lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for programmed cell death (PCD) associated with hypersensitive response (HR). Involved both in the induction of EDS1/PAD4 mediated HR and in accelerated cell death in the acd11 mutant. Not required for HR induction elicited through pathways exclusively dependent on CC-NB-LRR resistance proteins.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm, cytosol.
Sequence:
MDILKSYHLLAAAYSAPAWASFMAGAFLVLTLSLSLFLVFDHLSTYKNPEEQKFLIGVILMVPCYSIESFASLVKPSISVDCGILRDCYESFAMYCFGRYLVACIGGEERTIEFMERQGRKSFKTPLLDHKDEKGIIKHPFPMNLFLKPWRLSPWFYQVVKFGIVQYMIIKSLTALTALILEAFGVYCEGEFKWGCGYPYLAVVLNFSQSWALYCLVQFYGATKDELAHIQPLAKFLTFKSIVFLTWWQGVAIALLSSLGLFKSSIAQSLQLKTSVQDFIICIEMGIASVVHLYVFPAKPYGLMGDRFTGSVSVLGDYASVDCPIDPDEIRDSERPTKVRLPHPDVDIRSGMTIKESMRDVFVGGGEYIVKDVRFTVTQAVEPMEKSITKFNEKLHKISQNIKKHDKEKRRVKDDSCMSSSPSRRVIRGIDDPLLNGSFSDSGVTRTKKHRRKSGYTSAESGGESSSDQAYGGFEVRGRRWITKD
The following text describes a protein:
Function:
Is a substrate receptor for the CUL4-DDB1 E3 ubiquitin-protein ligase complex (CRL4). The complex CRL4-DCAF5 is involved in the ubiquitination of a set of methylated non-histone proteins, including SOX2, DNMT1 and E2F1.
Sequence:
MKRRAGLGGSMRSVVGFLSQRGLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRVKPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIRESPHGEPFCLANYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRKPQSSLLRYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWRIPADPEAGGIGRVVNGAFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPGCTGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLSHDYANQSVQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSERSGYTDSESSASLPRSPPPTVDESADNAFHLGPLRVTTTNTVASTPPTPTCEDAASRQQRLSALRRYQDKRLLALSNESDSEENVCEVELDTDLFPRPRSPSPEDESSSSSSSSSSEDEEELNERRASTWQRNAMRRRQKTTREDKPSAPIKPTNTYIGEDNYDYPQIKVDDLSSSPTSSPERSTSTLEIQPSRASPTSDIESVERKIYKAYKWLRYSYISYSNNKDGETSLVTGEADEGRAGTSHKDNPAPSSSKEACLNIAMAQRNQDLPPEGCSKDTFKEETPRTPSNGPGHEHSSHAWAEVPEGTSQDTGNSGSVEHPFETKKLNGKALSSRAEEPPSPPVPKASGSTLNSGSGNCPRTQSDDSEERSLETICANHNNGRLHPRPPHPHNNGQNLGELEVVAYSSPGHSDTDRDNSSLTGTLLHKDCCGSEMACETPNAGTREDPTDTPATDSSRAVHGHSGLKRQRIELEDTDSENSSSEKKLKT
The following text describes a protein:
Function:
Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras (By similarity). Inhibits Ras-independent, but not Ras-dependent, activation of RAF1 (By similarity). Represses integrin-mediated cell spreading via inhibition of TESK1-mediated phosphorylation of cofilin (By similarity).
Subcellular Localization:
Cytoplasm. Cell projection, ruffle membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor). Colocalizes with TESK1 in vesicular spots in the cytoplasm (By similarity).
Domain:
The Cys-rich domain is responsible for the localization of the protein to the membrane ruffles.
Sequence:
MEPPVPQSSVPVNPSSVMVQPLLDSRAPHSRLQHPLTILPIDQMKTSHVENDYIDNPSLAPATGPKRPRGGPPELAPTPARCDQDITHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPVAEQASPRAVRLQPKVVHCKPLDLKGPTAPPELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSGSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDTKTSRSDKPF
The following text describes a protein:
Function:
Involved in cell division inhibition; this function can be repressed by DicA and DicC proteins as well as antitoxin CbeA (yeeU).
Sequence:
MKTLLPNVNTSEGCFEIGVTISNPVFTEDAINKRKQERELLNKICIVSMLARLRLMPKGCAQ
The following text describes a protein:
Function:
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys-9' trimethylation is coordinated with DNA methylation. Plays a role in promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) or other tumor-related genes. Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs). Associates at promoter regions of tumor suppressor genes (TSGs) leading to their gene silencing (By similarity).
Subcellular Localization:
Nucleus. Chromosome. Note=Associated with non-pericentromeric regions of chromatin. Excluded from nucleoli and islands of condensed chromatin (By similarity).
Domain:
In the pre-SET domain, Cys residues bind 3 zinc ions that are arranged in a triangular cluster; some of these Cys residues contribute to the binding of two zinc ions within the cluster.
Sequence:
MSREKDDENLLRMTKDDLQRWIQAEVERNPHLMQRREQLAQVEEWVKQKERDSTCTRLLYSNACESVLECESVMKGLYALLGLDYRDEDSEEEGGGGQPHDVIQIADDEAERRGNVICNGEDDDNDDLVVIDLGATKETLEPMLEKVTVAIQKSSKLVQDLVQMVSKTSMGATSPLSTSSSDINRPSSSSTPEIVRPESVTPKLEITNSITIVKTESLSSVPKISSLFNSSEQCKSIADHDSYFKPTIKTEPEWTPLTPWEDSESSPFEKLIKTESQSTDVTPSVMTPNKQPELLSFQSTTKIKPEPQSTQANTELSSPPSNSKLLENHNSLSIAAIKNESQLKASVSEVDLLESDSEQSDNAATKTRFKPSEVTASSKLKSSGDHNSASASLNRTDPKVRPVTPSGTPPPSKSPPAVDNTASVETNQTDSELPTETPVEESTLPSNPKEAVIMSDAESTDKTEKPQTRKKSSKPSVTTTSPESRLTSSKSPPVTKTSSTQKETARAQSPSDSIDESADMEDSPDEPSNSPTESPTKTPDKTTRNDAPAKPSKAKKSSKHSSSESSKTLKEIKLKVGAAVLGKKRHNHWSRGTVQEVETEDDGNTYKVEFKKGKTIVLSANHVAAYKPPSLKDLYIGCRVVASAKSENGKSLYNAGVMVELPERKNRMRFLVFFDDGLATYLALPDLYFVCKQTKKVWREIKDESSRKQVKDYLQVYPNPIAVVLRLGQETKAVRNGQFEDCTVLQLDGSLVQICYKNDKQKEWIYKGSDKLEHILTIKNRHKQHSHKKHHSPEGKTQSSQPKTLHSSKSASTSTSSANVSPVSSDSVSPARVTRQSDKTKTSISPQKIMSPAFQPKVVLQKISLPSSISPAARVSNSNTNSSLISAKRPAPDEEEDEYFSEDEVEVLEQEQNKSVYLHQRCCPACLEEVRPHQVDIHHGKNPLLIPLLFKFRRMTARRRIDGKLFFHIFYRSPCGRSLCDMQEVQDYLFETRCDFLFLEMFCMDPFVLVNRARPPSTTTGQPHLYLPDISEGKEVMPVPCVNEVDNTLAPNVTYTKDRVPARGVFINTSSDFMVGCDCTDGCRDRSKCACHKLTIEATSLCTGGPVDVSAGYTHKRLPTSLPTGVYECNPLCRCDPRMCSNRLVQHGMQLRLELFMTQHKGWGIRCKDDVPKGTFVCVFTGKIVNEDKMNEDDTMSGNEYLANLDFIEGVEKLKEGYESEAYCSDTEVESSKKTITMKTGPLLKNSLYKEDSSSGEEPMEVDTAKDKVKVHDKPLGERKLPNKPHETPKDTQKKISELRKNDGQESSGPKRCFAIKSFQRRVKPLESTEAQKEKTKTPKNTRGLFNDEDACYIIDARQEGNLGRYINHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIKAGTELTWDYNYEVGSVEGKVLLCCCGSLRCTGRLL
The following text describes a protein:
Function:
Essential protein during embryogenesis. Involved both in gene transcription regulation and in processing events critical for proper rRNA biogenesis and nucleolar organization during reproduction; contributes to pre-rRNA processing at the 5' external transcribed spacer. Binds RNA (By similarity).
Miscellaneous:
MISCELLANEOUS: 'Thallo' is the Greek goddess of buds and shoots.
Subcellular Localization:
Nucleus. Nucleus, nucleolus.
Sequence:
MGKKGGTLKRSSKSTKTRKDIVEDQYDDEIDAFHKQRDIVPLDVNDDTDESDEDDVQPVFDLQGVDDESEEDEDTEDEEEAENGLTAKMIRQKKYLRAKFGDGDDEMADDDKDKEEDKRSTWGGRSGLYHSGDNVDFDILSSDDEDIKAEEEEVIRLRAEQLGSITAADAGLDDDSEEDSDRELTMEEISDKGKQATKSITDKKEKGDKDTHVEEIKKDINSLSKEEQMDVVYSSAPEIVGLLSELNDAVEELESKINPVMNKLKEGEISLNGLARYLEVKQLLLLTYCQSITFYLLLKSEGQPIRDHPVLARLVEIKSLLDKIKELDEELPPGFEESLARSIANGAVQKVVKEDQLTSPVSDSVDRITQDTAKPMKIDNAREEKKKKGEKRKHQNDLVDVQSEEMLKLRAALEGKLRTNGVLGSTVSKSDKAQKRQKLANRKLETFDDYVDDADNSTHNVTADKLTKLVSTKRKPKTISGDDDLPQRDDIGERRRKFELRVLAGAGVKSSEGDGRNKNGAFASDDEDDNDGDNNDMVDNDGESEDEFYKQVKQKQQAKRAAKAEIYSRKPHLMPSSPEHVDGKRHISNQMVSNRGLTRQRNRDLKNPRKKYRKNYEKKVTRRKGQVRDIRKQTGPYAGEARGINPNTSRSIRM
The following text describes a protein:
Function:
Involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond. Involved in cell wall biosynthesis (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MQEQIEGAVDEELLKQSVLNNDEDDRRLTKLRIERFRTTHTLYIFLYSALAALQFIAIAFFTRGFLLSRKVLDDVANRDESTAPAKFDRLVLLVVDALRFDFVIPVDVAAEGYNSHYHNHLRALYERWDESILLKFLADPPTTTLQRLKGLTTGSLPTFIDAGSNFNGDVIDEDNIIKQMCLNNKTIYFAGDDTWDALFHPYLSNVSMPYESLNVWDLDTVDNGVISFFEDHLLNNPTEKKEWDVLVGHMLGIDHVGHKYGPSHFSMAEKQSQVDGFIRQIIDAVDEDTLLVVMGDHGMDHTGNHGGDSPAELESTLWLYTKRPGTWRRQAPAAYNTTELGRYYRAVNQIDLVPSLSLLLGLPIPFNNLGWPIEELAHDDDEWRLFTRQTLMQLETYRNTSNSITDSSKLKILEELKINANSNSSDAGNYQAILLEMYKDLWARFDYYSIGTGIILLIISLAMLITITRLIPSIVVGQMLSELVPTIIVMPLVSNVCFLGVFYVLRQPAFLQNWLWASLLATAVGIIIGFYVPIFDRYNLTWLVLRFGEELSDYWSRVAAFLITLHALIFTSNSFTIWEDKIVSFSLTTLGMLTLYEFVFLPKRHSTSAILAAALGEKEGTVSGISSGQANSDSLPLGRFARIVGGYHSIVLIVCTRLASLITICREEQGAYCTPTFTLTNNYSFSVMLGCLFLVFATPACIKGYYNVSSSYQAAAPIWIGMLMKSILFVNFIYWELKTFENTSDTHGLNLTIFNLTISRIVVGVSLVAANIGWMMGPLCIKLNVHNNDRRSQQATILGYANAYGAQYFLLVINFFMCILLFNKPLAQLSLFLMCNQLLSILEIFDLLKLKENLIGPVALGLLSYQQFFSTGHQATIPAVQWDMGFILTERITFPFTHLGIVLNTFGPHILCGISVALLTLWKQPPGILRANTLLARVVSNCGMLLIYQTVLCLSTFIWVTNFRRHLMVWKIFCPRFMFAALSLIVTQLVLTFITIAFASGRLIKQIDRMFWK
The following text describes a protein:
Function:
Binds to 23S rRNA.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MEELRSLLDLNFEDVVEGEAAEVREGDLVQFNYVCRRANDYFVHRCVVEFPDAIALLFDACTGDACCTAPDFDTVDQFNGESRPVTLALGGEEVTSFTPEFVYPPEMIPLWCAAPAKKGDAKIQALKVAKAVKSGVGKKKTKKIQSAMKKIEDNNTLVFIVDLKADKKKIKAAAKMYDIQAKKVNTLIKPDGKKKAYVKPMPDYDALDVARCLLDSVEVEFSYDADISLVSVDLLMPD
The following text describes a protein:
Function:
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Sequence:
MKDVKALKLMTLNDVLSQINGDMTLGIGTGSTMELLLPQMAQLIKERGYNITGVCTSNKIAFLAKELGIKICEINDVDHIDLAIDGADEVDPSLNIIKGGGGALFREKVIDEMASRFVVVVDETKIVQYLGETFKLPVEVDKFNWYHILRKIESYADIKVERRVNEDVAFITDNGNYILDCKLPKGIDPYKFHEYLIHLTGVFETGYFLDMADQVIVGTQEGVKILEK
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MKNNHKRRFQDVDHLIQLRKKAIPNKGEYLYDYKLQDALKKRDTYSKEEFKQKFKIDFEDLPISTNTLRALKQRKFIKMTEIQRCVIPHALAERDILGASKTGSGKTLSYLLPLIENLYVNKWTPLDGLGALIILPTRELAMQVFEVFKSLNTYHILSMALLIGGKNYQYERDRITGMNVIICTPGRLLQHFEESPGFDANNLKVLVLDEADMMLELGFWGPLKAIMNYLPKEKQTMLFSATLNQTIHQLCKISLQNPESIFLHEKLATDSNEQTDNVMSTPNKLQQFYIVTPIEEKIDVLFSFIKSHNKQKIVIFVSTCKQVRYLFEVFRKLKLGMLLYELHGRQKQDKRTAIFFTFSEKKAAALFTTNIASRGLDFPKVDWVIQFDCPDDPSTYVHRVGRTARYIAGGFSMLFLLPSEVKFIDKVKQKGVEIKQKFLNSNKQLTIKQTIQSLVSENIELKYLAQRAFISYVRSVDINADKEIFKLKEIKTDLLAESMGLVQVPILTVQQPDESDQEDKPEKKSKLQKLKEKIEIKKQMAIDQNKPIETKKLKQISRESGFDKFEGMKAKTFDFEGEFLKRKPQQEIEEEEEELEQPKFVTSKRQMKKVKADGIFGGRNKVFFDDEGNQITAEEKRRQEILEGQQEVLQKDEDRTLKYGQKLIEHAEDDKANEKDRIKQKRLKKKIRMQEVQEEY
The following text describes a protein:
Function:
Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity).
Miscellaneous:
MISCELLANEOUS: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.
Subcellular Localization:
Cytoplasm.
Sequence:
MDFLDFEKVFSFYSKATKKGFSPFFVPALEKAEEPAGNFFLDRKGNLFSIREDFTKTVLNHRKRYSPDSQIKVWYADFVYRYSGSDLVAEYQLGLEKVPRNSLDDSLEVLEIIVESASEFFEGPVIVEIGHTGVYEDLLKEIPKDLHEKVLNLIDTKNLAEIEFLSHMKKIDLSRVEKIIEDSIYRRSPEHLKTMDLPLSVREDLLSASSFLQEKFPTVSVEIDLTLARTIEEYCGLIFTIYDTSSSRLVAAGGEYTVNGEKGVGGSIFLEGKTC
The following text describes a protein:
Function:
Phosphatidylinositol 3-kinase that functions as a part of the autophagy-specific VPS34 PI3-kinase complex I that plays a role in autophagosome assembly. This complex is essential to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre-autophagosomal structure. Also functions as part of the VPS34 PI3-kinase complex II (By similarity).
Sequence:
MDRLVFSYCPSSKVTARFLVKFCFIEYQDSQEPCICTIQLFSGNESGSLMQKCFVSKIPNKSLLPTELSKISTHEWLDFGVTVSELSLNAKFVVSAWKPSFNDEEVYEFVGCTTYRLFDENNLLRQGLQKIPLQTSKEIKKYSPTSLELEQVKEINRLDGLLLKLQLGDVPSVNWLDDISFGKIKDFRSKHMSLVTIPILYLDFLQFSFPVVFQRSYYPKSENRVYYSSFDLELNLDSPAELKHRRLVRSQRNGPLDKDLKPNSKIRKELESILSYPPSEELSLEEKDLIWKFRFYLTRNKKAMTKFLKSVVWTDSSEVNQALSLLDSWTEIDIDDALELLSPSFVHPKVRAYAVSRLETASNEELLLYLLQLVQALRYDNPISSDERFQPSPLALFLVNRAISSPSIGNDLYWYLVVEIEDEPVSKLFSSVMFLFQKELSKSVEGRLIRETLSAQAKFVEKLLRISKSVQSFRGTRLKKIEYLKVLLEDHKYHLLDFHALPLPLDPSVNIVGIIPDACTVFKSTMQPLRLLFKCQDGSKYPIIFKNGDDLRQDQLVIQILTLMDKLLKKEKLDLHLKPYRILATGPTHGAVQFVPSKTLATILAEYHGSVLAYLRENNPDDGLNSANYGIDPVAMDNYVRSCAGYCVITYLLGVGDRHLDNLLITKDGHFFHADFGYILGRDPKLFSPAMKLSKEMVEGMGGYNSPFYQQFKSYCYTTFTALRKSSNLILNLFSLMVDANIPDIKFDKEKVVYKVKERFCLQMSESDAIKYFEQLINDSVSALFPQIIDRMHNLAQYMRS
The following text describes a protein:
Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Subcellular Localization:
Plastid.
Sequence:
MAISASATVSTSSKLAYPHPSPSSTSSTFSFKPTNNLTPKTLLFSSFISPFLTTTCSTSTSSPTSTIRRRSFTVRAARGKFERKKPHVNIGTIGHVDHGKTTLTAALTMALAAMGNSAPKKYDEIDAAPEERARGITINTATVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSGADGPMPQTKEHILLAKQVGVPNMVVFLNKQDQVDDEELLQLVELEVRELLSSYEFPGDDIPIISGSALLALEALMANPSISRGENQWVDKIYELMDSVDSYIPIPQRQTDLPFLLAVEDVFSITGREKLGNTTVTGVEMFQKILDEAMAGDNVGLLLRGVQKVDIQRGMVLSKPGTITPHTKFSAIVYVLKKEEGGRHSPFFAGYRPQFYMRTTDVTGKVTAIMNDKDEESKMVMPGDRVKMVVELIVPVACEQGMRFAIREGGKTVGAGVIQSIIE
The following text describes a protein:
Function:
Has both general peroxidase activity and dye-decolorizing activity. Can catalyze the oxidation of both protoporphyrinogen IX and coproporphyrinogen III to their corresponding porphyrins. Also efficiently decolorizes the dyes alizarin red and Cibacron blue F3GA.
Subcellular Localization:
Cytoplasm.
Sequence:
MSQVQSGILPEHCRAAIWIEANVKGEVDALRAASKTFADKLATFEAKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFPGYGKGLAPTTQFDVLIHILSLRHDVNFSVAQAAMEAFGDCIEVKEEIHGFRWVEERDLSGFVDGTENPAGEETRREVAVIKDGVDAGGSYVFVQRWEHNLKQLNRMSVHDQEMVIGRTKEANEEIDGDERPETSHLTRVDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAMLRFTKPVTGGYYFAPSLDKLMAL
The following text describes a protein:
Function:
May have a molecular chaperone role in the processing of secreted materials. Required for shoot apical meristem (SAM), root apical meristem (RAM) and floral meristem (FM) formation, probably by regulating the folding of CLAVATA proteins (CLVs). Also involved in pollen tube elongation. Involved in resistance to tunicamycin- or high calcium-induced ER stresses. Possesses ATPase activity.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MRKRTLVSVLFLFSLLFLLPDQGRKLHANAEESSDDVTDPPKVEEKIGGHGGLSTDSDVVHRESESMSKKTLRSNAEKFEFQAEVSRLMDIIINSLYSNKDIFLRELISNASDALDKIRFLALTDKDVLGEGDTAKLEIQIKLDKAKKILSIRDRGIGMTKEDLIKNLGTIAKSGTSAFVEKMQSSGDLNLIGQFGVGFYSAYLVADYIEVISKHNDDSQYVWESKANGKFAVSEDTWNEPLGRGTEIRLHLRDEAGEYLEESKLKELVKRYSEFINFPISLWASKEVETEVPVEEDESADEETETTSTEEEKEEDAEEEDGEKKQKTKKVKETVYEWELLNDVKAIWLRSPKEVTEEEYTKFYHSLSKDFTDEKPMAWSHFNAEGDVEFKAVLYVPPKAPHDLYESYYNSNKANLKLYVRRVFISDEFDELLPKYLSFLKGLVDSDTLPLNVSREMLQQHSSLKTIKKKLIRKALDMIRKLAEEDPDEIHDDEKKDVEKSGENDEKKGQYTKFWNEFGKSVKLGIIEDAANRNRLAKLLRFETTKSDGKLTSLDQYIKRMKKSQKDIFYITGSSKEQLEKSPFLERLIKKGYEVIFFTDPVDEYLMQYLMDYEDKKFQNVSKEGLKVGKDSKDKELKEAFKELTKWWKGNLASENVDDVKISNRLADTPCVVVTSKFGWSANMERIMQSQTLSDANKQAYMRGKRVLEINPRHPIIKELKDRIASDPEDESVKETAQLMYQTALIESGFILTDPKDFAARIYNSVKSGLNISPDAVADEEIEAAEEPETSEATETKSDDLAGGLNIEAEPVEQQEENTKDEL
The following text describes a protein:
Function:
Probable transcription factor involved in the regulation of flower development. Required for the promotion of flowering under short day (SD) conditions and the suppression of flowering under long day (LD) conditions. Positively regulates the floral activator HEADING DATE 3a (HD3A) under SD and negatively under LD conditions.
Miscellaneous:
MISCELLANEOUS: The GIGANTEA-CONSTANS-FLOWER LOCUS T (GI-CO-FT) pathway to control photoperiodic flowering under LD is conserved between Arabidopsis and rice, but the regulation of the downstream gene by the upstream regulatory gene is reversed in the two species. In Arabidopsis, GI acts as an activator of CO, which in turn activates the floral activator FT under LD conditions. In rice, GI activates HD1/CO in a similar manner to that in Arabidopsis. However, under LD conditions, HD1 suppresses HD3A/FT expression, causing the suppression of flowering.
Subcellular Localization:
Nucleus.
Sequence:
MNYNFGGNVFDQEVGVGGEGGGGGEGSGCPWARPCDGCRAAPSVVYCRADAAYLCASCDARVHAANRVASRHERVRVCEACERAPAALACRADAAALCVACDVQVHSANPLPAITIPATSVLAEAVVATATVLGDKDEEVDSWLLLSKDSDNNNNNNNNNDNDNNDNNNSNSSNNGMYFGEVDEYFDLVGYNSYYDNRIENNQDRQYGMHEQQEQQQQQQEMQKEFAEKEGSECVVPSQITMLSEQQHSGYGVVGADQAASMTAGVSAYTDSISNSISFSSMEAGIVPDSTVIDMPNSRILTPAGAINLFSGPSLQMSLHFSSMDREARVLRYREKKKARKFEKTIRYETRKAYAEARPRIKGRFAKRSDVQIEVDQMFSTAALSDGSYGTVPWF
The following text describes a protein:
Function:
Putative Notch ligand involved in the mediation of Notch signaling.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Secreted.
Sequence:
MAMHFKSISFWHSKETCEFYVGTDADSYLIERAHYSGVILPRSEWQTMSFAGHTAILKYKIRVQCDLHHFNVTCTKFCRPRNDTFGHYTCDSNGDKVCLNGWIGTNCETDKSSNDMMMREGKRLEMKMFIVKLQKGTLKTTNVKILKIEDEHFTSGCYRLILPPPSFTLIILFLVFFRGINNEQTLNGWEGELCGQCSKHPGCKHGTCRTSPWECHCEPNWGGPLCDKDLNYCGRHSPCLNGGLCINKAPDDYQCQCLNAFEGRNCEIARYQACSKRPCQNGGSCVLKGVQLLCQCTEGWAGEMCQINVDECSSNPCQHGGTCIDGVAGYQCICPSQWQGGRCEHDADECIKFPCLNARSCQNIVGDYLCHCIEGWTGRNCDISLYGCKKGCHNNGKCMKAVVGYSCVCKEGFTGSQCESAISKCSSQPCQNSGTCRDGPAGAYRCMCPEGYSGPNCELQRDPCEPNPCQNYSPCHRQGSSYLCECSDCYTGPTCSVKKENCGHSNHKDICAYPTSSSSCGKHGNCIRSSAGVQKCVCDAGFTGLHCHENINDCANNPCMNMGTCVDGVNNFQCICSDGWEGHLCNIDQNDCSPNPCRNGGTCIDMLAGFKCLCREGWKGRTCSSKVSHCDSQTCLMGGTCVELHDTFKCLCPNNLHGDICQSVINTSCRTNPCQNGATCVNTGDTFTCLCVEGFTGTSCEINVNDCNPYPCYNNGQCVDGVNWYQCRCLDGFTGHDCKTVVGNLSLASKSCLFQSSMYAHNFRWTSDCNSCVCYDGLVQCTNIWCGPSSCHLNHPTSPHSNSSSQLACGPDEICVVQSESRCFTPPCSLIGECRHMINIGQSKIISSSDENIINMKCRPNLLVTSRACVRMMLTFDRKHAPQGVTVDDVCRIIRNISALNGMTTGETLVILCDVQLDDADTIESLLEPHNLSEDDVMKYSHQMANDIEEVIKRKESNWTLFSSVVRVRLEDFTTNEGNSLDLPVYLIPLVTAIIVLAGIIAIILLVFWHRKFVRRCRQKKEQTDALMKLDAPPNNDCQLNKLNNLNNNNNNNNNNNINNNNNNNNNNNNNNSYKSCSNSQRELQPLNRHHNQIHSNADNDDAIRNNKVNWDKALKSKKNVDKKQNNLPSAGPCDMKMETYDDSPAQRPHKIKQINVKLNKDNVIKNINTSSSSSSSKSSSSSSMHENNTAALEFKPSNNKKFNCERDSYAEDCSEDTKLKNRILLSDPNKDINTDVKFSPNYDVIL
The following text describes a protein:
Function:
Involved in mitotic spindle assembly checkpoint signaling, a process that delays anaphase until chromosomes are bioriented on the spindle, and in the repair of incorrect mitotic kinetochore-spindle microtubule attachments. Phosphorylates spc7/knl1 on MELT motifs; phosphorylation is required for recruitment of the BUB1-BUB3 complex to kinetochores.
Sequence:
MSKRNPPVTNIADLVSDSSLDEDSLSFLEELQDPELYFKNDTFSSKSSHSDGTVTGDTLRRQSSGATALERLVSHPRTKNFDLQGNGGQNSALKEVNTPAYQSMHHFEHLITPLPSTNASHSEVSLSAGVNDLNSNSEHDLLPKSVNKTPGSLSISRRRRIGRIGLGPPKRAEYTLTDPSKTSDTKNSTEADEDIEMKSREVSPASNSVAATTLKPLQLHNTPLQTSQEHPKPSFHPSQFESSFSPRVQFDHDVERRASELHSRPVTVFQEPQRSASQPYESHALSPKVAPLFDNSQATPIPKRQQDVVTVANLQFIKLGVVGKGGSSMVYRIFSPDNSRLYALKEVNFINADQTTIQGYKNEIALLRKLSGNDRIIKLYAAEVNDTLGQLNMVMECGETDLANLLMKNMKKPINLNFIRMYWEQMLEAVQVVHDQNIVHSDLKPANFLLVEGNLKLIDFGIAKAIGNDTTNIHRDSHIGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQMVYGRAPFAHLKMIQAIAAIPNEQYHIHFPEVALPANAVQEKEGSLPGVTVGPDLMDVMKRCLERDQRKRLTIPELLVHPFLNPLPSYLTPLAKKPLPVSGHTNNAHPLRLSTEISASQLSMIIERSVELSKHKRLNKELIDSMAYDCVSNLRKMPE
The following text describes a protein:
Function:
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA (By similarity).
Sequence:
MVDNMISKAYYTTEIPEDRFEALSCIKDSQKPLKIILLGGVDSGKTTLATFLANELLNLGFKVAIVDSDVGQKSILPPATISLAFPETNFNNLYEIKPYKSYFVGSTAPIQFFGEMITGTKLLCDYAEDKADIIIVDTTGLISGSGADLKRMKIEMIKPDIIIALEKRNELKSILKPFENKIRVFYLKVYENAKSFSREERKEIRAEKWKEYFKNSKIYNIGFNDVVIGGTKVFQGEKILEDEKYLLESLFKWKILYGSKCDGRYTIVKRDLVNMPRQIDKNILYYIEPERFNNLIVGLIDEDSFCIGLGILKTIDFENETLEILTPISEEDIKNIREIRFGRIRVDENGEELGLLDRDSI
The following text describes a protein:
Function:
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Seems to act as a specific activating factor for CHSY1 in chondroitin polymerization; [Isoform 2]: May facilitate PRKN transport into the mitochondria. In collaboration with PRKN, may enhance cell viability and protect cells from oxidative stress.
Subcellular Localization:
[Isoform 1]: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Cytoplasm, cytosol; [Isoform 3]: Cytoplasm, cytosol. Mitochondrion; [Isoform 2]: Mitochondrion matrix.
Sequence:
MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGSERERPGAGAGTGESWEPRVLPYHPAQPGQATKKAVRTRYISTELGIRQKLLVAVLTSQATLPTLGVAVNRTLGHRLEHVVFLTGARGRRTPSGMAVVALGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLDRLAGHLSLASATHLYLGRPQDFIGGDTTPGRYCHGGFGVLLSRTLLQQLRPHLESCRNDIVSARPDEWLGRCILDATGVGCTGDHEGMHYNYLELSPGEPVQEGDPRFRSALTAHPVRDPVHMYQLHKAFARAELDRTYQEIQELQWEIQNTSRLAADGERASAWPVGIPAPSRPASRFEVLRWDYFTEQYAFSCADGSPRCPLRGADQADVADVLGTALEELNRRYQPALQLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRWPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLASGFLEAFATAALEPGDAAALTLLLLYEPRQAQRAAHSDVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGPPELGRDTGHFDRQAASEACFYNSDYVAARGRLVAASEQEEELLESLDVYELFLRFSNLHVLRAVEPALLQRYRAQPCSARLSEDLYHRCRQSVLEGLGSRTQLAMLLFEQEQGNST
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.
Subcellular Localization:
Nucleus.
Sequence:
MANAMNENRGEPDKTLTFTKQPYIVDVGPRKIKDVKFSMFSGEDVLKLGEVQVSRSQSYVSQEDKRPVDNGVLDAHMGPTNKLGTCETCHGDFHSCPGHFGYLPLVLPVYNVGYMSHVVDILKCICKFCSRILLVETERVNFLKRIRNPNLDHLRKTGIYKQVVKRCTAMASSKKVVICSRCHYVNGTVKKAVGTVGVIHDRSKVQNTTSNEFNDTIYLKGSNTPAKLSPSVGPDKALKLFKKMLDEDCELLYLADRPEKLIISIIPVPPICIRPSVPVAGGAMSNENDITLRLAEIIRANASVREALSGASVHNKSLGVLWDNLQLSVAQYVNSDVRVADSSQQNGKRITGLVQRQKGKQGRIRKNLSGKRVEYTGRTVISPDPNLKITEVGVPIKVAMTLSYPERVSDHNIERLKRAIRNGTYVYPGATHLRKKDGSIMSLRFNARKRLAEELKLGDIVNRHLKDGDVVLFNRQPSLHRMSMMSHRAKIKHWNTFSFNESVCNPYNADFDGDETNIHVPQTEEARTEALMLMGPIELWTGKQLFSVLLRPYADMRVYLNLSVTEKSYTKPSGERVKPYETMCPNDGYIYIRNSELLSGQLGKATLGNGNKDGLYSVLLRDYHSLAAAVCMNRLAKLSARWIGDHGFSIGIDDVQPGDNLNHNTNRIISQGNKKCDNFILDFNKGNLKCQPGCNAAQTLEAQITGVLNKIRDETGKVCMEKLHWRNSPLIMSQCGSKGSPINISQMIACVGQQSVGGQRAPNGFIDRSLPHFPTNSKTPAAKGFVANSFYSGLTATEFFFHTMGGREGLVDTAVKTAETGYMSRRLVKGMEDLFVCYDDTVRDSNAIIIQFTYGSDGRDPSQMEGKSGFPLNFDRLLNKVKATCPAGQHRGMSPTEICEMVDERLSMHDMSTEGGCSEDFRRKLKEFLEKKAATLEFTRRVLNGEESLTLENVAQSICGITSQQLKVFLEVCISRYHNKKIDPGTNVGAIGAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRINEILNATKKIRTPVITAKLTCNDSIPFARLVKGKMERTLLGQVAKSIKLVMGLRSASIIISLDTETIGALHLSCINAKTVKESILKTPRIKLKDKHIRVLDDRRLEVNNPSTYDRNKLLFDLQMLINKLPSVIVMGVGTIERAVINKKKERDKFNLLVEGTGLQAVMGTEGVNGLETTSNHILEVEETLGIEAARRSIIKEIQYTMESHGMSIDIRHMMLLADLMTYKGEVLGVNRFGIQKMKESVLMLASFETTADLLFNAAVKGQVDKIEGVSECIIMGIPIQTGTGTIKLKQRDAQIEKMCKGLELILSE
The following text describes a protein:
Function:
Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MALSRLARTHSKQSGKAISNYLNETGILCEAAPARKYYFYSVSNFADSGNLKHLSGLGKIDLLVFGSRGIRVTPKYQYPSAERILEVSDSEYGNPRLPGLEATRPGEKPRVVVLGTGWAACRFLKGLDTKIYDAVCISPRNHMVFTPLLASTCVGTLEFRSVAEPVSQIQTALATSPNSYFYLASCLGIDTDKHEVYCETVGSVGLAHQPYRFKVAYDKLVIATGADPLTFNIKGVKEHAFFLREVNHAQEIRRKLLLNLMISENPGISDEEKKRLLHCVVIGGGPTGVEFSGELSDFIMKDVRERYSHAKDDIRVTLIEANEILSSFDVGLRQYAIKHLTKSGVRLMRGVVKEVHDKKIVLSDGTDVPYGLLVWSTGVGPSEFVKSLNIPKSTGGRIGVNEWLQVPSVEDVYALGDCAGFLEETGKQVLPALAQVAEREGKYLVGMINRIGQQNGGRAFCSKGITLGEPFVYRHLGSMASVGRYKALVDLRQSKDAKGVSHAGFVSWMIWRSAYLTRVISWRNRFYVAVNWATTFVFGRDNSRIG