lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Thiol protease that seems to be involved in the sexual development.
Subcellular Localization:
Secreted.
Sequence:
MKLILVLLCLISTLFVVKGGLSPTEQQIIVSYHNKWRSSPIGPTPSTTIPALKWNATIAAALQSSLDKCDGKFSTMSQYGTNSEWQSWWTPNTYFNLNATLDNIQKGASFYDWNAKGCNSSANYNCQLWTYAVWSKSTSYGCAKTICPDKSEVSCSYYPAGGFKGVLPYTPKTTTPAPTTPAPTTPKPTTPAPTTPKPTTPAPTTPKPTTPAPTTPKPTTPAPTTPKPTTPAPTTPAPTSTLTVDWTSYQTPIRDQGQCGSCWAFASSAALESRYLIKYGTAQKSTLQLSNQNAVNCIASGCNGGWSGNYFNFFKTPGIAYEKDDPYKAVTGTSCITTSSVARFKYTNYGYTEKTKAALLAELKKGPVTIAVYVDSAFQNYKSGIYNSATKYTGINHLVLLVGYDQATDAYKIKNSWGSWWGESGYMRITASNDNLAIFAYNSYYPTF
The following text describes a protein:
Function:
Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.
Subcellular Localization:
Virion. Virion tegument. Host cytoplasm. Host Golgi apparatus.
Sequence:
MEALMIRGVLEVHTDFTRQNVMIMEPQVLDFTVRGDKLWLHTEHGLLVSMAEYRSELLCTSAFLGYSAVFLLETEDAVTQVRLSDLRLKHRCGIVKADNLLHFALCTVISCVENCNLTRKCLHDLLQYLDAVNVRESFGRLLHHSARRLICSALYLLFEEKEPHIVQYVPATFVLFQQTRHTCLQLVARFFFRLTGQDEAHSFSLKLTERKTVDGWPVGLGLLDVLNANYPNLPSPPKLPPRWERGEEE
The following text describes a protein:
Function:
Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.
Sequence:
MYTIAVVGLGGSGCEVIRSLMHAFNTASISSDQVKLLIVDRDTISETNLGKQALYNGESVGEFKSSVACAFIEGQGYRAEAYSTDAARPAFVTKLATAAMTFLCVDNVEARRKIIPALLLAQKTVIDVGSEGLAGSIRLYSSQYPCFYCTSWMYPKRKRPLCSVPGIPRTAEDCILIAAYALSESNGNDPQSEESYEAAVLSRANELGEIHNLGLQIAPGDVTNALQQVVSTPFHISGLVASYAVSLWCKYFMGSLDRRTSGTGGLPRNAWPQECLWMISTYNGLYIRAFTLERQKDCSCTFSLPSSSPDRSYSSVVSEYINAPDFTIVADQRIVYSRLLLPGPAAAMPLEKDLEGAIFVYANEKLVYAEWLDYKLPLSV
The following text describes a protein:
Function:
Transporter protein required for ammonia export. Induced in rho(0) cells, probably to eliminate the excess ammonia that arises because of a potential defect in ammonia assimilation in those cells.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Localizes to large detergent resistant patches of the cell membrane (DRM) enriched in ergosterol and sphingolipids.
Sequence:
MTSSASSPQDLEKGVNTLENIETLPQQGSIAGVSQGFPNIQEIYSDRDFITLGSSTYRRRDLLNALDRGDGEEGNCAKYTPHQFANPVPLGLASFSLSCLVLSLINANVRGVTDGKWALSLFMFFGGAIELFAGLLCFVIGDTYAMTVFSSFGGFWICYGYGLTDTDNLVSGYTDPTMLNNVIGFFLAGWTVFTFLMLMCTLKSTWGLFLLLTFLDLTFLLLCIGTFIDNNNLKMAGGYFGILSSCCGWYSLYCSVVSPSNSYLAFRAHTMPNAP
The following text describes a protein:
Function:
Involved in cytokinesis and septation where it has a role in the localization of F-actin.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MFRKDRTRSQRGNGIPESLIPAELADVIYNQRAFEEHCAAMVKLSKKYEDTITELGRERVRLREELLSMPIFTTRQDDSTPERLNFDERIDQFRKVTDFLAERGKDLHDNYHGAVNDPLKRFMKMFPAINEKVKQHERCALDYVKAKERYDRTLHSSQADQAKRDKAASQCDAALNAFNNVNELVPEELPLIHAARFDFLDPSCMTMVAAHIRYLEAVVDNLSAICHEHEVKMSDEDYNREIEDIFSKLSALRITADGLDATVA
The following text describes a protein:
Function:
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
Subcellular Localization:
Cytoplasm.
Sequence:
MCCTSGCALTIRLLGRTEIRRLAKELDFRPRKSLGQNFVHDANTVRRVVAASGVSRSDLVLEVGPGLGSLTLALLDRGATVTAVEIDPLLASRLQQTVAEHSHSEVHRLTVVNRDVLALRREDLAAAPTAVVANLPYNVAVPALLHLLVEFPSIRVVTVMVQAEVAERLAAEPGSKEYGVPSVKLRFFGRVRRCGMVSPTVFWPIPRVYSGLVRIDRYETSPWPTDDAFRRRVFELVDIAFAQRRKTSRNAFVQWAGSGSESANRLLAASIDPARRGETLSIDDFVRLLRRSGGSDEATSTGRDARAPDISGHASAS
The following text describes a protein:
Function:
Probably involved in the defense reaction of plants against pathogens.
Sequence:
MAIYCSVIVLNIHDVHINHVEKVTAKSNANPHANNVDDDGNGIGTSIGGIANVANDIVNGIANALKPNNENYTEYPPPALAQEFIMVHNEIRKAENVPPLVWNETLAQFAEDWAKKQTDCGMRHSKGQYGENLFWGFKAHWLPREAVEDWAHEKQFYNREKRQCAQDKACGHYTQIVWKTTQQVGCARFRCSNGSLLIICEYAPPGNYANEDPFNPGSPLSPPPTPSATSPPSLSSPSSPSPPPPTPTPTPPLPL
The following text describes a protein:
Function:
Has antibacterial activity against the Gram positive bacterium L.lactis.
Subcellular Localization:
Secreted.
Sequence:
GLLDVVKGAAKNLLASALDKLKCKVTGC
The following text describes a protein:
Function:
Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MPPPAEVTDPSHAPAVLHQLNEQRLRGLFCDVTLIAGDTKFPAHRSVLAASSPFFREALLAQAPSPLPPVTRDPAPNPSTSSASSSSSSSSSSSSSSSFSSSSSSSFSSSSSSSSSPPPLSSSPTVSHPPRVLELPGVPAAAFSDVLNFIYSARLALPGGGGDGAAMAEIGALGRRLGISRLQGLSESGDAWVPPAPAPPAPVEIDSFTTGPSKEWQGSGNEVSTVQTSLPRRSLPCPRCGKSFIHAKRLQTHEAQCRRGTGTRGTVSGQGNGGSQEENPEGIRNSSASPSTSFRGGPEHVVKVVGGHVLYVCGACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRYQCIFCWETFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPKLNTLKLYRLLPMRSAKRPYKTYSQGAPPAPVSAPLSPEPTPSASTIPPLLPTTPPPPPVPPPPPTPAPPPSVIAFAHPAPSVIVHGGSSTGSGMTGTTGAQAASVIAYTAPPRPPKKREYPPPPPQPAVAVVTATPSTPATTTTGATAEETKGRNLRAGKTLTYTAKPAGSGGVGPSGGLSWGGDSSQPQPPPPLCQITVRIGEEAIVTRRISETDLHPGEASGLEEGDDSEDEEEEEEEEEEEEEETEAGSEDQLWRPYYSYKPKRKLVGTGGGSSGTNSNSGTPKCRRPRWRRKLERRAWEESRSTESPSGQSSSEWKHQCGDCGKAFSALRKLRKHQEAHSGGGTQGPRAGRKPLTRFACSHCSKVCKTAAALSRHGQRHIGEQPGGTPTPVIAYSKSSGGSGTGSGLGLGDSGVKEEAPQEMQVSSSSGEAGGGGGVGGGGPEAASLQDPVISGGEEPPAVGSGDYPPVQEFPLALVEDKQEVLGGGEKVGAEGLVGGSVEETAAAKVTFYPEPYPLVYGPQLLAAYPYNFSNLAALPVALNMVLPDEKGGGALPFLPGVFSYAVNPRVAPPTPPLPQSMPSPVPPKGDGGGEGIERAQKGDVG
The following text describes a protein:
Function:
Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
Subcellular Localization:
Cell membrane, sarcolemma; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAAFVLLFLGGLALLLFSLPRMPQNPWESCMDAEPEH
The following text describes a protein:
Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.
Subcellular Localization:
Mitochondrion. Mitochondrion inner membrane.
Sequence:
MLQQVLRIGSQARPALTVIVRRNLGASSVVMAKTKAAAGPTDPVQKLFVDKIRDYSNKKKSAGGKLVDSDPQTEKEMATEIGKLNKMFGGGDMTQFPTFEFKDIDFGAEEKK
The following text describes a protein:
Function:
Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.
Subcellular Localization:
Nucleus.
Sequence:
MSLYDGIDLEEKQKADLAGWGSSLKLLETQKQLQEKKMMLQSLNKKKNNPTLTPVISLKNRRGEDGHNQVESMGGLFGSYIGDVAFVGIVDEYDPMKPNDYEKIVKSKKQNSNDDDRSRHDDHHRSSIRNDEDDGYKHRPPGWRNGPLLDDRKRRDRSRRDEDDYDSGSAAKIRKSESESSMAPKAAIAPPPSLIEADDKKIVDFQGPVLNKPEPPGSQFGLSGSVASKIMARMGYKEGQGLGKQEQGMSIALQVEKTSKKIGKIIHEKDLHKSQDLSVPRAEMSNANLLRNPSKVIMLQNMVAPGDVDDMLETEVSEECAKYGKVVKCVIFEIPDAIEEEAVRIFVEFDRLEASIKAVVDLNGRFFGGRVVKGNFYNIDKFKQYQLGDDVD
The following text describes a protein:
Function:
RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.
Subcellular Localization:
Nucleus speckle. Nucleus, nucleolus.
Sequence:
MRERSRGGTRMRGVGGGAGGGGGGGGCRARRGARVRERATGPHQEARAGGGEVLLARASAARWSKGSRMQVKSSAPVTMVRERKCILCHTVYSSKKEMDEHVRSMLHHRELENLKGRDSDHECRVCRVTVVGLSAYAKHISSQLHKDNVDAQEREEDGKEEEVEEEYFDKELVQLIKQRNEQSRQDEASVTVQEINSDDRRQWRREDRGAYQERDAYDQPSWHHRVPLQRDWKWEKDGFNGGRKNNFPHSLRNGGGPRGRSGWHKGGPGGSSNWYHNHNNSGGSWHPNNGTVDWHHGGTGRNSSWHSEGTDGFWHMNNSSGNWQSKARGTNSWNYSVPGDIFQPGRNRNSNCQIDDMTMLWNKKSNKLNKYNQGRYTWQRQENRGPTEDDNDYLLDFTSDKLPSEGLLDFSTSEQPESQTSKQAEIIAPKMSGKSGNVSKDKIHRWTPYPSQKIVEPQQPGLKEVTAKKSEVVDEPPFLFHLITACGKDLKTNNTDNSTKLKTQKETQLGSFDHKVTSNHTVSNEAVTTCTSRVIPEQENSSHKMPSLKSPLLPIPNTRSSSQKQDSKNLLKSTKPLSATSGECQNHSNTLSLEDNQNSSYVSKLRSSCSRVLKGNKTVLDGTQREPVDNLSEVLKKAKEVLKCSQPLQNPLLSNAKSIRSCASESKNGEESVKSSLNTELQECAPEDRDEAELSDLEKHGTKVEDLGPLNPKGSPCGALECEHPVTEKERDDKTIKTTEKCSINSDGATVQHKESEFQMESAASAASPQTGLLLDFKTSLEDIQVEEPVKSGLPFETESFDNSNLDVDLQKGGTGQPSVSLLPELSKLGFPASLQRDLTRHISLKSKPGAHLPEPNLNNARRIRNVSGHRKSETEKESGLKPTLRQILNASRRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEVLDLDEEPDLSSLEGFQWEGISIATSPALARKRSLSESSVIMDRTPSMYNFFTEQATGKENEPQQIVSPSNSLQTTQGQKANVNFKQDMMPLASSSRAGEKVESVATRRRHSAQLPPDRMISLVRSARQEELNRQESSTPLSENQNTQESNGEGNSLSSNASSGLGISSLVDAATDSSCTSGTEQNDGQGLRKKRRATGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLNISLREEELSKSLQCMDNNLLQARAALQAAFVEVQRLLVLKQQITMEMSGLRTHRIQILQGLQETYEPPERTEQVPCSPSRERKSRSQTAADPPPLPSPFFPLFLETPPSHLSPSAPGVPLRVCTPPAFQAPGSITCPAPDSSVQIKQEPMSPEQENVNAVLQDSACSASEELLQTNREISGNYSLYPIIAGTLSLSHLTESFQHASQEMKSSLEQGGTRRVEQSQLIGPLIIKKEGEVSTKSSTIGEPCSSSFLSLTFPSHTPLEKGHPLLVEQPAESTLTSVENKGNKKKKKLRKKKTLRATHVPENSDTEQDVFTAKPVRKVKAGKMTKGGKVTTSTSLGQEDGKTGQEQDRNRDEPDSDSSLEVLEIPNPQFEVVAIESSESGEEKPDSPCKDDTWNSTDQSLLEASRSGCDEVSSTSEIGTHYKDGIPRSVAETQTSISSIKGSKNSSEISSEPGDDEEPTEGNFEGHQAAVNAIQIFGNLLYTCSADKTVRAYNLVTRKCVGVFEGHTSKVNCLVITQTNGKNSALYTGSSDHTIHCYNIKTRMCLEKLQLEDRVLCLHNRWRILYAGLANGTVVTFSLKTNKQLDIFECHGPRAVSCLATAQEGARRLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQAVKLNLMQNFRCWWHGCSLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDAFFTARKGSKQDAAGHIERHAEDDSRIDS
The following text describes a protein:
Function:
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
Sequence:
MRCARRHQSRQHLARTALSVALTVLLIATTAAAAAVAAAASSSASSSTSVPPTEQGDATDTMQNLSTHILDTTRGKPAPEVPVTLYVRAASQSWTKVSTGITDGDGRFRSFFADGQPGLAAGVYKLHFDVGPYFRSRSVESLYPFIEIVFTVADPTQHYHIPLLLNPFGYSTYRGS
The following text describes a protein:
Function:
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNSTNSSNMNETEGWTKSTFLYDDPITALLIVAYGLVFLLCIIGNSVVCVVIIRTARLRTVTNYFILNLAVSDLLVGIFCLPFTLAYHIFNDFQFDDAMCKLTPFVQGVSVAASVFTFLMIAFDRYKAIVFPTEPRMTLKAMRKTLVGVWICALAISTPQIFVNNIEVYREGSESLHVCYEQWPDVVYKQTYTVMLLTVVYIVPLLSVLYLYGRIFHRMMFKPGPRTGGNLAANRNKCTGAVSKKRVRVIKMLITVVVLFAMSWLPLYTVWMLLDFGNLPKETDAFIHVNVFPFVHWFALSNSCVNPIVYGLFNSNIRKHIRSALSLKDSNGHSNKTDGLRIATLSPEEGKTSRSTTPTMRTRQTVLVEETRL
The following text describes a protein:
Function:
Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Very weak inhibitor of the endogenous nicotinic acetylcholine receptors (nAChR) in the human rhabdomyosarcoma TE 671 cell line. Not toxic to mice by intraperitoneal injection or to zebrafish by injection at the back of the dorsolateral region.
Subcellular Localization:
Secreted.
Sequence:
LTCHTCPYNTCANSETCPAGKNICYQKKWEEHQGERIERRCVANCPKLGSNDKSLLCCRRDDCN
The following text describes a protein:
Function:
Sesquiterpene synthase involved in germacrene A biosynthesis. Germacrene A is a precursor of several sesquiterpene lactones.
Sequence:
MAAVGASATPLTNTKSTAEPVRPVANFPPSVWGDLFLSFSLDKSIMEEYAEAMEEPKEQVRRLILDPTMDSNKKLSLIYTVHRLGLTYMFLKEIEAQLDRLFKEFNLEDYVELDLYTISINFQAFRHLGYKLPCDVFNKFKNDDSTTFKESITGDVRGMLGLYESAQLRLKGENILDEASAFAETKLKSLVNTLEGSLAQQVKQSLRRPFHQGMPMVEARLYFSNYQEECSAHDSILKLAKLHFNYLQLQQKEELRIVSQWWKDMRFQETTPYIRDRVPEIYLWILGLYFEPRYSLARIIATKITLFLVVLDDTYDAYATIEEIRLLTDAINRWDISAMNQIPEYIRPFYKILLDEYAELEKQLAKEGRANSVIASKEAFQDIARGYLEEAEWTNSGYVASFPEYMKNGLITSAYNVISKSALVGMGEIVSEDALVWYESHPQILQASELISRLQDDVMTYQFERERGQSATGVDSYIKTYGVSEKVAIDELKKMIENAWKEINEGCLKPREVSMDLLAPILNLARMIDVVYRYDDGFTFPGKTLKEYITLLFVGSSPM
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Subcellular Localization:
Mitochondrion.
Sequence:
MIRKLFSKTLPFIRPQFYINHIFDTQDQFKKFNRSSIESIKSSVNPLPSPSEEARLYMEENEVDVRFLKVLKSFDKIDVKQINWEGDLNKDLGLDSLERIALITSIEHEFTAIFEDRVFDNLKSLQDIKNQILKDDSAF
The following text describes a protein:
Function:
Not known, binds calmodulin.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSCFCSVQEEFYCEVLLLDESKLILTTQQQGIKKSTRGSVVLDYVFSHVNLAETEYFGVRYCDRSHQTFWLDPSKTLAEHKDLIATGPPYTLYFGVKFYAEDPGKLKEEITRYQFFLQVKQDVLQGRLPCAFNISAQLAALAIQSELGDYDPYKHTAGYVSEYRFVPDQKEDLEDSIEQIHKTLLGQVPAEAENNYLAIAKTLEMYGVDLHPVFGEKQAEYFLGLTPVGVVVYKNKTQVGKYFWPRITKVYFKETQFELRVLGRDCNETSFFFDAASKTACKNLWKCCVEHHTFFRMPENESNSLTRKLSKFSSLGSKHRYSGKTAMQIGRESTETLPRADLQVIRTRSKTYPKRSTQPAGRNNGGQAVTKMENTSEGQPKTSALTPVKSPRVKAESASVQQEKPSAPWEEDAPQSGLYNSASERNKSPKFPKAHRRSPSGGSENEPRHRRGQTADDAQANKQHRRRSRSRGNTSSGSESENSNREHRKKRNRSRQSNEMVDSAPQWEVVLRRQKEKTPNDPNQRRSRHRSRSRSPDVQAKEQLWKHIQKELVDPSGLSEEQLKEIPYKKVETQGDPIKIRHSHSPRSFGSTGAPTARTERGLCCPKSTLALIWFLLWL
The following text describes a protein:
Function:
Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Subcellular Localization:
Mitochondrion.
Sequence:
MANVRCLYKLIRLQKLLLPLNATSSRLAPLQPRPLTFLIARSYGKDEKKANLEDFRAREEQRERERDAADQAAEKASQKEAGGGGGLGAKGSESTGPEDDAKQAKVDAIRAKILDAALQHVPQQGWTRQAIILGAEESGYPSVVHGMFPEGGFALVSHFNGKCNAQLVESLQQKTDGGKQEVEDPLDFLVQAVRQRLEMVTPYKTHWPQAMALLAQPQHAPTALAQVLTLVDDICYYSGDRSVDFGWYTRRVGLATIMKMTELYFLQDKSPGHAQTWEFLKSRMDEAVQLQMMLSQTEGMTHTFQRSFNSAFITARNILGLGYNRN
The following text describes a protein:
Function:
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
Sequence:
MEINYELYLITDRRFLKGRQLKKVVEDAILGGVTIVQVREKDVSTREFYNVAKEVKEVTDYYKVPIIINDRLDIAQAIDASGVHLGQKDMHLNIAREILGKDKIIGISVGNVKEALQAQNNGADYLGIGTIFPTGSKKDVDAIIGIDGLSKIKDSISIPSVAIGGINKTNFKDVLKTGIEGISVISAILDEDDIKLAANNLLINK
The following text describes a protein:
Function:
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
Subcellular Localization:
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Note=May associate with the mitochondrion outer membrane.
Sequence:
MRVKLCGAAGGRLGTLAGLGRSGAAALALPGCLLYTRTGTAPHLTLDTLREVSGVPPVAQLTLPAMAELHDVLAEYKEGAAKFIGMPDTVLYCSLQDPVAPCPSGYNTNKTVSLWSSSGRMEMTASKFMDIQRAIQPDWFQCIADGDTISGEVTRKRAKKSVDRSLSFLDACLQLLEKTPELQGSVMFGTIEGGDVLEERLRSARETAKRPVGGFLLDGFQGRAMAKETKMNLISSVTAELPEDKPRIIHGVGKPDEVLECIERGVDIFESFFPFQVTERGCALVFGYDYLSDPKAEAALKQNGAQDLEKNSPEEDQEEEVVKADPEMTPFEIFLKEKRYHDDFRPLLEGCTCYCCQRHTRAYLHHLLVSSELLAGVLLMMHNFQHYFSFFSAIRDALRDDKLDQLKKLIFRQALQGPENAKIDQ
The following text describes a protein:
Function:
Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MAADDRYRSDAAKVKRKEQLNRWMGSETERCGGPGVSRRAARVRFAQGAVFMAACSAGDRDEVRELLAAGAPINGTNVDGLTALHQACIDENIEMVQFLVENGSNVNQPDNEGWTPLHAAASCGFVSIAQFLITNGASVAAVNSEGELPLDVSHESAMEKLLKSEVKKQGVDADVARREEEEVMLRDVRHWLNCGKAEDVRHPTTGATTLHVASAKGYNEVIRLLLQLGFDVDARDFDGWTPLHAAAHWGQEEACRLLVEALCDMEIINKVGQTAMDVADDSLESVLEKLKDKQSVLRLEKKKMAPQIMNQTSLNQNAANKSRRSSISRMSSQEKVALRVQDKERRAQPPPPVGLPSIPTAVGSDAESGSDTESQKVKAQERINNLNNQLRNLPEPAAKKTSSLQDQEKSEPASGSWRASLRKTGSTGALSTGTAPEEGRRAALPKSASSSQLSEREKAGSELRLARVPPNQKLFSNQENARDTVLGQRSYLRQRTDGEDSISSLRRQRGETLANKTENSIPRRELLTPKPEAPVPNKTPIAAKEENQISTPDALGRRTGTTNAITTNTVPVVNTETKERRRSYLTPVRDEEAEAQRKARSRHARQSRRSTQGVTLTDLKEAEKVMKGQQDNKEAEATPEPVKAQEEETNRESQVKARTGRGASEEGTEVSWRARIASLQKSDLLGLTTPDSAPTSSGSHRRTTGGQSLESKEMQKSQEDEKESDEKGGKNKAGVKDRRRPRGKRRSTGVPLTTRDSDEEDSEDEEGNGESTQTQVDGLVSRADSRFHTRTTVQGEPSLASEYRDTRDFKKLYEELMRDNGRLRSQLLNTQNLVNETKAELERAQQRQERSVDRSFLIDTEKKEKVILERRLSELQEELKVLGDLKADNQRLKDENGALIRVISKLSK
The following text describes a protein:
Function:
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLSRAGQSILRQARTQLRPQAGPTPVASLSALARLLSSLAVLEQREGKLNHGSLGAVTAAQKLGGSITAFIAGSNIKSVAEEAAKVAGIEKIIAIDNAAYDKGLPENYAPLLVENIKKGGFTHIIAGHTAFGKNLMPRVAALLDVQQVSDITGIENEKTFVRLIYAGNAIATVESSDEIKIITIRGTAFAAAAAEGGSASIEDGVDPKVESQTEWVSEDLAKSDRPDLATAVYRSAKPERHLRCYSTFGRYEGQ
The following text describes a protein:
Function:
Major facilitator superfamily transporter that may be involved in A.fumigatus adaptation to azoles such as vorizonazole.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTSNKKSRLPPYQPGEHVSPSVHLNCVLLTTTVVNFLDLFQLSSVLFALPNIQQALGFASEDINWVLIVYNITFAAFLLIAGQLGQRFGLEKIFIAGTATLTISNVINTTAPNKGALLAGRAISGVGAGLTAPNGLAILSNTFPDPESRNKALAIYTACGPLGSTIGTVVGSHLACMSGWRSIFWLCLILTGLSTILACLFLPRFAKRKDMPIDIPGTVVFTAGVALLVYGLNDSSRRGWTSAAMLTGIILGVCLLFVFLWVEAKVSNPAISSYLWKSGPFLVMLVAIFAFGGSFSTWFFISTQLCVNLLGYSTILTAVYFLPAAFAAIASGVFATPLIRLAGEKNILVAGLAITAAGAVAWAFAGPRIGPAVPTTGRDTAIIFVIGSPVALVPTQSILLREVEAGNHAVAGALFNTAYQVGASVILAGANALMDRSRANVQGVRQVTIDGYLNAFWLIAGVLGAAALTVMVCYWPGKDDLVERQTEEANAVGPLAVDKVDTSKDATASARSVADTRL
The following text describes a protein:
Function:
Motor-binding component of the dynactin complex which assists cytoplasmic dynein by increasing its processivity and by regulation of its cargo binding (By similarity). The dynactin complex is required for the spindle translocation late in anaphase and is involved in a cell wall synthesis checkpoint.
Miscellaneous:
MISCELLANEOUS: Present with 238 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to spindle poles throughout the cell cycle.
Sequence:
MRNAGVQVDTNMQKISLQDTVLVNEMKGRVKFIGETQFAKGIWYGIELDKPLGKNDGSANGIRYFDIDLKKANSNGGYYGLFCKKDTLQFYKPDDDEHSLLNGNAAQETIKNLQVKCESLASKLNKIKIENHELKTSVEKLSTNETVLLSKISRLDKLVKELKVENGNMKTHLDNFNHLLDASDSVMAPDLDKGTLLERSHLLQGLLDQTKLSYDKAMKVQEDLLEENTQLLEENAVLSKKISDLGLQLQQTNNTIGDLALQIEAQSKSSNIVDKLTNDNILLTSNIKALNNELEELQAKEKLDENLRITYEQLEQELRLQLSNLQSALENEKEIAGTYIEENSRLKATLESIEAKTSHKFQSLELKVNTLQEELYQNKLLKKFYQIYEPFAQPHLAALSSQLQYLAEVIESENFGKLENIEIHIILKVLSSISYALHIYTIKNTPDHLETTLQCFKVNIAPISMWLSEFLQRKFSSKQETAFSICQFLEDNKFLDKDVTLILKILHPILETTVPKLLAFLRTNSNFNDNDTLCLIGSLYERSLSLIARIDKLIGKEEISKQDNRLFLYPSCDITLSSILTILFSDALFLRQDYKRISSLKKLEVFFQGIESLLENITIFPEQPSQQTSDSESQCNIKEGNFSNSLLSDRLNEENIRLKEVLVQKENMLTELETKIKIIIGRDLERKTLEENIKTLKVELNNKNEENCGKTEILNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKIYLDREKVDRVNLVSEIMELRETIRRQIKEQKRVSIDFSWLDELPAVENKQPFKEHINHSLDTLGIEMFNFVSTSRILDLKLDQPLAEDELWHERDHSYISYLKRKRKNIRLKSQNVVTYYK
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Miscellaneous:
MISCELLANEOUS: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
Sequence:
MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTPGCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDEDHQVCEQFGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA
The following text describes a protein:
Function:
Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLTVNLFYLLLHFVYLDPASPLQTDACKLCDCSGVELKCPQQTTGTRTPALELLFSHFCFKIIPSEVFQHFQQDIIRITISESNSLERIQSYAFSNLSSLTELTIQNTKNLIHIGEGAFGNLPTLKYLSIGNTGIRKFPDVTKIFSSQLQFILEIYDNLHITTIPANAFQEMNNEPLILKLYRNGFEDIQSYAFNGTKLDQLFLNNNNNLQYIHNDALKGASGPNRLDITSTALEYLPSYGLEFIQVLVAEYSYYLKQLPALDKLDSLIDARLTYPSHCCAFRNMRLKEQNALLENLTKQCDSTLHKQFNGTNSNEIPSNLPLWTEKEKNLTAMFFDHDEADLIADYEYLCQPKILKCSPEPDAFNPCEDIMGYDFLRVLIWFISILAIAGNAVVLFILLTSHCKLTVPRFLMCNLSFADFCMGIYLLLIASVDSQTKSKYYNHAIDWQTGSGCSAAGFFTVFASELSVYTLTVITLERWHTITYAMQLDRKLRLRHAILIMLGGWIFSLVIAMLPLVGVSNYIKVSICLPMDIETPLSQAYIIFILVLNVIAFIIICACYIKIYIAVQNPELAPTNKDTKLAKKMAVLIFTDFTCMAPISFFAISAAFKVPLITVTNSKILLVLFYPVNSCANPFLYAIFTKAFRRDFFLLMSRFGCCKTQAELYRVNNFTAYTSNLKMDSLYTGPKKTSRAEFHVMAPDCQQLNDHEKPASTGS
The following text describes a protein:
Function:
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MEGPLSVFGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYISENLIINTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAVKYTDLRGQPRYPVNSVNILKAHGRSQVESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIEKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGASILSTLANLEGEETFEATMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLINGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPETKDDKHGSYENAVHSGALDD
The following text describes a protein:
Function:
Multidrug efflux pump.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTDISMRFGMQAEAREFLKLAVPLAGAQMAQAATGFVDTVMMGWLGQDVLAAGGLATMIFMAFMMTGVGLISGVSPLVAEAYGAGQTRRIGQLTRQGLWIVLLLSIPGMLFITHLNGVMHWSGQADTTIILSDSYLNVMAWGLFPAIAFATLRGCIIALSQARPIMLIVIAATLFNILGNYGLGFGKWGFPALGITGLAIASISAHWIMFLSLLVYMLWHKPLHQYSLFDSLHHLKPRILQQLLWVGGPIGIAAVLEYGLYLTASFFMGALGTPILAAHQVVSQTVLVLFMVPLAMSYAATVRVGQWFGQQHWPQIRQAALVSIGLAVLFMLTAGIALLAYPQQIIGLYLDLNDPANGEALNVGISIMKIAAFGLVLDGLQRTANGVLQGLQDTRIPMVLGTIAYWGIGLTASYLLGFYTPLSGAGVWIGTYIGLAAASIAYLWRFQKVMVRKKSLPVARS
The following text describes a protein:
Function:
Plays an important role in the elongation step of protein synthesis.
Sequence:
MLAAVGAEGEDDRIQLVLSEVKGKDITELIASSKEKLASVPFGGVGNPAIASISKVEFLDVLSQIEGIDLDLYKHTVFLRVLEKVINCKDEIAQGYLMDCIKVFPDEYHSGISCMEIASPESLVQHQVVTDLRSSELSSTQMQLVDTGQECFSPGFLLSVKSWPAEIKARYVDMDTLETCLLKVTVTANLGMLLTPVARYIYSFRLAGILLILSYFHSRKSEGLDTNLTVITFQIFMARFISGLLIGIDDFFCAVGAAKIHVSRSAFLVSTRLIFSVGIGEQIGDKILFCFRLSALKWHPDKHQSPSQFSKEIGRPCTLLRNSGSQSHSCIDRNGSSGMCRDVGARLNFVNGTQFLSSVESIVDLKSRLKSSADVQHLSSFATVIVIKISIVPINSSIQDMVSQT