lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme.
Sequence:
MAQTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALTQRTQQDSTRTVGERLQDTHGWKSELQHEVEALATETNLLLAQKQRLERALDATEVPFSITADNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLQHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDTAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAHRTRYPTILQLAGYQ
The following text describes a protein:
Function:
Catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: Found in 20% of the mRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MADSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ
The following text describes a protein:
Function:
Substrate for type I BMP receptor kinase involved in regulation of some target genes of the BMP signaling pathway. Also regulates the expression of several non-BMP target genes, suggesting a role in other signaling pathways.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus. Note=Detected predominantly in the cytosol. Upon BMP stimulation, a small portion localizes the nucleus.
Domain:
All members of the FAM83 family of proteins share a conserved N-terminal DUF1669 (domain of unknown function 1669) domain of about 300 amino acids. This domain mediates the interaction with casein kinase 1 (CK1) isoforms. Therefore, it has been proposed to rename DUF1669 the polypeptide anchor of CK1 domain.
Sequence:
MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSHSVSLKGIPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEIAKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEEHPSPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDRKDP
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAIVLAIVSLITLYSEPAGDILNGSFVLDGFSKGFKTLLLGASALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFITLFVGLELLSLSSYILVGIRKKSRASNEAAMKYVISGGIGTAITLFGMSYLYGITGSTNIVDMQKVLTGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYEGAATPVTAFLGTISKIAGFLLIIRLFLMIFASVLIQGDMQSLYGHMSIYIAVLASITMIVGNVVALKQYNIKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQNNEENITIFTGLYKRSPFTAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVVSFVYYFRILQQMFFRTGETEERIRLPLNIKVVMSLCAISIVILGIMPMIGYNFFYEYFPLMKDFFFLGNVVQ
The following text describes a protein:
Function:
Important for the epidermal barrier integrity.
Subcellular Localization:
Secreted.
Sequence:
MGSSRAPRMGRVGGHGLMALLMAGFILPGTLAKSIGPFSDPCKDSILLLLLLLSWCFHTTPLGCPLCPITCLETHFFKSLTGKSSKHTSTLGAGISQSVPLPVCRLRQNPISHLRTKVHFSATPPPALI
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MEREFFGLSSKNGAWTTMKDDAVNKSRDQVRSSGMQWSFPNKVSALPQFLSFKTNQEDKPRKTILEPLASSGYMAMSTQYAFDSNQKSFLGLTNRNLSISKHAAGNKQGMTVYPLQCCDAQSEEARIFSVSNQSNQVSPVLQSNLASTGLNMVNSVIKPQPFGSKSSGTPLSILPSIGSIVGSTDLRNNSKSSTMPTQLTIFYAGSVCVYDDISPEKAKAIMLMAGNGYTPTEKMELPTVKLQPAISIPSKDDGFMISQSYPPSTFPTPLPLTSHVNSQPGGGSSSNKEISIIRQVGPSTAPTNHLESPIIGSIGSASKEKAQPVCLPQARKASLARFLEKRKGRMMRTSPYLYMSKKSPECSSSGSDSVSFSLNFSGSCSLPATN
The following text describes a protein:
Function:
May bind to and transport cholesterol and may play a role in ecdysteroid biosynthesis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSNMDPSDVRSTAQLILANARQGNSAYNMQYDMSRAHSINLITEDFLAGYMQDGRMSVVRRFFCLFVTFDLVFVSLLWLICIVINGDNIFTAFHKQIVEYTIYKSLFDVVAVAICRFLVLIFFYAILYINHWSIIALSTSGSCLFLISKVFVFDWLDSKQQVFEVILIITSFILAWGEAWFLDCRVIPQERHAQHYFRTMTSNDRTPMEQPAILIEQERPPQSVTDFYSLMDTARHSDEEDELDDEYTQMGLDCLRKAYEIIESSDWKVEKVNQKGDTIHSTQRDKIGKIYKLTARIKYPAKALMEDLFYRIEDCPKWNPALLESKIVRKINSYTDITYQVSVGGGGGMVKSRDFVNLRSCRLFYNGQICDDDETAQLSSDDGNSSLNRSCEGSVSTISDGDSNTPLLPSSVSSCKATFPTSSKGAAMPFDTLGNSLGAKSLGPIVNFDEEPPPLDQDEFEDAKDKVDGEANNMTKPNVPSVGKTKDRVWVTSAVSVQYAAVPPSPKYTRGQNIVSGFAFREIVGKSDSCIVEWVLCLDLKGYIPRYVLDAALTSSMTDYISNLRKHVNELRQKGRGRAPRTH
The following text describes a protein:
Function:
Catalyzes the ATP-dependent addition of one alpha-linked L-glutamate molecule to coenzyme gamma-F420-2, producing alpha-F420-3, the major form of coenzyme F420 found in M.jannaschii. Thus, caps the gamma-polyglutamate tail of coenzyme F420 with a terminal alpha-linked glutamate. Prefers ATP to other purine nucleotide triphosphates; GTP gives about 25% of the activity observed with ATP. Cannot catalyze the addition of the following amino acids or analogs: D-glutamate, beta-glutamate, L-aspartate, L-glutamine, L-alpha-aminoadipate, or D,L-2-amino-4-phosphono-butyrate.
Sequence:
MVKITILSPEGRSCSVWSLKNEIEKLGAKCDIFLLSSPENLMSHDFKLETDLIHSRCGIGDYFDRLTLYSWQFINALEVEGCRFINPIKTLYLTSDKFKCIKLLAKNKIKTPKTALIRDYEDAVKFIEKYNLRFPVVIKNSFSKCGLKVFMARNYDELKQLTKNAIWEGKLIQEFIDFKENDLYRDMRILVVDGEVVGGYRRVSRDFRTNLYLGNVVEKLNIDEELEELALKCADLSEAVILGVDILPTKDNYYVIELNSSPGTKGFRDIGINADKKIAEALVRYAKS
The following text describes a protein:
Function:
Pseudouridylate synthase that catalyzes pseudouridylation of RNAs, such as tRNAs and mRNAs.
Sequence:
MGKDRGRGRRNNHSGPYNKSNWRGQKKDRPQNNGGGQRNSAPQQKSTLLETQVGITEFTNPEAPGFTGILKSRFSDFHVNEIDSNGKVLELNDLSVPKVAIVAVAENELDNWRKELEAVIGPEVWQDIANLAKAKNDPAIEQKVEIDVTTLDKEQRTQVHQMIKQLYKGKLLSTTIGQQQAKPKVQEEASLENKDAAEGETSTQKDSQVPAEEKKTIKVFKPKPGRGDKRWSFPADYVTFLVHKTNLVTSDVASTLAARLNLRPSQVNYSGIKDKRAKTTQKFSVKRRTPESILVAARSQRNVHIGNFGFESNTLKLGDLQGNRFRIALRHIAKEKREEIEQALQSLKERGFINYYGLQRFGNSASVPTYEVGVALLKHDYKLACELILKPRDSDVEFLRPIREEWWKNRDSAAAAAQIYGEKFIEKKLLDGLARFGESDYSSALRQIPRNMLMLYPHAYQSLIFNRIASRRIKEFGLKLIPGDLVYVEQDQSEASEEQAQQGEALEEQKEEEPNDEPLEVPEGDEAIEEESIFKRKVRPLTAEDIASGKYKLCDVVLPLPGHDITYPSNECGAWYEEMLAEVGLSSDQLKHKEKTYALAGAYRKMIISSSDLKWSFRMYNTPEDTLIASDWELLKNIPVAPEPAEAEANYMALLLEFSLPTAAYATMFLRELLKQDTSSASQTQLEKQAMAKEDNEKKAVGTQEEQMEVVKEVADEDGQETEQAETQGAEEAV
The following text describes a protein:
Function:
Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology. Plays an inhibitory role during neocortex development by regulating mitochondrial morphology, distribution and motility in neocortical neurons.
Subcellular Localization:
Mitochondrion. Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. Mitochondrion inner membrane; Single-pass type IV membrane protein; Cytoplasmic side. Note=Colocalizes with RHOT1, RHOT2, TRAK1 and TRAK2 at the mitochondrion.
Sequence:
MYLRRAVSKTLALPRRAPPGPAPLGKDASLRRMSSRKFPGTSGSNMIYYLVVGVTVSAGGYYTYKALTSKQVRRTEHVAEPKEQTKAELQPLPGEKEEHVAEAEQVCSEPGDTAVTEAESVDAEEVPEAAVVLPEESQASAPSEVPAEAAVVEASLSSSEPELKITEASLVETTESVPESTQEVESAAPDQDDVCNEGADTSQEGADTSQEGADTSQEGADTTKEEADNSKEAEGTTTEDPRSISEESAELEESPPLGSEPPAQPESQEEETQVTEETASPQG
The following text describes a protein:
Function:
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Part of the ciliary targeting complex containing Rab11, ASAP1, RAB3IP and RAB11FIP3 and ARF4 that promotes RAB3IP preciliary vesicle trafficking to mother centriole and ciliogenesis initiation.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Vesicle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein kinase C results in redistribution to the periphery of lamellipodia.
Sequence:
MGLKKMKGLSYDEAFAMANDPLEGFHEVNLASPTSPDLLGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYSSPRRLNCAEISSISFHVTDPAPCSTSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDGSDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVREANIKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLPGGKTPFKKGHTRNKSTSSAMSGSHQDLSVIQPIVKDCKEADLSLYNEFRLWKDEPTMDRTCPFLDKIYQEDIFPCLTFSKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKSCKHRIKLGDSSNYYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL
The following text describes a protein:
Function:
Oxidizes proline to glutamate for use as a carbon and nitrogen source.
Sequence:
MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRDDRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALGLSARVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAETGDLKPIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRCSALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAAGGNAALLAGEE
The following text describes a protein:
Function:
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
Subcellular Localization:
Lysosome.
Sequence:
MDFLNVSSPHTLGVAHLHDLTSQLSPFSRFLFVLQRTAVNASLRLSGLEYQRALRRPEEEATGANLSGLSHPFFLPGQSLVRVGGAVRQHLRIKSGPRRLRAAMRAPGERWRPAGAALWLLLLLLLGATESVRRAQPLRRYTPDWPSLDSRPLPSWFDEAKFGVFIHWGVFSVPAWGSEWFWWNWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQYFVGAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMAMSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLALGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKIMMLGIQGDLKWSTDPDKGLLISLPQLPPSAVPAEFAWTIKLTGVK
The following text describes a protein:
Function:
Has insecticidal activity when consumed by D.melanogaster larvae. Has low chitinase and chitosanase activity.
Subcellular Localization:
Secreted.
Sequence:
SEQQXGRDVGGAL
The following text describes a protein:
Function:
Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle. Lysosome lumen. Membrane; Single-pass type I membrane protein.
Sequence:
