGKLLGSREYDLVQFFVVYIAIIQGGQMAGMMFSSGADLAQAKASAARIFMARTPSATISTQDPAITPPDARAPSDASLEFCSVSFRYPFRKAPVFADLNLRIESGQFVAFVGPSGCGKSTLISLIERFYEPTEGSILFGGVPINTLDIVSYRRNLSLVAQDPKLFNATIRENLCLGIDPDNHEQDHDRDLEERMISACTSAEIHPFILSLPDGYNTALGTNASSSASLSGGQKQRLCIARALLRNPRVLLLDEATSSLDSQSEKLVQQAMEKLAESRDLTIIAVAHRLATVQKADVIFVFGEDGTKAGSRVLEKGTHSELLEMRGVYWQMCQAQALDR
The following text describes a protein:
Function:
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).
Subcellular Localization:
Nucleus.
Sequence:
MGPVMPPSKKPESSGISVSSGLSQCYRGSGFSKALQEDDDLDFSLPDIRLEEGAMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFFKRNGALLQDPDIDAASAMMLLNTPPEIQAGCNPQTKSGWCGDLGVCMENGQDLMAAVPPGVIQNGARVLSRGLFPGVRPLPITPIGVTAAMSRNGITSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSSSADDHYEFATKGSQEGSEGSEGSFRSRESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETTKN
The following text describes a protein:
Function:
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
Sequence:
MNALAGKTVLITRAQHQAKQMSVAVKEKSGIPLEIPLLRMEGMSHRQIQHIEEQLHSYDWVIFTSRNGVAFFLDSLKKKLPLTIRIAAVGVKTKLELEKRGYQVHFVPTSFVAEAFAEEFLKELSGNERILFPKGNLAREVIPVALREIGVSLDELIVYGTKVNIEKKQELIAALKLGKVDIITFTSPSTVTSFVRLLEGTNWREWTKKCTIACIGPITEKEASLYFPSVIVPKEYTVEALLQYVCESIK
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MGDLSALQEVLTSGERMNGVQEFYRDATILITGGTGFIGKVLLEKLLRCFGVKTVFLLVREKCNKTVDERLDEVFEDVIFDAIKSSPHNGKPLFAKVIPIEVNFQSDQVISSSDHQRLLAAQVEIVFNVMASVKFNEDIETALDTNVLSSRKLFLLAQQLPHIRSIVHVSTFYSNCHRSHIEERIYEELPFGGFENILALFRHLTPKEKDQLKPIILGPMPNSYTFSKRCAEVMIQQQFSGLPIAIFRPPIVSSAYSEPSPGWVNNFNGPAGMVVPVIRGQVYWCYGADDAAVHMVPVDYCVNALLAVGWENGQRKRMQESTMSKVVPVYNYAFRDNVVRNRDIGALLALGIDSTLGRIFGRYTIHVTSSLFMRQLFINWLLIQAYVSDTFNKLTGKKAKNYDLIKRVVALEDSTSYFRCNSWTTENDNIRQLWDRLSEDEKRLLPFDVETLDWKYYFRHFVKGVADALNRHCLARQRACSPKPCC
The following text describes a protein:
Function:
Self-glucosylating initiator of glycogen synthesis. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase.
Subcellular Localization:
Cytoplasm.
Sequence:
MARPLEDVYCTLLMSDSYLPGAAVLAHSLRDAGTKKKLAVLITLETLSADTITQLKELYDYLIPVERIRTPSPANLYLMGRPDLSFAFTKIALWRQTQFRKIVYLDADVVALRALDELFDIEAPFAAAPDIGWPDAFNSGVMVISPDMGEYWALQTMAATGDSFDGADQGLLNQYFEHRPWQRLKFTYNCTPNAEYQWEPAYRYYKRDISAVHFIGKEKPWSSSRTSGPGVYGELLSRWWQVHDRHLRRDASGTTHLQIQSSAPVPNIVIEPEASVTTTEPPMTDPGEVVENIDQGVLEPVPTTELRKFSAPDMEWDATKFEPPAQSRPEAANFPTAQYTFSDSRQLFQAPHAYPAPPRDMWYQVPEHRPKPAEAPKPIFPWEQQADRPKPTRVFAEDIQPQPTREPPSPTHAFSTVHYDNSELEASAGSSDGVTSPEALGSPKSADQQWQSFQQNNANAWDNMPGIENYVRAIMGSQGGKRTNTQILQQTTGTEELHSPLLERKNRRESLILTDFPSAIERPSLPVTPAPIRRPTFWGEERNETGELPAAKGVPDQTEWVCPQCGFSSPSDSFTASAKDNKV
The following text describes a protein:
Function:
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAPAVDRKGYWGPTTSTLDWCEENYVVTLFVAEFWNTVSNLIMIIPPIFGAIQGFRDRLEKRYIAAYVALTVVGMGSWCFHMTLKYEMQLLDELPMIYSCCIFVYCMFECFKTKSSINYHLLFTLVLFSLIVTTVMYGMLVFALVLRSIYIVTWVYPWLRGLGYTSLTVFLLGFLLWNVDNIFCDSLRNFRKTVPPVLGVATQFHAWWHILTGLGSYLHILFSLYTRTLYLRYRPKVKFLFGIWPMVMFEPQRKH
The following text describes a protein:
Function:
Converts sphingomyelin to ceramide.
Sequence:
MGLLWCAVMAMAVALAFAHPQQPSTYHPDDVTYPGSVTVFTVPAAFPTSVFSSYYVKPGPTNQPQPVLYDPVLNITFPFNLTDPKHVPDSNDDPVIFPQPIANISDATGEAIASAAVSEISRIFKSNNVGGSTTCSKCIAALAVGQMVARLAPTHFPSGMVSLCHSLKFSTYSSCELTYGPNGSGASWAQILAKADVAGLDGKYICSYLHKNVCEYPTVTSAKAVFPKPKPKKPAEPRRSGKKVKVLHLSDLHLDPRYSVGSEANCTSYMCCRYSEPPANGTVPEISVSAPLFGYYKCDSPFYLALAALQSIGPLTGTSAKNPPAFSLYTGDLIAHDDENQASRAYVEATEVAIWETFKAYIGGPIYTALGNHDTTPADYEAPHAIDNNSTLGSQFSWNYAHVSSLWAHYNWLPSSVAQQASTHYAAYAVSPPHHPNLKIITLNSDLYYQHNPFALLNASNPDYSGMFSCLITELQAAEDAGQRVWIVAHIPTGWDGGSALPNSADYFYQIVERYSPHVIANIFFGHSHEDQATIYYRNNGTAQTREEALVTGWVGPSLTPLQNLNSGYRMYEVDTGSWEVMEAFTFYSDVGSYTNLSSSVDGEGNGGQGEGPVFKLEYSTRATYGPAVNWPSDAPLNATFWHGVTEAMERNRTLAELFTQYQGKSSAKSKKCETEECTKAKICYMRSGSTALGKQCKQGYGSVQ
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MLSDHIMSLFTVNRYLGESPVESGASPGQSILDKINAKAKAREEQRKQTPLKLKESSPAQESKVKHATPRRTAKDESPSSQTPGTDSVKRKKKKKKLVVQQESSDAVGHGDDGGDTLLPQVGEMIKEDEKRDEDVTVAVRDAVMLTAKERKQRVIDQGLVPKDSVVTIKKKKGKRKNEEGKVKEGEDRSEISEMSKKTRLEMKDGESLDLSPSGTKRIKEKLKKNVGKKDRTDKNQTTKDEELNMVSKDESRKEEEEEEQMEVDKEEEEEDGGTVEEEKVESEDDKEPHNFVILGDFERKHKKKKVQEALPDWLARPSVIQQSLTNDLQPVNSIKGLDERLVTALAYMGVEKFFPVQQHVIPVLLESLRDGIHTGHAGYRPRDLCISAPTGSGKTLAYAIPIIQALMNRVVCRVRALVVLPTRDLATQVYKIISALCKATPLKPVLIGGTKKFAQEQSLLVREIDGELHSLADIVVATPGRLVDNISQTAGFNLQHLRFLVIDEADRLMEHISQDWIAQVEKSAYTPLYDNGTTLPTFTSNRQRPGPLTINRSSSFQLPLQKLLFSATLSQNPEKLTQLRLFQPRLITTATSSRAPPISAWHLDGEKEGVKEEGKEKDEGRTDFVGKYTTPVGLSEYFVQCTAGEKPLVLQHFLLNLYFKQVLCFTNSVQTTHRLYLLLKLMGDVEVSEFSSNLSQSERQNILKQFKAGKIQILVCSDAMARGMDIENVRCVISYDLPPHLKTYIHRVGRTARAGRGGTAFSFIRKKEVNDFKHMLKNAGKDGIQRHTVSSNHLEALAPAYTEALTKLSSMLREQKAHQY
The following text describes a protein:
Function:
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
Sequence:
MHSSPSAGKQRVALVMQYLGTHFHGWQRQPNFSSIQEEVELAIAKVVGQPVTLHGAGRTDAGVHAAAQVAHFDDPVGQIPPHRWSKILNGHLPQDIIVRGSAAVDSHWHARFSALWRRYRYSIYTDQWPNLFADQFSWHYYRFPLQEKTIQAAMEPLLGKHHLAAFHRAGSARRHSWVEVQGVECYRRGPMVYLEIQANGFLYGMVRLLVGMLAEVGSGQRSLTDFNDIWVNQRRDLVKYAAPAKGLCLLRVGYENFPLPDSLWFDSQPLWQFTG
The following text describes a protein:
Function:
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with regulatory proteins of cell cycle progression including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
Subcellular Localization:
Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Nucleus, nuclear pore complex.
Sequence:
MAKRVADKELNDRNWDQEDEGEEAGTFSVASQDVLKNRAIKKAKRRNAAAEGESGGNFKGFKGFTLSASGSAGGFAGFGNGSGLKPLSSLTNGNGSSSSTPSFSGFSSTSDSKATTESLTFNGPASSQPQSNDVSRQSNGVTQSSSAPSSQSSSRCSREYNRQLTALNCSVRDWIAKHVNDNPLCDLNPIFKDYERHLATIEEKYGGSSDSGSESEPGSRQAEAQPGSVPGSSGAPQQKATAALFSFSKEEKESSSAPAPSAPAPNVTFNFGQKVDSSALGPLPASSTASFSFSSQGTGSLFGSQGTTPASTFSFTSAKTSAPSEEKTKDENAGDEESEEPPKPVVNEVKEDDAFFSKKCKLFYKKENEFKEKGVGTLHLKLVADKKTQLLVRADTNLGNILLNILLQSSMPCTRMGKNNVMVVCVPNPPVDEKNPTAPVPILIRVKTAEDADELHKLLLEKKA
The following text describes a protein:
Function:
May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Subcellular Localization:
Cytoplasm.
Sequence:
MPRGRASRTSIQSELHRDRRRPEITIVAAEPLRPASWFPGTPPPGLGFPTSSAAGSWRPNELVPAELPPSYEQVIKEINQVQVNTTNNNNAAATPRHTITSATQTDFSEEIDNDLPQTLQAPLKPLQPFSAVSSGNLPTNVAPLIVFDISEEPNCPENPSATRCPVPKPRSKSNLRPIPRDSHIKEQSQQKISPAAVGEESSPGRPQSLLDNASTSDSQAVMNIMNTEQSQNSIVSRIKVFEGQTNIETSGLPKKPEITPRSLPPKPTVSSGKPSVAPKPAANRASGEWDSGTENRLKVTSKEGLTPYPPLQEAGSIPVTKPELPKKPNPGLIRSVNPEIPGRGPLAESSDSGKKVPTPAPRPLLLKKSVSSENPTYPSAPLKPVTVPPRLAGASQAKAYKSLGEGPPANPPVPVLQSKPLVDIDLISFDDDVLPTPSGNLAEESVGSEMVLDPFQLPAKTEPIKERAVQPAPTRKPTVIRIPAKPGKCLHEDPQSPPPLPAEKPIGNTFSTVSGKLSNVERTRNLESNHPGQTGGFVRVPPRLPPRPVNGKTIPTQQPPTKVPPERPPPPKLSATRRSNKKLPFNRSSSDMDLQKKQSNLATGLSKAKSQVFKNQDPVLPPRPKPGHPLYSKYMLSVPHGIANEDIVSQNPGELSCKRGDVLVMLKQTENNYLECQKGEDTGRVHLSQMKIITPLDEHLRSRPNDPSHAQKPVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYVKVIIDIPEGGNGKRECVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPVEDYPTSGANVLSTKVPLKTKKEDSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQFLQIS
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of D-ribitol-5-phosphate and D-ribitol-1-phosphate. Is also able to dephosphorylate 5-amino-6-(5-phospho-D-ribitylamino)uracil, and thus could be involved in the riboflavin biosynthesis pathway.
Sequence:
MIKNIVFDFGGVIVDIDRDKAVQAFIKLGLADADTRLDKYHQTGIFQELEEGKLSADEFRKQLGDLCGRELTMEETKQAWLGFFNEVDLRKLDYILGLRKSYHVYLLSNTNPFVMSWACSPEFSSEGKPLNDYCDKLYLSYQLGHTKPAPEIFDFMIKDSHVIPSETLFVDDGSSNIHIGKELGFETFQPENGADWRQELTVILNS
The following text describes a protein:
Function:
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.
Sequence:
MSSLALSSLKVPPVLLLSPPPPAKLIHLSSFSSFLLNTGIPRATSREFFSVVKVSSRPISTMATDKEIVGSVKEQLAKLFEESLRAAFPDIEDVHPMIAICNDSRHGDYQCNNAMSLWNKIKGQGTQFRGPQPVGKAIIDNLPASEMIERCSTAGPGFINVVLKKQWIAKSIERMLIDGIETWAPKLPVKRTVVDFSSPNIAKEMHVGHLRSTIIGDTLARMLEFSNVEVLRRNHVGDWGTQFGMLIEYLFDKIPNWEAASAQAIGDLQAFYKASKQRFDNDPDFKERAQKAVVSLQGGEEKYRKAWTQICEVSREEFQRVYQRLGVHLEEKGESFYNPYIPKALDLLNNKGLIQESEGARVIFIEGKKIPLIVVKRDGGFNYASTDLTALWYRLNEEKADWMIYVTDVGQREHFEMVFAAAKLAGWLPQNENDFPKASHVGFGLVLGDDGKRFRTRSTEVVKLVDLLDEAKSRCKLALEERGKATEWTAEELEQTAEAVGYGAVKYADLKNNRLTNYTFNFDQMLSDKGNTAVYLLYAHARICSIIRKSGRDIEELKKVGGIVLAHPDERALGLHLLQFAEIVEEACINLLPNLLCEYLYKLSEDFTKFYTNCQVVGSAEETRRLLLCEATAVVMRKCFYLLGITPVYKI
The following text describes a protein:
Function:
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIERLKKVSLPALSAFILFCSCHYGRILGVICFDIGQRTSDDSLVVRNRHQFKWFCLSCRLISVTAVCCFCAPYVADIEDPYERLLQCFRLSASLICGICIIVVQVCYEKELLRMIISFLRLFRRVRRLSSLKRIGFGGKREFFLLLFKFICLVYELYSEICQLWHLPDSLSLFATLCEIFLEIGSLMIIHIGFVGYLSVAALYSEVNSFARIELRRQLRSLERPVGGPVGRKQLRIVEYRVDECISVYDEIERVGRTFHRLLELPVLIILLGKIFATTILSYEVIIRPELYARKIGMWGLVVKSFADVILLTLAVHEAVSSSRMMRRLSLENFPITDHKAWHMKWEMFLSRLNFFEFRVRPLGLFEVSNEVILLFLSSMITYFTYVVQYGIQTNRL
The following text describes a protein:
Function:
Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPFSIYLLHLAAADFLFLSCRVGFSVAQAALGAQDTLYFVLTFLWFAVGLWLLAAFSVERCLSDLFPACYQGCRPRHASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRYHVASVTWFLVLARVAWTAGVVLFVWVTCCSTRPRPRLYGIVLGALLLLFFCGLPSVFYWSLQPLLNFLLPVFSPLATLLACVNSSSKPLIYSGLGRQPGKREPLRSVLRRALGEGAELGARGQSLPMGLL
The following text describes a protein:
Function:
Transcriptional regulator and common SMAD (co-SMAD), required to regulate entry into a developmentally arrested larval state known as dauer, in response to harsh environmental conditions. Probable component of transcriptional regulatory complex with SMAD protein daf-5. Acts antagonistically to SMAD signaling downstream of TGF-beta-like daf-7 signaling. Binds to the 5'-GTCTG-3' motif found in regulatory regions and may modulate the expression of genes involved in TGF-beta-like daf-7 and Notch lag-2 signaling. May regulate gene expression outside the dauer pathway.
Subcellular Localization:
Cytoplasm. Nucleus. Chromosome. Note=Localization observed during mitosis.
Sequence:
MGDHHNLTGLPGTSIPPQFNYSQPGTSTGGPLYGGKPSHGLEDIPDVEEYERNLLGAGAGFNLLNVGNMANEFKPIITLDTKPPRDANKSLAFNGGLKLITPKTEVPDEHTPMMSPVNTTTKILQRSGIKMEIPPYLDPDSQDDDPEDGVNYPDPDLFDTKNTNMTEYDLDVLKLGKPAVDEARKKIEVPDASAPPNKIVEYLMYYRTLKESELIQLNAYRTKRNRLSLNLVKNNIDREFDQKACESLVKKLKDKKNDLQNLIDVVLSKGTKYTGCITIPRTLDGRLQVHGRKGFPHVVYGKLWRFNEMTKNETRHVDHCKHAFEMKSDMVCVNPYHYEIVIGTMIVGQRDHDNRDMPPPHQRYHTPGRQDPVDDMSRFIPPASIRPPPMNMHTRPQPMPQQLPSVGATFAHPLPHQAPHNPGVSHPYSIAPQTHYPLNMNPIPQMPQMPQMPPPLHQGYGMNGPSCSSENNNPFHQNHHYNDISHPNHYSYDCGPNLYGFPTPYPDFHHPFNQQPHQPPQLSQNHTSQQGSHQPGHQGQVPNDPPISRPVLQPSTVTLDVFRRYCRQTFGNRFFEGESEQSGAIIRSSNKFIEEFDSPICGVTVVRPRMTDGEVLENIMPEDAPYHDICKFILRLTSESVTFSGEGPEVSDLNEKWGTIVYYEKNLQIGEKKCSRGNFHVDGGFICSENRYSLGLEPNPIREPVAFKVRKAIVDGIRFSYKKDGSVWLQNRMKYPVFVTSGYLDEQSGGLKKDKVHKVYGCASIKTFGFNVSKQIIRDALLSKQMATMYLQGKLTPMNYIYEKKTQEELRREATRTTDSLAKYCCVRVSFCKGFGEAYPERPSIHDCPVWIELKINIAYDFMDSICQYITNCFEPLGMEDFAKLGINVSDD
The following text describes a protein:
Function:
Probable histone methyltransferase. Histone methylation gives specific tags for epigenetic transcriptional activation or repression (By similarity).
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MKLSTDAHSEIEGDAAHGNVLCNSASDSLTATDEVAAGNDESVATEGDDVEIPRDTNNSTPVRLLDKPGQNPVQNGAQPAAEESELESQRQTPVQKQQQQRVSMVNRKRDLINLQSALSPKYIGYANANSPTPLSDSDDTIRTTRRRVNQAAALNNSSAGETLAHDNASPRTPGGGGGGGGDDSANQLLSKTYMSPIEKLLIKNGASSPNSTGFEAGSEDLGIRPIVRKHVKRKMKRVPKAKVTLELDEKNQQEVDEKSVKTEPIDEEVDRTDEAPTQEAQTTAISIKSETEAEHKAAVDVHIKQEDTIRLDIVNNPVESTSIVITEEPKDLEKSTEELAFALPLASSTEVDLKSPPDLSSTALATSIKSPSSVSIDSAKGLSIVTDPGWPTYQVGDLFWGKVFSYCFWPCMVCPDPLGQIVGNMPSHPQRSSLDNANVPIQVHVRFFADNGRRNWIKPENLLTFAGLKAFDDMREELRIKHGPKSAKYRQMVPKRTKVVIWRQAIEEAQAMTQIPYSDRLEKFYQTYENVVTLNRQKRKRTKYMMQDTSDVGSSLYDSTDNLHNKQGTQLLAVKRERSESPFSPAFSPVKSKNEKRAKRRKLSNGTEADTGSNSMAVTPSQTETTVDSSAYENPEFRQLLSAVMEYVMMNRSDEKVEKVLLSVVSNIWSLKQIQLRELERDLASGEIEEPLGSSVVGRGSGVGTIKRLSNRLMTMMVRRSMTPVVTPSTTPAPSEPDRRLSEPPKTKKPVNRPIEEVIEDILQLDSKYLFRGLSREPICKYCYQAGSDLVRCSRTCSSWLHADCLERKVTGAPMPKIGSRKALVIPPTSKSPSPDEDHVTADAKEVVAVGTSLVCHECNVGEPEGCVICHQVESPAVPSTPRKEDSSSHTPIEDKLLTCSQPMCGKRFHTSCCKYWPQASSSKHSARCPRHVCHTCVSDDPSGKFQQLGSSKLAKCVRCPATYHQLSKCIPAGTQMLNTTNIICPRHNIAKADAHVNVLWCYICVKGGELVCCETCPIAVHAHCRNIPIKTNESYICEECESGRLPLYGEIVWAKFNNFRWWPAIILPPTEVPSNILKKAHGENDFVVRFFGTHDHGWISRRRVYLYIEGDTGDGHKTKSQLFRNYTTGVEEASRFLPIIKARRQEQDMERQSGNKLHPPPYVKIKTNKAVPPLRFSQNLEDLSTCNCLPVDEHPCGPEAGCLNRMLFNECNPEYCKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQKQRDRDENYYFLGVEKDFIIDAGPKGNLARFMNHSCEPNCETQKWTVNCIHRVGIFAIKDIPVNSELTFNYLWDDLMNNSKKACFCGAKRCSGEIGGKLKDDAVKAHAKLKQMRRAKASAVRIHVKPKKTPKVKHISADDEPMDAKDE
The following text describes a protein:
Function:
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes (By similarity). Within the HOPS complex, contributes to the normal development of gut granules in the adult intestine. May mediate the tethering of autophagosomes with lysosomes. Has a role in the negative regulation of apoptosis. Required for uptake of exogenous dsRNA which is used in experimental RNA silencing.
Subcellular Localization:
Endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle. Cytoplasm, cytosol.
Sequence:
MDETHENEASDSFDPVFENSYHDDVTFNTEDDDEPPLEPRFKYERLKGEETLPFMKTATFTSIDLHDKFIAIGTATGLIYILDHHGYGNFDSVPPLKPHRCAVSKVKFDETGSYVLSCANDSKIVVSGVGNDKLCCTINIQVMPKSIYFSPDFIRQQSGHCFIMGERNLVLYEKRMFQYKASSLYSGSERDGFIHCCSWNENLIAFTNDTGTRVYERGAERIITSVQPSHDVDRVRSSRSPPKHTWMPENNLVIGWADTVTILKIRDDDGVKKGEVHHIFHVSMFICGISYIPESGIDNMELFLVGLQLEGEDFDDCASVISTVTTLTALESSACTILKTSVIRPLGLKEFELQSEDMIESVKLSNHTLPYMIHGLGIPYLATYFILTTKHIIMAVPYGPEDGIRWRLKYKLYDEALDMAKHNADLLSKTDLSPKKVGRMIIEGYLTGKRARAAASRLPLICGECKEEWEWAVNQFEEVKLCTLLAEVLPDGTPTLDPECYQKVLIACLFNNVKQFRKLVQTWSPDLYMTSFIIDRTQWRIQQISKSGNLADVDETERVLMDALAHLYLYERKYESALKILMSCQDFQIFNVIDKHQLFDLVKDQITELMNINSERALRLLLDNADSVEPSFVMEKIGRQPKLQLAYLTKLMSRNEGTEFADKAVQLYAEYDQKKLLPFLRKNANYNVNKARKLCSDKGYIEETIYLLAKSGNHYDAVKMMVREYRNMEKVIDYCKDQNDPDLWIHLLGVVAEFPAHFSQLIIEASNCLDPLLIMDKLPDDSDIPNLSEALDKLLVDYTNHAELQQCCYDSTLNDLNVLTQGLISAADESVSVNIVSRCSLCAQIIINSNQETTKKFSDIKVFKCGHIFHLACSTSEMERRQSIEEGLCIACSDQIELINV
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as non-selective cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPKYSKHCFSFFPFLLFSYVLIGFTIKLETASSSGLYGTRDSTRLVYNIGVVVDVNSNMGAMANICLSMALSDFYAKHPNYETRLSLQRWESLGAVAAAPAVGYLPQTSAEASFAIQLGDNLSPSYSPLLIRTTMPDFSRLAEATVSTLEMFEWNKVTLIYEDMEFSNAIIPYLTDALVNKDIQLSHKIAIPTFPEDFQILERLEVLMSSQSEVFVVHMSSNLASRLFVSANKEGMMGKGFAWLVTDGLSNFVDTMDPIAIGSMKGVIGLRPYIPKTTALKNFRTRYKRISSMKQNKAATKLNLLGLWLYDIVWGFGMTVERIGNVNSGFLKEMNDRTWLIGTLNPSFRGISGILDLVNRQFQPSVFEIFNITGKRNRVIGYWTNGQGTSKNNNSTSRNTPRILQAEEPTRAKWRIGVPSKKGFTEFVNIQSGNKSNDDELPGFSIEVFRKVWDLALTSTTSYEFVNIDGTYDDLCCQVKYQEIHAAVGDISIVGSRTNCVDFTLPYLETGVAMLIKVRHNGPKDMWIFLKPLSWDLWLVIIAICIFIGIVVRVLERRENTEFNGSARKQLSTILMFPCQSVAIPQRDMVVTNGSRLVLVVWIFLALILMQSYTANLSSILTVNQLQPTIPSIKELRKSYVGYQNHSFVKGFLINQLGFQESMLKPYCSVDDYQEALSKGSENEGVSAIFDEIPYIKLFLAQYTTGYLMVGPTYRTDGLGFALPIGSPMVANFSRAILNFTQGKYMNSLEKKYFGMVSIDQDETGAVSSASPSLTSRSFAGLFIIISIIVLLALLSSKIHILRRLIQRYIFSNSGDIAHPPQINNVEENHNSNQNNRDESIEEGILEGRSS
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Subcellular Localization:
Cell projection, growth cone. Cytoplasm, perinuclear region. Golgi apparatus. Midbody.
Sequence:
MEETNREAVATAVQRVAGMLQRSDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLTQLHNALCDVKDIQNSLADVSKDWRQSINTIENLKDVKDAVVQHSQLASAVENLKNIFSVPEIVRETHDLIEQGELLQAHRKLMDLECSRDDLMYEQYRMDSKNVHDMNLIRGYFGQVQGLSEELSKQLWMVLQRAMVTVRRDPTMLVSVVRIIEREEKIDRRMLDRKKQTGFIPPGRPKCWKNRMNEVLEGTVSGRIESTQSETRESDKMWLVRLLEIMRKYVLDDLTVVKNLMVQCFPPHYNTFQVFFTLYHKAVSARVQELAAEELEANEIVSMLTWDLNTYKSVDMMGHPDLQPECEVKQLEPLLPEKVVNDLLGKYLTTFNSNITGWLRKALETDKKDWQKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQINEIFREKVLGVCLKQMNSFLKRYREEAIVYKEEHLKDRQLPQCYVQYMIAIINNCQTFKESINSLKRKYSQSHEPTQDDATIDKLLNDVAKEGCQFLLDEVFLDLELHLNELLTRKWLTGTHAVDTICVTVEDYFNDFAKIKKPYNQEMTSVAHRRVVFEYLKAIMYKRISFKNADERKEGADRMMKEAEQFKFLFRKLSAGEDTDRLCDSINAIAEVFKLTDPALLYLEVSTLVSKYPDIREEHILALLAIRGDASREMRQTIIETLNQNKPSTSSNFQPVFRDIIVPTISMTSMTSMAVPKLLK
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSSQKRQSTLSRFFTTIKPSQSTESTLTEKVSSKSPPLPPPPPPPTASPSLPSEKLLEFGFDGTKDSTSTRTTTTKSKDVEKRKSTTSSGSSFSSESKPKRPKEKRLTPLEKQILELTEQHQDKILLIQIGYKYKVFGINALKVSKILNIMYISNDIEDTRFHYCSIPDTRLHIHLQRILSHGYKVGVVKQIESTIVKQIEKTSKSSDVMRREVTGVYTKATYLGDESNENTKGSWDGLSSSSSSSSSDVPEYIVCINEVSEKQFAIVAVQPLIGEVIFDSFKDDISRQELETRLLYLRPVEVIVITNGSSEQISGPTLMTLKLINHNCNIIHKSGSPSENGNENENENENEAIEAIMSKYLNEKLVEYYSINFSIPIQQCFEYLLLYLNEFKLTNIFTIPENITNFQDSKKYMILPANTLNSLEIFTNTTDHTTKGSLFKLLNNTKTIFGSRLLQKWVSRPLVHIQDIKDRHQAIEDLQSEYNHVVDSISNFLTKIKYLDLEGLLSKIHYSSTNNNNNNLRINRKQVYLLLSNLQEILILVQKFEKSIKSFKFKSSLLIQIFDELLTISQTDIIIIENFLSMIDLSFIDCKESSEQCRKFFKRNSFDSIELQYQNIAQYQQQIEQEQLEIIRKELGNSKLKYVQKDGERYLIEIRNNQRDKLSKILDDKDYILIKSTQTITRYRKKSVTEYLKLLQYHEEMLIKTCDEEFQNFLKDLDSNYTLFYKIIKNLAIFDCLLSLTTTSSLPNYTRPTLIDDDLTILVKQARHPTIEQLRPNYVANDININIEYDKNRVLIITGPNMGGKSSYVKTVALLTVMTQIGCYLPCQNATMGIFDSIFIRMGANDNILKGYSTFMMEMLQCKNIISMMSNRSLIILDEIGRGTGTIDGISLAYSILKYLIESEFKPLVLFITHYPSIHVLEQEYPNQLVVNYHMGYQEIKNNTPGEIPEIIFLYNLCRGVVNNSYGLNVAKLAGISHDIIKQAYRVSEKVKSDIELKEYWKFAHSLNKALKEGGSSSPNQLDDIDYYILSKHSSL
The following text describes a protein:
Function:
Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function.
Subcellular Localization:
Endoplasmic reticulum. Golgi apparatus. Secreted.
Sequence:
MCPLLVLTGLPPYRIWWPLILHLILVIWESPNAESSPVFSSKQEANHVLKVRKRAFNFMEELKPGSLERECIEETCNFEEAYEIFENNEDTLKFWTTYVDGDQCQSNPCINAECKDGIGRFDCICNEGWEGRLCGYEVVYSNCSLNNGGCTHFCTEAVNSTRRVCSCATGYMLHDDQNTCQPAVEFPCGKLKIVDYEFSARLTGAKPGRKGDAPWQAMLRYEKKLKCGGVLIHPSWVLTAAHCVQHAGKYTVRLGEYDIRKLEDTEQQFAVAKIISHPAYQRDTSDNDIALVRLVQPVVYNKYILPICLPSLDLAESKLMVNDTKVVVTGWGREDEKALNFSSVLKYIEIPIASLNECAETLNDGVSDNMLCAGQLGHIQDACYGDSGGPMVTPFGGSWFLVGLVSWGEGCGRINNFGVYTKVSRYLDWVTQKMAEYEEARRLAEVSKIEKQNAKKSWKVRP
The following text describes a protein:
Function:
Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MWPFSSSTSAEPGASADRCPVDEETRQAWLKANPGKAHPFQPDAALSPQAGASHTSSYRTNDESRLSSDREISSIPRSYSPLANPTAAQTAQAPQARSTPAPDAEDSDGKWVYPSAKQFYNAMKRKNQNPQVADMDVVVPIHNAVNEQAWKQILAWERMWTGRAEGNEETKLVSFKGRPRELTWRAWFNGLAGYQHPFDRHDWTVERPGGEQVRYIIDFYTGRAQAAAAATASIGEHFSAAAQQRTGLSFYLDVRPAPSTLQGLAMRSTRSWHKYFGSPDSAPH
The following text describes a protein:
Function:
May be involved in protection from oxidative damage.
Subcellular Localization:
Mitochondrion.
Sequence:
MSFLFRRSIEQPRVNEKETNKEVKDEPQHQQQEKEDDNSKQEELLSDSVNEKPKEQPKPVKRRGTFFGNLLGNGSKNSSSASLNSSHSSVSSSSKFPPLGPLTLTGYKESTHHRLLDSELANNIRNLIPARFQLFDNWELVYSLEQHGISLNTLYRNSNPEHQLRLLKKQKAAEKGFADSIVKNMVVGDTSRPRYSFEPKRSQSYVLVIKDNHNNKFGAYLSENLKPMEHRRYYGNGECFLWKCEKYDPSKLDHAVDKRATQEIRFKAFMYTGINDNIIYSNHDFIAIGSSNGQNGLFIDKSLLSGVSYSCDTFGNEILNSSPQNAKFGSFKIKGLEVWRIGTLE
The following text describes a protein:
Function:
Transcription factor. Interacts, when in complex with WRKY71, specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Represses specifically gibberellic acid (GA)-induced promoters in aleurone cells, probably by interfering with GAM1.
Subcellular Localization:
Nucleus.
Sequence:
MMTMDLMGGYGRADEQAAIQEAAAAGLRGMEHLILRLSQTGTGAESSPAVAAPEQAKGKQQQQQEQVDCREITDMTVSKFKKVISILNRTGHARFRRGPVVAQSQGPEHQQQAPVVVRSSSVTLDFTKAGYGNKDAGLSVSAATASSSFLSSVTGDGSVSNGRAGVSSSMVFPPPPSASCGKPPLAAKHKCHDHAHSENVAGASGGRCHCSKRRKSRVRRMTRVPAISSKAAEIPADDFSWRKYGQKPIKGSPYPRGYYKCSTVRGCPARKHVERDPSEPSMLIVTYEGDHRHAPADQEPPPPPLAALHEL