lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a role in xanthan depolymerization pathway by cleaving the linkage between the terminal mannosyl and glucuronyl residues of the side chain of xanthan to liberate pyruvylated mannose. Is highly specific for pyruvylated side-chains of xanthan and is not effective with hyaluronate, chondroitin A, gellan, heparin or pectin.
Miscellaneous:
MISCELLANEOUS: The 99 kDa precursor is converted to a mature form (77 kDa) through the removal of a C-terminal (22 kDa) fragment without any loss in activity.
Subcellular Localization:
Secreted.
Sequence:
MLSGILIAALLMTLWGGWQPDIAHASDEFDALRIKWATLLTGGPALDPADSDIAARTDKLAQDANDYWEDMDLSSSRTYIWYALRGNGTSDNVNAVYERLRTMALAATTVGSSLYGNADLKEDILDALDWLYVNSYNSTRSRSAYNWWHWQLGIPMSLNDIAVLLYDDISAARMATYMDTIDYFTPSIGLTGANRAWQAIVVGVRAVIVKDAVKLAAARNGLSGTGIFPYATGGDGFYADGSFVQHTTFAYTGGYGSSVLETTANLMYLLSGSTWSVSDPNQSNVWQWIYEAYRPLLYKGAMMDMVRGREISRSYAQDHAVGHGIVASIVRLAQFAPAPHAAAFKQIAKRVIQEDTFSSFYGDVSTDTIRLAKAIVDDPSIAPAAAPNLYKQYAAMDRAVLQRPGFALGLALYSTRISSYESINSENGRGWYTGAGATYLYNQDLAQYSEDYWPTVDAYRIPGTTVASGTPIASGTGTSSWTGGVSLAGQYGASGMDLSYGAYNLSARKSWFMFDDEIVALGSGISSTAGIPIETVVDNRKLNGAGDNAWTANGAALSTGLGVAQTLTGVNWVHLAGNTADGSDIGYYFPGGATLQTKREARTGTWKQINNRPATPSTAVTRNYETMWIDHGTNPSGASYGYVLLPNKTSAQVGAYAADPAIEIVVNTSGVQSVKEKTLGLVGANFWTDTTQTADLITSNKKASVMTREIADERLEASVSDPTQANNGTIAIELARSAEGYSADPGITVTQLAPTIKFTVNVNGAKGKSFHASFQLGEDTSGPVDPGEPELPSVIVDNADSAGVTRTGTWKTASTQTDRYGANYLHDDNAGKGTKSVTFTPNLPIAGSYEVYLMWPAHFNREDAVQVDVGHASGTTRTAVDQRSGGGVWHSIGTYEFLAGSGGSVTIRNDALGSPDGYVVADAVKFVAVG
The following text describes a protein:
Function:
Receptor for the ascaroside pheromone icas#9 which suppresses exploratory forgaging behavior. In response to ascaroside icas#9, may furthermore play a role in the expression of genes in the TGF-beta signaling pathway, such as daf-7, and in insulin signaling pathway, such as daf-28, which may in turn contribute to exploratory behavior.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, cilium.
Sequence:
MVLRNLTAMAIYDQTFVYSSDDALAGMVVSMECLTGLFLLVAVIIGCFRIAALKSPFGILMINQNCAQLMACINSGSFSTLGVLLNIKPVLSISYLFGNFSIFLLPVILISFLLMSFNRFCACFFPLRYQNLFSSSMIRTFIVFNWLLSLVAGSYLVVVRECNFVFYHFGWLFAGSVSVKCGTLLSLYSISIQTVLSITIVGLDVVTLVALMAFRSKVYQSHSVEVRRRELSFSGQVIIQGAVFLCHGAWYDMGHAILPGNDDRWKFFFTTSFSSNLLHVFDPVVVFAFNKEFRRWLFRNFNVPTAQKRIVTVVSAHNT
The following text describes a protein:
Function:
Required for vacuolar assembly and vacuolar traffic.
Subcellular Localization:
Vacuole.
Sequence:
MSSSSHSSLSPPSKPAFVHDTPEAGPSVQSLRSRTSSLSSTSSSVSRKGKERARVPNGDDLDSELSETESGDENSEEEEEEDDDEEKEGSQSSERSGHESENKDGPSTKEKSIEDDEEQIEDDDEEDSEESSDEEEEEPALKYSRLKGRIPEILAKDSASTISVSPRSVALGTHNGMVHILSYEGVKINSFRPHAASVTCLRMDESDDFVATSSVEGRVVIHSLSTPESYAFDYKRPMRAVALEPDFAKKKSRAFVCGGMAGNLILQEKGWMGYKEQILHSGEGPIWAIEWRRNLIAWANDLGVKIYDTNTGQRIGYIDRGASAPRAELFKCTLQWKDDQTLLIGWADHIKSVRVRSRPSSQASGNLPPLTVEMTAIYQVDCMISGIAPFGGSYVILAYIAPDRYENEATDDPIEQRRKAANRPELRIIDKGEETNADALSLANYHMYGCNDYSLVKSQKPGEEAFLVISPADVIVVRPRDEADHIEWLVEKERFQEALEAAEEMQKKHGSALDMKGIGLKYMRHLVSKEQFEQAAELAPKILEQDVAAWEKWIDIFVQHQQLPVIIPYIPTQKPRLGRRVYEMVFTHLLINDKQALLKVITSWPTEIYDLTTLVDAIQGELQASHDDPVLLECLGELYLINRLPAKALPYFLRIRKPYVFDLIREHNLFTAVRDQALQLVTFDQERKKAQGKRENQRGEKTDDAEMGSVEGDKSKHGAAIQLLVDHVHSIPIERVVHQLETKPHYLYMYLDALLDKDPQYSLPYSDRMVELYAAYDVDRLMPFLRTSNFYDLEKAYAVCKERDYVPEMVFLLGRMGNNKRALMLLIERLGDVERAIEFAKEQADEDLWEDLLAYSESRPDFIRALLEHVGAEINPIRLISRIRNGMEIPGLKPALVKILQASNLQVSLLEGCQHILNGDCAGLMGQLQKGQTNGLKASFTSTCAVCSKPAFTNSPSLVLIYLCRHLVHAECVLPEGVDLPVRQENASVAYLLADEGRMGGRRGAAWKARNLGARLGYAAAVRVRVKQCPVCESKQGH
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MTESDERSLRDLLLESADDLENVLKMIIDTLINREKSVMLKSGESVTNIVRLFDAKQESVRKLLQKVPEFQERESLIRTLKAHVEKRDEVIQQVENNLKACEVALTRSCFHANQKVKKMNEAALRPVNSETLIKLSHQISKHNSVSAPLTWQIGDPSRPFPQEHEFRTGQLLNPKIQSSGPQILLGKSSAQKPIIASPSASSSNGGTAPTRTVGTPLVNSATNGDYSPRTGYGAEETSPIQEQVLLGVTPNEKQWQNPPMPGAATSSQSPLSGAPQSPSSPSVKLKISGIPNRPGDIDQVQEVRDVEQMSSDSSNSSDSSDDEGSSKKTRGRNK
The following text describes a protein:
Function:
Probable non-functional open reading frame (ORF) of V region of the variable domain of immunoglobulin light chains. Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Subcellular Localization:
Secreted. Cell membrane.
Sequence:
MALTPLLLLLLSHCTGSLSRPVLTQPPSLSASPGATARLPCTLSSDLSVGGKNMFWYQQKLGSSPRLFLYHYSDSDKQLGPGVPSRVSGSKETSSNTAFLLISGLQPEDEADYYCQVYESSAN
The following text describes a protein:
Function:
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type IV membrane protein.
Sequence:
MATSTGTGWAQLRQQARSLETQTESLFHTYAQYASMTKLPPKPSEEEQRIESQLKDLLEKREALISQLSRLLDSEATLTASALKQSNLARNREVLQDHRRELQRLNAAIAESRDRANLLSNVRSDIDAYRNSNPAAAEADYMLEERGRIDESHNMIDGVLSQAYAINESFGLQRETLASINRRIVGAANKVPGMNALIGKIGTKRRRDAIILGAFIGFCFLMVFFFR
The following text describes a protein:
Function:
May be involved in spermatogenesis.
Sequence:
MGNLQSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAARHWLPFQVLNSCPCKCYCHHQPRHRRLPRNVSAWLSTSTNHLGEPPWVATIKLSGSLVAKLEHYDLQATHSN
The following text describes a protein:
Function:
Peptide antibiotic inhibiting growth of Gram-positive bacteria in the dimethylated form plantazolicin A. The desmethyl form plantazolicin B has no antibiotic activity. The mode of action appears to be disruption of cell walls and lysis of cells. Inhibits B.subtilis strain HB0042, B.megaterium strain 7A1 and B.anthracis (MIC=2-4 ug/ml). Weakly inhibits Gram-positive bacteria B.brevis strain ATCC 8246, B.subtilis strain 168, B.cereus strain ATCC 14579 and strain CU1065, B.licheniformis strain ATCC 9789, M.luteus, B.sphaericus, P.granivorans and S.pyogenes (MIC=128 ug/ml). Does not inhibit B.pumilus, P.polymyxa, Arthrobacter sp., S.aureus, vancomycin-resistant E.faecalis, L.monocytogenes, methicillin-resistant S.aureus or Gram-negative bacteria E.coli strain K12, K.terrigena, Pseudomonas sp. and E.carotovora.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MTQIKVPTALIASVHGEGQHLFEPMAARCTCTTIISSSSTF
The following text describes a protein:
Function:
Component of the seco-iridoid and derivatives monoterpenoid indole alkaloids (MIAs, e.g. vinblastine and ajmalicine) biosynthesis pathway. Catalyzes the methylation of loganic acid (6S,7R) to produce loganin. Weak activity with secologanic acid as substrate. Inactive on deoxyloganic, dehydrologanic, epiloganic and loganetic acid.
Sequence:
MVATIDSIEMPALPTAVEAHPMKGGDDSHSYSQNSCYQKGVIDAAKAVIVEAVNEKLDLENNPIFDPIKPFRIADFGCSTGPNTFHAMQNIVESVETKYKSLQKTPEFHVFFNDHVNNDFNVLFRSLPPNREFFAAGVPGSFYTRVFPKNSIHFAHCSYALHWLSKVPKEIQDKNSLAYNKGRIHYTGTEKHVVKAYFGQFQRDFEGFLKARAQEIVVGGLMVIQIPGLPSGEVLFSRTGAGLLHFLLGTSLMELVNKGIINEESVDSFNLPQYHPSVEDLEMVIEMNDCFTIERVGTLPHPMKNLPFDVQRTSLQVRAIMECILTEHFGENILDPLFEIYTKNLQENFHVFDKEIRKDADLYLVLKRKGN
The following text describes a protein:
Function:
Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins. In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1. Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Required for survival of B-cell progenitors and normal antibody production.
Sequence:
MRCQNCCHLAAVGVLAFMLLDYVQSATKDYYAILGVDRSASQGEIKKAFRKLAILYHPDKNKEPDAEEKFMEIAKAYEVLSDEDKRKQYDRLGANAYENQGARGGGGGGGGGGGGGRPNFNFKEFYRGFDSSFHQRKSRESHKRGHKQKFGNFDFDFDSFWNDFDDDKMFANMGGFDGFGGFKDHGFGGFDSAFANGHFGNGHFSQKTSFQARHDARHEAGSSGRSCRTVTQRVGNTITTYTDCS
The following text describes a protein:
Function:
5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low.
Subcellular Localization:
Mitochondrion. Nucleus. Chromosome, telomere.
Sequence:
MYQRATHGLKRTNPAPTDPAKRPKLKQGTLSFLYDAKKKAAAVAAPARLPVGNAPERRLPAAAGLPALRSALFDSQGSFEEATDDAYITSMLHEKPVHNFKTLSRSSSVLAPAENGQRLASHGVRKPPSGTSAPAVDSPPPRRIAGVRSHNPVPESTAAREVPPFTVARRLKPVATHRVAPARSPSVSSAVVLSKEQEAVRDIIVHDRLNVFYTGSAGTGKSVLLRELIRTLRAKYGTVAVAVTASTGLAAVNIGGMTVNRFSGIGIGSGSLEALAARAKKKREVYERWKRTRVLIIDEVSMVDARFLDKLDYVARQLRGKPDAVFGGIQLVFTGDFFQLPPVTDRSAGNEGPLFCFESRAWQQGIQKTLCLSQVFRQQDTELVDLLNAIRFGEVTPQVAAQMRQFEREVVYGDGIEPTELFPTRREVEQANRRRLERLPGFGMTFEAYDSGNVGGRFSSYFDAVMAERTLALKEGAQVMMLKNKDDQLVNGSVGRVLFFTTAALWGRVEREHMHALEDPEFVLDMRLVCQAIGISESARSPELLQAIAARPALRRPHLQEFLSRAPHEPRDGLLPVVRFVVAGRARFELVQREEFPVEVPAGPHAAGDASRLQVPLVPCWALSIHKAQGQTIPRLKVDLRRTFEAGQAYVALSRAVSKDHLQIINFDPKKIKADPKVKQFYHTLELLPTA
The following text describes a protein:
Function:
Catalyzes CTP-mediated phosphorylation of dolichol, the terminal step in de novo dolichyl monophosphate (Dol-P) biosynthesis. Dol-P is a lipid carrier essential for the synthesis of N-linked and O-linked oligosaccharides and for GPI anchors.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MVAIIPHASFTTIKLTQKTEGSQMPTEEICKINMRTRKFDVGGNSRDFECFYSNFVQTVILLGTFFYCVERLQPWSIVTADISYKQIFVNVFVVCLIMVGLIFTKYWQHGYKSLPKFDTIYSLYLPFMVSLLFDTSSTVINTILILSVLNSYRWRTQLVVIILQLCLIFFNFEAGDRLKNIISIVINSLLSLILKYIGQLKSLDNIDSNLFSILLTNILYVSEAGTVHFRILKGIILALTTIISINYVLKKVMHFKPFMLSISFAIGLPLFANTFIHLEDGENPLLWLVKYILESTIRQKILFAWSSILILSIPSILIEKDSLSLNTSRKLWHFIIFLLIIPSFQMDSNFVKIALSGTIPVFLSIEYIRFQNLPPLGSAIELQLRRFADDRDHSGPLIISYLYLLFGISTPLLMNNSPMGLIGLGIGDSLASIIGKRYGRIRWKGTQKTLEGTLAFIVTSFIVCLVLLRFDKAAIFNHLTTLQLLTLCTLSGVLEGNSVLNDNILIPAFMMICEKLITL
The following text describes a protein:
Function:
During the asexual blood stage, initiates the proteolytic maturation of several rhoptry proteins and thus, is required for merozoite invasion of host erythrocytes and probably the subsequent development of the ring-stage. Cleaves rhoptry associated protein 1 RAP1 and apical sushi protein ASP during schizont maturation. Also cleaves rhoptry protein RON3.
Subcellular Localization:
Membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, rhoptry. Note=In schizonts, localizes to the bulb of rhoptries.
Sequence:
MFFINFKKIKKKQFPIYLTQHRIITVFLIFIYFINLKDCFHINNSRILSDVDKHRGLYYNIPKCNVCHKCSICTHENGEAQNVIPMVAIPSKRKHIQDINKEREENKYPLHIFEEKDIYNNKDNVVKKEDIYKLRKKKKQKKNCLNFLEKDTMFLSPSHDKETFHINHMNKIKDEKYKQEYEEEKEIYDNTNTSQEKNETNNEQNLNINLINNDKVTLPLQQLEDSQYVGYIQIGTPPQTIRPIFDTGSTNIWIVSTKCKDETCLKVHRYNHKLSSSFKYYEPHTNLDIMFGTGIIQGVIGVETFKIGPFEIKNQSFGLVKREKASDNKSNVFERINFEGIVGLAFPEMLSTGKSTLYENLMSSYKLQHNEFSIYIGKDSKYSALIFGGVDKNFFEGDIYMFPVVKEYYWEIHFDGLYIDHQKFCCGVNSIVYDLKKKDQENNKLFFTRKYFRKNKFKTHLRKYLLKKIKHQKKQKHSNHKKKKLNKKKNYLIFDSGTSFNSVPKDEIEYFFRVVPSKKCDDSNIDQVVSSYPNLTYVINKMPFTLTPSQYLVRKNDMCKPAFMEIEVSSEYGHAYILGNATFMRYYYTVYRRGNNNNSSYVGIAKAVHTEENEKYLSSLHNKINNL
The following text describes a protein:
Function:
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Also involved in MHC class I antigen presentation in cross-presenting dendritic cells by mediating cleavage and maturation of Perforin-2 (MPEG1), thereby promoting antigen translocation in the cytosol. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation.
Subcellular Localization:
Lysosome.
Sequence:
MVWKVAVFLRVALGTGAVPIDDPEDGRKHWVVIVAGSNGWYNYRHQAAACHAYQIIYRNGIPDEHIIVMMYDDTAHSEDNPTPGIVINRPNGMDDVTPQNFLAVLTGDAEAVKGIGTGKVLKSGPQDHVYLHVKYLNETIHYMYIHKMYQKMVFYIEACESGSMMNHLPGDTNVYATTTANPRESSYTCYYDEKRSTYLGDWYSVNWMEDSDVEDLTNQTLHKQYHLVKSHTNTMMQFQSMKHKASSPISLPPVTPLDLTPSPEVPLMIVKRKLMNTNDLEDSRQLTEEIQRHLDARHLIEKSVRKIASLLAASEAEAEQLLSERAPFTGHSCYLEALLHFQTHCFNWHSPTCEYALRHLYVLANLCEKPYPLHRIKLSMDHVCVGRY
The following text describes a protein:
Function:
Involved in the uptake of non-siderophore and siderophore sources of iron. Has a role in the retention of iron in the cell wall and periplasmic space.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Sequence:
MKFSTIFGATTVMTAVSAAAVSSVMTTKTITATNGNNVYTKVVTDTADPIISYSTTRTVVVSNSDATYTKVVTEGPDTTSEKSTTKTLTLTNGSGSSTNLYTKTVTQAVESSTSSSSSSSSSSSSASSSGAAPAAFQGASVGALALGLISYLL
The following text describes a protein:
Function:
Heme-binding protein which promotes neuronal but not astrocyte differentiation.
Sequence:
MDREAATSEERRPAAGSMLRLGRRGLLLGLAAAAAAVMAARLMGWWSPRAGLRLFIPEELARYRGGPGDPGLYLALLGRVYDVSSGRRHYEPGAHYSGFAGRDASRAFVTGDYSAAGLVDDVSDLSFSEMLTLQNWLSFYEKNYEFVGRVIGRFYGEDGLPTPELTRVEAMITKGLEARQEELKEKQKFPPCNAEWSSAKGSRLWCSPNSGGVSRDWIGVPRKLYRPGAKEPHCVCVRTTGPPSDQTMDNPIHRNRGDLDHPNLGEYTGCPPLAITCSFPL
The following text describes a protein:
Function:
May be involved in the facilitation of anaphase progression in mitosis.
Subcellular Localization:
Nucleus.
Sequence:
MVLSKRPVRISKACENCRKRKVKCSGGDVCFECQKYNENCVYRQFYRKIKRLKYNNDNSKIDNFSNEQMNIPEFISVRNLNDDSSSIEFFGPASNISFVNQLNHYLRKAERNGYDFLSEGQNDITPEEERKGLEKFGMKLMVLKDNANNFDFSLSNITTEKMNGLLIAYLETWHIPCPIFKAEDLFNLSVRTWKNPSASVHDKALLYLILSIGSAASYFDLQSNSSTLPLARGFFNLALRTVPHIFTELSLDAIRIVFFMSVSAGNLGDTALSYLYSGTAVRMSLAIGLHKCKNFSNDLSDKYQNIRLWVSVWQWEGYWSFCVGRPSCSRQDIPIPAVPNEAFSFSGYGEHGRFLINHEHMRLRVFFSSCCSKIQSEIYSTNRNLLSVLQTVEQISKEVDKEYFSSTNHQLIRSEIGEYCKTLDINSCREWFWIRIYYLYLKLMIFRPFLIFLAYVNISKTSAPDDIIEGLKRGSDQCVQEAIDISKFIVQLNRKVRMLQPIFFICTYLESACTVLLFYIASNSAKIQGQLATEIWAVLRDTCSFLQGSSGPYVGSVSTIAKDALESLNNILVSKKYQDNSVNNTYFDKVMQHVLVHSPAFDDSSDPKFETNRSETPTQYTLDDSANDELMIPDLQGFWEQTLDWINN
The following text describes a protein:
Function:
Catalyzes the conversion of trans-anhydromevalonate 5-phosphate (tAHMP) into isopentenyl phosphate. Involved in the archaeal mevalonate (MVA) pathway, which provides fundamental precursors for isoprenoid biosynthesis, such as isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).
Sequence:
MTYRDFIDQLRENGKLVEVPQPVSPRFEASRIAKKTKAPVLFHDISGSKVIMNLLGSRDELASMLGVPKEEIIRKLSEVSPEGEVRIVSESPTLEVIENEVDLTRLPILTHYEKDGAPYITAGIVVSEYGGVMNASIHRLMLAGKDKLAARLVPPRHTYLLHKKAVEKGEPLPVAIVIGCDPTITYATTTRVPVGKEFEYAAALRGAPVELFECSNGVKVPHSEIVLEGYVDPVEKVDEGPFVDITGTYDMVRKEPVIRITRVLHRKDPIYHGILPAGPEHLLMMGVPYEPRIYRAVGEVTTVKNVVLTEGGCCYLHAVVQIKKQTEGDAKNAIMAAFAAHTSLKHVVIVDEDINIFDPADVEFAVATRVKGDMDILIIPNVRGSSLDPRGAPDGTTTKVGIDATKVLIEKENFERAVIPEE
The following text describes a protein:
Function:
Phosphoglycerate mutase-like protein lacking PGM activity, but having a low metal-independent phosphoserine phosphatase activity in vitro. May be involved in serine biosynthesis.
Sequence:
MGHEWIDAEREFKWSEDVKVESEVTEIVLVRHGETTWNAAGRIQGQIESDLNEVGLKQAVAIAERLGKEERPVAVYSSDLKRAKDTALMIAKTCFCPEVIEVPDLKERHVGSLQGLYWKEGAEKEPEAYSAFFSSQNDLEIPGGGESFDQLADRSMDALEQIAKKHKGERVIVVTHGGVLRAIYLRITQASSAGKLLNASVNVVHLRDQKWIIDSWSDVSHLSSVGFLQRGFDGDAKP
The following text describes a protein:
Function:
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subcellular Localization:
Mitochondrion.
Sequence:
MIINNLNKLNKFNSFQRYYSLQTSVKLNDTSNSNNSNGNKNNIKYIVKNNNDYLKSNKTGDLWELIVGIEVHAQTKTKEKLFSNSLNIGSMEGFKANSRVSYVDAAFPGSLPVLNEKCVEQAIKTGLAIGGKINKYSYFDRKHYFYQDLPQGYQITQLNAPIVQGGQLILDLKDNRKHKINISHIQLEQDSGKSIHDLHPTKSLVDLNRAGIGLMEIVSQPDFTSSEQVGLYITQLQHLLKHIGSSDANMQFGELRCDVNISVHKPDTPLGTRVEIKNMISAKAIVSSIDAEAARQIEILENGDIIKRETRGFNQDSGETFHLRTKEDEVDYRFFPDPDLPPLITSEETIERLKNQIGELPQEMRDRLIKQYDISLYDANILVNDHKAAKFFEQCISFGGTKRDPKKLLTWILRDIYKWSNSNNVTDFSTININVETLTQIYDLVESGYVSMNPAKEILEMILNGDKRSPKEIVDHLGVSQISDHQLLEELCRKLVDAHPNEVKDYHEGKIRLFKFFVGQIMKETKGRSNPEIVNNYIKKYLDLKKDN
The following text describes a protein:
Function:
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein.
Sequence:
MEISEILPFIAGIASFLVAGGLVAWISKQPAGTKEMMDISNAVKVGAAAFLKREMKIIIPVAIALTVIIGAFLTPSNGLAFAVGAALSAVAGIISLKITVKAAVRAAHLSNDGLGKTFAMAFRGGATVGLAVPAMALMAIAGLYVIYPDPITIAGVGIGASLIALFIRIGGGIFTKAADMGADLVGKVEANIPEDDPRNPATIADNVGDNVGDAAGMGSDVYESYIVTILAALLIAALIGAPNYFLYPILVGSSGMIASIIGVVIVGSKGVTDVMKPLNRSFYVSAAIAIALNYVFITQFIEQNQAAYALFGTTVIGVILVPVIQKITDRYTSYQHGPVNEIADSAKWGYASLTLMGIIKGMQSTGPFMIALVVAIIISYSIAAAAAPEGADPVLYGIFGTSLTAMAMLSLAGIVLSIDAFGPIADNAGGIVEMTGMGEENRKVTDEIDAVGNTTKAVTKGFAIASAALAALAMIQAFQFEAAHIFEGVLDLDYSLTNPAIIVGLLVGGLIPFIITGQLINGVSRAAGKMVDEVRRQFKSDPEILTGKSKPDYAKCVDIATVASIRELWKPAIVAIIAPIILGIILGPTAVAGLLMGSVVTGILLAYHLANTGGAWDNAKKLVEMKGEKGSEVHKVAVVGDIIGDPYKDTAGPALNTVIKLLNTIAIVFVSAFVAILAI
The following text describes a protein:
Function:
Involved in the guiding of mitochondrial tubules to the bud tip during cell division.
Miscellaneous:
MISCELLANEOUS: Present with 1070 molecules/cell in log phase SD medium.
Subcellular Localization:
Bud tip. Bud neck. Mitochondrion outer membrane; Peripheral membrane protein.
Sequence:
MNSPTMKSEQLTPKLSPMSFCLDDQRNAGSFQNLLNSPTKLKLDTGPIGNSLLYPTSLSKLSELSRGGRSKQRRGSDTMRSVSPIRFQFLNNTPKMLKPEYLSQTTSNLPLLSALLKNSKKTTSEGQNSNPDPLNIEKNIIKQSIKDKLEQLRSSESVAQVQKKERNPPSFEAKVCAEEPILRKNAEGLLPSYVPVPATPLEDPENHGVRKVEDKGLRVVSGGSTQCLSTEVNELPKDLNLDNLPTDNNGFVQYGLKGNNNNNRYSFISSTSTDYEPEWCDGQQHISMQMASMANAEEANSREKSNLDIKIKQLELEITELKLQNEKLVHSMTTNRYIEERFMLEVMKDPSIQAQRSQRDIERKVKQLEKKFFNCKKVLKKLTESSAVVATSTSKTEGNSARIPCPKTRLARVSVLDLKKIEEQPDSSSGTSSEEDHLTNDDTDANTSEDLNVAFEEEPTSAISTTASVQSGESKRGFQLNLPVQVEKKEK
The following text describes a protein:
Function:
Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).
Sequence:
MMQRNARSIPPAESAACCSSGPSQGDDSVSGPQYHSDDQVEVQSPYTEEIAFRPSNHAGSPSQPWPISLQDNMGPVREIVCIEPNVATMAANTPSGRASLQIQDDIQINDPIRAMTPTLMPATTRPRMAADNPSSMTPAMMPVPTLPWMAGENPRAWIPLLNLDYAPTPDVMMQGGSPGHCVSIGLHNDMRIESPIPNAIHTPPRSVSTPSPVRDLSRPVQRMVLPSGSPHSPAWAMAPSCATYHATENALREKASPQMQALEELEFMKRFMICAYLRQKRIEDELSVDYIRSLKHLSIVQFESEIWRAFGCKYIKFSDRVKNLDSDPGATRVYHCIVEITGDSVVKVFKGPYVQNTRTHLQKNVGDDNVLLVKFMGPSSESVIDFLPYHKVAEDGIILGLRRYRFFVYKDGGKDEKKKEEKINWENKNCASGVKCYFVRTESGWNMDEPYILSGKTINQARKLFMHIHTAPTLAKYMARFALILSKTITMEVDLSALHVIQLDDKPCSAENGGIVQRDGELLIHTDGTGLISEDLAEKCPTIMYKGKLLKSQDVQACDDTLTTSPRAKKQRLIASKPPLLIQFRMFYKGSAVKGTALIDRRLPPGTILIRPSMIKIKSDPKLCGVQSVNSWELIKMKADPKSYCVQSVNSLEIVTTSTKPKRTLTSKLLIALLRYGGVKEEFFMELLENAIEGAENARCDYEDALNIAFIYADMEDSISARMILSGIPLEDAYLQSRLAIMAQQERKGIKQGKLPISDCFYLMGTTDSTGKLKANEVCVILDNGPYCGNVLVYKHPGLHFGDIHVLTSRYIEDIHDVVGYSRYAILFPTSGPRSLADEMANSDFDGDMYWVSINEQLLKQFKPSKPWEWGQVNKPIQAEKKCLLDLDEPLLDRSLFHEFLKARFARSNALGTAADSWLVYMDRLLTDGVDEDESNVLEKKIKKLVDLYYLALDAPKARSKINVPAELTAKKYPHYMDRKESYHSTSILGKIYDEAEKKQSEKVEPVEISLDPRFTERAASSGYKYLNLWTGRYHGESSIFRIQGRNRPEVQRTLPKVQIHALRCR
The following text describes a protein:
Function:
TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.
Subcellular Localization:
Nucleus.
Sequence:
ETVQSFQFSLTSSSFTKPRSPRLGNSDHSTAQRSDSDSDSGTCSSHLRSSISFHMLLRIIQPQINKDKSVQVRGLALRLEKHEISRDVFLHSLRSIVGEHLLNSALYKELVDLTNEKHNKAEISSAQTLFPSSSAQIRQGYEAPDSKSLMHSLTSSIEPETSSKAIPKKTSVGKKKTSVGKKKSTKERVVSSPPSSKKQKLSCGAFPSIKELNDVTALSGIDIREEEEHLFSSPKKGSRVSETSLLIVQEEENMILHKIPLQKKLMETIAKRGLTKISNDVERCLSLCVEERMRGLIYNLIKVSKKRMDTEKTSQRTVITSDVKQQIMSINRKADEEQERKEAETQTSEKLNLPEGTTGVDGDKKRESCARLAKKQYDNQAANMAVRAATGTTDMMSRWQSMIEAKQKQQGIDKSGKDVINISNQDGSEVSGTPALDRKIGQIEVMVPQVRRCSITVKDVIAVLERDPQLSKSTLIYKLYLFYT
The following text describes a protein:
Function:
Cyclic nucleotide-regulated potassium channel activated by cAMP.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFKPLISALAQFVAATAGRNMTKAAYVAVGVGLLSMVLLTVGPAYETAPRWVDALLWACLAYFVFEWVVRLRHMRRTERLALYMSSSAGIVDAIGALAVPVALVLGVELRTAWLLSVLWVLKVVPGIPGLRQLRRVLVLESGPLVSVLVIFLMVVFLASVAEYFLERDVQPQTFGSVPAALWWAVVTLTTTGYGDVVPVTPLGRMVAALVMISGLGVFGLWTGILATGFAAETRRDNFLKTWESVSKVPFFAALGPAAIADVTHMLRTMELPARTMIIRKGTQGDCMYFIAAGAVEVDLPGKKVQLGEGAFFGEMALLGNNMRGANVSTTKVSRLLVLDLVDFRVLMARHPDLAETIDAEAKRRTLENR
The following text describes a protein:
Function:
Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidic acid (PA) between membranes. Binds PA derived from the phospholipase D signaling pathway and among the cellular PA species, preferably binds to the C16:0/16:1 and C16:1/18:1 PA species.
Sequence:
MLLKEYRICMPLTVDEYKIGQLYMISKHSHEQSDRGEGVEVVQNEPFEDPHHGNGQFTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDSIFDSEAKDLEREVCFIDIACDEIPERYYKESEDPKHFKSEKTGRGQLREGWRDNHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGVFPPAISISGIALLPSSVRSAPSSAPSTPLSTDAPEFLSIPKDRPRKKSAPETLTLPDPEKKATLNLPGVYASEKPCRPKSE