lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Sequence:
MAASYRSTDWFPPTTTTGSFTGLNTDQSVLQDQDIVSSRPFCGQGTESFHIGADTPRSNHSHSDVPSFDKVSPGMINEMFYHSNGVPSDFQRSSLSTRNQSSLQHYGDLYADDSRYFVPFHLSNQQYPTPEDIHLSPEFHMFQANSRHFDRHVNERNSSEIDNMMRARGNSVLRDNIYGEPRGMNLNPFSGENMFPPLASTRPCMRHLGSAELLANDFNMGPAHGGLHDAFESAANLSYREQAYAQCKRSPFSASSSSPTWENDYNLPPLDEARSESYNDFSHCPAMLDMLTESNRGPRASRLNSKSKMISYDRVDRFCQQELLSQFRDAKFFVIKSYSEDNVHKSIKHCVWASTKNGNKKLDAAYREAKKKDVACPVFLLFSVNASSQFCGVAEMVGPVDFNTSVEYWQQDRWSGHFPVQWLIVKDVPNSLFRHIIIESNDNKPVTNSRDTQEVGLEKGIEMLDIFISCEMRSSILDDFNFYEERQIAIQDRKARQRAVLESLALSATSAPTYSLHDDFVREMSKHFAEALALQHRPK
The following text describes a protein:
Function:
3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.
Subcellular Localization:
Cytoplasm. Cytoplasm, P-body.
Sequence:
MESNNNNNNINIINNNNNNNNNNNNNNNVDKTDNRNNENKNKKNMKSKAKVEWVPKIKPAESTTSTAITSDKEPSTAIPTTKTTATTTATKTSTVSQPQKESKKPKKGDVKKSNIDIEKSLSNLSLDSNKPSQRSKKEKSLDSIAQENLLDPPNQMASTTTATSTENKIPKPRKERNKKPKGISITPSVASTESHAQSSTNESVPKAKQNNKDGKKENKPAKQPQQKKDTKPSAPAKQPPQQSQQPPPQQQLGQPIEQSQQPLQQQSQPKQPKQQKQKQSKQSKQSQEPLQQQSQSNKDLGEPENKDKKVRRNNRNKQDKEGKEVVAKEKKEGKNKTDKKEKKDEKETKGYRERRREKRERERNELKSKKIGSNDSNGSNDGNNRKGEKKKRQFYTPYITKEQLDQGLAEGKYFFGTLRVNSKKYRDAYITVDGLLHDVYCGGLKDRNRAFNSDIVVFEVLDEKEWKKRPSKEDEEDDITANAALKDATVDPNESDEGTVVLLENEDFNKKLEAENKLLKECITAETPLNHEAKEKEDDIKENIESDESDDSESESDSTDEGFVKIKVKSEKEAIHHTLDTDTQTITSNATTITTTVTSDLSTNSGTPSKQSNTPTAPIRDHNIGKLEKLVIKAYDSKLYVSVKIVYVLEVKHTRNHVGILIEENENSIFTSFAPMDTSLPKCCIFKDSIPQYKSESEKYKRALVMISYSSWKDTALLPCGHFISLFGECGKIEPETHALLSEFGVETDPFSREVMDCLPKVPNSSKWLPSKQDLADRRDLRTYEICTIDPDTAKDLDDALHCIELPDGNFEVGVHIADVSHFVKSGTELDKCAQRKATTVYLVQKAIPMLPSLLSEELCSLNMGVERLAFSVIWKLSPSGEILEEWFGRSVIKSFCRLTYGIAQALIDDKITNCWEDFVPKEKVKKELGPNTPEHILRVKKSVMGLRGIAKCLRNTRIENGAFTIHPSKLAFELDEKGNPISTKIYPIYESNNLVEEYMLLANMRVAERIAKFFPSNALLRKHPSPNENKLESFISFCAKHGFEIDTSSSLTFGESIKKLKETVGDIDILMAIQLLSIRSMKLAEYFCTSTEEEEDWRHYALNAPFYTHFTSPIRRYADIIVHRLLDLSIKIENASTDKHKEEILGTLFSKLPSSELVCTIAKNCNEKKLNARKAQERSDKVFLCVLLENHPTTCGAVALNTGSTFITCIVPQFGSEQKIYLEDLKEKGDILDHSYDASTGENLVKWPALNDGQPDIIQRISQLTTMKVLIVVNKEKFPIDTKCFLVHPNL
The following text describes a protein:
Function:
SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity). Is probably part of the SOS regulon and involved in DNA recombination and repair.
