lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Esterase involved in the biosynthesis of lignin. Hydrolyzes caffeoylshikimate into caffeate and shikimate. Together with 4-coumarate--CoA ligase (4CL), acts on an alternative reaction for the formation of caffeoyl-CoA and bypasses the second reaction of shikimate O-hydroxycinnamoyltransferase (HST). Also accepts 4-coumaroylshikimate as substrate, but with lower activity. According to PubMed:20345607 and PubMed:22915575, possesses monoacylglycerol O-acyltransferase, monoacylglycerol lipase and lysophospholipase activities in vitro. With the association of ACBP2, may promote the degradation of lysophosphatidylcholine and detoxify the peroxidized membrane in response to cadmium-induced oxidative stress. However these results require additional confirmation in vivo.
Miscellaneous:
MISCELLANEOUS: Mutant plants exhibit increased sensitivity to zinc, cadmium and H(2)O(2).
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Note=Colocalizes with ACBP2.
Sequence:
MPSEAESSANSAPATPPPPPNFWGTMPEEEYYTSQGVRNSKSYFETPNGKLFTQSFLPLDGEIKGTVYMSHGYGSDTSWMFQKICMSFSSWGYAVFAADLLGHGRSDGIRCYMGDMEKVAATSLAFFKHVRCSDPYKDLPAFLFGESMGGLVTLLMYFQSEPETWTGLMFSAPLFVIPEDMKPSKAHLFAYGLLFGLADTWAAMPDNKMVGKAIKDPEKLKIIASNPQRYTGKPRVGTMRELLRKTQYVQENFGKVTIPVFTAHGTADGVTCPTSSKLLYEKASSADKTLKIYEGMYHSLIQGEPDENAEIVLKDMREWIDEKVKKYGSKTA
The following text describes a protein:
Function:
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development.
Subcellular Localization:
Nucleus.
Sequence:
MSIPIQSDEEFNSTFEEKKGRPVILFFTAAWCGPCQMIKSFVEEQAAKHQDRLSVLKIDVDECEAACEKYGVASMPTFILIVNGVTKDTFNGANNGKFSEMISKALE
The following text describes a protein:
Function:
Putative transcription factor that may be involved in the light input to the circadian clock but does not affect flowering time.
Subcellular Localization:
Nucleus.
Sequence:
MLKVESNWAQACDTCRSAACTVYCRADSAYLCSSCDAQVHAANRLASRHERVRVCQSCERAPAAFFCKADAASLCTTCDSEIHSANPLARRHQRVPILPISEYSYSSTATNHSCETTVTDPENRLVLGQEEEDEDEAEAASWLLPNSGKNSGNNNGFSIGDEFLNLVDYSSSDKQFTDQSNQYQLDCNVPQRSYGEDGVVPLQIEVSKGMYQEQQNFQLSINCGSWGALRSSNGSLSHMVNVSSMDLGVVPESTTSDATVSNPRSPKAVTDQPPYPPAQMLSPRDREARVLRYREKKKMRKFEKTIRYASRKAYAEKRPRIKGRFAKKKDVDEEANQAFSTMITFDTGYGIVPSF
The following text describes a protein:
Function:
Depending on the conditions (growth phase and medium), acts as a positive or negative regulator of gadA and gadBC. Repression occurs directly or via the repression of the expression of gadX. Activation occurs directly by the binding of GadW to the gadA and gadBC promoters.
Miscellaneous:
MISCELLANEOUS: GadX and GadW are part of a complex system required for acid resistance via the regulation of gadA and gadBC. Many of the described circuits use mutants missing one of the network components. In the wild-type situation, however, many of the scenarios are not easily observed.
