lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (Probable). Increases the presence of activated RAC1 at the leading edge of migrating cells. Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments. Plays a role in endoplasmic reticulum-associated endosome fission: endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane. Required for normal cell proliferation, cell migration, and normal formation of lamellipodia. Required for normal distribution of mitochondria within cells (By similarity).
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cell projection, ruffle membrane. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Endosome membrane. Note=Colocalizes with the actin cytoskeleton in the cytosol, and especially in the cell cortex (By similarity). Colocalizes with F-actin at the leading edge of lamellipodia (By similarity). Partially colocalizes with microtubules and vimentin intermediate filaments (By similarity). Localizes to endosome membrane tubules/buds (By similarity).
Sequence:
MFKRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSAFCAVNPKFVALIVEASGGGAFMVLPLHKTGRIDKAYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLVTSMSEPVVVLEGHSKRVGVVTWHPTARNVLLSAGCDNMIIIWNVGTGESMITLEDHHPDIIYSICWNRNGSLICTACKDKKIRVIDPRKEEIIAEKDKAHEGARPMRAIFLSDGKVFTTGFSRMSERQLALWDPENIDEPVAVHEMDTSNGVLLPFYDPDTNVVYLCGKGDSSIRYFEITDEAPFVHYLNTFTTKEPQRGMGYMPKRGLDVNKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPDAPLEAEEWFEGKNGDPVLISLKHGYIPGKNRDLKVVKKNILDNKMSKNTENTTPAHKTATSTPSIKSEAKLEEVLKEIKSLRELVSSQEKRIGKLEEQLSKMDI
The following text describes a protein:
Function:
Has double-strand break activity.
Subcellular Localization:
Periplasm.
Sequence:
MYRYLSIAAVVLSAAFSGPALAEGINSFSQAKAAAVKVHADAPGTFYCGCKINWQGKKGVVDLQSCGYQVRKNENRASRVEWEHVVPAWQFGHQRQCWQDGGRKNCAKDPVYRKMESDMHNLQPSVGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKEKAAEPPARARGAIARTYFYMRDQYNLTLSRQQTQLFNAWNKMYPVTDWECERDERIAKVQGNHNPYVQRACQARKS
The following text describes a protein:
Function:
Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In follicle cells, the complex plays a central role in the site-specific DNA replication at the chorion loci. During development, the complex represses transcription of developmentally controlled E2F target genes.
Subcellular Localization:
Nucleus.
Sequence:
MDTSGGNLDSLDDTEPLPELSFEDFLEPTSEKSSQHMEIEALDSEEDNIGGEDLADPANDSLNTPQFKKNVVHILEDKRLNSSGLTVLKSHAIKMVTAGGTPPAKAQVTDVKILNKLKPIPSSTLKIGSTTIATKSTPGSITKTLGNLTQIRTKDGQVIFVQKSVPGTQSSTAVTGSPSGGIRRLVAPSGIQKAVLSKGVTMASTGLVKAAVPAKASTSVPGSAITLKGIQPLAGGTAKASTSSTTATTSPSLAQPNKIQVVRTADGKIIKINQAGPSLLVNAKQGTGTTVTPGGSAATSVKLSPSTGNVVLNKPVGQVVVRTETPVKTATGSVASASATPGKMLVQSGGKQILVSNKNIIKLSPNASATSSTTHTTGGQTPSTSSGLHAIQLPGKGGIQYVRVLNNNKSAAGTSATASIPKTVQTQKITVVRPPAATGVPATSTTTSAAAASPAAASKANLAMGNTNKIVMRSMGGSIVPLPSVQTLVSKRALGAISNASKPASAASSSATPSASQELPRKHRLTDLNVQLKQSASVSSEASDSSDAGPEAKKPRYVITMQQGSQKAASQPVQKLINRTANVQRVVSSSTSPSSNSTKKIYNYVQPTGSNGAKYMICNSGVPQSSTSAMRRGYTGYVENKTRRPPPISPQQHRFKQMGPQQQSKHQQLQAQAKQRIRQQQLPTEQSTPIKVEPKLPTLPPGVKANVPAKPLFEVLKPPATAAAAGAVDPLGGMTSRRKHCNCSKSQCLKLYCDCFANGEFCQDCTCKDCFNNLDYEVERERAIRSCLDRNPSAFKPKITAPNSGDMRLHNKGCNCKRSGCLKNYCECYEAKIPCSSICKCVGCRNMEDRPDVDMDSLDGLMGVEGQKKDKAKNKQLNENRANIYFTDDVIEATIMCMISRIVMHEKQNVAVEDMEREVMEEMGESLTQIIAFAKEKQETSQIDESKPSS
The following text describes a protein:
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Nicotinic acetylcholine receptor in the MC pharyngeal motor neuron involved in pharyngeal pumping. Has a role in the determination of life span possibly via calorific restriction which affects growth rate, although this is independent of metabolic activity (By similarity).
