lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity).
Subcellular Localization:
Cytoplasm.
Domain:
ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site (By similarity).
Sequence:
MAHRLPTRWDIKWEEELLKLWEKEGRFKTKISGSRPVFVIDTPPPYLSSNRPHIGQTASYAHFDMIARFLRMRGVDVIFPFYLDRNGLPIEVQVEKKYGVVAHEIPREKFIKMCKEELDSYEGEFVSSLRRWGLSFDYWPNGTDSPEYRRMTQKTFIELWHKGLVYEAERPTPWCPRCRTALAEPEIEYREEETYLNYIKFKVKETGEDIIIATTRPELLPATVAVIFHPDDSRYTRLNGMHAVVPPEGQVVPILPHKAANPNFGSGLVMISTFGDTRDLMIVNELKLPIRIIIDEGGRIKTGKYAGVSIREARAKIIEDLKNAGLLVKQERLVHNVPVCWRCKTPLEIIVTRELFIKQIEFKEKLIELAGKMEFKPPEYRQVLIDWIKSLELDWPVSRRRYYATEIPIWWCAKPNGERVPLLPKGGEYYVPWRDEPPPEVKEACKDGRLEGDTRVFDTWFDSSISWMYASGVTKDFNAFSKVYPHSIMRPQGYDIIRTWLYYSLLRAYLLYGDVPFRYVRINGMGLDEKGEAMHKSKGNVIDLLAPVEKYGADPVRFWAAAAGRLGTDYRYNENVIREGKEFLTKVWNISRFVLSFPEPQQKPQLAPVDRALLARLYDVAKKVITAYSEFDVYEPAHALYNFIWHEFADHYIELVKSRAYNREGVFTEEEQRAAIWTLYTAWRYSLKLLAPIMPFVTDKIWREAYGRSIHDEMIEDPPEEWKEGDQALFHLVKKINSAVWRYKNRRGMSLADRLDAVLYVSELAMQAAKDLKYMHKVSDVRPGRGAEQIDDEGLVWLG
The following text describes a protein:
Function:
Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels.
Sequence:
MSGNGNMGSTEANPTPGRFSHCTLLANVDAYNPDTLDLYQDPEANRYWFACFKDMVLKFERQAMASQSKDASAAARAQSFREHCAEMLVQLQEGTRETPSLGIRNLLEVIESALRKFGFDDPWKEQKTIENKASIGMLKPRLQQLDSIASRREKWTEIVRGVLAGNMFDWGAQAVTKILETNNGFGLQQALDRIQKRPWLIDDLDGWLDRMEHDPPHRCATIFTDNAGIDFVLGIVPLVRELLKRKTKVLLCATINPAINDITYSELTKAIADCCEECDILRDAYSKEHRLLLFGNDQIGPCLDFRVLSKDLSDAIEQNDVDLLIIVGMARALHTNLYAKFACETFKLAVVKNEWLAKRLGGETFSVVCKYER
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Sequence:
MADEEPVDPKKYLEERCKPQCVKPLYEYEKCIKRVEADDTGHKHCTGQYFDYWSCIDKCVAPKLFEKLK
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MRGSDAMATHASRWRPPQNPAAVRKYSNETAAPQPPAKIIMEDHSLAEVFRRSAAFQRILAYVQGCSEAVESTPNHQRLSATVDDCDDTVRYLVTDYLPRLHDIVTAIPLEDMAQQRFGNRAKRVFHARLEETVVADMEKLVRTFPTSAGRSEEAITDMATEVAAYVMDSFGNATRLDYGSGHELHFFIVIMICLEEHGDGGGSLKDEPAVLVPLEVPPPPPVPPMERAEVRKRRQDYIFYIFHEYMRLVRRLQKRYSLEPAGSHGVWGLDDYHHIPYIFGGAQLINAEVQPVKPAAGQEAMLVLPKHICDRAKVEMLKDSYLYFSMIAWILENKTGPFHEHSNMLYNISGVEHWSKIYSGMVKMFAAEVLAKYNVSQHLLFGRHLPWNTKTM
The following text describes a protein:
Function:
Coordinates organism morphology with cellular differentiation during development. Negative regulator of sporulation, synchronizing encapsulation with culmination. May have an additional function in prestalk cells.
Sequence:
MDNNSTLNNITITVASSHNNTTTNSNNNNNNNNGSNSNNNNEQLNTLSNSITSLKSLNISGSGVITNNSEVNTPSEGNITPLPLLSLSDALSPLRELYSCLYVGDIRALMSNQYLKFEENEKIRILGFPEPHLEIDEKTQKYFSYQIIEFESDEDILSIAKSFEQYSQLILGRTPTQPVVIQECCFGLVLASIYFIKYELFSLPQAHDLIGYNDFFGTSKKHSHFEKVDSCTLINDITSYYYNNMSSKRKTTIFSNNISFTNLQTTTPPTTTTTTTTTTTTSSSNNSEQIESTSKNNSSGITSPTSIKPKNKVGLLKKLFNKMDKESSNNNNNKEKVEKIKEKKESKKEREAREAKEEKEREEREKEHQLALKNIPPAELYKHHMEQIQKIQKQQIAELNATSPDGGNDLSNGSNGSKNGNNNNNNNNSNNNNNNNNSNEPNSQHQNHNPITNLMDQELIENYDDGSDRMKNSKTIISPNFESLPDEYKTMVKTWDIKQESVDEHFEIILSLLHFHTKQRFYSSDPTNLPDKPKYYNVGNVCGNCTPPMILDPAGSGQMVVAKSFYKRPFDQICKKPTNEMKKLYTFREKVGKGGFGTVYLVRNNMDKSKSRIAIKKLPHVRKKEKKFNVKEIRVLEFTNHPNIITYYNSHMLHDEVWIAMEFMEGGTLAEASNQYPFQESNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSKGERIRMCGSPIWMPPEMIQQKQHGYTCDIWSTAICLLELANRNNKLRKNPIKTMFMVGSEGIKDPFEDPHKWSDEFHDIINKCLQMDPHKRPSAQELLKHPFIQLADNKKKMGKILSSIFLKSIVGI
The following text describes a protein:
Function:
Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.
Subcellular Localization:
Nucleus.
Sequence:
MGRVKLEIKRIENTTNRQVTFSKRRNGLIKKAYELSILCDIDIALLMFSPSDRLSLFSGKTRIEDVFSRYINLSDQERENALVFPDQSRRPDFQSKEYLLRTLQQLKAENDIALQLTNPTAINSDVEELEHEVYKLQQQLLMAEEELRKYEPDPIRFTTMEEYETCEKQLMDTLTRVNQRREHILSQDQLSSYEASALQQQQSMGGPFGNDVVGGWLTENGPNEAHLFDASAHSAMYETLLQGSSSSSNQNNIMGESNVSNHNGDMFQEWAQAYNSTTAHNPSTLFPPMQHQHGLVVDPNIEEIEIPVMKKDAQADHEVSDYDIRMPQLSSQ
The following text describes a protein:
Function:
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity); [Isoform A]: Nucleus. Cytoplasm. Note=Mainly nuclear.
Domain:
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
Sequence:
MTEVKSKETRAPSSARDGAVLLQAPPSRGEAEGIDVALDGLLYPRSSDEEEEEEENEEEEEEEEPQQREEEEEEEEEDRDCPSYRPGGGSLSKDCLDSVLDTFLAPAAHAAPWSLFGPEVPEVPVAPMSRGPEQKAVDAGPGAPGPSQPRPGAPLWPGADSLNVAVKARPGPEDASENRAPGLPGAEERGFPERDAGPGEGGLAPAAAASPAAVEPGAGQDYLHVPILPLNSAFLASRTRQLLDVEAAYDGSAFGPRSSPSVPAADLAEYGYPPPDGKEGPFAYGEFQSALKIKEEGVGLPAAPPPFLGAKAAPADFAQPPRAGQEPSLECVLYKAEPPLLPGAYGPPAAPDSLPSTSAAPPGLYSPLGLNGHHQALGFPAAVLKEGLPQLCPPYLGYVRPDTETSQSSQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKLNKMKVVRTLDVALQQPAVLQDETQSLTQRLSFSPNQEIPFVPPMISVLRGIEPEVVYAGYDNTKPETPSSLLTSLNHLCERQLLCVVKWSKLLPGFRNLHIDDQITLIQYSWMSLMVFAMGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLSMWQLPQEFVRLQVSQEEFLCMKALLLLNTIPLEGLRSQSQFDEMRTSYIRELVKAIGLRQKGVVANSQRFYQLTKLMDSMHDLVKQLHLFCLNTFLQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
The following text describes a protein:
Function:
Involved in the maturation of specific proteins in the endoplasmic reticulum.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPPLGTKRIKKCILYGQLIVLFTAFSSIYPQIHGLFGERGLVPVAPMLECEEESIFQCRLPLLRSVCQILHLSPSVGLQAFCLVGLFLSAFAIYKPRCQNIITYLILYLLYRTIYEAGGVFMYYQWDALLLESTVYVAILAWFDNGPADSIALFGIVSLLLRVVFMNGATKLLSKCPTWWNLTALNYHFESQPLPTPFAWYAHYFPQFFKQLATLQMNFIEILLPPLFLIPLIHVRYFVFFCQVLLTTLTLFTGNNGFFNYNILVLMVSLLQTPRVPIGASFLAAIVFAKIGFEVVYRLPYKILFEDDRLPSFALTLTHESFRKFMIYYIDVIVATMAIIFTIVNCYSMLKVGSSQNGRMKKWVHLAFVLCSVLFLGVYGNIPLLRMDEKLAQRTYEPPVVMTMYKTVNSWSVANSYGSYRQMTGTHGRPEIVIEGSHHIEGPWREIEFTSKPGKVSKRPRFISPHHPRLDMQMYYAAEGTYQQNPFFLSLVYHLMQNTTEVVNLIEDYPFKNRSEPMRFARAKLYMYHFTDIGDKNWWTRSFQEEYMPTFNKGNDALLNYLTEHKIINKRKSEFVNGPLGKYLKQCHRLTAGIDEIALISTMVVLVFFRKMYSYFFSAHRRNE
The following text describes a protein:
Function:
Snake venom phospholipase A2 (PLA2) that has myotoxic activity but no significant neurotoxicity. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Subcellular Localization:
Secreted.
Sequence:
NLLQFAFMIRQANKRRRPVIPYEEYGLYYM
The following text describes a protein:
Function:
Trypsin-like serine protease that plays an essential role in regulating the immune response by controlling all complement pathways. Inhibits these pathways by cleaving three peptide bonds in the alpha-chain of C3b and two bonds in the alpha-chain of C4b thereby inactivating these proteins. Essential cofactors for these reactions include factor H and C4BP in the fluid phase and membrane cofactor protein/CD46 and CR1 on cell surfaces. The presence of these cofactors on healthy cells allows degradation of deposited C3b by CFI in order to prevent undesired complement activation, while in apoptotic cells or microbes, the absence of such cofactors leads to C3b-mediated complement activation and subsequent opsonization.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MKLAHLSLFLLALHLSSSRSPSASDLPQEELVDQKCLLQKYTHRSCNKVFCQPWQRCIEGTCICKLPYQCPRAGTPVCAMNGRSYPTYCHQKSFECLHPEIKFSHNGTCAAEGKFNVSLIYGRTKTEGLVQVKLVDQDERMFICKNSWSMAEANVACVDLGFPLGVRDIQGSFNISGNLHINDTECLHVHCRGVETSLAECAFTKRRTELSNGLAGVVCYKQDADFPTSLSFQCVNGKHIPQEKACNGVNDCGDQSDELCCKGCRGNASLCKSGVCIPDQYKCNGEVDCITGEDESRCEEDRQQNIPKGLARSAQGEAEIETEETEMLTPGMDNERKRIKSLLPKLSCGVKRNTHTRRKRVIGGKPANVGDYPWQVAIKDGQRITCGGIYIGGCWILTAAHCVRPSRAHSYQVWTALLDWLKPNSQLGIQTVKRVIVHEKYNGATFQNDIALIEMKMHTGKKECELPNSVPACVPWSPYLFQPNDRCIISGWGRGKDNQKVYSLRWGEVDLIGNCSQFYPDRYYEKEMQCAGTRDGSIDACKGDSGGPLVCEDINNVTYVWGIVSWGENCGKPEFPGVYTRVANYFDWISYHVGRSLVSQHNV
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MMTNGRRDNNLLGVLLLVQRQDLQLPPMAAIVVDALDAGYYATTCPDAEAIVEDAMSRLHYTDPTLSPAIIRMLLHDCFVRGCDASVMIVPTPPLHHPATSSERTAVPNHTLRGFTAVDAVNARSTTRAAAVVSCADVLALMARDAVVLLGGARYDVALGRRDGTVSNPDEVDLPAPFAKLADVLDYFAARGFSAEETVVLFGAHTVGGAHCSSFRYRLTGGPGDGTMDETLRRDMLDECGAEELPLETDPAVFFDPDSPFAVDNNFYRQLMSNRTLLQVDQEAAVNPSTAPHVAYYAANPDAFVRRFSEVMAKLSNVGVLEGDAGEVRKLCSRYNDT
The following text describes a protein:
Function:
Component of an histone acetyltransferase complex.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MDIDKIIDERLTSLLKFPKTVTDATAQIYERDVKCNSFLKDIRMDIRGFTKGLKKMNADQKRNFIKEMNKKYDEAEKLSREKIVIAQNLYDVIDNEFQELGNTLQDIVPQNPKKNDDVDDDEPDTSDGSRRKSKKRKSADEPVHVPKLLTVDMPVDPNEPKYCTCDGVASGKMVCCDHSECEVEWYHYTCMGLDENYEIPDKVRWYCETCRPLFKNAPFQWNYERNEPPPNMPRQPPPKKRKSGKGNK
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MEAMGQGSMEATGRDGGREQTGTSSSYTISSTSGTVSTGYTSNGSHLSWISMEAARHFREMEGADEFVQPVKKTHKETEKQHTELAIARLKEMSIKTAREMKIEQIKSLSNEIFGAPWVKCSIQGADMSVLERWFNKLGVGWVLHVTAGKLEHTLDASSWIRALSEIMDAFCLTTSLFCGHEEAPNAQEAQEGAAVTEGKEEDITDLFQFASFTEQAMLQMLAFVDFIAAPNVTCQVFFTDQMMWVPAPYRKLHTLLRVRGALSRIRSSYSPPSVEAGRIRVQVFNVWSAKEGKVSEAIWSTMEEIRTRILESIDGSKGSSGTQTPQGSSDIDETTRSLMNYVTFLRDDHMLVNTIVSEAASLGKYVPRIGESEFGKIYTAQKLWKVPNPYLRKTLREAIIEKIIPGYKEYIENNHVTTPKFTPRNLEEMLQELFEG
The following text describes a protein:
Function:
Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor.
Miscellaneous:
MISCELLANEOUS: There are two sn-glycerol-3-phosphate dehydrogenase isozymes in E.coli: one is aerobic, the other anaerobic.
Subcellular Localization:
Cytoplasm.
Sequence:
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLARHYARTYGSNSELLLGNAGTVSDLGEDFGHEFYEAELKYLVDHEWVRRADDALWRRTKQGMWLNADQQSRVSQWLVEYTQQRLSLAS
The following text describes a protein:
Function:
Thiol protease which is required for parasite excystation and invasion of the proximal small intestine of the human host.
Subcellular Localization:
Vacuole.
Sequence:
MALSLLLAVVCAKPLVSRAELRRIQALNPPWKAGMPKRFENVTEDEFRSMLIRPDRLRARSGSLPPISITEVQELVDPIPPQFDFRDEYPQCVKPALDQGSCGGCWAFSAIGVFGDRRCAMGIDKEAVSYSQQHLISCSLENFGCDGGDFQPTWSFLTFTGATTAECVKYVDYGHTVASPCPAVCDDGSPIQLYKAHGYGQVSKSVPAIMGMLVAGGPLQTMIVVYADLSYYESGVYKHTYGTINLGFHALEIVGYGTTDDGTDYWIIKNSWGPDWGENGYFRIVRGVNECRIEDEIYAVYLD
The following text describes a protein:
Function:
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
Subcellular Localization:
Cytoplasm.
Domain:
Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
Sequence:
MRQTMTFIPTLKEVPADAEVKSHQLLLRAGFIRQTASGIYSYLPLATLMLRKIETIIREELEAIGAAELLMPALQPAELWQESGRWNDYGPELMRLKDRASRDFALGPTHEEVITALLRDEVKSYKRLPLTLYQIQTKFRDEKRPRFGLLRGREFIMKDAYSFHATSESLDEVYNLMHQAYSNIFTRCGLEFRSVIADSGSIGGNESKEFMALSDIGEDTIAYSDASDYAANTEMAPVLYMEKKSHELEKDLEKVATPDQKSITDIVGFLEVPIEKTMKSMLYQVDDEVIMVLVRGDHEVNDIKIKNALDATNVELVDPAVAVELLGANFGSLGPINVPENMRVFADNAVKDIVNAVVGANEDGFHYINVNPDRDFSVTSYFDLRMIQVGDLSPDGQGVIKFAEGIEVGHIFKLGTKYSEAMNATILDENGRAQPIIMGCYGIGVSRILSAIAEQSNDENGFVWDKQISPFDLHLIPVNMKSEEQVAFAETLYTSLQDAGFSVLIDDRAERAGVKFADADLIGLPIRITVGKKAAEGVVEVKIRKTGEMIEVRQDELLNTLPILFGDK
The following text describes a protein:
Function:
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis.
Miscellaneous:
MISCELLANEOUS: Present with 521 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Mitochondrion.
Sequence:
MGEHGGLVDLLDSDLEYSINRETPDKNNCLSQQSVNDSHLTAKTGGLNARSFLSTLSDDSLIEYVNQLSQTNKNNSNPTAGTLRFTTKNISCDELHADLGGGEDSPIARSVIEIQESDSNGDDVKKNTVYTREAYFHEKAHGQTLQDQILKDQYKDQISSQSSKIFKNCVIYINGYTKPGRLQLHEMIVLHGGKFLHYLSSKKTVTHIVASNLPLKKRIEFANYKVVSPDWIVDSVKEARLLPWQNYSLTSKLDEQQKKLDNCKTVNSIPLPSETSLHKGSKCVGSALLPVEQQSPVNLNNLEAKRIVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNENIHKYTKITDKDTYIIFHIDFDCFFATVAYLCRSSSFSACDFKRDPIVVCHGTKNSDIASCNYVARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKRLNIFNLILPISIDEAVCVRIIPDNIHNTNTLNARLCEEIRQEIFQGTNGCTVSIGCSDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGHSTLSRLESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDEESLKILYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLNEINKTTSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFGIIATEMKSLYRTLGCPPMELRGLALQFNKLVDVGPDNNQLKLRLPFKTIVTNRAFEALPEDVKNDINNEFEKRNYKRKESGLTSNSLSSKKKGFAISRLEVNDLPSTMEEQFMNELPTQIRAEVRHDLRIQKKIQQTKLGNLQEKIKRREESLQNEKNHFMGQNSIFQPIKFQNLTRFKKICQLVKQWVAETLGDGGPHEKDVKLFVKYLIKLCDSNRVHLVLHLSNLISRELNLCAFLNQDHSGFQTWERILLNDIIPLLNRNKHTYQTVRKLDMDFEV
The following text describes a protein:
Function:
May function as a transcription factor involved in cell differentiation.
Subcellular Localization:
Nucleus.
Sequence:
MHYRMNELNLSTVGIDQLTSSSVANSLTVSGSHLGLSGSPPHNTLPAPGLPVAIPNLGPSLSSLPSALSVMLPMGIGDRGVMCGLPERNYPLPPPPYPHLESSYFRHILPGILSYLADRPPPQYIHPSPLNVDGNSGLSVSNAPQSLDPFQPGGSVGLETGIVSLDSRSVGGHTGQSLHPSDGHEVQLDSGITMGSVSRVNSPIPSDGITEELAMEGVASEHRQLSNVPRSHEPLTVDGSLPPDAVGHASVLPLHSGSLELPVVMESEHHMATRSSMSESSLSDTIHTVAMDSNPVTVALSSSHQLSSLTSVSLHGGSISLEPVTVSSITPEVSMGGGHVDTGNLTFVPSTLQIDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFIPDNPIESRARLSLPKELALRQSVTGAEMGVWAQETIPVRTCFGPLIGQESQSLEVADWTDKSASHIWKMYHNGVMEFCIITTDENECNWMMFVRKARNPEEQNLVAYPHDGKIYFCTSHNVSPEQELLFYYSRDYARQMGLPEQPEFFVCHCGKECHSYADFKSHVNSHLPAEPLSSGVANGLTPTKERKWKCSMCSRSFISSSKLNVHFMGHMGMKPHKCEFCSKAFSDPSNLRTHLRIHTGQKNYRCGLCDKSFTQKAHLASHMAIHTGEKTLKCDFCEKMFMRRHDLKQHVLTHTRERRIRCPKCDKCFSRTGHLKKHLNSHEGRRDYVCEKCSKAFLTRYHLSRHLKICKGPSTAPLTPDTDEEEDSEDEELLGSDCVVFNTDLTVHT
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Sequence:
MSALPAVGDTVEDFTLPDETGTPRRLSELLADGPVVLFFYPAALTTGCTAEACHFRDLAAEFAAVGARPVGVSGDPVERQQEFAGRHTLGMPLLSDTDGAVRERFGVKRGFSLAPTKRVTFVVGQDRTLLEVVRSEIRMNTHADRALAALRAHRP
The following text describes a protein:
Function:
Promotes the tolerance to a range of metals, including cadmium (Cd), arsenic (As) and copper (Cu) and to oxidizing chemicals (e.g. diamide and tert-butyl hydroperoxide (t-BOOH)). May act as a chromatin remodeling factor for stress responses. Negative regulator of flowering, especially during drought stress, probably to prevent precocious flower development and subsequent low seed set. Repress the AP1 promoter in a SOC1-dependent manner.
Subcellular Localization:
Nucleus. Nucleus speckle. Note=Observed in a subnuclear speckling pattern, discrete parts of the chromatin of the nucleosome.
Sequence:
MFKEMNLNLKQMGNMIYEDPTRIQEEEDIVQEVSTTFSDEEDNSSSCSLSSSMCSDFTEDDDDDDVSSSSSNGPLEDLSDLMSHLPIKRGLSKFYEGKSQSFTSLGNVKSLEDLMKRGFKSRNYGAKRKSSRSTGGILDQSYKRVFSPKATISKKPNRTPSSVLSCLARRRH
The following text describes a protein:
Function:
Needed for flagellar regrowth and assembly.
Sequence:
MQSLYKVIKKSSVVRQGEEKIKTNYKKPVSLEIEKEKEIEEENSKKFIDSYENLARNILENARKKSEEFLSKAYAEAEVVEEEAFKKGHEEGFHKGSEEGKKSGYEEAYEAYIEKGKNAYEEMVQKSNKLLLDTEAQYNSYLKEKEEEVRNLVLTIVEEVLKHEVKDKSSMNEIIYEKLEESKKSATFIVKSNTNYYEEIKAKSEFWKNQLPYRGEIFVIEDISLKDGEVIIETEQGKVIASLDTALDKIKELLINEK
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Nuclear rim.
Sequence:
MHDSSWTEADILGVCSFLDIPKTKIDPLLQVDAFTSILIPLISKSKDYESIKNDRIVTEVNYEQQLRNSEKKLLQSNERYDLLEDERKLLENELSQIKEYLREKSSSYDTVLHDCSSLKSVNEALKQAQDQNLKQTAQLQNLLSDKEKEVEKKITIIKDLKDALASSTHQVLELQHTQQEKASLQTNYEFELQKLTQKNSILENNNTWLSRELQGVNDKLLSLHQEASLEKSQLSSQLSDAVLEKDALQRKVSSLSQQFTESNLRYQNIVAELSEMRKQYEFSQVSFEKEISSQKQISELWMEKCEDCSLRLKELQNSNGELEKLLEAAQSSFEEQLESHKEAEASLKSQINFLEKEVSSLESQLKLANERLRHYDEIEISDMSELKYSNLLNNSMKGFKGQSSVSDLYSERLYYKQKYEQTCQEVERLQRSYNHVMEEANLQHPLVKEQFKRFAHMQREIVAMSEQYQKSLEDCQKAKSRYEQLETLFKDKCTENKHYEQETKDLARQVQVLLHELDLCENGIVLGVDSRKKINSYVEKSLTEDETDTDQIISSRLVVFRNIRELQQQNQNLLSAVHELADRMEKDEKPDLDGAEIQEETLIKANETIDQLTKMLEEVSDQLRYSLKERDFFRSLVQENEKLLDMAPATPNSKLNTNLIEQTSYQRSLIRLEQLTNELESLKSISRNKEKKFEEAISSLQLEKSNIQLQLTSLTSERSLALEKLNDLEKSLVLSERSKDELDESYKSLQEQLASKKIEVQNVSSQLSICNSQLEQSNHIVDNLKSENLLLTSVKDKLKADLSNLESKLSSLQQDNFHMKAQIESSNQEYTATVDSMNSRILELSNDLRVANSKLSECSDDVRRLTLQNSFDLREHQTLVLQLQSNITELKQDITLQRTVRNQLEIQTTELKERLKFMEERQENLQSKLIAANKDTTQNPDNVEVEAISIELERTKEKLRMAELEKSNIQQKYLASEKTLEMMNETHEQFKHLVESEISTREEKITSLRSELLDLNKRVEVLKEEKESSSKELAKQLEDAVREKDSALSFKKDYEKIRSDADRVITSLKEDIEKERSLMKECHSNYESEIVSHGRTTQKLRDLRTEFDEVNTKYLKLKANFEQQHSGLSGAEKDWNIQRKAMEDEISSLKDYILGLENQNKLLHSQFDSLSQQITVLQQNSSENLNISANLEAVQDNDLRELVSYLRHEKEIMDNKYELTILDNRGLNQQVKSLQSTVDSLQLELNRLQSLPVSNDQTDTPIISGSQEVQLLYESNSVLRKDNDAKLGKIQELEKEVEKLNASLNPLQTEINELKAEIGAKTASLNLMKEYNSRWKLRFQSVLNKYERVDPTQLEELKKNCEALEKEKQELETKLQETAKETDTFKQQVNSLNEEVENLKKEVEQANTKNTRLAAAWNEKCENLKKSSLTRFAHLKQELTNKNKELTSKNAENEAMQKEIESLKDSNHQLQESASSDAEQITKEQFEQLKSEKERTEKELADSKNELEHLQSEAVDADGKTEISNLEKEIHELRSDKEGLVQQVQNLSAELAALREHSPTQGSLENADEIARLRSQLESTKQYYEKEKETEILAARSELVAEKEKTKEELENQLNEKSQRIKELEEQAQKNSSENTHDNIDDMIKQQVEEKLKENSANFDVKLKKVVAETEFRSKAKISVYEKKTRDLQNKITQLEETIENLNKQLSNPEKTDESTSSVTETKPVTSKPTASKADVGQNATEASSAKREPSGKSLSARLQGTGKQKGVQRPAVSRPVPMKPDSGKLSITGASKRIATSKNAAQNAKELSSTAKSGSLKRQRDDANKGGSSSNQKKAK
The following text describes a protein:
Function:
Small conductance calcium-activated potassium channel that mediates the voltage-independent transmembrane transfer of potassium across the cell membrane through a constitutive interaction with calmodulin which binds the intracellular calcium allowing its opening. The current is characterized by a voltage-independent activation, an intracellular calcium concentration increase-dependent activation and a single-channel conductance of about 3 picosiemens. Also presents an inwardly rectifying current, thus reducing its already small outward conductance of potassium ions, which is particularly the case when the membrane potential displays positive values, above + 20 mV (By similarity). Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization (Probable).
Miscellaneous:
MISCELLANEOUS: [Isoform 1]: Produced by alternative splicing events in which various combinations of the four 5' non-coding exons A, B1, B2 or C are joined directly to exon 3.2; MISCELLANEOUS: [Isoform 3]: Reduced calmodulin-binding; MISCELLANEOUS: [Isoform 4]: Reduced calmodulin-binding; MISCELLANEOUS: [Isoform 5]: Reduced calmodulin-binding; MISCELLANEOUS: [Isoform 6]: Reduced calmodulin-binding; MISCELLANEOUS: [Isoform 7]: Reduced calmodulin-binding; MISCELLANEOUS: [Isoform 8]: Reduced calmodulin-binding.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Cytoplasm, myofibril, sarcomere, Z line.
Domain:
The coiled-coil domaim mediates heteromeic assembly.
Sequence:
MSSHSHNGSVGQPLGSGPGFLGWEPVDPEAGRPLQPTQGPGLQMVAKGQPVRLSPGGSRGHPQEQEEEEEEEEEEDKTGSGKPPTVSHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESLCSFALKCLISLSTVILLGLVILYHAREIQLFLVDNGADDWRIAMTWERVSLISLELVVCAIHPVPGHYRFTWTARLAFSLVPSAAEADLDVLLSIPMFLRLYLLARVMLLHSRIFTDASSRSIGALNRVTFNTRFVTKTLMTICPGTVLLVFSVSSWIVAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQGRVRKHQRKFLQAIHQAQKLRSVKIEQGKVNDQANTLAELAKAQSIAYEVVSELQAQQEELEARLAALESRLDVLGASLQALPGLIAQAICPLPPPWPGPGHLATATHSPQSHWLPTMGSDCG
The following text describes a protein:
Function:
Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.
Sequence:
MYGASLLKRVSPLREAKRFYDNQMAYSERRIVGYSREQMFDVVSHVEKYHEFVPWCQKSTVSHEGPHSLLARLEVGFQIIKASYSSRVTLVRPAVVHSVCADPEGGLFRVLDTTWRFSSSPGDDSINTCRIHFDLSFEFRNSTHARITHLFFDKVVQQQVSAFLDRARTVHGPPSRSPSPPEILRYEA
The following text describes a protein:
Function:
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
Sequence:
MKRFRNLSVNKRKKHLDTAVPEIDNVEPQSKDDNVPINQKAKFKFRIGKTLFRTKSAKKSSSSNESERNSTIAENKNGPSSSLTDVQSNQDSPIQVNNSNFLNDSTQERSCQTDELSNGQAGNVQNITPKQHINGHAGGDQLHSSNYTCNNFTSQGTSENSPNENLYQLPSNDTHTNHSGKLSQLQEEDTVVPDSTDVYQTPESLDHGIMGATAAPVSPDVNHTFHTLTSLHVPPTMRKNTLTNEFKKLAQQGWYWGPLTRSEAEDKLNETPNGSFLVRDSSDERYLLSLSFRSFGRTLHTRIEHSSGNFSFYENNRMQSYDSVVDLIMDSVRDSQEAGIFCYSRTRDPLATTYPVRLIHPVSRLSQVRTLQYLCRFVIRQYTRIDHIESLPLPNPVKGYLNESYF