lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MSEVNIDAGLFYKRLSIFQKQLTANNIPQALIIVGARSDDNTYKKSTVLQNWLLGYEFIHTAIYITDKKCIFITSEGKSKHLKHLTNQKPDLVELWIRTKDVEHNKQLFIKLLETMTKLDSKYGKILKDKYDGKFIDEWNQILNDDNNNNNNNTTNDHALSAVDLAVTVSQALAVKDSEEFNNTKIASNASVVMMDTFVNDMMIIVDDEKKITNSQLTDQIEDKIENNKWYLKTKLGKNLLQSIKDFDPEYLEYCYSPIIQSGGDYDLKPSAVSTDKPLIGEGVILSSIGLRYKSYCSNIARTFLIDPTSEMETNYDFLLQLQKYIVDNLLKDGVPANKVYQDTIDYIKKERPDLVNHFTKNCGWLLGMEFRDSTFILNAKTTDRKLTTGQIISLTIGFNNLSNDKNDKNDKNDNKTNHQKNKQTYALLLTDTIKITDDSSILLTNYSKDRAAISFSFNDDNETQKENNNNNNKRPGLSQTSNTTALKLESTENTAILKSKLRHENTNADDANSEKLRQEIQIKLHEKRLQEGLARFSKADATDADDFKPIFKKYESYVRESQIPNSVNDLKIHIDYKNQTIILPISGRPVPFHINSYKSGSQNEEGDFTYLRLNFNSPGAGGNVTKKQELPYEDSPDNSFLRSITIRSRDRQRMVDVYKAIQDLKKDSVKREQEKKQMADVITQANLIELKGSRVKKLNNVFIRPTPDTKKIGGVLQIHENGLRYQSQPQSQSNFKNDQRVDVLFSNIKHLFFQPCKDELIVLIHCHLKNPIMIGKRKTFDVQFYREASDMAFDETGGRKRKYRYGDEDELQQEQEERRRKALLDKEFKGFAELIADSSHGMVDLDIPFRELGFQGVPFRSSVLCVPTRDCLVQLIDPPYLVVTLEEIEIAHLERVQFGLKNFDLVFVFKDFNKPVVHINTIPVELLEDVKSWLTDVDIPISEGQMNLNWVQIMKTVLADPYQFFIDGGWAFLTGQGESDEEEESDEESDFRVSDEDPQDEDEESDDYASEEESDDYSGSDDDGSGGGGDDDDDDSESGEDWDALERKAAKADRNSGFD
The following text describes a protein:
Function:
Catalyzes the oxidation of hydroxylamine to nitric oxide with cytochrome c acting as an electron acceptor. Does not oxidize hydroxylamine to nitrite. Also able to catalyze the four-electron oxidation of hydrazine to N(2) in vitro with reduced efficiency; however, this reaction is probably not physiological.
Subcellular Localization:
Anammoxosome. Note=Preferentially, localizes in the proximity of the anammoxosome membrane.
Sequence:
MFEIFKKPLSRIVGATFAFAGVTLLACAMENGVAMAEGPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEIHH
The following text describes a protein:
Function:
Probable motor protein.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSRMFLKASFDYSYWSHTSVEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLCEDLFSRVNVNQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRSHDQLTGLDSEKVSKISLVNLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADLQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAVINEDPNARLIRELQEEVARLRELLMAQGLSASALGGLKVEEGSPGGVLPAASSPPAPASPSSPPPHNGELEPSFSPSAEPQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREALLAEMGSPGGWRTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVGQVDVDIKLTGQFIREQHCLFRSIPQPDGEVMVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHPEQARLERERGVPPPPGPPSEPVDWNFAQKDWLEQQGIDIKLEMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGEDSDKRSCEESWRLISSLRDELPPNTVQTIVKRCGLPSSGKRRAPRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMRELCRTYGKPEGPGDAWRAVARDVWDTVGEEEGCGGGGGGGEEGARGAEVEDLRAHIDKLTGILQEVKLQNSSKDRELQALRDRMLRMERVIPLTQDLEDDNEESGLVTWAPPEGSEAVEEAVSNDHSPAVRPSSPPQSSWERVSRLMEEDPAFRRGRLRWLKQEQLRLQGLQGSGGRGGGLRRPPARFVPPHDCKLRFPFKSNPQHRESWPGMGSGEAPGPQPPEEVTAPPPPPNRRPPSPRRPHRPRRNSLDGGSRSRGGGSTQPEPQHLRPQKHNSYPQQPQPYPAQRPGPRYPPYTTPPRMRRQRSAPDLKESGAAV
The following text describes a protein:
Function:
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.
