lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.
Subcellular Localization:
Nucleus.
Sequence:
MDPSIFKLLEEDEDESMHSGADVDAFQAALNRDIEGSASLPTVQGNSQSPTEQFTTWTNGIRDSTINLHTQMKEQLQGSRVENQHQRADESHSQDLLHQAGQRWENPSQVPHPTEKNLTGNQVSESQYSKLQKMSSQQARGVEQPVNPINRNPKQVPFAALLPTLISQLDKDRAMQLRTLYSRLKKNEIPKEGFTRHVKEIVGDQMLRMAVSKLQQVGLNQGKMGIQAPTEINNKKSESDPRGVVLLNQLPPSTGSSVPVQGFTNHPQHNQMQRPPSSFPMYTSSGSFHSFPGPSTNVSGSSLRPHLHDSHMRHVALNQAVGSTGLGAPSQSTTNMMTAPKFERPASVNDPSRVQGGATSHFQNSSSLPLNSVPSQGSSLSHVKQESVEQSFEQNKAAPGTSKEDLEKESCRMVLSAPSNIDANTSMNARGPLGTSQAGFNARMPPKKPTVGQKKPLETLGSSPPPPSKKQKVVQNSMDQSIEQLNDVTAVSGVNLREEEEQLFSGGKEDSRVSEASRRVVHEEEERLILQKSPLHKMLAEIMAKVGLKQISNDVERCLSLCVEERMRGLLSHIIRLSKQRVDTEKSRHRTFITSDIRLQINEMNHKMKEEWEKKQAEAEKLKKSSESEEGDGGVDSEKEKEDNRSKGLKGNKEDDDKMRATAANVAARAAVGGDDTFLKWQLMAEARQKSVSETGKDGNQKTTSGGGRNSKERQDGGRRFSGPGGRRLGKNQGPSLQPKVVRTISVKDVVAVLEREPQMSKSTLMYRLIQ
The following text describes a protein:
Function:
May act as an angiogenesis inhibitor.
Subcellular Localization:
Secreted.
Domain:
The C-terminal AMOP domain plays an important role in the anti-angiogenic function of ISM1.
Sequence:
MLRLAAELLLLLGLLLLTLHITVLRGSPDSSSNSSHSLIQNEPSSDSFSFNPSDRQEYLDEATRRAFPKHRLMTSGHTSLQRDGTGSFLLDLPNFPDLSKVDINGQNPNIQVTIEVVDGPDSEPENEMQKENMPSWPVPSPDWRSWWQRSATLPRMNYGDQDYKYDSTTEDSNFLNPLGGRNRQVPSHRTFDTKEQPEYDYVDGEGDWSSWSVCSVTCGSGNQKRTRTCGYACTATESRTCDMPNCPGIEDTFRTAATEVSLLAGNEDFNATKLFGVDTDSCERWMNCKSEFLKKYMHKVANDLPSCPCSYPTEVAYSTAEIYDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCFDDSMQLITRGKGAGTPNLISVEFSAELHYKVDILPWIMCKGDWSRYNEVRPPNNGQKCTENPSEDDYLKQFQEAREF
The following text describes a protein:
Function:
May act as a transcriptional regulator of a number of proteins of the circadian clock.
Sequence:
MNGPVPCPTPVDPPAPPPLPPTLEAYAPPPQNQQPEEISPSTSLISGSGLLLARSLLGCRNTSSTPASSSSPCNSRRRWEFTPDEKKDDSYWDKRRKNNEAAKRSREKRRAGDLVLEGRIIALLEENARLRAELLALRFRFGLVRDPCEETRGTYSTQCGLHEPPPANPPPPPPLPHSEDSGFSTPSVGSPVFFEDRVPEHEPQPMPHSALSYYGPINGETVENPRGRLETLGDCYKSLPHKLRFKGGASCEEGLHSIMQVPRETGGFASETAPGFSQQPPPCPRGRWVAHSQEGVPPANSENSELRSQLASLSAEVAHLKRVFSEQVVTRVGHE
The following text describes a protein:
Function:
Transcriptional repressor. May repress NR5A1, PPARG, NR1H3, NR4A2, ESR1 and NR3C1 transcriptional activity.
Subcellular Localization:
Nucleus.
Sequence:
KPWEQVPKKPKRKKRRRRNVNCLKNVVIWYEDHKHRCPYEPHLAELDPTFGLYTTAVWQCEAGHRYFQDLHSPLKPLSDSDPDSDKVGNGLVAGSSDSSSSGSASDSEESPEGQPVKAAAAAAAATPTSPVGSSGLITQEGVHIPFDVHHVESLAEQGTPLCSNPAGSGPEALETVVCVPVPVQVGAGPGALFENVPQEALGEVVASCPMPGMVPGSQVIIIAGPGYDALTAEGIHLNMAAGSGAPGSGLGEEVPCAMMEGVAAYTQTEPEGSQPSTTDATAVAGIETKKEKEDLCLLKKEEKEEPVAPELATTVPESAEPEAEADGEELDGSDMSAIIYEIPKEPEKRRRSKRSRVMDADGLLEMFHCPYEGCSQVYVAFSSFQNHVNLVHRKGKTKVCPHPGCGKKFYLSNHLRRHMIIHSGVREFTCETCGKSFKRKNHLEVHRRTHTGETPLQCEICGYQCRQRASLNWHMKKHTAEVQYNFTCDRCGKRFEKLDSVKFHTLKSHPDHKPT
The following text describes a protein:
Function:
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Synapse. Note=Accumulates at neuromuscular junctions.
Domain:
The PH domain mediated binding to phospholipids with phosphoinositol headgroups. Affinity is highest for phosphatidyl 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
Sequence:
MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLMLVYKDKCERSKGLRERSSLTLEDICGLEPALPYEGLAHTLAIICLSQAVMLGFDSHEAMCAWDTRIRYALGEVHRFHVTVAPGTKLESGPATLHLCNDILVLARDIPPTVMGQWKLSDLRRYGAVPNGFIFEGGTRCGYWAGVFFLSSAEGEQMSFLFDCIVRGISPTKGPFGLRPVLPDPSSGGPSASEERVAQEALEALQLEKRLSLLSHSGRPGSGGDDRSLSSSSSEASHSDISASSRLTAWPEQSSSSAGTSQEGPGLVAAQGPGEAMLGASRPPLKPLRPRQLQEVGRQSSSDSGIATGSHSSYSGSFSSYAGSNLDVWRAGEEFGSLLSLPPGASAPEPRLCACPPGAAEYQVPTSLRHHYDTPRSLRQAPRDPSPASQGSSDHGSATDLGGQAPTGCPSSWLGARRRGQATEGPGSDAALPSPSPGESWEAGSPHAGPPPAFFLSCSICGGLKVKPPP
The following text describes a protein:
Function:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MAGPRQPGQGRQTKQQLQKQQQLQLQQHQLHLQQQPLLQLQQHLFAQQHMRLQQQLQQLQQGQIENESPAGDDNDEEDEEEEDQGDGEEEAEDEDEEAEEADEDEDEEANNDEEDNEVEDGDEDEATTTANDGDEFLSMLEDRKPDQVLMQRNANGSQYSTAHSDKAETDDPLAQLQDLLDDVNSAPLPSTSDSQGTLPSTSAKSTIKGSAANPFMLSGSQFMQSQQYYQLQLQQQQQRLQQSQAKQKQQNLQSSNLHPDLMLLLNKIPADKHDYAKQINEEQFISESSSLISTSSLMNQSSALKGHGDSDLSNSKRHGDNFASTSKRFKHDAKNQASLQQAQAQLYSGNSQKASQQYQPAWMKMNAMTANAAYNSGSRRSISTPGVSMSSVKLQIPTANAPKSKAEVDVTKMDVEGMMDVTSYAGVDLREEEVAMTDTYGAQGQFMALPGLQEPPMLNLSVLDKLIKDFAIKTAGISNIDPAFSRLISQATRVYILNFLHHMRAISQHRSGANFEEFLATERELVSSHITMEVLPIDDVKSEIAVFEEHDRKEEERMMALLGPVVTDAGDGTGEGNDTAYINIAPPVTGNQAATTNDNATNTLLDIKNDKPEGDAAFSTLKSDSASTAIQSTNGSAAVTGEKPSSVGATASTFTPTGASVPVAAQSNSDLKSTAPKEKEKKYKRISKRDMPEAIKNKNINKTALMAAGGALKSWMLPNASASSRSDGIRVASVTTGVSGTISNTGESAGGVGDASDNTARSGIGAATVHRASKRIMLKDALFSLEQKPMLRKSALLYKWLANVK
The following text describes a protein:
Function:
Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSDGIEVEQLVESKPRRMPLATSLEKDSIREAYEDVRSDLTDTEWAVFKFDGAQIIVHARGQCFEEFRQQFGDSERAFGYIRIQMGDEMSKRKKFIFLTWIGQEVGVIQRAKMSTDKALIKDVLNNFAVELQAGVEAELDIELFREALNRAGGANYGTGIRDN
The following text describes a protein:
Function:
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.
Sequence:
MADHLSDIAGHEVTGVFMRTWDELDETGVCTAEGDWRHVQDIAQRLGIPCKRVDFVQEYWHSVFQVMLDELAAGATPNPDILCNRHIKFDAFYHFARDQLGADRVAMGHYARVDEREPDMPRLLRGCDDNKDQSYFLAGLPVHVLRHAAFPLGHLTKDRVKALAAAAGFSDVAGQRESMGLCFVGKRRFGALVQQYLPPRPGVFVHLESGRQLGPVTDLNVITFGQSARLDGQPVRCYVAGKDMTAGAAYVVEGLHHPCLHARAFALSNVHWTHPPPQDVEANLHVRIRHRGQLHPCAVGPLPGPFDSIKGTPAQAEEQFFTDLSLWQVSVVRYVCNRLFQWRRQRRRSLAALAAAITGLWSIFATVMLLLTAFSYFMTWLEQSRDETAQRARHPRDTEDEESLIANEDVSARETVSDQPAAPTYEWDRFMGQVAQSAGETVATAAVASLSQQMSNSAASPAGKGPQPAPGGSASSPATASAAAANKPGLSLGLC
The following text describes a protein:
Function:
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 and/or PEX20 receptors from peroxisomes to the cytosol, thereby promoting PEX5 and PEX20 recycling. The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 and/or PEX20 through the peroxisomal membrane (By similarity). PEX12 also regulates PEX5 and/or PEX20 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10 (By similarity). When PEX5 or PEX20 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5 and/or PEX20, leading to its subsequent degradation (By similarity).
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Domain:
The three subunits of the retrotranslocation channel (PEX2, PEX10 and PEX12) coassemble in the membrane into a channel with an open 10 Angstrom pore. The RING-type zinc-fingers that catalyze PEX5 or PEX20 receptor ubiquitination are positioned above the pore on the cytosolic side of the complex; The RING-type zinc-finger is degenerated and only coordinates one zinc ions, preventing E3 ubiquitin-protein ligase activity.
Sequence:
MDFYSNLDSRSLDSETPTLFEIISAQELEKLLTPSIRYILVHYTQRYPRYLLKVANHFDELNLAIRGFIEFRQLSHWNSTFIDKFYGLKKVRNHQTISTERLQSQVPTLLEQRRRLSKTQIAVSLFEIVGVPYLRDKLDHLYDKLYPKLMMNNLDPKESLKTFVQYYFLKLYPILLSVLTTIQVLLQVLYLSGTFKSPSIIMWLFKMKYARLNSYDYTLDEQRVNKFLNKTSPGKLGTGNNRIRPITLTESLYLLYSDLTRPLKKGLLITGGTLFPASIFLLKFLEWWNSSDFATKMNKPRNPFSDSELPPPINLSKDLLADRKIKKLLKKSQSNDGTCPLCHKQITNPAVIETGYVFCYTCIFKHLTSSELDEETGGRCPITGRRLLGCRINKTTGEWTVDGIRRLMM
The following text describes a protein:
Function:
Transcriptional activator of the arabinanolytic system. Involved in the regulation of extracellular arabinanolytic genes and in the regulation of the intracellular activities of L-arabinose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of L-arabinose.
Subcellular Localization:
Nucleus.
Sequence:
MASSHQGNGTVPNSQTDAPPDSSTKRRWRRNRIACDSCHARRVRCDRQFPCSRCLRSEITCEFTRERRKRGRIARSKLAEMAKNKMETSETPAPAKTMNGIPAPAGTEIPGHVSPASTFHHRSPPANAPTVSAPSVDGRRSQTDPQLPVRRPEIGGNVTEEWLAGTHVSPGSYEFLNGPAFGEGLGPFPHMFDVWNGVDLAAYSAGTSQGSKATNAPSTSTAPLKYPVLQPLMPFVEATLPRKLVFDLLDLYFTSAFSTHMHPVSFLSKDAPRPSSPALLSSMLWVAALDDRAFSLPISPPQRKRICQFLCALTIRLLRPLIHVSFKDQGGAAAAVAAAAAAATNNPAFAGVGQDLPPTTVHHPFEGGGDDRGLVGPAGSLDDVITYIHVASIISSSEQKAASMRWWHAAFTLARELKLNQEIEVMPNGDSQVEGSSPPFGYSLPGWDGADPGPVFNYSNPTRSSLNCVCDRQDQNTITEEHREERRRTWWLLYIMDRHLALCYNRPLALLDAESEDLLLPLDEASWQSGIIHSNSPKSDGPQCLLSADKNKRRLFPNFICHDHSVFGFFLPLMTITGELIDLNQARNHPMLGMRLNGKDAWNVHVSEVLRQLEIYKASLTTFAATTSDPEAPLSAYAHAQSEHLPAEPSLSQAYAWHTQTVISYASYLVHVLHILLVGKWDPVSLIEDKDFWTSSPAFASTISHALDAADSVDQILRYDPDISFMPYFFGIQLLQGSFLLLLIVERLQKEAGEGILNACEVMIRATESCVVTLNTEYQRNFRQVMRSAVAQARGRPVNHSEIRHRRKAVLALYRWTRKGTGLAL
The following text describes a protein:
Function:
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Sequence:
MSNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHVAKGLQLTCTTTSRATSEVARDVGIELSDPNEMNEIDLTIDGPDEIDRRFNMIKGGGACLLWEKIIAHASKRMICICDETKIVNCLGQFPLPVEIVPFAWKQTERRVERVLAEQGLHHVPIIRRMGGGHPVITDSGNFILDCHCGAIITAPEPLEIELNRIPGVVENGLFTREATGMVVGYFDGSSYVQLR
The following text describes a protein:
Function:
Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X-X-S/T-C2 of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS superfamily and the thrombospondin (TSP) and spondin families (By similarity).
Subcellular Localization:
Endoplasmic reticulum. Golgi apparatus. Note=Mainly located in the endoplasmic reticulum.
Sequence:
MHFFPIQLLVLFFAEKIAFAENSDQTVSRVDSNRYSVAAEKKFLLYDVNFGEGFNLRRDVYMRVANTVRSLRDSGENYILVLPPWGRLHHWKRMEVALSWRLFFDLESLNRFIPVIEFEDFLDENRPIDQVIYLQHYAEGWGTEYVRKFEKRSCLPPAESHYKQVEEFKWKGWFYSYEDVYSRNFQCVSIQGDSGTLKDLLKHSNFSESTSIMVDRAETILHEHYGEVDYWKARRSMRYSNDLVDVADAFRKKYLDSDDKRDKTKLVDDWTKEKPRRTAIGGPYLGIHWRRRDFLYARRAQLPTIPGTAKILQDLCKKLDLQKIYLATDAPDQEVDELKALLNGELEVYRFTDTQKLNDGQIAIIDQYLCAHAAYFIGSYESTFTFRIQEDREIIGFPISTTFNRLCPDTEPTCEQPAKWKIVY
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MQGSPRQPSSAGEPTAAPLASSNSAGHGDRAQQPRQQPEGAHTAVPMPPEPPVPPFGVSRSQLFALNDAKDTDGLRALGGAPRLARLLLCDLKEGINGADADEEDRHGSGRHASSSLGKHAAKQGGAAADGVSGGVTMPAPSIAERVKVYGANEMAAVPPKSLLALIWDNLQDPILLLLIAAALVSTVLGAAIPEERHESGWVEGVAIWVAIAVVVLVSSFNDYSKDRQFAALNRQRDVIEVTVVRGGAEVRVHNTQVVVGDLLVVCAGDKVAADGVLAVPGLDRGGLLAADESSLTGESEPVKKSVEEDPWVRCGTQVQEGGGRVLVLAVGGDTEYGRTLAIVGSAGGQDTPLTEKLGHLASAIGKIGGAAAVVLFIVLMVIWMVRNRGFPIKKINDRGPVQFFLYCVTLVVVAVPEGLPLAVTISLAYSMRQMMDDQCFVRVLEACETMGGCTAICSDKTGTLTQNRMTVVEGWIAPGTKFSRAPRAAEVPRPLLDDLRRGIALNSRAFLVEPAAAARGGGGGAKRNQTPGKKSPPPHPPAPAAAVAAPRLSQPPSLNTAAPSRASSTSASVAAASRMTLAGSSVAGGGDSSATAAAVAAAPYGVDGVTGLEAAAAGDQELGLEDVSNKSSGSRSRRKAFGGTNNAAAGRMRSYHRGGGGDGGGAKGAAAWHERAPASWLLLRPCWRALAHLCVGIVHCLPPHAAGAAGFGGRTASAVSDDGEASEHDGADGAIADGGGGGGGAGVGELLYGGGGGGGGAVVVPPRIQMVGNRTECALLLLMDYAWRQQQPQQPPPPPPQQQQQQQPPHPQQQQQQQQQQQQQQQQQQQQQQQQQQQPPHPQQPQQQHQLDGVTAAADSHAATAAAVAPAPAAAGGGDEPQTYDALRRLYEGGGRLEHVYGFTSESKMSSVAVRLPDGRLRLYTKGAAEWVLRQCTSVQTSDGRGTQPLDEVARQLLTRQVVDDMAARGLRCIGLAARDVPEPAGGAGGGGWPEGYWEEAPVEDMTLQALLGIKDPVRPEVPAAVATCQRAGITVRMVTGDNINTARFIARECGILTDTAGSDAGGADGGGGGGGGGLALEGPAFRALSDAQLDAALPRLQVLARSSPSDKHRLVRALRAQREVVAVTGDGTNDAPALKESDVGLAMGITGTEVAKEAADIVVLDDNFSSIVRAVLWGRTVFENIRKFVAFQLTVNIVALVVAFVGAIAGGHQPLTVLQLLWVNLIMDTLAALALATERPDPQILDRAPYGRRESLITGVMLRYMLSQAAYQIAVLFFMLYAVPVVLPARYGEAVDPNHTRSLSLLFNTFILCQVFNEINSRRISDELNVFARLHRSPIFLAVLAVTVGAQVIIMELLGSFFDVKPLDWREWLVSVALGAVSLPLSTLVRLAGRSWDRRHRPQSGRGAAAAAGAAMERRSSGADGEGGAAGRGGGGGGPGSGGGGKGVGAEVEEQEQEQHLAVRPTVAPEPAGSRADC
The following text describes a protein:
Function:
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
Subcellular Localization:
Preautophagosomal structure membrane; Peripheral membrane protein.
Sequence:
MSRIIHSEDDDDDDVGSQSSSSLSSPSKSLQQDPIPTKIPLSTSIILEKKLPLEQHQKLSNLTEGSTAGGHVSNNSLDNKIMIRFVPIGSTPSIQPRVFKISATQTVSTLNRFLCKKLKFKGVLNLYIQNSFMPLPDEQIGSLYGLFKTNNELIISYCNTIAFG
The following text describes a protein:
Function:
Inner membrane hub protein that plays both cAMP-dependent and cAMP-independent roles in twitching motility. Regulates intracellular cyclic AMP (cAMP) levels through the activation of adenylate cyclase CyaB. Plays an essential role in a number of virulence mechanisms including type IV pilus (T4P)-mediated assembly and twitching motility as well as cAMP-dependent virulence gene expression. Also mediates type II secretion (T2S) of lipases and proteases. In addition, mediates the cAMP-independent localization of multiple T4P structural and regulatory components to the cell poles. This role in directing proteins to the cell pole is not restricted to type IV component and involves other proteins such as the diguanylate cyclase DgcP (By similarity).
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Domain:
The N-terminal domain binds peptidoglycans through LysM motif. In addition, this motif is required for PilQ stability and multimerization. The cytoplasmic domain contains three discontinuous tetratricopeptide repeat (TPR) motifs involved in protein-protein interactions.
Sequence:
MVRLRTLVRAIAAASVLTSGMAHGLGLGEITLKSALNQPLDAEIELLEVRDLGSGEVIPSLASPEEFSKAGVDRLYYLTDLKFTPVVKPNGKSVIRVTSSKPVQEPYLNFLVQVLWPNGRLLREYTVLLDPPLYSPQAAASAPQAPVSAPRATGAPRAPQAPAPVRTTAPAGSDTYRTVSNDTLWEIAQRNRTDRVSVPQAMLAFQELNPGAFVDGNINRLKSGQVLRIPTEQQMLERSPREALSQVQAQNQSWRGSRNPAAGSAGARQLDATQRNAAGSAPSKVDATDNLRLVSGEGKASKGADKGGKGDSKAIADTLAVTKESLDSTRRENEELQSRMQDLQSQLDKLQKLIQLKDAQLAKLQGQLGAEGQGAAQPNAALPDASQPNAAAQAPAQPGTPAAAAPTPAPAGEAPAAPAQPPVAPPPAPAAEKPPAPAVPAPAPVQAAEQPAPSFLDELLANPLWLAVIGGSALLALLVLLMILSRRNAQKEKEEAQAFAADTGEEQEDALDLGKDGFDDLTLDEPEPQVAAVAPQVEKTTAQTSDALGEADIYIAYGRFNQAAELLQNAIYDEPQRTDLRLKLMEVYAEMGDREGFARQENELREIGGAQPQVEQLKSRYPAMVAVAAVAGLAGAKLAQDELDSFSLDDLSLDDSGHAAKPDAAGQDLDDAFDLSLDDLGGDDVQADLKSDSGALDDLTLDSDLDLAASTPADKPVDDLDFGLDFAELAETPSQPKHDDLGDFSLDLDAPEDKLSDDDFLLSLNDEVPAAAPADNEFTLDTEAAEEPALSLPDDFDLSLADEPTEPAAPEKGEDSFAAQLDEVSAQLDELASNLDEPKSATPSFSAEDAAVASALDGDADDDFDFLSGADEAATKLDLARAYIDMGDSEGARDILDEVLAEGNDSQQAEARELLERLA
The following text describes a protein:
Function:
Through its association with the EHMT1-EHMT2/G9A and PRC2/EED-EZH2 histone methyltransferase complexes may function in gene silencing, regulating repressive post-translational methylation of histone tails at promoters of target genes.
Subcellular Localization:
Nucleus.
Sequence:
MPMKGHVEGLAARSSYFLDWDFDMHFFLEMQIKKMKEMVPPLYAQQTNDANDSSSTSPKQPKSEKGKQPNGQEAQSLCYQGNEAEGGRVSAVTCGKCGSVHQIPTTDSKKQNQRSPSADQKLFVCNQCSLRVPPPFHFVSDTAGAVDVGSTEKSIPRKNENKFQVRNFQPGKYYCDKCRFSTKDPLQYKKHMIQHEEIQFICSHCNHISYTKGEFQRHLVKHTGTFPYKCEYCSYGAIRNDYIVKHTRRVHETVNHKRQIKPNGGPARKRAAWPPGDKGLLGAQNGPNTKGRFNSPSSAGPFREGQVGVGGRADPREPGKETAAVPERVGVLDSTGETLFEDRNVEVEVVSPVKEPVLPGMPLTVVAPAELVVPANCLAQLLDIKTVNGTQQLILKLIPLREKNLFKPACGPAPERSNFPSSQAVSEQGKSAPAAPTKPPSPTGRVREPADGGDGKHKGSERLGSSYPCPSGWSSANTQGRGEPCPGRDPGVALTRETISESGRPDRFPVSLLPLDGDGSSVTPKLSKGINGDSCRTQRKAAVLPVHSAAFHREDGKRAGDQPTRPADEGPSTAAGSHLGASPSGQGGSGSGTGAGSLCKIPPSHLPLETSVVGRDSHLSELALAPNGLTPVSSDVSQTLETTPGDSLELDISTGHPRSPEGPVISSVFSLSTGEENVPEGIKWGDPTHKSKSAALLCEKIARLISASESAARPSFCLPAAKQQHSVPAELLKGRSLEGLDVPGPGTDSPSPPETQNGGEAGEQFVHVAVGPPGDEGDRKINFRGMKKAHIATPVFIPEGTVLRVLNCGEKAHEVESESQEPLKPYCNETLLPRPVPLSALEKPGPDFPSLLGDVESTDRPRNLRAFARSKAAREATPHSPTSKQTPTPPHPPKGSNPNKPSRPAAKGSPTPRCKSKPGNQSRKKAKGQLSGERPHVVVARQLRLAPAKVGQLIKCPRRNQPVIVLNHPDVDPPEVINVMKIINKYKGNVLKVVLSERTSHQLGIRRNHRRLTCRNLETASPVKKQIMLKMKLKKIHKNNYQEMHHLKEES
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MERKKLIAKFVEIASEKMGKDLETVDEENTFKELGFDSIDVIDLVMFFEDEFALRIEDEEISKIRKVKDLIDIVIKKLEEIDDEVSEG
The following text describes a protein:
Function:
Involved in resistance against the herbivorous insect brown planthopper (N.lugens, BPH). Member of the BPH3 (BPH resistance locus 3) cluster which contains LECRK1, LECRK2 and LECRK3.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MCRSIIVPISSSSKCNSTGCAVDMNRVCPTELKTIQNGQVVGCQNPCGRRSQERYFCCIGGDARSNCKPSVYYSKIFKTSCPQAYSHPKGDQTSMFSCYDPVDYNIVFCPTSSNSRSVGDSLMAGNGTSRWLSPSGDFAFGFYQLPNEFFLLAVWYDKMPNKTIIWFANGDNPAPIGSRLELNDSGLVLNNPQGLELWRSNFASGTIFNGLMNDDGNFQLLDQNAVSLWETFTHPTDTLVPNQVMELNGKLFSRRGEFNFSHGRFKLHLQEDVNLVLSLINLPSNYSYEPYYDTGTADANNQTNIGMKLIFDKSGFLYILKKSGEKFYITKPNETISTNDFYYKATINYDGVFTVSYYPKDLRKGQGWVTTKTIPENICLSSTFTDGEGVCGFNSICNLKADQRPICNCPERYSLIDSNNMYGGCVPNFQVVCQGGGYMVSQDDYIMKELRNTDWPTSDYETLSPYSLKECTKSCLQDCLCVLVTFSGSSCWKKKLPLTNGRRDKGVNATSVIKLMKNDYLLTSFPNPNGKKDHDVLIVVLSVLLAGSVLIILMLVGALYFGFSCNRKKIESSRTNKSVAKKNLHDFTFKELVEATNNFREELGRGSFSIVYKGTIEMTSVAVKKLDKLFQDNDREFQTEVNVIGQTHHRNLVRLLGYCNEGQHRILVYEFMSNGTLASFLFSSLKSNWGQRFDIALGIARGLVYLHEECCTQIIHCDIKPQNILLDDQYNARISDFGLAKLLLINQSRTETGIRGTKGYVAPDWFRSAPITAKVDTYSFGVLLLEIICCRKNVEKELVNEEKGILTDWAYDCYKTRRLEILLENDDEAINDIKSFEKLVMIAIWCIQEHPSLRPTMKKVLLMLEGNVEVLTPPSPYLHGSISEN
The following text describes a protein:
Function:
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
Sequence:
MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNAQAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPFAVRYEARPGTGAIVTELPEKKWKDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGSPYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQDFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDLGKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYYFLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEEDPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNLYTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDHRCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPVAGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRLKSTKTVTNKNPKGVENEK
The following text describes a protein:
Function:
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co-regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB, YAB1/FIL and YAB3, and through positive regulation of LOB domain-containing genes LOB, LBD6/AS2 and LBD36. Promotes and maintains a developmentally determinate state in leaf cells through the negative regulation of JAG, JGL and class I KNOX genes. Is also involved in nectary development, formation of normal abscission zones (AZs) and suppression of bract formation, probably by regulating the cell wall disorganization.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSLEESLRSMSLDFLNLLINGQAFSDVTFSVEGRLVHAHRCILAARSLFFRKFFCGTDQPQSCIDPTRHGSVPASPTRGSQAPAGVIPANSVGYEVFLLLLQFLYSGQVSIVPQKHEPRPNCGERGCWHTHCSAAVDLALDTLAASRYFGVEQLALLTQKQLASMVEKASIEDVMKVLIASRKQDMQQLWSTCSHLVAKSGLPPEILAKHLTIDVVAKIEEIRLKTSISRRSLMPHNHHHDLTVAQDLEDQKIRRMRRALDSSDVELVKLMVMGEGLNLDESLALHYAVESCSREVVKVLLELGAADVNSPVCPAGKTPLHIAAEMVSPDMVAVFLDHHADPNVRTVGGITPLDILRTLTSDFLFKGAVPGLTHIEPNKLRLCLELVQSAAMVISREEGNNSNNNNNDYNNPSYPQMNEEHNSGSSGGSNNNLDSRLVYLNLGAGTGQMGQGRDHGDDQNSQREGMSRHNHHHHHDPSTMYHQHHF
The following text describes a protein:
Function:
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Sequence:
MACCGEDEGACASTSSKDRGQRKKKQPEGKSKVGEKSRLLGCTHPPTLSMVVEALRANREKQGTSVAAIKSYILLKYPAVDQIRLKYLLKLALAKGIDHGILVRPPNSTAKGATGRFKLGPKGQTKKTSMGTKPQKKIPKPDKTVAKSKTKEATPKAESKDTKDVKVKPKAKKPKAKSTNDQSKAAATKSSEGKVGKKTKHKDAIGVKATRVKTTEKKNSRKEAKAVVGEKEPVGQKKASLPPKAKKAKGVSITVQKPKGTKGAEGKGITKVKAVPETSGTPGTKIRPVSGSKTSVASKPKELTAPNGLPKDKRKKTEATKGPRKAGPNSKGPLTKNSSKPAK
The following text describes a protein:
Function:
May play a role in cilium biogenesis.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.
Sequence:
MSVSRVTMMRKGHSGEVARKPNTVVVSVPPLVKKSSKSRSFHFRYLELCRAKNLTPVPEIRSKSNATTTFLELCGDKLAVSDWQLLTEALHYDLVLQQLVVRLRRTYPQTNIDPIDTEKRARLFRQRPVIYTRFIFNSLVQAIANCVSSNKNLSVLKLEGLPLQDGYIETIAKALADNECLESVSFRKSNIGDKGCEVVCNTAKYLNRIEVFDLSECGLTSKGAEHVADMLKMQKITRFTEGWEKSLRYRSVDVNTIGGLRTVLLADNPEIGDVGIRWITEVLKEDAWIKKIDMEGCGLTDIGANLILDCLELNTAITEFNVRNNEGISKFLQRSIHDRLGCLPEEKQEPEYDLSCVNGLQSLPKNKKVTVSQLLSHTKALEEQLSFERTLRKKAEKLNEKLSHQLMRPDSNHMVQEKAMEGGSQTNISREYVARNDVMPEVIKNSQSYRQSHFNRLVNSAATSPEVTPRSEIVTLRKEQQLQRQQPPPMEVKHLSLEQQIRNLRDVQKKVDLDVEEEEEEEEEEQQAEESQSESEPQNEEQQHYEQQMQVQRKHLQVRKVRSEIKYVENNPKEAAKKNRESKSDHEFANERDFKLNPSVQFETDIGDNVMVNPGHRYEGGGGDTAYVYNYEHEQQQQPVKRGYEHGYVVGVGDGSHRRQRQSQLVEALVQKRVPGASDGHVAQFVSNLERQANAGKTGKKRLKPRPEDDLQVPVGDMHMESSYMSRSEELSSTDVTLENSDYETEATDSTLLSSSKYSSMHVFVRRKQSESMSLTEEAGDGDAGGGGGSGDFGDQNVISPANVYMSLQLQKQREQSA
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. Functions in the N-end rule pathway of protein degradation, where it specifically recognizes and ubiquitinates proteins with a N-terminal bulky aromatic amino acid (Phe). Does not act on aliphatic hydrophobic and basic N-terminal residues (Arg or Leu) containing proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MAETMKDITMKNDESQEEEIPDQFLCCVCLELLYKPIVLSCGHLSCFWCVHKSMNGFRESHCPICRDPYVHFPSVCQKLYFLLKKMYPLAHKKREEQVLKEEQERECFSPQIDLVLDLSVCSGDSLNVSDKQKVEECSNAANLLSSSSSRGDIPCIPKNQEPTDAKALNVHENELLKDNKVSKQISKDDLLCSACKELLVRPVVLNCGHVYCEGCVVDMAEESEKIKCQECNVCDPRGFPKVCLILEQLLEENFPEEYNSRSSKVQKTLAHNSKGNIQSYLKEGPSLSNDNNNDDPWLANPGSNVHFGAGCDSCGVYPIIGDRYRCKDCKEEIGYDLCKDCYETPSKVPGRFNQQHTPDHRLELARSPQVLINFNSIGILLGPVISNEGMDTDEGEEGPPGSSNESSSTE