lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Subcellular Localization:
Midbody, Midbody ring. Cell projection. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with CNTRL/centriolin at the midbody ring (By similarity). Localizes at the leading edge of migrating cells (By similarity).
Sequence:
MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIEELHRHLYIKSTSRVVQRNKEKGKMSSHGKDPSPGPLIDVSNIPTPRKFLDASQYSAAGGSSVREMNLQDVKEDLECDPEENSTLFMGILIQGLARLKKIPETVKAIKERLEQELKQIVKRSTTQVADSAYQRGESLTVDNQPRLLLELLELLFDKFNAVATAHSVVLGYLQDSVGTQLTQQEEIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLIEGGGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAKQCPLREFLTVYIKSIFLNQVLAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTVQDLMNLMHDLSAYSDQFLNMVCVKLQEYKDTCSTAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWTNMAQPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLAGRTKSAFSNLSTSQMLSPAQESHVNMDLPPVSEQIMQTLSELAKTFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAMEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGDQTTQNTRLQRLKEIICEQAAIKQATKDKKITTV
The following text describes a protein:
Function:
Hydrolyzes inulin-type beta-(2,1)-fructans and beta-(2,1)-linkages in branched fructans. Has low activity against beta-(2,6)-linked fructans. May play a role as a beta-(2,1)-trimmer during graminan biosynthesis.
Sequence:
MAQAWAFLLPVLVFGSYVTSLFFPSYISGPLCGGDGGGRSLFLCAQAPKDQDPSPAVSTMYKTAFHFQPAKNWMNDPSGPMYFNGFYHEFYQYNLNGPIFGDIVWGHSVSTDLVNWIGLEPALVRDTPSDIDGCWTGSVTILPGGKPVIIYTGGDKDQHQAQNIAFPKNRSDPYLREWIKAANNPVLRPDEPGMNSIEFRDPTTGWIGPDGLWRMAVGGELNGYSAALLYKSEDFLNWTKVDHPLYSHNGSNMWECPDFFAVLPGNNAGLDLSAAIPQGAKHALKMSVDSVDKYMIGVYDLQRDAFVPDNVVDDRRLWLRIDYGTFYASKSFFDSNKNRRIIWGWSRETDSPSDDLEKGWAGLHTIPRTIWLADNGKQLLQWPVEEIESLRTNEISHQGIELNKGDLFEIKEVDAFQADVEIGFELASIDDADPFDPSWLLDPEKHCGEAGASVPGGIGPFGLVILASDNMDEHTEVYFRVYKSQEKYMVLMCSDLRRSSLRPDLEKPAYGGFFEFDLEKERKISLRTLIDRSAVESFGGGGRVCITSRVYPAVLADVGRAHIYAFNNGSATVRVPQLSAWTMRKAQVNVEKGWSAI
The following text describes a protein:
Function:
May be involved in environmental stress response.
Sequence:
MGGGTEAFPDLGSHCQHFDXHSSFFLPSFTSIQSSVQVFCVEHRSCKSHECPKSDINSRKVLVCEICSMSIETTGCQGEDDKAILQKHEKSGDCDPKKKKKPTCPVKRCKEILTFSNTSTCKSCRIQVCLKHRFPADHACKRNSSLSQPSVNNKFLIALAARSGNDCGNKNRTSTSRPTTPSVKAC
The following text describes a protein:
Function:
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.
Subcellular Localization:
Nucleus.
Sequence:
MVGGRFVVDNYDDQSIVFEEDVFDKIEDLLDFDKLEDMQLINNHHHHHHHQHPEQQQQQQNQNQPINCFQEQHPWPPKSDFLSSFKCDIDVAELEWLSNFVEDSFSPTAEDVMLLPKVIHTDNGSAVTSFSYSSSSPTSSSSCSTAAIDKKAEETTVVRGRAPRSKRPRPHVPVPVPVPMPVVVVAPNPVLPDNEFKDEKRKKLKTSLSVSATNRNYGIDEREAEKQVVRKCLHCDIQKTPQWRAGPMGPKTLCNACGVRYKSGRLFPEYRPAASPTFVPDRHSNSHKMVVEMRVKSSHTKTTTPAIPSLPVSAKGCELLNYIK
The following text describes a protein:
Function:
Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity (By similarity). Displays mitochondrial GTPase activity (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MAAQLNPFRNAFRLPSKQRINWFPGHMTKGMRQIQQKLRNVDCIVEIHDARIPLAGRNSQFFDTITGSGVKPHILVLNKVDLLGAKQQKSVLQQLRRQQPELQHILFTNCKDQRNNGVLDILPLATRLVSESSRFNRTQAAEHNLMIIGVPNVGKSSVINVLRNVHLKKKSAARVGAEAGITRSVGERIKIQENPPVYMIDTPGILQPSIKDDEMGMKLALVGCLPDHIVGEDLIADYLLYWLNSHRKYDYVEMLKLSSGPSDDISAVLAEYAHREELFHKVKQYDGRVEVMTNLLAAARKFIHFFRSGQLGHMNLDEPSGFR
The following text describes a protein:
Function:
Potassium transporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHIHSLYLLEFWQWKTITLAYQTLGVVYGDLGTSPLYVYPTMNFKSPQGEDFLGTFSIIFWTLTLIGLAKYVFIVLHADDHGEGGTFALYSLLCQHLKTTIKGHKYGRMLSDSKLSHFSKTNEAESPTAFARFIERRKSAQRLLLFVAMLGTCMLIGDGILTPAVSVLSAMAGIATATPKINQSTVVWLSAAVLVALFLLQRFGTKCVSFVFSPIMAIWLITTPLIGLYNIVIHYPQIYKALSPHYIVTFFQRNGKDGWLALGGTVLCITGAEAMFADLGHFTKSSIQVAFAFMIYPSVLLTYAGQSAYLVRHPGDHREAFYKFLPRSIYWPMFVVSTLAAIVASQGLISAAFSIIKQSIALDYFPPVTMVHTSQDKEGQVYSPQVNYCLMVLCLAVLFGFQGGPEIGNAFGVAVIWVMLITSSLITLVMLIIWRTPVILALVYITVYGTLEGVYLSSVLTKLREGGWFPFGISVILALAMFSWHHGREKISDYEMINKVTVDSLDELFSRAAKQRVPGLCLFYTDLVHGVPPIMRHYVNNVRSLHQVIVFITIRYVPVRTVLPDERFILERCGYAGVYRCVAQYGYTDVLEGEEFVSDVIEALAIFVASREDHEELDSDGDGAALVSDLWRAKAAGAVHVMAKADFRMSEERSGWFERLVLDGIYRFLRNNCQMPVAALKIAPQNVIEIGMMYEI
The following text describes a protein:
Function:
Regulates ATP-dependent protein translocation into the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Domain:
The J-like region, although related to the J domain does not have co-chaperone activity.
Sequence:
MAKYLAQIVVMGMQVVGRAFTRALRQEFAASKVAAEARGRAGTESAAVSSLSGISLQEAQQILNVSKLTPEEIQKNYEHLFKVNDKGLGGSFYLQSKVVRAKERLDQEMEIQSKTHKPKEETTQT
The following text describes a protein:
Function:
Positive regulatory factor required for depression of the coregulated phospholipid biosynthetic enzymes. Also involved in the expression of ITR1.
Miscellaneous:
MISCELLANEOUS: Present with 784 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MQQATGNELLGILDLDNDIDFETAYQMLSSNFDDQMSAHIHENTFSATSPPLLTHELGIIPNVATVQPSHVETIPADNQTHHAPLHTHAHYLNHNPHQPSMGFDQALGLKLSPSSSGLLSTNESNAIEQFLDNLISQDMMSSNASMNSESHLHIRSPKKQHRYTELNQRYPETHPHSNTGELPTNTADVPTEFTTREGPHQPIGNDHYNPPPFSVPEIRIPDSDIPANIEDDPVKVRKWKHVQMEKIRRINTKEAFERLIKSVRTPPKENGKRIPKHILLTCVMNDIKSIRSANEALQHILDDS
The following text describes a protein:
Function:
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Sequence:
MQTTAKSSTPSITAVVAATAENGIGLNGGLPWRLPGEMKYFARVTTGETPSSDPSEQNVVIMGRKTWESIPSRFRPLKNRRNVVISGKGVDLGTAENSTVYTDIPSALSALRSTTESGHSPRIFLIGGATLYTSSLLPSSVPSLNSSTSTSPLPFSRPLIDRILLTRILSPFECDAYLEDFAAHTKPDGSKVWKKASIKEFREWIGWDIEEQVEEKGVKYIFEMWVLNQ
The following text describes a protein:
Function:
Atypical and probable non DNA-binding bHLH transcription factor that acts as a transcriptional repressor that negatively regulates cell and organ elongation in response to gibberellin (GA) and brassinosteroid (BR) signaling. Is able to form heterodimer with BHLH49, thus inhibiting DNA binding of BHLH49, which is a transcriptional activator that regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. Binds and inhibits HBI1, a positive regulator of cell elongation that directly binds to the promoters and activated the two expansin genes EXPA1 and EXPA8, encoding cell wall loosening enzymes. The ability of IBH1 to inhibit BHLH49 and HBI1 is counteracted by binding to the antagonist bHLH transcription factor PRE1, restoring the transcriptional activity of BHLH49 and HBI1 and resulting in induction of cell elongation. Functions redundantly with IBL1/BHLH159 in a regulation node known as the incoherent feed-forward loop (FFL).
Miscellaneous:
MISCELLANEOUS: Plants over-expressing IBH1 are dwarf with round-shaped, dark-green leaves, short petioles, siliques and roots, and are insensitive to brassinosteroid. Plants silencing IBH1 exhibit increased length of hypocotyls and leaves.
Subcellular Localization:
Nucleus.
Sequence:
MASADKLINTDVPEKDVFAFHFLQSLSNLRKQNPFDTPDQKNYRVRKIKKAAYVSMARAAGGSSRLWSRALLRRADKDDNKIVRFSRRKWKISSKRRRSNQRAPVVEEAAERLRNLVPGGGGMETSKLMEETAHYIKCLSMQVKVMQCLVDGLSPK
The following text describes a protein:
Function:
Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Late endosome membrane. Membrane; Multi-pass membrane protein.
Sequence:
MACCGGCDCKCNEYLTYQVVKYLLIIASIFFWLVSAAIMGLGIFAEVVRRDLGSMNTFLVSPAAALIAAGLVVFVVTFLGMAGALRDNLILLKIFIGLMITGLLLQLIVGLVAFAFKDQAKNFINEQVSKGVKSYFADLDFKNTMDWVQERFYCCGGADYEDWEKNDYFRCASPGPASCGVPHTCCDRRANPTAGGVVNTQCGYGVRVYERLELVDIVYIRGCTDAVLIWFEDNFDIFAGLCIGLLLPQILGIVFAGVHIRNVTNIVEEERNKRRYFDRTDGSAYGFQPLPPEAESTL
The following text describes a protein:
Function:
Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.
Subcellular Localization:
Cell membrane. Cytoplasmic vesicle, secretory vesicle, Cortical granule.
Sequence:
MSMGGLWPWVLGLLSVPGLILGAPSASSCPGACEPSFSEGLAPEATQTSWDKDIPAINQGLIPEETPESSFLLEGDILRPSPFRLLSASSNKWPKNDGVVEVPFLLSSKYDQPSREVILEAFAEFERFTCIRFVAYQGQRDFISIIPMSGCFSGVGRSGGMQVVSLAPTCLQRGRGIVLHELMHVLGFWHEHARADRDRYIRVNWNEILPGFEINFIKSPNSNMLVPYDYSSVMHYGRLAFSRRGLPTITPLWAPSVHIGQRWNLSTSDITRVLRLYDCSPSGPDPRGRGFQAHSSGRSPTPASRPHLQRFLKALLAESSGSRAGGQRVAAGPGESLHGLEPPALRNFGVEASARPPQTPASSPRSRPGAGAPGIAPERSWQGQVPTVPPAPSLEAEDQPAPIQAALGKPSSARSQSTWKSHQGDPQRSSLWLLSLSGEGILCPEEPASTTLDPSGQQPCVLAPI
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MAAALCYSNRMGISSKLKLIATRYPVSLVKDRSVYCVGCPTLVCQQMRYYSSSGRRGFLGGLLDNIKQELSKNKEMKENIKKFREEAKKLEESDALQQARRKFKTIELETMKTSEVFKKKFEQMSDTVKESLDEVGKTDLGRKFRESVEEAAKTAKQSAESVTKGGEKIGKTAAFKAISQGVETVKKEFDESVLGQTGPYRPPSRLRKRSEFSGDRTKEEKIFEANEEAMGMVLHKDSKWYQQWKDFKDNNMVFNRFFEMKMKYDESDNAFVRASRTITDKVSDLIGGLFSKTEMSEVLTEILKVDPNFDKDKFLKLCERDIIPNILEAMIRGDLDVLKDWCYEATYSQLAHPIQQAKAMGLQFNSKILDIDNIDLAMGKMMEQGPVLIITFQAQLVMVITNQKGDVVEGDRDKVLRMLYVWALCRDQDELNPYAAWRLLDISSSASEQIL
The following text describes a protein:
Function:
Transcriptional transactivator. May interact with and recruit specific components of the general transcription machinery to viral promoters and stabilize their formation for transcription initiation. Negatively regulates its own transcription. This immediate early (EI) protein may be necessary in virion for viral pathogenesis.
Miscellaneous:
MISCELLANEOUS: Encoded both by ORF62 and ORF71 within the inverted repeat sequences bounding the Us region of the VZV genome.
Subcellular Localization:
Host nucleus. Host cytoplasm. Virion tegument. Note=Localizes to the cytoplasm when phosphorylated.
Sequence:
MDTPPMQRSTPQRAGSPDTLELMDLLDAAAAAAEHRARVVTSSQPDDLLFGENGVMVGREHEIVSIPSVSGLQPEPRTEDVGEELTQDDYVCEDGQDLMGSPVIPLAEVFHTRFSEAGAREPTGADRSLETVSLGTKLARSPKPPMNDGETGRGTTPPFPQAFSPVSPASPVGDAAGNDQREDQRSIPRQTTRGNSPGLPSVVHRDRQTQSISGKKPGDEQAGHAHASGDGVVLQKTQRPAQGKSPKKKTLKVKVPLPARKPGGPVPGPVEQLYHVLSDSVPAKGAKADLPFETDDTRPRKHDARGITPRVPGRSSGGKPRAFLALPGRSHAPDPIEDDSPVEKKPKSREFVSSSSSSSSWGSSSEDEDDEPRRVSVGSETTGSRSGREHAPSPSNSDDSDSNDGGSTKQNIQPGYRSISGPDPRIRKTKRLAGEPGRQRQKSFSLPRSRTPIIPPVSGPLMMPDGSPWPGSAPLPSNRVRFGPSGETREGHWEDEAVRAARARYEASTEPVPLYVPELGDPARQYRALINLIYCPDRDPIAWLQNPKLTGVNSALNQFYQKLLPPGRAGTAVTGSVASPVPHVGEAMATGEALWALPHAAAAVAMSRRYDRAQKHFILQSLRRAFASMAYPEATGSSPAARISRGHPSPTTPATQAPDPQPSAAARSLSVCPPDDRLRTPRKRKSQPVESRSLLDKIRETPVADARVADDHVVSKAKRRVSEPVTITSGPVVDPPAVITMPLDGPAPNGGFRRIPRGALHTPVPSDQARKAYCTPETIARLVDDPLFPTAWRPALSFDPGALAEIAARRPGGGDRRFGPPSGVEALRRRCAWMRQIPDPEDVRLLIIYDPLPGEDINGPLESTLATDPGPSWSPSRGGLSVVLAALSNRLCLPSTHAWAGNWTGPPDVSALNARGVLLLSTRDLAFAGAVEYLGSRLASARRRLLVLDAVALERWPRDGPALSQYHVYVRAPARPDAQAVVRWPDSAVTEGLARAVFASSRTFGPASFARIETAFANLYPGEQPLCLCRGGNVAYTVCTRAGPKTRVPLSPREYRQYVLPGFDGCKDLARQSRGLGLGAADFVDEAAHSHRAANRWGLGAALRPVFLPEGRRPGAAGPEAGDVPTWARVFCRHALLEPDPAAEPLVLPPVAGRSVALYASADEARNALPPIPRVMWPPGFGAAETVLEGSDGTRFVFGHHGGSERPSETQAGRQRRTADDREHALELDDWEVGCEDAWDSEEGGGDDGDAPGSSFGVSIVSVAPGVLRDRRVGLRPAVKVELLSSSSSSEDEDDVWGGRGGRSPPQSRG
The following text describes a protein:
Function:
Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center.
Sequence:
MAVDTNLASLFEKLKLEDLYVPPRPWESIPSECGGISSSNSANTNRSSHVQYSTSAVSESSLVRLTLDALQGVESVLISIQKLSALFCFDSADRSFHHIPSLLTRTSSTLALGNLLKSIGRFGCIIFLLHKFVDHFTCLTPDGNSDEDEVQKYDANDGVGRRMSNHTLVNQAFAISVAKILDGYTSALNTLYASVNFRRCLKSKGGGCFTSVGHGEITLLEAYLHSAGLRTQLDVLGNICNMSDLALRYSELSLEEISAKAFLEFNNFPRSGALLTFLYTQLKMADPAHCALLKFLFLRSWEPYCGFIRAWIFEGRIADPFKEFIVEIVKEQPDHEPGNTGISNDFPLASVRVRQGVLPLFLEDCLLPLFRAGQQLQIITKLLEFCDTFGPFNGIHEELLPGIDGFSSEFPSFRSSLLFEKGTIETMVVSRNSYYQRMLEKVDNVFTKMEFRFREVIFQRPLFQYHLSYISFAFLYSCRICDFFFLSRITRCVESWLIACAGLSIRNYDFCMIVYPVKESLI
The following text describes a protein:
Function:
Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites. Targets mRNAs to regulate their expression.
Subcellular Localization:
Secreted.
Sequence:
MHSKDDKETERCDMGETGSRGDQMTEKEEQRSRRHERDGMRGKMESCVSRCNEKFTRGAACQCDRQCARHGDCCEDYEELCTAEEDPKEPEPFLELEGETEEVPATNLYSAPDSCRGRCLEAFDKHHQCHCNARCRDFGNCCEDFESLCDHEGFSHSSDAITKEELQSISEKIYRADTNKARKEDIIINSQNCISPSETRDQVDHCPEPLFSYVNEELFSKPTYAAFINLLNNYQRATGRGEHFSAQQLAEQDAFLREVTKTAVMKELYSFLRDQNRYSSEQEFVNDLKNMWFGLYSRGNDKGDSSGFEHVFSGEVKKGKVTGFHNWIRFYMQEKEGLVDYYSHIYDGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKMCQLSLGGYPLAIQTYTWDKSTYGNGKKYIATAYVVSSTQ
The following text describes a protein:
Function:
Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation.
Subcellular Localization:
Mitochondrion.
Sequence:
MARRKVRPRLIAELARRVRALREQRERPRDSVRYALDYETLIRPHSGRKLPLRAWVDVRRESRLLQLLGRLPFFGLGRLVTRKSWLWQHDEPCYWRLTRVRPDYTAQNLDHGKAWGILTFKGKTESEAREIEQVMHHDWRLVPKHEEAAFTSFTPAPEETPRPVPYPPLLRAMILAERQKNGDPSTEEPMLSLERIRTDPWDYPENQEAKKKTKGTAV
The following text describes a protein:
Function:
This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. Also, involved in the degradation of oxidized and glycated proteins.
Sequence:
MKKAGILLLSLLMPFSTAFAEASKPLSVELLWQLKRIGSPVVSSTGEHIIAPVTEYDLKEDKGSTQLWRFDVEGKNNRAITAKGLKVSEPVFSPDGKTLAFISERNDDDAGQIYLLPMDGPGEAAKLTDIPTGVNGIKWVGKHLYFISNIFPEQNWEQMKAQLKTDKDNKVSARQWNALPYSQFDHWLDERRQAHVFRIPATGGTVEAVTQPLGHELPRSSQSSESYDISPDERLIAFSAYGSDNRVDPKLDLFLATIGGNKAENITPENPAPDLNPSFSPNGKTLAFTRQKIPGFYADTARLMLLDVSSRKLTTLTPDWDRSVSEFEWTPDSKGFYASIEDAATNRIYHIDAKSGKAKAITQATDFSQPAIAKDGQLIATNQSFLYPARLVSINPRNGKTERLEQFNDDILKDVDLGTYESVTYKGYQGQDIQMWVHYPPGFDRSKKYPLFMLIHGGPHNAISDGFHYRWNAQTFASWGYVTAWPNFHGSSGFGQDFADAINPDWKNKSLEDVLKATDWFKQQSWIDSDRMVAGGASYGGYLTSIILGQPHPFKALLIHAAVYDMYAQMSADFAVHSTRFGNYWDNPELYKAISPHYFAANFNTPTLVSHGQLDYRVPVGQGFELFRTLQTRNVESRMIYFPDENHWIVKPNNSIYWYNQVKDWMAHYAKPGAQ
The following text describes a protein:
Function:
DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAPIPAQSDEYSLLHIERISQYVCLSPASLNSPLPALCASIFSPLLLSYFPPAKGIVLAYEDVQLSSTPPGSKTNSSAAEPLLLRHVDEYTSPFLWATASLLVLRPEANKYLTGRITHQSKTHITLSHLNTFPVSVTKDHLPDTWTWQQAQSGKVSKGWDGRLNDEGGCWVDVNGEKIEGELKIRIRDFDGRMDGRGKGKGFLKVEGSLLSQEEERERREKGQKGKERANGAVRSSGEPIEVE
The following text describes a protein:
Function:
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MKAVAFPAKIANLSFPSNCCSLFFRSPATFLSPALPCRKLTKGIRGLEGLMSQCLSSSSQSLSFSSNSFSSQPESELLQALPSSKPKSPPLQLPWLIVGLGNPGKKYQGTRHNVGFEMVDALADAEGISMNTVNFKALFGKGVIGNIPIMLAKPQTFMNLSGESVGQIVSFYKIPLKQVLVVYDDLDLPFGKLRLLPKGGHGGHNGMRSIIDRLKGSRDFPRLRIGIGRPPGKMDTANFVLRQFNRQEQEELDHTFQTGLEAIRILLLEGFNKSATFVNTRKSMEQLS
The following text describes a protein:
Function:
Histone H5 performs the same function as H1, being necessary for the condensation of nucleosome chains into higher order structures, and replaces histone H1 in certain cells.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MTESLVLSPAPAKPKRVKASRRSASHPTYSEMIAAAIRAEKSRGGSSRQSIQKYIKSHYKVGHNADLQIKLSIRRLLAAGVLKQTKGVGASGSFRLAKSDKAKRSPGKKKKAVRRSTSPKKAARPRKARSPAKKPKATARKARKKSRASPKKAKKPKTVKAKSRKASKAKKVKRSKPRAKSGARKSPKKK
The following text describes a protein:
Function:
Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase.
Subcellular Localization:
Cytoplasm. Note=Colocalizes with tubulin gamma during interphase. During mitosis, enriched at the spindle poles and the midbody during telophase.
Domain:
The C-terminus is required for CDK2-activation, but not CDK2-binding.
Sequence:
MSDSQDPTTSPVVTTQVELGGCSRQGGGNGFLRFRQHQEVQAFLSLLEDSFVQEFLSKDPCFQISDKYLLAMVLVYFQRAHLKLSEYTHSSLFLALYLANDMEEDLEGPKCEIFPWALGKDWCLRVGKFLHQRDKLWARMGFRAVVSRQCCEEVMAKEPFHWAWTRDRRPHHGGVQRVCPQVPVRLPRGPGLSPPHCSPCGLPQHCSSHLLKPVSSKCPSLTSECHRPPSQNYLSRVKNAWGGDFLIVLPPQMQLEPGTYSLRIFPKPPARPGH
The following text describes a protein:
Function:
Involved in pre-mRNA splicing and cell cycle control.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAPPLYVKGGVWTNVEDEILKAAIQKYGIYQWERISSLLPKKSAKQVKARWVEYLSPLLNKTDWTKEEDEKLLNLHKIFPNQWRSISNILNRTAVQCVERYQKLIDEAAGIKPGDDEENLGLSGPGIETLPAVGASSGLAVGEMNLNPESKPARPDDEDLPDDEREMLAEAKARLGNIQGKKAKRKARERMLEESKRIALLQKRRELKSAGINVKLTTRNKKKRKEFDYNADIPHEIIPQAGPYDTAEELKQNDFEKQQFGQQVSTKGISMKDIDDRIAKEESRRKKEIEKKKLERKREFNAAASLISEHEDSKRRKLNLPEPGTHNFEKTKSDVLTLTNQANNKLSEKEIARNQNKKRAAVAQLIKATFERLPPPKHETGEILPFVSTNILEFRNDVNANDISDIAGAKLPDETATNVSTLISRVVQRELPIPHPNNLRDLSTVKFDTLVDKLIAEECHRLIRSDYKQYHDTTINGVSTDKYDRDLLEKINQDIDKEFAQMDVSTVHSFEDYVLPKNFKVAESIIENLHTFHNENEKLTNKILESTNYEDQRDQKLQQLTHLWRELSDVNLSYSIEKKLFELESSAIDKELLRLRSEIDKLNKKIETLR
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MHSVSCFLKEHEGVANGPLSAAVPLWNGLRSDQPPQLAYDQSKLANGHLFAARERSENRLGNGIISTHFTLFSGDCKSNENGDKAPLMQTVSSVVEAPTMDFRGHFELGFGQQMICGKYPYAEQCYGVYSTYGSTQIAGRMMLPFSMASDGGPIFVNPKQYSGIIRRRKKRAKAELQNRLLKLRKPYLHHSRHLHAMRRPRGNGGRFLNTKNSGDTTKKSAGEKQLRQQNFGGSNESSSRSTSPGSEVTTSNDHGGYLFSTAVASAATTTTTINTDVQYPFQMNHVHRSFHQFTDRAVNTAPLGIAMAGSGVLNNMFNTSP
The following text describes a protein:
Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
PAPNAGPSGSWVRSLAVGGGPPGLGPLPRGSCQARGVLRRAAPQPAQRLRRETWAAPLGHQPPRPSPRRRAVCAPRPGAGSVGPRALASRTRPGSVRQRRGAAVKRRGRWEPGPERRGPERRLHTARGGRAGGAPAPCLPPACAPPAPAPRAGPRAGPRARRAGNILTVLQEQRRGLYSRCHCAPLPSRPSNGVEEESLRPLKREPCPNSRGINQHDGLGYPAHFHRGCEQALHQHREDFVCNTLQPGCKNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRRETARKFRRGEKRNEFKDLEDIKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFISRPTEKTVFTVFMISASVICMLLNVAELCYLLLKVCFRRSKRGQTQRNHPNHALKESKQNEMNELISDSGQNATTGFPS
The following text describes a protein:
Function:
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Subcellular Localization:
Nucleus.
Sequence:
MAAQIPIVAATSTPTVARNSKKRPASPSHNSSGGGYGASKKKKLSASGFAQGVSIEAMSESKMASSELSSGPVEKAAKPLPFKDPNFVHSGHGGAVAGKKNRTWKNLKQILAAERALPWQLNDPNYFSIDAPPSFKPAKKYSDVSGLLANYTDPQSKLRFSTVEEFSYIRRLPSDVVTGYLTLRKATSIVP
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MAPIKGLLSLQRTALAQRSSERWGLYGRLFSTQAASTASTPQPTPPPPPPERTHFGGLKDEDRIFTNLYGLHDPYLKGAMKRGDWYRTKDLVIKGSDWIVNEMKKSGLRGRGGAGFPSGLKWSFMPKTTDGRPSYLVVNADESEPGTCKDREIMRHDPHKLLEGCLIAGVGMRAKAAYIYIRGEYVNERKSLQKARQEAYEAGLLGKNACGSGYDFDVYIHFGAGAYICGEETALLESLEGKQGKPRLKPPFPANAGLYGCPTTVTNVETVAVSPTILRRGPEWFASFGRKNNAGTKLFCISGHVNKPCTVEEEMSISLKELIERHCGGVRGGWDNLLAVIPGGSSVPLLPKNICEDVLMDFDALKAVQSGLGTAAVIVMDKSTDVVDAIARLSYFYKHESCGQCTPCREGTGWLWMIMERMKVGNAKLEEIDMLQEVTKQIEGHTICALGDAAAWPVQGLIRHFRPELERRIREHAERELQQAAAA
The following text describes a protein:
Function:
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Domain:
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding; The box 1 motif is required for JAK interaction and/or activation.
Sequence:
MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFTNQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV
The following text describes a protein:
Function:
RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues.
Subcellular Localization:
Cytoplasm. Mitochondrion.
Sequence:
MAAPMVRCGMLLARRLDASRLCLAGKRCLLSAAYVDSHQWEAREKEEYHLADLASLMDKAYERKLPVSSLSISRFVDNIASREDLDSAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKYGAQDKALYTLVNKVQYGIFPDNFTFNLLMDYFIKKGNYKDALSVVFEIMMQEAFDVPSTQFLSLYVLYRCLAEKTELTWEEERDFGASLLLSGLKQRNTVGLSSQLYGYALLGKVELQRGVRAVYHGMPLMWTPGYLDRALQVMERVASSPEDLKLGREVLDVLDGVLKVVTSPDVQTSEAQPQEGEDGLGSANLVEQLDTEEPEQSKLPRYLERFQASRSKLQELNRVESESLLTLTTQLVKEKLPACEAEDLATYEQKLREWHLERVQLIQREQEQREKAKQEYQALSAAEKAA
The following text describes a protein:
Function:
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
Sequence:
MEEKISQAIDDPNVFCFQELWIECQEVQKSQPIDSAVLRTLEIFCRGDIRDASSEWNELRFKKLRLLTLIDLANRHVGSSVSFETILVHLQLDRLPPSDPTFTVEYYIMQAMMNQILVGKINAKTQTLHVSWALERFLDSKRIDEMKYSLDRFIERCSNILFQLDAGTPSVSKSFKRASRMSSSDGIDYMVFDKRPRPDDTDFDL