lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Pathway-specific regulatory gene of nitrate assimilation; it activates the transcription of the genes for nitrate and nitrite reductases (niaD and niiA).
Subcellular Localization:
Nucleus.
Sequence:
MGEKLDPELSSDGPHTKSSSKGQGTSTDNAPASKRRCVSTACIACRRRKSKCDGNLPSCAACSSVYHTTCVYDPNSDHRRKGVYKKDTDTLRTKNSTLLTLIQALLNYEEEDAFDLVRQIRSCDNLEDVAQSLVNQEKKSSGWLSNAVIHEENDIAQTDQFESELAGKMSNLVLDGSRKFIGGTSNLIFLPPGSELNEFKPGLATNGDLEGSVTRWTTVTDDQQLISHLLTMYFSWHYPFFTTLSKELFYRDYSRGVPSQYCSSLLVNTMLALGCHFSSWPGAREDPDNSATAGDHFFKEAKRLILDNDELVNSKLCTVQALALMSVREAGCGREGKGWVYSGMSFRMAFDLGLNLESSSLRDLSEEEIDARRITFWGCFLFDKCWSNYLGRQPQFTTANTSVSAVDILPNEESTLWSPYSDMGPSREYAQPSRTRAVADQISQLCKISGDLVVFFYDLAPKEKPSSKQLELKKLSEIHTRLEAWKKGLPKELEPREGQLPQALLMHMFYQLLLIHLYRPFLKYTKSTSPLPQHVSPRKLCTQAAAAISKLLRLYKRTYGFKQICNIAVYIAHTALTIHLLNLPEKNAQRDVIHGLRHLEEMGESWLCARRTLRILDISASKWQVQLPREAVIVFEQTHARWGSWGPWDQAASPSTTSDSPPSVSSQSVVATTDLSQPVSQSAGNQPANPSMGTSPNLTQPVASQYSSTPSGPVSVSAMRAVQRSFSAQLAHNEARQPEPTYLRPVSTSYGPVPSTQSAQEQWYSPTEAQFRAFTAAHSMPTTSAQSPLTTFDTPENLVEESQDWWSRDVNALQLGAEDWTQNWNNGLPTTSADWRYVDNVPNIPSTSAPDADYKPPQPPPNMARPNQYPTDPVANVNSNQTNMIFPGSFQR
The following text describes a protein:
Function:
Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules. Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle.
Subcellular Localization:
Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Nucleus.
Sequence:
MAAHKRSTSAVPGTREMSYFEQQRQALIEEIAMNFEHVLANINKLNRSLEAVIAVGNEFSSVEALWSQFENVMAKAPEEEANAKAGEEQEGDGNAGAGDRGANDAGQV
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSSSLAEKSTFSRTCTLLRQYLKEKGSFGDLTLGIALPCTNGSPDTSCHSATTMQSVYPRHLEIPTFINPSSTEKEAKAAQLTIFYDGQVVVFDDFPADKVQEMMSLALATKGISQSQNSSAYAQTHNQQGNNHPSSIPNIIPQAPSTPIVNDMPIARKASLHRFLEKRKDRIAAKSPYQTNSPISAPNKQAESLDAKPHI
The following text describes a protein:
Function:
Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
Subcellular Localization:
Nucleus.
Domain:
The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.
Sequence:
MEISKITSPEDWEYFAKGAANILFKYTGNNDYLKRKLLRLRLLKQEEEYISTCELYDFIELRCKDLFPNQIIDIQLTVLDSNFTNKLNSQGNKLMLNERYGLLLPNILDGDYRKISLSQKCQLYFNDNDQDINSVIFEIKPKWLYDNYTDNYCRTCSLNQLKKVPRHFCPLDLLYTETIEQGLNDLFAPIPQDIYAKIEKLIPLKKLTTIYFNNPDNVFQKLKQYQKINNKNDLIKNLTSYSDVSQNLSLVMTLRDVGLFIKIEKFDKNNHIHTSHNNIKNVYRINDNKSNGTKDQDQEIGTNDEEDNDEKFLITCNIYDLDLKSKMKYKHWLKVENDLQEIYNSSNPNWRYCIKYDQIHH
The following text describes a protein:
Function:
Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
Sequence:
MSWRVSCKTALLDELFTYIAGKTDANTLQKECVLALPQLETLAKMLGFSLDDMSMYRLAWSWSCEAPLCIRKSEFVNGMNAICSGVKLSATATSSTCSASPVKSPKKEFEPILLALRNHVETLDGALRGDVTKFRHFYRFIYKWVQSPLTMERNMGQVGMSIETAVELWRMLFPHYREFKRLDDWITFCMSKKLFPHGIISRDLWEQLLEFTFVTDYSKYDVSDAWPSAMDDFVEYVKSKV
The following text describes a protein:
Function:
Required for spermatogenesis. Could be required to process a specific transcript essential for spermatogenesis.
Sequence:
MVKDEPLSDESADVIVLADREEDDICELEHLRKLFIGGLAPYTTEENLKLFYGQWGKVVDVVVMRDAATKRSRGFGFITYTKSLMVDRAQENRPHIIDGKTVEAKRALPRPERESRETNISVKKLFVGGLKDNHDEECLREYFLQFGNVVSVKLLTDKTTGKRRGFAFVEFDDYDAVDKAILKKQHAIKYVHVDVKKSIYNLDKKEKQQPGGLANAIKPSLNQQQQQQGGGQQPPNGNMQAPSFRPPVPPQQAMGPYQQQPPPAPMSAPPPNFNYWGPPPPAMPPYYQQPPPQQMNGWGPYPPPQQNGWNAPPPPPPGAQQWHANQWGCPPPVQQVPPVGAVPPPMGHNGPPPTAPGNWNMPPPVPGAAPPSHQQQSSQQPTPQPNFGTGYQQNYGGGPSKHNNMNANRMNPYSAGPPNSYHTPQPPAYTGYNAGPLPPNGSVPPPTGAKAVGVSNGSVATGGSANSKYRR
The following text describes a protein:
Function:
Involved in the insertion of nickel into the carbon monoxide dehydrogenase (CODH).
Sequence:
MKIAVTGKGGVGKSTIVGMLARALSDEGWRVMAIDADPDANLASAIGVPAERLSALLPISKMTGLARERTGASETTGTHFILNPRVDDIPEQFCVDHAGIKLLLMGTVNHAGSGCVCPEHALVRTLLRHILTKRKECVLIDMEAGIEHFGRGTIEAVDLLVIVIEPGSRSLQTAAQIEGLARDLGIKTICHIANKLASPVDVGFILDRADQFDLLGSIPFDSAIQAADQAGLSCYDLSPACRDKAHALMAALLERVGPTQGVS
The following text describes a protein:
Function:
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAACPAATTARVGAAHGGGLWRRSGRSPSFPARPARGTSTAARASELQQAPAPAAAAAVPTHKVTVHDRERGVVHHFLVPQDQYILHTAEAQDITLPFACRHGCCTSCAVRIKSGQIRQPEALGISADLREQGYALLCVGYPSSDLEVETQDEDEVYWLQFGRYFARGPVDRDDYALELAMGDE
The following text describes a protein:
Function:
Has a tumor-suppressor role for NES1 in breast and prostate cancer.
Subcellular Localization:
Secreted.
Sequence:
MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN
The following text describes a protein:
Function:
Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSATVSTVSADLHKAIDAGDEDKITKITASYGSEQRDKIIPAYHANYGIPPSEAIRKAFKTGFYETMIVHAWTSRFELRAKLIHESIKGKIDVITLLDLVIACMPDDWYGTKVCYTKLYGRELVREIDEVIGVGTPWQSLVSGWVKHDRKYRKSIKSDAEAFRMALDSDNYEVLGSMLATSVPDEWMRIAAAYEETTGMPIDQAIASRYVKVDQTALILAHHWLCDPGQAAAYICSQCCAERKGNYARICRFTSMMYDHCLKCKYAYRAYGSLAMDIRKCFEPKLAKHLLVFWRVE
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MSVDFRKLKSFVKVVDAGSVSRAAGLLRTAQPAQPALSQQIAALESHFKHKLLLRSNHGIVPTEAGLILYRHAQLLLKQIEQAQIDIDQSNKALAGRVSIGLATYSASSTLSLPILKEMSTLHPQIIVHINDSFGHVLSELIMTGRMDMAMIYGSGPIKGVKLQPLFREELFLVSPAGPGAKKPADEPLPLSALANVKLLLPSQGHFLRRLIDESLARARVAPNVVSEIESVSALGAAVTEGLGSTILPASVAASASSFGGVEVRRLVRPAIEATVSLCISDHLPLSEPALATRSVLLTVVEKLMRSHPQGIRSV
The following text describes a protein:
Function:
Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.
