lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. PccX could be responsible for the interaction of the biotin carboxylase and carboxyltransferase subunits.
Sequence:
MTEDLLSGLSIPDDADSEEAAAIAAAVGAHLHDQTAAAVAAAADEEETWDEKRWQYAGRLDSVTGCARRVPSGAPTNAWAASGRTDRF
The following text describes a protein:
Function:
Exerts both phospholipase and triglyceride lipase activities. More active as a phospholipase than a triglyceride lipase. Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins.
Subcellular Localization:
Secreted.
Sequence:
MRNTVLQLCLWSAYCGFATGDPTPLGPEGRLQGEFDKSRVVPTAAKPPVRFNLRTSEDPEDEGCDLSLGHSQPLEDCGFNVTAKTFFIIHGWTMSGMFENWLYKLVSALQTREKGANVVVVDWLPLAHQLYVDAVNNTRGVGHSIAQMLDWLQGKEDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPLFEGADVHRRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIAYGTIAEVLKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKTRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFSYKNMGEMEPTFYVTLYGTNADSQVLSLEMVEQIGLNATNTFLVYTEEDLGDLLKIKLTWEGKSQSWYNLWKELRSYLTQSRGSKQELHIRRIRVKSGETQRRLTFCAEDLENTLISPGQELWFHKCLDGWRMKNQTSPTVEHL
The following text describes a protein:
Function:
Dioxygenase that cleaves the interphenyl C-alpha-C-beta double bond of resveratrol to yield 3,5-dihydroxybenzaldehyde and 4-hydroxybenzaldehyde. Also cleaves piceatannol, a compound that differs from resveratrol only in the occurrence of an additional hydroxyl group, which leads to the production of 3,4-dihydroxybenzaldehyde and 3,5-hydroxybenzaldehyde. Exhibits a high degree of substrate specificity, as suggested by the lack of activity on carotenoids and the other resveratrol- related compounds.
Sequence:
MAPTATQDPVAVAVPASKAAKHGYVHPTDMLPSGWPTATDLSGGAQPRRFEGTIFDVMVRGTIPKELYGTFYRIMPDYAEAPTYYKGGELNAPIDGDGTVAAFRFKDGKVDYRQRFVETDRFKVERRARKSMYGLYRNPYTHHPCVRQTVDSTANTNVVMHAGRFLAMKENGNAYELDPHTLQTLGYNPFKLPSKTMTAHPKQCSVTGNLVGFGYEAKGLATKDVYYFEVDPSGKVVHELWLEAPWCAFIHDCALTPNYLVLMLWPFEANLDRMKAGGHHWAYDYDKPITWITIPRGAKSKDQVKCWYWKNGMPIHTASGFEDDQGRIIIDSSLVHGNAFPFFPPDSAEQRQKQQSDGTPKAQFVRWTIDPRNDSNERLPDPEVILDTPSEFPQIDNRFMGVEYSSAFINVFVPDRSDGNKNVFQGLNGLAHYRRKQGTTEWYYAGDNCLIQEPVFSPRSADAPEGDGFVLAIVDRLDLNRSEVVIIDTRDFTTAIAAVQLPFAIRSGIHGQWIPGQVTPDFDSRGLIDLPKQQHWAPPSQSAFDPNM
The following text describes a protein:
Function:
Involved in cell lysis.
Subcellular Localization:
Virion membrane; Single-pass membrane protein.
Sequence:
MDNILDPLKAPFSSEAAAKTTAAKIAVVYALVGLVGGLLLTK
The following text describes a protein:
Function:
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MTSLAVLVDGSACAWGAFAEAKREKPGMEKEVLTRAFRSIVTFSNVHLSLAQSNQLLLYAYGNGMSKKLLYDSVRSDNPDSSSCIIKGIRGALRENSTSGDARKCGVLAATLATAICQIRKAATLGTNKSEETISGQKGRIVIISLLPDFGSQHSLLMNLFFSAHKHDICIDVVSLGGSSALLQQAADITAGVFQVIHKIEDLPRILMTRCLPVSIRDSTSFTTVDYRAACVCHEKLVSNGWTCSVCLAVLCSFMAICPSCGAVFKITVPRRKRKRPTEVGAAPSPRP
The following text describes a protein:
Function:
Plays a role in regulating calcium and manganese homeostasis responsible for cell cycle progression.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MDSIELKQLVPENDSEPGTPRQLLFQHYDISNEETIGIKPFKSIPAKVYILRVTEILTLGLLHLILTWLPEFRLKWIEAPCSNEDVEFVAISDPSGTSSIEKVSSICLKNDIQTSSFVLPSGKTRYFEYKKLRFYLEPLNLQWVLMPLETSAYSLVTSTPAYIQNGLDTFTIAKLRQVYGSNSLVSTKKSIVTILLNEVLHPFYLFQAVSVLIWLCDSFVFYSCCIVFISSYSIFLSVKESKESENRIHSIIGAPQPVTVIRNQVKQTVLADDLVIGDLLYFSNLDLKTCPVDGILFSSSCLLDESMVTGESVPARKFPLEDNSLDSWMIASCNIFSPHLIHAGTKFLKIDSTPSTPCLISVVRTGFRSNKGQLIRNLLYPNLRPSQLYLDSMSFLKTMAILSFVSIVFIAIYLNLYNASFGHVVLRSLDVLTILVPPALPATLSVGIANSIARLSRALIYTTSPESIHNAGCLSTFVFDKTGTLTENSVQLSCVYVKSGSNGLLKQVDADSLSLDSTKLNAHAYRVATCSQSLELVGNELVGDPLEVTLFTQFNGTFCATIRASNTPHPPLFSVSNSFDGPSQIFSIYKALEFDPVLRRMSVICSTSTERSLMLFTKGAPESILAISSQQSIPSNVQEVIHTLSSKGFRIIAFASKNLITPLQELIHLSRSTLESNVTFQGLFVLESPLRESSKDVISSLLRSKMEVSICSGDSLFTSVFVAKHCGALDSCNFIYTAELADSGDDCPQIHFEKIDLQTQNFQPIPDGFSLKDVILEKDSSLCMDGKLLQRLLTMLSFNEIKILLSKLRVLARMSPFDKATYVELCQKYGCKVGFCGDGANDCIALKQADVGVSLSDSEACAAASFVSKKKSIKDVFNVLLEGRCSLILSHRCFQYMVLCAIVQFSGVFFLYLKNYNFNDNQFLFMDLLIIFPLSAAMSYFDPAQNLTSNRPNSTLFGKGRVKDLGIQSVLIWLSHGLLTLILHELNWVELPEWQLEKSNTKNVLVTSIFLLSSLQYLGICIGINQSSEFLSPIWKKKTYVCLCTTIGLCNIYLCFANENHIISRCLQITRLPTLYRFIILFMGVISCCLTSILNM
The following text describes a protein:
Function:
Is required for retinal production and bacteriorhodopsin biogenesis. Probably catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSNRSQFVPSWLVPEAAGDLPLTVSRLSLLALAAAFAVGYGAGFAVPLEVQAGVYLLGMVAMNLPHGGYEHFENLRRRAASFQGKYIVAYLVGIAAFGALFFVAPVAGLGLAVTVAVAKGGFGGVQSMDALYGTDHLRTRPQRWLAAVVRGGAVMVVPMLFWTDVFYAFSSVMISIFDPSAVSALGGDIATRRLVLGGGYGALVVAHLGLGYRRAAGTGSFLADAAETLLLIAYFALVPVVIAVGLYFPLWYSARQVARSSAVDDTAMTQADATGMLDALDADDPARATLASWAVLIVGSVATFGLAAVLWLLSPQPLGGGGILVGLVAFWSIFVSIIALPHVVVGGWLDRTRGIWYVP
The following text describes a protein:
Function:
Involved in development during embryogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MHTSTDPMHTLHDSVSLSPPLIKSSRGGSSIGNGIGCSASSRTAAADAMSMGCDDSDIEPSSMGGSGAAGGNGDGSGSSGGPLVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSPFWIRKPVPLVPVHFNVPNFNGSREFDVVHNPADVFDSALRADKKFNFFANAEASFYQGSQSGDKFDRLPFMNRGRGADVLDALPHSSGSGGGVGGGSESSRGSKYKSPYAFDVATVASAAGIPGHRDYAERLSAGGGYMDLNVYNDDADTEADAEAEGDDDSCEDKIDVESGNEQEDSHISDSVDSACTNRLDAPPEALIFEASAEASDSSPRRRFDSEPLVLRTSKQSSAKDFRIETLIGHHLHRGGSQEETSD
The following text describes a protein:
Function:
Lyase that catalyzes the C1-decarboxylation of 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid into 2-methoxy-6-(all-trans-polyprenyl)phenol during ubiquinone biosynthesis.
Miscellaneous:
MISCELLANEOUS: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MQSRVVSSAVMFLGGIAGAVKSLPAFVTSSFGAIVDPEDGRGSAAFAEITALTALHHMQRLMMADEMGRSILKERPQVTDETLEFAKTQPEGTFGYRYAAFMKRNNFLPSGRAPILHVSDPTLAYVMLRYRQIHDFVHAYVGLGRTIEEELAVKLFEWQHTGLPVGLMAVLGGMPWLRMDQILNMGMYNEWARANAPRQLHGKRFVSCILNVPWEWYLDKPYEQLVDDVGIVPLDAFLKERKSGGLHDS
The following text describes a protein:
Function:
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.
Subcellular Localization:
Cytoplasm.
Sequence:
SQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGXTSNVLIIGELLKQADLYISEGLHPRII
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of 5-amino-6-(5-phospho-D-ribitylamino)uracil, also known as ARPP, but has no activity toward flavin mononucleotide (FMN).
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAEAIGAVSLVGHRPSIVRITVKNELKTQKSQSIVRFPVKVDYSAKGVLSHLMTQSVKKNRMSVFPIRALAMELTKEKKKDDRLPKTWNYLDSGADDKPSLWPPENKADKPSLHNPLLRQERMGCGWLGAIFEWEGVLIEDNPDLDNQSWLTLAQEEGKSPPPAFMLRRVEGMKNEQAISEVLCWSRDPVQVRRMAKRKEEIFKALHGGVYRLRDGSQEFVNVLMNNKIPMALVSTRPRETLENAVGSIGIRKFFSVIVASEDVYRGKPDPEMFIYAAQLLDFIPERCIVFGNSNQTIEAAHDGRMKCVAVASKHPIYELGAAELVVRRLDELSIIDLKKLADTDLTEFEPELEMEKEDERELPSSAVAVDDF
The following text describes a protein:
Function:
Functions as a regulatory ATPase and participates in secretion/protein trafficking process. Has ATP-dependent protein disaggregase activity and is required to maintain the solubility of key mitochondrial proteins. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and pro-inflammatory cytokine IL6. Plays a role in granulocyte differentiation.
Subcellular Localization:
Mitochondrion intermembrane space.
Sequence:
MLGSLVLRKTAPAPRLLLQLLRSPSLRSTTGRSVTTGGRGEPQWLRAAVGGRHGTSPALLAEGGAATGGRQRGSTETPCLAASTWGRLPSPEDPLPGQDSWNQVLNRAGLGVWALASALVAHCYSKSPTNKDAALVEAARANNVQEVRRLLSQGADVNARHKLGWTALMVAAISRHDSVVQVLLAAGADPNLGDDFSSVYKTAKEQGVHSLEVLVTREDDFNNRLNNRASFKGCTALHYAALADDYRTVKELLDGGANPLQRNEMGHTPLDYAREGEVMKLLRTSEAKYQEKQRKREAEERRRFPLEQRLKEHIIGQESAIAAVGAAIRRKENGWYDEEHPLVFLFLGSSGIGKTELAKQTARYMHKDAKKGFIRLDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMSRNRIAENLGDVQSGDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWAKRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPEGCCLRISVEDSDAQLLTGPELPPPGAEKRPPKLRLEIIDKDSKSHKLDIRAPLHPEKGHLESSWGLASLSESRQWGPFPWVMEGRHDKKTSLRDAKSASDPAVWNIPIE
The following text describes a protein:
Function:
Catalyzes the reduction of the glycolytic intermediate dihydroxyacetone phosphate (DHAP) to sn-glycerol 3-phosphate (G3P), the key precursor for phospholipid synthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MEPFKHPIAILGAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGVNNRYLPNYPFPETLKAYCDLKASLEGVTDILIVVPSFAFHEVITRMKPLIDAKTRIAWGTKGLAKGSRLLHEVVATELGQVPMAVISGPSLATEVAANLPTAVSLASNNSQFSKDLIERLHGQRFRVYKNDDMIGVELCGSVKNILAIATGISDGLKLGSNARAALITRGLTEMGRLVSVFGGKQETLTGLAGLGDLVLTCTDNQSRNRRFGLALGEGVDKKEAQQAIGQAIEGLYNTDQVHALAQKHAIEMPLTFQVHRILHEDLDPQQAVQELLERSPKAE
The following text describes a protein:
Function:
Catalyzes the two-electron oxidation of bromide by hydrogen peroxide and generates hypobromite as a reactive intermediate which mediates the formation of sulfilimine cross-links between methionine and hydroxylysine residues within an uncross-linked collagen IV NC1 hexamer (By similarity). Plays a role in the attachment of tissues and in axonal guidance during early developmental stages. May functionally antagonize the peroxidasin pxn-2 to maintain neuronal development.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix. Note=Localizes to the extracellular space in between body wall muscle cells.
Sequence:
MNLYLLLLVIATSSWQFVAGLECPVECTCDKKGLVVDCSSSGLTRIPKNISRNVRSLVIRNNRIHKLKRSDLEGFNQLETLVLTHNKIKIIEENVLDHLPELKRLSLAHNELVYIPPLCSDSRPLASLNLKRNHIQFIDEQVLRYFPDLTQLDFSHNRIQSLRTKLFDNLPALSHAHLHSNPWHCDCRASKVKALLQKVKWEKKVYCTNPVELRHQALDEVDDSALTCARPAEESWTGEEIKLTCAKNSSSKLVVWMYENVEVDSSSLDGYEIHDTVITVPRKTNVNFMTCTYDFDHIPHHRRLRQSQHQGNGSPQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYPFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANGNPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAGNPVGAMSADAKLTVIGGETRKAAAPQIDEELLRAIAQKARQNVENAVEKTRKQLTQDKVTNTNDLKRLFRFSTPKQAVELSKAREIYEESVRLVREHVEKGLILNVDELHPKNVSYESVLHVTHVQALMGLSGCHTGQYKNPCTDTCFHHRYRSFDGQCNNKNKPMTGVSLMPLRRLLKPVYENGFNTPVGWEKGRLYNGYPLPNVREVSRQLVATENITPHSKLSSMVMQWGQFVDHDLTHTVTALSRHSYATGAFCNRTCENLDPCFNIPLSPNDPRVKSGSAKYPCIEFERSAAVCGSGETSLVFNRVTYREQMNALTSFLDASNVYGSNEVQAQELRDTYNNNGMLRFDITSEAGKEYLPFEKDSNMDCRRNFSEENPIRCFLAGDLRANEQLALAATHTIFIREHNRIAKKLKSMNGNWDGEIIYHETRKIVGAMMQHITYKHWMPIIFGGQAQMNKFVGTYQGYDPDVDASVTNAFATAAFRFGHTIINPSLFRLGNDFMPIKEGHIALHKAFFTPELVLTQGGVDPLLRGLFASPLKHPMPTQLLNMELIEKLFMKGHEVSLDLAVMNIQRSRDHGLPSYTEYRKFCNLPVPVQWEDMKGYIKDDMIIQKLRGLYGVPQNIDLWVGGIVEEKLENGLFGPTFACIIGEQFRKIRDGDRFWYEKDGVFTPEQLREIKKITLARLFCDNGDNIDRIQKDVFMYPGMDKENYGTCQETEMMNLRAWSKCCDNVCPTMLDRILRSRHRGSRLHGCNQNGIWRPEGAKWIPQNEICTECVCQGSRVWCSTKEDCSDNRSPF
The following text describes a protein:
Function:
Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth. May act as a scaffold protein that recruits the calpain-like protease RIM13 via SNF7 to its substrate RIM101.
Miscellaneous:
MISCELLANEOUS: Present with 2881 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSELLAIPLKRTLEVDFATELSKLIDTTSFQTASFFQSDILKVVDARNNAIAPDISIDGLSALKEYYVILLQLEKKFPNNQIEFTWFQTLSQKSRGTSQYSLQWEKLTIIYNIGCMYSLLALNSNNDAAESLKTSCLYFQNAAGCFKHVLDHQKNLETIPVVDDATLNALTSLMLAQAQECFWFKAVQDKHKDSLIAKLSQQIVDFYCEAINDAQRGKLIRSDWINHLKAKKAYFSAVTYYRIALSFNEKKQFGNVVKALQMGLQFINESTLSSQAKFKTVVESSLKEAQRDNEFIYLQEVPSELPSIKPALMVKPSSSATLLPSIKKDETLFKDLIPIEVMEYCTAYNERQDEYVEQRVTNPLASLNKLLKESLTTFQIPQGLTKVSEAELSHYQASLNNLLINNKNVQVQLDNIEQILNEEAFTDNQLRLKHGTLNWTLPESSTTNTAYYEKLKKLRGYLDEGSAIDKQTNELFQSIDKNLIGSEIRLPESNDPLTNKIKMIIQERNDYIDRTRRKSSEYRILPKIITSYKKNGTVDFEPIFIGHLKYFDEDLRYVNSTKEENIKLIEEVNLSKKNNPGRSGIEPKKMVRIDPRELYIEDLRYSFKLLDEVKENLSAGTAFYENLITSTSNLYNEVQEYDTARRAEKARLDKSLTFEDQ
The following text describes a protein:
Function:
Adapter protein that connects P-granules in somatic cells with the autophagic machinery. Association with other adapters such as epg-2 and P-granule components such as pgl-3 is required for the accumulation and degradation of P-granules by autophagy in somatic cells. This ensures exclusive localization of the P-granules in germ cells.
Subcellular Localization:
Nucleus. Cytoplasm. Cytoplasmic granule. Note=Diffuse cytoplasmic localization, but also localized to cytoplasmic aggregates throughout development. Co-localizes with epg-2 and lgg-1 in cytoplasmic aggregates.
Domain:
The LIR motifs (LC3-interacting region) are required for its interaction with lgg-1 and lgg-2.
Sequence:
MTPLSALTSNPAPSPPPKFALGKCPATAIHVVSVLRPNRQRFCYEKTDAGDLIPHKCLICQPILTEKHISPYYAVYSDLLEDFVLFGYNTMTGKMEQFIYAFKTDCFVEVNRPEIKYNPAFLVKGNVVVALNGPEGELVVIERDCRGLLSKESTSYGQFRTLPTAALRTLTLQDLERDRWDRAANSDEVKISSGNESFDRLYAEYQKNLPRFQVRQCLHLNKEFLCVYSKTSGDYTRLEYIDETGDFQKISCTLCTCEVTESNLIPLYVERNASELVIHVHNTENNQIEQYIYDVRTFGFVQVKRNLVYDPKKITSGLNLFMAENIDNRKVYMIMRGRDGRLQKETSGSGGFEKMQPVAVKTFQVQWVEMKTEFEKKKASTERVEPQHPVQTEGEDIMETVLAMVESFNCDLRKELGLTQDQEIPRKAPRVESAETEENIVKNLEKLQIAKDPEEPTTAASEGGNTYGYQELDDTMSEGLLEKEAESKHQDANEPEPVKNVTYEPDVAAMDKKKKRRELKSRLNKINAQIDELEKRRMERAGKKQVVSSSVPSEEAAQVEAPASPALAENTNQISNEETPKIDIFEGYNGSFLFGTNTSKEWIVEDIRNHMVGKLLKAFWPRIQNVEEMNGELFKKLIANARKCETEILEASNDRDEYYRLMQLTVDQILKKTLKKDQRATEHNHQQPTQSSDELAKNHEKN
The following text describes a protein:
Function:
[Isoform Membrane-bound glycoprotein G]: Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (Probable); [Isoform Secreted glycoprotein G]: Helps the virus escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fc-gamma receptors.
Subcellular Localization:
[Isoform Membrane-bound glycoprotein G]: Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein; [Isoform Secreted glycoprotein G]: Secreted. Note=The protein is shed from infected cells before the appearance of progeny virus (By similarity). The initiation at the downstream methionine removes a portion of the transmembrane domain. The remaining hydrophobic portion of the sG protein is essential for translocating it into the lumen of the ER during translation and would likely maintain its membrane association until a proteolytic event releases the mature sG protein into the medium (By similarity).
Domain:
[Isoform Membrane-bound glycoprotein G]: Contains a linear heparin binding domain essential for virus attachment to the host.
Sequence:
MSKNKDQRTAKTLERTWDTLNHLLFISSCLYKLNLKSVAQITLSILAMIISTSLIIAAIIFIASANHKVTPTTAIIQDATSQIKNTTPTYLTQNPQLGISPSNPSEITSQITTILASTTPGVKSTLQSTTVKTKNTTTTQTQPSKPTTKQRQNKPPSKPNNDFHFEVFNFVPCSICSNNPTCWAICKRIPNKKPGKKTTTKPTKKPTLKTTKKDPKPQTTKSKEVPTTKPTEEPTINTTKTNIITTLLTSNTTGNPELTSQMETFHSTSSEGNPSPSQVSTTSEYPSQPSSPPNTPRQ
The following text describes a protein:
Function:
Catalyzes the exchange of ADP and ATP across the membrane.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MGGVAHTIVAPIERAKLLLQTQESNLAIMQGRHHRYKGMIDCIFRIAKDEGVLSLWRGNGSSVMRYYPSLALNFAFKDLYRSLLISDKNDALSRAPFNFVAGAAAGCTSLVFVYPLDIAHTRLAADIGNRDARQFKGLLHFIRTIYRKDGTRGLYRGLPASIQGMVVHRSVYFGGFDTAKDLLSRDSEHLPFWKRWLMAQAATTSAGLISYPLDTVRHRMMMQAGLEKRMYVNTLDCWRKIYRMEGVSSFYRGAVSNMLRGTGAALILVLYDELKYLMNLTVPLDSGNK
The following text describes a protein:
Function:
Nuclear-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. RRP6 has 3'-5' exonuclease activity which is not modulated upon association with Exo-9 suggesting that the complex inner RNA-binding path is not used to access its active site (By similarity). Involved in the processing of 5.8S rRNA, a subset of mRNAs and non-coding RNAs. Plays mostly a structural role in degrading some of its mRNA targets, such as early meiotic mRNAs bound to mmi1 and iron homeostasis mRNAs, probably by the channeling of these transcripts to dis3 for degradation.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MDESELFKGLMNSTAYCSELAKVDIPFYKSIDTEFNENIKSVSSRFMRLIELLLSKVDRSRAEDIVDVEDIDNRWAEVSDTLDILFEKADYSIDKAQGLLKKPAIETHASTSDVANKKPKKEKLPYKVIHAAHLTKPQLRFRVQPNNSREFVWSWKLTEKPHSLVPLEKIIAQVKLDPSLKNSLPHPYEPEIQNSVYPPWVSEMSNPIDTGSVDETEPIWVSTESQLSDMLKELQNSKEIAVDLEHHDYRSFRGFVCLMQISNREKDWIVDTLELREELEALNVVFTNPNIIKVFHGATMDIIWLQRDFGLYVVNLFDTYYATKVLGFEGHGLAFLLQKYCDYDADKRYQMADWRIRPLPREMLKYAQSDTHYLLYIWDHLRNELISKSAERKENLMQSVFNSSKQISLRKYELEPYDPIYGLGTDGWRNVLTKFGSSKIIGREALMIYRALHDWRDSVARKEDESVRYVLPNRLLIAIAASKPVEAADVFSISKQLTPIARMYVEDIVKVVQEAEKLYNEQVDREKSQFKEVEKQNQPLAVFSESNTLGDYKVDSSVFEISKQNRSKLKTLLANGSAFWIEGQSQDDLRKARKERLFIVNQNIPFSLTLPCTQGHVESELNVKQSTVTEAANPSLNGEKKQEPIVIRDLGLNKQKRDSSKLNHKEPSNPIEERNEDIEPSEASTSVSKKRKQKKKKKNSGKLTIEAEHVSNDSPIINEAPFDYKNQKNFIADLDSDVGKNKFGKRGFNPLNKVSLPKRNTRELKKRKVSDGKSTSY
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MRTANTKMLPRAAADEETREGEMGPDLLGLGLLPPPMAGGGHGGGSAAQRRPYQKTGFDEPLRFAADAPLPVRPRPRPVDVDDGVVPAAAPPASMPKPPASSTAARWAPAELASSPTKLGSFREIFQVPSTFCSDQLAAGEGCRAHAVATCASPPLMQCCPCPAAGVLFFGSRPPVTAGLIFEDSASAAVARSTHDDSTAPTTIIYAGSVCAYDGAMIEQAEKVLAMVAKEAHAAGILSVQRTEPQLELVAAITGGAAQMTMHRRLAHHVSDSLKRTASLARFLDKRKQRAESAGTMQHHPRREEWRFPAQTTDAPAATVSARTSASLGGMDRRPRASQDHPKRMKASHGDEAVSTELRI
The following text describes a protein:
Function:
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences. Required for rRNA maturation, including 5.8S rRNA processing.
Subcellular Localization:
Nucleus. Nucleus, nucleolus.
Sequence:
MATTANGNSKKRDGGLSSLAPRKINVQKFSEARAPELESLHSIVSERLNKDFRSKRNKRRRTNSYNNQPAKKRNIKRQKSQSLIGQVSGGDHEVKITRRVKRRMELKGNPETGFCTSGDGTKRLRTHVWHAKRFTMTKLWGFHLPLGLHGRGRGSRDVLKQSRQGVLVHDASYHIAVQLEGPEGSLLSILNMLLEPSPSSHSKEVFDSILTGGSYENAMLYHVEPPVSQAIAPVTYMWRPSKIPKRRNEEKGGDGIGTDLPVSDKDHEDFRKLWVWIHASSFSEGYAILKVACQKQMNETGVSVDCFSLEGQLAKLEIFGSKASHLLQKTLHPATSTSENPSILRKCSMEKAEVKNVADLYTEENVSSGAILAQFVIDPRLILTSPHDDRTVSVETIKTEPTESVETTTNTEAETFPEVFNCLWDANSELTPPEEENMLCWEKHQSRMDSLCLDDPAAEVPKVSSRPRSSRSCPLLLLKHKKLGNAPTGWSLILPLSWIKVFWNAFVSKGAHAIGQREKRWVSCDDGLPFFPSDFPDCKAYSSFTLSEAADLEEKAQRRPPAIRPFRIPIPPPWNSIHVTRSIGEGSNQKFSSNGRSVVEISSYGGNLFDGIVARTSDSLTTFLQTFTSDNMLLFPHNTSKPSTDLMMTLQEDDKKVRAQIHQSSNKLCLVRVLLHAFKEGSFEEGAVVCAPTLADISLLKSSCSEGEDGRVTIPQSSVSSYFQEQPCGTWELNVPEDTLTEQSHRWPIGFVTTGFVRGSKKPAAEAFCDAVLLGRLRDEQWRDKDVRRRKKQIYVLVRNLRSSAFRLALATIVLEQQDYCDVHCF
The following text describes a protein:
Function:
Required for assembly of the mitotic spindle.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSTIPELSRPAASPPAGTLPPLPAPKVRKSLPLSTDIQRASSPLQSTSKLRTPSSPRSNFNRSPLSSSISTQGSLRSASGGRSPASPEKSLRRTISIAAFPQPPKVNGRSSVASTISGSNNIPLGSARVKSGSRLSSGTTSSYRSSRPPSLLNGNGDSRNGASLDSREQEASPTQSRSSSAQGSYSTSATTCEDPDDATGIAKSNSRTKQAKGNVIVSVRVRPNLTGTDSSASDSDWVVDGRRGLISYKGKEGGVDYLYDNVFPPHEHNAKVYDAAAKRLVRRVMEGYHGTVFAYGMTGTGKTFSMQGTATSPGVIPLAITDIFSFIRETPHREFLLRVSYLEIYNEKIHDLLSASGSTGLGNSQQEEIKLREDSKRGVYATPLKEEIVQSPTQLLRVIARGDLARRTGSTQFNARSSRSHAVVQIVVESRERAPTSKPSQERRSGMAPGGVRVSTLSLIDLAGSERAAEDKERRTEGAHINKSLLTLGTIIAKLSENKDKGGTSADREGRHLPYRDSKLTRLLQPALSGNSLVSILCTIQIDGSGSSATTGSLSTETLNTLKFAARAKNSIVSHAKRAEEAFGSGGVDAGSRVLLERYRMEIQTLRSQLESQARDQAEKELKLEEQQLEKEAKVRHEEQMLEMQLARTALKERIEHLNRLILCSKSTGVNSHNGIAAFGRLSRMSTTGSISRSLRSSVSQSTLSACGFSSVRPVSLLSTNSTELSVNLPYRNAPLEHEEDEIMGEFADGRASAQRQIAALQADLNDKNRYISTLERRLLQARRSSHSRITMGVKSVNAPSEEPDFRALLREKDMEINELRLQLDDKDRMLAALRSAARHWDLAHVTTDPGAAGPKSKRASLNSNGGLMPSYDRAAGSFSSPESDEKEPDGKSMDEVSRILDEMIQDRVESGHLVKGSRGSVRVADEKQRALEPAAGIPALNTASTISEDGTTVM
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MSSRSSHYSAKSLSSSAGESMVTSHSTGSSSRHRRTGTVCIHEPRAPPMKMTAMELLQHIRNSITRLKYICERQYHTAALDQASEVAVTSFFERLRKKLSKLEFSRSHIGTPETGGPQQLKYIAKEARQLMSTAQEVVRDTANTSVTATCVYEGMQHHHMQEAMAELEELSALLAERPNEQPSRVSVDLLADLVAFHIDEFDAFMALRVEAFVREMQSEGAFYTGPVMTDASQKATPVGVCSAVLLDVAVGVRPARSARIVLEHARHQISKVENRLHAADIALQECQLAGEVAAEGQQRQRAEVQRREFTIMKERIRHALRQLDRVQQAWLEEEQSIFTRAASGSHDLAALMQTKHLHEAEVIEEVQRLHDQTIHACLPFATPQYHRRYGETYGQPCHVRLGFHFLPDANTAAEMAAAAGSTNAAAPSSLMLRTLSTEYFALMRQLRVAPVDYDTYDYLVPSKEQFWVNFASFPEMVKGARCALRNVDARLDHFRALEEQKEVGGYFIMNGGERILRALLMQRCNVPINIYREKFVTQGPHFSAKAVVIRCKRPSGLTAQNYFYYTTQGEVIFSFARKVVWHLPAPLLLNAMSTQSVSAVELQRLLTIGMPDGNHVARVEALLQHHRRKPYGDLRHFIDYITVLGRMYREYHQNSSTFHFLPLYAKGSTCQHDAWYGMFMVRRHVLPHLNSCDVATPDLAPDATAQKLLAWLSPALLAELDRKFDAMIAITRQLYLFIDGAVEHQGNDVPAYQELFTVSQVLMGAFEVCLNRYMRGFVYRLARHLPAALFRRILSLRTLLPPVDAEDTMRQVRQFAEFCGRHGGSDPLDQLARLLVTGNINLDREEDFYCPQTSGWVVMAEHLNFYRFFEQLRCVHRGKTIADMRSSEVRKYPCEAYGFICMVQSPDGEDCGVLNHLSVSTISSNSPDAAMTAQLREIVRKAVPGVRSRATLSTVVDQLCETVPVWMEGELLGYLSPADAVEAAATLRERKALTLRSQVHVTGIVRRKDASPLHTLEVVYVAPKSKDPAGLYVFYDCGRLMRPVQRLESSVRKDATHLPFPLVFIGTWEQSWLDIAAVPSDPLDAVVQLNRKYEYMEQNGTNLISLTSATIPFFEHNCSPRNLFQCGLSKQSSGTQLQALAWRKEAKLFRTYCPQRYISRTLPMDYYGLDDVNLGVNAVIAILAYTGYDMDDAVIINSTAAQRGMLTAGVTVAKIVTASGKGSDKDDVFVFHNLLSTGERFTAELEANGLPPKRANASLDAFSFDRDHKYPGLRDNNDVYCCAKRVERVDPFTNKAVYEYTRHHATKWRHFDKGEDAWVQQVIPLVYSGPDPTSVLMIFRIPRPPTVGDKFSSRHGQKGTLPLHIRSHDLPFATASGITPDVIINPHAFPSRMTVGMVLEIMTAKVGAIEGRFIDNSAWSTVDEQPRVAELIGEALVKAGYNRYGREHLIDGISGEEMKADVFMGICGYQRLRHMVSDKWQARARTDAHTYRAVTKTGQPVKGRKRHGGVRVGEMERDGLLSHGISEVVVDRLLHVSDKTKAFICPRCGSLLSLYERHATEYGTWRTCRFCGAGADESTDSIAMVEIPQVLRLWAAELTSIGIRVVLKTSELSDFV