lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Sequence:
MGSFWRGLARPLYCVAPMANVTDAPFRRLISEISKPSVMWTEFVSCEALTHDPGSRRRMMTTLKYAEQERPVVAQLFGSKPEQFYEHSILHPTPLLTLAIANCQSAMIVRDLGFDGIDINMGCPETNVNNQGSGASLILQPELAVEIVAACKRGAGDLPVSVKTRIGFHHIDYKDWVLRLLATEPEVLTIHGRTRDEMSKVPAHWDVIGEIVTLAKAAGSPALILGNGDVSSLVEAQQKVDEYGVDGIMFGRALFGNPWLFQGYPDTSHVPVKEKLEVIQRHTQLFQEMLGDPGLVGFQRMKKFYGSYLKGVPNARQLRDRMARTQTPQDVYTIIDEALEYLAAQELQEQLQAES
The following text describes a protein:
Function:
Involved in ceramide synthesis.
Subcellular Localization:
[Isoform 1]: Golgi apparatus membrane; Multi-pass membrane protein; [Isoform 2]: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MLTPMVAGGVVFPGLFLLSKNTLQRLPQLRWEEADAVIVSARLVSSVQAIMASTAGYIVSTSCKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGGDDGAARAPGSTWAIARGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLPLLAVPLAIPAHVNLGAALLLAPQLYWFFLICRGACRLFWPRSRPPPACQAQD
The following text describes a protein:
Function:
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
Subcellular Localization:
Nucleus.
Sequence:
MAFHFECLDIKLVCLIFVFIVFEIKKHQLPIARIKRIMKSDEEVKKISADAPILFSKACELFILELTLRSWLHTEEQGRRTLQRCDIAHSITTESVLDFLLGVIPVEETKEEQAEKDESLTVSDLPSNEVSLPMIDVNKFHQNLNGKFKAGEQVPQRLMIQHPESSTRIVYESPAESRDIKNGEKQGEAIDLCYGSKDGI
The following text describes a protein:
Function:
Involved in the modification of secondary bile acids into iso-bile acids (3beta-bile acids) via epimerization of the 3-OH group through a 3-oxo-intermediate. Catalyzes the reduction of 12-alpha-hydroxy-3-oxo-5-beta-cholan-24-oate (3-oxo-DCA) and 3-oxo-5-beta-cholan-24-oate (3-oxo-LCA) to yield isodeoxycholate (isoDCA) and isolithocholate (isoLCA), respectively. Is also able to catalyze the reduction of 3-dehydrocholate (3-oxo-CA or 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate) and 7-alpha-hydroxy-3-oxo-5-beta-cholan-24-oate (3-oxo-CDCA), into isocholate (isoCA) and isochenodeoxycholate (isoCDCA), respectively. Accepts both NADPH and NADH as cosubstrates. The conversion of the abundant bile acid deoxycholate (DCA) into isoDCA by the gut bacterium R.gnavus favors the growth of the keystone commensal genus Bacteroides, since isoDCA is less cytotoxic than its parent compound, DCA; iso-bile acids have thus a potential role in modulating gut community composition.
Sequence:
MNFGGFIMGRFDEKIMLVTGATSGIGRAVAIRAAKEGATVVAVGRNEERGAAVVAAMEEAGGKGEFMKCDVSNKDAVKALFAEIQEKYGKLDVAVNNAGIVGASKTVEELEDDDWFQVIDANLNSCFFCCREEVKLMQPSGGAIVNVSSVAGMRGFPSAAAYVASKHAVSGLTKAVAVDYATKGITCNAICPAGTDTPLTERSSADIKTRMAEIAAQGKDPMEWLKNSMLSGKTETLQKKNATPEEQAATILYFASDEARHITGSIVASDGGFTTY
The following text describes a protein:
Function:
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
Subcellular Localization:
Mitochondrion matrix. Nucleus.
Sequence:
MYTISRLVNSNVVRSKVPVRWNSAHKKLNKLLSKMPLDPKHIAEAQKQRLKLKQKVSKVSPGIVNLQVLGCGAPGTPASVYLFTDQTRYLFNCGEGTQRLAYEHKTKLSCLENIFMTRTNWERIGGLPGICLTMQDVGVPAVSLHGPPGLDELFKAMRRFVILKDMKVEASEYATGDVYEDHVMTLRYVVINRQPASGAREAGSDEDQNQDEATVDDTDYYAYERKRETLQKPQSEAVKSVQSTNWTKREESSVMAYICKLKPRHGQLSLEKCVELGVPPGPLLGQLKNGNDVTLPDGRVVRSCEVRAPDDPGPVFMFIDIPSREYMDDFVAKAELFEKYQQTAAEESDQAIFVVHFSPLDVMRCDEYRQFMDRFSASTRHIALNEVNSFSGYIAAHRIQYHLNQLDEQIFPLLREENNQYADPPANDTDLVRSSSLSYMHIRPPKGIDRTLEASLNPQEYLNELELLPDFKEALAELKQQLAQHTARRSAAVRAEQFPRLIFLGTGSSIPNKTRNVSAILILTSKQSSILLDCGEGTVGQIWRVFGKEQAEEILRSIKTVYISHLHADHHLGLIGLLQARKKLLGDNCECLTLVAPEQISYWLRLYDCRFETIHKDYVLVKNADLLENPLQDEKLLAVGIKEIATCRVRHCPHSFGVALKVASLGTHPETNIEGDVKITYSGDTMPCESLIELGRDSTVLIHEATMEDELAAEARIKMHSTLSQAIEQGRKMNARYTLLTHFSQRYAKIPRLRPDQQQTGLGTDLGIAFDNMEVTLDDLPTLCKFYPALKAMFISHFEEMEQKAIKRGNKKLRLETVKTATGSKECSPTR
The following text describes a protein:
Function:
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. Acts on the two major protein phosphatase 2A catalytic subunits, PPH21 and PPH22.
Sequence:
MERIIQQTDYDALSCKLAAISVGYLPSSGLQRLSVDLSKKYTEWHRSYLITLKKFSRRAFGKVDKAMRSSFPVMNYGTYLRTVGIDAAILEFLVANEKVQVVNLGCGSDLRMLPLLQMFPHLAYVDIDYNESVELKNSILRESEILRISLGLSKEDTAKSPFLIDQGRYKLAACDLNDITETTRLLDVCTKREIPTIVISECLLCYMHNNESQLLINTIMSKFSHGLWISYDPIGGSQPNDRFGAIMQSNLKESRNLEMPTLMTYNSKEKYASRWSAAPNVIVNDMWEIFNAQIPESERKRLRSLQFLDELEELKVMQTHYILMKAQW
The following text describes a protein:
Function:
Required for the biosynthesis of polyacyltrehalose (PAT) and the transport of diacyltrehalose (DAT) and possibly PAT to the cell surface.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MVGCWVALALVLPMAVPSLAEMAQRHPVAVLPADAPSSVAVRQMAEAFHESGSENILVVLLTDEKGLGAADENVYHTLVDRLRNDAKDVVMLQDFLTTPPLREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKRTVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMIAGAGTDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRGWVAPRGERMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPPSDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPRGLADLEQLAQRVSQIPGVAMVRGVTRPNGETLEQARATYQAGQVGNRLGGASRMIDERTGDLNRLASGANLLADNLGDVRGQVSRAVAGVRSLVDALAYIQNQFGGNKTFNEIDNAARLVSNIHALGDALQVNFDGIANSFDWLDSVVAALDTSPVCDSNPMCGNARVQFHKLQTARDNGTLDKVVGLARQLQSTRSPQTVSAVVNDLGRSLNSVVRSLKSLGLDNPDAARARLISMQNGANDLASAGRQVADGVQMLVDQTKNMGIGLNQASAFLMAMGNDASQPSMAGFNVPPQVLKSEEFKKVAQAFISPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQPNTSLADASISMSGYPVMLRDIRDYYERDMRLIVAVTVVVVILILMALLRAIVAPLYLVGSVVISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAVGADYNMLLASRLRDESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIDTFVVRTITVPAMATLLGRASWWPGHPWQRCAPEEGQMSARMSARTKTVFQAVADGSKR
The following text describes a protein:
Function:
ADM function is mediated by the CALCRL-RAMP2 and CALCRL-RAMP3 receptor complexes with ADM showing the highest potency for the CALCRL-RAMP2 complex.
Subcellular Localization:
Secreted.
Sequence:
MLCCKKNNKIIRVQMCALSSLRTVGDPGMEIAFLLLLTVSLTTAGPLKLTPKRESEVGVTFFGTPVQTGATGRADKDAPPLKVVPFHSEGKRFGLEPLKQSALILRLRRALQRGCQLGTCQLHNLANTLYHINKTNGKEESTKAHDPQGYGR
The following text describes a protein:
Function:
Contributes to the intracellular multiplication of tobamoviruses, probably being a membrane anchor promoting the formation of the replication complex.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MRIGGVEVTKFASEMMSSSSSSAVEMLNLKEASNWWSDVNESPIWQDRIFHVLAVLYGIVSLVAVIQLVRIQLRVPEYGWTTQKVFHFLNFVVNGVRAVVFVFRRNVQFMQPEILQHILLDIPSLAFFTTYALLVLFWAEIYYQARAVSTDGLRPSFFTINAVVYVVQIALWLVLWWKPVRVMVILSKMFFAGVSLFAALGFLLYGGRLFLMLQRFPVESKGRRKKLQEVGYVTTICFTCFLIRCIMMCFAAFDEGANLDVLDHPILNFIYYLLVEILPSSLVLFILRKLPPKRGITQYHQIR
The following text describes a protein:
Function:
Sequence-specific DNA-binding protein that interacts with enhancer elements to regulate transcription of selected genes (By similarity). Required for neuroblast and epidermal morphogenesis, perhaps acting in cooperation with transcription factor aptf-4.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Localized to both cytoplasm and nucleus in most cells, but significant nuclear enrichment in neuroblasts and epidermal cells in AB lineage during ventral cleft closure and in epidermal cells in C lineage preceding dorsal intercalation.
Sequence:
MDIQMFTTLNSTVPTEPVVGPVEPTVPTVPATKETGPSSSAECSTQPAVAEQEDNSLLAQLLKGKITSDDAKLQPPRGPFEYAPMLSEEAQFAIKLAGLLNPNPVTEQDPSTFKPPPKMSNNVRKNINLTPVIENAVPSGFELESPKDQAFDVVHGRLSMGQNQTCYFVTVEEMRRRLQSPEKLNSSSIACNLKRPKLKNGGELMRAQLRDHGIKVQLNAKQKAFPNKVIALVEAEAVHLGLDLGTAVRDDYPVQDIIQEVAHEALADEDADLDALMNDKDFTECMSALESVFTSVVPPITGIEPKPSNNMRLNNGMETFSSASHGLGIVSQRVWLPQLTAIGNGVASELRRLTETPTESKPEELKA
The following text describes a protein:
Function:
Inhibitor that slows proliferation of secreting cells (also known as chalone). Requires aprA for activity.
Subcellular Localization:
Secreted. Note=Concentrated in subcellular structures, possibly vesicles.
Sequence:
MNKFILLLSLVTLSCVLAVPQLPAAQQYYMKGSFNIPYFNIVEPIELIYDSVNNRQYISVYNGMDITINFYNQDNTYNVGPVKYDMVCTTTPGNGSLVNVLPTEPSSWVYNGTSTVNGVQVFGYSQKITQYGRTGFYNFYVDANGVPVQFYMDGVDYVFGSHPDVYVLNFDIYTTDISSYESYFDIPVLCNNAKEAPAKENQFDGLFSSIGDNLLAKEEQASNLFKEYKAQYNKEYSSQDEHDERFINFKAARKIIATHNAKESSYKLGMNHYADLSNKEFNTLVKPKVARPSVTGADSVHDDESLRSIPSTVDWRNQNCVTPVKDQGICGSCWTFGSTGSLEGTNCVTNGELVSLSEQQLVDCAILTGSQGCGGGFASSAFQYVMEIGSLATESNYPYLMQNGLCRDRTVTPSGVSITGYVNVTSGSESALQNAIATTGPVAIAIDASVDDFRYYMSGVYNNPACKNGLDDLDHEVLAIGYGTYQGQDYFLVKNSWSTNWGMDGYVYMARNDNNLCGVSSQATYPIPTKN
The following text describes a protein:
Function:
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTEVMGGPESRGVLRKMSDLLELMVKRMDALARLENSSELHRAGGDLHFPADRMPPGAGLMERIQAIAQNVSDIAVKVDQILRHSLLLHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTAAQRAPKPLPKVQAVFRSNLSHLLDLMGSGKESLIFMKKRTKRLTAQWALAAQRLAQKLGATQRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILTALYVLGHGLRVTVSLKELQSNLGVPPGRGSCPLTMPLPFDLIYTDYHGLQQMKRHMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETEKRLIKGGKASNMAVVYGKEASIWKLQGKEKFLGILNKYMEIHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSEEFEAAIKAIMRTQVDPYLPYEYTCEGMLERIHAYIQHQDFCRAPDPALPEAHAPQSPFVLAPNATHLEWARNTSLAPGAWPPAHALRAWLAVPGRACTDTCLDHGLICEPSFFPFLNSQDAFLKLQVPCDSTESEMNHLYPAFAQPGQECYLQKEPLLFSCAGSNTKYRRLCPCRDFRKGQVALCQGCL
The following text describes a protein:
Function:
Functions as a v-SNARE responsible for targeting AtELP-containing vesicles from the trans-Golgi network (TGN) to the prevacuolar compartment (PVC) and mediates liposome fusion. May be also involved in retrograde traffic to the cis-Golgi (By similarity). Promotes the formation of vacuolar membrane 'bulbs'. Necessary to deliver proteins to the lytic vacuole, but seems not involved in storage proteins transport. Required for amyloplast sedimentation in the endodermis during shoot gravitropism, which are thus acting as statoliths. Expression in the endodermis is essential for the shoot gravitropic response, whereas expression in other tissues may be responsible for the correct stem and leaf shape.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Prevacuolar compartment membrane; Single-pass type IV membrane protein. Vacuole membrane; Single-pass type IV membrane protein.
Sequence:
MSDVFDGYERQYCELSASLSKKCSSAISLDGEQKKQKLSEIKSGLENAEVLIRKMDLEARTLPPNLKSSLLVKLREFKSDLNNFKTEVKRITSGQLNAAARDELLEAGMADTKTASADQRARLMMSTERLGRTTDRVKDSRRTMMETEEIGVSILQDLHGQRQSLLRAHETLHGVDDNIGKSKKILTDMTRRMNKNKWTIGAIIIALIAAIFIILYFKLTK
The following text describes a protein:
Function:
Involved in cytokinesis and septation where it has a role in the localization of F-actin.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
SRNPLKRLSKPSTRTSPGGELDEKTVEEYVSKFVRLETDTKKLHKDAKKYEDAMLALYHCEKKMSSDLANGELCNDNPELRRLVEEWLSFASSMDSAVDDHLVAIRRCLVDPLKRYQTVFTEVQAALKRRNQVAQECVRLEQRAERLAGRETTGPNLAKLSECKQALEAARGDLRTQGALLAQDLPRWYQASNLYLQPCLEALMHSQTLHWGQATTCAHNLLAPGAKVPVEQRLAAVRALSIVALPS
The following text describes a protein:
Function:
Involved in chlorophyll synthesis and chloroplast protection against oxidative damage.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MTVLVEPEVHDIFARIPGFGFVQTFYSQDTSDLHERVDFVACLGGDGVILHASNIFRGAVPPVISFNLGSLGFLTSHPFEDYKKDLRKVIHGNNTLDGVYITLRMRLRCEIFRSGKAMPGKVFDVLNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLFTPICPHSLSFRPVILPDSAKLELKIPEDARSNAWVSFDGKRRQQLSRGDSVRIYMSEHPLPTVNKSDQTGDWFHSLVRCLNWNDRLEQKAL
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MKKIAYLLLTISFCGLTACKTGTKKGGNMDNETLVKIETTLGDIKVKLYNETPKHRDNFIKLAEDGVYEGTLFHRVIKDFMIQAGDPDSKNAPKGKMLGAGDVGYTLPAEFVYPKYFHKKGALSAARQGDNVNPKKESSGCQFYIVTGKVYNDSTLLGMESQMNENKINVIFNTLAQKHMKEIYKMRKENDENGLYELQEKLFAEAEAEAAKQPEFHFTPEQIEAYTTVGGTPHLDGEYTVFGEVIEGMDIVDKIQQVKTDRSDRPEEDVKIVKVEVLD
The following text describes a protein:
Function:
Catalyzes the conversion of pentalenene to pentalen-13-al by stepwise oxidation via pentalen-13-ol, a precursor of neopentalenolactone antibiotic.
Miscellaneous:
MISCELLANEOUS: S.avermitilis does not produce pentalenolactone itself in vivo but instead a group of new metabolites that are neopentalenolactone derivatives.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MSQHTFVAGTAPGAVPVVGHAWQMMRRPLHFMSSLSAHGDLVKIRIGPTSAYVPCHPELLRQVLTNDRVFDKGGVFYDRARDIAGNGLVTCPYRDHRRQRRLMQSAFQRTQLERYSTAMRAEIDATAARWHDGTVIDAFPELYGMALRTVARTLYSTPVTEELAQRVEQAFDTVLNGLFRQMFLPHSLRRLPTPANLRYRNNLRFLHDTVQDLITEYRRDDTQRDDLLSALLASRDEDGGRLGDTEIHDQVITVMAAGTETVAGTLTWIFHLLSRHPEIEARLYEEIDTVLDGKPPHWDDLPSLSLTDRIITEALRMYPPAWIFTRLTASDVDLAGVRLPEGTTIVFSPSSVQRHSEAYDDASRFDPDRWLPDRTSAVARQAFTAFGTGARKCIGDLFARTEATLALATMLSQWRVTVEPDADVRPVALATVYHPRRLRLRLTARTPGQ
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MEVLLKLPSSESPLKDKFGSVQIHEANKGDGDHQELESAKAEMSEVKEENEKLKGMLERIESDYKSLKLRFFDIIQQEPSNTATKNQNMVDHPKPTTTDLSSFDQERELVSLSLGRRSSSPSDSVPKKEEKTDAISAEVNADEELTKAGLTLGINNGNGGEPKEGLSMENRANSGSEEAWAPGKVTGKRSSPAPASGGDADGEAGQQNHVKRARVCVRARCDTPTMNDGCQWRKYGQKIAKGNPCPRAYYRCTVAPGCPVRKQVQRCADDMSILITTYEGTHSHSLPLSATTMASTTSAAASMLLSGSSSSPAAEMIGNNLYDNSRFNNNNKSFYSPTLHSPLHPTVTLDLTAPQHSSSSSSSLLSLNFNKFSNSFQRFPSTSLNFSSTSSTSSNPSTLNLPAIWGNGYSSYTPYPYNNVQFGTSNLGKTVQNSQSLTETLTKALTSDPSFHSVIAAAISTMVGSNGEQQIVGPRHSISNNIQQTNTTNNNKGCGGYFSSLLMSNIMASNQTGASLDQPSSQLPPFSMFKNSSSSSSTTNFVNKEEKS
The following text describes a protein:
Function:
May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEEEANTSRTLLEDKDVSVVYSEVKTQHPDNSAGKISSKDEES
The following text describes a protein:
Function:
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAEPEGEPLENHNSDNSLPLGYFFHCLSLLIEMIVLFCRMLYHVLCSLYRFVFPASPKYVYGRTVLITGSANGLGRLLAQEFARRGAQLVLLDIDIEGNKLLAEELCSKGRSAHAYYCDLSRKTDLYSVIAQIKRDIGHVDILINNAATLSGKPVLQCSDSAIEKVFEVNTMAYIWLTKALLPDMLNRKQGHVVNIASLAGFVGVNGLADYCASKSAIIGFTEALGYELKQMKATGVHLSLVCPSYMEEGMFAQCKSRFPAPLKSERAVKMILQGILTNQKRIFVPWYAQYIPAVKSVLPVSAFTALLDFSGGGGVSFLRNFKGPRKS
The following text describes a protein:
Function:
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
Sequence:
MSRPTGACPHAWRHQQQPLRGRMWAASPAFRRQLVLLRSLLPSPPAPSSVAGFPPSCPSCSSFLRVRTNHAMAASAGTVYEADAEAVVRRITPPLDRARHKGQAGKIAVIGGCREYTGAPYFAAISALKVGADLSHVFCTKDAATVIKSYSPELIVHPILEESYSVRDDERASVSSKILTEVGKWMERFDCIVVGPGLGRDSFLLDCVSNIMRHARQANIPTVVDGDGLFLVTNNLSLVEGNPLAILTPNVYEYKRLVQKVLNCDVDEETASEQLITLCQKIGDVTIMQKGKADVISDGKTVTQVSTFGSPRRCGGQGDILSGSVAVFASWARHFVLTNEQPTEKRVNPMTLGCIAGSLLLRKAASHAFEKNKRSTVTSDIIEFLGKSLEDICPAEH
The following text describes a protein:
Function:
Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSAEESITQTAIAAHEFVQLYYALFQSRVDELLKMYHQQAVSNWNGNFFSGIAQIRNHLISLTPGKYDIETYDSQPIGDLAQGGSLLFIVTGRVKYNNNENNSREFYHQFILSRSSENVWFIVSENFRLLR
The following text describes a protein:
Function:
Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSQGQGGITLDELIAQADYLKRYIDSLQRTQLELLESINSIDSAKQAIETMKSGNKEMLVFIDRKGYLLAKVGGIIGDKVTVHLGLSYYAEVDLDSAIKILDKRKDEISKAAQDLNNELQKAASTYNQIVDILNQIQQAAARRQQGE
The following text describes a protein:
Function:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle. Nucleus.
Sequence:
MANAVELDFSDEQWAHEMLTKLVDQHVSLSNALEDLRPLLYGSSEDKERALERLVALVLKLPSDFLTEDQIHLLLSFFLDRLDTSGLAATRVIDAIRHLLIESKRTSKDAALLSWKSLYQEGNVQAWSVNQRLVLYEILEWLCTKQKSATLPIGSEFVLSFIKSIGGERDPRCLSIAFRLFVLISKEWSLGPFIEEMFETIACYYPIQFKPKGDQSITKESLSIQCELCLLSHSGFAPFCFLMIEEKLTEDGMEQSMRGEVCAFLSRAVSAFPASSLPPHSESLLSAIRAVTFDPNDKYGDNAAIAAESMRRIMLKLNQLDCRHVNAAIDHTMENIEPFVLQAEMGVSLRAFDLLETLCLPSSSASNKDGTQLLQRNELYLDGSVGECVPSVRSVVSRSISWALALVQGETTNTAANKGDVCKDGLEALVKWIEVTTKVGCQDEIVKMERTILASIDSVIPLVGREARVMEYGAAALMIAMNKEEGRIDDQYCELLKRGLYSIEMDMEERKAFLSFVTAHSFVRWNLHQSIISQAISLGEETTEQFALNRIDVLCASVHSENSWETLSGRIWNELEVVSEEGSHILLEFVRSDRGKKLGVDRLAREYQEFVEKRLPKSALIGLSSCIDIWQEWGSIVSDECHKILVESILSLLEEEDEDKRWMRNSLAHFYVLLIGQAKDDNSLYRLISLVVSGRIDSTCELRSILYFIQVNRHGEESIAALSITHMIESDSEEVLRLGINAAKAHLLVGIGRPGVQETKKILCVLSSHSSPSPLLDLLLDYSTPLFETDKNELNASPLWRQRISYQLVPLFEEAVRESKTREWKITLLSALRHIVKLSANDASFLAPLLDTLISCLVDISINSSSISNESMLFLVESLDQLIERTEEKILTKEKVAGIVHSLCLLVENRKTENKVLFTAIKCIRNLLSTASPITCQPSITRVIRALARASGHSKRTIRTCAADARNRWELLGSV
The following text describes a protein:
Function:
Provides the (R)-glutamate required for cell wall biosynthesis.
Sequence:
MKIGVFDSGVGGFSVLKSLLKAQLFDEIIYYGDSARVPYGTKDPTTIKQFGLEALDFFKPHQIKLLIVACNTASALALEEMQKHSKIPVVGVIEPSILAIKRQVKDKNAPILVLGTKATIQSNAYDNALKQQGYLNVSHLATSLFVPLIEESILEGELLETCMRYYFTPLEILPEVVILGCTHFPLIAQKIEGYFMEHFALSTPPLLIHSGDAIVEYLQQNYALKKNACAFPKVEFHASGDVVWLEKQAKEWLKL
The following text describes a protein:
Function:
Symporter that cotransports short-chain neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane. The transport is elctrogenic, pH dependent and driven by the Na(+) electrochemical gradient. Participates in the astroglia-derived glutamine transport into GABAergic interneurons for neurotransmitter GABA de novo synthesis (By similarity). May also contributes to amino acid transport in placental trophoblasts. Also regulates synaptic plasticity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain.
Sequence:
MMHFKSGLELTELQNMTVPEDDNISNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKKKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFNLCRHTVVTCILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWAALFLGLGVLFSLVSIPLVIYDWACSSSSDEGH
The following text describes a protein:
Function:
Negative regulator of the heat shock (HS) response. Affects negatively HSFA1B DNA-binding capacity in vitro. Involved in acquired thermotolerance but not basal thermotolerance. Crucial for seed development, after fertilization and during embryogenesis.
Subcellular Localization:
Nucleus. Cytoplasm, cytosol. Note=Translocates from the cytosol to the nucleus upon heat shock (HS).
Sequence:
MDGHDSEDTKQSTADMTAFVQNLLQQMQTRFQTMSDSIITKIDDMGGRINELEQSINDLRAEMGVEGTPPPASKSGDEPKTPASSS
The following text describes a protein:
Function:
Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.
Subcellular Localization:
Dynein axonemal particle.
Sequence:
MASKGTEGFGNIACWGFSPAQDLQDLGKELRLEKLTLSESAEPSRDLNVLLVGAGDCRHILKTIAQSYRWNRRKINFYVVENQLELLLRHLLLLNIALEPPDRMGLQEKTELYLEVFGDALVREQTADYIRSKATDFIKLITDADRLARDMPLIDMSMLKFRERDAMEAICKFWRDTEDKSFDIVKFWDARQRRYLEVRYDSRKNVYDWDRTMKLHEKDAKILHGSEYNRWRDSGVAFQVREGDYTVGNRTLASGVLIKREGERIPARGYWGDIATGPFISHGIESENQDLFKTANGLHTGCCSFVSEYNLLAMFHEILHRERYVPPKEQKDAEGKKGATLTEITEEEEEAEDEGTEQTTDTSGGGDRGDGTTKDEDQALIPCPDFKVHFLPLNACSDIPRRSKYAELFDVVFFATGMVHGITPELNTTLADEAVIIVETAKYLIDLRKEQLEQFGSKVNEMAAAAGWKPISTCDFTKDVFAKYQFKRES
The following text describes a protein:
Function:
Mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Domain:
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
Sequence:
MTTAAPTPSLFGQCLAEFLGTALLIFFGTGCVAALKVAGASFGLWEISIIWGVGVSMAIYLSAGVSGAHLNPAVSIALWLFAGFEGRKLPFYITAQVAGAFCAAALVYTLYSSLFIEFEQAQNIVRGSQDSLALASVFSTYPHPALSVGQAFLVEVVITAILMAVIMALTDDGNGLPRGPLAPLLIGLLIAVIGSAMGPLTGFAMNPARDFGPKLMTYLAGWGPIAFTGGREIPYFLVPIFAPILGACLGAGGYRVLIARHLPSAAAPAEAEPEKVRAS
The following text describes a protein:
Function:
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MMKTNPSIFQFAIIFILILEIRIQLSEEIDFLVNRSKAGLFHIPKDLSLKTTILDISQNYISELQTSDILSLSKLRILIVSYNRIQYLDISVFKFNQELEYLDLSHNELGRISCHPTVNLKHLDLSFNAFDDLPICKEFGNMSQLEFLGLSATQLQKSSMLPIASLHIRKVLLVLGDTYGKKEDPESLQKLNTESLHIVFPIRKEFSFTLDVSVSTAVSLELSNIKCVPDGHGWSYFQNVLSKLQKNSRLSSLTLNNIETTWNFFIMLLQLVWHTSIEYFSISNVKLQGYPDFRDFDYSDTSLKALSIHQVVSNAFNLPQSYIYKIFSNMNIQNFTVSGTHMVHMVCPSQISPFLHLDFSNNLLTDIVFKNCRNLIKLETLSLQMNQLKELASIAQMTNEMKSLQQLDISQNSLRCLPPKVKVLDLHDNRIRSIPKPIMKLEDLQELNVASNSLAHFPDCGTFNRLSVLIIDSNSISNPSADFLQSCHNIRSISAGNNPFQCTCELREFVQSLGQVASKVVEGWPDSYKCDSPENYKGTLLKDFHVSPLSCNTTLLLVTIGVAVLVFTVTVTALCIYFDLPWYLRMVFQWTQTRRRARNTPLENLQRTIQFHAFISYSGHDSAWVKSELLPNLEKEELRICLHERNFIPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNNLILILLEPIPQYSIPSSYHKLKNLMAQRTYLEWPKEKSKHGLFWANLRASINIKLREQAKK
The following text describes a protein:
Function:
Dynein-attachment factor required for cilia motility.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm.
Sequence:
MPAPKMMNAENEVEKRIVMMRELLKTMVDVRNLKQSKELRNSIEDEVKRQSVDAAKKRAAAQNVDYPCFANLVSCAHLKPMTRKELDSKIDRNPKHEGSIPAWSFDVTGHSQPGKPILATCRQTKSDTVLNRLASNQDLPSSIGSNLSCFENPLFRAHEQKRLAFHHVSESAVSALPCVPSTGLGWKGNGSRMPTVQKPGPKGSSYSSDLFIKEWKLLNSSQPSERLSYLINFPPSSLPKIFWVEIPPFLLAQILETLRSTALNLRKGTGTDDKSRAGLSLDSDERPTHVHEHMSDCASTATRSHYKKHTTELRKNGSVSDPEEEIVHEQHHVLYPPPHNRVMDGKERVLSWVASVMEALTRCGRFGLAVKLVGQESRDSAREILEHITSATATDEPEMLTSGPRPSELVHKYSCI