lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Flavin-dependent oxidation of thiol-containing compounds. Probably required for the correct folding of disulfide-bonded proteins (By similarity).
Sequence:
MCLPTIRKIAIIGAGPSGLVTAKALLAEKAFDQVTLFERRGSPGGVWNYTSTLSNKLPVPSTNPILTTEPIVGPAALPVYPSPLYRDLQTNTPIELMGYCDQSFKPQTLQFPHRHTIQEYQRIYAQPLLPFIKLATDVLDIEKKDGSWVVTYKGTKAGSPISKDIFDAVSICNGHYEVPYIPNIKGLDEYAKAVPGSVLHSSLFREPELFVGESVLVVGGASSANDLVRHLTPVAKHPIYQSLLGGGDIQNESLQQVPEITKFDPTTREIYLKGGKVLSNIDRVIYCTGYLYSVPFPSLAKLKSPETKLIDDGSHVHNVYQHIFYIPDPTLAFVGLALHVVPFPTSQAQAAFLARVWSGRLKLPSKEEQLKWQDELMFSLSGANNMYHSLDYPKDATYINKLHDWCKQATPVLEEEFPSPYWGEKERSIRENMWSIRAKFFGIEPPK
The following text describes a protein:
Function:
Serine protease inhibitor. Inhibits trypsin (Ki = 110 nM) and very weakly inhibits chymotrypsin (Ki =1200 nM). Does not inhibit bacterial subtilisin.
Sequence:
GQQPLCNDCFACARSLCICGDLVPQCHEGCQQCEKVDTLSGKPLYQCRSFEDYQCAN
The following text describes a protein:
Function:
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Subcellular Localization:
Secreted.
Sequence:
MGRMRISMFLATILHLLVSVVPYTIEVTDDGDEHEVYVGAVLSPLKHVTSVCGMKADSGPCKALNDRYHFNIKTHQCEIFNYGGCQGNENNFLTLEECQEKCITPFEDLPEKRKRSRFKKEKPSYCLLENDPGICRGLITRYFYNKESQKCEKFMYGGCLGNQNNFWSVEECQETCQDTSFVEEKDRLVNSLQINDDSILFTTTDNSTLVDQYVLPVNSLQTEDGVLPFDAVENSTPTLQQGITNMLLIRQTFVIFLIFSESVVPSTVESRLSNVNGPAEHWISEYVG
The following text describes a protein:
Function:
Involved in the biosynthesis of the enzyme cofactor mycofactocin (MFT). Catalyzes the oxidative deamination of AHDP (3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one), forming an alpha-keto amide moiety on the resulting molecule, which is called pre-mycofactocin (PMFT). This reaction occurs via a 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one intermediate, which converts to PMFT. The alpha-keto amide moiety is the redox-active center for the redox activity of mycofactocin.
Sequence:
MADEWFETVAIAQQRAKRRLPKSVYSSLISASEKGITVADNVAAFSELGFAPHVIGAAEKRDMSTTVMGQDISMPVLISPTGVQAVHPDGEVAVARAAAARGTAMGLSSFASKTIEDVIAANPKIFFQIYWLGGRDAIAERVERARQAGAVGLIVTTDWTFSHGRDWGSPKIPEQMNLRTILRLSPEAIVRPRWLWKFGKTLRPPDLRVPNQGRRGEPGPAFFAAYGEWMGTPPPTWDDIAWLRELWGGPFMLKGVMRVDDAKRAVDAGVSAISVSNHGGNNLDGTPASIRALPAVAAAVGDQVEVLLDGGIRRGSDVVKAVALGARAVLVGRAYLWGLAANGQAGVENVLDILRGGIDSALMGLGHSSIHDLRSDDILIPADFVRRLGR
The following text describes a protein:
Function:
Hydrolase with a preference for pyrimidine substrates. Has high activity with 5-methyl-dCTP, and much lower activity with CTP, dCTP, 5-hydroxy-dCTP, 2-hydroxy-dATP and 8-hydroxy-dGTP.
Sequence:
MKMIEVVAAIIERDGKILLAQRPAQSDQAGLWEFAGGKVEPDESQRQALVRELREELGIEATVGEYVASHQREVSGRIIHLHAWHVPDFHGTLQAHEHQALVWCSPEEALQYPLAPADIPLLEAFMALRAARPAD
The following text describes a protein:
Function:
Radical SAM enzyme involved in the synthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNAs. Catalyzes the cleavage of the C(epsilon)-N bond of the lysine moiety of q0kN15-tRNA, leading to the formation of archaeosine at position 15 in tRNAs.
Sequence:
MTYWTSEDNVAGKPGTALFIILPTIGCYRYRIGQACYMCSYPTAAPKVKWTQEAIVNYVKEALEKIEGTEGPFAVRMFTSGSFLDNGELKPETRRKIFEILAEMDNVEEIVIESRSELVRYEAVKELAEIVPDKHFEVAIGLETANDDVADVSINKGNTFADFVKAAEITHKAGAKVKTYLLLKPIFLSERDGVEDAKESIIKAEPYTDTFSINITDIQKGTLYERLWEKKEYRPPWLWSAVEVLIWAKRKFPNKRILSDPVGAGSKRGPHNCLTDYDRVIGKAIKKFSATQDLSYIENLKPECRDRWEYIVENGLLDWQLVTW
The following text describes a protein:
Function:
Positive brassinosteroid-signaling protein.
Subcellular Localization:
Nucleus.
Sequence:
MRTGKGNQEEEDYGEEDFNSKREGPSSNTTVHSNRDSKENDKASAIRSKHSVTEQRRRSKINERFQILRELIPNSEQKRDTASFLLEVIDYVQYLQEKVQKYEGSYPGWSQEPTKLTPWRNNHWRVQSLGNHPVAINNGSGPGIPFPGKFEDNTVTSTPAIIAEPQIPIESDKARAITGISIESQPELDDKGLPPLQPILPMVQGEQANECPATSDGLGQSNDLVIEGGTISISSAYSHELLSSLTQALQNAGIDLSQAKLSVQIDLGKRANQGLTHEEPSSKNPLSYDTQGRDSSVEEESEHSHKRMKTL
The following text describes a protein:
Function:
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular Localization:
Cellular thylakoid membrane; Single-pass membrane protein. Membrane; Single-pass membrane protein. Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
The following text describes a protein:
Function:
DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides back-up AP endonuclease (APE) activity to apn2 together with uve1.
Subcellular Localization:
Nucleus.
Sequence:
MCAINKAYLLTKFYISANSCAFFVKSQRKWTSPDLSEDVAQKFLETASEMKFDASKQVLVHGSYLINMANADEQKREQAFNCFVDDLKRCERLGVGLYNFHPGSTASCTKEEGINNLAECINRAHEETKSVIIVTENMAGQGNCLGGTFDDFAALKSKIKNLDRWRVCLDTCHTFAAGYDIRTEESYKKVIDEFDEKVGAKYVSGWHLNDSKAPLGSNRDLHENIGLGFLGLEPFRLIMNDSRWDGIPLVLETPAKSPEQWKKEVELLRFMVGKSSDDVELMKESARLSNLGAASRKEHLNKFEKKEAKKDRKKKSKDGDQTTLLLRKKQKLGNAEVKSLDE
The following text describes a protein:
Function:
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.
Sequence:
MSFQKVDPAQIESVLSKLTLEEKISLLAGKNFWETQDYPEKGVPPVKTSDGPNGARGATFKGGVTAACFPASSLLAATWDLDAAKHIGEALADETRSKGARVLLAPTVCIHRHPLGGRNFESFSEDPFLAGKLAAQYIKGLQGNGVAATIKHYAANEQETCRFTVNEHITERALREIYLKPFEIAIKESNPLAVMTAYNIVNGTHADSNNFLLRDVLRGEWGWKGLVMSDWGGTNSTADALNAGLDLEMPGPTRWRKVDEVLAVVKSGAVLEETIDERARNVLELLAKLNCFENPTIPEEKAINRPEHQKLIRSVGSQGLVLLKNEGDVLPLRKEILTNKKVALLGFAREALIHGGGSASVNAHYRVTPEEGLRAALGDTVEFEYAKGAHTFRQLPLMSDNVVNLEGQPGWTLDFFADEEPNGEPGSSISSEQPSYIPLFVKESWGSVRASAHFTPTQSGKHYFGMSGLGRSKLLIDGEVIYEQKLNCPDSMGFLLGGVEEPEIQYSFEAGKTYAVEVVSVKPTSKGGLALLDGFIGFRLGFMTEEEHNRDLLSEAVDVAKRSDIAIVFTGHTPDWETEGQDQISFHLPSNGSQDRLVAAVGAANPNTVVVNCTGVAVAMPWLDKVKAVVQAWFPGQEAGNAIADVLTGAVNPSGRLPVSFPRAIEDAPAHGNFPGDYTDGKDNRRHLEVTYKEGVFVGYRHYDLSEANRAKVLFPFGYGLSYTTFTHANHKASATSRNTVEVAVDVTNVGTCAGADVVQVYAGAKLAVPENPVKELVGFAKVHLKPGETKTANITFEVRQLTHFTERSGKWELESGDYEISIGQSVRDITGKVEIGLEAQNYKP
The following text describes a protein:
Function:
This promotes the activity of RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MSCIDSVGLDDQELAGHLDVMLCSSSDDDKRKSSSLDQSSSTCSHPLVMKLVCTTCGQKMSNFYGLPFDYIMGGLRLSETKADWTRDAETDFVLSKKKLFLVLDLDQTLLHSTVDLTPEENYLKNQMDSLQDIFKLITREGFSPSYAKLRPFVRNFLQEASTMFKMYVYTNANKSYARKMVNLLDPDNIYFKSRLITREDSTVSCQKNLDVVMGQERAVVILDDRTDVWPMHKDNLIQVQRYKYFASTANWSNSKSFAQREVDESTDIMATYLEILKKIHSQFFDPKLDEDNLASRDVRDVMRTVQAGILQGCKLILRKNLTAKYKLDNLSKMAEKLGAICVSELDPTVTHVVTLEAKPEDDQLQLENKKKKKNKQKGTYHLVFPEWIRDSYKLWHRMPVENYLP
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
QLRSGFNMDDWDSENFEPADVKLNSDKWEGEDEEDVLKDNWDDEEEEKEKEEEKPKVEVKKGGKKYLQMKLKEKEEEKKREAERRRQEEEEKTPEEKMRDKLLAQKLAEESDMAMTKELFTKEETTETSVSFGDYNPRTKADFIEFAELIKTKLTSLEESPHYAFLVETLVNSCTVCLNHEEIKKISSSLNALASEKLKQERAKKGTKKTQKAKLGGGMKSTRNDAMEDFSSYNDFDDFM
The following text describes a protein:
Function:
The main replicative DNA helicase, it participates in initiation and elongation during chromosome replication. Travels ahead of the DNA replisome, separating dsDNA into templates for DNA synthesis. A processive ATP-dependent 5'-3' DNA helicase it has DNA-dependent ATPase activity.
Sequence:
MSAVDLRKVPPQSIEAEMSILGGVLLDNEAINRCLELIEADDFYRESHRKIFRAMIDLSNRSEPCDLITLTDMLKRKGELEEVGGGAYLATLVDYVPTAANIAYYCRIVKEKSVTRRLITAATDIVTRGYDEETTVDELLDGAQKTIFEISENKLRPAFTPVGTILKDTFKRIETLYEKKEHVTGVPTGFYDLDKMTAGFQPGDLIIIAGRPSMGKTAFSLNIAQYAAAHADPPLPVAVFSLEMSKESLVMRLLCSESRVDASRLRTGHLVDTDWHKLTHGADKLSKARLYIDDTPAIPVLEMRAKARRLKAENGLGMIVVDYLQLMRGSSQESRQQEISEISRSLKALAKELDVPVVALSQLNRSLESRTDKRPMMSDLRESGAIEQDADVIMFVYRDAVYCDDCKKRDGSCTKGHEKDAEIIIGKQRNGPIGSVNLLFNGEFTKFENMEKHHDY
The following text describes a protein:
Function:
Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors. Involved in the regulation of T-cell poliferation and activation. Affects TCR clustering upon receptor triggering and modulates its internalisation, playing a role in TCR-dependent T-cell activation.
Subcellular Localization:
Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Associated with forming but not mature clathrin-coated vesicles. The recruitment to coated-pits precede the one of clathrin and the adaptor protein complex AP-2. According to PubMed:17617719 it may also dynamically associate with Golgi/TGN membranes.
Sequence:
MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC
The following text describes a protein:
Function:
3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.
Subcellular Localization:
Cytoplasm. Cytoplasm, P-body.
Sequence:
MTYNAVPPPSGLYSAPQPSKSSSTGKRVSGGGAGGHSQARRDGGVQGSSSMQRDDENEEGVSGGRRKFESPGPSRDTEVASQDHAQGTRKPFPSVRSPTPTKLPLPSPGLLPTPRISGRQTGGIRQPDFAQHSSSARKKYPRNEVAPQGLQRPLQASNSYVALGSSPVFRQSGSHARASPAALSYSAAQEGSARGGVVHQHDVTQSPFYGGERQTRSAYQQRQGLHETESSFGSSVQRGNAAAGLGHAAEQSQTGGSRSPLLATPARKIIFSDNQGADSTERALLMTPSLGDGLLFSPPRDRGLLASAPPSQRIEPSAPPLLQRPVDLFEEIERSFGMQTRLFDTAFGPNSQPQTPNVKTPAFKAQTLKTPAAKRPPLHAAPSPALLPTPGKLAFLTPAKQVQDAAAAAWAMVSGTPGILSSPAHFGTNQKAPAVNSSPARAPYPEHWRPEEISQGVKRGELFKAVLRVNAFRRMEAYVTIEGIGTDVLIDGLIAQNRAIEGDTVYIKVDPPSKWPLLKGAKPDETPSEASSVSGLSSVLEKLNLGTTRGGMFGLEDSGEDESDRGSLGVGSLGTESSFAESLGSRIAGNFAGRTKGDYTNGHGGVNGSEGPDEVQKELDDLLRQLRGAGGEHGRGGGSVGSMETEDGSAVGSLEGRSARARLAVAESEEGGDRDTCNDTESLSEGDLYSSRGSEAGTEEERRQSPSEKAVEKLAAELKGAPNRRPTGFVVGIAEFSSRREALVGYLQIPTKPSKPCTPAKPSPDTPVKGLFQDSGNDSPTFTAFTSPSITLMPADPRMPKMTVWVDGLPDGLKERVREGDPTVNTTLVAARLDCWKAQHYQPLAVVRQSLGQAGEIETETAAIMFMYKIHGPDFPPEALECLPPTPWGIPPDELARRRDLRGERIFTIDPPTARDLDDAVSVKRLGNGNIEIGVHIADVSFFVRPGTELDKEARRRSTSVYLIQRVLPMLPPLLCEQLCSLNPGVDRLAFSVIWELTPGGEIVRQWMGRTVIASCCKLAYGHAQAMIEDRFDPENFVPGPQTGPKPPALHGNHAWADVIADVIALNDLARSLRRARFESGALRLDNTKVVFKLDADGNPDGVAVYESLEANRLIEEFMLLANRSVAGAISRAFPEAALLRRHPPPNERKLEELAKLCEAHGFDINLSSAGALHASLEEIRAATAHDAAIADVIRLSATKPMNLAKYFCTGELLGAPEDWGHYALATPLYTHFTSPIRRYPDLVVHRTLAAALEAESNLCELQGVSSGLASLDGGDSQPFTGPVTGDVKEALLTWHGALWDDEKGDRGVEKRAVAVAGKAHGVPEKAELQGVATYCNERKLASKQAQEASDKVFLCVLLKRRGGMVSDARVVSLGPKWATVYVTRFGLERRIYFEDLQGAQAEFFESTRTVVIGEARESGRSAKKVARKAAVVEEYGDALAEDAAAVGVEAAVLPMTLRMLSSVPVVCYAITGNNRPMDIGVRLYL
The following text describes a protein:
Function:
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
Subcellular Localization:
Nucleus.
Sequence:
MDATTLTGHVKELNAANQAGKSDEVISLLKKLQAEVVPTEDLLRSSKAGVAVGKLRTHATPSVSSLAKEIVKKWRDAVEETKKKRKRAEGDEGKDVKKEKEEGNGKRVKAETGSLAATPSASTPASASTPDVKATSPPVRQPLSTIDSSRTTPRTAKSDGVADSLRADSSEGGSVDSVRDKCVIMIYDALALDSTAEIKILKERAIGIERAANKAMNFSTGNDYRAKMRSLFLNLKDKGNPALRNEIVLGYVSTEKVASMSKDEMASESVRMLKEKIASDNLFKAKAVGVTQAETDAFKCGRCHQRKCTYYQMQTRSADEPMTTFVTYVSDLTPKESLLTTCTTCSFYSDVLIVTTGGNSASFGFCLWGALYLSGFLSRRLCSQYIYEAYRCDLRVNVTKPLSAVNMPFCSVLKFK
The following text describes a protein:
Function:
In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
Sequence:
MSLAGILTDAEIAAGLESCKAPDSFNSKTFFAKSGMHGKSKDQLTKVFGILDQDKSGYIEEDELQKFLQNFAASARLLTEKETKVLLSAGDTDGDGKIGVDGKVTPIKAISSISDDQPMSADPCAAKHDHPFRKPSVDLQHFDIQKYKQAACKIRVAKCKDIGILRLLHLLSDVLLSIPKAL
The following text describes a protein:
Function:
Component of the linker nucleocytoskeleton and cytoskeleton (LINC) complex that regulates telomere movement and meiotic recombination during meiosis. Connects the spindle pole body with the nuclear envelope through its interaction with MPS2 and mediates meiotic bouquet formation and rapid chromosome movements in meiotic prophase. Functions as an integral membrane anchor for telomeres and is a nuclear receptor for the SIR4 pathway of telomere tethering and gene inactivation. Essential for nuclear division and fusion and required for the first step of spindle pole body duplication in G1. Functions in sister chromatid cohesion establishment. Recruits double-strand breaks (DSBs) to the nuclear periphery for chromosome healing.
Subcellular Localization:
Nucleus inner membrane; Single-pass type II membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Chromosome, telomere. Note=Localizes to the spindle pole body half bridge throughout the cell cycle. Relocalizes from the spindle pole body to the nuclear envelope in meiosis, via the interaction with HTZ1. The cohesin component REC8 promotes localization on nuclear envelope in mitotic cells.
Domain:
The SUN domain is involved in the binding to MPS2 and is important for modulating chromosome motion events that act in meiotic chromosome juxtaposition and by extension, promoting proper morphogenesis of the synaptonemal complex.
Sequence:
MNNSNEHRREEAGAANEQMPYNKAVKSAYADVLKDKMNREQEISLRAIKKGIYTDGGETDNYDMDKENDSAYEMFKKNLDFPLDQHNDDDDDDPYIEDNGQETDGYSDEDYTDEADKSFIEDSDSDSYDLESNSDFEENLESSGEAKKLKWRTYIFYGGLFFVFYFFGSFLMTTVKNNDLESHSSGATSSPGKSFSNLQKQVNHLYSELSKRDEKHSSELDKTVKIIVSQFEKNIKRLLPSNLVNFENDINSLTKQVETISTSMSELQRRNHKFTVENVTQWQDQLVKQLDTHLPQEIPVVINNSSSLLIIPELHNYLSALISDVIESPGIGTAGSAESRWEYDLNRYVKEILSNELQYIDKDYFIQEMNRRLQSNKQEIWEEITNRLETQQQQQQQQVQQDYSNVPQQYSSILMKRLIHQIYNSNQHQWEDDLDFATYVQGTKLLNHLTSPTWRQGSGVQPIELLTDSKQSSSTYWQCENEPGCSWAIRFKTPLYLTKISYMHGRFTNNLHIMNSAPRLISLYVKLSQTKEIKALQTLANQYGFGQHHKRDRNYIKIAKFEYRLTDSRIRQQMYLPPWFIQLKPLVRSIVFQVDENYGNKKFISLRKFIINGVTPQDLQIIENNEFPVLLGDTPEYGVTQNTDEGKRKVLLSKPPYASSSTSTKFHPASNVPSFGQDELDQ
The following text describes a protein:
Function:
Involved in galactitol catabolism. Catalyzes the oxidation of galactitol to D-tagatose. Can also catalyze the oxidation of D-sorbitol to D-fructose.
Sequence:
MRLNNKVALITGAARGIGLGFAQAFAAEGAKVIIADIDIARATTSAAAIGPAAKAVKLDVTDLAQIDAVVKAVDEEFGGIDILVNNAAIFDMAPINGITEESYERVFDINLKGPMFMMKAVSNVMIARARGGKIINMASQAGRRGEALVTLYCASKAAIISATQSAALALVKHGINVNAIAPGVVDGEHWEVVDAHFAKWEGLKPGEKKAAVAKSVPIGRFATPDDIKGLAVFLASADSDYILAQTYNVDGGNWMS
The following text describes a protein:
Function:
Cis-prenyl transferase involved in the synthesis of dolichol, a long-chain polyprenol that is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Catalyzes the sequential condensation of isopentenyl pyrophosphate (IPP) with farnesyl pyrophosphate (FPP) to produce a polyprenyl pyrophosphate which contains 11 (major) and 12 (minor) isoprene units.
Miscellaneous:
MISCELLANEOUS: The synthetic pathway for dolichol synthesis is conserved in Giardia lamblia, even if some of the important enzymes are different from those of higher eukaryotes or remain unidentified.
Sequence:
MIPMHVAVIMDGNGRWARKQLQERTFGHEQGVSVLESIVDECINCGIRFLTVYAFSTENWSRPPTEVSFLFELLSAAIQRVRTTYRERNVKVQFCGERTTQIPETVIAAMNCIEQDTAACTGLILSVCFNYGGHTEIAQACRSVLADCLEGDAVENIKTRLQMPIEQFIQQIDTHLYANLPPVDLLIRTGCEKRLSNFLPWHLAYAEIIFSDLLWPEFSVRAFKDCLDEFASRTRRFGGVQLSPMTGVYSDTHPHSSTNALSNHD
The following text describes a protein:
Function:
Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.
Subcellular Localization:
Secreted.
Sequence:
MCPRPREVPGHTTVPPSPPPAPLASPHAHTPEAAPSGADYPAAAATAAAALQNSAAASVLRTSASFPRAMLPAATASLLGPLLTAWALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTADEGTGGRGFLLWYSGRATSGTGPPPGARRKWVTDPRVEWAAWGYWDEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPRDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPSPKPGTEPKVKPPRKSQPLEKTEETPSAPDAPAVTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSLIGAYKTGGLDLPSPPTGTSLKFYVPCKQCPPLKKGVNYLLMGQVEENRGPVLPPESFVVLHRPNQDQILTNLSKRKCPSQPVRAAESQD
The following text describes a protein:
Function:
Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation (By similarity). Involved in specification of the lateral neural plate border (NPB). May be required for segmental gene expression during hindbrain development (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MNCSPPGSCTDTERQRSGTPATPCATLAPTHPLRQANRLPIRRIKMLTAHTGHLLHPEYLQPLSSTPISPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVTSSEKESGRSSSLKLGESPLEDKSSFKPYAKGGETRKESGSSAGGAADKAGFRVPSGSCQPFPHAPSPSSRVSSPGQHCESKNNESQEKKEPEVNKSSLETSQANPTLTRASISNSSAESSQSGDVAPSSKSDPPSLGSGHVAPISPYKPGHSVFPLPPSGIGYHGSIVGAYAGYPSQYVPGLDHTKSSLVGNQLPGTLGLPGKPPSSSPLTGASPPSFMQGLCRDPYCLSYHNASHLGSSSCSTCVHDPSALKSGYPLVYPSHPLHSVHTTLSSSVTPSLSGHPLYTYGFMLQNDPVPHICNWVSASGPCDKRFATSEELLAHLRTHTALPGADKLLAGYPTGLGSAASCHLHLPPTGPGSPNTLPGSLSLRSPHTFGLSRYHPYGKGHLTAPNGLPVPSLPAGSYYSPYALYGQRLTSASALGYQ
The following text describes a protein:
Function:
Catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the primary cell wall formation, especially in roots.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MESEGETAGKPMKNIVPQTCQICSDNVGKTVDGDRFVACDICSFPVCRPCYEYERKDGNQSCPQCKTRYKRLKGSPAIPGDKDEDGLADEGTVEFNYPQKEKISERMLGWHLTRGKGEEMGEPQYDKEVSHNHLPRLTSRQDTSGEFSAASPERLSVSSTIAGGKRLPYSSDVNQSPNRRIVDPVGLGNVAWKERVDGWKMKQEKNTGPVSTQAASERGGVDIDASTDILADEALLNDEARQPLSRKVSIPSSRINPYRMVIMLRLVILCLFLHYRITNPVPNAFALWLVSVICEIWFALSWILDQFPKWFPVNRETYLDRLALRYDREGEPSQLAAVDIFVSTVDPLKEPPLVTANTVLSILAVDYPVDKVSCYVSDDGAAMLSFESLAETSEFARKWVPFCKKYSIEPRAPEWYFAAKIDYLKDKVQTSFVKDRRAMKREYEEFKIRINALVSKALKCPEEGWVMQDGTPWPGNNTRDHPGMIQVFLGQNGGLDAEGNELPRLVYVSREKRPGFQHHKKAGAMNALVRVSAVLTNGPFILNLDCDHYINNSKALREAMCFLMDPNLGKQVCYVQFPQRFDGIDKNDRYANRNTVFFDINLRGLDGIQGPVYVGTGCVFNRTALYGYEPPIKVKHKKPSLLSKLCGGSRKKNSKAKKESDKKKSGRHTDSTVPVFNLDDIEEGVEGAGFDDEKALLMSQMSLEKRFGQSAVFVASTLMENGGVPPSATPENLLKEAIHVISCGYEDKSDWGMEIGWIYGSVTEDILTGFKMHARGWRSIYCMPKLPAFKGSAPINLSDRLNQVLRWALGSVEILFSRHCPIWYGYNGRLKFLERFAYVNTTIYPITSIPLLMYCTLPAVCLFTNQFIIPQISNIASIWFLSLFLSIFATGILEMRWSGVGIDEWWRNEQFWVIGGVSAHLFAVFQGILKVLAGIDTNFTVTSKASDEDGDFAELYLFKWTTLLIPPTTLLIVNLVGVVAGVSYAINSGYQSWGPLFGKLFFAFWVIVHLYPFLKGLMGRQNRTPTIVVVWSVLLASIFSLLWVRIDPFTSRVTGPDILECGINC
The following text describes a protein:
Function:
Has non-porin-like, channel-forming properties and probably functions as an alginate permeability pore.
Subcellular Localization:
Cell outer membrane; Peripheral membrane protein.
Sequence:
MNSSRSVNPRPSFAPRALSLAIALLLGAPAFAANSGEAPKNFGLDVKITGESENDRDLGTAPGGTLNDIGIDLRPWAFGQWGDWSAYFMGQAVAATDTIETDTLQSDTDDGNNSRNDGREPDKSYLAAREFWVDYAGLTAYPGEHLRFGRQRLREDSGQWQDTNIEALNWSFETTLLNAHAGVAQRFSEYRTDLDELAPEDKDRTHVFGDISTQWAPHHRIGVRIHHADDSGHLRRPGEEVDNLDKTYTGQLTWLGIEATGDAYNYRSSMPLNYWASATWLTGDRDNLTTTTVDDRRIATGKQSGDVNAFGVDLGLRWNIDEQWKAGVGYARGSGGGKDGEEQFQQTGLESNRSNFTGTRSRVHRFGEAFRGELSNLQAATLFGSWQLREDYDASLVYHKFWRVDDDSDIGTSGINAALQPGEKDIGQELDLVVTKYFKQGLLPASMSQYVDEPSALIRFRGGLFKPGDAYGPGTDSTMHRAFVDFIWRF
The following text describes a protein:
Function:
Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling.
Subcellular Localization:
Cell junction, focal adhesion. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus.
Sequence:
MEATGVLPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNHLTTLHGDLSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSYNQLTECPRELENAKNMLVLNLSHNSIESIPNQLFINLTDLLYLDLGENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPALTALQTLHLRNTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSLPSAICKLTKLKRLYLNSNKLDFDGLPSGIGKLASLEEFMAANNNLELIPESLCRCTKLRKLVLNKNRLVTLPEAVHFLTEIEVLDVRENPSLVMPPKPADRAAEWYNIDFSLQNQLRLAGASPATVAAAAAAGSGPKDPLARKMRLRRRKDSAQDDQAKQVLKGMSDVAQEKNRKQEEGADARAPGAKVRRWDQGLEKPRLDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEALHGKFYEADCYIVLKTFLDDSGSLSWAIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDSDISYVEGGTASGFYTVEDTHYVTRMYRVYGKKNIKLEPVPLKGASLDPRFVFLLDRGLDIDVWRGAQATLSSTTKARLFAEKINKNERKGKAEISLLVQGQEPPEFWEVLGGEPAEIKKHVPDDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKTRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSLEGTEAQVFKAKFKNWDDVLTVDYTRNAEAVLQGPGLAGKVKRDAEKKDQMKADLTALFLPRQPPMALAEAEQLMEEWNEDLDGMEGFVLEGKKFARLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEERKEENEDEKAGAEGEDGEAAAAKQPEEDFQCVVYFWQGREASTMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFVIHRGRRRAAQGAPQPSLYQIRTNGSALCTRCIQINTDSGLLNSEFCFILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNSMFEASYSKQVINEGEEPENFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHLRSKEHERPRRLRLVRKGNEQHAFTRCFHAWSTFRKALA
The following text describes a protein:
Function:
Shuttles copper to the transport ATPase ccc2. Protects against oxygen toxicity (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MKYQFNVAMACDGCKNAIDRVLTRLGVEDKSISVEKQEVIVTTDKPYELVEQTIKKTGKEVRSGKVLE
The following text describes a protein:
Function:
Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG).
Sequence:
MNSLDLMMASVACIGECMVELRQAQGGHSAGQSAGQSAGQGGGLYSRGFGGDTLNTAVYLARLEVKVDYFTALGDDALSDEMIAAWNAESIGTRRVVRLPGKLPGLYMIQTDAKGERQFFHWRDSAAARQLMSLPETDELLNSLMSYDIVYLSAITLSIYDAPGRERLLAAIKRARLLGTRFVFDTNFRARGWPDRDVAREAFAAAFATADIVLTSTEDLLALYPGESRDQLMARIPSPELVFRLAEPVSLLRFPGGTSEVRAEPMTKPVVDTTAAGDSFAAAYIAARLAGSEPVEAAQAGHRLASLVICYPGAIIPGYAMPPKKRHRPAATRQATK