lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Endonuclease RNase P responsible for the 5' maturation of tRNA precursors. Also involved in the maturation of mRNA and small nucleolar RNA (snoRNA).
Subcellular Localization:
Nucleus.
Sequence:
MKLKKPSLPSSLLCAVPPCLSQIRLLIPRRVRVSSSTFANAKLVTLRNHTVNLHIYYCSMAGTDNRRSRHDDESPKNPNKKKKGNRNPEKSLLINLHSCSKRKDLSAALALYDAAITSSDIRLNQQHFQSLLYLCSAFISDPSLQTVAIDRGFQIFDRMVSSGISPNESSVTAVARLAAAKGDGDYAFKLVKDLVAVGGVSVPRLRTYAPALLCFCDTLEAEKGYEVEDHMDASGIVLEEAEISALLKVSAATGRENKVYRYLQKLRECVGCVSEETSKAIEEWFYGVKASEVSDNGIGSDIELLRAAVLKNGGGWHGLGWVGEGKWIVKKGNVSSAGKCLSCDEHLACVDTNEVETEDFVNSLVTLAMERKAKMNSCEPMADFSEFQEWLEKHGDYEAILDGANIGLYQQNFADGGFSLPQLEAVVKELYNKSGSKKQPLILLHKKRVNALLENPNHRNLVEEWINNNVLYATPPGSNDDWYWLYAAAKLKCLLVTNDEMRDHIFELLSNSFFQKWKERHQVRFTFVKGCLKLEMPPPFSVVIQESEKGSWHVPITSQDKEESLRSWMCITRQSS
The following text describes a protein:
Function:
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.
Subcellular Localization:
Membrane, coated pit. Membrane; Single-pass type I membrane protein.
Sequence:
MAPWGSAEGFPAWRSAQLLLLVVSCCGNSLHSIQLHNYSGCSWNVLQLILIYSCYLCEGRVEGNGALAEHSENVHISGVSTACGDIPEQIRSPSGTITSPGWPSEYPARINCSWYIHANPGEIITISFQDFDVQGSRRCSSDWLTIGSYKNIEGYRACGSSIPSPYISSQDHVWIRFHSDDSISRKGFRLAYFAGKSDEPNCDCDQFHCANGKCIPESWKCNNMDECGDNSDEEICAKANPPTISSFQPCASNQFQCLSRFTKLYTCLPESLKCDGNIDCLDLGDEIDCEVPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGFGDYVKIYDGLEENPRRLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQRDEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETHLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPITGRSSNIWNRIFNFARSRHSGSLALVSADGDDVASQSTSRDAERSNTHRSLFSVESDDTDTENERRDTAGAVGGVAATLPQKVPPATAIEATVGACGSSSAQSGSGGNTDSGREVTSIEPPGTSPARHQLTSALSRMTQGLRWVRFTLGRSSSVNQNQSPLRQLDNGVSGREEDDDVEMLIPVSDVASDFDMNDCSRPLLDLSSDQEPGLRQPYSATHHGVRSCNRDGPCESCGIVHTAQIPDTCLEATVKNETSDDEALLLC
The following text describes a protein:
Function:
Metallophosphoesterase that catalyzes the removal of a side-chain ethanolamine-phosphate (EtNP) from the second mannose of the GPI-anchor protein intermediate. Participates in the glycan remodeling steps of GPI-anchor maturation to allow an efficient transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDDTPVTKRRHLHAHVPNSPVPLQRDDRFSPSEGDSLKGLRCGHLLTFRKTALLVGVLVVLYNEVLVYYINKTSWKLPPGFSQFREDDQIVRLIIAGDPQIQGYQYEVGGFVGWITRLDSDRYLSKTFHLLLDMVQPDAVIFLGDLEDEGSVASDEEYSDYVQRFYQIFHVPTETKLILLAGDNDIGGEGADVITQEKMLRFEKNFAPLNEVVRVKNVDFIKVNLVTPYQEVPAVPQTQLVSQLSAPVRVLLSHVTLNAARLQTAAKILGSFMPQYAFSAHFHKYERTAFDITRIMKSAGLPYSADLGRKQLVTQEIQVPTCSYRMGTAEIGYIVVTIDQAGEMSSSVVWLPRRYVNLGVYVVYLIMVVLTWLIQQVCLPSKRHHMTGL
The following text describes a protein:
Function:
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
Subcellular Localization:
Cytoplasm.
Sequence:
MRRFIVTGLDLSGKNVVVRGDLFRHMARSLRLKIDTEVILADGKEAECTGVITAMGRDSLTVTISERRQIRGDGDGLWLTLCQGLPKGDKMELILQKSTELGVSEVVPFLAERSVPRISPEREQERLRRWQRVAEEAARQAGCPAVPRVQLARGLTEAVRGTDHDLKLLLWEDERTTTLAGVLAAAQTPKRIAVVVGPEGGFTAAEAAEAREAGFVPVTLGRRILRTETAGIALVAILQYLYGDLGSGPHPRPAPAQPIP
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
Sequence:
MTHQPSPVIHHHFAPAKINLGLSVLGVRENGYHDLHSLMVPLTVGDELEIRPAGALTLRVEGADLPTDERNLVYRAARAYLDAAGAAGGADLVLHKRLPLASGLGGGSSDAASTLLALAELYPAPDHRPVDLPALALTLGADVPFFLLGGAALAEGVGERLTPVDDLPPVHLVLANAGAEVSAGDAYRWLDETGDFSGKLRLEAMRLALARGVEVPYFNSLQAGVLARVPSVLTTLEALADAGLHSVLMSGSGATCFGLAHDAAQAQAAAAALAQRCPGWWVTAAQVRLPLSDNSGGRT
The following text describes a protein:
Function:
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MLIFEGKEISTDSEGYLKETTQWSEALAVAIAANEGIELSAEHWEVVRFVREFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCI
The following text describes a protein:
Function:
Transcription factor which controls spermatogenesis and sperm cell fate by regulation of sperm gene expression.
Subcellular Localization:
Chromosome. Nucleus. Note=Localized along the length of most but not all of the autosomal pachytene chromosomes; not detected on X chromosome.
Sequence:
MFGGDVSAASVLPSHPISGSCDGFQAEGSDHHHSTMTPFQESQRNVYQILYGHPANDDFPRPITPLQITIPEGDASPTVPVSCGVVNGKMHLNLFMCPGIHQPCIEVGNDLLSPKQFTIRGDKERQKDWKASIRVGRSSLRTHMEAMTIDFYEHMNRCSGKCQSRNYVNAPSEEVLQARKSKRTSEAGQLKYEIENEMAGKEADNDDNRKSAKKARGRPRGSVNKPRQMVKMEPQDDRFFEEFFIDAPPLQSMSSNEEPTSSNKESNECTPFNDILNCLQNDPMNFWSQMQQTGVIGHFCDDIIVSAINLKQSVMDNPVTPTTANMLTRTAFALGIPPVVVHRVQSIERNAYQQRKHDEMFNDIQSTLAEEHSVKYQPRTSSSSQESLHTAREFTEEKVEELIDVCKYDDYPESECLPGPSHIQ
The following text describes a protein:
Function:
Probable mannan synthase which consists of a 4-beta-mannosyltransferase activity on mannan using GDP-mannose. The beta-1,4-mannan product is the backbone for galactomannan synthesis by galactomannan galactosyltransferase. Galactomannan is a noncellulosic polysaccharides of plant cell wall.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MADLRMQFGIQWDLIKTPLIVPLLQLAVYICLAMTLMLFIERLYMGVVIILIKLFWKKPEQRYKWQPIDEDTESGNSSFPMVLIQIPMFNEKEVQFMFLNPTSFSCSKKLKRLNLFQVYKISIGAACNLSWPADRLVIQVLDDSTDVNIKDLIEKECRRWANKGVKIWYQIRESRGGYKAGALKEGLTHDYVKNCKYVTIFDADFRPEPDFLRRAIPFLEFNPKIALVQARWRFVNSDECLLTRMQEMSLDYHFTVEQEVGSATHAFFGFNGTGGVWRIAAINEAGGWKDRTTVEDMDLAVRAGLKGWKFLYLGDIQVNSELPSTFKAFRFQQHRWSCGPANLFRKMVLEIIRNKKVTFWKKVYVIYSFFFVRKIIAHMVTFFFFCIVLPVTILVPEVKVPTWGAIYIPCIITTLNSVGTPRSIHLLFYWILFENVMSLHRTKATFIGLLDAKRSNEWVVTEKLGDSVKNKKSNLKQIKPDPISKPFKFNLSNRIHLTELGFAVFLFFIGCYDFMYGNHRYFVYIFLQVVTFLIVGFGYVGTVVPS
The following text describes a protein:
Function:
Inhibits cell growth by regulating the Tor pathway upstream of the Tsc1-Tsc2 complex and downstream of Akt1. Acts as a cell death activator during head development.
Subcellular Localization:
Cytoplasm.
Sequence:
MKMEVLSVQNHIQGKFGVNKIKDWQASTAPLEEEEELTAGVNGNTAAGEGILDVDVVDGHPASVLHMRQHQALNTRPSATPPSAGGGGPLAGGGSVGMTTPKQATSPVAAASFEAPLSGGSAAAYHHAYMTNVLSSTAQQHHPLPASPLQSTACARFGAADNLDDVSASAVRELSQQLQAQLRDAKRRHLACTEVTLPNDLTQRIAAEIIRMSEREPCGERACTLFIEFESEPNKVKRIAYFKVDPDTVSIFELYLTLRQDKSGWSSLVPQFIKNLTRSNTINISPDFTLTKKKLYSSE
The following text describes a protein:
Function:
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
Subcellular Localization:
Membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MNILRPLSPHLPIYKPQLTSTFSISHRISGAFLATIVFFFYLLCLKIGLICFTYENFYQFFFYSSKLILISVEITALALSYHLYNGVRHLLTDFSGFFFLRIGRKRLK
The following text describes a protein:
Function:
Orphan nuclear receptor (Potential). Required for embryonic and larval morphogenesis and probably for seam cell positioning and migration.
Subcellular Localization:
Nucleus. Note=Localized in the nucleus from the one-cell stage of development onwards. Localizes to the nuclear periphery of all cells.
Sequence:
MIQSSSSISQDSLDLPSILSTFSADEPEDEPSPTAVKSTKPQRPTECLICGNSANGHHYDVASCNGCKTFFRRMCVSDRSFECKAKGDCFDLTKRKVPLKCRACRHQKCISVGMNPLAMEVDEKAASSSNFKKLVKRAQDLEPDDDCQVTAVVNKMQIVKPVDSIESKMQNITDMLVYLETKVERFRKSAYNPHWNEFSGLEYLLESECRIGFGDRFGPMPGWPLRRDQLGPPRLPKPPSPGKPRDSQHSQNIKQWFFYNLLTTVEYAKTFMFFHRLSSRDKLILTRHVALACTNLHISYSSIRRNLEVIIEPDGSEPMTFNDTHYSASVMSVAPLIRCQIKNIEYLLLKAIVLCNPAVPDLSAKSQEIISLERVKYADALFNYCLRSRSDGPPHFAQLIQIIDVLERQQRMQKDLHLLLVAPKVAKLPKDLVMRVIEDIMDS
The following text describes a protein:
Function:
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
Domain:
The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
Sequence:
MEDISEEQEFKYGEHSLQKIKVFKYSSTNASTYIYIHGGAWRDPSNTFDEMRPVLGIPNANLIGINYRLSPEIKHPEHLIDILRALRFVKQNFDVSQITLLGHSVGATMILQLLHYRQIIRDGLKHTHKDDLSSLDNLFAYVNDNVLLSQVIFLDGIYDVVELLKEYPDYASFVDDAFVSNKHFADSTQLSSANESLDLPFSLVSKDTKFLIYQSLEDDLLSMKQTHLLIDYLSSKNQGFTLHVGNWGKHEEIFGKYREIVFSGNVP
The following text describes a protein:
Function:
May modulate the internalization of amyloid-beta precursor protein.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MLGKDYMLAIILVNCDDDLWGDQSLEGEPGLPPGWRKIRDAAGTYYWHVPSGSTQWQRPTWEPGDAESGTRTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGEESHIQRMEPGAKCFAVRSLGWVEVPEEDLVPGKSSIAVNNCIQQLAQTRSRGQPPDGAWGEGQNMLMILKKDAMSLVNPLDHSLIHCQPLVHIRVWGVGSSKGRDSPISDPARDFAFVAGDKDSCMLKCHVFRCDVPAKAIASALHGLCAQILSERVGVSGDSPCCSLDPISPEDLPRQVELLDAVSQAAQKYEALFMGTLPVTKAMGMDVLNEAIGTLTTRGDRDAWVPAMLSVSDSLMTAHPIQAEAGAEEEPLWECPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAARGKAWGAQARARLRLKRTSSVDSPGGPLPLPLLKGGVGGAGAAPRKRSVFSFLDAFRLKPSLLHMP
The following text describes a protein:
Function:
Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide. N-deacetylation promotes PGA export through the PgaA porin.
Subcellular Localization:
Cell outer membrane; Lipid-anchor; Periplasmic side.
Domain:
Contains a N-terminal polysaccharide deacetylase domain, and a C-terminal domain required for PGA N-deacetylation that may be involved in binding to unmodified poly-beta-1,6-GlcNAc and thereby assists catalysis by the deacetylase domain.
Sequence:
MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPWPHNGFVAISWHNVEDEAADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGKPLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDELVDREYFATWQQVREVARSRLVELASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYETAAEYRERIRLDAVKMTEYLRTKVEVNPHVFVWPYGEANGIAIEELKKLGYDMFFTLESGLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKSPQRIMHIDLDYVYDENLQQMDRNIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTRSGVNIYAWMPVLSWDLDPTLTRVKYLPTGEKKAQIHPEQYHRLSPFDDRVRAQVGMLYEDLAGHAAFDGILFHDDALLSDYEDASAPAITAYQQAGFSGSLSEIRQNPEQFKQWARFKSRALTDFTLELSARVKAIRGPHIKTARNIFALPVIQPESEAWFAQNYADFLKSYDWTAIMAMPYLEGVAEKSADQWLIQLTNQIKNIPQAKDKSILELQAQNWQKNGQHQAISSQQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDLIRPEFSTAWYPKND
The following text describes a protein:
Function:
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MLLVLVVLIPVLVSSGGPEGHYEMLGTCRMVCDPYPARGPGAGARTDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDPGPPGPVGPPGEKGEPGKPGPPGLPGAGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD
The following text describes a protein:
Function:
Catalyzes the transfer of N-acetylneuraminyl groups onto glycan chains in glycoproteins. Conjugates sialic acid with an alpha-2-6 linkage to N-acetylgalactosamine (GalNAc) glycan chains linked to serine or threonine in glycoproteins. Sialylates alphaGalNAc- and Galbeta1->3GalNAc-O-Ser/Thr epitopes also known as Tn and T antigens.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MGSPRWKRFCFLLLAAFTSSLLLYGHYYATVDVRSGPRVVTSLLQPELLFLVRPDTPHPDNSHHKELRGTVKSREFFSQPSSELEKPKPSGKQPTPCPRSVAATAKADPTFGELFQFDIPVLMWDQHFNPETWDRLKARRVPYGWQGLSQAAVGSTLRLLNTSSNTRLFDRHLFPGGCIRCAVVGNGGILNGSRQGRAIDAHDLVFRLNGAITKGFEEDVGSKVSFYGFTVNTMKNSLIAYEAYGFTRTPQGKDLKYIFIPSDARDYIMLRSAIQGSPVPEGLDKGDEPQKYFGLEASAEKFKLLHPDFLHYLTTRFLRSELLDMQYGHLYMPSTGALMLLTALHTCDQVSAYGFITANYEQFSDHYYEPEKKPLVFYANHDMLLEAELWRSLHRAGIMELYQR
The following text describes a protein:
Function:
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Miscellaneous:
MISCELLANEOUS: The porphobilinogen subunits are added to the dipyrromethane group.
Sequence:
MRLKVATRGSRLSLLQTEEFLAQIKAVEPRVDFEIKIVKTTGDLVQDKPLFQIGVKGIFEKEVNLAVLKGEADIAIHSLKDLPSEISPGLVLAGFSKRTLPYDAVVSAVGYDLESLPKGALVGTSSVRRAEFIKSLRPDVRIEPLRGNVDTRVQKILQGKYDAAVMAAAGILRLYGESPPVKLSLLRPELLPPPPGQGIVAAVVREGEGWLIDLLKKASDPRATVEALAEREFLKNVGAGCHVAVGGTAFSRNGYIEFIAGYAASGKRFVVKLFGEDPVEVGRRAAEEIKRVAASVR
The following text describes a protein:
Function:
Transcription factor involved the regulation of plant development. Together with TCP14, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in developing leaf blade and specific floral tissues. Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1. Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers. Involved in gynoecium and silique development. Modulates the development of the different tissues of the gynoecium through its participation in auxin and cytokinin responses. Modulates the expression of the cytokinin-responsive genes ARR7 and ARR15. May repress the expression of the auxin biosynthetic genes YUC1 and YUC4. Acts as negative regulator of anthocyanin accumulation under high light conditions. Modulates the expression of transcription factors involved in the induction of anthocyanin biosynthesis genes. Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3. Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing TCP14 exhibit altered plant development and occasionally are lethal.
Subcellular Localization:
Nucleus.
Sequence:
MDPDPDHNHRPNFPLQLLDSSTSSSSTSLAIISTTSEPNSEPKKPPPKRTSTKDRHTKVEGRGRRIRMPAMCAARVFQLTRELGHKSDGETIEWLLQQAEPAVIAATGTGTIPANFTSLNISLRSSRSSLSAAHLRTTPSSYYFHSPHQSMTHHLQHQHQVRPKNESHSSSSSSSQLLDHNQMGNYLVQSTAGSLPTSQSPATAPFWSSGDNTQNLWAFNINPHHSGVVAGDVYNPNSGGSGGGSGVHLMNFAAPIALFSGQPLASGYGGGGGGGGEHSHYGVLAALNAAYRPVAETGNHNNNQQNRDGDHHHNHQEDGSTSHHS
The following text describes a protein:
Function:
Protease involved in the C-terminal processing of the chloroplastic D1 protein of photosystem II. This proteolytic processing is necessary to allow the light-driven assembly of the tetranuclear manganese cluster, which is responsible for photosynthetic water oxidation.
Subcellular Localization:
Plastid, chloroplast thylakoid lumen.
Sequence:
MEPLPLRSNFDLSPISSALPKPALLPLFSSRRISTSIRPHVSRKWSFYCASSLHTIKQTKPGPQSNAPDFFRSVGRGFIGFAAGAAALASLCCDSPAFAESVTVAFPVSRAREVNTVQRTLVEAWGLIRETFVDPTFNHQDWDLKLQQTMVEMFPLNSADAAYTKISAMLSTLGDPFTRIISPKEYQSFRIGSDGNLQGVGIFINVEPKSGQLVVLSCVEGSPAARAGIHGGDELIEINGERLDGLDSEAAARKLRGRVGTSVTVKVHSVQDSTSDSSIKEVKLPREYIKLSPIASSIIPHRTPDGRQTKTGYVKLSTFSQSAAADMANAVHEMETQGVHSYILDLRNNPGGLVKAGLDVAQIWLDGDETLVNTIDRDGNMLPISMVDGHAVTHDPLVVLINEGSASASEILAGALHDNGRAILVGHKTFGKGKIQSVTELHDGSALFVTVAKYLSPALHDIDQVGIMPDVQCTTEMLNSPKDESSASSLEADSCIMVAEHELDIQESRGTAS
The following text describes a protein:
Function:
Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation.
Subcellular Localization:
Nucleus speckle.
Sequence:
MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSPAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPSKTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPRPDNRDNRLEGNRGNSSSYRGPGQSRMEDTRDKGLVNRGRGQAISRGPGLVKQEDFREKMMGRREDSREKMNRGEGSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERVPPRRAGSRERGPPRGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKVYPYHRDEPPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMDRDMDRDVDRIGRPMDMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPSLSHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEINKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEEQKEEKKDAEEEESELVGDRPTTLNNKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYDTRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAEKALNRTKYI
The following text describes a protein:
Function:
Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene, and to one sequence in the araR promoter.
Subcellular Localization:
Cytoplasm.
Sequence:
MLPKYAQVKEEISSWINQGKILPDQKIPTENELMQQFGVSRHTIRKAIGDLVSQGLLYSVQGGGTFVASRSAKSALHSNKTIGVLTTYISDYIFPSIIRGIESYLSEQGYSMLLTSTNNNPDNERRGLENLLSQHIDGLIVEPTKSALQTPNIGYYLNLEKNGIPFAMINASYAELAAPSFTLDDVKGGMMAAEHLLSLGHTHMMGIFKADDTQGVKRMNGFIQAHRERELFPSPDMIVTFTTEEKESKLLEKVKATLEKNSKHMPTAILCYNDEIALKVIDMLREMDLKVPEDMSIVGYDDSHFAQISEVKLTSVKHPKSVLGKAAAKYVIDCLEHKKPKQEDVIFEPELIIRQSARKLNE
The following text describes a protein:
Function:
DauA is highly expressed within the cystic fibrosis (CF) lung, and it is required for virulence via the optimal production of hydrogen cyanide, pyocyanine, pyoverdine, rhamnolipid and alginate during biofilm formation. Involved in the catabolism of D-lysine and D-arginine. Under aerobic conditions, the arginine succinyltransferase (AST) and arginine transaminase (ATA) pathways are 2 major routes for L-arginine utilization as the sole source of carbon and nitrogen. The D-to-L racemization of arginine by DauA and DauB is necessary, before to be channeled into the AST and/or ATA pathways. DauA catalyzes the flavin-dependent oxidative deamination of D-arginine into 2-ketoarginine (2-KA) and ammonia. It also has dehydrogenase activity towards D-lysine, D-tyrosine, D-methionine, D-phenylalanine, D-ornithine, D-histidine and D-leucine as substrates.
Miscellaneous:
MISCELLANEOUS: In vitro, it is essential to include phenazine methosulfate (PMS) or iodonitrotetrazolium chloride (INT) as the artificial electron acceptor in the reaction to ensure DauA remains active with FAD.
Sequence:
MIEADYLVIGAGIAGASTGYWLSAHGRVVVLEREAQPGYHSTGRSAAHYTVAYGTPQVRALTAASRAFFDNPPAGFCEHPLLSPRPEMVVDFSDDPEELRRQYESGKALVPQMRLLDAEQACSIVPVLRRDKVFGATYDPTGADIDTDALHQGYLRGIRRNQGQVLCNHEALEIRRVDGAWEVRCDAGSYRAAVLVNAAGAWCDAIAGLAGVRPLGLQPKRRSAFIFAPPPGIDCHDWPMLVSLDESFYLKPDAGMLLGSPANADPVEAHDVQPEQLDIATGMYLIEEATTLTIRRPEHTWAGLRSFVADGDLVAGYAANAEGFFWVAAQGGYGIQTSAAMGEASAALIRHQPLPAHLREHGLDEAMLSPRRLSP
The following text describes a protein:
Function:
May be involved in the maintenance of both the function and the viability of sensory neurons, including photoreceptors and olfactory neurons.
Sequence:
MVDILGERHLVTCKGATVEAEAALQNKVVALYFAAARCAPSRDFTPLLCDFYTALVAEARRPAPFEVVFVSADGSSQEMLDFMRELHGAWLALPFHDPYRHELRKRYNVTAIPKLVIVKQNGEVITNKGRKQIRERGLACFQDWVEAADIFQNFSV
The following text describes a protein:
Function:
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
Sequence:
MINVEGENATVEDTASEVIAFKMSAISKGYYSDKYMKYFAGDILYGSQLPHQNFGTFIRSYMIRYVVKSFFDKFGPKSQVVSLGSGFDTLYWRLRDENIQFSKFIEVDKQFVVAKKQKYLENQVFQPLDNYILCDLDLNLEESTNVLNTLLIPDLPTLFIDEFSLIYLQPQVIQRLLKFFAGKGAFISYGMTNLGDDFGDLIKEGFNDMGIPLYGADFAQSTEEFITKALDIGFECADAQNAVFVVKHKIPIEERKRISRLEYFDDPHEVDFILSHYAFYAAGSEYFIKDLLN
The following text describes a protein:
Function:
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MKKYVALFGSCMFLVAFFSMYLMLDQLNLHGSLRSRVSMEMGQTELDFIKDKMENLEIDIHHNQQIIDEIRNSVKQIIGGENMSKYIPVQRNMSPLVEEVQDSPVQAKIETGDCSFVERQGEHRDDVQMLDVLDILPFDNPDGGVWKQGFDIHYTDRDWDNQPLKVFVVPHSHNDPGWIKTVDRYYLDQTQHILNNMVDKLKVDPRRKFIWAEISFFSMWWDNIDAEKKEAVKKLVENGQLEIVTGGWVMSDEAITHYYAMIDQMIEGHEWIKRNLGVKPRSGWAIDPFGHSPTMAYLLKRMGLQNMVVQRVHYSVKKQLAKEKQLEFMWRQNWDHGASSDMLCHMMPFYSYDVPHTCGPDPKVCCQFDFKRLPGGRVNCPWKVPPVPINDNNVAERAKLLLDQYRKKSKLYRSNIVLIPLGDDFRYDKAIEWDQQYGNYQKLFDYMNSQTNWHVEAQFGTLSDYFDAMWDRAGLQPGSPGLGYPVLSGDFFSYADREDHYWSGYYTSRPFYKNLDRVLEAHARAAEIIFSLALAHSRHIDVPSFPAKNAYQMLIGARKSLGLFQHHDAITGTAKDFVVVDYGTRLLRSIMDMKRVMIDSAHFLMSEDKTQYDPETTTTFFDMDEKRINHDALPEKPILQLTHQTKEVVFYNSVAQARHEVVRLRVSSSTVEVQDASGKVIPSQTNLVWTAAQDSSTTEYELVFIVNVPPLGLSKYLIRDAGSEVNNPYNAPSQITLYNTGSPDSSVRGVFHISRPISDNRDFTIENSRLRAKFSGTTGLLQSVTTVKDGKETAMSVEFLMYGTRETKKDKSGAYLFLPDGEAKTLDTNGKAVIRVIRGKILSEVHVLMKHVEHVITLHRSPGIDGWSLEISNIVDIRDQRNRELCMRLKTDVKNSNEFFSDLNGFQMQRRKTLSKLPLQANYYPMSTMAYLQDQDTRMTIHTAQSLGVGSLQEGWLEVMLDRRLNQDDNRGLQQGLLDNKRTPNQFRLLLERRHQRTSSPNGGSRQTGVDYPSLTSHSVSQLLNHPVYAFIRNKLPGEGPAGDVKLSGSVQPLVKALPCDIHFVNLRTVQAMDSPAPTQESVLLLHRKGFDCSFPANGLSCSTSGGKVQLEDLFRDLDLTDIKATSLSLMYDGQVLNSKATLQLDPMEINAYRIRLD
The following text describes a protein:
Function:
Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase. Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MSSATFVFIAWLITQVNCHAIELDENFHSLRDDGNWLVMFYAPWCGHCQRLHPTWDDVSRELSETEIKVGKLDATKYSDLAQELGIKGFPTIKFFKDSNSSFDHYGGRTTDAIIGFARRAQGPSLRTLHSPGHYKDAKRKHKLEVFFLLVTDNSDNEDGKLVMEKYKNISDEKVLEGYFYTGNSRIIPDDIKTKIQNYPQLIVYKDSSQYLYEGDLESMWKWINEERFLFFPKVDEISFYETTTSGKLVVLLAIDEDYDNYKEHLKLSNIARLVAWEKREKYHNYIALPFLLVYNASDGIYYLPDQAPLSMTKESFASFLEKVIAKEDIVGYGGYSFIQKVHRVIWNIYSTVKDIWDAQPILALVFFLLPTLLICFVCYNMCTMEESDEGTDEFEDEERVEGEEDKLR
The following text describes a protein:
Function:
Required for pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MALQTSGRHYDSAMERVLQMNIVGSEYYKELNSIKNHLEVIDEIYNQVEHVEPWMSGNARGSSTAFCLLYKLFTLELNIKQVQDLITHEDSPYIRAVGFLYLRYIADPKTLWDWCEPYLEDDEKFAPGINGKMVTMGLYVRDLLLELYYFDTIFPRIPVPVARQITANLESRGLPTKGLGAGGAGGKTARGAEGESRRPPSVKAALSVAFGQRAPHRSGAREAATADRVRGSSARLDEWDDVPAKPRDRSRDTRDKERSPLMPVARERSRDRKDERERSIDRRAEREKSARRERSPERRKERESSRDRRSDRERESRRDRERSRDRRVEPERVRDRSRDRRDDRDRERRPERSPERNLRREDDRGRDRSRERGVDRTKEAKRDRSRDRDRDSRKERGRDRSRERKDERGRDRRDRSRERGDRDKERHRDRSKERMKERDEGGRKEELDPEKDSHRNGRGSDREDRDRDGKRRDREHEKERDGDRKRPRTEEEGQEEDGQPSGGEGKDRLTDTERPLRDAPARTDVEETQQPGADEEGEEGEIEVHNDGDSKNASSTPDAPKEPEVGT
The following text describes a protein:
Function:
Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.
Subcellular Localization:
Nucleus.
Sequence:
MEAADLLPLLEQLDDNFDDLEEALKPILESPVLETSKKLPVLDKAKFHVLVTYALESLIFSYLRLHGVNAKEHPVFRELIRVKQYFGKIQALETEPEQRAMTLDKEAAGRFIKHGLAGNDKLDMKRKEQEAKEKARAQLRAALLAKKAAASETSSRNRTSSSDSESESDNEASDSEKSMIAGSEQLGNPLETTEPEDSQEVKKKKDNNKHETSKAIRKRMKRSKEEQQERNKERRQKKMEARRAAKAK