lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MASIRRAPFAAVRDRPSKGQSLLGRPAQSSPSLLHGLRCLLGGLPARRGPWRRSFLRALLFAFLVGFFWGLFSFPDLDDAGSLAPPHGFFFDPVRSANATAAEEPVDPFSKLLIIVTPTYNRASQGYHLNRLAHTLKLVPPPLLWIVVETKTATLETADILMRSGVMYRHLVCRKNTSVSLHRDVRQRHTALKHIRHHRLDGIVYFADDDNVYSLDLFERLRRIRRFGTWPVAMLSQSKNKAILEGPVCSGGRVIGWHTNEKGNNLRRFHVDMSGFAFNSTVLWNPKRWMYPKDAIELLDTVSEGFEDTGFIEHIVEDEHQMEGLPDDCSRIMNWRMHLEAKNRVYPRGWQTSKNLDAIIPLK
The following text describes a protein:
Function:
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein.
Sequence:
MEQYAVYFALVCAAAAVVYGLASAQWILGLPQGNERMRQIAAAVQEGAGAYMKRQYTIIAVVGVVMFIALFATLGMKTAVGFAIGAIFSGLTGFIGMFVSVRANIRTTEAAKSGIHKALNVAFKGGAITGMLVVGLGLLGVAGYYLVLQQLMPGAPVKDIVSQLVGLGFGGSLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETYAVTLIAAMLLGAIAFNNFSGAVTYPLILGGISIIASIIGTFFVKLGASQKIMPALYKGLIASGVIACIAFYFVTVQMFPEGNPTGYSATNIFISAIVGLVVTGAIFWITEYYTATEYAPVKHIAQASTTGHATNIIAGLGVSMKSTAMPIIVIAAGIIVAFQCAGVYGIAIAAVSMLSLTGIVVAMDAYGPITDNAGGIAEMAELDDSVRAVTDPLDAVGNTTKAVTKGYAIGSAGLAAVILFTSYVDELKLAGQNIEFSLADPYIIVGLFLGGMLPYYFAALCMEAVGKAGGSVVEEVRRQFREIKGIMEGTGKPDYAACVDIVTKSALKEMVIPGIIPIAAPVIIGFTLGPKALGGVIVGTIVTGIFVAISMTTGGGAWDNAKKYIEDGYHGGKGGEAHKAAVTGDTVGDPYKDTAGPAVNPMIKIINIVSLLIVPLLAKMG
The following text describes a protein:
Function:
Member of the two-component regulatory system SrrA/SrrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels as well as biofilm formation. Also plays an essential role in host-derived nitric oxide resistance by regulating hmp/flavohemoglobin, an enzyme that detoxifies nitric oxide by converting it to nitrate (By similarity). Functions as a transcription regulator by direct binding to promoter regions of target genes (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMDGIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRTQSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVFDREQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVKSNDEPAK
The following text describes a protein:
Function:
Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development.
Subcellular Localization:
Nucleus.
Sequence:
MELDDFDPEDKEILSWDINDMKLPQNVKKTDWFQEWPDSYVKHIYSSDDRSAQRHLSSWAMRNTNNHNSRILKKSCLGVVVCSRDCSTEEGRKIYLRPAICDKARQKQQRKSCPNCNGPLKLIPCRGHGGFPVTNFWRHDGRFIFFQSKGEHDHPRPETKLEAEARRAMKKVHMASASSSLRMKGRPEMKGLPGEIPSQGSLPLTWSFQEGVQLPSGYSTPLIANAPQQNSLNDCLSFPKSYDLGGTTELEDPTSTLDPTKLYERYKFSSSKVYSAEDQFQPPVPGVYGDYDEAQTWNKNAVLGRSPTDDTYYPPYPLPVASWPCDYLPSQSSLEHSPQQVPLEPPAAQPGHHPLWTNPGGEPYEEKVPVDFSSYVPSVTYHSPQQDPFLLAYGSHPQQQYALPGKSNRWDFDEEMACMGLDHFNNEMLLNLCSLK
The following text describes a protein:
Function:
Seems to function only as a co-chaperone, along with cpn60, and in certain cases is essential for the discharge of biologically active proteins from cpn60.
Sequence:
MGSEPEQMAVLEMGQYRSNKLSVMGRPFLIVSGPACEEPSGHKTLNPRAEGDRLVVRRRSASWKLRAFWLAAQEEEEKAAMAKRLLPSLNRVLVEKLVQPKKTAGGILLPETSKQLNAAKVVAVGPGERDREGKLIPVALKEGDTVLLPEYGGTEVKLAADKEYLLFREPDILGTLVD
The following text describes a protein:
Function:
Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.
Sequence:
MSIGWVTRTVVSDSAIAQYKPQDATTNPSLILAASKKPEYAKLIDTAVAYGKGVDGDLEKKTDATLDRLLVEFGKEILKVVPGKVSTEVDARFSFDTKATINKALRIIDLYKSEGIDKSRILIKIASTWEGIQAARILQRDHGINCNLTLLFSKSQAVACAEAGVESVKAIFDYYKKFGYKTIVMGASFRNIGEITELAGCDYLTISPNLLEELKNSTEAVPKKLVAENASSLDIEKLTYIDDEPEFRFAFNEDAMAVEKLREGISKFAADAVTLKDILKAKLQ
The following text describes a protein:
Function:
Pectin methylesterase (PME) inhibitor that targets PME from seeds and modulates PME activity and pectin methylesterification during seed germination.
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MATMLINHMLFLTSLLIVVFPVANAIPARDIDKLCKETTDVPFCLKYLGTDPRIPAARDLTDVLLIAITQSKMQVDDATTHIDRVRRKFNGPHGRRRIEVCKTNYGIASARFHTAWELGLQKSFWDVEKLARIGTNAVIDCENVWRRDGPIQTSPLTFYNMNVFKLSGIILLIFNKLVT
The following text describes a protein:
Function:
Acts as an osmosensitive calcium-permeable cation channel. Specifically conducts cations including Ca(2+), K(+) and Na(+) in vitro. Inactivation or closure of the channel is calcium-dependent. Mechanosensitive ion channel that converts mechanical stimuli into a flow of ions: activated in response to membrane stretch and poke.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MATLQDIGVSAGINILSAFVFFIIFAVLRLQPFNDRVYFSKWYLKGLRSSPARGGAFAQRFVNLDFRSYMKFLNWMPEALKMPEPELIDHAGLDSVVYLRIYWLGLKIFTPIAVLAWAVLVPVNWTNNTLEMAKQLRNVTSSDIDKLSVSNIPEYSMRFWTHIVMAYAFTIWTCYVLMKEYETIANMRLQFVASEARRPDQFTVLVRNVPPDADESVSELVEHFFLVNHPDHYLTHQVVCNANKLADLVKKKKKLQNWLDYYQLKYARNNSQRIMVKLGFLGLWGQKVDAIEHYIAEIDKISKEISKEREEVVNDPKAIMPAAFVSFKTRWAAAVCAQTQQTRNPTQWLTEWAPEPRDVFWSNLAIPYVSLTVRRLIMHVAFFFLTFFFIVPIAFVQSLATIEGIVKAAPFLKFIVDDKFMKSVIQGFLPGIALKLFLAFLPSILMIMSKFEGFTSISSLERRAAFRYYIFNLVNVFLASVIAGAAFEQLNSFLNQSANQIPKTIGVAIPMKATFFITYIMVDGWAGVAGEILMLKPLIMFHLKNAFLVKTDKDREEAMDPGSIGFNTGEPRIQLYFLLGLVYAPVTPMLLPFILVFFALAYIVYRHQIINVYNQEYESAAAFWPDVHGRVIAALVISQLLLMGLLGTKHAALAAPFLIALPVLTIGFHHFCKGRYEPAFIRYPLQEAMMKDTLETAREPNLNLKGYLQNAYVHPVFKGDEDDYDIDDKLGKFEDEAIIVPTKRQSRRNTPAPSIISGDDSPSLPFSGKLV
The following text describes a protein:
Function:
Cationic peptide that possesses multiple functions. It acts as a cell-penetrating peptide (CPP), and as a potent voltage-gated potassium channel (Kv) inhibitor. It exhibits antimicrobial activities, hind limb paralysis, and severe muscle necrosis by a non-enzymatic mechanism.
