lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro). Binds to RNA. May participate in nuclear mRNA metabolism.
Subcellular Localization:
Nucleus.
Sequence:
MSHALHQTRSSGHLRGTQQNLSGSLNLAEPEFWRGSVRWKVPVPDVHLQERLCVLRWLDYTAVGRRLQGTRFIAFKVPLKQALTRMLPRSSVFGPWELLDAVSRDRQELGLIIDLTFTSRYYDLQDLPASLMFVKIFTAGHQVPSDGTILSFKRAVNNFLRDNQDNDKLIGVHCTHGLNRTGYLICRYLIDVDGMDPAEAVKLFNSSRGHAIERQNYLKDLHRGPKRSNEGMEELEQEPMRGQAMSKPTPTPPPTCLAAASYRCFPPNVSPLLLPLRDRPNPGLPPPPLFQPYQWGGTPPQGDWTRPPRPETNRFRPFPPSGPAWSPPYGPPESRRWPAPQPHLQYSPSWAAGEEDWTPPGGRHSSREGWRQNGPKF
The following text describes a protein:
Function:
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the third and last glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(2)Man(9)GlcNAc(2)-PP-Dol to produce Glc(3)Man(9)GlcNAc(2)-PP-Dol.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MLKQFIPLVCLLGYSIVSFAVFNKVYETSQQVIDEEFHLRQGDHYCHGRFQVWDPKITTFPGLYLASALVLRPLDACSVYNLRLTSLIAGIINVVLIYKLRQRFLSQKGYTTLLLETASLSLLPPLYFFSHLYYTDVISVTAVLLLLLASERRHHNWAALFGCCAVLMRQTNIVWVGFVCGSRAIDLLVARGSVSQTLLSPRMLFHTVADILDRLWAYAIVMVGFVAFLAFNGSIVIGDKSAHEAAVHLPQLLYFVVFFMVFSSSLVLPAIRSILRAVLRKWYFTLVVCAIIGAIVHYNTIVHPYLLADNRHYTFYLWNRFFGRWWFARYLPVPLYTVASWLVWKASMQHQSYGYKLLCTLAVLASIALQQLLEVRYFLLPFLVMRLLRKGGTARGALALELVINVAMNIATFALFFHKEIVWKNYAHPQRLMW
The following text describes a protein:
Function:
Phosphatase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process.
Miscellaneous:
MISCELLANEOUS: Present with 22700 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTTAQDNSPKKRQRIINCVTQLPYKIQLGESNDDWKISATTGNSALFSSLEYLQFDSTEYEQHVVGWTGEITRTERNLFTREAKEKPQDLDDDPLYLTKEQINGLTTTLQDHMKSDKEAKTDTTQTAPVTNNVHPVWLLRKNQSRWRNYAEKVIWPTFHYILNPSNEGEQEKNWWYDYVKFNEAYAQKIGEVYRKGDIIWIHDYYLLLLPQLLRMKFNDESIIIGYFHHAPWPSNEYFRCLPRRKQILDGLVGANRICFQNESFSRHFVSSCKRLLDATAKKSKNSSNSDQYQVSVYGGDVLVDSLPIGVNTTQILKDAFTKDIDSKVLSIKQAYQNKKIIIGRDRLDSVRGVVQKLRAFETFLAMYPEWRDQVVLIQVSSPTANRNSPQTIRLEQQVNELVNSINSEYGNLNFSPVQHYYMRIPKDVYLSLLRVADLCLITSVRDGMNTTALEYVTVKSHMSNFLCYGNPLILSEFSGSSNVLKDAIVVNPWDSVAVAKSINMALKLDKEEKSNLESKLWKEVPTIQDWTNKFLSSLKEQASSNDDMERKMTPALNRPVLLENYKQAKRRLFLFDYDGTLTPIVKDPAAAIPSARLYTILQKLCADPHNQIWIISGRDQKFLNKWLGGKLPQLGLSAEHGCFMKDVSCQDWVNLTEKVDMSWQVRVNEVMEEFTTRTPGSFIERKKVALTWHYRRTVPELGEFHAKELKEKLLSFTDDFDLEVMDGKANIEVRPRFVNKGEIVKRLVWHQHGKPQDMLKGISEKLPKDEMPDFVLCLGDDFTDEDMFRQLNTIETCWKEKYPDQKNQWGNYGFYPVTVGSASKKTVAKAHLTDPQQVLETLGLLVGDVSLFQSAGTVDLDSRGHVKNSESSLKSKLASKAYVMKRSASYTGAKV
