lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSILTYLEFHLYYTLPVLAALCWLLKPFHSQQDNLKYKFLMLMAASTASIWDNYIVYHRAWWYCPTCVVAVIGYVPLEEYMFFIIMTLMTVAFSNFVMRWHLHTFFIRPNTSWKQTLLVRLVPVSALLAITYHAWHLTLPNKPSFYGSCILWYACPVLAILWLGAGEYILRRPVAVLLSIVIPSVYLCWADIVAISAGTWHISLRTSTGKMVVPDLPVEECLFFTLINTVLVFATCAIDRAQAILHLYKSSVQNQNPKQAISLFQHVKELAWAFCLPDQMLNNELFDDLTISWDILRKASKSFYTASAVFPSYVRQDLGVLYAFCRATDDLCDDESKSVQERRDQLDLTRQFVRDLFSQKTSAPIVIDWELYQNQLPASCISAFRAFTRLRHVLEVDPVEELLDGYKWDLERRPILDEQDLEAYSACVASSVGEMCTRVILAQDQKENDAWIIDRAREMGLVLQYVNIARDIVTDSETLGRCYLPQQWLRKEETEQIQQGNARSLGDQRLLGLSLKLVGKADAIMVRAKKGIDKLPANCQGGVRAACQVYAAIGSVLKQQKTTYPTRAHLKGSERAKIALLSVYNLYQSEDKPVALRQARKIKSFFVD
The following text describes a protein:
Function:
RNA helicase.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MDAFDLFRKLGSGAKFDLKRFAKDAERFKVGKSQSKDSSDQLSGIRYFGRETQEDTSLDSRPNEDDAEEGEASDEEQKQATESVKAARKKKKGAKRKSEDAEPETREGEGIQWMSLQNKTKEAKQESKDKPSLKRLKQLHNEKVNRIRHQNRINVHGTDIPDPVTTFEELQKEYDLDPRIIHNIQAAGFHTPTPIQMQAVPLMMHKREILACAPTGSGKTMAFCLPLLAHLRQPLNKGFRALIISPTRELATQTHRELLKLSEGVGFRVHMINKGVEAVKKYGPKSAKKFDILVTTPNRLIYLLNQDTPAINLSSVEWLVVDESDKLFEDGKTGFREQLATIFLACSSPNVRRVLFSATFATDVERWCKLNLDNLVSVSIGARNSAAETVEQQLLFVGSENGKILAMRNLIKQGFLPPVLVFVQSIDRARELYHELVYEGINVDVIHADRTQQQRDNVVSSFRSGKIWVLICTALLARGIDFKGINLVINYDFPTSAVEYIHRIGRTGRAGHKGKAVTFFTEDDKPLLRSIATVIKKAGCPVPDYMIGFKKIKSKLKHQLVTKPPRRAAIRTTPRMLFDRKLGKGKRKKRKATAKEAKGEAPEVISNC
The following text describes a protein:
Function:
Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X-X-S/T-C2 of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates microneme protein MIC2 and may play a role in its stabilization. Probably by regulating protein O-fucosylation, may play a role in tachyzoite adhesion to and/or invasion of host cells; however, POFUT2 involvement in adhesion/invasion is controversial.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MHCQLGGQARALIFLMFESCRNSWHVSPWSSVPFLPSPCLFFSFSALPFLHPLSQLIACRGSSATWLFPVSSGTLVLRYALAASPPRGTMRPSTNPRTAEEGRPWLIHATQTGPQTASVLSLFPAVNAGFFSACRQHRGGRPPCLLNHRRLLLGLVSVLTVFLSCLPFTNATVSPAALQDVCYAFGNISRKLSSFLVPSRVTCPRGATPLSGVEAQDSLEHPEIPDFRFLVYDVKNGEGFHLQKEVIYRVALVISLLNARSAQQGRMTDVHTAEKAREDRGHPQASHMLCASSSFSHACSARSTFPFFPMWVLVLPPWCRLAHWHFSEETITAMAENSWLKHVRWGTFFDFQDLGERLPVMEYEDFLTYQLMRPDPWGERRQRKEKQTTPVELDVVLSVRFSSTPSSRSLPFCACLSSRASEIADEQAQRDDVCCNVNDLPGCPQIHAALTPQERQRAPAQRGGDPREEIDEQTGEFNEGHNPSGDGEREKRKPGRRSDTSRSRKEIQEEAKVSDTWSGVSLWLAGFCETVRALEMWCASLYIADAPRIADLLWRSVAERPPGAIQTVWLKFGENLLVPWPDVLLDAHLLDMLHVHPKLRQIGDLFINKFLSNRDKTETGKGERASTEGGTEGDENLAKHGYIAAHLRRTDFLYLKRSVPLQRAAAYLVSRMKEHGVFKAFICTDGSEDEKRELRDAVRRVGDAASSSPYTVVFFDLPTVRRLMIKTLEASSHVSDDGSFHDLKAVETPGYSGPNHISLLLHPGITALIEVWIAARAAYFIGTKDSRFSQAIRWERHLMGHPLDSSLEVFCVDSSPDQTGGQAQGKCFATKSHDPPEGRSRSELRRKYWPSLDPSSTL
The following text describes a protein:
Function:
Involved in chloroplast biogenesis. Required for thylakoid membrane development. Seems to be required for plastid-encoded plastid RNA polymerase (PEP)-dependent gene expression.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAFTFLSPHPVFLSLTGTTSSFSYKPVLLPFSRNSRTLTVAAGPARRNSYPNPADDDPPEAPEDSMHGVSKFQQIQRQAARARKLEEEDFEKNRNTYLSAIADVEDAAETGRDDEESGGDLFSDIDRAISMKRSEFVKQGLLKPNPPKTASLKKIGEEGNEEEGDVTDDVDELDEEEVVDLDEIDKLTGLTEISDEEDWVDEEGNTRINKKKEFGSDHQFEFDLDDFGESKARIVEPKFKMCLAELLDESKVVPISVYGDLDVEITGIQHDSRGVSAGDLFVCCLGSENFLSEADKRGAVAVVASKEIDIEDTLGCRALVIVEDTNAVLAALASSFYRHPSKNMSVIGVTGTDGKTTTTYLIKSLYEAMGVRTGMFSTVSCYIHGDNKLDTPNATMNPDAVLVQSLMAKMLHNGTESLVMEASPQELALGKCDEVDFDIAVFTNLTRENTDFRGTDEEYRDAEAKLFSRMVDPERHRKVVNIDDPNAAFFVQQGNPNVPVVTFAMENTKADVHPLKFELSLFETQVLVNTPQGILEISSGLLGRHNIYNILAAVAVGIAVGAPLEDIVRGVEEVDAVPGRCELIDEEQAFGVIVDHANTPDGLSRLLDSIRELKPRRIITVIGCEGENERGKRPLMTKIATEKSDVTMLTSDNPRNEDPLDILDDMLSGIGWTMQEYLKHGEHDYYPPLANGHRLFLHDIRRVAVRCAVAMGEEGDMVVVAGKGHEAYQLEGEKKEFYDDREECREALQYVDELHQAGIDTSEFPWRLPESH
The following text describes a protein:
Function:
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
Subcellular Localization:
Nucleus.
Sequence:
MSPLLKEYLGRRVVVVTTDGGCLVATLEGFDKTANLLLSDVRQRATGEGLAAAFLLQGSQIVCCGPLEGGGPEQEPQAAALRDTRNVVAREHDIWARAWQARQARE
The following text describes a protein:
Function:
Involved in the anaerobic nitrogen utilization via the assimilation of allantoin. Catalyzes specifically the hydrolysis of allantoate to yield CO2, NH3 and S-ureidoglycine, which is unstable and readily undergoes a second deamination by S-ureidoglycine aminohydrolase AllE to yield S-ureidoglycolate and NH3. In vivo, the spontaneous release of S-ureidoglycolate and ammonia from S-ureidoglycine appears to be too slow to sustain an efficient flux of nitrogen.
Subcellular Localization:
Cytoplasm.
Sequence:
MITHFRQAIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFKKRMAASGLETRFDEVGNLYGRLNGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWLAIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNSFVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPRPNTVNVVPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKELVATLTELCEREKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITDLAEGVKTLALMLYQLAWQK
The following text describes a protein:
Function:
May recognize microbe-derived N-acetylglucosamine (NAG)-containing ligands.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MAVSVSKQYMTSLVVILLFISLSSLSPTSTSHSCDPVEEEEEASSFGYVCHSNLQKCHTFAILRAKPPFYSLSDLSRHLGLDADDEYVPKGQLLLIPIECRCNGSIYEASLIKNCVKGDTFRSVSQSLQGLTTCLSIREKNPHISEDKLGDNIKLRLAIRCSCPQEGVSNASFLVTYPVGVRDSVSSLAVRFNTTEDAIVSANNKSGVVPLKPALIPLDHKPEKQGSRKRNPSKKKRSKMKLMIAVSSAIAGVCGLVTLMVFGYLHWKKETQIQTQTQKWISNKDPETRQLSLSIRTTSDKKISFEGSQDGSILDSHNTVGTTTPRKPVLEIYAFEELEKATENFSSSNHIKGSVYFGSLKGKDLAIKQVNADEMKRFDFGLLNDQSHYYNHNVIRVLGTCFREIDQDSYLVFEYARNGSLWDWIQNKLAIKNQFIESCYCFLAWKQRIKICHDVAIALKYMHRINYVHGNIKSRNIFLNEDLRGKVGNFGMSKCVTNELATEENLIESSLSPASDIFAYGIIVMEVLSGQTPDMLLGLQEVETTSLGTQETFVSEWSRLRRLLGDKEKLREVMDSTLGESYSVDSAFEIASIARDCTAEEAESRPSAVEIAERVSRLVDDDEDEEDEAVIDRESTLISESSYKPLVKKSSIID
The following text describes a protein:
Function:
Forms the cylindrical rigid tail tube with a 4 nm wide central channel for DNA ejection. The tube is composed of 31 hexameric rings.
Subcellular Localization:
Virion. Note=Constitutes the tail tube.
Domain:
The C-terminus probably makes protruding decorations on the whole length of the tail tube.
Sequence:
MKLDYNSREIFFGNEALIVADMTKGSNGKPEFTNHKIVTGLVSVGSMEDQAETNSYPADDVPDHGVKKGATLLQGEMVFIQTDQALKEDMLGQQRTENGLGWSPTGNWKTKCVQYLIKGRKRDKVTGEFVDGYRVVVYPHLTPTAEATKESETDSVDGVDPIQWTLAVQATESDIYSNGGKKVPAIEYEIWGEQAKDFAKKMESGLFIMQPDTVLAGAITLVAPVIPNVTTATKGNNDGTIVVPDTLKDSKGGTVKVTSVIKDAHGKVATNGQLAPGVYIVTFSADGYEDVTAGVSVTDHS
The following text describes a protein:
Function:
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
Sequence:
MSQKKFIVQVEPAVAVKDGTPSMGPVYRSVFAKHGFPAPVDGLESCWDIFRLSVEKYPDNPMLGTREFVNGKHGAYKWLTYKQVYDKVIHVGNAIRSCGVEPEGRCGIYGANCAEWVISMEACNAHGLYCVPLYDTLGADAIEFVICHAEVTIAFADEKKICELLKVIPKAREHLKTIVSFGKVTLVQREQVEKFGLAIHSWDQFLSLGDDKNFNLPLKKKSDICTIMYTSGTTSDPKGVRISNNCMVTLIAGVNHLLDSAQVSLNTNDVYLSFLPLAHIFDRLIEECFFNHGASIGFWRGDVKMLIEDIGELKPTIFCAVPRVLERIYSGLQQKISAGGFIKRNLFNLAYSYKLRNMNAGIEHSKASPLSDKIIFSKVKQGLGGRVRIILSGGAPLAPHVEAYLKVVTCSHVLQGYGLTETCGGSFVSMPNEMDMLGTVGPPIPNLDARLVSVPEMNYDALSSKPQGEVCIRGDVLFAGYHKREDLTKEVLVDGWFHTGDIGEWQPDGSMKIIDRKKNIFKLSQGEYVAVEYLENVYGLVPDIDAVWIYGNSFESCLVGVVNPHKQAIEHYAETHNISGDFDSLCENPKIKEYILGELNRIGKEKKLKSFESVKTVHLDPVPFDLERDLLTPTFKKKRPQMLKYYQVILLLLLLSF
The following text describes a protein:
Function:
Involved in auxin transport. Positive regulator of the auxin signaling pathway involved in gravitropism, plant growth and grain development.
Subcellular Localization:
Cell membrane.
Sequence:
MERWAAPKVTAGSARRYVADQPSFSSTLLDAIYKSMDEQPGHGGGATGVEAVAAAAKKQHEAALHYGYYYKPSLAGSYRARAPGPHATTSSSSECSSYGGFSSSEAESSHHRRLRPIRTTVPGGAPGPAPEKKAKKPGASIRAKLRDLRKPASPGARLAGFLNSIFAGKRAPATPPSATAGAESACSTASSYSRSCLSKTPSTRGQAKRTVRFLDSDTESLASSTVVDRRRVPVEAVQQMLLQRMEMESDEDDDESSDASSDLFELENFAAIAPAGAAYRDELPVYETTRVALNRAIGHGYGHGRSARVV
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MDTPGKGPLQAGTSPSGKQRSNFKGCCIFFVLVAAVILVAAAVLIPTVLIPRLRDKDKPAGHISKALDRIALACNITRFPDTCKSTIVGTTAAESDSIWIPNLAVAAATDAVTSILSRCRAYNLDPEVIFNATYGSIVDDCLEILQYGLQYLTSSSETLSKFPGPEQNREPPINELRTWVSGALTVTGACSDTLSRIQTVKSAPLRQQANQTFQVVSNALAIVNSFAVYGDDLEKWQPAYFLGNSRGPLSKSARRMLLSTEDSPQFKLRRSNPLSISGGSCESSPNHNSCSSTTGSSLNVAGSLPNWLRSQDRRLLLEESFPIANITVAQDGSGNYTTIQEAVDAAPINSSIRFVIHIKSGVYDEVVRVPFLTKNVMFLGDGINQTIITGNRSVQNPSITTFKSATVGVAGEGFMARGLTILNTAGAVAQQAVALRVSADKSALWQCSLHGFQDTLWAHAFRQFYKDCTISGTVDFVFGNAAAVLQSCTLLARVNLPGKQNVFTAQGRTDPGQWTGFSIQDCTLDGTPDLLQLNSSSQQLTYLGRPWKQYSLTVIMKSYMSAIIDSAGWLPYSGDFAFTTLFYGEYGNTGPGAKTEARVNWSTAITDPAVVTKFQVGQFLHSATWLPSTGIPYTDS
The following text describes a protein:
Function:
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Sequence:
MSCPFHTTTNTSNRSPLPDRALLLAMKSQTNTFILGTRKSNLALVQTGHVADDLRRLHSGAGSKFGETREEGDDAEQGDVPFVHPYTFSIESMTTVGDRNQTTPLHLLSPYSSTQPAKSLWTDELEARLINGHFDMLVHSLKDVPTVLKDGCEIGCMAKRHDPRDALVVKQGLPYKRLEDLPDGAVVGTGSVRRVAQLKRAFPNLVFEDMRGNLNTRFNKLDNPQSPFSALILAMSGLERLGMAHRATSPLSSPTLMHAVGQGALAIEIRSTDPRVRNCLRGLGHWQTEWSCGAERGCLRVLEGGCSVPVGVESELVELDEDEVAAHPELLEGVEDPFKGQEEIPLEGDSPMLWFSGLVDTTSAPTPSTPTFSSHSLPPLRTRLAKLTLHSCVTSTDGSKHVLFTPPPVLVRSYRQAEQFGEECARRLRGMGAGEILDEINKLRKERELRDLESAIERSRAAQEESEKMGLVQDGTAEVVA
The following text describes a protein:
Function:
Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 eIF-2-alpha in response to low amino acid availability. Plays a role as an activator of the general amino acid control pathway required for adapatation to amino acid starvation. Converts phosphorylated eIF-2-alpha either to a competitive inhibitor of translation initiation, leading to a global protein synthesis repression, and thus to a reduced overall utilization of amino acids, or to a translational initiation activation of specific mRNAs, and hence allowing reprogramming of amino acid biosynthetic gene expression to alleviate nutrient depletion. Binds uncharged tRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MGRSSSKKKKKRGGSGRRGQLKDHGSNADEDNELLSEEITALSAIFQEDCKVVSDSRSPPQIAIKLRPYSKDMGYEDTDISAMLIVRCLPGYPYKCPKLQITPEQGLTTADAEKLLSLLEDQANSNAREGRVMIFNLVEAAQEFLSEIIPESHDEESVPCLTAHRSTQFIEQPMLSNIAKSCSGGPFVYGFIDLFSGLEDARNWSLTPDENRGIVSSVQSHPLDTSRILHQKPDKNLKRFEDHAKEEVALPAPIAKLNTVQEENVDDTSISSFDSSKSTDDVESGLFQNEKKESNLQDDTAEDDSTNSESESLGSWSSDSLAQDQVPQISKKDLLMVHLLRVACTSRGPLADALPQITDELHELGILSEEVLDLASKSSPDFNRTFEHAFNQNMASTSVPQFWEPPSDSCEPNASLPSSRYLNDFEELKPLGQGGFGHVVLCKNKLDGRQYAVKKIRLKDKEIPVNSRIVREVATLSRLQHQHVVRYYQAWFETGVVDPFAGANWGSKTAGSSMFSYSGAVSTEIPEQDNNLESTYLYIQMEYCPRTLRQVFESYNHFDKDFAWHLIRQIVEGLAHIHGQGIIHRDFTPNNIFFDARNDIKIGDFGLAKFLKLEQLDQDGGFSTDVAGSGVDSTGQAGTYFYTAPEIEQDWPKIDEKADMYSLGVVFFELWHPFGTAMERHVILTNLKLKGELPLKWVNEFPEQASLLRRLMSPSPSDRPSATELLKHAFPPRMESELLDNILRIMQTSEDSSVYDRVVSVIFDEEVLEMKSHQSSRSRLCADDSYIQYTEINTELRDYVVEITKEVFRQHCAKHLEVIPMRLLSDCPQFSRKTVKLLTNGGDMLELCYELRLPFVHWISVNQKSSFKRYEISHVYRRAIGHSPPNPCLQADFDIVGGTLSLTEAEVLKVIVDITTHIFHRGSCDIHLNHGDLLDAIWSWAGIKAEHRRKVAELLSMMGSLRPQSSERKLKWVFIRRQLLQELKLPEAVVNRLQTVASRFCGDADQALPRLRGALRADRPTRKALDELSNLLTYLRVWRIEEHVHIDVLMPPTESYHRNLFFQVFLTKENSSGTSNDGVLLAVGGRYDWLVQEVCDREHKMNLPGAVGVSLALETIFQHLPMDLRPIRNEVSTSVLVCSRGGGGLLVQRMELVAELWEKSIKAEFVPTPDPSLTEQYEYANEHEIKCLVIITESGVAQNQIEFVKVRHLELKKEKVVGREELVKFLLDAMAVQFRNPSVWS
The following text describes a protein:
Function:
Patulin synthase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. PatE catalyzes the last step of the pathway which is the conversion of E-ascladiol to patulin. The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units. The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol). These first reactions occur in the cytosol. The intermediate m-cresol is then transported into the endoplasmic reticulum where the cytochrome P450 monooxygenase patH converts it to m-hydroxybenzyl alcohol, which is further converted to gentisyl alcohol by the cytochrome P450 monooxygenase patI. The oxidoreductases patJ and patO further convert gentisyl alcohol to isoepoxydon in the vacuole. PatN catalyzes then the transformation of isoepoxydon into phyllostine. The cluster protein patF is responsible for the conversion from phyllostine to neopatulin whereas the alcohol dehydrogenase patD converts neopatulin to E-ascladiol. The steps between isoepoxydon and E-ascladiol occur in the cytosol, and E-ascladiol is probably secreted to the extracellular space by one of the cluster-specific transporters patC or patM. Finally, the secreted patulin synthase patE catalyzes the conversion of E-ascladiol to patulin (Probable).
Subcellular Localization:
Cytoplasm, cell cortex. Vacuole. Secreted. Secreted, cell wall.
Sequence:
MRLTSGIFHAAIAVAAVGAVLPEGPSSSKTHRNEYARRMLGSSFGIPKNQTFDYLVIGGGTAGLTIATRLAEQGVGSVAVIEAGGFYELNNGNLSQIPAQDAFYVGTDLDDWQPGIDWGFHTTPQAGAYDRVSHYARGKCLGGSSARNYMAYQRGTKAAHQRWADTVGDSSYTWEQFLPFFEKSLHFTPANDALRGANASVVSDPSVLGNGDGPLSVTYPHYAQAFATWAKHAFIEIGLQIRSGFQSGALLGQSYGLYTINATTMHRESSETSFLRKGLADPNLTVFQSALAKRIRFQDKRAVGVDVETMGRAYTLSARKEIVLSAGAFQSPQLLMVSGVGPAATLKAHNIPLVADRPGVGQNMQDHIIYAPSYRVNVITQSALLNEEFEAQANRDYNERAAGIYANPTSDILAWEKIPEPKRSAWFSNHTRQVLAEYPDDWPEVEFLTMGGYFGYQRNYIRDNPSDGYNYASLAVSLCTPRSRGNVTITSPDAGVPPVINPNWLTDPVDVELAVAAFKRTRDFFNTTAIKPILIGPEYFPGSQVATDAEILDHVRKSFDTIFHASCTCAMGLANDTQAVVDSKARVIGVEALRVVDASALPFLPPGHPQSTLYALAEKIACEISGNC
The following text describes a protein:
Function:
Lectin involved in innate immunity. Agglutinates all types of human erythrocytes, Gram-positive and Gram-negative bacteria. Has a stronger agglutinating activity towards Gram-negative bacteria than towards Gram-positive bacteria. Specifically recognizes acetyl group-containing substances on agglutinated cells. The hemagglutinating activity was inhibited by EDTA, acetyl group-containing mono- and disaccharides, N-acetyl derivatives of amino acids, other acetyl group-containing substances, propionamide and benzamide. Enhances the antimicrobial activity of big defensin against Gram-positive bacteria but not against Gram-negative bacteria.
Subcellular Localization:
Secreted.
Sequence:
MILNVSLFLIFLLAQNVSLETRTTSEKPLSNPASKNASIRIPPITGKLPQRTPRNCLDVKKSGQSASGIFKLKPREDAESFLAFCDMETKGGGWTYFLNRQDGSQNFNLEWEDYKWGFGNLNGEFWMGLQHLYELTGEGGYELLVELEDWAKVKVYARYGLFALGSENEGYSLKVLGRYSGDAGDSLSFSAGSKFSTKDNDQDYASLHCAEVYKGAWWYKDCMRAQLTGQYKKETVGPNEEYLIMFWQSFRGSRYSLKKVKMMVRPFEKKLN
The following text describes a protein:
Function:
Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
Sequence:
MKEAIVNILKNSSHTFISGQYISDKLGVSRTAIWKYINGLKKEGYNIESASKKGYRLISCPDILTFEEIISLLKTKVIGQNIIHFDSINSTNDKAKKIASSENDGTIIISEEQTLGKGRLGRTWFSSKFKGIYMSIILKPDINTMDVPKITQIAAAAVLTALLNNNIKAYIKWPNDIIVNNKKVCGILTEMSGEINKVNYVVVGMGINVNCEEEDIPKDLLSKATSLKIEKDREFKRNILVADILNNFENLYTELIECNNIDTSIEICKENSILIGKEVRIINRTRESFGKAVGLNSNGELLVQFENGEIKPLISGEISVRGMNGYV
The following text describes a protein:
Function:
Actin-associated protein that may play a role in modulating actin-based shape.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
VMVVEEAVITLSGGAPWGFRLQGGADHRKPLLVAKVRKRSKACRAGLCEGDELLSINEKPCGGLSHAQAMNLIDSCPGVLHIRVKRAPTGFQSVVLVPRAPSPRIDKEYRAALRALSPPQPTGPEVTRARLMSPTLRGPEALPEECAHRDCLTSPPDSEAYYGETDSDADTAHEKQRRQKRRSPSSSPGKASGKASPAETSEAGNSAENSSASTDDQSPRDGQGAVEVDSGFQEPPNPLPPLVSPERARGVSLLLSGSRQLVPMVGPVDNPVDEELTVTYMDKAKQAKLHRSESVQEKQVKEARTKCRTIASLLTDAPNPHSKGVLMFKKRRQRAKKYTLISYGSVEEDQLRADMEGDEDEEDGVLPTSESEFDEDGFAAAADADTTWDSDYLDILEKKDPASQRSSSPGAPESPGLPGSAGRGAQLFEQQRKRAEEHTVTGSVPEVAQMPREAGTPNTQPSTPITPPSYSVMNGDISPKSRSAELMSPPHLAPMPLPDLPSSSVLNRTARPFTPGFVSSRAATAPVIFRPTSARKTPSQPPSSQPMASVPAPFSAPPASAPKLAISTASLYIPARSASAVAPLSVLSPPPPFSPPPAPAAPLPSSLQPPAAAPPVAGPIAPPAYSAPSSTEALVSREQRISVPAARTGILQEARRRSTKKPMFSRPEEKKGSSPNPELLSLVQNLDERPKGVTEAGFESGPEEDFLNLGAEACNFMQAQKHKVPPPVAPKPRIHVPEIPQLGGKGAELFARRQSRMDRFVVDTSPQQTSQPASPARPRLPSPTPSLPSHWKYSSNIRAPPPIGYNPLLSPSCPPGAQRSTKAAEAPKTGTWSGRKTSQKEGIKAIDFIRRQPYQLNPAMFSFGSSGSSVAQQSRPLMGSSLTQPRQIPVKAARVYEIKRFSTPTPMSVPTSLTPTVIAPRAATTLGEPLFRSNICSPPPTTTAPPPASAPAPAGTPVQEAKQYQTTPEVPKPRFQASKIGIQSNVWRPGALRY
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
Subcellular Localization:
Cytoplasm.
Sequence:
MPKKKIQKVTPEEVLAEFPYPEESIEEVEEFLESHELVDNEDLYVDVKEDKLPESVEEEVEIPEEIELDDPVKMYLKEIGKIPLLTPEEEIELAKRVEQGDEDAKKRLIEANLRLVVSVAKRYIGRGLSFLDLIQEGNLGLIKAVEKFDWRKGYKFSTYATWWIRQAITRAIADQARTIRIPVHMVETMNKIHKITRLLTQSLGRKPTEEDIAKFLVIQQKLQEFEVYQESGEKISDDEIVEISMLSLDEIAKKLVELHLKTKGKKELTKEKINEEAKELRHVLEEEIKQQTEKVREISMMGQEPLSLEMPVGEDEDNRLADFVENKDLSPADIAVQKSLKKDIEELLNELSEREREILKLRFGLEDNQPRTLEEVGKLFNVTRERIRQIEAKALRRLRHPSRSKKIKDYLED
The following text describes a protein:
Function:
Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme.
Subcellular Localization:
Cell projection, cilium, photoreceptor outer segment. Cytoplasm, cytoskeleton, cilium axoneme.
Sequence:
MSDIDPRNPSQPPDHFSESGQTMIPRHPQITDPISSKHVCFYKSGDPQFSGLKMVINNRTFKSFDALLDTLSKKVPLPFGVRNITTPRGIHGINHLDELEDGKSYICSDQKKVKPIDLDVASKKPVPWYTTRPVSARRRAVHLARQNDSRIMKRENSLVVRTPKKLVVFKNGDSGIKHTIMLQKKTSQTFESLLGHVTEVMQFPVVKLYTPDGRRVDSLQSLILCSGVVVASGREPFKPGSYDPQTQTLPAKLPGVSSHVQPKHRERLGRRNRKKKSVSSTRSRNFSLSSENLYDMPIPSNTMESAETCTCVEGDIPVMPHDEDIEKSFRVNQDGSMTVEMKVRLTIKQEETIQWTTTLSRSSVSNQINVACISHPEPGGSSSNPNLVAATELTCAAEYTSKEKGTNQSSQEGRDEKVPAFRETQEYDFWQDLALNKHDTESKDKVCFRRPPTPGPRRTKKKQTSLESLKTVLEKEIEENVVGTYAYIEETENGDVKKEYCMVSQCSSRPIPKPRKTGSVEINNNDVHSSVKSSGVANILKLHDNGEEITETVLHIVEHQSCHDNFFANLKCGLEGKFTCGRPASSDITLCSLGNEYEVHYKRPSTASESLNGRKNGNTSFSSDLMINSYTSRNNLSSVRNDETGFSVNLLSKALPPKTECSEFSSGGYTKDQVSPSIQGKKNKQAKPKVKKINVPTNVSSYSKGREKKDMTSQKDTRKAISDILTSGEKQIKHTEESPSNFQQVNKIKKSNKKKKGMEEENINSFSVLSLSENAYALNIENTKGLMAEKELNYSEVKSIKDNQMVCLNGSEEHTCFKKIVLPPIDSSGQDKMRQKKQKKTEQNSSEKETRELSENASLLELYSSPSLVNEKVENWLENLQSGSRSCQGNVSHNEADTDNKVIFQIGSDPSEESEVTGETKENHTEYLHAGKINTIKRQIESVSKMEKLEEASDEDSNKKQSLHDSIPNTETNPIALTQQRKTQKTTEAAIQTEFGEICGNSPSQPDLKPVLEQLCCSVKSIQKQQTSNSKRFSSLEKSSSLPDLSSNVASTLGASSKVILAFLSVLALREGITDMDNTVLLTKNRSSTEALKLMESLKKMASIETEGELMIGLSDSQQTTSSHLLLPCSDHQEITGKGNNHDFLAAFSETNTLLEAYTDENHKNMDHTFDIQDSIAEPGIPEELQTVELAPVDKQSKEVNIKEEQNHKSEEIHCYDESIHQDETSLNGELSSNEPSCLLTEEIPHREEFTAFKEASYVEEQLCSANDELQMSQSGGIKEAKHISFEQKADEEFMGENLDGCLTNDNGYAKEHSSSVSIPKDILNDERKKPGIAESVKSVDDMVESSSKDSLCSSLAFSYDSKIAMKKETGGVNIKSIKEMFMAKSTQDLQFGKKRLPSPSTSDLSDYRPETSDSSGSGYRSQASCELTTESGEDISGRQSISKGYVRKTIERLYGTNEAKVLSVTRPPAAPKQKRKVSPGENSTGCISSPVDTKPKATSDLLYFNAKSSLDLNNKSKQSSPHTALSDPNDGVLIDKGRWLLKENHLIRKSPPEKLGMYGNIETTSAETGLDNTSEDAPYSYFGSHHPPLAVISSSELEELAKPGEPKCTYFNMPHASDSEPFPDDILDPSGEPAKMWAEKNGSLPSFASVEFRLPDNKVHPEQGPSVAHPVISQPARAGSTNGRSPEEQDSLEKLHIMCGQHCPILTVKVEPLHEENRGYVYQKPSDLEN
The following text describes a protein:
Function:
Transcriptional activator of alpha-amylase expression that binds to 5'-CAACTGTC-3' motif in target gene promoter. Positive regulator of abscisic acid (ABA) responses leading to growth arrest during seed germination. In vegetative tissues, inhibits growth by reducing cell proliferation. Promotes the expression of aleurone-related genes (e.g. CP1, CP, GASA1, BXL1 and BXL2) in seeds. Together with MYB65 and MYB101, promotes the programmed cell death (PCD) the vacuolation of protein storage vacuoles (PSVs) in the aleurone layers during seed germination. Binds to a GARE site (GA-response element) in the LEAFY promoter, essential for its gibberellic acid (GA)-mediated induction. Together with MYB65, facilitates anther and tapetum development.
Subcellular Localization:
Nucleus.
Sequence:
MSYTSTDSDHNESPAADDNGSDCRSRWDGHALKKGPWSSAEDDILIDYVNKHGEGNWNAVQKHTSLFRCGKSCRLRWANHLRPNLKKGAFSQEEEQLIVELHAKMGNRWARMAAHLPGRTDNEIKNYWNTRIKRRQRAGLPLYPPEMHVEALEWSQEYAKSRVMGEDRRHQDFLQLGSCESNVFFDTLNFTDMVPGTFDLADMTAYKNMGNCASSPRYENFMTPTIPSSKRLWESELLYPGCSSTIKQEFSSPEQFRNTSPQTISKTCSFSVPCDVEHPLYGNRHSPVMIPDSHTPTDGIVPYSKPLYGAVKLELPSFQYSETTFDQWKKSSSPPHSDLLDPFDTYIQSPPPPTGGEESDLYSNFDTGLLDMLLLEAKIRNNSTKNNLYRSCASTIPSADLGQVTVSQTKSEEFDNSLKSFLVHSEMSTQNADETPPRQREKKRKPLLDITRPDVLLASSWLDHGLGIVKETGSMSDALAVLLGDDIGNDYMNMSVGASSGVGSCSWSNMPPVCQMTELP
The following text describes a protein:
Function:
Flavoenzyme involved in polyamine back-conversion. Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and its acetyl derivatives. Substrate preference is spermine > N(1)-acetylspermine > thermospermine > norspermine. Plays an important role in the regulation of polyamine intracellular concentration. Involved in xylem differentiation by controlling thermospermine homeostasis, and participating in the tightly controlled interplay between auxin and cytokinin that is necessary for proper xylem differentiation. Involved in the production of hydrogen peroxide in response to salt and cold stresses.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKKARIVIIGAGMAGLTAANKLYTSSNNTFELSVVEGGSRIGGRINTSEFSSEKIEMGATWIHGIGGSPVYRIAKETGSLVSDEPWECMDSTIDKAKTFAEGGFEIEPSIVESISGLFTALMELAQGKEISQSDADLSRLAHIYETATRVCSKGSSTSVGSFLKSGFDAYWDSISNGGEEGVKGYGKWSRKSLEEAIFTMFSNTQRTYTSADELSTLDFAAESEYQMFPGEEITIAKGYLSVIHHLASVLPQGVIQLNRKVTKIEWQSNEVKLHFSDGSVVFADHVIVTVSLGVLKAGIETDAELFSPPLPDFKSDAIRRLGYGVVNKLFVEMSQRKFPSLQLVFDREDSEFRFVKIPWWMRRTATITPIHSNSKVLLSWFAGKEALELEKLTDEEIKDAVMTTISCLTGKEVKNDTAKPLTNGSLNDDDEAMKITKVLKSKWGSDPLFRGSYSYVAVGSSGDDLDAMAEPLPKINKKVGQVNGHDQAKVHELQVMFAGEATHRTHYSTTHGAYYSGLREANRLLKHYKCNF
The following text describes a protein:
Function:
Required for normal Golgi function.
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MRMSSASAGEYRPSAVSLSSNGGGQRDAESLFRTKPMSEIRIVESATRKNIEDKKEELRQLVGTRYRDLIDSADSIVHMKSLCESISANISSIHGNIRSLSSSSVAETPKLASLNPVRVNVYGIACRVKYLVDTPENIWGCLDESMFLEAAGRYMRAQHVQQRLIKLEGCGGGVAEVDQSKLLANFPLLEHQWQIVESFKAQISQRSHERLLDPGLGLGAYVDALTAVAVVDELDPEQVLELFLDSRKTWILQKLNACTGEDAGEVVLVFCDVLSVIQVTVGQVGELFLQALTDMPLFYKTILSTPPASQLFGGIPNPEEEVELWKSFRDKLESVMLILDKNDVSKSCLTWLRECGGQIVGKVSGKHLIEAIVTGAELGSAEKLIRETMDSKDVLRGSLDWLKSVFGSEVELPWNRIRELVLGDDLNLWDEIFEKAFVERMKSIIDSKFENLTKAVNVADSVHAYSEITGEKINFQAYLNRPSTGGGVWFIEPNSKKVGLISGNKSSPEESDFQSCLTAYFGPEVSQMRDAVDRRCHSVLEDLLSFFESEKAGPRLKDLAPYVQNKCYDSVSALLADVDKELEFLCAAVKKENKDSEAIPPAIIIEKSLFMGRLLFALLNHSKHVPLILGSPRLWCRETMTAVSDKLSSLLRQPRFSSNTPATADSPGKQLHTDLRKQTSLAVAALLGAEEKTSPKFEELNRTMRDLCIKAHTLWIKWLSDELSAILLRDLRSDDGLSATTPLRGWEETIVKQEQDESQSELKISLPSLPSLYMISFLCRASEEIHRIGGHVLDRSILQKFASSLLEKITIIYEDFLSAREASEPQISEKGVLQILLDLRFAADVLSGGDTSTNVETPKSTINRSAYRRRQDQQKTKLVNRGRIDGVTSQLTQKLDPIDWLTYEPYLWENEKQSYLRHAVLFGFFVQLNRMYTDTAQKLSINIESNIMPCSTVPRFKYLPISAPALSSRSTNKVSIPVTSNDASARNSWKAFTNGEQSQTSDLEENSNFGVAFKSFMQESTLKLGSILTDGQVGIFKDRSAAAMSTFGDILPAQAAGLLSSFTNTRSE