lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Miscellaneous:
MISCELLANEOUS: Present with 3150 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MENTLGEGSTVNASVDVDQHGNDNNSDSNANAAVAGVANTDTAGEESQQQDESLKDEATVPNTRDAESEAITVTAKQQPTMQANKLDSQETPSTEESRAQNVFGQDNEDSDNLFGETESSVSNNEANTPSIPTNPVDNENNKPAIKEDSTIQDSNGDVKNMEDVKIQKEEEPENNTVIEGVKEESQPDENTKEMDEVEEDDEDDDQPMISPDNSIFGDTKSESKQLGNTSSVANTPSEIPDAHKAEQEDIIEKTESVDKKVDSGEERNEQEREIMNDHSKSANPKKTTITRVEPETFEIPQAHEIVIPSYSKWFNLEKIHSIEVQSLPEFFTNRIPSKTPEVYMRYRNFMVNSYRLNPNEYFSVTTARRNVSGDAAALFRLHKFLTKWGLINYQVDSKLLPKNIEPPLTSQYSTRHDAPRGLFPFESYKPSVQLPDMAKLKKMMNTSDSESTLYKYLKESKRKYDEITHPPSTTDDENGDKNDNGGKMNNEVSTSTSMTGDANLLEEGETSRPLKKVKILEQIDENWSKEDLQKLLKGIQEFGADWYKVAKNVGNKSPEQCILRFLQLPIEDKFLYGDGNGKGDNDNGLGPLKYAPHLPFSKSENPVLSTIAFLVGLVNPKTVQSMTQRAIQSAESIKSQKEEISDQKPIEHIKEGSEIAISSLGYRSHIFATNEERQMNFLTNELIRLQMEKLDAKLNHLKKLEKFMELERKTLERQQENLLIQRLNFNQNSSKIVNVLSKCLNLISDSNINNSSVAEKEEIRSQIDHFKSMLSKPETLSIGKNPFNKPNIETGENHNGQSISNENDVKPISIEAPQFYRYWSA
The following text describes a protein:
Function:
Required for growth at high temperatures, probably by acting as a chaperone during heat shock and targeting heat-denatured proteins for degradation by ClpP. Required for biofilm formation. May act as a chaperone regulating CtsR activity.
Sequence:
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHYTPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNTPTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVMSLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEYRKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASSKVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNAQNGMSTSLSEEDIAEVIAGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAESMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLTDTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELKEIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDGKEFKYDIAEQTSETKTPSQA
The following text describes a protein:
Function:
Cargo protein of a type 1 encapsulin nanocompartment possibly involved in protection against oxidative stress.
Subcellular Localization:
Encapsulin nanocompartment. Note=Consistently identified in encapsulin nanocompartments isolated in situ.
Sequence:
MQSSSLDPVASERLSHAEKSFTSDLSINEFALLHGAGFEPIELVMGVSVYHVGFQFSGMRQQQELGVLTEATYRARWNAMARMQAEADALKADGIVGVRLNWRHHGEGGEHLEFMAVGTAVRYTAKPGAFRRPNGQAFSSHLSGQDMVTLLRSGFAPVAFVMGNCVFHIAVQGFMQTLRQIGRNMEMPQWTQGNYQARELAMSRMQSEAERDGATGVVGVHFAISNYAWGVHTVEFYTAGTAVRRTGSGETITPSFVLPMDS
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as a scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.
Subcellular Localization:
Nucleus.
