lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Alpha-PS2/beta-PS is a receptor for Tig, wb and Ten-m. Involved in the function and/or development of the olfactory system.
Subcellular Localization:
Apical cell membrane; Single-pass type I membrane protein. Lateral cell membrane; Single-pass type I membrane protein. Basal cell membrane; Single-pass type I membrane protein. Note=During mid-oogenesis, localizes to the apical, to the lateral and to the basal membranes of follicle cells. Apical membrane localization peaks at oogenesis stages 9 and 10A in columnar follicle cells overlying the oocyte while decreases in the most posterior follicle cells. During embryogenesis, at the end of germband extension concentrates at the basal membrane of mesodermal cells, where they adhere to the ectoderm. Then, in visceral mesoderm localizes basally, whereas in somatic mesoderm is homogenously distributed.
Sequence:
MSGDSIHRRRMALHCPITSLILLLIAMSAHGYNIDLPSYVRFRQSSNSMFGFSIAMHKGRSGFYGNQNNVSLIVGAPKFDTSRYQQGVTEAGGVFKCSLNDDDCKLVPFDSKGNNRNVDKEVVDRKSYQWLGATVATGRDSDLVVACAPRYVFHTMTPSRAFRIDPVGTCFTSHNFEEFYEVSPCRTNNWGYHRQGSCQAGFSAAINGNGSRLFIGAPGSWYWQGQTYSIPPDAKFPFKPPLYQPFGTGGMASSHDVTRPENQVFSTSESASVNDDSYLGYSMVTGDFDGDRSEDVAIGMPRGGNLVGRIVVNRWNMANIFNITGRQIGEYFGYSLATSDVDGDGLDDLLIGAPMYTDPDNVEGKYDVGRVYILLQGGPTEEKRWTTEHIRDGYHSKGRFGLALTTLGDVNGDGYGDFAVGAPYDGPEGRGVVYIFHGSPMGPLAKPSQIIKSEQLVEGAPYPRTFGFALSGGLDMDGNTYPDLAVGAYSSDQVFIFKSRPVAAVNAETSFASNSKLISLDDRSCQLVRDHKKVPCMLLTTCWSYTGRYLPEQLDFDVSWLLDAKKLLNPRMFFLRDEGKNIRNQTIRLNYGQKYCLNETVYLLDKVQDKLTPLEVEARYNLRSSRPLDPMVRHRRSILEPVIDQNREIVLRDAINIQKNCGPDNICEPDLKLKVSTVDKYLFGSPEPLVIEVFISNTNEDAFEAAFYMVTPPDLQFRKLQQLGEKKDTPITCSPPTPENNHTLKCDIGNPLESGKIAHFKISLVPEEKYGSSSSYDFYWEANSTNLEKPGSEYDNKIRQSVGIWVDTDLDIKGTSLPDYQLYKADDYKELENATKEDDIGPQVVHIYEIRNNRPSIIEEAEVFIHLPYETIVGDPLMYLLNQPETGGKIQCDDVAFNEYNLLLDEKLVKKSYLQAQGAIWNSAQVSGQSSSSSSSGGASVHIEKARGEGFVRGVLVSNSTDAGDKLSPKQVEQRRQEDTLEALGDASFVHRDRASQAVQEPQVNQTSFTTYSTSSSSSGSGAPSAQLRGHSTQGHIQMAGPVQHTSSSSSSNYRSWPAQQQQQHQQLLLAGSGGSGLGSPVTFNDKSQFGGRNNNFHTGTLDLGTLNRGNVDNELYRSQGQYQNPSQSLGQSQGQFQANANQGHYQGQNQAQFQARNPGFQGQTSYQGQTQYSGQPGGYQTHHVTYSSGSKPYYGRENEDFYDEDNLQQATPGHWSSSSSSSSSSGTRRLRRSNDKDGATEKPLQIDLNSPCQSARCKSIRCVVTNLGTEDGDAAFVAIRARMVAKTMEKLASNVPLNVSTLAVANVTLLPFIGAPKDAIVKTHEIFYKAEPEPLQVPDVVPLWVVVLAACAGALIFLLLVWLLYKCGFFNRNRPTDHSQERQPLRNGYHGDEHL
The following text describes a protein:
Function:
Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity.
Subcellular Localization:
Nucleus.
Sequence:
MSISQNNFLTMFPVTYTFENGVYSTIINQNTIQTPIPNPIQHHIQNHIQTSIPNTNLLLENVQTDVQKLMVPLIDQQFHIPTSTPLQLAPIPTQIQSQLQPQISQIPIHNQPQIQIQSQVQPQLPTQSQPKPSSKASLDTSSNAFKKYVNPFAPEATVPLPVELEDQYGPYSSSVWKRNERERCRVRNVNDGYERLRKHLPVHFDEKRISKVDTLRLAIRYIKHLDNLLRSELHQYNCKCFNGFQEESEGNILIDISTFNFNSSNNAM
The following text describes a protein:
Function:
Cilium-specific protein required for cilia structures.
Subcellular Localization:
Cell projection, cilium.
Sequence:
MVRECVEESFGPKKMTKKSIVDSCKKNKLYITPHLNDILYLNYSGYNAIESLEEYVGLKCLWLECNAISEIKGLEYQTELKCLYLQNNLITKIENLDSCKQLDTLNLSHNHITRIENCGHDILPVLNTLNLSHNYLKTADNLDHLRHCNFVSVLDLSHNRIEDIAIVKILGGMKELRVLTMTGNPVVNEIPSYRKTLILECKNLTYLDTRPVFDRDRACAEAWKRGGYEEERKELLRWKKEEQRKIRRSINATLRMRHRGDGEPELLKTSSDEEDEDKASKCGKDMSSMLEINQKTNEQAWAEVEKMFCTTPSATGSSGIFQRFATNRGGGADGDGEVIETSEEDIEATIEDIKAVSPKKLIEEISSDSDGAKENYDCKPDEVIAKPCSEKLIEEIVIETAECDSGPSSPEYHEALDKPIENIVNLTNESPLTSPSFDTEPRTLIEEIEPTDVEEEQQIEEQPAPKPLSKNMEKVMSTEKEDDTLNVLIENNEEISITMESKDGELISKVESRPPSTECKKYKIVSTNDVDNSESEPTDITNEDQEYRSSSVSVTSSTDSSDSEDLFDKIVPNKHPKLATNYRQDSTTSTDSENEVSPSKPPIKLEKEKSIAECIDEYKKFFKAAKILESDPEDESSTKMARPHTAKAKRTEPIIYEGVLRNMERNSNESKIAEARTEAKESKEKVIDRLIEQQNLVDMNLEEQNISIGGQEHDFNEYRLEAFRKDQEKLQCLIDRVTAQKDLYNAHIDQIHNQLANIMEDYDQIGLKLKKVDDFLENIKEEPKAPETPSIESEEEIPEELEVHSSEHEQEIVENDNLAQQIIEKIISQSVKTSSEDLKSNFDDSSESSDSAEEDFMDSIRPDHNLLEILTSPKPIPILDPELIPNVDNEFQRDPVYRKFIEIQEEIDKLTEDELYDIVTEATGEFSEEAHVEHCLNTQVDQYWKQYDDIEEFRKNINLDSHPIIQKFRQFIRCHCENKYPGEVDSTIDNLDKACRKLERRLSNQLFDEYLELSRKMSVATIGGESSANEIELIEVDEEENDVEDVVKKITAWVEEQVQNEIAELNEERAAHAGEVMQDTEDVESKPVEIDGTKEETVDSELADNCD
The following text describes a protein:
Function:
Regulates gene expression patterns in meristems and thus modulates organ development. Required for correct embryo patterning and cotyledon organogenesis. Modulates auxin signaling pathway in early embryos. Involved in the cytokinin signaling pathway that promotes shoot regeneration. Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Miscellaneous:
MISCELLANEOUS: 'Dornroeschen' means 'Sleeping beauty' in German.
Subcellular Localization:
Nucleus.
Sequence:
MEKALRNFTESTHSPDPNPLTKFFTEPTASPVSRNRKLSSKDTTVTIAGAGSSTTRYRGVRRRPWGRYAAEIRDPMSKERRWLGTFDTAEQAACAYDSAARAFRGAKARTNFTYPTAVIMPEPRFSFSNKKSSPSARCPLPSLPLDSSTQNFYGAPAAQRIYNTQSIFLRDASCSSRKTTPYNNSFNGSSSSYSASKTACVSYSENENNESFFPEESSDTGLLQEVVQEFLKKNRGVPPSPPTPPPVTSHHDNSGYFSNLTIYSENMVQETKETLSSKLDRYGNFQANDDGVRAVADGGLSLGSNEWGYQEMLMYGTQLGCTCRRSWG
The following text describes a protein:
Function:
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
Sequence:
MAKTKFNIITSTCVPLPLENVDTDQIIPARFLKATTREEKFFGDNLFRDWRYNADGSLNKDFVLNDPTYSGQILVAGKNFGSGSSREHAAWAIAGYGFRVVVSSFFADIHKNNELNNFVLPVVVTEGFLQELFDSIFADPKMEVEVNLPEQTITNKATGKSEHFEINAYKKLCLMNGLDDIDFLLSNKNKIEEWENKASK
The following text describes a protein:
Function:
Together with methyltransferase trm7, methylates the 2'-O-ribose of nucleotides at position 34 of the tRNA anticodon loop of substrate tRNAs. Required for the correct positioning of the substrate tRNA for methylation (By similarity). Also plays a role in the regulation of the retromer complex and is required for the recycling of plasma membrane proteins from endosomes (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MLVEGDKGVLEPVNFVGPVTSLALIHNDKFLCCAQGPCLRIYDVSESRHESDLIKSILLPFHNRIHGMLPCKQGLFVWGGTYFAVVDVETSQVYYDRISDWIFNAAELGEENKFCVVTSKNQVHLLSLSKGSWEVTNTISCEKTPLLFCATVQISGNEIYIASASAFQQIYVWKFNYNNPPSCVSIDTYLVGHEGACFDLKFSSDGRYLCSVSEDRTLRLWSIESSPFLIATGFGHSARVWRCVFLPNKEIATVSEDLTLRLWTWNDKTLTNTYTYTGHRGKHIWSLVVSSANPIIYTGGNDGSVRSWDYKTRIQESCISVSSLFTSKTLLASFCFVKCQKLLCLAKNGEMSIIDNKGKKAIPALTTTSDMSIIRSWKNSFFVAAASNKGTIYVFSYQNTNLLKAIDLHRGKIQQLLTYQVKERYFLLSKSFVGKNQFRVYLQEFDFEADKVNLISTIELELPATFDPTSLTVDEEYSNFLIGSRTGSLALYNIGESNYLSVWRRIHEFDAISSIHIKSSKRDYLLIQTVGRDGYVNLFSIPRVEKSAVPQELCSKKCCDGILSGGLCKKLKNGKENQWVWGFHASNFFLRDETNETNVFFIDCGGSHRPWAFSMEMDIQSFASYRANQLYIYSTALNLLQRNSVLQNGLHGREIRAMDFNPSGDLLLSGSEDTKVTLLEFQSNGNIIPLNSVKFHNSGIQSLTWFSDDILFSTGGLEELNVYRLIQKPEAYLKRIVHEKLCKPNKSNKTYDGDLRITDISVVKATHLGERVLWINTVQSDSTIKAFTYNVDTKQLNCIKSWKYKTVCLVFAEAVIFGSHLLLVVASTDGNVAIWNTFWRDPQIEPLIIWIKTVHQFCVKSLNISRDQDVLTISTGGDDGAISRSILLLEQISENSVVVNSLHNYFFAEAHASSVTGVLSITKELLLSVSIDQRILLWKVEGDSLKPILERYTHVADVGGMIRNNDFLIIYGIGCEVFRLGSLR
The following text describes a protein:
Function:
Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKLRFIINCNIVLFLLWRVMAGKHRPVSEGTMASVSAASVGAGFTPEQEKILSKLLWRIVPFLLLCYIVAYLDRVNVGIASLTMNRDLGISPYEFGWSAGLFFFGYFLAEVPSNLALQAIGARKWIARILITWGLISAATAFVVGPVSFGVMRFLLGLGEAGFTPGVFLYFTYWFPARVRGTATAAFLLGIPIANIVGAPISSSLLTLDGLAGLHGWQWLLILEGLPATLLGFVCFFTLTDKPEQAKWLSPEERSWLAEVLAAERQAIAAKHSSRLKDAFVNWRVLVCAAVNFCAIIGSVGLGLWMPQIIKGLGFSVVAVGFIAAIPYICGAVTMMLWARLSDRGGERSWFVASALLVGAASLIVCGYATSSALISIVALCGAVIGIMCYQSTFWPIPSSFLTGSAAAGGLAMIVSIGNLGGFVGPYLIGMIRQSTDSFSWALISVAAFLTLAAILIRVVGASLQRPGGATDRHTSPIASLSKGI
The following text describes a protein:
Function:
Constitutes the active part of the CARD8 inflammasome. In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of CARD8 (Caspase recruitment domain-containing protein 8, N-terminus), preventing activation of the CARD8 inflammasome. In response to pathogen-associated signals, the N-terminal part of CARD8 is degraded by the proteasome, releasing this form, which polymerizes to form the CARD8 inflammasome complex: the CARD8 inflammasome complex then directly recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, leading to gasdermin-D (GSDMD) cleavage and subsequent pyroptosis; Constitutes the precursor of the CARD8 inflammasome, which mediates autoproteolytic processing within the FIIND domain to generate the N-terminal and C-terminal parts, which are associated non-covalently in absence of pathogens and other damage-associated signals; Regulatory part that prevents formation of the CARD8 inflammasome: in absence of pathogens and other damage-associated signals, interacts with the C-terminal part of CARD8 (Caspase recruitment domain-containing protein 8, C-terminus), preventing activation of the CARD8 inflammasome. In response to pathogen-associated signals, this part is ubiquitinated by the N-end rule pathway and degraded by the proteasome, releasing the cleaved C-terminal part of the protein, which polymerizes and forms the CARD8 inflammasome.
Subcellular Localization:
Inflammasome. Nucleus.
Sequence:
MEKKEFPEKSSSSEEELPRPHSGSSRNTDASKLIRLQGPRKLLVDNSIRELQYTKTGIFLQAEACVTNDTVYRELPRVSEIRCDISHFFQDDDETEAEPLLFRAVPECQLSGGDIPSVSEEQESSEGQDSGDICSEENQIVSSYASKVCFEIEQDYKNHQFLGPEGNVDVELIDKSTNTYSVWFPTAGWYLWSATGLGFLVRDAVTVTIAFGSWNQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQAGEVDVSWFLVAHFKDEGMVLEYPARVEPFYAVLEKPSFSLMGILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLVPSDALLTKMIDDEEDRFCGVRLQTSPPVEPLNFGARYIVSNSAHLEIIPTELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHETLVWKTVVKPVDIQLGAASAPPAFSGAAFVKENHRQLQARLGDLKGVLDDLQDNEVLTENEKELVEQAKTRQSKNDILLTMVEKKGDRALELLFRSISERDPYLVSYLRQQNL
The following text describes a protein:
Function:
Transfers N-acetylgalactosamine onto mannose groups of carbohydrate substrates. Required for susceptibility to pore-forming crystal toxins in conjunction with bre-1, bre-2, bre-3, and bre-4. Involved in resistance to the nematotoxic C.cinerea galectin Cgl2.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MFLCVRILKRKYHELSSFQKLLIFTITIFLLWVLGVVDKFRETSFGDFSWPLETRNLQLRSKFTKYPQCKFSGNGQKIIIIIIKSSAKNGPMRESVRKTWGVFRMIDGVEVMPIFIVGRVENMEIMRRIDVESEKYKDILAISDIDSYRNNTLKLFGAIDYAANPNQCSSPDFTFLVDDDYLVHIPNLVKFAKTKQKEELVYEGFVFDTSPFRLKIHKHSISLNEYPFSRYPPYVSAGAVFLTSETIARFRNSIRKLKMFPFDDVFTGILAKTVNVAATHNENFIFWCRRVSQKEWDDGVIAVHGYARKDLEYEYSQLNGFE
The following text describes a protein:
Function:
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Sequence:
MATEAQSEGEVPARECSRSDAICNFVICNDSSLRSQPVIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKEVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFHVHLKIADLMQFDDKGNKTNVPDKERQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNNGMAFMIKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLTASCHTRSFQLARSQKRNRVDSCSQQEETQQRTEEALRELFQHVHNMPESAKKKQLIKQFNKHSGTQTPGREPATPRVQKRVRSRSFSGLIKRKVLGNQMMSEKKNECPTPESVAFGELKRASKENMNLLFSGSPAVMVTPTRLKLPEGKKEGKKGWAV
The following text describes a protein:
Function:
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSEEMLYFSGLSDVLRMTFVQIMIFSTIAIVIFLYGLISNFQKWGTGVTGYALEPQEGKKGSAITFLKTWWSQVTAESHHRGESILEILILDILFQRRILKRSPFRWVMHLFIFGGWMTLFALSGMMFAVEMTEKIGIALPFTPAEFRDFLSIPNYIFGYILLIGVLVALVRRLFVSEVREASIMYDWVLIGIVFLVTISGFIADGIRTGFIWSFGLDPSVAPPAALFHSIFSLLFCIAFIPYSKYIHIIAIPLALLANKGGE
The following text describes a protein:
Function:
Catalyzes the stereoinversion of LL-2,6-diaminopimelate (L,L-DAP) to meso-diaminopimelate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
Subcellular Localization:
Cytoplasm.
Sequence:
MLLRFTKMHGLGNDFMVLDLVSQHAHVQPKHVKLWGDRNTGIGFDQLLIVEAPSSPDVDFRYRIFNADGSEVEQCGNGARCFARFVQDKRLTVKKSIRVETKGGIIELNIRPDGQVTVDMGPPRLAPAEIPFQAEREALSYEIEVNGQRVELAAVSMGNPHGVLRVENVDSAPVHSLGPQLEVHPRFPKKANIGFLQVLDPHHARLRVWERGVGETQACGTGACAAAVAGIRQGWLQSPVQIDLPGGRLHIEWAGPGQPVMMTGPAVRVYEGQVRL
The following text describes a protein:
Function:
SNARE promoting movement of transport vesicles to target membranes (By similarity). Potentially functions in retrograde trafficking and in the endocytic recycling pathway (By similarity).
Subcellular Localization:
Membrane; Single-pass type IV membrane protein.
Sequence:
MSNYRYSKLNEEEISLEDMPSSANQILTRQEQIIQEQDDELELVGNSVRTLRGMSSMIGDELDQQSTMLDDLGQEMEYSETRLDTAMKKMAKLTHLEDESSQCKMIMVLSALLFFLVFVLLV
The following text describes a protein:
Function:
Catalytic component of the inositol phosphorylceramide synthase which catalyzes the addition of a phosphorylinositol group onto ceramide to form inositol phosphorylceramide, an essential step in sphingolipid biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein.
Sequence:
MSALSTLKKRLAACNRASQYKLETSLNPMPTFRLLRNTKWSWTHLQYVFLAGNLIFACIVIESPGFWGKFGIACLLAIALTVPLTRQIFFPAIVIITWAILFYSCRFIPERWRPPIWVRVLPTLENILYGSNLSSLLSKTTHSILDILAWVPYGVMHYSAPFIISFILFIFAPPGTLPVWARTFGYMNLFGVLIQMAFPCSPPWYENMYGLEPATYAVRGSPGGLARIDALFGTSIYTDGFSNSPVVFGAFPSLHAGWAMLEALFLSHVFPRYRFCFYGYVLWLCWCTMYLTHHYFVDLVGGMCLAIICFVFAQKLRLPQLQTGKILRWEYEFVIHGHGLSEKTSNSLARTGSPYLLGRDSFTQNPNAVAFMSGLNNMELANTDHEWSVGSSSPEPLPSPAADLIDRPASTTSSIFDASHLP
The following text describes a protein:
Function:
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Sequence:
MTQEFINAVVQYTTGSLQNRQEAESYLVQLETQPQAFNIGMSIIQGNYSHPNQPQITQTILYFALKLIESSTKNVQNFNGITRKQLSISLLDWCLTQPAGMAMKKAIHTSISLMISNNQFLPSEWPITIINLKNKVTTELQSLVIILTLKEINDELIEKSKAFSQLTDLSNKVKDAFRENGVKEIVDFLYRCMTNEHLVKDSLELFGTLVSWIDISFSTNSEFVQRLYSYLNSPALFNPTIFIFSEIISKGMDPMVKLSLIHSLQLIKFIPIPNNSNEDSFTSVCKLSGVIINEILAATERKFPVKALVTGRVQIQPEVFNTIQEMLSSNFIFFVNLFQRSSLDMAKEFSSGITKAINDFFAPLLNKFIIPNSLVEVESILLQALYSKYQMFIKNEFDDDGNNGSDLLNCLKTIYRASSDLDQSCLVLQQFLQQLMTFNLKNPSVESVSCHAYFILHFPDKLMARPETVQFMTQHVTTFSQQFIRFVDIAVEHSPIYPAISRFLKYISGDCLYGIIEYSIGVVEKGKCFSEIKDLVREARSNGMNPRQEWSLKVGQIVKNVAETIWIKRNVIETVDLYSILSDLTDSGLSVVIKEVFGPEIEHCNSLGNNGDIQFTTQYIGSRLKNVSAFLKKNGFTSRRESFTLYNEYCPIVERIIRGEIQCDKMNIKKYVVDFVQMWIEAINPEFHVIPSIQAMSNYLNESVNDILLLGTLMTHLLSKQNKLNVVILGNEFKFVLQGFLNSLDGTDQLNETSELFREKMDIAKVIFSLMTFPPQMYHVFNEFDYTIFIKNIMFIIEKLRSDELAKMIEKYCMKSIEIYLMTNGEIGKSIGINIWLQLFTQIINRVKLTKNYGMSFCIVEGFKSLVGLIQKYPVLIEMIKSFISTLPSDKQQWVSIFYSTLIQCQNVTVPQVMNLLKGFI
The following text describes a protein:
Function:
An odorant receptor which affects chemotaxis to the volatile odorant diacetyl. Specifies AWA neuronal cell fate via the odr-7 pathway.
Subcellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein.
Sequence:
MSGQLWLALVDAADMVGFTLTISINIILLGLIRTRGKTLGTYKYLMSFFSFFSIFYAIVESILRPIMHIENTTFFLISRKRFDYSTRLGKINSAFYCACFATSFVLSAVHFVYRYFAACKPNLLRLFNLPHLLLWPLMCSIPVTAWASVSYFLYPDTEYTEAAVTYVLKTHYEVIKKENVSYIAYVYYQYENGERHIYIKNLLGCFVHYFVMSMTFVVVFYCGFSTWWTIREHRGASDRTRHLHRQLFKALVFQTLVPSIFMYIPTGVMFIAPFFDINLNANANFIVFCSFLYPGLDPLILIFIIREFRVTILNIIRGNERGNAVGEAYSTSRIKSSQPAAVNLSG
The following text describes a protein:
Function:
May play a role in anteroposterior axis elongation.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MPAASRCMALLRALLGALLLPMPGVWCFSELFFVREPQDVTASRKDAVVLDCQARGEAPITVTWLKNGGKVSENERIYTLSNGSLYISEVEGRKGEQSDEGFYQCLALNKYGAILSQKSHLTLATISAFEVQPLSTEVQEGGVARFTCKIAANPPAVVTWEVNRTTLPLSMDRITALPTGVLQIYGVEQKDAGNYRCVATTITSRRKSAEATLNVIPASDLKPFHKPAIIAGPQNVTASLHQTVILECVATGNPKPIISWSRLDHKSIDVFNTRVLGNGNLMISDVKVQHAGVYVCRATIPGTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGTARFACQAEGIPAPKISWLKNGRRIHSNGRIKMYNSKLVINQIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAPYNVHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVAYMPLGASQMSDHVTQHTLEDVPLRAPEISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTDSKIQVLELPGTSDEYLLEGLRPDSVYLVRITAATRIGWGEASLWTSHRTPKATSVKAPKSPELRLEPINCTTITVQWQQDSDDTAAIQGYKLYYKEEGQQENGPILLDASDLEYTVSGLDPRRKYHVRLLAYNNMEEGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIYLHWGKPAFTSAQVINYTIRCNPVGLQNASLVLYLQTSETHMLVQGLEPKTMYEFAVRLHVDQLSSPWSPVVYHTTLPEAPSGPPVGVKVTLIEDDTALVSWKPPDGPETVVTRYTILYASRKSWIAGEWQVLHREGAMTMALLENLVAGNVYLVKIAASNEVGEGPFSNVVELAVLPKETSESNQRPKRLDSGDSTAYSDYYHLDQKSMTGIVVGVCIALTCILICILILIYRSKARKTSAPKPVQQSTDQLSHTNISLASANEVEKSIDGIAENAESLLPMIVGNSFIDAKGGSDLIINSYGPVTKANCKKRWLFFQDTKKMKTEEPQRRFVQAVCLYQPGTTVLISEDDSPSSPGQQSNFQVPFSIAADTEHSANSEGSHETGDSGRFSHESNDELHLSSVTSATPCATSHFVSSDLGKNVMNSTISDSKESPLLFATDQPATSPLQIHSAVQN
The following text describes a protein:
Function:
Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface (By similarity). Negatively regulates Wnt signaling, possibly by antagonizing the recruitment of AXIN1 to LRP6 (By similarity).
Subcellular Localization:
Cytoplasm, cytosol. Cell membrane.
Sequence:
MEGAEGNAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLSSISAHELHRAVREVLQLPDMALEAFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTDASDDDIAMDEPSLQFRRNVFFPKRRELQVHDEEVLRLLYEEAKGNVLTARYPCDLEDCEVLGGLVCRVQLGPYQPGQPAACTVREKLDSFLPAHLCKRGHGLFAAFRGRGAKTGPCEQGLLNAYRQVKEMAGGDSERETTLGSHYRAYLLKCHELPFYGCAFFHGEVDKPTQGFLHRGGRKPVTVAISLEGVHVIDNREKHVLLGLRFQELSWDHTSPEEEEPVLWLEFDGDSEGTPVNKLLRIYSKQAELMSVLIEYCIELSQAAEPALPQESASGPQEAPSPSSAPTQRPKLRRQGSVVCSRIQHLSTIDYVEDGSGIKRVKPKRTTSFFSRQLSSSHGSYTVVQPNDNSPEQG
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKRSHFNKPLEFVILVAKILGIVPLSSGPQRKRVRVLLILKQVLGFCGIVFICWLHFFHYSCTKIKFSYLSSTISSILNVGYNVLMCIGTYLISILYEKKYRSVSVVISSFDQSMESRVKSRKKISTVETIVFGLSVTFVLVILCVQFGHYFRNYRRNNFCILFTVLSLVITTVVFLLNFVLLIGVSKRFKLLNKYFKSIIFLAVDYENSNVSLVRETEECSKLCHMLMVTAELVNQIFELFIAIDFMIFFCLLIFLIFYLSADNDTFRDRFPTKIEMYTMFFWTLVAFLKTVLTTYAFKSVATEANHYNRIVHSIRSESVIPKNLVTHYFFLNYPLSKTFKVITISHQLNFYSSQFTVFEMFPLEWSNLFTILVSAMMYSIFFLQLNGGKNYILFLS
The following text describes a protein:
Function:
Component of the endomembrane trafficking machinery that is involved in protein recycling to the plasma membrane. Forms a complex with BIG5/MIN7/BEN1 and actin to modulate the function of the trans-Golgi network /early endosome at the intersection of the exocytic and endocytic pathways. May be linking post-Golgi traffic with the actin cytoskeleton.
Subcellular Localization:
Cytoplasm. Endomembrane system. Golgi apparatus, trans-Golgi network. Early endosome.
Domain:
The C-terminal domain (496-565) is responsible for the localization to the trans-Golgi network/early endosome.
Sequence:
MADTVEEPQLQNGAAPAESETEQNPIPEPQLQTEPKLTGEIPEIEADLTPEEVQSEVTDAKPEEVQSEVKPEEVKTVVTDAKPEEAQSEVKPEEVQSVVTDTKPDLTDVDLSPGGSEEIPIRSTEVEQESTTSVLKKDDDGNKTFTMRELLSELKSEEGDGTPHSSASPFSRESASQPAENNPAMDLINRIQVNDEEGRSRQRVLAFAARKYASAIERNPDDHDALYNWALILQESADNVSPDSVSPSKDDLLEEACKKYDEATRLCPTLYDAYYNWAIAISDRAKIRGRTKEAEELWEQAADNYEKAVQLNWNSSQALNNWGLVLQELSQIVPAREKEKVVRTAISKFRAAIRLQFDFHRAIYNLGTVLYGLAEDTLRTGGSGNGKDMPPGELYSQSAIYIAAAHSLKPSYSVYSSALRLVRSMLPLPHLKVGYLTAPPVGNSLAPHSDWKRTEFELNHERLLQVLKPEPREMGRNLSGKAETMSTNVERKTVKVNITEIVSVTPCADLTLPPGAGLCIDTIHGPVFLVADSWESLDGWLDAIRLVYTIYARGKSDVLAGIITG
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPTVRYQIRNEYGLADPELHRTADKDDPEAILEGVAMAGLVGVLRQLGDLAEFAAEIFRDLHEEVMGTAARGHGLMLRVQQLEAELPSVEKAIFSQSSHSNFAYNDGIDWHSSIQMDQNLITQGDMPRFILDSYEECRGPPRLFTLDKFDTAGAGACLKRYSDPSFFKMELVSSGLVETEIPREKKSRKMRKKGSNWKKGQTLESLLSPLADSTSQTTVSDQVSSKSATRLVRLRYRNSNNTNGSKGCNLRKCLLALHSDEQKVVLDNSRRHSSLNVNLVDSGELTSVMHDTVMDVSANYPLVRDVSATETPTKEVVKLTYKFDHWKTGTEEFSEALHGPLGDMQNPQRNFNFVENKEKFADAENKSESSNCDGELSDTEKTTSVQVADHKLGDIEHILEDSNNGYKTEDGGSEQENFMDALNSMEPEVETDSENKDRPDLGVTQKEAYDMNFYTSETLDELLTQFSKQDMAAVSIVSIGLNHNLKSGISSNLCNLSETPATQEKEITSNSSANSEYLLGETNDESCEECLPHDEVANSFDMISDGASDIKSFDNPILRSEIGEEPCNSCDINSTSNLISTGPQQGFETLQFVKAYHVGTSADHEAQLGRDETIKCSDGSPHSNRSDPEIHQPPELVEELVLEGITEMLDMPNRLSSSPARTLPMEDHGNEGSPFITAPTEKETQDSMDQGTKSFAFKNDTTASLGGRSIITTAPHFDPDISIIQHDVALDINICQYPEESTIETSSDYLKGTDGVEYPEESTVEISSEYVKGTDDVVQTMNGPSIGSKDDIISENPYPPCNPVELILEEMESGSGMSDYLSESKYESSLTEVFEGHIEVVSHPSNASIEKSPQLTDQDAEVCSTESTPILISAIVPITDKDCTEKLENIDVENLEVGCEDTDDMTKQNLAMPEIPQPQLEHFSGTEETLQSPKVKLAEPQESHKTNSTEQVPLCFESETFFDRVINYPVLVGDGLKLANEYIQENLQSDVQGFEQITDVKDMSAENFASEDETNSYDSSPVYTKESSGLPLQLVEDSIDSAVSYQHQMKTRETFNPKMAKSLDSQSTPDMAVFSGVEQSAQDPVASHGLPVEDSSDANDDGLHGDICDMMPNVHVHGNLHPFVNDTCLEYPVESKQDFGPKYSAQGHHESAKQEMSLSANLLLDHASASLPEEAFTLQASNEVEIESSHQKGEYFELDIPINSVDVDEEPSEGPEQNHHAFMSNVKYDELDITPSSTTMTEKLGSALVSSECCSEISACQIASNVSDMTFSLSPSSVVFVTESTSRLSSEPQSDESTSCFPSQNSEEPPPLPPLPPLQWRTQKLQVSSLLPNANSSASLAVTNPFVTPSDIKPANKFITSPSGLSELPPIVVDQSHQSDAQCLEGNLVHSSNSLSLISSSLVYEKNMHAPDAQEVLRLPLADSFISQLWPGSDLEKFHYSEHNHLKLEKEVIQPQNLFLFESTLEDYNHHHNYGDFGGESAHLLKSSDLSLFSRLEMPQSGYVYSLEGSHSTPFGVVPTREDEWHSIKPHSIRNRPRNPLIEAVAAHDRSTLRKVPEQAKPSNESKADKKDAVLESNILQLRKVSEHMKPSNKPKADERDELLEQIRNKSFSLKPAVLSKTNNKGHSTNIKVAAILEKANALRQAMVGSDEEDGGDGWSDC
The following text describes a protein:
Function:
Lymphoid-specific receptor expressed by all T-cells and in a subset of B-cells known as B1a cells. Plays a role in the regulation of TCR and BCR signaling, thymocyte selection, T-cell effector differentiation and immune tolerance. Acts by interacting with several ligands expressed on B-cells such as CD5L or CD72 and thereby plays an important role in contact-mediated, T-dependent B-cell activation and in the maintenance of regulatory T and B-cell homeostasis. Functions as a negative regulator of TCR signaling during thymocyte development by associating with several signaling proteins including LCK, CD3Z chain, PI3K or CBL (By similarity). Mechanistically, co-engagement of CD3 with CD5 enhances phosphorylated CBL recruitment leading to increased VAV1 phosphorylation and degradation (By similarity). Modulates B-cell biology through ERK1/2 activation in a Ca(2+)-dependent pathway via the non-selective Ca(2+) channel TRPC1, leading to IL-10 production (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MDSHEVLLAATYLLGTLAAFCLGQSGRGFVGAQVMLSGSNSKCQGLVEVQMNGMKTVCSSSWRLSQDLWKNANEASTVCQQLGCGNPLALGHLTLWNRPKNQILCQGPPWSFSNCSTSSLGQCLPLSLVCLEPQKTTPLPTTTLPTTMPEPTAPPRLQLVPGHEGLRCTGVVEFYNGSRGGTILYKAKARPVDLGNLICKSLQCGSFLTHLSRIETAGTPAPAELRDPRPLPIRWEAQNGSCTSLQQCFQKTTVQEGSQALAVVCSDFQPKVQSRLVGGSSVCEGIAEVRQRSQWAALCDSSAARGPGRWEELCQEQQCGNLISFHVMDADRTSPGVLCTQEKLSQCYQLQKKTHCKRVFITCKDPNPVGLAPGTVASIILTLVLLVVLMVMCGPLIYKKLVKKFRQKKQRQWIGPTGVNQSMSFHRSHTATVRSQVENPAASHVDNEYSQPPRNSRLSAYPALEGALHRSSTQPDNSSDSDYDLQVAQRL
The following text describes a protein:
Function:
May be a cell surface adhesion protein.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MEPKTAVLVSALLCLALSRGALSQKARAPIVEAPAPAPAPRYVELAELLSLAGPYGKFLEYLTMTDVIKTFQSQANDTKQGITVFAPQNSAFAALNETVLSNLTTDQLRSLMLHHAMPRYYPLSAFSKLAAASPVSMYAYKVNVTYAAGTIGVVSGWATAKLASSVYSTSPVAVYALNRVLLPKEIFPATPEMAPAPAPGRGGKATADAPGASERAASDNADAKSSSCRVVGAGSLAFGYVVLLVSGLLMA