lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Anchors the lamina and the heterochromatin to the inner nuclear membrane.
Subcellular Localization:
Nucleus inner membrane; Multi-pass membrane protein; Nucleoplasmic side.
Sequence:
MQHSPSTTTDHIHFAARFFDRNSYTMDRRLRRPRRTEDVSSGPLLAQSKQPSLLPVTRRTGSVTAAGATATATATAGPATRTRASPSRNKVVAPPSPDLGPRTRRSSRPRSSVGPLTGSGSGSSLPIKAAIKARTPIPEVSEVSSPIRLSTSNLPMTLTTNTSSGAPNKAFNTSSVNSGNSFSRTTTSSTTTTTERIEIRAEGDGEVDTDSIRKRITERLRRSVSKTISNLAGTPVTNTEEGSRYSRSVSRSVYDDEKSSKRSYSTGEEDIDEEDELEEDQFRSFNVTRKSATPAEISCRQLKAPREFGGWLGAFLFLLLLPTAVYYLTWSCTARNACQFKHLNLGILLDVNYLTRQVFQPRVVGAFAAYQVVVFLLVALLPGRRVHLTRETYKFNCLAVSLTLLIASGVAEYLKYPVVTFVLRHYLRFCIFGLVGAFVAAAWSYWLVDTAKYNVLRQTLTNDYGRTGSFVVDFALGRQLNPKWLGRVDWKQFQYRLSLVTTLIYATCYIYQTLVWPQKPQLGEQEGYLYQAKYYWNNVNYDPATLFSASCLLFYVLDAIIFEHHLSSSFELQHEGYGCLLLLRYAATPYLLTAVTKYFYEQRVPISCWYAPLAVAALLSLGLLVKRFSCAYKYKYRLNSQSPIFANIETIHTYQGSRLLLSGMWGWVRQPNYLGDIVALLALAAPMALRPAWPPVLGLSLIILLLLHRATRANARNQARYHSSWQRYSTQVRSYILPRVY
The following text describes a protein:
Function:
Damages membranes of susceptible bacteria. Has no hemolytic activity. Not toxic to mice. Does not inhibit the proteinases elastase and cathepsin G.
Subcellular Localization:
Secreted.
Sequence:
MSSGGLLLLLGLLTLWAEVTPISGQDRPKKPGLCPPRPQKPCVKECKNDWSCPGQQKCCNYGCIDECRDPIFVN
The following text describes a protein:
Function:
Major protein of the otoconia, a calcium carbonate structure in the saccule and utricle of the ear. Together with OTOL1, acts as a scaffold for otoconia biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure. Together with OTOL1, modulates calcite crystal morphology and growth kinetics. It is unlikely that this protein has phospholipase A2 activity.
Subcellular Localization:
Secreted.
Sequence:
MIGILLMSMFMVLHSVGGQELEPPAFLPELLNTPERILNNATFFNGVFQNVESVALFFDCLGSHFTWLQSIFTNFPALLNFVNKMKCVSGFCPRDFEDYGCSCRFEMEGLPVDEADECCFQHRKCYEEAMEMECTWDPSKISTDVTCSAENLSCENGDPCEQFLCTCDKDAIECFGNAHINSSLNGLDVSSCPSLVTETTSKRELTTRHTGEFFHRETEKAEAVTASVEEAVISSEPSEMALGTSSAGGKNPDILLLVNQALLTPEDRFTGAEVPAGEITTSPGSFQADINSAEVRIIPTEFIPVGTSARTKEKEAIPTRGGLGTPSPRAALEELSLSVRGPNGPAGKVCERLTFLQERGNGREKRELPQLGEMLFCLTERCPEEFESYGCYCGQEGRGHPTDALDRCCFSHHCCVEQVKTLGCPAERSSRSEVVCFDHMPKCIGWSLCEKLLCACDQTAAQCMASALFNESLKFPHGQVCQEEKASCRGGPYERPSVGTEPGAQTSSSEESSEEEGFLRRRARRETRRPPGKPRSGQHRGR
The following text describes a protein:
Function:
Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis.
Sequence:
MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIVSCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFNRD
The following text describes a protein:
Function:
Catalyzes the hydration of acetylene to form acetaldehyde. Ethylene cannot act as a substrate.
Miscellaneous:
MISCELLANEOUS: The tungsten center binds a water molecule that is activated by Asp-13 residue, enabling it to attack acetylene bound in a distinct hydrophobic pocket.
Sequence:
MASKKHVVCQSCDINCVVEAEVKADGKIQTKSISEPHPTTPPNSICMKSVNADTIRTHKDRVLYPLKNVGSKRGEQRWERISWDQALDEIAEKLKKIIAKYGPESLGVSQTEINQQSEYGTLRRFMNLLGSPNWTSAMYMCIGNTAGVHRVTHGSYSFASFADSNCLLFIGKNLSNHNWVSQFNDLKAALKRGCKLIVLDPRRTKVAEMADIWLPLRYGTDAALFLGMINVIINEQLYDKEFVENWCVGFEELKERVQEYPLDKVAEITGCDAGEIRKAAVMFATESPASIPWAVSTDMQKNSCSAIRAQCILRAIVGSFVNGAEILGAPHSDLVPISKIQMHEALPEEKKKLQLGTETYPFLTYTGMSALEEPSERVYGVKYFHNMGAFMANPTALFTAMATEKPYPVKAFFALASNALMGYANQQNALKGLMNQDLVVCYDQFMTPTAQLADYVLPGDHWLERPVVQPNWEGIPFGNTSQQVVEPAGEAKDEYYFIRELAVRMGLEEHFPWKDRLELINYRISPTGMEWEEYQKQYTYMSKLPDYFGPEGVGVATPSGKVELYSSVFEKLGYDPLPYYHEPLQTEISDPELAKEYPLILFAGLREDSNFQSCYHQPGILRDAEPDPVALLHPKTAQSLGLPSGEWIWVETTHGRLKLLLKHDGAQPEGTIRIPHGRWCPEQEGGPETGFSGAMLHNDAMVLSDDDWNLDPEQGLPNLRGGILAKAYKC
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MINRKPTRIELNMEDIEEYEQLKKEQTNSYKQQQQQQQPTTISTPKQYPLLNTTQPPKKTTAQIIGYDQ
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MSSFDSLQSVEQRVIRVVNIAATVMEEMSSTSGPRQDRVTSLCSEFMSEIKEIQSRLREEIKNMTEYKPFENCDYVSQAKSTISAEKVSNLQRQLEELQKDVGRREPDANLPLEVVPLRTEISNGNHSLPMEPGGRESR
The following text describes a protein:
Function:
Putative transcriptional regulator for the sgcREAQCX region.
Sequence:
MSQQRPDRIKQMLHYLWQHRHLSTQQAMELFGYAEATVRRDFQYIVNQYPGMIRGHGCLDFDDSTDDKEYVFDVKRTLQSVAKREIAALARTMIKDGDCFFLDSGSTCLELAKCLADARVKVICNDIKIANELGCFPHVESYIIGGLIRPGYFSVGESLALEMINAFSVERAFISCDALSLETGITNATMFEVGVKTRIIQRSREVILMADHSKFDAVEPHAVATLSCIKTIISDSGLPETIAQRYQRAGCQLFLPHSIK
The following text describes a protein:
Function:
Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
Sequence:
MPRFPDQLLYIGGRYVPARGGHTFEVVNPATGEVLANVHNADADDLDAAVDSAKAGQRHWAALTVVERSRILLRAVALLRERNDALAELETLNTGKPLSETRSVDIVTGADVLEYYAGVAQALQGVQVPLREGSFFYTRHEPLGVVGAIGAWNYPIQIALWKAAPALAAGNAMIFKPSEVTPLTALKLAEIFTEAGLPDGVFNVLPGDGASVGHALTEHPEIEKISFTGGTATGRKVMASASSSSLKDVTMELGGKSPLIVCADADLDLAADIAMMANFYSSGQVCTNGTRVFVPRALRTAFEARLLARVQRIHIGDPLDERTTFGPMVSAAHMQRVLEHIEQGKAEGARLLFGGERLRDGALAQGCYVAPTIFSDCTDVMTIVREEIFGPVLSLLTYDDEDEAITRANATSYGLAAGVVTPDLSRAHRLIHRLEAGICWINTWGESPAPMPVGGYKQSGVGRENGLATLQAYTRTKSVQVELERYASVF
The following text describes a protein:
Function:
Probable tRNA acetyltransferase required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs. Binds RNA.