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=MC motor neuron.
Sequence:
MFLLLQILYILLFLNLADTSDDEYRLLKDLREGYDPMERPVSDHMKPVNVKLRLILQQLVDVDEKNQVITLVVWTQYTWNDYKMKWSPEEYGNITSLQIPFGTLWKPDILLFNSANEHFDSSFPVNMVVSNDGNVLFAPPGIMQFSCSLSMTWFPYDEQVCYLKFGSWTYGKKLDLRIDDADLPEGHKMDLQYYVPNGEFDLISTPAFRKSTTFLDETYVELYFHMHLKRRTMYYGLNWIIPSILISLSNILGFTMPVECGEKVTLQITNFLSIMVFLAMVSEVAPPTSESIPIIAAFFSFAIVILGVSICVSLITVNIFYRHPKMHRMGDWTRYIFLEWLPWFLLMSRPDHVFRKPKREKKKEEEEDEESNAGGKEEESELISQKQQRPRLLVNSQIVMDSTIPYLEEVIGYLKVFKAKLDDDEEEEEEILNWRFMAMVIDRASLFLFTGLIFGTTFVIFAACPNLFSADQIIETEPVIT
The following text describes a protein:
Function:
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
Sequence:
MPRKAQAAGTGAPEPTGARAPETSLASPELYLNRELTWLEFNRRVLHEAEDTRTPLLERVKFTAIVSSNLDEFFMKRIGGLKQQVGAGLQHPTVDGRTPRQQIAECYAVVRDLAERKRRVFGELLGLLRDGGIRILGYSELSEKERKGLRQHYQRNIYPLVTPQSIDPAHPFPFISNLSLNLLVTLRYPRERETSLARVKVPVGAGIPRFIRVGDDDRFVPLEEVMRHNLDMLFPEMEVTACELFRVTRNANTERNEEQADDLLSLIESELQDRRFAPIVRLEVGADMDPVHRGMLAAELELTEADDVFDVEGMLAFRDLFEIAALGYPELRDPPHHPVDHPRLMTDRNIFHVLRDAGAILLQHPYDSFATSVERFLMEASEDPKVRAIKMTLYRTASDSRIIDCLVNAANNGKQVAVAVELKARFDEAANIRLAERMEEAGIHVTYGVVGLKTHCKVILVVRQDYNGLRRYVHIGTGNYHPGTARVYSDLGLLTSDETIGQDATELFNYLTTGYTPRRNYRKLLPAPKHLKRALLARIEREAELHSEKSPGLIQFKMNALEDADIVAALYRAARQGVRIDLIIRDSCRLRPGVPGLSESVRVVSVVGRFLEHARIYYFRNGGDEEYFIGSADAMKRNLEYRVEVLAPVEAPELRKELRTMIDVQLGDRRSAWDMRPDGSYVQRMPGEGDDPRGSHEILVDLAEKRRKAGARLKKKKARGVVRRPVR
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MAASLPIFHLLPNHHPAYPPSPTFSDPAFSAQYDSAFPANMDLSKSSQHPLNGYPFPAPPGTSAPQYSSRHIPSYPNLVPPNFSRGSYPAVQGGEDPTTFLDLDLSQPGPSTYHQQQPQPQSAAHHYHQPDHEYVQSDAEDDESLVQVKEEQDERQEGEEQDADVDNEEPLYVNAKQYHRILKRRMARARLEELNRLVRSRKPYLHESRHRHACSRPRGKGGRFLTAEEIETLKRQEAEKASKGEDEAQASA
The following text describes a protein:
Function:
Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introduction of positive charges in the otherwise neutral PIA polymer, allowing electrostatic interactions (By similarity).
