lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the inner chloroplast membrane translocon complex (TIC) which associates with the outer chloroplast membrane translocon complex (TOC) and forms a supercomplex involved in protein precursor import into the chloroplast stroma. Required for the import of HSP93, TIC40 and RBCS protein precursors in the chloroplast stroma. Links the outer and inner membrane translocons of the chloroplast envelope.
Subcellular Localization:
Plastid, chloroplast inner membrane; Single-pass membrane protein. Plastid, chloroplast intermembrane space.
Sequence:
MSLRLQNPFLSTPLLHGSFNRREKRINVARRAFRSKRIYSEKKQNDWLAKVAKFSQFCGKNVQLLRKSLDSRSRMEVKCLKEPFVRSKDLVRSLAPVWEEGLFFLRCSVFFAVISGVCLLVWYGQNKARVFVETKLLPSVCSVLSETIQREVDFGKVRRVSPLCITLEASSIGPHGEEFSCGEVPTMKVCVRPFASLRRGKIVVDAILSNPTVLVAQKKDFTWLGIPLSDTTLPSHLSSEEGIDFRTKTRRVSREEAGIRWDEERDNDARKAAEIGYIVPCKNYSQAKDNAVKHDRRFTEIANPNSFICMDEKMHSAEQHCMDPGVEYDVKHAELEKSFGIKIPGSGLKFLSKMLKVPRKYKFKWNSKSHKNSMSNISAKKRILERSASAALSYFHSLSQQKLDEPSVLSTNYDGLSLDMLLVKGDREISNQYDRHVPYGEQSLANDLDGKGYRVRGKRLLGVKKASTLDKFTVSCDPFLMTVDRLCALLQTKRSPSVEDIVNSSESETLSSQRGDISMNVVNQNTDDVPHGNRSGNQPRDFTFKKHEHQPVANHWRPSWPRNKKLKEAVFNILTGSSKKLTGRADPNAPHLSDELEKLPAVYVEKTLPVMLDSVQFKGGTLLLLAYGDTEPREMRNVHGHVKFQNHYGRVYVQLGGNCNMWRSDVTSEDGGLLSVDVFVDTVEQNWHANLNVANFFVPIFERILEIPIEWSKGRATGEVHLCMSRGESFPNLHGQLDVTGLGFHINDAPSSFSDVSASLSFRGQRIFLHNANGWFGKVPLEASGDFGIHPDEGEFHLMCQVPYVEINALMKTFKMKPLFFPLAGSVTAVFNCQGPLDAPVFVGSCMVSRKIAYLSPDLPTSLAYEAMLKNKEAGAVAAFDRVPFSYLSANFTFNTDNCVADLYGIRATLVDGGEIRGAGNAWICPEGEVDDTALDVNFSGNISFDKVLHRYMPEYFNIGMLKLGDLTGETKLSGALLKPRFDIKWAAPKADGSLTDARGDIVISHDNIIVNSSSVAFDLFTKLDTSYHDPCLSHQDFTQGEAMPFVVEGLDLDLRMRGFEFFSLVSSYPFDSPRPTHLKATGRIKFLGKIKRHSTTKDGDVGSDKCEDAAAISSLDGDISISSLKLNQLILAPQLSGRLSVSRDHVKLDAAGRPDESLTLDFIGPLQPNSDENVQSGKLLSFSLQKGQLRANACFQPQQSATLEIRNFPLDELELASLRGLIQKAEIQLNLQKRRGHGLLSVIRPKFSGVLGEALDVAVRWSGDVCFMLSGRLEVMITVEKTILEQSNSRYELQGEYVLPGSRDRDLGQKEAGSFLMRAMTGHLGSVISSMGRWRMRLEVPKAEVAEMLPLARLLSRSTDPAVHSRSKDLFIQSVQNLCLQAENLRDLLEEIRGYYTPPSEVVLEDLSLPGLAELKGHWHGSLDASGGGNGDTLAEFDFHGDDWEWGTYKTQRVLATGSYNNDDGLRLKEMLIQKGNATLHADGTLLGPKTNLHFAVLNFPVSLIPTLVEVVESSATDIVHSLRKLLSPIKGILHMEGDLRGSLEKPECDVQVRLLDGAVGGIDLGRAEVFASLTSNSRFLFNSNFEPFVQNGHVHIQGSVPVSFSQKNMSEGEVSETDRGGAVKIPSWAKEKEDDEKRTSRDRSEERWDSQLAESLKGLYWNILDAGEVRLEADIKDGGMTLLTAISPYANWLQGNADIRLQVGGTVDHPVLDGSASFHRASISSPVLRKPLTNFGGTLHVKSNRLCITSLESRVSRKGKLVVKGNLPLRSNEASAGDGIELKCEVLEVRAKNFLSCQVDTQLQITGSMLQPTISGNIKLSQGEAYLPHDKGGGAAPLNRLAANQYSIPGAAINQAVSSRYFARFFGTERASSGMKFSQSTGKSNSVEKEIEEVKMKPNMDIRLSDMKLVLGPELRIMYPLILNFAVSGELELDGMAHPKFIKPKGVLTFENGDVNLVATQVRLKREHLNVAKFEPEHGLDPLLDLALVGSEWQFRVQSRASNWQDKLVVTSTRSVEQDALSPSEAAKVFESQLAESILEGDGQLAFKKLATATLGTIMPRIEGKGEFGQARWRLVYAPQIPSLLSVDPTVDPLKSLASNISFGTEVEVQLGKRLQASVVRQMKDSEMAMQWTLIYQLTSRLRVLLQSAPSKRLLFEYSATSQD
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
Subcellular Localization:
Cytoplasm. Mitochondrion matrix.
Sequence:
MAATYCAYPAASAAAANPTRRHLQTLTAPGALPAARKPSRQAPTFLSFRRPNAALRPLRVAGADPQIVNGEDFPPMNDLIRLYKKAFLDGNDDVVSDIEKAITSMEEERSKAASQLESITAEIASGKNKFLRLNADLENFRKQAEKDRAKFTSNIQVELVQNLLPLVDSFEKTNVEVTLETEKEQKISTSYQGIYKQLVETLKSLGVGVVETVGKPFDPVVHEAIAREESTEFKAGIVSHEVHRGFLLRERVLRPAAVKVSTGPGDQIAGATSSEEPVEDTKEDAAV
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Regulates phagocytosis and macropinocytosis.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell projection, pseudopodium tip. Cell projection, filopodium tip. Note=Located at the tips of filopodia and at the tips of pseudopodia. In strains IR1, IR3, NC4A2, AX2, always enriched at the ends of actin protrusions. In strains AX3, AX4, JH8, JH10, DH1, does not seem to associate with actin structures in vegetative cells, but similar to other strains in developed cells.
Sequence:
MVLITRYLPSVTDNNQPALEGQSKDQIVDTVITSTTVGIINQLTMLVAHSNSIFTALANDANLVTQRIEKLGSRIRPLIQSIPSIEDYHRNTSIDTMNSKPRAEFHADNSERNQHFTHASIPASINTVYEKCKPPPNLQLLDPYMDDGQKSLKLYTNPDFFMDEWVAEQQKLHEEARQRKRERREARLKKKGEKNEVEVKKVKSVTKVRYDPVTGEKITINIESPHTSSPQIQHQSNNTATPQHTTQHFGTNQYQAPPPPPLSQSSPSQQHSPINSYTPPPPPLNTSTPSPSSSFQGRPPSTGFNTPPPPMSNNNNMPPPPPMQQNGGAANNRLSVHNSAPIVAAPAPPPPPPPPSAPAPPPPPMAKAGGGASDIKPKASGARSDLLSSIMQGMALKPAEERKVAEAPKKEEALNVADILARRIAWAGDSDSSEDESDDSDWD
The following text describes a protein:
Function:
Component of the RAVE complex, which is required for stable assembly of the vacuolar ATPase complex V-ATPase under many conditions. May be required for transport between the early endosome and the late endosome/prevacuolar compartment (PVC).
Miscellaneous:
MISCELLANEOUS: Present with 2860 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=May be membrane-associated and localize to early endosomes via its interaction with RAV1.
Sequence:
MSVDLFPNDRFGAEDKYDNFKDAVKECSWLIEEIVKPQLPNIIDNFSKCLEMLESDQIFKMPVSNGIPNESNKQNDSPTVKGVITRQGQYIVDFHIVVRFPQFQRGKQVMFRMNTGLNFLLIQFSKIMTHLKNILEILNQLQVATDVSEFVSKFGVAMELLNHSLILLQNPPRDLVFPEDNNFAMKEMFQDCYSVCESTAHILGLELTLCRNELCIELRNLIKVTKKPWCEIDSKTGRSFCDQIRNQVTNERNKTLSKILSENGVQVQDSTLLNHIISSFQSEAITLPEAQELLRRGVTFDNRVVMECEKLIVSTSDPTLISISAKLNSLKASMANHQANLVASKQLSTYK
The following text describes a protein:
Function:
Involved in pre-rRNA processing.
Subcellular Localization:
Nucleus.
Sequence:
MSRLIFLNLPSTLNPDTFRKTLLSPATLKSTTITDTKLVPKRRFAFVGYKDAEEAQKVKEWFDGTYAFGGGKVKVDFVKDEPLKTGDKLNRGEKSKEKRSKEGRDNVQEKQEPNKRLQEFMSVMKGVDPAMASPEASTSTAEGTKKEKSVKGKEKSEEPEEAEADDDDAAWLRRRQAALEGEPSTPQLSADEQLILSTSRLFVRNLAFITTSESLSSHFSTYGRIDECHLPVSQTTGEPLGTAFLQFHNAEDALAAYKALDKTIFQGRLLHVLPGRAKPGQEGAAAGSGVVDGKVLGKRDEGRGEVKSKVDAKRKQESAKGVNWASLYMNSDAVAASVADRMGISKSELLNADSGNSAVKLALAETTVIEETKKYFEEAGIVLESLQPRVPRSQTTILVKNIPYGTSIQSLTDLFAPHGKLTRVLLPPAGTLGVVEFENHMDAGRAFKALAYRRLGNAVLYLEKGPVGMFKSETAPGVGPISTEQKREEEAKALAEKVESLPEQPDPTDEAGSTLFLKGLNFTTTTPHLQTVLSHIPGFSFARVQMKPDPKRPGEKLSMGYGFVGFKTKEAATKALKALEGFEIDGKSLEVKFAQRGAEDDRETKKGGDAEGGKTKSTKVLVKNLPFEATKKDVRELFSAYGQLKSLRLPRKAVPTSTGAQSTRGFAFLEFTTHTEAARAMEALKHTHLLGRHLVLQWANEGEEVDIKGLREKVKGEVRGMEDGGDRKRRKLDFKGGKEDEMDGLEV
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Subcellular Localization:
Nucleus.
Sequence:
MEESGFCAAYERLPAKPATCIRFFDRGDYYTLHGDDALYAAKNIFKSQGVLKYYGAKKLPSCSMNQMLFETTIRDLLLQRRYRVEVFSSSGKSHQWAVTKKASPGNTQAFQDILYNSDLVQSSIVLAVTLQGSGNDQLVGVAFCDTAQASFGVCQFPDTAQFNNFEALLVQVGPKEVLLPSEQNNPLITKLSQISERYGAMVTPRRKADYQAKDVVQDLERLLKLAQDQKAAALPQVDEKAAMAALCCVIHYLDLLADDANTNKFRLSTFNFTQYMRLDSAAMRALNVFPAGPHSTKSHSLFGLLNHCKTLQGQRLLYQWLKQPLLDVNRIRERHDLETALKKMPDLSRLSKKFARQRARLQDVVSVYMAVKRLPDLIEHLQDFEGTHATLLHKQFLEDFTTLFEDFEKYLELVERTIDLEQADHQNYFIKPTFNEDMQKTREAIDTIEEEITSACEEAAEDLNLEYGKSLKCEQDAKSKQYLFRVTRAYDKLLRNNKAYTTIETQKNGIKFTNKRLSRLNEARQAQHDRYAEIQAEVAAKVIGIASGYEEPMEELNAVIAVLDVFLSLATASLRAPVPYVRPVMHAMGEGNITLKACRHPCLEVQDELAFIPNDVDLRREDGEFQIITGPNMGGKSTYIRQIGMAVLMAQIGCFVPANTAEIAVVDAVLARGISTFMAEMLETASILSAASRNSLIIVDELGRGTSTYDGFGLAWAISEHIAKTIGAFCLFATHFHELTALADELPSVVNLHVDALTSNNELTLLYKVKPGVCDQSFGIHVAEMVHFPAAVIEDAKRKAAELEDFENTGELGSTPDKKAKLEQREGEQLLSTFVDQVRSIQAEGLTPEQAFEKVAALRDKLAAHNNAYVRQRLGVRD
The following text describes a protein:
Function:
During the asexual blood stage and probably at the ring/trophozoite stages, plays a role in Maurer's cleft formation and/or morphology. Also, involved in the loading of the virulence factor EMP1 into the Maurer's cleft membrane. By binding to host chemokine CX3CL1, mediates the cytoadherence of host erythrocytes infected with parasite mature forms (late trophozoite and schizont) to endothelial cells, which sequesters them away from the circulation and thus prevents their elimination by the host spleen.
Subcellular Localization:
Host cell membrane; Multi-pass membrane protein. Note=At the ring and trophozoite stages, localizes to Maurer's clefts, specifically in the central region of the cleft. Localizes to the cell membrane of host erythrocyte infected with parasite mature forms (late trophozoite and schizont).
Domain:
The first cytoplasmic domain binds ATP and nucleic acids such as RNA and DNA in vitro; The P.falciparum Export Element (PEXEL) motif, also known as the vacuolar transport signal (VTS), is a pentameric sequence (RxLxE/Q/D) required for the translocation of proteins across the parasitophorous vacuole membrane (Probable). In the endoplasmic reticulum, the motif is cleaved after the leucine residue and the N-terminus is N-acetylated (By similarity).
Sequence:
MSFCYVRTISIALFLFIFLFLNNGNFKNNFYRKDNKYSSIKIRSFRSLAENQKVETEQSTPAKPEPTEFVNNDIHQNKNTFKKLKNNEKKKEILEEKMKDFVKLYVNKSSGECQRYRLQQHLKNYSSSNEYKKFMNKFVKFLKVHNDLNALKSQLHFNNVRAATIIFIAGFLSIFAILLTISAVAATSKFTNNMLAIAGVGALGSALSLPGMALLFVPAMLYVLNRKNEITNHYSERIIKQVSNF
The following text describes a protein:
Function:
Part of the ABC transporter DppBCDF involved in dipeptide transport. Responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSDTPLTFAPKTPLQEFWFYFKQNRGALIGLIFILIVALISILAPYIAPFDPTEQNRTALLLPPAWYEGGNPAYLLGTDDIGRDILSRIIYGTRISVFAGFIIVLLSCAFGTSLGLISGYYGGVLDTIIIRLIDIMLAIPNLLLTIVVVSILEPSLANATLAIAVVSIPSYVRLTRAAMMNEKNRDYVTSSKVAGAGILRLMFIVILPNCLAPLIVQMTMGISNAILELATLGFLGIGAKPPTPELGTMLSEARGFMQAANWLVTIPGLVILSLVLAFNLMGDGLRDALDPKLKQ
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannose transport.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Domain:
The EIIB domain is phosphorylated by phospho-EIIA on a cysteinyl or histidyl residue, depending on the transported sugar. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the EIIC domain. The EIIB domain is also able to transfer its phosphoryl group to a specific histidine residue in ManR, which leads to its inactivation; The EIIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; The EIIA domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the EIIB domain.
Sequence:
MKLLAITSCPNGIAHTYMAAENLQKAADRLGVSIKVETQGGIGVENKLTEEEIREADAIIIAADRSVNKDRFIGKKLLSVGVQDGIRKPEELIQKALNGDIPVYRSATKSESGNHQEKKQNPIYRHLMNGVSFMVPFIVVGGLLIAVALTLGGEKTPKGLVIPDDSFWKTIEQIGSASFSFMIPILAGYIAYSIADKPGLVPGMIGGYIAATGSFYDSASGAGFLGGIIAGFLAGYAALWIKKLKVPKAIQPIMPIIIIPVFASLIVGLAFVFLIGAPVAQIFASLTVWLAGMKGSSSILLALILGAMISFDMGGPVNKVAFLFGSAMIGEGNYEIMGPIAVAICIPPIGLGIATFLGKRKFEASQREMGKAAFTMGLFGITEGAIPFAAQDPLRVIPSIMAGSMTGSVIAMIGNVGDRVAHGGPIVAVLGAVDHVLMFFIAVIAGSLVTALFVNVLKKDITASPVLSETAPTSAPSEAAAANEIKQPIQSQKAEMSEFKKLTDIISPELIEPNLSGETSDDIIDELIQKLSRRGALLSESGFKQAILNREQQGTTAIGMNIAIPHGKSEAVREPSVAFGIKRSGVDWNSLDGSEAKLIFMIAVPKESGGNQHLKILQMLSRKLMDDNYRERLLSVQTTEEAYKLLEEIE
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MNSLIRRGLVSIRTSTVIKPSSFGLMRNNRFYSTENNQEAAKPEETENKPAPGSLEETIEKLKEELEETKKQLLYTAADRENVRRFAKEDNEKAKKFGIQSFTKELLEVVDQLEMATNLFPKEKLDENKELKDLHEGVKMTEQLFLKIMGNQGLQRFNPIGEKFDFNNHHAIFELNDPTKENNTVGHVVKQGYKLHDRLVRPAMVGVNKIKPQ
The following text describes a protein:
Function:
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MHSNILPVLTSVATLLGLVQGQSQQPYRDWAKAYEAAETLVLPWTLEQQANISVRDGTAPGFVPFEPSDGVRSVQGSGKDYDNPAMRTSSNLDDRTLHELYLWPWIDGVANGLGSVMCVMNRVNGIIGCENDHIMNGILKNETGFRGFIVPDVTAPVDKAAGLLGGLGWNSGYSVSEIMAAVKNGSIPESVMTEHALRIVATQLNLLQPPEEYAFPVETADLNVRDPSSKDFIRRAGSESIVLLKNKNNTLPLRSPMSLGIFGKDAANLATGPTPQSDFSNFAGDTYDGHLITGGGSYSPAPYVVSPLDALTARAADGQGFGYKYILSDNWTVTPSESTGEGFFQTSGVSVSQYARESEHCLVFINAFGKEGSDRRTLADETGDKLVNDVADYCGSTIVIINNAGVRLVDAWIEHENVTVFTDLIPCSNQVHTNMFCFPGCPERRRSRQESGHAIVDVLFGDVNPSAKLVYTIAKSKDDYNGQICECCECDYTEGLYIDYRHFDQAGIEPRFEFGFGLCFKSDGRANIAAYTTFTHSDLTINPSTDITTLQPYATGPITEGGPSDLFEQILTISASISNTGGVAGAEVAQLYLSFPDAAKAPVRQLRGFEKVYLEPGETKFVSFPIQRRDLSIWDEQTSKWKIVGGKYGVVLGRSSRDFTVEETLELLTI
The following text describes a protein:
Function:
May help in the organization of the PsaE and PsaF subunits.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MRDLKTYLSVAPVLSTLWFGSLAGLLIEINRLFPDALTFPFFSF
The following text describes a protein:
Function:
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type IV membrane protein.
Sequence:
MAAGSSNYWEDLRKQARQLENELDLKLVSFSKLCTSSRDGRRDSSDTTPLLNGSSQDRMFETMAVEIEQLLGKLTGINDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFLAIRERENLLGSVRKDIESYKSGSGVNNRRTELFLKEHEHLRNSDRLIEETISIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSFILGSIIGICTILLLLFAFH
The following text describes a protein:
Function:
Recognizes and binds in the vacant E-site of ribosomes stalled by some peptidyltransferase center (PTC)-targeting antibiotics. Makes contact with the PTC and both ribosomal subunits. Induces conformational changes in the P-site, which allows it to dislodge the antibiotic from its PTC binding site. Binds to ribosomes either directly following translation initation or subsequent to E tRNA release during elongation. Involved in resistance to a narrow spectrum of antibiotics (the streptogramin A antibiotic virginiamycin M, the lincosamide antibiotic lincomycin and the pleuromutilin antibiotic tiamulin).
Subcellular Localization:
Cytoplasm. Note=Does not stably associate with ribosomes.
Domain:
The antibiotic resistance domain (ARD) is packed between the 23S rRNA and the acceptor arm of the P-site tRNA and inserts into the peptidyltransferase center (PTC). The C-terminal extension (CTE) contacts the small ribosomal subunit, positioned in the Shine-Dalgarno-anti-Shine-Dalgarno cavity.
Sequence:
MKEIVTLTNVSYEVKDQTVFKHVNASVQQGDIIGIIGKNGAGKSTLLHLIHNDLAPAQGQILRKDIKLALVEQETAAYSFADQTPAEKKLLEKWHVPLRDFHQLSGGEKLKARLAKGLSEDADLLLLDEPTNHLDEKSLQFLIQQLKHYNGTVILVSHDRYFLDEAATKIWSLEDQTLIEFKGNYSGYMKFREKKRLTQQREYEKQQKMVERIEAQMNGLASWSEKAHAQSTKKEGFKEYHRVKAKRTDAQIKSKQKRLEKELEKAKAEPVTPEYTVRFSIDTTHKTGKRFLEVQNVTKAFGERTLFKNANFTIQHGEKVAIIGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQEVFDLPLEQTPEELFENETFKARGHVQNLMRHLGFTAAQWTEPIKHMSMGERVKIKLMAYILEEKDVLILDEPTNHLDLPSREQLEETLSQYSGTLLAVSHDRYFLEKTTNSKLVISNNGIEKQLNDVPSERNEREELRLKLETERQEVLGKLSFMTPNDKGYKELDQAFNELTKRIKELDHQDKKD
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEANAGDEGIHFQNYPFDFLEFLNHQRFEPMELYNHHEHAKAVAALPCAPPQYEYNHQTQPNHVQFASTSTSKPKEFKVEAPPSSSLSPSKKPDIATTQQFNNQPPITTTQTIFDSTFNAAQWGIVDLSSHQHLFNNLKRSLPVAQQLPAEDENKDDKNYFRRLKYLIDRRFPCTVCQKSFKQSSHLVQHMLVHTGERPYECNTCGRTYNHISSLIRHRRCHKEETEAEVTNSVPPPDGEAAAAAAVVAAAAAAMSEAAAGSAEMPVTGSEQSIPLPQDGPFTCTLCWKVFKKQSHLHQHQIIHTGEKPFSCSVCAKSFNRRESLKRHVKTHSDSMKVQCEVCGKSFRDTSYLLKHQATHTGERPDYKCELCGKSYAAPQSLLRHKQVHEQGLALQQPMVQQQQPLSEVIKEPTSSVTIEAASLLGTDVSNVGPAAISVIGKIGSFFSQSSLQKPPSVINNANKNFCCNVCGRGFGRRETLKRHERIHTGEKPHQCSVCGKRFRESFHLTKHHVVHTRERPYKCELCGKVFGYPQSLTRHKQIHRLQLPCTVATGTLPPDRLTFGCTDCGERFPDSFHLMNHKELHMNEKPYVCDTCGKCFGFIENLMWHKLVHQTAAERLHPISQCQDVAESQQVNCLETTAPSDVSGAEVAAAAAAAGVVASPFEEHPVVPSGERFSCSICGQSFKHFLGLVTHKYVHLVRRTLACNVCGQNFAGAYDLLLHRRTHLQKRHFTCSVCGKRFWEAALLMRHQRCHTEERPYRCTICGRGFLHSWYLRQHKVVHTGERAYKCALCNKRFAQSSSLAEHQRLHIVARPQRCPTCGKTFRYRSNLLEHQRVHLGEKVYRCDQCGKSFFYISSILRHQRSHDAKPDLRCSCCLKLFKDPKYFSKHVQTHQGGRPFKCGACGEAFSNTYGLKKHRHAHKMERLAAAATLVEGQKTL
The following text describes a protein:
Function:
Component of the glycosylphosphatidylinositol-anchor (GPI-anchor) transamidase (GPI-T) complex that catalyzes the formation of the linkage between a proprotein and a GPI-anchor and participates in GPI anchored protein biosynthesis. Binds the lipid portion of GPI-anchor. May act as an organizer in the transmembrane layer to recruit other subunits, and thus is essential for assembly of the complex (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAAPLALVLVVAVTVRAALFRSSLAEFISERVEVVSPLSSWKRVVEGLALLDLGVSPYSGAVFHETPLIIYLFHFLIDYAELVFMITDALTAIALYFAIQDFNKVVFKKQKLLLELDQYAPDVAELIRTPMEMRYIPLKVALFYLLNPYTILSCVAKSTCAINNTLIAFFILTTIKGSVFLSAIFLALATYQSLYPITLFAPGLLYLLQRQYIPVKVKSKAFWIFSWEYAMMYTGSLVVIVCLSFFLLSSWDFIPAVYGFILSVPDLTPNIGLFWYFFAEMFEHFSLFFVCVFQINVFFYTVPLAIKLKEHPIFFMFIQIAIISIFKSYPTVGDVALYMAFFPVWSHLYRFLRNIFVLTCIIIVCSLLFPVLWHLWIYAGSANSNFFYAITLTFNVGQILLISDYFYAFLRREYYLTHGLYLTAKDGTEAMLVLK
The following text describes a protein:
Function:
Lyase that catalyzes the C1-decarboxylation of 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid into 2-methoxy-6-(all-trans-polyprenyl)phenol during ubiquinone biosynthesis.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MIANVASGLGYQHESHQDDAESSINQETDTRKVLYNQHIPTTNFQRAALAFGSAFAALNDPRRHVMVADLGEATGQFALERLRSKMNADPSGRQILRERPRIHSSVVNLDKLRNFPEDSFGKAYVQFLDTNEITPDSRMPVRFVDDEELAYVMTRYREIHDFVHTLLGLSISVPNEIIVKWFEMIQTGLPMCMLGSFFGPLKLSLGDNFILTRYYIPWVVNTARKAKSVMNVYFEKQFDRPIETLRQELNITIPPNVPFEGKYI
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MASRFWTQGGSDSEEEESDYDEEVDTTVGEASGQAVTSRYLQDNASDSDDSDGQKRVVRSAKDKRFEEMASTVDQMKNAMKINDWVSLQESFDKINKQLEKVMRVTESERVPNLYIKALVMLEDFLAQALANKDAKKKMSSSNAKALNSMKQKLKKNNKQYEDLINKCRENPESEEEKEEEESDEEYDSDGEIIDPDQLQKPEAKSDSEASQYEDEKPDAGEGPWDQKLSKKDRLLDRQFMKNPSEITWDAVNKKFKEVVAARGRKGTGRFEQVEQLTFLTKVAKTPAQKLEILFSVVSAQFDVNPGLNGHMPINVWKKCVQNMLIILDILVQYPNIMVDDSVEPDENETQKGAEHNGTIRVWGNLVAFLERIDVEFFKSLQCIDPHTRDYVERLRDEPTFLVLAQNVQEYLERVGNFKAASKVALRRVELIYYKPQEVYDAMRKLTELTEDGDNGGEASEKEFEESRIPTAFVVTPEVVTRKPTFPENSRTLMDILVSMIYKYGDERTKARAMLCDIYHHALLDEFSIARDLLLMSHLQDSVQHMDISTQILFNRAMSQLGLCAFRVGLISEAHGCLSELYSGGRVKELLAQGVSQSRYHEKTPEQERLERRRQMPYHMHINLELLEAVHLVSAMLLEVPNMAANVHDAKRKVISKTFRRLLEVSEKQTFTGPPENVRDHVMAATRILRKGDFQKAFDIIVSLDVWKFVRNRDTVLEMLKDKIKEEALRTYLFTFSSSYESLSLDQLTKFFDLSVSRTHSIVSRMMINEELHASWDQPTGCILFQDVEHSRLQALVFQLTEKLSVLAESNEKATEARVGGGGLDLPLRRRDGQDYAAAAAAGSGTASTGGRWQDLSPSQPRQGSGRAGYGGRPMTLGQAAGSGYSRGRGRGSYGGSGRTSQRGSALRGPQGDGPARMVSLKGVRA
The following text describes a protein:
Function:
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
Subcellular Localization:
Mitochondrion intermembrane space.
Sequence:
MPPKKTIQEPNVNVPNGDAAKGRDIFDQQCAACHAFEGDDKTASAPTLGGLLGRKAGSTQFPYSKGMKGAGFNWSEKHLFVFLKNPSKYVVGTKMAFAGLENEQERADLIAYLANN
The following text describes a protein:
Function:
Involved in the fermentation of L-phenylalanine via a Stickland reaction. Catalyzes the reduction of (E)-cinnamate to yield 3-phenylpropionate.
Sequence:
MKDQYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNKRGIEFYVERAKGGTGLIMTGVTMVENNIEKCALPSMPCPTINPLNFITTGNEMTERVHAYGAKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGESAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGQDFPVSLRYSIKSFIKDWCKGGLPDEEFEEKGRDIPEGIEAAKILVAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKKVVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEQIKKVLIVGGGVAGMEAARVAAIRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLGVEIKLNVAASKENIKEFGADEVLLATGSSPRTLTIEGADKVYSAEDVLMERKNVGEKVIIIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLIDLIKFNKIDVKASSYISKKTDEGFVLNTNGEESIINADSAVVAIGYLSEKDLYSEVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
The following text describes a protein:
Function:
E2-like enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy and nucleophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for proper localization of ATG8 to the preautophagosomal structure (PAS). Likely serves as an ATG5-recognition molecule.
Subcellular Localization:
Preautophagosomal structure membrane; Peripheral membrane protein.
Sequence:
MIPYQEWHSQLQSLYDSQIFHNWALCQDVHLNDEKDGLLLRLIPTRQLQKNTERIENKLLNHIELYLTYSKVYNEPLLLLRIWEEKSIDGIPMTKLMLPTDIESLLDVQGKFQLGLDTIINLEGSVWYSFHPCDTSCIVGDQAEFMSTYLRRWVSIFIFSWLGYEDS
The following text describes a protein:
Function:
May play a role in a redox process involved in nitrogen fixation.
Sequence:
MHNIVCIKQVPDSAQIRVHPVTNTIMRQGVPTIINPYDLFALEAALGLRDRFGGEITVLTMGPPSAEESLRKALTYGADRAVLLTDRCFAGSDTLATTYALATAIRKIGKEYGPANLIFTGKQTIDGDTAQVGPGIAKRLGVGQLTYVAKVRSVDVANETIEAERRSEGGVQVLHTRLPCLITMLEATNQIRRGAMADALRAARAKIVKWSAQDAGVEDISKCGLKGSPTVVKRVFAPPARAERAALVESAEQPAQALIDAIFLNQPKLETDLATLARDARSGLSGQC
The following text describes a protein:
Function:
Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA (By similarity).
Subcellular Localization:
Cytoplasm. Mitochondrion.
Sequence:
MAARGVGLLTRLPVCSQRRNRIPRSISRLLSCPGTIAASIGSEEQSSVVAETGIEDKTLQKKFSEVQKERREQAQRTVLIHCPNNINEKKFLKYLSQHGPVNNHFFYESFGLFAVVEFCQKDSIKSLQNGTHTPTQSTEAAIPFKSRFLNLRLKNPSSQVSGQPFVQTTNQSPPSSKKLFELLSYAESIEEQLNTLLKAFQLTEENIRLRHLTCSLIEDIAAAYFPSCVIRPFGSSVNTFGKLGCDLDMFLDLDETGKLDVHKNTGNFFMEFQVKNVPSERIATQKILSVIGECLDNFGPGCVGVQKILNARCPLVRFSHQGSGFQCDLTANNSIALKSSELLYIYGSLDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTVMVIFFLQRRSPPILPTLDSLKSIADAEDRCILEGNNCTFVQDVNKIQPSGNTETLELLIKEFFEYFGNFAFNKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVELARDSAWILEQEDKNQPFSSSRQPWGLAALLLPPGSGHTSLSRKKKKKPMSEKVKGLLASIKSNSPDSSTDTSGKRTISTQA