lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.
Subcellular Localization:
Mitochondrion.
Sequence:
MFRIISKATLFQDSQRFHTSILSPRCAFHNGGILHKKAKDKDVKHDHDPEFANSFNKMLKSFEAKMQLVHEKLAKRFQEAVVLPSQGNFTQLEALFIPSKSIKAPTPSRLLREIAAVSQKGSQQIIIRPFEDVDIKNILKAIEDSRYPFVANKLNASTIEVKPQRTTLESRQQLAKVLEGYAKDSREQLSAMRTELKKEIAKNKKSKAWTSDDCYKAEAEMQTAFKNAINLLDSGLKSALKKVI
The following text describes a protein:
Function:
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MPTLELLRRKIETASDLQSVVTTMKTLAAVRIHQYQRAADALMDYNRTIELGLQVILREQRLQPLQTSEWGGQNRPSSGHENGSHHGVIVFGSDQGMCGQFNEQIATHALEHHAKHCRRPPEALWIVGARVAFLSTDSGWLIDEAFRIPTTVPEIADCVSDLLTAVEAVREQRNLTKLRIYSNKRSSAGSYQPNTTQLLPIDFAWLKQLSVKQWESPCLPTFGGEREELFSRLVRESLYVSLYQACAESLASENASRIAAMQAAEKNIEETLDELNTAFKTQRQTAITEELLDVVVGFEALTQSER
The following text describes a protein:
Function:
Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.
Subcellular Localization:
Mitochondrion.
Sequence:
MLRSCGRAGKPLRRLAAVQTRGYRDPYHVSWHFNFKPEAVEPPTGHRLTDNLSIALNKRNKKENGTGALKLALEICETSGPEAITPILYGQLLENVYEEVRGIPISKLRTYNTARLQVLESLSHFVPGLNARHYTYLIKLAHLTRRPKQVQDAWEQAMLNECDKTSALYNAYLKARTDASPRLRGNSDMPDLAGAKFWATNKDVSDSRAHALDPIEFMNEMRDRGIEPTRITYAIALNHYGQQNNLPMAVSICENLWGVGFNSGKLEGPRVPHTSIMHPTPFTLISIIDAFGLNDRLVEGKAYCETIADIYGIRLDSQLAQGYWTHLMRHALYTGIPHGQSSKEMCNSVWSNIVEFDYPPSPAQYSLRIRDLLARDRLEDLQTLMHYALSVDKVGEMAAVVSTYIGLLLRRYTTTGNFPKAIEVARTFQEHTQMQEFISTKIHELEQQYKMAGNVPVGGEEGNELDILDSALVQELKYIPEDEEDEENFLQL
The following text describes a protein:
Function:
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
Sequence:
MKSDKPFLERYFYDPTLLQKGLIFALYPFSLIYQGIATLKRKTAKKHDFKIPIISIGNLIAGGSGKTPFILEIAPRYQEVAVVSRGYQRDSKGLVVVSVKGNILVSQKTAGDEAYLLALNLKQASVIVSEKRELGVLKALELGAKIVFLDDGFRFNFNQFNLLLKPKVPPYYPFCLPSGLYRESIKSYEEAHLVVTEDKDYQRITSISRPTKRMLLVTAIANPSRLDAFLPKEVVKKLYFKDHAPFNLELLEKEFYQNNATSLLVTSKDLVKLQDCNLPLSVLNLKLEICPKVLEEIDHYILSYPYNTKERL
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.
Subcellular Localization:
Nucleus.
Sequence:
MNISNPVSAEVRSVHFSFYSPQDLRKLSVKQITNPIIFDNLDHPTPQGLYDSALGPSGIDSTCSTCSLGFSNCPGHFGHIELSVPVYNSVNFKLLYKLLQSTCYYCHHLRTSRSVIHSFVAKLKLIHAGLIVEAAELDSAFPKNSSSTNKSSTFINDEAEEDHEDMISKSFMNVDTEDSEPQDSAGSVNFEKRTSAQIIAAIDRFVDQAFAKNPYTRPSKVTLLTANIRRLERQFFSAIPAQTCQNCRGQSPKFRKDGESKIFEQPLNNKQKMSMNTQNLTPENLFGPKMHAVDDDNEKTAQQGDAVSQAIDSQREIFLTPLQVKAHIELLWKRETVVLDLLFGNSSSKKSPRVSSPLMFFLDVVSVTPNRFRPISKMGDSQYENPQNIFLTAILKANVSIQELQRQEEAALKVIADDPKLYQLQKAEFLRRIIDAWMILQNSVNYLLDSSKCPLSVSGKIAPPGIRQLLEKKEGLFRKHMMGKRVNHAARSVISPDPYIETNEIGIPPVFASKLTYPEPVTHHNIKEMRRCVVNGPLKWPGATHVENEDGTLISLSSFDDAGRTAIANQLLTPSMHHGETNHSYNFDHVNKKVYRHIRNGDFLLLNRQPTLHKPSIMAHTARVLPGEKTIRMHYANCNTYNADFDGDEMNIHFPQNEIARAEAMLIARNDQQYLVPTDGGVLRGLIQDHVDAGVDMCSRDTFFNRETYMQLVYIGLCPEGIIGRNGRVVTLPPAIIKPVAKWTGKQIISTILVNLIPEDRNLLNLVSKSRIPAKQWGPSAPEEQTVIFMDGDLLTGILDKSQFGASANGLVHAVYEVYGASYAGKLLSILGRLFTSYLQFAGFTCRMDDLRLTPEGDAVRCELIESASSIGLDAISEITGGDKTALAKNIELNVALEQVLRNSEKMAALDSAMKSRTNKVTSKIISSCVPDRLLKPFPHNNMQVMTVSGAKGSGVNVSQISCLLGQQELEGKRVPTMISGKTLPSFLAYDTSARAGGYITGRFLTGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLIKHLEGLSVHYDHTVRDMDGSLLQFQYGEDALDVVKQTTLQKFDFCALNYRALLKRYDPSALAGKVDDESLERYLKKQRKQDRESIRESGGSFKPNHDPILSIFSPSRHIGSVSDGFADALSAYIEKNTSQLLYTSSSKKTHKNRTDENGEARPVKDTWSVPKISARKFKVLMELRYMHSLVEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGFGAKNVTLGIPRLREIIMTASQSIQTPLMRLPLKQEATVDQAHQIADQISRVVLSQIMHGVTVSETLVPKTPERQKRVKQFCVRLELWPQEACQRQYGITDEDIGNIIEKKFVPILDRTIMRMLKVKFTGDNASTEADEGQTLAKGDDSEVSDDDGDNDATAVRQNTKRQQQATYDGPDEDDEQVIEHLADIEMANDDDKVSVNTDPDSVNDADDGLDLDGFETEKHTNGINRSVRIQRASRFVSGYKFHKGSLRYCELTYELSTDTKKILMLPLVEEVCSNLIVRQVPGVSRCYYLPNESENDKSVNVGTDGVNLKGIWEYDNVIDVNKIGTNDIAAILHTYGVEAARAAIMQEIAGVFGVYGIQVDSRHLSIIADYMTFEGGYKAFNRTCMGSNPSPFLQMSFETTTSFLTTATLTGDSDPLDSPSARIVMGQAVKTGTGSFSVLQPLVRSARG
The following text describes a protein:
Function:
3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. Essential for early development, possibly by participating in silencing certain maternal mRNAs translationally. May have a pivotal role in stress response.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice site; MISCELLANEOUS: [Isoform 3]: May be due to intron retention.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Only cytoplasmic.
Sequence:
MRRHKRWPLRSLVCSFSSSAAETVTTSTAASATAAFPLKHVTRSNFETTLNDLRSLVKAADFVAIDLEMTGVTSAPWRDSLEFDRYDVRYLKVKDSAEKFAVVQFGVCPFRWDSRTQSFVSYPHNFFVFPRQELTFDPPAHEFLCQTTSMDFLAKYQFDFNTCIHEGISYLSRREEEEASKRLKMLHGEDGIDSSGETEELKLVRLADVLFAARMEKLLNEWRSGLLHGGNASSEFPRISNGSNQSMETVFHHMRPALSLKGFTSHQLRVLNSVLRKHFGDLVYIHSNDKSSSSRDIVVYTDSDSDKENLMKEAKDERKRLAERKIQSAIGFRQVIDLLASEKKLIVGHNCFLDIAHVYSKFVGPLPSTAEKFVASINSHFPYIVDTKILLNVNPMLHQRMKKSSTSLSSAFSSLCPQIEFSSRSSDSFLQQRVNIDVEIDNVRCSNWNAGGKHEAGYDAFMTGCIFAQACNHLGFDFKQHSQLDDFAQNEKLEKYINRLYLSWTRGDIIDLRTGHSNADNWRVSKFKYENIVLIWNFPRKLKARGIKECICKAFGSASVTSVYHVDDSAVFVLFKNSELVWDFLALKRQLESSDGPVSVLHPLSKILEGGNTGAADYEAYKEICSSHVSEVMFSDQAETVGVKSRTRPNAQCETETREENTVTVTHKASDLIDAFLANRVEVETATSN
The following text describes a protein:
Function:
Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MSILYQLFVWLCLVYSPGLCSHRGKRAITSFRVTLPGSGQAVNEVNAGVEVHITCDVTGDPSPDVDIYKYSEAGQNLGSLSAVSDGNNYQALPNSDVTQLGIKTYRFTPVMNGTFRCENHGDEMTLQLIVKHPPVPLDPPTTAQEEQGDVIVYRSTAYRGDGPVVAMAVQYRPFGGDVDVWNTTAEVTEDSYVISGLPVGNRYKVRLVLVRPGEGGRGAPGPDVTVRIQFIEGDTFSGSVIVGSLLGIIILAVLTVAILHTVYKARKEENMFALATFQLERGELTSIPKEMTGKRLAYLRLHTGEWKKTGTYRVEAEELDKYMETTGFDGLIWQFEALPDELIYKCKVARRPENTPKNRYTNSIPYDYSRVELQPLPGKPTTNSDYINASWVNGYSKSKAFIATQGPSAETVDDFWRMIWDYGPKYIVMLSDLIDKSKVPCAQYWPDKEASLRSGDLLVTLKKKDVMADYIFRTFTLQKAGDDASQYEITHIQYTGWPQHRAGTPPYSTSLLNIIRTIKLTDPEEMETPIVVHCGSGVDQTGVFIALYAMTDMLEEEAAVNIREFVVQMREYRCLMVSCVDHYLYIYGSVLEAERCGKTVTRTDQFLTYAESKLGLTGSKRGALYCQEFAKLQTLCPNPSAERTATGALPVNEGKNRFSNLLPDDKRRVTLSTPLSDTDSNDYINAVYLDSYKSQKGYIVTQAPLPNTVTDFWCMISDTGSNIIVMLNSISESCPRYWPAHASATYGPFNVEVTNTQIAPHVTEREFQLTNTFNHKKTTVRQFQLTNYTDDGDSAPLTAPEYLHQLWAEVHKWFKQSNMDGPITVHCESGAGLSGVFCTVDMTLDRSEVERAVDVFQAVRMLRHHRPEMVCTEDQYKLCYQVVQKHLQTTITTTD
The following text describes a protein:
Function:
Involved in the biosynthesis of the indolocarbazole antitumor agent rebeccamycin. It generates the imine form of 7-chloroindole 3-pyruvate (7Cl-IPA) from 7-chloro-L-tryptophan (7Cl-Trp), with concomitant two-electron reduction of O(2) to H(2)O(2). The enzyme is also active with L-tryptophan as substrate.
Sequence:
MSRGHKKITVLGAGVAGLVAAHELEELGHEVEVLEGSDRLGGRVHTHRFGEGGSVPFVELGAMRIPTKHRHTIDYIGKLGLTPKLKEFKTLFSDDGAYHTTSAGFVRVRDAAKVLVDEFRLLMSGRDLREETILFGAWLTAVGDAIAPADFRAALRTDFTADLLEVVDRIDLDPFLVGAARDQFDLHAFFAAHPEVRTSCTGKLNRFVDDILDETSPRLLRLEGGMDQLVDALVERIRGDIRTGHEVSAIDVREDHVAVTVHNGHGVNTLRSDHVLCTIPFSVLRNLRLTGLSTDKLEIIHDVKYWSATKVAFRCREPFWERDGINGGASFGGGRIRQTYYPPVEGDPTRGAVLLASYTMGDDADVLGGMPEAQRHEVVLDEVGRMHPELHEPGMVVEAVSRAWGEDRWSNGAGVTRWGKDVAACEEERDRAARPEGRLYFAGEHCSSTTAWIDGAVESALAAVRAIEAGDGR
The following text describes a protein:
Function:
Transfers N-acetylgalactosamine onto carbohydrate substrates. Involved in susceptibility to pore-forming crystal toxins in conjunction with bre-1, bre-3, bre-4, and bre-5. Involved in resistance to the nematotoxic C.cinerea galectin Cgl2.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MPRFNRLSVLLPILIFTFWFLCLKSSEKVEEPSLLADEAPKQNCTKNGWLGGSTAPETQDFGSEFMISFANIQKNYTWLYLPTIEETSKETDILMIVASRTDSYARRNIMRQTWMNKSNSEIVANGRMKSLFLVGLAPADYKVKKMVMQEAKLYGDIIIVDMDDTYEELIYKSLMIFLFGVSKAPQYKIIGKIDEDIMFFPDKLMALYEQGIIDSTPVSLYGLVIPAGRDIFRDKTNRWYVPESAYSCSQYPAYLSGMYYMATREAAQMLLKSTKHRDFIQVEDVLLTGILAEDLGIPIRDMPKLYKFPHDIKKNDNKDIIAWHNYKNNIPYLNFFMKGLARYRSEKGLTRTSTTSG
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MPVAKNCYCGTCKEKSSFTMTYNRLSSLLKEKASLRDIRINTTSPVTERNKTTVDLLSKIESPVQMSEKTEKSINHLPQYVTVDSFCKPDDSSNRVVSGEVVEPKTAQMTIIYRGQVLVFDSISADKARDIMLAAAASSSSFDNQIMNRIPLASTSNSASEGFGSRYRMLPGLQINGSDLPIARRSSLHKFLSKRRDRANERAPYRLPNRLMAAPSSNHKFDLNL
The following text describes a protein:
Function:
Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein.