The following text describes a protein:
Function:
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May be involved in the accumulation of coenzyme A in the mitochondrial matrix (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MTVHGNTKTSPMVTLLAGGVSGVIAKSTIAPLERVKILYQVKSKMYSFNSVYGLMKNIIKNEGLAGLWKGNTATILRIFPYSAIQWTSYDYLKNNFVTDKKSSVQIFIAGSLGFSCAILLTYPLDVIRARLALSYSNNNNNNSINSKNLNSSTQPPKVLKNGIGAVNIEKSIDFNGYKTKGLFKGIWRGILPTLYGSIPYAGVGYSSFEYFKRIAPDSFRNEKGDVIGIYKLISGGVAGGLGQTAAYPLDVVRRRIQTTGYGDGKGVENLKHSTLKTMFTIFQKEGIYALFKGISINYIKVIPTNGVAFLTYETLCDYFNSKLNKN
The following text describes a protein:
Function:
Causes inhibition of cell division. At high levels of expression, can also abolish the rod shape of the cells. Division inhibition by KilR can be relieved by overexpression of the cell division protein FtsZ.
Miscellaneous:
MISCELLANEOUS: This protein is encoded on Rac prophage.
Sequence:
MIAHHFGTDEIPRQCVTPGDYVLHEGRTYIASANNIKKRKLYIRNLTTKTFITDRMIKVFLGRDGLPVKAESW
The following text describes a protein:
Function:
Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
XLPRDWTWAEGMGLGPPELSGSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSGKKAGDWKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLE
The following text describes a protein:
Function:
Mitochondrial GTPase required to maintain proper development, morphology and intracellular distribution of mitochondria, which in turn are essential for the progress of embryonic cell division, development of haploid male and female gametes, and pollen tube growth.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Sequence:
MARYAAGAVDCPGSPKSVRIVVVGDKGTGKSSLIVAAATDSFPPNVPPVLPDYKLPIEFFPDGIPVTIVDTSSRPEDRDIVAEELKRADAVVLTYACDRPETLERLSEYWLPELRRLEVKIPIIVAGCKLDFRDDNNQVSLEQVMSPIMQQFREIETCIECSALKQLQAQEVFYYAQKTVLHPTGPLFDQDSQALKPRCVRALKRIFILCDHDRDGALSEAELNDFQVKCFHAPLQPSEIEGVKRVVQEKLPEGVNERGLTVTGFLFLHALFIEKGRLETTWTVLRKFGYNNDIRLAEELLPSAIFKRAPDQSFELTNAAIDFLKGMYMLFDDDQDNNLRPQEIEDLFSTAPESPWKEAPYEDAAEKTALGGLSFDAFLSMWSLMTLLEPARSVENLIYIGFPGDPSTAIRVTRRRRLDRKKQQCERKVFQCFVFGPNNAGKSALLNCFLGRSYTDNQESTTDERYAVNMVDESGAKKTLIMREIPEDGVQGLFSSKESLAACDIAVFVYDSSDESSWKRATQLLVEVANYGEATGYEVPCLMVSAKDDLDSSPISIQESTRMTQDMGIEPPVSISSKLGDFNNLFRKILTAAQHPHLSIPETEAGKSRKHYNRLINRSLMAVSIGAAAVVVGLAAYRVYATRKSSSA
The following text describes a protein:
Function:
Required for the auxin influx facilitator AUX1 polar trafficking and its asymmetric localization within the plasma membrane. Not involved in the PIN proteins localization.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MAIITEEEEDPKTLNPPKNKPKDSDFTKSESTMKNPKPQSQNPFPFWFYFTVVVSLATIIFISLSLFSSQNDPRSWFLSLPPALRQHYSNGRTIKVQVNSNESPIEVFVAESGSIHTETVVIVHGLGLSSFAFKEMIQSLGSKGIHSVAIDLPGNGFSDKSMVVIGGDREIGFVARVKEVYGLIQEKGVFWAFDQMIETGDLPYEEIIKLQNSKRRSFKAIELGSEETARVLGQVIDTLGLAPVHLVLHDSALGLASNWVSENWQSVRSVTLIDSSISPALPLWVLNVPGIREILLAFSFGFEKLVSFRCSKEMTLSDIDAHRILLKGRNGREAVVASLNKLNHSFDIAQWGNSDGINGIPMQVIWSSEASKEWSDEGQRVAKALPKAKFVTHSGSRWPQESKSGELADYISEFVSLLPKSIRRVAEEPIPEEVQKVLEEAKAGDDHDHHHGHGHAHAGYSDAYGLGEEWTTT
The following text describes a protein:
Function:
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation.
Subcellular Localization:
Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Predominantly located in the principal piece of the sperm tail.
Sequence:
MPKGRAGSLPTTSIGWRFQLWFLGLTCPERHLARRLKNNSFYPFVQQEPNVFVLEYYLDTLWKGMLLFIISVVLVSFSSLREVQKQETWVFLVYGVGVGLWLVISSLPRRRLVLNHTRGVYHFSIQGRTVCQGPLHLVYVRLALSSDAHGRCFFHLVLGGHRLEPLVLVQLSEHYEQMEYLGRYIARKLNINYFDYLATSYRHVVRHWPPPGAGTVMGKSPMGHKPSSSQSSLEV
The following text describes a protein:
Function:
Major starch-binding protein present at the surface of the cell. Mediates starch-binding before starch transport in the periplasm for degradation.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Domain:
The binding pocket contains an arc of aromatic residues that complements the natural helical structure of starch and imposes this conformation on bound maltoheptaose. Binds cyclic oligosaccharides with higher affinity than linear forms.
Sequence:
MKTKYIKQLFSAALIAVLSSGVTSCINDLDISPIDPQTGGSFDQQGVFVKGYAMLGVTGQKGIDGSPDLDGQDEGESGFYRTTFNCNELPTDECLWAWQENQDIPQLTSISWSPSSQRTEWVYVRLGYDITQYNFFLDQTEGMTDAETLRQRAEIRFLRALHYWYFLDLFGKAPFKEHFSNDLPVEKKGTELYTYIQNELNEIEADMYEPRQAPFGRADKAANWLLRARLYLNAGVYTGQTDYAKAEEYASKVIGSAYKLCTNYSELFMADNDENENAMQEIILPIRQDGVKTRNYGGSTYLVCGTRVAGMPRMGTTNGWSCIFARAAMVQKFFSNLEDVPMLPADVEIPTKGLDTDEQIDAFDAEHGIRTEDMIKAAGDDRALLYSGVGGGRRKIQTDAISGFTDGLSIVKWQNYRSDGKPVSHATYPDTDIPLFRLAEAYLTRAEAIFRQGGDATGDINELRKRANCTRKVQTVTEQELIDEWAREFYLEGRRRSDLVRFGMFTTNKYLWDWKGGAMNGTSVASYYNKYPIPVSDINNNRNMSQNEGYK
The following text describes a protein:
Function:
Transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes.
Subcellular Localization:
Nucleus.
Domain:
The DELLA motif is required for its GA-induced degradation.
Sequence:
MKRGHGETWDPAPQSQQPSGSCEGSSSVVDNIKGKMADDSNMDELLEVLGYKVRSSEMAEVAQKLEQLEMVLSNDDVGSTVLNDTVHYNPSDLSNWVETMLSELNNPEPSDLDPTRICEDRSEYGLSAIPGLSAFPKAEEGAEEEASSKRIRLESVGSWGELTRPVVVVDSQETGVRLVHALVACAEAIQQQDLNLADALVKSVGTLAASQAGAMGKVATYFAQGLARRIYAADLSGGSSVGPSFEEALQMHFYESCPYLKFAHFTANQAILEAVTTARRVHVIDLGLNQGMQWPALMQALAVRPGGPPSFRLTGVGPPQTESSDSLQQLGWKLAQFAQAIGVEFEFKGLAAESLSRTGDVRDPARIGNISEANHNGVVFLDRFNEALHYYSSLFDSLEDSYTLPSQDRVMSEVYLGRQIVNVVAAEGTDRVERHETLAQWKARMGSVGFDPVPLGSSAFKQASMLLSVFAGGDGYRVEENDGCLMLGWQTRPLIATSAWKLAGA
The following text describes a protein:
Function:
Initiates a process leading to the deglycation of proteins. Phosphorylates low-molecular-mass and protein-bound erythrulosamines and ribulosamines, but not fructosamines or psicosamines, on the third carbon of the sugar moiety. Protein-bound erythrulosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions.
Sequence:
MAANVALLSASSPSTSASSILRRHPPPRRSACPRRAASRLSVVAAMSDDPIKEWILTEGKATQITGTSSIGGGCINAAQRYDTDAGSFFVKTNRRIGPAMFEGEALGLKAMYDTKSIRVPLPYKVGSLPTGGSFIIMEFIQFGRSRGDQVTLSRNPFRSKKKSALGRKLAEMHKSAKSDKGYGFYVENTIGSTPQINTWTADWIEFYSKHRLGYQLKLISQRFGDSAIYEKGQRLIEKMHLLFDGAVIEPCLLHGDLWSGNISADANGDPVILDPACYYGHNEAEFGMSWCAGFRGDFYSSYFEVMPKQPGFEKRRDLYLLYHYLNHYNLFGSGYRSSAMSIIDDYLRMLKA
The following text describes a protein:
Function:
Operates as a Na(+)/H(+) antiporter that plays a role in regulation of xylem Na(+) concentration and, consequently, Na(+) accumulation in the leaf. Required for pollen tube guidance, but not for normal pollen development. May also be involved in the development or function of the female gametophyte.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MADPAAESIDASSSRFGRVVCYNQTAMHGSNTISAAAPFFMTQLSVANLTYRILYYFLKPLCLPPFVAQILCGLLFSPTVLGNNEVVLKLIFPYKYTMLLETFANLALVYNVFLLGLGLDLRMIKIKDIKPVIIAIVGLLAALLAGAGLYYLPSNGEADKILAGCMYWSIAFGCTNFPDLARILADLKLLRTDMGHTAMCAAVVTDLCTWILFIFGMAIFSKSGVRNEMLPYSLASTIAFVLLCYFVIQPGVAWIFNNTVEGGQVGDTHVWYTLAGVIICSLITEVCGVHSITGAFLFGLSIPHDHIIRKMIEEKLHDFLSGMLMPLFYIICGLRADIGYMNRTVSVGMMAVVTSASVMVKILSTMFCSIFLRIPLRDGLAIGALMNTKGTMALVILNAGRDTKALDVIMYTHLTLAFLVMSMVVQPLLAIAYKPKKKLIFYKNRTIQKHKGESELCVLTCVHVLPNVSGITNLLQLSNPTKKSPLNVFAIHLVELTGRTTASLLIMNDEAKPKANFADRVRAESDQIAEMFTALEVNNDGVMVQTITAVSPYATMDEDICLLAEDKQACFILLPYHKNMTSDGRLNEGNAVHAEINQNVMSHAPCSVGILVDRGMTTVRFESFMFQGETTKKEIAMLFLGGRDDREALAYAWRMVGQEMVQLTVVRFVPSQEALVSAGEAADEYEKDKHVDEESIYEFNFKTMNDPSVTYVEKVVKNGQETITAILELEDNNSYDLYIVGRGYQVETPVTSGLTDWNSTPDLGIIGDTLISSNFTMQASVLVVQQYSSANRQTAENNNQEPVQGKAKTDHEATPFMEDEDDEVEHQYSMRR
The following text describes a protein:
Function:
Transcription factor involved in the negative regulation of flowering time in short days, probably through the photoperiodic and vernalization pathways. Prevents premature flowering, particularly in the cv. Landsberg erecta background. In non-inductive photoperiods (e.g. short days), required for flowering through VIL2-mediated maintenance of the epigenetically repressed state of MAF5 via H3K9me2 and plant homeodomain / polycomb repressive complex 2 (PHD-PRC2)-dependent H3K27me3.
