lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity). Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (By similarity). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (By similarity). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C (By similarity). May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (By similarity).
Subcellular Localization:
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein.
Domain:
The MYO6-binding domain is required for autophagy-mediated degradation of infecting bacteria such as Salmonella typhimurium, but not for bacteria targeting to autophagosomes; The LGALS8-binding domain is essential for the recruitment to cytosol-exposed infecting bacteria; The CLIR (LC3C-interacting region) motif is required for interaction with MAP1LC3C, but dispensable for CALCOCO2-mediated autophagosome maturation; The LIR-like motif is required for interaction with MAP1LC3A, MAP1LC3B and GABARAPL2, as well as for CALCOCO2-mediated autophagosome maturation.
Sequence:
MEKTIEDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCRYTFTQNFIPRQKDWIGIFRVGWKTVREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDQDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSCVSLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETEQLEHLKKENGHLFLSLTEQRKDQKKLEQTVEEMKQNETTAMKKQQELMDENFDLSRRLSEKKMIYNALQREKERLEGENDLLKRENSRLLSYMGLDFNSLPYQVPTSDEGGAGQNPGLVYGNPYSGIQESSSPSQLSIKKCPICKADDICDHTLEQQQMQALCLNCPICDKIFPATEKQIFEDHVFCHSL
The following text describes a protein:
Function:
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGACVVMTDINISSGLDSNATGITAFSMPGWQLALWTAAYLALVLVAVMGNATVIWIILAHQRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPGTRAVIAGIWLVALALAFPQCFYSTITTDEGATKCVVAWPEDSGGKMLLLYHLIVIALIYFLPLVVMFVAYSVIGLTLWRRSVPGHQAHGANLRHLQAKKKFVKTMVLVVVTFAICWLPYHLYFILGTFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDKMELTYTPSLSTRVNRCHTKEIFFMSGDVAPSEAVNGQAESPQAGVSTEP
The following text describes a protein:
Function:
Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Subcellular Localization:
Mitochondrion.
Sequence:
MTILQEFKFARNLLGQNYCRWFSTSKRYRQGDSDKEEPSVEDIQKIVLNTALEFVPIHGWTVQSLSEAAKHEGYPGVAHGMFPRGGGDLMHHFVKECNSQLAEQLALDTSKEVEEGERKKTCAVIRDALQTRLRMIIPYHAQWPEAMVLTARPENVAEHFNNLANLMDTIWYHAGDKSAHFNWYTKRISLAAVYKSSELCFIQDKSPDFEETWTFLDNRLTDFTRFAKLRGDVQSFDTVRYRLVAF
The following text describes a protein:
Function:
Cadherins are calcium-dependent cell adhesion proteins.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MRGVGSAITLVIVISLQIILPSEGKFFNKLINQAKRNRVKRSWSYPVISIPETTDRDPPFVRKNILDITNDNPNVKTYELQNEDPTKFAIEFSAVDPSAGASIWQLVGLDRDVPGGDKYIFYAVVRDAAGNELDRVTLEVVVTDRNDNKPIFDISTLQGSVQEGVSPGTPVMTVVANDADDPKSLDQNGKVNYVLGPEEEVPPAPGGRRRFAISPTGVITVVGDLDIETAPTVNVVIIAKDGFIGASSGWSASATATIQIQDANDNKPVFQNTPYNAKQGELLPLRSTVFTVSATDADIDLENKGVTFEIVAGNDDNTFIVQSYPRGAGASTGDIILNKNLDYENGPKQYTLLVKAFNAQASNSGVQQFQATETVIVNVLDENEPPVFINQPYAGNIVENDVPKPNIAFVRAQDYDFGGNQTVTYGMVSTEGWFTIAADGAISSVGPVDREHPSVNQTNSVYTLVVSAIDNYRVKATATANVAITIGDKNDNAPEPDGPWTVTICEKPPTPFVTNIKIKDLDEPQNGAPFSVSLNDNSGLWVFKILSGDPMSRSINTLTKSFDVAQQSKYEVPIIMSDGATPPEPKLTSTNTLVINICRCNDNGEFNCEKMVPVAGAGFPVAVLIAIIAAILILLIIVLAVVAYRRRQQAGLEKEVLLDDDDVRENLQAYHDEGGGEEDNDGYDISALQAQPPNTGKPKVVDVQPLGGAQPEIRRPIQPDTDIGNYIGDAKQQADNDPTAPPFDSLLVFDYEGQGSDAGSLSSLNSGTTDASQDYDYLNNWGPRFKKLADMYGGGESD
The following text describes a protein:
Function:
Induces contraction of intestinal smooth muscle in isolated guinea pig ileum. May induce relaxation of arterial smooth muscle. May target bradykinin receptors (BDKRB). Lacks antibacterial activity against the Gram-positive bacterium S.aureus and the Gram-negative bacteria E.coli and B.dysenteria, and antifungal activity against C.albicans.