Sequence:
MAGVFPYRPQAPPMPGPPSVTPDYMSEEKLQEKARKWQQLQAKRYAEKRKFGFVDAQKEDMPPEHVRKIIRDHGDMTNRKFRHDKRVYLGALKYMPHAVLKLLENMPMPWEQIRDVPVLYHITGAISFVNEIPWVIEPVYIAQWGSMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNILDVEPLEAIQLELDTEEDSPVTDWFYDHLPLRDNRKYVNGSTYQKWQFTLPMMSTLYRLANQLLTDLVDDNYFYLFDLKAFFTSKALNMAIPGGPKFEPLVRDINLQDEDWNEFNDINKIIIRQPIRTEYKIAFPYLYNNLPHHVHLTWYHTPNVVFIKTEDPDLPAFYFDPLINPISHRHSVKSQEPLPDDDEEFELPEYVEPFLKETPLYSDNTANGIALLWAPRPFNLRSGRTRRAVDIPLVKNWYREHCPAGQPVKVRVSYQKLLKYYVLNALKHRPPKAQKKRYLFRSFKATKFFQSTKLDWVEVGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLCREVLRLTKLVVDSHVQYRLGNVDAFQLSDGLQYIFAHVGHLTGMYRYKYKLMRQIRMCKDLKHLIYYRFNTGPVGKGPGCGFWAAGWRVWLFFMRGITPLLERWLGNLLARQFEGRHSKGVAKTVTKQRVESHFDLELRAAVMHDILDMMPEGIKQNKARTILQHLSEAWRCWKANIPWKVPGLPTPIENMILRYVKAKADWWTNTAHYNRERIRRGATVDKTVCKKNLGRLTRLYLKAEQERQHNYLKDGPYITAEEAVAVYTTTVHWLESRRFSPIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKRHLLTQRAFKEVGIEFMDLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPADTEPPPLLVYKWCQGINNLQDVWDTTEGECNVMLESRFEKMYEKIDLTLLNRLLRLIVDHNIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFASFIVQYYGLVMDLLVLGLHRASEMAGPPQMPNDFLSFQDVATESAHPIRLFCRYIDRIHIFFRFSADEARDLIQRYLTEHPDPNNENIVGYNNKKCWPRDARMRLMKHDVNLGRAVFWDIKNRLPRSVTTVQWENSFVSVYSKDNPNLLFNMCGFECRILPKCRTSYEEFTHKDGVWNLQNEVTKERTAQCFLRVDDESMQRFHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGGKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTKEQSQLTATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLPSQLPQHEYLKEMEPLGWVHTQPNESPQLSPQDVTTHAKVMADNPAWDGEKTIIITCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNPKGYLPSHYERVQMLLSDRFLGFFMVPAQASWNYNFMGVRHDPNMKYELQLANPKEFYHEVHRPSHFLNFALLQEGEVYSADREDLYA
The following text describes a protein:
Function:
Involved in the lipid remodeling steps of GPI-anchor maturation.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MAAAAATPPIPAPNPTDVWVGGSWTVDCSCGVTFDDGEEMISYEQFWENERAKLGLQPVNYHGKWPLKRASVFQEPLSAALSALTLVVQFNGWLSFFLLLYYKLPLRPETHKTYYEYTGLWHIYGLLAMNSWFWSAIYHSCDTIWTEKLYFSSDAAFLGYSLILTILRTSSLRDEASRVMVAAPILAFVTTHIMYLNFYELDKGRRKDLNILKQAFISYQLVASASTMHISLSAEFDYSVGPTIGLWGNENKSFEAIRTNWFCMALHITAMTQLLKGINSYRSSLKVPALSENKNTACLAEQLARQFKGHECTNTFLDATIFAFWTKTSVDIEPKRIRLKSSSYTSNTMLDTVTAATVQVGICCSVMLGIVP
The following text describes a protein:
Function:
May be involved in sperm differentiation and proliferation.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus.
Sequence:
MENSEEESVGVAPQEFRELVLLESSLLEGEPSVQAPEQSPGAPAGDNQMVKPLVICGPVEDWVPLAEVLHHPDTCEEGDEATMAELKVTEVVDVKNEGEEVKDQKQEGEQDQQPELEKNPEQACDSKDQQGIQRLPLSGGGPAERRSKMEELELLQLELSFVNARCSGAFARIKAKVAKMRRPHFDRRKTIIQGIPGFWAKAMMNHPQMSSIISNQDEDLLSYMLSLEVEEYNPGLRMCRMMFFFSENPYFRNDIVTKDYQLSIIGYKESDSSTIEWIGQAEHGYANCMQDTTRLTFFNWLCAHKFPGSNRIAEIIMDDLWPNPLYYYPKEDHS
The following text describes a protein:
Function:
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix, basement membrane.
