lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the SSU processome, a pre-ribosomal particle required for the maturation of the 18S rRNA from the 35S pre-rRNA precursor.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAEKVQYYMEQSVPELEDLLEKNIFNRDEINNIIKTRRVFEEKLARRQVKLNDFLSYIQYEINLETLRAKRHKRLNITGKITISDYAGPRKVLFLFLRATNKFFGDVTLWLDYIHYAQKIKAVNIVGKICVAALQKHPNNAELWVVACDHEFSINANVSAARALMNRALRLNQENPVIWAAYFRLELSYMTKLFARSQILTGNISSKTENITNGVSEDTIGSLSSDTIQLPMVSMEEFLGSSSSEVRKNDSDLNISDDIGNISSKEQQTQKFANVLLQIILNSRKNLSLQNYVGFFVSVLDALFECFDVPVVQYMYQENIIGICNEHFEHFKNESGEIYGVLLHRWCFLEIFIKLRGAYPSNDSGISGKGIFGLKKNDPRITSMVLTDPGFVDDLQAIVEKYQSISSDFQIPFKTKKIFYSFFVKTLHAISSSSAAESSIALALHMLVINAFQSMEKLKILTFDDSLQEIYKEAQIQSGTFMSNATLS
The following text describes a protein:
Function:
Potential negative modulator of chondrocyte differentiation. Inhibits collagen fibrillogenesis in vitro. May influence chondrocyte's differentiation by acting on its cellular collagenous microenvironment.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MRPTVGCLLLSLMMSVGQTLKCPRVCVCDNTKLTVKCIGNNLTHIPPTIDEIIVKLDLKKNNFGELPKNAFKHTPYLTQLSLQGCSVQAVREGAFRGLSRLLQLDLTNNNIDILYQESFDGLSSLKQLYLDRNRIEEIHPGAFAALNSLNLLSLTYNQLVYLPNMAFQGMMNIQMLHLSHNSLNNLATEAFAGLLALTHLNLDHNELQYFPTKTMTRLIEVTHLDMSYNPMTYLVEESVVMPKLTHLSLKHNALQDLSESTISLSPVISHLDLSFNQLSYIQALAASTHLTSLNLTGNPIRCTCLLRDLKLWALKSGIRLFGVCAWPPHLSDEPLENVQEQDLRCRPQDEWTSDVIEEGTKEEEEGVQEKTVSTAKSKKTRKCPKDCLCEYAAQHATCENRGHTKVPSGFPRKTLLLDMRGNHFHYLPSKSFPGIPEVVSLHLDSCKIHEIEGGAFQGMKNLIYLYLSDNQLSSLDAKVFEGAHEIMYLHLEDNKLTHFPSSATLTHIPKLLELHLERNLIAKLEPSGLLSPVLQLTGLYLNNNSIATIVPKALDPAPKLDVLHLEDNVLTDVPSDALDHAPLLTELHLSGNLIRWIGPRAFRVVAESLKNLLIDRMGLQKMSVRSLAGFGPRLLSLSLEDNLLEELPDLSPLAGLQNLSLNKNPLMCDCKLLPFYRWLEKMSLRVEAVCFYPSELRGQSVMESAIYKNCSIENAHSFNETSIPTKAHEPNIPNPTQPTEPSYAKLKLAKTKIAATPKKTKSKEFKPERALKMTRPNKKKRRRPKMKLPMI
The following text describes a protein:
Function:
Fatty acid elongase with strict substrate specificity for monounsaturated fatty acids, in particular 16:1 (delta-9) to produce the unusual 18:1 (delta-11) fatty acid.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MEHIHDINFQEFSKDPIGTIDRFRWKNEVTPFSNILFPIVCSFGYLALIYGLQIFMKNKKEIKLHGFAMFHNLFLCLLSLLMFLGIVIPMAKYSFPHGLYNIICKPIDSGLVQFSYYIFYLSKVYEFIDTIIQVLRKKSLLFLHVWHHFITLWLVWANLKYDTGCQWVDISANCFVHIVMYFYYFQTERGINPWWKKHITTCQIIQFIVDMSSHLAWHFYDTQGNHNSNYCSGTWATSAFSDFVILSFLGLFIQFFVKAYKKKSSIKKKTN
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.
Sequence:
MDSLSASEQRELQTRMEKKQMKEFMNMYSNLVQQCFDSCVNGFESKSLTSREEGCVMRCVDKHMKGSQRLGDRFQEQNAAMAQQGGLPGR
The following text describes a protein:
Function:
Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.
Subcellular Localization:
Basolateral cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MVVMIQMMLVLFRLQMAGASLPETELDDVCFQVELGFSTFLRSISSNSTVVNIKQTQITVIDQSIFTGLWHLEKLTILDNDKLLSICPSAFANLPRLFDVSISQNMALKKIGAFAFSNLPALTEIEITKSRHLTSIHPDAFRSLVGLRRLIITNTGLRIFPDLSKIHSAVHRFMFDLQDNIHIQAIPANAFRGLCTQTVEEIRLTRNGIREVASDAFNGTKMHRLSLKGNKQLTHISGDAFVGSSELVVLDISETAISSLPDNIISGLKKLLAESAYHLKILPPPQQFAKLRLAKLTYPSHCCAFKNKPRSRSKWSPLCSHPMAKYITDFYRDHCSNSTSITCSPTPDNLNPCEDIMSPVPLRVLIWIISVLALLGNTVVLVVLLGSRSKLTVPRFLMCHLAFADLCMGIYLIIIATIDMLTHGHYYNYAIDWQTGLGCSAAGFFTVFASELSVFTLTAITVERWHTITHALRLDRKLRMRHACVIMAAGWIFSSLAALLPTVGVSSYSKVSVCLPMDVESLVSQVYLVSLLLLNILAFFCVCGCYLSIYLTYRKPSSAPAHADTRVAQRMAILIFTDFLGMAPVSFFAISAALKLPLITVSDSKLLLVLFYPINSCSNPFLYAFFTRTFRRDFFLLAARFGLFKTRAQIYRTETSSCQQPTWTSPKSSRVMYSLANTLSLDGKQEC
The following text describes a protein:
Function:
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates MON1, inhibiting the guanine nucleotide exchange factor activity of the MON1-CCZ1 complex, possibly by preventing its recruitment to membranes by small GTPase RAB5 homologs.
Miscellaneous:
MISCELLANEOUS: Present with 1320 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side. Nucleus membrane; Lipid-anchor; Cytoplasmic side. Vacuole membrane; Lipid-anchor; Cytoplasmic side. Note=Targeting to the vacuolar membrane may depend on AP-3 pathway.
Domain:
The YXXZ (Tyr-Xaa-Xaa-Zaa, where Zaa is a hydrophobic residue) motif mediates the targeting to the lysosomal compartments.
Sequence:
MSQRSSQHIVGIHYAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYLISLMDDALRLNDLKDDGHYDWMDLNGGKGWNIKINRRANLHGYGNPNPRVNGNTARNNVNTNSKTRNTTPVATPKQQAQNSYNKDNSKSRISSNPQSFTKQQHVLKKIEPNSKYIPETHSNLQRPIKSQSQTYDSISHTQNSPFVPYSSSKANPKRSNNEHNLPNHYTNLANKNINYQSQRNYEQENDAYSDDENDTFCSKIYKYCCCCFCCC
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MSSTRSPSPSGTERSSATDTSSDATSIVESISNLHTDDDTIVREQTIQDVLNGSRILVTGAAGFVGAALLHRLLTDQSFNVKQIVAIVRAKTPQDALKRLPKAVHHHAEPECNGALAKLVVVNGDCARPNFGLDEKEFEKVRKTEIVIHCAGDTRFTLPISKAFEAMADLAYFTARFSLLTWNVKTHIHVSTTFVGWYLNNGSLVSETLTPQGCGTRVDEQSEHVNTYFQAKTYAESCVNSLFTSQVGRKLHGKACRIVRLATLGPAIDFPRPAWGAGHPSSPVCAALAAQVVDPSLVFPNAGLDVIPVDIAVNQILAITASAHALQKLPTTHRLHPKNPAAITSKHLAEVPCYHVACGRGDQARIPMTLLNAENVKIEEPYIPTANLLKVYDPFITKIVEFDVARTRTVLGLGALVADQERKINKATIADLPLKHASLQLDIIKSIQERFGHQDLEGWTGYLQQVRDQMEAMGPRSDWETFVD
The following text describes a protein:
Function:
Required for embryogenesis and germline development in both adult hermaphrodites and males. SR-protein kinase (SRPK) that binds directly to and phosphorylates the RS domain of rsp-3/CeSF2 in vitro.
Sequence:
MFVVLFCRWLNGFSQHRERLYKFEDEAVQRRRRFRVHSEESEELNDHESYSETDICTQLLASSADVTCHINVDLVNQNRFYFFVKQRNKKENSTNEEEEISSQEINTSTQNEETEVNLVFASAEDNGGVASNFDISDALMVTSNISEVSKLPETLCEEGETVQQKSVVNENDHSNEDDEQSLQSQDGSRCSDEDMNSCVSASDEEDVESQDDSFHVNDATEESIDSVSSIESQEAEESATEDLASCHSNDDKNEKDVLVDEDTSKYDNLPVEMRSAKEGEESEGTIDSSVSSSTSSSSTGDDGDDSATSYDSEDIEIQMFEYDLGTACASASISIPRPSIIPRNNKKTEVNANEERLDDLSVSPGRSDSPGGGGGGHSDSFQDPMDPGEQLGSDDEEQEDPRDYKRGGYHPVNIGDVFNARYHVIRKLGWGHFSTVWLAWDTQDKRFVAMKIVKSAEHYTEAALDEIKLLLSVRSADPNDIGCHKVVQLLDEFTVTGINGQHVAMVFEVLGCNLLKLIIRSNYRGLHLEQVRKICRQVLEALGYMHEKCGIIHTDIKPENVLITMSREEIKIMAQHAVVARKMNMKMSGSAVSTAPDHLVKMAQENMTKNKKKKMKKKAKKQREKLEAELAGLEGLKMDANGLQEAYNNAPELENFNASQVEDVTMEDTVNENGNRNKVEIRSPDRFDRTTLTPFSDPESKFGDLASPSAEYLSSPMSQLPPGGILPAPPVGPNIGDPYCDIDVKIADLGNACWVNHHYTDDIQTRQYRALEVLIGSGYGPPADIWSTACMAFELATGDYLFEPHQGDNYSRDEDHLAHISELLGAIPPSIYKKGKHWREFFHKNGHLLHIHQLKPWSLYEVLRQKYEWSHEDAQQFESFLRPMLDFDQEKRSTAKIALKHPFLLPFGGRAPKSDCPPELLSKMFPDGLIPEPFDGNEHQEVYRDENDSRSASERSANSRSAGGSDDDDEEEFNMNRPGPSGVITNNETTDISDIERFQLDLQ
The following text describes a protein:
Function:
Acts as a negative regulator of the NEDD8 pathway. Has a role in meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MEIDQNLFQFPISTRDAVHEKNCTLRVKSTKKRRSSTKDEETRGMHPHIKSSFRNGMNHARVIREEDMEVVFEPCFINLSKPVYVVNGIGGINEIHKLPILFSSFVLCFFGNVSGDYGYVDNVPLHISVISHFYPCLQSYNTDVIGITTDTVENICQWKAHLPRALQFSLPVISDSNNEICREMGMLHPLGGAKLALDAIVIIDSIGRRRDILPIRTTTCVSTLITAVQETVRFLAIENGRLL
The following text describes a protein:
Function:
Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells (By similarity). Confers early temporal competence to retinal progenitor cells (RPCs). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (By similarity).
Subcellular Localization:
Nucleus. Note=In resting lymphocytes, distributed diffusely throughout the nucleus. Localizes to pericentromeric heterochromatin in proliferating cells. This localization requires DNA binding which is regulated by phosphorylation / dephosphorylation events; [Isoform V]: Nucleus. Note=In resting lymphocytes, distributed diffusely throughout the nucleus. Localizes to pericentromeric heterochromatin in proliferating cells. This localization requires DNA binding which is regulated by phosphorylation / dephosphorylation events; [Isoform I]: Cytoplasm.
Domain:
The N-terminal zinc-fingers 2 and 3 are required for DNA binding as well as for targeting IKFZ1 to pericentromeric heterochromatin; The C-terminal zinc-finger domain is required for dimerization.
Sequence:
MDVDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSDRGMGSNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIVCIGPNVLMVHKRSHTERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGVCPVIKEETNHNEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSANYEKEDMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPSDGPPRSNHSAQDAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHINPHARNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLS
The following text describes a protein:
Function:
May play a role in the development and maintenance of the nervous system (By similarity). Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane; Single-pass type I membrane protein.
Sequence:
MGFRLITQLKGMSVLLVLFPTLLLVMLTGAQRACPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSVSQGLTWTWSSLHTLDLSGNDIQAIEPGTFKCLPNLQKLNLDSNKLTNVSQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKHIQGEKVSDAVETYNICSDVQVVNTERSHLAPQTPQKPPFFPKPTIFKSDAIPATLEAVSPSPGFQIPGTDHEYEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPASMKQLQQHSLMKRRRKKARESERQMNSPLQEYYVDYKPTNSETMDISVNGSGPCTYTISGSRECEMPHHVKPLPYYSYDQPVIGYCQAHQPLHINKAYEAVSIEQDDSPSLELGRDHSFIATIARSAAPAIYLERITN
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MTPEYGIKLAVHLISTDFGDHAAKVCDCLLRKGTLALDDIVRTAKLSPQQVKTYLKVLIQHNCVQAFAMEHEGGCGEGPVVVTQYMLLFDNILHRMRFPKLLAIVSKELDKECEELFEAFLKHGWLTLQQILDRVPSNQNEGNCTVQDALRGSFTKLVNAHYVERCPAPDPFLVPPDEEKTPARKHDANSAKAVEELEIGEQCDIAKATPSKAKGFPVITDTCGDINGDKSIGNPPGVVIGKKRKQDALKLDTESGAASEKDVPWRANYKELVCHLRHKACIENVRARLDSGAAIVLSAMLEATQSAEKNVKEEISVLLSISTITEAVMQSEAGCSMTLERIRASLVQLGCHPNGVGADRTYNIDLKKIIELAQNDEVESMVLKRYGREAHRIFRLLSKSCCPLETTKISDTTFIEKKEAAKILYKLWKDECLHMEKIVLNESRQSQFMLWKVKKDTFWRHILDEMYHAALNLSIQIIELRRDKHVGALRERDVRLAILLQASLMKLDDALMLFHDF
The following text describes a protein:
Function:
Involved in developmental cell fate decision.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MKNDHINYQQNLSQSPILNSNKNQTQQNQQQQQQQQQQNPQQQQQFQHQQVPQLSPQQIPFSEPLKNNLTLQHQQQQQQHQQLAGGQHGSLLRKSYSSRFHEKPQGELTKIANFQDVSPEERPSLFLLKLKQCCYVYDFSDNTYMVSKGVKQEALLQCVNFLSTNDQPLHESIYKMVFEMVAVNLFRPLPPRINPYGVMYDPEEDEPILEAAWPHIQVVYEVLLRFIDSPTFNTHIAKNYVDDRFVLQMLDLFDSEDPRERDYLKTTLHRIYGKFLGLRGFIRTAIRNLFCTFVYESHQHNGISEILEVLGSIINGFLVPLKDEHKQFLIKVLIPLHKPKSYSVYCSHLGYCMSQFIEKEPSLAEPIFKSILRLWPCGNSQKEVLFLSEMEDLLGLVSDEQFAKFRNQFFRQMTKCFQSEHFQVAERALYLFSNENIVLLIASKNNFTLALETFYKPLHENSISHWNRSIRNLSISSLKLFMEIDMDLFNKISEKYKESKKKQQQIQQREKFKQNAPETQKSKQINQNNNNNNNNINNNNNNNNNNNGSTETKADKPSMIRRKSLLPVDPSTIAALSSHRSLEDIMSTNSNSGNDDDDENNHTNHDSEIENEVKEDFRVPVNNRYTFT
The following text describes a protein:
Function:
Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Acts early in neural plate development to induce expression of some but not all proneural genes, and specify a neural precursor state. Also up-regulates repressors that prevent neuronal differentiation. Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes. Probably dispensable for pronephric kidney development.
Subcellular Localization:
Nucleus.
Sequence:
MSYPQGYLYQPPGSLALYSCPAYGASALAAPRSEELARSSSGSAFSPYPGSAAFTAQAATGFSSPLQYSSDPAGFPSYMGSPYDAHTTGMTGALSYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDDDEGDGERVKEEQSEKAQDCNETSAEDEGISLHVDSLTDHSCSADSDGEKLPCRATDHLCESGSESKEKYDDDEDEEEGDEEDRVLPVKPATSSPLTGVEAPILNHQQDGSPRNSNKTSLDNGMSPSSQTPASKPKLWSLAEIATSDHKHSNLGSVLSSATSSAAHNPSYPSSSLLGRHIYYTSPFYSNYTNYGNFNALQSQGILRYSSAAVTANEGLNQTVLSTSSMHKHTSDSVRTASNQLDQHYRPTNFESKKDPSEVCTVGVQPYP
The following text describes a protein:
Function:
Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria. Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methyl group per binding event.
Subcellular Localization:
Mitochondrion.
Sequence:
MAALRRMLHLPRLTMGTCRPFAGSLADSCLADRCLWDRLHAQPRLGTVPTFDWFFGYEEVQGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADARNLGAVASSGSFQLLLDKGTWDAVAQGGLPRAYQLLSECLRVLNPQGTLIQFSDEDPDVRLPCLEQGSRGWTVTVQELGPFRGITYFAYLIQGSH
The following text describes a protein:
Function:
Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLESASSISDHHVAVIATTVVSLKAANLTYMPSSTCSARSLNCGCSSASCCTVATYDKDNQAQTQAIAAGTSTNIGTSTVCPANQMVNNNENLGSLSPSGGVGSPMLGTPKPLASIKIIYPNDLAKKMTKCSKSHQQSQGPVIIDCRPFMEYNKSHIQGAVHINCSDKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENTNEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDSSLQLQECPEGVGGASAASSVLPQSLPPTTPDIENAELTPILPCLFLGNEHDAQDLDTMQRLNIGYIINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLIGVETVV
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Sequence:
MGVPFEALIPYGIIIAMFGVTGAGLTAAKYFGNEGKKARWNKDLWDRQMMERDLRITGTLRGQSGNAVAPKGFDVSNPWKLVFACIS
The following text describes a protein:
Function:
Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity. Recognizes and binds poly-ADP-ribose chains: specifically binds auto-poly-ADP-ribosylated PARP1, limiting its activity.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MPDIKLSKVISVSSEDKNYPAENILKCGEFKKWKCLAGETKATIVIQLSQASVIDQIHIGNEGSAFVEVLVGRSSLNIDAFQVILMASSFMTPLESRNVQNVNKVRLFKKEHLSQTAANEKWDLVKIVCSQPFNKIDLGSFKLKSQSELSLSRLGVGSLFESSKMNKQSATAASSPSSTSSAMSVAATLRNASTTLQTSGKVVGSPSGGNSGGGVIGSDNSSSSCGKSGSSSSRGSGSAVERIDKDNNPKLKRTFNQHIGMNYDDDDDDDDGGDYDIPKKKFKNDHDLPFKDKQDDREEISSKGRNSNVNNNNNNFYHNNNNNFNHNNNNNKNNNDKNDKKNKSDSSNRRMENTNNNFNNNNKLNSNSTNINKNFINLTSNNINNNKTSNKTNTFDKSKCKKSRTNSWRTTKPKVSFHRLMDDVRFVLSGFQNPLRSQLRDKALDMGAKYEADWSKNCTHLICAFENTPKYNQVKGFGRIVSKEWIVDCFKEEVLLPWRMYRLGRAPSPANSKSDADDEEDGDVTPTFTPATPKSSNKYSSTTSTTPKSANINAATVSTTPSSKNKHPNAASTNPRASNKRAVTTTANRNSSITSGRADDVDNGSDRNDAGVKLYGSFNKNSTTNNNNINNNNSTNNNTNDNNDNSFKNNSDGVDENDLNNKNSDTNKVDIKIKPNKNEDPKLQEDDGSSDDEDMDDEIGDDEIITAVAVNDGDHRSTRNDGGGAADDDDVERNKKQEYFKDDDVEDDVEDECFNCPTDSECDTDEEVRRFDEYQRKKKDVAKKSCCGVDTQEPSTSTSTAEHHRRSHYSSKHMQEIISSLPDLPSFFRGLNFFLYGDFSSVDRKCINRYIQAYDGIVSEYMTDGVTNVVTYEKWDNNFDEAKKDNEKLVFVHPDWLVECIELQKLVSNESYLIKKL
The following text describes a protein:
Function:
Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. Prevents actin filament assembly by forming a 1:1 complex with actin monomers, and inhibits the nucleotide exchange reaction of actin monomers (By similarity).
Miscellaneous:
MISCELLANEOUS: Present with 1470 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSTQSGIVAEQALLHSLNENLSADGIVIIIAKISPDSTSVHQTQVARSFEELVQLASQEREPLYIFYKPEGLDKYFFVSFIPDGSPVRSRMLYASTKNTLARQVGSNSLSTEQPLITDAQDLVDLKNFDSARPAGQNKPLTHDEEMQIEINKQQALLRKNTSVKLVSQDSASPLSLTFRVNSEKPINEILDSEGKNLIIFQIDPSNETIQIVQSDTCPSVDELYIDLPGPSYTIFRQGDSSFFIYSCPSGSKVKDRMIYASNKNGFINYLKNDQKIAFSKVVEIGDFVELDKSLLMATNKEDSLDHGSNPDLPNKSNLKFNKPKGPLRKRRT
The following text describes a protein:
Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis.
Subcellular Localization:
Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton. Nucleus.
Sequence:
MEEYHRHCDEVGFNAEEAHNIVKECVDGVLGGEDYNHNNINQWTASIVEQSLTHLVKLGKAYKYIVTCAVVQKSAYGFHTASSCFWDTTSDGTCTVRWENRTMNCGVLLCRPGWSAVVQFRLTATSASQVQVILLPQPPGYLELQAHAITPG
The following text describes a protein:
Function:
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
Sequence:
MVGVAAVKDVGFLLDRLLDPKQPISERFRVLFAIRNHHGDASRSALIAAMRDPSNLLAHEAAFALGQMQDPVSIAALREILCDVDGAHPIVRHEAAEAMGAIGDPSCVDLLRSVWRSDPAREVRETCELALHRIEISSSNSNPTNEDRVPKFLSVDPMLPASGDSSTSQLRQLLLDDSLPMHERYAALFALRNRGDRESTDAIAAALETSKSALLKHEVAYVLGQLQDMATVEILERTLGDPGEHPMVRHEAAEALGSIADPNCVELLTKFLDDPEPIVHQSCEVALSMLEFEQQGKPFEYLFQEIKVGSE
The following text describes a protein:
Function:
Probable transcription factor involved in plant development.
Subcellular Localization:
Nucleus.
Sequence:
MESGFSGGGGGSDFYGGGGGRSIPGGPGTVINVGNNNPQTTYRNQIPGIFFDQIGNRVAGGNGFSGKRTLADFQAAQQHQQQQQQQPFYSQAALNAFLSRSVKPRNYQNFQSPSPMIDLTSVNDMSLFGGSGSSQRYGLPVPRSQTQQQQSDYGLFGGIRMGIGSGINNYPTLTGVPCIEPVQNRVHESENMLNSLRELEKQLLDDDDESGGDDDVSVITNSNSDWIQNLVTPNPNPNPVLSFSPSSSSSSSSPSTASTTTSVCSRQTVMEIATAIAEGKTEIATEILARVSQTPNLERNSEEKLVDFMVAALRSRIASPVTELYGKEHLISTQLLYELSPCFKLGFEAANLAILDAADNNDGGMMIPHVIDFDIGEGGQYVNLLRTLSTRRNGKSQSQNSPVVKITAVANNVYGCLVDDGGEERLKAVGDLLSQLGDRLGISVSFNVVTSLRLGDLNRESLGCDPDETLAVNLAFKLYRVPDESVCTENPRDELLRRVKGLKPRVVTLVEQEMNSNTAPFLGRVSESCACYGALLESVESTVPSTNSDRAKVEEGIGRKLVNAVACEGIDRIERCEVFGKWRMRMSMAGFELMPLSEKIAESMKSRGNRVHPGFTVKEDNGGVCFGWMGRALTVASAWR
The following text describes a protein:
Function:
ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. Activation by extracellular ATP induces a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle; Receptor for ATP that acts as a ligand-gated ion channel.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSKAAGCRGFLHHVFDYETAKTLVIPHFGVGIVFRFTQLLVVLYVVGYVCVVQKGYQETDSVISTVTTKVKGFAYTNTSDMDPRMWDVADYVIPPQGDSSFFILTNLVVTPEQTQSHCPELPNPSTVCKDDCDCIEGYNDPRRNGIRTGLCENFSTTVKTCEVFSWCPLEVDTRLPKKALLAAAENFTVLIKNSITYPKFNFHGRNILPHVNSSYLAHCEFNRLTDPDCPIFRLKRIISEAEADFQEMAVKGGILGILIDWSCDLDWWAGKCLPKYSFHRLDNQNQGNDVAPGYNFRFAKFYKRADGVEERTLIKAYGIRFEVIVFGTAGKFGIVPAIVNLGAALSFLSLVPIVADWVMLTCMRKRDLYTKQKVTYLVESPDSEPVSNHCSEAQCSDVSCMFCSCSYLYAQVFNVSFVLPVFYFYYAGFNGDHLWHPMIHSSSTESFFVHQNGMCSKNAIQIIY
The following text describes a protein:
Function:
This is one of 3 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit. This protein has three domains. The N-terminal one is bound on the solvent face, the middle domain fills the space between the 5S rRNA and the L11 arm contacting the 23S rRNA while the C-terminal domain is on the edge of the intersubunit interface and contacts the A site. The protein conformation changes upon binding of a tRNA mimic to the A site, although the mimic does not interact directly with CTC itself, consistent with CTCs presumed role in moderating A site binding.
Sequence:
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPRLTAEELEAEVQAAQVAGLVAAGELSEEAAEAVLEGDASLEEVKAEASEDNAGTDSEDNSDAQ
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MAAEGSRSGRRSGRFTMTCACVLQRQRQARAGNVARLFQEPPPLPVAPAVENDGRTMQLFPVRAGAAMARQRLEMTKAPMTIFYGGQVIRVENVPADKGKQLMEMAQSVNNPPPPEKVVVVDVPDEEVVAEPSAAITANQARKLSVQRFLGKRKQRTDDPDDEEEASPSKKMDTGGDEPFEDVPYASWLSL
The following text describes a protein:
Function:
Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MKYGKVSFLALLCSLYVRGSLADPESEQEPLVFNPTEVKAPLVEQFQGAWSERWIPSHAKRFVNGIEEMSYVGEWTVEESSGPGALKGEAGLVMKDEAAHHAISYEFDEPINEPEKDLVVQYEVNPEEGLNCGGAYLKLLAEPTHGEMSNSIDYRIMFGPDKCGVNDRVHFIFKHKNPLTGEYSEKHLDSRPASLLKPGITNLYTLIVKPDQTFEVRINGDVVRQGSLFYDFIPPVLPPVEIYDPEDIKPADWVDEPEIPDPNAVKPDDWDEDAPRMIPDPDAVKPEDWLEDEPLYIPDPEAQKPEDWDDEEDGDWIPSEIINPKCIEGAGCGEWKPPMIRNPNYRGPWSPPMIPNPEFIGEWYPRKIPNPDYFDDDHPSHFGPLYGVGFELWTMQPNIRFSNIYVGHSIEDAERLGNETFLPKLKAERELLSKQESMEKQSMHVDEESNQILEKFLDVYDIIKAKLPPNVAEKVDYYVETIIETPEIGIAIVAVLGSLTAVILTCYFYFFASSSPASLSTGTTEAEKEQQEKFKQETETEKIDVSYAPETESPTAKNED