Sequence:
MKIIHTADWHLGKILNGKQLLEDQAYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIIISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPEIDEDAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAKGYRRVTINDGIINDVFIPLKPLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNETFNYNEENNAIEISEKDDMSIIEMFYKHITDKELSDIQSKKIKNILENELRKED
The following text describes a protein:
Function:
Probable component of a transcriptional corepressor complex that acts downstream of MAX2 to negatively regulate karrikins/strigolactone responses. Probable target of MAX2 during germination and seedling photomorphogenesis. Acts probably specifically in the karrikin pathway.
Domain:
Contains 1 EAR motif required for the interaction with TPR2.
Sequence:
MRAGLSTIQQTLTPEAATVLNQSIAEAARRNHGQTTPLHVAATLLASPAGFLRRACIRSHPNSSHPLQCRALELCFSVALERLPTATTTPGNDPPISNALMAALKRAQAHQRRGCPEQQQQPLLAVKVELEQLIISILDDPSVSRVMREASFSSPAVKATIEQSLNNSVTPTPIPSVSSVGLNFRPGGGGPMTRNSYLNPRLQQNASSVQSGVSKNDDVERVMDILGRAKKKNPVLVGDSEPGRVIREILKKIEVGEVGNLAVKNSKVVSLEEISSDKALRIKELDGLLQTRLKNSDPIGGGGVILDLGDLKWLVEQPSSTQPPATVAVEIGRTAVVELRRLLEKFEGRLWFIGTATCETYLRCQVYHPSVETDWDLQAVSVAAKAPASGVFPRLANNLESFTPLKSFVPANRTLKCCPQCLQSYERELAEIDSVSSPEVKSEVAQPKQLPQWLLKAKPVDRLPQAKIEEVQKKWNDACVRLHPSFHNKNERIVPIPVPITLTTSPYSPNMLLRQPLQPKLQPNRELRERVHLKPMSPLVAEQAKKKSPPGSPVQTDLVLGRAEDSEKAGDVQVRDFLGCISSESVQNNNNISVLQKENLGNSLDIDLFKKLLKGMTEKVWWQNDAAAAVAATVSQCKLGNGKRRGVLSKGDVWLLFSGPDRVGKRKMVSALSSLVYGTNPIMIQLGSRQDAGDGNSSFRGKTALDKIAETVKRSPFSVILLEDIDEADMLVRGSIKQAMDRGRIRDSHGREISLGNVIFVMTASWHFAGTKTSFLDNEAKLRDLASESWRLRLCMREKFGKRRASWLCSDEERLTKPKKEHGSGLSFDLNQAADTDDGSHNTSDLTTDNDQDEQGFSGKLSLQCVPFAFHDMVSRVDDAVAFRAVDFAAVRRRITETLSERFETIIGESLSVEVEEEALQRILSGVWLGQTELEEWIEKAIVPVLSQLKARVSSSGTYGDCTVARLELDEDSGERNAGDLLPTTITLAV
The following text describes a protein:
Function:
This protein binds RuBisCO small and large subunits and is implicated in the assembly of the enzyme oligomer.
Subcellular Localization:
Plastid.
