lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Transcriptional activator required for growth on non-fermentable carbon sources and that regulates genes involved in fatty acid utilization. Acts as a direct activator that binds the promoters of oleate utilizing genes, encoded key enzymes in beta-oxidation and NADPH regeneration (POX1, FOX2,POT1 and IDP2), the glyoxylate shunt (MLS1 and ICL1), and gluconeogenesis (PCK1 and FBP1). Also regulates the abundance of peroxisomes that are vital for fatty acid oxidation.
Subcellular Localization:
Nucleus.
Sequence:
MAAKRGLAKQKSRVTKACDRCHRKKIKCNSKKPCFGCIGSQSKCTYRNQFREPIEAFFNYTGSLSNDLDNAKCSIAKLKAQLPPSAPASLQKGLANICTELEKIQPQLYLNLDSKEISSYGGLKSIETEIIGKQSKSLNRFSNAFESNTAQNVSMYFGVYSPLLYFASTGISWITKKLISCSNDRETRETIYLFLKFLDASSASHAGPKVTSISPLEYYSKLNGLSCGNDVLIQHIMSNISNEIKGNTNINQTIKFNKPTDWFMYGVQLMEQHHKALDRKSSKKLLPLKYFLEQDELIFCLCLEYFERSLFSTMYDLTILKGLVSLMKHRYWIDDPFVLGRIISTMSRRSLDAGLNRWEYYIGQDEDTAEEYRKLWWDCYWWDRWYSLVTGKQPLIPHEMTSCLFPKDVVGLGVDDSMDCFTLINLVELDPSKFDICISFGYILLTKIITAVFSGLLYNRHFTDYRLFATPNAKDLNGTARQLMVEFSKICKIFQCIQDKLIPFLKQYSENSNVFELYTHFGFAKVCCFQGMESLILRIQNLLQERERIELDSCVKDIRLQTFEASVDILTDVLKHEDTFYIFRCSWFIYAILMNITLNFIETPRRNSICYLSLMCRMIASYNDLFVSSGNVNFKGNNAFSKKLENGTAVSFILTRICCQMYTRSQKMAKESLFCELKKYGQACSDAGQAALDIECIWYRNIIGEHKESSFRKEILSILDREMGDLVNNRVIGVQGKNQEGACYEKLSPSSTSVSVGMDFCSLENFVTAESLPDLLNLFWEDTEFGITKENLGE
The following text describes a protein:
Function:
Degrades free oligosaccharides in the vacuole.
Subcellular Localization:
Cytoplasm. Vacuole.
Sequence:
MTLFPVLNNTPVGKQVDSIYESRLDQFLSEGQYRDFNLPSVYDHARIDNPSGDVNNDLSKGFVDLKVYRVPDLSRPSFNEVVGHKKFDETASKGDTFGPSWATFWFEVHIRLPKSWAKYEQVIFQWNCDNEGLVYSQDGVPLQAFSGSERTDFILPDSWKTTEDTFYIEMACNGMFGTGAGSQIAPPDPNRYFTLTKADLVAPNLPAMALAYDFLLMQQCVKQLPSNCWQKYKARQICNDIMNTFHPNDLSTINECRNLAKAFLGNDIDSEAVFEKNNDKANVFAIGHCHIDTAWLWPFAETRRKIVRSWATQMNIMDRYPEYQFVCSQALQYLWLKEDHPDVFEKLKEYVNQNKFIPIGGSWVEHDTNIPNGESLIRQFLLGQHFFEKEFGVRCRTFWLPDTFGYSSQIPQICRLCGMDRFLTQKLSWNNINSFPTSTFNWVALDGSQVICHMPPANTYTADTNVNDVLHSIDQHKNLVNDQAGLLVFGIGDGGGGPTPEMLEKLRRCKGIANTVGYLPNVKLGNTVDEFFDGILKRTNAGQTLPSWNGELYFEFHRGTYTTQAELKKLMRKVEIALHDAEYVSTLASIFSKDYSYPKESLQDLWRDTLLCQFHDVLPGSCIEMVYKDAIPIMSKVLKNTEALLWQAIEQLGFKKASSSDNKEQLCLLNTLPWNVRGVITETEENKLVYFESCDGKGILTAAHTSLKHPAAAYQKDDNFILVNDHLRVTIAPNGLILSLFDLHKEREILDLKSGKNHAGANQYVLFEDTPLSWQAWDTEVFSLEKYEVLDKGKVSIKESGPLRASVVVDIPISELSHMKATISLEGYNDCSEFTGVNFTCEVDWHESCKFLKVEFPVDIHSEFASYETQFGITKRPTHYNTSWDVAKFEVCHQKFADYSDFTYGVSVLNDCKYGFSTHGNLMRLSLLRSPKQPDAHADMGKHTIRYAVYPHSKPLDSSTVRAAHKFNSNFRLLTRASDTANLDIFDAFQLVGEPNVILSHIKMAEKGKSIILRVYESLGGKSRARLVIKSLTVASVTKCNGLEEDLEELCTLKSNDYYEVPIELRAFEIATFKVNL
The following text describes a protein:
Function:
Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa.
Subcellular Localization:
Cell junction, adherens junction. Cell membrane; Single-pass type I membrane protein.
Sequence:
MDTTAAAALPAFVALLLLSPWPLLGSAQGQFSAGGCTFDDGPGACDYHQDLYDDFEWVHVSAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNPGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIATGRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRGHNESKADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLDPNGIITQYEISYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPTLPDYEGVDASLNETATTITVLLRPAQAKGAPISAYQIVVEELHPHRTKREAGAMECYQVPVTYQNAMSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAATEEPEVIPDPAKQTDRVVKIAGISAGILVFILLLLVVILIVKKSKLAKKRKDAMGNTRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDQHNFSPRYENHSATAESSRLLDVPRYLCEGTESPYQTGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS
The following text describes a protein:
Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, axon. Cytoplasmic vesicle. Membrane, caveola. Presynapse.
Sequence:
MLEKSYSLFLLQVISLQNSGLNMDMLDKENFVNITKSSLIEINHDRRFYRSDMLATGVNTSEILNWTMASENLTHLTTEGSKFSLEKNWPALLTVIVIVVTIAGNILVIMAVSLEKKLQNATNYFLMSLAITDMLLGFLVMPVSMLNILNDYEWPLHRKLCPVWISLDVLFSTASIMHLCAISLDRYIAIRNPIHHSRFNSRTKAFAKIIAVWTISVGISMPVPVFGLQDDSKVFDQENCSLSDENFIIIGSFVAFFIPLIIMVITYFLTIKSLQKEATLCINNLGAKSKLALFSFLPQSSISSEKLFQRSLQKELAPYGRKTMQSISNEQKASKVLGIVFFLFVIMWCPFFITNVMAVFCKESCNEHIIGELLNVFVWIGYLSSAVNPLVYTLFNQTYRSAFSRYIQCRYREEKKPLQLILVNTIPALAYNSGQLQLAQMKSLKKEGKMKTNDYSLVTIGLQSLDKASKSGVAPLNENVSCL
The following text describes a protein:
Function:
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.
Sequence:
MVEHSVLSYAGYYYGKECGYCEEKNKNEQFGLFGNALTSEAYQILIDRGWRRSGKYLYKPNLRNSCCRMYTIRLDATQFKPSKEVKKSLKKWKRFLLGDKLYQKVYANKPFQLDDYIGSNALDKSLDDDKVIHKLTVELEPSSFSKRKFELYKKYQKAIHHDKEEELTEEGFVRFLCDSPLEEVCDSDIDEDELSDDENNHPLYGSFHQLYSVDDELVAVGVIDLLPHAVSSVYFFYDPDYKGYSLGKLSATYETVMAKRMGYQYYYMGYYIHTCQKMKYKGRYGPSYLLNPTTCTWLPLSKFVDCWENGAPRYIFFDEQGQMQTAAEMSRENVQKDDLMQSFKRKMPGIESEEAARKAIDDNPGGYAYGMLFPAKGLCTSLAKMEDVFMEVNATVGLELAKTYVLQL
The following text describes a protein:
Function:
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
Sequence:
MIAGVVTARNPGEALEKIKTSKFNLYEVRLDSFESFEGLEVLGEYSKKLIFTPRRREEGGIRPLDDGTRLSLYRRVMELKPAYVDVEFASDIAQEVMELAKEKGVGVILSYHDFNGTPDFGKLLTLLEDMEELEPEIIKIVTTANSPLDNLRVLRLYEHAENLIAFCMGPLGRISRVFSAQLAPFTYAPLEGEVAPGQLRAEELDRLRVMLFG
The following text describes a protein:
Function:
Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Also has endonuclease activity toward 5'-flaps.
Sequence:
MHEQYQAPLPVNSPALPEPFYYLHNFRAVLAWIGERYADLLDDQERAFIAAFAELPEASQALLVRMVMRKGTLFREGKLAYAEIGDTRAAVQPLLALGWVDAQPTLELAQLFGLLKKDELSQLFRDHLGRANLRKDALLERLQPLFPEARRLAEWQADFAEPVYELRCMALCDRLRLMYFGNLWQDWSEFVLADLGIYRYESVEFSADSRGFRLRADVDAYLHLFDCRQRFDLGEPLEELLAGLPGEPYANPWLEGRRVKLLFQFAQHCEKQRDFDLAQRLYRQSSHPGARLRAIRSLERGERFAEAHALAREASCAPESDAERQGLARLLPRLQGKLGLPRQARAAAPEIDRLDLCLAFPSEPCSVEWAVREHLEEPGCAVHYVENGLINSLFGLLCWEAIFAAIPGAFFHPFHSAPADLHSADFRQRRAALFEACLGRLEDGSYRDAIRCRYRDKFGLQSPFVYWELLGEELLEQALDCLPAAHLRAWFERLLEDIPGNRAGLPDLIQFWPAQRRYRMVEVKGPGDRLQDNQLRWLQFCREREMPVAVCYVRWHVDD
The following text describes a protein:
Function:
Responsible for the cyclization of trans,trans-farnesyl diphosphate (FPP) to (+)-delta cadinene.
Sequence:
MEAKVIERRSAGHLPTVWDVELVKSFTTPYSFESHGSRLEELKQGARDLLATMKEPRDQLDLINTLQRLGVAYHFEKDIKDILAKLVDANIATDLYTVALQFRLIRQNGFFISTDVFNKFMERDGKFMDSLREDVFGLLSLYEASYLGMPEEDVLDEALNFSIKHLLMLRKKMDGNKAEQIQQSLEYPLHWRMPWTEARDFIAINRYDAKMNSVLLELATLNYNIMQSVYLKELQELMEWWKDLNLKERLPFARDRLLECYFWGLGSCPPGPQLPMLRRNLGKFGSLATPLDDIFDVYGSLDELEKYTDAVNTWDLSKAMEELPEYMKVSFSAMYNHVSEMVQDALKDNGMDILPSIKEQWLCYVRGYLKEARWFHSGYTPTADEYLENAWVSSGIPLSIVYGVFGVAGHSINQYLSEFVEHWSASDLIRLPACISRLIDDLNTAEVEMKRGESMNFIHFYMTQEGVSEEEARDHVKGLIRNLWKKLNKAIVKDSVRAPGIVKVAVEMTRCVHRIYHYGDWFGIQSKENQDCVKSILEPIPMEQCDQALLK
The following text describes a protein:
Function:
Part of the ABC transporter complex FbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. Probably responsible for the translocation of the substrate across the membrane (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MGWASFNLTWAWFLPVIVYGALPLLRLPQQTQAKTELFLTALSVLFMFISATVYKISMGYSVIVLLVGYTALATLSLAKLKVMQGDKFIIASLLCIILLIFFFIVYPTLAIFVSMFYDGDTFAPQQVMRILTQSYIVRVITNSLFLSGFVGIVSTVFGLAFALYTTRIARRTAFIGKIFSILPIVTPPFVVGLGVTLMLGRSGYVTEFLSTNFGFSSHNWLYGFNGIAIAQILAFAPISFMILDGALKSVHPSIEEASYTLRANRYQTFYQIIFPLLRPALANSFLIVFIQSLADFSNPLVLGGSFDVIATQIYFYIAGSQLDYASASTLGSMLLIFSLAIFIIQYIWIGNRSYVTVSGKSYRGDVQELPNGLKYTIIGMLGFWVIFNMALYGSIFYGSFTVNWGVNYTLTLKNYAMLFGQGLSDGAWPSLINTLIYAGIAAPLTAFFGLLIAYIVVRKDFQGKKSLEFLTMLCFAVPGTVAGVSYILAFNNAPLYITGTGIIVIISMVMRDLPIGMRAAIAGLGQLDKSLDEASLSLKGSSWKTLCFIVLPLLKPALLSALVTSFVRAMTTVSAIIFLVTADTRVYRIYFKSCGRRRIRHCDCIRFYFNCCDDGNYFVFRLDCRRYAYFPF
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MTVDLNIPYSACELKRVKRLELGVLDPEIIKKISVCEIVNVDIYKDGFPREGGLNDIRMGTIDYRTLCGTCNMNVKYCPGHFGHIELAKPMYHYGFMNVVLNVLRCVCYHCGRLLCNVNSSKVKYIEKIKVNSLRLRKLAELCLGIRACDHSVEEEGLNINDNSLNNFYNNDLSNLNMNQQMLLNKSNYTNIFEMVSKEDVDCGCVQPKYSREGPNMYIQFLHSSEEDIDESKRKLSAEEALEILKKIRKEEMSILGFNSDRCVPASLILTCIPIPPPCARPYVQYGNQRSEDDLTLKLLDIVKTNIQLKRQTDRGAKSHVLQDLCSLLQFHITTLFDNDIPGMPIATTRSKKPIKAIRTRLKGKEGRLRGNLMGKRVDFSARTVITGDPNLNIDYIGVPKSVAMTLTFCETVTPLNYDNLKKLVERGPYEWPGAKYIIRDNGTKYDLRHVRRNSEKELEYGYKVERHMTDEDYILFNRQPSLHKMSIMGHKAKILPYSTFRLNLSVTSPYNADFDGDEMNLHLAQSHETRSEIKHLMIVQRQIVSPQGNKPVMGIVQDSLLAIRKFTRRDNFLTKEEVMSLLIWIPYWNHVIPTPAIIKPRALWTGKQIFSMLLQFDDMNIEDDKNDTANNKVGRDVNTNVNKDSSKMNTSGNYYYGNSTNDNNDDYLEKGNAYSRSGNNHPNSPLSIGDNINVGNVQQNDMSSPNNNNNNNNSNNNNNNIGGGINSFKRFNMVKINLMRDSSTSSKDDNPYCSINDGKVIIKNNELLSGIICKRTVGSSSGSLIHVLWHEMGPDKTKDFLSALQKVTNNWLEYVGFTVSCSDIIASNKVLGKVREILDKSKSEVSKLVEKAQKGELECQPGKSLYESFETRVNNELNCAREMAGKVASESLDERNNIFSMVASGSKGSIINISQIISCVGQQNVEGKRIPFGFNHRSLPHFIKFDYGPESRGFVSNSYLSGLTPQEVFFHAMGGREGIIDTACKTSETGYIQRRLIKAMEDVMVQYDRTVRNSYGDIIQFLYGEDGMAGEYIEDQIIDLMKLDNKEINKLYKYNFDEEPFGKDYYIGNKNDGSRNTSYIDYNKQNILNQEFEELYKCKNYLCKEIFPDGDIRQHLPINMNRLIEYAKSQFPCIPFVSNNNSTNNNNNNNNNNISNSRKLMDKGNLSSTHNHKESKKRRKRRRRKNKFDKFKNENNELMSEIKKEYENNDLNNMMISKGDQSPFKGMNEFHMGVADNDMGSDLGNNNNYNNDDFVDDDYVDDDYDDDDDDYDDDDDYDDDDLDDDENYSDNINIGGNRKYYGNTLKNNYDENSMLNPIDVVHKVNNFLEKLVIIKQINSNDTLSVEAQNNATILLKAHLRTYLNSKLLTQTHKVSVKGLDWLLQEIEKIFYKSLCHPGECVGALAAQSIGEPATQMTLNTFHFAGVGSKNVTLGVPRLKELINIVKNVKTPSTTIYLDDMVSNDQQKAKDILTKLEYTTLKQLTSHAQIIYDPNTTTTILEEDKSWVNEFYEFPDEDDTQYSLGEWVLRIQLTNIHVNEKKLTMKEIVYIIYSVFSSDELDIIYTDDNSEDLVLRIRVKYLNGEYNFMNYDVVDNANEQVDEQEEDEEHLVANDRGNYDETKNSTHPHHDYNNNTTNIFKSKVKNNISSDINTKNEDSISINSSNNEQVKNINSSPVSNNMHNNNNNNNNDSSNINDIKVKNIKKEDGNEGALRGGGDSNTSALFGNKNSQKEDNIVNNNNDNNDDDEEEEEEEEDFLFGDHNVSPKNTKDGKNKNTNNKSNNNENKNKKSGNNNSNNSNTYDDGDVDNDNDDDNDDNKSDITIKEDNDVAFMKTSTKNAEEDLELKNKNHIEHNISREDTEDTFLKKLMEQCLSTLKLRGIENITKVYMREESKITYDSDNGKFVRSSHWVLDTDGCNLENIFCAPQVDFKKTVSNDIVEIFEVLGIEAVRRALLKELRTVISFDSSYVNYRHLSILCDVMTQKGYLMSITRHGINRVDKGPLIKCSFEETVEILLEAAAFAQVDNLRGITENIMLGQLCKIGTGSFDIIIDNQKLNDANQNLETIQDLTSAGFTTPDSLHVITPDGLQSPVAINTINSPLPFSPTYNANLLSPTAPIDNVNNLLSPQYNLQNYGDNVMSPTSKDINNLDTLKLGGKFSPTQSPKSPTSVMHSPFSPFDHQNQQPVDATNLLFSPKNNNIMNYNVFSPKPNINNNVIQSPNIYSPNPMLDIFSPKPQINHNIYSPSYSPTSPTYNANNAYYSPTSPKNQNDQMNVNSQYNVMSPVYSVTSPKYSPTSPKYSPTSPKYSPTSPKYSPTSPKYSPTSPKYSPTSPKYSPTSPKYSPTSPKYSPTSPVAQNIASPNYSPYSITSPKFSPTSPAYSISSPVYDKSGVVNAHQPMSPAYILQSPVQIKQNVQDANMFSPIQQAHVDEAKNDDPFSPMPYNIDEDEMKENM
The following text describes a protein:
Function:
May be responsible for the uptake of short-chain fatty acids.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPISMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVTFFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPLLAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPKLLMEEADFQKQLPKDAPPSERLEESRILTLIIGALGIAYLAMYFSEHGFNITINTVNLMFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFINVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVIPAAQALGADLGKSVMAIAYGEQWMNMAQPFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF
The following text describes a protein:
Function:
Catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), which probably acts intracellularly as a second messenger perhaps by promoting cell proliferation.
Sequence:
MENNNNEPAETVQEKGPKLKNDIDLNDQFKDEKEKKEEISSSSIENKNNNNNNTSTNNVIPNESNNNISNNNVISNENNNTNNNTDNNTDNNNNNNNNNNNNNEPVTSFTVNNKSLIEKEPTLFEFNQEQQIKYKNKSINSLIIKRSGIVIKISQKKSTIIYQDSIIACSELPDNFDTATTTTTTTTTLPIKVTLFTCVLKKKQLTIDKEQRKRKSYTFQFKSNQDSLNFYSNIQSTFLNSLPRGNPKNRKIRILINPKSGKKESHNIFKEVEQLFKDSGIKMKLTVTMEPEHAKKIGFKSNIYKYDTVVFISGDGLLHEFINGLLSREDYEDAKKIPLALIPAGTGNGLANSIGLQDPMSAALAILRGFTKPLDVCIVQQPTVTTIPVVDNNTVTTTTTTTSPTSASPTITSANNNNNNNNNNNNNNNNNNNNNNNNNNSNITKWCSILSLTWGLVSDVDIESEKYRSLGDLRLIIGAAVRILNLRIYRGKVYFLPAIPLDKSQMQSIPKCSFDCNICDSSNSVKVIEDLVCNDNDNNNKNKNEEQNEINSTTSNNNNNNNTTTTSTSSSTSTSTSTSSLTATTTTAKSTNSLSSSPRSDINMSSNSISKSLDIGTIPSCKVTHNSNLLNESSDSLLSKGWKCIEGEFIGVVASTVSHLASDFISSPNAHLSDGLIDLIFINNRSKLSKASLLSILTDSATGDHLKSDLIEHHKVKALILEPSIQKHGIVAIDGERIPYAKTSMENIRGCLNLICRSYH
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
Sequence:
MSVLGELDLLGPRAHGAACGEAVLKAVAEDFQVDEVLEIPLSGEGEHLWLWVEKRGLNTEEAARRLGRAAGVQQKNVSYAGLKDRQALTRQWFSLHLPGKADPDLGAAEGADLRILRCTRHSRKLQRGAHAANGFTLRLTGLRAERAPLDARLERIAADGVPNYFGLQRFGHGGGNLVDARSCAEQDLLPANRNLRSRFLSAGRSYLFNRLLAERVAEGSWNRAAVGDLLAFTDSRSFFLAGEEECRDARLAALDLHPTGPLWGEGDPPSGAGVLDRELALAGREPALCRWLAKAGMAHERRILRLPIQGLAWHYPEPDVLQLEFVLPAGCFATVVVREILDLVPTGQTENPCAY
The following text describes a protein:
Function:
Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation. In glia, associates and targets CLCN2 at astrocytic processes and myelinated fiber tracts where it may regulate transcellular chloride flux involved in neuron excitability.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein; Cytoplasmic side. Cytoplasm.
Sequence:
MKREREALSRASRALRLSPFVYLLLIQPVPLEGVNITSPVRLIHGTVGKSALLSVQYSSTSSDKPVVKWQLKRDKPVTVVQSIGTEVIGTLRPDYRDRIRLFENGSLLLSDLQLADEGTYEVEISITDDTFTGEKTINLTVDVPISRPQVLVASTTVLELSEAFTLNCSHENGTKPSYTWLKDGKPLLNDSRMLLSPDQKVLTITRVLMEDDDLYSCVVENPISQVRSLPVKITVYKRLSRAVVLNLPNSIALFLVGAGLICRKKRKLEKQNSLEYMDQNDDRLKSEADTLPRSGEQERKNPMALYILKDKDSSEPDENPATEPRSTTEPGPPGYSVSPPVPGRSPGLPIRSARRYPRSPARSPATGRTHTSPPRAPSSPGRSRSSSRSLRTAGVHRIREQDEAGQVEISA
The following text describes a protein:
Function:
Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate.
Miscellaneous:
MISCELLANEOUS: Present with 768 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MSLMDNWKTDMESYDEGGLVANPNFEVLATFRYDPGFARQSASKKEIFETPDPRLGLRDEDIRQQIINEDYSSYLRVREVNSGGDLLENIQHPDAWKHDCKTIVCQRVEDMLQVIYERFFLLDEQYQRIRIALSYFKIDFSTSLNDLLKLLVENLINCKEGNSEYHEKIQKMINERQCYKMRVLVSKTGDIRIEAIPMPMEPILKLTTDYDSVSTYFIKTMLNGFLIDSTINWDVVVSSEPLNASAFTSFKTTSRDHYARARVRMQTAINNLRGSEPTSSVSQCEILFSNKSGLLMEGSITNVAVIQKDPNGSKKYVTPRLATGCLCGTMRHYLLRLGLIEEGDIDIGSLTVGNEVLLFNGVMGCIKGTVKTKY
The following text describes a protein:
Function:
Involved in middle stages of meiosis. Redundant with SPS22 for the organization of the beta-glucan layer of the spore wall.
Miscellaneous:
MISCELLANEOUS: Present with 238 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MPIWKTQTFFTSISVIQIVNKETKVSTKKEKDSMLNQLNTILRFLFLFLQLIKSSAAVEPNGGPNILDHNIMLVNTNATIPKKEQTDFEVISPTKQTQVDEDCKKGLYHIENAGNLIELQAKCWKVVGNIEISSNYSGSLIDLGLIREIEGDLIIKNNKHIFRIQGYNLESLGKLELDSLTSFVSLDFPALKEVETVDWRVLPILSSVVINGNIKKIKNIIISDTALTSIDYFNNVKKVDIFNINNNRFLENLFASLESVTKQLTVHSNAKELELDLSNLHTVENMTIKDVSEIKLAKLSSVNSSLEFIENQFSSLELPLLAKVQGTLGLIDNKNLKKLNFSNATDIQGGLMIANNTELAKIDFFPKLRQIGGAIYFEGSFDKIDLPELKLVKGSAYIKSSSEELNCEEFTSPKAGRSIIRGGKIECTSGMKSKMLNVDEEGNVLGKQETDNDNGKKEKGKNGAKSQGSSKKMENSAPKNIFIDAFKMSVYAVFTVLFSIIF
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. mL67/MHR1 also has extraribosomal functions, being involved in regulation of mitochondrial DNA recombination, maintenance and repair, and generation of homoplasmic cells. mL67/MHR1 also acts as transcription factor involved in regulation of RNA polymerase II-dependent transcription.
Miscellaneous:
MISCELLANEOUS: Present with 2610 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Sequence:
MKVNHSISRFRPASWFEKTKIIPPQVYIFRNLEYGQVLYSQFPNFSQTQVDKLFVRPNWSNRKPSLRRDIWKCMCVVNLQNYKQSVHLYQNLCRLRYLRDVAQRKESDKLRKKDSNGHVWYSGQYRPTYCQEAVADLRESLLKVFENATPAEKQTVPAKKPSIYWEDPWRMGDKDKHWNYDVFNALGLEHKLIQRVGNIAREESVILKELAKLESHPTEQTEVSSQ
The following text describes a protein:
Function:
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes The CSN complex is involved in the regulation of the mating pheromone response. PCI8 may also be involved in transcriptional and translational control (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDQFEVLVAVERLFFAWEQISDKETLVERLEGRLADMNLSLSTSPHRSLFLPYLGTRKDHNVADPDTISSEYGLQLLVLENALAHNYSKAISLLESSTVGDVGYIEWCRCMMRLNILGKSYGNNSELDIGLRSYLRNGAQGSSLLLTDEVSDCRMLGFASLFLQEEYFIAVHHMVRSIHEHPSLVDYLLREEDGRDIFILKEEYKLMLTIAVLVAIPLENYQDFLLLEDLNPLLQGLPELHVCLNLLVSTSFGSFFARWLGPIQELANRSCFLAPVWHSVNSHMRSKILVFYIKISERVTVSYLARTLDIPYDTVMADVSSLIQKFDINIGIEGDLVYYKEDLPVGNLVSKVSQIQREIDSKLLVMKQKNDALRSFIENMLKEQSVEPLNRSQDMDAFELHEQSEDEEYEEEHLEEGENV
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Sequence:
MIVKFHKTTERIKGLSFHPKQPWLLVGLHSGAIQMIDYRLGRTIEEFVQHEGPVRSVQFHQSLCLFISGSDDFTVRVWNYKTKKCQFVLRGHLDFIRCVHFHPELPWCVSASDDQTSRVWNYQSRQMLAIVTGHSHYVMHCEFHPTKDFLITCSLDQTIRLWSIAQLKKRFTQKNLQNDQQNELELIQILEGHNQGVNWCTFSPTENLILSASDDKKVKVWKFSDSRGFEIDSYQGHINNVSSAMFHPFGDYFISNSEDNTIRLWDMKKKVEIDCFTNYELDRFWVSAVHQNNNYFAGGSDSALYIFTLFRNRPAFDLIDNKILFVGSKKQIKIIDLQNNKEIVIKNFQEVATLISDNLLQDNIEFIQQNIYETSKNMLLIRLKQSSHNKQRGICKYMIFECQTNLSQIFLGKTAIFIGKYKILKSKENSEIEIYNFEVDSHKALGHKADKLFPYQGGKAIFYSDEMINVLDPEANQLVYQIPCSNEFNNMKKVLTNDTYVMIQTKKAIHLFTKSFQRVTQIQESINIKSVLFLSKTQNIIIYSTKVHIKYLLINGDSGIFGTMETVPYLIQLHEKYKLIYMNNVGTLLNMALDCSEMLFKQALIDKNIKYIQNFLQSHKKLGVLITSYLYQKGFPMIAYQLVEDKRAKFQLALSSNNLELSYRTCDDLKNPVCYQKLSEEAMRQGNHNIVEVCQQKLRSSQQLSFLYTITGQIDKLNVLSNIAKEQNEYNTRFQTLLHLGNYSQRVQFLQDCKLNHIANLSKLVHGLEYDQKLIIPEDLEWVQSLQPELLQPPVQIIKSKQHPLFSMNWPHNSVDQDDQYNILIVEDQENKERNQKSQEKPSQNQEKKNVNNCQIKKEDQTKENQDNEEAFEDCQWEINESELLEMQLNQATLDYKSLQYGYPDYKKVLSPVEQIITEQFQQCQQSLKSTKNVTNINLCKDQMKQLCLSSIIEISQIPFLQPAPQMISAVSDKQHFSRISQDLLKQGYKQTTDGKFQDALTTFKTLLRKALFYDKNTDIIPICLNYIIAMNCEIKKKDQSVSRQIELACYMAMCDLQPIHRSLTLRAAMSLAYKHKNHLTGAYVAKYLLKLLEKAPQGSAYAKVEVIENVKKILRNCEQSLRNEYEIDFEEDYLNQGTKILFADSLTIIKHQNFYQCLFDKAIYSQKGKLCQICDLCQMN
The following text describes a protein:
Function:
Involved in the bidirectional transport of formate during mixed-acid fermentation. Functions to maintain relatively constant intracellular formate levels during growth, using different mechanisms for efflux and uptake of the anion.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MASENQKLSSVALTPVEATDYAENTATYKANKRPFLSFMSGISAGACIALAFVFYTTTQTASAGAPWGLTKLVGGLVFSLGVIMVVILGSELFTSSTLTLVARVGGRITTTQMIRNWIVVYLGNFVGGLFIAAVIWFSGQTMAANGQWGLTILATAQHKIHHTWFEAFNLGILCNIMVCVAVWMSYSGKTVTDKAFIMIMPIGLFVASGFEHCVANMFMIPMGIITAHFSTPEFWQQIGVDPMKYADLDLYHFIVKNLIPVTLGNIVGGAICIGVFQRYLTKTH
The following text describes a protein:
Function:
Required for transport in the endocytic pathway and for correct sorting of the vacuolar hydrolases suggesting a possible intersection of the endocytic with the vacuolar sorting pathway. May be involved in recruiting the MON1-CCZ1 complex to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns[3]P) or other charged lipids, leading to recruitment of YPT7.
Miscellaneous:
MISCELLANEOUS: Present with 9380 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum. Note=Also found in association with endoplasmic reticulum vesicles having SED5 on their surface.
Sequence:
MLQFKLVLLGDSSVGKSSIVHRFVKDTFDELRESTIGAAFLSQSITIHPNDGNETKDVVIKFEIWDTAGQERYKSLAPMYYRNANAALVVYDITQEDSLQKARNWVDELKNKVGDDDLVIYLLGNKVDLCQETPSTETSPDSNEGGDEEQKVRAISTEEAKQYAQEQGLLFREVSAKTGEGVKEIFQDIGEKLYDLKKDEILSKQNRQIGGGNNGQVDINLQRPSTNDPTSCCS
The following text describes a protein:
Function:
Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.
Sequence:
MARGGRGGGSRNPANQSREVQVSKKISWLLRHGAGSEGLKLGKGGYVNVQDALNTRALKGLNITFPELRDAVVNNEKKRFSMILAASQDQSKSEEDAAQLEDLANETLETITESDNPADYLIRANQGHSIKVDVEGLLTPVTVEAGNVPDTVVHGTDEPAWRLILKSGGLRRMGRNHIHFASGLPAGFKSLAIDTASTEEKEAAPVISGMRKNSSILVYIDIQAALAANIKFYISENGVILTEGNEEGFLSYEFFKRVESRKKDGGVLMSDGKLPEGVVVDVEEWKKEVGDGRGKRGGRGGRGGRGGGRGGGKARANDDSRDLLADETA
The following text describes a protein:
Function:
Essential for sperm motility and is involved in the regulation of the beating frequency of motile cilia on the epithelial cells of the respiratory tract. Required for the establishment of radial spokes in sperm flagella.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme.
Sequence:
MPRHKTLVSIGHRIMKRFKQLDLRVDKEFVIYMVHLLARDRRKGLLKYDLNKPTACAIEGFVNTIVDSYVNSKDCTMANMKMAWVMKKGVTIDLEYVKKKYEEKFQTELQLLIKDILQYPETCSKVQLDQLFAKMQVFIVACYSLGSPKNHVLLKLTAQALNSVIGRSDLQNYVLKKKYHRLEYLQRLSATVGGIVIYNNDGPDGDRENVRSVVDDLEMAQKNTEAAFAASMGRAVKMQSTCQAALDDLINIDHKDETLTYRVPLEHLDRLNQFAATYFMLHRCLTTLNEHYQKTVYLIEVEHKRYQCVICKIDDTLSMRTAIDSELIFPHFVYLSQVWGNLNNYLNHIVELNKLREQVEALVVDDLMTLTKATIAELQALHKRIKKPKVCSFEERMDAVKELQTDGNFCKLNKADIKEFCSLAMTITNGLLMPAQVTRKLCSNVDITFGFRDPRYARFAELRFEPFIAAFRKVVFNNANLALLFKLDDALIEQELQNLVVEPPKQTDFECQTEMVVTNDLTPANWINVTWNAWDYHRETIHLANIRKKQTNDAQTNISYGRRNAQNQTYNCRQHK
The following text describes a protein:
Function:
Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MRRDDVSEGVSEKEEGDWNGLNDLLRKNGLPAVRFRRVGSGEVLPDRDSLFSAIHDFGVQLERKNETIEDLVLASKRNSRLQSRRDGELQTNEKKNEDTQRALEKAKAEIQRLKALQKTESESAELLSKKLKSSCIRLQQQLKVSEHRVKAKEVIVERMQTKLQQQVDKENMNKTRDRRAFRNLQDRDPRRANPRDIQALETIGVYEAQREQMQEETDHLKSQVAALNSELRDKDNLIARQSSAALRSEPPVWDECLDEGGAERASGSQSHFRYRPASSSVASDEMMLEQLEAARREQEVAAAKLRHREAVMIKKVAMIEQELLAARETIGELKEENANLTLEAESRPSIRDYRLSQRRIHQLERQVAENKLALEEASDLNELRKYMGTKELVERDRLNHRLHLNRLNTLPRETTLEVVKHVCRVLHLTDITLIAPSLDKLCSVVAAVPRMEKFIRDVCGFVFLHVNDNAETKDAGSARFELEQVLPTLQQWMMERRKLHALEGFKASIITELCKRTVGPGILNDTEDGNETESPPSHPTTLSRAVHIVSELVELEKSVIHHREIYTQAAAEVEVKSIEGVLPKINETYLFVNEMRNFLHAVRDLLYLEKDTSLVHCLNAIRERLQDNASNPAHAQQSDKHDGAGTNQENVYGGNTPNFVVERRRSQPSGNVAANAEANLVGVRQVREMSVLVRELKRELGAATMEEILPRTKRLMELLSLSIHNADPEDDEEYE