lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
Subcellular Localization:
Cytoplasm.
Sequence:
MAGKSKGARNKAKAQAASQEAVSVEPVADVAEEAKPQNGEVTEAPAAEVAPAAEVAAADVEKEEGDVAEAAQAAEKPAEAGELHLYPVSVKTQSGEKLELQLSPGDSVIDVKQFLLDAPETCFYTCYDLILHTKDGSTHQLEDYNEISEIADITAGGCSLEMVAATYDERSIRSHLRRVRELLSLSSLHVSLSTSLALQQESAQAKNADAGKTAHQELDGLNFMEDTTVALTNLLASAPAEIKCVDSIVFSSFNPPPSYRRLHGDLIYIDVVTLEGSKHCITGSSKSFYVNASNGSILDSRPLKQSHEASTLVGLLQKISAKFKKGFREILDRKASAHPFENVQALLPVTSWLGAHPVPEHRRDAARAEDSVVLSYGTELIGMQRDWNEELQSCREFPHANPQERILRGRALYKVTCDFVDAAVKGAVGVINRCIPPINPTDPECFHMYVHNNIFFSFAVDSDYEQISKDQKPDCQNGSGRSTPVPSPALGAKADSGVAPDSKTEESNSVLEGPTEAQIADSEQATYASANNDLKGTKSYQEADISGLYNLAMAIIDYRGHRVVAQSIIPGILQGDKSDSLLYGSVDNGKKISWNESFHAKVVEAAKRLHVKEHVVLDGSGNPVKLAATVECKGIVGSDDRHYILDLMRVTPRDSNYIGLQHRFCVLRPELVASFVEAESIKKSPTEKVPDAPTESNGQEPDDIASGSDATAASVEEHDKSDETPVSTPAESNDMTAEILFNPNVFTEYKLAGSPEEIEVDEALVKKVGSYLLDTVIPKFVQDLCSLDVSPMDGQTLTDVLHSNGINVRYLGKVAGMIKHLPHLWDLFSAEIIVRSAKHVVKDILRQSPDHNIAPAVAHFLNCFFGKVLAASSKGSTGSPQSKTQKKSSESASSKKGQSAFSQLTSDGVWSDIKEFAKHKYQFEAPDDVRVGTKRVAVLRNLCQKVGITIAARKYDLHSTTPFQPSDILNLQPVVKHSVPTCTDARKLMEAGKIRMAEGTLNEAYALFSEAFSLLQQINGPMHKDAANCCRYLAMVLYHAGDTAGAIVQQHRELIINERCLGLDHPDTAHSYGNMALFYHGLNQTELALRHMSRTLLLLSLASGPDHPDVAATLINVAMMYQDASNMSTALRYLQEALKKNERLLGPGHIQTAVCYHALAIAFSCMGAYKLSVQHETKTHDILVKQLGSDDSRTKDSENWLNTFKGREQQVIAQKQKGQGTVPSANAVEFLKAHPGLFQAMKAAAIQSGGDGPANVNRGRGGDERAAKAAAEARKTAVARGVNLRNGPAASVSDINQILNLINSAASASAASSGNAQATESEVPQSNGPALNGAKESKDTSRPSAKADGQAPVGLGASLELKKQKSKQKA
The following text describes a protein:
Function:
Involved in DNA repair and RecF pathway recombination.
Sequence:
MSLYKTRAVVIKTQEFKEADKLVWLYTEKLGKITAIAKGAKKNRSKYLSNTSPFCYGEYVLYKGKSLFNLSEVQLIDSFQDFLRDLDTLTYGSYFCELIDICTEEKESSRELFQELVKSLFLMKNKVVDIEILARAFEMKVLKYTGYALNFNHCVECGRKIETSNYISLQSLGGICNYCNKINGIGVTYATYNILKYIYAAPLEKLYRLSVDTETKKDIYKILNTIINQNYLKKPKSLQILNYIKEE
The following text describes a protein:
Function:
Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MQNLSPACTFNKNEEKIKCPSSTKLGCSDGTKIIQHEINERNMMPEIPNVSLTDENDFTFNKKRHVSSIPKNNNEYWVYPSSQQFYNSLIRKNKDIDKNYIDAVVSVHNEVNEESWKQILKYEHMHKRSCTDVTLHRFLGKFDDLSIKARFRSIFSSMGRPFDRHDWYVNRCGTQVKYILDYYNDESINDDKNIYIDVRPAMNSFSNVWDRLRYPFYEFYFKYVKKDELFK
The following text describes a protein:
Function:
Component of SCF(VBF) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins such as VIP1 and Agrobacterium virE2, after their implication in T-DNA translocation to the host nucleus (can functionally replace Agrobacterium VirF). Required during Agrobacterium-induced tumor formation.
Sequence:
MMMLPEACIANILAFTSPADAFSSSEVSSVFRLAGDSDFVWEKFLPSDYKSLISQSTDHHWNISSKKEIYRCLCDSLLIDNARKLFKINKFSGKISYVLSARDISITHSDHASYWSWSNVSDSRFSESAELIITDRLEIEGKIQTRVLSANTRYGAYLIVKVTKGAYGLDLVPAETSIKSKNGQISKSATYLCCLDEKKQQMKRLFYGNREERMAMTVEAVGGDGKRREPKCRDDGWMEIELGEFETREGEDDEVNMTLTEVKGYQLKGGILIDGIEVRPKT
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MPRPRTTSAYRLRRSTVPCVQSLGAFSHLIIATRTIVQSNVTGGVRSLLDQFETRTLITRLRRNRNGNYYRFRQKLWLSQEALEKELTEITYSPVERQPFALLPQREAPRQVFACEGRGGTLLLEEVQAEARRASASESSSTPAAASILPSQSERCDDNDSLDFMASLLQADQSVGSKIITEADVEGTVLESARFRARQILASDLTCNAVAVSPSTSVSLRKPAESTDAAGTSWSALGLDPLISSAAKQLYGPVPTRLQARLLPALLNEDHNDVLFNGVTGSGKTSALVLGLLQGIRSEAAGMNILVATNTMNAMRLHDTVKALCRRAGGGVVVDRPADDYSWLFLGTYREDYESYYEHLRRGLRRATGPARLFITTADVMCQLLFEKKMEFEDFGYLRRVYVDDIGAQVPLLPESAPVAVVRERLRNPLAAELLLGTLHQLPGPHVRSVLQLGMVSADVDGKLKDHLQALCMKPVAQTTVLSTVRIPSTVHCLFSFFLNDREDRFTYLARLLWNARETIPGRAVLFVPDAEDVLNARRRLRGLGADVKIFSEVHGGSEFKGDWKFLLLKESEAFGVDLPLVSHVFITFAPTSWQRFLHMCGRTGRMGNVGWVYVVSDKQDAKSVREVAEALSVDFCNHVISDDLQQVRPADVERFTKQPELYGLDPQFAVRQHYTVQAENPDMAYRKREFFSKPAMKQFQMEDYTPIPIKQRRFDHARQLSQDVERNPSIVLDMQKRGLLDAHLKPTKTLKRYMDLKTHREAPDPFQKERKRPQRR
The following text describes a protein:
Function:
Part of a binding-protein-dependent transport system for taurine.
Subcellular Localization:
Periplasm.
Sequence:
MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPAIIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFAKSAIDAQQPYIANPDVWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ
The following text describes a protein:
Function:
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane; Catalyzes the exchange of ADP and ATP across the membrane.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MYIYSSKYCVRRCQLLSHLLYHQSSPSSPRSSPLPSRFPRRVERRSLFSVAVADMNQHPTVFQKAANQLHLSSSLSRNVHTRYGSVQPALYQKQFAYGNYSNAGLQRCHATQDLSLITSNASPVFVQAPQEKGFAAFATDFLMGGVSAAVSKTAAAPIERVKLLIQNQDEMLKAGRLSEPYKGIGDCFGRTIKDEGFTSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGAAGASSLFFVYSLDYARTRLANDAKASKKGGERQFNGLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVLLTGSLQDSFFASFALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFSQIVRNEGAKSLFKGAGANILRAVAGAGVLAGYDKLQVIVFGKKYGSGGA
The following text describes a protein:
Function:
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
Sequence:
MRVRLLEATENPEELICQSARNDYMSDWVGDTPLDTAMASVDGDTTDEKLSNLIAQLLTRGHYGPFEHPSATFAIEGVSRSCMAQLTRHRHASFDVQSMRYVAFDDVDPAAVAEGELVVTPPSATDPDWVGRNQDAGDIDEETMAEREAVFQASVRRAVEDYQELLGLGMPPEDARFVLPIGTEVNVVITLNPRSLMHVADMRAAADAQWEIRELTEQLLDAAAQWCPHTFEYYDAEMKHRKNRLAP
The following text describes a protein:
Function:
Endoplasmic reticulum (ER)-bound sequence-specific transcription factor that directly binds DNA and activates transcription. Plays a role in the unfolded protein response (UPR), promoting cell survival versus ER stress-induced apoptotic cell death. Also involved in cell proliferation, migration and differentiation, tumor suppression and inflammatory gene expression. Acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration. Associates with chromatin to the HERPUD1 promoter. Also induces transcriptional activation of chemokine receptors. Functions as a negative transcriptional regulator in ligand-induced transcriptional activation of the glucocorticoid receptor NR3C1 by recruiting and activating histone deacetylases (HDAC1, HDAC2 and HDAC6). Also decreases the acetylation level of histone H4. Does not promote the chemotactic activity of leukocyte cells; [Processed cyclic AMP-responsive element-binding protein 3]: This is the transcriptionally active form that translocates to the nucleus and activates unfolded protein response (UPR) target genes during endoplasmic reticulum (ER) stress response. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3') and C/EBP sequences present in many promoters to activate transcription of the genes. Binds to the unfolded protein response element (UPRE) consensus sequences sites. Binds DNA to the 5'-CCAC[GA]-3'half of ERSE II (5'-ATTGG-N-CCACG-3').
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus. Nucleus. Cytoplasm. Note=Colocalizes with HCFC1 in neuronal cell bodies of the trigeminal ganglia. Colocalizes with DCSTAMP in the ER membrane of immature dendritic cell (DC). Colocalizes with CANX, CCR1, HCFC1 in the ER membrane; [Processed cyclic AMP-responsive element-binding protein 3]: Nucleus. Note=Upon RIP activation the transcriptional active processed cyclic AMP-responsive element-binding protein 3 form translocates into the nucleus. Detected in the nucleus upon dendritic cell maturation and RIP activation. Colocalizes with CREBRF in nuclear foci. Colocalizes with CREBZF in promyelocytic leukemia protein nuclear bodies (PML-NB).
Sequence:
MDPGGQDLLALDPGDQDLLGFLLEESGDLWAATEPDVKASLDLELSPSENSVQELSDWEVEDLLSSLLSPSVSRDVLGSSSSSILHDHNYSLPQEHVSIDLGECEMISCRGRRELTGLAGSTFPFADTESFEKEGFHVTPLPGEERAAEQEMSRLILTEEEKKLLEKEGLTLPSTLPLTKVEEQVLKRVRRKIRNKRAAQESRKKKKVYVVGLESRVLKYTAQNRELQNKVQRLEEQNLSLLDQLRKLQAMVIEIANKTSSGSTCVLVLVFSFCLLLVPAMYSSDARGSVPAEYVVLHRKLRALPSEDDHQPKPSALSSELPMDSTHQSLDSSEHMFLVSSNFSCVLYHAPQAEQPLHWPLWDLSSEMLFSDSNLLLQANLSESEGWQPNHSPSLVIFQGRYSG
The following text describes a protein:
Function:
Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export (By similarity). The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription (By similarity). THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase (By similarity). The THO complex is also required to maintain TRAMP complex occupancy at sites of snoRNA transcription thus promoting exosome-mediated degradation of snoRNA precursors.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEETAIRSRLTVEERPLKRLISRCLGFAAQNVDEANLRDLEIEFSALSAFWLRLQMQLDMNAKEVDVYEGELKKTQTFCEAEKTEISQLEQDLLVAQEELRKREQYDELAKPIMSKGLRSRTEQQESIGKLQDAIRELEEENANYVKAWNLRKDIFDETLKQMNHLQSILHPPSNPESDSEEGIASEGENPSSSSSTQYKAK
The following text describes a protein:
Function:
Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence CAC[GA]TG. Seems to activate the transcription of growth-related genes; required for cellular proliferation and growth. Functions in the TORC2-mediated regulation of cell growth, acting downstream of the TORC2 complex. Inhibits the demethylase activity of Lid. Activates transcription of mbm. Has a role in ribosome biogenesis and endoreplication in fat body cells by activating the transcription of LTV1. Able to induce the SCF E3 ubiquitin-protein ligase member archipelago (ago) which functions in its degradation. It may therefore create a negative feedback loop with ago that is regulated by the ubiquitin hydrolase puf. In dopaminergic neurons, regulates dopamine levels by binding to the E-box (E1) of the dopamine decarboxylase Ddc promoter and thereby inhibiting its transcription. This regulation is required to suppress male-male courtship. Involved in the acs and insulin signaling mediated non-cell-autonomous induction of amino acid release into the hemolymph following the cytoplasmic purge response to intestinal bacterial infection; required for efficient recovery of enterocyte thickness.
Subcellular Localization:
Nucleus. Nucleus, nucleolus. Cytoplasm. Note=Translocation from the cytoplasm to the nucleus may be promoted by the TORC2 complex (Lst8 and rictor). Localization to the nucleolus is dependent on Heatr1.
Sequence:
MALYRSDPYSIMDDQLFSNISIFDMDNDLYDMDKLLSSSTIQSDLEKIEDMESVFQDYDLEEDMKPEIRNIDCMWPAMSSCLTSGNGNGIESGNSAASSYSETGAVSLAMVSGSTNLYSAYQRSQTTDNTQSNQQHVVNSAENMPVIIKKELADLDYTVCQKRLRLSGGDKKSQIQDEVHLIPPGGSLLRKRNNQDIIRKSGELSGSDSIKYQRPDTPHSLTDEVAASEFRHNVDLRACVMGSNNISLTGNDSDVNYIKQISRELQNTGKDPLPVRYIPPINDVLDVLNQHSNSTGGQQQLNQQQLDEQQQAIDIATGRNTVDSPPTTGSDSDSDDGEPLNFDLRHHRTSKSGSNASITTNNNNSNNKNNKLKNNSNGMLHMMHITDHSYTRCNDMVDDGPNLETPSDSDEEIDVVSYTDKKLPTNPSCHLMGALQFQMAHKISIDHMKQKPRYNNFNLPYTPASSSPVKSVANSRYPSPSSTPYQNCSSASPSYSPLSVDSSNVSSSSSSSSSQSSFTTSSSNKGRKRSSLKDPGLLISSSSVYLPGVNNKVTHSSMMSKKSRGKKVVGTSSGNTSPISSGQDVDAMDRNWQRRSGGIATSTSSNSSVHRKDFVLGFDEADTIEKRNQHNDMERQRRIGLKNLFEALKKQIPTIRDKERAPKVNILREAAKLCIQLTQEEKELSMQRQLLSLQLKQRQDTLASYQMELNESRSVSG
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8 in vitro.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.
Sequence:
MSANELPASAQSLQEQFLGSFVTRKLLLHDPFDHNSLRVFAVAPSPLITHENNLKGNVLMLLSVLICGIICCLGLHYIIRCAFRRSSRFMISEPISSLSTPRSSSNKGIKKKALRMFPVVSYSREMNLPGIGEECVICLSDFVSGEQLRLLPKCNHGFHVRCIDKWLQHHLTCPKCRHCLVETCQKILGDFSQADSMASTPTESVIVRIDPLEPEGRVNTFRESS
The following text describes a protein:
Function:
Inhibits bovine trypsin with a Ki of 0.174 nM and trypsin-like proteases from G.mellonella larvae. Has no activity against serine proteases chymotrypsin, subtilisin and elastase. Has no activity against cysteine proteases from beetle gut.
Sequence:
SEKPQQELEECQNVCRMKRWSTEMVHRCEKKCEEKFERQQR
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MGKKAKKKARTPPAKENLNQTKNLSEQPSEVAEGQVKEKQACVHFDKGLNLDKVLEKIKSSRVIKCHECKEGAKGKGSNKGKHKAIWVCLECGCYVCGGVGLPTLPQSHVLKHIRMTRHRLVIQWENPQLRWCFPCNSLLPSERSLNSLAPSSSDDAQGSGSITTDIKLESDGYVVRGLVNLGNTCFFNSIMQNLLSLDQLRSHFLKDDVSGFGLPLASSLRKLFAEMKPEAGLKSVVNPRAFFATFCAKAPQFRGYDQHDSHELLRCLLDSLSTEESAWRKRRGGVCDDDEKATTTATLVESVFGGETSSIVSCIECGHSSKIYEPFLDLSLPVPFKKTPPKKQQALSRAKKADSDNGAVSETPSVITLDNKEASENVAQSDTVFDSFWLDVIAPEPAGDETNLDMEDSVSDKTPTPEAISLGDQASEGNAERLIQDSDEFAKADEKDVQATQSDECTATSAISAEISQDSCIGLDPGLGESSSSVNPWDEEEVPLMVADSQVLYMPYKENVSSYDEGEASSSFVSGDNQEPENNDFVGLGGLFDEPEVTEGPVVFGPPCKPEASSGVVGFMAFSSESDPEEIDDSDSPVSVERCLAHFTKPEILSDDNAWNCENCSKNLKLQRLREKRKSSNTSSNGWVSENEDGVLGETDVKQDPSDSGREAMSSNDSESEGEEDSKKVITVKRDATKRVLLNKVPPVLTIHLKRFSQDLRGRLSKLNGHVAFKEVIDLRHYMDPRCSGEDPPVYRLAGLVEHSGTMRGGHYVAYVRGGGGKKVKESDSSSSSVWYNVSDAHVRQVSLDKVLHSEAYILFYERIV
The following text describes a protein:
Function:
Might have a systemic role in water and solute homeostasis.
Subcellular Localization:
Secreted.
Sequence:
MSKSIVFFSTVLVFLFSFSYATPGIATFYTSYTPCYRGTQEGVMIAAASDTLWDNGRVCGKMFTVKCSGPRNAVPHPCTGKSVKVKIVDHCPSGCASTLDLSREAFAQIANPVAGIINIDYFP
The following text describes a protein:
Function:
Involved in global genome repair (GGR) via nucleotide excision repair (NER), in conjunction with rhp16, after UV irradiation.
Subcellular Localization:
Nucleus.
Sequence:
MSSGSRVRGPNSALTEFLRSQGINASALGRARPPRQSEESAGQSTGTESEVIQTPTSVEENNEDENSMSTTTIEIPVVKRRNLRNQKKKKKTDEEAEDNEDTFSMNSRAGFSYKAREHTGKLDFCAHCNCRFTITPYSKYSNSEKGWLCYPCSRGAEDRSVPELRTRKRKALTRKKVAAATMDEEISVPKLQDLCIRVIAEYINDIEAFGDIGQVNMDKISQIISKNRSLNDTTVKLFLSGGQTELKLYDCSKITADSLFQIAQYCPNLQTLHLTYCGQMQDQVLHFYADHLTELTDVSFQGAFLVSSSEWINFFKKRGSKLISLELTDTARIHVSVINAIVDCCPNLISLNLSRIFYLDDECVRLLAGCRNLVSLKIESPGGIINDGSILDVLNQIGSGLHTLSLSGCTKLTDEVLKQGIGPCCGRLKHLNLSGLELLTDDEASIVFGEWKIQSGLETLSLRRCLSLGDKTVRAVLVNSGHTLRTLDLNGMSFVTDEALQYIVNFPLPMLKALDVSWIRGMNDKLVCDFESKKPTLEKLLVWGDNHVLMPSNRLLLIGREVQ
The following text describes a protein:
Function:
Possible transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MAQHDFVPAWLNFSTPQSAKSPTATFEKHGEHLPRGEGRFGVSRRRHNSSDGFFNNGPLRTAGDSWHQPSLFRHDSVDSGVSKGAYAGITGNPSGWHSSSRGHDGMSQRSGGGTGNHRHWNGSFHSRKGCAFQEKPPMEIREEKKEDKVEKLQFEEEDFPSLNPEAGKQHQPCRPIGTPSGVWENPPSAKQPSKMLVIKKVSKEDPAAAFSAAFTSPGSHHANGNKLSSVVPSVYKNLVPKPVPPPSKPNAWKANRMEHKSGSLSSSRESAFTSPISVTKPVVLASGAALSSPKESPSSTTPPIEISSSRLTKLTRRTTDRKSEFLKTLKDDRNGDFSENRDCDKLEDLEDNSTPEPKENGEEGCHQNGLALPVVEEGEVLSHSLEAEHRLLKAMGWQEYPENDENCLPLTEDELKEFHMKTEQLRRNGFGKNGFLQSRSSSLFSPWRSTCKAEFEDSDTETSSSETSDDDAWK
The following text describes a protein:
Function:
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKEDVIEMQGTVLDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVEMTPYDLSKGRIVFRAR
The following text describes a protein:
Function:
May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 and RND3. Promotes RHOA activation mediated by GNA12 and GNA13.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MELMSSMMQKISLLEQKIDKQAQEIQLKDRKIAELEEKMKTLQKGEDAPDSSTAEDLETRCLQLQTQVWEMERFLNDYGLVWVGDRHEEQEDLESLRDDELLAKRKPGEAVVSKHQVDFDLILENVKSLNMLAGDCISHIEHTPGGARLRQPEPLPLTLYQNGIVMLDGPFRSYEELSVQQCLQDIMDGYFPSELQARYPDGVPLQVTDKRDVVFQERDLPGSFPGHGQVVGHSKLSKVEEPAKIPGPKPSLEQFWNKYSKSSMHSEAMATRDTVGAMQQGSDGVWSSKEIVVGTPRLSVLQRLETSEEAEASAPDVCTLRIKSESGEQMYVIKMLSSETIGDLRQHLAHARGGDSDSYEIISTFPQRVYADNSRSLQECGLIPNASLLLRRRDPFPPEGTALQTA
The following text describes a protein:
Function:
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
Subcellular Localization:
Nucleus.
Sequence:
MNAERCEFIAGNSLIEVIPSISDDRPIHLISGDIGPFEAGVPCRIPVWTAILMKRKHNCKVVAPQWMDVDELKKILTSETESQGLAKLPDHFFEISHMLVRDAREDIFEVEAVKSLVQDIYDRRDAKLRSSAIEFLRQNQTCHAQLDNVQLIEASSARATLEACRQMGAVVRNKHESTPL
The following text describes a protein:
Function:
Deubiquitinating enzyme that may function as negative regulator of the innate immune system. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro) (By similarity).
Sequence:
MTILPKKKPPPPPDPEANGERSGSGAPDSHSRSGARPRSSPPPRWAYPGNPSSAAERHTQQVSPPPGSATSGGAGPLGDGALGSCCCCNGAGAGGCCSGPGHSKRRRQVLSAGPGATGNCPDTDDGAGNNSEDEYETAAQTQHLDPDTAEQQELCFEKTLSDKKGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQYGTEPINTFHGIQKNEDEPIRVSYHRNIHYNSVVNPNKATIGVGLGLPSFKPGYAEQSLMKSAIRTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQARQPRKASATCSSATAAACSGLEEWSGRSPRQRSTAGSPEHPDLHAELCMKPPSPGAPLILGKPPSPCAPGPSNQMSTGADRATSPLVSLYPALECRAIMQHMSPTAFGLKDWDNDEILASVLAASQQEYLDTMKKSTLRRESSPDHS
The following text describes a protein:
Function:
Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSLPCKTILASTIAKPFTEEVENGVSQLGRKPRLVGFLANNDPAAKMYADWTGKTSESLGFEYDLRVLDKEDLEEAIVTANNDDEVDGMMVYFPVFGPGQDSYIQQLMSPDKDVEGLSHIFIKNLYHNVRFLDAPEDRQKSILPCTPLAIVKILEHLGVYNAVLPYGNRLYGKTVTVVNRSEIVGRPLAALLANDGAIVYSCDITGIQKFTRGEGLSLKRHNVEDVKDMDIQKCAAVSDVIITGVPSASYKFPTEWVRYGAVCINFSSEKNFDPSVKERAALYVPSIGKVTISMLLRNLLRLINNKVIRQEEIKEKEAKKAKVEE
The following text describes a protein:
Function:
Endosperm-specific cysteine-rich protein that acts downstream of BHLH95/ZOU to modify the interface between embryo and endosperm and mediate the separation of these two tissues during seed development. Necessary for the biogenesis of the embryo sheath, an extracuticular endosperm-derived structure at the surface of the embryo. Required for the separation of embryo and endosperm, and for normal progression of the embryo through the endosperm tissue. Required for the formation of a normal embryonic cuticle.
Subcellular Localization:
Secreted.
Sequence:
MMSIKLTLCALIFFLLNSLLHHVLGHDNQLNTTSSWLKSHIKAATTTNWGRPKPPMCKPWICKRSGPSEARMRCCRNQCVDVLSDPNHCRFCFKSCRFALSCCDGDCVDTNTDPSNCGQCGNECESGAPCEFGMCGYAAPSSQPGKRHRRHKFHRPRPPPSPDSKLNYDDHDDE
The following text describes a protein:
Function:
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
Subcellular Localization:
Nucleus.
Sequence:
MELELGLAPPNSGHLVVDELSSSSSSGGGSGSAPVSASSAGKRGFREAFQETLLLFDDGSCCNTSDDDCRRRKKTVVGWPPVSSARRACGGANYVKVKKEGDAIGRKVDLALHSSYDELAATLARMFPTNDHQGEKKMANDDHGDAAGPVVTYEDGDGDWMLVGDVPWDDFARSVKRLKILG
The following text describes a protein:
Function:
Component of the yop secretion machinery. May have a role in the negative pathway regulation of yop expression controlled by calcium.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIQLPDEINLIIVLSLLTLLPLISVMATSFVKFAVVFSLLRNALGVQQIPPNMAMYGLAIILSLYVMAPVGFATQDYLQANEVSLTNIESVEKFFDEGLAPYRMFLKQHIQAQEYSFFVDSTKQLWPKQYADRLESDSLFILLPAFTVSELTRAFEIGFLIYLPFIVIDLVISNILLAMGMMMVSPMTISLPFKLLLFVLLDGWTRLTHGLVISYGG
The following text describes a protein:
Function:
Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination.
Sequence:
MNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASDLVSRKNVEYLVVEAAGETRELRLDKITSFSHPEIGTVVVSES
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.
Sequence:
MSMTEETKTTKLESAGDSSDVDNGNCSSSGSGGDTKKTCVDCGTSRTPLWRGGPAGPKSLCNACGIKSRKKRQAALGIRQDDIKIKSKSNNNLGLESRNVKTGKGEPVNVKIAKCEPGIVKIAKGEPGNVKNKIKRDPENSSSSNNNKKNVKRVGRFLDFGFKVPAMKRSAVEKKRLWRKLGEEERAAVLLMALSCG
The following text describes a protein:
Function:
MRS4 suppresses a mitochondrial splice defect in the first intron of the COB gene. It may act as a carrier, exerting its suppressor activity via modulation of solute concentrations in the mitochondrion (possibly of cations). Not essential.
Miscellaneous:
MISCELLANEOUS: Present with 1340 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MNTSELSIAEEIDYEALPSHAPLHSQLLAGAFAGIMEHSLMFPIDALKTRVQAAGLNKAASTGMISQISKISTMEGSMALWKGVQSVILGAGPAHAVYFGTYEFCKARLISPEDMQTHQPMKTALSGTIATIAADALMNPFDTVKQRLQLDTNLRVWNVTKQIYQNEGFAAFYYSYPTTLAMNIPFAAFNFMIYESASKFFNPQNSYNPLIHCLCGGISGATCAALTTPLDCIKTVLQVRGSETVSIEIMKDANTFGRASRAILEVHGWKGFWRGLKPRIVANIPATAISWTAYECAKHFLMKN
The following text describes a protein:
Function:
Seems to be involved in the regulation of proliferation and migration.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Nucleus.
Sequence:
MLVRGRDQGSGSRLGPIVRRWAPRPSPLQSLAASLDAEPSSAAVPDGFPAGPTVSPRRLARPPGLEEALSALGLQGEREYAGDIFAEVMVCRVLPLRALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAALSLAHRLLDGAGSRLQPELYRCSLGGGSVWGHRSFRDLPSWSFLRSRRMRDNY
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MKRSFFINHLERFVNDEMSKKENFDDLKIVDIAEKKKHMICCDNINIDINDNNNDNNNDNICDDIMKKEIKKEKKRKKKKIEQIRNTLSSHCRIVEINDDEEISILDWNNIKSTKINEYIINSLINKFHFNNFLACQSNVLEYLLLYKYGSNCIKNGDIYIEVPTGLGKTLCYIISIIDYFLYNNENTLYCLILTATDELVNQIINVINIFELRNLKCMNIDMNNFHSNLYFDETINHKKFLSDCNILVTTTKKFEGLFYSNEDIFMNLRFLIIDEVDKIVAYTQCNICSIVNSLTNLVRKHQNNCANIYKPKYFLQKILVSATLCKVSDNLMSLDLYRPIFFYYMLNYKRNEEFYFFTKNKYTKMYTLIKLLLDDIPNKDMLSMLIFCGDEDSSHTLYRYLTIYFSYTNHSDYSIKEYSRELSNKRKKKILTNFLNQRVHILICNDNISRGLDTVNVNYVINFDMPKHYNVLTHRIGRLARYNSRRGTVYHFIKKKENIIMNKSGKQRNVNLIEQKRFKKNTLIDIKKNIMNLKKIVKSTIHMERKEKIKPHKFYSYDELMKLTNT
The following text describes a protein:
Function:
Has apoptosis-inducing activity.
Subcellular Localization:
Nucleus.
Sequence:
MLSCTTSTMPGMICKNSDLEFDSLKPCFYPEDDDIYFGGRNSTPPGEDIWKKFELLPTPRLSPGRALAEDSLEPANWATEMLLPEADLWSNPAEEEDIFGLKGLSGSSSNPVVLQDCMWSGFSSREKPETVVSEKLPGGCGSLAVGAGTLVPGAAAATSAGHARSGTAGVGRRKAAWLTELSHLDSECVDSAVIFPANKRESMPVATIPASAGAAISLGDHQGLSSSLEDFLSNSGYVEEGGEEIYVVMLGETQFSKTVTKLPTAAHSENAALTPECAQSGELILKRSDLIQEQHNYAAPPLPYAEDARPLKKPRSQDPLGPLKCVLRPKAPRLRSRSNSDLEDIERRRNHNRMERQRRDIMRSSFLNLRDLVPELVHNEKAAKVVILKKATEYIHTLQTDESKLLVEREKLYERKQQLLEKIKQSAVC