lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Note=Soluble forms produced by cleavage/shedding also exist; [Processed neural cell adhesion molecule L1-like protein]: Secreted, extracellular space, extracellular matrix.
Domain:
The FIG[AQ]Y motif seems to be an ankyrin recruitment region; The DGEA motif seems to be a recognition site for integrin.
Sequence:
MMELPLCGRGLILSLIFLLLKLSAAEIPLSVQQVPTIVKQSYVQVAFPFDEYFQIECEAKGNPEPIFSWTKDDKPFDLSDPRIIAANNSGTFKIPNEGHISHFQGKYRCFASNRLGTAVSEEIEFIVPGVPKFPKEKIEPIDVEEGDSIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMSQRGDLYFANVEENDSRNDYCCFAAFPKLRTIVQKMPMKLTVNSSNSIKQRKPKLLLPPAQMGSLSAKTVLKGDTLLLECFAEGLPTPHIQWSKPGSELPEGRATIEVHEKTLKIENISYQDRGNYRCTANNLLGKASHDFHVTVEEPPRWKKKPQSAVYSTGSSGILLCEAEGEPQPTIKWRLNGLPIEKHPFPGDFMFPREISFTNLLPNHTGVYQCEASNIHGTILANANIDVIDVIPLIKTKNEENYATVVGYSAFLHCEYFASPKATVVWEVADETHPLEGDRYHTHENGTLEIYRTTEEDAGSYSCWVDNAMGKAVITANLDIRNATKLRVSPKNPRIPKSHVLELYCESQCDSHLKHSLKLSWSKDGEAFEMNGTEDGRIVIDGAYLTISNITAEDQGVYSCSAQTSLDSTSEKTQVTVLGVPDPPGNLHLSERQNRSVRLSWEAGDDHNSKISEYIVEFEGNREEPGKWEELTRVQGEETDVVLSLAPYVRYQFRVTAVNEVGRSHASLPSDHHETPPAAPDKNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYKVSWKPQGAPEEWEEEIVTNHTLRVMTPTVYAPYDVKVQAINQLGSSPDPQPVTLYSGEDYPSTAPVIQRVDVMNSTLVKVTWSSIPKETVHGLLRGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDPFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPSFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYELGELNEINVTTPSKSSWHLSNLNSTTKYKFYLRACTSRGCGKPISEEGATLGEGSKGIRKITEGVNVTQKIHPVEVLVPGAEHIVHLMTKNWGDNDSIFQDVIETRGREYAGLYDDISTQGWFIGLMCAIALLTLILLTICFVKRNRGGKYSVKEKEDLHPDPEVQSAKDETFGEYSDSDEKPLKGSLRSLNRNMQPTESADSLVEYGEGDQSIFNEDGSFIGAYTGAKEKGSVESNGSSTATFPLRA
The following text describes a protein:
Function:
Cell death receptor specific for IGFBP3, may mediate caspase-8-dependent apoptosis upon ligand binding.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MGNCQAGHNLHLCLAHHPPLVCATLILLLLGLSGLGLGSFLLTHRTGLRSPDIPQDWVSFLRSFGQLTLCPRNGTVTGKWRGSHVVGLLTTLNFGDGPDRNKTRTFQATVLGSQMGLKGSSAGQLVLITARVTTERTAGTCLYFSAVPGILPSSQPPISCSEEGAGNATLSPRMGEECVSVWSHEGLVLTKLLTSEELALCGSRLLVLGSFLLLFCGLLCCVTAMCFHPRRESHWSRTRL
The following text describes a protein:
Function:
Exhibits a robust glutathione (GSH)-dependent disulfide-bond reductase activity toward the model substrate, 2-hydroxyethyl disulfide; the actual physiological substrates are not known. Also displays a modest GSH-dependent peroxidase activity toward several organic hydroperoxides, such as cumene hydroperoxide and linoleic acid 13(S)-hydroperoxide, but does not reduce H(2)O(2) or tert-butyl hydroperoxide at appreciable rates. Exhibits little or no GSH transferase activity with most typical electrophilic substrates, and has no detectable transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) with glutathionylspermidine (GspSH) as the nucleophilic substrate.
Miscellaneous:
MISCELLANEOUS: Binds two molecules of GSH in each active site; there is one tight and one weak binding site for GSH.
Sequence:
MTDNTYQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHPLQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIPALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRTNGPLNEQLHERHDASDFETNTEDKRQG
The following text describes a protein:
Function:
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
Subcellular Localization:
Cytoplasm.
Sequence:
MHEKGFRVSKVVLLYNRDRERSYRIFERLRSSLLSNEIEVVEDHREAEVAVVIGGDGTVLRAFHQVGSLPILGVKDGTFGTLLEFDSTQLDIIPEILREGEFWLEHALTLEIIDSKLSLIALNEFLVRSGKLGKSSRLGLAIDDAPLGECICDGIIVATPTGSYAYSLAAGGPVLDPRCDNIAISYVAPWPPSLVPAVRSIVVPSSSVVEVWSTSPFLYVVADGLSPVRLRPPLRISRSRREAVFIRKSPDPTEFYKRMVKRMIPKTLTGILHYEKLRPAPAKSLNLDGADQ
The following text describes a protein:
Function:
Active thioredoxin with a redox potential of about -250 mV.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDTTFLESDCDEQLLITVAFNQPVKLYSMKFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTIFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH
The following text describes a protein:
Function:
Responsible for the anti Gram-positive activity of immune hemolymph.
Subcellular Localization:
Secreted.
Sequence:
MKCATIVCTIAVVLAATLLNGSVQAAPQEEAALSGGANLNTLLDELPEETHHAALENYRAKRATCDLASGFGVGSSLCAAHCIARRYRGGYCNSKAVCVCRN
The following text describes a protein:
Function:
Cytochrome P450 monooxygenase; part of the benzoic acid degradation pathway also known as the protocatechuic acid pathway. Benzoic acid debradation begins with the conversion of benzoic acid into 4-hydroxybenzoic acid through hydroxylation by the benzoate-4-monooxygenase bphA, and its partner NADPH-cytochrome P450 reductase cprA which act as a mediator in electron donation from NADPH. 4-Hydroxybenzoic acid is then converted into 3,4-dihydroxybenzoic acid (also called protocatechuic acid) by the p-hydroxybenzoate-m-hydroxylase phhA (Ref.5). Protocatechuic acid is converted into 3-carboxy-cis,cis-muconic acid by the intradiol ring-cleavage dioxygenase prcA, which is further metabolized through the 3-oxoadipate pathway to finally enter the tricarboxylic acid cycle (TCA) (Ref.5).
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MLALLLSPYGAYLGLALLVLYYLLPYLKRAHLRDIPAPGLAAFTNFWLLLQTRRGHRFVVVDNAHKKYGKLVRIAPRHTSIADDGAIQAVYGHGNGFLKSDFYDAFVSIHRGLFNTRDRAEHTRKRKTVSHTFSMKSIGQFEQYIHGNIELFVKQWNRMADTQRNPKTGFASLDALNWFNYLAFDIIGDLAFGAPFGMLDKGKDFAEMRKTPDSPPSYVQAVEVLNRRGEVSATLGCYPALKPFAKYLPDSFFRDGIQAVEDLAGIAVARVNERLRPEVMANNTRVDLLARLMEGKDSNGEKLGRAELTAEALTQLIAGSDTTSNTSCAILYWCMRTPGVIEKLHKVLDEAIPQDVDVPTHAMVKDIPYLQWVIWETMRIHSTSAMGLPREIPAGNPPVTISGHTFYPGDVVSVPSYTIHRSKEIWGPDAEQFVPERWDPARLTPRQKAAFIPFSTGPRACVGRNVAEMELLVICGTVFRLFEFEMQQEGPMETREGFLRKPLGLQVGMKRRQPGSA
The following text describes a protein:
Function:
General sensor of environmental conditions, such as heat stress, effecting changes through pkaC. Essential for survival to nitrosoative and oxidative stresses. Required for cell cycle control, not only at the onset but also during development (aggregation process and postaggregative development).
Subcellular Localization:
Cytoplasm.
Sequence:
MGSTTQMSDYLVSTTTTSSASSMVTMTSQIENNSLNSNDNTNTTNNNNNNNNNNNNNNNNNNNNNNNNNINNNNNNGGMVGVNHKTHKKTASIGGGKNRAILHDFTFSYFIPNQNRSEDNSNENELGLNNHNVQHQGPIIHLTKNLLHFYKKCNSNFNYISSLNPRRVLTHPSEPLSNDGYDNVNSDYIVYVNDIITNNESGQKYKVLDSLGQGTFGQVVKCKNCDTDELVAIKILKNKQAYFQQGRLEIQTLKSLNDQHDPEDKNHILRLLDSFIHKMHLCIVFELLSVNLFELIKQNNFRGLSTNLIKVFLIQILDALIVLANANIIHCDLKPENILLQNVNSPAIKIIDFGSACYEKSTLYTYIQSRHYRSPEVLVGTVYCASIDMWSLGCISAELFLGLPLFPGNSEYNQISRIVEMRGIFPSDLLDKGKSSTRYFHRHLGSNSDDNNNNNNNNNGKPYYYTLKSEEDYQRDSKTTLLPSKKYFNYKTLPEIIQNYGFKKSMSPQDIEKEKQHRIVFTDFINGLLQLDPNERWSPMQAKEHPFITGQPYNGPFIPDPSKKRHFTYSQPKQIPQHSMLNGNQILNQHQLFQQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHNQFQQQQQQQQQQQQSSSQQHIQIQPLQLFSTPYTSTNNTPNLSSSNSGSSLNNLKKLNLPPFKQQQQQQFSTSQNSDSFNFPNESFSPRGIYIPSSASNIQQQQQPININNNQNGVGSQVSQLALGQSPSLFGTPTNIYPPYSSMYNNSPVATPNSLSFYGSSWGSDSSSISLNPSTPTQKQMFQQQQYSNNNNNNNNNNNNNSNNNNGNNTNNINSNNNNNNVNRRNRSKSDIPSDSFSSSEGMDPQFNLYQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQYQQQFQTLQDLNIEGEKPPIYPNSPHRKRSHSGYLDQYANGYNSQQTNNTQQQQQQQQQQQQQQQQQQQQQQHPSFFSTRMHLDHFNGGSRYRSQSYGDQQFQQQQYKQQQKNLHHQQQQQQRFMQVGSPPTSHLSPPIPQSPLMMSQPLHQTYIPQQQQQQQQQQQQSQPTPFTPQMISQEPISPALMGDASSIWNPSPTEELLFTIDLPNQQNTPHLTPSNSSTNLLGKSASSPLKNSSGGAIPPTPTIPINMEEINNGFSKFHFNDQPSWNSNGNSPWMIQQQQQHQQGFNGNSESMYNDDLIGFSPYNNYSNDYRPQLFNKQSPPSSYNSNKSFYGGSGGGGNNNNNNNSRPTNQNFSNSLLPSQQQNVIFPQNSPPSSYNSSNSLSKSGGNTVKNNSNTGGRPRGDSMKQRFNSTNNLLSGGSYQYQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQYKKDTPSLMMSPPMNGLKTSSEIGIPSEEIRYQYQQQQLQQQFQQQQQQQQQQQIQQQLQQQQAPPQNRKQVVIGSYRET
The following text describes a protein:
Function:
Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway.
Miscellaneous:
MISCELLANEOUS: [Isoform 3]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MRRLPRALLLQLRLALLVAAGAPEVLVSAPRSLVWGPGLQAAVVLPVRYFYLQAVNSEGQNLTRSPAGETPFKVVVKSLSPKELVRIHVPKPLDRNDGTFLMRYRMYETVDEGLKIEVLYGDEHVAQSPYILKGPVYHEYCECPEDPQAWQKTLSCPTKEPQIAKDFASFPSINLQQMLKEVPKRFGDERGAIVHYTILNNHVYRRSLGKYTDFKMFSDEILLSLTRKVLLPDLEFYVNLGDWPLEHRKVNGTPSPIPIISWCGSLDSRDVVLPTYDITHSMLEAMRGVTNDLLSIQGNTGPSWINKTERAFFRGRDSREERLQLVQLSKENPQLLDAGITGYFFFQEKEKELGKAKLMGFFDFFKYKYQVNVDGTVAAYRYPYLMLGDSLVLKQDSPYYEHFYMALEPWKHYVPIKRNLSDLLEKVKWAKENDEEAKKIAKEGQLMARDLLQPHRLYCYYYQVLQKYAERQSSKPEVRDGMELVPQPEDSTAICQCHRKKPSREEL
The following text describes a protein:
Function:
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Sequence:
MRKMNLIVAMDAEGGIGKNGVLPWRIKKDMQYFASVTKNVSDQSKRNAVLMGRKCWESIPVTRRPLAGRLNIVLSRQLPAQKSDDYIVVNSLEAAMKLLSEPPFVDSIETIWNIGGAEIYDLALRENLVDEIHLTRIFKNFEADVHLKSLDFSKMEKVQNAEVSSENSEIFEENGLKFEFCKWKVVENH
The following text describes a protein:
Function:
Major structural component of sperm fibrous sheath. Plays a role in sperm motility.
Subcellular Localization:
Cell projection, cilium, flagellum. Note=Localizes to the principle piece of the sperm flagellum.
Domain:
RI-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.
Sequence:
MIAYCGTTTMSDDIDWLHSRRGVCKVDLYSPKGQQDQDRKVICFVDVSTLNVEDKDSKGAAGSRSEGELNLETLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDLQKYALGFQHALSPSASSCKHKVGDLEGDYSKIPSENCYSVYADQVNFDYLNKGPQNLRLEMAASKNTNNNQSPSNPATKSPSNQRSVATPEGECSMDDLSFYVNRLSSLVIQMARKEIKDKLEGGSKCLHHSMYTSGDKGKTSPRSAVSKIASEMAHEAVELTSSEMRGNGEDCRDGRKTFLYSEMCNKNKCGEKQQMCPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSCGKPIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGKQNAADIMEAMLKRLVSALLGEKKETKSQSLAYATLKAGTNDPKCKNQSLEFSAMKAEMKGKDKCKSKADPCCKSLTSAERVSEHILKESLTMWNNQKQGNQGKVTNKVCCTSKDEKREKISPSTDSLAKDLIVSALMLIQYHLTQQAKGKDPCEEECPGSSMGYMSQSAQYEKCGGGQSSKSLSMKHFETRGAPGPSTCMKENQLESQKMDMSNMVLSLIQKLLSESPFSCDELTESDNKRCCDPRSSKAAPMAKRPEEQCQDNAELDFISGMKQMNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQAALVGSGSRCGRDAMMSQNYSETPGPEVIVNNQCSTTNLQKQLQAVLQWIAASQFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAKERQLDEAVGNMARKQLLDWLLANL
The following text describes a protein:
Function:
Protein disulfide-isomerase involved in chloroplast development in cotyledons. Involved in the process of vesicle-derived thylakoid formation, probably at the level of the integration and folding of LHCB proteins at the initial location of integration. Acts only in germinating seeds after dormancy, during the transition from heterotrophic to autotrophic growth.
Miscellaneous:
MISCELLANEOUS: Its sequence is related to the DnaJ family but lacks the J domain. The CR-type-like region is similar to CR-type zinc-fingers.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein. Note=Associates with multiple thylakoid complexes.
Sequence:
MFRLYPNCSLPSHRPLVFLPRLPSRSLRCRAAADIPLGDGIRLPREADSTSDTARSRDVSVAAGGNGEGAKWRKRRLLWSKSGESYLVDDGDALPLPMTYPDTSPVSPDVIDRRLQCDPVVEDCREVVYEWTGKCRSCQGSGTVSYYKKRGKEVICKCIPCQGIGYVQKITSRTDIEVMEDLDNEPS
The following text describes a protein:
Function:
Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore. Essential for the production of 11-cis retinal for both rod and cone photoreceptors. Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MSHQVEHPAGGYKKLFETVEELSSPLPAHVRGRIPPWLAGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKDGRVTYHRRFIRTDAYVRAMTEKRIVLTEFGTCAFPDPCKNIFSRFFSYFRGVEVTDNALVNIYPVGEDYYACTETNFITKINPETLETIKQVDLCNYVSVNGATAHPHVENDGTVYNIGNCFGKNFSIAYNIIRIPPLQADKEDPMNKSEVVVQFPCSDRLKPSYVHSFGLTPNYIVFVETPVKINLLKFLSSWTLWGANYMDCFESNETMGVWLHVADKKRGKYLNNKYRTSSFNLFHHINTYEEDNFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKRNAKKAPQPEVRRYVLPLAINKADTGKNLVSLPNTTAAAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYAFAYGLGLNHFVPDRLCKLNVVTKETWLWHEPDSYPSEPIFVSHPDAQEEDDGVVLSVVVSPGAGQKPACLLVLNAKDMTEVARAEVETNIPVTFHGLFRRS
The following text describes a protein:
Function:
Has a role in karyogamy, recombination and segregation during meiosis. Although it has been shown to associate with the spindle pole body it is unlikely to be involved in its formation or maintenance.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Associates with the spindle pole body (SPB).
Sequence:
MLNERDFDLIFDSYDFKHEGKVHLSNFLPIINDLQLLHPASAPPLLSEFQKQCTLEFVRQNADLSITKDNFRDVYKKLTENEDDSFANQAEKPSMEQQNSKNSIKEDANEHSVNSAHSKSSSNASPESLNPSQMMSKRLSLPPMSQFTDSDFVNILRTPFAQSTPLNRNTSSRNTEMPLVRKDKPDFSNGHHDLIKQITELQDMLDKARDQARKKSRTVDILEGKVNELTHQLNMADSKYNESKVANNSQNNQIKTLKAQNLNIHKNFQKIQSELIQTNSGLYSTKKELSALQVRYATLLRKFTDQTKKIEELSLAASRSSENENTIRRLALENHELKNSNNQLNNHIDDLTREKHLIALSNNPKGDEFLSPSNLDEMVYSKEVGLSFTQPSVCISIPAVGMRESEELRELEFKCKQQKKTIEECKHISQSLQSSLTAESSRNKELVAGFLMLSEEIGIQKWIIQSLSKMSPTLNDFCRRYDSSMPTYEESSHECTVLSSFSDDETGLMATNTTMNNSSKDFMASQDTVNADNPHFLATKGQPLLLLSVMKSNILRLFYVLFLFACFYGLDYILCAELLQAFLRVVFTFCEHIIILLYGRYELVQPS
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation; Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein.
Sequence:
MAERRVAAIAPSRTELSLVRFENVGLRYGLGPEILRDLNFQIPAHSFQFLTGPSGAGKTSLLRLLFLSHRPTRGLVNLFGHDISQLGKDEIADLRKRIGIVLQDFRLLDHMTTYENVALPFRVMGRSESSYRKEVIDLLRWVGLGERMDALPPILSGGEKQRAAIARAVISRPQLLLADEPTGSVDPTLGRRLLRLFIELNKSGTAVIIATHDIGLMDQYEARRLVLHQGRLHVYE
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MDDIETRVRKLVAARFGVEECDIRLDSDFRNDFGAESLEVVELVMALEAEFGVEIADDDAERIETVRQAIDYLEEAVPT
The following text describes a protein:
Function:
Required for meiotic chromosome segregation.
Subcellular Localization:
Nucleus.
Sequence:
MNQDDFRKLLATPKAETSQLKNFSSNKSQRLVFGRKHKTAKLEAPRALIKRKQLSHSTSSDITRHSNAKNSGKDTQFYEEPSSKQDIELHKLHEKLRNGQITTKEYSEKSKELGGDLNTTHLVRGLDRKLLEKVRSNELALDDSLLSSSEKEVDEEADKLLEKVAEESSHPESVSILEEKKKIPLYPNGQPKYRKILENGKKVKYLLDENGEILKRLVKKEKKLKNDNERLENEHRTEKLNVNANSLGKSFVKHDIPLPPVDLKLDIFEEVGEYDPFHENDKEPAELKAKDAFQLKGHHELDAPYHKKVFDTNQYSDLKPTNFMSQIHRLAKVQERKEEEERKKGKDGQIVDAGFGLVLSKDDTADIHELGESDDDDNVKRRKTKG
The following text describes a protein:
Function:
Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
Subcellular Localization:
Periplasm.
Sequence:
MQTLKRGFAVAALLFSPLTMAQDINAQLTTWFSQRLAGFSDEVVVTLRSSPNLLPSCEQPAFSMTGSAKLWGNVNVVARCANEKRYLQVNVQATGNYVAVAAPIARGGKLTPANVTLKRGRLDQLPPRTVLDIRQIQDAVSLRDLAPGQPVQLTMIRQAWRVKAGQRVQVIANGEGFSVNAEGQAMNNAAVAQNARVRMTSGQIVSGTVDSDGNILINL
The following text describes a protein:
Function:
Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels. Acts as a gatekeeper of zinc release from intracellular stores, requiring post-translational activation by phosphorylation, resulting in activation of multiple downstream pathways leading to cell growth and proliferation. Has an essential role in B cell development and is required for proper B cell receptor signaling (By similarity). Plays an important role in maintaining intestinal epithelial homeostasis and skin dermis development by regulating ER function. Controls cell signaling pathways involved in glucose metabolism in skeletal muscle (By similarity). Has a protective role against ER stress in different biological contexts. Mediates Zn(2+)-induced ferroptosis (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Sequence:
MARGLGAPHWVAVGLLTWATLGLLVAELGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHGHDHGHSHGDLHHGHSHGHSHESLYHRGHGHDNEHSRGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAHSHTHGSHGHGRQECSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVVMMVLIAHLE
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
Subcellular Localization:
Cytoplasm.
Sequence:
MTVWVGLTGGIGSGKSAAAQCFADLGVPRIDADAAAHSLTASDGIALPEIRRLFGDTVFDTQGLLRRDILRKEVFASPSRKALLESVMLPLIFSEIKKQQETFTDAAYGIVEIPLLTEKRQFISLIRRVLTISAPVEKRIGRVMARSGLTRGEVAAVISHQASESERLLLADDVLLNDGSLKSLREKTMRLHAFYSGIFASKPTQGKHND
The following text describes a protein:
Function:
Probable carboxypeptidase.
Subcellular Localization:
Secreted.
Sequence:
MISQTHSCVVIATIIFFVTVGVNSISEVDKISSLPQQPKVGFQQYAGYITVDEVQKRALFYYFVEAEVEPASKPVVLWLNGGPGCSSVGAGAFVEHGPFKPTKNGLIKNDYSWNKEANMLYLESPAGVGFSYSTNESFYDSVNDYLTARDNLIFLQHWFTKFSEYKNNEFFITGESYAGHYVPQLAQLIVQTKSKFNLKGIAIGNPLLEFNTDFNSRAEYLWSHGLISDSTYDSFTKICNFSQIRRQYANGALTTVCARVNRLVSMEVSRYIDSYDVTLDVCLSTVEQQTYVLTQLQEGEKIDVCVEDETFTYLNRKEVQEALHAKLVGITTWTTCSGVLKYNMQNLEIPTINILGTLVKSGVRVLVYSGDQDSVLPLIGTRSLVNGLAKDIGLNTTESYRTWFNGRQVAGWTQVYGDMLSFATIRGASHEAPFSQPGRSLVLLKAFLEGKSLPTIL
The following text describes a protein:
Function:
Receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.
Subcellular Localization:
Secreted.
Sequence:
MPKHCFLGLLIMLLTTATETQPAHVSLKPQKVQFQSRNFHNILHWQPGNSLTSNGSVYFVQYKTYGQGQWKDKNDCWGTTALFCDLTKETLDPYEPYYGRVMMAWAGSYSEWTRTPRFTPWWETKLDPPVVTITRVNASLRVRLRPPELPHRNQTGKNTSMENYYNLVYRVSIINNSLEKEQKAYEGTQRAVEIQGLTPHCSYCVVAEMYQPMFDRRSPRSKERCVQIP
The following text describes a protein:
Function:
Involved in the negative control of telomere length and in telomeric silencing through a replication-mediated pathway. May have a role in Okazaki fragment maturation. Required for S-phase progression. An RFC-like complex (elg1-RFC) is formed where elg1 replaces rfc1 in the RFC complex. This complex appears to have a role in DNA replication, replication fork re-start, recombination and repair.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MQIVGYLSADSQSNPDLKSENEAKEEKPIGRRHTMSPVPATSENKYFGKSPLSGSRKPRRSRSLHKERSYMRKFFDMDMEESKDFENDQSLLVTLKVSTSLGQKIENILHPKLSNDTNSTAFPPAKSSGEASDTNILVENINSQETVNSSPLVSELHYSNLADSPSNLRNTVTSMHPFFMSKSVKKNSEIKFVSEERGGTKPERLLDPLWPTPDSQSMLEYAGSIEPSVFWFPKKHLEEAILEETSHLSFKEVLSSTTANMITPLAEKNKTEVLQVTPSKLHTFALESLCFSPAPFIQKVLSRLLPSDPNVEMPMIPQILEKGLWVSKYAPSKTQDCCAFSQCLSKIADWLRSCRLTKPESSSVPPSSSISRSSTIHSCTSSKRNEDSLSESDFEPDIIEEEDDSDEFNPSVSRKKAKLTSSQFSNWMLVTGVTGIGKTSCLYAICRELNFEVVEIHPGMRRSGKELLERIGELTQSHIVDKSRLNNTPDILILLEEVDILFQDDRGFWQAVSTLIEKSKRPVVMTCNETDFLPSAFLQEDHIVQFQSISSALLTDYISSVLYADRCIISRNVVESISYRYGSDLRGILMQLNFWSLVNFPSLPSKDKQDDSHEPFIEATISAFDEGVGVYNPRIQTSEDLLQTYSEEQMGDIGLLFMPNLVNWRKVCVPKSEMEEKEAIMEKLIYSHQYADSLSYVDYRFSSQPTIYETYELMNDSASFEDMSLECRDNCANAFQDNLVGFPTISNPFHANAPPEPHELKLQYHSFCFINNLFSKSSLKAISSNDSIVPKALNNRELQLSALASTIGYKLDPDDVYNILSFLSFANSQVTSYTPPNSIDRPNDILILEVAPFVRCMRRYDRIRLNSYKLLLSSKGRSASHISRRGAASILRSAGYNYGRLQYLEGSDRILSTWFSTTLD
The following text describes a protein:
Function:
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2 (By similarity). Involved in the control of rRNA expression. Required for embryo development and female gametogenesis.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAPNATGVLKRHRSHEKFDKKRDTKKHKHVEKTIVSNPSTDSPEESSIEAESEAMVYREPTQYQNLLVSLGSSNKVVADMNKRRQREEEGKSDTEEDEDDEDEDEEENSGSDDLSSTDGEDDKSQGDDQETLGGLTDDTQEDNDNQSEEEDPDDYETDEEVHELSTNGQSFVDASSSISAFSEHLSHKLSSEEVETLPKGKWKFKWESPAFDMPNCKWKGTSENFLDGIQSDAPYGLKPKLYNHWLQLYKKCGGKDLDSSKRRKFFSICNSYLDILHSNKKPFYHCGSDEDSSAMDAYLMHSLNHIFKTRDLVKKNESKIAKHRETSEEEILSDDGFLDQGFTRPKVLILLPLRSIAFRVVKRLIQLTPESQRVNVEHLDRFNDEFGCEEDTDDCDGEKTTSKNGNSIKQKSSKPSDWQALFGANNNDDEFMLGIKHTRKSIRLYGDFYSSDIIVASPLKLHMAIGAAEENKERDVDYLSSIEVLVIDHADIISMQNWSFLATVVDYLNRLPTKQHGTNVMRIRPLYLDGHARFYRQSIILSSYLTPEMNSLFGRHCLNYKGKMKMACEYKGVLEKVLLPVRQIYERFDAASITQVDDARLEYFTKKIFPKIKDSVQGGVMIFIHSYFEFVRLRNFLNTQNTSFCLLGDYAKNADISRAREQFFVGSRKIMLYTERAYFYKRYKIRGIKNLILYSLPERKEFYPEIMNMLEEGSHDMMSTALFSRFDMLQLERIVGSTSAKRMITSEKNMFAFC
The following text describes a protein:
Function:
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
Miscellaneous:
MISCELLANEOUS: Present with 172 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSDSSVREKNDNFRGYRKRGRQELRKIKRSSARTEGGSTETLEDVAEDIDHRSDEDEVSDVDSGDDFDIEDEEGKKEKVYDALLTILKSEHPEPKRRRREADESNKAPAEVGEDEHENTEHGPVDDQLEIENGLLGNHEDDNDDDSSGDEKDIDSEDEQDPFESHFNQVPEKFVDKLSNAFKTKSVKYKSVKGSLSDSESYIYAKPVVIGEEALVESPYRSSSIYSYFLKQRLKVQNGLLDKKTDPLTALQKKLVDPMFQYKDILYEYDSYEKDEDEYRDLYALHVLNHIYKTRDRILKNNQRLQDNPDTEHLDQGFTRPKVLIVVPTREVAYRVVDKIISKSGIDQVDKKGKFYDQFRDDSLPPKSKPKSFQHIFRGNTNDFFVVGLKFTRKAIKLYSNFYQSDIIVCSPLGIQMILENTDKKKRQDDFLSSIELMVIDQLHSIEYQNISHIFTIFDHLNKIPDQQHEADFSRIRMWYINEQAKLFRQTMVFTKYISPAANSLINGRCRNMAGRWKNHKVIGSENSSIGQSGLKIRQIFQRFDIIGNSIIEEPDYRFKFFTSVIIPGIVKSTGYEDGILIYIPDYTDFIRIRNYMKEKTTILFGDINEYSSQRQLNANRSLFQQGRLKVMLYTERLHHYRRYEIKGVKSVVFYKPPNNPEFYNEVVRFIGKNAFLGNTDLNISTVRCIYSKLDGLSLERIVGTKRAAVLSHAQKEIYEFK