lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Mediates phase variation of the LPS epitopes. Phase variation of H.influenza LPS epitopes expressed by LicA is determined by a translational switch (By similarity).
Miscellaneous:
MISCELLANEOUS: Lipopolysaccharide (LPS) is a glycolipid that is a necessary component and antigenic determinant of the outer membrane and has been shown to be an important factor in the host-parasite interaction in a number of Gram-negative species; MISCELLANEOUS: H.influenzae is able to display an extensive repertoire of different surface configurations through variability of its LPS oligosaccharide.
Sequence:
MTNQNVLLNISGVKFVLRIPNAVNLSLINREYEAFNNAQAYRAGLNVETPVLDAKSGVKLTRYLENSNTLSQIQLNEQSCLSQVVNNLYRLHNSEFVFRNVFSVFDEFRQYFSLLENKSAFYQADSRMDKLSAVFWQFEEINKEVILRPCHNDLVPENMLLQDDRLFFIDWEYSGLNDPLFDIATIIEEAHLSKEAADFLLETYCNQTNKYHKTEFQIAHKRLKIHRFCQNVLWFLWTKVKEEHGENFGDYALKRLDAAFKLLEELP
The following text describes a protein:
Function:
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.
Sequence:
MSMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFEAVAGLTHVLETLLDELRSNKRQLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVHTRLNAVLAGEAPAAVVVAKPKEEEPEAWHIGFTPAPSLFMSGNDPLRIIRELEHLGPLQIAARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPPSLAVEAAGTAAVAVATTAAAEPAAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGELVITQAMLKQVSTGLDPAHAEQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVRDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNSIDHGLEMPDARRASGKDETGTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDSQVWDLIFAPGFSTADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAGETLILPLSYVLEALQPAPEDVRSMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESLVVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSGATILGDGRVSLIVDIGGLVRSLKVPQAA
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Miscellaneous:
MISCELLANEOUS: Present with 1010 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTYEQLYKEFHSSKSFQPFIHLDTQPKFAICGLIVTLAVLSSALFAVGSKSSYIKKLFFYTILSVIGSLFAGLTTVFASNSFGVYV
The following text describes a protein:
Function:
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MASPLVAGLSVAVAALAGKYGIEAYQAFKLRPATPRLRKFYEGGFQPVMTRREAALILGVRESVAQDKIKEAHRRVMTANHPDAGGSDYLAAKINEAKDHLLGQTRGSGSAF
The following text describes a protein:
Function:
Receptor for basic fibroblast growth factor.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MEAFMSQVKPAGSTVTYKCPADGYPKPEIVWTKDGGPIKRHLGSAKLQKWSLELEEATTYDSGNYTCTVSNSHGSVSFTFKLLIQERFPHKPLIMEMHNSTVSIGGTVSFECRVISDLTPYVQWYRHFTDDNGSFVNDTTGTPIGNALQVNNDHQVLRLENVTKEDAGWYTCMAGNSLGMSYRSAWLTVEEESPSIDHLLEGGLHHLQDQKVVIILASVLGSIVLAFVVLFAIAFRKRYSRQKRNKFMALETAHCIAPCTKKVIIEQRSAVNGVGGGIHEPLLFPVIKIEKHRSRLGTDIGSVSEYELPLDTRWEFPRQDLQLGKSLGEGAFGHVVQAQANGIIEKNSVSTVAVKMLKEGHTDTELMDLVSEMEMMKMIGTHVNILNLLGCCTQDGPLYVIVEFAPYGNLRDFLRQHRPSSGYERAIGQLGWKLGNTSYEHPIEFNSTGRMGQDTLTHKDLISFAYQVARGMDYLESKKCIHRDLAARNVLVSEDCVLKIADFGLARDVHMHEYYRKTTDGRLPVKWMAPEALFQRVYTSQSDVWSFGILLWEIMTLGGTPYPSVPNIERLFQLLRDGHRMEKPVSCSLEVYLLMRECWQYNPMERPTFSELVEDLERILKLTSNEEYLELGFESPETPPSSRENSDCRTQFVVSTV
The following text describes a protein:
Function:
Counteracts the host antiviral immune response when activated and phosphorylated, by preventing host IRF3 from entering the nucleus. Also inhibits the type I interferon production by inactivating the enzymatic activity of DNA sensor CGAS without affecting STING1. Participates in the transactivation of viral major immediate-early genes by the recruitment of host IFI16 to the promoters pf these genes.
Subcellular Localization:
Virion tegument. Host nucleus. Host cytoplasm. Note=As part of the incoming virion, pp65 is targeted to the nucleus immediately after infection. The newly synthesized pp65 is observed in the nucleus until some time after 48 hours postinfection. Thereafter, pp65 is probably exported and accumulates in the cytoplasm. Also found in dense bodies.
Sequence:
MESRGRRCPEMISVLGPISGHVLKAVFSRGDTPVLPHETRLLQTGIHVRVSQPSLILVSQYTPDSTPCHRGDNQLQVQHTYFTGSEVENVSVNVHNPTGRSICPSQEPMSIYVYALPLKMLNIPSINVHHYPSAAERKHRHLPVADAVIHASGKQMWQARLTVSGLAWTRQQNQWKEPDVYYTSAFVFPTKDVALRHVVCAHELVCSMENTRATKMQVIGDQYVKVYLESFCEDVPSGKLFMHVTLGSDVEEDLTMTRNPQPFMRPHERNGFTVLCPKNMIIKPGKISHIMLDVAFTSHEHFGLLCPKSIPGLSISGNLLMNGQQIFLEVQAIRETVELRQYDPVAALFFFDIDLLLQRGPQYSEHPTFTSQYRIQGKLEYRHTWDRHDEGAAQGDDDVWTSGSDSDEELVTTERKTPRVTGGGAMASASTSAGRKRKSASSATACTAGVMTRGRLKAESTVAPEEDTDEDSDNEIHNPAVFTWPPWQAGILARNLVPMVATVQGQNLKYQEFFWDANDIYRIFAELEGVWQPAAQPKRRRHRQDALPGPCIASTPKKHRG
The following text describes a protein:
Function:
Cysteine proteinases 1 and 2 are believed to participate in the breakdown of protein during differentiation of Dictyostelium as a response to starvation.
Subcellular Localization:
Lysosome.
Sequence:
MRLLVFLILLIFVNFSFANVRPNGRRFSESQYRTAFTEWTLKFNRQYSSSEFSNRYSIFKSNMDYVDNWNSKGDSQTVLGLNNFADITNEEYRKTYLGTRVNAHSYNGYDGREVLNVEDLQTNPKSIDWRTKNAVTPIKDQGQCGSCWSFSTTGSTEGAHALKTKKLVSLSEQNLVDCSGPEENFGCDGGLMNNAFDYIIKNKGIDTESSYPYTAETGSTCLFNKSDIGATIKGYVNITAGSEISLENGAQHGPVSVAIDASHNSFQLYTSGIYYEPKCSPTELDHGVLVVGYGVQGKDDEGPVLNRKQTIVIHKNEDNKVESSDDSSDSVRPKANNYWIVKNSWGTSWGIKGYILMSKDRKNNCGIASVSSYPLA
The following text describes a protein:
Function:
Converts protoheme IX and farnesyl diphosphate to heme O.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MLLSNVAVNRTVVHTQLVSGSRSALHALSRTSHSVPVTHTHQRRHIFSHKRRLSSSTLAIPFALSNTNSATTAPLQFLSNVSLCRVTPGTITTSAKATAPNLDKMSAEAATTAAQASASPVEDSFLKKAVSCQSETEREAVMAARAAKKALRETKETWWAPYVALTKPRLTVLVVLSAMSSYALTPEAVSLTNLLFLTVGTALCSGSANAINMGREPAYDSMMTRTRGRPVVRGAVTPNQAFTFAGITGTVGTAALYFGVNPTVAILGASNIALYGGLYTTLKRKHIINTWVGAVVGAIPPLMGWAASGGSLLHPGAWCLAGLLYAWQFPHFNALSYSIRDEYKKAGYVMTAWKNPGLNARVGLRYALLMFPLCVGLSYYNVTDWWFVLDSSVLNAWMAWWAFKFWQQENVNIALAAAGKQYSQNPFARKLFWGSVVHLPGVLLLAMIHKKGQWDWLFGPSEDEKKKTLSS
The following text describes a protein:
Function:
Involved in de novo DNA methylation. Controls asymmetric and CpNpG methylation. Required for FWA gene silencing but not for the maintenance of SUP gene silencing. Functionally redundant to CMT3 to maintain non-CpG methylation. Involved in RNA-directed DNA methylation.
Miscellaneous:
MISCELLANEOUS: DRM2 is expressed at much higher levels than DRM1, which is scarcely detected, suggesting that DRM2 is the predominant de novo methylase.
Subcellular Localization:
Nucleus.
Sequence:
MVMSHIFLISQIQEVEHGDSDDVNWNTDDDELAIDNFQFSPSPVHISATSPNSIQNRISDETVASFVEMGFSTQMIARAIEETAGANMEPMMILETLFNYSASTEASSSKSKVINHFIAMGFPEEHVIKAMQEHGDEDVGEITNALLTYAEVDKLRESEDMNININDDDDDNLYSLSSDDEEDELNNSSNEDRILQALIKMGYLREDAAIAIERCGEDASMEEVVDFICAAQMARQFDEIYAEPDKKELMNNNKKRRTYTETPRKPNTDQLISLPKEMIGFGVPNHPGLMMHRPVPIPDIARGPPFFYYENVAMTPKGVWAKISSHLYDIVPEFVDSKHFCAAARKRGYIHNLPIQNRFQIQPPQHNTIQEAFPLTKRWWPSWDGRTKLNCLLTCIASSRLTEKIREALERYDGETPLDVQKWVMYECKKWNLVWVGKNKLAPLDADEMEKLLGFPRDHTRGGGISTTDRYKSLGNSFQVDTVAYHLSVLKPLFPNGINVLSLFTGIGGGEVALHRLQIKMNVVVSVEISDANRNILRSFWEQTNQKGILREFKDVQKLDDNTIERLMDEYGGFDLVIGGSPCNNLAGGNRHHRVGLGGEHSSLFFDYCRILEAVRRKARHMRR
The following text describes a protein:
Function:
Catalyzes the selective oxidation of C1 hydroxyl moieties on mono- and disaccharides with concomitant reduction of molecular oxygen to hydrogen peroxide. This results in the formation of the corresponding lactones, which typically undergo spontaneous hydrolysis. Hexose oxidase is able to oxidize a variety of substrates including D-glucose, D-galactose, maltose, cellobiose, and lactose.
Sequence:
MATLPQKDPGYIVIDVNAGTPDKPDPRLPSMKQGFNRRWIGTNIDFVYVVYTPQGACTALDRAMEKCSPGTVRIVSGGHCYEDFVFDECVKAIINVTGLVESGYDDDRGYFVSSGDTNWGSFKTLFRDHGRVLPGGSCYSVGLGGHIVGGGDGILARLHGLPVDWLSGVEVVVKPVLTEDSVLKYVHKDSEGDDGDLFWAHTGGGGGNFGIITKYYFKDLPMSPRGVIASNLHFSWDGFTRDALQDLLTKYFKLARCDWKNTVGKFQIFHQAAEEFVMYLYTSYSNDAEREVAQDRHYHLEADIEQIYKTCEPTKALGGHAGWAPFPVRPRKRHTSKTSYIHDETMDYPFYALTETINGSGPNQRGKYKSAYMIKDFPDLQIDVIWKYLTEVPDGLTSAEMKDALLQVDMFGGEIHNVAWDATAVAQRKYIIKLQYQTYWQEEDKDAVNLKWIRDFYEEMYEPYGGVPDPNTQVESGKGVFEGCYFNYPDVDLNNWKNGKYGALELYFLGNLNRLIKAKKLWDPNEIFTNKQSIPTKSLKEYKQTK
The following text describes a protein:
Function:
Metal-independent, broad-range acid phosphatase. Involved, either directly or indirectly, in the bidirectional transport of sterols between the endoplasmic reticulum and the plasma membrane.
Miscellaneous:
MISCELLANEOUS: Present with 3170 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MCEENVHVSEDVAGSHGSFTNARPRLIVLIRHGESESNKNKEVNGYIPNHLISLTKTGQIQARQAGIDLLRVLNVDDHNLVEDLAKKYIKDESSRRTLPLKDYTRLSREKDTNIVFYTSPYRRARETLKGILDVIDEYNELNSGVRICEDMRYDPHGKQKHAFWPRGLNNTGGVYENNEDNICEGKPGKCYLQYRVKDEPRIREQDFGNFQKINSMQDVMKKRSTYGHFFFRFPHGESAADVYDRVASFQETLFRHFHDRQERRPRDVVVLVTHGIYSRVFLMKWFRWTYEEFESFTNVPNGSVMVMELDESINRYVLRTVLPKWTDCEGDLTT
The following text describes a protein:
Function:
Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MVLYKNKKKQIINYANSNWGQNEGVEFQETMLQCILEAVIVSKDAKQVLSLLHELKLFENFLWQRVNTEMSLNHINLTCMLLLYKSKYEYITWDLIDENRFQLFFEKVIEVSLSLNLSEVVYMIQFITLCFQFSNIEKLRKLVYQLTNISILNSLDNLDKVKYLLHDSSSLTKAFDSYKEKRPSIVEKFPLHNLLSRWIHSLLIKSISYAQTEKQEAKVTPLLAIINMSLVLLSAFPTRRFAHPVIEDSCFYTALRMSLYYDSNELFKKMTDDLNYVLKFPFDNTRGNEYEKEQKIRNDELVYYHLQLTLFSDFQKELGDLVFCTQTSLQQRQKLEEITSFLSFNSLKSLCSKCYLRTSFPEKYAIKVDFEFLKNVFINTYDRTRLVNDYDEIINFTLKDVLGERSVMDQENSLTNYFLLQNTAIQYLSISFFMRQQSKAYKKLLLRSLYAELLNFSEQYRRLSIKNATKNLTKDNFFSLNNFKVTSVAPPQIGQVLPQFVKCQMGLSRPGPFHSALRDLKNSIKSPFLCLIYISKDMEYKLLHGNALDPLEGVTDFTIATICNDDVGMFQSDMQSDSDNKSINVYLSPFYYHSLAGLGEYRPKQLKFNFALVLSPEANKYWLDLNILVSLLNRAKEFPKWFEDLFLGFGTPDICAFPNAGLNSIYARNLFNTVEQLQSVLPNCHVPSNLSTESLLIKFYTNQNKISADVTASDRHFLLPSNRLYTYNDKQLESILRGSQPGLTMVNGPTRCGKHVLVCKLLEVLQDTSPNDRTVVLSDSNFSMNTLFTLLEKARCFHQGHLLYLSDEGKDETLERYGTLSSWISKLPGLLREIGRLAASIQAPGSHDASPDTALYFRDAYIKRLWEKYLNTVDDKDSVDAYNRFPFHSYFGDKSKRPIETYNKDNFFDYATKLYGELEYMFQQLEEIRPFGLLRYYEDQELYALCQQSRIIGCTWTSLSTRLGTLKEKGFCFNNLIVMNSQNISESSITSILLSNCEPTGFDRLVLLGNQYLTSGNQDINNTSNGSLFKRLRYLKSRIIDLNTQYNVRESISSLCSSIYPLDIKTVDSSPNKRLDYGNSGFAHEVQFINVGAFKGSQETEPVSGYKQNLGEAEYAVALFQYMRMLGYPTNEIVICTLYESQVSLLNEIISVRCSHNSFFGQPAFVGTVEKLPSDKRVNFVIFTTVESKEASDHWNPKTFYKAFSACSYGLYVLCNRDLFRSTRGLEKLWNEIEKTPDKLLLTTGEIYPSSHKIGSSVETFEIENLLHLSNYVVEMTKKRLNTN
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme. Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.
Sequence:
MPYFPFCSHLQYEDAYAPQNLRNWGLPRVTKAHPSAREGYTQFIADDKGHLLPLIPRSKASPWGTYLGTWDMPLKIPPAKVNLTCRSVDAAARLTEWVNKAEVLRSACNGFSPEIVGKPSDPPAHPTKETSAKLGGPSSRGSEGKMPAQEVVKSSGAATPKHPLSRQPGSIDVRLKKEAPPDVPSFQQPDPTEVRQRSGSQIPLSRQPGSMDVRVKDTASLKTSATSRPNSREFTPPRRTISAEAPALSRPRSLEGKAKGVSTSELLASCRPGTMEANPKSALSLEALSPSRPATKASHVSEISKDGNRSEREGATKSRLEETSS
The following text describes a protein:
Function:
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.
Subcellular Localization:
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Sequence:
MDQLSEWAIQAKNALSQAQQYCEAAHRIDEEAMNMLQHYQKQHERLKELSKLTASQCSRLDASTALIQQLLSLVQKHPTFNQLSQLHEQLEAALKRLRETSVDLAFGCNHDNLYAFVDDTALEDLKTRLRCVTDSVWNAYERLVGLLDEGLCSQYRTRLLNTNLEFAVPTNNSVAEELADLLFQVAQHYEQCTKAVEIYSTLDEAASRELVEVLREDSEHLPVVLAQLKSGLDSTRAFQQSVNDYSSNIQAASVQLEPLAEELNKNELTNQRHEAAHELIKAQTGIEIPQLAQELIQLRNHYTQFAKTYNSLLDEVRRRRAYETRMRGLVRDFVTKLEKEQSGESEARVAFLNRHGDFLPQTLWPAVTDPPLHFEITEHQYSELPDIEDRSTKH
The following text describes a protein:
Function:
Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments (By similarity). In skeletal muscle, required for costamere localization of DMD and betaDAG1. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption. Required for intracellular adhesion and junctional conductance in myocytes, potentially via stabilization of GJA1/CX43 protein abundance and promotion of PKP2, GJA1/CX43, and SCN5A/Nav1.5 localization to cell-cell junctions (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell projection, axon. Cell membrane, sarcolemma. Postsynaptic cell membrane. Lysosome. Cell membrane, sarcolemma, T-tubule. Note=In skeletal muscle, localized at costameres and neuromuscular junctions. In bone marrow-derived macrophages, isoforms 2 and 3 are associated with lysosomes.
Sequence:
MSEEPKEKPAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVVTEEIMTTTTITEKHKMNVPETMNEVLDMSDDEVRKASAPEKLSDGEYISDGEEGDKCTWFKIPKVQEVLVKSEDAITGDTDKYLGPQDLKELGDDSLPAEGYVGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLAELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDATPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKGLPQTAVCNLNITLPAHKKAEKADRRQSFASLALRKRYSYLTEPSMSPQSPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGHPSFQVELETPMGLYCTPPNPFQQDDHFSDISSIESPFRTPSRLSDGLVPSQGNIEHPTGGPPVVTAEDTSLEDSKMDDSVTVTDPADPLDVDESQLKDLCQSECAQCWASVPGIPNDGRQAEPLRPQTRKVGMSSEQQEKGKSGPDEEVTEDKVKSLFEDIQLEEVEAEEMTEDQGQAMLNRVQRAELAMSSLAGWQNETPSGSLESPAQARRLTGGLLDRLDDSSDQARDSITSYLTGEPGKIEANGNHTAEVIPEAKAKPYFPESQNDIGKQSIKENLKPKTHGCGRTEEPVSPLTAYQKSLEETSKLVIEDAPKPCVPVGMKKMTRTTADGKARLNLQEEEGSTRSEPKQGEGYKVKTKKEIRNVEKKTH
The following text describes a protein:
Function:
May play a role in the development of the central system.
Sequence:
MEVPRLDHALSSPSSPCEEIKNLSLEAIQLCDRDGNKSQDSGIAEMEELPVPHNIKINNITCDSFKISWDMDSKSKDRITHYFIDLNKKENKNSNKFKHKDVPTKLVAKAVPLPMTVRGHWFLSPRTEYTVAVQTASKQVDGDYVVSEWSEIIEFCTADYSKVHLTQLLEKADVIAGRMLKFSVFYRNQHKEYFDYVREHYGNAMQPSIKDNSGSHGSPISGKLEGIFFSCSTEFNTGKPPQDSPYGRYRFEIAAEKLFNPNTNLYFGDFYCMYTAYHYVILVIAPVGSPGDEFCKQRLPQLNSKDNNFLTCTEEDGVLVYHHAQDVILEVIYTDPVALSLGTVAEITGHQLMSLSTANAKKDPSCKTCNISVGR
The following text describes a protein:
Function:
Component of the packaging machinery which encapsidates the viral DNA into preformed capsids and transcriptional activator of the viral major late promoter (MLP). Binds, along with packaging proteins 2 and 3, to the specific packaging sequence on the left end of viral genomic DNA and displays ATPase activity thereby providing the power stroke of the packaging machinery. The activity of packaging protein IVa2 is stimulated by protein 33K which acts as a terminase. May be the protein that pumps DNA into the capsid powered by ATP hydrolysis. Specifically binds to the 5'-CG-3' nucleotides of the repeats making up the packaging sequence. Component of the DEF-A and DEF-B transcription factors that bind downstream elements of the major late promoter (MLP), and stimulate transcription from the MLP after initiation of viral DNA replication. DEF-A is a heterodimer packaging proteins 1 and 2 and DEF-B is a homodimer of packaging protein 1.
Subcellular Localization:
Virion. Host nucleus, host nucleoplasm. Host nucleus, host nucleolus. Note=Located at a unique vertex of the capsid. Present in about 6-8 copies per virion.
Sequence:
METRGRRPAALQHQQDQPQAHPGQRAARSAPLHRDPDYADEDPAPVERHDPGPSGRAPTTAVQRKPPQPAKRGDMLDRDAVEQVTELWDRLELLGQTLKSMPTADGLKPLKNFASLQELLSLGGERLLADLVRENMRVRDMLNEVAPLLRDDGSCSSLNYQLHPVIGVIYGPTGCGKSQLLRNLLSSQLISPTPETVFFIAPQVDMIPPSELKAWEMQICEGNYAPGPDGTIIPQSGTLRPRFVKMAYDDLILEHNYDVSDPRNIFAQAAARGPIAIIMDECMENLGGHKGVSKFFHAFPSKLHDKFPKCTGYTVLVVLHNMNPRRDMAGNIANLKIQSKMHLISPRMHPSQLNRFVNTYTKGLPLAISLLLKDIFRHHAQRSCYDWIIYNTTPQHEALQWCYLHPRDGLMPMYLNIQSHLYHVLEKIHRTLNDRDRWSRAYRARKTPK
The following text describes a protein:
Function:
Component of the centrioles controlling mother and daughter centrioles length. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Nucleus. Note=Localizes to centriole distal ends.
Sequence:
MSASKEESLSPDEMRQKLYQTFKSRGLLDTLKTQLRNQLIQELQAPVRRGESASRRSADHTDSVLVSACNSVVVDHLRSAGYEYTLSVFQPECGLSKDKVLSSRDVLQIMKISPHMPLYKSLVSNIQSGQSGFLKSLLMELTDHSVYRDCSDNSTQTTSIAAHKESLVEKMQLIDEEYEVLRHRGDRWASVEAKLAEYRKEIQEQAQIELNAKLQHFMDVEIAKVKQEEKERSRKEILELRRDMEKTYELKSEALISREKNAIERLQKHQEIEEKDIYAQRQAVLREIESVRSREMELRQRMEAFDKSCALHEEKVKTMEDLLRRRELSVKTMEDSFEQKLKSELLKYQLELKEENMKRPEKLTENEERIRAEAARLQKEAAVVDAKTEDYERKSSEVKQLLMELESSRSQASLLKQQKELLREQLENMRDYPELKKHTLELQTRISLLKQQLEEKQQHNQRLTQELSAPSHEHLMLQAELRRLEAEHKLEKEELETQKNVLHTQLQHEVQQCALLKTQLMECEERTKWMNTHTEELKLQLQQTQQGPALRGPKSRTVAPEHDSDMVISALSRIRELEQEAERLEEAYRSHQQRALSAEDPTLHRGSQNYSRATAAQQHRVISRSPIFAGRPIEEEHEEFSRTPSPAERLASPPARRLSSTPQSASRSKRRADEEHDEHSLNPECVKGSSNTDRPALMFPERLISPIPAEELSSSISPNSPVMKSTTRHTQSPAKLQEILLSSSSQESSPQPEKITLHDLTEPIQMVSADQPCLLKDCEPELQQDHPDVQISSSSSSSSSSQREEEQQRETHTLQQQPHEEQTQEQRDDAGGHVTSAASPTGGAEEANPLQRYMQMLMQDKQQEQSPNKESSGSHEENLQSESHEHSAGVISHDEADDDFW
The following text describes a protein:
Function:
The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance.
Subcellular Localization:
Nucleus.
Sequence:
MSNSAPARQYLNEKVTPVLLEGMKILARDRPENPLQFLGQFLLDANANQQKQKEIVNQPEPQQETPKADADMSTPTMAEQVQTSFSNPASTPLTQTSSPSSNPGKNSAS
The following text describes a protein:
Function:
Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MRRMFLVSRNGYKRWPEKQKLQTFRVLISTYIFSQPPILAQYHTIPCSNLKLYCRRPRSTMAKKNNKKSKAKAKKAAPSVAVPATNVASSVAADPAAVETASSTSASLSVPESAAATETTASTSPTSPVTNVSPLAEAIAGDEGSGSIPDDEEDIDEEEETGTEESAEAEAEPESPEGTTPVLTVQPNALAAEPTVETVDVVVPVPVEPEEDEQESEVKAEIDPVVAEIEQPEPPMASDKDFFSTLSKEEDGEEDVKEVATSTTTDVATPVATATPSITQVEKHLESRFMGNPVVENEKKHKEDEIREVEDQLTERLMRDPVVEGIKRERAEESAQVEEKLEKRFMEDPVVEQIKQEQADEYRKVRDQLETGSEEPNDDFFANLGSEEAKLQAKDTEPDTKHEDDFFSTLGGSSDETGKKTVAETQSEPETKTIETAKAEEAKPIETKTEPVAEDDFFSGLGKSEQEQGFVPEHTTAASTTTKEEDDFMASLAQPQNPEQTDPLPQDDFFSQLAEENVQSVSAEPEHKSPVAAPAATKAAAAEDDFFSQLGKSPEKSVPAAATSDDAPRRRHKVQPSGADFFDQLGVSETEAPPALHEPPQPKPITLSLDEDDDLLLTDEDDQAEVLAEAGKPNPPVQSFAFLEDDDLLESDQDFLETDDEDEEPMAAQTGGDFRANQQHQNTYFPSVPVAPVSTSRYSTPTVPSVSQFGGYGAAQSTPNMYQPVSSQSTPSAAAPGAGKRVDKNKSDAFDFPTGMIPKVVKKARSQQQLPQAHGAPGVTPGLMPAFGAAPGAPPTPGVPPMGPPVARPASNPYAPAPVQPPTTAPKKNFFEELPPIPVKPISRQPSYALSPPRAPFAQEASQQPRRVSDGYGMPSHGGPHSGVHSAPVSHHNSVSGPPAAAPHNPYAPPSGPSAVPPKTSSPYAHPPAAVPPKTSSPYAPPPPAVPPKSSSPYAPPPVSHSAPPAGGPPAGPPRGTSRGVPVPQPQPPVAAAAAAAAAAAAAAGTASGPPPAGPPRVSSRNAYAPPRGAPPRGTTPPVVAPAMAYSPNVSPKRVIQQPQTQSPRRYSEFKDIGQKSTVSDEALRKRQFPIFRWSNSKNATCLIAPQIGYATAVSQTSVRLLDVSKVVSTGEDITRFPGPLFTPNKGPVKSKKKELEKWVADHVNLLDSQNADADRVLLWKLVRVYLANDGVINSAQVRAFLTPHFEQSATGDGSAFTSAMDLSSSSFVPQQGDNGPSFSGSDANHVLRHLQSGSKDAAIRHCMDRRLWGHSMLIASTMGPEKWKDVVSEFIKDDVRPLYKPTLQFLYSSFGGVIPSSEAYGDWKETVSYLLSNAKDDGSDLSSLVSLGDDLVQKGYVAAGHFCYVVSRAPLTDKITLLGSEGRDLDAILLSETYEFALGLKTNVAIPQMQLYKLVHAEVLADLGNVAQAQRYAEYLNQALKSFTDKSSIIQPAYISRLIALSDRVSSTPGATTGSWFSRPKLDKVLGHLDKSLSKFVAGEEANVAGASSASDTVFSQIAATPGISRTTSVVDLSQQSAVTPGYQQHQPYGVPPTRASTGNILRPQGGSGPYDSRPSLPRSSSAMDAGPSGYGYERAPSVASVHSVQSDYPRVMSPIDVGGVSGGNSAYAPVGGAGIYPLPAGGSSAANAYAPGAGGNANAPPSGATANAYTPGATSSGPSPYALPSGNVYAPPSAPSASGASPYAPSASSFSPRQPAYGRSYASTPEHHIEEEEETEAVDQEQEPAADYSHLENENERYEQKSEPEPEPMAHPPPAQKAPPAAPPAQQAPAQKAGQKPPARKVAPPPKPSVKSVYNPYDPGSPAKEKKSSAAASNKYAPANSAYSPGNSSAPAPTANKEPEPATTSEAYGYGYGGGYGGYDPYSGYPAAEEEGAEPTETEVENEKAGEAEAAAADYPDYGVPSYGYQSQAADDAGDYGDDEGAIYTPAAVTLPPISNLPPVPLPGLEPATSAAPPASRYSAPTAAAEEEDDDDFGVGNKKPVAKKEEKKAEEKEEPKDGGKKGWFGGWFKKGEQQPADDKKVYKAKLGEKSNFYYSEEHKRWINGDLPIEDQIKGAGGPPPPPKAKKPAGPPAGGTPPPPSGGAPPVGASRGATPPVATPPAADTPPVPGAGGAPRPAATGAPRPKVVDPLEGFLTGGPPTGAPRKGARKSAKSRYVDIMNN
The following text describes a protein:
Function:
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDLVQSAVLYSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDERVTNWVDAGNAMDVAYLDFSKAFNKVPHDLLANKLVNCGLCKTTVRLICYWLIELICIYIHMNDSILNATCNIWGGGGTATNLCTRLRNCKLVIPTTKMEQCFSFE
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MEGKKLRHQRKVVGLAILLINDQQDDINPSTFTCDFCVESKHLQESFKVKGCSHFYCDQCIVKFVVSKLQDNVTSIMCPVPGCKGMLDPEHCRPILPNQIFDRWGSALCEAVVMGSETDKYLYCPFKDCSALLVYENGTKRAVCASVCPHCKRELCPSCKVPWHTEFDCAQFQKLNDDDMVKVLARKLKWPRCPSCKYYIQKSSGCNRMICRCGRGFLYNEPSYSFYDRIRIFLEETPIFLNEIHISFLKETRIFWNKIRISFLKEIQEARISFLKETRIFLKEAQEARISFLKDTRIFLKETQEARISFLKETRIFLKETSISLKEILIFLKERRILFLKEIHIFLKEICIFLKGE
The following text describes a protein:
Function:
Required for nitrite assimilation. Required for activity of the reductase (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MVNKDVTKVCIGKIEELPEQLGKTVYIEDKELAVFKLSDGSIRAIENRCPHKGGVLAEGIVSGQYVFCPMHDWKISLEDGIVQEPDHGCVKTYETLIEGEHVYLVY