lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the oxidative deamination of D-amino acids with broad substrate specificity. Required to catabolize D-amino acids synthesized endogenously, of gastrointestinal bacterial origin or obtained from the diet, and to use these as nutrients. Regulates the level of D-amino acid neurotransmitters in the brain, such as D-serine, a co-agonist of N-methyl D-aspartate (NMDA) receptors, and may modulate synaptic transmission. Catalyzes the first step of the racemization of D-DOPA to L-DOPA, for possible use in an alternative dopamine biosynthesis pathway. Also catalyzes the first step of the chiral inversion of N(gamma)-nitro-D-arginine methyl ester (D-NNA) to its L-enantiomer L-NNA that acts as a nitric oxide synthase inhibitor. The hydrogen peroxide produced in the reaction provides protection against microbial infection; it contributes to the oxidative killing activity of phagocytic leukocytes and protects against bacterial colonization of the small intestine. Enzyme secreted into the lumen of the intestine may not be catalytically active and could instead be proteolytically cleaved into peptides with antimicrobial activity (By similarity). The hydrogen peroxide produced in the reaction may also play a role in promoting cellular senescence in response to DNA damage (By similarity). Could act as a detoxifying agent which removes D-amino acids accumulated during aging (By similarity).
Subcellular Localization:
Peroxisome matrix. Cytoplasm, cytosol. Presynaptic active zone. Secreted. Note=Transiently present in the cytosol before being delivered to the peroxisomes (By similarity). In the cerebellum, a fraction of protein localizes to the presynaptic active zone, where its activity is regulated by protein BSN (By similarity). Secreted into the lumen of the small intestine (By similarity).
Sequence:
MRVVVIGAGVIGLSTALCIHELYHSALQPLDMTIYADRFTPLTNTDVAAGLWQPYLSDPSNPQEADWSRQTFNHLLSHIHSPSAEKMGLALISGYNLFRKAVPDPSWKDTVLGFRKLTLRELDMFPGYSYGWFNTSLILDGRSYLQWLTKRLTERGVKLFQRKVESFDEVAGGGVDVIVNCTGVWASALQPDPLLQPGRGQIIKVDAPWVKHFIITHDPESGIYKSPYIIPGVFNGTVGGIFKRGDYPEGNASENHSCCQTGCSGPHWRTKDARIVGEWTGFRPVRPQIRLGREQLSAGPSKTEVIHNYGHGGYGLTIHWGCALEAAKLFGKILEEKKSSRMPPSHL
The following text describes a protein:
Function:
Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Sequence:
MEHKEIVIGVDLGSRKICAIVAEFKEGILRIIGTAHQDSKEINSKAIKRGRINSLAHASNAIKEVINSAKKMAGLNADEDRNNPMPHFGEYHPKTKAIVSFSGAYTESIRDVTGVASTKDNVVTIDEINRAINSACAKAGLDNDKHILHALPYRFTLDKQEVNDPLGMSGTRLEVFIHIVYTEKNNIENLEKIMIQSGVEIENIVINSYAASIATLSNDERELGVACVDMGGETCNLTIYSGNSIRYNKYLPVGSHHLTTDLSHMLNTPFPYAEEVKIKYGDLSFEGGEETPSQNVQIPTTGSDGHESHIVPLSEIQTIMRERALETFKIIHRSIQDSGLEEHLGGGVVLTGGMALMKGIKELARTHFTNYPVRLAAPVEKYNIMGMFEDLKDPRFSVVVGLILYKAGGHTNYERDSKGVIRYHESDDYTRTAHQSSPTPHIHSSPTERNLSDLKAPSAPLNTAKNDDFLPIKPTEQKGFFKSFLDKISKFF
The following text describes a protein:
Function:
Structural component of the gap junctions.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MIWEIPIIGDFITKPFKAAKLYEFYDRLHLFTVYLLGFFVLLTGAKQHFGNPIDCMLPKQHDELKSWREYIHNFCLFYGTFRYEVTNGTSSFGSYTADDASVNYYQWVPFFFAFQVCCFLLPFWCWAYMQKMIYIDMAFIVDYAGKINSEKTFEKTKEKVDRLVAYMNDHFRYRRAHKMGYFSWITFNSAFPSVLYSLTKFFFIANVVVQVNLVCKFLDVDSWMWGFDVRNSSKSSWSQHNVHLNSTLSPTNKNSPQSFRWCLQSIPLQESVNKFVNHKAQCIIPMNVINEKIFIGLYFWLLLLTGLSVIGTVKWIFRIRSRKANEVMIFKLIKKVLENEPHDSKMFDYRFNFVHDYLCADGILLIYFMMDTNGFLKTEEVIGALFRKYVSEAGALPPYEATIEDTYQVLLEEPDKAREILILHDTAGVSNYGPVELKKAYIQAADAFVLVYSSADYESFNRVDLLKKWIDRQFGKDKKEVPIVVLANMRDRPATVDSAFANSWAAREKVKLFEVSAKDRQSLVDFIHYVGHRHFHPTKESKFSLSKKLKSEKSSNPAILMDF
The following text describes a protein:
Function:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
Subcellular Localization:
Nucleus.
Sequence:
MAKVPAGEWVPHVEAFVDVSRSPAQHSAGVDALAALVNKDKLTLFDLVSKMDMYLTTTDHIVRSRGILLLGQIMSHISFKRLDVNAMTTLSDFFISRLSDWQALRGALVGCLALLHRKSSVGTIMVADVKRLVEAFIADVQVQSLAAADRKMCFEIFSWILDHYPEAVKTMDDELLYWICQSIDEEKDPECLKLSFHVVEVVMKLFPDPSGFADQFASDLFEILSKYFPVYFTHGAGDNLGVTRDELSRALMHTFCASPYFEPFAIPLLLDKLSSSLPLAKLDSLKYLDNCIHCYGADRMVTHASAIWFKLKEVLFSLSSDQLVSSGSPKDAENKKNQIISEAERCLKTAVTYIHSSDRDIFINLILLDEDIVNNIHSVTTEEKSVGSSLQALGSVVSILAGSSTYLCTRVFQAHFKRLVDILGNSAGFDSQHLSIANGSSPAAINYGALYLSVQMLSSCRAVAVASREGVPAEESWWLILEEKLDQIIHLFGKLLTIDSQPTQSAVRKECVLFAVKGLLILATIPEQCSLPLENAYEDILLMLTLVITSKYENAHLWRLSLKTLTSIGSSAVELHASKREMVYSRIVVDKIICLAESCDASMPLNLRLEACFEVGTASVNYMLRVARSLEETVITNISQVNGSIECADYVTCLIDCYSSRLLPWFFTSGGLNELALSFALRLWDEIGDLVTLDRIRSQGLLDSLMMGMKLLVGVCTEEQQLLIVQKACVFLLNGHIPAAHALASIFNKYLQNSEFSHEIKLDKILDVILGGCFSIVLPSSNLKMSRSSAATSDNADFSDSLPGSIGSKIDILCGLAWIGKGLLMRGDEKVKEISMFLLKCLSSDASLATAAADAFHVMMGDSEVCLNKKFHARIKFLYKQRFFSILMPIFLSKIKETSELTTKLVIYRAFGHIISNAPVSAVITEAHQILLVMVDILAKLSMDNQDKDLVYSLLLVLSGMLMDEKGKECIVENIRIIISVLAQLVSYPHMMVVRETALQCFVAMSSFPHSKVYRMRPQVLQAAIKALDDKKRAVRLEAVRCRQTWQSSFA
The following text describes a protein:
Function:
May be involved in hexitol or pentitol metabolism.
Sequence:
MTFTIDLKDQCIIVTGGNRGIGLAMSQACADAGAAVGIIYNSAKDAEDRASEISKKYGVKCKAYQCDVGQQHKVKEVFKKINEELGPVTGLIANAGVSVVKEALQYNKDDFNKIFDVNVFGVFNCAQAMAQIWTDTGFQRGSVVIISSMSSQICNRPLTQCFYNSSKAAVSNLGKCLAAEWAEKSIRVNMLSPGYVKTDQTSHMDQKLRDFQADGVPLKRFAEPEEMAGQAILLLSPKASYMTGGEYFVDGGNLVW
The following text describes a protein:
Function:
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
Sequence:
MAKTSITVRHQRKKKFEVREYNRCPICGRSRGYLRRFDMCRICFRKLASGAQIPGVVKSSW
The following text describes a protein:
Function:
Contributes to the organization of the actin cytoskeleton and cell shape (By similarity). Plays a role in the formation of lamellipodia and in cell migration (By similarity). Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones, and may play a role in the regulation of neuronal spine density (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). Plays a role in intracellular protein transport and endocytosis, and in modulating the levels of potassium channels present at the cell membrane (By similarity). Plays a role in endocytosis via clathrin-coated pits (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, ruffle. Cell projection, dendrite. Cell projection. Cell membrane. Cell projection, podosome. Cell junction. Cell junction, focal adhesion. Membrane, clathrin-coated pit. Cell projection, dendritic spine. Cytoplasm, cell cortex. Endoplasmic reticulum. Note=Colocalizes transiently with PTK2/FAK1 at focal adhesions (By similarity). Associated with membrane ruffles and lamellipodia. In normal cells, probably in association with the plasma membrane and possibly the endoplasmic reticulum. p80/85 colocalizes with F-actin in peripheral extensions of normal cells and rosettes (podosomes) of src-transformed cells. p80/85 probably associates with components of the cytoskeleton. In response to neuronal activation by glutamate, redistributes from dendritic spines to the dendritic shaft (By similarity).
Domain:
The SH3 motif may mediate binding to the cytoskeleton.
Sequence:
MTVLLLVVLQMWKATAGHSIAVSQDDGADDWETDPDFVNDVSEKEQRWGAKTVKGSGHQEHINIHQLRENVFQEHQTIKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVKGFGGKFGVQTDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGVDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKVQLHESQKDYKSGFGGKFGVQTERQDPSAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNAATFEDIEKPTSTYQKTKPVERVANKTSSIRANLENLAKEKEQEDRRKAEAERAQRMAREKQEQEEARRKLEEQAKAKKQTPPPSPTTQPAEPKTPSSPVYQDAVSYDAESAYKNSSTTYSAEHEPESGYKTTGSDYQEAVSQREAEYEPETVYEVAGAGDHYQAEENTYDEYENELGITAIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ
The following text describes a protein:
Function:
N-epsilon-lysine acetyltransferase that catalyzes acetylation of a large number of proteins. Binds acetyl-CoA.
Sequence:
MVISIRRSRHEEGEELVAIWCRSVDATHDFLSAEYRTELEDLVRSFLPEAPLWVAVNERDQPVGFMLLSGQHMDALFIDPDVRGCGVGRVLVEHALSMAPELTTNVNEQNEQAVGFYKKVGFKVTGRSEVDDLGKPYPLLNLAYVGA
The following text describes a protein:
Function:
Hyaluronidase that mediates hydrolysis of (1->3)-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate. Very specific to hyaluronate: not able to hydrolyze chitin, heparin or chondroitin sulfate.
