lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MWTNVFRIGGLQLVSWFQLLPCEYDATTLTDKSVNAEGQKDASTLLVLSSHLQLQNEGYLSTWTNSFVGPWDPSQGVHNPDEKIKLWLFLPGRHTAIVGAAQPAVSRLRVVGAGLWVAPGDSEEVAIALSQALRNRIERAIRGLSYVRFGDAFTRCQSIARTEKHFRRVMHTFEFIFAATKEAIYVHVIVSAKRTRMLSGYDMEVVLRHNSSSKFGGLPVVVAPHGMRGSLTGCCPSDLVKQIYFSKAKALSSMTVLGIPFSVTPSSGCKVRGQNCYAEVSLGIPSSKVETTLLQNSPQGTVAKFDHTETHCSPGVAKSEGKQADYVQAFERTFIYPMEAVLVPVMNTILARTSLRRFWLQDLVGTLLLETSPLSDLSSPPFSMDCFVPGSLNRSDIPESSWIESNVLCHHFYNSSSNSNSSSSSSSSVYSTSSESDCEVVMGSEDLEADADSLASRKAVLSSYDMFENEGSKTVQASKRAHSEITDSFGQGLGPVKSARKGNESTAQTLAAGDGGSITDVYSSIDAHAISTAGAVKDRIVNPWDWGDDDRGVGMDIQTLLAEYGDLGDLFVNDVLDFGEPPGTAESQALMFPVADPGDIAGTPGTGGLDVSDQMLLPVLDFSSLEGFNQPPTAVKDDATSRVHEPMNEIQSSGAVSISSGHSAGELDLLSKAEAMLIFAPEYMAVESPSSTMSSATSTGYHYCPNSGKVDSYQKNSAVYSYGATPPPSPLMGSSDQIADTPGKVNDGLTKRDLLLELRKYYMVVQNVDQSGKRLPLGNNGIVSSKGETAFSASGFGSSSMMTSLHARKTEYESGAFCFLFPLRTVLATDVECLILQAAMCRIRHVVLSGSDGVPLGLNRAIALSVFDQVLSDASVLSGKISGNLEPKKKESIPVRIAGDIEGGLLDGSRSAPVGVWRSVGVPQGSKSPSAPKFDSSSLPINAYEEDGASFYGQKQPLQELLDAMGLLVQQATAFVDLSLDADYGDGPFGWLAFEEQRRRGFSCGPSMVHAGCGGVLAACHSLDIAGVELFDPLSADVHSSSVISLLQSDLKIALKSAFGERNLDGPLPINDWCKGRFQSIEGGSMSSDGCTVESMINDAKESSSTVTLGIGEPITPPQSSAGIKDSEQQMMPPRSKSTVMALSVPSILVGYQDDWLKTSANAIQLFEKAPLEPYALPKPMTYYVVCPDIDPLTTAAADFFQQLGTVYETCKLGTHAPQIVGNQIGLSSEKWSSSGFVLLDVPQSTEKPGSTFSSMGSISDFVLALSEGWNASSYCKSLSKVLRTLRLSSNLSANQKEVLGGTCMVIYVVCPFLDPDAVLQTVVESSRALGSTIFAYDKEKRSLLHSQLAKALSWSSNVDETSISNVLTLSGFSIPKLVLQIVTAETILRITRPPLTELVVLKEIAFTVYNKARRVPRCINPTEAAPLSILLGGRLRSTLTHVGSPVPGLWKDTVTSRNTGTALQRDGPLSWDSSWQAMRPGESLCDFSASGDVLSQDELRYLFEPLFILADPGSLEQGVSLTASEPSRYDETSGVCNNLGGSADTMAGTPIIDVSESDGVVGSCSQKVVSLHCCYGWTEDWRWLVCIWTDSRGELLDSHIFPFGGISGRQDTKGLQCLFVQVLQQGCQMLSSFATDAAIVKPRDIVISRIGSFFELECQEWQKAIYAVGGNEVKKWPLQLRRSVPESASGNGNSLQQQEISLMQDRAMPSQPNPSLYGSHSKSSSFLKGGLTQTNTRKQMLPGQLVGDAPRGVFQWVQSISFVAVSVDHTLQLICPVEMGASPTGVGSQGVGGPPSYWEGFSSVKSLGSTAASYMVIPNPSMRFLPPMPLQLPVGLTAESPPLAHLLHSKGLAIPLTTGFVLSRAVPTIRKDFMRNVKDEWPSILSVSLVDYYGGGASSNINAQEVSSSGKGGGVKQCRIPSSENSGLDAHQILEGVAAELHALSWMTVSPSYLERRTALPFHCDILLRLRRLLHYAEGQLCEQEKFQ
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSDLHLEGIAPRMRVLPVVYFSILDYHLRREARWEETTVIDPRTNQEEPRRNCKPINDRVIGCLLGTRTGNSVEVTNCFPVGHEDKEDTVDIRLDYFESLRALHAQANPNEEIVGWYSTGPELQHERSIFIHRTLCEDSMNDVHLWIDTSLDTGKLGIYAFTTASEGVPRLVDEEQDIYMPDQTFVPIACDVLVHEPERVALGLLNKGLEGGSSVKLVSDLNHVAEATTNLQDKIQDALTYVDKVLNGSVEADERIGRYLRDTVAAVPKIDPDQFEAMFNDTIQDLLMVGYLSNLAQTQVAIQDKLNDALATEI
The following text describes a protein:
Function:
Has antibacterial activity.
Subcellular Localization:
Secreted.
Sequence:
MKIHIFLFVLFFFLVPIATRGVKCAVKDTYSCFIVRGKCRHECHDFEKPIGFCTKLNANCYM
The following text describes a protein:
Function:
Lacks alpha-neurotoxic activity, has apparently no antibacterial activity, nor anti-coagulant potency.
Subcellular Localization:
Secreted.
Sequence:
MRYAIVFFLVCVITLGEALKCVNLQANGIKMTQECAKEDTKCLTLRSLKKTLKFCASGRTCTTMKIMSLPGEQITCCEGNMCNA
The following text describes a protein:
Function:
Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MRSENPCGKESHFLESPAVDALTGTQSKIFVCHPETKRSGVQRKKRKPRTDSIKCMQNFSLTTAEKAMNSEHNDAENSRDSLNSCDDLLDVTRKNPFVRLEACSFINTFVKSSMNGATSTFNVSGFFHKAQDERNSISPGGTVEWSDMNCSPNRMQDERSLIKDSLVFNKEGHFSCNQSKNSKFSREKKRSTVRKSRKKMKITEMSAMQTVLPDVTNECSKRALPAEAAVASSDSSATLGLNNQEVSLSNVYDCASHLHTESNTSEAQKSRKNRRKNSTKLLAFEDGCKKTSDLSVVAERKDSNTVASQCHPVTSGSLRALTHAHNVSYHHNSMTDEKLNKVRKKLQQFTCQRAIPMTGKHVWPIESCARTSGWIPKSCGSVSEGKIILSPVFAESSDESSVKTIGNSAVTGSLRQLVLHTSLAEVNKEPEHKIMDLNAGCLTSVEISESSSVGINETCRMSSENAESPVNMVKSAVPFNPDDMKEDEATSNFTTSAKDKGAVTKRNPSVAGQNTASKGKRNRVNLDHKASVVNQMLSDLKQTTVLNTRNLTSFKIPLRRNKPESGTLEPVSSFESKTCSLPELLDSSGVSGRQKRDEETTSIKVKQQPPPVVSDALSTASVKKKADEVNNKDFWHDGSERLSDEMSTLPDPVFLYPCRLERQLKSSAPDFCGTECVWKSEVSHHSGDTVDHRVALEIRDDSTSKVNLPQHKSEKFPDVLEAYNKDVLVIDVIQDDPDLFGTSGEEELTVTDSENCPAEACCSSIFVKEEKQCLECAVTSESSHSVNVQQILEMINLPRRYCRFYFMTLRGCERSKCWFWHVPKRGHEKICMAILKTYISINESGLLKRAVQIFARYYREVTPGENFDFQVLNDLLICLLKKCLLQEVFQMLNVTAQINTLPALEVLLRVFECVASLNVRDAVPTLISSFCKLVDAGMFLEYEHFNYIIKLLHQLQVSSQEIDTVLNIKCRYIFKELFYNLSHCKEKNDWAKLGALYVNARTACEHSDDLQKLSLCITEILTKDSEKDRPGVPFCDFADAGKTKLKPFPFLFSPFFLKGLIGSERLASRCQIVNTAAEIFLETESLDGAIRVLRESEWITNAALWPCSESDIISRHNLLFSLMHKYLRQSCYRQAFEVLQNLPGFQNGCDTVDVSQYSHVFNKLLNACFESKNLGVLSSAVDFMLSKNIAVDFFLLRGLITGLGRSCLWSKARTYYKTALSLGCYPPLEGNLRHKILPIPFYVSEVEMLLAIELFLVSNASDIQSPGATTQSFQIVLKRCEDQAVKNSSDYQAGRERLILAARLSDPKLFLRHMTVNVNMEEVYSLELTSALKWLKENMKWAGKVWLFQ
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
Subcellular Localization:
Nucleus.
Sequence:
MTTPLPLYIPNIEKQETPYNFDHLLQLCCVLFNFTILSFKVWFETQMGPRPGSYPMASQVNHKVETFDSHFPWTHQDNRFPATKDGSKSKPYAAVPIRSVAPTGEQHMNVKVKAKRQKVKKNKMSAKELREIASKLFKVEQPENKPSASKRTKGESRCGEATVTKNPNSVIADFCGVPPPFCSCTGVARRCYKCGVYGWQSSCCTTTLSEYPLPMNPSKPGNRLGGRKMTNGAYTKLLLRLAAQGRDLSNPVDLKNHWAKHGSNKFITIK
The following text describes a protein:
Function:
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity). Involved in the control of the switch from cell motility to adhesion via regulation of cellular levels of c-di-GMP (Probable). Part of a signaling cascade that regulates curli biosynthesis. The cascade is composed of two c-di-GMP control modules, in which c-di-GMP controlled by the DgcE/PdeH pair (module I) regulates the activity of the DgcM/PdeR pair (module II), which in turn regulates activity of the transcription factor MlrA and expression of the master biofilm regulator csgD.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSKQSQHVLIALPHPLLHLVSLGLVSFIFTLFSLELSQFGTQLAPLWFPTSIMMVAFYRHAGRMWPGIALSCSLGNIAASILLFSTSSLNMTWTTINIVEAVVGAVLLRKLLPWYNPLQNLADWLRLALGSAIVPPLLGGVLVVLLTPGDDPLRAFLIWVLSESIGALALVPLGLLFKPHYLLRHRNPRLLFESLLTLAITLTLSWLSMLYLPWPFTFIIVLLMWSAVRLPRMEAFLIFLTTVMMVSLMMAADPSLLATPRTYLMSHMPWLPFLLILLPANIMTMVMYAFRAERKHISESETHFRNAMEYSAIGMALVGTEGQWLQTNKALCQFLGYSQEELRGLTFQQLTWPEDLNKDLQQVEKLISGEINTYSMEKRYYNRNGDVVWALLAVSLVRHTDGTPLYFIAQIEDINELKRTEQVNQQLMERITLANEAGGIGIWEWELKPNIFSWDKRMFELYEIPPHIKPNWQVWYECVLPEDRQHAEKVIRDSLQSRSPFKLEFRITVKDGIRHIRALANRVLNKEGEVERLLGINMDMTEVKQLNEALFQEKERLHITLDSIGEAVVCIDMAMKITFMNPVAEKMSGWTQEEALGVPLLTVLHITFGDNGPLMENIYSADTSRSAIEQDVVLHCRSGGSYDVHYSITPLSTLDGSNIGSVLVIQDVTESRKMLRQLSYSASHDALTHLANRASFEKQLRILLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSMLRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAVNDYHFIWEGRVHRVGASAGITLIDDNNHQAAEVMSQADIACYASKNGGRGRVTVYEPQQAAAHSERAAMSLDEQWRMIKENQLMMLAHGVASPRIPEARNLWLISLKLWSCEGEIIDEQTFRRSFSDPALSHALDRRVFHEFFQQAAKAVASKGISISLPLSVAGLSSATLVNDLLEQLENSPLPPRLLHLIIPAEAILDHAESVQKLRLAGCRIVLSQVGRDLQIFNSLKANMADYLLLDGELCANVQGNLMDEMLITIIQGHAQRLGMKTIAGPVVLPLVMDTLSGIGVDLIYGEVIADAQPLDLLVNSSYFAIN
The following text describes a protein:
Function:
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MATASTTTVYGGDEINAIVLDPGSYTTRIGYAGDDFPKVITSSYYGQVKNDKKKIFGESINVPRANYDIKPILKESIIVDWDAAIEQYQYYFDQQLKVVGPEQPILITEPIWTETSYRQQLVETFFENFEFSGIYLAKSPTCVSFQQGRSNCLVVDLGHDSVSVTPVIDGICLLKSSMKTNYGGKFLSNEIQDYLIDTKKVVMEPSFKIKSKIPTTYPDPPKYELKNNNTIPTSSSSSLSQSFLEFQNEKIYHNFKEILEVPEKNSSSGTTTTTTTTNKDSSRLFELPTGQSIVIDRFKIAESIFDPTIYKFTNSKLSFPPNNGEISITQANEYRPLKRVRKNDDEEEDSNQSTPKPEVNIRGISQLISHTLSNIDIDLRASLANNIIVTGGVSLISQLTERLYLELSNNNPGLKIRLHAVGNSTERINQAWIGGSVLASLGTFHQMWVTKEEYNEVGVDRILNQRFR
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGKLIRRTSLTSKIINLPIDYFIYVCEQFDSVEWDKVSDRYSIPFSLAVNFIFLLMRIYIKSTHVPVQRNQLFVDKQSINTSRSWFRAFLSFLSICFLFISFLNFIFSTRFQNKLYRTLPQDKRTTTSTPNVKPVFQHSNNDDGDEQVFELKVWSPNQFLLNFACLFSPAHALILWFYSTSLRVTLLTFLLSFTTLHFVNKFSLLLKDQQYLHRQVFFEYDKKFVEPRLSVVKRDVAINTTRGPTTASIEYFTPRKPIDTFLEHRSSSHDHLTSTPRTPIALQRRSVHHLHDSGISRDSSSPFKRFPHLSDGSSRF
The following text describes a protein:
Function:
Transcriptional regulator involved in the activation of the purU-mabO-folD-nepA-nepB and mao-ORF55-nbr operons implicated in the nicotine catabolic pathway. The sequence GTTT-14 bp-AAAC seems to be the core binding site of the regulator upstream of the -35 promoter region of the operon.
Sequence:
MEQQVLTVRDLVTAQSLGMKVLSGAGGLDRQVLWAHSCELSDPDRWLGPHELLMTVGLCVPHSAVEQRNFIVKLDEAGLSGVALGDHNSLPPLTRELYEEADRRSFPVLLTNQATPFAAIGRTVAAATATTQTMQVLKLSKLYQLSTYARTDPLRMMNDLQALLRAGLSVFDVQTGLTIVEGAPLEFMPTSVRERTYALPGDSDSRLMISEYPGEEVSSFLLIHVLQVIDVALSQLLRSLRRRSERSTQMLASIFEGRSPDGLGSILGPSGTSSGYQFVAVALEDSEKVARAASIKSLPVLAGPGSSSFFILMPEQSRNDVRNLLHGLDVRAGVSSTYLDLRDAKAAADEAAKIFSSGGTNGLWTDFTGVPVSLLTRSRKEASAIVQQVLGRLAGTDPKITVLRETLFAFLANDRRWNETAAALGIHRQTLSYRLTRIKEITGRDIASSADLSAFWLAFQAWPSFSDRSD
The following text describes a protein:
Function:
Contributes to the transfer of mature mRNA from the nucleus to the cytosol. Required for both R gene-mediated and basal disease resistance. RNA export seems to play a critical role in stress responses and regulation of plant growth and development.
Miscellaneous:
MISCELLANEOUS: Unlike in mammals and yeast, NUP96 and NUP98 are not translated as a polyprotein.
Subcellular Localization:
Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Nucleus, nuclear pore complex.
Sequence:
MTSLSIQPFPEISRMARDLDSRKKRRISLDGIAALCEHSKEIIDSLPMLNSPDYFLKPCINELVEREIESPDYCSRVPDFTIGRIGYGYIRFLGNTDVRRLDLDHIVKFHRHEVIVYDDESSKPVVGEGLNKAAEVTLVVNIPDLTWGKQQVNHIAYKLKQSTERQGATFISFDPDNGLWKFFVPHFSRFGLSDDEAEDIAMDDAPGLGDPVGLDGKKVADIDEEDQMETSELELSHSLPAHLGLDPEKMKEMRMLMFPNEDEDESEDFREQTSHLMTSLTKRNVRPSQKIAQRNSHQDPPPVVRKTPLALLEYNPGNDKSSPGSILMVQQNKNLAVRKSKTGGFELDISHVTPLTDNYSRNVVDAALFMGRSFRAGWGPNGVLFHTGKPICSSSSQMVLSSVINKEKIAIDKVVWDRKGKVQKELIDSAFEAPLSLHKELNHVEEEVRFGSFSLKLQNVVTDRVVLSDICRSYIGIIEKQLEVAGLSTSAKLFLMHQVMVWELIKVLFSERQSTERLMYAASDNEEDVMQDVKEDSAKIDTEALPLIRRAEFSCWLQESVSHRVQEDVSDLNGSSYLEHLFFLLTGRELDSAVELAISKGDVRLACLLSQAGGSTVNRNDILQQLHLWRRNGLDFNFIEKERIKLYELLAGNIHDALQDFTIDWKRFLGLLMWHHLPPDSSLPIIFRSYQLLLNQAKAPWPVPIYIDEGPADGFVSDNKHSDILYYLMLLHSKEEEEFGFLQTMFSAFSSTDDPLDYHMIWHHRGILEAVGAFTSDDLHTLDMGFVAQLLSQGLCHWAIYVVLHIPFREDHPYLHVTVIREILFQYCETWSSMESQRQFIKDLGIPSEWMHEALAVYYNYHGDFVKALDQFIECANWQRAHSIFMTSVAHSLFLSANHSEIWRIATSMDDRKSEIENWDLGAGIYMSFYLLKSSLQEDADTMVELEPLDSTNESCRNFVGRLNESLAVWGDRLPVEARVAYSKMAEEICDLLLSDLSKNPSRETQLTCFETAFDAPLPEDVRSTHLQDAVSLFSLYLSETGQISA
The following text describes a protein:
Function:
During endoplasmic reticulum (ER) stress or when cellular ceramide levels increase, induces contacts between the ER and medial-Golgi complex to facilitate non-vesicular transport of ceramides from the ER to the Golgi complex where they are converted to complex sphingolipids, preventing toxic ceramide accumulation.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Nucleus membrane; Single-pass type II membrane protein. Note=Enriched at the nucleus-vacuole junction (By similarity). During endoplasmic reticulum (ER) stress, localizes to ER-Golgi contacts (By similarity).
Domain:
The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.
Sequence:
MFFAFLITYLLGGVTFLPFILFIYLLTRPTHKSEELRIIEPNNDCLTKLDKDIRIQGWIRVTTKFLQGKSGSVKVQEIPQDQLPKSSSDNAVTDRKTISPSGINNQYVIRNPKDVYYATVQAGKLHLFDPVKTSELLHVINLHEYLVVFYPGTVTENELFSNRNAIFLKYPAVSHKKESSTKSLLNKDLYVYGRTPSNKEDWNYALLSYSKISPAIKPLEAPIDFDYASVHHNLTALSSPDTDWLNAFIGRIFLGIHKTEGFKSLVVEKLTKKLSRIKTPGIMTDVKVIDVDVGEAIPTVNGLKFESLSNGGELIVSADIWYEGDCSFKAETTANIKFGSHFPSKTVPLALVIRLTHVSGKVRLLIKPPPSNRVWYAFYEKPRLHLIVEPMVARKQLTNNYLINFITQKLVELVHETIVMPNMNDLAFFIDNEAPIKGGLWDIELFRAPTIQKPAEKDAKAERKKSGLSSSTSEESLNRHISKRSSNSNDTAPSSHIIADKNLEPTSNIQLKKNPDGNLVETSELSDSDENSVLSNKSSTLSKKVVENTSPLKYTHSASKSFIGEVQDSLQALKTKAHKPRSIGGDSSQTTLSETTKKYGSVAKKSFFQGVSDAKSFVKKIKSTYIDDSSSNSPSDIESNYSADDNEISKSKAQNAIDFNVTNTHSPSRSISSEKSYKAAERGQQDKHNDVLVDLNPNVEAEKSNPHSNSQKTSKNDMSRNQRNKYAKEIMTGQPTLHPQGQLPIQNVEQRATHKPLPRPPVQVETREPVRPVPPIPKL
The following text describes a protein:
Function:
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built; The GINS complex plays an essential role in the initiation of DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MNGMNYFPNYYSIEDIFVTQEKVECRVNTKLQRMGFLDSGAESDDLEPGRTVNLPLWYIKELKVNNAYFTVAVPDIYRNVHKAVCEAETTHIELGRLHPYFYEFGRYLTPYDRNHVIGRIIFETLRQRVRHLLDISKSDGQAAKAEHRLDNIEAKLHEAGVRTNSQYIEWLQMTGNKIRTSELVEEHQKKRRRADRSDDEGDALPNSKRATL
The following text describes a protein:
Function:
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
Sequence:
MIRVIDCTLREGCQARQCSFDSAQSVQLAREIAALGVDMIECGHPRISADERERVRAVVAAVSTPVLAHARARREDIDAVLETGAQWVGLFASINAISLETKFKGMNREEVLELFHDAIRYARERGLRVRATVEDAARTSVSDLVSMIATARDAGADRICFADSVGILLPDETFDVLSLLRHEFPDVVFEYHVHNDRGLALGNTLAAIQAGVQWHSASCNGIGERAGITDTFQLLTLLHTKFAADRFNLKNVLAVSELVEAHSRIKRSPMHPVVGENAFVHVARLHQLAMQENQDAYSAFDPELINGRVSLQRYTPMHRQSLFLTPFEKSASELKYHRHGPGKRFVMLDRRLLDGSPFYFIARQFHDVGDGGPGHVDSHVHNCDSVFLFLGSDEDYRGLEVEVLLGGQLRRLQSPASVFIPAGVEHSYRYLGGSGTYINFVHKGDYHESLLEITQ
The following text describes a protein:
Function:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Subcellular Localization:
Mitochondrion intermembrane space.
Sequence:
MFSRFARAFPKILASGASQRTFATVQKAFANPTSKKLIVGSSLLIGSAFATTSFVACENKSVPLVGLPGTNQERSFIAIKVSSTQRRLIGEIIARFEKKGFKLVGIKILVPTPEHAAKHYEDLNKKPFFNGLVKFFSSGAVVAMVFEGKDVVRTGRVLIGATDPSQSAPGTIRFDLCIETGRNIIHGSDSNESAAHEIALWFKEDEIANWVSTNPVYEKM
The following text describes a protein:
Function:
Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space (Probable). Involved in the mitochondrial oxidative folding of the copper-zinc superoxide dismutase CSD1, the copper chaperone for superoxide dismutase CCS, and subunits of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in the peroxisomal oxidative folding of the copper-zinc superoxide dismutase CSD3, and the fatty acid beta-oxidation multifunctional protein AIM1.
Subcellular Localization:
Mitochondrion intermembrane space. Peroxisome matrix.
Sequence:
MGQAQSDENSIPTTTTTNTPPPSANSPRDSEDTSSPSMDSLLAEAAAYGEDDNENESLEAKAQRALDCPCIADLRNGSCGSQFSEAFLCFLKSTAEEKGSDCVNPFVALQSCINANPDAFSKSVTGDEKETEKKEEQPPVQDHRIIPPLWAKDPPRSGNSKL
The following text describes a protein:
Function:
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
Sequence:
MIKIGASILSADFGHLREEIKKAEEAGVDFFHVDMMDGHFVPNISMGIGIAKHVKKLTELPVEVHLMVENVDLFVNEFEEMDYITFHIEAVKFPFRIINRIKSIGAKPIVALNPATPLDAIEYILGDVYAVLVMTVEPGFSGQKFIPVMTKKIRKLKSMIVENGYDTKIFVDGGINVETAPLAVKAGADVLVAASAIFGKDDVKTAVKNLREAALEALNKDFLTKSFNSNEEKQ
The following text describes a protein:
Function:
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA. Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex. In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
Subcellular Localization:
Virion. Host nucleus. Host mitochondrion.
Sequence:
MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRITEMIPERNEQGQTLWSKMNDAGSDRVMVSPLAVTWWNRNGPVTSTVHYPKIYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTTTKEKKEELQGCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEARNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVNILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKALFQNWGIESIDNVMGMIGILPDMTPSTEMSMRGVRISKMGVDEYSSAEKIVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAVRGQYSGFVRTLFQQMRDVLGTFDTAQIIKLLPFAAAPPKQSGMQFSSLTINVRGSGMRILVRGNSPIFNYNKTTKRLTVLGKDAGPLTEDPDEGTAGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRNSSILTDSQTATKRIRMAIN
The following text describes a protein:
Function:
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity). Probably part of the elongasome which synthesizes peripheral peptidoglycan (Probable).
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MTSMRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFDQLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKKKKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHSSSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTLSPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN
The following text describes a protein:
Function:
Plays an important role in regulating the size of autophagosomes during the formation process.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MRAIVLLSVLISCYLVIAEDYYELLGVERDADDRTIRKAFKKLAIKKHPDRNTDDPNAHDEFVKINKAYEVLKDENLRKKYDQFGEKGLEDGFQGGNNYQSWQFYNDNFGIYDDDQEIVTLNRADFQRMVSDSNEIWFINFYSTYCSHCHQLAPTWRKFAREIEGTIRVGAVNCAEDPQLCQSQRVNAYPSLVFYPTGEFYQGHRDVELMVDFAIQRLKSEVLHLNSENWKALSEDWEPYNRLPWVVDMCGGDHIDCLSSTTRRKLSSMLDGLANVATIDCNAEEALCSKFNPITSGVMWFPARKLVKKSQINIESMDAQEISKSVIQYLDELEDISVESLQRLLEGNDPDEPIAVWMLANDAQSTERKDFRRLPALVTTQIFKFDCSKSSEICDELLDKTKLPQFMVFKTTGGYEIDYAGSKDFHAASTFIREASKSHIHVLNRDSYEYAISGGEFYIIDYFAPWCPPCMKLLGEYRRFHTATSEDSMLHTVAIGSLDCVKYKDLCQQAGVQSYPTSIVYTPDGKTHKMVGYHNVDYILEFLDNSLNPSVMEMSPEQFEELVMNRKDEETWLVDFFAPWCGPCQQLAPELQKAARQIAAFDENAHVASIDCQKYAQFCTNTQINSYPTVRMYPAKKTKQPRRSPFYDYPNHMWRNSDSIQRWVYNFLPTEVVSLGNDFHTTVLDSSEPWIVDFFAPWCGHCIQFAPIYDQIAKELAGKVNFAKIDCDQWPGVCQGAQVRAYPTIRLYTGKTGWSRQGDQGIGIGTQHKEQFIQIVRQQLKLDEHDEL
The following text describes a protein:
Function:
Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MLASRVVRGSWGALRGVTWEPGARPGKGRARGALLPPVPSCLAGRWWLRPAALGLRLPGVGPRGHCSGAEKAAPRSAPGEDAAAEARGGPASAASLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWASQKSALGSALDPLADKILISVLYVSLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPRTLSKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPVFNYADSIYLQILCPPVHSCVFFVVGSSSCGMWDAASAWSDEQCHVRAQDSNRRNTGPPAAERANLTTRPRGQPLVDTILKKLTIKYGMWKLYYRSFPAS
The following text describes a protein:
Function:
Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (rpb1); Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Ssu72 is required for 3'-end formation of snoRNAs (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MAHDPRLSSAGTATPNPPPPPPPPPPEPSTTGTGETQAAEPSAPAQSSDSFKLKFCTVCASNQNRSMEAHLRLSTAPSPFPVISFGTGSLVRLPGPSITQPNVYNFNTTSYSQMYDELLAKDERLYRNNGLLNMLDRNRNLKWGPERFQDWVPGMPRVDHVSKGDKGALGTEGGTVDVIITCEERCWDAVVDDLMNKGAALNRPVHVFNVDIRDNHEEALVGGKAILELATRLNDAATQERKIHGAEGWENGNGEARRSFDERVPEILASWQEKWPNLPALWTLAWL
The following text describes a protein:
Function:
Central factor in ethylene signaling pathways that control development, senescence and grain size. Acts as a positive component of the ethylene-signaling pathway.
Miscellaneous:
MISCELLANEOUS: Plants silencing EIN2 display a stunted phenotype with severe inhibition of shoot elongation and produce high levels of ethylene. 'Mao huzi' means cat whiskers in Chinese.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDGQQLRSSESPASGGGGVTGGGAPHLFHALGPALLISIGYIDLGKWVAAVEAGSRFGLDLVLLALLFNFMAILCQYLAACIGTVTGRSLAEICHQEYSRPTCIFLGVQAGLSLLTSELTMIFGIALGFNLLFEYDDLITGICFATVVPNLLPYAISHLGKKMVGTLNACIAGFALLCYVLGLLVSQPQIPLTTNVIFPKLSGESAYSLMALLGANVMAHNFYIHSSVVQGQKRSAFAVGALFHDHLFSVLFIFTGIFLVNHVLMNSAAADSTNTLLLTFQDVVELMNQIFVNPMAPTIFLVVLLFSSHIISLTSAIGSQVISQHLFGINLPLSGHHLILKAFAIVPALYCAKVAGAEGIYQLLIICQIIQAMLLPSSVVPLFRVASSRLIMGAHRVSLHLEILTFLAFLLMLFSNIIFMAEMLFGDSGWLNTLKGNTGSPVVFPSTVLITVACVSVAFSLYMAVTPLKSGSHEAELQQEWSVPSQKELLNTTQDREETCAGNVTYEEDQRSDVVPSPRIQPVDCLKSALDYIDSSDTAIESDHDSQHSTAHTSTAPESCHSPSFIPEESKSVVAVDWPEPLEPISNAIVAEESTVESVDSKSTGERDIEVEPALLMDNDKEAPNILESDNKPLGGNNPSCASDDGPPSLTFSRGKGSDAGNGSGSLSRLSGLGRAARRQLAAILDEFWGHLFDYHGKLTQEASSKRFDILLGLDVRTPSSTVRADSQANEIPKSPMVRDNLQGSAFLGSSRDLMSTKNEMSNLDLTYGLQMGNNIGSSAWSQGMQLPSTQLQSSSNSLLDQGARLNSNFSTPSYADNNQFYQPATIHGYQLASYLKQMNANRNPYSSMPLDPQRLPKSSASAVPTYVDSVMHARNQNLLASLGATPSQIAATSRIGTMMAERSYYVPSTLDGNENAGSSAYSKKYHSSPDISALIAASRSALLNESKLGGGTIGSQSYLSRLASERSQYTNSVARPAAPLAFDELSPPKLPGDIFSMQQSPNPSARSLWAKQPFEQLFGVSSAELTKSEFNPAGRSGGMTKDDFSYKESEAKLLQSLRFCISKLLKLEGSGWLFKQNGGSDEDLIDQVAAVEKLLQQGTSDNQLLLGDTQQPPCDKADIQYMRVLPNCGDDCIWRASLVVSFGVWCIRRVLDLSLVESRPELWGKYTYVLNRLQGILDPAFSKPRSALSACACLHRDIRVLNSLRHSSLVATNSIPRQIRGSFTTASVVLEMIKDVETAVSGRKGRSGTAAGDVAFPKGKENLASVLKRYKRRLSSKGQQ