lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Lectin specific for terminal, non-reducing N-acetylgalactosamine (Gal-NAc)-containing carbohydrates including N,N'-diacetyllactosediamine/LDN (GalNAcbeta1-4GlcNAc, LacdiNAc). Specific also for carbohydrates containing N-acetylglucosamine (-GlcNAc) or N-acetyllactosamine (-Galbeta1-4GlcNAc) at the reducing end. Agglutinates human blood group A, AB, B and O erythrocytes with a strong preference for group A. Agglutinates bovine erythrocytes with a very low specificity. Binds carbohydrates bivalently, which is required for its biological activity. Exhibits insecticidal activity against the fruit fly D.melanogaster, mosquito A.aegypti, and amoebozoa A.castellanii. Has anti-nutritional activity against Colorado potato beetle L.decemlineata, and against worm C.elegans. Has antiproliferative activity against human leukemic T-cells. Has an immunostimulatory effect on human antigen-presenting dendritic cells, which are subsequently able to induce efficient T-cell immune responses.
Domain:
Contains a single ricin B lectin domain with a characteristic beta-trefoil fold consisting of three repeated subdomains each containing a more or less conserved QXW motif.
Sequence:
MSITPGTYNITNVAYTNRLIDLTGSNPAENTLIIGHHLNKTPSGYGNQQWTLVQLPHTTIYTMQAVNPQSYVRVRDDNLVDGAALVGSQQPTPVSIESAGNSGQFRIKIPNLGLALTLPSDANSTPIVLGEVDETSTNQLWAFESVSAV
The following text describes a protein:
Function:
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA); A component of Cascade, which participates in CRISPR interference, the third stage of CRISPR immunity. Cascade binds both crRNA and in a sequence-specific manner negatively supercoiled dsDNA target. This leads to the formation of an R-loop in which the crRNA binds the target DNA, displacing the noncomplementary strand. Cas3 is recruited to Cascade, nicks target DNA and then unwinds and cleaves the target, leading to DNA degradation and invader neutralization. CasCDE alone is also able to form R-loops.
Sequence:
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSVDEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQLKSWVRNNGEA
The following text describes a protein:
Function:
Catalyzes the conversion of maltooligosaccharide into the non-reducing saccharide, maltooligosyl trehalose (alpha-maltooligosyl alpha-D-glucoside) by intramolecular transglycosylation.
Sequence:
MAFPVISTYRVQMRGRSNGFGFTFADAENLLDYLDDLGVSHLYLSPILTAVGGSTHGYDVTDPTTVSPELGGSDGLARLSAAARSRGMGLIVDIVPSHVGVGKPEQNAWWWDVLKFGRSSAYAEFFDIDWELGDGRIILPLLGSDSDVANLRVDGDLLRLGDLALPVAPGSGDGTGPAVHDRQHYRLVGWRHGLCGYRRFFSITSLAGLRQEDRAVFDASHAEVARWFTEGLVDGVRVDHLDGLSDPSGYLAQLRELLGPNAWIVVEKILAVDEALEPTLPVDGSTGYDVLREIGGVLVDPQGESPLTALVESAGVDYQEMPAMLADLKVHAAVHTLASELRRLRRCIAAAAGADHPLLPAAVAALLRHIGRYRCDYPGQAAVLPCALAETHSTTPQLAPGLQLIAAAVARGGEPAVRLQQLCGAVSAKAVEDCMFYRDARLVSLNEVGGEPRRFGVGAAEFHHRAATRARLWPRSMTTLSTHDTKRGEDVRARIGVLSQVPWLWAKFIGHAQAIAPAPDAVTGQFLWQNVFGVWPVSGEVSAALRGRLHTYAEKAIREAAWHTSWHNPNRAFEDDVHGWLDLVLDGPLASELTGLVAHLNSHAESDALAAKLLALTVPGVPDVYQGSELWDDSLVDPDNRRPVDYGTRRVALKALQHPKIRVLAAALRLRRTHPESFLGGAYHPVFAAGPAADHVVAFRRGDDILVAVTRWTVRLQQTGWDHTVLPLPDGSWTDALTGFTASGHTPAVELFADLPVVLLVRDNA
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Sequence:
MAPPTNLVKISASQCAPSSLYTTLLLTSCALCPAFAPPQLPWFFPLSNTSSPPHPPLVGLFASKAEQGTSVDRVQAIAASSALLGTSSRRASQPAESPEPAPRPQGLHSPVVLFLCVFAVYTFLSLFSLSNLSLTNFDSHSLYSLYSLYSLYSLYSLYSLYSLYSLYSLSISLCSLYSLSISLCSLGSLSNQFISLPSISLSLCLCCLCLSLSLTSRSLSLSLSLYALSLSLRFLSLSRSLFTLSLSLYALSLYALSLYSLSLYALSLSLFLDALSLLTHSLSLSLYALSLFTLSLSLRSLSLSLSLSLSLSLLHFLDVDLLINAHVTRASRALSLSLSRETAAAGDPTRRPELLKHHFYNLTFVDLFAVVYAGFILEVQEVMSIGSDAFRDRVAALTVDELQKQLEKPKQDTCAADDGFEVLNVPAPEEAPKNRAPTTKSCHSCHEQLEIIGGHHTCRSCNASLCQGCTRYIQLDRAFAEQLENDVGIPFFTRYFTYARRAIFEKTTRVKKTPICDRCKSILDQGPRAEEQVLEAATTFRLALLPLEDLIFLQEVDSTWRQAAEQCIQQLLTVNYRLLSAHGPEDFSCEERQLLMRNRFYLRGHPEWMATLLRAFANCTARQEKTLLDLINMTPEEAMTQITGHFGQSPSNVTCDHLGCQERCHDLMSDYGQLLPPTMALTLLSPLVGMTSPTFRHYCLESLKSFWNAEMGRHILTQLEAILMVRGNADEFPPIWALLLDWAEELESFRTDLYWLLQCMLGEPRNTSRALRMLLDLCGKMSCVYSPNYGHLSTENMTRPLTWAANVREVTRAGLVYGAGAAGSGSIARMRQKINEQLQDGLYTVPIPLPYDPNQLLGAIHADDILCPGGVKGMVRFKFDVEPNHVVLSTPSSRCTTATTRSPASRPWLDDRPIPVFSLADASPGMRGAAVHRPVATSRLDLEDEEDPTSMVHSFIARSANELQKTLEDVNAKQQIRQDRLKAEMTASLLEAIEDGGSDSGSDFEDCNLEDLVENTVSTTPVACPRGSRDATPTGEAECNNAPTPSKSSPAPTTPHLIEGKDGTASEVPASNLRAVSEPEHRPGSSLPSHPQPPVTPPVPLLLERSAVSYSSPASLESRSWRDRADSRTSQGSLFSRADSDVRLNEDRSTCFLAYKPDDVRIDDTVMRTIRLVVELLRTDKRFDVKDFDDDDIVTYGVTPTSSEDGFVEWIDNAKTLGSLMAEDQGYAFHTFRHHDPNTAVGLLKRRLWNSLAVYAALTYILGLGDRHGDNILMTRTGKVFHVDFGYVLGADPKPWLRLSVAVTKKLLCATGGAEVQQEFLELAGDVYVAIRRHRHVIMAQMLALTLKQPTINSLPTATLIDRHFAERLMPYASETEARDKYLQIFRNETESASAQLPAMAARTTPALAARFGALAQTPARVAVPAFVRAYGGGAAVPTQKELEERFQSIFRLYDKIDESKLTAQAHFVNDLGLDSLDVVEVISVFEEDLSYDLPDTEALNIFSIEDAAKAFLKHM
The following text describes a protein:
Function:
Does not have a catalytic activity.
Sequence:
MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFMKVSESSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETASFITYDGSMTIPPCYETASWILMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNEWLLK
The following text describes a protein:
Function:
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).
Sequence:
MYWKLLFGKEMLENVWRSILVDMNKKVKLDNKAFNSPLVSLSDEGFCRLLDFAKGDRPLVVNFGSSTCPIFMKKMLEYEKMIVQFKDVADFVIVYIEEAHPSDGWAFDEDHIGVIGIDITLSELLKNAEVRAIMGIDWKMKIIDEIVTGSGAICQKSS
The following text describes a protein:
Function:
Transcription factor (By similarity). Appears to be indispensable for the central nervous system development. May have a role in the neuronal differentiation of the ganglionic eminence and ventral thalamus. May also be involved in axonal guidance in the floor plate.
Subcellular Localization:
Nucleus.
Sequence:
MSSQYDDDSRDRSECKSKSPTVLSSYCIDSILGRRSPCKVRQLGAQSLPAPVRPDHEMTTEVTSKENSFDSDMHLPPKLRRLYGPGGKYLDSGRGFHEHLEKGERERLLDQACESLKISQAPQVSISRSKSYRENAPFSQSDEGQSPEHMAQELVELSTLKFEEDVVKEEACGDNSLSPKDEESLHNDGDVKDGEDSVCLSAGSDSEEGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGVQAHPTGLPFPGPLAAAHPLSHYLEGGPFPPHPHPALESAWTAAAAAAAAFPGLAPPPNSSALPPATPLGLGTFLGTAMFRHPAFIGPTFGRLFSSMGPLTSASTAAALLRQTAPPVESPVQPSAALPEPPSSSSSTAADRRASSIAALRLKAKEHSAQLTQLNILPSGTAGKEVC
The following text describes a protein:
Function:
Has bacteriocidal activity against both aerobic and anaerobic Gram-positive bacteria. Inhibits growth of B.subtilis (MIC=0.047 ug/ml) and methicillin-resistant S.aureus (MRSA) (MIC=0.047 ug/ml). Has poor activity against Gram-negative bacteria, with the exception of B.fragilis. Inhibits bacterial protein biosynthesis by acting on elongation factor Tu (EF-Tu). Full antibiotic activity depends on the presence of the modified residue Ile-50.
Subcellular Localization:
Secreted.
Sequence:
MGNNEEYFIDVNDLSIDVFDVVEQGGAVTALTADHGMPEVGASTNCFCYICCSCSSN
The following text describes a protein:
Function:
Does not exhibit any ribonuclease activity.
Subcellular Localization:
Secreted.
Sequence:
MASDAASLLVLQLVLQPTLVTGITIQTAIKNFRILHVDYPMVNYPKGFHGYCNGLMAYVRGKLQDWYCPKIHYVVHAPFESIQKFCKYSESFCEDYNEYCTLTQNSFPITVCTLDHKQAPTSCSYNSTLTNQRLYLLCSRKHDAEPIGVIGLY
The following text describes a protein:
Function:
Transcription repressor that binds to the promoter of gapB and pckA genes, preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes.
Sequence:
MSTIELNKRQEHILQIVKENGPITGEHIAEKLNLTRATLRPDLAILTMSGFLEARPRVGYFYTGKTGTQLLADKLKKLQVKDFQSIPVVIHENVSVYDAICTMFLEDVGTLFVVDRDAVLVGVLSRKDLLRASIGQQELTSVPVHIIMTRMPNITVCRREDYVMDIAKHLIEKQIDALPVIKDTDKGFEVIGRVTKTNMTKILVSLSENEIL
The following text describes a protein:
Function:
Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
Subcellular Localization:
Nucleus.
Sequence:
MKLRSQRALTERCRPAGRAAGGGAGGTAAPDGSRAAPRDLPVRDGGEGGARSSQQRHGTAVRCERPSARGGKAERCATKAEAGGRARRSSARSDAGSERGKRRRAARGDREAAGVQNEAPCEEAARVRHGQAVAELRAPPAAAGTQCVPAGQRPEPQPGAAADRLQGRPQSAAGGGERTGAGTAPAVLGEEESSGWKTGEETEPGDPGTRDSAADGDVSWPSDKKSFTAVQAPRGTEESAPRTQVDRRKTSPYFSSKYSKEALSPPRRKAFRKWTPPRSPFNLVQETLFHDPWKLLIATIFLNKTSGKMAIPVLWEFLRKYPSPEVARTADWKEMSELLRPLGLYALRAKTIIKFSDEYLNKQWKYPIELHGIGKYGNDSYRIFCVNEWKEVQPQDHKLNIYHAWLWENHEKLSVD
The following text describes a protein:
Function:
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
Sequence:
MSAAASPRSLTLIGAGLAGCLLAILLSRRGWQITLYERRGDPRIKGYESGRSINLALAERGRHALRQAGAEDAVMAKAVMMRGRMIHPVSGEPQLQRYGRDDSEVIWSIHRAALNVTLLDLAEQAGARVHFYRRLHTVDFDAGYARFIDDRDDQPHEIHFQALVGSDGAGSALRAAMQRKAPVGEHIAFLDHSYKELEIPPRADGGFRIERNALHIWPRGRYMCIALPNDGGTFTVTLFLPNEGMPSFATTRSGDEALALFARDFPDALPLIPQLKEHWEEHPPGLLGTLTRERWHLDGRAVLLGDAAHAMVPFHGQGMNCAFEDCVALAEQLDAHSDLSEAFAAFEAARRDDAAAIQQMALENYLEMRDRVGDAQFLLQRALEQQLQARWPTRFVPHYTMVTFLRTRYAIALARSEIQREILLEATHGHTDLSRIDWVALETVVHARLEPLEGAH
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. Also catalyzes pseudouridylation of mRNAs with the consensus sequence 5'-GGUUCRA-3'.
Miscellaneous:
MISCELLANEOUS: Present with 3990 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Mitochondrion.
Sequence:
MNGIFAIEKPSGITSNQFMLKLQHALTKSQVFSKEIQRATAERKQQYEKQTGKKASKRKLRKVSKVKMGHGGTLDPLASGVLVIGIGAGTKKLANYLSGTVKVYESEALFGVSTTSGDVEGEILSQNSVKHLNFDDLKTVEEKFVGQLKQTPPIYAALKMDGKPLHEYAREGKPLPRAIEPRQVTIYDLKVFSDSLKRDHDYPLLRPTTEEAVDTVKNLNANMLNDVLYFSKEYTEKHGLDSEVAKVEEPFPLSEQEEQEIQKEGDSYRAPKLHFKANVSSGTYIRSLVSDIGKSMRSSCYMVKLIRLQQQDWSLEKNNVFQLTDFTERDEKVWSKVLEKVLDEGATVDVIEELKKAEKEIPADVKECIVSSDQPGDEATAETIETANAEEHSNTLKRKIEQV
The following text describes a protein:
Function:
Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MKPGEAIKIRRAHVAKLTYGARLCRGPYYCAFISKAGFNIITGNSWLTILGCTNMDLLLIVALLLMQMGIWSRAEKDFSSVTLPGLQATSDYVTQCFDKSHGAVVCDWTKSQKSALTGAMVNILESPLLGIEGKACLEFWFLVPVAATGSEVTVQLKSNSSLEKIWVSPVLRRNAWRQILLNLNVTEQDTQVLFEAIQPVALQDQTTLRQIGVKKGSCGNQCDSDTDFWPDDATRCLCSVGMLLCFPSNCPKDQICGSNKFSTSGICTIRDHTEYSTFDGVQFQSMAPCSYVLTKSCTEVMEKFSVEVVNEQGGNSSITMVKGITMTLGNIMVSLIEKQRDKVVVNGVWKSLPFSINTSIDVQIQSNSAATLLEAGFGLSVSYDHAGAISVILPSNFSNEVCGLCGNFNHIHRDDFLMANGTMAENVTALAESWQTETTSTSCKSALVSPKCDPLDEEEYASEMYCGLLLSGSGPFANCTSVVKVESYFKACVSDMCSAHGDQAELCKTLQLYASVCQDAGAALPMWRNSMFCPLMCGNNSHYNACADGCPKACFSQNKTSCGSCEQRCECDAGFKLGRNKCITAEDCGCLYDGKYYEKGEQFVRDDCIQQCQCMGNDLLECTKLQCSNNKVCKEMDGVRGCFPFKPATCSVYGDLHYITFDNLAYNFQGGCSYILTTSCGDAQSLNFTVIGHNMHPPLQNVTRSKLNSASLEVDDLRCTLTQSGEVYVHENLIRLPHSVSGTYGAVWIYAEENYIILKASFGLKVILDGQGRLFLQVDEQYKYNLCGLCGTYSGFQGDDYYMPGEHVANETSEFGNSWRVQNECITEETYPRQCDSETIANMECSMLFKDEFSACQEHVHPSIYLNSCVYDYCATSGDQHTLCDSLKSYESACQIAGVTLPNWEPGTACAQRLLPTSTPSPSSPEQTFCPMDCNFDENLCGWEQVIKDSCDWTRYSGPTPSNLTGPNQDHTSGDGFYLHLESNGVSHGNSASLQSSLCSYSGPLCLHFWYYLYGSAVGMTLNIFLLKDNKAVKLWSVVNNQGPKWHLASVDLRVSGSFQIIIEGVRGASDQSDVALDDISTSLGTCSEVVSRFTDETVQTTEIIPSPVCSVNCSFDGSLCSWNKMATDALDWIWNSYTPTPISDSTSGPTNGGSYLCIEAKGMVQGNTARLISPECSAIGPHCLQFWYHMHGPSDHMGLDVYLLQNQATEIVWWKRHDQGNVWHLALVDFYATTMFQILIKGQRESNDQSVVAIDEMKLLHLPCSDVRMANEVLPSRYFNPADLQSAPPQTLSPINKSPTKEVITQPADGCQMNCNFEEDLCQWTQQLDVFDWKRHSGPTQSTISASSNSKQGGHYIYIEAKSVPFGETARLISSECSAAGPHCLQFWYLMDDSAGEVGLDVYLLNDGNTDSLWRKREGQGIVWNLAQVNFVTTGTFQVIFEGRGSDQSVAIDDISLHRGFCAGSGPSQGSIAGIPKMATSKTLQNSAVMLGTSKTATHQYQLQQTQLQVTPRPQVAQRQPPTSRCNETTVPHQPATEPKYRPETTVKQPLTTKGNATIAQQQLSTPTPESTPKTNVLKNQTYHSNVTAAPQAPSTAAPEVATRTVTTGGNPLQPTTATPESTPHISVKQPLTNRSNTPAGPQLPSTAAPEVSTRTVPQTVTTGDNPTAIPLQPTTAMPESTPHISVKQPLTNRSNTPAGPQLPSTAAPEVSTRTVPQTVTTGDNPTAIPLQPTTAMPESTPHISVKQPLTNRSNTPAGPQFPSTAAPEVSTRTVPQTVTTGDNPTAIPLQPTTAMPESTPHISVKQPLTNRSNTPAGPQFPSTAAPEATNLPKITAGKLTVTTGNNATMGPQQLTTSASGSTIGTLPQTTARPKSVFTKGSATENSNIHTTSTPDSSTVMGTTASPKLLNPTATRPEFTTATQLKNATVPQPLPTQGNGMVTTQHPVVLKSTIGTKSPTSSKSQTTEASQQFTTAKPKSTVGTQPQTRSGPQSATAAPQLSTAKPESTSVQSPFTGKLQPGTTRPQTATTVPQFSMTKPQSTTSPLITEPKPVTAKSNTVSQEHTAIPAQTFSTETTTRPQLPVVHSNETTPQLHSTTPAAAVFKPVTAKVNETVTPHLPANTTPKPQLQTMFRPQSKTTQQISKAPTCAKNSHYTTCIPPCNPTCTHLNGSPGCKEKKCTSGCVCNDGFVQNERSCVPVQKCGCQDTNGFRHNFNEVWYTNHCSQKCECEEEDGTGKVVCDDEECEDAVCLPNEMGYFCQSTGFSECTIQGDPEYRTFDGMKHGFEGKRSYVLVRTKNLPKNIPQIYIEMINACTIDSQSDEDDGSEEDSSSDDDSELQKMQQVKIQVYNHTVELKKNRQILVDGNGAKTPVSPTSGLTIQERSSRVYLKTDFGLSVEFNGHCKTEIILPTIYRKKVEGLCGNFDGRKWNDKVKPDGSTAKSIDEFGESWRVSDLG
The following text describes a protein:
Function:
Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
KKRAMPCLCDSEIQDAKKNNQTLIIHNEKVYDVTKFVNVHPGGSKILSLRHGKDVTNIMANAPHVHSKNAYRWLQQYYVADYKPENSTSLNGLNGPEIRDRKLSYNGKQNASPASNQLYEIKPTEDLINWNEPVLWQVGHLREKYHDWVDDPVDRSLRLFKSDFCEFFSKTPWYIIPLVWLPIVALFVLRSHTEFLAGKAMILHSLPGPYKIFFFQVFVSGILLWTFLEYGLHRWLFHSEPPKTSYFLITLHFLLHGQHHKVPFDSGRLVFPPVPASMLFLIAYSVFRLCFVVGVADIVSAGVILGYVGYDMTHYYLHYGQPKRGSYFDRLRAYHVRHHFESPNLGFGISSKLWDYPFQTTIKTNKEKNF
The following text describes a protein:
Function:
Cell surface proteoglycan.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MRVLLLCGALLVALVGTCSGEVNDEIYIDDATEGSPDMLAEIEMSSGDGPNGVVGPTTDDEDLVEGSGTSNNLEDPDVSFSPTTRLTTINNNIQENVGKDQSTISNNLGGMYDQENEVRYKNDNDALNGGPNDVNEEPQNFFKMIFENPAILAGMVGAVVLILLTVVLLFLFVIYRIKKKDEGSYSLDEPHKVKDPTAYWKDTKEFYA
The following text describes a protein:
Function:
GTPase-activating protein for the ADP ribosylation factor family.
Sequence:
MSDENGPSKVDLQTAMRKMRALPPNKLCFDCGARNPTWCTVTYGVFLCIDCSAVHRNLGVHLTFVRSTNLDTNWTWLQLRAMQLGGNGNANQFFKAHGCNTTEAQQKYKSRAAQMYRDKLSTLCQEAQRKFGTQLIIDTVTHAEEKPAEEEDFFAQDFGHTSASATSLSSDAYIADHKSEDSTHGPSVDHLDSSVAVPTSAPVSVILKKPIKKATLGAKKNALGAQKVRINFDEIEQRAAEKERQTAAEVAANKLAYQTELDGKKKSDDAAALQKLSAKFAMQDIDAQRKQMEAKVAKDPTKAASVDRLGMGGVGRSRAAHSVAGGIRSIKQDDVLTFKKPSQPKEDDDWEVIDDKYGKKSTNNEDDFFSKDYTSSSSKKTTKEDDFFDSFETQPVQKSRYTASSSSSSTSRAPTTRLTAGASPISDVDLQKKFGNAKAISSDMYFGTPEMDCETRSALTKCEGQTSFGSEDLWGNGSQQRQSSQVPDMSDLKDSFRAGASKVAEKWSTLSSSFSTYMSRAPPATGEKT
The following text describes a protein:
Function:
Involved in calcium homeostasis, growth and proliferation.
Subcellular Localization:
Cytoplasm, perinuclear region. Endoplasmic reticulum.