Sequence:
MKEIAVTIDDKNVIASVSESFHGVAFDASLFSPKGLWSFVDITSPKLFKLLEGLSPGYFRVGGTFANWLFFDLDENNKWKDYWAFKDKTPETATITRRWLFRKQNNLKKETFDDLVKLTKGSKMRLLFDLNAEVRTGYEIGKKMTSTWDSSEAEKLFKYCVSKGYGDNIDWELGNEPDHTSAHNLTEKQVGEDFKALHKVLEKYPTLNKGSLVGPDVGWMGVSYVKGLADGAGDHVTAFTLHQYYFDGNTSDVSTYLDATYFKKLQQLFDKVKDVLKNSPHKDKPLWLGETSSGYNSGTKDVSDRYVSGFLTLDKLGLSAANNVKVVIRQTIYNGYYGLLDKNTLEPNPDYWLMHVHNSLVGNTVFKVDVSDPTNKARVYAQCTKTNSKHTQSRYYKGSLTIFALNVGDEDVTLKIDQYSGKKIYSYILTPEGGQLTSQKVLLNGKELKLVSDQLPELNADESKTSFTLSPKTFGFFVVSDANVEACKK
The following text describes a protein:
Function:
Required for chromosome condensation and partitioning.
Subcellular Localization:
Cytoplasm.
Domain:
Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
Sequence:
MKLIKIQAHGFKSFAEPIQLSFDGGVAGIIGPNGSGKSNINDAIKWVLGEQSSKSLRGDNMEDVIFAGSKNVKEMNKASVTLTFDNSNNASSVPHKVFTITRELERGKGSNIYYINDEIVRYKDIKDIALESGISKSSLAIISQGTVSDIAEASPEDRRGIFEEAAGVSKYKSRKKEALRKLEKTNESLEKIQTVILELEKQLKPLKNQAEKARIYLQKSKELKDVEVGLIIHNLDFYSTKLKEFEIELEGVVETKENLEQQVRKCENIIEQNSGDRLKFEKELHFLVQDLDNLNEKLRNLELISANENQRRELIISGQIKVNPEEKMKVIKEQLQIIKSRINFYTKQTEELSQIVSDKKNEVQELEKTISTKRIEQNKISNKLNETKVKINILLEHKKNKTNMFKGTKTIVEHKNIFKGYHGLVSEVLKVDQEYIPAIDAVLNNALQHIVVEDAQIAVTAVNFLKKNDGGRATFIPLKSIKPKSIKDEHFLALNMKKGFIDVASNLVKYEPKFEVLSKFLLGNILVVSDIESAKDIAAILDNKYMIVTLEGDLIRTGGVITGGVQQASTNLIGLDEQIAKLEEIVPIISKEVENTSNQITNLEHKKYELTNVVSEFSVEAAKVYEKLSNDQKSFDSLTAEYQTISAKDLGESSSSALDQQINEIQAKKVILQAQIRAKKESILSLNTDFSKVTLEKNDLEKSLRILNDSFSKKITEKNKAEFYLDTNQKRLSEFYNMTYEMAKDNFSLSIDITEAEEFVGRIKEEIKDLGNINIDSIKSYEEISERYDGLKATESEIVDAKDKIESAIKEMDKIIITKLRDTLSAINEEFNNVFQSMFGGGEARVEFVDPSDILESGIDIKAQPPGKSIKNLKLFSGGEKSLIAISLLFAILKSKPLPLCILDEVEAALDDANVVRYAEYLQKLKTKTQFLVITHRHGTMSRVDHLFGATMQTRGVTSFFSVELARAKELIKDTKIES
The following text describes a protein:
Function:
Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP). Involved in the import of divalent metals ions such as nickel, cobalt and zinc. Probably responsible for the translocation of the substrate across the membrane. Plays a major role in nickel/cobalt import in zinc-depleted conditions. Contributes to virulence. Required for full urease activity in vitro.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIILKRLLQDKGAVIALGIIVLYVFLGLAAPLVTFYDPNHIDTANKFAGMSFQHLLGTDHLGRDILTRLIYAIRPSLLYVFVALFVSVLIGSILGFLSGYFQGFVDALIMRACDVMLAFPSYVVTLALIALFGMGAENIIMAFILTRWAWFCRVIRTSVMQYTASDHVRFAKTIGMNDMKIIHKHIMPLTLADIAIISSSSMCSMILQISGFSFLGLGVKAPTAEWGMMLNEARKVMFTHPEMMFAPGIAIVIIVMAFNFLSDALQIAIDPRISSKDKLRSVKKGVVQS
The following text describes a protein:
Function:
Mediates the uptake of pyruvate into mitochondria.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MAAVVALCRKAMETVKTKEFRDYLASTHFWGPVANWGLPLAAFRDMRASPDIISGRMTTALIFYSMAFMRFAYRVQPRNLLLMACHGTNIVAQSMQAGRYLNYHYGGGTTAATTAAVSAASATSTGSVDSSATSTGSVDSSATSTGSVDSTAATTPAAEDPVAHSNCQEITCCYLVTWDCD
The following text describes a protein:
Function:
Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group. Catalyzes in vitro the oxidation of various types of cytokinin nucleotides that are known as direct products of cytokinin biosynthesis. Promotes adventitious root initiation downstream of MYC2-dependent jasmonate signaling. Cytokinin degraded by CKX1 is required for cell division in the female gametophyte by modulating the expression of cell cycle genes.
Miscellaneous:
MISCELLANEOUS: The enzymatic activity is significantly greater under acidic conditions in vitro.
Subcellular Localization:
Vacuole.
Sequence:
MGLTSSLRFHRQNNKTFLGIFMILVLSCIPGRTNLCSNHSVSTPKELPSSNPSDIRSSLVSLDLEGYISFDDVHNVAKDFGNRYQLPPLAILHPRSVFDISSMMKHIVHLGSTSNLTVAARGHGHSLQGQALAHQGVVIKMESLRSPDIRIYKGKQPYVDVSGGEIWINILRETLKYGLSPKSWTDYLHLTVGGTLSNAGISGQAFKHGPQINNVYQLEIVTGKGEVVTCSEKRNSELFFSVLGGLGQFGIITRARISLEPAPHMVKWIRVLYSDFSAFSRDQEYLISKEKTFDYVEGFVIINRTDLLNNWRSSFSPNDSTQASRFKSDGKTLYCLEVVKYFNPEEASSMDQETGKLLSELNYIPSTLFSSEVPYIEFLDRVHIAERKLRAKGLWEVPHPWLNLLIPKSSIYQFATEVFNNILTSNNNGPILIYPVNQSKWKKHTSLITPNEDIFYLVAFLPSAVPNSSGKNDLEYLLKQNQRVMNFCAAANLNVKQYLPHYETQKEWKSHFGKRWETFAQRKQAYDPLAILAPGQRIFQKTTGKLSPIQLAKSKATGSPQRYHYASILPKPRTV
The following text describes a protein:
Function:
Positive regulator of proteins involved in permeability. PDR1 and PDR3 jointly control the transcription level of both SNQ2 and PDR5.
Miscellaneous:
MISCELLANEOUS: Present with 1300 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Domain:
The 9aaTAD motif (residues 1054 to 1062) is a transactivation domain present in a large number of yeast and animal transcription factors.
Sequence:
MRGLTPKNGVHIETGPDTESSADSSNFSTGFSGKIRKPRSKVSKACDNCRKRKIKCNGKFPCASCEIYSCECTFSTRQGGARIKNLHKTSLEGTTVQVKEETDSSSTSFSNPQRCTDGPCAVEQPTKFFENFKLGGRSSGDNSGSDGKNDDDVNRNGFYEDDSESQATLTSLQTTLKNLKEMAHLGTHVTSAIESIELQISDLLKRWEPKVRTKELATTKFYPNKSIETQLMKNKYCDVVHLTRYAAWSNNKKDQDTSSQPLIDEIFGLYSPFQFLSLQGIGKCFQNYRSKSKCEIFPRTAKETIYIMLRFFDVCFHHINQGCVSIANPLENYLQKMNLLPSTPSSISSAGSPNTAHTKSHVALVINHLPQPFVRNITGISNSELLSEMNNDISMFGILLKMLDMHKNSYQNFLMEITSNPSVAKNTQSIDVLQEFIHYCQAGEALIALCYSYYNSTLYNYVDFTCDITHLEQLLYFLDLLFWLSEIYGFEKVLNVAVHFVSRVGLSRWEFYVGLDENFAERRRNLWWKAFYFEKTLASKLGYPSNIDDSKINCLLPKNFRDVGFLDNRDFIENVHLVRRSEAFDNMCISDLKYYGELAVLQIVSHFSSSVLFNEKFTSIRNTSKPSVVREKLLFEVLEIFNETEMKYDAIKEQTGKLFDIAFSKDSTELKVSREDKIMASKFVLFYEHHFCRMVNESDNIVARLCVHRRPSILIENLKIYLHKIYKSWTDMNKILLDFDNDYSVYRSFAHYSISCIILVSQAFSVAEFIKVNDVVNMIRVFKRFLDIKIFSENETNEHVFNSQSFKDYTRAFSFLTIVTRIMLLAYGESSSTNLDVISKYIDENAPDLKGIIELVLDTNSCAYRFLLEPVQKSGFHLTVSQMLKNRKFQEPLMSNEDNKQMKHNSGKNLNPDLPSLKTGTSCLLNGIESPQLPFNGRSAPSPVRNNSLPEFAQLPSFRSLSVSDMINPDYAQPTNGQNNTQVQSNKPINAQQQIPTSVQVPFMNTNEINNNNNNNNNNKNNINNINNNNSNNFSATSFNLGTLDEFVNNGDLEDLYSILWSDVYPDS
The following text describes a protein:
Function:
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
Subcellular Localization:
Peroxisome.
Sequence:
MKLKVYADRMSQPSRAVLIFCKVNEIQFDEILISLGKRQQLSPEFKEINPMGKVPAIVDGRLKLFESHAILIYLSSAYASVVDHWYPNDLSKRAKIHSVLDWHHTNLRPGASGYVLNSVLAPALGLPLNPKAAAEAENILTNSLSTLETFWLKGSAKFLLGGKQPSIADLSLVCELMQLQVLDDKDRLRLLSPHKKVEQWIESTRKATMPHSDEVHEVLFRAKDRFQKQREMATASKPGPQSKIIQFSSIGGTSDGPNLVQDTTDRKARRRKWSPPDDVILISAWLNTSKDRKVVVYDEQQAHTFWKRIGAHVSNSASLANLPKREWNHCRQRWRKINDYVCKFVGCYDQALNQRASGQSEDDVFQVAYQLYYNNYMSNFKLEHAWRELRHNKKWCSTYTSENSKGGGSSKRTKLNGGGVYSSSCNPESVPIALDGEEQVMDRPLGVKSSKQKEKKVATKTMLEEREADSRSRLENLWVLDEEEQVMDLPLGVKSSKQKERKVATKTMIEEREAANFRSRLGNLWLLKEKEEREADSRSRLENLWALKEKDIEEQKKLTRMEVLKSLLGRRTGETSEKEETLKNKLIDEML
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
VIIRTVSVPEETRYSEVQSFYEGEVIFITGATGFLGQTLLEKLLRSCPGIRRIYLLIRPNKNESPAERLELLLRSECFKRLNQEYPESLNKVVAVQGNLKEENLGLKSSEYERLTSEVSVVFHSAATIKLNDTLRNAVKINMEGTKSVLDLCHKLKRMKAIVHVSTAFVNSDHDTLEERLYPPTVETDDIITLTKTMDEVDLAKLTPELLGAKPNTYTFTKHLAEWIVAEHGRGLPLVIVRPSIVSASWREPVPGWVDGQQGANLLVASGITGLLTTIVGDKTLFMDIIPVDVVVNALIVAACQAPQRESTSQARFGQIPPVYNCASGTINKILNGEVARLTTKFGRKHVPETLCGRPGLNMTMSRSYQAVAVFVFNYLPALFSDLVRPKKDQKIRMADVVKKYQYFFFTTRFVTTRGMKFSADKFIQLHENNTPLDKEIFNMDIRCINWESYWEDYVKGMRRYLIKQQPRIIPDSPIQKEK
The following text describes a protein:
Function:
Involved in protein precursor import into chloroplasts.
Subcellular Localization:
Plastid, chloroplast inner membrane; Multi-pass membrane protein. Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MASIPLLRFTPTTTPRLLPHPLSLNLLQTRIQTRTRIHTKPTTSISASYNPIPATDRLISAVAYFLPFFNGLQYGRFLFAQYPTLALPFQPILPLLSLYRSLPYASFVTFFALYLGIVRNENLNKYPRFNALQAVVLDVLLVLPMLIQRIFSPGQSGIGLKFTVWMHNGLFVFVVGCFIYGLVSSILGKTPYLPFVTEAANRQM
The following text describes a protein:
Function:
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate. Chitosan is required to anchor melanin to the cell wall, for maintenance of cell wall integrity, and for proper cytokinesis. Plays a major role in synthesizing cell wall chitosan during host infection; chitosan offers an advantage during infection as it is less readily detected than chitin by host immunosurveillance mechanisms.
Subcellular Localization:
Secreted, cell wall. Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MFTFAAFSALLISLAGVVAQTTGTSVDSSILTKTADSTGPSGFSIPALSELTSGAPTDSTVALYSTFAAGATPTVSGAPVLPTSALTIADYPALDVTPPTNSSLVKDWMAKIDLSKVPSYNVTTGDCSTDAAAISDGRCWWTCGGCTRETDIVECPDKNVWGLSYDDGPSPFTPLLIDYLQEKNIKTTFFVVGSRVLSRPEMLQTEYMSGHQISIHTWSHPALTTLTNEEIVAELGWTMKVIKDTLGVTPNTFRPPYGDIDDRVRAIAAQMGLTPVIWTSYTDGSTTVNFDTNDWHISGGTATGASSYETFEKILTEYAPKLDTGFITLEHDIYQQSVDLAVGYILPQVLANGTYQLKSIINCLGKDTSEAYIETSSNQTTTQITAATGSQSTFFQPIVGTATGAEVSAPSEATGSTAAGSAASTTSGSGASASTGAASNTSSSGSGRSATMGGALIALAAVAVGMVYVA
The following text describes a protein:
Function:
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
Miscellaneous:
MISCELLANEOUS: Present with 907 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MDGALINSVLYVSPRNGAHYFVELTEKHLLAFEMLNSMCLLENYDHVLLFLECQFGKSHNLAVIPFDIILVLFTLSTLSEYYKEPILRANDPYNTSRETLSRRALKLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTLTPKKQKWGFDRFRRTKSESGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNTILGNRLLNLKLNEPGEFINMILWTLSNSLQESTPLFLSSHEIWMPLLEILIDLFSCRQDYFIQHEVAQNVSKSLFVQRLSESPLAVFFESLNTRNFANRFSEYVFLNCDYKLPSDNYATPVHPVYNGENTIVDTYIPTIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRLITPRIVADDVIQGISRTLASFNDILQFKKFFMTENLSQESYFIPLLAEGTLSEILKDTQECVVILTLVENLSDGVSFCNEVIGLVKSKCFAFTEQCSQASYEEAVLNIEKCDVCLLVLLRYLLHLIGTEAILDAKEQLEMLHAIEKNDSGRRQWAKALNLGNDPPLLYPIVSQMFGVHDKSVIIE
The following text describes a protein:
Function:
Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression.
Subcellular Localization:
Nucleus. Chromosome.
Domain:
The AWS and SET domains are necessary for transcription repression.
Sequence:
MDWDHNVTFSAVRSLQATTAVAQATDNVVDLDRNRVDSRPGVLPTKNESSPHSSASLPPPSPHPPPPPAFTPSPSPSPSPSPQTATARSSVTDAAPAPKRSPRSPLHSNGSFPPVSDPISSIDSRDALDIDHESTAMLASSSSARKSKPKLQPQLINHLPLAQQAAMATFHEITFNDYHDKKLGRPPGKFDDYMICDCTPNSGNLDMACTDYSGCINRMTQIECSASKCRWGKQCRNQRFHRRQYVDVDIVQTEKKGFGLRACQDIPKETFIYEYVGEVMNQTTFLQRMQQYRIEGIRHFYFMMLQPNEYLDATKKGGKGRFINHSCNPNCAVSKWQVGKHLRMGIFAKRNIQKGEELTFNYNVDRYGNDAQECFCGEPNCVGTLGGKTQTDLSGMDDLFLDALGISDEVEQTEAKGSRRKRGKRLDLDFIPQMRAIQEHEATRVMTAARQAGPKREILEKLLRRMEMTTDVNVQKSLVKLHGFILMQFLLEQWWNDRDIVILIINVLARWPLIARNKVIDCGVEDQVRILAQTYRPRSPEDQKPSLDALRQVKQDDSAADRNDYTQVQPTLAPVRIGAPPAPDAEVSARAEHLLEAWKKLDMTYRIARKDALKPDADDHKDATAVTTWIDRRRMQDLDDPLDLEHAQAPNAVSSELGNALSGDQELREIKPSWQPPPAPPSMPNAPAKRMGGAVHHRSPPGSFTPTRLQSSGQSPLTPDQVTSVLSSSLVKSLSGLVSSLKQQGIQLQQQQQQQPPAQQQPSAQPAAPSAKSIEDIIREANEQEERARKEAEAAAKAARELEVNGGQTSGSSRKRPSSASRHSDKRAKHSSLSSSSQAASKLISSNGSAADSTSKAGSVESVAANERRLRKLVGELVVRQMSKYKDDLERESFKRHAKELTNAIVGKEMRNPKSWPPARGALTELSLDKRAKIKAFAKEYIDKLLARKGKGKGSSTPSNNEGAGSSNNGIV
The following text describes a protein:
Function:
May coordinate the cellular actions of activated EGF receptors and Ral-GTPases.
Subcellular Localization:
Membrane, clathrin-coated pit. Note=Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits.
Sequence:
MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL
The following text describes a protein:
Function:
Part of an energy-coupled inorganic carbon pump.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MLISLSSSTLLTLFFMALSASWLSGLLFLNARIPLRFVHIHIGIAALPSLVSLLALVNNNGDRVVGPWHLDTLAWLMAFFVLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAWLSDDLRLMLICWGATLIGLVLLIGLNKGWKVVSEATKISGYLFTISWIALLSAIIWLFQVTGQWQLTSVLTNENVVLHGTLERTGINLLIILAVMIPAAQWPFQRWLIESAVAPTPVSAIMHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISILIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAIIHLILHGLFKATLFLQAGSSVQRFGVVNQSNEKMSNLWIIVGRVLGLFIAITFWFMTSGEGYQLVSALILGWSLYFSWKQLVVFGEGRMGRIAGVIVLIGFSLIYFTVHNSLYKWLHTDIYQSVQPSAPAVIFVICILLFSSVISTFVTRHQSSTLFAVLYLWLVRVGEARRKSVESHPSYLKHYVSKGGNS
The following text describes a protein:
Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Also functions as a receptor for ergot alkaloid derivatives and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR5A is coupled to G(i)/G(o) G alpha proteins and mediates inhibitory neurotransmission: signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH