lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MSYRMLLFLLLGTLPFFVYAMHIEPSSGEEAKRYLQQFGYLQKPLESDTEDFSSEEVQEALRIFQLSTHLPGTGVLDEDTIDKMRQPRCGVEDPFNQKTLRYLLLGRWRKKNLTYRIYNYTPDMSLAAARSAILAGFKYWSDVTPLTFKEVTRGRADIRISFHRRGNGCSRPFDGPGKVLAHADIPELGTVHFDEDELWTEGTYEGVNLRIIAAHELGHALGLGHSRFRSALMAPIYFGYKPNFRLHDDDVKGIQALYGKKDKIEEEEVVTTEEPAISAEPTPTSLTPDPCNDNLDAIILGPYGKTYAFKGDYVWTITDFGISPLIRIQSLWKGLPGNIDAAVHSPRTQRTYFFKGDKLWVYTNFKLNPGYPKLITRVPPNINAALYWEVNKKIFLFKGDGYWQWDELGWSNLSSKKISSLFTGIPSQLDAAVTWKNGKIYFFKGDKYWRVNKQLRVERGYPLSKAERWMQCYYFD
The following text describes a protein:
Function:
JanA and janB regulate somatic sex differentiation.
Sequence:
MNRLQLFSKGLRLIHKMSEEALAGVPLVHISPEGIFKYVLINVIDGGDASKAVVRGFDDCTWHADIFDREEEVFKKLGLRAECPGGGRIEHNPEKKYLKVYGYSQGFGKADHAQTKRILATKYPDYTIETSDEGY
The following text describes a protein:
Function:
Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.
Subcellular Localization:
Nucleus.
Sequence:
MSGKRLSDDLDPDYQDVVQPNKRLRSMQQDAKDATVRKIVTIIKDQFSQEIRNKEREIEVIDERIHQARGMLDRLRACIIASYYGGVGQKPNEPPDPNAANHPAIKKLIDRPKPAASANQAEESESSNQSAEASQEEKQPEEHDAGLPSLEEICDSVNKPDPAPAPPTQEPTSGSGFDFDRVLGRKVAGGPSRFCVKKRIIVGNVSKYITADKREENDQSTHKWMVYVRGPREAPRIDHFVKKVWFYLHPSYRPNDLVEISEPPFHLTRRGWGEFPVRVQLHFVDPRHKKVDIIHQLKLDRTYTGLQTLGAETLVDVELDRHLFDETGTPLYPDLSVLSSGLPAKAGAPPSSTGEELQASPVKHSTSTTAPSGGPCAELQATSSRVKASASAAKPSSSSSTELQATVKPSTSGAAPSSGSPTEVQATTSTAKASSSTASPPSSSGAEVQAAKPGTEKAEQESKPGASLVRRSPRAKSRQDTRKPSSPPEEISAKKPCKTSEADSLSKERVKPEETKHTNLKEEVEEKVLADAKTSKQKPVVMTTAIPSSSGTNVDSSKLKPVTMVTGGTVPISAVTIATSRAVSKTTAGSPKTFLGDQKEAPTLVVPVKVKAEPLSPPRVTPATVPTAREPVTFSRGVDTKGLVLPAQSKPLVGTAKPVKPGAVVGTVKPGATGGTVKPGAAGAPGVAAGTVKPGAAGAAGTAGGTTMVGTPPQGIVITKIVPTTSKPVTTVQQTLTLKPQGLTSKGVSTATQQNITIIKQVKQEAGMGVTMATQPSVVVTAGTGPKAVLTSPQKGTILKLSGLPGQSSSPVVGSGSHMIVGQSSAATVVSGSHMIVGQSSTSVVGSGSHMIVGQSSASAIGSGSHMIVGQSSASAIGSGSHMIVMSSQPSSSSTAQAVPRVVTSPPQGKAVLLSGVTPQMAQVPVKVEKMADGKVPVTPTKVGSASPTVPPGTPPQVRTISGAVIGGLSPVSKPHSGVAAGSIVQVAPQQLVTSPSVPGGSALVPPNVMNLPLVNVAPGAKVFLAAKSTDPAMKGKVILIPQTAIVKGIPLQQGQGSGVTVLQGSPVVQGVNMPAQVMGGTPQGGNIVHLVQGGGLASQGAGPTPTLTPQVTGQSQVRGERSSPGVAQTVKAGSTITLPLQPGTSYILMQQPQGGASASGNVPGSSPSRPTTLMVQQVPQEQPGKQQVQVVPQAQAAAQPGTKPMQSFRIIPSPQTGGQSPTTEPGAKAAPSVATAGGHTFIALTPQQLSQIGKPGSQQIGAGQTLLVPVQNMQMAAAGAPTAQLVTKSASTPTVLTPSPSHKGATPRETPSTPSKVTSSLQKSILQMKLGLGSQVTGSRVTGTSPTPTLDVIELVARKVCVSGLQTKEQLISAVVRHVPLVDSNRVISQHPYCAQSRQQFFGWNIGKQRAAEWQRAVTARKVIDKVRSSAKKLTLPTPTTREIMDWSRTHGYTPSAFNGPKEDDNYCELCGQKLRAKLRTAHEDCLKFWTANGPPSSCSGSADLCQMLEDSKPSQHADDNDLEVDVISLGQETKVVMKQEPMDEEDDHPRFFLPMSPAAEFVHDTAQKLGVKLEPVETTKDMFSPVLEKMVLKAALLFTNDVLRGALASAYRQNGLSTLRHAPPIILPSHIHQSVSSNPSCDFLSNSHMGVVAMEKEEPPAS
The following text describes a protein:
Function:
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
Sequence:
MIPEMTEVEPVLDFASSGRSGRRNALPDILGSPAGVNPGDLPLKLAELSLKDGPGGVQSPTAEEPPAPPESSEETGES
The following text describes a protein:
Function:
In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets. This form is rapidely lost upon angiogenic or pro-inflammatory activation.
Subcellular Localization:
Chromosome. Cytoplasmic vesicle, secretory vesicle. Nucleus. Secreted.
Sequence:
MKPKMKYSTNKISTAKRKNTASKALCFKLGKSQQKAKEVCHVYFMKLRSGLMIKKEACYFRRETTKRPSLKTGGNHKGHLVLAACQQQSTVECFAFGISGVPKYTRALHDSSITGISPITESLASLSTYNDQSITFALEDESYEIYVEDLKKDKKKDKVLLSYYESQHPSNESGDGVDGKMLMVTLSPTKDFWLQANNKEHSVELHKCEKPLPDQAFFVLHNRPFNCVSFECKTDPGVFIGVKDNHLALIKVDYSENLGSENILFKLSEI
The following text describes a protein:
Function:
Targets proteins containing a FFAT motif to membranes (By similarity). Involved in regulation of phospholipid metabolism.
Miscellaneous:
MISCELLANEOUS: Present with 358 molecules/cell in log phase SD medium.
Subcellular Localization:
Membrane; Single-pass type IV membrane protein.
Domain:
The MSP domain is required for binding to the FFAT motif of target proteins.
Sequence:
MRIVPEKLVFKAPLNKQSTEYIKLENDGEKRVIFKVRTSAPTKYCVRPNVAIIGAHESVNVQIVFLGLPKSTADDEMDQKRDKFLIVTLPIPAAYQNVEDGELLSDWPNLEEQYKDDIVFKKIKIFHSVLPKRKPSGNHDAESARAPSAGNGQSLSSRALLIITVIALLVGWIYY
The following text describes a protein:
Function:
Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MTPNDDDDTKVITFSSDYPDTDYRFLEANQEILDQIKNNKKLVIKGSLTDEAVLCTDDKTFTIRAGHTSNSMLLVSKDTNKIKVALQYHLELTEIQPKLNVLKDLLYSKAIDNSLDFEDDENLLGFSFDEIIDRIQSSEKEIQQYLLKLNTLIYKNRYIVLSENYEFKILELILSEATIGAWKLDNIPIDKCIENIRAPEFIIKHCLQLYSKQKSPTNSGGGGEEIKGGGGDDNNDENICSLDFNKVCIFRAKQLLTLSNKSNMKFEDFMDNWKDTLPIEIQPNFSMLKGIAILIPSSSTNPKEKSVKFINESILPTIPKARFKELFQISTRWSIDDIEPFIKSTIPPGNSLEQFILTYSRPITTSTGEKMIVTRF
The following text describes a protein:
Function:
Receptor for CM101, a polysaccharide produced by group B Streptococcus with antipathoangiogenic properties.
Subcellular Localization:
Basolateral cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Lysosome membrane.
Sequence:
MTDLESPKNGKHLEQVHQNNNEITESEPLTWRFWRKQRYIVVLLAFFGFFNVYSLRVNLSVAIVAMTENRTVFDADGNVSYQQDFPWDSKQKGLILSSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAASHSLEMFLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFLATKYGWESVFYVFGTIGVIWYITWLVFVKAGPELDRFCSKEECDYIQKTIGYVGSKHVKHPWRAIFTSMPFYAIMASHFSENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLAVSGYLADWLQVKGIWTTTQVRRNFNCGAFLAQTVFMMLTAYLLDPTWSVVSLTIAVGLGAFAWSGFAVNHLDIAPQHASVLMGIGNTFATIPGIVSPLLTGYVVTNQTSDEWRIIFFISAGIYLVGCVIYWFYCSGDLQEWAKTPEQKAQEAEEKAQLQLTQTAGFVNSGAELKD
The following text describes a protein:
Function:
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
Sequence:
MRIVFMGTPGFAEVILRALVGDKDIEVVGLFTQMDKPFGRKKELKAPETKTYILENHLNIPIFQPQSLKEPEVQILKDLKPNFIVVVAYGKILPKEVLTIAPCINLHASLLPKYRGASPIHEMILNDNKIYGISTMLMDVELDSGDILESASFLREDYLDLDALSLKLAHMGAALLLSTLKNFSSITRKSQDHMQASFCKKITKSDGLVGFKDAKSLFLKSLAFKSWPEIFLENGLKLLEVELVENEKSHKEGEILEIDEKGVLVGCLKGSVRIARLQAVGKKPLKAKDYLNGKRLKIGGILA
The following text describes a protein:
Function:
Transcription factor that acts as a repressor.
Subcellular Localization:
Nucleus.
Sequence:
MPGSEDLRKGKDQMHSHRKRTMFTKKQLEDLNILFNENPYPNPSLQKEMASKIDIHPTVLQVWFKNHRAKLKKAKCKHIHQKQETPQPPIPEGGVSTSVGLRNADTLPRLPNAAHPIGLVYTGHRVPSFQLILYPNLKVPANDFIGHRIVHFGCCRDPNIYCLYPILESQVCAPSFHSGSPACSSNQSRER
The following text describes a protein:
Function:
Involved in DNA damage-induced apoptosis: following DNA damage, accumulates in the nucleus and forms a complex with p300/EP300, enhancing p300/EP300-mediated p53/TP53 acetylation leading to increase p53/TP53 transcriptional activity. When nuclear, may also act as a component of some chromatin regulator complex that regulates histone 3 'Lys-4' dimethylation (H3K4me2); Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC).
Subcellular Localization:
Cytoplasm, cytosol. Nucleus. Secreted, extracellular exosome.
Sequence:
MLINLKVKTLDARIHEFSIDNELTIRQFKDQIAEKTNIAAENQRIIYQGRVLVDDKQVKEYDVDGKVLHVAERPPFSQRGANARNNDEPMRTFRNVARPPPPGMRTSPYFRALDGMLVGTMAIPVNNGPVAGTRPPPNRYPNSSSFCINRITVALHMIDCADNIAAYLENPAVGLNNQSLDILQRGRWSMESTVVEVGVSSTDLPRNNNIIDMVQDAVTAALSHTGARNYTVVQLPTVYTNENGETSQQRTAEAITSEGAASGAASNASGETTAATVIIEDVIETDDEVADGASDRSVTPTPEPEAEGAVGGQQVTAAETPTSSVGSANDAAAEGGNNSGPRRRTRPQVLAQVIQHYRGVQARLAPFVDRYYEILQNDPTFEESDTDGRENAQRIFDRVSEAFHYLSHAQHAISDLMLDLSQPGPRVLTCRPILVEQSGYIRSNNIFTPNFLAPPSGIINEPFRNRAPGSASAAGTQTATTAGTQTPTSAGTPTAVAPSQAANLQAATDASRSAAAMAEIASRAAGAAAEMAAGAASAAAGAANAAAAAARDLSSDQVEDPIDEPMVGPNAAGAETLAQEQQRLEMDHDHDQAQSETPERETRPVPRLRVYVPVTLPPPNPQLEMARIIQAMVNGQRPNDIHVEFNAPNVMSINLPVHVMTTVRQAPAAGSNETADQSASESSSPESAPASGNGESPNAASTSSGTRSGDQRANTLPTTATQTRSTSRPQIQIGGNNNWGGRIAPTHTAFDRFLPCNSHHIREPEQLLQNNSTSRSTSTAPAGGATVVPPTSAAVTRPVTTGRIQRGSNTIRPMWSSRRQRPASEQLSNLGPAAWAQAQTQTTHIPSAHVGAGSTNGAGVGAGRVRPVGGSTINRDRLATRTAHVGGGSTNGGLPSGRRGRLQAATSRLSRHLPTQLANFLINNMRNNAPTASVGSAVAAVGDTAASPSGEAAPIASTTPAAPLQTVLPTSTPTPRGDSNNLRSQLRTFLNDSLFVGVPINEQTIPGAIGRALDWFGESLVYLPQYERPEYNSRDSVCNILRVSLRLIIELCNGAPAGVDSAQFEQSLKQICDQFRKRLYSVLFLCLGSANAELYWRQLMRLLCAPMRSNFRNEALQFLCIYIDPTIPAQTDTVDAQQFLVLRSIQAAPPTAADEQQLQEQTLDTDVEMSEVTASGSNSSPADELPAVIVGSEPWHMSFPNDWLPVITRDLQTQAEQSNRPQPPFSDAYISGMSAKRRKIIQSEKPTASVECLIANGVQRAIQSVGLGGSNGGSALNASISMDTVIGSIAHDSTIQAAYTDAVRNSLKERTERDVDFKTSKYPQIAKFTEQK
The following text describes a protein:
Function:
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MSNNNNNNNNNNNNNNNNNNNNNNNNNNDKNNNNNIDSSIKEKKLKEWFDKFDVDKDGSLDSNELKKGFKLHANIDMKDEQITKMMERADSNKNHRIEWDEFLKVASDSSSPEIEDIAEHWLQYSTKPIVHAPADVPSWKLLLSGGVAGAVSRTCTSPLERLKILNQVGHMNLEQNAPKYKGRGIIQSLKTMYTTEGFIGFFKGNGTNVIRIAPYSAIQFLSYEKYKNFLLNNNDQTHLTTYENLFVGGAAGVTSLLCTYPLDLIRSRLTVQVFGNKYNGIADTCKMIIREEGVAGLYKGLFASALGVAPYVAINFTTYENLKKTFIPKDTTPTVVQSLTFGAISGATAQTLTYPIDLIRRRLQVQGIGGKDILYNGTFDAFRKIIRDEGVLGLYNGMIPCYLKVIPAISISFCVYEVMKKILKIDSKKISYQS
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Localization:
Nucleus.
Sequence:
MSIVLETSLGDIIIDLHTQVSLAAKNFIKLCKSKFYNGALIYNVQKDYLASIKSVNPATTVYNQPYFEDQINPLLRHNQYGVVATSNSKPHANNSDFYILLTQNAPQLDGKHTIFGQVQEGFEVLQQINRTHIDDDGRPLLNIRIKHTYILDDPFEDIPNMLYPSRSPSPNYKAEGRIEYDEKVLIEEDEEQLLQKTKQHQAKKRAVTLEMLGDLPDADMKPPENVLYVCKLNPITEEKDLEVIFSKFGLIKNCEVVRDWKTGSSLQYAFIEFETIAACEEAYMKMENVIIDERRIHVDFCQSAHQQWSLLKKAQRKKKELNLQRELAQRSKNKDHSFIESLELKKDYFHTKANNDFVIDQQELQKLQDQQLLQLQMQLDSQQKIQQQTQLKQEKQKKEKKNKKKSAEKKNKRHRSSSQGESDSDSQSLKNKKQKDKHKNKNKHKSYDRDDKDQQKRKEKEKLKEQEKQQDLEKQKEIQKQKELEKQQEKEREKEKEREREKEKEREREKEREKEREKEREREREKEKERERKRDREREKEKERLREKEKQREKDREREREKERKRKREKEKEKEKEKEKEKEKEKGKQEEQKLKERQQSKDGGKNKQSESNQDNEGNQKDNSKLKQEQEKQNQTQQNKPPMKSTQKKRQTKSSQSSNDSSSSSSSSSSSDSDSSSESSSSSSSDK
The following text describes a protein:
Function:
Catalyzes the hydroxylation of nicotinate to 6-hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs.
Sequence:
MGKDYQVLGKNKVKVDSLEKVMGTAKFAADYSFPDMLYAGVFRSTVPHARIVSLDLSKARAIDGVEAVLDYHAIPGKNRFGIIIKDEPCLVDDKVRRYGDAIAVVAAQTPDLVQEALDAITIEYEELEGIFTMERALEEDSPAIHGDTNIHQVKHLEYGDVDAAFKQCDIVVEDTYSTHRLTHMFIEPDAGVSYYDNEGMLTVVVSTQNPHYDRGEVAGMLALPNSKVRIIQATTGGGFGGKLDLSVQCHCALLTYHTKKPVKMVRSREESTTVSSKRHPMTMHCKTGATKDGRLQAVQVEMFGDTGAYASYGPAVITRATVHCMGPYVVPNVRVDAKFVYTNNPMSGAFRGFGVPQASVCHEGQMNALAKALGMDPIDIRILNAHQVGAKLATGQVLENSVGLIETLEKAREKAVEVMGYEKTR
The following text describes a protein:
Function:
Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPKTSTPKKKPVAAPPLAANATKTISIPAFVPHKDVDASSLFGRIPAAVWFAAFLLSMLFHLETAPYSKVEESFHTQAVHDLIFYGPHQLAKFDHKLFPGPVKRTFIGSVLLWIATLPITIPVLHMPNLGLYHLLLPHTKIAFQYLVRAVLAATMATSLTCIHTAVRKVHGHLIGGWFSVLCLSQFHLMFWGSRTLSNIFALVCFNMAFAYWIRSNLETKDKKSLPIVTPYFKLMLYFLAFGSIVFRAELALPSGLIITGELFDTQRFTPPAIILIGAVAATASLSITVAIDSYFWEEVGVWPELESFMFNVVEERSKDWGVSSYHSYFTSLVPRIAPLSFAMSFVAWRFSRSAVHRYWRVVYAFLVIYSILAHKEWRFVIYVMPMLNLIAAIGLARLYEMAQGINPIVSYSVDETKQEQSGTVTKDPLQPKPRSPPTLSPRVASLIIFAVKMGCFGLMVMSLGMLYVSSFNYPGGEAFSRVHQIVFERYQGNQASTFECNIHIDTFSAVSGVTRFGECSDHFPVRCTYSKYENHTTSADFVDAGYTYLLTSVPDFHLTATVEGKPVWNILEAVNGYEDISIEPLFEWQMEMVEILSKGEWSNLRLPVKPILSPKVYILSNTLK
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Miscellaneous:
MISCELLANEOUS: Present with 15200 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Sequence:
MKMLTKFESKSTRAKGIAFHPSRPWVLVALFSSTIQLWDYRMGTLLHRFEDHEGPVRGLDFHPTQPIFVSAGDDYTIKVWSLDTNKCLYTLTGHLDYVRTVFFHRELPWIISASDDQTIRIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIWDISGLRKRHSAPGTSSFEEQMSAQQNLLDGSLGDCVVKFILEGHTRGVNWASFHPTLPLIVSGSDDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPHQNLIISVGEDKTLRVWDLDKRTPVKQFKRENDRFWLIAAHPHINLFGAAHDSGIMVFKLDRERPCSFIHQNQLFFVNAEKQIQSFNFQKRVASLPYASLKGIGQPWDAFRSISYNPSQHSVLVNEANGKFALVILPKQPVGAVEPTSVTQDTGNFATFVGRNRFVVYNKNTESVEVRSLENKVTRNIKVEETVRTIVAAGPGSVLVIHPREVILYDVQQGKKVSQLAVKNVKYVSWSLDGQYVALMSKHTITLATKKLELINSMHETIRIKSAAWDETGVLIYSTLNHIRYSLLNGDRGIIKTLEKTLYITKVQGKLVYCLNREGEIEILTIDPTEYRFKKALVNKNFPEVLRLIKDSNLVGQNIISYLQKSGYPEIALQFVQDPHIRFDLALEYGNLDVALDEAKKLNDSSTWERLIQEALAQGNASLAEMIYQTQHSFDKLSFLYLVTGDVNKLSKMQNIAQTREDFGSMLLNTFYNNSTKERSSIFAEGGSLPLAYAVAKANGDEAAASAFLEQAEVDEQDVTLPDQMDASNFVQRPVISKPLEKWPLKEAELSYFEKAVLGQIDDLTIDDETPAVNTTQEQEEPLGEENFNDEDIGEDEGAWDLGDEDLDVGEELPEEVEQGEITSPAQEVETAIWIKNSKLPAVLVAAGAFDAAVQALSKQVGVVKLEPLKKYFTNIYEGCRTYIPSTPCELPAQLGYVRAYDDTVSEDQILPYVPGLDVVNEKMNEGYKNFKLNKPDIAIECFREAIYRITLLMVDDAEDEKLAHKILETAREYILGLSIELERRSLKEGNTVRMLELAAYFTKAKLSPIHRTNALQVAMSQHFKHKNFLQASYFAGEFLKIISSGPRAEQARKIKNKADSMASDAIPIDFDPYAKFDICAATYKPIYEDTPSVSDPLTGSKYVITEKDKIDRIAMISKIGAPASGLRIRV
The following text describes a protein:
Function:
Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.
Subcellular Localization:
Endoplasmic reticulum membrane.
Sequence:
MAADRSNDRYPLHKAVFEGNLRKVSTALRTCDIEERDIHGNTPLHLAVILGRRECVYLLLAHAAPVKVKNDLGWILTGCIAISYGDRHIITSLLKKIKSQTRNEVETRRPQLIDALKELGDFYVEITWDFQSWVPLLSRILPSDTCKIYKRGCSVRMDSTLVDFTDMKWQRGDISFIFNGDANGEHSFAVLDNEKKVFQRLRAEESEAEIEEEVDLLMSSDIVSVYMSTKPITFSRAQGGWFWKADRTEMVGPYLADVYTVNGIMLVSRKRREHLSDEDLVKNKALMDSLSKGGNLIESIPETTRRESLKPPPKPELTWSEYLRYDIDELPHMGRAQVLKEDRKPVKAYVAMSQEFPLSIDLVLKVLEVIAPFKHFSKLKEFVAMKLPPGFPVRFEIPVFPTITAKITFQDFNKCEKIPASIFFIPRDYKEDPNRFPDL
The following text describes a protein:
Function:
MFS-type efflux transporter; part of the gene cluster that mediates the biosynthesis of thethe mycotoxins phomacins, leucine-derived cytochalasans with potent actin polymerization-inhibitory activities and monocot-specific antigerminative activities. PhmH might be involved in the excretion of phomacins (Probable).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MVSGTDTTEVGATTKAPPSEGTEGILDDHSSNSQPQAEKPAKTHYPLSFWLAFLGLCCTGLVSALDGSIVATALPSIIESLDGGDDYPLYGQLADLWGRRYVMIGATIIFILGSGLCGGSSSMNMLIWSRAVQGIGAGGINMLIDMIICDLVPMRERGNFIGLLFLFVSLGATIGPFVGGILTDRASWRWLWLLILLQIFYINLPFGGVALLLLILFLHVKWKNDLSTMERLRRVDVIGNSILIGATFAILYALTYGGTRYTWSDPHIAAPLTIGLVGLVAAFFWEMSPWCKYPVMPPLHFQNRTSAAAFFISFMCMLLAFWINFFYPVYFQAVLIASPTRAGVYTLPRAIAFPLFAAVGGAIVSKTGRYRTVHLVSTGIMPLVMGLSSILDQGSSKAEWVIWQLLFGVSGGMMISTTLQAVQAALPESEVATSVGTWSFVRSLGTIWGLSIPAAIFNNRFDQLSTQFDPSIRALFTRGQAYEHGTAKFIQSFDPETRQIVIQAYIEALKRVWQIGIVFGGVTFLSVFFEKEIHLRTELKTDFGLDEKKKGEVAKEENDVENNGTTVQ
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Sequence:
MPTKYLIAALPVQSAGGDITAAENSLWRSLEDSISQHAIDTPLYRFTVPALKGGTLDSLLALSDDLIRSNLFIEGASHRIRRQIEDLERDGGAGEGGALITVDGVPVDSYLSRFVWDERKYPTKWPLKDIIASILSRIAKIEDEIKVQSSKYNSCKNHLRTIYRKQSVSLVVRDLSNLVKPEDIITSEHLATLLAVVPKYSQNDWLSCYESLDTFVVPRSSKRLYEDDEYALYTVTLFAKVVGNFKAHAQEKGFLIRDFVYSPEAQESKDDLEKLLQDEETMRTSLLELLYARYSEVFSSWMHICAVFVFAESILRYGLSPSILCVVLAPSTESEKKVRNILEEHCGNANSNDFWKSDDDGLGGEIHPYISSTMNVV
The following text describes a protein:
Function:
Enhances the activity of the UidB (GusB) glucuronide transporter, on its own however it has no transport activity. Glucuronide transport does not occur in strain K12 due to a variant at position 100 of the UidB (GusB, AC P0CE44, AC P0CE45) protein.
Subcellular Localization:
Cell outer membrane.
Sequence:
MRKIVAMAVICLTAASGLTSAYAAQLADDEAGLRIRLKNELRRADKPSAGAGRDIYAWVQGGLLDFNSGYYSNIIGVEGGAYYVYKLGARADMSTRWYLDGDKSFGFALGAVKIKPSENSLLKLGRFGTDYSYGSLPYRIPLMAGSSQRTLPTVSEGALGYWALTPNIDLWGMWRSRVFLWTDSTTGIRDEGVYNSQTGKYDKHRARSFLAASWHDDTSRYSLGASVQKDVSNQIQSILEKSIPLDPNYTLKGELLGFYAQLEGLSRNTSQPNETALVSGQLTWNAPWGSVFGSGGYLRHAMNGAVVDTDIGYPFSLSLDRNREGMQSWQLGVNYRLTPQFTLTFAPIVTRGYESSKRDVRIEGTGILGGMNYRVSEGPLQGMNFFLAADKGREKRDGSTLGDRLNYWDVKMSIQYDFMLK
The following text describes a protein:
Function:
Receptor for IL27. Requires IL6ST/GP130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and CNTFR. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Domain:
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding; The box 1 motif is required for JAK interaction and/or activation.
Sequence:
MRGGRGAPFWLWPLPKLALLPLLWVLFQRTRPQGSAGPLQCYGVGPLGDLNCSWEPLGDLGAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLVWGTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPKDVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWARVSAVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSGRCYHLRHKVLPRWVWEKVPDPANSSSGQPHMEQVPEAQPLGDLPILEVEEMEPPPVMESSQPAQATAPLDSGYEKHFLPTPEELGLLGPPRPQVLA
The following text describes a protein:
Function:
Component of the U4/U6.U5 tri-snRNP particle, one of the building blocks of the spliceosome. Required for pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MNKTENLSIEETNEIREKLGMKPIPVFQEKNTDHKESLSIEETNELRASLGLKLIPPQQNFNSSPPNVHNTSKIDELREKITKFQKKANAPLRMAHLLEETNVNDDSSWLENMDAIPSSHESKRSSTLPRKGATKEDENIDLHNVQVSYNIEALSPKKDTILTLKESSIFDDTDSTEVLENVKAAEENADREKLRLRQMNKDRRQKKKILNVSSLDIEEEEEGEKHSITTTHLIIGAEQGVMKAPNTISAKPPTGKVKVNFDSANNMSDEDGGDFKPLKIKKRKIKDPRSTKARKSKITDKMEIVKLVDEDESLSWMEEEQPVTIINPRTSSNNELKGPEDLAREIEKARDEEKRRTESILKMREISNSIVVDEKVTFLNTLDTSLSERSATENKVKVHGEGEKNIGDVTNGHTKEGSGNNTLTEAVNNEPNYEGDAENAPNFFSGLASTLGYLRKKSVFTTGDVDLKPGKDVNNSESLRRDVRNKEHTGTGTYTKDKLHGLEQFTSSDSSNANTHSKRQDHYDPDIKLVYRDEKGNRLTTKEAYKKLSQKFHGTKSNKKKRAKMKSRIEARKNTPENGSLFEFDDN
The following text describes a protein:
Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
Miscellaneous:
MISCELLANEOUS: Present with 6540 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MLKRFPTPILKVYWPFFVAGAAVYYGMSKAADLSSNTKEFINDPRNPRFAKGGKFVEVD
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MEITFRFNETDRAAFTINVPSGGGFTVNFKPVGQLVPPAGGRLNNNGSHVHPQASGGFTINVNPIGLPVPPANGLNVNGAHVHPPSAGGVKEKYESENPKHSDPSLKMANPRVFFDMTVGGKPAGRIVMELFADTTPRTAENFRALCTGEKGIGKFGKPLHYKGTIFHKVFPNYTLCGGDIIGGGEEPGGECIYGSRFFDDENFIKTHSGPGILTMWNCRENTNGSQFMICLRKIVEFDQECVAFGQVVEGLDVIQNIEKEVGRPDLSGVPNKLVVIADCGQIS
The following text describes a protein:
Function:
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Subcellular Localization:
Membrane; Single-pass type III membrane protein.
Sequence:
MAQRCFHSEYFDSLLHACKPCRLRCSNPPAPCQPYCDPSMTSSVRGTYTVLWIFLGLTLVVCLALFTLSFLLRKMNPEALKDKPQSPGHLDGSVQLDKADTERTKSRAGDERILPRSLEYTVEECTCEDCIKSNPKGDSDHFFPLPAMEEGATILVTTKTGDYGKGLQNDDRRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGMKRSRGLALTAAAIKQAAGFTSKTETEPVFWVYVKEVLSKHELQRFYSLHHITADVGRGRAWLRCALNEHSLERYLHMLLADRTRLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNMTSLLKESTQGMSSLLREITASSAVSILIKPEQETDPLPVISKNVHVDARCKRERRRRKKVTNIVSFDDDDEEQGAGDTLKKMPGTAESSEENSDRSSVNIMAAFEGPFGPNSNGSQSSNSWKMDSASLNGELGYQKLDVKSIDDDVDESEEAVYRNPLGRGHTGHKESPDRTLDGNASLPQVHGWAPLQVLHGDADADTDILFPVSGVGSYGTADAPVGSLENGTGTEDHILPEPGLRYREAGSPGRGSPLSSLLPSASVPESMTVHELRQAIVAMMNRKDELEEENGSLRNLLDGEMEHSAALRQEVDALRRKVTEQQERHATKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVVPSLWNVDAEVTVPEQKPGEVAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAYHVYQVYIRIKDDEWNVYRRYTEFRGLHHQLQSAFPQVRAYSFPPKKAIGNKDAKFVEERRKQLQSYLRSVMNKVIQMVPEFAANPKKETLVQLVPFFVDITPPGEPLSKSSRPKVVSRFPKLSRGHPREVRNVEPQSGDL