lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
This promotes the activity of RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MSEPCQHPELYGQLCTRCGEEVSVDELQNHQPIVGGGISNVGLSVRRENAQQYGQENANKLLEARKLILILDLDKTLIHSTIDSIASHWLREGVYDIFHFDLGKHTYYTKVRPGLHAFLEDLYPYYEMHIYTMGRRNYAERILRIIDPSNRFFSTRILTQDESFSIENKAKNLDALLPGGDSMAVILDDLPAVWDFQTNVVPALPYEFFKHVEEVNAIPQQRSQSDRRMARKHEALQRMHASNAIRITDRLIEPLYRAFRQHASTMTEENPEHQAHQATTDAESWSNAVALALVTHLRTAIDWDGLEAISSAVDSFCKTLTLNEDQRKEVQQWARDQEEQVREALRASQTHSNATQHGRDLQRRARLAEDVVRNEVLAAAEAVATAFRDLECTFEVVPLPPYAAHYCCCGTETIIIKARKRHVGNAGPVLAERFAAARRFILGQATCLRDLTVNQVEIEADFGSWLCQLVRNEKEKGVDEAIRSRLRCFEPLDAALLVMVAKRFCPCDAWAPDVDTSAILSVILDTLRSAPERRLRLAAPPDRDPTLRVVGTALKTLHTSFFDQYDRGIKPNTRDLLPNIASLTETYPPWALAGCILLFTGIIPKGQDVATHRAWRQAVAMGARVVDEVKFASILMSRRVTHVIARKAGTEKLNQALDYPGVFLVSLRWLEDTFHQGARAKESKYPLEGLPSCVPSRSKPAHKTASQTAPPSNRTASEGPEPEKKRSKWAALADELDDELGDLTSEDEEDEDQSEAKVVYSESEDDRARKQPVPRAALPDDFHTWRKPKRTVQRESEGSESRDSAPQPAQRRQTATLDELEEKGYTMKNDSDADEDAEESFDEVSASEDEGGMDLTGE
The following text describes a protein:
Function:
Telomeric DNA-binding protein that is required to protect the 3'-end telomeric overhang and involved in telomere length regulation. recruits poz1 and ccq1 to telomeres, regulating telomere length negatively and positively respectively.
Subcellular Localization:
Chromosome, telomere. Nucleus.
Sequence:
MSNCLKHPWLENGLLNLIKNADVLPIRVFKCQPLQIFEYIRYEHPIRCKLSDTEFYIEAEFSSQSISDLNNFTEKRITSLRGGIVTLGNFLIHLIPSQSGIIPWIQVESFNFQGCEGAVFGNPKAITTSALFNALLQSPYLAALANEFNRSIKEGSSYQEASLSQQEKPNDNTSNSRDIKNNIQFHWKNMTSLSIEECIIPKGQQLILEKESEENTTHGIYLEERKMAQGLHNSVSETPEVKQEDNDEDLDAYSWSSSTDSAGEIPSLPTNRKILEKIAEKPPPFESPLEDDETPDQTNEHEANQVNVSQLPLNPRGSGISGRPVESTEQLNSSLTIERSQSIQSTDSKQRVETQSHRRSKIEIFDAQDELFDRSICTTIDDSTGKLLNAEETPIKTGDLHSTSASSVISCTPPAINFTSDICNEQIELEYKRKPIPDYDFMKGLETTLQELYVEHQSKKRRLELFQLTNNHQKNSEACEMCRLGLPHGSFFELLRDWKKIEEFRNKS
The following text describes a protein:
Function:
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
Subcellular Localization:
Cytoplasm.
Sequence:
MNTSNITFIGGGNMARNIVVGLIANGYDPNRICVTNRSLDKLDFFKEKCGVHTTQDNRQGALNADVVVLAVKPHQIKMVCEELKDILSETKILVISLAVGVTTPLIEKWLGKASRIVRAMPNTPSSVRAGATGLFANETVDKDQKNLAESIMRAVGLVIWVSSEDQIEKIAALSGSGPAYIFLIMEALQEAAEQLGLTKETAELLTEQTVLGAARMALETEQSVVQLRQFVTSPGGTTEQAIKVLESGNLRELFIKALTAAVNRAKELSKTVDQ
The following text describes a protein:
Function:
Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MDQKNNNLFQKAIEEVFAVSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMFQMGLKPTTPYKKSARAVGEIMGKYHPHGDSSIYDAIIRMSQSWKNNWTTVSIHGNNGSVDGDNAAAMRYTETRLSLYGFELLKDIDKKLVSFINNFDDSEKEPTVLPTLLPNLFINGASGIAAGYATNIAPHNTNELLDSLCLRIDQPNCELKQILKIVKGPDFPTGGNVYFEKSLSDIYQAGKGKFIIQAKYEVNKNLNQIEITQIPYETLKANIVKQIEEIIFDNKLSAIESVIDSSDRNGIRIIIKHKDFLPAEKIMAFLFKHTQLQVNFNLNNTVIANRFPIQIGLLSYLDHFLKFCHELIINKAKYELELASKRLEIILGLIKAISIIDKIIKLIRSAVDKSDAREKLIDNFKFTFNQAEAIVSLRLYQLTNTDIFELNQEQNELEKTVISSEQLIASEKARNKLLKKQFEGYKKQFHQQRRSQICGFINQKKVEESELIENKTYGVLITKAGNYHKFESNQLLKSTTDFKSESDTIIFAQTIANTDQIFIVTSLGNIINIPVYKLAFNSKNKLASLVSKKPILLEYETIVFVGTMNSVNQPILVLTSKLGMVKRIDLTKLNIKPLKATLCISLRDKDHLVSAFLQQDDKLICLVSDHNYYTVFHTNEIPLISSKGMGVKGMKLKLEDQIKFVVAFEANEPLVMICSDGSVINLKQTELVVVSRMATAKKLPVKKAINYCFSDATNTQLINFQGKNGSKLITTSELNQMSKTAISQTRFNKLN
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
Sequence:
MPVEEAFVQGSGMEVLTNAEMQRADQLSIAAGTPGFKLMLSAGQAVAEAANALVEEGPILIVAGPGNNGGDGFVAAAELAAQGREVSVILMCERDQLQGDAASAARGWKHPVLPFNPQAIGKPALIIDALFGAGLSRPVDGEARAMIEAVNANGALVLAVDLPSGINGTSAAVLGAAVNATETVTFFRKKPAHLLLPGRMHCGRVRVADIGIDAQVLDEIRPQTFENDPDFWGAAFPVPRIDGHKYARGHVLAVSGDAAATGAARLAARGALRAGAGLVTLASPRDALAINAAALTAVMVRPVDTAIEFGELLGDKRYNTCIIGPGTGVGDRTCDFVHTALGAQRHLVLDADALTSFAANPERLFESIKASHDNAVVLTPHEGEFPRLFSDLSNKHPGRSKLERVRAAAERSGAVVLLKGPDTTIAAPDGRATIAANAPPWLATAGAGDVLSGIIAGLLAQGVPAFEAASIGVWMHGEAASEAGPGLIAEDLTETLPAVHRRIYNALGIEY
The following text describes a protein:
Function:
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Recruits VPS13B to the Golgi membrane. Regulates the compacted morphology of the Golgi. Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells. Plays a role in neuron projection development.
Subcellular Localization:
Cytoplasmic vesicle. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus membrane; Lipid-anchor.
Sequence:
MSVGNDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVAAALPGMESMQETSKEGMIDIKLDKPQEPPTTEGGCSC
The following text describes a protein:
Function:
Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC. Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, but a minor proportion is also found in the nucleus.
Domain:
Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
Sequence:
MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKVSQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGITVPEKLKEFMPPGLQELIPFVKPAPIEQEPSKKQKKQHEGSKKKAAARDVTLENRLQNMEVTDA
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MSNVTLSDFLLIVLSFFVPFIVVGIRRGFCTADFLINICLCALGIPGIIHAIYIVIKYPRTVRLDIENSPNDPLVRYTPNPEHAVSPHSGPAPPSYSSLASNDNKHQSP
The following text describes a protein:
Function:
Together with PCH1, regulates growth and development adaptation to the ambient environment by controlling negatively phytochrome B (phyB) dark reversion, a temperature-dependent thermal relaxation process during which phyB reverts from the active to the inactive state. Contributes to red (R) light-triggered photomorphogenesis. Promotes various light responses such as seed germination, hypocotyl gravitropism and chlorophyll biosynthesis, via direct interaction with PIF1 and COP1. Prevents DNA-binding ability of PIF1 to negatively regulate the expressions of its target genes. Facilitates the physical interaction between phyB and PIF1 and the subsequent light-induced degradation of PIF1.
Subcellular Localization:
Nucleus. Note=Observed in subnuclear light-induced structures called photobodies.
Sequence:
MSEHFMGLSKIKTESCVHGYESAWLSRWTPSNKNAKEIHLPEDGHLLKESTGPMKLKGKMLTLFPNLDSPVQSVDVIPDMNKEPPIVADRENSIDGEEEEASSQATQSKNVEHFLNNNTNLLRECKRIWSDSETNSRSQVKRLKTNAADNRGNETKNMMVFEEGPSGKKVNHFFHSIFGMTNLGSRRYQKFSTSQNKNLNMGEAEDVNPWIQRWCKRKAADVHEPRGGQEVNSNGTVLEKQQFPSIAAMAMMRKALSGINPTGCRKTNSLFVWNAEDLS
The following text describes a protein:
Function:
Lacks antimicrobial activity. Does not inhibit the formation of NO by neuronal nitric oxide.
Subcellular Localization:
Secreted.
Sequence:
ASAAGAVRAGDDETLLNPVLNSLDNLVSGL
The following text describes a protein:
Function:
C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins such as unc-5 and mig-21. Mediates the attachment of alpha-mannose in C-C linkage to the C2 of the indole ring of tryptophan. C-mannosylation takes place in the endoplasmic reticulum and frequently found in thrombospondin (TSP) type-1 repeats and in the WSXWS motif of type I cytokine receptors. Required to orient neuroblasts QL and QR correctly on the anterior/posterior (A/P) axis: QL and QR are born in the same A/P position, but polarize and migrate left/right asymmetrically, QL migrates toward the posterior and QR migrates toward the anterior. Required with unc-40 to express mab-5 correctly in the Q cell descendants.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAKKPKNSPEKSKYSSDTSSSLYSQTWLASVVIIGLLVGYINYQHVYTLFENDKHFSHLADFEREMAYRTEMGLYYSYYKTIINAPSFLEGVQEITHDTVTEHGHEINTLNRFNLYPEVILAFLYRPFRAFAKSANWQIELCWQVNRGELRPVESCEGIGNPHYFYITGVFIVAGTVASSIFYLGVLVSDSIFGGFLSVLCFAFNHGEATRVQWTPPLRESFAFPFIIGHIAILTFVIKYKKSGHSMILLLTSMAVPALLFWQFTQFAFFTQICSIFLAFSLDLIPFSTAKTVIHSHIISFLIGFLLLFGNEMMITALYFPSILALGMIIYISPLLSNLKFRPAYVLFLAIIFASITLGLKIGLSKGLGIEDDAHIFDILRSKFTSFANFHTRLYTCSAEFDFIQYSTIEKLCGTLLIPLALISLVTFVFNFVKNTNLLWRNSEEIGENGEILYNVVQLCCSTVMAFLIMRLKLFMTPHLCIVAALFANSKLLGGDRISKTIRVSALVGVIAILFYRGIPNIRQQLNVKGEYSNPDQEMLFDWIQHNTKQDAVFAGTMPVMANVKLTTLRPIVNHPHYEHVGIRERTLKVYSMFSKKPIAEVHKIMKEMGVNYFVFQLMNCSNDERRPECVYRGMWDEEDPKNSGRTALCDLWILAANSKDNSRIAPFKIVYNANRNYIVLKI
The following text describes a protein:
Function:
Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFPVSVWLRKETRV
The following text describes a protein:
Function:
Rhomboid serine protease that catalyzes intramembrane proteolysis. Mediates quorum-sensing and the subsequent regulation of target genes via activation of the Tat protein export system. Catalyzes the proteolytic activation of TatA by removal of its N-terminal extension.
Miscellaneous:
MISCELLANEOUS: AarA deletion mutations display alterations in cell morphology and total or partial loss of yellow pigmentation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAEQQNPFSIKSKARFSLGAIALTLTLVLLNIAVYFYQIVFASPLDSRESNLILFGANIYQLSLTGDWWRYPISMMLHSNGTHLAFNCLALFVIGIGCERAYGKFKLLAIYIISGIGAALFSAYWQYYEISNSDLWTDSTVYITIGVGASGAIMGIAAASVIYLIKVVINKPNPHPVIQRRQKYQLYNLIAMIALTLINGLQSGVDNAAHIGGAIIGALISIAYILVPHKLRVANLCITVIAASLLTMMIYLYSFSTNKHLLEEREFIYQEVYTELADANQ
The following text describes a protein:
Function:
May play a role in polarity establishment and bud formation. The MSB1 gene may be functionally redundant.
Miscellaneous:
MISCELLANEOUS: Present with 172 molecules/cell in log phase SD medium.
Sequence:
MNDMAKPLPTPPTAEIRKSRSNSPKKAQKTNLSPNKNQNNEKNVPRSNGRTKNEHNSMDDEEFEFFHQFSREKVKGVIHVITAELKEKGPDVEFLMIPFRPEQTNDKLLTLLNQLFPLGNGQPVNEKKQLRIVSKADVWTLFQCLKYIWCRLPNSEIIGWKSYLEFKFREEDKKFPRKSFLEIMPQCLASPNHASIVYDFFDLIISISSNSRVNKMSARKISKMCAIWAFSKQIPNSDIQDYDFESAAMKSFAPNNSIQDGLDQWIPASDAMFHLLLAFLRSFVPQDLESAKLPRTLKSLLFNNQYPPRKSTAYTSETILTIPLVTLKTDVFSRKPWQLLERCNDLLDFSDHDAFEAREDYALLKSLFRKKNTVEGISRKMSQESRRLMKAMSTKHSTFQPGWAPRECIENISHLKECIEVKRLDIDDYFIWTWLSSLSFEQTSEKKKIFGRSIILEFEFDGFKKWVVFQECDITLDYNKKGQLKKKTSAQSPTTEKELPPDDFELEDPPLSKSPTLSQTYKKFQAEVPQQSTVRRDSAPDNQGIYHTVISKNALTKNKHNVNLHSFEHKISKWNPLNNLRKKSGSNSSSSSFEEKSKDAPIREEYHTNKNHKSKKEERVLSQFSTLNPDEYQLPVIETGSSNFKIEIPELMYEHDDDDSDKLKNSQKRATDSAIEELNGMVEEMMINEPDDVKISITEAETFESLTKFDQYKPSNITDDDLQSSHSSAVHSLKLSTNTNDSCADSSKYTADRKLAEPRKISEESKVNDDSSSYYSPNINNLPASRMPSQPTYSNSDSKKAFTNESRLNVLQGAVSPSQQVTPKPYKNAPGDCVSPVQQKYYQNDRRNEMSPASAPVPPSAYSPARSPQFSTNSAGFKQNTINVPVGYNDPAHVLANQPHMTYRDQHNYPSHQQKQRPFQNNIVPPELKSRNQRADASPIPQHMVPVKQGVPNLPSNVPLYQQMERMNPNHQHPVNTYKVTQPPYHNNTTNAYGNSRAGNAHMLDGKWSNNPPQMVPKGVRPNQYPQQHVNRYSPQAQPVVPAEYYNGPPPMRAPPMMSHMVPAQEPIRYTAGANRRSFPQGMQQNAYSVPAQPMGAVNSEFYLPEAPQGNKLHGNINKRQERKKLYDNIRSGNFGI
The following text describes a protein:
Function:
Phosphorylates a large number of substrates in the cytoplasm and the nucleus.
Sequence:
MGNAAAKKDTEQETVNEFLAKARGDFLYRWGNPAQNTASSDQFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRILQAINFPFLVKLQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGRFSEPQACFYAAQVVLAFQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEI
The following text describes a protein:
Function:
Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Acting as a counterplayer of BIR1, promotes the activation of plant defense and cell death. Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity. Functions as an inhibitor/regulator of abscission, probably by regulating membrane trafficking during abscission.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MAVPTGSANLFLRPLILAVLSFLLLSSFVSSVEWLDIDSSDLKALQVIETELGVNSQRSSASDVNPCGRRGVFCERRHSATTGEYVLRVTRLVYRSRSLTGTISPVIGMLSELKELTLSNNQLVNAVPVDILSCKQLEVLDLRKNRFSGQIPGNFSSLSRLRILDLSSNKLSGNLNFLKNLRNLENLSVANNLFSGKIPEQIVSFHNLRFFDFSGNRYLEGPAPVMSSIKLQTSPHQTRHILAETPTSSPTNKPNNSTTSKAPKGAPKPGKLKKKKKKSKKKKVAAWILGFVVGAIGGTISGFVFSVLFKLIIQAIRGSEKPPGPSIFSPLIKKAEDLAFLENEEALASLEIIGRGGCGEVFKAELPGSNGKIIAVKKVIQPPKDADELTDEDSKFLNKKMRQIRSEINTVGHIRHRNLLPLLAHVSRPECHYLVYEYMEKGSLQDILTDVQAGNQELMWPARHKIALGIAAGLEYLHMDHNPRIIHRDLKPANVLLDDDMEARISDFGLAKAMPDAVTHITTSHVAGTVGYIAPEFYQTHKFTDKCDIYSFGVILGILVIGKLPSDEFFQHTDEMSLIKWMRNIITSENPSLAIDPKLMDQGFDEQMLLVLKIACYCTLDDPKQRPNSKDVRTMLSQIKH
The following text describes a protein:
Function:
D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.
Subcellular Localization:
Cytoplasm. Periplasm. Cell surface. Note=Low exposure on the cell surface.
Sequence:
MAWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS
The following text describes a protein:
Function:
Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism.
Sequence:
MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLDTHFAKGLKLSTVTTSGVNLSRTWQEVKGSDDAWFYTVFQLSGQAIMEQDERQVQIGAGDITLLDASRPCSLYWQESSKQISLLLPRTLLEQYFPHQKPICAERLDADLPMVQLSHRLLQESMNNPALSETESEAALQAMVCLLRPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEWIAGETGMSVRSLYRMFADKGLVVAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFSDQSHFSTVFKQRFGMTPGEYRRKFR
The following text describes a protein:
Function:
Functions as an intestinal M-cell transcytotic receptor specific of type-I-piliated bacteria that participates in the mucosal immune response toward these bacteria. At the apical membrane of M-cells it binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to elicit a mucosal immune response.
Subcellular Localization:
Zymogen granule membrane; Lipid-anchor, GPI-anchor. Secreted. Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane; Lipid-anchor, GPI-anchor. Membrane raft; Lipid-anchor, GPI-anchor. Endosome. Note=Secreted, after cleavage, in the pancreatic juice.
Domain:
Each ZP domain consists of an N-terminal (ZP-N) and C-terminal (ZP-C) region connected by a flexible linker; the linker allows the ZP domain to wrap around the ZP-C subdomain of the preceding subunit.
Sequence:
MVACDLLWLAAASCLLTLVFPSTTHQGYGNPRNTSNVDLDCGAPGSSSAGICFDPCQNHTVLNDPSRSTENTVSSEECDSHLRGWYRFVGDGGVKMPETCVNVYRCHTYAPMWLSGSHPILGDGIVNRTACANWNENCCFWSSEVQVKACLGESGEYHVYKLQGTPECSLRYCTDPSTAPKKCEIACRPEEECVFQNNSWTCVCRQDLNVSDTLSLQPLLDCGANEIKVKLDKCLLGGLGFKEDIITYLNDRNCRGTMKDEPNNWVSTTSPVVANDCGNILENNGTQAIYRNTLSLATDFIIRDFLVNVNFQCAYPLDMNVSLQTALQPIVSSLNVDVGGAGEFTVTMALFQDQSYTHPYEGSKVLLPVENILYVGALLNRGDTSRFKLLLTNCYATPSGDRNDIVKYFIIRNRCPNQRDSTINVEENGVSSESRFSVQMFMFAGNYDLVFLHCEVYLCDSTTEQCQPSCSTSRLRSSEPAIDLTRVLDIGPITKKSVQNPDTSNGTPRNTGFLLAWPTFFLPVFLAWLF
The following text describes a protein:
Function:
Common component of the spliceosome and rRNA processing machinery; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTAMEVDSGTPGGADKEKKKLYLVSPIARPLAGKKLTKKSLKLIKRAAKSKQLRRGVKEVVKALKKGQKGLCIIAGDISPIDVITHVPILCEEADVPYIYVPSKEELGAAGATKRPTSCTLVLSGPLKGDSSEEDKEKFTTEFNEVVEEVKELASSFF
The following text describes a protein:
Function:
DEAD-box RNA helicase probably involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions (By similarity).
Subcellular Localization:
Cytoplasm. Note=The RNaseJ-RhpA complex co-localizes with 70S ribosomes and polysomes; remains associated with ribosomes in the absence of RNase J.
Sequence:
MELNQPPLPTEIDGDAYHKPSFNDLGLKESVLKSVYEAGFTSPSPIQEKAIPAVLQGRDVIAQAQTGTGKTAAFALPIINNLKNNHTIEALVITPTRELAMQISDEIFKLGKHTRTKTVCVYGGQSVKKQCEFIKKNPQVMIATPGRLLDHLKNERIHKFVPKVVVLDESDEMLDMGFLDDIEEIFDYLPSEAQILLFSATMPEPIKRLADKILENPIKIHIAPSNITNTDITQRFYVINEHERAEAIMRLLDTQAPKKSIVFTRTKKEADELHQFLASKNYKSTALHGDMDQRDRRSSIMAFKKNDADVLVATDVASRGLDISGVSHVFNYHLPLNTESYIHRIGRTGRAGKKGMAITLVTPLEYKELLRMQKEIDSEIELFEIPTINENQIIKTLHDAKVSEGIISLYEQLTEIFEPSQLVLKLLSLQFETSKIGLNQQEIDAIQNPKEKTPKPSNKKTPQHERARSFKKGQHRDRHPKTNHYSKKPKRR
The following text describes a protein:
Function:
Protease that is part of the quality control system in the inner membrane of mitochondria. Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OXA1 and COX1. Cleaves and thereby promotes the turnover of mistranslated or misfolded membrane proteins. Cleaves the misfolded multi-pass membrane protein OXA1. Involved in quality control of cytochrome oxidase assembly: mediates the cleavage of COX1 in cells lacking COA2. Required for the stability of the respiratory supercomplexes. Required for TOR signaling.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MLRNIIRFKGFGKGTSGGFLKPVSFRVQLTRCYRYDNGPSYRRFNNGEYSQKSSFKSILLDKSSRKYLALLFGGCSLFYYTHLDKAPVSDRSRFIWVSRPLELTIGNYTYKSIWRQTQQEILPPQHPLSIKIENIFMKIVEAAYKDPSVDNSLLDGIKWEIHVVNDPTASPNAFVLPGGKVFIFSSILPICANDDGIATVLAHEFAHQLARHTAENLSKAPIYSLLGLVLYTVTGAHAINNILLDGFLRMPASRQMETEADYIGLMIMSRACFQPQESIKVWERMANFEKQMNRGGVVNMEFLSTHPASTRRIENMSKWLPKANEIYEQSDCSSMGNYYKSFFSM
The following text describes a protein:
Function:
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
Sequence:
MSCFYLDLLKIKDPSFMKRLDIQELEALAADIRAFLITSTSKSGGHIGPNLGVVELTIALHYSFNSPKDKFIWDVGHQSYVHKILTGRANQFGTLREHGGLDGFPKRKESIHDVFETGHSSTSLSAAAGMVIARDIKKEDFYVIPIIGDGALTGGMALEALNHIGDMGKDMIVILNDNDMSIAPNVGAIHNILGKLRTSDTSKQTKTNVDGAFFEELGFMYLGPIDGHDIEEVITNLELAKRAKGPVLLHIVTKKGKGYQPAELDSRGTWHGTGPYKVETGSFIKPAKRAASWSSVISNELIRLAEMDERIVAITPAMPVGSKLEKFAKAFPERFFDVGIAEQHATTMAAGLATQGMKPFLAIYSTFLQRAYDQLVHDVCRQKLNVVIGIDRAGLVGADGETHQGIFDISFLNSIPNMTISMPKDEVEARQLMDTAFSYNDGPFAIRYPRGEAPGVQVVESNTLIPIGQWETIIQPLDAVILTFGPTIELALKAAEQLEIEGYRVGVINARYIKPLDEALLHKILKQKIPILTVEESLLKGGFGASVLEFIEANNYRDVIMHRIGLPDEFISHGSVSIILESFGISTTGLVLKIKEMLAQSGKLRAKRL
The following text describes a protein:
Function:
Plays a role in cilia formation and/or maintenance. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Involved in DNA damage repair (By similarity).
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Mitochondrion. Cell projection, cilium, photoreceptor outer segment. Cytoplasm. Note=Localized to the connecting cilium of the cone and rod photoreceptors. Colocalizes with NEK1 and SPATA7 at the basal body (By similarity).
Sequence:
MKLTRKMVLSRAKASELHNVRKLNCWGSQLTDISICREMPSLEVITLSVNSVSTLEPVRSCRRLSELYLRRNRIPSLNELFYLKDLPHLRVLWLAENPCCGTSPHLYRMTVLRNLPHLQKLDNQAVTEEELTRALMEGDEITAAPHREGAGNGCPKPPYALNSVSSATETSQHLLSYTEETEVQGQTTTDQSPSFSPRDTMRSHKNRNILTAILLLLRELDTEGLETVQQTVGSRLQALHRPEPQEDME
The following text describes a protein:
Function:
A flexible structure which links the flagellar filament to the drive apparatus in the basal body.
Subcellular Localization:
Bacterial flagellum basal body.
Sequence:
MGIFDAMNTSVGGLQAQSYALQNISGNIANSSTTGYKGIGTSFVDLIPDASVPSKQVAGGVTANAKATITTQGTISSSSVATNMAITGDGFFSIQKATSVVDNLPQFGGVTYYTRRGDFQLNSNGNLVNGAGYYLMGVTVDPKTGNPQGNVATVLKFQNNFIPAQATTSIQYAANLPTQPNTAASSTAASKTLLAAGGLNPSDFQANPLPVGTPPAPYTSATVSGAAATGNIRSAYSSTTGTGTVPLQNNSSAVASTSTSLDNTVGTHLASSILTALSGQVLTINGSNTITFNGGTTVSTVGNNTTIGLGAGTTATVASILNAIQTAGGAGVTASLSASGNIQISTGTGTDVSIGSGTAATALGISSVTRGGNVLSSPALTGATVLSGSATAGGAEVLSSGFSAGPPADTITVNGQTLTFMASGASGPNQINITDNITTLLGKIDALSGASGSSISPGGVITLNTGTVSNLSVSSSNSAAFAALGFTSTITKNRDGGGTAGTGGVIGNDIATFTKESISGGAVTAYNAAGTPVNLQLRWAKTDSASLGTGHSDTWNLFYQTDPNATGTTVGWVNTGQAFTFAADGSLTSPSGSGITINNVSVGGQALGSVAFNISSGGLTQYASTSGAVTINTITQNGYAAGQLRSVAVNNNGLVVGTFSNGQNLDLAQVSLSHFNGTNYLKALDGGAYAATEQSGPAIDGASGTISGSSLEGSNTDIADEFTKLIVTQQAYSANTKVITTANSMVQDLLNVLR
The following text describes a protein:
Function:
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
Subcellular Localization:
Nucleus.
Sequence:
MTSVAQRQAQPAQPSTSQTAAPTRTQTETSSPAILRLRGAHSNGRSVQWRSDVVDNEGLGRKKSKVCCIYHRPKGVDESSDDSSSSSDSSSSSDSDSDPEPDQDKRITSGGGSSGRGHRHSHDHDHDGREGGCNHDHGRGRKHGNKGKKTERRPSPNAYEKMPKYKPKDGGAGPSNSETQGPGGSK
The following text describes a protein:
Function:
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
Subcellular Localization:
Mitochondrion. Cytoplasm. Nucleus.
Sequence:
MNIFNYTTLIFRRLSSTFKASNKASIEWKKQNIAVKRKIGGYWNPKKKLPLESMDEIRRLKKEKSSMSCSELAKLYGVSPESIRRILKSSNRPLDDREKSRKEKRWLNSLKSNRDFA
The following text describes a protein:
Function:
Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA. Does not bind fatty acids (By similarity). Plays a role in protein N-myristoylation (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MTDAQIENKFKLAVDYITNNSGKLSNIKNEEQLYLYCNYKQATIGDCNTKAPPFYDYIGKSKWNSWNSLKGVEKIVAMNSYISLVNALSPGWDSNIKVERATQSVFLNDEEFKELEKKEKEEKEELKKLEEENGGEIEKPKSKWMGPVLSKFSLVDDETLEKLEKNTKQDLGYWVSVNDIERVKKEIENDKNIINEVDEDGRTALIWACDRGYFEIAKLLIENGSNVNVQDGEGMTPLHYAVVCDQFEICKLLLSQSSIDKSIKDNSDSIPSDFIDSSTSENIKSLFK