lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MADSGDEDEEEYEEEGQDEYEKDGFIVDEEEEEEEEPEEEPQESSDEDSKAKKKKRKKRGEETYELDEDDYDLLQEANVTGFHRPPKADGKTKFKRLKKGGIGGEKGSGGIGLSDDDEEEDGGGRRGRTAEEELKRSLFGEDDGAAAEDVVEEEELDDEEEVDEDEMADFIVDEEEEEVDEHGEPSKHRKKKKKVKRKDFRQAPGINSIALQEAQEIFGDVTSLLEERRRRERDTLAGVDDEDRVDDDDDDGYGRSRKPPSQKLLEKQFEPSLLEEKFLTERDDRLRETDVPERLQILEEAVGALPTSDSAIRQAAEWIYDRAFGHLAVPVRPEFRHLSRDRDLISRQIANVLHLIHDDKFEIPFIAMYRREECFDLLKEASDDYEDEERPLVRTYAALWAVQQWDKKWLLLQRRKTALQAAYEKRIPSDIRDDPEKDELVDKILRALADAQADQAVDDCDAKFNLHFPPDEVEIVDGGFKRPKRRSLYSICRKGGLGVVAKEFGLAPDLFGENLQATYKRHDVEDKPISPEELAARFCSTNRPANEFWDVRSVLRGARHMVAVEISTEPAVREYVRGIYAERAVVSTRPTPDGNDAIDSFHQYAGVKWLLNKPIGAFDDAQWLLIEKAAEEKLLTVTVSLPKEPIATLMQDCETLYLSDGVSLTAQQWNEHRKQILHDAVVTLLLPAMEKEARMVLTTRAKQWLSAQCGLQLWSKVSIAPYVPPKAGDQDERIDDGPALRVLSCCWGPGNPATTFVMLDAAGEVMNVLHTGYLNMRATSAEQKKRKENDQDRLLQFMREYQPHVVVLGAANLQCRHLSQDIFEVIFKVVEEHPRDLAEGLDMIKVVFGDETIPSLYENSRVSQEQLPGQPGIVRRAVALGRFLQNPVTMVASLCGPTKEILSLRLHPMQNSLTNEELYEAVERVMVTVVNQVGIDINLAASHDWIFGPLQFVAGLGPRKAGAIQRAIQSAGRVGTRKDLYSSIRVMDRKVFINSAGFIRVRGSGQAASGMQHLDPLDDTRIHPESYQIAKNMAEAAFKEEAIQNDEEVDEDMLEMAVEHVMTNPVVLDTMDVEEYARSTQGRGQGRKIPTLRLIKSELQHGFRDWRKPYAEPSEEEKFYMLSGETEETLSCGRIVNATVRNVQQNRVMCVLESGLLAFIQKEDLSDDRDVEPSDKVSEGSIVTCRVKEVKLAKFLVDLTCKGSDLRAEHWRPRVQPDPYYQPDTTFLQREQDKVRKKKEEEKKKAFKPRMIVHPYFQNVSIDDAMKALAEKDIGDFIIRPSSRGPTHLSMTLKIHDGVFTHIDIAEGGKESRDLTSFLSLGKTLTIGEESYEDLDEVIARYVEPLVGYLREMLRYRKYKQGTKNEIDDLLRAERAANPKRIPYYFSVAHEHPGAFMLSYIRAVNPHHEYISLSAKGFRYRKHNFENIDKLVAYFQKHFNDPLPEAPRRAVAAMVAPRSPSSYSVGSYGYSAGSRRPSESGASGFDSRNSQWGDSRAGGGGWGSSSGWGSRGNSGWDKAVVRPSGDNRGSTSNWGPEPSPRNNWDKNGGAGRSAWDNSQPGAPSQWDNVTNSEGGAAGDGWAAVPGATPTSGSGWDAVPGATPTSGSGWMPGGHAGPRGF
The following text describes a protein:
Function:
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin (By similarity).
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MRSRSNSGVRLDYYQRIVHRLILAHQEPVTGLFPASNVNSHAWIRDNVYCILAVWGLSMAYKKIADQDEDRAKCYELEQSCVKLMRGLLMAMMNQKDKVEKFKMTQSPYDSLHAKYSSKNGLPVVDDNEWGHLQIDAVSLYLLILAQMTASGLQIVFSLDEVSFIQNLVFYIESAYSIPDYGIWERGDKTNHGEPELNASSIGMAKAALEAMNELDLFGARGGPASVIHVLADEAHKCQAVLQSMLPRESNSKELDSGLLCVIGFPAFAVDDAQLIHNTKDAILSRLQGKYGCKRFLRDGYRTPKEDPSRLYYERWELRMFENIECEWPLFYCYLILFHAFQSDKRAVEEYASRLEKIMVRSEDGILLVPESYAVPQDLVGFEYQKPGSQVREVVGRCPFLWGQSLFILGRLLQEGFLAVGELDPLNRRLGAQKKPDVVVQVVIIAEDNEIRDKLAEHDLHVQTIAEVAPIEVQPARVLSHLYTYLGRNRKLGLSGRKSRDVGILSTSKLYSLKDRIFAFTPQFADLSRFYIASDNELMIDILKGEINFLKSAWDLLGRPLVTLVLKRIHLDQDKIPLAMIQTMRKLKSGYINGTRVMLGSLKDFLNTSAITDLSFLGSTEDGYPDRLHPDVQTYLDEHLLRSFSNRSTMNLRGGQLRPRTLRRRMSCKGAIKKTRSINVDSDNLGMEGPSPLTERRLSSIVPPPWLQANKQSHVSVFATTPEEGPTSSPLSLGNDLIRENIYPVDPHHSRSAIDRRSEFVRQQEMPKILIQRHRAETNFADTEVEELIAMLRETENLEEQGDILQYLVDTQGLDFNTAGLGFKNKSEENATPNANNAGMLEEGRVVTVRDLLKGLYEKACQQKLWGLVRHTAGMLGKRVEDLAKAVTDLLVRQKQVTVGMPPNNEHTITAPLPEVELRQLIHDAYGDDESTAMLTQELMVYLAMFIRTEPQLFHEMLRLRVGLIIQVMAKELSRTLNCDGEAASEHLLNLSPFEMKNLLYHILSGKEFAVSSVARGNLSIVSCKSSRVSKKSQIGLGDPEGEDALIATIDDRQGQWLRRRRLDGALNRVPRDFYSRVWTVLEKCQGLAIEGRVLQQSLTQEMTPGELKFALEVETALNQIPQPEYRQLVVEALMVLTLVTEHNMVPSLGGVIYVEHLVHKANQLFLEDQRKVQGDATLCCAKIKDGKEQQQAASGMLLCGGAAYICQHLYDSAPSGSYGTMTYMSRAVALVLDCVPKHGEMECAIS
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase.
Subcellular Localization:
Cytoplasm.
Sequence:
MDVSRLEKLLAWGLEHGIRLPEHVKFCEAPGKGIAAFASDEVASGAAFELPHELILTSGLALEHFNKTRDGNMWLKLLLAKMRFGGGPVNVRGCDVAAKFEPYVACLPARVGSPLEWPVEMWALLQGTNLGKSVGQKLLEVVQQWRDMLAALGAELDTAVQAQAAAAAELLAAGVAEWPAFHARVAGGPATSWLSFQAFLWGHLMLTSRAFPERVLRSDCDESAVVLLPVLDLLNHSTDARVEWSGKDGFTIRQLQPLRQGQEVCNNYGGKSNEELMLGYGFAIEDNLFDHVALRVCPPAATVQAMLDAGLKLPTLDDYTTYAFERHPATSSVHDASAYSKGVLFLLGRSNVALEQLLDLFAFQEAAAEECHKALRCRLQAMQNLIELLRGRLHVIQEGEMAADEQETAAKSYPQAMATVRIYRKQQQELLRAAVKTLKRWEKETLAAIKEKTVAFKNVTKHDPGFVDELLPALFSSDVEFENYDDILLLWIILRGKSSVETPKRFQSLFAAYVTYARGPADLSEDLQTMFESKYRAWFPKGSKQVSLDEVLDAASFFMRHSYVRASTGESIIIVE
The following text describes a protein:
Function:
Mediates the translocation of RNA and DNA across the lysosomal membrane during RNA and DNA autophagy (RDA), a process in which RNA or DNA is directly imported into lysosomes in an ATP-dependent manner, and degraded. Involved in the uptake of single-stranded oligonucleotides by living cells, a process called gymnosis. In vitro, mediates the uptake of linear DNA more efficiently than that of circular DNA, but exhibits similar uptake efficacy toward RNA and DNA. Binds long double-stranded RNA (dsRNA) (500 - 700 base pairs), but not dsRNA shorter than 100 bp (By similarity).
Subcellular Localization:
Lysosome membrane; Multi-pass membrane protein. Cell membrane. Note=Mainly localizes to lysosomes and only partly to the plasma membrane. Lysosomal localization is required for SIDT2-mediated intracellular degradation of endogenous RNA (By similarity).
Sequence:
MFALGLPFLVLLVASVESHLGVLGPKNVSQKDAEFERTYVDEVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGMFQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVSRMDDFVLRTGEQFSFNTTAAQPQYFKYEFPEGVDSVIVKVTSNKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFAEDEPVDQGHRQKTLSVLVSQAVTSEAYVSGMLFCLGIFLSFYLLTVLLACWENWRQKKKTLLVAIDRACPESGHPRVLADSFPGSSPYEGYNYGSFENVSGSTDGLVDSAGTGDLSYGYQGRSFEPVGTRPRVDSMSSVEEDDYDTLTDIDSDKNVIRTKQYLYVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDLCALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSIIHIIATLLLSTQLYYMGRWKLDSGIFRRILHVLYTDCIRQCSGPLYVDRMVLLVMGNVINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF
The following text describes a protein:
Function:
Heat shock protein required for pathogenicity. Mediates thermotolerance and adaptation to oxidative stress and ethanol-induced stress. Required for invasive growth and filament formation under various filament inducing conditions. Plays a role in the capacity of damaging human-derived endothelial and oral epithelial cells during infection. Potentiates resistance to antifungal drugs, as well as resistance to killing by human neutrophils. Plays a major role in trehalose homeostasis in response to elevated temperatures. Regulates CEK1 activation by phosphorylation in response to elevated temperatures.
Sequence:
MSWFGFFDPDFDDFFGRPRKYATEVPPNFNPRKIAQGDNGKGQQVSRYGAGAGHPHRALARRDDFFDDFWKNFSSGKYFVGFDDNVKTTEESDKYVVSYDQENLSPDEVNVDFDKQENELIITVTQETEKDGTKKSSTFHSNLKFEKPVNFDDISAEIGEQGVQVTLPKVHADHEKIVNIPISKAAAKK
The following text describes a protein:
Function:
Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.
Sequence:
MLAGLRCRTTSILSASQHYQCRHFFSFPSNEPTTFSVTQRFNYPPGLIYGVVSDVQHYSEFVPFCEGSTITKTDGDGNPVEAVLKVGWNQFNEEFASKIECVKDKSVVSSAPDHSMFNVLYSKWTISPSQISENACNVKLDLEFQFKNAMYNMVSSQFAPAVSQVMVDAFTKRAHAVALQEKRKVN
The following text describes a protein:
Function:
Negative regulator of sexual differentiation. Acts by repressing the transcription of meiosis-inducing, ste11-regulated genes.
Subcellular Localization:
Cytoplasm.
Sequence:
MVVSSPSVSLLHSPVEKLSAQLEKTTLLQDIPPGSLSENDNSTTFIKPPLETASSSTPIPSSSSSGVLNPSSVRGKPVACLFVASLNSSRSEEELTATVKDYFQQWGPLLHVKVLKDWLQRPYSFVQFQNTDDASKALSEAQNTILDGRHIRIERAKVNRTIRISSAPHQPYITKKDIDNLLEPYGEVEDVTEIPDQSAFLVRFVYRDEAIAAYTALKHSAWPVLWAENVTYQNGHYKKKGSSPFSPPNAHSRRRKSQGKDQSNTPVIKAPAPIPFSVSSDPPSTMGRSNSAVQSPSYFAHSLVNSTEFSTPNESLSSLPSILPSIPSLESGKAELPTDGSFEQPGYPMNPSMMFAAMPPPIDPYSIFVGQLDPVNCTHYLLVDLFSKYGKVIDCKIIHQSKKPAFAFLRFDSQQAAYAAVCGKTRSPHQKKPLRVEFRQLRPMQQFSPQYQYPSYPYPMFPAPFSPPRNAMMPIPAPMDQFSTFHQSMATLPPGAVPTSIPQSYYPIYSPEMAMPQSYSPMYYTHNPPMDGN
The following text describes a protein:
Function:
Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Potential role in cross-linking filaments or anchoring other molecules. It is essential for growth.
Miscellaneous:
MISCELLANEOUS: Present with 279 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Tightly associated with the nucleus. It is present in a granular pattern that excludes the nucleolus.
Sequence:
MDEASHLPNGSLKNMEFTPVGFIKSKRNTTQTQVVSPTKVPNANNGDENEGPVKKRQRRSIDDTIDSTRLFSEASQFDDSFPEIKANIPPSPRSGNVDKSRKRNLIDDLKKDVPMSQPLKEQEVREHQMKKERFDRALESKLLGKRHITYANSDISNKELYINEIKSLKHEIKELRKEKNDTLNNYDTLEEETDDLKNRLQALEKELDAKNKIVNSRKVDDHSGCIEEREQMERKLAELERKLKTVKDQVLELENNSDVQSLKLRSKEDELKNLMNELNELKSNAEEKDTQLEFKKNELRKRTNELNELKIKSDEMDLQLKQKQNESKRLKDELNELETKFSENGSQSSAKENELKMLKNKIAELEEEISTKNSQLIAKEGKLASLMAQLTQLESKLNQRDSQLGSREEELKKTNDKLQKDIRIAREETVSKDERIIDLQKKVKQLENDLFVIKKTHSESKTITDNELESKDKLIKILENDLKVAQEKYSKMEKELKEREFNYKISESKLEDEKTTLNEKISNLAAENSQLKNKIEDNSTATHHMKENYEKQLESLRKDIEEYKESAKDSEDKIEELKIRIAENSAKVSEKRSKDIKQKDEQISDLTQNLKLQEDEISSLKSIIDRYKKDFNQLKSEQSNIQHDLNLQILNLENKLIESEDELKSLRDSQKIEIENWKRKYNNLSLENDRLLTEKESASDKEREISILNRKLDEMDKEKWNLQESKEKYKRELQKVITANDRLRREKEELNENSNNIRIMEDKMTRIKKNYLSEITSLQEENRRLEERLILNERRKDNDSTMQLNDIISYYKLKYHSEVRHNNDLKVINDYLNKVLALGTRRLRLDTRKGEHSLNISLPDDDELDRDYYNSHVYTRYHDYEYPLRFNLNRRGPYFERRLSFKTVALLVLACVRMKRIAFYRRSDDNRLRILRDRIESSSGRISW
The following text describes a protein:
Function:
Glucosyltransferase involved in the biosynthesis of the non-bilayer-prone membrane lipid alpha-monoglucosyldiacylglycerol. This is a major component for maintaining a certain anionic lipid surface charge density, for balancing the bilayer to non-bilayer phase equilibria and for keeping a constant lipid bilayer spontaneous curvature (curvature packing stress). Catalyzes the transfer of a glucosyl residue from UDP-Glc to diacylglycerol (DAG) acceptor to form the corresponding alpha-glucosyl-DAG (1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol). It can only use UDP-Glc as sugar donor and DAG is the preferred substrate.
Miscellaneous:
MISCELLANEOUS: PG could also protect the enzyme from proteolytic digestion of the proteinase K, possibly by orienting a lysine-rich face toward the membrane.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=The enzyme binds the membrane surface via electrostatic association with anionic lipids and is accompanied by hydrophobic interactions and by a conformational change induced by nonbilayer-prone lipids. The enzyme is supposed to be located on the cytosolic side of the membrane.
Sequence:
MRIGIFSEAYLPLISGVVTSVVNLKEGLEALGHEVYVITPIPSKDKFENDPSVIRIPGWVIPRKSLKGFRLVLFVKRYVRKMRKLKLDVVHIHTEFSMGKLGLAVAKKERIPSVYTLHTSYQDYTHYVSKLLTRFAPNAAKKLAGKINNQYTKNCHMTIVPTKKIYDKMIRLKHDGEFTIIPSGINLKPFYKSSYTSEQVQALKDKLGIRNDEFVAILVARIAKEKSIGDLVEAFVEFYKSYPNSRFIIIGDGPDKPVLDKLIDSKKASKYINTLGFVKNAEVGLYYQIADVFLNASTTETQGLTYVEALAASLPIIVRYDDVFDAFVEDGKNGIFFNKNEELVKHLIHIRQNPEILGTLSKNAEISTKPYAKEVYAKSCETLYLDLIDKNNKKLNKK
The following text describes a protein:
Function:
Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2) (By similarity). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles (By similarity). Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts (By similarity). Regulates chondrocyte proliferation and differentiation (By similarity). Inhibits cell proliferation and tumorigenesis. Signaling is mediated by MAPK, p38 and JNK pathways (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell projection, podosome.
Sequence:
TSKPVQNRELQGYESTDFXGYFKGGLKYKAGGVASGFNHVLTNXLSAQRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGSEIYQWFGSSCNKYERLKASQVATGIRDNERNGRSQLIVVEEG
The following text describes a protein:
Function:
Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MRGLFAAAALLVGAQAAIDPIVIKGQKFFYKTNGTQFFMKGVAYQQEINSNTTQSAESTIQITDPLADATACKRDIEYLKKIQTNTIRVYAIDPSKDHKACMNALADAGIYVVADLSEPKNSIIRDDPGWTTTLYERYTQVVDELMKYDNTLGFFAGNEVSNQPNNTIASAFVKAAVRDTKAYIKSKNYRPVGVGYATNDDADIRENLSAYFDCGNKEDAIDFWGYNIYSWCGDSSFQESGFDVRTKEFEKYNVPVFFAEYGCNTPRPRLFTEVGALYGKQMTGVWSGGIVYMYFEEENKFGLASINNGKVSTNKDFENLSKGDRQGHSRRRQECPSTTLPNTAAATCPKDHPRQVRRPSLTLFLLRPMLLSVPAWLRPSAALLQTTSKRRTSATCSASSVVRRRASTARASTRTLPPVLTVRTACAPPRTSFPSPSTPMPRLSPMAAASRARLPPRPLSPLLLPLAALLCSRLLVLRVPALSAVVPRLVRLVRLLPALPVPLPVPLQVSRCLRSALAHSAWASTFSEPWLPVWL
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MENTYVGQRDYRFNVNQLSYRGIRRRKWGKWVSEIREPGKKTRIWLGSYETAEMAAAAYDAAALHLRGRGTNLNFPELVDSFPRPESSSSEHIQAAAQDAALMFKPGRLSEPALESGQGLSRVGLSPDQIQAINESPLDSPRMGWMQDLEVADYEELYGQFFGQHDRDEFFEMQQFQSIWNSNN
The following text describes a protein:
Function:
Acts as a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. NOT2 is required for the integrity of the complex. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSLANRLSHLNITGGNDFKASIGPSVGRQNEATNPWSSTSHSLENSAATVVNELQTTKEQKTPEQSTTANPLFPGNDFSDFNNHKSKLLGVITGKSTPSSQAEKSDTTNSKTGSTEELTETPADENAKQYMLESLLPIIRMEDSEMSTLQLGCDLAALGFDLAPVEEDRLISTNLFSPWAELNTKKPVSQPMFKLPACYKNVNPPPAISKIFQFSDETLFYIFYTMPRDVMQEAAAQELTNRNWRFHKELRVWLTPVPGMKPLQRTPQFERGYYMFFDPIHWKRIKKDFLLMYAALEDRAQSAVHS
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MENHFSATSRPSATPRMCTTASAVGAAASAAAAAGNNNNNSNSSSNNNATTGNNLSVSTAAGGATNAAATAQPIQVIPMPMLPTGAAQIIIGQQPQGQATATGLQPQLIPLQANQIMLQAAQQQPQMQVMQLPDGQTIFYQTPTIAALDPNAAANAAAAMAAQPTPHYLNINGQLVQINPAPSANQAAPTAGQQIIMVPQTAMAAVNAAAANAGVGAGVGTVVTQQQQQQHQQVQSQTQNQQQQQQQQTVAAVAASAAVNNISADVSTSTTGTNTNSEDESSKGEADEEPLYVNAKQYKRILIRRQARAKLESRIPKERCKYLHESRHRHAMNRARGEGGRFHSAQEKGDQDSSGPEGGSMPMASSGGVTLSRGTARAPPKLIAPHQTPSITITAIKSE
The following text describes a protein:
Function:
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Subcellular Localization:
Nucleus.
Sequence:
MSILRSPYQCLKQCGNYLVAARGSSIDTFDIKNGSYLSTWKSPVPESMSRSKTTEEETQTKNEDQNSETATPEFILESSAPPAKRRKLSITKESGENTGVVQQSKKKTKNSSPKILEPSPITALTITRDLQHVIAVTGEDKTIRVLAWEDTVEKGLRQISDRTMPKRPCALAITDDCNTIISADKFGDVYSLPLIPSPLVPSATENASVQKQAPKMFQPSASALTVHSARNLKALEAQKKQSNKVSEKTGPDFEHKLLLGHVSMLTDILVATLSGRQYILTADRDEHIRISRGIPQAHIIENFCLGHIEYVSRLCIPPTRPEILISGGGDDDLYTWNWLNGSLLSKTNLKSQVEALDTEKQSAQEAESKKIAVTGVYHARDEVSNQDIIIATSEGVPAAFIYFLTASNQLTHTQTLALPGNALSCTFSNPDLSSPFSLIISINNIHEPSSITTLKDANSSVANPLQFFKYENEKFVSVQQDGFAPQDSEGILDDQQKNNLCGLLYNVGNLRKMEDEE
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MAEPDDLFTLKNQLWVGNYQNALSEGAMLTHVSEALRHERDVYVYRAQLALGNFSVVLQNVPDTGHTPIALSAMKLWATYLSGQGDKEMIDLTLKEWLGDPTSGENAHLLLIAGQIYAREGKLSDALSALTRGGSLEHMLYIVHLYLQMDRVDLAHKTVLEMKRIEEDSTLTQLAQAWTLTLQGGDKADEATLHFQELADRFGATPLLLNGAAAAFMALRNHTEAERLLLEAAQKDPSNEDTLINLIAVSAHLNKPTHQYILQLQQVAPASAWLENYVLLDRGFSEMAATFA
The following text describes a protein:
Function:
Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC, yielding the 53 kDa 'open' conformation intermediate protein, which is committed to further processing. Required for virulence in invasive pulmonary aspergillosis (IPA).
Sequence:
MSRTSSAPSQKSLISRALKAERDVITASSQSQALDAAIDAAEHYMKALALTSSSKDRNVLDAKCKEWLTRAEKIKGSEDWRSVAQSRRSRLRTPASTRKLTTREDIILLQGAKLNGFIFPPWKAEPSLTEFETGTNGDVLFTDKPDLHLSNLQRDIFAGWKRPHELLSGQVDDAGMPLNPVMTVSGNTDLVQDVLTDCSVVASLCATTSRSERGLDDTLLPIVYPCIHNSMKSDISPSGKYIFRFYFNGCFRKVVIDDRLPSSKTSRSLYMIDRNHRNFMWPALVEKAYLKLRGGYEFPGSNSGTDLWVLTGWIPEQVFLHSDEVTADQIWSDLFKSFHSGDVLLTIGTGKLTEREQKELGLVSEHDYAILDMKELKGRRQFLIKNPWAGTDAVYPALFADPGPFPNSPFLSPGTFWMDCEMVLQNFENLYLNWNPGIFAYQEDIHFTWDLSTGKGMAGCFVKNPQFSVYTERGGVVWLLLGRHLRTIESRASEEDERFGFISIYVFKGGKRVALSDGALHRGPYVDSPNTLMKLDVPPRSTYTAVVSEESLPRVSQNFTISAFSDSPVRISHAPNKYICVTKVQGSWTPTTAGGNAESARYSLNPQFSIVLSDPTDISIVLEPSDQELATHVKLFWSGGKRIARVRSRDIVADSGDYRRGGSLVEKQDLDPGEYTIVVSTFAPDQYGSFTLWVSTNITCEVTQLPSEAAGRRAVLSDIGVLLPGQDRMLAPLTTPRLTRVKLIARSRESRIGNRPVGPSPLLMTVELGQGPYKEILATSEDGDHSDSISGVRVEDFDLQPGLEERGGVWIVLERIGGPGGQVEDHFEVEALGEERVEIGEWIVEDA
The following text describes a protein:
Function:
Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.
Subcellular Localization:
Nucleus.
Sequence:
MQYDDVLGREAENELSSTQPDRPAVLASRNSHSRQEKRDEDIRAGLVGSMKIIAGGKDYMDEQETDEVFLNLAKDYKGSQSWTFGRAGSANFVVARKARLSKIHFIVEHTGGTKQRAGTVVIRDVSLNGTSVNGRYLGRGNSALLQNGDVITVGAMEGVATQDNPDETKFIFTHHMGTEVPYDENSFHAKYDMSNDLLGSGAFANVYKCVARDGGPVRAVKQIMKSKVKNPGAVQREIRVLKRITHPGVVQLIDHFEDDQCHYLVMELMENGDLMDFISEFGAIPEFVTREIVKQVLETVRDFHAMGVSHRDIKPDNILVFQDDPVIVKVSDFGLAKVTQDSILNTFCGTMAYIAPEILLSRERRKANSADPGCYSNLVDMWSIGCLCYVLATGYLPFDGTSHEAIVKAITAGTYCQKPLNDFNISPMGRDFIKCLLTVDPEERPSAIQILRHPWFSDDSVRLRVTEGEAGDASPQATLDSDKFQDIRRATIIGDGPDPNSMPPLMEDNDSEIRSRGEPISVEGLVLTDNVETRIGGAASEMARDAVMEERRQRELLNEKDSMDSDTDGGVQAHDRPVDSNFSWVNPDRNGTGSEEKHETPAEMEARIRKELERKIRNEVESRVRAENQSILQAQAEQAARIRAEAEAQRMAEADTDNDESDVEDGSVVKIPSASKTRRARPNTWLNLKSLPNTIHEIEFDITGDNYRIGRVVSDNQIVIDKAPISKEHCIFEKRIMTDPKLDGFFRIFLHDFSRNGIRVNSEKIGKGNTVQLQHGDIIHLFLDPQVEGGSLSMLVNIESPEYSYHDGTSRPGKLMRTQDISPHVLAEQTERELKRLEQARAELARADFNSRAFNGVVTTPVRQVSRQSSRRASRSGVKRDGETLQSGRQVSVRRTEY
The following text describes a protein:
Function:
Interacts genetically with prohibitins and thus may be involved in the mitochondrial lipid metabolism.
Miscellaneous:
MISCELLANEOUS: Present with 937 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MLNLCHALRGVRQFSCSVIVKVKCASCSIKLQDQDPSKPGYYTKPKSLPDSKLNPDLQDLKYLLFSQDIQLSKQATQNDPDLKTKRDLLLRVICKRCSNALHHNNYNPEEFPESTLNDILNYVPRGSNVMHIVPFVEFPLHLDPNVLKRNDLDTTLVLTKSDQVFKDKNAVSKKVPIFMKQFLKNTLRIDSNKTFAISALKNWNISMFYNYFKNYTYLLGNPNVGKSTLINTLLQKYLGYKVKIDSTGKINSPSEEVMQEAFTNPKNFFKIQAAGVSHIPNLTRSVQAYQVGGKILFDLPGYSTSTSRLRLEELIDERWLQRLRKTDLFNRKHIKQKTYESMKGTSQGGCYTVGGIFYLVPPKGSINQIVKYIPGPSKTFKNIEKGIDVFNSCNSSSGTHPLSRYCGIKSVICEKSQYKRYAIPPFIGSIEIVLKDIGYILLRTTGRYEFKGLHEIWIPRGIQVGIREPLENLIESGYQRYIETNGKESSCPRDRPIISSLYEMAPDEADTLNAVKKSYLEKTEKDLSARRFVDDDPYDLVQHLEKKKNPYWYYQW
The following text describes a protein:
Function:
Has no transcriptional activation activity.
Sequence:
MESKGRIHPSHHHMRRPLPGPGGCIAHPETFGNHGAIPPSAAQGVYPSFNMLPPPEVMEQKFVAQHGELQRLAIENQRLGGTHGSLRQELAAAQHEIQMLHAQIGSMKSEREQRMMGLAEKVAKMETELQKSEAVKLEMQQARAEARSLVVAREELMSKVHQLTQELQKSRSDVQQIPALMSELENLRQEYQQCRATYDYEKKFYNDHLESLQAMEKNYMTMAREVEKLQAQLMNNANSDRRAGGPYGNNINAEIDASGHQSGNGYYEDAFGPQGYIPQPVAGNATGPNSVVGAAQYPYQGVTQPGYFPQRPGYNFPRGPPGSYDPTTRLPTGPYGAPFPPGPSNNTPYAGTHGNPSRR
The following text describes a protein:
Function:
Component of LSM protein complexes, which are involved in RNA processing. Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by promoting decapping and leading to accurate 5'-3' mRNA decay. The cytoplasmic LSM1-LSM7 complex regulates developmental gene expression by the decapping of specific development-related transcripts. Component of the nuclear LSM2-LSM8 complex which is involved splicing nuclear mRNAs. LSM2-LSM8 binds directly to the U6 small nuclear RNAs (snRNAs) and is essential for accurate splicing of selected development-related mRNAs through the stabilization of the spliceosomal U6 snRNA. Plays a critical role in the regulation of development-related gene expression.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDGGAGGNAGGGGLSTAKTPADFLKSIRGRPVVVKLNSGVDYRGILACLDGYMNIAMEQTEEYVNGQLKNKYGDAFIRGNNVLYISTTKRTLGDQ
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MTKPILGMAGKKKSKNLPYPEESVPRDREKYMTLGDHLEELRMVLIKSLIVITVIMGISLCFGEEIHKILTQPYKNVLGPQATFFQINLMAPFMIYLKSSFMISILLGLPFVLFFLWSFISPALDSKADRYGKFLIFFSTLLFWFGIWLCWTEAFENLLRIFLVNFRPLDIEARLPIDEYYEIFFNIHLIFGLSFQLPIILILLGGLGIIHSSFLLSKWREAIIILAIAAAVLSPGPDLISMLFLFVPLTVLFIVSIVLMKIIERE
The following text describes a protein:
Function:
Glycosyltransferase involved in mannan biosynthesis.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MGVDLRQVVAGILTITMFVMLGQMLHRDYFDSLQEKAQGDAQDIEFEGSKVSVKDGLVGTVEGSKGLWMEDNTDLTPCWPTLLSDDAVSSKGYVTFSLTNGPEYHISQITDAVMVAKHLGATLVLPDIRGSKPGDERNFEDIYDADKLIKSLENVVKVVKKLPEEVSLRNMAIVKVPTRVTEDYIKEHIDPIFKSKGNIRVASYFPSVNLRKSSQDGETDPVACLAMFGSLELQPEVNAVAESMVERLRTHSRKSGGRFIAVDLRIDILEKKNCHTTGVVGSKTCYNAQEIALFLRKLGFASDTTIYLTQPRWDSSLNILKDIFPKTFTKEAIMPASKRSKYLESVSSEYENVIDFYISSRSDVFVPAISGLFYANTVGKRIALGKPQVLVPAEISETSGLATDFISPYISKKNHLAYSCFC
The following text describes a protein:
Function:
Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
Sequence:
MIIKILLLIISISLFLNISIGIDENQIWKSCGTPQDIFHINSIVVKPTPPVKGKLVKVNVNGTFIKDVVAGEAKIIAKYNNIMTLYNETNDLCSPTAQAIIGNCPFKKGPTYLHSANFTIPASAPNGYYSGNILLTDNFNNTITCINVAFNLQ
The following text describes a protein:
Function:
Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MVSVFNDILFPPNQTLSPTSFFTSPTRKFPRSRPNPILRCSIAEESTESRPKTGDSPPPPLMEALAVWHRPGPRHQARQCQHCWGDSRARDRVGGGNITTMESGGYLWEEGPNSFQPSDPMLTMVVDSGLKDQLVLGDPDAPRFVLWNGKLRPVPGKPTDLPFFDLMSIGGKIRAGFGVLGIRPPPPVEEFVRRNLGDDVFERLIEPFCSGWSIDLRLPKPKGQTVGSFRKGLIMLPDAISARLGNKVKLSWKLSSISKLDSGEYSLTYETPEGVVSLQCKTVVLTIPSYVASTLLRPLSAAAADTLSKFYYPPVVAVSISYPKEAIRSECLIDGELKGFGAIYSSSLFSNRAPPGRVLLLNYIGGATNTGIYQSFSGKLQGWFKELIIFTSGLFGCFKQLRPNGLVSNTDSELVATVDRDLRKILINPNAQDPFVVGVRLWPQAIPQFLIGHLDLLDVAKASLRNTGFEGLFLGGNYVSGVALGRWVEGA
The following text describes a protein:
Function:
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MFVVIFGRPGCPYCVRAKNLAEKLKGEVADFDYRYVDIHAEGITKEDLSKSVGKPVETVPQIFIDEKPIGGCTDFEALMKEQFGIVA