Subcellular Localization:
Nucleus.
Sequence:
MGRRRVEIKRIENKSSRQVTFCKRRNGLMEKARQLSILCGSSVALFIVSSTGKLYNSSSGDSMAKIISRFKIQQADDPETLDLEDKTQDYLSHKELLEIVQRKIEEAKGDNVSIESLISMEEQLKSALSVIRARKTELLMELVKNLQDKEKLLKEKNKVLASEVGKLKKILETGDERAVMSPENSSGHSPPETLPLLK
The following text describes a protein:
Function:
Plays an important role in the regulation of rRNA transcription. Binds near or at the enhancer region of rRNA repeating units. May have DNA polymerase activity, but it is not required for in vivo function.
Miscellaneous:
MISCELLANEOUS: Present with 4490 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTGKVNRDLFFKLASDLREERLHAAVALIKDLSALDLPDDAEEWSYVLNRLIKGLSSDRNSARLGFSLCLTEVINLAVNMPPGQRPKGLESTNEFLSTLSTILNVNVNEGTKKSMKGKDERGILFGKLFGLKSLLNEPLFSEIFVKDLEKGNTEFFIRFTEQLIDLALKKNWIKEPCFFTLFQTMKMLLPFMDESSAEKILLIYDKYDLTLTNEGLSTYLLLKYEGDESLIPSVLDLKNPGWKDNDPLARGNLPLLTKVLRNSSVIPDANGGLKETKKQKNTNWNPRLHFVWSVLLPLFGNGKLENTSHISKKRKKTNNKKVQNSIQFPEFWKMAVDESFFNEKASSERKYLGFLIIDAAFKAVPGSYIGFCFSQNVMRTLINQSIDSQRVLNKISQLTLDSIVKACEEDSANRLVPCLNAMLFGPHGSINFDKLTKSGTVSKLIAIKELPSTVLAQLLDVFFLQLQDKKGVLSHTLFALDSILHIVRAHKVEINDMDIMKPVLRPIVYMAFFKHTSDDLKLEQLHELAKERLYSILGELTINKEIRCKDPEINSWQYLTLKLILDIENSHVGDLINPLDENLENIKNEAISCLSKVCRSRTAQSWGLSTLLSMCLVQLYAGDTDSISVIEELCEFSKHENNSMVGITEILLSLLAQKKALLRKLSLIIWQQFIEEVGLEELQILLDILKARENKQGFAQLFEGEEEFEEIKEENDASEDESKTGSESESESESDSDDADEKDEEDEANEDILNIDKEATSALVKALNLPDNIVNDKGEVDLDQLEGLSDDGGDDEDEESMDDEKMMELDDQLSEIFKRRKEALSSISTGNQRKFEVKQSRENVISFKHRVVDMLAVYVKYCEKLTLANKSEHSNNLGGSLSKLVYFIIPMLKCVNETLDRPLADKISKLLKGKIFKIKVTAFKDMNKDIELMDLLKKTHKLMLTSKPGQHAAVFYSMCSTSSLFLSKLYVEIGGNDKLDELIDLYTATTKEWMQKGKCGPNIFIDFINWLSSKKQTVMDKE
The following text describes a protein:
Function:
Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression.
Miscellaneous:
MISCELLANEOUS: Present with 981 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MRRTFSQLATRLLKSKDDELKSTLKYLTKGPVKLLGPLFESSEVNEQGSLLNRSRTKENNLQNHHIENILRILNSNLPEVESKKQKVAVHYDVLFSHLNSIVTQATDNKSSSSKELQGSSSEDLYDRLLLLQYVGKLTNVRQITEILLSKKFNKFDKVWEHRALFDEYQRVVISILLYYRTHDVQIRKDYEPRWLSDYSDLPFPLRRLLWRCLTSNVSEDNIRQNIIHYIKLLGANWRNNDLILIYQSLYEKSHILPDLTVLNHNKDDGFSFTQNQILLVRILRAISKCVEEEPKLVKKWLIDIVKLSIQSKIMLESPKKPSTPIMDQYKFIRSLDISIRSIHRTCQDKLIFEDLQVNLGSVLKMINEEEHELKTHLPLNLI
The following text describes a protein:
Function:
Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.
Subcellular Localization:
Secreted.
Sequence:
FSPNSPSDVARCLNGALDVGCGTFACLENSTCDTDGMHDI
The following text describes a protein:
Function:
Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
Sequence:
MNRILVTEKIAAEGLAVLRQAGTVDVRLDLDKPTLISIIGEYDALVVRSATKVTAEVIAAGERLRVIGRAGTGVDNIDVEAATRRGIIVVNAPASNNVAVAELTIGLLISLARRIPQAHASLQSGRWARNDFVGWEVRGKTLGLVGLGRIGSEVARRARSLEMEVLAYDPVVSFDRAEQLGVSLVTLDELVQRSDVISLHVPLIESTRNLFDQQRIMQMKRGAYLINASRGGIVDEVALVEALNSGHLGGAALDVYNQEPLPADSPLLGHPKIITVPHIGASTTEAQLSAGTEMAEGVVTALNGGTPRYAVNAPFVAPEAWNVLQPYLNLGRLLGTLVMQLVQEPVRSYDLELGGELADMDTQPVRLAVLQGLLAASSSERITPVNAPIIARERGVRMTERVSPEAENYAGLITLHVQTAERTRTFSGTVLRGEPHIVQMDGYFVDFVPQGSLLITYHHDQPGMIGKVGQLLGAADVNISGMYVGRRAPRERAVMVLTLDEPAPPQVMEQIATIPGIQAAFSVEL
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MRGSRNLLTQRMASSRASGSSGGLKFVGLTVGAVAAGATSVAVYASYDNDFRKTLENSIPGSRNILNYTIGVEEPPAPRLKDLRPLQFSADPKIAPKPFEPKPVAEKIEKVLVQAEKAPEKAKNPYTGPKEPVNPQKKNENLTESLKKHLVDAEKATKAATGAKLETIRAIEHHIQTIREAIEGGKDGDWDAVTIAHLKAKRMAEADGEWEKKARNAVAELVTEANLGAQGEITQLNPLVPVSKATALKLSNELDEMISNVKHVDSERIFVHDYSDRVAESRKKFQLELKAVHPNLNYEEGMKLKKTDLQTILAHAHLRIDQLSQKLICNKLSEEKRVQSIISKKKADLLEKLRLEAKINVIPEVDKKKLDEELARATAEIQKKYDEKLKEVVRTQKQLYDIEHAKDVDEAVQKERNVHSTAVGKALAQLEGIEMALAGHLHMDIENRKSKQMWLATQNLKETVVFGNRASCCMEGRRAPLGDQMKTLLSCGGNTDEFVKTVDSAMAKTSKIRGEYTEEDLNTRFNKVCRIGRRVAYVHDGSGALGHLYSWLKASLTFQLPIGTNDTVTPSAENNFSLLTRAEALWKAGKKGDAVRVLQMTDGATRRVATDFIQDARRHQEALLLSRLLLAHAALTSIRSTY
The following text describes a protein:
Function:
Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion.
Sequence:
RLTEREAKIRRLVDTNIVGIFIYDLDGWIHVANDAFLRIVGYDREDLASGCINWKHLTPQEWLDRDLRELIPHLMKTGFLSPFKKEYIKKDGSRVPIMLTTATFDEAENEGVAFVVDLTGRREAEHRLRESYEMLRELASRRETDREDERKHIARELHDELGQHLTALRMRASTLRMQLENHHPALVDETRSLIALVDQTMQVVRSVITSLRPPVLDMGIAAALEWLAAEFNRNGRTLCHLLMRDENIEMSEDHAIVLFRVVQEALTNVTRHADATEVIITLDRRPNACLLEVLDDGQGFDVQATRSKSFGLAGMEERVLMHGGKIAIISSPRIGTLVKVDLPAHPLHQERRIEAIAV
The following text describes a protein:
Function:
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Miscellaneous:
MISCELLANEOUS: [Isoform 4]: Disease-associated isoform. Isoform 4 splicing pattern is driven by a variation in the exon 6/intron 6 boundary region that alters exon 6 splicing. Exon 6 skipping introduces a frameshift and the translation of a protein lacking the intracellular, the transmembrane and part of the extracellular domain.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Secreted. Note=A secreted form is produced through proteolytic processing; [Isoform 4]: Secreted. Note=Lacks a Golgi-retention motif, is not membrane bound and therefore is secreted.
Domain:
The domain that induces A-SMASE is probably identical to the death domain. The N-SMASE activation domain (NSD) is both necessary and sufficient for activation of N-SMASE; Both the cytoplasmic membrane-proximal region and the C-terminal region containing the death domain are involved in the interaction with TRPC4AP.
Sequence:
MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEALCGPAALPPAPSLLR
The following text describes a protein:
Function:
Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Is essential for chloroplast development and required for the salicylic acid (SA)-mediated disease resistance to biotrophic pathogens.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to a competing donor splice site.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MATGVLPAPVSGIKIPDSKVGFGKSMNLVRICDVRSLRSARRRVSVIRNSNQGSDLAELQPASEGSPLLVPRQKYCESLHKTVRRKTRTVMVGNVALGSEHPIRIQTMTTSDTKDITGTVDEVMRIADKGADIVRITVQGKKEADACFEIKDKLVQLNYNIPLVADIHFAPTVALRVAECFDKIRVNPGNFADRRAQFETIDYTEDEYQKELQHIEQVFTPLVEKCKKYGRAMRIGTNHGSLSDRIMSYYGDSPRGMVESAFEFARICRKLDYHNFVFSMKASNPVIMVQAYRLLVAEMYVHGWDYPLHLGVTEAGEGEDGRMKSAIGIGTLLQDGLGDTIRVSLTEPPEEEIDPCRRLANLGTKAAKLQQGVAPFEEKHRHYFDFQRRTGDLPVQKEGEEVDYRNVLHRDGSVLMSISLDQLKAPELLYRSLATKLVVGMPFKDLATVDSILLRELPPVDDQVARLALKRLIDVSMGVIAPLSEQLTKPLPNAMVLVNLKELSGGAYKLLPEGTRLVVSLRGDEPYEELEILKNIDATMILHDVPFTEDKVSRVHAARRLFEFLSENSVNFPVIHHINFPTGIHRDELVIHAGTYAGGLLVDGLGDGVMLEAPDQDFDFLRNTSFNLLQGCRMRNTKTEYVSCPSCGRTLFDLQEISAEIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGSPGKIDLYVGKTVVKRGIAMTEATDALIGLIKEHGRWVDPPVADE
The following text describes a protein:
Function:
Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
Subcellular Localization:
Cytoplasm.
Sequence:
MAELGFNEHHQKEVINYMRFARSRRALRLKTIDSCFQDLKDSRLVEETFTVDEVSEMLHGLQVVVHGEVETELINTAHTNVLLLRQLFSQAEKFYLKLQTDVSELENRELLEQVAEFEKAEFTSSSKKTNQESNKPKLAPLNEGGVSELLNKEIARLQEENEKLKARLRTIETQATSALDEKSKLEKALKDLQKIQGDEKLVLKTKEITNLEETVAALKTDFQKTLNASTATQKDLEDNLVTTKHDLLKVQEQLAMAEKELEKKFQQTAAYRNMKEILTKKNEQIKEIRKRLSKYEPNE
The following text describes a protein:
Function:
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing, maturation and degradation events. In vitro, is an active and distributive 3'->5' exonuclease requiring a free 3'-OH on the substrate and releasing nucleoside 5'-monophosphates. Required for normal embryo development.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus. Nucleus.
Domain:
The two RNA-binding domains (S1 motif and KH domain) are separated by a conserved linker of five amino acids (KYGKL) and can bind RNA independently. Both domains are also needed for RNA degradation and interaction with RRP41, another exosome subunit.
Sequence:
MVMRKLQLPLSQTQKVRFERAIERLQSLSSSANSDASVIVTDSIPVNHDDAFLKGHGTSEVDGELLATVCGVVERVDKLVYVRTLRARYKPEVGDIVVGRVIEVAQKRWRVELNFNQDGVLMLSSMNMPDGIQRRRTSVDELNMRNIFVEHDVVCAEVRNFQHDGSLQLQARSQKYGKLEKGQLLKVDPYLVKRSKHHFHYVESLGIDLIIGCNGFIWVGEHVEVRDPMAIDDQKDEEMISSSSTGKEQSHIPLETRQTICRIGNAIRVLSNLGFTVTLEVIMETVNLSNSKNIDIHDMLGSEFHVVVAENEAERRRTKRKK
The following text describes a protein:
Function:
May play a protective role in mucosal tissues by preventing exaggerated allergic responses.
Subcellular Localization:
Mitochondrion.
Sequence:
MFPRRPPATLAAWLAGARGGGLLSALANQCRFVTGLRVRRAQQIAQLYGRLYSESSRCALLGRFWRRLRGRPGHASVLMAALSGVFVWDEERIQEEELQRSINEMKRLEEMSNIFQSSGVENYPPEPKSPAGGNEKSKDKEEPWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDAVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNVMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAKATAPSPERKNEGSCGPARIEYA
The following text describes a protein:
Function:
Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
Miscellaneous:
MISCELLANEOUS: Probably exported via the flagellum-specific export pathway.
Subcellular Localization:
Periplasm.
Sequence:
MINNSNDIGFIQDIAGLDKLRQKAVNGDENAGQSALTAAARQFESIFTSMMLKSMRDANSDFKSDLMSSQNEDLYRQMLDEQMASEFSSSGSLGLADMIVAQLSTGQTASEQKGEDGFQEAMRRVEHARKTASERSNEDLVAAVYPLRKTQAVQSTQFDSRHSFVTKLKPYADKAARMLGVDSSLLIAQAALETGWGQKMVKNARGNSNNLFNIKADRSWQGDKVATQTLEYHNNVPVVEKAAFRSYASFDESFNDYVRFLENNPRYTNALDHGGNSERFIHGIHRAGYATDPQYADKVLRVKAQIDQMNLYKSPAGIFRRHSFSSSIFSAYQS