Sequence:
MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQTPELEPAATMPPLPQPPLAPAAPIPPAQGAPSMDELIQQSQWNLQQQEQHLLALRQEQVTAAVAHAVEQQMQKLLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDECK
The following text describes a protein:
Function:
Specifically methylates the N1 position of guanosine-37 in various tRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MPLCLKINKKHGEQTRRILIENNLLNKDYKITSEGNYLYLPIKDVDEDILKSILNIEFELVDKELEEKKIIKKPSFREIISKKYRKEIDEGLISLSYDVVGDLVILQISDEVDEKIRKEIGELAYKLIPCKGVFRRKSEVKGEFRVRELEHLAGENRTLTIHKENGYRLWVDIAKVYFSPRLGGERARIMKKVSLNDVVVDMFAGVGPFSIACKNAKKIYAIDINPHAIELLKKNIKLNKLEHKIIPILSDVREVDVKGNRVIMNLPKFAHKFIDKALDIVEEGGVIHYYTIGKDFDKAIKLFEKKCDCEVLEKRIVKSYAPREYILALDFKINKK
The following text describes a protein:
Function:
Master transcriptional regulator of the switch between 2 heritable states, the white and opaque states. These 2 cell types differ in many characteristics, including cell structure, mating competence, and virulence. Each state is heritable for many generations, and switching between states occurs stochastically, at low frequency. WOR1 Binds the intergenic regions upstream of the genes encoding three additional transcriptional regulators of white-opaque switching, CZF1, EFG1, and WOR2. Phenotypic switching from the white to the opaque phase is a necessary step for mating. Plays a role in cell adhesion and pseudohyphal growth.
Subcellular Localization:
Nucleus.
Sequence:
MSNSSIVPTYNGYIHNTRDALAVIQQVLDKQLEPVSRRPHERERGVLIVSGSVFVFIEQSSGIKRWTDGISWSPSRIQGRFLVYGELDKKNLIDKDKKKKKKRKFGPDDEYDHNVNEPDYTGGYGNHLHNDNRSHLNKNSRSGPMLLATGTGSITHTVIENKPSSSASMIHSNVIPASSSFLTDYRTSLGNGPMVSAAISQNGLVKKTITLTTTTKELHMEGKAEKQTIHLISYYSKQDIDSGKLQRPSESDLKHVQISPALWTMVQENSLGGKAPIDDEECFIVDGHNQYTNVSYIQQQQQQHQLQHQPLLHHSSSVAGSTTSIVNNSLSISNGGYGNNYSKNLSRSYNKYSNSQVSQLSYMLPPQTESSSTATIASGASVSVKREDDTNNGSNAPTGNENQYVNAINHSHTSSYGGQGYATDATGIATPAYNSYSQANTSINTSSQQQQQLQQGQYGQYVQYGVAPSTISGATSTNNNSGNAPNIPQDVYYSHYTGFVQPHYPQYHIATGNASDQYNTNAANHQYHSNNTTSSANNNSSSRTTGVGSKRKPSIVSNSTSGSVSGGNGNGNNYGYNSNSSTSTNRPPAVSTNTTSTTSGGSSFSGPSSNITTNSMSNNPWFNSSTNMAVNSSYITSSGGGNSHGGIGNNEYEPMPMTNNSASIPAYYQQHVPSHVGSAQQHQSQQQVAGVGAPHIIHNHPYLHPTYGQGSNSASTGDNSTPGGSSGSGSGGSGNNGAGGSSSVAATSGVTSSNTSGNIVTNGTLVAAGTDDAVGNSSGSYYTGT
The following text describes a protein:
Function:
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein.
Sequence:
MIKKILTTCFGLVFGFCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRQELYEKYGEDAYTQGFKVYTTVRADHQKVATEALRKALRNFDRGSSYRGAENYIDLSKSEDVEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVTLDRRALGFAARAVNNEKMGEDRIRRGAVIRVKNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRSSELPASLSMALGTGETTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRVGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGVVSSNGEYYMKERMVTDPGLTLDNSGIAPQPSRRAKEDDGGAAEGGRQAADDEVRQDMQETPVLPSNTGSKQQQLDSLF
The following text describes a protein:
Function:
Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side (By similarity).
Subcellular Localization:
Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Note=Cycles between the endoplasmic reticulum and Golgi via COPI and COPII dependent pathways.
Domain:
The cytoplasmic C-terminal domain contains an Arg-Val motif, which is involved in the anterograde ER-to-Golgi transport of the protein.
Sequence:
MERRQAKIHVFVLIGLILLNSINQISSLSVTVNDEECVQEYVLYEGDTVSGNFVVVDHDIFWGSDHPGLDFTVTSPAGNIVQTLKGTSGDKFEFKAPKSGMYKFCFHNPYSTPETVSFYIHVGHIPNEHDLAKDEHLDPVNVKIAELREALESVVAEQKYLKARDTRHRHTNESTRKRVIFYTVGEYIFLAAASGLQVLYIRKLFSKSVAYNRV
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MAAPDHLFTLRNNFYLGAYQAAINSSDIPNLSPDDVVERDCIVYRSYIALGSYQLVINEIDDSAPTPLQAVKLLALYLSSPLNKESTISSLKGWLADSTYANNATLRLIAGTIFMHEEDYNEALKHTNAGGTMELHALNVQIFLKMHRSDFAEKQLRHMQQIDEDHTLTQLAMAWLNLAVGGAKVKEANLIFQDFSEKYPMTNLILNGKAVCFMHMANFDDAETLLLEALNKDAKDPETLANLIVCSLHLGKPSSRYLSQLKLSHPDHMLVRRSSSAEENFERAVQSVA
The following text describes a protein:
Function:
Structural component of the gap junctions.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Sequence:
MVLAAVLSMLRYVGGSDDRDFVDRLHSYFTCNLLIGLAVLVSFKQFGGKPVECLVPDIFSSSWEQYAENYCWASDTYYVPTNEPVAGLQSDEKRQRKISYYQWVPFFLLLEAACFRLPSLLWKYLAGHSGIKINEIVKLSSDPNNIKPDIKRANIKSLTVHLQGALRFHRRLQKKQIRPHRFLWLFNLPYSAFFVTAMYLCTKFFYLANVCLQLMFMNRFLETDKYKWYGMGALVDLLNGTTWEQSGMFPRVSLCDFDVRVMGNMQEHTIQCVLVINIFNEKIFILLWFWYLALLVFTFGSFFYWLLVSLWRHLNVRFIIRHLEMSDIAFDSSEDGAQEKVNRFISNYLKSDGVFVIRMMTLQSGVIFGTDLVQELWRNFHGSEPQLKRSNSAPKIEEREQWWPAYPSLVNPINPWRYRDENQANALRWRRALGANVDNSIATQDLMEKLLPQNAHMRPSDDELLNRQPIAVQASYIDDESDGKLKNEEKQNQQNATQPPYCYTNQNPTPYQNQNQIQNQNQYSNYYRTPSLSRGTDSRPVSTATDTDQTKKQSMSTFK
The following text describes a protein:
Function:
Binds to the 23S rRNA.
Sequence:
MQVILLDKIVHLGQVGDQVNVKSGFARNFLIPQGKAVMATKANIEHFEARRAELEATAAANLAAAQARAAEVTALGSVTIASKAGDEGRLFGAITTRDVAEAVTAAGVKIAKSEVRLPNGPIRTLGDHDVRFQLHGEVFAALDVIVVAE
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42 (RPL42A and RPL42B) at 'Lys-40'.
Miscellaneous:
MISCELLANEOUS: Present with 7880 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSVTFKDDVHRILKFVANCNGRFEDSKCDIRESPLGGLGVFAKTDIAEGESILTLNKSSIFSASNSSIANLLCDSSIDGMLALNIAFIYETTVFRNSSHWYPFLRTIRIRDDEGHLNLPPSFWHADAKRLLKGTSFDTLFDSLAPEEEIMEGFEIAVDLAHKWNDEFGLEIPKGFLDVSEENHEEDYNLKLEKFISVAYTLSSRGFEIDAYHETALVPIADLFNHHVSDPDLKFVSLYDVCDKCGEPDMCKHLIAEEYLEAENLDKNMPKVASMETRVIDEDLIKSLENDLEKEYSNVTANIEDDDGGIENPDECVDLVLKNDVAQGQEIFNSYGELSNVFLLARYGFTVPENQYDIVHLGPDFMKILKKEEKYQEKVKWWSQVGHGLFSAWYAQMRQEDEEDEDGQAKSDNLSDDIESEEEEEEEEGDDSLESWLSQLYIDSSGEPSPSTWALANLLTLTAVQWESLFSKKATPHISDSIVNEEKLPFLAKKDNPHSKKLLSNLLKEKQLPCIKGDNSSKITSATKSMLQNARTLVQSEHNILDRCLKRLS