lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the intraflagellar transport complex A (IFT-A) involved in flagellar assembly.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, flagellum basal body. Note=Localizes to the cytoplasmic and membrane-bound portions of each of the eight axonemes, localizing particularly at the flagellar pores and at the distal flagellar tips. Localizes to the basal bodies.
Sequence:
MPSTAFILKCLEFTDTGEEVVLVAWNKTENYIAAGGQTGSIRILLLDFNSLSEQGYNISDLRTSTRNVRILMDKKLSLHDNALITSIAWNEKETKLATSDNRGLVFISSTDTGKWVRNLVNDSNRAAVVTTTWSPDASRILMVYVNGLVMLGTASGHRIYNGTINKGSAPKFGLIASNAIEVFILAWGNAICCYNFSGEEVWSVSPLLATNSDNHFVHGCWGHSSESAQLTALSPSRDPACNGSSMPQIKINSFSGDSMTLIAVTSNGMLCVYSVLTGELLSSVSTEIIPVNVQLSPGSHMLCITGSVQSSDSNFGLHQLRGNQGVSGDSTKHTAIVVVYRTADLATISRLRLPERVATSSSWDSTGLRLVLAAGKNIYIATVRPSYNHYLMNDGTMAFTMSNYTSTILSTASFVDDTQRPPMNVGALFSKKTAEEAPSSAISSFEERILDRARCNECVLFWKPGLQAPYQRWPARMIAVVGCKSYIAILTLKTNTSGTRKHHTHICFYTSVCAPIFSIDLPYVPFYTAGSGNYLVCASSSRISVVDIRGLANEAIGLVDAENVSYVYEWHADSYPLAQDRELTVARLTVNNPIVGVACCDVALFVARQDERVQRYSLPSLTLLETMTIKPNQEYMQTNCNGTVLACLHEDGSLVFYYTQSYYSEFLYAHHNPAEQQQQKQQPAPKPPQAQAHLTLLDTDADTAAALGFGQDSVVETESAPYVIKNSVLKNVNVSSGELLQDSAQARSGGVSTIPPYSPELIGIWGLVFSPEDPNLVAVSSQYKVIVFHLDTQTREDSIQTSAHIIGFSGLSIIASYLDEVSHNISSLDHAYYVLETQMLRELQEIIFGQQQAPESFNPLVDAALNRGCLNKNMISLTSDSKSGVPSSLFDSVAPKTIAIKPVRGQQPVGDMVDSGLDVTASNSSQPSTQTSQALYSKDGQISINLAGAVEYVKSHPSVHLYRIVAEASLITLRLEVASYFYIRAGDYVSYNFCESLLRLQSQDQRRAEMLMLIGNFSSAEHVYKQVLGRPDLIVKTQTDLQMWLSIIRAAKLSRTPGGNLLIDDKLLEKAHKSIGLYYMRQQQYAIASDFLQKSGDPYLYAESLFAARRYAELKALAVSLPVDEFANCIAKVAVMLARLGDVEGASEALVRVNDPHSAVHISLQLKRFDIAAAIAGKHNILHIIDRELSVYLKQLLAAGDDQGALELLRKTKQGEVIAAVIINLVLKELQTIFVNRTFPMPPGLFSKLRRIIVLAGKEATYVQREQAKKNLQAHASAAPDCMLTEQATNAAIDTFINEDDNSKAVHDVKAKNTGKEASSLEHELENAQSRLRSVPVIWRIARQTRFIVLSSYMLYIGNPEQALWPAIEAANYYHRTNDSQSSADPCIQYLSRIALPIAAQAALLFGDFELASNLLELIEADTELPASERDQLEQMSVLIYSEYNITSVPSKRKDNYQINCGHCNTLLPPYCGMCEKCHWQTPICVRTGQPIKSDKMDKTVLCQMCRSLATMGKTHLSVCPLCHEPYQ
The following text describes a protein:
Function:
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
Sequence:
MAKSASNQLRVTVRTETGKGASRRARRAGKIPAVLYGHGAEPQHLELPGHDYAAVLRHSGTNAVLTLDIAGKEQLALTKALHIHPIRRTIQHADLLVVRRGEKVVVEVSVVVEGQAGPDTLVTQETNSIEIEAEALSIPEQLTVSIEGAEPGTQLTAGQIALPAGVSLISDPDLLVVNVVKAPTAEELEGEVAGAEEAEEAAVEAGEAEAAGESE
The following text describes a protein:
Function:
Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
Domain:
Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.
Sequence:
MTFSFNKSRPPYPYLSAEIEGSFAYRTVKDRMPVILTKVIDFLCRSKNEIVQSSHSEAAALEDLKLIIGKLSKLRSEMQTNKTLSKFEIDCPHLQDSEKWNTELIETKDSAAPCWFNSPWLLVECYMYRAIYYMFNDSLYLKGFDPFSHMKEEAFFVQKNIICQLASYTNGLCLKSNYSSSELHVHFMKLIEICLWGNRNDLSLSAGNTNTEVKSNSFFDDIKQLNSHILVNNINEVWLHMEHIQNNPYDNKELSIIMDNSGLEMVADLCLAVYCISHKLFDRVNFYVKKIPWFVSDTTCNDLKWALQYMENDCTELQHFAEKCRAYLHSNQFQVLEESYFTLPLPYHVMQEEDPKLYKKLCRSQLIIFKGDLNYRKLGGELCWPSSTPFKTFLQGFSPAPLLALRTIKAEIICDLPSSKIKELDLLDKDWMTNGNYGLIQFAK
The following text describes a protein:
Function:
Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate (beta-HBP) intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
Subcellular Localization:
Cytoplasm.
Sequence:
MKLIILDRDGVVNQDSDAFVKSPDEWIALPGSLQAIARLTQADWTVVLATNQSGLARGLFDTATLNAIHDKMHRALAQMGGVVDAIFMCPHGPDDGCACRKPLPGMYRDIARRYDVDLAGVPAVGDSLRDLQAAAQAGCAPWLVQTGNGRKTLAQGGLPEGTRVCEDLAAVAEQLLQEA
The following text describes a protein:
Function:
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
Sequence:
MIRGLKAPSFMDLALKTAENAGKAGEVPIGCVVVRNYEVIATAANRTLTDYDPTAHAEIVALREAAKKIGSERLVDCDLYVTLEPCTMCAGAISFARVRRLYYGAADPKGGAVESGVRFFASPTCHHAPDVYSGVGESEAARLLKEFFRERR
The following text describes a protein:
Function:
Probable sodium channel subunit. Required by a subset of neurons.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSNHHSKTKKTSMLGREDYIYSHDITNKNKKEKLNGASKNNDYNQDDDDETMKSKMMDFCDKTTAHGAKRVLIARNSFSKLMWGLIIFSFLLMFAYQASKLIFKFSAHEKITDISLKFDDVEFPAITFCNLNPYKKSLVMMVPSIRDTMDVYDNAKTHSKSEGEKKKPKVSRKQHSDASQQMVRELFAKEIEEGMVELKKSNKTLQSQNKSGRRRSQRSIENRRYEAIEAHCKCVGNIGMECIRFESPPRDPSSKCICTYDRDMEVAWPCFNISVWYDHECPLCHDDGYCESTLPSGTTSSDKWPCMCRNRGDTSERDDTPYCIGKAGVGKIEIRKLWLENNMTTTSTTTTTTTTPPPTTTSTTTTTTTTPPPTTTARPNQRAIVSNPETIKAMGFQGMTDGVAMLTRAKENLMFTMAALSDKQRIALSQSKHEFIEMCSFNGKECDIDEDFRLHVDPEFGNCFTFNYDVNNNYTSSRAGPMYGIRVLLFVNTSDYMSTSESSGVRLAIHPPTEYPFPDTFGYSAPVGFASSFGIKKKVMQRLPAPYGECVETKKVVDRNYIYAGYDYHPEGCHRSCFQNGLIDDCSCGDPRFPVPEGYRHCSAFNATARTCLEKNIGSVGDFHHITQKMDKCVCKQSCEEIIHEVTFSCSKWPSGATDLGDCDGMTESECEQYYRLNAAMIEVFYEQLNYELLQESEAYGLVNLIADFGGHLGLWLGFSVITVMEVCVLLVDMISLFFKSRHEEKLLRQSTKRKDVPEDKRQITVGSGRKSDAFVSI
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MEAKLFFFAIGWWLCCYHPWTNVHGEYYSSVEQMRKLLKLEESLVTSLGQYIKLHEQKIEFLHRQRDLLEKELKKGLKDDIEYSSNPVSAFLMVNRLVNDWERLRAFMDMDVGAKLQNTTEMPTHEDLIGVVEGLARLQDMYELNAKEMASGKLLDRTIGRQLKTAECYEIGNKLTAAKSYRHAVSWLRESLRLWTMDSPGVSKVEVMNALSYALSHQGEYEEALELTQKVLKLQPDNQRALNSKEPLEKWIEYKKQHGLPPPVPEPYVKNYPSLCRGDDQRPAKELAKLRCRYEHNRTPFLRISPLKLQEVNHDPMIVMYHDVISNKEIDAIISISKPLMHRSMVGDDHEKAVSKTRTSSNAWLDDVMHPVVRTLSQRTEDMTNLAMTAAERLQVGNYGIGGHYLPHYDYAVAEEGKEVYPSIGKGNRIATVMYYLSDVAIGGATVFPQLGLGVFPQKGSAIFWYNLHANGTVDHRTLHGACPVFVGSKWVGNKWIHERGQEFRRSCELDPKV
The following text describes a protein:
Function:
Cohesin cofactor dispensable during the meiotic division but playing an important role in DNA repair by homologous recombination (HR) probably by helping SMC5/SMC6 complex. Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication (By similarity). Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Subcellular Localization:
Nucleus.
Sequence:
MGPLVEATEFSKEQALTDAAENLLKPHFSTDATLSLLEVMESLLATVEQDLSSSVQKALHPPMRALVSADLLRNPDSDVRVSVVSCLTEIMRITAPEAPYNDEQMKDIFQVTIEAFEKLADASSRSYRKAEVILETVAKVRSSLVMLDLECDDLVLEMFQRFLKIIRPDHPQLVLVSMETIMITVIDESEEVPMDLLEILLTTVKKDSQDVSPAALTLVEKVLSSCTCKLQPCIMEALKSSGTSLDMYSPVVSSICQSEFATTQAHNDVKPKDNEADEKISEGQVVPSDSLEDKLNLGLSRKGTRSKRSARGGTRRANGDEKVITANEGLSESTDAETASGSTRKRGWKPKSLMNPEEGYSFKTSSSKKVQEKELGDSSLGKVAAKKVPLPSKVGQTNQSVVISLSSSGRARTGSRKRSRTKMEETDHDVSSVATQPAKKQTVKKTNPAKEDLTKSNVKKHEDGIKTGKSSKKEKADNGLAKTSAKKPLAETMMVKPSGKKLVHSDAKKKNSEGASMDTPIPQSSKSKKKDSRATTPATKKSEQAPKSHPKMKRIAGEEVESNTNELGEELVGKRVNVWWPLDKKFYEGVIKSYCRVKKMHQVTYSDGDVEELNLKKERFKIIEDKSSASEDKEDDLLESTPLSAFIQREKSKKRKIVSKNVEPSSSPEVRSSMQTMKKKDSVTDSIKQTKRTKGALKAVSNEPESTTGKNLKSLKKLNGEPDKTRGRTGKKQKVTQAMHRKIEKDCDEQEDLETKDEEDSLKLGKESDAEPDRMEDHQELPENHNVETKTDGEEQEAAKEPTAESKTNGEEPNAEPETDGKEHKSLKEPNAEPKSDGEEQEAAKEPNAELKTDGENQEAAKELTAERKTDEEEHKVADEVEQKSQKETNVEPEAEGEEQKSVEEPNAEPKTKVEEKESAKEQTADTKLIEKEDMSKTKGEEIDKETYSSIPETGKVGNEAEEDDQRVIKELEEESDKAEVSTTVLEVDP
The following text describes a protein:
Function:
Exhibits ATPase activity in vitro.
Subcellular Localization:
Mitochondrion.
Sequence:
MLRILIKTEKSVRRINHLRAVLNKDNQHVTCSRHKHDGYVSIGNVKVPVKTPQNPELVPYAYVVENKELPQSILRHMKWLAQKDILGQDVFLIGPPGPLRRLIAMQYLELTRKEVEYISLSRDTTESDLKQRREMKQGTSFYIDQCAVRAAVEGRVLIIEGVEKAERNVLPALNNLLENREMQLDDGRFLMHHKRYDQLLQDHSKKTLDDWQLVRVSENFRVFALGLPVPKYRGHPLDPPLRSRFQARDVYHLGFSDQLEELYKTAPSVNETLLAETLSCASALVTQDSANLGLPHFPLDNLIKAAKIMEKLPKYPIQNLLSRLYPYKLVLNKDGTQAVEDIYKKFDISLNSSVDSLVLKDIHHKNNQAAVTLASNQQTHSFKVSCGDHIHGPRSSVKDEFVATPYHQRLLADLMLSHTAMDVCIVGGKGCGKSSVIREFSRLLNYRTEPVLMYQDMTARDLLQQRYTLPNGDTVWKLSPLIEAAMEGGMAVLDGLNRVNPGTLSILQRLVHDREVTLHDGTRLIRHDKFDGMKEKLNLTDQELNEKSVYRIHPSFRMVGVAEPPTQGSSQQWLNPELLTLFLYHHMEPLSINNEMEIIQKLVPDVSLTEIKGLLKLCQKLRSAKDANSVSLAASLSTRQLVRISKRLAASHHNVNRSELVSDAVHKACLSRFFLTIFIRFSFPKKIFLGEIKEGILKIGDVSAPVYTGDNVEAESSVAKVPDVLFYDNAQHLSVMRDMLQDYNLGEHILLVGNQGVGKNKIVDRFLHLLNKPREYLQLHRDTTVQSLTVQPTVRDGIIVYEDSALVRAARLGHALVVDEADKAPTHVTCILKALLESGRATLADGRKIVTASTSNKEVILLHPDFRMFVLANRPGFPFLGNDFFGAVGDVFSCHAVDNPSVSSELDMLRQYGENVPEASLKKLVAAFGELRDLADRGLISYPYSTREVVNIVKHLEKFPKEGLANVVRNVFDFDAYSKETKEQLASVMHKHGIPVGAKPHDTNLVFCSLPLSVPKLSGYWNLLHQSSSQCEVESFEMSVKGPVHLTVQNYDIDRTEDRGLDFSEQFAHWQLPQFFRTNIITDIAISKSGPVDTVNIFAVNGSALYVNQRGSSVVKYIDMYDVFPNVGSMSHANVKIAPLGPSLQGQLLLFEQKSKFLLMIDTNSGATRRLFIPGMEGTSDPHLSVRRSSSTPSTPPYKMCSEFSEEFCTVVFFEENGNIIASYASVFKFICNPYIVLWGKIGHIITSEPNYDIIYLTHDKWLITEADTNIKYMLSTKSVEDNIPNKLTQLTTSLKQAVDSPNRVLVDKNCYAKCVVGFPDLTAANEIYTFPRTNDTDKGRTIYRGMTKFVPPKPPCQILSDSNQVVKIVPLKSVPDTAFNEGIKPSLTTHCMEVADLGQHMLRYVPLPQAVSESPYVSWQSSISESGYNTAVGKNDVLYTVDAGGCVREWETGLMNLKRSLDEWRAMIGSDGGDDRLQITTERESGEDVTAPKHGKIDPDNAPHVGGNTWAGGTGGRDTAGLGGKGGPYRLDMGHDVTQVPDWEKEAVPEHVKKAARDVAKKAFKERLREIRMSEFDADMYEKFSSHVRKQVKSLRIILDSLQAKGKERQWLKHQTTGELDDMKLIEGLTGEKNIYKRRAEQEPEPGTPQQKPKKIRVVMDVSGSMYRFNGLDNRLERSVEAACLVMESFEGYKDKFK
The following text describes a protein:
Function:
Involved in the transport of molybdenum into the cell. Part of the binding-protein-dependent transport system ModABCD (By similarity).
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MRWIGLSTGLVSAMLVAGLVACGSNSPASSPAGPTQGARSIVVFAAASLQSAFTQIGEQFKAGNPGVNVNFAFAGSSELATQLTQGATADVFASADTAQMDSVAKAGLLAGHPTNFATNTMVIVAAAGNPKKIRSFADLTRPGLNVVVCQPSVPCGSATRRIEDATGIHLNPVSEELSVTDVLNKVITGQADAGLVYVSDALSVATKVTCVRFPEAAGVVNVYAIAVLKRTSQPALARQFVAMVTAAAGRRILDQSGFAKP
The following text describes a protein:
Function:
Involved in the biosynthesis of jasmonic acid, a growth regulator that is implicated also as a signaling molecule in plant defense. Converts 13-hydroperoxylinolenic acid to 12,13-epoxylinolenic acid.
Sequence:
MTISLYTVLTSPSRRRQPLALPPREPHLLSSLYSTEKLRYPARASHHRIFGASVRPCVPAMLPSFSPAVTAAAMAPPPPKPIPGGYGAPVLGPLRDRLDYFWFQGPEEFFRRRAAQHRSTVFRANIPPTFPFFVGINPRVIAIVDTAAFTALFDPELVDKRDCLIGPYNPSDSFTGGTRVGVYLDTEEPEHERTKAFAMDLLRRSSRVWAPEFLEGVDGMLADIESDLAAGKEGGASFLVPLQRCIFRFLCRSVASADPAAEGLVDRYGLFILDVWLGLQLLPTQKVGAIPQPLEELLLHSFPFPSILAKPGYDLLYRFVAKHGAESVAVGVNDHGMSEKDAINNILFLLGFNAFGGFSVFLPFLILQIGKDAALRARLRDEVRAALDQHDGEVGFASVKGMPLVRSTVYEVLRMNPPVPLQFGRARRDFVLRSHGGEGFSVAGGEMLCGYQPLAMRDPEVFERPEEFVADRFVGAGGEALLRYVYWSNGPETGEPALGNKQCAAKDVVIATACMLVAELFRRYDDFECTGTAFTSLKKRPQPQPSS
The following text describes a protein:
Function:
Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
Subcellular Localization:
Nucleus, nucleolus. Cytoplasm.
Domain:
The truncated protein kinase domain is predicted to be catalytically inactive; has lost the main activatory autophosphorylation site and the conserved key residues involved in phospho-substrate. The C-terminal region (containing the POLO box domain) is sufficient for inducing cell cycle arrest.
Sequence:
MYTVLTGTPPFMASPLSEMYQNIREGHYPEPAHLSANARRLIVHLLAPNPAERPSLDHLLQDDFFTQGFTPDRLPAHSCHSPPIFAIPPPLGRIFRKVGQRLLTQCRPPCPFTPKEASGPGEGGPDPDSMEWDGESSLSAKEVPCLEGPIHLVAQGTLQSDLAGPEGSRRPEVEAALRHLQLCLDVGPPATQDPLGEQQPILWAPKWVDYSSKYGFGYQLLDGGRTGRHPHGPATPRREGTLPTPVPPAGPGLCLLRFLASEHALLLLFSNGMVQVSFSGVPAQLVLSGEGEGLQLTLWEQGSPGTSYSLDVPRSHGCAPTTGQHLHHALRMLQSI
The following text describes a protein:
Function:
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of the antitumor fumiquinazolines that confer a dual-usage capability to defend against phagocytes in the environment and animal hosts. The simplest member is fumiquinazoline F (FQF) with a 6-6-6 tricyclic core derived from anthranilic acid (Ant), tryptophan (Trp), and alanine (Ala). The trimodular NRPS fmqA is responsible for FQF formation. Modules 1, 2 and 3 of fmqA are predicted to activate and load Ant, Trp and Ala, respectively, providing for the assembly of an Ant-Trp-Ala-S-enzyme intermediate that would undergo double cyclization for chain release and generation of the tricyclic 6-6-6 product fumiquinazoline F. The presence of an E domain predicted for module 2 of fmqA is consistent with epimerization of L-Trp to D-Trp during assembly to generate the R-stereocenter at C14 of FQF. The FAD-dependent monooxygenase fmqB and the monomodular NRPS fmqC then maturate FQF to FQA. FmqB oxidizes the 2',3'-double bond of the indole side chain of FQF, and fmqC activates L-Ala as the adenylate, installs it as the pantetheinyl thioester on its carrier protein domain, and acylates the oxidized indole for subsequent intramolecular cyclization to create the 6-5-5-imidazolindolone of FQA. The FAD-linked oxidoreductase fmqD introduces a third layer of scaffold complexity by converting FQA to the spirohemiaminal FQC, presumably by catalyzing the formation of a transient imine within the pyrazinone ring. FQC subsequently converts nonenzymatically to the known cyclic aminal FQD.
Subcellular Localization:
Secreted. Secreted, cell wall. Note=Localizes to the cell wall of the conidia and In to both the cell wall and septa in the hyphae.
Sequence:
MQYIPFLISGLVPVALSKSLFEATSNTRIDGNDIAAIFGPVLTPEAHIFLPSDGDYDDNVMARWSTFNDPSYVATVKPATETDVQAIREYQVSTAASHNITFFATGGGHGVKLNFGNVQNAINIELSLLDFIDLDLDNEVVTIGPGVENAQLYDLLSSVGKETALTGERCVNTIGPTLGGGLGPLYGIRGPQVDSLVSARLVTASGDVITVSRSENRDLFWAIRGAGANFGIVTSATYRIYDQTNGGMAVSAQFAFAPAVNRSVFDLMESMNDEYPPGMSGGMILSYNHTTNEPSVQWNLLFMGSNEDAQPWLDKIQALGPIDSSIRNVPWHRRDEPEVPYCERGQHYILYNLNLRRTDAATLQSYFDSFVDFSSKNPWFDCDLMYERQATDAALAVPLSERGVGPWRDSKINANFLVVTPSEEYDEAADAFVRPFMDRFQAVMGFDTLHVYVNEALGDEGPASWYGEENLPRLVALKQQWDPENKFGAGAPIPLSL
The following text describes a protein:
Function:
Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Acts together with GIF1 for the development of appropriate leaf size and shape through the promotion and/or maintenance of cell proliferation activity in leaf primordia.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to intron retention.
Subcellular Localization:
Nucleus.
Domain:
The QLQ domain and WRC domain may be involved in protein-protein interaction and DNA-binding, respectively.
Sequence:
MMSLSGSSGRTIGRPPFTPTQWEELEHQALIYKYMVSGVPVPPELIFSIRRSLDTSLVSRLLPHQSLGWGCYQMGFGRKPDPEPGRCRRTDGKKWRCSREAYPDSKYCEKHMHRGRNRARKSLDQNQTTTTPLTSPSLSFTNNNNPSPTLSSSSSSNSSSTTYSASSSSMDAYSNSNRFGLGGSSSNTRGYFNSHSLDYPYPSTSPKQQQQTLHHASALSLHQNTNSTSQFNVLASATDHKDFRYFQGIGERVGGVGERTFFPEASRSFQDSPYHHHQQPLATVMNDPYHHCSTDHNKIDHHHTYSSSSSSQHLHHDHDHRQQQCFVLGADMFNKPTRSVLANSSRQDQNQEEDEKDSSESSKKSLHHFFGEDWAQNKNSSDSWLDLSSHSRLDTGS
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MNWSDLNLMPAMPEIVLLSLLVLLLLADLWVSDDKRPWTHYGALATVAVTAVVQLAVWEQGSTSSFNGMYIADGMSRLAKMVLYALTFALFVYAKPYNQVRGIFKGEFYTLSLFALLGMSVMVSAGHFLTAYIGLELLSLALYALIALRRDSGFAAEAALKYFVLGALASGLLLYGISMVYGATGSLEFAGVLASSFNEEANEWLLKLGLVFIVVAVAFKLGAVPFHMWVPDVYHGAPTSVTALVGTAPKIAAVVFTFRILVTGLGTVHHDWSLMFALLAAASLLVGNLAAIMQTNIKRMFAYSTVSHMGFILLAFMAGAVGFAAGLYYAITYALMAAAGFGVLMVLSDGDNECENISDLAGLNQHRVWLAFLMLLVMFSMAGIPPLMGFYAKFGVIMALLKQGHVWLSVFAVIMSLIGAFYYLRVVKVIYFDVPDHDQPVGSNYAAKFVLTVNAFLLLLWGIMPQTVIDWCAKALENTL
The following text describes a protein:
Function:
Component of the get4/get5/sgt2 sorting complex involved in the GET (guided entry of TA proteins) pathway that leads to the insertion of tail-anchored (TA) proteins into the endoplasmic reticulum. Get4 and get5 form an obligate complex that catalyzes the transfer of tail-anchored proteins destined to the endoplasmic reticulum from sgt2 to the cytosolic targeting factor which then targets the TA protein to the ER membrane via get1/get2.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSRIDKTIARQREKIASGAYYEAHQQLRVIAARYIKQSNYEAAAEILAGGATALLRAGSQQGASASGGDLAIMLVDEVYTKAGWGITGGDDDAEGRARKKRLIELLREFPSEEPTRKRFIQEMIGWSGRFGPVERGDAELHHAAGSVYAEDNEPYDAEKHLVLGTSESAETLAKLEYEWYTNDEPHTAAIYASRAVFPYLLVGNLRNANKAFLVFTSRLSSSNTSLGVQEVSSASSDVRVFPSLPLLNFISMLLLTIQRGSADLFKQLTAHYASQIREVGIWDDALSQIGEQYFAIKVPRQGNPLLDMMGSMLFGGQNQGGSRRTPQGRSQSKTVEAPPASMELD
The following text describes a protein:
Function:
Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Acts in the glutathione degradation pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MGTVIEGKLRFCIDRGGTFTDVYAEIPGHSDGHVLKLLSVDPSNYDDAPVEGIRRILEEYTGKKIPRTSKIPTDKIQWIRMGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPDIFDLTVAKPSNLYEEVIEVDERVVLALEDDDDDEGSLIKGVSGEFLRVVKPFDGEGLKPLLKGLLDKGISCLAVVLMHSYTYPKHEMDVEKLALEMGFRHVSLSSALTPMVRAVPRGLTATVDAYLTPVIKEYLSGFISKFDDDLGKVNVLFMQSDGGLAPESRFSGHKAVLSGPAGGVVGYSQTLFGLETEKPLIGFDMGGTSTDVSRYDGSYEQVIETQIAGTIIQAPQLDINTVAAGGGSKLKFQFGAFRVGPDSVGAHPGPVCYRKGGELAVTDANLVLGFVIPDYFPSIFGPNEDQPLDVAATREAFEKLAGQINIYRKSQDPSAKDMSVEEIAMGFVSVANETMCRPIRQLTEMKGHETKNHALACFGGAGPQHACAIARSLGMKEVLVHRYCGILSAYGMGLADVIEDAQEPYSAVYGPESLSEVFRRETVLLREVREKLQEQGFGDGNISTETYLNLRYDGTDTAIMVKGKKTGDGSAFDYAAEFLKLFEQEYGFKLQNRNLLICDVRVRGIGVTSILKPRAVEAAPVTPKVERHYKVYFEGGWHDTPLFKLENLGFGHEILGPAIIMNGNSTVIVEPQCKAIITKYGNIKIEVEPATSSVKLAENVADVVQLSIFNHRFMGIAEQMGRTLQRTSISTNIKERLDFSCALFSPDGGLVANAPHVPVHLGAMSSTVRWQLKHWGENLNEGDVLVTNHPCAGGSHLPDITVITPVFDKGKLVFFVASRGHHAEVGGITPGSMPPFSKAIWEEGAAIKAFKVVEKGVFQEEGIVKLLQFPSSDETTTKIPGTRRIQDNLSDLQAQIAANQRGISLIKELIEQYGLGTVQAYMKYVQLNAEEAVREMLKSVANRVSSETPNSRVGNSVTIEEEDYMDDGSIIHLKLTIDADKGEASFDFTGTSPEVYGNWNAPEAVTSAAVIYCLRCLVNVDIPLNQGCLAPVEIRIPAGSFLSPSEKAAVVGGNVLTSQRVTDVVLTAFQACACSQGCMNNLTFGDDTFGYYETIGGGCGAGPTWNGTSGVQCHMTNTRMTDPEIFEQRYPVLLHRFGLRENSGGNGLHKGGDGLVREIEFRKPVVVSILSERRVHSPRGLNGGQNGLRGANYLITKDKRRIYLGGKNTVHVEAGEILQILTPGGGGFGSNI
The following text describes a protein:
Function:
Glycerophosphocholine glycerophosphodiesterase responsible for the hydrolysis of intracellular glycerophosphocholine into glycerol-phosphate and choline. The choline is used for phosphatidyl-choline synthesis. Required for utilization of glycerophosphocholine as phosphate source. C.albicans can utilize GroPCho through transport and intracellular hydrolysis or through extracellular hydrolysis.
Subcellular Localization:
Cytoplasm.
Sequence:
MKFGKTYVTHQIPEWSIYYMNYKQLKKIIKSIDSAANTNVDESKYPEVISDTLGSFFYDLDRDIEKVDSFYNTKFKEYNRRLNKIFQVLGYQDGQITHNIESSEELDEIINILIELKSLFRNLKWFAELNHKGFIKILKKLDKKLTSILSQHSGVSVGGVSNHNQEAYMGSRINALPFANGTEASNCLDSIHHILSRIETRNDVVQETIPVENNETSISALIKNDDFEGLKKHITIKSSQKFLISTLNKAALANSTKCIDVIWNQLDMLYDDSDFNGRNFFHQHIISLGKAQFIREEQIVPGEVTNRLIGGDNGPDNSNKNDNPIGLLYILNKLKHKRLILAEDHYHRTPLHYASQYGLVEVTRYLVEFGVKWGLINTSISIDDVSIWGDQEGLTPLHLSIIGKHPKTTETLLGFNKAQTLTCPNLLLLAVRLNSPQILNSLIVEGNIDVNYTDIDHRNETALYIASKLNHPDLVEFLLESNANTEIGENVFGWTPIFIAASEGFMTIVKLLKEYGASYDIVDDSGWLPMEHACLRGHLDVTDLLLPKNEKLLLYDMYHPENNLPRIPSLAASPVLTGSDDGTVSTSSIDKLPEPQKNTVNQFYKQLKNNSSNNVSRSTSPKRNKRYKPVKSFGHRYLNEDESLILLTLGTTDLRDTNVPVELNKVSLAKSFATELDTALSLSITCRHKLTNNPVEPPVVVDLPLEDFHGSATDPISFKLSNDLTVNDVIITFDIIPTYQVNKKVIGRAIALLKDAYTKVGPNLRSLNNSIAIPIIESTNLDILGTIRFEYLQVLPFKHKAMSIARSDTYWKQLVSTRVIGHRGLGKNLSGKKSLQLGENTVESFIAAASLGASYVEFDVQLTKDHVPVVYHDFTVAESGVDIPMHLLTLEQFMGFNTPTEKPTHTVDDEVLTRGKQRAQSSYQLSNNHNDDIEKEFANQRDERMKFTKTWKNQGYKGNLRGSSVASNFVTLRELFRKLPNNVGFNIEVKYPMLDEAQLEDMGEIGVDLNFFVDTILKVIYDENTTGRDIVFSSFHPDICLLLSLKQPTMPVLFLTEAGTAPMYDIRASSLQNAVRFSKKWNLLGIVSNALALIKTPRLAQVVKSMGLVCVTYGTENNEPELAKIQMRAGVDAVIVDSVLAVREGLREHNETMNEFEDSPTE
The following text describes a protein:
Function:
Produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MALQIKIVAPNKVVFDDQVDEVVLPSVSGQLGILTNHAPLITGLSNGVMRVRKQGTFIPIAVLTGVAEVDNNEVSVVAMAAELGSGIDVDRARAALARAEQTLATSQNKTELLQAQTALERANARLRAAGAL
The following text describes a protein:
Function:
Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTSRGGSCNDGASSNSNVSNSTNWTKGVKGFLLDVYGVAYNCGQTFSLIDGSVEAVSKLRKAGIPFRFCSNTSTKTPEKVLERLLEFGFDVKPGEIFTPIPVVKNYLRKHGYRPFILVDPCVDQEFAEFDQSDPNCVVLGDAKHRFSYENLNKAFQMLTDKKDSAIITLGTGKYYKETEGMFLDCGVFAKALEFATDKQSVCIGKPSKEFFTAAMNSMGLKPEETVMVGDDIIGDVQGAQQAGLKGVQVRTGKYRQLVDEPHSYVRPDAYVDNLLQAIEIYLAGKI
The following text describes a protein:
Function:
Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.
Miscellaneous:
MISCELLANEOUS: Present with 468 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MLKRLANRQNGFASFSCSSVGLRYGRTNPSTKRSFSLFQSVADTFLTVHEASHIPWIVLVPLTTMTLRTLVTLPFSIWQRRRILKQQELRKLVQPITPIIKLRLAAVTNKKSRNAARISSNGSFMPLQLQNAGVLTPEQITLLAVKETRKRQKKLFKKYNVPLWKNALLPMVQIPLWVTVSMGIRTLTETQLIESFYPSWFSALGFSSFDLSSPLVAMPLLAPILVGTLAVLNVELNGRLMFSSSLSSQGIKTISRNSTRVQEAMTSILNVSRLGCVVMLAMSSQAPFLLSLYWISSQLFSLVQNIILNWIYPYQR
The following text describes a protein:
Function:
Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Subcellular Localization:
Apical cell membrane; Multi-pass membrane protein.
Sequence:
MGAPLPKAEGPWVQLQKLLASWLVREQDWDQHVDEAHMLQQKRIQESPLLQAAKENDLCVLKKLLLDRNCDFRQRGALGETALHIAALYDNLEAAMVLMEAAPELVKEPTLCEPFVGQTALHIAIVNQNVNLVRALLARGASVSARATGTAFRRSPRNLIYFGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGRRDHLQSLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSWGEDVSFLELVVSSKKREARQILEQTPVKQLVSFKWRKYGQRYFYILGALYTLYMICFTTCCIYRPLKFRMGNRTDPRDNTVLQQKLLQEAYVTQQDKIRLVGELVTITGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIIIYACMVLVTMVMRLSNMNGEMVPMSIALVLGWCSVMYFARGFQMLGPFSIMIQKMIFGDLMRFCWLMAVVILGFASAFYVIFQTEDPANLGQFYDYPMALFSTFELFLTVIDGPANYEVNLPFMFGIVYFAFTIIATLLMLNLFIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWPRSGICGCQYGLGDRWFLRVENHHDQNPLRVLRYVEAFKGSDKEDGQEQLSDKQPSVSVTESGTLARASLAPPTPSLSRTTSHSSSHRGWEILRRNTLGHVNLGLDLGEGDGEDNIYHL