The following text describes a protein:
Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme.
Sequence:
MADNSSSGMSSPSSLRHETHRREFKAHSADAWTQLVPYKEQVHTRSPSETIGNVYSPAAIDLKLRDLASASAKRSTDSKGPQPPKRPSSRNGSSTARVCHYPPLLNVFPDCDDCLASHSDIKPLALTDCTVSSGRPMTPGEQQEVMAATHPEPTNSDSEAEAPNAGHTEPSDEDLQRVQWYLDNAFHENQFAPLGEAMVMFDEDTNLPVTRSLYAEVDARIAFQPPPLDDQHGEPSVQAQLWDEIKADYIASMKEAILRYLLEDQSERERLQIQAMPAIHVPRTIRAPVAWHDDVVQARNACSDGINITEPMLIALGHLWHLQFHSLRCVDAAAVTEQVFQNGCFLLDDLNALIQQHCVQAQKQLRQEWTADAAEIMMALRDTWYHRVDKEDPLEAARGFQRLEHIFAAACSTMSNQLRGCIRQSLQTYLQELLEPYAGGNAYDGEYTDAHVARRPLVRMAVHVQDADVTLDPSWDEVAAAFSGHCQAIAQVAEQVPRPEKRVFPELGDREDLFIPCATADDEHVITTRERLMAIIEANKPGPARYLEMFDRFRHLLAPPNERSEEQAAVADFCAKDKPLSAYRSYIQKLQDLCREIDDLRPTAPMGLVCIDITPAQATLRERCQSLIDTLVSTVTQNNRKLNRGICERFDAIANRLMEQPQSSEDMKSLEEYLQETRAETIFKLKAEITEAGERLRFLLEFAELNEDHVKLNTTTIKWPAKLEPMFDVADRRVNEHRQAAEVQLVQRVKDFEAALETYFETAESYQNLLGIQREQQLLEQEVTPFPQIQQTQSVVEPFDKLWRTALKFFTLSEQWMNGSFLALNAEEVEEELGTLFRVAFKLAKQLTNYNGPSKTADQLRNKVEEFRVNVPIIQVICNPGMQARHWEKISDLTGYDVQPDQNTTLAQMLNLNLANHATALEDIGAAASKEFSLEKALRSMKQDWTDMEFAFVPYRDTGVSILSGIDEVQMLLDDHIVKTQTMRGSPFIKPFEEEIKEWEAKLISMQDILDEWLKVQATWLYLEPIFSSEDIMAQLPEEGRKFTIVDKSWRQIMAVSLEDSHATVCTDQPNMLSILREANGLLDDIQKGLNKYLEVKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIARLNFDDKQQIRAMISSEQEEVQFDKVLVPADAKGMVEKWLDEVGKTMISSLHKVMQQSVDAYAKAPRNQWVQDWPGQVVLAVSSIYWTMAVESAFEANRPLGEFLQQSNDQINGIVEMVRGKLPKSLRNTLSALTVIDVHARDVVAKLVDDGIQRVTDFDWIAQLRYYWEPCDESPNDNDVMVKMITTNVRYGYEYLGNSGRLVITPLTDRCYRTLMGALLLDLGGAPEGPAGTGKTETTKDLAKAVAIQCVVFNCSDGLDYKAMGKFFKGLIAAGAWACFDEFNRIELEVLSVVAQQIHSIVYAKTRRLDRFMFEGTDINLNRNCNCFITMNPGYAGRQELPDNLKVLFRTVAMMVPDYALIGEIMLYSMGFVDARALAQKIVAVYRLCSEQLSSQSHYDYGMRAVKAVLTAAGNLKLKYPQENESVLMLRSIIDVNLPKFLSHDVPLFEGITSDLFPGIELPKPDYDHISRALRENFAKHNMQATDYHMMKIIQIYEMMLVRHGFMIVGDPLSGKTVAWKVLADALADLEEAGLMDEHRVLVNIINPKSITMQELYGSFDPVSHEWSDGVLANTYRDQASSITEDRKWLLFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIAMSAQMNLIFEPQDLLVASPATVSRCGMIYLEPHKLGWEPSLESWLSDLPTSLAGDDGHAGYLRELFTWLMNPVLKFVRLQLRLFVPTSSVHLARTAIRVLDCLLDPWRSEAPPSDAQTSAQLEALFVFAITWGVGGQLVGADRPKFDEFVRAALLGNSDVVTKPKTIKLGKSSIPPERGLLHDFVFRDGSWAHWNDLIETLDIPDDATPNGIIVPTIDTVRQRFFLQQHLDHQVPILFVGPTGTGKSAIVESHLMALPKDRFVPNNITFSARTTAGQTQQIIMSKLDRRRKGVYGPPMGKHCVVFVDDLNMPQKETYGAQPPIELLRTWLDHWHWYDLKDTSRIDLVDLLLVSAMGPPGGGRNDISARFLRHLDRLGQSLVQASAAVYKAAVTNLLPTPAKSHYTFNLRDFARVVQGVMLVPASHLTESNKLVRLWVHEVYRVFYDRLVDDDDRAYLFGVVRDVTKEHFKVDSQTLFSHLVSDQAVGLQDDDLRSLFFGDFMEPGADPRVYDEVQDMDRLRETMEEYLTEYNQLSKTPMSLVMFRFAIEHVSRLARIIKQPNGHALLVGIGGSGRQSSTKLAAAMAEYTLFRIELTKTYSYSDWREDIKKMHRLSGYDGKSTVFLFSDNQIKDEAFLEDINMLLNTGDVPNLYAADEKAEIIERMGAVLKEQRRTNVDTSPLAMYNFFISRVRANLHIVLAMSPIGDEFRRRLRQLPSLINCCTIDWFRAWPEDALEMVADKFLESVELEPEVRVQVVSMCKHFHESVRALSASFYDELRRYNYVTPTSYLELIQTFKGLLDMKRNEISTLQSRYSVGVEKLDFAASQVAIMQEELVALQPELVKTSEEVAIKMKQIEADSVEVDAKKELVAADEAVAAKAAAEANAIKQECEQDLAVALPALENAIKALDTLKPSDIGEVKAMKNPPAGVKMVMEAVCVMKGVKSDRVKDPGGSGKMVEDFWGPSKRLLGDMKFLQSLKDYDKDNISPKAMKVIREKFATNEDFQPEPLKKVSAAAVGLCSWVLAMEVYDRVAKVVAPKKAKLAEAEAELAVQMAKLEEKRAELKAVTDKLQALKDELAAMVKKKEELAFNIDLCAKKLERAEQLIGGLGGERSRWTQLATDLGETYTRVTGDILLSSGVVAYLGAFTVTYRQRCIEEWSKLARRWPLMIDPQGQANKWVKNMEKNHKLAVIKLSDANFVRTLENCIQFGHPCLLENVAEQLDPILESILLKQTFKQGGVDLIRVGENVIEYSPDFRFYITTRLRNPHYLPEIAVKITLLNFMITPEGLTDQLLGIVAAEERPELEEKKNQLILESAANNRQLKEIEDKILEVLSSSEGNILEDETAIHVLSSSKTLSLEISEKQVVAETTSKEIDETRNGYVPVAEHSATLFFAIAELANIEPMYQYSLTWFTDLYRRSIRDSAKSEELAIRIHNLNDHFTYSIYRNVCRSLFEKDKLLFSFSLTVQLMARRGEIDDAEWRFLLTGGVGLDNPHPNPAPAWLSDKSWGELVRTESLPRGTFIGLREDVQQNPELFKQFYDSASPHTEPLPGPWEERLDAMQKLILLRCLRPDKIVPRVQQFVSQHMGQRYTEPPTFDLAGSYADSHSCAALIFVLSPGADPMASLLKFAEAKGFVGDSAPKTISLGQGQGPIAEQLIADAMVKGTWVVLQNCHLYTSWLPKLEYLTEEVLIPEKTHKDFRLWLTSYPTDDFPVSILQNGVKMTNEPPKGLRNNLLRSYLNDPISDPEFFGACKTPERWEKLLFALCFFHGLIQERRNFGALGWNIPYEFNESDLRISIRQMQMFLNDYEILPLPALTYLCGQCNYGGRVTDDWDRRLLGSLLGIFYSDETVTNDEYRFSPSGTYFAPAKGTYADYLSFIKGLPLIPHPEVFGLHENADITKDQKETNELFSSILLTLPRQASSGGRSANDTIDELAQDILSKVPPAFSHEEVLERFPVMYSESMNTVLAQEVVRFNRLVNVIRGSLSNVRKAIKGLVLMSGELEEVFQSMLVGRVPKLWDKVSYPSLKPLGSYISDLVERLTFLQNWIDNGTPATFWLSGFFFTQAFLTGAQQNFARKYKIPIDHLTFDFEVLSIEAEDAQTITKGPEDGVFVYGLFLEGARWDRERMQLGEQRPKVLTDALPCMHLMPVEKSKKPDRSVYVSPLYKTSARRGILSTTGHSTNYVMAVDLRTDLPPSHWINRGTALLCMLDD