lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Sequence:
MEVEDSGGVVLTAYHSYARSQPSSSEPRCAPRATASHPGSRKSIPRCRRINRMLSNESLHSPAFTRSNSQASIDSTSMEDFLREIESIKENSMGGQEEQIPAEVKPVDEGELEAEWLQDVGLSTLISGDEEEDGKALLSTLTRTQAAAVKKRYNTYTQTMRKKNKQSVRDVRDIFGVSESPPSDPCDSHTAQLDGTQEEKELPGVIKTSGSLTDDASLNSTTLSGGSQDEEGSFIVPRSGSVSILETIPALPVHSNGSPDPGQSVQNAVSDDNYLEKNIVPETEELSFEVSYSEMVTEVPKRNKFKKSDFKKEDYALTKFIVQKTRFGLTEAGDLSAEDMKKIRHLSLIELTAFFDAFGIQLKRNKTEKVKGRDNGIFGVPLTVLLDNDRKKDPGVKVPLVLQKFFEKVEESGLESEGIFRLSGCTAKVKQYREELDAKFNADKFKWDRMCHREAAVMLKAFFRELPTSLFPVEYIPAFITLMERGPHIKVQFQALHLMVMALPDANRDTAQVLMTFFNKVIANESKNRMSIWNISTIMAPNLFFSRSKHSDYEELQLANTAAHIIRLMLKYQKILWKVPSFLIMQVRRMNEATMLLKKQLPSVKKLLRRKTIEREVISPKTSKVLQKSPSSRRMSDVPEGVIRVHAPLLSKVSMAIQLTSHTKAKDILAKFQYENSYGSSECIKIQNQRLYEIGGNIGQHCLDPDAYILDVYHVNPQAEWVIKPQSSF
The following text describes a protein:
Function:
DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.
Sequence:
MALSELEKKRQENIRRNQELLKKLDLDSISDSIKKEVDNKSFSSPSSQKRRKTTKKPVIKKEISEPSRRSRRIAGIKSELEDPKQAARIREEEELKQHRKQELERLKRTRLFGDFKLIDLITNKKGDMIFEKNVMDRKLSHIGLDSKVEEKKNEEDKEDEEEAINIDENNRVLQLVQSLGDKFSAGDFYEEIRNSQTNGNSKDKSLDAKRKEFDNLNIYPRFDPLDIKICHNRITSMFFHPSTTNRIVVGGDTTGNVGIWLVDEQNNDTKEEEEDDDDDEPSISILQLHGRNVSKIMTPTFSPEKIYTSSYDGSIRVLDLNKLTSTELLYLNEPGAREDIALGVSDINQCQDSSVIFMTTLDGEFYQHDTRTPFNTRQRHHLATKDLLRLHDKKIGGFAVNPNTNYQIATASLDRTLRIWDLRNVNKSVYSEFENQKSPHMYGNYNSRLSVSCVDWNQENRLVCNGYDDNICLFDYSGGSKLDNELPVITEWKSDFVPSTKSSEESELLPNNLTPFTKIKHNCQTGRWVSILKSHWQTNPADGVQKFIIANMNRGLDIYNQDGQILAHLNEQVGAVPAVCTLHPSQNWAVGGSASGKVYLFE
The following text describes a protein:
Function:
Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit Polr2A/Rbp1 and Spt5, and (2) degrading the exiting nascent RNA transcript via endonuclease activity. The integrator complex is also involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5. Required for the normal expression of the Integrator complex component IntS12.
Subcellular Localization:
Nucleus membrane; Single-pass membrane protein. Nucleus.
Sequence:
MDRGKGSGSNRSQKKVPLGGELFALGKSVRDDSKSKILPIKGMSSSDRKREASTALASSSKRFRGNLKDAGAPDMSSGSSQCETWEQFAVDCDLDTVVETIYAALEQNDSETVGRLVCGVIKQTTTSSSRSKVDNIALLALIYVAKVQPSIFCTDIVACALLSFLRREANVKMRYNTNLHILFANLLTRGFMEISQWPEVLLRIYIDDAVNERYWADNELCAPLVKNICAAFKTRTPHISLLRWDVSSSLPSGQAHRDSMTVDDDSGDNSTQSLDASPLNTESEPIPDAMCTTKSRFSDAVVQKHVSDAIRDQLNKRQQQDNYTRNFLKFLCTTSGIAEVRCLSISRLELWIHNGKLVKFAQQLLSYICFNIKGRNTQDNEVLLVLVKMRLKTKPLINHYMSCLKEMIFLQPEILSTVMKLVVQNELSNTRNPNNMGMLATMFQTSADQSAATLAEIYQEFLLQRDDCLRTLRVFLRELVRMLRFDVNLVKFCKTFLSEREDLTPQIEMFEFKERIFNSMVDIVCLCMFLSATPQAREASLSLKTNRDTKNNHALLKLYNQMSQIQLDTVSWMYETVPTLFKIPAAEYHQALHKLLLLDSPEQYSRCDQWPSEPERGAILRIISETPIHEETLLRIILIGITKDIPFSIANTFDVLLLVIKRVSGMKATNIPAVQANKFDIIDFLFSMSEYHHPENIRLPAEYEPPKLAIIAFYWKAWLILLMISAHNPSSFGAFCWDHYPTMKMMMEICITNQFNNSSATKDELQIITMERDHILQFETYLAAQTSPHAVITEETAILITQLMLMDPMGTPRKVPSMVLDQLKFLNQTYKLGHLFCRCRKPDLLLDIIQRQGTTQSMPWLSDLVQNSEGDFSHLPVQCLCEFLLFNAHIINEENSRDAELVNFLRNLIFDGNLSHQIVCELLDYIFRRLSSTVKQSRVAALSGLKIIFRHSGDFENEWLLKSLQQIPHFYEVKPFIIPQLRAACQVENCPELIMAYIQFITAHTLNDPVNEMLDHVIDMAQLIVERSTMFQHIIISQEDYDYVPDENRIQTLKCLFVMFNNYIIKLREYHEPYEWTEYPDLLMVQFDDGVQLPLHINIIHAFIILLTYSNSNMPESIPILDYWFPPGRPAPVAFLPSMPQEQVQLLPDWLKLKMIRSSVDRLIEAALNDLTPDQIVLFVQNFGTPVNSMSKLLAMLDTAVLEQFDLVKNAILNKAYLAQLIEIQQARGAKNGHYTVQALDLHSHSQTVPDLPKISVVIQEAVEIDDYDSSDSDDRPTNFLATKEVAQTILTQPDQLTESRSDCRSLIQKLLDMLASPNSNRADVVNAITEVLAVGCSVTMSRHACTFLRTFFSCMLHSDKYHILENALQKNLSMFKHTFADSSLLQKSELYHESLVFMLRNSREIYAQQFKANTALVARKRIVRAIVQSFDQTKDSKTVAKSKSDQLFHNGLFIDWLSEMDPEIVSTQLMKERFLFSKSCSEFRFYLLSLINHQTNWDTIERIAEYLFKNFHEDYDYATVLNYFEALTTNPKLWKGRDKYMSKNVRPDAFFMLRTSELEPFSHFILHEGLSEVKLDSKNYDFKLCSRMNLLFKLTEKRRDLMVKVMEHVEKSSVSDYLKLQVLQQMYIMYPRIKFLKPGKTGEQAYKLQNLKGCQADKVSNNLITCLGSLVGKKDFETLSTDTELLLRKLAASHPLLFLRQLGVLSSIMQGRAQLSMKALREEHHFHRFVQILRTLELLQPTIFEEAYKNEIQNTLSCYFNFFKHHSNVKEACQMLNKFVQMLQAYINYNPSSALLFIEQYVGILKELAAKYTSLGKLQVLVQAVALLQHKSHSATELDDEEVKYEYDLDEHFDVKPSASKPVVTEDPIEVNPQTPIDPSSSRGPLSVLTLGSYSRSNYTDISPHFLDLVKIIKQSNTEDVVLGPMQELECLTSKRFVFINELFERLLNLIFSPSAQIRSIAFIILIRHLKHNPGNSDINLCTLNAYIQCLRDENSSVAATAIDNLPEMSVLLQEHAIDILTVAFSLGLKSCLNTGHQIRKVLQTLVIQHGY
The following text describes a protein:
Function:
Lanthionine-containing peptide antibiotic (lantibiotic) active against S.michiganensis subspecies sepedonicus strain 2136 (MIC=30 pmol/ml). The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
Subcellular Localization:
Secreted.
Sequence:
MNDILETETPVMVSPRWDMLLDAGEDTSPSVQTQIDAEFRRVVSPYMSSSGWLCTLTIECGTIICACR
The following text describes a protein:
Function:
Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells (By similarity). Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1 (By similarity). Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF-alpha through a mechanism that partially involves suppression of NF-kappa-B (By similarity). Also functions on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils. Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6. Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13 (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MALLLTAVIVLICFGGLTSPSPVPSATALKELIEELVNITQNQKVPLCNGSMVWSLNLTSSMYCAALDSLISISNCSVIQRTKRMLNALCPHKPSAKQVSSEYVRDTKIEVAQFLKDLLRHSRIVFRNERFN
The following text describes a protein:
Function:
Plays an important role in the control of DNA replication and the maintenance of replication fork stability.
Subcellular Localization:
Nucleus.
Sequence:
MEDEEFIIKTPINKNKRRNVVLDDEDDNINISINNIGDIDLDVEDIKTPSPKFTRNRLKKKVLVSPSTKSNNSSTNNSPENNNKHIISPLSPLSPKVRKVLQQKTASPKKKSPIKTPNKQEEEEDYNFMNNDEEISQYNNYEFENNIDQQEEQEQEQEEYYNDEEEMKENMGTLTYSPSSSNKSIDDNDTSPSKPTVNKKSAQVKITNRKTVSRTIKDRDVLATNGIRKLYKNLKSSKFSAKHSNKTNLELFFGIYSKWSKEINPAISIEDSIVKIEVLGKSKLVKNHIEDIKHGVYDKDVEDTNNFINMDDDVNSISSSKSPLKNNNNNNSKTNSVNINNNNIGKFNNIVTTTTTKPSYQNPFSFFNNSSSVSSQTINTSFTTTAIKTTTSKTISRPLLKVSLPTRPTIKK
The following text describes a protein:
Function:
Neuropeptides RYamide-1 and RYamide-2 are ligands for the G-protein coupled receptor RYa-R. May suppress feeding behavior.
Subcellular Localization:
Secreted.
Sequence:
MNECVNKLLHLKFLFYFILGIQKRPVFFVASRYGRSTTYDESLKSRRIFIVPRNEHFFLGSRYGKRSGKYLCLSREINKLIVRKRLRNNDKERTPTLSFITKHFLMRNT
The following text describes a protein:
Function:
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Subcellular Localization:
Secreted.
Sequence:
MRLIQALSLCLALSLSLAAPPQHKEDHSHKGKPGGEGHKHELHHGAQLDRCKGIEFDAVAVNEEGVPYFFKGDHLFKGFHGKAELSNKTFPELDDHHHLGHVDAAFRMHSEDSPDHHDHQFFFLDNMVFSYFKHKLEKDYPKLISAVFPGIPDHLDAAVECPKPDCPNDTVIFFKGDEIYHFNMHTKKVDEKEFKSMPNCTGAFRYMGHYYCFHGHQFSKFDPMTGEVHGKYPKEARDYFMRCPHFGSKTTDDHIEREQCSRVHLDAITSDDAGNIYAFRGHHFLSITGDKFHSDTIESEFKELHSEVDSVFSYDGHFYMIKDNDVFVYKVGKPHTHLEGYPKPLKDVLGIEGPVDAAFVCEDHHVVHIIKGQSIYDVDLKATPRKLVKEGTITQFKRIDAAMCGPKGVTVVIGNHFYNYDSVQVMLMAKIMPEQQKVSQQLFGCDH
The following text describes a protein:
Function:
Plays a role in the regulation of phosphate uptake.
Subcellular Localization:
Cytoplasm.
Sequence:
MRKVFDEELLKLHNSILRMGSIVEKQINTCIKALVEKDEKLADEVIKNDDVVDDLEKEIEDECIVLIAKEQPLATDLRKIFTTLKIVTDLERMADHAVDIAKIAKKIKDEKYVKSLIKIPRMADLVQNMIKESLDSYVNENKEGAYKACTLDDEIDHIYKTTFKESIDTMIERKESINQLTQFLFVCKYLERIADHATNICEWTIYLITGEHIDMNE
The following text describes a protein:
Function:
This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
Sequence:
MEAKAVARTIRIAPRKVRLVLDLIRGKNAAEAIAILKLTNKASSPVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSDGKEEAKEA
The following text describes a protein:
Function:
Required for chromosome movement and orientation on spindle poles in mitosis and meiosis. May play a role in early anterior-posterior chromosome movement in mitotic embryos.
Subcellular Localization:
Nucleus, nucleoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome. Note=Localizes to nuclei of the distal mitotic zone. During mitotic prophase in embryos, localizes to the nucleoplasm. In prometaphase, localizes to the body of the spindle and the periphery of chromosomes. In anaphase, localizes to the spindle interzone. Localizes to early meiotic prophase nuclei and to the nucleoplasm in late prophase. Localizes to prophase chromosomes before fertilization. During metaphase of meiosis I and meiosis II, localizes to the body of the spindle, around the periphery of chromosomes, and between homologous chromosomes.
Sequence:
MSSDASLRVVVRARPMNGRETKEGASRCVQFYENTKQIVINESATFTFDAVFADTSDQESVYETTALPLLDRIFAGFNATVLAYGQTGSGKTYTMGTEDNVGTDEMRRGIIPRLVSALFQRIMNTEAPESFAVTVSMFEVYGDNVYDLLRPDKVKLNVHGDEKNCTVVNLTAVPVIDLKGALKQLAVGCHYRTKAETAMNAMSSRSHAVFTVFVEKTATAECDSAFSAKLQLVDLAGSERLKKTEAEGNRMKEGININGGLLILSQVIAALATKQKHIPYRNSVITRVLQDSLGGNSFTVFLACISPADSNSQETLNTLRYADRAKQIKNKPIVNKNPKAEEIAILQAQLKRLQKENADLKQGIAPAEVRFNDANNSAEILSLKEEVVRKTEQLKERAMKQSECIIRMSALTQKNSRLEEDKAKLQSMLTDVRNTVLNEEMLDAAEVVRSIQQVVGDTEESTTLADDDNDETALGGQDDTIYDTERLPELQAELDDLEKQIAMKDENRQKALDEQRAFIEAMQQRESEKTQLVVRISELETEMNKLRQEGKKVTTAAKLAEERRQKLKDLERQHAEDKKVLNDMKKLQETRRRMEETLKKTEDELKNLKTQRLRLLREQRAEASKFQAFKQKHEREMAQMKSKLQKRENDVAIQKRMTDQKLTVLQMRLTEANRANKTLRELNLKRANRKSSPTNASALQNMIEEELEHEMCAQRSHWLCEDLRRQRHDLMQNINTVESMKFEGGKRRRISASADPNVSVVIEGEEEFEVKRQKELTFLRASLETLNEEIKDSLRNETIAGNEERANSRWEKVPAEMRPAFEAVYAQAVAHIRKEIELEFKLARTKSEFTAKIASKASHEEKRKKEDEEMRAKYRELAQCLEDAKSGLHEKIAFLLCLIKENRVDENAIQQFESLKNQFCDVEQKVKKASRRKTTNFMGGLTPKPELQRNERARRAVKYYGNVVNSEDVTMDDSRHQKRKDHSLLAVEMNRTTDDNVKRRVAMSPIKCDDDTRLTEEDEDIENEAMNNATFVKDSFNSATIVLDDSQPSPSNSTFVIGAAPTSEADGVPPIKRKSRRTDLGPL
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MNGLKREHESSSSQDGSKTPETEYDSHVDSIEDIHSLASKRKKLNEKKENLEDLTLLKTSAFELKLNELIREISVRGKYFRHANTFVEKIKDLIFKTPVIPETNFWSACKNLEKDKKVIVPLAEPLSAKDTNLRASFVPPKTVTPGIFSCSNKFFLNPDGWSYDLFLEIPESIFTQKDYLNGRYFRKRAFYLTCIAKHLLENLGNEVKLEFVAFNDDIRRPILAILPESKGFAATGKRFTVFLIPTVRQIFPVSKLLPHKNAIRDFMEHEELKPTPFYNNSVLEEQNLLFYRDLVKKYSVNPQFLDACGLGSTWLNMRGFSSSIHSNGFGLLEWYVLMALLMSSTGLPAGNVLNTYLTAAQFFKSMLQFLSSKNLTSTLFKLNADSSNLKIGNGHLPTLIDCNTGFNLLGKMKQSFFEYFQASCRHTLNLLDENANYNFSKIFITHVNVPALEFDVSGCIPLEPKELEDPNFCRKTDLDSPYSLYLEYTWDLLQHALGDRVCQIILYSSICTSCSINESLKTKLPKLISFGLLLNPDALLRLVDIGPSPDDTVGSQKFREFWGEVSELRKFKNGSIAESVYWECSSPDERIRIPQRIIRHILNRHLGNNVGDRVSFRNEKFRVYVHSKISPNTDTYNEYVPVMEAYNEAVKSLINLSDIPLSIAEILPADESLRYSSSSVPFYESSTCAPIDVVFQFESSSKWPDELEGIQRTKIAFLLKIAELLEALDNVERASVGLENTDNPTHNCCFLQVLFSNNFTFRYRLRNDREIFFWKSLERNPSTKLSAQKGLYAYEHMFQFIPRHTLAIQAICQAHRSYSMAVRLAKHWFYSHLLTDHVTDEVIELLVASVYINSSSWRTTSSGETSFCRMLHFLAHWDWRFDPLIINSNGKLPHDVRHQATEKLESIRKQDVAIAHNAYYIITDYDFDGNHIGYYKPSKIIANRITSLARASLSELLKDTPNYKSIFKSSLDIYHVVIDVNINKLPMYRESNLTKYKNLQNMSSERPGFEPITEFVKELHRCFEDTISFFYNKKNPKVVTGVFNPRILANRPYRTNIDYPFKVVDKDTVVLDADVVCEEIRQVGGDLIRSIQLQLKA
The following text describes a protein:
Function:
Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
Sequence:
MDDVYKAAVENLTEEQKNEFKAAFDIACQGAEDGCISTKELGKVMRMLGQNPTPEEQQEMIDEVDEDGSGTVDFDEFLVMMVRCMKEESKGKSEEELAELFRMFDKNGDGYIDLEELKTMLESTGEAITEDDIEELMKDGDKNNDGKIDYDEFLEFMKGVE
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation.
Subcellular Localization:
Cytoplasm. Mitochondrion matrix.
Sequence:
MLAKTGLLVVSNPTQIGKILPSIQKRVKNTLYIQLLSALSEPFGNFYTNVFTSWPKYSKTLYGIYSQAATHCENLDVRVLLSGLKYQTVSQIQTKSNIDLIIFDRIHSKTDIDNFIKTKVANIASEYNVVTLDSAGDRIEDFICDDDESIYNHTVLGGTFDRLHTAHKLLLTEAALRSRRKVTVGVTEESMLPGKILWELIENLDVRIQNVENFLNDICAELDYNVVPISDPFGPSITDPTMEMIVVSEETVKGSQKINEIRLEKQLNPLDVHSVKLIDEPYPNLNEERKISSSTGRIRLLGTLLRPVAKKNIPNKPYVIGLTGGVASGKSGVANWLIQHEAEIINCDLIGHEVYKSGRPCHTKIVDCFGDSVLTPEGEVDRKVLGSIVFSDSSALKKLNGLVWPAIADEVQKMITNSKNPVVVVEAAVLLTAGWQSFCHEVWSTLVPRSEAIKRLMARNKLTEEQAIARINSQPSNKAYVQEAHVVLCPLWDVEFTGMQVKKAWDLLQDRLL
The following text describes a protein:
Function:
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
Sequence:
MEVVIVPDAKAGGELIAEAMAQLLRRKPDALLGVATGSTPLPVYEALAAKVRSGAVDTAQARIAQLDEYVGLPAEHPESYRSVLRREVLEPLGIDMDAFMGPDGTAADVQAACEAYDTALGGSGGVDLQLLGIGTDGHIGFNEPCSSLASRTRIKTLTEQTRIDNARFFDGDIEQVPHHVITQGIGTILEARHVVLLATGEGKADAVAASVEGPVAAVCPASALQLHPHATVVVDEAAASKLKLADYFRHTYAHKPDWQGI
The following text describes a protein:
Function:
Stabilizes the HMG-CoA reductase HMG2 by preventing its HRD1-dependent degradation. Binds directly to the sterol-sensing domain (SSD)-containing transmembrane region of HMG2, promoting its folding to protect it from degradation.
Miscellaneous:
MISCELLANEOUS: Present with 3390 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MANRGEPDPKKSTESICSLTKPQLYSLYDDDVVRSEDNEIYEELKRSVSIDSTKYSRDQTIDSTFYLAHKVGGSLPRNTVSSNNLERILSASSIHENFPSRTRQTRQNILHYLQAVLILSLSGFAYHELSRNLHDNHLLHPDFASRPLLLGVKLCNWLSNGVLPNWLGYGVEGLLFGSVVPILDNIFQTEVVKSSVHHDSLTSVIRSINAMLGVTFGIRKIQWNSSLQAAGAWGLLNIILWLFFDGSISMLMSCICIGVGCCISCYKDIIDGSQFLYFMDFYFLGSLMFGKLGRYLYSH
The following text describes a protein:
Function:
Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate. Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate.
Sequence:
MLDWVDGRPAAELSVRDRGLAYGDGLFETLAVRAGTPRLLERHLARLEEGCRRLAIPLDTAALRQELLAFCAALGDGVAKLIVTRGEGLRGYAPPAEASPRRILSGSPRPAYPERHWQQGVRLFACRTRLAEQPLLAGLKHLNRLEQVLARAEWSDAGHAEGLMLDVHERVVEGVFSNLLLVLDGTLVAPDLRRCGVAGVMRAELLERAEGIGVPLAIRDVSMAELATADEVFLCNSQFGIWPVRALDEHVWPVGELTRKLQDQLRDDLDF
The following text describes a protein:
Function:
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MEPHLSLHLQRQALSEIRERFSRHRHICVHCSTKNRAAHHGHQHCFIIPYNYPSQKLCGYLSDDGGSDLTFYALLETSCFSKHWLPFCRKFSIEPRSPAAYFSTNPKPHDSNPLMAQDRFSIKKSYEDMKNRIETTTRLGRVSEEIRKEHKGFQEWNHVSTQYNHQSIVQILIDGREDKAVDVEGQSLPTLVYLSREKRPQYHHNFKAGAMNSLIRVSSKISNGSIILNVDCDMYSNNSESVRDALCFFMDEEKGHEIAYVQFPPSYNNLTTNDLYGTCFRVLNEVDLPGLDANGGPCYIETDRTARESASVLEASCKVLASCSYEENTQWGKEMGLKYGCSVEDIITGLSIQCRGWKSISFSPERKGFVGVAPTTLLQSLIQHKRWSEGNFQIFLSRYCPLLYGHKRIPLELQFSYCPYLLWAPNCLPTLYYVAVPSLCLLGGFSLFPEISSLWALPFAYVIIAKYAYSLGEFLWFGGTIQGWWNEQRIWALRRTTSYFFALLDTILKLLGFAETTFAVTAKVSDEDVSRRYEQEVMEFGSPSPMFTIIATLAMLNLFSFVCCVKRVFVGIQIKTLESFALQGILCGVVVLINLPVYQGLFFRKDKGAMPNSVTYKSVALALLACSIALYQ
The following text describes a protein:
Function:
Participates in DNA repair and in chromosomal DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MVGGRIVQGSNLSRQSSFNFGSETKGLPSRPALDSNTSFGMSSLEVEDHEDEDEHLKDPRDWLKVIGAFEQPKMMYNATQKHFDNTHLLLGMLTVSPAGALSLSDLTGTIVLDIQHARPIPETGAYFAPGMIVLVEGSYEEDSGVSSTLGGTGGIGGTIGGKFLGFSVGHPPCERRTATLGGTDEIDKSSLAGPAFGWTDFLGVGSQRATGSRMNKIGSKLLDPEQAHNIVIASDLHLDVPATLTALRTLLRTHTPDPTAAHPVYPLAIILMGNFSSKASLAGVPGAGSIEYKEHFDALASVLADFPQLIAHTTLVFIPGDNDAWPSAFLSGAATPLPRKPVPALFTNRIRRVIAEANREVWGAGKAKGKEGEVIWTSNPSRLSWFGVKGEMAIIRDDLAGRLQRTSIRFPKPDEEVDDEMPFAPSAQDADADADTMDLDLPASHHAPTQQALDHDTLTARSLTRTILSQSHLSPFPLSARPLHWDFAHVLNLYPLPNSLVLADSEAPAFVVKYCGCTVMNPGSLVEGRKGERARWVEFDVRSGSGVVRVEE
The following text describes a protein:
Function:
Protein tyrosine phosphatase that also exhibits lipid phosphatase activity. Can use phosphatidylinositol substrates such as PtdIns(3,4,5)P(3) as substrate. Pollen-specific phosphatase required for pollen development.
Sequence:
MGLKLSRGPVKEKSPLEFTRVHILTYFTTNSYLRNLVSKKRRRLIIGGYDLDMSYISDKLLAMSFPAERMRAVYRNPLWQVKSVLDMRHPDHYKVYNLCIEESYDPDNFYGRVERFPFDDNHVPSLKMIQLFCESVHSWLSLDPKNIAVVHCMAGKGRTGLMVSAYLVYGGMSAEEALEMYASRRTTNNNGVSIPSQRRYVKYWSDLLSFSKKGPPEVKLPQEHSRELLRIRLYDTANVDSVFFVVSELQEVPNEMYRPSVELARGCCRQFKKGYCRSSSPRYYISHVNCDSEEDEEVTDGEEPHLVVQMDTESSIIDEKTCLDFYFDKPVRVSGDIRITFYQKMIGSRLFYTCFNTAFITNGLLQFSIGELDKVGGNGRSISGPDFSLELLFGPACSKFGKFLSRDDLSLS
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
Subcellular Localization:
Nucleus.
Sequence:
MVIPTSADGVRGRKKSSRGHHRFVGVRQRPSGRWVAEIKDSLQKVRLWLGTFDTAEDAARAYDDAARALRGANARTNFELPPSASKTTANRVSLDHIEPFSFEEVCGTGNDADGFLGALKAKLLDGKGLKVLSPANRAALQPIVASNSSQNNQNVSRESRTTTVAPQGIRNMNPVPGPLNPGSSKPDLLNRYQVAANHVGVQWPQPQPGQSQIESMASMMWSNEPSFEAEWGTQMNQVPPNGFFNITTCTAAATSTWPLSGTTESTMDLSYSDQCPIGLQMNMNGKTNMVSMPMSQFDETAEGVWPSPQQFEQCDNNGWSSANGSWDPYLYVSSVLG
The following text describes a protein:
Function:
Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol. Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Endoplasmic reticulum membrane.
Sequence:
MGQTLIRIIGALRPHHFLVTVLCPPSASRSAHFSLITTMSRPAPPASSLEHPANTPAVLLRVFYLAASLLILAIQLVPALRRRFLVYGSRTTPTGKSAPSEEPAQKTALDTLLDDFAAIQVPHNYFTHFYITSVISSLFWGLWLRVWTTPGQLQVVWMLMLLQGVRRLLESDAYTSKSKSRMWFVHWLLGIAFYLAMNVSIWIEGAHQGPRHWSTTMLVPAVLTAHVFQHSFHAYLYRLRSEKKGYQLPSHPIFTNLLCPHYTCEVLIYTFLSFLAAPDGRWVSWTMVCGTIFVASNLGVTAWGTKEWYAEKFGQDKVGHRKRMVPWIW
The following text describes a protein:
Function:
Required for arginine biosynthesis. May participate in the export of matrix-made ornithine into the cytosol (Potential).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MDSVPAQTHQGFKEAGAASASHLTTTTSLPTKVESRTAVMEALEDIVYGSAAGIVGKYIEYPFDTVKVRLQSQPDHLPLRYTGPLDCFRQSIRADGFLGLYRGISAPLVGAALENSSLFFFERIGRSLLYSSGFAPRDSELSLSALWFTGGFSGAFTSLILTPVELVKCKIQVPDEPGGAGARQRQLKPIPVIKEIFRHEGLRGFWHGQLGTLIREAGGCAAWFGSKETTSKWFRGRNERALLKRGASQEEVVASRERPLPLWQQAIAGASAGMSYNFLFFPADTVKSRMQTSPIGGGGDNGGKGAATMMPKKSFGEEARALWKQAGIKGFYRGCGITVLRSAPSSAFIFMVYDGLKKYFPMA
The following text describes a protein:
Function:
Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
Miscellaneous:
MISCELLANEOUS: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.
Subcellular Localization:
Cytoplasm.
Sequence:
MSRTETDSLGTIEVPDDAYWGAQTQRSLENFAIGGQRMPLAVIHALALIKKAAARVNDHLGELPPEVARLIEQAADEVLAGRHDEHFPLVVWQTGSGTQTNMNVNEVIAGRANELAGNPRGGKSPVHPNDHVNRAQSSNDSFPTAMHIAAAKAVHEQLLPAIAELSGGLAEQSARHASLVKTGRTHLMDATPITFGQELSAFVAQLDYAERAIRAALPAVYQLAQGGTAVGTGLNAPKGFADAIAAEIAAESGLPFVAAPNKFAALAGHEPLVILSGALKSLAVALMKIANDLRLLGSGPRAGFAEVKLPANEPGSSIMPGKVNPTQCEALSMLACQVMGNDSTISFAASQGHLQLNVFKPVIVYNLLESIRLLADGCRNFNKHCVAGLEPDAQRMADLLERGLMLVTALNPHIGYDKAAEIAKKAYAEGTTLRAAALQLGYLDEAQFDEWVRPEQMLEAGHHG
The following text describes a protein:
Function:
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis. Has a role in error-correction of aberrent kinetochore-microtubule attachments to ensure that sister kinetochores become bioriented and connect to opposite poles by promoting spindle assembly checkpoint signaling.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and on elongated and disassembling spindles. Also associated with the kinetochore (By similarity).
Sequence:
MMLPRNSPHRTESTLAYNNNNSNNNNNNNGSSLFQRKPLAPINSEFKISKPQHIKPTTHSHTFTTPTPKTRNTATTTTNNNNRNNHQYRNPNLNTSLVFTPTKNSSSSSSSHSSSLLSSSPFVEEPENQPESNHTRATSHYRTTSTSQYKSSANKDASHSLITSSKRKTSTKQTSESTNPKRRTTTTATQNTNNNKILNPSLSSSTIRFSTVSSSTSSSTTSSSSSSHTSPKPQQQLTLDDFEFGKILGKGKLGRVYCVKHKQSGLIFALKVMSKSEIMNLKLEKSLRREIEIQSNLYHINITRLYSWFHDSINIYLLLEYSIEGELYTHLKKLKRFDNIMASNYIFQITQALIFLHQRGIIHRDLKPENIMVSLDNQLKLSDFGWSVQINQNQNQNQIHNQTQTQKTPHQKKQKQKRLTICGTLDYLPPEMIESKSHDFSVDIWALGILCYELLVGKPPFEAINRNITYEKIAKVDIKYPSNLDVDAIDLISKLVVKDPNKRLSLKEVLNHNWIIKNKPKWPKNIYK
The following text describes a protein:
Function:
Antimicrobial peptide.
Subcellular Localization:
Secreted.
Sequence:
GIMDTLKNLAKTAGKGALQSLLKMASCKLSGQC