lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Storage protein that may function as a nutrient supply to compensate for lack of dietary proteins during metamorphosis and egg production (Probable). Has a secondary role as a nucleolar protein that may be involved in oogenesis.
Subcellular Localization:
Secreted. Nucleus. Nucleus, nucleolus. Cytoplasm. Cytoplasmic granule. Note=Localizes to the nucleus in a punctate pattern closely associated with chromatin. Localizes in foci within the cytoplasm of some cells of the fat body; these are probably cytoplasmic granules formed by endocytosis of hexamerins. Colocalizes with RNA and the nucleolus marker fibrillarin in the nucleus. Localizes to the nucleolus in the precursors of oocytes, nurse cells and follicle cells during oogenesis; this localization is maintained in differentiated nurse cells and follicle cells but not in the oocyte. Punctate localization in the nucleus of brain cells.
Sequence:
MRYFIILLALVALGVCAPNVKQRAADQDLLNKQQDVIQLLQKISQPIPNQELQNLGASYDIESNSHQYKNPIIVMYYAGAVKAGLVQPQGTTFSNSISQLRKEVSLLYRILLGAKDYQTFLKTAAWARVHVNEGQFLKAFVAAVLTRQDTQSVIFPPVYEILPQHHLDSRVIQEAQNIAIQNTQGKNNQQNILIPVNYSALLSHDEQQLSYFTQDIGLAAYYAQVNLAGYIQEQNQQQQQQPLTQQQYQQQIVGKYLQQQAGQQDQQANIGRGAQYLYLHQQLLARYELNRLSNGLGPIKDIDYENVQSLYQPHLRGLNGLEFAGRPQNLQLQSQRNQLIQYVATLEKRLRDAIDSGNVITPQGVFLSLYQPQGMNILGDLIEGTGRSVNPRYYGSLQAAARKLLGNAPEVENIWDYTPSSLELGEVAVHDPVFYQLYKKVMNLYQQYQQSLPVYQYNDLILPGVTIQNVDVSQLVTLFTDFYVDLDAVTGHQSQQQQEEQTQSRVRAHLKRLDHQPYQYKIAVHSEQNVPGAVVRVFLGPKHDHQGRPISISKNQHLFVELDQFIQNLHAGENTIIRNSQQAPGQSPDWPSTSQIQRGVNAAIRSQEPFYITEPHQIFSFPARLSLPKGQPQGFPLQFLVVISSSNPLNVPYGPVIPEQSLTYQDQQYQVVSVEQYQQLKEQGQISQVGGGIQQNVEVLPENLVNAQQQVQAVRNYYANLYTKYHGQYPNTQIQNPVGQGQDMTYSVQGVGVVNAGGWLGQQGNSWSQQQVQQAQQVQQQMQAAMAAVQQSQQRHQHAAQMIYGHQQSHHGLHINSSPSSVQSGQQQQSVLQGLGVQGVQQGVQGVQTAQGVQGVQGVQGVQGVQGVQGVQGVPGLLQGVQQVFGQGVQGMNVPYGMQRGQSGGQTWSNSQVQGVAVPGSGIVASGQQHAGGWQSIYAQPQTVQDQIVSEYYQNKPISEVIGGAISLDGKPLGFPLDRPLSLGALSVPNIFVKDVLVFHQGQPTNDITQ
The following text describes a protein:
Function:
High-affinity gluconate transporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MNRFITSILVVFISMSGWLQGADTGSISGILGMRDFQSRFADRYNPISNSYSYSAWRQALLTGTINAGCLFGAMLSSPFTERIGKKYSICFFSGVYIIAELLLVTAVPSWIQVLVGKILAGVGIGALSVLSPGYQSEVAPPQIRGAVVATYQIFSTGAALVAACINMGTHKLRKTASWRTSFGINMLWGILLMVGVLFLPESPRYLIYKGRDEEALRIMCNMAELSPESEIIQTNFNTIKSDIEIEMAGGKARWIEIFGKDIRYRTCLGFLVMLFRELIGNNYYFYYATQVFKGTGMTDIFLPAVILGAINFGTTFGALYTIDNLGRRNPLIFGAAFQSICFFIYAAVGDRKLIYKNGTSDHRAGSVMIVFSCLFLFSYCCSWGPMGWVIVGETFPIRYRSKCASVATSGNWLGNFMISFFTPFINNAIGFKLGYIYACINLFSSFMIFFLAKETKGLTLEEVNDLYMSNIKPWESYKYVREIESHRIHFSKEEEKREREKSKGIRGQEEEFIENADEDNNDSSSSSGSVVSAVKPRRSAVSNDRFSEDSHPTYI
The following text describes a protein:
Function:
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKGNIMQLSHTELQSRKKKIAWWQSDALKWLVISLLSLFTCYLIVLMYAQGEYLFAIVTLILVSLGLYVFANRRAYAWRYVYPGVAGMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLLDRQFQTGKTFTFGLYPSDNQWRLQLTNPDDGSLFISEPFSFEATGEQKVMVAPTNTAQTSEPASLRIITQSRQALSSLVAILPDGAELRMSSLRQFSGTKPLYTLGADGKELINQQTGVKYWPNPSTGFYQAVNADGQWENEKLSPGFTVSIGWKNFLRVLHDEGIQKPFISIFIWTILFSVMSVTFTVAVGMVLACVVQWDSLKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINLMLSHLFGIKPAWFSDPITAKSMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFRITFPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTSTPAGYTDLLVNYTYRVAFEGEGGQDFGLAAAIATLIFILVGALAILNLKASKMNFD
The following text describes a protein:
Function:
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
Sequence:
MRLFAAVLPPEDVTAALAAEVAVLRGLPGAEGLRWTGRPGWHLTLAFYGEVDDELVPELSARLARAAHRTAPFELALRGGGQFGRGRALWAGAEGGLATLRLLAGRAEAAGRRAGVATGEHRRYQPHLTLARSRQACDVRPYVEALAGFTGPTWTVTDLALVRSHLPESGVPGEQPRYEAVARSPLGSSG
The following text describes a protein:
Function:
This calcium-binding protein is found in the basal body complexes (the functional homolog of the centrosome in animal cell). In mitotic cells it is specifically associated with the poles of the mitotic spindles at the sites of the duplicated basal body complexes.
Sequence:
MQAVGPGSTLAFGRTPVVRPAARRDLTKDESEAVLFAFETLDAERTGSVSRKQLKVALRALGFGVKKADVADLLARHGEESTQQLDFQTFRRVVADMLCQRTPLDEHRRAFQLFDVLGQGAIDFVTLKRVAKSLNLDIPDEELQDMIHEFGKDGLITEQDWLAIMSAD
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Positive regulator of shade avoidance and of jasmonate signaling. Acts in repression of PhyB-mediated light signaling and regulates the expression of FLOWERING LOCUS T (FT) and of CONSTANS (CO).
Miscellaneous:
MISCELLANEOUS: The affinity between DREB2A and MED25 is reduced when DREB2A is pre-bound to DNA.
Subcellular Localization:
Nucleus.
Sequence:
MSSEVKQLIVVAEGTAALGPYWQTIVSDYLEKIIRSFCGSELNGERNPVSTVELSLVIFNSHGSYCACLVQRSGWTRDVDIFLHWLSSIQFGGGGFNEVATAEGLAEALMMFSPPSGQAQPSNDLKRHCILITASNPHILPTPVYRPRLQNVERNENGDAQAESRLSDAETVASYFAKCSVSLSVVCPKQLPTIRALYNAGKPNQQSADLSIDTAKNTFYLVLISENFVEACAALSHSATNLPQTQSPVKVDRATVAPSIPVTGQPPAPVSSANGPIQNRQPVSVGPVPTATVKVEPSTVTSMAPVPSFPHIPAVARPATQAIPSIQTSSASPVSQDMVSNAENAPDIKPVVVSGMTPPLRTGPPGGANVNLLNNLSQVRQVMSSAALAGAASSVGQSAVAMHMSNMISTGMATSLPPSQTVFSTGQQGITSMAGSGALMGSAQTGQSPGPNNAFSPQTTSNVASNLGVSQPMQGMNQGSHSGAMMQGGISMNQNMMSGLGQGNVSSGTGGMMPTPGVGQQAQSGIQQLGGSNSSAPNMQLSQPSSGAMQTSQSKYVKVWEGNLSGQRQGQPVLITRLEGYRSASASDSLAANWPPTMQIVRLISQDHMNNKQYVGKADFLVFRAMSQHGFLGQLQDKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDMVVFKPQIPNQQQQQQQQLHQQQQQQQQIQQQQQQQQHLQQQQMPQLQQQQQQHQQQQQQQHQLSQLQHHQQQQQQQQQQQQQHQLTQLQHHHQQQQQASPLNQMQQQTSPLNQMQQQTSPLNQMQQQQQPQQMVMGGQAFAQAPGRSQQGGGGGQPNMPGAGFMG
The following text describes a protein:
Function:
Part of the yadCKLM-htrE-yadVN fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches.
Miscellaneous:
MISCELLANEOUS: The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.
Subcellular Localization:
Fimbrium.
Sequence:
MIKTTPHKIVILMGILLSPSVFATDINVEFTATVKATTCNITLTGNNVTNDGNNNYTLRIPKMGLDKIANKTTESQADFKLVASGCSSGISWIDTTLTGNASSSSPKLIIPQSGDSSSTTSNIGMGFKKRTTDDATFLKPNSAEKIRWSTDEMQPDKGLEMTVALRETDAGQGVPGNFRALATFNFIYQ
The following text describes a protein:
Function:
Methylates ribosomal protein L11.
Subcellular Localization:
Cytoplasm.
Sequence:
MRYREIILSIPKEIAENFTSFLDEVGVVGYYEILFDREVPRAPDEEIISDDTKFRVYLAEEDKENETKILIFLKATAGESFFLESRWIETKEYEEAYKEFYKPFIIGSYRVIPTWEKDTALGTTPEGIFPLLVNPGLAFGTGHHETTRLVLGRMGDLNLSAKRIADVGTGSGILSLAAAKSGASLILAIDVDPNSVRSASFNRDENEISSEVLVVEEGGFDHKKIQEQTWDLLIANITFAVLKANIQKIASIKTDHFLFSGVITERKEEFLELLKNTVGGEGVFFREDTGWELIEWKRKG
The following text describes a protein:
Function:
Stress-induced phosphorylation of CAPZIP may regulate the ability of F-actin-capping protein to remodel actin filament assembly.
Sequence:
MEERPAETNANVDNSASPSVAQLAGRFREQAAAAKETPASKPTRRKPPCSLPLFPPKVDLGQNGEEKSPPNASHPPKFKVKSSPLIEKLQANLTFDPAALLPGASPKSPGLKAMVSPFHSPPSTPSSPGVRSRPSEAEEVPVSFDQPPEGSHLPCYNKVRTRGSIKRRPPSRRFRRSQSDCGELGDFRAVESSQQNGAKEEDGDEVLPSKSKAPGSPLSSEGAAGEGVRTLGPAEKPPLRRSPSRTEKQEEDRATEEAKNGEKARRSSEEVDGQHPAQEEVPESPQTSGPEAENRCGSPREEKPAGEEAEMEKATEVKGERVQNEEVGPEHDSQETKKLEEGAAVKETPHSPPGGVKGGDVPKQEKGKEKQQEGAVLEPGCSPQTGPAQLETSSEVQSEPAVPKPEDDTPVQDTKM
The following text describes a protein:
Function:
Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
Sequence:
MEKYKLLVSDPIAEVGLNKLKEFFEVNYKPGLPKDELLNIIQDYVALVVRSETKVTKDVIERAKNLKVIGRAGVGVDNIDVEEATRKGILVINAPEGNTIAACEHTIGLMLAISRKIPQAFSLLRQGKWERKSFIGNELYGKTLGLVGLGRIGSEVAKRAKSFKMRVIAYDPFISPEKAKELDVELYSDLPALLKEADYVSLHLPLTQDTKNLIGKKELEMMKPTAYLINCARGGLVDEDALYEILKEKKIAGAALDVFKNEPINPDNPLLTLDNVVLTPHLGASTQEAQEKVALIVAEEIIRFFKGEMVSHAVNLPIQISPEIMPFAKLGEKLGKLLAQITNANPEELEIQICGDLAQRIETSLASAVVKGFLEPILGEEVNLINAMAMAKDRRLRIVEVRTEEINTYRSSIRLRLKTEKGFIEVSGTVSRNQERILAIQDYHLDLALSQYMLIAFHIDRPGIIGQVGTVLGKNNINIAAMQVGRKEIGKDAVMVLVIDNPVDDKVLRELKNIENIKEVYYVCL
The following text describes a protein:
Function:
Needed for flagellar regrowth and assembly.
Sequence:
MLLRKDEVFYIDLPRKIEKEEKVKEEKTKENAAEEIQRIEKMREKILSEAQEEARKIIEGARKDAEEILSNASSEAEALKLEAKKVLEEAKTMKNDFQKYILALKEKIQKQVNQRIEEILPELLDILRILFKKILEKEMDESTVERKLRSALSKVVGIKNVKIRINPEDAKKLDLSEVSKETLIPDPNVERGGVIVETDFGILDKTFSHQWELVEDIFEEVVGFEGHPERAEKEVE
The following text describes a protein:
Function:
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MNMSVLTLQEYEFEKQFNENEAIQWMQENWKKSFLFSALYAAFIFGGRYLMNKRAKFELRKPLVLWSLSLAAFSIFGALRTGAYMVYILMTKGLKPSVCDQSFYNGPVSKFWAYAFVLSKAPELGDTIFIVLRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAMMYSYYALRAAGFRVSRKFAMFITLSQISQMLMGCVVNYLVFSWMQQGQCPSHVQNIIWSSLMYLSYFVLFCHFFFEAYIGKTRKAAKVD
The following text describes a protein:
Function:
Beta subunit of a hydrogen-evolving hydrogenase that utilizes protons both as a substrate for hydrogen production and proton translocation. Acts by coupling the redox reaction via ferredoxin and iron-sulfur (Fe-S) clusters to proton translocation across the membrane thereby conserving the redox energy in a proton gradient.
Subcellular Localization:
Cell membrane.
Sequence:
MSKAEMVANKIKERFPNAEVVVKTNKWGRERVWVRISREEYKELMKFIRELDPEAHYSIGIEQDWGDELGFLNHILLFYDEPPGVSLLIDVHAPKDNPVLPDTSDIFPISLQFEREGMEMVGLDFEGAPDKRRLFLPDDFPEGIYPLRTDEKGVPEEMVKNAGHPYLLRREKK
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MRSLLQIFLTVAASLVAGAAIQKAEAAAGQGIHEEDFNPLCAVSDELKKSEGYAKHLISELDAAASVGINQALRLKIYAETLSTATQRTKLRTLANAYIDYCIAEFTDTVNNCQTALGYTAATNYVAAGVDAVMDLLIGAEAGAAGANGACTRTGDATSSTAKTKSQLNAACTERYKADRPHNPAKKPTAANVRLAPRSGTALTSTNHQTCALTSTQSDCLFHSGHVNTRTIDFLDGLVGLKKDGLKTKAFDPSTAQEATHLALFTEKTALQTLNAIEGKAGAAAGNKSTEQLATLSTLASRAAASQEKKDSEGAELKTQEFGDAGSKINQALWHVVEKLEVAKEALPEASDRKLGSINSFQELTRVTGYYEALKDQQLEKLQKQLTELQETTKKKSKTREQICNEKKDADTCKADKNCKYDETKKEEPQCVLSDKGKQAAKEAESHAEKVGKTTIITGNNCFVIHKAPLLFAFLLL
The following text describes a protein:
Function:
Part of the multicomponent carbazole 1,9a-dioxygenase (CARDO), that converts carbazole (CAR) into 2-aminobiphenyl-2,3-diol. It can use both NAD and NADP as electron donors, but NAD is supposed to be the physiological electron donor.
Sequence:
MYQLKIEGQAPGTCGSGKSLLVSALANGIGFPYECASGGCGVCKFELLEGNVQSMWPDAPGLSSRDREKGNRHLACQCVALSDLRIKVAVQDKYVPTIPISRMEAEVVEVRALTHDLLSVRLRTDGPANFLPGQFCLVEAEQLPGVVRAYSMANLKNPEGIWEFYIKRVPTGRFSPWLFENRKEGARLFLTGPMGTSFFRPGTGRKSLCIGGGAGLSYAAAIARASMRETDKPVKLFYGSRTPRDAVRWIDIDIDEDKLEVVQAVTEDTDSLWQGPTGFIHQVVDAALLETLPEYEIYLAGPPPMVDATVRMLLGKGVPRDQIHFDAFF
The following text describes a protein:
Function:
Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export.
Subcellular Localization:
Nucleus. Note=In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles.
Sequence:
MVTSSVVNTYPLSSYTFGTKEPKMEKDTSVADRLARMKINYMKEGMRTSVEGILLVQEHNHPHILLLQIGNTFCKLPGGRLKPGENEIEGLKRKLSSKLAANSPSLQPDWQIGDCVATWWRPNFETTMYPYCPPHITKAKECKKLYLVHLSEREYFAVPKNLKLLAVPLFELYDNVQRYGPVISTIPQQLSRFQFNMIHQ
The following text describes a protein:
Function:
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSATTKVAVHSLSGNLFIPPNSHAHVLTTQLLDLKNTTDDALPNYLHSLKFRQIHNQTDVRLILGYVAVIIAGALFYFDWKFGWEASKPYTAPAVAAYFVLNGAFSYWLWFVEKGVVYEGEGKTGKVRIATHTKKHIPIYEADITFSLPSSSLSQTIHIRAPMTRWFTADGYFIAKPFQQWLASEVPVIGAADPNNVVEEIGRGSAQGGDFQVNATNAQEILEQLKASGASVSGGAQRRR
The following text describes a protein:
Function:
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity).
Subcellular Localization:
Cytoplasm. Note=Localizes at mid-cell.
Sequence:
MSLKLVEILVLGQVLRLNVPIEQEELLRQAARNLDILVSEMKEKTGLIQLDRVLSIVALNLSFELSQEKNKTAKIEEVLRTGIQQLDHSLENIRVTKEPH
The following text describes a protein:
Function:
Laccase that catalyzes the oxidation of certain aromatic compounds, including L-dopa, to quinones, which then polymerize to melanin. Able to oxidize a wide variety of aromatic diphenol and diamino groups in the ortho, meta, and para positions but not monophenolic groups such as in phenol, tyramine, or tyrosine. Plays an important role in virulence. Plays a role in dissemination to extrapulmonary sites but is not involved in pulmonary growth or in elicitation of cellular immune responses in the lung.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MRGLAKLFFLSCSFVSLVSSEKTDESPTAVSDNYMPKATATIDPSVFALSNDFEITDVPTTREYTFDIANAFASPDGYEREVYVVNNMFPGPVIEANTGDTIIVHVNNHLDEGQSLHWHGLRQLGTAFMDGVPGITQCPIPPGGSFTYNFTVSHQSGTYWWHSHYSNSMADGIWGPLIVHSPNEPLQRGRDYDEDRIVFITDWMHDNSEIIIAALATPEGYKGNIAPPQGDAILINGRGQTNCTATGSSSCFYPPPPEIQVPVNCRVRLRFISATAHPMYRISIDNHPMEVVEADGTAVYGPTVHEISIAPGERYSAIINTNEGKEGDAFWLRTSVALSCMFGAVSQEGLAVVRYTGNGIVSTEEPQTSAWSDLAGVTVPCTGLDQTYTLSPRDSLSAPREPLQSHFFNSERGAFVNVLGNTFQGYGFNNISYQNQIFNPLLSIVQRGGSCENTLVSSRTFPDFGPGNIIINNLDTVIDHPYHLHGNEFQVIGRGTGALSIDNLTNIDFTLDNPVRKDTLWIQGGSWAVLRITADNPGVWALHCHIGWHLTEGKLAVIVVQPSAIGHMESPESWTNLCANTDPNAFGPAKRSSSPSIQSSKTSSFQYLREVKGKVVKRRGAREA
The following text describes a protein:
Function:
Minus end-directed microtubule-dependent motor required for bipolar spindle formation. May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation and structure (By similarity).
Miscellaneous:
MISCELLANEOUS: HeLa cells lacking KIFC1 show multipolar mitotic spindles and a defect in chromosome congression and chromosome alignment during mitosis.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Early endosome. Note=Associated with nucleus during interphase, centrosomes in early and spindle in later mitosis.
Sequence:
MDPQRSPLLEVKGNIELKRPLIKAPSQLPLSGSRLKRRPDQMEDGLEPEKKRTRGLGATTKITTSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATGLKNQKPVPAVPVQKSGTSGVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEERLSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQETVAQAALLTEREERLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK
The following text describes a protein:
Function:
Actin-binding protein that may be involved in the control of cell motility and chemotaxis.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Rapidly assembles at the leading edge of cells in response to chemoattractant.
Sequence:
MSISLKINIVGANTVKTLRFAPDMCIQECCTHIFEKTNEGGPDHGLYQAHIEGKQSARWLAMEKTLQFYDINSDQQLDYKKKHRPQKFKLLDGTIKTQLVDESQNVSEIVNSICKKMGIKNPEEYSLMNSAGAWLNNTQILSEQGISENDITVLMKKFFFNDANIDRNDPVQLHLLFVQCRDGIIEGKYPTQREESLALSALQCQVQLGDYNPTKHEPGFLTLKDYLPLQWLKSKGVEKDIFKEHKKLVSMTEVNAKYRYVQLCRSLKTYGMTSFDVKIREYGKKKMVDHILGITREQMLLMLTETKEVIMTHPLKHIKRWAATDKSFTLDFGDHETEYLILQTPNPEQISQLIGGYIEIIMKARKDSSKVIEKEDTAMGVEEVMAVKKGSVANSSSYMGYGAGGGGANQLQPSQQIPITDLKSALRATDLLIGELGGFRSSTGATPQNFTRSFTTLTPQQFKHQLISHTNAMAIAAQGLFQDMTTPPPTGGIAAFQQAITKRAQIIMAELNTVGTAAKNAGYFPDMASFSDEIIGVATKLSESMARLLAIGSTIQGTDCDEKSQKAAQTEIFNVQSLVTLMMAACDNEYVTDSSSKLLIECAKNVSAAIADMLVVGNSKVEFIDDELLLGQIQNTLKSTSLTSDELLSTTENLASTSCHPESRKQITNITQSALNQSNALLTAFKSGEIPEQDYNLLNARVSDIIESVNLINYAMDCSEREYKISITSNGVEVGEGEILAGTNLTEEFATVANDLTNAIMTMRSNLKNPDTVMESYKMVAGHANRLITCTKAVASRADTQSQQRLFNSTNAVFESVANLSNHCRSYIKNPEQEAHTFQIVETAGHLQFLTQNMSTDAGKIACITSLRDYSKEMIAQVSSLISTSRTSSQYLPDANGITLLKGAKDVSDALSKLMVGIKKVVLDPKSEATQMELLTLAQKQSLPPMNLVSTCKRFAPKISDPNQKQRLIFSSDAAAQSVQKLMKAGEAYKRICGHIEIEEALEVFDSTIADLETTEIAIAGGFLDAVSGTTREGAAELLMVAIKDLNKVNNELVTDIRVNPARLGDLVKSATESASSVAISAKTLICATTGKQVQTKLMGITKQLMIDMEQLIRASRSVRSNPNDRRSELLLDRRSNDVSISTAALVGSTANVDCKELDEASADISNLLSLKMGSLESILSQPTEEFAFYVEEIASSTKALNAASQQVVAMARNKNLKGLGASAKITASALSTLVSHAQNAIVLTENEATKNAILASTVALGGQIIGLLDFSKARIANYKDPIYDQNLINQAKSVEDHLVKVGRSLGGDGNNTICDEAVDRIIEATRSLDKTILPDTSGLQTNAHLEMLHQQSLLAITQASKKLGSITSNLVNSKNNSDLVGSGSTDAERIIEMIEAAKHVVHCSISTYNPDILLPAKSILDASQMLTANQADVNHVLSHAATIAACTQQLLGITRERASQFNEQDEQQVQVRDGIVKSTQQLAHATSSLARAVKSVTSKEPGAKAMISQSLKDLESAINNLLITSSVPASERGIGIADFNKLMSTCRSVSTASSQLIISASSCSQKPKDIELSSILSENAVLMTNSLKDIIKVTSSMMPGVNFCEEAIEIAQRAISDLSSVALSVAVGSFDSSANNKEGLSHVESQERLVDVTKKIGTGINDLLKASRQSPEAIGISAKALSFIAPSLVNTTKPALATAPDADAQNDLVTESKNVGDSILKLCQASLIASSNPSKETYQIIVNKCVDASEAMSKLVAQISSGVNLYKELDESLDRIRKSVVQTSAKDAPKDSENRGYQEYKEELSNLTKNLALSLKTIVATDGNNLVSISTISKDIANYISDIAHVSSAILATTSDQKIRDSIITSSRQVIVSTGDIVNHIKVNSTDKANSSQAKVNDSYRATNDNITRFLQSLKQGAIGEILSDAAIDQIRKVISDLDGYSLFAAAGQLENDQSSQSTMNEVTKQQHLKNLQKDTITQAKLLIVSSSQLVGSSRGTQEHLGSATTKVANTVSSLVKTAKDIASVLADTTSQQDILSASKALSISSQQMVLATKDAQRFKKDATAFRSLGKSAEAVAEAVGQFLTSVYTAISDAGKGIKELEKSIVQVANYHEKPDTVLSNKDATAEIFAQSARDLAKSSIEIVTSYTSSQDSLVKSSQAVVSNVQSFISNSKGVIALLGNGNDDLKSKVLENVKQTTGDMLALLQCVKDQDKNGSTSIADATRSISDRVHSVVTLSKSLPGGQNIVVEEDNVLEDLEALAEDELSACARSIEEATAKLIAARPQSKSKNGKLDAEGVAATIVDASSAIAKAVAKLVNSAAVAQSKRREDQIASGSVYKADPTWSNGLISAAKGVGAATHRLVEAAMKSATGKAEEEELIATARSVAAATALLVSASRAKSGDDYQSQAAHSHLSTAARQVASATSDLVAAAKAATIFDEQQQEEEQEQFNFTGSKVKELEQQMKILKLEKELETARRQMLNSRKQNYNKN
The following text describes a protein:
Function:
Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.
Sequence:
IEASGAGFLLAQQRGYYKDAGLDVTIDTGNGSASAISLVAGGAYDVASADLSTMIEFNTANPQSKLAAVAIQYDLNPNSVMVRKDGAIKKPADLAGKTILGQPFNASRKLFPAFAKAQGFDGSGVKWENVAPDIGDTRFVKGDFDAAAYFFFTGLLNLKARGLTPDQITVFRFSDYGLKSYGNGLIANAKSMQDNPDAMKAFVKATTRGWVDAIADPRAGAAAIKAREPLAHEEIEFERLQLIVDGTMKTAETRANGWGAATPARLQATIDETVAAFGLKSSLAVADIWTDRFLPPAVDRKLKA
The following text describes a protein:
Function:
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Plays an important role in maintenance of endomembrane homeostasis including endocytosis, vacuole formation, and vacuolar acidification processes. Required for development of viable pollen. Might mediate recycling of auxin transporters.
Subcellular Localization:
Endosome membrane; Peripheral membrane protein.
Sequence:
MDKGDCNKGDCNKGDCSRTLCEIVGLLKSWLPWRSEPATVSRDFWMPDQSCRVCYECDCQFTLINRRHHCRLCGRVFCGKCTANSIPLATSDLRAPREEWERIRVCNYCFSQWELGDGGTHLSNIPGISSSSSETSLLSSKTITTANSSTLGSMPGLVGPYQRVKRGSDVSLHGVASKEQGKETSRSNSFIATDVEDPSRFGLNRSDDEYDEYCAYQTDTETSHSPQANKYYGPMEYEEMSPCKHLSFETTADQKSFQKKDENDGRDESEAPSPPDISDDQVAEPVDFENNGLLWVPPDPENEEDERESSLFDEEEDNEGDASGAWGYLRPSTSFGSGEFRSEDRTSEEHKKTMKNVVDGHFRALLAQLLQVDNLPVSDEEGKEGWLEIITSLSWEAANLLKPDMSKSGGMDPGGYVKVKCLASGFRHDSMVVKGVVCKKNVAHRRMKAKIEKARLLILGGALEYQRVSNQFSSFDTLLQQEKEHLKMAVAKIHAERPNILLVEKSVSRFAQEYLLAKDISLVLNIKRPLLDRIARCTGAQIIPSVDHLSSQKLGYCENFRVDRFLEEHGQVGKKAVKTLMYFEGCPRPLGFTILLRGANEEELKKVKHVVRYGVFAAYHLALETSFLADEGASPELPLNSPITVALPDKSTSIERSISTVPGFTVSSIHDKSPTMISGFEPQRANSVPASELLSTTADLSFQKDINPMIPNGSGWQAKETNPGFVFSRCNVSLTLPDRVIEGRNPNMSERDALADTPADKSNPSIEAADILSEGFVRKTYQSSTSVIVEPQDNGSDLTTIQQQNSEDPKEPQSQKEEFPPSPSDHQSILVSLSSRSVWKGTVCERSHLFRIKYYGSFDKPLGRFLRDHLFDQGYRCRSCEMPSEAHVHCYTHRQGSLTISVKKLQDYLLPGEKEGKIWMWHRCLRCPRPNGFPPATLRVVMSDAAWGLSFGKFLELSFSNHAAASRVACCGHSLHRDCLRFYGFGNMVACFRYATIDVHSVYLPPSVLSFNYENQDWIQREIDKVAERAELLFSEVLNAISQIAVKGSRRRIGELEELLQREKAEFEENMQRMLQGEVKEGQPLVDILELYRLRRQLIFQSYMWDHRLINASNLQKLESSDDTKREENEKPPLAKSQTLPEMNAGTNTLLAGSEDNPNPDNLPEHQKESKVAYPVSPALPSKNYENSEDSVSWLGMPFLSFYRSINKNFLLSSQKLDTFGEHSPVYISSFREAELQGGPRLLLPVGINDVVVPVYDDEPTSMIAYALMTPEYQRQISVEGESLVSFPSELNIPRPVDDTIFDPSRSNSSVDESILSMSSSLRLDPLSYTKAFNARVSYGEDGTLGKVKYTVTCYYAKRFEALRGICLPSELEFIRSLSRCKKWGAQGGKSNVFFAKTLDDRFIIKQVTKTELESFIKFAPAYFKYLSESISTKSPTCLAKILGIYQVATKQLKSGKETKMDVLIMENLLFGRTVKRLYDLKGSSRARYNPDSSGSNKVLLDQNLIEAMPTSPIFVGNKAKRLLERAVWNDTAFLALGDVMDYSLLVGVDEEKNELVLGIIDFLRQYTWDKHLESWVKFTGILGGPKNEAPTVISPKQYKRRFRKAMTTYFLMVPDQWSPPDVIANNSRADQPEETSQTGTQAE
The following text describes a protein:
Function:
May be involved in protein-linked oligosaccharide phosphorylation since the deletion reduces the negative charge of the cell surface.
Miscellaneous:
MISCELLANEOUS: Present with 149 molecules/cell in log phase SD medium.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Lipid droplet.
Sequence:
MFVVDWSVQLCMGVISPLFRALVQLPLSIFVWNGFQLVALPINIPLRLFLGTSLSRLVAQTSTLDFYVVLTLFQYFAVLCAFGSIIGLIFGFILGVFHSICGVPSVYISLEWKRWFAPIRTVLERASTSIVNIMRGQTIAPIPMPKPNPTHISKPNMKKFHDEPGADDMTITHDVNCYITPCQTPTNEKIQHYNNDSFNTTTTDDEPTDIWDRSDTYQNSFVTNETLMSLSNRAKLRRNASDADIVNIKILRRNSR