lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Acylhydrolase with a broad specificity. Catalyzes the hydrolysis of phosphatidylcholine at the sn-1 position. Moderate activity toward phosphatidylcholine (PC), monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG) and triacylglycerol (TAG). May display dual sn-1/sn-2 substrate specificity. Could be involved in early wound response.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: Major isoform.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MATIPSHNLRPHTTNQRTQYSLSFRPHFSRSTLITFPARSSPARAMSRTDEEASISTRLEQESYGLTTAEDIRRRDGEAKESKRLRDTWRKIQGEDDWAGLMDPMDPVLRSELIRYGEMAQACYDAFDFDPFSRYCGSCRFTRRHLFDSLGIIDSGYEVARYLYATSNINLPNFFSKSRWSKVWSKNANWMGYVAVSDDNEATRCRLGRRDIAIAWRGTVTRLEWIADLKDFLKPVSGNGFRCPDPAVKAESGFLDLYTDKDTSCNFSKFSAREQVLTEVKRLVERYGDEEGEELSITVTGHSLGGALAVLSAYDVAEMGVNRTRKGKVIPVTAFTYGGPRVGNIRFKERIEKLGVKVLRVVNEHDVVAKSPGLFLNERAPQALMKLAGGLPWCYSHVGEMLPLDHQKSPFLKPTVDLSTAHNLEALLHLLDGYHGKGQRFVLSSGRDPALVNKASDFLKDHFMVPPYWRQDANKGMVRNTDGRWIQPDRIRADDQHAPDIHQLLTQLHHPSQLL
The following text describes a protein:
Function:
Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
Subcellular Localization:
Cytoplasm.
Sequence:
MKKKKIGLLVMAYGTPESLDDVEAYYTHIRHGRKPSEEALEDLIGRYKAIGGISPLAKITKEQAHKLTDSMNNIFTEYEFTCYLGLKHTAPFIEDAVEEMKRNGIEQTISIVLAPHYSTFSIKAYNDRAIRLSKEIGGPVIESIEQWYDEPKFISYWADQIKETFTEIDDKEKAVVIFSAHSLPEKIIAAGDPYVEQLKHTADLIAEAANIQNYTIGWQSAGNTPDPWIGPDVQDLTKDLYEEHGYESFIYCPVGFVAEHLEVLYDNDYECKVVTDELNAKYFRPNMPNAQSAFIDCLAEIVSKKVKEIVDKDLVLNNN
The following text describes a protein:
Function:
Plays an essential role in the initiation and regulation of chromosomal replication. ATP-DnaA binds to the origin of replication (oriC) to initiate formation of the DNA replication initiation complex once per cell cycle. Binds the DnaA box (a 9 base pair repeat at the origin) and separates the double-stranded (ds)DNA. Forms a right-handed helical filament on oriC DNA; dsDNA binds to the exterior of the filament while single-stranded (ss)DNA is stabiized in the filament's interior. The ATP-DnaA-oriC complex binds and stabilizes one strand of the AT-rich DNA unwinding element (DUE), permitting loading of DNA polymerase. After initiation quickly degrades to an ADP-DnaA complex that is not apt for DNA replication. Binds acidic phospholipids; The DnaA box consensus is 5'-[ATC][AT]AC[CT]TACCA[CT][CTA]-3' in this bacterium. Mutagenesis of residues that line the central pore blocks dsDNA separation.
Subcellular Localization:
Cytoplasm.
Domain:
Domain I is involved in oligomerization and binding regulators, domain II is flexibile and of varying length in different bacteria, domain III forms the AAA+ region, while domain IV binds dsDNA.
Sequence:
MKERILQEIKTRVNRKSWELWFSSFDVKSIEGNKVVFSVGNLFIKEWLEKKYYSVLSKAVKVVLGNDATFEITYEAFEPHSSYSEPLVKKRAVLLTPLNPDYTFENFVVGPGNSFAYHAALEVAKHPGRYNPLFIYGGVGLGKTHLLQSIGNYVVQNEPDLRVMYITSEKFLNDLVDSMKEGKLNEFREKYRKKVDILLIDDVQFLIGKTGVQTELFHTFNELHDSGKQIVICSDREPQKLSEFQDRLVSRFQMGLVAKLEPPDEETRKSIARKMLEIEHGELPEEVLNFVAENVDDNLRRLRGAIIKLLVYKETTGKEVDLKEAILLLKDFIKPNRVKAMDPIDELIEIVAKVTGVPREEILSNSRNVKALTARRIGMYVAKNYLKSSLRTIAEKFNRSHPVVVDSVKKVKDSLLKGNKQLKALIDEVIGEISRRALSG
The following text describes a protein:
Function:
Inositol phosphate kinase with a broad substrate specificity.
Sequence:
MVLAVVVLLGAVAVLVVVLLLQPRAPYVAVRAASLYALVYGQTRALDDVQVTVRVEARNGNAHSAAYFSRLECRLAFVGATLAVLRAYPFHVPARGVLPLAYMACAQGAPLGDAGSAAMEAALRDGMVPFRVEGEARTRWKAGDRGEHEVAFYEAFSAHAAVPTRIRDTFFPRFHGTRLLPTEAQPGEPHPHLVLDDLLAGFEVPCVADIKIGAITWPPSSPEPYIAKCLAKDRGTTSVLLGFRVSGVRVVGPEGAVWRTERPEVKAMDTVGVRRVLRRYVSSVADEGIDCALAAAVYGGKGGVLSQLRELKAWFEEQTLFHFYLDLI
The following text describes a protein:
Function:
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9. Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8 (By similarity). Required for wild-type budding of haploid sporidia and for complete symptom development during pathogenic growth such as gall formation and teliospore production in ears of mature maize.
Subcellular Localization:
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Sequence:
MSKSSTGRDERIGDFVIENEIGKGSFAVVHKGYRLQPREPVAIKIVIRKKLTPKLLDNLEGEIAILKAIHHPNIVELKECLKTEHQIYLVMAFCASGDLAQYIKKRFDIYERAGMAEPDSLTKGFKPTYPHPVDGGLNETIVRSILTQLAAALEFMRARDIVHRDIKPQNLLLQPPDAAFLALGNPREIPQMKVADFGFARHLSVNTLAETLCGSPLYMAPEILRFEKYDAKADLWSVGAVLFEMTVGKPPFRAANHVELLKRIERGEDKIKFPDERSAGSLAREAARRQELGEAPLPPPHPVSEDVKILIRQLLRQRPVSRMSFDDFFASPVISDFKAFIRPRAQPEAVERYEDLQRSERSVIIPSSGIKHVSVSSIEASTQQPGVQPPVSTATSPPALESRSTQEASPKAITGETIAPNKTPREDARPPRTLPRAFSAKYVTGEPPQPEDLEKRVPPTMTRTPSSPGIPEGSLLSGERDEAPQATTEHFGSSKGGEDSFLGKEYVLIEKQSVEVNALADELAASPQSRLGLASRRPSRLSRLSSGPLPSAPGASPPTAPPTILSSKPIRIANNTNTASTGAFALPPGSRPSSFPRRASLSSSGSPSTRQGGQVITNMDAVASTQSNRRDGNASSFPKDEVSVLGQRLAGFGLSGSGVGGGPSSALAKAISMASLRLFGVPSGVSLRDAAALVRTRAQRRGIARATDSLDEAEMTLLSTLEDLGQKAFVLSEFADSKLAHFFPDGPHQLSQELDSSTATSGISPSRNSVQGSARRVGSISSSSSSAVDPVAAEAASAEALMLYVRSLAFLQRAITLTKRHVESRSRPGVPAVTSAELNDVVQWLRARFNEVYDKADFARSRCSELPESAQQVDKLIFDKAVEVARAAATDELENNREGSGWDPSHCLLAYETANSMLSSLLDPGEDAMSLSEGSILMIDGYVKSINKRLWTLQEQFGGGVGAVGAAGASPVGVDAEARPGVSRSRTESP
The following text describes a protein:
Function:
Supplies the nucleotide substrate for thymidylate synthetase.
