lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MMVRYGLRALYYFHSILGLVPYELNNQNGLRRSKCKRQWTLTIGCTTVVLVGFSFCTVWLQDTLSFATFVDALLIRSLVLVEFTIRYGTVVLCFYQLLRHEVSLHRYVQRFVVIGKSVIVRCNSRSYASVQRMVYALVAKMLIADVGLCTLFAMNSGIKRHETSAHVYRTVNIYVVMMSSQFTNLLLLMLLFGSYVYGQINKQLDRTVHRLASFETQQSYWSRRRVRVQQICCDASDTIDRLCTLHQELTEIVRAIVSIFQLPVLLMNLNQFIVIVSRIYFVYILSAQVKHRSDYMSYHRFFNSILYICFEAVQCFLLALGSSVIAQEARRPGTTMNVFVNAWLDTRTERSIELFTLAVLTTDARIKIGGMYVLNMAFVFSLATTVNMYLIVLVQFQLNID
The following text describes a protein:
Function:
Negative regulator of epidermal barrier repair and innate immune responses to wounding. The role in epidermal tissue integrity and wound healing is established through the inhibition of epidermal microtubule stability, possibly via the negative regulation of the microtubule minus-end binding protein ptrn-1. In epidermis, prevents expression of specific unc-44 isoforms probably by promoting nuclear localization of pinn-1, which in turn may affect sydn-1-ssup-72-mediated regulation of alternative polyadenylation of unc-44 mRNA. Appears to act downstream of or in parallel to muscarinic signaling in the regulation of autophagy.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Note=Exhibits movement along microtubules.
Sequence:
MSDDVNSSATSTSSSTVHFDDTPFEDVYEIETELGSGQFAVVRRVRDRKTGEKYAAKFIKKRRYATSRRGVTRQNIEREVRVLQKIRGNSNVVELHAVYETASDVIIVLELVSGGELFDHVCAKECLDEVEAAAFIKQILLAVRHLHSLHIVHLDIKPENVMLKQRGDSQIKIIDFGLSREIEPGAVVKDMVGTPEFVAPEVVNYEALSPATDMWAVGVVTYILLSGGSPFLGDNRDETFSNITRVRYHFSDRYFKNTSKHAKDFIYRLFVRDVDQRATVEECLQHPWIRGPEGNAIDIRKASCITISHIQSFKTRQRWKRCVELVMVLLKASKSSRRIGDGRFDEEDMVASCTLICAEEGNLRALHKLSALHKLLPNATRKSLKSSFSEPNGATAMHCAAKYGHAEVFNYFHMKGGNICARDDNGDTPLHVACRFAQHTVAGYVANEKIDVDSINKTGETALHCAVESADTRVVRLLLQLRPRLDLPNASGDTVLHLAADSINPRIVPLLVCLAPPLHLRNIREETPLHVAAARGHVDCVQALLDANSPIDAVEQDGKTALIIALENGNVDIASILITNGCDINHADHHGDTALHIASKHGLLQAVQTLCHCAVTVDSVNANKKTALHLAAHYGHVDIIRVLLLARADVTLRGDDGLTAELVAVAAERLEAHSLLKMVKSQEIREEYISQLYPLDTSLRRIKLKLLGHSQSGKTRLVQTLHSSRGISSFLESVTRRISDHYSPSSSMKDDGIHSTNGSFVSESNNNSSFDLAAAAGSKYAPPHSQYTRGIDVQTVNINGCGEFSVWEFGGYEPMHTCYDHFVGNADCIHLILYRTSDPTEVQYKQILYWMNFLKGRVTPFEPIGHCGFSSRRSKVIIVGTHATSSLFPQMNQEGEYVSSDIEAMLNTVRLRFETHFDMDHRLILLDATNPSCIGMKTLKMELAKCRTNILAKLLKPLAILDTVVNHLNLVRKKHANFPVITWPDFIQLVRNEINPLTGDAHCRQIVQQLQLIGELVYLRNDLCDADYVVLNAEWFGTHILGQLLSAEFLSKASPNGSYHTSSLAKIFPEIPEQSDLMTILEVLQLCAPDARTGAHEFPVFIQTEAPDSIWRPYSLKEKERDTVYGGVRILPMRGMERSLHSTFPRIQVALRRSINDYQPAKDTQLHQWSECSKLVSQDREAVIRMVGDAVEIRARGPSESATSMFYFMEDLINLVEHAAAEVGPGISLERHFISPKHLKEHREHPALFPPESMMEMQQRESLSVKGTQDEEELFTDVVCFGSRDVARHLTLGIDVGVADLQMASRCELACLLDPPHAMGRDWSILAVKLQLTDQVPDVDSTGQSLSRTDQLLNEWAIHHPEQASVGNLCRILVELGRCDARDALYRTVPLYVFAPLEDQFLLETNDSGVVSSCHSSSEHNPINI
The following text describes a protein:
Function:
Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to proteins with a C-terminal sequence motif -XCC or -XCXC, where both cysteines may become modified.
Sequence:
MHGVLKVRTSEEKAKAQRLKELEKIESYNKLVKSFEELREKQNGRYDEISLSVSKLVLIENPEFYTIWNYRRLAILQFTETKENSELQVIYQNEMKFLEECIQRFTKSYWIWFHRQWIALRMDNCDWEREMKLCTKLLNFDLRNFHCWGHRRFILKHSNIKLEDELKYTTEKVEQNFSNYSAWHQRSSILPKIYKEPEQLLEKILEEFELVRNAVYTEPKDSSSWIYHKWLVATIKSIPNSNYIEVLKNELTQIYDLIELEPDCKWPIYTTLLLKIEIGGFEKQELLDIISQLIKLDPDHKNYYKSLETKI
The following text describes a protein:
Function:
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
Subcellular Localization:
Secreted.
Sequence:
MTRWALLTLMVLTLGRTLLVPATPTPGFQLLPQNFPQATACPVTSESPSGSTTAPSAAWGRPSPDPHPGPRITLSLDVPLGLLQILLEQARARAVREQAAANARILAQVGRR
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC46.
Sequence:
MTPTACATVSTMTSVGVRALRQRASELLRRVEAGETIEITDRGRPVALLSPLPQGGPYEQLLASGEIERATLDVVDLPEPLDLDAGVELPSVTLARLREHER
The following text describes a protein:
Function:
Serine/threonine-protein kinase required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I (By similarity). Required for pollen development and germination, probably via the modulation of phosphatidylinositol 3-phosphate (PI3P) formation and vacuolar organization.
Subcellular Localization:
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Endosome membrane; Lipid-anchor.
Sequence:
MGNKIARTTQVSATEYYLHDLPSSYNLVLKEVLGRGRFLKSIQCKHDEGLVVVKVYFKRGDSIDLREYERRLVKIKDVFLSLEHPHVWPFQFWQETDKAAYLVRQYFYSNLHDRLSTRPFLSLVEKKWLAFQLLLAVKQCHEKDICHGDIKCENVLLTSWNWLYLADFASFKPTYIPYDDPSDFSFFFDTRGQRLCYLAPERFYEHGGETQVAQDAPLKPSMDIFAVGCVIAELFLEGQPLFELAQLLAYRRGQHDPSQHLEKIPDPGIRKMILHMIQLEPEARLSAEDYLQNYVGVVFPNYFSPFLHTLYCCWNPLPSDMRVATCQGIFQEILKKMMENKSGDEIGVDSPVTSNPMNASTVQETFANHKLNSSKDLIRNTVNSKDEIFYSISDALKKNRHPFLKKITMDDLGTLMSLYDSRSDTYGTPFLPVEGNMRCEGMVLIASMLCSCIRNIKLPHLRREAILLLRSCSLYIDDDDRLQRVLPYVVALLSDPTAIVRCAAMETLCDILPLVRDFPPSDAKIFPEYIFPMLSMLPEDTEESVRICYASNIAKLALTAYGFLIHSFQLSDVGVLNELNSQQISTTPASETPSHLQKANGNAQLQQLRKTIAEVVQELVMGPKQTPNVRRALLQDIGELCFFFGQRQSNDFLLPILPAFLNDRDEQLRSVFFEKIVYVCFFVGQRSVEEYLLPYIDQALSDQTEAVIVNALECLSTLCKSSFLRKRALLQMIECVYPLLCYPSQWVRRAVVTFIAASSECLGAVDSYAFIAPVIRSYLSRLPASIASEEGLLSCLKPPVTREVVYRIFEKTRNPEFMAKQRKMWYSSSPQSKDWESVDLFDKDAGELNSVECRAEQKQSVEGKKQIKSASKQPEVQGKYAEKDAKLRIPRNPRPNASNTVELRDPVYPEKLQFSGFMAPYVSGANSFIEPENIPLYSFSMDKRAATNPPVASESSLQMNSLGMGSLSVPWMDSMSKSFNLASSVPVPKLISGSFHVGTNPKQFYRVVHEPESRENDQISSAISKFQDLGVSSSSKSASVTSEDASSPADLVGEPSLSRTSVPDSGWKPRGVLVAHLQEHRSAVNDIATSSDHSFFVSASDDSTVKVWDSRKLEKDISFRSRLTYHLEGSRGMCTTMLRNSTQVVVGASDGVIHMFSIDHISRGLGNVVEKYSGIVDIKKKDVKEGALVSLLNYTADSLSGPMVMYSTQNCGIHLWDTRSDLDAWTLKANPEEGYVSSLVTSPCGNWFVSGSSRGVLTLWDLRFRVPVNSWQYPIICPIEKMCLCFLPPSVSVSTTMKPLIYVAAGCNEVSLWNAEGGSCHQVLRVANYENETDVSEFQWKLPSNKVNPKPNHRQNMSSKYRIEELNEPPPRLPGIRSLLPLPGGDLLTGGTDLKIRRWDYSSPERSYCICGPSLKGVGNDDFYELKTNTGVQFVQETKRRPLATKLTAKAVLAAAATDTAGCHRDSVQSLASVKLNQRLLISSSRDGAIKVWK
The following text describes a protein:
Function:
Endonuclease which binds to the 3'UTR of target mRNAs and induces degradation of the transcript. Acts together with rle-1 to repress the expression of the transcription factor ets-4 by binding to the conserved ADE (alternate decay element) and RCE (REGE-1 cleavage element) stem loop structure in its 3'UTR, which controls the expression of genes in the IIS and TORC1 pathways, including those involved in lipid metabolism and autophagosome formation. May play a role in the clearance of apoptotic cell corpses.
Subcellular Localization:
Cytoplasm.
Sequence:
MDSTARGHAPLCRTSNQRGLGTRLNPYYQSTPHQPMVQSMSNPIGSYGEQGNAQIIGSSGQVLSTGPPPGLAPVQCNDFDSCYSSCDDISHPSLSRESSDPSKIDDDQTAPMIRYPAPEVVEFATKLGYSTEQLSHVLNTIGVDSRMDDVLSELVKMGLPGGKPENSGKSGSRNSPEPIMTSSASSSSASSSSSHRPIRQSVSIATSSPATSSSTPSKYNPDPSLRAVVVDGSNVAMLHGRKEVFSCAGLRECLNYFLERGHPEVLIFIPQYRREQPRSDSPITDQHILQEIERHIIYTPSRNVNGRRVVCHDDRYILRTAELKDAVIVSNDEYRDLTRENPAWRKIVEERLLMFTFVEDKFMPPDDPSGRHGPRIESFLSKVPVVSSNPLVCPYARKCTYGNKCKFYHPERANGQHMSVTERLMKENQQKKSLGAVKSMQYEMFKNKHAALSRTQSLNVVKQLTENMSQLPPTPESPMQMPRQHMQLQQANSAPWQQHTVVQRHGSSPLTPVNRQMNVYPDMYNMSQQQNHQVLPNQHGVIGGQRPPKMTTTVSQTHLFAPSTAVWGHSELSVGPVNTGSDESLAEVRSRVHFHLCNIFPHDFVESVMAANPEEVNAPVLCELIIRAQKEYRK
The following text describes a protein:
Function:
Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.
Subcellular Localization:
Nucleus.
Sequence:
MVTRLPRKQQSGAAGDVVQDAAWNSTDLRKAPRDMNRIPGSTASMTVQERKKDARASTDSSTSSAAWSSQLATSSTLRGKTAIQAMQPFLDSSTTSSSPIQPTDIQLLTKSILSNQERQRVILYYQEQLIHSEPSLSELKKSLLFLSSSSWGQILEERKLAEKCSYPRCSNASPSRSGATNGRFRINLRNKSVKAIQDLDLGEAGNTWDDLKEMFCSKKCYARSEWILRWVLGECEIGLEKRDAQDRGARGGGGVLGGKWQKLTSQGGYEQVELLEDIERESGLKLEAGEMFVDRVLDSEPLKQEVAAKTMRQGALEPQSTGAACQVTNLLQDLTIVERRKDSTCATPGASACTNSTNSTASHTSQSTPTSKTAYDVDVPNTLGSRFTRNCTDKDERTDDDTHPSFEQRQREISHILRYASLAKASRLVLDRGMDSTSGAVDDAHLSVDTRDRSDDQEHTPVLDAQAAAERAHLRRIMDDALDVRRDQRELGLLD
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.
Subcellular Localization:
Mitochondrion inner membrane; Lipid-anchor; Intermembrane side. Cytoplasm. Nucleus. Mitochondrion.
Sequence:
MGGTASTRRVTFEADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSSVYGASVSDEDLKRRVAEELALEQAKKESEHQRRLKQARDLERERAAANEQLTRAVLRERISSEEERMKAKHLARQLEEKDRVMRKQDAFYKEQLARLEERSSEFYKVTTEEYQKAAEEVEAKFKRYEYHPVCADLQTKILQCYRQNTQQTLSCSALASQYMHCVNHAKQSMLEKGG
The following text describes a protein:
Function:
DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Subcellular Localization:
Nucleus.
Sequence:
MSENKENYVLYQEQMMKTYEQINEKWKALSYKKAIISLKKHPAKISTFEEAKSLSGVGEKLAEKIWEIVESGKLRKLDELSETEEVTSLNTFVNVWGAGPKTAQTWFAQGFRSLKDLEEKAQLTRCQKIGLKYYDELIERMERAEVQKIESVVLTEVNILRPGCELVVCGSYRRGQTTCGDVDILITHPDGSSHVGLFDALIGSLTETGFLTDELIIAHNGPQQKYLGLCKLPESKHRRIDIIVTPHNEFYTALVYFTGSGHFNRSMRHMASKMNMSLNEHGLYTGVTRNNGVKVCSGSSLPITSEESIFKYLGVPFRPPEERDY
The following text describes a protein:
Function:
Odorant receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQGLNHTSVSEFILVGFSAFPHLQLMLFLLFLLMYLFTLLGNLLIMATVWSERSLHMPMYLFLCALSITEILYTVAIIPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSLRGCTCRVGCSWAGGLVMGMVVTSAIFHLAFCGHKEIHHFFCHVPPLLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKAFSTCASHLTVVVVHYGFASVIYLKPKGPQSPEGDTLMGITYTVLTPFLSPIIFSLRNKELKVAMKKTCFTKLFPQNC
The following text describes a protein:
Function:
G-protein coupled receptor. Plays a role in plants and microbes interactions (By similarity).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRVLDEIAESPFLISPLNPNSTANGYRWVDKCHGFLHNTVLVAASLFFVAYLAYEAKKSLSKLSNRRSYIMIAYYGCLWLVSLLNLAWCCLQGWECTPGKEVVWNLLTLFTTSGMLFLEVSLVAFLFQGNYASGAEALTRTFLISGFIVALDLLLKAIFLFGFGVPLFIDNNENGKTFKWGLWIIHKLLLTGVYGMVFLMYNSRWREKLPARPAFYNYIIIMFALYSLYLVASAFTANNAHFGFWLYGIMSVCYHALYLPLLYITFLADFFQEEDLNLENVYYSEMKDAGFFDSDWE
The following text describes a protein:
Function:
Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.
Subcellular Localization:
Mitochondrion. Mitochondrion outer membrane. Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Note=Localized to specific membrane structures termed mitochondria-associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria. Also associated with the outer surface of mitochondria at sites that are not in close contact with the ER.
Sequence:
MAGGPPNTKAEMEMSLAEELNHGRQGENQEHLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAKRVWNMTATRPKKMGSQLPKPRMLRESGHGDAHLQEYAGNFQGIRFHYDRNPGTDAVAQTSLEEFNVLEMEVMRRQLYAVNRRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMNQ
The following text describes a protein:
Function:
Involved in the maturation of [NiFe] hydrogenases. Involved in the biosynthesis of the Fe(CN)(2)CO cofactor. HybG delivers iron-bound CO(2) to HypD where reduction to CO probably occurs. In complex with HypD, accepts the cyanide ligand generated by HypF and HypE, and also coordinates the carbon monoxide ligand (By similarity). Involved in the maturation of the hydrogenase 2. Also participates in the maturation of hydrogenase 1.
Sequence:
MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA
The following text describes a protein:
Function:
Thioesterase that may be involved in phospholipid metabolism. Displays acyl-CoA thioesterase activity with lauroyl-CoA (C12:0), myristoyl-CoA (C14:0), palmitoyl-CoA (C16:0), stearoyl-CoA (C18:0) and benzoyl-CoA, catalyzing the hydrolysis of the thioester bond. Has low activity with butyryl-CoA and octanoyl-CoA.
Sequence:
MRCRVYYEDTDSEGVVYHANYLKYCERARSEFFFKQNVLPENEEGVFVIRSIKADFFTPASLGQVLEIRTQIKELRKVFVVLFQEIYCIQNASLEPMKPFKVFASEIKFGFVNRSTYSPIAIPKLFKELLNAI
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MPKSDFERLAEWRTLGARHSEETVQLAKRVLLSGNAGDQEWAIREQLAIAALDLGQTLLASEQIETLYGKFPGSPRVRILDGLKFEADGDVSRARAVYEALLKEDETNITAHQRIISLALPSLSAIPLLLSYLDVFYSDPAAWSLLADLYSEQGLYSQALGALGHLSVINSWDDGVVRRCGEVAYTLGDYHLALKHFLRASEMQGGKETNVNTRRTRTWWGIKLAIQRLLDSPNLETSVPADLQTSEKHLRLLDELATERLLDAGGQGLDVRRKVLGEKALRR
The following text describes a protein:
Function:
Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVILISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATVLEIGSLFLIYKWSYGEPLIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCIVVGLYPTLLMTLIGVLWFPSRAISQMHQALNDRLDDAISHLTDSLAPLPETRIEREALALQKLNVFCLADDANWRTQNAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKLASEINKLQHAVAEGQCWQSDWRISESEAMAARECNLENICQTLLQLGQMDPNTPPTPAAKPPSMAADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVGSSYQKMVLRFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERSSYIGTQMVVTFALATLENVFGPVYDLVEIRDRALGIIIGTVVSAVIYTFVWPESEARTLPQKLAGTLGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVALERQLDSEERALLIERSQTVIRQGRDLLHAWDATWNSAQALDNALQPDRAGQFADALEKYAAGLATALSRSPQITLEETPASQAILPTLLKQEQHVCQLFARLPDWTAPALTPATEQAQGATQ
The following text describes a protein:
Function:
Required for chromosome condensation and partitioning.
Subcellular Localization:
Cytoplasm.
Domain:
Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
Sequence:
MRIKWIELNGFKSFPERTKIELNEGITCFVGPNGAGKSNIIDAFRWVLGEHNPRILRGEKMEEVIFQGTFSKKEKGLAEVTLLLNIKKESTNGNDPETQEIEVKRRLYRTGESYFSINGKQSRLKDIKEIFISEGVDIRTYSIIDQIKINEILFKPSQRKSLLEECAGISLYKLKKTESETKLQSAKENLQRIEDILNELKKQYSLLERQAKKADKYRKVMEELKDAELKVSKTEILNLLGELQKLKNEIENLENKQSKLKEENGKIIEKINHQKKYIAEIEVTIQERDNQIKQGELEKAKIEKELALLAQEELNKKEQIKKLDEENTSIHDEIEKAQQELKNCHIQSQEIEEFIDLIQKEIISEEENLLTLQKEIVEIEKLIEKERKTLFSLTTELANKRNNYQSIKKSLEQVQNRISNIEVRKKEIYQKIRQMETEVKNREIKIKSLKEDYQEEIYKINILKQQLSEAEGLFESQSQILLEKKKIEAIINGKIEALSSEIWEENSNHKLFFECIDVSPEVEELVEIFLDDKLKASIIDKIEEIERVQHKKFFFLKNNDQTTAESPNLPGIKKIKDFLQIKDSEISGEIFENLFIVNSLKEALEKRRAYPQCSFITTKGEVIFSDGFIKVGRPTDLLKKKRMLEDLKAEKNKLTDDIKSIEEEINRIRAKREELKKEIEEKRAYITQLNKEIFQTEERYKTFLKDIEQTKQRLKYMENEEKTIRDEINQNTKLKEEVYVEIQNLSLCIEELEAKIEELKNEQKEILNKNDIHKEAVSNKKIELSTLKEKLNSKKIEIKRLNEHLKTISIKKLKNEEEIEQNKKRINQIEYEKAERIKNLENLNLEINSLKEQRESLLEKLQNEKSVLTELEKSYQRLNEELQSITALLGEKKTIEGEGKIKLENIWNEIYNLYGVDIIKEEFETVQEIEQLKIRITQLKNQLRDIGPVDVDILREYEEVRERYEFLLNQQEDIKTSIKELEEAIRKINSLTRRKLKETFDLLKDKFNNTFQELFGGGKAEIILTDEINILDSEIDIFVQPPGKKSNSINLLSGGEKTLAAIAFVFACLSIRPSPICIFDEIDAPLDDPNILRFRKLIKDLSSKTQFLIITHNKLMMECADYIYGITMQEEGVSTVISLGLKEAEVYA
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase.
Sequence:
MSKEDIPSSNEGTVAVEDISSLTIQGPESSVATDRPELPHRSHNPENNMKRSDPFQFGSRYLGEQDNVFEFNAWDHVETDDTYKEYAELQYAKQREAPVSEFDKNRFNSDPAKWWNNFYKNNTANFFKDRKWLQQEFPILSQVTESNYGPVTILEVGAGAGNTAYPILKHNQNPELKIHACDFSKKAVEVIRANEAYDTKNIQADVWDAAGDDLPPGLKESSVDVVIMIFIFSALSPSQWNRAVQNIFKVLKPGGDVLFRDYGRGDLAQVRFKKGRYLEENFYIRGDGTRVYFFEKDELVNIWTGKLPESDAEGKASEIEQECGFDIIDLGVDRRLLVNRAKELKMYRCWMQGRFKKKSLPITNSK
The following text describes a protein:
Function:
Acts as an atypical protein-lysine deacetylase in vitro. Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues. Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo. Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate. May activate transcription.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDPASLWPQEGAPEHGPVPAPAGWGPASSPTIPPPAPIRRQYASASRLRESTQLPRPFTSTAAAGMAASVEQHEGTIQVQGQALFFREARPSSGQAHFSVLLLHGIRFSSETWQNLGTLHRLAQAGYQAVAIDLPGLGHSKEAAAPVPIGELAPGSFLAAVVDALELGPPVVISPSLSGMYSLPFLTAPGSQLRGYVPVAPICTDKINAANYASVKTPALIVYGDQDPMGQSSFEHLKQLPNHRVLIMKGAGHPCYLDKPEEWHTGLLDFLQGLQ
The following text describes a protein:
Function:
Involved in the lipid remodeling steps of GPI-anchor maturation.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MRMLRGYLELRGTILFRLPLLLLLVSVGRTRASSGDRSEDFSGCLANCRASGCAFLSAQATKGAKGSTCIPDCIPPASGEAGEGGAESKLLTTAWELRALRWTCNSECKYQCMVQREAAKTGAAPEKYYGKWPFKRVLGAQEPASLLLSLLNLLAHAYGLLSLRRTVARLPLVEGRAAYPYTGLWHLYAIFNINAWLWSAVFHARDCKVTEQLDYYSAVALLGFSLIVALIRALGLRTEAAQVTVSAPIIGFTTTHIFALMTFIDDYSWNMKVCLTMGALQLGTWAIWGVRSRHPSLLKLLVAILGVAGATALEVFDFPPYFGVFDAHSLWHAATVPLVLLWWSWVNDDARYVAQKALKGKDVAEKGKTS
The following text describes a protein:
Function:
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gim-1/gpi14 (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Sequence:
MRERITFIQKQGDSIEPTTLKIKGGVLNGPEIQAAREDRLTIAIDELPKDLQALLGTAHELHIRYVSSQPYEAITPLLARLPPGFHLFYTPAGQADATSPALCLALNQIFGNVQCENPEKSFTTLPRDRFSHSAAYQFYQPSVDLSPFIALVKEKLCSSSKDQSCAARADRLANASSLDISYDAISHAVKLTATWPYQKQEVHATSRPQTRTEVGVLNSDRPGHLEPHELGISGLLTVLGQDKKPSATMFAFASRHRDAESSFSAEFLEPTGLHPTLKLRLESSKPPIEDAYCSPHAYFTLPKTIFADRHQLSDDLFLASKNLTGLRYISQPVDLEAPEYVEKRWGSSLLLELSPPEHEESKSWTVQVPLHLRYLSPAEGGYTDIQVPYPAVFWACAAEEGTKFPNNPFEKANLGYDGLFGPRTVFWHVEPRPTIGSRLSNMIKVPVLDTNKAEWVSGGTGLAVLLGFAWIMWKLFGVLSKSGYQNQPSQAAEVVKAKKNQ
The following text describes a protein:
Function:
Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating topbp1- and cdk2-dependent recruitment of cdc45l onto replication origins.
Subcellular Localization:
Nucleus. Note=Associates with chromatin during pre-replication complex (pre-RC) formation following interaction with topbp1.
Sequence:
MNTILTCQDEYFAGGLGYDCPYFSSTSASTVDVSKETWVSLWASGLLDNRSSNHGPHTQGQLYNMGNSLQEDYLFGDQLSSQISANKQLQDTLLQKEEELSRLHEENNKLKEFLNSAFVKTLAEKTKKLLHQNGQSSFCTNPNSRVPFSSNSTPGSKAKRARRNLYGELTACEAQSSPVVEKWVLQTLGLKDVDTIDDSALANYSAMSLQPKQDSPSSGYSSAHLTPGHSQAATSCSLSPSQCSSASLPESETASPLSSPTYHTPDVAPNKTEVAFSTSLHPHCNVKTHSFPQGQAFVRRDTQGGWKFTWVPKQSE
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes; Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Sequence:
MSASKYRQEMPPPGGYGMVDWAKKIPRKGMGGYAIFGAFFAVTTAGWVGYYFERKIKNKQRLEMNDARLAVAPLFVAEEQRMYLKRLRENRDEENELMKDVPGWETGKFEGQPVYHSSHERFPYVDMKEYYAHSKYSDMFDRVYFMRKL
The following text describes a protein:
Function:
Deubiquitinase involved in peroxisome import by mediating deubiquitination of the peroxisomal import receptor PEX5. Catalyzes deubiquitination of both monoubiquitiated and polyubiquitinated forms of PEX5 following its retrotranslocation into the cytosol, resetting PEX5 for a subsequent import cycle.
Miscellaneous:
MISCELLANEOUS: Present with 2810 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytosol. Peroxisome.
Sequence:
MSSEDELGSIGTVFPGSPIDKSIGSILPQFDEEVETLLEDSFTWNIPDWNELTNPKYNSPRFRIGDFEWDILLFPQGNHNKGVAVYLEPHPEEKLDETTGEMVPVDPDWYCCAQFAIGISRPGNGDTINLINKSHHRFNALDTDWGFANLIDLNNLKHPSKGRPLSFLNEGTLNITAYVRILKDPTGVLWHNFLNYDSKKVTGYVGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNNSVPLALQRAFYQLQVSDIPLDTLELTRSFGWDTAESFTQHDVQELNRILMDRLENNMKGTPVEGKLNEIFVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMNGENQYAAQDYGLQDAQKGVIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSGDISTGHYYTLIKPGVEDQWYRFDDERVWRVTKKQVFQENFGCDRLPDEKVRTMTRGEYQNYIIQRHTSAYMLVYIRQEQEEDLLRPVLESDVPKHVITRVREEIKERETKEKEIREAHLYVTLRLHSIKEFIHYEGFDYFAHDGFRLFAEELNDSGLQQINLKVLRTTKLSDIFASIKETMNIPQERDVKYWKMDYRRNSTLRLTQPINFESVNITLQEALKKEKKRTMQTQYGEEGVASTEEDDKALLETVSFLDLFIEEPYLELQFLNKLKEASLISKAQLDDELISTIRTNLPELTKGGIEPVFATDNKSNLLFVKSYDPHTQKLLGFGHFAVNQLQQLSDISAIIEDSISSNEKLTFYEEVQPGTINEIYMKETIYDADIDTGDIVSFEVPGAVLPDTFPVYATIKDFYSYLRYRVKLKFSKFDGSSEEYGVSNEIPESFEFWISAYAPYDDLARMVSKYAHVKPEYLKIIALYSNGRFVLKSTSLLNDYLLKDFNCDQIPPFAFEVLSVPLKELERLRPIKLYWLKNSYIHYQCFEFEVANDYTESQFLEKVQHKIGFTDEEKENILLWTNTNFQFQGLLSDQNTFKDVSKHSLLFGRILPEESKLFKELNRLENVQTSSLEDFMDDENATDRPMDDEQDLGMAIEHSEDMKGRIVVVQQYFKDLENRHGISFLFNLIPDETFPKTKDRLHAKFGLGQKEFSKIKLSIGYSTEEGTVFRSLQGFSDEELDKVILYDIMSNLDYIYMDHPDRLRSHSSYDRPMIIKN
The following text describes a protein:
Function:
Voltage-dependent rectifying anion channel that facilitates the translocation between chloroplast and cytoplasm of phosphorylated carbohydrates such as triosephosphate, 3-phosphoglycerate and inorganic phosphate (Pi) depending of ATP to triosephosphate ratio in the plastidial intermembrane space; in high triosephosphate/ATP conditions (e.g. photosynthesis), export of triosphosphate from chloroplast (outward rectifying channels), but in high ATP/triosephosphate conditions (e.g. dark phase), import of phosphosolutes (inward rectifying channels).
Subcellular Localization:
Plastid, etioplast membrane; Multi-pass membrane protein. Plastid, chloroplast outer membrane; Multi-pass membrane protein. Note=Present in non-green root plastids.
Sequence:
METSLRYGGDSKALKIHAKEKLRIDTNTFFQVRGGLDTKTGQPSSGSALIRHFYPNFSATLGVGVRYDKQDSVGVRYAKNDKLRYTVLAKKTFPVTNDGLVNFKIKGGCDVDQDFKEWKSRGGAEFSWNVFNFQKDQDVRLRIGYEAFEQVPYLQIRENNWTFNADYKGRWNVRYDL
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
Subcellular Localization:
Nucleus.
Sequence:
MSAEKYLDPPHFIQEWESNDESTWPKPPACLGDDETYFSFNRTVKREETDLFPSEILDRTKDVRDQLKQLNHSILVAYLAIISKQMNQPHRYEVITPYVYHLRLLISTMHQALNSYRPYQAKKYYALLFEKQVEHKEKLYEQLKALIDDANNKYKKNFEIPKKSMEEC