lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins (By similarity). Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate. By dephosphorylating PtdIns(3,4,5)P3 antagonizes PtdIns(3,4,5)P3 production by age-1/PI3K and thus, negatively regulates daf-2-mediated processes including dauer formation, longevity, fat metabolism, chemotaxis towards salt, thermotolerance and axon guidance. Similarly, promotes apoptosis during embryonic development by suppressing the recruitment of the prosurvival kinases akt-1/2 to the plasma membrane. In addition, regulates Z2/Z3 germline precursor cell cycle by maintaining them arrested at the G2 stage and by controlling their growth during L1 diapause. After sperm depletion in larvae and adult hermaphrodites, promotes germline stem cell quiescence and oocyte accumulation. By dephosphorylating ephrin-like receptor vab-1 on tyrosine residues, negatively regulates oocyte maturation downstream of vab-1 and upstream of mpk-1, independently of daf-2. Plays a role in postembryonic muscle arm extensions. Required for neurite outgrowth during AIY interneuron embryonic development. Mainly independently of daf-2, negatively regulates vulva induction probably by inhibiting mpk-1 phosphorylation. Both lipid and protein phosphatase activities are required for the regulation of vulva induction. Plays a role in gonad and germline development following the L1 diapause.
Subcellular Localization:
Perikaryon. Cell membrane; Peripheral membrane protein. Cell projection, axon. Cell projection, dendrite. Cytoplasm. Nucleus. Note=During vulva development, localizes to the cytoplasm and the nucleus of vulva precursor cells and of vulva cells at the Pn.p stage of L2 larvae. From the Pn.px to Pn.pxx stage of L3/L4 larvae, localization increases at the plasma membrane and becomes maximal at the Pn.pxxx stage of L4 larvae.
Sequence:
MVTPPPDVPSTSTRSMARDLQENPNRQPGEPRVSEPYHNSIVERIRHIFRTAVSSNRCRTEYQNIDLDCAYITDRIIAIGYPATGIEANFRNSKVQTQQFLTRRHGKGNVKVFNLRGGYYYDADNFDGNVICFDMTDHHPPSLELMAPFCREAKEWLEADDKHVIAVHCKAGKGRTGVMICALLIYINFYPSPRQILDYYSIIRTKNNKGVTIPSQRRYIYYYHKLRERELNYLPLRMQLIGVYVERPPKTWGGGSKIKVEVGNGSTILFKPDPLIISKSNHQRERATWLNNCDTPNEFDTGEQKYHGFVSKRAYCFMVPEDAPVFVEGDVRIDIREIGFLKKFSDGKIGHVWFNTMFACDGGLNGGHFEYVDKTQPYIGDDTSIGRKNGMRRNETPMRKIDPETGNEFESPWQIVNPPGLEKHITEEQAMENYTNYGMIPPRYTISKILHEKHEKGIVKDDYNDRKLPMGDKSYTESGKSGDIRGVGGPFEIPYKAEEHVLTFPVYEMDRALKSKDLNNGMKLHVVLRCVDTRDSKMMEKSEVFGNLAFHNESTRRLQALTQMNPKWRPEPCAFGSKGAEMHYPPSVRYSSNDGKYNGACSENLVSDFFEHRNIAVLNRYCRYFYKQRSTSRSRYPRKFRYCPLIKKHFYIPADTDDVDENGQPFFHSPEHYIKEQEKIDAEKAAKGIENTGPSTSGSSAPGTIKKTEASQSDKVKPATEDELPPARLPDNVRRFPVVGVDFENPEEESCEHKTVESIAGFEPLEHLFHESYHPNTAGNMLRQDYHTDSEVKIAEQEAKAFVDQLLNGQGVLQEFMKQFKVPSDNSFADYVTGQAEVFKAQIALLEQSEDFQRVQANAEEVDLEHTLGEAFERFGHVVEESNGSSKNPKALKTREQMVKETGKDTQKTRNHVLLHLEANHRVQIERRETCPELHPEDKIPRIAHFSENSFSDSNFDQAIYL
The following text describes a protein:
Function:
Cell cycle regulator.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Nucleus, nucleoplasm. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the cell membrane of epithelial cells. Its subcellular localization dynamically changes during cell-cycle progression. At the prophase, it concentrates at the nucleoplasm. In the metaphase cells, it becomes diffusive in the cytoplasm and some is concentrated at the mitotic spindles and spindle poles.
Sequence:
MQRHKELYKEQSLVLSPRNHCQENRDRLQAARAKKREDCFYQNRIISVSPTPVKIKQLAAAQAALTQENVAPKLESPERLDTKPAELLKESNPKVSRQKLYLQRYMEWKIAKTKEHKQQDQKRRGAAINVPTVKQSKALPKSQTFRVPDNLASAKQKEAAPMFQPPKRCSLYMIANPTGKGKAAEPIKPSIPKPTSAAAPPSSNTVAASSALARHKSAASATKIVPAIRQNNNPVALARQKAAARPIPNTTKQTTSVRQPGIEAKKITTTIPRPTPATVTKAKTPGIRQQPPVVSTKPRLPEPPAPRTARLPNVLSKPFEKPLGNKAPVTRRANVVKPQPIRGGGGAAAKFKDTAGATSKAASHSIRMKATKIKSQYTRLQDNVRKLPQLKAELLHAATLDIPPLTPLDDIHNPFIDQATSTQCKSNNSSGHLLEAFGDTILLSPVAPVKAEGESSVKRQLLPEGKKEASGPVAKKKFDFTRYSVANSPAEDSLILDPQQTTVKEDTGDSTLVPEGTKTPPRRESNGMPNYLSPFVSVSRGKVNSRCEKEKRNSFYLSNEESPLEVRRAIESVLYFRLQLENEITRLQALCAEWEAYSKENEARLQETGGIDMINVTIGQTRLLTTKKMMQFSGLIDRCEAGATGKNSQPNDGSEDSKPVQAEDLEGWWDMLRLQSENVDKRFDNLKRWKANDWLDPDAVAEEPKQPKPKPKISRNMKIKSKAKPSSNLQQFLRKAHANMKKTKVEEPTLEDGLPATSSRHSSPRVIVVRNRRSFSPARTVLRMSTGEGRQSIAPNALLKSAILAAAEQNAAKTPPPKPRTSILKTPGTTKRQNRGVLFSAKKSVRRFQFTYEEGNISNDETVGADKLEDCEEDMSLEASTESGSLEQNPGRDSNQENEATPRTYTLRNRRVNLRPSSEFM
The following text describes a protein:
Function:
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
Sequence:
MSNSNKLIAEKNGSRYGRMIHPWLRKKQDMLADTPSRREGMTYEEELSKRQQGGVFIFDIAMQLTHGKGEHGLSGVAATLFNRFFNVHSLKRCDFRDVAAACVFLAGKNEDAPKKLKYVVTQLWQFKYPHNKQFQSEQHFLDQCNVVTLIEDVLLKTISFDINVDLPHQYVLKLMRDVEKGRNVYKDMVKTAYYMATDVLIITDWSVRYSCASIATACVNIAAFFHNINMDDIVPFELSDRWYRLEDQSMTREEVEAMTKEFLDIFSRNPQFHIGSLKKIDPLGKVKIVGMPPQVSSTVTPSGSSSNLKKIDLESYKGRPKPLSNSSDSPSTRPSFLPDVKNQKVVEQELMEQRMKEAAQQKIHRNGHRPSSSSHPLHHHSTSSSASNNSNHQNRSSSGLSAHQHQKPYNEDSRSAKRSMMYEETNSSKKPRIDYKMSFVASSSTTIATMHNDHFSQTTHQQNISTYARGVNEMMLNQVAPPPLMSVSAQPSTYQKMCMEYQRNPADSRHTMSSTQQISPPDEPSPPVSQILLPPPPPPPILPPRLDEMEEGELV
The following text describes a protein:
Function:
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Is a critical central regulator of gonadal function.
Subcellular Localization:
Secreted.
Sequence:
MRIMLLFTAILAFSLAQSFGAVCKEPQEEVVPGGGRSKRDPDLYQLLQRLFKSHSSLEGLLKALSQASTDPKESTSPEKRDMHDFFVGLMGKRSVQPDSPTDVNQENVPSFGILKYPPRAE
The following text describes a protein:
Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Sequence:
MEEERRPYPPQPPVCWIRLPDVCLQRVFWWLGDRDRSRASLVCRKWNQIMYSANLWRYRTITFSGRPSRSHATEFESALWYIKKFGKYLEHLEIKFTNPYNSILTKKFQLTMRGLLSYLGRCNNRLKSLSIQHLELDRMVWRNHIRTSFIKSLSFFLRKMSKHLDCLNLRGAKVSLDQGCSILASLGRLQSASFTSVLNIEDYFSHHLSVYGHPQFNDIMATFRRLAVLTLNYNCVSDELLEILCKNNAGSLWTLNIKCHVHDPHGQVVWGLSWAKLARQATNLKVNFFFERVMKYERLTRILLHEIPIRSISLRSCYFSDPDWSMRPTLTDLLPNYRKTLQKLTFEFNNNHETLDEELLQLILICEKLYYFKIWAFLDVKFVERILEYQEKGKCQLQTLKVK
The following text describes a protein:
Function:
DNA polymerase II participates in chromosomal DNA replication.
Subcellular Localization:
Nucleus.
Domain:
The CysA-type zinc finger is required for PCNA-binding; The CysB motif binds 1 4Fe-4S cluster and is required for the formation of polymerase complexes.
Sequence:
MGRPFNGNNTHVVKQRSDEFERRRLERIEQLGQKFAAVERRDAIDDRMGFTRFSGDEKRVGWLVNMHETLLQSETAERGLAAVDYYFYDEEGGNFKSTVVFRPYFFVICKPHTEHAVKDLMEKMFERVLASTEIVTKEDLNLTNHLTGKKRKAVKLEFHNSEDLSSTRFTLSKIVDRQTQQTEQHLNIYELEGDVDTSTDVESSITGIKEFDVPFETRVAIDLDIRVGNWYEVTKENDTAVLKHMVEREYRADPVVMAYDIETEKAPLRFPDSAVDRIMMISYMIDGEGFLITNREMVSEDIEDFEYTPKPEFPGNFTIFNEPNEKAVLEKWFEHIRDVCPTVMTSYNGDFFDFPFIDKRTAFHGMNLYDEIGWKKVEEERYECSYCVHMDCLNWVKRDSYLPQGSQGLKAVTKVKLSYDPKELDPEKMTPYARDHPQILAEYSVSDAVATYYLYMKYVHPFIFSLCCIIPLNPDAVLRKGTGTLCEMLLMVKAYEGRIILPDKHKPALERHYKGHLVDNETYTGGHVESLAAGVFRSDIMVDFDIDTNSIDELLVNLDETLEFCVTVEAGKKSSDFENLDEVRDQIIEQLQELKSNPKRSDYPLIYHVDVASMYPNIMTTNRLQPDSMVDEKDCAVCDYNRPDKTCARELEWARRVDYYPVSKGDVNNLKQGLVEEYSGGRFGNGSSVEISYDEGMTEREKFQKRKGWAGLSGQEQANKLKERVAAFSLKTKARKTDSETTVQKTIVCQRENPFYVDVVQEFKQRRIDYKTKAKRWNKEAASASDPASREEAKKMAITNDSMQLAHKVILNSFYGYVMRKGSRWYSMEMAGVTCYTGAKIIKIARQTMEGLGIPLELDTDGIWCMLPKTFPEKFKCKFKDGSSYELEYPCSIMNYLVHRDFTNHQYQKLNPETGKYDTHSENSIFFELDGPYKCMMMPTSTDKGKGLKKRYVVFDDRNKIVELKGFEVKRRGELSLIKKFQSQLWDTFLEGSNLVECYAAQARVAEAWLAVIDSRGKNLSDEELIDLVCENKSMSKPVHEYGSQKSTALTTARRLAEIMGDSILTGGKLSTKYIIAVRTKNSMPVPEAKKGSDEDSSTADRAIPTLVFETESLDEKLRFLKRWMGPRWESTDPRDVIDWMYYRERLATTINKLVVIPAILLGLKNPVRGCDPPEWASDIIKQRDNPIKQSTLSSYFVKGKLPTPEPILSEEDEVMEIQVGDIESIGTTPSPSRPPGVPARVVVSKRVRKTVEETDKSTPSLPHKAPDPFADYAAYIKYAKVKWKHQKAQRDRRAHLFGESDNGIASSWVSKNAHLAQDAWHLVSIHAAEKPGQVEASVIIGDKMQRVQINVPRKVYVGSREPLKWDKFTDVTNAMAVAEEEQPKYLYRAVMSEDMYQTEMTNPESPLKDPHVTKIYEADVSPDSRALIELGSTFHLDASTPGILSKGFTHGFEAKWFKSGDSRSYLQNSGLSYAHIVHVVSSAVEIFVITPTWDAPALVFVHQSSSSEKLPDISKEYARLRRGERYKQNMDDCTVFSFPDTMQYEVEYCSNHRRMLQKVSKACDSLSGSRNGQLVFALHSPDRNVDEKVAALARIPCIRLRPVPPSTAAVGWQRDLVRRLIASFLSHGANISYLVEMARYAKMPLCHVQDTRDVIDVSYARRLIQNSVVLWWSAALSTGGALTDQAEVPVANNPGLYTNICFEIKIEHLVLNALLQSAVIQDTEGDIHNELLSNAFNPHALKTLKMVVKEWWEHGDKKRPPQDLLDNFTVWVYAPESRLFSPQLLYHTQNLTKKTFLYLAQECRKHQAQLVYADQHKLVLQTEKTELQLVYSYSNYIVRQIRTHPILKYVSVDITRYWDTFLWMDKWNYGGYSSDVIVDPSKQSESLLMHWHIANFLPETLQQEFSKWVQEYIHLLRLRKYPENRTTDVDDMPSDTPMLTDGDKDDAALLSDKFFGKGVVSYLHPKLVRRVKLLAQKLSDVLSSGDSIDAFKFPVLPGSMIQPETNPVVEFAKYVCHIYGINAKANFEVQILLRDLLNIFDINEFSEEGTFRDPSMSLKLTNMMCFKCKNPCDLDLCKDSCCTKSGFRCPLCNSLYDMVIVEQRLVGQLQRMILEYETQDFRCDKCRRVKEYELTEFCPCSGSWVTIMSAEDVHKELSIYDRCARWFELKMLGSFLRQLGYV
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MMLGRGRWRALGSASTHIINAQSRVGEFAFKRFLSSQTAFSGLKSRGCFGVIVASHRPPERSALLEKELRGSQISKRLASTSKKKKEASESGDLMEAQEQPESQLTVGAKVVQAGKDVTYLGIIIVGFAVTGALLWYVFSELFLGFSPNRVYSDALKKVLANSEVVEELGEPIMGHGEETRRGRRRHVSFQEYVVDGEDYMRIKFYAKGSKRKGTVHVDVKKGSRGSFIYRFIFVEIPDYPSRTIIILDNR
The following text describes a protein:
Function:
Suggested to catalyze the deposition of the aromatic residues of suberin on the cell wall and thus play a role in cell-suberization.
Sequence:
MAAKVGIFAAILLVCAILSPLLASSFPNHRPEFLEHDSGKTDVTIHGDNNNVVHANVNDIAIPCSNYETRNERSLKEKKKKKNKNKKNKKEMNHHEHDFEAFNFEHPQIEGVRHGYPQVFPEHNVDPITKEHEEPEILEGLREGFYQNTCPQAEEIIRNGLIRAFQNDSTIAAAIPRLFLHDCFVKGCDGSILLDTTPTGGKIEKLSPSNGITVKGFELIDEIKAELEENCPGIVSCSDVLAYLSRDAFVASGLPHYEVSGGRRDGMESRVENVVGNLPLPDDTVDQMIQLFNRKGLNAEDLVVLIGAHSIGVAHCFNFLYRMDTPEKAQMVDPRLGNVMKFTCTGQMSTIAFDATTQYKMDSVFYKQLLMKKGLLESDQALTQDIRTRGLVQRFSNDEVGWFNKFGVAMNKLGAVEVLTGNQGQIRKQCRAVNL
The following text describes a protein:
Function:
Plays an important role in the control of DNA replication and the maintenance of replication fork stability.
Subcellular Localization:
Nucleus.
Sequence:
MAASQRATGCYKCGGTGHWARDCPADGKPDGKQEGEPAKDGQREWKEWKAPTGKKKQAFDVLGPKRIFTRPKLTEDVLLSKDKGIGYILQEFPKLMEIKGRGHEVGDLRRLLELYQRWHKMVFPSVTYSDFVEKVEKLGTKKRVRSTIRDLRHRIVNGEDNAYEPADVEPTAWGTAWEQQVDQNAAADGNEAWEKGPSPGQDGWETGIGAAPNDWGAATGVGGGPASWADDEPNGASDAGPAAVGGGLTAEQRARIEANKARAVALRRERAAKAAEGRAAEGEGVTEAEEHEPPPPGSNNPAAKSMRQRLADDTDDDDDVIRNEAEERVSQAAAHRATSEERSVAAQKKRARKEMLDRLAQRRGAAGQESSGSDGDAGGGRRRRPKRTDHPDGDKEGNHGAGRSNGQDERPDGRDERPNGRNERNERANGLEEGPNGLSDGVELGAGDGSDADAVESSAAEQTGGASGTQNGKRRRLLKTDVVAELCTQNGLEDALMDDVEAVGARAPARARRNVVLDSDDDE
The following text describes a protein:
Function:
Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
Sequence:
MVRDKMGKKITGLLDGDRVIVFDKNGISKLSARHYGNVEGNFLSLSLVEALYLINLGWLEVKYKDNKPLSFEELYEYARNVEERLCLKYLVYKDLRTRGYIVKTGLKYGADFRLYERGANIDKEHSVYLVKVFPEDSSFLLSELTGFVRVAHSVRKKLLIAIVDADGDIVYYNMTYVKP
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Mitochondrion.
Sequence:
MFANFRNCFKIKNSRLIYDNINKCLLTKEETNQLLKFIHLKWKPAKDQVQISFSRSSGPGGQNVNKLNTKVIVNLPFKQLESCIPMFLINHFKTCEMLRNYRIQNGIKIYSQKTRSQHKNIEDALNKISDLLNKSAETLYVPDTPPEKIARISILKKESNEKRLSEKKYKQKKKTQRRITMD
The following text describes a protein:
Function:
Displays bipolar ssDNA and dsDNA unwinding activities that require the same core catalytic residues for unwinding in either direction, the 3'-5' direction being more robust.
Sequence:
MFSILQGHAGFSRDLATGIWREIKAEDYTFAKRFSKEHPEGKPASMPFKFDVIEEHDPQSLAEMLPLMRRLTSDPHIVAVRGRCLAPKNNVRRKKGNFNVSNPSNIIAMDVDGILDTGGYDKFNLVGMARHIIKMLNSISEDMFPLDAGFIAHASSSAGLKPGIRMHLMLESNVKVTQGQLKFLFTSINDSSKQKFGFDIADLAYYSSVQLHYFADPLFSDGIVDPFKAESKPRLVYVKGSKVNLPNNLVDYETTRGEFKEEFYSLLDQIKGKKIASDKVEETISELEEADDGVYLRIIPKLYHRALEDGVDFAWLEREIKPALSEYIATKDNSRNIQDYFNNGRKQALKAFVNNSKREIPLNLKGVPLKKLEVDSPPEVPYLKINIVPPKGHITFVKASLGTGKTTAVTKWLDAGVLPGNFLAVTNTRALVSSNAKKFSAGQYDKSVDMLNFKRGAIDRMSTTIHSLHKFKSFIGQIDTIFIDECDAVMNDLLFAPVVKQRRECIQVLRDILMTAKTVILSDGDISAETIEAYGSLIDFDKPVAFYNHHRKMLSKAHAYEFPDESSIWVALQTSLEMGEKSILVSDCGPDELNEKGMALRRNTGALVKEIHSNSTSDVDIRRILDYTTNELIDQQIDCLLCSPSVTSGVDFNYFDNVFVITRTSNQAPNMRFQAIRRDRGAQNIYYFIDKSTSGFSAGSEQYNIDEGWLELAQQLYARRRELESRNYTSTLRYYLLDQGATIDIFSESWGTIEGAGKEYTEERIKAILHSTPDYCAPRHADAYEAKLLLVRYYHLESIKDVTVEHVEQYIKDKPNDRAAFFHKMHEMFWEDIKKCSNVTIKPFIEALKGKKKDFFLKTGQSANPKYARMYLGMMGIGKDMNTENIVDWYRTYCKIECMPIPFKFMTEEERAMAEEVMSELGATNEDA
The following text describes a protein:
Function:
Involved in the nuclear import of cdc25 and mcs1; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Involved in the nuclear import of cdc25 and mcs1. Mediates docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to repeat-containing nucleoporins. The complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, GTP-Ran binding leads to release of the cargo. The importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus envelope. Nucleus.
Sequence:
MSSGFPPEVLSPLLNLVQGLSSPDNTVRNDAEKSLSSDWISQRADLLLNGLAILAYQSEDPAVRSFCLVLCRRISFRTLPGDSELEVFSSISNESKQSLQSQLLACFVKESVPTVRNKLCDTIAEIARSIYDCQGEWPELINVIFNAVNSPDESFRESVFRTITSLPRLLSGQDSAVTPLFTTGLADPSIRVRISAARAYSAVILESKQSTRDQVIPLLPSLMNILPPLQQDRDSDNLADCLMAITEIAEVFPKLFKPIFESVIAFGLGIIKDKELDNSARQAALELLVCFSEGAPAMCRKSSDYTDQLVLQCLLLMTDVAGDPEDEAEELQEWLNTDDLDQDESDANHVVAEQAMDRLSRKLGGKTILPPSFTWLPRLIPSQKWSERHAALMAISSIAEGAEKLMKKELSRVLDMVLPLLADPHPRVRWAACNAVGQMSTDFAPDMQVKYPSRILEALVPVLESPESRVQAHAAAAMVNFSEEADNKVLEPYLDDILQRLLTLLQSPKRYVQEQAVTTIATVADAAAKKFEKYFDAIMPLLFNVLQQADGKEFRTLRGKTMECATLIALAVGKQRFLPVSQELIQILGNIQMGITDSDDPQASYLISAWGRICRVLGSDFVPFLSSVMPPLLVAATSKPDFTIIDDEVDESKYSEQDGWEFIPVHGQQVGIRTSTLEDKCTATEMLVCYAAELKADFDPYVNEVLTSVVLPGLKFFFHDGVRSACCKCIPQLLNARILASNRDPAKVNELWEPILRKLLDHIQNEPSVEMLADYFECFYQSLEISGLNLSPSSMEALVAAVDLQLKGFISRVQQREEEAKNGDIDIEEDEDMILAVENDQNLLNEINKTFSVVLKIHKTAFCPFWERLLPYMDGFLSGNDTVAKQWALCMMDDLIEFTGPDSWNYKDHFLPYLAEGIQSSEPEIRQAASYGIGVAAQHGGELYAEICSSALPALFKMLELPDARDEEQIYATENICVAICKICRFCSQRVQDLDKVVTYWINTLPVTHDEDDAPYAYTFLAELMEQNHVAVASQMPTIITILAETFASGVLRGRTLTRLMEASKVYLARFPADQVNSVIATLSVDNQRALSAHF
The following text describes a protein:
Function:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Subcellular Localization:
Secreted.
Sequence:
FPMGREPRTSALWAASALLLAALCLTEEAIRCPPCSEEKLARCSQPANCEETVREPGCGCCPTCALPKGAPCGVYSPRCGSGLRCYPPRGVDKPLHSLMHGHGVCTDEREVEQLMGAAEKEEQLNLDHPNNSHIPCSPQDKKCIQKQIARQQREKGSNQKTKNNREDPKPALAPCRADLQRALERLASHTRTHEDLYTIPIPNCDKNGDFNPKQCHPARDGQRGKCWCVDQKTGIRLTNPQDMRVDQSCQQLAADPQRK
The following text describes a protein:
Function:
The ERF2-SHR5 complex is a palmitoyltransferase specific for Ras proteins. Palmitoylates RAS2, which is required for its proper plasma membrane localization.
Miscellaneous:
MISCELLANEOUS: Present with 937 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein.
Sequence:
MCDSHQKEEDNANTSERALFFNYHEFSYSFYEDLGSEDAKPTEHDEDHKLCITHFPNVYAARGSAEFQVTRVVRVPRRFDESRSSLETPQFSTQLPGSEPAAIVGDDGTSFVRCGRYDIGDHVFGCSSVSPLSEYLSAAELAEVVHRVNGFLLREEGEVFGWRNLSGLLLDMLTGGLWSWVLGPLLSRPVFQESLALEQYVAQLNSPGGLLHERGVRLVLPRRSGCLSLDFVVPRPK
The following text describes a protein:
Function:
Has a dual role in the assembly of cytochrome oxidase subunit 1 (cox1). It has a regulative function on cox1 synthesis, acting as a translational activator specific for the cox1 mRNA, and it also binds to newly synthesized cox1 protein (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MSFLKNLFKKKSPTHELFHPLSRSPLTALRRRSEHIKQVYRCPISGKSVEYECPESGFPTHCNRTHWEQDKIHQSLIPKLRQINEDYHDLARPNPLPELLKLPGPMEEDEVVSLLSWDSFFYTRDFPKFQSSRTARHITSLLTYPMSIGAILHKNSPYNLKNGLTPQGLQSLTALRYMLHRPLSAQSTDPRPTRIFVLGATKECSLPPSIWLQGLNFLFPGRLFQLHFIGPEVVVPSKQPNLPSPLSLHFHQDYYHNLHRVGAFEPFDPYYDTFFLPMPLISHPLYSSSWIPTLHDLVSTRCSVWLTSPSSQRTTKDLEVLNNVLKDSIEPLLLPTVNKFASLGWSVDDSNLHEVYHANQEVFGFRALYYNVQNVSKE
The following text describes a protein:
Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, axon. Cytoplasmic vesicle. Membrane, caveola. Presynapse.
Sequence:
MALNGTAAELRSLGISAEISKDTSMEQKVSLGNAVLNNSMDCNGSEERNRSEFSSSDYVQKNWVALLISLVIIITVTGNILVIMAVSLERKLQNATNYFLRSLAITDMLLGILVMPVAMVTILYGYTWPLPRTLCPIWIYLDVLFSTASIMHLCAISLDRYIAIRNPIHHSRSNSLTKARVKIIAAWTISVVISMPVPVLGLHDHSKVFRNESCQLTDNNFVLIGSFVAFFVPLIIMVVTYFLTISALQSEATLCLDQLIVRPTWSSTIGLLPRGSVSSERLFSRSSICREGASRGSGRRSMQSISNEQKASKVLGVVFLLFVIMWCPFFVTNVMAVVCGSVCDEDLVGGLMNVFVWVGYLSSAVNPFIYTLFNKTYRAAFARYMQCRYHEERRPLQLILVNTIPPLAYSSSGLPLKVENSLRRKAEGSRSGSFTNTERSICGSTQNKQERDEVVSHL
The following text describes a protein:
Function:
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Sequence:
MEPKDLILNVIGSLYDIVKCCYGINGQYQMLVGEEDNGEDKNNVILSKKASEILKSLKIEHVFSNTVKKSVHMLETICYDCTNTLVLLIYSLFRECVVIMEKGIHPISLVYSLQNSFTTQIEPILKSLRIPLIPSLENIDTIDNDEILKLKLNQINLDLLYKTIYSIINTKLDNSTVLNYSGDNNDNDDSNNNNDNIVVSNIAGLCLETIKSLYINNKDFTIKDIMNHRISFQDQVIIYPRLLKNNDLFDLNIISKFLSNGFILDNNNSNNNNNLNNFKNNYSGSTNFILFINEDLKLKSNNSDAPQSGLTKSSGQDKKEKTKLVFHSAQERTELLEYEKTILKNKVFKICKYIEKIVELDNSSAAMIVLVFNSIDEYSKSLFDTNSTNSSKFLIFDNINQQHIRIINKSLGINCINSVDSIFSKEGLENKEYLLKIKRNFIGGCSKIQYRVFTNQFEFSKLVNPVSPLISVEIFAPSNHILRQRVGSFVTGMGIGKCCLEDLFILPSASSPEFSIIGSLKRQIESKKLSFVDQQTFEALVKSIETIPITLLSNQNKPVLKILDLFYKTLNNNNQEAAAVGINLISVDSDSDGDNKQYFINPSDFGIFETYRGKTQVFRFAIDIVCLLLKIDQIIQPQPPLQQKQQQPPPQQNQQQTQQKKEYTEFKTPDIITDAIEKDKIEKTKKQNEIFYSKEEIEKRKRLDRKFNTNPFNK
The following text describes a protein:
Function:
Has a crucial role in plant growth and development, possibly by influencing mitochondrial division.
Sequence:
MVGTKVSAVSRKTNTTVHEVLGVMTKGDTQMCFFDTPGLTLTCSGFPHKDLKARVESAWSAVKLYDVLIVLFDVHRHLTRPDMRVTKLIERMGAQAHSGQKRVLCMNKIDLLEKKKDLLQVANQFKDLPGYDRYFMISGLKGSGVKDLSQYLMEQAVQRPWDEDPMEMSEEVMKNISLEVVREKLLNYIHQEIPYEIEHRLMGWKELRDGSLRIEQHLITHKQSQRKILVGKKGSKIGTIGIEANEELRSIFKRDVHLILQVRVK
The following text describes a protein:
Function:
mRNA stabilization factor specific for the 0.95 kb oli1 mRNA. Also involved in oli1 ring formation (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MPTYRFNYLRFNKLCVSFFRSKFDKRPFASQKFPENLVPDNSSNDANSQPEEVSSKKPWYVDEKHNLFPKKAHFDAVALPPIPKGAPNFLADVLNLLKKKYYATDLSFVNSPADSFWCDSDLILLASCNCGSEVVSATNGLLRLLKQKNVGPVNVDGLTSASRRKILERRMRKRSNLSNRQLNTSENNWTCLSIENFGISIHVITKNFREYYKLDNIEHVKDETLYSDLEHGKQSRVSLTSKSTPDNSLPPNFINNHSNVFRRSFHTCNFSLKSAASLYCDTQDILLNVNSQNLTSTLEKYKKMHLQNPNNFSLDFTLSIFERLRKDSSLQLTTKDINTLFSTIALSPTKLSMASKHSKNLVSERMLYLSLMYKSLVDLKTIDSFSLKLLFLKFMICSCMVKGESNFFLDNRIFLLERIMNRYGIPMTIDTFLLMQFILAKSNRWSEVWRRWDNLRKAGVVFNERLYNHVYLLAFESKNERVINYVLTNIFEDMVSQSPPIPASKLMATSLKKCVQSLPEKYAHSFPSVRNYIAKMENSMTH
The following text describes a protein:
Function:
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
Subcellular Localization:
Cytoplasm.
Sequence:
MEEVQKKQAISLSEVKEILGKVDPEEMDQIQRWTYDYVSKFVSLDPKDAKEMKKKLIKECELTEDEAVEIVNIRPTSMAELRSFTFGWKKLILAETLEKMLKIIKEHS
The following text describes a protein:
Function:
Catalyzes the isomerization of sulfoquinovose (SQ) to 6-deoxy-6-sulfo-D-fructose (SF). Can also catalyze the interconversion of SQ and sulforhamnose (SR). In vitro, can also catalyze the interconversion of mannose, fructose and glucose, but has extremely low activity with glucose.
Sequence:
MKWFNTLSHNRWLEQETDRIFNFGKNAVVPTGFGWLGNKGQIKEEMGTHLWITARMLHVYSVAASMGRPGAYDLVDHGIKAMNGALRDKKYGGWYACVNDQGVVDASKQGYQHFFALLGAASAVTTGHPEARKLLDYTIEVIEKYFWSEEEQMCLESWDEAFSQTEDYRGGNANMHAVEAFLIVYDVTHDKKWLDRALRIASVIIHDVARNGDYRVNEHFDSQWNPIRDYNKDNPAHRFRAYGGTPGHWIEWGRLMLHLHAALEARFETPPAWLLEDAKGLFHATIRDAWAPDGADGFVYSVDWDGKPIVRERVRWPIVEAMGTAYALYTLTDDSQYEEWYQKWWDYCIKYLMDYENGSWWQELDADNKVTTKVWDGKQDIYHLLHCLVIPRLPLAPGLAPAVAAGLLDINAK
The following text describes a protein:
Function:
May function as sterol isomerase.
Subcellular Localization:
Lysosome membrane; Multi-pass membrane protein.
Sequence:
MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGAAAVVLLLVALLARVLVKRKPPRDPLFYVYAVFGFTSVVNRIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHYLMYLVMVAAIAWEESYRTIGLYWVGSIIMSIVVFVPGNIVGKYGTRICPAFFLSIPYTCLPVWAGFRIYNQPSENYNYPSKVIQEVQAKDLLRRPFDLILVLCLLLATGFCVFRGLIALDCPAELCRLYTQFQEPYLKDPAAYPKIQMLAYLFYSVPYFVIALYGLVVPGCFWMPDITLIHAGGLAQAQFSHIGASLHARTAYVYRVPEEAKIIFLALNIAYGVLPQLLAYRCIYRPEFFIKTKADEKVE
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MLERDAESAAGDTDPRPAGKEPVTKRGAPHQGPPQTPSQSVPGPALSAGAPSRPRRRPPPQRPHRCPDCDKAFSYPSKLATHRLAHGGARPHPCPDCPKAFSYPSKLAAHRLTHSGARPHPCPHCPKAFGHRSKLAAHLWTHAPARPYPCPDCPKSFCYPSKLATHRHTHHATDARPYPCPHCPKAFSFPSKLAAHRLCHDPPTAPGSQPAARHHCSSCGQAFGQKRLLLLHQRSHPAAESQGEPE
The following text describes a protein:
Function:
Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase. Essential for centriole amplification and is required for cep152 localization to the deuterosome.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to centrioles and deuterosome.
Sequence:
MDSTEDRETPLKDQIRRLTNENVQLQDRNERLYAKLGELQDKMGKLAGSKTDLSSKLVLSEEEKLKISKELIELQIETNKIREHYEAETFELKNTILTLENRLMSLELQKEKLAGEHESVKERLQAVDANRKELADEYIVLKSNYLALSKEHEKEVAKNDELSMELLNLASRRGQDETYSQSRALVNEATAELDRVKAMVNRLSARNIKPEDLVATEYERQKLERNLLGNQDHIREEIENMKKIHETQQQRLEERIIAMGKELQEAKRAIRNTQHKMAEQSAVLLTSQSQLQETEAQNSHLQLQLKELNEEYRSRLNRYIQDLADYVDGTARSKGDGTRMKHFVDNMLSDIKASHRSREEQLAGAARQYKKRMQNLIKKHQSLLIAYRMQREQLLASGNQDVEPGPPEHHFTITDPELQSQVGLELNRLREDKARLETQIHDLKEKKRLSDAGTSNQHVEHGGKLQEESWAEIRKQLREFTHNTQEELERERSQLLSRALVAEEQVAELQDYVDKHLARYKQEILRLRKLLGNEEQRAVSADAPQSLLIRALRRNSHEM