lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm.
Domain:
The DNA-binding domain is intrinsically unstructured; The coiled coil mediates dimerization.
Sequence:
MTSPEGAQNKEIDCLSPEAQRLAEARLAAKRAARAEAREIRMKELERQQKEVEERPDKDFAEKGSRNMPSLSAATLASLGGTSSRRGSGDTSISMDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESQRQYEEKNKEFEREKHAHSILQFQFAEVKEALRQREEMLEKHGIILNSEIATNGETSDTVNDVGYQAPTKITKEELNALKAAGEGTLGKAKEVEVKKEIVEKVGQRETLQDSEQEQPKLNTGKDCVDRGVLHPGEKAENQRPVEDSALSPGPLAGAKCEQEVQSQDQENTSILKSPEQIESHEVTNKSDSRDSNSPEPSSCRGGLDSEVSGPTALGIKNQSENSMDSQGKENQEDLGKGSFEPRPDHVLGQTPEIDKVSCTDSRGTGGNHLEDVVQAGDTIVEDQVGTMASAEQSKSMENHIGRSLNDGLGQSSERELAHEAAELEEALTQSSQAGGENTVTEAEDAAVRDEKPLQADVQATPAAPTVQSGHQDTTGPGSTDTKHTSPHAKERNKAKSEQQAEALDSPQKKTKNKKKKNKKKKAAAPMETCKDANEESSCQDPDVGDGEEEERVQATDKKWAAETPELKEDPQSRPSGKQNDAEEDSGPAEGPTDVLDQNSLQCADGDISPVGRKGPQRDASQIGGEEGLVPSQHPGQADEKGIEGHSVDNSDLSGELGGFNSESGEQAREEVGNSKSKEDCTMS
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MKRRRDSNGKSIAALRAGVAALSVSSNIASRELTCRDSHVKAILDFLNDKVHPVMQVFGMPGTGKTASVNHALALLASSSPAGSKPTAVFLNGYIIQKTSDIYWTLNSHLSKTRLKHAENCLPEQCPALIEKRFKQGWGSSTTPLCVIVVDEVDKVLKKHNKAFFRIVDWLSLPYAFCKLITISNSMELAADAKTRSRLDITKRLVFEPYSLPELKEIILRRVSHIKPTLFAEKAINYLCNQTASHYGDVRRLLQSASSAICGLMMRIEEGYKLPEKHDGLLTVKDVHSVVRQIFHDRFVEFIQTIRLPVVFISVAVIAVETARLFRANCEDSRLPIDSLFTATKRAQERFGSVFADLHAVTLNYGAYLEIVEMLREVALIDVSVGEERIPVKTVQSLLEATERAHASMLQPFQTVVDACKLHDDFGTGICPLFSI
The following text describes a protein:
Function:
[Capsid scaffolding protein]: Acts as a scaffold protein by binding major capsid protein in the cytoplasm, inducing the nuclear localization of both proteins. Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid. Autocatalytic cleavage releases the assembly protein, and subsequently abolishes interaction with major capsid protein. Cleavages products are evicted from the capsid before or during DNA packaging; [Assemblin]: Protease that plays an essential role in virion assembly within the nucleus. Catalyzes the cleavage of the assembly protein after formation of the spherical procapsid. By that cleavage, the capsid matures and gains its icosahedral shape. The cleavage sites seem to include -Ala-Ser-, -Ala-Ala-, as well as Ala-Thr bonds. Assemblin and cleavages products are evicted from the capsid before or during DNA packaging; [Assembly protein]: Plays a major role in capsid assembly. Acts as a scaffold protein by binding major capsid protein. Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid. Cleaved by assemblin after capsid completion. The cleavages products are evicted from the capsid before or during DNA packaging.
Subcellular Localization:
[Capsid scaffolding protein]: Host cytoplasm; [Assemblin]: Host nucleus; [Assembly protein]: Host nucleus; [Isoform pAP]: Host nucleus.
Domain:
Region of interaction between pPR and pAP is called Amino conserved domain (ACD). The region of interaction with major capsid protein is called carboxyl conserved domain (CCD).
Sequence:
MVQAPSVYVCGFVERPDAPPKDACLHLDPLTVKSQLPLKKPLPLTVEHLPDAPVGSVFGLYQSRAGLFSAASITSGVFLSLLDSIYHDCDIAQSQRLPLPREPKLEALHAWLPSLSLASLHPDIPQTTADGGKLSFFDHVSICALGRRRGTTAVYGTDLAWVLKHFSDLEPSIAAQIENDANAAKRESGCPEDHPLPLTKLIAKAIDAGFLRNRVETLRQDRGVANIPAESYLKASDAPDLQKPDKALQSPPPASTDPDTMLSGNAGEGATACGGSAAAGQDLISVPRNTFMTLLQTNLDNKPPRQTPLPYAAPLPPFSHQAIATAPSYGPGAGAVAPAGGYFTSPGGYYAGPAGGDPGAFLAMDAHTYHPHPHPPPAYFGLPGLFGPPPPVPPYYGSHLRADYVPAPSRSNKRKRDPEEDEEGGGLFPGEDATLYRKDIAGLSKSVNELQHTLQALRRETLSYGHTGVGYCPQQGPCYTHPGPYGFQPHQSYEVPRYVPHPPPPPTSHQAAQAQPPPPGTQAPEAHCVAESTIPEAGAAGNSGPREDTNPQQPTTEGHHRGKKLVQASASGVAQSKEPTTPKAKSVSAHLKSIFCEELLNKRVA
The following text describes a protein:
Function:
Plays a role in synthesis, processing and/or stability of 23S rRNA.
Sequence:
MQKVKLPLTVDPIKDAQRRLDYVGYYAANQLERLAESVVNVLSDAQVTLSFYVDPQKLVVMKGKVQIDVDLECQRCNEPYKQTLECEFTYSPVANWDQADDLPEIYEPIEFNEFGEIDLIGTVEDELILALPLVPMHSSEHCEVSAQEQVFGVLPEELAKKPNPFAVLANLKQK
The following text describes a protein:
Function:
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
Sequence:
MTISSPSTKATLQLDQTLSPPLLTSSPAWQASFSIDGKYLAVCFGNPDTCIKVWEYLGKNSVDTVTTHNGVVGVGSDATSKGSKTVDCCTDINNTKSNTNHVEWKLIATIREGHSRTIRSVAFAPTSSTLGVPILASASFDGKVLIWEHFADEENHGTFEPIAQLEGHENEIKHLAWNQTGSLLASCGRDKTIWIWECFLPGTVGGSASGGGGDDEGEFECLAVLQGHEGDVKSIAFALSHGQWGEGDEILLSASYDNSIKVWAEESGDWYCAATLAVHTSTVWCLGINPGGVRFLSGSEDGSMAIWKMYTATERKRLFPREHAVSSTDGLWNSGHGRIASGGGDNCIQIYREETGGSGAGSSSDAPKFAIEAMVINAHDGDVNCVKWYPRVGTSLVSCGDDGAVRIWKYSLAG
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MPRKGMRSFFFSHKADSSSASHCPSPSRSTATPSIPRRSISDAAMAKGVEEAEAMIMKWDADTSAYAKVTSIFYESKKEAHDFIKCVNDLQKAMHFMVSENSSSEMVVRAQRLMQIAMKRLQKEFYQILSTNRAYLDPESVSTRSSRLSARSSTSDYDDDVGPEDEIRTAGDSISEVEQVSSNAMDDLRSIAECMISSGYGKECVRIYKIIRKSIVDEGIYRLGVEKLSSSQIHKMDWEIVELKIKNWLEGIKISITTLFTGERILCDHVFAASDSMRESCFAEISKEGATLLFEFPRLLVSKSKRSPDMAFRTLDVYTAISDNWPDIESIFSFESTSSVRLHALTTLSKLGESVRMMLSEFESVIQKDSSKSPVAGGGLHPLTQYVMNYLSHLADYSSILGDIIGDSPPPVQSPLPEFYFESSDTDNTPAPAISVRLAWIILFLLCKLDGKAKQYKEVSLSYLFLANNLQHVVSKVRTSNLRYLLGDEWISMHESKLRQFAANYERLGWGHVISSMPENPKAAISPEEAKETFRKFNLEFEQAYRKQSSYIVPDPKLRDEIKASIARKLDSVYQEFYETHRETLATIRNAEMLIRFAPEDVRNCLSDLFYGTGSGDSMSVSSTSSSSSPRRRHR
The following text describes a protein:
Function:
Required for the cytoplasmic assembly and the nuclear import of RNA polymerase II.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDANQKLLDFAKLLNQKNDSRPVIEKLKDNISGDLLNYFLNLLEEISKLDTDQPLSVTSLRCLQLFVHLTFLLGVYTQLPKEMLSQAKIKALPIYTPKKNLVQIYNILLPLLLTPSLLQGPLNLHYADLLLLHLYLLNCHEQGSLIEEPRPLFLDPSWKEKVTSIMSPQMVDPSKMISSCLSLLQPNVDNWLQDKLKHYLTTCLCRETGVQGFLKVYMQAQPNSIERARQAAHLISSVPKDISPQKYFSCILPQVWSLFSTQPRLASQLIIAVTNTHCDIVTSFLLKKLQILEAPKVIDLSPFENALDVLQVLVYIQNDDIIRICESCVPSLLHLQENTTLRSKVQDILLRIISVCGTKSLLRNLTNAKHLRIFCERLTKSQLAMFLPNLLEIWVQQPPDKRLELLELVQYALSNVDSDEIPSNVMLSVCTNLINEVASQNKYSSTEISQITTNREVEEENEEILLVLLNIISSVIGRNAELDLENPISSLLPALEQLSNYSNREISDLAKDVYKTLIQSKDDYSLALSYTQSDLVPVRGQGVYMLRKLIEKKDDRINPVRVLHVLINLLRDENSYVHLNVISAVVSLCDKYDDSLIRLLKEYTNTNKFTVDETLLIGQAIYQTMERQGELVAKFYGQIEQTCLSMLNNENTDIKISSLNIARLLCQMTSSDAFIESAKNILILEMGSDKQFLRRAAVQLLDSCKHLPDSVITTLSYVGSHDKDDFIKESCLNILANQADAAKYYLQ
The following text describes a protein:
Function:
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
Sequence:
MRVALLQLNSTVGDLVGNAGRIERAAREAAAAGADLAITHELALPGYPPRDLLLDRAFVADVQQTAQRLAHALAGVVPVLVGTAVPSAVGRPLANAALLLEGGECRETVLKGLLPTYDIFDEDRYFEAGQRAYPIEIAGVAMGVHVCEDIWNDREFWPRPRYRRDPVEELAGQGARYLLNLSSSPFYAGKQQLRERLLAHAARRHRLPVLYVNQVGGNDELLFDGRSCVFDGEGRLTARARAFAEDMLLVDLDSLAGRIEPQPTGEAEIWEALVMGTADYARKCGFQQGLVALSGGIDSALTLAIVAAALGPVNVLAVMMPSPYSSAGSIDDSLALAANLGVETLKLPIAPAMAAFDQILAPAFADLAADVTEENLQARIRGTLMMALSNKWNRLVFITGNKSETAVGFNTLYGCTAGALAVIADLYKGEVYRLAHWLNRDGAVIPEGILTKAPSAELRPDQRDSDILPPYDVLDGILRAHLEGGRTPEEIAGEGYHPEVIKKVLAMVRRAEFKRKQLPPGLRVSPRAFGIGWRMPIAHA
The following text describes a protein:
Function:
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Sequence:
MAYASIASLIRTMELLLTSDSPMLSLTFDLREEIIELHKKVSSIEAFLKNSEKQIHNHMAMTELEARIKGFANVAEDKIEFGLREAMITEDEMQRGKAHEELRESLQRVAKDIDCVQKESKKIQHHKGNQASTLSLLRDTSSSEMLPNLDVSNNMVGRDKEKERMLEELRGGSKDELKVIPIVGMGGIGKTTLAKQVFNHPSIQSRFDVRAWATICKEYNVKEILLSLLQSIINIDDKVYSRDEAELADLLQKKLKCRRYLIVIDDIWCYKAWDDTRQCFPIDNNGSRILLTTRHTEVAIYASSSNLHLKMNLMNADESWNLLKSKAFANESFTPELETIGEKIASKCQGLPLTIVVVAGLLSKSKRTKEEWENVAENIKSFVTKDPNEQCLRVLGLSYNYLPNELKACLLYFGIFPEDSEISVKRLVRLWIAEGFLKLEGDFEEEAKNRLQDLVDRCLVLVSQRSADGRNVKTCRIHDLVHELCLREAQSQNFLFIRNDKTEYVPQVGYRWISIQERQQTGVVQNEHGYRSLAHKHCFWLIRTPTDDDNSPLRRIRSIFLFAAPSLINNSNLELGHLNLIRVLDLNSMNFSSFPLQILGLFLLRYLSFSTRNSFGIPRGLRKLLNLQTFIVRGPVSSFIKFPELIWETTELRHLKLRNFYLPDPPSSSIDGERNLFWSNIQSVSGLIPYCCTKNILSRFQNIKKLCIRGHVYDYRVHEEDMDLRHLVDLHHLETLSIKVDRYQVSHWSSRFHKLPVYVPSAIHFPTKLKKLKLVGTRLSWEELNIVGQWPNLEVLKLKPNACRGLKWHPIEGGFPRLKFLLIEGTNLTRWKATNDHFPALEHLVIKHCFHLVKIPIEFADIYSLQLIELQNCKAKLMASTVRIQEEQEYLGSKPVDVRSYNDLAECELNGSDSDSD
The following text describes a protein:
Function:
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MLPETCLSPLEVTAMLSSPNPYHYPSQLEGLTRIERLFVFRDHPECIEVCCEVQPNRSYSVKDDSGNKVFSVTEADDCCGSQYAERFFVMNVTDNLNREVIRLVHPSVCTRCSSHELEVQSPPGTPIGYVRQNWHILLPKFTVENERGEPEFKIMGPSVFWTCCTDVNFELVPLNAAAVERSFGRIINPSYWAGPNPGANFVLEFPSSLQVKMKATVLGACILIHNMYYENKQ
The following text describes a protein:
Function:
Mn(2+)/H(+) exchanger, which transport Mn(2+)from the chloroplast stroma into the acidic thylakoid lumen. Might be a chloroplast-localized Ca(2+)/H(+) antiporter. Regulates Ca(2+), Mn(2+) and pH homeostasis. Required for chloroplast development.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein. Thylakoid.
Sequence:
MLSLNLSESLRIPFQNPRPPKSDFSSTSSSPSSSSRRCVSAYPIPIGFSVRNQYFSRCLTQLRRNESQQLGFRCFQRNDAACYLEKAESEEHDRNLDVLVESSIAHSRREIQRVLMFLAVSGSVALLGTDPAFAASSIPNVTQSLVTSFGDLGDISSGFASAFLLIFFSELGDKTFFIAALLAARNSAATVFVGTFGALGIMTIISVVLGRTFHYVDEVLPFRFGGTDLPIDDIAAVCLLVYFGVSTLLDAVSDEGKADEEQKEAELAVSELSGNGAGIVAAANTIISTFALVFVAEWGDKSFFSTIALAAASSPLGVIAGALAGHGAATLLAVLGGSLLGNFLSEKAIAYVGGVLFLVFAAVTVAEIVT
The following text describes a protein:
Function:
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
Subcellular Localization:
Cell membrane. Membrane; Single-pass type I membrane protein.
Sequence:
MSARTHRGPPENWAPPFACLCCVSAVLGMLWSPVSLAFNLDVDKLTVYSGPEGSYFGYSLDFYIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAERSAQCKQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATVRAHKGKVVACAPLYHWRTLKPNPAKDPVGTCYVAIQNFSAYAEHSPCRNSNVDPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITVSVADIIANYSFKDILRKLAAEKQTDVAPASYDDSYLGYSVAAGEFTGDSLQELVAGIPRGAQNFGYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNNDGMDDILVGAPLFMEREFESNPREVGQVYLYLQVSALLFQDPQVLTGTETFGRFGSSVAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNARGLHSKPSQVLQGIWGSQTIPSGFGFSLRGDADIDKNDYPATWWGHSKFIQTENSEEEFQTYGGDLLVGAFGEGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQIPEFPTPVACFSLRVCASIAGQSISNTVALMAEVQLDFLKQKGAIKRTLFLHNHQSHLIFPFVMRQQKSLHCQDFMVYLRDETEFRDKLSPINVSLNYSLDDSTFEDGLEVKPILNHYRENVVTEQAHILVDCGEDNLCVPDLRLSARPDKQEIIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGLRLLSCEYKMENVTRMVVCDLGNPMVTGTNFSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSVQINVTAVAQVEIRGVSHPPQIVLPIHNWEPAEEPHKEEEVGPLVEHIYELHNIGPSTISDSILEVGWPFSAREEFLLYVFHLQTLGPLQCQTNPEINPQDIKPAASPEDTPELSAFLRNATIPHLVRKRDVPVVQPHRQSPAKILNCTNIDCLQISCAVGRLGGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKIPYKEQPAKLPAGSTAIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQDEMTDREQLTSDKTPEA
The following text describes a protein:
Function:
Not known; lacks the phosphorylation site found in other PtsN proteins.
Sequence:
MKITELLSPENIRQGVSFSSKKRLFESIAHFVEEQILAEKGEQACFECLFEREKLGNSGLGNGIAMPKAKIPVTVSDKAIAVFMQLDNPIDYDAFDGKPVDLIFALLIPENQCETYIPVLASLIEKLTDKNVLKQLRSAKSADEIWQVFEITDQSETTFEEVKE
The following text describes a protein:
Function:
This enzyme has both lysozyme (acetylmuramidase) and diacetylmuramidase activities.
Subcellular Localization:
Secreted.
Sequence:
MRLHTLTWLLSLSLASIVTATAPVLRNATVTRGIDLFEIHLPVNWKTAVAEGVEFVFVKSTEGIAYRNLRFKSQTGSAAAASTSSNTTILHGAVHFALASQSTGAAQADFFISHGGNWTADGATLPGVLEMEGNIPGKLCHGMSATEISDWMMDFSDRYKEVTGRRPILFLSAGWWEKCAGNNETFAQEHPLWLANWADEMGDLPAGWKEATFWQYSGSAGDGSCKVNLPESASSSLAFPILAEN
The following text describes a protein:
Function:
Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
Sequence:
MALHKGLIMLKRVFTPNKCCTRLFGNGTNTLYQSGPPHAKFFPVCDGVMLLPGTFKNKVAFITGGGTGLGKAMTTTLSSLGAECVIASRSLDVLQKTADEISQQTGNKVHAIRCNVRDPASVEAAVDQLVKDVGLPDVVINNAAGNFISPSEKLSPNAWKTITEIVLNGNAYVTLDIGKRLIKAEKGAAFLSITTIYAESGSGFVVPSAAAKSGVEKLCTSLAAEWSRYGMRFNVIQPGPIKTKGAFSRLDPAGVFEKKILDRVAVGRLGTPGEIANLAAYLCSDYASWVSGAIIRMDGGEYVSMAGEFNDLKQVTKEQWDMMEAMIRNTKGS
The following text describes a protein:
Function:
May play a role in Cajal bodies formation.
Miscellaneous:
MISCELLANEOUS: Overexpression changes the morphology of Cajal bodies, while depletion disrupts the localization of components of Cajal bodies, reduces splicing capacity and inhibits cell proliferation.
Subcellular Localization:
Nucleus, Cajal body.
Sequence:
MASTGSQASDIDEIFGFFNDGEPPTKKPRKLLPSLKTKKPRELVLVIGTGISAAVAPQVPALKSWKGLIQALLDAAIDFDLLEDEESKKFQKCLHEDKNLVHVAHDLIQKLSPRTSNVRSTFFKDCLYEVFDDLESKMEDSGKQLLQSVLHLMENGALVLTTNFDNLLELYAADQGKQLESLDLTDEKKVLEWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYENKSFLFLGCGWTVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKVISYGDDYADLPEYFKRLTCEISTRGTSAGMVREGQLNGSSAAHSEIRGCST
The following text describes a protein:
Function:
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
Miscellaneous:
MISCELLANEOUS: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
Subcellular Localization:
Cytoplasm.
Sequence:
MKNEKINILNLTQEELTELLVSLGLKKFYGKEVFIWLHKKITRSFDEMTNLSLKDREILKEKTYIPFFNLLKYQVSKIDKTEKFLFELEDGGTIETVLLRHKDSKNKEIRNTLCVSSQVGCPVKCSFCATGQSGYMRNLSVSEILNQIYTVERRLRKKGENLNNLVFMGMGEPLLNIDNLSKALSIISNENGINISKRKITISTSGVVSGIEKILLDKIPIELAISLHSAINEKRDKIIPINKNFPLEDLSAVLIEYQKQTKRRITFEYILIDNFNISETDANALADFIHQFDHVVNLIPYNEVEGAEHTRPSVKKINKFYIYLKNVRKVNVTLRQEKGSDIDGACGQLRQRNKKGDN
The following text describes a protein:
Function:
Serine/threonine-protein kinase with low activity.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MHIPFKPLLFILFFFFFHGTNSFGTMGPISASFGEYELFCSIDASGKQDVICWGKNTTSPQTPSSSSYVNNIPAMSALSGGEGFLCGILANTSQVFCWAATSKQNADPILVPPAYRTTAYSHVAAGQNHVCAVRGSYYSDRDSGTVDCWEIAKRSKNGTLMAVINESFDDQSVTNLEMNRVVSGEGFTCGEVRDGGLVCWGPNSENLKVSNVSDSFAVLAAGRTAVCGVLNASGDLRCWGDIEPPLKTEVRFVSLSGGARHFCGVREDNHVIECWGNLNSSLVPKGYGFMAIASSDYTTCGIREADLLLDCWLVNASKPDFDPPLELSSPGLCRSSSCEANEFDFNVSVLNQPDLTSLCVRQDLRICSPCGYNCSQGFFLSSPCTQNSDRVCTACSLCQNSSCLNVCKLHSSNGFWHWHHIRRWVLIIGSSVLCLLLILTCGCILRCSTGSRRKHGTKKQSKSCIGKHEQENDDEVNGNGNGLLHSASSAASCPGLPQVFRLSELKDATNGFKEFNELGRGSYGFVYKAALADGRIVAVKRANAATIIHTNNRDFEMELEILCKIRHVNIVNLLGYCAEMGERLLVYEYMSHGTLSDHIHGGLSPLNWSLRLKIAMQTAKGIEYLHKELLPPIVHKDLKSSNILLDSEWGARVSDFGLLTSSDKDLISDLESDVYSFGIVLLEILSGRKAYDRDFDPPNVVEWAVPLIKQGKAAAVIDRNVALPRNVEPLLKLGDIAELAVRENPSERPSMSDIASWLEQIVKDGLIL
The following text describes a protein:
Function:
Sodium transporter protein, which plays a central role in plant tolerance to salt. Upon prolongated exposure to high concentrations, Na(+) translocates from the roots to the transpiring leaves where it can increase to toxic level. Involved in Na(+) recirculation from shoots to roots, probably by mediating Na(+) loading into the phloem sap in shoots and unloading in roots, thereby removing large amounts of Na(+) from the shoot. Does not transport K(+) but regulates K(+) nutrient status via its ability to facilitate Na(+) homeostasis. Probably not involved in root uptake of Na(+).
Miscellaneous:
MISCELLANEOUS: In contrast to K(+) channel proteins, it lacks a conserved Gly at position 68, explaining why it does not act as a K(+) transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDRVVAKIAKIRSQLTKLRSLFFLYFIYFLFFSFLGFLALKITKPRTTSRPHDFDLFFTSVSAITVSSMSTVDMEVFSNTQLIFLTILMFLGGEIFTSFLNLYVSYFTKFVFPHNKIRHILGSYNSDSSIEDRCDVETVTDYREGLIKIDERASKCLYSVVLSYHLVTNLVGSVLLLVYVNFVKTARDVLSSKEISPLTFSVFTTVSTFANCGFVPTNENMIIFRKNSGLIWLLIPQVLMGNTLFPCFLVLLIWGLYKITKRDEYGYILKNHNKMGYSHLLSVRLCVLLGVTVLGFLIIQLLFFCAFEWTSESLEGMSSYEKLVGSLFQVVNSRHTGETIVDLSTLSPAILVLFILMMYLPPYTLFMPLTEQKTIEKEGGDDDSENGKKVKKSGLIVSQLSFLTICIFLISITERQNLQRDPINFNVLNITLEVISAYGNVGFTTGYSCERRVDISDGGCKDASYGFAGRWSPMGKFVLIIVMFYGRFKQFTAKSGRAWILYPSSS
The following text describes a protein:
Function:
Required for vacuole segregation and vacuole protein sorting. Possibly part of a complex which tethers the vacuole membrane to microtubules, either directly or via kinesin or dynein-like motor proteins. Probably functions in several interorganelle traffic pathways (By similarity).
Sequence:
MQNGKRRIGVRISSNLSNHSGTNLSTSAQSDSSNIVKATECPICGLELPNLSALNDHLDVTHFNDNEKIHKRQDSINSWLTRTLNGASALQMKAAQRLWRMEPYEQNGDSSGAVGLEATKLTDSLVVKNHWQPEVPDMVCHDPMCDKLLNFINGHIHCRKCGYIFCNFHSMYQIKLSIHATYDSENGFWCRVCRECYEGRPGYNDSNGLIRSRFQTFETFRKPLADKRRIEFLRLSKRMKKLEELWTSENVSMLDALLLNKAKRLEQSIVHWQDDSVVQICPECNNSFTLTRRRRHCRLCGRVICRFCVLEISLPQHPQPLLICMSCNQNYFRNVLYQTERSKSLGYIRHIEHLQVFRQAMVNYYRLYEDSLSELLSGEIITEATLKIVKDRRKKFLELCVKYDGTMKKIANHPSSNDAEEQFKQNVVNEAKRYLQETILRLQAIPYHLQVGQAWTSESERELEKKKEQVEKKQEELMQTRIVLEEQVFLVENMIEDAKAKRKFSEVETLLSSLAPLHEEIHSITEKIHDLDLFDI
The following text describes a protein:
Function:
Required for intestinal cell division following the 16E cell stage of embryogenesis. Regulates intestinal cell divisions and binucleations probably by modulating the activity of the cell cycle regulator wee-1.3 and by activating the cdk-1/cyb-1 complex. Plays a role in male tail development, via regulation of the cell divisions of the ray precursor cell lineages, perhaps acting together with cell cycle regulators cyl-1, cdk-1, cyb-3, and cyd-1.
Sequence:
MNRPSQISQDVAQPLSNQHETAMMSSDEDSMSRDSGICELMDENTPVCFSSMSTESTTVQVEECMEIDEDENLQPGPVSRRQKKVTFRREKSSCQVRLFDESPTSHKMFMRPQAPLSVRSENQQLLQQRKRKFEKSEQSSDHFHLEPMSVEAMDDDEIVMMDQNTTKWEPGFRAPNHKKGRLTRSATAFPSLETFEEEEHEEQHHLNVKYHLKTVAKESSKGFRRITAETLRDIFFRLSEKEFDDKYILIDCRYPYEYNRGHIKNAINHFDRVTVSKIFYDENGRKRCNKIPIFYCEFSQARGPKMAYALRQVDRELNVNHYPKCDYEEMYVLDLGYRNFFFAANEANITNLCQPHAYCEMHDKEHTMELKKYNFHNKGQSVLRTVSMSRSFKSLPTGSAFNFVASSASFTSAPSTSTENIDTNDDCQKSRTPAVPRIASRRNLFSDPSHSPTNFAQFPLTCSRETPSPHKHPLTCPRFS
The following text describes a protein:
Function:
Central component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore.
Miscellaneous:
MISCELLANEOUS: Present with 5680 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein.
Sequence:
MSQSNPILRGLAITTAIAALSATGYAIYFDYQRRNSPQFRKVLRQRAKEQAKMEEQAKTHAKEVKLQKVTEFLSMELAKDPIPSDPSEREATFTTNVENGERLSMQQGKELEAASKFYKALTVYPQPADLLGIYQRSIPEAIYEYIILMIAILPPANVASFVKGVVGSKAESDAVAEANDIDD
The following text describes a protein:
Function:
Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression.
Miscellaneous:
MISCELLANEOUS: Present with 704 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MSRTIPFLFKLVNRAVILPTAGFTLGVGAFVKAWPDDAGVLSLNDPQTPAELISATKSRQPMELQRVDILAQIEKSEVYNKLAQDEKMHHVLFSEKIPSGHREYHVGQGLLFGKGKLEIDPLVFHDVNHGELTVIYHLGAELGNRDGNVHKGLLSLLLDEALCYCGFPLLPSKRGVTARLSLEFFEDIPVDTTIILKANVKEIKGRKCIIEGHLEQFPLEVSSRNGTRSWNLPHIWGFNHKQEMAKKFAKANCILVEPTWFKYFKWLDMF
The following text describes a protein:
Function:
Produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MATFHFDLVSPEKLAFSGEVDQVDIPGVEGDFGVLAGHAPVVAAIRPGILTVTTAGRHEKIIVLGGLAEVSEKGLTVLADVATSLDELDRAQFAETIAEMEEGLKEHEGGELDLAIERLDHYKSIQQQLSSTAMH
The following text describes a protein:
Function:
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
Sequence:
MKVLNLGSKKQASFYVACELYKEMAFNQHCKLGLATGGTMTDLYEQLVKLLNKNQLNVDNVSTFNLDEYVGLTASHPQSYHYYMDDMLFKQYPYFNRKNIHIPNGDADDMNAEASKYNDVLEQQGQRDIQILGIGENGHIGFNEPGTPFDSVTHIVDLTESTIKANSRYFKNEDDVPKQAISMGLANILQAKRIILLAFGEKKRAAITHLLNQEISVDVPATLLHKHPNVEIYLDDEACPKNVAKIHVDEMD
The following text describes a protein:
Function:
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MDIQLFQGYGGKVIVAVDYGERKCGVAFGEILPQKSLVIPTKNLKEFIRKLKPDKIIFGLPLSMSGKYTQQTFKTVAVAFKFSKEYETYLCDERLTTKIGERISKRDDAVSAALIFQSFFENSSVCEKVTDPRKKVDLALEKVDGEVLLYEFPDPSLNIEAREVDVVTKNPVLAYFYSKNGYFVGRELWEKKYDLIISGKNCEELKKYLKENGRLVCL
The following text describes a protein:
Function:
Responds to activation by environmental stress by phosphorylating downstream targets.
Sequence:
MASAAVALPSSATGGSLNPTAPASTSVNATTTTSITNAPANKPKQAGSRAVGEPRRVRFNVGSKYHVMDVIGEGAYGVVCSAIHRPTGQKVAIKKIVPFDHSMFCLRTLRELKLLKYFQEHNVSENIISIVDIIRPPTIEAFKEVYLIQELMETDMHRVIRTQVLSDDHCQYFIYQTLRALKALHSADVIHRDLKPSNLLLNANCDLKVCDFGLARSIRTAEQETGFMTEYVATRWYRAPEIMLTFKQYTKAIDVWSVGCILGEMLSGRPLFPGRDYHHQLTLILDVLGTPTLDEFYAINSRRSRDYIRALPLRKKRPFATLYPNASALAIDFLNKTLTFDPKKRLTVEEALQHPYLEAYHDPEDEPTAPPLDEDFFAFDRQKDEISKEELKRLLFEEINSFNSSTGTTTQS
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis.
Subcellular Localization:
Cytoplasm. Membrane; Single-pass membrane protein.
Sequence:
MGEEQSTVSGGGGPQESQTLAGGTAGHPEPPRPQGDSARAPPLRAASAEPSGGGCGSDWGCADTSAPEPARSLGAPGWRKSRAPAQPAGLALTGPLNPQTLQLQLELEEEEEEAGDRKEGGDEQQEAPPGEELEPRTRAGAADGLVLDVLGQRRPPLAKRQVFCSVYCVESDLPEAPASEQLSPPASPPGAPPVLNPPSTRSSFPSPRLSLPTDSLSPDGGSIELEFYLAPEPFSMPSLLGAPPYSGLGGVGDPYAPLMVLMCRVCLEDKPIKPLPCCKKAVCEECLKVYLSAQVQLGQVEIKCPITECFEFLEETTVVYNLTHEDSIKYKYFLELGRIDSSTKPCPQCKHFTTFKKKGHIPTPSRSESKYKIQCPTCQFVWCFKCHSPWHEGVNCKEYKKGDKLLRHWASEIEHGQRNAQKCPKCKIHIQRTEGCDHMTCSQCNTNFCYRCGERYRQLRFFGDHTSNLSIFGCKYRYLPERPHLRRLVRGSVCAGKLFIAPLIMVLGLALGAIAVVIGKKHFMYLRLELSEGHRENMSVNVII
The following text describes a protein:
Function:
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular Localization:
Nucleus.
Sequence:
LVSSFVNRARQLQLRQNYRKLIDETQLNKEELVKPDSNGLMENIAKAHQLFKDVNETRGAALDSKFMTLAVTLGAQKTNLLQTDLVAFQPDEFIAKLVTCMGGTVSEDKDEIDIPENGWNVLGQKTATYFTSLTPALHPLLGAFEAIETGKTNRQATQRNKQKETSTKVQLPKELTNYKDDKKEATPEEIERVLHIINTFYKDDPASPIDYFELVVNPESYGHTIENIFHLAFLVKDGLVKIFLNENGLPVVEPVNVRPDDISPRKKVQVIVSLSMDEWYAIIDAYQLKDSLIKILF