Sequence:
MAQSQLAKGSRQTTGRPFQNKPARAARRLVIRAADAKEIVFDQESRRRLQAGINKVADAVGVTLGPRGRNVVLEQKFGVPQVINDGVSIARAIELKDPVENAGAQLIKEVAGRTNDAAGDGTTTASVLAREMIHYGLQSVTAGANPIAVKRGLDKTAEYLVAKLKEHAKPVKGRDDIKVLPYGDSLDDLRCMWNGFSFAECLVNKRLNGLDMGRGLLPVEFQHLLARTRHELAGLMGAEAEVRVGTPVRLAQSGPAADPLPPGGGSDTLHQVAYTDLMAANAESLLRSHAAEHVPILWLDRLVGNVTGLPADVAKVYDNWKSVCRALHYFTLQPDQRRDWRVKDLLEARASQNLAGRAEFRTTFIAAQMCQARSFTLLVSLLIVVGSLQWASGSDKVFIATKGDEPSKGHDISLELNDDCTGLSSVLLASCRELGGGSGHYATGSGDLQHAHGAADVDRRRQLASASKLSFTLRLAGGGRVSPSGTAKSGWLQASADGGATWGAVCSKHWGSEEATVACRQLGGGSTALGLPRSAASAGFAASVPAPTAAAASALLHVQSVTAGANPIAVKRGLDKTAEYLVAKLKEHAKPVKGRDDIKNVASISAGNDNAIGEMIADALDKVGSNGVLSIETSNSTETVVEVQEGMEIDRGYISPQFVTNQERLLVEYDNCRVLVTDQKIDAIRDIIPILEQVTRLNAPLLIIAEDVSGEALATLVVNKLRGVLNVCAIKAPGFGERRKSLLQDIAIVTGAEFIAKDLGMKVEQAVVEQLGVARKVTVANNTTTLIADAASKDEIEMRIAQLKKELAETDSVYDTEKLSERIAKLSGGVAVIKVGAATEAELEDRKLRIEDAKNATFAAVEEGIVPGGGAALLHLSELVPAFKETLTDAEEKLGADIVMKSLRAPCRLIADNAGVEGEVIVQRLLGKPFEVGYNAMIDKVENLLDAGVIDPAKVTRNGLLNSVSIAGIMLTTQAVMVEKHKPSEIPGGMTASGMPSGMTI
The following text describes a protein:
Function:
An odorant receptor which affects chemotaxis to the volatile odorant diacetyl. Specifies AWA neuronal cell fate via the odr-7 pathway.
Subcellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein.
Sequence:
MADREWIVVTDTAGPVGFCLSIISNTTLLFLIFSRSSPIKGPYKKMLIVLCIFTVFYSFVEIMLQPLIHLYDDTLFLIQRKRFDLSKTITRLIPTTYCWCYAMSFCLFALQFLYRYVAVCKPQYVGYFAGCYFYYWLALILSLATSWGLTAAFMFPQTNRTTESFLYVIETSYDLDPYWADYVAYKYFDTDENHVRHINVLSFFGVLQHGLVISLSFGTLFYCGVQTYVNIKKHTGMSEKTRSLQLQLFRALVAQTCLPMFMMYIPIGFMFSCPYFDLQLGAVTNYQTVMAQLYPGIDPFVVLFLIDAYRRTILNSICPRFLHKKVLHKTISQPDVSMFSVSVKPSISSNGLTSTSRMS
The following text describes a protein:
Function:
Inhibits Na(+),K(+) ATPase by the competitive mode against Na(+).
Domain:
The repetitive domain of pro-SPAI serves as a substrate for transglutaminase.
Sequence:
MRSRSFLVLVAVFLICETLVAQRLDRIRGPKGQGQDPVEGQDQDEGPGPVKVEILDIGQDPVKGQDPVKGQDPVKGQDPVKGQDLVKSQDPVKAELPDIGQDVVKGHEPVEGQDPVNAQLPDKVQDPVKAQPAVPGRFLLSKRGHCPRILFRCPLSNPSNKCWRDYDCPGVKKCCEGFCGKDCLYPK
The following text describes a protein:
Function:
Functions as an E3 ubiquitin ligase.
Sequence:
MAGSGSWDGSQSDNSSQFEPGIDNIYEAFICPLTKQVMHNPVTLENGQTFEREAIEKWFQECRENGQPLSCPITSKELSITDLSPSIALRNTIEEWRARNDALKLDIARQSLYLGNAETNILLALKNVREICRNIRKIRQRVCNPQLVRLITDMLKSSSHEVRCKALQTLQVVVEGDEESKAIVAEGDTVRTIVKFLSQEPSKGREAAVSVLFELSKSEALCEKIGSIHGAIILLVGLTSSKSENVSTVEKADKTLTNLERSEENVRQMAINGRLQPLLAKLLEGSPETKVSMAFYLGVLALNNDVKVIVAQTVGSSLIDLMRTRDMSQREAALGALNNISSFEGSAKLLINTGILPPLIKDLFYVGPNQLPIRLKEVSATILANIVNIGYDFDKVPVGPHHQTLVSEEIVENLLQLTSNTGPEIQGKLLAVLVGLTSCPNSVINVVSAIRNSAAIISLVQFVEIHENDDLRLASIKLLHNISPHMSEELANALRSTVGQLGSLVSIISENTPTITEEQAAAAGLLAELPERDLVLTMRLLREGAFEKIISKIVGIRQGEIRGIRFERTFLEGLVSILARITFALTKETDATLFCCEKNLPSLFLDLLQSNSQDNIQRASATALENLSLESKNLTKIPELPPPTYCVSIFSCLSKPPVVLGICKIHQGICSVRESFCLVEGQAVDKLVDLLDHENDKVVGPALAALSTLLEDGLDVVQGVRLIDEADGITPILNVLLENRTENLRIRAVWMVERILRIEEIAREVGEEQNVTAALVDAFQNADFRTRQIAEKALRHIDKIPNFSGIFTNIG
The following text describes a protein:
Function:
Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable).
Subcellular Localization:
Cell membrane; Lipid-anchor. Cytoplasm. Membrane raft; Lipid-anchor. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Sequence:
MKKHISMLFVFLMAVMVLSACNSSESSSNSEVSSSKTRTVKHAMGTSDNIPANPKRIVVLTNEGTEALLALGIKPVGAVKSWKGDPWYDYLKDDMKGVKNVGLETEPNVEAIAELKPDLIIGNKVRQEKIYDQLNAIAPTVFAESLAGNWKDNLTLYANAVNKADKGKEVIADFDKRVSDLKNKLGDQTNKTVSVVRFLSGESRIYYTDSFPGIILDQLGFKRPEKQVELFKKQKDQFTFSTDSKESIPDMDADVLFYFTYKADNAKENEKWANQWTSSSLWKNLKAVKSGNAHEVDDVVWTTAGGIKAANYLLDDIETYFLKTK
The following text describes a protein:
Function:
Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity; Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis. Plays a role in epithelial cell junctions formation.
Subcellular Localization:
Cell junction. Cell projection, ruffle. Cytoplasm, cytoskeleton.
Sequence:
MVEVVVEYEYEALHEDELTLRLGDIIKNVRRIEEEGWMEGDLNGKRGLFPDNFVKEVRKDEPKSKEESKEPKEAKEVKEESTIQRRASGNVASLVQRISTYGIPAGGIGLQPHSQPRASKKKLKKRQCKVLFEYVPQNEDELELKVGEIIEITEEVEEGWWSGSMNGKSGLFPSNFVKEIDSTEDAENSDVTEEQDTRDGTSSPTSPHPGNGVMAQPKKIKGIGFGDIFREGSVKLRTSLKGPSENMEKTEKPIPPLPSATKPTPLSTPEHPKGEKEAESKAKVKEYCKATFHYEATNQDELDLKEGEVILILSKDTGEPGWWRGEVNGKQGVFPDNFVSLLPESDKETLTSKGSIKVLSKQEPEERPKKPPPPSKSTVLKPETPSVDKKQPQPRPEDKVVKPLPEKPAKPAGPIVPPKKPVPPSKSLLRPSYHTKRPDLPLTPSPAAKQNGDVPLSRRKSECEPVPIKPKTVVDIGEKSTETVNLMSFDDVSSSSEKLSHPTAQRPKMPGKRPPAHRGHSPSKDVGEKAEKTEKIDEVETAPSPAPAPAPAPSTQNSIKMPISSPLPSTTPKTISATLITPEPKPKPDKEQEKTSELEELKDQIKDLVLSVELLKTQQSRELGELRKELDDERLKRVALQMEIDKLKKICVQST
The following text describes a protein:
Function:
Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response.
Sequence:
MASKKLVNSVTGCADEALAGLVACNPDLQMLQGHRVALRSDLESLRGRVALLSGGGSGHEPAHAGFINKGMLTGVIAGAVFTSPAVGSIVAAIRSVAQAGTAGTLLIVKNYTGDRLNFGLAREQARAEGIPVEMVVVGDDSAFASLKKAGRRGLCGTVLIHKVAGALAEAGVGLEEIVRRVSAAAAAMGTLGASLSSCSVPGSKPTFQLPDDEMELGLGIHGEAGVRRMKMATADELVKAMIDHMTDPSNESHVPVRAGSAVVLVVNNLGGLSFLELGIVADAAVRCLEARGVKIARALVGTFMSALEMAGVSLTLLLAEDALLQLIDAETTASAWPRVARVPVTGRPRSRAAPAEEPEGPEPAAAEGAASRRAALVLQRVCATLLGLEEHLNALDRAAGDGDCGTTHSRAAKAIQQWLEERPPPSRPDHLLSALARLLLEKMGGSSGALYGLFLTAAAQPLKTTAGLPAWTAAMDAGLEAMQRYGKAAPGDRTMLDSLWAAGQELRALQSPGANLLQVLSRAVQSAEAAAEATKTMEAGAGRASYISSARLEQPDPGAVAAAAVLRAILEALQSQAA
The following text describes a protein:
Function:
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
Subcellular Localization:
Nucleus.
Sequence:
MVNVRVRVRPLPAYHRPNKVDHLEIDSYERLETIQEKYSTTGSTTRLYYEGHELPLNSSIGSHNFEDDAILECCRSPSISAALSACLKDLDDVKKLDAAERTRHNLLRILQLPLHIASNPTHDIWQASSWTEDSLKSRIINFATMKAVLQRTDRYQAHDLPQCTDCKSLFDALKQHNVWNGGNRGGRTNGRNNFNSQSHIFKPEKKDGNPSTNWLLLDEKLRIQQRIRMEYSRGFGALDDYIEEFVKRDHERHENKNPRGQSVRSSTACSPVRSKSLLDDSESYLQHLAATPPPSSGRQTQGGAPFDLGATIFSPRRTPPNNNSNNKYIPQYASGPFSVLATLYNAMKAKHPLAMGQRLLTLSEDQLKRMAQPKCRANLYDKMRIRGRNAFACMDGLIEKQLVRKEIVRDTINGGEIEKWGLLREGEILGGFCAEFERAVDDAMPVKEMFEHSATASARLVLCIDSREDDLFRQRMKWSCEDENIPFAEKDLPAGDYIFLNELQNKLVPVVFERKSWSDFADSCLGKGRALNRLDCVKLNSNGLVTSCQGNCQLCKMKRSGCKQIVFIIEGARCERKVGARRTPKLCTTHDCCGICKELKERHNVTQDALEGLLTRLQVEHGCYIHYTRSFNDTVQSLFTIRTLLQSRPCFASRLLRESSSLDGLLAFSEYASNARSRQGTISSKLLPLETVHEREVESLASVIGVGRWDTDLAQQMIGLYPLLAGKSSSNQPRQRRGLPKETLLLDSDSDEEVKEVFPTKSNPETICIDTDSENESGKTGKQRVSQGGAKTSYNSDVEVVDARNKSDDSIIVLDDEPVFSKKQNVHQPNVDYTKKLIILREWDPYDQKVSKSLEKMWRQLYSCDCQLGSFYRESSSLLEGTIASSALPHLNRRTLMSFTLFMQLALGVHIRSVQSDVVTSDIKTLLRQNGSTTASKPPSQSCTRTPAKTARPSINTSNTAPKPPRESSASLHGGSAMSVDRPRLSSMNSERDAAREARLRRFDSTSSCSIILPVNLQMGQSKQSAGWTCPCTLINTPSSSLCESCGSSRPGSKQSSSSYYTRPPPQPRRPISSNDALLAEWKCPLCGLANPPRDEACDVCATPRPGYQALLVSASASSAKKWSCSHCTLENEEGTDECSACGNANERPTKYARKAPPGETETESTPKRVARCGACGVEGHTRANATVQNCVAYNDDIEVDRREKQRLKKDQAIVAERDRIQRK
The following text describes a protein:
Function:
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Sequence:
MHEASIVTELLRIASDECSKNGYTKIDSIKVIVGRATGVMTDALLFAFNVLKEDTLAKEANLIIEEIPVRGVCKDCGKEFESNENYLIFECPSCGSFSVNIISGKELNITEMEVSQ
The following text describes a protein:
Function:
Histone demethylase that specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2), thereby modulating chromosome architecture.
Subcellular Localization:
Nucleus.
Sequence:
MFISGRRTADKWRAEERLQCPAGSARAALARCADGGAVGPFKCVFVGEMAAQVGAVRVVRAVAAQEEPDKEGKEKPHAGVSPRGVKRQRRSSSGGSQEKRGRPSQEPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPAVAAPLPAPSTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGPDGDPSSCGTDLKHKDKQENGERTGGVPLIKAPKRETPDENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNKEVQTVCAGLTRISKEILTQGQINSTSGLNKESFRYLKDEQLCRLNLGMQEYRVPQGVQTPFMTHQEHSIRRNFLKTGTKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKKDIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLRLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHPVVEATQNTESNSNMDCGLTGKRELEVDSQCVRIKTESEEACTEIQLLTTASSSFPPASELNLQQDQKTQPIPVLKVESRLDSDQQHNLQEHSTTSV
The following text describes a protein:
Function:
Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Sequence:
MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDVCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPWLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVHGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSVHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAAPRCSPALLLLTALLGTASPLVF
The following text describes a protein:
Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Subcellular Localization:
Late endosome membrane; Peripheral membrane protein.
Sequence:
MTSPLLLSDCKKAVSDLKSLSNDELDKIMNDEEKIENILSSLDQSYLKEIETQKERLLESNRALAEENLSREPELVEGREKLQELSEQAEQLSKSVEEKVKQIKNKSGDLSLETSLALLQTAASEMEEKSDKLVKSFLENEIDLENFLDEFLTKRRQVHLRLIKAEQLSKIISRGPMGGTSNYVNAPAIPINSNYFPGVPSQNVPYPTGPIGMPMPGLNYFQNHF
The following text describes a protein:
Function:
Putative component of the spliceosome which enhances the formation of the ATP-dependent A complex of the spliceosome. may participate in mRNA 3'-end cleavage. Also mediates increase of mRNA abundance and translational efficiency (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MLISTFVFLLYEVTALSTAIHVTKSYTHTRTGTSFFMYQKEAFYRGRSSTRQFNNTRSPSGRSASRSSNFSHRSSSRDSFSSNRSYSSSLSRSPEEPLRTILVENLTRNVTKEHIAEIFGIYGLIDHIFMPIYKKSELNKGYCYIEYVYHDQAANAVDKMNNAELDGEELFVSIKRFPFESLHKNHKHYENSYRPSRSQNNSHYNDKSFHRSRYSRARSRSPGSNISEYSDQSPPYHSYRHRP
The following text describes a protein:
Function:
Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole.
Sequence:
MAAPCPEDPSLERHFKGHRDAITSVDFSLNTKQLASGSMDSCLMVWHMKPQSRAYRFAGHKDAVTCVNFSPSGHLLASGSRDKTVRIWIPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQKFLFSLSQHINWVRCARFSPDGRLIVSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVDFHPSGTCIAAASMDNTVKVWDVRTHRLLQHYQLHSAAVNALSFHPSGNYLLTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDVVDYREVIKVHRPPAPLATSGNLNVQTRCEDCWPEVDFPVPPGGGRSQESVQSQLQEPISMPQTLTSTLEHIVGQLDVLTQVVSTSSRQSIQSIARPTWTARPHRVAHHPPQCWAWGACGSAPTAQTGNQTESCPAVPPSRTAAPCHPANQPSPSRSCPTSTSAVPRTPLTWTCSASTASSISSTSRLTCPTPLSMVASSPISRSPSPTTGARTSPSSFPRPSASLMRPAPRSVASWCTA
The following text describes a protein:
Function:
Involved in vacuolar processing and morphology.
Miscellaneous:
MISCELLANEOUS: Present with 1050 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MNTALDDLHGDLVTLEDNEIINNSDHSSSHSTSHEEEDEEEDDTEDIELIEKDGNKILSSRIHPEDEIINDGLNIWIPVQMLKKNIAKFWSHFLAIEKKLTKVKCKHCGEILTRSDASLTKTFRSHLKTKHNISANKNFYSMNFTVGDSNLKNNTSSTEITRRHGYDSLTFNSDQSFKCFDIGKLQSSNYLSISQLVAIVIASENLPLNFFENVSFKSLLSKFHRIPPLTTNIIEESIIGLSKSIDELIRRSISRNDTQLPFTIHLSDSKESNQPLYLKYSREIRAQLSNLDLSHLISVNFTELAGKRSLFSLQLFDNTNKVSKGLPLSIFVRKTTDIDISVWQEQLNNLYSKYPGLQKSVISITLPQSHYTMVLENRNSHNFTFHSGSVREIKYHTCIVSELLHCFLQPLFNVPTESMLSSFSVAKENHSGGSLLDSLIDFSHIDLSSTILGKICCLIEEVNLNDSLKSDFLLYCQNYTQPNCNELTSILSCNCDRFSALKSILEKFANLVPFFKSINSHLENESLSESDFRLINTVEETLRTFEQSIEYFASSAPLKFTHTLVFIIKFELYLTEIIRSFKFTKSKKPFEKILARLLKVKDLYLLDDVNLIGAFLYPSIFQSKSLLNEIFGTTSVNKIVHNMTKIVLRYLKNFINITNFRSSNSGGESGRNSGNNLLSDYEAIFMKESRDVELLCNTKLTAPLTEDSLLVQIIRDDLLRYVNRIAHELPNAYHDYLNDNDISFDGSHFTKHELSEENDSNSGEWCLNPMEETFDIHIPISDSIWNNYISSKNKIEVIDILLQLLSVNSTSSIRSELSSLTANQDFSTKLSEETIKIKLLNSQFNLEKINFHSGSIFDAC
The following text describes a protein:
Function:
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.
Sequence:
MQRAAVLVRRGSCPRASGPWGRSHSSAAAEASAALKVRPERSPRDRILTLESMNPQVKAVEYAVRGPIVLKAGEIEMELQRGIKKPFTEVIRANIGDAHAMGQQPITFLRQVMALCTYPNLLNSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAFITRRDGVPADPDNIYLTTGASDGISTILKLLVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEDNCWALNVDELRRALRQAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYQMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVPGEESFEQFTREKESVLGNLAKKAKLTEDLFNQVPGIQCNPLQGAMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLHKVKDFHLKFLEKYS
The following text describes a protein:
Function:
Plays a role in splicing of the U12-type introns. Implicated also in removal of U2 introns positioned adjacent to a U12 intron.
Miscellaneous:
MISCELLANEOUS: Maternally imprinted. Active paternal allele is unmethylated whereas the inactive maternal allele is highly methylated.
Subcellular Localization:
Nucleus.
Sequence:
MASRQTAIPEKLSRKQYKAAMKKEKRKKRRQKMARLRALEAPPEEDDDVSANEELAERLLEIERQRLHEEWLLREEKAQEEFRIKKKKEEAARKQKEEQERQIKAEWEEQQKKQREEEEQKLQEKREREEAVQKMLDQAENERIWQNPEPPKDLRLEKYRPSCPFYNKTGACRFGNRCSRKHDFPTSSPTLLVKSMFTTFGMEQCRRDDYDSDANLEYSEEETYQQFLDFYHDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCEFCPVTRWKVAICGLFEMQKCPKGKHCNFLHVFRNPNNEFREANRDIYMSPPAWTGSSGKNSDRRERKDHHEEYYSKSRSYHSGSYHSSKRNRESERKSPHRWKKSHKQTTKSHERHSSRRGREEDSSPGPQSQSHRT
The following text describes a protein:
Function:
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Membrane; Peripheral membrane protein.
Sequence:
MTTDLLRISLPLQPKSTTFSHRILTCNVDYKRHRGYLYRPPPRIVHKHLPNLLVLAKAVDLNSPSQTTSEKLQQPRREDQPSVLLDVTGMMCGACVSRVKSILSSDQRVESVVVNMLTETAAIRLNADAEVSGANAADEFARKLTECGFPSNRRASGLGIEEKVRKWKETVARKEALMVESRNRVVFAWTLVALCCGSHASHILHSLGIHIGHGALMEILHNSYFKGSLAIGALLGPGRDLLYDGLKAFFKGSPNMNSLVGFGSIAAFMISAISLLNPDLGWDATFFDEPVMLLGFVLLGRSLEERARLRASSDMNELLSLISTQSRLVISPSESDSSTGSILSSDSICIEVPTDDIRVGDFVLVLPGETIPVDGKVIAGRSVVDESMLTGESLPVFKEEGLFVSAGTINWDGPLKIEASSTGSNSTITKIVKMVEDAQGREAPIQRLADSIAGPFVYTVMTLSAATFAFWYYVGVHVFPDVLLNDISGPMENPLLLSLKLSTDVLVVSCPCALGLATPTAILVGTSLGAKQGLLIRGGDVLERLANIDIITLDKTGTLTEGKPTVSSIASFIHKEHEILQLAAAVEKTASHPIAKAIINKAELLNLNIPVTSRQLVEPGFGTMAEVDGCLVAVGSMKWVHERFQIKKNISEVMNLEKDVMKKSSQGRSSSNYSQTVVFVGVEGEGIIGAIGISDNLRLDAESTVKRLQQKKIETILLSGDREEAVASVAKTVGIQTHLINASLTPQQKSDAISTLQSSGHSVAMVGDGINDAPSLALADVGIALQVEGQENAASNAASIILLGNKLSQVVDAVDLAKATMSKVHQNLSWAVAYNIVAIPIAAGVLLPHFDFAMTPSLSGGLMAFSSIFVVSNSLLLQLHGSHNKKMKNEGEKRIESTSLRA
The following text describes a protein:
Function:
An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MGPGSQRALFLLLLLLASPGARAFQSCLNKQQLLTTIRQLQQLLKGQETRFTEGIRNMKSRLAALQNTVNKMTPDAPPVSCPALEAPPDGKKFGSKYLVDHEVYFTCNPGFQLVGPSSVVCLANGSWTGEQPRCRDISECSSQPCHNGGTCVEGINHYRCICPPGKTGNRCQHQTQAAAPDGGEAGDPAFSRAPRCAQVEREQHCSCEAGFHLSSTTGGHSVCQDVNECEIYGQKGRPRLCMHACVNTPGSYRCTCPSGYRILADGKSCEDVDECAGPQHMCPRGTTCINTGGGFQCVNPECPEGSGNISYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSKLKTPITLFRMATASIPGHPGPNSLRFGIVGGNSRGHFVMQRSDRQTGELILTQTLEGPQTLEVDVDMSEYLERSFQANHVSKVTIFVSRYDF
The following text describes a protein:
Function:
Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species. Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1.
Subcellular Localization:
Nucleus. Nucleus, nucleoplasm. Chromosome. Cytoplasm, cytoskeleton, spindle pole. Note=Predominantly present throughout the nucleoplasm during prometaphase, metaphase and anaphase. Is also detected in nuclear foci that are not identical with Cajal bodies. Starts to accumulate at chromosomes during telophase, and is nearly exclusively associated with chromosomes in newly divided cells. Colocalizes with MAD1L1 at mitotic spindle poles during metaphase and anaphase.
Sequence:
MPERDSEPFSNPLAPDGHDVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKSYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRERDRERDRERERERDREREREEEKKRHSYFEKPKVDDEPMDVDKGPGSAKELIKSINEKFAGSAGWEGTESLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKRMEADGVEVKRPKY