lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Hydrolyzes acetyl esters in homogalacturonan regions of pectin. In type I primary cell wall, galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions. Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MVTHCLFFFISLLIIIICRTESLLVNITILESAVATGAVCLDGTPPAYHLDRGSGTGLNNWVISIEGGGWCQNITHCLERKNSRLGSSAKMGKQVAFSGIMSNDPKFNPEFYNWNRVSVRYCDGGSFTGDVEAVDPATGLHYRGARIFKAIMADLLSQGMSTAENAILSGCSAGGLASILHCDNFRALLPKSARVKCFSDAGYFVNLKDISGEAYIEEYFNDVVTLHGSAKNLPPSCTSKLKPSLCFFPQNVAHQLQTPLFIINAAYDHWQVRNILVPSTADPTGAWTNCKADMRNCTLSELKVLQGFRLNFLKVLEGLGPSSTRGYYINSCFSHCQTQQQAYWFGPNSPRLFNKTIAEATGDWFWERNQFQEIDCPYPCDKTCVEDSTIAVVR
The following text describes a protein:
Function:
Zinc metalloprotease.
Sequence:
MTYRSCIPQNDLECYYNPNKTKYKSTNILSSIQHKIDKELTAYITDKTIDDTFGNRMIVFRDSFYDKPKNSKIFRQIIHMIETSNCWYSVKFLMDNGISSLFSLGITPHHTYPKKYYPMIISPILSLESKNDYQDYLALVRLKNFIGYSYDYITKYWNYKLSNKQNFINDVMEMESQLSLVTLTIEQQNNPFVIYNSLKWREFLEKYDVDNFWSSILGSYLKKEDYVIFDNIQYLSYLREYLKNTSKNSIKNYLVYSLVKKFGLYTDLLEFYNDIVIESINHDQIFLNMFSQYFGIYLETVFETRYHDKDKKEYITKMFYDMKLYLRNYFIECKFTDKTKREISLKIDNLHMVIGRQNYQYDLENFPLMGNDFYENVLNLERYYFHESIKLIGSTINKEWFSINGGMYSFEVNAYYDPICNVLYIPTSIINDMTISLERDDVYNYGSIGTILAHEIMHSLDNFGLQVNCDLSIGNKWDISDYKFYLSDLRKIIQHRIKLSNYDIASSIDALSEDISDTLGLKLSFKTYLSKFNKKIEPDNLSTNDKIHLQKFFYSWTETFKNINNNNQDDHSPSYIRINAPLAHLDEFYYLYGVESQHLNYLDPQLRSRILDKIN
The following text describes a protein:
Function:
Mediates the hydrolysis of steryl esters, thereby playing a central role in lipid metabolism. Under heme-deficient conditions, it constitutes the major steryl ester hydrolase, suggesting that it plays a central role in mobilization of steryl esters under anaerobic conditions.
Miscellaneous:
MISCELLANEOUS: Present with 7770 molecules/cell in log phase SD medium.
Subcellular Localization:
Lipid droplet. Membrane; Peripheral membrane protein.
Sequence:
MGVSAVLKRARNLLATFIVCCFMAVVLVLALAHHFINEHRDTRSSSTQIEVDDESKRNVHHDHVLTRTNAYATPYLDLEHDKKNGIVYDHTRTVVRKKNHEVGSSSLHKNLFHKFLTKLIFRFIEKEKVTEGVTQGKFNNSSNEIANHEPVFEKIPVQCDNPLQNLILSEDLTLVADLNYYFNQYNIQIEEFRLETEDGFVIDLWHLIPKYRTTDSDKKKRPPILMLHGLLQSSGSFASNGRKSLAYFLYQSGYDIWLGNNRCGFRPEWNEAKVPTLASRWDWDLREMVKYDLTLLIDTVLAKTQFEKLTLISHSQGTTQGFMGLVNEDKFFPPGSGSKESFFTSKIANYIALAPAVYPGPLLNEKLFVKLMTKEIENPWFFGETSFFEIMMIVRNLCVGESLFSFVCYTIFNYLFDWNDTLWDTALRDRHFLFSPVHVSVKLMQWWLSPDPNKVSFKFGSHKMFPDNVKWFSDASKAPNIYLFVPKQDRLVDGERLINHFVNVESNVNYKIWYIDEYAHIDVLWAHDVIERIGKPILQNLNNYYSKKPSSAFESDCSDTEVETELEMVAEKA
The following text describes a protein:
Function:
Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
Subcellular Localization:
Secreted.
Sequence:
MRLFPAIFCLAVIMRVRGKEPAPHPQFLDPRDAINLGQDWGHGFPAGTVLIDLLNITSSSSSFEVQTFDPEGVLLFGDSRGGHDWFLLGLRAGRPEIHIHNQMAKVSVSGGPKINDGKWHKVAVRSQEHRIVLEVDGQEALRIGHVSEGVTSSLDTTMRIAVGGILTNSSELMEPLHIPLDACLRHWVFLGVTPKWLLDPTFLPHPKRCFASQRSGSYFPGSGHVAYRTSDLPAALSQTGGPWALSLQMDLFSESHVFPLLRVSHPETGTLLFLRGQDRNLVVELGNNTILTQQMPDVGSSEGYKFHLTITPKSVTLQSGDEKESADISEGEYTALRGSWIHHEGVLYIGGAQRAEEESPGHFRGCLQNIVVQGSLLDLDSASYKSNSVWAHSCPLPTPQG
The following text describes a protein:
Function:
Binds to the cAMP response element and activates transcription.
Subcellular Localization:
Nucleus.
Sequence:
MMNVDQDRPFVCIAPGCSQSFQREDHLIIHRHKHEMTLKFPSIKCDSMLSDQTPTPTRFLRDCEEVGLFTDLELNQSQTEEQTKPNFSAQTSAQRQPHTETQPEQGQHQQFQPQQQQSCALAHLNQNQLQTHSSQCQSQCTATYSSSNKQSAPSCLHSRQTNTVKSNMNMESQMSMNSSIIGIPGPAHSGSCSSVQRSKVIPAHSQPAVSNGSQNPLCHMMEMMPSQPHPLSHLQSASHHHASYQQHCHSQSPQRLAHQHQSQDQSHHSHAHHSTPSHLPLGPSHQNAPPLSHQPIPIQMSSTPKQSHCPQSPPQPATGRRRRTAEDDPDERRRKFLERNRAAATRCRQKRKVWVSSLERKAEELTHTNLQLQNEVTSLRTEVTQLKQILLTHKDCPVSVRQRETQSGIGSPTGSPVHSHAIQHNSISTSSTLPRGHLTTHSHSTSNTQL
The following text describes a protein:
Function:
Transcription factor that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') and displays two biological functions, as regulator of metabolic and redox processes under normal cellular conditions, and as master transcription factor during integrated stress response (ISR) (By similarity). Binds to asymmetric CRE's as a heterodimer and to palindromic CRE's as a homodimer (By similarity). Core effector of the ISR, which is required for adaptation to various stress such as endoplasmic reticulum (ER) stress, amino acid starvation, mitochondrial stress or oxidative stress. During ISR, atf4 translation is induced via an alternative ribosome translation re-initiation mechanism in response to eif2s1/eIF-2-alpha phosphorylation, and stress-induced atf4 acts as a master transcription factor of stress-responsive genes in order to promote cell recovery (By similarity). Promotes the transcription of genes linked to amino acid sufficiency and resistance to oxidative stress to protect cells against metabolic consequences of ER oxidation (By similarity). In the absence of stress, atf4 translation is at low levels and it is required for normal metabolic processes such as embryonic lens formation, fetal liver hematopoiesis, bone development and synaptic plasticity (By similarity). Acts as a regulator of osteoblast differentiation by promoting expression of osteoblast-specific genes (By similarity). Regulates the circadian expression of the core clock components. Mainly acts as a transcriptional activator in cellular stress adaptation, but it can also act as a transcriptional repressor (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSLCVGDAGALLLGPWPLTADPQGPLLDQDEESSVLEGSWSPSSSSLSSFSPPASGDAPSELLSLSWQPSDVLLTEQSTAGDVFPGMDWMTEKLDLNDFDLDSLIGSCDSEDSPGSPEDLLACLDSSMDLDLDSLPFGSADLDLPLGLDLPLPEEIKSEPLSPAPSVPSPPEEAPQDEHTEVPVLHPAGIMLSLSPSHIVVLLTPKEEQNISDCSDSDSGISVSGSPAHQSDLEPSSRAKPYSRPDPEASPALKGRVKTSSGAPKVEKKLKKMEQNKTAATRYRQKKRVEQESLNSECSELEKKNRELSEKADSLSREIQYLRDLLEEMRTAKQRKSKR
The following text describes a protein:
Function:
Has insecticidal activity against the locust M.palpalis. When administered orally to locusts at a low dose it causes them to lie on their sides exhibiting sporadic limb movements and muscular twitching, followed by full recovery. When administered at higher doses the same symptoms are observed, followed by death.
Miscellaneous:
MISCELLANEOUS: The Gly-rich repeats may be important in the extracellular secretion of this metalloprotease.
Subcellular Localization:
Secreted.
Sequence:
MQSTKKAIEITESSLAAATTGYDAVDDLLHYHERGNGIQINGKDSFSNEQAGLFITRENQTWNGYKVFGQPVKLTFSFPDYKFSSTNVAGDTGLSKFSAEQQQQAKLSLQSWADVANITFTEVAAGQKANITFGNYSQDRPGHYDYGTQAYAFLPNTIWQGQDLGGQTWYNVNQSNVKHPATEDYGRQTFTHEIGHALGLSHPGDYNAGEGNPTYNDVTYAEDTRQFSLMSYWSETNTGGDNGGHYAAAPLLDDIAAIQHLYGANPSTRTGDTVYGFNSNTGRDFLSTTSNSQKVIFAAWDAGGNDTFDFSGYTANQRINLNEKSFSDVGGLKGNVSIAAGVTIENAIGGSGNDVIVGNAANNVLKGGAGNDVLFGGGGADELWGGAGKDIFVFSAASDSAPGASDWIRDFQKGIDKIDLSFFNKEANSSDFIHFVDHFSGTAGEALLSYNASSNVTDLSVNIGGHQAPDFLVKIVGQVDVATDFIV
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
Sequence:
MGESQSSEDASRFRALGNGVSGAGQGSAGDNELHDGSIASQAVRAYPNGGRSLVSDVGLFDTLRVGSNQYFGFSHSASGNPYDEQSLSFAFEGMGFDSRKTNSPTSHHNVPLTNGHYPSERVDGTLSQQHAPATRQCDSLGLQFSVQHAMQNNDVEHQEQSPRFPPQLGTFSRNPELHSFDRNFGVPCHPSIASASSLKMWQSQMYTPHDQNVGSNFMWQQNTGVQPYSIMQPNYACPQMQQVSGFGISRHRSNEQAAVYPPAKGPSSSYIGTPNFHWLENGYSYLNGAASQKRRNSGGLNNTFADSFPSTSYTGSSCGSGDFHHFQWAEKVFNSYGPHHQQGDNLSHPYGLGLSHHQRSDIAHPYGLGFSHHQRSDKLNTASYVERIRMRPDVGNSVNFFDLSSYARLLNSPFLSSQSDTYKSIDEVMGRVCMLSKDQDACRFLQKLLSEGTQEDIDKIFGEIIDNVGDLMVDPTAHYLVQKILEECTNDQRTHMIREITKAPIKLHKASCNVHGTRVVQKVIDTMNTPDQVSMLVSALNTGMMCLMTDSYGNHVVDHCLQKLLPEHKAFILEAAASCYLQLARDRHGCCVLQKCIGHSSDEQRNNLLCKITSSALTLSEDPYGNYVIQFILDLNIEWITVRVVDELAGHFGNLSMQKCGSHVVEHCLKLAPRLICDRIINELMHDPKLLDIILDQYGNFVIQTALKQCQGEHHAAFVETIKPHTAVMQSNMYGKKVLSRICLKNKHCRFDLH
The following text describes a protein:
Function:
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Miscellaneous:
MISCELLANEOUS: There are 2 genes for uS9 in S.pombe.
Subcellular Localization:
Cytoplasm.
Sequence:
MQSVQCFGKKGNATAVAHCKVGKGLIKVNGAPLSLVQPEILRMKVYEPILVAGADKFAGVDIRVRVSGGGHVSQIYAIRQAISKAIVAYYQKFVDEHSKAELKKALITYDRTLLVADPRRMEPKKFGGHGARARQQKSYR
The following text describes a protein:
Function:
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
Sequence:
MQILADLLNTIPAIDSTAMSRAQRHIDGLLKPVGSLGKLEVLAIQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAEQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYTQELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
The following text describes a protein:
Function:
May be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKAEATVIPSRCARGLPSWQVLSPVQPWQTSAPQNTTQPKLLAPHQHEKSQKKSSLLKELGAFHITIALLHLVFGGYLASIVKNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNSTVHIQRLELALLCFTVLELFLPVPTAVTAWRGDCPSAKNDDACLVPNTPLHLKGLPVEPPPSYQSVIQGDAQHKQHQRLREVKQVAPDTWIVTDGAAIWTQTAN
The following text describes a protein:
Function:
Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides. Active on paranitrophenyl-alpha-galactoside but not on raffinose, locust bean gum and gum guar.
Subcellular Localization:
Secreted.
Sequence:
MRALVPMVVAATALASPAPALKPRLDDGLARTPQMGWNTYNQYNCFPNESIVHENAQALVDTGLADLGYRYVTIDCGWGVEDRLPNGTITWNPELFPQGFPAMGQYLHDLGLLFGVYGDSGILLCGSPPNITGSLYYEDIDARTFAEWGADSLKYDNCYSDAATNYPNVNYAPSTSPHPRFANMSRYIQAQDRDILFQVCEWGIDFPALWAPEIGHSWRIGNDIIPHWRSIFRTLNQAVPQTDFAGPGQWPDLDMLLVGLDGVLTVPEEQTHFSLWSILKSPLTIGAAIPGMRAESLEILSNADVIAFNQDALGVSAALRRRWSDEGYEVWSGPLEGGRTIAAVINWRDEDREITLDLPDIGLQYAETLQNVWADETVNGVKTSYSSVVEAHGVMLVQLAETVEEGVYPADVFAATNRDVTTFSDVYAITSSPNFVLNITLTEVTAAATNITIITDSSRRPISTSIPAGSSSISTSVSLIAGSNNTITIRNAPPLSSITLSPPEPTYYTGAQDFTLTSPAGAYTCPDAYCLPAGSKIVDLSTESAATAHINSSTSGSKYLEIDYINNEVAFDSSWGWGANSRNLTIKVNDNNPVRLEVPLSGRHSELFGPGLGWWDSGRLGVLTDGWIKGTNELVLSNEGGEGGFTKYAPDVVGIAVYD
The following text describes a protein:
Function:
Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger.
Subcellular Localization:
Nucleus. Cytoplasm, Cytoplasmic ribonucleoprotein granule.
Domain:
PAZ domain provides a major contribution for nucleic acid recognition. PAZ binds oligonucleotides of different lengths and has a strong preference for single-stranded nucleic acids (ssRNA or SSDNA) or RNA duplexes with single-stranded 3' overhangs. Can bind the characteristic two-base 3' overhangs of siRNAs, indicating that it may contribute to the specific and productive incorporation of siRNAs and miRNAs into the RNAi pathway.
Sequence:
MGKKDKNKKGGQDSAAAPQPQQQQKQQQQRQQQPQQLQQPQQLQQPQQLQQPQQQQQQQPHQQQQQSSRQQPSTSSGGSRASGFQQGGQQQKSQDAEGWTAQKKQGKQQVQGWTKQGQQGGHQQGRQGQDGGYQQRPPGQQQGGHQQGRQGQEGGYQQRPPGQQQGGHQQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPPGQQQGGHQQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPPGQQQGGHQQGRQGQEGGYQQRPPGQQQGGHEQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPPGQQPNQTQSQGQYQSRGPPQQQQAAPLPLPPQPAGSIKRGTIGKPGQVGINYLDLDLSKMPSVAYHYDVKIMPERPKKFYRQAFEQFRVDQLGGAVLAYDGKASCYSVDKLPLNSQNPEVTVTDRNGRTLRYTIEIKETGDSTIDLKSLTTYMNDRIFDKPMRAMQCVEVVLASPCHNKAIRVGRSFFKMSDPNNRHELDDGYEALVGLYQAFMLGDRPFLNVDISHKSFPISMPMIEYLERFSLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFEHDGKKVTIASYFHSRNYPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQALNRKDGATQVANMIKYAATSTNVRKRKIMNLLQYFQHNLDPTISRFGIRIANDFIVVSTRVLSPPQVEYHSKRFTMVKNGSWRMDGMKFLEPKPKAHKCAVLYCDPRSGRKMNYTQLNDFGNLIISQGKAVNISLDSDVTYRPFTDDERSLDTIFADLKRSQHDLAIVIIPQFRISYDTIKQKAELQHGILTQCIKQFTVERKCNNQTIGNILLKINSKLNGINHKIKDDPRLPMMKNTMYIGADVTHPSPDQREIPSVVGVAASHDPYGASYNMQYRLQRGALEEIEDMFSITLEHLRVYKEYRNAYPDHIIYYRDGVSDGQFPKIKNEELRCIKQACDKVGCKPKICCVIVVKRHHTRFFPSGDVTTSNKFNNVDPGTVVDRTIVHPNEMQFFMVSHQAIQGTAKPTRYNVIENTGNLDIDLLQQLTYNLCHMFPRCNRSVSYPAPAYLAHLVAARGRVYLTGTNRFLDLKKEYAKRTIVPEFMKKNPMYFV
The following text describes a protein:
Function:
MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLILLGYLVVIGTVFGGYVMTGGHLGALYQPAELVIIGGAGIGAFIVGNNGKAIKGTMKAIPLLFRRSKYTKSMYMDLLALLYRLMAKSRQQGMFSLERDIENPKESEIFASYPRILADAVMLDFIVDYLRLIISGNMNTFEIEALMDEEIETHESEAEVPANSLAMVGDSLPAFGIVAAVMGVVHALASADRPAAELGALIAHAMVGTFLGILLAYGFISPLATVLRQKSAETTKMMQCVKITLLSNLNGYAPPIAVEFGRKTLYSSERPSFIELEEHVRAVRNPNQQQTTEEA
The following text describes a protein:
Function:
Probable transcription factor, which may be involved in embryonic patterning. May be required for basal embryo development after fertilization. Acts partially redundantly with STIP in promoting embryonic cell division and proliferation. Promotes cotyledon boundary formation by maintaining the symmetry in CUC genes expression domains.
Subcellular Localization:
Nucleus.
Sequence:
MSSSNKNWPSMFKSKPCNNNHHHQHEIDTPSYMHYSNCNLSSSFSSDRIPDPKPRWNPKPEQIRILESIFNSGTINPPREEIQRIRIRLQEYGQIGDANVFYWFQNRKSRAKHKLRVHHKSPKMSKKDKTVIPSTDADHCFGFVNQETGLYPVQNNELVVTEPAGFLFPVHNDPSAAQSAFGFGDFVVPVVTEEGMAFSTVNNGVNLETNENFDKIPAINLYGGDGNGGGNCFPPLTVPLTINQSQEKRDVGLSGGEDVGDNVYPVRMTVFINEMPIEVVSGLFNVKAAFGNDAVLINSFGQPILTDEFGVTYQPLQNGAIYYLI
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSGFRHLSGDRRRGKLPEKSNFAQTCNLLSQYIKDKGSLRDLNLEIGGKIESLENIVKQGSFCHEFTSKDAAAPTDSAAAGQLTIFYSGGVLVFDDYPAEKAEELVAFAANGGGSGILSNTSWAKPSSGGAAETSTPGESQLPPRPGSRKAAGVGITSNTASGGAAEVPPVENRGSTLPEANDSDLPIARRSSLHRFLGKRKDRAAARGPYQLQEQPASSSKGDEHFDLNL
The following text describes a protein:
Function:
Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60.
Subcellular Localization:
Nucleus.
Sequence:
MTISWRALSHFLIPQSDYGEAKTHLEQLQQTLTHLDHPHHHHAHHPHHHLGLYHGALPNTSTITTDSVVSCVSSTLPAVAKAISASSSCDGLQSERKKCPISDLDSGGHGHGQGHGLMEAICAGQKTSPIPPPPPPCCLTLGESSSSPNPIATAALMNASTSGSSSAGGASASLCNDLTRESSWYAHHHHHHHHHHHQLPDELVMYATPTPTPAIGKFGLDTSTEGYLNARYNVNVKGVRHDRTSSFFDIPAVTHPHNHPHPHPHPHPHPYCYRFPSSPPAGILKKSDEEATSAAVYCSDVSSGQHFPHHTKIEHADSTTTAAQQQQQQQEQQQQQQQQQQQQQHQQQLQQAAALHPHHHHSHHGHHGHQQAEQQALTHLTPLHAASAFKFSHTAVISSSAVYATPSHYAHQQQTQSQSVYRDLSPTTLAAVSDADLKYDSGPYNAAISSTYPSALRPNVVDSTTSSDAELRLDQFYASNGISTSSNGQAISQRRGSLQLWQFLVALLDEPTTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLRYYYEKGIMQKVNGERYVYRFVCDPDALFNMAYGHLTTGSGKGDQHQLTLSLAKTPPTSGDSQTQSPRVAKSEYYDTAALHKY
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSFVLNVSKSCTASVNQSDHIKPCFQSITMAPKVWRIKKTVIASDHQPTASDHKPTSDHNDKKEAGIKAVVAASGDSNNTEEQKEEPETAIDLGVSMDRLNLGSEKNKKKKLLVLPLRGILVYRAHRSRPETIPRNRRPDFCYGSFLVYKRPYCLGFLKFCFQRFNVGLWSSAREHNLQGILTNVMGNLKKKLLFTWDQEHGTDSGFKCLENRDKPLFFKELNHLWEKKYPNLPWSDGEYSASNTLLITDPEKSLLNPPNTAIFPRNYDPENRKDDFLGPKGELRVFLEGLAEAEDVQTYVEEHPIGDPEITPSHPDWDHYCKIICCVNKIRFGDPTPKLI
The following text describes a protein:
Function:
Has quercetin 2,3-dioxygenase activity in vitro. Its physiological role is unknown; however, may provide a mechanism that would avoid inhibition of key cellular proteins, such as DNA gyrase, by quercetin.
Miscellaneous:
MISCELLANEOUS: Quercetin is a flavonoid compound synthesized by a variety of plants, including foods for human consumption.
Domain:
Is composed of two structurally similar domains arranged face to face.
Sequence:
MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVINDDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMGNKEQVPAGEFQIMSAGTGIRHSEYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDMELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHADSDSEVLLFDLPPV
The following text describes a protein:
Function:
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Membrane; Single-pass type II membrane protein.
Sequence:
MAQEGVGYVNPNSSGPQGGSRLRRIGKSICNTEKGEFLGRTCSSWVKIGIFYTVFYACLAGFFALMLIGFFATLDERAPTQQRMYSLIKGNPGMGFRPMPNVESTLIKFSKEDNNTYQPYINNLNNFLKVYKAQNFSLEDCPKDFQKDLTICQVNMSMFGPCTEDNNYGYDEGLPCVLLKINRVYDWLPKPFSANETGLTGDEKNRFEQFISPIRKNIPLSSNHITVSCEGENEADEDNIINVEFYPPSGFPYRFYPYMNQPGYLSPIVFARFNVTQGALVQVWCKLWAKNIKHHKNDKAGSTHFELFVDK
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MIHICLIFSGLFLFWSTVFFLFSIYFIVEGLTWFLEFNLLMINSSSIVMTLLFDWMTFLFMSFVLFISSMVIFYSREYMASDIFINRFIMLVVMFVFSMMFLIVSPNLISILLGWDGLGLVSYCLVIYYQNVKSFNAGMLTALSNRIGDVALLMAIAWMVNYGSWNYVFYLFQLKGDSYMNVISYLVVLAALTKSAQIPFSSWLPAAMAAPTPVSSLVHSSTLVTAGVYLLIRFNFCFNEWLMYFLLFISSMTMFMSGLGASFEFDLKKIIALSTLSQLGLMMMILSLGSYELAFFHLLTHALFKALLFMCAGNIIHSVGDFQDIRYMGGLVKFLPLTCVNFNISNLSLCGLPFLSGFYSKDLVAEIMSMGYLSFYIYLIFYVSIGLTVCYSFRLVYYSFVGSFNFLSLNSVYEGSVMMIKGMGGLIFLVIFMGSSLSWIIFPYPYVIILPLFMKILTLLMVILGAWIGYELSKFFISYDSLSLKNYGLSWFLSNMWNMPVISTLGINYYPIIGGSFLYKSLDQGWSEVLGSQGIYSVIVSGSKISQIFMNNSIKIFFVLMIVWLMIIFMI
The following text describes a protein:
Function:
Binds directly to 16S ribosomal RNA.
Sequence:
MANTKSAKKRIRSDARKHLRNQSYRSRVKTMIKKAELALANGVVDEAALRMAYSTLDKAAVKGIIHKNNAARRKSRLAQKAKKVALAAQAGSAA
The following text describes a protein:
Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein.
Sequence:
MSTEAQRVDDSPSTSGGSSDGDQRESVQQEPDREQVQPKKKEGKISSKTAAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQWTKRYAT
The following text describes a protein:
Function:
Mediates the transport of UDP-N-acetylglucosamine (UDP-GlcNAc) across the Golgi apparatus membrane. Delivers an essential substrate for the maturation of N-glycans and the GlcNAc-containing glycosyl inositol phosphorylceramide (GIPC) class of sphingolipids in the Golgi apparatus.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MRNNPVLPVSDPPLAGENDSDGKGVDDRLFKGSAMTKRGAYAALSYMACAVMLVLFNKAALSSYDFPCVNVITLFQMVSSSLFLYALRRRKIISFTAADSFSIDSASTFVPVKTLFHTLPLAIAYLLYMLASMASVRGVNVPMYTTLRRTTVAFTMVIEYMLTGQRYTRSIIGSVGIILLGAFFAGARDLSFDFYGYGVVFLANISTAVYLATIARTGKSSGLNSFGLMWSNGIICGPILMIWTFICGDLEKTINFPHLLTPGFMVVLLCSCVLAFVLNYCIFLNTTLNSALTQTICGNMKDLFTVGLGWMLFGGLPFDLMNVIGQLFGFFGSGLYAYYKIIGR
The following text describes a protein:
Function:
Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Sequence:
MLTMFSGSKIAEMPPTSSQLRPPHLRNRGTSTSSVPTTNSGTINTADAQERRRLEHHEADVVIVGAGIVGCAAAVAFGKQGRSVLLLEKSLKEPDRIVGELLQPGGVNALEKLGMKDCLDDIDAIPCYGYQVSYHREPTPSKPARGAAPSTMARFISKLRAKARATPNVTVVETTVTDIVKSEYNNQVLGAVTLVADGYASKFRKEYIAQQPEVRSKFWGLELIDAELPMPNHGHVILTDAPPILIYQIGTHETRILVDIPDGLPSASVKAGGVKNHMLNVALPNLPECVQPSFRRAIEAGKLRSMPNSFLPPQTQKTPGLIILGDAMNMRHPLTGGGMTVGFNDVVTLSTLLSPANVPSLEDTSAVLSAMSQFHWARKSGSSVINILAMALYSLFAANTPQVEALKNGCFRYFQLGGKHISEPAGLLSGLIKNPLVLVYHFFSVAFYAVWCRLKEESVWKAPYVLTVESAMIVWTAACVIGPYLVWEVRR
The following text describes a protein:
Function:
Glutathione-dependent oxidoreductase with lower activity compared to the other members of the glutaredoxin family. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase.
Miscellaneous:
MISCELLANEOUS: Present with 573 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MSAFVTKAEEMIKSHPYFQLSASWCPDCVYANSIWNKLNVQDKVFVFDIGSLPRNEQEKWRIAFQKVVGSRNLPTIVVNGKFWGTESQLHRFEAKGTLEEELTKIGLLP
The following text describes a protein:
Function:
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MQSMKKVIGSIEFGILSPQEIRKMSAAEITVPDTYDDDGYPIEGGLMDKRLGVIDPGLRCETCGARAGECPGHFGHIELARPVIHVGFAKTIHRVLESTCRECGRIKLTDEEIEEYMQKFEVMGDRKGAVDKLIKEIHKKAKERMVCPHCGAPQFPIKFERPTIYWELRKDEEGNEYKHRMMPSEVRDRLEKIPDKDLPLLGLHPEKSRPEWMVLTVLPVPPVTMRPSITLESGIRAEDDLTHKLVDIIRINNRLKSNIEAGAPQLIIEDLWDLLQYHVTTYINNETSGVPPAKHKSGRPLKTLAQRLKGKEGRFRGNLSGKRVNFSARTVISPDPMISINEVGVPLAVAMELTVPEKVTEFNYEKLKQRVLNGPEKYPGANYVIDPEGRRIRLMESNRELIAEKLDIGWTVERHLEDGDVVLFNRQPSLHRMSIMAHRVRVMPYRTFRLNLPVCPPYNADFDGDEMNLHVPQTEEAQAEAKILMEVQNHIISPRYGGPLIAGIQDHISGGYLLTREGAYFTRYEVEQMLMFAGMDVNELPEPDKYENGEPLWSGKTIFSLLLPDDLTIWYRNKLCDEPERCEALEKLIEEKLIPDPEEVRKLAYDGFVYIQNGKLLSGAVDKKAYGREDGKLLDIIVREYGVERARQFLDQVTKLTIWVITHKGFTTAIDDEDLPQEAIDRIHEIIREAEEKVQRLIEAYKRGELEPLPGKTLEETLESKIMAVLAEARDNAGKVAERYLGMNNHAVIMAKTGARGKILNITQMAAMLGQQSIRGKRLYRGYRGRVLTHFKPGDLGARARGFVTNSYKSGLTPQEYFFHAMGGREGLVDTAVRTAQSGYMQRRLINALQDLKVDYDGTVRDPTGIIVQFKYGEDGVDPMKSWQGKTVDVDRVIVRTLLKMRGGGE