lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (By similarity). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Domain:
Contains eight transmembrane regions plus two helical hairpins that dip into the membrane. These helical hairpin structures play an important role in the transport process. The first enters the membrane from the cytoplasmic side, the second one from the extracellular side. During the transport cycle, the regions involved in amino acid transport, and especially the helical hairpins, move vertically by about 15-18 Angstroms, alternating between exposure to the aqueous phase and reinsertion in the lipid bilayer. In contrast, the regions involved in trimerization do not move.
Sequence:
MTKSNGEEARLGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQPNETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLISQESEIEKSMDSETKM
The following text describes a protein:
Function:
Voltage-dependent high-conductance channel with a slight cation-selectivity; selective for amino acids but excludes triosephosphates or uncharged sugars. Non-essential amino acid-selective channel protein and translocation pore for NADPH:protochlorophyllide oxidoreductase A (PORA) and possibly PORB (By similarity).
Subcellular Localization:
Plastid, chloroplast outer membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MDPAEMRYLEEEDGPLMKTIKGSITGFGAGTIYGTILATWKDVPRVERNVALPGLIRTLKMMGTHGLTFAAIGGVYIGVEQLVQNFRSKRDFYNGAIGGFVAGASVLGYRARSIPTAIAAGATLAVTSALIDSGGQTTRVDNGREYYPYTVEKRAEADS
The following text describes a protein:
Function:
Facilitates lipid transfer from the outer to the inner plastid envelope by bridging TGD4 with the TGD1,2,3 transport complex. Required for endoplasmic reticulum-to-plastid lipid trafficking as part of the eukaryotic pathway of thylakoid lipid assembly.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein. Note=Is resistant to both thermolysin and trypsin like an inner envelope-localized protein, but physically interacts with the outer envelope protein TGD4.
Sequence:
MVLSDFTGVGVGFGFGVGCGFGVGWGFGGMPMNILGVGAGGGCGVGLGLGWGFGTAFGSHYRSSRLTFQGIELETADKREEVVANMSKNST
The following text describes a protein:
Function:
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSIDLDNPQENIKATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQVWPRMAQLSRKERLRRETALSAESRWAALLPFPQELAEKSTEDPAAAAEAADAIILDDELIQWKRKRLAASSLDVSYRSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRLGDLNYLIYVFPDRPKDEVYSKYYTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGGGSATYMDQAPSPAVCPQAHYNMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQWIPHAQS
The following text describes a protein:
Function:
Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell projection, growth cone.
Sequence:
MKCWRIPVIITVLQQTWILAMEIPPDVRQPPMIYKESVQDYIVDPVDPIIVECEATGNPPPVFTWTRNGVYLNVARDPQVSMRWRSGTLEIFFWGRPDDYEGIYQCTATNEFGTALSSYINLRVSKARTWLKEYLEPVTVVVGLPLILPCNPPEGPPKPDTYWLNSTMSPIRQDRRVSKSENGDLYFSSIVADDALTNYVCVARFPFTNTIQQKPPLILQVLTARMAAHTAPKFLKPKGTASTRIAMLGEELILECFAAGVPTPSIKWTKDYEEMTMTGKKLENFNKTLRIKKIAMDDGGDYICTASNRMGSLDHIITVRVKSVPFWLEKPESLVLSRDDGGSMVCRADGIPRPQIQWLVNGEPISDAPRSPGRQVSGDTLTFRGVVPDSAAVFQCNASNPYGYIMTNAFLAVMDMKPRLLGPRDELFKTTEGNLTLLDCPYFGSPKPVLRWSKGGVGTLEGGRYRTLPNGTLEIRNTKLQDQGAYVCVASNVIGRDEKEVQLEVKEPIKIIRAPHNTVVIRGSLARFDCKIKFDTSLDVTVTWLKDKKFLILGRRMTKDEESLSIADVYRRDEGVYTCRVKSELEEVTTSAKLTVMDRPDPPTDLEISDPSERSVRLTWTPGLSNHSPIKEYLIQYTENLLADYWLLPSGWKNLTSYPGSLNSVILQLTPFVEYTFRVIAVNGIGPSKPSWASEYYQTGGAVPDAIPRNIQGLGYGVFRNNMEISWEPLEYREWNGPKLGYMVWWRRRDSREEWKNYTTYWWCSTIIYDTDTFTPYEIKVQAINFFGYGPESPVVIGYSGEDRPVAAPSELSVSDIESTTLTVHWEPVARADIMGEIKEYKVYYWRESSRLPWHVVTRRIKTKSFKANGPRLSGTLTGLVPFSNYKMYIVVANNRYEGPPSHNIEFQTPEGVPTIPRSFRIMHRHYDTLYLDWEEPAEPNGVLTGYILKYQSLNVSVGIQVENIPPNITYFSLRRLDRYTRYKFSLAAQTEVGVGEAFTEESPHFTTEEYTRDQVDIVTQGWFIGLMCAVALLVLIMLIVFFIKRSRGGKYPVRDNKDFALEPMDENGTFDYRSLERITRVSTIPYSRREEESRQGRSQGAIEHINRRTNSDDSLMEYGEGEEMEFNEDGSFIGEYTGVSKRNMDRSPYHDSSEPTSPVAIYSFA
The following text describes a protein:
Function:
Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: Appears to be the dominant isoform in peripheral blood cell fractions. Contains a transmembrane helix.
