lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6. Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6. Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm.
Sequence:
MVKLAAKCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAGRRAVDSAEARAWALGQGLECFETSVKEMENFEAPFHCLAKQFHQLYREKVEVFRALA
The following text describes a protein:
Function:
Lectin-like receptor for natural killer (NK) cells. Heterodimer formation with KLRE1 mediates NK cell cytolytic activity.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MHKKKHIKHGTNKQEIINIGTKSPTFQEKQRPSKTDQRSTVWREEQKKQELKVHRIFHPQPRTGFDVGKGIDPWLTTWQMITVILATLCIILVTKVGFLIPSLFSKGEKQSRKFSLLDPLCDRNDDSSCDFCSSDWIAFGNNFYCVFRENSKTWVESQSACEELNSHLVIIDSKAEVENLLLFEMDGWILHRMDGTNSSRLWGNDIKIRNTLMNDSEKKNHSCHYLRGNIFMPDECSAKKTYICEFNI
The following text describes a protein:
Function:
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
Subcellular Localization:
Cytoplasm. Endosome.
Sequence:
MASNNFFLPASVTSSGRPVLVPNEVECNLLSNVDIEHDQDDAVSFPPLKSGHFILTTHRLLFLSSSCSSTAVAIPLSAITHIFSSKRSLKSVFHSPRFRFQVSATPDNRIFDSDPGRVTGLRSVVITVVVRGKGDWELFLSKMWECWRGRAWAWETTPSETGPASASASASLYASDGSVRMVGVGGLLRKEQEMWESTDRSLQEAFQDLNALMNKAKEMVMLAEKMRQKLLAGSSSQSNSANDEELGSKEEMQDWLLSVGIVSPVTKESAGALYHQQLSRQLADFVKIPLERAGGMINLIDVYCLFNRARGTALISPDDLSQACSLWEKFDVPVMLRKFDSGVMAIQSKSHSDEESMMERIRFLGVIFSV
The following text describes a protein:
Function:
A C-terminal pseudogene fragment of BcsQ, which has a premature stop codon at position 6 of the intact protein. The mutation prevents cellulose synthesis, and has polar effects on transcription of downstream gene bcsA and probably also bcsB, bcsZ and bcsC. When the reading frame is restored cellulose biosynthesis is also restored, see (AC P0DP92) for an intact protein. May play a role in subcellular localization of an active cellulose biosynthesis apparatus at the bacterial cell pole (By similarity).
Miscellaneous:
MISCELLANEOUS: Cellulose production is abolished in E.coli K12 /MG1655 and W3110 due to a premature stop codon in this gene. The sequence given here starts on a GTG codon 6 nucleotides downstream of the premature stop codon.
Sequence:
MRGGVGTTTITAALAWSLQMLGENVLVVDACPDNLLRLSFNVDFTHRQGWARAMLDGQDWRDAGLRYTSQLDLLPFGQLSIEEQENPQHWQTRLSDICSGLQQLKASGRYQWILIDLPRDASQITHQLLSLCDHSLAIVNVDANCHIRLHQQALPDGAHILINDFRIGSQVQDDIYQLWLQSQRRLLPMLIHRDEAMAECLAAKQPVGEYRSDALAAEEILTLANWCLLNYSGLKTPVGSAS
The following text describes a protein:
Function:
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MGKKKKKRKSSAFKIILNVFLSIFLVAGVAFGGIVFAMIKTAPPLNVQQVLTFDEPSILYDDKGQYMDKVITNEQRIVVDYKNVPQNLKNAFVSIEDERFYKHHGVDIKRFTGVILINVTNKIKRSSKLQGASTLTQQLIKNTVLSSEVSIKRKVQEMYLSIQLEKELSKDEILGAYMNSIFLGGNALGVEAASKQYFNKSVKDLSLIECAFIAGVPQSPSVYYPYSSASKKNPSIYLNRTKTVLYKMLDNGYITQNDYNKALKDLDSKKLVFAKPSAPSNKLAYEWFSIPAIEQVKKDLKTQYKYDDKQIHNLLVNGGLKVYTTMNKNLQDKTQNTINNAYYLNSYKSNGMIYPQASAVIMDYHNGEVKTIIGGRGDQPARSYNRAASYNYLRPAGSSIKPLTVYSAAIDSKKATAATGFEDSPIPNNIGRKYSSGAPYNPKNSPDIYYGYVNVREALMRSINVVAVKLVDKIGLNTSIQYAEKFGIPIDQHDRSSIASLSLGELHKGTNPLIMAQAYGVFGNNGTYTEAKLYTKVVDRTGKVLLEPKTNTKKVLSPEAAFITYDMLQGPVSESGTGPQANFGNMEVRGKTGTSSDMKNLWFCGLTPYYSAAVWIGNDNSSTVDGVYSSTAARLWGDIMKEFHVNLPYKQVQKPASVVTANVDRISGKLPTQLSYRDPRGSTVYNEFFINGTIPTEYDDIHVEAQINKLTGKLASKFTPSFLVESRVFLRRDYSPGVELLDQQWLLPYSIDEGGSLPPTEEKNNSNTRDKNKDKNKNKNKDKNPSQDKPNNNNNDNNSNNNNNNNDNNNNTKPPENDSNQNHEDNKNKQ
The following text describes a protein:
Function:
Catalyzes the reversible phosphorolysis of cellobionic acid (4-O-beta-D-glucopyranosyl-D-gluconate), a probable step in cellulose degradation. May be part of a metabolic pathway where cellobionic acid is converted into alpha-D-glucose 1-phosphate and D-gluconic acid to enter glycolysis and the pentose phosphate pathway, respectively. Produces 4-O-beta-D-glucopyranosyl-D-glucuronate from alpha-D-glucose 1-phosphate and D-glucuronate with low activity in the synthetic direction.
Sequence:
MSAASPAPDDLATLMAPSADGMRYALYSPTAMPTAGGFLWNRRMMVQLTCRGYATAQFMQPEPAKYAHAPLLEARNFMMPEQPYYAHHPGRFFYLKDEDTGALYSVPHEPVRAPAETFEFSAGKHDVRWRVRHDGIVVELCVSLPTDDAVELWECRVHNQSGRTRRLSLYPYFPIGYMSWMHQSGGYSPELGGIVCRSVTPYQKVDDYFRQRDFKDCTFLLHEQPPVAWDAQQMAFEGEGGLHAPSAVQAEQLGNHDAHYENPAAALQYRLSLAPDAATVYRFAFGPAKDDAEIAALRARYLSAEGFAAAAQDYAQYLQAGRGCVQIATPDAALDNLVNHWLPRQVFYHGDVNRLTTDPQTRNYLQDHMGMAYLQPATARAALLHALSQQEPSGAMPDGILLVEGAELKYINQVPHTDHCVWLPIFLDAYLAETGDVAVLDAVVRTHDGQALSVAARLDAAMQWLLDARDARGLSFIAQGDWNDPMNMVGWRGVGVSGWLTVATAYALRLWSGICAANGRSAQATQFGQAVEEVNAAANRELWDGHWYARGITDDGVRFGIADDEEGRIYLNPQSWALLAGTADAEQRTALLAAVREQLHTPYGPVMLAPAYTHMRDDVGRLTQKWPGAAENGAVYNHAVAFYLYSLYQIGDADRAWEILRAMLPGPDMADALQRGHLPVSLPNYYRGAWHQYPRTAGRSSQLFNTGTVAWVYRCVLEGLFGLVGDGDALAVRPQLPSHWPQAQVTRQFRGAQFEVALTREPGRTQLEVQVDGVVSPDQRVHGIVAGRTYQLQVRLPG
The following text describes a protein:
Function:
Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.
Sequence:
MKNSPLNGLNGLKAFLETKPKEYHKFDPSRFIQIYKDFKNAFFEIQAKVIHVVGTNGKGSTGRFLTLLLADQNFKVLHFTSPHVFEFRERFFLNGSVVGESVLENAHQQLQSHAFSSACSYFEYATLLAVMLAKDCDYLVLEAGLGGEFDSTNALKKTLSVFTPIDYDHKEFLGDSLESIAQTKLKAMGSLSIIAPQQELVLNAAQKIAKEKHAKLIVVQNEISKGVRDYIERYHLARFLAMNLEVALKAFETLLPCNKQEVLKNLKPLNLIGRCELLSPNILIDVGHNPHSAKALKEEIKRIFNAKIILIYNCYQDKDAFLVLEILKPVIKKVLILELHEERVIKLEKLKGILETLGLEYALFEDVEENENYLVYGSFLVANAFYKRYQEKRD
The following text describes a protein:
Function:
Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
Subcellular Localization:
Virion. Host nucleus.
Sequence:
MAAMEANIFCTFDHKLSIADVGKLTKLVAAVVPIPQRLHLIKHYQLGLHQFVDHTRGYVRLRGLLRNMTLTLMRRVEGNQILLHVPTHGLLYTVLNTGPVTWEKGDALCVLPPLFHGPLARENLLTLGQWELVLPWIVPMPLALEINQRLLIMGLFSLDRSYEEVKAAVQQLQTITFRDATFTIPDPVIDQHLLIDMKTACLSMSMVANLASELTMTYVRKLALEDSSMLLVKCQELLMRLDRERSVGEPRTPARPQHVSPDDEIARLSALFVMLRQLDDLIREQVVFTVCDVSPDNKSATCIFKG
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling. The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane. PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase. PEX2 ubiquitinates PEX5 during its passage through the retrotranslocation channel: catalyzes monoubiquitination of PEX5 at 'Cys-6', a modification that acts as a signal for PEX5 extraction into the cytosol.
Miscellaneous:
MISCELLANEOUS: Present with 339 molecules/cell in log phase SD medium.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Domain:
The three subunits of the retrotranslocation channel (PEX2, PEX10 and PEX12) coassemble in the membrane into a channel with an open 10 Angstrom pore (By similarity). The RING-type zinc-fingers that catalyze PEX5 receptor ubiquitination are positioned above the pore on the cytosolic side of the complex (By similarity).
Sequence:
MSRVAQLDSIALDKELYGQFWSEFNAAFNTSEHKEEWELALNTVVFMCATRFLPHYGSSCTYGSALSGVVFQCRKRTLYVVTVLAGYVWKKITHIIFNGPHCGNQMMWLKLYKWVNLLYHGCDVTNFLRFLAAEGPNARAFLSPLYRAFNVHSTRLIRDGSAIASEFYSNSVFAGLEYQNRQLLWNALLELFSNTLLTKRGLLTFVKKPPRSRSTTTYKTVCPRCGGFPTNPYQIACCRANYCYVCVVKALEWSMCDACGSSGRLTASPVY
The following text describes a protein:
Function:
Serine/threonine kinase that regulates several signal transduction pathways. Isoform 1 modulates the stress response to hypoxia and cytokines, such as interleukin-1 beta (IL1B) and this is dependent on its interaction with MAPK8IP1, which assembles mitogen-activated protein kinase (MAPK) complexes. Inhibition of signal transmission mediated by the assembly of MAPK8IP1-MAPK complexes reduces JNK phosphorylation and JUN-dependent transcription. Phosphorylates 'Thr-18' of p53/TP53, histone H3, and may also phosphorylate MAPK8IP1. Phosphorylates BANF1 and disrupts its ability to bind DNA and reduces its binding to LEM domain-containing proteins. Down-regulates the transactivation of transcription induced by ERBB2, HRAS, BRAF, and MEK1. Blocks the phosphorylation of ERK in response to ERBB2 and HRAS. Can also phosphorylate the following substrates that are commonly used to establish in vitro kinase activity: casein, MBP and histone H2B, but it is not sure that this is physiologically relevant; [Isoform 2]: Phosphorylates 'Thr-18' of p53/TP53, as well as histone H3. Reduces p53/TP53 ubiquitination by MDM2, promotes p53/TP53 acetylation by EP300 and thereby increases p53/TP53 stability and activity.
Subcellular Localization:
[Isoform 1]: Cytoplasm. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Mitochondrion membrane; Single-pass type IV membrane protein. Nucleus envelope; [Isoform 2]: Cytoplasm. Nucleus.
Sequence:
MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQEPLNEVNSFPQKISYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESSTGLWPTISQFTLSEETNADVYYYRIIIPVLLMLVFLALFFL
The following text describes a protein:
Function:
Involved in the regulation of the onset of mitosis. Involved in a pathway that coordinates cell proliferation and differentiation. Implicated in spindle pole body (SPD) duplication (By similarity). May be a downstream regulator of auxin signaling in the formation of secondary roots (Probable).
Sequence:
MDREDNLPVQPDKPPKSLVRPILNLETTSSSSSSSSSSPELLRHLQAAFKRHRPLSKMQTTSIGPRRSVAPQRQASRNTRLVTAEGQRSQDVVTLSQSLAANTLTQDTTNNLAITSVAGESASITQPTVSEHFNPSDRQMDFGKSAVTSLESNLDVQRKSQSLIGTSQDMEWDATNQAEASHLDACIGSKHQNLPSVDSEVSLKSEYKDSSSLAKIQGQLGEFPNFLNQPRTRCSAVGSSWATTTLIHSSSAPMLNATTHVSRSYVEADSNANPHAVQSQGNLPSCCPSSKVSNILHPNKDATASEMPASTNDPEVRVKETDTSKQQQITTGLEAPVGSSIYGSDGQANARLPEELHTSVSSQPQKSDKHEKVASSKGPSAPRKRNYDPDLFFKVNGKLYQRLGKIGSGGSSEVHKVISSDCTIYALKKIKLKGRDYATAYGFCQEIGYLKKLKGKTNIIQLIDYEVTDKTLLQEVLNGTMSNKDGRVKEDGFIYMVLEYGEIDLAHMLSQKWREIEGSDRTIDENWLRFYWQQILQAVNTIHEERIVHSDLKPANFLLVRGFLKLIDFGIAKAINSDTTNIQRDSQVGTLSYMSPEAFMCNESDENGNTIKCGRPSDIWSLGCILYQMVYGRTPFADYKTFWAKFKVITDPNHEITYNQLSNPWLIDLMKKCLAWDRNQRWRIPELLQHPFLAPPIPHEPQVKTIKLFSLIAESCGSDDDKANSMISQLEQLLSNPAPLPRNDVLDSRDQNQQLLSRVSELCIQLQDRLQGLEGEN
The following text describes a protein:
Function:
Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives.
Sequence:
MAFDDLRSFLHALDQQGQLLKISEEVNAEPDLAAAANATGRIGDGAPALWFDNIRGFTDARVAMNTIGSWQNHAISLGLPPNTPVKKQIDEFIRRWDNFPVAPERRANPGWAENTVDGDAINLFDILPLFRLNDGDGGFYLDKACVVSRDPLDPDNFGKQNVGIYRMEVKGKRKLGLQPVPMHDIALHLHKAEERGEDLPIAITLGNDPIITLMGATPLKYDQSEYEMAGALRESPYPIATAPLTGFDVPWGSEVILEGVIESRKREIEGPFGEFTGHYSGGRNMTVVRIDKVSYRSKPIFESLYLGMPWTEIDYLMGPATCVPLYQQLKAEFPEVQAVNAMYTHGLLAIISTKKRYGGFARAVGLRAMTTPHGLGYVKMVIMVDEDVDPFNLPQVMWALSSKVNPAGDLVQLPNMSVLELDPGSSPAGITDKLIIDATTPVAPDNRGHYSQPVVDLPETKAWAEKLTAMLANRK
The following text describes a protein:
Function:
Required for asexual sporulation and normal colony development. May be involved in brlA activation. Could play a regulatory role in controlling the flug-initiated signal transduction pathway that triggers the asexual reproduction.
Domain:
The fungal-differentiation regulator (Fungal-DR) domain is only found in fungal regulator of G-protein signaling (RGS) proteins that regulate differentiation pathways. It is required for function (By similarity).
Sequence:
MPTSISTAPLSQGSPPSSLIDYQPQSVPSSSSPPPSTAAAAAAAVVVAVPSSSSPVDLGLPSFTSTSSLITSDVPATTTTPSFTGSVIGSISRRNRRSFAALAREKTSSALANLSSIGSTTNSSLRQSASSGSLQKHSRKASQLSVGEISGFVPLSPPLSDGSGSSEQSSSAPFEPLSAVTEQPNPAAERRRQTIQLVPPISENIPVSPAKMHQTSSRLLRMTEDDRPFTKDFMDLFSTLMVSLKLDSHRVRFTKYDHTFTSEEAINNLGSLKFSQSNRMPDPKDPSRIVTTTTTTTFSMAKEMARSVCQRFVDARFIESVDGKYSHTFPLKGALYQLTPKGINILQRFCQRNGITARHVIDVLESPRNTMQLVNLERDTETDKLSHDRATIEVIFRRFAGQDGPNVKSSVSSSDSDSLSDYSNGLVGVKMARERKVGDKICANTFTGKAAVDWLMDCSTTIEPRETVLIAELFVKYGLITVLQEDRSMPQVENSLVAFQPSKNAIYAITERGQRVCGWLARDKPRDTTTYDSRGIPRDSNNARLNHILQDPALRLLFREFLRFSLCEENLSFYIDVSEFTTQYHKFDKVGHFKKPDAVRETLAAAYGLYNAFLAPGSPCELNIDHALRNSLASRMTKAVGDDDSMLKSLQEVVQLFEMAQTSVFKLMSSDSVPKFLRDPKYSAILQEHDVDDLIGGGRSYSPTPGNVPERSMSRSQRS
The following text describes a protein:
Function:
Peptidoglycan-recognition protein probably involved in innate immunity by binding to peptidoglycans (PGN) of bacteria and activating the immune response.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPKTVVVTHPGKPINNEKRFRFELLYFCVILLMVVGLAAGYFMWMMSFSTHSPNKGLHILDRSEWLGEPPSGKYPHLKLPVSNIIIHHTATEGCEQEDVCIYRMKTIQAFHMKSFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPARQIEAAKRLMDEGVRLHRLQPDYHIYAHRQLSPTESPGQKLFELMQNWPRFTQDPTSLRLLSNETVKIVTRPYWLAQPPIVPLTPLKLPIESVRFVATNTPSCFTQAECTFRVRLLQNWHIESNGYKDINYNFVAAGDENIYEARGWDHSCEPPKDADELVVAFIGPSSSNKKIALELIKQGIKLGHISKNYSLIDDLEKS
The following text describes a protein:
Function:
Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.
Subcellular Localization:
Nucleus.
Sequence:
MENIENLKLYINSLSQSISAYESALSPLQNKQLSDMILNINTTSSTTSTTSTSEEQQIQILNNFAYILISTLFSYLKSLGIDTDSHPIKMELSRIKSSMNRLKNIKNEINGDTNKQEEEEEEKEKLKKSKEYLSRTLGVRDVGSSVDVKSMGTSAISKQNFQGKHIKFDDHDNADEKKDDGNKNDLKKSKNKKPNSTGSKSNSKSKSKLNVKESKITKPKSNKKSSTKNKNK
The following text describes a protein:
Function:
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
Subcellular Localization:
Cytoplasm, P-body. Nucleus. Note=Shuttles between nucleus and cytoplasm.
Domain:
Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex; The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.
Sequence:
MDYVYMTGGDPSNPRAEDIITLTMYDNDPTGAVPEYPDAAEYGAFNIGSSEAEYIEHGMMLADGGDRFGVSTVCFDTQEELIWMGNQGGHVTSYYGSAMQKYTSFQVHANEVVRQIVTIDTGILALTPTSLRHQLRRGIPKFTFRSERMVDMVCMIEHAPARLLMGGHQSDLIELDLATGTELTSVVAGVNGCAILRRHSRYLCAGDAYGKITLLDPNTLAIEHELPTHSGSLSDFDVQGNYLISCGLSGRQGNLTIDRFLMVYDMRMLRLVSPIQVLVEPQLLRFLPSHYSRLAVVSPHGQLQLVDTVELSEPRVCMFQINTSGSQCLSFDISATSQAMAFGDQSGHINLITAAKINTPTLQFNPYSRDTEFADTIEPATPFVPLTDTNFPLSSVLLPHLTTGERWLSDWPPWMNTYEHWRTKPIDPVVIATMKMQGPIGYAPNPRTGLRNQIPYLLDGTNGALAAGSAASTTHGSSAAKGGTGVEQQGMKLVPRRYRKVEVKYSKLGTQDFDFEQYNQTSFVGLEANLPNAYCNAMLQVLYFIIPLRKAILAHCCAKEFCLSCELGFLFHMLNVGSSSSPCQASNFLRSFRTVPEAAALGLILSSNSANVNLISLIQNWNRFVLHQIHSELLEALKKNETMHFYEQQPSQQQHTPEQDSVQKFQILNLGNGGKPAGGATATATQPHSAAGGQDESEIGRLFGTQQQTTHRCNKCNTTRVKDNVLLVCSLLYPTATTNNVEGTFGTILKHSLGVEKTTPAWCETCNKFTPTNQKSRVTGLPAILSINCGLDNEKELEYLKRQMSRSAGAHSSPSSQLPAGGNGGTGTPAGSGVATDQATGSVTFNGSGTGTKMCRYGTNCSRVDCHFAHPRKSSPCVISAASSSSTSAAASHGMQKSWFPLSFQMSLDEQQNLDISSLRTASNGEPVMPNVASEPDTPSDVEGKEETTPNEDPPPAQKVTKTYNLSAVVCYINDGSQHNLVSLIHVPSYYQQPKPGDAASTAGSWYIFNDFSISPVPVQEAVWFTLDWKVPCVLFYTSSVLAEEQCRLGLGLHSEQLTQYVNPFSTDLYEDESTDDGSVHRLTADSPSDAIDKADLEAKHPDNGADAAILFKPLGRTERFQAGDLVAMDAEFVTLNPEESEIRSDGKMSTVKPSHMSVARITCIRGQGDYEGVPFMDDYISTQEQVVDYLTKFSGIKPGDLDANFSNKRLTTLKNSYQKLRFLVDSGVIFVGHGLRNDFRVINIIVPPEQVVDTVHLFHLPHHRMVSLRFLAWQFLGIKIQSETHDSIEDARTALHLYKHYLRLQEKDEFSRALSTLYDTGKKLQWKVPD
The following text describes a protein:
Function:
Involved in vesicular protein trafficking.
Miscellaneous:
MISCELLANEOUS: Present with 2710 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MRVFTLIAILFSSSLLTHAFSSNYAPVGISLPAFTKECLYYDLSSDKDVLVVSYQVLTGGNFEIDFDITAPDGSVIVTERQKKHSDFLLKSFGIGKYTFCLSNNYGTSPKKVEITLEKEKEIVSSHESKEDIIANNAIEEIDRNLNKITKTMDYLRAREWRNMYTVSSTESRLTWLSLLIMGVMVGISIVQALIIQFFFTSRQKNYV
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MALNMNAYVDEFMEALEPFMKVTSSSSTSNSSNPKPLTPNFIPNNDQVLPVSNQTGPIGLNQLTPTQILQIQTELHLRQNQSRRRAGSHLLTAKPTSMKKIDVATKPVKLYRGVRQRQWGKWVAEIRLPKNRTRLWLGTFETAQEAALAYDQAAHKIRGDNARLNFPDIVRQGHYKQILSPSINAKIESICNSSDLPLPQIEKQNKTEEVLSGFSKPEKEPEFGEIYGCGYSGSSPESDITLLDFSSDCVKEDESFLMGLHKYPSLEIDWDAIEKLF
The following text describes a protein:
Function:
Acts as a cargo receptor necessary for the transportation of the cation transporter HKT1;3 and possibly other secretory proteins from the endoplasmic reticulum (ER) in COPII-coated vesicles targeted to the Golgi apparatus.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Located primarily in the endoplasmic reticulum (ER); may cycle between the ER and the Golgi apparatus.
Sequence:
MVFVWLTAFFLVVALIVLVIYQLMCLADLEFDYINPFDSSSRINKVVIPEFVLQAALSVLFLLSGHWAMFLLSAPMVYYNYTLYQRRQHLVDVTEIFNHLGREKKRRLFKIVGLIILLFLSLFWMIWTVLLEEDE
The following text describes a protein:
Function:
May be involved in sexual development.
Subcellular Localization:
Nucleus.
Sequence:
MELRSELPSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPPPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSAAAAAAVHKEPTYGGGLYGPMVNGAPEKQ
The following text describes a protein:
Function:
Sugar transporter that specifically mediates the transport of UDP-N-acetylglucosamine (UDP-GlcNAc) and is required for cell wall chitin synthesis.
Subcellular Localization:
Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MIASALSFIFGGCCSNAYALEALVREFPSSGILITFSQFILITIEGLIYFLLNDVQSLKHPKVPRKRWFVVVVMFFAINVLNNVALGFDISVPVHIILRSSGPLTTMAVGRILAGKRYSSLQIGSVFILTIGVIIATLGNAKDLHLHVESMTRFGIGFTILVITQILGAIMGLVLENTYRIYGSDWRESLFYTHALSLPFFLFLLRPIRSQWNDLFAIHTKGFLNLPSGVWYLCFNTLAQYFCVRGVNALGAETSALTVSVVLNVRKFVSLCLSLILFENEMGPAVKFGALLVFGSSAVYASARSKPKTNGLKKND
The following text describes a protein:
Function:
Probable protease (By similarity). Acts as a sensor of N(6)-methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its degradation (By similarity). Binds only double strand DNA (dsDNA) in a sequence-independent manner (By similarity).
Domain:
The RAMA domain recognizes and binds N(6)-methyladenosine methylation on DNA (m6A) (By similarity). The RAMA domain mediates interaction with histones (By similarity); The two acidic regions inhibit DNA binding. The two acidic regions promotes histone interaction.
Sequence:
MGSEPPSSPQVVEEGADEEDEELSGAEDADLRSSSGRGSLLTRRGITLRVLLKDGLVEPGDGVLSIHYLGKKFVGDLLNDGKIRWVETGQIFNSPSAWATHCKRLVNPAKKSGCGWASVRYRGQKLVQYKTTWLHKYQPSADMSLISEGEDDEMGDDDEEEGKTTIPVEDKNKKSKPELHEIGLTQRRDRERIPVRYCTLGTRDAARDPHTLVELSAFSAINRFQPFNVAVSSNVLLLMDFHCHLTSSEVVGYLGGRWDTNTQLLTVLRAFPCRTRLADKDAAPAVEEEICQNLFMRGLSLVGWYHSHPRGPALPSLQDIDSQMDHQLRLQGSSNGFQPCLGIICGPYYHGNQGVASTITPFWVVPPPEQRPNDHGIPVAVEVTYVQDNFLTTDVLNEMMLLVEFYRSAPDLVQFSQMWSPNTSILDKIKASLSGHAPKDQAYAQILEHVYNQLRNTQ
The following text describes a protein:
Function:
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c or a quinol are transferred to the bimetallic center formed by a high-spin heme and copper B.
Miscellaneous:
MISCELLANEOUS: This cytochrome oxidase is probably a cbb3-type.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSQPSISKSMTIGESGLAVVFAATAFLCVIAAAKALDAPFAFHAALSAAASVAAVFCIVNRYFERPAALPPAEINGRPNYNMGPIKFSSFMAMFWGIAGFLVGLIIASQLAWPALNFDLPWISFGRLRPLHTSAVIFAFGGNVLIATSFYVVQKSCRVRLAGDLAPWFVVVGYNFFILVAGTGYLLGVTQSKEYAEPEWYADLWLTIVWVVYLLVFLATIIKRKEPHIFVANWFYLAFIVTIAVLHLGNNPALPVSAFGSKSYVAWGGIQDAMFQWWYGHNAVGFFLTAGFLAIMYYFIPKRAERPIYSYRLSIIHFWALIFLYIWAGPHHLHYTALPDWTQTLGMTFSIMLWMPSWGGMINGLMTLSGAWDKLRTDPVLRMLVVSVAFYGMSTFEGPMMSIKVVNSLSHYTDWTIGHVHSGALGWVGFVSFGALYCLVPWAWNRKGLYSLKLVNWHFWVATLGIVLYISAMWVSGILQGLMWRAYTSLGFLEYSFIETVEAMHPFYIIRAAGGGLFLIGALIMAYNLWMTVRVGEAEVQMPVALQPAE
The following text describes a protein:
Function:
May play an important role in mediating p53/TP53-dependent apoptosis.
Miscellaneous:
MISCELLANEOUS: [Isoform 3]: Dubious isoform. Could be a cloning artifact.
Subcellular Localization:
Mitochondrion.
Sequence:
MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHGGCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGATVLRDRPLGSAFELSYDQKKAPLRLQ
The following text describes a protein:
Function:
Binds heavy metals. Contains five zinc and one copper atoms per polypeptide chain and only a negligible amount of cadmium (By similarity).
Sequence:
MDPETCPCPTGGSCTCSDPCKCEGCTCASSKKSCCSCCPAECEKCAKDCVCKGGEGAEAEEKKCSCCQ