Subcellular Localization:
Secreted, cell wall. Note=Attached to the cell surface.
Sequence:
MKYRKFIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENSALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLDMISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPVIKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD
The following text describes a protein:
Function:
Induces host (human and mouse) cytokine release by monocyte cell lines via TLR2 and CD14; nonlipidated protein does not stimulate host cells.
Subcellular Localization:
Cell outer membrane; Lipid-anchor. Cell surface.
Sequence:
MKKYLLGIGLILALIACKQNVSSLDEKNSVSVDLPGEMKVLVSKEKNKDGKYDLIATVDKLELKGTSDKNNGSGVLEGVKADKSKVKLTISDDLGQTTLEVFKEDGKTLVSKKVTSKDKSSTEEKFNEKGEVSEKIITRADGTRLEYTGIKSDGSGKAKEVLKGYVLEGTLTAEKTTLVVKEGTVTLSKNISKSGEVSVELNDTDSSAATKKTAAWNSGTSTLTITVNSKKTKDLVFTKENTITVQQYDSNGTKLEGSAVEITKLDEIKNALK
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MATVEVLVQNLSSRGAQARNVLQSVPPQRRAQLLLQNMAGLSNRLLEVAGNKDWQTGQNKLMAPTLLQGAVLPPEGAAATTIKDVLGLLDYHQTLLFEAIAELAELQEMENEKQRIVDAIATKDLAMRDFAKRVRDAQQVLEATVEEFDDYRRPKRKGVTDECSGIGLGTINVQELVAYAHRISYTTFAPPEFAEGAALRGALPPAPQDEQMRASKLYHVSELDLGLPKVFERVVSPLMGADADTKVEGGFTPHAGPGGLPPPPPGWKPGMPLELPLELPPMPPGWKPGDPIPLPADMPPLPPAGWKPGDAVVLPPAFAPFPGVEGAAPAGPIKAPPLPAPPIPASGVIHVPFVQLDLNPELEDEFGSEYSDDDGSSDDDD
The following text describes a protein:
Function:
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Plays a role in the recruitment of PRDX3 to early endosomes.
Subcellular Localization:
Cytoplasm. Early endosome. Membrane.
Sequence:
MLSPRERGGELARFYTVTEPRRHPRGHTVYKVTARCSGSVADITALQLHWLSWCSAALGDRQERSGIVSRKNPEDVQEIVVWKRYSDFKKLHKDLWQIHKNLCRHTELFPPFAKAIVFGRFDETVIEERRQCAEDLLQFSANIPALYNSKQLEEFFKGGEVHDGSELIGPVEPLSDSLTDNLSDCSSEVRKDLSGLDDVTLTSQSECGGFSSDSDLISLTVDVDSLAELDDGMASNHSSPSRAVGLCLTSEPPIQSTVASEQEWSKPEGERESHGLFSGSLKPKPGKQDYLEKAGELIKLALKKEEEEDYETAFSFYRKGVDLLLEGVQGESSPTRREAVKRKTAEYLMRAEKISTLYHKSSEDASVSMPPGSLSSRPSWNLRSPAEELKAFRVLGVIDKVLLVMDTRTQQTFILKGLRKSSEYSRSRTTIIPRCVPNMVCLHKYIISEESVFLVLQHAEGGKLWSYVSKFLNTSPEQSFEIPEPKTFSSTKIHLERPTPSPKEISSSTDSRESYGENMLKVVPLRSSLTPSSQDDSSNQEDGQESSKWMDSASSSEEECTTSYLTLCNEYGQEKIDSGSLNEEPVVKGESQSLNIKEKSSLQKHAVVSSASFSSQVPSQELKLFIDDAESEIASPTRILDSLTKSKNSPMELFRIDSKDSTSELLGLDLGEKLYNLKSEPLKPLFSVPGHDRSLDALESKMGVRAQDTVSRGSNDSVPVISFKDAAFDDVSSVDEGRPDLLINLPSMSDGTEEAAASRPAKTDMDVLEVKLLETPDVLQLNSSAEQCKAFNQEPNHVTPQVGDPSPREVNGQSGVTQGALGTLFTSDPEVGSSEDGALFQGPGACSINMTSKEESVFVSNLLSGAQDVSLDRDTLRNEAVLLFSDQTEDFGKEETNLSLLPAAESEQTAPKREDKIAVAGEKDIHQIFQDLDERLAITSRFYIPEDCIQRWAAEMVVALDALHREGIVCRDLNPNNILLNDRGHIQLTYFSRWREVEDSCDNDAIERMYCAPEVGAILEETEACDWWSLGAILFELLTGKTLVECHPSGINTHTSLSIPDHVSKEARSLIQQLLQFNPAERLGAGVAGVEDIKSHPFFALIEWADLVK
The following text describes a protein:
Function:
Transcriptional activator that binds to the RPG box and to telomeres. Involved in the regulation of the transition between yeast and filamentous forms and plays a role in virulence. Induces expression of HWP1, a major hyphal cell protein and virulence factor.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MSSNKNQSDLNIPTNSASLKQKQRQQLGIKSEIGASTSDVYDPQVASYLSAGDSPSQFANTALHHSNSVSYSASAAAAAAELQHRAELQRRQQQLQQQELQHQQEQLQQYRQAQAQAQAQAQAQAQAQREHQQLQHAYQQQQQLHQLGQLSQQLAQPHLSQHEHVRDALTTDEFDTNEDLRSRYIENEIVKTFNSKAELVHFVKNELGPEERCKIVINSSKPKAVYFQCERSGSFRTTVKDATKRQRIAYTKRNKCAYRLVANLYPNEKDQKRKNKPDEPGHNEENSRISEMWVLRMINPQHNHAPDPINKKKRQKTSRTLVEKPINKPHHHHLLQQEQQQQQQQQQQQQQQQQQQQQQQHNANSQAQQQAAQLQQQMQQQLQASGLPTTPNYSELLGQLGQLSQQQSQQQQLHHIPQQRQRTQSQQSQQQPQQTPHGLDQPDAAVIAAIEASAAAAVASQGSPNVTAAAVAALQHTQGNEHDAQQQQDRGGNNGGAIDSNVDPSLDPNVDPNVQAHDHSHGLRNSYGKRSGFL
The following text describes a protein:
Function:
Involved in pectinase, cellulase, and blue pigment regulation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKLKDFAFYAPCVWGTTYFVTTQFLPADKPLLAALIRALPAGIILILGKNLPPVGWLWRLFVLGALNIGVFFVMLFFAAYRLPGGVVALVGSLQPLIVILLSFLLLTQPVLKKQMVAAVAGGIGIVLLISLPKAPLNPAGLVASALATMSMASGLVLTKKWGRPAGMTMLTFTGWQLFCGGLVILPVQMLTEPLPDLVTLTNLAGYLYLAIPGSLLAYFMWFSGLEANSPVIMSLLGFLSPLVALLLGFLFLQQGLSGAQLVGVVFIFSALIIVQDISLFSRRKKVKPLEQSDCVIK
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. Counteracts the effect of cognate toxin RelE via direct protein-protein interaction, preventing RelE from entering the ribosome A site and thus inhibiting its endoribonuclease activity. An autorepressor of relBE operon transcription. 2 RelB dimers bind to 2 operator sequences; DNA-binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity. Increased transcription rate of relBE and activation of relE is consistent with a lower level of RelB in starved cells due to degradation of RelB by protease Lon; Seems to be a principal mediator of cell death in liquid media.
Miscellaneous:
MISCELLANEOUS: A number of site directed mutants give rise to a delayed relaxed phenotype; RNA synthesis resumes 10 minutes after amino acid starvation, an unusually slow recovery from periods of starvation, accumulation of a translation inhibitor; MISCELLANEOUS: There are estimated to be 550-1100 RelB and 50-100 RelE molecules in rapidly growing cells of MG1655; as they have quite high affinity for each other (dissociation constant of 0.33 nM) there is probably less than 1 free RelE molecule per cell. The RelB(2)-RelE complex has a half-life of over 70 minutes.
Domain:
Dimerizes and binds DNA via its N-terminus (residues 1-50), binds toxin RelE via the C-terminus (residues 47-79). Tetramerization probably requires amino acids between residues 66 and 71.
