lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.
Miscellaneous:
MISCELLANEOUS: Present with 876 molecules/cell in log phase SD medium; MISCELLANEOUS: Involved in mitochondrial-nuclear incompatibility, a major determinant in reproductive isolation between species, through hybrid incompatibility of Ccm1 and its interacting partner 15S rRNA between yeast species.
Subcellular Localization:
Mitochondrion.
Sequence:
MYMARCGPKNNVLCFPFQLSFLFSKRLINKRFKYTLQTEDEKNMMGSLSKNKIITPEDVEFKLAQLREFSNTLKERIHNTKSVNSDGHQSNSIAPISEDSRNVNVTKTSSVPNEEKSKNLSDLIHSSFLEKMDHLVPKVIRERVADDDILAKNLFDRSHSNWAPVIDRLYVSEKRFMDIDSREFSVWLNGTVKYLPFHSILHLDEMLLEQINGDVVKFNTHMYECIFNNLGNLKPTNFNQDGTNDKVILKMKELLERYDKALKITEERINKKEGFPSKVPKMTQAILNNCLKYSTKCSSFHDMDYFITKFRDDYGITPNKQNLTTVIQFYSRKEMTKQAWNTFDTMKFLSTKHFPDICTYNTMLRICEKERNFPKALDLFQEIQDHNIKPTTNTYIMMARVLASSSSNAVVSEGKSDSLRLLGWKYLHELEDKNLYRHKKDDLNLFLAMMALAAFDGDIELSRALYYLFIAKKYKTLCANWKGNILVDQDTIWKSTLMPEMLNYLMLAYARFDPRNLPVLSGYEKGIELRRKFLREFDSSMRLDDTDKLVKFKLPFLPISDLNSEAQVLAESNAIWSFNMENGGTRNTLTSSNEAALEDIKKYRQLLDSFAQEAEDFNEFKFKVMYEVTKMQRESINVNVFNKISLHTYLSIPINLKQQKEFLRRLTFFTFQQHEFEAVIKRLYEGYRNIPSSHTRDQNSISTEAISVSKPETTEDLNLIMHDIWYITCLRHKIMMDTTLYELVMKAAIEFQNEDLAKKVWNDRGKFRTTVPFLKMDQRIRIAKDQKFAHLMVEFFTKQGKYSDAIAIILSSKNRFNWTYSMVRNLHKALEEIEDRNSVEILLDVVNKKSHAKALKWEEQELNM
The following text describes a protein:
Function:
Essential for DNA amplification in the ovary and required for cell proliferation during development.
Subcellular Localization:
Nucleus.
Sequence:
MSTEASVASKWTRPDDFIKLQRLKQKKNKLAARVSNNNNRRPRHQVDETDKSKLLEAKLAQKRKNPFAKSTADAKKLRVDPQLADLEPVVTASSCFVRETPTRPAPAKFVLQKYDPQAFAKLFQHPQINAEDEDDAELAARQKHTAHLPVDWSLKTRARFFCPTELPAIQLKTSQLASGLTSFVRCMDPQRTESTLDISDATRFNQCNYYWQHPHLPWLTLYPRTAKENVGVVVGERERKALAEEWDFSFRGLFQLLRARQCPYFYLCANTFTVLFRAAGVGGRPESHALVTPSTRGMRQALRQEGIEFSMPLKSDNSGNAHDNSFNEESTTTSLGPEAGEDAPPPAQEDEDDDEDWLESLGVDERELRRIQSSHARKQQAAEMREDFSDNSLLLVDGVECQGFFSYLLNAKSAISTVGRLAGVPPTLLSPVAFPKATMQHLVPRSKKVRLDGVDYFSIDIKGLILPTFLPSVAELLSETRQMFSSTLASSINTLAFSKATQKLLETPETPQSDAEGEDAAGQVFGEQNLSECGLLPAVVGSICRTGQHAVGLLERVCYQRDEGYAWS
The following text describes a protein:
Function:
Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair, and which is essential for nucleotide excision repair (NER) and interstrand cross-link (ICL) repair.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MERGLPGERQSMAPLLEYERQQVLELLDSDGLVVCARGLGADRLLYHFLRLHCHPACLVLVLNTQPAEEEYFINQLKIEGVEHLPRRVTNEIASNSRYEVYTQGGIIFATSRILVVDFLTGRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVKKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPAMLAIQTAILDVLNACLKELKYHNPSLEVEDLSLENALGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEKVFGQNSGWLFLDASTSMFVNARARVYRVPDVKLSKKTKTSEKMAGPEEQETKKELVLESNPKWEALTEVLKEIETENKESEALGGPGQVLICASDDRTCCQLRDYLTAGAEAFLLRLYRKTFEKDGKAEEVWVNFRKGDGPKRTMKSDKRPKDAQNKERASTKRGALKRKKKRELTLTQVLGTAEEPPEEGAVEEDLHKQTGSSPEVCGGEIQHESFDLNVSSDAAYGILKEPLTIIHPLLGCSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPGKPLREKASMVVPEEREGRDETNLDLARGTAAMDTPTDTRKAGGQERNGTQPSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPELCVERKSVSDLIGSLHSGRLYSQCLAMSRYYRRPVLLIEFDPSKPFSLAPRGAFVQEMSSSDVSSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSETLPESDRYNPGPQDFVLKMPGVNAKNCRSLMNQVQNIAELATLSLERLTGILGHSGNAKQLHDFLHTAYADLVSKGRVRK
The following text describes a protein:
Function:
Calcium-dependent NADPH oxidase that generates superoxide.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAATEAATDTGSSRRSQDDTTTLVPHSGNLGEPIQKGVKTTRFKDDDEVVEITIVQRDSVAIEDVRVVDDGGSGHSNGFDGLSLVSPSSSRSGKLSSKIRQVKNGLKMKNSSTKAPQTQLGKNMRKRLDRSKSGAAVALKGLQFVTAKVGHDGWAVVEKRFNELQVDGVLLRSRFGKCIGMDGSDEFAVQLFDSLARKRGITKQVLTKDELKDFWEQLSDQGFDNRLQIFFDMVDKNADGRITEEEVKEIITLSASANKLSKLKERADEYTALIMEELDRDSLGYIELEDLKALLLQSPSQVVARSTTHSSKLSKALSMKLASNKDTGPFYHYWQEFMYFLEENWKRIWVMTLWLSICIGLFIWKFIQYRNRAVFHIMGYCVTTAKGAAETLKFNMALVLFPVCRNTITWIRSKTKIGAVVPFNDNINFHKVIAAGVAVGVVLHAGAHLTCDFPLLLHASDAAYEPMKPFFGDKRPPNYWWFVKGTEGWTGVVMVVLMTIAFVLAQPWFRRNKLKDSNPLKKMTGFNAFWFTHHLFVIVYALLIVHGTCLYLSRKWYKKTTWMYLAVPVLLYVSERILRLFRSHDAVRIQKVAVYPGNVLALYMSKPPGFRYRSGQYIFIKCSDVSPYEWHPFSITSAPGDDYLSVHIRTRGDWTSRLRTVFSEACRPPSDGESGLLRADPSKGITETNARFPKLLIDGPYGAPAQDYQEYDVLLLIGLGIGATPLISIVKDVLNHIQLGGSVAGTEPEGSGKAKKRPFMTKRAYFYWVTREEGSFEWFRGVMNEVAEKDKDGVIELHNHCSSVHQEGDVRSALIVMLQELQHAKKGVDILSGTSVKTHFARPNWRSVFKHVAVNHENQRIGVFYCGEPVLVPQLRQLSADFTHKTNTKFEFHKENF
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MSARSTRAKGAAPVQEDSRDAGPAQGKITDVFRQSVQGAAAAQKSQKPALIGTRNATKRTLALAARTAAVTQAASVTPAPPPATTPKRKRRGEDTEQDNDVVLVEHDEEQQQQQDGDEDMEETEAVAAAAKAPNARGRGRRAGAAAPAPPEADKAAGTAAAAQRRSTRAKAAAAAEAPVPAGKASGKGGAAAAAAPAARGKKDGGEAAAAAGGRSTVRHMNSWEVHGEKIHVGDDVYVVEAEDSSQLPGDDEDEPCCVCSRNTDTRRMVECDRCLRGFHFRCLKPALKKLPDGDWLCPDCVAGVPATAHADRHIATSSQAFLFGNKILGLARVTGWMKDRKGEVQVVVRHYKKPEETHMGRQAHHHPREVFLGVGEHVESAACIWSRADVVGPARFAETGGTDTYICEYEYDDRWKRFRRRLASDEDPSAAAASDDDDEWGAAVPSTAAAGGKRRGAGAGAARGGRGRGGADAASSGEEYEAEESDESDRDEEYKPRNTLDGWVIRKPRGAGAARPGLPTRQAAGGRGRGHSYKALLDEEGTGLLLDQGAAAVPERGPVGPLAAARRALALNNTTGGLPCRETEKTALRRFISGAVEEGGDSPGVLYVCGVPGTGKTACCMEVLGGVRQQAQASGVQLVILNALQLPSPQHVYSKLWERMSGQRWGPARALKALEEAFSGGVGAAAGRRHMTLLIVDEIDVLITKDQAVLYNLFEWPMREGSRLAVIGISNTHDLDSRVLPRIASRLSGSKLAFNPYNFEQLQLILNSRLQGVTAVAKGALDFCARKVASTTGDVRRALELLRRATEIAETERAAAAAARGQPPPEDLTGAVGVRQAQAAIKEMYGSLHMTLLRAAGLAPKLVLVALLVEARATNRPEVTVAALHARLTSHLALLTPAAALPLSRVVEAAAALGGQRLVLAEPGWQGPAMRLTLNVPQDDLVSLLRGDPALAAVQSCLA
The following text describes a protein:
Function:
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
Subcellular Localization:
Nucleus.
Domain:
The DBINO region is involved in binding to DNA.
Sequence:
MNGHNNNHDETNRGAMSISSILSGGERRASDASQQPPAPPLQQQSPLQQQPPPALHHPPPPPHLSPHQTHQAPHISPQHSPQNGHTMPGPPMMGHEQHYMQQQHPQHPQHPQQQSPPMLPQHHQHHPHPHHSPQHSPPMLQHQHHSSTSPPMYHKQQPHPQHQHPPPPHPGHMSPQGHPNMSPHPVQHQGPHPGHQGHPGHPGHQGHPAPPDMYAPRIYMSQQQIPQQAPWPIQIPIQGHTSVDGDHSAPESPPADADDPAYADAKTGFLQQVQSRLEAVVQLEELRDKVVIDEYTKTKAYTNAARYAAVKQSAKTSLQKEAIVRVAFVEYEEGGGLAGAHTSASPAASSSSSAAPVSSTSSAPASASSAAGAAAAAAATTSSVSTPKAKKRSKAVSKTSAAASVAAGTSSKEASPAPKPKTKKQLQAEQREKDREIREENAAAKEAAAAAKQLDQAYDSIWKDMARRDAAKVHKTVAATIAVKQSNHRKTAVLASKEARRWQYRTNKSIKDMQGKARRAMREMLSFWKRNEKEERDLRKKAEKEALDQAKKDEEDRESKRQARKLNFLLTQTELYSHFIGRKIKTDEMEDGEAAKDGDEDYEAMEKIAKSGSDVETKRAAELDFDEDDDDKLRQIAMQNAHNQVRRNQQQAQAFDAQSETPTAESGAAADSDDAFQNPTSLGDLQLSQPKLLNCTLKEYQLKGLNWLANLYEQGINGILADEMGLGKTVQSISVMAYLAETHNIWGPYLVIAPASTLHNWQQEISKFVPDFKVLPYWGNGKDRKILRKFWDRKNVKYTRDSPFHVLVTSYQLVVSDAQYFSRVKWQYMILDEAQAIKSSSSSRWKSLLAFQCRNRLLLTGTPIQNSMQELWALLHFIMPSLFDSHDEFSEWFSKDIESHAKEKSQLDQQQLKRLHMILKPFMLRRVKKHVQQELGDKIEIDVYCNLTTRQRVMYKILKSQINLQELLAKAQSGSEENTQSLMNLVMQFRKVCNHPDLFERADVKSAYNFGPSNCGSDKDTWIGSSNRNLISFEVPKLVYREGGFLDVPGEHSKAGSLNKLLKVDLNIWEPSWMGRKRDLVVEEEGGVGRVSRVSQMGVMERVINEVNRDVPSVGALPRYTPAPSPFDVFETLYDSYLHRLEPAYDPRVVAPPVDFVCRDRGFQIEQEEKMGGVDVRRALTPLTLGQELWWLEKAEAEVKGTNVTALTPGSVSLPPNDLFPSRVLDFNGINTLRMPSMSKFISCSGKLAKLDELLAELKAGGHRVLVYFQMTKMMDLAEEYLTFKQYNYCRLDGSSKLSDRRDLVNDWQTKPELFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLVKGTIEERMRDRAKQKEHVQNVVMSGQSQSHEEEVNSKPSRDVALWLLDDDQDEASFVKGKENRGVKRGAEGEEEKKVEEIKKPKTE
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MVGMIDLNTIEEDETTPSCGSLSSPSSSSAASALSASGSGSSTSSVCLELWHACAGPLISLPKRGSVVVYFPQGHLEQLPDLPLAVYDLPSHVFCRVVDVKLHAEAASDEVYAQVSLVPESEEIEQKLREGIFEGDGEEEDGEATVKMTTPHMFCKTLTASDTSTHGGFSVPRRAAEDCFPPLDYTQQRPSQELVAKDLHGSEWKFRHIYRGQPRRHLLTTGWSAFVNKKKLVSGDAVLFLRGEDGELRLGVRRAAQVKCGPTFPAQWNHQLNQISPGDVANAISTRSFFHIYYNPRASSSEFIIPFNKFLKSLDQSFSSGMRFKMRFETEDAAERRYTGIITGVSELDPARWPGSKWKCLLVRWDDMEANRLSRVSPWEVEPSGSGSFSSSNNFTAPGLKRSRSGLPSSKAEFPIPDGIGAPDFRESSRSQEVLQGQEIMSFNALYDGVDGQNQHPSEIRSCFPGYHSSGIAALGSGIRDSIATSNNSYKGIGFNESYRFHKVFQGQEIFPSSPYGRIPNANEARENCSLGFSDGVQRSSSSSRNGWSTLMQGYNTQIRPPAQVSSPSSVLMFQHASNPVPKPSSNFNFNDHVQQTATTRSWFCGPEMQGGDFKLPAHSEPSVKRGGQWSNSPFGLSHEHLQHGVSQPIVAQSAFRGSQDLVSCKSSCRLFGFSLTEDKCLVNKEDNMTLITSPLNPGSSFLPRAGEHFHPKPPAINNAVGSSCTEAILQTRAENYRIY
The following text describes a protein:
Function:
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
Sequence:
MMKRTWRNSFVTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLVVMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIVDINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVENALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAKQRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLINLKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA
The following text describes a protein:
Function:
Putative divalent cation:proton antiporter that exchanges calcium or manganese ions for protons across the Golgi membrane. Mediates the reversible transport of calcium or manganese to the Golgi lumen driven by the proton gradient and possibly the membrane potential generated by V-ATPase. Provides calcium or manganese cofactors to resident Golgi enzymes and contributes to the maintenance of an acidic luminal Golgi pH required for proper functioning of the secretory pathway (By similarity). Promotes Ca(2+) storage within the Golgi lumen of the mammary epithelial cells to be then secreted into milk (By similarity). The transport mechanism and stoichiometry remains to be elucidated (By similarity).
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MAASARGSGRAPTRRLLVLLLLPLLWAPAGVRAGPEEDLSHRNQEPPAPAQQLQPQPAAVQGLEPARAEKGFTPAAPVHTNREDAATQANLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALALMTCLSVLFGYATTVIPRVYTYYVSTALFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPDVETGTSTAIPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTVTIIGGIVFLAFAFSALFISPESGF
The following text describes a protein:
Function:
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Sequence:
MTKKFEFNWQIPVPEPLLTGCVFDRWTEEKDNNELEPNCMFKVDEYGFFIYWKSEGREGDVIELCQVSDIRAGGMPKDMKLYNQLCNKHGENVEEKSLTICSGTDYININYQHVVCPDAATAKLWQQGLRDITHNIKMNNVCVWTNLMKHWMRLGFLVDPRGKVPVKVVARTFASGKTEKLVYQILSDLGLPSGKNDVIEKADFTFEKFYELYHKICPRNDIEELFRSITQGKANAINLDQFINFLNEKQRDPRLNEILYPLYDEKRALEIITTYEQNDEAREAKTLTKDGLIRYLMSDENAPVFLDRLDIYMDMDQPLSHYYINSSHNTYLSGRQFGGKSSVEMYRQTLLAGCRCVELDCWDGKGEDEEPIITHGMAMCTDILFKDVIYALRDTAFVTSDYPVILSFENHCCKSQQYKLAKYCDEILGDLLLKEPIPDYPLEPGAVLPPPSLLKRKILIKNKRLKPEVEKKELELFLQGEFVIEDEVKEDASAVDVTKIAELEAPAAAAAVVPVAAAAASQDGGEEAPPVQYTGSTTNVHPWLSSMVNYAQPVKFQSFDYADKKNVHHNMSSFAETTGMNLLKSQAIEFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQTSDLPMQLNQGKFEYNGNCGYLLKPDFMRRADRSFDPFADAPVDGVIAASCAVQVIAGQFLSDKKVGTYVEVDMYGLPSDTVRKEFRTRMVPANGLNPVYNEEPFLFRKVVLPDLAVLRFGVYDENGKLLGQRILPLDGLQGGYRHISLRTEANFPMSLPMLFCNIELKIYVPDGFEDFMDALSDPRAFMGAAKERSDNMKAMGIEETGKKDKEEAARKEEQRVTEPPLVFDPITVDSLRQEKGFQKTAKKQQKELDAVKKKHAKERAGVQKQQNAAIERLVKGKSKEEIKADPAVRKLIQEQNAQWTEMAERHKKEEWELLKQQLADQQDILRKLMETTQAAQMKQLEAKHEREIKELNSRQAKISVETSKEVANDKTLKTKGEKDRRLREKKQNNIKRFMDEKKTATIKQNREKEKLKVTHDKQLEELANDVQKLIEMYKVDEEEYKLASKYEFFA
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MVTGMKGSNRKWGLFRYLVVPAFLLLFFSFTLSPSPFELPNPQDNGFHANPTVSFVGEASESPVQALIGAIRSATTFSNVSFNDADAKIWRSHNSCAARTELGPRYARKPHTKPLDPNPQWDLVLEEYAALHRTCMRSIGDITEFFRTGTATSSCKFLIMELGGVGLGNKVSLLTSAVLYAVLTQRVILINTWSLISSTMCEPFLGSSWLLDQRFPLPGRHGPESTFLGRLTGLEDPVWKSSRYFEKGVDATKRGKYVPTPSAMKVEFSDPEVTRFYCDTEQAFLAEATWLHFTGCLYFLPKLFAVPAFRPALEALFPDPSLTFTYLLRSLMLPRDNVWQQVKEHDIALFANVDTRVGIQVRFLYGRKVYFERASKRANKHVKQCISENNILPGAVREDERGIGSRTARSGQVIRVFVTSLHTALSEELLRMYDKQETTTGETVMVTQLTHRGKQGFGSDDDVMAMIEILLLSFVDKLLITPLSTFGGLAQAYGAIIPWFVEMKKNSVSCTRAQTPDLCYQMAYAYYDCPHERNIHRGKIQKTVPYIRQCLSVEESAGLQLVPSNLSSKWTSDL
The following text describes a protein:
Function:
Synthesizes nicotianamine, a polyamine which serves as a sensor for the physiological iron status within the plant, and/or might be involved in the transport of iron.
Sequence:
MACQDNYSMSQEAINLSLIYYSNPLHISNVGSSLQHSTILGSLEDNPLDHIDIFHTYPIHVNVSKLEFSLLTKHTTHPPTNIAFVGFGPMPLSSITLAKFHLPNTGFYNFDIDPPANALASHLVSRDPDLSRRLIFHTTDLLNITTEVLHKEAKVKAIEYLEKHMAPEALLMLRSGFEVLTIYHPTTSEVINSVVIARKLGGQASEKQ
The following text describes a protein:
Function:
Possible component of hydrogenase 4.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MENLALTTLLLPFIGALVVSFSPQRRAAEWGVLFAALTTLCMLSLISAFYQADKVAVTLTLVNVGDVALFGLVIDRVSTLILFVVVFLGLLVTIYSTGYLTDKNREHPHNGTNRYYAFLLVFIGAMAGLVLSSTLLGQLLFFEITGGCSWALISYYQSDKAQRSALKALLITHIGSLGLYLAAATLFLQTGTFALSAMSELHGDARYLVYGGILFAAWGKSAQLPMQAWLPDAMEAPTPISAYLHAASMVKVGVYIFARAIIDGGNIPHVIGGVGMVMALVTILYGFLMYLPQQDMKRLLAWSTITQLGWMFFGLSLSIFGSRLALEGSIAYIVNHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLHTLPLPGVGFCVAALAITGVPPFNGFFSKFPLFAAGFALSVEYWILLPAMILLMIESVASFAWFIRWFGRVVPGKPSEAVADAAPLPGSMRLVLIVLIVMSLISSVIAATWLQ
The following text describes a protein:
Function:
Required for several aspects of embryonic development including normal development of the eye.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Predominantly localizes to the nucleus, with some cytoplasmic localization.
Sequence:
MIAAQAKLVYQLNKYYSERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLTEIDARYEGLEVVSPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYIVQITPAFKCTGIWPRSAAQWPLPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFAEAENRLLLGGCRSKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL
The following text describes a protein:
Function:
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MESRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARAYGARSAMPMHQARRLIGVTAVVLPPRGVVYGIASRRVFDTVRGLVPVVEQLSFDEAFAEPPQLAGAVAEDVETFCERLRRRVRDETGLIASVGAGSGKQIAKIASGLAKPDGIRVVRHAEEQALLSGLPVRRLWGIGPVAEEKLHRLGIETIGQLAALSDAEAANILGATIGPALHRLARGIDDRPVVERAEAKQISAESTFAVDLTTMEQLHEAIDSIAEHAHQRLLRDGRGARTITVKLKKSDMSTLTRSATMPYPTTDAGALFTVARRLLPDPLQIGPIRLLGVGFSGLSDIRQESLFADSDLTQETAAAHYVETPGAVVPAAHDATMWRVGDDVAHPELGHGWVQGAGHGVVTVRFETRGSGPGSARTFPVDTGDISNASPLDSLDWPDYIGQLSVEGSAGASAPTVDDVGDR
The following text describes a protein:
Function:
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes.
Subcellular Localization:
Nucleus.
Sequence:
MDSTAGSDASTPTNHTVSSKKRRGRPPKGSYAAYGSSDDDDEEYSGRTRRRNRNTRPRVSAPSSSSTVVPKDLYSHRATLEDDELNFGVVDPEGEKKVNELGYLNGGREYRCRTFTCLGRGNRLYMLSTEPARAMGYRDSYLLFLKHRSLHKIIVDDSEKWDLIERNIIPHSYKGRAVGIVAARSIFREFGARIIVGGRRIVDDYWEGEFRARGFVEGELADPDDKLPPPGMPYNRNQYVAWHGASAVYHPQPSLEAQLPAAARKRKKEPPKDATWLFQHAKATAAYNNDITKYLVQKQDIGYFEPHTNLLHVPLNTQPTKTHWIQAKTGTECPAPKLDILVALNSDVAPQVSIANIPPSVYASCPLHVQEAIRKRQEQEIRSIRLNSMY
The following text describes a protein:
Function:
Plays a central role in chromosome cohesion during mitosis and meiosis divisions by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. Probably act by protecting REC8 and RAD21 from separase degradation during anaphase. Also acts as a spindle checkpoint component required for sensing tension between sister chromatids during mitosis, its degradation when they separate preventing cell cycle arrest and chromosome loss in anaphase, a time when sister chromatids are no longer under tension.
Subcellular Localization:
Chromosome, centromere. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the centromere during S and M phases, dissociates at the onset of anaphase. Colocalizes with kinetochores. Associates with the spindle pole.
Sequence:
MPKRKIAPNKESSRRTVSHDDLTPQIQEFQNLMDLESQKVENIRQSYSRQNSLLAKDNSILKIKVNSLEKKISQLVQENVTLRSKTSISEAIYRERLSNQLQVIENGIIQRFDEIFYMFENVRKNENLPSSSLRTMLKRTSSRSRSCSLSSPTYSKSYTRLSNHENNLSHESSFNKDDGPDLEPKAKKRKSSRRQSMFVSTSLEPEDETGENEPMMENSSVEVPAESHESAQVEETIDALNPEEENSDSVSNFTNSIIEYSIPEENPTEPEHSSSKLEIFNDSTNMLSTVPSNPLPLPLPGPSATLPTTTSDASTVYPSSSSSTNSHPKTKIKHSMKPPRIELKKKVIDEVMPVSNMSSNSEISFTRTRRTRGKAVDYTLPSLRAKMRRPSEKLVDATTVIDIHDLQVSKRNRETSHKRKSLSQDSIPDEPQLREVVVSKDYGTPKGKKTEDEIHEDTAHLMTTSNNNSNNKNEKKLTSNNSPKKSSPLLDITNKSENKKKSTRTKKLFKNAIVNNLSDENSTTRPSKSSKGTSNNNNNYNNFDNNNSNINNVNNKSVSFRLNEDDLAVFDLFGNGKAVKHQPKTYRTKK
The following text describes a protein:
Function:
Serine/threonine protein kinase involved in a signal transduction pathway that plays a role in yeast cell morphogenesis and cell growth. This pathway seems to start by SMP3; then involve the kinase PKC1 that may act on this kinase. BCK1 probably phosphorylates MKK1 and MKK2 which themselves phosphorylate the MPK1 kinase.
Miscellaneous:
MISCELLANEOUS: Present with 112 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MPFLRKIAGTAHTHSRSDSNSSVKFGHQPTSSVASTKSSSKSPRATSRKSIYDDIRSQFPNLTPNSTSSQFYESTPVIEQSFNWTTDDHISAGTLENPTSFTNSSYKNDNGPSSLSDSRKSSGGNSVNSLSFDKLILSWDPTDPDEWTMHRVTSWFKFHDFPESWILFFKKHQLFGHRFIKLLAYDNFAVYEKYLPQTKTASYTRFQQLLKKTMTKNVTNSHIRQKSASKLKSSRSSSESIKSKLKNSKSQEDISNSRSTSESALSPTKSGPSKTDEKNFLHSTSTHQKTKSASSLYRRSFISLRGSSSSNASSAKSPSNIKLSIPARPHSIIESNSTLTKSASPPASPSYPSIFRRHHKSSSSESSLLNSLFGSGIGEEAPTKPNPQGHSLSSENLAKGKSKHYETNVSSPLKQSSLPTSDDKGNLWNKFKRKSQIGVPSPNTVAYVTSQETPSLKSNSSTATLTVQTADVNIPSPSSSPPPIPKTANRSLEVISTEDTPKISSTTASFKETYPDCINPDKTVPVPVNNQKYSVKNFLLDQKFYPLKKTGLNDSENKYILVTKDNVSFVPLNLKSVAKLSSFKESALTKLGINHKNVTFHMTDFDCDIGAAIPDDTLEFLKKSLFLNTSGKIYIKDQMKLQQKPKPAPLTSENNVPLKSVKSKSSMRSGTSSLIASTDDVSIVTSSSDITSFDEHASGSGRRYPQTPSYYYDRVSNTNPTEELNYWNIKEVLSHEENAPKMVFKTSPKLELNLPDKGSKLNIPTPITENESKSSFQVLRKDEGTEIDFNHRRESPYTKPELAPKREAPKPPANTSPQRTLSTSKQNKPIRLVRASTKISRSKRSKPLPPQLLSSPIEASSSSPDSLTSSYTPASTHVLIPQPYKGANDVMRRLKTDQDSTSTSPSLKMKQKVNRSNSTVSTSNSIFYSPSPLLKRGNSKRVVSSTSAADIFEENDITFADAPPMFDSDDSDDDSSSSDDIIWSKKKTAPETNNENKKDEKSDNSSTHSDEIFYDSQTQDKMERKMTFRPSPEVVYQNLEKFFPRANLDKPITEGIASPTSPKSLDSLLSPKNVASSRTEPSTPSRPVPPDSSYEFIQDGLNGKNKPLNQAKTPKRTKTIRTIAHEASLARKNSVKLKRQNTKMWGTRMVEVTENHMVSINKAKNSKGEYKEFAWMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRLAKFIKSNDKLNSSKLRITSQENKTE
The following text describes a protein:
Function:
This protein is not a protease, but it activates plasminogen by complexing with it. As a potential virulence factor, it is thought to prevent the formation of effective fibrin barriers around the site of infection, thereby contributing to the invasiveness of the cells.
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
The following text describes a protein:
Function:
May protect the outer tissues of the pistil from pathogen attack.
Sequence:
MFVLSTAMACLVYIYIYIYDEEKKRELKVRNKMTNLLFFQFLLLTTASSLTHISAQTVPPPPPPPTSAATPPSRAAQEFLDAHNKARSEVGVGPLTWSPMLAKETSLLVRYQRDKQNCSFANLSNGKYGGNQLWASGTVVTPRMAVDSWVAEKKFYNYENNSCTGDDKCGVYTQIVWKKSIELGCAQRTCYEGPATLTVCFYNPPGNVIGEKPY
The following text describes a protein:
Function:
Induces the early late puff 78C which triggers puparium formation and development.
Subcellular Localization:
Nucleus.
Sequence:
MDVYQIELEEQAQIRSKLLVETCVKHSSSEQQQLQVKQEDLIKDFTRDEEEQPSEEEAEEEDNEEDEEEEGEEEEEDEDEEALLPVVNFNANSDFNLHFFDTPEDSSTQGAYSEANSLESEQEEEKQTQQHQQQKQHHRDLEDCLSAIEADPLQLLHCDDFYRTSALAESVAASLSPQQQQQRQHTHQQQQQQQQQQQHPGQQQHQLNCTLSNGGGALYTISSVHQFGPASNHNTSSSSPSSSAAHSSPDSGCSSASSSGSSRSCGSSSASSSSSAVSSTISSGRSSNNSVVNPAATSSSVAHLNKEQQQQPLPTTQLQQQQQHQQQLQHPQQQQSFGLADSSSSNGSSNNNNGVSSKSFVPCKVCGDKASGYHYGVTSCEGCKGFFRRSIQKQIEYRCLRDGKCLVIRLNRNRCQYCRFKKCLSAGMSRDSVRYGRVPKRSRELNGAAASSAAAGAPASLNVDDSTSSTLHPSHLQQQQQQHLLQQQQQQQHQPQLQQHHQLQQQPHVSGVRVKTPSTPQTPQMCSIASSPSELGGCNSANNNNNNNNNSSSGNASGGSGVSVGVVVVGGHQQLVGGSMVGMAGMGTDAHQVGMCHDGLAGTANELTVYDVIMCVSQAHRLNCSYTEELTRELMRRPVTVPQNGIASTVAESLEFQKIWLWQQFSARVTPGVQRIVEFAKRVPGFCDFTQDDQLILIKLGFFEVWLTHVARLINEATLTLDDGAYLTRQQLEILYDSDFVNALLNFANTLNAYGLSDTEIGLFSAMVLLASDRAGLSEPKVIGRARELVAEALRVQILRSRAGSPQALQLMPALEAKIPELRSLGAKHFSHLDWLRMNWTKLRLPPLFAEIFDIPKADDEL
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MYIVKPSWLCHSDDQKKFEVYSVTVSPDNQRVATGGQDGKVRIWSAQSIRDSAKGDNESSDTPSNLSGAPAPGAKQLCSMATHNGAVTVVRFSPDGRYLATGSDDRVVLVWERDSTKVPRKEFGSSGEADTESWIVRKRLAAHDNDIQDLAWAPDSSILVTVGLDSGVIVWSGTTFEKIQRLDAHNSHVKGITFDPANKFFATASDDRTVQIFRYNRASATDVTFSTEATITSPFKQSPLSTYFRRCSWSPDGNHIAAANATNGPVSVVAIINRGTWDSDISLIGHEAPCEVAAFCPRIFARTKEAAEKKDKKSSSEKDKESDVIDVDAEPKVPESVPITVIASAGQDKTLTIWNTSNPRPVVVCHDMALKTITDLAWSQDGMSLFATSLDGSISYVQFEEGELGYVVSMEENESRLTRYGGGKEAAQIPESVEQLVLEEKVEAKEVKDSEKRMEELMGAAGAGSKAIASGATVIPSPASTVAAAAAAPVTTTARATTPLTAATSNPSTPAKPAKQKVTITKDGRKRVAPQLLTTTSSSVQGTLPAATTSSAAVPVASATAETIPVNDFSKPSYALPKGGVSTLVIGSKRRSDDLEDGSNGIQTALKKTRPDDDVPEYIAPVVVSPATTTSQVRLGAPKVRNLLMRSMTVRDAEKPRMANESVSLANGENTSSSSAPHSFNFEVRNGSGNDQTPTKVSVTRNSQVVFVDFVPYYVHLIAGNGCYFWATSAEDGSIVVYSPNGRRMLPPLVTGAPLSFLESQNEYLLAISSVGMLYLWNVVDKKAVFPPVSLAPILDSGSRYEDGGVLRGPHVTQCGVTGSGRVIITLSTGCGYTYDEGLRSWCRLSEPWWATGSQYWSATQLLGDESAKSRWVLAVEERTAEEAQRRAGGRGRYLKQLTRATLNREGYEGMEGVVSIAHLENRIAAAEMLESKHELRTFIIMYARRIAEEGLRSRVDELCRELLGPGKSQDSTWSPTVCGLDKHELLKEVVLKIGKYRESQRVAVVYGQAIGLLEDEVLGVASSSKSAASKGSKDKEDNEEEDGDHDMTDFKDAMSEQ