lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, rpn-6.1 is required for proteasome assembly. Plays a key role in increased proteasome activity in response to proteotoxic stress: induced by daf-16, promoting enhanced assembly of the 26S proteasome and higher proteasome activity, leading to extended lifespan.
Sequence:
MRETSSREDTNNIGKAPEMSGGTIMDTMTSLPHQNDQNVIRHLTNLVKSPASGDDDIKKKEDSIMELGNILAQNKQTEELRNMIEQTRPFLVSLGKAKAAKLVRDLVDLCLKIDDQDGDIKVGLVKECIQWATEQNRTFLRQTLTARLVRLYNDLQRYTQALPLAADLIRELKKVDDKDVLVEVELEESKAYYNLSNIGRARASLTGARTTANAIYVNPRMQAALDLQSGILHAADEKDFKTAFSYFYEAFEGYDSVDEKVSALTALKYMLLCKVMLDLPDEVNSLLSAKLALKYNGSDLDAMKAIAAAAQKRSLKDFQVAFGSFPQELQMDPVVRKHFHSLSERMLEKDLCRIIEPYSFVQIEHVAQQIGIDRSKVEKKLSQMILDQKLSGSLDQGEGMLIVFEIAVPDEAYQTALDTIHAMGEVVDALYSNASKIN
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRWNGCRYRYKTDQTPQRRVEKNFIRRHCPTKTMVIKESEFDDSLGYALLRRDMGTVWDTAKDERMVNGTMDPELIQRAKERAVRAQLNSADGDTCETHDQFYRDHKLLLVLFRGLAVMPITRSVPGRITFSWRSAASIYAFCFYLVSTVIVLVVGYERIKVFQTTTKFDEYIYGILFVIFLVPHFWIPFVGWGVAKQVAIYKTMWGAFQVRYYRVTGTSLQFPHLKLLIVFLSIGCLVCAIVFLLSLSFLLEGFALWHTSAYYHIITMLNMNSALWYINSRGIRVASSSLSRCFRQDVAIECTAAMISRYRFLWLNLSELLQALGNAYARTYSTYCLFMFVNITVAIYGALSEIIDHGFGFSFKEIGLIVDTVYCSTLLFIFCDCSHNATLQVAQGVQDTLLSINLLKVDQPTQKEIDLFIQAIEMNPAIVSLKGYAEVNRELLTSSIATIAIYLIVLLQFKLSLISQQIPVEIIENVKLLQKQ
The following text describes a protein:
Function:
Component of the minor spliceosome that promotes splicing of a specific, rare minor intron subtype. Negative regulator of centrosome duplication. Constrains centriole number by modulating the degradation of the centrosome-duplication-associated protein SASS6 in an acetylation-dependent manner. SIRT1 deacetylates CENATAC in G1 phase, allowing for SASS6 accumulation on the centrosome and subsequent procentriole assembly. The CENATAC acetylation level is restored in mitosis by NAT10, promoting SASS6 proteasome degradation by facilitating SASS6 binding to APC/C E3 ubiquitin-protein ligase complex/FZR1.
Sequence:
MAPPQRCPLCRQTFFCGRGHVYSHKHQRQLKGALERLLPQVEAARRAVRAAQVERYVPEHDRCCWCPCCGCEVRKHLSHGNLTVLHGGLLEHLASPEHKKATNKFWWENKANAQMKEKFLISPQDYARFKKSMVKGLDSYEEKEDEVIKEMAAQIREVEQSRQEVVRSVLEPQAESDPEEGSSAPESWKATNGHVASSSQQVSHLALQPVAELDWMETGQQLTFIGHQDTPGIGNIHSGATPPWMIQEEEHSSGSLPIGPSYEEFLKEKEKQKLKKLPPDRVGANFDHSSNTSAGWLPSFGRVWNNGRRWQSRHQFKTEAATRSKQPRKGKS
The following text describes a protein:
Function:
Transports purine nucleosides. Shows a broad specificity for purine nuclesides, including adenosine, 2-deoxyadenosine, guanosine and inosine. Uptake of purine nucleosides may support growth under nitrogen-limiting conditions. It also exhibits specificity for the uptake of certain sulfonamides, which are structural analogs of para-aminobenzoic acid (PABA). Was originally identified as a putative arabinose efflux transporter, however, overexpression of the gene has no effect on intracellular arabinose concentrations.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFAAIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
The following text describes a protein:
Function:
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MSFQCVKKYEDSYDKYVLAATSEKVVLPDYLDKESKKIAETIIKKNKFTAKASEKISMTLVNKKKVIEFIIIGLGEKKKLDAKNTRQYLFDGLKNIIGKVLFSFDNKDLDNIDILAEVVEHINYKFDKYFSKKKEEFLEVSYLTDKKVPKLIEGYELAKISNIVKDLVNEQAEVLNPKELADRATKLGKKFGFDVEILDEKKAQKLGMNAYLSVARAAHHRPYVIVMRYKGNAKSKYTFGLVGKGLTYDTGGLSLKPTDSMLTMRCDMGGAATMIGAMCSVAKMKLKKNVTCVVAACENSIGPNAYRPGDILTAMNGKTIEVTNTDAEGRLTLADALTYIVRKEKVNEVIDAATLTGAIMVALGEDVTGVFTNDEKMARKVIDASENWNEYFWQMPMFDLYKKNLKSSYADMQNTGVRWGGSTNAAKFLEEFIDDTKWVHLDIAGTAWASGANPYYSQKGATGQVFRTVYSYIKDNKN
The following text describes a protein:
Function:
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
Subcellular Localization:
Cytoplasm. Nucleus. Secreted.
Sequence:
MLNKYDYERGSIFISSLKMHRQNSTGKKNKKIKNFRSLSKSLILCNAKNSDDGSSLEEKYTEITDTPHSIVRDSDSLTTDTFQIASMIPDPMIRKIIVSKATSADPTPSKPSLMEPNYFLEFKTELDNPCPLKMKARCTRTRSNSTSVNPYWIGEIDPPLTKRPTNCREIQSANLYSNRKSMSQQLDCLSGGVQSVSQPSRSLSTAQLINTRSLQASMISNIILMKGQGKGLGFSIVGGKDSIYGPVGIYVKTIFPEGTAAADGRLQEGDEILELNGESMYGLTHNDALQKFKQVKKGVLTLTVRTGLGALEEKAGYFASQMFRSKSSSCCVAREHSPLQSESHAFLLSSHNPNDRVLMEVAMHKESGVGLGIGLCSIPNCGGISTIFIHSLSPGSVAHMDGRLRAGDEIVEINESVVSNKSLNEVYALLSHCPSGPVTILISRHPDPQISEKQLKNAISQAVENSRCEKDPHSWSYEGERRFFSCFHGKYQCESCIGRHASYLYNSRRGQKKMVRSSSEGSYSPVSLGPNMNSYQSHTVASRVHSVNVPLGTEPAVLHYSTPVSRVENHSPDHPEGLSGSQSSYKKSNGHSGEILVKKLTTKPIPPPRKYYKEDLKEDINHCEEKGQSVDETGNLQLKGNQQMTSKSILDTSSSTSGCSYTSAAEPDKHPDTGNPVSNRRPLLRRQAPVDYSFDTTSEDPWVRISDCIKNLFSPLINEGQNLMDLESSISTAGGNTEKLRRDSACEDSQMCSPQEMSNYKKGPPVAPKPTWFRQSLKGYKNVDKQPTDSTSMDKYKEIHNNVKPQTSSRTSSIKQKINSFETFSTPPPVGKISDRGNVTSSAPNDKPFNKQEVESVTVCLNNVTVSPAEIPEAIQPHLAIPKSPEKKEPELSQSPPKSCFQGMRRSSSTSNEPQFLSSEFSELIPCKTLSQRSRSFPLGATTPSDVLKTNENNSKIYSISNQVSSALMKSLLCFPQSPQLQVTNPWQSESYLVDEVPSSPKTESHHLDTGFSVNLSELREYGAGQPEKEKEEDVREQSLALHSVPAGQSVISLLPREELTALIEEVKGLDEETLKQFDDIHVVVLHKEEDTGLGFSLAGGLDLENKTITVHRVFPTGLTAQEGTIQKGDKVLSINGKSLKEVTHNDALAILRQARDNRQAVIVIKKGNDGEQPAESLDSAFSALTDDSTATNSDDTGDIVVVTLEKSLAGLGFSLDGGKGSVQGDRPVIINRIFKGVSEKNNAVQSGDELLQLGNISLQGLTRFEAWNAIKTLPSGLVQAVIRRKSPYSTVNQ
The following text describes a protein:
Function:
Elongator complex-associated factor that is not a structural subunit but rather transiently contacts the complex. Regulates both meristem activity and organ growth; acts as a positive regulator of adaxial leaf patterning. Required for an early step in synthesis of 5-carbamoylmethyl (ncm5) groups present on uridines (ncm5U) at the wobble position in tRNA.
Sequence:
MALVVMCGQPCSGKSEAAACLAAALRSSVLDVTVRVIDESSLHLGRDESYKDMVVEKNLRGVLRSEVDRSVSRDGIIIVDSLNNIKGYRYELWCLARASGIRYRVFFCDTEVDHCRDWNVKRQEKGEPSYDSNIFEDLARRFERPDSRSRWDSPLFELFPSREEIVESSPVIAEAVSYLTKKVDSKTRDVKVLQPTIATQSVRTTEGNSLYEMDKATQEVVSAIVEAQSGGLGLAMNKISLGPDLPTINLRRPVGLPELRSLRRTFIKLAGQYSLSGRPPPTDADSAKRMFVDYLNREIGG
The following text describes a protein:
Function:
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.
Sequence:
MAAPCRDLTGLRRGLAAARLAPGRRGANKLCLAPFHHRAPPPQQQQGRRRQRQGLKVVAAISEDLPRLAAPGTGKGAPEGRRPEKVLVRAALTVRRKHKEDLKEALAGHLDALWDMVGRSVALELISTKIHPRTKKPLHSGQASIKDWCQKRGVKGEHVVYTAEFMVDSDFGEPGAITVANRHHREFFLESIVVEGGLPCGPVHFACNSWVQSTRELPGKRVFFSNKPYLPSETPPGLRELRDKELKDLRGDGTGVRKLSDRIYDYATYNDLGNPDRGKEFIRPILGGDNIPYPRRCRTGRPPTDTNMLAESRVEKPHRIYVPRDEAFEELKQGAFSSGRLRAVLHTLIPSMIATISAETHSFQGFHHVDNLYKEGLRLKLGLQEHLFQKIPLVQKIQESSEGMLRYDTPRILSKDKFAWLRDDEFARQTVAGINPVSITRLTVFPPVSKMDPAIYGPPESSITEAHITGQLNGLTVQQAVDEAKLFILDYHDVYMPFLDRINAIEGRKAYATRTILFLTKAGTLKPIAIELSLPPSKAGEPRPSKVLTPPADATSNWLWMLAKAHVSSNDAGVHQLVNHWLRTHAVMEPFILAAHRRMSAMHPVFKLLHPHMRYTLEINALARQSLISADGVIESCFTPGPVSFEISAAYYRDHWRFDLEGLPSDLVRRHSCRCPIPVCSCLFLPLSTDISSSLVIRRVAVEDASQPHGIRLLIEDYPYANDGLLLWSAIRSWVESYVQLYYPDAGTVQSDDELQGWYHETVHVGHADIRHAPWWPSLSTPGDLASILTTLVWLASAQHAALNFGQYPLGGYVPNRPPLMRRLLPDPERDAAEYATFMADPHRFFLNAMPGVLEATKFMAVVDTLSTHSPDEEYLGEERDEPWTGDAAAVAAHDMFTADVRRAEEAIDSRNADQRRKNRCGAGVLPYELLAPSSPPGVTCRGVPNSISI
The following text describes a protein:
Function:
Involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond. Involved in cell wall biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSEVSPQSQYGGEPDKPTTKSSSWLRNLSRSNLAALILFYVASLHVIGLYVFTQGFLLSRLAIPHVSPAYNVSNPSPISATHSKAVIIVIDALRTDFISPYHPQPPSPHHHGVLSLPAELTQSRPEHSLIFNSFSDPPTSTMQRIKGITTGSLPTFIDIGSNFASAAIEEDSLVSQLVAANKRVGFMGDDTWMNLFPSSFHPNMSHPYDSFNVEDLHTVDNSVITHLFPYLHPSNQSQWDVLIGHFLGVDHVGHRVGPHRDTMTEKLTQMNEVLEKVVDLIDEETLLVVLGDHGMDDKGNHGGDSEMETSSALWLYSKGPMLTNPAVVQDKDTSAIFKSLPTYIFPKSTMPLRQINQIDIVPTLALLLGVPIPYNNLGSVIPECFTNNLETLEVAQRVTADGIWRYVEAYGDKEVKENLNSAWRHAQSQYQKDNLSASIIAHRAFSLDALVHLRSLWAQFSMPLIVIGSLILGLCALTLIALYVGVRNNGVNWDVYARLALETATMGSTVLASIAGTVAGVYTARPIVAIKVFIVAAALISEVILILPLFVKSSLSLALPLPTSFSINRHIGPFILIVHALSFASNSFIMWEDRVVLYLISTIPIIYIIRALSAPTADMRLKIIFLSLAFTILSRLAGTITICREEQQPYCSVTFFSGVTATAPTWALIAIVPLALQIPRAIGITLSRSKSLAGPAPFILGILWRAVLVANSVYWVLEFFESFDGLNPARIPLVNFLKLWLARCSAGASLGAIPYVWLTSPLCISVERTTDQATGEEEVTVFGFANAFGSTYILYTLAPFALIHLVSQPMAQFTLTAFLIGLLVYLELVDTRRDAIILTTSFASLGNNKNNNNASSPAGLASFDPADTAQTIVRPSFTDVVPIALSGFLTFFATGHQAVISSIQWKSAFVGFSTASYLFSPVLVVLNTWGGFFLSAIAVPLLAIWNIAPRPRESIPTLAHALQVTLAFLVYHTVVAFASAITAAWLRRHLMVWKVFAPRFMMAGVTLLVVDVGLALGLFGVRVTGWKVKKTFGCESI
The following text describes a protein:
Function:
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGIPLRIDARSTALVAVGGAVGAVLRYTVAQAIAGPLGTLAANAAGSLALGALAYEAAATDSVLSADAHTLLGTGCLSAFTTYSTFAVQTAGLAPRWMAANVATTYALGFAGVLVGRAIAATARGDRR
The following text describes a protein:
Function:
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAVQLVLNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLVIIFLIELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRTKIYIHAIDFSTKEQEVESIKTSLEKIVREVGEI
The following text describes a protein:
Function:
Component of the Golgi/endosome-localized DSC E3 ubiquitin ligase complex involved in the targeting of the DSC complex to the Golgi apparatus and endosome membranes via the AP3 pathway to ubiquinate Golgi/endosome membrane proteins. Competes with VLD1 to determine the subcellular localizations of the DSC complex. May be required for cell cycle progression.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Sequence:
MDNFESTAEGNLSIGNKRVYELRKRNFQRNLVNNLSFLGYVLISLEYIKYDRTVWTLITRAIVQSLISSPFPSDAKLRRLATLGADNNTTGVATLPGGRSIRFPGMFGTEMLYNSSSEAEQQDHDDTAIVSMKKQIRKFLFHGCLSLNMLFIILTILFPIDFFEPLSGSEPVDDGPKNTPSPFSNSDGLLLGERRGGLFLQMIGERLPKSNFSGNLGLVMFEFSILIVQFTLFSLTCVVLADLDFEEPERLEPVNSDGYDGSVIVARIPLNKTMNAILNDGNINDNNENASNSV
The following text describes a protein:
Function:
Plays an important role in the control of DNA replication and the maintenance of replication fork stability.
Subcellular Localization:
Nucleus.
Sequence:
MSDQEVDDIFGEYEKTSYSAEENDSNSKNGEVDADNGKRGKKSETTKTRKLVRSQQLKLDPNRVCGPRGITAVIQNFKNVKLQGKGHEKSDLETVLSQMEHWAHRLFPKLPFDDCIESVAKLGNNKSVQVYMKRFRMGMLDTEQEIEETLVNTDAQFDNITERGTDVFSTVVSRPSQSVTHISEDQQSRMAENKRKAEEKRKSRFMLNTSNLNDTCSNESFTSKILPELNTTVGTVISETTAETTAETNENNSEILDIDMFLENLP
The following text describes a protein:
Function:
Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism; The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MFRAAAPGQLRRAASLLRFQSTLVIAEHANDSLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCKVAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDAAATSGGSASSEKASSTSPVEISEWLDQKLTKSDRPELTGAKVVVSGDGVSLLLPRLECNGTISAHRHLHLPGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK
The following text describes a protein:
Function:
Involved in the regulation of secreted ferrichrome-type siderophores. Acts directly or indirectly to repress the biosynthesis of siderophores.
Subcellular Localization:
Nucleus.
Sequence:
MALPPVKIASRPASPTPSHHHQQAAAASSSSSSSSSHHPPPRIAARPIAPADRSPERVSQHSRGASVHDADSLPPIRPRGSRPSSPSGHAADRAPSSHHNASSTATVPARSTARSLFRDPRTLHPAGRSQSPIAAFRNRSQSSERSRLGPSRSQPNSPLLQSSSLRHHSDATGVHLPPISSLSKELVSDHPDCFAHRRRTPTTSPRATARLHMGNTFRDSSPAASSGSPATMRHDHLAYRHEHSAEEHAKMQRYSDEHPRAMNPTSRASYEHESRGMPYRDSYSAPSRAIEASYHANGARPVHHADSSTNSPQYVPGDVYEHEGSGSPPAAHHAGMRCSNCGVTSTPLWRRAPDGSTICNACGLYIKSHSTHRSASNRLSGSDASPPTHEAKLAAAGPSCSREDDPKSGSCPGDGLCNGTGGTASCSGCPAYNNNLSHALKVSKRESQTSEDPPPARTAERAPPVAEEKMDDDKSVVGALRCTNCQTTTTPLWRRDEDGNNICNACGLYHKLHGTHRPIGMKKSVIKRRKRIPANATAQPTHILDVIPVQMNANGQPVIAPAAGRNAGDSTPKSTESRRASKKSSLTSEQAMREARDREAAMLLMEVGAGARSRNSAQEDDRIHQNGALATSTSFHHDFHSARAGADTARTSHPDDSRSSKRPRQSYPLAPREAYDERDVSAIASPPAYNETHAAGATRSQRSQRSPVDAPLTDRLGRSELHGESSHGTSNAPEHAARASASDGARLGSVVPHHHHHHHHHHANHASHAVHHGHHHHHHHPVTVSASSHGHAGQAPSGMTKLSEVERLRDELLFERRRIDEVLRRAEAILASARAGNFHVEAAGPSTSGLRNGHEASHESPPTGSAQGSPGADARGTRSGHDSIKQEAPDAAPRRSKAFSNSSSSSEKDELESPPPSAHQQLASQPLVAATGAQPASRRNSFEQRMASLPVMAAVPLKRSSPPSTVSNPADNRPLSIAPQPARKATAWGIDTRSTPAASPRSGEKRARADEMDEDDDHWNWDNLYGKAKLEKAGDWRGFARPVEDRRSQSKSNGVTRRESSSTPIAARLPVASSPSQAVSAPRT
The following text describes a protein:
Function:
Constitutes the major component of lipophorin, which mediates transport for various types of lipids in hemolymph. Acts by forming lipoprotein particles that bind lipoproteins and lipids (By similarity).
Subcellular Localization:
Secreted. Note=Secreted into hemolymph.
Sequence:
SVKSEVDNFDKHLKAESAPFNNE
The following text describes a protein:
Function:
Dispensable for both meiotic and mitotic cell cycle progression. Required with SGO1 for full protection of centromeric cohesion during anaphase I. Required to prevent precocious release of pericentromeric cohesins during meiosis. Acts redundantly to SGO1.
Miscellaneous:
MISCELLANEOUS: Shugoshin is Japanese for guardian spirit; MISCELLANEOUS: Knock-down mutants show no meiotic or vegetative defects and no reduced fertility. Sgo1 and sgo2 double mutants are almost completely sterile and show a premature separation of sister chromatids at anaphase I.
Sequence:
MVLTEMSLDYSNRVLGSQKDNVKQMDKEETQQKENMLFSSQEYAAKLQKENMTLMKALAHRNKLVELSGIEIQKLRINLRSVQEKNLQLAQANSQMLAELNTNRDRLKDLQHELGCKNALLKVKKHLEEQVLPRTHHESKDKVSASASDGDCKSFQVHDIKHKDTKRKRTTRIKSSVSADVKPIPVNDSNSKANRKRRVSGVIDTTGIPEEICQTEDDIDKGVVSRGVNQDIDNVVNKKFVPDAANPVKESVHRKRQCTRRQSTRFDVQETKQTEKLLEMDGAKESKETASFSLRRRSARLRHEEAEPCKSLHEGDEVRETIKRRRVSLRLSARFDIQEPHVTETSNADDARSIVIEESAGSRSESVEPSESRHETKEITRKRSFSTRRQSTKGKSQTDEAIKEIATDPSLVNTIVQECDQETESKDKPKADENEGMTRRSSVGRPSRHAAEKVQSYREVSLRVKMRRKC
The following text describes a protein:
Function:
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Sequence:
MHEWSLAEAILEGLTSLMKQEGMKKVSEVEILYGEMMELELDILKFALEELSKETPMKDTKFIFSEERASFRCNSCGYRWNFEQAHSSLSEELGIRELAGERESPIHFIPELAQALMRCPNCGSRDFEIESGKGIRISRIVFEG
The following text describes a protein:
Function:
GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.
Subcellular Localization:
Mitochondrion.
Sequence:
MIKRLFCSINKNKIINEPPKLSIIKDTIYNLSSGVGKSGVAIIRVSGPQAETVIRKLIKKSDVDKNEEIKSRYATLSTFYNPKTNEQLDKGMFIWFPSPNSFTGEDVVEFHIHGGRAVIYETMEAIGLIEGTRPSEQGEFTKRAFENGKMDLTQVEGLSDLLDASTSFQKKIALKQMQGSISEFYLSLRKDLIRASAYMEAFIDFGDDAELDPEIVDQSRNRIISIRDKIQQHLNDGKRGERLRDGANIAIVGPPNAGKSSLINLLTNRKASIVSPIAGTTRDIVEVILDIDGYPVIIGDTAGLRNSTNDQIEIEGIEMAKDRFNNSDIKLFLFDSFNLFSQLNQNQNLNSSFNFNEEIKNLFNFIDNETIIIFNKSDLLKQFDNLKEWENLKLNLLDNIKKSNNLNSIQSIEISCNNNENIKDLLNLLKLNLKNLFEIQDKESPLLTRLRYKQHLSDCVESLDRYLYYCEHDVVLASEELRSAILSISEITHSVNIDDLLDIIFKDFCIGK
The following text describes a protein:
Function:
Essential component of some SCF-type E3 ligase complex that positively regulates the gibberellin signaling pathway. Upon gibberellin treatment, the complex mediates the ubiquitination and subsequent degradation of DELLA protein SLR1, a repressor of the gibberellin pathway, leading to activate the pathway.
Subcellular Localization:
Nucleus.
Sequence:
MKFRSDSSGGDEPRAPAAGDGGGGGDEPAKRQRTDPSSSSSQGEASSSSQPPPQQQQEEQPPEDAGEGEQPRVPDLGEDLVFEVLRRAEARTLAAAACVSRGWRQLAEDERLWEAACVREWANLGFSERQLRAVVLSLGGFRRLHAVYIRPLQWRGAGVPRQQGRRQPPVRLGRDQVQLSLSLFSIGFFQNMPCPKKDKGNDSDKNGGGQCG
The following text describes a protein:
Function:
Inhibits zinc finger homeodomain (ZHD) transcription factors by interacting with them to prevent both their nuclear localization and their DNA-binding properties. Involved in integrating signals from multiple hormones by regulating the expression of specific genes.
Subcellular Localization:
Cytoplasm.
Sequence:
MRKRQVVLRRASPEEPSRSSSTASSLTVRTVRYGECQKNHAAAVGGYAVDGCREFMASRGEEGTVAALTCAACGCHRSFHRREIETEVVCDCNSPPSTGN
The following text describes a protein:
Function:
Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
Subcellular Localization:
Cytoplasm.
Domain:
ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site; The C-terminal coiled-coil domain is crucial for aminoacylation activity.
Sequence:
MKDKFSFQKNYDFNLVSDGLYEIWNNAGFFKPKDKNNSFTAILPPPNLTGTLHIGHAFEVSITDQIMRFKKMQGFSINWIPGFDHAGIATQTKYEKIALKENQKYFDADDDKKSEMIMNWALNQSEIIKNQLKSLGVCLNWSETKFTLSEQANKIVNNCFKNLYENGFIYQAYTLVNWDTKLNTAISNIEVINKPVNQHLHYVVYKLANDSKQELIVATTRPETIFADVCLLVNPKDKRYTNFWNKLVVNPLTGKQIPVVTDSYVDIKFGTGILKCTPAHDFNDYEINTKYKFDFLSCIDSNGILNQNASKFQGLSVLQARNKIVKWLEKNKLLVKSIPLTSNVGFSERSGTVVEPMLSKQWFVDLPKLKDHLYLKKYPDFIPKRFNKQVSNWLNKLKPWCISRQLIWGHKIPVWFENNTGEIVVGEKPSKNLQNYTRSKDVLDTWFSSSLWPLICLNWEQDDSFHETELLVTGYDILFFWVLRMLFNSFFETKKLPFKTVLIHGLVRDEQNRKMSKSLNNGIDPVDLIRNYGADAVRLFLCSNHTPGDDLIFSEQKIKSAWNFLNKLWNVTKFVIQLENDQEISYDLDKLSLSETWILAKLDKVIQKITKLLDKFQLALANQILVKFVWDDFCNTFIEAIKKEPNQLKPQLFYTAKSVLSNIAILLSITVPFLSERIYQQFNNKSVMQATWPLATKIKIPKLFDLVLAAINDLRNYRKQYMLNSQQKLVVILSGKNAVDVKQYFNFSWIELKIETNKKVSFKYQIVDDTTQRLKSLQKQQAFFESEVKRSQAIVKNKSFLEKAPKEKVKSEFLKLEEYQKKLTETNQLIAKLTKAH
The following text describes a protein:
Function:
Required for nicotinamide riboside transport across the inner membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTDLWLTLVNSVNAALGEVHVMTAWEALAVVLAMAYLLLAMKASVWCWAAAFTSTAIYTVLFWKVALLMESMLNIYYMGMALYGYWLWTQGGDKHQGVKVTTWPLKTHLKLIAATTLVSLGIGHGMATFTQASFPYLDAATTCFAVMTTYLVAKKVLENWLYWVVIDLVSIYLYLSKGLMLTSLLFVLYVGLAVVGYFLWRTALAESRLNLNGERAAKLLG
The following text describes a protein:
Function:
Has antifungal activity against A.niger (MIC=2.1 uM), C.albicans (MIC=8.5 uM), C.fructus (MIC=8.5 uM), F.oxysporum (MIC=16.9 uM), P.pastoris (MIC=16.9 uM), P.tannophilus (MIC=8.5 uM), T.harzianum (MIC=4.2 uM), and Z.marxianus (MIC=8.5 uM). Lacks antibacterial activity against the Gram-positive bacteria L.monocytogenes, M.luteus, S.aureus, and S.lutea, and the Gram-negative bacteria E.coli D31, E.coli ATCC 25922, and S.typhimurium.
Subcellular Localization:
Secreted. Note=Secreted in the hemolymph.
Sequence:
MAKNFQSVLLLVCLSFLVIVSSPQNAVQADTLIGSCVWGATNYTSDCNAECKRRGYKGGHCGSFLNVNCWCE
The following text describes a protein:
Function:
Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity). Functions as a thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds.
Subcellular Localization:
Cytoplasm.
Sequence:
MEGKVYIGGEDYEKEFTPKDYLTTYYSFHSGPVAEQEIVKFSLQNLYQTFSTGGVGGDVLIDIGSGPTIYQLLSACEVFREIIVTDYTPQNLQELQKWLKKEPGAYDWSSIVQHACELEGDRSRWQEKEAKLRRTVTRVLRCDVTKTPPLGSAQVPLADCVLTFLAMECACPDIDTYRAALRRLAGLLKPGGHLVTLVTLRFQHYMVGPKKFSGVYLEKEVVEKAIQDAGCQVLKCNCVSLSYSEAYCSHDGLCFVVARKGPSA
The following text describes a protein:
Function:
Has growth inhibitory activity.
Subcellular Localization:
Secreted.
Sequence:
MGKEHLFGRRLFLGALCILLLLLETGLARNLWKRALHLKLKEKYDDYEYPLHPHSAHSQKNDRCPPPPETLPDQACEVPGCQSDSECERHRRCCYNGCIYACLESVQPPPVLDWLVQPKPRWLGGNGWLLDGPEEVLQAEACSTTEDGDEPLHCPTGYECHIINPGNAAEGIPNRGQCIKQRGNSGGFCMKTVLPLASPALLPFLHAYFRDP
The following text describes a protein:
Function:
Histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, possibly by contributing to the maintenance of proper higher-order structure of DNA and chromosome condensation during mitosis.
Subcellular Localization:
Nucleus. Chromosome. Note=Specifically localizes to mitotic chromosomes. Associates to chromatin-dense and transcriptionally silent euchromatic regions.
Sequence:
MIMVRRRQRPAKEAASSSSGGASSGSGIPVDQALPLNVAGNLLEDQYFASPKRKDCRLMKVTQNGQLPEATMMAHNKDNKAGRTIGVPLATRSQTRTIENFFKANAAAKDSQKTIHTEEQLNLGNQELKLDDEELNGQIKLDDEVLKLADKQINENLPFADEVDAKAEQKLMDEELQQVVEELLFDGSSRASSNSPFYQHDMDVMQEIQQTPEIPHIKKVTEPLEGLGSLADFQTHRSALRDSHSSTHSSSTDNIFLQEPVLTLDIDRTPTKASSIKINRSFELAGAVFSSPPSVLNACLNGRFNQIVSLNGQKEALDLPHFDLDQHDSSSCDSGVACGLTANTESPAGQPRRRKPATPHRILCPSPIKTALKVTGGICKVGSADPLSPRKSPRKLPTTTAAVAACKSRRRLNQPKPQAPYQPQLQKPPSQQQQQQQDDIVVVLDDDDDEGDDEDDVRALIKAAEERENQNKAPATANSNKAGMKTMLKPAPVKSKTKSKGPTKGQPPLPLAATNGNREMTDFFPVRRSVRKTKTAVKEEWMRGLEQAVLEERCDGLQVRHFMGKGRGVVADRPFKRNEFVVEYVGDLISIGEAAEREKRYALDENAGCYMYYFKHKSQQYCIDATVDTGKLGRLINHSRAGNLMTKVVLIKQRPHLVLLAKDDIEPGEELTYDYGDRSKESLLHHPWLAF
The following text describes a protein:
Function:
Component of the mitochondrial large ribosomal subunit (mt-LSU). Within the mitochondrial ribosomes, required to direct the nascent polypeptide toward the tunnel exit and position the exit at a distance from the membrane surface.
Subcellular Localization:
Mitochondrion.
Sequence:
MAAPIPQGFSCLSRVLGWWSRQPVLVTQSSAIVPVRTKKRFTPPIYQPKFKTEKEFMQHARKAGLVIPPEKSDRSIHLACTAGIFDAYVPPEGDARISSLSKEGLIERTERMKKTMASQVSSDHDRLHTLVTEHCFPDMTWDIKYKTVRWSFVESLEPSHVVQVRCSSMMNQGNVYGQITVRMHTRQTLAIYDRFGRLMYGQEDVPKDVLEYVVFEKQLTNPYGSWRMHTKIVPPWAPPKQPILKTVMIPGPQLKPEEEYEEAQGEAQKPQLA
The following text describes a protein:
Function:
Uptake of acetate and succinate. Transport is energetically dependent on the protonmotive force.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIFYGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVYLGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLICGASAIYLAMGEVLNEQFGRTVLPIGESH