lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in ciliogenesis.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Sequence:
MANPHRTNVLLTSCLKAPVDPHTKAPLASYERGAVLTHATAGQLDNRDYEKELEFWDSGSDFCDEDCLGMGGAHVGGSFRAAVDRLDLSEIFFSNEEYYSKLEELKRAHERTMAELESMYQQKLQLRSGEAFDMKALDIGHRLQWTNMSPATSRHCLRKSHSAGELRRDSVLSDSSEEDDAPNDVEKGLLFSPKEHIKNMWRDFKVSSYNHQLSSSLQSLQGGQKKAQQRRQGKKSGRRDKHRVTVPKPFHMTLREAQRRKLGIKTRSEIELENMELRRQLEEVTECQRKFRASPVPAHVHLPLYEELRERSEERRRTLQEREEKHLGTVQKPFSFIERERLKKEQKQQGQPSDQEKVKPFKAKPVPKSVYAAASGEQLKEEQLYRSIKIQMRAQEMLQSSSMPPSMLTRRLSDRKKNKDGSAAEGAGSFSHRPQINKEVPDFDAKHRRFQKHLEKRKEVKPTTTCEPFELRTSQISSHKERILAELEKEQSSPRMRRWPCVSPGAVRTPNSSLCSSLSGSLELLPAKITDATKKRHEAVRYHFSTPEPSVIVVEMLKACPL
The following text describes a protein:
Function:
Functions as a component of both the DNA-binding general transcription initiation factor complex TFIID and the transcription coactivator SAGA complex. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription. SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription. At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B. SAGA interacts with DNA via upstream activating sequences (UASs).
Subcellular Localization:
Nucleus.
Sequence:
MSEPINKPEDEEMDVEFNDVDDQIVPDELPEQAQKQDDQQPQQSQSQTAETKIDTGDSAKPQNDATSSTAHPTGTANGTPPASVIPELPDLTRKDKSLKEVLDLMDGDFAPIIPDAVTDYYLAKNGFETSDIKIKRLLALATQKFISDIAQDAYEYSRIRSASAVYNSSNPQVRAKLLLQGQQYANQQTLTGNANNNGEGDQQQSSQSHSNAGNQQGKIVLTMEDLSNALSEYGMNTSRPDFYR
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
LLVILGTRPVSGDMFSASADLANTFRLEQKVVNVLGELVAQTEAKLSIIRHYLEDYQSVVEEKASSEEEFIERVAGNPIHAYRLMKRLYFDWQTVEKEIKADNWRSIFAFIITLILERVRMGAKFPKEEDFFGAAQALVRLQDTYELNMTQLARGNLWGRQTRAELTAQDCLFMGKHAFNARAYARAVEWFEESYILAGLENNKTIRQDQVMEFIQHAINMQTKQGKPMAVLSHTNSFELPLRERPAVVQRSEIIRSRKYNVGKHISDQDDASNFNALCRGERLLNDKLLAELKCWYDTRHQFYFLLMPIKIEQHSFEPAIYTFHDVLSDEEIETIKELAKPLLARSMVQGKLGVGHEVSNVRTSKTAWLPEGLHPLLNRLSRRIGLITGLKTDPIRDEAELLQVANYGIGGHYSPHHDYLMKDKADFEYMHHRELQAGDRIATFMFYLNDVERGGSTAFPRAGVAVKPVKGGAAFWFNLKRSGKPDPLTLHGACPVLLGHKWVSNKWIRETAQTFNRRCLLD
The following text describes a protein:
Function:
Plays a role in the adhesion to host cells. Involved in the adhesion to host apoptotic cells thereby facilitating their phagocytosis.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Extracellular side. Note=Appears to localize to some vesicle-like structures.
Sequence:
MFAFLLFIAFTSATNIILDLDQEVKDTNIYGVFLKNEASPEKLEEAEEKEKSSSAKPESSSNEDNEDDEDEKASSSDNSESSSSDKPDNKPEASSSDKPEASSSDKPDNKPEASSSDKPDNKPEASSSDKPDNKPEASSSDKPDNKPEASSSDKPDNKPEASSTNKPEASSTNKPEASSTNKPEASSTNKPEASSTSNSNDKSGSSSDNDNNNLDAASSPFIVFCAIIIAIIF
The following text describes a protein:
Function:
Not yet known.
Sequence:
MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQAIFQEMAKEIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQAIFDAVDELSQESHGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVKPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKITFRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYEQKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDKLIDANGGPVWTEEGFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLPPARREDEDVKEIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG
The following text describes a protein:
Function:
Confers resistance to low temperatures by limiting chloroplast damage and cell death, thus maintaining growth homeostasis. Regulates steryl-esters and sterols accumulation. Limits leaf necrosis associated with virulent bacterial infection (e.g. Pseudomonas syringae pv. tomato DC3000).
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The TIR domain mediates NAD(+) hydrolase (NADase) activity. Self-association of TIR domains is required for NADase activity.
Sequence:
MSTSYSFLLAGRELDVFLSFSGKIALDVDFGYDLSRNGIKAFKSESWKESSFKPIDLRTLEALTESKVAVVMTSDEEVSSVGFLEELIVIIEFQEKRSLTVIPVFLTKHPLDVEKVSQIFPERAKIWRTAIAKLDNIAAQYSFSRNLAVMHGTHRIKQIADDIRLMFLSSASSDFKGLAGMDRHMKALYALLALESDEKVRTIGIWGSSGVGKTTLARYTYAEISVKFQAHVFLENVENMKEMLLPSENFEGEDLRSVNHEMNEMAEAKQKHRKVLLIADGVNNIEQGKWIAENANWFAPGSRVILITQEKSLLVQSGVNHVYEVGSLRYDEALQLFSRFAFKQPYPSPDFERLSVRAVQLAGFLPVTIRLFGSFLTGRDKEEWEATLLKLNAKQGKDIKEVWKIMEALEDKDIVEASQR
The following text describes a protein:
Function:
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
Subcellular Localization:
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Domain:
Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
Sequence:
MSSRDFSNDLFSINIEENAGCVVSAKVQANPLVTQKCHKEALKTVKKNVVLPGFRKGKAPDNIVESRYSTQMEQELRRLFLRASFEALSQMCDRKPLSPKAVRSSAIDTCNPVNGGSVSFLYEAFPVIPSLPWEQLSLPDPEPVKEISEEDLENGLKNVAYFFATKTPVTRPSQEGDFISLSLYVSKRGDENSTPVAIFENKYFKISEEDMTDSFKARFLNVSTGHRVEEEIGSEDIQSFLNGDLLTFTVNAVIEISSPEMDDEKARQLQAESLEDLKKKLRIQLENQAKEAQHQKRFSDAEDALAQLIDFDLPESLLQEREELLSREKLLNARLVKYCSDSELEEQKQALLEEAKADARKAVKLLFLTQKVFSEKGLSISREELQYMMDVCSRERFGGYPPKDISNEMIQELVLVARDRLTYRKAIEAISSEKKDLEVVPS
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MQPGSGSFQPPTAAPWAGGAAPGPGAAVHGPISGPLGPPPAPLAGPLPVVALPHDFVLPQKRITSREGLETFARSHSGQLFLAFIASLSRAVEDRKLSDECPLSPTCAAIVGVLERLAAWVEDIPPAQQQARYGNPAYRFWQEQLQAHVGELHAAVLPAHLAGAAGELGPYLLDSFGNSSRIDYGTGHEANFAAWLFCLARLGVLTEADYPAIVLRVFNSYLSLMRTLQLRYWLEPAGSHGVWGLDDYQFLPFVFGAAQLTGHKYLRPKSIHTPDVLAQFQHDYLYFQAVQFVKTVKKGPLGEHSPMLNDISGVPTWAKIASGLLKMYRAEVLEKLPIMQHFLFGSIIRWAD
The following text describes a protein:
Function:
Transcriptional repressor that binds specifically to fat body-specific enhancers, namely the adult ADH enhancer (AAE) and the enhancer that controls yolk protein gene expression.
Subcellular Localization:
Nucleus.
Sequence:
MMHIKSLPHAHAAATAMSSNCDIVIVAAQPQTTIANNNNNETVTQATHPAHMAAVQQQQQQQQQQQQQHHQQQQQQSSGPPSVPPPPTELPLPFQMHLSGISAEAHSAAQAAAMAAAQAAAAQAAAAEQQQPPPPTSHLTHLTTHSPTTIHSEHYLANGHSEHPGEGNAAVGVGGAVREPEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNFCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEDEG
The following text describes a protein:
Function:
Cysteine protease inhibitor which inhibits members of the peptidase C1 family (By similarity). Does not inhibit asparaginyl endopeptidase.
Sequence:
MFFPIVWLSVLLIISKSFAREIRLSRATYNEDDEEIQEVAEKAMEQVNDQTRYRNLYKLVRVISAQTQVVAGIKYYLTILAAPTTCRKGAVGMNPMKCTIDSSKPTKQFKIEVWSAPWQNTFKVTLT
The following text describes a protein:
Function:
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Synapse, synaptosome.
Sequence:
ACPLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYTGELRLSVECANKTESALNIEVEFEYPFRLHQVYFDAPSCVKGGTTKIFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPMMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPMCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFMRAPPGAPEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPASGGGGYGPQGDYGQQGYGQQGAPTSFSNQM
The following text describes a protein:
Function:
Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MAAHKMSLTSLFFVSIVIVLSLFSGFGEGRYIKYRAIAKDRVPDCTQDPKNCVRVPVNQYHLPPGCQNTTHCYREKYHI
The following text describes a protein:
Function:
D-arabinitol dehydrogenase which mostly produces D-arabinitol in haustoria, the appendages of the parasitic fungus that penetrate the host's tissue and draws nutrients from it. D-arabinitol accumulation may serve as a carbohydrate storage compound. D-arabinitol is also capable of quenching reactive oxygen species involved in host plant defense reactions, thus providing protection for the rust fungus during the pathogenic interaction.
Subcellular Localization:
Cell projection. Note=Localizes in the lumen of haustoria.
Sequence:
MATQTLPAQMTALYYEKPRDFSIIKADVPLIDHDEVLLKVSMCGVCGTDQHIHEGEFIAKFPLIPGHEVIGTIVLAGNQVENVKVGDRVVCDVSETCHKCFFCQRGTPLFCESFEAHGVTLNGGFAEYAKFRAAKVFPIKNLTDEQATLVEPASCAVHGLDKIRPKPGSECLLIGAGPTGLMLAQLLKLNGAQRVVLAANKGMKMDIARKINAADEYIDLDRKDAANQWAQLKEDNPHGFDVVVEATGVESIVNDSINYVRRGGTLLVYGVYDNAARVTWSPTKIFQDEINIVGSFAQIHCFPRAVAYLESGKIRTDGMVTHVYKIEEYQEALDKMASRQCLKIAVKPN
The following text describes a protein:
Function:
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MEDRQTRLFLALILSMGIWMGVNYFFFPNTSTKKNTETKQTQSDKTSENTKQQITSGKTKESNSADPVVQKEKITPFDTKKSFIVTDSYIVEFSSLGGKISKFYMKDFTGPNGELIQVARKNPETVVVDGKSYQAVELSRDKGFDFNFSDSLVEISDSPWNYIQFSLTEDKINHSISFSAVSPDRSYQLKKEFRFYPSENYFKLSISIINFSKEKLSFASQKNVRYLRTFGSLGPYPKDRPLSDRDTANFFRFYYLGGSFQDTLDGSSSVGFWSSVGNFFTGNSGTDESFSIKTDKESGVDFAGTGSRYFIAVADPLDHKPHGIVLDNRPKNESGAVLVYDNILLNPGENYNLDFASYIGIRESEGMAFKNPELDPSQSKNSPFVGLSSDLNKSFNQGITTPFRNGIIWILKQIYRFTIPNYGWSIIIFAILFKLVFYPLNQKQADSMKKMQELSPQLKTINEKFANDPKMRQQKTMELYKKNNVNPVGGCLPMVIQIPIFIALYTAFSDTIDLWNSPFLWVKDLSEPDVIWTSPAIPYFTQTGIGLNLLALLMVGTQVFQTRMTSVSMDPNQKMLMYVMPVMMLYIFWNMPSGVTLYWTFQNVLSIGQQWITNHLKKTEEKKKAKV
The following text describes a protein:
Function:
As part of the small subunit (SSU) processome, it plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA. Activates BMS1 by promoting GDP/GTP exchange. Does not have cyclase activity.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MASQGNCLRYEGCNFFRHRIVLSTLSGRPVKIQGIRVKDESPGIRDFEASSIRLMDKITNGTRIEINETGTSLYYQPGLLSGGTLEHDCNIQRSIGYYLESLFCLAPFMKLPLKITLRGVTNDQVDPSVDTLKATAIPLMKKFGVDGEHFELKIIKRGMPPGGGGEVVFSCPVRKLLRPVQLTDPGKIKRIRGVAYSVRVSPQIGNRIVDAARSVLNQYLPDIYIHTDHLKGVNSGKSPGFGLSLVAETTEGCFLSAELTSNPQGQGSTVLPEDLGRNCAMLLLEEIYKGGYVDSVNQSLVLLLMTLGQQDVSKVLLGPLSPYTIEFLRHLRSYFQIMFKMESKTFEERKGAEKVLLTCVGVGFSNLCKPVK
The following text describes a protein:
Function:
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MHRRSSGSPVEDDAEDSPLVSRSPTESTAHGPNNNAFETAEKSRSQIAKRGTSFDLRRDNGASTPRSRNSGLWRTPSSSSTSSTTAMATASTETKSSSASFLMPLASQRLPMGTSPESSRFRSSRLRSPWTCSILTALTTLVASVFLFFIVRSFSARQAGEDGCGIPVMSPTFLHMVGFDTEHTRFASKYNLYLYREEGVDFYNQENLGLNGAPVLFLPGNAGSYRQVRSLAAEASRHFHDVVRHDQERIKAGTRSLDFFMIDFNEDMAAFHGQTLLDQAEYVNEAIAYILSLYHDPKRSRRDPELPDPSSVILIGHSMGGIVARTALTMSNYQANSVNTIVTMSAPHAKPPVSFDSDIVHTYKQINDYWREAYSQTWANNNPLWHVTLISIAGGSRDTVVPSDYASISSLVPETHGFTVFTSSIPDVWIGVDHLSITWCDQFRKAIIKSLFDIIDVRRASQTKPRAERMRIFKKWYLTGLEPVAERTLSQKEPNTLLTLEDKSNSILPQGQRLILRELGHRSGPKVYLLPVPPQGVSGKKFTLLTDQRFDKTGEHGNLEVLFCSVFPLQNGKFATVFSMNMDFSGGNTGSTRLACKNAAEDGIHLPASTPASKYPFDRVQPFSYLQYELEDLSEHQFVAIVDKADSPTKGWVLAEFSDSSDAVIRVRGGLGGLLSAGLKMRLPANRPMLTEIKIPALHSSLLDYKLQIVRHNHDKRQELFAPLLRQSISDPHESKFFVNVDKVDVNLHGVAPFMPPPLREQATLGGVSFQLWTDPSCGSTVDVSLKVDIAGSLGELVMRYRTVFAAFPLLVVALVLRKQFQMYDETGYFITFAEGLDTALRSSFPILLLAMSLLASSLATSAQIPPSDEPFQWPVNATETPIDFTKNDLLLGSQDAFFWFLVPVFGLISVGVCVILNYIALILLSVLSFIYGCLRTRSGYIKRNEKGTPIFSAPTARRRMINTAILLVLVSTLIPYQFAYMVACIVQLATCVRAQWHAKETRSTAHYNFSNYAHSIFILMLWILPINILVLLVWAHNLVVHWFMPFSSHHNVLSIMPFILLVETMTSGAMIPRVTTRLKHVTSMILFAIAVYSAVYGVSYAYLLHHLANILAAWFVVIYFFSSGFSLRRLWLILEGDDATQGKSEPGGSHQKKKP
The following text describes a protein:
Function:
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
Subcellular Localization:
Secreted.
Sequence:
METLGWSHPLTSVFVLSVAAFTPRPLRRKMWRSLCQSLLAVTFFGIVVGDLPVSPMDGPHSGSSTLEDRDLALSNTDFALTLFKHLKALEPGKNVFVSPVSISIAFALLSLGAKNATLAQILEGFRFNTTVGRAEAIHEGFHHLRRRLKASDAALDLGSALFVDEKIKILELFVTDATKYYEAEAHPVNFGDLEGVRKQINEYVANQTHGNIPELFKQLDERSIMILISYIHFLGEWIKPFDLKRTTEDTFHIAENLTVKVPMMFQFATFKHLFDDQLPCVVVQMEYKGNVTALFVLPDEGKMEEVEAGLSIDTMMRWSSSFDESQLEVYLPKFSISGTYELRPVLNKMGVRDLFSDRVDLSGLSEEKLVLSKVVHKAVLHVDEKGTEAAGATGMEIMPVMLPPSVTFNRPFLVLIFEDFTWSTLFLGKVLNPTEV
The following text describes a protein:
Function:
Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Note=Colocalizes with the tips of microtubule plus ends.
Sequence:
MANPVAGIAGSAAKSVRPFRSSEAYVEAMKEDLADWLNALYSLGLPGSGDGFLTGLATGTTLCQHANAVTEAARALAAARPTRGVAFQAHSVAPGSFMARDNVASFIGWCRAELGVPEVLMFETEDLVLRKNEKSVVLCLLEVARRGARLGLLAPRLVQFEQEIERELRATPQVSSVPAAEEDVTEIATVPGVPTRTPRMTPNDLRNLDELVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLEHYLDKHDPCRCSSSTHRLPQQRTGTFSPQRGSPTPSPRPGSPVPGSERRSSRPEVTPISLRGTKEGPETPLRPRDQLPPLPRSRRYSGDSDSSASSAQSGPMGARSDDSATGSRRERPSHRPTSCLPASPRRPTAPRSQSRDRLDRGRPRVAPGGRGAQLSTSSPARRTRSQSREEQAVLMVRRDRDGQHSWVARGRGGGGSGGSGRSTPQTPRALSPAAPRPSRGPSPGPELAATPASIFRTPLQLDPQQEQQLFRRLEEEFLANARALEAAASHTPMGSAPDPPAPDSAYCSSSSSSSSLSVLGGKCGQPGESGRTANGLPGPRSQALSSSSDEGSPYLAVGGALDATRSSLAGPEPSLTWARGRMDTQPDRKPSRIPTPRGPRRPSGPIELGAWHAQHSVTPRTEPDSSM
The following text describes a protein:
Function:
Involved in the biogenesis of the 60S ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTSMYNFKRITVVPNASELKDVVLSKTQRKTPTVVHRQYSIGRIRAFYARKIKFLQQTLHDKLTQIINEFPKMEEIHPFYSDLMNILYDRDHYKIALGQMNTARHLIDGIAREYVRLMKYADSLYRCKMLKRAALGRMVKLLKRQKSSFEYLEQVRQHLSRLPSIDPATRTLILCGFPNVGKSSFINNVTRADVEVQPYAFTTKALYVGHLDYRFLRWQVIDTPGILDQPLEDRNTIEMQAVTALAHLKASVLFMMDVSEQCDRTIEEQLHLFESIRPLFANKPVLIGLNKVDIRHRADLPADKAALLDQLEKEGIPIVETSTLTQEGIMSLRDRACDELLAQRVEAKIQAKKISNVEDSVLNRVFVAYPAPRDEKVRAAFVPPGLAAKRAAKKLAAENSMEVDEVTTTKAGSIGEFRDENTRRLEREIELAMEDDYILDLKKQYLLKNPDEKYDIVPEIWEGHNLADFVDPEIQSKLESLLKEEELLEQAGEYESDLDSDDEETKEKMSLALQIREKEKLLTLEHAVNKRIAGRVGSRVHTRKRERSMSRLEQELGDLGVDIDTKKMKNLQGQCAKPQLGKKMKVGRSRSLSAVRPAPRDEIAFPDEEKRAHVNKLRTKAMRGLRREAKKGEADRHVYDLKPKHLFCGKRGNGKTDWR
The following text describes a protein:
Function:
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
Sequence:
MAIEQMTMPQLGESVTEGTISKWLVAPGDKVNKYDPIAEVMTDKVNAEVPSSFTGTITELVGEEGQTLQVGEMICKIETEGANPAEQKQEQPAASEAAENPVAKSAGAADQPNKKRYSPAVLRLAGEHGIDLDQVTGTGAGGRITRKDIQRLIETGGVQEQNPEELKTAAPAPKSASKPEPKEETSYPASAAGDKEIPVTGVRKAIASNMKRSKTEIPHAWTMMEVDVTNMVAYRNSIKDSFKKTEGFNLTFFAFFVKAVAQALKEFPQMNSMWAGDKIIQKKDINISIAVATEDSLFVPVIKNADEKTIKGIAKDITGLAKKVRDGKLTADDMQGGTFTVNNTGSFGSVQSMGIINYPQAAILQVESIVKRPVVMDNGMIAVRDMVNLCLSLDHRVLDGLVCGRFLGRVKQILESIDEKTSVY
The following text describes a protein:
Function:
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
Subcellular Localization:
Cytoplasm.
Domain:
Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex; The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.
Sequence:
MVRAKLRELAYVTQQRANEPVCCTLFDPLLDLLWTASSAGSLHSFICPTLDKYSFFGAHPSAVVGLLGAAEGILSVSSEYVRMHTRGGVSLMSFRDDDVLGITCCDWERPGAGRVLIGHSGSRLSVLDLSTAYIASSVVVGQDIAVMRSNGRLVACGGMGGDIILKDFRTMKTEHTIDAHPGKVSSLDLKGDLLVSCGLTRRMGRIYCEAVIKVFDIRQQARPLSHIPFSPGATILRFQPKFSSIVLATSASGAILLTDVQGVGADVQSYQVDCESDHLLSTDVSSSGELLAFGDSGGYVHVWGASEHDLVNLHSLPTELPDIVQPLAENHVCELESFSDVFLPATTDVPFSAMDMSTPIRVGLPPRIVGKHLLEQMNAHDFVGYVPNPYWRRGSSQGSASRAVAGIRNLRQTPKIDVKPQSTPVQRPGVSVFTTKVTTKSGQSWLPKTYRRVEIKQSQYKLKYEEFDFSYYNKTRFAGLENDIVNSYCNALLQVLYFIPALQAAVTSHVCEREFCLTCELGFVLHMLDVAQGGTCQPSNLLRALRQIKEAAALGLVEGPEEWENSKEKSLAKRIQSFSRFLLEQIHKEGAGSMDPEVPSPLPSISNQLFGMVIHVHSKCRGTSHEDVVQERLSFQVDLQYPAGKPNSVRPSFAELLQNSLCKQEDMRAWCPHCRAYVSLQQTRFPCSLPEILIVNCCIQREADLYYWFADGDYPPTSDSGKTGISNNGSNSTSSGGQVVRSNWLPFRVEIAVDPAASSVTVTEGGTEDSKDVGKSKESVVAESAETTTSTRAVYELTAMVAHVHDEFDKGKLFQEESEGHLVAHIKIPSSYSDSYGGISLSSPGPGVNSSTAFSKLQLEPTPVGLGGASTTSDWVLFNDFCIAPTSASDVVTLYGKQKVPCLLYFSRVKEPVVDSSNHTTQSLPAGSLTIQPSPAGFQGRSHGTPISDEIFKRLILETRASLDSPAAVSNPYTTFLPFDMTTEFPKPRMLLGLDAEFVALAPAEKGIREDGVEYVKRPARLGLARVSVVRGEGLKAGVCCIDDYICAVEPVYDYLTRYSGVAPGDLDPATSKHPVTTLKKAYVKLRYLVDKGCRFVGHGLKKDFRMINIVVPQAQIIDTVELFHLKRQRMLSLRFLASYLLNTNIQNETHDSIEDACTALRLYEKYKQLVAAGEFHDKLLEIYRYGRKYNWEIVKDVSEESVRADPTPS
The following text describes a protein:
Function:
Increases the platelet count associated with splenomegaly. May have an important role in neuronal precursor development and maturation.
Subcellular Localization:
Secreted.
Sequence:
MYCLLATPLCLLSLLLPPLSPAAPISPSEPIGQAYSLALYMQKNTSALLQTYLQHQGSPFSDPGFSAPELQLSTLPSAAVSFKTWHAMEDAERLSRAQGAFLALTQHLQLVGDDQSYLNPGSPILLAQLGAARLRAQGLLGNMAAIMTALGLPIPPEEDTLGFVPFGASAFERKCRGYIVTREYGHWTDRAVRDLALLKAKYSA
The following text describes a protein:
Function:
Plays a fundamental role in microtubule-organizing center structure and function.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MVKANDKKLTDDQITEISEAFELFKNNEGKIDIDQIKYAFRALGIEEPTKNIVKNNQKSITYNTFLELVSPLIPKRDRLSTLEQAFKLFDKDDSGKITFEDLKSVAINLGEECTDKELREMIQYADQNDDGAVDKDDFFSLMTVGKKIL
The following text describes a protein:
Function:
Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).
Sequence:
EGPPTMPVKLAANLSTMFKDGSLADRYSTALQMGFKAVECQFPYDTPLEEIRSRKKSSGLEQVLINSYPGDLSKGELGFAAKPGCEGEFLRSLETTLNYAKALNCNKVHVMAGVTGGHCDKSMEETYVKNLRKAADMFEKEDIVGVIEPLCKQVKPGYFLDSYEKDLEHPSVIVLSNISLQDVFHMQMLSGNLTNTIREIFPLVGHVQVSQAPNRQEPSAPGEISYRYIFELIEELGYRDWIGLEYFPSGSTADSITWIKDYGYVL
The following text describes a protein:
Function:
Catalyzes the exchange of ADP and ATP across the membrane.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MEMGKNKSEKFSMDFVMAGMAAIVSKSTAAPIERVKLLLQNQGEMIKRGQLHQPYNGVGDCFKRVLRDEGLFSFWRGNQANVIRYFPTQFAFAFPSIELSLSNIQRTSKPVKRTSFCICLAFSHLSVVFHLSLHSHHFPPKGEDLIQGLLEKWSWRLGFTMEPEHQKEKENDGKKVWSCDTQEKVGAAMVKIVRGEKQKEDGVVSSGWCMLAFNFAFKGYFKSIFGHSKEKDGYMMWFAGNVASGSAAGATTSLFLYHLDYARTRLGTDAKGCSINGQHKFNGLFDVYRKTLSSDGIVGLYRGFGASIMGITLYRGMYFGIYDTIKPIILVGPLEGNFLASFFLGWSITTVSGVCAYPFDTVRRRMMLTSGQSIKYRSSMHAFREIVHLEGFTALFRGVTANMLLGVAGAGVLAGYDQLHRLASRQGYSFESYQGALK
The following text describes a protein:
Function:
Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases. Prevents root growth and seedling development in heterologous system.
Subcellular Localization:
Secreted.
Sequence:
MGVPSGLILCVLIGAFFISMAAAGDSGAYDWVMPARSGGGCKGSIGECIAEEEEFELDSESNRRILATKKYISYGALQKNSVPCSRRGASYYNCKPGAQANPYSRGCSAITRCRS
The following text describes a protein:
Function:
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
Sequence:
MASTVFLSTFSSAHLSSSFAGDYVASSRCFIGAPVASSSSLSLLSGKKNSYPFRKFHVSAKKVSGLEEAIRIRRMREAEATSKVKRNPPLRRGRVSPRLLVPDHIPKPPYAESGVLPDISPDFQIPSPEGLVKMRAACELAARVLNFAGTLVKPSVTTNEIDKAVHDMIVEAGAYPSPLGYGGFPKSVCTSVNECMCHGIPDSRQLQSGDIINIDVTVYLDGYHGDTSRTFFCGEVDEGFKRLVKVTEECLEKGIAVCKDGASFKKIGKRISEHAEKYGYNVVERFVGHGVGPVFHSEPLIYHYRNDEPGHMVEGQTFTIEPILTIGTTECVTWPDNWTTLTADGGVAAQFEHTILITWSGSEILTIC