Sequence:
MGTRPPKALLLLLLLRLLPPRGASAGSLQSPGLSECFQVNGADYRGHQNRTGPRGAGRPCLYWDQTQQHSYSSASDPQGRWGLGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPTCHMPGYLGCFVDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRPAPATDCDQICFGHPGQLCGGDGRLGIYEVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSWVLAPPGAALELAFRLFELADSHDRLELRDATSGSLLRAFDGARPPPPGPLRLRAAVLRLIFRSDARGHAQGFALTFQGLQDADADPAPLEGSTQTPAVPLDGANVSCSPGPGGPEASMGAQVFSTVTAVSVLLLLVLSLLRLLRGRGCLLAPGKGSPTLGPSRDPTRSWAVWYRRPRGVALPCPPGDPQVEGLTASYRPLSASSQSSLRSLISAL
The following text describes a protein:
Function:
Involved in resistance to streptothricin, a broad-spectrum antibiotic produced by streptomycetes. Detoxifies streptothricin via acetylation of the beta amino group of the first beta-lysyl moiety of streptothricin.
Sequence:
MIMKMTHLNMKDFNKPNEPFVVFGRMIPAFENGVWTYTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFPTANEIAIFWYYKF
The following text describes a protein:
Function:
Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles. However, it probably also participates in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering.
Miscellaneous:
MISCELLANEOUS: [Isoform 3]: Incomplete sequence.
Subcellular Localization:
Cytoplasmic vesicle membrane. Synapse. Note=Membrane-associated to vesicles. Restricted to all classes of presynaptic termini independent of the ratio of vesicular content (dense core vesicles versus synaptic vesicles). Found in all identified classes of peripheral and central synapses. In the CNS, it is highly enriched in the synapse-dense neuropil, which lacks cell bodies. Present in all synapses in the neuropil where it precisely colocalizes with other pansynaptic markers. Similarly abundant in all classes of neuromuscular junction (NMJ) termini, including type I, II, and III NMJs, where it localizes to all 3 bouton types. Expressed at similar levels in boutons which contain primarily small clear glutamatergic vesicles, as well as boutons very highly enriched in large DCVs. It appears that neither bouton class contains a pure population of either SVs or DCVs, but only differs dramatically in the relative abundance of the vesicular classes. Thus, the level of expression does not correlate with the abundance of DCVs. Clearly present presynaptically and colocalizes exclusively with presynaptic markers.
Domain:
The PH domain is essential for regulated exocytosis and binds phospholipids.
Sequence:
MIDPSSSEEEGEDDAVPNVSSKGRLTNTTKGTSAVSIIGGSAGSVVGSNIPVSGSNTDLIGNQRQSNISSICNRNDVGNISVAALGSTSNKIEQICGNRADTGNLEVPSNGIPSGISQETLNQSVGSSRANSLPRPLSPSPSLTSEKHETAEPHGKHEREEEERKRRIQLYVFISRCISYPFNAKQPTDMTKRQTKISKQQLEIITQRFQAFLKGETQIMADEAFQNAVQSYHDVFLKSERVLKMVQSGASSQHDFREVFRNNIEKRVRSLPEIDGLSKETVLTSWMAKFDIILKGTGEEDSKRPSRMQQSLNSELILSKEQLYDMFQQILLVKKFEHQILFNALMLDSADEQAAAIRRELDGRMQRVGEMEKNRKLMPKFVLKEMESLYVEELKSSINLLMANLESLPVSKGNMDSKYGLQKLKRYNHSTPSFLKLILRSHGSLSKLEGDSEDGSTQLTKLDVVLTFQLEVIVMEVENGEKLQTDQAEASKPMWDTQGDFTTTHPLPVVKVKLYTENPGMLALEDKELGKVTLKPTPLSSKSPEWHRMIVPKNLPDQDIRIKIACRLDKPLNMKHCGYLYAIGKSVWKKWKRRYFVLVQVSQYTFAMCSYKEKKSEPSEMMQLDGYTVDYIEAASANLMFGIDLNGGRYFFNAVREGDSISFACDDENECSLWVMAMYRATGQSHKPTPPITQDKNSAMSKIQGDADKARKHGMEDFISTDPCTFDHATLFKTLQNLTLEYRLNDPYASLGWFSPGQVFVLDEYCARYGVRGCYRHLCYLSDLLDRAEKQHMIDPTLIHYSFAFCASHVHGNRPDGVGSITHEEKEKFSEIKERLRQLLEFQITNFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPPEEVRQMIKKSLETAALVNYTRLSNKAKIDEDLRGDVIVPAPKKLEDLIHLAELCVDLLQQNEEHYGEAFAWFSDLLVEHAEIFWSLFAVDMDRVLSEQAPDTWDSFPLFQILNDYLRTDDNLRNGRFHQHLRDTFAPLVVRYVDLMESSIAQSIHKGFEKERWESKGINAALNPAALNNAAQALNTAALNPSMILCGKKDQVNFYVPKLPKQSNSTAANDEMRNGCATSEDLFWKLDALQSFIRDLHWPDAEFRQHLEQRLKMMAVDMIEQCIQRTDSSFQSWLKKNIAFISTDYILPSEMCAMVNVILDAKNQSFKLTTIDGIDLYKFHAKIDDQIDKANVAMTQGLSGKLMSVLESTLSKLARYDEGSLIGSILSFTNVSSSGKDLGQGYVNFFRNNMDQVRGKIADDLWTLHFFEQWYSQQINMLCNWLSERVDHALHYAQVASISHIIKKIYSDFELQGVLEDKLNSKAYQAVAQRMATEEATCALTMPDACEDEPCDEIREGEEEDNGDESTSNIPRGLPKPKVAAAQAAAVTNVVAGRVGNLLGKGIGGLSSKLGSGSWF
The following text describes a protein:
Function:
HflC and HflK could regulate a protease.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MGRLSIVLIAVILGIGLSSVMVVNEGERAIVARFGEIVKDNVDGKQVTRVFSPGLHFKVPVIDKVKLLDARIQTLDGAADRFVTSEKKDLMVDSYVKWRIFDFEKYYLSTNGGIKSNAETLLQRKINNDLRTEFGRRTIKEIVSGQRDELQNNALANAAESAKDLGIEVVDVRVKQINLPANVSNSIYQRMRAERQAVAKEHRAQGKEQSEIIRATIDANVTVKIAEAERKALTIRGEGDALAAKIYSDAYNKDPEFFSFMRSLDAYRASFSGNSDIMVLEPDSEFFKYMKSSAAKK
The following text describes a protein:
Function:
Transcriptional regulator.
Subcellular Localization:
Nucleus.
Sequence:
MSQEYPERPQESAEAPLERIVSFSKLNAQAPEFVPRAQAQAHVSAYMYPSFQVSGTGWIYGGESGQLQMVSTSSSKEILTDELKQKIIKQVEYHLSDSSLATNDYLMKQMNKDPEGYVSISLIASFKKIKALVNNNHMLATALRSSSKLVVSEDGKKVRRQQRLTDTDIEEFQSRAVVVENLPSDHSHQNLEKIFGVVGSVKTVRVCNPPASSTSGSLSSKSPKTDMLVSNKLHALVEFETVEQAEKAVAELNNEKNWRSGLRVRHLLRRSPKSVRCRKLDCDNTDVNCEDDAALPSNESVEDGSQSSKQPAEQNGDDDVEEREGGSRRGRGRGRGRSRGAGQGRPPSQLGNVGSTQSESTNKQTPHSPRMPDGTRGFTMGRGKSVISSLSALD
The following text describes a protein:
Function:
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Sequence:
MKLSEIAHFFNAKIEGDSEIEISGIKGFEDAQEGDITYIASSKYAELAKNSKASAFIVKEKIPNLNKPQLITENPQFVFAKLLEMFYVKPQPCKGISEKSIVASTAQIGKNVTVYPFVYIDENVTIGDNTIIYPFTFIGKETLIGSDCVIYPNVTVRERVKIGNRVIIHAGTQIGSDGFGYIFHEGKHHKIPQVGGVIIEDDVEIGACVTIDRATTGNTFIGKGTKIDNLVQIAHNVKIGQNVIIVAQVGIAGSSQVGDGCILAGQVGISDHVEIEAGTIITAQSGVMPGKVQKGVFSGSPIMPHREWLRTNAIFQKLPELYKKIRELEERIKQLEKQKTIE
The following text describes a protein:
Function:
Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins; Probable hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
Sequence:
MAKLKIVGGRPITMDEAIELRQTVFGSAASPPRGEWTRTGFTFGPANQEYPYGLRTPRNATRGMQSVIQAHIIKQFIFDNKPRDKSVPLEELLKPNEAEQALSLYTAMSDILWNIGEKAKAIVALPGEASHIPHSHVYFQDNVTEKLYFFEFTKLDDLQIFMKRYLPYFTENPGPGTLLYLYSAVLTRGMENMRNDLDAPKGAHLMGPHEEGSLNVITLLLTGRATPYLHNGVVYVGDEDHYAVPQFGILSRGAIGLLVWEGENEAMRSASRMPGSRLKTPATPVWVSCCCGHYGVLFNSNRELLRNYHAEKRFELHYYTCAGCYLSMTVDNRGQDEGGGDNGDQDGDRKRDDMVSTPLERLIHTKWMDAKITYHGALPASLNF
The following text describes a protein:
Function:
[[Thr6]-bradykinin]: Induces relaxation of rat smooth muscle from tail artery (EC(50)=16.8 nM) and contraction of that from ileum (EC(50)=205 nM), urinary bladder (EC(50)=895 nM) and uterus (EC(50)=60.3 nM). Binds to both bradykinin receptor B1 (BDKRB1) and B2 (BDKRB2); [Hyp3,Thr6]-bradykinin: Induces relaxation of rat smooth muscle from tail artery (EC(50)=56.7 nM) and contraction of that from ileum (EC(50)=588 nM), urinary bladder (EC(50)=4.6 uM) and uterus (EC(50)=3.9 nM). Binds to both bradykinin receptor B1 (BDKRB1) and B2 (BDKRB2). In arterial smooth muscle, the effect via BDKRB1 is stronger, in uterus, ileum and urinary bladder the effect via BDKRB2; [[Thr6]-bradykinyl-Val,Asp]: Induces relaxation of rat smooth muscle from tail artery (EC(50)=10.8 nM) and contraction of that from ileum (EC(50)=645 nM), urinary bladder (EC(50)=1.1 uM) and uterus (EC(50)=1.2 uM). Binds to both bradykinin receptor B1 (BDKRB1) and B2 (BDKRB2). Apart from uterus smooth muscle, the effect via BDKRB2 is stronger; [Hyp3,Thr6]-bradykinyl-Val,Asp: Induces relaxation of rat smooth muscle from tail artery (EC(50)=3.5 nM) and contraction of that from ileum (EC(50)=223 nM), urinary bladder (EC(50)=1.5 uM) and uterus (EC(50)=356 nM). Binds to both bradykinin receptor B1 (BDKRB1) and B2 (BDKRB2); the effects via BDKRB2 are stronger.
Subcellular Localization:
Secreted.
Sequence:
MSFLKKSLFLVLFLGFVSFSICEEEKREDEEEENEREENKESEEKRNQEERPPGFTPFRVD
The following text describes a protein:
Function:
Activates expression of the rhaBAD and rhaT operons.
Subcellular Localization:
Cytoplasm.
Sequence:
MTVLHSIDFFSSSSAPVAIEARAPQSAFPEHHHDFYEIVIVEEGAGVHVFNGNPYTLSRGCVCFVRDHDRHLFESTDDLFLTNVLFRAPDAFRFLSGVGHFLPRECDGVYPSHWRVNGQVLQQIKCLIACLEHAPKSDQVEDIALHESVFMQLLVKLWQGCQTQVGDDQEGRLYQLLDWLQNNYSEAVEWPELADRFALPLRTLHRQLKNKTGMTPQRYLTRLHLLQARHQLCYSDNSVTDIAYLCGFGDSNHFSTLFKREFSQSPRDLRSQL
The following text describes a protein:
Function:
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MAAANQVYSDAIRKTLEATLCLRSFPSEIIEKQSKPEIELNGYSSKTRQLVLSPIYLCRGEKEKCVIEPSINSTRISFSIKALDDVDRLIGEKFAKYLAVRADYFEILRRKPIPGYDISFLILDSHLEKYNVQGIINFIIDYVENIDKDLSDIKLNINTQARITAACFVGGLANQ
The following text describes a protein:
Function:
In vivo, this neurotoxin paralyzes about 50% of blowflies (L.caesar) one hour after intrathoracic injection, when tested at high doses (54 nmol/g).
Subcellular Localization:
Secreted.
Sequence:
MKLSFLSLAFAVIFVMAIMYAPQVEAKASADADADADAAASADALAKASAGMLDRILGAVKGFMGS
The following text describes a protein:
Function:
Plays a role in vesicular protein sorting.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MSTPAPPEDQARLLEDALIAVRQQSTLMRKCLDTPGKLMDALKCCSTLVSELRTSSLGPKQYYELYMAVFDALRYLSVHLRENHPVNHLADLYELVQYAGNIIPRLYLMITVGTAYMSIDGAPVKELMKDMMDMSRGVQHPVRGLFLRYYLSGQARDYLPTGDSEGPEGNLQDSINFILTNFVEMNKLWVRLQHQGHSRERDQRTQERKELQLLVGNNIVRLSQLVDLPTYKNGILAPLLEQVVQCRDVLAQEYLLEVITQVFPDEFHLHTLDQFLAAVSRLNPHVNVKGIVIGLMDRLSDYAEREAQNEEGEDRGQLEEEALANLLERVKLVKSAAETEEASAPTPEAPENGEHAETDVGSTDEPLNAEPSVAETEATVTNGDEVEPAKKHRGIPENVPLYEIFFGQVKNLVQAQHLPIQDTIALCVSLTTLALNIYPERLDYVDQILDYAHSKVKEHANSADLHAPPAQQSILALLQAPLKRYVSIFTALALPTYVPLFQSQTYPTRRAVAGEVARHLIKNQTHITTTANLENVLEVLKVLIKEGSQAPSGYPGVVQQRGRALETDETLEEQGWLARLVHLLQAEDNDTQFRLLQMTRKAYAEGNERIRTTTPPLITAGLKLARRYKAREHYDDNWQSQCSALFKFLHSAISTLYTRVNGAGAAELSLRLFCSCGQMADKTEFEEVAYEFFAQAFTVYEEAISDSKAQFQAVCAIASALHRTRNFGKENYDTLITKCAQHASKLLRKPDQCRAVYLASHLWWATPIASNGETEETELYRDGKRVLECLQRALRVADSCMETATSIELFVEILDRYVYYFDQKNESVTTKYLNGLIELIHSNLAGNQQDSASVEASRKHFMQTLEIIRSKEYEGIVLTPK
The following text describes a protein:
Function:
Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MEAQSSDISSSHEPGDTKPWEDLDDVLDLTGGAGQFSPTFPVSYPARHMEEKEEENEDEEEDEKSWKESLEASPVLEDPGSTSGSSPTPHSPPEPSAPTEEPERPPATCTAPSSSLAYTYLAQRLRKEDENLFPLPAASAHLMHLSADKIMEPSSTVSTGQEDFASVLLQSTASLSSLPSLSSKEHVQTVAFSTGLAANEALQEPTDNTYSASRSLIDTLETKALDQFKEEVIFSDKGYVVEHPTSQQETISEEHAKLYSQSAKEMFSGMLQSVAPPHEEFTDIKEVDYQYVDFKPFISSNSRDIGYEVKDVAEKLHVGRLNLESTAKHEEKSSEEKEMDISDDISPLTPEVLSDSTDYEMFATVEHSYPFSLGGSRVAGNKTDEKKIEDFEAQKTSVGFGLKVATVNPFYDESAQESEYVTTGATRVQVSTKAEGPTPDIVQEAYESEAYDTGISKLNYEPNIDLVQTAATSMQEKVSPTAQVPALLEDSVSSPVLPDIVMEAPLASTLCLETMALKPDISPVRIEPPARDEKTKAEPEKPPSYEEAVTEVLQDQGPAAAADLGDSKQGAVVKEAEAPYISPYISIACDLIKGTQSAASDFTEFSKFKQHEFDSQFMEPSDESSPDSELSEPSYKQWDSEVVRKETFTIKTESAMAQSFVIPEQKPGIDQKSEESSPSKPYLASFQPEIYVSKATDLFAKGLDTEISIPQERHLHMEEFDEGLYSSKLPGSKYSPVSESPEFRLSPEELTSKHEEIQTHIAKHPEDKLQKNKDKLDFLPENIEFTPIVQKADDFGKAASATHGGVDTTAKGASEVHEEKVTKPEPPSKKDEVSKLPKKESKAPSSTVPSSDFRNSVVDLIYWRDIKRSGVVFGASLFLLLSLSVFSIVSVLAYIALALLSVTISFRIYKGVLQAIQKSEEGHPFRSILESNLALPEDVVQKHCTVALNQVNRTVAELRRLFLVEDLVDSLKFAVLMWVFTYIGALFNGLTLLIVALISLFSIPVIYERHQTQVDHYLALINKNLKNTSDLILAKVPGLKRKSE
The following text describes a protein:
Function:
May promote auxin-stimulated organ elongation, such as hypocotyls, stamen filaments and petals.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MMNTKKLIKMFRKWQQRAALHRKRISFQRPSTRSTTVEKGCFVVYTADNTRFAFPISYLSNSVFQEILEISEEEFGLPTGGPITLPFDSVFLEYLIKLIKRRMDGDTEKALLMSISSARCSLQKQEQSTQQLLVF
The following text describes a protein:
Function:
Involved in the transport of copper.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAMPMPMPPPGPGGDAPPAPTMMPGMAMPMTTGMSFTWGHRAVVLFPRWPGDRAGVGMYFLCLLLVLALAALAEALSAASRRLDLDLDLSRSRGRRRRRRQQLLAAGVHAARMGLAYLVMLAVMSFNAGVLLAAVAGHAAGFLLARSGLLGSRAAAPEIDGAAAAAAATSNGSSLHPSSEPKP
The following text describes a protein:
Function:
Anaerobically catalyzes the stereospecific hydration of beta-myrcene to (3S)-linalool and the isomerization of (3S)-linalool to geraniol. Is thus involved in the initial steps of the anaerobic degradation of the monoterpene beta-myrcene. Also catalyzes the reverse reactions, i.e. the isomerization of geraniol to linalool and the dehydration of linalool to myrcene. In this direction, the formation of myrcene from geraniol may be seen as a detoxification process for the monoterpene alcohol. Shows a relatively broad substrate specificity and can use various geraniol and linalool derivatives. Substrates required a specific alpha-methylallyl alcohol signature motif. Neither the monoterpenes alpha- and beta-ocimene nor the monoterpenoids citronellol and nerol can be used as substrates.
Miscellaneous:
MISCELLANEOUS: Requires DTT as a reducing agent for full activity in vitro.
Subcellular Localization:
Periplasm.
Sequence:
MRFTLKTTAIVSAAALLAGFGPPPRAAELPPGRLATTEDYFAQQAKQAVTPDVMAQLAYMNYIDFISPFYSRGCSFEAWELKHTPQRVIKYSIAFYAYGLASVALIDPKLRALAGHDLDIAVSKMKCKRVWGDWEEDGFGTDPIEKENIMYKGHLNLMYGLYQLVTGSRRYEAEHAHLTRIIHDEIAANPFAGIVCEPDNYFVQCNSVAYLSLWVYDRLHGTDYRAATRAWLDFIQKDLIDPERGAFYLSYHPESGAVKPWISAYTTAWTLAMVHGMDPAFSERYYPRFKQTFVEVYDEGRKARVRETAGTDDADGGVGLASAFTLLLAREMGDQQLFDQLLNHLEPPAKPSIVSASLRYEHPGSLLFDELLFLAKVHAGFGALLRMPPPAAKLAGK
The following text describes a protein:
Function:
Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
Subcellular Localization:
Endomembrane system. Golgi apparatus, Golgi stack membrane.
Sequence:
MCVVYNRRFQETEKTIVVSKEYTHKESLKHGLKVRSLIRSVIVKSFQIQQLLNHDMNKLAEKNKDLVQRLVNWDRLLVPLENSLINEMTLLNNEDEEGDRYKLRELNRRAQHLIQHTQNQKDCRRAKKLFCNVEAKCGFGCLVHHYGVCLFLAIGTNRVMQWDLKAITDYPGLDEVFMPLSETCNNITGGKEAPEWYSEKSSNPTPVDTEVVKVTLIGSRDRQTPFAPMTIPEEFYPLVEPIHGDPLVWWAGQVQSYLMRPKAWVTREVQIIKQDIGFKHPVVGVHIRRTDKSNEANFQRMEAYMDPVANWYDKYVINNDVTNITKLVYVATDDLEYMDMLRNLYPEFTFITNQQSTSHADTSSRLSSDGLKGIVTDVHLLVECDHFVGTFSSNIGRLVYEMKQQYDSDPTFTTTNIDHAYRYWGQAIQLHKAVMDHKPSLGFCKRAAPDMRQIDLSKMELMCEIEIKVGDIIEVSPESYHGYRSAGKNVRTQMFGAYPLFKVKDIIKTAPYPSFYRTKSFEVE