lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for biogenesis of the 60S ribosomal subunit.
Miscellaneous:
MISCELLANEOUS: Present with 8150 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAKRRQKKRTHAQLTPEQEQGIPKSMVIRVGQTSLANHSLNQLVKDFRQIMQPHTAIKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFSTSKRSGEDDQDVNVEKVIVSMFQNIFPPLNPARTSLNSIKRVFMINKDRETGEISMRHYFIDIREVEISRNLKRLYKAKNNLSKTVPNLHRKEDISSLILDHDLGAYTSESEIEDDAIVRVVDNQDVKAKHSQSLKSQRTPVEKKDNKEREKETEEEDVEMEEPKPSENLQPTPRKKAIKLTELGPRLTLKLVKIEEGICSGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRKKEQEENIAKKKAVKDAKKQRKLERRKARAAEGGEGQGKDDAMSDDESSSSDSEHYGSVPEDLDSDLFSEVE
The following text describes a protein:
Function:
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1 (By similarity). Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium (By similarity). Essential for the survival of peripheral follicular B cells (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MEPMPSATDGGDRSATPSGLSASQRRAELRRRKLLMNSEQRINRIMGFHRPGSGAEEENQTKSKPLDSDILNPLGVPSVSKRVVLGDSVDGGVTDYQPSGGADIRGAQLGDKLDSFIKAPECSSKDGVELRQRNRGDLTADSAPRGSHHGLEQYLSRFEEAMKLRKQLISEKPSQEDGRTTEEFDSFRIFRLVGCALLALVVRAFVCKYLSIFAPFLTLQLAYMGLYKYFPKGEKKVKTTVLTAALLLSGIPAEVINRSMDTYSKMGEVFTDLCVYFFTFIFCHEVLEYWGPEVP
The following text describes a protein:
Function:
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
Sequence:
MMEVESSYSDFISCDRTGRRNAVPDIQGDSEAVSVRKLAGDMGELALEGAEGQAEGGTPDKEASNQPQSSDGTTSS
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli and in M.smegmatis counteracts the ribonuclease activity of cognate toxin MazF6.
Sequence:
MKTAISLPDETFDRVSRRASELGMSRSEFFTKAAQRYLHELDAQLLTGQIDRALESIHGTDEAEALAVANAYRVLETMDDEW
The following text describes a protein:
Function:
Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
Subcellular Localization:
Secreted. Bacterial flagellum.
Sequence:
MASVISTSSSGLDIPTVVSTLVSRQKDPEQARINKAGTAATTQLSAISQIKSSMTTLKSALDKVVSSADTNAYKASVPTDAGFTATTTSSAAPGNYSVEVVSLASAQKLASGAFTADATVGSGTLTIGYGDKSITVDISGTDKLADIAAAINKAAGGKGVTASVVTANDGQHLVFNAVDTGTKGALTVSASDPSLSALTFGAGVTGGLTQQVAAADALVRVDGFERTSSSNTVTDIVPGVVLNLTKAAEGTKVTLGVTADTSGLKGNLTAFAAAYNTANTLLKNSSSYNAETRTASALTGDSLVRGLQQQLRGQVSGSISELKALGLTIDKDGVMSFDGGKFDTAIAADGGAAAEALGKDSKFGSGLTKLLDANVNVNNGTLTLRSDSLNKQIKGFEADLDNLDARMEKLTDRYTAQFTAMETMISKMQGATGSLSSLLAIK
The following text describes a protein:
Function:
Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes.
Subcellular Localization:
Nucleus.
Sequence:
MLVCYSVLACESLWDLPCSIMGSPLGHFTWDKYLKETSSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSSEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIKIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPSPSSDVSTEKPSINSTKTVLEPQPGQRGRKPGKKRGRTPKILIPHPTSTPSKSAEPLKFPKKRGPKPGSKRRPRTLLSPPPTSPTTSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKSGSTGPHLDKKKIQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHVSLTATEYSHGHDRYLPGETFVLGNSLTRSLETHSDLMDSALKPANLVSTSQTLRTPGYRPLLPSCGLPLSTVSAVRRLCSRGVLKGTRERRDVESFWKLNHSPGSDRHLESRDPPRLSGRDPSSWTVEDVMQFVREADPQLGSHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSFHIDRLKQGKF
The following text describes a protein:
Function:
Required for correct axonal pathway formation in the optic lobe and for programmed cell death in the developing retina.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MLHTMQLLLLATIVGMVRSSPYTSYQNQRFAMEPQDQTAVVGARVTLPCRVINKQGTLQWTKDDFGLGTSRDLSGFERYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEAPKITQGDVIYATEDRKVEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVEHSQVRLECRADANPSDVRYRWFINDEPIIGGQKTEMVIRNVTRKFHDAIVKCEVQNSVGKSEDSETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTSTNLTFSVSNETAGRYYCKANVPGYAEISADAYVYLKGSPAIGSQRTQYGLVGDTARIECFASSVPRARHVSWTFNGQEISSESGHDYSILVDAVPGGVKSTLIIRDSQAYHYGKYNCTVVNDYGNDVAEIQLQAKKSVSLLMTIVGGISVVAFLLVLTILVVVYIKCKKRTKLPPADVISEHQITKNGGVSCKLEPGDRTSNYSDLKVDISGGYVPYGDYSTHYSPPPQYLTTCSTKSNGSSTIMQNNHQNQLQLQQQQQQSHHQHHTQTTTLPMTFLTNSSGGSLTGSIIGSREIRQDNGLPSLQSTTASVVSSSPNGSCSNQSTTAATTTTTHVVVPSSMALSVDPRYSAIYGNPYLRSSNSSLLPPPTAV
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MGERVILSSQGRLRPQLVLLGALDSVPMRLYGVSAFVHGDEMRRENKRRWTHEFTWFGVSHFSLYNGSSYTFTGGKSVIGAPCSQCAIASISPYVEQQSLLCVNQSLFLSALAAAIDCKDREEKGEEFQFLLHSLFLCVQMGEPNQGKTSQANLSKQTDGKPGSLMLTFSSKNPKHTELPNAKPKLDLSLGLSLGGVHREHFKEKPVIRSSSNAGMITEKVNTGEPNSAMQGVFLSFQRSCSLPVENKQREIMIKDLPAKKRIEAQRSLVEKQRKGGMAAIEKENPSAEKAVPPSPTYDVAAWAVASAARSPALCRAIGKIKAEGQIYGKRKLKDGLKDVAAAKVDTSSLSLPNPMETKPVFIPEATEKGKSVKLSKRKLKKPSKKVKVSKGCFQDNGMDVMKQMPSVTTTGDGPNALSLQPNSSSMPVERMSKTH
The following text describes a protein:
Function:
Sterol O-acyltransferase that catalyzes the formation of stery esters.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTPPMALYSRRNQQLDATTHDGKGKINAMDKIDAEPVPAQQSTQTRPCDTAHTLSKEQLAVGASTMASDSKSPKSPTKTTANSSHKPKSRIRKGSFRSRTSPLDYETLEREQNSMRGFFTLFWVFMAIYVVVTAYKNYRAEGIFISLRFYQQFSHDAIGLIVVDAAMILSLFVPFLAQAWLGGLGWSRGVWTIAMHVWQGVWFGVCLAIAFGKEWPWIQSGAFVGHCITMLFKQHSYSSYNIDLRFKHKQLLHLRQLLTEHKKDDDHDSTYPRTRSKTTEDASLTGTDAMIAEIADLEKELIKPNVSFPNNITLWNYIDYLLVPTLVYELSYPRTEKFRPLYFINKAAATLCTFGLLYVSYEHYILPVLLDMPNHTFFDSVFQLMMPFTMCYLLIFFIIFECICNAFAELTCFADREFYEDWWNSSTYDEFARKWNKPVHEFLLRHVYLESISTYKLSKTNATLMTFFLSSCVHELVMFVIGKKLRLYLFGLQMFQVPMIFIARIGWIKKQKLAGNVFFWFGMIFGPPLLAVTYMREHYA
The following text describes a protein:
Function:
Part of the L-tyrosine degradation gene cluster that mediates the biosynthesis of the brownish pigment pyomelanin as an alternative melanin. The 4-hydroxyphenylpyruvate dioxygenase hppD catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisic acid (HGA). The protein hmgX is crucial for this conversion and thus, probably functions as an accessory factor to mediate specific activity of hppD. The homogentisate 1,2-dioxygenase hmgA is then involved in the cleavage of the aromatic ring of HGA and its conversion to 4-maleylacetoacetate. When hmgA activity is lowered by the cell wall integrity (CWI) signaling pathway, HGA accumulates and leads to the production of pyomelanin through benzoquinone acetic acid after oxidation and polymerization. On the opposite, in non-stress conditions, both hppD and hmgA activities are balanced and HGA is degraded into 4-maleylacetoacetate. 4-maleylacetoacetate is further converted to 4-fumarylacetoacetate by the maleylacetoacetate isomerase maiA, which is degraded into fumarate and acetoacetate by the fumarylacetoacetase fahA (Probable).
Subcellular Localization:
Cytoplasm.
Sequence:
MASGTTIQPSRPSLTSNDSAVLQALFDAESSPSSAVAIDPSLSPFPEYLHISASDHESLKARELSIIRSLQSDDVSMDTITSAIRDLDALITEHPTYPSAYVNRAQALRLHIEKTAEASTDPEEAIFTPGNTESASRLFSDLGQAISLCTPRSPADPVSTVQARILADSHTHRGYLLLKAARLKKNANGNEMVGGPDKLRDMGPDQLEEMASRDFFFGGRYGNKVAQQLAVQTNPYAKMCGAIVKEALRKEVEGVI
The following text describes a protein:
Function:
Plays an essential role in chain termination during de novo fatty acid synthesis.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MLLRGTLPACNVAVSACNQPQKNNQLSHSFFNFTPRRQKSLLSASVARTSSIMAVATNEQKKEVAYEPSLADRLRLGSLTDDGLSYKEKFIVRCYEVGINKTATVETIANLLQEVGCNHAQSVGFSTDGFATTLTMRKLHLIWVTARMHIEVYKYPAWSDVVEIETWCQSEGRIGTRRDWILKDYATCEVIGRATSKWVMMNQDTRRLQKVTDDVHEEYLVFCPKEPSLMSIFASGKARISGRAHSGLSFASMRVPFFALPLPYTTKVDATFWSRCLSESSPTVSTLSPSLFLSSCVTTMTTSFPDGFANSSNTVQAFAQWRVVPRRADLDMNQHVNNVTYIGWVLESMPQDIIDTHELQSITLDYRRECQHDDVVDSLTSLESLEDAALGTNGSATASREINKSFLHMVRLSGDDGLEINRGRTEWRKKFVKS
The following text describes a protein:
Function:
Cell wall formation.
Subcellular Localization:
Cytoplasm.
Sequence:
MPVALPVTLYPDEPMARHSSWRAGGTARYYAEPATPDEAIALAAWAREQQLPLIWIGRGTNLLVRDEGFDGVIASYRGQRWELIEHGETAEVWIEAGAPMAGTARRLAAMGWAGLEWAEGLPGAVGGAIVGNAGCYGGSVAEVLITADLLLNGSECVEWSVHDLAYTYRESVLKQLLHTGIPPLVLAGRFRLQRGDPAALTARMKAIAAERKQKTPAGSSCGSVFKNPAGDFAGRLIEAAGLKGVRIGDAEISTLHANYIINRGQARAADILALIDLARTKVADQFGITLQLEVRII
The following text describes a protein:
Function:
Might phosphorylate lipids.
Miscellaneous:
MISCELLANEOUS: This bacteria makes up to 20 cubo-octahedral magnetosomes of about 45 nm in diameter which contain membrane-bound crystals of magnetite (Fe(3)O(4)); MISCELLANEOUS: Expression of just the minimal mamAB gene cluster (amb0961 to amb0978), including this gene, is sufficient to form a minimal magnetosome chain with small magnetite particles.
Subcellular Localization:
Cytoplasm. Note=Tagged protein forms a diffuse intracellular stain.
Sequence:
MRIAAIINERAGTVACLSPPVVAARLSAIWTSLGHQAHVTLAEGKDMGRAIRKACRDPAVHAVIIGGGDGSLSRSLKHVVGSGKSLGVLPLGTMNYVARQFGVPFDLDRAAVALADAVPTPTDLGRVNDRFFLIRACLGAFPEFIRSRDEARRKGGSFLDGALAGLTGLARGHRLIEAELIGPDVQARIATSFFMVSNNMCRDSDPFQLERERMDGATLGVYIGQGAGPFSLMDLGLQVAMGRWASNEALIRGSLPWLEIRTRQRKPLVSIDGEVEKMEAPFRFDILPGVLPMLVPK
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLVRYQVRNEYGLGDPEIYRSAKKDDSPALLEGVAVAGLVGILRQLGDLAEFAVEIFHDLHEQVMAVAARGHNMMIRLEYLEAEIPSVEKSILSKKTHIQCAYSKGSEWHTQIQIDQNHLTRGDLPRFIMDAYEECRGPPRLYLLDRFDTGGSGACLKRYSDPSFFKKKWVGSELMKAEKFQKEKKAHRNKKKAQHERNGEDRDVGSISQHNASSRCFSSLETNEKIARTERMSTPDMKLKPQQVNGSRSVELIKGTGSVRPIFGANSPPGLEEPETNLSATPSLKIRSFGRISTSTPSTLSLELNQMVAEDNRSSHESVHQESIHDSVMWEEKTEVLIPEVELAISSIDASESLLLSGLEERPSNYGNGVDQVMSPSGHEEGSGSQGQSDGTACETDTYMDARATMDSDTEMDPPCKKEGEMKLLSSLIQGFSPNGDSFRSLGSPMRTPPDDHEVPLGTGSACSHTPSNHDTSNSQYLACEGPTQTSASGFSENCISESFSDIVSVRLWTNGGLLGLEPAKPMNIGNAGNQAPNASAMVTTNNAECSSQDTDSTSMAHSTRAPLEEQTRNPGRLIECPYNFRPNMENRGNREDFVIKQKCQEDLALQLELKQGKSFKPSNNQLSNGSEENFVDASVVSSKAELQNSSSFEGKSSADHTEQSDDLVSKAHVKTNLVKFQGGSLRIDPATSSGNTNSKVLANDKFWSLQHSFSSKAGYNGPPSPPLEHMKISFHPMNGSSTSQFKLSFPDGHRFGGRIKDLSLCPSLSLSDPAVPLHDASETESALDLGVLSLKDQETQSKIFHGDSEVLKHADSEYDSEDYSTEEFHKRSPGFSVNLISQESESESWICDDTNGSKDERYDGLCRVSSDTSISSSLGLDGTSSLPFPEDCEFGGPYGGNGNRSPFSMSSSSVELLANLGTVNSTLVPESKDLRYSEPESSVNLASLQEISLNLAAPESIGYETETYEMPPPPPLPPVEWRTMKTPLPGLENKQETAIHASTIASMHTPDIKTVPQSEEGIAKGALMAALNSNGKSTLKKHEASVQPPRSEPLDERTMLLEQIRTKSFSLRRTTTARPNLSPGPTTNINVAAILEKANAIRQAFAGSDDGGDDDNWSDA
The following text describes a protein:
Function:
Plays a central role as a glucosyl donor in cellular metabolic pathways.
Sequence:
MTVFSGVNKIEFEGTFEGIGKDVVMSQMIRALQKHFPSIRDKNYEFSLFLHIFQRYVLENTSITHDLVCDKIRLPIIDEVVELDDIKNYGLLEGKLLSKLAILKLTGKANPIIGKESPLFEVKNGMSSLDVIVRQTQNLNVRYNSDVPLIFMTSLETESQVSNFLEEHYSSSKVRWKTVVQSSFPQIDKDRLLPIDLQINSHENDFWYPCGTGNLTDTLYFSGELDKLIAQGKEILFVSNVDNLGATGDLNILNFIINEKIEYLVEVVERTANVSNTGVLATYKGKLRSVYYNCLSNESASTCRIVNTNNIWIDLKKLKVLIESNSLNLPIHSSESKITHKNEEIECLQFKTQLVDCIAFFPNSRVLKVSRDRFLPLRTCKDLFLLKSTLYDLDSNGTFNLYPLKFGLLPSIDLGDEFATYETFKIGVPDIPNILELEHLTVMGNVFFGRNITLKGTVIIICDENDVITVPDGSILENVTIWHKSQLEDMNGY
The following text describes a protein:
Function:
Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSLETRSNSALFKRAEQLKRWEDSDTNREPVYPKQTSRKIKFSSGCVFLAACAAGDKDEVLRLLENGADINTANVDGLTALHQACIDDNSEMVEFLVEHGADVNRGDNEGWTPLHATASCGFLYIAKYLIEKGANVAAVNNDGELAVDIAECQKMEDLLNEEIKKRGIDCDAARNEEKRIMLQDAKEWLATKSTLVDAPHPKNGATALHVAAAKGYTDVMKILLQCGADIDAQDIDGWSPLHAAAHWGHKDACQILAENLADMDAKNYVGQTPFDLADNDMLKVLEDLKKKQNKEDVLNRRQAKKRAEIQDRTIETETPSKVKKVEVEAEKEDKEEDNIEMDVSSESESETESSSETESNSTDDEKKNRVNSLDAVSISNKPAEPTRLPPSVPPKQLVDSNNEDNAPSWRKQNTRQTKADLPSPVKTIADSVNNENDVTLRRPTSLQADKEFYSKYEELHARIKKYRNSNDIIPYSTRPHSDIIPNSYSTSQQHYRSLKEDSNENNSTSSTKTSPVMSPVSNNQPLRRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLEEIKSAEQFVKKKNQPNCNNNNNEQSGANGDSPNGVSVTATITTAAPTVITRDTEEPSITHERRPSWRLKIDSSSKFKLEDATKSSEPPSTPSFVRRTVTQNTTTNPRPSSAPVETAETTVTLPLRRPKTQDEKEQDKENDVRNAQATLATQAAIQRRRRPKRRSTGVVSFENMDDMDQDKDPSGGGDYEDSTKLNHEESDRSSRSRLGSTSDIRNENGEIDYKKLYEQALVENNELKDKLKKSDQELRDTKQTLEKLKVVTSKNSLSELEKRERRAMERKLSEMEEELKQLDIMKVENQKLKDENGALIRVISKLSK
The following text describes a protein:
Function:
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
Subcellular Localization:
Cytoplasm. Nucleus, nuclear pore complex.
Sequence:
MDEILSSFENLKISAFSKYSKLTGDINNVTIGPNSTILHDANEEEQKTPEPQKRQNLIEDKSPRSPPPLNQVLHVIETQRREKLQETIDDHYNKFEKFSKSRKEEKENQWYFKQQEFIQSMHDTEQMILQMLNQSDANKSKQNENLIKHYQDMAQRKMQYEQQLEKTKEKQRILNEHIEKIKKCQLEFRSVYQEIITIIKTCPSSDELKKSLGDSFKLLKILPESLDEVVAKCRNYNVDEEQFLRAVSIVNQVKNLKHEIEETVSRINHKKVEEPDKAAPLAQSTPVKVDPKTPVEKNDSIRTITDCVSVTNLKKYAEIKQFLSNHSQLYKDLLAEEQLKQFRFDCKKAINIPVNALSAVNSDHLRDKYVKLNNLLSGKTVIVADRQVNALKHPQGIPFCMDLLARKFVLQGDLMISSNPEAAFCYATIIVSLWNDFPDFGKLLLGYFYTECPYLVPFYIPKTEEQTTEEYYQVLGYHYIDGQIEKQDKFLKRMTGILRLYFAIFIAKPKRGQTKNPYDITNAWIFLASILKLKPQLDITATVLHVFLETVGFEMELVYGMAFKKLVVIIMEKFMPTLKKIDSGGPVTRLEVLLQDYKSKGHFETPNGILPNNFW
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MSVRIKYTSIIEAKTGLKSLGLSKKNILALGSGEEEDWLLLNEVNAQFNLHPIQIGKMEKRMISQLAWSPSGLYLATSNDKLIVWQFNGGNLSISRTYQGHKLEITALCWSPDDQRIATASLDGNIFIYHIKQDGIQHKIDCGQKTVGICWDPFDKYIVSLKFDNTVQIFKYKVNFYKIDNWKQEITVSLQIHGKQCTTKREDRKLDWSVDCRYLAVPNLDDKTIPTVAILDRNQNFQVVRTIIGPFSSINVVRFSPMLFKNIIAIGDNDGNISLWQINENQVDEQPFLLVKGHKKAGELIEDITWNQQGTVLMATTSKKYIIVIDFQLSLGQVLNETEKQQAIKSLYGDLKNTIKQIRFYQPKINNDNIKFADMQLENIDVQDELKNQIPDSAFQQREILKQTQTQFKQIIVDGKKKLIPLDVNSSEPVFKKVEQQQPLLIIQQYEILPKSYSFSMNNKSLLLEVQKQQQRIFNQAVYGTLIRCIENNTPKWIDYVEGQIKNIQYNDDLIVIYTDQALLYIENHKGMRQESPFILPFLSQIVLSPKNYILCLQNTGEFKVINLNTKTISYEGDIKILMQHVYEWMDQKQLFNEDEKKGKQSIDPLIKANLKIDTEGYPLVEFLFKDYCVYTYHKQLRQWIKTKQIDVNNQNQDIKNLKKFNFNQYQTPPYNDAQIYKRIIQKSTIEDAINDIQQISKLEEQLKIYWSDGDIKTYEKALYTYIKKLCDTWPNNQEKLSNIIETIITNYNSAEYKYLSERVQDMEELKKKIIYILQQFPQTRDLTLCLFPDHF
The following text describes a protein:
Function:
DNA polymerase II participates in chromosomal DNA replication.
Subcellular Localization:
Nucleus.
Domain:
The CysA-type zinc finger is required for PCNA-binding; The CysB motif binds 1 4Fe-4S cluster and is required for the formation of polymerase complexes.
Sequence:
MPSRKPSKYGNKFRSGAASFNPKRTKTVEFSSLRSSEATSQDEKFEAIRLANSIDESLGFPRFEAGEKRVGWLINMHSTSIEDPNVPGGRAGVDYYFLDDDGGSFKATVEYDPYFLIAVKTGHEAEVEEWCRRMFEGLIKKIKRVVKEDLKLPNHLLGHRRTFLQLDFANVSHLLEVRKTLLPLAEKNRKNARPNGTTNASDFIIDIREYDVPYHVRVAIDKDIRIGKWYTVEATHGIISLTCLEERLTRADPVVLAFDIETTKLPLKFPDSVIDQIMMISYMIDGQGFLITNREIVSEDIDDFEYTPKPEYSGPFMIFNEPNERAVIERFFEHIKEAKPTVIATYNGDFFDWPFVEARASVLGIDMYKEIGFRKNSEDIYQSDHCAHMDCFAWVNRDSYLPQGSRGLKAVTVAKLGYDPDELDPELMTPYASERPQTLAEYSVSDAVATYYLYMKYIHPFIFSLCTILPLNPDDTLRKGTGTLCEMLLMVQAYKGNIVLPNKHKDPPEAFYEGHLLESETYVGGHVESIEAGVFRSDIPVPFNIDPTAVDELLRDLDAALKFSIEVEEKKSLDDVTNYEEVKGQIAKLLTDLRENPHRNEVPFIYHLDVASMYPNIMITNRLQPDSLIQESNCAACDFNRPGKTCDRRLPWAWRGEFLPAKRDEYNMIRQAVQNERFPGRTKKSPMRAFTELSAEEQAAIVKKRLQDYSKKIYHKIHDSKTMVREAIICQRENPFYVDTVRSFRDRRYDFKGKQKVWKGKTESLKSSGAPAAEIEEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGVTCLTGARIIQMARELVERIGRPLELDTDGIWCMLPGTFPENFSFTLKNGKKLGISYPCVMLNHLVHGSYTNHQYQSLANPATFRYETHSENSIFFEVDGPYRAMILPTSKEEDKNLKKRYAVFNDDGSLAELKGFEVKRRGELKLIKIFQTQIFKFFLEGTTLAETYAAVARVADRWLDVLYEHGATLADEELIELISENRSMTKTLEEYGNQKSTSITTARRLAEFLGEQMVKDKGLNCKYIISARPRNTPVTERAIPVTIFSAEDSIKRHFLRKWLKDDPGDMDPRSVIDWDYYLERLGSVVQKLITIPAALQKIRNPVPRVAHPEWLQRRINKQDDRFKQVKMTDMFGKSEKNPLSDISTNIIDHRVQHADNLDEAMADSMEKLKSSSPQKASGKRKHPENQTKTSLDPFASLPAKMPSIDDDYVGFLKYQKQKWKIQKQARLRRRQLFGERANTGGDSLSHLFRNQAELLYISTWQVLQLAETSRPGIVRAFVLIDRKIHALTIKVPRCVYINLKQDSLPDVEVPECEVEKVNHTLPNGHPSVHLFKLTLSEETFLREADKIHVLLQHPSVEGVYERNIPLNLRAVLKLGSICTFDEAQRGVLGDGLERGFDLSTLCRTSSEQQYLQDSPLAYHFLYHVSSGEKQIFAIFSSTKNEAHIVILNRARDVQGLPNVDKIYSELLARKLQGQGDQAEGAFQYQEKIHFRTTQITTRRKAYLEVSDLIKKLRNDESLPAIMIIQSQQRSRLCHDIPILKEYPILSVKPEVSDMNLPPLGWQSFIAKRLVTHYLYLSSWVQHLTMLARYGDVPLCNLESDDPRFLIDISYARRLQQNNVVLWWSSTAKPDHAGYEKDDITGPLERVGMPCVNVPGSYTTVCVELEVRNLAINTILTSSIINEAEGADSLLAPSDPSAESSGSGVLYSEKAFASAGAVVLREMVKHWWSEACQGNNMADIMVQHLIRWVESPASCLYDRSLHQYVRMLSRKSFQQLMAEFRRVGSNVVFASPTRLLLQTSKTEVGNAYAYSQYVLKSIRANPSFHFIDLDIKEYWDYLVWYDEYNYGGKGCQEVAETEEQPLETVMHWQLSRFLPTPMQTIFHDWVVEYIELMHSFKRPESDDSSTPRLTQIPIGQPEPGQENEELSAALSDRFSKPLKKQISGLIRRQREELLHPELASDYVFPILPGVLTDPNEEKRNPVLELVKLLMQVLSLSKTTALETRLLRRELLALFEVREFSKEGRFENPGSSLKIPELTCSACCLIRDLDLCRDEDVLPERGSGSGPDSATSSRPWCCPFCQTEYDRLAQEEMLIGQVWGMVVAWQTQDLKCSKCGTLKISEFMEHCSCSGQWTETMNRADIEKRLKVLESVAKFHELKLLQVVVEEVLSQT
The following text describes a protein:
Function:
Single-stranded DNA endonuclease activity in vitro. May not be active as double-stranded DNA endonuclease. Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA with a specific cleavage site in the 5' overhang strand exactly one nucleotide 3' of the branch point (By similarity). Structure- and sequence-specific nuclease that resolves holliday junctions (HJs) by symmetrically oriented incisions in two opposing strands near the junction point, thus leading to ligatable products; HJs are physical links between homologous DNA molecules that arise as central intermediary structures during homologous recombination and repair in meiotic and somatic cells (By similarity). Probably involved in the resolution of toxic replication structures to ensure genome stability, and to maintain telomere integrity and replication (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MGVKNLWDILESCKKKLPLHHLQNKKVCVDLSCWLVQMYSANRSPAFAKDKVYLKNLFHRIRALLALNCTLLFVTDGAIPSLKLATYRRRLGSISHAAKESDQPNSHPSISLRRNKGSEFSCMIKEAKRLGMALGIPCLDGLEEAEAQCASLDLESLCDGCFTSDSDAFLFGARTVYRDVFIGEGGYVICYEMEDIEKTLGFGRNSLISLAVLLGSDYSNGVNGFGPETACRLVKSVGDNLILDQILSNGVKATRKCKGKNSGNKVDDMCPKASSCEVGMTQDSDGQFRDVINAYLEPKCHSPDSEAVQRVCGQHPFLRPQLQKICEEYFDWSPEKTDQYILPKIAERELRRFSDLRSASSALGIKPLLSEIPVPCPVLAIVKQRKVHGNECYEVSWRNIEGLQVSVVPGDLVKSACPEKITEFLEKKGEEKKQKRRARPKKSGQAAVKDVDEQLQELLLGIEADSGGILGATASVCQTLTAAYTVAVEDVVDLSSPSPPLRKLSKSQKKMMAEDVNVAGMNMNKMESESSFSTQSSTSDVDNQLIDLSSPLAGGDNGMKGGRRALADISNVGSHSTETDGGGGGGGGVASVGHGTTIDLSSPSPAIGDRSRVHHDDDDVIHERKARDLRMFLDSIRNELY
The following text describes a protein:
Function:
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation (Probable). Directly recognizes five C4-dicarboxylic acids: L-malic, citramalic, citraconic, bromosuccinic and methylsuccinic acids. Three of the identified ligands act as chemoattractants (L-malic, D,L-bromosuccinic and L-citramalic acids) whereas two of them (L-methylsuccinic and citraconic acids) behave as antagonists by inhibiting the downstream chemotaxis signaling cascade. Antagonists compete with chemoattractants, thereby decreasing the affinity for chemoattractants and the subsequent chemotactic response. Acts through the che chemosensory pathway.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MMRLTLKSKVLLLAMVPVLLFALVLSGGAVLILKKQADAEVKDTRERLLGDRRAELEHYVQIAMGSIQAEYDRSANGDLNARAEAIARLSKIKYGKDGYIFGYDSQVVRLFRGDSPVDVGKSFRDRRDPSGVYLNRELVEAGRNGSHYVTYTSPLPGNESVMVPKLSYTLYLPKWDMVIGSAINLDGVEAQLVEIKQDIDERIGTLIASIVGIAGVLLVVLLVIGLAVANAMLRPLHQIRQNLDDIAAGEGDLTRRLPVTSYDELGELAGSFNRFVEKIHGLVRQIAGMTGDLKQLVEQMSAQAERSEQAMERQRHETDQVATAINEMSAAAHEVAQSAQRAAEAAQQTDHEGQAAKRVVDGSIERIHALVDEIRDSGTSLDSLQQDVQSIVSVLGVIRSIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRALASRTQQSTQEIQGMIDRLQQGTNAAVDAMRRSGEAGEGTSNQANQAGDSLDAIAQLIATINAMNAQIASAAEEQTAVAEEINRSVHQIAGAVDSVADEAQQGAQTARSLAQLGQGLGRLVGQFRI
The following text describes a protein:
Function:
Possesses antifungal activity against B.cinerea, M.arachidicola, F.oxysporum, R.solani and C.comatus; Suppresses the activity of HIV-1 reverse transcriptase and stimulates the proliferation of murine splenocytes.
Sequence:
NEYHGFVDKANNENKRKKQQGRDDFVVKPNNFANRRRKDDYNENYYDDVDAADVV
The following text describes a protein:
Function:
Processive microtubule plus-end directed motor protein involved in neuronal axon guidance. Is recruited by KANK1 to cortical microtubule stabilizing complexes (CMSCs) at focal adhesions (FAs) rims where it promotes microtubule capture and stability. Controls microtubule polymerization rate at axonal growth cones and suppresses microtubule growth without inducing microtubule disassembly once it reaches the cell cortex.
Subcellular Localization:
Cell projection, axon. Cell projection, dendrite. Cell projection, growth cone. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Sequence:
MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEEQGIISRAVKHLFKSIEEKKHIAIKNGLPPPDFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDADSATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKRLQKLEESNREERSVAGKEDNTDTDQEKKEEKGASERENNELELEESQDMSDHEDEEEEEEEEEDDIEGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTSSSAAALETDASRTGVQQKMRIPVARVQALPTPTTNGTRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLIANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKSKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSPPPGLPSKIGSISRQSSLPEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDTASN
The following text describes a protein:
Function:
Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).
Domain:
Composed of 3 domains: the N-terminal domain has structural similarity to S-adenosylmethionine decarboxylase, the central domain is made up of four beta strands and the C-terminal domain is similar in structure to spermidine synthase. The N- and C-terminal domains are both required for activity.
Sequence:
MAAARHSTLDFMLGAKADGETILKGLQSIFQEQGMTESVHTWQDHGYLATYINKNGSFANLRIYPHGLVLLDLQSYDGDAQGKEVDSLLNKVEERMKELSQDSTERVKRLPPIVRGGAIDRYWPTADGRLVEYDIDKVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIMGSGKEDYSGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWKKAKP