lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Gap class segmentation protein that controls development of head structures.
Subcellular Localization:
Nucleus.
Sequence:
MESVEEPPCTCQVCGFVIPPSQLSHHYEKCHNSREFNCDRNPPEAYFCTYCNYHTPFKVTLYHHVKQTHISRTDSLDCNFKTHTCSVCKFQTSSIVFLLKHGLENDECGQVLDKSFRCNQCNYKSLRKATLKRHVQIVHATGDPRLHPCSFCPYRAHTKSTLKDHIKFRHTPPEDIQWFKCEFCLHQSKSNRELKAHFVTKHAAPDQVTWHQCSQCDYKTKQKQLLRSHTYYNHTASDEIKWFRCEHCEYQTKYKHNLRLHVTRRHPAALNVTQQWFKCEQCDFKARTNFHLMDHINVQHSAGDDKSLMCDLCSFKTNHKYYMDRHKSTHEIKWHQCQKCDYKTRVKMCLSQHIYNKHTELEVKYYQCEFCSYKTRNGAKLQPHVVENHSDSKEVFFKCEHCNYKTKLKGLMKSHTIRKHAPPDEIKWFSCEQCDYKARIKFNLTQHIKSHHSNVKEFGCPLCAFKTNRKYYLKRHHLLIHARPDEIKWVKCDYCDYMSKESRRLKGHIKSKHSGVENKDVKWFRCDKCDFITKRQRVLERHESNKHGN
The following text describes a protein:
Function:
Required for maintaining the appropriate mycolic acid composition and permeability of the envelope on its exposure to acidic pH.
Sequence:
MKTTAAVLFEAGKPFELMELDLDGPGPGEVLVKYTAAGLCHSDLHLTDGDLPPRFPIVGGHEGSGVIEEVGAGVTRVKPGDHVVCSFIPNCGTCRYCCTGRQNLCDMGATILEGCMPDGSFRFHSQGTDFGAMCMLGTFAERATVSQHSVVKVDDWLPLETAVLVGCGVPSGWGTAVNAGNLRAGDTAVIYGVGGLGINAVQGATAAGCKYVVVVDPVAFKRETALKFGATHAFADAASAAAKVDELTWGQGADAALILVGTVDDEVVSAATAVIGKGGTVVITGLADPAKLTVHVSGTDLTLHEKTIKGSLFGSCNPQYDIVRLLRLYDAGQLMLDELVTTTYNLEQVNQGYQDLRDGKNIRGVIVH
The following text describes a protein:
Function:
Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MAEKGAVGGGGPAGGITPLQQILASGTGAIVTSIFMTPLDVVKVRLQSQRSAPTQELASPQGPWTLRYGKWRCFLYCNGILELPYVCQNGGRCATWYPAPTHFTGTVDAFVKIIRQEGARTLWSGLPPTLVMAVPATAIYFTTYDQLRSFLSHHGATSDLYAPLVAGAVARLGTVTVVSPLELVRTKLQSQALTYQELRVSIRGAVAQGGWRSLWQGWGPTVLRDVPFSALYWFNYELVKRRLEDWMQSDRASVSISFLAGALSGTVAAALTLPFDVVKTHRQIDLGKVETLRVTSPRSPSTWLLLRKIRVESGTRGLFAGWSETCSWGWKPKSRTAPAWTASGPSLGRGATGVSLGPGRPPPPPGTHRDQRAGGAARARDGSWGAGGGLVSSPWELVFVLLCSPMRSVQCSAPSKRSIINRYLLSAYWEPSTVLSAWESTTELAEMFPAQNEISKYH
The following text describes a protein:
Function:
Has a broad role in development, specifically in the genetic pathway SynMuvB that negatively regulates specification of the vulval cell fate. Required for fem-3 3'-UTR-mediated repression in the regulation of the sperm/oocyte switch. Acts by regulating the translation of fem-3 mRNA, by binding to its 3'-UTR.
Subcellular Localization:
Nucleus.
Sequence:
MFHALSGASLAAMKEGKEESSAPEDEPNGVPDEGRLPEFLRGHVEIGTYVPVAMPKAGDFRMDESEALLEAPSLVTPLLIKRPDQFASRGERKRSPRPAPLAKGGNSVADFFGSSAGEFLIGLGLSRALEVFNRDMMRLKEREMKKAGGRTPELVAEHQRLAEAYQQAKAANAPYTFRVKPCRVCDFKTESSLVLEGHLLTPHFTSRRELQCSFCNFVTRDAKAIVFHMEAIHNRLPTMESPPQFYECPFCPFETNLKTKASGHVNRCQKYFNNGMNQLPAGDFQPPGVTAKPITVDDIKTYEKFFLALGGGTAKARTYTALSRNGAPVAGPRPLYQQLASAAALGRGRGRPRLALIQPAPTSGQVFQVLGGGSEVVPLLNGSPQLTVTLARAPAPANGSGRLAPRAPPAAAGQRARTPVILESSGSGQAFVICEICDGYIKDLEQLRTHMQWIHKVKIHPKMLASRPPLNCQKCQWRFFTDQGLERHLLGAHGLVTSNMQDLANSGQDGGRCTVCGRIYASKLVAHMSQVHRVVLKPAHLSYKCTVCTATFNLYKLFETHVYTVHSGAMKRSAPAAAPDERPPKRPAEARPAETRLERCAACGLDVADLGAHLKEQHVRPCRVRVCHIEKCDRCLCSFDGMIVLHTSDFGDSSDEEEDAPEGPPASSE
The following text describes a protein:
Function:
Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, cilium axoneme.
Sequence:
MATGEPRDRGGYYFRFLPQRTFSSLSAREITNRLRQWSMLGRIQAQAFGFDQTFQPYQKDDFVTAFFKDPNVIPHLQLLAESSGQWTTLGTEVKRIEAINVPCTQLSMSFFQRLYDENIVRESGHIVKCLDSFCDPFLISDELRKVLLMEDSEKYEVFSPVEREEFLFCLFKHLCLGGSLCQYEDVLKPYLETAKLIYKDLVSVRKHPRTKEIQITSSVFKVKAYDSLGVCYPSPKEHEQTFSYFVVDPIKRHVNVLYHCYGVGEMA
The following text describes a protein:
Function:
May only reduce GSH-thiol disulfides, but not protein disulfides (Probable). Participates probably to the maturation of iron-sulfur proteins and to the regulation of the redox state of the BOLA proteins. The GRXS17-BOLA2 heterodimer binds a labile, oxygen sensitive iron-sulfur cluster.
Subcellular Localization:
Cytoplasm.
Domain:
The Glutaredoxin 2 domain is sufficient for interaction with all BOLA.
Sequence:
MSGTVKDIVSKAELDNLRQSGAPVVLHFWASWCDASKQMDQVFSHLATDFPRAHFFRVEAEEHPEISEAYSVAAVPYFVFFKDGKTVDTLEGADPSSLANKVGKVAGSSTSAEPAAPASLGLAAGPTILETVKENAKASLQDRAQPVSTADALKSRLEKLTNSHPVMLFMKGIPEEPRCGFSRKVVDILKEVNVDFGSFDILSDNEVREGLKKFSNWPTFPQLYCNGELLGGADIAIAMHESGELKDAFKDLGITTVGSKESQDEAGKGGGVSSGNTGLSETLRARLEGLVNSKPVMLFMKGRPEEPKCGFSGKVVEILNQEKIEFGSFDILLDDEVRQGLKVYSNWSSYPQLYVKGELMGGSDIVLEMQKSGELKKVLTEKGITGEQSLEDRLKALINSSEVMLFMKGSPDEPKCGFSSKVVKALRGENVSFGSFDILTDEEVRQGIKNFSNWPTFPQLYYKGELIGGCDIIMELSESGDLKATLSE
The following text describes a protein:
Function:
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MRQFVVLGHDAPTTPDFPLDDLPGAAGRLDVLCRCVSAALFVSHGIRDDVEVFLVLGDEVTVRIDAGAVQYMHPDERNVAGLLKQALDAKTEAIGHQEASSSPGIHVSKRGFEAVLDAVSGPVVALHEDGDALAAVDPLADPVFVLSDHRDFTAAEASLLADASDHRVRVGPTVLHADHAITVAHNHLDTAGFDAY
The following text describes a protein:
Function:
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code; Histone demethylase that specifically demethylates both mono- and dimethylated 'Lys-9' of histone H3. May act as a transcription regulator controlling hair biology (via targeting of collagens), neural activity, and cell cycle.
Subcellular Localization:
Nucleus.
Domain:
Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors; The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.
Sequence:
MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSWLLPGFPQGPKDMLPLVEGEGPQNGERKVNLLGSKEGLRWKEAMLTHPLAFCGPACPPRCGPLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPERPCDWPLTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNPGGHLQRAREAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPRTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGNPAPKRPPDPFPGTAEQGAGSWQEVRDTSIGNKEVDSGQHDEQKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGEPQQEEDTAANSSSEEGPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGHVAGTGGAREKAGFQEQSTEECTQEAGHAACSLTLTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQPSCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAFAPVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLPPPGALLWLQEPRPWPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQALSPLGPPQPTSLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLPEYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHADAPLPAWHRAQKDFLSGLDGEGLWSPGSQVSTVWHVFRAQDAQRIRRFLQMVCPAGAGALEPGAPGSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFLSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK
The following text describes a protein:
Function:
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MAGLELLSDEQFRADGRRPNEIRRVRCKMGVFKQADGSAYLEQGDTKVLAAVYGPHEAKSGKNKPMHDQAIVNCQYSMAVFSTTERKQRPRGDRKSTEIGQNLKQTFESAILTHLYPKSQINIYIEILQADGSNLAASINAATLALVDAGIPMKGLVCCCSAGNVDDTPLIDLNHVEESQGDLKLTIAMLPLTEQILMLNMNGRLHEERLEKVMSSAKNGCKEILKDLSQAVRDQQLDLVTGS
The following text describes a protein:
Function:
Major component of the type IV pilus (T4P) that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility facilitated by cycles of extension, adhesion, and retraction of T4P fibers. In addition, plays a critical role in type II secretion of exoenzymes by interacting with specific components such as XcpT or XcpU. Modulates host calcium signaling through interaction with host calcium-modulating cyclophilin ligand.
Subcellular Localization:
Fimbrium. Cell inner membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane. Note=Likely secreted through the outer membrane PilQ secretin channel for surface display.
Domain:
PilA subunits constituting the T4P exhibit a classical pilin fold featuring an extended N-terminal alpha-helix linked to a C-terminal globular beta-sheet-containing domain, which are packed tightly along the pilus. The N-terminal helices constitute the pilus core where they stabilize the tubular assembly via hydrophobic interactions. The alpha-helical core of the pilus is surrounded by the C-terminal globular domain of PilA that coats the outer surface of the pilus, mediating interactions with the surrounding environment.
Sequence:
MKAQKGFTLIELMIVVAIIGILAAIAIPQYQNYVARSEGASALATINPLKTTVEESLSRGIAGSKIKIGTTASTATETYVGVEPDANKLGVIAVAIEDSGAGDITFTFQTGTSSPKNATKVITLNRTADGVWACKSTQDPMFTPKGCDN
The following text describes a protein:
Function:
Catalyzes the reaction of 4-carboxy-5-aminoimidazole ribotide (CAIR) and aspartic acid with the formation of N-succinyl-5-amino-imidazole-4-carboxamide ribotide (SAICAR) in the purine biosynthesis pathway.
Miscellaneous:
MISCELLANEOUS: Present with 4280 molecules/cell in log phase SD medium.
Sequence:
MSITKTELDGILPLVARGKVRDIYEVDAGTLLFVATDRISAYDVIMENSIPEKGILLTKLSEFWFKFLSNDVRNHLVDIAPGKTIFDYLPAKLSEPKYKTQLEDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQGLKESQEFPEPIFTPSTKAEQGEHDENISPAQAAELVGEDLSRRVAELAVKLYSKCKDYAKEKGIIIADTKFEFGIDEKTNEIILVDEVLTPDSSRFWNGASYKVGESQDSYDKQFLRDWLTANKLNGVNGVKMPQDIVDRTRAKYIEAYETLTGSKWSH
The following text describes a protein:
Function:
Metalloendopeptidase that acts selectively on DNA-binding proteins. DNA is needed to bring the protease and substrates together to enable proteolysis. Involved in the repair of toxic DNA-protein cross-links (DPCs) such as covalently trapped topoisomerase 1 (TOP1) adducts on DNA lesions or DPCs induced by reactive compounds such as formaldehyde.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MELKFSCRGNVIALSFNENDTVLDAKEKLGQEIDVSPSLIKLLYKGNLSDDSHLQDVVKNESKIMCLIRQDKDIVNQAISQLKVPDYSTNTYSLKPKKPHTTPKPASIYTFNELVVLDYPHKDRALRYLERLRDDTGIKKIMDSHRWTVPLLSEMDPAEHTRHDSKTLGLNHNQGAHIELRLRTDRYDGFRDYKTVKSTLIHELTHNVHGEHDSSFWELFRQLTKEADAADLLGKPGSYVSDRASYTPQQDNDDEDQKNHRRDLLLAAAERRKQSGSKVQKE
The following text describes a protein:
Function:
May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway. Negatively regulates KIN10 leading to a repression of the SnRK1 signaling pathway.
Subcellular Localization:
Cytoplasm. Nucleus. Endoplasmic reticulum. Note=Co-localized with ER marker when associated with KIN11.
Sequence:
MSQHSNYQMTTASDYYSTKPVLSAIRSHKLISSVFEGKCPSDYESAWSPTSPLDFRLFSTLGNPFAASSSRSIWRGKQRSWDSGKVGLSIVHSLVDDHHTDSSATIVLPSPDSKNIIFGSLMRSGQKPHLLSQPFTKALMPKDVIPNAVFEIGHDVIDVLELRKSGSVDAAYCSGAENFSVNNNACQVTKQDPGSLNGGTESDMEISEDYTCVISHGPNPKTTHFYGDQVMESVEREELKNRCCKNEKESIFAVAPLDLTTPVDVLPPKDFLSFCYGCSKKLGMGEDIYMYSGYKAFCSSECRSKEIDLDEEMEDGDEEEAIKSVSSSDKESKKKSNGVFFTVG
The following text describes a protein:
Function:
Probable ATP-binding RNA helicase which may be involved in ribosome biogenesis.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MTTINYNENINNNNNTLESFGIEEWLINNLKEQSIINLFPVQQEIVPFINRTEGHDICVCAPTGSGKTLAYAIPLVQKIVKRVVRRVRVAVIVPTHDLVIQVEKTFQSIIKGTDLVVLSLGVKPFHIEQKLLIKNHSYGEHALYESLVDIIVSTPGRIVDHINETLGFTLKYLNYLVIDEADRLLRQSFQDWLEIVIDSTNQHSDLNQQQEEQLIKYNSKGDIELFEKSISLKDNNNQMNHLCWSEFKLVKLLLSATMTYNPSKISLLQLNAPLFFTTSKTKEIKYSMPSTLKECYIISNGDQKPLVLLNIIYESLLKNNANGENKKKIICFTKSVDITHRLNTLLKLIGQVDKLKFTCEEYSSSLSTVERADLLSRFKLNQIDILICSDIMSRGMDIQDIDVVINYNTPPNITLYVHRVGRTARAGNFGVSYTIVDKSEIKYYISMMKKAERSQTLHCLKWKPNVYEKFQSSYKLGLNQMRLIYSKRKINDIGDNGDDNNDNNNEDGNEIDGSVENIENNNNNNNNNNKNNNNNNFEKDYEVKLKHSLLEISKKKAKINFNI
The following text describes a protein:
Function:
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
Subcellular Localization:
Nucleus. Chromosome. Note=Associates with chromatin.
Sequence:
MWEPYMPVEPGLGREENFLSLEDLLMSQEKLPCCIESGFPRLGFLDKGGDSDSIPEGSKMELPLWLAKGLYDNKRRVLSVELPKIYREGWRTVFSADANVVDLHKMGPHYYGFGSQLLNFDSPENPEIAKTILQTFVGRFRRIMDSSQNAYNEDTSGLVARLDELERSLFRAGQRGLNAFQSWERGKAAQITASNLVQNYKKRKFNEADA
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MTEPVFLFGSFTEDEAQQLQASVPESPSPKGSHRSLKPALKENGFHSAHNHPSELKIAPKAAPSKVAAAAQNGLSPAPKSVSKPNSSIVGNGKQPESANAPSRIAGRGVKKQVLSPAVGLGPQKGGKQVDAKSSAANNHIAENPLKRIVNNGAADLGYHAGRTPSSSQDFSVANGQGPPRAVVTPLNQNGTVSGKLGTKEEAVITSSVSSQLAIAPKSILGSDENSAKSSQGKEGSDLVRIRTTSDSESDGVASEFMPKSWAALVSVPTDSADMDGASGSLRRKPKDAQKRQPVSPQSQVPAVTVLSGDIWLKSLRKADTAGRRLLPRGLVNTGNSCFLNSTMQAMLSCPAFTHLLQVLKDRTVPQHGYPTLQAFLNFFGEFEPLPDTNALKVRREVDGKVPAVEVGRPFVPAMFDGILQSFTPDQPLRAKGRNRQEDAQEFLSFVMDRMHEEILRLQGNDSPVSQSSPSGPSFEDGDWEMVGPKNRTSVTRTHQFSESAVTDIFGGQLRSVVKTKGNKASATVQPFMVLHLDIVPEFVHSVEDALRMFAAPESLEGYKPATAKVGEVVAASKSVKIQTLPRVLILHLMRFSYGSSGSSKLHKPVQFPLEVTLGRELLASSTGSGNESRRYELVATVSHHGKDPSVGHYTTDSKQASGQWLRFDDGAVSAISVNRVQQEQVYVLFYKRLGV
The following text describes a protein:
Function:
Required for the establishment of systemic acquired resistance (SAR). Not involved in local defense mechanisms. Confers a salicylic acid-dependent (SA) resistance to virulent pathogens such as P.syringae pv tomato and H.parasitica.
Sequence:
MASNYDKLTSSRVAIIGAGVSGLAAAKNLVHHNPTVFEASDSVGGVWRSCTYETTKLQSARVDYEFSDFPWPNNRDDTTFPPYLEILDYLESYAKHFDLLKFMKFGSKVIEVRFIGDGETPQMVDLGAYGNLLPGKPVWEVAVQIGDSGDIQWHAFEFVVVCTGKYGDVPRIPAFPAKKGPEMFQGKVMHSMDYCKLEKEEASTLLSGKKVAVIGFKKSAIDLALESALANQGEGGKACTMVVRTTHWGIPHYWVWGLPFFLFYSSRASQFLHDRPNQSFLRTLFCLLFSLLRAVVSKFIESYVLWKLPLEKYGLKPNHSFEEDYASCQMAIIPENFFEEADKGMIRFKKSSKWWFYEEGIVFEDGTTLEADVVILATGYDGKKKLKAIVPEPFRTWLEFPSGVMPLYRGTIHPLIPNMGFVGYVQSSSNLHTSELRSMWLSRLVDEKFRLPSKEKMLDQFLKEMEVTRNSSRFYKRHCISTFSIQHADDMCNDMGLNPWRKSNFLLEAFSPYGSQDYRLGQEEKEDMTA
The following text describes a protein:
Function:
Required for pollen development. Probably synthesized in the tapetum, packaged in Ubisch bodies and transported at appropriate stages to the micropsores.
Sequence:
MARFLLLLVAVAAAAAVLSLGDAAPSTAEVFWRAVLPESPLPDAFLRLLRPDTSFVVGKAEAAGGAARTGFPFDYTDYRGSDSPTTASGLDLAGDFGEPAPFGYDYSAQGEGGGGGAAAAAGEQVLAVDAGFNYDKYVGARKLRGGSSTAGGENDDEPFGYDYKAPSSGSGTAASTTARGVGTGATTTVFFHEEAVRVGERLPFYFPAATTSALGFLPRRVADSIPFTAAALPAVLALFGVAPDTAEAAGMRETLRTCEWPTLAGESKFCATSLEALVEGAMAALGTRDIAALASTLPRGGAPLQAYAVRAVLPVEGAGFVACHDQAYPYTVYRCHTTGPARAYMVEMEGDGGGDGGEAVTVATVCHTNTSRWNPEHVSFKLLGTKPGGSPVCHLMPYGHIVWAKNVKSSTA
The following text describes a protein:
Function:
Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MRRGFGPLSLAFFLFLLALLTLPGDGNQGSVAGSCSCDRTISSGTQIPQGTLDHIRKYLKAFHRCPFFIRFQLQSKSVCGGSQDQWVRELVDCFERKECGTGHGKSFHHQKHLPQASTQTPEAAEGTPSDTSTPAHSQSTQHSTLPSGALSLNKEHTQPWEMTTLPSGYGLEARPEAEANEKQQDDRQQEAPGAGASTPAWVPVLSLLAIVFFLTAAMAYVLCNRRATQQNSAGLQLWYTPVEPRP
The following text describes a protein:
Function:
Anther-specific aspartic protease involved in tapetal programmed cell death (PCD). Directly regulated by the transcription factor EAT1/DTD in anthers during tapetum PCD and degeneration.
Sequence:
MAATTTIPLLLLLLAATVAAAAAELSVYHNVHPSSPSPLESIIALARDDDARLLFLSSKAATAGVSSAPVASGQAPPSYVVRAGLGSPSQQLLLALDTSADATWAHCSPCGTCPSSSLFAPANSSSYASLPCSSSWCPLFQGQACPAPQGGGDAAPPPATLPTCAFSKPFADASFQAALASDTLRLGKDAIPNYTFGCVSSVTGPTTNMPRQGLLGLGRGPMALLSQAGSLYNGVFSYCLPSYRSYYFSGSLRLGAGGGQPRSVRYTPMLRNPHRSSLYYVNVTGLSVGHAWVKVPAGSFAFDAATGAGTVVDSGTVITRWTAPVYAALREEFRRQVAAPSGYTSLGAFDTCFNTDEVAAGGAPAVTVHMDGGVDLALPMENTLIHSSATPLACLAMAEAPQNVNSVVNVIANLQQQNIRVVFDVANSRVGFAKESCN
The following text describes a protein:
Function:
Anther-specific aspartic protease involved in tapetal programmed cell death (PCD). Directly regulated by the transcription factor EAT1/DTD in anthers during tapetum PCD and degeneration.
Sequence:
MNAAVLLLLLALAALPASCAPPRSFRLELASVDASAADAANLTEHELLRRAIQRSRYRLAGIGMARGEAASARKAVVAETPIMPAGGEYLVKLGIGTPPYKFTAAIDTASDLIWTQCQPCTGCYHQVDPMFNPRVSSTYAALPCSSDTCDELDVHRCGHDDDESCQYTYTYSGNATTEGTLAVDKLVIGEDAFRGVAFGCSTSSTGGAPPPQASGVVGLGRGPLSLVSQLSVRRFAYCLPPPASRIPGKLVLGADADAARNATNRIAVPMRRDPRYPSYYYLNLDGLLIGDRAMSLPPTTTTTATATATAPAPAPTPSPNATAVAVGDANRYGMIIDIASTITFLEASLYDELVNDLEVEIRLPRGTGSSLGLDLCFILPDGVAFDRVYVPAVALAFDGRWLRLDKARLFAEDRESGMMCLMVGRAEAGSVSILGNFQQQNMQVLYNLRRGRVTFVQSPCGALR
The following text describes a protein:
Function:
Involved in the presentation of foreign antigens to the immune system.
Subcellular Localization:
Secreted.
Sequence:
MVRMVPVLLSLLLLLGPAVPQENQDGHYSLTYIYTGLSKHVEDIPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPLQDTAPYSCHVQHSSLAQPLVVPWEAS
The following text describes a protein:
Function:
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Sequence:
MASSLPLLPKPISPFFKTPPFSTSKPLVFLNFQTRLTSRSSDVSVNLKKKNNPWLDPFDSGEDPDNEYGSLFADGKQDEDPRPPDNPDNPYGFLKFPKGYTVELASLPLKIRGDVRRCCCVISGGVYENLLFFPTIQLIKDRYPGVQVDILTTERGKQTYELNKNVRWANVYDPDDHWPEPAEYTDMIGLLKGRYYDMVLSTKLAGLGHAAFLFMTTARDRVSYIYPNVNSAGAGLMLSETFTAENTNLSELGYSMYTQMEDWLGRPFRSVPRTPLLPLRVSISRKVKEVVAAKYRNAGAVTGKFIVIHGIESDSKASMQSKGDADSLLSLEKWAKIIKGVRGFKPVFVIPHEKERENVEDFVGDDTSIVFITTPGQLAALINDSAGVIATNTAAIQLANARDKPCIGLFSSEEKGKLFVPYAEEKSNCVIIASKTGKLADIDIGTVKNAMQVFEGSLALV
The following text describes a protein:
Function:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
Sequence:
MATLRGSAIVSPMWRTHTVTRPRLHLGTCYKACARPGLLTTTIRYVRYSTATPQQQTLARKIERGVSKLFRDADEAVSDLKSGSTILSSGFGLCGVADTLLSAINRRGVENLHSLTAVSNNAGAPGRGGLSTLTQAGQVDRLILSYLGNNKALEKKYLTGKIAIELCPQGTLAERLRAGGAGIPAFFTPTGAHTLLQAGEIPVRLDESGKVLERGTPRETRIFNGKTYLMETALTGDVAILRAWKADEAGNCVFRYTTKAFGPVMAKAATLTIVEAENIVPVGSIDPNDVDLPGIFVDRVVPATAEKHIEIRKLRTPENEDATKTLSDPAMAQRNRIARRAAKELKQGYYVNLGVGIPTLAPSFLPEGTKVWVQSENGILGMGPYPTEDEVDPDIINAGKETVTLMPGAATFDSTESFGMIRGGHVDVSILGVSEADYACERIEYRANDKQALQVSAKGDLANYMIPGKVFKGMGGAMDLISNPDQTKIVVATSHTAKDGSPKVVAECSLPLTGANCVSTIITELG
The following text describes a protein:
Function:
Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MSGSSDGPEDKQEWRHKDIPRFVVGCEEDEEDDDMDQVEIDMKSDNSREEDMEEDDDSVRQIVVGICSMMKKSKSKPMTQILERLCKFEYIDVVIFSEEVILEEPVEKWPHCDCLISFHSRGFPLDKAVEYAKLRNPLLINDLNMQYFIQDRREVYRILKEEFIELPRYAVLNRDHPEECNLVEGEDHVEVNGEVFPKPFVEKPVCAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESSVRQTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAFEKLVARKVCLAFKQTVCGFDLLRANGHSFVCDVNGFSFVKSSMKYYDDCAKILGNMIMRELAPKYSIPWSIPIEDEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMESQINKAALPRKCEGYFLLDIARQLLVELGQHTDCEIEEKKSKLEQLKTVLEMYGHFSGINRKVQLTYMRKGKPKTSSEEEDCKKDGPSLLLILKWGGELTPAGRVQAEELGRAFRCMYPGGQGDFAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLTDCQQKVKARLHEIMQKDQEFMQEDYHKLAPTGSPSLVNSMNIIENPVKTCDKVYTLIQSLTSQIRKRLEDPKSADLQLYHSETLELMLQRWSKLERDFRMKNGRYDISKIPDIYDCIKYDSQHNASLSLEDTMELFRLSRALADIVIPQEYGISKAEKLDIAQAYCVPLMKKIQLDLKRTHEDEAVNKLHPQYSRGVMSPGRHVRTRLYFTSESHVHSLLNMFRYGGLLNEENDQQWKQAMEYLSAVNELNYMTQIVIMLYEDNNKDLTSDERFHVEFHFSPGVKGCDDEENVPLGFGFRPASSENEDKKTNQGSLECLSEDQTDRALLVSDPINIQRKSPVIRNRKTGSMEVAHFNTFKRCFFTCLVLVTCLVTDLSGRHASLKVLSPRLLSGSLCSGLFSASALGVSCSAPNLQDYVRSHNHLRKPPLSPGSLPCKIGFEGCSMVPSIYPLETLHNSLSLRQVEEFLSRVCESSSEAHVKTMKVLCVFSTDGSVPSSTVSSAGPSSPPSPNTETSGQNFGVSG
The following text describes a protein:
Function:
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MKTLFKSLKITLVFCVFFSVFYILILWLFAQVAGPNKGNAEVATLDGKVVGAANVGQMFTKDIYFWGRPSCAGDGYDASSSSGSNKGPTNPEYLAEVEARIDTFLVHHPYLSRKDVPAEMVTASASGLDPNITPQCAYVQVKRVAQARGLTENQVKEIVDQSVEKPLLGIFGTEKINVLKLNIALEENK
The following text describes a protein:
Function:
[Capsid scaffolding protein]: Acts as a scaffold protein by binding major capsid protein in the cytoplasm, inducing the nuclear localization of both proteins. Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid. Autocatalytic cleavage releases the assembly protein, and subsequently abolishes interaction with major capsid protein. Cleavages products are evicted from the capsid before or during DNA packaging; [Assemblin]: Protease that plays an essential role in virion assembly within the nucleus. Catalyzes the cleavage of the assembly protein after formation of the spherical procapsid. By that cleavage, the capsid matures and gains its icosahedral shape. The cleavage sites seem to include -Ala-Ser-, -Ala-Ala-, as well as Ala-Thr bonds. Assemblin and cleavages products are evicted from the capsid before or during DNA packaging; [Assembly protein]: Plays a major role in capsid assembly. Acts as a scaffold protein by binding major capsid protein. Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid. Cleaved by assemblin after capsid completion. The cleavages products are evicted from the capsid before or during DNA packaging.
Subcellular Localization:
[Capsid scaffolding protein]: Host cytoplasm; [Assemblin]: Host nucleus; [Assembly protein]: Host nucleus.
Domain:
Region of interaction between pPR and pAP is called Amino conserved domain (ACD). The region of interaction with major capsid protein is called carboxyl conserved domain (CCD).
Sequence:
MSKVWVGGFLCVYGEEPSEECLALPRDTVQKELGSGNIPLPLNINHNEKATIGMVRGLFDLEHGLFCVAQIQSQTFMDIIRNIAGKSKLITAGSVIEPLPPDPEIECLSSSFPGLSLSSKVLQDENLDGKPFFHHVSVCGVGRRPGTIAIFGREISWILDRFSCISESEKRQVLEGVNVYSQGFDENLFSADLYDLLADSLDTSYIRKRFPKLQLDKQLCGLSKCTYIKASEPPVEIIVAATKVAGDQVQLTTEPGSELAVETCDVPVVHGNYDAVESATATTAMSNQNLPNTTPLLSSPPFSDCVFLPKDAFFSLLNVTTGQQPKIVPPVSVHPPVTEQYQMLPYSESAAKIAEHESNRYHSPCQAMYPYWQYSPVPQYPAALHGYRQSKTLKKRHFQSDSEDELSFPGDPEYTKKRRRHRVDNDDDKEMAREKNDLRELVDMIGMLRQEISALKHVRAQSPQRHIVPMETLPTIEEKGAASPKPSILNASLAPETVNRSLAGQNESTDLLKLNKKLFVDALNKMDS