lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Appears to initiate or participate in signaling events that regulate the actin recruitment, which ultimately leads to internalization.
Miscellaneous:
MISCELLANEOUS: Transcribed from mid to late cycle in the chlamydial developmental cycle.
Subcellular Localization:
Secreted. Note=Secreted via type III secretion system and translocated into host cell.
Sequence:
MTNSISGDQPTVTTFTSSTTSASGASGSLGASSVSTTANATVTQTANATNSAATSSIQTTGETVVNYTNSASAPTVTVSTSSSSTQATATSNKTSQAVAGKITSPDTSESSETSSTSSSDHIPSDYEPISTTENIYENIYESIDDSSTSGPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYESIDDSSTSDPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYENIYESIDDSSTSGPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYESIDDSSTSDPENTSGGAAAALNSLRGSSYSNYDDAAADYEPISTTENIYESIDDSSTSDPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYENIYESIDGSSTSDPENTSGGAAAALNSLRGSSYTTGPRNEGVFGPGPEGLPDMSLPSYDPTNKTSLLTFLSNPHVKSKMLENSGHFVFIDTDRSSFILVPNGNWDQVCSIKVQNGKTKEDLDIKDLENMCAKFCTGFNKFSGDWDSRVEPMMSAKAGVASGGNLPNTVIINNKFKTCVAYGPWNSREASSGYTPSAWRRGHQVNFGEIFEKANDFNKINWGTQAGPSSEDDGISFSNETPGAGPAAAPSPTPSSIPVINVNVNVGGTNVNIRDTNVNTTNTTPTTQSTDASTDTSDIDNINTNNQTDDINTTDKDSDGAGGVNGDISETESSSGDDSGSVSSSESDKNASVGNDGPAMKDILSAVRKHLDVVYPGDNGGSTEGPLQANQTLGDIVQDMETTGTSQETVVSPWKGSTSSTGSAGGSGSVQTLLPSPPPTPSTTTLRTGTGATTTSLMMGGPIKADIITTGGGGRIPGGGTLEKLLPRIRAHLDISFDGQGDLVSTEEPQLGSIVNKFRKETGSGGIVASVESAPGKPGSAQVLTGTGGDKGNLFQAAAAVTQALGNVAGKVNLAIQGQKLSSLVNDDGKGSVGRDLFQAATQTTQALSSLIDTVG
The following text describes a protein:
Function:
Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MENGIKESPVGLNKNGALAILPTPLVSEGHKNHKSVLNSLTSGALAGAVAKTAVAPLDRTKIIFQVSSNRFSAKEAYRLIYRTYMNDGFLSLWRGNSATMVRVIPYAAIQFCAHEQYKKLLGSYYGFQGSALTPIPRLLAGALAGTTATLLTYPLDLVRARMAVTQKEMYSNIIHVFMRMSREEGLKSLYRGFTPTVLGVIPYAGISFFTYETLKKLHAEHSGRTQPYTFERLLFGACAGLFGQSSSYPLDVVRRRMQTAGVTGHTYGSIIGTMQEIVAEEGFIRGLYKGLSMNWVKGPVAVGISFTTFDLTQILLKKLQQISHIQR
The following text describes a protein:
Function:
G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
The following text describes a protein:
Function:
Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Sequence:
MSSSGLLKPATLDDVFQKLEDLCKLFPPQEKTVNVTSLKTGRILAEDIITEYDIPAQRTSIVDGFAIIVNQLGTKREIVGLSTAVTPYNAELISNECVRITIGGVVPDGADTVVPIENVALLKEEKCIEVLRKPKEGDNIREVGSEAKTGEILLKDGHHLDTMSITLLHALGISQVEIYKKPRVCVLSIGSDLNSNKMYGSFNRSQLLELFQSQGFTAIDAGSSTEHITEVEEKIRTAASFACVLVTVGGAQVIREVAKTLKFKFEIQDVDSTPGNFTVSTGKIDETPVVLSIFPEYHVSSWIGANLFVSPILRAMEGQNSETSHRFKAELTQPISKTSETRFLRARSEVSKGNLISTPLGCEDIFGANSILEVKSNTCFSAGDVVDLRFA
The following text describes a protein:
Function:
Seems to regulate the expression of the operons for the enzymes involved in D-galactarate, D-glucarate and D-glycerate utilization.
Sequence:
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLRKYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDLNQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNSFGRWDAEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQRMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKTMDNNGLLRRTLAAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER
The following text describes a protein:
Function:
Regulator of histone epigenetic modifications and chromatin compaction into the sperm head, required for histone-to-protamine (HTP) transition. HTP is a key event in which somatic histones are first replaced by testis-specific histone variants, then transition proteins (TNPs) are incorporated into the spermatid nucleus, and finally protamines (PRMs) replace the TNPs to promote chromatin condensation.
Subcellular Localization:
Nucleus. Note=Forms condensates in the nucleus through liquid-liquid phase separation.
Sequence:
MTQTLDTKEDPLNLGGGWASSAPLRTWSFGPRRRRGAPVYRRRPRYGPKAEYEPPRKQAKQQYGPGPWFQPPWRPYWAVYSNWGRWRGPWCPPPAGFRKPPGRVQVIRVYGLHPLCLCCCSCCHGPWNPGWARPPGRKKRWGRRGRGLRRHPRRSAQRSPPVDLSTLLRPVNLYGWRAPGMRAPRNTTQFIMNQIYEDMRQQEKLERQQEALRAQQAQAASTASPEGAFGNDVPPSGGQEDEELQDTLYSFVRNPSLVFSPDPDEEKQTATSQLVEEEEEGEREEEEEEWCDEEECDGKELESQEEDEESEAKDEEDEESEAKDEEEGEEADYMEEREEEDEEDEAEEIAEEEEGLAEDEQTEEENHLPLEMPLSFLVGAEEERENFMNCTYLSPKQGIPKVAQEALFMVQDINC
The following text describes a protein:
Function:
Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MAVLLVAVLASSLYLQVAADFDGRWPRQIVSSIGLCRYGGRIDCCWGWARQSWGQCQPVCQPQCKHGECVGPNKCKCHPGFAGKTCNQDLNECGLKPRPCKHRCMNTFGSYKCYCLNGYMLMPDGSCSSALSCSMANCQYGCDVIKGQIRCQCPSPGLQLAPDGRTCVDIDECATGRVSCPRFRQCVNTFGSYICKCHTGFDLMYIGGKYQCHDIDECSLGQHQCSSYARCYNIHGSYKCQCKDGYEGDGLNCVYIPKVMIEPSGPIHMPERNGTILKGDGGYANRIPDAGSTRWPLKTPYIPPPVITNRPTSKPTARPTPNPTPQPTPPPPPPLPTELRTTPLPPTPERPATSPTTVAPATQVVTVDNRIQTDPQKPRGDVFIPRQPSNDLFEIFEIERGVSADEEAKDDPGILIHSCNFDHGLCGWIREKDSDLHWEPTRDPAGGQYLTVSAAKAPGGKAARLVLPLGHLMHSGDLCLSFRHKVTGLHSGALQVFVRKHGTHGSALWGRNGGHGWRQTQITLRGADVKSVIFKGEKRRGHTGEIGLDDVSLKRGRC
The following text describes a protein:
Function:
Capsid decoration protein which helps to stabilize the capsid against extremes of pH and temperature. Once maturation and expansion of the capsid has occured, trimers of soc attach the interfaces between the hexamer of the major capsid protein. Acts as a 'glue' between neighboring hexameric capsomers. Dispensable for the head morphogenesis and phage infection.
Subcellular Localization:
Virion. Note=870 copies decorate the capsid.
Sequence:
MASTRGYVNIKTFEQKLDGNKKIEGKEISVAFPLYSDVHKISGAHYQTFPSEKAAYSTVYEENQRTEWIAANEDLWKVTG
The following text describes a protein:
Function:
Required to generate and maintain the structure of the tubular endoplasmic reticulum network and the vacuole. Induces high curvature in membranes and causes membrane tubule formation. Involved in membrane/vesicle trafficking.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSSFQAQAQNYLSQIDKSTKNFGVLDQFEQRSGLPRSYAVLGAGGLYFFLILLNFGGIGQLLSNIAGFVIPGYYSLVALKTTTKDDDTKLLTYWVVFAFINVIEFWSNTILYYVPFYYLIKTGFLIYLSSFGGSTLVYNSVIKPLSDKYVKVENPIASKIQETAEGVSTGVHY
The following text describes a protein:
Function:
Transcriptional repressor. May modulate BMP and TGF-beta signal transduction, through its interaction with SMAD proteins.
Subcellular Localization:
Nucleus.
Sequence:
MFQEPVTFRDVAVDFTQEEWGQLDPTQRTLYRDVMLETFGHLLSVGPDLPKPAVISQLEQGAELWVADRGGSQACHPGWILEPEDHTLLKDQDLPKMKPSPITEKDGFAKAVSCHSMTGIYRENDGQRQALKKDQSNLRQLNGPKEIPVQSQSYKSLGLVETCVLGLNTDLLPDISRIEYGYTYGSQVKNSEHNPSLVSQQTDSPASQPFDDNGSQKAFDQIMPITELTKSQVQDKPYKCTDCGKSFNHNAHLTVHKRIHTGERPYMCKECGKAFSQNSSLVQHERIHTGDKPYKCDECGKSFCHSTHLTVHRRIHTGEKPYECQDCGRAFNQNSSLGRHKRTHTGEKPYTCSVCGKSFSRTTCLFLHLRTHTEERPYECNHCGKGFRHSSSLAQHQRKHAGEKPYECRQRLIFEQAPALTKLEWTEPLSCDPPLSQSERTQQSDRPFKCNQCGKCFIQSSHLIRHQITHNREEEPVRGRSRRREQHCRPGSKLIRNPHSNSKEVPIAQAKAGQASRALALFDLHEIMQEKNSVHVIGVEEPSVGNSMLFDIRESR
The following text describes a protein:
Function:
Receptor that plays a role in T-cell activation, proliferation, survival and the maintenance of immune homeostasis. Functions not only as an amplifier of TCR signals but delivers unique signals that control intracellular biochemical events that alter the gene expression program of T-cells. Stimulation upon engagement of its cognate ligands CD80 or CD86 increases proliferation and expression of various cytokines in particular IL2 production in both CD4(+) and CD8(+) T-cell subsets. Mechanistically, ligation induces recruitment of protein kinase C-theta/PRKCQ and GRB2 leading to NF-kappa-B activation via both PI3K/Akt-dependent and -independent pathways. In conjunction with TCR/CD3 ligation and CD40L costimulation, enhances the production of IL4 and IL10 in T-cells.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MILRLLLALNFFPSIQVTENKILVKQLPRLVVYNNEVNLSCKYTYNLFSKEFRASLYKGVDSAVEVCVVNGNYSHQPQFYSSTGFDCDGKLGNETVTFYLRNLFVNQTDIYFCKIEVMYPPPYIGNEKSNGTIIHVKEKHLCPDELFPDSSKPFWALVVVGAVLVFYSLLVTVALCAYWIKSKSSRILQSDYMNMTPRRPGPTRRHYQPYAPARDFAAYRS
The following text describes a protein:
Function:
Cohesin cofactor dispensable during the meiotic division but playing an important role in DNA repair by homologous recombination (HR) probably by helping SMC5/SMC6 complex. Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Subcellular Localization:
Nucleus.
Sequence:
MFCFRQMYLFLSMLVHGDEEGKSEGDISREKESILTINSILHSIKHSEDAVDSAISKNSYAVSDLGLMIAKRLVPNLDDLKESEASVSLPPSLYKQLEKGEEKDQSLVELKTWLADESVMVHFESIKFETNGTQLKSEITEDEAMKDSETEGNEVPLGKIMERLKARSKMRKEVKDDPSPPEVRAEHDLDILKVLREIDSNNAGDDNKLDASNGHESAVKTKATNKRQKRKTGTDISVPKGAKRQRSSSSSGHKLSAKIKVSIENEDDLLSMSEDKSSEENVYEPEESDLLASSIRKKTSFLPKQKRKSTDKTCGDTHEVGADSRGLKKSKQNKEAVDTHVESNNMSGSHKQQKKKSVAGLAKCTSKGDTAPTVDLIGCRIKVWWPMDKKFYEGVIKSFDTQKNKHVVLYDDGDVEVLRLEKECWELVGGGQKPVKGSNSKKGSNSKKVSRYEKVSGERKNKALAASKQKKETDNMSPVSQVRGKRTPRKNLKYGQKGPSKSSFSRGRLLLGKPLETSKYNENTLSSGNSEGEQKESMHGSLSEHELSDKDDRSYSDGKPVADDDDRSSGMEESVKEENPLENKEFEDEPGTPQDSRGSDEEISSHEKPQPDVSTEKSNDDAERSDSQGSLGDNADSHSSDRGDSERSSATKSDEELSDDELLSTWKSRAGKSAGGK
The following text describes a protein:
Function:
3' exoribonuclease required for 5S rRNA maturation and for the proper maturation of the 5' cistron of the tRNA-Arg3 dicistronic gene. Involved with REX2 in the maturation of the 5.8S rRNA, and with REX2 and REX3, in the 3' processing of the U5L snRNA.
Subcellular Localization:
Nucleus.
Sequence:
MQVEGPDTNFVSDLALGSKKRRLSKTSVQEDDHTNVVSEVNKNKKKKKAKPMTCTLLKSVVEKGIGIKDVRDMTQYLLQAENNSPKWIDICNRSSLQKMIVLFIPGLQPDDFENGKNTFNEISDDNFKYIPGEIASTFHTFPVMAPGSKMTLFSPYNSFINVGLSKMEKINKLKELQKKKKITINDLVLSEQQLVANDYPLDSGDTNFDTDWVQTVDFTHGGSHIFALDCEMCLSEQGLVLTRISLVNFDNEVIYEELVKPDVPIVDYLTRYSGITEEKLTVGAKKTLREVQKDLLKIISRSDILIGHSLQNDLKVMKLKHPLVVDTAIIYHHKAGDPFKPSLKYLSETFLNKSIQNGEHDSVEDARACLELTKLKILNGLAFGIGINTENLFTKLHRFEVKTVLLNDMIIKNHTEDDSKGQLIRCVEDDETWTHIHENLNKDVKLIVGRIKNLERSRNYNKKPRKETPSFDASMVLHDIGQHLTQLYENATPGTMILIMSGTGDTRPWNNLSTELEFIQDKKERLDKRREREPEIVEAIKLARGGVASFTVK
The following text describes a protein:
Function:
An ATP-independent periplasmic chaperone, decreases protein aggregation and helps protein refolding. Binds substrate over a large region of its convex inner surface. Substrate protein folds while it is bound to chaperone. Increasing Spy flexibility increases its substrate affinity and overall chaperone activity (shown for 3 different substrates). Protects proteins in vitro against tannin inactivation; tannins have antimicrobial activity. Overexpression enhances the stability of otherwise unstable periplasmic proteins.
Subcellular Localization:
Periplasm.
Domain:
Has an elongated cradle shape.
Sequence:
MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKFGPHQDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKVKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATAE
The following text describes a protein:
Function:
A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity).
Sequence:
MVFKMMYSEAILDYANSKKFRGKLDDATVIEEGKNISCGDEITLYLKVEDGVVKDAKFEGMGCVISQASASLMLERIIGERVEEIFSLIEEAEKMSRGENFDEGKLKNVTLMSDIKNYPARVKCFILAWKTLKEALKKISRP
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MAGLREQIPDMEQLSNELLKLMAENKGTEKLKDNLPKQEKMFDKLLDTQKTTKQLIKDLIAAEEAAAQKLHEREQELNASLQKLKKIEDELCQQNKDATLRTSIKELSKELEALKEEIRQQERKAAENVDASTSAKYLVHLYYQISHIDWDYSCEPNMIKGIHYGPDIAQPINLDSTLHSRCFISDYLWSMVNTSWSKK
The following text describes a protein:
Function:
Necessary for normal cell division and for the maintenance of normal septation.
Sequence:
MSLLIEQARYHLSAHNARQLPDDGGYEVAFAGRSNAGKSSALNALTRQNSLARVSKTPGRTQQLVFFQIQPERYLVDLPGYGYAKVPQDLQAHWQAFIDRYFRTREALRGLVVVMDIRHPLKDYDLQMLGYAAERGLPAHGLLTKADKLGRGQQMQTLQKVKKEVSSRFGDSVTVQTYSGESRQGVDELRGIVGGWLGLDVEPPADA
The following text describes a protein:
Function:
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
Subcellular Localization:
Cytoplasm.
Domain:
The open, reduced form of PAPS reductase is able to bind PAPS, whereas the closed oxidized form cannot. A movement between the two monomers of the dimer may allow this switch in conformation to occur.
Sequence:
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
The following text describes a protein:
Function:
Ubiquitin-binding protein which acts as an adapter for ATPase cdc-48.1 and/or cdc-48.2, conferring substrate specificity. Together with ubxn-2 and ubxn-3, plays a role in hermaphrodite spermatogenesis probably by promoting the degradation of sex determination terminal factor tra-1.
Subcellular Localization:
Cytoplasm, perinuclear region. Note=Colocalizes with cdc-48.1 to the perinuclear region in spermatocytes.
Sequence:
MSIAQQLMDMGFPADKAEAAAGNNRNLDQALDWIEKDGAGVPMETDAPAQAAPGAADSGAPPVAASFKCDDCGKLLANDDAIMFHASKTKHENFSESSEAIKPLTAEEKAAKVLEIREKIKVHQAKKAKLEAEENREKEKKRREDGKAMISHKEAARDREIREAAQDRRREKNEDEIARKRVLEQIRLDKEARKAKASGQPVPEAKPAPSAAPVAPPKDYSTTTLQFRLLDGQTVRQQFEANEPLAMVRAWVETNHANGVPFTLMTPFPRKVFTEDDMGTPLKVLNLVPSANVILNRAA
The following text describes a protein:
Function:
Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
Subcellular Localization:
Nucleus.
Sequence:
MASVKSFKRKYLKLRKSFDSVVLETEEIEQKIAEISEVYRRILLENAHLNDLLIDMNSTVLPTPPASPPGSPYWEAKPVSHTVFLESPSDVFTLEKPIASTHRWLSKLTALSKSTNSTLSTPKSFHSPLQSRGISPSSAQSSAAVSSSRKQKRKRTSEGPSERRARKK
The following text describes a protein:
Function:
Involved in restoring normal CheY-P levels following the addition of attractant by increasing the rate of CheY-P hydrolysis. Is only 6% as active as FliY, which indicates that CheC may function after addition of an attractant to cope with increased levels of CheY-P whereas FliY may function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P. In addition, it was shown to prevent methylation of the methyl-accepting chemotaxis proteins (MCPs). Inhibits CheD.
Sequence:
MSIFNGIKEEQMDILREVGNIGAGHSASAMAQLLNRKIDMEVPFAKLLSFDELVDFFGGADVPVASIFLRMEGDLTGSMFFIMPFFQAEQFIRELIGNPDFDIEDLGEDHMSSSALHELGNILAGSYLTALADLTKLQLYPSVPEVSLDMFGAVISEGLMELSQVGEHAIVVDTSIFDQSHQQELKAHMFMLPDYDSFEKLFVALGASL
The following text describes a protein:
Function:
Influences biofilm formation. Represses fimbria genes in 8 hours biofilms. May act in response to the combined activity of several toxin-antitoxin (TA) systems.
Sequence:
MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGAPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
The following text describes a protein:
Function:
Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MAHWSRFEKELELETKRLISHFTAIQDEEDQNFQMALKFTWSNFKFHRFLEANRHNVQRSINGIHEKLMVHSDLSKAESWTRLTEEFLTSPLPNTDGTKTDIHYGILALLLHLSDSPSNTNYCERPRLKETEKEDTFDWAKYLMEGEDFDPGPFPDTPEWSEEESEEDDSQQPLSREDSGIQVDRTPQEDHEQNDKTVQVTWTVGEPDSRAWLEQHIVTSYWVPNSPRFPHSLHLHSNLYNVWDQHLYNTGPLYLPEEKSFVTETQVIRETLWLFSGVKKLFIFQHNDGKVTVRNDVVVTHLTNNCLHSVLEHIAAYGQAVSRLQKFIDEVTGHSAEPCPPGLNSSSSSSKKSSEPPFRTYQAFVWALYKYFTSFKEELNAIEKDIIAKDETVTLSSVLERLSPHLAQITMLHRVFCTGVAEVPPGTPNVLRASHLLNTLYKAIIEYDSVGEASEQSVALLFSLWVETVRPYLEIVDEWIVHGHLFDPAKEFIIQRNKDVPVNHRDFWYATYTLYSVSEMVESEERLSDAASGSSGGEQTSSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLDCKETEQSDGSSRDAERKSLYTLFLESVQTRLRRGEESPTNTVTEQQATKKSLIKMQSIVARHLELDDIHDPLLAINFARLYLEQNDFHEKFSGGSVILDRSSESVTCQTFELTLRSCLYPHIERRYVECCGNLMRTLKKDYRLLGYLQAMRNYFLLEAGDTMYDFYTAIFDKVLEKESWQQLAFLNVQLQESVGQRHPEDSHRLSIFLETIDPARKKQPVNNLDGLTLSYKVPWPVDIVISSECQKIYNQVFLLLLQIKWAKYSLDTLRFSDLTVAAKRKEGGQPEENTAKESINQQIHRMFLLRVKLMHFVNSLHNYIMTRILHSTGLEFQHQVQEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNLVLIFSDRWQAGFGAWKIESIDKMESDFKNCHMFLVTILNKAVCRGSFPHLESLAMSLMAGFEQC
The following text describes a protein:
Function:
SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MAYISENELKFLRLLERTKRLTKEDMSANVWKVSAATKILNKMIYTLQNDETTNDILHEYRQEVLQLKLLAEAESKSSAEERLKVIEKIPRVFPDVQVTVADSKNDNEAESYDFEKESAAGLRATQRSIYRSDLRKQLLSSNKHRAQDTSEDQEFMKNELVEEELANSLATMARSFKTMMSAAGDVIKEDTERAILMAKEVDDNKTALGIQSERVERHAYKCGYDCFKVMLIVLIFMSFVSMVLMMKIFKKAST
The following text describes a protein:
Function:
Probable receptor that acts as an upstream signaling protein to promote the guidance, migration and positioning of the right Q neuroblast (QR) and its descendants along the anteroposterior body axis, and also the anterior migration of BDU interneurons during larval development. Associates with and recruits the downstream components tyrosine kinase abl-1 and the tyrosine kinase adapter protein sem-5 to the leading edge of migrating Q neuroblasts and their descendants to activate signaling through the two parallel wve-1 and wsp-1 pathways, respectively, and direct migration along the anteroposterior body axis. Involved in cytoskeleton dynamics regulating the organization of the actin cytoskeleton at the leading edge of migrating cells to ensure correct Q cell polarity and promote migration. Role in cytoskeleton organization may be by activation of the wve-1 and wsp-1 pathways which recruit the Arp2/3 complex to the leading edge of migrating cells. Plays a role in regulating the asymmetric distribution of the actin cytoskeleton-binding protein cor-1 in Q neuroblasts which is required for the anterior migration of QR neuroblasts.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, axon. Cell projection, dendrite. Note=Localizes to the leading edge of migrating Q-neuroblasts.
Sequence:
MTKLLIALILFSICWKPYSAEPIASFFDGLDSRNECKARLDRRLTGFSGLLYSHSKYGQEPYNTSRNCVLMLVAPIGYSIRVRALQFDVASTENARTCEKDTLHVFDHETTLDPESYAPARIDDITSPGPIIGQFCGHFENRILNTSSHNALTLWWHSNPNGSNSKGFKLHWGSFRVSKTGNCVTGEFSCGNGECIPIESACDRFADCSNGEDLIHSRQMAANCQNIELDPLTTVSGVFVLLFSATIILSLCGFIMFVCCLCKCLKSTIPIKGASSHTTTTTATDYKPDPPQFYPPSPPKMPPPSAASSYTPRLHHHFEGPLVPSETSAFHSSNRMQNHYSVNSDINGDYTYVRNDVHRNLL
The following text describes a protein:
Function:
GDH is probably involved in energy conservation rather than in sugar metabolism.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein; Periplasmic side.
Sequence:
MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAISPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK
The following text describes a protein:
Function:
May be involved in neurite outgrowth.
Subcellular Localization:
Cell membrane; Lipid-anchor. Cell projection, growth cone. Note=Highly enriched in growth cone.
Sequence:
MRDCCSSPKAIPAPPRHALDQSLGMDPRHTSSSGAAEGASCSERPAGSLACPSPNCSPLPETPRAHGALTSDNSGTTLFGKPEPMSSAEATPTASEIRNPVFSGKMDGNSLKQADSTSTRKEEAGSLRNEESMLKGKAEPMIYGKGEPGTVGRVDCTASGAENSGSLGKVDMPCSSKVDIVSPGGDNAGSLRKVETISSGKMDPKTENVMHSRRERPGSTGEGDLVSLRENDMKPPDNTDSASTKKTDPEFSGKLTPGSSGKTELVSSVTVAPVTSENVNPVCSGGAGPAAVGNSETLSSVKKDPQLLGKKEAVSSGEGGSVSVRMAETVSARQPEGMFPAKTDSTSSNSTGPSGRADPVSLRNSELVSPVKPERLSSGQAERVSLVKTETLSSGKEDPRSSRRVDHTTVTGNMQTSQKGNPESSGKTDLGSSSSGDTRSLGTWGSLSAAKAEVTEGKGDPQPWKKASLPASEKTDPLASSKAGSASQGKAETVSPGEVDAMTLGKTVPTSSGKTALVSPGKVDLMTSERAEGIPELQASEKGNPVNSTRVDTGATGSTEPKSGVKVITQIPGATSPGKVETPSLQKEQPQLSEKTDPSRKVDPPTTVEPVSLGKADSASPSPRKAESQTSAKTVPQAPDKATSSLRQSDGTPYSSAQPQRDTRSIGSLPEREPSASTSQKDLAAAAAQKSPSAEAAAPPPGPRTRDNFTKAPSWDAGAPPPREDAGTQAGAQACVSVAVSPMSPQDGAGGPAFSFQAAPRAPSPAPRPPSRRDAGLQVSLGAAETRSVATGPMTPQAAAPPAVPPVFPEVRVRPGSVLAAALAPQEATEPVRDVSWDEKGMTWEVYGASMEVEVLGMAIQKHLERQIEEHGRQGAPAPAPPPAVRAGPGRAGSVRTAPAEGAAKRPPGLFRALLQSVRRPRCCSRAGPTAE
The following text describes a protein:
Function:
Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPLVDPVTMSSSAIVKGAVAQSTSTTKSTPGSQATESSTTTAGSSSSLATLRPVQIKQTPAAQTVRHALPAALTALYLLRFDALVTNPVPVMLNALPVVAAFQMTYALLCLPAAGEPASKSNRKPRPGEKKKGGDIGSSTIITALLASVLTSIVTPFLYFAMVLFGAPFLTHGSHTFLCAAHLALLTLFPLFYVHGVDSAAWAAVGGFRAPLDETFGGLVGGIVGAWLGAVPIPLDWDREWQRWPVTILCGAYGGYLLGRVLGGTLFWGKKF
The following text describes a protein:
Function:
May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Miscellaneous:
MISCELLANEOUS: Contains 2 motifs that are conserved in esterases, but it is unlikely that this protein belongs to the catalytically active pectin esterases.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MTLASPRVSNSKTTVLLFPRKVSSIAFAIGGLTSFVIFASLLLFTYPIGSSVTDYFYRTETTQNVQFHHSIHDPDRNPSPVSSSESPPVLTQDSDDKVLPKGSHDSNDVRLGEETNSGKSSNVSIDEEATQDHVETECDLYHGNWFYDPMGPLYTNNSCPLLTQMQNCQGNGRPDKGYENWRWKPSQCDLPRFDAKKFLELMRGKTLAFIGDSVARNQMESMMCLLWQVETPVNRGNRKMQRWYFRSSSVMIARMWSSWLVHQFNEPFGFATDGVTKLKLDQPDERIIEALPNFDVVVLSSGHWFAKQSVYILNDQIVGGQLWWPDKSKPEKINNVEAFGISVETIIKAMAKHPNYTGLTILRTWSPDHYEGGAWNTGGSCTGKVEPLPPGNLVTNGFTEIMHEKQATGFHRAVADDKLGNRSKKLKLMDITEAFGYRHDGHPGPYRSPDPKKITKRGPDGQPPPQDCLHWCMPGPVDTWNEMVLEIIRRDFEGRQSSPSS