lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalytically inactive protein kinase that acts as a scaffold protein. Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth. Promotes Src family kinase (SFK) signallig by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism. Acts as a critical coactivator of Notch signaling (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Cell junction, focal adhesion. Note=Colocalized with NOTCH1 in the nucleus.
Domain:
The dimerization region encompasses helices both from the N- and C-terminal of the protein kinase domain.
Sequence:
MSACSDFVEHIWKPGSCKNCFCLRSDHQLTAGHPKARASSLPAGARLPARPEICRLEDEGVNGLAYSKPTIAVKPTMMTSETADLWTEASLSAEVPKVNWRRTPGKLLLQKQEDGPIVYLGSFRGMQKAAGPLACTDSNSRCPPAYTMVGLHNLEARVDRNTALQPVNFQEEKAGREELPSAQESFRQKLAAFTGMTSSCLKGPRPCTSPQPLRESLPSEDDSDQRCSPSGDSEGGEYCSILDCRPESRDAVHNTEGSGRRRGDCSPICWEQGTCTRPTEEEKQALNFPRECCGQGSTANPPHLGPKKPSLNSEAASSSDGLSCGSSRSGANSPFAPHLENDYCSLVKEPTSVKQQDSGCHLVNSGKYVGQAVDLQPPALPREAVQPEPIYAESAKRKKAAPVPQRPEPKKEQVSSGQVWTGDTWSQKTPSGWSQEREGPNAAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPRGSLNQDLHGSGEEPLVVQGLSSRESHPHNMTENSSKEKPAIPPKLSKSSPGGSPVSPAAPPLTDHSDGNTSGSSVGSQPSSRVPTNLTSSCQTNGVAAGDPAKCPPQANSSVLDQRRPRYQTGAWSRQCRIEEEEEVGQELLSQSWGRELENGIADHSNSSTWHRLHPIDGASGQNGKTNSGMSKSASFAFEFPKDRGRLESFSPPPPPPKSRHLLKMNKSSSDLEKVSQSSAESLSPSFRGAHVSFTTGSTDSLASDSRTCSDGGPSCEATHSPTISGKKLFAPVPFPSGSTEDVSPSGPAQPPPLPQKKIVSRAASSPDGFFWTQGSPKPRTASPKLNLSHSETNVCAHDEPPLSYSLNSGNHPHHVFSSSEPLEKAFKGSVPWAPALGPANSKGGCGSPNLQGRAATSTSSSQLSVSSQASTGSSQLQLHSLLSSISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGLKTELRFDENSWSLFKLICNKPCCDSGDAIYYGATCSKDPDSIYAVKICKTPEPKSASYCSPSVPVHFNIQQDCGHFVASVPSSMLAFPDTSSKDPAPAAPSHTPAQEQDCVVVITREVPHQTASDFVRDSVASHRAEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCNPQSSPGPSANPSVPTTTSRCPSAAPAATTACQGGPGEKHLPRLIISNFLKAKQKPGGTTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSPGLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVEQPCPSEEVLCNTLHNWIDMKRALMMMKFAEKAVERRRGVELEDWLCCQYLASAEPGALLQSLKLLQLL
The following text describes a protein:
Function:
Positive regulator of sigma-F (SigF) activity. Binds to anti-sigma-F factor RsbW (UsfX) preventing its binding to SigF, thus activating transcription.
Sequence:
MSAPDSITVTVADHNGVAVLSIGGEIDLITAAALEEAIGEVVADNPTALVIDLSAVEFLGSVGLKILAATSEKIGQSVKFGVVARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR
The following text describes a protein:
Function:
Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.
Miscellaneous:
MISCELLANEOUS: Present with 6190 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTGYPDVAAFDLDYTIWPCYCDTHLHGPFKPVKSSNGEVLTIICRDGYELTIYKDIPRILGDLKDNGVKLMTASRTWAPEIAQEILKIFKVKYAGVVTPLANLFDEFQWGERSKIGHLRDGLKDLYNTSDLKSKKICLFDDESRNKEVEKYGVKFVYVRDPENGPSWKLYQDYLSGKV
The following text describes a protein:
Function:
Regulates arginine biosynthesis genes.
Subcellular Localization:
Cytoplasm.
Sequence:
MKISKKRRQELIRKIIHEKKISNQFQIVEELKKYGIKAVQPTVARDLKEIGAVKIMDESGNYVYKLLDETPVIDPWKELKRNFKSFVESIDRAGNLIVIKTIPGTASGIARVIDRLDIDEIVGTLAGDDTIFVAVRDPESCEKIVEKLSSIL
The following text describes a protein:
Function:
Catalyzes the transfer of sulfur from 3-mercaptopyruvate to a thiol-containing acceptor to form an intramolecular disulfide releasing hydrogen sulfide and pyruvate.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal region is the non-catalytic domain; the C-terminus contains the active-site cysteine residue and the CGSGVTA motif probably responsible for substrate specificity; Contains two rhodanese domains with different primary structures but with near identical secondary structure conformations suggesting a common evolutionary origin. Only the C-terminal rhodanese domain contains the catalytic cysteine residue (By similarity).
Sequence:
MSSAQLLTAQQLAARLSEPDLLVLDCRFALEDPSYGARVYQENHIPGAHFADLERDLSAPVRKGVTGRHPLPDPAELALKLQAWGLRQDSQVVLYDDGPGAFAARAWWLLHWLGKRDGVYLLDGGLAAWKAAGLALTNGESSLRPGDFQGQPDASLLIDAATLQAQLGQPGLALLDARAQPRFRGEVEPIDPVAGHIPGAQCAAFTDNLGSDGRFLPPEQLHQRFSALLRGRPVDELVAYCGSGVTACHNLFALSLAGFPLPRLYAGSWSEWITDPRRPVATGD
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.
Sequence:
MLDPSEKGSSSEDQTKKSPEWISPKGSPNQSIETKKVCADCGTSKTPLWRGGPAGPKSLCNACGIRSRKKRRAILGLNKGEDKKSKKGNINGNSYNRKSSSSNTKNLGDNLKQRLLSLGKEVLMQRSKVEKQRSKLGEEEQAAVLLMALSYGSVYA
The following text describes a protein:
Function:
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
Subcellular Localization:
Cytoplasm.
Sequence:
MDQDKYLSSYDYHLPADCIAQTPAVPRDHSRLLVVKDPFTVDHQHFYDLGNYLKPGDLLVLNDTKVMPARLHGQKENGVAVEILLLTECTENQWIALVKPGKRLKLGAKVKFPARDGEKPDLWATILQRDDATGGRLLEFVLEPGQRLWDVLPDYGEIPFPPYIGDRQATNDQYQTIYAEKLGAVAAPTAGLHFTEELFTKLAQQGVQTAKVTLHVGIGTFRPVEAENILDHVMHQEWIDVPPTTVEVIEKTRASGGRIFAVGTTVVRCLEGMAQESDFPRQPLQPFRGQTDLFIYPGYQWRLVDGLITNFHLPKSSLLMLVSALISRPRLMAIYETAIAKGYRFYSFGDAMVILPEACRGQEKIR
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MLRAAAAAFGLAHRPVAVVGRDAELSVLADVLSLGFADGTAHGLFLSGNPGTGKTLCLRHVCRLSPSLQGALQIWINAALLARPEQVYQELHCRIFSQSRRMAPLRAKKALEAHFQRQPQTKRNTLIVIDEVDHLQSKNDQIFYFLYNTLLTAPHPLLFVSIANSLYFPYTDRIASRLSGITKLEFPAYSPETFTSIIKARIQELSAEYTEVNQLFQNDAVLKLLVGRVLHRGGDIRTALQFTFRTIARTVAEGLTTIPLRIVDQITCADLSESALCATELTKLEHAILKTTARDNTTIGSIIELGHGGLGIQQPLCTNEPPSLNLIERAISRLCTSGLILREPSADGYNHLTESDELYKSTDKLYINVVLD
The following text describes a protein:
Function:
Appears to lack serine protease inhibitor activity in vitro when tested with bovine pancreatic alpha-chymotrypsin and elastase. Involved in cuticle biosynthesis.
Sequence:
MVSIHNSFILLMLMISICFCEKCLTNEECDLKWPDAICVRGRCRCSENTIRKKSASREWVCLATNDATGNSGPPLTCPTPEGAGYQVMYRKDGEPVKCSSKKKPDTCPEGFECIQGLSILGALDGVCCPDRAKTCVHPIFDHPDDGYLSRWGFDGEQCIEFKWNPERPSSANNFKTRAHCEDYCIGSINGITNYHQSNFHLF
The following text describes a protein:
Function:
Downstream effector of TOR signaling pathway. May be involved in adaptation of plant to cold or high-salt conditions. Mediates the phosphorylation of MRFs (e.g. MRF1).
Domain:
The activation loop within the kinase domain is the target of phosphorylation.
Sequence:
MVSSQCSVANKNQTGKPFQKHLSLSISPPKSVLGDNLELQFSDVFGPMPEANSEEACDVAYDEPAVVYSRSHSLVGPSLVVSHSLKMNKLTLRETEDSVDLVECVEGESIKENDEFSGNDDTDSEKSPEEVSGVVGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVSGRQCIANFDKCWTDMSVLDSPASSPNSDAKANPFTNFTYVRPPHSFLHRTTSNL
The following text describes a protein:
Function:
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
Sequence:
MSSEKEYVEMLDRLYSKLPEKGRKEGTQSLPNMIILNIGNTTIIRNFAEYCDRIRREDKICMKYLLKELAAPGNVDDKGELVIQGKFSSQVINTLMERFLKAYVECSTCKSLDTILKKEKKSWYIVCLACGAQTPVKPL
The following text describes a protein:
Function:
Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities. Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation. At the mRNAs 5' end, methylates the ribose 2' OH group of the first transcribed nucleotide, thereby producing a 2'-O-methylpurine cap. At the 3' end, functions as a processivity factor which stimulates the activity of the viral poly(A) polymerase OPG063 that creates mRNA's poly(A) tail. In the presence of OPG102, OPG063 does not dissociate from the RNA allowing tail elongation to around 250 adenylates.
Subcellular Localization:
Virion.
Sequence:
MFFDQRRVLTENAPRRPYQNNASTASFECPLLKGLHYGQRKLMLSEVEFLVQISMHIKRRCSGAAPKRVLVVYAGAACGLHLPFLFSLFPALDFVLIDPAPFCPRVKEIASKEGSCVLELIEDLCTAELCLRIRRTYHETHDIFLVSDIRSGEPTGMSLNQEHTDMIQQDNNAQREWCFSLEVEAAMLKFHPPYPAAKDSDPANYKAQDATVEEYTYLDGTQLLGVWAPKSSSEVRLIVVGPFKRGYAAPTRRYYCTVHEEQCYAYNTDNRYEKDCTAERLILEAYLSAFPGAYQSVEPLSKELSEQLEYPLFCPLEPGFTEQHARWVTLLYSTRKPAALQYFDLLKNDMSVEQVAGLVTKYKDCCEIPAGVKVGDIELTPHFWSVFAAGDFAVVYCFPFVRWEWKRHAHRRQPDKRRDDGRKNHRRFAGKKRTANTA
The following text describes a protein:
Function:
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MDQNFKLLDQAIKRFENFPNQGTLFYDITPVFSNPQLFNFVLTQMAQFIKAINAEAIVCPEARGFIFGGALASKTQLPLVLVRKANKLPGQLISASYDLEYRKHAVLEMSTTSLIQANNAKRCVIVDDVLATAGTVAAIDQLLKQLNGETVGYCFLIELKKLNGKAKLQPNVVSKILLHY
The following text describes a protein:
Function:
Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule-associated proteins such as MAP65-1.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MQDLFGSVRRSLVFRSTTDDENQENHPPPFPSLLADKITSCIRKSMVFAKSQSPPNNSTVQIKPPIRWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELLKHPFVTGKQKESASKDLTSFMDNSCSPLPSELTNITSYQTSTSDDVGDICNLGSLTCTLAFPEKSIQNNSLCLKSNNGYDDDDDNDMCLIDDENFLTYNGETGPSLDNNTDAKKSCDTMSEISDILKCKFDENSGNGETETKVSMEVDHPSYSEDENELTESKIKAFLDDKAAELKKLQTPLYEEFYNGMITCSPICMESNINNNKREEAPRGFLKLPPKSRSPSQGHIGRSPSRATDAACCSKSPESGNSSGAPKNSNASAGAEQESNSQSVALSEIERKWKEELDQELERKRREITRQAGMGSSPRDRSLSRHREKSRFASPGK
The following text describes a protein:
Function:
Catalyzes the conversion of geranylgeranyl diphosphate to the phytoalexin precursor ent-copalyl diphosphate.
Miscellaneous:
MISCELLANEOUS: 2 different ent-CDP synthases exist in rice, one being involved in gibberellin biosynthesis and the other in phytoalexins biosynthesis. Phytoalexins are diterpenoid secondary metabolites involved in the defense mechanism of the plant and produced in response to attack (by a pathogen, elicitor or UV irradiation).
Subcellular Localization:
Plastid, chloroplast.
Domain:
The Asp-Xaa-Asp-Asp (DXDD) motif is important for the catalytic activity, presumably through binding to Mg(2+).
Sequence:
MQMQVLTAASSLPRATLLRPAAAEPWRQSFLQLQARPIQRPGIMLHCKAQLQGQETRERRQLDDDEHARPPQGGDDDVAASTSELPYMIESIKSKLRAARNSLGETTVSAYDTAWIALVNRLDGGGERSPQFPEAIDWIARNQLPDGSWGDAGMFIVQDRLINTLGCVVALATWGVHEEQRARGLAYIQDNLWRLGEDDEEWMMVGFEITFPVLLEKAKNLGLDINYDDPALQDIYAKRQLKLAKIPREALHARPTTLLHSLEGMENLDWERLLQFKCPAGSLHSSPAASAYALSETGDKELLEYLETAINNFDGGAPCTYPVDNFDRLWSVDRLRRLGISRYFTSEIEEYLEYAYRHLSPDGMSYGGLCPVKDIDDTAMAFRLLRLHGYNVSSSVFNHFEKDGEYFCFAGQSSQSLTAMYNSYRASQIVFPGDDDGLEQLRAYCRAFLEERRATGNLMDKWVIANGLPSEVEYALDFPWKASLPRVETRVYLEQYGASEDAWIGKGLYRMTLVNNDLYLEAAKADFTNFQRLSRLEWLSLKRWYIRNNLQAHGVTEQSVLRAYFLAAANIFEPNRAAERLGWARTAILAEAIASHLRQYSANGAADGMTERLISGLASHDWDWRESKDSAARSLLYALDELIDLHAFGNASDSLREAWKQWLMSWTNESQGSTGGDTALLLVRTIEICSGRHGSAEQSLKNSADYARLEQIASSMCSKLATKILAQNGGSMDNVEGIDQEVDVEMKELIQRVYGSSSNDVSSVTRQTFLDVVKSFCYVAHCSPETIDGHISKVLFEDVN
The following text describes a protein:
Function:
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions. Within the MPT complex, the GEL subcomplex may mediate insertion of transmembrane regions into the membrane. In addition to its role in multi-pass membrane insertion, RAB5IF/OPTI also acts as an assembly factor for mitochondrial respiratory complexes.
Miscellaneous:
MISCELLANEOUS: [Isoform 4]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MSGGRRKEEPPQPQLANGALKVSVWSKVLRSDAAWEDKDEFLDVIYWFRQIIAVVLGVIWGVLPLRGFLGIAGFCLINAGVLYLYFSNYLQIDEEEYGGTWELTKEGFMTSFALFMVCVADSFTTGHLDHLLHCHPL
The following text describes a protein:
Function:
Key enzyme of fatty acid beta-oxidation. Able to isomerize both 3-cis (3Z) and 3-trans (3E) double bonds into the 2-trans (2E) form in a range of enoyl-CoA species, with a preference for (3Z)-enoyl-CoAs over (3E)-enoyl-CoAs. The catalytic efficiency of this enzyme is not affected by the fatty acyl chain length.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MRRVISSSLTRGAGTLGVVSGLFQLTQYRFQWQPLPGVPPQLRVAPQGRHQDLNAAHAGSKHSDDAQPEFVPPKKPTEVPKLVRINTNEKGITNVQLARAPVNSMSLELFQELNQWMLWLGCNEETKAVIISSAIPTVFSAGLEFSEVHNPKPDRIAVFWQSFQEMWRILDTFPKPIIAAITGNSPAAGCIIAMGCDYRVMARGPKGNTNNNRLYRIGLNETKLGLVPPPWTVSAYAYLLGSRQAEEMLQLGETPVADDARNLGLIDEVAADEERAIEVAYQQAERFLSVPQEARRVSRDMARCEYLRLLATEDDRNYDTEFFTQYMLRPEVQKNLESYLERLKSRSRK
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MMMNEFVLFGLIPGFVLRLGLICYSVYHDNRSALKYTDIDYQVFSDAARALLSGPNGSAWFFGSPYDRATYRYTPLLALILTPNEFIHPCWGKALFGSADLVIGILLYRLCPRGHSAASHGRLVSLIWLLNPFVINISTRGSSESLLGVVIIGFLYLAEHNKWDAAAVLLGVAVHLKLYPFIYATAVWARLAQHPHSRFGWLSISRSQVRFGVISLAAFSVLNLLMYIIWGQEFIESSYLYHLRRLDHRHNFSPYFYPIYLRFTSVLAEQSPMISILHHPLVSFIPQMSLTLALGFHYGAQDLPFACFIQTYVFVLFNKVVTSQYFMWYLWFIPLIVRHIKLSKPQSIGVAVIWVSTQVLWLSQAYRLEFLGEPQFRAVWLSSIGFLIGHSWIIGILILGFSPASSSIISSSDNGLKLKKT
The following text describes a protein:
Function:
Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell. Protects cells against the natural plasmid-encoded toxins microcin B17 (MccB17) and CcdB, and synthetic quinolones. Can also protect cells against alkylating agents that act independently of DNA gyrase, suggesting a more general role in protecting cells against DNA damage.
Subcellular Localization:
Cytoplasm.
Sequence:
MNYEIKQEEKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVPKEWVAVYYDNPDETPAEKLRCDTVVTVPGYFTLPENSEGVILTEITGGQYAVAVARVVGDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH
The following text describes a protein:
Function:
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
Subcellular Localization:
Cytoplasm.
Sequence:
MTQHLTAETLRKDFLAVFGQEVDQTFFSPGRINLIGEHTDYNGGHVFPVAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGVLHFLQEAGHVIDKGFDFYVYGNIPNGSGLSSSASLEILTGVVAEHLFDLKLERLDLVKIGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTNKRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRARHAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEGVLGARMTGAGFSGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
The following text describes a protein:
Function:
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Sequence:
MAWWNKLFGDPQERKVKKYQPRVAEMNALEAEVAALSDDQLRAKTAVFQKRVADQLQGVDLDALEIRERRRRIDVALDGVISEAFAVVREAAKRVIGLRHYDVQLIGGLVLHEGQIAEMKTGEGKTLVATLPAYLNALTGRGVHIVTVNDYLARRDSEWMGQVHRFLGLSVGLIQQSMTPSERAQNYAADITYGTNSELGFDYLRDNMATNAGELVQRSFNYCIIDEVDSILVDEARTPLIISGMVAKPAEKYMRANEVATALERNTHYEVDEKQRNVTLTDEGFIAAEQMLSTEDLFSPRDPWAHFVFNAVKAKELFNKDVQYIVRNDEVVIVDEFTGRVMPGRRWSEGLHQAVEAKEMVTIQNETQTMASITYQNFFLLYPKLAGMTGTALTEEAEFGKIYSLEVTAIPTNRKVVRTDMSDQVYKTENGKWQSVAAEIAEMNKNGRPVLVGTTSVEKSEVLSALLKEKGIAHNLLNAKPENVERESEIVAQAGRKGGVTIATNMAGRGTDILLGGNPEYMARLKLKEVLFPALVIDDEDAFSPMMRLLNNGNSRGTGFAATSKKKALPKAEIFPCELSESTKQQLKAAVDYAVAMLGADSQPALQVEELIAVASEKGPTDDPVIQHLREIYRAIYKEYQVVTDREHDEVVKLGGLHVIGTERHEARRVDNQLRGRSGRQGDPGSTRFFLSLGDNLLRIFGGERVAGLMEAFKVEEDMPIESGLLTKSLENAQRKVETFYYDQRKQVFEYDEVMNNQRKAIYAERRRALEGQDLSAVVREYIDQTVDEIVRAHVNAERPPEEWELPALIQDLQQLIPLLENQLDAVKLGEFSAVELEEDLKSQALLAYETREEYINAIQPDLMREAERYFILNQIDTLWREHLQQMDSLREMIGLRGYGQKDPLIEYKNEGYELFLQMLVEVRRNVVFALYHFQPQYNPPIDPDYVDSEYV
The following text describes a protein:
Function:
Converts 3-hydroxybenzoate (m-hydroxybenzoate), and to a lesser extent p-hydroxybenzoate, to 3,4-dihydroxybenzoate (protocatechuate). Also acts on a number of analogs of 3-hydroxybenzoate substituted in the 2, 4, 5 and 6 positions.
Sequence:
MQFHLNGFRPGNPLIAPASPLAPAHTEAVPSQVDVLIVGCGPAGLTLAAQLAAFPDIRTCIVEQKEGPMELGQADGIACRTMEMFEAFEFADSILKEACWINDVTFWKPDPAQPGRIARHGRVQDTEDGLSEFPHVILNQARVHDHYLERMRNSPSRLEPHYARRVLDVKIDHGAADYPVTVTLERCDAAHAGQIETVQARYVVGCDGARSNVRRAIGRQLVGDSANQAWGVMDVLAVTDFPDVRYKVAIQSEQGNVLIIPREGGHLVRFYVEMDKLDADERVASRNITVEQLIATAQRVLHPYKLDVKNVPWWSVYEIGQRICAKYDDVADAVATPDSPLPRVFIAGDACHTHSPKAGQGMNFSMQDSFNLGWKLAAVLRKQCAPELLHTYSSERQVVAQQLIDFDREWAKMFSDPAKEGGQGGVDPKEFQKYFEQHGRFTAGVGTHYAPSLLTGQASHQALASGFTVGMRFHSAPVVRVSDAKPLQLGHCGKADGRWRLYAFAGQNDLAQPESGLLALCRFLESDAASPLRRFTPSGQDIDSIFDLRAIFPQAYTEVALETLPALLLPPKGQLGMIDYEKVFSPDLKNAGQDIFELRGIDRQQGALVVVRPDQYVAQVLPLGDHAALSAYFESFMRA
The following text describes a protein:
Function:
Required for the ubp9 recruitment to septa and cell tips but also for its enzymatic activity at these specific locations.
Subcellular Localization:
Nucleus. Cytoplasm. Cell tip.
Sequence:
MQTMSSGIARPVLFLTAREGEYVLKDEFQLGSSSRSTPQITGSPLDPNTPVKRLFFMRINIAQFSRWDYPYPREYIEELKKIHGVHHVEENRDVPSILENYRNSKRKSHNFSSSNTPYLKLHRPASRAGAPLINAKSFISSLTFHDNIVRSFQPSIHGKTFVFANHEKSFYWLDVSAANSHSALLKMEFPRASPVCHDINSFTKSPKGLDVIIGFDTGDVLWYDPINFKYLRFNKNGQLNSSSVTAIKWVAGKDSQFLVSFRNGWLVLYDKYRHEQPLHIVVPEKNLKSLYLSSPGTFNILISINHRDDRKLNPVACYAFSKSPINGFCFSPDYQYLALVSERGTLKLFDFVKEHVLDVFHSYFAGLTCVTWSPDGKFIAIGGKDDLVSIYSFPLRKLVARCQGHKSWVTDVIFDAWRCDDDNYRIASVGLDRKLLLWDFSVSAIHRPKSAVYYVNHHSNNSKPAISDFDDVGDLTMGSEIDNSNYVNGDITIHPTLSRSLIPVISPITIYDVDDSPLSSVFFDPDCMITCATNGRIRTWQRP
The following text describes a protein:
Function:
Transcriptional modulator with roles in meiotic regulation and silencing.
Miscellaneous:
MISCELLANEOUS: Present with 3750 molecules/cell in log phase SD medium.
Sequence:
MAKSKSSQGASGARRKPAPSLYQHISSFKPQFSTRVDDVLHFSKTLTWRSEIIPDKSKGTLTTSLLYSQGSDIYEIDTTLPLKTFYDDDDDDDNDDDDEEGNGKTKSAATPNPEYGDAFQDVEGKPLRPKWIYQGETVAKMQYLESSDDSTAIAMSKNGSLAWFRDEIKVPVHIVQEMMGPATRYSSIHSLTRPGSLAVSDFDVSTNMDTVVKSQSNGYEEDSILKIIDNSDRPGDILRTVHVPGTNVAHSVRFFNNHLFASCSDDNILRFWDTRTADKPLWTLSEPKNGRLTSFDSSQVTENLFVTGFSTGVIKLWDARAVQLATTDLTHRQNGEEPIQNEIAKLFHSGGDSVVDILFSQTSATEFVTVGGTGNVYHWDMEYSFSRNDDDNEDEVRVAAPEELQGQCLKFFHTGGTRRSSNQFGKRNTVALHPVINDFVGTVDSDSLVTAYKPFLASDFIGRGYDD
The following text describes a protein:
Function:
May regulate active versus storage forms of cytokinins, and could have an impact on seed growth. Can also use UDP-xylose to catalyze the formation of O-xylosylzeatin but at much lower affinity.
Sequence:
MALNDKSIPHETKVVVLLIPFPAQGHLNQFLHLSRLIVAQNIPVHYVGTVTHIRQATLRYNNPTSNIHFHAFQVPPFVSPPPNPEDDFPSHLIPSFEASAHLREPVGKLLQSLSSQAKRVVVINDSLMASVAQDAANISNVENYTFHSFSAFNTSGDFWEEMGKPPVGDFHFPEFPSLEGCIAAQFKGFRTAQYEFRKFNNGDIYNTSRVIEGPYVELLELFNGGKKVWALGPFNPLAVEKKDSIGFRHPCMEWLDKQEPSSVIYISFGTTTALRDEQIQQIATGLEQSKQKFIWVLREADKGDIFAGSEAKRYELPKGFEERVEGMGLVVRDWAPQLEILSHSSTGGFMSHCGWNSCLESITMGVPIATWPMHSDQPRNAVLVTEVLKVGLVVKDWAQRNSLVSASVVENGVRRLMETKEGDEMRQRAVRLKNAIHRSMDEGGVSHMEMGSFIAHISK
The following text describes a protein:
Function:
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.
Sequence:
MAGLEQLATVDQLIMRMETESSETRHKIFVENSAGKKLFYPGTVSGRFRRNLYLSLQAFNLKILDNLKNEVIHVHRPGLCCSLSCGLSLDLFILAPPDTFVGKIEEKCRICGTKFGIKDASGKKVFVIKGPCCVRCSKNVELKILAADEKTQVGFISKQAKAKCLRMSFPKDMDVEMKAVMVGACFLIFATFFNVNMSRLWQYHFS
The following text describes a protein:
Function:
Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Synapse, synaptosome. Lysosome.
Domain:
C2 domain 1 is involved in binding calcium and phospholipids.
Sequence:
MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRRGPGPEGGGGGGGTGCGEAPAHLAPLALAPPAALLGATTPDDGAEVDSYDSDDTTALGTLEFDLLYDQASCMLHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYSGITDDDITHKVLRISVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLPSPSSMSAALRGISCYLKELEQAEQGPGLLEERGRILLSLSYSSRRHGLLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEAQKHWNDCLHQPDTALERWHTLTSELPPAAGAYPLA
The following text describes a protein:
Function:
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. Modulates cold stress- and osmotic stress-responsive gene expression by acting as key regulator of abscisic acid (ABA) biosynthesis.
Sequence:
MEAFLKEFGDYYGYPDGPKNIQEIRDTEFKRLDKGVVYLDHAGSTLYSELQMEYIFKDFTSNVFGNPHSQSDISSATSDLIADARHQVLEYFNASPEDYSCLFTSGATAALKLVGETFPWTQDSNFLYTMENHNSVLGIREYALAQGASACAVDIEEAANQPGQLTNSGPSIKVKHRAVQMRNTSKLQKEESRGNAYNLFAFPSECNFSGLRFNLDLVKLMKENTETVLQGSPFSKSKRWMVLIDAAKGCATLPPDLSEYPADFVVLSFYKLFGYPTGLGALLVRNDAAKLLKKTYFSGGTVAASIADIDFVKRRERVEEFFEDGSASFLSIAAIRHGFKLLKSLTPSAIWMHTTSLSIYVKKKLQALRHGNGAAVCVLYGSENLELSSHKSGPTVTFNLKRPDGSWFGYLEVEKLASLSGIQLRTGCFCNPGACAKYLELSHSELRSNVEAGHICWDDNDVINGKPTGAVRVSFGYMSTFEDAKKFIDFIISSFASPPKKTGNGTVVSGRFPQLPSEDLESKESFPSHYLKSITVYPIKSCAGFSVIRWPLCRTGLLHDREWMVQGLTGEILTQKKVPEMSLIKTFIDLEEGLLSVESSRCEDKLHIRIKSDSYNPRNDEFDSHANILENRNEETRINRWFTNAIGRQCKLLRYSSSTSKDCLNRNKSPGLCRDLESNINFANEAQFLLISEESVADLNRRLEAKDEDYKRAHEKLNPHRFRPNLVISGGEPYGEDKWKTVKIGDNHFTSLGGCNRCQMINISNEAGLVKKSNEPLTTLASYRRVKGKILFGTLLRYEIDEKRQCWIGVGEEVNPDIE
The following text describes a protein:
Function:
Involved in regulation of actin cytoskeleton organization and cytokinesis.
Subcellular Localization:
Nucleus. Nucleus, nucleolus. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=In living cells localizes to the cell cortex and nucleus. In formaldehyde fixed cells localizes to the nucleolus.
Sequence:
MSNKNPLNNSNGSNSSTIVNSDKFLVKIHSLSVSHTSKSSNIYLVGDFDQFKQFKTETKKSSSTHGSCIYNEFAMEFQYETKYIHKLDHKHFKICVYKKKSIGSDKYIGSFGVDLYTLATGPISHDVVFQKDNTGVGRLQFRLEMNHITDIQISFKSILLSNLMKQSNYQIDYSLNKINPLKSSIIENTICPSWYNQSSILMNISLKDLVDGSIFFNLKDTKSSKVIGELKLPVKSIFSFVEGDIKIVKTLLYNEKQNKICDACIEIQFNNIPQLAQLRGGIQTEQGIRGAESFFSGVPLPKIIGEISNASTSDGYSKEAQLQHVKLPDGWESRIDPVSGKVFYLNHNNKTTSWISPLEHAPVKKRTPTVVISNTTILDNNNNNNNNNNNNNNNNNNNNNNINNTNNIQQKQQAQQQPVQPPPQPVQQQVQQPQQKEKEKEKEINAEDYKISRPKKTPATPEEAAVIIQRTFRNHKKQSYNKTIRNSKTIIPPNNVQQQQPQQTEKPSIYQVFGQQIDQGLPNGWEVRQDQFGRVFYVDHINRATTWTRPTVKHPKQHQQATLVQQRK