Miscellaneous:
MISCELLANEOUS: Present with 2630 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGEKRNRNGKDANSQNRKKFKVSSGFLDPGTSGIYATCSRRHERQAAQELQLLFEEKFQELYGDIKEGEDESENDEKKDLSIEDQIKKELQELKGEETGKDLSSGETKKKDPLAFIDLNCECVTFCKTRKPIVPEEFVLSIMKDLADPKNMVKRTRYVQKLTPITYSCNAKMEQLIKLANLVIGPHFHDPSNVKKNYKFAVEVTRRNFNTIERMDIINQVVKLVNKEGSEFNHTVDLKNYDKLILVECFKSNIGMCVVDGDYKTKYRKYNVQQLYESKFRKDEDKSVKQ
The following text describes a protein:
Function:
Cell wall formation.
Subcellular Localization:
Cytoplasm.
Sequence:
MVAVTAFDTSQLSTFRTHHHFERYGEFKSAEEFAEYCRWADGHSARVYILGNGSNTLFARPSVRSLVLKNSLPRTIRSLGDGRVEVSSTVQINEVLNYCYQHALDSFYYLASVPASIGGALAMNAGRGKTHHCTIYDFVESVTYVHEGAVQTLSNAEIQRGYRRTMFTGIQRSLILSAVLRFDAAHFEHNPLTERRQWAKEHQDNTLPNCGTVFKYASYPIMNRLRGLRIGDAYFSSKTSNWILNKSSSSAPILTLIKVAKVLHYLSFKKIDLEVIEVD
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Sequence:
MANSRQYYPSQDESMSPTSVRSREWEGPSRWTEYLGPEMAASVSSTRSSKQIDGHVGGSTKALNIQWVVQMIEVADGLMAKMYRLNQILEYPDPVGHVFSEAFWKAGVFPNHPRICTLLSKKFPEHFSKLQLERIDKFSLDSLHDGAELHLQSLEPWIQLLLDLMAFREQALRLILDLSSTVITLLPHQNSLILHAFMDLFCAFVRVNLFAEKIPRKMLLQVYNLLHALSRNDRDCDFYHRLVQFIDSYDPPLKGLQEDLNFVSPRIGEVLEAVGPSIFLSADTRKLRNEGFLSPYHPRFPDILTNSAHPMRAQDLANVTSYREWVLLGYLVCPDELLRVTSIDIALVVLKENLVVTLFRDEVSLYQMVCEKEFGIGISFASADSINLTMQYILLHEDYQLYVLPRVLESKKMAKSGRTKQKEADLEYSVAKQVEKMISEVHEQALQLCDTIHRERRILLKQEIGRMVLFFTDQPSLLAPNIQMVFSALALAQSEVLWYFQHAGIASSRSKAARVIPVDIDPNDPTIGFLLDGMDRLCCLVRKYISAARGYALSYLSSSAGRIRYLMGTPGIVALDLDPTLKGLFQRIVQHLESIPKAQGENVSAITCDLSDFRKDWLSILMIVTSSRSSINIRHLEKATVSTGKEGLLSEGNAAYNWSRCVDELESQLSKHGSLKKLYFYHQHLTTVFRNTMFGPEGRPQHCCAWLSVASSFPECASLIIPEEVTKFGRDAVLYVESLIESIMGGLEGLINILDSEGGFGALESQLLPEQAAAYLNNASRISAPSVKSPRVVGGFTLPGHESYPENNKSIKMLEAAIQRLTNLCSILNDMEPICVINHVFVLREYMRECILGNFKRRFLTALQTDNDLQRPSVLESLIRRHMGIVHLAEQHVSMDLTQGIREILLTEAFSGPVSSLHTFEKPAEQQQTTGSAVEVVCNWYMDNIIKDVSGAGILFAPRHKYFKSTRPVGGYFAESVTDLKELQAFVRIFGGYGVDRLDRMMKVHTAALVNCIETSLRSNRELIEAAAASMHSGDRVERDASVRQIVDLDTVIGFCIEAGQALAFDDLLAEASGAVLEDNASLIHSMISGIVEHIPEEIPEKKEIRRIKGVANGVGVAGDHDSEWVRLILEEVGGANDNSWSLLPYFFASFMTSNAWNTTGFNIETGGFSNNIHCLARCISAVIAGSEYVRLQREYQQQHQSLSNGHHSSENLDSEFPPRVTAEASIKSSMLLFVKFAASIVLDSWSEANRSHLVAKLIFLDQLCEISPYLPRSSLESHVPYTILRSIYTQYYSNTPSTPLSTASPYHSPSVSLIHASPSMKNSTTPQRGSGSGSSSTAAPDSGYFKGSSSSLYGQEHYTESETGNSRNNENNNNNKQRGSSRRSGPLDYSSSHKGGSGSNSTGPSPLPRFAVSRSGPISYKQHN
The following text describes a protein:
Function:
Interferon-stimulated protein that plays an important role in innate immune response against a wide variety of viruses. Inhibits flavivirus replication by preventing the formation of virus-induced endoplasmic reticulum membrane invaginations, which are double-membrane vesicles that flaviviruses use for their replication. Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis. However, it has also been shown to have a pro-apoptotic activity. Modulates innate immune response mediated by RIGI by preventing its activation.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MRQKAVSLFLCYLLLYTCGCCEEEDEKRYSEENSDSSFWGMVTYMAVGGGLMAAALPMLGFASTGIAANSLASSLMSWSAVANGGGVPAGGLVATLQSLGASGGSALMAKIGAFLGYTVHKQVESRQKESKEKK
The following text describes a protein:
Function:
Protein-lysine N-methyltransferase. Monomethylates PRMT5, modulating its transcriptional activity. May also act as a histone methyltransferase. Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDLPVEKWQMHVRQKWSSLEPSLKEKLSRPSSLRAAFLLSSSLLQPEDEEYLLSLSKDFSVNKDPSLVLSCKEDGNTRFRRKEYKSAAALYSKALSHAEIGSPEMAICYANRSAALFHLGQFEVCLADIGRAQEGGYPEKLSPKLFLRRAECLQKVSQLEGERVPETDAEAWEENGLISCASPSMRLAFSKDKGRHCIAQTDIVPGEILLKEEAFVAVLCPGEEDIHCHHCLSPLVASVPCRGCSYAKYCGSACARAAWQSYHQRECPFGGLLLAMGVFCHVALRTIFVAGFEEVTLFVENDEEQTTGISIPGCDADGRYRSSYQAVFGLLPHVEKHSPEFKFLCGFSVAALCRVMGKELFVGKDGENVAQDVLGEAVLRHVLQLQCNAQAVTALRVSGCEAVARQEEVTLATALFPVLSLLNHSCDPNTSVTFDGRTATARASRAIPRGQEILHCYGPHRCRMKPSERRQRLLAQYFFECRCSACTDETGPESASGSTLFCCPTCRAPMQGEGLFLCCSSASCKAMLPKEGFQHQLRELRQHMEAAMDLLAQGKADRSVEQLRKCHLEAQQLLSPGHLVVGEIEDHLAQVHATQGNWPEAAAHLRRSIEVVEAHYGAGSIEVGQELFKLAQVLFNGRFVPEALQAAEKAEAVLSVQLGPRGPEVQELQEMKACLEKLLQG
The following text describes a protein:
Function:
RNA-binding protein required for assembly of the holoenzyme telomerase ribonucleoprotein (RNP) complex. Specifically binds telomerase RNA and promotes its assembly with catalytic subunit p123, thereby stimulating enzymatic activity and processivity of p123. Telomerase is a ribonucleoprotein enzyme essential that copies new telomeric repeats onto chromosome ends and functions to maintain cell division.
Subcellular Localization:
Nucleus. Chromosome, telomere. Note=Localizes to the macronucleus.
Sequence:
MEMDIDLDDIENLLPNTFNKYSSSCSDKKGCKTLKSGSKSPSLTIPKLQKQLEFYFSDANLYNDSFLRKLVLKSGEQRVEIETLLMFKKIRSLLKEHYGENYLILKANNDEYIKFICECVKGSRYIRLTKDKLAIKRKKKFDNRTAEELIAFTIRIDGELPSLETIEKAVYNCRNRSSESSDVNKPNKPCKFNGIYVKSFGTNAHCIYIGFLKHRYTECFRDCFSLQQITCFDYSCSSLISLKEAGEMKRRLKKEISKFVDSSVTGINNKNISNEKEEELSQSCFLKISKIPAGSKKYQIREALDCDRPSYIQYDDKETAVIRFKNSAMRTKFLESRNGAEILIKKNCVDIAKESNSKSFVNKYYQSCLIEEIDEATAQKIIKEIKDQRSSIDEIKAELKLDNKKYKPWSKYCGRKRRPVSKRKNKAINKMSTEVKK
The following text describes a protein:
Function:
Acts as a component of the SAGA (aka STAGA) transcription coactivator-HAT complex. Mediates the interaction of SAGA complex with the CRX and is involved in CRX-dependent gene activation. Probably involved in tethering the deubiquitination module within the SAGA complex. Necessary for microtubule cytoskeleton stabilization. Involved in neurodegeneration.
Subcellular Localization:
[Isoform a]: Nucleus. Nucleus, nucleolus. Nucleus matrix. Cytoplasm, cytoskeleton. Note=In addition to a diffuse distribution throughout the nucleus, it is associated with the nuclear matrix and the nucleolus. It is able to shuttle between the nucleus and cytoplasm; [Isoform b]: Cytoplasm.
Sequence:
MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQPKARP
The following text describes a protein:
Function:
Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system (By similarity). Mediates the chemorepulsant activity of semaphorins. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity). Regulates mitochondrial iron transport via interaction (By similarity).
Subcellular Localization:
Mitochondrion membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.
Sequence:
MLLRLLSCCCWLLCSLRSSWASRNDKCGDTIKITSPSYLTSAGYPHSYPPSQRCEWLIQAPEHYQRIMINFNPHFDLEDRECKYDYVEVIDGDNANGQLLGKYCGKIAPSPLVSTGPSIFIRFVSDYETPGAGFSIRYEVFKTGPECSRNFTSSNGVIKSPKYPEKYPNALECTYIIFAPKMQEIVLEFESFELEADSNAPGGQTCRYDWLGIWDGFPGVGPHIGRYCGQNTPGRVRSFTGILSMIFHTDSAIAKEGFFANFSVVQSNTDEDFQCKEALGMESGEIHFDQISVSSQYSMNWSAERSRLNYVENGWTPGEDTVKEWIQVDLENLRFVSGIGTQGAISKETKKKYFVKSYKVDISSNGEDWITLKDGNKHLVFTGNTDATDVVYRPFSKPVITRFVRLRPVTWENGISLRFELYGCKITDYPCSRMLGMVSGLISDSQITASSQVDRNWVPELARLVTSRSGWALPPSNTHPYTKEWLQIDLAEEKIVRGVIIQGGKHKENKVFMRKFKIGYSNNGTEWEMIMDSSKNKPKTFEGNTNYDTPELRTFAHITTGFIRIIPERASASGLALRLELLGCEVETPTSIPTTPEVNGGDECEGDLANCHSGTDEGFKLTVGATGQSTETPTVEASPEEPDMTHSDLDCKFGWGSQKTVCNWQHDISSDLKWAVLNSKTGPVQDHTGDGNFIYSEADERHEGRAARLMSPVVSSSRSAHCLTFWYHMDGSHVGTLSIKLKYEMEEDFDQTLWTVSGNQGDQWKEARVVLHKTMKQYQVIVEGTVGKGSAGGIAVDDIIIANHISPSQCRAPEIDDSANKIGEEDSEIDKTGSTPNYALNEFNESISKKPGNVLKTLDPILITIIAMSALGVLLGAICGVVLYCACWHNGMSERNLSALENYNFELVDGVKLKKDKLNTQNSYSEAS
The following text describes a protein:
Function:
Sodium-phosphate symporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAALHQFDYIFALAMIFAFLDAWNIGANDVANSFATSVSSRALKYWQAMILAAICEFLGAVLAGARVTDTIRNKIIDVDPFTETPAGLMLLMMCALVGSSVWLTIATRLGIPVSTTHSIVGAVIGAAIATNGGGGVHWGWEGFSKIVASWFIAPAIAGGFAALIYLVTKYVVLERKNALRNALWMGYIYVGITFGVLTMLIVWKGAPNLKLDKLSTGATVGSIIGVGAVAALLYGIFLQPFFYRKLVKEDHTLRAWDIFYGPMLYYRGEVPPMPEGMNRHDYVVDYYKFVRTKEEYLEYYGHLNGYEGDDLTEDEEQQILVVSSNPEKHNGIESVESEEDERTNASRAAALESVDKSWKVLARNPKNWPKLFWKAISHGWTVDVIAAQKTSGHALSGDLRKMFSKAKKYDNKVEALYSFLQCVTACTASFAHGSNDISNAVGPLTTIYQIWSTNQTGKKADVPVWILVYASCALVIGLWTYGYNLMSNLGNKMTMQSPSRGFSMEFGAAVTTIMATRLNLPISTTQCIVGAIVAVGLCNGTIKAVNWRMVAWCYFGWIFTVPFAGLIAGILMGIISNAPKLGEVYQLS
The following text describes a protein:
Function:
Together with MWL1, contributes to secondary cell wall biology, specifically lignin biosynthesis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MHNLFLYSVVFSLGLVSFITCFAAEFKRTQKEDIRWDTERNCYVPGSHAFGLGSAAVLCFCLAQIVGNIVVFRNHRTRTKREDGYKITDLTLPTVLLLLSWSNFVVVVLILSTAISMSRAQAYGEGWLDEDCYLVKDGVFAASGCLAILGLGALTISATRIKVKKQQQLVQVVIKDQNQDQRRSMEEEQKHDEHQTNKSESVIHLVEEVSSTNISRI
The following text describes a protein:
Function:
Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein (By similarity).
Subcellular Localization:
Secreted. Note=O-fucosylation of Thr-201 and Thr-1037 is important for protein secretion.
Sequence:
MLGLKFLVLLSILWGRVFRLTNTQHSWTAPKDEDASLTPNHASASVSEILSLQVLSATQNPSTQGPAAAERSSEDDVLLQSTSQPSETSTPPEGRHQTPLEKTGTAVVSLPLSLQDKPSIKPSTGAGTVMLANATLKFLQSFSRKSDQQEVSTKSAGDMGNRSARETHLRRSDNSRNQRPSYQKPSFETTRGKNWCAHVHTKLSPTVILDTGSHLPSGRGSCGWYSSGLCSRRSQKTSNAVYRMQHKIVTSLEWRCCPGYIGPNCQLKVEEQQQLAHSNQAESHTAVDQGRAQQQKQDCGDPAMIQKLAEQLSQQERKLSLLQKKVDNASLVADDMRNAYLSLEGKVGEDNSRQFQSFLKALKSKSIEDLLKNIVKEQFKVFQDDMQETTAQIFKTVSSLSEDLESTRQAVLQVNQSFVSSTAQKDFAFMQENQPTWKDITDLKNSIMNIRQEMALTCEKPVKELEAKQAHLEGALRQEHSQIVLYHQSLNETLSKMQEAHIQLLSVLQVSGTENVATEESLNSNVTKYISVLQETASKQGLMLLQMLSDLHVQESKISNLTILLEMEKESARGECEEMLSKCRHDFKFQLKDTEENLHVLNQTLSEVIFPMDIKVDKMSEQLNDLTYDMEILQPLLEQRSSLQHQVIHKPKEATVTRRELQNLIGAINQLNVLTKELTKRHNLLRNEVQSRGEAFERRISEHALETEDGLNKTMTVINNAIDFVQDNYVLKETLSAMTYNPKVCECNQNMDNILTFVSEFQHLNDSIQTLVNNKEKYNFILQIAKALTAIPKDEKLNQLNFQNIYQLFNETTSQVNKCQQNMSHLEENMLSVTKTAKEFETRLQGIESKVTKTLIPYYISFKKGGILSNERDVDLQLKVLNTRFKALEAKSIHLSVSFSLLNKTVRELSMACRNASTGTCGQNALIPRWTKGSLPGSQSSQKSLTELVESIVEIKTQAALSNLTWNVDRLLSDTLANIVKPQKQIKLQKKPNTLKKTVNMTTILIGRTQRNTDTIIHPVAQEHSSCSSFPCQNGGTCISGRSNFICACRHPFMGDTCTVKIKEDDAVAPDFSKGSYRYAPMVAFFVSHTHGMTAPGPILFNDLSVNYGASYNPRTGKFRIPYLGVYIFKYTIESFSAHISGFFVVDGVDKLRFESENADNEIHCDRVLTGDALFELNYGQEVWLRLVKGTIPIKYPPVTTFSGYLLYRT
The following text describes a protein:
Function:
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
Sequence:
MYENKMKIEFLSKSENESFARVSVAAFISQLDPTIDEITDVKTAVSEAVTNSIIHGYENSKKGLVSIESEIKGREVTVIISDNGDGIDNIELAKQPLYTSRPDLERSGMGFTVMETFMDSLQVHSEKGKGTKIIMKKVFK
The following text describes a protein:
Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.
Subcellular Localization:
Late endosome membrane; Peripheral membrane protein.
