lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
ATP-dependent transporter of the ATP-binding cassette (ABC) family which transports various molecules including bioamines, neurotransmitters and metabolic intermediates. In the eye and probably in association with w/white, required for the transport of the eye brown pigment precursors, kynurenine and probably tryptophan, into pigment cell granules. In Malpighian tubules and pupal eyes, involved in kynurenine transport. Probably in association with w/white, plays a role in zinc storage granule biogenesis in Malpighian tubule principal epithelial cells.
Subcellular Localization:
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Co-localizes with w/white to pigment granules within pigment cells and retinula cells of the compound eye.
Sequence:
MSDSDSKRIDVEAPERVEQHELQVMPVGSTIEVPSLDSTPKLSKRNSSERSLPLRSYSKWSPTEQGATLVWRDLCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILINGRRIGPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPGYEQASQRSAQHLCDQFAVSSAAKQRDMLVNLEIHMAQSGNFPFDTEVESFRGVAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYIFMITSGIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSGVQNITCFQESADLPCFHTGQDVLDKYSFNESNVYRNLLAMVGLYFGFHLLGYYCLWRRARKL
The following text describes a protein:
Function:
Together with ARGOS and ARL, regulates organ growth and final organ size. Promotes both cell expansion and proliferation-dependent organ growth, in an ANT-dependent manner.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Endoplasmic reticulum. Nucleus. Cytoplasm.
Domain:
The OSR domain is sufficient to promote organ growth.
Sequence:
MRVHDQRLRFDVTPKPMGLNGSSLITARSVALLLFLSLLLLILPPFLPPLPPPPATLLLLPLLLMILLIFLAFSPSNEPSLAVEPLDP
The following text describes a protein:
Function:
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Silenced copy of A1 at HMR.
Miscellaneous:
MISCELLANEOUS: There are three genetic loci for mating type genes in S.cerevisiae. MAT is the expression locus that determines the mating type of the cell, whereas HML (containing HMLALPHA1 and HMLALPHA2) and HMR (containing HMRA1 and HMRA2) represent silenced repositories of mating type information. The mating type is determined by the MAT locus, which contains either a copy of HML or of HMR. Diploid cells are usually heterozygous for the MAT locus.
Subcellular Localization:
Nucleus.
Sequence:
MDDICSMAENINRTLFNILGTEIDEINLNTNNLYNFIMESNLTKVEQHTLHKNISNNRLEIYHHIKKEKSPKGKSSISPQARAFLEQVFRRKQSLNSKEKEEVAKKCGITPLQVRVWFINKRMRSK
The following text describes a protein:
Function:
Involved in production of the polyketide antibiotic thailandamide.
Subcellular Localization:
Cytoplasm.
Sequence:
MDNTTLNDTQDIRLPNQRPTQQPPHTQAPRLRRQIGAGPQGAVAAPVQPPRVAIVGFSGRFPGADTAEQFWQLLLEERASISELPYWHLPGIAERVQLRETFTCPGGFINDPSAFDADFFKISAREAEAMDPQHRLVLEQTWAAFEDAAICPHDLRGSNTGVFIGISSADYNGLLARSEAGAHDATGNAHSIIANRISFVFDFHGPSAPIDTACSSSLVAVHRAAQSILNGDCTVAVAGGVNLCFEPMVFIGALKAGMLSPTGRCKAFAADADGYVRGEGVGVLILKDYQQALADGDNIVAAIIGSAENHGGHANSLTAPNPRAQADLIKQACRGIDINSIGYIEVHGTGTRLGDPIEISGLKQAFAELGANPEQRCYLGSVKTNIGHLESAAGIAGVIKTLLVLKQGYLPKSLHSEQLNPYIDLAGSPFAVLQTGREWPQVSDRQGQALPRRAGVSSFGFGGANAHVVLEAVEPVIPGNEPQGAASVFVLSAKTPEALQSRIEQLIDFVQRQPQLQLAELAVSLQLGREAMEYRCGFVAHSRDSLLSQLRDSGAGEGGPPAGKIAPEPLHRALQQRDLGTLLSLWQQGATLDWRQLYEQPRPRRISLPTYPFNRERYWISEAPAASPTGAASLHPLVQRNTSDLAGQRFSSRFDGNEWFFSGHRVNGRKVLPGVAYLEMARAAVERSMVDADAVVALKHVAWRQPMVHDGGDLDIDIELVEQGEGQIRFEIRGSAADGPSYCTGVALVGSAERLVPLDLGTIAGVTNQQRLTPEQCYQVFGEMGLAYGESFRRINTLQAGNGQVLASLLRGEQAPGCELPPGLLDSALQAALGLALLEPLQAQREHQPLVPFALDRVVLGELDLLKQPCQAWVRYSADHQPGRINKLDLDICDEQGRIALRLQGFSSRKLAAAPPSMLAMTPVWRDKALIDPPQRSLARQLIVLAGAQSQDLDLLTQRCQALVGNRRQIHIVPLPVVTQDPAIALPALAGFVIELVQKSPANSLVQLVLADLEHAGPVFASLLALLKTAKNEGLIDAAQCIELQGSLQPQWLVDNALQDDERVRYRDGQRQVASWQETQLAQGTAPQWREGGVYLLSGGTGGLGLLLAEQLARQGLGVRLILASRSAGQLSPEASQRVAAIRALGAQVQLHALDIADRGAVEALIAQCEQEWGTLNGIFHCAGITRDSLLQHKNATDLAAVLAPKVAGVLNLDRASAHLPLDCFVLYSSVSAVIGNPGQGDYALANAYLDEWAGWRGAQVRAGRRQGRTLAINWPLWRNGGLQIDGQREQQMIELTGIEPLSDSGGLGFLQQALAQASDAERWMVLEGDIAKIKRFIAGQWQQDRFEEPPAPQEMPAAIALAPSTPLAASVEGDLQALAIRYFKQLLSTTLKRPLEKIDSDASFERYGADSIMLTELTRQLERLFGSLPNTLLYEYQTVRELSAYFIGQHAQRLDQWLRPEGAKASAPGEETSLIAQAPVRQRARNRQQCETPAVAGNSRDLAIIGISGRYPGAADLETFWHKLAGGEDLISEVPSARWDHQAYFDPARDRFDKTYCKWGGFLEGVEDFDPLFFNLSPREAHIINPNDRLFLETCWNLLESAGLTRQQIQQRYQQQVGVFVGVMYQQYQAFESDLVRESLVSVTSYSAIANRVSYFFDFQGPSLAIDTMCSSSISAIHAAGEALRNGDCRLAIAGGVNLTLHPKKYIGLSVGQVLGSHAGSRSFADGDGYLPAEGVGAVLLKTLADAERDGDPILAVIKSTAVNHGGHTHGFSVPSAKLQAALIDSNFKRAGIDPCTLSYVESAANGSEMGDAIELSALSRVFSAAGVAPQSCAIGSVKSNIGHAEAASGMSALSKLVLQLQHRQLAPSLLLGELNPKLDFAHSPFVLQRTLTEWPQPVLEIDGVEQPVPRRACLSAFGAGGSNAHLIIEEYSSAPIPDLAASEPGLLQIVPLSAHSSAALQQGLERLARHLDRHPQVRLQDLAHTLQNGREAMPLRLALRVSSTAQLRGLLAEILQRLQQGQALASLDSTDLPLALGNVDEVPAALASLLSGPGAAALSAGLIAAADLQQLALLWTQGGEIPWHALGHNTGAALIPLPTYAFDKQRYWLEQPSAVKALHEPLTAAGSTRHVVGQKPPTAAEQGRQLLADLLGMQPQDLSPSKPLSAYGADSIVMLQWAMQVQAQIDPGLALADIQQCQTLGDVLQRLSRDATPTGVAESVLPAQILGLLSGSTTRFPELQRLNPVQQGRPVFWFHGALGGSEIYQGLAQHIQRPFFGLQARGWMTDRAPLQGIQAMAAYYVQVIQSVQPQGPYDLGGYSLGGMLAYEVTRQLQELGETVISLVMLDSPDVTGERSARLADKTRLLQTVNMSLQMTLGQTPERFAEVLIHRDEIDLALSPADYLQQLTDLARQRGLKTSDQRLQQLMAQVTQIQQAYQVEHYRIQPLPRAAEVACYYFRNASGLWMGDLEPFFSTDSQEFAAFNHADYWQEWQRQLPNFEMIEVASANHMTLLTQPEVFRVIAQFCATLYGQRSVENAVG
The following text describes a protein:
Function:
Protein adapter that acts as an essential executor of PIWIL4-piRNA pathway directed transposon DNA methylation and silencing in the male embryonic germ cells. Recruited to young transposons, which are specifically marked with histone H3 trimethylated at both 'Lys-4' and 'Lys-9' (H3K4me3K9me3), via its association with SPIN1 chromatin reader, and associates with the de novo DNA methylation machinery and repressive chromatin remodeling complexes. Following this, PIWIL4 engages with nascent transposable element transcript to direct piRNA-directed DNA methylation. Not required for piRNA biosynthesis.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