MWLPSAMQAVVLKGRVLLLPLLFLLGPQASWGLAIIPPGPELVLNLSSTFVLTCSGPAPVVWERMSQKPPQEMTETQDGTFSSVLTLVNVTGLDTGEYFCGYKRSHGLEASERKRLYIFVPDPSVGFLPVDPEELFIFLTEITETTIPCRVTDPRLVVMLHEKKVDVPLPIAYDPQRGFSGTFEDKTYICKTTIGDREVDSDAYHVYSLQVSSINVSVNAVQTVVRQGENITIMCIVTGNEVVNFEWTYPRMESGRLVEPVTDFLFEMPHIRSILHIPSAELGDSGTYICNVSESVSDHRDEKAINVTVVENGYVRLLGELDPVQFAELHRSRTLQVVFEAYPPPTVMWFKDNRTLGDSSAGEIVLSTRNVSETRYVSELTLVRVKVAEAGYYTMRAFHEDAEAQLSFQLQVNVPVRVLELSESHPANGEQTVRCRGRGMPQPHLTWSTCSDLKRVGRDWKSTWPVLGRCPRELPPTPLGNSSEEESQLETNVTYWAEEQEFEVVSTLRLRHVDQPLSVRCTLHNLLGYDVQEVTVVPHSLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQRCSDKRRPPSAELYSNALPVGLPLPSHVSLPGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYMAPYDNYVPSAPERTCRVTLINESPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFNGLRSPLDSSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQEEPEPEPQPASQVEPEPKWPPDSSCPGPRAEAEDSFL
The following text describes a protein:
Function:
Serine-type protease active in vitro against the LHCII N-terminal. Cleaves its substrate on the carboxy-side of Glu residues.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MSALSILHRACLRLALLPLPLAPLRAPLRSSSLPRPLRLPRRTAMSSAASRMSHIAAAAASGESNQPAAASGLGQEDDDLSLGYRLPPKEIQDIVDAPPLPVLSFSPSKDKILFLKRRALPPLSDLAKPEEKLAGVRIDGHSNTRSRMSSYTGIGIHKLMDDGTLGPEKVVHGYPEGAKINFVTWSHDGRNLSFSVRVEEEDNKISKLRVWIADVESGEARPLFKSPDIYLNAIFDSFVWVDNSTLLVCTIPVSRGALPQKPSVPSGPKIQSNETKNVVQVRTFQDLLKDEYDADLFDYYATSQLMLVSLDGTVKPMGPPAVYTSIDPSPDDKYLMLSSIHRPYSYIVPCGRFPKRVELWTADGKFIRELCDLPLAEDIPIATSSVRKGKRSIYWRPDKPSTLYWVETQDGGDAKVEVSPRDIVYMENAEPINGEQPEILHKLDLRYGGISWCDESLALVYESWYKTRKTRTWVVAPDKKDVSPCILFDRSSEDVYSDPGSPMLRRTAMGTYVIAKVNKQDESTYLLLNGMGATPEGNVPFLDLFDINTGSKERIWESDKEKYFETVVALMSDKIDGDLPLDQLKILTSKESKTENTQYYLQIWPEKKQVQITNFPHPYPQLASLYKEMIRYQRKDGVQLTAKLYLPPGYDQSKDGPLPCLVWSYPGEFKSKDAAGQVRGSPNEFSGIGATSPLLWLARGFAILSGPTIPIVGEGDVEANDSYVEQLVTSAEAAVEEVVRRGVVHPDKIAVGGHSYGAFMTANLLAHAPHLFCCGIARSGAYNRTLTPFGFQNEDRTLWEATNTYVEMSPFMSANKIKRPILLIHGEQDNNSGTLTMQSDRFFNALKGHGVQSRLVILPFESHGYSARESIMHVLWESDRWLQKYCVNGTSKADSETAADGESKTLAASGGGAAPEGLSSDGFSSIPRSLL
The following text describes a protein:
Function:
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
Sequence:
MSTLTDTIQIENVVASTDLSQELALEQLATDLPGAEYNPGDFPGVIYRLDDPKSATLIFDSGKAVCTGAQSVDDVHDAISIVVEDLRDLGIDIPPSPPVHVQNIVCSGSLDQDLNLNAIAIGLGLEDVEYEPEQFPGLVYRLNDPDVVVLLFGSGKLVITGGSNPDDAHHALEIIHERLTDLGLLE
The following text describes a protein:
Function:
Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex.
Sequence:
MADFLKGLPVYNESNFSRFHADSVCKASNRRPSVYLPTREYPSDQIIVTEKTNILLRYLHQQWDKKNAAKKRDQDQLEIGETSAPPRKIARTDSQEMNEDT
The following text describes a protein:
Function:
May function in the process of apoptosis.
Sequence:
MAEEELEALRRQRLAELQAKHGDPGDAAQQEAKHREAEMRNSILAQVLDQSARARLSNLALVKPEKTKAVENYLIQMARYGQLSEKVSLDSLEELYCYLLYQNMASEGQLHLHWITEFLLTLRRNCWRE
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MSKIAGKRLVYFPNITFTLCRGLNLQPKFAVFRVPLHVNKFDVRDYLQHVYNLKVVSVKSRIYQGKLFRNQLGQVKRPQSEKRVIVEMEEPFVYPNAPNDLKDWQEGELLPDGSNVKTLSRYPKVLEQVDMKRVNEELSKLQDKQILESQQKIARLLKKKY
The following text describes a protein:
Function:
Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP).
Sequence:
MVRIACVGITVMDRIYYVEGLPTEGGKYVAKRYTEVGGGPAATAAVAAAKLGAQVDFIGRVGDDDTGNSLLAELESLGVNTRYTRRYTQAMSSQSAIMVDAKGERIIVNYPSPDLLPDADWLNDIDFSQWDVVLADVRWHDGAKQAFTLARQAGVMTVLDGDITPQDISELVALSDHAAFSEPGLARLTGMSEAIDALKKAQMLTNGHVYVTRGSEGCNWLEKAAVRHQPGFTVEVVDTTGAGDVFHGALAFGLASGYAIEEAVRFASGVAALKCTRPGGRAGIPDCEQTRSFLSLFV
The following text describes a protein:
Function:
Probably in association with the cell surface receptor unc-40, positively modulates the BMP-like Sma/Mab signaling pathway through interaction with both the ligand dbl-1 and its type I receptor sma-6. Regulates body size and this may be through modulation of the Sma/Mab signaling pathway.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MSIVYLVSITFIFSVFKPITSCRVEECAAWFQKTKDYENLVPKATERYCQVLQTYLKCMNDTQRYCHGNLRFHSSELIMRRHWKEFECEKWESCNDNSHVKRKHVNTCYFNPPPSNRKLKYCSLFGDPHLIMFNGSVQTCSEEGARPLVDNRYFLVQVTNRNVRGEALTTTVTKVTVLVRKHNCTASLRYEASSDEEGLPRGFVDGTTFQMTSKHSVEVLWQDDNYVEIALHFIHSSIHIRRQGPYLSVSVRAPTIVLETGGDVARELCWSGCRKSSRIPAELAVEMTKKFAECYRRRVHVPKKVAEDRCKDIGNIGVFFDACVFDLMFTGDDYLVHLSRAAESDFRRLAPHHFQSHVTQQHARFQKENQHKNHINQSEIFKKCIPSKSIRFYPFLAIFFFALLSLLC
The following text describes a protein:
Function:
Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
Subcellular Localization:
Cytoplasm.
Sequence:
MSDQLILVLNCGSSSLKGAVIDRKSGSVVLSCLGERLTTPEAVITFNKDGNKRQVPLSGRNCHAGAVGMLLNELEKHGLHDRIKAIGHRIAHGGEKYSESVLIDQAVMDELNACIPLAPLHNPANISGILAAQEHFPGLPNVGVMDTSFHQTMPERAYTYAVPRELRKKYAFRRYGFHGTSMRYVAPEAARILGKPLEDIRMIIAHLGNGASITAIKNGKSVDTSMGFTPIEGLVMGTRCGDIDPGVYSYLTSHAGMDVAQVDEMLNKKSGLLGISELSNDCRTLEIAADEGHEGARLALEVMTYRLAKYIASMAVGCGGVDALVFTGGIGENSRNIRAKTVSYLDFLGLHIDTKANMEKRYGNSGIISPTDSSPAVLVVPTNEELMIACDTAELAGIL
The following text describes a protein:
Function:
RNA-binding protein involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MASPERYQERESLKKDISQDDGGKKAAPISFGFSKTLIKVKSGKAEERDYLVEVEGKELKGTKPVEKPKELIIPLIHKNRWYRQDAERADKTSEEKTEEPSQVKQDTVESQAVKELIEESQKYQDRWKNGPQSDPNFAIPLLMQNQVPDGFEDGDKVNVDLRPESSTEADYERVPVEAYGLAMLKGMGWKQEEGIGRTFKQDVKPIEHQLRPKGLGLGADRSAIKDLEPGVPKRPPKPGDEKGKEEEALVLGPGGCVQVLAGAHKDLYGKIEGVDPDNGRVVVKLAIGGKTVTIIQHSIKLVTRKEYDKYSKDLSRLSKAHKDKEREKEREQKREQEQRLNGKDERGKTDRSREKDRDQKKRKHRESSTDREKPPPAKESRSSPPAPSWLQRDLRVRFIDKAFKGGKYYNSKMRVEDVLTPHTCVCRTEEGRMLDDIRQKMLETIVPKNDSDYIMVVLGEHRGQVGRILKRDREKCRAMVQLDRYEERVFTLDYDTICHYVGGTDH
The following text describes a protein:
Function:
Catalyzes the hydrolysis of epoxide-containing fatty acids. Active in vitro against epoxyeicosatrienoic acids (EETs) including 8,9-EET, 9,10-EET, 11,12-EET and 14,15-EET and leukotoxin.
Sequence:
MPELVVTALLAPSRLSLKLLRAFMWSLVFSVALVAAAVYGCIAFTHVLCRPRRGCCGRRRSACPACLSDPSLGEHGFLNLQSSGLRLHYVSAGQGKGPLMLFLHGFPENWFSWRYQLREFQSRFHVVAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCVLVAHDWGALLAWHFSIYYPSLVERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQILKTALTHHKTGIPRLTPNELEAFLYNFSQPGGLTGPLNYYRNLFRNFPLEPQELATPTLLLWGEKDTYLEQGLVEAISSRFVPGRLEAHILPGMGHWIPQSNPQEMHQYMWAFLQDLLD
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MEWNGNTRSFVPQPESSLSFLYNYNQCSYQGMMEVKHQDWTDTMFPEMEKMMKYGNQEKKKRLTSEQMESLESSFQEEIKLDPQRKMKLSKELGLQPRQIAIWFQNRRARWKTKQLEHLYDSLRHQFEVVSKEKQQLQDEVMKLKAMLKEQGNSCGRMQGYYTEMSVEETETVESTSEAALRCSNREVKGKIHQQLNIDEGNCSFNLEDYNINNNVPLLPYWPAAVPYNYHP
The following text describes a protein:
Function:
Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. May act by recruiting heterochromatin proteins such as CBX5 (HP1 alpha), HDAC5 and MBD1. Represses IGF2 expression by binding to its CpG-rich P3 promoter and recruiting heterochromatin proteins (By similarity).
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to heterochromatin and inactive X chromosome. Colocalizes with histone H3 trimethylated at 'Lys-27' (H3K27me3) (By similarity).
Domain:
The BAH domain is required for localization at H3K27me3.
Sequence:
MTHTRRKSLPMLSSGPTGRGEPLQMEDSNMEQGTEDVEPGMPESPGHLTGRRKNYPLRKRSLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPTSSSEDAGLVQPRKRRLASLNAEALNNLLLEREETSSLAGARRSRGGDPHRSRDRATGSWSFSKKRPRLGDLGEGSRDLSPELAPDEGARRDGDPAPKRLASLNAAAFLKLSQERELPLRPSRAQAEADGRSTEPLAPRILRPKVNGKNCPKARQGAGSGEATGPPNWQEQPDERWPSAPPHGPPTQPSHQAPGKALENPLRPNLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPAPQLSPLPMPGNPADYSGPCGGPELTALGSFYLYCGQDGLQCGAYSPCPMLPEGKLSPVAAPNEGLLMAPSSVPSGVPFQHPPWSAPRYCSSEDTGANGYSICGVLPLSLTHIGTTCGGCPYKMPFTAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPIPHLQTPISEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTVRSKAARRPSHPKQPRAQRPRPRRRRRRRTNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVERHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPPHRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ
The following text describes a protein:
Function:
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MGSAVGFALRKLFVYISAVLMVCAAILRMSMLKLLSFISPGRMRKIHMKMGERTTMTQNPKFRYEDWGPAFFSLAFIKTLFFVNWCSLGLEAFEGHSAPDSALITLDRQKTSVHRFLKGNRPLVLSFGSCTUPPFLYKLDEFKQLVKDFSNVADFLIVYLAEAHATDAWAFKNNVDISVHKNLEERLAAARTLLKEDPPCPVVVDEMNNITASKYGALPERLYVIQSGKVIYQGGIGPWGYKPEEVRKVLEKSK
The following text describes a protein:
Function:
Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway; the 2 periplasmic Cys residues of MgrB are required for its action on PhoQ, and thus PhoP.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW