lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Subcellular Localization:
Secreted.
Sequence:
MSLALLCSLLLVHGSLGEIVFRCPSCTAERQAACPKLTTSCEIVREPGCGCCPVCARQKGELCGVYTTRCGSGLRCYPSANSELPLEQLIQGLGRCENKVDLEPTMTNQESAAHSGEVNGTRSPPMKKPGKDYQYIKEIAVNKHHNNKRTRMYNTQDDPKTPHPKQSQCQQELDKVLENISRMAFHDNKGPLENLYDLKFPNCDKTGQYNLKQCHMSTHGQRGECWCVNPYTGVQIPSSDKVRGDPNCSQYYGGPELEPPTAQQK
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) of multiciliated respiratory cells and the distal singlet microtubules of monoflagellated spermatozoa. Forms an extensive interaction network cross-linking the lumen of axonemal doublet microtubules (By similarity).
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, cilium axoneme. Nucleus. Note=In caudal sperms localizes onto sperm head. Is also present on midpiece and principle piece of sperm tails. Acrosome and sperm tail localization is regulated by Y-chromosome.
Sequence:
MNEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSSTDRRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPLILDLMKEWIAHSEKLPRKVLQHVSEPQAHQESTRGAARPAQAIGTQPRATKHKCRQLTKASLKPRGCSKPPWRPPGGKL
The following text describes a protein:
Function:
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MKLALLQTFLWCFFSVVVNVSFVLYRRLTYRLVGKVQVLMELWKSKVVLVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRADTLFSDNCSGAVYIRDIILRQGLVGISKTSVPTLTRSAEVALFAGFNPMPSILPTSNFDTIFNRTLAFDKGAFLRFSHLSDLRRRLTKRACLEKLWYANKLVMLVNLAEVGGASPLDIGFQMKLHNTQRNIRDAYELIEATFNDSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTENITSDFVLNNGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHLNALQLLTQAKAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKVALKSLKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQNVMAPHYMRRGYLTWCTIFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVWCMTLAALPQNGGWIFEPLKHLRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRGWLHPSPKFLAWLALVLLLGGFLWSQKGMQILMTTNYRVVLQAISMLVVIVRPCVLNENHKWKVWVINGGILFVAAIGIFLKEMGKPVPLYLFAANWAYLIYAFASVPCSSRTTPQSRLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEVHEKFKEADEDVKILTSSKHLQMCYRFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLIPSIVIMASVVALSSFGRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHPSVVHALLAQLTVILILACESIVTIFFRRLNMNRCSDWRQEADEFESSYPPITTTAV
The following text describes a protein:
Function:
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
Subcellular Localization:
Periplasm.
Sequence:
MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
The following text describes a protein:
Function:
Binds retinol and different fatty acids.
Subcellular Localization:
Secreted.
Sequence:
MYHRLILLALVGTTMANVIPFSMNNIPEEYKEFIPEEVRNFYKDLTVEDKEILRELASKHATFANEDAALEALKDKSDKLYKNAVELRNFVKAKIDSLKPDAKIFVDEIIAKARSLRSDDGHKLDTEKIKQAARDIIAKYQALSEETKEELKVTFPAIAKIIGNEKLKRNASTFLQKN
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.
Subcellular Localization:
Nucleus.
Sequence:
MFCSLFEMDNNNYQQAGDLTDVIRLSSAPVAGHFSSEFSLDPFSGDRQLWSHLPADNSSMNFGDPLSFPTRDPFLLPHFSPFNFASDGGGEGLAADDQPSNLLSHMLQISPSSGDGVISTPPCESLATAVGNSPRSTSVRGGGGLVLPTGGSNSLCLMENSGIQISSPRNSANKRRKSQVKKVVCIPAPAPANSRSSSGEVVPSDLWAWRKYGQKPIKGSPYPRGYYRCSSSKGCSARKQVERSRTNPNMLVITYTSEHNHPWPTQRNALAGSTRSHPSRTTTATTANKTSPKHERINDILPTTTIKEEEMDEDQMTDKATTTNDNQEEGDHQDFPYDLIFTEFADQMNDLEHDNNHDHNHHLSADPLNNNMLMFSNHGFSAGNGEGSKDPFLELYDWAENSSGSLFKEAKGG
The following text describes a protein:
Function:
Haemagglutinin that facilitates the adhesion to and invasion of epithelial mammalian cells. Utilizes heparinated proteoglycan as a receptor to successfully invade host cells.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Domain:
All four putative extracellular loops are crucial for invasion of mammalian cells.
Sequence:
MKNFFAVCIIPLVVAWSATASAKEGIYITGKAGTSVVNVYGINSTFSQDEIVNGHATLPDRTKGVFGGGVAIGYDFYDPFQLPVRLELDTTFRGETDAKGGQDIIAFGDPVHINVKNQVRMTTYMVNGYYDFHNSTAFTPYISAGVGLAHVKLSNNTIPVGFGINETLSASKNNFAWGAGIGAKYAVTDNIMIDASYKYINAGKVSISKNHYAGDEHTAYDADTKAASNDFMLGITYAF
The following text describes a protein:
Function:
The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MDTIEAKTVLISSEKISPLTYPDCDDDREQDIDDLIDELESQDGLHDNPSRKSMDSGSRIPGMEAQFDTDITTGLTSVEAAQRRKKYGPNQLKEEKENMLKKFLSFFVGPVQFVMEGAAILAIGLRDWVDFGVICALLLLNATVGFIQEYQAGSIVEELKKSLALKAIVVRDGRVTDIDATEVVPGDVLKIDEGTIVPADGRVKTNHLLQIDQSSVTGESLAVNKCKGEVCYASSVVKRGHAYLVVTATGDYTFMGKTAALVKSASSNSGHFTEVLNRIGATLLVLVVLTLIVVWVSSFYRSNETVTILEFTLAITMIGVPVGLPAVVTTTMAVGAAYLAKRQAIVQRLSAIESLAGVEVLCSDKTGTLTKNKLTLSDPYTVAGVDPNDLMLTACLAASRKLKGMDAIDKAFIKALPNYPRAKEALSHYKIQQFHPFDPVSKKVTAVVLSPEGQEIICVKGAPLWVLKTVSEEQQIPESVEKGYSDKMDEFAQRGFRSLGVARKPAGGEWEILGIVPCSDPPRDDTAATINEAKTLGLSIKMLTGDAVPIARETSRELGLGTNVYNSDKLGLGGGGDLTGSELYNYVEAADGFAEVWPQHKYNVVDILQQRGYLVAMTGDGVNDAPSLKKADTGIAVEGASDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMHAYVIYRIALSLHLEIFLGLWIAIMNESLNLQLVVFIAIFADIATLAIAYDNAPYSKTPVKWNLPKLWGLSVILGIVLAVGTWIALTTMMNAGEHAGIVQNYGKRDEVLFLEISLTENWLIFITRANGPFWSSLPSWQLAAAIFVVDLVASFFCYFGWFVGGQTSIVAIVRIWVFSLGVFCVMGGVYFLLQRSQTFDDIMHFNFLQKRDSVSQRVLDDLVVALQRRSEQHEQSSRTAEREDIGLWKMDKLRKERAQC
The following text describes a protein:
Function:
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAGLEAIKYGRGRLEVLDQLRLPHEFVYDNVSTCEEAFDSIKSMRVRGAPAIAIVAALALAVELHHEKDGSKTKQEAVQYINKRLDYLLGSRPTAVDLSNAIKLLKRVSQSAAEATNALDDSAACADVRKGYIDAAEKILEDDLTTNLAIGRYGAEYLRRQQMPIGGEEDDEDPSKFFTTSPPCTQGAPDRTYRKLSVLTHCNTGSLATSGHGTALGIIRSLHKMNYLDHAYCTETRPYNQGSRLTAFELVYEKIPSTLITDSMAGALFARMKESKNISAVIVGADRVARNGDTANKIGTYSLAVLAKAHNIKFIVAAPTTSIDLETVSGADIKIEDRAPTELTQISGAVVGKDGHVDVNTTARVAIAHQGIDVWNPSFDVTPSMYIDAVITEKGEVVRSSKGTFDFKTIMPERWAQQVEGKELSAETNVKAHVDDGTQFPMENI
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
Sequence:
MTSYQVSSRRYRPNNFSEILGQDIVVSILKNSLRLNRAAHAYIFSGIRGTGKTTLARVFAKALNCQNPTQDQEPCNQCAICKEISLGTSMDVIEIDGASHRGIEDIRQINETVLFVPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPVHVKFFLATTEIAKIPNTISSRCQKMLLKRISEETIIDKLATIAKQEGTETSREALLPIAKAAQGSLRDAESLYDYVVGLFPESLDPDSTAKALGILSEDSLYQLAEAITTQNYEQALTPVSDAMQMGVAPAHFLQDVTLLFRSFLLKQYSKQFHSVATKYSSEILLEILDFLGESARHINLALFEKTFLETVIIRLLRIYSRPTFSQLVSQIRQPAPTQIRPIPTASELESCPPQIKSSNTEETKSSPQPTAVAKLSQGSLLTTASSQTKKETIHQETLPPSLDKISPSESAAIDTLLQFAVVEFSGVLTKEPKHG
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
Miscellaneous:
MISCELLANEOUS: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTLWELFVAAILGIVEGLTEYAPVSSTGHMIIVDDIWLKSSNLMSEEAANSFKVVIQLGSILAVAIVFKDRILNLLGLKKNITSDQEQGHKLSIAQIAVGLVPAAVLGFLFEDYIDEYLFSVKTVAIGLIAGAILMLFADWVNKRKTATDTLDRISYKQAIAVGLFQCLSLWPGFSRSGSTISGGVILGLNHRAAADFTFIMAMPIMMGASFLSLVKHWDSLSSDLMPFFIVGFICAFVVALFVVRFFLRLINKIKLVPFAIYRIILGVILLLIMM
The following text describes a protein:
Function:
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons (By similarity).
Sequence:
MAEQISLVDVSSSVSLRGEDSSNVALLRDVFLPDVAASDPAESSVDVQDEHSSDDSDNENEVFPKQNDFSQRRRIQNAQFEALLSKCTDADSNEAFDRAPIALSDGELSIAHLVKKQDLGNGMLDPREYQIELFERAKTQNTIAVLDTGSGKTLIAVLLLRHTILNELDDRANGKTHRVSFFLVDSVTLAYQQAAVLRNNIDQNVAHFFGAMGTDLWDKRTWDKHLQRNMVIVCTAEILNQCLLNSYVRMDQINLLIFDEAHHAKKDHPYARIIRDSYFKAQPSQRPRVFGMTASPIDTKGDITEAATRLETFLDSRIATTSKITLLREVVSRPIEKVWAYNRLEPPFATELYKLMDTRYGNIKVLEGVYRFAWNASSELGKWCSDRAWWHALADDVLPKLEGNINKLIESNTMKAEHGAVFKDIIRIREASETVKNYFFTDPELPGELSPKVQRLRMELSKHFNDTTGTKCIVFTQKRYTAKILNELFTVLNIPNLRPGVLIGVRPGDIGGMNITFRQQFLALVKFRTGEINCLFATSVAEEGLDIPDCNLVIRFDLYRTLIQYVQSRGRARHCTSTYAIMVEKDNAEHEGRLKEIREAENIMRRFCEILPEDRILHGNDHDLDSFLQEEEGRRTFTVKSTGAKLTYHSAIAILARYASSLQYEKETVPQVTYVVTIASNAYVCEVILPEKSPIRGLTGSPAMRKAVAKRSAAFDTCLLLRKNRLLDGYFNSIYHRRLPAMRNAKLAITCKRTNAYDMLLKPSIWAKQRTTPTETFYGIHMSLLPSKPLSRDHRPILLLTREKLPEFPAFSIYLDEDVETKVLSYPLKHGLQISVDKLQSLTVFTLRIFRDIFHKVYEHEVQKMPYWLAPAEAIDGRGSGKNPRDCIDWDTVSFVHNNDEITFTRNLNPESLVNRFIFDNWDGRFRYFTVAVADTLQPSDPPPPSVPRRRYMNNIMNYTLSLSKNSRARFLSSCDWNQPVLQAELVRLRRNLLDKMTTQEKEMQTECFICAEPLRISALPPSIVSTCLAFPAIISRLDSYLIALEACDELELVIRPDFALEAFTKDSDNTEEHRGQQIHFQRGMGKNYERLEFLGDCFLKMATSIALFSQNPNDDEFDYHVNRMCLICNKNLFNTAIKKQIYRYIRSRGFSRHIWYPDGLTLLHGKDHSTKLLSEGKHALGEKTIADVCEALIGASLLSGGPEHRFDMATKAVSALVDSPSHRVSCWKEYITLYTLPKYQTEKHRGSEDDLARHVEEELGYHFTYPRLLASAITHPSLPSTWGYRVPCYQRLEFLGDSLLDMVCVEDLFRRFPDRDPQWLSEHKMAMVSNKFLGALSVKLGFHRRIMAFSNPLQAQITHYVEEIETAQAESQGAVDYWVVAKDPPKCLPDMVEAYLGAIFVDSKFDFQVIEAFFERQIKPFFEDMSIYDTFANKHPTTFLHNKLTNEYGCTNYCLKAGELPTIDGAPATVLAAVIVHGNVISEARSSSSRYAKITASEKALAVLDGLLPSEFCQKYRCDCKETKNSSSVVEIGTAI
The following text describes a protein:
Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. E2 ubiquitin conjugating enzyme that transfers ubiquitin to MAEA, a core component of the CTLH E3 ubiquitin-protein ligase complex. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A.
Sequence:
MSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFVVKFYGPQGTPYEGGVWKVRVDLPDKYPFKSPSIDLTNIFESFLPQLLAYPNPIDPLNGDAAAMYLHRPEEYKQKIKEYIQKYATEEALKEQEEGTGDSSSESSMSDFSEDEAQDMEL
The following text describes a protein:
Function:
Required for cell division and gliding motility.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSSNFDKFQKRRLISSYFSVVLSVFLVLFLLGVLGLFIINSKKLADDFKEKIAMTVFFKNEANDSIIKAFNSELKRAPFALSYVYVTKEKAAKEHTDIIGEDFLTFLGENPLLNSYDIHLKADYVERDSILKIESALRKNTMIEDIVYDKQLVNLVNDNIKKVSMWILIISGFLTVIAVLLINSSLRLSIHSNRFIIKTMQMVGATKSFIRKPFVMRSVKLGMLGALLAIIALIGLLFYVETNFPGLGILEDKALIGLVLLAVFGLGVLITWVSTHFATQRFLNLRTDDLY
The following text describes a protein:
Function:
Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.
Sequence:
MSGRSKGRRSSRAKGRGKSRAKGRVRAAPDDAPRDPDPPECQRLGEETKAAQVQAGAVWGGPEGAAPAPPRRPGEEAACRLPLDCGLALRARAAGTRGQAVTRPCLVKATSFPERLVSDTVFVGTVGTVARPRNGPRVGSRRGPAAKKAPDTCSAVGRGSAALAGGKPKKGPAAEAASVPVGEEKVENAGSGPPATEGSMDTLENVQLKLETMNAQADRAYLRLSRKFGQLRLHHLERRNLLIQNIPGFWGQAFQNHPQLSSFLNNQDKEVLSFLNSLEVEELGLARLGYKIKFYFGRNPYFQNKVLIKEYGCGPSGQVVSRSTPIQWLPGHDLQTLSQGNPDNSRSFFGWFSNHSSIESDKIVEIINEELWPNPLQYYLMSEGARAEKGKEGRPGPARPPGETPEPGPSRNPAGCWTDGQAGTCGHVLTVVKLWLQTCTEMERPRVPSPSYIIYQLWSTQFHLHLHLPACIVDRKSKTLCQFNWDHFGRLRHSAGGDRGGLHSHYRIRSAFCFSC
The following text describes a protein:
Function:
Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MAVPGEAEEEATVYLVVSGIPSVLRSAHLRSYFSQFREERGGGFLCFHYRHRPERAPPQAAPNSALIPTDPAAEGQLLSQTSATDVRPLSTRDSTPIQTRTCCCVISVRGLAQAQRLIRMYSGRRWLDSHGTWLPGRCLIRRLRLPTEASGLGSFPFKTRKELQSWKAENEAFTLADLKQLPELNPPVLMPRGNVGTPLRVFLELIRACRLPPRIITQLQLQFPKTGSSRRYGNVPFEYEDSETVEQEELVYTAEGEEIPQGTYLADIPASPCGEPEEEVGKEEEEESHSDEDDDRGEEWERHEALHEDVTGQERTTEQLFEEEIELKWEKGGSGLVFYTDAQFWQEEEGDFDEQTADDWDVDMSVYYDRDGGDKDARDSVQMRLEQRLRDGQEDGSVIERQVGTFERHTKGIGRKVMERQGWAEGQGLGCRCSGVPEALDSDGQHPRCKRGLGYHGEKLQPFGQLKRPRRNGLGLISTIYDEPLPQDQTESLLRRQPPTSMKFRTDMAFVRGSSCASDSPSLPD
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as non-selective cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHVIIHGNIAANESSDDKGIIGAILDKSSRIGQEHAVAMKLALEDFYQKSIQSFSLHIRNSQGDPLLAAIAAKDLIDNQKVQAIIGPQTWAETSLVAEISSQKRIPFLSLAEATPEWAMKKWHFLLQSSPSQIMQMKAIAEIVKSWKLYNITMIYEDGDSSSTKILSQLSEALTEFGTELSNAIAIPPLVSSSLSQQLEKLREGQCRVIIVHLSFPLALNLFETAKRMNIMGEGNVWITTGSFTSLVHSLNASTISNMQGVIGVKSYIPKLFPQYADFYRRFRKKFSSENFEEFNYEPGIFAAEAYDAARIVVDAMRETNQIGGQLLLDKIMLSNFTGLSGKIQFTKHGRAPAHTFKIINLIGRSYREIGFWSDGLGFSKYLDEKASYSSSVKELGKVVNPTCAIRLRIGVPSMSNVKQYAEVIQDLSQNVPSFNFKGFSICLFDEIVKKLPYRLEYDYFAFNGTYDELVKQVYLKNYDAVVGDVSIVSTRYEYASFTQPYTETGLMMIVPIKSKTGDRTWLFMKPFTKRMWILILFIIVYNGFVVWIIERNHRPEPEGPILQQTTTMLLLAFCSLFSLNGDRLHSNLSRVAMVVWFLVALIISQIYTASLASMLTVERSEPTVDSIQQLKNNNAIVGCDRGSYLQRYLQDALGINANKIKPFNSMESLAYALRNKEIAAVFLDVPQAKIFLAKHCKGFVQAMPTYKIGGYGFVFPRGSPLLHSVNQALLNISESGTLRDLENRMLASEKCIDIIDPDAKYTSLSPTSFMVPFFLTGGTSTIALLIYIFSANYLCHGQRTMWGLMMAVIKR
The following text describes a protein:
Function:
Glucosyltransferase involved in the biosynthesis of the non-bilayer-prone membrane lipid alpha-monoglucosyldiacylglycerol. This is a major component for maintaining a certain anionic lipid surface charge density, for balancing the bilayer to non-bilayer phase equilibria and for keeping a constant lipid bilayer spontaneous curvature (curvature packing stress). Catalyzes the transfer of a glucosyl residue from UDP-Glc to diacylglycerol (DAG) acceptor to form the corresponding alpha-glucosyl-DAG (1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol). It can only use UDP-Glc as sugar donor.
Subcellular Localization:
Cell membrane.
Sequence:
MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKDVNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGIWIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVRDLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISYEKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSETALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGEHDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKDDTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Sequence:
MTLLQLVREHWVHILVPMGFAFGYYLDRKDDEKLTAFRNKSMLFQRELRPNEEVTWK
The following text describes a protein:
Function:
Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light.
Subcellular Localization:
Nucleus.
Sequence:
MEGETAAKAAASSSSSPSRYESQKRRDWNTFLQYLRNHKPPLNLSRCSGAHVLEFLKYLDQFGKTKVHATACPFFGQPNPPSQCTCPLKQAWGSLDALIGRLRAAFEEIGGGLPESNPFAAKAVRIYLKEVRQTQAKARGIPYDKKKRKRPHTDTATPIAGDGDDAEGSGGAALVVTAATTV
The following text describes a protein:
Function:
Involved in degradation of methylphosphonate. Catalyzes the hydrolysis of the phosphate ester at carbon-1 of 5-phospho-D-ribose 1,2-cyclic phosphate to form ribose 2,5-bisphosphate. This intermediate is then hydrolyzed to ribose-5-phosphate and inorganic phosphate.
Sequence:
MIEDLHVHSTMSDGSDTFEQVLEQAAQRGVERLAFTNHDTTAGLTAARELGERLGVQVVGGIEVSAYDFERGRKVHILGLGVEEGAPALAALCGSTLERRHANSLWQLDRLVEAGYEVDVERALELGRASTCLYKQHLMAALTSEPYPSAAYRTLYRSLFKNGGICDRDIDYVDARDAVRVVVEDGGLAVLAHPGQLDSYDLLPDLVECGLGGIERFHPDHTLADHARCAELAVRYRLVCTGGSDYHGKFGRVPHVGFRVPA
The following text describes a protein:
Function:
Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.
Sequence:
MLSAAVCGNIFASPNSQQVTNGLEKLENGKGILIVVMNYTGDVLNFGIAKERWTARRNTDAIKMVVVGDDVSVGKEQGKLAGRRGLAGTVLVYKIAGALAAQGAPLSHVHAVAQFVADHSATIGAGFDHCQIPGAQANKEHDNLGSDEIEIGMGIHNEPGYKRQKIANLSQLISDLMPVLTSTTDKDRSFLPFRTQGSSSKEVSNDVILLINNLGSISELEMCAIVKSTGTWLLEKGFQVKRVISGTLMTSLDMSGFSISLVLLPPANEDVTIEIAGEPTLSISANMLLDLFDAPADCPGWKSGYAGQPSFSKVEKKDAKALVQEPAGGEQKPSEETVSVNDPALFIKAVQSACQALISAEPEITKYDTIAGDGDCGLTLKSGAEGILAAISQEKIKGTNLISDLLQISEVVNRDMGGTSGGLYSIYFNALAVGIGKAKPSKSIGSQTWADALDYALNTLYKYTRARSPSRTLIDPLSAFVLTFTLTPTEFDKAIEAAKESAENTIYLDAKAGRASYVDRQKLQDSQVPDAGAWGVWKLLEAIGQVIN
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MATSQGPAGQWSPMVIVEAAGGALPQVSQYSVKPANQEEDCLSFEDVAVYFSWEEWTLLDDSQRLLYQTVMSEILTLMSSLGLIPSGIHEMTQLKSWGEPSVPALRFLTPGCWIKVDSEMSPFEQSPSAEGARPSTLQQHMLCCAETPVLSMDNVMILQTSSGLLRHQVTYNVGDAPMNMESGEAIQSEKKNCICSDCGKTFTSTSHLNRHRMIHTGEKPFQCSECGMSFSQKAFLIKHFRIHTGEKPFRCGECGKAFKHNISLVSHQRVHTGETPFTCTECGKSYMTRSNLTRHFQVHAAEKPYSCSECGKAFKEKSSLIYHARVHTRERPFQCSECGKSFSQKAFLIKHFRIHTGEKPFRCSECGKTFKHNCFLVAHQRVHTGETPFTCTECGKSYMNRSSLLYHYRVHTGEKP
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MAHMQEEPRRSQSAVEFNPVSLYQAGQDIVQDIAQKAQEIFQALKLSQLPNGIATGQRNAQERINKLKDLLNKVEVLFKQLRVIYNECQKRVGDVEPNVNTLVPILKEIPNTEHEQALKSHKELVLQSRKKDLEMKLCMKNKQLETLVAQMTDFVWDINAALASPYGS
The following text describes a protein:
Function:
Toxic component of a toxin-antitoxin (TA) system. An RNase.
Sequence:
MKLLLDTNICIYIIKQQPVAVLERFLEYQVGDIGISSITLSELRYGVAKSTHMEKNAKALDEFIIPLELVSYDESAAHVYGDIRAALEKAGTPIGSMDMLIAAHAVSLGIPLVTNNTREFLRVPSLNIIDWTV
The following text describes a protein:
Function:
Promotes matrix assembly (By similarity). Involved in the organization of skeletal muscles and in the formation of neuromuscular junctions (By similarity).
Subcellular Localization:
Secreted, extracellular space, extracellular matrix, basement membrane.
Sequence:
MLPWTVIGLALSLRLARSGAERGLPASALQGDLLFLLDSSASVSHYEFNRVREFLGRLAALLPVGPGALRASLVHVGSRPHTEFPFGQHSSGSAVQDAIRAAAQRMGDTNTGLALAYAKKQLFAKAAGARPGVPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNLLELSAAASAPAEKHLHFVDVDDLHIITQALRGSILDAMWPQQLHASEVTSSGFRLAWPSLLTADSGYYVLELAPSTDPGAARRQQLPGNATGWAWTGLDSDTDYDVALVPESNVRLLRSQHLRVRTLPEETGPELIVVSHTRPRSLRVSWAPALGPDAALGYHVQVGPLRGGAAQSVEVPAGENSTTLQGLAPGTAYLVTVTAAFRSGRERALSAKACTPEGERSRAPRPQPQRTGGREP
The following text describes a protein:
Function:
Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
Sequence:
MVREDKATWKSNYFLKIVRLLDEYPKCFIVGADNVGSNQMQRIRMSLRGTGEILMGKNTMMRKAIRGHMENNPALEKILPHISGNVGFVFTKGDLKEVRDKILENKVEAPAKAGAIAPVDVYLDPLNTGLGPEKTSFFQALSIPTKISRGTIEILNKVYLIKKDEKVGASEATLLNMLKIFPFTYGLGIQYVYDSGSVFHPSILDITDDDILAKFMQGVQNVASVCLSIGYPTAASVPHSLANGFKNLLAIAAETEITFSQAEQMKAFLADPSAFQSAAATSAAPAAEAAKEEAKVEEEEEEESDDDMGFGLFD
The following text describes a protein:
Function:
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Domain:
Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
Sequence:
MGLFDKLKHKKHEPVEAAPAPAAHIASAPAADAETGAGAVEKDTPRFDSSKVTVVFVLGGPGAGKGTQCARLVQDYGFVHLSAGDLLRAEQQRPGSQYGAMIADYIKEGKIVPMEVTVALLSNAIAEALSKQATTEADHSIPEEHKLKWSDGKGRFLVDGFPRKMDQAIKFDESVCESKFVLFLQCSEEVMLERLLERGKTSGRADDNIESIKKRFQTFVETSMPVVDYYRKQDRVVEVDSIKTVDQVYAEIKEAMDRTFAKLEQ
The following text describes a protein:
Function:
Acts together with ptf1a to induce the pancreatic lineage within the endoderm.
Subcellular Localization:
Nucleus.
Sequence:
MNADDQYYPQAPIYKEPCAFQRSQGQDYNPSPPACLYMGRQQQAAYSNPLVALDPGSPPDISPYEVPPISEEPIVPHLHHHHYHHHHHHPGIPHPHHQMPFPDDNESGTLEERNRTLLPFPWMKSTKSHTWKGQWTDGSYIMEQEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGRGSDPEQDSVVSSADVLKDEPQCLGNSQKTGDLVLSSPLPTSSQPNQVPSIGSLRQAEKR
The following text describes a protein:
Function:
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
LQLDWKPTVTRLQLWRPLTAFLNFGPLGLGYLMTVHFVWTYMSTLERLNHNTPYDFWLMMLFGSVMMVAGYSMLGLSPRFLGHNLSTFLVYVWSRYHEGLEVNMFELFNTRAELLPWFFLAQTFLLEGEVPILDFLGIVFGHIYHHYKTTNVLKTPRFVIQWYN
The following text describes a protein:
Function:
May play a role in the trafficking of a subset of G-protein coupled receptors.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MIINSNIKITLEERSNKLEQSHIEIGLLIGQESEISEQQTFVLGLFPTPLNISNTDDDNNNKPINIDSISSIDKEWILEYCHQVNIMLYGGIDIVGIYMIIPDSDTLNEKNNESFIMKLLKSIHTIINSKSLQFISYSKKTGLINGKATNSTQLYRLKSTEIKVINNLENEFLSLHCILPIDIKLKSKNGMISFENLKKDIIEIFENQLFKESTLLIENEFVSGNEIISQQFKSKSKLNIDLLINQLDSISTSSLEFNFNNNNNTHCIAYIHQLEQIKTAFKFIKKDIIKSVESRFDLLFNEISSNNNNNDNDQDNIKLSKESPILELPRRVNIQWLSNKISICDYLSSNGTIDDCYKIINDLLQITSPKINSIESSKNNNNNNNNNNNNNNNNNNNNSKLSNKKENNEIKENKDTQSNLTKSTSQQQTKQTNNSYLIIIISVLVLMVAFYFKFFV