lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity; The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.
Subcellular Localization:
Mitochondrion. Cytoplasm.
Sequence:
MYRLRSLIRPIRKYSMSRSLAIDEIASWDKELSKDLHHQLATTVLKNINADDALLNKTRLQEQDVRVFNTKLSVDCTPVTNQRASGRCWLFAATNHLRVNVVKELQLKDFELSQAYLFFYDKLEKANYFLDQITQSHEEPVDSRLVQYLLTDPTQDGGQYSMFLNIVKKYGLIPKDLYNDAAYSTTASRKWNSILTSKLREFAETIRETLKTKDVESKEFKELRTSMQKEIFRLMTLFMDLPPVKPDEKFTWTYQDKDKKVHTIESTPLEFASKYAKLDAAKPVSLINDPRNPYGKLIKIDRLGNVIGGEETLYLNVDNKTLTDLIVKRLKNDKPVFFGSHTPKYMDKKTGVMDIDLWNYHAIKYDLKQSKASRIEYHESLMTHAMLITAAHVDDDGNPVRFCVENSWGKDSGKDGMYVMTPEYFEEYCYQIVVDIDELPTDLAEKFDDKEPIVLPIWDPMGALAE
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALVTAFIGVDFFANGEQTYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMYASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTDPKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWATLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMTPEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFHLMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLVTAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKGVTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLAAWLWLGKRTLVTSIANSAPGRLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLNSMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR
The following text describes a protein:
Function:
Plays an important role in the biogenesis of the acrosome during sperm development.
Miscellaneous:
MISCELLANEOUS: Izumo is the name of a Japanese shrine to marriage.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane.
Sequence:
MGDLWVLLFSSLSLAAFHGVRGCLECDPKFTEDVRTLLGNLVPLEVPDRNQLLDRQHKEITHISSKVSHKDKMLRLLAVRNVIKLREWLKDEFYRLGNETWKGVFIIQGNLLEIRQNLEKKLTQIIKNFSEVACSEDCIVIEGPVLDCWNCLRMTTRCFKGDYCQDEDPKTAENREISLYLIFIAEAVILASAVLLFHVCISHRRKMKAIRRTLKTYLEKKLEELVEMIYKDDGEKNLEFGRSNSNSLTGEPTCAESEMQTGT
The following text describes a protein:
Function:
Receptor for angiotensin II, a vasoconstricting peptide. Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways (By similarity). Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Domain:
Helix VIII may act as a gatekeeper for either suppression or activation of the receptor, depending on post-translational modifications and interactions with various receptor partners. Helix VIII is found in a non-canonical position, stabilizing the active-like state, but at the same time preventing the recruitment of G-proteins or beta-arrestins. Upon switching to a membrane-bound conformation, helix VIII can support the recruitment of G proteins and beta-arrestins.
Sequence:
MKDNFSFAATSRNITSSRPFDNLNATGTNESAFNCSHKPSDKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLALADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKGSSLREMDTFVS
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MWLSWNTAQKDLYQDVMVENPNHLVSLGYQTSKPDALSKLAHGWEPLKTDAKVQNKNCPGIRKVDSHLQEHSPNHMQQCSGQNAFRNIVHLSKTHFSLVQNHNTFDLYRKTLKSILSLINQKRRHGINNLVEFIGGEKTLLHDKHEHTNTKTRFSENHQRTQKIEKLHLIYHENIHIEENPGSGQCEKLSRSVLFTKHLKTNTGDKICISNQYRTGSTVKSILIAHQQTYTEEKPYMYCECGKGFTMKRYLIAHQRTCSGEKPYVCNECGKGFTVKINLIGEKPYICSECRKGFTQKRYLVVHQQTHTGERPHICSECGKGFTVKSNLIVHQCSRTGAKSYICSECGKGFTVKCTRFTTKCTLIIHHRTHTGEKPYECNDCGKAFSQKIWLIQCERCHTGKNPFVCTECGKSYSHKYSLITHQRIHTGEKPYECNECGKAFTTKSVLNVHQRTHTGERPYGCSDCEKVFFHSSNLVKYKKMHTRERDRISQVENSCNGESQLLPYK
The following text describes a protein:
Function:
In association with cdk-4, regulates the progression through the G1 phase of the cell cycle during postembryonic development. Regulates proliferation of the coelomocyte lineage and intestinal cells during late embryogenesis. In complex with cdk-4, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP).
Sequence:
MDFESSSAGPSTSYAEEPCTLSMLPQVSAVLSETSITESNVSCQLHPSRSAALNDNVRTLIYNRTDPHIQLDMRAFYNCMEYEEALQPNYHYFTGVQENITPFHREQAIDWIYDVAKEENCDGDVFLLAVSLIDRFMSVQNILKHDIQMIAGVALFIASKLKAPHPMTASKIAYYSDNSCPIDMILQWELLIVTTLQWETESPTAFSFFDFLASRIPQIHNMRGDFQTVVQKCQKMHKLATLFPSMQCAIGLYYVSNLPTQNKELAVKIKDLLANMFQLEVNLLDSYIPMVQRCMSTTPIYTSEDAEKTEPTPSAPASTQEPEAFQELKELKEEPLPTPPPEEPAFQKLVLLEPIPLSEQTPSTPLNDSGFSSDVSSPASSEKKRRRSTDWFEEDSTPPKIFKTL
The following text describes a protein:
Function:
Involved in rRNA processing.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSQKRKHDDTPGDASSASKTFKKHRPFKPGQNHQQTKHHRRPNLSHDDENGRSTNALKSRIRDLKRFLTHMDSVEKHKMSAGARQERERELEACEHELAEKLNASREAEYRKKMIGKYHQVRFFDRQKGTRILKRLKKELSALEDDSKKTALQQRIHNAEVDVNYAIYYPLMKPYSSLYPKSKNKKSSDSEEAEDTGEDSKNSAEVDGPKGDVNMWKAIEEAMQDGTLEKLRYSKDAVPAEPPKKSKKPKAKDSKKEKSVSKTSHDASASHNYAVQDQDEDSDGGFFE
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Miscellaneous:
MISCELLANEOUS: Present with 1850 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Sequence:
MLQLKFIWPVARITPIYRPFTSHPFRNLATSSSISSTKAKTTKTDTTPLKLSNELYAIFKIHNRPYLVTEGDRVILPFKLKQAEVGDILNMTDVTTLGSRNYKLVGHPINTSLYTLKATVVGKTKRAFQTREVTKRRNRRVRHAKSKGDLTILRISELSMN
The following text describes a protein:
Function:
Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination. Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins. In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively.
Subcellular Localization:
Nucleus.
Sequence:
MASADGASPHVKSPTERNLKQVVLGDLLFKTWYQSIYPEDLVSKDTDRLYVCCWCFCYSCDVNSHVKHMRLCEHRTTPPGAQVYEHGGFSVWEVDGDEHKLYAQNLSLFAKLFLDHKSVFFDVATFLYYILTFTDPGNPEKYHILGFFSKEKLSWDANNLACILVFPPYQHKQLGKLLMGVSYKISAWEEDAGFIGGPEKPLSDMGARSYSRFWQERIGRRLLLDDTDASGQETQPARETRKRHSATFMTVRDIGEATGMLTEDVITALRGMGVVQPETPSKRRKAKQAADVPDHYATIRKSDLLRWMENRKVSLRDPVRDERFVGRWALRGTPDENDSIAGEGEEEEEEDSHTA
The following text describes a protein:
Function:
Methylates 3-aminomethylindole (AMI) and N-methyl-3-aminomethylindole (MAMI), two substrates involved in gramine biosynthesis, a toxic indole alkaloid. Can use S-adenosyl-L-methionine (AdoMet) as a methyl donor. Unable to mediate caffeic acid O-methylation.
Miscellaneous:
MISCELLANEOUS: Present and expressed only in cultivars containing gramine (e.g. cv. 5172-28:4, cv. 5172-39:9, cv. 5175-50:20, cv. Hordeum vulgare ssp. spontaneum accession 5, cv. Golf, cv. Lina, cv. Barke, cv. Sultan5, cv. Igri, cv. Salome and cv. Osiris) but not detected in cv. CI 16145, cv. CI 11506, cv. Mona, cv. Morex and cv. Maythorpe.
Sequence:
MDKISAPFFSGTSPAAASVAGVDEDDRLCFQAQELMFAYNISMVLRAAIQLGLLDALSAAGGKALTPNELVENVETSSNKAEAAAAVDRILRYLSCFNVVTCSSEAAGPDGTLVRRYTTGPLCRWLTKDRGDGTLSPFAVFVVDPDHLFPWHHIAEAVTAGGPSAFERTQKWPYYEYMGKNQRLGTLFDNAMAQHSVILVTKMLERFKGFDGVQRLVDVGGGTGSTLGMITSKYKHMTGINYDLPHVIAQGLPLPGVEHVAGDMYESIPTGDAVLLQWITLMLNDDEFVKILSNCHNALPKDGKVIVVDGILPENPDSSLTARDAFTLDIIMFVLFKGAKQRTEKEFARLAKQAGFTGGIKKTYIFFNFYALEFTK
The following text describes a protein:
Function:
Required for cytoplasm to vacuole transport (Cvt) vesicles formation and mitophagy. Involved in binding of phosphatidylethanolamine to ATG8 and in recruitment of ATG8 and ATG5 to the pre-autophagosomal structure. Protects ATG8 from ARG4-mediated cleavage. Essential for maturation of proaminopeptidase I.
Miscellaneous:
MISCELLANEOUS: Present with 6020 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Vacuole. Note=And perivacuolar punctate structures.
Domain:
Contains a beta-propeller domain involved in specific binding to phosphatidylinositol 3,5-bisphosphate (PIP2); The L/FRRG motif is essential for the cytoplasm to vacuole transport (Cvt) pathway and for the recruitment of ATG8 and ATG16 to the PAS in nutrient-rich medium and in both its recruitment to and dissociation from the PAS under starvation conditions.
Sequence:
MKVLQFNQDATCCVVAASSHQISIFNCDPFGKCFEIDTKNSKKKTSNNNGSASNSESRNNEESILITNGSRDRTDAEEEEDNEDNALVTGNILKEGEFVIEMLFSTSLIAIADRGQGLNKGKKLKIVNTKRKCTICEIVFPHEIVDVVMNRKRMCVLLESDQIFIYDISCMKPLETIDLWEDHYKRSQANSFSNASNTGTLEGDSANLNRVATNLLANATQKSVNGSNPSVRTRRNSLRSKIRPRMVLSNDDRSILCFTAYSSPKKNKPNSEALYDVVIYDTLNVTPVNYLNSVHKGNVACLAVSHDGKLLATASDKGTIIRVFHTGVDSDYMSSRSLFKEFRRGTRLCNLYQLAFDKSMTMIGCVGDTDTIHLFKLDDASNSLPGDNSSNGHWNEEEYILASNSNPSMGTPKEIPLSKPRIANYFSKKIKSSIPNQNLSRNFAYITVNESNRSCLGFPDEFPNQVYIASDDGTFSIYSIPSKPGECVLTKNNKFT
The following text describes a protein:
Function:
Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
Sequence:
MQDVTPARPTVLLTGAHSQLAKALIRTHLNGGLVFNLHPLTHAALDISDKYSVAEVFAQVKPDWVINCAAYNAVDKAETAVDEAYRVNSLGPELLATECALTGARLVHISSDYVFSGLLTGVEANALSETVTPSPLSVYGKSKLAGEQAVQRILGERAIVIRTAWLYGVDGHNFVKTMLRLMAATPDAQPLFVIDDQIGSPTWVDALASLIWQLMLRGESGLFHYAGQGQCSWYEFAAEIQQQALALKLLKKAVPIIATDSLSYAAKALEKGNVLAQRPSYSALNSAKLRDTLGKDNLAAIQCPEVWQDWRVQLNCMLNALITQSAKP
The following text describes a protein:
Function:
Mediates sugar transport across membranes.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MESLSQTLQPHKDTVGTVASYLTILQFFSGVFICRDIYKKGNTDGVNSMPFVGGIMLGLAMLKYGLMLGDENMLLVNLFAIVLNVIYCIVYYFYSNDKWKQILKPLSISMAFVAVLWGYCEYESPSVVEFRYGLIVTILMLAVLGSPLLGVKEIIEKKDASEIPFVLTLMATLVTFSWLLYAIILKNEFMLVQNVAGFVLCFVQLILIFAYPGGGRQVSKKKKKH
The following text describes a protein:
Function:
Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
Subcellular Localization:
Periplasm.
Sequence:
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMTIDSNSNDCNMLDDSGKCRFSGKVVITQGTLEIHADTADIFQKNGQTDRVVLNGKQATLKQEMDDGAMMNGQADNIEYKVADEIIILTGNYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQPKTAAPAAAPAPAKPQGKK
The following text describes a protein:
Function:
Transcription factor that binds to the DNA sequence 5'-ACTCAT-3' in target gene promoters. Promotes POX1/PRODH1 expression in response to hypoosmolarity stress. Positively regulates the expression of ASN1 and POX2/PRODH2 genes, which are involved in amino acid metabolism. Regulates several metabolic pathways such as myo-inositol, raffinose and trehalose. Regulates several trehalose metabolism genes, including TRE1, TPP5 and TPP6. Mediates recruitment of the histone acetylation machinery to activate auxin-induced transcription. Interacts with ADA2B adapter protein to promote ADA2B-mediated recruitment of SAGA-like histone acetyltransferase complexes to specific auxin-responsive genes.
Miscellaneous:
MISCELLANEOUS: A highly conserved upstream open reading frame (uORF) coding for 42 amino acids is essential for the BZIP11 sucrose-induced repression of translation (SIRT). Plants over-expressing BZIP11 show severe alterations of plant growth and development, reduced seed set and viability.
Subcellular Localization:
Nucleus.
Sequence:
MESSSSGTTSSTIQTSSGSEESLMEQRKRKRMLSNRESARRSRMKKQKLLDDLTAQVNHLKKENTEIVTSVSITTQHYLTVEAENSVLRAQLDELNHRLQSLNDIIEFLDSSNNNNNNNMGMCSNPLVGLECDDFFVNQMNMSYIMNQPLMASSDALMY
The following text describes a protein:
Function:
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for several aspects of mitotic spindle formation including the formation of the overlapping central spindle microtubules and kinetochore attachment. Required for the incorporation of tubulin subunits at the plus ends of kinetochore microtubules during poleward microtubule flux. Acts antagonistically to Klp10A and Klp67A to maintain metaphase spindle length. Also required for guidance of CNS axons downstream of Abl. May function to identify a subset of microtubules that probe the peripheral growth cone domain, where guidance signals exert their influence on cytoskeletal organization. Also required during oogenesis for the organization of the polarized microtubule network inside the 16-cell cyst that ensures oocyte differentiation.
Subcellular Localization:
Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cell projection, growth cone. Cleavage furrow. Note=Localizes to punctate cytoplasmic foci in interphase. Concentrates on spindle microtubules from prophase to late anaphase. Accumulates on the mid-part of the central spindle during telophase where it remains until cleavage. Subsequently appears at the periphery of the reforming karyomeres. Also localizes to the spindle remnant, cleavage furrows and the fusome of the 16-cell ovarian cyst. Localizes to the axonal growth cone within neurons.
Sequence:
MAYRKPSDLDGFIQQMPKADMRVKVQLAEDLVTFLSDDTNSIVCTDMGFLIDGLMPWLTGSHFKIAQKSLEAFSELIKRLGSDFNAYTATVLPHVIDRLGDSRDTVREKAQLLLRDLMEHRVLPPQALIDKLATSCFKHKNAKVREEFLQTIVNALHEYGTQQLSVRVYIPPVCALLGDPTVNVREAAIQTLVEIYKHVGDRLRPDLRRMDDVPASKLAMLEQKFDQVKQEGLLLPSALKNTNGNGVGLDEADNIGLRERPTRMIKRPLHSAVSSSLRPKPNVNDVTGDAGAVTMESFESSFEVVPQLNIFHAKDMDDIYKQVLVIISDKNADWEKRVDALKKIRALLILSYHTQPQFVAVQLKELSLSFVDILKEELRSQVIREACITIAYMSKTLRNKLDAFCWSILEHLINLIQNSAKVIASASTIALKYIIKYTHAPKLLKIYTDTLNQSKSKDIRSTLCELMVLLFEEWQTKALERNATVLRDTLKKSIGDADCDARRHSRYAYWAFRRHFPELADQIYGTLDIAAQRALEREREGGGGGGTGTGTGTAPETRRTVSRIGRTPGTLQKPTPSMRSISAVDTAAAQRAKVRAQYTLYSRQRKPLGPNNSNQASMTGAAASGSLPRPRLNSNSGGTPATTPGSVTPRPRGRAGVSQSQPGSRSTSPSTKLRDQYGGIGNYYRGATGAIPKKASGIPRSTASSRETSPTRSGGGLMKRSMYSTGAGSRRTPERNNPVRPSAAARLLAQSREAEHTLGVGDDGQPDYVSGDYMRSGGMRMGRKLMGRDESDDIDSEASSVCSERSFDSSYTRGNKSNYSLSGSHTRLDWSTQRAPFDDIETIIQFCASTHWSERKDGLISLTQYLADGKELTQQQLKCVLDMFRKMFMDTHTKVYSLFLDTVTELILVHANELHEWLFILLTRLFNKLGTDLLNSMHSKIWKTLQVVHEYFPTQLQLKELFRIISDSTQTPTTKTRIAILRFLTDLANTYCKSSDFPSDQSQACERTVLKLAQLAADQKSMELRSQARSCLVALYNLNTPQMTLLLADLPKVYQDSARSCIHSHMRRQSQSCNSGANSPSSSPLSSSSPKPLQSPSVGPFASLQSHHHQLSISSTSPRSRQSSVEQELLFSSELDIQHNIQKTSEEIRHCFGGQYQTALAPNGFNGHLQYHDQGQQDSCASLSSNSKTQSSANTTQSNTPESATMRLDNLERERTTQNAKSPTDDAKVITVSINMAENGELILASNLMESEVVRVALTLTKDQPVELLQTSLTNLGICIKGGNCELPNKHFRSIMRMLLNILEAEHTDVVIAGLHVLSKIMRSNKMRHNWMHFLELILLKIIQCYQHSKEALRDIDSMIPRIAPSLPLDLSINIVNPVIATGEFPTNLCAIKILLEVTEHHGSEITDAHLDIVFPNLARSADDTQSMVRKAAVFCIVKLYFVLGEEKVKPKLSVLNPSKVRLLNVYIEKQRNCISGGGSSTKNSSAASSS
The following text describes a protein:
Function:
Member of the two-component regulatory system TodS/TodT involved in the regulation of toluene degradation. Phosphorylates TodT via a four-step phosphorelay in response to toluene. Can also be induced by benzene and ethylbenzene.
Subcellular Localization:
Cytoplasm.
Domain:
Toluene binds to the N-terminal PAS sensor domain but not to the C-terminal PAS domain. The two PAS sensor domains may sense two different signals.
Sequence:
MSSLDRKKPQNRSKNNYYNICLKEKGSEELTCEEHARIIFDGLYEFVGLLDAHGNVLEVNQVALEGAGITLEEIRGKPFWKARWWQISKKTEATQKRLVETASSGEFVRCDVEILGKSGGREVIAVDFSLLPICNEEGSIVYLLAEGRNITDKKKAEAMLALKNQELEQSVERIRKLDNAKSDFFAKVSHELRTPLSLILGPLEAVMAAEAGRESPYWKQFEVIQRNAMTLLKQVNTLLDLAKMDARQMGLSYRRANLSQLTRTISSNFEGIAQQKSITFDTKLPVQMVAEVDCEKYERIILNLLSNAFKFTPDGGLIRCCLSLSRPNYALVTVSDSGPGIPPALRKEIFERFHQLSQEGQQATRGTGLGLSIVKEFVELHRGTISVSDAPGGGALFQVKLPLNAPEGAYVASNTAPRRDNPQVVDTDEYLLLAPNAENEAEVLPFQSDQPRVLIVEDNPDMRGFIKDCLSSDYQVYVAPDGAKALELMSNMPPDLLITDLMMPVMSGDMLVHQVRKKNELSHIPIMVLSAKSDAELRVKLLSESVQDFLLKPFSAHELRARVSNLVSMKVAGDALRKELSDQGDDIAILTHRLIKSRHRLQQSNIALSASEARWKAVYENSAAGIVLTDPENRILNANPAFQRITGYGEKDLEGLSMEQLTPSDESPQIKQRLANLLQGGGAEYSVERSYLCKNGSTIWANASVSLMPQRVGESPVILQIIDDITEKKQAQENLNQLQQQLVYVSRSATMGEFAAYIAHEINQPLSAIMTNANAGTRWLGNEPSNIPEAKEALARIIRDSDRAAEIIRMVRSFLKRQETVLKPIDLKALVTDTSLILKAPSQNNSVNLDVVADDELPEIWGDGVQIQQLIINLAMNAIEAISQADCETRQLTLSFSGNDTGDALVISVKDTGPGISERQMAQLFNAFYTTKKEGLGMGLAICLTITEVHNGKIWVECPPAGGACFLVSIPARQGSGT
The following text describes a protein:
Function:
May act as a regulator of the protein kinase A (PKA) during embryonic development.
Subcellular Localization:
Golgi apparatus. Cytoplasm.
Sequence:
MMEESGIEATPPGTPPPSTAGSTAASATPVSLALSSPLATPSMSSPAYSPPLPAAVAPLPPPIMTSATPSFVPSAAVSTIAPPLAPAPAPVTSSAFSTSLPQFSAPPPLSSTSGSGLSVPPTGPPISGFSLSSTYDITRGHAGRAPQSPLMPSYSAPPVTGVLADPITQQAPFSSPLASGTGSGSSITFPEEHEDPRVSAAQSGAPTGGLWGFIKGVAENPMVKSVLDKTKHSVESMITTLDPGMVPYIKTGGELDIVVTSNKEVKVAAIRDAFQEVFGMAVVTGEAAQSNIAPQPVGYAAGLKGAQERIDSLRRTGVIHEKQPAVSVESFIEELLPDKWFDIGCLIIEDPVHGIHLEAFTQATPVPLQYVQQAKSLTPQDYNLRWSGLLVTVGEVIEKNLLNISRTDWHAVFTGMSRRQMIYSTAKALAGMYKQHLPPRTV
The following text describes a protein:
Function:
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine (By similarity). Important for virulence.
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Domain:
The C2 domains have an essential, but non-catalytic function. They may facilitate interaction with PstB2 and are required for lipid transport function.
Sequence:
MRSSGYLNSNNGSSSSLESTNVNKSTDKNQLYLKVVCNCATDLVPQDTTGTGSESKKAYSSSKSINPVLVVQLNNTIKSTSKKLNTNQPSWNDELYMPLKNQDDSSLLIFSVWDKHTRYKNYLGELRLNVKDIFVDNGNFVDKTELKWYHLNSNTKYHSFVTGSILAGFELVIKNKKKRFHSSYNDKFQQLSIDSDVESAFKKWLSSLTKPTIYSVNNKINPNDQGFYDDELVNEFELESVLTERSKKSHLNVPGGNGLLSVPGDDCHDAGSFSDASFLSDGGYASDASANLFDQKETSSDSKKSRIKSKMRLRRSKQEYENFELASRQVLGVVFIEIVSCEDLPPYKNFTRTSFDMDPFVVVSFGKKTFRTGWKRHTLNPVFNERLAFELLPHESNFSIQFLVLDKDHFSFHDNVAHISLPLRTLTEYATAKPTEGDSSDVNTSDSTSFSQTGNGFTTEDTEFPENDSVQIIENETPSNKQSRKRYLSRKKVVGTQLDLKKFKAMSLSLQLHDQKYIGKYAPKLKIRVRFETYTELRKKFWRVLLEESNSTPENRDSCDYIELISLLDTLGCVNSDELVELFYSNLGKSSWGGDLLTFDEIIDQMETYVNQNVESGKVKIFEFEKCPICNEKRVSKKQDLDIITHFAICASKDWSVVGKLLSSSYVTPTQATKKWFTKALIKLTYGKYKLGGNSANILVQDRMTGIIVEEKMSVYVRLGIRLLYKGLDKARSKRVRILLKNMSIKQGKKFDAPQSKSDIASFIKFHKLDLDECEIDDPSQFATFNDFFYRKLKPGAREIEDEKNSKIVTSPADCRSVVFESIDKATQLWIKGAGFTIPKLIHNDHSMRVSSYTLGIFRLAPQDYHRFHSPVDGVIESIKHIDGEYYTVNPMAIRSELDVFGENVRTIVTIKTKDFGNIYFIAVGAMMVGSIVLTKDTGYEISKGEELGYFKFGGSTVLLLIESDKFKFDTDLVKNSSSGLETLLRVGQSIGHSPDVEEYKRDHISFDKLDKSKQLRLIRVLTGGDLKDKHKLSNWEATKIDMEDFQEIEDEEVFDKDMPDEDASIKSED
The following text describes a protein:
Function:
Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). Necessary and sufficient for endoreduplication and correct cell expansion. Controls meristem size by stimulating endoreduplication in the elongation zone.
Miscellaneous:
MISCELLANEOUS: FZR2 controls the induction of early rounds of endoreduplication while the remaining rounds may be mediated by FZR1 and FZR3; MISCELLANEOUS: FZR1 and FZR2 are functional homologs, and their functional divergence in root development arises from the different expression patterns.
Subcellular Localization:
Nucleus.
Sequence:
MEEEDPTASNVITNSNSSSMRNLSPAMNTPVVSLESRINRLINANQSQSPSPSSLSRSIYSDRFIPSRSGSNFALFDLSPSPSKDGKEDGAGSYATLLRAAMFGPETPEKRDITGFSSSRNIFRFKTETHRSLNSFSPFGVDDDSPGVSHSGPVKAPRKVPRSPYKVLDAPALQDDFYLNLVDWSAQNVLAVGLGNCVYLWNACSSKVTKLCDLGAEDSVCSVGWALRGTHLAVGTSTGKVQIWDASRCKRTRTMEGHRLRVGALAWGSSVLSSGSRDKSILQRDIRCQEDHVSKLAGHKSEVCGLKWSYDNRELASGGNDNRLFVWNQHSTQPVLKYSEHTAAVKAIAWSPHVHGLLASGGGTADRCIRFWNTTTNTHLSSIDTCSQVCNLAWSKNVNELVSTHGYSQNQIIVWKYPTMSKIATLTGHTYRVLYLAVSPDGQTIVTGAGDETLRFWNVFPSPKSQNTDSEIGSSFFGRTTIR
The following text describes a protein:
Function:
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), and autophagy. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE). This step is required for the membrane association of atg8. The formation of the atg8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt) (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MLTSFQQAVHKAYVKTVEKVTPTLSTSKFLEEGVLTPEEFVQAGDLLTDKCQTWTWESGDPSRNVSYLPKEKQFLLTRNVPCYNRVRTLENESKASKADEIQIEDDGEDSWVAPQPVGNQDDIEDEKVDISSLKIDDKKPNTTTTTTAKPTNNNNNNNDDEDEDEDGDIPDLDDFQDDNIIEEEDPAVLSKNNKTTTTTTANNNNNNNSENKVEDNDNILRTRTYDISITYDKYYQTPRVWLFGYDENRKPLKPEEIFEDISEDHAHKTVTIDSHPHLGISFAYIHPCRHAAVMKKLVDRQSENGKEPRVDQYLFLFLKFISVVIPTIEYDFTLEFDT
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MSANTTTNGERNIQQGNKEYAATFTQGHLVLPPSQKYAVLTCMDARIDPTAAFGIPLGAAHVIRNAGASARDAFRSIVISQQLLGTTEVLVVKHTGCGMLTFDNETAKSLVKKNKGDAAAKEVEDLDFFTFPELEAEVKKDVEWLRSKAVENGINFTGWVYEVETGKVRKVV
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
AGTIDAHHHIWLIFWFFSREPICPFEEKTKVERMVEDSLANGYQDSVTFDDVAVDFTPEEWALLDTTEKYLYRDVMLENYTNLASVEWEIQPRTKRSSLQQGFLKNQIFSGIQMTRGYSGWKLCDCKNCGEVFREQFCLKTHMRAQNGGNTSEGNCYGKDTLSVHKEASIGQELSKFNPCGKVFTLTPGLAVHLEVLNARQPYKCKECGKGFKYFASLDNHMGIHTDEKLSEFQECGKAVTASSHLKQCVAVHTGKKSKKTKKCGKSFTNFSQLYAHVKTHKGEKSFECKECGRSFRNSSCLNDHIQIHTGIKPHKCTYCGKAFTRSTQLTEHVRTHTGIKPYECKECGQAFAQYSGLSIHIRSHSGKKPYQCKECGKAFTTSTSLIQHTRIHTGEKPYECVECGKTFITSSRRSKHLKTHSGEKPFVCKICGKAFLYSSRLNVHLRTHTGEKPFVCKECGKAFAVSSRLSRHERIHTGEKPYECKDMSVTI