Subcellular Localization:
Secreted.
Sequence:
MAKSFASFAASAALLVAAATAASLPDGTWPASTGTVQYSAAYTVKAGEVFDGKMQTFERSDISCEGQTESGSSTAVFLVEAGGTLKNAIIGKNQMEGVHCDKHDCIIENVWWDDVCEDALSVKGGSASSVTKVIGGGARYADDKVIQHNGYGTVEIDGFYGEDISKLYRSCGTCGDKARKVSVSNVYVVNPGNAVVTVNKNWNDEATLSNIWIKSSKSTVKVCQWSQGNANGEPTILGNGPSAPLCQYSESDVHINEDISNAAQTSPSSTSSSSGVTQTASSSSTDSSVASSASSSQVPTQASSSSTASSLSSSASASASASSQISSNSSSTDDSDAAGPGTVSPVESGSFEQSVVSTDASRTEQQESTEEPTSAPSLSTSSSGSVDPSSEDNSGSDSPTQSSGSDVPTQTATNSSGSVPDGTWPASTGTVLYKKPYTIKAGEVFDGKMQTFERSDITCTGGEGQKDTAVFLVEAGGTLKNAIIGKNQKEGVHCDDHDCTIENVWWDDVCEDALSIKGGSASSVTTVTNCGARYAEDKVVQHNGYGTVKIKGFFAQEFGKLYRSCGTCGNIPRTVTVENVYAIDPLVSVVTVNKNYNDKATLKNIYVKTTDGKDDVKVCQWSQGNKTPSNLGDGPSGSLCKYTESDIHINEE
The following text describes a protein:
Function:
Catalyzes the ferrous insertion into protoporphyrin IX.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MISRKIISTINSKTFYNKSLSYCTVNNNKNTTININNNNEKPKIKTGILMLNLGGPSKLEEVEPFLTRLFTDKEIFKLPFQKYTGTLIAKRRSNAVMKLYEAIGGGSPIRKWTEKQGELLSSMMDKISPETAPHKHYIGFRYSDPLIADTLDQMENDNVERVVAFSQYPQYSCTTTGSSLNNLWKTLEEKQMQSKFKWSVIDRWQDHKGFIDATIHKIKKAYNQFNSKLRELDIDDVDANNNNNNNKPVLVFSAHSLPMSTVEKGDPYPQEVAETVCRVMDGLGIRDEETGKPLEYILAWQSKVGPLPWLSPKTSFVIEQLAKKGRNAIVIPIAFTSDHIETLSEIDIELQHLAKKCGMKLLVRSESLNDDPLIISAMADLVNTHLKSNKTIHSNQYHLKCPGCKDDSTFCRTISNPIQALKL
The following text describes a protein:
Function:
Lacks protease activity in vitro.
Subcellular Localization:
Membrane; Single-pass membrane protein. Cytoplasm.
