lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MEEGQLEASNLPANIWHSEVTVSVTGEPPSAVEEEKETAEETEKEKEVLPEIVEPLSILDVLRISAVLEDTADQLSILNYIMPVQYERKQSVIMKKNKSLEKLAEAPRTSRLSSPFLPKEESKLPEIKKGSQFTDEFNKLQDLVFKKLTRQTIMSTEILKKIQIDRQFFSDIITKTMQELEESGTFTSLLEALGKERENKMHFYDIIAREEKGKKQIKSLQKHLFTVKKERQAEIQSRNEYIAHLKDQLQEMKAKTNMENRYMKRNTDLQISQTQKKCNRTEELLLEEIEKLRLKTEEENRIHMEIETFLKKEQQKLEEKLEFWMEKFDKDTEMKQNELNALKSAKASDLAHLQELAKTIREYEQVIIEDRTEKETTRKKIEQEDLELKSIIKLQAWWRGTMVRREIGGFKMPKKDKDDVKDSKGKGKDKNKRTGKKK
The following text describes a protein:
Function:
Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. Promotes clustering of HT2RC at the cell surface.
Subcellular Localization:
Apical cell membrane. Cell junction, tight junction. Cell projection, dendrite. Postsynaptic density. Synapse, synaptosome.
Sequence:
MIETIDTQRALQAVERLQAKLKERGDVLTEEKLNMLKTVLQSPLFQQILTLQTSVQQLKEQVDAGPASLSPNTELPQTIKPGLCSLPLSDSYVLAQQNGNYGIQRDTPALSITPQINGKPSVDEFEHLIRSMAQGRYVMHIELVKPISGGLGFSVVGLKSENRGELGIFVQEIQPGSVTHCDGKLKEGDQILSINGQPLDQTITHQEAISILQKASEKVNLIVARGPIPQLASPVVSRTPSAASTLSAHSSATHWQHMETIELVNDGTGLGFGIVGGKSTGVIVKTILQGGVADQDGRLRSGDHILKIGDTDLHGMGSEQVAQVLRQCGNRVKLVITRGAIEDSSAPPAPVLPPVVELQCEMTDYEEDDIDAFDVELTKNAQGLGITIAGYVGDKTSEPSGIFVKSITKGSAVEQDGRIHIGDQIIAVDGTNIQGFTNQQAVEVLRHTGQTVHLKLMRRGFRPEEPLISEHKPLPKVVKELAVDRMDSDITIEDSDRKQKPYPSICGSSSITPTEDEQIQSKEGTLLTAVEEEELKKKWQSLLGPSNEVVVAQVEKFSESSGLGISLEASSGHHYIRSVLPEGPVGRSGRLFSGDELLEVNGISLIGENHKEVISILKELPVFVTLVCCRPALLLDSDSDIGGKNGLQEHFDEPEQKVHLDLGDCVGSSETDDIVKENVTEETLGSSLAMWETEIQDIELEKGDMGLGFSILDYQDPVDPEKTVIVIRSLVPDGVAEVDGRLLPGDRLMFVNDTNLENASLEDAVQALKGAPVGKVRIGVAKPLPPTPEEGCSSAKDDSIFYTAQQFEDEEQADAAVFHAELAMIDSNEADLTDEKTFDSQYPGEEDDTFQESMLALHGSTCSVDLDYQLSMHSSTPKSTYEDAFAKPSFSAATEFADEAEPFFPEEKRITLFQPWKATSSALPFGATNKTPSPEQHINLMETDCVMPEVVQSEPCSALNHDKRSIQSFETEMELDKASDACAEYKPCHEGSVSTDPGREDTDDRSSHQEGFVPVKRNEDMEDQGLVENIDNEMFSSGSSFERTITVVKGNSSLGMTVSAVKDGSGMIIRSIIHGGSISRDGRLAVGDCILAINGEPTTNLTNAQARAMLRRHSLIGPDIRSSCAPADDQSPFYVITYVPSEYLEEYRISLVHLKDETTSGAPSTCAEAGELPEREDGEGEESEMQSSAYSNWNQPRKVELFREAGKSLGISIVGGRGMGSRLNNGEVMRGIFIKHILEDSPAGRNGTLKTGDRIVEVDGIDLRDASHEQAVEAIRKAGNPVVFMVQSIVHRPRPDSFYSPSSSPVIEKHITTMPLPHQLCKKPPLPFLLPKPIPEPAFSSTNPFVASFQPSLFQTMTTESNEEKCIPTSNVIAKHEIKIKGSESHSRLFLRLSPTNPFAPTPFKAPSNRLDLEAGKVSLSVPLVSSLPVVPPIGETETDTLMEPENLALPMDSPDEEEDEFGYSWKKIIQRYGSLPGVLHMIELEKGKTGLGLSLAGNKDRSRMSVFVVGIDPSGAAGRDGRILVGDELLEINGQILYGRSHQNASSIIKSAPSKVKIIFIRNTDALNQMAAGPVKECGDMLESQTELDMCAVSPSAIDFDLFKNIQHIILPKDQGGLGIAISEEDTSGGVVIKSLTDNGAAGKDGRIKVNDKILAVDDETVVGCPVEKVINLLKRSKSTVKLTICSEDLSSLSSCVNLPESASDVKISQSLPTAFISDVDPFKNASRSSTPATMASDPVTCPIIPGCETTIDISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAASKDGRLWAGDQILEVNGIDLRNATHDEAINVLRQTPQKVRLTVYRDEAQYKEDDMWDVFFLELQKKPGEGLGLSIVGKRNDTGVFVSDIVKGGIADTDGRLMQGDQILSVNGEDVRSATQESVAALLKCCIGTITLEVGRYKAGPFHSERRLSHSSQVSETGSFGASSCLSGSGSGLGDNFESRRKSLDSGSDFQELRTVEFTKGPLDSLGISIAGGVGSPLGDIPIFIAMMHPTGLAAQTQKLKIGDRIVSICGTSTEGMSHSQAVTLLKNASGTIGLQVCAGGDASVTGSSHEQTASLSLSGLTASSIFHDDLGPPQYKTITLDRGHDGLGFSIVGGFGSPHGDLPIYVKTVFVKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVNLTVLS
The following text describes a protein:
Function:
Has a role in spermatogenesis and oogenesis. Might have a role in triglyceride homeostasis. Probably by regulating lipid storage and catabolism, plays a role in neuronal function.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MIRIRFGMDVLLVLLLATCLLTPAHGTPLEWDFAVTLRTKIQFMDSSWQTIATAAHEFDELSALTFDESEELIYFNDLKHRNGSIFSLKRDLIAANHVAEQTIARTGNESVGGLAYDPLNMNLFWSDTEQRKIFFAPIHGSATPQVLVDLSAEGGRPDGVAVDVCRRKLYWTNSNVTHPTVERINLDGSNRTVIISSNIDMPRGIVVDQLSDRLFWIDDLKGVFFSVESSKLDGSDRQVVLKDKHHEPLNLAVTNDAIYWTDRTTRAVWSHPKVPVIKVTTTSKPDEEDSTDSTDFKDPEPVAEDCPLVRVANLSEEARGIVARTGFYQRLQKDHHCASIVRKVKERVDEQSRKFEIRSLLDQKIKVLEDERCMNDGEYRAATDLCICPTGFKGSRCEIRECHNYCVHGTCQMSELAYPKCYCQPGFKGERCELSVCSGLCLNGGHCRVSKDENEAPSCECPAKFGGARCEQNSTEICSLFCRLLKHEPEMYVPFGCHSICEELAQDNSTNIAIPQYQHLEVCLTPRVWTSSVIIILVVGIVSSLLLVAVIVQGIRRLYKPKRPRIRKTFVVRKQARTNSAGDTPLTNRPLATEQCEITIENCCNMNICETPCFDPKLVEQTLSKSSCKEDKKILIHNMEDDLY
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
Sequence:
MSGLCACTLVGAAQVQQLEAALFAAGMPVEALMEKAGLRLAAAIAADYPAGGYPRVGVLVGPGHNGGDALVVARELWLVGRSVQVFCPRPPIKPLARAHLDYFQSLGGRVHTGAVPEEPGVDLWVDGLFGFGLERPVAEPYAGLMAQVNASGVPVAAVDLPSGLSSETGEALGGLAVRAARTYCLGLWKRGLWQDAALDWLGVPVRLEIGFSEAQVRSVLGEDHRSARLLLPDAARAGLPLARPATAHKYSVGTLLAVAGSRQYGGAATLVALGARSGGPGMLYLALPESLADRVAARLPEAIVHPCPQAENGALADLPGVDLEKFDAVVCGPGLGKAEQALVLRLAREAAGALVLDADGLNLIAGQLEVLAQRAAPTVLTPHPGEFKRLFPDIALADRQGAARTAALRSHAWIVLKGARTVVASPSGQVWVNPGGSPALARGGSGDVLAGLLGALLAQCENPEPAVLGAVWWHAAAGEWLAARHTVLGVDAETLALGLLPFLAADGP
The following text describes a protein:
Function:
Probably involved in guanidinium transport. In vitro, confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKWGLVVLAAVFEVVWVIGLKHADSALTWSGTAIGIIFSFYLLMKATHSLPVGTVYAVFTGLGTAGTVLSEIVLFHEPVGWPKLLLIGVLLIGVIGLKLVTQDETEEKGGEA
The following text describes a protein:
Function:
Probable tubulin polyglutamylase with a strong preference for beta-tubulin.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Associated with microtubules from cilia, basal bodies and cell body.
Domain:
The flexible c-MTBD (cationic microtubule binding domain) region mediates binding to microtubules. It is positively charged and becomes ordered when bound to microtubules: it interacts with a negatively charged patch on tubulin. The presence of positive charges in the c-MTBD region is essential for proper binding.
Sequence:
MSQKDIYNKYSNQSADDQQEEDDDENQESSCQLSPEKDLGESLQGEDLDEDQGVIGEDDEEQEESYDEEDEEEDDEENNQDQQNNSESNLQYDKTNQKNQQTEMTDNQNEFLAEDYLSQIKTNEKSELKYQLDIQSNLSGENVQDMDEKLKQYIELNGKNENQQAAESKKIENDEIMKKSEENVHEKVVDNNQKLNIQQNNINDYQEDIKKDQSNNLVDIQQNNEIIKEVNSEDQQQKNEMDNKQSDIVLAQEESKQSEQVEAPIVKQKKIELRPKVIYDPKNDVDQYTGDYSDSGESDEEANNEDDDEDEDDESENESRSRKNKAQLLKKKNNKKEQAKKQQVKKVYKKQTLVLNVADTKYPVVKFVGKKIFKWKLAYDMESMDFDIFWTDNAVQPEQLGRMQPYQKINHFPGMFSLARKNHLARNLMKMRKQFPDQYKFFPQTWLLPAEYNDFKNQFEKSRSQQKIFIVKPEASCQGRGIFLTRSLDDLNPSDHYVVQRYLNKPYLIDGLKFDFRLYVLLAGCDPLRIYLYYEGLTRFATEKYQEVNRDNIEDMCMHLTNYAINKDNPNFKFNKDKEKMDVGHKRSLTSVLQLLEDQGHDVNKLWKDIKRVLIKTIISAQPTLAHHYKSCQPDNFMNNMCFEILGFDIILDSHLKPWVLEVNHTPSFSTDTPLDSYIKKNTIRDSLKLMNCTCKAKNEIINQRKEIMQKRVLTGKKVKYTPEEKLEEIKKAQQKRDEYEDKHLGGFERIFPMEDDEDDNFTEYMQYALKCYEEQTGANIRRNTKKVTEDPKKITNQPKKLNQPKDLEKIYNTKIGAKLPPRKPNSQTTINKGIPGQNGQRPSSSQLNEEGETIQCEDQEQNKDEAIENAITRSASGRMHDFRIKKQNSPYNIHQKFKNKIQNRVAIGVKELKLAEEPFQFEENINGKPSNPNVKKIQAYITSEKEQLEIKNMNILQDQNYNSSRAVQAKKPQIEPQVLFVQEPQTKKLQILNQAKPPQQKLQFQLIDNTAAQMEEERRQWLIQAQRNLQYQLSQQQYQPQQKLTLLPKGPPIHPQTNVMQSIADIPNSSNSKEILAAVGGAISGQYKTDKRVTIKQKGQIQNQSINQLKDNNGLFLQPKLFEIQSFQSSQQQQAQQAIQSSLDQNLIGINQNMVGLNDLFVSGKSHKVQPHYQAQQDSYSYQKHNSYSNYYQK
The following text describes a protein:
Function:
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
Subcellular Localization:
Nucleus.
Sequence:
METQKIRVTTIAYYSRDSEMNVIPDSRPKTLNKNSTYFDRPYQTLPSLDGEFDDLGGGEFDLESFLQFIRQKDLYEGNCNKPDFVTNKNLLATIASFVPPTESSGSVQQKENIQILVVRVGGVYYLAKLSKENKKHRLFDCSFVFEHILTRATEDEMPMANGIVNKGVFKMEVPLGDGTFCTVLYTGELDAVDDRNNHVELKLFEGGLTEHVWKRRSQWMFWQSFFSNVLTLIIGSRNHPSLLEITDAKFDWPTNVLYDIETRSREEILEEVAKRFEGTEDHWTIEDGQKRLQSFFNLIKNSVKKDRDCYVITNDGSQWKIEQDHQKLAGTFRHVVEHILKSKGKMDINGNISYLPVREEWERSLIVKYLSENTESDETKAKKIVDRLGSGIGPEVAAVRCIGQPRHLQIVVNSIYQQRRCLRNVHKMKTSEFNGFYIERFISWEERKAFHEDQRNMARN
The following text describes a protein:
Function:
Component of the ATP-dependent clamp loader RFC complex for the POL30/PCNA homotrimer DNA clamp. During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC. The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit. Dissociation of RFC from the clamp leaves the clamp encircling DNA. Replication factor C (RFC or activator 1) complex acts during elongation of primed DNA templates by DNA polymerase delta and epsilon. RFC has an essential but redundant activity in sister chromatid cohesion establishment.
Miscellaneous:
MISCELLANEOUS: Present with 2360 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MVNISDFFGKNKKSVRSSTSRPTRQVGSSKPEVIDLDTESDQESTNKTPKKMPVSNVIDVSETPEGEKKLPLPAKRKASSPTVKPASSKKTKPSSKSSDSASNITAQDVLDKIPSLDLSNVHVKENAKFDFKSANSNADPDEIVSEIGSFPEGKPNCLLGLTIVFTGVLPTLERGASEALAKRYGARVTKSISSKTSVVVLGDEAGPKKLEKIKQLKIKAIDEEGFKQLIAGMPAEGGDGEAAEKARRKLEEQHNIATKEAELLVKKEEERSKKLAATRVSGGHLERDNVVREEDKLWTVKYAPTNLQQVCGNKGSVMKLKNWLANWENSKKNSFKHAGKDGSGVFRAAMLYGPPGIGKTTAAHLVAQELGYDILEQNASDVRSKTLLNAGVKNALDNMSVVGYFKHNEEAQNLNGKHFVIIMDEVDGMSGGDRGGVGQLAQFCRKTSTPLILICNERNLPKMRPFDRVCLDIQFRRPDANSIKSRLMTIAIREKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTINHENINEISKAWEKNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYFDDFDFTPLMIQENYLSTRPSVLKPGQSHLEAVAEAANCISLGDIVEKKIRSSEQLWSLLPLHAVLSSVYPASKVAGHMAGRINFTAWLGQNSKSAKYYRLLQEIHYHTRLGTSTDKIGLRLDYLPTFRKRLLDPFLKQGADAISSVIEVMDDYYLTKEDWDSIMEFFVGPDVTTAIIKKIPATVKSGFTRKYNSMTHPVAIYRTGSTIGGGGVGTSTSTPDFEDVVDADDNPVPADDEETQDSSTDLKKDKLIKQKAKPTKRKTATSKPGGSKKRKTKA
The following text describes a protein:
Function:
Member of the two-component regulatory system VanS/VanR. Functions as a sensor protein kinase which is autophosphorylated at a histidine residue in response to environmental stimuli, such as glycopeptide antibiotics. VanS transfers its phosphate group to transcriptional regulatory protein VanR, thereby modulating expression of target genes. Binds directly to, and autophosphorylation activity is enhanced by, the glycopeptides vancomycin and teicoplanin, in vitro. However it has also been reported that autophosphorylation, phosphate transfer to VanR and dephosphorylation of phospho-VanR are all unaffected by the presence of vancomycin, in vitro. In the absence of vancomycin, negatively regulates VanR-mediated activation of vanS, vanH, vanA and vanX, probably as a result of dephosphorylating phospho-VanR. May inhibit promoter-specific DNA binding by VanR. Involved in conferring vancomycin resistance.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGKLGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS
The following text describes a protein:
Function:
Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
Subcellular Localization:
Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MNPRKKVDLKLIIIGALGVGKTSLLNQYVHKTFYEDYQTTLGASILSKIIMVDNTTLKLQIWDTGGQERFRSMVSTFYKGSDGCILAFDVTDRDSFHALDTWRQDILQKTLQTEQVFPIVVLGNKIDLDAREVSQKKALDWCKEKDIPYFEVSAKNDINVEQAFELLARQALIRHRGIFENYLTDSIKLLPSGEPRNKCC
The following text describes a protein:
Function:
Controls stomatal patterning.
Subcellular Localization:
Secreted.
Sequence:
CGSNMNDHMQEGTWQQQSTSGEGAGLIGVESSEPPSCQGVCEGCEPCTLVLVRYHPPGAVGTDENFYPEVWRCKCRGRFYVPPEA
The following text describes a protein:
Function:
Plays a role in the organization of cell polarity via a planar cell polarity (PCP) cascade. Involved in the development of the hairs on the wings. Specify the correct orientation of the hair by limiting the site of prehair initiation to the distal vertex of the wing cells. Controls wing cell hair number by maintaining the integrity of the cytoskeletal components that direct hair development.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton.
Sequence:
MSIYLLCLTTNGGLPVFTRKKGECENLPFSTVASLNGFHMFFKSLGIQLEATTTSKQQPIQNQAPADAEEWTYIWRDRESITLIVCGCGVGSEQLLQTLADLVFGAIGMFITRAAEMAHATLLDRLKKDAKKYVPIVDAILEAACAGTQLLGYTDCLLAAENAQLLQCLNEFSGHCGSLFCCLVVGHRIAVATEGWWDLDTRDRELLLFLLNSSSTMQHDVPVYLPVKSPHIAYRFVSIPVASNSALCVLCGAENASFRELHAHAMSAYRNEGNLLAAAERCVPRSLPEHLEIDGNVLAIILINRHTRKSLFTRNLNQSASVKRIIVGDLQRLDILKKFFDQTMDAVHQFETQSSSNKTTLVDQYSCSDYHKCYAHMDELGNVIFLLFVAAVPSHAMRFLAQRIHANILQEKSVCW
The following text describes a protein:
Function:
Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.
Sequence:
MSCNPLRTAFTLQNPGLQRVVQRAPPIFANGYSSDSITWDSVRVLLVGAGGIGCEVLHSLALSGFADITVIDMDTVELSNLSRQFLFREADIGRSKAEVAAAAVECRCPGVRVRALFGRIEDQSDEFYRQFHAVILAVDSVAARRWVNQKVAEVAEWETFDMVDGGCYENIAARPIARRMRRIAYAMPLIDTGTEGYEGCCRVVLLRSVNPTPCIECDLSLYPSRRTVPLCTLENIPRLPEHCVLYVKFKLWEELRPHESPDADNPEHIAWMTVMAQRRKEAFGIEGPDIDDAFTLGVVKNVVPAVGFTNALVAAQAVLELVKLLTGVAFPVQCFSYYNGSTKCGLTSYVTDLIPNPTCSVCGPRPLLILSAEMTPLNVLLAIKTQVGMPPSVEDISHLDVTLRVRFAAGEVYLMYKSNNPLRTNVVATTIEEAFATSGYAAAFVEWCNSDAVVFTLECSGADIHIS
The following text describes a protein:
Function:
Essential for maintaining proper cardiac intercalated disk (ICD) structure and function (By similarity). May regulate cardiac conduction and the function of the gap junction protein GJA1. May contribute to the stability and proper localization of GJA1 to cardiac intercalated disk thereby regulating gap junction communication. Regulates mitochondrial respiration and mitochondrial DNA copy number maintenance (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein. Note=Localizes at the intercalated disk in ventricular tissue and cardiomyocytes.
Sequence:
MIRSVLLRALAARPPSAPVPGHLHRCLLGTHRRKIKPEQLELPNQTREFVYSLSPETRSRLLKELQTFESKTEDSGEASRLTAAQLRYILLHNAIPFIGFGFLDNAIMIAAGTQIELSIGLTLGISTMAAAALGNLVSDLAGLGLAGYVEALAVRLGMQIPDLSPRQVDMWQTRVSSHMGKAIGVAIGCILGMFPLLFLSDEEDKKPKKDSN
The following text describes a protein:
Function:
May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking.
Subcellular Localization:
Cell membrane; Single-pass type IV membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein.
Sequence:
MNDASSAKPDLGDSRAHSTVPIPQIRPRGVPVHQAEVSPEFRLLGPGRRRLYGPGSLWPIAFDLTQFRSPLAEGAPPALSRRPAPPRPCASSGTAGTAAAQPAEKPGAGEASAAAAMAGKELERCQRQANEVTEIMLNNFDKVLERDGKLAELEQRSEQLLDMSSTFSKTTKTLAQKKRWENIRSRVCLGLVVVGGLLIILIVLLAVFLPQSSDSSSAPRTQDAGTASGPGD
The following text describes a protein:
Function:
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.
Subcellular Localization:
Nucleus.
Sequence:
MAGLDALKSYGSDSSSEGDDDPDDALQRKEQGHDKIKTKLQKSLPAKQTSALPLPGEILSMFSSPSSEMNNPTEHHGRIRSFAHTPGNWATFVYIPADTPSLASLTETLMTCLPQDLTFHPSDDLHLSLSRTVCLQFHWIDPFTQSFRERVSGMRSFQCHIEQVDVYANDEGTRTFLGLKIGAGHDTLCDLVQLTDESLEEFSLPVFYKDPSFHVSFGWCVGDVSSRIGPRVLQDLQEKLNNHLGELSIEVQEILCKSGCKKFVFPLR
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
METTLSLSSSSSILPRTRLPISSSYSNLSFSASNSNTTSLLLKKARTRTRSTKRFTCNAFFGLGVPELVVIAGVAALVFGPKKLPEVGRSIGKTVKSFQQAAKEFETELKKEPNSTEEISVTNDQEDQDNKVSSTKDSV
The following text describes a protein:
Function:
Involved in cytochrome c oxidase complex assembly and is required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.
Subcellular Localization:
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Sequence:
MAGNGALRRSAREKCWEARDAYFGCLDRHSILDGLKDDTKAAQACSAEKTAFETDCVKSWVNYFLKFRVQQHQQQEAIKKLEAQGAKKLN
The following text describes a protein:
Function:
Beta subunit of AMP-activated protein kinase (AMPK), which is required for transcriptional, metabolic, and developmental adaptations in response to glucose limitation. Has a structural role, mediating heterotrimer formation, and a regulatory role, defining carbon source-regulated subcellular location and substrate specificity of the AMPK kinase complex.
Subcellular Localization:
Cytoplasm.
Sequence:
MGNVQSQEGETRAHAVPSQDATTTPDNANNVPKEPRAQSMISIAADDLNQEGEMSDDNQQEGGNNRTSQNGTSGSSGHTKRRSQTSGKKTHQPYSGPCVPTIIRWRGGGEVVYVTGSFSRWKKKIQLLKSEDYTVLLQLRPGTQRFKFLVDGIWCCSSDFPTATDAEGNLYNYLEVEANEKLGASIDERLSQVHTDLPMEEKSESEQYSTEIPAFLTSNTLQELKLPKPPSLPPHLEKCILNSNTAYKEDQSVLPNPNHVLLNHLAAANTQLGVLALSATTRYHRKYVTTAMFKNFDV
The following text describes a protein:
Function:
Catalyzes the conversion of a range of fructosamine 6-phosphates to glucose 6-phosphate and a free amino acid.
Sequence:
MSQATAKVNREVQAFLQDLKGKTIDHVFFVACGGSSAIMYPSKYVFDRESKSINSDLYSANEFIQRNPVQLGEKSLVILCSHSGNTPETVKAAAFARGKGALTIAMTFKPESPLAQEAQYVAQYDWGDEALAINTNYGVLYQIVFGTLQVLENNTKFEQAIEGLDQLQAVYEKALKQEADNAKQFAKAHEKESIIYTMASGANYGVAYSYSICILMEMQWIHSHAIHAGEYFHGPFEIIDESVPFIILLGLDETRPLEERALTFSKKYGKKLTVLDAASYDFTAIDDSVKGYLAPLVLNRVLRSYADELAEERNHPLSHRRYMWKVEY
The following text describes a protein:
Function:
May be a S-adenosylmethionine-dependent methyltransferase involved in fatty acid metabolism.
Sequence:
MTTGRLSMAEILEIFTATGQHPLKFTAYDGSTAGQDDATLGLDLRTPRGATYLATAPGELGLARAYVSGDLQAHGVHPGDPYELLKTLTERVDFKRPSARVLANVVRSIGVEHILPIAPPPQEARPRWRRMANGLLHSKTRDAEAIHHHYDVSNNFYEWVLGPSMTYTCAVFPNAEASLEQAQENKYRLIFEKLRLEPGDRLLDVGCGWGGMVRYAARRGVRVIGATLSAEQAKWGQKAVEDEGLSDLAQVRHSDYRDVAETGFDAVSSIGLTEHIGVKNYPFYFGFLKSKLRTGGLLLNHCITRHDNRSTSFAGGFTDRYVFPDGELTGSGRITTEIQQVGLEVLHEENFRHHYAMTLRDWCGNLVEHWDDAVAEVGLPTAKVWGLYMAASRVAFERNNLQLHHVLATKVDPRGDDSLPLRPWWQP
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MRAIEHSVEEEPLIKKAKLIDKVENCHEVSMLPLNETVVKGNEEVCLLDMEDKKETCVDVESNERKKEEVSVSSLVDRKHVVSGDENVEKKEEGSVISAVTSSDEVPVVKNNDSCVVSGDETVEKNEEGCVILAVTSSDEVPVVKNNDSCVVSGEETIEKNKEGSVISAVTSNDEVPVVKNNDSCVVSGDETVEKNEEGCVILAVTSSDEVPVVKNNDSCVVSGEETIEKNKEGSVISAVTSNDEVPVVKNNDSCVVSGDETIEKNEEGSVISAVMSSDEVSVVENNDSCVVFGGISGVNSLVLRKKLLVLDLNGLLADIVTPLKDVPADINIGRRAIFKRPFCDEFLRFCFDKFEVGIWSSRKQNNVVRITEFLLGDLKSKLLFCWVRWFLPCTLPFLKLVNIDFSGIYFLQDMSYCATTSVGSLENRYKYVVFKDLNRLWEKHDPRLPWKMGDYNETNTVLLDDSPYKALLNPPYTAIFPHSYNHQNKTDTSLGNGGDLRLHLEKLVEAENVQDFIKKNPFGQEAITEVSESWEFYREIIRMLRISSQTYRLRNIIR
The following text describes a protein:
Function:
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, rpn-6.2 is required for proteasome assembly (By similarity).
Sequence:
MSATPVTLKAVQSEVSAQTAKSSEAEVKRCEDLILSYSRQLAKEKDITGIRTLVESIRSFYDLVGKARASKLIRDIVEHALTIDQGVGPALDHGKKEKIDLLTNCIGWATSNKREFLRRSLQARLIRLYNDIRDFTNAQKLAQDLSKELKKLEDRELLIEVSVEESKSSFNLNNLAKAKTALLTAKTNTNSAFASPQLQASVDMQSGVLYSAEERDYKTSFSYFYEAFEGFASIGDKINATSALKYMILCKIMLNETEQLAGLLAAKEIVAYQKSPRIIAIRSMADAFRKRSLKDFVKALAEHKIELVEDKVVAVHSQNLERNMLEKEISRVIEPYSEIELSYIARVIGMTVPPVERAIARMILDKKLMGSIDQHGDTVVVYPKADAANQFTRSLKTIRELTKTVDVSYSRTKHFK
The following text describes a protein:
Function:
Anion/proton exchange transporter involved in iron and copper cation homeostasis.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MSSQKRADSSSSFDQAERRSLDENERKKKYFFNREGSGIDNFETDDRVNEIINEQNEENVIDQSRWSKLWRIWNVGYSWFILSIIGTTVGFAAYMLDIVTSWLSDIRRGYCTSHWYYNEKFCCWYSETMGSSCTAWKPWTYKFSLNYLIYTAFALLFVLCAAIMVRDVAPLAAGSGISEIKCIISGFLRDSFLSFRVMLVKCVGLPLAIASGLSVGKEGPSVHLATTIGHNISKIFKYAREGSIRYRDICVASAASGVAVAFGSPIGGVLFGIEEMSGGYDPKMIVYSFFCCLSAVGVLHMLNPFRTGQVVLFEVRYSGSWHFFELLFFCFLGIFGGLYGEFVMRLFFLIQKLRKKYLSRWGVLDAAFVTVITSLVSFLNPWLRLDMTLGMELLFQECKSSSSPELINLCDPSLRTKNTILLLIATFARTIFVTFSYGAKVPAGIFVPSMAVGASFGYMIGLIAEMIYQRFPNSVLFLACHGSESCITPGTYALLGAAASLSGIMHLTVTIVVIMFELTGALNFILPTVLVVALANSIGNMLGKTGIADRSIEINGLPLLEPEKSINSSNTINIPITEVMASNLITIPSIGFTWRKLLGMMEGYDFSGYPVVLDSRSNYLIGYLKKSSLKSSFEAAKLEPSFTFDQQLCFGKVDSVGDSKSSKFGESDRIDLSAYMDVNPISVLHTQSIANVAVLFEVLSPSVIFIEKDGNLVGLISKKDLLLASKYYQEDNDLVNPANRHRAVSTERINDSYENIELKPLKLNIE
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Miscellaneous:
MISCELLANEOUS: Present with 5300 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Sequence:
MLLQPVWKGCRWTQFVRPIRRWNSTGTNRGVPFSFKDISNQEDITNISYPSSSDSVLTKSNGSSEVYKPKEEVVKYILHGKFTKNNTHLTFSSVVEDKNFHKNKGLTYNDTMLYYLNLPQKVKISLSTGCLGFRKAARGEYEAAFQTSGRMFELIKEKNMLNKDIEVVMDDFGKGRAAFISALVGKEGASVVKKVVKISDATKLKFGGVRSPKMRRL
The following text describes a protein:
Function:
Catalyzes the isomerization of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR in the biosynthesis pathway for histidine and the isomerization of the aminoaldose PRA to the aminoketose CdRP in the biosynthsis pathway for tryptophan.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKLELLPAVDVRDGQAVRLVHGESGTETSYGSPLEAALAWQRSGAEWLHLVDLDAAFGTGDNRALIAEVAQAMDIKVELSGGIRDDDTLAAALATGCTRVNLGTAALETPEWVAKVIAEHGDKIAVGLDVRGTTLRGRGWTRDGGDLYETLDRLNKEGCARYVVTDIAKDGTLQGPNLELLKNVCAATDRPVVASGGVSSLDDLRAIAGLVPAGVEGAIVGKALYAKAFTLEEALEATS
The following text describes a protein:
Function:
Involved in C-to-U editing of chloroplastic RNA. Required for the photosynthetic subunit psbF transcript editing in chloroplast.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAISLGRVVVPSCTISGDRLFIPNFSAICSVSCGRINVGTGVISARRRRDIGGVLISSCLSTDSSSSPPSSSSGPKTKLYVSGLSFRTTEDTLRDTFEQFGNLIHMNMVMDKVANRPKGFAFLRYETEEEAMKAIQGMHGKFLDGRVIFVEEAKTRSDMSRAKPRRDFPKPQSKPRTFRTW