lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for chromosome segregation, the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores and spindle pole separation. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC80 complex to microtubules. The recruitment of spdl-1 to kinetochores relieves this inhibition. Required for embryonic development.
Subcellular Localization:
Cytoplasm, cell cortex. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the kinetochore during nuclear envelope breakdown and remains there until the metaphase-anaphase transition. Localizes to kinetochores, spindle-associated rod-shaped structures and near the cell cortex in a knl-1-dependent manner in anaphase.
Sequence:
MSIKLEDLHSFNEAVLFKGEEDEAPAPVLLLDKYRVRLVPITELPLVSNYSNTSQLGLNSEEVLVIDSPIESAEKQKTSSLLNRRENKKTIKSEKEDESMDMETAEGDKENTVSETGGGPLVTSFLTLDKLEKDGVNDVEIVGLDCEIQFFDANPIPFEDGISLQRFLRLESSKNFSAAVDKLPIWISTIGHHFPSVCWLAAGRTNKNVQVSGATRILGYFNENSQKLVKQLNEACGAAQVNRYRAVYDVIRKIATPTREAPGEVIIDMRWNTKSSLVLLEQPDNAADCTIKIDLGWGDNRFFIDETIFEQLFFVLNLADVLANPEKEVVFRSESDKFDDLVQEMKQLVEACSHEDNVFASNEKSEQVTDKVWNIVRKCSDVKQATMLFKNFLQALTYGKIKSHVQEGNKSHLASLIRASKTCDFRMPILERLSTIEMMMEIGVESLRGRIINKFSDTLQFPSDELTFILKTCENDLSTLEGTLHSSVVSLLPITMAMATIHQIFGFLNVKDLVVLPDLARRVLTKYTTGMVEKAKRGETETDYVFETTLPLLRMNKEAFMHKRPRIWTCENTNTVGANVQTRAMTTLELEPSLEHVCRLVNASRPVRPIDEDNRKPTEEERNADYTVSHTIFSYLPKL
The following text describes a protein:
Function:
Polarity-determining protein which forms a conjugate with the ubiquitin-like modifier HUB1. Involved in bud site selection and cellular morphogenesis during conjugation. Required for pseudohyphal growth.
Miscellaneous:
MISCELLANEOUS: Present with 672 molecules/cell in log phase SD medium.
Subcellular Localization:
Bud tip. Bud neck. Cytoplasm, cytoskeleton. Note=Sites of polarized growth as bud tip, bud neck and mating projection. Hub1 is necessary for the proper location to mating projections after pheromone alpha treatment.
Sequence:
MISSELTNDQIIDLISDYKNFKRIIEASVPEDDRRRNQNRQNRNKDLTKLSNVQFWQLTTDVNDELMKRLTDSGADASLNDLDLKRGKAQSKLSRLKDAKFHKLILDIFTEIERRNLHHLDMGTHNNGLDEGDLNFYLNDTLFESFKINDDFMSVNGIISIEVFRELKTQFTLYFQNTLHRIDPVDTTTTRLPILLETIIKIAKLIGDLLPVLSSVSLQSSLENEIVYLKSALSHAITSTRYFLTYGDLIPRIVAQSSISEVIFAFCNIAQIVKIKSTSRDDISRNEGELSDIEAGMKPLKIIEKVKNEKNGKDISSLGDSGSTAVSFPSSGKPITKKSDMPVVVASPSISIIEKSESSIRESGKVRNNTSGETNLASVSPLKNTKNSSRITSEPSPREGLPLKVVSNSRSPSPQGNTLPLIGKFRQDYQASPPKKVITKPVAETAKPYANIPPAADVLYSPTVTKMRKFREKVQKFAPNSGLGLRISTSEENLNNSDVNSTTHNANINNLVEFVESKSMVVLPMAQGILNDVQASKSKLFKSARSVSRLCQNSIEIIPILESVIDMTTKAMVQKSFKLDLGEHCKEIIERLTDCSQKLSELCTYGCDSTKLGKKRFYQKLADILMEVTKRTRELVECVKMANRQTLSQDLSSFFNYRSVQ
The following text describes a protein:
Function:
Negative regulator of sexual differentiation. Acts by repressing the transcription of meiosis-inducing, ste11-regulated genes until cells reach a critical level of starvation. RNA-binding protein that preferentially binds poly(U).
Sequence:
MSSSSPSSQSRLSVPGRTPHLPPLTIPHTVSAEGLATPNTPHALLPTGLLMGSPFVQSPTSYTSMHGLPFSTTQMAAAPAHPTTGYNVSRVTSPNVANFAPGYFPLPNNTTQPVKTVYVGNLPPNTPIDEILSCVRTGPIESAWILPEKNCAFISFLDPSHATAFFQDAALKRLTIRGTEVKVGWGKNSASNSSVLLAVQQSGACRNVFLGNLPNGITEDEIREDLEPFGPIDQIKIVTERNIAFVHFLNIAAAIKAVQELPLNPKWSKRRIYYGRDRCAVGLKQPAYFSKGQVGVVGGYPVMGYPPPSPVLQKPDLIMTGNRTVYIGNIHADTTIEEICNAVRGGLLHNIRYLQEKHICFVTFVDPVSAFRFFEMSNIHGLVIRNRRLKIGWGKHSGPLPSNIALAVAGGASRNIYIGNADDSLTIERLKEDFEEFGEIEYVNFFREKNCAFVNFTSLASAINAIDRIKQKKGYENYRISYGKDRCGNPPRTNSKSDVLSVSSDMSMPVDLVVPQQGISGFMPTNSNI
The following text describes a protein:
Function:
Non-functional DHOase.
Sequence:
MTISIRGARVIDPASDLDQVGDLHIEAGKIVAIGAAPAGFSAQKTLDGAGLVAAPGLVDLSVALREPGYGRKGNVESETRAAAAGGTTSLCCPPYTRPVLDTPAVAELILDRAREAGNAKVYPIGALTRGFGGEQLSELVALRDTGCVAFTNGLHGFASNRILRRALEYAATFDLTVIFTSQDTDLAEGGLAHEGPTASFLGLAGIPETAETVALARNLLLVEQSGVRAHFSQLTSARGIELVAQAQARGLPVTCDVALYQLILTDEALVGFSSLYHVQPPLRTRADREALREAVKNGVVQAIASHHQPHEADAKNAPFAATEPGISGAELLLPLAMTLVQDGLLDLPTLLARLSHGPAQALRLPAGRLAVGQAADLVLFDPQGSTLAGESWYSKGQNSPFVGHCLPGRVRYTLVDGHLTHEG
The following text describes a protein:
Function:
PUMPS are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. This leads to a decrease in the efficiency of oxidative phosphorylation and an increase in heat production. May be involved in protecting plant cells against oxidative stress damage (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MADFKPRIEISFLETFICSAFAACFAELCTIPLDTAKVRLQLQRKIPTGDGENLPKYRGSIGTLATIAREEGISGLWKGVIAGLHRQCIYGGLRIGLYEPVKTLLVGSDFIGDIPLYQKILAALLTGAIAIIVANPTDLVKVRLQSEGKLPAGVPRRYAGAVDAYFTIVKLEGVSALWTGLGPNIARNAIVNAAELASYDQIKETIMKIPFFRDSVLTHLLAGLAAGFFAVCIGSPIDVVKSRMMGDSTYRNTVDCFIKTMKTEGIMAFYKGFLPNFTRLGTWNAIMFLTLEQVKKVFLREVLYD
The following text describes a protein:
Function:
Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. Capable of producing kinin potentiating peptides.
Sequence:
MAPSGPLLRLLLLGLLAGAPAAASLLRARGCRRPLRADQLSGLGRRWAALGARTVGPRAGPASLTSRGKARNALGRSLRPAAAGPRLGPRGRCGAAWGLLLPASLSSWGTYPRPHEYLSPSDLPKSWDWRNVNGVNYASATRNQHIPQYCGSCWAHGSTSAMADRINIKRKGAWPSTLLSVQHVLDCANAGSCEGGNDLPVWSYAHEHGIPDETCNNYQAKDQECNKFNQCGTCTEFKECHAIQNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATEKMVNYTGGIHAEYQEQAYINHVISVVGWGVSDGTEYWIVRNSWGEPWGERGWMRIVTSTYKDGKGASYNLAVEEYYRCGAGWKGAPEGESETGWLRPGCQQLPCHHDCGKPFAWQRCNL
The following text describes a protein:
Function:
Potentiates primary root protophloem differentiation. Required, together with VCC, for embryo provasculature development and cotyledon vascular complexity and connectivity. Regulates roots architecture. Mediates the recruitment of ASK7/BIN2 to the plasma membrane.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Polar localization at the apical side of the plasma membrane, shootward oriented, in developing root protophloem cells. Also found in the cytoplasm in the early, dividing. protophloem cells.
Sequence:
MNPATDPVSAAAAALAPPPQPPQPHRLSTSCNRHPEERFTGFCPSCLCERLSVLDQTNNGGSSSSSKKPPTISAAALKALFKPSGNNGVGGVNTNGNGRVKPGFFPELRRTKSFSASKNNEGFSGVFEPQRRSCDVRLRSSLWNLFSQDEQRNLPSNVTGGEIDVEPRKSSVAEPVLEVNDEGEAESDDEELEEEEEEDYVEAGDFEILNDSGELMREKSDEIVEVREEIEEAVKPTKGLSEEELKPIKDYIDLDSQTKKPSVRRSFWSAASVFSKKLQKWRQNQKMKKRRNGGDHRPGSARLPVEKPIGRQLRDTQSEIADYGYGRRSCDTDPRFSLDAGRFSLDAGRFSVDIGRISLDDPRYSFDEPRASWDGSLIGRTMFPPAARAPPPPSMLSVVEDAPPPVHRHVTRADMQFPVEEPAPPPPVVNQTNGVSDPVIIPGGSIQTRDYYTDSSSRRRKSLDRSSSSMRKTAAAVVADMDEPKLSVSSAISIDAYSGSLRDNNNYAVETADNGSFREPAMMIGDRKVNSNDNNKKSRRWGKWSILGLIYRKSVNKYEEEEEEEEDRYRRLNGGMVERSLSESWPELRNGGGGGGGPRMVRSNSNVSWRSSGGGSARKVNGLDRRNKSSRYSPKNGENGMLKFYLPHMKASRRMSGTGGAGGGGGGGWANSHGHSIARSVMRLY
The following text describes a protein:
Function:
May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer.
Subcellular Localization:
Cytoplasm. Nucleus. Note=In epithelial cells localized predominantly in the cytoplasm and occasionally in nuclei.
Sequence:
MASPGIEVELLGKGHSDLGEVAPEIKASERRTAVAIADLEWREMEGDDCEFRYGDGTNEAQDNDFPTVERSRLQEMLSLLGLETYQVQKLSLQDSLQISFDSMKNWAPQVPKDLPWNFLRKLQALNADARNTTMVLDVLPDARPVEKESQMEEEIIYWDPADDLAADIYSFSELPTPDTPVNPLDLLCALLLSSDSFLQQEIALKMALCQFALPLVLPDSENHYHTFLLWAMRGIVRTWWSQPPRGMGSFREDSVVLSRAPAFAFVRMDVSSNSKSQLLNAVLSPGHRQWDCFWHRDLNLGTNAREISDGLVEISWFFPSGREDLDIFPEPVAFLNLRGDIGSHWLQFKLLTEISSAVFILTDNISKKEYKLLYSMKESTTKYYFILSPYRGKRNTNLRFLNKLIPVLKIDHSHVLVKVSSTDSDSFVKRIRAIVGNVLRAPCRRVSVEDMAHAARKLGLKVDEDCEECQKAKDRMERITRKIKDSDAYRRDELRLQGDPWRKAAQVEKEFCQLQWAVDPPEKHRAELRRRLLELRMQQNGHDPSSGVQEFISGISSPSLSEKQYFLRWMEWGLARVAQPRLRQPPETLLTLRPKHGGTTDVGEPLWPEPLGVEHFLREMGQFYEAESCLVEAGRLPAGQRRFAHFPGLASELLLTGLPLELIDGSTLSMPVRWVTGLLKELHVRLERRSRLVVLSTVGVPGTGKSTLLNTMFGLRFATGKSCGPRGAFMQLITVAEGFSQDLGCDHILVIDSGGLIGGALTSAGDRFELEASLATLLMGLSNVTVISLAETKDIPAAILHAFLRLEKTGHMPNYQFVYQNLHDVSVPGPRPRDKRQLLDPPGDLSRAAAQMEKQGDGFRALAGLAFCDPEKQHIWHIPGLWHGAPPMAAVSLAYSEAIFELKRCLLENIRNGLSNQNKNIQQLIELVRRL
The following text describes a protein:
Function:
Probable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates.
Subcellular Localization:
Nucleus.
Domain:
The ZIP domain (80-130) is necessary and sufficient for the interaction with ZPR3.
Sequence:
MMMVHSMSRDMMNRESPDKGLDSGKYVRYTPEQVEALERVYTECPKPSSLRRQQLIRECPILSNIEPKQIKVWFQNRRCREKQRKEAARLQTVNRKLNAMNKLLMEENDRLQKQVSNLVYENGHMKHQLHTASGTTTDNSCESVVVSGQQHQQQNPNPQHQQRDANNPAGLLSIAEEALAEFLSKATGTAVDWVQMIGMKPGPDSIGIVAISRNCSGIAARACGLVSLEPMKVAEILKDRPSWLRDCRSVDTLSVIPAGNGGTIELIYTQMYAPTTLAAARDFWTLRYSTCLEDGSYVVCERSLTSATGGPTGPPSSNFVRAEMKPSGFLIRPCDGGGSILHIVDHVDLDAWSVPEVMRPLYESSKILAQKMTVAALRHVRQIAQETSGEVQYGGGRQPAVLRTFSQRLCRGFNDAVNGFVDDGWSPMGSDGAEDVTVMINLSPGKFGGSQYGNSFLPSFGSGVLCAKASMLLQNVPPAVLVRFLREHRSEWADYGVDAYAAASLRASPFAVPCARAGGFPSNQVILPLAQTVEHEESLEVVRLEGHAYSPEDMGLARDMYLLQLCSGVDENVVGGCAQLVFAPIDESFADDAPLLPSGFRIIPLEQKSTPNGASANRTLDLASALEGSTRQAGEADPNGCNFRSVLTIAFQFTFDNHSRDSVASMARQYVRSIVGSIQRVALAIAPRPGSNISPISVPTSPEALTLVRWISRSYSLHTGADLFGSDSQTSGDTLLHQLWNHSDAILCCSLKTNASPVFTFANQTGLDMLETTLVALQDIMLDKTLDEPGRKALCSEFPKIMQQGYAHLPAGVCASSMGRMVSYEQATVWKVLEDDESNHCLAFMFVNWSFV
The following text describes a protein:
Function:
High affinity heme transporter involved in the assimilation of exogenous heme during conditions of low cellular iron.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Vacuole membrane; Lipid-anchor, GPI-anchor. Note=Localizes from the cell membrane to the vacuolar membrane in the presence of heme.
Sequence:
MISLKIYFVLIFLFLKGINSAYVSNEEGETVDFTFSGFYANLTYPNEISELNYVEGNYLSTRIVRFNGSFYCDTTILSETNNVTGSCYVANCANDTVLEICDSGKEVHFTDMSGTTWSADTFTENLYWFCGGDGNKPNMTTAAAMNSDIDSYYVYGNWTIDTADSTVADYTCNYTHFQEAGDIEKGDVYTASADSSDSSSASSTIFKPSYFISCLLSVGLYLVLNF
The following text describes a protein:
Function:
May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Domain:
There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding; The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
Sequence:
MNVDLRLIVRLLLAILLTSLVTTILMGKQIHRRLVKSMVKTTGEKDSLPARQLPKREISPKVADFPPPLTLNQTELDILKIQRNNSFRLPQQEAIKEWQDAIFFKEDSNRRGLGEQGRAVQLPNAKLNPDDFQDFYAELSDRIPLNRSLPDTRPISCRKRKYLENLPNVTVIIAFHDEHLSVLLRSITSIINRSPVELLKQIVLVDDDSNLPELGQQLEEIVAQNFPKIIHILRLPERRGSIKARMEAIRVSSCQVLVFLDSHIEVNTNWLPPLLEPIVINPHIVTRPILDAISRKTFAYAKQNTMTRSGFNWWLESESLPIFPEDKSPDSTPYRTPVLSGAMAIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGGMMLYVPCARVGHIGKRPMKSISSPGYHNFLARNYKRVAEVWMDNYKKYVYDKNPKLYKMANAGLLFQRKTKRNALECKTFDWYMTKVAPDFLKRYLALDSPLVFSGVIESVAFPGFCVDSLNCRHTKPVVLARCTGHNSMPGEHQNWSLTQDHEIQLTNSKDDCLEAQGLRSKSVWLFRCHKNGGNQYWYYNHRHRWIQQGQIWVWCLEAQLASGHKVGKVLANKICDKNQLEQQWKVGRNAPYDPQREPH
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MIMTESGEVIDLDPPTETSQEQEDLLIVKVEEEDCTWMQEYNPPVFETFYQRFRHFQYHEASGPREALSQLRVLCCEWLRPELHTKEQILELLVLEQFLTILPEEFQTWVREHHPESGEEAVAVVENIQRELEERRQQIVVCPEVLPQKMVPPGVVQESLSHQLLSVEPQSEQEPQKPHILDENALPALHVPSLPLKDSQELTASLLSAGSQKLVKIEDVADVAVSFILEEWGHLDQSQKSLYRDDRKENYDSITYMDYESGNDNVELVVKQISDDAESHWMTAGSTERNVPQSQGFGEVSDLHGMVERWQVNPAVGKSRQNPSQKRDLGSITDANRKQSTSGERGHKCNDCGKFFLQASNFIQHRRIHTGEKPFKCGECGKSYNQRVHLTQHQRVHTGEKPYKCQVCGKAFRVSSHLVQHHSVHSGERPYGCSECGKNFGRHSHLIEHLKRHFREKSQRCSEKRSKNTKLNVKKKISEFSEADVEIPGRIQRNVSQVQDFGEAHEHPGKLDRKQGVPVKEVLGHPSSKRINFSEVTYVHKKSSTGERPHKCNECGKSFIQSAHLIQHQRIHTGEKPFRCDECGKSYNQRVHLTQHQRVHTGEKPYTCHLCGKAFRVRSHLVQHQSVHSGERPFKCNECGKGFGRRSHLAGHLRLHSREKSHQCHECGEIFFQYVSLIEHQVLHMGQRNEKNGICEEAYSWNLTVIEDKKIELQEQPYKCDICGKAFSYSSDLIQHYRTHTAEQTNKCDICRENVGQCSHIKQHQKAYSNVKSHQCNECGRGFTLKSHLNQHQRIHTGEKPFQCKECGMSFSWSCSLFKHLRSHERTDAINTVSV
The following text describes a protein:
Function:
Transcriptional regulator; binds to the promoter region of Cp15. Also binds to its own promoter, thus having a probable autoregulatory role.
Subcellular Localization:
Nucleus.
Sequence:
MIKSTTNPQEQRLPRPEDQSPAPPPPPPSSATTSTAAPATPTHQVATVIANMDTLKTAFLPNLSMDPNVHVSPHYCPMCHQQFERPQHVADHMQLCHGITLNAQGAIATLDGGHPQAQQHPKLSHPCFNCDEKFGNAVDLDEHHRLAHQTPAFLSRCLMCSIYGIHSATQQPNEYKCTQCGSICTTAMLAAGQQGFMEQQEAAVTPDDQLPAMAPRDMRLTPEEQHHQQQLQAEHHHQQQHQQQQQQQQQQQELLEQQQREMQEQAQQQQVHHHQQDQDLAGDQVALKVPPLTVKLNKNANGGAIVSHPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPGVPAPASSGVLVGTQTVPADLAHKIRHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFRCGYCGRAFTVKDYLNKHLTTHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKLHPL
The following text describes a protein:
Function:
Acts as a negative regulator of WRKY33 transcription factor activity in the promotion of defense gene expression. Acts as a negative regulator of pathogen-associated molecular pattern (PAMP)-induced responses to modulate resistance to pathogens.
Subcellular Localization:
Nucleus.
Sequence:
MENSPRYREATNLIPSPRCHNSNNSCGMSSSSESNKPPTTPTRHVTTRSESGNPYPTTFVQADTSSFKQVVQMLTGSAERPKHGSSLKPNPTHHQPDPRSTPSSFSIPPIKAVPNKKQSSSSASGFRLYERRNSMKNLKINPLNPVFNPVNSAFSPRKPEILSPSILDFPSLVLSPVTPLIPDPFDRSGSSNQSPNELAAEEKAMKERGFYLHPSPATTPMDPEPRLLPLFPVTSPRVSGSSSASTS
The following text describes a protein:
Function:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Sequence:
QLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWKPEDCRRFYREHEGRFFYQRLVEFMTSGPIRAYILAHKDAIQLWRTLMGPTRVFRARHIAPDSIRGSLGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEEGIHCAAETGGPKPA
The following text describes a protein:
Function:
Essential for sporulation and seems to have a role at the time of, or after, initiation of nuclear division. Appears to have a role in outer spore wall formation.
Miscellaneous:
MISCELLANEOUS: Present with 3000 molecules/cell in log phase SD medium.
Subcellular Localization:
Spore wall.
Sequence:
MYKNYYSNTEVYKKHKDSGSLRKKALRSRRSSFFSFFNDSSSSNGNEFIGFRRFAKAYLFGREIGSCGTDSYTPVGANVNKRRLKKEDKNDQQLWKRQHHSQGCFFPIDDDSNKQTEAAVNKFYENGEYVNQDLIFKGKVYSEESEVVDEKTAGSQNPALLKTRSISLNDIPRGTGISSVLSQVRGGSLERIIVYRYDTPERSLHKVDLFFLNYEGAQSFMRYAKTNIFKVNGVQLKPEWIFLESTYENIMKEQSVNRIIEEEKFISRCLIVKKSSTTAMPNKSNLNKGQTLENIDIQELEKDFQNFGEVLEITPIVSRKLCVSIFFYDISSAMRAMEEYEQKGSYLYNKYFKTWTIWYGKDITDQPCIDL
The following text describes a protein:
Function:
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MIRNFTKGLLINNLNINKFGSTKIRPFCSTITKNDKNNVINILKKRGFIHQMTASDIEMIKMTSTNNNNNNDNNNNNNNNKVSLYAGFDPTADSLHIGNLLTLMVMLHFKRHGHNPIALMGGATALIGDPSGKSSDRVMLTEEFIEGNLKHIRENITAVLGEDTLVVNNIEWNKTMDVISFLREVGSYFRVGSMIKKDFIQNRLSDSNENGISFTEFCYSLFQANDFAHLFLKHGCSIQIGGSDQWGNITAGCDLIRKKLKGNAQGITIPLLTNSAGKKLGKSEGNSIWLSPHRTSPYKFYQYWIQVSDEDVERLLKLFTLIPLEEISILVQKHNENPHLRLGQKTIAEHVTRLIHGQKGVEEALNTTELLFGESNKLLTPNASTTKIGDFDIGYLLSRVNFIELERSKFVDNQTEPILNLFAQISDASKSKVKQLLQSKSIYLNNIPVASNSQFIQSSDLIANDFIYLKSGKKIYYLIKFI
The following text describes a protein:
Function:
Acts as a chain editing deubiquitinating enzyme that binds and cleaves 'Lys-48'-linked polyubiquitin chains, with a preference for chains containing four or more ubiquitin molecules thereby modulating protein degradation by the ubiquitin-proteasome pathway. Probably by regulating the IGF-1-insulin-like pathway, regulates lifespan. Regulates germline DNA double-strand-break repair and apoptosis in response to DNA damage by recruiting E4 ubiquitin-protein ligase ufd-2 to DNA repair foci. Interacts with key regulators of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNFKQLIYWEKQGYDQLCGVHCINSLLQGPYFNEVDLATIAQELDRQEIELLGKTGRRFKSQNVAEDGNFSIQVLAEALKKLGDLSIESIDSKLNQNQDLSQESGFICNSSAHWFAIRKIDNVWYNLNSTNKRGPEIISDFYLSAFLLSVKENGYQIFVVKGVYPPPQLDNINQNDRQKVLTAQFVKQVHDRRVKRKNYKLNIGGSDEVEMEKALKASKGEKYESTDEEFEEEEVQQPQKKQSTPKFQGQGIQFGFQQSIANYQNFNIDQDDAEYRSIILMTLEQKFSFQLEEGIVILFQMPDGKNKQYTFSYDAAVEDLYDFVFYESRQSPMKFTLVCPIQKLQLLDVSQLLLDIGVDTMTQIIVKKE
The following text describes a protein:
Function:
Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Domain:
There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding; The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
Sequence:
MIASLIRSRRRSRRCVVYSVFLFGFLALWGSFALALVFLSDMYIGEDQISTQKAIKPIARSNYHVVVGHYNGNLPEDKKRNLTSEELNANLYAPHDDWGEGGAGVSHLTPEQQKLADSTFAVNQFNLLVSDGISVRRSLPEIRKPSCRNMTYPDNLPTTSVIIVYHNEAYSTLLRTVWSVIDRSPKELLKEIILVDDFSDREFLRYPTLDTTLKPLPTDIKIIRSKERVGLIRARMMGAQEAQGDVLTFLDSHCECTKGWLEPLLTRIKLNRKAVPCPVIDIINDNTFQYQKGIEMFRGGFNWNLQFRWYGMPTAMAKQHLLDPTGPIESPTMAGGLFSINRNYFEELGEYDPGMDIWGGENLEMSFRIWQCGGRVEILPCSHVGHVFRKSSPHDFPGKSSGKVLNTNLLRVAEVWMDDWKHYFYKIAPQAHRMRSSIDVSERVELRKKLNCKSFKWYLQNVFQDHFLPTPLDRFGRMTSSSNSSVCLAWTLRSSGIKTASTADCLKIFHKTQLWLYTGDRRIRTDEHLCLSVVQLLHTTSDWKIQLKECAGFDTEYWDFKPKIGRFQNRKTGLCLASPDIFDPTKDEFNPPIVQKCRSSNDRQNWTITEMSWLPEHP
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, flagellum basal body.
Sequence:
MKSMFDVRKEKLKQKIQSKYTEFKQHEHLVNQAVEDKWIQILDNEYLTDTKEKIYKLQAHYQLQLDRCDSVVKRLQDWIEENEEQYQFNLLANRRTLNDLHELSQKRLKTERERWESRLKTIVDDFEDSRSRVIKNYQDHVSEMRNINSAIGFEYKERRDVLDNKFRFEKDALTMRSQESISALNMHLMEQITQVNEQMKLANKEYKEKSENKMTQFHQLFEEHKKMQREMRENEKAIAKHAADISHWRRKIKNNMTESKEENDRLRQEKETLSLHFRKLKDVMARFRATEAAKLAEISVAFEDTINALQKKLQLADNILKYSEMTRKLETEREQIIPFPNSIADDDPEIQRQMRNFKLQLKGDSKYVEESDVFDKFYRRYNKCLLDTLSLQREKAQLTEENKYYKNLLQKYMENLGVREDAVNKPNTIVIVNQNTNAPKSGPPEDTIPTRDVPLVIQQTKLQGY
The following text describes a protein:
Function:
Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MYRSHNNNNNYHSRNDGSNGRINKPRDPKSQDKYVAYQQNIEQQLASQEKKQAYRRITDHGNNMGRWYIEKSLGLTNRSQQAIGTIRPESSYLIDLLPSLAYSSSFNLNRRNNKNNLAVLDLQTKFVHLSSNKVKHTINTVKWTPEGRRLLVASHSGEFTLWNGMTFNFETIMQAHESPILTMKYSNHDEWLLSGDQNGTVKYWQPNFNNVNNISAHANGVRDIAFSPNDSKFLTCGDDSAIKIWNFNNGKEERTLSGHHWEVKSADWHPNLGLIVSGSKDNLVKLWDPRSANCVSTLHGFKHTVNKTRFQPNGTARLLASVSRDRSCRIFDLRTMKDMLVIRDSETDLSCVAWHPIHASMVTTAAYNGSISNFLLDSYIPDSNESVPKRSNNNSNLSTNTNNTIDAVQKIPYAHEKAIHAVEYHPLGHLLCTAGSDKTARFWSRARPNDPMAWKDAVYTDCKAGAWYYSVNNNVNAVMEDPNAVKNEDDEIANNDDPLSNSGRRRGVGASASGGATGSVPGLRSRNETPNNGSYAIPGLRGF
The following text describes a protein:
Function:
Vacuolar Fe(2+) uptake transporter.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MAVRNDLCIPGLEDKSEQENRVSVEEEFDYSERRKWLRSVKQDAKAMVPTGFSGLVAGVCSMAIGELVSVYTQRSLEVALVKRETTIVEKEKSTHLYRSSYYMFYLL
The following text describes a protein:
Function:
Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2.
Miscellaneous:
MISCELLANEOUS: Present with 2420 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MVRILPIILSALSSKLVASTILHSSIHSVPSGGEIISAEDLKELEISGNSICVDNRCYPKIFEPRHDWQPILPGQELPGGLDIRINMDTGLKEAKLNDEKNVGDNGSHELIVSSEDMKASPGDYEFSSDFKEMRNIIDSNPTLSSQDIARLEDSFDRIMEFAHDYKHGYKIITHEFALLANLSLNENLPLTLRELSTRVITSCLRNNPPVVEFINESFPNFKSKIMAALSNLNDSNHRSSNILIKRYLSILNELPVTSEDLPIYSTVVLQNVYERNNKDKQLQIKVLELISKILKADMYENDDTNLILFKRNAENWSSNLQEWANEFQEMVQNKSIDELHTRTFFDTLYNLKKIFKSDITINKGFLNWLAQQCKARQSNLDNGLQERDTEQDSFDKKLIDSRHLIFGNPMAHRIKNFRDEL
The following text describes a protein:
Function:
Transcriptional activator of nphA1 and nphA2 involved in the degradation of 4-nitrophenol (4-NP).
Sequence:
MAEREQSNDSARTDVPAIVSLRTRELDTGEGRMQWASTLERLYCETDVAWPEPRRHFDAEWGGRPFGDLHVSTIRADAHTVVRSPAMIQSDSGEGYLVCLVTDGSVEVRQSGRATVVEPGSFALLDCAAPFVFHSPAPFRQVVVRSPREVLTSRLPGRIVEHGTARSIHGDTGAGGLVGRLFVDIADMDAPMSQGAAVSFASSAVDMLATALTEGLLATSAADLHRTEDLTRVQRVIEQNLHDADITLSDIAAAAGMSLRTVHKLFNAEGTTTRAWLYQARLEAARRYLLTTDLSVADVSECAGFRDVSHFSRLFRSTFGSSPGLYRKEHARIGS
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex receptor (SR) (By similarity). Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity). May mediate the membrane association of SR (By similarity).
Miscellaneous:
MISCELLANEOUS: Present with 8250 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MLSNTLIIACLLVIGTTIALIAVQKASSKTGIKQKSYQPSIIIAGPQNSGKTSLLTLLTTDSVRPTVVSQEPLSAADYDGSGVTLVDFPGHVKLRYKLSDYLKTRAKFVKGLIFMVDSTVDPKKLTTTAEFLVDILSITESSCENGIDILIACNKSELFTARPPSKIKDALESEIQKVIERRKKSLNEVERKINEEDYAENTLDVLQSTDGFKFANLEASVVAFEGSINKRKISQWREWIDEKL
The following text describes a protein:
Function:
May regulate the subcellular localization of CIP/WAF1.
Subcellular Localization:
Nucleus.
Sequence:
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
The following text describes a protein:
Function:
Binds to all microtubule populations.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MKYSDPCTIRVLAPPGGKDSISFGVSDLGENSAQVKACQVERNKSNIFVGDVDKVMKYSDPCTIRVLAPPGGKDSISFGVSDLGENSAQVKACQVERNKSNIFVGGDLNLPHKGNAKSCQEARQRSQVFTAPNEPLPVKPSTAHGKNSGDIIRANSQDEPQRTSVRTHAPPGGASHIVLG