lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Adhesion G-protein coupled receptor (aGPCR) for steroid hormones, such as progesterone and 17alpha-hydroxyprogesterone (17OHP). Involved in many biological processes, such as myelination, sprouting angiogenesis, placenta, ear and cartilage development. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG6 is coupled to G(i) G alpha proteins and mediates inhibition of adenylate cyclase. Also able to couple to G(q) G proteins. Involved in myelination of the peripheral nervous system: required for differentiation of promyelinating Schwann cells and for normal myelination of axons. Also acts as a regulator of body length and bone mass. Acts as a regulator of blood-brain barrier formation in the central nervous system vie its association with LRP1 and ITGB1.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MMFDTRGRRCCHWRQKSSTLLFLFALCVACFPLPVWGCGNCRLVLSNPSGTFTSPCYPNDYPNTQSCSWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGLSFNSSVNEMHVSFSSDFSIQKKGFNASYIRVAVSLRNQKVILPQTLDAYQVSVAKSISIPELKAFTLCFEASKVGNEDDDWTAFSYSDKSLTQLLSLEKANNGYFLSISGARCLLNNALPVKEKEDIFTGNFEQLCLVWNNSWGSVGINFKKNYETIPCDLTIGTVVPGDGTLLLGSDRDEIASLKGSVYNFRLWNFTMDPKSLSNLSCSMSGNVIDWHNDFWSISTQALKAENNLSCGSYLIPLPAAELTNCSDLGTLCQDGIMYRISVVIHNDLNHPEVRVQSKVAEWLNATFQNWNYTVYVVNISFHQDLGEDRMKVKRDVMDDDKRLVLWALLVYNATNNVSLNGEMIEQKLSANNASLEDGIRLCKVDVKQLGMCNTLGDPEGFKWTAISPSVYKQPCPNKPGFFMMRTCLCNETSTFWGPIDASNCSRQSNEVANEILDLTGDGQNLTSANINSIVEQVKRIVNKEENIDRTLGSTLMNIFSNILSSSDSNLLESSTEALKTIDELAFKIDLNSTPHVNIETQNLALGVSSLMPGTNAPSNFSIGLPSNNDSYFQMDFENGQADPLASVILPPNLLENLSPEDSILVRRAQFTFFNKTGLFQDVGSQRKILVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHQPICAFWDLNQNKSFGGWNTSGCVAHSDSDAGETICLCNHFTHFGVLMDLPRSASQIDGRNTKVLTFITYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSSALLFLNLIFLLDGWITSFGVAGLCTAVAALLHFFLLATFTWMGLEAIHMYIALVKVFNTYIHRYILKFCIIGWGLPALVVSIILVSRKQNEVYGKESYGKDQDDEFCWIQDPVVFYVSCAGYFGIMFFLNVAMFIVVMVQICGRNGKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNSHSDSTSMDKSLSKLTHAGGEQTSIIPVHQQSLKHPKKISKGKEERKKGRKEERKKERKEERKKERKKEREKERKKGRKEGRKKGRKKGKEKKTKENKKEKKRKESGHSHVMWNSEPYFS
The following text describes a protein:
Function:
Catalyzes the biosynthesis of sphingolipids with very long-chain fatty acid (VLCFA). Required for the formation of plasmodesmal cytoplasmic sleeve during the transition from type I to type II plasmodesmata to modulate post-sieve elements (SE) unloading and symplastic cell-to-cell molecular trafficking at the phloem pole pericycle (PPP)-endodermis interface in roots.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTKGGLGIAAMSYVVIDYMRYVSPVWHSRLMPVLWSVLAIAVVTRVLFYKHWSKELRAAIPFLGSIVFLLCALLFEALCVRSVTAVLGLDWHRETPPLPDTGQWFLLALNESLPGTLVEILRAHIIGLHHFLMLFIMLGFSVVFDSVKAPGLGLGARYIFTMGVGRLLRAITFVSTILPSARPWCASARFNNVPSQPHRWAQKYYVPYANDPAAIRKLLHWDAAYADPGSYIGDYRADWGSMSFLSEFLRPSYSEGSSWFALLKKAGGGCNDLMYSGHMLVAVLTAMAWTEAYGGFSSAMIWLFVAHSAQREIRERHHYTVDCIVAIYVGILLWKMTGFIWSAERKTKQTKLEKIQNSLIHAAKDGDIETVRRLVEEIEVSSRVEKQSKVISNRTMTVFACATVITTLTIVILALTLTSDG
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEPSHRWHVDRGDGHSTEVQAKARVLVPGGSDWPRPDNHGSVGFEDQVIETCPTLPWSHYMQNPLTNDIPMNHIAIEDRPAHPEIYSIALWGPKLHSALTRNRGGRSNAQASAPNSKHLGRQGEEDANDEGSLVLIDAEGVPHTVSRQEAELAGQMQSSEPELLASAPPPRQLYFCPICLRTFLYQSDLERHSITHSESKPYVCRECGKAFKRSSHLQRHKHIHTGERPFSCPVCRKGFRESGELLRHQRVHTGEKPYQCQICRLRFTERNTLRRHAKRKHARETYYQRSVEEGGGSWSTAGDWESEMVSGSGDWGTEDLGNSWNNEASEDFVGEGNQWGDRGPWQ
The following text describes a protein:
Function:
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRMGKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNVKEGVAALRVNGGINLVFGLVGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLCHSQKYLLPAFCPLGLALLFGFSIPDRVMESKQPQFFVEMTQAPLASSRYILADNVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQDKFVKADDFNAWLNQHRQEGIITLVLSIAKDEDISALSLPPADNIDYQGRLVLIQYRPK
The following text describes a protein:
Function:
DNA-dependent ATPase and 5'-3' DNA helicase. Unwinds D-loops, R-loops, forked DNA and G-quadruplex DNA.
Sequence:
MSDIATPAAPSAPVPTQRTLTEPVKAGIREAYAKLQANTPGFATRRAQSQMIGLVSRALATSGGIGVAEAPTGVGKSLGYLTAGVPIALATKKKLVISTGTVALQSQLVERDIPAFLKATGLEATVALAKGRTRYLCTRNAAELEGETSQNGMFEDEQVLYDRPLSPADVDLAKRLAKAYAARTWNGDLDDAPEPVSVPLRMRVTTPASGCAGRRCSYAAQCPVLKARTDVREAQIVVTNHALLLSSLSLGDAENGQPLIAPPSDMLLVLDEGHHIAGVAIDQGAANLPLDDMAKRTGRMQILIAAAYRAVDKDKIGNLLPSEAIEVAARVSKLLKAFHTEVERVWKPEPGERDPLWRAPNGKLPPQWGPAIEELGEETRALFNWVHAAHGTVAKGKQDDAARERLQRSLGMALEMAEQQHNLWSGWRREDKDGQPPMARWITLSRDGDLICHCSPVSAAQVLRTLLWNEVDSVVMTSATLTGGGDFQSFAIDNGLPDHAEMASLASPFDLPNQAELIVPNFPVTPDDREGHPKEVAKYLVRELDWAAKGSIVLFTSRWKMEKVADLLPLAQRNRVLVQGEGNKSQLITEHLRRIAAGEGSVLFGLNSFGEGLDLPGEACTTVVITQVPFAVPTDPQTSTLSEWLESRGHNAFNLIAIPHALRTLTQFAGRLIRSSNDHGRVIILDSRLLTRRYGKRILDALPPFKRVIGR
The following text describes a protein:
Function:
Converts sphingomyelin to ceramide.
Subcellular Localization:
Secreted.
Sequence:
MFPVAICIAFLFLQIQAMPTIITAHPPSEERFSDDWDYKIGHDTVPVLQQFQKNHTLPPVANETARLLWELDQEKSTHLPQFVDQALKLLNLKQVAFEIENSVMSKVSCTACKAGAGLLQHYIKTGKSEKEIKKTIYQFCVNLKIQTPRVCEGITELFAGEVIYVLGKVTIGPDEVCSFVIGDACGDVYNPLHEWEVMFPPVPKPAIVEQKIPEINAPTFKVLHLSDTHYDPYYHEGSNADCSEPLCCRLTNGLASTKEQAAGKWGDYRKCDTPKITVDNMLQHIQETHPDIDYILWTGDLPPHDIWNQTREENLKIIKETVKQMSDMFPGAPIFPALGNHESAPVNSFPPPFIDNPDNSISWLYDELDVQWRKWLPSSVSTTVRRGAFYSVLVRPGFRLISLNTNYCNNKNWWLLLNSTDPATELQWFIYELQSAEFNNEKVHVIGHIPPGHSDCLKVWSRNYYAIVNRYEATITAQFFGHTHFDEFEVFYDHKDLTRANNVAYVGPSVSPYYDLNPGYRIYYVDGDHDKSTRSVIDHESWTMNLREANLYGYPIWFKLYSARQAFGMDALRPSDWDALIDKMTNDPKLFELFYKYYYKASPVRPTCDMSCKKKILCDLHSGRSHDRKNLCQSIESRIDSTANTTWKEWFYNTISVSMSVLWSIPRLTIQLPKYVLGLG
The following text describes a protein:
Function:
Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs. Form complexes with cofactors that confer differential editing activity and selectivity. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MQQHFAVNAFSTRWAPGPSAGDATLRRRIEPWEFEGFFDPRELRKETCLLYEIQWGTSHKTWRNSGKNTTNHVEINFIEKFAAERQYCPSIRCSITWFLSWSPCWECSNAIRGFLSQHPSVTLVIYVARLFWHTDPQNRQGLRDLINSGVTIQIMTVPEYDHCWRNFVNYPPGKEDHWPRYPVLWMKLYALELHCIILNLPPCLKISRRNQHQLTLFRLTLQDCHYQTIPPPILLDMGLIQPLVTWR
The following text describes a protein:
Function:
Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 to establish the pronephric primordium in late gastrulae/early neurulae.
Subcellular Localization:
Nucleus.
Sequence:
MPNSSIRSELTTERGFSGPASNFNIGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLTDGVCDNDTVPSVSSINRIIRTKVQQLFNLPMESCVKSLSPGQTLIPSSTVTPPESPHSDSLGSTYSISGLLGITQPSADGKRKLDDSDQESCRLSIDSQGSVGISRKQLRTEAYGHHPLDALECHFQRQHFPESYSSSTHSKTEQALYTLPLLNISLDDGKSSLTSTNTTIGRNLSTHQGYSALSEFTAFSIKQEASDSSSASSTPSSLCSPTFLDLQPINSGCSAPSFSAFSHPSVYGQFTSHVASGRDVVGATLPGYPPHIPSGQGNYASSAIAGMVAAGGDYSANAYSHGAYAAYGDSWRFPSSSLLGSPYYYSSGTRTAPPPTTAGAYDLM
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTVRMLLLLVVASLSLCGALAQPNVAGLSALRQQSRDRVITLTDEVLSEFIMGRSRPYSAVIYYSAQQVSEGNPSLKLDELRREYAYAAKAFAAGPDADKVFFFEAALEVTQKPFAMLQVNSLPYVVRIPGSQAVAQATLELPKADKMLPENTKGAYPWPAETFVAFVSGRTGAAAAEIDRPSIYKSPFFPPVIFGGVLTAAYLGYKVYALGALRHSAIWAVLSLAVFWFSASGGMYNIIRGMPFFIRDRNGRLQFFLTSRQGQLGAEGFMLGTLYLMVGGSLAFVTYLAPRISSSRIRDSCSLVGALIAASSMYQTFKLWNLKTGYKHVSYF
The following text describes a protein:
Function:
Involved in defense response. Required for NPR1/NH1-mediated resistance to the bacterial blight pathogen Xanthomomas oryzae pv. oryzae (Xoo). Required for pathogenesis-related (PR) genes expression. May be involved in lignin biosynthesis.
Sequence:
MGVLRSTQSMQAEVEEMRAALLHGHGGGAAAAAAAGWRPSAGDADVKRTAGGDGGAAGPRTVCVTGGISFVGFAVVDRLLRHGYTVRLALETQEDLDKLREMEMFGEDGRDGVWTVMANVTDPESLHRAFDGCAGVFHTSAFVDPGGMSGYTKHMASLEAKAAEQVIEACVRTESVRKCVFTSSLLACVWRQNYPHDRRFPTIIDENCWSDESFCRDNKLWFALGKTAAEKTAWRAARGRDLKLVTVCPALVTGPGFRRRNSTASIAYLKGARAMLADGLLATASVETVAEAHVRVYEAMGDNTAGGRYICYDHVVKRPEEFAELERQLGIPRRAAAAAAAQDSGDRPARFDLCRQKLARLMSTRRRCTYDDYYSVAFD
The following text describes a protein:
Function:
[Mature tail spike protein]: Functions as a receptor binding protein (RBP) and probably mediates the attachment to the host capsular exopolysaccharides (Probable). Displays a depolymerase activity that specifically degrades the K35-type polysaccharides of Klebsiella pneumoniae capsule; [Intramolecular chaperone]: The C-terminal chaperone protein mediates homotrimerization and proper folding of the catalytic trimer.
Subcellular Localization:
[Mature tail spike protein]: Virion. Note=Tail appendage.
Sequence:
MINGLIQPKGSVSKETNKNSIALSLGLKFSEVEYLSTEILIDTYIVVFDPISEMVFYVGNAKGNPQTWNLNSDGNLILTTDFSTYTLLKIGLSNPDTSLKIGYQRKKINDSLSSIESVAGYMNSNFVSIMEFQHLITSKPNLNDMETWDWSPALDAAISYVQSYIPQTAVNSQMYGVMPIVFPPGVFQYSTEMKFTKYLNSTGSLSTCYTLIGSGMTSTVLQPITQGQNAFTATQCKINLINIGFRSGASYQTGAVLGSSTAWLPVVHSNWRCVGFSGFARGVVANLLFDSTFEDIFIQNISNMQSTSDVSYGFTFEVYTGPANGGTTGDGSGDDSNQITFIRPTIETSNADNAILFNASSINSTYPHHAINVFGGHIETHNLKAKCYNLKNCFNVNFYGTIFSQNGSAVDTNYRLGYIEACYNINFKNCRQVTTNRLTAYSSTDVKSIKITGNSKNIIFDNNHFINPYYSLNTYNKGPSYNIDSDTATVLDDSYLVINCTFNTYTNRNITSKISISNKNICNKNHILTVNDNGELVVSYTTSTDYSVTPTDILSFTNTGQIKTNGSIQLGIYNGTAGSKSIDFYSNGDKTTSMARILVDSSGRLYIRSFNGSQEWVFGSNAITPTTTSVYSIGSPSLTVNNLYVQNPVTVVSDENYKSNIQKIPDELLDAWENVEFNMWKMKAAINVKGITDARWHVGYIAQKIKSVLENAGLNWQDYGLITYESWIESEETYDQNGNVLSPYKAEGEIYMLRMEECLAVEMAYQRRKLDRIEKQLQK
The following text describes a protein:
Function:
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source (By similarity). Because of its role in energy metabolism, involved in the modulation of aged-related cardiac function, mobility, and lifespan.
Sequence:
MGRKVTVAVSTLNQWALDFEGNMVRILQSILEAKDMGASYRTGPELEVCGYSCEDHFREPDTFLHSWEVLLEVMMSPMCENMLVDVGMPVMHRNVAYNCRVAFFNRQILLIRPKMAMCDDGNYRESRWFTAWTKALQTEEYVLPRMIAQHTGQQTVPFGDAVIATRDTCLGYEICEELWNVRSKHIEMSLAGVELIVNSSGSYMELRKAHITSDLIRNASFKAGGAYLFSNLRGCDGQRVYFNGCSAIALNGEILARSQQFALQDVEVTLATIDLEEIRAYRVSLRSRCTAAASAAEYPRIHCDFEMSTHSDIFKTSTPPLNWPMHTPEEEIALGPACWLWDYLRRSGQGGFFLPLSGGVDSSSSATIVHSMCRQIVQAVQQGDAQVLHDIRQLLADSDYTPDNAAGLCNRLLVTCYMGSVNSSKETRRRAAQLANQLGSYHIEISIDSAVNALLSIFNAVTGLTPRFRTQGGCARQNLALQNMQSRIRMVLAYIFAQLTLWVRNRPGGLLVLGSANVDESLRGYLTKYDCSSADINPIGGISKMDLRRFLTYAKDKFNLPVLESIIDAPPTAELEPLQENGELQQTDEADMGMTYAELSQFGRLRKQSFCGPYSMFCHLVATWKSDLSPKEVAEKVKHFFLCYAINRHKMTVLTPSVHAESYSPDDNRFDHRPFLYRPNWSWQFKAIDDEAEKLQPIYTPSSAQLRPSSEDLLISTQRSSHLDDSKHSSPLSSASASASIDVGISTAAVPLPGAAAPGGLSKKPSGYSKVHVNVLGKIKDRTGIPV
The following text describes a protein:
Function:
May play a role in transcription regulation.
Subcellular Localization:
Cytoplasm. Golgi apparatus. Nucleus.
Sequence:
METSKNPSDLPKKPANVKKNRRRFQKSQKKSISPSSGSELPNFKTTISQNNEEVKTSLKEDSSKFHPSASAPIFVPTSSVQLNVSKNNGHKASDIVDAVSSKDEELRKHAKGEGKRSKNRKRSSKHSEKQAVDLKSSNSSQETSSSKGSVNNKSERSREAKSRMPKNSKEIKKGLDLSKLDMTSRMIVELKNRLYECSVCTDTINPSTSIWSCGTCYHVFHLSCIRKWCKNSIEQRNEDAWRCPYCQSNQTETSLHYLCWCGKQEKPEFVKNLVPHSCGDPCGKTRGQDCEHPCPLLCHPGPCPPCTATVEKFCLCGKESIHARCSNISKVNTEPFRCENVCDELLPCGEHTCKKRCHSGLCGACFEPINAKCYCGLHSKTYPCSSLPSPSISKKDENGSVKEWFGYYSCNNPCTLFFDCGLHKCSKTCHPISETRAHCPFATDVLTKCPCGKEDISFLLKGHERKSCSDPIPTCENICGKLLSCGHRCKYKCHLGSCGTCSETLTIPCRCTANEVQVTCEQLQNGFIPTCERLCTILLSCGRHQCNKKCCSGYSKAQTRLARRPKGAKLRYHLLTEEFEEEHICFRPCNKKLSCGNHFCQHMCHRGPCPRCLEASFEELPCTCGRTRLYPPVACGTPIPDCPYLCVLPKSCHHPQVKHNCHPTSEPCPPCPYFVKKRCLCGKHILENQPCYRENVRCGELCNKLLSCKTHFCEKLCHPDGECESSCKKECGKRRMYCEHVCQSPCHAGHPCDERIPCKAPLEVSCECGRIRKKVTCDASYDNPDPQHKVSCTLECSQQQRNKLFAEALNIKTDRRSNDVAQYTKSLLVFYGKHSDFADEVESLLRNFVNNKASSFRFPSMRREQRAFVHMFAKLLGLESVSFDPEPKRNVMVYNKGEAKLPNMLLKEANLYHLQHPEIPLKPDSLLGPEEENATASHIDGSSNASDSGYNAFVLKELLKEVNDESAIFSVLDDIVDFNHLTWSILFGENYIILKPLNTDLIVNKTGKLVALRPLVNRRLADAGIASRCEICEINDKNEIVKTRSQRIHSKKKAFLSLVPDKSIGVINRYKELATEL
The following text describes a protein:
Function:
Involved in vacuolar protein sorting.
Miscellaneous:
MISCELLANEOUS: Present with 623 molecules/cell in log phase SD medium.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MRISKNSHKRQRTRLYFLVTFIIYSIIPCRAVLVPWLDDDPFEATLLEMGDEPWSKDILSSTPPLHPSEVTEDNKSLKQRGNVPQYVIDNSPLLHLYSEEKYWPADVKDFVKRFQLRDHSGEKIINEHLRDLSDLQEYYSVELENGTWGRVSSEGTYMTSLDDFDKGPDWLLGEQPEYGTGHIKKAPAVLFVVDKGNGWVDAFWFYFYPFNWGPYIMGSGPWGNHVGDWEHSLVRFYKGEPQYLWMSAHGGGSAYKFEAIEKIKRLRRVDGKLTNEVIKKPLIFSARGTHAHYASVGQHAHDVPFFFMPLSDFTDRGPLWDPSLNYYAYTVTVGEKMTPCGAEETKMGLEWLSFKGAWGDKQLRPRDPRQKWCPFQWKYIDGPKGPLFKNMERVSLCQRFKWWNFWKGCPARRYIKRGEGLDAEKNDLVGDNCGILLYNIRPKWLRSILRFLTWRGSVCFIMDYFTG
The following text describes a protein:
Function:
Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPQNEHIELHRKRHGRRLDYEERQRKKLARAAHDRSQMAKTLRGHKAKLYHKKRYSEKVEMRKLLKQHEEKEQKNTVEQPDKGAVPAYLLDRQQQTSGTVLSNMIKQKRKQKAGKFNVPIPQVRAVSDAEAFKVVKTGKTNRKGWKRMVTKVTFVGESFTRKPAKFERFIRPMGLRFKKAHVTHPELQTTFHLPIVGVKKNPSSQMYTSLGVITKGTIIEVNVSELGMVTQGGKVVWGKFAQVTNNPENDGCINAVLLI
The following text describes a protein:
Function:
Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.
Subcellular Localization:
Photoreceptor inner segment membrane; Single-pass type I membrane protein. Photoreceptor outer segment membrane; Single-pass type I membrane protein. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.
Sequence:
MSVFVYFLSFCIFIHHHQFCLCFHSVAQTYLSLEEIQEPKSTVSFLQTDSESTDSSLSAKKKQPLDSRETERHWLLRRKRSTLFPNGVKTCPDESVTEAVANHVKYFKVRVCQEAVWEAFRTFWDRLPGREEYHYWMNLCEDGITTIFEMGTHFSQSVEHRSLIMQKLTYAKETVSGSELSSPVPVGDMSTLGDAGLSVPYPGVTSYEGISESSLERPEDSISNEIENVVEESTKTAAEQVAEFSIHLLGEQYNEELQDPSSFHHQRLVEDFISEVENAFTGLPGYKDIRVLDFRSPKENGSGIDVHYAVTFNGEAISNTTWDLISLHSNKVENHGLVELDDKPTAVYTISNFRDYIAETLHQNFLLGSSSLNPDPDSLQLINVRGVLLPQSEDQVWNTQSSSLQQALPSILDNTPQAEWPSADESTTSSISPLGFSSGLPSATGRELWSESPLGDLVSTPKLAFPSKVSLSSSPEVLDVSGLTLHSVTPAVLQTDLPVASEERTSGSHSLEDGLMKVEVSEDFLSINPLPSSPFTYPVPKETPPSMEDSGVSLPSSPYPVSSVTFDLLAKEVTTPFGMDSLASKVKDQLEVSSWMPDTTMEKEFMFESGLGSGSGQKIDLITWPWSETSLEKSTEPLSKSWLEVEDSLLLTEGIDVKPVIDDKIDSADQRAEHSEYGPFDGSTNFAEDEPLGGPTVSLFAETTTQSASPVLPKHTSEVPDIDYYSVTKSPPLLTFVAVSASIDKADQVEHFLKEDMEQTTESFNHEWFDSKISIEKSDVQPLRTTVPESDVFWARTSPLGKLSRDTLASTPQSTDKLWLKASMTQSTKLPSTISSTLLEDEVIMGVQDISLELDQIGTDYYQPELIPEESGMVGSYVEMSTNIHSTEMAVVAQPTRSDDLSHTQAVGAVVVFFSLRVTNMMFSEDLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIVVNSRMKFTRSVLPNVTNAVYVILEDFCTTAYQTMNLAIDKYSLDVESGDQANPCKFQACNEFSECLVNPWSGEAECRCYPGYLSVEDLPCQSLCDLQPNFCLNDGKCDIMPGHGAICRCRVGENWWYRGEHCEEFVSEPLVIGVTIASMIGLVLISSAVVFFIIKALQAQYVRRERERPSSRQRDGLSSVERAVKHNPVFESYEADLEQYEGPYPQRPFYSSTDREMIAGLSREEIRQMYENSDLSREQGRALIKTHICN
The following text describes a protein:
Function:
Putative pheromone receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFSIGEILGIAYLLQTIIGVLGNFYLIYHYCFHFEIQKSPRRIHLIFIQLSFANAMFLLCRGIPMTIFSWGWKFFLNDVVCKIITYLQRVFRGLSICSTSLLSVFQAVVISPSSTKWAILKVKLHKSMAPCCILCWILNLLIDAALLVYITGPRNITKSKWKNKIRYCFMDTYNMDRLKLQYLNAFYDFIIVAAMTVSSAYMVFVLYQHRQQVQHIHSTKVYLRASPEIRAIKVILLLVSIFFFFNSACAIIAIYTDYFKAYAPWQFYVPMFLSMSFQAICPFVLIGSETWSLWKFCCSIQRIKCSCVIPLSIVSRQIHMEPPK
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MKNFKAKIITAKQNVMEKTAKRENTLEPDEMKELEKKTTETKDFLRKLTKSVEKETLSSGVSIQDGTELADNFLDYSVHVRDNQSDLVILSGILSKIGEFQAGFEDLKSKLNSSLINDVSDPLKSIIKTELKQAKESKREYDRVRVAFDAHLSELANLRKQKNVKPPKIQESEEECERLRTNFERVGIDTTCLLRDTNVITEFETVEKLCDYLDSYHTFFQKGYRWLAQMIPDIYEYRLYVEKRKAELEKSKVRISMMVSPQKQQADSLSKTKCFGEDLSVLLNREGSTLPWFIVRAFQAIRNHIATEEGLFRLSGTKRIIYEYKQKIDEGKEYNLSEILDIHVVCNLVKLYLRELQPEPLLTYSRYNELIDTCNIEDQNQRVDKISKILSSLPKHYYTLLHHLIHLLSQIASQPKSKMGPANLATVIGPNILICQTDVVLEDIALGNMVVTTIIQNFDRIFGGPPLLQQSVPDTYVPPPNNTRNNSVNNFNNVQPSSFSASTSRSINLNKSTNNPNINDDNNNNNNINNSDDEPYDPNAPPIYSGVPMRGNIKHSDSCSTLGDSFDEGDAVELSD
The following text describes a protein:
Function:
Involved in plant defense. Required for basal resistance against P.syringae pv. tomato DC3000.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MKPPSLPLLLLLLHLSATISAAPSLSPTPSPTTSPIPPHKPSSSSSPLDPKQLKALESLNIPTVKDPCNHRPTTKSTSSSVVTCDTSSPFRLVTSISFTNCSTDLSISTTALRALSPSLTSLSFLNCPSLSPPPRLPDSLHSFTAVSSFLRRRNGLSGVFLARLVNLTDLTVSSVPVSTSGLFVILGNMHEIVSLTISHANLSGNIPKSFHSNLTFIDLSDNLLKGSIPTSITLLSNLKSLNLSKNTISGDIPDSIGDLISLKNLSLSSNKLSGPIPDSISSIPELTHLDLSGNQLNGTIPRFISKMKYLTHLNLANNAFHGVLPFNASFIKNLEVFKIGGNSDLCYNHSVLSSKMKLGIAQCDKHGLPLSPPPQKEDSNSDYDYGNEDDTSEKKKEEHHGPNKVVLGVAIGLSSLVFLIIFMILLAKWCG
The following text describes a protein:
Function:
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.
Sequence:
MADSATELAEQPPLCKTNGTNNPTPEQLVAKAIAPVKAEFLRPPPPSRTNQNDTVIPNSDAKAASQSIVSKEKKSKRQLKRERREEKKSALNLCPELAKTEDVNSCRYGDKCRFSHDLEAFKAQKPDDIEGKCPFINGEGKACPYGLACRFYSTHENGVKGDASNTRKQSSEVNGLNKDVQKLLWKNRFKFPKADAILKSLGLMGPSNSRVKRQNDDEVDNASVNDSHAASENGCGKLATDAADKLECPSEVLTEDNADAVTDEIRPLKKAKSDVDEKCCSGEEANGASVPEKDSEDSFKETESDAVNNGALTEPDGSLKTHPREKKLIDFKGKLYLAPLTTVGNLPFRRLCKLLGADITCGEMAMCTNLLQGQASEWALLRRHSSEDLFGVQICGAYSDTVARTVELIDQECTVDFIDINMGCPIDIVVSKGAGSCLLTKPMRMKSIIHAASSTVDTPITVKVRTGYFEGKNRIDSLIADISNWGTNAVTIHGRSRQQRYSKLADWEYIYHCAKKAPESFQVLGNGDIFSYTDWNKHKSDCPELSSCMIARGALIKPWLFTEIKEQRHWDIRSGERLDILKDYVHFGLEHWGSDTKGIETTRHFLLEWLSYTCRYIPVGLLDVIPQRINWRPPSYYGRDDLETLMASDSAADWIRISEMLLGKVPEGFTFAPKHKSNAYDRAENG
The following text describes a protein:
Function:
May act as a growth factor in the germinal layer of the epidermis. May also be involved in growth of regenerating glands and in protection of the skin from the external environment.
Subcellular Localization:
Secreted.
Sequence:
MNHKLFCVHFLLLILSVCYIQGQDAGGEPAPAEGVAPAPAEGGAPAPAPAEGEAPAPAEGGAPAPAPAEGAEPAPADGGAPAPAPAEGGAPAPAPAEGGAPAPAPAEGGAPAPAEGGAPAPAPAEGEAPAPAPAEGEAPAPAPAEGEAPAPAEGEAPAPAPAEVEAPAPAPAEGEAPAPAPAEGEAPAPAPAEGEAPAPAPAEGEAPAPAPAPAEGEAPAPAPAEGEAPAPAPAEGEAPAPAPAEGEAPAPAPAEGEAPAPAPAEGEAPAPAPAEGEAPAPAPAEGEAPAPAEGEAPAPAPAEGEAPAPAPAEGGAPSPAEGGAPAAAPAEGGAPAPAPAPVEVGPKTEDCKGDPFKRTDCGYPGITEGQCKAKGCCFDSSIVGVKWCFFPRTARAQCLFSPGDREDCGYSSITPMECMKRGCCFDASITGVKWCFHQK
The following text describes a protein:
Function:
The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity. Elba2 can act as a transcriptional repressor and binds the palindromic sequence 5'-CCAATTGG-3' to mediate transcriptional repression.
Subcellular Localization:
Nucleus.
Domain:
The BEN domain mediates DNA-binding.
Sequence:
MAGGFRPYDQDSCPNLTNSEAPEFSMSVVCKTEPHYFHPQTAILPSVQYSHPYHHYLSQFAPNFVPYYYRLLSRPIMKQEEMDIENYINYEVAAQQTMMRQRTLKPLGQLQIQMPPPIIVNQPVKPVPVKAVPVRRSSPPKRRVINAQLVAVATASGGIKNIEPRVEPLPRLEESFKQQVAKIQKSQHHYEQLFGRLTSMLKTLNQRYDNDAEDVPAPPSKRPRHMSTSSSESHIPDTASEKDEKDTLVQYPHRVQKEDGSAVYVLGPNGTQITAHQYGEVFWTNAPVATRCLLCVVFSSDELATHTLTGKPSPAFYGRERPPKLQLDQRKVDDIVVCVRNRTGGKERVIRATITTKCADTAKKYKRRAKKAQKVAIKEEY
The following text describes a protein:
Function:
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGEGGEAELERLQAEAQQLLKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEQAEEESEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKDRVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDAKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKSSEAKEGEEAGPGDPLLEAASKSGDEKDVSA
The following text describes a protein:
Function:
Acts as a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
Subcellular Localization:
Nucleus.
Sequence:
MFTSQPSSVTLTKMLRTNSKLKDANEDGEDDPRVVFPAIKSDDDLILREIRRRKKLAALDAASGRPAEPEDRLGNKKLITSKMEFLEPEEHISDKILFIINNLAFNNLETKLTEMSSQIKPEHYNWFAKYLVNHRVSIEPNNHSLYLQFLDKLALPHMYKKINNETLIKCVIMLNSEQTLKSGTDRTILKNLASWLGSLTLAKNLPIKHHNIAFKDLLLQGFRSNRLIVAIPFVCKVLEQSSKSKVFRPPNPWLMGILKLLIELYHYGELKLNLKFEIEVLCKALEVELKDVKPTEMLKKQEELSQQRQEVEEVKAAARSLAAAQQQAEQQHSHLSIENVIGRATGTLNPNSVPSAGTSITATQPLENAGPNNLPAGSHSLSLNGQAGYASSLQDLLKQALLELPLLMTFSTEVVLNNNILWKRVVFTSIERAIRDIIGPVVERSVTIANISTREMILKDFAMEGKEDQMRTSAHMMVKNLAGSLALVTTKEPLRNQILVNIRSLSIQNGFPEHNVSDEEIQQVTADNLDVACQVIEKVATDKAILEIDNSLASAYEARRRHREHTNSAFWDTSAMAASHYSGMLPNPLKLKLGGLEPEQLRIYEEFSNVRDDSNPSNAMAVQQQQHSWQSQQQQQQQQQQQQQQQQQHQQLQLQHQQQQQQQHLQQQLQPQGPVPGLDAARSPALAESTPNLLVGPTENANRPLNSLSEALTRINSLAGEIERLVLTVTVESLAEIGENHEIRGLITEILKMLRQANPTLKDQLTLSFAQKSVAMLYRSESKLGRDLFVNLLEEICEMTPKVAHEVSQWLIYAEDERKYNVPVTLVLITHQIVSLGDFDAQSAKLILRDYKPSLMNYVAEFIEACVMGSESSLIPIGLLKHSIQALQRAIQIGRATPKVTSIMQNIQDKLPALGSAKDLGPVTIKSINDEAGLREQLSFCFAEWVRMYSSSYSVEKPFIEFISSLQAHGILKGEEVSSLFFRVCMEVSIDAYIKAKASGSTAARGIFQPVDAFARLISLMIKYHTDPTGIDIERAKTHYMSKLLSIVLMVMGQFHKELGEHFQQKPFFRFFSGLLVHINALETHLGSCYQSVMMTLSNLIESMQPSNFPGFTTSWMALISHRLLMPKLLMFKDREGWSTVHRLLLGHLRFLRPFLASGTLDDVGRTLYTGTVRIFLVLLHDFPTFLSVYHHSLCSALPPHCIQLSNLILAAFPLGVRLHDPFVPGFNLESLPDSRISPTIISDFTHVLEQADLRQLVDKATSAASPQIAVGPIKDRLTHPTKATEGTVYDIPLLNSLVLYLGVQAILRVERESVPLYDSSCTSATIYKQLVNEIDPEGRYLLLVAAIQQLRWTNSHTLWFSSLLIDTFMSSDSEVVKEQVARVFLERLLVQRPHPFGMIYAFIKFLSQCGTTTTANTNSNLNHGNHHIGNGNGNGNTLAMEKAGDAEGLGSSLESLKVVKKSQELMALFAICRKHVVQIN