lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Recognizes the host polypyrimidine tract binding protein-associated splicing factor (PSF), which probably leads to its cleavage, diminishing the level of caspase-8 in macrophages.
Subcellular Localization:
Secreted. Host cytoplasm. Note=Is secreted into the macrophage cytoplasm. Might be secreted via a type IV pili apparatus that seems to be encoded in the same operon.
Sequence:
MVARHRAQAAADLASLAAAARLPSGLAAACARATLVARAMRVEHAQCRVVDLDVVVTVEVAVAFAGVATATARAGPAKVPTTPG
The following text describes a protein:
Function:
Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation.
Subcellular Localization:
Nucleus.
Sequence:
MTDKCLKTHQRPTGKASKHILERQRRARINQSLAELKNLVLSSLYHDNPEVYMDKSRERLDKAEILDLTVNFLKHHITGTRMESFERTGRETVLSRDQFVEDPRFVSHTVCPGCADGRCSMAYGPYGVSTPPPSPPHAQVFFAGRGVHHYAIPQYTAAPSSEIAKIVKKEPTECNETSSVWRPW
The following text describes a protein:
Function:
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MSDQISKGLEFEKKADKKLSGWGLFGSKYEDAGDLFEKAANCYKLAKSWDQAGAVYVKLAQCYLKANSESKHEAANAYADAGHAYKKTNIKECVACLEQALNLFMEIGRLSMSARYAKEIAESYEQEQNLEQAIAYYDKAADLFQGEEVTTSANQCKQKIAQFSAQLEQYQKAIEIYEGIARQSLNNNLLKYGVRGHLLNAGICQLCKGDVIAITNALDRYQELDPTFSSTREYRLLADLAAALDEEDVEKFTDAVKEFDSMTKLDEWKTTLLLRVKLLIKAKEDEEDDLT
The following text describes a protein:
Function:
Glycosyltransferase forming with EXT1 the heterodimeric heparan sulfate polymerase which catalyzes the elongation of the heparan sulfate glycan backbone. Glycan backbone extension consists in the alternating transfer of (1->4)-beta-D-GlcA and (1->4)-alpha-D-GlcNAc residues from their respective UDP-sugar donors. Both EXT1 and EXT2 are required for the full activity of the polymerase since EXT1 bears the N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity within the complex while EXT2 carries the glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Heparan sulfate proteoglycans are ubiquitous components of the extracellular matrix and play an important role in tissue homeostasis and signaling.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein.
Sequence:
MCAAVKYNLRGPALIPRMKTRHRIYYITLFSIVLLGLIATGVFQFWPHSIESSNDWSVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFHVYRCGFNPKNKIKVYIYSLKKYVDDSGVPVSNTISREYNELLTAISDSDYYTDDINRACLFVPSIDVLNQNALRIKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPERGPGPRRYFLLSSQTALHPEYREELDALQARHGASVLVLEKCTNLSEGVPAVRKRCHRHQVFDYPQVLQEATFCMVLRGARLGQAVLSDVLRAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAASSYEEWNDPPTVCHEGIQACWHALLLPKNRPRFVDVLIVFPSVLEKWGSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLAKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKSWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
The following text describes a protein:
Function:
Multidrug efflux pump.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQPEMLSIENEEITTHPAPSHAQLEKRVLRLAWPVIGENLLQTMLGVVDTILVASLGAVALAGVGAALQVIYVTTGALSALSVGVAVLVAQAYGGGRLKEASFLARQGLLWSILIGLPVTAIGLPLTPTLIGLFGLAPDVSQVGIDYLAVTMSTITTLTMMFLIGGVLRGVGDTRTPMIITAFANVINVIASAALIFGWLGLPVLGAVGSAWGSVIARFAGAILLVGVLWRGRNGVRAGGRGGWWPRMRVLRNILRIGMPAALEEVLIIGAIATLTPVVATLGTVPLAAHRVAINVLSLSFLPGIGFGLAATALVGQAIGAQRPAEARRIATIAMRWALIWMGGLGVLFMIFAEGLVRLFNSDPQLVAEGAAAVRVVALTQPAWAITFALGGALRGLGDTLSPLVISGSAIWICVGLALVIVLWWLPALWGIWLAFLIVGPFEALVFWRKWQQRITSWRPGSA
The following text describes a protein:
Function:
Common component of the spliceosome and rRNA processing machinery; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTKIKADPNRPEAQTELYKCIKKAIKQKQIQHGVKEVQKFIDKGKKGIMVLAGDTLPVEVYCHLPVMCEDRNLPYIYIPSKTNLGAAAGSKRPTCVIMVKSHKDYQEAYDECLEEVQALPPPM
The following text describes a protein:
Function:
Transcriptional regulator involved in extension of germ tubes into elongated hyphae and maintenance of filamentous growth. Regulates expression of UME6. Acts in a pathway that regulates maintenance of hyphal growth by repressing hyphal-to-yeast transition and allows dissemination within host epithelial tissues. Dispensable for invasion into both host oral epithelial cells and enterocytes, but required for epithelial damage.
Subcellular Localization:
Nucleus.
Sequence:
MERRQFNTSNIRNGTGRPRKTPRSKLYMVYPPLSGEDSTNPEPEEGSSQENNPTEPSSSQSNSVQNQDQSEDQSQLPQQESNTQQESNTQQESNTPSPRASNTSTETPAPLSPIQPGIRNIPSGLLLPQEKVGRLMGYPFYRDFNFTLNPERYQKLIYVFQILKNAARNHRNGASLLRKYFSLARRSKRTTDMFVTTIEEMRKRSLENSRKRELEEAQEREESNKRQHTESSAEPNAESSTESTTESNAESGAEPNAEPSAESTTESNVESGAEPNAESGAESGAEPTAESNAELKQRIWEILSYRLEQSNNETNNTGESNSTSQQPRQLPNNELIMNIRVLQKNTHAKPVLGRIKFTPDKSNKTSLTGSQNKVHSTNTQQSQKHPQQILTNSETHKPQQYSAQSQQQMVHQTNSHEPSQKRSPPPQQQQQKQPSVPTSSVPLQVSQKQNQQQQELPLPPQPQPQQRTAPSAVKQQQSMQMQPPPQQQQQQQRHQPLQQSPPTMPLQQQPVPPVQQVQTVPPPSSQPQTQLSQQQQQQQQAQLQMQVPRCYQYQNRPPSQQRQYSQTPQYNQPPPQQKVYALPPQQVYAPPPRQVYAQPTIACKQQYPQQLYEQAPQEGSSYQHHYQQVQQRQNQQPYMQSAPTYQQPHVQTPKSTRSNKQEKQRLPKGQEQVPKATRTMFEAFTGSNIAVEKLRQRTLDNGREPERLRTEYVNVLSSPERAAEKSTSRSKQSSNQKPVVKQQSSFPPPIKHQQTQEQQGNILPPVSQLLAIQSSTVTSRGSNASGAVMGSGNTQRVASRSFTNTFVAEAVVNNANNRGGPVPPTGPETNTRGGRASTRSSGRPRGNRSTQRAEGNVTGRVARSTDGSQSQNSGKASKISNIRNLLN
The following text describes a protein:
Function:
Possible role in granule neuron development.
Subcellular Localization:
Cytoplasm. Membrane; Single-pass type II membrane protein.
Sequence:
LHGAAFTSQIWKTLGTLQLVAAFGQLAIAIDLPGWGHSTNSRLTSEESRKNFLTLLFNELNITKPILITPSMSGVYSMPFIMEPQSETCKERINGLIALAPTATNVYSHAQFHRCDAKTYIVIGENDKNIGLFALANLKNMPNRKIFIMRNSSHACYKDQPTFWNEIIYHYNKEIIKRVDDSSHF
The following text describes a protein:
Function:
Involved in biosynthesis of fatty acids in mitochondria.
Miscellaneous:
MISCELLANEOUS: Present with 1360 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MKLLTFPGQGTSISISILKAIIRNKSREFQTILSQNGKESNDLLQYIFQNPSSPGSIAVCSNLFYQLYQILSNPSDPQDQAPKNMTKIDSPDKKDNEQCYLLGHSLGELTCLSVNSLFSLKDLFDIANFRNKLMVTSTEKYLVAHNINRSNKFEMWALSSPRATDLPQEVQKLLNSPNLLSSSQNTISVANANSVKQCVVTGLVDDLESLRTELNLRFPRLRITELTNPYNIPFHNSTVLRPVQEPLYDYIWDILKKNGTHTLMELNHPIIANLDGNISYYIHHALDRFVKCSSRTVQFTMCYDTINSGTPVEIDKSICFGPGNVIYNLIRRNCPQVDTIEYTSLATIDAYHKAAEENKD
The following text describes a protein:
Function:
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.
Sequence:
MLRRIKVGSNLNKKESLLDAFVKTYLQILEPISSKRLKELADLKISCATIRNYFQILSKEGMLYQAHSSGARLPTFKAFENYWQKSLRFETLKVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEKFLLELVGRSVKEVRSIAASFNALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLSKGLHFIEPDCMLVTRPVEFQNKRMQLLCVGKLECDYEGFFQTISEEE
The following text describes a protein:
Function:
Major thyroid hormone transport protein in serum.
Subcellular Localization:
Secreted.
Sequence:
MMPPSFFLLFMLAAVRTAVKCYPKPSGPEEGTAASSVKRNETFYEMATTNANFAFSLYRRLVAETPDRNILFSPVSISTSLAALSLGAQSASPTRVLEGLHFNLSRISEWEIREGFQRIVHILHLPTEHLELRMGNALFVDERLRPLVKSVDGAREAFAPETFPTDFTNASKAVRQIDSLVGKQTEGKIVDLVRDLAADTSAVLVSYLVFKARWKEPFDLIETRPGDFLLGEKKTVAVPMMSREAVYHRLIDEELACTALQLDYSQRALALLVLPEEGQMKRVEEALSPRTLRRWNRLLRKGMVRVFVPRFSISATYELEDFLRKMGFGDAFGTKADFPEISEQSDIKLSKALHGAVLGFTEKGTEAGATTGPSSGLRSDPIGDVPCMRFNRPFLFMVLEKDTRSILFLGKITNPSETTAHLSLPHLK
The following text describes a protein:
Function:
Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MGKKGKVGKSRKDKFYHLAKETGYRSRSAFKLIQLNRKFQFLQRARALVDLCAAPGGWLQVAAKFMPVSSLIIGIDLVPIKPIPNVLTLQEDITTEDCRQAVKKHLQTWKADVVLNDGAPNVGANWTHDAFSQVHLSLMALRLACDCLSRGGWFITKIFRSSDYQSLLWILQQFFKKVNSTKPQASRSESAEIFVVCQGFLAPDKIDTRFFDPKFAFKDVDGPVQTVSQLLSHKKPKAEGYAATSLSLYHCASLVDFLTVENPVDFLSKTSEIALDDTELEKHPATTNDIRECCRDIKVLGRKELRLLLNWRSKLRRHLARKLKEASKESAMEIILSSDEEEEKQKKDICDKDYNLEDEELHRKLAEVKAEELTALKRKKKRLLKTQRRQRERVELKMDLPGVSIADEGETGMFSLHTIGKNELLQTLSKGDMCAADSLILDDIHNDDVVFSNDETEELEGVDEISLASDLEDYELQEIHACEKSARNKRIQYPVKDCWMKDEVQINPLLVSLEDTSDREQRDTSMWFGKGIFSSLDLGADEDMEIKQMQLLKGNKMGNIPLKMPDQIRNKPLQLGLATSAAKCVEKSGAITSSTAKVTEFMQRSEETSSSKVCSKDISGKNDSSNSDSDNSEDEFIAKTMERSAGKRKEQGEEDKADFEVVAIERTVKRSRVVGPDGLALGTVIATSKKSTRDLIDGSFNRRNFNDDEDELPDWFVSEERKHRIVQVPVDRHMMEDYRKRQRELNARPIKKVAEAKARKKRRTLKKMEQMKKKAEAVVNTSDISEREKAAQLRSIYRKGVLGKEKPQVTYLVAKKGVGRKVRRPAGIKGHFKVVDGRMKKDMRSQRKKK
The following text describes a protein:
Function:
Seems to function only as a co-chaperone, along with cpn60, and in certain cases is essential for the discharge of biologically active proteins from cpn60.
Sequence:
MARRLIPSLNRVLIEKIVPPSKTSAGILLPESSSKLNSGKVIAVGPGARDVSGNLVPVCVKEGDTVLLPEYGGTSVKLGEKEYASTFLALFVETMVFDSNFPALFIPTISILLEIAVYLCQIHTSLSSICLEMKTFWELYMMIDYQSNSTVDCLCFLLELHSAFLFLMVWRSGNYCSLRVLGLSEDFKS
The following text describes a protein:
Function:
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of pyranonigrins, a family of antioxidative compounds. The first step of pyranonigrins biosynthesis is performed by the hybrid PKS-NRPS synthetase that condenses 6 malonyl-CoA units to an acetyl starter unit, to form a 1,3,5-trioxotetradecane-6,8-dienyl-ACP. The enoyl reductase (ER) domain of pynA is likely to be functional during the first two rounds of polyketide chain extension, to generate the saturated C-C bonds of the alkyl side chain (Probable). PynA subsequently forms the amide bond between the acyl chain and L-serine. Although pynA has a terminal reductase domain, it appears to require the thioesterase pynI for the release of the straight-chain intermediate from pynA via the formation of a tetramic acid pyranonigrin J. The methyltransferase pynC then coverts pyranonigrin J to pyranonigrin I via N-methylation. The FAD-dependent monooxygenase pynG catalyzes an epoxidation-mediated cyclization to form the dihydro-gamma-pyrone moiety, followed by pynD-catalyzed oxidation of the alcohol to the ketone and enolization to yield the characteristic tetramic acid-fused gamma-pyrone core of pyranonigrin H. Pyranonigrin H is substrate of pynH for dehydration-mediated exo-methylene formation from the serine side chain to produce pyranonigrin E, before the oxidase pynE reduces the exo-methylene of pyranonigrin E into a pendant methyl to form pyranonigrin G. The FAD-linked oxidoreductase pynB performs the reverse reaction and converts pyranonigrin G back to pyranonigrin E.
Sequence:
MWRIPVIVALVAGLLYWVRKQGSQPSRKIPQPRIGLPVVGDAHAFGKSPISYIRQATARCGPVFQINLLLTKIVMLRGAQLNRFYLDTREEVWSFGDGMGLFLEKVVVPGYLSHLKEMVSSLNRGVIRSIALEHYTRIAGEEARKIATNWAEKPDIEVFEQMSRYTHRVIVRCLMGQDFYDHHLDELLDLLHRMEADIGHPFHFLLPNWVPHGPARRLHHARDRMAAIFNERLQAREQNPEKWQDSLDYIAYTLKDSRTAHLRQYFAAHHTLLMFAAHTSTVASIAWTVLELLRNPTHLEALKTALATDADIHRSPTLIATLKETSRRYSGVNMIRWARQPHQLPADAAPGKGNIVVPENCIVSISPYLTHHDPETYADPHIWDPTRWLEGGRLSETQKSNRSEVTYFPFGAGCHRCPGEQMAGMIAREMVAHMVKTYDVRWSSTGPPEDFEQLDFSRVGSAWLKGDARVTVKRDKQGMEEA
The following text describes a protein:
Function:
Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.
Subcellular Localization:
Nucleus.
Sequence:
MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY
The following text describes a protein:
Function:
May play a cooperative role in NF2-mediated growth suppression of cells.
Subcellular Localization:
Cytoplasm.
Sequence:
MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG
The following text describes a protein:
Function:
Required for pectoral fin formation. Together with tbx5b, involved in eye and heart development. Required for the looping stage of heart development. May bind to the core DNA motif of promoters.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus.
Domain:
The T-Box domain binds to double-stranded DNA.
Sequence:
MADSEDTFRLQNSPSDSEPKDLQNEGKSDKQNAAVSKSPSSQTTYIQQGMEGIKVYLHERELWTKFHEVGTEMIITKAGRRMFPSFKVKVTGLNPKTKYILLMDVVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRIHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSTKEYPVVPRSTVRQRVGSSQSPFSGDVQGLSASGAISSQYSCENGVSSTSQDLLPQSSSYHEHTQDYHCIKRKVEDECPAGEHPYKKPYVESSSSEDDHYYRPLSYSQSLGLSGGAPYRPESSQRQACMYASAPQPPEPVPSLEDISWPGVPPYSVPQMERLPYQHHFSAHFASRQMPEAHGMYASSVSHQCSPSGGIQSPSAGLQGNEYLYAHGLQRTLSPHQYHTVHSVSIMHDWNEAS
The following text describes a protein:
Function:
Serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1.
Subcellular Localization:
Cell membrane; Lipid-anchor. Endomembrane system.
Sequence:
MNYEEICVGSDLSLYSFQRRWRPSTISNRRVCSNLFPMDGNPRLSCFGLMKSSRDGKSYIALTWHLLLQRNLLTGRVTPESVLCFQFWNRFARSH
The following text describes a protein:
Function:
Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
Sequence:
MKVLITGAGGFLGQYFVKEFQDHDVIPLTHKDINIEDKNTIEKIIELKPDLVIHPAAIRSPDICERDPDLAWKVNALGTKHIAIACSILDIPLIYISTDYVFSGDKNSPYTEFDTPNPINVYGRTKLQGELFVKEFCEKYFIIRTSYVFGEYGNNAFTQIYRSLKEGKEIYLSNYHFASCTYAGDLVRKVKELSFTKLYGTYHIVNKGIITRYDFAWKVAEIFNLPKDKIIKLTSENFNQPAPRPLYSVLRNYVLELYHMDDMEHYEEILKKISFLCF
The following text describes a protein:
Function:
May modulate immune response and may play a role in inflammation. Down-modulates STAT3 signaling throught direct interaction with IL6ST, resulting in the inhibition of phosphorylation of STAT3 at 'Tyr-705'. May negatively regulates AKT signaling by modulating the activity of mTORC2 complex through RICTOR interaction (By similarity).
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MRGPIVLHICLAFCSLLLFSVATQCLAFPKIERRREIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPGITSQEPGLEEGNMDLLEGATYQVPDALEWEQQNQGLVRSWMEKLKDKAGYMSGMLVPVGVGIAGALFILGALYSIKVMNRRRRNGFKRHKRKQREFNSMQDRVMLLADSSEDEF
The following text describes a protein:
Function:
Transcription activation of genes for enzymes and proteins of quinate metabolism by binding to a 16 base-pair sequence (consensus 5'-GGATAANNNNTTATCC-3') in front of each qut gene.
Subcellular Localization:
Nucleus.
Sequence:
MSSDTRQTSGGNARSKRRLTDAVDEDGRPTATAEDPTSNPKRQRVSRACDSCRSKKDKCDGAQPICSTCASLSRPCTYRANPKKRGLPTGYIRTLELLWGLVFNKIQGSEEVVRTLLRAANIPSHLATMGKESEGSDTLLSSWKNSIVLKEIERLLTFLEQPEGDQERSARGEIDSPADAEESSVLSPETLEWQLPDSIAVASQSPLASGPSPVRLPRPSTTRLVRDSGTQTIPLGEIEDLTTNGSSHDRPVIASNSAREEHRLPPNPWPLLDIYFSYTQCWFPILEKHDILRTAFRQGDDDQYNSPSAAGDNAALWAVLALASIQQTSISTTRQLSDLPEDRPDPDQLYAKARSLIPTESGTYQLGHIQALLILSLIKLGQQDCAAAWMLVGQAVRSAQSLGLNDPSDATGVEKTAGRSKHVFLGCFVLETLVAAKLGLLPSLRKTDLTKVGLINEDGLEEWHPWEDQTGLRPIESSRSFQRGPLHALSTFNRLLSLMCILNELCCVRQTPANSMSYLGTLERQLQLWVSALPTSYRIDLQTVSTKPASPHIFGLEMMYEAVATAISLQLAVQKNERNGLRRASEGSKRLVSLLQAYMETYSLSATCPTFGIALTLGLPLPCMKKTAPWAFEASHGINHKLQSFSAHLATVWIHNTGSQRRPRHATQQGTHPRSPMAISLPGNNMRLTNLIEESRTGNLSTTDSYLSPTWMRTSNDENAVLSLPTPASSLNIASGVETNPTSQQITHQHRSSVVGKPNSALIMSDLTTPFPASGHHYQQTYDDASLHFNSLADIESTSSAQRPRIAPDLDALFDELASLDGTDR
The following text describes a protein:
Function:
Member of the two-component regulatory system DctB/DctD, which regulates C4-dicarboxylate transport via regulation of expression of the dctPQM operon and dctA.
Sequence:
MSPFAPFDAQTQVLLIDDDPHLRQALRQTLDLAGLKVATLDDARQLDTAQCKDWPGVVVSDIRMPGIDGMELLRQLHEQDADLPVILITGHGDVPLAVQAMRGGAYDFLEKPFPSDALLDSVRRALEVRRLVLENRTLRLALAERHELHGRLIGRSAGMQRLREQVGSLAAIQADVLVLGETGAGKEVVARALHDLSSRRDGPFVAINAGALAESVVESELFGHEAGAFTGAQKRRIGKFEYANGGTLFLDEIESMSLDVQVKLLRLLQERVVERLGSNQLIPLDIRIIAATKEDLRQAADQGRFRADLYYRLNVASLRIPPLRERGEDIPLLFRHFAEAGAMRHGLTPRELDAGQSARLLAYDWPGNVRELQNAAERFALGLGLSLDDGVLPDAADEPHNLSAKVEAFERSLIAAELERPHNSLRSVAEALGIPRKTLHDKLRKHGLPFNTPGENPPDDGE
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MTLPSTPEDHHLLVDDFYFSALYDAEEIFPISDEKYAEELQLQEALYSSIISSTTKVKNEVIQVNVDVDGDTPLRTLKKKHKEIGESSQVYCGICMDAKSGEEIFRNRNCSHSFCSDCIGKYVTAKIQENISTVKCPDTKCKEVVEPQYCRSIIPKEVFDRWENAIFENSVLRSQKFYCPFKDCSAMYIRDAGEVVTVSECPYCNRLFCAQCKVPWHSEIGCNEFQNLKKYEREREDLMVMELAKNKSWKRCPKCDFYVERIDGCAHISCMDAKPILCGNEFCYVCGSTWSCQHYNCEPL
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Membrane.
Sequence:
MPKLTIDHILVEVPPGTSVLEAAKTAGIWIPHFCYHPALGSVGACRLCAVKLLDGPVKGIQMSCMLPAQDGMVVSTTDPEALKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGHGIRRFEGKKRTHVNQDLGPHIQHEMNRCIQCYRCVRFYQEYAGGSDFGVMGSARRVYYGRFEEGELESPFSGNLVDICPTGVFTDKTARFRARYWDYEMAPSVCPWCSLGCNTVPAARYRELLKTMARENPAVNGHFICDRGRFSNAAVNDPVRPRVPLVDGEEVSWAAAIDATMLRIEEFMELYGPGRLALVGSPRLPLEGSVLLARLAGLIGTEYLCYFAERDEGERVAAAVSLLADGRAASMADVRKADCIVILESDLRDEGPMMLLAVRQAWRSGAPVFLVGTHAPLEQARAVSIEAIELSIIEEVPLAIFERAVVICGTRNNPPAATELLAHTDAKIAYLFPGPNAFGAGLLAKEHGAVTLAEAVASGRVKGIIAVEADIPEALLAGVPFVVAADWLPTETVRRAQIVIPTAAWVETDGTYVNFEGRAQRFRKVMAPGLPIRGLPARYHASPDKPAPFHPPRVHRSAPPGGELRPAWRFVAELVERFGGEAVTGGVPDGGSCCGTSTRKGEGKRCCSEKCCAKLNHISITGKSGLLNRYFQRTVHYAAAPGV
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of toxin ParE (By similarity).
Sequence:
MAKNTSITLGEHFDGFITSQIQSGRYGSASEVIRSALRLLENQETKLQSLRQLLIEGEQSGDADYDLDSFINELDSENIR
The following text describes a protein:
Function:
Catalyzes the synthesis of beta-citryl-L-glutamate and N-acetyl-L-aspartyl-L-glutamate. Beta-citryl-L-glutamate is synthesized more efficiently than N-acetyl-L-aspartyl-L-glutamate.
Miscellaneous:
MISCELLANEOUS: N-acetyl-L-aspartyl-L-glutamate (NAAG) is the most abundant dipeptide present in vertebrate central nervous system (CNS). Beta-citryl-L-glutamate, a structural analog of NAAG, is present in testis and immature brain.
Subcellular Localization:
Cytoplasm.
Sequence:
MCSSVTGKLWFLTDRRIREDYPQKEILRALKAKCCEEELDFRAVVMDEMVLTVEQGNLGLRISGELISAYPQVVVVRVPTPWVQSDSDITVLRHLEKMGCRLMNRPQAILNCVNKFWTFQELAGHGVPLPDTFSYGGHENFAKMIDEAEVLEFPMVVKNTRGHRGKAVFLARDKHHLADLSHLIRHEAPYLFQKYIKESHGRDVRVIVVGGRVVGTMLRCSTDGRMQSNCSLGGVGMMCSLSEQGKQLAIQVSNILGTDVCGIDLLMKDDGSFCVCEANANVGFIAFDKACNLDVAGIIADYAASLLPAGRLTRRMSLLSVVSTASETSEPELGPPASAAVDNMSASSSSVDSDPESTTEREMLTKLPGGLFNMNQLLANEIKLLVE
The following text describes a protein:
Function:
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
Sequence:
MSFKKIIKAFVIMAALVSVQAHAGASQFFKDNCNRTTASLVEGVELTKYISDINNNTDGMYVVSSTGGVWRISRAKDYPDNVMTAEMRKIAMAAVLSGMRVNMCASPASSPNVIWAIELEAE
The following text describes a protein:
Function:
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
Sequence:
MGGKGGHEVGLLLWNSRDAIFSLFEELLWVYKLVSPLKLGMAEATRVCNALALVQRPLVLKFTLWISSLTVERFNFTEGTQPDRRYLVVFMMVISNVCANIPIVVCGDKVDVKNRQVKAKQLSFHRKKNLQYYEISAKINYNVEKHFLHLSRKLLGNASRNE
The following text describes a protein:
Function:
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
Subcellular Localization:
Nucleus.
Sequence:
MGWRRKRKVDEKGSTEKGKSKKKATAEATAEPAAGDNAAVDKDDIEGNRTHGAFFGCYLLSSLNPKKKNSTYIGFTVNPARRLRQHNGELTSGAYRTKKMRPVEMVLVVYGFSSMVHALQFEWAWQHPTVSLAVKEAAATIKNRRSVKGKIALLYAMLKLPKWNKLPLVVQFVSSRHVVHKLGLPPLPDHMDCLLAPLSSLRIKVDETAQDPPILDPPSEPPPNEPSEVPQAYAGGQKDQDGASSLDSLGADSPPPSVPPRNPRLETPSSPPGASGWADPLADWDWLDQDKAEWDNSPGSWGEQEQEKADPFATWQRLKAPKDVSMASLKRGRRKGASLVGGTGRGAEPESDPVTSWSERGEGSDADWALGEREEGALDRREEVKGRVRSDWQPTGCAGAVEADEESDVGAGRRSERDDSVDFELPLWQRLERARDGGTKAGTANGVRRRDTVNLVGCDKESLSREEKSKRRELQTRRGRDIGGPHCSQGPPSLMGVELVVLEGSPVLQKAMMTDKGARRAQVRDAIATEYRAAQSVHKGMHEEVGKWVLPDITRLSRERVVIDLDP