lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Subcellular Localization:
Cell junction, desmosome. Cell membrane; Single-pass type I membrane protein.
Sequence:
MVRLFPSALVVLVLLQVAIVVRQTSGENLVRKRREWILPPKPLKENKDYTKELSIAKIRSDYQQGSNVEYFLEGPGANQRPFNVFVVNHNTGDVSVTKVLDREEIDTYVLKGVAKYEDGTEAEKPIDLRIKVEDENDNDPVFPDMSPVGVYELSPKGTIVMELNATDADEYGNLNSKLAYTLISQNPSHDMFRISKKGVITVKNSSLDRESCAQYTLTVEAKDLDGAIGGRTATGTVTINVLDVNDNPPILEKQQYDGSIEENTHQVEVMRFKALDQDLEGTENWEAVYEIVKGNEAGYFSIMTDPKTNEGILMLEKPVDYEDVKSLDLGIIVKNKAPPFDPSTASNGVGVNFGGQPGGASGASGASGASGASGASGASGANGASGATGPGGATGPGGATGLGGATGPGGASGGSTGISGSGSSSGYKYTSYPITINVKNKPEGPSFDPQVKSVPISEGSDISLKRPITTYTAIDKDTGKPAKNVRYLKGPDPGNWLSIDPDTAEITLNKMPDRESPYIINGTYYANILCISEDIPGKTATGTIAIQVGDSNDHCPTLTSKSQVICMTQNSFIVTADDKDSFPNGPPFHFVIVPEKTQGKWKVEHLNDTAAIVRAQEELWAGSYEVELVVSDQQGLSCGEPQKVELLACTCDVGDECGAHGSQGQSKKQIKLGPAGIGLLLLGFLMLLLIPLLMLSCKCGSPLKNPELFAQMKEDTKGNFRDWHTEKQEDLGVYPLMNAPAQIYIDSAKGYLTTAPLEMQKSFVGSNTLGGGYRDAANMHSEGQGWMNQWGSDLYSGSEVQDFGYGGGAGLVLPDAFFRDFYSEVTSKNDTDVVKDTMMVYDIEGQGSDAGSLGSCKAMEQNEDLQFLDDLGMKFKTLAEICVVKTIMSETKAVSSPPPVPSLSTPKVSESNLFTTQRMTPPPSLPLTNIREERRMVSDIISPPPVPSLSTPKVSGSKLLTTQRMTPPPSLPLTNIREERRMVSDTTNHSQVLKKDVAVVSEGVTSMATGLESQSQMLVLQQEQQPVYYSAAHMMQPMHYMVQPQFQNFILTEPPANSLQDMVLLNSSEMGYNPGVIIQGQTMMHNGHVQGTGTMLLENSSHTNLIQMGNLSGSQTMMVVEGPVSGSMNRVQSGLIQGQTMMHNGYVQGTGTMLLDNSSHTNLMQMGNLSGSQAMMVVEAPVSGSMTGVQSGLIQGGTLGSVTGVQSGLIQGGTLGSLTGVQSGLIQGGTLGSLTGVQSGLIQGGTLASGQLSGTQGVLKVKEATSGRGRAGKTERSRVVNTKGSNQTSTSSTSFSVPTSTTQKVLIQETAQIR
The following text describes a protein:
Function:
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
Sequence:
MPQSGIVKYHVKLSYEVDGLVERADIIGAIFGQTEGLLGPEMNLNELQRVSKVGRIEVSARTTANTTAGDALIPMSTDIDTCALIAAGIESIDKVGPFDCKFTLEAIDDVRAAKKDDIVKRAKEIKQKWATKTVSEGESMLNDVHQGDSKKLTTYGPSKLTCSSGLADSNWVILVEGRADVINLLRAGYDNALAIEGAKIDESIKELCNSKETVVAFLDGDRAGGFILKELKSVVPIDYELRADNDVEVEELTPQRIDEILSPVAEEIKGGKPAPTLQNEDDKPLAEMAAKVFPNLNETLEAVALDGDNNEIFKVPISEVVSKLSTQSGIKYLLLDGIITQRLLEGAKNAGIECVVGHRVAKLSNSDGMTLKTFGDLGVA
The following text describes a protein:
Function:
Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via T3SS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal.
Miscellaneous:
MISCELLANEOUS: Deletion of amino acids 1-20 abolishes invasion activity, affects contact-mediated hemolysis activity and IpaD secretion. Deletion of amino acids 41-80 and 81-120 restores invasion activity to a higher level than wild-type and reduces contact-mediated hemolysis activity. Deletion beyond amino acid 120 reduces invasion activity and abolishes contact-mediated hemolysis activity.
Subcellular Localization:
Secreted. Note=Secreted via the type III secretion system (T3SS). Localizes to the tip of the external secretion needle that is part of the T3SS apparatus.
Domain:
The N-terminal domain is an intra-molecular chaperone that prevents premature oligomerization of the residues on the coiled-coil region that are involved in interactions with the needle and/or itself. The residues in the C-terminal domain probably form oligomeric structures at the tip of the needle that are responsible for the regulation of secretion of other effectors.
Sequence:
MNITTLTNSISTSSFSPNNTNGSSTETVNSDIKTTTSSHPVSSLTMLNDTLHNIRTTNQALKKELSQKTLTKTSLEEIALHSSQISMDVNKSAQLLDILSRNEYPINKDARELLHSAPKEAELDGDQMISHRELWAKIANSINDINEQYLKVYEHAVSSYTQMYQDFSAVLSSLAGWISPGGNDGNSVKLQVNSLKKALEELKEKYKDKPLYPANNTVSQEQANKWLTELGGTIGKVSQKNGGYVVSINMTPIDNMLKSLDNLGGNGEVVLDNAKYQAWNAGFSAEDETMKNNLQTLVQKYSNANSIFDNLVKVLSSTISSCTDTDKLFLHF
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 (By similarity).
Sequence:
MNIKGIDVSFDAQKKEILEGLKSSVPDASPKGHPDSPIFPLLDVINSHPDWVTTSSCSGRISVYVQGANSRKGGGYWLFVSHQAHEELPPVLEDEKVEYGKVPSSPVEGNREIQYAFEPMILHVQTRSLANAQHLQRVAASCGFRETGIQGSEQKFIVAIRTSLRMDIPIGCLTASEKLQFYITREYMCFLFKRSVEYFTENGNRMARLKEQLERQVEKRMKPRRKLRNMDDYLVQS
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MADTNESQPVLRSTKPVSEALLNEKWDRAISSMIIRSSLGLSFGVVFSVLLFKRRAWPAWVGLGFGAGRAWEEADASFRRGDSPVRDALRK
The following text describes a protein:
Function:
Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.
Miscellaneous:
MISCELLANEOUS: Present with 3170 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPPLPVLNRPQIHTSVTEISHAIDRTIKEELFPVAYTTEEEQYFKTNPKPAYIDELIKDAKEFIDLQYSLKRNKIVLITSGGTTVPLENNTVRFIDNFSAGTRGASSAEQFLANGYSVIFLHREFSLTPYNRSFSHSINTLFLDYIDSEGKIKPEFAENVLKNKKLYDKYMEKEEKLLLLPFTTVNQYLWSLKSIAKLLNNSGCLFYLAAAVSDFFVPYSRLPQHKIQSGDNGKMGANNDTEGTTRTTPDGKLIVNLDPVPKFLRRLVESWATQAMIVSFKLETDESMLLYKCTQALDRYNHQLVIGNLLQTRNKQVIFVSPENRKGDWVRLDEKHHSIEEMIIPEVIARHDKWVAHSKTKLATK
The following text describes a protein:
Function:
Functions as a two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Domain:
Histidine-containing phosphotransfer domain (HPt) contains an active histidine that mediates the phosphotransfer.
Sequence:
MPLRLFWSLILGLVIFVNHSSIFITCMLSMLPRTHSIPLELQSVKALWHGQFLPLQQLQDESNPDFVVEVVFLFFDDSKKLLNDLTIAFIAAQRVKNACIAFCNFFEEQNIATCLRCLQQLYAIFV
The following text describes a protein:
Function:
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of CO2 levels and acidity by the BAG neurons. May act as a direct receptor for CO2 and H+.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell projection, cilium. Note=Localizes in cilium of sensory neurons.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MRLYLFFISSLLLAESRRSISKISHDEINQHVKTTLSSEGIVRIGHLHPTNPIIAHEPDVLKMCADDLKMRNILPQNYTLTVFTMESCNKYSGVEHAAFLHYLKNASVYFGPGCNNEMLVIGRLAPRWNVPIIAHMSGDDALSDRVQFPTLGSVALTSASEMAKATVTYLNLNNWDQIGIVRPSVGYERLSVYSLQHQIKKRDINLNVILDIEPFSSPEEIISTGKLTTLKSMARIIVVELGMDIHSVTNFMLAIHRSEIKNEEFVFVIPWLAHQNDHYPWEAANVDKQEVKLAFENTIIITAHGYDKKFFDDFQMKFSAVTGVLANHYATLSYMSLYDALFLYGLALRDAFEDGGGYNVHMNGSLIWSRMTNRQFIGMTGQVLMNNKAIRVPSYATYHAINGTLKIVVELEAKNNDRGQCEKNEEMCSEHVAHETIQYYWPSDSGKLPPAVPKCGFTGAECDYRPYFIGASLLAFILTVGPLSYFIYLKQKERLLYDMTWRIPRESIKMLEGKSKSEHSLASKSQSSGSFSGSMNSKQNGLIAAKQAVSNGVKLAIKRYQQVRNITFPKSELRLLKELKICENDNLNKFYGISFNQQNEFIVMWVLCSRGSLEDILFNDELKLGRNFQVSFAKDVVKGLNFLHTSPLLHHGMLCLQNCLVDSNWTVKLTNFATEAVIFEKLDHNELRPFINTDSESADDVSDPTKDFARKKYLQQAPEIIREIVTTKTIPEGSQSADIYALGMVLYQILFRVEPFHERNKSINKLMETLAMANDDDQLIRPTFPSSNTGEGYNLQLLSCIEACWLEIPEMRPPIKKVRTMVNANLKSTGKGSLVDQMMKMMEEYTANLENMVRDRTALLEEAQKQADRLLNSMLPKSIAEDLKIGKPVLPQLYSCATVLFSDIRGFTRISSTSTPLQVVTFLNDMFSGFDAIIAKHDAYKVETIGDAYMIVSGVPTENGNSHAQNIADVALKMRAFICNFKLAHRPEELMMVRIGFHSGPVAAGVVGLAAPRYCLFGDTVNTASRMESTGVANKIQISEGAYNLLHCFFPQFQMVERGKIEVKGKGECLTYYLEGRTGKQ
The following text describes a protein:
Function:
May play a novel role in the growth or remodeling of bone.
Subcellular Localization:
Secreted.
Sequence:
MSWFLVLKCLLTVCIISHLSVSSTESYGCIRKTCFGGRCLHNTTRSCEFSKGCFSQLQEFAVPLLLLNRRVEQRGCSEDNCTELAFSATLGIDWMFSYNHQCCYSEQCNNKPINVSPLSLQPNGVECPTCYSELGTCRPVSLKCTGAQTTCVNVTGQGIREDFIKIHAMGCATQTACNLKNVIILNNIKIDTSCVSGSPPLRYSPSLSTDQKTSSATAPTLCLLAAVLPAIMVMESFSEL
The following text describes a protein:
Function:
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
Sequence:
MSKTTEIFCRLPKSVELIQDFKDITPSPKANAECRAALYSKNGDFFAYTQPQEVVILDTTGEAKVYHRIEIPEVFDIYFSPEGTYLCLWCKPIQLNKENGTWNNNLKIFNIKTKTIIAEWSAKHQNAWKPQFTSEENLFARSINQKEIHFFELDPTSDSTVNINQPSFKYKVNDPKATLQAFQISPGRNPSVAIFIPEKSGKPANVSIYNIPNFNQPICFKNFFKAEKCQLKWNSLGTALLALASTDHDTTNKSYYGETNLYLLGIAGSYDSRIDLKREGPIHDITWSPTAREFAVSYGYMPSETTFFDSRGNAIHSLPTAPRNTILYSPHAKFVLVAGFGNLQGTVDVYDRQNKFSKVVTFEASNTSVCEWSPCGRFILTATTSPRLRVDNGCKIWHASGKLIYLKEFPELFSIGWKPQPLDCFPPIRNLEPAPEAHESTKEYLEKRQALASAAAKKPAGAYRPPHARGGGAGSGSGVASSLYQKELQNNLRSNGSTPSPPPGLSRAAGNIPRVRTVVGAPPPVEKESKAAAKNRKKREAKKQAQEKNNSPAPEATTSASPVPAQAQAPASTPAPTPATAGVIGGVASLEEKKIRSLLKKLRAIEQLKMKQASGETLEDTQVIKISKEDEIRSELQTLGWNE
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MELNSLSGILAELKEVYGKQKSHFRGLDIFALFGIMVALIQLVYSGLTHGYPFCSMVSAVCMSLGFTVLVISLRLHLTPEIESSISNYRAFAEYIVALSLLFLFGWNFMN
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus.
Sequence:
MNRPQRKLSVSGRPSYQGGSGQSSLKRSSAATPLMRSSLKRQPLSAVKGNQRSSYVNTDHQIIKDTRPLSDKSYMKKCVFDLIHLLNDLHYPTSLSPKMLNPPTNREYQRIFEFLAITLAGNFRIIKPDEDMMRFVKACGYPYSLSKSTLNNVGPMSSWPHALGVLMWLANQIKIAPDLWTEEEMLEPKQHVQQQFFHSVYNEFMSGNDGPFTETENEARRMLGEINKDTLSEVQSLETKFENLSATALKNEEEKASNIKLFEQISTKRQNIEKMEKYFDDIDKYNSDKQARTLEFNELTASKDEEGNDLRLKILDLETEVAGQEMSKDDVYQHKVKNEQLKGSVISTAERIETLKKTGWELEIETAKALTAMNDRVNVQNNSMQKLWSAVARRLELNEAVKPPALLSGALGFEGNRSKQIDSVQPFMMDLNERLLAHQRKLNQELNDATNRRLQEREMIQDVQKSINILETAADQVHAEIQNFEEERTKKVGTLRSETDKEKTKKCQFIAMNTESVEELEKQVELLQNENLKQGKSFSKQKEDAITEIKELVAQLKEFKIKCNEEIEKFYENIIQQNKNFADNMNEVARSLPTVD
The following text describes a protein:
Function:
May play a role in the regulation of cytokinesis. May play a role in signaling by stimulating protein glycosylation. Induces neuritogenesis by activating the Ras-MAP kinase pathway and is necessary for the survival of cerebellar neurons. Does not appear to play a major role in ciliogenesis.
Sequence:
MIDIKQNITDKNYDKVLETLNALNISETDADSFRCEVDILLESFYVCHGSEEETVNRIAIKCLNLLKRACARGESFQNAIVSRVEFLERVRDILVDEKKTIPENVRTNCLQLLANLCVQNRSNQERIITYMQTFLLTNVSSNGSYANASAMILYNGFIYKAVDLNLHDVLARLLDNVEANQTAQTDVPEFVCIFLEYLIAESNEMVQVLEKIDVSKKLLLYRYLIEYIRQEDRRIHPIHPDVFKHLLAEFKKKSDMILKTDNVQLDAQDTEEAFTLLVMVADSTCVEPYGSFLRHDGGLFLNLGCLLRQMQLLGKSETKNMFTPVQKIEEILRIKQGDTELDIESQISYSLRSAVVKGLANLTYKSKKNQKLAREMDIIAAILECTNLDARNPLIKEWSILAIHNLCDDNLENQQFIAGLKKLGDAENSLLTEYKSGTIRISDGKA
The following text describes a protein:
Function:
Component of the insoluble proteinaceous cement which allows underwater adhesion to rocks and other surfaces. Shows specific adsorption on calcite substrates.
Subcellular Localization:
Secreted.
Sequence:
MKWFLFLLTTAVLAAVVSAHEEDGVCNSNAPCYHCDANGENCSCNCELFDCEAKKPDGSYAHPCRRCDANNICKCSCTAIPCNEDHPCHHCHEEDDGDTHCHCSCEHSHDHHDDDTHGECTKKAPCWRCEYNADLKHDVCGCECSKLPCNDEHPCYRKEGGVVSCDCKTITCNEDHPCYHSYEEDGVTKSDCDCEHSPGPSE
The following text describes a protein:
Function:
Thiazole kinase involved in thiamine salvage pathway.
Sequence:
MKHAATIIVEKFGAAAALIKGGHMQGDAIDFLYDGNTIHSFSAERIDTRNTHGTGCTYSAAITAYLSQGLPLYDASREGEDMNPNIIKKVREKTPLIHHLTNQVVMNFTANGLLAFGGAPVMAKAEEEAWDMASVADGVLINIGTVREDEVKAMILAGKAANEKGIPVVLDPVGVAATAFRTEVVKRILAEVKPTAIKGNAGELAYLVNIPWQTRGVESIGDGNTQEIAQKVAEVYSTISVVTGRTDFICTGNQMIQNKTGHAILEKVTGAGCLLGSILTACLTTNDSIEEQALTAVQFYGLAAEYAASQSQVHGSGTFIPRFIDALSLDAKELERRI
The following text describes a protein:
Function:
Component of a protein kinase signal transduction cascade. Mediator of TGF-beta signal transduction. Responsible for activation of the JNK MAPK pathway (basket, bsk and hemipterous, hep) in response to LPS. Component of the NF-kappa-B pathway; relish-mediated JNK inhibition involves proteasomal degradation of Tak1; certain targets of Relish that are induced during immune responses may facilitate destruction of Tak1 and switch off the JNK cascade. Participates in diverse roles such as control of cell shape and regulation of apoptosis.
Sequence:
MATASLDALQAAYVDFSEITLREKVGHGSYGVVCKAVWRDKLVAVKEFFASAEQKDIEKEVKQLSRVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLIHRDVKPLNLLLTNKGRNLKICDFGTVADKSTMMTNNRGSAAWMAPEVFEGSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVMHEIVKDYTGADKALEYTFVNQQIVTKESDGTVAAQPDSLSSQEGELSPSSTQLTPTTAANANVNAIAISKTTTSSMTENTSSTSSDITPTNSGQLDNNPLFYMVTNRWDAIPEEESNESRNDSFNLTSSAEATQRLETIRNGMILMACKPMEQLTLDVEANGFDLSPSESSSSSTNAKSDGRERLTVTDTKPVMMTTDLSNNNGGIHAHSNGLLSHANGWQARDEELQEQEHEQEIVNSLDVDVDPDEDENDGTEQSLAEILDPELQPEPPIPNDAESQLIYRDHRHMAKEYLSVDTNLYYAQDFKDKLIVQMDRTEREQKQELLRKMKDKEGLQSLYNNLQQQYASRQLAAGHHPQPHPHPHPNQLQHPHSHPPMHFLQDEGCGLLPGSVCGGSESVEEGWVVIPPHHNA
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MAPKKPKLSPRKLSVTSQKSKLTQKPDGASVGISHSPIVEPPLEKPNPIVFIDVKIGGQEVGRLFVELYEHIVPKTADNFLKLCTGVKGLGKQGIKLTYRRTVFFRIIPGVYAQGGDIIKNDGTGGESTFDGIPFEDENFRVSNARIGSLAMCNTGPNTNESQFFINLAPNPDLDGSHVVFGQVKEECRPVLKAMEAAGSWTGRTHQKVSVKSCGWVNKPSKELSGMSEETAEAVRLKTEVAAVGTADEH
The following text describes a protein:
Function:
Involved in nuclear control of mitochondria.
Miscellaneous:
MISCELLANEOUS: Present with 2280 molecules/cell in log phase SD medium.
Sequence:
MALANSRPLQIPTLENEILHNSNSPVFQLNSMGFTTRADTISNPGTDLIGNQPGMALDDNNLAGSSFSSSQEIKATKPKKDFGAPKKDNPLLEISKLIPVTGERPKPENRDSPLDDDVLHAVFLILWEMDPNQQGMTVKQLCDLLLQKHPDMSNLSTKLSNLISAKLNAYVKKIEKGEKTLTYALSREWSNSSPRRMLYIYRGILSPDYKEHAQAVTMQLKQQLETSGDTSDFNSNGKKKRESSSNQLVNNDSYSSSMTDMKNMSSNSSFSKNLNVGNLAFSLSPEFNIPYSTSPVSLNLSPSMSNNQQQLLTPNSASKSKNNNKKRNYMDEDTNESMTEPKKTKTTKPGKQTKSQSLSVLSTPKKGSSASLSTFASSKNISPDSSLSHNASSNTYVTAAAAAPRLSKLLPKNGFKKNSRSSSELAAIHKVISTQTPIESSSESSQYNSSSSSPVNSAAASSAESLSDINSSQDNGRESNPSSQESRNEVTNWMKIVRNGFLTHDIESPESITLDDLENIFN
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MELAMNAELLDLKAFITVAETGSFVRTARALNLSQPALSRRIQKLEESLGAPLLERSTRHVNLTMTGRDFLPKVRRLIDEFETSVLAIHDIGARSSGLVSVAAVPTAVFYFLPRAIGRFAETYPRIRIRILDIGANEGLEAVARGEADFGINFIGASHAEIEFEKLVEDPFVLACRHDHPLASRKRVSWSEIVSHRVITVGRNSGNRALIDNALARHGLQLNWSYEVAHLSGSLGLVEAGLGIAVLPKLATPAAGHPIIHTVRLIEPEVSRTIGIVRRRGTTLSPHASQFLKMLLEAWHTPSGTRGQDKPKPRSAQANSIRRA
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MDSSFKRASFKLPPGVNIDNINEMNNNNMNTAPAPAPAPIPTPQPTTTTTTAPQRKVTFGSRVRAQEINATPTPTTPAPAPTTTPSENDTAKKDDFDFDPVPVSRPRATRAATMIPSNMLGDKRPIRPLGKGFIGADRQTPKPETDNNNNGNNNNNNNNNDNNNNNNNNDDDDEDEDDDEYSNVSAPSWNSVLSKAKTNTMNSRKRSGMIHDFVDVNIKNDSGGENSANTTSEDGSSSRRGTLRKAIVIGTHNPQPQQEDDVEETTSRISSLDLANVQRPRPQYHTIDPASIPQWKKNNEDLVNTMEQQQQQPQQPQQPQQQQSTVGGLFNSILKKQPNNNANNAQRLTRAEAEYNEYLTKSKSQRFPEIEALNFIYPAGKDNLGRTIIVIIASHLPVREMDMERVLLYTISIMDPVVEEEYVLVYVHTNMNNSNKPSMAWMKKVYTIFNRKYKKNLKGLYIVHPTTWIKFTLGIFKHFLSSKFWKKLTYIDDLGELFKTFPREQLALPNAIMMHRPAGKKSQPIFGAPLEDVINRPDNPGEIPVLFEKGIAYLSRRGLQVEGLFRLSGANSQIKSLRQGFDQGEDVDLEDVEDVHTVAGLLKLYLRELPSPLFPFDLYSSFIEISKGEQTKPQKVESLKLLLSLLPPANKALSKHLFKFLGKVIENSSVNKMNSVNLSIVFAPNLLKDKEGNVMDAVADAQFVNQVVQLILDNINILFNY
The following text describes a protein:
Function:
Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly during neuronal development.
Subcellular Localization:
[Isoform 1]: Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Note=Colocalizes with syntaxin vesicles along microtubules in neuronal processes; [Isoform 3]: Golgi apparatus membrane; Single-pass membrane protein; [Isoform 4]: Golgi apparatus membrane; Single-pass membrane protein; [Isoform 5]: Golgi apparatus membrane; Single-pass membrane protein.
Sequence:
MGPLRESKKEHRVQHHDKEISRSRIPRLILRPHMPQQQHKVSPASESPFSEEESREFNPSSSGRSARTVSSNSFCSDDTGCPSSQSVSPVKTPSDAGNSPIGFCPGSDEGFTRKKCTIGMVGEGSIQSSRYKKESKSGLVKPGSEADFSSSSSTGSISAPEVHMSTAGSKRSSSSRNRGPHGRSNGASSHKPGSSPSSPREKDLLSMLCRNQLSPVNIHPSYAPSSPSSSNSGSYKGSDCSPIMRRSGRYMSCGENHGVRPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLHERESEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDKGIQKYFVDINIQNKKLESLLQSMEMAHSGSLRDELCLDFPCDSPEKSLTLNPPLDTMADGLSLEEQVTGEGADRELLVGDSIANSTDLFDEIVTATTTESGDLELVHSTPGANVLELLPIVMGQEEGSVVVERAVQTDVVPYSPAISELIQSVLQKLQDPCPSSLASPDESEPDSMESFPESLSALVVDLTPRNPNSAILLSPVETPYANVDAEVHANRLMRELDFAACVEERLDGVIPLARGGVVRQYWSSSFLVDLLAVAAPVVPTVLWAFSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFRIKT
The following text describes a protein:
Function:
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.
Sequence:
MKTFSYTAHSKQVLGDMHTPVSIYLKVRDMYPQSALMESSDYHAGENSLSFIALCPLASIGVNSGIVTASYPDKSRKEEPLTQSFTVEKAMNQFISQFQVTGENKNVCGLYGYTTFNAVKYFEHIPVKESHDEQNDAPDLLYILYKYIIVFNHFKNELTLVEMLGEGEESGLPELEAAIENRNYASYNFSVTGPVSSPISDEEHKANVRKGIAHCMRGDVFQIVLSRRFIQPYAGDDFKVYRALRSINPSPYLFYFDFGGYRIFGSSPETHCKIEDGRAYIDPIAGTTRRTGDTVKDRELAEALLADPKENAEHVMLVDLARNDLSRNCHDVRVLFYKEPQYYSHVIHLVSRVSGQLNEGADKIKTFIDTFPAGTLSGAPKVRAMQLISEIEPHNRGAYGGCIGFIGLNGELNQAITIRTFVSRNNELWFQAGGGIVARSQDEYELQEVNNKLGALKKAIDLAVNLKN
The following text describes a protein:
Function:
Transcription factor that prevents axillary bud outgrowth and delays early axillary bud development. Indirectly required for the auxin-induced control of apical dominance.
Subcellular Localization:
Nucleus.
Sequence:
MNNNIFSTTTTINDDYMLFPYNDHYSSQPLLPFSPSSSINDILIHSTSNTSNNHLDHHHQFQQPSPFSHFEFAPDCALLTSFHPENNGHDDNQTIPNDNHHPSLHFPLNNTIVEQPTEPSETINLIEDSQRISTSQDPKMKKAKKPSRTDRHSKIKTAKGTRDRRMRLSLDVAKELFGLQDMLGFDKASKTVEWLLTQAKPEIIKIATTLSHHGCFSSGDESHIRPVLGSMDTSSDLCELASMWTVDDRGSNTNTTETRGNKVDGRSMRGKRKRPEPRTPILKKLSKEERAKARERAKGRTMEKMMMKMKGRSQLVKVVEEDAHDHGEIIKNNNRSQVNRSSFEMTHCEDKIEELCKNDRFAVCNEFIMNKKDHISNESYDLVNYKPNSSFPVINHHRSQGAANSIEQHQFTDLHYSFGAKPRDLMHNYQNMY
The following text describes a protein:
Function:
Sodium-independent nucleoside and nucleobase transporter with a broad substrate specificity. Plays a key role in the utilization of host purine sources by P.falciparum during intraerythrocytic development enabling parasite growth in the presence of physiological concentrations of adenosine, inosine, guanine, guanosine, xanthine and hypoxanthine. Essential for parasite transition from ring to trophozoite or from trophozoite to schizont stage but not for erythrocyte invasion by merozoites.
Miscellaneous:
MISCELLANEOUS: With an efficiency similar to that for uridine, can mediate the cellular uptake of nucleoside analogs used in cancer chemotherapy: fludarabine (9-beta-D-arabinosyl-2-fluoroadenine), cladribine (2-chloro-2'-deoxyadenosine) and gemcitabine (2',2'-difluoro-2'-deoxycytidine). Unlike the mammalian transporters, can efficiently transport the anti-viral nucleoside analogs: AZT (3'-azido-3'-deoxythymidine), ddC (2',3'-dideoxycytidine) and ddI (2',3'-dideoxyinosine). In contrast to the human transporter SLC29A1, has low sensitivity to the inhibitor nitrobenzylmercaptopurine riboside (NBMPR). Can transport 5-fluorouridine.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSTGKESSKAYADIESRGDYKDDGKKGSTLSSKQHFMLSLTFILIGLSSLNVWNTALGLNINFKYNTFQITGLVCSSIVALFVEIPKIMLPFLLGGLSILCAGFQISHSFFTDTQFDTYCLVAFIVIGVVAGLAQTIAFNIGSTMEDNMGGYMSAGIGISGVFIFVINLLLDQFVSPEKHYGVNKAKLLYLYIICELCLILAIVFCVCNLDLTNKNNKKDEENKENNATLSYMELFKDSYKAILTMFLVNWLTLQLFPGVGHKKWQESHNISDYNVTIIVGMFQVFDFLSRYPPNLTHIKIFKNFTFSLNKLLVANSLRLLFIPWFILNACVDHPFFKNIVQQCVCMAMLAFTNGWFNTVPFLVFVKELKKAKKKKEIEIISTFLVIAMFVGLFCGIWTTYIYNLFNIVLPKPDLPPIDVTQ
The following text describes a protein:
Function:
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MNQTYNNINHNNTNHNNINHNNINHNNHNNINHNNINHNTINHNNTNYDNNNNNQMVKSESEIVESPTASIRGISVLFGSFGRRKNSSRAKKMPLSKIYEKVFNLFIKNQDPVTGLIPQPNNQEIASAHDNVYAALTLWSLAISISKNSNLSSNHKKLPADLLKMSKKMMLSVLAGFEAQVKQKDEAYSKHFPGVDPFVHLDLTTGRPMENSGSSLINQLECGPTKIETVAFFLLVLAQMQAAADTDVDSIHDQIKFDDTSMRVSTLFMIKAVLYSFTILNSSKQKFGQYSVEAFHYEAIQAKLMLKHLVGKVISLKWFNPNAAGLTSFPFFAVTKQDVKEVIEKSFFEKQYKDEDASSKVSADFNKDKFEVYTYLCLSLLFSDDQPAAFLHKTYLDHFMNMAVDNFYKVFEESTGSDNSFSYVTCQSLNIIISLISNRYLEAKHIDSLNLSNLLVESKEKYQKNKEIQGYCVTDKEQKYTDAAEEAQDSVAALFRTCDMKEELKSLATTSQTDGSNYRRRELLYKRSPSNVIYTGQLYSIRNIHLIFIPRVGENPSIPSDLNRLFKKLQSGLVGGVRVKLTKMPRSPDSFLVSNLDLLAGSKREGSKEFLSVISSLSDFSYDNAKNVSNWSSGNVSSVPTADVAISSTSPPPLNLTSSTQSSPTDDQSQAVKMKFFNNEVKQVENETKNSLNSGIDQLLKQRLVTLANTTATGTDADAAINDGKTASSPDKKISPVDGAGNPANTTLTSQITSALTNAISSQRTNEQVQSVAQPTNVVPVVPEGGKKFSESAVTTASSFSRYAVSSHSTESFNNLLRSMDYQDDLKHKWLRIDVNWLPEQIIDFVITNTDINESTFPTEEECVHLLKLFDSSNNYMERAHILHKLYYSRGINWHPNLEDSGLNMTVRDALTEMYRMSGVWQIWWMVRFCGGAIGVHLNNLSVAVSDILTRRHKQLIVGCASNNKIVIAKPYRDLDIKSIINIVSRNNPFMICLIQEIIVYVWMIYQYNSVVVDQLVCIDVQALYQAMITDLCIRFDCNEVMASIYMGCLSPFELKCYIEATLKGTEITKAIDIFELGQNLTTQKDSGFLEHIDTYTQKGVWMRRRSVDGTLMRLPDEFIENVWDLLRVCKGLSFDGHLIKPETTDRYGKYNLNFTAVLYATLHFIKPPEYLQLLIEATYLLSSLAKNKRIKMNVKKVINVNEIVVVAVNLFLRQQNADRMKTCCTPSKNIRKPSVPVDSACKTRGGVCYHFYDSSPTGDFGTMAYFTDAILALHTEVGRNI
The following text describes a protein:
Function:
Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Sequence:
MEDYVIGVDIGSSKVCAAAGKRDKYGQAKIIGVTSAECHGMKNGIIIDIDSTAESITNCITRLESIVDTNIKNFYISLPGRIGTLISSQGMVAISSDDNEITKKDVNRVKRATQIINVPNDKEIVDIIPKEYIVDGYSNIKEPIGMSGNRMELDAYLVLAETTIVNNLLKTVQKAGYNILGVVFAPMADAKAALKEEEMNQGSALVNVGADSMDISIYKDGILAQTDTVSIGGNSITNDISICLKIPFSEAEKLKIKYGVIGENNLDLEGQIKVNIGYNNDITINAETLTKVVEARVEELLVLIQKRLKESGQFQDISNIVIVGGGLSLIKGIEELGKYIFNKNFRVGSPEYVGAANPIYVSSVGVVKSLFTPGKIQNVNLKNKEAAITKEDTSHYKVENEGKGVLLKIKEFLTEFF