lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Stimulates specifically the GTPase activity of ypt2 and ryh1. Inactivates ryh1 during recycling between the endosome and the Golgi compartments (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNLLKHIFLEDDYDAYEGTLDPASFFRINKQEEIIASTVCEIGWEYSKSFGNAYICTSFLCFHSDDFKTRFTFPLAAVRKLERENSDNDTFTFDLSNFHSQIIHLRFKGTRQQSEFFCDRLVRQLHASLEDASSVGLFLLSLASERVCFSESANSQEIESIDLGLGSQFGYPIASSNTNGLINENNSKSWIQYLKKNGANFNLIQTPNFQKLVQSGIPNNLRADIWETCSGSLFPRWKSKGFYAKNIDSVINNRCEYSEEIEKDLTRSLPDYPAYQSPTGINTLRRILLFYSETNKEVGYCQAMNIVLAALLVYCTEEQAYFLFSQLCEFYIPGYYAKIIHGLLLDLTVFEYVLEHTLPHLYQKIIELDMDLKLITINWFFSLFIKDFRLDYAFRILDCLFVNGPRVLFQVALALFKVNAQGILNATDDSSVMKVFRQCFDHINQGTAADEKMAALGSRSSMCTLPQLFAVAFEYFDFITDSFVSAKRKEFKSSVLYSLRCFTKRSHLRSVYQTTLLSNTDLDLVYDAFINAIGENNICHGDVLEQKIDFNGFERLVDCAAPPLSVIREPLHYQRSKRKLFTRLYIWMKDGDSTETSLTFKRIIHGLERLKADIALHSEILCFQLYDLKRDGTLRTEEVVELSESLILLCCYEGDEKDEERLTVISEFLKSCFSGCQDRRSFQITMEDFQAIVDTTGLHATLEFFLKKLIDGLLGKLNAS
The following text describes a protein:
Function:
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Sequence:
MSRREKNPLEMFQSGHLVKICAPMVRYSKLAFRTLVRRYDCDLCYTPMIIAADFVRSVKARDSEFTTNQGDRPLIVQFAAKDAQLLADAATLVRPYANGIDVNCGCPQRWAMAEGYGACLINNPELVRDMVRQVRNQVEDVTFSVSIKIRIHDDLTRTVDLCRKAEATGVSWITVHGRTVEERHQPVHYDAIKIIKESLSVPVVVNGDVKSLREAETVQRVTGTDGVMVARGLLANPAMFAGYEETPLKCIRDWVDVSLEHGSPFTCFHHHLMYMMERITSKQEKRVFNALSSTSAVLDYLADHYGL
The following text describes a protein:
Function:
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
Sequence:
MHGVKRQPKTAATAEARAARKAKEAAKLAAYLEVEQTFFEYKRSARKDTTALHHTTKLLTLNPELYTVWNYRRQVLLHMFASSVEHGARQDVQKREVFASLGEHQEQQKDQEQQKDDTRQDKLTVKMESKQQLLEDDLALTEHALRAHPKVYWIWNHRMWCLTQYPTATSSSAPASSSSSSSSTNADADTDAATWLWERELKLVEKMLDLDARNFHGWNCRRTIIQHLALCILSADASTSELACTQPSFPTLLSEPAVVMRAAPAVKTKLVSLAENELAYALRKIESNFSNFSAWHQRTQLLPHVWAAKQLSVDQMHVYVDAEFERVKHAMYTDPSDQSVWFYHRWLVDITLAEQTPQQDREQHCITSHRQRKINVLHSEIGVIEELFELEPDSKWCAISLAHYNTLLATLYQGQTDTDAEHAIAQQASAKAKRLLQQLIELDPDREHRYRDLLQGNAHF
The following text describes a protein:
Function:
May be involved in recombinational repair of damaged DNA.
Sequence:
MLLQLNIKNFALIEELSISFDKGFNVLTGETGAGKSILIDAISYVLGGKFNRDLIRTGENKTYVEAIFSIENESTERILKDQGIDFEDILIIGRETFQYGKSIAKVNAKSVLLANLKEITSTLLDIHGQHENQNLLSCENHINYLDYFSEKELYSIMEKYKSEYLNLLNIENKIKELSGGDESEREKLMDFLKYQIKEIGESNLKEGEEEELDNKFLELSNAEKISKVLNNSYGILYGGLEEESSAFDSLGYVIREMESINSIDKITSICQSLKDAYYIIEESIRNIGDIKDNIYYDENELDRINSRLFQISTLKKKYGTTIKEIIEYKDKIEKQYEDMINSEEIIEKLNNDRKKVLNNLKEIAMQMHNVRVKYAEELEVRVKEELSYVGLSKTRFKINVDLVSSFFKSGCDKVEFYVSTNPGEPLKPLDKVVSGGELSRIMLALKTVFVDKDKIPSVIFDEIDTGISGVVAQSVGEKMYSISHGRQVFCITHLSQIACMSDNHYYIHKEVLQDKTYTKVTKLSKEDKEIEIGKMIGGSNLTDITLQNAKEIIKIADNKKEKILKNS
The following text describes a protein:
Function:
Protein that helps load RecA onto ssDNA during transformation. Binds cooperatively to circular ssDNA, is able to bridge different segments of DNA. Favors the loading of RecA onto SsbA- or SsbB-coated ssDNA and formation of RecA-DNA filaments. RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP.
Subcellular Localization:
Cytoplasm. Note=Localizes mostly to the cell poles during the development of competence. During competence a number of proteins (at least CoiA, ComFA, ComGA, DprA, RecA and SsbB) are thought to colocalize at the cell pole, in a disruption of ssbB DprA no longer accumulates.
Sequence:
MDQAAVCLTICRINQLLSPSLLLKWWKADPSMSLTSPVLQTVTRDQIKAAALKNEIEQFYPKLPRVLAAYREQGINTIPISSKQYPFWLKSIYDPPAVLFAKGDMTLLSKGRKIGIVGTRNPTAYGKQVVNHLTKEICRKGWVIVSGLASGIDGMSHAASIKAKGRTIGVIAGGFQHIYPRENLQLADHMAKHHILLSEHPPETKPQKWHFPMRNRIISGLSEGVIVVQGKEKSGSLITAYQALEQGREVFAVPGSLFDPYAGGPIKLIQQGAKAIWSAEDIFEELPERNVQYTEPF
The following text describes a protein:
Function:
Converts carnitine to trimethylamine and malic semialdehyde. Can also use gamma-butyrobetaine, choline and betaine as substrates.
Sequence:
MSDYQMFEVQVSQVEPLTEQVKRFTLVATDGKPLPAFTGGSHVIVQMSDGDNQYSNAYSLLSSPHDTSCYQIAVRLEENSRGGSRFLHQQVKVGDRLTISTPNNLFALIPSARKHLFIAGGIGITPFLSHMAELQHSDVDWQLHYCSRNPESCAFRDELVQHPQAEKVHLHHSSTGTRLELARLLADIEPGTHVYTCGPEALIEAVRSEAARLDIAADTLHFEQFAIEDKTGDAFTLVLARSGKEFVVPEEMTILQVIENNKAAKVECLCREGVCGTCETAILEGEADHRDQYFSDEERASQQSMLICCSRAKGKRLVLDL
The following text describes a protein:
Function:
Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.
Sequence:
MEISSVPLYRPHSPGLHQRGGNTFTVVPKRKPVASGLQGLTEAGGRPQREEEEEDEESKGRSKAVENADGPQVGPSHKKRYPTVNEIEVIGGYLSLERSCISKTGSRRKKAAARCDPVRPLQDAELRAALEVLRCYGLHAAVEEWFLEVLQTDLQAHIAPEFWNCVGQYENTAEEQQCSALLLDAFCLLKCRLEPYLSSMELLEGWTEAGLLLGTGAQTLREKVYTMFKAILFFSTTKPFQEMIQQFYSRTFRIYMRQWKKGEEGMNECESSMSEAEQESDTEEGGGESAVCAGCGSRREQCWCPTAMERFRQLNHILRRLNLLERVSADAVTTILHRMIKERMERRCRGEYEHSFLNEFQEWIEKVLGWLSRVFLQDGPLARPSAEASSTLRRWRCHVQRFFYRIYASMLIEELFSIIRDFPESKPAVEDLKFCLERTNLRQQLLSSLKSALEIRLLHPGVNTSDIITLYISAIKALRELDPSMVILEVACEPIRKYLRTREDTVRQIVAGLTGDAEGSGDLANELSKADPVTLENGQESDDDISEPGDWVPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRTLLADRLLHQFNYSAEREIRNVELLKLRFGEAQMHYCEVMLKDMADSRRINANIRDEEEKLPEEERPPFSLVAVILSSEFWPPLKEEKLELPEQVKEAMEAYSKKYEKLKAMRTLNWKYHLGLVSLDVELADRTLSLSVSPVHAAIILHFQTKSTWTLAELSEVLKVPVTSLKRKMTLWLQQGVLREEPPGTFTVIEEEQKDQGEKVVLIDSDEEGDSAMASQADQKEEELQLFWTYIQAMLTNLESLSLERIHSMLKMFVMTGPVVTEIDIQELQGFLQKKVRDQQLIYSGGVYRLPKNCN
The following text describes a protein:
Function:
Part of the ABC transporter FtsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KinC, the RapA phosphatase and the Spo0A sporulation protein.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is localization dependent on FtsZ.
Sequence:
MIEMKEVYKAYPNGVKALNGISVTIHPGEFVYVVGPSGAGKSTFIKMIYREEKPTKGQILINHKDLATIKEKEIPFVRRKIGVVFQDFKLLPKLTVFENVAFALEVIGEQPSVIKKRVLEVLDLVQLKHKARQFPDQLSGGEQQRVSIARSIVNNPDVVIADEPTGNLDPDTSWEVMKTLEEINNRGTTVVMATHNKEIVNTMKKRVIAIEDGIIVRDESRGEYGSYD
The following text describes a protein:
Function:
The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
Sequence:
MSLRIVVTVKYVPDATGDRHFADDLTVDRDDVDGLLSELDEYAVEQALQISENSDDDVEVTVLTVGPEDAKDALRKALSMGADKAIHVEDDDLHGTDAIGTSLVLAKAVEKAGYDLVVSGMASTDGTMGVVPALLAERLGVPQVTLLSEVSVEGGVVKGRRDGDSATEQLEASLPAVVSVTDQSGEARYPSFKGIMAAKKKPVQSWDLSDLDIDEDEVGLENAYTVVESATERPARTAGTIVKDEGEGGKQLAEFLAGQKFI
The following text describes a protein:
Function:
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
Subcellular Localization:
Cytoplasm.
Sequence:
MGIKSIVINEQQIEEGCQKAVNWCNAKFNNKKVIVLGILKGCIPFLGKVISKFSFDLQLDFMAVASYHGSHVQKQPPKIVLDMSHDPKDKDILLIEDIVDSGRSIKLVIDLLKTRHAKSITLISLIEKIKPKAFDINIDFSCFKVKDNFLVGFGLDYDGFYRNLPYVGVFEPDNP
The following text describes a protein:
Function:
Flavohemoprotein involved in nitric oxide (NO) detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the protozoan parasite from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress. May also be involved in O(2) detoxification.
Sequence:
MTLSEDTLRAVEATAGLIAAQGIEFTRAFYERMLTKNEELKNIFNLAHQRTLRQPKALLDSLVAYALNIRRINELYELKGKGLPVPPEHWAELQGFFSAAERVANKHTSFGIQPAQYQIVGAHLLATIEDRITKDKDILAEWAKAYQFLADLFIKREEEIYAATEGCKGGWRQTRTFRVEEKTRVNEIICKFRLVPAEEGAGVVEHRPGQYLAIFVRSPEHFQHQQIRQYSIISAPNSAYYEIAVHRDEKGTVSRYLHDYVSTGDLLEVAPPYGDFFLRYLEADEQAPADTQASQEFQMLQSGAINFAAEKTMPIVLISGGIGQTPLLSMLRFLAQKEGKETARPIFWIHAAHNSRVRAFKEEVDAIRETALPSLRVVTFLSEVRATDREGEDYDFAGRINLDRISELTKLEADNANPHYFFVGPTGFMTAVEEQLKTKSVPNSRIHFEMFGPFKASH
The following text describes a protein:
Function:
Functions as the terminal component of an NADH peroxidase (NADH:H(2)O(2) oxidoreductase) when using NADH:rubredoxin oxidoreductase (NROR) and rubredoxin (Rd) as electron transport intermediaries from NADH to revRbr 1. Plays an important role in the oxidative stress defense system in C.acetobutylicum, an obligate anaerobic bacterium. Also exhibits NADH oxidase (NADH:O(2) oxidoreductase) activity in vitro, which is 100-fold lesser than that of FprA1/2 using the same electron transfer components. Therefore, its predominant function is most likely as a scavenger of its preferred substrate, H(2)O(2).
Miscellaneous:
MISCELLANEOUS: This protein has been named 'reverse' rubrerythrin (revRbr) because the order of the two functional domains is reversed compared to 'classical' rubrerythrins: the rubredoxin-like FeS4 domain is located at the N-terminus and the ferritin-like diiron domain at the C-terminus.
Sequence:
MKKFKCVVCGYIYTGEDAPEKCPVCGAGKDKFVEVKDEGEGWADEHKIGVAKGVDKEVLEGLRANFTGECTEVGMYLAMARQADREGYPEVAEAYKRIAFEEAEHASKFAELLGEVVVADTKTNLQMRVDAEKGACEGKKELATLAKKLNYDAIHDTVHEMCKDEARHGSAFRGLLNRYFK
The following text describes a protein:
Function:
Chemotactic for neutrophils. Involved in lung-specific neutrophil trafficking during normal and inflammatory conditions.
Subcellular Localization:
Secreted.
Sequence:
MAAQGWSMLLLAVLNLGIFVRPCDTQELRCLCIQEHSEFIPLKLIKNIMVIFETIYCNRKEVIAVPKNGSMICLDPDAPWVKATVGPITNRFLPEDLKQKEFPPAMKLLYSVEHEKPLYLSFGRPENKRIFPFPIRETSRHFADLAHNSDRNFLRDSSEVSLTGSDA
The following text describes a protein:
Function:
Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation.
Subcellular Localization:
Nucleus.
Sequence:
MASTSSGSSVDRVELRRQAQLQRAGMKVSTETPAVSKPLFDAPVKIDPPPDDHVYRKTQETLGQFNLIRHSMLSSHNQYLLGIPKGPQTPILNKTADSVWASKFPANGQLPPQKPAGAHRPKPSGRSSSAERSRGSKSPAEKRPHGRSSANHKSSSHGAKGADKPEEKKRQEEPRDIKESRPRPSEAGHERRKSSGGGKRRSVSPHPPRKDGQVTSGQVTSGQSHSSKAPGEPNSKSAHSRPEKSPPVQPDSSSSASSSIKMEASSTKDDAFQMPAPLSTAPGSHRPSHSGGKTSDRPEERPNGLLATPGHGGKKEGVEKELSREDVKRKLTLTMPDTSEEARLNSSGGLKSAGTEKVEIILKEMTEVGPPLTGIHTPIKTDVSKFPFPANQDVPSAQLSRTKRKTTAESSGGGKTKPMGPSSELKKYFLDMSDSEDDDDQARQTKTSGRNAQKMRSPARRTPMLSSGSSSSSSGSEDSSDSDSEGSSSSDESVQDAPPPASPPKQESDTTNWGLASFVNPVKRDSPGNSFPLLVSAGGGGTPAANTANSVALPMGLFGGDEGPLSSAGFMTSSDSHGFDVNDILQPLDSSKELDPDHKDNYSATKINGLRMKISKKGQGGPEPTGCSSNSTSSSNKEVSKKSSVGKSPSTASRNSSKTATNRTPRKGADKKPAERPASASNAKAESSEKTKANSSKAGQTTPSNKTNWAEPSPKTDKTTKTVQGKKSSDKKGKRTPQTSSKVKSKEFIDSDSESDLEVDVVNISPEKGGASAKASPSPRAKLNSSSKPKARDSGKKAAASSSGGGSQEKALSVDVLSSDNSLLSPLNEPLLSPIEGDLASTVPKITYGNNGIPKSLIVSIDLSLLDRIPARKDSSRQGDSKKSSSSSESKPRSKVQKRKRDNSQSQADAAGASTAEEVQTKRPKKEKEATSDSKATPTRSLPTPTRTLPTPATSLSTPTRNLPTPTRTPSQATPTRTTPTRTPPGGRQDSEKGRGSARRSSVSSTSSRLSEESAKTDRSAKRRKVERQTSQESSKKKEKDWDAPPAVVPEHSQNGVATEPVAKATNGHAAGSQWGELASGQQGGKAWERHDPRGDIPYFTSSKTDTEERPLSADHYLTEAKNLKHLADGLADKNQKTLTYVDAVLYFIQCGNAMESDPHLSESKSPSTMYLETVDLIKFILRFNSHHMHNQSQDQTTSDKKLAVLCLRCQSLLYMKLFKLKKDYAMKYSKALTDHFKNPPKNTQVPSPYQHNWNGARGTGTPSPMSPTPSPAGSVTSVGSQGSNNGDLTLNTPTQNKLSNGTSGSSVTIPQRIHSLMQEHLKITNHLLHSQDLWEQANTLAQENPEFFRRLDQRLGALTLHSTLIELVRYVRQGLQWLKES
The following text describes a protein:
Function:
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSQTIKTGAREVAASLAVTMALLVSCFLYLRNDIMVSQQPCEMTYMYAQYEPVDMPAELLISAGTRARSAGASSRSSNASGWHRGDSVAQQEVPAWGRDMTAAAARVAEVAAELAGDRHRLWRYTGESSHGPGTDPRAPPALPILFIPGNGGAHEMGRSLASETARRLGRLGPGARLAGAGADWYLMDLEGEWSAFDGDTLERQVSFMLAAMRHLARTYNITTACSSDSSSSSSSSSSSSSSGSSCRPRTGATAHPGMVVVGHSMGGVVAAEAIARAAAEPDLGPSLVALLLTLGSPHARPAVPGHPSLLRFYQRAAAGAAGAGAGAGASGAAGVGARGRPVVPVVSIGGGAADVQVAAALTDPSSLAPAGLSRGLSLPAASPGAWCPAAHNSLVWCNQLVAALGQALVDMAQDAFPSLDAARKPVPTAATAAAANKPPRPGPSGPGGELATAELDAALREGHRPDSADGGSGSGSSSSYSSDGSSSSSSGSSSPPPAVCGPEGLGRWSWALRRVEARLGHPAQPYLATALMAATAAEARRGPDATAATATASEAAAQAEATSELLRRAKPALAPAAAGGAACGGANLAWYLQYQSPAAQPRQGRTALRLLPYDLVGAPGTGRTFSWRLGRWQGAGDASRLPRGWSGWLSGAQPCTAFRVWLSVVVEQPASPATATAAAATAGSSSGSSSSSSGGSGGEGREALEELEAEVRRAAAAPARTLRHDVEVTALAAPLPAVVPEGRWHVRNRSAWGEIQGGRDYQSRAAWLLLLPPALVEPLLQLQPGAPPLRPAGALGGGSSSKPTVTLTLTLWLAAAPSYEPAFRVVAAPLLPPHEPADRPLPLRPSPGSPEVVLQRQPRASSLSAAATAAKKKGAGAPPPLLLPLQLPHLTPPLLLPIPAGGAAASSSSRGSSAGSSVSSSGEAGSSRTYTLEDGSAIRVERALAGEAAAASPLRAALTAAAVRWLGLWRYAALRITALDSRGRPLLQPPNAGSAAKGGGRSQRRRPSVAGKGGDEGEEEEAEEEEEGGAGAGVGSCLYPVVMLVGGSSSGGSGGGSSASDWQAATLLQVSANHTYHSLEPCAAAGPAGCAAAAALLDPACAHRVEVVPFLAARLQQLLGSQLGRLWLGAQLAALAAAGGLAAAAAARRRAAAAAAADAAAAMVDGGDGGVSAGAGEEGGGGGGGRWRRRGGGVGFGGWPLLPLDALDVLAEVMWRRPVAAAAVLLATAATTALMAHASSAWAAAAAAAAAAAEAGAEAAAAAGGDVAAAVEAGLAAVAKSCGALAAAWPLVRRGAVALGLCPLPHLAGCGWGASVSEWPGGFSAWLAAATNATASTTAAAATATAAAPVVLAAPPLDGETLAALDWALLAAAAALTAWLLAAPLQLAAAAATAAEAALGAAWWLAAVLPYRIVTAPMAAARRRRQAGSSGSGSTGPAAPGGGGGSGDVVLGPAARAGLAAAARCSLRAAALAAAVVLAGHAAAAPGAVLLAAVLSLAQALSSPAAVLPSPPPLPKPPRRPAAVAAGKRAGATGAGAAAAAAAAAGSAGPPPDGDNAAAEVAAGEDVPQEWWRDAWWDEPWREDMNEPCSRDGDGNMAVGGVAMAGGQRRRRLTTATAAGRRRRAALQAQHAAHEAAVAVRHCRLAWLLYYAAYGACAAPAVVAVLRRLVLRWAAVGRLAGAVGEAALAAVSAASGGQVLGVAALAAGGLRDAVVGALAAACGGAAAWVGDLAAGGGVGQAGYVLAALHCAALAVAAAAEAAKGHAAAAAEASGSDGSAASGRSGGAGKAGGGGGAVAGGVQASSSGAAVAQGRGSGRWAVSAAIRGLAVVAGCVVLAMAWWLGAAEAAHLVAAGVALAQLVLVLQAAS
The following text describes a protein:
Function:
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQLLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWMVTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVLLSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRISIQ
The following text describes a protein:
Function:
Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MLSPFLAYLLSVVLLCRIARSQYSSDQCSWRGSGLTHEGHTRGVEQVYLRCAQGFLEWLYPTGAIIVNLRPNTLSPAASLLSVCIKPSKESSGTHIYLDRLGKLRLLLSEGDQAEGKVHCFNIQDGALFIEAVPQRDISRKITAFQYELVNHRPGADPQSLSAPCQPCTDAEVLLAVCTSDFVARGRILGVSEEDEQTSVTVSLSHLYRQKTQVFVSGGGRAKRWTGFVKMSRQCGVKPGDGEFLFTGTVRFGEAWLSCAPRYKDFLRVYQDARQQGTNPCHLETD
The following text describes a protein:
Function:
Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B. Also functions as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3. Binds to the rhodopsin promoter in a sequence-specific manner.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MALPPSPLAMEYVNDFDLMKFEVKREPSEGQSGPPTASLGSTPYSSVPPSPTFSEPGTVGATEGPRPGLEELYWLATLQQQLGAGEALGLSPEEAAELLQCQGPVPVEGPHAYYPGSPEETGAQHAQLAERFSDAALVSMSVRELNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLAPSGGAGGHAHFFLR
The following text describes a protein:
Function:
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
Subcellular Localization:
Cytoplasm.
Sequence:
MEYANGNCNGTTSTHDDDQVFCIKPQQQQQQQEHEDPLNWNMSADAVKGSHLDEVKRMVDEFRSPVVRLGGETLTVAXXXXXXXXXXLSEAARAGVKASSDWVIEGMRNGTDSYGVTTGFGATSHRRTKQGAALQKELIRFLNAGIFGNGAESCHTLPHSATRAAMVVRINTLLQGYSGIRFDILEAISKLLNNNITPCLPLRGTITASGDLVPLSYIAGLLTGRANSKATGPNGEVLDAVTAFQRAGIDTGFFELQPKEGLALVNGTAVGSGLASMVLFEANILAILSEVLSAVFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSSYVKEAKKIHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRSSTKMIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVSMDNTRLALASIGKLMFAQFSELVNDYYNNGLPSNLTGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTEEALDILKLMSSTYLVALCQAIDLRHLEENLKATVKSAVSLAAKKVLITGQNGELHQSRFCEKDLLTVVDREYVFAYADDPCSATYPLMQKLRQVLVDHALKTSNTEIFQKISAFEEELKLVLPKEIESVRCALENGKAPIGNRIQECRSYPLYKFVREELGAKYLTGEKVLSPGEEFDKVFTAINEGKLIDPLLNCLKEWNGAPLPLC
The following text describes a protein:
Function:
Involved in telomere length regulation.
Subcellular Localization:
Mitochondrion.
Sequence:
MLRVVAKAQYPAAVRCFSTSHAAFAKVSFESSEDFLKKIGRDTVKLAEKFETWDELKNSTSSDLKEKGIEARDRRYIMTQLYRYKNGEKIREIPRGKKTWGGERKRNLVQALFKAGQN
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MASTFSQSVFARSLYEDSAENKVDSSKNTEANFPITLPKVLPTDPKASSLHKPQEQQPNIIPSKEEDKKPVINSMKLPSIPAPGTDNINESHIPRGYWKHPAVDKIAKRLHDQAPSDRTWSRMVSNLFAFISIQFLNRYLPNTTAVKVVSWILQALLLFNLLESVWQFVRPQPTFDDLQLTPLQRKLMGLPEGGSTSGKHLTPPRYRPNFSPSRKAENVKSPVRSTTWA
The following text describes a protein:
Function:
Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Cell junction, adherens junction. Note=In epithelial cells localizes to the apical junction complex composed of tight and adherens junctions. In airway epithelial cells localized to basolateral membrane but not to apical surface.
Domain:
The Ig-like C2-type 1 domain mediates homodimerization and interaction with JAML; The PDZ-binding motif mediates interaction with MPDZ and MAGI1.
Sequence:
MELLLRFLLLCGVADFTRGLSITTPEQMIEKAKGETAYLPCKFTLGPEDQGPLDIEWLLSPADNQKVDQVIILYSGDKIYDDYYQDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVGNKKIQLTVLVKPSGIRCYVDGSEEIGNDFKLKCEPKEGSLPLRYEWQKLSDSQKLPTSWLPEMTSPVISVKNASAEYSGTYTCTVRNRVGSDQCLLRLDVVPPSNRAGTIAGAVIGTLLALVLIALIVFCCHKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDLERAPQSPTLPPAKVAAPNLSRMGAVPVMIPAQSKDGSIV
The following text describes a protein:
Function:
Involved in resistance to oxidative stress (e.g. hydrogen peroxide H(2)O(2)), high light and heavy metals (e.g. cadmium ions Cd(2+)). Influences responses to reactive oxygen species (ROS) production. Together with SIA1, regulates iron distribution within the chloroplast and mediates the oxidative stress response. Together with ABC1K7, influences chloroplast lipid synthesis/accumulation and modulates chloroplast membrane composition in response to stress.
Subcellular Localization:
Plastid, chloroplast envelope. Plastid, chloroplast membrane; Single-pass membrane protein.
Sequence:
MATSSSSSSSLLLPNINFNSRQSPTITRSVSIAGIFLPRNRLSYNHNLRIRTRLIRASKDDNVAVEDRDNAVKINGDYNGSARLNGNGSARKSVNGDFNGSARLNGNGSLVKYVNGSVTVETEEVTKKRKEEVRKKRVEDIGQEDAWFKNNTQQKQVEVSVTPGGRWNRFKTYSTIQRTLEIWGFVVQFIFRTWLSNKKFSYKGGMTEEKKVLRRKVLAKWLKENILRLGPTFIKIGQQFSTRVDILPQEYVDQLSELQDQVPPFPSATALSIVEEELGGSVEDIFDRFDYEPIAAASLGQVHRARLKGQEVVLKVQRPGLKDLFDIDLKNLRVIAEYLQKVDPKSDGAKRDWVAIYDECASVLYQEIDYTKEAANSELFANNFKDLEYVKVPSIYWEYTTPQVLTMEYVPGIKINKIQALDQLGVDRKRLGRYAVESYLEQILSHGFFHADPHPGNIAVDDVNGGRLIFYDFGMMGSISPNIREGLLEAFYGVYEKDPDKVLQAMVQMGVLVPTGDLTAVRRTALFFLNSFEERLAAQRKEKEEIAAAEELGFKKPLSKEEKQEKKKQRLAAIGEDLLAIAADQPFRFPATFTFVVRAFSVLDGIGKGLDPRFDITEIAKPYALELLRFREAGVEVVVKDLRKRWDRQSQAFYNLFRQADRVEKLAVVIERLEQGDLKLRVRALESERAFQRVAAVQKTVGSAVAAGSLVNLATILYLNSIKTPATIAYTVCAFFSLQVLIGIIKVKKFDQREKLITGTA
The following text describes a protein:
Function:
Histone methyltransferase that methylates 'Lys-36' (H3K36me) of histone H3 to produce H3K36me3. Promotes early stages of cellular dedifferentiation through H3K36me3-dependent, and to a lesser degree H3K4me3-dependent, activation of Lateral organ Boundaries-Domain (LBD) (e.g. LBD16 and LBD29) genes. Positive regulator of root organogenesis including lateral root formation as well as adventitious root formation from wounded leaf tissues. Recruited by JMJ30/ARF (e.g. ARF7 and ARF19) complexes to promote the deposition of H3K36me3 and, to a lower extent, H3K4me3 at LBD genes promoters, thus ensuring their stable activation during callus formation on callus-inducing medium (CIM).
Subcellular Localization:
Nucleus.
Sequence:
MDSVYKTDENFAADVAALLAPLPTPQLQEYFNKLITSRRCNGIEVKNNGTIGKGVYANSEFDEDELILKDEILVGIQHSSNKVDCLVCSFCFRFIGSIEKQIGRKLYFKNLGVSGCCDDDSSEEDECVKYNGNEEQCGGSSSSHNTLPEGVVSSLMNGEMALPHTDKFPLPSPLSCPGGCQEAFYCSESCAAADWESSHSLLCTGERSESISREALGEFIKHANDTNDIFLLAAKAIAFTILRYRKLKAEHVDKKAKQSEPKQSLLLEAWKPVSIGYKRRWWDCIALPDDVDPTDEGAFRMQIKNLACTSLELLKIAIFDKECEALFSLEIYGNIIGMFELNNLDLVVASPVEDYFLYIDDLPDAEKEETEEITRPFLDALGDEYSDCCQGTAFFPLQSCMNHSCCPNAKAFKREEDRDGQAVIIALRRISKNEEVTISYIDEELPYKERQALLADYGFSCKCSKCLEDSSSI
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus envelope.
Sequence:
MNRARLQLASLWLLLAVTRLQAVAASALGTTERDMDVKALIRVRAAQGNLTLEGLFARVAEISPAEGKLLQFHPLSLCNTSEDDQTKPGFISIVKLETPDSDTQPCLSLANKARLAGERGAHAILFDISNDRGALQQLQQPAGINQPVVLIWGPDAEKLMEVVNKNKEALVKIEVQEQPKWLHHDVWILLTLSATVLFIILCAVARLRCRQPPPQDSIQQQTLVAISCLATRRYQQRVLKEQRASGGRVDTASTSSSVPVCAICLEEFTDGQELRILPCCHEYHLICVDPWLRQNHTCPLCMYDILDSGTSAQPPAHRTASQTPLWGRYPGSARLMSHLPPNGLPMVFPTPDNSIFLSRAPYYLDQTHHWQTPEQMPMQIRTHRRGAECPRESGYLPDDPGSDSSSGPCHGSSSENCTDISLHCLHGTSSSSVHSSQSNQEDSSPPALASYLLPQSELPALNPLLSPQASYANHVHFHQHRHHHYRRNSHRSKRRTKVSRADPGYYREQRHITGTNGESRSLMIRREPRPSCSRTCFDPRTNREHIRHHQSMPQAASVVQGSSEPDVDTSLRPSRTDPPSRTYRKKKSSAPSHLPLLHSPRHFHPANSVQVCESAQPRWAEEVRLLHSRVNSHRENTAMMHLYHPPHHNQGAREEMEAVCEHAV