lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSEENNLIEILEEGHKVDIAKYIDYVTTPQAGAIATFSGTTRDTFEGKTVMELRYEAYVPMATRYLSSICASARSNWDIHKIAVAHRLGAVPVGETSVFVAVSSVHRGDGLDACKFLIDELKASVPIWKKEVYANGEVWKENAEFLEKRLELAETRGSLVKKHVAGEHKRSCCGSKVRVQEDEDHTDIAGDNKE
The following text describes a protein:
Function:
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MILIQERYPSFVFPEIEISRTDTFIFYNASGHCLPSIKFVWRCVYSARSVCTCPHSPYPMLKRLQSKLPQSDTLHGHLCNLHLHSFIEPFIFHEVISLYEQDDSFKHFLTATIVSRGRLAVVNQLIMPDYVNDLTYPAFIRLLSSVSSRESVLHTHVQGVFDPSDKRPIDDRNSIHTAIDALCETGWRKLESVLGRYEFAKLILGNMVFMELRKDCYFQVSGPRIDDILLCRPTHKVQTELLLLKAPPGKVGKRVPRKGILRCKQGMYYSLGKTGYNLSVRDLVDSKDHKVEIEHVLESIFPYTYDKTQSKRIPKRLVPFVQIASTIVKKCQQYNFLRLLDAWFPLNRDYEDGHSVNDVVSFCFAASHLLFPHVLFGSADNWAVLRSKYVYYLNLPSRTSPHLDTMTGGFRLTEINWLFTSDMNLKKSRDDMLKARELFEQLMIWVTNRFLPQILRSFFYFTDSLTSDQIIYRHPVWQRKTRSTLQELKRTQFSSKVLTPSDLGISKFRLMPKKSGFRPIVSLGRPVQSPRGKKPISVNKKLSKLYKILYQEFRLGGNNKCGLDSVHLLKKVLGKYEKAIKGQIQGLKFVKIDVTAAFDTIPASKVKDISKRLLDCESYSLHSHSRILPMSSKTVLRWFTTSRACNGRSEGALQAFRRLGNKGIIVDENKSDSVGKQLLYKLLNDHLFRNDVFIDGQVHRQVRGIPQGSILSSLFCSMVYEEMVREKFSDLVDRPDTCLMRFVDDFMLITTDTAIATEFLNRALKGLPDYGVSVNRSKCLVNFPLSVGGVRIAQLEEGEMMPFLGMKIDPCNLQIHRDYPYSSALLWVDKGVKLAAVRHRAKEYFSARFPRLLLNKSVPEAVVLKNVSAFFRYVFLRAIRTFEHFGHVSESRITQEAITLAAEMIDISMCVVTPKCPHVGLKKLRGWLTKISVLSIERRR
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MARATVELDFFGLEKEASSKSQFHSLLHRKRSFRGIHNAISKIDPQLLKSVIGSASISLPPTPEAAANHNVLSPLPLYTPLYRPTASESLQHTSQMTIFYNGTVAVFDVPRDKAENILKLVAEGKAEGNPTVAIPSTDHQQHLLASLDGDLPIARKKSLQRFLEKRKERLTTASPYAFPCPHLT
The following text describes a protein:
Function:
May play a role in immune regulation through regulation of the macrophage function (By similarity). May also play a role in trafficking of proteins via its interaction with unc119 family cargo adapters (By similarity). May play a role in ciliary membrane localization (By similarity).
Subcellular Localization:
Cytoplasm. Cell projection, cilium.
Sequence:
MEVDINGVNRTNNSVPSTAEGSSPSKPDPEKPRCSSTPCSPIRRTVSGYQILHMDANFLVGFTTGGELLKLAQKCATTEETPGESLPAFRSKQLESGLSRSSRIYKARGRQFQPYDIPAVNGRRRRRMPSSGDKCNKAVPYEPYKAAHGPLPLCLLKGKRAHSKSLDYLNLDKMNIKESADTEVLQYQLQHLTLRGDRVFARNNT
The following text describes a protein:
Function:
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MDENRSKSEVVVQNSSMRMKNEGQPSAQGALSVFSSATACTEAICFAKKQPYHGPKAGTQSSLMNIPNENAESQYASCHMLSDKLSQAKLHHDDRPSDVALIESYSKHHQVVSFIWAVCRSIVPVSLLGNSSCWKSLQRNISKFVKLHRFEKFYVKQCIHGVKMSCFHFLSKVRSSKCSCNGNSRSEFGGSIRKDSRKPCNSKMILVGNLFSRWMRWFFFDMIVPMISANFYVTERESRKHELFYYPKPVWRTLVQRTIASLEGDKFKLLDQVFVRNIISKRSFGFSKVKFLPKNKCLRFLTNLRASSIVRLSNPEFGSRYCSIGAKEKATMHRKYKSAQDRGFVRCRSVNSALREVYAILRRVKVEKPEILGSSVFDYNDVHQRLHQFISKIKNRTSKMPEIYIVVADVRKAFDSIDQDMLIGILKDILQNDEYVMRKHVKISCRKKSLRILHDHVYCDYSSSNCCDSVSEPSVSAGSILIDQGISLRIQKEKLLYVLREHLKCNILQVGQNFYLQKVGIPQGSVLSSLLCSYYYGHMERSLILPYLQRSSSDLVVSSSKYTINECTTELANNAISGVESLKYDMACLGCPNITDLGKNNLLPFTEHHATEVNTVTSDKECSTSGENLLLRLIDDFIFISTSKEQAGRFFNRMTRGFRAYNCYSNKTKFGTNFGMTQNHGLINRIYSGADGILFLPWSGLLINCQTLEIQADYTRYFGINIRSTLTIELHAKPCYRLKEKLLNFVKTRCHPIFYDSNINAPATVCLNAYQAFLLCAMKFHCYIHSMQDVTKPKPSYLLEIIERSFR
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MDITMLTVVQQKAIPCIMQGKDVLVKSQTGSGKTMSYAIPIIEHLQSTEPKISRTYGPYCIVVVPTRELVLQSYSVLMNLVRPFVWVVPGYLMGGEKRKSEKARLKKGMNIIVTTPARLVDHLDNTSSLSLDNLKHFVVDEADRLMFDMGFERDLSHIMLVIKKKCGPQLQTILLSATLSPGVEKLAGMSLRQPVRIDMSSNDQQGNHLPDGKVDDVFVTPSSLKHHYVVVPSKLKLVTLASFLLWKCQLSSNPSKVIVFLATQDSVEFHHTLLQTTFMSPEDDDDACKDFELFKLYGNMQQKDRTKIFQDFHAAKSGVLLCTDVASRGLDLPNIGWILQYNTPGSPTDYIHRVGRTARMGSKGNALLFLEPSEVEYVQVMTQHNIAMHEVKMDSILKTLLLESKTGKINLIHKPRTVEDAAAFMQAQFEESLCQNMNMRTLARKAYQSFVRSYATYPASLKHIFHIKNLHLGHLATSFALSETPSRLSETVRKFCQRERKISSRFFGSKGKKNFKDSKGKKNFRDSKSERLPHWIDKKFEDKFVGHQPSKRLVRELIKFRSIHYCFFNSNCWIVKLMAFQ
The following text describes a protein:
Function:
Probably shows dehydratase activity.
Miscellaneous:
MISCELLANEOUS: Contains a dehydratase motif that is predictive of enzyme function.
Sequence:
MTTLKLDTLSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIKHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREEVAERRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAMAENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGHDATSGKVFLPQEKALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRKAHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVAGYSAFFTALSPDAQDDIIARTEHML
The following text describes a protein:
Function:
Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.
Sequence:
MGSLRAILKNPDDLYPLVKLKLAARHAEKQIPPSPHWGFCYSMLHKVSRSFALVIQQLPVELRDAVCIFYLVLRALDTVEDDTSIPTDVKVPILISFHQHVYDREWHFSCGTKEYRVLMDQLHHVSTAFLELGKHYQQAIEDITMRMGAGMAKFICKEVETTDDYDEYCHYVAGLVGLGLSKLFHTSGKEDLASDSISNSMGLFLQKTNIIRDYLEDINEVPKCRMFWPREIWSKYVNKLEELKYEDNSAKAVQCLNDMVTNALSHVEDCLTYMSALRDPSIFRFCAIPQVMAIGTLAMCYDNIEVFRGVVKMRRGLTAKVIDRTRTMADVYGAFFDFSCMLKSKVNNNDPNATKTLKRLDVILKTCRDSGTLNKRKSYIIRSEPNYSPVLIVVIFIILAIILAQLSGNRS
The following text describes a protein:
Function:
May be required for pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MANRTLKDAHSIIRTRICESKYWKEECFGLMAELVVGKAMELMFGGNIKPTHFLCLILKMLQIQSQKGITAEFIENEDFKYVHMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKNEFIDELVHRERVCDIILPRLQKLSALEEDIDDVESSEEEEEEDEKLERVPSPDRLRRSYGDLDKPRPSPTLCYRRSRSLSPRRRNRSPKSRSPFSRRERHPSKGPRHHRSRSRDRRHRSRSKSPDPHRSHRHRSHSKSPKRSKKSHEKSRRGNE
The following text describes a protein:
Function:
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
Subcellular Localization:
Mitochondrion outer membrane.
Sequence:
MTEFSVAIIGGGLVGSLSAVYFAKRGYTVTVYEKQSDIRQSQKVSGRSINLALSARGIAALQSAGVYKSIAETLIPMQGRMLHDSNGTLSSQQYGIHGEFINSVDRRFVNEELLNAAEKYSNVKIYFEHSVVSCDFNNRTMIISDSTGQNITVHANLIVGADGAYSRVRTELLKKTIGFYSQEYIDHGYVELTMPATHSGNYAMDPGHLHIWPRQTFMMIALPNVDRSFTVTLFMPWFKFEEIQTPTQLIEFFEDKFADAVPLIGKGFLVQEYFKNTKGSLVSIKCKPYHYKDRAVIIGDAAHAMVPFYGQGMNCGFEDVLILDNLFSKHLDTLSISIDSHDDRKVPQLEMFTLSSISNMYVMSAPTPSQLASILKEYSTIRNPDAEAICDLALNNYIEMRSSVTTWSYLLRKKFESAMYALFPNLITPLYTMVSFSRIPYSEAMRKWKAQTWWYRTVGRASIWCGVLGVGVYALLRTPHVRKAIVSVLDY
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression.
Subcellular Localization:
Nucleus.
Sequence:
MINVMDHVNKPMNEVDKSLDGQLWHACAGGMVQMPELNSKIFYFPQGHAEHAAAGNGGFREFPRIPPYILCGVSTVKFMADSDTDEVYAKIGLVPLGNHSDCDFENDGFLGFDHIKNENQEKPASFAKTLTQSDANNGGGFSVPRYCAETIFPRLDYTAEPPVQTILAKDVHGKLWKFRHIYRGTPRRHLLTTGWSNFVNQKKLVAGDSIVFLRADNGDLCVGIRRAKRGIGRGFHDSNSSGWNTSIPGYGNSGKVSAESVIEAANLAATGRPFEVVYYPRASTPEFCVKASTVKAAMRIQWCPGMRFKMAFETEDSSRISWFMGTISSVDVDDQIRWPNSPWRLLQVAWDEPDLLQNVKRVSPWLVESVSNMPSIHLSPFSPPRKKLRTPQPSDFPHLSIINNHIPGSIQGARHNPQFQFGFDHYHQQQYFNKIQSFPFGSPQFPPTRFIQAAQETDENVSCLLTIGNSSNNSKSKTRSNEKAENKPTFVLFGQPIFTEQQLSDSSSGDTMANQSDGSVVVQNDSSSDEAEQKSEFGVETGHCKIFMESEDVGRTLDLTAFHSYEELYRKLADMFCIDKSVMLNSLIYRNADGSVKRTGDEPFSDFSKTAGRLTIVMDSGSDNVGV
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MPMPRSSGDSTPRIFRVFFQRLLGFVIVGAALGGSIMDSSGNELLQLKRYVATPTGKNVAQYYALIDVLKSAQSIGAFLHGLSGGSSFLSPTFLILDQGILEGLYEGYEGRVIGLIDSFESFDIRTTRTGKPMFHCVICLEDVQDADMYTLTECSRKFCSSCVKQHVEATVTTGRTFPVACPQVECTKKFTESECKKLLSEAALKVFMKKIEEERIPERMEHANASPAKRKRGEGDSKQALLYWLYGSSCAACKAARYSANVEALASVKKAHLDGHHGWALGASGDTVGDTAASPADMGCATSATSPTRVPAGDPSTPPLRAPVPLLSLTEEACKLLRASPCSADRDVFIFQQPLIRVITHKMPANDKFDFEQQIKPWMKRAVTRMIQPVRLSKDAYQAEPCGDEYGELQDRTHMSAVFTGIRSIMPTSEQIAARESSTKYMEEVRKADGSFEYVEKGVTPPPQDSNAAHESSSEKQNLRWVMDILMFALVGGAWCVDGVATWVPRVIAECKWSLKPEDVYQVALGGARLFVDRLQKRLPIDRLYLKVWSAKKYRYSILDVFGYVRLKNGRVTPESFSIFEKQVSELRRRCGDSFQEEAFKDASTSVQDMERLFQEREMEFQARFCGIRLPTEIVAPVGVLYISQDSRPFPTGSEVVEEKDAYVFYQGMLRALGSNAILGWEEEQLETSNSEMRIKKEESSGSG
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Catalyzes monoubiquitination of 26S proteasome subunit PSMC2/RPT1.
Sequence:
MASYFDEHDCEPLNPEREARNNMLLELARRVRGAWSWAPGSRSLFNRMDFEDLGLVDWEHHLPPPAAKAVVESLPRTVIRSSKAELKCPVCLLEFEEEETVIEMPCHHLFHSNCILPWLSKTNSCPLCRHELPTDDDSYEEHKKDKARRQQQQHRLENLHGAMYT
The following text describes a protein:
Function:
Required for ESX-1 function. Required for the maintenance of adequate cellular levels of both EspA and EspC. Facilitates EsxA secretion.
Subcellular Localization:
Secreted. Note=Export does not exclusively require ESX-1. May require one (or more) of the other ESX / type VII secretion systems (T7SS).
Sequence:
MDLPGNDFDSNDFDAVDLWGADGAEGWTADPIIGVGSAATPDTGPDLDNAHGQAETDTEQEIALFTVTNPPRTVSVSTLMDGRIDHVELSARVAWMSESQLASEILVIADLARQKAQSAQYAFILDRMSQQVDADEHRVALLRKTVGETWGLPSPEEAAAAEAEVFATRYSDDCPAPDDESDPW
The following text describes a protein:
Function:
Hydrolyzes ribosome-free peptidyl-tRNAs (with 1 or more amino acids incorporated), which drop off the ribosome during protein synthesis, or as a result of ribosome stalling; Catalyzes the release of premature peptidyl moieties from peptidyl-tRNA molecules trapped in stalled 50S ribosomal subunits, and thus maintains levels of free tRNAs and 50S ribosomes.
Subcellular Localization:
Cytoplasm.
Sequence:
MSQPIKLLVGLANPGPEYAKTRHNAGAWVVEELARIHNVTLKNEPKFFGLTGRLLINSQELRVLIPTTFMNLSGKAIAALANFYQIKPEEIMVAHDELDLPPGVAKFKQGGGHGGHNGLKDTISKLGNNKEFYRLRLGIGHPGHKDKVAGYVLGKAPAKEQECLDAAVDESVRCLEILMKDGLTKAQNRLHTFKAE
The following text describes a protein:
Function:
Catalyzes the final step in the synthesis of long-chain linear esters (waxes).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MEEELKLFIQVWVSAIISVTYCYYLTPKIKTSLLRLLSVLPVCVLFLIIPIFFSTVHSSFTIAFFLSGLAVPKLILFALEKGPLFPLPPNLPHFVCFACFPIKLQKKPNPENTNHFPKWVFALKVFIFGALLLQAYHYKQFLSTNFLLGLYALHIYLELEISLTLIKFLVSITLGCDLEPQFNEPYLATSLHDFWGHRWNLMVSKILWLAVYNPIRQWRAKSSEWDRFFAIFATFLVSGVAHEILYFYLTREKPTWEVTWFFVLHGFCMAAEVALKRKTKLVQRWPVNPAVSRLLTVGFVFVTGVWLFSPQPIRHGLMERFINEDLFLIDFFNRKLYILLGLFTSL
The following text describes a protein:
Function:
Magnesium-dependent guanylyl cyclase that catalyzes the formation of guanosine 3',5'-cyclic monophosphate (cGMP) from guanosine 5'-triphosphate (GTP). Can also use ATP as substrate with a low activity.
Sequence:
MWPLCFLLNKLLRVEERNQGILDGNGDSTFPKYCLFDDPLVSDGKYRDAGLPSSSHMDVPHVHQLASWDCGLACVLMVLRASGIASCTLEDLAEICSTNSIWTVDLAYLLQKFCVEFSYYTITFGANPNYSIEEFYKEQLPEDLVRVDLLFRKAHESGIIIQCRSVSIHEISCLLLSGNYIAIALVDQDKLSKSWLEEVLVSGLHSSNSCYTGHYVVICGYDAVRDEFEIRDPASSKIHERISSKCLENARKSFGTDEDLLLINLENMRNQNGY
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MPPRRKSTDQHDLVERPSRKRPLPADPYEVPDEDDAVPSAKRQRRQPEDGGTPSKRNATPRKQVDFLQRDLASVPEEPESPTEQTPSKKRIGRPPKAKTGGTPSGKPSTPSALRKKQVDETPIKLKGISGVDTPGRRGIADRSARRKSARALIDRVLEGAVSDDEDEEQQIAREIYESSEEEEEGDTQQENLADQEAELAATTPSKTGRGRGRGGRPPGLARRKKSPTPPRDLPPHEQYFYQNKPGSNKTSNNTLSSLDLLIHEEYFSLLRNLGQDPHEKHIDALQSQHAASFPQWAFELSQGFSVCLYGYGSKRRLLHQFAEYLFSSSGGNDTNNTTIIMINGHTRTLTFREILTTISAAIDPTFRLPSGNPLAMIQNLFTLLSSFAQKPRITLLLASLDSPFSPLRKPQTQSLLAHLSSHPAISLACTVDTPDFPLLWDSSLRSSFNFAFHDCTTFADHSKELDVVDEVHELLGRMGKRAGGKEGVAFVLRSLPENARKLFGLIVGEVLVAFEDGGGGGGGTSGAGDFAAGGEGPGVEYRMLYNKAVEEFICSSEMAFRTLLKEFHDHQIITSHKDSIGTEYLSLPFRKEELESILEELMS
The following text describes a protein:
Function:
Component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis. The MAC is initiated by proteolytic cleavage of C5 into complement C5b in response to the classical, alternative, lectin and GZMK complement pathways. The complement pathways consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Together with component C5b, involved in MAC complex assembly: complement C5b and C6 associate with the outer leaflet of target cell membrane, reducing the energy for membrane bending.
Subcellular Localization:
Secreted. Target cell membrane; Multi-pass membrane protein.
Sequence:
MARRSVLYFILLNALINKGQACFCDHYAWTQWTSCSKTCNSGTQSRHRQIVVDKYYQENFCEQICSKQETRECNWQRCPINCLLGDFGPWSDCDPCVEKQSKVRSVLRPSQFGGQPCTEPLVAFQPCIPSKLCKIEEADCKNKFRCDSGRCIARKLECNGENDCGDNSDERDCGRTKAVCTRKYNPIPSVQLMGNGFHFLAGEPRGEVLDNSFTGGICKTVKSSRTSNPYRVPANLENVGFEVQTAEDDLKTDFYKDLTSLGHNENQQGSFSSQGGSSFSVPIFYSSKRSENINHNSAFKQAIQASHKKDSSFIRIHKVMKVLNFTTKAKDLHLSDVFLKALNHLPLEYNSALYSRIFDDFGTHYFTSGSLGGVYDLLYQFSSEELKNSGLTEEEAKHCVRIETKKRVLFVKKTKVEHRCTTNKLSEKHEGSFIQGAEKSISLIRGGRSEYGAALAWEKGSSGLEEKTFSEWLESVKENPAVIDFELAPIVDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPTLSGTECLCVCQSGTYGENCEKQSPDYKSNAVDGHWGCWSSWSTCDATYKRSRTRECNNPVPQRGGKRCEGEKRQEEDCTFSIMENNGQPCINDDEEMKEVDLPEIEADSGCPQPVPPENGFIRNEKQLYSVGEDVEISCLTGFETVGYQYFRCLPDGTWRQGDVECQRRECIKPVVQEVLTITPFQRLYRIGESIELTCPKGFVVAGPSRYTCQGNSWTPPISNSLTCEKDTLTKLRGHCQPGQKQSGSECICMSPEEDCSHHSEDLCVFDTDSNDYFTSPACKFLAEKCLNNQQLHFLHIGSCQDGHQLEWGLERTRLSSNSTKKESCGYDTCYDWEKCSASTSKCVCLLPPQCFKGGNQLYCVKMGSSTSEKTLNICEVGTIRCANRKMEILHPGKCLA
The following text describes a protein:
Function:
Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Binds RNAs which might negatively affect its histone methyltransferase activity. COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face.
Subcellular Localization:
Nucleus. Chromosome.
Domain:
The RxxxRR motif forms an adapter helix that bridges the nucleosome and ubiquitin.
Sequence:
MGTIWLISAASDDQDDAPPSDPRLAKGGRLNYINVDFHLPKARLRHAPYNLKPYKYDPKTSCGPGPPTQVVVTGFNPLIAFSKVTAVFASFGDIAESSNKMHPDTGSYLGFATFRYRDSKPSRSRPISITGADAAKRAIRAMHGKRIEANMVRVEYDAEGKKSSRMLVEVLQKGNETTPALGEPRIPTGPKPKEVAPGPPPTAPKGPAAHRGGLMNVQGVWVPKPRPDSIIEVEPVIGHLKHDPYIFVGHEHVPVMPTTVAHMKRRLKTYMFEDIRADRTGYYIVFQDSGYGRAEAERCFRSADRTAFFTYTMVMVLHLYGTDGKASHAHASDTRRRTRTPERKHVDEARPHREHDRSRRDEERARRDEQDRRRREDEADLEEEKRQRAKNYDPVLEATDVVLRGMKEQLIKIIRTKIAAPALFNFLDPVNHLAKRRRLNLEDPHSARLPPIVLDEFEDRSPVSTPNSRADPIERRTARLDVSALPRIRKVKNAGLNTRKHGFNDPFARNRPTARRTAFRSLHYRLRSDSEGESEDEAENRTSLGRDTEEPESRPRSRMSSDDEGDKDDYASWGPGDDDSMTEASFALGDGPGLAKKRKLDLQVETAIKRQKKTDEELFGVTIDRIGTEFPSREDSLEDVLPPGPGGGEEKDIGSSRLPTPLLQEGKAKKKAPAKTKRKSKKQLFEEREALKRQQQEIFEREALQSEDVDEVIPTPEPESEPKKSKVEKEKEKEEKVEKPALDENLYPSQKVSVLELPHDFRLDVGSLEELALGPNDQPDLDRLRKRFGRGKIDDPELWVWRRDRIRELNSTDGSAKTPVRIEGYYVPNPTGCARAEGVKKILNSEKSKYLPHHIKVKKAREERQAQNGKNAKDSVLAAAEAARLAAESLVAKGNSRANRANNRRFVADLNDQRKTLGQDSDVLRFNQLKKRKKPVKFARSAIHNWGLYAMENIPKDDMIIEYVGEEVRQQIAELRENRYLKSGIGSSYLFRIDDNTVIDATKKGGIARFINHSCMPNCTAKIIKVEGSKRIVIYALRDIAQNEELTYDYKFERELGSTDRIPCLCGTAACKGFLN
The following text describes a protein:
Function:
Part of the ABC transporter complex PstSACB involved in phosphate import.
Sequence:
MATIRNKEISKTGGVCLSFVAVLAIAAATLFTSGKPVEELSENAAVGRKSVITAAGATLPLPFYSEAFKMYWEKNDIPVTYAGIGTERGFRSLKNQQIDFAGVDVPPTKAELDSLPVKSILVPTCMGAVTIAYNLEGVDNLRLTGELIADIYMGKILKWNDARIAAVNAGKQLPDKEIYPVFRLDGSGTTYIFSDYLTKVSTDWKAKIGTGKALTFPRGVAATGNTGVAGLVGKVPGAIGYVASEYAASFNTQSAWLKNAAGNFVQPTSESVTAVASVGDATGMITDSEVADAYPISCFTWVVLYKEQNYAGRSRSEAEETVKLLEWLISPEAQTITTQVQCSPLPEKAVEYAKNMLKEVTYDGKALRK
The following text describes a protein:
Function:
Required in both the follicle cells and the germline for oocyte development.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKIPGSNLEFVREEDFVEYYIFPKIPDNVQDEGALRKLMLQIRNEISAIVREKSLERSYLWHKDEFQLQVRLGGAEERLLNEETNPEEEAELGDLPPHFHGVTHYGDNISDEWFVVYLLTEITRARGDCIARVSDSDGEFLLIEAADALPDWASPETCEQRVYLVGGHLQLLQNSAASSQDKPLTMAMAVQRIRMNPTLYRCSQEIQSCIDARLKEYQIAQPHFSIHRQVLELPHSAAQLLKQKPRLLSSAVRAFCERDSLDIKALRTMRYFPPEATRVRTNVRFTRCLYAMLSHQQYLPEKRLGWHLTDPVSEPERYKEQLLGLKLASGLEILATQAKRVEGQQLEDLPAWRSYLRSLLSKGYFRDNIEGSAEYQELLNKAKVYFRGNQERFRTASRAGAEILDLLLHPAEAASEELRDEENNLQPSDSDEWLNISAEDLDSMLQDRYGPKKLYKPNGQMNAEEFTKQLAEFLDRQSNYEGIEHRGLEEPELDSDDDEPPPQANGSTGLTAKVKKNPSMRKACQRNSVIQPEEPDSTHVRNFLDFVIPEDNWDSTSEMSDYADEDDMESNLNALSGGGSVFPLDRQIQSYMEQMDRELAQTSVGKSFHGKKKTAPQADEDDFDDIEDFEPININVNTLRNMMDSYQSQVGGAGPVSNLFSAMGVGMSAVEDKEQKDISESAV
The following text describes a protein:
Function:
Chloroplast translation initiation factor that is essential for the coordination of leaf and chloroplast development. IF-3 binds to the 30S ribosomal subunit and shifts the equilibrium between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAVDCCISLPPDDDCNGECANADEDELNNEFSLELPRYDAMAAVTGTFAFKPVLTSFTATPATSAAAAVAAASPPLSLSSLESSKLFGVRLPEATGLARCSLVLAPRGGSVACRYGGGGGGGSRFSGSRDWRRSRQSDSEDDQALDMSTIRSATVRLIDQKQDMVGVMSKSEAIKMAEDAELDLVILSPDADPPVVRIMDYKKFKYEQQKKKREQQKKSAASRMDLKELKMGYNIDQHDYSVRLRAAQKFLKDGDKVKVIVNLKGRENDFRNNAIELIKRFQNDVGELATEESKNFRERNMSIVLVPNKALLQKGQEPPKKPDKSSANEVSAGI
The following text describes a protein:
Function:
Involved in root nodulation. Required for root nodule organogenesis after infection by symbiotic rhizobia. Probably not involved in arbuscular mycorrhizal (AM) symbiosis. Acts downstream of CCAMK.
Subcellular Localization:
Nucleus.
Sequence:
MGSNGTEEITSDISTGNAATTIEIKIKMLDSQTFTLRVDKQMPVPALKAQIESLTGVMSERQRLICQGKVLKDDQLLSAYHVEDGHTLHLVARHPDLTPPGSLPNHSATEPNSSTGHGYSNQVAPGVFIETFNVPVQGDGVPSEINRIVSAVLGSMGLPNFASGGEGIFVREHDSTGLGRTSDFTGNPSRPQPEQAGFRISSDSSRNSFGFPAAVSLGSLGSLQPPVIPDSLTTLLQYLSHINHEFDTIAREGGNNVQAAEAHRNEERGFVSSRLSSTPEGLSSPASLAEVLLSTRRVIIEQAGECLLQLARQLENHADIADPLSRSSTQSRALRTGVMFYNLGAYLLELGRTTMTLRLGQTPSEAVVNGGPAVFISPSGPNHIMVQPLPFQPGASFGAIPVGAAQSNSSLGGGLGSSFFPRRIDIQIRRGASTTPGTNQEEHGDTQSASVQRNTGESSVNQTTSRRPDASIAGEPGVRVVPIRTMVAAVPVLGRFQSSVNTNNEQGSQPASQQHTAPHSTAEFTLHRQSMEDSARNGTLPTPNTQQEPSSSRVVNINILSAGGPENNESERQVPSSVLQFLRALFPGGEIHVEDPSSQGTTAGVTSAATSSGAAQAPEAEPNVSEEGIFLSNLLRGIMPVISQHIGRGGDSSEDQVTRDPSTQVEIGAGTSRRQSDSESSPPNSKRQKME
The following text describes a protein:
Function:
RNA-binding protein which plays a role in sporulation. Regulates the progression of meiosis I and may function in the vicinity of the Mei2 dot.
Subcellular Localization:
Cytoplasm.
Sequence:
MNGIITPQKQKQLMSSPSRDPLSTTELSTPTSQTTVDVNDTKKSEGLDSTIILLTPGTSPNATPGSSELGLSKKPNSIKNNTYSTAAQAAYLNRRAADQSTVMTTDPISYANNNINNGTLPQQNAYYANSYYPSYYAQSQAISNNRPGVSGFRPAFNSVAPCYGSQWQTHQSVHPYHVNNTHQYLKPYVQNVYPQMPSLNQPGLHIVNQPTYLAPVPSATVPTNSVSLSMPSFSQGQKNIPAAINQEMSVGTTKENTNYLSQLVGLHPAIPPAIPSMFPMSHDNKKSNMESTSRTRNVYIRGLPPNTSDENLLLYTNRFGKVSSSKAIIDMETNLCKGYGFACFEEEKSALICISAMTLCGYQCSFAKESFSARLQSLQDTESTNLYISNLPLHWNESDISTLFKPSKIISNRVLRDSKEQSRGVGFARMQDRKTAEDIINKFNNFVLDPALPPLQIRFADSTDQKKFKGQTQKRRLWRAREYSVLTKGMTANNAFSKVEEFANNSMPSKVGMYVPLESNTVYQHSPTYDTYGWQSMYPSYSVYPSNYENSRSTTPYHAHPATSAAN
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Independently of its E3 ubiquitin-protein ligase activity, acts as an inhibitor of CPSF3 endonuclease activity by blocking CPSF3 active site.
Sequence:
MKSGSESVEVLDLVALSTNAYKSQGKMFHPIIGQDYRVQCAECQSVLINRSNFKRVLPLPRSSWSEAASDWYCHRHEGDADHQLVPRSTDCLFGSCYHALTTSLLIEGSLETAGRELLCSKCQASVGLMEEGLMNVWCHSIKWFLLEENDQWKMIEDVTTPLQAFYFTLYDALEEEKSFFGRKLAFRDGVGGGQTLLLWFVGDNGFTLDSKKSASEIELRQSSLHKVLYKSENSTSKKIPNDVIEYQVSRDMMNSALSVLRNSSEQLPPGCRTAAGFSIGYLSLSS
The following text describes a protein:
Function:
Required for cell division and chromosome segregation. Binds to DNA and is involved in segregating the origin of replication (oriC) region to new daughter cells (By similarity). When the nucleoid is not properly segregated, involved in blocking the cell division to protect the nucleoid against premature truncation by the newly forming septum, a function which is dependent on CpsD and its autophosphorylation level.
Subcellular Localization:
Cytoplasm, nucleoid. Cell membrane; Peripheral membrane protein. Note=Localizes at mid-cell at first and then at the future site of division as the cell elongates. Forms one or two bright foci per cell mostly around mid-cell of small cells. Localizes toward the center of the daughter cell as the cell elongates. The bright foci mostly co-localize with origin of replication (oriC). During the cell cycle, very faint, but highly dynamic foci are homogeneously distributed all around the cell periphery (By similarity). Co-localizes with CpsD at mid-cell only at the early stage of the cell cycle.
Domain:
The N-terminal DNA-binding helix-turn-helix (HTH) domain and the C-terminal membrane-binding amphipathic helix (AH) are both required for the function in chromosome segregation and for its proper subcellular location.
Sequence:
MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVTRSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSEKDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARLFGG