lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MYQVTLIFLALLPLTSTSRPYDVSSNEISSFNDPDFSDLRNTQTLCRTFPGMNRKQMQLCRRMPDVTAAAIQGIDMAVHECQHQMKNRRWNCSSLEMRHGNPFAHALMSRAGLKETAFAHSLASAGVLYQVTRSCSAGKLPYCGCDTRFVGSGEGFEWGGCSHDIKFGEGFAIDFLDSSEKSGRDAQARMNLHNKRAGRLAVSHYAEKRCKCHGMSGSCQLKTCWMQTPHFREVGNRLMEKFSLALEIRARNTNSGSVELVTRARSQFSTPRKKRRFPPQEELVFLEKSPDFCDADTRLDSPGTRERYCNRTSTGIDGCDSLCCGRGYNIRLERRTEWCNCTFHWCCYVRCQQCHSSQWVNQCK
The following text describes a protein:
Function:
May be involved in iron transport and iron homeostasis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MCSNGLAGIFKPQGHKSHSIHLPGDIDQHLWSCWCAFNSSSTILIEREWVVVLSEGHPPDLLTEMNSVIRRIDLTCKLVAPVITGFIISFVSLKASAMTLALWTTITVWVEYWLFMSVYNGIPALGESSLRRISEVSPSDEIPDSLSNDGENSAAAGKNSGSKFIECVAKVPYIDAWRVYLQQDVVLPGVALALLYFTVLSFGTLMTAAFEWEGIPAFVIGIARGISASIGIAATVVYPMVQSRILTLRTGLWSVWSQWNCLLLCVASIWVKNSHLSAYMLMGGVATSRLGLWMFDLCVIQQMQDLVPESDRCIVGGVQNSLQSTLDLMAYVMGILISNPQIHMRSMYYHKIIC
The following text describes a protein:
Function:
Histone H3 reader that is required for the ATAC complex-mediated maintenance of histone acetylation and gene activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Sequence:
MLDCVSAQMTSLSEPQEHRYTLRTSPRRAAQTRGSPTKNTSPYRENGQFEENNLSPNETNTTASDNVSESPTNPVEISQDEKVLCCDSENYGSEGLSKPSSEARMNIGHLPSAKESASQHTAEEEDDDPDVYYFESDHVALKHNKDYQRLLQTIAVLEAQRSQAVQDLESLGKHQREALKNPIGFVEKLQKKADIGLPYPQRVVQLPEIVWDQYTSSLGNFEREFKHRKRHTRRVKLVFDKVGLPARPKSPLDPKKDGDSLSYSMLPLSDGPEGSHHRPQMIRGRLCDDSKPETFNQLWTVEEQKKLEQLLLKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYIYSRKSSTSRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDERSCPHSHMSTAVEEASDEESIPVIYRSLPEYKELLQFKKLKKQKLQQMQAESGFVQHVGFKCDNCGVEPIQGVRWHCQDCPPEMSLDFCDSCSDCPHETDIHKEDHQLEPVYKSETFLDRDYCVSQGTSYSYLDPNYFPANR
The following text describes a protein:
Function:
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Subcellular Localization:
Chromosome, centromere. Nucleus.
Sequence:
MAARPRRHRSRYAKLPRGDFCEGAKKAMDAPSLTTSTEWDTQVVKGSSPLGPAGPGEEDLPSSPRLPSWLQPERCAVFQCAQCHAVLADSVHLAWDLSLSLGAVVFSRVTNNMVLEAPFQVGIEGLLKGSTYNLLFCSSCGIPVGFHLYSIHAALAALRGHFCLSSDKMLCYLLKTKAIGNASEMDIYNVPLPELKERIMLTHTRLNALMTILKEVTPGHSKPEN
The following text describes a protein:
Function:
Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine.
Subcellular Localization:
Nucleus.
Sequence:
EGITANPALCKMERKCPGHCGAPKKLELSFSIEEILKRPTESSRMVKTEGAGGQDTRQAAGVSSGLERPPQAQPQEERKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRNQLAARINLPEARVQIWFQNQRAKWRKQKTGSLGASQQLSEAGLALATNLDVAGPMLPPSIPPWLALPTGCYPPAPGQPASAWFPGQITLLPGHLWETQPLLGSLIQQTCIPALCCLPPANSKWGSPCATST
The following text describes a protein:
Function:
May be involved in the turnover of nuclear polyadenylated (pA+) RNA.
Sequence:
MNIENQDAFFQWLCDELTPIADADPIALAKYVLALVKKPDKGQEELKEFTKEQLNVFLQDHTAPFVDKLFDALTSKSYLPAESAKPAQAAPKQTSPPKEEASKPESARQSSPSSGVQKPSSSSSSSKSDNKPARKRISPPPSENREKEKSARDKERRRSRSPRDRRGRQAPSSRSGRASSNDRDRERHRRRSRSRSRSSSGSRTPPYKARSSRRRCKDFEERGYCIRGDQCPYYHGRDPVVVDENALSSMVPIPSAPPNFSLPPPGYNAINPPPPGVVVSAGEYNPETPALTNYSMPPPPIPGTIPGTIPGGWSQQLPAAPQYVPQPVTNFSQPPPSTGGAVPIVPQQPGSFRGGIRGRGAPRGRGSFTRGGFAGNINRENCTLQVAKIPAEMNNIAKLNEHFATFGVVDNIQVRYNGEIDAALVTYASKHDAYKAYKSPAPVLNNRFIKVFWHNPGGEGIDAAAAKSNAPTSPPKPTERPKIATVQESKFVNVAALNHRKQLQEAKEKLTNEKSLLSALVEAQNQHNVILDKWLARQKELLIKARTSPDEAERKNATKLVKHLHKKVKACKEEIDSILLKISEKSMLVDEIVAQIESLKSPNKFEDPSRKRKAASDGEEPQNKLNSIVVVKHVKEELVTDLMAHMEKFGEVFDHSVKAEDDGLMTAVFPFRKTADALTVMEEGKVLNGVSLDMELKTEKIEEIPSTDTNMSADQLLAAIPSSLESDEDDDLLND
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MEAPTPPSPTELDAAERIILLWDSTASEEARERMIFEGHRDEVDRYLQAVDEIQRSMSSASLVSVDDQAKLNSAIQIAMARLEDEFRNILLNHTSPIEPDSLTSTDPSSSTHSCSADSVSEFEDYSAEDDSGLTTPKASSASVGDADELLQRGDSSNTCSYRSTSSIRELDLIPSDAVVDLRNIAERMIAAGYLRECIQVYGGVRKSAVDSSFRRLGIEKLSIGDVQRLQWEQLEAKIRRWIRAAKACVRIVFASEKKLCEQIFNGIGTAIDDACFMETVKGPAIQLFNFAEAISISRRSPEKLFKILDLHDALMDLMPDIESVFESKSSESIRIQAVEILSRLAEAARGILSEFENAVLREPSKVPVPGGTIHPLTRYVMNYISLISDYKQTLNELIVSKPSTGSRYSGDPTTPDMEFAELEGKSPLALHLIWIIVILQFNLDGKSKHYKDAAIAHLFMMNNVHYIVQKIKGSPELREMIGDDYLRKLTGKFRQAATSYQRATWVSVLYCLRDEGLHVSGSFSSGVSKSALRERFKSFNAMFEEVHRTQATWLIPDSQLREELRISISEKLIPAYRSFLGRFRSHIESGRHPENYIKYSVEDLETAVLDFFEGYSVSQHLRRRSQ
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MFSSTASRGLRLTGKICSGSRAQIHISSRHNLLYGYWAYVLGERTTKRFGANSKIITVDGNLASGKGQLAKKLADRLGMRYFPEADEHYLDKTTGDGSILPSKFSGNCSLDKFYNDPKCPDGNSYRLQYWMYSVRLMQYSDALEHLLSTGQGAVLERSPFSDFVFLEAMYKNGYIRKQCIDHYNEIKGNSIDEFLPPHLVIYVDVPAAEVHKKILEKGHTSEKKAALPYLQSIEDTYKDSFLPQISEKSEVLKYSGNEVQDVEKVVEDIEYMKFDKGPWTEQTDVTFHHLRMFVEDKDKVASLITVPRYIPEITIGASEYDSAYYQYRSLPGRKYAKGYNADIGDKMIWLK
The following text describes a protein:
Function:
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly.
Subcellular Localization:
Mitochondrion.
Sequence:
MAAARALSLTAEAFGAAIPRRQGRLLTRWETTSSIPEAGEGQIRLTDSCVQGI
The following text describes a protein:
Function:
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Phosphorylates LATS1 and LATS2. Plays a key role in neural tube closure during embryonic development through LATS2 phosphorylation and regulation of the nuclear localization of YAP1 a critical downstream regulatory target in the Hippo signaling pathway.
Sequence:
MESLVFARRSGPTPSAAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWVNWGYATRVGEQEAPHEGGHPGSDSARASMADWLRRSSRPLLENGAKVCSFFKQHAPGGGSTTPGLERQHSLKKSRKENDMAQSLHSDTADDTAHRPGKSNLKLPKGILKKKVSASAEGAQEDPPELSPIPVSPGQAAPPLPKKGILKKPRQRESGYYSSPEPSESGELLDVGDVFVSGDPKEQKPPQASGLLLHRKGILKLNGKFSQTALELAAPTTFGSLDELAPPRPLARASRPSGAVSEDSILSSESFDQLDLPERLPEPPLRGCVSVDNLTGLEEPPSEGPGSCLRRWRQDPLGDSCFSLTDCQEVTATYRQALRVCSKLT
The following text describes a protein:
Function:
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MADLLDDVWGSGDDLDESTRELSPDLLKLKDNHSKRGYLDGIVSAKEENLQDGFDMSFPLGAELGLRVGKIIGRLQGLEYRYGKDDEELKKDFNNAKQELQIKNILTKRIFTEDYNLEDSKHPVVSKWEEIVTKYCEKYNVKTE
The following text describes a protein:
Function:
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein.
Sequence:
MTESKNSFNAKQTLEVGDKSYDYFALSAVKGMEKLPYSLKVLGENLLRTEDGANITADHINAIANWDPSAEPSIEIQFTPARVLMQDFTGVPCVVDLATMREAVKTLGGDPDKVNPLNPAEMVIDHSVIIEAFGSTLALAKNVEIEYERNEERYQFLRWGSKAFSNFRVVPPGTGIVHQVNIENLARVVFDNNGLAYPDTCIGTDSHTTMENGLGILGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIPAGVTATDVVLTITEMLREHGVVQKFVEFYGNGVKSIPLANRATIGNMSPEFGSTCAIFPIDEETVKYMHLTGRSEEQVALVEAYAKAQGMWLEQDAPEAEYSEYLELDLSTVVPSIAGPKRPQDRILLTEAKEQFRKDLPDYCSAEPVDESLPAKRMDSEGAVQKEGEDVAGYNSSRAGHGESAAEGAAGRQSNPVVVSSPNGGEYTLDHGMVAIASITSCTNTSNPSVMIGAGLIARKAAAKGLKAKPWVKTICAPGSQVVDGYYKRADLWKDLEALGFYLSGFGCTTCIGNSGPLPEEISAAINENDLTATAVLSGNRNFEGRISPDVKMNYLVSPIMVIAYAIAGTMDFDFETQPLGQDIDGNDVFLKDIWPSTEEIEETIAGAISRELYEADYADVFKGDEQWQNLPTPEGKTFDWDEKSTYIRKAPYFDGMTMEPAPVSDIKGARVLAKLGDSVTTDHISPASSIKPGTPAAQYLDENGVARNDYNSLGSRRGNHEVMMRGTFANIRLQNQLVDIAGGYTRDFTKNGEQAFIFDACQNYKAAGIPLVVIAGKEYGTGSSRDWAAKGTNLLGVKAVITESFERIHRSNLIGMGVIPLQFPAGESHASLGLDGTETFDIEGIEELNNGVTPKTVHVTATKESGDQVEFDAVVRIDTPGEADYYRNGGILQYVLRNMINA
The following text describes a protein:
Function:
May function as a N-methyl-N'nitro-N-nitrosoguanidine (MNNG) export permease.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTKSVGDEESQYIEDPSFAAAAAFTGGRDGVSYSNQRFAEGSGHSSDLAKSLEDYRPPDEKPSSLSSVGEGGANEEEKGGNDGGPLARIQTGLFSPRLRNHRKKILSKFVLNNFFIACVCVSLISIYWGACYGTDRYFFKVKNIVVLQDAPSNTSVQSISAIIPSLLASVPGTWHIYNATSFHRKFGTTNSTEIDRKIVDLIYDERYWLALNVKPNATDTLYNSLISQDANSEFNSSIFFESVFESGRDPSSVKSTILPLMQQLEVRLQKYYVKEYLPSLMSNITSNDRDLNINMENWAIAGQLLFTYNDYRPFADRILMAPLQVGLIYCILLTVLQLSLYGKLHGEMARVLKPKHILIYRLLISWATYFLLSIGFCTVSAIFRIDFTPAFGRGGFVVYWMSTWLVMMAVGGANENVLSLVIAYCPPYLSIWLMTWIILNISASFYPMVLNNEFYRYGYIMPIHNAVDIYKVIFLNLTKRKMGRNYGILVAWVALNTSLMPFCMKFAGKKMQKNAMQAAEAAVAAATQRASRPAEANTDKNNNPPGN
The following text describes a protein:
Function:
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins (By similarity). Regulates the localization of S protein at cis-Golgi, the place of virus budding. May act by binding cytoplasmic c-terminus of S.
Subcellular Localization:
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Host membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Sequence:
MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFLYIIKLIFLWLLWPVTLACFVLAAVYRINWITGGIAIAMACLVGLMWLSYFIASFRLFARTRSMWSFNPETNILLNVPLHGTILTRPLLESELVIGAVILRGHLRIAGHHLGRCDIKDLPKEITVATSRTLSYYKLGASQRVAGDSGFAAYSRYRIGNYKLNTDHSSSSDNIALLVQ
The following text describes a protein:
Function:
Regulates cell surface growth, bud formation and morphogenesis. May act indirectly by regulating factor(s) involved in these processes.
Miscellaneous:
MISCELLANEOUS: Present with 647 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Mitochondrion.
Sequence:
MIPPRIVPWRDFAELEELKLWFYPKSKGTIEDKRQRAVQRVQSYRLKGSQYLPHVVDSTAQITCAVLLDEKEACLGVHQDSIPIRLSYVMALIRFVNGLLDPTQQSQFAIPLHTLAAKIGLPSWFVDLRHWGTHERDLPGLEMLRWAANEALSWLYDHYWNDEELEDDRDDDDDDDDTGYGYRRNDKLEKYMESLTKTLDKWKRLRNEFLEYKWVWENANDSLITSSNFSGDNLVNYDAEKRKSSHASSSETMIRENLRQWQELWKLSIYHNVVLEKFFNNYDPLLLKVLMLNLNNFDWKVIEWVARNYRTQQDDSNITTILKRKFNAWKELQKRLLDVIINNLNNKNFKNKWQNWEKLIDENASYLILYFCQSMLAKLETEKITGNSWRNKKRRKQIDSTVEIEAKLKENIDNLSLRFNEGEIKLYDFIPAEKDSVPLKKEVSPALKADTNDILGDLASLKQRMSSFGTVGKKNKQEENRATPVKNWSRVQNWKPKPFGVL
The following text describes a protein:
Function:
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
Sequence:
MSLVRSFIAVDIESPDVIKKIEEVQREVLRLGLDIKLVERENLHITLRFLGEIPQSRVDSIIKALASVKFNKFMIKLAELGVFPDLSRPRVLWIGVSQGAEELTKLANIVRETVDKYAEHKEDREFTPHLTIGRIKSGQNAHKLREFVQRYKGVEFGVVAVEKVKLKRSVLTPRGPIYSDLFVLHLT
The following text describes a protein:
Function:
Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.
Subcellular Localization:
Cytoplasm.
Sequence:
MASRQPEVPALEPSGPLGKMSLPIGMYRRAFSYDDALEDPTPMTPPPSDMGSIPWKPVIPERKYQDLAKVEEGEASVSSPAVALSSATDGVDKVPVVKAKATRVIMNSLITKQTQESIQRFEQQAGLTDAGYTPHKGLTTEEIKYLRVAEALHKLKLQSGEITREEKQPASAQSTPGSTPHSSPKQKSRGWFASGSSTALPGPNLSTMDSGSGDKDRNMADKWSFFGPRSLQKSDSGGFATQTYRGAQKPSPMDLIRAQATRMAEDPATFKPPKMDIPVIEGKKQPPRTHNLKPRDLNVLTPTGF
The following text describes a protein:
Function:
Is involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MEQVKLFGAFPSPFIYRVIWALKLKGVQYDYIEDDDLFNKSNLLLEYNLVHNKKAIVLFVEFQLQMFWSVGEQQEKALKEASEVLKTIEECGGLGEKKFFGGDS
The following text describes a protein:
Function:
Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R-dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants.
Sequence:
MKTFQLANESSSLLSLSPKFILPEDERPQLSEVTSLDSIPIIDLSDHSYDGNNHSSSLVVQKISQACEEYGFFQIVNHGIPEQVCNKMMTAITDIFNLPPEQTGQLYTTDHTKNTKLYNYYLNVEGGEKVKMWSECFSHYWYPIEDIIHLLPQEIGTQYGEAFSEYAREIGSLVRRLLGLLSIGLGIEEDFLLKIFGDQPRLRAQANFYPPCPDPELTLGLPVHTDFNALTIVLQSQVSGLQVIKDGKWIAVPVIPNAFVINLGDQIQVLSNGRFKSVHHRAVTNKLSPRVSMAMFYGPNVDTTIGPIQDLIDEEHPPRYRNYRFSEFLEEFFKQEGTRRMVKEVFELPC
The following text describes a protein:
Function:
Expression is induced during oxidative stress. Plays an essential, SCF-independent, role in the stress response to hydrogen peroxide for survival, by negatively regulating ergosterol synthesis via direct binding to the squalene synthase erg9.
Subcellular Localization:
Cytoplasm. Nucleus. Endoplasmic reticulum. Note=Associated with vesicle-like and endoplasmic reticulum (excluding a nuclear rim) structures.
Sequence:
MLQFSFQNCKTHTCYMNTSVNEHLDQDESFLRILIDTRKKIRSSYFKPQTFDEFVHCLARVRAMKRLVSICSNFDEEDNWNGVWNTLVVDGDSHASAMIDYEGLLDKCSLSRNLLELINDYAEYTTQVLPFRKIPSSDNLDSSLNLTVASPKSNLYYRYSSESPKYAKILDCPDEILQLIFSYCYDASYIEKLPFAFSYRKQRHTLIHDLPNTCLRFKKILSPRNVSFWKRLLKVHKKNPNSAVTCSESINTSAVAKFTDIPTIIPIFLDPSYQSYAAKTIHSDTSSLASSIIQTGDGTQSCDESTYIELACNLVGRCVLCNRIPKLTKFKDCITSFYRPSVATNICDQCLEAIIDFYEPVSRYKFDVMKDRLGVGYISRPGQKFPSWLSEHVQLARDEEKAFKSIYHSQGEFARSLFRLFRAQLAELCEQ
The following text describes a protein:
Function:
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
Subcellular Localization:
Cytoplasm.
Sequence:
MTVETFHPKQTTTLETPAKTLEAASADSVNTGNVATGNRIGFVSLGCPKNLVDSERILTQLRIDGYEVTNSYDNADLVIVNTCGFIDAAVEESLDAVREALEENGKVIVTGCLGAKENQIREVHPDVLEITGPHSYEAVLKHVHKYVPKPEHNPFTSLIPQTGVKLTPKHYAYLKISEGCDNRCTFCIIPALRGDLDSRGAGSVLDEAKRLVEAGVQEILVVSQDTSAYGKDKGGRTDFWNGMPVKQDITSLARQLGKMGAWVRLHYIYPYPWVDDLIPLMAEGLILPYLDIPMQHASPRILKMMKRPGRVDRQLEAIQRWREICPDLVIRSTFIVGFPGETEEDFEMLLDFLREARLDRVGCFKYSEVEGAVANTIAELISEEVKEDRYHRFMEVQAEISAERLARFVGRTMDILIDDVDEEGAIGRSFADAPEIDGMVFINGETELEPGMLVRAVITHSDEHDLWAELVDADAEDEVEA
The following text describes a protein:
Function:
Catalyzes the final step in the CDP-choline route leading to phosphatidylcholin (PC). Preferentially uses CDP-monomethylethanolamine as aminoalcohol substrate. Shows highest activity toward di- and mono-unsaturated diacylglycerol species as lipid substrates. The CDP-choline pathway only contributes to net PC synthesis if exogenous choline is present. In its absence, this pathway recycles choline from PC turnover and may contribute to maintaining the proper PC species composition.
Miscellaneous:
MISCELLANEOUS: Present with 981 molecules/cell in log phase SD medium.
Subcellular Localization:
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein.
Sequence:
MGFFIPQSSLGNLKLYKYQSDDRSFLSNHVLRPFWRKFATIFPLWMAPNLVTLLGFCFIIFNVLTTLYYDPYFDQESPRWTYFSYAIGLFLYQTFDACDGMHARRTGQQGPLGELFDHCIDSINTTLSMIPVCSMTGMGYTYMTIFSQFAILCSFYLSTWEEYHTHKLYLAEFCGPVEGIIVLCISFIAVGIYGPQTIWHTKVAQFSWQDFVFDVETVHLMYAFCTGALIFNIVTAHTNVVRYYESQSTKSATPSKTAENISKAVNGLLPFFAYFSSIFTLVLIQPSFISLALILSIGFSVAFVVGRMIIAHLTMQPFPMVNFPFLIPTIQLVLYAFMVYVLDYQKGSIVSALVWMGLGLTLAIHGMFINDIIYDITTFLDIYALSIKHPKEI
The following text describes a protein:
Function:
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Sequence:
MRLRKVKNALLKINQSPYFYSKDKFAKFTKKQLVLELGCGKGTFLIKEAQKNNNFLFIGIEREPTIVLKAINKINKLDFNLENILLLCTDAKQLDDYFQAESVQKIFINFPDPWPKKRHIQRRLTSPDFLKLFWNLLVKNGLIEFKTDNDKLFEYTLTTLQENSQIFEIIHQITDLNNSEFSFQNSITEYEQRFMELEIPIKKLVIKKII
The following text describes a protein:
Function:
Involved in degradation of plant cell walls. Hydrolyzes of the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.
Subcellular Localization:
Secreted.
Sequence:
MKTSIVLSIVALFLTSKASADCWSERLGWPCCSDSNAEVIYVDDDGDWGVENNDWCGIQKEEENNNSWDMGDWNQGGNQGGGMPWGDFGGNQGGGMQWGDFGGNQGGGMPWGDFGGNQGGGMPWGDFGGNQGGNQGGGMPWGDFGGNQGGNQGGGMPWGDFGGNQGGGMQWGDFGGNQGGNQGGGMPWGDFGGNQGGGMQWGDFGGNQGGNQGGGMPWGDFGGNQGGGMQWGDFGGNQGGGMQWGDFGGNQGGNQDWGNQGGNSGPTVEYSTDVDCSGKTLKSNTNLNINGRKVIVKFPSGFTGDKAAPLLINYHPIMGSASQWESGSQTAKAALNDGAIVAFMDGAQGPMGQAWNVGPCCTDADDVQFTRNFIKEITSKACVDPKRIYAAGFSMGGGMSNYAGCQLADVIAAAAPSAFDLAKEIVDGGKCKPARPFPILNFRGTQDNVVMYNGGLSQVVQGKPITFMGAKNNFKEWAKMNGCTGEPKQNTPGNNCEMYENCKGGVKVGLCTINGGGHAEGDGKMGWDFVKQFSLP
The following text describes a protein:
Function:
Metalloprotease.
Sequence:
MRLIHSSLLFFACFGSALSVGVLPIPNEHASNIKAKFDDYAEHYLLPEDFHNAETAPVKKPTDAEIESMQNSLLFEGDIMGVPEIEKTDILKRLRDDPLIDDDEIFTKPFHSALNLVTYPDKLWPEGQVPYMLEEGMTNDQRTAIAQAFDEYKTKTCVRFVPKTDDDFDYIYVKRNVAFGCSSYVGRAGGNQTVSLEVDKCFSKGIIAHELMHALGFFHEHSRTDRDDFVDINEDNIRPGMMRNFEKYPRKIIDSLGMPYDYESVMHYHKLAFSRNGKPTIVPKDNEADVGQRYKLSEMDSKKVNKLYQCGEYSKTSYTTTTTTTTTTTTTTTTEEPTTTTVEEVEEKSKEKETSSTTTTTKKPTTTVATTTSTTPKPVERSRNKKCEDLNAHCGMWEQLGHCQHSVKYMAHYCRKACGLCEIEVTTTTAKPLPRNKEKENKSSTSSSIFSSTPRTTITTTTQPKEKCEDKNLFCSYWAKIGECNSESKFMKIFCKASCGKC
The following text describes a protein:
Function:
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal, which allows E.coli to grow on putrescine as the sole nitrogen source. Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Is also able to transaminate spermidine, in lower extent, but not ornithine. Alpha-ketobutyrate and pyruvate can also act as amino acceptors, although much less efficiently.
Sequence:
MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
The following text describes a protein:
Function:
Possesses E3 ubiquitin-protein ligase in vitro.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MAHRRIALAVLVTLLLSAFRPCLAQQSNDDTSKHHRSATAGGFTPTTVVVLVALITAFVLLTVFSVLINRCAQARAPPRRAFRSTASHQPVGGAAAASRASRGLDKEVVEAFPTAVYGDVKARMAAKSGPLECAVCLAEFADSDELRVLPACCHVFHPDCIDPWLAAAVTCPLCRANLTAPPVSLAAAESSDLTAPEEAVQEEESEELDEASLMATFTPESVIDFGATHDHEFDRAGYPHYRRTQSAMDAAPDRHTLRLPEHVMKELAADRRHRRAASLAGYPDSVERTPRWLTSLWRSVSWQRQSRADWDAGEEHGGSKRVHPVAGAQDETPSGSGSDGSKENSDSDALNRV
The following text describes a protein:
Function:
Sequence-specific transcription factor (By similarity). Regulates multiple developmental processes including brainstem, inner and outer ear, abducens nerve and cardiovascular development and morphogenesis as well as cognition and behavior (By similarity). Also part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments (By similarity). Activates transcription in the presence of PBX1A and PKNOX1 (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MDNARLNSFLEYPILGSGDSGTCSARVYSSDHGITTFQSCAVSANSCGGDDRFLGGRGVQITSPHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGAQNFSAPYGPYGLNQEADVSGGYPPCAPAVYSGNLSSPMVQHHHHHQGYAGGTVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYVGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARSEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPMSPATPPGSDEKTEESSEKSSSSPSAPSPASSTSDTLTTSH
The following text describes a protein:
Function:
Mediates H(+)-dependent pyridoxine transport.
Subcellular Localization:
Lysosome membrane; Multi-pass membrane protein.
Sequence:
MGIQYDEDSKMNPHLDRFATYRRRWYILAIFSVLCFTQGMVWNTWGPVATSAEYYYGWTDSDVAMMANWGTIMYVVTVFFWSYLFDTVGSRIPIVSAAFCIALGTGLRIISRESAVATPLIHIAQILNGFAGPIALGGPPIISALWFPPRQRTTSTAITTIFSYLGVATAFVLGPNMVYEVKNATDTNSSVPKSNLVFYLNSTNSDEIRQKVGDQMWDFLLIEFIISVVIFLCMLIYFPSRPKLPPSVSASKDRMNLKDGVKSLIRNKSFWNLFICYGASTGVYAAWGAVLNVNLQSFNVDQILAGWLGFYANIAGCVAGVTLGFFSDIFAGKMKISLICMMIGSTVSFLWFTLVCFKYVPFSEASLYITSILGGLFVNGAIPLYYELNMEVCYPVPEGITSGALTMSNNAFGIFFLLLFLIPNIGSLWTNWLLLGCCAACVPLLLFFNGRYNRLELDIPQDVTTVNGVHKDDTNNKA
The following text describes a protein:
Function:
Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase during oocyte maturation. Required for embryonic development, germline proliferation and initiation of meiosis during spermatogenesis. Required for chromosome structure during mitosis and negative regulation of nuclear envelope breakdown (By similarity).
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein. Cytoplasm.
Sequence:
MDETENNTSIDSVEVGPSSPRVVATPRIPIPVMMRETPLSTKRERQALTPRFRRPAPRMIKTVPQTRSIWSVRKDTTPQLVTPHGPQELESPHYDRANTQTFFEQVFQIDEIIGRGSFGEVFAARCREDSRLYAVKVSIAPMRQHSMSKYREAESHMIIPPHKNLVKFYRAWEETDRLYIQTELCEQSLQQYCSVQHALPENEIWNIFVDLLEAVHHLHSNDMIHDDIKPENIFLTKHKICKLGDFGLVINLKNPNDVKSAEEGDSKYLAPEVLNGKPTFASDIFSLGVTILEAATDLDVPSNGDAWHQIRNGQIPERFFVGISSDLRVLIEQMINKEPMKRPTSDALRKHLSIRTRLDSRRRYILSMDMRDGFCNLMSSILVWCMAFLSVVFHPVTRFHEAINNRRSELCAQFVNNQQHTPIQTPETSKVYSESLTGVALRQASQISPFDFSDDENPPHSQRRLFTGPVSRRLNFDDEMEDEEQATCSSSNSSAIETAEDSLSSPKKPVIPVTRQGTPKSARRLIPSYRNRSGSRDPTHHAGAGDSMNSSILDQERTDRYLRMRLAEQQLDWNDHSNMIDEAPPPMSCPPRIRRSLRDMPRMPVLNFNLLDEPIKKGKEKPVVEPAELRQRPMRNGLKSLRSRMASFQGSSGDEN