Subcellular Localization:
Secreted.
Sequence:
YKRCHKKGGHCFPKTVICLPPSSDFGKMDCRWKWKCCKKGSVNNA
The following text describes a protein:
Function:
Binds RNA and DNA sequences non-specifically. May be involved in tolerance to cold stress.
Subcellular Localization:
Nucleus.
Sequence:
MAAKEGSRIFVGGLSPEVTDRDLERAFSRFGDILDCQIMLERDTGRSRGFGFITFADRRAMDESIREMHGRDFGDRVISVNRAEPKLGRDDGESHGSRGGRDSGYSIAGKGSFGGGGGGGGRVGEDECFKCGRVGHWARDCPSAGGGRGGPVGGFSSRASAYGGSDGRVDRYADRDRYVDRERYIDDRYDGAARYGARDRFDSREAYIPRDRYASDRYAAPADRFAGGDRYSRGSDRYPPGSYDKARSFERDIAPSAGSDRYGGGRAGGPIRGGGEEGRGFRSRAGAPYERPSRSGGGGAYPSSSTFDRY
The following text describes a protein:
Function:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Septum.
Sequence:
MSRSNQEALADFVADAPPGELNQVVEAISTVVDGNSSILSKLETDVHNKILDQCMVVSLGKSKSLVSKYNQLSKDTFYDSQSGQKFEFDFDTKKATPSGSHGSDSPIQGALDKYFSAHFPSEGAAGVFPQDDGSIALVLVDGKYNPANYWNGKWRSVYIFESGSLSGTIDVDVHYYEDGNVRLKSSEKVDLGSVSESDIVDAISKAEQQFQEKLNKSFNGLNEDSFKALRRQLPVTRSKINWGKSISNYRLGKDINVGGGRE
The following text describes a protein:
Function:
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
Subcellular Localization:
Mitochondrion.
Sequence:
MLFLLAYALVFGTSLLLAFRLFSLSGSVQTSTCHSNGTLFHALDNKVTVGGRTRGASSVVTDGPQAEMLRFLGETCCTLPARGKDLRVLAGPKQFFSELLRQISAAQHRIVLSALYIGDGPLARQLVTALRNRVSKARSDKKALDVCILLDYNRMHVRQNLKTVAELLNLQSEAASPGADSAVNVRLFLFQSPCRWNWLVAPFGRAREALGVQHTKIFCFDNCQTILTGANLSDDYFDTRVDRYLAVHDNPHVAAWFSGLVDALCALSYPVGIHKECNTNAGSATVAGCGDTKKWGQNANSSSGEFVVHAGSNLTIFPNMAGVDPSTQWYEFCEVAERRLRDFAHSSGAVAAEAWQVEQHPEMEDEATGHYDTLLFPTMQCARANIFHDSFIVQMLLRMAPRSTHIYLASPYLNMYGHFVDELLASSSPYDFITASVSTNGWYGSKGFARYIPYFYLQLQRAFRYLMKEYKCAHRIRLHEFSAEGKTYHAKGLWFMKDQKQGGAPVGRVGISSACAGGANNNDVVNCEETWDHVGEPYLVSYGSTNYGSRSVHRDVEVEVFLYTTNEGLRGALRQDLISLLQESTSVSDERFVGNGEGRFQPLVSLMAQMGQDLL
The following text describes a protein:
Function:
Involved in the regulatory network to control embryonic patterning and morphogenesis. Implicated in negatively regulating vab-7 expression at the anterior of embryos.
Subcellular Localization:
Nucleus.
Sequence:
MNPSTQIVVKMSNEELWKERYPNMEMISNSKRITPIFPEIKFKISGLEENSRYVLVLSLEKMDNIRYGINENKEWAPSSARKPKPHHNMKFFFHPEGTKLGKELMAETVEFTSVRITTSEKLSEKENVFYVHTMHKYVPVLTIRNLTTGEIASNIFKMEIAQFFPVSIYQQASMGRWKSDLNKHSTFGNRSEGGIKRKTSDAAGQLPSKRSSKKPVKKDVVDNSEVTLEVKTSQYLVNQNESNLTEYIPSSPLYSSQNQYQYPFHPYSPFDSSIPYPYSPMDYSYYFNPTFQSFSPENVYFDENRNPH
The following text describes a protein:
Function:
Probable S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA. Also regulates mitochondrial DNA copy number. Stimulates transcription independently of the methyltransferase activity.
Subcellular Localization:
Mitochondrion.
Sequence:
MLPLRCSWSFARANYSTKKELVTRYSGDFPEKLLNRKQKVPTHMYIANSEAAARINQYLEPHFQSSGCDTVMELNSGAGYFTRHLLDRESQFRRIILLESMDHFMPKIQELHTLYPERVKVRQGDFVNLWKLVYMDKMDGGSRVADLLSDVPQKAFTDDINMLVFGAVGSYPFFKHLINSLIFQTSLFNLGRCEMILAMPPPIYIHLTCNNEIGYLIYRSTSVLFQILFEHKFIAKVPREDFLPQQMAYSPTKSSKLGKVQSINPEYLYLVKFTPRRNLHELCQSQDLPALWFFIKQNYVSRRNRIIPNLEKWVPGCGPRLIINPKSSESVTPIYPDELPKKLPQYSCQSTTMSTRNYYPGINIYTQFGDLLPSQILTLFSQFRQWPEYGESSFLASLENALLKLETANDEPNLEDGVTLPEEDDAEADEIIEEESPVPATTPVKRRRKASS
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MSYSVNISVEAPIENQIQEITYDGTEIYQPPLTLSESLTKYAQKIDFSKTSDIDFKKEPGEAIEDNKSDSDSKDAFQSSLWPWDSARNKLRNAFQEVCVLADVLAIAKDKRYMVLDPVQQEPIETKPMVQIYARKKALAGAASVLLTGAERLKTSQNEAARNRTVPDFHIELLRLRQNWRLKKVSNTIIGDLSYRTAGSKYTQTGTFEVTKAEDDDKTNSPPSSPIPGGATTAKTNSALRVSIPSELQGVAYIEVLCQKDQEDLCSVNVNLLGSGPPASNPDMHWQQKLEAAQNVLFCKELFNQLAKEAVQLQAPIPHMVVGNQIMATVFPGIQLIIGLCHSTVGDKKQQNNNSSKTDHDHVLEHSLHQLLREVHHKNTHHPFPHPATGPLGPSKKRMLAGPMAADRYELLEMTKSETLLEQIIKQAQHFFMRLRTEYVLDTIAKEVKDPLISSHWNTLNSPTQSCVKINISTHGYDALCRTPLVIHVGEKSLKCICRDGKVMHMSYEPQELRDLIFCHINQHQILAVQALAKTMGWQFLANSNHLGTGAVEPLGNASSCLLASPTGDRIIAVRCEPQTGIQVCVAHSPRSDFFPSRLVTERKWEHLGGQFRDVRLEKMEGRNFLHKMELLMASLTSSS
The following text describes a protein:
Function:
Plays a role in the inhibition of host NF-kappa-B activation. Interacts with host BTRC and thereby diminishes ubiquitination of NF-kappa-B inhibitor alpha/NFKBIA. This stabilizes NFKBIA and its interaction with NF-kappaB, so retaining p65/RELA in the cytoplasm and preventing NF-kappa-B-dependent gene expression.
Subcellular Localization:
Host cytoplasm. Host nucleus.
Sequence:
MDEAYYSGNLESVLGYVSDMHTELASISQLVIAKIETIDNDILNKDIVNFIMCRSNLDNPFISFLDTVYTIIDQENYQTELINSLDDNEIIDCIVNKFMSFYKDNLENIVDAIITLKYIMNNPDFKTTYAEVLGSRIADIDIKQVIRENILQLSNDIRERYL
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MAQDLTEKELLKMELEQLKKEVKNERALISKTGKEIKEFVEAQAAEDPLLKGVPEDKNPFKEKGGCSVS
The following text describes a protein:
Function:
Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma-carboxyl group of the C-terminal glutamate residue in LysW.
Sequence:
MPRWEEKNLIEEGKKLGYQVATIYSKDFVLFSNDFTIDNDTDLFIQRNVSHNRALITSFLVEQVGYPVINDHTTLIRCENKIFTTYILARHNIPTPKTFIAFDKTNAIEYSKKLGYPVVIKPVEGSWGRMVAKADNLDVLYSYLEYQEFSTQKYKDIYYIQEFVNKPNRDIRIFVIGDETPVGIYRVNENNWRTNTALGAKAYPLKIDEELRELALKVKDIIGGFFLGIDIFEDKDRGYLVDEVNGVPEYKNTVRVNNFNVSKFLLEKAAEWVKK
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MSFARPARCLFCSFSRAAANSPRVPRRQFQLSATQFTDKPSKKPVENGVNLKQLSQEMKPDDFKPYTEEEKAYLKKHYTPEQLAAIEAGEAAIDPKDMAEQFRIRKDPMKLTYLDDFSVIEPGVDKHVRAPESNSDYNATLKTEDDFVDDFAKFIAEMPEDASISDWVRFAETNRMTIGKEENELNPNSSLVPDLFQPGETLDGPSKKPHKYYDARRSNIAKKDEEPSEALKVLMKNTGYSLSDISSLRTKALVVKQVTNQTRLGKVNSTYILTVAGNGNGLLGIGEGKSQEATDARVQSLYRAIRNMKPVPRYENRTIFGDVKGKVGAVELKLMTRPPGNFFNTTFPLSEANKANLGFGLRCQSLIYEMCRAAGISDIAARVERARNPMNTVKAAYEALMSQRDPEEIARARGKKLVDVRKVYYSGREDRPRQLQY
The following text describes a protein:
Function:
Protein-lysine methyltransferase.
Sequence:
MILFNLLETQLTRVHSFQEMIKKASVYRHPLANHLMDPEVQKESREDGDDRTVVAEIMRRCFVPAFVTTIPWEGFHFAGHEIRINEATDCYGAVVWPSALVLCYFLETNVKQYNLVDKNVIEIGAGTGLVSIVASLLGAHVTATDLPELLGNLQYNISRNTKTKAKHLPQVKELSWGVALDKNFPRASINFDYILAADVVYAHPFLEELLVTFDHLCKETTVILWVMKFRLEKENKFVDRFEQLFDLEEISSFPSLNIKLYKAMKKNQKSACYPQRRMWKAKPISGRLLL
The following text describes a protein:
Function:
O-methyltransferase involved in the biosynthesis of the permethylated L-rhamnose moiety of elloramycin, an antitumor polyketide. Mediates the methylation of the hydroxy groups at the 2'-position after the sugar moiety has been attached to the aglycon.
Sequence:
MDSPQVARTLVDSAGGTAAHTREAIRQIGVPETAAFLADELAGRTETVTIRHAAEVQFVFDDRYAPDAADPVPWTFRVGPEGVTHRAGALPDPGAVVTQDLTELARSLYGPAADRSDATRTVWWRDHDDPRVYFDPPPVFPAVERLLAAADGRDVPGLAGLALRHGSDKWGIHTYTAAYEQHFAPFRDRAVTVVEIGVGGYDDPAAGGGSLRMWKRYFRRGLVYGVDIADKSRHREPRVHTVVADQSDPASLRDLADAIGPIDIVIDDGSHISAHVVTAFSTLFPRLNPGGLYVVEDLQTSYWPAFQGAYDDDTRTSVGFLKRLVDGLHHAEYPSRAGRPAQPTDRTVGSLHFHPNLAFVEKRANSGHGGISRLREAT
The following text describes a protein:
Function:
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as secondary nitrogen source when primary sources are limiting.
Sequence:
MVLKTFKVDGISPIKAETLTPESFSKYGGVISADHQLEKVQSSEANYGTAIKIHKVAPIVNNYSNCPSGKEATANWNIFRCKAPKHLINHGSLNSVYTSKVLERHPFSTQTFLPLGQDLHKVSYLVIVAKTDESTEEKLPDPTSIRAFVCKGNQSVTYGIGTWHAPMVVIDEKVPHIDFAVFIHENGVADEDVQECYFEPGYSIVYNQIEAKL
The following text describes a protein:
Function:
NAD-dependent protein-lysine deacylase that decrotonylates the PDC (pyruvate dehydrogenase complex) subunit LAT1 at 'Lys-148' to inhibit PDC activity and consequently ATP production. Also decrotonylates histone H3 crotonylated at 'Lys-18' (H3K18cr), to repress the expression of genes involved in aerobic respiration. May also act as a NAD-dependent deacetylase (By similarity). Does not mediate desuccinylation, demalonylation, or deglutarylation of LAT1.
Subcellular Localization:
Mitochondrion. Cytoplasm, cytosol. Nucleus. Chromosome.
Sequence:
MRLLRPTPRLSSIFSSKTATSNLRFFTAMAPHNDVGAFHEALRSSKRILALCGAGLSASSGLPTFRGAGGLWRNHDATSLATLSAFKNDPGLVWLFYNYRRHMCLRAEPNPAHYALAALAEKNKDFLCLTQNVDNLSQQAGHPQDQLRTLHGSLFDIKCTNCDWIQRGNYDDPFCPALAPASVDVEPGKPFPLLDASLPLDPISPDDIPKCPQCKIGFQRPGVVWFGENLDEVMMMGITNWLLEDKVDLMLVIGTSAQVYPAAGYIDKAKRKGARIAVINPEAENEEEMYKVKPGDFAFGKDAAEYLPLLLEPVIGKLETDKKERS
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MELILFLITALIAIIGAVAMLVSRNAVHSALFLLLNFAAIAVLFLLLNAPFLFAIQLTVYAGAIMVLFLFVVMLLGAEKVEDTPDQIPWQQPLALLLGLALLVISVVVGLGGATNPPPESEALAQFSDPQTLGALLFTDYLLPFEVTGFILLIAVIGVVVLNQRGRKI
The following text describes a protein:
Function:
Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport.
Sequence:
MASAVPYNPDGFDNPFAESENGHGVLNNHDDDKGNVGGAGEADETSNAVYEEEPADDNKPFVGEDGDDDAHDVGSVSVHGGFGEQGAHDTAESASDQVVSGDNAADSAAVDGAAPAPADGATDADAISATKPADGETKKPVKRFLKIRVMAIEPGKTIIYRLEGTTNFPKYRTSHYRDIRRTHGEFVALFEHLNGANAECFVPAVPALPSGSIGNSNNTHAAEQARKVMQTWLDRVCGDPILCRDDEMRFFVEADFGYSPNVKRRPPATGLKRKAMKQWAPPLDDNAELRDFRPVVKALYNTGSDTVSKYERQCKIERQLALGLAELGHKTIACGDVLNPGAAALRSRDLGPVFAAFGQALVSVSDIAYARAAVQIASFVDPLDLVSQTGYVAKEQLTNRHLLMRELETLQTNAKNKHIAAERIKISGQHNPHKVDEAIALYEEATRAETRLSNRLKRISDALCIGKTKLTKNVEEDLTQAVREVTQRVIECERRTLAVWENIRGDVRAADGARGGLSRLGRKRVGASQAQTRSQGPGGDAWSGDRKVRAEDQDQEVDEGDLDESRVDAKMAASLLGGSTF
The following text describes a protein:
Function:
GTPase that plays an essential role in the late steps of ribosome biogenesis.
Sequence:
MSNRVVIIGRPNVGKSTLFNRIIGKRYAIVEDYPGVTRDKIEAKAEWAGKEFIIVDTGGLVPETKDELIREVKKVVEQEIPKADVILFVVDGKEGLNPLDQEIAKYLYPYADKVLLVVNKIDNLRQEKNVAEFYTLGFEKIFPISAQHGKGVGELLDEVVKYLKEEKVETVEEGIKVAFIGRPNVGKSSLVNAILKDERVIVSPIAGTTRDAIEIPFRWKDKNFILIDTAGVRRPSNVEYGIEFYSVGRSLKAIDLADVCCLVIDASEGPTRQDKRLGGLIERRYKGCVIVANKMDISPWSEEELEGIIRKELFFLDFAPIVFTVATKGKGVEELLNWIDVVYKDYTKQHKTSFVNRAVHKILSEKPPPRYRGKEVKVYYAFQESTKPPTIVLITNYPDAWKENYKRFFIKKLREYLNIKYAPIKLVIKGRED
The following text describes a protein:
Function:
Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites. Required for activity of RRP6 in 7S pre-rRNA processing. Also has a role in 3'-processing of U4 and U5 small nuclear RNAs (snRNAs). Acts as a mRNA export factor. Mediates mRNA degradation upon UV irradiation. Maintains genome integrity where it is involved in both non-homologous end joining (NHEJ) and homologous recombination pathway repair of double strand DNA breaks. During NHEJ, required for joining 3'-overhanging ends. Also involved in telomere length regulation and maintenance.
Subcellular Localization:
Nucleus.
Sequence:
MEDIEKIKPYVRSFSKALDELKPEIEKLTSKSLDEQLLLLSDERAKLELINRYAYVLSSLMFANMKVLGVKDMSPILGELKRVKSYMDKAKQYDNRITKSNEKSQAEQEKAKNIISNVLDGNKNQFEPSISRSNFQGKHTKFENDELAESTTTKIIDSTDHIRKASSKKSKRLDKVGKKKGGKK
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MERDFLGLGSKNSPITVKEETSESSRDSAPSRGMKWSFPNKASATSSPQFLTFRPSQENRHRNLGNYHLPHSGSFMPSSVADVYDSSYRSTPYSSVQGVRMFPSSKQHEEAISVSMSRPSLQSHYASGGTSFINNSVNSQPLVGVPIMAPPVSVLPPPGSIVGTTDIRCSSKPSGSSPAQLTIFYAGSVCVYNDISPEKAKAIMLLAGNGSPMPQVFSPPQTHQQVVHHARASVDSSAMPPSFMPTVSYLSPEAGSSSNGFGAAKAARDFTTTYLSNQTNASNINSSVAASCSANVPQTVALPQARKASIARFLEKRKERVTSLSPYCLDKKSSTDCRTPMSECISSSLSSAT
The following text describes a protein:
Function:
Mesodermal transcription factor that plays a key role in somitogenesis and somitogenesis and limb muscle differentiation. Required during limb development for normal appendicular muscle formation and for the normal regulation of myogenic genes. Also acts as a negative regulator of angiogenesis.
Subcellular Localization:
Nucleus. Nucleus speckle.
Domain:
The polyhistidine repeat may act as a targeting signal to nuclear speckles.
Sequence:
MEHTLFGCLRSPHATSQGLHPFAQSSLALHGRSDHMSYPDLSSSSSSCILTGYPNEESMFGSQHHRGHHHHHHHHHQQQQHQTLQSNWHIPQMSSPPASTRHSLCLQQDSGPPDLSGSPSILCSNTSSLGTNNSTGAACVTGDYGRQSLSPAEAEKRTGKRKSDSSDSQEGSYKSDVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIRSNSLQHTADSLTNDDSHDSSQSSEHAHL
The following text describes a protein:
Function:
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MADEGDLLVVLFDLVLLRPDNPSADSLDVTPAEILSQLLAFANAYTMLSSHNRLAVFAGQHDFSHLVHLGLGEDASNTEVFPAGALHTRLTDLVTQCAAAAAAGGAGAGAAANAGQGAGPGFALSGALSRALCLVHRLQQQQAAAGGRPRGRPRVLALLGCGDTAAQYIPVMNAIFSAQRAQVVLDAVVVAPQDSSFMQQAAHLTGGLYFRPHRGRGLLGVLLNHFVCDTATRKQLDEAQALGVDFRASCFCHKYVIETGYVCSVCLSIFCQPSRSCTTCGTAFGAGGKAVGAGGGGGGAGAVGGGS
The following text describes a protein:
Function:
Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in cystathionine, djenkolate, and S-methylcysteine transport.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQFDFPFIVSAMKEMVKTIPLTLMMAVLPIVFGFLVALGNIIVRIFRIKGLVACSRFYVSFFRSTPAILHIMLIYLGIPPVADQVSSFFHLGWSANEIPVSMFVIMALSLTAGAYLTEIIRSGILAMDTGQVEAAYSIGLTYSQTFRRVILPQALKVSIPNFTNLGIGFLHTTSIAAIVAVPEITGTATIVASDNYAFLEAFIGAAIIYWVLTLILESANGVLERKAARFQGGTL
The following text describes a protein:
Function:
Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids. Contributes probably to abscisic acid synthesis for the induction of seed dormancy.
Subcellular Localization:
Plastid, chloroplast stroma. Note=Partially bound to the thylakoid.
Sequence:
MQHSLRSDLLPTKTSPRSHLLPQPKNANISRRILINPFKIPTLPDLTSPVPSPVKLKPTYPNLNLLQKLAATMLDKIESSIVIPMEQNRPLPKPTDPAVQLSGNFAPVNECPVQNGLEVVGQIPSCLKGVYIRNGANPMFPPLAGHHLFDGDGMIHAVSIGFDNQVSYSCRYTKTNRLVQETALGRSVFPKPIGELHGHSGLARLALFTARAGIGLVDGTRGMGVANAGVVFFNGRLLAMSEDDLPYQVKIDGQGDLETIGRFGFDDQIDSSVIAHPKVDATTGDLHTLSYNVLKKPHLRYLKFNTCGKKTRDVEITLPEPTMIHDFAITENFVVIPDQQMVFKLSEMIRGGSPVIYVKEKMARFGVLSKQDLTGSDINWVDVPDCFCFHLWNAWEERTEEGDPVIVVIGSCMSPPDTIFSESGEPTRVELSEIRLNMRTKESNRKVIVTGVNLEAGHINRSYVGRKSQFVYIAIADPWPKCSGIAKVDIQNGTVSEFNYGPSRFGGEPCFVPEGEGEEDKGYVMGFVRDEEKDESEFVVVDATDMKQVAAVRLPERVPYGFHGTFVSENQLKEQVF
The following text describes a protein:
Function:
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
Subcellular Localization:
Cytoplasm. Endosome.
Sequence:
MNRLTWYTPGESTEELLCQAGHVGIYEGDLKQTQFEQGTVSLTMQRIIWADSSDPDRRLVLHHSLVISMEKHHKSMFSKGGKVVVRLEKPKPGSVGPVNSSQYDTIRLVFRHGGEDDFFKKYEDAVRRKTWQRSSSGSSSSGSRASSNLRSVGISGIERRLAENHQKTHETITQAFDDMSKLMETAREMVAISKSISEKVRSRKGEISEDETVQFKSYLLSLGVSDPVTKSTFVGSDSEYFQSLAKEITDVLYQHIKENGGMCALPEVYCRINRARGMELLSPEDVMNACGALSRINSPLELHRFPSGVLVVQLKSASMESTVAQTLEFVSKLERASANELAESLGITVILARERLLAAEESGQICRDDSIEGLLFYPNRFMD