lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the Mon1-Ccz1 guanyl-nucleotide exchange factor complex specific for Rab7 that promotes the exchange of GDP to GTP, converting Rab7 from an inactive GDP-bound form into an active GTP-bound form. Required for recruitment of Rab7 to endosomal and autophagosomal membranes to mediate endolysosomal and autolysosomal vesicle maturation. Required for fusion of multivesicular bodies and lysosomes but not their formation or trafficking. Involved in the replacement of Rab5 (and possibly Rab4) with Rab7, also known as Rab conversion or the Rab cascade, during endosomal maturation. The Mon1-Ccz1 complex is recruited to phosphatidylinositol 3-phosphate (PtdIns[3]P) enriched membranes by Rab5, which stimulates recruitment and guanyl-nucleotide exchange of Rab7. Together with Rab7 required for autolysosome formation in fat cells and autophagic degradation during starvation-induced basal and developmental autophagy.
Subcellular Localization:
Cytoplasm, cytosol. Note=There is no evidence of association with endosomal membranes, however this association may be transient.
Sequence:
MAKLLQRVEITLRSFYIFNSTFGQVEGEEHKKVLFYHPNDIELNTKIKDVGLSEAIIRFTGTFTSEDDCQALHTQKTTQLFYQPEPGYWLVLVLNVPKEVRLKEGVEVADYRGAEISDRIYRAILRQCYQMFRFQNGCFSSCGSEEPNPDKRRELLCQKLLQFYDQHLTNLRDPAQCDIIDMLHSIQYLPLDKTLFLRAQNFGTLCETFPDIKESIMLYQEQVLCGGKLSPEDLHCVHSYVVQHVLKVEASSSTIAVSPSLKRSISECQVGGFVRSRQKVAGDEHDAVNEEDHPMKVYVTLDKEAKPYYLLIYRALHITLCLFLNADQVAPKQDLYDDLHAYMAPQLTSLARDISSELTKEAVGAAGQDNSSGNSETAPKYLFINEQSLQHHTNFQRHLPQGLPRNVLSIIADLANGSGKAEMESAPAEEVQVKTTNDYWIVKRRCNYRQYYVILCNSKATLLDVTQEARRIFEQELTDDVFFDK
The following text describes a protein:
Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
Sequence:
MSEPQQQQVNLGSLSLEQLQMVREQVEAEIQQLSESIQQLKHASNKYIEAKEAMGGLKGTDGKDMLVPLTSSIYLPGKINSNEKVLVDIGTGYYVEMGIEQGQNFSNRKVQLITEQVNKVQTAINMKRQNLESIVQVAQSKISLYKQQQAQQSQQQVQQK
The following text describes a protein:
Function:
May act as a neurotransmitter or neuromodulator.
Subcellular Localization:
Secreted.
Sequence:
MNSLHAHLLLLAVCCVGYIASSPVIGQDQRSGDSDADVLLAADEMADNGGDNIDKRVERYAFGLGRRAYMYTNGGPGMKRLPVYNFGLGKRSRPYSFGLGKRSDYDYDQDNEIDYRVPPANYLAAERAVRPGRQNKRTTRPQPFNFGLGRR
The following text describes a protein:
Function:
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
Subcellular Localization:
Cytoplasm, nucleoid.
Sequence:
MSKGLAGIMKQAQMMQQKMAKLQEEAANRTAEATAGGGAVTAVVSGKNQIVSLAIKPEAVDPEDVEMLQDLVVTAVNEALKKVQSQFAEEMSKVTGGLNIPGLF
The following text describes a protein:
Function:
Involved in transcriptional regulation by repressing gene expression. Associates with the nucleosome remodeling and histone deacetylase (NuRD) complex, which promotes transcriptional repression by histone deacetylation and nucleosome remodeling.
Subcellular Localization:
Nucleus. Note=Colocalizes with chromatin.
Sequence:
MTDPFCVGGRRLPGSSKSGPGKDGSRKEVRLPMLHDPPKMGMPVVRGGQTVPGQAPLCFDPGSPASDKTEGKKKGRPKAENQALRDIPLSLMNDWKDEFKAHSRVKCPNSGCWLEFPSIYGLKYHYQRCQGGAISDRLAFPCPFCEAAFTSKTQLEKHRIWNHMDRPLPASKPGPISRPVTISRPVGVSKPIGVSKPVTIGKPVGVSKPIGISKPVSVGRPMPVTKAIPVTRPVPVTKPVTVSRPMPVTKAMPVTKPITVTKSVPVTKPVPVTKPITVTKLVTVTKPVPVTKPVTVSRPIVVSKPVTVSRPIAISRHTPPCKMVLLTRSENKAPRATGRNSGKKRAADSLDTCPIPPKQARPENGEYGPSSMGQSSAFQLSADTSSGSLSPGSRPSGGMEALKAAGPASPPEEDPERTKHRRKQKTPKKFTGEQPSISGTFGLKGLVKAEDKARVHRSKKQEGPGPEDARKKVPAAPITVSKEAPAPVAHPAPGGPEEQWQRAIHERGEAVCPTCNVVTRKTLVGLKKHMEVCQKLQDALKCQHCRKQFKSKAGLNYHTMAEHSAKPSDAEASEGGEQEERERLRKVLKQMGRLRCPQEGCGAAFSSLMGYQYHQRRCGKPPCEVDSPSFPCTHCGKTYRSKAGHDYHVRSEHTAPPPEEPTDKSPEAEDPLGVERTPSGRVRRTSAQVAVFHLQEIAEDELARDWTKRRMKDDLVPETARLNYTRPGLPTLNPQLLEAWKNEVKEKGHVNCPNDCCEAIYSSVSGLKAHLASCSKGAHLAGKYRCLLCPKEFSSESGVKYHILKTHAENWFRTSADPPPKHRSQDSLVPKKEKKKNLAGGKKRGRKPKERTPEEPVAKLPPRRDDWPPGCRDKGARGSTGRKVGVSKAPEK
The following text describes a protein:
Function:
Transcription factor probably involved in vascular development and shoot tissue organization. Binds to the DNA sequence 5'-CCGAGTGTGCCCCTGG-3' present in the promoter region Box II of the phloem-specific rice tungro bacilliform virus (RTBV) promoter. May regulate tissue-specific expression of the RTBV promoter and virus replication.
Subcellular Localization:
Nucleus.
Sequence:
MVNLVTYKVCNDPAEQNTILTTCYLPPSLHRPRSRLSTRISFFFFFLLLHLRFFLTTMDQTNPFDPRFGRFPSSGNTIVGGNSSTASPSVSAVGLKHDPISYSTTPPPSARGGYHRRAHSENFLRISEDFLFDSDTDFSLADIDFSSLSDENGANSGGLFPPNSAAEVACVKESEKKGKRKSSERPTSGAHLRSLSVDTALFEGLGLSEQGGGITGSGSGEGGGGMGNTIRHRHSSSMDGLNSPFEAESPEPMDYTKKAMAADKLAELALLDPKRAKRILANRQSAARSKERKIRYMSELERKVQTLQTEATTLSAQLTLLQRDTSELTTENKELKLRLQAMEQQAHLREALNQALRDEVQRLKIATGQVPALNNGNGNGVHHQIPQNYFPYPQQNQHQHQHGGGGGQAPVDSMEFM
The following text describes a protein:
Function:
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Membrane; Peripheral membrane protein.
Sequence:
MTEIEKVNNETKKLSKSYFDVLGICCTSEVALVEKILNNLEGVKEVSVIVTTKTVIVHHDSLLISQQQIVKALNQAGLEASIRVNGEKNYQKKWPSPFAIVAGSIVLRDYWEAATIVFLFTIAEWLESRASHKATAVMSSLVNIVPPTAVLAESGEVVNVDQVKLNSILAVKAGETIPIDGIVVVGECDVDEKTLTGESFPVTKQKDSRVWAGTTNLNSYISVKTTALAEDCAVARMAKLVEDAQNKKSKTQRYVDKCAKYYTPAIVVIAACLTIVPAALRLHNRKEWYRVSLVALVSACPCALVLSTPVAMSCALSKAAISGLLFKGAEYLETLAKIKIMAFDKTGTITRGEFAVTEFRSLIDDLSLSTLLYWVSSIESKSGHPMAAALVDYAQSNSVEPRPDRVEQFQIFPGEGIHGRIDGMEIYVGNRKISSRAGCTTVPEIEGDSLQGKSVGYVFLGSSPAGLFSLSDVCRTGVKDAMRELKQMGIKTVMLTGDCYAAANHVQDQLGEALDEFQAELLPEDKVTIIKGFQKEAPTAMIGDGLNDAPALATSDIGISMGISGSALAKETGHVILMTNDIGRIPKAARLARRVRRKVIENMLISISAKVAIVALAIAGHPLVWAAVLADAGTCLLVILNSMLLLRGATRRHRKNCCKSSTASIAHCHKNKASCCKSEKDPQLCFSDIESQDNCGKKSCLSEVCVPRCQPVSSGSQSCRNNQSSDSIQNTGLHSHPHPHCCSSKMSVTPCQSAVSESKSCGSKSCSDSIHKSCCHSLTNSHIYSSQMSSPRCHSATSSSKSCVSTKSSNITEKNCCRSHEIPQTCSTKMSSPGCQSAISGPKSCGNSKCSDSRDNNSCLSHPNHQTCTSKVCAQPSPSATSSTRTCGNTKCLDTSSKNSCHLHANSEQYSSKMSGPTCQNVNSGSRSCGNNKCLDSATEHGVHSLNDPLYEEKILEKKILDLVRADLESNHDVIHGCSDEERDHHPDLDKAYDSCALQECCYSVQGNITDVSETGMQETAHCYSTNHQCQAVVSGSVTCRNNKSLDSLDNHGCHSHAHPPHKEKDVEEPHHSVGHGCSDKGHDHSHPEKAYDNCGPQDCCFPVQGHGIEISKSGSQETAHFDSIKQSMVISSSCKHTPKDQVAHCGFHSRTTPTDEELAKLVRRCCKYRSCHDVHSGCRKHAAKCGPAVRSTINILRDNHHHHHHLDCSRRMVCLPLEKRHIGGCCESFRKECCPKNNHLASSFGGGLSEIVIE
The following text describes a protein:
Function:
Could be required for the biogenesis of the putative YbgD fimbria.
Subcellular Localization:
Periplasm.
Sequence:
MTFIKGLPLMLLTISLGCNAAVQPDRTRIVFNANDKATSLRIENQSDKLPYLAYSWIENEKGEKSDALLVALPPIQRLEPKATSQVRVVKQASTTQLPGDRETLFFYNMREIPPAPDKSSDHAILQVAIQSRIKLFWRPAALRKKAGEKVELQLQVSQQGNQLTLKNPTAYYLTIAYLGRNEKGVLPGFKTVMVAPFSTVNTNTGSYSGSQFYLGYMDDYGALRMTTLNCSGQCRLQAVEAK
The following text describes a protein:
Function:
Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKHPFEQFNLESSLIDAVKDLNFEKPTEIQNRIIPRILKRTNLIGQSQTGTGKSHAFLLPLMQLIDSEIKEPQAIVVAPTRELAQQLYDAANHLSQFKAGVSVKVFIGGTDIEKDRQRCNAQPQLIIGTPTRINDLAKTGHLHVHLASYLVIDEADLMIDLGLIEDVDYIAARLEDNANIAVFSATIPQQLQPFLNKYLSHPEYVAVDSKKQNKKNIEFYLIPTKGAAKVEKTLNLIDILNPYLCIIFCNSRDNANDLARSLNEAGIKVGMIHGGLTPRERKQQMKRIRNLEFQYVIASDLASRGIDIEGVSHVINFDVPNDIDFFTHRVGRTGRGNYKGVAITLYSPDEEHNISLIEDRGFVFNTVDIKDGELKEVKAHNQRQARMRKDDHLTNQVKNKVRSKIKNKVKPGYKKKFKQEVEKMKRQERKQFSKQQNRQKRKQNKKG
The following text describes a protein:
Function:
Plays a role in regulating the structure of the Golgi apparatus.
Subcellular Localization:
Golgi apparatus, trans-Golgi network. Cell junction, tight junction. Cell membrane; Peripheral membrane protein. Note=Recruited to tight junctions (TJ) during late stages of maturation of the TJ complexes. Excluded from adherens junctions and desmosomes.
Sequence:
MSSAAPAKKPYRKAPPEHRELRLEIPVSRLEQEESLTDAERMKLLQQENEELRKRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHALASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDARNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHKLADLPCELQDMVRKHLRSGQEVASPSPSPSSSLSPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSGGDPASPPAPGSPNGECCSVSTAGGSPEEELPLPAFDKLSPYPTPSPPHPLYPGRKVIEFSEDKIRIPRNSPLPNCTYATRQAISLSLVEDGSERAHRSSVPSSPASAQGSPHHQPSPAPSALSAPASSASSEEDLLASWQRAFVDRTPPPAAVVQRTAFGRDSLPELQLHFSPGHSTAPPPSPHRERGLVLPAEPDSGFPQDEEEEMLNLPVSPEEERQSLLPDKEGTEEASGPSHVDGRAWPLPSPSRPQRSPKRMGVHHLHRKDSLTQAQEQGTVLS
The following text describes a protein:
Function:
Plays a role in development of both male and female reproductive tissues.
Subcellular Localization:
Nucleus.
Domain:
The cysteine-rich domain CRC binds zinc in vitro.
Sequence:
MDTPQKSITQIGTPISKSRFEDSPVFNYINSLSPIRPVRSIPNPNQFSSLNFTSPPSVFTSPHLTSSHKESRFFKTHNSSSSDPTNSVESQEDESTSHEEVPAEGEDTKGLNIDDCMREEASVETNLDDSVASPCGGNTTDLSLVPYAPTRGEDGSCEDNGMELQKMHDNVQGKTETPDWESLIADASELLIFDSPDASEAFRCFMMQRASNSEARFRNGVEKQTMQHDSNKEPESANAIPYEAVSLLHRGIRRRCLDFEMPGNKQTSSENNTAACESSSRCVVPSIGLHLNAILMSSKDCKTNVTQDYSCSANIQVGLQRSISTLQDSLDQTENEIREDADQDVPVEPALQELNLSSPKKKRVKLDSGEGESCKRCNCKKSKCLKLYCECFAAGVYCIEPCSCIDCFNKPIHEDVVLATRKQIESRNPLAFAPKVIRNSDSVQETGDDASKTPASARHKRGCNCKKSNCLKKYCECYQGGVGCSINCRCEGCKNAFGRKDGSSIDMEAEQEEENETSEKSRTAKSQQNTEVLMRKDMSSALPTTPTPIYRPELVQLPFSSSKNRMPPPQSLLGGGSSSGIFNSQYLRKPDISLSQSRIEKSFETVAVDGAEQMPEILIHSPIPNIKSVSPNGKRVSPPHMESSSSGSILGRRNGGRKLILQSIPSFPSLTPQH
The following text describes a protein:
Function:
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine (By similarity). Possibly implicated in influencing the macrophage autophagy pathway.
Sequence:
MFGFVSDLLTAAVSSLDELLQDTPAHQIILGTAALYFLYNQYHNPSISRWYRSRNNASMKQRIIDSAYALAKNLPGVNQIIEKELNKELSSTREKLRIQRSGMTLREEIPEEGLSPQDILSAFDVDVEKCHFDFLSVTNDSPEREFLVERGDGKDSGALYAIHPKELTELLKEVYGATALTNPLHDKWPRINAMQAEVIRWCQNLFHGSKECYGLLTHGGTTSIIEAMAAYVIRARAKGIDYPEIVVPETAHAAFKKAAELTGAILITVPVDKKTGAVNPKVMSSYITRNTAVIVGSAPSFMNGIHDPVSELGQLAKKKNVPFHVDACLGGFLTAFLDTSSEPMDFRVPGVTSISADLHKYGCCPKGTSVCLFSEDSPALSVYAALNWSGGLYATPGILDGSTSGARVAEVYATLSYYGKNKYQEIAKSIITLRNAIQKELTTLLEEGNGLTSEDIYVYGNPQWSILGFRSNTCNAHFIADELEKRGWKLNLLQNPDGFHLCLTHVHTLVKGFETQFIKDLREAVIDVKNYPPGKKPSGNVKVYGAVGMMPIELQREICKQYQKARLNYTSASPGSLRIFTNVPVEEDEGLRNRKTEKYKV
The following text describes a protein:
Function:
Involved in protein precursor import into chloroplasts. Part of the motor complex consisting of a co-chaperone (TIC40) and a chaperone (HSP93) associated with the import channel (TIC110). Causes the release of bound transit peptides from TIC110 and stimulates ATP hydrolysis by HSP93. Involved in reinsertion of proteins from the chloroplast stroma into the inner membrane.
Subcellular Localization:
Plastid, chloroplast inner membrane; Single-pass membrane protein.
Sequence:
MPPPAPYYPGMPADAAARQQYYMAAPAAAYYPPPPAPYKEEPASTGAPWWIWLGAGVILGQVLAKVQEYMKNPKTPQQIMMEMAMKQMSGAMGSPPGGAGMPPFGGPGSPFGGAAPGANPFAGAAPGANPFANFAAAAAAGPSTVDTTASPAFAGASSSGASSSERKGEKFASRLNSEGREPRKPEPAPAAAAAGAAAAASSATKPLDVVEPVVKEPSSSGSSSGASSSGRSSFFADVDAEASSRAGGTSSSSGSGAAPQDTGVMTDMMESMLRNPEMQKMLYPYLPEPMRNPQSIEWMLSNPEVKKQMEQMFASQNVMSPQMMDMMKGMDFNQDKVNKQFAELGLKPEDVISKVMANPDLAAGFSNPKVQAAIMDISQNPMNIVKYQTDPEIMKVLEKVTEIFQPQMGGQK
The following text describes a protein:
Function:
Putative Notch ligand involved in the mediation of Notch signaling. May have a role in neurogenesis in the peripheral nervous system, limb development and in the adult brain.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
GACCDGDGRTTRAGGCGRDECDTYVRVCLKEYQAKVTPTGPCSYGYGATPVLGSNSFYLPPAGAAGDRARARSRTGGHQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPDEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSCVEPWHCDCETNWGGLLCDKDLNYCGSHHPCVNGGTCINAEPDQYLCACPDGYLGKNCERAEHACASNPCANGGSCHEVLSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCLPGWKGANCHININDCHGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELEYYKCASSPCRRGGICEDLVDGFRCHCPRGLSGPLCEVDVDLWCEPNPCLNGARCYNLEDDYYCACPEDFGGKNCSVPRETCPGGACRVIDGCGFEAGSRAHGAAPSGVCGPHGHCVSLPGGNFSCICDSGFTGTYCHENIDDCMGQPCRNGGTCIDEVDSFACFCPSGWEGELCDINPNDCLPDPCHSRGRCYDLVNDFYCVCDDGWKDKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCTIAKNSSCVPNPCVNGGTCVGSGDSFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRSGPRCQEVVIFTRPCWSRGVSFPHGSSWVEDCNSCRCLDGHRDCSKVWCGWKPCLLSPQPSALSAQCPPGQQCREKAMGQCLQPPCENWGECTAEDPLPPSTPCLPRTTHLDNNCARLTLHFNRDQVPQGTTVGAICSGIRALPATRAAARDRLLLLLCDRASSGASAVEVAVSFSPARDLPDSSLIQSTAHAIVAAITQRGNSSLLLAVTEVKVETVVMGGSSTGLLVPVLCSVFSVLWLACMVICVWWTRKRRKERERSRLPRDESANNQWAPLNPIRNPIERPGSSGLGTGGHKDVLYQCKNFTPPPRRAGEALPGPASHGAGGEDEEDEELSRGDGRLSRSREVPLTQIHQRPQLLPGKASLLAPGPKVDNRAVRSTKDVRCAGRE
The following text describes a protein:
Function:
Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
Sequence:
MDAGLKRELEQKVRSGERLTREDGIALYESDDLAWLGGLAHEVRTRKNGDVVHFNVNRHLNMTNVCTASCAYCSFQRKPGEKDAYTMRIEEAVKLAKAMEGENLTELHIVNGLHPNLPWRYYPRSLRELKAALPEVSLKAFTATEIHHFETISGMSASDILDELIDAGLESLTGGGAEIFDWEVRQHIVDHRTHWEDWSRIHRLAHEKGLKTPCTMLYGHIEEPRHRVDHVLRLRELQDETGGFQVFIPLRYQHDFVDMKDGKVRNRLQARTQMATGAEALKTFAVSRLLFDNVPHVKVFWVMHGVQTAQLALQHGADDMDGSVVEYKITHDADDFGTPNKLTREDLLDLIRDAGFRPVERNTRYEILREYEGPDPARRESPQPMRV
The following text describes a protein:
Function:
Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion.
Subcellular Localization:
Cell membrane, sarcolemma; Single-pass type IV membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MTSMAILTCRPNSHPFQERRVPLTEAMKIGRSVARARPAPNNCIFDCKVLSRNHALLWFENSKFFLQDTKSSNGTFVNNQRLSKGSEESPAHEIHSGDIIQFGVDVMENSRKVTHGCIIAQIHLYNPDGTEFKPRNGMAPGPPLQLMGPPSVIQIQAQDLYQLQQYLQEAAHREQMLENKLATLQRVMAETQEASESSWQALIDEDRLLSRLEVLESQLQAFAKNQTEESLRKELVALQEDKHTYENTAKESLRRIFQEKLEIVTKLSDTERTCSNVEDECTHLKESYEMSQEELKALAAKHSDKLKDLQELSEKMRDAERNHDEVTRKTNQDKEELEKRIKDLSSKEENLLAKLEALQAENDFSKEQLSAMKTRLEQNQDSERERPVEDQEVQVDISTVNNNEDDEPDITIPITVQLDYLNNVEMADASADALTSQDFTETTDRLKEIVHFKASLLEKEEMLEQSRQRMEDFKGQLDRAQEDANTSAQQVADLEEKLSSFEDRAEELVESALTEIRRQLEESKLQNEAKNEIIKQLKDKLSQSERQNLQWLRRDLVQKETMGTELNNHVHGNTSCVQTEEMQLDSSCTTEQVQRLRDELVETKETLRRTEERLSKSAELEARLRPVTSNSELQTEETATQNGSVDDISFEDKSELEELRAELTAAQGDTQQRLEEIRQLREQLQEAQSIARERSNHCFELQDQLNKAEGTAHDVKQQILALRDRLIDEERASKENHQEAKNLKEQLDRVQQSSKESQNEAEKVRGQLQECQCELERLKGMQDNKDNRVRKNNEQGGKHKEMSYKEECSLRKRIQSLEEDLNRARKETTKLTTEVNRLEAANRELDMKYQAQKDKTDNKAIEWRMELNEAHREADKSRQECGSARTEVELLQEKLKNSQRETDKLKDDLKGLKVEYKMVATSSRNVSGLGVDRGVTHGLMYLCLVPMGILAAAMMFALFPALLSILSGEL
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MSNKLGYDVTDPTVQLLRASAFMQNGPVKQVRSLEDLDRWVRSQAYYDIIAYISNTSKAIQGHRLTQTFPVTEQMRRLSEIFDGLDHLIVEHTPKIEDSYLALPFGQVRSKAYRTWMREMYQHVFSKLDEAINVNCKHINELGQYLRRSFGNGNTLDFGPANELMFLFFLCGLFRAGILLAKDTVAAALMLFNRYVNVVRRLISTYGLTIAKDPACTIEDYYFLPYLWGAAQLSVDSPFSPMQCEQGKIMDNYRQDFMMLEIIDHLQKTRSGPLSRVALQLWSILSIPTWPQVYRGLERNYIDHVLSSFGTVEQAIFCELMSFEAVVPIMPLQRAHLGTHLIVDEKENEDELEQKYGENRWSLSPPVSRYVSMEPESFLGFQASKTHNKSKESEDERLWMMRQLVDENDPNSDMFFPDREVKGRDSLTSFAN
The following text describes a protein:
Function:
Probable transcription factor that binds specific DNA sequence.
Subcellular Localization:
Nucleus.
Sequence:
MSGNSEGLLESSGGGVGGSVEEEKDMKMEETGEGAGSGGNRWPRPETLALLRIRSEMDKAFRDSTLKAPLWEEISRKMMELGYKRSSKKCKEKFENVYKYHKRTKEGRTGKSEGKTYRFFEELEAFETLSSYQPEPESQPAKSSAVITNAPATSSLIPWISSSNPSTEKSSSPLKHHHQVSVQPITTNPTFLAKQPSSTTPFPFYSSNNTTTVSQPPISNDLMNNVSSLNLFSSSTSSSTASDEEEDHHQVKSSRKKRKYWKGLFTKLTKELMEKQEKMQKRFLETLEYREKERISREEAWRVQEIGRINREHETLIHERSNAAAKDAAIISFLHKISGGQPQQPQQHNHKPSQRKQYQSDHSITFESKEPRAVLLDTTIKMGNYDNNHSVSPSSSRWPKTEVEALIRIRKNLEANYQENGTKGPLWEEISAGMRRLGYNRSAKRCKEKWENINKYFKKVKESNKKRPLDSKTCPYFHQLEALYNERNKSGAMPLPLPLMVTPQRQLLLSQETQTEFETDQREKVGDKEDEEEGESEEDEYDEEEEGEGDNETSEFEIVLNKTSSPMDINNNLFT
The following text describes a protein:
Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Sequence:
MASSGEDISNDDDDMHPAAAGMADGVHLLGFSDEILLHILSHVPSTDLILNVRRTCRKLAALCLDKSLIHTVLLQKDYQASEDKVRQLVKEIGREIQQLSMAGCYWLPGSTVEHVARCRSLVKVNLSGCHLTSLRLSKMLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLFTPSYGVVPCCTSLEKLLLYFEILDRTREGAILSGQLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPQNLHAFLISVPGSFAESGATKNLLDSMARNVVLDALQLPKSWLNGSSLLQHMKFNNPFYFSFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCVHCLSPDSLLRKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRHLCQLLARLRHLRSLSLPVCSVADSAPRADRAPAQPAMHAVPRGFGKKVRVGVQSCPSPFSGQACPQPSSVFWSLLKNLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQLPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRLRDLRLEQPYFSANAQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLFTGESLATCKSLQQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPLVHLDEITLFKSRVAEEPPNLWW
The following text describes a protein:
Function:
Seminal fluid metalloprotease which is transferred to females during mating and is required for processing of two other seminal fluid proteins Acp26Aa and Acp36DE in mated females.
Subcellular Localization:
Secreted. Note=Secreted into seminal fluid.
Sequence:
MFPQIWGVIFLFTPTVFSELFKDPELLAGFYQGDIKAHPIRTRNGIVNQIYHWPNRTVPYMIEDDAFADSHYREILRAISIIEENSCVIFKPATEMDFPMALVITSKGLGCNTVHLGYRNKTQVVNLEIYPLGEGCFRIGSIIHELLHVLGFEHQHVSQNRDQYVSIQWKNINPQYNINFVNNDNSTAWHDFDEGYDYESVMHYVPRAFSRNGQPTIVPLREGAENMGQRFYMSEKDIRKLNKMYRCPDHV
The following text describes a protein:
Function:
Component of the MMS22L-TONSL complex, a complex that promotes homologous recombination-mediated repair of double-strand breaks (DSBs) at stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication. It mediates the assembly of RAD51 filaments on single-stranded DNA (ssDNA): the MMS22L-TONSL complex is recruited to DSBs following histone replacement by histone chaperones and eviction of the replication protein A complex (RPA/RP-A) from DSBs. Following recruitment to DSBs, the TONSL-MMS22L complex promotes recruitment of RAD51 filaments and subsequent homologous recombination. Within the complex, TONSL acts as a histone reader, which recognizes and binds newly synthesized histones following their replacement by histone chaperones.
Subcellular Localization:
Nucleus. Chromosome. Cytoplasm. Note=Mainly nuclear. Localizes to DNA damage sites, accumulates at stressed replication forks. Recruited to stalled or collapsed replication forks following histone replacement by histone chaperones: TONSL acts as a histone reader that recognizes and binds newly synthesized histones.
Sequence:
MTSTKEIKQLQKAKSKAQSSNNLKEEASLCNQLGEVYAKTGDYQAAIEEHRQELALSEILHDVIGSAVANRKIGECYAELGNIEAALKHQRLHLNLARSVHDAAEEQRALATIGRTYLFLFDSDQSANSLKHAEDAFKRSLAIVDERLEGTVSPREISEMKARLLLNLGCVYDGMKEPQRCSDLIRQSIYIAEKNNLLEDLYRANFNLGSIHFRNGQHSRAMRCFEQSKECARKMKDKFSESECFHSIGKILLHLGDFSAARRSLKKAFCLGSQQPSDREAVKKDFRHAIRGCQLEQTAAEVTQKFSHEALDLSEQLGDLYCKVGCYSKALEAYQTQLACAEALAKPARELAVIHVSLAATYTDLRQHHRAVEHYRQELQLRKGNPKEECETWLNMAVCQEEMCQSMETLDHCFTSALNCAEKSGLNKLQRRVLRVWLQAQRRCGSSQCDDTEARLMELCERDGLSLDQSEDEDEEDEVDNSEPLEDSDIQYSESDDEDLEGYDKMVTGRRKTQRWNRRNEKGETVLHRACIEGNLKQVQYLIEQGHPVNVRDYCGWTPLHESCNYGHQEIVAFLLDRGANVNDPGGRECGGITPLHDTLSCGHFSVARLLVLRGASVTVRNSKGHTPLDTLRQWFKTYSGQLDPETKQECLETEKLIKRALSGDVSVVCAAPRQQKELQDSQLFDAEYSEPLLRESPPSPPPITRPAATVPTSKDSAPKHRSTSASTRRPRGMEVDVLYGDDSSSSDNPDSDCSLSPLRPVRSRPRSPPAQSPQEVPSSQELPSVYGIKETTVPPQSESGRLEYQKAMQNLGSAKSRLFSQSLSDPAFTSTPAVSANSRAALVPEDQYLADDWLEDDLIDMQPKKKRRVSEHNATRETTSRSQNNSSTIAEVPPRVQSCSSRGSLSLKKGSNKPRQVKMNQLPGMVMLGRREVSRSQSPIMTQESDHIQEPAPPSHQAMPPASFQNRAAHVPAPIRMRVKVQDNVFLIPVPHSEADSCTVAWLCDQAAQRYYQMCGLLPRLSLQKEGALLLPTDPLLAVLHTNEEVLAEVCSWDLPPLPERYRKACESLGVEENRRVSRVCEVQDSSSCVSVCGLSLSPASLNPLLRALKLQASLTELRISANRLNDELLPEMMAAAATMPRLRVLDISANQITGEGLRKASDAFETRSQAAFPCLEELNLSMNPLGDGWTQALASLLSSCPLLSSLSLQACGLSARFLQQHRLLLANAMASTGNMRSVCLSHNALGSTGFELVLKTLPMHCLTHLELSAVCRGPSDQPSMEILTKLLAQGDCPLTHLNLSGNGLTDHSVLLLARCLPVCPSLVSLDLSANPLVTSTGLHSLLNGLVEARRPLGHLNLQGCQVSGPLAEDCLDSLSDHIRDLRLCSQSLNKLDQDALQQSWKRRTEAVHIFSRNSKCMLSISSPSH
The following text describes a protein:
Function:
CTP-dependent diacylglycerol kinase that catalyzes the phosphorylation of diacylglycerol (DAG) to phosphatidate (PA). Controls phosphatidate levels at the nuclear envelope. May be involved in vesicle trafficking between the endoplasmic reticulum and the Golgi apparatus.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Sequence:
MANEEELQTAESAFVTGARRYSNDYSESESSSKHSGCSTPVEGTPAEAATTIGARASGGSTTWQRLRQLLMERGSDVHLPVTEIHLKSQEWFGDFITKHEVPRKVFHSSIGFFTLALYVRDVDYRNVRLPLIVGFVHVLLLDVIRLHWPAFNTLYCQVTGLLMRKKEVHTYNGVLWYLLGLIFAFSFFSKDVALVSLFLLSWCDTAASTVGRLYGHLTPRISRNKSLAGSLAAFVVGVISCAVFYGYFVPAYSHVNHPGEIMWNPETSRLSLVQLSLLGGFVASLSEGIDLFNWDDNFTIPVLSAIFMHTIIAFSQR
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
RVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGETEGTCITHAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRTASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPTDFHIELRIKRDRGYHTEVRKNTQDGSYPIDAVSMPVRNVNYSIFACGNGNAKYEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHTEEEGTRFQENKNRFTSPLLSFQKRLTNLKKNKKRIPLNCIFIDQLELPSRTYNCLKRANIHTLLDLLSKTEEDLMRIDSFRMQDGKQIWDTLEKHLPMDLPKNKF
The following text describes a protein:
Function:
Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MYGKIIFVLLLSEIVSISASSTTEVAMHTSTSSSVTKSYISSQTNDKHKGDTYPATLGAHEVSEISVTTVYPPEEDNGEWVQPVHPFSRPAPVVIILIILCVMAGVIGTILLISYGIRLLIKA
The following text describes a protein:
Function:
Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton.
Sequence:
EKDEFGNRTQEEYEDDFEKDLDWLINEEGKSENEDPEGENDIESQIDKELEEEEEKTRGELLEIKSLNPAEPDPGGAADGNGDLGGGGSPPSPAEPSEGLSDTDSEGSHQRLRPEEGVDEDELDEEAKKYIMEKIQQANRQLEDEEPADETRERRLKFKDKLVDLVVPPADYEAGRDGEGDVSGPMSRLQISEKIGGARGSPREGKVLVEKDGKFDLVSLREVESQGLLPPLPCASGEPDGGWQTSPRPPSGHGEPCPAHGWAGGSSPEAGHVPRPPPVPKARPNSAGHSQGRTRKRTATRRAQSASNPPGHTTYTLSPEQKELRLKLEQRRERLRREEEAKKREEEEQKRQENELAFRAWLMQKKEQLQEQRRIVRAKEMERMNNRPEHPDPQEAFKLWLKRKHVQQLRERQMEEMKRLEEESTYYIHDREECERAFKLWLKRKRAEKRTERLAARERSRRLVMEARRAQRKQDLLCTISEAKSSRFIDNYG
The following text describes a protein:
Function:
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Sequence:
ESCFDSISVHWDMESLLSLLRFTFGCSLDLTSENFLPLYEAALFFGVDKLLLVCRSWLDYVTSEVRIRPPQLRLEDLVLIWDYGRENAIDFIPQLTGYLARNFIWMASCDSFHNIPFELLLSCVKHPCLTVDSEMHLCDAILLWLAANTKPSDLLSSTGDSRLEILREIRTGLLSLPFAAGKRRCPFFSKFAERSVVAICSLATSRSFSLADILGGGDCKLRIRLTEYTKVLDLSGCPQISLPLLLLDMLPSSNNLDKMLMKKLNQLSLKLERHMDISRIQWDIFPVLTFEAVQVVDVSNCSVLHLEAAIECFSKSFPSLTTLKAAYILNFRTMMLYQLLQRCPLLSDIDLIVDSTPVIPAKVSVIASFPDVTLQISTSSSDETYASVPVFHFSGQLSNITKLILEGRTDIYDSDLHNIAECCPFLCCINLNACTSITDSGISILVLKCIELHSIYACDTSFGHNCVLSLCCSISRFDAVEMKMADRTNSLAYKLQILHIGGCKGINEISLLELISQTHRIRSLCLRETQLVDNSLYKFSGSSLEMLDVSDTKVSFHAVGHVVRGNPYLKCLIARGCRHLLQEENDTLENSPVLSYNCPVFYYELGKSCNLEEISLGWGFSFFSLEALRPAIKMLKTFIVGLGGSLGEDGLKLVPTFCPWLETLILYFQVISDSVVRNILGTLKNLQVLALCYCFGEISSLSFQSSAPRLRKLKLERVSAHMTNDDLLILTQNCMNLTELSLVGCRRLNSDSGFLSFLKDFLSQDLKVQVMANGVNGVEMGGGSTSSAGVVTAMDYNHPFFLSPTDVSGRNKLGLVHGSCTKEKISSELGNHGERVNAIVLSWIMNSVSKELLGGIMYASVASVVWNELFERFNKVDDARTFNLHKEIATLSQGTTPMSFSKLKDLWEEFEALVPAPGCDCEKSKEVVLHLQKLKLFQFLMGLNETYTQARSQILLMTPLPTVNQAYAMIMGDESHKAVATNAGVLGSGPAGAGGSLDLAMFTNGTQKFKKNYNL