Subcellular Localization:
Secreted.
Sequence:
MFTMKKSLLLLFFLGTISMSLCEEKRDADEEETEGEAKMEDIKRAEAVPPGFTPFRKP
The following text describes a protein:
Function:
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Sequence:
MDDVEKAIILSFDESGSVDSALKLRAISYCQQIKEAPTICRVCVEKLRFCPIMQVQFWCLQTLQEAIRVKYASMSSEEKEFIRKSVFSIACCYDEESGGILAGPAFIKNKLAQVIVTLIYFEYPLIWPSVFVDFLPHLSKGGAVIDMFCRVLNALDDELISLDYPRSNAEVAVAAQVKDAMRQQCVPQIVRACYDILSMYRNSDSDICAAVLDTLRRYISWIDIGLIANDVFLPFLFELMLFDGLSEQLRGAAAGCVLAVVSKRMDAQSKLSLLKNVQISRVFGLVSDDSDSELASRVASLLTGYAVEVLECSKRLTEETKGTSFELLDEIGREEEDRMTEYRKDFFVLLRSIGRVAPDITQAFIRNSLDAAVTSTGGNIEEVEAALSLLYALGESLSEETIRSGRGLLRDMVPMLLASKFACHSNRVVALVYLDSITRYAKFVQENTQYIPMLLAAFLDERGIHHSNINVSRRASYLFMRVVKSLKSNLVPFIETILQSLQDIVAKFTNVDSSKALSGSEDGSHIFEAIGILIGMEDVPVERQSGYLSSLLTPLCHQVEGLLSNSKTLIIEEAPGKIATIQQVIMAINALSKGFSERLVTASRPGIGFMFKRTLDVLLQILVVYPKIEPLRSKVMSFIHRMVDTLGASVFPYLPKALEQLLAEIEPKEMASFLLLLNQIICKFNKLAHNVLEKLFPAIAGRVFSIISREAIKSGPGVNTEEIREIQELQQTFYTFLYDIATHDLSSVPGFQKFMIEAFTAHCCLYSVLDRSFEFRDANTVS
The following text describes a protein:
Function:
Indole prenyltransferase; part of the gene cluster that mediates the biosynthesis of terrequinone A, an antitumor agent. The first step in the biosynthetic pathway for terrequinone A is formation of indole pyruvic acid (IPA) from L-tryptophan by the aminotransferase tdiD. The nonribosomal peptide synthase tdiA then immediately converts unstable IPA to didemethylasterriquinone D (DDAQ D), via condensation of 2 IPA molecules. The symmetric connectivity of the 2 IPA molecules is thought to arise by head-to-tail dual Claisen condensations facilitated by the TE domain. TdiB then catalyzes reverse prenylation by transferring dimethylallyl diphosphate to carbon atom 2' of DDAQ D, to yield asterriquinone C-1. Finally, tdiC and tdiE enzymes robustly convert asterriquinone C-1 to terrequinone A via a transformation involving regular prenylation at carbon atom 5, which requires elimination of the hydroxy group on C-5.
Sequence:
MATEYWSRHLRSVLAPLFAAAGTYSPEDQESHLAFIDEHIAPNLGPLPWEPHGPYSTPSSLVGSPFDPSINIVSSGKAKVRFDFDVISPPDRTGPDPFAEGSAREILHRLADLVGADTQWMGYLMDALYLTPAEAEVAKTKLPPGVAIPPSSVGFDFDGPERTLKFYIPSVRKALATGQDVSELMLKTLRGLQPLGSELVPAMDLIASYLSTRTNDAMLPLVGIDCLDPRTHKNARVKCYLHTSSNSFAVVRDVLTLGGRLSDDTSLKRVETLKSVWPLLINELEGPQSDAATMDESWSKPERLNRTGYSGIQYTIEITPGQAIPDTKIYVPLFQYTDSSEVAERNFESALKKLGNEWGLSGKYRSVMQEIFKDVENYGQTYASFSYTEGKGVYTTSYVAMPIKDEGGGSLAGDFGFRN
The following text describes a protein:
Function:
Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane.
Sequence:
MKLYSILVFHKNVDTSDVKLFKSECDLSSFSFFQRGSVQEFMTFTAKLLVERSGLGARSSVKENEYLVHCYVRNDGLSAVCVTDAEYQQRVAMSFLGRVLDDFTTRVPATQWPGIRSDKDCSYTGLKDLLEKWQNPREADPMTRVQEEVEETKMVMHNTIQSVLDRGEKLDDLVKKSENLSDQSKMFYTSARKMNKCCNYV
The following text describes a protein:
Function:
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
Domain:
Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
Sequence:
MSAPQLHPRTIDEVRAKADLVDVVSERVVLRKAGRDFKGLCPFHEDRSPSFYVSPGKQIYKCFACGASGDVFKFVMELDKSAFGEVVLELARRFGVPVQTLKPEQKAEYTRKLSKQQQLGEILELAAQFYSYALWGERGAAARQYLLEARALSEKTIRQFRLGFAPEGWQSLYTYLVDQKRFPASLVEEAGLIIPRSSGQGYYDRFRHRLIIPICDLKGKVIAFGGRAMGDEQPKYLNSPETELFNKGQTLYALDQARESVGRTDGAIVVEGYFDAIALHQSGISHVVATLGTSLRTDQIKQLLRYTESKRVVLNFDADAAGVQAAERAIAELRPLVVKSGVQLRIVALPAGKDPDEFLRSHPPQEYLKLASEAPLWIDWQIERLFAGRDLSLAADFQQVSQGLVELLSGLLSSMTRAHYIHLIAGQLSQGNGRLASQLEDELRRRIRTHRWGGGDGKSKKKREPFPPACFQAEVQLIQIYLHFAEYREDIHRGLDEHDLEFSVLHHRQLWQKILQLREEIGEDDDVVVALRTMYAGDPELNQRLGQLLWLNEHNRIALMRPRMVIRAGLATLQLDRCERRYNYLNQLCDEAERRGAWEEADYFVEQRNAEYHRINDLKTHLTLKLGEISETAVWQES
The following text describes a protein:
Function:
JanA and janB regulate somatic sex differentiation.
Sequence:
MNRLQLLSKGLRLIHKMSEEALAGVPLVHISPEGIFKYVMINVIDGGDASKAVIRGFADCTWHADIFEREEDVFKKLGLRAECPGGGRIEHNPDKKYLKVYGYSQGFGKADHAQTKRILATKYPDYTIEISDEGY
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MARLYVGNLDPRTTARELEDEFRVFGVLRSVWVARKPPGFAFIDFDDRRDAQDAIRDLDGKHGWRVELSHNSSSSRGRDRHGGSDMKCYECGEPGHFARECRLRIGSGGLGSGRRRSRSRSRSRSPRYRRSPSYGRRSYSPRDRSPRQRSPSPRRRSYSKSPDDDRHRSESPHTNGYRRSRS
The following text describes a protein:
Function:
Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSESVLETERYAHEELERLQQAIVDRQVANPKAPRERLRLEHQSAQFLNQFRETSKKLLVSHESSDRLKDQEVARINADDDLTEFYKSLGEIQEFHKKYPDHKVEDLSQLYSIKPSQPGIDEIDTLFRGEEMYGRFMDLNECYEEYINLSNVQHISYLEYLKNLEDFDQIPKPEKNQTYINYITHLYEYLVSFYRRTHPLSNLDKIIAVFDTEFDAAWEAGLPGWYSHNAEAEKDGKDSTEAFYCEVCQKFFGKITVFEAHKKSKAHNKAVKRMQSSSPSTTSNTNEKQKGPKAIARIEFLIKKLTSLLDDVRKDTRENVVRRQTLTAAERLAEVEAAEREAFEQSTPSVSVEGNQDEESDQDDEEKIYNPLKLPLGWDGKPIPFWLWKLHGLGKEFPCEICGNYVYMGRKAFDKHFTEQRHIYGLKCLGISPSPLFNQITSIDEALQLWQKYKVDSKKRETTMASLNEMEDDEGNVMSEKVYNDLKAQGLL
The following text describes a protein:
Function:
Transcriptional repressor of genes involved in glucosamine transport and utilization. Represses the expression of the gamAP operon by binding to the gamA-gamR intergenic region.
Sequence:
MTALYSVIKFKIIELIKSGKYQANDQLPTESEFCEQYDVSRTTVRLALQQLELEGYIKRIQGKGTFVSAAKIQTPIPHKITSFAEQMRGLRSESKVLELVVIPADHSIAELLKMKENEPVNKLVRVRYAEGEPLQYHTSYIPWKAAPGLAQEECTGSLFELLRTKYNIEISRGTESIEPILTDETISGHLLTNVGAPAFLSESLTYDKNEEVVEYAQIITRGDRTKFTVEQSYHS
The following text describes a protein:
Function:
Interacts with OSBPL11 to function as lipid transfer proteins. Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex.
Sequence:
MEGPLSKWTNMVHGWQYRWFKIENDTLLYYTSREKMLKGQQRGQIRLTGAVVGIDGENNSLFTITVEGKTFHMQGRDLRERNQWVRILENSIRASSGYAKNVSVGTTPSQHFKQRTEEANEFLKTLVEKVKALEQLKSGERAVDEKKTIDSLIAASNNLTNNVKHAIIYLQMAQARLDPNMKTEKLMFTHPDLNEKPSSRETPGTVSDSTQTSTDKPISGIQHLDHLKPQRAESYASSDEEEFYDADEELIDLDNFESEKSGQESGDSNRTSDAAIMSSDEDGYDFGDSNEDFDEIYNNAEEHDIGNVQQDHGSVLMHLLSQVSVGMDLTKVTLPTFILERRSLLEMYADFFAHPDLFIATNGNDSAEKRMIAVVRYYLNSFYAARKSGVAKKPYNAILGETFRCRYSVPNSSLSGKKTESGPWPGSDEKQLTFIAEQVSHHPPISAFYAEMPSEGISFNAHIYTKSSFLGLSIGVASIGEGILTLHNYGDEQYTITFPSGYGRSIMSTPWFEFGGKVKVECEKTGYRADIEFLTKPFFGGKPHRIQGSICRDGAKKPVLTLRGEWNGTMYAKTQNGEEYVFVDVKAKPEVKKECVPVMQQGKRESRRLWRHVTAALLRNRIQTATTSKRFIEQRQRKEAKERLESGEKWTPLLFDTTDKDGEWMYKQKFGVRKAV
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
Sequence:
MEERTGIITFKGNPMTLLGPQLKVGDQAPAFTAVDTSLTVRSLSDFGAAIKIISAVPSLDTPVCDAETRRFNQEAASLPANVVLLTISLDLPFAQKRWCGAAGIDRVVTLSDYRDRSFGLAYGVLIKELMLLSRSVFVVDGNGVIRYLQHVPEVTSEPDYAAVLDSVRAML
The following text describes a protein:
Function:
Required as a cell surface receptor for peptidoglycan (PGN) elicitor signaling leading to innate immunity. Plays an essential role in detecting PGNs and restricting bacterial growth (of Pseudomonas syringae pv. tomato DC3000 for example).
Miscellaneous:
MISCELLANEOUS: [Isoform 1]: GPI-anchored form; MISCELLANEOUS: [Isoform 2]: May be due to a competing donor splice site. Has no GPI-anchor.
Subcellular Localization:
[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor; [Isoform 2]: Secreted.
Sequence:
MKIPEKPIFLIFVSLILASSLTFTATAKSTIEPCSSNDTCNALLGYTLYTDLKVSEVASLFQVDPISILLANAIDISYPDVENHILPSKLFLKIPITCSCVDGIRKSVSTHYKTRPSDNLGSIADSVYGGLVSAEQIQEANSVNDPSLLDVGTSLVIPLPCACFNGTDNSLPAVYLSYVVKEIDTLVGIARRYSTTITDLMNVNAMGAPDVSSGDILAVPLSACASKFPRYASDFGLIVPNGSYALAAGHCVQCSCALGSRNLYCEPASLAVSCSSMQCRNSNLMLGNITVQQTSAGCNVTTCDYNGIANGTILTMLTRSLQPRCPGPQQFAPLLAPPDTVPRDVMYAPAPSPDFDGPGSIASSPRSSMLPGGGILPGNPANGPAGSISTASASSVSYFFITFLISIASFSLALSS
The following text describes a protein:
Function:
Golgi membrane protein involved in vesicular trafficking.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
TSHPIALIFHVIFKTAALVTYMFSWLIVSDFILTFVIIILLLAFDFWTVKNVTGRLLVGLRWWNEIRDDGTNEWIFESRENRAVNTVDSRIFWMALYTAPILWVLLAILSILKLQASFFVVTLVAVSMSMANLVGYTQCEKVIVLFSRSMLRSMIKTLPLYLLTANRVYTIY
The following text describes a protein:
Function:
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
Sequence:
MTTPHTLLRSLPSDLDPNRLPRHVAAIMDGNGRWASKRNLPRVMGHQAGVSALKELLRCCKDWGIGALTVYAFSTENWKRPQYEVEFLMALFEKVLNHELSEMVDEGVRIRFVGALAHLPGALQSAIEGAMAATEANTAVEFTVATNYGGRQEIVNACRELAEQVRSGRLLPEQIDEKLFAQHLYTRELSDPDLLIRTSGEQRLSNYLLWQMAYTEIYVADVLWPDFDRAAFHAALQSYQGRQRRFGKV
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MPALAETLDGSSPFSQKEAVDDHALVSIAENANGSSPSSPLKALDDMASDSSLPNPTGSSPSVEEGQEDEPSPPSPLKIVGNDLSNYESDPHSESSGLSRWSSSAPSWSSRWSSNSTKESVISSDSQFSICETKPSMVGAGLANLGNTCFMNAILQCFTHTVPLVEGLHSCSHSMPCDRGSEGFCVLCALHDHVDLSVASSGRVISPWKLVDNLNHFSSFFQRYQQEDAHEFLQCFLDKLEKSCLDSLEKESPSAQDHNLVERVFGGRLLSKLRCCNCGHCSDTYEPLIDLSLEIEDAETLQRALESFTKIETINDLETKFTCENCKEEVSVEKQLVVDQAPPVAAFHLKRFKTDGSHVEKIEKHVEFPLELDLKPYTSGSDNNVELKYELYAIVEHVGFSSTSGHYFCFIRSSPDTWHRLDDSKVTRVQEEFVLSQEAYILFYARQGTPWFSSIVESLKPCLDPAMTNTSPKSVLENVESVSILSPSVNNVDCCVANEPGDAHERITLSLPRARCEEVEVIDTRDAADGCSKETKDSAAVIDASTPGRASNSFDGKSHNNENICSTSSLGGNRCHKRSPKVYLHPMTPPRSPSPDLPSFESPEPIYCLPRDHSKSVDNVACKRSLNNIIRSDHLKSADNALCKRPSNNDVDDSKRIEAFRYLSKKSLTRDRGSQLLAAMVGPQSEGSSNKRRKRVGSSPCKKVSPPGGSHKSMRPVAAALR
The following text describes a protein:
Function:
May play a role in membrane trafficking.
Miscellaneous:
MISCELLANEOUS: Present with 2630 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Traffics from the cell surface to intracellular vesicles near the vacuole. More enriched in the cortical endoplasmic reticulum (ER) that is closely apposed to the cell membrane than in the perinuclear ER or internal ER tubules that connect the nucleus to the cortical ER.
Domain:
The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers; The C2 domains show Ca(2+)-independent phospholipid binding. None of the C2 domains retains all 5 conserved Asp residues found in calcium-binding C2 domains.
Sequence:
MSPNSSKTRTDQISSMPGINEATKVESKNVVKDAVPIKSEVETNGTSIVREKQDPSYVGWKQVGGWEEKDELTSEDLLVDVNKDTFLGNLLPDKFYGDWYHEVAILIIAGLCSFVLGYFKFSLASVLIVMLTTGMLYRTSSKKYRESLRDLAQKEQTVEKITSDYESVEWLNTFLDKYWPIIEPSVSQQIVDGTNTALSENVAIPKFIKAIWLDQFTLGVKPPRIDAIKTFQNTKSDVVVMDVCLSFTPHDMSDLDAKQCRNYVNSNVVLKAKIFGMDIPVSVADIFFQVFVRFRFQLMTTLPLVETINIQLLEVPEVDFISRLLGNSVFNWEILAIPGLMRLIQKMAFKYLSPVLLPPFSLQLNIPQLLSKTGLPIGVLEIKVKNAHGLRKLVGMIKKTVDPYLTFELSGKIVGKTKVFKNSANPVWNESIYILLQSFTDPLTIAVYDKRETLSDKKMGTVIFNLNKLHANHYHKNEKVHFLRNSKPVGELTFDLRFFPTIEPKKLLNGDEEPLPDMNTGITKITIRELKGLDELSDKKFVFAELYVNAELVMTTKKEKRTAHLKWNSDYYSVVTDRRKTICRFVLKDQSGKVISSSVQPLNHLIDRTEVNKEWIPLRNGKGELKVTTYWRPVDIDLGLKSVGYTTPIGMLRVFINKAENLRNPDSLGKISPYAKVSVNGVARGRTNERIETLNPIWNQSIYVSVTSPLQKVSIDCFGIDTNGDDHNLGSLNIQTQNIYHKDNDDKYTIFIDNAPRTGNLIGKKGVKGTVTYYLSFYPVVPVLSLEEAKEVDEINEKKDKLEKQKSTLDDKNISKEEKERIKKEEFRLTEKYDMYSYKMKLDLDELLQYNAGVLGVTVLGGELPQPGLYVQTFFDSCGYAAITSAKNAIRTIKTGWSGDFMIKELEWSVTTFRVTKTKDANKAENFICEVNIPTIELVRNCYYKPSVLNLIGKKSAKLLVQVSWFPVTATELPQSDLITNSGDLKITAKSAENLIGVNKNGYSDPYVEFFLNEKSTSPFFKTAVQKKTLNPTWNESKTIEVSNRVNDYLTINVKDYESTNSNRSIGKAVVPLSTIDPESDTTFNIPLVGPKGEDGGVLHLEFEFEPRYTTNVVKREAGLGNFATKGLGTGIKAGSTVFALGTNVVSTGLGTIDKVKAGVFGGKKSTTTGDKKSEEKQ
The following text describes a protein:
Function:
Involved in transcription termination by RNA polymerase II and in regulation of Ty1 transposition.
Miscellaneous:
MISCELLANEOUS: Present with 3930 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MPFSSEQFTTKLNTLEDSQESISSASKWLLLQYRDAPKVAEMWKEYMLRPSVNTRRKLLGLYLMNHVVQQAKGQKIIQFQDSFGKVAAEVLGRINQEFPRDLKKKLSRVVNILKERNIFSKQVVNDIERSLKTESSPVEALVLPQKLKDFAKDYEKLVKMHHNVCAMKMRFDKSSDELDPSSSVYEENFKTISKIGNMAKDIINESILKRESGIHKLQSTLDDEKRHLDEEQNMLSEIEFVLSAKDPSRLNKNVDEDNIIPTYEVGDGDDDDDDGDNDDDDDDDDDDKNYDDRSNDSNYGVTNISTTDKKNEVVEKTDSEHKNSTHNPSDNQFGMKRTHDMIGHDDANDIPEKKVHLDSKTSEDGTFNSEDGHYELDIEGHVGAQTDEGVENSGGVSSSIQDLLSKLAN
The following text describes a protein:
Function:
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MVINNQNNNNQNNNQNNNNKNDNLNNSTTTTTTTATTTKSSTLFHSNDFFSGLIAGIVSRTLTAPLERIKILNQVEVILKDGTKYNRIIPAFKVIIKEEGIAGLFRGNFVNIIKAGPQSAIRFYSYGAFKRMASEPDGSISVINRMWAGASSGVVSVALTHPLDVIKTHITVIAPTAATIKNVTKGIYRDLGIIGFFRGLSAGILNIAPFAALNFTFYETIKEKTQQYILKSPPLYAPSIYGAISGGLTMTILYPLDVVKRRIMLQHFDRNQLPIYKNFIDAIIKITKTEGISALYKGIRPAYLKVIPTVSINFLIYEGAITLFEKK
The following text describes a protein:
Function:
Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MKLLIFAVIISVVLFPVLVSSRTIKCDQLSGKCINGEEKEIMNMRLGLDVSSRRILQASRYISYEALKKNLPDNRRGEPDQRDNPYRRSCDVHSHCYRFTN
The following text describes a protein:
Function:
Component of the Clr4 methyltransferase complex (ClrC) which contributes to the establishment of heterochromatin by specifically methylating histone H3 to form H3K9me. ClrC preferentially ubiquitylates H3K14 and ClrC-mediated H3 ubiquitination promotes clr4 methyltransferase activity for the methylation of H3K9. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting swi6/HP1 to methylated histones which leads to transcriptional silencing within centromeric heterochromatin, telomeric regions and at the silent mating-type loci. Has a role in both mitotic and meiotic chromosome segregation.
Subcellular Localization:
Cytoplasm. Nucleus. Chromosome.
Sequence:
MTNSSPRVKRRTDTQYLHSVSSKLPKVDFDTNNEEFFEEEFEIYDPFYRAELPCPKPSLSISKHSIAKVPSNVNKRLELQLLLTSGTFLPNSRPYLSERVRKHTHLLSNSITGDDKPSLIHVDFTPEECFILQEAKLKFGPVNSVQFNDAYSTHISPKLPGRAYEDCQKFEIDNPSLSPVDKHGAIILRTYKKNKKLLPDYLKSFYNAGSSYFQREQVHQLMDGESVFFLKPWKHFNETSGDTVCVAYNPLCEKFALGSTAQDGAYNRLGNLWIGDFHSETIQSLESHYKLNQVGEKEYSTISDLCFSKGNLFLYTGAFDNAVKVWDMEGNLCGIFNAPTDYIHKLALSDDDLLAVACKNGYGYLLSTDNSTGEILTSANLIYPEALEKGYSASLIEFSNFLGRSSDKVIIGYDSFHTSNNRGCLALFDASTASFVQKFNTADEAFTSLYMHPSQVGFVASSNTLSNGRVYYLDTRMYKVCLNFTTTQKDINHATISNSGILVTSSGTDNQTFVWDSRKPDKPLSLLKHGKTKMIHFDGANEEEVDAGINMAQWQPKGNLFVTGGSDGIVKVWDLRLNNPFIQNFTEMNSAITYGGFSEDASKLTVCCVGGDVNMYSLGNDNGNKFGEFRIIENRLLT
The following text describes a protein:
Function:
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for energy coupling to the transport system. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI).
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MIELKHVTFGYNKKQMVLQDINITIPDGENVGILGESGCGKSTLASLVLGLFKPVKGEIYLSDNAVLPIFQHPLTSFNPDWTIETSLKEALYYYRGLTDNTAQDQLLLQHLSTFELNAQLLTKLPSEVSGGQLQRFNVMRSLLAQPRVLICDEITSNLDVIAEQNVINILKAQTITNLNHFIVISHDLSVLQRLVNRIIVLKDGMIVDDFAIEELFNVDRHPYTKELVQAFSY
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MAVAKSKAGKHAAPLLGKYELGRLLGRGTFAKVYHARSLVGGEAVAIKVLDKPGLAATAGMDARVLGEVSAMRRLRHPNVLRLHEVLATRSKVYLVMELAPGGDLLSRLASLPSRRLPEHAARRVFLQLVSALIYCHARGVSHRDVKPQNVLLDADGNLKVCDFGLAALPESHRDDGRLHTACGTPAFAAPEVLRRKAYDGVKADAWSCGVILFVLLAGRLPFDDSNMADMCRKAHRREYTLPEWVSQPARRLVSRLLDPNPATRLTVAELSTHPWFKRSLSLDSQLGSLLGGAPERDLLFQAPPTLNAFDIISMSPGLDLSGLFGENRRSREKRFMTTASPEQMVEQLGHSGAKLGYFMVGKKGVERLPLGGLSGLVAMSMEMSEVAPPLMLVELRLEAGDDEEVEKFGWDELRTELGEVVMAWHGCEEL
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSNEHNPLQLGERSHQQHPEHHHNRRGQGYRHNNRGRGRGNQKTNPEQSEVDALFSKAFTFQKTEPPWTLPNKENLFFSPESASPDDWNEGLSDLRSKLRLTQERLSDKEILEWHTHTGSTHRGGLVITELKKRFHIELGTQAWSKFHEILATRHLIPDSALNSGTLHSLHICEAPGAFISSLNHYIKTHKDKEIIQWKWLGTSLNPHCETNTADCTIVDDRLILQTPDCWYFGDDNTGDVMSAANLAGLERLIQQEMNGTVHLVTADGSVNCQDDPEHQEHRVFPLVFCQSLTALKLLAPEGAFLVKMFTMYNANTACLMNLLNIAFKEVTVLKPACSKAGNSEVYVMCKSYLGRDHLQPQLDTLLQHFGPDVGKTPLFSPAHLPESFVTQLEKCSLKFTNYQVAAIEENLQLYPNMDPSSRQRIDRVRAQCVEMFIKRCRLRVARKHQKLMPNYGSKACSMFKKNMWHRLHGSLDDRGEVGHRSWKEHLQSILRDLQQQGYKAGLGGDSQRGSSPKKMRSSVSVSDQLDSSELEGGDSHQTNAGDARLGGGGDGLGLGSGPGPENTGPTIQAIHCDQPSSAVRCHGDGGHVGRHESAMEVCDHEQRTLNPVQTSSVQASVGVAGIVGDVAAMDVGSPETTPTISTTSLQECAWSHLAEDASVRVSHSDYSRIAKTVCALCIHSKMELSEDPNVGGEKQHVLDGAVGGQRSTTNETTEGRSSEIFTVQIPWITPGKHDLDSLGSWKIVTGHPVRAVFMSPFCQMPLLDKWRSVRTNAQVLQQSTGHNVKGHPQCDLSPQIYEVIEGLLSKRPVPSSGQEESWCCSGVNKQELDLLDQLASTHNAVIKSCRDNNPRGEMFGDIQHLLEREADGKRRFKSFFFKLLPSCIARETEPTAGELETKQDFISACLLAIKELQAGGSLHIWVPGLLTRFSACIVYILSQAFDLLTLVRGQRSDVLTAPRVLINCAGFHPNPQIEQNFQRVYERMKELHQGGSHDVLRFIPMLSLFNPDFDKAITRFNENLIREDLLHIVKAELALLDDSDDAGLLDNMSSEIVYC