Sequence:
MAEVSAQDLISQLSKSPESHKRKEYLHWDDYFMATSLLSAKRSKDPVTQVGACIVDSQNRIVAIGYNGFPRNCSDDVFPWSKAKKGSQEFDPLEDKKMYVVHAEANAILNSNGMSLSGTRLYTTLFPCNECAKLIIQVGISQVLYLSDKYADKPTYRASKRMLDAVGVEYKRHIPQKKTITIDFDTFPEEDPNASLGLNELHL
The following text describes a protein:
Function:
Protein kinase that acts both on serines and on tyrosines. It acts as a dosage-dependent negative regulator of entry into mitosis (G2 to M transition). Phosphorylates and inhibits cdc2.
Subcellular Localization:
Nucleus.
Sequence:
MSSSSNTSSHRSYGLRRSQRSMNLNRATLLAPPTPSSLYDANNSTSSTSSQKPNTSFTSLFGPRKQTTSSPSFSHAAPLHPLSPPSFTHSQPQIQAQPVPRRPSLFDRPNLVSRSSSRLGDSPSLSPVAQVANPIHHTAPSPSDVRAFPIHKNASTGVKRSFFSSSMSNGAMSPPSHSPSPFLQSSQHIPPSTPAQKLRKKNNFDSFRISNSHISPFASGSFSPFATSSPNFLSTSTPAPPNSNNANPSTLFSSIPSSRHTTSNHFPSNSAQSSLFSPTARPLTARKLGFASSQTKSAVSNNHSRNSSKDASFMMKSFIPSNRSHPQTQQNESSLFSDNSMVNSSSNSFSLFPNATLPNPPSSELLTTPFQQIKPPSQVFMSTGLLSKQHRPRKNINFTPLPPSTPSKPSTFVRPHSSSTDSPPSPSTPSNTQTDSYFIQRENTPTNHNSIPTIQLEKSSMDFLRFDPPPSAVKTSHNYGLPFLSNQRCPATPTRNPFAFENTVSIHMDGRQPSPIKSRNNNQMSFAMEEEADVSQPSSSSFTLSFPSALTSSKVSSSTSHLLTRFRNVTLLGSGEFSEVFQVEDPVEKTLKYAVKKLKVKFSGPKERNRLLQEVSIQRALKGHDHIVELMDSWEHGGFLYMQVELCENGSLDRFLEEQGQLSRLDEFRVWKILVEVALGLQFIHHKNYVHLDLKPANVMITFEGTLKIGDFGMASVWPVPRGMEREGDCEYIAPEVLANHLYDKPADIFSLGITVFEAAANIVLPDNGQSWQKLRSGDLSDAPRLSSTDNGSSLTSSSRETPANSIIGQGGLDRVVEWMLSPEPRNRPTIDQILATDEVCWVEMRRKAGAIIYEGIHGSSSNPQGDQMMEDWQVNV
The following text describes a protein:
Function:
Transcription activator that regulates the expression of at least NAI2, PYK10 and PBP1. Required for and mediates the formation of endoplasmic reticulum bodies (ER bodies). Involved in the symbiotic interactions with the endophytes of the Sebacinaceae fungus family, such as Piriformospora indica and Sebacina.
Subcellular Localization:
Nucleus.
Sequence:
MDDSSFMDLMIDTDEYLIDDWESDFPICGETNTNPGSESGSGTGFELLAERPTKQMKTNNNMNSTSSSPSSSSSSGSRTSQVISFGSPDTKTNPVETSLNFSNQVSMDQKVGSKRKDCVNNGGRREPHLLKEHVLAERKRRQKLNERLIALSALLPGLKKTDKATVLEDAIKHLKQLQERVKKLEEERVVTKKMDQSIILVKRSQVYLDDDSSSYSSTCSAASPLSSSSDEVSIFKQTMPMIEARVSDRDLLIRVHCEKNKGCMIKILSSLEKFRLEVVNSFTLPFGNSTLVITILTKMDNKFSRPVEEVVKNIRVALAE
The following text describes a protein:
Function:
Component of the mitochondrial respiratory complex IV (CIV, also named cytochrome c oxidase complex), the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The CIV complex is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Acts as an assembly factor that specifically drives the homodimerization of CIV complexes, mediating the formation of mitochondrial respiratory supercomplexes (respirasomes) containing two CIV: supercomplxes with two molecules of CIV show improved activity. Despite being highly expressed in brown adipose tissue, not required for thermogenesis.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MRGLMISRSGALLRAFSSSARRSIENRVPEKQKLFQQDNGLPVHLKGGTRDALLYRLTMLLSVGGTCYSLYCLAWASYPHKKE
The following text describes a protein:
Function:
Functions as an E3 ubiquitin ligase.
Sequence:
MSEEEEEIYNKLRSANTVDHEQGLILLRKTTRSSESSRISLCTERLLSLLRSLLVSRYNIVQTNAAASLVNLSLEKPNKLKIVRSGFVPLLIDVLKSGSTEAQEHVIGALFSLAVEEENKMVIGVLGAVEPLLHALRSSESERARQDAALALYHLSLIPNNRTRLVRAGAVPIMLSMLRSGESASRILLLLCNLAACSEGKGAMLDGNAVAILVGKLREGGADSEAARENCVGALLTLSVGNMRFRGLASEAGAEAIMTDIVESEGGSERLKEKAGKILQAIRGGEREFGEGAEAREWNRMLEASGLSRSQFQGGQKEGFAYSSQF
The following text describes a protein:
Function:
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not bind mammalian glycans. Probably plays a role in the defense system against microorganisms. May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (By similarity).
Miscellaneous:
MISCELLANEOUS: Constitutive expression does not lead to enhanced immunity to N.brasiliensis or M.tuberculosis.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Enriched in lipid rafts.
Sequence:
MTQLGFLLFIMVATRGCSAAEENLDTNRWGNSFFSSLPRSCKEIKQEHTKAQDGLYFLRTKNGVIYQTFCDMTTAGGGWTLVASVHENNMRGKCTVGDRWSSQQGNRADYPEGDGNWANYNTFGSAEAATSDDYKNPGYFDIQAENLGIWHVPNKSPLHNWRKSSLLRYRTFTGFLQHLGHNLFGLYKKYPVKYGEGKCWTDNGPALPVVYDFGDARKTASYYSPSGQREFTAGYVQFRVFNNERAASALCAGVRVTGCNTEHHCIGGGGFFPEGNPVQCGDFASFDWDGYGTHNGYSSSRKITEAAVLLFYR
The following text describes a protein:
Function:
Functions as a substrate-specific channel for nucleosides and deoxynucleosides. Has a greater affinity for deoxynucleosides than for nucleosides, and does not transport free bases. In addition, constitutes the receptor for colicin K and phage T6; (Microbial infection) Serves as a receptor for CdiA-STECO31, required for adhesion between E.coli expressing CdiA-STECO31 and this strain.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEIEPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMSLSMNVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLGDDSGNAINGIKTRTNNSIASSHILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGNFNVRSTGWGGYLVVGYNF
The following text describes a protein:
Function:
Part of a complex that plays a role in tracheal liquid clearance. In both larvae and adults, contributes to the behavioral response to salt. Probable role in sodium transport.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MLLYTKELVIPRPRPGLLRFRNNPRGIKFREKLCNSFAHSNIHGMQHVFGEQHLWQRCLWLAIVLGAVITGFSLYTVLMHRHSEQLLVSLIETTQLPVYHIDFPAVAVCPWNHFNWQRAPSAFIRFLPRHPNAELRETFRQLLASMDIMNFSNFNRIRILTKRNLTGISYLKMTDLMNFMTYRCDELFVADSCVFDETPYDCCKLFVREQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFTINASYSFMNNIDALTPFGMNLMIKEPRQWSNEMMYHLYPDTENFVAVHPLVTETSPNTYEMSPKKRRCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPECGINDAQCLGNNSDIFTYVKMGDQEKYINDSRQGHFCDCPDNCNSRLYEMSLNVRKLDYPKNSTDQLIKAQVYYGQRVMTKIITKLKYTNIDLLANFGGIISLYIGASVMSFIELLFVLGKLMWGFIRDARIKLKEYTK
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MTIPLPSLRYTVQSVPANLLQFTNPTSTNESQEPKENVLWIGCSDSSVTETYVLNNVSRSEIFVHRNLGNRVSVGDTSSGSAIEWAVDVLKVQHIIICSHYDCHLLEESESDSNNWYRDIIQLHQESDALEPPAQSPQSRNRHFTELYVLSEVEWLKQQPSVQRAMKEWDCKVHAFVYDRAQNSCVRLVPESQQK
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MASRKHESLFFASASDSNPDWIKNEYSSELKKNIDLQQTVHRTENPCEIYTKYSATSVHLPVGQRSNKLNPVCFSIHKCSVCGKQFSRKSDLTVHKRIHTGERPYKCSYCGKGFCQASMVRRHERTHTGEKPYQCSDCDKSFSRSTSLLIHRSRHTGERSLRCDCGRTFINKAFLQRHRKTHMYQPHPCNICGEVFKNQLGLRVHKRSQHSEKSYNCSECGKCFVQIHLLKKHLKKHADECPKVFRTKTREDTADSFSIQQTSLWHLGEKKLKPEEENIPLDCSASPRNSVCLECGKTCSNPTSLQKHQLFHGQGSLICAECGKTFVRKSDLTVHLRIHSGERPYSCSYCGKCFCQASMLRRHERTHTGEKPYQCSECDKSFARSTSLLIHRIAHIKDKPFKCKSCAMTFSNTTQLRQHTKTHRSSIKVPCDMCNNSCGQAHTCSLHGSGQLSEDPFLCSDCGRTFNSDLGLQRHLLTHAQQPFPCKICGVVLNSRFDFRIHQRSHPPDRPFICSHCGKNFPRLNLLRIHQNTHTGSRPYECSFCKKTFSDPSTLRQHRQRHQGVKPSLFKDKALPVNQESSNPTIKTHGCPSVCPECGKTFSNPSALQKHQQSHEKESLLCAECGKNFSRKSDLTVHLRIHTGERPYKCSYCGKDFCQASMARRHERTHTGEKPYQCSDCEKCFSRSSSLLIHRSKHIDAKPFKCVSCEQTFSNAGQLHVHLKTHEENVNNPLKNNLPNEKRQVH
The following text describes a protein:
Function:
Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
Sequence:
MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVVEKLDKLIDYPRAIGIDDEALRTMQSVGLVDDVLPHTTPWHAMRFLTPKGRCFADIQPMTDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCLFSRELEAFSQQDDEVTLHLKTAEGQREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDPVRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYTHNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDALLDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMRFKPMPQYYGGALMREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCNPLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNASLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA
The following text describes a protein:
Function:
Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2.
Sequence:
MSHPAQDLLIIFEDEAEQWATYLKSVFLKSTREENICFYNIGTVSIRKEEFLQLSQYKCKLLILTKGMLDGLCQIRKFFLARVLQPSKSVVILLCGVDSLSSLFDMVPIGSDCFQISSDQDSKEYLTIVTQILQGTQSSLQSSSLSGRAAGKEVKLIKKYSSESPPVGSSVVVLPTRIPCEKPGELFILLQDVAVPKDTVVEFHGNEQKIKVQPTLWNEKTLCVKALAFPPGTVNVTVYNRGTVTGKTQVQYYNTMGEIAVLLKKAADPINFMWQAFQISSTEKLDQLLSSSLRQRMPTGGFGVLQLDESNKGSEHSDDLPTLLHFAAKNGLKNLASLLLQCPGAYQAIKMMNKDGDNPLKLAEKHGHTEMQKHMQETLDMTQSSRNEENEDSNICGLTGLDPANHEKNNNGDDIQQKTEEENVHEDEDEDEDPYAPLGGNDEEYDTILVSNKSMSIINRPPAPTPRPDASPVKEDSTPFIAQVFQKKMSQADTGSLYSISSRQGKERDNISSTYDSFAPYQHSGLEELIELQEKVKRGSLTMDEALDRFNEWQKMQKGLDALQQVKLQQLRASIINNREDDDNVYDKINIIHHTPVGMSDSGQGSQTAEQDFYSKPFKGHQSHFFGKSDKR
The following text describes a protein:
Function:
RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MALNRSMHPRNRYKDKPPDFAYLASKYPEFRQHVHTNLTGRVGLNFKDPEAVRALTCTLLKEDFGLTIEIPLERLIPTVPLRLNYIHWVEDLIGGGSPHRGIDIGTGASCIYPLLGATMNGWYFLATEVDDICYNYAKKNVEQNNLSDLIKVVKVPQKTLLMDALKEETAIVYDFCMCNPPFFANQLEAKGVNSRNARRPPPSSVNTGGVTEIMAEGGELEFVKRIIHDSLQLKRRLRWYSCMLGKKCSLAPLKEELKKQGVPKVTHTEFCQGRTMRWALAWSFCDDVAVPSPPSKKRKLEKARKPITFTVLGPTVRELAAKASSLGSPARGSTDTVTAWIEKTLADLRVLHKRVPCGKSELSLFLTAVENSWIHLRHKRRDRGRQLRELPRAPLEGVGGMAQTPDNPQPAAQSTNSQANPETSARGSEVIGAGNSEEAGVGTCQDCPLPDKNGSSSDRKSSTAEQEKDAAVAQLDVQDSGLDTGAIGVSPGAAGTQEAANASVTAGNSGGPSGVQHFLFKCLMNVKEEGGDVTVEMHWVEGQNRDLMNQLCTYLKNQLFRLVANPV
The following text describes a protein:
Function:
Monoterpene synthase catalyzing the production of beta-phellandrene from neryl diphosphate. Also produces lower amounts of delta-2-carene, alpha-phellandrene and limonene. When incubated in vitro with geranyl diphosphate, catalyzes the formation of acyclic myrcene and ocimene as major products in addition to beta-phellandrene.
Subcellular Localization:
Plastid, chloroplast.
Domain:
The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
Sequence:
MIVGYRSTIITLSHPKLGNGKTISSNAIFQRSCRVRCSHSTTSSMNGFEDARDRIRESFGKLELSPSSYDTAWVAMVPSRHSLNEPCFPQCLDWIIENQREDGSWGLNPTHPLLLKDSLSSTLACLLALTKWRVGDEQIKRGLGFIETYGWAVDNKDQISPLGFEVIFSSMIKSAEKLDLNLPLNLHLVNLVKCKRDSTIKRNVEYMGEGVGELCDWKEMIKLHQRQNGSLFDSPATTAAALIYHQHDQKCYQYLNSIFQQHKNWVPTMYPTKVHSLLCLVDTLQNLGVHRHFKSEIKKALDEIYRLWQQKNEQIFSNVTHCAMAFRLLRMSYYDVSSDELAEFVDEEHFFATNGKYKSHVEILELHKASQLAIDHEKDDILDKINNWTRAFMEQKLLNNGFIDRMSKKEVELALRKFYTTSHLAENRRYIKSYEENNFKILKAAYRSPNINNKDLLAFSIHDFELCQAQHREELQQLKRWFEDYRLDQLGLAERYIHASYLFGVTVIPEPELSDARLMYAKYVMLLTIVDDHFESFASKDECFNIIELVERWDDYASVGYKSEKVKVFFSVFYKSIEELATIAEIKQGRSVKNHLINLWLELMKLMLMERVEWCSGKTIPSIEEYLYVTSITFCAKLIPLSTQYFLGIKISKDLLESDEICGLWNCSGRVMRILNDLQDSKREQKEVSINLVTLLMKSMSEEEAIMKIKEILEMNRRELLKMVLVQKKGSQLPQLCKDIFWRTSKWAHFTYSQTDGYRIAEEMKNHIDEVFYKPLNH
The following text describes a protein:
Function:
Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.
Sequence:
MQRPVKFGRIEYDVEEHKVLQSTLRKDLAPEMVSQRHGPGGQKLAYIEGWRLIALANEVFGFNGWSHQVVQQTIVCGLDCVDQVDDKFYVGVSSTVRVELKDGSFHEDIGYGVCEGMKSKALSLEKARKEAATDGLKRALKGFGNVLGNCLNNKNYLRWANKYPVTTPAPPQKNETVLEVPPAVHRSRYNAMEEKKRGIEALKTPSAASTSVPIIEKNVDATHESTHPMPAPQEPAPQCPGLPTGQKLISTKETALTSIKPPNISGAQNGETINNSALKDDLLNESDPVKLERKRKQQQKKEEFLQQLKRQKQEDGARISTVSIKSEQTSPVPEDDSEKWMREVDPESFALISGIDWSDEENPAPYQAIINKPNVNTVTKPAPHKPAPHKPAPHKPALAVPKANNFRK
The following text describes a protein:
Function:
E3 ubiquitin protein ligase that regulates leaf senescence through ubiquitination and subsequent degradation of WRKY53.
Subcellular Localization:
Cytoplasm.
Sequence:
MTLSRSSADDSTNNANRSYSAVAGTDNKRKRDEDSSDYVGVAESLEMLKKQEIDADHMAASAQQTLISWRSGENSRSLSSSGECSSSNRPESTRLQIFVRMMSGGKTIVIHAEKYDTVEKLHQRIEWKTKIPALEQRVIYKGKQLQRENSLTYYSIEQDASLQLVARMQSTEHPVAWQTIDDIMYTISRMYKGENLQSNINEKIVTFFAMIPVESDESIAKYLNIFSNSSVPAALVMLYASSLERNKSCAKSSVKLFLSNCVALPKNQKNYCLPIVLEFCKLLRKVCPDQKLYVTCRNTLGSMLETFDNPHGVYNDQYETFGVEIFPFFTELTGLLLNELAQNSGPSFCDFQKVSSFWQQLRKVIELKVAFPIPIVLPMQSTALEAEIRHLHRLFGSLLTTMDLCMCRVESSLADKEVGNSETMSSSWSQYLSILKIINSMSNIYQGAKGQLAVMLNKNKVSFSALVVKFAKRGDDHQWIFEYKEATNFEARRHLAMLLFPDVKEDFEEMHEMLIDRSNLLSESFEYIVGASPEALHGGLFMEFKNEEATGPGVLREWFYLVCQEIFNPKNTLFLRSADDFRRFSPNPASKVDPLHPDFFEFTGRVIALALMHKVQVGVLFDRVFFLQLAGLKISLEDIKDTDRIMYNSCKQILEMDPEFFDSNAGLGLTFVLETEELGKRDTIELCPDGKLKAVNSKNRKQYVDLLIERRFATPILEQVKQFSRGFTDMLSHSVPPRSFFKRLYLEDLDGMLRGGENPISIDDWKAHTEYNGFKETDRQIDWFWKILKKMTEEEQRSILFFWTSNKFVPVEGFRGLSSKLYIYRLYEANDRLPLSHTCFYRLCIPRYPTITLMEQRLRLIAQDHVSSSFGKW
The following text describes a protein:
Function:
Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP) utilizing UTP and therefore links the biosynthesis of TPP to pyrimidines metabolism. By producing thiamine pyrophosphate, a cofactor of the mitochondrial pyruvate dehydrogenase indirectly regulates pyruvate oxidation and lipogenesis. Although it can also catalyze thiamine phosphorylation using ATP and CTP in vitro, it does so with significantly lower efficiency and without physiological relevance evidence.
Sequence:
MEPLQFLLPEKYQKFALLILNCPFGKVKKFLPILWRKAVFTVCVDGAANHLHTHFFSDIDSVFSEYELDFVPDFITGDFDSINKHVLEDLSARGSQIIETPDQDHTDFTKALKFVLSRSNIDSLLDSVVVLCGLPTESRFDQVFANLNTLMIASKISDKPVWFIYGESMSVLIQPGKHTINVQSGLEGDWCSLVPIGRPCTDVTTSGLKWNLEHSTLEFGSLISTSNMLDGTGLVNIETNETLLWTIGIKSCLESPFWAPSY
The following text describes a protein:
Function:
May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli.
Miscellaneous:
MISCELLANEOUS: Present with 1970 molecules/cell in log phase SD medium.
Sequence:
MFSLSSLSSSGGHSEQKERERISYFDIRINSPYKDIILIQGSPLELSSIPLSGNLVISVKNEIVVKKISLRLVGRFKLEFLQVGRYKKNSSSLASLVKEKRKIFECYWDNLLVSSKGDVLVGGENAENQHNSSSGRSTSNQDMDTSGNAIFLSKRSLSSPVFNKIIRRKTHSSHRKILELPENGVTGTPFEGLRENARSRSSSSNTLNNNSHSYSNRDGSGSSYLFLMKRGNYELPFNTMLPPEVCETIEGLQSGSILYSFEAIIDGRQLWDTDLSVHTSPHGPIGSTSTSGNGMRTKNKIIIKKFKYLRILRTLSMDNLAMQEEISVGNTWRDKLQYETSIPSRAVPIGSTTPVKIKIFPFEKNIRLDRIEMALIQYYAMKDSSAQIYDDEIAVMKITHLADFGPLTDKLDVDCPFTIPDNLKQITQDCCLQDNLIRVMHKLQVRILLQRQVDGEYKNLEIKAQLPMLLFISPHLPMKGRLVLFDKHDGKIHFRPGELVPLFLTTYPAQGLTPGVELNSTTTAHLALPQPPPNYHESTNDHLMPALQPLGADSVVLTVPSYEQAQAQASASSYVTGSVPAYCDDD
The following text describes a protein:
Function:
Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as a tumor suppressor.
Miscellaneous:
MISCELLANEOUS: Defects in LZTS1 are found in many types of tumors.
Subcellular Localization:
Cytoplasm. Cell membrane. Cell projection, dendritic spine. Postsynaptic density. Synapse. Note=Associated with the plasma membrane and with microtubules. Detected in dendritic spines, especially in the postsynaptic density (By similarity).
Sequence:
MGSVSSLISGHSFHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGHGKSSSKMGKSEDFFYIKVSQKARGSHHPDYTALSSGDLGGQAGVDFDPSTPPKLMPFSNQLEMGSEKGAVRPTAFKPVLPRSGAILHSSPESASHQLHPAPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTSSSYQLDPLVTPVGPTSRFGGSAHNITQGIVLQDSNMMSLKALSFSDGGSKLGHSNKADKGPSCVRSPISTDECSIQELEQKLLEREGALQKLQRSFEEKELASSLAYEERPRRCRDELEGPEPKGGNKLKQASQKSQRAQQVLHLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTSFGPALEETQWEVCQKSGEISLLKQQLKESQTEVNAKASEILGLKAQLKDTRGKLEGLELRTQDLEGALRTKGLELEVCENELQRKKNEAELLREKVNLLEQELQELRAQAALARDMGPPTFPEDVPALQRELERLRAELREERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYVAMYQRNQRLEKALQQLARGDSAGEPLEVDLEGADIPYEDIIATEI
The following text describes a protein:
Function:
Acts as a transcriptional activator of the phytosulfokine PSK5 peptide hormone. Binds to the GCC-box pathogenesis-related promoter element. Rate-limiting factor of quiescent center cell division active when surrounding stem cells are damaged. Is a proteolytic target of APC/C-FZR1 complex.
Subcellular Localization:
Nucleus.
Sequence:
MANSGNYGKRPFRGDESDEKKEADDDENIFPFFSARSQYDMRAMVSALTQVIGNQSSSHDNNQHQPVVYNQQDPNPPAPPTQDQGLLRKRHYRGVRQRPWGKWAAEIRDPQKAARVWLGTFETAEAAALAYDNAALKFKGSKAKLNFPERAQLASNTSTTTGPPNYYSSNNQIYYSNPQTNPQTIPYFNQYYYNQYLHQGGNSNDALSYSLAGGETGGSMYNHQTLSTTNSSSSGGSSRQQDDEQDYARYLRFGDSSPPNSGF