lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for the glucose and other nutrients uptake at low temperature.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MVIFAIFYVGRVLGYIVSKAANLVLWKQYRVTVSIQSLVFSPLAGKVHFKNVSVTSQDQLISVLKGTITWRYWLIGRYRRSGTADGARRCRFALKFEGFEYFVYNRNGVYDRIARELDGEDTSAEPTVSVPSVEEVIAELQDDPLIRRFLPVEFLHNKGAIVLGNKQTHSVAIMNYEKLAGTVSIEVPDDTRAPSSFRTEAKISNCTVAIKPNISYEVDNPVKIYVEPKRTARLWKKYKTLLGTVLEATLHAKRKKEQHQTPKWYDNWRGLSMYDVNLDEELDEEVKFDIEHHEYAKCTTVLKADQMDVTYSYGMPGTARVTDSDNAENPLLERPELDHSVDILVYDANCTYGPWANRQVQQCLRVFSPTVCRNFKLRTPEEIAQQTEPAAFKLSVTIMEDSVLRVPMKESSKDAAFLEKYKQTRDETRPFGWIDIRIAKESNITVRMAAYPTENGFENILHANLVDTTISTSVNHDTLLKAKSHDITVDFSYPYGWQDKAEWNFNVCSTQAELFVLRDHVYLISDLVTDFSGGEEVLYEQFRPFDYRFRWDIRGYSAYLNVNDANIINNPIDFGENCYLSVHGDDAEITFSLPITSIIQKYVTVDFNIFTPHFSLFLNAPPWHTFSELLHYKEIGRSKNFNIKGSYTSYSEVDVDNVDALNIACETDYIVVLCYGVILKCMLNVKVNYFGEMVHFRTTEEYVEELQRRNKQNPSTCRPFNSDGNVHDSDVVATESNEIIDASFDAFGGPPTIKKSALKRSINELDVWFTFISKGGCFFFPENIYKFDACLGFYFDNLEASLRFLNYYVDAAVSLDSIYFKRHTDIDARTLFKVIEDIGIPIDASDAYLSQFSFRLHKMLGIMPSEESYACEFDVRVDTLDVHCDLAVLKAFVNTLRNLAFGFKDVENSLQYEREQVFDLNKISCVIENVTVKLQNVDKDEDIWLSLNLPVTTLTSFDLANERYSRRSDLSIPELLFGIYRGDSESTCLGAFSTGVTVTLFERFEQFARCRVLQRKHILVNDAPFHRCSFMLPPEYKKMPIYRSLYGCIPPSSSLPLFPEPISADNFEVIFEKLLGEIYQEYASDSSYQITDDSISSTEHDYHNQTVNAAIGTSSSLFIRSQNHQQTLSSFIVEFDPIDGYLDLSATEFMLEIYKYLTEVSLDEAIDSLEIGIINQFIQTFGEDNGISEVRVLCPNISLSATNKQSKFSMFKLSSKIKNLDITSRIKSSDPNLKPDPEKTTLCYKIDYIRANIVQDGIVVPPKQPSQLFSCSIELLEGYLSYDKLSLLDNNVQSCSVTLSPGTDKLLFEFLNPFISTFDLLQRELSSFEDTLLASKREFLLNILRGGRDYEIQHDPPVITKPANITRFSNRHIRSAESWRIIMRLRHILNYLPQEWHQSFTRHLGTQDFTSPEEAGKEFLSIFSDWRSWEPTDVQGSFVHEKVFTKKRSRPFAALQGFTFSSDDIRLNMKDDARVPITVKGVTLGIRNNGLAPEQVDGRTEGSMPDPDYISFCTTDEVVMRVDRSFVKTLKEFRDLIHRFKIGGPVGTAKHDNVSLFSNITFQFGKLYVVAKLAGVYLRICLDNLSALMLTSQSSVESKVISSSTLSFDHMQAILGYRSFRFMTIDIDMFSVLLHYLPGQGCYSIDWKARKFHIDSSSATTKDLTESLPYVRDEIKYLVEALVPELFAEPPIERESSGNKIHAVLFQGQVANITLKLQILSPFIILYCAENFELQAESTDSVIFDLNSGESYMEISSAKQKLDYFKYTHTCLKLSGTSSSARLFEHISCDIGILKLSVFDLKTRITDLLQDIKAALFSMKSLSDILNISQSSPTASAFGSWFSILPDNLSLQATYAGLLLGFGHTLYILEFNNFEAKHTRDGLPDAITPRPCFKVDHSIESASFLIKDRRIDDRLAKVVDFAVNFNMVHDTDLCIQSVQIESTHLKITLAPMTVVRLLSLINEFGIIRKQFTEESIYTPSSAHNNSTATECLEPSVWRLIIKSGHILSHDFSIVWLFDIPNSSADGLICGYDRLFSVYEKPYGKLTLLNAYFSAAKILASEADFYSSVVRKQRINTSYLSDMQLRYWFTEDSENTDLFIRIHGAKLAVDISAEIVTLLEETIQSIQTFNNLKKALVDPFRTKKQDSDISKEPYNWNNQLATGVRSLNCIINYAGVTLKLHSHDGRGDASPLELTSPSYKVAIDYKYFPNLEKTHRFRTLITATPTHNTFYSTSAFLIHDLCYRFSKLLKTSSTENKSSSASTSSSIKVEGSDNSTLLGSIDLVIILNVGKQEVTFSCEPKAKVQATVGFEKFDIKIFNNNINDEESLCLAIEIENLMTNSRHIYSREVCASLKLRHISMVFDIMGSQVRRIYGSTLISSPLFYFNMKQLQDLKLFIDQWFPQKTPMNTGSYPEGVLVDDISRSIGSKFYKGSSSSSFTWGYSVIVAGSCAEIELGPSLGVLNVTSEDVWAISKQQVDWSQQLDLNMGKLDVTSSGRLGGNFLVRNAHLSLELKWPNPKDFFQVPLVCVKLGSDTVDTKLSFDYHTFFISSLKQGYASLFNERDEDGSLADLLSVTVSFESVNIFLTALAAANISDIKNSITRLKKDNELSYLSSFLASDQPSDEPEEDGGIFDTLSLLRTQLSLNLGVFRLQISPTSLFDSDVLILTATKMMANTGIQADIKIKTDLHWQLDDVSLALLPFNNSLDESYLATMEVGKYIELSSTIQGGAIFSAPSIVVNMTTWQEPQSNVIELLYSTSFGGTVKIRWNLGPISFIKDMWQAHMNAMQLREGYYHGLAESGVAVTPLNSKAVPLEMHLGSDYQYLPLQEPDIEMPRIKDLGDATPPIEWFGVNRTKFPGFTHQFVIVPLQKLARTAEKEYEKILGRAL
The following text describes a protein:
Function:
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
Sequence:
MSQYFTLFRIEPAFDIDTENLEQTYRALAARFHPDKFASASAFEQKQAVMMSSTINDAYRTLKNPIDRAAYLLKTSGIDADAPEHTAFAPEFLMQQMEWRETLMEARAGNDLESLKNLDNEIRDEQEKLFCGLKQSFARQDYDTAAQQVRQGRFLDKLRNEISSAL
The following text describes a protein:
Function:
Binds to histones H3K4me1, H3K4me2 and H3K4me3 in GST pull-down assay. May facilitate the recruitment of effectors to mediate gene expression (By similarity).
Subcellular Localization:
Nucleus.
Domain:
The CW-type zinc finger domain is not required for nuclear localization.
Sequence:
MGGGRRGGRREAEEGVAVAGRSRGVAAAAARHEVAGELELASAGGLGGGGGDELVDPDQLTYIHNVFKIDLYSHVLVNLLVTICKDEKLQNILGHFQKEFEGGVSAENLGSQYGGYGSFLPTYQRSPPALSQSGSPAVLPNHGSASRSPYIPLESVQKNHFVKQAIDGRRKNNYCQRTSSENDSNHSQQLLNSGPEQKTAKIRIKVNNKCLERNNAAIYSGLGLDISPSSSIDDSPQWSIEAPESKLFPDESADTIFQIMTCHSVPGGLLLSPLAENVLELRQKSTAVTKKHEAPVYDNDKEELQRNCCHTSSAAPDNNYQLVKKIKLDEQRDHLPEFENSKYRHKNATIMKKGAKPELKDISDEIDSIRAPRCAKTEKHAVGESADFIADTSGRLKEAKNGQFKGKGSTQSSLSIIDVKAANSANDDKHPKGKAKLKVTLVRNAKMESSLDDGFSHKTKSDKCNDQPVTTSSQLQIDPAKKTSLKRDRGKVVCAKDEPSQYKSKELRSLVDAESMGTTTENVAGNSSELLKGKKVSALQASLFGKKLKIKTHKKPNYDTTRKPNGENEGYVLDHRNGSTYLHTEDKSLKTEKESATSGLTDKDFSGGGNDGDHKISPIVVDKSASMPSRCKNETTEASMAVPASEPVDQWVCCDKCETWRLLPYGMNSDTLPKKWRCSMQSWLPGMNNCKLSEGETTNAIRALYVVPIPENNISLDSRCDTATLVRSNDAAIMSDNLGMPEISKSSKKLHAPRNRDGLDCFPKLKEKQKRIESSDKGEKSTVTISSGQTMAKDRMHRKRKTSGADYDNLIASKKLKKVYNEPPKHQPPQFELSKSRPSTKGSLKELPKHTNISPGMGKHALPSSGKQFCDGDNSDRGARASDAGKSDPRDLFIKKNKSKQMQLRQHGPDPRPSDAFAKHVVKEVLSESNAAKEKLGSDLKFLKVDDHEKSAHARGPVTGTNSNAIFSEKEDLIEQHLENIHFQHPLLSESSVRRNICNVQASTAATSSSSKVSSSHKNKPEFQETRTSPVESVSSSPLRTSDKKHLDRHRTNSYAVAEIVHSQESVKTGASCSKEKYGFECGSDHTKPHVSGCSNRVMHQDALEDGDLDKQNILTNGVFNNRSSGLGIRNDQGQPNSLVEQKVNSHVLPIHGSGDFRRPTPDQNGKTLPQYNSNQSDQAKLSSGKHPTQVRPDKGNVEYIDLKTNPSTVAGSKLLPGLNNKVNGNASNKSKQSVVENMKHAAIHVDASTPINASALLKEARDLKHLSDRLKGKGDDLESANICFEACLKFLHVASLKEAAGVDSSKQGDPINTMTLYSDTGNLCGFCAREFERLKKMANAALAYKCVEVAYMKAAFYKHPGAIKDSHALQAASVIAPPAESPSSSASDVDNLNNPSTIAKIVSTRGLCTSQIAKNPISRSNHHLMGLLAYSFSYDPFCLLDKVEDTNYAFEGTRKSQSAFFSYLSGIEKDQADGIALLTEVLNFSFHNVKGLLQLIRHSLECINHERFK
