lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Metabolizes sarcosine, L-pipecolic acid and L-proline.
Subcellular Localization:
Peroxisome.
Sequence:
MAAQTDFWDAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPHSRGSSHGQSRIIRKAYPEDFYTMMMKECYQTWAQLEREAGTQLHRQTELLLLGTKENPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGEVGLLDKTGGVLYADKALRALQHIICQLGGTVCDGEKVVEIRPGLPVTVKTTLKSYQANSLVITAGPWTNRLLHPLGIELPLQTLRINVCYWREKVPGSYGVSQAFPCILGLDLAPHHIYGLPASEYPGLMKICYHHGDNVDPEERDCPKTFSDIQDVQILCHFVRDHLPGLRAEPDIMERCMYTNTPDEHFILDCHPKYDNIVIGAGFSGHGFKLAPVVGKILYELSMKLPPSYDLAPFRMSRFSTLSKAHL
The following text describes a protein:
Function:
Transcriptional repressor that negatively regulates neuron differentiation by repressing retinoic acid-induced gene transcription. Binds and interrupts RARA from binding to retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. Recognizes and binds 2 copies of the core DNA sequence 5'-CCCCCA-3'.
Subcellular Localization:
Nucleus.
Sequence:
MEETSLCLGVSSAVPEADAHLSNTVLNGQYPISQKLHQLTAQLGHAFPDLQNRQIPEEKAATPLDEKSHMALASQPLSSQMALLANQLNRDIDTSLSMNGRVDLQQFLNGQNLGIMSQMNDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRDKQMKSSLLQPRLDIKQQPQPLQHQHLPMQTQQQQQAPATASGLLTPTGHSTPETLSQPSPSPKPASAQEEQAAPPSGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQEEDLISHVEKAHITAESAQGQGSSGNGEKPASEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSIKNKSPSDSEVPISMNNMAHEAHANLYSRYISCLQSGFLSPDKAGLSDQNQMLTKAGIAMKEKEMLGKLLAPVASMGHNLPEGEKRSLLGCLNLVPPLKSSCMERLQAAAKVAEMDPLNSYQAWQVMARGMAMDQAFLPKEQHQVPHSQEEAMVNAGLVFAKEKHEYLVVAADGSKQKLHAESVQCTKSSNLVSCKDDTYDNSREFMSHNIGQSLEYMKEKPTECPDCGRVFRTYHQVVVHSRVHTRDRKQGEEGIHGCLDERRGSASDPESQSISRSTTPGSSNITEESGAGGGLSQTGSAQEDSPHPSSPSSDAGEEVAKPMGVQQPSLVRDRGLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHREQQNGGGPMSGHSQEHKEDHSNAKGSMFIRPDILRGVFKGVPSTDFRGGQLLPHQWASGMISARERHGQCASVASENSLENLKSSEASGEGTPSFSDLGRAYQSMVGNGVNFQGSLQAFMDNFVQSSLKKEKEMREKPFSESIETKAKRGENSVEKADAKPSEGKPEKSQYEPLDLSVRPDSASLPGSSVTIQDNVAWHGCLFCSFTTSSMELMALHLQANHLGKAKRKESILDMKGISKEQTGELASLNKASLGTSASHLGKEAISSKQSPHIDKMTQQETVKETLGEQKSSTWPNHMDANVSSVQNDFFKQFRIYATSGGSGTQSSSNTSQEAEQNIQPADSINLKSASLTNRGTTDELSDKVSSSEMEASEEHEQLEDDGRPAEHSDDSPNEKLESDEDEEEEEEEEEEDGSRDLMQSGIPVKDSQGLVPTMPQLLEKQWQGLNLLSSQGVPPGVMKPEHAHLEQQMNMLSVLRAYSTENLAAFNGLGNSSNNTSGIKRPDMPGQRPFQCRYCPYSASQKGNLKTHVLCVHRMPFDNSQYPDRRFKRSRVDSDTSGNSEDANAMTPGSAGESAPEAGVQE
The following text describes a protein:
Function:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.
Subcellular Localization:
Chromosome. Cytoplasm.
Sequence:
MPRVANPKHRRSNGASTPHKNSPMKIPLNDDTGEKAARLEARQARHDRQMDQIKAAVKTPMPPRRYTYDRASSMSPGTPRGSGHRRRESDADGRRAVTPMKRVPILANFEEWMKMATDNKINANNSWNFALIDYFHDMSLLKEGDGVNFQKASCTLDGCVKIYTSRVDSVATETGKLLSGLADSREKRGRDTGAEGEGDDEDDEEGEDGTARKSRRKAQRTHEATLAPSFAALQLKKFELEFSVDPLFKKASADFDEGGAKGLLLNHLSIDGQGRIVFDSSDDAVEESPNDVDNSREGSEDPEHPKSSSPAPKRSSDDAFEDVEIDITPLANQFFPDLTRLDEQDICPSLKNFDLGDPSGSLDIPFLKAPEEWRNEKGNEDGRGGNDASGIMLDDDNAVGFDDDDGTLAGFDLSEDAGFGNGGEAWAREAALEPMLKVHRIDRDGDQNQDGGEAMDDEDGYAISLTHQPDKRDHENILSYFDNALQKNWAGPEHWKIRRIKENAAASSATAAPKQRKEKEPFEIDFAAPLDPTVAELIYTPASSNSTISLPKTQWKTKGRNLLPDDKHFNSRQLLRLFLKPKARMGSKKLVGLRQFNSRRQDRTAVNGEMDEAFWASRKQEEEAAADEDAAPGAYDADFFADDDGLAFPNGLGMADDDDDNLPFTDAREMLSPPADGAPGTTAGDAGGATGIAALLNMVGATPKPGAGGFGSQLVTQGGRRARPEYVAYARVAKKIDVRRLKQEMWKGMGERLIASTQFDSMTQASAGNGVNQVLNTETEPDAPPTPTPQRPQPVDSSEEPKEDRRLRFTQVMNSLKTVYPPEKLRDISTSFGFICLLHLANEQGLILQNDGLSEGAGAGSLEEIYIAKDVNAVIDEASA
The following text describes a protein:
Function:
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
Sequence:
MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASAIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.
Sequence:
MNFGGMMGGGATPGAPQQPSQQSQLMMAKVEMASYADLFERLSRVCFQKCKFKYNDGQLNVGEMSCIDRCAGKYMQAYSSLGVKMAQVEKEIMDQAGASAGVQQ
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein.
Sequence:
MAETLRLAVAVIGNVASVSLYAAPIVTFKRVIRKKSTEEFSCIPYTIGLLNCLLFTWYGLPIVSNKWENFPLVTVNGVGIVLELAYVLIYFWYSSSKGKVKVAMIAIPILLVFCAIALASAFAFPDHSHRKQLVGSVGLGVSIAMYASPLVVMKKVIQTKSVEFMPLPLSLCSFLASVLWLTYGLLIRDIFVAGPSVIGTPLGILQLVLHCKYWKRKVVIEEPNKVDLPKLVSLENLDLEKGGLEKGNLEKNVTTS
The following text describes a protein:
Function:
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular Localization:
Cytoplasm, cytosol. Rough endoplasmic reticulum.
Sequence:
RLPSVKDFSALSKDACTPEVIFGFQGRGLVSTGGVQRPVKLPGWSAVSGRFRSSPRGRSEKEGREGASEPGSLLIPSGGSLLPQVSQTSNMQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEVDKVTGRFNGQFKTYAICGAIRRMGESDDSILRLAKNDGIVSKNF
The following text describes a protein:
Function:
Rhomboid protease that catalyzes intramembrane proteolysis. Required for transcription factor srbA activation by mediating its release from the membrane and thereby regulating its activity under hypoxic conditions. Essential for iron homeostasis and resistance to azoles such as voriconazole. Required for virulence in murine models of invasive pulmonary aspergillosis (IPA).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAIPAALPPLPFNPTRVRSYMLRLPLFTRLVLLVILAFWLLELQTIWSVVQWGSLTPNEIGIGSMYRLNTYPFIHVGFFHAFVNLLALTPLLERFEAEHGTLTAVALFIGPLSTFPAGIYILVEKFILRSNTAVVGASVWIFLLLGSEAIKTFKSNPYFSLGTTKIPTWTSPLFACALVSIFVPNTSFLGHLSAIIIGYLLGLGYLKVFVPPEKILRWIEGKLNLLGRLPHYVSVDQKTYGRYGVLPTATAAVGGERPTPLSYLGTNQRLGP
The following text describes a protein:
Function:
General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. Binds single-stranded DNA (By similarity). Binds specifically to the NssBF element, a short nucleotide sequence of the 1731 retrotransposon, to repress promoter activity.
Subcellular Localization:
Nucleus.
Sequence:
MPKTKKKDSSSDSDSGPDDRIKPASKKAKESDAPNSDPKDSGENGATSWTLEGLRQVRINEFRGRKSVDIREFYDKGGQILPGKKGISLSLIQWKKLLEVAEEVTRAIEN
The following text describes a protein:
Function:
Component of the positive transcription elongation factor b (P-TEFb) which consists of cdk9 and pch1, and which phosphorylates the C-terminal domain (CTD) of RNA polymerase II and spt5.
Subcellular Localization:
Nucleus.
Sequence:
MKRSSSVSVEDEKSARRKLDVVPKLHFVGCSHLTDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKHENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLFAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRREYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRLCGSPTQATMPNWEKLPGCEGVRSFPSHPRTLETAFFTFGKEMTSLCGAILTLNPDERLSASMALEHEYFTTPPYPANPSELQSYSASHEYDKRRKREQRDANSHAFEQTANGKRQFRFMTRGPSDPWYGIRRPNYNSQPQYQRGSYNREGGNMDRSRNVNYQPKRQQNFKPLTSDLPQKNSEFSETNAMNQTSNHSHADGQRYYRPEQDRSQRLRNPSDYGRQGRQSSQSQQPAWNVSSRYQNNSKVQTTSRASENADTNKTQHNIKYIDSYVPEYSIARQSANQKTNEQHPSSTSLHQQSTSDLKSPSFHENSNVDDTPK
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MKHRPVHERQSSTESKNLKETTQLIMQSSSDHTHHQLGSNDSPSACMSLPVPQLSAEGSCTVGDVTVDLSSQDSQHVARSNSRRVRPSTHGRSPSRHGHTHSHDASGPEDANDDSREQSNSISEVFHLYKWLEKSFPYILIFSAKLVVQHITGISVGIGLLTTFLYANKCIVNQVFLRDKCSKLQCLWVLVFLLFSSFLLYYTFSSQALYYSLVFMNPSLGPLHFFDALWVVGITDFIGKFFFMGLKCIILLVPSFVMSHKSKGYWYMALEELAQCYCTLVSTPVWFRYLIDYGNLDSGAEWHFGILLALLYLILKILIIFGQRKTSSDCLRLFLSQPNYGTTATKRQCSEADGMCAICQAEFTKPIALICQHVFCEECISSWFNKEKTCPLCRTLISNHSHKWKDGATSLQLRIF
The following text describes a protein:
Function:
May be involved in vascular wall and kidney homeostasis.
Subcellular Localization:
Secreted.
Sequence:
MKYSIVLALAVAMVGAVPREGFGPGMQDWGFAEVRPGAHMFWWLYYTTADVPNHADRPLVIWLQGGPGASSMYGNFEELGPLTLELEERNHTWVRDYNVLFIDNPVGTGFSYVEDFSLLTKTNGEIADDLVELMKQFYDAQPEFRNTPLHIYAESYGGKMAPEFAYVLDKAIKNGEIECNLQSVGIVAPWVSPIDSVLSWAEFLLNMGYVDTKGYNAIQASAIETEHVLNQGQWEQATNLWGMTENVILRETHGIDFYNVLFKQDFAGTRSQLEQFSRDMRSAIASRATRLASEDRDQILQDLMRFEVAPALSLPAESVYGAQSGRVFNTLAGDFMKPAIDVMELLLNNTSLDVVIITGQLDLIVATPGNVRWIEKIQWSGRNNYLQSPRNAIGQHGVLEGYEKSYGKLAVYWALRAGHMVPADNPILMDLILQKHVPVQ
The following text describes a protein:
Function:
Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose.
Subcellular Localization:
Cytoplasm.
Sequence:
MASAKIEKSLYGQTKAGKDVYKYTFTNMNGVQVEVISFGAIIIAVKTPDRNGTFEDITLGYDDIKGFEDNPPYFGSTIGRVANRIANAEFTLDGKTYHLAKNNGPNCLHGGLIGFNKVLWQSSIEEDHVKMSYTSHDGEEGFPGKVKVTVTYSLTEDNEIRINYSATTSKATPINLTNHSYFNLAGQVAKDVLSHVMWIDADKYLPTNKVQIPTGEFRPVTGEPEGAFDFTKPKAIGKDIDKTPPGYDHCFCLNQGEGMKARVVHPESGRVLQIFTNQPGMQLYTGNFLEGNTGKAGLHYHKHDGLALEAQDYPNAINEPSFPNTVLRPGMEYKRHIIFQFLVEK
The following text describes a protein:
Function:
GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Sequence:
MFSYSQAIRFIIFLLPICLTFKITENRIDRGKLNFEIQDITIKSGAFWSIVDNSICTFFGSLMVEPQASLYVSSTSPILALQVAFVSILGVFHNQGNITFDSSASLTSATYRIITSTFRNTGRMFFSASGKFPNTMDIVASDWTNNGLLSFHQDQRTSGVVSLGSALGTITNNGQIKLSNQVYQQRTQISGSGCFVAINNSTIYISNSLLPVQITQSFYLADSTSSIIVDSFSATQTFNVYGFGNGNMIGLTLPLVGNYWYSSYTYDATTGILIMRNVFLEQKFNIGLGYNPSLFKIVTDWGAGIPSTILGSLSYSGCVPSRRLPSICQIDPISSLEIPGTKPTQFTSVFVSTDDSGRNGQYVGLFEVATNKNYEWVSAVIIITSIPTVTIELPPTLTLEAQWLPTVSGVLHTSSTITQSTKIGLLTTVSLVPVAETQLASRTFSIVGPPIPDTTSLELVVPTKSETRVVTESTVVPVLPPKVTHFTNSSTSNRRYSSESMVDEEFPSEPFMSDEVSIEVYESYTDESCVISTDFSVDVDYSSDLSMNFQTYDTLDTTEMFNTVENFETYDTFGTIESFDIFETSQTFESYETFNETSDLSMFSLTSESFSDLPPPLVQTDTPVSFNPVPSRTNMSEKTIMWEVTNSQGSIITESGIILISGEYQTTVTTFLRDLDQMEGYTKYTKTWEVTNSNGSVVTESGIIDESGSYHTTVTTFPQKDQNWEWAANTVEYTKTWIVTNEDGSIITESGIVGESGLYQTTVTTFPHELSSFTIYQSEEAHSPGVINAGDIESTPLATSSSIYQSVIIEDEFPSSPGNTYTDVFSPTTGHDLDLPDDTTFTPSQSSSTTVPIESEYISESIILDAGSSVSTMISPTTLTTNFPIFDSSDNQFKHVSLWDSRVSSRSIVIVSSEFPESDAPLILASPNDGSSNQTSTTASITVNDNQNINNPEFQQGEAVISSSIDSSVSHLYYISEETSIASNNGDLSDDLEVDFILLTSLHDTISAKATSAGYSWKFYPESDEIQIDQTGDYNYSLAGAKTHIHESAYTQQDASTQKGASVQQETSIQQRVSTKQETYTQEGTQQVTRTQEKVQQGASHSTTNSHFEGTFISKTASPTNNDFTLSFEPKDNATDISNSFFAHLSIVGNSTVFETDYTDFSFIANSNTFKSDANGVDSTSNQTYSAGVGGSNVSGLISKSESVVLLIRPVMIFVFLAICVVIML
The following text describes a protein:
Function:
Effector protein involved in gene-for-gene resistance in plants expressing RPS2. Its thiol protease activity is required for the degradation of plant cell RIN4 and consequent activation of RPS2 during bacterial infection. The activation of RPS2 is sufficient for the induction of hypersensitive response (HR) and plant resistance. Cleavage of RIN4 by AvrRpt2 also interferes with RPM1-mediated resistance activated by either AvrRpm1 or AvrB. Contributes to virulence in plants lacking the resistance protein RPS2 promoting pathogen growth and disease symptoms. Inhibits PAMP (pathogen-associated molecular patterns)-induced signaling compromising the host's basal defense system. Blocks plant callose deposition, flg22 (a peptide corresponding to the most conserved domain of flagellin) induced accumulation of PR-1, PR-2 and PR-5 and activation of GST6 transcription. The mechanism of virulence is unknown, but this activity is independent of ethylene and salicylic acid response pathways and independent of RIN4 disappearance.
Miscellaneous:
MISCELLANEOUS: Only naturally present in strain JL1065; MISCELLANEOUS: The C-terminal cleaved product is sufficient to trigger the RPS2-dependent immune response.
Subcellular Localization:
Secreted. Host cell membrane. Note=Secreted via type III secretion system (T3SS). Localized to the plant cell membrane.
Sequence:
MKIAPVAINHSPLSREVPSHAAPTQAKQTNLQSEAGDLDARKSSASSPETRALLATKTVLGRHKIEVPAFGGWFKKKSSKHETGGSSANADSSSVASDSTEKPLFRLTHVPYVSQGNERMGCWYACARMVGHSVEAGPRLGLPELYEGREGPAGLQDFSDVERFIHNEGLTRVDLPDNERFTHEELGALLYKHGPIIFGWKTPNDSWHMSVLTGVDKETSSITFHDPRQGPDLAMPLDYFNQRLAWQVPHAMLYR
The following text describes a protein:
Function:
Has antibacterial activity against the Gram-positive bacterium B.megaterium LM101.
Sequence:
MKFFALFSFFVLCVALATAGHLGRPYIGGGGGFNRGGGFHRGGGFHRGGGFHSGGGFHRGGGFHSGGSFGYRG
The following text describes a protein:
Function:
Required for 60S pre-ribosomal subunits export to the cytoplasm.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTDYTLIQHKMKMDPPAYEDDFKRYYSHFKSSVTTMLAQAELGMSVPDTALDETLRLVVFLNNISAEYKKYLENFPRELIEMIKKCKLNSQSKVTITKALIGLRSKGFMSLEEILPTLLEMLCIKDKNVTAIVYRFIINDIKHTSQQKGGAKSKQSTMRLLEQIIDSNTNIKVVKKVVEILGELFTRKILKEPRVINILANAIFHNDAKVKVKAMEFFLRLDEKQAAMDDETKEELKQAEEELRLLKKKMGIKKRTGKLRAMKKEAEDTVDKLRKTEVIAHQANWAAIDNIYDPIAFCDKLFRDIKGSRNRFAVRLMELDLLSRVIARREVICLPFYSFIVRYLYVRHENITQLLAYTAQAIHPLVPPDAVEPIVRTILNNFVSDRSRVEAQALGLNTVRTICERCPLVMNQSMLKDLTMYKKSHNKAVVSAARSLISLYRGINPELLSKKDRGRPDQQHKTILQYGEQKVYDGPIGAELLEKKESSDDNMSEEEDDNGVQEEMNNKEEDMNKEEDSPNDGDADECSSDEEIDDNLELGSSWEECSDSSDSDEQEEEGMSEEEDEKEDNGKEEDEEDEMSEEDDNVPQYDGGLLTQEQLEKIRRKQREDEGISSSSEEEMERDTTYVLPESLEASVKKKLSRDERIKILKESRAENEKFHRNRTGRTSKVLARNKPFLMKSFSKKQMKKEEDRITGGKKRVPRKQFSGKIRKRFGKSGLKQKSNGGSRKK
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MFLGNAAVFEGQCELIPGCEPMNVPFPRLSCLSLQIPVTFEDVTVHFTLEEWDSLLEWQQALYLEVMEANFELVASLVQAGSVPHTPELIGKTEQGDEPWAPGPQIPGSEEDQGNPGSGHGGGAQEVRVKEEPGLIWDLPSSSSSWGSLGCSPLPLALCPSWCQVKLTDVRSLSPEALLEATEGSNHQAQLLICRECGKSCADEESLRWHQWMVHEVRKEEEDEEEEEEEENEEGAKEVVDRKGPFACTSCGKVFVHRRNLLAHKKHRSKRRHDCVQCGAHFCLRGDLLRHRGDHAGEGPHPCGTCSLVFQHKRHLDAHKAEEHSAAESEPQRQDPRSEDGGGEEGDRPFDCPTCGERFSWRESLQIHQSTHRPEQAFQCALCGRSFSRRRNLLAHQRIHTGDRPFACLDCGRRFVTNSGLAGHARLHRRQQPFLCRHCGRRFRHREKLLEHQAAHVAQAVEEEPET
The following text describes a protein:
Function:
May play a role in cellular stress response.
Subcellular Localization:
Cytoplasm.
Sequence:
MNFDYDAKILKNSILTQISEPVVFKNLISDWPSLKWSFENFDEIFKDVLFDFRIGSRNIDKINWETNCPHIKASAGQFKNWISKNKNINEKKNNDRLENNNSNNNNNNKDNCGDDNPLNSVDPSTHWCYADYKHMCKLFDDDDDDYDDDGDGDGDDDDDDGGGDNDNEDNKDDKSVNKRNKFDPNLKEKILASIDWSKFGFEGRAGLESTLWIGSREASTVCHYDTYGCNLVAQICGRKLWVLFPPTAAAAATTTATAATAVNAMYSTRIPYEESSYFSTINIGCGSYDGYPNFKRSAIPYMVILNPGDVLYVPKHWWHYVQCLEPSITVNTWIELQSDHLDRVKESIVRCAVYKFLNNNNNNNNNNNNNNNNSNNNNNNNNNECHFDDDDDDDDGDDDGNDRRPWLNPHHHHHFL
The following text describes a protein:
Function:
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRPTSMENTTTTNSSPLPSSEPHLVRGVWPYSMTSVWCLAAIVGFLIIFTIVGNVFVVIAVLTSRALKAPQNLFLVSLASADILVAALVMPFSLANELMGYWYFGSVWCDIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRIKGIIVTVWLISAVISFPPLISMDRDTEDHVYPQCKLNDDTWYILSSCIGSFFAPCVIMILVYIRIYQVAKLRTRTLSEKKPTRDGSSHTENGFSKGTSVKMPGDNKENGHCPSRPSPPKATDVDDVELEESSMSESKRRKSSSKEDNTDSSKERKCSKGNSFSKQSSRLSRSSNKSMELFSSRNKKKRCSVSRRKLSQAREKRFTFVLAVVMGVFVVCWFPFFFSYSLYGICREACEVPETLFKFFFWIGYCNSSLNPVIYTIFNQDFRRSFKKIICMSRRKTITH
The following text describes a protein:
Function:
May be involved in plant development processes.
Sequence:
MKEEPEREEFRRKKVSHHSQSIASGSRGGAPFFAFSPFLFFPGGAIIKLKTVAFKDFDCYLRRRRMGFRPRYEVLEQIGKGSFGSALLVRHKQERKKYVLKKIRLARQSDRARRSAHQEMELISTVRNPFVVEYKDSWVEKGCYVCIVIGYCEGGDMTETIKRACGVHFPEEKLCQWLVQLLMALDYLHSNHILHRDVKCSNIFLTKEQDIRLGDFGLAKILTSDDLTSSVVGTPSYMCPELLADIPYGSKSDIWSLGCCMYEMSAHKPPFKATDVQTLISKIHKLIMDPIPAMYSGSFRGLIKSMMRKNPELRPSASELLNHPYLQPYISMVYMKLESPRRSQWCETKERRRSFSSNDRRLNPSVSDTEAGSVSSSGRASHSPMFRRRKVSEVTVGVVSEEIVAQREEGVVKKQSGAAAKTPRMAGTSTKQPKRLETPSSTPRTVQLTDRRRRASLPLVVENPYACESDISVNAPRFDKIVEYPEDLFQNRETTSSGGVARRSSFSSMTTTKDKCTTTVQTRSVSEVKQRRFDTSSYQQRAEALEGLLEFSARLLQQERYEELGVLLKPFGPERVSPRETAIWLTKSFKEASV
The following text describes a protein:
Function:
2-oxoglutarate-dependent dioxygenase involved in glucosinolates biosynthesis. Catalyzes the conversion of methylsulfinylalkyl glucosinolates to alkenyl glucosinolates.
Sequence:
MGSCSLQLPLINLADKTLEPGSSKWAEVRSDVRKALEDFGCFEASYDKVSLELQESIMKTMEELFALPVETKQRNVCPKPYVGYLNHNNLSESLGISNANILENVNEFTQQLWPDGDGNENISKTIQLFAEKLVEIDVMVRRMVMESFGIEKYIDDHLKSTEYRMRLMKYIAPPEGDANTTVDDYADLLAKLNIDGVEPNVGVKVNADISDDVNANPSVNAGVGANVNADTGVNDNLNVDAEANGDANIAVGGGVNANTDLGVGVNVNSNVAVNAKTGATSGDDVEANDDNEEKKLGLPCHTDKNLFTVLFQHEIEGLEVKTKDEKWIRVKPSPNTFIVIAGDSLCALMNGRIRAPYHRVRVTEKKRTRYTAAIFTCPKPDYVIEAPKELVDEKHPRLFRPFDYRDLFTFYHSEAGRKIQYTLQAYCAVSEA
The following text describes a protein:
Function:
Responsible for addition of the terminal mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose. Implicated in late Golgi modifications (By similarity).
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MIEKLTIKRSRQKVIAYSVIIIWLMIVNIWLLNNYHLNSSTLTRHGNGDNLIDEDDDSSSSSEYSIYNELDTENYLGQQHQEEDVPNSQSTDNSLIKPTSPAKNSFKDDITIKILQKHLQKQQNNPKDIRTKDSHAEIYNQIFENHPQIDTILGNLNFNQRCQLFFQNLFIKDNNWILNVKDKKIKLENKNDFKFNDFKKSHLNEFKRQFKTMKKLLEPNKIIHNKDFDNSIEFQDFIKMKYEQFWNRTMTYEQKIVDSISILRIFNKCYLIEEATSTTTTKNNKQDFIKDQFKLVDGIRRASKKNPSLPKFKPTKQEQMVNFDNENLSPSILEHRVYPWLSFEYPVYERWTGKVQYQPPKMANYVKDGNQKTTKKTKYNNDKYLSSFFLNRLKQKCNGRGLVLSISDLHVDVTVRLIHLLRALNNRYPIQIVYYDNLSKETKEKIVTAAREVMSHVPKSFERVAKYFPDDYLDNDQGGLPKQEIWFINTYNVIHADYKLQFRGFANKFLATLFNSFDEFILLDADTVLTQSPSYFFNLPQYLETGTFFYKDRTTYETRPKSDSIFFEKLGPSVIDSVMFNIPIMTSYTLNRSFFKGLFHYMESGLVVLNRDMHYSSFLTMVQMNFFEPVNSRIHGDKEIFWLAMAINGKQNYYFDENYAAAVGVMTPDIERTKPDKTLHESKELCSPHPGHISHDDNSLVWLNSGFFYCGQNDKVKFVEEFKHKSRLKHLNTLEAFKTFYYSPLRIENAIIPPMDLDIWAANNEDEPAKGWFGDPRYCSGYMWCAYDKIGGKTKSGKNTRLEGKIINFDEQAQDLFNYYGDVWVGME
The following text describes a protein:
Function:
Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway.
Sequence:
MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNKSEQEGTEVGQTLWLTTDVARQFISILEAGIAKIESGDFQVNEYRRH
The following text describes a protein:
Function:
Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.
Sequence:
MKKIINNPQNVVSEMIDGFTQSSRDLLKLKGNFNVVVRSDYSQIKDRVTLISGGGSGHEPAHIGYIGNAMLTGAVCGDVFASPSAKQIFMAIKSVAGKMGCILIVKNYMGDNGSFSIAREMCKSQLPDIRVEIITVDDDISSILMKLNEFSNDNNDNIQDIRDKYKSITNRRGIAGTVLVHKILGGLAEQGKSIDEILKFYNKYISPSKSLNLVTMGVGLSSCIIPSVGSPSFTLNEKEMEIGLGIHGEFGIEKVELKPSKQIIKSLIDNLLKILPYSNNNNNNNNNNNNNNNNNNNNNNNSCGISCGSDGEDKSLIVLINNLGSTTNMEMAIATNDCLNYLHEKGFTVERLITGTLMTSLEMAGISISLLLIKNNQIINLIDLKTNAMGWPNSVLKPYKNKEDSILTLDENDSHEIKYDNLKSITISKENGEILKEIVLLGCNSLIENSNKLTDLDKQVGDGDLGTTLENLSKSIKKSIDTIPFDKPCYTFRKISLIIQELIGGSSGLFYSIFFLRLSNSLYERSTVNGKNQISTNDWGLSLIDAVNAIKELGKADIGDCTMLDSLIPAINKINQCCKDNENSSSSFDLLNTLKLASKEAQLGSESTIEMIAKKGRSSYLGERTSHIMDPGAHAIEIIFKSFLSIKK
The following text describes a protein:
Function:
Catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MEVVGLLCLAAAVLAWGFLWVWDSSERMKSQEQAGLLGGGSRSLLVIAHPDDEAMFFAPTVLGLARLRHRVSLLCFSAGNYYNQGEIRKKELLQSCDVLGIPPSSVRIIDNRDFPDDPGVQWDTQRVASVLLWHIEENGINLVVTFDAVGVSGHSNHVAVYAAVRTLHSEGRLPKGCSVLTLQSVNVLRKYISLLDLPFSLLRTRDVLFVLTSKEVAQAKRAMSCHRSQLLWFRRLYVLFSRYMRINSLQFL
The following text describes a protein:
Function:
Non-catalytic component of the mitochondrial inner membrane peptidase (IMP) complex. IMP catalyzes the removal of signal peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. SOM1 facilitates cleavage of a subset of IMP substrates.
Miscellaneous:
MISCELLANEOUS: Present with 358 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MAPPTTIRTRDQALAPLATLDSQTNCRLKELVQWECQFKGAEYVCSPFKRLFEHCIAPDKSATNYEVTDTYTNS
The following text describes a protein:
Function:
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression. As part of the SIN3B complex represses transcription and counteracts the histone acetyltransferase activity of EP300 through the recognition H3K27ac marks by PHF12 and the activity of the histone deacetylase HDAC2. SIN3B complex is recruited downstream of the constitutively active genes transcriptional start sites through interaction with histones and mitigates histone acetylation and RNA polymerase II progression within transcribed regions contributing to the regulation of transcription.
Subcellular Localization:
Nucleus.
Sequence:
VEDALSYLDQVKFRFGNQPQVYNDFLDIMKEFKSQSIDTPGVIQRVSNLFKGHPELIVGFNTFLPPGYRIEVQANEQVNVSMPGSLSTTITAGGITLATTTSVAGPSAPGAAPSPAGPNAAPPPAPAASSPPSGTKNRFQGQPDIYKQFLEILHTYQKEQRNLKETGGKPLTESEVYAQVAKLFQNQEDLLQEFGQFLPDANGASTHSLKPGSGLSKPSLVSGLGSSLKQGSTPLKRPLSHLSGSKQKMTSLKDVTLAEAGKHGTLNEFAFFDKVRRALRGQEVYENFLRCLILYNQEIVSRSELVHLVTPFLGKFPELFKWFKDFIGYKDLGGQVEPIPNKVRRSFSFLADYSSCKRYGASYRALPKNIVQPKCSGRTQLCKEVLNDTWVSFPSWSEDSTFVSSRKTQYEEYIYRCEDERFEVGLPTCFVLFLHPSFLRGFVFRIVRPPFFSFLHLDISESRLLALFSCFKRIALLNHIFYGIFLPHCMIEFGSIGAGAALVAVSWRFRTSFWHFEDAFAIWARVLTKVSGILNHSSLDPVTHSKTAIGLFIRRPTQRREQMEEGTGEVPVGPHMTLPYLDRSILDDAANLIIHHVKRQTGINKEDKQKIKQLLRQFIPDLFCLPRGELGGPDEGCEGNDKSRPRSSSEERNSVSEMSRDQPSLMQNLYSDDSYALFFVNDHWYLFFRLHHLLCERLTKIYRQSTNLAADEAKDRKDRKESTAGLRRSRSRTLAIFLTRCACSAEIEVEDYYLVFLDMVKSLLDGNMDSTQYEDTLREMFGIHAYTVFTLDKVVQNAVRQLQHIMCDEVCLRCTELFLEEHKVGAAGGPCSSASHRAHLEGSYQKKAEQALVNDTCFKLVLVSAFESTLMEKRSRNVRARRQQARKQEREAQMPAASAVGESHHSNNGTNNKSPCTNDESTNDEAPFTPAAVASPLGATVPAKTDVADDTQCRFNLSSYKMVFVVNSSSYIYNHRALRRARQSHRKVSERMHRNFGTWHRSWLDKNVSNEQDSQCEDWLQGLDYECITHCIKVQDCTRPPYCHFRRFRTAPAPPSPSNDDQS