lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
(Microbial infection) Acts as a receptor for Epstein-Barr virus.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MGASSPRSPEPVGPPAPRLPFCCGGSLLAVVVLLALPVAWGQCNAPEQLPFARPTELIDESEFSIGTHLKYECRPGYYGRPFSIICLKNSVWTSAEDKCIRKSCRNPRDPVNGMVHVIKDIQFGSQINYSCTEGYRLIGSSSATCIISDNTLIWDNETPICEKISCGLPPTIDNGDFFSANKEYFHYGSVVTYHCNLGSGGRKLFELVGEPSIYCTSNEDQVGIWSGPAPQCILPNKCTPPNVENGILVSVKRSLFSLNEVVEFRCQPGFVMKGPRHVQCQALNKWEPELPSCSRVCQPPPDVLHGERIQRDKDIFQPGQEVFYICEPGYDLRGAASLRCTLQGDWSPAAPRCEAKSCDDSLGQLPNGRVLFPRSLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVTYICDRHPDRGMTFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCKAPDHFPFAKLKTQTIASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECVISGNTAHWSKKPPICQRIPCGLPPAIANGDFISTNREYFHYGSVVTYRCNLGSGRKKLFELVGEPSIYCTSKDGQVGIWSGPAPQCIIPNKCTPPNVENGILVSVNRSLFSLNEVVEFRCQPGFVMKGPRRVQCQALNKWEPELPSCSRVCQSPPDVLHGERTQRDKDIFQPGQEVFYICEPGYDLRGAASLRCTPQGDWSPAAPRCEVKSCDDSLGQLPNGRVLFPRSLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVTYTCDPHPDRGMTFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCNAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECVISGNTAHWSTKPPICQRIPCGLPPAIANGDFISTNREYFHYGSVVTYRCNLGSGRKKLFELVGEPSIYCTSKDGQVGIWSGPAPQCIIPNKCTPPNVENGILVSVNRSLFSLNEVVEFRCQPGFVMKGPRRVQCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDKFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLHHGRVLVPFNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGALLGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPQGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECHPGYFGRMFSISCLENLVWSSVEDNCRRKSCGTPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKEAPICEIISCKPPPTISNGDFYSNNRTSFHSGTVVTYQCHTGPDGEQLFELMGERSIYCTSKDDQVGVWSSPPPQCISTNKCTAPEVENGIRVPGNRSFFSLNEIVRFRCQPGFVMVGSHTVQCQTNDRWGPKLPHCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPICTVKSCDEFLGQLPHGRVLFPFNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGAPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRCTSDLQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVTLYLPGMTISYICDPGYLLVGKGIIFCTDQGIWSQLDHYCKEVNCSFPQFMNGISKELEMKKVYHYGDYVTLECEDGYALEGSPWSQCQADDRWDPPLAICTSRTRDALIVGTLSGMIFVILFIIFLSWIILKYRKGNNAHEKPKEVAIHIHSPGGSSVHPQTLQTNEENSRYLYTY
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation and early development. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR.
Subcellular Localization:
Cytoplasm.
Sequence:
MDFRRGKKNCCYPAYGEWLAHRAFGPFIGAKQHTNWKHTHDGSGSSTVSSMLLAPEQQDHPAAVPSDEELSLGLLSLALPCWYQELWSRPEAQRDVQTPLNLLGSSRGDGDWVQHQALQAHESAGGRDSLTPTLETHSLLHSGSSSPVNSENSAVSSGSEHLASLRVSPPLPLLLSGLRVEDLKLGSDVGLDQNPLNTFMNASSGRAEGSVFSRWSTGPVWPGWDTLGLNKPSFCIEREAKLHKQAAAVNEASYSWEGSLPPRHYKTPVYSCKVFLGGVPWDITEASLQSTFSVFGPLKVEWPGKDGKHPRCPPQGYVYLLFDWEKSVKSLLQACTQHRLQADDYLQFYYKLSSRRIHSKDVQVIPWVISDSNFIRCPSQRLCRNKTVFVGALHGMLNAEGLAHIMDELFGGVMYAGIDTDKHKYPIGSGRVTFRSQRSYLKAVTAAFVQIKTSKFTKKVQIDPYLDDSICQICSSQPGPFFCRAQACFKYYCRSCWHWRHSLDVLSSHQPLMRNQKSLNPT
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MDLRASAESGHNNELTMTEERKITSTPVMEFYRDKCVLITGGTGFIGRLLIEKLLRINVRQIILLSRPKKGKTTQQRCDDLFSSIVFMNLKKDCPTFIERVKLVDADLQHPSLGLSDESIEYIVNNAQIVLHAASDVRFDQALKKAIEVNVRGTRDLLRIAEKIVNLELFVYISTAYSNCPQGLIKEQFYTPPSEPEKMIQLVEAMDERFEEHMNKTVNDFIHPWPNTYVYTKALTEDVVRQYGELLPIAVVRPSIVIATNEEPIGGWTDNIYGLNGVIAGVALGIIRIMHVDDNNKADIIPADIVVNTVLAAGWQTYVERFIYHHLRKGDRPLPEAKTNGELKGVAKPRTKIYNCVTGNDNPISYQKIYKYSIEVGKHCPPKKSLWIVCHNTTTNKYLYEFYKVIYHLLPALLIDTYLRVIRRTPRVMDLYRKVHKFATVIEYFANGRWTFENDNLKSLREKLSPDDQIMFQCNIQKIEWADYFWTYIHGLRKHIANEPLENLDEAIKRHKQMRIVHYFILAAYYSIWALLIFYLCKAVGMLVF
The following text describes a protein:
Function:
Acts as a transcriptional transactivator of ELL, ELL2 and TCEA1 elongation activities (By similarity). Potent inducer of apoptosis in prostatic and non-prostatic cell lines.
Subcellular Localization:
Nucleus speckle.
Sequence:
MNGPAGLAYLDRRERILKLGESFEKQPRCAFHTVRYDFKPASVDASCEGNLEVGKGEQVTITLPNIEGSTPPVTVFKGSKRPYLKECILIINHDTGECRLEKLSSNITVKKTRGEGSSKIQCRLEQQQQQMWNPPRTSNLVQHSPSEDKLSPTSLMDDIERELKAEASLMDQMSSCDSSSDSRSSSSSSSEDSSSDSEDDDRSSPSGPRRYSSEHPSVSAGPQYRTSDADTTCNRLYDNSALLMSTLRSDLQLSESDSDSED
The following text describes a protein:
Function:
Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. In low periplasmic Mg(2+), PhoQ functions as a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), acts as a protein phosphatase that dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG (By similarity). PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, or treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway; the 2 periplasmic Cys residues of MgrB are required for its action on PhoQ, which then acts on PhoP. Mediates magnesium influx to the cytosol by activation of mgtA. Promotes expression of the two-component regulatory system rstA/rstB and transcription of the hemL, mgrB, nagA, slyB, vboR and yrbL genes.
Miscellaneous:
MISCELLANEOUS: There is a close linkage between the PhoP/PhoQ and Rcs signaling systems, and both signaling systems respond to certain external divalent cations (zinc and magnesium); MISCELLANEOUS: Two-component regulatory system EvgA/EvgS interacts with PhoP/PhoQ via signal transduction mediated by phospho-EvgA.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSFDKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDVPWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVAVNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSLRPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLTHSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMRGGTLLSRELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACKYCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAREITEQYEGKIVAGESMLGGARMEVIFGRQHSAPKDE
The following text describes a protein:
Function:
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MARRPRPDGPQHLLALVRSAVPPVHPAGRPFIAAGLAIAAVGHRYRWLRGTGLLAAAACAGFFRHPQRVPPTRPAAIVAPADGVICAIDSAAPPAELSMGDTPLPRVSIFLSILDAHVQRAPVSGEVIAVQHRPGRFGSADLPEASDDNERTSVRIRMPNGAEVVAVQIAGLVARRIVCDAHVGDKLAIGDTYGLIRFGSRLDTYLPAGAEPIVNVGQRAVAGETVLAECR
The following text describes a protein:
Function:
Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase.
Subcellular Localization:
Nucleus.
Sequence:
MDIDEDEDFYAPDEPQAAPPTTAATTTTPATTTTTAAPTTTTTTTSTTTASAPPTTTSSSTKPEDELEEGEEEDEGGGAMDEDDDSDIDIITERKDGSAPPPPVQSRYSEIRNIPQRAAANDNGVKTAPVKKSDGTNSNSNSSSNKFGGGGGIGNEQKTRQGSGAAGGSGAELPPVRTSKIEVDGIPVYKPVGKPITGVVIDEDLPENDKPWRKPGTDLSDYFNYGFDEFTWALYAQKQEALRGEYNAEAIAANNKKMMEEMTNMMMMGGMMPPGMGGPGGPGVGPAGPGAMGPGGPAGAGGMGGPGGGLDGMPPEMQAMMQQMMGAAAAQGMDPSQMGQMGMAGGPGDMGGMGGMFGGPGGGPGGPGTGGMGPGGPGGQGGQGQQFGGGFGGNQGQGGYGGYDQMGGAGGGGRGGRGRGRRW
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MSEYEDPYGYYEDTEITAEDCWTVISSFFNEKGLVSQQLDSFDEFIETTIQELVWEDRTLILDQPAQHTTPNDNQNKRFEITFGKIYLSRPTMTEADGSTHPMYPQEARARNLTYSSPLYVDMKKRVLFSIDDPARPEADVVWNPIPGEVEEPVSKVYIGKVPIMLRSKFCILRGLRENDLYELNECPYDQGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSAVEKGSRLISSMQIKMFGRSDKGPVTIKAALPYVRADIPIVVVFRALGVVPDGDILEHICYDNNDWQMLEMLKPCIEEAFVIQDREVALDYIGRRGSAVGVNRERRVRYARDILQKELLPHITQEEGFETRKAYFLGYMVHRMLLVALGRKEPDDRDHFGKKRLDLAGPLMAGIFRMLFKKLTKDIYRYMLKCVETNKDFNLTLAVKSNTITNGLKYSLATGNWGDQKKAMSSRAGVSQVLNRYTFASTLSHLRRTNTPIGRDGKIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTPSFPIINFLDEWGMEPLEDYVPHTHTTSTRVFVNGVWVGVHRDATQLTDMIKSLRRMGDIESEVSIIRDIREKEIRIFTDAGRVYRPLFVVENNPDAERKGELVLQKDHIYQLQQQMAEQAETEGDEGKGDKNTGWNWLVDNGVIEYIDGEEEETVMIAMTPEDLEFSRQMQAGVEMPEDELDPARRVKPAYNPHSHTWTHCEIHPSMILGILASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYDVRMDTMANILYYPQKPLATTRSMEFLKFRELPAGQNAIVAILCYSGYNQEDSVVMNQSSIDRGLFRSLFFRSYMDQERRVGMSVVEEFEKPTRADTLRMKHGTYDKLDDDGLVCPGVRVSGEDIIIGKTAPIPPDAEELGQRTKYHTKRDASTPLRSTENGIVDQVLLTTNQEGLRFVKVRMRTTKIPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGVVPDIIINPHAIPSRMTVAHLIECLLSKVSCLSGLEGDATPFTDVTVDAISKLLRSHGYQSRGFEVMYHGHTGKKIMAQCFLGPTYYQRLRHMVDDKIHARARGPVQILTRQPVEGRSREGGLRFGEMERDCMIAHGAAAFLKERLMEASDAFRIHVCGVCGSMNVIANLKKNQFECRSCRNKTKIYQVQIPYAAKLLFQELMAMNIAPRLFSDRSGYSVRV
The following text describes a protein:
Function:
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization.
Subcellular Localization:
Cell projection, lamellipodium. Cytoplasm, cytoskeleton, stress fiber.
Sequence:
MAANEQSICQARASVMIYDDTSKKWVPIKPGQQGFSRINIYHNTANNTFRVVGVKLQDQQVVINYSLVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQDGGPAAQRQAQNIQNGPSSDDMEIQRRQILEQQQRQETLERRTSTTVSTLQINVSSSPSHCQSPPPDYSNFSASPSTGAVPPPSYAKVISSAAASPELSSKSTHKSSNRTSEPPEMQNSHCGPEPSTSQSSAFSPIRPSNGTLSRSIKQISLSPPPAPGSHSPLTLHQSVRHPSLSFSPCSSSPPVSVNSSVRKSISPQSPIPVVLPVIPVQNSRVRGCSDKMVQIPIVSQTGPRDQAEEPLTSQISLSSPRTQVKCADRSFLSYIETVPVAQLPMITSPAGILSQAPPQPFQSSAHPSQPPYQSMSHFVSLPPPYAAVSELTLPKRTAPYMTSSTITQFSPMLPPVHSSSTAMVASVGSAPAPASGPPPPPPPGPPPPSGATPPPAPPLPAGGSQGVVYEESPASGLAAALAGAKLRKVQRPEDGSSSPCGATKTDANRTSSGGGGGGLMEEMNKLLAKRRKAASQTDKPGDKKEDECQNEDASLSSSPVTRGPTPQNSTDLGKKPWERSNSVEKPVPSLLSRTPPVVKSPEAKSPIQSQPPSRMKLVSSSNDVSSDAFDFDRMKQEILEEVVRELHKVKEEIIDAIRQELSRISTT
The following text describes a protein:
Function:
May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
Sequence:
MQNIIILDDMSYMRYRVKDLLEEKDIKVYETSTSFEFFNKLYEKKDNIDLIILELGLTREDGFEVVEKIREKNVDIPIVILTKVNTRDAFAKVIREGISDYILKPFDNKVLLDRIVKTIKESKASKEEVSIGKKSKVQKIYISEDNENIDKDKEEFAKGKEIADFNGIEEELPEEFKIYFVDELNKAKTDNTKVSSVVFTLIKNTDEEEKIDVKESYITLTEVFYKGIKDIFKAPNFITKHGLLTFVALLPNCDEEKVEDMKNRIQEKYKMLSLIYPQLSQYHVGYGNVTYPLDGDTVEALIDKLMDKMRENIKLKE
The following text describes a protein:
Function:
Mu-conotoxins block voltage-gated sodium channels. This peptide inhibits the cardiac sodium channel hNav1.5/SCN5A (33% inhibition at 200 nM, 50% at 400 nM, and 55% at 600 nM). Does not interfere with the voltage-dependence of activation, but affects the voltage-dependence of inactivation of hNav1.5. In vivo, intracranial injection into 9-day-old mice causes transient symptoms, including extension of the body and clockwise and counter-clockwise turns, that last 3 to 4 minutes. Intracranial injection into 16-day-old mice, causes transient symptoms, including agitated breathing and occasional turning followed by scratching and grooming behavior, that last for 15-19 minutes.
Miscellaneous:
MISCELLANEOUS: Negative results: shows very weak inhibition of neuronal sodium channels rNav1.6/SCN8A (14% inhibition at 200 nM), and rNav1.7/SCN9A (7%).
Subcellular Localization:
Secreted.
Domain:
The cysteine framework is V (CC-CC).
Sequence:
MRCLPVFVILLLLIASAPSVDAQLKTKDDVPLASFHDNAKGTQHKRIINWCCLIFYQCC
The following text describes a protein:
Function:
Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
Subcellular Localization:
Nucleus.
Domain:
The YDG domain mediates the interaction with histone H3; The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).
Sequence:
MWIQVRTIDGKETRTIEDLSRLTKIECLRLKIQEIFNVNPEQQRLFYRGKQMEDGQTLFDYNVGLNDIVQLLIRSQTDPPDAQGKKKEKDVTGCSSGTLTSNNNGNKSLSPQLDNQPSTSARTFLIDPGIGVYKINELVDCRDVSIGAWFEASIENVTRATKGQNGKATGKSGKMSKRTNGKLDQNHSSHGSNGNSNGNSAFNLDTAPSTSYMDCLNSEEDVTYHIKYDDYPENGVVEMCANDVRPRARTLLKWDHLRVGMVVMVNYNIEIPEERGFWFDAEITSLKEISRSNKEVKVKILLGGPDDVISDCKLLIVEEIYKIEKPGAPPLTSADGQFKRKSGPECKHCKADPEAECRFCSCCVCGGKQDAHMQLLCDECNMAFHIYCLNPPLSKIPEDEDWYCPTCKNDTSEVVKAGEKLKASKKKAKMPSAHTESQRDWGKGMACVGRTKECTIVPSNHYGPIPGIPVGTTWKFRVQVSEAGVHRPHVGGIHGRSNDGSYSLVLAGGFEDEVDRGDEFTYTGSGGRDLSGNKRIGEHSFDQTLTHMNRALALNCDAPLNDKDGAESRNWRAGKPVRVVRSSKGRRISKYAPEEGNRYDGIYKVVKYWPEIGKCGFLVWRYLLRRDDSEPAPWTPEGAERIKKLGLSVQYPEGYLEAMANKSKKDRGKRNSGKQDKPEKAEKKEKGKEEKKEPETCPQSNGSQKRPQETETQDHETPAKVGKLAEKGEAFQLSAQQQWLIREDCLNRKLWDEALNCIMEGPNFLRKVEQIFMCVCCQELVYQPITTECLHNVCKTCLQRSFRAEVYTCPACRHDLGKDYIMVLNKILQSLLDQFFPGYSKGR
The following text describes a protein:
Function:
RNA-binding protein involved in regulation of mRNA stability. Promotes mRNA stabilization by recruiting MKT1 and PBP1 (By similarity). Stabilizes transcripts encoding mitochondrial proteins.
Sequence:
MSHPQSHRYFSVNAPAGGERHLALDEKGVLCLTVVDPATRKLLIPLSCVYPTQAQQRTTIPSLCQLFLNGRCRQGTQCHQVHAALDVVAALRSQVDYLPICCALHGDRDYVNALDNRSWMSRVVVHVPDATYGGGYIPLARFSYTTPISRILREVNARLESGVSVAAVDGGGHPKRMVLNACDFKICGLHTLDRCRYAEECIFLHICKEIVVDVNNGSGDYSLTSQARDGGEPGPRGAKKGSVFVSVSRQQRVRGRPLSYPTVEYQTPFPLRSYEGSMSYNAVSDINSDCSWVSGRYPTGAYMESRMDAAPLPSLAPRFVQGHPGVPRCYSSTTTSTTTTAAAREDAAMYGAGGCWDRWSSPESGCAPCAFVGSCSDCHYADNNNYSGCNGYAYGSRNGYGSDGPNCYFCPGDECSSTHLCPNGTSSSVPQPVESVSSASVSARAWQHNPYGVTPTGGISD
The following text describes a protein:
Function:
Localized to sites of polarized growth and is required for efficient mating and bipolar budding.
Miscellaneous:
MISCELLANEOUS: Present with 7820 molecules/cell in log phase SD medium.
Sequence:
MHKFDLELSRRANPLLFSAERYEEYPLKYDELKQYLLSQNPSHPHHNSRPYTSIDYFDYLLYRSKNDESEIDLDKKLVSEFALYYVQKEHLNSDDLNPTLNELLKLQPKSADWYEMMLRILESINTTGIDQLTKENNNSFPNSKRARSSTNMGGTDKFNKGAYHTDKADDDKNEILQELTSFLMSNSIQKGIDIKPIPLDDPVKFLKNGINSILDTCVSLEKNTSSPPISPNAAAIQEEDSSKKLEELETAFSDLQLAHNFLTKQFENDRAEYVQDIEKLTRTNRELQDKLLNNHSNLSKTEKKLHELEQENKELEKANNKLNSSRHNFGMSSPASSPVTWDPSSPSSVGSPTSGSGSRSLSIMTSEFKKVLTSTQRKYEKELSDEREHRFKLERELALLKNAEANTSLALNRDDPPDML
The following text describes a protein:
Function:
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
Sequence:
MGKVILLPEEIRNKIAAGEVIERPVSVVKELVENSIDAGAKRITVEFINGGETLISVIDDGEGMTKEDAILALNRFATSKIKTEEDLYNIKTLGFRGEALASIASVSKVEVRSKTETEDGVFIKVEGGVIQEINLWQGSKGTVIKVFDLFYNVPARRKFLKSKTTETNLIVDFVKRIAMAYPEISFQLIQDGKNKFITSGNGKLEDVVSLLFDIEIHNNLIFLQRKEGNYIIEGFISKPGKLISLKSQDYFYVNRRWVRNNIILQAIKEGYKNRLLEGYFPFSIVFLTLPYHEVDVNVHPTKREIKFEKEKEVYEFVSKAIKEALDSEDKRFFSGVKALEGKEHKNHVGIKTEKELLSLPMEFEHKSENKLSEDISEYISLKSGFRIVGQIFDNYIIVETKDRVYIIDQHAAHERIRYEELKKELSLGYLQNVEILFPLVIEVSEEEKELLNKHKDLLEKFAFSWEDFGPYHIRIIRVPYEFLKFDSKSIENLFQEIISDISEKDLSKLEDKIIKSMACHSAIRSGNILVREEMEVLINLIFERKIPLTCPHGRPYIWEISKEELERYFHRR
The following text describes a protein:
Function:
Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I (By similarity).
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MAQSDPPKSPDPPLPTSIRNPQTPESGWDRIRELFQPNEQGHYPEEVGSIVKSAVTGALLGGIYGGLPAARHSKERYIQQSQAQIYQHRVEAVRSAHNAALRGFIRYGWRWGWRVAAFVTIFNSVSTGLTVYRDKLALSHYAAAGAVTGGLFRLNLGLVGLLSGSLIGAALGVPAGALISGLQSISGESIREKKRRERQELYENKVQEWSARLQVTDEVLEEMETSQQDPLEQQVEKIQELLQLPRNPAVSPKEGR
The following text describes a protein:
Function:
Deoxyribonucleoside kinase that has a broad specificity phosphorylating thymidine, 2'-deoxyriboadenosine, 2'-deoxyribocytidine and 2'-deoxyriboguanosine. Specificity is higher for pyrimidine nucleosides. Several anti-viral and anti-cancer nucleoside analogs are also efficiently phosphorylated.
Sequence:
MAEAASCARKGTKYAEGTQPFTVLIEGNIGSGKTTYLNHFEKYKNDICLLTEPVEKWRNVNGVNLLELMYKDPKKWAMPFQSYVTLTMLQSHTAPTNKKLKIMERSIFSARYCFVENMRRNGSLEQGMYNTLEEWYKFIEESIHVQADLIIYLRTSPEVAYERIRQRARSEESCVPLKYLQELHELHEDWLIHQRRPQSCKVLVLDADLNLENIGTEYQRSESSIFDAISSNQQPSPVLVSPSKRQRVAR
The following text describes a protein:
Function:
Degradation of glucosinolates (glucose residue linked by a thioglucoside bound to an amino acid derivative) to glucose, sulfate and any of the products: thiocyanates, isothiocyanates, nitriles, epithionitriles or oxazolidine-2-thiones.
Subcellular Localization:
Vacuole.
Sequence:
MARGYRFFIILSVISLFAETIDSRILDRHSFPDGFIFGTAASAYQYEGATSEGGKSPAIWDHFSRTYPERTKMHNADVAIDFYHRYKDDIKLMKELNMDAFRFSISWARLIPSGKLKDGVNKEGVQFYKDLIDELLANDIQPSMTLYHWDHPQSLEDEYGGFLSPKIVEDFRDFAKVCFEEFGDKVKMWTTINEPYIMTIAGYDQGNKAAGRCSKWVSEKCHAGDSSTEPYIVSHNVLLAHAAAVDEFRKCKKTSADGQIGIVLSPRWFEPYHSDSTDDKEAAERALAFEFGWHLDPVIHGDYPEIVKKYAGKKLPSFTVEQSNMLKKSSDFVGINYYTARFASHLPHIDPAKPRFKTDHYVEWKLTNHSGHIIGPGDERGLILSYPEGLRKVLNYIKDRYNNMPVYIKENGINENDDGTRPREEILKDTFRIEYHDKHFQQLHKAIVEDGCDVRGYYAWSLMDNFEWEHGYTARFGLYYVDFVNGLKRYPKDSVKWFKRFLNRSNGETKEVKEVSHEKSRSYGNKTLHELVQKKKKKTLHEQVSFDESAGFFVSFMAANQSTRDEEQNRCSFDSTYPTSIY
The following text describes a protein:
Function:
Functions as a glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm.
Sequence:
MGLICTRLASGVMAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGTGYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVLYHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYLCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLCDAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MAPLTAAMRSTPRIIVSNAFGFQRRAISDVTITRTGKPIIRNQGGRSSLGGHTATVFGATGQLGRYIVNRLARQGCTVVIPFRDEYNKRHLKVTGDLGKVVMIEFDLRNTQSIEESVRHSDVVYNLIGRDYPTKNFSFEDVHIEGAERIAEAVAKYDVDRFIHVSSYNADPNSECEFFATKARGEQVVRSIFPETTIVRPAPMFGFEDRLLHKLASVKNILTSNGMQEKYNPVHVIDVGQALEQMLWDDNTASETFELYGPKTYTTAEISEMVDREIYKRRRHVNVPKKILKPIAGVLNKALWWPIMSADEIEREFHDQVIDPEAKTFKDLGIEPADIANFTYHYLQSYRSNAYYDLPPATEKERREDREYIHML
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Required for proper cytokinesis.
Sequence:
MSESIDINVYSQTTIPNAMAELMDNHNKMEQISAYCKSLYANGDAAQAYEQTQGYAKNALLNVAYHIQTVGTHITSLLQLQTNEMEKLNIEIQTLTQRVRMIHDSTGTNVFSNQDAAKPYKSSLKNRKVDTEATKAPVKYVHKPISYGISASDINQNGVPPPLNHSNSSANLTSSSGHLAASSTSNSSTPSYQSPSYSSQPTISSGTPPPIQKQPPRVGNAPPPPSLSVPAAPPPPVMNVPPPPPTSQRPSSVNNNAPSNDFPPPPPPSSSSSGGDLPPPPSFGLPPPPTLGDDFPPPPPPPVGSYDFPPPPARPQSQFYDHNDFPPPPPPM
The following text describes a protein:
Function:
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
Sequence:
MNKRQTTINRIFKLSGIGLHTGREVTLEFIPRREFGIAFVYQGQLIPARYDMVADTRLSTQIAADGKSVSTIEHLMAAFYYSGITNCLVYIDGPEVPIMDGSAWEFYHEIWRAGVYEFPETGVYLKVLRPVEVSHNDAWVRVKPLNTLDITMTIEFRPPVGKQRKRLMDVENAVSIINSRTFVLHEEIEAIRKAGLAKGGSLDNAVVIGGEEILNPNGLRYKKELVNHKILDLIGDLFTCGYRMLGKVEANKTGHYLNNRLLREIFADPDNYAIY
The following text describes a protein:
Function:
Mediates Mg(2+) transport.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Sequence:
MNLGFLVGVFGVLILSHAAYSTIQYRGLLKIMEEEFSRPPINVILELIIGLALCMWAALTFPGKFLSIHPDSDENRAVFLPDNSDFMIFNHRGRLFPPQIDMKF
The following text describes a protein:
Function:
Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
Sequence:
MLPDGETPSCSETTASGTKLGTCEVCARKNAKYCCPRCEVKTCSLSCNKIHKLEVECSGVRDRAKFIPVNKFTNLDLSSDYRLLEEISRVVETSKKGRSSFGYNFTKGLLRLQQEALKRHITLKYLPRSFVRHKNNTTRFDFKSQVIEWRVDWVFVNCENLKISEDKVPENLRLSKILDKYLSKQGDEALQYYQAANLPGLRILLKAELKSGKKFYELDPSYTLRECLKNRVIIEYPTIHLVLKDQAIFYDIVDSDDEEDTKAELQKQIKSGQEVINKIIKKSESDDSLYESLRNLLFINEYSDEEQGSDEEAK
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MKSFTRNLRRFQTPRRNLHGISYTPKKVEGVSFAGRETPTATGSLSVVINAGSRYQPDAGVSHLLEKFAFKTTEERSALRITRESELLGGQLSTQITREHIILTARFLNEYLEYYARLLAEVVDATKFLPFQLTEEVLPTARIESELFREDILRVAMAKLHEKAFHRGIGNEVYLPASASPSISEIKDFASKAYVKSNFSVISSGPDVQKASDLCAKYFAVIPDGSPLKSAPTKISSGESRVYSKGTNYFCLGFPAPAASPELFVLSSILGGDAAVKWSHGNTLLAKAAGTASEYKATAVADLTPYSDASLLSVVISGSCPKAIKATASESFKALKSLSSNIPNDVVKSGIAMAKTKYLSAFEPVTLNAISASSLVSASKGSDAFISGFDKVTPASISKVVSSLLAKPASTVAVGNLDVLPYYDEL
The following text describes a protein:
Function:
Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (2',3'-cGAMP) from ATP and GTP and plays a key role in innate immunity. Directly binds some unknown ligand, activating the nucleotidyltransferase activity, leading to synthesis of 2',3'-cGAMP, a second messenger that binds to and activates Sting, thereby triggering the immune response via activation of the NF-kappa-B transcription factor.
Sequence:
MEKIIEEQAQDLEEACRDVPDVEVIHSGSGFEGLSLPQLIHGQTWNTDADHMIIKTSLKLQEVVKPEETGGERNIEEDQHVVRGKGSFTDAETDIAENVLFIYDASHAGYVHLSNKRPLFPTDSDSVREHCLQNSKFIDSSRKSVPFSHLYMRSKEGSIVGPSYSIQYTTGSFNVDRDFVYGLKCEQWPLQANEWILRDRPQSWPGFEQISAISDQGCHVVPVGSHMSHLREFEWRFSFSAAELILARSLADDQKLAYSVLKALIKSEMKSRDADVFASYHLKTCLFWLLEKRGINSWNKQSLGTNVLELLNFLIGFYDEGFVPSYFIGKNNMIDHRSPEDILKTCHALREIRDSVTQSFCRYIQYNQVLPVLFDTSLTQQLKKNPTKFLQNCKYNFLVMALAYILRPIKMVQMNISSRCLESAASLMKKAEILHKATREAGSQEYKELLSALSDALTPVENPTTNMVLSLLEEFLATDKMKVTESSAVALAVFNVFLALHPSHLHQGSETNPLEFHGYLVNPIFKDCFLWAAKVHERYCDAIYNFVVKKWVGGPHLITTDQEATKFMKLLMVILGKPTKQAGAVTGSLFRSSNEGQMFLLTRFLADYLLHVHLECAYVTFQATAFLMNKSVLSEIYLTINWGTYKPSQLRAIELVLSKQELQAELSEEDFTKLIKKQHELKTELSTG