lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the SKI complex involved in 3'-mRNA degradation pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKPALKAAKEALVVKNYELAIEQSKKALSFDANNYNANVFLGVAYFSTKQLSESKEAYLDAIKIDEKAVLAWQGLWNLYESTHDISELHKITPILASKFLELEEQNKCLNTVNKYMEVVKKYGNKADEFKALKLLTPEEGEIYEYLEGRVLPLQTVYMQMVDIQESMDRCYFESEVNKRKTRLGARLEQVMRDVELEIYKDSPLETLYNQIINYAETDEIRRLTESKLLHMYNKLLILSEIKEKSHWRERIWDLIQGMVTLHIPEQAAWTIYFEWQDHSDISFFQSAELQEYIELFPGSPLAQALFAFRNSDLWHKEHPIQLEDSNNSAELAKETKEEDDSENSVDKKENEEDIISSTMMPQDEVLANLTEAYENAPQSTIISECLAKYYIHLKEYEYAIGLSKAALEVLKRLQQDTGVKLDKLTRIFQLCLAIGYSHYEVPRYLFQAMHYYDILLAADPRNYHALLGKGLVQIENEQYSDAVKTLGLLLDDHENDPSLSELSWCYFKTGNLPKAISTVEKCLDVLLSMDVERFKIAEAYYRYGIYILNRKSENYLEDSFSAFVSSLRKDPNYAPAYTSLGLYYRDIHDMVRATKCFQKAFELDASQVEAAEALAKTFAEANEWELVEVISRRVLNTSENDLKRKKKFNWHHTSLGVLELNAKNFHKAIVHFQSALRISPKDTNAWSGLGEAYARSGRYVSALKAFNRASILDPDDWYVKYFIATLEKDMGEYEVAVSTLSEILAVRSKELCVQVSLAETYVRLAKLYHARGFYSRAADSLEKSIQICCNVLKEDITSIFSWEILGDACLSFCQLKNYHNRFPNSLISDILFTTEAMKCANNGRQFENMIYLPDLETSSGAIFIAAVAITCFTIHLSLVADDKLLLPVSWYNLGSSYYRFYECDTTKDATLQVAINCIKQAIKLEAKNYVFWNMLGVLFSQTKAVRSAQHCYIQSLLLNERSSGVWANYGALCIQNHDVECANAAFTRSISIDPDNSQAWLGKAYCSIAVGSIRKAVQIIHHAFEISSGKMPDVNYWYADTMLHAVNTEDFVTTDGDIWSATYAIKRYLGENPTDTFAYYIKASLLEHLGETTDSVPSAIRLCELLEQEYDVSESPVILKRFIDAKALLGRLYLAKKSFENSVEQAGIALDLLEGEEDEDIKRTTLGLNLTCGTASFFLNKLEKSLDCFEKALLVSDSNADVVVLVSKVLWALGSENGKQAAREQLFEALEQSPSHIGSLLCLGAIAIYDEDDAVCSAIEDSIAHLKKDEVLRSGALKQVQIMEVLLTKKIDESMIKSLLQRFLHVYPFAASSWTLLTNRYASKSLANAFATTLYTHPSRPDDLAQSYRLQNSIDRAQVAIHLVPWDSANWKALHGVTHEALVSSDAS
The following text describes a protein:
Function:
Exhibits fusogenic activity. Mediates cell-cell fusion in mammalian cells (bilateral fusion).
Subcellular Localization:
Cell surface. Cell membrane; Multi-pass membrane protein.
Domain:
The extracellular N-terminus has 4 domains; the first 3 are structurally similar to fusogens from plants, C.elegans and viruses, while the fourth domain is unique to archaea. Domains I and II are discontinuous. The fusion loop in domain II is stabilized by a Ca(2+) ion so that it protrudes from the molecule.
Sequence:
MKNGLKASVVALFFLLAASSASAATNSVDTVTYESNSDFFDGQVLQVGYTSNFATDKINVYLSESKIESETGAVADEPITFDVSHQNTYAKYPTQDTGLESITGWDAVKKTVSSKQELWDWTTTNCVDTNDAGTFTVDGYGTTDVDARANRWFDTWTGQYKYTIYCWQRNDYYGAVADIGSPDEVFRTEWRLQAGDKNPQTAVITNGDGGTGVTSNLGRYAKVSWEGSLSTGENPPLVDDEYALHSNDYEGGWRVISESRYSSYQSFVQNNADDLLGEWGAGLTTESHIESEMNGKAEEAASEFTESPLSDSEILDSSFQNGAFKLDMERSLMYPEFSVYVDAGENGYATISKPVGKPEIVSTSGAEFGELGQGTISVEAENVGDSEGSFSARTDSCGEYFSGNSLQDTQRVSPGGTASFDFRVTFTSTSMTQSEFSDQCEVVVEDTGSGNEVSASVSVTATQEDECTEGDETKKEKQVNGETVDVIMSCTNGLKLEEDEVCSADEEARYIDDDVQYECRDKDSPPGGGGGDPWTIPGLGWQLDTPFGGMEKALSGNAGALTWAQLLLSFIGFLAGFALVGVKLGKMVDGLATEFIPLSDAVVRLGIGLVGGGMAFMAVYQLVTNPLGFLLTVVGLLLTGYLYLKGTTPDINL
The following text describes a protein:
Function:
Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.
Subcellular Localization:
Cytoplasm.
Sequence:
MRSSTAAVQRPAAGDPEPRRPAGWAARRSLPRTARRGGRGGAVAYPSAGPPPRGPGAPPRGPRSPPCASDCFGSNGHGASRPGSRRLLGVCGPPRPFVVVLLALAPAATPARACPPGVRASPPRSGVSSSARPAPGCPRPACEPVYGPLTMSLKPQPQPPAPATGRKPGGGLLSSPGAAPASAAVTSASVVPAPAAPVASSSAAAGGGRPGLGRGRNSSKGLPQPTISFDGIYANVRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESVLFKCSDFVVVQFKDTDSSYARRDAFTDSALSAKVNGEHKEKDLEPWDAGELTASEELELENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNCSDREGHGPNTRDNKYIPPGQRNREVLSWGSGRQSSPRMGQPGPGSMPSRAASHTSDFNPNAGSDQRVVNGGVPWPSPCPSHSSRPPSRYQSGPNSLPPRAATHTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSMSSGLEFVSHNPPSEAAAPPVARTSPAGGTWSSVVSGVPRLSPKTHRPRSPRQSSIGNSPSGPVLASPQAGIIPAEAVSMPVPAASPTPASPASNRALTPSIEAKDSRLQDQRQNSPAGSKENVKASETSPSFSKADNKGMSPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLSKNREGEKSRDLIKDKTEASAKDSFIDSSSSSSNCTSGSSKTNSPSISPSMLSNAEHKRGPEVTSQGVQTSSPACKQEKDDREEKKDTTEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPAPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGKVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPAHAQPGLVSSSAAQFGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNAALHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQSSFPAAQQTVFTIHPSHVQPAYTTPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGPKAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL
The following text describes a protein:
Function:
Binds carbohydrates. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins. Can bind and deglycosylate O-glycosylated peptides from mammals.
Miscellaneous:
MISCELLANEOUS: Metal-binding observed in X-ray crystal structures is artifactual.
Sequence:
MKRKMLKRLLTSAFACMFIANGLITTTVRAVGPKTGEENQVLVPNLNPTPENLEVVGDGFKITSSINLVGEEEADENAVNALREFLTANNIEINSENDPNSTTLIIGEVDDDIPELDEALNGTTAENLKEEGYALVSNDGKIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVSARGIVEGFYGTPWTHQDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPESEMQRMQELINASAENKVDFVFGISPGIDIRFDGDAGEEDFNHLITKAESLYDMGVRSFAIYWDDIQDKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTGAMVSNGQPRAYTRIFAETVDPSIEVMWTGPGVVTNEIPLSDAQLISGIYNRNMAVWWNYPVTDYFKGKLALGPMHGLDKGLNQYVDFFTVNPMEHAELSKISIHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFANHSTRMDNKTWAKSGREDAPELRAKMDELWNKLSSKEDASALIEELYGEFARMEEACNNLKANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKEIAQNKLNTALSSFAVISEKVAQSFIQEALSFDLTLINPRTVKITASSEETSGENAPASFASDGDMNTFWHSKWSSPAHEGPHHLTLELDNVYEINKVKYAPRQDSKNGRITGYKVSVSLDGENFTEVKTGTLEDNAAIKFIEFDSVDAKYVRLDVTDSVSDQANGRGKFATAAEVNVHGKLKENAEVTGSVSLEALEEVQVGENLEVGVGIDELVNAEAFAYDFTLNYDENAFEYVEAISDDGVFVNAKKIEDGKVRVLVSSLTGEPLPAKEVLAKVVLRAEAKAEGSNLSVTNSSVGDGEGLVHEIAGTEKTVNIIEGTSPEIVVNPVRDFKASEINKKNVTVTWTEPETTEGLEGYILYKDGKKVAEIGKDETSYTFKKLNRHTIYNFKIAAKYSNGEVSSKESLTLRTAR
The following text describes a protein:
Function:
Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.
Subcellular Localization:
Dynein axonemal particle.
Sequence:
MAAVVRRMGPVWWGLTPALDLQMHCLPEATENLSCSDDLPELNILLVGGGDGRHILKTICQASRWPHRKLKFFIIESDLELLARHMLFLSLALEHPEQMGLQEKSELFLELFGNSLIRNKTASYLQEKSELFIRYVTDPDYQQSNVPLLNLSSIKFKERDKLEDIFKFWRNADPKLFPIDKYWDEKNRQNLGRRYDSRKGAYDWDLSMKLHDRGAGVINSREYNYWREKGVAFMNREGVYDIPNKTLASQMVVPQSSGKVLARGYWGDITASPYIAFGIETEEESLLQTANGVHVKSAQDIAQHNMISLFHELAYGKIYSVPASGQAESELAKTDSDYKTNEEQTVVETTEREAEDGDTNQSKCNRLITLNNVEIHFLPLSWVNELHCRFNNFFNLLYFSCSMVHFLKPEYKFIAASKATLVLELTKFMVDLQTEKLQDYVTIVAKLAQEAGFTPTETIDWKTDYIAKFERAHDSVEVQTGQ
The following text describes a protein:
Function:
Phosphatase involved in elongation process, probably by acting as a regulator of brassinolide signaling.
Subcellular Localization:
Nucleus.
Sequence:
MDLDSSMVPENDQDPIATSENQSPMEEKEEASEQQTGSESESASLTPSLPPPSQQQQQQQQQPQVTAVVGPRCAPTYSVVNAIIEKKEDGPGPRCGHTLTAVPAVGEEGTSSYIGPRLILFGGATALEGNSGGTGTPTSAGSAGIRLAGATADVHCYDVLSNKWSRLTPYGEPPSPRAAHVATAVGTMVVIQGGIGPAGLSAEDLHVLDLTQQRPRWHRVVVQGPGPGPRYGHVMALVGQRYLMAIGGNDGKRPLADVWALDTAAKPYEWRKLEPEGEGPPPCMYATASARSDGLLLLCGGRDANSVPLASAYGLAKHRDGRWEWAIAPGVSPSARYQHAAVFVNARLHVSGGALGGGRMVEDSSSVAVLDTAAGVWCDTKSVVTSPRTGRYSADAAGGDASVELTRRCRHAAAAVGDLIFIYGGLRGGVLLDDLLVAEDLAAAETTSAASHAAAAAAATNTPPGRSPGRYGFSDERTGELPESAPDAVVLGSPVAPPVNGDMYTDISTENAMVPGIRRTSKGVEYLVEASAAEAEAISATLAAAKARQVNGEVELPDRDRGAEATPSGKPSLSLIKPDSAVPNSVIPAGVRLHHRAVVVAAETGGALGGMVRQLSIDQFENEGRRVSYGTPESATAARKLLDRQMSINSVPKKVVAHLLKPRGWKPPVRRQFFLDCNEIADLCDSAERIFSSEPTVLQLKAPIKIFGDLHGQFGDLMRLFDEYGSPSTAGDISYIDYLFLGDYVDRGQHSLETITLLLALKVEYQHNVHLIRGNHEAADINALFGFRIECIERMGERDGIWVWHRINRLFNWLPLAALIEKKIICMHGGIGRSINHVEQIENIQRPITMEAGSIVLMDLLWSDPTENDSVEGLRPNARGPGLVTFGPDRVMEFCNNNDLQLIVRAHECVMDGFERFAQGHLITLFSATNYCGTANNAGAILVLGRDLVVVPKLIHPLPPAITSPETSPERHIEDTWMQELNVNRPPTPTRGRPQNPNDRGSLAWI
The following text describes a protein:
Function:
Voltage-gated potassium channel that opens in response to the voltage difference across the membrane and through which potassium ions pass in accordance with their electrochemical gradient. The mechanism is time-dependent and inactivation is slow (By similarity). Plays an important role in the rapid repolarization of fast-firing brain neurons (By similarity). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well (By similarity). Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Presynaptic cell membrane. Note=Localizes in parallel fiber membranes, distributed on the perisynaptic and extrasynaptic membranes away from the active zones.
Domain:
The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position; The N-terminal cytoplasmic T1 domain is involved but not required for Zn(2+)-mediated tetramerization.
Sequence:
MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGRKPLRGMSI
The following text describes a protein:
Function:
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Sequence:
MKRLYTTISSNKKKGKLASERHRSVSLPSETARPKHLSGSMTASEFEQLLRPFKASPTSESLINFSNSNEHTTCEAHSDKMYVVKRNGSREPVTIDKISKRLDILAKTPFAFYDTASRNEPGKYVVDDDLLATGRELKHAQPIRVAQKVCAALVDGITTEELDNEAAKQAAHMQTTHPEYGVLASRIEVSNIHKITPATFAGAVRRLQDRLDPLLFELVTTTDLGDRLEEAIDYKRDYCYDYFGLCTLQKMYLLKSKDGKIVERPQHMLMRIALWMHMSPDGAVDVPAVLETYRLLSGRFYTHATPTIFNAGTKMPQLASCFVKGTKVFTLEGPKPIETVRIGDMVITHEGRAREVSQLHKNHRGDRKILALKISGSPLLHVTENHKFLTLRDGLGEPAWSAADELKIGDYIQLPNYVGEKELPEPIDVWAILREAEPRLRYGTEEHVQDANSQIDEYVATADLRYCPPRNSATFAIRPRSIEVTEMFCKLLGMWLGDGHVLRGKVKGDDRTCYAGIGFNRSEDERVAQYVRQAGAKTFGVLAKPHGTCVEFYSGSLALVFEYLFGGVSAAKKLPPGVFTWPNDHIRALMEGLVISSGRVKGIEGVAIRTPNGTLMDQLFHLLRSRGVEVFLSTSKAHSYVTRRGDEIIVPTYDLRLPPDFLDLATIAVLRPDVETSAARPITGHSVRRQGSTFLRVVFVEVTDRDDPIVYNLGVDEDHSYMVEGVVASNCFLLGKLGNRAQDSVAGMYETLGHMASISKLAGGIGVHMHEIRATGAYINGTGGTSSGLIPYLRVHADVEDFLEIRLNVGAEDRRARDLFSALWVPDLFFKRVLEDGKWSLFCPSEAPGLSDVYGEEFEALYASYEAQGRARKVISARDLWEKVLVSIIETGTPYISAKDAVNRKSNQKNLGTIKSSNLCNEVTLFSNPAETAVCTLASIALSKFVKYGEEGRYFDFEELHSVVKTVTKVLDGVVDRTLYPQPECERSNKRHRPLGLGVQGFADVLYALHTPFESKKAAELNVRIFETMYHAALEASVELADRFGPYESFLGSPASEGLLQFDLWGVDPGDEYYDWAELKERIKSVGLRNSTLIALMPTASTSQLLQNTESFEIPTSMLYSRRTKAGQHIVLNRWLVRELLERGLWSVALKDKILADGGSVQNLDELDADLKELFKTTWEVKMKSYIDLSANRGPFVCQSASMNLYQQQPIADKLNRMLIYGWQMGLKTILYYLRTRSASEATQFTVAVDGKAKAEEPVLACTRDNKDCVACSA
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MTVLSAVISTKSKILVSRQFRNISKCDLDSLTIPFHNLIERERSDHTYIETDKVRYVYQPLDNIYIFLITNINSNIIEDLEIIKVLSQIIQDICQGNINESTILKKCFTIIFYIDELIKNGVREIVNSNQIKTYIEMESHEEKLQTIIRENKEKEEKERRKFIASKLEKNRQKQSKVSSNSFLSNDLINNLEYTNNIDMYKTEEQDIIDESFNTYKGMQLTSNKKENIRILNVVEHKVDTKPHINVNSIFDKPINIIITENIICTLSSEGTLCDLDIQGTFNLQINNHNYSKVIVELDNEYSEKAKIHPILDKNKYNSNILELKDKSKNFRINTIYPLLKWKINHINDSYIPLNISCWPCEDNESTLLSLEIENKRNNNDELIYDLNVNLMCPSAHKPQIISNDKGIIEHDGVLLAWKVDELKNNQSCQIEMSIQANPESVFPFSVEAKSNMLAHKLNVLKVYDEDTKKDIEYEIKKNITYLFTINK
The following text describes a protein:
Function:
May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDLEVSKGVRDIPGSLQSATSSMPSGKALMYFGLLLASGVFFIFIAFTMFLPVMVLMPQKFAICFTLGCGFIIGSFFALRGPKNQLAHMSSMERLPSTLGFIATMVGTIYVSMVLHSYILSVLFSVLQVLALVYYCISYFPGGSSGMRFLSSALTSSALRVFGR
The following text describes a protein:
Function:
Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).
Subcellular Localization:
Nucleus.
Sequence:
MGGRTVVSDDEEDDFVDGEEEEPRPARRGRDDIDEQDDDEEEEEDEEEEGENEYEKDGFIVDDADEEEEEDEQRASDDERRKKKKKKKRESEEFMLDEDDYMLLQDNNITGITRPKPANKFKRLKKAGREFEMGDHSGFSDDDGSGKRHTDEEKVKYSLFGQHDPFEEDIVEEEDQQAEEDEVGEDDMDDEMADFIVDEEEIDGNGQVVKRKKVKRKPLRQAAGVSSSALQEAHDIFGDVDELLALRKQELERDAFNSGELRGNRLEDEFEPFILAEKYMTAKDEQIKENDVPERIQLSEELTGNIRDDETKREEESVWIHNQLTGDGFLSFFGNEPVNREIQQKDIVNVLTMLHVNKFEIPFIAMYRKENCLSLLEDYDADEHENEEVPRKMRWHKLLWAVQTLDRKWLLLQKRKLALQIYYDKRFDDEKRRIDDVTRQSLNRQLYHSIIEALKEAKSEKEVEDVDAKFNLHFPPGEVEEEGQFKRPKRKSLYSICHKAGLWEVANQFGRSAEQLGHHLTLTKIPEAGELDSGKDSPEDVAANFTCAMFETPQDVLRGARHMAAVEIGCEPIVRKHIRSIFMNKAVVSTSPTPEGNLIIDAYHQLSGFKWLEEKPLNKFVDAQWLLIQKAEEEKLLKVTIELPEGAKKELIAEARENYLSDCVSKSAQLWDEQRKMILDDAFLTFLLPSMVKESRSLLTAKAKSYLHMEYGKQLWDKVSVAPWKKKDADKKDADIDMDDESELRVMACCWGPGKPATTFVMLDSSGELVDVLYAGSISIRSQGVSEQQRKKNDQQRVLKFMTDHSPHVVCVGASNLNCRQLKDDIYEVIFKIVEDHPRDVNPQMENFSIVYGDESVPRLYENSRISSDQLPGQSAIVKRAVALGRYLQNPLAMVATLCGPGKEILSWKLHPLEHFLTPDEKYEIVEQVMVDATNQIGFDVNLAASHEWHFSTLQFVAGLGPRKASALQKELVREGSIFSRKELVKPLGRKVFMNASGFLRVRRSGAAAASAQIIDLLEDTRIHPESYALAKNLAKDVRSEDSNEVNEMDDDEQEMAIEHVRERPTLLRNLKIPEYMESISEEFRKRQTLVDIKMELLSGFSDWRTPYAEPSPDEEFWLLSGETEDNISDGRTVQVTVRNIQENRIICTFDSGLKAIVMGDNYSDDVAFDAESLQLHEGDVLTGKIKNVNKNRFIVYLTCKESDMKRRPFTRNNHDPFNHEKHIVPNKDDKARKEKELAKKLFKPRMIVHPHFQNLTAEEAMQFLGDKEPGEKVIRPSLKGPSFLTLTLKIFDGVFAHKEITESGKDHKDITSLLRLGKTLTIGNESFEDLDEVIDRYVDPLVGNLKSMLSYRKFRKGLKGEVDDALRAEKAENPMRIVYCFGISHEHPGTFVLSYIRSTNPHHEYVGLFPKGFRFRKRDFDSIDRLVSYFQKHIDKPPPDAGPPMRNVAAMVPMKNSSWASGGAGGANDGWRGDGDNDRDRPFSGRTGGRFDSRNSSGGRGRGRGRGRGNFGNDGGGDNSGGWTDNIGGGSGGWGTGGGSGGGDAGWGGGGGDSNRGGGWGAAAATSDGGDGGWGGAAPGGNGAAGNDDSGWGSAKKAAPAQDGWGGASGGW
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MSQTVGKTRLAYSRAWHLVDVGSDGRSLGRLASSIALILMGKNKPIYDPSTDCGDYVVAVGCHDLHTTGKKRFQKKYYTHTTRPGSLRSMTMDKMFEKWGGGEVLRRAVRGMLPKNRLRDKRLARLKTFEGVDHPYKDNIVRIGAPSNIGALPEVKAAFQEAKTSQ
The following text describes a protein:
Function:
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2.
Sequence:
MVRPLNCIVAVSQNMGIGKNGNLPWPPLRNEFQYFQRMTTVSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPKGAHFLAKSLDDALELIEDPELTNKVDVVWIVGGSSVYKEAMNKPGHVRLFVTRIMQEFESDAFFPEIDFEKYKLLPEYPGVPLDVQEEKGIKYKFEVYEKNN
The following text describes a protein:
Function:
Cell envelope protein involved in phase variation, confers opaque colony phenotype.
Subcellular Localization:
Secreted.
Sequence:
MNSMDKNQQSSQNELDLGLNQEPITPKKTIQPSSSILGKAKGLFAKKNHVQTNFQQRKEPTFGDSSTQENDPLIPSENLKKVQKPVLQTSSTEENISAVDEEISAENNADEPVEKAEKPILAQPEKWKILQVLPAKHRRLFMAIFVLVILLIIFFALKPSSDTVESFTQSNSNEVPVQFQSLDQSQPLETTILDNPPAQNQMAVEQANQSEFAPKAEEAANNTTAQNPLVENAPMQQNVVQSPSQMPNEMAAASVAPMQPAQAEQPKATVPVQPMKKAVEPQVAHKDTVKKEVKVAEKAQAPAKATEQNVAKTAGNAPIVEAKPVQAKKEKKVQIVDAKPVSKSTASRLSAKTLTVPKGVSLMQLFRDNQLNISDVNAMSKATGAGNVLSSFKSGDKVTVSVNNQGRVNEMRLSNGARFVRQSDGSYQYKK
The following text describes a protein:
Function:
Two-heme-containing cytochrome. Catalyzes ascorbate-dependent transmembrane ferric-chelate reduction (Probable).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAVPVLGGFPIFMVVRVLGFIIAALVLTWTVHYRGGLALSSDNKDHIFNVHPVMMVIGLILFNGEAMLAYKSVQGTKNLKKLVHLTLQLTAFILSLIGVWAALKFHIDKGIENFYSLHSWLGLACLFLFAFQWAAGFVTYWYPGGSRNSRASLMPWHVFLGISIYALALVTATTGILEKVTFLQVNQVITRYSTEAMLVNTMGVLILILGGFVILGVVTPVSGKDQVLTQ
The following text describes a protein:
Function:
Essential component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway. U1 snRNP is cotranscriptionally recruited to intron-containing genes. Required for U1 snRNP biogenesis.
Miscellaneous:
MISCELLANEOUS: Present with 1730 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MDKYTALIHDENFSTLTLNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNEYVLLRNLLEKIESSYSDNVENVDDFEIFWDYLQFKTFCQNSLYSSRYSDSQSNGLLNKELFDKVWKRLSCKEKKSGQEILLNNLVQFYSKDTVEFVEKNIFQKIIEFGWEYYLQNGMFWNCYCRLIYFDTSRSYLDKRQYIVRKIWPQIDKKFAQSVLPSLTEFCESYFPEEMDTLEEMFTEEP
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication.
Miscellaneous:
MISCELLANEOUS: Present with 2753 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MKFCLYCCHCYIVICGKATHYYKSSKATSNLKSSNRVLMRNPMSPSEQHSQHNSTLAASPFVSNVSAARTQQSLPTDAQNDRLQQPWNRTNTATSPYQSLANSPLIQKLQANIMTPHQPSANSNSNSNSITGNVVNDNNLLASMSKNSMFGSTIPSTLRKVSLQREYKDSVDGVVRDEDNDEDVHNNGDAAANANNDRESKLGHNGPLTTTTLTTTTTATQLDVSELSAIERLRLWRFDALMQHMYRTAEYIADKVYNISNDPDDAFWLGQVYYNNNQYVRAVELITRNNLDGVNILCRYLLGLSFVKLQRFDDALDVIGEYNPFSEDPSTTAANTMSNNGNNSNTSQPVTDGGIKMESSLCFLRGKIYFAQNNFNKARDAFREAILVDIKNFEAFEMLLSKNLLTPQEEWDLFDSLDFKEFGEDKEIMKNLYKINLSKYINTEDITKSNEILAKDYKLADNVDVVRSKVDICYTQCKFNECLELCETVLENDEFNTNILPAYIGCLYELSNKNKLFLLSHRLAETFPKSAITWFSVATYYMSLDRISEAQKYYSKSSILDPSFAAAWLGFAHTYALEGEQDQALTAYSTASRFFPGMHLPKLFLGMQFMAMNSLNLAESYFVLAYDICPNDPLVLNEMGVMYFKKNEFVKAKKYLKKALEVVKDLDPSSRTTISIQLNLGHTYRKLNENEIAIKCFRCVLEKNDKNSEIHCSLGYLYLKTKKLQKAIDHLHKSLYLKPNNSSATALLKNALELNVTLSLDASHPLIDKSNLMSQASKDKASLNKKRSSLTYDPVNMAKRLRTQKEIFDQNNKALRKGGHDSKTGSNNADDDFDADMELE
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLSKYCVRNEYSLADPELCRAADKDDPEALLEAVAMAGLVGLLRQLGDLAEFAAEIFHDLHEEVMATAARGHGLMARVKQLEAEVPSLEKAFFSQTHHSSFYSNGGIDWHPNLHSEQNLVTRGDLPRFIMDSYEECRGPPRLFLLDKFDVAGAGACLKRYTDPSFFKIEPTSSVTATIEVQREKRIRKVKLKKGARLRDGETPNAVPSHAKLHQLLLEERIENGYSNPARLVKLKKRQLNGPAVETRAGKSYMEKFLETPSPDHKMVCETSIFPLPVKQTSDDASEAGIKILEISSISPVKKSLGNKNTYSSPDEKELELKPFSQMDGGTNGDLVKVKEQISDGVADKKSSNHLMLPDEAELAIDEQKKIEGSLDGYQSDDVTSEVDNYMDALTTMESELETDNEFKPKSSFLNIQKAANTNDKEEHQLQAQFSDSQSFGDSSMSDDCSSFKQDRNEEHIKVEAQLSDSQSTGTSSSLDDNSSFKRDGNGQHIELQAHLSDSQSVESSSTSDKNFKKDRSYLPHSDSLTTAVENMQSEPILFTNTKYCEPEVEDAPSNQLPHNVEFQRTDCERFVMHDDAPVHEEDISDLGQASSDLTTSGLVLCSDLVSTSPVILPSDETPSDPAELNLRLDDDDADRTGLVESITSKPVSLSLGTDDAHPLGSSDKTSLDNLDDDDPYIHSDDLLQVPNDLELAHGDECSDHSEIKISQAESPNENPSKILVNRDIGSPVEDPVSPSMEELNLNSGAMLARDCQDSKDEDCTVATQLNSVARVPPVSCFTGELSSDSTHNNTLNGPGSAEIEVSYSDLQSKAEEIPKMVHDDKINGSTFSANSVEGDAHFKHPSPDNHVMVNDLVTENVQSEDQAVYSVPSVDSAENDVGVVTCPASSQICSPSMGLSDLEEPLLSSHSYQMEIKSNEVELTQIAMDTNAEKRKNQSAPLLDVTSSDVVNSSMSNITKLEEPLSTFADSPKKEMEVDEAVARDSLTELEEQKIVDQPEIASVDVQLNLNKLVPCDLPDSEICNNNQKSSPREKFQHDAFVDDAEMVPEFSGLDDRQSESLSYGQHDPLQNGRDSFSSSSGNQLEPETDLDLLSKSQIGEQDAEFPVRDEKNFASEKSQCQQMQICQLEQESTHATSECASEIHADEPSSFYSFPQSSSQENNAAKHVMDPLKPLLPNLFPKATENNLDEMPPMPPLPPMQWRMGKVQHASLASQREELEVSPASVQPIRPDKQSLFGLPTSERDALLYQNPFLPVMAVESDKLQDSSGFPVDVSGHPVAIPFQFPVMVNESKGQYNYLLLDRNQIQNPFLTLPVASTAMPPQGFFVAPEGEMIQNSNPCAPIPSAAYDVSGHNSIPPQEKPTQPPNQLMMETSPDDKSLLQSMSNMVSMDRPPHGHAVASEGEKVLNSPTIPPAECAVSGHDSVSPQEKLTQHPSQLLTEHSSDDKTLLQSVTNVVSMDSSDSQIVSSEGEMEQSSNPNPPSPPVECAVPGPGHDSISSHESLTLPPSQLMSETSSEFKTLQQSISNVEGEQGRLPISFMSPSNMESMEPNQSFPPFEGGMSASLDTSDHTSDVESERTNGKPKNKLPRPRNPLIDAVAAHDKSKLRKVTERVMPQIAPKVDERDSLLEQIRTKSFNLKPAVTTRPSIQGPKTNLKLAAILEKANAIRQALAGSDEDDDADWSDS
The following text describes a protein:
Function:
Plays a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power.
Subcellular Localization:
Plastid, chloroplast stroma. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=More abundant in the soluble fraction. The presence of LFNR1 is required for association with the thylakoid membrane.
Sequence:
MATTMNAAVSLTSSNSSSFPATSCAIAPERIRFTKGAFYYKSNNVVTGKRVFSIKAQITTETDTPTPAKKVEKVSKKNEEGVIVNRYRPKEPYTGKCLLNTKITADDAPGETWHMVFSHQGEIPYREGQSVGVIADGIDKNGKPHKVRLYSIASSALGDLGNSETVSLCVKRLVYTNDQGETVKGVCSNFLCDLAPGSDVKLTGPVGKEMLMPKDPNATVIMLATGTGIAPFRSFLWKMFFEKHDDYKFNGLAWLFLGVPTTSSLLYQEEFDKMKAKAPENFRVDYAISREQANDKGEKMYIQTRMAQYAAELWELLKKDNTFVYMCGLKGMEKGIDDIMVSLAANDGIDWFDYKKQLKKAEQWNVEVY
The following text describes a protein:
Function:
Mediates sugar transport across membranes.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MFTTPLLAGLEAHRERIGQAAGLLTVAQYLAGWFICSDIRRRGTSAGVSPLRFIGGCGLSILQLQYSEKLQAPALIWTSIFTLAFSLLYSLWFWWYTPPSGRGALYRLTAAVATVTAGLYAYGAQGDGPDVMYRLGMVLTVLALAFIALPLAQLRSIIRAKSSAGLPLPAILASTGATVLWLLYGLLINNTFIVVQKIIAMGLCTVQLSLFIIYPASTSSGGEKKKQ
The following text describes a protein:
Function:
Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Prefers Ala and hydrophobic residues at the P1 position, and has no preference for P2 residues. Shows the highest dipeptidyl peptidase activity toward the synthetic substrate Lys-Ala-methylcoumaryl-7-amide (Lys-Ala-MCA). Is likely involved in amino acid metabolism and bacterial growth/survival of asaccharolytic P.endodontalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources.
Subcellular Localization:
Periplasm.
Sequence:
MKRTILSLLAAVSLAIPVYAAGYSDGNPTQQTSQSSMMTPEMLLTMARIGGFSLSPNGKQVVYSVSLPSIQDNKAKTQLFFVNSDGSGRKALTDGTRTAVSPRWIEDGKRIAYLTVIEGEMQLVSILPDGTDQRQVTRIPGGITGYLYSQDGKQLVYTADIKLPNEAKDRNPDLDKISGRVITDLMYKHWDEWVETAPHTFVASLAQQPITQGKDLLEGELFEAPMKPHSDESDIAITPDGKGIAYASRKKTGLEYSISTNSDIYYYDLTTGTTTNLTEGMMGYDTHPSFSPDGKYMTWCSMERDGYESDLIRLFLLDRTTGEKTYLTEGFEYNVEQPTWSQDGKSIYFIACVEAESHLYELTLKNKKIRRITQGQMDYVGFDLQGTTLVAARQSMLAPTDLYRIDLKKGTATAITKENESTLAQLGDIRCEKRWMNTTNGEKMLVWVLYPANFDASKKYPSILYCQGGPQSTISQFWSYRWNPRIMAENGYIVILPNRHGVPGFGKAWNEQISGDYGGQNMRDYLTAADEMKKESYIDPNGMGCVGASYGGFSVYWLAGHHEKRFNCFIAHAGIFNLEAQYLETEEKWFANWDMGGAPWEKSNATAQRTFATSPHLFVDKWDTPILIIHGERDYRILASQGMMAFDAARMHGVPTEMLLYPDENHWVLQPQNAVLWQRTFFRWLDRWLKK