lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MKLNVKTLKGTSFEIEATPESSVGEVKRIIESAQGQNVYPADQLMIIYQGKILKDDTTLDANKVAENSFLVIMLSKPKASSSGASSASKAPVSQSQPATPVAAATPPVPVASAARSPPSQAPVAASEPAPPSAQPSAVSDTPAAAVTASGDADVYSQAASNLVSGGILEQTVQQILDMGGGTWERDMVVRALRAAYNNPERAIDYLYSGIPESVEAPPVARAPAPAQQAQNLQAPSQAQAAPLPAVQPSGGVSAGPNANPLNLFPQGVPSGGANAGAGVGAGAGALDALRQLPQFQALLALVQANPQILQPMLQELGKQNPQILRLIQENQAEFLRLVNETPESGAGGNILGALAAQMPQAVQVTPEEREAIQRLESMGFNRELVLEVFFACNRDEELAANYLLDHGHEFEEQQ
The following text describes a protein:
Function:
Effector of the TORC2- and calcineurin-signaling pathways (By similarity). Mediates actin polarization via inhibition of calcineurin-dependent transcription (By similarity). May play a role in the response to the disruption of sphingolipid synthesis, where dephosphorylation of slm1 leads to the activation and phosphorylation of ypk1 through the TORC2 and PKH1 pathways, which in turn phosphorylates orm1 and lag1 to activate sphingolipid synthesis (By similarity).
Subcellular Localization:
Cell tip.
Sequence:
MELSGKSEFPTRTEIPNQASNGDAVPNTDAYMGLCNSLTYRFEGWRHLVENLIAFFKQLESTSKNNAKEYMKLSKVIVHPYKDANVFEEHGIQDIFAALRDQTAAIASDSEQISIQLPGTIINILELLREDLREHCKKIAAEGTKGVKVVEKQRAETQKYLSLLDRALLPWRASSPPTVNIKNDPFIVDRQVLNCLARQVQEENNHSVAVAQLQEFSFRFEQNLIAKIKDTVKQFEGMMNQTHVKAINHLQEVVRVSEAQTLAGEWTGYAKREPEFIHGSVPPRSVDAIKYPGKNDQPTVPIMAGYLIRKTSFLKKKQRGFYAFTHSGYLYEFKSSDSLQDPEPEFALYIPDCLIGRPSEKKPKFKITGKDATKKIFGARNDYAFRASNNTELMRWWEALNTHIANVNYIQPLSNANGPSAVSDSDDDDDDPNDFRPAVERQSSTMNTRMSQPSSAVNTNRSYGSEQIPSYADSQGNSGANNNFIYNASATGHNAWNV
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Sequence:
MSLEGFAELRAQMEAFQGRVHGHLGQQRHAMEQLLAAHRQEVEKLRLRTGAVQQQLARLAGEEQELRQNISSLQERTQHTTAQRDAYAAQRQKLAAERTQLEHDRAELHAMLARKQAELQRQREAIKRQHMRDNPEVRVYEQLLGLYVRASRPDSLEFAFRNVSEADARAECSFTLDLGADGYRVAAAQPPLPLERLRDLERDLGSSGDLPAFLKAIRAALVTAMAGQADA
The following text describes a protein:
Function:
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Membrane; Peripheral membrane protein. Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes at the cell tip and the barrier septum. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex (By similarity).
Sequence:
MSTIEAIYLVDTNGALLLQLESRGRTSPITLEHIKNELFRYKLRNEEPPFILHNKNFLIFQELEEDVRLCIPTTCDTEPLYIHDIMRRIVDVVKTFFGGFNASKVEKNVCVIVQLLAEMIDYGYATCMEPNALQDIVPLPSFMNKFMAVTGLQTNTPTLARDTVPWRTAKAKYATNEFFIHVLERVSAVYQPNGKLAFGTVKSDMECKCQISGMPLLLLSLRPGTKLGNVRFHQSVNLKRWKQHPDQIEFIPPDGKFTLASFQTDFATQKSLPVVVEAKNKLDGRFEVRIRNTGKKSVENLKILITIPQALKSVTVTEGNYIFRASKYTHMEEGILEWSVKKLAWTSPALVLTGFLAPLKKDANSTEESSSYSKLEHLDLQYKLQGSTLHNFKVESLKMLNHPDKKSYKGVKHTIIAQNVSFRFR
The following text describes a protein:
Function:
Calcium-independent phospholipase, lysophospholipase and O-acyltransferase involved in phospholipid remodeling with implications in endoplasmic reticulum membrane homeostasis and lipid droplet biogenesis. Preferentially hydrolyzes the ester bond of the fatty acyl group attached at the sn-2 position of phospholipids with choline and ethanolamine head groups, producing lysophospholipids that are used in deacylation-reacylation cycles. Transfers the sn-1 fatty acyl from one lysophospholipid molecule to the sn-2 position of another lysophospholipid to form diacyl, alkylacyl and alkenylacyl glycerophospholipids. Cleaves ester bonds but not alkyl or alkenyl ether bonds at sn-1 position of lysophospholipids. Catalyzes sn-2 fatty acyl transfer from phospholipids to the sn-2 position of 1-O-alkyl or 1-O-alkenyl lysophospholipids with lower efficiency. In response to dietary fatty acids, may play a role in the formation of nascent lipid droplets from the endoplasmic reticulum likely by regulating the phospholipid composition of these organelles; (Microbial infection) May play a role in replication and assembly of human hepatitis C virus (HCV). In response to HCV infection, promotes remodeling of host endoplasmic reticulum membranes to form organelle-like structures called membranous web, where HCV replication occur. Can further mediate translocation of replication complexes to lipid droplets to enable virion assembly; (Microbial infection) May facilitate human T-lymphotropic virus type 1 (HTLV-1) infection by promoting leukotriene B4 (LTB4) biosynthesis. LTB4 acts as a chemoattractant for HTLV-1-infected CD4-positive T cells and favors cell to cell viral transmission.
Subcellular Localization:
Cell membrane; Lipid-anchor. Endoplasmic reticulum membrane; Lipid-anchor. Mitochondrion membrane; Lipid-anchor. Lipid droplet. Note=Translocates from endoplasmic reticulum to lipid droplets in response to oleate.
Sequence:
MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAGLYYPKDSARSCCLA
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MEFRNLDGDLGLPPPSSPSSSPLVYNPPPIRGSAFSKPILPLSSSLIPSRGGGGCCDTAATGGERNGASFGSSTIPTATEENSSSHSNTRNPDPAPISVLSPVGAGASLPNSIQSAEVKTAVTTVDASVKYKECLRNHAAAIGGHVLDGCGEFMPEGGPSTPEALKCAACGCHRSFHRKDGDTDVNADNSYHHHHHGASHLPLLLPPPHPQSHPYNQQKPFPFGFPSSPPSRAVPLSSAVMAFGGNTCGSGGTTTESSSEERINAGAPTPAIALRKRFRTKFTAEQKEKMLAFAERVGWRIQKQEEAVVEQFCAEVGVRRQVLKVWMHNNKHANTKQQQLQPPPPPVEQDQLQVQQHQEQQ
The following text describes a protein:
Function:
Required for defense against powdery mildew pathogen.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MTFLPLLFIFFFLTSIPFPAFSQYNDRSTLLNLKRDLGDPLSLRLWNDTSSPCNWPRITCTAGNVTEINFQNQNFTGTVPTTICNFPNLKSLNLSFNYFAGEFPTVLYNCTKLQYLDLSQNLFNGSLPDDINRLAPKLKYLDLAANSFAGDIPKNIGRISKLKVLNLYMSEYDGTFPSEIGDLSELEELQLALNDKFTPVKLPTEFGKLKKLKYMWLEEMNLIGEISAVVFENMTDLKHVDLSVNNLTGRIPDVLFGLKNLTELYLFANDLTGEIPKSISAKNLVHLDLSANNLNGSIPESIGNLTNLELLYLFVNELTGEIPRAIGKLPELKELKLFTNKLTGEIPAEIGFISKLERFEVSENQLTGKLPENLCHGGKLQSVIVYSNNLTGEIPESLGDCETLSSVLLQNNGFSGSVTISNNTRSNNNFTGKIPSFICELHSLILLDLSTNKFNGSIPRCIANLSTLEVLNLGKNHLSGSIPENISTSVKSIDIGHNQLAGKLPRSLVRISSLEVLNVESNKINDTFPFWLDSMQQLQVLVLRSNAFHGSINQNGFSKLRIIDISGNHFNGTLPLDFFVNWTAMFSLGKIEDQYMGTNYMRTNYYSDSIVVMIKGIALEMVRILNTFTTIDFSGNKFEGEIPRSVGLLKELHVLNLSNNGFTGHIPSSMGNLIELESLDVSQNKLSGEIPPELGKLSYLAYMNFSQNQFVGLVPGGTQFQTQPCSSFADNPRLFGLSLERVCVDIHKKTPQQSEMPEPEEDEEEVMNWTAAAIGSIPGISIGLTMGYILVSYKPEWLMNSGRNKRRIKPI
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Sequence:
MSPLMTAMIDVTDAKKTFTMHLQGGIELPVVSGVTFQVNPGECVVLSGPSGAGKSSILKMIFGNYRCDSGRIGIRHRGALIDLATAEPRQVLNVRRATIGYVSQFLRAVPRVATIDVVAEPLIVNGMARTEAQQRAGALLHRLNIPERLWQLPPATFSGGEQQRVNIARGFISDLPILLLDEPTASLDAANRAVVVELIAEKKRQGVAMVAIVHDDEIRHLIADRIVDVTSFAAAA
The following text describes a protein:
Function:
Anthrone oxygenase; part of the gene cluster that mediates the biosynthesis of endocrocin, a simple anthraquinone interesting for many biotechnological applications. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) encA. The atrochrysone carboxyl ACP thioesterase encB then breaks the thioester bond and releases the atrochrysone carboxylic acid from encA. The atrochrysone carboxylic acid is then converted to endocrocin anthrone which is further oxidized into endocrocin by the anthrone oxygenase encC. The exact function of encD has not been identified yet, but it negatively regulates endocrocin production, likely through the modification of endocrocin itself.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MASVQGLIKIVAITGGVWLSGKITAHSLVSVPALLQTRSADGLSPCTILRVWRRIYEQGHRHSPQIAACTSTAFAYLAWCASDRTPRLLYGTAACSVMGIVPYTLLFMGPTNSRLLERSAAEEEKVPGATRGEDMVNVPSEMTTEELLSHWRFLAGIRGLLPLAGGILGLFAALYSNEGAR
The following text describes a protein:
Function:
As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores. Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus, nuclear pore complex. Nucleus, nucleoplasm.
Sequence:
MSRPPNPNPPNPFGSPGQWVPGQPSPPFGAPAEASPATAALTPAFGGDASQPGAGMGPTGPGARSSFGLQSLLLGAGRGTQPFPARPEAEGVASAASPSQRMSADTPVPTPGESTEPDAVTPEPEGREGGPRAMVRRLGRSPSASQRLPARAAGSAEKRSSGGTKVMATPEEIGQLTTVLCNGLPAELNDREALLEHFGQFGRVARITCNPRKGCATVRFEDHQSAELAKKRGARISDRCAPLQIFWCSKRRPSSDAGTGPARTGGRNEGGAPPPTRPQTRDSTPDDFVELRTPEEQAAESQTPAPSAPAPAAAPAATLASTLARRAASRLTKVAPRKARAALGRESDGGTTALGEESLAGLLTQAAHSVGERYRVLDARDKIIRLRSQRQSDLATARATRGSCPDMCPEKERYSRTHRKLLSSFEVLPGSDGVMDPSRMVKEYSRSSADQEEPLPHELRPPHVLRLTMDYLLVHVMDPPHPPPVGEWYDFIWNRTRSIRKDLTQQHLCEPSCVSLVEQCARFHIHCASALCEEDVSVFDPRINGENLAKCLQTLKHLYYDLGLRGLRCPNEPEFRAYDVLLHLDQADTVRQVQALDAWVRRSAPVCLAVSALGALSSGNWVRFFRLVGVAPYLSACLLHRYFGRVRLQAFHTLLRAFCQTSHREEQFSLESLGRQLGFDSPSEVRAYARALGLGCSEDALLLDRSSQIQTESGGPPAGRSRRLVDAKCTCSVGEVVNGGPLPLDPTADYRPHDSFSLDGVLRGMAYDARDQAGKCWPSEEAEPGEEPGLIGGPQEPEPPPQEPPPPEVPIEVVRDVARDLLDEAVQEHVEGLGRDFLLGQVAHATVASLVAEETCKMAKECCQEAFLGAEEQRLQELLLAKQRDRERRLGAQEAIAGELIEEVLMDAARQACRSCHREAQERLWEEQGTALLGQLVREVAEEEAALAAAQVLAREQALHEAATRLADTCRRRHLLGTCFARWVEHCEAERWRRLARETFPACPSLGLDPRNPAFGPSRKRARLSDDVFRGLEASLALRLLSEELDWAPLDLSREWGHPSKLVVYLPEGDPGNAREALARVQARLGCRPSPDAQVETLGGSRWSVSVVRGPLSAGGLDHAGRPRLLRGASAVLFVAAGKSAGPRLRELLCWASVLRPVPCVCVLDLCGSQEERSALGETLALCSAERLLPEACRVLSTDDRPCRTLGRTVQEAVRWCSESRVALPQLQTSRLGDFVEQGVSRMVFDVAYAALPDFQGDWQLPTRLVDLYNAVLRHLAAVAASSSLSDMSVEVQDGCDWSAPDRLEALQEAVLGLLLPAPGADLWKTSAVWDYLELLCGSNGPRGTAALLFAREACSSCTLALLVKSPNIRAAFKEKIHSAITGGNEKATAAQPFLLYGNYEESVGGGEAVGGAEPEVPWDLERLVARQRALSRSLTSRLEALLAPPLSTAPKGKLPFRRPLSAGGDFALPDVRCLERGEVCVRPEGHQDVEALVAAAEEELQARRRSSALLQALLVTALDS
The following text describes a protein:
Function:
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
TCLAHKQQAVNRLLYRIYSPIXXXF
The following text describes a protein:
Function:
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. In particular, may act redundantly with the intraflagellar transport protein ift-43 to regulate the transport of specific ciliary cargo proteins such as che-3 which are related to motility. Functions in cilia biogenesis.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, dendrite.
Sequence:
MDSESDDNPNDPEDRKKWGHKDVEHWRAVSNVHYYAREGYFGTAILVCDGRLATIKDPALAILKGVCLTLLGKIPDAIRHLETFVTDNDVALGALHALKWAHASAFNPDNKSIVEIETEISTRARNEKTPYTSYATASEVLYFAGEYQKSKQMLDIARKRATEKHAKHYCLLGWIELALGKKQKSTQELFEKAGGQEYPDGNIGRCKILEGHHSAPEMKVAANELAISTIHFLPGHIEKAKASIMMKDWRGVMDCIMNADQPEGSNPYIEVLRTVHGICYAGEVSMLKRTLQLLLKSLDENEATNHVLYARITKLLVSISGRDEKILRHARDFLTRALKISRKPDYVALSMRIAFGLGGAKEVSTLSQELVALDCEDSYAVLSSVVSMLMISRVSDARAQFDILPSAHPKLLESPLYYLIASVLAKQSKDKSFENFRQHIENLVEMLRNQLQSFPFGLDYLSLFSSDLLYSAVEQCFDFYPLVPIKAPDDCMKLTAKTLQMIYDVAPGLAHCTLQLARNSYLCSNTNAAEKWIEKVLDKDDSLADAHILRAELILDRGGKITDADDALVTGLNFNFKLRETSLYHLIKSKTFKKRNENDEAIKTLKMALQIPRKEPSKNLFQPKESADTHKISVQLELIDTLQHMKRIQEAETTMTDALAEWAGQPEQDQLVIAQAQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMAEIYLEEKKDKRMFAACYRELLKVEATPGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKDKNMRLKLANLLLKLRNFEKCEKVLRAPFERDPEPVGTETIQTYIQFLLLLAECHEMMDNVPEAMNDFEKAKSLHSRIQDKTLTAALKKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNPRCVTESGYNVCRGRFEWYTGDQNEALRYYSRTKDSAAGWREKALYYMIDICLNPDNEIIIDENSVENPETTIVEEASEQQKLAKYYLDLLGKLPTTDRFLLAQNFIRMHTTDKSAIQAALDEFNRMAFNADRSQVTNVGAVFGVARGHVLLKQVQKAKTVLKMVNGRVWNFDDSDYLEKCWLMLADIYINQNKNDQAVTFLDLVFKYNCNCLKAFELYGYMREKEQKYVEAYKMYEKAFMATKERNPGFGYKLAFTYLKAKRLFACIETCQKVLDLNPQYPKIKKEIMDKAKALIRT
The following text describes a protein:
Function:
Involved in endosomal protein transport.
Subcellular Localization:
Endosome membrane; Multi-pass membrane protein.
Sequence:
MGGVRAVAALAFAGVVGLTFLVLGCALPRYGTWTPMFVITFYVLSPVPLLIARRFQEDMTGTNACIELALFITTGIVISAFALPIVLAHAGTIANSACFLVNTGSVIMFGTIIAYFYLHRDDDSGSWSQSLF
The following text describes a protein:
Function:
GTPase possibly involved in regulation of the MEK/ERK pathway.
Subcellular Localization:
Nucleus.
Sequence:
MDTNVQKRRENKKSLRVKVISLGNAEVGKSCIIKRYCEKRFVPKYLATIGIDYGVTKVQVRDREIKVNIFDMAGHPFFYEVRNEFYKDSQGVILVYDVGLRESFDALDSWLTEMKQEMGSQANMENIIFVVCANKVDLTKRRVVDESEGRLWAESRGFHYFETSAQSGEGINEMFQSFFSSITDMCENGGKRPTPEVSVGFTKEQADTIRRIRNSKDSWDMLGVKPGATREEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTSLLKNIK
The following text describes a protein:
Function:
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.
Miscellaneous:
MISCELLANEOUS: The atypical heteromeric and topological design of the odorant receptors appears to be an insect-specific solution for odor recognition, making the OR/Orco complex an attractive target for the development of highly selective insect repellents to disrupt olfactory-mediated host-seeking behaviors of insect disease vectors. Odor-evoked OR currents are independent of known G-protein-coupled second messenger pathways.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEKQEDFKLNTHSAVYYHWRVWELTGLMRPPGVSSLLYVVYSITVNLVVTVLFPLSLLARLLFTTNMAGLCENLTITITDIVANLKFANVYMVRKQLHEIRSLLRLMDARARLVGDPEEISALRKEVNIAQGTFRTFASIFVFGTTLSCVRVVVRPDRELLYPAWFGVDWMHSTRNYVLINIYQLFGLIVQAIQNCASDSYPPAFLCLLTGHMRALELRVRRIGCRTEKSNKGQTYEAWREEVYQELIECIRDLARVHRLREIIQRVLSVPCMAQFVCSAAVQCTVAMHFLYVADDHDHTAMIISIVFFSAVTLEVFVICYFGDRMRTQSEALCDAFYDCNWIEQLPKFKRELLFTLARTQRPSLIYAGNYIALSLETFEQVMRFTYSVFTLLLRAK
The following text describes a protein:
Function:
Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVATLQLISPLFLPPPQQVLEKLLTIAGPQGFMDATLWQHLAASLTRIMLALFAAVLFGIPVGIAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSVQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
The following text describes a protein:
Function:
Dual specificity protein phosphatase which dephosphorylates both phosphotyrosine and phosphoserine residues.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Localizes to the cytoplasm at the ring stage, translocates to the nucleus in the trophozoite stage and returns to the cytoplasm at the schizont stage.
Sequence:
MIVKVFDYIYISNVYNANDIYELIKLNIGGVLTCFDCTCIEWCHHNDTNVTNKIFYKDIFVNTKKDLIKCDVPIITNKSVNSDIIGGTHQINNYYNEQNNNYHDNTYKEFTQTHKTNIDPSQIKSDHINEERKEHYDYIIFPSDIINNTQCNNNNLKDYIKSMLILKEDAYIDFDVIHMDQLKNKHNNNNNNNNNNNNNNNNNNNNNNCCTFKNPDISNTSQHHVEHIQIHKSNSHSNIPSDNINFCNKKYDKNLSRSVEISEKDKHPENSLLYEFVNKDKLNYKINQEEDTVSSEKNKLCDNNNNNNMVHTRHIYNVCELNKCLRENKLIPYNNIYKMKHLYLNILDTFDENILKHVNKAHLFIDSVIQKKKNILIHCMAGISRCSSIILSYVSKKNKKGIEYNFNLLKSKYPFAHPNENFYRQLLLYEKMNYTLDGCTDYHNIYKKIKMNRENLEELKILNLKNDKQPIYNFRCKHCNYVLFNDNEIIKHDFKISKIKKNYGNSCTSIFIEKKEWILTENKMKGVLNCPNVNCNIKLGKWSWTGICCSCGYLQIPAFMINSSNVDRMNISKTV
The following text describes a protein:
Function:
Non-structural protein implicated with protein sigma-NS in forming the matrix of viral factories, which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Together with mu-2, recruits the other core proteins to these factories.
Miscellaneous:
MISCELLANEOUS: [Isoform mu-NSC]: It is unsure whether Met-41 is the initiator.
Subcellular Localization:
Host cytoplasm. Note=Localizes to the viral factories formed by mu-NS and sigma-NS. Localizes to the host stress granules (By similarity).
Domain:
The C-terminus is involved in the formation of factory-like inclusions.
Sequence:
MASFKGFSVNTVPVSKAKRDISSLAATPGIRSQPFTPSVDMSQSREFLTKAIEQGSMSIPYQHVNVPKVDRKVVSLVVRPFSSGAFSISGVISPAHAYLLDCLPQLEQAMAFVASPESFQASDVAKRFAIKPGMSLQDAITAFINFVSAMLKMTVTRQNFDVIVAEIERLASTSVSVRTEEAKVADEELMLFGLDHRGPQQLDISNAKGIMKAADIQATHDVHLAPGVGNIDPEIYNEGRFMFMQHKPLAADQSYFTLETADYFKIYPTYDEHDSRMADQKQSGLILCTKDEVLAEQTIFKLDAPDDKTVHLLDRDDDHVVARFTKVFIEDVAPGHHAAQRSGQRSVLDDLYANTQVVSITSAALKWVVKHGVSDGIVNRKNVKVCVGFDPLYTLSTHNGVSLCALLMDEKLSVLNSACRMTLRSLMKTGRDADAHRAFQRVLSQGYASLMCYYHPSRKLAYGEVLFLERSSDMVDGIKLQLDASRQCHECPVLQQKVVELEKQIIMQKSIQSDPTPMALQPLLSQLRELSSEVTRLQMELSRTQSLNAQLEADAKSAQACSLDMYLRHHTCINGHTKEDELLDAVRVAPDVRKEIMEKRGEVRRGWCERISKEAAAKCQTVIDDLTQMNGKQAREITELRESAENYEKQIAELVGTITQNQMTYQQELQALVAKNVELDTMNQRQAKSLRITPSLLSATPIDSVDGAADLIDFSVPTDEL
The following text describes a protein:
Function:
Serine/threonine protein kinase that specifically phosphorylates chloroplast precursor proteins in the cytosol within the cleavable presequences (transit peptides). May be part of a cytosolic regulatory network involved in chloroplast protein import. Does not phosphorylate mitochondrion precursor proteins. Specific for ATP and does not utilize other NTPs. Plays a role in chloroplast biogenesis and differentiation in cotyledons, possibly through phosphorylation of chloroplast preproteins.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MVMEDNESCASRVIFDALPTSQATMDRRERIKMEVFDEVLRRLRQSDIEDAHLPGFEDDLWNHFNRLPARYALDVNVERAEDVLMHKRLLHSAYDPQNRPAIEVHLVQVQPAGISADLDSTSNDAGHSSPTRKSIHPPPAFGSSPNLEALALAASLSQDEDADNSVHNNSLYSRPLHEITFSTEDKPKLLFQLTALLAELGLNIQEAHAFSTTDGYSLDVFVVDGWPYEETERLRISLEKEAAKIELQSQSWPMQQSFSPEKENGQTGARTHVPIPNDGTDVWEINLKHLKFGHKIASGSYGDLYKGTYCSQEVAIKVLKPERLDSDLEKEFAQEVFIMRKVRHKNVVQFIGACTKPPHLCIVTEFMPGGSVYDYLHKQKGVFKLPTLFKVAIDICKGMSYLHQNNIIHRDLKAANLLMDENEVVKVADFGVARVKAQTGVMTAETGTYRWMAPEVIEHKPYDHKADVFSYGIVLWELLTGKLPYEYMTPLQAAVGVVQKGLRPTIPKNTHPKLAELLERLWEHDSTQRPDFSEIIEQLQEIAKEVGEEGEEKKKSSTGLGGGIFAALRRSTTHH
The following text describes a protein:
Function:
Acts as a suppressor of ciliogenesis, specifically, the initiation of ciliogenesis.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes to centrioles in proliferative cells and basal bodies in ciliated cells. Disappears during ciliogenesis but reappears, albeit at a lower levels once ciliogenesis has completed.
Sequence:
MEETANDGSHSEELFSHFESRSEKEGLPQDASESHLSCLKQDIQNEKTELEALFKEAELATCSAELLLPLFKDTIEEISFENRGESLSNLLEKLTDNERENINLKNKVLEKETYIQELSSLFQNEKANALKASRFSQSVKVVHERLQSQIHKKEAENEKLKEHIKSLETQISEWNLQLKKNKYEAVAMKESSRQKTIALKKASKIYKQRIEHFTGDMENLTSQIREQEAKLSETVSASNAWKSHYEKIVIEKTELEVQIETMKKQIINLLEDLKKMEEHGKISCEEILRKLHSIEYENETLNLENTKLKTTLATLKDEIASVENELLELQEVEKQQKTLIEVYKTQIQKVQEAAEMVKSRCKNLLQENSLITKNKNKKLKKVDENHSLLTKLSLEEENYLIQLKCENLKQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAEYTALARQLEAALEEGRQKVSEEIEKMSSRERALQVKIVDLENELRKKNEEQNQLVCKMNSKAQHQEVCLKEIQHSLEKSENQNESIKNYLQFLKTSYVTMFG
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MATGFPGRGGRVEIQDSNDVLSLCQMKKMICNDHDIEPWTMSPAYAQICNVLQQLAEAVKSKPRSHQHVVNPIIGKILDTFKILHQYLIEIEPLKTPMRFGNRAYRTWLTKVYDNRKEILKEISDNPDVWDYYCQSFGSWTRIDYGTGHEFNFLAFIASLFALGIVQPEDSEAIVFDVFWAYWDLVVAVQERYHQEPAGSHGSWGLDDYVFLPFLFGASQLIDHPEITPANVIDPVIAKAYVADYSYCKWIDYIYKVKKGAFAEHSRMLYSLRNVPHFTKLTGGMFKMYKGEVMDRFLVVQHFRFGEVLKWE
The following text describes a protein:
Function:
Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. Phosphorylates ODF2 on 'Ser-95'.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle.
Sequence:
MGKGNTLEAAPPTSAYRSVMEEYGYEVGKVIGNGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQMTLGIAYLHSKGIVHRLTPSLSAAGRDLKLENLLLDKRENVKISDFGFAKTVPSSQPVRSSPSYRQANCVTHLSQTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLKETQKEVTFPSNHTISQECKNLVLQMLCQATKRATILDIIKDPWVLKFQPEQPTNEIRLLEAMCQFPSTTNRQSLEIST
The following text describes a protein:
Function:
GTPase-activating protein for the ADP ribosylation factor family (Probable). During neurogenesis, involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell probably by controlling endocytosis. In oocytes, involved in vitellogenin vit-2 uptake by regulating receptor rme-2 endocytosis; [Isoform b]: During neurogenesis, involved in cell autonomous neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell probably by controlling endocytosis.
Domain:
The N-terminal domain is required for the positive control of neuroblast asymmetric divisions.
Sequence:
MPLIRNYDYYDLLNVAPSTSAHRPTVMVTSSRSYMEPQKSRIYYGKNEWRGGNTTIHDPTEFEETTMDKNANEIAGDDKRKKKRWRDLLFPNSRHSSRKDKENSNVSVATRSLSSVSFRSEKPSRRRESGSLSRHRYIPPPPLPMPPRRIMTSTSMGYSDDAMTSSSSHTTTDYDDIVPVPTPSYVIYPAASIAQASRRQQQGSAKNRIFRSPTYHHDAFVNSHEWTLSRSISEMKLGIVGTSQSGKTALVHRYLTGTYTPDESPEGGRFKKEVVIEGQSHLLLIRDEGQQHLDVQFCQWVDAVVFVFNVCSIQSYDSIQALAHEMSKYRNISDLPLILVGTKDHISEKRARVITEDEGRQLAAQMKRCSYFETSSTYGTNVERVFKEACCKIIQLRVRSQVGAAAAASSQARTPTPTHSESGGRKDYQDPSRYISSNSFVMPSNMRPSFPSNSTRRNTVHHRGEHPQQQQYQQQPPSSSRTASERSMSAMLGTPYGNRMPAGVSPSASQKSVHSIANGCYSRSSAALLDSDTPAVNSYLIDSMSSAGFPLSQSGANQVSASTSHLPTPSSTPNTQRKNRRISNIFRQKDHQEEKSKMIESLNLGIGRAIPIKQGNLYKKSSKSALNREWKKKYVCLYSDGRLTYHTNLKEYMDKTAHGKEMDLKLATIRITGRLHPLHSHRVASSVDPMNGGGGGGTPTLKSYEPRRSDVGANSGDGTSGGGSDDAIKENQRQHFSPPAMPQTVAGKKKRESRKIGTNSKHNDEEDECFEVINNCLMRWEFCAGSLEERDEWIQAIGGEIEKSLGKEVANAKTNNRAVANRPDIAALRSIPGNGRCADCGNPSSEWASINLGIIICIECSGIHRNLGSHISKVRGLELDQWPVEHLAVMQAIGNDKANEMWEFGLLNGERKPTPESSREEKERFIDRKYVQKAFLKPIASGEPVTSQLISAVLARDVMSLNVLLANGMSVEEINTTTKDGRTVLHLAASIGSVELAQLLIWHNADAQILDNNGRSCLFYARSNGFREVFDMLVTAGLSPDYGLPQEINDFSQMPEFFAMGSTSNRDYSTSGDEMYGSRRISMGPPPQVPARRYLPQQPELDETSVI
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MRLLMVIAILIFAMPMTGFGWAEGTNILLDPNLMCKKTRRLRGKLAEICRHDSALLKEIIINGINLGFRECEFQFRNRRWNCTVLRKSMRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRRNGGQPQMVTAATAEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHRGGRNRRPGGRRGRRKFWDNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKVTLRNDGNSFMPESPHARPANKYQLVFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVEEQTNCKCVFKWCCEVTCEKCLEHRAVNTCL