lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MMKFLFGLLFMIPLTFLGGFWLNQLVWFVVSFLFIFSFSFSGLFSSISYEFGGDLLSFMMLFLSFWICSLMLLASEKIYLKNSWTGFFMFVVLMLMLSLYLTFSSLNLFIFYIFFEVSLIPTLILIVGWGYQPERLQAGVYLLFYTLLASLPMMISLFFCYGKFYSLHYFYLSGMVNSLFIYLLVNMVFFIKIPMFFVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGMMRLMIMFQEIGALINVIFIGLSLVGGFYVSLICLRQSDMKSLIAYSSVSHMGLVLAGVMTMNFWGLGGSLTMMVAHGLCSSGLFCLANISYERLHSRSLYMNKGLINVMPSLSMFWFLLLASNIAAPPSMNLLGEIVLINSLVGFSELSMIFLMLVSFFGAVYSLFLYSYSQHGCLYSGCYSYFSCSVREFLLLMLHWLPLNLLVLSGDLLVLWI
The following text describes a protein:
Function:
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
Subcellular Localization:
Chromosome. Cytoplasm, cytoskeleton, spindle. Nucleus.
Sequence:
MGKPFWPNVTGSTVKKARVYTTKKNRKKIQYNTRVVDDTWERMCKFNLGDVSPFSLDDSPVVKRLDARTDGQEESPVWSKDGGLCGEEAVKRGGPSPCKDVTSDWNNRTAPSSNKENNLKHKKKTRRVQNALDMSSDSDFLPSQKRKRKAPARQKKACSKKGTKKARTKAPVKTGQYSSNSEVQGKGANHSGLGHVISQKSMNFSNTWGEDETSPTYNNVLGDASLQNDKSSSSHAHNSSFFDELVRQRLDKFVTRDRKANTPPFFASPLDGTPSQAQRESGSTAQLESPSVDCMEPPVVMLSNISNTSNRELMENIDVVLAKVSSDSSEVLGSPKELSSAEFVVPESPIEEDASELCAELSPEATLFRTSTPCKQDHANNLRQESKRKPQGTRKQPSRRTKQSKGEADAPPPKRRRAKSRTTEDDGHDSNPRKVAKTKPSQGTRKQPARRTKQSKRDADAPPPMRHRAKSRITEDDGHDSESCHGNTTSKDRTLRTRQKKKSSKSVTPCSVIMSRLSEDDIQRLSAAGNRTSRRKKQSGNVRECQKDVKKGKNNKRTSAQQRQKSSTDDCFKTPKTPALRAVFTPNTRDLSTPGCRVTPTSSRRAKSPGSGVKQTPLRGSAGIPSRTQSNIMSPLFKKAVQNRLRMSPKEKLLLHCEQERILTFQECIPSETMKKCKKIGEGVFGEVFQTTKENGDKVAIKIIPIEGDFLVNDEPQKKFDEILPEIIISRELSELKHGTRNQTSGFTPLHRVCLVQGTWPKHLLSMWDQWHKERKEGSENDRPDMFPDSQLFIVMEFADGGCDLEHYQFHSLSQGKAVLHQICVALAVAEEALEFEHRDLHWGNVLVKKMDSGEKISTHRLNGEEVCIPTSGLEVNIIDFTLSRMQKDGQPLYCDLSADPTLFTGEGDYQFDIYRKMKEENQNDWKRHHPFTNVLWLDYLASKLLTKKFKSSKKCLKPWEQKFQTFRKEVLKCRTVAQVLKECQLFKDK
The following text describes a protein:
Function:
Structural component of the gap junctions.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
SGIRIHEVVERAADSNNVEEETRAKNIDLLSRHLQKALRFQRRIQRKKVIVHKTCKCLNLQYSSGFITSVYLFTKLLYAVNVVAQLLLMNQLVHELSRLVDQHIEFYTSFVAGVDGKYNRKTRYPLHSSFLRTNKYEWYGVDIIRDLISGVKWESSGFFPRVSVCDFEIRQMANIQKYSVQCVLVINMYAILFASSIFSIISWFFVMVFPCFSRWFVAQHLELSALHGFNPTNKRTSADVARFVHSYLHRDGIFVLRMLSSHAGVIFTTDLVCALYRAFYGIEECAESTDESQFDNRRNGKKAGFDFEGGGPIHDLPHAGHSTRRGIQIGDLLNVIQEGLTVPGRPRLAPVSQVGARGERGETSSSSQGEGVTERAQWLHEPREISYDTPREEVRSPRHHHHHHDQNTLSPKQAETPRSPQHHKSIDRLSSPTDPTRQDDLVRMLMDQ
The following text describes a protein:
Function:
Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSMVTKQDDAIEIRNVWNENLDHEMSLISQAINYFPYVAMDTEFPGTVCKKVTTEANPRRDDSTCYESLKTNVNMLNMIQLGLTLSDDQGNLPTLGTNKRRQCVWQFNFREFNLRTDMYAPDSIELLRRSGIDFDWNNRLGVESKRFADLLMGSGVVLNEEIQWVTFHCGYDFGYLLRLLTGRNLPDKQSEFLYLVNMFFPRVFDIKHMIGFCHDLFGGLSSLAERLEVERVGVSHQAGSDSLLTARVFRTMKETRFAGRSLDMYCGVLYGLGTITRTSVYFPVFKLIFKETPCRGKLLLRCGYAAFLNLRNHDEAAPVVVPPVAEPAAIIPEDMDLLTALELTLRKARAHGGVVRGLHESAKLIEKRVAQLCVLAEDCNQPDYVKLVKALCADHNINLLTVPSAKTLGEWAGLCKIDSEGNARKVVGCSCLVVKDYGEDTTALNIVKKHIESN
The following text describes a protein:
Function:
Located at the top of the head of the small subunit, it contacts several helices of the 18S rRNA.
Subcellular Localization:
Mitochondrion.
Sequence:
MLYILGARLLPDEQVRIALTKMDGIGPKKAIQLCYRLGISGNIKMNELTKYQIDQIEQMIAQDHVVHWELKRGERADIERLISISCYRGIRHQDGLPLRGQRTHTNARTARKLIRK
The following text describes a protein:
Function:
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
Subcellular Localization:
Secreted.
Sequence:
MHQRALLFSALAVAANAQQVGTQTPETHPPLTWQKCTAAGSCSQQSGSVVIDANWRWLHSTKDTTNCYTGNTWNTELCPDNESCAQNCALDGADYAGTYGVTTSGSELKLSFVTGANVGSRLYLMQDDETYQHFNLLNHEFTFDVDVSNLPCGLNGALYFVAMDADGGMSKYPSNKAGAKYGTGYCDSQCPRDLKFINGMANVEGWEPSSSDKNAGVGGHGSCCPEMDIWEANSISTAVTPHPCDDVSQTMCSGDACGGTYSESRYAGTCDPDGCDFNPFRMGNESFYGPGKIVDTKSKMTVVTQFITADGTDSGALSEIKRLYVQNGKVIANSVSNVAGVSGNSITSDFCTAQKKAFGDEDIFAKHGGLSGMGKALSEMVLIMSIWDDHHSSMMWLDSTYPTDADPSKPGVARGTCEHGAGDPENVESQHPDASVTFSNIKFGPIGSTYEG
The following text describes a protein:
Function:
Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MPYANQPTVRITELTDENVKFIVENTDLAIANSIRRVFIAEVPTIAIDWVQIDANSSVLHDEFIAHRVGLIPLTSDDIVDKLQYSRDCTCDEFCPECSVEFTLDVRCNEDQTRHVTSRDLVSNNLRVIPVTSRSRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSEIDEEEAEAPYDPTGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
The following text describes a protein:
Function:
Transcription factor involved in the regulation of multidrug resistance genes. Acts in concert with YRR1.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MKRRSDALLGSFQATNVTPPSDNSNSTAGGANGSNSGTPTSTSGKKRNKLIKSCGFCRRRKLRCDQQKPMCSTCISRNLTTCQYAEEFNKNIEKKATYGPYPNADLLKKVEELENKIRILEAEKNTNSSASSMYTSPNFPPLGTSVGRGSTETSSPLPDGVINPYADRYYLQSKHSGRSTLYGPTSMRTQIANSNWGFIEKYKQLWAKVKVERNKWKQNNQKTMCRELGLLDESDWQPDPLIKQICRFLPSYNKALSILDDFFNDGACNEINVILDKAKVRRDFLDYFMPEKEVKAEGDRSIVYILSNPKKNYYKAAVILLILCLKYFHTDVPTPIEKFFTLLKGASTAKVFYIERAQMLILFYYHRETYSFGGDGSDLVNINECLVTTVTTIGLHLNIRETFKEHEVFMGSIESLENVWLMAIFIDYNISCNVGRPLLINKFYLDENQDHCILNSKSKTYEGKLKRYLKLTRPMLLTLYDRDKFPDLKAYSKRIINFVEEELGPLGHYTGENISEEVPLRESRILSMAVGLLLSFYALIHSVLKVRNIESKNNTFQLVLINFSIIVNTTIRCYRIDKALYPEKFEASNPHLPPHMALSMSLTAGLFSKTLVFFCSLIYFKLTLFENGLCLSNDMEVGWSDLTKLTVPLDKDLSLGTAMSLYSSIFDRLFTVGNKELIRTMHRSSQFVIELAIERTYRTILGNVIEFRKLTEETWLAQIKQELDPQSDNPSSEAKIVSDRQRDLSLAVPTPTPSIIPMLPSPGETKNHAKSQSEIIQMLTDEFWANYNSGWEELINQSEFSTLFDDYKDN
The following text describes a protein:
Function:
Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.
Miscellaneous:
MISCELLANEOUS: In vitro, HdeA is more efficient than HdeB at pH 2 and HdeB is more efficient than HdeA at pH 3. In vivo, both are required for optimal protection against acid stress at either pH 3 or pH 2.
Subcellular Localization:
Periplasm.
Sequence:
MNISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFIDLNPKAMTPVAWWMLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQASNDLPN
The following text describes a protein:
Function:
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
Subcellular Localization:
Cytoplasm.
Domain:
The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.
Sequence:
MTRYARIIGTGSYLPPKRVTNHELAAQLAEQGIETSDEWIVTRSGIRARHYAEPDVTCSDLAAKAAERAIEAAGIDRAEIDLILVATSTPDFVFPSAACLVQQKLGLSNHCAAFDLQAVCSGFVYGLATADKFIRAGGYRNALVIGAEVFSRILDFNDRTTCVLFGDGAGAVVLQASDEPGILSTALHADGSHADILCVPGNVAGGAIKGSAFLYMDGQAVFKLAVNVLDKVAREALALAEVESSQIDWLIPHQANIRIMQGTAKKLGLPGERMVVTVDEHGNTSAASIPLALDAAVRDGRIQKGHHVLLEGVGGGFTWGAALLRF
The following text describes a protein:
Function:
Probable zinc protease.
Sequence:
MKVLVLSLSVQLVYIACIFLSGLVHAYSVRSVSSTNVTNAVLQDIAIYTFGQRISSTTPFNLSFTLDSEEWIVKLALEPNHDLIIQEPHINFHAGGEVQRTEVIRREHHKVFRGAAFVQSARYQWEKAGWARINIVRDGLSPLFTGAFTISGRQYDIKLESVRPGHFAAETETQIVAYRDTQDDINPIHASTTPSWSSPDVLQKRQFILDASDFVDSIGDDSGCPTNRQIALIGIATDCSFTASFDSSEELIQSLVSMVNTASEVFESSFNIALSFHNLTIMESGCPSTPSDDEPWNAGCSAGDLNWRLNEFSSWRSQLRGDDNAYWTLMTGCPTGTEVGVSWVGELCDSDMGANVVASAANQWQVFAHESAHTFGAYHDCDSSTCSLSGSSRQCCPLSESSCNAGGDYLMNPISAASQSEFSPCTIGNVCSSIGSRRVSMRCLTTNTNTPTISAGECGNGIVEAGEECDCGDECDGNECCDGSTCQFRGDAVCDSSSGDGGCCRDCQFLSAGTVCRAAVGECDIEETCSGNSGDCPDDETEDDGSSCGDDGEELFCASGRCTSRDLQCQEQISGDNSTISSCDNGADTCILSCSSPFATGSCSNAGTVLDGTPCDGGLCSGGVCQSSTRDYADVRSWVDRHRALVIGLSAGIGGFLVLVILVCLVCCCCRRRRPKSMSPVLMQPPLRPAAAARQMYMPPPAYSPRPVNGVEMASTPYFRYA
The following text describes a protein:
Function:
Thought to regulate endocytosis in coelomocytes through modulation of phospholipase C activity. Possible acetylcholine receptor.
Subcellular Localization:
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Sequence:
MLLLRLLPLAFLTIWHVQNATAISDGDRDFQNQILTGYNSKIRPVKAETTVTQVTVFLNIAHVEKVDEAEQTALVHGHLWASWTDEYLQWDRAKTNVTKITLPSHRIWQPALALYNSARGNTWHLYMAGMPATVYFNGKVWSSGTFSFFVTCQFDFENWPFDKQNCPIVIADWVYGLAQVNLSDPNMISEYAKPSIRLSYDPLERKNKRHVGGWEVMDAWKKHCYWGPKGCKEDQPEGEPDWYWSLLEFGIVLKRHLPYFQMTVMIPIFITSILVLLGFWIEKCALSSFIIFFNLALQTIYGYNIIKKLPPGSGTIPKVVQIFTLNLLLTGTQFFIAIMFGFIKEWAPKNFSFNFGIDITDIPKRMGIDTFFQSKGLSLFVDHDKIAAAEAGDDTSTIGIGNPLNDDEFDHFQNSATPSSNTDTELLINLPTNSDPENVLDSEKVENSEERKEKIPEASIENQLDLQLLHIKRFLFFLVVFIYCVAFLMILFL
The following text describes a protein:
Function:
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a role in axon guidance during nervous system development. May also play an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. More generally, may play a role in targeted cell migration and adhesion. Upon activation by ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively.
Subcellular Localization:
Cell projection, dendrite. Early endosome membrane. Membrane; Single-pass type I membrane protein.
Sequence:
MFKANQGDDNCLHCPINSRTTSEGATNCVCRTGYYRSDSDPMQMPCTTIPSAPQNVISSVNETSLMLEWAPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQFAPRQLGLTEPRVYISDLLAHTQYTFEVQAVNGVTDQSPYSPHFASVNITTNQAAPSSVSIMHLVSRTVDSITLSWSQPDQPNGVILDYELLYYEKELTEHNSSVVKSSTNTVLVPGLKAGTIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQSSFQEKLPLIIGSSAAGLVFLIALVVIIIVCNRRRGFERADSEYTDKLQHYTSGHSTYRLPSPGLGARSLVVTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNTLKAVAPLSSGVTLPLLDRTVPDYTSFSTVDEWLDAIKMGQYKESFASAGFSAFDVVSQMSMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQSVEV
The following text describes a protein:
Function:
Transcription factor involved in controlling responses to starvation. BZIP2-BZIP63-KIN10 complex binds to the ETFQO promoter to up-regulate its transcription.
Subcellular Localization:
Nucleus.
Sequence:
MEKVFSDEEISGNHHWSVNGMTSLNRSASEWAFNRFIQESSAAADDGESTTACGVSVSSPPNVPVDSEEYRAFLKSKLNLACAAVAMKRGTFIKPQDTSGRSDNGGANESEQASLASSKATPMMSSAITSGSELSGDEEEADGETNMNPTNVKRVKRMLSNRESARRSRRRKQAHLSELETQVSQLRVENSKLMKGLTDVTQTFNDASVENRVLKANIETLRAKVKMAEETVKRLTGFNPMFHNMPQIVSTVSLPSETSNSPDTTSSQVTTPEIISSGNKGKALIGCKMNRTASMRRVESLEHLQKRIRSVGDQ
The following text describes a protein:
Function:
May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen. Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MHLVPEGSESMSTQQNGSAQKPVTLNGSASTKGQAPEAPLETPGLIQLAICVLGIYASFLSWGVLQEAITTVNFPVRPPTAEEPNPPTERFTFSIVLNTIQSTFAAITGFLYLYFSTPAGKKVPSIFPTRKILFPLLLVSISSSLASPFGYASLAHIDYLTFILAKSCKLLPVMFLHLTIFRKTYPLYKYGVVLLVTLGVATFTLHHPGTSKKVAASAAKNQSGSSLYGIFLLSINLLLDGLTNTTQDHVFSSPQIYTRFTGPQMMVAQNILSTILTTTYLLVMPHLSSTGALHALLPIPIPPSTETELASAVSFLSRHPEVMKNVLGFAACGAIGQLFIFYTLSRFSSLLLVTVTVTRKMLTMLLSVFWFGHTLSAGQWLGIGLVFGGIGAEAVVQKREKQSKEQAKALTGKKE
The following text describes a protein:
Function:
Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.
Subcellular Localization:
Nucleus.
Sequence:
MARSKVKKVKPRKKKPLKLDKQFNCPFCSYKKSVDIKLHRSKGIGELACLKCGVKYVNQITSLDECIDVYSEWVDKCLEANKKGCNEFFFNDDLLSLNNLEDKDIIDQTIE
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MTVIVAGIVNKQGGIVLSRHFNDITRVRVEGLLSAFPRLMEASTNKQVTYVDAGAVRYVYQPLDDLFLVLITTRSSNIVEDLDTLHLMGRLITEHVGTVSEVFLQEKAFKVFFALDEVIVGGRRENTTTEQIQTYLEMQSHEEMMVREEKRLQMERAKKDASRKAHELRDKRQRGLNPYTGIGSDSVGYGSGGAAVSVSRPAAEASSRIDTMDELGPTRIAGMASGSADSLSGRKVGRGGGLALGVARKADITSRVLQEAGLPVGAVATKLPVGDAGAAAKAPEFDGPIEGIHVVVEEKISATLDRDGASGPVDVRGELSVLVNDPHLANVKLMLSPTSDEFSFRAHAKVHKEIFAEDRVLAMRENKPFPVHQPVTILRWRLNNSSGVQPPLTFSCWPNAGSITVEYEISNADLVEQGLCDVRVTLPLRGAVAATVESTTGSCSTQEDCVVWQIPQVSNHVNASGNCEVVLADPDCAASGADEVFFPVDVTFKTRATAAHVRVLEVVQTENGVPVKFTQETQLTAEGYNVQ
The following text describes a protein:
Function:
Transcriptional activator of promoters containing ATF/CREB sites. Can independently stimulate transcription through ATF/CREB sites. Important for a variety of biological functions including growth on non-optimal carbon sources.
Miscellaneous:
MISCELLANEOUS: Present with 1240 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MFTGQEYHSVDSNSNKQKDNNKRGIDDTSKILNNKIPHSVSDTSAAATTTSTMNNSALSRSLDPTDINYSTNMAGVVDQIHDYTTSNRNSLTPQYSIAAGNVNSHDRVVKPSANSNYQQAAYLRQQQQQDQRQQSPSMKTEEESQLYGDILMNSGVVQDMHQNLATHTNLSQLSSTRKSAPNDSTTAPTNASNIANTASVNKQMYFMNMNMNNNPHALNDPSILETLSPFFQPFGVDVAHLPMTNPPIFQSSLPGCDEPIRRRRISISNGQISQLGEDIETLENLHNTQPPPMPNFHNYNGLSQTRNVSNKPVFNQAVPVSSIPQYNAKKVINPTKDSALGDQSVIYSKSQQRNFVNAPSKNTPAESISDLEGMTTFAPTTGGENRGKSALRESHSNPSFTPKSQGSHLNLAANTQGNPIPGTTAWKRARLLERNRIAASKCRQRKKVAQLQLQKEFNEIKDENRILLKKLNYYEKLISKFKKFSKIHLREHEKLNKDSDNNVNGTNSSNKNESMTVDSLKIIEELLMIDSDVTEVDKDTGKIIAIKHEPYSQRFGSDTDDDDIDLKPVEGGKDPDNQSLPNSEKIK
The following text describes a protein:
Function:
Component of TORC2, which regulates multiple cellular processes to control cell growth in response to environmental signals. TORC2 is required for cell survival under various stress conditions. TORC2 positively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Positively regulates amino acid uptake through the control of expression of amino acid permeases.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKPVRRGQTDTALDISSHAKTNGDFIKKMNTTDSKRLKLLEDLKGKLEVECKIRDGAETLLQVFDTNFKKETKERKEMLKKKCTDELESSKKKIEELVSSIESFQGENGEAKTGSTSLTRSASATVSRKSSLQEKYSTRFSYKAGCSDSCSVTVSGTGELIGPTRNAHSNLTPTVIQRIDFENVNEKNNSSSEDTQPNGKRPSSLQSNFSQFPLNPWLDNIYKACLEGSMKDVIDSSNNLCEYLHEHSDPAYAKNFSLITPTILSMLELNVSEVTASVYRLLRHLFLDATAFSCCQMLNLPWILSKSLLSGTDAYQIEREQAFRLIRTLYFLSSTEGHEDYLSGITRTIISICEHVSDVSRGIAVETLIELMIIRPKILFKANGLRVLMISLIDGSISENLAASAALALVYLLDDPESACYVNLPYDIGILLSPFTSSSSRDTFNSSEEQSEQAAKAMKSSAKVASVLLNSWSGLLALSTNDFQALRSIVDTLRVPSFAPRSDVIDLFFLIFQVEYSSWSESFLAGKRLTVVKNQAVSNDDNINMVNIPDGSNKKYMSLRQHFTAVLLFIFLELGLVESIVCMIRASDDPSASRKATYLLGEVLRLSDELLPIHLGAKIQSLPSLFNMASQFTAEDRFVATSVLQSIESLNRVKFHSATQPFSQTTSLLFKEQKTDGSFRGQRQVEHVKLKMGMQIDDSHFRSMLAETNVLATKNYQKWRWDTLVQIMEGPLLSPKRIDETLRTTKFMRRLLAFYKPFSNRFSSIQNTKPNQKFIKVGCLVFRTLLANPEGVKYLSESKVIKQIAESLSQIDGYSEQVSEPIFSNSRLQKTLTHGYFPMLKVLSSQKEGHAIMERWRIFTTLYHLTELRNRDDLIIIFLTNLDYRLEGHTRIIFSKALNTGQQAVRLTATKHLAALINSESANDNLNHWAISLLIFQLYDPCLEVCKTAVKVLNEVCARNENLLAQVVQLQPSLAHLGEIGSPLLLRFLATTVGFHYLSEINFIEHELDNWYHHRNIDYVDLLEQNFFLSFVSNLKIIDKKNNEPDENILPLHFYGELVKSPQGCEVLESSGHFESFMGTLVEFYDKPLGNEAIRQLKSALWAIGNIGKTDQGITFLINHDTIPLIVKYAENSLIPTVRGTAYFVLGLISRTSKGVEILESLHWYSLMSLMGTSQGICIPRHAGQVLSTPRRNVEFVNERVPTPEFSSLLSSLTNSEREVIRLVSNLSNHVLTNESARQLTKIRSKNAKVFSSKRLVKACMTILGKFHYRVQIQQFVFELFPYSVLLSSSTSQDLNESPSRPNNLSISA
The following text describes a protein:
Function:
Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSYNHSECILRLDSSRYDSKMANKKRSQKAIQERTDKKRKLQDAQLENGLFGADVNSIDIGEEMPAKIASGKWEDNEQDYELKPRRMQDSEHELVEGLPIKINGKLERKMRVVQRAPENNEVSEDDSEKSEDESKQEESADEEDEEPDTEERILEMKELIAELVEKIIEEPEENTSALTRLRKMAESKNPNTSKFSMLALIPVWKSIIPGYRIRPLTEMEKKEKVSKDVARLRNFEEKLVHNYKLYIDHLASLARTANNEPALKVRLGNIAATAAVELAGSFSHFNFMSEVLTIVVRRVCKPNPSADPVFSKAIKVLETLMNEDDEGRVSAEIVRLLSRTLKVRNYNVDESVLNSLLSVDVLHDYDPNTKTDEPTKVKLKKKDRVHLSKKQRKVRKEMKEIEEEMRKAEQAVSAEEREKNQAELLKLILALYLNVLKANQQKLIGSVLEGLAKFGHMANLELLGDFLTVMKELISDADLNALSSAEVRKVLLCIVTAFSLVSNHRHMKLSVDLSSFVDALYSVLPYLSLDADVEFSHKTLRLADPLNNELVKPSVNVSTKAELLLKALDHVFFRSKSGTQQRAAAFTKRLYICMEHTPEKTTVALLKFLDKLMTKYPQIAGLYSTNDRIGNGTFYMEASTPARSNPDAATIWENALLTKHYCPLVVKGTKALFNRSKEST
The following text describes a protein:
Function:
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Forms a ribonucleoprotein complex with viral RNA. Binds microtubules and modulates microtubule stability. Can bind double-stranded DNA. Triggers host hypersensitive defense reaction in incompatible plants harboring resistance (R) proteins.
Subcellular Localization:
Host cytoplasm, host cytoskeleton. Host cell junction, host plasmodesma. Note=Binds to the host cytoskeleton before being transported to the host plasmodesmata. Observed in virus replication complexes (VRCs) of tobamovirus infected host cells (By similarity). In resistant plants, targeted to the host plasma membrane via the interaction with host resistance (R) protein TM-2 (e.g. tomato ToMV resistance protein TM-2(2), AC Q71BG9) (By similarity).
Sequence:
MALVVKGKVNINEFIDLTKMEKILPSMFTPVKSVMCSKVDKIMVHENESLSEVNLLKGVKLIDSGYVCLAGLVVTGEWNLPDNCRGGVSVCLVDKRMERADEATLGSYYTAAAKKRFQFKVVPNYAITTQDAMKNVWQVLVNIRNVKMSAGFCPLSLEFVSVCIVYRNNIKLGLREKITNVRDGGPMELTEEVVDEFMEDVPMSIRLAKFRSRTGKKSDVRKGKNSSSVRSVPNKNYRNVKDFGGMSFKKNNLIDDDSEATVAESDSF
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MALVGSFPFNYFLSRVLSCVGTAVLAVCLRIQVNKENKEFKDLAPERAFADFVLCNLVLHLVIMNFLG
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MMFGGPPPTKKDEGAILKRYTGPGFPFIPSLRHVVYPFHPHLHKGGPVKELTVPLRRKGGRGNDTGQIVTRHRGGGHKRRIRIVDFHRRASGEHRVIRIEYDPGRSAHIALIRKQGSTSTLSAEQAEESLAEGGHDNEAVKGGWSYIIAPLGLRAGDVVVSYRSGIPEKLIQQCDMTSSMYGSTLPSGETDAVSPPRKSRATDTPEMRRALGMLRTVTLKPGNVLPLYLIPPGMQVHNISLTVDGRMQLCRSAGTFGQVVSHQGSDGRSIGGSDVLTMGGGFDEEGNRVPKKGFVLVKLQSGEVRKLDPGCVATIGVVSNKEHQFRQLGKAGRNRWLGRRPHVRGAAMNSVDHAHGGGRGKSKGNKHPRSIYGTLQHVRTRRPKDKDGNKAVVTERPRGKQTAAKH
The following text describes a protein:
Function:
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKETFYITTPIYYPSGNLHIGHAYSTVAGDVIARYKRMQGYDVRYLTGTDEHGQKIQEKAQKAGKTEIEYLDEMIAGIKQLWAKLEISNDDFIRTTEERHKHVVEQVFERLLKQGDIYLGEYEGWYSVPDETYYTESQLVDPQYENGKIIGGKSPDSGHEVELVKEESYFFNISKYTDRLLEFYDQNPDFIQPPSRKNEMINNFIKPGLADLAVSRTSFNWGVHVPSNPKHVVYVWIDALVNYISALGYLSDDESLFNKYWPADIHLMAKEIVRFHSIIWPILLMALDLPLPKKVFAHGWILMKDGKMSKSKGNVVDPNILIDRYGLDATRYYLMRELPFGSDGVFTPEAFVERTNFDLANDLGNLVNRTISMVNKYFDGELPAYQGPLHELDEEMEAMALETVKSYTESMESLQFSVALSTVWKFISRTNKYIDETTPWVLAKDDSQKDMLGNVMAHLVENIRYAAVLLRPFLTHAPKEIFEQLNINNPQFMEFSSLEQYGVLNESIMVTGQPKPIFPRLDSEAEIAYIKESMQPPATKEEKEEIPSKPQIDIKDFDKVEIKAATIIDAEHVKKSDKLLKIQVDLDSEQRQIVSGIAKFYTPDDIIGKKVAVVTNLKPAKLMGQKSEGMILSAEKDGVLTLVSLPSAIPNGAVIK
The following text describes a protein:
Function:
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimerization of carbon 2' of dihydroneopterin to dihydromonapterin at appreciable velocity.
Sequence:
MMDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKSAKSDDVADCLSYADIADTVINHVEGGRFALVERVAEEVADLLLSRFNSPWVRIKLSKPGAVARAANVGVIIERGNNLK