lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
UDP-glycosyltransferase which uses UDP-galactose and malvidin as substrates to catalyze the biosynthesis of malvidin 3-O-galactoside, an anthocyanin conferring purple pigmentation.
Subcellular Localization:
Nucleus.
Sequence:
MATPALVLLPEWGSGHLMSMLESCKRVLLSSSGGKAFSITLLVMRPPTAEATSEVEAHVRREAACGLDIRFHRLPAVEAPTDAVGVEEFIARYIGLHAPHVRDAVAAMACPVAALVLDLFAAPLVDVARGLGVPSYVFMSSTGAMLALMLHLPVLHESVPAVDFDEMEGDVPLPGLPPVPPDSMPCPVADKRSPNYACFVRLGDRFMDATGVIANTADELEPGPLAAVARGRCVPGRPAPPVYPIGPVLSLGGRSPSHECVAWLDAQPPGSVAFLCFGSMGWFDPPQVAEITAALERCGHRFLWVLRGPPSDASGSEHPTDANLDELLPEGFLERTGGKGLVWPTWAPQKEILAHPAVGGFVTHGGWNSVLESLWHGVPMAPWPLYAEQHLNAFQLVADMGVAVPLKVDRKRGNFVVAAELERAVRSLMDADGEQGRRAREKAARMKAVCRKAVEEGGSSHAALQRLAEALHDGAVIPKK
The following text describes a protein:
Function:
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix. Zona pellucida. Cell membrane; Single-pass type I membrane protein.
Domain:
The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
Sequence:
MSTILKYPKMRKFVAVLLFFCCASQEHTLENPENEELKIQCEENKMRITVQREFFRKTNTPFSPELIRLGWNSTCGPERPGTDTEVMVLSAGLQDCGTESRVDGDWLLYSNQLLLFPAILPTATGSVIVRGVTTVIPVECYYERKQKVIGEPLMPTWIPMTSSIRGFGLLRFSLRIMADECASARSSSVFQQGEAVFLEAAVDSALHPPLTLYVDHCAATVQPDPLSELRYSFITKHGCLMDSVLPGSSSRFLPRQRDDRLCFSVQAFRFRKTPVDQMFISCHLKAAPKRSHHSHLDKACFFHRATFSWRATDGNGAVCECCDSDCLSLEGEENRGDSTSLQIGGRFEADRTVGPLHTLERSHWTGRLSVNQ
The following text describes a protein:
Function:
Commits homoserine to the methionine biosynthesis pathway by catalyzing its O-acetylation.
Miscellaneous:
MISCELLANEOUS: Present with 2240 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MSHTLKSKTLQELDIEEIKETNPLLKLVQGQRIVQVPELVLESGVVINNFPIAYKTWGTLNEAGDNVLVICHALTGSADVADWWGPLLGNDLAFDPSRFFIICLNSMGSPYGSFSPLTINEETGVRYGPEFPLCTVRDDVRAHRIVLDSLGVKSIACVIGGSMGGMLSLEWAAMYGKEYVKNMVALATSARHSAWCISWSEAQRQSIYSDPNYLDGYYPVEEQPVAGLSAARMSALLTYRTRNSFENKFSRRSPSIAQQQKAQREETRKPSTVSEHSLQIHNDGYKTKASTAIAGISGQKGQSVVSTASSSDSLNSSTSMTSVSSVTGEVKDIKPAQTYFSAQSYLRYQGTKFINRFDANCYIAITRKLDTHDLARDRVDDITEVLSTIQQPSLIIGIQSDGLFTYSEQEFLAEHIPKSQLEKIESPEGHDAFLLEFKLINKLIVQFLKTNCKAITDAAPRAWGGDVGNDETKTSVFGEAEEVTNW
The following text describes a protein:
Function:
Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The SCF complex plays a crucial role in regulating response to auxin and is essential for growth and development. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, to the complex and brings it into close proximity to the substrate (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The RING-type zinc finger domain is essential for ubiquitin ligase activity. It coordinates an additional third zinc ion.
Sequence:
MASLNSDVIMGESSSISVPSSSSKNSKRFELKKWSAVALWAWDIVVDNCAICRNHIMDLCIECLANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDVCEWEFQKYGH
The following text describes a protein:
Function:
Aldo-keto reductase that significantly contributes to cellular methylglyoxal detoxification by catalyzing the NADPH-dependent conversion of methylglyoxal to acetol. It also exhibits fairly high activity with glyoxal and probably plays a significant role in detoxification of glyoxal in vivo. Shows broad specificity and can use aromatic aldehydes such as 4-nitrobenzaldehyde, 3-nitrobenzaldehyde and benzaldehyde, and phenylglyoxal. Also catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) and could be involved in ketogluconate metabolism. However, the specific activity of the enzyme toward 2,5-diketo-D-gluconate was reported to be almost 400-fold lower than its activity toward methylglyoxal.
Subcellular Localization:
Cytoplasm.
Sequence:
MAIPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAAVGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTKRKNLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD
The following text describes a protein:
Function:
Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length.
Subcellular Localization:
Cytoplasm.
Sequence:
MKQKRPKYMQIIDAAVEVIAENGYHQSQVSKIAKQAGVADGTIYLYFKNKEDILISLFKEKMGQFIERMEEDIKEKATAKEKLALVISKHFSLLAGDHNLAIVTQLELRQSNLELRQKINEILKGYLNILDGILTEGIQSGEIKEGLDVRLARQMIFGTIDETVTTWVMNDQKYDLVALSNSVLELLVSGIHNK
The following text describes a protein:
Function:
DNA-dependent ATPase and 5'-3' DNA helicase. Unwinds D-loops, R-loops, forked DNA and G-quadruplex DNA.
Sequence:
MLTDLEKNAIRDHYQNIGKNLPGFRPRASQREMIAAVANAFSRTLAREEGGEPPKREGESIAVIEGPTGVGKSLAYLLAGGIMAQTRGKRLIVSSATVALQEQLVDRDLPFLVEKSGLELTFALAKGRGRYLCPYKLYRLTQSNAQQNLLGFEAPAVLWDSKPKPEELKLLRDIADEFSARRFNGDRDTWPEKIDDAIWLKVTNDRHGCLKTACPNRPECPFYLARDVLETVDVVVANHDLLLADISMGGGVILPAPENSFYCIDEAHHLPKKALSRFAAEHSWNIAVWTLEKLPQLTGKIAALTDKAELANLADEAAASLLDSLHEWQFHLAEEPSLSLGVSENDRRTNSEPTWLWEDGKIPEGLETTVSNTAIAARSLLKHVIGLNDALSAARREKEQDGALLDRLTSEFGLFIARIEQISAVWDLLSTVPLEGEEPLAKWITRRADDKNDYIFNASPISSASHLANSLWRRAAGAVLTSATLQSLGNFNLMLRQTGLQWLPETTTLALKSPFDFEKQGELYIPPIYASPKDPEAHTAAVIEWLPKLISPTEAIGTLVLFSSRKQMQDVALRLPGDYLPLLLVQGELPKAVLLQKHHRAIEEGKASIIFGLDSFAEGLDLPGTACVQVIIAKLPFAMPDNPIEKTQNRWIEQRGGNPFIEITVPEAGIKLIQAVGRLIRTEQDYGRVTILDNRIKTQRYGQQLLAGLPPFKRIG
The following text describes a protein:
Function:
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Sequence:
MSDAIISYAALILADAGLDITSDNLLSLTKAAGASVDNVWAEIFAKALEGKDVKEVLSGFHAAGASAGAASGAAASGAAAEAAAEEAAEEAAEESDDDMGFGLFD
The following text describes a protein:
Function:
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MVSEWVAPIVITSIWAFIGIICPFFARGPNRGVTQCCLILTAATCWLFWLCCYMTQLNPLIGPKLSMNEIMIMAREWGNEIKDTMAVTV
The following text describes a protein:
Function:
Phosphatase acting preferentially on D-myoinositol 1-phosphate (D-Ins 1-P).
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MGRSLIFSGNMSLRISHLPRSSLPLQNPISGRTVNRTFRYRCTRILSNSFKSTTRLQTKAVLSEVSDQTRYPRIGAKTTGTISPAHLLEVVELAAKTGAEVVMEAVNKPRNITYKGLSDLVTDTDKASEAAILEVVKKNFSDHLILGEEGGIIGDSSSDYLWCIDPLDGTTNFAHGYPSFAVSVGVLYRGNPAAASVVEFVGGPMCWNTRTFSATAGGGALCNGQKIHVSKTDAVERALLITGFGYEHDDAWSTNMELFKEFTDVSRGVRRLGAAAVDMCHVALGIAESYWEYRLKPWDMAAGVLIVEEAGGAVTRMDGGKFSVFDRSVLVSNGVLHPKLLERIAPATENLKSKGIDFSLWFKPEDYHTEL
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MADYDLTQKLIPHLDRHLAIPLLNHLSDIAIYPAEQLARAQYDLAKGTNMVNYVEQFHAQIENAEPTDFARLRDEATAKYQELQEKAQPVTKVIEDPDAVAKLRSGGDKDRNLDLLRSEYQIDIDQINALYHFGQYQYSLGDYGSAGNLLYHFLILSPSYELNISAQWGKLASNILNGEWDAALMQVRDLRETIDNPHGTSLAKPLAQLQARTWLLHWSLFVFFNLGENQGCQGLLDMFLSPAYLNTIQTSCPHLLRYLVAAAIISRRAPKPANVRSRDHVKELTRIVETEEYQYTDPITSFLKDVFADFDLTQAQQRLSVAESVVRSDFFLSGFADEFVENARWLISEVICRLHRRIDIGQLSKTLNLSNEEGEKWIVNLIRDSRMGVEAKIDLKENMLHITRPHATPTATLIETTRGLAFRSQAIQFAMQSSVGEPRERGERGERGNKGGRGRPRTQEVAA
The following text describes a protein:
Function:
May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
Sequence:
MQAELGLRAALALASAARTPRRAGTCSAWRGAGSATPGSTSACWAAARPPPVSPAPYANNSAAARSSGTASTSGRSSTAAAPSAQGRATAAAAAQGAHGSRSTALNSSNSASASASPVGGGRPQAAAPPSSVRSAYIHLPFCKRKCFYCDFPVEAVGRDPTAPKVEARMASYVEALLREVAATRRQGAAPLETVFFGGGTPSLLPPELLARILEALDARFGIAAGAEVSLEADPGTFDLARLREYRRLGVSRLSVGVQAFQQELLTACGRGHDLLEAEAAIEAVRAAGLASWSLDLISGLPGLTPDMWAASLQRAVAAGPDHVSVYDLQVEEGTPFERWQRAGRLRLPADEAAVEMYGKASQVLTAAGFEHYEVSNYAKPGHRCAHNQVYWRGLPYYAFGLGAASYLQGRRFSRPARMQPYLQWVQQLADSEQGRAGEALPGDHLPEESQEELLLDSLMLALRTADGVDLGRLRRRHGAAAVGVVLRALRPHEQVGSAYAVDGAGRRISIAEAAVTSSPILNPKAAAAAVAAAAAAARGEQGSAAAGIGQEEEPEAGPGPAAGSAAALAAARERARPRAEATVEGTAAEGQPEDATGAVRVRLSDPDGFLLSNDVISDVFAAFDLPSSWLSDNEEGAEGGSSSDTQAGVERKPVAA
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase.
Subcellular Localization:
Endomembrane system. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Domain:
The RING-type zinc finger domain is responsible for E3 ligase activity.
Sequence:
MAGEEAAEGSRSRRRMDLNLYLGLPPLPRPPGRLDATLDCPLLIPNSTVPTPDAPRTGEPEESLARAAAYSPSNALSTPEEQPMLDPIVYAWLDGHSTDGEEDTDAPELAPVDDANVSQPLVAASGLEGDGFTPWVERFVQPGSRMEMVNTSTLRQSLRGASAIEEGTPELRFQRVIQISQQHSIVRPGSVNRSQRAASPDADRLVWAIQRTHNSLEAARRQKMDSDKKVGGKGAAKKDGCCECSSSFECNICLDPAKQPVVTPCGHLFCWPCLYQWLHAHSANSECPVCKGEVLEVNVTPIYGRGGEEGDSANLDMPPRPRANRRESLRQQLQMTDTRGIATVVRQLIENQGIVRGLPSPTGIEMTVVPAGRQRARARRQQRQDNNASSSVPATAIMLHMGNVASESSNQIPLPPSNANNTAPVAPAAPQQSSSVEQLSNSSTTAVIVGEPGSSRRARPSESTVTRRTRRRPQ
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MPGPSPGCGTMSGTNIKMEKSEESMGGGGKGWGGGRDRDSSSDGGGGSGENTGLDPQLWHACAGGMVQLPPVGAKVIYFPQGHGEQAATPPEFPRMMGPQGTIGCRVVSVSFLADTETDEVYARIRLQPLEREAAMSIADSTLDADGGPSSPPPEKPASFAKTLTQSDANNGGGFSVPRYCAETIFPPLDYSIDPPVQTVLAKDVHGERWKFRHIYRGTPRRHLLTTGWSTFVNQKKLVAGDAIVFLRTASGELCVGVRRSMRGTGGADSSTWSGGSSTSHHRPNRWEVKGTESFSDFLGNDSAAGGGSVSSAGSAAGPGGPRAGPGGSNSGPGIGIPGPSTTSSFARNRARVTAQSVLEAASLAVQGQPFEVVYYPRASTAEFCVKAQAVKAALDHTWFPGMRFKMAFETEDSSRISWFMGTISAVQPADSLWPKSPWRVLQVTWDEPDLLQGVSRVSPWQVELVSTLPMQLPPFSLPKKKLRAAQPSDMNMQGQGLMGMPITLPSVFGQINPWAHGLTMEEVTAGMQGARHDRVFGLALSEKFRPGKLPGGFFSAAEGYYPDHAGRGGGGEPHLSAFPLQDRASNISSLISSLGSVPPSGDHGSAGALLVPAGSWSGGSANNKSASTQLVLFGQAINTDSNKSQPQHSGGSSCDGPSLQHLKEESSGKRKDSPSESNQNENFERGQKYMSGSLSNGKQSDLIVGEFQKWVPGLDKERGAGEKLAASPEILQSPQGAW
The following text describes a protein:
Function:
Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules. Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore.
Sequence:
MQRPTTPLRRSNSRQSDHEEHYPIVESVLDMAIGEQMAELADGMSALDRNLKDLQVIHTNLNNFNESFSTLIYGLQMNAWCAEFHNGPRSCDFARRKEVEEMEERARRAQMQAERDRMAMQQIQETPTRLPSEPSDGDVTYMRNDNSFIIQPPSSYQSQLPSRIPQSSRASRIRPPNSLRPPRGRGLYLRGGSRGVTGGRGSYTGVGRGSGRPASEGTTRRWL
The following text describes a protein:
Function:
Catalyzes the glutamate:glyoxylate (GGT or GGAT), alanine:glyoxylate (AGT), alanine:2-oxoglutarate (AKT) and glutamate:pyruvate (GPT) aminotransferase reactions in peroxisomes. Required for abscisic acid (ABA)- and stress-mediated responses in an H(2)O(2)-dependent manner. Functions as a photorespiratory aminotransferase that modulates amino acid content during photorespiration (GGAT activity); promotes serine, glycine and citrulline metabolism in response to light.
Subcellular Localization:
Peroxisome.
Sequence:
MALKALDYDTLNENVKKCQYAVRGELYLRASELQKEGKKIIFTNVGNPHALGQKPLTFPRQVVALCQAPFLLDDPNVGMLFPADAIARAKHYLSLTSGGLGAYSDSRGLPGVRKEVAEFIQRRDGYPSDPELIFLTDGASKGVMQILNCVIRGNGDGILVPVPQYPLYSATISLLGGTLVPYYLDESENWGLDVANLRQSVAQARSQGITVRAMVIINPGNPTGQCLSEANIREILKFCYNEKLVLLGDEVYQQNIYQDERPFISSKKVLMEMGSPFSKEVQLVSFHTVSKGYWGECGQRGGYFEMTNLPPRVVEEIYKVASIALSPNVSAQIFMGLMVNPPKPGDISYDQFARESKGILESLRRRARLMTDGFNSCKNVVCNFTEGAMYSFPQIRLPTGALQAAKQAGKVPDVFYCLKLLEATGISTVPGSGFGQKEGVFHLRTTILPAEDEMPEIMDSFKKFNDEFMTQYDNNFGYSKM
The following text describes a protein:
Function:
Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MIGFVYNIVCMIRCRSRDVVEEEDAYVVGSGTYCGGGTAEMVKLAACKLLYFSYRCQFEPLRNGSTTDIGWGCTIRAGQMMLAHALMRYKNGGGASFEDSIVPSLKQATQHLFHDDPSAPFGIHAITNKGVQHGAPCGSWFGPTHVAVVMGALMEDYLRNGGQGPDVLVLRDRQVMEDEVRKILLLSKHVLLLIPVMLGPHHISEGYAKLLKRCLRMESTVGAVGGKEGSAFFFMGYQGGNLIVLDPHYAQSAFTCSDTQGKISGEWYTLPLTSCSTSVLLGFYIHSPDSFSQFTGDIKDANSSLIFPLIEVTTSDCVGHIFNEDDPDVCSLVSFGDEESSGASQPVT
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that can catalyze both the mono- and symmetric (type II) dimethylation of the guanidino nitrogens of arginine residues in target proteins (By similarity). Delays mitotic entry by inhibiting the Cdr1-Wee1 signaling pathway. Cortical nodes sequester Skb1 from its regulatory targets Cdr1 and Wee1. Positively modulates the shk1 kinase function. May be a mediator of hyperosmotic stress response. Involved in the control of cell polarity by regulating the subcellular localization of Orb6 kinase.
Subcellular Localization:
Nucleus. Cell tip. Cell septum. Cytoplasm, cell cortex. Note=Localizes to the cell tips during interphase and to the cell septum during mitosis.
Sequence:
MNSKTPTLGIVCSEGTISLSLEEGFEFVGVPLSGEGLKLRVEALAPSERLQEFLDDEVAYHPEENVHKVVGLSSAWLELDSEDTLIADRSEEVLLKEASYASYCGLSSIILNGPTSPMNVMRYARAVSSALNSTMNLKFLVQLAIESGHEDYFETWKMWDTIRSACGYHPRLKVALELPPACSPPIELVNRWYAEPIEMITMSCMAFVPNPNGYPVLGRKLRAIYALYLRLNPRILLWDNDAPEKIGDSPDYSIYMKHLFDSQPPAPLVEDLADSYKDYLQVPLQPLSYNLENITYEIFERDPVKYAQYEQAIFSALMDRDESSVTRIAVVGAGRGPLVDCALRAAISSSRTVDMIALEKNPNAFSMLLMRNRQDWAGKVTLVFGDMRTWNPDYKIDILVSELLGSMGDNELSPECLDGVQHVLDEETGICIPSSYISYVTPIMSPKLWSEARNMNDPNAFERQYVVLMNSFDFLAADDEFRFQSLWSFHHPNKDSEVYTKNLHNKRFASVRFQASSPGILHGFAGYFEATLYKDISLSIMPATMEAKSPDMFSWFPIYMPIKKPMYVPENSQLEFHMWRLTDGMRVWFEWCANAYLVLRNGSQIKLSSTEVHNISGKAFSCNMY
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Sequence:
MAPTRRMSNGRSPLVNQQSQITAFFSKTSSSPSPSPVLSKQDLNPKPSPSPSPSPSPTTPSPVQAKLRKPLLVIGPSKTTSPSTPVTGSKSYGEEVVNRRVKVYWPLDKSWYVGCVKSFDELTGEHLVQYDDADEETLDLGKEKIEWVEDKGRSLRRLRRGSVFEKGVVPVGEANVEEESGGDDSSDEDWGKGKGREEVEDDSEDVEFEEEEDEEEEVEGPKKGQSKKVDPKKRKAVGEGTMGSGKRRKSSGGAEKNTFKVSSVEPMKNAESRKASDILDNVLPGDALERFGAREAEKLPFLGGERKDAKRRCPGDANYDPRTLYLPPNFLKNLTGGQRQWWEFKSRHMDKVIFFKMGKFYELFEMDAHIGAKELDLQYMKGGQPHCGFPEKNFSINVEKLARKGYRVLVVEQTETPEQLELRRKEKGSKDKVVKREICAVVTKGTLTEGEMLSANPDASYLMAVTESCQFEERSFGVCVVDVATSRIILGQFRDDSECSTLCCLLSELRPVEIIKPANLLSPETERALMRHTRSPLVNELVPISEFWDSKKTVSEIRSVYRCFNDLSVSGSLNEANLSVKGSFVEEDPLGLPDILSKLVNAGESGSLALSALGGTLFYLKQAFMDETLLRFAKFELFPYSGVSDIFHKPYMVLDAAALENLEIFENSRKGDSSGTLYAQLNHCVTAFGKRLLKTWLARPLYHLDSIRERQDAVAGLRGVNLPSALEFRKELSRLPDMERLLARIFASSEANGRNANKVVFYEDAAKKQLQEFISALRGCELMTQACSSLGVILENVESGLLHHLLTPGKGLPDIHSVINHFKEAFDWVEANNSGRIIPHEGVDKEYDSACKTVKEIELRLKKHLKEQQKLLGDASINFVTIGKEAYLLEVPESLRGNIPRDYELRSSKKGFFRYWTPNIKKFLGELSHAESEKESKLRSILQRLISRFCEHHDKWRQLVSSTAELDVLISLAIANDYYEGPTCRPVISGLSNSNEVPCFTAKSLGHPVLRSDSLGKGTFVPNDITIGGSDHACFILLTGPNMGGKSTLLRQVCLAVILAQVGADVPAESFELSPVDRIFVRMGAKDNIMAGQSTFLTELSETASMLTSATCNSLVALDELGRGTSTSDGQAIAESVLEHFVHKVRCRGMFSTHYHRLAVDYKKNSKVSLCHMACQVGKGVGGVEEVTFLYRLRPGACPKSYGVNVARLAGLPNSVLQKAAAKSREIEGIYGRHRKGSDDGCDERLSSQNSEDDVVFFIQSLINGVAKLSYHKSFKDIHASSLSDLQQRARIFLDQN
The following text describes a protein:
Function:
Required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membrane.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MATSEENSALFPIFILTIMALPLVPYTILKLCRAASKKAKIIHCQCAECSRSGKYRKSIFKRIANFSTYSNLTLVLLWIFMFVLVYYIKNISREIQVFEPFSILGLETGASEADIKKAYRRLSILYHPDKNPDPEAHKYFVEFISKAYQALTDPISRENYEKYGHPDGKQGFQMGIALPQFLLNIDGASGGILLLWIVGVCIILPLVIAVIYLSRSSKYTGNYVMRQTLSTYYYFMKPSLAPSKVMDVFIKAAEYVEMPVRRTDNDPLQKIFGLVRSELNLDLKNIKQEQAKFWKQHPALVKTQLLIQAQLTREFANLPPPLNADFKHVLELAPRLLEELMKMALIPRNVQGQGWLRPATGVIELTQCVIQAVPLSSRKATGGSSEGIAPFLQLPHFSEAVVKKIARKKVRAFEDLQKLGQEERADLLAQVGGFSPAEVQDVETVLEMMPSVTVTISCETEGEEGIQEGDTVTIQAWVTLERRNGLVGALPHAPYYPFHKEENFWFLLADPNSNNVWFYQKVSFMDEATAITAASKAIEEQMEGSGASVRETSAAVREAVEKVKAGSRLVLGKFHAPAEGNYNLTCYCLCDSWIGCDNKTNLKLKILKRTRAGTRGSLMTEEGPSMEDGIEEEEENDEEEYDDYESEYSEDEADEQDVKKKGPVANGKAHKQSSSSEGSGSDDDE
The following text describes a protein:
Function:
ATP-binding RNA helicase involved in ribosome assembly.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MRVQQSKPSAAAKRKAAATSLTTSPQKKRANTTPKRAKDDDFIMTLDSDDDVEDLDAAHVDADHVASDNSEREPEPEAELEPEHSSTPPDGKLTKNQRKRKEKAHLVGKEKIIESLASRSKTNSAAAVKDAMALDKDFEFDIFGDGSAVDYTGAEANGWDMSVTGTRMHKKLNVDDIIEKRRKVLPTLPAPVEEEEENSDEDDQDDDLDDDIKYAEYQDSDDDEDRFGGGNGNIVGQNKDEDQQDAAELDSQEDPLSSDAESASDDDDDNDNDDDDDELQVAEQDEESNSSEDDSDLETEQEKARKAAFFAEDPIATSADSSSKSKSTNDAESSFGAFDLSRPVLRALSSLSFHKPTPIQSRTIPIALAGKDIVAGAVTGSGKTAAFMIPTIERLTWRAKTRTPHEAKSRVLILAPTRELAIQCYSVGKSIAKFTDIRFCLCVGGLSVKSQEAELKLRPEVVIATPGRLIDHVRNSASFTLDDIEILVMDEADRMLEDGFADELNEIVKSCPKGARQTMLFSATMTDDVEQLVRLSLKRPVRLFVDPKRTTAKKLIQEFVRVRGTGTGGVAGADGLSGIQDQPATWISGGRKSEDAQRPALLLSLCTRTFTSQTMIFVRSKKLAHQLKIVFGLLGLSAGELHGDLSQEQRIDALTDFRDGKTDFLLATDLASRGLDIKGVQTVINYDMPGQFEAYLHRVGRTARAGRNGRAVTLVGEADRRMLKLAIKKSSAEQIKHRIIPSAVAAHMCETLERLKPEVDAVLREEKEEKALRIAEMELKKGENMANHADEIFSRPKRTWFQSGSEKTQASALSKAGYQATMDARSSSKQKDKYAGLSRKKRRSKMMRQEIERERKDASGSAGAKTASGGGMDAGIRAAKKAQRPTKLGVAPLKLANKSKGKQSGRNARPSATGGSKTKSSFNRDFSGNKRR
The following text describes a protein:
Function:
Required for the transport of riboflavin to the developing oocyte.
Miscellaneous:
MISCELLANEOUS: On the 2D-gel the determined MW is: 47 kDa.
Sequence:
MLRFAVTLFAVITSSTCKKYSCLEGETHKLKPSPEPNMQECTLYSESSCCYANFTEQLAHSPVIKINNSYWNRCGQLSKSCEDFTKKIECFYRCSPHAAHWIHPNYTAGIQSVPLCQSFCDDWYEACKDDSACVRNWLMDWEWDESGVNHCKNECIPYSEMYVNGTDMCQSMWGESFKVSESSCLCLQMNKKDMMAIKYLLSESSEESSSVSSSEERACQKKLLKFEKLKEEEGGETR
The following text describes a protein:
Function:
Component of the elongator complex, a multiprotein complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSFKRKAAPQIAPTNLPTGVRLSSKDARWITSSGSSSFDYYLSGGIPMKSLLVIEEDSMDYASVLLKFFAAEGLKQDHVIWLGPSIGEMWFRQLPGDSDRPNKNENSAGEDNHSSPPSKNPQQERMKIAWRYEQVSKTKAPTLDMIPPGYTHSFDLSKNLIVKSDMKYAVSPFPLETGSNPYAPVIESLTRFLSTLTPGTVCRLVLPSILSPAFYSIRATHPQHFIRFIHTLSSLIKCTTSVHLICMCSVPSTLFSRDCEQIFWLENLASAVFSLHPFPVKETVNGLVTQPLGLFRIHKLPLALPFTNHANSNEAGDLSFTVSKRRFTIEPWVLPPLDDEQKDTKISNTNPQKQPVKSLDF
The following text describes a protein:
Function:
Binds to the 23S rRNA.
Sequence:
MIKLECLQDPSPRKRRTKLLGRGPSSGHGKTSGRGHKGDGSRSGYKRRFGYEGGGVPLYRRVPTRGFSHTRFDKCVEEITTQRLNEIFDNGAEVSLEALKERKVIHRETSRVKVILKGALDKKLVWKDAAIVLSEGVKSLIEAV
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MATNAESQASDVIKGIYCFQMLQGKTFIQPKREILSMMDMAKWLQSSAYAELLGFIQSLNMAIRNKKISDDFPKSEATKQMLQILDTLDQWTEEIKPIDQPQRFGNAAFRDWRNRLCEKADDLITPLLPDDAKESIIELKAYWKESFGNATRIDYGSGHELSFVAFLFCLCKLEVFHESDCCSLVLQVFNRYLDVVRNLQSRYRMEPAGSHGVWGLDDFQFLSYLWGSSQLIDHPTILPKSFVDPKICQENAHEYMFLDCINFINKMKTGPFAEHSNQLWGISGVLYWAKVNSGLIKMFKAEVVGKFPVVQHFVFGSLLSIAKHEVPRRV
The following text describes a protein:
Function:
Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MEQSVSARWLKRYRAFFLILLLIVAIQLFLAYKSLDIVGGGSGSGFDAAEAPASPPPPHAQARVQPPARTKLTAQQLGFQPECDILAREAISALQRAKTKDCREHIAQIACAIQAGRFYAPQLRSSCPAGNHTANVSLGCFKDEKDRRLLAGYYSSSKTSNSPAKCVELCLQSGYPYAGVQYGRECFCGYDPPPKASKLPDSSCNTKCLGNAKEICGGFYAMNIYETGIAKFTAQLAATTPSEETKRVRIAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDERQDYLYRKLLELESKFPNIRLARKRFSTIWGGASLLTMLLQCMEDLLQSNWHWDFVINLSESDFPVKTLDKLVDFLSANPGRNFVKGHGRETQKFIQKQGLDKTFVECDTHMWRIGDRKLPAGIQVDGGSDWVALSRPFVGYVTHPREDDELLQALLKLFRHTLLPAESFFHTVLRNTKHCTSYVDNNLHVTNWKRKQGCKCQYKHVVDWCGCSPNDFKPEDWPRLQATEQKSLFFARKFEPVINQAVLLQLEEWLYGPYTSEYANLHGYWQSLYHHEDVHGSGDDLARSIGDSVMRLSARQAKLYPLELIELTHYLHRDQYKGFLVRYRARGSTGKPLHLETRVRPTQQGKLARNARFSKRLRNFEVSTDFDQKEQIARNFGKLLGPQSDLLLSYTLQANADSGAASHSYNLTLLWIDPLGRLQDFNELHVEDSTSDVINHSKTLLKHPITPGIWTAKLIGRNSIYAQLKFLIAPLAYYKGYPLAKSSDAEALNAGLTVALPEDFEMPVEWQQHLQTDDEQFTMREESLAKGKMLGQELHSWIDGLVGQFFQLRESCVVEADSEVSLPLCSDAPWSSLAPDPKSDVDALLK
The following text describes a protein:
Function:
Voltage-gated chloride channel. Chloride channels may have several functions including the regulation of cell volume, membrane potential stabilization and signal transduction (By similarity).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTRKENEESESLSSSSSPIDNSNNNNNNNNHSIFNPIGHIQNAFNNIDLNPLNVDFKGHTDKVVNFFQHGTGDLNDRMQGVVSKLRSNEYRKKMHSVLTKIKDTKEYKSTSNTDYDVIFESVDMYSNLQQDPTMDKDEIDVVTDLSSYKKKFTHWLGKERISTLLFIPTLGILIALMGILCDFLLMELGTLRDFVTSRHNSHVIPTDGTTPTPNSSIADKYDLVEGIVFVGYSVFFALISVCCISFISPYAVGSGIPEMKSIMSGINLSRVLGFKTLVSKIVGMVCASAAGLTIGRTGPFMHASAIISQMLMNLKVFGAIKKNQIVRYQMLICALTSGVVANFGAPIGGLLFAIEVTATTAVMGNLWKGFLCATTTAIIFFLSRSTFSKGNFHSVYEFEFVPKEYGVADLITFVGIGIITGLIGAFFVFIYEKLVRFRLRYPILKQSRIILVLVVSLFSAIITYSAGPLCRVSLPTAMKQFLGQNEPKPFLFEQDQTPYYKYLNLLVFIVVKLILTAFNIVLPIPGGAITPFIVTGAALGRLFGEILKDHFDSQAIEPAGFAAIASAGLVSGTIRNISPSIFVLELTGQLSLLVPILICSITSTAVGNFFNRPLFDTALKIQGLPFLSNYRSSKVYTMTAKQVMKKNINYLSMTSTVIEMKNFLDTFKYTFIPIVDSKENMLLVGIVERSSMIYMLDIHIENIEQKIDEFKSKYFVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNSENLEIENTGAILNTNSNNNNSDEEDYDRKDNDKISLIKPNQDESSSNSNGGSSSDFEEILNTQNTNINKNDNEDLIKEIEDENSSLGEKPIIEHDDEDDDEEEGDGIPLVSMKDQQPVLRNRHTTTTTTTTTTTPITENIYVNDAFEISINDLKNGGQSVWGKHILGDIIHSGETALLMDLAPSQVPDLTPLNKVFHLFTMLGLGFTYVTSLGKLVGVITKNSLMEQDL