lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (By similarity).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MLSLIKLQRVFNVHQVPKAFHEDGIISGYRHPRSSATECVWSLFQLTNETLNVWTHFLPTWYFLWKLMTVLLMEDVWNEAYTWPLLVFLFSCCVYPLASSCAHTFSSMSTRARHICYFFDYGALSFYSLGSAISYSAYVFPDAWLSSSFHAYYISVAVFNTVLSTSLACYSRLGLPLLHYSHDIVERFSERQCPRMSKVLRILAFAYPYLFDNIPLFYRLFVCVGEGCTDNEANSVHVQHTLLAFLTSFLFATHLPERLAPGRFDYIGHSHQLFHVCAIIGTHFQMKAIEMDMGLRRSQLLASAPAISFNNTIGAALLCVSVSLGIICVYSLPLLYSSNPKNTANKE
The following text describes a protein:
Function:
Slow-binding inhibitor of serine proteases. The inhibitor rapidly binds to the protease forming a weak enzyme-inhibitor complex, and this is followed by a slow isomerization forming a tight-binding enzyme-inhibitor complex. Active against subtilisin A with a dissociation constant of 0.18 nM. Active against perkinsin. Not active against thermolysin, papain or pepsin.
Subcellular Localization:
Secreted.
Sequence:
MKVAVVVALLCFVCYTAAETCSADGDCKNTICDASHDLECHRGQCTCVNHATACSSAADCSGSCTIFGRHGRWHCVDAKCRCFFV
The following text describes a protein:
Function:
Involved in D-lactate, but not L-lactate catabolic process.
Subcellular Localization:
Mitochondrion.
Sequence:
MASLLRAAATLGLFPRRGYCSRGAQGELSKGFVEALKAVVGSSHVSTAAAHREQHGHDESMHRCQPPDVVVWPQNVEQVSRLAALCYSQGLPIIPFGTGTGLEGGVCAVQGGVCINLTHMDRILKLNPEDFSVVVEPGVTRKALNTYLRDSGLWFPVDPGADASLCGMVATGASGTNAVRYGTMRDNVLNLEVVLPGGRLLHTAGLGRHFRSGLWPETHRLMAGHLPSVSPGSRKSAAGYNLTGLFVGSEGTLGLITAATLRLHPVPEATVAATCAFPSVQAAVDTTVHILQAAVPVARIEFLDEVMMDACNRHSQLNCPVAPTLFLEFHGSEQALAEQIQRAEEIAGHNGASLFSWAKEAEERRRLWAARHSAWYAALALRPGCKGYSTDVCVPISRLPEILVQTKEDLKASGLTGTIVGHVGDGNFHCILLVDPEDTEEVRRVMAFGEQLGRRALALHGTCTGEHGIGLGKQQLLQEEVGAVGMETMRQLKAMLDPQGLMNPGKVL
The following text describes a protein:
Function:
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
SSISAETNNKECALCGFVIDYVKGQLLKNKTETYILDKLEKVCLLVPAPLQPTCRLLVTLYGVPAIKMASSKVNTTVLCELVDLCPTPTPTPTKTVQNVQVGDTKCTICDFVVGEVEKYLSGNATEAQIITFLNKDCKIFGAFGTTCQSLVQAYVPTIINLLENNQSPDTVCAEIKLCTSRLSKKV
The following text describes a protein:
Function:
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
Sequence:
MGKGDARTRSGRGRGRGRGGGSGGVCSTSGFHNNEPPAHPCSVPLAMWDFEQCDPNACSGKKLYRLNALRLLRLSEPFHGVVLTPSATEIVSPADRGIVLQNGAAVVDCSWKELDAVPWRKMRMSAPRLLPLLLAANPVNYGRPSKLNCAEALAATLAIVGLTDDARSIMAYFSWGASFFDVNRELLAGYQKCTNSAEIAAFQDKYVEAELQESEARRGLDLDSIDLSDARPLNERRGRLKNRREWQQPSCSEDEEENDKAGEDDNSDEGADARVSEEDEDRRESECAAADSTEETA
The following text describes a protein:
Function:
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity). Also catalyzes at a very low rate the synthesis of thiamine triphosphate (ThTP) from thiamine diphosphate (ThDP) and ADP (By similarity).
Subcellular Localization:
Cytoplasm.
Domain:
Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
Sequence:
MEEKLKKAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYLDSLK
The following text describes a protein:
Function:
Involved in iron homeostasis within the mitochondrion where it is involved in the assembly of iron-sulfur proteins. Together with BOL3, required during the last step of iron-sulfur protein assembly when the iron-sulfur cluster is inserted into the target protein. Required for protecting iron sulfur clusters from oxidative damage.
Miscellaneous:
MISCELLANEOUS: Present with 11300 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion matrix.
Domain:
The CxxC motif may bind a [4Fe-4S] cluster.
Sequence:
MFKSVAKLGKSPIFYLNSQRLIHIKTLTTPNENALKFLSTDGEMLQTRGSKSIVIKNTDENLINHSKLAQQIFLQCPGVESLMIGDDFLTINKDRMVHWNSIKPEIIDLLTKQLAYGEDVISKEFHAVQEEEGEGGYKINMPKFELTEEDEEVSELIEELIDTRIRPAILEDGGDIDYRGWDPKTGTVYLRLQGACTSCSSSEVTLKYGIESMLKHYVDEVKEVIQIMDPEQEIALKEFDKLEKKLESSKNTSHEK
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MQNTKQQQLYSQLRRLVENGHSEPTTDSLEQAVKVCDKLLAISDTDVDALRTKLVALVKLERYADASNALSTHKLSTKGSKFKNMAELYFESAYCLYRSNSLEDSLKLIQQALLADEIQKSPLYTRFMHLKGQVLYRLERFNECISSVYKPLLASANDHSDTYRVEILANILAAEAAQVLVGSEMDTDDGADDANTESPTFEILYNRACKAIGKHNYDTAEKLLYNAQATCTKSMNADGYSKEDIQKELVVINAQLAYINQCQGRFQKALDQYTCINQSMSVEKSIAAVIHNNLMAIRGEHYDLFESAKVHKNFMTSDVLLKLNAGQRNVMEINNALLSIYLGKNGQATKQLTVLKEKYPHIDRIELAFAGLQFRQKKSKDVTTMLAFRNQLEKIVEQFPSSASAQLTLVQVLLNLGYYEDVVNQVEKMLEMDVFAMYRPGLVSVLSWVYGKMGNSLMALKVLETAAKDKFIKDMSLLAQLAAFKLRLGQYEAASKDYLELVQFDPLDVRAIAGLVISYSHLDSSLAEEYAKQLPTPSISRSDQGDESMHALKMDADALELAVMKRKMNQQLRMQTAGKNGDATKNKADKPKTKRKRKPILPKVVNPDIQPDPERWIPKQFRAAFAKKGKGKKDMLRGSQGVNMEGGGIGGTGSARIAGISRSSTLAETESTGSSTVNAQPSPPTTPKPKQKKRK
The following text describes a protein:
Function:
Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs.
