lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by uba4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
Subcellular Localization:
Cytoplasm.
Sequence:
MSTSTTFQIHYFASASTYTGKQTERLPAPLPLPQLFDTLESMYPGIKEKVLTSCGVSLGDEYVDVEADIQVMIHPGDEVAVIPPVSSG
The following text describes a protein:
Function:
Functions as a part of the autophagy-specific VPS34 PI3-kinase complex I that plays a role in autophagosome assembly. This complex is essential to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre-autophagosomal structure. By binding to atg8 at the phagophore assembly site, atg38 helps establish a positive feedback loop for recruitment of phagophore assembly proteins, including atg8.
Subcellular Localization:
Preautophagosomal structure membrane. Cytoplasm, cytosol.
Sequence:
MVRYSLRKAHEYARDGENQEVLGEISQAIMYYGLAKSQFEKICQNTAQPLIKRCANNQIEELMVRIRELRESLPNKQTPISMSMSTRLSPMYTSSLTPRFTSNSMVLPGDHNTTVRLKPSFREALMEDSEDDLYQMYSKFEMQVKKLSTNYGLAVAFSIVPMDDDQPSPSIFSSDESFLIVEGDDFSLGNSVEEDANATSKEDPAYQNTNEQIQPLSNFDISQQEYLNNTRIPYENEDLHLQHITQGTTDDNNVSKFLIPSYNDAKELSEEEMGRSHKREESFKRAFGHASSSESSIGEITDSREDIQSNRLVNGSWENNDFTKEINNNFPDRSETPTLQTIEAPTKLMKYTRRKSLFRFPFFRSISGKKKEEPMESGTDSLESSTAQITVDSQLKIKQLETQIATLQKQLEQFQTSTLDQDLH
The following text describes a protein:
Function:
Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May play a role during neuronal differentiation and development. Shares a similar tissue distribution, co-localize with, and interact with isoform 1 in NT2 cells.
Subcellular Localization:
Cell projection, neuron projection. Cell projection, growth cone. Note=In undifferentiated neurons, located in the actin-rich regions of the cell body. In differentiated neurons, located in the actin-rich regions of the cell body and primary neurite processes but is almost absent from secondary extensions arising from the primary neurite. Also found at the actin-rich distal end of growth cones (By similarity).
Sequence:
MLHLKVQFLDDSQKIFVVDQKSSGKALFNLSCSHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQVKNPKEIVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSELGDFHEETDRKHLAQTRYLPNQDCLEGKIMHFHQKHIGRSPAESDILLLDIARKLDMYGIRPHPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMASRDACKAFWKTCVEYHAFFRLSEEPKSKPKTLLCSKGSSFRYSGRTQRQLLEYGRKGRLKSLPFERKHYPSQYHERQCRSSPDLLSDVSKQVEDLRLAYGGGYYQNVNGVHASEPVLESRRRNSALEVTFATELEHSKPEADPTLLHQSQSSSSFPFIYMDPVFNTEPNPNPDPRDIFSERSSLSSFQTSCKFSGNHMSIYSGLTSKVRPAKQLTYTDVPYIPCTGQQVGIMPPQVFFYVDKPPQVPRWSPIRAEERTSPHSYVEPTAMKPAERSPRNIRMKSFQQDLQVLQEAIARTSGRSNINVGLEEEDPNLEDAFVCNIQEQTPKRSQSQSDMKTIRFPFGSEFRPLGPCPALSHKADLFTDMFAEQELPAVLMDQSTAERYVASESSDSESEILKPDYYALYGKEIRSPMARIRLSSGSLQLDEEDEDAYFNTPTAEDRTSLKPCNYFLA
The following text describes a protein:
Function:
Acts as a critical regulator of DNA damage response (DDR) signaling via specifically regulating phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Localizes mainly in cytosol and to a lesser extent in the nucleus.
Sequence:
MAALFPPPPGPRFVLRGTQSAVNTLHFCPPSQAAGNPLLFSGSQNGLVHIWSLQTRRIVTTLNGHGGQGVIWLKTLPQGHQLLSQGRDLRLCLWDLEEGRNTIMDSVQLDSVGFCRGSILVRGQQCWMLAVPGKGSDEVQILEMPSKTSVCTLKPEADARPGMPMCLGLWQTNSSLRPLLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGLDFDSQKAKGISGSAGKVLAVWSLDDQQSLQVKKTHELTNPGIAEVTIRPDHKILATAGWDHRIRVFHWRTMKPLAVLAFHSAPVYCVAFAADGLLAAGSKDQRISIWSLYPCP
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
Subcellular Localization:
Cytoplasm.
Sequence:
MALKKEGPEFDHDDEVLLLEPGIMLDESSADEQPSPRATPKATTSFSSKQHKHIDYTRALDATQLYLNEIGFSPLLTPEEEVHFARLAQKGDPAGRKRMIESNLRLVVKIARRYVNRGLSLLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHVVKELNVYLRAARELTHKLDHEPSPEEIANLLEKPVAEVKRMLGLNERVTSVDVSLGPDSDKTLLDTLTDDRPTDPCELLQDDDLSESIDQWLTELTDKQREVVIRRFGLRGHESSTLEEVGQEIGLTRERVRQIQVEALKRLREILEKNGLSSDALFQ
The following text describes a protein:
Function:
Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates. Has equal high activity toward ADP/ATP, GDP/GTP, and UDP/UTP and approximately 50% less toward CDP/CTP and thiamine pyrophosphate. Has no activity toward GMP. Required for Golgi glycosylation and cell wall integrity. Together with CDC55, required for adenovirus E4orf4 (early region 4 open reading frame 4) induced toxicity, the apyrase activity is not required for this function. Plays a role in sphingolipid synthesis.
Miscellaneous:
MISCELLANEOUS: Present with 450 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus. Membrane; Single-pass membrane protein.
Sequence:
MLIENTNDRFGIVIDAGSSGSRIHVFKWQDTESLLHATNQDSQSILQSVPHIHQEKDWTFKLNPGLSSFEKKPQDAYKSHIKPLLDFAKNIIPESHWSSCPVFIQATAGMRLLPQDIQSSILDGLCQGLKHPAEFLVEDCSAQIQVIDGETEGLYGWLGLNYLYGHFNDYNPEVSDHFTFGFMDMGGASTQIAFAPHDSGEIARHRDDIATIFLRSVNGDLQKWDVFVSTWLGFGANQARRRYLAQLINTLPENTNDYENDDFSTRNLNDPCMPRGSSTDFEFKDTIFHIAGSGNYEQCTKSIYPLLLKNMPCDDEPCLFNGVHAPRIDFANDKFIGTSEYWYTANDVFKLGGEYNFDKFSKSLREFCNSNWTQILANSDKGVYNSIPENFLKDACFKGNWVLNILHEGFDMPRIDVDAENVNDRPLFQSVEKVEERELSWTLGRILLYASGSILAGNDDFMVGIAPSERRTKLTGKKFIPGKLLESDQLRKQSSSLSNKGFLMWFAIICCIFYLIFHRSHIIRRRFSGLYNITKDFKTGIRRRLKFLRRSDPFSRLEEGELGTDVDGFKDVYRMKSSSMFDLGKSSATMQREHEPQRTASQSANLAPSNLRPAFSMADFSKFKDSRLYD
The following text describes a protein:
Function:
Mitochondrial dehydrogenase involved in pathways of fatty acid, and steroid metabolism. Versatile enzyme presenting two types of activity; L-3-hydroxyacyl-CoA dehydrogenase ((3S)-3-hydroxyacyl-CoA dehydrogenase) activity and hydroxysteroid dehydrogenase (HSD) activity with a wide substrate spectrum. As a (3S)-3-hydroxyacyl-CoA dehydrogenase, it functions in the third step of the fatty acid beta-oxidation pathway, a major metabolic process in which fatty acids are oxidized to provide a significant source of energy, while also generating acyl-CoA metabolites used by many metabolic routes (Probable). As a HSD, it functions in the degradation pathways of glucocorticoids and sex steroids and epimerization of bile acids; catalyzes the beta-oxidation at position 17 of androgens and estrogens, has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone, and carries out oxidative conversions of 7-beta-hydroxylated bile acids like ursodeoxycholate or isoursodeoxycholate (also known as 3-beta,7-beta-dihydroxy-5-beta-cholan-24-oate or 7-beta-hydroxyisolithocholate, respectively). Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. Essential for structural and functional integrity of mitochondria. Required for cell survival during embryonic development. May play a role in germline formation; In addition to mitochondrial dehydrogenase activity, moonlights as a component of mitochondrial ribonuclease P, a complex that cleaves tRNA molecules in their 5'-ends. Essential for the structural and functional integrity of mitochondria. Function is essential for pupal development.
Subcellular Localization:
Mitochondrion. Note=Localizes to the lipid droplet fraction in early embryos.
Sequence:
MIKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVTSEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDGALRMMP
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSELELEEVERSLRNAKGVPAADKLIKYLRLVRELHVRDSPTVARYGNILLRHYKSHLSEEELWLVHEQVAVAALDAHALPFAASVIKAINRRFPDSVRARRLQGMYFEAAGDFPRAEEMYRDVLATHPNNEMALKRMVSLERSRGNPAAAIEALRRYLDTFGNDKDGWEELAELYLEVLNYRQAAYCYEELIMMNPGNSSFYTRYADVLYTIGGATNYKTARSYYAKAIELTAGGSLRALFGVLACAAHITDKVALQDARSRAQIELPEASTQALLRIYRTHAPDKLPFVEPLLAKLAAGQPGAQ
The following text describes a protein:
Function:
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
Sequence:
MTKPSAVNIHRTNPPDWFKQADFGIIIHWGPYSVPAYAPVNIPDYGTLIKTKSLGYLFEHQPYAEWYGNSMLLPNSPVAAYHRTHYGNTSYADFAKTFKQTAQNVDVQAWAEAFANAGAKYVVIVTKHHDGFVMFDPHTKNPYEPDYHLNFDFVGELAQAVRAHGMRFGTYYSSLLDWTFPHLPIKDYGSFLLGNDKSQTYKDYVWHQWHELIDRYHPDVLWSDIGYPDDHRLETLFKYYYQQVPEGLVNDRWQQFPDWMRTSWIRPIFNLVAAQVIKRDRHHSDDLSEVKYYDYRTLEYRTDWPQTNRYFEMTRGMDKSFGYNSLSRPEDYITADDIKQLIAELRSK
The following text describes a protein:
Function:
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF9 is also a component of the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TAF9 and its paralog TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. Essential for cell viability. May have a role in gene regulation associated with apoptosis.
Subcellular Localization:
Nucleus.
Sequence:
MESGKTASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKASTSAGRITVPRLSVGSVTSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPTSQSPAVKASIPATSAVQNVLINPSLIGSKNILITTNMMSSQNTANESSNALKRKREDDDDDDDDDDDYDNL
The following text describes a protein:
Function:
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MVKARKEGKVSKKLKQKPDYGPVKNRHTFRGSNHSMNPDRKADSKDKSQRSKATINRLRMYKSFKPIRDSKGKIVKAAPFQDTLASGTQARIEPNRKWFGNTRIIGQEQLQKFQANLGKVLSDPFQVVMKQTKLPISLLQEKAKTQRVHVTETESFEYTFGKKALRKKAKLNDATLEEMTRSAEDREVKYKPELDLSREKELGDRPENQNPLFRAGQSNRVWGELYKVIDSSDVVVQVVDARDPMVSLQKLYENIIVRSKMNVFSMSTKTNSLEKTHNVRMKVFPSILPHFFLSCFNSKRERKRMGEKQRRENLYIDESKNSFSRSLCAISGTRCRHVEEFLRKEKPHKHLVTVINKVDLVPTWVTRKWIGELSKEMPTIAFHASINNSFGKGAVINLLRQFAKLHPDRPQISVGFIGYPNVGKSSLVNTLRKKKVCKTAPIAGETKVWQYVMLMRRIYLIDSPGVVYPQGDTETQIILKGVVRVENVKDPENHIQGVLDRCKPEHLRRQYGIPEFSGVDDFLTKIAIKQGRLLKGGDPDIVAIAKVVLNEFQRGKLPYFVPPPGCEERAKKDYEEAPINEKCADDDEQLPPDAQLELDDVARNGGPEDDDAIDDEEEEEMTEIGSTCSGLTDLSGISDLAEDLEEVEDVTEEPTSSDAADKKKNDVASVRTRGKRGGKKANKAKLSGKTIVQAASEKKDKSVVDFAKPGAQKTNMWRKKLEKRRKIKHQK
The following text describes a protein:
Function:
Involved in the initial differentiation of the proplastid during the embryo development. Also required for correct cotyledon, true leaf and cauline leaf margin development.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MVSSVLSIPPQTCLLPRLPISDSVNCKSKIVYCLSTSVRGSSVKRQSTARTRSFTETNRRTPSVQSKHEFWEDPDDGSDSENEYEGEEEDGIGNDLDNESDWEDDSRVQKLTTTDNYEEELAKEVEQLLEPEERVILQQNEKPNLKMISTKSWKPLQTLALSMQIQLMDNLIENGLDIDDVDKDNQTALHKAIIGKKEAVISHLLRKGANPHLQDRDGAAPIHYAVQVGALQTVKLLFKYNVDVNVADNEGWTPLHIAVQSRNRDITKILLTNGADKTRRTKDGKLALDLALCFGRDFKSYDLVKLLKIMPTGDI
The following text describes a protein:
Function:
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
Subcellular Localization:
Nucleus.
Sequence:
MTIELEMAGRVTVRLEHPRNVMYVRVLQVWKENATEHESKMVYALFNAMKAIKACPLSIDGFEGLKRLNGVGDVIASRLEACWEILSFEMGDDIKSVTKVKETLTKEKTVYIFDATKKVGKHKGRVPSLKQAPPATSKAAPKRLSSSQIPSTSRADDDEFVEKDDVVPVKMARFNSDPMLSKASSRSNSGQTTSNGPSTSISAAGTGGDSDDDDEDEGGMEYVCIEPRDNVEVILIMDNAEKNGNAKSSVVDLLEKKDIRVDRRRLSIGDYMWIAKKIDGTEMCMDWVVERKTWGDLDSSIKKSRYQEQKQRLRAAPFTNRVYLIEGQREGQSHLQQALVTTMVHDNFLIQRTLSCHKSAEFLVSLTKRLQQQVRSEKMVRPTFASVQSFSKKSASIDRLSDIWTRMLMVVPGMSADSAKLVAERFPSIKALMTLWKEEADPEKRLLKEVPSLGRVQAANISLFFELGMKK
The following text describes a protein:
Function:
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
Subcellular Localization:
Cytoplasm. Mitochondrion inner membrane. Mitochondrion matrix.
Sequence:
MLIPSRSSTRLRTSRLFIYRRRMFSEYRSRGYEEAIVALNSLQSNASVLAAIQAAGPQPSERVFGQTNYYLRRLGYKPKDLNILNAIHISGTKGKGSTAAFCSSLLNTINPSAKVGLFTSPHLVAVRERIRINGKPISEEMFSKYFWELWERFEDGNGEPARPDLPIRPAYFRYLTYMAYHAFIAERVDATVFEVGVGGLLDPTNLIPSPIVTGVSSLGIDHVNVLGHSIAEIAGHKGGIFKPGVPALTVQQQYPETINVLRARALELKSSSFTIIPRRPDLDQLKIGLAGSHQKHNASFAIALVNTFLGSPRLPHSYFKHASPIRDTTASDTPSDLLPLLPSDPSPTLPESVDPRQPELPKDLVQPELSGLFKAGITNTRWPGRCQTIVDPVRSGVTWFLDGAHTVDSLELCGQWWNQQLESSSSSSSTHPTSNQPRRILIFNCTFGRKARDLLEGLIKPLSQNLHSGFFDQVIITSNTTYSDGKFKTQDTLSDPDQRIQQEIAEAWTSMSNSTKNVMVVNSIEQAVDEVARQNLLSGSTSVLVTGSLHLIGGLLDVLGLEDAL
The following text describes a protein:
Function:
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. PatI catalyzes the conversion of m-hydroxybenzyl alcohol into gentisyl alcohol. The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units. The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol). These first reactions occur in the cytosol. The intermediate m-cresol is then transported into the endoplasmic reticulum where the cytochrome P450 monooxygenase patH converts it to m-hydroxybenzyl alcohol, which is further converted to gentisyl alcohol by the cytochrome P450 monooxygenase patI. The oxidoreductases patJ and patO further convert gentisyl alcohol to isoepoxydon in the vacuole. PatN catalyzes then the transformation of isoepoxydon into phyllostine. The cluster protein patF is responsible for the conversion from phyllostine to neopatulin whereas the alcohol dehydrogenase patD converts neopatulin to E-ascladiol. The steps between isoepoxydon and E-ascladiol occur in the cytosol, and E-ascladiol is probably secreted to the extracellular space by one of the cluster-specific transporters patC or patM. Finally, the secreted patulin synthase patE catalyzes the conversion of E-ascladiol to patulin (Probable).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MDILQLAPTHLLAILLSSTSALFLITYLLRAGHRPSDLPNGPPTVPLFGNELQVPKSDAHFQFSRWAKEYGGFFTLKRYNNTTIVISDQKLIKTLLDKKSNIYSHRPASLVSHLITQSDHLLVMQYGERWRMLRKTIHQYFMEPRCERDHWKVQEAEAKQMLHDYLTMPEDHMLHPKRYSNSITNSLVFGIRTKTVHDEYMKKLFYLMDKWSLVQELGATPPVDSFALLRYVPQWMLGNWRNRAVEVGDLMQSLYQTVLDQVKERRQRGIQRDSFMDRVLDTLKQTPLSENELRFLGGVLMEGGSDTSSSLILTIIQAMTKYPEVQAKAHAQIDSIIGHNRSPAWSDWSKLPYINMIIKESHRWRPVSPLGVPHAVAEDDHIDGKLIPQGSSIVLNVWGMHHDSDRWQEPEHFQPERFADFPALASGYAGSERRDHLGYGAGRRICPGIHLAERNLIIGIAKLLWAFEFLEPLGSDSDISAHSGASKGFLHCPKDYGCVIRLRSPEKRETIMREFAEAQEVFARFD
The following text describes a protein:
Function:
Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAAMATALTSLSSSPKPTFLDHNKSSFSGTPIPSRFTPIKSSSHNSAISMSLTPPYDLQSFKFQPIKESYVSREMTRRYMMDMITYADTDVIIVGAGSAGLSCAYEISKNPNIRVAIIEQSVSPGGGAWLGGQLFSAMVVRKPAHRFLDELGIQYDEQEDYVVIKHAALFTSTIMSKLLARPNVKLFNAVAAEDLIVKGNRVAGVVTNWALVSMNHDTQSCMDPNVMESKVVVSSCGHDGPFGATGVKRLKSIGMIDSVPGMKALDMNTAEDAIVRLTREIVPGMIVTGMEVAEIDGAPRMGPTFGAMMISGQKAAHLALKALGQPNAIDVTFSKAERVQPEFVLAAAETEETVDA
The following text describes a protein:
Function:
Positive regulator of brassinosteroid signaling.
Subcellular Localization:
Nucleus.
Sequence:
MPVSSHQLISTPGTDQSEFLETKKRKALDVSESSSFNSSPQVSENGKGKNNSRRGKRTKSKEDDEKPKEVVHVRARRGQATDSHSLAERVRRGKINERLRCLQDIVPGCYKTMGMAVMLDEIINYVQSLQNQVEFLSMKLTAASTFYDFNSETDAIETMQRAKAQEAKEIERVMKEGYGGLTNFHPTWSL
The following text describes a protein:
Function:
May be involved in strigolactone signaling pathway (By similarity). Essential for plant responses to karrikins, a class of butenolide compounds, structurally similar to strigolactones, released from burning vegetation that stimulate seed germination and enhance seedling photomorphogenesis. Mediates a specific perception of karrikin. Required for the establishment of symbiosis with the arbuscular mycorrhizal fungi (AMF) Rhizophagus irregularis and Gigaspora rosea. Karrikin binding induces a conformational change (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MGIVEEAHNLRVVGEGKRGVIVLAHGFGTDQSVWKHLVPHLVADYRVVLFDTMGAGPTNPDYFDFSRYATLEGYALDLLAILQELRVASCIYVGHSVSAVIGAIASISRPDLFSKLVLLSASPRYLNDVDYYGGFEQEDLDELFEAMGSNYKAWCSGFAPLCVGGDMESVAVQEFSRTLFNIRPDIALSVAQTIFQSDVRSLLPLVTVPCHIVQSTKDLAVPVVVSEYLHKHLGGDSIVEVMPSEGHLPQLSSPDIVIPVLLRHIQHDIAV
The following text describes a protein:
Function:
Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
Subcellular Localization:
Peroxisome.
Sequence:
MEPIEKEGYPICLVACRSRNQPLTPEKGYQSAVTSTSHSGSLQDISSQVGSSGVIVDYQKGLVITTALPFTEFIPSEQGGRNDNQSNSEGELDNCVNHYSGNELKELSVSVILQSSRINEKGKAKENFHSTANYNRHRPRANRVLSALPHPGNLTTSCIEDNATESFEVHDARVVLLWRCASLDDEMKSLMPSADGWELDYGEKKGEIGSSSHLAGGKDMVEDGDEEERKDKSQRNLLSWFALLQVDGGLHVPTGQQLKIVPSTSLRLAQPVTGCGTPFATLSPSIFYNSLSTGIITKRNGRDLVMTDARCMPGTEGGGLFVMDKKQRYLAAMIISPLCWKANEWIGLTLACSMTAVLDSLQGLTSIDLSMIRSTNCEDISYTSHQMHLQNQVDVKRFQSIVLLRVGTVWGSGVIVDEKEGLILTCRHVVKGASYNQV
The following text describes a protein:
Function:
Acts as an activator of both RNA and protein methyltransferases.
Subcellular Localization:
Nucleus, nucleoplasm. Cytoplasm, perinuclear region.
Sequence:
MKLFVHNFMSSRFLKNVTVGYPLNLVVKQFVEKDIEFDRDNTIVMLDRIQYEALIVAAAAVNQSDRIPREKPEKWDELTDEQLRVFHHLLMNIDVIDGELICPETKTVFPIRDGIPNMLKVDAEK
The following text describes a protein:
Function:
Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglycosylase.
Subcellular Localization:
Secreted.
Sequence:
MHPLHLLTTALLTTCTSSLPSSLSHQRPKFDDSYTKAFQPFSWSSAKVRGANLGGWLVQEASIDTAFWNTYAPDAPDEWTLCTTLGLKCASVLEHRYATFITTSTIDTLASVGVNLLRIPTTYAAWINLPGSGLYSGNQKAYLRKITEYAITNYNMHIVIDVHSLPGGLNGLDIGEKKGNWGWFYNATAWNHSLEVVDAVVEFIFTSSSPRSFTLEPMNEPTDRNRDDDLTMAVFGTPAALSDRAAAYVMSFWKAVLERVRTLESGIGSGISGTIPVAFQSFKLPSYWGGNFTADSNVVFDVHNYYFEGRNTTSENLPTYMRSDAEEKSITGNGVPVYVGEWAIQAAYNNSFALREKNLNAGLSIWEEYMQGSAYWTAKFEGTDEVNGEGNKSDYWSFGGFIELGYLG
The following text describes a protein:
Function:
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers.
Subcellular Localization:
Membrane; Single-pass type IV membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type IV membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass type IV membrane protein. Endosome membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MDVFERTEQNFQHVCNSITRRIKQLPNYGGEKKKIAVREVENDIDEALKFISEMEKLAQNHPQRIKLQTKTKQYHSDIQKYKREVQLAQLQSSNQTNSNPWSNAPDDYQSQYDNQRQHLLQGSNMLDSTSDRLLRTHQISAQSEQIGQNILMDLGKQGEQIRGMRDKLHETDDQIKSARKIMTGIARRLATNKVILSIIILLLMGIIALIICLKWLR
The following text describes a protein:
Function:
Regulates renal phosphate excretion (By similarity). Regulates bone mineralization by osteoblasts and cartilage mineralization by chondrocytes (By similarity). Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage (By similarity). Increases dental pulp stem cell proliferation.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix. Secreted.
Domain:
The acidic serine aspartate-rich MEPE-associated (ASARM) motif is sufficient when phosphorylated to inhibit bone mineralization by osteoblasts and cartilage mineralization by chondrocytes by binding hydroxyapatite crystals during the mineralization stage. It can also inhibit dentin mineralization; The dentonin region is sufficient to promote dental pulp stem cell proliferation. It can also stimulate bone formation, osteoblast differentiation, and activate integrin signaling pathways.
Sequence:
MQAVSVGLFLFSMTWAAPKLNEDGSSGGNQGNIHLASVKPEPMVGKGTEGGRDAPLHLLDQNRQGATLLRNITQPVKSLVTGTEVQSDRNKEKKPQSVLSVIPTDVHNTNDYSEDTENQQRDLLLQNSPGQSKHTPRARRSTHYLTHLPQIRKILSDFEDSASPDLLVRGDNDVPPFSGDGQHFMHTPDRGGAVGSDPESSAGHPVSGSSNVEIVDPHTNGLGSNEIPGREGHIGGAYATRGKTAQGAGSADVSLVEGSNEITGSTKFRELPGKEGNRVDASSQNAHQGKVEFHYPQAPSKEKVKGGSREHTGKAGYNEIPKSSKGGASKDAEESKGNQVTLTESQRFPGKGKGQSSHSLGNEVKSEEDSSNSLSREGIAIAHRRTSHPTRNRGMSQRRGSWASRRPHPHRRVSTRQRDSSESSSSGSSSESSGD
The following text describes a protein:
Function:
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSITVVGASNWDMFTYVDTMPRVGETIKGNDFKVSFGGKAANQVVQAALLGSKCTIITKLGDDVSGVNTLKNFKDKNINCDYISIVKDVPSGCATIIVDKKGDNNIIIVGGANDKLSVEDIENAKSQIQNSSLLLCQLEVSLDVTLKALQVAKESKCKTILNLTPINDKPIVLEMLTFTDILIVNEIELYGIYKSTFNSSDAKEDESDINELIKRGEQLISKYNKIENIIVTLGGKGQLLLCKEPKDNCHIELKEKVKVVDTTGAGDSFIGSLAHYLTKGSPMKQSIELASKVASISVTRHGTQSSYPSLSEIN