Sequence:
MAFQGCDCFGLLVWLLLLQTRLGKARMVPGTPSLSPLPSENGLDDSGVNPQERPLTGMPETSLPRKPGDSTRPLDSMAFTPGQSFSTMSLSRQPFPTWVPPTSACGHRTARIVGGRPAPARKWPWQVSLQVHKQHICGGSLISKWWVITAAHCVYGHLDYAVFMGDADLWSKRPVRIPVQDIIVHQDFSMMRTVVHDIALVLLAFPVNYSVNIQPVCIPEKSFLVQPGTLCWVTGWGKVLEQGRSSRILQEIELNIIRHEKCNQILKDIMGNIFTLVQEGGVCGYNEKGGDACQGDSGGPLVCEFNKTWVQVGIVSWGLGCGRIGYPGVYTEVSYYRDWIIKELSRASCWKLSGFLVLSVCLVLHLAIVVAL
The following text describes a protein:
Function:
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MKVLREVVTTNENSLRQLGVLLDSTFVIENEVQIDIDKDFFDSSAGHRKLIDQCIVFLLQKRLLNNVLVAGYKLAKNNTVRSILHCENSNSAVKTLKSSSWELLHTNIGSPKFVNLILNHSIFTFNGEFTQQVAGNSLNKPHLPPSWIIDNDYEQETDINCFSINNRPYLYHNTRGFCIKSIILDRDMLNETLDIQVKYLMREIFENDIKLNKKALRTTVIETVLKQVLENQQRIPIIPILDKICPKTYSNYHLDRATPVKCVNKFIVVILEKLKILQLIGSRKNSFVLFSKISQLLKLPLNGKINVKEFFTKLNVNAVRRYLSIDPIGQQKQSMRLYLTCVVNYLLSKLIPSLLKSFFYCTEVSSYSKILYFRNDEWNSISTPFLKEYLDKYLVQNTHCNSHFSYMESQFNHCNFRLIPKKGNNEFRVIGIPYKGNNAEELLQYKQNHTKVIVPTKLILDYLRKSRQTTQKLLFSAMQISDHICQYKCHLHSKYGYIPKLFYLKFDIHNCYDSIPIAKAKSVLNSLINNCGYEEFYVRSVTILNTKNNEVRYDTIVNGHINIRDFEIMVDNSTTTFLTKEDIMDLIEFEMEMTSIRLFDKCYLRKDGLFQGLSLSATIVDILYDDMLEKNRVFKDILNNDGLVLRHADDFLLISPSKEIISYARLKINEGFTEYNAQVNHRKIVFSESDNIANTAIPFCGVEIIPRTLEVIKRFSAMNETDISDHEGNIYSKCAVLFKMRLNYGTMNANLNSISTMLKQVENATINIVRIILNSNHIATSVSSFSSFVNELYNICLLSSRNLNLLNHRDLQRFLTSIKKTILTVLLKNLKRKYSIYNGISRNMNSKRTSK
The following text describes a protein:
Function:
Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
Subcellular Localization:
Nucleus. Chromosome. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser-377 is restricted to unsynapsed chromosomal regions (By similarity).
Sequence:
MATAQLQRTPMSALVFPNKISTEHQSLVLVKRLLAVSVSCITYLRGIFPECAYGTRYLDDLCVKILREDKNCPGSTQLVKWMLGCYDALQKKYLRMVVLAVYTNPEDPQTISECYQFKFKYTNNGPLMDFISKNQSNESSMLSTDTKKASILLIRKIYILMQNLGPLPNDVCLTMKLFYYDEVTPPDYQPPGFKDGDCEGVIFEGEPMYLNVGEVSTPFHIFKVKVTTERERMENIDSTILSPKQIKTPFQKILRDKDVEDEQEHYTSDDLDIETKMEEQEKNPASSELEEPSLVCEEDEIMRSKESPDLSISHSQVEQLVNKTSELDMSESKTRSGKVFQNKMANGNQPVKSSKENRKRSQHESGRIVLHHFDSSSQESVPKRRKFSEPKEHI
The following text describes a protein:
Function:
May regulate flowering time by modulating the photoperiod pathway.
Sequence:
MEGTDDASALQEPPDPEVLEVDPTFRYIRYKEVIGKGAFKTVYKAFDEVDGIEVAWNQVRIDDVLQSPNCLERLYSEVRLLKSLKHNNIIRFYNSWIDDKNKTVNIITELFTSGSLRHYRKKHRKVNMKAVKNWARQILMGLRYLHGQEPPIIHRDLKCDNIFINGNHGEVKIGDLGLATVMEQANAKSVIGTPEFMAPELYDENYNELADIYSFGMCMLEMVTFDYPYCECKNSAQIYKKVSSGIKPASLSRVKDPEVKQFIEKCLLPASERLSAKELLLDPFLQLNGLTMNNPLPLPDIVMPKEGAFGDRCLMSEGPPTTRPSKTLSIDLDEDSNLPIVTFSDNSGSRCIEVRRAKRGNFFVLKGEENDEQSVSLILRIVDENGRVRNIHFLFYQEGDTASKVSSEMVEQLELTDQNVTFIAELIDILLVNMIPTWKTDVTVDHLIHSQLNQNSRSHHNEAKPQKQEETVFHDTCELVSHSCNSDCPRSDEEDKQCVDATKGEDKSSIQEVEEATEPVSLEEEERLRQELEEIEAKYQEDMKEIATKREEAIMETKKKLSLMKLK
The following text describes a protein:
Function:
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. May be involved in poly(A)-site recognition. May be involved in the association of the CPF, CPFIA and RNA polymerase II complexes.
Miscellaneous:
MISCELLANEOUS: Present with 3060 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MTYKYNCCDDGSGTTVGSVVRFDNVTLLIDPGWNPSKVSYEQCIKYWEKVIPEIDVIILSQPTIECLGAHSLLYYNFTSHFISRIQVYATLPVINLGRVSTIDSYASAGVIGPYDTNKLDLEDIEISFDHIVPLKYSQLVDLRSRYDGLTLLAYNAGVCPGGSIWCISTYSEKLVYAKRWNHTRDNILNAASILDATGKPLSTLMRPSAIITTLDRFGSSQPFKKRSKIFKDTLKKGLSSDGSVIIPVDMSGKFLDLFTQVHELLFESTKINAHTQVPVLILSYARGRTLTYAKSMLEWLSPSLLKTWENRNNTSPFEIGSRIKIIAPNELSKYPGSKICFVSEVGALINEVIIKVGNSEKTTLILTKPSFECASSLDKILEIVEQDERNWKTFPEDGKSFLCDNYISIDTIKEEPLSKEETEAFKVQLKEKKRDRNKKILLVKRESKKLANGNAIIDDTNGERAMRNQDILVENVNGVPPIDHIMGGDEDDDEEEENDNLLNLLKDNSEKSAAKKNTEVPVDIIIQPSAASKHKMFPFNPAKIKKDDYGTVVDFTMFLPDDSDNVNQNSRKRPLKDGAKTTSPVNEEDNKNEEEDGYNMSDPISKRSKHRASRYSGFSGTGEAENFDNLDYLKIDKTLSKRTISTVNVQLKCSVVILNLQSLVDQRSASIIWPSLKSRKIVLSAPKQIQNEEITAKLIKKNIEVVNMPLNKIVEFSTTIKTLDISIDSNLDNLLKWQRISDSYTVATVVGRLVKESLPQVNNHQKTASRSKLVLKPLHGSSRSHKTGALSIGDVRLAQLKKLLTEKNYIAEFKGEGTLVINEKVAVRKINDAETIIDGTPSELFDTVKKLVTDMLAKI
The following text describes a protein:
Function:
Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
Subcellular Localization:
Cytoplasm.
Sequence:
MKFNIRGENIEVTPALKEYVEKKLSKLERYFDTFPEIKVNLKVYSDKQRVEVTIPFTDLLLRAEETNSDMYAAIDLVVDKIERQIRKHKTKVNRKLREKGSIKTNFILPEAVAVLDEVEEDELELVRTKRFDLKPMDVEEAILQMDMLGHNFFVFTNADTNETNVVYGRKDGKYGLIETK
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MLVNKKISSVELNALAALKIIKHCKDGFPATCSGQLLGIDAVGKLQITNAFPFTAEAAVGEDVFDGTDYQTQMLCCLRALNFDANSVGWYQSTYMGTYWNQAIIDAQYNYQKNSPHAVMIIYDPSGTSQGNLSLKALRLSDTFMQVYETRKFSTENILEHKLTPGSVFETIPLKISSSHLLNTALLEVSNQSNLSSTTCSAFSFPSFQFASHLSSDAAPLTPNFDNLELSSETYLEKHLERMVESVEEHGQEQWRWQGWQRSFNKEQIRSQHHISQMNADNAAAIAAGNPPIHHEEDLKVPLSSFAKVASNEPSRLETLIISNQLDTYCKQINQFAGPTLTKMFVAKSFQPQK
The following text describes a protein:
Function:
Part of a potassium transport system.
Sequence:
MRLIIIGASSLGMHLTHTMIRQGNEVVLIEKDEEVARELAEELDCTVINAEGTHPDILEKAGMDCTDAVVACTNHDQDNILIGLIAQEAGVERVIVKTDDTKFMEIAKKLGISSPINPPHISSTIISDALRGIDTIELSNLIRADVRVISFTTGEQHAGKRISEVQFPENTECIGFYRNNDFILARENPKLEEGDELLIITRSGHIDRIYEKLRET
The following text describes a protein:
Function:
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
Sequence:
MASSSTTGEEKMLTLKSGDNEEFHLEESLVLQSDLIKTMVKEERVSTIPLPSIKSKTLVKIIEYLKKHAELTATSNKEDFKNFQKEFVNVVLEELLDITVAVNYLKISGLLEFCCQAVADRIKDKSVEAIQKIFKIESDFTSEEVAEFKRETPWAFEGDLDDTTN
The following text describes a protein:
Function:
Cargo protein of a type 1 encapsulin nanocompartment. May help nucleate Fe atoms in the interior of the encapsulin nanocompartment (Probable). Present in about 47 copies/encapsulin nanocompartment.
Subcellular Localization:
Encapsulin nanocompartment. Note=Probably lies against the interior face of the nanocompartment.
Sequence:
MAKNSNPSAFDRDFGYLMPFLDRVAAAASDLEDASARAELTRLMVEEKARWQRIQELLGGAGGRGAAAPTPAREAPAEAPRLARGSADELHEAAPFATGLTVGSLRGSR
The following text describes a protein:
Function:
Transcription factor. Efficient DNA binding requires dimerization with another bHLH protein, such as cky-1 or ahr-1. Regulates transcription of target genes, probably acting in complex with cky-1. Has a role in cellular differentiation. Required for pharyngeal development. In collaboration with ahr-1 it is involved in RMEL/R and SDQR neuron cell migration. Acts in the cellular response to hypoxia. Involved in aggregation behavior by regulating soluble guanylate cyclase gene expression in the URX neurons.
Subcellular Localization:
Nucleus. Note=Nuclear location dependent on hif-1 expression in intestinal tissue but not in neuronal cells.
Sequence:
MAQDIFMDPWQSATSFAMEDEDMGMPSGKYARMEDEMGENKERFARENHSEIERRRRNKMTHYINELAEMVPQCASLGRKPDKLTILRMAVSHMKGIRGHTAQDETSYKPSFLTDQELKHLILEAANGFLFVVCCQTGKVLYVADSITPVLNLKQEDWLQRNLNELIHPDDQDKIRDQLCGSEVSVNKVLDLKSGSVKREGASTRVHMSCRRGFICRMRVGALEPLHRLRNRRPLFQHAGQNYVVMHCTGYIKNAPPQGINAPASSCLVAIARLQVASMPVCADPTSTNQFSVRVSEDGKMTFIDARVSDLIGLSSDQLIGRYWWNLAHPADEKTLQDSFVALLSDQPMRINIRVRTSTDYIPCTVSAYKFMNPYSEQFEYVVATHQIAPQEDINNWVTAPTVPQPQASEFGELGGAPSAVDYGQSSSGGWRPEAQGAPQAQWQWDPMNGYNQ
The following text describes a protein:
Function:
May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
Sequence:
MKEIRAIIIEDEKPAIEELKYVLSKYNFLNIVDVAMTGDVGYELVKKIQPEVVFMDINMPTENGISVSKKIKEFNKDINIIFITAYEQYALEAFEIDALDYILKPFDDKRIGVTIKRLQEKIDEKYKEEIPVMISDILNKLEKEEKTLKKIPCEYRGKIILIDTKNIYYCYTMEDKTYVKTNSEEYITHNTLKEIEKKTDLFRVHRSYIVNMDNIKELYSWFNGTYKLVMNDKEQSEIPVSRNNVKKVKEILGI
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MIKGWASPMSTVEALNKKLQQDEDWLRQFEANVTRSEQLRGNIERILNDFERHIDQLESNVFPMHEQNGKLQIKQMNIQKLLKTIDATIQFYGKSGELESAIRGRKFWYNQRIACFSARTSRKMRARDGSPSLDLGAYLEQMEHLQQAVAFFHAHPNYGTQLDNMKITLESGCVLLEKEYRNVVHANSHAAEPQAVIDCLDEQYELMQSRAREIHTLSNVDKVARLGEWLLKHGRSSRFLQHYSSIRGDLMVRTLTTIFQAHSMQAITDKIAGLSASANTSFTRSNASFNSKNISTTSLKKATRFAPDQGMGTREAEGADTECGLLVTAAFVALVYVEEGILDRAVPVFERRAQVHRDLLKAPLNYVIKVLTRSVQESEGSLAALLPLLRFVAARHVQLSTIAENAHLEQPYQSAFRALTLRCSSYIADYFERGAVGKIGFCGVAAALRTTFERGAGTEVKFVPSDGNVHPVTASTLNTLYLLSHYRQVVTNQVLSLNAQPNEPVALLMPKLFAKMLSHLGHVLRARAETYDDPTLAAIFSLNNSNYIAKALGDESSGLLPVLREQNAHILQFYLDAIQKHISEYMASWYPVLQTITSVDQMHPEDRTAMRNAITAFTREFEQTVSAQRGYCVTDPILADQVRVKVKAAVVPMYAKLYNKANALTEAASLSSHLRYTEESLDVNIDRLFDVAV
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MATKLASFIFRIGSILAVTPSYNTGEMTFVRKLYGLLFATIMTISIVVSTINRDFYRSIPTVPAIERTILDINMALLNYYLIFSVMFWKRIQWKDLIKKIHVLVDKNCFPFAVIFLLIQIFDLVFLITAFCFKLDLMGLEYVKKYNFVYVQDYMVFFFNSIMSFILSIVLLKYKQLYNSLLHTYRIQTIEKVQKNLRFLKVVNESFNDIFEWPIFLIISYTTLHLLCHFDNIFMTSMSHKYGSVPTKKIVADLSILFFCFFGTAGMILLCDAVLIEAEKVLTVSYKLTEFYEEKLYLTRVVLENFPSFSAAKFFNVNRSTLLKVLTSVIGFLIVFVQIRQV
The following text describes a protein:
Function:
Required for mitochondrial genome maintenance and mitochondrial DNA inheritance.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein.
Sequence:
MDKLTPSQWKVINKSYEPASTIKVIAGPGSGKTLTLLYKVLHLITVENIKPEEILIFSLTNKAVDSIIENLLSIFENSHTNKEIVHQIGCYTVHGLANRIVVENEGMINIIEEIGWRGLMKLLPPSKRTPHHFRSYKELEKVVKDYKLNNAKNNNPVIEKLVELMDNCKVMTNDDLIIRAKKYLELDSSDSDASSFTQDLRNKYKVVLIDEFQDLYPSLAPLITMICKGKQLIMFGDTNQSIYGFLGSNNEIMSQLDNLHPKNSTTVLKLFDNFRSTPEIISLASKIINRPLAEKQIIDDTDETPSELVRKLPSGVSPQIMTFDDLAAESEFIIDKITQLICSSAKFSDIAILSRTNSHLTAIASILKKYGIPYQKLKSQPDWMDDLRIQFLLDILKVCSLASDEKHNREFNTGDKWQSNFSILVTMSALKGIGDASIQALYKACSLKNLSIWKYLTMVPNFEWPLGLSIKKKMENYTSNLYEMIENDQVHQLDDPMELLEKVASITNNLNLNPTYFQSLSDAQSSLEFKTHLQEMAQVMKVSKSNKPPGISFVKWFLETYFDQTMVFHQSQQALQTTGPGTVKLSTIHSAKGLEFPIVFLTNGSMSNFPMDTNALYVGITRARNLLYMCNMKHERLVSKSSPYSRNIMSNNLFWTYYNKDLKRSVCDVKVTHGYNVQRYNQLRKNFGFYRAYSSLRGCKSVFRRI
The following text describes a protein:
Function:
Forms the portal vertex of the capsid. This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel. Binds to the terminase subunits to form the packaging machine. Necessary to ensure correct procapsid size during capsid assembly. Once the capsid is packaged with the DNA, the terminase complex is substituted by the connector proteins gp15.
Subcellular Localization:
Virion. Note=Occupies the twelfth vertex of the capsid.
Sequence:
MNLFGKVVSFSRGKLNNDTQRVTAWQNEAVEYTSAFVTNIHNKIANEITKVEFNHVKYKKSDVGSDTLISMAGSDLDEVLNWSPKGERNSMDFWRKVIKKLLRAPYVDLYAVFDDNTGELLDLLFADDKKEYKPEELVRLTSPFYINEDTSILDNALASIQTKLEQGKLRGLLKINAFLDIDNTQEYREKALTTIKNMQEGSSYNGLTPVDNKTEIVELKKDYSVLNKDEIDLIKSELLTGYFMNENILLGTASQEQQIYFYNSTIIPLLIQLEKELTYKLISTNRRRVVKGNLYYERIIVDNQLFKFATLKELIDLYHENINGPIFTQNQLLVKMGEQPIEGGDVYIANLNAVAVKNLSDLQGSRKDVTSTDETNNQ
The following text describes a protein:
Function:
Probably acts as an adapter for ATPase cdc-48.1 and/or cdc-48.2, conferring substrate specificity. Involved in the lysosomal clearance of cellular material in diet restricted conditions.
Sequence:
MNSFKKFLNKKRVQNHFKKSGEGVRLSSGESSSQPSAHAGAAQGGQIDRVAAADIAAQAAFKRMQKNEPQQNAGKRRIQMIAKRELEEERRQVEDLNISGTSSLQQPDREQHLEHSSAISRVLYTSELLGEHHIRSKADLLEDIKNFLSDQISEADDENDKVIAAVLMLYSLNKKHPKETAIETICKYCQNILEHPGEDKYKSIRLGNKAFQERVASVVGGRAFLEAVGFTEKSEGEDKFLVFTKPSDVHLVEALEALKDGQAVPIKVARNLEIFKLKEGQKPKAPKLADDFYNLSTAELKAEQRNKEMQVERMLTLRTKEMRQKDEQMTNYRYKYTLIRVRLPGNLLMQGVFGCHEPFSAVRVFVASTLSDALSTSEFTLRDAASQLVEDESASLAQLSLAPAALLHVVFAENLSDYGQIVADEHIEIIQELEASD
The following text describes a protein:
Function:
Plays an essential role in generating the deoxyribonucleotide precursors dATP and dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the nucleoside is less strict. Both 2-deoxyribose, ribose, and arabinose nucleosides are phosphorylated, although the 2-deoxyribonucleosides are preferred. The phosphate donor specificity is dependent on the deoxyribonucleoside substrate, but GTP is efficient with both deoxycytidine and deoxyadenosine. Only nucleoside triphosphates can act as phosphate donors.
Sequence:
MKEHHIPKNSIITVAGTVGVGKSTLTKTLAKRLGFKTSLEEVDHNPYLEKFYHDFERWSFHLQIYFLAERFKEQKTIFEAGGGFVQDRSIYEDTGIFAKMHADKGTMSKVDYKTYTSLFEAMVMTPYFPHPDVLIYLEGDLENILNRIEQRGREMELQTSRSYWEEMHTRYENWISGFNACPVLKLRIEDYDLLNDENSIENIVDQIASVIHDNQKK
The following text describes a protein:
Function:
Regulates cell determination; development of ommatidia and optic lobe. Is a signaling molecule involved in the process of axon pathfinding in the eye. Part of the Ras pathway regulating programmed cell death in pupal eyes; activated by lozenge (lz). Antagonist for the Egfr receptor (gurken). Inhibits Egfr signaling without interacting directly with the receptor, but instead by sequestering the Egfr-activating ligand spitz (spi).
Subcellular Localization:
Secreted.
Domain:
The three two-fingered repeats tightly encircle spi, providing the basis for it's sequestration. The first repeat harbors a 120 AA insert specific to drosophilidae.
Sequence:
MPTTLMLLPCMLLLLLTAAAVAVGGTRLPLEVFEITPTTSTADKHKSLQYTVVYDAKDISGAAAATGVASSTVKPATEQLTVVSISSTAAAEKDLAESRRHARQMLQKQQQHRSIIGGKHGDRDVRILYQVGDSEEDLPVCAPNAVCSKIDLYETPWIERQCRCPESNRMPNNVIIHHHSHSSGSVDSLKYRNYYEREKMMQHKRMLLGEFQDKKFESLHMKKLMQKLGAVYEDDLDHLDQSPDYNDALPYAEVQDNEFPRGSAHMRHSGHRGSKEPATTFIGGCPSSLGVEDGHTIADKTRHYKMCQPVHKLPVCTHFRDYTWTLTTAAELNVTEQIVHCRCPRNSVTYLTKREPIGNGSPGYRYLFACSPLTRLRCQRKQPCKLFTVRKRQEFLDEVNINSLCQCPKGHRCPSHHTQSGVIAGESFLEDNIQTYSGYCMAND