lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Acts a component of the ESCRT-III complex, which appears to be critical for late steps in MVB sorting, such as membrane invagination and final cargo sorting and recruitment of late-acting components of the sorting machinery. The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complex assemblies (By similarity).
Subcellular Localization:
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Sequence:
MGLTSWLFGGGKSPQEQLRAHQRSLGRAERELDRERTKLDQRERALIQEIKGSAKAGNTGAARIQARDLMRLRNSRKKMMNAKTQLQAISLRLQTMRTSEQMMQSMRGATRLLTGMNKSMNIPAMARITQQFERENEIMEQRQEMIDENMDDALEEDDEEEADELVNKVLDEIGVDLSQGLPDAATQIGTVPELKTEDNLQARLDELAKR
The following text describes a protein:
Function:
Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
Subcellular Localization:
Secreted.
Sequence:
MKIAITITVVMLSICCSSASSDICPGFLQVLEALLMESESGYVASLKPFNPGSDLQNAGTQLKRLVDTLPQETRINIMKLTEKILTSPLCKQDLRF
The following text describes a protein:
Function:
May be involved in recombinational repair of damaged DNA.
Sequence:
MLVDIAIENLGVIPAASAEFSSGLTVLTGETGAGKTMVVTGLRLLSGGRADASRVRTGSPQAVVEGRFVTQGVPCDIVERATGIVSNAGGAADENGEFLAVRSVGANGRSKAHLGGRSVPAATLSEFSDELLTIHGQNDQLRLLSPERQLEALDRFDPELAQLRKNYNAKYLTWKSLDKDLQKRLSSRRELAQEVDRLQFAINEIEEVSPQPGEDAELVEQIRRLQDVDTLREQAATALAAIDGAGSLSDAMGGSGGFDESQESASDQLGQAESALAGSDDSKLKDIAVQLAEITSQLSQVSMELGGFLSDLPADPQALDDMLTRQQQLKLLTRKYAADIDGVIEWQRKAQIRLDSIDISSEALDKLKEDAKKAQASMMRAAKKLSAVRAKAATKLGTTVTEELQGLAMQKARFEVALTSIEACASGIDQVEFQLAANAFAQPRPLASSASGGELSRVMLALEVILAAGTTGTTLVFDEVDAGVGGRAAVEIGRRLARLATKNQVIVVTHLPQVAAYADTHLHVAKNVGEASVTSGVESLTFDRRVEELSRMLAGLDDTATGRAHATELLERAQREKEDINEERVEPLLAASA
The following text describes a protein:
Function:
Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MGSPGMVLGLLVQIWALQEASSLSVQQGPNLLQVRQGSQATLVCQVDQATAWERLRVKWTKDGAILCQPYITNGSLSLGVCGPQGRLSWQAPSHLTLQLDPVSLNHSGAYVCWAAVEIPELEEAEGNITRLFVDPDDPTQNRNRIASFPGFLFVLLGVGSMGVAAIVWGAWFWGRRSCQQRDSGNSPGNAFYSNVLYRPRGAPKKSEDCSGEGKDQRGQSIYSTSFPQPAPRQPHLASRPCPSPRPCPSPRPGHPVSMVRVSPRPSPTQQPRPKGFPKVGEE
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U20 in cytoplasmic tRNAs. Also able to mediate dihydrouridylation of some mRNAs, thereby affecting their translation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGLLNYSNKVCLAPMVRIGELPMRLLALRYGANLVWGPEIVDKALLSGTPVERVVNDRINCIDFVKPPSNKVLFRVHPLEANRLIFQLGSASPELAVEAAKLVANDVAGIDLNCGCPKHFSVHAGMGAGLLKNQDRLVSILDALVNEIGKPYKISISCKIRLLETKEDTLKLVERICDTGVRAITVHCRTTPMRNTEPADRSYLSEIVGVCRNKDVSILVNGDVLSYNDGLDVIEKYGVDGVLIARAAERNVSCFRIEGPLSSFKVAEEFLKMALEVDNNFGNTKYCLNQIMQGSFRKNVRQLAQTAKTYEDLKKAFEIEYKHSDASSVCPTLEKEKSLVISFVDLPSFLESLLASNILKQLSRLHFTKIFAVSEEEDICKQLDDIHEKFLCHGIALSLISADNLASAIASAHLVICMEKDESIMNEAVCDQKITIRLPINSNTNEAVVECENKSMQSKHALDIIQERIKDLEEKAQVV
The following text describes a protein:
Function:
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MPGMLAAQFTALSLSQSPSPQSSLRLAIRPSLAARARFVAPRTAASAAAVSAKPAAVSSPLIEDRTVVRIGLPSKGRMAEQTLSLLKSCQLSVRQLNPRQYTADIPLIPNLEVWFQRPKDIVRKLQSGDLDLGVVGFDIVSEYGNGNEDLVVVHDALEFGHCRLSLAVPKEGIFENIHTMEDLLKMTEWTEERPLRVVTGFGYLGNKFLREKGFKHVRFLSADGALESYPPMGMADAIVDLVSSGTTLRENNLKEIDGGVVLESQATLVASRKSLHKRKGVLEVTHELLERLEAHLRATAELMVTANMRGNSAEEVAERVLSQTSIWGLQGPTVSPVYRRRDGKVDVEYYAINVVVPQKLLYKSIQQLRSIGGSGVLVTKLTYIFDEETPRWRNLLSELGL
The following text describes a protein:
Function:
Receptor for basic fibroblast growth factor.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MTINGVTASQCAAQCLTGTGTVPFGFCRSFDYDNGRQRCVLSREDKDTVSQSLDPNPAVRYHQLNDPFSFFTKTADAGLYGFNTHVLSNHNATMCALRCLLGTDTVSTVNCRSFEFDKNYNKCILSVEDGITEPSEVGAAGSNTRFDFYQRNGQCDSSPCQNSGTCRNGFDSPESYTCTCSPGWGGDNCETDIDECTLGIDNCHDQATCSNTGGSFSCTCDTGYTGDGVTCTDTNECTAGTDNCHDQATCTNSVGSFSCACDTGYTGDGVTCRDIDECTLGTDNCHDQLAACANTAGSFSCTCNTGFAGDGVTCTDTNECTLGTDNCDTQATCTNSIGSYTCTCDAGYTGDGVTCTDLNECTLGTDNCRILATCSNTAGSFSCSCNTGYTGDGVICTDINECADNTNNCHRNADCTNTAGSFTCACGDGYYGSGTSCIACGQCTGGVACNTVTGVCSSCQPPWTGQLCQQIPAEVTTDPQDVTQSLNFAAVFTCGGRGEPIPTVTWQQDGSPVTNGVSTTTNIAQYTFSSTLSFNRVQRADNGQYTCTAATNGLNTDISQPATLTVLEPPEQVTVTVMPTSSTLQVTVTVGFTGNLPITAIQVRYQRTDESTWSSWHPAVVTGTQATIDITGLTPATDYTGEVRAQNSEGWNQAVQFTWRTRDAPPGPPSNLQAPSVSHHTIDLTWQEPAVTNGVITNYNIQYGSTTECSDAELTYWWNTTDSSTSKTFPGLIPYTTYSFRVRAFSIAGPGDYTGCVTAKTTEYTPTEPTSVELADVNPCNCENDNQPRRIMLQARWRRPRHVYGELRGYNLKLKHQDMVIYDYNITDGLENDVLTYEMTENEIAVLQPAQEYYIMVFAYNDVYVGEVSTSRESQTSDGCPTAPLISKMTQEGKCAVNWTEPSRDKGNITGYSVVISATKLGTDTPLEPVSTSEVTNRTWAASIDDLPAFSLVHVTVRAKTCAQGESSEEIACTVERIESPNTIPNVTVEDSSVTSSSFSIMLPNISQRNGPISCYQVIIVPMRKDETLDELTVRVGQPQKVLTSSAPTDGRTEPYIALAFSGSSYKEERVTIGTGEPCTEPCCRVGSEEGAPEPGNRPLTPGSTYTATVRAYVGISGQEDVREKAVSRAQTSSLFMEPIITVLEEALPLVAIIVAVVAAVIASFAAGAGFMFYRRNYINIKKETTNGRTDVPLSDITCKEDSEVEGVHNEALSISEADSKSYRRLSEIRTVDDVTKYLKENKFGEYAKAFRDHEVDGDALKYLDDAILKDLIPKAGPRAKFKGILAEFKQEKPSQVSELPTLNFWEIPRTGLKLGRRLGSGQFGEVRLGELRNRGLTSTVAVKTLRDSASDSDKKDLLGELEILVTVGRHDNIISLVGACTKDGPLMIVVEYAPHGCLKDWLKTNSAENNAESAYQNQPVYASQLPMEQLIQFGVDVANGMSHLAALQCVHRDLAARNILLGENLVAKVSDFGLSRDIYEDSEYVKSTQSKLPLRWMAYESLFYNVYTTQSDVWSFGVLLWEIMAMGNLPYEGMKGKRMMDMIKDGGRLQKPSSCPEELYTLMTRCWETLPEDRPTFPELKSSLIRIMQGFKTYASLLK
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase involved in the regulation of root growth. Acts as a positive regulator of root gravitropism. Possesses E3 protein ligase activity in vitro.
Sequence:
MGTGWRRAFCTTAPRNSDAAAPDLDKQRTGYNLTPSPSPRSCVKLAFLSGGSNPSTPRSTSSPSLRCRTADAQTPTAEQTSTPRSATKSPRLSLAAISNPSSPRSPLKLSLFRNSFKFRSTCGICLNSVKTGQGTAKYTAECSHAFHFPCIADYVRKQGKLVCPVCNSIWKDASLLVPHKNATESPLDDSVSVIQEKRVVVTSSPRAKPRPKQSDYSRFYDDDEPLLSPRFVTIPEADENCGGEEEDDVPQFKGFVVDPNPSFAVKTNEIPVNGRDFGNVQVSLLPEAAVVSVGCGYETRAVALRVKAPPPLTARGGVGRRLLDPSQRAPVDLVVVVDVGGTMNGAKLQMVKRAMRLVISSLGSADRLSIVAVVMTVPKRLLPLKRMTEHGKRSAGAVVDGLLCGQGSNTSEALKKASRVLEDRRERNPVASIVLLTDGQGQLSKVHTNQRSTITNVGSTRFAHIEIPVTEHGFGESGGCSNAPAEEAFAKCIGGLLSVVVQDLRIQIRVGSGSGPCEISAIYLCNGRPTLVSSGSGSVRLGDLYAGEERELLVELRVPSTATRAYQILSVRGLFKDPSTQEVVYGRDQSLRVPQAVRSSSSPRIERLRSLFIATRAVAESRRLVEYGECTSAYHLLTSARALLGQSGTVEAAEYIKVVEAELVEVQWRGQQLMEYQSQHQQQHNQRRRGSERETTTTMTLMDENGEPLTPASAWRAAEKLAKLAMMKKSDLHGFENARF
The following text describes a protein:
Function:
Acts as a virulence determinant.
Subcellular Localization:
Secreted.
Sequence:
MKSVKIMGTMPPSISLAKAHERISQHWQNPVGELNIGGKRYRIIDNQVLRLNPHSGFSLFREGVGKIFSGKMFNFSIARNLTDTLHAAQKTTSQELRSDIPNALSNLFGAKPQTELPLGWKGEPLSGAPDLEGMRVAETDKFAEGESHISIIETKDKQRLVAKIERSIAEGHLFAELEAYKHIYKTAGKHPNLANVHGMAVVPYGNRKEEALLMDEVDGWRCSDTLRTLADSWKQGKINSEAYWGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEGFEKNPEIKPNQGLRFITSEPAHVMDENGYPIHRPGIAGVETAYTRFITDILGVSADSRPDSNEARLHEFLSDGTIDEESAKQILKDTLTGEMSPLSTDVRRITPKKLRELSDLLRTHLSSAATKQLDMGGVLSDLDTMLVALDKAEREGGVDKDQLKSFNSLILKTYRVIEDYVKGREGDTKNSSTEVSPYHRSNFMLSIVEPSLQRIQKHLDQTHSFSDIGSLVRAHKHLETLLEVLVTLSQQGQPVSSETYGFLNRLTEAKITLSQQLNTLQQQQESAKAQLSILINRSGSWADVARQSLQRFDSTRPVVKFGTEQYTAIHRQMMAAHAAITLQEVSEFTDDMRNFTVDSIPLLIQLGRSSLMDEHLVEQREKLRELTTIAERLNRLEREWM
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MVELLRDTLDVSVKEGIRFAELLMTNDGLKEFSEFKKEIKSKSETSMCSKHFCSHVLNVSCKTCMGNKSGSFCIECFMKGNHEGHEYVISQNVLPMCLCGHKELVDSKCFCHNHKGISENSTTKIFTEAQIKLFSQIFDIMVQFLVNVYPIELAYEVIKWLTSLANLGDSFLPLIAESFTKNNSENLIKIAESLSHSPSNSSNSILGLFIVLTSNTKFLRELGEKSIPLVSKFLEFTAENNKIIKSLFDVVALSYIDPEFSLYMIKEQNLIPKLIEQIIPFSKISQDKMIDIYCIPLFSIIIQSTSSLECAKYWAIENLDSRMVFIKLLETFQFACAIVRKTGDKEAYNNSSVQLQQISLTNIWKSIKNFVHGFTSLTTPDPAILYDIVRPAVKTFLDWYESRNIVKVESSVFGITFPGLNALTVEFSYSLPLNLFLHILIFSLYNFYKLDPNIFIREIGLQSLLPLCVHPIETVAAIGLAQANAYVRNAENVPKVANEINLSKQPPATLISFYSLFQYLISTENDATEFIATVVHSFGLSNWLATTQINQSIELQDQLILLFRFFIHLLSETIQKLFETEKMTRQRMSVIHFLYLHTSTAKEIKSQIAVFGMTAKEWNALLDEIAITVKNEKSTLYKLKPEFKSQRTPFFPFYLTTQFYSALAQELEGNQTKLVSTPDVEHLIFPNLPKFVSQKGFILFMDTIARNIAAMDEINSTMFQCFLALVHMGIKCSVYDKSDNFPNSLIEKDDSCLRILVNQKIMSQKTLGKPLLELFDIIQTEFPHLKEKIHEITSPFENADESNKTKINRKAIISQFMSRLEEFEQFNIESLSETSDDEEKEEKELVCAFCKKELTPGKDIYGILARIDPSYGDDVNEMNDITVPLFSFCPHYVHLTCFNESRPEGRLWTQCPLCRQQSSVLLPVLGISEEADKAEFPVLELFLRTAGHKCHPASLLSSYFRKKEITDRISKKRHYSQAEISAEKSICLIARGPPGDHPLPRKSQTPQIEQFIKLENKTEEEFWNNIKTIFGENPPRTFVRRCAMMINALNDKELIPIPEIQKIPNENEEKTEQEPSEKTEKPQNAMVIHGLTLSDRFEPKIFLDNAYPRFSQYFFAENDFQSRFMWLRSMDIARCLCCGEFFSISQKNNSLRYPYFFESKTGEARSHRCKHGLPIFLVLTGKSASAVIYYSHRTLMIEWGSIYLTERGDQDIGLSLMDDLYLNQNLLTKLKMEMYDGTIYRNAKRDADHVDLDFDFNLLF
The following text describes a protein:
Function:
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.
Subcellular Localization:
Cytoplasm.
Sequence:
MYSTSAKNEVVIKLVGKLSMEFEGIDQLKVRSIVEEVLYKYSILPEETGLMASDIEEKLQIYLASKKLDGLSIKTLRNYQYNLAIFANHLRKPLVAINTMDLRMFLAVRCKSMKQSSVNGQISILKSFFGWLADEEYIPKNPAKKLKQTKEPKRLRHAMTEEEIELLRQACKTDREKALVEFLISTGCRLSEAVGVNKDDINWYEMSLNVIGKGDKERKVYFSTKAKILLKKYLLARSDENIALFVTSKKPYGRLGGRSVQREIKKIASRAGINKSIYPHLFRHSFATNKLNAGMPMPVIQHLMGHESPATTQIYAELSEENIKHEYKKIS
The following text describes a protein:
Function:
Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4. Has a role in axonal regrowth following injury and synaptogenesis. Plays a role in modulating polymerization of neuronal microtubules. Also promotes tubulin post-translational modifications that protect microtubules. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis, and may also have a role in intraflagellar transport in cilia. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord; [Isoform a]: Has a role in synapse and axon development, and in axonal regrowth following injury; [Isoform c]: By forming heterooligomers with isoform a, acts as an inhibitor of isoform a activation. Its inhibitory function is independent of its catalytic activity.
Miscellaneous:
MISCELLANEOUS: [Isoform c]: Produced by alternative polyadenylation. The alternative polyadenylation site is in intron 7. In neurons, the usage of this polyadenylation site is regulated by the antagonist action of sydn-1 and ssup-72.
Subcellular Localization:
Synapse. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Cell projection, cilium. Note=Observed in the periactive zone of the presynaptic terminal which surrounds the synaptic vesicle clusters and active zones; [Isoform a]: Synapse. Cell projection, axon. Note=Co-localizes with isoform c in synapses and axons; however, isoform a localization is independent on its interaction with isoform c. During axonal injury, recruited to the injured site; [Isoform c]: Synapse. Cell projection, axon. Note=Co-localizes with isoform c in synapses and axons; however, localization is dependent of its interaction with isoform a.
Domain:
[Isoform a]: The C-terminal hexapeptide motif is required for homooligomerization and for its activation; [Isoform a]: The C-terminal domain is important for localization to synapses and axons.
Sequence:
MTSTTMVTTLDLVTPTSEEQPGPAPESSDFSTVVLSPDGSELVTQSAPNTPIQHREQANAEFGQKEGSPDPKNMVAATGNASKPSLNSFYADGLGQLRNGLFSCFQPVFGYFGTKTTVEIEKSEDELWEIPFDAISELEWLGSGSQGAVFRGQLENRTVAVKKVNQLKETEIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEYCSKGQLCTVLKSRNTITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHMQKKMDSTMMSFCGTVSWMAPEMIKKQPCNEKVDVYSFGVVLWEMLTRETPYANIAQMAIIFGVGTNILSLPMPEEAPKGLVLLIKQCLSQKGRNRPSFSHIRQHWEIFKPELFEMTEEEWQLAWDSYREFAKCIQYPSTVTRDHGGPKSAFAMEEEIQRKRHEQLNHIKDIRNMYEMKLKRTNKMYDKLQGCFTELKLKESELAEWEKDLTEREQWHNQNSPKAVAAPRAQLRGYPNEGYDDMSSDEDVQPCRGSPYRCSNTSSSSGVQSSPFSRQSSSRSSAGQQTRRSEGANPPKILRNDAIRHSGSYWETLGGARGSPARDSGFSQDSGMWSAGAGSCTAINGGGQQVCYSQTLYRNGDGRWSDGRIASRRRVSTSVNKSTAVPGQPVFFTRDSPSRVPHGVISCSSPRSSSKLNRSSYPSRNAPHQLEDGCCCAHARAPRAKSIAVPMTSSSRARSPTPYDNDFENAESFVDPESPKNLKNLEKIVNLPESTSYDEALCNSDVTMNPIYTSPITTYSNPCHVELVDEENANDVDLTSSMDSRRSRSDDADVESSEEDEGNGNNILNTSMESEDLRYRIDTSQSTMMSSLERSLEIGATRSDGLSDNEMRVQAVKMSIKTHRRTGSNPQALIHQCIDEYTTSATDDSDDAGAVRI
The following text describes a protein:
Function:
Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEKDKPVSVKDAVFKLQMSLLEGIQNEDQLFAAGSLMSRSDYEDIVTERSITNVCGYPLCSNALPSDRPRKGRYRISLKEHKVYDLHETYMFCCSNCVVSSKAFAGSLQAERCSGLDLEKLNNILSLFENLNLEPAENLQKNEDFGLSDLKIQEKTETSSGEVSLEQWAGPSNAIEGYVPKPRDHDSKGLRKNVKKGSKAGHGKPISDINLISSEMGFVSTIIMQDGYSVSKVLPGQRDATAHHQIKPTAIVKQLGKVDAKVVRKDDGSIQDLSSSFKSSLILGTSEKEEELAQSCEAALKSSPDCAIKKKDVYSVSISERQCDVEQNDSAKKSVQVKGKMSRVTANDDASTSNLDPANVEEKFQVEKAGGSLNTKPKSSLKSAGEKKLSRTVTWADKKINSTGSKDLCGFKNFGDIRNESDSAGNSIDVANDEDTLRRASAEACVIALSSASEAVASGDSDVSDAVSEAGIIILPPPHDAGEEGTLEDVDILQNDSVTVKWPRKPGISEADFFESDDSWFDAAPEGFSLTLSPFATMWNTLFSWITSSSLAYIYGRDESFQEEYLSVNGREYPCKVVLADGRSSEIKQTLASCLARALPTLVAVLRLPIPVSTMEQGMACLLETMSFVDALPAFRTKQWQVVALLFIDALSVCRLPALISYMTDRRASFHRVLSGSQIGMEEYEVLKDLAVPLGRAPHISAQSGA
The following text describes a protein:
Function:
Protein transport. Probably involved in vesicular traffic from ER to Golgi.
Sequence:
MALDFAATYKVLVLGDSNVGKTCIVHRYCDERYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAGQERFRTLTTAYYRGAMGILLMYDVTSLESFNNLSYWLRNIQENAAPDVVKVLAGNKCECNPPQRAVDKERGEKIAENFDMPFFEVSCKQNINIEDAFLTLARKIREQREHRGENFDDGDRQKGLQDMIKNGPGSNGLGPFTLGSGGDGGRCSC
The following text describes a protein:
Function:
Dolichyl-phosphate beta-glucosyltransferase involved in the glycosylation of glycoproteins through the synthesis of dolichyl beta-D-glucosyl phosphate which serves as a sugar donor for transfer of three glucose residues to the Man-9-GlcNAc-2-PP-dolichol precursor to N-glycans.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MNDLPPIANLISNILFVLLIITFLYALCSRFVSDKTLYDYTILPTNDPEKINYYIEPSPSPKEKIPFPTVFSPSEVYTTFVVPAYNESKRITPMLDETVAYLERRASENPEFTWEIIVVNDGSKDNTAEIVTNYAFKHPQIRLLNQPKNMGKGAAVQAGCLHSRGELILMVDADGATKIDEFEELEKKIKSLTTINKEAIVVGSRAHLEGAEKANRTPLRKFLGLGFHMLITIAGVHGIKDTQCGFKLFTREAARWLFPNQHVQRWCFDPELLVIAQSRQMEVAEVPVEWNEIGDSKMKISGMIKMAIDLVQIAIYFRAGLWTVKDKADTPISDFEV
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MFKRKKNAGQKRTTIIDSDSSSEGSGDESALSSAFKRRKNDTQKRTTPTSVATSTKVRAPSFSSTIDHSHSRNLSKTDEATKETILYAKDDSDDSQKLSKGPYKVPFSKPTTTTTVGLKASSNIKSTTSQDYQPDVCKDYKLTGFCGYGDSCKFLHMREDYKAGWQIEREWEIKNREDDPPRDAGGVSRDADTATSRADSGIPDTCPICQGEFKSPVVTQCCHYFCEKCFLAKHKKKQNCFVCGKNTNGVCKPFKR
The following text describes a protein:
Function:
Displays esterase activity toward palmitoyl-CoA, malonyl-CoA and pNP-butyrate.
Sequence:
MKLNIRAQTAQNQHNNSPIVLVHGLFGSLDNLGVLARDLVNDHNIIQVDMRNHGLSPRDPVMNYPAMAQDLVDTLDAQQIDKATFIGHSMGGKAVMALTALASDRIDKLVAIDIAPVDYHVRRHDEIFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQFLLKSFVDGEWRFNVPVLWDQYPHIVGWEKIPAWDHPALFIPGGNSPYVSEQYRDDLLAQFPQARAHVIAGAGHWVHAEKPDAVLRAIRRYLND
The following text describes a protein:
Function:
Guanyl-specific endoribonuclease which cleaves the phosphodiester bond in single-stranded RNA between the 3'-guanylic residue and the 5'-OH residue of adjacent nucleotide, resulting in the formation of a corresponding 2',3'-cyclic phosphate intermediate. Essential role in male and female postembryonic germline development; maternally provided protein maintains a population of proliferating germ cells and zygotic expression is required for correct oogenesis (By similarity). Together with the P-granule component pgl-3, is involved in the formation of P-granules (By similarity). Together with pgl-3, probably recruits other granule components such as pos-1, mex-3 and glh-1 to P-granules (By similarity). In addition, may act redundantly with pgl-3 to protect germ cells from excessive germline apoptosis during normal oogenesis and development of the two gonadal arms (By similarity). This may in part be through regulating the localization of sir-2.1 which is involved in germ cell apoptosis (By similarity). May protect somatic cells from excessive apoptosis during normal development (By similarity).
Subcellular Localization:
Cytoplasmic granule. Note=Localizes to P granules in germline precursor cells. Localizes to P granules in germ cells at all stages of development except in spermatogenesis. Co-localizes with pgl-3 in P-granules, but localization in P-granules is not dependent on an association with pgl-3.
Domain:
The dimerization domain also acts as a hinge; changes in its structure probably impact oligomerization and RNA-binding; The RNA-binding RGG-box is required for the recruitment of some P-granule components such as pos-1 and probably mRNA, but is dispensable for granule formation.
Sequence:
MENNKRGVVEAKGIKSHYFQTLANYVSNNLELLHNNPKQANSFAASVFGSTAPIDEKDLLDLLVPSDANADALAAGMDCCLLLGEKYRPHFDAAVQQLARLGRTHDVATVIDDEKKFTALSKKTKLKKTDEAKILQAFFKIHSTEDEEKFEAISELCQLDLDFDAYVFIKALTLENEENQELVETIKDNLVEAWNKSNPLLVKLLLEGVKEQDPVDKFTYLLLQPLTEATLSDAVNFIVEKYSAELPDEGDASLVVRSQLGCQFFFLVTRTLAHDQRELAKLVQTLIPRPVRLEVFPGLQRSVFKSSVFLGHHIIQIFMGCEFCSIQSIKNTMFSAKKPFQDWSFVGLAQDFECPWRRLAIAELLKKFSVSVVEKVFDNPVALIPQHESDNEALIELVTNALRFALWIVEFYETETNEKSIKELAFLDHSSKTLLIESFTKFLQGKDVKDQDHLKRIIDALEKSRTQETKSNLEYSREEIKTKMPSSSSAKAQVLHGLNTSAAAGLIVPSLSLLEIPVDEVDSTSHLTTSKDIGQGVFVKAQDTVTEKQKEAPLVAQQTAFHHEPQTATLVPPSPNEESMAAESISTDGWDSPTKSVVLPLDDMILEEEERDALKPDSVNSHRSEETTPVPEQLPQETSERVTSPPPGERSRTAWGDGDATPMILATPTNDYKVSGFGGAKLAKGFGTMGSTGGGFGGGGGGGSYGGRGGYGGGDRGGRGGGFGGGDRGGRGGYGGGDRGGRGGGYGGGDRGGYGQRGGYVAGGDRGGRGGYRGGGGNF
The following text describes a protein:
Function:
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subcellular Localization:
Mitochondrion.
Sequence:
MLGSVLLKLKKLQLHGLKSKGISLKYFSYKVPDKPTWTAVNQSKLPEPDKVDQKTLLLLERLSLVDFRTQEAVERLAEAIKFADQLLDVDIDGIEPMYTVLENMPCYLREDVATESSCKEDILRNAKETFEDYFIAPPGNIPLTASLIGEIQLENKEKNLKKSEVL
The following text describes a protein:
Function:
May serve to lubricate the movement of the cellulose microfibrils during cell growth and wall extension and/or may serve to maintain the fluid state of the slug cell wall.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MKFNTIFLVLSIVKFILISAQSCPFSQSIINGASATFYTAIDAGNCGFEKLNGPLGPGNYMIAALGSKLYQNGAQCGQCFKISNSKNASVTVMATDSCHDAGYCQRDNHFDLSPAAFSILGPQSQGVLDGLSYVKVPCEVSGNVKIMMKDGSNDFWTSFFVFNSKVIIKQVSIKLSNSNQFVPLSQTTYNYWPTSITGGQFHVRIESIGGEFIYVTIPKVESRKVYETSGQFSTSCSNLNENNPINYKPQTFNSQQTSNNQNSNTQTPTKQPSPNSQNFIPSYCQQYIQKPNYIFAKESKEMLVLNENENIESNSLKLLPNFLLLILIILLNINF
The following text describes a protein:
Function:
Essential for normal spermatogenesis and male fertility.
Sequence:
MHYIKTWSLLGEMSEKLRRCRKELTAAIDRAFEGVSYSQECTGQQRLELSAAPLSFSLPVHRLLCRRHPLAACSSAAPFAAVPCAPENENPAFATNHAPVNAKPHALCPERKPLTSKENVLMHSSILAPERESWRTAGEGENWRKENLRKDMERDLKADSNMPLNNSSQEVTKDLLDMIDHTSIRTIEELAGKIEFENELNHMCGHCQDSPFKEEAWALLMDKSPQKATDADPGSLKQAFDDHNIVETVLDLEEDYNVMTSFKYQIE
The following text describes a protein:
Function:
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MGWTAHTHTHTLYLKIFVLYWSVSRARATTTSSRLSRTSSHCDVCSRAHTECCVPVCALFTLLFRFCIHRKASVPQPLSASTCGSCVPTVEPPFLVFAHRPTSHTHRQTERHLPCIMSISVRIRTPKSSTPEQVELNSSGTWGEAAVLLSRKSEVALERLRVLAGFPPKAVDLAADSPLSALKLRANDMLIVQEGEAKVQLGNTGERYVPPAPERAHLTRRRCPADNSCLFHACAYVLRDKSRTEGPQLRQECVQAVLDHPEMFNVNTLGMDPLAYASWLSQKDTWGGAIELEILSFLYKTEMFALDLQSVTVQRFGTGLGYTVRAFLVYTGNHYDCIAMNPVYNSASEREDQTLFSSRDENVLVRAKRFVAEEGQKMKEGKAT
The following text describes a protein:
Function:
May regulate trafficking and current kinetics of AMPA-type glutamate receptor (AMPAR) at synapses.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MARAGARGLLGGRRPPGLRLALALRLALLLARPPSGRAGAPEAQGPAAPGTTAPEGGDRCRGYYDVMGQWDPPFNCSSGAYSFCCGTCGYRFCCHDGPRRLDQSRCSNYDTPAWVQTGRPPARARDTAAPRDPGRERSHTAVYAVCGVAALLVLAGIGARLGLERAHSPRARRTVTRALTELLKQPGPQEPLPPTLGPPLGGCVQVQMGDGLPRGSPHNSADKKRLNNAPRGSAAPGPPRGPRLQGGGSLTLQPDYAKYATFKAAALKAAEAAPRDFCQRFPALEPSPRQPPARAPRPSPDLPAPLDACPWAPPVYAPPAAPGPYAAWTSSRPARPAPLSHPTARAFQVPRRPGHAARRQFSVKMPETFNPQLPGLYGSAGRGSRYLRTNSKTEVTV
The following text describes a protein:
Function:
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
Subcellular Localization:
Cytoplasm.
Sequence:
MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFCKHGEQYFRNLEFTCLQECINTADIIATGGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISEIYYELLNLIKASDQY
The following text describes a protein:
Function:
Receptor for basic fibroblast growth factor.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MSLPRCPRTRTVMFSRTLTRCYPQRTLWIAILCVICSWTLSTAGATTIRDKEVKPDAPQDLTAIPVKAEAIVLTWKKPLKGQTDGYIVVYCLKRNKGNGCERQKIEGGNVTEVEVTNLYANHTYQFQVQSWYSDHPKGASTGYIEASGTPPIPPTLRRNFKGLVEKSLGFEHKIPCPVKADPRPYTRWLKNGTDLTPNDPDDNVSFTKTSIVFKRLRFSDAGLYTCVASNFFGQPIHVNFTLIVVDTHSESYAESSVLESFSSLELETGPYNETEEEETHFPRFTDTERMEPEKPLPSNTKVRLECGARGTPTPNITWIKDGVQKWKINVIRPTRVEEKGFVLIIRRAIVRDTGKYTCIVSNQYGTIEHTYDVKIRERLPVKPIMSPMKNVTATVGSNTSFVCRVVNDLTPHFAWMRFNGTNNTKQRLTDIDDHISILQQRWVEEPMLTCDEFLDVFYQNQSKRMLECLHLIQLETQGGMEEANQLKLYNVQYEDEGPYLCVAGNFYGMSWEGAYLDVVEPTTQAPVRTNPPAVYIPNNMQPTSKTQLIIFSVVGFVVVLILVTCIAILCKQTQVRHRRPSDKPDISGPKHLYRQTSVDSTQSIAPLFGGRNRLTSSLTVISEYDIPLDPEWEFPRDRLTVGKTIGEGAFGKVVIGEAVGIVCQEKTSTVAVKMLKANAMDREFSDLISELAMMKMIGKNPNIINLLGCCTQEGPPYVIVEFAHHGNLRDFLRSRRPPEEYEKSILLTTSQTLTNKDLMSMAYQVARGMDFLASKKCIHRDLAARNVLVTEDFEMKICDFGLARDIHYIDFYRKTTDGRLPVKWMAPEALFDRMFTTQSDVWSFGILLWEIMTLGGTPYPSVPVEQMFDYLRSGKRLEKPQNTSLEIYHILCECWRTSPGQRPTFCELVEDLDRIISVSSNQDYLDLEAVGDAPVKTFQESERMAFMGFRAPLSPQVYYKVPQTRDCCPYAN