Sequence:
MTGPTVLMVAEKPSLAKSLAWILSNHSATSRPSRSKSCTVHEYSGDFMGQQAQFKFTSVMGHVMSLDFLPQYNNWERTPPRELFDAETEKKDANPKAHVREALRSEGKGVDYLVLWLDCDREGENICFEVMDIVLPVMNRSVRGQTVFRAKFSAITEKDIKAAMRTLVAPNENESLAVDARQELDLRMGCAFTRFQTRFFQTFTPERYWTIDLQLEHDSGFLRAQWERVRVFDQELGRVFTNRVQEASSARVVSVSEKEKKKPRPNALNTVELMRVCSAGLGMGPQYAMAIAERLYMQGYISYPRTETTAYPENFDLVSVLKEQQNSPNWGKEVKELLAGAMVQPKGGKDVGDHPPITPMRVAQESDLGGDDWRVYDLVTRHFIATLSPDCKYLTTTIVLDAGGEVFTIQGSRTLSPGFTAVMHWVGSAEQQTVPSLPEGATLRIKSATLSDLISLMEKHGIGTDASIPVHINNICERNYVQIQAGRTLVPTNLGIVMIHGYKTIDPDLCLPTMRAAVEKQLDLIAKGQAPFDDVLAHFKLLFQRKFEFFEAFISNMDQLFEVTFTPLKSTGKQLSRCGKCNRYMKYVSAKPQRLYCPTCDETFALPQGGKIVLYKELRCPLDKFELLMFTTGTTGRAYPLCPYCYNNPPFEDMDKASGCNDCTHPTCEHSLIQLGVTQCECGGQLVLDASSKPKWRLCCNRCNIVIRLFENAHSIKITKTPCEACGAMEVDVEFNKTKNPLKDGTLTRQGCIFCHEDLAPLVELAHAQRMRSRGRGRGRGRGRGRGRRMPKGKEAQLANYFV
The following text describes a protein:
Function:
Involved in the biogenesis of the 60S ribosomal subunit.
Sequence:
MSIDSTLLEDASSSHRIYIGDSIGCLRVAQCDPPSALPKDYAGPSVKPLILPNFKSHSDHAVQRIASGVLGSDVYVVALARKNATIDVVHIANQSLPSTSTAPAPVSELRANIICTIQEPLMKAGIHRFVGLALSKHGVFTITSSGVLRYTPIAVTADHTPPVIEVREAKVLDHLPSPLQHASFYPAFDPTHFCYGGEDIPLSLWHIPTALSEQPTDSVADMSVESFKTEDVSELNSKQRKRKRQLEAKSKARELLWGEVWRAKNLANDNLSLPRRANITCTCILNLRDSTAQDGETGAVDETTFIAVGTKDGLVRVFQPGAGSRRHIREMRVIATGQGAVKTLCASSAALDGRRGGLLFVGDTGCKVYAVDWQSGKVVYGYKDGQVGATLCMVLLPGSVKCSNNEPEALVTVSSDSLVRLQSTVPAALAVPKAGASAEKGEVLWTKMIAPSTSHSVHATPTAVVWDGVLPPALNKRTVNSRENTPEDDDDEQDEVWASMQAVGEKRHNGRNARKNAKPNGNVQDDHVDNDDTEEEDDTDQEHGADPEARSAQIEVGKEQVKRRATHPAQPKRSRN
The following text describes a protein:
Function:
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
Sequence:
MMNEKHLQSLLICRLGGAALSEEAARELMEAWLAGEVPAALSGALLVAIAPLAITAGELAAMAKTLQEAAGAAPTGLPVLLDTCGTGGDGLGTFNISTAVAFVAAACGVPVAKHGARSASSRVGSADVLEHLGVHLSQERARVRAALDAVGITFLFAPGWHPALKAVAPVRRELGIRTVFNLLGPLVNPLVPTAQVLGVYHPSLVAPMAEALERLGRERFLVVHGGGGLDECSLTGPTALAGNLSGPICGSRLHPEELGLAAAPLEALAGGDVAENADILRRVLQGKGSRAQSEVVILNTAAALVAAGAAAGWMAGVTLARDCLADGAPWAKCEALIRFGNT
The following text describes a protein:
Function:
Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. In astrocytes, regulates sleep homeostasis by limiting the accumulation of serotonin and dopamine in the brain upon sleep deprivation. Is not essential for sclerotization.
Subcellular Localization:
Cytoplasm. Nucleus. Note=In astrocytes, is primarily cytoplasmic, but in neurons is also nuclear.
Sequence:
MEVQKLPDQSLISSMMLDSRCGLNDLYPIARLTQKMEDALTVSGKPAACPVDQDCPYTIELIQPEDGEAVIAMLKTFFFKDEPLNTFLDLGECKELEKYSLKPLPDNCSYKAVNKKGEIIGVFLNGLMRRPSPDDVPEKAADSCEHPKFKKILSLMDHVEEQFNIFDVYPDEELILDGKILSVDTNYRGLGIAGRLTERAYEYMRENGINVYHVLCSSHYSARVMEKLGFHEVFRMQFADYKPQGEVVFKPAAPHVGIQVMAKEVGPAKAAQTKL
The following text describes a protein:
Function:
Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN) to the plasma membrane.
Subcellular Localization:
Cytoplasm. Golgi apparatus, trans-Golgi network membrane. Membrane; Peripheral membrane protein. Note=Mainly localized to the trans-Golgi network (TGN) but also found at the rims of Golgi cisternae.
Sequence:
MEGVLYKWTNYISGWQPRWFVLEGGTLSYYDSQEDAWKGCKGSIKISVCEIQVHPSDFTRVDLIIPGEQYFYLRAINAAERQKWLVALGTAKACLTDNRTKREKELQENSEALKTKMSELRLYCDLLLQQVNKIQESPLAETSAGSGEGGDETGNLVKSTCTTFLKTLEECMHIASRTFNPDLLSRTPPGSPSVATIKPQKIKSNDPKNLHPGETRKDLINTSGTSAHESGPDNEPPPSPQENISTAHTESGLMEDQNDLIEPNNGSSSSTQDHEEPVEEQQTDGSTEDADHSQEEQQEVSMSPTQNKQEVQEDIQTDLELNETQSENKQEEEDEDKVDTFFSTMSHRFSDIILEEDSGIPTQAFLDSCYAIVPVLDKLGPTVFAPVKIDFVGNIKKIQQKVVSDPESFPTLQSIVLHEVKTEVAQVRNSATEALLWLKRGLKFLKEFLSEINTGVKDVQGALYNAYGKTLRQYHGWVVRGVFALALRAAPSYEGFMAALVSYEGDELKEGFRTGMHRDLDIYLPAMENQLSILDTLYEEYGLESDEIV
The following text describes a protein:
Function:
Required for cell growth and for the G2->M transition of the cell division cycle. Mediates a protein kinase cascade; it activates BCK1 which itself activates MKK1/MKK2.
Sequence:
MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNERCNSKEYGFLSTKSPNEHIFSRLDLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTLTSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQLMGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLRYTGFQCQDCKFLCHKKCYTNVVTKCIAKTSTDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGSSIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLPSVLTTSQQEEFRGFSFMPDDLDL
The following text describes a protein:
Function:
Required for a complete transcriptional response to osmotic stress, through recruitment of HOG1 followed by pol II recruitment to the promoters of GPD1 and other HOG-dependent genes.
Miscellaneous:
MISCELLANEOUS: Present with 149 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSGMGIAILCIVRTKIYRITISFDYSTLMSPFFLFLMMPTTLKDGYRMNSQVNEDAIGINLDLSLPTHISPTTGSESASGSNASTLRNDGNALDGGLLRTSAAISAPTGTSQPTETIGEKLSNEERVNSNVSASNSTTAGTGRMLSQSLTNDSPSNEISTDQLKIFQRMDEMSARMIEMEESFNKLSNKIAEQNTMVLNLKQDNYKVMNKLNILLKLVAQPSARPSTNNAQNKLAIELLNSISAVSSAYLQKMQNNGSGRQHTADLCTGDSNTHSGINQHRTTNGTIDVNTNTAQLNNQFSNALNTILPDQQHNRNNVSQNINQSLPNRQLGPVINTQANQNQSQVLIHNTNTHQQVNRSPISFPNASTDKPFKLNPNGIKRRRRNTQSNNNASTNDHASAAQKPISALSPLTNSHNSTTSMNYTNSSIHSGVTSASNSFHDLNSLNNFGTTTALSLPSLALDNASFPPNQNVIPPIINNTQQPLSFSQLINQDSTTSELLPSGKSGVNTNIVNRNRASTLPSYPKPMTVKSNVDDDGYQEDDDDDGDDEGDGRDNEEDSTAEEDEVDDEIETDMKNASINKRRRSLHHKKSNSLNGRRKLHGESATKPNINSDLHYRILKAPTDVKTIWEEYDTGIRGKPSIKHLEAKYGNKWRLNKNKKTFSRRKRLYKFILNGMERGKTAQEMIETLENKRLYKDDEDGEVKKRTIGWLQESLAGI
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Sequence:
MRIAVIGAGGVGGYFGARLAAAGNEVTFVARGGHLAAIRRSGLVVHSPLGELRTSPDSVVASISELGPTDLVLVAVKLWDTQAVAEELRTSPAHGAPVLSLQNGVHKDDVLRGRLTDEQVLGGVCFISAFIEEPGVVRHNGPLQKVVLGPYRSGSTATVRAVLAAFRDAGIDAEGSDDIERAIWEKFVFLVGLSATTATVRQPVGVVRANERSRRLLYEVMAETVAVAQASGVRLDSGFAEDRLAFCDTLPAAMTSSMHNDLEKGNRLELPWLSGGVVDLADRLDVPVPRNRTVADILAPYVLGRPAGS
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli neutralizes the effect of cognate toxin ParE1.
Sequence:
MGKNTSFVLDEHYSAFIDGEIAAGRYRSASEVIRSALRLLEDRETQLRALREALEAGERSGSSTPFDFDGFLGRKRADASRGR
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MSTDGRKTFMNSINKAEPMIVKWNLHIHETPPSSTKSVSIFYDFPEEALEFLTTVTDFNTAMEVYTNDESDATDIDKENILSRAGVLMKIAIQRLLKEFYHILEAKTLSSSDESSSDLENEGSDDRRFRTQDIADLRAIAECMVKLGYRKECVKAYKVTRISIIDEGMYRLGYDKLSKSQLQKLPWSSVEVRIRKWHKSLGMVIQTLFSDEKLLSEEIFGFSDSLKESCFAKISKVRASQFLAFPSLVTSTTKKSPEKIFLFLDLYDVITSEYSSEIKSLFFKSPAFAVVKSQVLLTVEKIGQTIRTMLGNFETAIRKDTCKTLVPGGGVHPLTRYVMNYVVFLADYTQAISDIYVDIPVANYKSSLLLLPDNLLRLVITPSSPTTCSDKDGENTGASGRLSWIIMILQSKLDAKSRFYRTPGLSYLFMSNNIHYILQKVRGSSRLHLLLGEDWEMKTKEKETNYIDSYVNVGWKKVIDAIAPEDPTTAISRMKEFGKAFEEVCRCQAEWVFANEKMREMVKVKVEENVVESYRPFYDECCKGNNQSDLKFSPEEVEKNIADLYSDNVDSST
The following text describes a protein:
Function:
Transcriptional repressor that negatively regulates neuron differentiation by repressing retinoic acid-induced gene transcription. Binds and interrupts RARA from binding to retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. Recognizes and binds 2 copies of the core DNA sequence 5'-CCCCCA-3'.
Subcellular Localization:
Nucleus.
Sequence:
MEEASLCLGVSSAVPEADAHLNSTILNGQYSMSQKLHQITSQLSHAFPELQNRQNPEEKASAPLEDKSHMSIANQPISSQMALLANQLNREVDTSLNGRVDLQQFLNGQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRDKQMKSSLLQPRPDVKAQQHAQPMPLTNCNLSVPANHSTPDISNPVPSPKPVSVQEEVVAQTAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGSNGSGEQSTNEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPNDPEVPVSISSMSQEAHANLYSRYLSCLQSGFLPPDKASLSEQNQIYNKGDMPMKEKEVLGKLLSPISGIGHSIAEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSKEQQIQRSHEDTLANAGVMFDKEKREYVLVGADGSKQKMPADLVHSTKMGNQRDLPNKLDPLEGSRDFLSHGMNQGLDYNLQSHGNVKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEDEIVQGSLDERRGSGSDQESQSVSRSTTPGSSNITEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSVGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQAANQEHKEETSSKSSVFIRPDILRGAFKGLPGIDFRSGMVSQQWTSGMLSSGDQQGQAAGMSSEVSSENMKGSDISSKGTHFSELGRAYQNMVGNGVNFQGSLQAFMDSFVLNSLKKEKEMKDKALSDPLSAKALGSDGGEEKISSKSSQRKTEKSQYEPLDLSVRPDAASLPGSSVTVQDNIAWHGCLFCSFTTSSMELMALHLQANHLGKAKRKDNIIGNNKEQSREAAASVNKVSLLSASVQSSKEAVVSNMLSQLDSASEKMTQGQNKETLGEQKSAAWPGHMESTFCNFTTDFYKQFGVYPGVIGTGTQNSCTSNESEIKPQSEDDPIILLSDSVNKSATDDLSDIASSEDMESSKEENIEDEDIETEPDIMNKQLSALNKESSEGGDNIQSAVTSQPAQGLVSPLPQASEKQWHSQNLLSSHETAQGVMKPEQVQGPQVLEKQMNMLSVLRAYSSDGLAAFNGLASSTATSGCIKRPDLCGHRPFQCRYCPYSASQKGNLKTHVLCVHRMPFDNSQYPDRRFKRSRADSEAPGSLEDAAGRTAGPAEQAEEGGHGLE
The following text describes a protein:
Function:
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSPSATDTTEVMDPTILTLRKVLTSESEPLGRRFRALFSLKHLACLQPPTEKTLPAIQAIAAAFTSPSALLKHELAYCLGQTRNPASLPFLQQVAKDTEQDTMCRHEAAEALGALGYEDSLEILKALRDNQNEPEVIRETCDIAVDRILWENSEARKAEKLKTSDFTSIDPAPPLPMTASEPSIPEIEQTLLDTSLPLFLRYRAMFALRDLASPPDLPTATRAVEALAKGLKDPSALFRHEIAFVFGQLCHPASIPSLTEALSNQSEAGMVRHEAAEALGSLGDYEGVEETLRKFLNDPEQVVRDSVIVALDMAEYEKNGEVEYALVPDAGVAAA
The following text describes a protein:
Function:
Involved in spore wall assembly.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKVQMIERIFLIQLCLLTVVLASSRAVVEFESTGTKLVNSLRVLAAYSQSSVCVDEKISGIERQIEEVKDMYGNHSFILKGLNGILNNKVNMLTREIQMETVGNNTFETETGKLTKGLNRAVNISPFKYIKKFKTVSTKKFESLLNKYDLVAKKGGELTEEQKKKKEVLSRISRVVAATTIEAGLAQGVVDLCITVTTSLCLVSASIGGVGFLIWLTIIYQALT
The following text describes a protein:
Function:
Viral mimic of EIF2S1/eIF-2alpha that acts as a pseudosubstrate for EIF2AK2/PKR kinase. Inhibits therefore EIF2S1/eIF-2alpha phosphorylation by host EIF2AK2/PKR kinase and prevents protein synthesis shutoff. Determinant of host species specificity.
Domain:
The C-terminus is involved in the inhibition of host EIF2AK2/PKR kinase.
Sequence:
MLAFCYSLPNAGDVIKGRVYEKDYALYIYLFDYPHFEAILAESVKMHMDRYVEYRDKLVGKTVKVKVIRVDYTKGYIDVNYKRMCRHQ
The following text describes a protein:
Function:
May have a central role in the fusion process during myogenesis, within the somatic mesoderm.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Note=Enriched in the embryonic membrane fraction.
Sequence:
MQLFDDFCKSFNKELQRANFGFAYNRVHLFYRSQWQKDEINTIYLLYRWIWALFFLGVYIMCVIVQFCDGKFFIYMTNWGFGLCTITMLISAVQVTCWHFDVRSTRSLVQESGHKAETSRGLKIYWWLYNMTLSLALIISTVYWVFLHGKMNKPMRFPAISIITHGMNSVMMLIDFLVIAFPLRILHMVYGMSLAIFFFLFTLIYHLCGGTDEFGNHYVYPILDWNNPNRCMVTFVGIFLLIMCYWVLLFGLYKLKRMFNRAFSVVWSPHAVGLI
The following text describes a protein:
Function:
Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
Subcellular Localization:
Endomembrane system.
