lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4-hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MRLFLWNAVLTLFVTSLIGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFISAREFTYKHDEL
The following text describes a protein:
Function:
DNA-binding transcriptional activator that interacts with calcineurin-dependent response element (CDRE) promoters. Activates expression of genes required to maintain cell wall integrity during stress. Activates expression of genes required for transepithelial migration through the host blood-brain barrier. Required for adaptation to host temperature during infection.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus. Note=Localizes to the nucleus during calcium signaling, cell wall and heat stress. Localizes to the nucleus following dephosphorylation by CNA1 (calcineurin). Localizes to the nucleus during growth on glucosamine carbon source. Localizes to the cytosol during vegetative growth and osmotic stress.
Sequence:
MADPASPPSFDAIFAQQPVRRSSSTSTSSFANYTYSALQQHQQFNSDAPLVDEPQSLSEQARKQQRDPSKDGNNKRYLDMMSGLADGYGVINGRRQESLRKESLPFNPQEDSTLIATAPKRGERNGLGRNGYSSPIGDIMFGPEQTIPNQPQQPSQQPPWGEGRMSEQSVHYASVQQPQYSSFQSSGPGAGSAGIDYLPRGTTSSMNDSMLSSQISPYLNHDVASEGQPPQQQQQQQQQQQGEWGQEFIGVEQQQQYAQGEGQSNGMEDMLTMGDESPFESELQRVISNTSHPSQYPSRTSSPFPQQSQSNMVPASTVNQTRTESFPASRSPSPFAPQQASQTEASNHVVSTPSMGQPTYPRASSSPRTNPNSPFFNKPQSPPALIIPNSPVLPNIVTQSTSNNHSKGLNQPHTRHASNGAGGLFPPSNPALEHLTGMAGISPIAPNADGPMICIQPSTPISGLKEGRGLFDAALRRAGAARGAQRQGPQGQGESQEDRRQDGFNVPSPQSHPLPRTLSSDQVNQGVEMQGMDFAAQMQSYEQQGWANDTLRIAGPSRPRAKSDSIIPSPTADSFDRQAFLAFIGAGNAQPPPPNVEMQPGYVDVSEQWRNTVSAWKAGLGEGELNSQPTLDPRLLPGRESNEAVYQQLLMQQQTGQMPRLDPDQLHQLTQLEGQRARFSLNTNIAPPKYEPGEISPTSMVFYQSMGLYPHAAPELSGTVSAPWSQTAFGQVPGPGPVGHPATAGPAQQHFLTPTLSHATVRRRSFGGGEHPAMGAGTPGYGMEFSSPFAGKSVGQIRGVNMGHRRAARSEDFGRGGTGWGVGAGGSTAEFLQSITGDDGSLLPPSNRGHAMSHSRHSSTSSIRSASPALSISSQGSSFSHHSPRMDMPDSIYPGHPIIAPATPLQVSGLYEEQQTPARVAKMKVTSVATEVASTSRRTNSGIFKCPVPGCGSTFTRHFNLKGHLRSHNDERPFKCLYEGCPKAIVGFARQHDCKRHMLLHEGLRLFECEGCGKKFARLDALTRHHKSEQGQECAITHPLPTNFDGSPMSESQYKTYKGIKSTPEGSGRRLSSTASGSGSGKRRSKKSETSEED
The following text describes a protein:
Function:
Involved in allosteric regulation of aspartate carbamoyltransferase.
Sequence:
MLTINSIKNGIVIDHIQAGHGIKIFKYLGLEEADYRVALIMNAESSKLGKKDIIKIENIMEIDYKVLGFIDPTITIDVIENETIKEKIKLELPKTIENVIKCKNPRCITSIENYIPNEFYLVDEENGEYRCKYCDEIYSGGDINKL
The following text describes a protein:
Function:
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
Subcellular Localization:
Secreted. Bacterial flagellum.
Sequence:
MRVNDVNLMRYIQQLSLERKAPTPGSFLFNTVSELAVQQKLRGQIEGYKTTLSQIYNGIGLLNTANAGLESISTALQRARELAVQASNATLTDVERSMIQKEYEEIMRGVKRIIQQTTYNEQRVLAGDVRNLVIQTGPNEGQNVTVNIPNLEETLSELFEVDLSTFEGAQRSLETIDQALENISQIRGNVGSWMNRLESSARSVMNSYTELFKTESLFEPSVAELLLESTKEDILRQTALTGILFRMENAGNVLKLLM
The following text describes a protein:
Function:
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
Miscellaneous:
MISCELLANEOUS: Present with 2140 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MGLPKSAYKKLLIDCPTRVINKNCAQRVKDVSPLITNFEKWSDKRKKLYFKDEEEMVGQFHLENFNLKNNLYGRLLASPMRAEKISKLKSCRELLIPLKVVPSTGKDQHADKDKLKLVPTLDYSKSYKSSYVLNSASIVQDNLAAATSWFPISVLQTSTPKSLEVDSSTFITEYNANLHAFIKARLSVIPNVGPSSINRVLLICDKRKTPPIEIQVVSHGKGLPITQSVFNLGYLHEPTLEAIVSKDAVTNGIYLDADNDKDLIKHLYSTLLFHSVN
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC).
Subcellular Localization:
Nucleus, nuclear pore complex.
Sequence:
MFSFSKQNDGNNGFNTNIFPNITVSPFNTVNNTFETTPMEITTTSSSTNSSNNKTSKSSKFCNFKWSPTGDQLLLFKPNIKGSKIKYQVNNTLSSTRKFLNDLYTHFESTQRIANSQVVPDDRLREISHLSKTYLSVILSTISQMVKACKTGSYIDNEDSYINCDPNDKELMDINRERVENILKSGSSNTLVVFCGSSDSIYPLLCSQISNKLKPKCILIARETNQPTQQKQDIINTIKRQTEIRILSKEEYSNRYNYIAENFGNQDSIESADVDDVYFKYIEEIEFLYLASTVWKVASLFYFNISSSMISPNQLLDCIDNERKELMDTYEGIMNKRIETSDPVCFDHMAKLLVCGCIDQVISILGLMSKAPRSASQITSTARKSPINLLVDILTQIPLKKKQSNFNPNETLLQWKKWSTDSKRQLTQYIDSGSSSKNQIDENLLPIIKILLGDQETIRYYCKNSFLQLVISNLLYVEYVTSTSALRSLFTQCYEIIQEPSEIEKIFLSFATKEINYPLKTISKYFPTWLSTHLSDLLYHHPYFMRKSPSEPSELTKVREHLLSEHGQSLASDPALLQVGCNYLKYVENGQFMIDEFISRQPIQYEKNALKMIDNWVTSQETKNSIYKMLSVKDFQRQRYASALSWLILTNDSSRITQLSNYLLENQLNSDFLNDLQSILEKNLQINTNRDNNNNNGSEASTFDISSNNELIFLIKYRELINLWKERSFKEYSSLLCQMFKDKIIPKNFWLRLLLDCIPLFESNKNVYFNYQDTLFLQTCLEEIIQSHLFDQYSQSISNQDIQILRVSLARNLAKSIMVSTSTNNLSLF
The following text describes a protein:
Function:
Regulates floral organ identity and cell proliferation in the inner floral whorls. Probably specifies the identities of lodicule and stamen through positive regulation of MADS16 expression. May contribute to morphogenesis by suppressing OSH1 expression in the lateral organs.
Subcellular Localization:
Nucleus.
Sequence:
MNSSRRQEGSPLDLNNLPDEFGKQTVESSTTTAASSAEASRVTKKKSNGGKDEAGKVYECRFCSLKFCKSQALGGHMNRHRQERETETLNRARQLVFGNDSLAAVGAQLNFRDVNMGGGGAAAPPPTMQMGGGGFRGGGVGGDPCIPLRPVQPRLSPPQPPPYHHYLYTTTAPPSALHPMSYPATYPAPPRHQQPAAVGDYVIGHAVSAGDALVAPPPPPHRASFSCFGAPLAAPPANVQPDNGNCNCSFGCGHSNRNVNAAS
The following text describes a protein:
Function:
Seed-specific transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Seems to be specialized for the developmental expression of heat shock protein (HSP) genes during seed maturation. Activated by ABI3.
Subcellular Localization:
Nucleus.
Domain:
The hydrophobic-rich region (HR-A/B) corresponds to the oligomerization domain.
Sequence:
MTAIPNVVDIESSSSSLCQETATETVTVERGSSDSSSKPDDVVLLIKEEEDDAVNLSLGFWKLHEIGLITPFLRKTFEIVDDKVTDPVVSWSPTRKSFIIWDSYEFSENLLPKYFKHKNFSSFIRQLNSYGFKKVDSDRWEFANEGFQGGKKHLLKNIKRRSKNTKCCNKEASTTTTETEVESLKEEQSPMRLEMLKLKQQQEESQHQMVTVQEKIHGVDTEQQHMLSFFAKLAKDQRFVERLVKKRKMKIQRELEAAEFVKKLKLLQDQETQKNLLDVEREFMAMAATEHNPEPDILVNNQSGNTRCQLNSEDLLVDGGSMDVNGRIEIE
The following text describes a protein:
Function:
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MSCSHNCSNCSLKGNCNQLPNPSNCSHNCDGCPSKGSCSSSTSSQGGCSHNCDSCPSKGKCGGGNNGPDRELEEIIEKLKGIKHKYVILSGKGGVGKSTFATQFSWVLSEDKQVGLCDYDICGPSIPQMFGQIGVNVTSGMTGLQPIYVTENLCTMSIGYLVATETAVVWKGPKKNSLIRQFIHDVDWGELDYLIIDTPPGTSDEHLTIVSILNKCNVDGAIIITTPQDVSLIDVRKEINFCKKIGLPIIGVVENMSGFICPCCHKESTIFPPTHGGAKQMCEEMGVKFLGKIPLDPIIAHSCDIGAPYFLEHPDSEATKNFKRIYKEIITNL
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Sequence:
MVPRRNPEPLRFLPDESRSLPPPKLTDPRLLYVGFLGYCAGLVDNFIHRRPIRSAGLHRHLLYITAFYFVGYYLVKRGDYTYAVRDREMFGYMKLHPEDFSEKEKKTYAEIFEKFHPIR
The following text describes a protein:
Function:
Catalyzes the C6-oxidation step in brassinosteroids biosynthesis. May convert 6-deoxoteasterone (6-deoxoTE) to teasterone (TE), 3-dehydro-6-deoxoteasterone (6-deoxo3DT, 6-deoxo3DHT) to 3-dehydroteasterone (3DT, 3-DHT), and 6-deoxotyphasterol (6-deoxoTY) to typhasterol (TY). Involved in the organization and elongation of the leaf and stem cells. Not able to convert 6-deoxocastasterone (6-deoxoCS) and castasterone (CS) to brassinolide (BL).
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MVLVAIGVVVAAAVVVSSLLLRWNEVRYSRKRGLPPGTMGWPLFGETTEFLKQGPSFMKARRLRYGSVFRTHILGCPTVVCMEAELNRRALASEGRGFVPGYPQSMLDILGRNNIAAVQGPLHRAMRGAMLSLVRPAMIRSSLLPKIDAFMRSHLAAWSSSSSSAVVDIQAKTKEMALLSALRQIAGVSAGPLSDALKAELYTLVLGTISLPINLPGTNYYQGFKARKKLVAMLEQMIAERRSSGQVHDDMLDALLTGVEGTREKLTDEQIIDLIITLIYSGYETMSTTSMMAVKYLSDHPKALEQLRKEHFDIRKGKAPEDAIDWNDFKSMTFTRAVIFETLRLATVVNGLLRKTTQDVEMNGYVIPKGWRIYVYTREINYDPFLYPDPMTFNPWRWLEKNMESHPHFMLFGGGSRMCPGKEVGTVEIATFLHYFVTQYRWEEEGNNTILKFPRVEAPNGLHIRVQDY
The following text describes a protein:
Function:
Guanine nucleotide exchange factor that plays an important role in regulating the growth and virulence, probably by regulating the autophagy pathway. Affects the sensitivity to cell wall disruptors and the cell wall thickness by regulating the expression levels of the cell wall integrity (CWI) pathway genes, thus coordinating the growth and virulence. Positively regulates the autophagy pathway to enhance the expression of CWI pathway genes in the presence of autophagy inducers.
Sequence:
MCPLPHANLSMVTNEVTNFMSSLIAFQTYHLRHSFLSPSNMIPRSSNHKRSLSSGPRSLSPDRTVTKTKSTNDLAATATEKPSLATRSNSAGDIPDSGFSTLRDPRLVNNSEASDTSSTPSHHPDLSSEVAALSVKLIQAINNQTTLDDNLVATRQELEQAQNRIKSLESENEKYRHDIEQAVLIKKADADREISQLKAALAEEKAQRAIVEKSKKTIEQELETLTAALFEEANKMVAAAKLEREAVEKKNEQLRAQVKDTELLLASHQEQLAELKSVMQGMNIAKDDVEVRTTISTVPSSPDGHQQLPGIFPRSLETADPPEQSPHVEEIVPGPSTSFPHLFKSVCRTDIQAFEDFRELFSLSSASKPPSRAASGSYAGLNVMSLANFSSAGFGSASSSPAKSTHSPNGSMSSPQPATSHIPLKETRFYKRVLMEDIEPTLRLDAAPGISWLTRRAVLSSICEGSLVVEPIPPATRKYGFPCSLCGDRRPGSANERTHRFRTSDSDTAQRYPLCVLCLEKVRSSCEFTGYLRLILDGHVRAADAEEEKDAWEETVRLRERMFWSRIGGGVVPTFAQANSFENAGSAPSRHNLGDRIGDDEQDRLDAPLETYETPNHGHDHGVSDSDYDNASVSGYTSASGVSRPFYGSPKSHASEKGKDEYLEHGVSQVTLSATSDDPKSITHVEESLVIRTAKNDDGHDDDQN
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system.
Sequence:
MYNSGKELKRGMVMEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKSEWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE
The following text describes a protein:
Function:
Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 9 (m1A9) in tRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MTLAKVFSQKLRELGISSIYIGHERPSLQSLAIKMLLKNYGLVEERREGMLITQDHGIKLISGKGTETSRYTFRKGGKKVSIHLPEYPKMVIDLGLFEFLNEEEKEKTLLQVDLCLSVIRKFLWDGNLTVVGKADYVLGRANIVQSLSLSDEDNPVILDPYGDVVATDQILRDHNVFVIGGIVDKGRRLDRATERLALSRGYSFPRVKIQLRGSIIGVPDEINKILEIILRVKELDQSLEEAIISLQSKSDKISRLLHDVQLYGMEVLEEEARWLRADDKVIEIVRSRLGKN
The following text describes a protein:
Function:
[Nociceptin]: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development; [Nocistatin]: Blocks nociceptin action in pain transmission by inhibiting nociceptin-induced hyperalgesia and allodynia; [Orphanin FQ2]: Has potent analgesic activity.
Subcellular Localization:
Secreted.
Sequence:
MKILFCDLLLLSLFSSVSSSCQKDCLVCREKLRPTLDSFSLEMCILECEEKAFTSPLWTPCTKVMARGSWQLSPADPDHVAAALDQPRASEMQHLKRMPRVRSLFQRQKRTEPGLEEVGEIEQKQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQRRRTLHQNGNA
The following text describes a protein:
Function:
Probable modulatory (alpha) subunit of inward-rectifying potassium channels. Could mediate potassium uptake from the soil solution by plant roots in association with AKT1.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Domain:
The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids. The pore-forming region H5 is enclosed by the transmembrane segments S5 and S6 in the Shaker-type (1P/6TM) and contains the GYGD signature motif which seems to be involved in potassium selectivity; The KHA domain (rich in hydrophobic and acidic residues) present in the C-terminal part is likely to be important for tetramerization.
Sequence:
MSTTTTEARSPLPLLLRRGRSSTALSASTAEARSPLSILQFRRRSSKDVRNITSVSSSLLPAFGTFIEDDNPSSKPFIVLHFDRRYRLWELFLVILVGYSAWASLFELAFEKAAEGALLTIDLVVDFFFAVDIILTFFVSYLDNTTYLNVTDHKLIAKRYLKSVAFVMDVASTLPIQFIYKTITGDVGRGQAFGFLNLLRLWRLRRVAELFKRLEKDAHFNYFVIRVIKLLCVTIFWIHLAGCILYWIAYHYPRPTDTWIGSQVEDFKERSVWLGYTYSMYWSIVTLTTVGYGDLHAVNSREKTFNMFYMLFNIGLTSYIIGIMTNLVVHGALRTFAMRSAINDILRYTSKNRLPDTMREQMLAHMQLKFKTAELRQEEVLQDLPKAIRSSINQHLFRSIIEEAYLFKGFPEGLLVQLVSQIQAEYFPPKMEIILQNEIPTDFYVIVSGGVDIIASKGVSEQVLAKLGPGSMAGEIGVVFNIPQPFTVRTRRLSQVIRIGHHKFKEMVQSDNDVDAKMIIANFMTYLKGLNDELKKEIPFLRDLLDDADAQVQETVQSEETPQSNDEEIVTVSRHENGQIEERRREGVPKRVIIHGQAPPNQDNKNNGDSNGRLIILPDSIQLLFDLAEKKLGKRGSTIAMADGAHVEQIDALRENDHLYIF
The following text describes a protein:
Function:
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MSSGGRFNFDDGGSYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPSGNTYQGTWAQGKRHGIGVESKGKWVYKGEWTHGFKGRYGIRESTGSNAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRHGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHSNGTALHPDGAGASAAGSPAVSRGGFVLSMHSDAELLKGKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSAASDINSTISLGEGEADLSVIEDDVDATTTETYVGEWKNDKRAGFGVSRRSDGLHYEGEWVGNKRHGYGCTTFPDGTKEEGKYKQNVLVSGKRKNLIPLRASKIREKVDRAVEAAERACDIAKQKAEIALSRTAHARVKAEAAVSAAQKAQEEARLARITAKEFSPSFQHRGNGVECQRPKHQNSSENDIEVISTGTPDSPELYMKGTTPPDLTPDLSPVPSRPSTPPPSPHKPTHRTKNARFLRQSAVDDDRGTGEIQVLLEGRGGGGGGGEYLRPNSWIEDKRPAEGGGGSRGGSRGSSRSNTPSTQEDTRARGSNGHKHASSNHKPRERWADCPTTVSWTTHRSLSESLANSRLLEQDEEKLSNYEMEMKPLKRMDSYMQETHPQKHYGSRGSPSPAEDYHAEARPHGHGLQRLRPKSQAKENFRLACTAEPAVQKLDSLGMGEKLDSRPLWRDLTLSPPQKSLPIALEHDEENLTELKSNSGSSSILVVMVILLNIGVAILFIHFFI
The following text describes a protein:
Function:
Modulator of GLC7 type-1 protein phosphatase.
Miscellaneous:
MISCELLANEOUS: Present with 3440 molecules/cell in log phase SD medium.
Sequence:
MGGILKNPLALSPEQLAQQDPETLEEFRRQVYENTQKNAKLTSHKRNIPGLDNTKEEGEIIGTSSTFLPKDTLSLKHEQDMLAKMTPEERVQWNQRNLAENEITKKQFQDIHIDEPKTPYQGAVDPHGEYYRVDDDEDEDNSDKKPCQVANDDIDDLSLGEPEFEIKENKQPDFETNDENDEDSPEARHKKFEEMRKKHYDVRAIFNKKSREALKDEDEDEDDSTTKEP
The following text describes a protein:
Function:
RNA helicase involved in group II intron splicing. Essential protein required during embryogenesis. Involved in post-transcriptional gene silencing. Modulates the determination of cell fate. Necessary for normal plasmodesmata (PD) development and aperture regulation.
Subcellular Localization:
Plastid, chloroplast. Cytoplasmic granule. Note=Localizes to granule-like structures, probably stress granules (SGs), which number increases upon stress.
Sequence:
MNTLPVVSLTASSSFKFFHFPSLHRSLSHSPNFSFTKSLILNPNHLSFKSTLNSLSPSQSQLYEEEDDEEEEEEDEDDDDEAADEYDNISDEIRNSDDDDDDEETEFSVDLPTESARERVEFRWQRVEKLRSLVRDFGVEMIDIDELISIYDFRIDKFQRLAIEAFLRGSSVVVSAPTSSGKTLIAEAAAVSTVAKGRRLFYTTPLKALSNQKFREFRETFGDDNVGLLTGDSAINKDAQIVIMTTEILRNMLYQSVGMASSGTGLFHVDAIVLDEVHYLSDISRGTVWEEIVIYCPKEVQLICLSATVANPDELAGWIGEIHGKTELVTSTRRPVPLTWYFSTKHSLLPLLDEKGINVNRKLSLNYLQLSASEARFRDDDDGYRKRRSKKRGGDTSYNNLVNVTDYPLSKNEINKIRRSQVPQISDTLWHLQGKNMLPAIWFIFNRRGCDAAVQYVENFQLLDDCEKSEVELALKKFRVLYPDAVRESAEKGLLRGIAAHHAGCLPLWKSFIEELFQRGLVKVVFATETLAAGINMPARTAVISSLSKKAGNERIELGPNELYQMAGRAGRRGIDEKGYTVLVQTAFEGAEECCKLVFAGVKPLVSQFTASYGMVLNLVAGSKVTRKSSGTEAGKVLQAGRSLEEAKKLVEKSFGNYVSSNVTVAAKQELAEIDNKIEILSSEISDEAIDKKSRKLLSARDYKEITVLKEELREEKRKRAEQRRRMELERFLALKPLLKGMEEGNLPFICLEFKDSEGREQSVPAVYLGHIDSFQGSKLQKMMSLDESFALNLIEDELAADEPGKPNVKPSYYVALGSDNSWYLFTEKWVRTVYRTGFPNIALALGDALPREIMKNLLDKADMQWDKLAESELGSLWRLEGSLETWSWSLNVPVLSSLSDEDEVLHMSEEYDNAAQKYKEQRSKISRLKKKMSRSEGFREYKKILENANLTVEKMKRLKARSRRLINRLEQIEPSGWKDFMRISNVIHESRALDINTHLIFPLGETAAAIRGENELWLAMVLRNKALVDLKPPQLAGVCASLVSEGIKVRPWRDNNYIYEPSDTVVDMVNFLEDQRSSLIKLQEKHEVMIPCCLDVQFSGMVEAWASGLSWKEMMMECAMDEGDLARLLRRTIDLLAQIPKLPDIDPVLQRSAAAAADIMDRPPISELAG
The following text describes a protein:
Function:
Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.
Subcellular Localization:
Nucleus.
Sequence:
MEEEVHLKDKIKSGEDDDPDYVSVAVEKSQKQTSLSLQQQDAKDLAVNKIEKIIQDQFALEIRLKEKEVELIDHRISQTKAMLDRLRACVLARYYGTSERLLAGEGLNLRRRTRRTVSGRSGHVFGIGGMMNGNWNGTECNTINKSVDPGLKTQENAISECLTDVIRASERTSSSAFTQSETNKDNSTLHKHEKDCNWLATEAAVGPTAGPITTSQSGGKATLSKAGQNSTTCVTVVGSRFYIKKRIIIGNTSKYIPVERREENDKSTHKWMVYVRGLPDDLPIHSYVQNVWFFLHPSYRPNDIVEIKKPPFQITRRGWGEFPIRVQLHFVDSRNKRVDIIHELKLDKTYTGLQTMGAETVVDLEIERRTFVDLGLPVPVNKPVLSSVNAKTRSPLPSFIPKDEKPINQDDLKVKLDEIIDAGKDSPHGDDITQGPITNASLSTCFSSSTNSQLARSPESPVNIKLERQLQHAATCCPLIHADRNVTRFPYCAASLSQYLSWSLMKRRAAEWQRALHITRCKECCHGDGMLVGVSYVARHLKSCNISSDLTTKQVMIWCRCYGYTPTPTLPSDQDLLYCCGCGTSELGASDGENVEEDSKEIHLTCHSMRKSPPDTHTTSVELIESLEARERELSRARTIDEEDEDVDVTSIPISRRLGICTQALTTLPTPITVEQLWIKDVCNEIGISLRPVVHHGVEVHAVESALFTLTRRFAEDLMRKALSLSSTSRSTLEPRVLVPGMIYAALRSMECWDFLTNVHTGHMVTDNTIAKNPTS
The following text describes a protein:
Function:
Vacuolar cation/proton exchanger (CAX). Translocates Ca(2+) and other metal ions into vacuoles using the proton gradient formed by H(+)-ATPase and H(+)-pyrophosphatase.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MAKENGVEDLEKSCLENQIVLPLLGNSANNHKKLLEKRAKSFTSRSSCSMPSGEICSKEGDAEVAKEVKDRGSVWAQLFLGFSEVVFGTKLCLLLLSIPFTFIAVHLELGRGYIFVSSLLAIAPLAERLGYVTEQLAFYTGPTMGGLLNATFGNATEMIISIFALRQNLIRVVQLSLLGSILSNMLLVLGCAFFCGGLCHRNEDQRFNQTAALVSSSLLLMAVMGLLFPAVLHATHTELHNFTSEISLSRFISVVMLVAYACYLFFQLKSHRQLYEEEPADGEEDEDEEESVLGYWNAIFWLGVITIVISVLSEFLVDAIEGTAETWNIPVAFISVVILPLVGNAAEHGSAIVFAMKDKLDISLGVAIGSSTQISMFVIPFCVVVGWAMGKDMDLDFEIFETATLFITVLVVAFLVQDGRANYFKGLMLILCYFIVGASFFGHMDLPDIPGVNSAKHFYSDALRLFSHELHHSATPST
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Sequence:
MGCGQSKDNSIDKQIVEMAKSKPITVMLLGSGESGKSTIAKQLKILFGGGFPEQERATHKSSICSNVVTCMRTLIEQSAILNHPMKYQPKSKEFTTEDPVTLPFSPELVGDVEALWADEGIQATYEESAKFQLPDCAKYLFENVKRIAMEDYVPTEEDLIHNRTKTTGIHEYDFVVKDIPFHLIDVGGQRSERKKWVSFFSDVDCAIFVTSLAEYDMKLYEDGNTSRLTESIAVFKDIMTNEFLKGAVKLIFLNKMDLFEEKLTKVPLNTIFPEYTGGDNAVMGAQYIQQLFTGKLQTEEMNISGADGTANIEGAVNEKVYTNPTNATDGSNIKRVFMLAVDVIMKNMAANGKMRPTK
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MRMDGSDFEDRKVSKPSPVLPFDVSNIGDLSQGVHSPLGISHFDSKNPTPFGRSTKNSVYEYETVTPYSRFKVDKKFGSATSVSPVHTKAEEPGLGLTPMNSADFSNKIASRYRS
The following text describes a protein:
Function:
Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids, to yield products up to 30 carbons in length. May also elongate diunsaturated fatty acids. Important for courtship behavior where it probably has a role in female pheromone biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MFAPIDPVKIPVVSNPWITMGTLIGYLLFVLKLGPKIMEHRKPFHLNGVIRIYNIFQILYNGLILVLGVHFLFVLKAYQISCIVSLPMDHKYKDRERLICTLYLVNKFVDLVETIFFVLRKKDRQISFLHVFHHFAMAFFGYLYYCFHGYGGVAFPQCLLNTAVHVIMYAYYYLSSISKEVQRSLWWKKYITIAQLVQFAIILLHCTITLAQPNCAVNRPLTYGCGSLSAFFAVIFSQFYYHNYIKPGKKSAKQNKN
The following text describes a protein:
Function:
The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein: it acts as a negative regulator of bone formation and is required to limit bone formation without impairing bone resorption or mineralization. The carboxylated form binds strongly to apatite and calcium; The uncarboxylated form acts as a hormone secreted by osteoblasts, which regulates different cellular processes, such as energy metabolism, male fertility and brain development. Regulates of energy metabolism by acting as a hormone favoring pancreatic beta-cell proliferation, insulin secretion and sensitivity and energy expenditure. Uncarboxylated osteocalcin hormone also promotes testosterone production in the testes: acts as a ligand for G protein-coupled receptor GPRC6A at the surface of Leydig cells, initiating a signaling response that promotes the expression of enzymes required for testosterone synthesis in a CREB-dependent manner. Also acts as a regulator of brain development: osteocalcin hormone crosses the blood-brain barrier and acts as a ligand for GPR158 on neurons, initiating a signaling response that prevents neuronal apoptosis in the hippocampus, favors the synthesis of all monoamine neurotransmitters and inhibits that of gamma-aminobutyric acid (GABA). Osteocalcin also crosses the placenta during pregnancy and maternal osteocalcin is required for fetal brain development.
Subcellular Localization:
Secreted.
Sequence:
YLYQTLGFPAPYPDPQENKREVCELNPDCDELADHIGFQEAYRRFYGTA
The following text describes a protein:
Function:
Required for maintenance of normal mitochondrial morphology as well as PCP1-dependent processing of MGM1.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Mitochondrion intermembrane space.
Sequence:
MTAICTDKTELNASWNTVSSAWLTRYPNPYSLHVVSADVLERYVDDEGRLYTERLLVKQGRLPRWASDLLNVNKSYILERSVIDPSKQELKSETFNLDHVKILRVIEYSRFIQSSENCSKTIVDTIAKFVSPLRFGLGRRVQKYSLKRFQEQLSSSRRGLLYVIQQKFQPS
The following text describes a protein:
Function:
Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
Miscellaneous:
MISCELLANEOUS: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
Subcellular Localization:
Nucleus.
Sequence:
MISGHLQTPDSSDHSGDEAKLTKPSGLESKTNELWSSDLEEELESRIMQPATFSSILKQFPSISEETIISKIMSNKNCDKNNWKKKIYCYRYFLQPSKEEPDVGNMKSLVEKLEKLKLKKWSASEIEQLFCNYLEDLTTSAVKVSIPGKTLDEVAAAVNNIHPRPRWTRKEIECLIKNENDFKKLEKDLFVRDLDSIKKKIRRDNLSIQNEIQDSEKKSPQSTDSNNKDSSRDLSRKERDQLKKLLSKPICFSELLAKFPGHSWEYIAREIIQLDSSEDNTIWLKKIYYYCVVYSISVDKEITKYIGGGNRIYEKVRSDWSKIKTLDFFKDWSLQEFERLYCFAFHDLTKSALTKNFPSKNLNDICKVVNISFPKVPYTDREMKYLERHLDTPMQTLENNLPFRSRGSIHKKLEALKALTETTEQKQPPTKTRPKNEEEKNVENAAYMKELIMFDLTLEAIENTFPSEPIEEIIKEIKNSEIFDPLSFTRGEKELMAKLVKKGNLIDDCFDYFPLREEEFIRSKYAEAEYVSGRKMKFNTPEERLAYEAKWTLFNMGKQEYGRGNRRSTKRYCEIDELSKLEQEASVKRSKKKIELTEEELEQRRKRSEHFRLCRLKKLEEKREKYRIEKAKRLEKIAAGLIKPSTSGYELKDIVTSAEYFQSIVGDKQKVQEGQKRKRIQTEYFAPEFIEKPKAVKLKTTKRQAEKNKIKKQLKREAQLKIKKKKTIAPKKGKRRVKTNNGIIEEIKDVYKLSSEPYVESEVEEEDEEEDYISPYDPPDIISDSQVKLNGRHLYISSFYKELPEIPELKFVSLPHMEMSGNDITVAKQIMTTANDDILYDDCLAYEIVAQHIKSYRDLPISFPPVLDPITHELNSANIVRIRFFLYPEHYESFMLASPKSNELDPVHEIAKLFMIQYSLYFSHSDTLKKIITEDYCHKLEHSVEENDFGEFMFVVDKWNQLVMKLSPNLASVQNILGLKEDINEAPRAYLNQQEVSIPTNSDLKIETFYDEIMYESASPLFNPINSNLEIDSESAPIPLGEVEIPNNVIEEINEKMPDNYIPDFFRRLKEKTEVSRYAMQQILLRVYSRVVSTDSRKLRSYKAFTAETYGELLPSFTSEVLEKLNLLPTQKFYDLGSGVGNTTFQAALEFGACSSGGCEIMEHASKLTELQAGLIQKHLAVLGLQKLNLDFALHESFVGNEKVRASCLDCDVLIINNYLFDGQLNDEVGKLLYGLRPGTKIVSLRNFISPRYRATFDTVFDFLSVEKHEMSDIMSVSWTANKVPYYISTVEETIPREYLSREETKETSGKSKSVSPVGEIENVAAAMMTPPTDSSESEIIKN