lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC. In association with TMEM209, may be involved in nuclear transport of various nuclear proteins in addition to MYC.
Subcellular Localization:
Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Note=Localized near the center, on both the cytoplasmic and nuclear side, of the NPC core structure.
Sequence:
MATPLAVNSAASLWGPYKDIWHKVGNALWRRQPEAVHLLDKILKKHKPDFISLFKNPPKNVQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQGLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSPLGKEDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPLLTEKQYIATIHSRLQDSQLWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMAELAIADNVFLFLMESVVVSEYFYQEEFYIRRVHNLITDFLALMPMKVKQLRNRADEDARMIHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPTEPLQTPTIMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSSHVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAFLQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRIPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVVNIARYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQKLMAGFVECLDCEDAEEFVRLEEGSELEKKLVAIRHETRIHILNLLITSLECNPPNLALYLLGFELKKPVSTTNLQDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPTMRYLRTSQDFLFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDMPVKPYSDGEGGIEDENRSVSGFLHFDTATKVRRKILNILDSIDFSQEIPEPLQLDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEISTVLQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHDKILDDEAAQELMPVVAGAVFTLTAHLSQAVLTEQKETSVLGPAEAHYAFMLDSCFTSPPPEENPLVGFASIGDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFLTRVAKIQQGALELLRSGVIVRLAQCQVYDMRPETDPQSMFGMRDPPMFIPTPVDRYRQILLPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGIISKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEGDKVSKKDEIELAMQQICANVMEYCQSLMLQSSPTFQHAVCLFTPSLSETVNRDGPRQDTQAPVVPYWRLPGLGIIIYLLKQSANDFFSYYDSHRQSVSKLQNVEQLPPDEIKELCQSVMPAGVDKISTAQKYVLARRRLVKVINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCMPTDSQDSLFASRTLFKSRRLQDSFASETNLDFRSGLAIVSQHDLDQLQADAINAFGESLQKKLLDIEGLYSKVRSRYSFIQALVRRIRGLLRISRN
The following text describes a protein:
Function:
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
Sequence:
MTMVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS
The following text describes a protein:
Function:
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Sequence:
MNKFVKSLLVAGSVAALAACSSSNNDAAGNGAAQTFGGYSVADLQQRYNTVYFGFDKYDITGEYVQILDAHAAYLNATPAAKVLVEGNTDERGTPEYNIALGQRRADAVKGYLAGKGVDAGKLGTVSYGEEKPAVLGHDEAAYSKNRRAVLAY
The following text describes a protein:
Function:
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Subcellular Localization:
Cytoplasm.
Sequence:
MSKVKTRFAPSPTGYLHLGNARTAIFSYLFARHNNGGFVLRIEDTDPERSKKEYEEMLIEDLKWLGIDWDEFYRQSERFDIYREYVNKLLESGHAYPCFCTPEELEKEREEARKKGIPYRYSGKCRHLTPEEVEKFKKEGKPFAIRFKVPENRTVVFEDLIKGHIAINTDDFGDFVIVRSDGSPTYNFVVVVDDALMGITHVIRGEDHIPNTPKQILIYEALGFPVPKFAHLPVILGEDRSKLSKRHGAVSVRAYREEGYMPEALFNYLCLLGWSPPEEGREIFSKEELIKIFDLKDVNDSPAVFNKEKLKWMNGVYIREVLPLDVLLERAIPFLEKAGYDTSDREYIKKVLEYTRDSFDTLSEMVDRLRPFFVDEFEIPEELWSFLDDEKAYQVLSAFLEKIREKKPETPQEVKKLAKEIQKALKVKPPQVWKPLRIALTGELEGVGIDILIAVLPKEKIEKRILRVLEKLS
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MALNVYRLSILIFVIHIPLVSSSGDWSYTGENGPNHWGSLCRSGSQQSPINIDIGKSKHDQELGQFIFSPDYFNYTFKYNLSNNGHSVMLTPDSSAQLTVSGGGLPGTYRLAQFHFHWGGPSSAGSEHTLNNKQYQAEVHLVHYNLNYDNIGSAATSKDGLAVIGVFLEAGKSVGNVVIEKIANRLSNSCATVLSSNCTIDNMRLIDILPFNHDNYFRYQGSLTTPPCSESVVWTVFQKPISVTKEQLQSFFRIQDSHSHELHNNFRPVQKYKKPVTKSFSSEGSRHVLTISVLAFSSLVALYSAKLF
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGICMDESVSLSHSGSAPDVPAVSVIVKNTSRQESFEAEKDHITPSLLHNGFRGSDLPPDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIKPKHSDSYFPPPLGCGAVGGPVLEALAKFPVPELHMFDHFCKKEPKPEPLPLGSQQEHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPPRQRLKPAHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPLEATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGARKGDESMTKASDSSSPSCSSGPRVPKGAAPGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQRRSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSPKHGLTSGSASPPPPALPLYPDPVRLIRYSIKCLECHKQMRDYMVLAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLLFVQKPELMQHVKSTHGVPRNVDELSSLQSSADTSSSRPGSRVPTEPPATSVAARSSSLPSGRWGRPEAHRRVEARPRLRNTGWTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLSQTSKVKPPGGHSPQVNHLKRPVSGVGDAPGTSNGATVSSTKRHKSLFQCAKCSFATDSGLEFQSHIPQHQVDSSTAQCLLCGLCYTSASSLSRHLFIVHKVRDQEEEEEEEAAAAEMAVEVAEPEEGSGEEVPMETRENGLEECAGEPLSADPEARRLLGPAPEDDGGHNDHSQPQASQDQDSHTLSPQV
The following text describes a protein:
Function:
TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May function as a coactivator by serving as a site of protein-protein contact between activators like Sp1 (or btd) and TFIID complex.
Subcellular Localization:
Nucleus.
Sequence:
MNTSQTAAGNRITFTSQPLPNGTISIAGNPGAVISTAQLPNTTTIKTIQAGIGGQHQGLQQVHHVQQQQQSQQQQQQQQQTQSAGQPLLNSMLPAGVVVGMRQQAPSQQQQKNVPTNPLSRVVINSHMAGVRPQSPSITLSTLNTGQTPALLVKTDNGFQLLRVGTTTGPPTVTQTITNTSNNSNTTSTTNHPTTTQIRLQTVPAAASMTNTTATSNIIVNSVASSGYANSSQPPHLTQLNAQAPQLPQITQIQTIPAQQSQQQQVNNVSSAGGTATAVSSTTAATTTQQGNTKEKCRKFLANLIELSTREPKPVEKNVRTLIQELVNANVEPEEFCDRLERLLNASPQPCLIGFLKKSLPLLRQALYTKELVIEGIKPPPQHVLGLAGLSQQLPKIQAQIRPIGPSQTTTIGQTQVRMITPNALGTPRPTIGHTTISKQPPNIRLPTAPRLVNTGGIRTQIPSLQVPGQANIVQIRGPQHAQLQRTGSVQIRATTRPPNSVPTANKLTAVKVGQTQIKAITPSLHPPSLAAISGGPPPTPTLSVLSTLNSASTTTLPIPSLPTVHLPPEALRAREQMQNSLNHNSNHFDAKLVEIKAPSLHPPHMERINASLTPIGAKTMARPPPAINKAIGKKKRDAMEMDAKLNTSSGGAASAANSFFQQSSMSSMYGDDDINDVAAMGGVNLAEESQRILGCTENIGTQIRSCKDEVFLNLPSLQARIRAITSEAGLDEPSQDVAVLISHACQERLKNIVEKLAVIAEHRIDVIKLDPRYEPAKDVRGQIKFLEELDKAEQKRHEELEREMLLRAAKSRSRVEDPEQAKMKARAKEMQRAEMEELRQRDANLTALQAIGPRKKLKLDGETVSSGAGSSGGGVLSSSGSAPTTLRPRIKRVNLRDMLFYMEQEREFCRSSMLFKTYLK
The following text describes a protein:
Function:
Antiporter specific for GDP-l-fucose and depending on the concomitant reverse transport of GMP. Involved in GDP-fucose import from the cytoplasm into the Golgi lumen.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MNIQNDKERLLNGSIDEIEIITTDNNENDTIRNDDILKNSQLREQQQHQQIQQQIQQQKKESSLSTIASVIAFYFFISISLVFLNKILLSDFKFEYPLFITWYQQIISFVSIYIMTSISKSVPALSFLPEFEFKSATASKVLPVTAVLTGMVIFNNLCLEYVEVSFYQVARSLTICFSLILTYIVLKSKTSYRATMACLVVFLGFVLGSAGEVNFSWLGIIFGLLSSFFVALYSIAVKRVLPAVDGNEWRLSIYNTAISIGLIFPLILVSGEANTILDEPLLYSGTFWFYMTVAGLMGYLISISVFMQIKHTSPLTNTISGTVKACVQTILAVVFWGNPISTQNAVGILLVIGGSFWYSMQRFFEMKK
The following text describes a protein:
Function:
Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2) by facilitating the incorporation of copper into the Cu(A) site of MT-CO2/COX2. Could also act as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MLRLRVFDRHKRLWSVLQSTIRGNNISNHIPNTTCRSSAPPHLCARQRAFYSQNSPKTPNPGSSAGIKLRTRLVVTLLFGGGIIGTWWYVHQEKEKRIQMQRLEQLRKVALGQGDFHLLDHTGQRRTKRDFLGHWVLLYFGFTHCPDICPDELEKLTSVVHILDKDPSLPSVQPLFITVDPERDDVSAMARYVKDFHPRLVGLTGSAEEVKQAGRDFRVYASNGPKDEDGDYIVDHSIVIYLVNPDGLFIDYYNRMKNDTQIAESIRNHMKTFVRLFPD
The following text describes a protein:
Function:
Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MMRKKGKVKADAGSKRGILQTVITTKTKPPKRVKAKEAAQPSASEDEEFADAEPTVDFSHRSDADGADNELNSEASEASGDDDFELEDKPEGEIRNDLASMSFEELHALKEKIGLKMYKEAVFGVDRKKSKKNFKRDNKNRPREQSAKHQVPVYREVFQVKKKVHQDPRFSSRAGDFDERVFRETYSFVQDIKAKEREELAEMIRNEKDPSRRKTLRGLLQKMQNQEASERIKSKKVELEKQYHKFLVGHKGDNKPLYLNKTEKRKIELAERFKELKKAGKLEKYLEKKRKKNVRKERKLLPALG
The following text describes a protein:
Function:
Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. Controls the subcellular localization of the homeodomain protein BLH1. Plays a role in the regulation of cell elongation by controlling the expression of GA20OX1, a gene that encodes a key enzyme in gibberellin biosynthesis. May play a role in double-stranded DNA repair through the DNA non-homologous end joining (NHEJ) pathway along with KU70 and KU80 protein complex. Possesses DNA-binding activity towards double-stranded and single-stranded DNA in vitro.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing OFP1 show stunted growth with general delayed development and shortening and thickening of all aerial parts. Leaves are irregularly heart-shaped and lobed and display curved surfaces. Anthers are short with a thick filament and style and stigma protruded from the flower. Siliques are short and uneven and produce few seeds.
Subcellular Localization:
Nucleus.
