lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm.
Miscellaneous:
MISCELLANEOUS: Present with 45100 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MALAISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLTVPELCLLTDSFILTRLEQYYKNKVNERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWNKGKDSTFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVIYPVDETKPILQPTGPLLGGKADAVAAAHIAMETVVALLACALTPEKLPASLGGTSSGITGQLIRTIVDTIARSYNCGVVPGSRVRRIRRFLAGQNEGIVAEREYKGVVWTESHQEADLLSNTDAKDLTVVDRGQSTPFTNVSAIPSDDFVVQSGEVYLIDLKMASLEHCTKKGLVTLETVDSYTGKSHKAGELIARPGAYVRDFAQTHILKLKTSRQLLTKIDKQGVYPFKLSHLSSNFPFVHENEEELQSLKKDLKSFRLGMSEISNNYLCVESPIQIARWVPWDHILKATNPNGNLSYDATSTLTLPGHELPLPKLGVSAIKLKSLMNSTKESISLPVARECNTIVLCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQHELNPQDSIVQGIFQLATLAKDKRFGLLLKETQPMKQKSVETSNGGVEETMKM
The following text describes a protein:
Function:
Plays an essential role in chain termination during de novo fatty acid synthesis.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MRDPTLHKKLKRTSSWGLQFKAPTKVNATKVGAMDWSMVDPEKEVPNMVLDLGVERMIQDGLIFQEKFCIRIYEVGPDQKASVETLMNHLLETSINHMKKTGFIHEGLGSEEMSKYNLTWVVAKIQMVVDHYPKGDIVEIDNWKVALGKNGVCCNSSNERPYPTTVGLRQELLNRARPDLLKLFSPCNM
The following text describes a protein:
Function:
Plays multiple roles in growth and development. Involved in nonsense-mediated mRNA decay (NMD). May provide a link to the mRNA degradation machinery to initiate NMD and serve as an adapter for UPF proteins function. Required for meiotic progression through anaphase II of pollen mother cells. May counteract cyclin-dependent kinase (CDK) activity at the end of meiosis. May play a role in plant defense through its involvement in NMD. Together with EXA1, helps to restrict cell death induction during pathogen infection in a salicylic acid- (SA) and reactive oxygen species- (ROS) independent manner.
Subcellular Localization:
Cytoplasm, P-body.
Sequence:
MMTLQMDKTTASSSWERAKSIYDEIAELANKRQKAGNPPDPNLLQLLREKYEAIILESHTFSEQHNIEIPLWQLHYKRIEYFRLHINRVLASSTSTAAQNVKGPSKAEQIAQLKLQFRTFLSEATGFYHDMILKIRSKYGLPLGSFSEDQQSQNLSDKDGKELAEVQKALKSCHRCLIYLGDLARYKGMYAEGDSRSRQYASASSYYLQAASLWPASGNPHHQLAIVASYSRDEFVTTYRYFRSLAVEYPFPTARDNLIVAFDKNRQSYEKLFVPSKDSSKRLTGKGRGKGADISLKDATLVAGPEKDKVTIANEMLKAFSIRFVHLNGILFTRTSLETFFDVLASTSSSLREVISLGSAKELTLGIDTSDSALFIVRVVTMLIFSVHNSKKETEGQSYAEIVQRVEPARNSLTASFELLGLVIEKCVQLGDPSSSYFLPGVLVFVEWLACCPDIALGSDPDDRQTAVRNSFWNQFVVFFNQVLSLGPTFIDDVEDETCFSNMSLYDERETENRLALWEDYELRGFLPLLPAQTILNFSRKHSFGTEGPKEKKARIKRIFAAGKALTSVIKVDQNHVYFDSKKKKFLVGVKPADDFLDSHSSPPKACNALQDNQVMIDHNSPIMQLDQQIYMGEEDDDDEVIVFKPLVTEKRKEASDQIYVPSGGFRKSDQVTTMGDFKALSGSDVAFHENQILQARGNASIQVPASVGANLLGPLQPSTQSQAMHMQQVQTQVQVPASVGANLLGLLLTSTQSQAMHMQQVQTQAVNPQPAQSLAASRLQPIQSQVAQPLPSRVVHFQQTQAQVSHVSPAHSQSTSFGGGSKWSPEEAASLASSLSGFAQLGNGHVMRNEMQGNHGVSYYPAHSLPVHQSYNGNGMGGMPYSQSRTPEAVFPPKIDPVLSSGVVADGLGVQSSLAKKNPISRAFRHLGPPPGFNSVPAKLQKEPAPGSELSGNNHLPVDDYSWLDGYQAQSSRGVGLNSSLNYATSGKPEHLGSTGNGLNGPANFPFPGKQVPTSQVQADFPYFQNPQKDNFVDKNHQSTQLPEQYQGQSTWSSRHFV
The following text describes a protein:
Function:
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MTIKKYTLLTALSVTAFSGWAQGNNTTDNNDEMVVTANRFPQPKSSVLAPVDVVTRADIDRWQSTNINDVLRRLPGVDIAQDGGMGQRSSLFIRGTNSSHVLVLIDGVRLNQAGITGASDLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVINILTGRDKPGTTLSAGLGSNGYQTYDGSTQQKLGEDTTVTLAGNYTYSKGYDVVAGMPGAGGPRQPDRDGFMGKMLWAGLEHQFNEQFNGFARVYGFDNRSDYDGYTNYSNPLALIDTRKLSSRTYDTGLRYKNGIYASQFIASYNRTKDYNYSPLFGQHDITASLDEAEQYNLQWGNTFQLTNGMISAGADWQEQRTERKSSNQNTTADFTQHNTGIYLTGQQQISDVTLEGAVRSDDNSQFGWHSTWQTSAGWEFIDGYRLIGSYGTAYKAPNLMQLYSAYGGNANLKPEESKQWEGGVEGLTGPLTWRLSAYRNDIDQLIDYSNLTNGYFNINKATIKGVEWTGSFDTGPLSHQVTLEYLDPRNADTHEILVRRAKQQVKYQLDWQVADLDWSVTYQYLGQRYDKDYSTYPEETVELGGVSLWDLAVSYPVTSHLTVRGRIANLFDKDYEMVYGYQTPGREYYFTGSYNF
The following text describes a protein:
Function:
Involved in intra- and inter-cellular trafficking through plasmodesmata (PD).
Subcellular Localization:
Endoplasmic reticulum. Cell junction, plasmodesma. Note=Accumulates intracellularly in a polarized fashion, into punctate spots at the cell periphery. Located at both orifices of the plasmodesmatal pore of adjacent cells. Can move through plasmodesmata.
Domain:
The C-terminal part of the protein in required for plasmodesma localization.
Sequence:
MAATSDEQMNLLLSSFDQIYEDFKIGLNEINVYRSKSNVESSRREVLEISNKNLKEENERLKKLYTESLNNFADQLEHRTKCHSLKEELKRVNDENKSKEHEHRNALESLRQKHVTKVEELEYKIRSLLVEKATNDMVIDRLRQDLTANKSHIQAMSKKLDRVVTEVECKYELEIQDLKDCLLMEQAEKNDISNKLQSLQKELLISRTSIAEKQRDTTSNRQVETLKQKLMKLRKENEILKRKLSSS
The following text describes a protein:
Function:
Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation of proteins such as tubulins (Probable). Via the deglutamylation of tubulin, regulates the localization and velocity of kinesin motors and the structural integrity of microtubules in sensory cilia. In male CEM sensory neurons, regulates the cilia release of bioactive extracellular vesicles. Also regulates microtubule dynamics in uterine muscle cells.
Subcellular Localization:
Perikaryon. Cell projection, cilium. Cell projection, dendrite.
Sequence:
MPSDSDDVAAVKQPWSQLIVDISNFLSEHPQSKTSQALLPSCNGVWSDEEKLELIEAFGHKKQSHLTKSGVKAVLAAFEGDRTQPDVIFLCRLLHLIFSHFSSENDRKKEKYIVKCDVIATLTRITRKRIIMTLDVTDESSIDHNLDEVLWKLLHKIGLKDPRVSLKVRMGGLISPMCKLFIQKDTLPELFLPFFIKISRSPRNGQAIGRYEGFMTRLLVKIKALDASDQTSQVLLLDKHLQLLFFTMKNKRTRTQLLRENICKYLLEVLRRHLASSSNSRPTRLLSSLFGTFDKSLSAAHTEVVIGTIAILRLLSNFKKARDELKNLQVLDICSRELKEFWSDEWKTGPKSRIVDSLSALCLRCMSPLPYPLETRRFPIDFPLPTATPSTPGGHGRIRNSSSINISFDNGRSSDEDGMDEEDEAFVRDDDDEGKDDRGSDDDDGKDDDEINGALPKTTRLNPQQLAKYAPFFVENEQGTLQPTFSMIYQTNQESWRSICEKTRHVMPIHHHLPIEMFNTPTRIREKTAKTSNNMKKMIIEELDKPERSATSNQVIYDLDTAAFDGLPSPELPFVTGGGKLDTSKDLQFDSRFESGNLRMVIQVAPTHYELFLSPDVNQLRDHYQWFFFQVSNMRKSVKYTFEIVNCLKSTSLYSQGMQPVMYSMMESANGWRRVGENVCYFRNLYINENEEKKNVEEQKKKKYYYSIRFNVTFQNTGDICYIAYHYPYTYSFLNSSLSMLKKRKQENVYCREDVIGHSLAGNPIKMLTITTPASAAEIAAREVIVLSARVHPGETNASWIMQGILENLLCRQSNEMYRLRESFIFKIVPMINPDGVTNGSHRCSLAGIDLNRMWDRPNEALHPEVFATKAIIQYLCEVANKKPFAYVDIHGHSKKWDYFVYGNNASESWRADDVLDVGAAQLEEELHLALPKALEATCPSRFNASECRFNITRAKESSARVNVWRQFGVSTAYTLESTFCGFHKGQNSGYQINTSDLKEIGRDLLHSFLEMTKT
The following text describes a protein:
Function:
Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MLHELLFVLSGYDGDVFVLDKSTNLVKVAKNLPFVHPTEESLLNRICILATHYIKFKTYIDLTNNSKVRHQGSYKKAFVKGLELILEPYLKLLVDLEKKLIKDSHLTVAYIQYATENYQQWFPAVSLLVDQVSNDRVHGCEVLDLLHKSSITGVQCVRDNILNGFDFCLIRILKCCHTVLYRQLLSWMLHGELTNSTGEGSRWGFFIQHHLEDHHNVIKADNDDDDDVEKKSKRIHLYEVNLAQLPSYISVRVAQKILFIGQSVDLFRGNRTKGYHSMWQPFKESMMSLREEEFSRDIDELSKLDVFDAIKFESTIDKIKTYVAGQLRNLMVDEADIQSNLRRFKDFFLIGRGELFLTFIDQSQHLLSKPPTLATHRDVNLAFQHAARDHSLDEKLYKQFQLVIQDANSAQSITATSSSSKFLQTRESGWNCLRMVAHVQWPLHIVFTDVVVHKCVFAAWYSQLFSFLLYVKRIQIELQQCWSLQMQQRHQHCNKLAKSEQNKSPLHHSPLKWRLRNHMAFIVDNLQYYLQVDVIESQFSILFDKIQSSKIDFEEMLLAHETFLNSLLAQSFIHVNQVNHCLMALLDLCHSYYGLVVHAQAELTSVQKQKLEDISKDFHRQSGFLFVILSRIRNNPHLTQLLLRIDYNNYFSKSKFSSTLLTKQVHSAS
The following text describes a protein:
Function:
Component of SCF (ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Part of the phyA-mediated signaling transduction pathway leading to the regulation of gene expression and hypocotyls elongation in response to red and far-red light exposure.
Domain:
The kelch repeats form a beta-propeller structure involved in protein-protein interaction; The F-box is required for the interaction with SKP1A.
Sequence:
MAEQETTSNINTINDQAEEETRTKSQPLISGLPNDIAELCLLRLPYPYHALYRSVSSSWNKTITNPRFLFSKQSLSISSPYLFVFAFNKSTARIQWQSLDLASGRWFVLPPMPNSFTKISSPHALSCASMPRQGKLFVLGGGDVNRSAVVYTALTNRWSCISPMMSPRTYFVSGNVNGKIMAVGGSVGGNGEATTEVESYDPDNDTWTVVKKLPMVLAKYDSAVIGKEMCVTEGWAWPFMFPPMGQVYDSDEGTWREMSGGMKEGWTGVSVVIRDRLFVISEHGDFPMKVYCSDDDTWRYVSGEKLQGEKMRRPFAVTGADDRVFVVASGINVAEGRVSEGQNGDFSVEWRMVSSPKSSIQFSPASCHVLYV
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MERDFLGIHGRDSGNRQDAALFGGSAVQWPFSNVSTMQPFVFYKAAQEEKARNYFFDKHSSSSRFHPLPSMAVFEPSQKASHAVASQKSFGLGRQSINQHPMHGYQPQSTGSSLDATTCHMIPVNMGGPFFKVQAAHSGPNIAVTSLEQLPTGGGTAVNSPIGGPAGGAFAPRNMPKPSHMTAQLTIFYGGCVNVYDDVPLDKARAIMLLASKGSNVSSNAINPRSEAPLPAAAPVPAKVLGSNGISTKQTLIPTPIYVVAPCSGLSSPISVASHARAAAGGGSSNTDDAPRPKAVVAPLVPTGLHDTSKAPTTALGSRTATNNTPRAVPQARKASLARFLEKRKERMTNALPYPSSCSNMTQDKGGRGFESCNSPSKSSSAEISLSTYREDSWFLAHPKSSIGSMESLGTKLTI
The following text describes a protein:
Function:
Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. It is essential for viability while oxa101 is not. When both are deleted the cell is non-viable, suggesting that oxa101 act as a back-up for oxa102.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MFSVIGRGIKFSSKSHYSVSCFLIATQGAKIRQIHTHNTFFKNFSFAKLGRNQRTSSLIKIHNSSTSFPKSRSEKVVYTPSLPLSSSVLASFSFLPHNILQNGLNTLHIWSGLPWWASIAACAVAMRIAVFPIMLKMMKTSAKLAIINPKVAEHMSVLSKAKAEGNSELMMQATTQIQNLYKVNNVNPLNLLSAPVFQGILFISFFYALKTMAGVPVEGFTDGGFWWVNDLSQPDPLHIFPVANGLLMLLNIELGSETGSNKVAMSPSMKKFFRFLCLASPLFTMNFPMAIFMYWFPSNVFSVFQGAFLRSSTIRHKLGLPEVPSAMPVPNAQNESFVKSFTDIVHGVQEKGKYPQASEILDATRFLKTDTNNEQKPTNNSTITKATTLSDNSQNDKSSSVTKPTEKKD
The following text describes a protein:
Function:
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
Subcellular Localization:
Nucleus.
Sequence:
MTSGSTNSSSSGAGASQTLTLTATEASRTQATDSDGILHLRPGPGRSASATTSSRRVVWTQETVDNEGLGRKKSKICCIYHRPKAFDESSDESSDSPTDSSSDSDEHSTDSDKDAPNYSKAIKDKLKQPNSNAHHPTHHPHDTCQHAHSNHASKSSKQKSKRKVRSSARSQTITKEQTDGPTDQHHSHADNHAKPFTPNAYERGPR
The following text describes a protein:
Function:
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
Subcellular Localization:
Nucleus.
Sequence:
IASNSWNASSSPGEAREDGPEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKDKALQSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKPFAQPAYPIQPPLPPTLSSYEPLTPLPPAAASAPVWQDRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTIQEGPGAFYGVSSQYSSTDSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD
The following text describes a protein:
Function:
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
Subcellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MQQPQPQAQQQQIQPLDFYQEEYKDAVRFSWNTLPATKLQSTRAIVPMGCLYSPMKDLESLVLVQYSPLYCKCGAILNPYNQIDFRNKQWTCVFCSSKNAFPKHYADHITETQLPAELKKTSTTMEYILSNQQAAPTTFLYIIDTCIPQEDLQAIRDSIQQSLSIIPPDSQVGLITFGRNVFVHELGFQECPKCYSFKGSKDYTTQQILEMLQVSTKPEILKRFLVPLNECEFSFNSILDDLQCDPWPSQPGEREVRANGSALKIGSTLVESATQFSKILFFVGGPCTIGPGQVVGLKLEETIRSYLDIQKDNPNTQYLQKAKKFFNEIAQRAIKANMTVDIFAFTLDQFGLLEMKQLAEKTGGVVVMQEKFDSDMFKETYKKLFDKDASGFLKMGFGSKIDMFISKDLKVQGGVGPCISLKKGGPMVSEVSLGEGGTTSWYSGGLDRNSTILFMFDLSPTKDTSFSQCAYIQFVTMYRHSSRLQRLRVTTIQRRFADHNNIMDMIRGFDQEAACVTMARVGILKAESEESIEVLKWLDRSLIRVVARFGSYRKDDVSSFRFPQEMMMYPQFMYHLRRSHFITTFGASPDETTFYRASLSRECVQNALVMIQPALLQYTIDDPVANAVNLDIQSMKPDVVLLLDTYFNVVVWYGEHVQKWIEEGYYDNPEYEYIKELIDSPNSDVQYILEDRFPVPKLIKTYFGHGQERYLKSRVNPSVNTVQNENVESGNYITDDASLKVFTDHLIRLAVQTVQ
The following text describes a protein:
Function:
Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAVPAALILRESPSMKKAVSLINAIDTGRFPRLLTRILQKLHLKAESSFSEEEEEKLQAAFSLEKQDLHLVLETISFILEQAVYHNVKPAALQQQLENIHLRQDKAEAFVNTWSSMGQETVEKFRQRILAPCKLETVGWQLNLQMAHSAQAKLKSPQAVLQLGVNNEDSKSLEKVLVEFSHKELFDFYNKLETIQAQLDSLT
The following text describes a protein:
Function:
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Sequence:
MSNKRIEQSEIEKYWEIFASLSNGGTHLTGAQAAPVLKNSQLRDDQLERIWDLADVDNDGNLDFEEFCVAMRLIFDLVNGEYADVPPALPDWLVPESKAHLVQASRALTGRQVQFERVEDDDDTPGLKDGFDWYMSPSDKSKYEEIYAANRDGRGDITYTLYSSLDVPDTDVRSAWNLINPSAAPAISKDATLAFLHILNNRHEGYRIPRTVPPSLRASFERNQIDYQLDNQRVASPAQKWGVTGGEETSTGRKAKFGETYMSRLGLGGKSSYRPAGTDFSGTKTTEDWEEVRLKKQLAELEAKIEKVEAAAAARSGGRRDTKPALVKRELEQLLDYKRRELRDLESGEGRSKVGASLKGVADEIATVREQVDGLEAHLRSREQVLEELKQEIENEKISR
The following text describes a protein:
Function:
May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 and RND3. Promotes RHOA activation mediated by GNA12 and GNA13.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MNNGRRRSSKPSGSPQLFRANPPKKDGGLSDLLLLSPDVLDDATRRELLQDVLRQRRTSPSSVDRPSNPGAVPGDAHTDKEPFAHQLRTRVRSGSNSNSDILVTAMAARLKDLESQHKAYQAEMNELHAKYRQLNDKYQRERQLREEAETAVLTLYDEKELLEAELREMEAAHACASGAKSHHALSPHNRAGKGIHDTKASPSHSPPTPSRAVKVDLFSGDFTDGSTDDGAKATEKEGPTHSVNTARPDTVLFSPQKVGGLPGKRQAASAVAGSSPQPPCRRYSVSSVDMELLTKNARILSDYVGWKGVFKQGNQAGIRERDVVRVVVYKNGICVNQGPFRPYGWALCDAFLDDLIEGFYPYEFKERYPDGFPIEVVDRTGETCETDRTGAAHGSEAASQANAGTLFPNEGGRRLGAAPQNPGRNPERVHTLDEQKNIGYTPISVEAFLKKVPAQKVTASGQLLSVRDGVAAFMGVGATGASSASAPRALGTIKHVSAAEAAYRRKVAQQQQQQQSASPVTAASGVVSSMFVGNLIAVLIRLPDGHKITLHMAPEDTVASLRKEFVAAAPSFREARYELCQAFPLKQEWNEHQRTFASLGVEKSCTLMVKLMKQA
The following text describes a protein:
Function:
Involved in the biosynthesis of homoterpenes, attractants of herbivores parasitoids and predators (e.g. predatory mites and parasitoid wasps). Involved in diterpene (C20) biosynthesis. Catalyzes the conversion of geranylgeranyl diphosphate to (E,E)-geranyllinalool, the precursor of the insect-induced volatile C16-homoterpene TMTT.
Subcellular Localization:
Cytoplasm.
Domain:
The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
Sequence:
MKSSYGSSSNDLHAFVNEIKGEIQLSNINLDPYSFVSPSAYDTAWLSMIEEDINVDDNELKPMFQGCLDWIMCNQNAREGFWMNSTSYTTVADGRDEDGEKDMCILTSTLACVVALQKWNIGCFHLHKGTRYIERNTEMIIGKYINEEGSYPRWFAIKFTGILELAQKLGLHFVFSSRCIEMIKGMFYQRQEIIQREKLVHDCNYKPLLAYLEVLPSKLYVTNQEDIIVKSLDSMDGSLFQSPSATASAFMLTRNTKCLAYLQNLVQKCPNGVPQKYPLNEDLIKLSMVNLIESTGLGEFFGIEIEHVLEQVYSRYEEKDFERMPMSYLADQLHKDSLAFRMLRMHGRDVSPRSFCWFLNDQETRNHLERNIDSFLLVILSVYRATDLMFPGEHDLQEAREYTRNLLEKRRSIKEKMIMHELSTPWIARLKHLDHRMWIEDKNSNVLSMEKASFLRLHSSYSDKLTHLAARNFEFQQAKYCRELEELTMWVKKWGLSDIGFGREKTTYCYFATVTSLPYEYAIKFGKLAAKTAILITIADDFFDEKGSFNDLEGLTKAVLRWEGEELKSYGNIIFRALDDIVRETANTCRTHHKTDIIVHLRNIWGETFESWLREAEWSKKGHTSSMDEYIRNGMISIAAHTIALSISCLMEPCFPHNKLKPGNYDSITTLLMIIPRLLNDLQSYQKEQEQGKMNSVLLHMKNHPGLEIEDSIAHIEKIIDSKRKEFLEHVLVDGLSDLPKPCKEIHMSCCKVFEMFFNKKNRYDSNTEMLHDIKKALYDPINVYELSEMEPMPLMAHGDEYMILPLLLNSLPNILEFKRKDGYGAMKTSMCFGRSYRVNKRVMASQLDDQHKPLKIVASQRKPVPMMQSIFAPCFY
The following text describes a protein:
Function:
Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine.
Subcellular Localization:
Cytoplasm.
Sequence:
MSGRPKVTKIQVRQTASRLLGVAIETIIGVRQLESFEDCNYHIKINNKENDCNDQFVLKILNLQSNQIKDAIECKVLACQFLSQSGIQCSKPVLLTNGSYMDMVTFSSSDSAENTVHNDHIVFIVEYLQGILLRDMEPKFDNTLMYQLGQAIATMDKQLLKFQSHQRKFFTGDWSLHDNFATLDRYLQYIHMASKKDILTEIFQSCKIAMQQILPQLKTCFIHGDVNPGNVIVSTSSSKSTSVSQVGSSHQGIGVIDFGDFHYSYLIIELAIAIAHVMAETTTDAIANSGHLLAGYLSVVHLNPKEFNLLYDVILARLFQLMVLSEYVYTLDPSNSYVIDRVPNYYQAITMLWKLSREEVYQRWHDIIQSY
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MSKAETGVLQANAVDVHRSDVPDERDGVESHSDDGEDNMGEKSATLITGRKRKLFELRLKMNGARKANQSAMVVEKKKTEVLATESRGMSKYGKAPKSSDDKIERMVKELKDRDEKRQSFSRRRRFHEEKDIDSINDRNEHFNKKIERAFGKYTLEIKNSLERGTALPD
The following text describes a protein:
Function:
Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and also controls the poly(A) tail length. Increases the affinity of poly(A) polymerase for RNA. Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation.
Subcellular Localization:
Cytoplasm. Nucleus speckle.
Sequence:
MQFYASNEEISRNQSGIVSERDMEEEEHEVYGGEIPVEGEMEGDVDMSAGDDDAVKELDEMKKRLKEMEEEAAALREMQAKVEKEMGAVQDPAGTSASQAGKEETDSRSVFVGNVDYACTPEEVQQHFQSCGTVNRVTILTDKFGQPKGFAYVEFLEAEAVQEALVLNESELHGRQLKVLPKRTNVPGMKQYRARRYNPYVGFRRPYAPPYFYSPYGYGKMPRFRRSMRYMPYY
The following text describes a protein:
Function:
Dethiobiotin synthetase involved in the biotin biosynthesis pathway.
Sequence:
MNSKSQQQEQQPIVFVTGTDTDVGKTFVSTLLVHKWKAAYWKPVQTGIESDQGDSETLKNFKIAASTWQPPIFTPTYALQKPLSPLQAMEYEPNVDIRLLDFVVPEEWSAENPLVVEGAGGVCVPITRKLEITTDLIKHLIETSGHPVYVVVVARSGLGTLNHTLLTWNHLCDNGLRSHLFGVILNGEPNEGNVQALKKFGVNIMAQVAQCTTAHDQDMELHELPSVESLMTQQDVE
The following text describes a protein:
Function:
May be involved in photoreceptor outer segment disk morphogenesis.
Subcellular Localization:
Cytoplasm. Photoreceptor inner segment.
Sequence:
MSDVDDLIEELFPKKEGGRAPPEGKGGAACEPPASQSNWDDTDEANSEAETTTRNRGTSVSLEAAASTTANVGDGRGEDFDDSDESVEETVMGGRHTVPFPPTPGNMSMACNSKCFVTNVGSGELRHPSVAQLLLTGEGKYDKCSSNEQLLLRKGAFHALKADAGNGCTDKTADEDGRKGGCPFILCRKCNYTVIRLQDAEWDDEEGKMDLYLTVRNFYPDWSRLASSLPVGQMRRGEQNTVLKTCPDSAAYCCQCSWLTVKCAQEVIDTRVTDHTKFVGKELTCCFATQLPLISGEKRRPPLWVCGGHVPKH
The following text describes a protein:
Function:
Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria. It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MIGNGTAKDSLTSVDHAIAGAISGFVTRFICQPFDVVKIRFQLQLEPIKSSHPTAKYTSILHGTLCILREEGITAFWKGHVPAQMLSVVYGGVQFSSYEYLLKRSDSTLGREAVIRWSNTVHFACGFTSGCVSTAVAHPFDVIRTRLVAQLEPKTYTSISQAVRLMWRQEGPRSFYRGMLPTLLQIGPLSGFQFGFYHFFTHLWTVLLEDDANVTGTRSVACGALSGIVSKTLVYPLDLIKKRLQASASFSRPRLNFGRYNGFLHCVRCIFVQEGFLGYFKGYLPSVLKAMATTSSYFASYEAACEMLKYRHS
The following text describes a protein:
Function:
Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC.
Subcellular Localization:
Cytoplasm, P-body.
Sequence:
MSTVRSSYEVGLDFLQFLGQRISKTDRNELRDIYNLEFKRDGSEEPSFAKVIRALSCFKKARSSHGKIFFQWKPKMRVYYCDQWKSFVQQNTSPSAPDSDPASSSSPRPTFKPILTPKKKLATEILNKLRSKRAELIKDKGGIEISSDPKATKGNVSFTIEELGKLFVVKFHIVNQSEGCIYFTYYTALHKMRCFTLVDKRRVNRVSPLLLCPGEDYDVEVHYNVNHPGHFPATMYFEFCPEVDPPGTAKPFCIVRELEAVVRTGLAETLGPESPYNPKQNRRLRPKSKVVEEGVPPESSITHDLKNMMKMNQYRYPAYLKELAKYKLEDSEHLPASLKQHLPRVRRLLDTQLCMKNYSERFHLLLHLEEIQMEVDIKKYDLYGKTMTLDKTNKKLLILKVPGVAENRPSVLRGDKLNVCLSDDRNQPITVYEGYVHRVELDKVILGFSRKLLQKFVNNMKFDVEFNINRFPLRLQHRAVELAVQHALGNVLFPSDKDTGHSELPHLSMFNKDLENNPEQKAAVQHILSGSSRPAPYLIFGPPGTGKTVTVVEAIKQVDKSKAQSHILACAPSNSACDLLCERLLGHVDAHRIYRLCAPSRDPRTVPQKLLKHSNWNEAQDSFLLPSKETLIGYSIIVVTLVTAGRLVSGGVAMGHFTHIFIDEAGQAVEPECIIGIAGLLDPLKGQLVLAGDPQQLGPVLRSPLAQLHGLGQSLLERLMKRNALYQKSQDDNSKYDSRFVTKLLRNYRSHPAILKIPNELFYENELQVFANQMEREAFCQWEHLPRKGFPVVFHGVMGKDEREANSPSFFNVTEIEVIVNYLNNLMQTQGKKGLPKLGPNDIGIIAPYRKQVEKIRKALNTVGELKKWKDIKVGSVEEFQGQERKVIIVSTVRSSVNYVKMDQDFNIGFLSNEKRFNVAMTRAKGLLIVVGNPVILSKDPTWQKFIQYCEQEQGYTGFDYKDAEGEEDVVSRLASLKISSDDTDESPLQQHVHPEWRAEQ
The following text describes a protein:
Function:
Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. May regulate the activity of some transporters.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm. Mitochondrion. Nucleus.
Sequence:
MKIPLTAGFLGQAADREAAGLVVDMICQKKMAGRALLLAGPPSTGKTTRALGISQELGSKVPFCPMVGSEVYSSEVKKTEVLMENFCRAIGLRIKENKEVYDGEVTELSPEESEIMTGGYGKSICHVIIGLKTIKGTKQLKLDPTIYDALIKEKVVVGDVIYIKSNSGAVKRVPFCPMVGSEVYSSEVKKTEVLMENFRRVIGLRIKENKEVYEGEVTELSPEESESMTCGYGKSISHVIIGKKTVKGTKQLKLDPTIYDALIKEKVAVGDVIYIESNSGAIKKVGISDAFATEFDLDAEEYVPLPKGEVHKKKEIVQLISVLLFHMVNIFYSLAMEYQRSYSAEAMNRIYEIKGRKHTSPLAICVGDVHDIQRYAMTDHLPRGLLDCLLPGPVTVVLRRGESSILEKLLNPRLESIGVRVPDYNFIREIACGSRSALALTSANLNGQPSSINIKDFDNLWEHCANVYDGRILPTGRAGSTVVDLTKLGKYKILRLGSAKEETIAILERHSSLEDGTGD
The following text describes a protein:
Function:
Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. May act by regulating the GPI-GNT complex; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MATGSDQAVGMGMVALSALIFTYYTIWTVVLPFVDDDHIVHQYFLPRPYAVIIPTVAGVVALSAIGSFFGYVMLQDKMKKKAK
The following text describes a protein:
Function:
Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
Subcellular Localization:
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Domain:
The PX domain binds phosphatidylinositol 3-phosphate (PtdIns(3)P) which is necessary for peripheral membrane localization.
Sequence:
MSTRKLNMLTPEPIHLLEEGGDNSEEFVVDEGCQVQRIYVGDGSITTSDEAKFTIWKVTTELIVHKVEPVRVSIPLEIVSYRRYSEFDQLRAEIISKIGKNVQVPELPPKVYWYDYWRFSKINLNRHWLNKRRQGLDNFINKIIKNKDIMESCAKEVNEFLGVSSDVSTRTNSE