Subcellular Localization:
[Isoform 1]: Nucleus. Note=Coexpression with BCL10 induced translocation from nucleus to cytosol; [Isoform 2]: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MTDQTYCDRLVQDTPFLTGHGRLSEQQVDRIILQLNRYYPQILTNKEAEKFRNPKASLRVRLCDLLSHLQRSGERDCQEFYRALYIHAQPLHSRLPSRHALRKFHITNHACLVLARGGHPSLPLMAWMSSMTTQVCCSPGLASPLASAPPQRPPSGPEGRVWQAQAVQMLVSVSHFLPLPPSLSHGSFHTAWGILYVHSCPSFSNLIPRGSLHVCVDSNLVPTAAWRS
The following text describes a protein:
Function:
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
Sequence:
MKYDLIIIGSGSVGAAAGYYATRAGLKVLMTDAHMPPHQQGSHHGDTRLIRHAYGEGEKYVPLVLRAQTLWDELSTHNEEPIFVRSGVVNLGPADSAFLANVARSAQQWQLNVERLDATALMTRWPEIRVPDNYIGLFEADSGFLRSELAITTWLRLAREAGCAQLFNSPVSHIHHDDNGVTIETSEGCYHASKALISAGTWVKALVPELPVQPVRKVFAWFKADGRYSTKNRFPAFTGEMPNGDQYYGFPAENDELKIGKHNGGQLIQAPEERKPFAAVASDGAEAFPFLRNVLPGIGGCLHGAACTYDNSPDEDFIIDTLPGHENTLVITGLSGHGFKFAPVLGEIAADFALGKTPSFDLTPFRLSRFSQ
The following text describes a protein:
Function:
Probable secreted lin-12/Notch ligand or co-ligand involved in the mediation of Notch signaling. Involved in the lin-12/Notch pathway signaling of cell fate in vulval precursor cells (VPCs), acting redundantly with dsl-1 and lag-2. Required for normal octanol avoidance response, acting via both lin-12/Notch and glp-1/Notch signaling pathways in neurons, in concert with lag-2. Involved in regulation of sleep-like quiescence during the larval to adult transition, acting via Notch receptor activation and in parallel with EGF signaling.
Subcellular Localization:
Apical cell membrane; Peripheral membrane protein. Note=Concentrated on the apical surface of vulval precursor cells.
Sequence:
MNFITVAALAIVMVLAQANPARVRRNEEMSERYCIKHLDHYNKYCGDNAGPIDRALFGKVAKFCPAYEKHCAVGKAGLVELPDLGSPLVMPPVLPRGSDFASLDLPIADERKPAHIHSSRTAPQTTRLTAAIVATCTPECTAAHCTDECKCAHTHPKVHQMCNPPSSAAMAETCQRWYSKCTMFTPVQY
The following text describes a protein:
Function:
Modulates intracellular Mg(2+) levels to maintain cellular integrity upon Mg(2+) limitation. Acts by binding and stabilizing the Mg(2+) transporter MgtA, thereby leading to increased intracellular level of Mg(2+). May inhibit FtsH proteolysis of MgtA.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MLGNMNVFMAVLGIILFSGFLAAYFSHKWDD
The following text describes a protein:
Function:
Amino acid transporter that moves lysine into the vacuole. May also contribute to low affinity arginine import into the vacuole. Has also been suggested to mediate export of cationic amino acids from the vacuole. May function as an amino acid/proton antiporter.
Miscellaneous:
MISCELLANEOUS: Present with 1800 molecules/cell in log phase SD medium.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MQLVPLELNRSTLSGISGSISISCWIIVFVPQIYENFYRKSSDGLSLLFVVLWLAGDVFNLMGAVMQHLLSTMIILAAYYTVADIILLGQCLWYDNEEKPAVDPIHLSPANPINENVLHDVFNEQQPLLNSQGQPNRIDEEMAAPSSDGNAGDDNLREVNSRNLIKDIFIVSGVVFVGFISWYVTYCVNYTQPPPVEDPSLPVPELQINWMAQIFGYLSALLYLGSRIPQILLNFKRKSCEGISFLFFLFACLGNTTFIFSVIVISLDWKYLIMNASWLVGSIGTLFMDFVIFSQFFIYKRNKKFILN
The following text describes a protein:
Function:
PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4-hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens.
Sequence:
MSKSNLVISCLLLVAISNSLVRAQDLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQADGKKFDSSFDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGDQGAGNVIPPKATLLFDVELINIGNAPPTTNVFKEIDDNADKQLSREEVSEYLKKQMTAVEGQDSEELKNMLAENDKLVEEIFQHEDKDKNGFISHDEFSGPKHDEL
The following text describes a protein:
Function:
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
Subcellular Localization:
Nucleus.
Sequence:
MGITGLKGIVNTVCRKRTLKELKGIRVAIDGYAWLHRASASCSEELCENIPTNGLSSFCVKGALTLLNNEITPIFVFDGARLPSKITTENDRQQKRNENLKTARDTTISITERKKAYGQAVEILPWMASAVIQSLNEIGVESIVAPFEADPQLGYLCKIGYVDAIICEDSDLIVHGCKRILFKFNKFDETVEEFLSSDLDKTDFKGFTRNMLVYSCVLAGCDYCKNISKVGIKKAMKIIKSEPSISKALVKLIETHGTELDTMEKKIEYLTNVRNAIFTFNYAYVYNPVDQEVVNLNEVPEELNCMVDDLLGIKPNKQVAQEIANGTVDPDTHKPFEQFIDPNLFEKAMSLNTALTSYTSGSIKKFHQTEPSFNSYELDNLELFDVFEIIRNENNKTIRSRKSILQKYDSEEDFNENENAGIVIMKQPRKRSKNQPKPILSMTNLNFKPNLKTSFPLTDEELQTIKPKRKIENSYISSDFDLFIPSFDMYYMINQLK
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase involved in the degradation of non-functional 18S rRNAs in response to stalled ribosomes. Catalyzes monoubiquitination of RPS3/uS3 in response to stalled ribosomes, initiating a HEL2-dependent response that activates the degradation of non-functional 18S rRNAs.
Miscellaneous:
MISCELLANEOUS: Present with 922 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MVEPDMQKKASGGSGGSEMDTLNATSNSSKQGVSNNKRNPVSKKKPGNKVSDGRDNAHNYHGEGRRKSSKQQRSRTPYKETSTRINDQDIDLSIQEEILGGNFKLRGRKTQVSINHLLNFQLPEVEREKSRSSSSKKSNRRRDEHVHLHGDTFVNVNYRLLVDDRFDYPEQNCNPNVPVDQEKILRVIVPKGQNCSICLSEEPVAPRMVTCGHIFCLSCLLNFFSIEETVKNKETGYSKKKKYKECPLCGSIIGPKRVKPVLYEDDFDVTRLNQKPEPGATVHLQLMCKPHGSLLPLPVALHLDPLKCGNFPPANLGSIKHYAHIMKCGVSYSLELYQKDIVAIQEQYEIDKAIYNDSGKFVKQSIENINDQISTLLAATTDLSPLSNDINNGLDNFHFDDDLLTKYDDSSAYFFYQTLVASSTKYFLSPLDVKILLTIFHYYSKFPESIETTVENIHYDTVVTEQLIRRYKYIGHLPIGTEIALLDLDWRKIPFLPKEIYEQFAHELKQRRRKFTMKKQKEDKEKKLYEKRLEQEHAEFYRKENGNSLKFEDSVQMATHYESIVSSSIPLNSLGISMLGPPTNSCSTPQKQAPSHTKRTIWGTSIAVTEDEKASKENKEFQDMLLQRIRQEDSSDVTDSTDSPPTSNGKRGRKKKGKVMLFSSNHQALG
The following text describes a protein:
Function:
Regulatory protein, which plays a central role in chromosome stability. Probably acts by blocking the action of key proteins. During the mitosis, it blocks separase/cut1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of cut1.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The N-terminal destruction boxes (D-box 1 and D-box 2) act as a recognition signal for degradation via the ubiquitin-proteasome pathway.
Sequence:
MLPRTMFSYGKENAFPVTPISNRNGTKGAGSKRAPLGSTKQSNAPSSVTVPRTVLGGKSTNISKFISAPSTKKMSPMDISMDSPTILEPNSQGISRSAVQERSKRLSASPRRSSLTDTPLPNELEEDIEYMPPPVHLDPIQSLGFDDVAIDCETLDPWPSMQNKATSVTIRNTPASDFHVYKEFSDDDPIQFPLLSVDGDSPLTEKDTNLTTPATLKASDQQRKVLEKPSVSKQSSSRTRLSTVYRTKLASGKSIPRPLSHKLTRPRVTASGNSRRRPLSRSIHSLSSSRIDFSSLDTGLL
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
Subcellular Localization:
Cytoplasm. Mitochondrion matrix.
Sequence:
MRASPLVGCRGRPSAAASSGGATLAAAARAPTTRAPICGTLRCRDGRLSTAAVLTAGRRRAAPHRPSTARSLHVVARGAFGDGYGAGAGGRGGGGRRPRDLQQLMELLSGGGGEDPEQFLDLVSDAPRVMEPRRRGGAGPPLSMRQLAQAQAAQAEARRRAALQQQLLQLNMAAQAAARRQAEAEEEARREAARRAMLESARRHLPRYGTTDEVARLASALAAAGVRDPELCNAMVRQLVSEQQQQAQQAQQQWQAAWPPQPRQTAPQAQGQAPAQGQGQGRVAERDVDSNSLAELLDAFAAMRHRPSDAEMAELLRRHHLQQQAKQQQQQQAAAAAQAAAQQQALLQAQQQAAQAQAQRQQQAGRSQPMLQPRGMGIPKPPTPAPPPPPTPQQQQQQQQQQQQEEDAGPSTSGGVRTSPEAAARLLQSLSRMGYNPDDATLQRLLEQLQPQRLQLQPDAARAAQLQQQRQRQQQQVAAAAAAAAATEEQRRRQQAAQQQQQQQQQMQMQQQRQRQAEPERVAGAAPDEVEEEDDDNDEDELSFSLARDAQAVANAIRALERMGRRGEAAALRQRFQRHVQEVQERAARERAARLQQRRQQEQQQEAAAAARARAEAEAAQRQRAAAAAAAAAEAARREQESAAAAAEAAAERERERERQAAAQQQSLRGLLAKRLRAAGDWQQIRALLFTYAEAADFACVAAAAARLAELLAGPGGRRAAAGLGLRGRGELGDLLEGMAELALEPGAGRLAGASAEQAASLLVSVVALRYLDERLLVGLLRRLREVLHEAGPDSLAAALAALADCGVRPTPPWMEAVLARCGAQLAAFAPNDLAGLPVWLARLGAHPGRSWLSSYLDVLQAREGELSQAVVSEAVRAVAALDRPLLNAWREAAAARQQQQRQQQQAQGQQQGQQQQGERERDQAEPVQRAKQAQAADPDLQRANALASVDETLAEEAQDQEDGADQEEAEGGVEAAPGQPRAADASTSGRGAETATDTSRGQARGRGKVHAANASAPSSPPLQFIELDVDSEQQAPPRAAGAAAPTTTSSAPTAPAAVASSAATAGAGLGVGRGAGSEAAGGAAAGTQLPGSYSVDGFYTPLPYEGADEGEEEAETEEADSEQGEQRASGTAAATAATATADLEGSNLVLDEAVAEAVADAAHGGAAGTAAEAQQTAPTAKPGSGQGGIRIKVQSAKPEQPQQPQQKSQPQPQPQPPKAKPQPSPQEVAQARALRSLLLERYEAVAACAQQARERQERAARGEEASASDLGNGGGLGGGFSVPSGLGGGVSDRDVALAAKVLAARDQLARLQADFDNAKRRAELEREQATARAKADVLKPLLGMADNFERARQSIKPQTPGEAAVHDAYQALAGQLEAFLKQQGLEPVGGEGEVFDPNLHEAVMREDRDDVPDGTVTGVFQKGYRLGELLVRPALVKVAYS
The following text describes a protein:
Function:
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MSKKFVITWDNMQHYCRELAQRQMPAEQWKGILGVSRGGLVPAAILARELGIRYVDTVCISSYDHDHQRDMTVLKAPEHDGEGFLIIDDLVDSGDTARKIREMYPKAKFVTVCAKPAGKDLVDEYVVDIPQDTWIEQPWDMVLSYVEPVNRKQK
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MTSNIVFLPISRVREGYFPSVPSLLLCLTCSSSQIHLQSCNVVPLANQDCRQTSLASKEFQTGEDMIVASASTTHRCITKIYQLSNRSSSIFGSLLSILPKQCRNYSIVNIDARWCRSSAVSLGNVISYRQYQPKPAILMITQLYSTDSDNEKKQFRSALTESDSRAETQLSTARKVAKAGKDASYFGVILIGFGITGILFWSVFRELFSSNSANNIYSHTLKLVKSNQQVIDALGTPITAHGDQSGRNRYRNISSQEYIVDDVNYMRVRYYINGTRNKGTVHVDLKEVSRGNYDYRYILVELTGYQRGTIMVEDNR
The following text describes a protein:
Function:
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MDPRVEDIRRAIRSFKDFPKKGILFRDVLPIFHNPDVFRKLIDVLAEQVRSSVPDVSAVVGIEARGFIIAPALALALNVAFVPVRKPGKLPGTVKSQAYTLEYGEDKLEVQEDGFLKGRKVVIVDDLLATGVGLTCLGTTVFLKFNCDRPAQGRSARFYENSVECSSIKILRITRPPFTSRKGAAASEVI
The following text describes a protein:
Function:
Digests cleaved signal peptides in vitro, its in vivo function is unknown. This activity is necessary to maintain proper secretion of mature proteins across the membrane.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MRTLWRFIAGFFKWTWRVLNFVREMVLNLFFIFLVLVGVGIWMQIGNGSNSEQTARGALLLDISGVIVDKPSTNHRLGALGRQLFGASSDRLQENSLFDIVNAIRQAKDDRNITGIVLDLKNFTGADQPSMRYIGKALREFRDSGKPVFAVGENYSQGQYYLASFANKIWLSPQGQVDLHGFATNGLYYKTLLDKLKVSTHVFRVGTYKSAVEPFIRDDMSPAAREADSRWIGELWQNYLHTVSANRQISPQQLFPGAQAIIDGLTSVGGDTAKYALDHKLVDALASSADVEKALTKQFGWSKTENNYRAISYYDYSLKTPADTGGTIAVIFANGAIMDGEETPGNVGGDTTASQIRDARLDPKVKAIVLRVNSPGGSVNASEVIRAELAAARAAGKPVVVSMGGMAASGGYWISTPANYIVASPSTLTGSIGIFGVINTVENSLSSIGVHSDGVSTSPLADISMTKALSPEVQQMMQLSIEYGYKRFITLVADARKRTPEQIDKIAQGHVWTGEDAKANGLVDSLGDFDDAVAKAAELAKLKQWHLDYYQDEPTVLDMVMDSMTGSVRAMLPETIQAMLPAPLVSAANTVKAEGDKLAAFNDPQNRYAFCLTCANVR
The following text describes a protein:
Function:
Involved in the degradation of long-chain fatty acids.
Sequence:
MHKHIRKAAVLGSGVMGSGIAAHLANIGIPVLLLDIVPNDLTKEEEKKGLTKDSSEVRSRLSRQAMKKLLKQKPAPLTSAKNTSYITPGNLEDDAEKLKEADWIIEVVVENLEVKKKIFALVDEHRKTGSIVSSNTSGISVQEMAEGRSDDFKAHFLGTHFFNPARYLKLLEIIPIKETDPDILKFMTAFGENVLGKGVVTAKDTPNFIANRIGTYGLLVTVQEMLKGGYQVGEVDSITGPLIGRPKSATFRTLDVVGLDTFAHVARNVYDKADGDEKEVFRIPSFMNDMLEKGWIGSKAGQGFYKKEGKTIYELDPVTLTYGERTKMKSPALEAAKQAKGTKAKMKALIYSDDRAGRLLWNITSQTLLYSAELLGEIADDIHAIDQAMKWGFGWELGPFEMWDAIGLKQSAEKLEQLGADMPGWIKEMLDKGNETFYIKENGTVFYYDRGEYRAVKENKKRIHLQALKETKGVIAKNSGASLIDLGDDVALLEFHSKSNAIGLDIIQMIHKGLEETERNYKGLVIGNQGKNFCVGANLAMILMEVQDDNFLEVDFVIRRFQETMMKIKYSAKPVVAAPFGMTLGGGTEACLPAARIQAASEAYMGLVESGVGLIPGGGGNKELYINHLRRGHDPMNAAMKTFETIAMAKVSASAQEAREMNILKETDQISVNQDHLLYDAKQLAASLYDTGWRPPVKEKVKVPGETGYAALLLGAEQMKLSGYISEHDFKIAKKLAYVIAGGKVPFGTEVDEEYLLEIEREAFLSLSGEAKSQARMQHMLVKGKPLRN
The following text describes a protein:
Function:
Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Domain:
The selectivity filter, in which calcium ions are arranged in single file, is composed of two acidic rings separated by one helical turn along the central axis of the channel pore.
Sequence:
MATASLKCLKTLLNSCKCGDLRFQKYLLLKGSNLKCFGRYGFDVHKRSVQFLASNIGQDGNIDIKYEQGLVKFSVYLPSRRERCQFTLKATTNTLYNLIHDMKLEDKGIDRVVAYNLENERLARSTPLYLILQNDFYIYINDVKFHCKAPAIDALIKQHMSDVSNVKNAICHLYNALNVEQHQLAQEKSLQNKLEELHKEIYPMERMKTEIDMSANRRTRVLTWVGLGLMGIQFGFLARLTWFEYSWDIMEPVTYFVGYGTAIACYAYYLLTSQEYILPQVRDREFLFSVHRGAKARHLDLKKYNQLKEEIAQVDYDLRRLRDPLQLHLPLQYQKPLAV
The following text describes a protein:
Function:
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MVRCHVKSPTESPPGQQGSGQQGETEHPDQARELRPEDIPVYGRTHRGRYHYRHRSHTRRRPYRRRRRRACRHRRRRRGAAGPPCAPIPGTPQASRQGSGCRRMRRRRRRCRRQL
The following text describes a protein:
Function:
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
Sequence:
MPTPRKIETVSTLTEKLNRAQLVVVADYRGDGKGMSVADMTELRRKLREHGGEVVVAKNTLLKIAAHNTGHEALDPLLAGPTAVTLGYDDVSKVAKALLDYLKSGNKSFTVRGALLGNTLLPADALEQVTKLPSREQALAQVVGGIAAPVSGVVGVLNAAISNVLYVLQARIDQLQPQGETA
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as a non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHGVLGVKSYIPRSKELTDFEKRWKREFRDRNPKDDEMELDMFGIWWYDTVYGLAMALEKAGNDIDTTFRRKREPQTDLDAIGTSEMGSSLIPWIRNLTFKGLSGDFCIVNGQLQSSAYEVVNIIETRENHIGFWTRGNGISKKLNHRTNGLRAITWPGDSHVIPKGWEIPTNSKNVLKIGVPAKGLFVQFIDAKTDPETQQVIVTGFCVDVFNAVVSALPYAVKPEFIPFVTPDGKSPAGSYTDFLISNLSRFVVIVWVLVVLVLTSSYTASLTSMLTVEQLRPTHTDIDQIRRNGESVGYQKGSFVVGILKSIGFDDAKLKSYSTFEEYDRALQAGSRKGGVSAIMDELPYIRLFLAVYCNNYTMTNATYRTVGFGFAFPKRSPLLHDVSRAVLQVTEGKIMNISNQWFEEAASCDQQNRAKGNSSRLMLDSFKGLFLIAGLSSTAALLIFFSYFYIKTDIYWCHEIRLAESLLLWQKHLMCLRKMRLERQSQRQ
The following text describes a protein:
Function:
Mediates influx of magnesium ions. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MALKIRYQTTYEPFKVVDDIKEIPKDATIVWYDFDEPNEQENEWFKAHFNFNDLEVDDAINGMPRAKYKSYKDYQYLVFHSIMGSNYSPIALNIFIQDNVLVTYHHQTLESLNKVVYKYMNTLDAELDCADVVILILDMMVDKYFNFVYALEDSVYHFEDRHVDDRFNKMVMDSVFKLRSDLIKVKRVLFPMQELIDTMKQNGDLIIDNKHSLYIQHIDDHLIKQRNIIRTAQEMTNEIRENFESYTSFRMNSIMQVLTLVSVIFSPLTFIAGIYGMNFVNMPALHLHYGYYICLAVMFVIAVVLIIFFRRKKWF
The following text describes a protein:
Function:
Putative oxidoreductase that may contribute to the degradation of aromatic compounds.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEDAGLLLIRIMIGVVFLFYGTQKLFGWFGGYGIKGTGQWFESIGVKPGNVAAALSGLGELVSGILFILGVFLPLGAAIITIIMLGAIVKVHGAKGFANGAGGFEYNLVLIAVSIGVALIGSGAYALHF
The following text describes a protein:
Function:
Transcription factor that acts as a molecular switch in the NAC012/SND1-mediated transcriptional network regulating secondary wall biosynthesis. Is directly activated by NAC012/SND1 and its close homologs, including NAC043/NST1, NAC066/NST2, NAC101/VND6 and NAC030/VND7. Is required for functional expression of a number of secondary wall-associated transcription factors and secondary wall biosynthetic genes involved in cellulose, xylan and lignin synthesis. Functions redundantly with MYB46 in the transcriptional regulatory cascade leading to secondary wall formation in fibers and vessels. Transcription activator that binds to the DNA consensus sequence 5'-ACC[AT]A[AC][TC]-3', designated as the secondary wall MYB-responsive element (SMRE). Regulates directly numerous transcription factors and a number of genes involved in secondary wall biosynthesis that contain SMRE elements in their promoters.
Subcellular Localization:
Nucleus.
Sequence:
MMMRKPDITTIRDKGKPNHACGGNNNKPKLRKGLWSPDEDEKLIRYMLTNGQGCWSDIARNAGLLRCGKSCRLRWINYLRPDLKRGSFSPQEEDLIFHLHSILGNRWSQIATRLPGRTDNEIKNFWNSTLKKRLKNNSNNNTSSGSSPNNSNSNSLDPRDQHVDMGGNSTSLMDDYHHDENMMTVGNTMRMDSSSPFNVGPMVNSVGLNQLYDPLMISVPDNGYHQMGNTVNVFSVNGLGDYGNTILDPISKRVSVEGDDWFIPPSENTNVIACSTSNNLNLQALDPCFNSKNLCHSESFKVGNVLGIENGSWEIENPKIGDWDLDGLIDNNSSFPFLDFQVD
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MARFKLDVQKKQHRERSQPLQRKRLGLLEKHSDYVQRAKDYNSKKDRLQKLRLKASLKNQDEFYFKMINSKTVKGVHYNFNKANTPLDNQLVKLLKTQDFNYIKTCRAIEENKITKLKERLGSMIIRVQSEESGSSSDLKEQAIQLINQSITATHAKNTANSDQGGSDLDHDDHALVKPGKKTIFVDSVEEVKNFSITSLGKKTKKDKTQSASKSSSKKTKGKFTEEFSDAEDQLTPDPEKHMRKLMTEFQTRLTRLRVLQTAEREMELKKSLMGKGSKFLKFRSSTQKPKQDGLVNGRDLSWYDKLDRNQIIEDDLERERLEKLNSGIKTGAQVWKWKQERKK