lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Functions as a two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Domain:
Histidine-containing phosphotransfer domain (HPt) contains an active histidine that mediates the phosphotransfer.
Sequence:
MSILDLKARLRAHIQSLFDEGILDSLQFAELQSLQELSDPAFVANTLATFLNDSQRALAEMSKILDRPIVDYQRLKVYVMQVKGSSLSIGARLLVLACTEFIRVSSGHFKDGCIRALNRMKNEHYHLQCQLETIIQVYQPASSVESCSQSETGQDRALFSSTTPSSPIFAEAQALLAGIKLARSSNVKNLQNLRIFSDNSNLVQATSSNFSLKK
The following text describes a protein:
Function:
Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor/signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKKNIISIIIVCLSFLTSIILYQYLPEEIPIQWSGNKPAAIVSKPLTIFIIPVVMLIYYLTFYMLTIKSTQKNKALLFLASNNMLILLYILQLSTLLISLGYEVNIDLIIGLGVGIFLIIGGNSMQLAEQNHLIGLRTPWTLKDETVWKLGNRFASKVLVVCGFIIAVLSFFTGEYIILIMIVLVLLALVISTLASYHYYKKLNGSR
The following text describes a protein:
Function:
May be involved in the initiation of hepatocyte growth.
Sequence:
MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAPQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFNQDLGFRMLNCGRTDLISQPSSPGPDGVNTMDDQGLTPLMYACATGDEAMVQMLIDAGANLDIQVPSNSPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDTSSQGSSEGPVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQGLLRDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDNSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQMPSGSSSMAEAAKSRAWTHCRICRAP
The following text describes a protein:
Function:
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II.
Sequence:
MASAPSHSSQKRPLPAEPNPVLHASQTQWLFTDEELTRTPSQLDGMKMEAEHTSRSKGVNFITQVGIMLKLPQLTLATAAVYLHRFFMRYSMVDIPQRPGMHPYPIAATALFLATKVEENVRRMRELVVACCRVAQKQPNLVVDEQSKEFWKWRDTILHHEDLLLEALCFDLQLEQPYRILYDFICFFGVNDNKPLRNAAWAFVNDSMFTVLCLQFTARTIAAAALYAAARHCDVGFPDDDRGRAWWEQIDVDLTQVRRACMRMAQLYENNAMQKHSQYYPTTPILSDEGTEKTRIPHAGSPANLPPAESDVTHGRKRSKEPEDSGEPRGDGSAPSNGERSPKRPRRDADAAPRGSWQDQQSPSAPSSQSLPNAGSPSSSSQGRPHLNGQAPPSLPHPPVHHRHPHPLPPAPRPFPRRDSDHHPPGGGKVAGPREADPIQQRIDEIVSQNMPSHGAPPVPPPSGAGARIPNRRNSVDRRGPDRYRGYEDPARRRRSSFGRRSQSFEEQPPPLPGHPHHQPLPPPPPPPDIPQPPPPPPPSQTQQAAQEDEGGGSEEGEL
The following text describes a protein:
Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence:
MDPNCDCVSGKDSWVPLTLIISCLSFSGCCSCCPAGCAKCAQGCVCKAPQTESCSCCH
The following text describes a protein:
Function:
With TAX4, acts as a positive regulator of INP51 activity and phosphatidylinositol 4,5-bisphosphate turnover. Negatively regulates signaling through the cell integrity pathway, including the MAP kinase SLT2. Also seems to be involved in rDNA silencing.
Sequence:
MRLSFGKQRYHGGTTVTLTEQGASDSLRAAQAIFQNHSNEVSSPCPPVTVSRNPQTRLSEPSLQKSGRKQEQKKARIRTKQVPKIKTTAPNDVELSKKHRSSPAGKDNVSSTAQMAAALAHSQSKLSSDNNSSHSSALDTLKVLETPNLNGLLGIHSRSSSRNGSNESLTPGQRTPDNRSQENLLTSFSSGRRLSSSSMEPATNKDSNKALPKRRPSPPLQSSLVGSGQLHENENLSSISIDSRHSLNPDTSDVISNRSQTSLSQTINQLSLCESEPSIASSNTTTTTSNQGSGLPNLVPNYSSDMRKKKLVNKFKRKVFGSKPKHLSSQYEMDASSEELGQHEQQPSMRFKTTLRKTSVSTNAENDHASSLHEGNLRYKYNPSNDTYDVYDDTDSDSESDQNQDALTKPRKRDRIKRKIRNSANKTAHHRPIHRTRDRKFNEDKPWKSHTDITFVTDNERKRYESMWVSNRHRHLNLLSWWPSITGDSGAINTLPEDGLILGIIVRDIWKRSNLPNSLLAEIYTKVDTRKDGTLDRKSFIVGMWLVDQCLYGRKLPNVVEQCVWDSVDRYASTTVVPVSTLKAMAKQKRKQMKEEIKNIKKENRVVLVDHNSSS
The following text describes a protein:
Function:
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MASDSFFTKLNEALRKIPPVTRYTVLCMTGVTILILCEQLSAGLLYFEPKLVYKQIQVWRIFTTFLYAGTGFPFLMTVFAFYQYSSSLENVLFAGKSKAYLIYLVHLCAAICLCASIFSNGFYMCNALLLAITYRWSLVFPDRIVQLLFGIQMQSRYLPYVMLLFSFLSRGPSGLLIDLYGIAAVYASKPLERMYAPQPFRYSNPARPSTSGSTTQSPPSFTQNRFQGRGRKLGN
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Parts of the peripheral arm of the enzyme, where the electrons from NADH are accepted by flavin mononucleotide (FMN) and then passed along a chain of iron-sulfur clusters by electron tunnelling to the final acceptor ubiquinone. Contains one iron-sulfur cluster.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MFQAFSAAPRARAAGLTAHWFWAQESPGHVRNLHKTAMQNGAGGALFVHRDTPENNPDTPFDFTPENYKRIEAINGWLPISAMNKVAEVLQVPPMRVYEVATFYTMYNRKPVGKYHIRVCTTTPCKLRNSDSILEAIQKKLGIKLGETTPDKLFTLIEVECLGACVNAPMVQINDSYYEDLTAKDIEEIIDELKAGKIPKPGPRSGRFSGEPAGGLTSLTEPPKGPGFGIQAGL
The following text describes a protein:
Function:
May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. Involved in regulation of MAPK and Akt signaling pathways (By similarity).
Subcellular Localization:
Apical cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Endoplasmic reticulum. Endoplasmic reticulum-Golgi intermediate compartment.
Sequence:
MLWKTALIFLCWGLTSGELQNGLSATPAAPARRTLDFGFVPSGVYDTVAYYEPGAIGILFNMMHAFLFVVQPNPFPEDLVISAAKDKFGAIQSEYQKVIYYELGFVVCAALGLLFTVLLPLVGLLFCLCRCCDNCGGEMHQRQRKNADCLRGLLTTLLLTTTFIITAGVLCAYAANQNLSSQLKGMRRLVKSNLKDLHTFANQTPAQIDYLISRYGTVKEQVLHDLENVGVILGGRIHEELGKEVKPALDATLSMTGTMRDTKDALENVSLTLETLQEGTVKLQANLSVVRNSLRNALNDPVCVDAPAPEICRNIRNSIPKLEIAANYSSLPDVTDQLNKVNDVLKTDLSQIVAKGIASFNDTPAMVTAQTRNIVEGVKVLLDDIGNNITSFSKMLPVHSSLANFTRMISHTHSQIEDIYPQIDQMDFYRWIGCITLCCMIVLILTFNFLGLLCGILGFDRHASPTTRGCVSNTGGNFLMAGVGFSFLFSWVLMGVITALFLAGGNLEKLVCEPFQTRQLFKVLDTPYLVNSAWRNFIPGYLYNDPEMDLTAYSLYSNCKDNRGIYSALHLDRIFNISSFFNTSVYSKDVSRKFEGLKVDLRGIILLESEGKVNLNNFSETGINEIDFAAYLEEVNKGVTRIDLIDFANQLDAQADQLSKGTLQTSLKGHANTIRQIHIQQVVPLEQSMSTLNQSIRLLERTSSDLPLRVEDVLKAVDDAQNLISYNATFVINQETEKYKQNIIGYFKQYIDWIRTSLALEVATCKPLSNIVDTVEILGCGFLLDSMNTFWFGLGCCTLFLLPSIILSVKLAKFYRRMDTEDVYDE
The following text describes a protein:
Function:
May be involved in plant development processes.
Sequence:
MEQYEILEQIGKGSFGSALLVRHKHEKKKYVLKKIRLARQTDRVRRSAHQEMDLISKVKCPFIVEYKDSWVERGCYVCIIIGYCEGGDMAEAIKRANGVQFSEERLCTWLVQLLMALDYLHVNHILHRDVKCSNIFLTKNQDIRLGDFGLAKMLTSDDLASSVVGTPSYMCPELLADIPYGSKSDIWSLGCCLYEMTAHKPAFKAFDIRALINKINKSMVAPLPTMYSSAFRGLIKSMLRKNPELRPSASELLTLPHLQPYVLKIHLKSSSPRCDNFPTRWSDSSFMKKTKFVEKDSTRFSDIGRRRSFSNDRALNPSVSETEQDSLSGIRRVQEIPSSLFEKFTAISVGIDNEDITADKSTATKFSTVAKTPRLTPAVSVTPRKHIIPSKISKTGQKHDLVPVSQTPSSKSSYSSRRVSLPLPSRTAAIVTPYRANVVSLPTSNSPDVSVNAPRIDKIAEFPLASSNDPVLPIRQTSSTSAKCSSSSSIDSADRSITKDKCTVQILEKAVATSNVSDQSLGVAQDGSEGGSEHNRAAVSIRSSSESRQRRFDTSSYQQRAEALEGLLEFSARLLKQQRYDELGVLLKPFGPEKVSPRETAIWLAKSFKETQV
The following text describes a protein:
Function:
Gap class segmentation protein that controls development of head structures.
Subcellular Localization:
Nucleus.
Sequence:
MQNWETTATTNYEQHNAWYNSMFAANIKQEPGHHLDGNSVASSPRQSPIPSTNHLEQFLKQQQQQLQQQPMDTLCAMTPSPSQNDQNSLQHYDANLQQQLLQQQQYQQHFQAAQQQHHHHHHLMGGFNPLTPPGLPNPMQHFYGGNLRPSPQPTPTSASTIAPVAVATGSSEKLQALTPPMDVTPPKSPAKSSQSNIEPEKEHDQMSNSSEDMKYMAESEDDDTNIRMPIYNSHGKMKNYKCKTCGVVAITKVDFWAHTRTHMKPDKILQCPKCPFVTEFKHHLEYHIRKHKNQKPFQCDKCSYTCVNKSMLNSHRKSHSSVYQYRCADCDYATKYCHSFKLHLRKYGHKPGMVLDEDGTPNPSLVIDVYGTRRGPKSKNGGPIASGGSGSGSRKSNVAAVAPQQQQSQPAQPVATSQLSAALQGFPLVQGNSAPPAASPVLPLPASPAKSVASVEQTPSLPSPANLLPPLASLLQQNRNMAFFPYWNLNLQMLAAQQQAAVLAQLSPRMREQLQQQNQQQSDNEEEEQDDEYERKSVDSAMDLSQGTPVKEDEQQQQPQQPLAMNLKVEEEATPLMSSSNASRRKGRVLKLDTLLQLRSEAMTSPEQLKVPSTPMPTASSPIAGRKPMPEEHCSGTSSADESMETAHVPQANTSASSTASSSGNSSNASSNSNGNSSSNSSSNGTTSAVAAPPSGTPAAAGAIYECKYCDIFFKDAVLYTIHMGYHSCDDVFKCNMCGEKCDGPVGLFVHMARNAHS
The following text describes a protein:
Function:
Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
Sequence:
MSATPQVSDASFKEDVLDSELPVLVDFWAPWCGPCRMVAPVVDEISQQYEGKVKVVKLNTDENPNTASQYGIRSIPTLMIFKGGQRVDMVVGAVPKTTLASTLEKYL
The following text describes a protein:
Function:
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Secreted.
Sequence:
MRARLSARQPRRLGGWEPERWPRSQQPGALGERRVGGVPAPRTPARPAGPARLAASMGAAAVRWHLCVLLALGARGRLAGGSGLPGPVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGRQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYALHSDGRTCIEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCRDTATGVRCSCPVGFTLQPDGKTCKDINECLTNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYTLYGTTHCGDVDECSMNNGSCDQGCINTRGSYECVCPPGRRLHWNQKDCVEMGKCLSRAKASPWAQLSCSKVGGVESCSLSCPAHSLFVPDSENSYSLSCGVPGLQGKMLQKRNSTSSSTGPSCSGVPAPIRQKARFKIRDAKCHLRPHSREPAKEALRQLLLENCHLTFVTLKCDSSKKRRRGRKSPSKEVTHITAEFEVEIKMEEASDTCEADCMRKRAEQSLQAAIKTLRKSIGRQHFSIQVAGTEYAMAQWPAKALEGQGACSTGQVLQDGKCVACGPGTHFSGEPGQCVPCVPGTYQDRDSQLSCTPCPSSDGLGLTGARNVSECGGQCSPGFFSQDGFRPCQACPVGTYQPEPGRTGCFSCGGGLLTKHEGTVSFQDCETKVHCSPGHHYNTTTHRCIRCPIGTYQPEFGQNHCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHISPPPKRRILIVVPEIFLPVEDECGDVLVMRKSASPASITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKVSDLLYGKGSRVIPGWWPVVVRAIPVPTPTPSPQRRERRRGAGPGSRASVLADQEG
The following text describes a protein:
Function:
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for proper rRNA processing and maturation of 18S rRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MPLIEVDLLNPTAASEAKAHKMKRLVPTPNSYFLEIKCPKCGATTTTFSHAHRQILCQKCGQPLGQPTGGKLKLTQQCKFRIKK
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MERDFMGLICKDSVVAVKEEFVDGDCQDSAGFARNSSAPWQFPNKVPSQLDEPSKNGHSPQPIHDFKNMHTSSMMSSPFFKTRFMGAQQFLGANTPTPPRSILPPSGTTEQWTNSKASTIPPPKLTIFYNGTVNVFDDITPEKAQAIMFLAGNGFMSTNMGQSKHHMQAPVAKLPAGDRPSVSQSMNMPPSPMSISSHPVDVNNDEAKVTAATSATLVNKVETPRVMSSLGSVSASAMISSAVPQARKASLARFLEKRKERAMSAAPYNVSKKAGDCATPESNGFGFSATSGNCAL
The following text describes a protein:
Function:
Binds to specific AU-rich elements (ARE) in the 3'-untranslated region of target mRNAs and promotes their degradation. Binds to ARE present in the arz1 mRNA and stimulates the rate of arz1 mRNA decay. Required for coordination of septum formation with exit from mitosis. Involved in the mating response pathway. Induces sexual development and ascus formation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MVYSPMSRPQVPLAFRQWPPYNYKSDPLVNSKLSQSTTSVNAGPSLISPSFLDSYANSSSLLHKPSTNLGSLKTSSLLASDEVFPSSVMPQLRPLDSSLSVSPEMDGWPWHHNSSSNPQGYAWTPSLLSSNATSYLHSGSSPHGNTSNHPSPISSLESLPSRSSTGSGSLDFSGLANLHDDSKSLAMSLNMAGVPVSVDENSQTSFPFVHGQPESTMSRKPKLCVQSKSMTNIRNSVAKPSLVRQSHSAGVIPIKPTASNASIRNAPSNLSKQFSPSGNSPLTEASKPFVPQPSAAGDFRQAKGSASHPHGSGSSNGVAPNGKRALYKTEPCKNWQISGTCRYGSKCQFAHGNQELKEPPRHPKYKSERCRSFMMYGYCPYGLRCCFLHDESNAQKSATIKQSP
The following text describes a protein:
Function:
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
Sequence:
MHNTLILFGATGDLAQRYLFPSLLRLFVDGLLPEDFRIRALALSQHDTDAFREVLRPRLAQALPIATAAQIDALLQRIDYRSADLRNAESVAEAVRELASRQCVSYLAIPPGLYISTCQGLALGGALAAPHRLMLEKPIGHDSDSAREILQSIGALIDEDRVFRLDHYLGKAAVQNLVALRFGNTLLEAVWNRTYIESVQILVAESEGVDGRDAYYARSGALRDMVQSHILQLLCLVAMEPPASLEADRIRDEKVKVLRALRPMTAEHAAQDSVRGRYTAGSINGEPAQAYHPPEGSDVETFVAVTAHIDNWRWAGVPFHLCTGKRLAERSTRIVVTLKPVTHWLFERPDRQNAVPNRLTFQLQPLENIELGLMSSLAGPEWGAIELQPLELELSVPTGLHRRIAYERLFVDAFNGNPALFVRDDEVKAAWAWIDSVSDAWSDAQLPLQPYPAGSWGPETAAPFLPPATDAQGNNA
The following text describes a protein:
Function:
Filament-forming cytoskeletal GTPase.
Subcellular Localization:
Cytoplasm.
Sequence:
MDSLVLQERLAERLLSPRAQAQRRLPRLKDHEKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVTSLFLTDLYKDRKLLNAEERINQTVEIVKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWRPVTDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVEFMKALHEKVNIVPLIAKADCLVPSEIRKLKERVREEIDKFGIKVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMASKLTQDNRIESPIPLLPLPTPDAETEKLIKMKDEELRRMQEMLQKMKQQMQDQ
The following text describes a protein:
Function:
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
Sequence:
MSFNNKEILISYSDQYRDDYYNYMIVYLDQKISEKIPIDKRGFLLREPEWRELGIKLFKGWLNYDVHYPDPYILFFRKRVDPRIQERKIQQAQ
The following text describes a protein:
Function:
Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.
Sequence:
MKAPSRHPAVPSWGQMIRMTEPSKITSVPDHQPAAGGIAARARASVGPKYLSGLNPEQREAVETLDGPVLVLAGAGTGKTRVLTTRIAHILSQGRARPAEILSVTFTNKAAREMKHRLGQMLGHAVEGMPWLGTFHSIGGRILRTHAELAQLKSNFTVLDVDDQVRLLKQLLQAENIDDKRWPARMLAGLIDGWKNRGLTPSQVPSGEAAVFANGKGGKLYTSYQERLKILNAADFGDLLLENIRIFREHPDILRQYQQRFKYILVDEYQDTNVAQYLWLRLLSQAPSPKVVIPGRVEDANPESRDSGFDAPHRPGMTEQTAGTPTATPHVKNICCVGDDDQSIYGWRGAEVDNILRFEHDFPGAKVIRLERNYRSTGHILAAASHLIAHNEGRLGKTLRTEDQDGEKVTVTGSWDSEEEARGIGEEIEQIQRQGEKLNEIAILVRASYQMREFEDRFVTLGLPYRVIGGPRFYERAEIRDALAYLRVINSPADDLAFERIVNTPKRGLGDATVQMLHDHARKRRIPLFEAARAVVETDELKPKARGSLRDLVAQFDRWRAQREVTAHTDLAQIVLDESGYTEMWQKDRSADAAGRLENLKELVRSMEEFENLQGFLEHISLVMDRDGGAEEDAVSLMTLHSAKGLEFDNVFLPGWEEGLFPSQRTLDEQGRAGLEEERRLGHVGITRARRRAMIYFATNRRIHGTWTTTIPSRFLDELPAANVEITESKGGSAWGGTGGYGASRFDDMEAFGSSYTTPGWQRAQANRNRGGGRTGAGGHGSFEEEAATFSSSSSSGPDFGSFSSRRRGPMTIEGELVAKSTGTTSEFSLSDRVFHQKFGYGRVTKIDGNKLTIAFDKAGEKKVVDSFVQRA
The following text describes a protein:
Function:
Beta subunit of the SNF1 kinase complex, which is required for transcriptional, metabolic, and developmental adaptations in response to glucose limitation. Has a structural role, mediating heterotrimer formation, and a regulatory role, defining carbon source-regulated subcellular location and substrate specificity of the SNF1 kinase complex. Promotes the PKA-regulated relocalization of the SNF1 kinase complex to the vacuolar membrane in response to various types of carbon stress.
Miscellaneous:
MISCELLANEOUS: Present with 623 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Vacuole membrane; Peripheral membrane protein; Cytoplasmic side. Note=Resides in the cytosol during growth in glucose and relocalizes to the vacuolar membrane in response to carbon stress.
Sequence:
MGNSPSTQDPSHSTKKEHGHHFHDAFNKDRQGSITSQLFNNRKSTHKRRASHTSEHNGAIPPRMQLLASHDPSTDCDGRMSSDTTIDKGPSHLFKKDYSLSSAADVNDTTLANLTLSDDHDVGAPEEQVKSPSFLSPGPSMATVKRTKSDLDDLSTLNYTMVDETTENERNDKPHHERHRSSIIALKKNLLESSATASPSPTRSSSVHSASLPALTKTDSIDIPVRQPYSKKPSIHAYQYQYLNNDETFSENSQMDKEGNSDSVDAEAGVLQSEDMVLNQSLLQNALKKDMQRLSRVNSSNSMYTAERISHANNNGNIENNTRNKGNAGGSNDDFTAPISATAKMMMKLYGDKTLMERDLNKHHNKTKKAQNKKIRSVSNSRRSSFASLHSLQSRKSILTNGLNLQPLHPLHPIINDNESQYSAPQHREISHHSNSMSSMSSISSTNSTENTLVVLKWKDDGTVAATTEVFIVSTDIASALKEQRELTLDENASLDSEKQLNPRIRMVYDDVHKEWFVPDLFLPAGIYRLQFSINGILTHSNFLPTATDSEGNFVNWFEVLPGYHTIEPFRNEADIDSQVEPTLDEELPKRPELKRFPSSSRKSSYYSAKGVERPSTPFSDYRGLSRSSSINMRDSFVRLKASSLDLMAEVKPERLVYSNEIPNLFNIGDGSTISVKGDSDDVHPQEPPSFTHRVVDCNQDDLFATLQQGGNIDAETAEAVFLSRYPVPDLPIYLNSSYLNRILNQSNQNSESHERDEGAINHIIPHVNLNHLLTSSIRDEIISVACTTRYEGKFITQVVYAPCYYKTQKSQISN
The following text describes a protein:
Function:
May play a role in vesicle trafficking.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side.
Sequence:
MTGVGENQLISIQPDELKFLFELEKQSYCDLKVANKTENYVAFKVKTTSPKKYFVRPNTGVIQPWDSCIIRVTLQAQREYPPDMQCKDKFLLQSTIVPPHTDVDELPQDTFTKDSGKTLTECKLKVSYITPSTTQRSSESGATNGDGQSSETISTIQRLKEERDAAVKQTQQLQHELETVRRRRNQRNSGNGLSLKLAAMVGLIGLIIGFILKLTLASPT
The following text describes a protein:
Function:
Component of an E3 ubiquitin-protein ligase that includes cul4 (By similarity). Required for ubiquitination and the subsequent degradation of the DNA replication licensing factor cdt1 and of the ribonucleotide reductase inhibitor spd1. Also required for transcription-coupled nucleotide excision repair.
Subcellular Localization:
Nucleus.
Sequence:
MTYVTYLHKPSSIRNAVFCKFVNASSWNVIVAKVNCLEVYSYENNRLCLITSANIFAKIVNVKAFKPVSSPTDHIIVATDSFRYFTLFWDANDNTVSNGIKIQDCSERSLRESQSGPLLLVDPFQRVICLHVYQGLLTIIPIFKSKKRFMTSHNNPSLHDNFSVRIQELNVVDIAMLYNSSRPSLAVLYKDSKSIVHLSTYKINVREQEIDEDDVVCHDIEEGKLIPSENGGVFVFGEMYVYYISKDIQVSKLLLTYPITAFSPSISNDPETGLDSSIYIVADESGMLYKFKALFTDETVSMELEKLGESSIASCLIALPDNHLFVGSHFNNSVLLQLPSITKNNHKLEILQNFVNIAPISDFIIDDDQTGSSIITCSGAYKDGTLRIIRNSINIENVALIEMEGIKDFFSVSFRANYDNYIFLSLICETRAIIVSPEGVFSANHDLSCEESTIFVSTIYGNSQILQITTKEIRLFDGKKLHSWISPMSITCGSSFADNVCVAVAGGLILFFEGITEVGRYQCDTEVSSLCFTEENVVYVGLWSADIIMLTYCQDGISLTHSLKLTDIPRSIVYSQKYGDDGGTLYVSTNNGYVLMFNFQNGQVIEHSLRRNQLGVAPIILKHFDSKEKNAIFALGEKPQLMYYESDKLVITPLSCTEMLNISSYVNPSLGVNMLYCTNSYISLAKMSEIRSLNVQTVSVKGFPRRICSNSLFYFVLCMQLEESIGTQEQRLLSFLRVYEKNTLSEIAHHKFNEYEMVESIILMNDDKRVVVGTGFNFPDQDAPDSGRLMVFEMTSDNNIEMQAEHKVQGSVNTLVLYKHLIVAGINASVCIFEYEHGTMHVRNSIRTPTYTIDISVNQDEIIAADLMKSITVLQFIDDQLIEVARDYHPLWATSVEILSERKYFVTEADGNAVILLRDNVSPQLSDRKKLRWYKKFYLGELINKTRHCTFIEPQDKSLVTPQLLCATVDGSLMIVGDAGMSNTPLLLQLQDNIRKVIPSFGGLSHKEWKEYRGENETSPSDLIDGSLIESILGLREPILNEIVNGGHEGTKLDISVQDLKSIIENLEKLHP
The following text describes a protein:
Function:
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Cleaves muropeptides, but not peptidoglycan.
Subcellular Localization:
Cell membrane; Lipid-anchor. Secreted, cell wall. Note=Detected in the culture supernatant, predominantly associated with cell wall-derived particulate material. A minor proportion is detected in the soluble fraction.
Sequence:
MRPVFPLILSAVLFLSCFFGARQTEASASKRAIDANQIVNRMSLDEKLGQMLMPDFRNWQKEGESSPQALTKMNDEVASLVKKYQFGGIILFAENVKTTKQTVQLTDDYQKASPKIPLMLSIDQEGGIVTRLGEGTNFPGNMALGAARSRINAYQTGSIIGKELSALGINTDFSPVVDINNNPDNPVIGVRSFSSNRELTSRLGLYTMKGLQRQDIASALKHFPGHGDTDVDSHYGLPLVSHGQERLREVELYPFQKAIDAGADMVMTAHVQFPAFDDTTYKSKLDGSDILVPATLSKKVMTGLLRQEMGFNGVIVTDALNMKAIADHFGQEEAVVMAVKAGVDIALMPASVTSLKEEQKFARVIQALKEAVKNGDIPEQQINNSVERIISLKIKRGMYPARNSDSTKEKIAKAKKIVGSKQHLKAEKKLAEKAVTVLKNEQHTLPFKPKKGSRILIVAPYEEQTASIEQTIHDLIKRKKIKPVSLSKMNFASQVFKTEHEKQVKEADYIITGSYVVKNDPVVNDGVIDDTISDSSKWATVFPRAVMKAALQHNKPFVLMSLRNPYDAANFEEAKALIAVYGFKGYANGRYLQPNIPAGVMAIFGQAKPKGTLPVDIPSVTKPGNTLYPLGYGLNIKTGRPL
The following text describes a protein:
Function:
MFS antiporter that does not display functional linkage as drug transporter and performs functions that significantly affect biofilm development and virulence. No substrate for transport has been identified yet, but plays an important role in the growth in the host.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=In contrast to QDR1 and QDR2, does not accumulate in membrane rafts and shows uniform distribution at the cell membrane.
Sequence:
MSHSPNLSPQISNDIIDADTTSLASTETQQNIQHSQIHPIGHHGREQSEEPQNTTKTTTTTTNKIHTTTPSVDPDLGPLRELEQDLSSLESQQEQYLSQKPTSTSIKTNKVPLRERRGLLAQIVLIPEYEDARDYPNKIKYLIVFIIAFASLAGPFGTSVMLPAIDDIVNDLNTNVSTVNVSVGIYLLSLGIFPLWWSSFSERFGRRSVYMVSFTLFVAFSIGTALSPNIAALIVLRVLQGGSSASVQAVGAGTIADLFIPQERGQAMGLYYLGPLAGPFLAPILGGAVSQAWGWRATQWLLMIISACSFVLITFFLPETLRRVDTIQVAKDLMKKSDNNGSQNEKIHDDFAGADNSSVHDIDGNPIPGTELHQVVSNLSRRSSNARSIVTYMEEQENEGPIIDPVMPSISRLTTNRSAYSQRIHQNYVTDELRKTTSNLTQSNHSQYNNNNNNDNDKWSSVKTNCYDLIIRPLHSIILLKHPPVVLVISFSAISFAAIYFFNMAISYEYARSPYNFSSVILGLMYIPNSVTYFMASIIGGKWNDRLLNRYAQKHGELVPESRLSWNIVVAIILYPMACLIFGWTIKYREFWVIPLIGTALFGFASMLVIGATVTYLVDSLPGKGATGVALNNLIRQILAAIATFIVEPLLRAIGAGVLFSIIAGILLVSSLVLLYLKKRGAFFREHYDVMDLYAKL
The following text describes a protein:
Function:
Involved in biosynthesis of fatty acids in mitochondria.
Miscellaneous:
MISCELLANEOUS: Present with 1760 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET
The following text describes a protein:
Function:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Sequence:
MEEVPQDSRLAIAQKVFLIQTKDVPDVKRDELKEEVLAAIYKDNLAPLYQYLCTELGWPLDSARLTAMQEVNAGKVAELELKRKDAEENLGETEVRDAMLAKAEFLGSVCDREAAGKAYDEVEKKTASGGNRVDLLLSQIRLAILYKDWRAVKALVARAQALCEEGGDWERKNKLKVYQGMLALYSRQFAAAADLLLDSTATFTASELFPYSRLIFYAVVAALPTLSRTELKKRVVDSPEVLSVIHSLPGVQSLLEALYSCKYRQFYSSFLEVVAEMGRDMFLRHHIRHYSRELRAVFYTQFLESYKSVTLESMATAFDVSPAFLDGELVDFIVAGRLHAKIDKVSGVIETNRPDAKNALYADTLKKGDLLLNRVQKLARVIDME
The following text describes a protein:
Function:
Ligand of InR/insulin-like receptor.
Subcellular Localization:
Secreted.
Sequence:
MMFRSVIPVLLFLIPLLLSAQAANSLRACGPALMDMLRVACPNGFNSMFAKRGTLGLFDYEDHLADLDSSESHHMNSLSSIRRDFRGVVDSCCRKSCSFSTLRAYCDS
The following text describes a protein:
Function:
Component of a multiprotein complex required for the assembly of the RNA endonuclease module of the integrator complex. Associates with INTS9 and INTS11 in the cytoplasm, stabilizing the INTS9-INTS11 heterodimer and blocking the active site of INTS11. BRAT1 then joins the complex and plugs the active site of INTS11, leading to WDR73 release and nuclear import of INTS9 and INTS11.
Subcellular Localization:
Cleavage furrow. Cytoplasm, cytoskeleton, spindle pole.
Sequence:
MDPGDDWLVESLRLYQDFYAFDLSGATRVLEWIDDKGVFVAGYESLKKNEILHLKLPLRLSVKENKGLFPERDFKVRHGGFSDRSIFDLKHVPHTRLLVTSGLPGCYLQVWQVAEDSDVIKAVSTIAVHEKEESLWPRVAVFSTLAPGVLHGARLRSLQVIDLESRKTTYTSDVSDSEELSSLQVLDADTFAFCCASGRLGLVDTRQKWAPLENRSPGPGSGGERWCAEVGSWGQGPGPSIASLGSDGRLCLLDPRDLCHPVSSVQCPVSVPSPDPELLRVTWAPGLKNCLAISGFDGTVQVYDATSWDGTRSQDGTRSQVEPLFTHRGHIFLDGNGMDPAPLVTTHTWHPCRPRTLLSATNDASLHVWDWVDLCAPR
The following text describes a protein:
Function:
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
Sequence:
MNGTEDKPVIKSFLDTDLYKLFMHAAVNKQFPDVPVKYRYTNRTPQLKLNSQAISWLKKQIEYLGDLRFSAEEILYLHRVLPQLPSDYLEYLADFKLVPSSQIKYLDNDEGDFELEIVGKWNDTILYEIPLLALVSEAYFKFVDTDWNYEGQYALAQKKAKQLISNECNFSEFGTRRRRSYESQEIVIKAIKDVQIDTQSKYIAGTSNVYFAMKYDLPPIGTVAHEWYMGIASITQDYVHANKLAMDYWIDTFGAKYAGLALTDTFGTDNYLTMFVAPYVNEYSGVRQDSGDPELYAEKIARHYEKMGIAKNTKIICFSDSLNVEKCLKYKNTADKLGLISTFGIGTFFTNDFNKLSNGEKSQPMNIVIKIKEANGKPAIKISDNIGKNMGDQATVDRVKQELGYTERTWSEGDETHRWSK