lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates.
Sequence:
IDTVVAACVVAASTVSAPSPSTPPPVPPRRRRCRRPLQAVADLDLLRLSESVKQEPGAGAIVAAEQQGSPVGITVKLDISVLQCPICFRPFKPPIFRCKGGRHTACESCLAEIPYKQCQECEHGGGFERPVPGAGRDSLLRPDPCAHDGCSLFVPYHEASQHQSVCPHAPCSCPEPGCFFQAPPVALLAHLTASHAMPVHKVPHAKLLAMGMGLPPRRHLVVVEDDSGFLLTVAGCPAGITTVSAVYVMVHGEAVGQRAAPGASAGDRVGGDRGGLLRGARGRLHGGAARVDGAGQLGNFLVGAGASKELRLNIRVEKMS
The following text describes a protein:
Function:
The GAL3 regulatory function is required for rapid induction of the galactose system. At normal induction, galactose in the presence of the GAL3 protein may lead to the induction of the GAL genes, including GAL1. Then the galactokinase protein (GAL1) in the presence of galactose may reinforce the induction leading to a higher expression level. Upon depletion of galactose, the inducing activity of the galactokinase protein may decrease, after which transcription of the GAL genes, including GAL1, may decrease.
Miscellaneous:
MISCELLANEOUS: Present with 721 molecules/cell in log phase SD medium.
Sequence:
MNTNVPIFSSPVRDLPRSFEQKHLAVVDAFFQTYHVKPDFIARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFDLPLDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTPLVGAQIFCQSDIPTGGGLSSAFTCAAALATIRANMGKNFDISKKDLTRITAVAEHYVGVNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQLKNHEISFVIANTLVKSNKFETAPTNYNLRVIEVTVAANALATRYSVALPSHKDNSNSERGNLRDFMDAYYARYENQAQPWNGDIGTGIERLLKMLQLVEESFSRKKSGFTVHEASTALNCSREEFTRDYLTTFPVRFQVLKLYQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIETNQICSIALANGSFGSRLTGAGWGGCTIHLVPSGANGNVEQVRKALIEKFYNVRYPDLTDEELKDAIIVSKPALGTCLYEQ
The following text describes a protein:
Function:
Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate BMAL1-dependent phosphorylation of CLOCK. However, the physiological relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock.
Subcellular Localization:
Nucleus. Cytoplasm, cytosol. Note=Predominantly localizes to the nucleus, where it co-localizes with CLOCK. At the G1/S boundary, partially translocated to the cytosol.
Sequence:
MRLLTRRAGHGAATLALRVIHMQRVPVLRLPAILDMERKIPSRESPRRLSAKPGRGTEMKKLARPLGVVAADSDKDSGFSDGSSECLSSAEQMESEDMLSALGCKREDKRRQPSKAADTALPTLPPMVVMKSVLVKQGSSSSQLQSWTVQPSFEVISAQPQLFVLHPPVPSPVSSCQTGEKKSESRNYLPILNSYTKIAPHPGKRGLNSEDRGTSGVSKKLCTERPGPSLSSSEPAKTGRVLSSPSTPAPPSSKLTEDSTLQGVPSLGAGGSPQTLQPVSSSHVAKAPSLTLASPASPVCASDSTLHGLESSSPLSPLSASYTSPLWAAEHLCRSPDIFSEQRQNKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQAELDQLKEQTQMFIEATKSRAPQAWAKLQASLTSGSSHSGSDLDTLSDHPDV
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MGVTIVGLCAIPPEKTSQQVIDVLVKRLTNLFADVVGVWSLDFEHYQANTDSLSSKNVVYSLAWSDNNTKYIMHNNDDGQIVPMESADEFTDNIKNYTLRKSLKAHGQTLLLGDFIVKLSSIVGGHTSLTDIVIEANYKPCSHVGVCWNLLHEFCKILTESYELSLPETPPLNILGDGTFDKSQTATQYADIFINHKKAVTKSL
The following text describes a protein:
Function:
Catalyzes the formation of chlorobenzoyl-CoA via a 2 step reaction. First 4-chlorobenzoyl is adenylated by ATP, followed by acyl transfer from the 4-chlorobenzoyl-AMP intermediate to CoA. Benzoate, 4-bromobenzoate, 4-iodobenzoate and 4-methylbenzoate also act as substrates. Inactive towards 4-aminobenzoate, 4-hydroxybenzoate, 2-aminobenzoate, 2,3-dihydroxybenzoate, 4-coumarate and the aliphatic carboxylic acids palmate, caproate, laurate and butyrate. Negligible activity is detected when ATP is replaced by UTP, CTP or GTP as cosubstrate.
Sequence:
MQTVHEMLRRAVSRVPHRWAIVDAARSTFDICRTGETSRNEGSATARLWPQPARPLAVVSGNSVEAVIAVLALHRLQAVPALMNPRLKPAEISELVARGEMARAVVANDAGVMEAIRTRVPSVCVLALDDLVSGSRVPEVAGKSLPPPPCEPEQAGFVFYTSGTTGLPKGAVIPQRAAESRVLFMATQAGLRHGSHNVVLGLMPLYHTIGFFAVLVAAMAFDGTYVVVEEFDAGNVLKLIERERVTAMFATPTHLDALTTAVEQAGARLESLEHVTFAGATMPDTVLERVNRFIPGEKVNIYGTTEAMNSLYMRAVRIAGTVMRPGFFSEVRIVRVGGDVDDGCPTVKRASWRWRRRMRPFQATLTNLRLLQKSFRKAGTGRAICVRDGSGNIVVLGRVDDMIISGGENIHPSEVERILAAAPGVAEVVVIGVKDERWGQSVVACVVLQPGASASAERLDAFCRASALADFKRPRRYVFLDELPKSAMNKVLRRQLMQHVSATSSAAVVPAPAVKQRTYAPSGRAIAR
The following text describes a protein:
Function:
Transcription repressor that inhibits transcription of srl/PGC-1-alpha to negatively regulate mitochondrial biogenesis and thereby promotes neurodegeneration. In neurons, functions downstream of the Pink1-park pathway and is likely to act as part of the Pink1-park homeostatic mechanism that maintains mitochondrial quality and function through degradation (mitophagy) and synthesis (biogenesis).
Sequence:
MAEICRVCMDISGKLVNIFDARRRTRVSIAEMIAQCTGFEVKRGDLFSEMICPQCYEDVKSAYGIRQTCEESHQFYCRVRDEGIEDALCALLEEEDWEISEDEDARIDSASAADDDGKSDSKKVAFECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVHNAERTFKCPHCASFYKQRKTLARHILEIHK
The following text describes a protein:
Function:
Involved in rRNA processing.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPADKKQRKGAHPYRKPRPNPSDPSSSDKPARPKPTHRIPATEARDGAGIPGLSKLKSSIRQTKRLLAKENLEPGLRVSTQRRLTSLEADLAAAERREVERKNGAKYHKVKFFERQKLVRLIKRFKRKLLDSETSSKKRSKHEEELLDARIMLNYVLHYPNTQKYISLFPSNPNQTEDEDDDDDSSKPKLKLPPLLHPVPSTEECEKMDKPTKRRYDLLLETKRLMEESKLKSEPETDLKKGQVDGVVVGLGADVQIGLGDKKEAKQNAAQGTGEEEDDFFESGDE
The following text describes a protein:
Function:
Acts as a cell end marker required for efficient new end take-off (NETO), whereby growth is activated at the cell end to generate bipolarity in extending cells. Also required for proper placement of the septum.
Subcellular Localization:
Cell tip. Note=Present at both poles of the cell throughout the cell cycle whether they are growing or not. Located at the division site at time of cytokinesis.
Sequence:
MVQKVLSRQSDNSQDVSAEQLDVVESGSIDQQNIRAWVVRKVKENDKRTSTNQSFKWEAVKPASCLDAANEKFMYLHGGREKSGISNSLFKLDLDSCTVYSHNRGEDNDSPARVGHSIVCSADTIYLFGGCDSETDSTFEVGDNSLYAYNFKSNQWNLVSTQSPLPSPRTGHSMLLVDSKLWIFGGECQGKYLNDIHLFDTKGVDRRTQSELKQKANANNVEKANMEFDETDWSWETPFLHSSSPPPRSNHSVTLVQGKIFVHGGHNDTGPLSDLWLFDLETLSWTEVRSIGRFPGPREGHQATTIDDTVYIYGGRDNKGLILNELWAFNYSQQRWSLVSNPIPILLSDSSSYKIVSKNNHILLLYLNALDAPKQLLCYEADPKNLYWDKDKFSDIPVLQHISMKPSNASNHTVSLGYLNDRPNHSKKNSVTSTSSSQFNNFLEQNQKAVRSARHRHYASLDEQGLHSLRNLSKTSGMNHSADFSLHEFGQADPFAYEIEKPIASLPLPNGNDTISRSSESSSPINESESNSLLKLQSDFKFSNSDDRVAWLEEQLLYCMQQGYTLKPPNLFQHVDEKLRLEKKEQLSYLEILKVIEQMLESNEQKFKKQIVSLASENAKLAAQRDAAVENANYSRSLIQKKTTDETVGSLIEKVGKLEYEVQGTLEEATSYYQKNTELQQLLKQNESASELLKSRNEKLCVDYDKLRSVFEEDSSKILSLQKENENLQSQILQISEELVDYRSRCEALEYGNYELETKLIEMHDRVEMQTNVIEASASALDVSNTAILSFEDSLRRERDEKSTLQQKCLNLQYEYENVRIELENLQSRALELESALEQSVSDAKYSKAIMQSGLSKLLSSINENKDNLKEFSKSKQKISYLESQLEGLHELLRESQRLCEGRTKELLNSQQKLYDLKHSYSSVMTEKSKLSDQVNDLTEQAKITQRKLSEVQIALADSKMNQQLSGKDSTDVHLPTDFSASSSPLRSYFNEEDSFNNASAAHSSKESDIPSGGVFTKYRNHFGNLMTSEETKAPDNNDLHKRLSDVINSQQKFLSLSPQVSKDYYDVRSKLNDTAGSFSGEEMRAIDDNYYASRIKQLEDDYQKAITYANCSDESFQQLSHSFM
The following text describes a protein:
Function:
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
Sequence:
MRIVAMIMAGGEGTRLSVLSEKRAKPSVPFAGKFRIIDFTLSNCVNSGIFDVAVLTQYRPHSLNEHIGIGKPWDLDRARGGVRLLQPYQGRRDESWYRGTADAIYQNLNYIQERRADLVLILSGDHIYKMNYNDIIKTHLQKRADLTVAVMEVPIEETDRFGIMTTDEHDRIIEFTEKPKARDKGNLASMGIYVFNADILIRRLSEGGPEKPRIDFGKDVIPAMVAEDRVFAHRFKGYWVDVGTIQSYWETSMQLLDPSLDFDLFDPNWLIRTRSEERPPAKIGPQAKVTQSIICNGCTIRGTVIHSVLSPGVYVSPGAIVRDSVVMNDTWIGPGAVLDRVIVDKKVVVGAGARLGFGDDLTVPNRKQPDKLNSGVTVVGKSAHIPAGITIGRNVVINADRDAEDFPAGDVPSGETI
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MAEEEGSANEAVALKHKFQDLISELKRSSESTLDASNSFCQDFCQILMHHGCQWRPDEDLLPLLELYTAAIMCCAEASPFLSPECEHVTDVLNKLSWSCLNLLLSFSEQIPGALWEKFQTSVKMAHGILQAHGNSQLQALLTLAEDNGIWSNATLCSILSNDLPNVERVHEFLSREGAELLHMRIKHLIKEKDMEKAARLAKTCAEFPEFGGKKNFRQIYLVCLCEITPQQELMHEIKEVDCKEALDMICNLESEEDEKGALSLCTAFFKRQLLSGDAYCAWELTLFWSKLLIRLESKQAFLEQCRLLARLSESVYHILLLIKVIQAEVDTDGLSVCIEMCIQALKMGVHDNEDCNITICKTISCLLPLDLEVKQACQLTEFLIKPSLESYYAVETLFNEPDQKLDQEDPPILNSLRCDLLLALKIKWPFDPEFWDWKTLKRQCLALMGQEATAILSSDKFTDSDDNEFHDLDEKYFQHFTDNPSYELFEVGTERKKKKNEFKKVKEKGFVSARFRNWQAYMQYCVLCDKEFLGHRIVKHALKHVQDGVFRCPICAKTFDSRTVLEPHVASHVKQSCSERLAAMGVSKKRTDPKLTPASSTLKKEEHYSDTAAKVSQENTCNNNLYTSIGSTSTDVKSKTKSSSSSTSSSSSPKQGNPIRDVNNTKDCCCPVTSCQKVFKYFRNLVAHVKAHKNEQEATDFLQLQSRKAMCQYCHRQFVNLTHLNDHVQMHSGDKPYFCVQLGCNCRFSSHAELLMHRKLHAEFQAQCAYPNCERIFNETYLLYDHEAQHYLTFPCKSHNCDKVFYTLAELDLHQRGHAKQVDHSAIDRRSHLHLEVAPQACPASELPQNQIKDFTPVEIKCSVQNIAGTTQDSTVQPEHLVLHTAQLKETENNSETSAVEPESTTSHCPQKSKRLESCYVKLKPIPIKFNDAVYLNTLKNADTETQALLKDKKLFSFIKIPLKPPTPKSSLAVTKENREEHLTHICPFETCTRKYSTSKSLSRHVKNVHAEAFEEWKLSKKYKRIAQVASKKSSSKHMTTNMPTPLLVKKWKGCSQKTERVNLQESAIQSPSSIFTNHVNMQSIGTKFCSQFENPPSAASTNQSGLMQLPDAQAWALPSMESLSSGFSEHGSYSSTILSENQHTNPSYHSDTILDYPSASSYDDIIPLPGNAHAPSGVMNEASKYVSSSLRVLHALNGDQTCDLSQVESSVNLEDISISNDLHAGALSGQNVSLYFPSEASSVSMQSMENSNKEMSSECTDAAFASEIKCMSDILNPNFKESSEDFFGATPVNDDKTPDDFCNHEMALEGPEGITSDDQTVLDSGENRKCKKIKSSKRTKWPAIIQDGKVICCRCYREFSSTKSLGGHLSKRSQCKPVDEIDLTADLPVSFLDFLNDPDISTVQMPLPANDILEDNHKSFIYAPSESSTFNDNTLTSVHGTESIPNINANEPSQDHSEIATNPNLFNSPVSNTATEMIADTEIIPENAGEDGIILEIERALQRLDLVDVLSDKSVPESTNLQELSSKSDTRNDQQNTIKDPVQTEQKSVLKPFKCKEDACTYGAMTKEALFKHFSRVHDYSDERINEIKKNPDRLAPYGCHLCSKTFTRTTGLKIHYKNVHHFSKDEISVLKIGLGFRKPKKPAPESETVHSALIDKQANKSEKIQHQVDPKLTVSTVKSNVDGKPKIVSKKKKQATKSSLTVGTTKSCKTTEETQKNVGNLDRLSTTCIKLEAPAQNAESHASDLNHPGIFGAQELSGLSSPHLFNKVNATNEEYATPQFFGQIGTKSSVTEDTQEKTMAVGNTDCGDSVDVYRPYRCIHEGCVAAFSIQQNLILHYRAMHQSECDEKNSAKATDGVFPVQEYRCQVKQCSKVVSKVTSLLKHYLLLHRCTLEKASALLSGVEVGTFQCDQSKCSAHFTCHLKYIDHIKNDHKAIKVSVDGDFESVNLTFGCQFKGCDRVYTTKSNLLRHLMKKHDATFETMKAKQEHVGDSVQTKKSSANPNSNNGKENIAKDKTKTKKKSSKKKEDKAQSQRVTLEKPALKSNEEASALCTQTFPLQYPCMIKNCDSVMNDERNILHHYTTHGLTEQYIEDQRSQFIFCIKSSEIPAADSTSQNVEVKEAQISEAQNPNSDVSSQDVGPEPAKEVEVNEAVTAVPPVVKRKRGRPRKSDCRNKVSVERKQSLRNCSDEHVKCMLKVSGSILRASNSQGNHRKNKVALKLYKSSKFQTTVLKFSQNPLSNPSKRLRKLKPIIRTKDQVKRVVNFRNPLKIERVNNVKIVMYKNQSPGSRLLLKQLQDMQPRVILEKRLHS
The following text describes a protein:
Function:
Operates as a K(+)/H(+) antiporter or Na(+)/H(+) antiporter of the chloroplast envelope that functions in pH homeostasis and chloroplast development. Monovalent cation transporter with a preference for Cs(+), K(+) and Rb(+) relative to Na(+) or Li(+). Required for pollen tube guidance, but not for normal pollen development. May also be involved in the development or function of the female gametophyte.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=PubMed:15220473 shows a localization in chloroplasts while PubMed:21239645 shows a localization in ER.
Sequence:
MSSGAPLNVTNPNYDIEESRFGKIVCYDQSLLFEKREQKGWESGSTLASSLPFFITQLFVANLSYRVLYYLTRPLYLPPFVAQILCGLLFSPSVLGNTRFIIAHVFPYRFTMVLETFANLALVYNIFLLGLGMDLRMVRITELKPVIIAFTGLLVALPVGAFLYYLPGNGHPDKIISGCVFWSVALACTNFPDLARILADLKLLRSDMGRTAMCAAIVTDLCTWVLLVFGFASFSKSGTWNKMMPFVIITTAIFVLLCIFVIRPGIAWIFAKTVKAGHVGDTHVWFILGGVVLCGLITDACGVHSITGAFLFGLSIPHDHIIRNMIEEKLHDFLSGILMPLFYIICGLRADIGFMLQFTDKFMMVVVICSSFLVKIVTTVITSLFMHIPMRDAFAIGALMNTKGTLSLVVLNAGRDTKALDSPMYTHMTIALLVMSLVVEPLLAFAYKPKKKLAHYKHRTVQKIKGETELRVLACVHVLPNVSGITNLLQVSNATKQSPLSVFAIHLVELTGRTTASLLIMNDECKPKANFSDRVRAESDQIAETFEAMEVNNDAMTVQTITAVSPYATMHEDICVLAEDKRVCFIILPYHKHLTPDGRMGEGNSSHAEINQNVLSHAPCSVGILVDRGMAMVRSESFRGESMKREVAMLFVGGPDDREALSYAWRMVGQHVIKLTVVRFVPGREALISSGKVAAEYEREKQVDDECIYEFNFKTMNDSSVKYIEKVVNDGQDTIATIREMEDNNSYDLYVVGRGYNSDSPVTAGLNDWSSSPELGTIGDTLASSNFTMHASVLVIQQYSATKRQAAVTAAAATTVMGAVAGVTGNNLESAGGDAKMTRDAHEPFMKSMYEDEDEDDEEDHQYGIHR
The following text describes a protein:
Function:
Involved in hearing and vision as member of the USH2 complex. Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. Involved in the maintenance of the hair bundle ankle region, which connects stereocilia in cochlear hair cells of the inner ear. In retina photoreceptors, required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport.
Subcellular Localization:
Cell projection, growth cone. Cell projection, stereocilium. Cytoplasm. Synapse.
Sequence:
MNAQLDGLSVSSSSTGSLGSAAGAGGGGGGAGLRLLSANVRQLHQALTALLSEAEREQFTHCLNAYHARRNVFDLVRTLRVLLDSPVKRRLLPMLRLVIPRSDQLLFDQYTAEGLYLPATTPYRQPAWGGPDGTGPGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSISPPSGLPQPHGSALRQHEGDRRSTLHLLQGGDEKKVNLLLGDGRSLGLTIRGGAEYGLGIYVTGVDPGSEAESSGLKVGDQILEVNGRSFLNILHDEAVRLLKSSQHLILTVKDVGKLPHARTTVDETKWIASSRIGDTASNSSGFPGDLTAEGTNKLGFYKGPVGSQVTLSSLGNQTRVLLEEQARHLLNEQERATMAYYLEEYRGGSVSVEALVMALFELLNTHAKFSLLSEVRGTISPQDLDRFDHLVLRREIESMKARQPPGPVAGDTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGTMNTLSDVSLDDVKATSKGLPSYKPPPPPPPLAQGRDHPLTQARKPGREDLQPPSSASSHSGIVFSAPRNRSPPAGTAPTQEASSAQDSPPSPIYASVSPANPGSKRPLDAHLALVNQHPIGPFPRVQSPPHLKSPPAEALLLTGGAPPPPSPSGRPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQTRTASTLSQLSDSGQTLSEDSGVDAGEAEASAPGRGRQMASTKSRSSKETPRSERTTEGASKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGVTLRGKEHREAARIIAEAFKTKERDYIDFLVTEFNVTL
The following text describes a protein:
Function:
Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MPASEDRRGKWKRKKRGGLSAARKPKQEEEDMEEEDEENNNNNNEEMDDVENADELQQNGGATPDPGLGIGEVVEDSGSRISDFPAVVKRVVIRPHASVMAVVAAERAGLIGETRGQGSLPALENISFGQLQALSTVPADSLDLERSDGSSSAYVISPPPIMDGEGVVKRFGDLVHVLPMHSDWFAPNTVDRLERQVVPQFFSGKSPNHTPESYMEFRNAIVSKYVENPEKTLTISDCQGLVDGVDIEDFARVFRFLDHWGIINYCATAQSHPGPLRDVSDVREDTNGEVNVPSAALTSIDSLIKFDKPNCRHKGGEVYSSLPSLDGDSPDLDIRIREHLCDSHCNHCSRPLPTVYFQSQKKGDILLCCDCFHHGRFVVGHSCLDFVRVDPMKFYGDQDGDNWTDQETLLLLEAVELYNENWVQIADHVGSKSKAQCILHFLRLPVEDGLLDNVEVSGVTNTENPTNGYDHKGTDSNGDLPGYSEQGSDTEIKLPFVKSPNPVMALVAFLASAVGPRVAASCAHESLSVLSEDDRMKSEGMQGKEASLLDGENQQQDGAHKTSSQNGAEAQTPLPQDKVMAAFRAGLSAAATKAKLFADHEEREIQRLSANIVNHQLKRMELKLKQFAEIETLLMKECEQVEKTRQRFSAERARMLSARFGSPGGISPQTNNLQGMSLSTGGNNINSLMHQQHQQQQASATSQPSIIPGFSNNPQVQAQMHFMARQQQQQQQQQQQQQQAFSFGPRLPLNAIQTNAGSTASPNVMFGNNQLNNPAAAGAASINQPSFSHPMVRSSTGSGSGSGLGLN
The following text describes a protein:
Function:
Part of the ABC transporter FtsEX involved in cellular division.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSIIHYFSLHVESARSALKQLLRQPFGTLLTLIMLAVAMTLPLFMYLGIQSGQSVLGKLNESPQITVYMETAAAQSDSDTVRSLLTRDKRLDNIRFIGKEDGLAELQSNLDQNLISMLDGNPLPDVFIVTPDPATTPAQMQAIYRDITKLPMVESASMDTEWVQTLYQINEFIRKILWFLSLTLGMAFVLVAHNTIRLQILSRKEEIEITKLLGAPASFIRRPFLYQAMWQSIFSAAVSLGLCGWLLSAVRPLVDAIFKPYGLNIGWRFFYVGELGLVFGFVIALGVFGAWLATTQHLLCFKAKK
The following text describes a protein:
Function:
Facilitative glucose transporter required for the development of the cardiovascular system.
Subcellular Localization:
Cytoplasm, perinuclear region. Endomembrane system; Multi-pass membrane protein.
Sequence:
MGHALLILLLCSTVSLLGGLIFGYELGIISGALLQLQVDFHLGCFEQEVLVSSLLIGALLASLVGGIFIDRQGRRKAILASNAILLCGTLILTLAGSLLWLVCARMIIGFAISISSMACCIYVSEMVAAHQRGVLVSLYEVGITIGILLSYALNYLFSEIKEGWRYMFGLAVGPAVIQFLSILFLPKNSMNINVHYSGSRKNLIQIQKNEDGGGVMPLCPKEKQYYFVDLFKSKDNMRTRTLVGLGLVLFQQFTGQPNILSYASTIFRSMGYQSDSSAVLASVGLGVMKVLSTLFAMAFADKAGRRVLLMAGCIVMALSVTVIGLTSCSIPIEVVKDCEALVGSSNSSFSPGHLPIKSTSSEPLPSYFPLASGASEIPVESTFALTGSAAVQTHPSSENGKRITTVPSHTEQTYLFNHSFEEKRPGPSSSISEAPLKYHILLNWITLLSLMAFVSAFSIGFGPMTWLVLSEIYPTNIRGRAFAFCNTFNWAANLLISFSFLDLIDAIGLSWTFLLYGVVGVVAILFIYLFVPETKGQSLEEIDKQFSKKRLHQGNTCWQNMWKRSEILARAQYQRVDHSSDS
The following text describes a protein:
Function:
Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
Subcellular Localization:
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Sequence:
MESRIWCLVVCVNLCIVCLGAAVSSSSTRGTSATHSHHSSHTTSAAHSRSGSVSQRVTSSQTVSHGVNETIYNTTLKYGDVVGVNTTKYPYRVCSMAQGTDLIRFERNIVCTSMKPINEDLDEGIMVVYKRNIVAHTFKVRVYQKVLTFRRSYAYIHTTYLLGSNTEYVAPPMWEIHHINSHSQCYSSYSRVIAGTVFVAYHRDSYENKTMQLMPDDYSNTHSTRYVTVKDQWHSRGSTWLYRETCNLNCMVTITTARSKYPYHFFATSTGDVVDISPFYNGTNRNASYFGENADKFFIFPNYTIVSDFGRPNSALETHRLVAFLERADSVISWDIQDEKNVTCQLTFWEASERTIRSEAEDSYHFSSAKMTATFLSKKQEVNMSDSALDCVRDEAINKLQQIFNTSYNQTYEKYGNVSVFETTGGLVVFWQGIKQKSLVELERLANRSSLNLTHNRTKRSTDGNNATHLSNMESVHNLVYAQLQFTYDTLRGYINRALAQIAEAWCVDQRRTLEVFKELSKINPSAILSAIYNKPIAARFMGDVLGLASCVTINQTSVKVLRDMNVKESPGRCYSRPVVIFNFANSSYVQYGQLGEDNEILLGNHRTEECQLPSLKIFIAGNSAYEYVDYLFKRMIDLSSISTVDSMIALDIDPLENTDFRVLELYSQKELRSSNVFDLEEIMREFNSYKQRVKYVEDKVVDPLPPYLKGLDDLMSGLGAAGKAVGVAIGAVGGAVASVVEGVATFLKNPFGAFTIILVAIAVVIITYLIYTRQRRLCTQPLQNLFPYLVSADGTTVTSGSTKDTSLQAPPSYEESVYNSGRKGPGPPSSDASTAAPPYTNEQAYQMLLALARLDAEQRAQQNGTDSLDGRTGTQDKGQKPNLLDRLRHRKNGYRHLKDSDEEENV
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MPPGEPVGSSAQGERDFISKWLHQTLKASDWYVKPIVNFDGDKSDMDEVYKAVKFWRDLALELKSKNYPLAEGIDNYQSFDEETRKKAHMLDDFLDGFIDEELQEDEKTFEILRVLIAQGEPYMEFKQKMKENDFSLKCNEIWENDAVAFRCNTCALTPCMSLCEDCFESNGHAGHDYTRFFSREGGACDCGNQDVIKEQGNCKNHGDESKRPNYDMSEVCLAEYIVMKLIVRLFLEYRGWASRYEKALDEFKSESNEPINRRAVFDIGEFTVDDAARSDYLITFLQECVKYGGPMRLIVSKILLDKNLYKVLTEQTSEHYDASNRVQISLDWRTAHMFKDDRRTVLPPDNSNFSFVGSIESTECTSLLDELIFWINRQLFPQNLVNFGLSLLSEPGYRDAFAYRFFSWYPISGKVISDLCISQAGHSRAQDLVTPACSRAVHVTVQMLSSASLCKELNENVHLVKTIFDVTRFLICEKSVDSEISLKSVNIFKESSRFLNMTTTNGRPKWRVMTMANNAAISQHGYWFVMGDIQNVLTHTSQAIAAVFDDECFGGSYMKMMCEMQGMNPIWRIISGNAQENDAGEGAQRAYTLEFETLAVTLFNIVAAIQQEKDVRTACRFFDHIRSQLEEWFHVLLPVTPEDRSEVWGNVIRAQAYAVSFHIPLHRHISTAITHFTELDGFYDHIRSNLLNDETLIRLLLVHPLRIQVARAEINCNMWVRNGAQAKMSALIYSQWNVSSAFQTPDVDLIRFCAAHIDKEHFMKALTASFNITECIKIQRGRFVEKSEESKILFQGVGGRDDDEVSEARKTEFERYQRLVREQALLMEDMMLTPEKNLFQFDEKETDEAVDVMIEANNATEVTIDFTIQSPIDHSRDPRIPIVGEFIRRHLEAAGVDADIDVEMEREFDPRLFDDEEVERTIVIREPEWIDPMFWGMFKLVAELVVVRVNSGASPEEHYRSEMVNCMAMGNVPYSRLRASISEKGSRGSEMIDKHFETILNEIGDFIEPIETTTHLMQGSYQLKTSIWDSEVCPVFFMMRSTSIKQAREVFAKMEIREQKNALDKDLEVAKIEERFWVPFRLIDFSDQKRHRGISNLYNVLLTERFLIHCITVLASEADETAKFHDGTYQLAVYLLTLGVKYAQSYVGDEKIKKQMIDIFHTPFQLIKFREMETFLTVCAFMIRLLTKETRKNGALVVVFKGILSGEYDKEKVTGGKMIYLARFVTILTKLSPVARQIIEGKLKREELRISKHSRNQEKMKAPMDPVKKAAKEAAKRRMEAIMQNSAKKSAQTMEKLMKTEGMTDAEVNKVDPSQQNRKVYECPICGEQNAPNTVENPFGMLAKLSTNFICEEQIDASINTIDDLLKFDEYEHVSANRLQSETRRRFFSKRRQATFENQDIVKVNPPLVGTDLKTCGHAAHIACFNAYRASLYDGHQRSTDRREVGCPMCRYTVNVIVPMSFDKPYTPIKTPASPMSYSDVWRVMDVVLKKAKGPVFQEDERNVKYSTNYSTREGGGLFELYIGRIHSADLAERKSSQQRCTVSTLMVSLAVVMVERSSIMRKMGVPERRKNQRNSMTEHLMTASVATSKDVDFDVALSALTNLFAKVTENSFSRPPSEQPSTSKEPAQGTEAPNPEAVVGLSSDEMAAMITKPLRKDTPDCLSKLPLFALDPKATLVRMLAVLIDNQSLTKDIQREIAQNMIFASLGWVSSYTLLCLILRTGEEKISALNKGEPKIQGLSDHLQSEAEAICQALTYNTEYFKHLAQRLESPDVEPTDEYICKTMNSCLIEFLRFSYELLFHCNLGFNDVNNQIHSRNIDLDNVLRLVGINAQNINVPGKANYWTRAFRTQLTNMAKLKRIFQPCIVEPLAWKPRRILKPPTNFDELFGRYFHRECNKCSSVPSYPVMCLFCGEILCLNDCCRMAHQESGSDRVISMSEIEAHAEDCSSSSGLFLSVTSSMVVVSRGKQAAIWGTIYLDAHKEEDRNLKRGKPLFLCESRLKWLEYDWAEQEWQRVPQWFNMTNSQAFTSNIRDCHLFQR
The following text describes a protein:
Function:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MNVTTDTYGQAASNLVAGSSLEQTIQQIMDLGGGSWDRDTVSRALRAAYNNPKRAVDYLYSRIPEAAEIAVPAAPYPISQTTETGGVTAGAVSGFQALRSMVQSNPQILQPVLQELGKQNLSLSRLIQEHHGEFLQLINDPVEGSEGDIFDQPEQDMPHAINVTPAEQEAIGRLEAMGFDRASVIEACDRDEQLAANYLLENAGDFED
The following text describes a protein:
Function:
Core replisome component that acts as a replication initiation factor. Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork.
Subcellular Localization:
Nucleus, nucleoplasm.
Sequence:
MPCERKPMRYGHSEGHTDVCFDDQGKCIVTCGSDGDVRIWESLDDDDPKSINVGEKVYSVALKNGKLVTAVSNNTVQIHTFPDGEPDGILTRFTTNANHVTFNNSGSRVAAGSSDFLVKMVEVADSSQQKTLRGHDAPVLSVALDPSDEFLASSSCDGSVAVWSIESQTQVAQWKVLQKSSDVTNAKSLCRLAWQPRSGKLIAVPVDLTIQLYERNTWTHVSTLSDDLITQVVNVVVWSPCGKFLAAGTVGGNLLIWDVEAKLCIDRQKHEKGFTVCGMAWHPSGGRIAYTDTEGCLGLLEGVSSSSSTVQSSKATAAKEANDYDDLFDEDDDRMLDEDMSDSRSPVKKPIMEDEDDDDDDDLMPATGRPRNRGSFLDDDDNSQDPSSVKLDGLPEEGGSSAVLPAVAPVVSRPVYDGPMPTQPQRAFQPGSTPAHLMHRFMMWNSVGIVRGYNDDQDNAIDVEFHDTAIHHAMHLTNTLGHTMADLSQEAVLLACEGTDELASKIQCLHFSCWDTHKDWMVDLPKGEDVRALCLGQGWAAVATSALMVRLFSIGGVQKEIFSLPGAVVCMAGHGEQLLIAYHRGTGFDGEQALGVQLLQLGRKKRQVIHGEPLPLSRKSYLAWMGFSAEGTPCCVDSEGVVRLLNRTLGNTWTPVCNTRETCKSKSDHYWVVGVHENPQQLRCIPCKGARFPPTLPRPAVAVLPFNMPYCQTTTEKGQMEEQYWRSMLFHNHYGFLSSSGYEIDSESQAQAEKEQQELLMKMFALSCKLEREFRCVELAELMTHSVVTLAIRYASRSRRMALAQRLSELALEKANQLQEEEQEDEEPAYQSREYRESNQMNSRQAQQENGCEEEEVEEEEYPQEEQMDAEESTETRKKFLNPFKKGGKSPEKPSPKPVSREGRVNPFKVSGAGKSSGSPAGQPRTTNVLDSMTMSRKPAAFSGLSKQSKAPVLKPLAPKPKSKTQATLLQMSASKGNSKKLEDSQSEAEKVKPAPVAATPPVLKENTENKKPKTGFQLWLEENRKSILADNPDFEEMDVIKEGMGRFRTLSAEERLNWTEKAKGDSDPKKRKREDEDEEKAAEQMESDEASAKKKKPLDSSAKLSAFAFNKE