lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the qa gene cluster that mediates the catabolism of quinic acid (QA) and as such, allows the use of QA as a sole carbon source. Its function within the pathway has not been determined yet but it probably plays a regulatory role. The qa cluster encodes 3 inducible enymes (qa-2, qa-3 and qa-4) catalyzing the first three reactions in the catabolism of quinic acid to protocatechuic acid (also known as 3,4-Dihydroxybenzoic acid) (Probable).
Sequence:
MTSRTTTATELDEIYTFAVQLGKDAGNLLMEAARLRFSNNNANHDKESTTQEFTEKDSAVDIVTQTDEDVEAFIKSAINTRYPSHDFIGEETYAKSSQSTRPYLVTHTTPTWVVDPLDGTVNYTHLFPMFCVSIAFLVDGTPVIGVICAPMLGQLFTACKGRGAWLNETQRLPLVRQPMPKSAPGGCVFSCEWGKDRKDRPEGNLYRKVESFVNMAAEVGGRGGKGGMVHGVRSLGSATLDLAYTAMGSFDIWWEGGCWEWDVAAGIAILQEAGGLITSANPPEDWATAEIPDVKLGSRLYLVVRPAGPSEGETAREGQERTIREVWRRVRALDYTRPGA
The following text describes a protein:
Function:
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
Subcellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MANNPPQPSVGYPLTITPKIDTSTPEKSPIPPSPPILAPRFPPPILQQDQVLSPSIKTPNLLSSANGVNIGSPIPHLSTPPGPPVFSSPVRPAAVPFRTSPATPQPIAFSSGSSLPTSSPPHFLNGSPELQHQVPQVSEDSMPAEELSCILFSAHKVLRQKKLANVPSLGFGALISPGREISPAPQIIQRDPHRCQNCGAYANLYCKILLGSGQWQCVICRKLNGSDGEYIAPSKEDLRNLPELSSPLVDYVQTGNKRPGFIPVSDSRMSAPTILVIDDCLDEAHLQHLQSSLHAFVDSLPPTARIGIILYGRTVSVYDFSEESMASADVLPGDKSPTQESLKALIYGTGVYLSPMHASKEVAHQIFSSLRPYKLNIAETSRDRCLGTAVEVALAIIQGPSAEMSRSVVKRAGGNSRIIVCAGGPNTYGPGSVPHSFSHPNYPHMEKMALKWMEHLGHEAHRQNTVVDILCAGTCPVRVPILQPLAKASGGVLILHDDFGEAFGVNLQRASIRASGSQGLLEVRCSDDILISQVVGPGEEAHVEPHETFKNDTSLSVQLLSVEETQSFALSMETKREINSDCVFFQFAIQYSSIYIADISRVITVRLPTVDSVSEYLESVQDEVAAILIAKRTLLRAKNSSDAIDARATIDERIKDMALKFGSQVPKSKLHRFPKELSLLPELLFHLRRGPLLGNIVGHEDERSVLRNLFLNASFDLSLRMVAPRCLMHREGGTFEELPAYDLAMQSDTAVVLDHGTDVFIWLGAELAADEGRSAAALAACRTLAEELTELRFPAPRILAFKEGSSQARYFVSRLIPAHKDPPYEQWLKGMLLG
The following text describes a protein:
Function:
Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
Subcellular Localization:
Cytoplasm.
Sequence:
MSHMNVAMMTSGGLAPCLSSSVAYLIEFWAQALKEGKISGLSIRMYFDGYKGVLTGDSTVISPDIYDDCACLHELGGSPIGNSRVKLTNVKDCMARGFVKEGETPLEVAAQQLIKDNINVIHTIGGDDTNTQAAELSKYILEKHGGKVVVVGMPKTIDNDVVPIVQTFGADTAAEQGAIFFKNVVSESSANPRMLIIHEVMGRDSGYLTAATARKYRDSIKATKFVGPGFTTTSTSRDIHAVWIPEVNVNIAEEGERLKKVMDDHGCVNVFLSEGAGVKDIVAEMEAKGEEVPRDAFGHVSLAKINPGLYFSKNLATAVGAEKTLVQKSGYFARSAASNAFDRKLIRDCAEKGVESAIAGVSGCMGQDEAKEGTPIRAIEFERIKGGKPFNPEQAWFQEMLKEIGQA
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
Subcellular Localization:
Nucleus.
Sequence:
MASSANLSADSSAEEQETLSDDSHKNGKRKHTSDSDSDQPQKRSGMSMAPAAMDGSQGAAATTAAGGGAAPFSQFSEKSFRMMKQMGYKAGTGLGKTGQGRVDLIETSSQKGRSGLGMKLNELNTAAEQWDGAEERLQIPEVCSWLVNVHAEAGSPGITREQLDAWIRVGPRKLLIDDEHRYCEPDVLAQILASKSVFNNLGADDMRKARSKSNPFELIKSNIFINRAAVKMANMDSMFGFMLTSPVDRHGQPLVRDHDLFYFADVCAGPGGFSEYVLWRKRWYAKGFGFTLKGAYDFRLDDFSAGSPETFDPHYGPKEDGNVFDPANIVGFTEYVMTQTETGVHLMMADGGFSVEGQENEQEILSKQLYLCQLIVALAIVRPDGHFVMKVFDLFTPFSVGLVYLAYRCFREISICKPNSSRPANSERYLVCKWKLPQTDLIQRHLEDVNRQMYDNRNANIDTLELVSEEVLRADATFHRYVCDSNNAIGRNQIAALLKIAAFCRNRDLAEPRQMEVKQKCLALWKLPDGIRKFANKGDPDQYVAKLYKEWNSLTKEVCQVEKRVQNPELRQTFPSVYDWCFVPIGTVENAGKNLRTILLGKGGKEVYRFEPKQCSWIPVTEVSIELPPGTIIYAEIVRELQGQGKSQIVIHTLHIIDGLLLGGENIRRLPLRQRLARCQQFAKALNKPLKGTVADSTNGTAVTVQIRAKRLYGLHEIEHFFGSLETYSLKTGPPRLGYRVRNLIDPDRFYVPYGLLFLKETKPDYMKSLSKTRRMFYYYHVKTKSSRYPEQFEQANHEPETMALFEETYHSRLLWRWETVHQVDPEYGADRSADSVYRVDFRKYVRENYEPGVN
The following text describes a protein:
Function:
ADIPOR-like receptor involved in zinc metabolism either by altering membrane sterol content or by directly altering cellular zinc levels.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSEERGMKEQTISEMAQEMAHTTSEGLKKRIRKLYTFDELPAWQKDNELILSGYVRETNSVKECLRAMTYFNNESINIYTHLIPGVAYLVLFLIFADLVLAQLLPGLDAGEHRMLRFYLLGAFTCLACSSCFHCLKQHSEPHSRLWSKVDYLGILAQITCSTISLLYYGYHSYPSHFVFFSTLTVALCSACAVLVLNDSFNTVAFRPLRAFLFMAFGLSGVIPVLAGSYQFGFAEWAARIQLKYVLYEAVFYITGALVYGFRIPERFAPGKFDMVGHSHQIFHLLVVLGTLCHFRAVTGSYIFICTGKHYSSLLMFI
The following text describes a protein:
Function:
May be involved in the regulation of cell differentiation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRTSNHLIGLVNFLTFLLSIPILGGGIWLSSRANSTDCLRFLQWPLIVIGISIMVVSLAGFAGACYRNKFLMWLYLVVMLLIIAALIGFIIFAYAVTDKGSGRTVLNRGYLDYYLEDYSGWLKDRVSDDSYWGKISSCLRDSGACRKIGRNFNGVPETADMFFLRRLSPVESGCCKPPTDCGFSYVNETGWDTRGGMIGPNQDCMVWSNDQSMLCYQCSSCKAGVLGSLKKSWRKVSVINIVVLIILVIFYVIAYAAYRNVKRIDNDEPAGEARMTKSHPSHFHL
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MAAVEGRGRQRAMEPDRPELPRPRPRHRAAVRPEPVRARPVGPPPRPRARHVRAMGDPADLLLPPPRPRAHAAPPVKPARYGWLAACLYLCVCAVLGRAAMLNRLWIRPPPEQYTVLPAAIVAALVITLLLRRQKHPPLLDQQIADEAEQIVAILAPVPLVLAVSILDANQVGAAVAAIRSSMEDNTRTSFAISPPQSDSDFDGGGSSSGNDEVNANVWYTSIHSLETGDAHLIDPVFIEQLQEMTGGLTEADAVEVMRRVFRDAQESGGFYRLSDVMDNQRILHAGTEILAHPHALTDRSTGTLVMTSKIIVKLLHLIWFELQGQNWQLSQEVKKECFRVVIGQSVEKLLEVALAFSNASWSADHTSQMLTIFDALVDVLYNIGALPFNRFEFISNGVADMADMTLNRFDSIHNVVAHIFCKMVIDFRGILEGITNDMHSSRESNIRPTTVLLIRYLDFFYRNGEMLQSVLGTEDCTIELTMINCWVSRIMEDAERTFQDKGQRYIFLLNNIYYVLREKCHPGLLLPSLVDNLDSLIQRYIKKYLDECWVPLIIYLDGESLKKPSRSSLDKFTEEFFSICDHQMTWKVRTELKKALREKISKLIVPKYGNFLKALQANASSRWPSPLKGMWLARSEKPVYTDEQLEDIVKQIFER
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of SELE/E-selectin and VCAM1 on the endothelial cells surface at sites of inflammation. Positively regulates EIF4E-mediated mRNA nuclear export and also increases the translation efficiency of ODC mRNA in the cytoplasm by competing with factors which repress EIF4E activity such as PRH (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPPRQAATLAEHPDFSPCSFQSKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE
The following text describes a protein:
Function:
Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose. In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator. In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription. Binds the consensus binding site sequence 5'-CGGANNA-3', of which multiple copies are present in all HXT promoters regulated by RGT1.
Miscellaneous:
MISCELLANEOUS: Present with 195 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MNELNTVSTNSSDSTKNGGTSNSPDDMDSAAAASHAIKKRTKASRACDQCRKKKIKCDYKDEKGVCSNCQRNGDRCSFDRVPLKRGPSKGYTRSTSHPRTNEIQDHNNSRSYNTFDNSNNTLNNNTGNSGDNGINSNTVPSTPSRSNSVLLPPLTQYIPQAGGIPPSFQNPAIQSTMPAGNIGQQQFWKVPYHEFQHQRKGSIDSLQSDISVRTLNPNEQLSYNTVQQSPITNKHTNDSGNANGSVTGSGSASGSGGYWSFIRTSGLLAPTDDHNGEQTRRSSSIPSLLRNTSNSLLLGGQPQLPPPQQQSQPQAHQQKLQQGQNLYSYSQFSQQQPYNPSISSFGQFAANGFHSRQGSVASEAMSPSAPAMFTSTSTNPVNVAQQTQRPQGQQVPQFSSELDGNKRRQSAPVSVTLSTDRLNGNENNNGEINNNNGSNNSGSSKDTSQHSQESVTTPAALEASSPGSTPQRSTKKRRKSYVSKKTKPKRDSSISITSKDSAHPMTTSSTIAYGQISDVDLIDTYYEFIHVGFPIIPLNKTTLTSDLLLVNTQPISNIHEVNSYVILWFRNSLELLVRVALKQKPGGKFFDNIVGVALSPSNDNNKAGFTTATARDDAEKTRRDSHNEVQDTLEVQSVFIAALNECFQKIVDIHPKFRENNDQISPKIKVIYLSTFILLNYILAFVGYDNSFVLGMSVTIFNEFKLYKLLLFPEPDINDVKPPVDEEVSTGNGNTKTSEFEIGSESAGHMNPSNSPNSMDENISHYSVLFKRLYVLLSVFDSLQSCAFGGPKLLNISIQGSTERFFSNDLGSKWCLEQSQLRLKSVLQSLKLGELMSELTRNRISMNGNRKPGFDITNSSSLLSEYVETQPLSVAQLFCKLLIGKHNFINCLLSLYDSEAGVYSDLTLDLSSKIADSLCSLISIILQVLTLILRLNPTNSIDFNYRPPNPPANNPTVQEGPSAMGSSPVAGNLSAAPPSEGNPDFYKKLLGLKQDTGTILSDLCRGIISPFAIAILHEVYNITELVKQMPTSLISIMMTATTTQNTQDTKKSQDLVMKLSNSMNEVVQITSVLTMIKPFKIFEHELNKPIMSLTGGLSSTTRNDVMWPKSGQGLRESSVMKTLLDERRTSGTQPTTAPVAAEEPRLENVALENFVSIGWKLLDDSELGWY
The following text describes a protein:
Function:
Required for swarm cell differentiation. Plays a crucial role in regulating the degree of cell flagellation.
Miscellaneous:
MISCELLANEOUS: This protein is functional in undomesticated strains of B.subtilis but not in laboratory strains, such as 168, because of a frameshift mutation. Therefore laboratory strains of B.subtilis are unable to swarm; MISCELLANEOUS: The frameshift in strain 168 is caused by a single insertion of an adenine in the codon for Tyr-12 which leads to the premature truncation of the protein in residue 13. In addition, the C-terminal section of swrAA was predicted to be an ORF (yvzD) by the genome project.
Subcellular Localization:
Cytoplasm.
Sequence:
MKRASIVREKKYYELVEQLKDRTQDVTFSATKALSLLMLFSRYLVNYTNVESVNDINEECAKHYFNYLMKNHKRLGINLTDIKRSMHLISGLLDVDVNHYLKDFSLSNVTLWMTQER
The following text describes a protein:
Function:
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
Subcellular Localization:
Chromosome, centromere, kinetochore.
Sequence:
MADLQISAAHIAENEPTLYHDEFRVRLVDHRVLPIVGNDSLFAQQQMVVIDYPDVEKPRFEDVDEDKENTIHTADTTLQAGGGSPLKFNFLTLDKLKEGDADLFNFKVSIRTITENTFPVNPIPVDRAFAIRQRLHNSDLPFFDADDKILPSSPIFFVCNASDEKRTVYVGIQRSASTCRLFNTECTGGLDVAGRDAILNNFDRFSLIGDKKCSTRMQIEILRPRLHKKEDEVDNTVDAISTLSVDYSTNEYDIAQMPSSTAYATLNFSPGWCDPRVDYDLKTRDLQLMMVMARALHSDIPFDWTHAGERKKKDSEIQSEVRALIANTNQQVTTDESKRYIDFTERLWEILRECRSNELLVKCLQIIYSAVRSKSINTILHDDNYSSLATLIRDSCKGKEVRPPRLEGLQPIDTLLEIAVEKFRRDLVTEFVKRSFVASEGDIRDMLMRSLERVKATKDKVVDDTRALIPLHLGLQTISHLEGTLILTHRNTLAKYTKDVITRYMSKEITNFHDVNFELRIPLIQVKPEIIPGMKPASFSTEVIYKCKDGNQKGNERARAHLFLARTPPLRGLEGVLANIDDPSNRYVATVTKCTTLTMKKKIVKKDGRSEA
The following text describes a protein:
Function:
Acts as a methyl group carrier in the anaerobic acetyl-CoA pathway (Wood-Ljungdahl pathway) of carbon monoxide and carbon dioxide fixation. Binds the corrinoid 5-methoxybenzimidazolylcobamide which is then methylated by the AcsE subunit.
Sequence:
MPLTGLEIYKQLPKKNCGECGTPTCLAFAMNLASGKASLDSCPYVSDAAREALDAAAAPPIAKVVLGAGPTAVEMGDETELFRHDKRFYHETAIAIQVSDNLSSEELKAKVEAINGLNFDRVGQHYTIQAIAIRHDADDPAAFKAAVASVAAATQLNLVLMADDPDVLKEALAGVADRKPLLYAATGANYEAMTALAKENNCPLAVYGNGLEELAELVDKIVALGHKQLVLDPGARETSRAIADFTQIRRLAIKKRFRSFGYPIIALTTAANPLDEVLQAVNYVTKYASLVVLRTDAKEHLLPLLSWRQNLYTDPQVPIRVEEKLNEIGAVNENSPVYVTTNFSLTYYSVEGEIESTKIPSYLLSVDTDGLSVLTAYADGKFEAEKIAAVMKKVDLDNKVKRHRIIIPGAVAVLKGKLEDLTGWEVIVGPREASGIVAFARANLAS
The following text describes a protein:
Function:
In neurons, plays a role in the regulation of intracellular Ca(2+), possibly by acting as an activator of ATP2A2/SERCA2, thus increasing the efficiency with which Ca(2+) is removed from the cytoplasm (By similarity). Inhibits differentiation of embryonic stem cells into neurons and inhibits neurite outgrowth, likely as a result of its role in intracellular Ca(2+) regulation (By similarity). In pancreatic beta cells, lowers Ca(2+) levels in the endoplasmic reticulum and enhances glucose-stimulated insulin secretion.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Extracellular vesicle membrane; Single-pass membrane protein.
Sequence:
MVITSENDEDRGGQEKESKEESVLAMLGIIGTILNLIVIIFVYIYTTL
The following text describes a protein:
Function:
Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3). Involved in regulation of flowering time. Required for the expression of the flowering repressors and FLC and MADS-box genes of the MAF family. Involved in the control of seed dormancy and germination.
Subcellular Localization:
Nucleus.
Sequence:
MGDLENLLLEAAGRTNSAGRSRHPPSSRRREGSYSDGSSDSRDDSDEDRGYASRKPSGSQVPLKKRLEAEREDRAARVEGGYGDGPSDREGDSSEESDFGDDLYKNEEDRQKLAGMTEFQREMILSERADKKGDKNFTEKLRSKRESEKTPVSKKETQPLPASRGVRSSARSADRAAAKDDALNELRAKRMKQQDPAALRKLRDASKGGSGSRDFSSTKRKPLASSNLSSSSQSDSDSRSQSDDEGSNGGMLDSDDDRSDVPTFEDVKEVTIRRSKLAKWLMEPFFEELIVGCFVRVGIGRSKSGPIYRLCWVKNVDATDPDKTYKLENKTTHKYLNVVWGNETSAARWQMAMISDGHPLEEEYRQWIREVERTNGRMPTKQDISEKKEAIQRTNSFVYSAETVKQMLQEKKSASVRPMNVAAEKDRLRKELEIAQSKNDEAGVERIKSKIKQLDASRNKKGVDKKALKLAEMNKKNRAENFKNASEVKSITASLKAGEAGYDPFSRRWTRSSNYYNGKNKGKDGEENEAAVAAAVETNGADAGAGVEATEAALEAAAEAGKLIDTRAPIGQGAEHNQLHNFELSLSLTALQKYGGPQGVQKAFMARKQLTEATVGCRVAENDGKRHGLTLTVSDYKRRRGLL
The following text describes a protein:
Function:
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MASENIFLFVPNLIGYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARVLNQGTRFGAMLDMLTDRCSTMCLLVNLALLYPRATLLFQLSMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFNFSEGPLVGSVGLFRMGLWITAPIALLKSLISVIHLITAARNMAALDAADRAKRK
The following text describes a protein:
Function:
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
Subcellular Localization:
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Domain:
The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.
Sequence:
MSFDINWNKINEDSTINQRARAFLNEHLESLQLPSYVSNIKMTDFKLGTIPPRITLKQIDNPLDDFYEALRLEGASIGGRDTDVQFLMEVDYKGDMLIELSAELVLNYPSPNFMQLPVKLTISDIGIHSLCLVAYLQRQLFISFLCDVSDPALDNVESPLDSNGPAFLGSKAVERISLIRSIKIQTEIGPQDLSEGTILRSVGKLEQFLSDVFKNLLRKEAAWPSWINLDFNEDVSADVESSSSAEESLPHRDDAQDFSADARA
The following text describes a protein:
Function:
Involved in allosteric regulation of aspartate carbamoyltransferase.
Sequence:
MSENKQALQVAALKNGTVIDHIPSEKLFTVVQLLGVEQMKCNITIGFNLDSKKLGKKGIIKIADKFFCDEEINRISVVAPYVKLNIIRDYEVVEKKEVRMPDELHGIVKCANPKCITNNEPMPTLFHVIDKDNCIVKCHYCEKEQKREEITIL
The following text describes a protein:
Function:
Toxic component of a toxin-antitoxin (TA) system. An RNase.
Sequence:
MLALDTNILIALQKLEPAAFGHDRQALMTVPVVIPSVVRYEARRSLLAPQYARRLAQLDQLLSGHATLDFDQQAADIAADIYHQLCTTGQLIDEADLMIAALSIQHGAALVTRNTSHFQRIPGLTLLDWL
The following text describes a protein:
Function:
Required for the growth, maintenance, and/or stability, and thus infectivity, of bradyzoite cysts.
Subcellular Localization:
Secreted. Note=During the bradyzoite stage, secreted into the cyst lumen and localizes to the cyst wall.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MANTSVRRRQLLSSVLLLQWLTTVLGVAWGPNPIDGSKHGQFPSLRRTEGVSQSGSGHKGSVYRIPLADMTFWSWMSYLKELPDIDESRNPILKRLLSGSFLRRDGSTTVNVRVPARELVRLLSLTPEQQREGVSAKVRLINLLDPKYSVYEPYLYREILPKRSPLLLPSLGEYRGAFLTYIFHPLSKGLVGDMLETGRSHPDVQVLAANMVAALKSLHNLGLLHRSIELNSFSVLPDGTVVLGGLDTAAPIGTETRLWVGFFGQETAPEIDRNFLADLALTQGRHTVKSDVYSLGVAFRNLVQLLGNGNIGPEDRGAVRQDHLELLDKLSQKMIEEEPGNRPTIEEIMKDPLFEGLNFEDIEEGKARPFRYKQNRL
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MNVINEWEEMYQTGGLTPEVIVQHLRNIAGTFILPVGADQPQLPDQQQQEQHQQEQQNVPDPDAQGGNNGFLSGNYVYSDTMARAATIAVMELFICGPNPDNYLEQIRQADTVSSVCGRVFKIGEPTYSCRECSMDPTCVLCSTCFKKSEHRNHKYKMATSGGGGCCDCGDEEAWKKYPFCEEHAVCITDQTQASQQQQAPLPEERKMRCEIVFRAILNYSMQMLQMHGTGNCPELEDDENTHCTILYNDETHTFEQVIQTLTSIVKCEHKTAIEYVTSIDREGRAVVKCASFEVCKKLKEDIENKAMRSTLTTRAMPLKVTVMHRNEVACQHLAMQLLVWLQEFLTKNSTFRSVFAETISKPQVTYNLKFILSNDHNLWKSARACWHRLLISGMLMEYENKKLLATTFTKLYTSLMQDFIRDDHYHSFSIVSLSVQLFTVPTIAHYLIENESAFFKLMHTYFSETIDKYVKNRQLVFIKNTSTMNSFKRAAYILIDLKYLLSFKPEKWTPELRVGFLHGMQQLIRLLKYMQGMDAATRQVGQHLEYEQEWETAFTLHLKLSHLITLVLEWCATDRMVLLKVLRMVITALTETKFIALESETVVCEAANHSASCLTYDVLTRPVSVHLPLTRFLAGLYTVFERHDFTFDKVSQNLPDRPTPEQIIEPVLCARTMMSQVQAGMWRRNGYALINQLFFYRNVKCRYEMLDRDIVILQMGASLIEANEFIIHVLNKYKLLGWLEQDVPERQRAVDAGSGSDEDHMRQAGILVEEFLELLIVIIGERYVPGVGDVTESDRIKKEIVQQLCIKPHSHSELSRALNEDSCSEIMFESVIDEVAVFEKPNSAEKRGVYILKPEYNSWYNLYFYHYSKEDKSRSEERQRLQKKEKNELVCCPPPTLPKLTQIFSTIPTLLQCDVMLKVMHVVMTRALDLRSVSFTEGQLQRVLHLIGYALQEEESGHYPYMNFLRPKPNDRAAADAGGALQPSKGGIAAGSAALGNSALQSDGGEAHQLDPERDRSGRVERQRAGDGRPGPPREGAAGEAGGVAPGPADGADEAGAANVHDHQPGHVQHRERRFVRAGPDGAGAERRHGLADDERAPGRARPEPYAGQAGRHGRPAPLVHPLLGKVRPRHVPLGQHGVRRVRAAVERAVPLPADGRAGPAAADRDEDAPVAAPDHLRARDAHDLLRQVLQQRGDQGEPAPVPEPGPDPVRHREERVPVPAVPLPEQLSAAAGAAARNDHEQREGAHERVGAGGRRPRLAARSADNAAERVHLSAVVRVHAGHGGKHGAPRGASHTAAWLVRRRHAQGACDPRHAAGCADQALPGGGTAADEP
The following text describes a protein:
Function:
Transcriptional regulator.
Subcellular Localization:
Nucleus.
Sequence:
MHCSCLAEGIPANPGNWISGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFSKLIVVNYPLWEVRAPPSPHLLLGAPALCRPALVPVGVQSELLHSMLFAHQAMVEQLTGQQTPRGPPETSGDKKGSSSSVYRLGSAPGPCRLGLCCHLGSVQGELPGVASFTPPLPPPLPSNWTCLSGPFLPPLPSEQQLPGAFKPDILLPGPRSLPGAWHFPGLPLLAGLGQGAGERLWLLSLRPEGLEVKPAPMMEAKGGLDPREVFCPETRRLKTGEESLTSPNLENLKAVWPLDPP
The following text describes a protein:
Function:
Protein phosphatase which antagonizes mitotic cyclin-dependent kinase CDC28, the inactivation of which is essential for exit from mitosis. To access its substrates, is released from nucleolar sequestration during mitosis. Plays an essential in coordinating the nuclear division cycle with cytokinesis through the cytokinesis checkpoint. Involved in chromosome segregation, where it is required for meiosis I spindle dissambly as well as for establishing two consecutive chromosome segregation phases (By similarity). Plays a role in the expression of hydrolase genes such as CHT3 and ENG1 involved in septum degradation after cytokinesis. Also required for ACE2 localization to the daughter nucleus. Required for invasive and hyphal growth.
Subcellular Localization:
Nucleus, nucleolus. Cytoplasm. Bud neck. Cytoplasm, cytoskeleton, spindle pole. Cell septum. Note=Does not accumulate in the nucleolus in interphase cells. At the G1-S transition, starts to accumulate both in the nucleolus and the and the DAPI-staining region of the nucleus. At the S-G2 transition, starts to concentrate as faint foci on the nuclear periphery. In early mitosis, the CDC14 nuclear signal diminishes concentrates to the spindle pole body (SPB). During cytokinesis, the localization at the SPBs gets fainter and the protein is preferentially found at the septum region. In yeast forms, in which cell separation takes place after cytokinesis, CDC14 is present at the bud neck; in hyphal forms, in which cell separation is inhibited, no CDC14 signal is detected.
Sequence:
MHSSSVHVPLIEFLKNRIYLGAYDHHKRDTEDLAYFTVEDALPYNAFYMDFGPLNIGHLYRFAVLLHKKLNEDSTQGKGLVIYSSTSPKERANLACLLCCYMILLQNWAPHQVLQPIAQITPPLQAFRDAGYSSADYEITIQDVVYAMWRAKERGMIDLAKFDLDEYEQYERVDQGDFNVISKDFIAFASPQQSKRGGLNEPFQKVLEYFVENNVQLVVRLNSHLYDAKEFTKRNIKHIDMIFDDGTCPTLEYVQKFIGAAECIINKGGKIAVHCKAGLGRTGCLIGAHLIYTHGFTANECIAYMRMIRPGMVVGPQQHWLYLHHDDFRSWRHTMIVDNRPDPLIGNLFPLCSYEDYKQRLKEAKRKERLQLQQQLTSPLADSSVINTPIRRRKVSGALASKIQTVVPIESPGQPRKYFEDSEDIDEVEMVNNSDDENTMQDIIQSSPARYDSVTPKTKDNSDWRVLRSISTNNVSSQQSIHIIKTTTTKTVNETLSSPPGTSPTNVLRVSKARSKNRIASGNSQTSRAHSGGVRKLSGKKH
The following text describes a protein:
Function:
Seed storage protein.
Subcellular Localization:
Secreted.
Sequence:
MASASDKLVLSAIVLAVLAAVVAAASGYGDVGEYCRVGKAVSRNPVPSCRNYIARWCAAAGGRMDSRKQPPREFLEPCCRELAAVPMQCRCDALSVLVRGVVTEEGDRVSGMISQHAAPGCDAATIAGMASALTDYGRCNLQHTAGSFACLMFGGGMD
The following text describes a protein:
Function:
Sterol O-acyltransferase that catalyzes the formation of stery esters.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MATSTSTMTNPTIATAIDMPPRPVNRRGTGTQASQPSTSGTTNGTTNGTIQNTRNPPRDTKYRHVFATHSLRRTSCLSSDSESSPSFKGFRNLMILVLLVSNLRLMIVNLQKYGVLICISCHDYRRSDIVTGLLLYLLVPAHLFVTYLIELVASWQAKRAYARISKEDDDDTPERYAAALKSFNSIWYIVAFCHSINATMNLYIATKFVYYDIYHPGIGTMCELHAIIVFLKCASYAFTNRDLRHAYLHPRQADPLPELYKSCPYPQNINFKNLCYFWWAPTLVYQPVYPRTDKIRWGFVFKRLFELAGLSIVVWIASAQYAAPLLQNSLDKILTLNFTSIAERTMKLSTISVFCWLCGFFALFQSALNALAEIMRFGDREFYGDWWNVSSIRAYWTTWNKPVTNFMRRHIYSPLVGRGCPPALAQIIVFFFSGILHELLVGVPTHNIIGVAFAGMMIQIPLVALTDAVRKIKWIQGEVAGNMIFWMSFCLVGQPLAALLYFFAWQAKYGSVSRQFNQEPSALSMLLKR
The following text describes a protein:
Function:
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
Sequence:
MELEESGIREECGVFGCIASGDWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPKFRVHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAPAAYSLVIMHRDVIYAVRDPYGNRPLCIGRLMPVSDINDKEKKSSETEGWVVSSESCSFLSIGARYCHEVKPGEIVEISRHGVRTLDIIPRSNGDPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCGQQLAVEAPVEADLVSTVPESATPAALGYATKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLIDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKHPCFMGINIPTKEELIANKPEFEYLAEYLGANSVVYLSVEGLVSSVQQEIKFKKQKVKKRDITIQENGNGLEYFEKTGHCTACLTGQYPVDLEW
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MAMAGRGRGRGRGQMSFNVEAMGLGKGEPLPPSTLQPTPLFPPMENKPVPLQAGEEAEYMLALKQELRGAMKNLPYFVRPAVPKKDVERYSDKYQSSEPTDNTIEWTPDWNRLPRELRIRVRKPPKETVKRKVKEPLQVPKRSQQKRVDKEEIIRKLEVRTVQTLEKKEQEVSSEEEEEEKKQEEEEQENEEEYDEEEFEEETDYVMSYFDNGEEFGADSDDNMDEAIY
The following text describes a protein:
Function:
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
Sequence:
MDFRSLIASSVAQDKDREFEVRPSSRGSWSCKEVDEFDALSIEYEPKPIEKYPAKLHARQVKKYLGLQEGLIYLPGLPSFNYEDSDMQPAFRQRRYFYYLTGVNFPDCIVTYSIHRDQLWLWIPPPNSGRSVIYNGSRPTAKEIMAKYDLDHVETLPHLDSYLTWYAHTEPGKIHVLHDYQTPNNVELQITRKNGSQSIMSESPFDSTKLEEAMNTARAIKSPYELKMIRKASAITAQGHINVLRGLRYLSNEAEIEAIFTATCIARQAKTQAYGVIAGSGENASTLHYMANNEPLKGRQLLCLDAGCEWDCYASDVTRTVPISGEYTEEAQAIYDLVAKMQDECIEMLKPGANYRDVHMHAHKVALRGLMELGLVEGGTFNELYMAGVSVAFFPHGLGHYVGLEVHDVGPGGMIITNRLFDFNRKPADWTDAYFQILSDSGINSGGGAILSKDMVVTVEPGIYFSRYALEEVYLKSPKYAKYINKELLQKYYPVGGVRIEDDLLITEDGYENLTTAPKGEAALKIINEGREQEEKRVVCEKAAESKRKQKKTWFW