lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Adhesion G-protein coupled receptor (aGPCR) for steroid hormones, such as dehydroepiandrosterone (DHEA; also named 3beta-hydroxyandrost-5-en-17-one) and androstenedione. Involved in a signal transduction pathway controlling epididymal function and male fertility. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG2 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Also able to couple with G(q) G proteins in vitro. May regulate fluid exchange within epididymis.
Subcellular Localization:
Apical cell membrane; Multi-pass membrane protein.
Domain:
The Stachel sequence (also named stalk) in the C-terminal part of the extracellular domain (ECD) functions as a tethered agonist. In the inactivated receptor, the Stachel sequence (also named stalk) is embedded in the GAIN-B domain, where it adopts a beta-strand conformation. On activation, the Stachel moves into the 7 transmembrane region and adopts a twisted hook-shaped configuration that forms contacts within the receptor, leading to coupling of a G-alpha protein, which activates signaling.
Sequence:
MLFSGGQYSPVGRPEEVLLIYKIFLVIICFHVILVTSLKENGNSSLLSPSAESSLVSLIPYSNGTPDAASEVLSTLNKTEKSKITIVKTFNASGVKSQRNICNLSSLCNDSVFFRGEIVFQHDEDHNVTQNQDTANGTFAGVLSLSELKRSELNKTLQTLSETYFIVCATAEAQSTVNCTFTVKLNETMNVCAMMVTFQTVQIRPMEQCCCSPRTPCPSSPEELEKLQCELQDPIVCLADQPHGPPLSSSSKPVVPQATIISHVASDFSLAEPLDHALMTPSTPSLTQESNLPSPQPTIPLASSPATDLPVQSVVVSSLPQTDLSHTLSPVQSSIPSPTTPAPSVPTELVTISTPPGETVVNTSTVSDLEAQVSQMEKALSLGSLEPNLAGEMVNRVSKLLHSPPALLAPLAQRLLKVVDAIGLQLNFSSTTISLTSPSLALAVIRVNASNFNTTTFAAQDPTNLQVSLETPPPENSIGAITLPSSLMNNLPANDVELASRIQFNFFETPALFQDPSLENLTLISYVISSSVTNMTIKNLTRNVTVALKHINPSPDDLTVKCVFWDLGRNGGKGGWSSDGCSVKDKRMNETICTCSHLTSFGILLDLSRTSLPPSQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLIFLLDSWIALYNTRGFCIAVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGIPAVVVSIVLTISPDNYGIGSYGKFPNGTPDDFCWINSNVVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCAAKENVRKQWRRYLCCGKLRLAENSDWSKTATNGLKKQTVNQGVSSSSNSLQSSCNSTNSTTLLVNSDCSVHASGNGNASTERNGVSFSVQNGDVCLHDLTGKQHMFSDKEDSCNGKSRIALRRTSKRGSLHFIEQM
The following text describes a protein:
Function:
Involved in the fermentation of L-phenylalanine via a Stickland reaction. Required for the activation of the (R)-phenyllactate dehydratase complex FldABC. Only in the oxidized state, FldI exhibits significant ATPase activity, which appears to be essential for unidirectional electron transfer. This protein is extremely sensitive towards oxygen.
Sequence:
MADIYTMGVDIGSTASKTVVLKNGKEIVSQAVISVGAGTSGPKRAIDSVLKDAKLSIEDLDYIVSTGYGRNSFDFANKQISELSCHAKGVYFDNNKARTVIDIGGQDIKVLKLADSGRLLNFIMNDKCAAGTGRFLDVMSRVIEVPVDELGKKALESKNPCTISSTCTVFAESEVISQLARGVKTEDLIAGICKSVASRVASLAKRSGIEELVVMSGGVAKNIGVVKAMEAELGRDIYISKNSQLNGALGASLYAYESFQKERS
The following text describes a protein:
Function:
Iron-regulated vacuolar transporter that mobilizes stored heme from the vacuole to the cytosol in response to iron deficiency.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MITANKGLSLVLLIPNLFALVSGGLQYVFDVRRRIFRPHFSQFWTIWMKFFSIALVIITQIYVGYKTKNIGWNFFSVVTYCFVLFLQFAEQSTLRVPMASLLIFWLLKVVTSLLILLFSPYIAITSMARLLTLITLFCSLVCFISEVYVPPCNRVWYSDDTNEVEEKGIRPSEVRYANIFSKLSFSWISSFIKFGYTNYLKESDVWLLPPDERSGNLIIGFEDWWIYHSKNKRRSLFLWKLLFFNHWKLVALITITKLIQDVLAFVQPTLIQKTILFISSYTSPNPESPSRGFIIAILVLVANFLQTLLLQQYNQLIMLLGMRWKTELLASIYRKSLLLSSSARQNRSIGDIINYMAVDTQKISDLPIYLFIIVSGPFQIALALSNLYHLMGYSAFTGVAASVILFPCNIIVANVYKKFQSILMKNKDSRSKLMTEIINNIRSIKLYAWETPFLQKLLHIRNTKELSMLKKIGFITAIGDFAWIFTTIIVTTVAFGAFIIFHGKTQALTADIVFPAVSLFNLLQFPLAMLPTVISSLLEASVSVSRIYEFLIAQELDYNGVQRFPATEIPHEICLEIKSGTFSWSKKTLKQQVTPTLRQINFVAKNGELTCIFGKVGAGKSSLLEACMGNMYKNSGSVFQCGSLAYAAQQPWIFDATIRENILFGSEFDPELYEKTIHACCLKRDFEIFTEGDQTEVGQKGASLSGGQKSRISLARAIYSQADIYLLDDVLSSVDQHVSRDLIKNLFGPEGFLRTHCVVLTTNSLNVLKEADSIYILSNGKIVEKGNYEHLFVSTNSELKQQLSEFNDEKDTQPLPEHTTSYPSTQISLAPSIHVEGLETYSSSERKDSSNKYKSRKRNPIRQKVTEDDKGKCVAQTDELVQRGKVKWHVYWMYFKSCSIGLILLYFFFIISGIMMNVATNVWLKHWSEENGKSSSELNPSPYFYLGIYLFFGFLSCAFISSSSLTMTVLCGIRSGRYLHDSMLKTILRAPMGFFETTSSGRILNRFSNDVYKVDEVVSLTFMFFFRNSIQVLFILGVICYSAPLSLLLIVPLFFLYLYNRAYYVRTSRELKRLDNVTRSPLYAHVQESLSGLSTIRAYGMQETFVEENDLRIDTNHRVWFMFFSSSRWQAIRVECIGDLIIFCTAFYGILSAIKGSPNPGLVGFSLSYAIQITQGLSFIVQQSVDAENNTVSVERILEYINVKSEAPEIIPENRPPCEWPTDGAVSFNHYSAKYREDLSFALNNINIEISPREKIGIVGRTGAGKSTLAMALFRIIEPTEGKIEIDNEDITKFGLYDLRSRLSIIPQESQIFEGNIRENLDPNHRLTDKKIWEVLEIASLKNCISQLEDGLYSRVAEGGANFSSGQRQLICLARVLLTSTRILLLDEATASVHAETDAIVQQTIRKRFKDRTILTVAHRINTVMDSDRILVLDHGKVVEFDATKKLLENKDSMFYSLAKESGLI
The following text describes a protein:
Function:
Putative carrier protein indirectly involved in the uptake of malate and fumarate to the vacuole, probably by regulating the energization across the tonoplast. Uptake of malate to vacuoles is inhibited by citrate and by the uncoupler carbonyl-cyanide m-chlorophenylhydrazone, but seems to be not affected by sodium. Critical for pH homeostasis.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Sequence:
MNGGDVTVAGSDDLKSPLLPVVHNDEPFERQTVGQQLRTIFTPKNCYIALGPLLCAVVCLCVDLGGDETTTARNMLGVLVWMFAWWLTEAVPMPITSMTPLFLFPLFGISAADDVANSYMDDVISLVLGSFILALAVEHYNIHRRLALNITLVFCVEPLNAPLLLLGICATTAFVSMWMHNVAAAVMMMPVATGILQRLPSSSSTTEVVHPAVGKFSRAVVLGVIYSAAVGGMSTLTGTGVNLILVGMWKSYFPEADPISFSQWFFFGFPLALCIFVVLWCVLCVMYCPKGAGQALSPYLHKSHLRRELDLLGPMNFAEKMVLAVFGGLVVLWMTRNITDDIPGWGRIFAGRAGDGTVSVMMATLLFIIPSNIKKGEKLMDWNKCKKLPWNIVLLLGAGFAIADGVRTSGLAEVLSKGLVFLETAPYWAIAPTVCLIAATITEFTSNNATTTLLVPLLIEIAKNMGIHPLLLMVPGAIGAQFAFLLPTGTPSNVVGFTTGHIEIKDMIKTGLPLKIAGTIFLSILMPTLGAYVFASMGGV
The following text describes a protein:
Function:
Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs).
Miscellaneous:
MISCELLANEOUS: Present with 178 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MNFVTCHVQMRLLLQRRLVRLRESELFRPQTSLSTFKRHASQKTRPIQKCSRKYARILLLSVLVPYTGYAFYVSLATVKQIDLRNEMCQRLEENNNEVTYKGSLLKYSPLEVLGRFENPFEEYRIQTVFEFFANRVFELFERNRGGIPRDVHQMNKLMPVHKPTWGPNLVDVDPAEETALPLECKVLDELHIPTAVEENEGSKCPVYNTWLGQSCNYTVYNGLRILTDPLFSDFLIHKTLGPKRITQMPSQITEVPKPDIILVSHNHPDHLDLESLEYWSGKDSPLWIVPKGMKSYMTSNGCDNVLELSWWETLQVKKNNEIYHISATPAMHWSGRSLLDTNKSLWCSFLLTHHGNPILFHAGDTGYVKDLFVRIKERFGKGCKLALLPCGQYCPEWHQKPRHINPQEVLKIMKDLEARNVLGVHWGTFVLSGEYFLEPKEKLEMLAEWGGFKDRCYCPELGKTECFD
The following text describes a protein:
Function:
Involved in the system for phosphate transport across the cytoplasmic membrane; Part of the ABC transporter complex PstSACB involved in phosphate import.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MKKYGIVAIISILVVALLFAGGCAKKNEQATPQNGQTTKEGKITLAGSTALLPLAKQAATLYMEKNPKVTVNVSGGGSFTGLRQVIAGAVDIGNSDVDAEKDPETAGKGLVDHQVAVAPFVIIVNPDVKVDNLSKEQLADIFTGKITNWKEVGGNDAKITIIHRAKSSGSRKVITDLVLDGKEFTDKAIIQDSNGAVRKAISQTPGSIGYIDAAYIDNSVKVLKYNGVEYTPENVYNKKYTLYAYEHMYTKGEPTGVVKDFLDFVLSDEFQNNYVEKLGFLSISKMK
The following text describes a protein:
Function:
Plays a critical role in recombination and DNA repair. Helps process Holliday junction (HJ) intermediates to mature products by catalyzing branch migration. Has replication fork regression activity, unwinds stalled or blocked replication forks to make a HJ that can be resolved. Has a DNA unwinding activity characteristic of a DNA helicase with 3'-5' polarity (By similarity); Plays a role in recombination surveillance and repair of double-stranded (ds)DNA breaks in the mitochondrion. May be able to dissociate D- and R-loops (Probable). Able to complement UV sensitivity of a recG deletion in E.coli.
Subcellular Localization:
Plastid, chloroplast. Mitochondrion.
Domain:
The first 208 codons are able target to both the chloroplast and mitochondrion.
Sequence:
MAAVTLSPCSMCCGSRRLRSVIVIQAQRGNWNRIRLSNFFFSKVWNISYRSKHKYSDNLLEQVEKYASARLENQSKLITKVAALMECDNVDDFIDKKSDEQVKKDLVLACKRFPSIILGDSRPVELYSNSKSYGESSSILKTPTDNSFLPTPMHGGWFDPDNLSRTLSSFCPELLQNDDSSDPREDILDDGSSFTSKTATSEVEATSDDVFAAQRFLATSIDSMPGLSKRHSNQLDSCGFHTMKKLLHHFPRTYADLQNAQVDIEDGQYLIFVGKVLSSKGVRASSSFSFLEVIVSCEVSGRDRTPEDLSHNAEDKAGKSIFLHLKKFFRGTRFTWQPFLNSIQEKHKVGDLVCISGKVKSLRAEDHFEMREYNIDVLKDEEESSHRAQGRPYPIYPSKGGLNPKFLSDVISRALRVLPANMDPIPKEITKVFGLPSLNDAYVGIHEPKTLDEADLARKRLIFDEFFYLQLARLYQMLQSLGTKIEKDVLLEKFRKPVLNSVYIEEWSTLTKSFLKALPYSLTPSQLSAVSEIIWDLKRPVPMNRLLQGDVGCGKTVVAFLACMEVIGSGYQAAFMAPTELLAIQHYEQCRDLLENMEGVSSKPTIGLLTGSTPAKQSRMIRQDLQSGAISFIIGTHSLIAEKIEYSALRIAVVDEQQRFGVIQRGKFNSKLYGTSMISKSGSSDSDDTSKADLSMAPHVLAMSATPIPRSLALALYGDISLTQITGMPLGRIPVETHIFEGNETGIKEVYSMMLEDLKSGGRVYVVYPVIDQSEQLPQLRAASAELEIVTKKFPKYNCGLLHGRMKSDDKEEALNKFRSGETQILLSTQVIEIGVDVPDASMMVVMNAERFGIAQLHQLRGRVGRGTRKSKCLLVGSSTNSLKRLNMLGKSSDGFYLANIDLLLRGPGDLLGKKQSGHLPEFPVARLEIDGNMLQEAHIAALNVLGDSHDLEKFPALKAELSMRQPLCLLGD
The following text describes a protein:
Function:
Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response. Mediates the uptake of various enveloped viruses via sialic acid recognition and subsequently induces the formation of intracellular compartments filled with virions (VCCs). In turn, enhances macrophage-to-T-cell transmission of several viruses including HIV-1 or SARS-CoV-2. Acts as an endocytic receptor mediating clathrin dependent endocytosis. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis. Plays a role in the inhibition of antiviral innate immune by promoting TBK1 degradation via TYROBP and TRIM27-mediated ubiquitination; (Microbial infection) Facilitates viral cytoplasmic entry into activated dendritic cells via recognition of sialylated gangliosides pesent on viral membrane.
Subcellular Localization:
[Isoform 1]: Cell membrane; Single-pass type I membrane protein; [Isoform 2]: Secreted.
Sequence:
MGFLPKLLLLASFFPAGQASWGVSSPQDVQGVKGSCLLIPCIFSFPADVEVPDGITAIWYYDYSGQRQVVSHSADPKLVEARFRGRTEFMGNPEHRVCNLLLKDLQPEDSGSYNFRFEISEVNRWSDVKGTLVTVTEEPRVPTIASPVELLEGTEVDFNCSTPYVCLQEQVRLQWQGQDPARSVTFNSQKFEPTGVGHLETLHMAMSWQDHGRILRCQLSVANHRAQSEIHLQVKYAPKGVKILLSPSGRNILPGELVTLTCQVNSSYPAVSSIKWLKDGVRLQTKTGVLHLPQAAWSDAGVYTCQAENGVGSLVSPPISLHIFMAEVQVSPAGPILENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAHSHTLRLHLATRADTGFYFCEVQNVHGSERSGPVSVVVNHPPLTPVLTAFLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGPNSLRLEIRDLEETDSGEYKCSATNSLGNATSTLDFHANAARLLISPAAEVVEGQAVTLSCRSGLSPTPDARFSWYLNGALLHEGPGSSLLLPAASSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAAGAGAGRRGLLLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLRVEIHNPLLEEEGLYLCEASNALGNASTSATFNGQATVLAIAPSHTLQEGTEANLTCNVSREAAGSPANFSWFRNGVLWAQGPLETVTLLPVARTDAALYACRILTEAGAQLSTPVLLSVLYPPDRPKLSALLDMGQGHMALFICTVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQAKAEANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPELQEGQAVVLSCQVHTGVPEGTSYRWYRDGQPLQESTSATLRFAAITLTQAGAYHCQAQAPGSATTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLEDEGVYICEASNTLGQASASADFDAQAVNVQVWPGATVREGQLVNLTCLVWTTHPAQLTYTWYQDGQQRLDAHSIPLPNVTVRDATSYRCGVGPPGRAPRLSRPITLDVLYAPRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANTSLELRLEGVRVILAPEAAVPEGAPITVTCADPAAHAPTLYTWYHNGRWLQEGPAASLSFLVATRAHAGAYSCQAQDAQGTRSSRPAALQVLYAPQDAVLSSFRDSRARSMAVIQCTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVARNALRLQVQDVPAGDDTYVCTAQNLLGSISTIGRLQVEGARVVAEPGLDVPEGAALNLSCRLLGGPGPVGNSTFAWFWNDRRLHAEPVPTLAFTHVARAQAGMYHCLAELPTGAAASAPVMLRVLYPPKTPTMMVFVEPEGGLRGILDCRVDSEPLASLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGEYICSASNVLGSASTSTYFGVRALHRLHQFQQLLWVLGLLVGLLLLLLGLGACYTWRRRRVCKQSMGENSVEMAFQKETTQLIDPDAATCETSTCAPPLG
The following text describes a protein:
Function:
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
Sequence:
MAKYNEKELADTSKFLSFVLRHKPEAIGIVLDREGWADIDKLILCAQKAGKRLTRALLDTVVATSDKKRFSYSSDGRCIRAVQGHSTSQVAISFAEKTPPQFLYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKRGLPFWQAENGVWLTSTVAVEFLEW
The following text describes a protein:
Function:
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
Subcellular Localization:
Nucleus.
Sequence:
MLKHNKVVPVVVFDGARLPMKAGTEAERRRNKNNSLEEARAKLAAGDERGAEEAFQRSVDITPQMALQVMKYLRREGVDFIVAPYEADAQLAALASAGKENGGIAAVITEDSDLLAYGCSTVLYKMDKYGNAEEISTERLFSSIGHGSQGPSQASSGRQQGGTCLSFRHFNQELFLGMCILAGCDFLPSIPGIGISKAHAVVNKYRNVDRALSRLKLDAKLVVPPGYAREYARARATFAHARVYDPASKRLVHLNPLPEGFAEGFGGDIDFLGPDMSPSTARAIAEGRVNPLTMEAFPRTEADTWLTRVPRAGATWQGVSAHQGATWWSGKSPKKAKGSPRSKATPAGRRPAHVDLESDADPSPIRRPEPEAPPRPRPPATVDLSAFRNFAVPRSRGLGLNQPSSNPSQAGSLDPTEFGADRVRTNGSPDRNRKAVYEGDVGFGHFREESGMVGFDGNEPPDVSMEESEEFWGTQLEPRQQSRQQESEPVSSRPVLLDLPRNPFKRRADEPASGTGWVRQLTTIAPKPRKPLSSKPPRYLNPFAVRTRVAEEGARFQEQKVSPFFAKPASPPSKPPSDPLSRASFNPPSNPPSNPHLTSRAKPAANFPRSVVSARDVGAGEPVCRVPEGQAMSPFQTKRPRKMGAGPIADFSKSPKPVPAKKRLLDDECPLGGEAPSTEERNAAGERRNQRSEGSAAPSESLTKPSDCAVGDGSEELGRLDSKPSEGDERGPPEHPAEGPLKDPQSCPVSSAPQNPLADSSEADQQWNGSEDRQDSHRDVPAPPAPVPAASSPETSVPFFGPSLDSNPEFRSDCGSQEAVLSTPSEELEPAEPFNVPEEALARGLGENSLEGLQSTWAATAASQAAADAGRERTVMSDQGFAHVHRMSASGVNGVRRERGATESAGAAEPVCGAAAGQAFVESNSGSVLDEDCVAMEEEVRPGSEAVLGTREIWGAANVVQENERTELRARGQLQKCPVDDRVDGQKDAAAVDQVEQFETNGQVGKESVDFKRVEASAQSRKVDEGTVLNGLIDLESVELRGPSSLVRLSRPMVPRRQTVKPSSILNFFKPVKVPEGGEERPGKRSIVESRGTNRKLGPSVRKKHKR
The following text describes a protein:
Function:
Catalytic component of a chromatin remodeling complex.
Subcellular Localization:
Nucleus.
Sequence:
MNEIKSESLLQTRPFKLGIEDIQNLGSSYFIENNEKLKKYNNEISSLKKELDILNEKMGKCTTTTKIVEPAKTPEFTFWYYELKEMKGFQDLVMYEVKKKKKHFKVLSHSCLKYLSNREKMKIKKQEEEEKRLKLYSKNISSYMDVFWKKIEKLVWEEKKRELQQTLNKKKEMRFKKFVKEAIKKIKDARHNNAHELFENKYVSMSSNNNSEIVNNNASSVDNGDKELKEDDLTDQEEEDYLLDEQMSSTDESENKEEEINMLDDEANLPIEELLKRMYGFKSGEDYINFMENEDDANEENVIETSHNDEKSGDNSIGEDDNNNDEKGGDNNIDEDDNNNDEKSGDNSIGEDDNNNDHKSGDNNIDEDDNNNDHKSEDNSIGEDDNNNDEKGGDNNIDENDNNSDHKSEDNNIDENDNNSDHQSDQEQFNHETKDDIIKNSSYEHIDNKNYYNKTGEDYKSDKENYSPTRFHNKLKKEKYDEYDTKLKIEKREEENKNYEKDEHEYESDNYDKEKINKKKELILLKNDIENDSDETSEHIKRDSRSSCQKQNCEKKRRIIKDEYNLRRTKIAKSKPSSDNNNSENDNNNDNNNDNNNDNNDDNNDDNNDDNNDDNNDDNNDDNNDDNNNEHKNDSDDNDDILTCNMDEKHLTKIPPIIKATLRDYQHAGLHWLLYLYKNNINGILADEMGLGKTLQCISLLSYLAYYFNIWGPHLVIVPTSILINWEIELKRFCPCFKILSYYGNQNERYKKRVGWFNKDSFHICISSYSTVVKDHLVFKRKRWKYIILDEAHNIKNFNTKRWNIILSLKRDNCLLITGTPLQNSLEELWSLLHFLMPNIFTSHLDFKEWFSDPLNLAIEKSKIHHSKELIDRLHTVIRPYILRRLKKNVEKEMPNKYEHIIKCKLTRRQQILYDEFINNKNVQNTLNTGNYIGLMNILIQLRKVCNHCDLFTNKYIQTPYYYMLSIRYFVPRFFILFEKNYYADFYLILFLHNEFTSLGGRDVTKETSPSSKSFDLAHILTKHNTNELYDNNHISELYDNNHISELYDNNHISELYDNNHISELYDNPMSHKNYKHNSNGYTYPNDPINNMNNNPSGFTKTSEQFGQIVSHERDNNYHMMDHNNMNNLLSKEMVNSLRNDDNSNNNFYKYSLTSNNNDSQTSIHDNKQCDYNKLCADTFNNINSIGNEEKRSLNVLNEQNNNNSKDNNNNIDNNNNIDNNNNIDNNNNIDNNNNIDNNNNNIDNNNNIDNHHNNNQHCNYNDNWPSDYPTNIINHRNAFLSILKLLNQSNPLNNDNNNNNNNNNGNNNIYNMNRYNSRNSRNSSLSNIFSSNTSKMNSFQLDFLYTNSFINQDALCKNSFFVNINIEDVHSYIYNSIYKEYIPKNILSFSDEFLTELNNNYDILSLYIDPYNRYKSYNEYLYKMKEEGTLTNQQSLGDINNKHIYHKSTSNENTHMKNRKTFIYKYNNMFKVINNDTQYQNIFTDDTNNSYYNSLEHNLWIKRNQIDERKKEEEEEQNKYYNVCMNNLYILRNERIPIFGKNFLDLIKKEFTKDKNIVYNYTNNVPIDYYSSVKEVWVEDICEKDNKKRKCKREKRWYKKIKKTNNPPEDSEVYRENSSDVEKYNCDVEKDNCDDEEKDNCDDEDMNSNLSSNVYGCIDISSQNFIHSRYHNPMMNMSYIIEFLFPNMEQFLKRHEKMIHNFTLINNPSVICKSHDIRINNNLLNYSNDKMNPIILQIKNATRVYHDAFLKQSIIFPLNKDISLGSGKLCALEKLLSKCKREGNKCLLFTQFIKMLDILEIFLNHLNYSFIRLDGSTKVEQRQKIVTKFNNDKSIFIFISSTRSGSIGINLTAANVVIFYDTDWNPSIDKQAMDRCHRIGQTKDVHVFRFVCEYTVEENIWKKQLQKRKLDNICINMGNFNNSNTHSKITDTDPTHNKDWFTNVDTIKEVFINKKNNDDDDDMYKDRLLHEQVENKDKMNVRFEKTLEHVEDKDDIRALNETKKETQNEISQNMQEFTTRNDFQDSYNLTSYCFNFLNENLTDSLKQQIDEMRMKIEIEMMNTGDENMSLSDLSNKSHNSE
The following text describes a protein:
Function:
Tautomerase that converts enol-oxaloacetate, a strong inhibitor of succinate dehydrogenase, to the physiological keto form of oxaloacetate.
Sequence:
MSTASSCQKLFDLGTKIIGVGRNYAAHAKELGNAVPKAPVLFLKPTSSYLKNGGTIEIPHNESSLHHEVELAVVIAKKARDVSESSAMDYVAGYALALDMTARDLQSAAKSAGLPWSLAKGQDTFTPISPILPKTAVPNPDDLELWLKVDEEIRQKGSTKDLIFKLPFLISFISSYMTLFEGDVILTGTPPGVGPVKEGQKITAGITGLVDVEFNVGKRKISGT
The following text describes a protein:
Function:
Odorant coreceptor which complexes with conventional odorant receptors (ORs) to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability (By similarity). Obligate coreceptor of all odorant receptors (By similarity). Orco is a universal and integral part of the functional odorant receptor, involved in the dendritic localization of other olfactory receptors. Can form functional ion channels in the absence of an odor-binding odorant receptor (By similarity). Plays a central role in the perception of olfactory stimuli in ants and is essential for ant social organization. Required for pheromone sensing. Also required for the development and maintenance of odorant receptor neurons (ORNs) and of antennal lobe glomeruli.
Miscellaneous:
MISCELLANEOUS: In contrast to other ant species, C.biroi ants reproduce via parthenogenesis, enabling stable germline modifications from the clonal progeny of injected individuals without laboratory crosses.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MMKMKQQGLVADLLPNIRVMKTFGHFVFNYYNDNSSKYLHKVYCCVNLFMLLLQFGLCAVNLIVESADVDDLTANTITLLFFTHSIVKICYFAIRSKYFYRTWAIWNNPNSHPLFAESNARYHAIALKKMRLLLFLVGGTTMLAAVAWTVLTFFEHPIRKIVDPVTNETEIIELPQLLIRSFYPFDAGKGITHVLVLVYQFYWVLFMLIDANSLDVLFCSWLLFACEQLQHLKQIMKPLMELSATLDTVVPNSSELFKAGSADHLRDGDNPPPPPPPQSDNMLDLDLRNIYSNRQDFTATFRPTAGMTFNGGVGPNGLTKKQEALVRSAIKYWVERHKHIVRLVTAVGDAYGFALLLHMLTTTITLTLLAYQATKVNGINVYAASTIGYILYTFGQVFLFCIFGNRLIEESTSVMEAAYSCHWYDGSEEAKTFVQIVCQQCQKAMSISGAKFFTVSLDLFASVLGAVVTYFMVLVQLK
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). SRP9 together with Srp14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (By similarity). The complex of Srp9 and Srp14 is required for SRP RNA binding (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MVFVKNWDDFEIAVENMYLANPQNCRLTMKYAHSKGHILLKMTDNVKCVQYKAENMPDLRKIEKITSNLVGHMASKE
The following text describes a protein:
Function:
Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MNYPYSSFEDDGQYQTDLSEVASRNADEEAAGHQQQQLQYHRRVQIEEATRQRQQQQQHHQQQSSPSSSDDFNFESQQIKPNRPKNSPPKPIFVDKDGKSMLFYIPEDEPNRNKYRDLIIRYGGVIVEKGFPTVILLSNNEDLYGFSKLKFIDDCIAKNQLLSVFDYGTYGTYNNPEDAAFDTTSIINELNDDLSSNISSSFSTIEGTSSMVEVPVAAPAAIPLPPPPHQQQRSIDAFPNPNINNARRGSSGHRFTIEQDEFILEHIRRKPRFRQSQKFYAQLALLEPLRGHTGNSIRSRFRKHLESRLNYIYKTDDQDQLIRDEAGNLIKIGLDEMPGTLKNKFTPEDDYLLCCVALEYMASNNIDSIGLRYSFFDGMYRKYRNHTLQSWRDRFRKYIRDKSDLVDYKEYYENCEKVGMAPRCLTRIAP
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MAFLRTILGRTTTTSKLLNPLNQQQANQFSIGQQLFVWGQRKKNQVDKNFKIYKPVTPAIRHLRLPRNDHLHKGRCYLPLTLPKKKTGGRNNSGRITTRHIGGGHKQRLRMVDFHRNLSGPQLVVRIEYDPGRSAHIALIKHVQSGALSYILAPLNLRPGQIVQSFKTGIPKDLLNSSNSILDQPTPEANPAGQPSTVASQGVGELISAKEVSNSTLTLGLLRTLTIKPGNYLPIRLIPAGTTIHAISLKPDGKASLVRSAGTFAKVVSLGHHHRKTKASSKQASSVQQQQQQQQQQQSTGAQEQKTDQRDLHDLQDHQGDYAQIKLQSGEIRFVHMDACAAIGSVSNPHWQGRKLGKAGRVRWLGRRPRVRGVAMNKVDHPLGGGRGKSKSNKQPVSPAGLKAKGLRTRRPGPRGNQMVVKQRPKGKHVGK
The following text describes a protein:
Function:
Probable transcription factor, required during migration of the gonadal distal tip cells (DTC). Probably regulates cell adhesion of DTCs via modulation of expression of genes involved in integrin-mediated adhesion, including tln-1, src-1, and integrin pat-2. Modulates expression of genes involved in protein trafficking during embryogenesis, including emo-1, sec-61, calu-1, sec-24.1, enpl-1, sar-1 and tfg-1.
Subcellular Localization:
Nucleus.
Sequence:
MDQDFDLDEGAGQFNLKTTLMMFTSNDSQNDDGIWSPGSPYQALEDPSFLDKHFVSDPDRYTADELYSALEKMDGKSDLIGMDDMDNDNCYSLSPPDSGSLPISPASTSPSSYHSSGGEDLMDCYPSIDILQQASEELLYSKDDDYEICSSGPLLAYTNANSVATSAVHQNQQQQQRRLNQAGFPHQNSNGLVRFKSSQPRVLNPASISLNAPSSSFNPQSTSSTPATSSSSSSSTNGGFVKSSTGERRKYPPLRLDEEEIKLCKKEGICLPDFFPLTKAEERDLKRIRRKIRNKRSAQTSRKRKQDYIEQLEDRVSESTKENQALKQQIERLSSENQSVISQLKKLQAQLGQNAKRTTQAGRCLAVFMLSACLLVSPQLSPLGNQDNQKVLECIEEACQPSATSMNSANSAQRAIAGVTAPSVVIPSGGPVMVSTNANRQMNRNAVLNHHNNSKYPASGNQNHHPIALEDLNHPPPTLQPKQSYQQQHQPSMYRRSDETIAMAMAKIGARKGSSTSSSSASSVASSTSTSSATSPIYRTSRTLGAFEDQCDASSDDSNCANMPSLVPMKMSAQPPKRKIVTMNGQPRVTYRAVPASSVNVEQAQYYKVPQQKVQYVTMDRPIKYEVLQLNDYIKMEEESTIRLPNSWSTAGPRLHPQVNASSRTVRPLTVATPVHYNGPSAKKIKTQMF
The following text describes a protein:
Function:
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MLLEVLQAAEAGGFILIQDSVQCCGRGILRCCINAALKRDEDVHVLGFESPETEVCAGLDSSFAQKLHFHKGFPDPLGWRGKSSFTVQQFTSQHITQLIRDSQPAKASVLVVDSLSLVLRHHDPVIVCQSLQELRKGGVVKTIIGLLHSDLHLQGIVGIVCHLASTVISVAPTNNERHAVATTTRRTKSGKVMQEEEYFSVSEDATLSVQSKPRQHDRVEKEQDSAEVDPASNLTFNLRLSEEERRAKEKVALPFVFSQEKKSALLRPTPGSGRIMYEPDANDDFDEEDPDDDLDV
The following text describes a protein:
Function:
Involved in the assembly of the cytochrome c oxidase complex.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MSRLHEASQPLIGDGSERANASDVSGTKVQATKLRAAISSIDPVNDISRIGSIPCARASLLIGMATAAGVAGISLVAGRGLRRGLNWGVGSFCFVSLASWEMCRRNLKAEQMRIKTVIESYKKSSRAGQPSVTERASLEKQHQET
The following text describes a protein:
Function:
Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.
Sequence:
MDAQSTKDQGPEGADAGTLSFTYHIGDMFEDAPENCLLIHACNSQGHWGAGIAKAFKQKYPKAYTAHNKFCAKEHSKTQPVPTGSAQLLAPVDSGSQHWIGCLFTSAKYGKAKDKPDAIVKNTTASMSMLLELVRMADGEVSEIRMCKINSGKFGVPWEKTEEALKSIILQEGWREKIEIWEP
The following text describes a protein:
Function:
Probable glycosyltransferase that may be involved in the biosynthesis of xyloglucan.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MRGLKLHKACITDFEIPLPNPHAIHVAADTDEPGSDVTRDLHHLQCSFNLQTRKLATQGAAAPSVPSSTMTEQPVAADRRARQHRPPQLLVLPVFFLFLVAPCALFLFRSSDLALIPRIRIEFDRREALSIAPTNVPTPAQPVPLPSPPPPSPAPPPPGPAADDDEERRRLPPPRQLTDPPYSLGPTVDYDARRAQWLRDNPRFPAFVAPGRPRVLVVTGSSPRRCSDPDGEHLLLRAFKNKADYCRVHGFDIFYSTAVLDAELSGFWSKLPLLRTLMLAHPETELLWWVDSDVIFTDMLFEPPWDKYAAHNLVLPGSEEKVYTVKSWIGINAGSFIIRNCQWSLDLLDALARIGPRGPVREMYGRVISETLSDRQPYEACDQSALVYLLITERGRWGDKTFLESSYCLSGFWAYIVDKFEEMRRDSTTPPEPGRERWPLTTHFMGCKPCGGKDSTYDAAWCRRSMERALNFGDDQILNLYGFQHKSLNTTAVRRVRNDTGGPLDTGDEELGRLLHPTFRAANL