Sequence:
MSKSRRVFLSIQGDDDFWGNGDQLEGKTLSSIKQQESKKMDDSVEGMEEEKYFFRQSKLGRQNLERLHEKEEQECEEERLDWSEKVDSEEEEEDIQEQDEIITEGKETEMFDSGPETDQKMPVDPNEGFYNNYRSYFSGRPEMLFLIRSIDESATDYYEKPFIDLYETTRKRLEMYPNTELNQILRCACNPNAGGGADYRVRNKHAVVVSNFREPDRRLGRYSKYYYHHNVGPEVYSRKVFVGGLPACVKEMDILHFFSRYGRLQVDWPSKHYGCKSDSDPSVYNEPSFTPPTSHLGLSSPPFGQINPFMTDCPPAPSDLQMSRHGSVDGGGGGFPTHGMSMRNIGFGGGSGPRSTGEGEKKQQHLGYVFLLFEKERSVRDLVTECFEEEEGLFIILESAIEPIRVQIRPWLLADAEFLMDFNVPINTKMVAFIGGVPRPLKAVELAHFFEQTYGNVVCVGIDIDNKFKYPRGSGRVAFSNYHAYVQAITDRYIVLDHEDIHKRVEIKPYFFHNQSCEECSSRYHRQYAPFFCPSLECFQYYCEPCWHKMHARPSRFHHMPVVKGI
The following text describes a protein:
Function:
Acts with rhp54 to repair meiotic double strand breaks via homologous recombination. Involved in meiotic DNA recombination.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MKRRATFQCPLIESTIKHQSTNYTKTETATTSHEVSENANEHKGKSNIDINKIAYYNVVWRKITMKKHKTWEGDGFLVREDSNLTLYNSDFTRLGSCHSRVPQIKEGELLRISGKEISIEKEISAESYEAGTHIDDSLRDVHMPEMKRKFKPPLRPNTMYQTISALPKPRHDPTVLGALVMSRPKTWDPRTHVDVVIDPFLSKHLYSHQREGVSFLYDCLLGMEGKCGYSAILADEMGLGKTLQTITVVWTLLKQSYYANRSSTINNAMVVAPVTLLKNWENEFYNWLGHERIHVYIARCAEDFQEFTSNKTYSIIITGYETVCTYLRNYGCGIDIDLLICDEAHRLKSMSSQTWITLNKLKTRKRLLLTGTPLQNDLSEYFSMVNFIIPGSLGTPNSFKAQYERPILRSRSMNASSRDISLGAARLQRLFEFTSNFTLRRKANILAKHLPPRTDIVLFIKPTHQQENVYGHVLDGFKSSVDQKGYYLKILTRLSKICNSTILLRNEKENFLSTELQDKHVFEQENMLLSSSKLQILAALLKSFQRGCQKAVIVSQYKETLELIELFLSILHVRFCKLLGSTPFSERDLIVHNFNTSSFKEFSVLLLSSKAGGCGLNLTGSTRLIIYEPSWNPAQDLQALSRIYRSGQKRPVCIYTFLSSGMLDERIFIRQNTKQGLSSSFIDSDASQKKNFFTGEDIKTLFSYSKTETCLTYELAFDSDEIDSLTKKKDPLTKIDHTIDSPNTKEKDKEISSWKKASEYMDTNLGKKCPENAFQGWTWQFPNDLSIMNGVEDYIPLEPLPINCLMHKKFE
The following text describes a protein:
Function:
Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
MDLGFLWVLSFYWLISRGPCVLGEKGPVDMASLISSIIQHSSPRLRPVRHWDTTLTVQLDLRLYSILDVNEKEEKVSLHVLCTQRWKDEFLSWDPAEFSGLSHFTLPVSSVWTPDIIVREAVSVGRVEADAFVSVNSTGWVQHIEPLLLVLRCDLAMFHFPFDSQRCNLTFGPNLHTVEDVELVPERSAGAVLNASRQSIRHGEWELLSIRTYSFTETQGSHSYSRITFQVEMGRSSLFYVVNLIVPSGFVMLIDLAGFAIPVESAERIPFKVTLLLGYTVFLVLVNDLLPPFRENTPILGVYFVVCLAFLSLSVGESMILLALGKPDILHHVPPLPRLATLFFPDWMKNKKWAETQTPLDSEFRDKSRLIRDLQRAYRLGEGQGQGQGSEARSTLADAMQALEAELWEVSEELRILTHRGSRRRARLQLMETTDWLCFCVYVAMLAAFLLILMVFWMLGH
The following text describes a protein:
Function:
Plays a role in the toxic effects of organotins. Plays a role in endosomal maturation.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein.
Sequence:
MSIMDHSPTTGVVTVIVILIAIAALGALILGCWCYLRLQRISQSEDEESIVGDGETKEPFLLVQYSAKGPCVERKAKLTPNGPEVHS
The following text describes a protein:
Function:
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. First enzyme of the fatty acid beta-oxidation pathway.
Subcellular Localization:
Peroxisome.
Sequence:
MYCPKAYENEKKNEDLEFERSQSTFSVSELNFILNNNDHNIINIKNEIKKFIDNDEIISKPQEIHFLSREEQYKRALYVSSKLIEIKKRFGEIGRDQYYQSLFEEIPFVINDIVFACAFKSLASDEQMNRLYSKFENYQYFGSYSQTEIGHGSNVQGIETTCTFIKETGEFELNSPNLTSTKFWIGGLGKLATHTIVFAQLLIPSSIDGKLKNYGPHPFILQVRSLDDHSPLPGVTVGDIGPKLGFNSIDNGFLRLDHVRIPRENMLSRFFRVNEQGEYEKPKHPKLIYAGMVGVRSSMIENSFVSLSRAVTIAIRYSTIRKQFKSNRLDKQEKKIIEYSNQMNRIIPYLAQTFAYFFTGKRFSIEFDQMMKAVKHNQDTTLLSELHANSSGLKSLMTQSTSDGIESCRLSCGGHGYSQFSGLPYLWSNYVHMSSAEGESNLLPQQTTKYLLTILRKVLSGGGGSSDTTTADDDNKPIGKSVKYINDEFQSSFENINQFIQEKGLNSIIHPDSLLQLFKHRSFILIKSIAESIQEQMSNGNKDIPQIWSDLNVEINHCSKAHCQLYVIQSFYDQILLLSSNSSSCSSSITTVLIQLLQTYSIWIINSNLVDFLQDQYVELSQIDFLKKSLINFYKLLRPNLVPLVDSFDLCNTTLGSALGSYNGDVYSTLYKWASTQPFNKNSLPLGFNETIKPLINSKL
The following text describes a protein:
Function:
Part of a high-affinity transport system.
Sequence:
MENKPILSFEKVSIIYKKAPLLQNISFKVMAKENVCLLGKSGVGKSSLLNSVTNTKIVKSGLVYFDGVASNKKEYKKLKKQCSYLDQIPNLIDTDYVYEAILRSAKQKLTWLQKLICFEPKWIKDKILAILKEVNLNDYVSCIIKDLSAGQKQRVEIAKLFFKSPKLLLVDEPTTGLDPLTASKIMDLITDFVKREKITLVFVTHDIDLALKYSTRIIALKNHALVLDRLTEKLTKEQLYKIYDN
The following text describes a protein:
Function:
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex.
Subcellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
Sequence:
MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAILNPLCQVDYRAKLWACNFCFQRNQFPPAYAGISEVNQPAELMPQFSTIEYMIQRGARSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSCEGISKSYVFRGTKDLTAKQIQEMLGLTKSAMPVQQVRPGQPQEQSAVSSRFLQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELKTPIRSWHDIEKDNARFMKKATKHYEMLANRTATNGHCIDIYACALDQTGLLEMKCCPNLTGGLMVMGDSFNTSLFKQTFQRIFSKDFNGDFRMAFGATLEVKELGVGGTSQWKICGLDPSSTLGIYFEVVNQHNAPIPQGGRGAIQFVTQYQHSSTQKRIRVTTIARNWADAQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVIYLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFLLSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAS
The following text describes a protein:
Function:
Proton-dependent efflux pump (By similarity). Confers resistance to a broad spectrum of chemically unrelated substrates (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MQRIIQFFSQRATTLFFPMALILYDFAAYLTTDLIQPGIINVVRDFNADVSLAPASVSLYLAGGMALQWLLGPLSDRIGRRPVLIAGALIFTLACAATLLTTSMTQFLVARFVQGTSICFIATVGYVTVQEAFGQTKAIKLMAIITSIVLVAPVIGPLSGAALMHFVHWKVLFGIIAVMGLLALCGLLLAMPETVQRGAVPFSAVSVLRDFRNVFRNPIFLTGAATLSLSYIPMMSWVAVSPVILIDAGGMSTSQFAWAQVPVFGAVIVANMIVVRLVKDPTRPRFIWRAVPIQLSGLATLLLGNLLLPHVWLWSVLGTSLYAFGIGMIFPTLFRFTLFSNNLPKGTVSASLNMVILTVMAVSVEVGRWLWFHGGRLPFHLLAAVAGVIVVFTLATLLQRVRQHEAAELAAEK
The following text describes a protein:
Function:
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
Subcellular Localization:
[Phosphatidylserine decarboxylase beta chain]: Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side; [Phosphatidylserine decarboxylase alpha chain]: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain.
Sequence:
MMPLFNVLRSARMLPAVSKKVVSPPMMLRSVRELTNQSKNVYATKEVIIGASQKKKRSWVKWLSVSTLIIGGASYVGYLFTPDWREIVDSKHYYSNWKIRVYLSLPFNTASRVIGGLANQEIPVWLREHLLGGFARMYDCRMDDCVDPDFKNYPSFAAFFNRKLKESTRPISASPLVSPADGTVLHFGKVEDNKIEYVKGHDYDVDKFLGDVDLPQKDELDLYQVVIYLAPGDYHAFHSPARWVANQCRHVPGLLLSVRPTLLSHVPHLFCLNERVVLNGSWRHGFFSMSAVAATNVGDIVVDAEPSLRTNIVRRKTQKIMNTETEIHAPYVSGERVGEFRLGSTIVLVFQAPPTIKFAIKAGDPLRYGQSLVADGV
The following text describes a protein:
Function:
Involved in UV protection and mutation. Poorly processive, error-prone DNA polymerase involved in translesion repair. Essential for induced (or SOS) mutagenesis. Able to replicate DNA across DNA lesions (thymine photodimers and abasic sites, called translesion synthesis) in the presence of activated RecA; efficiency is maximal in the presence of the beta sliding-clamp and clamp-loading complex of DNA polymerase III plus single-stranded binding protein (SSB). RecA and to a lesser extent the beta clamp-complex may target Pol V to replication complexes stalled at DNA template lesions.
Sequence:
MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLLIQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIVIAAVDGEFTVKKLQLRPTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR
The following text describes a protein:
Function:
Catalyzes the N-acetylation of L-phenylalanine and L-methionine using acetyl-CoA as acetyl donor in vitro. Cannot accept L-tyrosine as substrate and propionyl-CoA, succinyl-CoA or (S)-methylmalonyl-CoA as acyl donors. Is also able to acetylate and thus detoxify several nonhydrolyzable aminoacyl adenylates, but not the processed form of the peptide-nucleotide antibiotic microcin C (McC). When overproduced, provides complete resistance to leucyl sulfamoyl adenylate (LSA) and partial resistance to alanyl sulfamoyl adenylate (ASA) and phenylalanyl sulfamoyl adenylate (FSA). Therefore, may protect bacteria from various toxic aminoacyl nucleotides, either exogenous or those generated inside the cell during normal metabolism.
Sequence:
MSEIVIRHAETRDYEAIRQIHAQPEVYCNTLQVPHPSDHMWQERLADRPGIKQLVACIDGDVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMREMIEMCDNWLRVDRIELTVFVDNAPAIKVYKKYGFEIEGTGKKYALRNGEYVDAYYMARVK
The following text describes a protein:
Function:
Potassium transporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MENRQPKQLVFKGRQETALELAPSNCEADAEPPVLHIAQVASISDEDWLHDHDLEDALVGQKAKASASWGVFFGLTYTSVGVVYGDLGTSPMYLWQTCFSFPATESDIVGALSLVLWTLTLIVVFKYVVIVLCANDQGEGGTFAVYSLLCRHAKITPFGNLHDSDKGLSQYSKEGAKERRRLPKKLAAALEGSPLLQNVLLTFVLCGTCALAGDGVLTPPVSVLSAMTGLQVPTVLLNADGSTKISNGVVIGATCAVLIGIFLSQQFGTSKIGYVYAPILIVYFVVNASIGVYNISKWEPSIFKAFSPSYGIDYLVRNKFNGWKSLGGICLAITGVEALFADLGHFNVSSIRASSMFLVYPSLLLIYLGQGAYLSKNPGDVSQAYYKGIPTPVYWPVFVLAMLASIVASQAIIAGTFSVLAQSARLNCFPRVKVVHTSKVVEGQIYIPEVNWILMVLGLACVLGFSLPQPSDQPVNGEALGNAFGIAVMFVMVITTCLVTLVMLLVWNVRPLLAAAFFGFFFVFEMVFLSANVYKVEHGGWFPLAIAVIVFGISYVWHWGSTQRCLHSAKLGSQLEDVIVAEKNEIEEAPQTAPSDSVKVCLKSSGHRIYAARGAALFYCDTLHHLPPIFAFSLEAMPTVHEITVFLTIRQVPVPHVLQKERLLVKPMAYPGFYWVLARYGYLDQPNHSAAFARQVLKTIAHYLEHGSSCPDLQALDPDGQDPTWSLSRAASRKLNPRIALAGTQLNGTEQNGMPDLTLTDASKALGLSPPPSEASFENVESKPPLFKPASQKPANTTIDENGISADEQDLLPDDTGVEISDYARQVKLLKDAQRQRILYLKTRSVVRAAKDSSVLRKFVLESAYNGLLNLSRSPAHILNIPYSQLLELAMVYEL
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MAPATQQVFIDGTFADLAQELAEYLQIGPEVQPLLEENQKDEALKKLVTASASLNSSPEKEFTAAYNLLVYLCVQSPNVNMYLPKICDNLARPITSSPLNGPGLALNVMTTIFNLLQPDNETRFNVFQAVLKLIKTSGNYEMLRPQLKKLDTWIVEWGIEEEDQRKLFEMISEVADDSGEEEESYQYILKALRTFDGKDEKAIASEEAQKLAIKALRTALPSNTHFDFHDLTSLPAIQALSDSHAIYSELLEIFAEKELEDYNDFLDEHDGFVEKENLDNSKLHRKMRLLTLASLAASTHTRELEYRRISKALQVAPEDVEMWVIDVIRAGLVEGKLSQQKQVFLIHRTTYRVFGEKQWREVATRLDQWKESLRGVKEVISRERQAAESQKEKEIQEADKKVSGAQGMNAGRRRDNMVEMGTD
The following text describes a protein:
Function:
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1.
Subcellular Localization:
Nucleus.
Sequence:
MTSQVVPLSTFVQHLESCEGYEFRTMIKMLASPAYAKQQLLKDELSVFMAKVLKLLRSKDDYQVWKGCHIATVFCTYNPVVLCSFGGELMGILYRALEDATKYYGDSVQTEQRKVMVRALVKTLDTLMDLIRGKPSLTREALTPHLSAIIPMLISFGRCEPNLSLPVIKKLLSKHSTTFRPHVGKLKQLLTELYGHYQSLDPVTRKVVCDTAAYLHLTQKPGNNANEHQAHHKSFPDEHWRAGLFSVLSQFGPVVRLWGEILDIGSDENLARLLETLPRDTANDTSPLLPALTVDINKPVTLWHISARLEQLTDMVESFIRLPTLFPTRIPLGELVKVSEILLSLTTNYLPLKRGLRRDAALTGSIRSALPETQLQGIRLLRCLSDHIGKNLITYMPAILSSMELFIPLKDKKTSIDYQKCVDLQNGLLQLTALMNSIAQHLGHKVEEMSLAIKLVDICAYIIEHKQNLDSAFSSTSGTAKAAGGAKKKEYKAKTGSMSDLFSHPHKFLHPVPLENYTVVNTYYNMALTHWKLPSTQQAKITKYCIYYSLSFKEKLGYIPQTFIELLNTIVLFPGKDRFSILPIAVHLLKETGDPVFDVLCNPKLPLEMIQIRRQPTSSEDDTATSEAEEYAAPADQDDEHLSDDEHTTVDDGVATNAVMGLNNLVSSETLRSEQDSALETQHPEQARTSNLVPDEASEGREDARIFKKRSSSDEQDPPSKRTRAVAAQTPVPAAVPVDNGEPESDDGSDFEIPEIELSDADEE
The following text describes a protein:
Function:
Self-assembles to form a helical, filamentous nucleocapsid mesuring 1980 nm in length and 24 nm in width. Together with capsid protein 2, wraps arounds the DNA and maintains it in an A-form. Capsid proteins probably maintain the DNA in A-form by non-specific desolvation and specific coordination of the DNA phosphate groups by positively charged residues. This certainly protects the viral DNA under conditions such as the extreme desiccation of its host.
Subcellular Localization:
Virion.
Domain:
The N-terminus projects into a DNA groove.
Sequence:
MAGRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Sequence:
MATPTQDIFPLLDLEELVICLQSCDFAMATEEHIARPTSQYVITLYKQIIENFMGISPEQVLAEQLSSRQNTEGNDESTSVDMFDGPYRETLQMLTLNKICYKFFENVGINDFNIVDLYKPEAYRTRRLLSAVVNYARFREERMFDCNQFIIQMEEMLDELKSKFDDFNYLKAQLTAIEDDDEKTPGELEDLLQKNKVLETNLKKLTILQEKLSIDYNNYKMKKQELLRELEKNSFTLIELESKKERLMNYNDDDQDLQNSLNNSIDRLTEEKKKQIGYVSKLEGNVSNLKVTVDTLEKAIEHIYDILRLLSTDLQESHRAELNIEGIKGPLTEKRTRLKNLLESNVIYKYDVLKEQLNVAETEYQRINEEHYRETLENKKLIQELEGKYNNIIHNKMQEAEVYIENEITEKKIKILQSELNDIQIQFNNEIDNIELHYSTLVGHINNYMKKLITALNNH
The following text describes a protein:
Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Sequence:
MDMLLNPLNRRHRLRHDIPVVPGAFPLVGHLPAVVCDLPRLLRRAERTLGSHFWLDFGPAGHLMTSLDPDALALLRHKDVSSGLIEDIAPELFGGTLVAQDGIAHRQARDAIQAALLPKGLTLAGIGELFAPVIRARVQRWRERGDVTILRETGDLMLKLIFSLMGIPAQDLPGWHRKYRQLLQLIVAPPVDLPGLPLRRGRAARDWIDARLREFVRAAREHASRTGLINDMVSAFDRSDDALSDDVLVANIRLLLLGGHDTTASTMAWMVIELARQPGLWDALVEEAQRVGAVPTRHADLAQCPVAEALFRETLRVHPATPLLVRRALRELRIGQQRIPTGTDLCIPLLHFSTSALLHEAPDQFRLARWLQRTEPIRPVDMLQFGTGPHFCMGYHLVWLELVQFCIALALTMHEAGVRPRLLSGVEKGRRYYPTAHPSMTIRIGFS
The following text describes a protein:
Function:
Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MKSRRAGPPDGGYGWVVVASAFCVTGLTGAVLKNYGHFFLDIQDHFGVLTSTTSWVTSTTIVMFHVGAPAASALTAWLSQRVVIMVGGLLCTFGMLLASLDLSLPWLYFSMGILEGIGLSFSWVSAMSVVNHYFARWRPIAYAITSSGECVFAFIFSPFFKWLIEMYTWRGALLIIGGLQLNLCVCGALMRPLDSTESTAGLETDADSFQPKKKVIFQLSLLRKPELLLYILFAIFAAVGFYVPTLFLVPFANSLGIDKYWPALILSVLAVADLAGRLFSGWLANMRFFRNLQQLTFVATLLGVVLLLLPISQKYWVIMILASLYGFLFGCVVAVHVTCIVDIVTLEGFDSGLGLFMMFRSIGGFIGPPAGGWLVDHTDDYGSAFYLAGCCLISSAVFVLLVDRLVQRSKAVGEEVNKPEEPETAKV
The following text describes a protein:
Function:
Protease inhibitor that, together with SCP1, controls mycorrhiza establishment and arbuscule development during root colonization by arbuscular mycorrhizal (AM) fungi (e.g. Rhizophagus irregularis), probably by degrading SCP1 in the apoplast of the periarbuscular region.
Subcellular Localization:
Secreted. Secreted, extracellular space, apoplast.
Sequence:
MSMRLSIRTLIILAHVCLFITTTTIAQFVLDTVGEPVEGDEEYFIRPVITNKGGRSTMVSRNESCPLHVGLELTGLGRGLVVKFTPFAPHHDFDDVRVNRDLRITFQASSSCVQSTEWRLGEKDTKSGRRLIITGTDSATNGSYGNFFRIVETPLEGMYNIQWCPTEVCPSCKFECGTVDMLNENGKILLALDGGPLPLVFQKE
The following text describes a protein:
Function:
Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling.
Subcellular Localization:
Cell projection, cilium. Cytoplasm.
Sequence:
MSQFTNEDEALLQSMLRQLLQSVKEKITGAPSVECAEEILLHLEETDENFHNYEFVKYLRQYINNTLGSVIEEESEKCTSTQNQTEISGYDTLVQHVTKKTRESKQYREMMHALKNVMMVVVESLINKFEEDRMCNKELDSKSKKKCQSDYYTDNYSDSDSSFNQSYTFMSQEQLQLLVEKLDPIQPKEVRQEALQMLCLSPPSDVLNSECWPNLRKHLMMSLSDPDAIFSEKILRFYAKTFSSSPFNMAREVYTSLAQHLEFYFFSGEYSLRISSGLDVSNADVNHILKKVRLLNEYQKEAPSSWIRYPEKYMEEIVESTLSLLSVKHDPNHPASPDFLSPIYFLALLDIKAMWFKKWTHAHYSRTVILRLLEKKYKSLINAAVQQCLDYFEYCKAAVSKTPRVSGFSQQHLNNEQKFFYTGSELQYIYFVHSLCLLGRLLIYKQGRNLFPVHLENKKDCISLTDLLVLFARLIYYSPSYSKEALTAHTDNYSPASLVMEILQVFCDQTGCAADCLYTDAVMDALLDPLQSLLNGTEVYINCLETTLIDVADILARIAAAEDGLPVLLYGGSKNSAKESSPTAVHVIVQFTKKLLHDDISLLSGSELLQVVKGAFIFVCRQMYRTCEGLQMLIPYGLHESIGEAWKKASLLSERVPTPVTGADCTSSISLDSKNVLLWEETLLDALLNFSATPKGLFLLHSTGAMSDCVSFMFNSLSKKHQTNEREEFGNGVIVAQMATTPTAAVALQSSGFIKAFITELWALLECGKDDVRITQPKSTPVDPIDQSCQKSFLYLINLLTYPAVFELLSEQDIPNKPMYSHREVPTDIINVIDRIIIVNSEAKIHSLFNYEQSHIFGLRLLSVLCCELNTLLLLETQYKVSQVLLTAQEENVTEASEGPGDFIVDSLSVERNHVLVRINLIGGPQERILPLRALEKGSDPYPWPMFSSFPLPKCYLAEVPRKADFRQDKDLDELISILQNPGGQTEWAEICRRQFCKIMKTRPDIISGAILAELIEKFVLHLSESRSNCYFSIGRYEATDVDMKKESLSSVQQLGIEMTVRYGKYLNLLKEHAENELCFVLMNCEQFLKQQQRTVVSSLRCLQGRYAGYDWFASSVFLIMSGDGEKTLTFLQQFSHLLVSAFLWIPRLHMSMHLPITTVESGIHPVYFCTAHYIEMLLKAELPLVFSAFHMSGFTPSQICLQWITQCFWNYMDWSEICHYIATCIFLGPDYQVYMCISVFRHLQQDILKHTEAQDLQVFLKEEALHGFRVTDYLEYMESLELIYRPVLLKDMRNIGVQST