lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSARKLQQEFDKLNKKISEGLQAFDEIKDKINATESASQREKLENDLKKELKKLQRSRDQLKQWLGDSSIKLDKNVLQENRTKIEHAMDQFKELEKSSKIKQFSNEGLELQSQQKRSRFGDDAKYQEACTYINEVIEQLNGQNEELEQELDSLSGQSKRKGGSSIQSSIDDVKYKIERNNSHISKLEEVLENLDNDKLDPARIDDIKDDLDYYVENNQDEDYVEYDEFYDQLEVDEEDDVEVQGSLAQMAAETEDERRRDEERKREEKEKEKQQQNPPRTSSSVSSSSSSNQNNIGNNTPPATQIKPSVVTVAAIGDQNNNSASSASSTSTPVKKLKPTLAPAPAPPPITSATSYSNAIKAAQTASTSSTSNSSIAHTANDNNNTNKGNRSVSPLASTDNHTHAPAAVSTPVKVLPPGLNHDTSMNSTLRSESSSPLVGHAKVNNNHELQISRSQSPMVSNENKVFSDTISRIVNVAHSRLNDPLPLQSITGLLETSLLNCPDSYDAEKPRQYNPVNVHPSSIDYPQEPMYELNSSHYMKKFDNDTLFFCFYYGDGIDSISKYNAAKELSRRGWVFNTEFSQWFSKDSKNGGKNRSMSVIQREEENGNIIGDNSNGNEELREKIDDNGGIPSNYKYFDYEKTWLTRRRENYQFATENRQIFQ
The following text describes a protein:
Function:
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLYSLLYGYFNINLFQYLTFRAGLGFFIAFFLTLFLMPKFILWAKAKKANQPISSFVPSHQNKKDTPTMGGIVFVFATIVASVLCASLGNLYVLLGLIVLVGFSFVGFRDDYTKINQQSNAGMSAKMKFGMLFILSLIVSVLLSLKGLDTFLYAPFLKNPLFEMPTMLAVGFWVLVFLSTSNAVNLTDGLDGLASVPSIFTLLSLSIFVYVAGNAEFSKYLLYPKVIDVGELFVVSLALVGSLFGFLWYNCNPASVFMGDSGSLALGGFIAYNAIVSHNEILLVLMGSIFVIETLSVILQVGSYKTRKKRLFLMAPIHHHFEQKGWAENKVIVRFWIISMLSNLVALLSLKVR
The following text describes a protein:
Function:
Inhibitor of the cyclin-dependent kinase CDC28. Necessary for cell cycle arrest. Involved in pheromone response. Contributes to mating efficiency. Required for oriented polarization of yeast cells in response to mating pheromones.
Miscellaneous:
MISCELLANEOUS: Present with 238 molecules/cell in log phase SD medium.
Domain:
There is evidence to suggest that the N-terminal part may be sufficient for cell cycle arrest and the C-terminal may be necessary for some step in mating.
Sequence:
MKTPTRVSFEKKIHTPPSGDRDAERSPPKKFLRGLSGKVFRKTPEFKKQQMPTFGYIEESQFTPNLGLMMSKRGNIPKPLNLSKPISPPPSLKKTAGSVASGFSKTGQLSALQSPVNITSSNKYNIKATNLTTSLLRESISDSTTMCDTLSDINLTVMDEDYRIDGDSYYEEDSPTFMISLERNIKKCNSQFSPKRYIGEKCLICEESISSTFTGEKVVESTCSHTSHYNCYLMLFETLYFQGKFPECKICGEVSKPKDKDIVPEMVSKLLTGAGAHDDGPSSNMQQQWIDLKTARSFTGEFPQFTPQEQLIRTADISCDGFRTPRLSNSNQFEAVSYLDSPFLNSPFVNKMATTDPFDLSDDEKLDCDDEIDESAAEVWFSKTGGEHVMVSVKFQEMRTSDDLGVLQDVNHVDHEELEEREKEWKKKIDQYIETNVDKDSEFGSLILFDKLMYSDDGEQWVDNNLVILFSKFLVLFDFEEMKILGKIPRDQFYQVIKFNEDVLLCSLKSTNIPEIYLRFNENCEKWLLPKWKYCLENSSLETLPLSEIVSTVKELSHVNIIGALGAPPDVISAQSHDSRLPWKRLHSDTPLKLIVCLNLSHADGELYRKRVLKSVHQILDGLNTDDLLGIVVVGRDGSGVVGPFGTFIGMINKNWDGWTTFLDNLEVVNPNVFRDEKQQYKVTLQTCERLASTSAYVDTDDHIATGYAKQILVLNGSDVVDIEHDQKLKKAFDQLSYHWRYEISQRRMTPLNASIKQFLEELHTKRYLDVTLRLPQATFEQVYLGDMAAGEQKTRLIMDEHPHSSLIEIEYFDLVKQQRIHQTLEVPNL
The following text describes a protein:
Function:
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
Sequence:
MLQLCSTFRPQLLFSPQIRFTDGVLIPRLNFGSSNSVVSFRPVIRCQRVSGGRGGANRSKPAKPPVKEGSNKTVIEGLVTESLPNGMFRVDLENGDNILGYICGKIRKNFIRILPGDKVKVEMSVYDSTKGRIVFRMSSRD
The following text describes a protein:
Function:
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.
Sequence:
MKKEQIIQGPCTIKVLEGEARILGIEIQKNDLLTIPSDKTYTLVYDENTRLETDCKKLLDNLNLRWDEIVEEIINTVGVVLLLGNVDSGKTYLTNLFTNLATSYLKIIDADVGQSTLFLPTFIAELKPMRKTLNLEELGYDTLEFFGDITPSTNPRLHVQKILRLYETTPKERLTVIDTDGWTVGLNSMLHKFELIYTIDPDYIIVFDQKIKDSLPENYRNKAILLKSVNLHKSRSERKANRIAKYERYFKEAKNIKTLSENLLGKQISNILYCAWGEYIQLSDEEPCTDYYIPLNLLKGALLGIIENKKVIGAALLDDLKENEITILSRVNKFTGLVLGYISLNDKFEERRIRFRKCKS
The following text describes a protein:
Function:
Catalyzes the formation of (E)-feruloyl-CoA, AMP and diphosphate from (E)-ferulate, CoA and ATP. Involved in the degradation pathway of lignin-derived aromatic compounds of plant cell walls. Catalyzes the first enzymatic step in the conversion of ferulic acid into high value compound vanillin.
Sequence:
MRNQGLGSWPVRRARMSPHATAVRHGGTALTYAELSRRVARLANGLRAAGVRPGDRVAYLGPNHPAYLETLFACGQAGAVFVPLNFRLGVPELDHALADSGASVLIHTPEHAETVAALAAGRLLRVPAGELDAADDEPPDLPVGLDDVCLLMYTSGSTGRPKGAMLTHGNLTWNCVNVLVETDLASDERALVAAPLFHAAALGMVCLPTLLKGGTVILHSAFDPGAVLSAVEQERVTLVFGVPTMYQAIAAHPRWRSADLSSLRTLLCGGAPVPADLASRYLDRGLAFVQGYGMTEAAPGVLVLDRAHVAEKIGSAGVPSFFTDVRLAGPSGEPVPPGEKGEIVVSGPNVMKGYWGRPEATAEVLRDGWFHSGDVATVDGDGYFHVVDRLKDMIISGGENIYPAEVENELYGYPGVEACAVIGVPDPRWGEVGKAVVVPADGSRIDGDELLAWLRTRLAGYKVPKSVEFTDRLPTTGSGKILKGEVRRRFG
The following text describes a protein:
Function:
Inhibits trypsin.
Subcellular Localization:
Secreted.
Sequence:
MKPAGAFLLLISLACLFLSVDAVSQGGFQAFCSNYEKTLAPDGKSCPKTHKPVCGTDGKTYQNRCAFCQTAMERSLGKLGFKHEGKC
The following text describes a protein:
Function:
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
Sequence:
MPVRQLPEQVVNRIAAGEVVERPASVVKELVENAIDAGASRIDVFTDGGGRRRIGITDDGSGMTAKDLALAVERHATSKLDDEDLLQIRTLGFRGEALPSIGSVARLSITTRHAGEPHAWALTVEGGEKSEIMPAALAHGTRVEVNDLFYATPARLKFLKTDRTEAEAIREVVRRLAMARPDVAFTLAGEERAPVTWAAALPGAAGRLTRLGDILGAEFRSHAIEVHAEREGIVVSGYAAAPALTKANALGQYLFVNGRPVRDKLILGAVRAAYSDYLPRDRHPVLALFVTLDPREVDANVHPAKTEVRFRNAGLVRALIVHGLKEALAREGRRTAANSGESALSSFRPAFTPRPASWDWRASPSAPVAPMPSFDGAAAPAFTERAQAAFDVGAPSADVRFETQPVSDLVDRPLGAARTQIHETYIVSQTRDGLIIVDQHAAHERIVYEGLKASLAANGVQRQILLIPEIVEMDEATVERLLERSDELASFGLAIESFGPGAVAVRETPSLLGKTNAGGLLRDLSEHMAEWDEALPLERRLMHVAATMACHGSVRAGRRLRPEEMNALLREMEETPNSGQCNHGRPTYVELKLSDVEKLFGRR
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere. Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MQETWRPLETEALAQQNLSTRAELEAWVEAQKTRILEEKRADQLQAQEHAHESDDAQRRRETLQVEYQKLSTDTHAKERELNASQVEIEVLQAEKRKREPVVKELVERTVQEDARLKQLLADTQKQRTAQEQQLQELKQGLATYERLGLHFEHAEVDDCNENVASLNELVTDLNESGDLALFIRSMRRQFKQLV
The following text describes a protein:
Function:
Type VI secretion exported toxin that acts as a glycohydrolase on bacterial target cells and degrades the essential dinucleotides NAD(+) and NADP(+), thereby inducing bacteriostasis. The activity resides in the C-terminal region that is initially neutralized by the cognate immunity protein Tsi6.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDAQAAARLGDEIAHGFGVAAMVAGAVAGALIGAAVVAATAATGGLAAVILAGSIAAGGLSMFQIVKGLTTIFELPEPTTGVLIRGSFNVYVNSRNAMRAGDDVSATCSGLPLNHPLWPFPVLIAEGSATVYINGKPAARLQSKMVCGAHIKTGSQNTFIGGPTERVAFVLDLEEWLHTGLEALGLAALAGGLLLAAMAGVAALVGVVAIGGLMMGGMALLGDLGDRLGPGYRDLFQGVAGMALLGFGPKLAGRRPAAVTSETAQRRAYLNNKFGRSGNLDHDINYRGNRETAAKFFKSKDIDPADAESYMNGLDFNHPVRVETLAPGKNLWQYQSPGAPQGNWYTLSPRVQPTELGINPMGTNRAANTIEPKVLNSYRTTQKVEVLRSTAAPTDDFWSVKGQSYPAKGGAQQLFSNEKGSFGLLPREGS
The following text describes a protein:
Function:
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.
Subcellular Localization:
Nucleus.
Sequence:
MGDNFGIHRGQGKKVSEMVEDRTQGQVLSDFMMQLEDYTPTIPDAVTSFYLNSAGFEGADPRIVRLISIAAQKFVSDVANDALQHCKTRTNSAPSSGHGSSKNQNQKSSKDRKYTLTMEDLQPALNDYGITVRKAHYFV
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MSLEEFNANKSPVKDFYHGKTVLLTGGSGFLGKLFIEKLIKCGVREILLLLRSKKGVSPEERLHALLKKEAVFINYQQQPELYLDRLKVIEGDISRPGLAISNDDLDYVIKHTNIVLHSAADVRFDESMKESVETNVRGTDHLLNIAEKCANLEVFVYVSSAFSQCIKESVEEKFYTPNIDPLELIKMMENEPRLDELEAVSKKMVEPWPNTYSFTKALAEEVVRRRRDKMPIAIVRPSIVTSTYADPIVGWTDNFYGFNGVVSGAGTGVLRIFHIRDEYKADIIPADIVINGTLVAAHYAAKHPAEENVFNCTMDENHTTWGDIRNDCLSQKGVVAVKKSLWIPTYNTTRYYYVASFLQVFYHLLPAVFFDLVLRCRGEKPQILRLYRKVHRFSDVLRFFTNHQFQFATKRMRQVVDGMEIVDRHLFPCDMKSVVWSKFGVNHIRGCRVYLLGEPWDTNEEALQIYRRRRLIHLLMLGVIYSMYVVVGLRLLEAAGVPDLRSFLGCTQFA
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2.
Subcellular Localization:
Cytoplasm.
Sequence:
MLSEFGPSPMLGNNENSFGDEFEKEIGMLLREQRRQEADDHEKELNLYRSGSAPPTIEGSLSAVGGLFNNNGFRSEEELRSDPAYLSYYYANVNLNPRLPPPLLSKEDWRFAQRMQGGSSAIGDRRKVNKNDNGSSSGRSLFAMPPGFNSIKAENENESDKLQGSVEWGGDGLIGLPGLGLGSKQKSIAEIFQDDLSRATPAPGPPSRPASRNAFDESSDNLGSAEAELSHLRHEFSTSDPLRSVSNGQGSSAAQHVGAPASFTYAAALGASLSRSTTPDAQRIARAPSPSLTPIGGGRVATSEKRSVNSPNSFNGVSHTAESADLLAALSSMNLSNGSQNNSQQHAYLKRSESAQFNMSSKSHSAKGPYIDTGAGNNGRSDLNSSNLHDDLHRSAVASNNSYVKGSQTSTLNGGGGVLSQYQHMDSPSNYGLGSHSVNPVTSHLGNYNLPPLFETAAAASGMALPGMDSRMLGASHLNSGVSEQNLSRMGNQMSGSALQASFMDPMYLQYLTAEYVAQVAALNDPSMDRNYMANSYMDLLQKAYLGNALSPKSQYGVPLSSKGSGSSHHGYYGNPAFGVGLSYPGSPLASPVVPNSPVGPGSPMRHGDYNMRFPGAMRNVTSGVIGPWHLDNMENSFASSLLEEFKSNKTRCFELSEIAGHVVEFSADQYGSRFIQQKLETATPEEKNMVFQEIIPQALTLMTDVFGNYVIQKFFEHGMASQRRELASKLFSHVLTLSLQMYGCRVIQKAIEVVDVDQKIKMVEELDGHVMRCVRDQNGNHVVQKCIECVPEEHIQFIVSTFFGQVVNLSTHPYGCRVIQRVLEHCCDAITQSKVMEEILGSVSMLAQDQYGNYVIQHVLEHGKPHERSAIIKELAGKIVQMSQQKFASNVVEKCLAFGGASERQLLVDEMLGTTDENEPLQAMMKDQFANYVVQKVLETCSDQQRELILSRIKVHLNALKKYTYGKHIVARVEKLVAAGERRIAAQSPNLA
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEAVIREGALRLLTSEASCDVILSCQGHRLMAHKLILSIASPMLHDLLLQDMTEPSVLIFPDINSNTMSLILDYIYTGSVIIYSNTINDFLTAANLLKLHIDVEFLQKANTLREYKLFEKKEEKPANDVFSKRNQRKLPSLVPISSFMPSKKERKLVSCVIPSPWMPREMPVLSDPRTCLSSTERANVHQIRDRLEESDPNNNNSQQHQKNKTNSILSPSSNSSSELDLSTSLNKLAFEQKLVPQLNDSLVVNKENDKCVNDSTTAFTCPKKHTNRTLCSRKEEGTEEKNSCHDNEKQKPFKCEDCKKTFSQLRNYKYHRSVHEGTKEFAAKCPECGKNFNDRGYLSSHMKIHRDRKEYACPHCPKRFNQRVAYNMHLRIHTGIKPHECPTCGKSFSRKMLLKQHQRVHTGERPYSCPECGKTFADRSNMSLHARLHTGVKPYSCNLCSKSFTKKHHLKTHMNFHTGLKPYTCQKCGLAFSQSSNMRTHYKKCVLKSNGGPSSAEADSN
The following text describes a protein:
Function:
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices bZIP60 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator which then induces transcription of UPR target genes. Involved in organ growth regulation. Plays a role in plant immunity and abiotic stress responses.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MPPRCPFLRHLFFLLLLLSPWIMSPCGGAADDVTYPIVPSSPGRRSILQIRREPPTEPNTKLVVDRDGKVFLKQQPKETPYWSFSTGSPMHSLYQAPANNNTENATEITRPHIIVEYLNNSKAATTVDGYHNWTVQEFFRQKPLVTDDGVTLGSETTSAYLVDGRSGRLIHVYKSTGDTKITNALVKPASTEDFVNEPLLIRRTDSKLEHFSKTTGKLVWNLTVSHFRAALLCDPVFNSGYDLGPKLQTGIYMPLLCGSQIDVRGPEIVIRVLHDQPMNVKMLPSPSLNHFESENSIMPFGKARESRKLQEQHKQKYTYLFGQWSPVKLLAPLVLLGVVVSVFIKKFSSRGSDVSLKAGPSKKKKNRKSAKDTNRQSVPRGQDQFELIEGGQMLLGFNNFQSGATDGRKIGKLFLSSKEIAKGSNGTVVFEGIYEGRPVAVKRLVRSHHEVAFKEIQNLIASDQHTNIIRWYGVEYDQDFVYLSLERCTCSLDDLIKSYLEFSMTKVLENNDSTEGVAAYKIQLDSLEGVIKGNNFWKVGGHPSPLMLKLMRDIVCGIVHLHELGIVHRDLKPQNVLISKDMTLSAKLSDMGISKRMSRDMSSLGHLATGSGSSGWQAPEQLLQGRQTRAVDMFSLGCVIFYTITGCKHPFGDDLERDVNIVKNKVDLFLVEHVPEASDLISRLLNPDPDLRPSATEVLLHPMFWNSEMRLSFLRDASDRVELENREADSEILKAMESTAPVAIGGKWDEKLEPVFITNIGRYRRYKYDSIRDLLRVIRNKLNHHRELPPEIQELVGTVPEGFDEYFAVRFPKLLIEVYRVISLHCREEEVFRKYFKCDII
The following text describes a protein:
Function:
May play a role in cardiac physiology.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGNYKSRPTQTCTDEWKKKVSESYVIVIERLEDDLQLKEKELTELRHIFGSDDAFSKVNLNYRTENGLSLLHLCCICGGNKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDSAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFFDIAKLLVEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVANIYGDTPLHLACYNGKFEVAKEIIQISGIESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVISINHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKEEQTCLMWAYEKGHDAIVTLLKHYKRPQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADVLLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCRLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWELLTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLMRGWNACPEGRPEFSEVVTKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVSRGGPGRSHVAALRNRFELEYALNARSYAAWSQSAGQCPSQGLSLEDMKRSLPFSPIDKYGYVSDPMSPMYFHSCRNSGSFEDSS
The following text describes a protein:
Function:
Acts as a CAK-activating kinase that specifically activates crk1 of the crk1-mcs2 CAK complex.
Sequence:
MKSVGHFVPWLTDIRHLTDGTISEVFVGERKNSKKLYVIKVQGLVFKRPPHDAMRGKLILESIGHPHIERIVDSFIDNEAGSVYLITSFKSFVLSDVMDEISIDTKCKIVLQISSALEYLEKHGILHRDIHPNNILLDSMNGPAYLSDFSIAWSKQHPGEEVQELIPQIGTGHYRAIETLFGCHSYGHEVDRWTFGILIAELFSNQALFDDGSSEGWPSELRLTSSIIQTLGTPNPSMWPELSTFPDWNKFIFHEYPPKPWSEILPSVDTSIQYIVSHLVTYSNRASPSFVIESFPKVSARLSQYA
The following text describes a protein:
Function:
Acts as an inhibitor of bacterial RNA polymerase by interacting with RpoC subunit and thus preventing promoter recognition by RpoE. Non-DNA-binding transcription factor that plays a role in the transcriptional switch that abolishes transcription of the viral early genes (class I) by the host RNA polymerase but allows transcription of late genes (class II and class III) by T7 RNA polymerase.
Sequence:
MSNVNTGSLSVDNKKFWATVESSEHSFEVPIYAETLDEALELAEWQYVPAGFEVTRVRPCVAPK
The following text describes a protein:
Function:
May function as sodium-coupled metabolite transporter across the chloroplast envelope.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Plastid, chloroplast envelope.
Sequence:
MKNNCGLYVANDINYLIGIIFQSFLLLSISNLLHFPLRRLGQPSAVSQMLAGILLGRSGIASSPYIGTVVFPDGNMDYLSSMASLGRMFYMFFLGLELNVPYILRIKRSSTIVAVGGIFMCLIVGGVISPVIYWMTRAYGDRFLFAVTVMLVFTDTASPILVRMVSELKLATSDFGRLATAVALINDILCLFLVALLAQTTTREFSVGEKIGVGIATLLILGSSAYLARIGVRWLNRKNRQRKHIKNSEVVSIVLFIVGVSSLIELMGYNSMLSSFFLGLAIPREGCTARTLVHRLIYPVQNILLPIYIGYAGVQTSFFVMNSLRFTLSVVAVVVLSTVAKVGGTVAATQYLGMPLQDGLLLGFLLNVKGHIDIIVLGLSSKHHILGADALMVFLVTVAMSTLMVGPVVAAVARREKKQRKLKPSGIEHQSAETELVFLACVHSPRDAPSVLNLIEISTGPDRAPVTVYMMQLVELQKKTKTDLLYHQQEDDGQYSDDEDYGGRNHARRINVTVDAFMVDTGIRVWQLKIVSLLDGMDVRTCRMAKDVRASIVIVPFHRFQRVDGKMVGGRDWIKDVNQQIPANVPCTLGILVDRGLSEMTQITNTQEGFHVAVLFFGGEDDREAAAFGGRLALHPSVSLTLFKFVLSEARRSVIKMQASKKADAYEILVEITEKENESYRDDAFLKSFYNRFIQTGKAKYEEKIMDDGKDTADCIAAMGKFYSLFLVGKDSRSPLLENPLNDYGDDCPNLGHVGNLLASTCFTTTASALVLQKHKKKPPAKKEETAGKIDDVTHQQNQQEE
The following text describes a protein:
Function:
Bifunctional aspartate kinase and homoserine dehydrogenase that catalyzes the first and the third steps toward the synthesis of lysine, methionine and threonine from aspartate.
Sequence:
MRLDVSFLLIATGLSSVTSFAPSRSSSSSSSSSTITTSSSWLPKSPAFTATTRDHPSTTTTLLHYTATATTNIDICPQSITRPNSNPNPWEVHKFGGASLADAELYRTVGDLLLRESSGRVLQAISARAGMTDQLVAVVSSALQDITQAETELSKALEGQLSILKELAPPSITTEIEERMKKDAQDILSVVQSLRMIRSVPPSVMEVVTGFGEIWSAQTLYAYLKNKGVKCAWLDARDVLIVKSENANAGLGEKGSSSIGTLDEAPIVIATGFVATSSEGVPTTLKRSGSDYSATIFAKLCSAARVTMWKNTDGVYTADPRRVPEAFSIASLKYDEAMELAYFGAQVLHPSAMVPCIDGNIPVYVRNIFNPSFAGTVIQGRCASLSEVNKDGKVVNWRSKKGEIPIKGITSVDRVSLLTLEGASVIGGAEVAERFMGSMADAGIDVLMVTQASSESSITVVVPENQGKKALGALQSTFELELSRSNVNSISLTDVPMAIVAIVGEGMAMNSGVSASFMSALAKANVNIRVIAQGSSERQVAVVVEGKDVSRALRSAHMAFTLSQTMLSVVILGGTGKLGSALIRQLNAQRDSLAKNLNFGVCVNAIASSSKMILGKNGACLATSRAGDMLEADDAQDLDMEALTAALEADVNPHRVIIDCTNSESVADHYEEWMSKGVNVISPGRKAGAGSLERYNAIREAQRANAVEWQYESSVGSALPILTTLRDLMQTGDEVQMLRGCLSGTMAYIFHTMDEKTSFSEAVRQAVEQDFTENDIKEDLAGYDAALKIVILARELGLNISVEDVEVESLLPEELRNKEYTGTKEEVNAAILEDLKSLDEPMMERWKEAKSDDRLLRYKFVIDVPNGKCKCSLEAVDNSDTLYRLRNNENLVAFETSRYTTSPLIVKGAAAGPELSAAGMFADLLRLGRAFSTFQT
The following text describes a protein:
Function:
Involved in the recovery of exogenous heme iron (By similarity). Extracts iron from heme while preserving the protoporphyrin ring intact (By similarity). Part of the iron transporter system efeUOB/M involved in iron import. Catalyzes the peroxide-mediated oxidation of Fe(2+) into Fe(3+); EfeM binds Fe(3+) and delivers it to the cell membrane permease EfeU.
Subcellular Localization:
Secreted. Cell membrane; Peripheral membrane protein; Extracellular side.
Sequence:
MSDEQKKPEQIHRRDILKWGAMAGAAVAIGASGLGGLAPLVQTAAKPSKKDEKEEEQIVPFYGKHQAGITTAHQTYVYFAALDVTAKDKSDIITLFRNWTSLTQMLTSGKKMSAEQRNQYLPPQDTGESADLSPSNLTVTFGFGPGFFEKDGKDRFGLKSKKPKHLAALPAMPNDNLDEKQGGGDICIQVCADDEQVAFHALRNLLNQAVGTCEVRFVNKGFLSGGKNGETPRNLFGFKDGTGNQSTKDDTLMNSIVWIQSGEPDWMTGGTYMAFRKIKMFLEVWDRSSLKDQEDTFGRRKSSGAPFGQKKETDPVKLNQIPSNSHVSLAKSTGKQILRRAFSYTEGLDPKTGYMDAGLLFISFQKNPDNQFIPMLKALSAKDALNEYTQTIGSALYACPGGCKKGEYIAQRLLES
The following text describes a protein:
Function:
Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MKQPTLIRPRLRHRRSTPAAATKMCPKRHWLVNNRAAGSRGSGGAAARSRRSLDQIVEVLVALIVVNCLATAAAALITPPDSLESLGSLGIPSSSASSSEDDDDMSSGFYRIPHRLEGYPQLQQLQRGQNFKISPKPCSFGRVEGTCMFVWECIKSEGKHVGMCVDSFMFGSCCTHNYTDNIVLPQTAFSYTRPTKPLTLRPRPPAAPYKPMISGMTTIERPHGAGTLVIRPSGPHHQGTLARPHPPPYQSKPTTASDLHGSASHPSSSSSSSSSSNPNSIWHTSTQQQQQQQHQQNQQNHWQMTTEPSFITKPRPTGWTKPGIVNLPMPARPSKPSKPTKKPIVYDRTPPPPPSVPPSTSTSTTSTSLIWPAQTHPPQPHRPTRPQLSPGTSLAASSSSHWPSSTTSTTSSTTSTTTTTTTTRRTTTPTTTTRRTTTNKPTRPYQRPTTATSSSSTSTTSSKTPTTTRPISSSSSSSSGIVTSSQRPTQPTHRTPVLATSGIETNEISDSSIPDAGALGHVKTISAARSECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLLISQIRIRVGEYDFSHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLPETDSLLIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWILEHVR
The following text describes a protein:
Function:
Involved in DNA recombination.
Sequence:
MDITLMISAVVALAAGAVIGWLATKAHADQIRADLIEERRELDIELSAARQQLAQEAHWRSECELLNNELRSLHSINTSLEADLREVTTRLEATQQHAEDKIRQMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLTPLREQLDGFRRQVQESFGKEAQERHTLAHEIRNLQQLNAQMAQEAINLTRALKGDNKAQGNWGEVVLARVLEASGLREGYEYETQVSIENDARSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTREAALQEHIASVRNHIRLLGRKDYQQLPGLRSLDYVLMFIPVEPAFLLALDKQPELITEALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQHIADRASKLYDKMRLFVDDMSAIGQSLDKAQDNYRQAMKKLASGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVTQDEEYRLRSIPEGRQDEHYPNDERVKQQLS
The following text describes a protein:
Function:
Displays kinase activity. Inhibits neuromuscular junction (NMJ) growth by interacting with and promoting the proteasome-mediated degradation of the receptor tkv which inhibits bone morphogenetic protein (BMP) signaling.
Subcellular Localization:
Cytoplasm.
Sequence:
MGNSQPRNASRSRRTSQWPQGAAELGASASDHHYHQEELYQEQQQQQQQPQQEQPSSRRIQFQAHTNQPTQSHPPGDEEQPVQSQQQQLSTWSLGSLSGGRLNWSFSGARNSFRHRNKATRKSLTSLHGSRRGKTQWHRPLTNSIFNSHFKETSKNDLYRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCGHHPFIVKQIDLWQNRHNLHILSEYVPNGELFSKITHFSIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLGANTRTMCGTFKYMAPEILCGEPYGHAVDWWALGVIACQMLTQKSPNIKRHLLRRRESVEPEDGLSNAPSIAQINGCLQDSDGDSEDFLPEEVQHLTHEGRDVLRKLLTIEPRQRIRSVMALQRIAIYKDYNLSSKQLLSLSPREIIARDGIRIYEDRHFDQLTNQCAIDAFLDF
The following text describes a protein:
Function:
Probable E3 ubiquitin-protein ligase that may regulate the response to iron deficiency and thus contributes to iron homeostasis.
Subcellular Localization:
Membrane; Single-pass membrane protein. Nucleus.
Sequence:
MGVGVPLPPDKNRRENKPPDIGSSSSAVSVVNARLSDSPILLFVYFHKAFRAQLAELHRLAGDRVKTGSYLAVELRRKFDYLKLVYKYHSAAEDEVIFSALDTRVKNIAFNYSLEHDSTEDLFTSIFHWLHVLEEERGDTADVLREVILCIGTIQSSICHHMLKEERQVFPLLIENFSSEEQASLVWQFMCSVPVMVLEEIFPWMTSLLSPMERSEVENCVKQVVPKELSLQLVINSWLIDDDSQSSSFAALTKIMKEVHSENMNNSSHQADSSNGLFQRFWQWSKTSFSSPNTEHTLLLGIQLLHNAIKRDLLDIQKGLSQLKFPSLSLELNVLMVRLNFLADVLIFYGNAFKKFFYPVFEEMVGQHTSASKQFNIDGHVENFKRWLDLETRTGSDKFVITLQDKVKSLMLIVSQQFSLEEAEVFSIISKNCNIEMQRQLLYMSLHVLPLGLLKCVIMWFSAQLSEDESQSIIHFLSLEDSFPNKPFAHLLLQWFRFGYSGKTSVESFWDELSFMFKPRCPSEEEHTEEASGSIYNGSDPSLLGNKSKSSTWFQPVDLPPGYMNETPYSSAMNHQMLIPGNLKPLQQLPGDNIGDCLTMDWKPIDLLFLFHKAMQKDIDYLVRGSARLASDSSFLGEFHQRFHLIKFLYQIHSDAEDEIAFPALEAKGQLQNISQSYSIDHELELGRLNKVSFLLNEMAELNMLLLSINSNVVEKYENLCLSLQDICKSIHKLLSEHLHREETELWSLFRDCFTIEEQEKIIASMLGRISGEILQDMIPWLMESLIPEEQQAVMSLWRQATRKTMFAEWLKEWYNSNKVCTRVDEKMYKEETLGYQMRRTSSQSDQANKYECLLSMSQEDVEATVRRISRDSSLDPQKKSYIMQNFLMSRWIATQRIRNLEPSVISNNMEVVPGQHPSYRDPQKGIFGCKHYKRNCKLLAPCCNKLFTCIRCHDEEVDHSVDRKQITTMMCMKCMIIQPIGASCSNSSCNFSMGKYYCKICKLFDDEREIYHCPYCNLCRVGKGLGIEYFHCMKCNACMSRTLVEHVCREKCLEDNCPICHEYIFTSNSPAKALPCGHVMHSACFQEYTCSHYTCPICSKSLGDMKVYFRMLDALLAEQKMPDEYLNQTQVILCNDCGRKGNAPYHWLYHKCSCCASYNTRLL
The following text describes a protein:
Function:
Positive regulator of the glv operon expression, which consists of GlvA, GlvR and GlvC.
Sequence:
MQLEELINQHYSKLNDNDFHILKYILNHKHTCYHLGIDALAKACSVSRSSILRLAQKLGFSGYSEFRVFLKWEDQPEEGESMSFEKLLDDIEANLKFLRTKDMTDMCQLIDAADRIFVYGSGNAQKICARDLQRMFIPRHRYLILIEDTNEFNLMRDDFKVNDLFIIISLSGETPELIPQARMLSAKGIPFISITNLKNNVLAQLTPHNLYATSKPVTLSDRTEIVAFAPFFLVGEALFRAYVDYKEAEKNDNE
The following text describes a protein:
Function:
Activates transcription of the denitrifying genes (nitrate reductase narA and nitrite reductase nirK) under anaerobic conditions.
Sequence:
MNEGVHGEIHVADPSICRVSEASKETAVESVSRSVGATGDTAAVEFTAPSSAAIDDADEIFHHEQKTIYRVTHSFTEESRCACELIEGHGCPVRHLEADCGAVVLSFVAADLESFRDIVVNLKSAFDGVSLRRLTQSEPDSATGSLVFVDRDELTARQREVLETAHEMGYFEHPREANATEVAAALDINRSTFTEHLSAAQSKLLDTILDV
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of 2-phosphoglycolate.
Sequence:
MKFKAIVIDIDGTITCENRELHLGAVKKIRILKVPVVLATGNILCYARTASKLIGLDGAVIAENGGAVTVRYDLNGTFEESLEECEKAFSFLSEYFKLTKLDPFYRKTEIALRRDFNLEKARTLLETQPFDVEMVDTKYAVHIKSTRINKGSGLRKLAEIMGLEAEDFVAIGDSENDIEMFEAAGFGIAVANGDERIKEAANYVTEASYGDGAVEAIEFLESNGWI
The following text describes a protein:
Function:
Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose. Acts only on small linear 1,5-alpha-linked L-arabinofuranosyl oligosaccharides.
Subcellular Localization:
Secreted.
Sequence:
MTTFTKLSEQEAPGISIHPDRRISKINPNIYAGFAEHMGRCIYGGIYDPGNPLSDENGFRKDVLEALKELKVPVIRYPGGNFTATYHWIDGVGPRDQRPARPELAWLGTETNQFGTDEFLKWCEVLGTEPYLCLNMGTGTLDEALAWVDYCNGTRDTYYANLRRKNGREEPYNVKYWALGNEVWGPWQVEQSTKEEYAHKAYQWAKALKLLDPSIELILCGKEGPTSWDYYTLKQTMLPVHSPLSTSAVPLIDMHSIHLYTAHSSHLPNVTAPLAAERAIEITSSLIDLARVENGVPPEQRRPTICFDEWNVWDPIRAEGSKGAEESYNLSDALAVGVWLNVFVRKSKDVGMACIAQSVNVISPLMTTKDGIVKQTTWWPLYLFSNYMRGWTISAHISVSAYEGETHPKWVRGVKDTPWLDVSATLGEDGYVNVVVINIHEEKGIEAKLDGPSGEVTVFTVTGDNPAVTNMKGKEEVGLVETKWDAQGPYVFPKHSLTLLRWKA
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (YhdL) until released. This sigma factor is involved in the maintenance of membrane and cell wall integrity in response to environmental stresses including salt, acid, ethanol and antibiotics stress. Partially regulates transcription from a number of genes including disA. Associates with RNAP core under all growth phases.
Sequence:
MTIDEIYQMYMNDVYRFLLSMTKDKHLAEDLLQETFMRAYIHIHSYDHSKVKPWLFQVARNAFIDYVRKHKKEVTISDDLIGSLFQNAVQSPAHQVEIKEVLTGYMSELPDNYREALTLYYLKELNYKEASHIMNISEANFKSVLFRARQRLKALYNRGVNDE