Sequence:
MSKLYKAQTEMVHTWEFTAFIRAVGEARSKQEEDEIIQRDLGNLRKSFETAHVEDWLLKEYVVRVLYAEMLGHPAKFAHIHCVNLSASPDLLVKRTGYLGTWLTIAPQEDIMILIVSNLLRDMNSCNFLHTAAALTAASKVVRRDLICAIKPEVVKLLDHSAPLVRKKAVIALHALYRNTADLIDYKNFFLRALGDPNPAVEAAALSPLLDIVQTNPELCRDLTETFIKVLEKVVSRRLSGDYEYQRVPGPWFQIQVMRILAALVCDSRELAAKCEYVLTEVITRADTGSTIGYAVACEAISLITRIPTIPSLIELSVETTAKMFATRNVNLRYTAIQALSNLACINTDYLRRHQEDILECLGDGDEMIRRKTTFLLLSMCNEGNVDIIVKKLIKYLNSQIDKYVLQELTQSICRTVERFSMRRLWYISTMNRLLLCAAEHVPYSSIQGMLKLIVEGGESGDEASDVAFRLRCVEDYFGLISCSQKKMPDALCRVAAWVVGEYGFLATAINRRLMVDGLCDLFARTDSGDARDWIIMAVMKIVASDGVVPENVKELIERFKDSRIATTQQRCYEFSRLTQMLPLMKRSLPLDRCCEEVDIEETLSFLNPFVQKALLGGAKPYEKRPVCREVRMEIPLCIEKYETPQLKTSEASLTCEVCDTEAKPPELAIRPSTRRWGAKTGNAAAMVNTGLAPDSHMREVGGGERITLSAQVARTGATLDEPCGVFGPQCDQSLPATPPTLGTKCSKNKKLLEDIFDASVQLKKYPHVAQQVPDLFEAVEVENKKNLAGENGSALSVHMEHVREERAVGITLFIVGNVTVNDLVVNVLPPSNCTLHVTSHSVQSAKLTGSTTITMETLKVNQSLEVVMQLLLTGFPNDMHVRVKVVYRRSEPFDMIDVGKSESKTATMTLQVGDFLRPASSMTTDTFGEMWLKYIGEYKTTLHGTAALTLESISQLLMERASLRVVEMIGNELIVAAVLPGTDQLLLGHVVLVDHHCANATFRAQDKRLAEFVVRSLDSAIPLS
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Independently of its E3 ubiquitin-protein ligase activity, acts as an inhibitor of CPSF3 endonuclease activity by blocking CPSF3 active site.
Sequence:
MTELTSCKTRGVGVFWELRKRLLSGLLIVRKEVAGAADDVLVTGGGSSLVVRTPRGQLELALPAGVSFTEGSCIPTPGESSAEELHFRLRITVEQSSHKEASDCVTESLRAKETYCFYCQGCMTRLLEDRVFKRVLPLPNGSWNAIVDDWCCHPDPFANKKLLPRAEDCLLGDTFVLLARDSSCTQTLTEEVSPVGTEHTQDQKKACRRVTFISCASCSSVLGEAVSPEALKLYITQVVVEPAVGDPKPEAAQSRFHFLERTIATRLLNLSNSLSTFHFSVQTPDGNAFLLLWLLNSDSIVASVPEKCVGNDSSSAVHSSPLRAARALKLLYITCSDADVPQREVVSHWEASIIAHPLVLPLSVCEELQRVINHSNSELPSSMRCMRSYEVAYLRL
The following text describes a protein:
Function:
High affinity carnitine transporter involved in the active cellular uptake of carnitine. Also transports organic cations (By similarity).
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MESPEDRNGNDVRQPLLEKIPVKKEAEGEERLCIDEMLQRYCGEFGRWQLKHFVLTCIAWALEAFHTMVMIFADQEPEWRCVGSDCRVGSLNCELDPSSWEWTAGKGSSTVSEWGLICGDKYKVGLVQALFFAGCMIGAGVFGHLSDSKLGRKGSLTVVCIINAIFGIATAFSPNYWTYVVLRFLTGFSTGGVGLTAFVLATEPIGPSKRGVAGMSTFYFFSAGIAVLSGIAYVFRSWRELFIVSSLPSLLFLLIVIPFISESPRWYLVRGKVDEAMKLMHSIAKTNGRHIPAGVTLALDDDVENNNGERNTAVEGSLKDVILSPLMRMRLVISVAISFTVSIVYYGLSLNVGNLKTNLYLNVFVNAVSEMPAFAITAVLLDKYGRKPLSIGTQWFSCVFCLVGFSVWGAGPWKSVRMVSGVLGIFGMAGTYNLLFIYIAELFPTVVRNAALGCATQAAQMGAILAPFVVVLGEELPFGVFAVCGLVGGGLAFYLPETLNKPLYDTMFGMHEAESESNRERGEVIC
The following text describes a protein:
Function:
Glucoamylase that hydrolyzes alpha-1,4-glucosidic linkages, alpha-1,6-, alpha-1,3- and alpha-1,2-glucosidic linkages during starch degradation.
Subcellular Localization:
Periplasm.
Sequence:
MKKRKILSLIAFLCISFIANAQQKLTSPDNNLVMTFQVDSKGAPTYELTYKNKVVIKPSTLGLELKKEDNTRTDFDWVDRRDLTKLDSKTNLYDGFEVKDTQTATFDETWQPVWGEEKEIRNHYNELAVTLYQPMNDRSIVIRFRLFNDGLGFRYEFPQQKSLNYFVIKEEHSQFGMNGDHIAFWIPGDYDTQEYDYTISRLSEIRGLMKEAITPNSSQTPFSQTGVQTALMMKTDDGLYINLHEAALVDYSCMHLNLDDKNMVFESWLTPDAKGDKGYMQTPCNTPWRTIIVSDDARNILASRITLNLNEPCKIADAASWVKPVKYIGVWWDMITGKGSWAYTDELTSVKLGETDYSKTKPNGKHSANTANVKRYIDFAAAHGFDAVLVEGWNEGWEDWFGNSKDYVFDFVTPYPDFDVKEIHRYAARKGIKMMMHHETSASVRNYERHMDKAYQFMADNGYNSVKSGYVGNIIPRGEHHYGQWMNNHYLYAVKKAADYKIMVNAHEATRPTGICRTYPNLIGNESARGTEYESFGGNKVYHTTILPFTRLVGGPMDYTPGIFETHCNKMNPANNSQVRSTIARQLALYVTMYSPLQMAADIPENYERFMDAFQFIKDVALDWDETNYLEAEPGEYITIARKAKDTDDWYVGCTAGENGHTSKLVFDFLTPGKQYIATVYADAKDADWKENPQAYTIKKGILTNKSKLNLHAANGGGYAISIKEVKDKSEAKGLKRL
The following text describes a protein:
Function:
Involved in the biosynthesis of theobromine. Catalyzes the conversion of 7-methylxanthine (7mX) to theobromine but not able to convert paraxanthine to caffeine.
Sequence:
MEVKEMLFMNKGDGENSYVKTSGYTQKVAAVTQPVVYRAAQSLFTGRNSCSYQVLNVADLGCSSGPNTFTVMSTVIESTRDKCTELNWQMPEIQFYLNDLVGNDFNTLFKGLSVIQDKYKNVSCFAMGAPGSFHGRLFPQNSMHLIHSSYGVQWLSKVPKMTSEGGLSPPNKGKIYISKTSPPAVWKAYLSQFQEDFLSFLRCRSPELVPDGRMVLIIHGRKSADPTTRESCYTWEVLADAISYQVSQGLIDEEKLNSFNVPYYIPSQEEVRDLVNKEGSFLTEFVDTIEVELEGIWTGPENGAKNLRSFTEPMISHQFGEEVMDKLYDKVKDILVEDCKQEKQSTRGVSIVLELKKKESHLS
The following text describes a protein:
Function:
Protein kinase that plays an important role in mitotic regulation. Seems to be phosphorylated and thereby activated by CDC2/cyclin B during mitotic activation. It is also required for spindle formation and for nuclear envelope breakdown.
Subcellular Localization:
Nucleus.
Sequence:
MAIALAEADKYEVLEKIGCGSFGIIRKVKRKSDGFILCRKEINYIKMSTKEREQLTAEFNILSSLRHPNIVAYYHREHLKASQDLYLYMEYCGGGDLSMVIKNLKRTNKYAEEDFVWRILSQLVTALYRCHYGTDPAEVGSNLLGPAPKPSGLKGKQAQMTILHRDLKPENIFLGSDNTVKLGDFGLSKLMHSHDFASTYVGTPFYMSPEICAAEKYTLRSDIWAVGCIMYELCQREPPFNARTHIQLVQKIREGKFAPLPDFYSSELKNVIASCLRVNPDHRPDTATLINTPVIRLMRREVELNNLSRAARKREEATMQKAKDVEQAFAKLEKEKQQIRSELENSIRREWEVKARLEIDRQVQNELDKLRKRFECEVQDRVAQEVEKQRRNANYREDASLRSSGHSSQMSSSNSEDSDFPSSTDISQLSLESPTNKAAKLPKKESRTPFTRSKTVVDSPMDIQMAEPSPISIASLSLSPRRTSATYSGKNIFAEGERKRPKFEPTLAYSDDEDDTPELPSPTRPKVKPDPFKAPSRPLLRQNTTALMQKLSTQPPIFPANPSRLPQMSAPDVRESKSRSPHRRLSKIPSSANLAADAGSPTRKNGVKSSPSKMNGGDEMFKAVMQRNMGGRTLVELAQARAGGRPIDEVKRCASDSRSGCSVPMKSADRDPPAVWDPERDEMPSPFLARGRKVIRNLR