Sequence:
MTHVCSVILIRRSFDIYHEQQKISLHNESILLLEKNLADDFAFCSPDTRRLDIDELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPMPLVTAIFDSFNESGVNSPILSNMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAERMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYFINTFRQYYGVTPHQFAQHSPGTFS
The following text describes a protein:
Function:
Involved in plant defense. Confers resistance to the fungal pathogen T.viride through recognition of the EIX elicitor protein.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MDKWKYARLAQFLFTLSLLFLETSFGLGGNKTLCLDKERDALLEFKRGLTDSFDHLSTWGDEEDKQECCKWKGIECDRRTGHVTVIDLHNKFTCSAGASACFAPRLTGKLSPSLLELEYLNYLDLSVNEFERSEIPRFIGSLKRLEYLNLSASFFSGVIPIQFQNLTSLRTLDLGENNLIVKDLRWLSHLSSLEFLSLSSSNFQVNNWFQEITKVPSLKELDLSGCGLSKLVPSQADLANSSLISLSVLHLCCNEFSSSSEYSWVFNLTTSLTSIDLLYNQLSGQIDDRFGTLMYLEHLDLANNLKIEGGVPSSFGNLTRLRHLDMSNTQTVQWLPELFLRLSGSRKSLEVLGLNENSLFGSIVNATRFSSLKKLYLQKNMLNGSFMESAGQVSTLEYLDLSENQMRGALPDLALFPSLRELHLGSNQFRGRIPQGIGKLSQLRILDVSSNRLEGLPESMGQLSNLESFDASYNVLKGTITESHLSNLSSLVDLDLSFNSLALKTSFNWLPPFQLQVISLPSCNLGPSFPKWLQNQNNYTVLDISLASISDTLPSWFSSFPPDLKILNLSNNQISGRVSDLIENTYGYRVIDLSYNNFSGALPLVPTNVQIFYLHKNQFFGSISSICRSRTSPTSLDLSHNQFSGELPDCWMNMTSLAVLNLAYNNFSGEIPHSLGSLTNLKALYIRQNSLSGMLPSFSQCQGLQILDLGGNKLTGSIPGWIGTDLLNLRILSLRFNRLHGSIPSIICQLQFLQILDLSANGLSGKIPHCFNNFTLLYQDNNSGEPMEFIVQGFYGKFPRRYLYIGDLLVQWKNQESEYKNPLLYLKTIDLSSNELIGGVPKEIADMRGLKSLNLSRNELNGTVIEGIGQMRMLESLDMSRNQLSGVIPQDLANLTFLSVLDLSNNQLSGRIPSSTQLQSFDRSSYSDNAQLCGPPLQECPGYAPPSPLIDHGSNNNPQEHDEEEEFPSLEFYISMVLSFFVAFWGILGCLIVNSSWRNAYFKFLTDTTSWLDMISRVWFARLKKKLRRAR
The following text describes a protein:
Function:
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
Miscellaneous:
MISCELLANEOUS: Lysozyme C is capable of both hydrolysis and transglycosylation; it also shows a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides.
Subcellular Localization:
Secreted.
Sequence:
KVYDRCEFARILKKSGMDGYRGVSLANWVCLAKWESDFNTKAINRNVGSTDYGIFQINSRYWCNDGKTPKAVNACHISCKVLLDDDLSQDIECAKRVVRDPQGIKAWVAWRTHCQNKDVSQYIRGCKL
The following text describes a protein:
Function:
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Sequence:
MAPLIPCTTTNSISPTSGVAFTINRRSNCYLSRFNITIKLNRQTLQAQKYTLPLSKSVGLQTFSQIRIGSVFYVHSVGAATDAEGTSGGSFKRSRYVRKSEMPPVNNEDLIPGATFTGKVRSIQPFGAFIDFGSFTDGLVHVSNLSNEFVKDVGSIVSVGQEVVVRLIEANMETRRISLSMRNVMTSANDEEDFDENLIQQGVVHTATNPFVLAFRTNKVISAFLDELEKEKQNEHDLLVADISDKIVAQVKENAVDEKLVKGTSAACIGSSSYKDGKESRNLPMDVYNEYKGDLVGGARDHVII
The following text describes a protein:
Function:
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Subcellular Localization:
Cytoplasm.
Sequence:
MEARLVLGSSSERRKAVLESFRIPFICVSPDFDERSIVYSGDPFEYTKELAWNKANVVRSQGFSDALIITADTVVVYKGEVFNKPESEEHAVEMLRTLSGSSHSVITTLVLMQNEKVLSASENTQVSFIDIPPQHLKTYVRSFSSLKRCGGYCVQDGGGLIIKQIEGCVYNIQGLPIKTLNQLLMEFNISLWDYLV
The following text describes a protein:
Function:
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
Subcellular Localization:
Cytoplasm.
Sequence:
MKKAGILNRHLAGALAELGHGDGVLVCDAGMPVPDGPRVVDLAFRAGVPSFAEVVDGLLAELVVEGATAATEVREANAECAALLDGLFPALALVPHERLKELSAGARLIVRTGEARPYANVLLRCGVFF
The following text describes a protein:
Function:
Required for the assembly of mitochondrial cytochrome c oxidase.
Subcellular Localization:
Cytoplasm.
Sequence:
MSFGRPGNLRDTFTVSPPDRGSFPLDHFHDCSSFMKTYLGCLQANQRDQSKCRVESKNYLGCRMEKGLMARVGWDELGLADVPGNGGMKDDPAL
The following text describes a protein:
Function:
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Subcellular Localization:
Cytoplasm.
Sequence:
MISIVDYGMGNLKSVENALNFLGIKSVITSEREVILNSDGIILPGVGAFPDAINNIKRDGIDKVLKEAVKKDKPLLGICLGMQLLFEESEEIKSCRGLGFLKGKIEKMKVNLKIPHMGWNNLSFCKDSPILNGIKENSYVYYVHSYCAKIEEEGILNTYSQYEIEVPGIVSKSNIYGIQFHPEKSGDIGLKILSNFGEMIK
The following text describes a protein:
Function:
Converts GTP to 7,8-dihydroneopterin triphosphate.
Sequence:
MQLLKASDIISHLQIDGIFPGGNAIPCTHLNNYMNIKEKQLMNTIADVQSSRDLRNLPINQVGIKDLRFPITLQTAEGIQSTIARLTMTVYLPAEQKGTHMSRFVALMEQHAEALDFAQLRKLTTEMVALLDSRAGKISVSFPFFRKKTAPVSGIRSLLDYDVCLTGEIKDGAYGHSMKVMIPVTSLCPCSKEISQYGAHNQRSHVTVSLTADAEVGIEEVIDYVEAQASCQLYGLLKRPDEKYVTEKAYENPKFVEDMVRDVATSLIADKRIKSFVVESENFESIHNHSAYAYIAYP
The following text describes a protein:
Function:
Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity). Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasm, perinuclear region. Cytoplasmic vesicle. Note=Perinuclear localization in excretory and germ cells. In intestinal cells, clustered signals around vacuoles with vesicles are detected.
Sequence:
MVNRKWMYIFIQFLLVSSIRSDDDVFEDDEEEVTKGSDDKEEFVPSLFVAPKLSDKSTPNFFDYFPVGSKIGLTWIKSLAKKDDVDSDIAKYNGEWSIGAPTKVSIEGDLGLIVKTKARHHAIAAKLNTPFAFDANTFVVQYDIKFEEGQECGGGYLKLLSEGAEKDLANFQDKTAYTIMFGPDKCGATGKVHLIFRYKNPINGTISEYHANQPTTIGSTYWDDHNTHLFTLVVKPTGEYSVSVDGKSLYYGNMMSDVTPALTPPKQIFDETDLKPVDWDERENIEDESAVKPDDWDENEPQSVVDEAATKPYDWNEEENELIADPEAKKPQDWDEDMDGSWEAPLIDNPACKGLSGCGTWKAPTIKNPKYKGKWIRPKISNPAFKGKWTARLIDNPNYFEPKPFAGLAPITAVGIEMWTMSENILFDNILITSSEEDSSDVAKQTFYVKQKEEYRLAAATGNGNGFFQQIIDATNEKPWLWAVYILCVLLPLVAIGVFCFGKQSKPTPNFAKKSDAYSADDDRVPNLVDDDEEEIIGDEEDDVNQPGPSGSQSNPEPQDEEENAEQQSANSSQSSAAEEEDDEHVVPENEPVKPTEEFAKKSPKNTGGAKRRTARRGD
The following text describes a protein:
Function:
Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes. Plays a role in the regulation of mRNA stability and mRNA translation to which it is bound. Involved in myogenic differentiation by regulating myog levels. Binds to a huge amount of mRNAs. Required for embryonic heart development, sarcomer and M-band formation in striated muscles.
Subcellular Localization:
Nucleus. Cytoplasm.
Domain:
The RRM domain is necessary for mRNA stability and mRNA translation regulation.
Sequence:
MHTTQKDTTYTKIFVGGLPYHTTDSSLRKYFEVFGDIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQIHPALIQRPFGIPAHYVYPHAFVQPGVVIPHVQQAAAASTSPYIDYTSAAYAQYSAAAAAAAAYDQYPYAASPATTGYVTTAGYGYAVPQPLTAAAPGTAAAAAAAFGQYQPQQLQADRMQ
The following text describes a protein:
Function:
Involved in cytokinin biosynthesis. Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP.
Sequence:
MNTFINNNNKFNKKKVVFIMGATGTEKSRLSVDLATHFRGEIINSDKMQVYKGLEIVTNKITHAEKQGVRHYLLDADYTKGIRLPIGFPEMAKYLREEKNIDGDDESKKMILQASISSIKGLDIVTNKITHAEKQGVRHYLLGGSNSYIEKLVDDPVFMFKYKYNNCFIWIDIEKSVLNRRVDTRVDEMINAGLVDEVRQIFIPDADYTKGIRRSIGVPEMASYLREEKNIDGDDESKKMILQASISSIKRNTRTLICNQLDKIQRLINEKMWSVHHIIATDVFKEDRKEVVDEAWRNTVLQPCLDIVERFLKNDDHNISIECT
The following text describes a protein:
Function:
Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism. Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism. It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein. Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism.
Subcellular Localization:
Mitochondrion.
Sequence:
MYRLMSAVTARAAAPGGLASSCGRRGVHQRAGLPPLGHGWVGGLGLGLGLALGVKLAGGLRGAAPAQSPAAPDPEASPLAEPPQEQSLAPWSPQTPAPPCSRCFARAIESSRDLLHRIKDEVGAPGIVVGVSVDGKEVWSEGLGYADVENRVPCKPETVMRIASISKSLTMVALAKLWEAGKLDLDIPVQHYVPEFPEKEYEGEKVSVTTRLLISHLSGIRHYEKDIKKVKEEKAYKALKMMKENVAFEQEKEGKSNEKNDFTKFKTEQENEAKCRNSKPGKKKNDFEQGELYLREKFENSIESLRLFKNDPLFFKPGSQFLYSTFGYTLLAAIVERASGCKYLDYMQKIFHDLDMLTTVQEENEPVIYNRARFYVYNKKKRLVNTPYVDNSYKWAGGGFLSTVGDLLKFGNAMLYGYQVGLFKNSNENLLPGYLKPETMVMMWTPVPNTEMSWDKEGKYAMAWGVVERKQTYGSCRKQRHYASHTGGAVGASSVLLVLPEELDTETINNKVPPRGIIVSIICNMQSVGLNSTALKIALEFDKDRSD
The following text describes a protein:
Function:
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for arginine/glycine-rich nuclear localization signals (rg-NLS) and PY-NLS in cargo substrates. Its predominant cargo substrate seems to be mRNA-binding proteins. Mediates docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to repeat-containing nucleoporins. The complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, GTP-Ran binding leads to release of the cargo. The importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Subcellular Localization:
Cytoplasm. Nucleus envelope.
Sequence:
MGDNPWVLQEQVLVELSEVIKNSLSENSQTRNAALNLLEKAKDIPDLNNYLTCILINATELSVSIRSAAGLLLKNNVRVSSLESGSGLQSLDYTKSTVIRGLCDPEQLIRGISGNVITTIISRWGISTWPEVLPQLMEMLSSPASTTQEGAFSALTKICEDSAQELDRDFNGTRPLDFMIPRFIELARHENPKIRTDALFCLNQFVLIQSQSLYAHIDTFLETCYALATDVSPNVRKNVCQALVYLLDVRPDKIAPSLGSIVEYMLYSTQDSDQNVALEACEFWLAIAEQPDLCSALGPYLDKIVPMLLQGMVYSDMDLLLLGNDADDYDVEDREEDIRPQHAKGKSRITLNTQGPITQQGSSNADADELEDEDEDDDEFDEDDDAFMDWNLRKCSAAALDVLSSFWKQRLLEIILPHLKQSLTSEDWKVQEAGVLAVGAIAEGCMDGMVQYLPELYPYFLSLLDSKKPLVRTITCWTLGRYSKWASCLESEEDRQKYFVPLLQGLLRMVVDNNKKVQEAGCSAFAILEEQAGPSLVPYLEPILTNLAFAFQKYQRKNVLILYDAVQTLADYVGSALNDKRYIELLITPLLQKWSMIPDDDPNLFPLFECLSSVAVALRDGFAPFAAETYARTFRILRNTLYLITTAQNDPTVDVPDRDFLVTTLDLVSGIIQALGSQVSPLLAQADPPLGQIIGICAKDEVPEVRQSAYALLGDMCMYCFDQIRPYCDALLVDMLPQMQLPLLHVSASNNAIWSAGEMALQLGKDMQQWVKPLLERLICILKSKKSNTTVLENVAITIGRLGVYNPELVAPHLELFYQPWFEIIKTVGENEEKDSAFRGFCNILACNPQALSYLLPMFVLCVAEYENPSAELRDMFQKILQGSVELFNGKASWQASPEVLAQIQAQYGV
The following text describes a protein:
Function:
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Domain:
The F-box is necessary for the interaction with ASK proteins.
Sequence:
MGLEDAGDLVLHIVLSKIGPENTARVACVSKRLKVSASEESLWSIFCSNDLNISTPLDPHGDPAPSFKRAYQLWRESFRMYPWNLVKRVRLCWDNLKQWLTLNFPEAKATLRKGVTEDDLQEFETSLKVKLPLPTRLLYRFVDGQELSSPNGLDGSLGLIGGYSAYSHDVNVYLLPLKEVMRETKESFMRDLGFSSRLDLIVMAASVVASLKIFLLDCTTGQLFTGTSNRQLLPCVPDALVRSVHDTNGDQQQDAMLLWLEEHGRRLQTGTINVRQQNNVKSISLFPEIPPLCSVSVTNGVQVRASSVFIPEISNLRDQPPAYWYAYSIRMSLMPEGCILNGTHHSSCQLYWRHWVIRADNEVIDNVNGEAVIGKYPLLQAGEEEFVYESCSSFPTTAGSIDGSFTFVPGSLRDPKGSQFEVKVVEFPLELPDYIF
The following text describes a protein:
Function:
Probable transcriptional factor. Binds to the promoter of the SQUAMOSA gene.
Subcellular Localization:
Nucleus.
Sequence:
MATHIHGMLLKNIAENNDFDEEEETEEEEEESNLKRKRLNVEKKKGSNSEGPCCQVEKCGLDLSGAKKYYKRHKLCQVHAKAPIVFVAGLRQRFCQQCSRFHEVSEFDGTKRSCRRRLAGHNERRRKTPLAIKLEDNQCRQINGEDRPQLTLTNRKASFKNYHIL
The following text describes a protein:
Function:
Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.
Sequence:
MPHIVAYKANVVHSVALGQLQVLQPGLVGVNELGKIVFVLDLSQCEASAHFDELVDLGEQLLLPGFIDGHAHAPQYSFIGVGMHLPLLQWLETYTFPYESKFQDVDYARAVYEKAVRRHLHNGTTTCSYFATVHLEACKVLTDVLEHAGQRGYVGKVNMDRNGSSGLQEDTQTSIDDTRAFVQYVQNKKNELLTPVITPRFVPSCSSKLMKALGEISREHTPKLPVQSHLGENRDEIKWVRSLHPESKTYTGVYDDHGLLHERSYMAHCIWCNKGERELLREKQTAVIHCPNSNFSLSSGVLNVRRLLQEGIKVGLGTDVSGGYSPSMLDAIRQAVIASKLVSIGNGSSSDEDSEGKQEDSLSYAEAFHLATMGSAEALGLGDKVGNFMVGKDFDALVVDPYSANSPIDEAHDPVEAADVLHTFQKFLFLGDDRNIVSIFVSGRQVKSASSELRTKKAVGVPISPLTIGSVHPSIQHLSLAED
The following text describes a protein:
Function:
Possible component of hydrogenase 4.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSYSVMFALLLLTPLLFSLLCFACRKRRLSATRTVTVLHSLGITLLLILALWVVQTAADAGEIFAAGLWLHIDGLGGLFLAILGVIGFLTGIYSIGYMRHEVAHGELSPVTLCDYYGFFHLFLFTMLLVVTSNNLIVMWAAIEATTLSSAFLVGIYGQRSSLEAAWKYIIICTVGVAFGLFGTVLVYANAASVMPQAEMAIFWSEVLKQSSLLDPTLMLLAFVFLLIGFGTKTGLFPMHAWLPDAHSEAPSPVSALLSAVLLNCALLVLIRYYIIICQAIGSDFPNRLLLIFGMLSVAVAAFFILVQRDIKRLLAYSSVENMGLVAVELGIGGPLGIFAALLHILNHSLAKTLLFCGSGNVLLKYGTRDLNVVCGMLKIMPFTAVLFGGGALALAGMPPFNIFLSEFMTITAGLARNHLLIIVLLLLLLTLVLAGLVRMAARVLMAKPPQAVNRGDLGWLTTSPMVILLVMMLAMGTHIPQPVIRILAGASTIVLSGTHDLPAQRSTWHDFLPSGTASVSEKHSER
The following text describes a protein:
Function:
Probable transporter of a GTP-driven Fe(2+) uptake system.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MITTALLGNPNVGKTSLFNQLTGSNQYVGNWAGVTVEKKEGFVNDSIKIVDLPGIYAMDTFSNEEKVSKNFLINGNVDVIIDIVDASNLDRNLYLTTQLKQFNKPIILVLNMIDVAENKGIKINYDILSKELNVKVIPIIASKGIGIDKLIETLENKTFLNYKDDNDYNFESERDAYKFIGNIIEKAVTLEYKKSISNTDKIDKIVLNPVLAYPLFLGILYIIFKFTFNWVGTPLADYIDTLLNDSLIPYLGTLLESTAPWFKSLLLDGIVAGVGSVIVFLPVILTLFLGISFLEDSGYMARAAFIMDKLMRKMGLSGKAFIPMVVGFGCSVPGIMSARTLESERDRKLTALLVPLMSCNARLPVYALFASVFFSGHETSIVFSLYILGILLAFIIGLLFKNTLFKKDEEPFIIELPEYKMPEFKNLMLHTWDKGKGFLKKAGTIIFSISVIVWLLSNFNFSGMVDINESFLASLGRVLSPIFKPLGFSGWQTSVSLLTGLMAKEVIVGTMGVIYGGDLKVTLLNHFTPLSAYSFLVFVLLYTPCVSVVATMRKEYGSRMALFSVTYQIILAWIISFLIYNVGALII
The following text describes a protein:
Function:
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes.
Subcellular Localization:
Nucleus.
Sequence:
MIDSGLFDENGNGNDHSSDDMFDGIIDIFDFPMEDVDIGGEVEELQRESSPLNDLLALPCPFSGNSCNDTSNLRTIPSDEAPRTEPIVIDTCSGNISLHGDSSDDKESLLLQNSTTSESGKSASEPFAQTIEASEGYPNFMKGKQKKKKRKKLSLLSGAMGVKKQWWQQPITIGRCMHCNVTRTPQWREGPNGPKTLCNACGVCYKRGSLFPEYRPASSPTFVPSLHTNSRRKVTEMRHKAGQEAAVGASPTFLTTPLHTNSRDKVIKMSNKAGQAGDSCSEVVEIRNKGIQVGATFLATSDSKPDEKVTEADMEASTAVSPIPVATLPSPHRKVIKMRSNGGQEAAMATTPTFVASLHSNSHKKCSFQQPVTVRKCMHCEAAQTPLWRQGPWGPKSLCNACGIRYKSGRLFPEYHPAASPTFVASLHSNSHKKVLEMRNQATQQQLSLAATDTAMSHPSQLIP
The following text describes a protein:
Function:
Catalyzes the Claisen rearrangement of chorismate to prephenate. May play some role in the pathogenicity.
Subcellular Localization:
Secreted.
Sequence:
MLASVALAALAGVGTPHATADDASPLVPLVDAAAQRLQTADPVAASKFRSGGAIDDPDREQQVIAAVTGDATRHNIDPGYVHDVFRNQIDATSSVEHTRFAQWKLDPAAAPSSAPDLSESRQKIDTLNRTMVDEIARQWPVLHSPVCRPDLDRALDAVATARGFDPVYRHALEYATHSYCR
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBC-2/UBE2L3, and then transfers it to substrates.
Subcellular Localization:
Nucleus.
Domain:
Members of the RBR family are atypical E3 ligases. They interact with the E2 conjugating enzyme UBE2L3 and function like HECT-type E3 enzymes: they bind E2s via the first RING-type zinc finger, but require an obligate trans-thiolation step during the ubiquitin transfer, requiring a conserved active site Cys residue in the second RING-type zinc finger. The active site probably forms a thioester intermediate with ubiquitin taken from the active-site cysteine of the E2 before ultimately transferring it to a Lys residue on the substrate.
Sequence:
MDDEDMSCTSGDDYAGYGDEDYYNEADVDAADDVAVTPTHSEEADYECLSVNQVERVFIDGVNSLVSRISINEKFARILLQANHWDVDKIARLVRNDRNDFLRKCHIDAKPEPKRKLSSTQSVLAKGYCSVCAMDGYTELPHLTCGHCFCEHCWKSHVESRLSEGVASRIECMESECEVYAPSEFVLSIIKNSPVIKLKYERFLLRDMVNSHPHLKFCVGNECPVIIRSTEVKPKRVTCMQCHTSFCVKCGADYHAPTSCETIKQWMTKCADDSETANYISAHTKDCPQCHSCIEKAGGCNHIQCTRCRHHFCWMCFGDWKSHGSEYYECSRYKENPSVAAEANHVKARRALEKYLHYFERFENHSKSLKMEEELRDKIRKKIDDKVNEHNGTWIDWQYLHKSVSLLTKCRYTLQYTYPFAYFLSATPRKNLFEYQQAQLEKEVEELAWAVERADGTARGALEAHMHRAEHKRQTLLHDFFF
The following text describes a protein:
Function:
Has a role in the septation initiation network (SIN) required for cytokinesis.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Localizes to the SPB prior to cytokinesis and leaves once septation is complete.
Sequence:
MYPLNANSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLLKMGRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTSYGLAADIWSLGITAIEMANGIPPRATMHPMRVIFEIPQSEPPKLDDHFSPTFRDFVSCCLDLNPNMRWSAKELLQHPFIKSAGTVKDIIPLLVQKENKLFDDSDQSVLEETINNTLKPFEEPIAEGNADIEDWTFETVKKSDSTVLGNTSIPKNSIISSQNKEELPSSIKYLEKTIMSDQATPHPFSKSLSEKGSSYHKSLTSDFAMKHYIKSTIRSMLLNDKLSATQRSSLESFYTSFISLDKNLSSKFVNQITPDNRLHHKKQKRSPISQLLFSRWLEETEKRRSLNG
The following text describes a protein:
Function:
Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MATNMYRVGDYVYVETTPNSPYLIRRIEELNKNQTGNVEAKVMCFYRRRDLPNPLVQLADKHQLATAEDSPLATKLKKTWLRTPVSEEQAAQAVLDPSIAALDEERTSPTQTSGGGGSATGNSGSNSSGTSNNNSSSTAIGGGAGGSGGAGGDAEKGEALTSKQRYQIKHRELFLSRQVESIPATQIRGKCSVTLLNETESLQSYLNKDDTFFYCLVFDPNQKTLLADKGEIRVGSRYQCDIPAKLKDTATDDRKLEELESLVWTPEHSLTDRKIDQFLVVSRSIGTFARALDCSSSVKQPSLHMSAAAASRDITLFHAMNILHKHEYSIEESMSSLVPSTGPVLCRDEIEDWSASEANLFEEALEKYGKDFNDIRQDFLPWKTLKQIIEYYYMWKTTDRYVQQKRVKAVEAELKLKQVYIPQYNNNGKGNGTSTKAGGGIYNGTTNGSTDLSSNGKPCESCGTTKSSQWNSVSSGHSTSRLCLSCWEYWRRYGSMKSATKGDAGEGDAKKKSSSAASTPTATLAGLATTPTAVVDLNDDEKISDLTNRQLHRCSIVNCGKEFKLKTHLARHYAQAHGIAISSGSPRPIMKTRTAFYLHTNPMTRVARAICRSIVKPKKAARQSAYAINAMLVKQEFTNRISGKSQAEIKKLLLLKPKDRGSVTKIANRLGAPGSGPHEWLVLTPKDKMPLPAVVSFPKPPKAPDGSLVYDRVPNKSPDVVAVPADKELTIIPTQATSTIRKRAHEDQQLNGTEVTIVPSGPPAKRPNKDPMPSHCPSPEQFAAMMAASGQPLSRHHLNGKQKIAQMARGGNGRKQVISWMDAPDDVYFRANDTHKKTRKILSAVDLRRAARKPWRTLPIKPAAPEPSSRPIESQIVILDXPSPASTLTASAASATKLLSSSASRFEQQHPPFPYTMDALLN
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
Subcellular Localization:
Chromosome, centromere. Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MASIKQPGINNQFSKKLEEMRITLLNEVLGDVSTEAELKRVHKEKMKSLKDACYKKCKDDEAMFEKMKAFLKEVEHKNAQIKERGAEIIEIKSEIQENEMQKEKMMQALQKLTEENAKKREFQVMTSQNKVNKGRLKNLNKAKQVFQESLGLEIRKLHGEKLQFVFRRVNHKDLDSVYTFTLRISEEGIYEVVSCDPPLECMSHLESRLQETNNFSAFLTNVRKEFAALPNS
The following text describes a protein:
Function:
Golgi membrane protein involved in vesicular trafficking.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MDKTKMFSAINLGVGGIFVLSGFIKLFSFSFVNALLALFIIVFGLGTIGLEKEIPPIAIKYGSFMFSFLGRGFFYAFMGTLLFSYSGFTSFLGFLVLLAGIAYCGANYVAGLQDYAPRSMRDNDWDDNVDEV
The following text describes a protein:
Function:
Catalyses the transfer of galactose onto proteins or lipids.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MTIFRKLFGRTRIFSVRCKRKVGTNRSKKCLVSITVMLFIVFVYQQRAQRFVHQVKSSALLSLNTTQSTFNLRSNTIVSNAEGPPIQPTLDLKNCSNNELVGPMAINPNITPNFDEVENASSIHLLKNGCYTPTTCIPRQKVAVIIPFKERDAHLKTLLFYLHPMLQRQKISYCIFVAEQFDDGQFNKAMIMNAAFEEAMKHDWFDCIIFHDVDMIPEDDRNLYVCGEQPRHISPAIDKFDYKSHYGTEFGGVTGITPAQYRKANGHSNQFWGWGGEDNDMEFRIFNSGMKIIPSPSKIGRYKMIVHTHPWKFSANKFPTRLNKTRVARAKTDGLSDLQYRLVGSESNPLYTKWFIDIRKIEVKRITLYIDDKPAMDIDIEPGKCRWERVEGKYLDFSIELTNIKEAAPLVER