The following text describes a protein:
Function:
Probable transcription factor involved in the regulation of the transcription of genes involved in cell rescue and defense, as well as cell cycle and DNA processing.
Subcellular Localization:
Nucleus.
Sequence:
MNFSLSKQSSEKQSSYTDKSRSPNIGMCTVNYKSNLPLQVSAVDQLSTGKGTQFYGHNSYKNERECYNSTKINLPPISSLLPNFENNTPPNVDSRVQFPPQQVYQSMNVVPIVNEIYTPISMNATSDQYPIYYTESQQPIPHSQSPHLTSSAPLMMPVMVPTVYKPLTPYDKEPITIASEPNFTAISMASHPNAALELCHDRPKSVPPGYGVLPTMQEASNGRTKSEPGAVLNGSATFSDWKTDTRISSTKLRKQCPVCGKICSRPSTLKTHYLIHTGDTPFKCTWEGCTKSFNVKSNMLRHLKSHERKRNKVLNTT
The following text describes a protein:
Function:
Permease involved in the transport of the cationic neutral or acidic amino acids.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MGCLRSLVRRKQFDSSNGKAETHHHHQQLAKALTFPHLIAIGVGSTIGAGVYILVGTVAREHSGPALALSFLIAGISAALSAFCYAELSSRFPSAGSAYHYSYICIGEGVAWLIGWALILEYTIGGSTVARGISPNLAMIFGGEDCLPTILARHQIPGLDIVVDPCAAVLVFIVTGLCCLGVKESTFAQGIVTTANVFVMIFVIVAGSYLCFKTGWVGYELPTGYFPYGVDGMLTGSATVFFAYIGFDTVASMAEEVKNPRRDLPLGIGISLLLCCLLYMMVSVVIVGLVPYYAMDPDTPISSAFSSHGIQWAAYLINLGAVMALCSALMGSILPQPRILMAMARDGLLPSYFSYVNQRTQVPINGTITTGVCAAILAFFMDVSQLAGMVSVGTLVAFTMVAISLLIVRYVVPPDEVPLPSSLQENSSSHVGTSIRSKQPLLGKVDDSVVDKENAPGSWVLNKKNRRKFAGWSIMFTCIGNFLLSYAASSFLLPGLLRYSLCGVGGLFLLVGLIVLICIDQDDARHSFGHSGGFICPFVPLLPIVCILINMYLLVNLGAATWVRVSVWLFLGVVVYIFYGRRNSSLVNAVYVSTAHLQEIRRTSGHSLA
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MAALPLGPSNEQEPPEGEAVLEGLAMAGLVAVLRQLGDLAELAAEVLDGLQDQVMAVSARGRRLAMRAKRLQADLTPSIHNKPNHRLDWHPRRNLNHHHQHGVGEAPPRSIVDHIKRCRGPPNLSALDRFDAHGEGACLKRYTDPSFFRTCHSDDCRSQTDASEKQSLGFLSMLRQLTHRQTPGSLINLPKYYESSAEKDYSETGSSPEPHMEMEKAKENRPGQSNDSPTSNCCSDYVGNCSDELERTSSFEAWLSPGARFSTHEYETADGTVHHAKQDSEAAETSCNKGVSIEDTNADTPPLVPIPPMQWLSVKVHTGPITYRNSFGRNRVNRAGGKILKTTELSEPAIHSYEAWSEAEGTNQQQVFNHKGPEISSCRGTTVSDSEANKPSQADSASGQGDEDSLHHENVLFSAVEQLAGMSPPWVPRPKHPLPEVASQDRITLRNGPSPIHRSRSILDSRTAMLHQIKDKDK
The following text describes a protein:
Function:
May function as sodium-coupled metabolite transporter across the chloroplast envelope; May operate as a cation/H(+) antiporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Plastid, chloroplast envelope.
Sequence:
MAEDDGSKCSADVLAGSYFMARLMVVLGLMASVLALSGLFHSGLRRLGQPSIISHILAGVVVGPTVLGRMVNLRQLGLEDPGMALDDAIYYLRVIFMFFTGLEMDLCYLRRYLRASLVLASGGSALCLLLAAVAGPFFYGLLHPGKKNFYPDGIYASTALFMLVLTSTASPVLIRIVTELKLTGSETGQLAIGTAFANDIASLVVVSIMDVDWTTYDKDGKARPDDLLGQPMAKLIIFLFLSLNVWIAIRMVVWLVRLLNRAKKGRQYVSMYVLCAMLLFIVNTAQRLNVFGYSASMTAFLIGLATPRDGPTARTLIDQLTYPVHQIVMPLCFGVTGARLDFTKLGRFTATQLIIVVAFTTLLGTTGRVAGTVAAGRMIGIPARETLVLGLLLNVKGYADILAIKLGDKAGIWGDAAQSVLLLSSIINTLMAGPASAAIVRQQRLAFQYRSHCLQDLKLDEELRVLVCVHGAGSVHAMLTLAEISKGTTPVAIYILHLIELMTAHKYAITHLYHPKGGDRDDNGRWGHTREIDQVVAAVDRFINDTIVAVRPMTAISNLVSMDTDVCNAVEDTRASLVIVPFHKEQRYDKRMVCRREGRRELNQRILQRAPCTVGVLVERRLGTIAIAERQPTAEGNQQSGSVDPEAKGSAPAHDVVAVFLGGPHDREAVAYATRLAAHPSVSVTVSRFLPERASMDATAEARSTTPMSTTNDSGGDDDHVTLMVEGKVDEEGMADEEFMAEFYARFVEPGHVSYTEMYVRNGVGVVESLWSMVGMYSLFIVGKGGGGGGAAAEMTKGMGGLNEECPELGPIGDFLSSDDLLGYGTSVLVLRHHDVAKKTRQTQ
The following text describes a protein:
Function:
Acts as a co-chaperone.
Miscellaneous:
MISCELLANEOUS: Present with 33700 molecules/cell in log phase SD medium.
Sequence:
MSDKVINPQVAWAQRSSTTDPERNYVLITVSIADCDAPELTIKPSYIELKAQSKPHVGDENVHHYQLHIDLYKEIIPEKTMHKVANGQHYFLKLYKKDLESEYWPRLTKEKVKYPYIKTDFDKWVDEDEQDEVEAEGNDAAQGMDFSQMMGGAGGAGGAGGMDFSQMMGGAGGAGSPDMAQLQQLLAQSGGNLDMGDFKENDEEDEEEEIEPEVKA
The following text describes a protein:
Function:
Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity).
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MEVSRRKAPPRPPRPAAPLPLLAYLLALAAPGRGADEPVWRSEQAIGAIAASQEDGVFVASGSCLDQLDYSLEHSLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLGGLLLTGWTFDRGACEVRPLGNLSRNSLRNGTEVVSCHPQGSTAGVVYRAGRNNRWYLAVAATYVLPEPETASRCNPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLWNGSIYFPYYPYNYTSGAATGWPSMARIAQSTEVLFQGQASLDCGHGHPDGRRLLLSSSLVEALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVDSSRELCQNKSQPNRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPACVETGCAWCKSARRCIHPFTACDPSDYERNQEQCPVAVEKTSGGGRPKENKGNRTNQALQVFYIKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVIDNLIISHELKGNINVSEYCVATYCGFLAPSLKSSKVRTNVTVKLRVQDTYLDCGTLQYREDPRFTGYRVESEVDTELEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVLFDEKKKCKWM
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication and thus may regulate the initiation of DNA replication (Probable). DNA-binding may not be ATP-dependent. In a SIR2A/Sir2-dependent manner, binds to and silences telomers and subtelomeric repeat regions (TAREs). In a SIR2A/Sir2-dependent manner, binds to promoters of var genes localized next to TAREs resulting in their silencing.
Subcellular Localization:
Nucleus. Chromosome, telomere. Nucleus, nucleolus. Note=At the late ring stage/early trophozoites, co-localizes with SIR2A/Sir2 to telomeres and subtelomeric regions (TAREs) in the nuclear periphery. Also, partially localizes to the nucleolus. In trophozoites and early schizonts localizes throughout the nucleus. During early-to mid replicating trophozoite stages, colocalizes with PCNA1 and ORC1 to distinct nuclear foci which probably are DNA replication origin sites. In schizonts, relocalizes to the nuclear periphery and cytoplasm. In late schizonts, expression decreases probably due to proteosome-mediated degradation.
Domain:
The N-terminal domain binds telomeric DNA and is required for the silencing of telomers and var genes; The C-terminal domain binds ATP and is required for the binding to DNA replication origin sites; Leucine heptad repeats are essential for the binding to telomeric DNA.
Sequence:
MTPKKKIFQNFQANDNEILSPTKKGIKLNVSKLNILNFENTIITKEKTNYEYKASLNKEIDEVLNNNNIINTHNNKKNNLNLYDYNNIKNSTHEFYIDLNEQNKQTIKYNDNKFTPINKKEKYNLDETSSSSISSSLTNISSSLTNISSSLTNISSSLSNSLDEKKKKKKIKKNNSTIINILNNNNNNSNIHHNNKHNIYNKYNISKKPQNKEIHTLPSNHQIKKKSNNTYNTCQQKMKKNISKKNTHSIKNNQNDKNKEKNKEKDKNIKKDRDKDIQTKRTSHQSQDQNNHFERRILRSYTRNNDNVKNNLKNNINNNNTLKRSSQSVRIDSDLSSAHQNKRIKYDEKNIIHRNNNNNNNNNNKTTSNNHNKNNKINNNNPSENYKKQTDTKHTNNTQNNKYNKTKTTNTFKHPSKDHTDVNTKTFKSRYINTYTMEEVQKSIKSNTIKLVQENSCEYQDGIIYESIQINDEEYSIGEDVLIFYTPNNNTYNAKSDDKKNQNNNNIKENIYLLKKGKISSFYKSTNSKVIEVEICFYYDESDEQRIRELEKKQTSRRCKEDFNIYLDDDTKYYNLLGNIHFTILDANYIYKKIYVYNEIETFEEDTHARKGKNKFLCTHFIKDKEDRLCFIPNEDHWDNLVLGSSDLYYYFANEKKLNKNKSLKLIIEKLKINDKINDTQANQKKNNKKEYMNKAQTTTNVKANTHTKTLNDHNKSKTTKNKESSSTSFLQDVKKKSDPHNNDFQSSLKEDQENYYINLLKNIKDPTDKAIRMMQLDVVPKYLPCREKEIKEVHGFLESGIKQSGSNQILYISGMPGTGKTATVYSVIQLLQIKSRKKLLPSFNVFEINGMNVVHPNAAYQVFYKQLFNKKPPNALNSFKIIDRLFNKSQKDNRDVSILIIDEIDYLITKTQKVLFTLFDWPTKINSKLILIAISNTMDLPDRLIPRCRSRLAFGRLVFSPYKGDEIEKIIKERLENCKEIIDHTAIQLCARKVANVSGDIRKALQICRKAFENKRGHKIVPRDITEATNQLFDSPLTNAINYLPWAFKIFLTCLIIELRIINEFVIPYKKVVNRYKILIETSGKYIGMCSDNELFKIMLDKLVKMGILLIRPYIPLENISKNKSKEALLGFNESSKKGNNQKITRAQVSPDIDKESGDMGIELNVETQLIITALMKDPDCSKKLNFY
The following text describes a protein:
Function:
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Also plays an important role in establishment of the anterior-posterior body axis formation during development.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Sequence:
MAGAIIENMSTKKLCIVGGILLVFQIVAFLVGGLIAPAPTTAVPYTAIKCVDVRKNHHKTRWLAPWGPNKCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEISMDVSLGYRDDMFSEWTEMAHERVPRKLKCTFTSPKTPEHEGRYYNCDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVSEGHWKWGGVTVQVSSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVHSGEELQLTTTITHVDGPTEIYKLTRKEAQE
The following text describes a protein:
Function:
Phosphatase that has high activity toward pyridoxal 5'-phosphate (PLP). Also active at much lower level toward pyrophosphate, phosphoethanolamine (PEA), phosphocholine (PCho), phospho-l-tyrosine, fructose-6-phosphate, p-nitrophenyl phosphate, and h-glycerophosphate.
Sequence:
MKILLVFDFDNTIIDDNSDTWIVQCAPEKKLPLELKDSYKKGFWTEFMGRVFKYLGDEGVREDEMKRAMISMPFTPGMVELLNFIRKNKNKFDCIIISDSNSVFIDWVLEATNFHDVFDKVFTNPAAFDSNGHLTVEKHHTHSCTRCPQNLCKNVVLVEFVGEQLQQGVNYTRIVYIGDGGNDVCPVTFLKKNDIAMPRKGYALQKTLYRMCQNLEPMESSVVSWSSGVEIISYLQFLIKE
The following text describes a protein:
Function:
Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The JAMM motif is essential for the protease activity of the CSN complex resulting in deneddylation of cullins. It constitutes the catalytic center of the complex (By similarity).
Sequence:
MQAAQQSWELENTISLIDPQRDALYRYDEETHKALSAARPWAKDPHYFKSIRISAVALIKMTMHARSGGSLEVMGLMQGYILPETFVVTDAFRLPVEGTETRVNAQEEANEYMVSYLQSCRDAGRMENAVGWYHSHPGYGCWLSGIDVTTQDMQQLGGPFVAVVIDPERTISAGKVDIGAFRTFPKDYTPPKEGNEDEDYQTIPLSKAEDFGAYAHQYYSLEVSFFKSSLDTELLSQLWNKYWVATLSQSPLFTTRDYGSRQMMDLSQKVRRAARGIESSGSRGGATTPKDQQLEKIVRDGQRIVSEEVKGLLAAEVKMKLFQGIGEGTQTGAS
The following text describes a protein:
Function:
In association with the non-catalytic regulatory subunit DHSp, catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF5A precursor protein to form the intermediate deoxyhypusine residue. Regulates protein levels of its regulatory subunit DHSp. Required for cell growth and survival.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MAELAKSAVLVSSCTDDLLGDAKQVVVGPNQEDLHSAEAVLNRYSTVGFQASNLARAFSICEMMLTPQSPSPSLMPTEGDQASESPVMVQPTLFVGVTANLFGTGCREAIRFLCTECVPLPNGVEPATPLDDMAGISCDGTGALKPSPCDSRALIHVLVVSGGAMEHDIRRACESYKLSRDGAEEEGEQFHHPVERDRSRSKGTDCHFGNVRYNSSGVASRNLFSCVMRCLVKRLAEAQRKEKANREAAPIPEAYYDVCSWAITPSTLWYMAGLWMADIFTEALQETGEVTDEKVASEEGLKRAKSTVLYWAARNGVPIFSPSLTDGDIMEFILTAGDTGVPLLQLDLVADIHRLNRLAMRSRRTGMMILGGGVVKHHVCNANLMRNGADYAVFLNNAQEFDGSDAGARPGEAVSWGKLRLDSTAVKVYSEVTIVFPLIVVHVFVAWVRMMRSKGKENIRS
The following text describes a protein:
Function:
Multidrug efflux pump that acts independently of NorA and is one of the factors that confers resistance against diverse quinolones and chemical compounds. Extrudes norfloxacin, ciprofloxacin, cetrimide, tetraphenylphosphonium ion (TPP), sparfloxacin, moxifloxacin and ethidium bromide. Also contributes to the efflux of tetracycline.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEKPSREAFEGNNKLLIGIVLSVITFWLFAQSLVNVVPILEDSFNTDIGTVNIAVSITALFSGMFVVGAGGLADKYGRIKLTNIGIILNILGSLLIIISNIPLLLIIGRLIQGLSAACIMPATLSIIKSYYIGKDRQRALSYWSIGSWGGSGVCSFFGGAVATLLGWRWIFILSIIISLIALFLIKGTPETKSKSISLNKFDIKGLVLLVIMLLSLNILITKGSELGVTSLLFITLLAIAIGSFSLFIVLEKRATNPLIDFKLFKNKAYTGATASNFLLNGVAGTLIVANTFVQRGLGYSSLQAGSLSITYLVMVLIMIRVGEKLLQTLGCKKPMLIGTGVLIVGECLISLTFLPEIFYVICCIIGYLFFGLGLGIYATPSTDTAIANAPLEKVGVAAGIYKMASALGGAFGVALSGAVYAIVSNMTNIYTGAMIALWLNAGMGILSFVIILLLVPKQNDTQL
The following text describes a protein:
Function:
Toxic component of a type I toxin-antitoxin (TA) system (Probable). When overexpressed kills cells within minutes; causes collapse of the transmembrane potential and arrest of respiration. Expression leads to membrane depolarization; when protein levels are high enough depolarization probably leads to lowered metabolic activity which in turn induces some cells to enter the persistent state in which they transiently survive antibiotic exposure. Its toxic effect is probably neutralized by antisense antitoxin RNA SokB, which is encoded in trans on the opposite DNA strand.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MKHNPLVVCLLIICITILTFTLLTRQTLYELRFRDGDKEVAALMACTSR
The following text describes a protein:
Function:
Necessary for formate dehydrogenase activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MWGGEMNIFKQKEREFALNRIPVLKEKFPESNQILNFLSHILEYHNSIISEISDLSISLDNQNIESRLGKGKPALKLSEYDFEPFLKYFYPLLNIVYEHGTPQMKERVEHLQSLEKKEILSLISSFLENGISDDMLRFFLISYLQPILYTFADKVKFEHERWFKNYCPVCGSKPSVSFIMDTEDWEGARFLRCSVCLTDWLYVRTKCVNCGNVEDDSLDYFISSELDYIEIQTCKKCNSYIKIIDLRKDGLAVPDLEDIASVSLDLWAQEQGFIKVERNFMGY
The following text describes a protein:
Function:
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
Sequence:
MEELREAFEEGKPVILIDRNRENEADFVFPAQLITEDVVSFFVTYGKGLFCVTADEEDLLKRGFVKLSSNYGANYFVPVDWGTGTGISALERAETCRKLAEGRYFHEFRYPGHVTVIGGIGFQRRKGHTEASLEISELAGFSRHAVIVEILDEKGNSHNLDYVLKLSEKFSLPVLEMDDVWREFVKRKLLMKKKAEATLPTDFGVFKVVSFENHLDGKEHFAIVKEPLEDPVAVRIHSECVTGDVLSSLRCDCGSQLANFLRYMSAHGGILIYLRQEGRGIGLSNKIAAYSLQDKGLDTVEANRVLGFSEDERDYAPAAQILKALGIERVLLFTNNQRKTVGLEKYGIEVVETKRLYGRVTPHNRFYLSTKMKKLGHELEEIFREVNS
The following text describes a protein:
Function:
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
Subcellular Localization:
Secreted. Bacterial flagellum.
Sequence:
MRWTQSHALYVQGHSDASAPNWLTPSTQHQPIFGNNNMTRINTNVSSLVAQNRLQSSNNDLQQSLTRLSTGLRINSGSDDPAGLLASEALRGEITGLTKSISNTQRASQIISTADSALGQVSNLLNDVRGLVVEAANSGALSKEEIAANQLQIDSSLEAINRISQTTTFQGRKLLDGSQDFVSTASGVSSISDISIDQANLGKTGKIDVEVVINSAATQATATAADSGFSAAAQATATTPAGINSVTLGDATNNLTIEGQFDSVEVIDGGASSATSASITDGVLTISVDAAATVTGASVVTALNGVSGVYAEETGTVADVNASAATDATAIEGAGLSITAADSGGDFNNVQINYVAGDAAATTASYDADQKALTVTIGTGAGENNLAAIAAAINAGTTEFDAEVADGTGATPAAGKVTEYGEFTIDTADLPAVGSTGNTGGEVLNADLVFQLSGENGAETFNFGAGTTKDQIAAAVNLVSDSTGVSADATGALEFSSTGFGSDALVDIDVISEGAGGTFKGSLDNTRSTGADIVATVNGVEANGSGNSLSINTSSLDLSLTVDDGSSTNFSFSITGGGATFQLGPDVTSTQQASLGIGSVSTGQLGGASGRLYELGSGQAKSLTNDVEGAAKVIDEVIGKVVGLRGRLGSFQSTTLESNLVSLNETKANLQEAESSIRDADFAQESANLTRAQILVQSGTNVLSLANQNPRNVLSLLG
The following text describes a protein:
Function:
Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
Sequence:
MGKKGNKRDKKPAQFKKIYELLSKYTQVIIVGLANVGSKQVQDIRRILAKKNALLVIGKNTLFKKVLATRVQELPDTHEYFEDLRKFGNAIKELDSLKNQVAGKVGFVFTDTPVFDLKPIIEENKVETPARVGAIAPIDVVIPPGPTGMDPASIQFFHALQIPTKIEKGQIQITKDFVVLKTGQKVGQSQAVLLQKLGKKPFLYGMEVLSCYDNGSILNKQQVSVNLNDILAKFQQNVQNISAISLSNGWVNEASAPYVLANAFKDLAAIGLQSGIHL
The following text describes a protein:
Function:
Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGDQGTELKTLSPGALLEEDSCPGERPDLCHMATIAFTGGWRVLIRL
The following text describes a protein:
Function:
Could be an iron-sulfur flavoprotein with NADPH:O(2) oxidoreductase activity.
Sequence:
MGDIMRPIPFEELLTRIFDEYQQQRSIFGIPEQQFYSPVKGKTVSVFGETCATPVGPAAGPHTQLAQNIVTSWLTGGRFIELKTVQILDRLELEKPCIDAEDECFNTEWSTEFTLLKAWDEYLKAWFALHLLEAMFQPSDSGKSFIFNMSVGYNLEGIKQPPMQQFIDNMMDASDHPKFAQYRDTLNKLLQDDAFLARHGLQEKRESLQALPARIPTSMVHGVTLSTMHGCPPHEIEAICRYMLEEKGLNTFVKLNPTLLGYARVREILDVCGFGYIGLKEESFDHDLKLTQALEMLERLMALAKEKSLGFGVKLTNTLGTINNKGALPGEEMYMSGRALFPLSINVAAVLSRAFDGKLPISYSGGASQLTIRDIFDTGIRPITMATDLLKPGGYLRLSACMRELEGSDAWGLDHVDVERLNRLAADALTMEYTQKHWKPEERIEVAEDLPLTDCYVAPCVTACAIKQDIPEYIRLLGEHRYADALELIYQRNALPAITGHICDHQCQYNCTRLDYDSALNIRELKKVALEKGWDEYKQRWHKPAGSGSRHPVAVIGAGPAGLAAGYFLARAGHPVTLFEREANAGGVVKNIIPQFRIPAELIQHDIDFVAAHGVKFEYGCSPDLTIEQLKNQGFHYVLIATGTDKNSGVKLAGDNQNVWKSLPFLREYNKGTALKLGKHVVVVGAGNTAMDCARAALRVPGVEKATIVYRRSLQEMPAWREEYEEALHDGVEFRFLNNPERFDADGTLTLRVMSLGEPDEKGRRRPVETNETVTLLVDSLITAIGEQQDTEALNAMGVPLDKNGWPDVDHNGETRLTDVFMIGDVQRGPSSIVAAVGTARRATDAILSRENIRSHQNDKYWNNVNPAEIYQRKGDISITLVNSDDRDAFVAQEAARCLECNYVCSKCVDVCPNRANVSIAVPGFQNRFQTLHLDAYCNECGNCAQFCPWNGKPYKDKITVFSLAQDFDNSSNPGFLVEDCRVRVRLNNQSWVLNIDSKGQFNNVPPELNDMCRIISHVHQHHHYLLGRVEV
The following text describes a protein:
Function:
Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MRAVLSLLTLLCSAPGAADKKDRSYEFSLESHEYPISSEPAHWADQHPYCGGRRQSPINVVTRKAQYDSSLEPFTFEGYDQTHSVTAENLGHSVHFALSSSVRTQGGHMPDWYKAVNFHLHWGWEAGPGSEHTIDGEQFPMELNTKQSVNTTKHIMGGNVLEQCMNALAVLSLQESSQDNPYYKVLIDALDEVKHAGNRTIITALQLVSILPKPQDLRKYYYYSGSVTVPDCDEAVVWAVFETPIRISREQLTAFSQKLLFRTEKPMKMTFRPTQPLNGRVVLRSSA
The following text describes a protein:
Function:
Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MGRSSKDKRDAYYRMAKEQGWRARSAFKLLQLNEQFDLFKGVRRVVDLCAAPGSWSQVLSRELVQNVPASERPTIVSVDLQPMAPLEGVCTLQLDITHPDTLPIILSHFGDEPADLVVSDGAPDVTGLHDLDEYIQAQILLAAMNLAACVLRPGGTFVAKIFRGRDVSLLYSQLRLLFKHVTCAKPRSSRASSLEAFVVCQDFCPPEGFKPNLKKPMCITDYECIGDIAPFLACGDLNSPDADATYPYAVSKNSKPLDAVQPPTAPPYKKAIEMKRSAQL