lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MHRKKVDNRIRILIENGVSERQRSLFVVVGDRGKDQVVILHHMLSKATVKARPSVLWCYKKELGFSSHRKKRMRQLQKKIKSGTLNIKQDDPFELFVAATNIRYCYYNETHKILGNTFGMCVLQDFEALTPNLLARTVETVEGGGLVVILLRTMNSLKQLYTMTMDVHSRYRTEAHQDVVGRFNERFILSLASCKKCLVIDDQLNILPISSHVASIEALPPQAPDENLSPAALELQELKESLQDTQPVGVLVDCCKTLDQAKAVLKFIEGISEKTLRSTVALTAARGRGKSAALGLAIAGAVAFGYSNIFVTSPSPDNLHTLFEFVFKGFDALQYQEHLDYEIVQSLNPEFNKAVIRVNVFREHRQTIQYIHPADAVKLGQAELVVIDEAAAIPLPLVKSLLGPYLVFMASTINGIFIVVRCSRTLHEVSLQESIRYAPGDAVEKWLNDLLCLDCLNITRIVSGCPLPEACELYYVNRDTLFCYHKASEVFLQRLMALYVASHYKNSPNDLQMLSDAPAHHLFCLLPPVPPTQNALPEVLAVVQVCLEGELSRQSILNSLSRGKKASGDLLPWTVSEQFQDPDFGGLSGGRVVRIAVHPDYQGMGYGSRALQLLQMYYEGRFPCLEEKVLETPQEIHTVSSEAVSLLEEVITPRKDLPPLLLKLNERPAERLDYLGVSYGLTPRLLKFWKRAGFVPVYLRQTPNDLTGEHSCIMLKTLADEDEAERGAWLAAFWTDFRRRFLALLSYQFSTFSPALSLNIIQNRNIAKSAPPVLGREHLEALFLPYDLKRLEMYSRNMVDYHLIMDLIPAISRLYFLNQLGDLALSAAQSALLLGMGLQHKSVDQLEKEIELPSGQLMGLFNRIIRKVVKLFNDVQEKAIEEQMVAVKDVVMEPTIKTLSDDLDEAAKEFQEKHKKDVGKLKDMDLSQYIIRGDDEEWNEVLSKAGQNASIVSLKSDKKRKLETKQEPKQSKKLKKSGNNRKDTKLKRKK
The following text describes a protein:
Function:
Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleoyl-CoA and other unsaturated long-chain fatty acid-CoA esters (By similarity). Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLRTSFQGVARLVRHKALYRSPCLLPRVHLASAFGSSTESLVARFCPEKTDLKDYALPNASWCSDMLSLYQEFLEKTKSGGWIKLPSFKSNRDHIQGLKLPFGLETASDKQDWRLFTRSIQLEGQGYEYVIFFHPSEKKSVCLFQPGPYLEGAPGFAHGGSLAALMDETYSKTAYLAGEGLFTLSLNIKFKNLIPVGSLAVLDIQVEKIEDQKLYMSCIAQSRDKQTVYAKSSGVFLQLQLEEQSQEQ
The following text describes a protein:
Function:
Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase. It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction (Probable). Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1-independent manner. Thereby, this secreted protein may indirectly regulate whole body energy expenditure. PM20D1 circulates in tight association with both low- and high-density (LDL and HDL,respectively) lipoprotein particles.
Miscellaneous:
MISCELLANEOUS: Overexpression in mice blunts high fat diet-induced increase in fat mass and associated weight gain. Free NAAs represent the biologically active form of these circulating molecules, and the circulating NAAs bioactivity is determined by plasma protein binding.
Subcellular Localization:
Secreted.
Sequence:
MAELLASLPAWAAVLLLFFATVSGSTGPRSRENRGASRIPSQFSEEERVAIKEALKGAIQIPTVSFSHEESNTTALAEFGEYIRKAFPTVFHSSLVQHEVVAKYSHLFTIQGSDPSLQPYMLMAHIDVVPAPEEGWEVPPFSGLERNGFIYGRGALDNKNSVMAILHALELLLIRNYSPKRSFFIALGHDEEVSGEKGAQKISALLQARGVQLAFLVDEGSFILEGFIPNLEKPVAMISVTEKGALDLMLQVNMTPGHSSAPPKETSIGILSAAVSRLEQTPMPNMFGGGPLKKTMKLLANEFSFPINIVLRNLWLFHPIVSRIMERNPITNALVRTTTALTMFNAGIKVNVIPPLAQATINCRIHPSQTVHEVLELVKNTVADDRVQLHVLRSFEPLPISPSDDQAMGYQLLQETIRSVFPEVDIVVPGICIANTDTRHYANITNGMYRFNPLPLNPQDFSGVHGINEKVSVQNYQNQVKFIFEFIQNADTYKEPVPHLHEL
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
LANNCIPDHLADATHLEKNASLSSSWIDATLLFLLDGFQKWDAVHYTHIAAHGYNHPRLLAFQPLLPWLLRQFDLWAISPILGNLVHTYTRILLIGTTFNISAFAISAILLYKLSYKVLQNQILAIVSVTMYCINPASIFMSSLYTESLYACCSFGGMLCWQYPTNLTGYLLGTLAFTLAVAVRSNGMVLIGFVGYTLLLYRLKTASSGRLFLFEIIYYACQTIVLLLPFAIAILSPFYMFQSYGMRKFCNSSHQVEPLPWCNKDLSIPYWEVQRKYWNVGFLRYYQLKQIPNFILAAPMVTLCIFAIRKYLHCWNSLYASFLASSQLPITFGNPAMFVYIIHVLFLTIFGLTSMHVQVITRLIASSSPVIYWFTAYSIIQGIKHRSKDPSGRLAVIYFLTYSIIGTVVHSNFYPWT
The following text describes a protein:
Function:
GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. Involved in the expression of cytochrome c oxidase subunit 1 (COX1). Works in association with the small subunit of mitoribosomes.
Miscellaneous:
MISCELLANEOUS: Present with 768 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MNSASFLQSRLISRSFLVRRSLKRYSGLAKPYTFQQPTIYALSTPANQTSAIAIIRISGTHAKYIYNRLVDSSTVPPIRKAILRNIYSPSSCSVKPHDQKESKILLDTSLLLYFQAPYSFTGEDVLELHVHGGKAVVNSILKAIGSLHDRSSGKDIRFALPGDFSRRAFQNGKFDLTQLEGIKDLIDSETESQRRSALSSFNGDNKILFENWRETIIENMAQLTAIIDFADDNSQEIQNTDEIFHNVEKNIICLRDQIVTFMQKVEKSTILQNGIKLVLLGAPNVGKSSLVNSLTNDDISIVSDIPGTTRDSIDAMINVNGYKVIICDTAGIREKSSDKIEMLGIDRAKKKSVQSDLCLFIVDPTDLSKLLPEDILAHLSSKTFGNKRIIIVVNKSDLVSDDEMTKVLNKLQTRLGSKYPILSVSCKTKEGIESLISTLTSNFESLSQSSADASPVIVSKRVSEILKNDVLYGLEEFFKSKDFHNDIVLATENLRYASDGIAKITGQAIGIEEILDSVFSKFCIGK
The following text describes a protein:
Function:
May function as an integrase.
Sequence:
MEHFIDTYLYELRKVRDEKTIKKKEYLLKHLQDYSEDLPAFDQSEIFSFYEYLKNKNLKETTIRDILKEVRLFYEWLQEQGLNLKFDEKALKKLFQSKKSQEALKSKKKYYSDDEINLILNAIRGAVEGISTKHPIYYILTIFLLCSGLRISEAVKVRKKDFEVKRILTEEGEEKEVWFVKVREGKFGKERKALIYFFRPEWKRIFEERLKKLKPEDFFFTYAVKYPKSVKVFTLTDKTAKWFYWKLEKELREKGYEIEVNAHRFRNTYITKLATKGFPVNLIADWVGHSKISTTMDVYMEAEREKQLEAILERI
The following text describes a protein:
Function:
Associates loosely with the viral DNA to form an outer shell around the nucleoprotein-DNA complex and links it with the capsid by binding the endosome lysis protein. Dissociates from the viral genome during entry. Might be involved in nuclear capsid assembly of the viral particles through its association with NPM1/nucleophosmin.
Miscellaneous:
MISCELLANEOUS: All late proteins expressed from the major late promoter are produced by alternative splicing and alternative polyadenylation of the same gene giving rise to non-overlapping ORFs. A leader sequence is present in the N-terminus of all these mRNAs and is recognized by the viral shutoff protein to provide expression although conventional translation via ribosome scanning from the cap has been shut off in the host cell; MISCELLANEOUS: This protein is only encoded by mastadenoviruses, and may therefore play a role in mammals tropism.
Subcellular Localization:
Virion. Host nucleus, host nucleolus. Note=Located inside the capsid (core). Present in 157 copies per virion. Localizes in the nucleoli during infection, then translocates from the nucleoli to the nucleoplasm as the infection progresses and is finally incorporated into the viral particles.
Sequence:
MSKRKIKEEMLQVIAPEIYGPPKKEEQDYKPRKLKRVKKKKKDDDDDELDDEVELLHATAPRRRVQWKGRRVRRVLRPGTTVVFTPGERSTRTYKRVYDEVYGDEDLLEQANERLGEFAYGKRHKDMLALPLDEGNPTPSLKPVTLQQVLPTLAPSEEKRGLKRESGDLAPTVQLMVPKRQRLEDVLEKMTVEPGLEPEVRVRPIKQVAPGLGVQTVDVQIPTTSSTSIATATEGMETQTSPVASAVADAAVQAAAAAASKTSTEVQTDPWMFRVSAPRRPRRSRKYGTASALLPEYALHPSIAPTPGYRGYTYRPRRRATTRRRTTTGTRRRRRRRQPVLAPISVRRVAREGGRTLVLPTARYHPSIV
The following text describes a protein:
Function:
Involved in the synthesis of cell wall sulfolipids with activity towards mycobacterial trehalose glycolipids and eukaryotic glycolipids such as glucosylceramide and galactosylceramide (type I and II) but not towards eukaryotic 3'-sulfate galactosylceramide.
Sequence:
MNSEHPMTDRVVYRSLMADNLRWDALQLRDGDIIISAPSKSGLTWTQRLVSLLVFDGPDLPGPLSTVSPWLDQTIRPIEEVVATLDAQQHRRFIKTHTPLDGLVLDDRVSYICVGRDPRDAAVSMLYQSANMNEDRMRILHEAVVPFHERIAPPFAELGHARSPTEEFRDWMEGPNQPPPGIGFTHLKGIGTLANILHQLGTVWVRRHLPNVALFHYADYQADLAGELLRPARVLGIAATRDRARDLAQYATLDAMRSRASEIAPNTTDGIWHSDERFFRRGGSGDWQQFFTEAEHLRYYHRINQLAPPDLLAWAHEGRRGYDPAN
The following text describes a protein:
Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
Sequence:
MSAAQTAAATPAEQEEQRKVVEKFKALRDQQQDIAAEVTRIEEERREFGRVLEVIKDLEPDQKCFRLISDTLVEYTVKDVIPDLQNNIANLTIVSKQLNDQLVEKGKELNTHKTTHNIRLLTEKESAELRKAEALGQLPKA
The following text describes a protein:
Function:
May function as a negative feedback regulator of TOR function.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MHTTTKRRKAMDWLNFDPIPEVDRLFRFTCKHPTLHVHMTGSYGHMFVDISDLPASARHYLALMAASRHRCLSLMDHHRRKFLEKGGQQMWLLGIDWSYMKFRKLDYLNRMLCHRPWMIHWKNLAVLFARRTPDGGPAFFSVCSLHHAVGIMSMTHAMCTVICCIGLERRVDLTQDEIDFLNIDDLDYWEARMSAYFRKVPDRRPTEVEYLISELKKTEKGQTRPPAKMCAMTTETIESLISAPAATYSSNRKNYSPVLLLANIDENGEDIMEKEPPCNYPIYSHHRTFGYIDFRKRPEKDIPPFRVEEFGWDHVYNTMNEYTDTLTSRLDRMFDHIRTLTGNMPSGSSHASGDGEPPAAVNQNEIDTAAFREAIWNYTQGLYGVRVDDYDYSKINRVLDKGTKTFIKLAACYPHKLTTEFTRALPGFKDSEKIHVVMMVAMARFQASMFHYTRAVCNYNAMCLSKKGWRKPLD
The following text describes a protein:
Function:
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta. Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell surface.
Sequence:
MSHQILLLLAMLTLGLASSQHRDKVPCKKVDKEASCQGLGLLQVPSMLARDIEALDLSGNQLRSIPASPLGFYVALRRLDLSANEISSLQPGAFQALPHLEHLNLAHNRLAQGMALGAGGLGPLPHLTALDLSGNSLYSGLAEQLLGEAPALRTLSLAENSLTRLARHTFRGAPALEWLDLHSNVLMDIEDGAFEALPRLAHLNLSRNSLTCISDFRLQQLRVLDLSCNSIEAFQTAPEPPAEYQLAWLDLRENRLLHFPDVTALPRLVYLNVSNNLIRLPEGPPQGGEGIHAPSEGWAALPASNPGRNASTPPLSQLLNLDLSYNEIELVPEGFLEHLTSLRFLNLSRNCLQAFRAWGAGSLPCLMRLDISHNALEKLELGAGALGSLRTLLLQDNALWDLPPYAFASLASLQRLNLQGNRISPCGGPGEPGPSGCVAFSGISSLRFLNLVDNKVETLRAGAFLHTPLTELDLSANPGLDVATGALAGLEGSLEVLALQGNGLATLQVDLPCFSCLKRLNLAENRLSRLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLTCHFGSQEAVSLSHVRPEDCEKGGLKNVNLVIILTFALVAAVLLTTLATCCCVRRQKFSQQYKA
The following text describes a protein:
Function:
The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization. Plays a role in olfactory cilium biogenesis/maintenance and trafficking (By similarity).
Miscellaneous:
MISCELLANEOUS: [Isoform 3]: Based on a readthrough transcript which may produce a DPP3-BBS1 fusion protein.
Subcellular Localization:
Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Sequence:
MAAASSSDSDACGAESNEANSKWLDAHYDPMANIHTFSACLALADLHGDGEYKLVVGDLGPGGQQPRLKVLKGPLVMTESPLPALPAAAATFLMEQHEPRTPALALASGPCVYVYKNLRPYFKFSLPQLPPNPLEQDLWNQAKEDRIDPLTLKEMLESIRETAEEPLSIQSLRFLQLELSEMEAFVNQHKSNSIKRQTVITTMTTLKKNLADEDAVSCLVLGTENKELLVLDPEAFTILAKMSLPSVPVFLEVSGQFDVEFRLAAACRNGNIYILRRDSKHPKYCIELSAQPVGLIRVHKVLVVGSTQDSLHGFTHKGKKLWTVQMPAAILTMNLLEQHSRGLQAVMAGLANGEVRIYRDKALLNVIHTPDAVTSLCFGRYGREDNTLIMTTRGGGLIIKILKRTAVFVEGGSEVGPPPAQAMKLNVPRKTRLYVDQTLREREAGTAMHRAFQTDLYLLRLRAARAYLQALESSLSPLSTTAREPLKLHAVVQGLGPTFKLTLHLQNTSTTRPVLGLLVCFLYNEALYSLPRAFFKVPLLVPGLNYPLETFVESLSNKGISDIIKVLVLREGQSAPLLSAHVNMPGSEGLAAA
The following text describes a protein:
Function:
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. During mitosis, it mediates the ubiquitination and subsequent proteasomal degradation of AURKA, causing mitotic arrest. It also regulates mitochondrial function by mediating the ubiquitination and proteasomal degradation of the apoptosis inhibitor BIRC5.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MRPVPLRNRKSRKALFLPSLPPSLALAPGANQKPWGQREQGQEWSLLSEGRKGSAAAATEAGGQARQGKGSSSISSDVSSSTDHTPTKTQRNAATSEDSDLSMRTLSTPSPALICPPNSHSLQNGKSSSTSSSSVTGETIAMVHSPPPTRLTHPLIRSASQLQKEQANINRLPDQSVIQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLMGETINVDRALKVLTRRLCQDTPNVCLMLETVIVSGCRRLTDRGLYTIAQYCPELRQLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPMHGKQISICYLDMSDCFVLEDEGLHTIAAHCTQLTHLYLRRCIRITDEGLRYLMIYCTFIRELSVSDCRFVSDFGMREIAKLESRLRYLSIAHCARITDVGIRYITKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSNIGLEFLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCEISVEALRFVKRHCKRCIIEHTNPAFF
The following text describes a protein:
Function:
Required for chitin fiber assembly and organization involved in cuticle formation and tracheal development.
Miscellaneous:
MISCELLANEOUS: The name 'retroactive' likely refers to the propensity of hyperactive larvae to change orientation within the egg case.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MQFTSLLLAVIFLISLVSIDGLLRRCYQCRSRGELGSCKDPFTFNATDVEQEPGVAAIPCASGWCGKVIEGGGTYAIDDYDLAIQRMCVQRGPDDNMDRCADTIYNYKKVYMCFCQGDLCNGARSWSSAPQMILITMLPLLGSWLLQRMRN
The following text describes a protein:
Function:
Involved in cytokinin biosynthesis. Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP.
Sequence:
MIVSLSLCKQTMSLLDIPSGVLKSNFFRPRLEKEKVVILMGATGTGKSRLSIDLATRLPAEIINSDKIQVHAGLDIATNKIPEEERCRLPHHMLGVISPYTDFTATDFVDMASHAMDSILSRSQVPIIAGGSNSYIEALVDDEDFRFRSRYECCFLCVDVAMPVLHQYVSERVDKMVEMGMVDEVRSFFDANANYAVGIRKAIGVPEFDRYFRAEPYLDKQQRGKLLQEAIQEIKRNTCKLACRQLEKIHRLRNKKNWKIHMVDATEVFRRRGKDADEAWEKLVSGPSTEIVAEFLYNFSPQTLVTKPNLRVPSLPCGIML
The following text describes a protein:
Function:
Splicing factor that contacts pre-mRNA directly and is a component of the pre-mRNA-U1 snRNP complex (commitment complex 2) that forms during early spliceosome assembly in yeast extracts.
Miscellaneous:
MISCELLANEOUS: Present with 4170 molecules/cell in log phase SD medium.
Sequence:
MADEKRLEDLRSKIMESIGKSEKDVVPIENKRFNTDNAVIDTHFKRQKSDGELPKAPKSRNVSHSNNRGPSSIITMSTNRTTYEQTRAGPHRQSYRDASGRSYNRENRYSSHNTGPQWNNNPYNRQRDERRGRNERFDRRGRNGNGNYDRFNYQRKNEGSKFNGDRDKRQLQTNKYDMNYNSQNVMYPGSSFDSPAYYNMASSKANSRLVISGLSQSSDPSIVARLKDLLENFISGLQKTESNAEDFKISNFYIGEGRPDHIIVEFSSQICSTMVLACRSFFNAKLGTFDLKWRRPNDYVQQLDHLVDFCRGTVIALENLENIGEGEDYRMKELFSSLNVTNGTAKPLFYKCSSNTNNTGKESEFTKCILLSFEVVTQDILDKLKPYKWFKPNDGKISQVTSWITFQSLPNLVTQSVRVESRVLLLLNCLDPLDLKDETFITEIKETLKYSIAGADTIKICQPGVDYRLNFENLASGAGNIYIKFKTLEAAKHAMEELPGTQFNDRTVLCTYIDEDDFDMMEATQLS
The following text describes a protein:
Function:
Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSVYLLHLASTHAHFHLPELETLAKIENVEFWLIPKSEYLNVAFKSDKSRNQALFSHAIKEFQDSISPNDATTQNPFMLAVVNSNEDARRWIRRSIFCKGIYEIYCIGDSFTRLHEKMKELNPAPWDSFKHNSSYKFTFETFGTRRTMKEQLSIISDFEYMQLQGPVSMHNPQHVFTVLENRRNNVEGPKVYFGHWCGSGSRDAIDTFDLKQRSYIGITSFDAELSLVTAQMAMAAPGKLIYDPFVGTGSFLYTCSFFGAHTLGSDIDGRQMRGKNGRSIKSNFRQYKLSPFFLDTFTGDVTNCPLRKNLLLDAIVCDPPYGVRAGAKKIAKCSQRPPKESSSTGNHYPKLEQYQISDMVYDIICFASDRLVDGGRLVLWLPTITEEYGIDDIPSHPYLSLIYNSIQPFTHWSRRLLTFQRLPRAHDSKSLNLLPKINNKTPSHHNFREKYFSSAGRASASTKFSPVLE
The following text describes a protein:
Function:
Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MVRPSSSSSASASAARSGAAKRKRNLPTATNPTTRASVAANVKGKGKTKALELDLVVSDDGEEDGELDLESDSGDDDANDDDDNDNEQDDFPEIDLEDSDDDQDVEDEDEPGAQEEVDSDNNKQASTQVHDIQVEEDDSSEEGYNSSDIDNSDFDDDADEGDLAYDSADEDERASAFAARSDASQTSIDEELSRMMSRYSSKPDEHSGSLSATNKLGIPRSQAAQAFDLRVRNPDGSAKGVFKRSEITGEMKRVYPEIDAAYDSDSSTEDPENRIGNVPLEWYDDLPHIGYDINGRKVMKPATKDELDKFLDTVDGDGEAWFSARDKSTGKDVRLSDEELAIIRKLQNAEIPDDAYDPYEDYVDWFTGEDKVMQTALSGRPEPKSRFVPSKWEHKKVMKIVRAIREGRIVPGAAANKDAKPKFYNIWADAHENDTRSPWAVMAAPKLALPGHAESYNPPAEYLFNEQEQKEWQEAEAEDRKQNFLPTKHDSLRRVGAYQNFVQERFERCLDLYLAPRMMRKKLDIHNPENLLPKLPSPKELRPFPITTSVVYVHPDGGRVRCLSVDPTGNWLVTGGDDGRARLWDVAIGRCTASWDVCEGMPKAERSAVHSIAWCPTKNYSLFTAVVHGRVAVIAPPQTQNYAKTSANAISSKSASSSSGATATSTASFLYATSAAATSMPSKPDARSPVAWTRPSEAERRTGVAMHLNITSPSAANLKTVVWHNKGDYFATVCPDSAAGSAGLLIHQLSKHRSQSPFRKASKGSSIQKLVFHPTKPWIFVATQRYIRIYDLMAQSLIKTLQSGFKWISTLDVHPSGDHLMVGSYDKKLAWFDLDLSARPYKVLKYHARAIRSVHFSTSWNLVADASDDGTLQLFYAKVGADYGENLTLVPLKVLRGHEVKNGLGVLDVKWHPNQPWLFSAGADGNALLWTT
The following text describes a protein:
Function:
Functions as a two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Domain:
Histidine-containing phosphotransfer domain (HPt) contains an active histidine that mediates the phosphotransfer.
Sequence:
MAANRQALNEQLQKIVDSLKEQGMLDKQFGLVHSLKESNSPFFLAEIIPMFCQNVQTILRDLTQTLDKEPVNYYDLEEYCIKLKGCTSSIGARRMALACVTLRQASENKNKDGCILALNGIKHEYYNLQSSLDSIVQLERRILCHNA
The following text describes a protein:
Function:
Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
Sequence:
MKNILLGVTGGIAAFKSASIVSLLKKKGYNVKVVMTKNATNIIGPLTLETLSRNRIYVDMWDTNPHYEVEHISLADWADMVLIAPATYNIIGKVANGIADDMLTTILSAISVRKPVFFALAMNVNMYENPILKENVDKLKSYGYRFIEAEEGLLACNYVAKGRMSEPKDIVEEIERYNIYSKIENCDTTLKGKKLLITSGRTKENIDPIRYLSNNSSGKMGYCLVQAAVDLGAEVTLISGPTNLDIPKGLKNFISVESAIQMYEKVDEYFKDTDIFIACAAVADYRPKEYKKEKIKKSDSDLTIELVRNPDILAEMGKKKDKQLLVGFAAETNDIKKNALKKLEKKNLDIIVANNASTMGTDSNTIEVIKRDKSSVEIKQKNKIELAYDILLEVILELKKDKNE
The following text describes a protein:
Function:
Binds to the promoters of genes with functions important for the G1/S (start) transition; primarily genes involved in pheromone response, polarized growth and transcription.
Miscellaneous:
MISCELLANEOUS: Present with 284 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSSQFPSSPYRTVDPYSPPNYKQQPNCPSSNYEKAGKTASESIGNFGKGDYPTPFPSSSIGRVSSPVRSNKVDAIPSSPAFPGQLAETSPKFSSKLSSPSRHTRVINAELDPSKISTITVGRNSSQCDVALCKNKFISRVHASITYLPQTNEVKIHCFSMNGLIVTYRKQFDCYQLKDTMNNNNRAYRLVPRFSNEKCVKEIQDEGGFINFTLEEGDTVYMTYYKGIMLDFRQVLLRISLKEKNSSSEPLRFEKKAEFESESETKHMGSIRKHPLIFTDTSMDRPKKILKDSNKISIGSDSGVAERMLNHFLNSKSSPLSSVSSVDHEEQTLRQDSLSSDKNPMTMKKPKLNKRVLPSKPKKSVKENLDELSRRNIDVMHLQHILTNHLAFANVQQTPLFQLQQVNSQISELSRDELRSILSDAKCVGVIYRHGKDAAGKPLDEEYFYDLENDDDYERRNLVSSLKGGRTGLRSCRRTHKQYFWKKPAK
The following text describes a protein:
Function:
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Involved in the morphogenesis of epidermal tissues.
Subcellular Localization:
Cytoplasm.
Sequence:
MVNFTVDEIRALMDRKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGSKAGETRFTDTRKDEQERCITIKSTAISLFFELEKKDLEFVKGENQFETVEVDGKKEKYNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLFMNKMDRALLELQLGAEELFQTFQRIVENINVIIATYGDDDGPMGPIMVDPSIGNVGFGSGLHGWAFTLKQFAEMYAGKFGVQVDKLMKNLWGDRFFDLKTKKWSSTQTDESKRGFCQFVLDPIFMVFDAVMNIKKDKTAALVEKLGIKLANDEKDLEGKPLMKVFMRKWLPAGDTMLQMIAFHLPSPVTAQKYRMEMLYEGPHDDEAAVAIKTCDPNGPLMMYISKMVPTSDKGRFYAFGRVFSGKVATGMKARIQGPNYVPGKKEDLYEKTIQRTILMMGRFIEPIEDIPSGNIAGLVGVDQYLVKGGTITTYKDAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIFEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVQSESNQICLSKSPNKHNRLHCTAQPMPDGLADDIEGGTVNARDEFKARAKILAEKYEYDVTEARKIWCFGPDGTGPNLLMDVTKGVQYLNEIKDSVVAGFQWATREGVLSDENMRGVRFNVHDVTLHADAIHRGGGQIIPTARRVFYASVLTAEPRLLEPVYLVEIQCPEAAVGGIYGVLNRRRGHVFEESQVTGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPLEAGTKPNQIVLDTRKRKGLKEGVPALDNYLDKM
The following text describes a protein:
Function:
Catalyzes the ATP- and NADPH-dependent reduction of carboxylic acids to the corresponding aldehydes (By similarity). In vitro, also catalyzes the activation of medium/long-chain fatty acids as acyl-adenylates (acyl-AMP).
Domain:
The N-terminal domain likely catalyzes substrate activation by formation of an initial acyl-AMP intermediate, the central region contains the phosphopantetheine attachment site, and the C-terminal domain catalyzes the reduction by NADPH of the intermediate thioester formed from the attack of the phosphopantetheine thiol at the carbonyl carbon of acyl-AMP.
Sequence:
MSINDQRLTRRVEDLYASDAQFAAASPNEAITQAIDQPGVALPQLIRMVMEGYADRPALGQRALRFVTDPDSGRTMVELLPRFETITYRELWARAGTLATALSAEPAIRPGDRVCVLGFNSVDYTTIDIALIRLGAVSVPLQTSAPVTGLRPIVTETEPTMIATSIDNLGDAVEVLAGHAPARLVVFDYHGKVDTHREAVEAARARLAGSVTIDTLAELIERGRALPATPIADSADDALALLIYTSGSTGAPKGAMYRESQVMSFWRKSSGWFEPSGYPSITLNFMPMSHVGGRQVLYGTLSNGGTAYFVAKSDLSTLFEDLALVRPTELCFVPRIWDMVFAEFHSEVDRRLVDGADRAALEAQVKAELRENVLGGRFVMALTGSAPISAEMTAWVESLLADVHLVEGYGSTEAGMVLNDGMVRRPAVIDYKLVDVPELGYFGTDQPYPRGELLVKTQTMFPGYYQRPDVTAEVFDPDGFYRTGDIMAKVGPDQFVYLDRRNNVLKLSQGEFIAVSKLEAVFGDSPLVRQIFIYGNSARAYPLAVVVPSGDALSRHGIENLKPVISESLQEVARAAGLQSYEIPRDFIIETTPFTLENGLLTGIRKLARPQLKKFYGERLERLYTELADSQSNELRELRQSGPDAPVLPTLCRAAAALLGSTAADVRPDAHFADLGGDSLSALSLANLLHEIFGVDVPVGVIVSPASDLRALADHIEAARTGVRRPSFASIHGRSATEVHASDLTLDKFIDAATLAAAPNLPAPSAQVRTVLLTGATGFLGRYLALEWLDRMDLVNGKLICLVRARSDEEAQARLDATFDSGDPYLVRHYRELGAGRLEVLAGDKGEADLGLDRVTWQRLADTVDLIVDPAALVNHVLPYSQLFGPNAAGTAELLRLALTGKRKPYIYTSTIAVGEQIPPEAFTEDADIRAISPTRRIDDSYANGYANSKWAGEVLLREAHEQCGLPVTVFRCDMILADTSYTGQLNLPDMFTRLMLSLAATGIAPGSFYELDAHGNRQRAHYDGLPVEFVAEAICTLGTHSPDRFVTYHVMNPYDDGIGLDEFVDWLNSPTSGSGCTIQRIADYGEWLQRFETSLRALPDRQRHASLLPLLHNYREPAKPICGSIAPTDQFRAAVQEAKIGPDKDIPHLTAAIIAKYISNLRLLGLL