Sequence:
MGSSMPGLGGHGPSLLSMEVLLLLLVKMPNVPAQELPDLLHPGCSEGSCYPATGNLLIGRARSLSATSTCGLHGPQEYCIVSHLQDSEKCFYCDSRMTGDRAGHRIENVIYLSRQDGEKTWWQSENGVEDVSIRLDLDGEFHFTHLIMKFKTFRPAALLIERSADSGRSWKVYRYFAYNCSKLFPGVPTAPGIRVSDLVCDQRYSDIEPSSQGEVIFKVLDPAIQVDDPYNQEIQDLLQITNLRVNFSKLHTLGDNLLDGRPQGLRQYYYALYELVVRGSCFCHGHASECAPAPGVPPGSPGMIHGLCVCKHRTSGPHCERCQDFHHDRPWRPAEPSDPHICRECECNQHSRSCHFDMAVFLASGNVSGGVCDGCQHNTMGQHCQLCRPFYYRDPRADLRSPVACRACDCDPAGSLDGGVCDGRTDVALGLIAGQCRCKVNVWGQRCDSCRQGFYGLSQANPLGCQPCRCDPQGTVAGSAPCDHVSGECYCKRFVTGRFCGQCLPEFWGLSNDLAGCRPCTCDFGGAYSNRCSREDGLCPCRPHLSGRRCHQLQSGYYCATLDQAKYEAEHAQGHPPTDPLLPGAPRPEAPSDCPQDPSRPQSRHRPRLRRQRSPTRSPPSHSPARRSRQLLPKPDVEPVPRERVGTAPTWTGPGFARVRDGAGLSFHIHHVPLALGYDILLRYEPQSSEDWEAIVSVRASTLPTSPRCGNVLPSEQLYHEALPHRHRYVVLARPFCFEPGTHYEVVLRVQRAGVTQWHPEAYILLDSLVLLPRVLELPGLRTGDPGAAQRHQDMERYRCLEAFRMVTLPVLAESCAELLCSISALLHDGALSCQCDLQGSTSTECAKLGGQCQCKANVIGRRCNQCAPGTFGFGPTGCSECRCSPEGATSRFCDPVSGQCQCRLSIMGRQCDRCQPGQWGFPQCRPCQCNGHAEECHPHTGACQDCRDATAGRHCERCLDGYYGDPVLGSGQQCRPCPCPGYPGSRHYHGSSCQADGHTGQIVCLCAPGYAGSRCDRCSAGYFGRPVEEGGDCRPCQCNNNIDPSDPAACEPRSGQCQRCLHNTQGPRCAHCRPGYYGNALQRSCRRCTCNLQGTVPTRCPLSGPCYCDRITGHCSCRPHVLGRNCDRCAPNFWNFGGTHGCEPCSCHPTRSLHLSCNTFTGQCHCRAGFGGRTCSHCQEGYWGDPELECRACDCDPRGSESLQCHRLTGRCSCREGFTGSRCSVCTRGFQDSFPHCPPCHPCFTHWDQQLGLLRKHLAWLNQEAEALRLGGPGPEVSSARLRSLEEQLRQVQGLLGAGHFHETQLQPLTRQLDNFRREVAALGLGLLAVEQHMVSSNLQVEGQQSRLGKLARELNHLNGSATRLWEQFRDAVEARTSETIGHILAAAQASRDAERQTNTSLQGPNSALGQAHSTRRQTEQLLQQTEKTLRRGMAAQRTKLQGLLTDTKALSIFTANQRICGARGEKGCALSPCGGAECRDSLGRRHCGGPNCPGALPVSLKALGTAQNVSRALGHTTEQLGQLAHQLLEIQAVARAAQTQAEETLSRAQAARGRAGKGTAQLLDFIQRIRLFLMEEGADPESIELVARQVLAISLPSSPEEVGHLLEEIRDSLRSLDGVDRLLNSTARAMASAQGLLERGQQAREWAEGVKGTIMETQGTLEMTRKSMRAAEQVLRKAKQALRGVESRVREVDRKLQQVTWAVDMDTALEKLSREVANLQTKMADNRKLAQAAEGKAGHAASTAKKLGKDMQMVKQRYMELQGQVGSLGGGMNKAWERARQVQHEAQELLRKVSGSKTQLEGLEKRFERNEKELEEKVSQLQTLEKQVSGLLEHIRQEANAYATC
The following text describes a protein:
Function:
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. Required for cardiac differentiation and maturation.
Subcellular Localization:
Nucleus.
Sequence:
MLPSQAGAAAALGRGSALGGNLNRTPTGRPGGGGGTRGANGGRVPGNGAGLGQSRLEREAAAAAAPTAGALYSGSEGDSESGEEEELGAERRGLKRSLSEMELGVVVGGPEAAAAAAGGYGPVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDPTTDQRMSATGFEEPDLTYQVSESDSSGETKDTLKPAFTVTNLPGTTSTIQTAPSTSTTMQVSSGPSFPITNYLAPVSASVSPSAVSSANGTVLKSTGSGPVSSGGLMQLPTSFTLMPGGAVAQQVPVQAIHVHQAPQQASPSRDSSTDLTQTSSSGTVTLPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLADGSLTVLNAFSQAPSTMQVSHSQVQEPGGVPQVFLTAPSGTVQIPVSAVQLHQMAVIGQQAGSSSNLTELQVVNLDATHSTKSE
The following text describes a protein:
Function:
Probable component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI-anchors for cell surface proteins. Ras may inhibit the enzyme activity of the GPI-GnT complex via the association between ERI1 and RAS2.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MRPRDQGFLVLGFTYSVLLISLATFYWLRNNDSFLHYWCVLLLCPATLWLWALIAWCDSEMFASSKDE
The following text describes a protein:
Function:
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
Subcellular Localization:
Nucleus.
Sequence:
MPVKVDVKIIGTYKKLKDKSAEVGGLPRLLNEDPHRFGLLEETDQMDLKKGWEEFNDEGYGDTFDSLFDYIRKTSKKRTSLEKALGTDFVLTRRILLLFAKKSVYKTFYVIRAVRRNGVIFLCDEVSENKGPSVMRVYGHKFEQYMTLNRVGEPYDEDAPVVNSEYCRAVFQTSLACGNEEIKVMYSEVVKAEDKGKGKVVAINETSLDLKTWLYKRSLGVYLQSYFGGSSYIVKGTTNNDNVVYKVDKIPTEEIPKMNVFWKPQACFEKVFDILQEIKTRLENDDDAIVIRSVGWDISYEPEDARKCDFVDPEFLRKFH
The following text describes a protein:
Function:
Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Required for brain and eye development.
Sequence:
MELLGVRQPFGPQFQEEKYQMLELNHRLESYLGRVKLLEEENKLLREEIHTLKSSRDPAGQRKAQEEALSQARRMMEEAWRKKDCVELEVENLMEDMEKVSFQRKKVKTAQAEAQRKLTESRKELEEERRAQIWLREKVGQLEKDLMLQMQVHQENMETMQASLKQTKQVLMAPQRVQATSIPDLGQEYGYKAAQAWQEAANNYQKQVGRLEESLNQTKANMTKIYQEKRESQRQVQHLAKELESTRIKRQMLEKHAMQQREEQKEELQHLQAQVNTLELEKDCLGQQIDSLMLDRQHLLQVKMSLGLEVATYRALLDSEGLRIDRPTPNKTSSTVFLDALSKPTGIQSTSQTTAASCLLSSSVSTSHRSIASSRSLLTSAAPSWTLTRGTPQRPPSSTSMTEKTEDHISEETKRSAEESVDQLQQEKVQQDWTLESTLPKTSAEPKPELQPEEIKVEDEANEPQQAHMVESKTDESELTSVPAEQQGSMSQTPETKSWAGHFNDPAEVSEDGKDEDTEVSVEMARISHAPKVAWEEIKSAVEDEKDDASEMDVRSEIISESHTFAYGDAENDSNTLTSSHISQNTNALASSFLEQGTLDSASYFGYEATNENLMKEEELDNVSNISEEVTEQLNSETEAAIDSINEWDRQEESEPENETKVMTSYFEVEEGEMSINTDTKDKTEDDIEREELEVTEREILVQSAGGMLGVDLPNDTDHQDEHNLPQIELNEDQSEAEEENQKEKQCDEDDSPNISASLKTDPGEGDSYSQEHTLADTRPLIRYKSDEETSHHIGETSDSEDEKERIDQGHLNEKRFNTMEDLTEEPDMEVTGKMRLEDLVSNEEAAADDVASVMFQKVSGDHESLDVVVQESERKGNLEKEDSGDADNMRDNKEEDVSVFEQNENQQLTEHQHVHTEQVEDKPVHSHETQEHVNTEFSSTFSERSQQEQLEESSLTMFEDEAATKEAEDSDVSMHTNIDLIDSRSLESEINGQPDIMTSDMANSECNSSEDESPNASQCFQNTSLLAAATPNEQPLTFTNEVSKADYVSDNNDVPEEVLSEEKSTDEPKASQIDDLENFNIWGESTSISDAAQTTHASMDEHSSISPVNENLESSNKIPSVAENIFGHFEEHLERSVESFPEKEVTVMDFENNDLGEEFQSKQMKSEIHSFFSTSLKQDFWSEGKMEMAATYDPAKTEDLNQAMVFGEEWREIGVQSANGDTKEEMEILKIRDDKQKDGQPAQSKIVQSDDSADEGDSWSSGDE
The following text describes a protein:
Function:
RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4 (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus. Absent from the nucleolus (By similarity).
Sequence:
MEVVEAAAQLQTLKFGGSGPGSAASPPPEERPDAEQAEQAPPAGEQPPPAPSSDAGENPPPPSGPCATAPDAAEPLPELQDSDSSDSDSDSETDSDSSSSSSSSSSSSSSCGSLPPVLSDGEEDVQVEKENKNFPLKTKDELLLNELPSVEELTVTLPEDIALKPLGKVSSIIEQLVIIESMTNIPPVNEDTVIFKSDRQAAGKIFEIFGPVAHPFYVLRFNSSEHIESKGIKIKDTMYFAPSMKDFTQYIFTEKLKQDRGSDASWKNDQEPPPEALDFSDDEKEKEAKQRKKSQIQGRKKLKSELNESGEDFGEVHQNWNANSSSEHSKGYHNREFTRGFPRGRYSRGSHGRPPPQQYYNSDPMASQESLGFPPQRQDNPVMPHYPFPPPMFDMHNFPLPPPPPPPPTVSMGWAAPSMTSHPVLNLPYSLPPPPLPPPPPPPSPGESNSSHFGSYY
The following text describes a protein:
Function:
Potential transcription factor that may play a role in the regulation of genes involved in cell cycle G1/S transition. May bind to regulatory elements of genes, including the promoter of the transcription factor FOXO1.
Subcellular Localization:
Nucleus.
Sequence:
MVGSEVVLTQVQPCFQLLRMGSSPGQSSINANSTASRDLYTFLPDSPCCIYRLGAQHDLCDVPLPGKPAVHAKIHAERELSGDWKVNLESCTHFGIYINDVHLLQGQRMELSDGDLLRFQEKSDVSPCQSSSPDTYFLFQRVRVRPLDFSAITSPRARSSFPGFTPVLATQRLSGGRGGSPHYTTGATVILNSIGSISKMKRERMQGIGLMGGAVELTKPSTPDLPLPSRTGVERRHSRRKAQHQVLCELEEDEEDGQVEVGEMKKRKRGRRKEERKMVNHEQTGRKPRGRPRKHPIPPSVVSQTVSNAEPCAWRSCCLPQEETVSWVQCDHCDSWYHVVCIGRSLTSLQDTDFHCGCT
The following text describes a protein:
Function:
Alcohol acetyltransferase that catalyzes the synthesis of ethyl acetate from ethanol and acetyl-CoA. Can also function as a thioesterase by hydrolyzing acetyl-CoA in the absence of ethanol, as well as esterase hydrolyzing ethyl acetate (By similarity).
Subcellular Localization:
Mitochondrion.
Sequence:
MSRLAHNKALPYKIIVDLSFHRTRLPSDVSSLIKFEQRPAIINIHGLLGSHVMFHSLNKLLSRKLDADIFSVDVRNHGISPKAIPYDYTTLTNDLIYFIETHIGLERPIYLLGFSMGGKIALLTTLYKNINIRKCISIDLPPYETPELDPMILQNYDLIMRIIRRDVKILRGSPSWQKKVLELFKSLECNKRKCGGAVALYFANGFLSVKSNNVHQAQLHYEQQQHDPYINYSMPLSSMPNLLDEVKKWPDLSNQRDFFQKGTASRKVLFMKGLQSNFINNDYSLLRYNFPCADVREFNTGHNLLLENPEDSFKCILNFFAEETLDFE
The following text describes a protein:
Function:
May regulate STK11/LKB1 function by controlling its subcellular localization.
Subcellular Localization:
Cytoplasm.
Sequence:
MFGSAPQRPVAMTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKLVHVAGPGPTGPIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDSSLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNLLEGHRELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLSDSLSSGGVVTQPLLCVSGSSSHSAA
The following text describes a protein:
Function:
Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAEPGTGSGDPAFGPGASESGTRRLSDLRVIDLRAELKKRNLDTGGNKSVLMERLRKAFKEEGQEPEEVGISWGAVSKRAVKRNTKGSKMEEEGSEDNGLEEDSRYGQDGVVILQSSQDRDTMDTGVPDGMEAEDLSVPCLGKADTVNQILHAFDDSKEYVAAQLGQLPAQLLKHAVDEEVFKNTLEASVSDLKVTLADEEAPMEPENEKILDILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEEEDQEEEQEEEGDLALASSSKSESPSTRCQWSEADAPLAVVKRELADAPGGGGGTRHRRKRKRRRKHQAQAEALGTGGGAGMNCEPVGLEEPVEQSSTAAQLPEATSQELVRAPTAALSPEPQDSKEDVKKFAFDACNDVPAPPKESSASEGADQKMSSVKEEQDIKPVIKDEKGRASCSSGRNLWVSGLSSSTRAADLKSLFSKHGKVIGAKVVTNARSPGARCYGFVTMSTSDEATKCISHLHRTELHGRMISVEKAKNEPSEKKSSDRRACDQKEKVPGPDRPHPVKIKTEKTVIKKEEKLERKEEKGPEDIKKEKDQDELTPGAAGHSRVTKSGSRGMERTVVMDKSKGEPVISVKATSRSKDRSSKSQDRKSEGREKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLDAFQERREKARLQRERMQLQCQRQRLERERLERERLERERMRVERERRKEQQRIMREREELRRQQEQLRAEQERRALRRPYDLDARRDDGYWPEGKRAALEDRYRDFPRPDHRFHDFDHRDRGHYQEHVIDRRDGSRTRVEERDGQYYPDDQHSHGRLLEHHAWDSGDGWHGYSSDKKLNEGQGLPPPPRVSREWAEHSSQLEEQQVPVWHSAVDTNMTGHEHIRWRGAERGLAGGPGHGHVAAGRGGMAGQGSFAHGGHSQGYIVPSGRLEGGGMASQDQGGRVPNPHPHPHFTRRY
The following text describes a protein:
Function:
Defense against chitin-containing fungal pathogens.
Subcellular Localization:
Secreted.
Sequence:
MRLLVLGLFSVLCLKCVLSQNISSLISKNLFERILVHRNDAACGAKGFYTYEAFITATKTFAAFGTTGDTNTRNKEIAAFLAQTSHETTGGWATAPDGPYSWGYCYKQEQGSPGDYCASSQQWPCAPGKKYFGRGPIQISYNYNYGAAGSAIGVNLLNNPDLVANDAVVSFKTALWFWMTAQQPKPSAHDVITGRWSPSVADSAAGRVPGFGVITNIINGGMECNRGSNALMDNRIGFYRRYCQILGVDPGNNLDCANQRPFG
The following text describes a protein:
Function:
A acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MDTDSRLEREQFVSHLNGTTTIEILSLTSLMPISILFRQCIIALIGIKLNRSNQWSRFTLDVACLCLPFLLSCTIMYDYCYVLFVTMITIIVASILWRYQQPPRHSLSKKKIDFNNLNVSCQLKFISYYRIEVNICTAIAILAVDFKIFPRCLAKAETYGHGLMDIGVGCFVLAAAIVAPEARYSIYRNASAPFSSSLVKSLKSIMPLVVIGVGRLIATAGINYQLHVSEYGVHWNFFFTLAAIRLLASLIFIIIPISLSGLIGACIGVFYQVTLTNYNLKDVIISGFDGSGGRNGIIEANREGIFSCIGYLSLYLIGIEIGKQLLKPISSLTRWLKVLVILIIVDIVLWELTWFNAELFEPVSRRFANFSYVLWMVTFMAFNIFMYLLVELISTYFTMTGNFCEEMPLAGCSVCTPTLENRTCACLYAAIERNQLGYFLLANVMTGSVNLSMNTIRVDNILAAVILVGYIYAVSFIIVVLHVNKVTTKIW
The following text describes a protein:
Function:
Putative pheromone receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSSHKESPEIVYFTLFFFGILGNTFLLSLHAIMFITEHRKRLIRLIIINMAFAHILMILFRGIHLIINNWGWTSLLDDTIAKIFIFFIILTRGVSLCSTCLLGIFQALTISPRSLNIKTRAQNYILLCCVLSWIFNLLFNITLPLNMSSPRNSSEERWRIGHISFGLHAIIIKPLIYESLVNALLVGLMICSSGYMVFVLYRHNQQVQHIHNIRLSSRASPETRATKVILMTVITFVCFNSASSPFVIYVASTKETRHWALLFTVLLSLFYPIVSPFMLIIMDTQISQAFCFLLGFNKSFQKEYPC
The following text describes a protein:
Function:
Transcription factor required for correct cell fate determination and differentiation in diverse neuronal cell lineages where it plays a role in specifying the fate of daughter cells during cell divisions. Involved in sensory neuron production and function. Binds both alone and with mec-3 to the mec-3 promoter to initiate and maintain mec-3 expression which is required for sensory neuron differentiation. In addition, binds both alone and with mec-3 to the promoters of mec-4 and mec-7 which act to regulate sensory neuron function. Involved in determining the identity of the serotonergic NSM neurons and the cholinergic IL2 sensory and URA motor neurons. Promotes expression of the cfi-1 transcription factor in the URA and IL2 neurons which in turn activates normal URA and IL2 gene expression. Required to determine the identity of BDU sensory neurons in concert with transcription factor unc-86, regulating expression of a number of genes, including transcription factors ceh-14 and ahr-1, neuropeptides flp-10, nlp-1 and nlp-15, and tyramine receptor-encoding ser-2. Regulates expression of a number of genes in NSM neurons including bas-1, cat-1, dop-3, mgl-3, nlp-13, scd-2 and ptps-1. In the IL2 neurons, required for expression of cho-1, gcy-19, klp-6, lag-2, unc-5 and unc-17. Promotes expression of pkd-2 in the male-specific CEM head neurons. Required for dauer-specific branching of IL2Q neurons and nictation behavior. Controls both the timing and direction of axon outgrowth in HSN neurons. Plays a role in serotonin production by regulating expression of the tryptophan hydrolase tph-1 which catalyzes serotonin synthesis, in the AIM, NSM, HSN and RIH neurons. Involved in regulation of lin-11 expression in the AIZ interneurons, the major interneurons of the olfactory pathway, and is required for odortaxis behavior. Involved in neurite pruning between AIM neurons during larval development by regulating the expression of transcription factor mbr-1. Required for correct localization of unc-40.
Subcellular Localization:
Nucleus.
Sequence:
MQNTAPVPTTTTASKMQPFNNSLFGSFDDPILNARAAQVALADIDVKNVPQLTNPLMRPHDMFSYSNYFSGIHDTSAATNIYQGLPSSSEPFDASVVVPTSSDDQMTPLQQVMAMQQSYGAPPPFQYNMTHPFSTTSIASSNNLARYPIAPPTSDMDTDPRQLETFAEHFKQRRIKLGVTQADVGKALAHLKMPGVGSLSQSTICRFESLTLSHNNMVALKPILHSWLEKAEEAMKQKDTIGDINGILPNTDKKRKRTSIAAPEKRELEQFFKQQPRPSGERIASIADRLDLKKNVVRVWFCNQRQKQKRDFRSQFRARSAAAVMGPRVMPVLNGNNSNNNLKQGQTTYNGLPGFFD
The following text describes a protein:
Function:
Probable positive regulator of Notch signaling.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAGGVLPLRGLRALCRVLLFLSQFCILSGGEQSQALAQSIKDPGPTRTFTVVPRAAESTEIPPYVMKCPSNGLCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECTNSTSCMTVSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI
The following text describes a protein:
Function:
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
Subcellular Localization:
Cytoplasm.
Sequence:
MRKPLVGINMKNYINTRAQTSEWLEATIPLLGNFSDVDTFIFPSMGTLETTANLLAGTSFGFGPQNMAPEKSGPLTGEFSVESIIDLSANYVEIGHAERKNLFHEKTSEIAKKIQLALDEKITPVVCVGEGIRANDTNELKNALKKQIEALFDTIQVTQFKNVVLAYEPEWAIGKANSADTDYIESAHQALREIIRELGGDETLVRIIYGGSVSKENAAEIVRQKNVDGLFVGRFGHKPQNFADIVSIVSKTKG
The following text describes a protein:
Function:
Probable transporter of a GTP-driven Fe(2+) uptake system.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MGMFERKRSLPADGTPAGAVTRKVALVGNPNVGKSVLFNALTGAYVAVSNYPGTSVEVSRGSASFEGGSWEIIDTPGMYSILPITEEERVAREILLTERPDVVLHVLDARNLERMLVMTLQLVEAGLPVILVVNIMDEAERMGLEIDIPLLQEKLGIPVIGAATAKKRGLPEIRKAIASCDAAHHASFGYSRRLEGDIAEIAGLLSGEYTLSGKSLALLLLQRDEEIAALVAGKEGDRAGAIAEKVREKTFERRESFHLDLSLERKGIVKGLLAGVLRTPEKRRVTAGERLSSWAVHPLTGVPLLLAVLYYGLYQFVGVFGAGTLVDFLEGTLFEEYFNPWIIGVVNGIVPWEIIRELIVGEYGIITLGLRYAVGIILPIVATFFLFFSVLEDSGYFPRLALLVDRIFKKFGLTGRAVIPMVLGFGCDTMATMVTRTLETTRERIIATVLLTLAIPCSAQLGVIMALLSQAPGALLVWSVCLLLIFLVVGFLSAKVMPGETPMFYMELPPMRLPQLSNVMTKTYTRMQWYFMEILPLFILASVLLWLGKITNFFDKLVNWMEPVMAFIGLPRDAAVAFIFGFFRRDYGAAGLYDLQTKGLMDPRQLVVAAVTLTLFVPCVAQFLMMKKERGLKSATLIALFVSVVAVGSGWALNRFILFTGIL