lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Transcription factor which regulates nonfermentable carbon utilization (By similarity). Binds specifically to 5'-CGGN(8)CGG-3' and 5'-CGGN(9)CGG-3' sequences in the promoter region.
Subcellular Localization:
Nucleus.
Sequence:
MTKKLPSELKQTRKSIQTACEFCHTKHIQCDVGRPCQNCLKRNIGKFCRDKKRKSRKRIEKHGTQPYLNLGKRLVIHDVPSKTVSPSSVHLQRDFLSSDQEKPGKTPAHNTNIQYTYNINDNFQSAGSIPRITNFNTNNRQTVLENTSNNISASQAVHLMNDPIIPTVRKSTLNLKSHFLEQHKAMQQPLATNCLVATSNVPVHSGMDDSNKSDDDVDDETNIHFDSMWCNDEYMKLKDIVDISTPFLPNNSQIFSLQESEYPNPSASTRGNSSLHLTNLLNSTKSVNDQKDSSIGHSTSTFNTYDEVVSRPFISLDMLHLNRGANANTHPSHNAKLESECDSSSHSDADLEKHDTDFISPSKFRELVKTPQDLYDNKCLIKPHNYKLAYTKLLTTLRKKFLEGAEIDKSASVKDEHSTQKHNLRYDLEVIIRSILERYAPIFISLTSNMIEEDLLLQEVTLQRALLDLENMAKLVSCTPMCIWRRSGEICFVSNEFYSLTGFNKNLLLDRTSFIFEYLDHKSVSNYFQIFNELLAFGYNDINKRKKLLMLNACSSTSSKITEGFSFTTDGKAIFTKCNLLLSNGLYLKCACCWTVKRDSFNIPILVMGQFLPIFEMD
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser), including tRNA(Ser)(UGA) and tRNA(Ser)(GCU). Interaction with SARS1/SerRS is required for N(3)-methylcytidine methylation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MASLQRKGLQARILTSEEEEKLKRDQTLVSDFKQQKLEQEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVVNEYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS
The following text describes a protein:
Function:
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
Subcellular Localization:
Cytoplasm.
Sequence:
MKDNIALIGFMGSGKTTVGKLLAKTMDMKFVDIDKVIEAHEKKSINDIFHEKGQIYFRDLEREIILQESLKNDCVIATGGGSILDNENIKRLKETSFIVFLNATIECLYLRLKDNTTRPILNDVEDKRKLIEELLEKRKFLYQISADYIIDINEHTNIYETVDKIKEIYIIS
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKNISATLAIVWRIAVPYFRSEDKWVGRGLLAAVIAMELALVAIDVLVNQWQNRFYSALQASDWDAFVTQIWIFVALASMFIALAVYKLYLNQWLQIRWRQWLTRHYLGEWLQGATHYRMQLKGDAADNPDQRITEDVKNFVEQTLTIGLGLLSSIVTLFSFVIILWGLSNAAPLHLFGTDLMIPGYLCWGALVYAIFGTALTHWIGAPLVNLNFEQQRYEADFRFHLVRVRENSEQIALLKGEGAERGRLLGRFGLVIGNWYAIMSRTKRLTAFTASYQQAAVIFPYVLVAPAFFAKKIQLGDMMQTASAFSSVQGALSFFVTAYRSLAEWRSIVARLDGFEMSVDSAANLPAHEPAIALEAAGGDRNIGLEQLCVNLPNGTPLVAAGAFAIQVPERVLVTGPSGSGKSTLFRAIAGIWPFGTGTIVVPERAKLMMLPQRPYFPVGVLRDAVVYPAAPDTFDAARVRDALIAVGLPDLAERLDEDGHWNRMLSLGEQQRLGLARALLHAPDYLFLDEATASLDEPSEARLYRLLTERLPQAAIVSIGHRSTLDAFHTRKVTMVKDGQIHVLGKSGEPVQAESTVAR
The following text describes a protein:
Function:
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. May be involved in transport from the vacuolar compartment to the cytoplasm.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MAKFALGHHSEVTEAGCVRAVLAEAVLTFLFVFSGVGSVMAAGRLAGGADTIMGLTAVALAHAMAVAVMVSAGLHVSGGHINPAVTLSLAAGGHITLFRSALYVLAQLLGSSLACLLLAFLTGGAVTMPVHALAAGVGAPQGVLWEAVLTFSLLFTVYATVVDPRRSVGNLGPLLVGLVVGANVLAGGPFSGASMNPARSFGPALASANWASQWVYWVGPMVGGLLAGLVYEGLFMVRPGHQQLPTDGTDF
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEVNGGPANSTVTSEVSLSFQEELTATLQNALGVAVEIAVVEITRLLDRALREVQGQIQEALRDNSALKFRLQTAETQLSSVCGGLDLQTQSLEDFPVSNSSSSGGGQLMPPPLSRAQRGGLQVSAVNIRQQTQSSVNSEQDYLLCEPKDTTVFQRVPMCGNPLAESALNSDSLGEATHYHHGANDTKNEQHGMTKADLSCAGEVSHVLSDPSSLEVAIKVEKEESYGDPIPVSISVAEEPNSDSLSLAQSRLLEDWRPEQLQSESCHTNMPCQSANHPVDFLSLSGSGQQIHFPKLNNRKRPDHFMFPGGRGPYHCIICGRDFNRKHHLKIHQRIHTGERPYTCSICSARFRHALTLKRHFRLHTGEKPYTCGQCGKKFRNDGGLRSHQCS
The following text describes a protein:
Function:
Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
Sequence:
MNIKDYIKENVLIFDGAMGTMLQKLGLKISDLPEELNILEPEKIINIHRKYIEAGAKVITTNTFGANEIKLKQSKFSLESIIDKAIDNVKKAGKNKEILIALDIGPIGQLLEPMGTLKFEEAYEIFKRQIVQGQKSGADIILIETMTDLYEAKAAILAAKENTNLPVFCTMTFEKNKRTFTGCTPLSMVLTLEGLGVDALGVNCSLGPNELGDIVDEIIKYSSIPIMVQPNAGLPTIKAGRTIYNIEPKEFADFQRSIVEKGVRIVGGCCGTTDEFIREIVYSLKDIKIKKLKENNIYGVCSSTKSVLIEGVKIIGERINPTGKKLFKEALRNNDTDYILKEAISQVECGADILDVNVGLPEIDEEETMKKVIKEIQSIIDTPLQIDSNNPKVIEKALRVYNGKAIVNSVNGEEKILDSVLPLIKKYGASVVGLTLDDKGIPKKAEERLKIAEKIVNKALDYGIKRKDIFIDCLVLTASAQQEDVRETLKAVTLVKEKLNVKTILGVSNISFGLPNRELINKTFLAMSLQSGLDLPILNPNNKEMINIINAYKVLNNEDKRAANYIERYTNEISNSREVKIPKNDLTLKEIVMKGIKEESYSKTKDLLKDRGELSIINEELIPALDEVGDKYEKGIIFLPQLIQSAETVKKAFTAIKEKLREDNSPKINKGKILMATVKGDIHDIGKNIVKVILENYGFDIIDLGKDVEAEKIVEEVKKNNIKLVGLSALMTTTVNSMRDTIKILKESGMDCKVFVGGAVLNEEYAKMINADYYAKDAKEAVDIAKGFFGGF
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MLQTVWFQGLGRNLLFQEPVTFEDVAVYFTQNEWASLHPMQRALHREVMLENYANVTSLYPTAGGFPLDTERTEKVPGALSSFLPSSSSLELILALLPMSAFPFPKPDLIFQLEQGEAAWGPDPWTLAGGETLRGMCTGGKTKTENEEKTAQLNISKESESHRLIVEGLLMDVPQHPDFKDRLEKSQLHDTGNKTKIGDCTDLTVQDHESSTIEREEIARKLEESSVSTHLITKQGFAKEQVFYKCGECGSYYNPHSDFHQHQRIHTNEKPYTCKECGKTFRYNSKLSRHQKIHTGEKPYSCEECGQAFSQNSHLLQHQKLHGGQRPYECTDCGKTFSYNSKLIRHQRIHTGEKPFKCKECGKAFRCSYDCIIHERIHTGEKPYECKECGKSLSSNSVLIQHQRIHTGEKPYECKECGKAFHRSSVFIQHQRFHTGEQLYKCNECWKTFSCSSRFIVHQRIHTGEKPYECQECGKTFSQKITLVQHQRVHNGEKPYECKECGKAFRWNASFIQHQKWHTRKKLINGTGLSTVKPYCPCAILSPLPPQHTCSAPAPPGPPLSSSHAVVLPPSVPFFLLLPSSEKANPSPVQIAHFFQDLAFPGKSSLQSPNPLSHSL
The following text describes a protein:
Function:
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
Sequence:
MSFDGKLKAQSILETYKNFDWSKCKLVIIQANDDDSSDSFIKQKLIACNTVGAKSELIKLSNQITQAELIEKIISLNHDVNVTGIILQLPVYPHLDKNSLLEAINPLKDVDGLTTNHLAEIKPCIVEAIITLKELFNLEFNNQKIVVVGLGITGGKPIYEFLKTSGYKVQACDKDTPNTFELIKSADIVFTAIGKSHFFQAKNFKKGVILFDIGVSRNKQNKLCGDINPEGIEKKARWWTKTPGGVGPFTVLAIIKNLWILHEKNKRCLQSSI
The following text describes a protein:
Function:
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MRNLKNVRLAEVHLQNELPLTATAWDTASDAVICTFGPTEANPIIELRRKHQDSYFTDPVGAEVFECIASWDAPCPLPDLRCDRVLSLHYFADNLTACLVLEGGDIVVVREDPLPGEEKIEIVGSVDVGISAAAWSPDEELLALTTRANTFLYMTREFENVAEITFTPEDLKVSQHVSVGWGKRETQFQGKRAKALRDPTIPEKVDEGRLSSNDDGRTTISWRGDGAYVAVNSIEAGFRRVIRVYSREGALDSVSEPVDGLEGALSWRPYGNLIAGIQRLEDKVEVVFFERNGLRHGEFSLRLNEEERASWASDIHLSWNVDSTVLAVLFRDRIQFWTMGNYHYYLKEEVPVVVDPDYPHPFAFKWHQEKALRSVACGSASILDLDFVFDVSHGSTFAPHDVGAVAVIDGMDSNVVDVAFSKSGTRIAVLMKDCFSIYMWSLKTRPVPSPILESSHPLPDNLDNRPRQIAFLNENEVYILRNSGPNSTCIQKTTLETRSTTTVYQTTDSGQILTIFPAVGHEALWFSHVPQPGRPIAYCILKASPEEDVQVDSWDQSPAVDTHWARAVHLSDDERILISLSRTGALYANNQLLAKNCTSFLVTQAHILFTTSQHLLKFVHLTKAEEMEVPADTPETDERCRSIERGSKLVSVMPSKFAVTLQAPRGNIETIYPRALVLAGIRNYIDRKDYRSAFLACRSQMVDMNILHDYAPEQFLENVALFLDQVKRVDFIDEFLSRLSEDDVSQTLYKDTLKTPREVQTTTQPEGTASFKPTTKTSKVNRICDAFLATLEKRMDTNLHNLVTAHDPREYLPFLRKLQQLPEDRRRFEIDNYLGRWAKALKHLHALNAYDEIRVYVIKHELYKEAIDLFKYQPEQLRDITHIYADFLHDHSKYKEAGIAYESLSLYEDAYKCYHLAHLWRESLYCALMVPLSEADLTAHALALTTTLTEESRDYVSAAQIHAEHLHDIPAAARLLCRGSRFADATRILTLHGKKDLIPEIVDTGLADAMGATTDLLADFRSQLNAQVPRIRELRERRAADPLAYFGGDPTTDDLGVDIPDNVSLAPTDASTLAGRTMFTRYTGKTASSRHTSKTRRREERKRARGKKGTVYEEEYLVNSVRRLIERVNSTVPEVETLVDALLRRGMRERAVAIEKAMQEVLKMCAQSREEVFGALEQNESEKNAAEGLDKEDVDGAEELRPRGGQRVFAESVRSVLGTSIPGREVPPVKEMKKSALLN
The following text describes a protein:
Function:
Phosvitin is believed to be of importance in sequestering calcium, iron and other cations for the developing embryo.
Sequence:
LTLTIVGSQQITFEPTFSGSKSYQYKYEGILLSGLPEKGLARAGVKISCRVDISEVAQKTYLLQLLQPVIQEYNGIWPKAPFHPASKLTQALQRQLTQPIKFEYRNGHVGHIFAPAEVSDTVVNLHRGILNMLQMTLKATQNVYELQESDISGTCQTSYVIQQDRDSDQIIVTKSKDLDNCEEKVQKNMGMAYIHQCPTCTKFGRNLRGTAASTYVLKPMRASPSGFLVTQVTSQAVYQFTPFSEINGAALTEASQKLILEETRGARANFLEQQFQNRGRLQYQFASEILQSPIQLFRTQSPEIKIKEVIQYLIQNNEENVPMNAPSKFLELIQLLRACSKGNIEAIWRQYENTKQYRGRRWFLDALPAVGSPTVFKFIAERILKRDVSTTEAGQMLVTAMHLVRASHETMEMAMELLNSLENLKWQPVYKLAVLAYGSMVNKYCGRPEDCPATVLKPLHDMAADSMSRAHEEDIVLALKAIGNAGQPASIKTIMKFLPAFSSIANHLPVKVQADAVMAMRNIARKQPSKVQEITLEIFMDRRLQPEVRMIASIVLLEAKPPLALVVTVAEALLKETSLQVASFVYSHIKGLSRSSAPEHHALSAACNVAVKLLSSKLDRLNYRYSKAIRMDMYHYNLKAGAAMNMFLMNSAASVFPTAFITKLQASVLGSSSDPLELGIRAEGLEEALEKYEDEFTNMPTSKKIEKVLKMLSRWKSVPSEKTLASAYIKLFGQEISFSRMNKKYIEEIMQAIREPVERQTLIWRIVTQLQSGTAVQQSIPLLVAEMRHIIPSCVGLPIEMSLYSAGVATASINAQMQITPTLAREFSVTQLLNSELQLKTDATTSFTMNAVAVMGVNTHLIQTGVELQARVHTVIPMKFTAKLDMKEKNFKMQFEPCQTETELLMMRAQAFAVTRNVEDLEAAKKTPLLPESAQAEIMKQHFDPEASAPRRRDSAEAMTRLSDEMISPGSVTSDEQRRKHSSHRMYNVCTKIRNFGFQLCFEAKSENAAFLRNTPLYVMIGQHFYKIDLRPAHSSDATVEKIEVEIQTGPKSASKIVRMVAIDEYPRAKKLAGSVLTKLKGILKPFKGHHHNATGISWRSGHHHNATGISWRSSSSASSSHYHPQSRRTSQKNRHRKKDHNRHPRVGGHFRRHGTNTSMSSSSSSGSSSEMVRGEAYVSMIKSLNFRVFISLKEIDYSQTWRNCRKTTVSLRSIRSKTMYRGRADNFNLRFKAHGHLLQGDPGNARPFTSSSSSSSSSSSESSLASKPEFKFLGDSTSPLFAVVARARRSDGLQQGYQLAVYADTTLSKPRVQALAIEINSKDKWQVCADAELHNDYKALALVRWGQECREYKVAVKAATGRIATHPALQVKAKWWKIPRAMKYAGETMAEYVPGAALMLGFSQKWHKHTSKQLALYIAMSSPRTVDLFIKTPRMALCKQAVPVPVAMPYGPIDEMQKPLGLLHSLSEVPIMLAESTKSQCSVHGSKVVTFNDVRFSYDMPRSCYHILAQDCRSRPKFIVQIKRATVSQSLYVVRAQIHNNDIEMLPSTSGALRLIFNDNKIPSSNLPFSDPEGMIHIDKEGQGLVLKAEKYGLEKLYFDGRKTQVKVGYTMKGKTCGMCGHNDGETKKEFRMPDGRVTKSAS
The following text describes a protein:
Function:
Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MEVKARAPGKIILAGEHAVVHGSTAVAAAIDLYTYVTLRFPLPSAENNDRLTLQLKDISLEFSWSLARIKEAIPYDSSTLCRSTPASCSEETLKSIAVLVEEQNLPKEKMWLSSGISTFLWLYTRIIGFNPATVVINSELPYGSGLGSSAALCVALTAALLASSISEKTRGNGWSSLDETNLELLNKWAFEGEKIIHGKPSGIDNTVSAYGNMIKFCSGEITRLQSNMPLRMLITNTRVGRNTKALVSGVSQRAVRHPDAMKSVFNAVDSISKELAAIIQSKDETSVTEKEERIKELMEMNQGLLLSMGVSHSSIEAVILTTVKHKLVSKLTGAGGGGCVLTLLPTGTVVDKVVEELESSGFQCFTALIGGNGAQICY
The following text describes a protein:
Function:
Involved in a TGF-beta pathway. May be a receptor for TGF-beta-like ligand daf-7. Controls the decision of whether or not larvae enter a developmentally arrested state, known as dauer, in response to environmental conditions. Regulates body size and male tail patterning. Involved in regulating entry into quiescence triggered by satiety. Involved in sensitivity to CO2 levels.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MNQKGTVRLKALVLICLPLFLIATPVPVAVTEDDRQDRIESEAAEKEWANTLVSKVAQSNGTGTIKVSAPAKPTLRRMDNEEDEVISIECVYYDEMECEKSGDCEITKKTCYSEAHLKAVGCLAVFGLPTQEINSTEPYLKVDKPQYKSLGCMPYQHADSMNCENESSCRQGRSFRGGIGMCCCSTNNCNMPDLIEMVNPSLKKDSDNSALLWASTPSNMDLESLDKFPFYWIIIIALSVILCIALLILAYVGWKFQQNKKEEIKKQQKIKFDMEKTDALEAGNVPLVEPEEEMIEMVETPKELPITDFQLISKGRFGKVFKAQYTPDSGEKRLVAVKKLNEFQKASFLAEKRIFDELNEYPKWYKSIVEFVCAEKIGDEYWIVTEFHERLSLYELLKNNVISITSANRIIMSMIDGLQFLHDDRPYFFGHPKKPIIHRDIKSKNILVKSDMTTCIADFGLARIYSYDIEQSDLLGQVGTKRYMSPEMLEGATEFTPTAFKAMDVYSMGLVMWEVISRTKLHQTDEPPNYQMPFQVIGFDPTIGLMRNYVVSKKERPQWRDEIIKHEYMSLLKKVTEEMWDPEACARITAGCAFARVWNHIMSSPDSSEGYHSGSSMKNRGVDDVEQSEKPEGIEEMQHYHASSPSKRQHPSPNPFFDSCPPPPPIPVILENGGILQPDNAEPEPEELPDLPIVEKIYDIATNMLFSREELDLMNAQRQVEYEAGADTRASTPTPSGTFGTFTT
The following text describes a protein:
Function:
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.
Subcellular Localization:
Cytoplasm.
Sequence:
MIDYHEKETIERQIETILPCQSLQTTEQLLDTFEVQSTADLIVSLYKNKVCSDPTALSVVVAFQFPDSLLSYSSAVVEHLYEHIGKNIQCKVDLVVLADTTFGSCCVDTVAAEHACVDLIVHYGPSCLSRPASTFPVLVVLEKAPIDIPATVAYFISQFSLDLLQPVLVMYDLAYHHAAQHLAQALAAAGFIHLIWPHIETVYNMPKLDTNDIQHKPEMQGQKYILPEGVQIQDVTMFYIGGESLNLTNLMMTHSMCKQVIAYNPVLNTGSVQSGSANKLLMRRYFMVQKAKDADVIGIVVGTLGLASYLPVIENLKRLVLASGKKPYMLALGKPSPAKLGNFLEIDVFVLVACPQNALLETRDFLRPVVTPYELCIALDRNAEWDVSKYQLDLVTVDHQLSDTIHRIAERQMTRTNLDNGDGLDDSDDDQPHFSLVTGAYKQRKQYVSIVCSTDDEPTQGDSSALMARSRDNVISKYTSTSAAAEYLNNRTFQGLEAMVGQTTISDVQDGRRGIARGYINPNVEAKNDDSLDKS
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MEAYSRDFLRAIGEGDDESRRGEEMTGMKMEVDLTLELSLGGRFGLQRRSSERLAGSSSSSAASALAPPVLVDYLSAVRGTRSLSRQGTSWSLADLETELMEEMPGVCTVGLPRTAEGLLYRYKEEEGDVVIACLCHGLFLSPEEFLKHAGAVNVENATHRIMTK
The following text describes a protein:
Function:
Acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Acts by binding to angiotensin receptors AGTR1 and AGTR2. Also binds the DEAR/FBXW7-AS1 receptor; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis; Is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets; Stimulates aldosterone release.
Subcellular Localization:
Secreted.
Sequence:
MKMFLAFLFLSCFAMARTNRVYVHPFNLFSSENISCEVIQSEEHKPLETVHPLPPLPGSTDPDPRTASAAESLKNLTQRTAVLAELQNSLGLRMYQTLSRTQKHTNTLLSPLNAFGALVTLYLGASKKTAISYQQLLGLNLESEQTDCAYFVDGHTVLRTLQAISAHVDESRKELRTLVWTFVNSDADLSKEFLRGTQDFSDDSFVRSVDFSQAKDAEVEVNNFIQKTSDNKVKSMFKGVTPKTDLLFASSVHFKGNWKTAFQPEATSDQDFWTQKNSSVQVPFMMHTGDYKYLDDAGRKCSIVRLGLSKRTFMLLVLPHEGASLQDIEKPLLTVIPTWLRHLKEKYLELSLPKFSLTAVTDLRSVLSEMAVEKYLMGSDASFRRMSSKENFTVDKVLNKVVFEMTEGGSEVQNRTDDGRAPHKVTFNRPFFFAVVEGNSNAILMLGKIINPTA
The following text describes a protein:
Function:
Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation. Catalyzes the transfer of CoA moiety from succinyl-CoA to L-malate to yield L-malyl-CoA (By similarity).
Sequence:
MDGTTTTLPLAGIRVIDAATVIAAPFCATLLGEFGADVLKVEHPIGGDALRRFGTPTARGDTLTWLSESRNKRSVTLNLQHPEGARVFKELIAHSDVLCENFRPGTLEKWGLGWDVLSKINPRLIMLRVTGYGQTGPYRDRPGFARIAHAVGGIAYLAGMPKGTPVTPGSTTLADYMTGLYGCIGVLLALRHREQTGRGQYIDAALYESVFRCSDELVPAYGMYRKVRERHGSHYNEFACPHGHFQTKDGKWVAISCATDKLFARLANAMGRPELASSSVYGDQKVRLAHASDVNEIVRDWCSSLTRAEVLERCYATATPAAPLNDIADFFGDRHVHARRNLVAIDAEDLGETLIMPNVVPKLSETPGSIRSLGPKLGEHTEEVLKEILGMCDEQINDLRSKRVI
The following text describes a protein:
Function:
Needed for flagellar regrowth and assembly.
Sequence:
MAAPAKFLFDTDFAAPDRTREKAATAAEIAQKVAEAEARAYQDGFAAGQREAKAESDRRVALAMEEINIAIRGVASGMGNIEIKMETEAVEVAVAVARKLCADLVAAEPLGEIVALVKDCFSHLVATPHLVVRINDALYDSAREKIERLAKQSGFEGRLVILAEPEIATGDCRIEWADGGVVLERGAIAAKIDEMVGRYIASRRGS
The following text describes a protein:
Function:
Potassium transporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAQQAAGTVAVCTAAAAAEGRNKAAAANKQQQASSCCSEHDEDMADLELALELPMGVQRQDSLYRDATRAGGGGGNGNQQQEGWARTLRLAFQCVGVLYGDIGTSPLYVYSSTFTGGIRDVDDLLGVLSLIIYSFLLFTIIKYVYIALRANDDGDGGTLALYSLISRHAKVSLVPNHQPEDELHTTDDAAVLGKRGSMRRRSVQLASHREQRAVWVKELLETSKPVRISLFFLTIVATAMVISDACLTPAISVLSAVGGLKEKAPNLTTDQIVWITVGILVVLFGVQRFGTDKVGYLFAPVVLLWLVLIGGVGVYNLVKHDMSVLRAFNPKYILDYFRRNGRDAWVSLGGVLLCFTGTEALFADLGYFSVRSIQLSFGFGLVPAVLLAYMGQAAFLRRYPEQVANTFYQSTPESMFWPTFVLALAASVIGSQAMISCAFATISHSQALGCFPRVKVLHTSRQYQGQLYIPEVNLLLAVVACVVTLAFKTTTVIAEAHGICVVLVMLITTLLLTLVMLLVWRVNAACVALFFAVFAAAESVYLSSVLYRFAHGGYIPVAMSALLVAVMVLWHYVHVKRYEYELERTVSHESVVRDLLPRCRTVPGVGLFYTDLVQGIPPLFPHLVDKIPSIHAVLLFVSVKHLPVPHVDATERFLFRQVTNSTGNGNGNVAATGSTLTPGSSPRVFRCVARYGYRDPLEEARDFAASLVERLQYYVRDVNLYGVDHQQPGAKVSYPSSRCDSMVLRRQRSVMMLRQSSAASYYSYTTETAATTQQQQLARARSTSGGMAMGILHHSSSASCAERAEQLARARSTGIFAEEMLTPAESFSELSRMGSIGGMQQHQAAAAAVKISLEEMARIEEEQRFIEREMDKGVVYILGESEVVARPHSSLLKKLLVNYAYAFLRNNCRQGEKMLAIPKSQLLKVGMSYEI
The following text describes a protein:
Function:
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVASIREDLSVYLLRHRNCHCHRHFSACLVGAAIKAPRMNSKNLISTRLLYMVWASFFETKLDSRWLCSVCFWIIVGFINLVCGLCIGIIGRNCALFDAQNSSFIVKIVVIESFGSLLGLFGVIVGIIILVSDAIKAPRINTKNLIKSLTGGYAIFASRIIVGFVNLVCGLCIGIIGSNCVLSDAQNSSFIFRIL
The following text describes a protein:
Function:
Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement inactivation and phagocytosis resistance.
Subcellular Localization:
Cell surface. Cell outer membrane. Note=The C-terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface.
Domain:
The signal peptide, cleaved at the inner membrane, guides the autotransporter protein to the periplasmic space (By similarity). Then, trimerization and insertion of the C-terminal translocator domain in the outer membrane forms a hydrophilic pore for the translocation of the passenger domain to the bacterial cell surface. Presents a lollipop-shaped form which consists of three domains: a C-terminal membrane-anchor domain, a coiled-coil stalk domain and an oval N-terminal head domain. The N-terminal half of the sequence reveals the presence of repeated motifs with the consensus sequence NSVAIGXXS. They form the turns and hydrophobic core of the nine-coiled left-handed parallel beta-roll and trimer structure essential for the collagen-binding activity.
Sequence:
MTKDFKISVSAALISALFSSPYAFADDYDGIPNLTAVQISPNADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDRENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENTNKRSAELLANANAYADNKSSSVLGIANNYTDSKSAETLENARKEAFAQSKDVLNMAKAHSNSVARTTLETAEEHANSVARTTLETAEEHANKKSAEALASANVYADSKSSHTLKTANSYTDVTVSNSTKKAIRESNQYTDHKFRQLDNRLDKLDTRVDKGLASSAALNSLFQPYGVGKVNFTAGVGGYRSSQALAIGSGYRVNENVALKAGVAYAGSSDVMYNASFNIEW
The following text describes a protein:
Function:
D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
Sequence:
MELLVAYVDDPAGHNMAKFLCKDMTQDGDVFRGKYYDLIIIPTPAISADWLEEKYDYDGFVFLSKHAAESGVLALTCHSTGNFSEAKFGGKDRQVAIPHPDLQKKYLQTLRDHQSDFVEFDITIEATHHGPTDLKKPSIFIEIGTTEKQWTDENLCHRVAKFVHEVMSNDIPKNPVAICFGGTHYPTKFTEQLLDGKYALGTVIPKHALDNLDEELFSHILKQNNMAKFALLDWNGLGPNKQKVLDLLESTELEVIKL
The following text describes a protein:
Function:
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.
Subcellular Localization:
Secreted.
Sequence:
MAVLPLSGAIRLSRGDLVIETQTQDPWAKKLITQGTDKACADLDVQQIQALKMKCAMIMFAQYVQGNTFGQVVKMAEAVTDLAKKCTEVDRDNPNCRKPLDWIFLNTICQEDNLPRFTDCCAKKDPERNDCFLSLKNSSRGFISPFERPNAEAACKNYSEHRHSLPGYFIYEVSRRHPFLYAPTILSVAIHYDEMMKDCCRSAEDSTHNLEECFRRQAPKVVKPIREDGLRQEHTCGILKKFGERTIKALKLVQISQRFPKADFFTVTKLVSDIANMHKDCCRGDMLECMRDREEILHYVCTNQDVISSKIKKCCEKPLLQRSECIVNAENDDKPANLSPQVREFIEDKGICERFAQEKDTHLARFLYEYSRRHPEFSAQMLLRIGKGYEDLLDECCKTGSPDNCCSRGEEELKKHIYETESVMKTSCDIYKEKGDYYFQNEYIKFTKQMTTIGSKCCQLSQDKLLPCAEENVSLLVDLVLGEICRRHLTNPINPAVCHCCSSSYALRRPCMGKLEIDENYVPLSLTPDLFTFHEDLCTTEEEKLQHRKQEFGIPLLLSYPMLINLIKYKPQITQEQLTSITVAFTAMREQCCKEENREACFAKEVLVTLSPICS
The following text describes a protein:
Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
MEEKFHSNSTIVNGTAANQKLIEGHNLWEVITIATVTAILSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTSYILIGHWFPWKLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPRRAGIMIGLAWLISFILWAPVILCWQYFVGERTVPPGECQIQFLYEPIVTFGTAIAAFYIPVSVMTILYCRIYKETEKRTKDLAELQGSSSVVEFETIKPQKTLLKSCFSCKQQKLVKRERCQASWSSSSRSISATAKSQIQNTCHDWSKVDQLTTCSSYASSEEEEKHGSDPVFQVACNTPVKGNDDEHKEEKREAFIKDHQRENEYETQKYFLTPTKGNVEKSNKCIAYKFRLVVKADGAPEANNGCRKVKITPCSATLSKDTSVKNTDPNINSQMTKRKRMVLIKERKAAQTLSAILLAFILTWTPYNIMVLVSTFCSDCIPPTLWHLGYWLCYVNSTVNPICYALCNKTFRKTFKLLLFCQWKKKKMEEKLYWQGNTKLP
The following text describes a protein:
Function:
Has E3 ubiquitin-protein ligase activity. Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation. Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation. Inhibits PPP1CA phosphatase activity.
Subcellular Localization:
Nucleus.
Sequence:
MDDLTLLDLLECPVCFEKLDVTAKVLPCQHTFCKPCLQRIFKAHKELRCPECRTLVFCSIEALPANLLLVRLLDGVRSGQSAGRAGSFRRPGVLTSQDSRKSRTSPRGLQSSPFRLVPNIRIHMDGVPRAKALCDYRGQNPGDLRFNKGDVILLRRQLDENWYQGEVNGVSGVFPASSVEVIKQLPQPPPLCRALYNFDLRDKDKSESQDCLTFLKDDIITVISRVDENWAEGKLGDKVGIFPILFVEPNLTARHLLEKNKGRQSSRTKNLSLVASPSRGKAVNTPTLRRGPGSRRKGPGQFSITTALNTLNRMVHSPSGRQMVEISTPVLISSSNPSVITQHMEKADVPPSSVGQVSTYHPAPASPGHSTAIVSLPGSQQHLSANMFVALHSYSAHGPDELDLQKGEGIRVLGKYQDGWLRGVSLVTGRVGIFPNNYVIPIFRKTSSFPDSRSPGLYTTWTLSTSSVSSQGSISEGDPRQGRPFKSVFVPTAIVNPVRSTAGPGASGQGSLRKGRGSMRKSKWWQRDGSLQRPVQPGNPTLVVGSLRRSPTMVVRPQQFQFYQPQGVPSSPSAVVAEMGPKPTPTGEPALTCVSRGSDTRIHSAASSLIMEGKEMPIKSEPLPKPPASAPPSILVKPENSRNGTEKQVKTVRFQNHSPPPTKHYTSHSASGKPEQPATPKGPQPEAAPLGPEMTILFAHRSGCHSGQQTDLRRKSAFGKTMTPVSTASATQTVFPSK
The following text describes a protein:
Function:
Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKLMPRVHDWYVGRAVLFTVLLTWAVLLGLDVVNAFASEAKSIGQGSYSFGHAIAFVAYTVPRRAYTLFPTAAVIGALMGLGQLAATSELTALRALGVSRKRMSASVVVAMALLTATMVISGETVGPWAQSQADTLKTSARYQSDMTSARYSGLWAREGDTFLNALSGEEQLLDNGGTALTLHDVRLYHLDANGQMQQLTYAAVAEHREGRWTLRQVRRDTFQARSVQRETFPELPWQSQLNPKALAAGLAKPRNLSVHDLGQSIEYRRRNGLDASDYEDQYWSRWFYPLNVLALCLAAIPFSFGSLRSGGLGKRLFLGILFALGFWLLQLFFGRMAGALKLDYRIAYALPPMVMLGVSAWLFRRRSS