LTQEAAPAGPSTEDPVLSPLNSLGLFQEDMEETSSMSGLAPDLSGESSGDPVCAGSGKRVLREESCQGASSQAVGAPGASPEATAHPVVLGLQTVGQNRNSVPSSRLRRQLPTEPAQGRAQGLKRVQIILHDVLAGSCPRNLCSGCVGARKKSRKSETPSEGQEGSFLWLGQSGDKPKAVGDSLQGADVASLGGPCSPLSCKDTGSGPGHPGGGWVDCDSGIEKFEYLPTVRVGTPPGSPCDPVSFPVPTGGPSLQLAAQDPLQSPELCLGGSGKASTAQQEAEHIMRPGDGDGHGASHNQEELEVVARPVSGGRPGQGLGDTPSSFLEPVASKASSGPSMRQRNSKCAKQLKMDPVPGAQDQGTNRWPDSSNQDQTEESSPGSGPRLETMRMAHGVKLVCYVGSEPVICLLGAVSYSQAGGQLPPKLEVLEDMMEASSASPAQRPRKKKRRRARGRVRRQVQNRGGPGGLSDPFHHPQESLPAPQGLPLLLSQLQPQQEKPPLDIGIRGTVVRTMQEALWSRRRKHPDLVLSEKVVEGIAAGIEAALFNLTQATNGRYKTKYRSLLFNLRDPRNPELFLKVVHGDITPHGLVRMSSVQLAPQELARWRDQEEKRGLEIIEQLQREPRSLPASKLTHKGEVEILRDEDQTLTLEDLVGPMVSIDGGPRALPATSRDSMEQHQHHFLDPSCRICTGRGRHGRGAGAAGRPGLGVGFSTAGEALMTCSAWPCLSLPPRLQMPAGPTKALPTQLPWEGSLDMFCIKRFRVRAQLVSGHSCRLIQALPQVIRSASCIAPDAVWDFLASICPAEAKDICVVRLCPQSSRDTQNCHLLYSYLNNKQCHGLAAMEQARVVLLPLPAFQPLPSRLRPLGGPGLEATHSSLLLALLLPQSGLPAMAGSGALRGKVRKMVSFNRKVEMRCYQPEDKGPHVALKGSPPPGGAMQQSQGKDSLAPRGICAWQRPPRGRGSLWGEPKTRQGPGRGLWPPKPGWCQSWHPYSASPVGHDQHRHRASCPNQALLQHLKSLVAMTQQLQASLMSPGQEELSQPPVQPPTVPGTQGLLCQPPAAPEPTGSALDSSLGPTDGAGTDSPLPGET
The following text describes a protein:
Function:
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
Sequence:
MTIPFQSSTAPTLGVEMELQIIDPATGNLTPRGPELVTFCEEHPEVGLVVKPELVQATIEINTGICKDVAQVERDLTTQLTLLRSVCRERGVSFLSAGTHPFARWRERRYTQTPRYRALVDKHVWTARRMQIYGLHVHVGMPDGDTAIQVINQITQYAPMLLALSANSPFWEGDDTGLDSCRTKVFENLSSAGLPFRFENWEGYENLINVLLETGSIGSQREIWWDIRPHSDFGTIEVRICDATRTLAEVLALTALVQCLAVYFRRLYENGEEIRLLHPGIIRENKWRACRWGLEGELIDPLTLKGVPTRKLIEQTVGEMQSLAAELGCSAYLAAIPAILASGNGATRQRRIYSQSRSLVAVVADLEAGLAT
The following text describes a protein:
Function:
Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MSSQNQARVKNRAPAPIQISAEQILREAAERQETHILDPIVKIHDAEEYQSHLRDRRKGFEDNIRYRREHIGNWVKYARFEEDNREFERARSVFERALEVDVRNPELWLRYAELEMRNEFVNRARNVLDRAVQLLPRVDFLWYKYVYMEEMVGDVPKCRTVFERWMEWMPDDNAWMSYARFEGRCGHWEQGKDIMKRYANAYPSTRSFLRFAKWAEHEAKDIDLARTVYESALVELEPEESRQARVFARFAAFEERQGEYERARVIYKHATKLLHLGQDKKPTGDKEEEVPEWEQEKRNDLYKAYIAFEKKRGDKAGIEDIVITGQRAEYEKRVTADPTDFDAWFEYAKMEEENEESLQAGSNSSTDNYNKVREVYERAIGNVPPSMEDKQHWRRYIYLWIYYALYEELQRRDLYRASKIYDSCIDLIPHAKFSFSKIWINAAKLHIRRKDLVSARKLLGKAIGLCGKERIFEEYIALELALGEVDRCRSLYTNYLKAMPHNCRAWSKYAELEKSVGESERCRAIYELAVAQPALDMPEMLWKNYIDFEIEESEGDKARALYERLLEKTGHVKVWISFAQFEGTEVGKGVDAARSTFDRAHERLKEAGLKEERVLLLDAWRVFEKTKGDAQSLAKVDSMLPRRVKRKRMRTDEDGAELGWEEYFDYHFPNDEDANAGNLKILEMAAKWKQAQQAESSSSEEEDSDDE
The following text describes a protein:
Function:
Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
Subcellular Localization:
Secreted.
Sequence:
KVREGERVRQQDSADPPTQRPTDRASRDRNIARPDRSLRPGAPHPAPHPAPHLAPHPAPHPAGPGCSPPARSPPPHHPLRPARSVQPVYTGPVRSCPVPSCPVLTAQPLIPPPTPCCEPATRLSPGPLQTAPRPLAHSLRRSPVRPPALRIHTPRLEEREPPKMPRGTSMLFLSLLLCFAVTKALGLVSAGKEKRGWTLNSAGYLLGPYAVDSHRSFSDKLGLAGKRQLQTDEETRLGTWGRPVADDNIVRTVVEFLTFLRLKDAGVLDLPLTASSEAGGPS
The following text describes a protein:
Function:
Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
Domain:
The molybdenum cofactor biosynthesis protein-like region may not be functional.
Sequence:
MRAMFRTPRMPQRKTAAILVIGDEILKGTTRDTNSHFLCKRLHKLGVNIRKISVIGDDISEISREVQSASGAYDYVITSGGVGPTHDDKTYLGLAHAFTDQMQFSDEIRQAVNRFLPTYTAKKRAEGVGEGLEEAVRLATEKLCTIPKMSQLLWGTQKINGSLSTFPVVRISNVVALPGVPKFCERAFDELQDQLFPIEERQSLCFETLYTDLDEFDFSKKLTDLAAQFEDRNVQIGSYPELKNKFFKTKLTIETESSETMEAVVTSLRELLAGHIVYYDSHAWLDIVTKWKAFKKRKASENQIEFIQKLNEAESIVEEIVEKYPLEQIALSFNGGKDCTVLLHLLRLKVDEKYGPSTPIQGFHIMVEDQFPEATQFIIDAAKFYNIQVLEFPGPLKTGLAALKKTRPSIIPVLMGSRATDPNGKYMKTPVEWTDSDWPQVLRVCPILNWTYTDVWHMLRGLCVPYCKLYDQGYTSLGGRDNTVKHPALRIVSSDGREHYLPAYKLHNDAEERCNRSNI
The following text describes a protein:
Function:
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MMKLFTKDKDGHFIREINGIKLPFPLTEFMKVRKLGYILSALLMVISLFFIITKGFNWGLDFTGGVVFDTHFSQSANLEQIRSKLHENGIESPIVQTTGSVQDVMIRLPASNNDSTIGEHVKSMLQNVDKDIQIRSIEFVGPNVGEELAQGAVYATLATLAMVLIYVGSRFEWRLGFGSIASLAHDVIITLGVFSALQIEIDLTFVAAILSVVGYSINDSIVVFDRVRENFRKIRRLDTIDIIDISLTQTLSRTIITSVTTLVVVMALFFFGGPSIHNFSLALLVGIGFGTYSSIFVAIAIAYDVGLRREHMIPPKVDKEIDELP
The following text describes a protein:
Function:
The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization; Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
Subcellular Localization:
Cell membrane, sarcolemma. Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Nucleus, nucleoplasm. Postsynaptic cell membrane. Secreted, extracellular space.
Sequence:
MATRKNKACETVMRSEIRTCRSPQPHLHRCHAHLVLRNVTVGPCALLLAVGVLVLAAVLPVFAAGVGEGSAGGAGWAESGQQVGWGIPDMRATAGRVFMYQVPQDVFTTSVDNYKVTEVDSDKLPHWLEFDQSTRTIFGVPMVTDEGLYYITVAAVATESTQSTSDIFQLEVVLTDFTAQPESLQFDPIQGDFLQVREKKTNVEMTEEDSQQSKTVCYNGETRAVVRLSVNVEDLSARQRVDLVAKFADFVRRDPQSLKLTQRRSSNVGKLLEESVLVAGPGNANISTVLSLHTSTELSWRLSCGLFRGVEDFSKVMEHNAVEGVLSRVLGYGVIGWQVTSSASPEQRRRRQAAGFATPMPTPTTTLFPPSSIPTATPVSLSSQSAFSTAPLPSLPSLSTQPLSPTMVTSPTLEATGSLPFLPVSSSTGISPSPVATVMPASSTPVLTSMSPLAPSTASLGVQPTVTTPDFSLEPSSPALSFSPTVEISGTSSLSLPTVGFETTAIIPTSVGEEPTTAVQPSLSTLPSTGISSSMELSTTPSITAVFTTSSQLSLTPSPTPGSTSALATITEVQSSTPVSSIFPTLSSTSAVATSRKSDAASVVTTSSALSSGFPSTTALATASRLATSTMFETISELATLSRLSTSSASMVTPELATSVLATSMSATISTTFSTLSGTLSAPTFTTGLATSSAFAASRFSTGSASTVTPELATPSVVVTSTAVIGETATASVYMSASPIFSGFAPSTTAPGSLTSSSLTSFLPSSPSPSPTPTSFLGDQLTPSTPLVSPSSTSSLSSVVFTVPSTSTLSTLPTPGLPVVSSTAALASSSTLSTLPTPSPAVVSSTVAVVSSSSTPTVPPNQPPLLVNHLDHLQVAAGQVYYSRVPYDTFYDMEDAMNTRGLTLELVALDGTTWLLLNDDWQALYGIPPLDSANQIYHFILVASDSQGLATRDSFQLTVTQPPTPSHIFTAIIDIDYTTFQPDLLSWISLSERISTHFRDRTTNFILIDSVQEGSVVFSWSNISLSSTTCQNTTIQRLAEELINPDGTVNPTFVASLLPEYPVTEARVRYQGVCDLAVVSPVPTTAETLAPVPLSHSNHLLGTVVPAACIAAIILLLGVVACCLYRNKKPGKKLPKYDKLTLTKNRKPIVLEDEVEMKDTKPSKPIVLPDEKPPATQLPTRRPAPPPYRIPDTQQLLSGMEPQASALPPPPRYTAAVPRKPPPPYRLPPPYTPSASPLPAPLSFADTKV
The following text describes a protein:
Function:
Required for selective autophagy activation by ubiquitinated proteins. Implicated in sigma rhabdovirus multiplication and necessary for male fertility. Involved in activating transcription of Drs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MANSLPFKCYLLTNNGQDKEIRRFALDSDVVGNFTYLQEKVRVVYPQLLRESFTISYIDEEGDKVTVSSDDELVAALMFAKRKDDEPFRLIVQTTAATSGAKPETATPSAGTGNCQGEIHWGVTCDGCQGAVKGFRYKCFQCPDYDLCGKCESAGQHPGHILIRVTGAMPAAFQAMKHALNGGPEVPHWRRGKHGRYHHQHGHGWNAWCPSGMNVEVDPQTTAAGSNKGASKTEAKPQCPYKFYMDQAKETATTIHAQAKETASIFNEQHPEYLAGLGSTIASVMEGLGFGSVGGSCPRASTQKPEAKKQETKKEETKAEEKDSTAEAKKEEVIIPVVIEKEETPTNAAVVNPYAHLVDAARAVEVASAKAMADFARQAAVQTGVAPKPAETMSFFQTAEAKKDTPFAVACRARMTAPQAPPQAVAEAIAEVVAQAPSQAIAEAVAEAAALAPTQAVADAIAKVAAEAPSQIAAQAVAQAAEDAYKDSLVSQQTVTEPTSVKPKHNESGDWTIVDHGMEHSSSPPPPSVPASQFVGARPKEPTAEKAPLHPDPFISAALETMLAMGFTNEGGWLAQLLEVKGGDIGKALDVLQSQFQRQQHQ
The following text describes a protein:
Function:
Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing, correct growth and development, and for resistance to DNA damage induced by UV LIGHT.
Miscellaneous:
MISCELLANEOUS: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
Subcellular Localization:
Nucleus.
Sequence:
MSTNSTPRKQKLSNSKSLQNSPISPTVKKTNSFPLGNNIPTNINRSKKDKNNNSNNNINNNNSNGIGSNTIINSTPIATTPVPPLPFIHSSSSSSSSPSPSSSSSSPFPKAKKSPSLSINQQQQQQPQQPQQSPQSQQSPQSQQSQQSQQQQPQQPQEQQEPLPNLSFLRNQEPDKNVLPTSRKRPPSVMPSTPNQSSNSSSLNSSLNFSSSNSSPSPTSTQSNNSRFETRSQNDQYENNNNNNNNNNNNNNNNNNNNNNNNNIECIVIDDDDDDDDDEGNSIKSTHTSTQSTPIRDRRQRDNKWTINPLPQFQREIIDVDTPSPPNESLSIVSQTTTNTITDTTSIQTPTLIRQSSSLLSSSSSLSPSTTSTPLTQNNINLQNAQVIATMTAPMEIELPTIVQLEPLFSSEFTTSTQNLFIQTPPFTSTLTLPTTTAQTSQTLFTIQTSHDINNNNNNNNNNKNKNKNKKEIEKEKEKLREALKQKLKEYENENEKEREKERKREREIEIERERKERERKEREKERKKEKEREREREERERKEIERKEREREEREERERKEIERKETERKEIERKEIERKEIERKERERKERKEREEREEREREERERKEREEREKEIEMEREKKKEKEKEKEKEKEKEKEKEKEKEKEKEKEKEKEKKRKENEVENEIEKERREKNDSYMVLNYHHSIDDHHSESESESDSDQDSIYSISTQELSSVISDNDFCDSDNEKVANNNRTVGETFLNDSRNNNNNNNNNKNNNNKKIENDKNQLIERERLISAFNDKAFLYALDTIREVLGGIDFKLKVSKEQIIEISTNAKKPLNILSEPEQQQQQQQQQQQQQHQQQQQQQQQQQQQQQQQTTKTTTTTNNTTTTTAETEKPKEVFLLKKPIKIPYGRDCKKRLIRRFHGTSRNPLFHKNLESTLKLLKRAKFDWASIEFDTKSYLMNCNCKTVCHKSERMKDNPTNKLQNNNRNNNNNNNNIINNNNNNNNKNNNNKNNNNKNNNRNNNSIAKKIGTNNNNNNTTIIKNNNNNNNNNNNNNNNNNNIIKNNNNNNKNNNNNNNTIVKKIETIKKDINKKPTKTTTTTSSSSSSTSSSNSLTVIKKPVKKINGSQRICLFEDDFDVGIGVPVTTGTSETTTTRASSIRRKMNISNIFDDFTKKPRQNKYNEIEMPDLFASKECNYTLEQQAPFIRAQKLLLTQQHENNLYNGKRFMKYDEWLDLYHGEMRSSIQNPKVLKHYISFSQEVYGEAEPTLLRHWIHLGLIKPTDVFCDIGCGIGNVLFQLAAQVGCRVIGVEIRKDLYDISQSMLEIYKKRSLELGLHPSTQQIKIYNCDVKGSLEFDFSEPNVFFMHNTCFGPELEISIMELFKKYSKPGTKVITMKTLCPRFKPSDKKTKPWGIFKYPYESYEMEEGSLSWRSATNCSFYSFTIDDKDSDIVTDQTHLNRVILSTPKKKHSKLQLFSSSSLPSSPPSSSSSSSPPNIATNTTTTTTTTTTTSPSSISLPSPYLSPSKKTPNSNKRDRSDIDNSNSDDGDENNNNININNNNNNSNNKPIKLKLSMDHSIDNQSNSESSDTDVEYMPWSKRNNRKKRKSLSYSLDSYLSSRISPSLSLSTSSSSSSSLDSSPYSSPPSSSSSDNENDDDNGDDEDDSSSSNDTKLKEKLLLMKNNEKIGGAPPLTRRNANSDTNKLVQGCYQSLSSYALPKEESQIHKLQLQAKLLEHKNSLVLKHQKSIHDQQKRLSRKQKKLAKKNKKKEQQLQAQAKTINYNNNNNNNNQNDNQVNHNNLNENEINTDLINGYNNNNNNNIINNDNDNDNDNDKDDDKDSNNKDYNNINDNNK
The following text describes a protein:
Function:
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSTIFQDLVDSTVIKNAVQGQFTSLVSNNLVVSKVNSLHLFEIEKIQKDESSFPLDDSLQNEFSTSIIDESQAFMETNMHLIRTNEQTTYVLRLVSQVKVFGTITEISALKGKGSNGCDLLIMLTDYAKVSTLEWDMQSQSFVTNSLHYYEDVKSSNICSSHTPTQLLVDPDSDCCLLRFLTDMMAIIPYPANEDLDMEEAAIENSKISSSYAYKPSFVLASSQLDASISRILDVKFLYGYREPTLAILYSPEQTSTVTLPLRKDTVLFSLVTLDLEQRASAVITTIQSLPYDIYASVSIPTPLGGSLLLGGNELIYVDSAGRTVGIGVNSYYSKCTDFPLQDQSDFNLELEGTIAIPLTSSKTETPFVVLVHTSGQFFYLDFLLDGKSVKGLSLQALDLEINDDFLKSGITCAVPAGENLVFLGSQTTDSYLLRWSRRTTNEEVRLDEGDDTLYGTNDAEMDDMLDIYETDESVGSKRKIAYENGPLRLEICDVLTNIGPITDFAVGKAGSYSYFPQDNHGPLELVGTAGADGAGGLVVFRRNIFPLIAGEFQFDGCEALWTVSISGKLRNMKSRIQAQYSNPELETYLVLSKEKESFIFLAGETFDEVQHSDFSKDSKTLNVGSLLSGMRMVQICPTSLRVYDSNLRLTQLFNFSKKQIVVSTSICDPCIIVVFLGGGIALYKMDLKSQRLIKTDLQNRLSDVKTASLVSPDSSALFAKLFTYNETLNAKGQIANGMNDSASETDLDIQPNHKTSNNDQMGYDQSVSADDVPEVDNTIVTEKNVSNLDQESLEKHPILFALTDEGKLKVYNLADFSLLMECDVFDLPPTLFNGMESERTYFNKESSQELVELLVADLGDDFKEPHLFLRSRLNEITVYKAFLYSNTDKHKNLLAFAKVPQETMTREFQANVGTPRDAESTMEKKASSSVDHLKMTALEVVGNHSAVFVTGRKPFLILSTLHSNAKFFPISSNIPILSVAPFHAHHAPQGYIYVDENSFIRICKFQEDFEYDNKWPYKKVSLGKQINGIAYHPTKMVYAVGSAVPIEFKVTDEDGNEPYAITDDNDYLPMANTGSLDLVSPLTWTVIDSYEFQQFEIPLSVALVNLEVSETTKLRKPYIAVGTSITKGEDIAVRGSTYLFEIIDVVPQPGRPETRHKLKLVTREEIKGTVAVVCEVDGYLLSGQGQKVIVRALEDEDHLVGVSFIDLGSYTLSAKCLRNLLLFGDVRQNVTFVGFAEEPYRMTLFSKGQEALNVSAADFLVQGENLYFVVADTSGNLRLLAYDPENPESHSGERLVTRGDFHIGNVITAMTILPKEKKHQNAEYGYDTGDDFSCVMVNSDGGLQMLVPISDRVYRRLNIIQNYLANRVNTIGGLNPKSYRLITSPSNLTNPTRRILDGMLIDYFTYMSVAHRHEMAHKCGVPVSTIMNDLVELDEALSYM
The following text describes a protein:
Function:
Involved in sporulation. Essential for completion of the nuclear division.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Sequence:
MKKQILIVAAQSILCSTVFGERSNVGLSTEELGGDSILYFNEDPIVIEIDKKAIDKKTLEQLASTRDVVLTDLPDTLEFIDFNEYAKMKSKSDMLLEYINEYEFDDFERSSEGGLEEEEEEDLIYDFNAQAEDLGKLGSNIYEVVEEKNIVNTYDGNLINASTTESTTTIRPFVTSHSYVASSTPYSNISSLNEDYDNASNFLTPTTVALAVLLTILLFIQAY
The following text describes a protein:
Function:
May assemble to form large pore channels with gating and ion conductance likely regulated by membrane lipids.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDAFQSILKFFLNQKTAIGYSFMALLTVGSERLFSLVAFKCPCSIENTAYGLVFLFAPAWVLLILGFFLNNKAWRLFTGCCMNPQKIFPRRRCCRFFYVLGHITLSSLVAPVMWLSVALLNGTFYECAMSGTRSTRLLEMICKGKPKECWEELHKVSCGKSSMAAMDSEEVRLSLQAQSQILGWCLICSASFFSLLTTCYARCRSKVSYLQLSFWKTYAQREKEQLENKLLEYANKLSERNLKCFFENKKPDPFPMPSFAAWEAASELHSFHQDREHYSTLHKVVDDGLEQTPQEEETTMILVGTAQSL
The following text describes a protein:
Function:
May play a role in magnetite crystal growth and size.
Miscellaneous:
MISCELLANEOUS: This bacteria makes up to 60 cubo-octahedral magnetosomes of about 45 nm in diameter which contain membrane-bound crystals of magnetite (Fe(3)O(4)); MISCELLANEOUS: Expression of just the minimal mamAB gene cluster (MGMSRv2__2365 to MGMSRv2__2381), including this gene, is sufficient to form a minimal magnetosome chain with small magnetite particles.
Subcellular Localization:
Magnetosome membrane; Single-pass membrane protein.
Sequence:
MDFRPDQVVARIRGAVEGALTAQSVLGIGGALVLILVVIALLPDRFTRGEGKTATAVSSGAAQALPAALPGLSPFTPAKPLQFSGRVTQVASIGNDVGWGQVHVWIDNGTGALQEISVAPQSYLNQIGCPSFDGARISGIGFLFDAGRPNAELYAKSVLVGGRTCKLRDDEGLALWMTVQ
The following text describes a protein:
Function:
Probable nucleotidyltransferase that catalyzes the formation of cyclic dinucleotide second messenger in response to some unknown stimulus (By similarity). Does not catalyze the formation of cyclic GMP-AMP from ATP and GTP.
Sequence:
MSTANHFQRILEKLSISDNERAVYTKEAEEIQNYVVDELKRVDKTFRQVFDGLSLGGSYLDRVKLNLPDEFDLHMKLKFPFDIRPTRIDQGFIYLEADLTVINPQRIHRIVLQDWLRNAFRKVFRSNQTIATTSNRVYKLTYTLEGYGCAHTILAVCGSRSISFDLVPAFEFSGSQWPFDICPVPADVSNNWPWFAIPQQKKKSAKPRTTFMVCAPHWEREIMKGKDNLKNVLRLMKGLRDAHARKLPHLSSYMLKTVLLHRLESADWERDLGTLLVEMWSHLVDHLRARRLEFFLAKDHNVFNRMNQNEIKICLENASTLLRKLCIAQTCGGSYHHVAQLFNIPN
The following text describes a protein:
Function:
Involved in spliceosome assembly.
Subcellular Localization:
Nucleus speckle. Nucleus, Cajal body.
Sequence:
MAEDLAKQLAGYKAQLQQVESALTANGENDDLLKLKKDLQEVIELTKDLLSSQPSETTDDACDITSASGSQSWKVGEKCMAVWSDDGQWYEAEIEEIDEENGTAAITFAGYGNAEVTSLLSLKPVEEGRKAKEDSGNVPMSKKEMIAAQREYKKKKALKKAQRVKEQEQEREDQKDKWQQFNNKAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ
The following text describes a protein:
Function:
Polycomb group (PcG) protein. While PcG proteins are generally required to maintain the transcriptionally repressive state of homeotic genes throughout development, this protein is specifically required during the first 6 hours of embryogenesis to establish the repressed state. Component of the Esc/E(z) complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The Esc/E(z) complex is necessary but not sufficient for the repression of homeotic target genes, suggesting that the recruitment of the distinct PRC1 complex is also required.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MAPAKKREKDSNPDGSAANGIIGLTHGAPDASNAGSTVPPTAEGQVKLNGHQQEQELFLQAFEKPTQIYRYLRNRHETNPIFLNRTLSYMKERMSRNNKKRISFQVNSMLESITQKSEAVSQNYLHVIYDSLHEKLPARLDNESGEDLLQEQLLCEAGESVSVETTLYKITRSKRKDSTLDFQELLSKCSQIVYNPKDRVGEHATISIPLQTMRPMGEQHTLYKLLFRIKVLSPSTCNDENAETPPNKRSRPNEKMFGSELILYEKSSGFITEGEYEAMLQPLNSTSIKSFSPKKCTWETMPDSYIPLSLTYDVYQQSPMLKFHLTLSNEQLPEMISAPELQRYVQHLDAVAEMNYNNNNYNNNNNCSGLKNGSGGGNSTVCKTTPEHIQIVYNFMYSNNTRQQTEYTQELNCPWCGLDCLRLYALLKHLKLCHARFNFTYQPAGSGARIDVTINDAYDGSYAGSPYDLAGPSGSSFARTCGPVRRTSVTSLMVCRPRRQKTCLDEFLELDEDEISNQRSYITGHNRLYHHTETCLPVHPKELDIDSEGESDPLWLRQKTIQMIDEFSDVNEGEKELMKLWNLHVMRHGFVGDCQLPIACEMFLDAKGTEIVRKNLYRNFILHMCSLFDYGLIAAETVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDNTVLNKRQRYSDGSPGTGIGNGHGGGSGSGANRNKSNNHSLPATSNNASSSSSNSKRAIARRRSTSERTKASGSTGGGAGGVRTRLSVPAKYERR
The following text describes a protein:
Function:
Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
Sequence:
IMVANGGLGNGVSREKLYLLFSGFGTIQDIQMKPKRSYSILNFDDVNDAQIVFNKFNKFCAIKDESEKDVHLCLAFIEKMPYLEDSNAMHYPQGLEIVNDFVSENEEKMFLDYCDWGEEDSISLKNRRVRHFGYEFNYKEKTISKLNGLLNRIPQFCCDLLKKLKQLNYVTEDFDQLTVNQYNPGKGIPNHVDTPEVFEKEIAIISLGSSIVMDFKHPDGTHVPIVLPRFSVAILKNESRYIWSHGIAPRLYDLIKSETGLTLARRSTRISFTFRKIKTKLLGNFLFTNVMKFPKLNCVAITVDNDKLAQVYNTIAPHFSRTRHSPWPSVVNFLNRLDPYAIVLDVGCGNGKYLNTRKSDLFMIGCDASPTLCQIGSSVGEVQICNVVALPYPDCTFDACICIAVLHHLASQERRSLAIKEIVRVLKVGGQALIYVWAMEQDFAGVKSKYLKSVKKITELTEFHKVDDNLSLPVHNSKTTFKYCDNLVPWTLQTEYPTKDDLNSVEVYKRYYHVFCKGELVELCRQFDSSLIVSNVFYEEGNWCVEIIKTNKIETILL