Sequence:
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDEL
The following text describes a protein:
Function:
Transcription factor that acts as a positive regulator of leaf senescence. Is involved in both the onset and progression of leaf senescence. Upregulates the expression of genes controlling chlorophyll degradation and leaf senescence. Acts as a positive regulator of the senescence-associated NAC genes NAC4 and NAC58. Acts as a positive regulator of abscisic acid (ABA) biosynthesis during leaf senescence. Acts as a negative regulator of drought tolerance by inhibiting ABA-induced stomatal closure during drought stress. Functions as a direct negative regulator of MYB2 transcription through binding to the repeated W-boxes of the MYB2 promoter region.
Miscellaneous:
MISCELLANEOUS: The gain-of-function mutant plants oswrky5-D (T-DNA activation tagging) promote leaf senescence under natural and dark-induced senescence conditions. Overexpression of WRKY5 reduces grain yield under normal and drought stress conditions.
Subcellular Localization:
Nucleus.
Sequence:
MEMMVQKQRHEEGEEERGGLCAREIKELDFFSAAGAGAGRRDDDDVLRADGISSSHAGFMVSTALDLLTAVNDGDHHEEKKGQSNIHQSKQMDAAATTVEGELRQAGEENRRLRRRLEELTSSYGALYHQLVQAQQLHTKHQQQAPIAGVQLLDALAAASPASHRRRAAAAVDGDRTADSDGGEGDENVSPSLGSKRPAAAATLTRLTPESGSGGENNGGGEQAPAAEMAPCRKARVSVRARSEAPMISDGCQWRKYGQKMAKGNPCPRAYYRCTMASQCPVRKQVQRCAEDKSILITTYEGTHSHPLPPAAAAMAKTTSAAAAMLLSGPAVSRDALFAAHHHVVAPPPFFHHPYAGSTMATLSASAPFPTITLDLTQPPPTTTTTAAAAMLQLHRPYAFSSLPFSMYGAGGGSHRPPVVLPPPSSVVETMTAAITRDPNFTTAVAAALSSIMAGGGAQARTPPRGGSDAAGDINGGGGADHATAGARAAAAATQPCGTSPT
The following text describes a protein:
Function:
Component of several Gcn5-containing histone acetyltransferase complexes that regulate nucleosome organization; involved in acetylation of histone H3, particularly on Lys-10 (H3K9ac) and Lys-15 (H3K14ac). Regulates the transcription of a subset of genes during development; affects recruitment of RNA polymerase II. May be involved in the function of some acidic activation domains, which activate transcription at distant sites. Involved in the p53-dependent apoptosis pathway response to DNA damage by genotoxic agents; [Isoform B]: Component of the SAGA histone acetyltransferase complex, which predominantly acetylates histone H3; [Isoform A]: Component of the CHAT histone acetyltransferase complex, which predominantly acetylates histone H3.
Subcellular Localization:
Nucleus. Note=Almost completely colocalizes with Ada3 to euchromatic interband regions of polytene chromosomes; [Isoform B]: Nucleus; [Isoform A]: Nucleus.
Sequence:
MTTIADLFTKYNCTNCQDDIQGIRVHCAECENFDLCLQCFAAGAEIGAHQNNHSYQFMDTGTSILSVFRGKGAWTAREEIRLLDAIEQYGFGNWEDISKHIETKSAEDAKEEYVNKFVNGTIGRATWTPAQSQRPRLIDHTGDDDAGPLGTNALSTLPPLEINSDEAMQLGYMPNRDSFEREYDPTAEQLISNISLSSEDTEVDVMLKLAHVDIYTRRLRERARRKRMVRDYQLVSNFFRNRNYAQQQGLTKEQREFRDRFRVYAQFYTCNEYERLLGSLEREKELRIRQSELYRYRYNGLTKIAECTHFEQHAATATHRSTGPYGHGKTDHTHTSNGSHRPPSSSLHSPQPNLRKVEMSSGGEASSNSIAPRNTLHIADPTCSGALLPSKNYLDSCRGSSAATMLQTTGMVMGVTVDSGATTGVTSTATTMANLPTNSAKGSQQHLQPLQQHPQLLQSGNQHKMQNEAAGGGSDQVPSMSLKLRTQLEELKHLPQPPGSELLSHNELDLCKKHNITPTTYLSVKTVCLSGAPSLGSPMETSLRKFFIKCGWLSH
The following text describes a protein:
Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Also a component of the nuclear pore complex; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
Subcellular Localization:
Cytoplasm, cytoskeleton. Nucleus, nuclear pore complex.
Sequence:
MSDKAPIPEKKAVIKSVDMADDMQRIIIDLTMQALDKYSIEKDIAAYVKKELDQRFGVTWHCIVGRSFGSYVTHETKHFIYFYVGQIAILVFKTS
The following text describes a protein:
Function:
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MKSVIIASLACSAAAFAPAQVGRSSTAVQGFENEPGVIAPTGFFDPLGFTDDIDQEKFDQYRTAELKHGRVAQLAVIGYIVPEIFRWGFDIAPGVACADVPNGVAAIDAIPALGWAQIIFAIGAVDVRGWFGNFDIGKPDLKGKDEERALQELQHGRLAMLAILELLRHDSQNLVKPGFDGLDNLITGLPFLYN
The following text describes a protein:
Function:
Catalyzes the cleavage of 2-ketobutyrate to propionyl-CoA and formate. It can also use pyruvate as substrate.
Subcellular Localization:
Cytoplasm.
Sequence:
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
The following text describes a protein:
Function:
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Sequence:
MSDMEETVVRIGTRKSQLAMIQTHSVVDALREIHPKARIEIVTMDTIGDRVLDKALPEIGQTNLFTKDLEVALTDNKIDLIIHSLKDVPSTLPEGLAIAAIGNVIGTSSLRRIAQLKRRFPHLKFENVRGNLNTRLKKLDESGIYDALVLAGAGVELTPDECLYAIGQGALGIEIRKNDKKTFSLISAYTDFDSLVCNAAERAFLRFLDKGCSVPIGVYTEFTENKLKITGAVFSLDGSKRVQYSDECTISGLNAKDDCESNYESLSSILCPSEMCNSLIEAERLGKYVAEMILKNHGGEVLAEARQIMKAHQK
The following text describes a protein:
Function:
Carboxylesterase acting on esters with varying acyl chain length.
Sequence:
MGGTKLTHVTTTNPNNSNIHGPVVDEVEGLIKVYKDGHVERSQLLPCVDPSLPLELGVTCSDVVIDKLTNVWARLYVPMTTTKSSVSKLPLIVYFHGGGFCVGSASWLCYHEFLARLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAILWLNKARNDNLWAKQCDFGRIFLAGDSAGGNIAQQVAARLASPEDLALKIEGTILIQPFYSGEERTESERRVGNDKTAVLTLASSDAWWRMSLPRGANREHPYCKPVKMIIKSSTVTRTLVCVAEMDLLMDSNMEMCDGNEDVIKRVLHKGVGHAFHILGKSQLAHTTTLEMLCQIDAFIHHYDPLN
The following text describes a protein:
Function:
Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins. Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAVKLHSVGVPLEESVLHCQAKTSCYVDSDIISSGTLYVTSSNVLWMNDEQKGFAVNYDSISVHAISKAINYFPHPCIYMMVSELSCEYDKARNKNCNLEANGHDVEKDDEDEEDDDHEDRIIDLRFVPSDVNSLNAIYEAINKGSCLNPCAEDADLSEDDNFEPVEEMGQGDGVENANGNDDVEDENGEGDPDQFANADEEEGGAADVDESAMEG
The following text describes a protein:
Function:
B.japonicum has two FixLJ-dependent FixK homologs that are activators of the transcription of a group of genes involved in anaerobic processes such as denitrification and possibly nitrogen fixation. FixK may bind DNA at the FNR consensus binding site.
Miscellaneous:
MISCELLANEOUS: Possesses 4 cysteines which may bind a metal ion (possibly iron).
Sequence:
MKPSVVMIEPNGHFCSDCAIRTSAVCSSLDAAELREFEHLGRRVHFSSGETVFSEEDITTSFYNVLEGVMRLYKLLPDGRRQIVGFALPGDFLGMNLSGRHNFSADAIGAVTVCQFAKAPFGRFIEERPQLLRRINELAIRELSQARDHMVLLGRRSADEKVAAFLLGWRERLLALKGASDTVPLPMSRQDIADYLGLTIETVSRTFTKLERHGAIAIIHGGISLLDPARVEALAAA
The following text describes a protein:
Function:
Secreted immune-induced peptide induced by Toll signaling. Has a role in resistance to bacterial and fungal infections. The strength of antimicrobial activity appears to correlate with the overall level of expression.
Subcellular Localization:
Secreted.
Sequence:
MKWMSLVFLCGLLAMAVASPLNPGNVIINGDCRHCNVRGG
The following text describes a protein:
Function:
Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. Required for TCR-induced apoptosis and expression of TNFRSF6/FAS in a T-cell hybridoma cell line. May be involved in translational regulation.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle. Nucleus, nucleolus. Note=Colocalizes with intracellular vesicles.
Sequence:
MRRTPAAERLSELGFPPRRGRQEPPFPLGVTRGWGGWPIEKRREGPRPVPFSERSPEDGREQPAHGSGILWRVRTRLSLCRDPEPPPPPPPLCLLRVSLLCALRAGGRGSRWGEDGAGLLLLPPAGASGSLKAERSSSTPYAGRMLENSGCKALKEGVLEKRSDGLLQLWKKKCCILTEEGLLLIPPKQLQQQQQQQQPGQGTAEPSQPSGPTVASLEPPVKLKELHFSNMKTVDCVERKGKYMYFTVVMTEGKEIDFRCPQDQGWNAEITLQMVQYKNRQAILAVKSTRQKQQHLVQQQPPQTQQIQPQPQPQIQPQPQPQIQPQPQPQPQPQPQPQPQPQPQQLHSYPHPHPHPYSHPHQHPHPHPHPHPHPHPHPYQLQHAHQPLHSQPQGHRLLRSTSNSA
The following text describes a protein:
Function:
Possesses 5'->3' exoribonuclease activity. Acts as an endogenous post-transcriptional gene silencing (PTGS) suppressor.
Sequence:
MGVPSFYRWLANKYPKTVVNAVEKTEEKDGTRPNPNDLEFDNLYLDMNGIIHPCFHPEHDDVLSKYLTTPGTYEEVFSNIFEYIDRIMMIVRPKKLLYLAIDGVAPRAKMNQQRTRRFRNAKDQETLRKEEDRLRRQYEVEGKDVLPKQDSEVTDSNIITPGTTFMFELSKQLQTYVHLRVSKNDAWKHLKVILSDANAHGEGEHKIMSFIRLQRTCPGYNPNTHHVLYGLDADLIMLALATHELHFSILRENVLAEDKSKTSHSSVLLQAGNSETNVVKCRGWFKQFDLNSDKVDISQQMNKLDITAAGKQKLLVKKPHQFLHVWILREYLNFDLRSTNVPENFEYDIERLIDDFIFICFFGGNDFLPHMPTLEIHEGGIDLLIHVYKQEFKNLGGYLVNMEKVYDKKGGYIKVKRVEKFILALGTYEDQIFKKRSAIHESKLRRMFSEFKDESGNGEEELFPVISTHNQKGPYTEKSPDHDVQIIENTKALKEQLKSYNREISDVFRNGLLSDMVWKIFVVKLDTPGWRKRYYKYKFSAETDADVEKMRKEVVERYTEGLCWVLLYYFSGVVSWTWFYPFHYGPFASDFKGLSSTKVTFQRGSPFKPFDQLMSVLPPTSAHALPPPYRLLMTTDDSNILDFYPNDFDVDTDGKRFLWQGICKLPFIDEKRLLASTKMIEKELTVRMAEWYLEIRTFTCLTRTLINIVFYIQEEEAQRNAENADKLFLHSEENLALQIISSFNNEGSIEQKSSMKVDTGLSGDINGFVYPNLEPKYVCDVNDLGSDHDVLCVFYDPPCFSHHIPRVLEGTDIPDSDVSEADIKEVRLWHESHGYPVRSNRCHGQPEEDKIDPSVGLASGWRGRVNEIASSSQSRIQERHFRHGTHSYPNRSNRSYEQVQGAQRSPTIRAVGGWSGRGRGRGHDATLNSQSTSRHDATRTPKEQTNCSSWWDTHGRGARRNGNCENRSINYNGRTSTVNGQFWAVRSESSSSNQGRGQWGDAKSKNASNRRW