Sequence:
MTDYPITGICIVADKNRCPDGYTVIETTTDNQDADLWKDKFLKKKITRYMCYTKDLKPLAGDKVLVDVMVIKENESIPSGYTCIQNTYDTSEPVLKKKLLVIQLFNRKATEKAITEIYLTSSKTKTKPVEVSARGDINGINMFLRMGPVMQLIPIASVRKAPVPAPRQNVNQPQSSTELPQQSGPTQLPYSWDKARSSRQSTLRTSQSLNLETDILSAIEGVPFQIDPTLQAITTISTFDVPRIPYKSEMEINDQFYYDFNFEAQTKQRLTMCDSP
The following text describes a protein:
Function:
Functions as a potential OhlL-responsive transcriptional regulator.
Sequence:
MFSFFLENQTITDTLQTYIQRKLSPLGSPDYAYTVVSKKNPSNVLIISSYPDEWIRLYRANNFQLTDPVILTAFKRTSPFAWDENITLMSDLRFTKIFSLSKQYNIVNGFTYVLHDHMNNLALLSVIIKGNDQTALEQRLAAEQGTMQMLLIDFNEQMYRLAGTEGERAPALNQSADKTIFSSRENEVLYWASMGKTYAEIAAITGISVSTVKFHIKNVVVKLGVSNARQAIRLGVELDLIRPAASAAR
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Sequence:
MADAPSGRSLVVDAVTHRYPSGALAVENINLDIKGGEIIALLGPSGCGKTTLLRIIAGFIAQTQGRIIIGDDIVDSLPPNRRAVGIVFQNYALFPHLSISENVAYGLAARGIDKASRQREAQRLLELVQLPTMAERLPRQLSGGQQQRVALARALAIKPSILLLDEPFAALDKNLRLDMQIEVKRLQRVSGITTLIVTHDQEEALSMADRVAVLSHGKLEQFGSPSDVYDRPQTLFVNTFVGSTNRMPGVVISADRTAAKVRLDAGAEIIARPAGGALAEGGRVTVCIRPEHLQFVGDETGFAGVVGMSLPLGATVVHEVTTADGSGVKVSQARIGETRALENGAAVRLAPLAPSLANAFPATL
The following text describes a protein:
Function:
Hydrolyzes ADP-ribose 1'',2''-cyclic phosphate (Appr>1) that is produced during tRNA splicing into ADP-ribose 1''-phosphate (Appr-1''p). Also acts on nucleoside 2',3'-cyclic phosphates.
Subcellular Localization:
Cytoplasm.
Sequence:
MEEVKKDVYSVWALPDEESEPRFKKLMEALRSEFTGPRFVPHVTVAVSAYLTADEAKKMFESACDGLKAYTATVDRVSTGTFFFQCVFLLLQTTPEVMEAGEHCKNHFNCSTTTPYMPHLSLLYAELTEEEKKNAQEKAYTLDSSLDGLSFRLNRLALCKTDTEDKTLETWETVAVCNLNP
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MSADYSHLSSAILEQCFGKVVQAVADCLFSATTRTLGQITSATKLSRKEVAFALAVLVKFRLVDFAASKANPFLAEYALRREDVLCLLRYPRYVHLVQTKYGNVGASISEELINSGSDTATGILLKCLAENENKAESPESYRNTFLEMITDHYIIKRPELLVGDDQDENVPKFETNECDFFRHPNIDLQLLAKIQKGEATLAEARDSHMVWHLNHDRFHQDFRDTIMVDAIERKLGENAAECFKFILKIMYNTTDPWERKLSNQITFVEIKQAIERKSNNLDLMKYLDQYISLLTEDSLGFFRRVGDMGGGVYVVDMEHAFESLAFACVECVITERFGSKAARIFRVIRCKKYIEQEDLQKEAMIPSKEAKSLAYNLFQEQFIHVKIIKKPGGGSNGPAKAFYLFQVKEKDTVRMLLDASYKSLYNTIERSNFEKNEHKGLIEKSQRLDSIVEAMKERGETDEYIAEIVETFTPPECEILNKVKNRIKTLSKAELTLDDTIFLLQMYQHHCTTLPTGIRKFK
The following text describes a protein:
Function:
Required for selective autophagy activation by ubiquitinated proteins. Implicated in sigma rhabdovirus multiplication and necessary for male fertility. Involved in activating transcription of Drs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSMTVKAYLKRGENANAEIRRFVIDVAVSSNYEYLSKKVAQVFPSLGDPDYFSLSWKDSEGDNITFSSDDELVEALGQINDDTFRIYVKEKKRCRRENRDAPSPGTSTDDGAGQEEQAYHPGVICDGCESRIRGPRFKCITCPDYDLCKQCESRGIHPEHSFVKFRKPQVGRSHHGGFFNRPGMFRPFGHPGWRHWWRHQQQQQQGGDASTTQNEQTQGTQGPQINVGCTMGPGLFGGPPPPPHGPHMPPPPPHGPNMPPPPHEFLRDIGQTVAQMLDPLGIDVDIDIDNQGNRTHCAGEPNFCGGGGNGHGRGKHGRRHGGKGHRGCRKTWAGCEQGSSMDVGQEAEPAPSGAARSQEKSGEAGGNTQNKEQDATQKQPEGTAEPMETTVKDGSAAAPNQSPSGSDDADWTLLENAGGKPSAPSQNPQEDPSYQYQTALNQMGAMGFDNEGGWLTSLLDAKGGDIVRVLDAIKIGNQPSFSGNSK
The following text describes a protein:
Function:
Essential for spermiogenesis and fertilization. May be required for manchette assembly in elongating spermatids.
Sequence:
MAAMQPAAQLQFQNLMSPSRPCLPQPTPIHQEKVAKLRPQIQNDSYPPKELTVLASQEVPRLRAVVESQAFRNILVDEMDMMVSRAATVIQANWKGYRLRQKLISQMTAAKAIQEAWRRFSTRRLMHSNKLTAKKAKREDDGDIPYHQPQQVRFHAPEDQSPLMVTKETQFPSSDNLVSSQATAGPCASRVPRGGLDRHTGPKHQPCMLTKTFQSSCLMRHLEGDSVKIRHVASKTIKVGTLEPAATGRYGQAIHGSLKTQTQTHTETDVPKVPLHIYQINKVPTKVCPAAAAAPKSPATMSTAPKSAPQTRPSSPATVTTVTTVTKMPAPTSPTSPMIRPLVPVPPNSSLSSTTPQMQVRSMVPGVRAQPPVSAVSPTIKALPRLGTFVTKAPLQTGPGFAVTKNLIQTRPVTRSQAQTCAVSTPSKTCQSSPTVKPSPQTRLAAMITKTPAQLRSVAAVFRTLCGGSTEAAVPSSPKSSSQSPVIAGNTASQVHLTNPKAKVTVSTKQTPAVVKVASQSYLAEGKGRCGPQGNLDIIPKPPPAKSPLEVEKMKPCPARASKKEAALKTNTTIATRALSWTKVMEDRSKALTQIEQRAEIVKVHFRVYMPEEITVTLSQAQLAVPLTKTCPQTRPSPCHARTLLASPCCKALSQSCTPSRLAPGTPEGRRPPVGLSASLSSSPLAAHLMSLTAQLQPAGEQARSVSRDHPTTSRPTSACPQSRSSGMTSVPPEVYPHTYSHISAPQHPMASILTKNSSQLRPPAEHVKTMNAKTAKAACQVCPSAKLNKAPSLAQLITCLAKVPSQAQIATETAKCLLTAHPPTDLSSKTQSQTFLSTSKASVQLWQHLGTLSTGPRAKPDDRSVAQPQPHSHAPNKTVQNSRSVATDPQGMLVPLMTPSGHPVCNAESWGDSGRPRTPPPSPMPNQAVSCHEDLAASIASLCADLVAMLGSPEDLRALLVKTLSQGEVRTALSQALSREVLGPSVVKAMPQGMLGMALMKALSWGELGISLSRALSRGELRPELSKATQGKLAEVLCKALTEDERATLSQALCQGELGAVFTQSLAQMAQRTGAFLPKASSKTVGSRMTTAPAPMEVTCSGSLSVAWGPTMGPVGARCSKGPVDAGLAAGQSWNSKVPNVSVRATAHAGAPPGIWPSRGHKPWDPSGAEAALDRKPSAELLMSVQAMEKVVVQAVVTIQACTRGYLVRRTVKVWHQWATIIQATWRGYRVRRNLERLFRATTIIQAAWRGYSIRRARTRHILLPTAWPEHGGRTQGNLDSRSSSEHRCFLSCQPDVCSVCQSLGPPVESPPSVVMLVGSQPRTCHVCGHTLSTRVVQGFGQGASVHSVSRWTSASQQSTLSQQHRACTIIQAAWKGYRTRRQLRQQQSAAKMVQAMWRGHYTRSCLTTDALLGTGGPWSISRDISRRTSRAYSLHWPGV