lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.
Sequence:
MPPRPTLLVPPSVTRFLKPRTSIVRSLSSLTTTITTSNTTSSHHTHQRRISSPPTPVTTTTATRSYSSWLLSAVSSAASALNNGSPGGGGGGNNNAPETVLRARRILPYPSAHLYNLIADVSSYSQFLPHCSRSVVTAWAEQPTITAATSPAEKGEAGTETETETQENGNGKTTKWPARGDLTVGWGPFTESYSSRVYCVPDDGEGLGIVEAVSGNATTTIPATVLQQFGYHQSSPSDDTTEKMEGLFESLVTRWTVRSVPPAPTPKKKKSQGGGEGVTDNDKWTEVALSVRFKFASPALGFAVGQLAGQKVDEMVAAFEERARRTWKR
The following text describes a protein:
Function:
Essential for the control of the cell cycle at the G2/M (mitosis) transition. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
Sequence:
MEISVDNKKPTNLQVKGQKMTTRKFGVDVSNNRRALGVINQKGGAQLYPCAVNKRTLPQANGNNENSVPNQVHRPITRKLAAQIANKKQCFPEDVLNPKQSSESFKVWEDMEDQPVPMSLETTEPQKDHMEVEMEDIFEEPVVDIDVSDTKNHLAVVEYVEDLYAHYRKMESYGMVSPNYMLTQQSDINERMRAILIDWLVEVHHKFDLQQETLFLTVNLIDRFLAKQSVVRKKLQLVGLVAMLLACKYEEVSVPVVDDLVFISDKAYSRTEILEMEKLMLNTLEFNMSVPTPYVFLKRYLKAAQSEIKLEQMSFYLMELCLVEYEMIKFTPSFLAAASVYTAQCSLYGLKQWSKTCEWHTNYTEDQLLECSRMMVKCHEKAGTGRLTGVYRKYNTSKFGYAAKCEPANFIVVEEGSQQ
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER (By similarity). The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER (By similarity). Binds the signal recognition particle RNA (7SL RNA), srpa-72 binds to this complex subsequently (By similarity). The SRP complex possibly participates in the elongation arrest function (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus. Endoplasmic reticulum.
Domain:
The N-terminus is required for RNA-binding.
Sequence:
MTNDVEMKSETEELPPFPTVHILQVVKDAQQQHGLRHGDYARYRKYCAAKLERMRKALKFTNSHNCQKKRKAKFVKKWLSVESVQNVQFLNFGIFESERRYAEAMIDKITLEDNPEKSRKKFSMINSLRKAVLHATNLEKIVQESERFDAPTKLEAQAYAAWMRGMCSFESRNWQKASESLKLAKTVYEKLAEATNNTTLSSIFKGRCREIQPQLRLCEFNIAESPGAVGTMTELMELRMQMGEGGDSSVDKLISEMRASATSAEVVTIEWGGAKSTVDDEKAKQVVQEWKQTEVELAQCQTPKEKMALFEKATADTRDAIDRISDIIRRKSSENADTTVLQSIKAYLEFLKMNGTASRYLAIIDNTKSEKKSKPQDLLRLYDSVIEIYKEVAEIPGADHDKNLIQAFEVKVEYYRAFRCFYMASSYSALHKYSEAAALFDRTVSRVQDAEGKLKKLKSSSFITNETQSSLNELRSEVESAKVTVRAARLASAAGDVKTDSELAKIIDKRPLLETVNEWRQWDVRNSLKDKKTIPVASLPPAFIPMPNKPIFFDLANFHLTMPNVDDRLEKLQKDRDATPKKAAKGSSAAAASSKTSNQEEEEQQGLTGMLSGWKKSFWGNK
The following text describes a protein:
Function:
Together with RGLG1, mediates the ubiquitination and subsequent proteasomal degradation of the target protein PP2CA. Functions as a positive regulator of abscisic acid (ABA) signaling through ABA-dependent degradation of PP2CA, a major inhibitor of ABA signaling.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MGGSSSKESPRGGGSGRRYERSVSGSSSYSSAWDQSSYYQTPNHPSASPVSSYNSGRQTPKNLERKYSRIADNYRSIDEVTAALSHAGLESSNLIVGIDVTKSNEWTGARSFGRKSLHFIGTTPNPYQQAISIIGKTLSVFDEDNLIPCYGFGDATTHDQDVFSFNPNDTYCNGFEEVLMCYREIVPQLRLSGPTSFAPIIERAMTIVEESGGQYHVLLIIADGQVTRSVDTDNGGFSPQEQQTIDAIVRASEYPLSIVLVGVGDGPWDTMRQFDDNIPARAFDNFQFVNFTDIMSKNIDPARKEAEFALSALMEIPSQYKATLELGLLGQRTGHCPDRIALPPPTYATQSMRNSPRTSRSTSFQNKPYDNGVSSTPPSTTHNESQQQFCPVCLVSAKNMAFNCGHQTCAGCGEDLHVCPICRSSISVRIKLY
The following text describes a protein:
Function:
Inhibitor of protein-phosphatase 1.
Sequence:
MAASTASHRPIKGILKNKSSTTSSVVSSAEQPGKSVDEELSKKSQKWDEMNILATYHPADKDYGLMKIDEPSTPYHSMVADDEDALSDSETTEALTPDILARKLTAAAAESLEPKYRVREQESSGDEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLNDEEEDEEMSETAAGESMNMEESSQGS
The following text describes a protein:
Function:
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Subcellular Localization:
Cell membrane, sarcolemma; Single-pass membrane protein. Cytoplasm, cytoskeleton.
Sequence:
MLKSGFAVLSGLLLVFLVPDALGNTYPARVGLNFMYRLDRETYTAILKPDNTGAVDPIVYTPTLKGHPGLPDWLHFIQRNSTTDGYMYGTPTKEDLGPVNIEIVAFNKNTFETNITTLTINVEDNDPLPFQVQFMVENKNVEEFFHGDTRTRFLRDVRRVWQQNRGDLYITKVVSALDMGHRNPLPLPELYEGNWPSCSGRYFYRRSMELIRNAPAHCSFPGWVYIHVGSERGYSAQLQQAAGQVAVCELNPGIRPVVSIDSSIRNFDMNWCMFKLFEPEETATPAPLAPGAGVMGGVYVPRELTDTGRDFTLYFILIIIIPCIILIVLLLLLTYIMCGRRQGVQKRDQATPAIQLTHHASIREASKELRDLSQKRDIKPRSTLPMFNAASPHRGDEGTPLTRAPQEPADETPRAPPPYRLPPDFPNQEESSFINSPPRDNSRGNVSQPGGSSNASPSLQRRPPPFMRSGEQIQGRNQPGDRGRPVVREFTA
The following text describes a protein:
Function:
Regulates the activity of glycogen synthase. It is most probably a regulatory subunit for protein phosphatase type 1.
Sequence:
MVIQTATTLSPAKARPSFPHNDLIKSMSDSLISRPTHPPIRKLKSSLKISHPEPISRSKSEIFCTSPEKNVRFAIELTTVKRFDKNAEPSSISNENSPTLSPVDSNTAADDVQLFNNEDCWFNDSSLVTNLLKNEKKFRYMNSLNNMFKLDLYDSEDEDDIDEHINSQAEYGYTYNSLSTRGKTSENKSATSSLATQATNICDWKLHCTDLVPFKIAPPLFTKTLSASDLQGQLTKYLNGQNVKLHSLTQLGDDSSKITGLVYVKNLSFEKYLEIKFTFNSWRDIHYVTANFNRTINSNVDEFKFTIDLNSLKYILLIKRIITMEKNTSSCPLNIELCCRYDVNNETYYDNNNGKNYHLFMTTFKKGGETKEKIPVVVEPASQTDAAMSPKEMKARFVSSNPTLSRFLPQSRKFSEDTDYYNTSPLKHLYHNDTTSWVKPKRLNVVLDKLENATPPPPSSALANDTARTGKITKDKNNVLAPPTASNSIDLPILGSQHQSLYSGSSSYSSSSSSISSSLSFASSNNSSTNSSSASCSFPLTELDNFDYANLYEPNDTFTTANLFNHSLNSLMPEISTPSFFGGFRNENTINNNDSKNLVTSLEDSYEDKQSVITDTTMDENNKTSTINNSTDTLIKPSKENGTVKENKSSANSTSAPSSSQNRASTILNDHSNGKSDLKYVNYQSLLDSHCFYNHPSSPNLQSTSFSSAAPFSGISQASDIFDYENEDSDSNQIAGEIDNNSFPPHFYLDEDDKSACLSDDALIDHHRNTNPFINTFSSSPPILSQEVDRWRL
The following text describes a protein:
Function:
Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox8 and sox9 to induce neural crest progenitors. Acts downstream of wnt-signaling at the neural plate border. Involved in the specification of neural crest progenitors fated to form the pigment cell lineage (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The transactivation domains TAM and TAC (for transactivation domain in the middle and at the C-terminus, respectively) are required to contact transcriptional coactivators and basal transcriptional machinery components and thereby induce gene transactivation.
Sequence:
MSDDQSLSEVEMSPVGSEDPSLTPDPLPPHAHSSPDDDEETKVKKEQDSEDERFPVCIREAVSQVLSGYDWTLVPMPVRVNGGSKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNENDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKPNPGEGDGSSEAEGGAASIQAHYKNSHLDHRHGSPMSDGNSEHSAGQSHGPPTPPTTPKTELQAGKSDGKRDGSRSLGEGGKPHIDFGNVDIGEISHDVMANMETFDVNEFDQYLPPNGHAGHPSHIGGYTSSYGLSGALAAGPSAWALAKQHPQTDSKAQVKTESSSTSHYTEQPSTSQLTYTSLGLPHYGSAFPSISRPQFDYADHQPSSSYYSHSSQASSLYSAFSYMGPPQRPLYTAISDSPSVAQSHSPTHWEQPVYTTLSRP
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MDLLGLKELDNNKLVSKAKENGVEFSDLFLLSSGYLRDRENASASVSSKNERMVLNEERQNCWTKRNDPKGLTYYQLLKPSEVEILSRPETRRKRMACQVFFLNYYISTIEYHKLRKERLEEFTACTSSLKQSKQKRLWKEHCGRERAFLRKKRTKIQCSHFDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNERDILTNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAISAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSNQVNRLQHALVSAVNPQRPYLTQKQRRNIYKALLEKNENKVNSVVGSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVGYPPFSGSTLQETWTNLYYWREMLQRPSKNENGIYDKKARSVSDEAWSFITKCLTEPTSRFQSTIEIQKHPFFKRLHWNGLRKRAVPPFVPRLENQLDTSYFDDFNDEQVLDAYKDVYEKQRKAEQKAKSNGVMNGNQRQFLGFTFKYRPNARKPLVGRHREKRQLRKEKPEKKNNSTKQKDLITVSHNKGTTAIEDLDEDKRSKTKGHKTKSSRVHRLLERKGKDLYEFLL
The following text describes a protein:
Function:
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Sequence:
MGRGRYPARLYVTAPPPEIAARYYRSWPAKELYHTPEHFPPVSAEGLFGYNAPLTLEFGCATGEYLCALAAAQPSSCFVGIDIVAKPLYRAVERAVAGNLSNILFIHADARLIYQRIPTAALHSIILHFPPPLLRNRQRNQLLVSPQLLECAARTLVPGGYLSFLTDHPALFALMQELLPAFPALRATPASVEELAVFESHYHRRWAARGRTISGLRIERVMED
The following text describes a protein:
Function:
Could be a 3Fe-4S cluster-containing protein. Probably participates in a redox process with YgcN, YgcQ and YgcR.
Sequence:
MSVARNLWRVADAPHIVPADSVERQTAERLINACPAGLFSLTPEGNLRIDYRSCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
The following text describes a protein:
Function:
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNQASAIAILVIFSLASGYLLGSIIFADIFSKILKKNVREFGSKNPGATNSMRVFGLKIGFLVAIFDAFKGFFAFLLTWILFRFGLQGYLTEKVYQSTYFLSYLSCFAATIGHIFPLYFKFKGGKAIATTGGSLLAISLWWFLICLLIWIMITLITKYVSLASLITFFVLAVIILIPWLDYLYFFNSDPLKSITYQNEWYIILFFCLWYWPLTVVVFWLHRANIIRILHGKESKITQLN
The following text describes a protein:
Function:
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAQSVLVPPGPDSFHFFTKESLAAIEQRIAEEKAKKPKQERKDLDDDENKPKPNSDLEAGKSLPFIYGDIPPGMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSAVYLLTPFNPVRKIAIKILCTLFSMLIMCTILTNCVFMTMSNPPEWTKNVEYTFTGIYTFESLIKILARGFCLEGFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRHKCLIWPPDNSTFEINITSYFDSTAGENGTYVNTTVTTFNWAEYVSDDSKYWNNFYFLEGQNDALLCGNGSDAGQCPEGYMCVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATMEEAEQKEAEFQQMLEQLKKQQEEAQAAALAAAADESREFSDVGGVGGFSESSSATSKLSSKSAKERRNRRKKRKQREQSEGDEKDEDEFHKSESEDSIRRKGFRFSIEGNRLTYEKRFSSPHQSLLSIRGSLFSPRRSSKASLFSFRGRAKDIGSENDFADDEHSTFEDNESRRDSLFVPHRHGERRNSNISQASRSSRMVPVLPANGKMHSTVDCNGVVSLVGGPPVLMSPTGQLLPEGTTTETELRKRRSSSYHMSMDFLSDPTARQRAMSIASILTNTMEELEESRQKCPPCWYKFANMCLIWDCCDPWLKVKHVVNLIVMDPFVDLAITICIVLNTLFMAMEHYPMTPQFNNVLSVGNLVFTGIFTAEMFLKLIAMDPYYYFQEGWNIFDGIIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISNDCELPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRIQRGIDYVKRKVREFVQKAFVRKQKALDEIKPLEDLNNKKDSCISNHTIVDIGKDFNYLKDGNGTTSGIGSSVEKYIIDESDYMSFINNPSVTVTVPIAVGESDFENLNTEEFSSESDLEESKEKLNATSSSEGSTVDVGVPQVGEQPEAEPEESLEPEACFTEGCMRKFECCRVSVEDGKGKKWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQMYFTNAWCWLDFLIVDVSLISLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINTTTGEMFSIDEVDNQTQCEELIERNETARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVEKQPHYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKISQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQAFDISIMILICLNMVTMMVETDDQTDAMETNLYRINLIFIVLFTGECVLKLISLRYYYFTIGWNIFDFVVVILSIVGMFLAEIIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMLCLFQITTSAGWDGLLAPILNSGPPDCDPEIDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAASLDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESEEMDLLRVQMEDRFMQANPSKASYEPITTTLKRKQEEVSAVIIQRAFRSYLLRQKVKKVSSLFNKDRIKAGGDTHIKEDMIIDKLNENSTPEKNDMTPSTTSPPSYDSVTKPDKEKYEKDKSEKEDKGKDSRDSKK
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MSNVIRSPEHSSRATGLTFIGFLLFASITVAPAQVRALEYSGPNGPQSWGGLCNIGRSQTPIDIVSSEAVVDRSLSVLKVDYSSRTRATITNSAVNLELEVDGEMPFGKLYLDDTYNLIGFHFHAPSEHEINGQSYDLELHLVHQIDSSNSTDLAVIGLLYNQGHDDSSTDLFLQQVFDALPSVLVPNTTRYMDTNLDFCPLYPMLAGSYARYAGSLTTPPCSENVIWTVMLNENLRVSPRQFEAYKSVFEAPNSRPLQNLSGRTVTFF
The following text describes a protein:
Function:
Regulator of the mitochondrial protein import machinery that is localized in the mitochondrial intermembrane space (IMS) and facilitates the transport of proteins from the cytosol into the mitochondrial matrix. Not essential for mitochondrial protein import but induced and required when mitochondrial import is compromised. Stimulates or stabilizes the translocation into the mitochondria of proteins such as OXA1, ATP1 and COX12.
Miscellaneous:
MISCELLANEOUS: Present with 768 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion intermembrane space. Note=Imported into the mitochondria via the mitochondrial MIA40-ERV1 machinery.
Domain:
The Cx14C/Cx13C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system and the subsequent transfer of disulfide bonds by dithiol/disulfide exchange reactions to the newly imported protein.
Sequence:
MVDNRRTFTAPQSLLETNLTFPNDEPSLTTITVTRERCVDPSLIDSFLRFLRHGSDDIIRQKLNNYRKGSINGKNKCKEFLKQELYPNWQIRNNIISFCEKEAAEMKNETDQQCGNNKKTTAEPLIDARIDPYAARERAEKQEAQYKDWTKVTEWVANNRKIEQILTSTTEGILRQNCEQNNDYLKEFTQFCKDNS
The following text describes a protein:
Function:
Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation.
Subcellular Localization:
Cell membrane. Secreted, extracellular space, apoplast. Note=The precursor of SCOOP19, PROSCOOP19, accumulates at the plasma membrane and is proteolytically cleaved to release the SCOOP19 in the apoplasm.
Sequence:
MCNIVVFLLTLTLFLFSGLSNTAFARVQYEPLKPKFGARVWDQKMIKNIKIEVDGSCSRRAPGRRRPPNRPPKPCTKP
The following text describes a protein:
Function:
Represses the expression of both the krueppel and knirps segmentation gap genes. Binds, in vitro, to the krueppel regulatory elements CD1 and CD2. It is required in the early embryo for the development of portions of the head and abdomen.
Subcellular Localization:
Nucleus.
Sequence:
MLMHEKLMAGQFFDLKTDRKPLMHHHQYQHHQQQPLHHLPHSQLPVQGSLGLPKMDLYTAYAYQQQLLGAALSQQQQQQQQQQQHQQLQQQHTSSAEVLDLSRRCDSVETPRKTPSPYQTSYSYGSGSPSASPTSNLLYAAQMQQQQHQQQQQQQQQQQQLASLYPAFYYSNIKQEQATPTAAPPKVTPTANLLQTFAAASAAAAAAAAASSTNSPRPASNASTMQIDVLENPLSPAVEATTPTTSSSGEAGKNTRPFKAFPRDPLVIAANFAATDVLLDNPRVERYTEYRKRVLEQIRSSNGGSRTVTNPKMRRTNSRSGSVNEGSSSNNNSESEDRAAAEESSDCDSQAGNFESKSATSSSSNLANATAANSGISSGSQVKDAAYYERRRKNNAAAKKSRDRRRIKEDEIAIRAAYLERQNIELLCQIDALKVQLAAFTSAKVTTA
The following text describes a protein:
Function:
Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
Miscellaneous:
MISCELLANEOUS: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
Subcellular Localization:
Nucleus.
Sequence:
MEARMEWTDRIDQSGNDTDEAVHDIESDAPVEIFNEDVERDETDDDQLPCTSDHSEDELKEYDVEEEKAAVDVKEEEELEEGAEKIIIEAKNFREWELFFMLRSPFGAVLKFLVVNGEISESMRTEMNFHLKELFDCGLPIKKEYEKTEMWNGLTFDDVEEVARIMKALSLCVVAIVERLDGNIRDHVTSEWFKNEKCDSEMAKTFSNMALDRNMANARALNKGYKPFSNEVYGETSFDQIENILNELPLSESDVMVDMGSGVGNVIIYAAAYSKARRCIGIEVSEGPARRAKKIKKDFIEIMNFYGKRYRPFNLIHKSFLDDKFKKLITQVVVTSDMFLDVSKDITLAEFPCSWADGKNLRFQPFSINKEKLIRLIAKRVKEDEKRLAMKRAKKGGNIVKKEMKKAKKEEKDNEETKENGVSKKTVKAKGTSKSSRAVLGNSLVRNNSAAPRSIATPKCTTKQNRKKSVISEKEQGDGSFKYETAWMNYSDRTWEPRESFEGSVAIKMADDLDRFLDEGASLPKWFSDFKKKMEEEKETSSSSSRKVAKRKAVLDEVDTIKEDTNIAEHPLPPQTAYHFWMYLEGWKYGVTASVEWKKISDKTKWKEMEKTDKARHESEMKLYMKRKM
The following text describes a protein:
Function:
Involved in the abaxial cell fate determination during embryogenesis and organogenesis. Regulates the initiation of embryonic shoot apical meristem (SAM) development. Contributes to the repression of KNOX genes (STM, KNAT1/BP and KNAT2) to avoid ectopic meristems. Binds DNA without sequence specificity.
Subcellular Localization:
Nucleus.
Sequence:
MSSMSMSSSSAPAFPPDHFSSTDQLCYVHCSFCDTVLAVSVPPSSLFKTVTVRCGHCSNLLSVTVSMRALLLPSVSNLGHSFLPPPPPPPPPNLLEEMRSGGQNINMNMMMSHHASAHHPNEHLVMATRNGRSVDHLQEMPRPPPANRPPEKRQRVPSAYNRFIKEEIQRIKAGNPDISHREAFSAAAKNWAHFPHIHFGLMADHPPTKKANVRQQEGEDGMMGREGFYGSAANVGVAHN
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MTKTLYYRKLGRTSAHRQALLRNLVTSLVKHESIQTTWAKAKEAQRFAEKLITMAKRANPQNNRKGLAEGMVFEKETTLKKVFDVLVPRYNGRRCGYTRLLKLPPRSTDNAPMGVLEFVDGPKDIRFHMTAKTVGICLAQQKALTPITRKNIHKVLLFRKNGKAEFDQLVQKEKESEHARLKEDHEDEKTVKKDWKRGDPIPRPTYI
The following text describes a protein:
Function:
RING-type ubiquitin E3 ligase that binds ubiquitin and is required for seed germination and post-germination growth.
Sequence:
MNSASVSGESSLSDMIQTVHFSSGNPRIGETRGVMHLISDNAVSSSSSSSSSNLPIGRNPLVCVLGVPNHMTYADFCQFCGSFIQHILDMRTVRNDDIENRYSILIRFDSQESTDTFFQHFRGKQFNSLDEDVCRLLFALDVQFTGYSGSIDHTQPSAAGPIEQPTCPVCLERLDQDTGGILTTMCNHSFHCSCISNWPDSSCPVCRYCQQQPENSVCCVCQTTENLWMCVICGVVGCGRYKEGHARRHWEETEHCYSLELETQRVWDYAGDNYVHRLIQSKTDGKLVELNSHGSLSKDGCGSCEYSDSGMTDALLNSKVDMIISEYNELLQAQLENQKQYFEKLLQNVKEETEQKISEAASKAISQRLQKLQTRFDRCVKEKQFLEDLNENLVKNKDVWSTKITEMKEREKKAVRAKDEKIQGLEEQLGNLMAQMDGESEVSETKEVQDATVSTTNTSSSGAGNVIHANKKKSNRRKG
The following text describes a protein:
Function:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Sequence:
MSSDSAKENASVVDSSVTEWRNDIGNSDDPESSGYKFKENINPTRADKGGHSHGQIGHPAGIGVEKCHNTKYFVIKSLNHQNIHLSIEKGIWATQIMNEPILQEAYHNSGSVILIFSVNMSGSFQGYAQMMTSIGRGRDNAWSEGTGKSNPWGRSFKVKWLCLNDLPFHKTLHLKNPLNDYKPVKISRDCQELSPDIGLALCKLLDGKNDTDGLLTSLSRDEFSLKGHYVSTPSSMGDEDCNFPPLHMLWPMPLPYSFLFLPKSTRSK
The following text describes a protein:
Function:
May act as a GTPase-activating protein for Rab family protein(s). Involved in neuronal projections development, probably through a negative modulation of ARF6 function. Involved in the regulation of synaptic vesicle trafficking.
Subcellular Localization:
Cytoplasmic vesicle membrane. Endomembrane system; Peripheral membrane protein. Mitochondrion. Synapse.
Sequence:
LTETSNKRSLKTHLRENLHPANHDIRSVLYKRLVRKVECNESMFGAQMYTDFENEHLIGVSGILPPPSFCETEDIPNFCLNGNGKATLMKVLNCINYQFPQVTYSPLLPVAVALFLHYDEDPAQVFSHVCRLIFSNSKSIHYLDANKKEVDASTHLLKELTQKYSNASHKSLLSLTSNPDNVYSQWIRCLFHGLPFTYTAILFDMYLLEGYKALYRLSLSVLKFYRKMGVANASDIVSAVFNFNQNIESKVSINMLFRKAFGFKLPPSKEINRRHRKMLMTSNNPNLQDTTRSPMNQWTHVTTIKQVESEIASQSLLTTLYKWLPDSTTVLSPVVLFSTNKHGYNLTSFFSCCDLHEPTVLLIKTVTDAVIGAYLSTAWEERINSKGYFGTGESFVFKLLPEPAVYKWSGITKSTNKIPQRDDLFMMADKNGIKIGGGGGISIAIDTSLLNGISQPSSTFNNPSLVGENGTFVCSMIEVIGFHNA
The following text describes a protein:
Function:
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
Sequence:
MRISDQSLTIPLKELLNLMLIVREGDLREGNLMRQGKGWIHIPGMGHESLIAITHHLHREDYLFTYYRDRALMLGKGFTAQQLAWDYFACAKSSTGGRGMPVHCSAKHLNIFPPATPTASQCLPAVGAAWGIKHSEKTDVVICTIGDASVRQGEFYEAVCMAVQERLPVIFVVEDNAYGISTSTKHQLPFRLGIFNEEIFVRVDGRHPAEIFNHSGQAITKARQGNGPTILWVELDRLVSHTNSDDHRIYRPKEEIDAMLQRDPLSVLARHLINAGELTATEWQALQFKTAMTIDEIYQQAERENSPNPDQILVHLYGSKVDHQCVPFQPVERTTTMVAAINQTLREALQLYPQMIMFGQDIEDPKGGVFGFTKGLSSQFSQRVTNSPLAEATIVGVAAGLAATGYKPVFELQFIDFITPAFNQLVQQIATLRWRSQGDWSCPMVLYAPYGAYLPGGSTWHSQSNEGWWTHIPAEVLNVRN
The following text describes a protein:
Function:
Acts as a catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSPGGLHSAHLSSSASRSEAVANAANAAAAAAAAASGSPHWQQQIVKAEISRQSNSPHHHARAAALAARSATSSAIAIQDPSKGIVTPQVAANGLFVAKKDSSAANGGGADDGKGSGADTAPATTNGAAPISSTSAKDKQTWSTIDMGGLALKNIANEVYRYSFLTSLFINHNALTTLSSDIVKLRHLTVLDASGNKLSSVPPELGMLTSLRELFLFDNNLATLPPELGTLHQLEMLGVEGNPLQDNLRSLLQREGTTAVIAYLRDSCPVPLPPPEREWIMIDPDLPDLDADKHANDATQESFNVLSYNILFDRYATAQMYGYTPSWALAWDYRKEFILQEVMSYSADICCLQEVGVEQYEDYFLHHLSQQDYEGVFYPKSRARTMRDDERRRVDGCAIFYKSNKYQLIEKQLVEFNQIALQRPDFKKSEDMYNRVMTKDNIAVIALLENKLSGSRIVVANVHTHWDPAFRDVKLVQVAMLMDEVEKAGARFAKLPPKPSVAEGYPPPPKYTHANQIPTIICGDFNSVPETGVYDFLANGAVPGDHEDFMDHVYGNYTAQGLQHSYKLESSYVPIGELPFTNYTPGYEGAIDYIFYTKNTLSVTGVLGEIDKQYLSKVVGFPNAHFPSDHICIMSEFNVKRSDRGSSSTTAREVHHPTSSSNASSMPRR
The following text describes a protein:
Function:
Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
Subcellular Localization:
Cytoplasm.
Domain:
ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site; The C-terminal coiled-coil domain is crucial for aminoacylation activity.
Sequence:
MEIKEYNPREIEEKWSRYWIEKALYHVEKPDKRKKFSVVIPPPNVTGSLHMGHALNATLQDVIVRWQRMRGRECVWVPGFDHAGIATQYVVEKQLAKEGKSRLELGREEFLKKVWEWVPKSRNAIRTQLTKLGVSVDWKRERFTLDEGFSRAVRKAFRTLFEEGLIYRAEYIVNWCPNDRTALSDLEVEYEEEKGSLWYIKYPIVDENGKDTGEFITVATTRPETMLGDTAVAVNPNDDRYKHLVGKRARLPLVNWERKDLRGNSVSNLIPIIADERVKMDFGTGAVKITPAHDPLDFEIGKTHDLPFVRVIDETGRMNENAGDFAGMDRYEAREAIVAKLREDELLEKEEEITHSVGHCYRCKTVIEPMVSVQWFVKVSDPRIKDISIKVVEEGIKEREEKELFVQLAQVEELSVVIPLKEEGRHKIVVVLDKTAKFLVGKREGELAYIYYPKGDERTLEFAKRLAEEFKDYEFMVAYEGLPKIVVMGNEQLVEPGSYLFVYDGKKLDLYKLEGEKPKFLKTLGKGEADLEVTQKSIQIKPERIKKVEEREKRVKFIPEHWKKFYLDWMYNLKDWCISRQIWWGHRIPVWYCKDCGNVNVFTDDDFDRAHDKIIFNLIADGKIDQEFTPEEVEKVLKSPHFVHPEMTVLDFYKKFVFHRYYNMDITADSLRLLFTQDMNPMAMLTPGVSTRNIYKYDSQKKKWKMVLRCKKCGSENLEQERDVLDTWFSSALWPFGVFGWPESTEDLKNLYPTDLLVTGFDIIFFWVARMIMMGTHFMKDIPFYDVYVHALVRDKYGRKMSKTIGNVIDPLDIIERYGADALRFTLAILTVQGRDIKLAEEKFEGYKHFANKIWNAARYVLMNTPEDFIARIPYMAPLKPEDKWIITKLNETAEEVNKALENYQYSQAAHAIYEFFWSDYCDWYIEFTKERIYKKAPEDNEEEKAKVENERTTALYTLHYVLEKALRILHPFMPYITEELWHKLPNAEGESISLAEFPQKNEDEIYEEDKQKVERLKEIISAIRAIRSDLQIKPSEKIKASFKTESEFSRRVIQEFKNHILNLAKLESFEEVSQRPQNTVATFSKDTEIYVHIEGHVDLDKLIQSYEKKREKLLKELERVNKKLSNENFLKKAPVEVVEKEKQIKEELENDLKKVEEILKVLRS
The following text describes a protein:
Function:
Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
Subcellular Localization:
Cell projection, filopodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein.
Sequence:
MSRTEEVNKMTENVYKGILDQFNPSLKNFVTMGKHYEKALTGVTVAAKGYFDALVKLGELASDSQGSKELGDTLFQMAEVHRQIQVQLEDVLKLFHSEMLTQLEQKLELDIKYLTATLKKYQSERRSQTESIERCQSQLKKLRRKSQGSRHPNKYGDREMQFVELMSRRQVELDSLVATGYKSALTEERRRYCFLVDRQCCVTKLLINYHSKVRELLSQKLSSWQQSCSQPTKLPERALNLLRHTAPQSPGAAGVAEVLRHTKIGSSHPEQRVSVQEVPPLLNGDSSRSQQQRLVPASGSQTDTGPQGSPQTSHSASSNGGAAGSSSQGASPQRASTPQSASASPLPDGVDNISSSIPATSSSSLQQGSLLPATNTSNLSPSLIPSTVMSLSQISPTSGSSQGMTVPIPHSAPHSPPLSHSAPLSRAMTPVQMLHPQVGPGGSNTLSLSHNPWMLKAAEMSATATLPLPRRPVSEMRLGGFQGSSLPRSLPLSGVTRVEAMFAHTPGALEGVGGNIGGGACLLHFVPGDNITLLISEPRDGWHYGQNERTGRKGWFPFSYTQPQHSRIDQLERSLFLSKANSTSTGQLDKLVSSSLTPESEEERALPPQRVSTFRPRPYSMADSNKITSDLASSPPSPTRPNPFAHVRLRKTITNDRSAPIIE