lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Endopeptidase (By similarity). Plays a key role in innate immunity by activating the Toll pathway in response to fungal and Gram-positive bacterial infections, presumably downstream of pattern-recognition receptors (PRR), such as PGRP-SA, GNBP1 and GNBP3, and upstream of spz processing enzyme SPE.
Subcellular Localization:
Secreted. Note=Probably secreted in the hemolymph.
Domain:
The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure.
Sequence:
MMIASSLAVLYGIAIVSSMGVQSARADYADDCTTPDGDQGQCMPFSSCRTIEERLTEAQKAGQKVPADYASYLQKALCGEFNGVRHFCCPSANIQHNSKVMSLFKDENFDCGNFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTTENGSSSDVLLQANVPLQPRSACSQAYRRAVPLSQLCVGGGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQISLPGLYTNVGEYVQWITDTMASNGL
The following text describes a protein:
Function:
Probable protease; promotes adherence and invasion by directly binding to a host cell structure.
Subcellular Localization:
[Adhesion and penetration protein autotransporter]: Periplasm; [Adhesion and penetration protein]: Secreted. Cell surface; [Adhesion and penetration protein translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Domain:
The signal peptide, cleaved at the inner membrane, guides the autotransporter protein to the periplasmic space. Then, insertion of the C-terminal translocator domain in the outer membrane forms a hydrophilic pore for the translocation of the passenger domain to the bacterial cell surface, with subsequent cleavage (By similarity).
Sequence:
MKKTVFRLNFLTACISLGIVSQAWAGHTYFGIDYQYYRDFAENKGKFTVGAQNIKVYNKQGQLVGTSMTKAPMIDFSVVSRNGVAALVENQYIVSVAHNVGYTDVDFGAEGNNPDQHRFTYKIVKRNNYKKDNLHPYEDDYHNPRLHKFVTEAAPIDMTSNMNGSTYSDRTKYPERVRIGSGRQFWRNDQDKGDQVAGAYHYLTAGNTHNQRGAGNGYSYLGGDVRKAGEYGPLPIAGSKGDSGSPMFIYDAEKQKWLINGILREGNPFEGKENGFQLVRKSYFDEIFERDLHTSLYTRAGNGVYTISGNDNGQGSITQKSGIPSEIKITLANMSLPLKEKDKVHNPRYDGPNIYSPRLNNGETLYFMDQKQGSLIFASDINQGAGGLYFEGNFTVSPNSNQTWQGAGIHVSENSTVTWKVNGVEHDRLSKIGKGTLHVQAKGENKGSISVGDGKVILEQQADDQGNKQAFSEIGLVSGRGTVQLNDDKQFDTDKFYFGFRGGRLDLNGHSLTFKRIQNTDEGAMIVNHNTTQAANVTITGNESIVLPNGNNINKLDYRKEIAYNGWFGETDKNKHNGRLNLIYKPTTEDRTLLLSGGTNLKGDITQTKGKLFFSGRPTPHAYNHLNKRWSEMEGIPQGEIVWDHDWINRTFKAENFQIKGGSAVVSRNVSSIEGNWTVSNNANATFGVVPNQQNTICTRSDWTGLTTCQKVDLTDTKVINSIPKTQINGSINLTDNATANVKGLAKLNGNVTLTNHSQFTLSNNATQIGNIRLSDNSTATVDNANLNGNVHLTDSAQFSLKNSHFSHQIQGDKGTTVTLENATWTMPSDTTLQNLTLNNSTITLNSAYSASSNNTPRRRSLETETTPTSAEHRFNTLTVNGKLSGQGTFQFTSSLFGYKSDKLKLSNDAEGDYILSVRNTGKEPETLEQLTLVESKDNQPLSDKLKFTLENDHVDAGALRYKLVKNDGEFRLHNPIKEQELHNDLVRAEQAERTLEAKQVEPTAKTQTGEPKVRSRRAARAAFPDTLPDQSLLNALEAKQAELTAETQKSKAKTKKVRSKRAVFSDPLLDQSLFALEAALEVIDAPQQSEKDRLAQEEAEKQRKQKDLISRYSNSALSELSATVNSMLSVQDELDRLFVDQAQSAVWTNIAQDKRRYDSDAFRAYQQQKTNLRQIGVQKALANGRIGAVFSHSRSDNTFDEQVKNHATLTMMSGFAQYQWGDLQFGVNVGTGISASKMAEEQSRKIHRKAINYGVNASYQFRLGQLGIQPYFGVNRYFIERENYQSEEVRVKTPSLAFNRYNAGIRVDYTFTPTDNISVKPYFFVNYVDVSNANVQTTVNLTVLQQPFGRYWQKEVGLKAEILHFQISAFISKSQGSQLGKQQNVGVKLGYRW
The following text describes a protein:
Function:
Required for normal tracheal development and maintenance of the trans-epithelial diffusion barrier. Functions as a homophilic cell-adhesion molecule. May play a role in early neuronal differentiation and axon outgrowth.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Note=Located at the extracellular face of the membrane and becomes associated with septate junctions.
Sequence:
MWRPSISNCVWSTLLLAIFVQQTLAQRTPTISYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIPVCPPACGQAYIAGAEDVSATSFALVGILAALLFAR
The following text describes a protein:
Function:
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MHGPQRPRTHKRVTGLDTSSMLHLQPHNLLIEKTLVEALEAFRKGTPLTLDRVVSDFDYATFHISNADQTGVTLNVSMRTKAWQSVAAAGPGLLAYLQDKYDRLPGVSTASAPETGYDHTLLIQLDALAPESVMQVALLKMTTMAYVFQLAFDESLRLAQLPEDRQEAAGVHLIQYRDDENIYIKPSGDRVTVIFETMFQGETDKVFGKVFLQEFVDARKRNRSIQSAPQVLVSHEAPLEIASAVPRRTADRSKRFVTFVLFPRHFVTRDLQFSSVCHLALFRNYFHYHIKCSKAYMHTRMRRRVDSFIKVLNRAKVDAEDDDDDNRRTISGKKMVY
The following text describes a protein:
Function:
Required for red (R) and far red (FR) light-induced and phytochrome-mediated deregulation of negative gravitropism leading to randomization of hypocotyl growth orientation.
Sequence:
MLPGILLCSLNPRNHSKKKKSERESLETEPKDIDYWYSVQFNRDPPRFALKSENNNHHSRSKSGGDFCKKKKRGEMANKVSNFSDLIQRVTASCLLHPLSAGRQDLAVNRREEYDTEEEENEEEGEIQYEDALEKENGKDETIRAKNGRNGVSVETVQEMEMVMDEVFTAAAAMKRAYVALQEAHSPWDPEKMHDADMAMVAELRRIGSLRERFRRMRGTGSGGRRKNDAGRGMLREAVAPYEAVVKELKKEVKVKDTEIENLKEKVKVASMANGNGGKKHRLLSSRKVNCTTQIAVSPVPELFEMTMIQVKEASKSFTGILLSLMRAAHWDIAAAVRSIEAASASSDGMSASSFASSVQSSVPNQHAKFALESYICRKIFQGFDHETFYMDGSLSSLINPDQYRRDCFAQFKDMKAMDPMELLGILPTCHFGKFCSKKYLSIIHQKMEESLFGDSEQRELVVAGNHPRSQFYGEFLGLAKAVWLLHLLAFSLDPSPSHFEANRGAEFHSQYMESVVRFSDGRVPAGQVVGFPVCPGFKLSHQGKGSIIKSRVYLVPRA
The following text describes a protein:
Function:
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Subcellular Localization:
Nucleus.
Sequence:
MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDSTVIDHTLPTPEAAEFLKESELALRARKEEDCPEEEETEGVEDGEEGDLKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELGSGQYDMAECQAALSPVRPTHSSVRQVEDSLTFPDYSDSTEVKFEELKNVKLEEDDEDEEEEHEAAVLDLSVNPASLGRLVFSGSKEKSSSSLGSGSSQDSVSSDSETSEPLSCRAQGQTGVLTVHSYARGDGRVLPGEPCARKKGGATRSISERELAEVADEYMFSLEESKKSKGRRQPLSKLPRHHPLVLQDCVSDDELPEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNEAMAQQAPHCAVCMIFQTYHQVEFGGFGQSCGSAPDLAPQTQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSLLVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCVFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQLGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME
The following text describes a protein:
Function:
May have isomerase activity (By similarity). Enhances target gene silencing when coexpressed with antisense RNA.
Sequence:
MTEHSFKQIDVFSNKGFRGNPVAVFFDADNLSQKEMQQIAKWTNLSETTFVQKPTIDKADYRLRIFTPECELSFAGHPTIGSCFAVVESGYCTPKNCKIIQECLAGLVELTIDGEKDEDTWISFKLPYYKILQTSETAISEVENALGIPLNYSSQVSPPVLIDDGPKWLVIQLPNATDVLNLVPKFQSLSQVCKNNDWIGVTVFGELGKDSFESRSFAPLIHVNEDPACGSGAGAVGVYIGSSQKTPTSLSFTISQGTKLSRQAISKVSVDVSSNKSIAVFVGGQAKTCISGKSFI
The following text describes a protein:
Function:
Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MVTARFAFYISAVAMFRFHLWTLLRLFALLSSLVTASRIVLEEAGHLPAGWKVERHATASDRIQLSIALKEPGIEELKRRLLQQSTSDDHPNSRQFTKEEVEKHRQPDQRSVTAVGRWLQSHGIKSYNADNSWITFKATAATVQMLFEADLAYYSYNGDPSTQILRSRSYTIPRWLSDDIDFVHPLTNFMPPRNRNDGTLGIGRRQPIQPKLSAREDFFAPPCWTGTFPGCIRKLYNLTYTPSPDFRSPSPVRFGIASFLEQYITHRDVTSFLATYARELLPLRPTPSRGGSGGSLTLPPVTNTTSEPPYNITITLLNNATRWDPHSTDPALSGLEANLDVQYALSLGHPTRVIYYATGGRGTKLDSSGRPLPTNDPRANNEPFLEFLQALLALPDNQIPHVLSISYADDEQSVPRKYAHRVCDLFAAVAARGTSVLVATGDGGAAGIGFSAGGGDTCIKNDGSGRRAFVPTFPASCPWVTSVGATDNTALNLTGAAFSSGGFSEYFDRPLWQRAAVDPYVSSLLRSRSSKPGQPSQPRDLKGVYFSHNGRGMPDMAAIGSGFQIIHRGEMVEVRGTSASTPVVAAMVALVNDQRLRQGKRSLGWLNGHLYLDPRVRRVLTDVKWGRSEGCVFPGEALEEGRGKGKEKYWRHSVVEKRQGNSEEDGGTHGGDGEGKADEEDWGGEGEVGEGEGDQSENVILGGWDARKGWDPVTGLGVPGDFQEMLKVLGSVW
The following text describes a protein:
Function:
Chromatin anchor protein which binds to methylated lysine residues on histone H3, thereby recruiting heterochromatin to the nuclear periphery, especially in embryonic cells, with a lesser role in differentiated cells. May be required for the correct positioning of chromatin and nucleoli in embryos.
Subcellular Localization:
Nucleus inner membrane. Membrane; Peripheral membrane protein.
Sequence:
MAKKTVEGEHGTPKTNFTKKETSKNHDDFKKIIGHKVVEEHYVEYEVELTSGKTITATEFDFKGDDSLLSTYKKKVTKQSDDSSGEYAVERVLAHRKVKGSPLYLVQWKGYPHPVWNSEMWEEDLDNCKDLLAAYKKHQEDLKIAQTPKKTPSKTPKKTPKSLKRRALTPSDDEEEAGPIAPEPKKTPKQSTKKLKRTTSPETNLVEKSKKKAIPDLENHTLDQEKNDVIERVEEIQEDEDDDDEQREEVVTTAPVETKSRWGFGSWKWF
The following text describes a protein:
Function:
FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Bacterial flagellum basal body.
Sequence:
MTDQQIELNNDLDFTLALDESAISPTEHFDSVINSPEIINTPEKTATKTDEQKRKMSLFSRIPVTLTLEVASVEIPLSELLTVNNDSVIELDKLAGEPLDIRVNGIMFGQAEVVVINEKYGLRIININSQNLGELAL
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSDKERERERSQSRERSRTRERSRTRDSKRDHSDSRSLRRRSYRGDRSRSPSRSRSRSYSPSRSPRRKRRRHRTSRRSRRSRREGDGRRKDGPRGHDDRSPLAPREVEDVTVKREDSTNDKESTHDKESTNDKERNVSMEDRKDTSEDVVEDVEEGDPSEEALEKKVKNPEDDLEAAAEELKKLMELKSGGRYVPPAKIRALQKLLVQDKTSKEFQKIQFDNLKKAINSLVNKVSAQNIRDIAGEIFTHNLIRGRGLFCRSVMTAQSLALPYTPVYACLTAIVNSKLPQVGELLVRRLILQFRRGYKRNQKDVCLSSVTFLAHLCNYHVAHEVLVLQLLHLLLETPTDHSVEVAVAFIKESGAFLAEVSPAANNGVFERLRAVLHDGELEKRTQYMIETLFQIRKDGYENYPVVQEELDLVDEEDYVTHMTGLDDKFTDDKLLNYFVMDPDYEANEEKYDLLKKEILGDSDDEEEDDSEAEEEADDEEEEEGDEEEEAQASTSAVRDLTGTELATLRKKIYLTVMSTMSIDEIVHKLVKLSRTVIEIPEGLPEDQALILRLKRTQEVTNMLVECCAQEKIYNKIYGGTGERLLRLSREWRTNFENTFGFFYSVIHRYEPNQIRNIATFFGYLLASDSLSWKVLEAVSLTEEDSNPSNRIFLKIMFTEMRQELGMDLLKERLSKPFVQQYIAGMFPKTNASHVRFAINYFTAINLGPLTDGMREILPGLVEEEERLKKEEEEQKREYDSYDSYDSYDSYDSYDSYDSYDSYDSYDSYDSYDSYDSYDSYDSYDSVSEDDRGRRRRRGVGSRRRSLTRSPGSRSRPRSRPRSRSRSRSLSRDRTGSPPRGRRRSRSYSRSPSRSYSRSRSYSRSPSPRPKSKGAKGRSSYRAASYSRSRSPVRRVGYSRSRSPSVSGGSSRSPSRSPCRSPNKGRAPTPEKGLSPPRKRVRASDLF
The following text describes a protein:
Function:
Involved in mitotic spindle assembly checkpoint signaling, a process that delays anaphase until chromosomes are bioriented on the spindle, and in the repair of incorrect mitotic kinetochore-spindle microtubule attachments (By similarity). Required to prevent chromosome segregation errors during meiosis. Required for fin and heart regeneration.
Sequence:
MDEEESTERQMQIAMLCQKLAMMKQLFNEDDTDYINQAISSNSPDTCRTFLSNLEKKGNPQADPSLLSKLMDSYTRVFSSMPLGKYSQNESYAKMLVRFAELKAIQDVNDAQTSFDIARSHCKDFAFVHVAYAQFELLQGNMKKCTMILQKAFEMNAKPRHVLEAAVRNLKTGKRQLLSHEDKENLSVSALDHTQGSRRSDGTCELKPSNTFLHSDQKFSPQEENGPVWRTGSQHRRTAMAERVPMVPLSIPENETSDSDCAQKAEAPFTHSSGFSRQTSGSSVRSAFSLCSSKKGTPDGDSYSLNIKPPVISPDYLREDIEEGHTITALLNRAEKRETARTEETTDINQIISTNSTEGCQAFLKNLEKRADPHSDAAFLSKLLDCYSKVFARFPLAEHCKTESYARMLVRYAELKGIEDPEDAADDFSIARSHCKAFAFVHIAHAQFELSRGNSRKSVSILQKALSSNARPIELLQTAIRNLKSGKTLLLPAEHQESSEAENVEAQNGMKREENPVKAPEDHQKPFSKETSSEWKIPALITKHTSPEDRKAPVEPVSSSSSHHAVRTPAPLRLNPSLSCQTPNYRQPNPNSFVTPVVKQRPVIVSVPATAQKMCPTALPCTPQSGVSYIQPPTQTPSSAFSNESITIKGKQFFIFKMIGRGGSSKVYQVFDHKKHVYAVKYVNLEEADAQAVESYKNEIEHLNHLQQYSDQIIKLYDYEITSSYIYMLMECGHLDLNTWLRNRKTVKPLDRKAYWRNMLEAVHTIHKHGIVHSDLKPANFLIVDGSLKLIDFGIANQIQPDVTSIMKDSQVGTLNYMPPEAIKDTSSNGKPGSKISAKGDVWSLGCILYCMTYGKTPFQNITNQISKIHAIIDPSHEIDFPDIPEKDLLDVLKKCLVRNPRERISIAELLDHPYLQLQPQPAPEPAETSSSDFKRILNELVALQSPNSIARAASNLAMMCNSGRKLDVSECVKSSSQTLWK
The following text describes a protein:
Function:
Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
Subcellular Localization:
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Preautophagosomal structure membrane; Multi-pass membrane protein.
Sequence:
MDIEERESKEREQERERERERDPFRNFDESRSSSTITQLNLEQQSTLLEQSQSILSILTRPTTTTNNNHSDSFNQSASSSQNSQSNHPLHQIQDGGPPQSIMIDIDYQQQSNSKSKSTAQNQQTTDDQGYQTENSSSPTPSLTRHQEQEQEQSDQPHQSILHDHRPPSSLLLPPNHHHHQYPRSNLEEEEESNNQATPFRSGLLSRLKQIWNQERDQYFSNQQHRTSHQLNSFSHHNQSASDREQQGQHDNNLQQAHQTLGAKEMALWRWVNVDDLDSSSRTSIAITTVGFVIGFSIFLFGCIDYSILRSSHHLHEVIVPQCVSRFSGLSLLLVLAFSGYYSWRVLKFGQEISNLWKMHEFFTELLEVSEADIQTIPWYRLVEQLSRLKDQHPATIATGESEGRRRAMGTPHMQSVLQRKLDAHDVANQIMREQNYLIALFNKDILNLRPPLPNWMVGNFLIAEKHLTTSLEWNLLFSLRGFLLDRRGQVKPEFLVSSRFEPSMALGLQRRFRLMAIINLIFGPFIVIYVLIYSFFRYFEEYHKNPASIGSRSFTRLAQWKFREYNELPHLFQERLVSSCCLSKQYIDQFPKTKTTILAKFVSFIAGSFAGVLILLSLYDPDAFLHFEITPERSVLFYIGLFGSILAISRGMIKQEYEEKIERPGDLMERIVGLTHYLPSHWYGKLHGLDVYNDFGSSQLRI
The following text describes a protein:
Function:
Possible regulatory or functional link with the histocompatibility cluster.
Sequence:
MPPRKKPFSGKAKKQQLRDKRAKKRDAQDSGNEDDRAAEWTAAPPAPQTVGDVVVLPKSELQSDAQSVGMQVSSGRGDLRTIFQKESKAAIEARKRDATRELVYAQDRGNSQSIYAYGIQDPANQSRILTKPKWSRDMTPEELNEVDDRAFKEWVEYLEQEAENREDGAQINLYERNLEVWRQLWRVIERSSVLVHLADARCPLLHISDQLMTHIRTKFPWKRVVLVLTKTDLVAEERIQKWSNYLQARYGQGIPVLAYSRDRVDESNAVLMRTIGQVSAGIEHRELNDDPTAEEGQKDTLTIGFVGEPNVGKSSLLNSLFDRKLVSVSATPGHTKHLQTHYFDRVEMLEREDGIFSRVLVFDCPGVVFPRFNVPVLLQILFGSFPIAQTREPFSAVRFIAENCSPYLHDVYKLKPVEDDDEEWCPYTLCEAYAQLRGFRVKGGKLDVHRAANMLLRDTLTGKKVVLSFPPPLATRVLRTPQHMRGFPAAAEKVEEDLPAAACHREAKGPDCWKCHHATDCCSFFCKSCNAIQPIDKGCHCDYFEMFKIPKHFNLEQRSIEKTYWNLQKRLHPDLYGSKSEFEKELSAVNAAVINDAYKMLKTPNTRVKYLLALHGIDALGETASTAVDPELLMQTMEIRERIAEAPDVDALHEIRKEISEHIDAVINKLGEVYDKDQDLEATKQYAVELQYMVKCAEEIDLREEKLDGY
The following text describes a protein:
Function:
Probably involved in transport through the plasma membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSAQEFYQGGNQRGYQQQQFPPPPGGPPQDQNGGKQEYVPPQGQPPNYNMKPSQPYASTNPETGGQPVYQDTAPFSQANEKTGERMNPRKRVNDIIPLILFIAAVVGFAVVSGIAIHGFVQVNGLGGGMGDSSIGRTGSSITLDYHTVYLLLVVVALGLVIASLYLAALRAFTKIILEVTLALTVILNIGICIYYFIIQYWSGAIIFLIIALVSVFFYWGMRKRIPLAKLLLQTTIDVTKHHPSVYVVVFIGLIIQAAVSVWYTFTCIAIYVKWTPGSAACSDGGCSSSKVAGLVFYATFSYLWLSQVIGNVILCTLAGGVFGGWYYYGPRTPGGGVPKRASLLAFVRASTLSLGSIAFGSLLVTILELLRLILQLFRQYEAGQGDMIGSILICIAQCCIGCIQWMVEYFNKYAYIEIALYGKSYIPAAKDTWRLLKDRGIDALVNDSLVGTALMWGAYINGFLCAVLGYFYLRFTHPAYNSDGQYSAPVILFSFLIGLNESFTVGSAIDAGVSTIFVGLGEDPMVLAERSPGLFEMIRQVYPRVVQGVPH
The following text describes a protein:
Function:
Catalyzes the oxidation of hydroxylamine to nitrite. The electrons released in the reaction are partitioned to ammonium monooxygenase and to the respiratory chain. The immediate acceptor of electrons from HAO is cytochrome c-554.
Subcellular Localization:
Anammoxosome.
Sequence:
MRIGEWMRGLLLCAGLMMCGVVHADISTVPDETYDALKLDRGKATPKETYEALVKRYKDPAHGAGKGTMGDYWEPIAISIYMDPNTFYKPPVSPKEVAERKDCVECHSDETPVWVRAWKRSTHANLDKIRNLKSDDPLYYKKGKLEEVENNLRSMGKLGEKETLKEVGCIDCHVDVNKKDKADHTKDIRMPTADTCGTCHLREFAERESERDTMVWPNGQWPAGRPSHALDYTANIETTVWAAMPQREVAEGCTMCHTNQNKCDNCHTRHEFSAAESRKPEACATCHSGVDHNNWEAYTMSKHGKLAEMNRDKWNWEVRLKDAFSKGGQNAPTCAACHMEYEGEYTHNITRKTRWANYPFVPGIAENITSDWSEARLDSWVLTCTQCHSERFARSYLDLMDKGTLEGLAKYQEANAIVHKMYEDGTLTGQKTNRPNPPEPEKPGFGIFTQLFWSKGNNPASLELKVLEMAENNLAKMHVGLAHVNPGGWTYTEGWGPMNRAYVEIQDEYTKMQELSALQARVNKLEGKQTSLLDLKGTGEKISLGGLGGGMLLAGALALIGWRKRKQTRA
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC) (By similarity). May have a role in the organization of the inner nuclear membrane proteins at the nuclear envelope together with Nup154.
Subcellular Localization:
Nucleus, nuclear pore complex.
Sequence:
MEPMNLGSPVNSPGSNQTQYLPPFLLGDPQGITPHKNTLSPKTGRSNISFATSPGGSSPHELNRSALSTRTLFAAQGGAHTAVGANSSTTAHGQTHSHHQTGPPTQGLFDSLREQSVTPKKKNHLGMLQLQSPNQSYQSSYHTNDSFAPGAPNAINASMRALCSPLGATASPAGGLGTSVTTGGNSRLSDFWVTIFGFPPGAGSMVLQHFTVCGTIVDVVHAPQNGNWMYVRYSSRIESDKALNYNEKIIAGNVMVGVSRCTDRSVIDKENIGSVPNAEIGDPPTSPSAIRPFSQQSYKLARKDNIISPQKDVPQKSSGLMDKAMDLIFGW
The following text describes a protein:
Function:
Molecular adapter that is necessary to a form a stable 2-oxoglutarate dehydrogenase enzyme complex (OGDC). Required for incorporation of the E3 subunit (LPD1) into the E1-E2 core (KGD1-KGD2) of mitochondrial OGDC, and acting as a stability factor for the fully assembled complex.
Miscellaneous:
MISCELLANEOUS: Present with 2050 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MIATPIRLAKSAYEPMIKFVGTRHPLVKHATEVVVHPCATNGMLPGSKECIPVSKFMENYKPFRVVPIKHSANAGLSSSKTSVFVNRPLQKDELASIFELPARFRYKPINEHELESINSGGAW
The following text describes a protein:
Function:
Probable oxidoreductase.
Sequence:
MLDLTVNLSSLGFESGLSEDEKELLFLRSRSVGLTISGCAHAVFVCELFSLLRKKLNAENGCVNKAHLSVGILGGGNMGKQLAMALIRTSNLRSCDINLSTKRPETLGEISNMGVECYFDNIRLAKWADLLFLCVLPSHLPQVCSDIHCHLPSNCLVYSFTSAVPLNRLLMLLDHNFIIKPQYKFVDYDDVTSVWLLHNQVCTALKDKLVHSATVPLSMKGGLFLDRRWTSAVLYALLNMCTAEKLDSGNTLQLLNGLFETGVSTETFTYHSFVNSPNATSDVHKPDELFPWISLVNAQTKDTPLTDLLSRNSGLRDCISCMYYNVFANLAEG
The following text describes a protein:
Function:
Required for normal beta-1,6-glucan synthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MQNVASWLLALVVAVVQGELLPGKSAPALLWSYKLSEGIQEYQLAYNMTTVLPAPEFNAIALELLDHCNSHAYVFVNQPGLRLEDFDYEDAWTVLPNYLSRSSSALRFEQVEVSPSNVFENLIAHTKRRCDVQREIILRAEQTNQFEPYIDAQSRIIQVHFSPLPGDGRNERPSREDVLADHDQRLRRILGRLPSPAVTVIYTSLEPADRLSASPPRAGIFPEIFEHESRRIEYERNDRDLQVNRYFPSHHPKMEPIEEVELSLLDPKFIQSNLKLLKLIAVSAIGSLTWQLYSLFSPKLPVATPKGTAKRQKGQKKLVKLATAQAAKQAEEVKLEVSQQEKED
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MASVAAKREGPQFISEVSVRGNGAVLDYCRTSVSALSGATAGILGLTGLYGFVFYFLASFLLSLLLILKAGRRWNKCFKSRRLLFTGGLVGGLFTYVLFWTFLYGMVHVY
The following text describes a protein:
Function:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
Sequence:
MSKTIQANNIEALGNAMDLALERDPNVVLYGQDAGFEGGVFRATKGLQKKYGEERVWDCPIAEAAMAGIGVGAAIGGLKPIVEIQFSGFSFPAMFQIFTHAARIRNRSRGVYTCPIIVRMPMGGGIKALEHHSETLEAIYGQIAGLKTVMPSNPYDTKGLFLAAVESPDPVVFFEPKKLYRAFRQEIPADYYTVPIGQANLISQGNNLTIVSYGPTMFDLINMVYGGELKDKGIELIDLRTISPWDKETVFNSVKKTGRLLVVTEAAKTFTTSGEIIASVTEELFSYLKAAPQRVTGWDIVVPLARGEHYQFNLNARILEAVNQLLK
The following text describes a protein:
Function:
A acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MEAEVASFVEHELNDVDLKSWRSIKESLDSFLTILPTILGFVLSRLLCGHLPMLSTRRFLLELFLIGLPTVILITVGSAYSYTYSLVVSLAVLVYIYGNVAPNPPNFVYKVGKRPIVFTLLRATAYSGTCAAILAVDFPSYPTDYRKSRTFGAAVMDMGIGLFVVTMGLVSHRARSITDLKKLRRSVIPLLVLGLARTIVITLIDYHQDETEYGRHLNAFFILGFTKLLGSCYSLLVNSDEQLLALAIGLLFLHEVVLQLGLSEFVMSSAPHEGFFSANREGLSSLHGCVALYLLSIYFAKWYTSRDSLTYQGLIRKLKSILFVAILCWKLVFISSFLTGIARVTFSFGYVIWIFAVSLSLIVIYAFFFELKLVRPDICSKKSIRDDGQKNISLPTFVESLNMNGLTHFMISNFLTGMVNMSLNPGHRSDLESVVILSIYMFVCAGVVFLMLKKGIRVA
The following text describes a protein:
Function:
Part of the Sec61 complex, which is the major component of a channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). The functional states of the translocon complex include co- and post-translational ER import, cotranslational membrane protein integration and retrograde transport of misfolded proteins out of the ER. In the cotranslational pathway, ribosomes synthesizing presecretory proteins are targeted to the translocon by the cytosolic signal recognition particle (SRP) and its ER-localized receptor. The association of the Sec61 complex with the ribosome is mediated by the 28S rRNA of the large ribosomal subunit. SRP-independent post-translational translocation requires the association of additional factors, such as the Sec62/63 complex and KAR2. In an initial step, the signal sequence seems to bind simultaneously to SEC61 and SEC62. A cycle of assembly and disassembly of Sec62/63 complex from SEC61 may govern the activity of the translocon. SEC61 mediates the association with the ribosome.
Miscellaneous:
MISCELLANEOUS: Present with 24800 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSSNRVLDLFKPFESFLPEVIAPERKVPYNQKLIWTGVSLLIFLILGQIPLYGIVSSETSDPLYWLRAMLASNRGTLLELGVSPIITSSMIFQFLQGTQLLQIRPESKQDRELFQIAQKVCAIILILGQALVVVMTGNYGAPSDLGLPICLLLIFQLMFASLIVMLLDELLSKGYGLGSGISLFTATNIAEQIFWRAFAPTTVNSGRGKEFEGAVIAFFHLLAVRKDKKRALVEAFYRTNLPNMFQVLMTVAIFLFVLYLQGFRYELPIRSTKVRGQIGIYPIKLFYTSNTPIMLQSALTSNIFLISQILFQKYPTNPLIRLIGVWGIRPGTQGPQMALSGLAYYIQPLMSLSEALLDPIKTIVYITFVLGSCAVFSKTWIEISGTSPRDIAKQFKDQGMVINGKRETSIYRELKKIIPTAAAFGGATIGALSVGSDLLGTLGSGASILMATTTIYGYYEAAAKEGGFTKNLVPGFSDLM
The following text describes a protein:
Function:
Required for ciliogenesis and for structural integrity at the ciliary tip.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole.
Sequence:
MSLASGFTSVFCSSEDPSYPFENLFKDDIPAGWISMPNPSFPIESIVDMKAPFVMNGLDIVSHEFMIANRIDLFGTLDEKLDKKTQWFSIGFFTFNTNQRSQWVARELKHVTIENVTVRYLRILIEGVHDVPPNRDNRCALISLTFNGHKEIKPRMTGLSELVEDLTNAKIAAVEEENYSTAAQYKDQLLNIEENKDELTTLFNQKVEFLKQEEYLEVENVMQRINSIIKRPRDEIEEPIEEIPQHPITITEPIPEPIPEPTPPAVSVEEQPLQEMPQTDTLIQVNEDAGFFLTGFDKNTTIAIAPEEPVEQPPPEEIPEEPPQPSPVEEEPEPLPPPKKQRSIDVQDSPRRIAPPKERVPRFSKPPPDSPPKNDTPDELSDEHKSEAATLISLFGEKVVAIAYSQNWSLRVQGLEKLCELIKGLKTKPEQTRALSGILPLMRRRFGDGLKATYCAAVEQMINILEALKVEGAELGSAVHVLFPIALSKVGDTNVRIDEVSNTFVLWCADKDKWAREELQQYAIKSPPSNQYHLQKAKLILIEKIIEKYGIGDKGKVKLGEVMGLVAPCLDSRKEEVRKMAIKLTISLQQKYGTAIEKYMKNVPRLVKDQLAAATANTDAH