lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Sequence:
MTERRVPFSLLRSPSWDPFRDWYPAHSRLFDQAFGLPRLPEEWAQWFGHSGWPGYVRPIPPAVEGPAAAAAAAAPAYSRALSRQLSSGVSEIRQTADRWRVSLDVNHFAPEELTVKTKDGVVEITGKHEERQDEHGYISRRLTPKYTLPPGVDPTLVSSSLSPEGTLTVEAPMPKPATQSAEITIPVTFEARAQIGGPEAGKSEQSGAK
The following text describes a protein:
Function:
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
Sequence:
MSRRRAIQPSPALRIGPIELASPVVLAPMAGVTNVAFRALCRQLEQSKVGTVSGLYVCEMVTARALIERHPVTMHMTTFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHIDMNFGCPVPKVTKRGGGAALPFKRRLFGQIVAAAVRATEGTDIPVTVKFRIGIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIARLKQHVRTIPVLGNGDIYDAGDALAMMSTTGCDGVVIGRGCLGRPWLFAELSAAFTGSPAPTPPTLGEVADIIRRHGTLLAAHFGEDKGMRDIRKHIAWYLHGFPAGSALRRALAMVKTFDELDCLLDRLDGTVPFPDSATGARGRQGSPARVALPDGWLTDPDDCRVPEGADAMGSGG
The following text describes a protein:
Function:
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MADLAASGELNQPILNLTPDEKRIFQFLFQQADTEKLGVITGEIAVKFFERTKLAPAVLGEIWQIADTENRGLLTMAGFCQVLRLIGHYQAGRDPAPELAFRPAPLPKFEGLNIPAAPSAAPSFSPQATGSIQPQMSGNGPIRVPPLVPAKAAEYAGLFEKSGAVNGVLSGENAKEIFEKARLPNEVLGRIWNLSDTEQRGALNVTEFIIAMHLLASYRTGNMKALPNALPPGLYEAASRRGQLPPPPGRPDQSTIPRQFSGQNAPRQGSPLARPPFGAPPPAAQPTGSDWLISPQEKSSYDNLFKGVDTTGRGFITGDQAVRFFSDSGLPEDVLAGIWDLADINSEGQLSRDEFSVAMYLIRQQRKGDALPTTLPPSLIPPSLRTAANQAVPVPAQAAPPAPQPKSAADDLFGLDAFTAPTAAPAQAPQSTGGSASFSRPFDNDPFAKQGSVAYFASSVPTFSTKPCFHIQAFHAELFIWPDPHITFYCRAPPSAMDDLLGGETDAEINKKLTQDSTELANMSNQMTTLRTQMQEVSNKKVTTASDLNSVNTQKRDLEIRLTQFKNQYEQEVKAVKELEERLASSRNETRKLQQDLAMIEGTIQDLQNQHRQVGGALEADQRENSNLKERIRQINVEIGQLRPQLDKMRNEARQQKGMVAINKKQLTTNEGEREKLKSEINELSRAPEDGVRSPQAQTPSVVSPAASVTSQSTNPFFRKSPAPVTENTMSPSGFARDGPHKDFDSVFGAFGPPQSAAPSVSFRPDSQNQGAFSAPSGQSVRSSEGPDVPTPSTSPPLSSYQESPRGAEPPAPPESRQFASAFLPLRDAVPRSDSFSSSVKVSAPGSRHGVPGTETPTISKASPASTPVAEKPSIERADTSRTETDNFNPSLFDRTFSTASPVASVTSDAQRSTRPEERNNYPSFGPPSQVTQDLPGAFPRDTASPLQQMQTGESNLSGASKNTNRADPFGSASGEQPRVGGKVDFDAAFAGFGPNRQNSASVSSNGPIDNSNRFNKEFPPIEDLAHDDDSDSNDGRGFDDNFTSASPHQKRTSAGPDAVSQPARPGTASTTDDLYSRPAPASRLDSTLSDLPTPGAQKSPPSYESTVPQRSGSNQFPPEFGGLLPSRDVPGSPTTSQGPEKSYNPSGGHGAALFGGPQSKSVTTSPPPLDTPSSTVPSDAYHSAVSYGTSETNKGPTPPANVPQLGRSAFNDDFDAGFDDLTEAKEDDKTDDDFMFSSQRSDGLDEFNPVFDSPAASKSNTMASQQTPTGKQRADDSFSDFEHLSQHFGQPQAPQPSSSNQDWDAIFSNLESSSTDKNSQQASTEFGKSSVFDTLDKEEAAASSSLAPQMPQLGRAISTGTEHDDPILKKLTGMGYARNDALDALEKFDYDINKVS
The following text describes a protein:
Function:
Acts as a component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Golgi apparatus membrane; Peripheral membrane protein. Note=Localizes at the barrier septum.
Sequence:
MDVKSKHGHIKSNPEESLLFRNSVSKNIAQLSSINYADRNVQAALEQLSERKFKNEREARKQLPFEVFSDLIWTNGSIIKELSELSSQTLSVQSQLLKVKNSIDSYKNEWSKKTNDAQILLNSYETFCEEEALIEEKLKNIEIFEKNFVIMDDDLIHLTSSTDVDDRFYLILDKAQEIHDSSDSLFASLSGFVEYSSFEEIVKKMSRYIEAAFEKLFRCVQTELSDPQTAQTLEANSHLKKAFTKLFSEPTMVNKSINLIVQARQQILSTAYLTALTRGDFLSSSRPIELSAPDTVRFIGDLLAWIHQTIVNEKELVEALFAARKRQIQLNPFPPWDVPNVLEDQMNSLLDGSLYGICRPLSSRAQTSVLDLSDIVRLYNVIEILGFYREAFSKIVHDECIILRIIKTLEDFTYQRMKTVLDDELYTISNTNLSITDDLLPPDFVTTFLRNANSIFKIRGASLSVQGVDELPFKMLFMQLFDRILEICAAMTEDVRPPYKGIILMLNVLDSCTNYVGRYTFLNELFEYLQEKTTYYKNNLTTLLNNDYIAQAGLSDLLQKIADTTDDKQALKNYLHSWKWDQQIDKFSTFIRKTLSETIDNLQLLTSPIVTNQVLKETAISFVGAIETVDKALELSNLERRWPLSTEELLIAMNVDSMDTLSDIGQSDIDNLSVN
The following text describes a protein:
Function:
Constant region of T cell receptor (TR) delta chain that participates in the antigen recognition. Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1. Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair. Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT. This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells. Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes. The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames. The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements.
Subcellular Localization:
Cell membrane.
Sequence:
SQPHTKPSVFVMKNGTNVACLVKEFYPKDIRINLVSSKKITEFDPAIVISPSGKYNAVKLGKYEDSNSVTCSVQHDNKTVHSTDFEVKTDSTDHVKPKETENTKQPSKSCHKPKAIVHTEKVNMMSLTVLGLRMLFAKTVAVNFLLTAKLFFL
The following text describes a protein:
Function:
Acts both as a repressor and an ctivator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3'. By controlling the expression of genes involved in cell differentiation inhibits the lineage commitment of multipotent cells. Prevents, for instance, the differentiation of multipotent mesenchymal cells into adipocyte and osteoblast.
Subcellular Localization:
Nucleus.
Sequence:
MHCEVAEALSDKRPKEAPGAPGQGRGPVSLGAHMAFRIAVSGGGCGDGNPLDLLPRLPVPPPRAHDLLRPRSPRDYGVSKTGSGKVNGSYGHSSEKSLLDLDLAEGPSPSCHQGLFLPAGTPPPRGHPPVCEKLLHFPHPNRSPRPQATFVNGSLPAAQHIKQEALPDYQAMVSAHTPLPTHCRAPSSMGLPSDLDFPDRGLTNPAPSCYLLGNEPISDLGPQPEAHLPEGSLKRCCLLGLPPTSSASSSPCASSDINPVIHSSQTALVSCVNGLRSPPLPGDLGGPPKRSRPGPASSDGQEGSLQLEACRKSGFLKQEPMDEFSELFAPHHQGLPPPYPLPQLPTGPGLGGLGLGLAGRMVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHTGADPEADVLSECLSLQQLQASTLLPASRGKGSQTLSQELLPGVYPGSVTPQNGLASGILSPSHDVPSRHHPLEVPTGSHHHLSPLPTAESTRDGLGPSLLSPMVSPLKGLGPPPLPPASQSQSPGGQSFSTVPSKPTYPSFQSPPPLPSPQGYQGSFHSIQNCFPYADCYRATEPAASRDGLVGDAHGFNPLRPSTYSSLSTPLSAPGYETLAETPCPPALQPQPAEDLVPSGPEDCGFFPNGAFDHCLSHIPSIYTDT
The following text describes a protein:
Function:
Probable E3 ubiquitin-protein ligase which is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit from mitosis if spindle function is compromised. Inhibits the septation initiation netwok (SIN) during spindle checkpoint activation. The effect appears to be mediated through preventing the SIN activator, plo1 kinase, from localizing to the SPB.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Also localizes at the division site in mitosis.
Domain:
The FHA domain is required for the proper localization at the SPB.
Sequence:
MTKSVEGYLKEQELAAETDSEKDDDKISIRLTNFVGPNAHSFSFDPLVRYWNRKQNNLPIYIGRYTERYNGGDVSAIVFRSKVVSRRHAQIFYENNTWYIQDMGSSSGTFLNHVRLSPPSKTSKPYPISNNDILQLGADYRGGHEVNYRCVRARVELNNSWKIKLSPYNLNEFKRMQELVLCGSSESGPPECCICLMPVLPCQALFVAPCSHSYHYKCIRPTLNESHPYFSCFICRKYHDLEAPVEEGDESLNDLLRNATVKDDASE
The following text describes a protein:
Function:
Plays a positive role in the antiviral innate immune signaling pathway. Mechanistically, interacts with MAVS and functions as a positive regulator to promote 'Lys-63'-linked polyubiquitination of MAVS and thus strengthens the interaction between MAVS and TRAF2 (By similarity). Also plays a role in axon and dendrite arborization during cranial nerve development. May also be important for neural crest migration and early development of other anterior structures including eye, brain and cranial cartilage.
Subcellular Localization:
Cytoplasmic vesicle. Cell projection, axon. Cell projection, dendrite. Note=In developing neurons, accumulates in early growth cones and at branching points of axons and dendrites.
Sequence:
MATASGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFFSYLHLPKKDGKTAKRAPRNEPDYTTLYYREHPRAGDFSKTSLPERGRFDKCRIRPSVFKPPVSTGKGFLSMQSLAAHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEGGPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHINHLGGSLDRASRSPKESGPLAVLSCLPEPPPPYEFSCPTTEEVAVLPDTCEELKRDLGDQDVSNPFTQVLEERQRLWLSELKRLYVDRLHEVAQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRTSGPPMEADPNARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELARLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGNEAREGAEQLRAELLQERLRGQEQALRFEQERQTWQEEKERVLRYQREIQGSYMDMYRRNQALEQELRVLREPPTSWSPRLESSKI
The following text describes a protein:
Function:
Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.
Sequence:
MIFGKNIGQLVSRLAQGSAYNTHGLALCATQSSSISQTLLPVMNHFMVFSANLSTASETTQKKMPVDSTSAPNALLSTLNNAADNSVILPAAFIDSPGKKDADISTQAGKNLLRILQSSPKNKWDDISSSYMDMKKSNMLAKLEPSEWIDIINEFSRLSAVQNKADVFPTLWEGIKKFNVELTPKLYSALVTSVFKHDASLVSTQQLQQSRLDQEKLYAKHSKSIDRSIAIRSLTRKIMQLKSTSVFSLGCEIFESATTANIRMSLYAYNAFIQSCALRGETLMAEDAYSGMINAGHSATTETYTSMINVYGIAGDAFNAQVWFEKYIELSQTPETMPFLAFSSALAICGRLPAAIDVLVRLMPSAMKSVSIKSINELLSLLDQRLDFEGMQLLYDTLNKSPELPNPSPKTYSLMMNAALINGNLNEALGYYSRTEISYLPPYCIGLLGSTSADIGDLDLSLKLAKELLSRNQIPEISHVVGLVQGLYNTDPTGARSMEFLKIIISKFINRSGNIAPSASIDRGLTALITCTATNSNIRCALDAFLFAEAAKVYLSQPFAFAICMTFKKATPDAIAQLTAVDYHALFDCAFSHHNPRSEISSQIAVRLFVKKVFSSMILHKLEPTQQIHETVCKGFDNIRDSMGKAEWLVLVRPYNFDTIPSAALDVEKKTSSILKQWRQPTAPPVESTHNDESKSMIAQLEMHCATFEIKEALSLFKRISDAGQKISLSVLQSLMNSLAKSKDHASIREVIDISTALAQTYNTELAIQRAQTAIYELAISAYLNARDPVMALEMTVEAVKKYGKIPKIGVCLALFKRFDRFENISVTLAKHCTDLFQPLIAECGVTNLTPDVFSYMFRVHCITNNIVEAKSLLDLMKKHNLHVSGKSLEHLVHLYVKADLQADSLDAFDQYLDMTPVLSISVFNDILKMYIKNSKDITGAMGIWRVSRQRNVAPDANTLIWLLSGLVDLSNDVGSAKKLFDALTLPAGAPGSAGFAIQPSIIHYDILLSGYARAEQPDMDAILELYEDIQQKKCSPTVMTFENVISGVCRAADGSIRIAEQIRNLMFTHKFSSTPEIENSIMELYWKLGDQVGAFQIFDRLTTEQDADLQPNIRSYQIMITGLVKCGQRERAAALLDRARRHGGYPQTAVDELEQIILQ
The following text describes a protein:
Function:
Transcription regulator complex subunit that is essential for cell cycle progression.
Subcellular Localization:
Nucleus.
Sequence:
MGDPTNNNDSETKPNPATYWKSRFPVARIKKIMQADQDVGKVAQVTPVIMSKALELFMQSIIQESCKQTRLHQAKRVTVSHLKHAVQSVEQFDFLQDIVEKVPDAPPIKAERKTKRPRARRAANEGEHNESVPAKKVKKNTVKEEEIEKDDESATTETPVKEEPTGEETEADHEEKASVDHGNFSDKTTSEASSASGDE
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MFVCPCRKHHLYTHLYFSHFRQIVKRKSAENYNGTPYVATLLSCSLWILYGSLDPDDGLLIVTVNTAGATMQALYLVLLLIYTTKEKRVQYFGFVILDIVFFGIVLAFTLVAFKESSRRTFTGVLCATFTTIMYVAPLAALRTTIKTKSVEYMPILLVSSLFLNGCVWLTFALLVTDIFVLVPNALGILLGTIQFLVYLKFKNSTPEAGELGKGSYEKQIETSVIDIQDSNVKSNNVSTQNRTLTRLDAFPVIRSPSLSPNRSPSNQQHEDDTEQWCELKV
The following text describes a protein:
Function:
The Nudix hydrolase domain is active on ADP-ribose, (2')-phospho-ADP-ribose, IDP-ribose and NADPH.
Subcellular Localization:
Cytoplasm.
Sequence:
MQTKYQYGIYIGRFQPFHLGHLRTLNLALEKAEQVIIILGSHRVAADTRNPWRSPERMAMIEACLSPQILKRVHFLTVRDWLYSDNLWLAAVQQQVLKITGGSNSVVVLGHRKDASSYYLNLFPQWDYLETGHYPDFSSTAIRGAYFEGKEGDYLDKVPPAIADYLQTFQKSERYIALCDEYQFLQAYKQAWATAPYAPTFITTDAVVVQAGHVLMVRRQAKPGLGLIALPGGFIKQNETLVEGMLRELKEETRLKVPLPVLRGSIVDSHVFDAPGRSLRGRTITHAYFIQLPGGELPAVKGGDDAQKAWWMSLADLYAQEEQIYEDHFQIIQHFVSKV
The following text describes a protein:
Function:
Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development.
Subcellular Localization:
Cell junction, tight junction.
Sequence:
MSSSYWSETSSSSCGTQQLPEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPFNSREVLSPLKTTSSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNTEQELHSPTVKLTTYPQTTIRKYVVQNPEQEPLSQFLRGSHFFPGNNVIYEKTIRKVEKLNTDQGCHPQAQCHHHIIQQPQVIHSAHWQQPDSSQQIQAITGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSTGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDKYTCP
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MNSFVSRLVIFLLIGDMALASDMYSSVAELERLYLKEQQAGLKLESLLDLIKKQTTAIDQYLSELTEIRSANLDSRGVISNPINAFHMMRRLTIGWREVKTTLETHGNVTDIVQDVFKISKSFPNDEDLSGAAFSLAQLQGAYRLNVSQLASGNVQLSDRISFPSVRGLNARDCLFIGKHAFNKGLYGQAVDWISTAAEVARSENNRSASVSEIKPFLSTAIRVHDDVLEKKGPIGADWRTNPEPFERRAKSLRRARRSQEQQQQQTQRMRDITYTPLGAGHGLATNKSPEWSEWEELEVFFRLCREGEEKSRPTGLKGRLKCRQISHTHPYFILRPLKLEEHSLVPYIAVFHDFMSDAETEIFKSLAMAERLERSAHGSKRPGQGGVTSDKRTSKQSWVEDGSHHVVDQISKRISDSVGLNSQPSNVGSEHYQVANYGIGGRYTPHTDHGVLSKSMGGPSEFDLFRGDRILTFMTYLDDVEAGGATVFTHAGVVVRPKKGMAVFWWNLKSDSNGDTLTRHGGCPVLHGSKWICNKWFHSGEQFLKRPCAKKPRSRISYPGTTSSRLLNN
The following text describes a protein:
Function:
Catalyses the transfer of galactose onto proteins or lipids.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MKLQIPAVMRSRAAEMTSQFWLVMSHIWDTMSDGRVVGRAFFWYIWIMVVMATVSTLALWASLDASYGHPGVVHRYAREAEEGSGLMDSLRRLSYQIDGAFTRPRTVDVKARKLIHGPVCPEIDIPGSEKNLTHELNETTMFHVEERVLHTHTMDARRLTQHSNEKLQKLYQARKINTASGAGIPDVLNDGLETEEYILLPGGHWIPTKCSPRWKVAIVIPFRDRHQHLPILLLHLVPFLKSQYLEFSIFVIEQENDLRFNRAMLMNVGFVEALNYTMFDCFIFHDVDHIPLNYGNLYGCSGMPRHFVSGVDRWNYKLLYGAFFGAVTGFTRTQIEKFNGFPNAYWGWGGEDDDILGRIRAKGLSKTRPWGPVGFYNVIPHHHKSAKKNMDRVCLLNHYKERMETDGLSNLYYGTPSVQLYPLYTNIGVDIQDLPWNVAWHVCDRDAELFEKILREKDVVAGEGHILEIQKEDVKKPKEESPKG
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.
Subcellular Localization:
Nucleus.
Sequence:
MDSDDWGLGAIVRSCAGAGVDAEATTPAPVASRGRGVASMELVGRPVSAPAPSMTTASSSSLHDVLEYLDLHHEQQLPRAPFSITPSTAMSREQRAPSELVSLFSAASTSSGQLTPATKKPQQGGGRKPGGRAHRPKRSKISRKSQVKKVVREVPLVADGVISGDADDLWAWRKYGQKPIKGSPYPRGYYKCSSLKACAARKLVERSPDKPEVLIVTYIADHCHAVPTLVNALAGTTVCQSTSDEATGAARREDSVDGSSSVAADEASSELRSPVEMELDDFFGLFDEDLDSFFGDGDGDDVLGRRVSL
The following text describes a protein:
Function:
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
Subcellular Localization:
Cytoplasm.
Sequence:
MPKVGVYVCHCGKNIAGKVDVQRVAAEMKKHPQVTVSRHYFFMCSSFGQELIKRDIKAGKVDRVVVAACSPKLHEPLFRGVVEEAGLNFGYYEQANIRELVSWSTEDPEEATRKAIAYTWAAVERVLEAEPVESEEFRVNREALIIGGGVAGIAAALDLAEKGIRVHIIERSPTIGGKMALLDRVFPTGDCSLCILTPMMAEAEHNPNITIHTMCEVTEVSGSVGDFRVRVKKRARYVDQDKCVACGICAESCPVEVLNEWYARLGKRKAAYIPFPQSVPRAYVIDRENCLFFRDGSCRKCEEVCPAKAIDLSESDGEFELRVGAIIVATGADEYDASNLKNYGYGKIADVITHFGFESLINVNGPTGGHLRRPSDGKVPESILFVQCAGSRDVNNNPYCSNVCCMITLKHAEIIRMEYPETKVYVAYIDMRTPKKGFEEMYARVREEGVVFIRGKPGEIRREGDKLVTEIYDEVLGEKLRLEVDMVVLAAGLSPSEGTLSISRTLNIPRDLYGFLQELHPKLKPVQTSRPGIFICGTAQGPKDIPDSVTQAKAAASEAARLLMIGKVLVTGEKAKVNSELCTGCGACVEECPFSAIVLEEGKAKVLPLACMGCGICQGACPTGAIERRLYDHGQILNQIDGLLEVVT
The following text describes a protein:
Function:
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.
Sequence:
MASSGAHLGFSTSKLLLIFTLSIGVKAVLYEPTGDVFVLDDSNFANNVFNSDKIWFVEFFSSWCGHCINFAPTWKSFAKDLLDWRHVVNVAAIDCSNKKNTEVCRKHDVHGYPSLKCFFPFTKPENMTGVKLHRGGRDVRALREYVAAQIEEEAQKPHRLKPWPDLQPAEAPWVSDFFTHHPNHQFLVIIFQGTDNFMGKEIILDVSNIEKVEARWMRKADNPLIEKWGVDSFPSAYILDRSGAPTKIVGTDRGSFSAAIKQHIKDNANKQPPVEQILDDTNHYHGDEMLKKEHLLGPGGVVGKVIKSEGDNIESDFDGRDVDEDGNLEIKEKEKEEEEKKNEMGLSLLLRPGDKGFVEMNKGGRGENDGGNAGEEEEGQGGGAEAGREKEAEGVGILREEVGGAGVGLDDVGVDEGLVGDEGEAGEEGGEGGGKQKMMWNKVLEKNKEKALQKKTNVRMSDQRPSEWPKVYMLDLESAIQYSLRQEVSLRSHIEGEELQALTNYVGVLSKYFPGRPEVMSFLSTIHQWLLEKEGTSIPIQEWLTLVDPTKEPGIGLPDRVEWIGCRGSEPQFRGYPCGLWTLFHTLTVSQASLIRRYDNVSYMEVLHAMRGYILAFFSCQNCRENFRHEVADLDDSITSLDSAIMWLWQTHNHVNKRLHGDPSEDPTHPKQPFPSRTICASCYASTNVELWEERRVLRFLKDYYGLRNFAFKGIHASNSGAADDTDMGTRATLNPEGVKQDVLNHLRQREMSIRLAVGTRRAGYFGLGINGVDLSMCMVLNVSCVMLIVCVYFVLVWRRRRRKRLLPR
The following text describes a protein:
Function:
Plays a role in cell growth. Hydrolyzes membrane phospholipids, such as PtdCho (phosphatidylcholine), producing the free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own). Involved in the inhibition of actin-based motility and endocytosis. Its inhibition causes complete collapse of F-actin organization. Plays an important role in cell migration by localizing along the anterior cell membrane. Overexpression leads to the inability to aggregate even at higher cell density. Also known as a negative regulator of quorum sensing.
Subcellular Localization:
Cytoplasmic vesicle. Cytoplasm, cell cortex. Note=In migrating cells, localized at the protruding regions of pseudopodia.
Sequence:
MNLSQEHAINQNLHKNQKNEEKIEKKTINKDGRGQMNYDGEEGQGEKSRFQKMVENEKIEEPQQKDENIPNTDVIERKEVGVIERINSEDVPILMTDNATDYKVLQHNLKKGKVSKKSKEQIEQISKQEENDMLEYLKNYKSNEEFTIQLEDLLSFETYFSRDELHLLYREFKTISKSGMFMSKEDFISKLTPFSRNADLTISLMNAIDRNGDQKIAFPEFVQALSIMCRGTKKERLRFTFEICDFNGDSLVSRDEVYSTVKAISDIFSKFGYSKDKFGDPSEAVDSIFSSGLTTNGIYLHNKKELTLNEFLERGELNPDLSKCFGMFDYFYLKFIGQIDLLFKDKEINMNGQLTKIKPKTIFNFNISHRRTLSLRDGFLIVYKKKKFKHDEDKPSKVIFLPGSTVKVVVGSQPSKKKKFLSKKFHNYYGFRVTKGNYNRFFLMENRDEALNWVNAIRFHSRQGFRFQSFSKVRSNISVEWFINGSSYYNELAETIRRAKHEIFITGWWVSPYVYLQRDNGIENMEKSRLDRILTEKAKEGVKVYVLMWNETNLGVQLGSRHAKNWLEGCHSNIHVIRHPKRYPLSWSHHQKNAIIDQQIAFVGGIDICLMRYETSKFQLTDDQGKRFPGKDYGNLLGTVIRTGDPKKDQFNRRECPRMPWHDVHTKIVGPSAKDVASNFIQRWNHAIYVERSNRFQPILVPKNYTGLPSDDAKPDKWKNLVSNIRKGFSHVSYGREKPTHYQRAGDNPKVRSHTRQGAFGLQSDQIDNKIDKQKNNSTNSENSENSYSEFDEEDEEGNQEEEDEDEFDEFEKDENQKQENSKIPFNNKPSDAGGLKSKNYKNNNNNNIIESLKDEESFELPGTPKIDLNNDKLLKSIYHLSSNMSENSCVVQMVRSICPWSAGTDVEDSCYKAYLGLIKNAQHFIYIQNLFFISSCGSKLPKNRIALAILNRVRRAITLKEKFRVIIMVPISPSGDLALASSRMIIGWTNRTISQGGQSILELLKNEFPDVDLDQYISFNSIRQWEANGDRIFTEQIYVHSKVLIVDDRVAVIGSCNINDRSMMGSRDSELAVVVSDQSKLLITMNGKPFKVGKFPHTLRVGLWKTHLNLTDSEISSIIDPITDNAFINIWRKTARNNSIIYKEVFGDCILENQRRLGIVQKKYIPKTNELIVQLSQIQGVLIEYPLDMFCESNLFNEQVGIFTAESYVDVSIFT
The following text describes a protein:
Function:
During the asexual blood stage, catalyzes the cleavage of denatured host hemoglobin (Hb) or globins. Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).
Subcellular Localization:
Membrane; Single-pass type II membrane protein. Vacuole lumen. Note=In trophozoites, localizes to the digestive (or food) vacuole, an acidic vacuole where host hemoglobin is digested.
Sequence:
MALTVKEEEFSNTLIKNASAFDRLKLGNLKNLKIQKKLQFLYLILFVLITGVFFFFLIGNFYSHRKLYQVIKNTKHTTIGFKIDRPHDKVLSSVLKNKLSTYVKESFKFFKSGYAQKGYLGSENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGCSTKHLYDASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIEVTDADDLEPIYSGSEFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHVGYLTIGGIESDFYEGPLTYEKLNHDLYWQIDLDIHFGKYVMQKANAVVDSGTSTITAPTSFLNKFFTDMNVIKVPFLPLYVTTCDNDDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALCMLYILPVDIDDNTFILGDPFMRKYFTVFDYEKESVGFAVAKNL
The following text describes a protein:
Function:
Binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat. It recognizes the 5'-TCCACCCC-3' sequence as a core motif and exerts a strong repressive effect on HTLV-I LTR-mediated expression.
Subcellular Localization:
Nucleus.
Sequence:
MQFVSTRPQPQQLGIQGLGLDSGSWSWAQALPPEEVCHQEPALRGEMAEGMPPMQAQEWDMDARRPMPFQFPPFPDRAPVFPDRMMREPQLPTAEISLWTVVAAIQAVERKVDAQASQLLNLEGRTGTAEKKLADCEKTAVEFGNHMESKWAVLGTLLQEYGLLQRRLENLENLLRNRNFWVLRLPPGSKGEAPKVPVTFVDIAVYFSEDEWKNLDEWQKELYNNLVKENYKTLMSLDAEGSVPKPDAPVQAEPREEPCVWEQRHPEEREIPMDPEAGAEPLVPAQDASSQVKREDTLCVRGQRGLEERAIPTESITDSPISAQDLLSRIKQEEHQCVWDQQDLADRDIPTDPNSESLISAHDILSWIKQEEQPYPWGPRDSMDGELGLDSGPSDSLLMVKNPPPAPPQPQPQPQPPQPQLQSQPQPQSLPPIAVAENPGGPPSRGLLDDGFQVLPGERGSGEAPPGGDRSTGGGGGDGGGGGGGAEAGTGAGGGCGSCCPGGLRRSLLLHGARSKPYSCPECGKSFGVRKSLIIHHRSHTKERPYECAECEKSFNCHSGLIRHQMTHRGERPYKCSECEKTYSRKEHLQNHQRLHTGERPFQCALCGKSFIRKQNLLKHQRIHTGERPYTCGECGKSFRYKESLKDHLRVHSGGPGPGAPRQLPPPPERD
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Miscellaneous:
MISCELLANEOUS: Present with 2340 molecules/cell in log phase SD medium.
Sequence:
MNSLYELDPKWKKLLKTDNFLGGLTVNEFVQELSKDHRNDVLIDANTKNLPTNEKDQDAIREAIWKQLDPKPYIRTFESTLKELKNLNEETLNKRQYFSEQVATQEVIHSENVIKLSKDLHTTLLTFDKLDDRLTNVTQVVSPLGDKLETAIKKKQNYIQSVELIRRYNDFYSMGKSDIVEQLRLSKNWKLNLKSVKLMKNLLILSSKLETSSIPKTINTKLVIEKYSEMMENELLENFNSAYRENNFTKLNEIAIILNNFNGGVNVIQSFINQHDYFIDTKQIDLENEFENVFIKNVKFKEQLIDFENHSVIIETSMQNLINDVETVIKNESKIVKRVFEEKATHVIQLFIQRVFAQKIEPRFEVLLRNSLSISNLAYVRILHGLFTLFGKFTKSLIDYFQLLEIDDSNQILSTTLEQCFADLFSHYLYDRSKYFGIEKRSLEAILVDMTSKFTVNYDKEINKRVLLDKYKEKLSTNVDAFMHSPRGNTHSRQDSTSRSKLSQFNSFLKTHLDKDHLSLNRTNTLSDSFNNSSSSTQYDVANNSSSLVNSSFTASDIDNSPNSPANYSLNDVDSMLKCVVESTARVMELIPNKAHLYILEILKIMFLGIVDSYMEIALEVAYWKICKVDINKTAGVVNLNFLKFISMSTEILDLLSISIKSIFLPLLNNSPEIKAQIIEMTNSQIQKMEILINIILQETITVISTKFSAILCKQKKKDFVPKSQELLDQDTLPAIEIVNILNLIFEQSSKFLKGKNLQTFLTLIGEELYGLLLSHYSHFQVNSIGGVVVTKDIIGYQTAIEDWGVASLIDKFATLRELANLFTVQPELLESLTKEGHLADIGRDIIQSYISNREDFNHDNFINSVKLNFR
The following text describes a protein:
Function:
Role in flagellar biosynthesis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Sequence:
MISAAYATAIILISFRLFIFFSMVPIFFPKGTPVIGKVSLALIIAYMLVGSIDIRSINTINNSTALIFNIVNEILAGAILGYITNAAFVCARYAGNMMDLQVGFSMMTMFDPSTNSNVTFLERILYWFSTIVFFLIDGHHMLIRALVESFNVIKLGAFFLNQEGIKHVLNVFIQYFYISIKIAVPIVFIILITDLTLGLVARTVPQLNIMILGLPIKILVGLTAFVFALPLFLKVLNSAFGMLPDAIRGFYKTIPVLIIFASEEKTEEATPRKKMDARKKGQVAKSKELALAFTLLACTLVLVALGEYGANELKETMAGFLNNYLNMELNYNNLNSLAILTVLRVGKIVLPVALPIMCFGIAANYLQTGFLFTKEPLKPDFKKLNPINGFKRMFSLRTVMELLKDLTIITVVGIVGYKFLQDNYLKILNLGTLRPWYMITGLLSLAISIFFRITLIMLFIAVADYVYQKYQYNKDLKMTKQEVKEEYKQDEGDPQIKSKIKQKQREMAMQRMMQEVPKATVVVTNPTHIAVALRYEKGDTAPKVVAKGADYVAIKIKDIAKNNEVPVIENKPLARLIYEKVEIDSEVPQDMYEAVAEILAIVYTLKKKK