Sequence:
MGNNYRFKLSELIPNAWFYKLRDMSKSKKKNLQSQPNSTTSKKKHHAVPTPTSTTPLSPRPPRRPSHSSKAPPSHPPRKSSGNRLRHRATVDSKSSTTSGDSTTTETGSFSPDFRSDQVLLPDESLTGSWHSPCSSKLSKTATFTPPPELELRPIITKTAATARKTAVNSPAGVRLRMRSPRISVSSSARRSGSSARRSRAVVKASVDPKRDFKESMEEMIAENKIRATKDLEELLACYLCLNSDEYHAIIINVFKQIWLDLNLPPPHSK
The following text describes a protein:
Function:
Catalyzes the covalent attachment of ubiquitin to other proteins.
Sequence:
MSSRSKERVVTAFRKIFHKSSNNNNNNNNNHNNNINNNNNNDKVDGATGSSPNINNNNNNNNNNNNHDGAAAPSSAGGVAVAGGAVGSSGSSGAAKNAVVRMAAEQAVWDSPGKRRRQDHKVAPTTERQLVAAPDHTIRTRRLMKEYREMERLQAKNDAVFTVELVNDSLFEWHVRLHVIDPDSPLARDMAEMGVPAILLHLSFPDNFPFAPPFMRVVEPHIEKGYVMEGGAICMELLTPRGWASAYTVEAVIMQFAASVVKGQGRIARKPKSTKEFTRRQAEESFRSLVKTHEKYGWVTPALSDG
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MEANSMRKLLGSSTMRTISFAACLMALPLIIMLSVNYQDQMFNLIGKVKVLGGQALNVRQIGSEHEPASISDDVLLGGLLASEFDKDSCLSRSEAVLYRKPSSKKPSPYLISKLRNYENLHKRCGPDTESYKRTLLENLLPEVDKQRLVASPSKNQTSKSVLIASLYPQFYENMTNMYWTFPTRKGEVIGVYQPSHEEYQHFGDNMHNVKAWVEMNLLSLSNVLVTSSGSTFGYVAQGLGDLRPWILYRPENWKDSDAACHPGKSMEPCLHIPPSHDCKAKRNFDMGTVVPYVKHCEDSTSGLKLINPDNNSR
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSKAGDESSGGGYDAASAAAASGGGELAGRKMVEGKSKFSVTCGRLSQYLKNNGSFGDLKLGISHSFQPQAQSVTPTRQTKPPPPIIDLSSDHSDECPSSPTSFLPDLNTTTRTQISHNRHFVSTPKNPEMDQGSQMTIFYRGRILVFDHFTIDKVNELVAIANRRSAPIAAANSVNFQQSTSQSTPNSLPDRFNCPPPQNTSPVSTSGNSQIPIHNTPAVATPHMSIASDLPIARRVSLNRFLEKRKGRIVSKAPYQVNGSPDISSADILTPEKKGEEGCSGFGKPEKRPMTSVVPGEESSHGKMTIESQSPEEKKWLGLATQSSEPEIRRQ
The following text describes a protein:
Function:
Regulator of sister chromatid cohesion in mitosis. Probably involved in development of the central nervous system.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MVRTRPVPCVPSPDVNTATRRNPGRPKKQSIGADLSTTISKPGRPKKLSIGADLTTIRKPGRPKKLGADLTTIIRKPGRPTKLSNKQSLTALNEPECRIRKCVVKIRRIKVKNGVVSEISRNDAPDVDASTFEPARNSTMYIPSKVQKSTQPQNIKENVAGPETSPCQQRIRSKSPSGPAAEISPKKPPRFFHRDQPLTRTRSSVTRNVFDFLSQSQIEDDSDREDPAADIIQRLVKDGKACVMVRSRKIGKPRAKRTAKKVRPVGNRRKVSTKDNEPEPVKVVPKSIEPRLQKPSRSLSTIFEPEEDYSNDSEHGYVQPIEVPVQVHVEPSTSKQAHEGAYSNLARSVMLNQTQAQNPLPSTDRRRELINMARQLVSTPLNRRAPPVTDVSATTTALSPIAHQSPNAVRTAGGKSPWRVSDDSPLPNTFMFGFNNSQMPSYSSDHVQRRHVYVPDSPVEHAENIPHEESICPPLHEQNHDSNANDSNEENRPPPTISKSMSINDQESEENAENFVHLPNPRRTLQKRTPFKDINILEVVTLPSWKKNVTATVSKEITPTRVAPRPMATSSPAQRSQTRSNLFGFDDDFACEDIPRKSTTPSKGIAPTSMSLNREVTPALANRNQTEVNTFGCNEILPCENIPKEKETNTEERTSSSQNLFGFDEFITESQDSPANFTGLSQNVNLHDKLHRLAELRPRDGELPQVSYTSIRSDCLGESHSKQTDIRYMLCSTMIAPPRPAKRKPAAPTARESMGLFRVDQDEPEQSFADKQPRRTYVKERPQRKRKKRVQILYIESESEDEDEQDSHDKSLDSPEKKRHHVKRPRRDIEHEAKLEQFVTSFNKQCEEVEKFPVIIE
The following text describes a protein:
Function:
Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.
Subcellular Localization:
Nucleus.
Sequence:
MEESKDSDDEQILSKMANHFHKLVSDKEELRTAVECFFNNLVDELTLGIIFDEHRKFKTGVYQPEMEVANVEELPVGAEVFPEQDVSKITCKCPNCGRVVAAIRFAPHLATCMGVGRTRSTRSTRKRMASSSLERKNSSFSEEPSDDKDDEDGNWESKRPKKKKRNESKKSKSVETPKTFCDSSPSDDIDVEAVDECPLLRGLLLGYLNSSSMADSASSISLNLPKKKAKTGNKKGKKVKVLPNPTTIRLHHPLA
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MVDAVSRYDDDEEDDALPFEGLDKASALQECRVFNKIPLDEEGSIRAMTQVLYLLSIGVRLTEAEATDIFFMSTKLMQSNYAKLRRLQYILMKELSPLVEQSFIASNALMTDIKKKGDSDKSSAIRALYAIMDSSMYNSMDRTIVECMTSRNPSVVTAALVTGIHMSNTLPEMPRKWATQLNEVLRERSKAQYPAIALLHKIRNNDRLSVDRLIEDAQAGRVRSSLAVCIIIKMCTELMQDDFTSSLEIYKFVTSMLHRSDMIAFEAAKSIASLRNVSDRELTPVVTMLQLYLSSQNQVLRFAAVYLIGRISTTHPAAVAPINAEIEALALDPNRVIATLAITSLLKTGTESTIGRMLTQLSSGSYMSELGDQLKLTIVDAMRVLNAKFPSKYETLLAFLFRALSDEGSSSLKQSVVDAMLDISNSNPSSKEVVLTHLAEFIDDCEFSQITKRVLMHLGEGVPHCSNPRHFVRYVYNHATLEKPEVRAVAVATLAKIAASVPSLRRSIVALLKRSCSDGDDEVRDRAVLYTKLFLQNDDTLVRTYVENVAAAVQHQRHTLREAHKKTSADGVLGGSTSADTMVAIAAAPNHTDASGMPAPTPAILQGRDALHHVRQLRELGEPAKSTEPVLITEADNEYVVSVMKHVYPEHVVVQFKVKNMMDNMLFKNVIVVTNTEELEAEPLYAIPIESIRPGETQYGYVVLQYAPGKFPSGTVEPMFRFAMAEREDEDAGDHDEYPMESFDVDVCDFVTPIDLGNSMEDKWAEQEGNETAGTFALHSMKNLTEAAQQLADFFGMHIEGGVPEKITTTSHVVKMSGVLADEDRTLVLVQAKVFIATDNHVALHLALRGGSADIREYLANVLLR
The following text describes a protein:
Function:
Has abundant triacylglycerol lipase activity.
Sequence:
MLQRSTKAEESAVPRPKRPIMDFLEVEGGWSLSFSGSGYLGLYHVGATECLRQRAPRLIQGARRFYGSSSGALNALSIICGKSADFTCSNLLAMVKHVERLSLGIFHPAYGPIEHIKKKLQDDLPDNSHIVASQRLGISLTRWPDGQNFIVTDFATRDELIQALVCTLYFPFYCGTIPPAFRGERFIDGALSNNLPFSNCPTTITVSPFNGTVDICPQSTSSSLFELTAFNASFQISTRNFFLGFKSLFPPKPEVVADYCRQGYLDALRFLERRGLTKEPVLWSLVSKEPPALVEGPRGTDHNQGQEAGLIVRWDIPNVLVKDVPNFELLSPELEAALKKACKRDFWAQIQCSVPGKVLTYLLLPCTLPFEYAYFRSRRLMQWLPEVPDDLYWMQGLLKTTTLKVYSMAKSWLLSLGSPLVTSADAGLLWQQQGTAAAGNRPLNHRLADCALG
The following text describes a protein:
Function:
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
Subcellular Localization:
Cytoplasm.
Domain:
The MATH/TRAF domain binds to receptor cytoplasmic domains.
Sequence:
MTTTISQLNITPIKFTINDLIVDPVSLSENFNCPICEECIMDVNKCEALQCKEGHVHCRLCWMKSLESKKECMTCRTRVNSVDSLSKNIYLQKEFRNKKIFCPNLFRILNSGKIEIDEKFGCKEILKVDELEGHIKECQFQFIECPNDKECKTRLRKNQLKDHAEKCKKLKSECEFCGEKGLVIDDSKVHYSECEKFPIKCPQNCNSPTFNCTIERGRIKYHIENECPFTVIQCKYREAGCMLEFPRSELSEHMKLIDHSKYMEATIDQHICKFEKSEKEYKKLELEYNRLKDDFKILQSELKVIRELKFNYQNKWVITNWSQKLQDYPKPKSIESPEFMVGNLKFKIQFYPNGGLSDESKDFLSIYLYKFDDQTPSKVQFSFELLNKDFTRNRKLASTNIFHTENKWGWRSFINNSLVTTQTGFVIQNSVTLNINIEILPEEKEAFTS
The following text describes a protein:
Function:
Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine.
Subcellular Localization:
Mitochondrion outer membrane; Multi-pass membrane protein.
Sequence:
MSSWLQRQVGQQQAQLAVTAVVSGAAVAGAILGYQALRRKEAVQQLKASIPPIDERHHAEKLTEYGTAASSTHLNKEDERSAALARRAQEGDYDDDLILEQLARNRVFLTDEGLAKLRSSFIIVVGCGGVGSHAVASLARSGVAKIRLIDFDQVTLSSLNRHALATLADVGTPKVHCIRKRLGQIVPWVKFDCRNELFGGSAAADLLAPWSWDDSDKGRKPDYVLDCIDNITSKVELLHYCHSNSIPVISSMGAGCKSDPTRIMVGDISLSTDDPLSRSTRRRLKLLGVNSGIPVVFSTEKPGPGKASLLPLAEEEFAKGQVGELGVLPDFRVRILPVLGTMPAVFGYTVANHVICDISGYPNDYNVGGKGREKLYDSIIASLQGLHERLARAEAGQDLIGLRIPISKDDVGYLVEEIWRGRSAISNLTNRLILVPWQRPARGFLPDPEWEKEGQKFIPIDLKNLVCMTKEEGARHEREVLRGGKDVTEVYDPKVLEKVKWHMAEVEVQEKFR
The following text describes a protein:
Function:
Involved in a high affinity multicomponent binding-protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEVLQQLGTYYSQNGGYVLQEFYRHFLMSVYGVLFAAIVGIPLGILIARYRRLSGWVFAVTNVIQTIPALAMLAVLMLVMGLGANTVILSLFLYSLLPIIRNTYTGIISIEHAYLESGKAMGMTKFQVLRMVELPLALSVIMAGLRTALVIAIGITAIGTFVGAGGLGDIIVRGSNATNGTAIILAGAIPTALMAVIADLVMGWLERALSPIKKKKGNFIIADRKTTSI
The following text describes a protein:
Function:
Plays a role in alae formation in dauer larvae probably by regulating cuticle assembly.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MRPIPYDISLSITSFLSLILICSANPIDNGLVDSELIHECVTHKAVEVILLLDASGSIGDDTFKKQLSFAMHLASRLNISEDGSHMALIQYAETPKLEFSLGQFNHPTQLEWAIQRIEYQSGATNTGQALRLTLEKGLQGARPGIPKVAIVITDGQSQDDVSEPSQLLRDADVMVYAIGVTNLVNVHQLHQMTGNPVRVFTVESFEQLDRALADSLTWSMCKTEFRPGTPEIICGPDRIGVKASTKQPFEGNVFVMDHYHDEECRAGPEKFPDSRSIGLTVPFSACNVHRYRSLNPKGIFVEVSIVFMFHSLFMTKTDQTVKVQCFYMEADKHVTVPLSVSMITTVFREQIYQMPQCAYTLRKGAPDGPIVRFATLGESVYHRWECIEVEGADKDTFGMLVHSCYVDNGYGDRVDILDSNGCGLDAVLLSTPDYDTSLRLATKPYHVFKYADRPVLQFQCQITLCLKYDGGCEGITPPQNCKKLPGEDGHHHHHHPEKRRKLVRRLADGVGTIDVFTDSVTVLEQEPACQQPLPYPLINTNLWIMGIITLTNIFVFILTVWFTFRKRRCKPA
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MAESSSSIKNKAGASKCSSDEEEKVGNIDLGLSMKNLSLGPKKKLLIMGIGGFLCHRVCYRYGRQKIPTHRLPDASYGSFYVYKRPFCEDFMKFCLERFEVGIWSSAKEWYLDSALDSIMHGLRSRLLFAWDQGECTKTCFFDLENKSKPIFLKELKKVWEGNGVGILRSSTQFCSSNTLLIDNEPYKVLLNPPNTAIFPNEYKADDTNDDALGAGSELRRFLEKVADAKDVSNFIKHNPFGNPPISPHHPNWDFYSKIITSYK
The following text describes a protein:
Function:
Involved in cell cycle regulation. May be a regulatory subunit of CDKD-1/CAK-R2.
Sequence:
MADFRTSTHRERWIFQTNDLMDRWGAANQRATETLVQYGTTRLKVDPVDGSLSYPEPAPDHVVGSSGVKPLSCEEERLMRVFYEQKIQEVCSAFKFPHKIQATAIIYFKRFYLQWSVMEHHPKHIMLTCIYSSCKVEENHVSAEELGKGIQQDHQIILNNEMIVLKSLDFDLIVYAPYRSIEGFVDDMEDFCRAGNGEHQRLQDLRQTAISQVDKMMLTDAPLLYTPGQLALAALHKSNDMHKILNFERYLESVFSRQHSDCPIEQFVGSINMINYLVEQLKIPTPKDMRHIDRKLKHCLDPSSQDEHKKKEKKSKHKSKRAANEAQLDS
The following text describes a protein:
Function:
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol.
Sequence:
MVKVEVEYCGICNFSGQCHLLREFLLASSPDLDISCRTGRRGSFEVSIDGQLVHSKLSCLAFPQHASVLAQVQKAERGEPVEKVLEQPIKDCVVM
The following text describes a protein:
Function:
Sulfotransferase involved in dorsoventral axis patterning in early embryos. Required for the ventral activation of ea/easter by the protease snk in the perivitelline space between the embryonic membrane and the eggshell; activation of ea requires both activation of the ndl-gd-snk protease cascade and sulfation of a vitelline membrane component by pip. Probably acts by mediating the sulfation of some glycoprotein or glycosaminoglycan stably deposited in the vitelline membrane, whose ventrally localized modification leads to spatially restricted activation of the protease cascade resulting in localized activation of the spz Toll receptor ligand by ea (Probable); [Isoform A]: Probably required redundantly with isoform H for dorsoventral axis patterning in embryos. Lacks 2-O-sulfotransferase activity towards completely desulfated N-sulfated (CDSNS) heparin, chondroitin, and chondroitin sulfate A, B (dermatan sulfate), and C. Sulfates several components of the eggshell vitelline membrane, including Vml, Vm26Aa, Vm32E and psd/palisade/Fcp26Aa; [Isoform H]: Probably required redundantly with isoform A for dorsoventral axis patterning in embryos; [Isoform F]: Lacks 2-O-sulfotransferase activity towards CDSNS heparin, chondroitin, and chondroitin sulfate A, B (dermatan sulfate), and C.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein. Note=Wbl/windbeutel is required for targeting to the Golgi.
Sequence:
MSLNAERSYKMKLRDVENAFKYRRIPYPKRSVELIALLAISCTFFLFMHTNKLNSRLKEMEVKLQPSEFSALGLTGNHISGHDAGKHDDINTLHGTYQYLKSTGQKVGYNVHDRRSSEEQLRTPTAHGHHHDHHSHHHHMHQQEKIDGHKHKASHDKQLAVPDNKHKEDEVHYEDDEDEVEENDDDLANDVGTTDSEGFNFKADLLNNTKYAEVDFVFFNRVPKVGSQSLMELMARLGKINGFTHARNKGSAHETIVMNKQRQNDLIADLLTRPKPHIYSQHIAYINFTRFHLPKPIYINLIRDPIDRIISWHYYIRAPWYYRDMQAKLGENAIPMPSEEFMNLDLDTCVRNHDPHCTFTQMQIKNPVGDHRRQTLFFCGMNQKLCMPFNSEAAMQKAKRTVETEYAVVGTWEDTNITLSVLEAYIPRYFRNAKVAYYLGKDRLSRVNRNNVTRIVSDETRLILRKNLTNEIEFYEFCKQRLYLQYAALSHGKRFGEDDYLLVPEQQNEYNEDY
The following text describes a protein:
Function:
Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.
Sequence:
MATKRAWKLQELVAHSSNVNCLALGPMSGRVMVTGGEDKKVNLWAVGKQNCIISLSGHTSPVDSVKFNSSEELVVAGSQSGTMKIYDLEPAKIVRTLTGHRNSIRCMDFHPFGEFVASGSTDTNVKLWDVRRKGCIYTYKGHSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTMGKLFQEFKNHTGGVTGIEFHPNEFLLASGSSDRTVQFWDLETFQLVSSTSPGASAVRSISFHPDGSYLFCSSQDMLHAFGWEPIRCFDTFSVGWGKVADTVIASTQLIGASFNATNVSVYVADLSRMSTTGIAQEPQSQPSKTPSGGAEEVPSKPLTASGRKNFVRERPHTTSSKQRQPDVKSEPERQSPTQDEGVKDDDATDIKDPDSYAKIFSPKTRVDHSPERNAQPFPAPLDVPGAQEPEPFKHPPKPAAAAAVAPVSRAPAPSASDWQPAQANPAPNRVPAATKPVPAQEVAPSRKPDPISTIIPSDRNKPANLDMDAFLPPAHAQQAPRVNAPASRKQSDSERIEGLRKGHDSMCQVLSSRHRNLDVVRAIWTAGDAKTSVESVVNMKDQAILVDILNIMLLKKSLWNLDMCVVVLPRLKELLSSKYENYVHTSCACLKLILKNFTSLFNQNIKCPPSGIDITREERYNKCSKCYSYLIATRGYVEEKQHVSGKLGSSFRELHLLLDQLE