lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression.
Miscellaneous:
MISCELLANEOUS: Present with 3280 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MLRSLHSAATLSNKRFYSLISHSNRKNIIKKLLRHPSFDPIRHHLPEDITTIDPYSLSQNVIESLNKLEVPKKDAAMVHNMMIENLSDLDYGVATIHSNNLRDLDLKPSLPAIKQIIRNNPGRVQSSWELFTQYKASMENVPDELMEVVLEKIIKFDKAEKVDGKKSLTYQDLVRCLYLINHFSSNYNLPSELVEPILIYIVDNGIPNVLGSVLKYKIPLSFFDKYVSEMTQYQICELYDFYSLDNIVADPLVLHKCLTVLGENEKIQQTEEEKEIISKLEEEIDIVKSQCHDNWSLEFPNWSVRKTATSFEELFLEIQKRNIDKKDFELAHKLLRLIGAFKGKVSLFFKLYDEYLLKFKNNEDDLMFEAFLTLCCQGYKSSNEKMLQYAEAFIKEDFDSKLESKIQSVLIVANAKANIDLSLKIYNSNISTAKREKDKYTDLAESDVLTESLILAFLSRDDADFARVIFDGALGEKLISGPTAAKKIKNLLAQYGEALETKTSKQVMQTKIEHYMESI
The following text describes a protein:
Function:
Dual specificity cAMP and cGMP phosphodiesterase with marked preference for cyclic AMP, which is activated by cAMP and cGMP. Likely functions as a cAMP-stimulated cAMP-phosphodiesterase which may play a role in regulating the cAMP relay response.
Subcellular Localization:
Cytoplasm, cytosol.
Domain:
The beta lactamase-like domain catalyzes the hydrolysis of cGMP.
Sequence:
MNSKYGDNIIDFLRYLEKFVKSLTKDNKIEEFKTFDIKSLLYPRNKDYFGNLSKFLLAVISARIGSNFINEDDIFEISELLKEFLGQELEHLPYLSYEELYVEIVEQVGEINGTVSEIIEAITVTIDFLDTFEKVSQTIDRSNEKQKLLAYLSAPVNQLDNSVSGVFNENDYTDIQRFFTELTNENNQSPDSNISILINDFQSLLNILESQQASSSSSKMIINDSPRTQQRNGTTEQQKKQQQQQYLQKNKEPFYSKDKIMQVSGPSYVFTPSDCNVSIQVGIPPDTLKRDQSICHFIVPHFLISKDVSLSEVEFPIFYNKFVQKGKTKVVIICTVEQKQRIETILCESIFGPAPEHIYTDEEITIPDYKIDLLTERLAIDPRANDEKLDSYVIFKTFDTFGVVDIDLPSASDPTKLINLRIRNTKGLISFHEDYHVVQKQLHLKLQEQQQDQQDKSSSSTTDKQMINTSGNRIILKNNTVSVIDSTIESQYVPVLPFGNDHEQVKKFKAPILGVTFLGVSHGLDFTHCSHTTGFIIWINGSGVVVDPPVGNTTYLQTNGIYGKTVEHIILTHCHADHDSGILQKIIERNKVTLYTTKTINESYMRKLKALTGLPEQSLKNYYTWVPVTIGNKIKILGAEFEFDYSFHVIPTIRFKLEIYNKKISYSADTFYDLQKFKQLKDQGVLSKKRIERLKSFVFDADMIIHESGVAPIHTPMANLLELPSEIRKKIRVVHCSSSVDTKGEIIRPKEGLENTEIIKVDRKYKGVAECIQIQTALNHCSVFSKLSPAEVQRVFFLCKKIWVKRNDVIIKKGSPSDMFYIILSGKVLVYENEYEPIKSTTSVGTVVTDTTTITTTVKTDAIKIPTIKLCAGETLGESALQLDKNIDASATVIAETDVCLLVWKTMDLRTEFHSNLNTFISKVHMDLSHINSCRDAIIRAFQHNITQHINKEEVDSIANGSKDVSFAHHQVIFNEGDTSDSMYIIKQGRVRIHSKKNKNIIRYLNVGDFFGETAYRRSNEDSNFLPTRSFTATAIDPTILLKLDIESIVNPRIQNIIEQKAKKNAEDNIRYHAYSPKIRTPRTPRKVYPIEGLSI
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
Sequence:
MPRRGYVPKREVLPDPKYQSKLVSKLINVIMEDGKKSISEKICYGAFEIIKEKTGQDPLKVFKQAIENIKPVLEVRPRRVGGATYQVPMEVRPNRRLSLALRWLTTYARQRKEKTMKERLAGEILDAYNNVGSSIKKREETHKMAEANRAFAHYRW
The following text describes a protein:
Function:
Part of the ESX-1 specialized secretion system, which delivers several virulence factors to host cells during infection, including the key virulence factors EsxA (ESAT-6) and EsxB (CFP-10). EccCb1 may link the cytosolic components of the system with the membrane components.
Miscellaneous:
MISCELLANEOUS: In ESX-1 cluster, the FtsK/SpoIIIE-like protein is split in two genes; MISCELLANEOUS: Was identified as a high-confidence drug target.
Subcellular Localization:
Cytoplasm. Note=Localizes at or near the cell pole in (on average) 1 discrete spot upon overexpression in M.smegmatis.
Domain:
The C-terminus (residues 252-747) interacts with EsxB, the whole protein is required for interaction with EccCa1.
Sequence:
MTAEPEVRTLREVVLDQLGTAESRAYKMWLPPLTNPVPLNELIARDRRQPLRFALGIMDEPRRHLQDVWGVDVSGAGGNIGIGGAPQTGKSTLLQTMVMSAAATHSPRNVQFYCIDLGGGGLIYLENLPHVGGVANRSEPDKVNRVVAEMQAVMRQRETTFKEHRVGSIGMYRQLRDDPSQPVASDPYGDVFLIIDGWPGFVGEFPDLEGQVQDLAAQGLAFGVHVIISTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDRITREIPANRPGRAVSMEKHHLMIGVPRFDGVHSADNLVEAITAGVTQIASQHTEQAPPVRVLPERIHLHELDPNPPGPESDYRTRWEIPIGLRETDLTPAHCHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGLLDAVPDTHLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSRSWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTCQMSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSSEFKVKRRPPGQAFLVSPDGKEVIQAPYIEPPEEVFAAPPSAG
The following text describes a protein:
Function:
Negatively regulates pheromone signaling during mating. Acts in a negative feedback loop that is essential for the mating process. This loop acts to down-regulate cellular sensitivity to pheromone. Activated by ste11.
Subcellular Localization:
Nucleus. Cytoplasm.
Domain:
The fungal-differentiation regulator (Fungal-DR) domain is only found in fungal regulator of G-protein signaling (RGS) proteins that regulate differentiation pathways. It is required for function.
Sequence:
MPALHNPSSPPPSYEAVTSYRNGNSIDSGDKRQQCSRLMKITSNGRPYSKDFLELFSTMVISTNFSRNRYRFSYVENSCTLLQLLSTLENLQLSQVNRIKSRCGSKVLKSTTKFTIPKTAAKCLCNTFLNARLLQIVNNPSARKFSNEKCLLQLTRKGYSVVSEFLQHNGHNSQAELYASKWNHSAPVIVSISRFSSTDQILKDSSFCEMLLVRMLGSVHEIGKSKNPLLVPVYSVSSPSPKDSLSKVTKYQMFGIDIAEWLMCNTMLLDWSEMETVASDLLIHSYIAYENNSETPLKFSYAKGVSYFLTGKGIATLGWTKNVSNNKLINKINEVEKGSTNKEILETILRKPNLQTYFFEFLKKNFCDENQRFYSEVCEFNDYFSHANETNDHEAIRESFAHACGIYNCFLSSNAPNAVNLPSDLYEKITNHMALAMEVEPLNEWLQLIHILLLEAQTAVLDLMAGDSLLKFLELNGGLGI
The following text describes a protein:
Function:
Involved in vacuolar transport and vacuole pH homeostasis. Also required for cytokinesis (By similarity).
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MQLEPAHLVYAAFWTFGLVNNVLYVVILTAAVDLVGPQTPKAVVLLADVLPSFLIKLAAPFFIHKIPYNRRITLLVGLSTVGMMSVSLASPLFLKLVGVVLASFSSGLGEVTFLQLTHFYDTRALNGWSSGTGGAGLVGSGLFMLLTTVLGVSVKTSLLVFAFFPLAFLGVYFYLLPPRDYNRVPGAFPVHSNDPETGIETQPITWEFVASGYETTMVRLKPLVMPYMLPLFLVYFSEYTINQGVAPTLLFPMEELPFSKFRDVYVTYGTLYQLGVFISRSSAPFVRIRRIMIPSVLQFANLVFCIAQSMSPILPNVWLVFILIFYEGLLGGAAYVNTFLLITEQADLAEREFALGSVGMSDSAGIVLAGLVSLWLEPGLCNYQVNDGRGWCTLE
The following text describes a protein:
Function:
Involved in the regulation of DNA damage repair.
Sequence:
MVKKRQADSRDHDCSTDSGNEDLHHRKGLGSPGQSDGATPTTASCQHIKKAVDAARLRRLLKSTGLLYECSQCQKLGKTAGSAAGAGASEGAVGPGGNPVTFEFDNTLWLCLKCGSQLCGRARHKHALEHYQTPHSDSHALAMNTRSFDIWCYECDMKICSNLRKNLLECVELVKKLAQKPPTSTVTPSTPTISYIEEKLKAALEHLTPIVPMTGGSFDDSSSRGSLAAAGGGGGVGSSRNRQVAIPMPPPEPSSGLSTSDSLTSVPGMAKRIDQYSATTNGNTGNKRLLTLETPRIENERLPRVRGLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGGTFTIKDKGDIELPMIKGTLSSWGGLTAALANALEELQAGGSVFTPRKLFDRLCVKCPQFTGGDQHDAHELLRQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYGNQAGDRILRPEQVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPVAVEKPQPPQRRKPSPELSLTSSSSSVTPSTGQPTINTKFTDGSVNFTASSPSFFLHAHEAASLGPSKSQVKKEKERQRKAKRAAKKRQKSSLNLNGNDSGNGNELAESVDQDDASLASLGAGDGQANDGLEQTNGQTEDSTTSSVTTSEHSDADVEDNLVEDTAAPSTNNVPSSTASLTAPSKTYMDSNGNAQPPGEKRDDTPEHMDKDSLEEDENDSGIATSPAPTATNSSTSTSATGNNNSVAGSGLSGSSGALEDPLAPASLVTAGLSEKGASVIRQVSVGAEQGASNGTEDADGEAKAIEQPEKTPSQAQAMAQAQARTKRVRTQSYSDWSTTIAPRYQCEDGECSVQSCLNNFTAVELMTGQNKVGCDSCTQRINGSDPKAKSVNTNATKQLLVSSPPAVLILHLKRFQLGPRCIFRKLTRPVSYPNLLDIAAFCGSKVKNLPNIDRKQKKLLYALYGVVEHSGGMYGGHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQDDDQLKKLEELLAKEKAREQHLKVLDDSDDFSNSSSNSSTSDESQTPATPLEEQQTQQAQQPQQPQQLEEAANVRAPPGKWYYVSDSRVQEVSEDTALKAQAYLLFYERIY
The following text describes a protein:
Function:
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase CheA; they are both necessary for efficient chemotaxis.
Subcellular Localization:
Cytoplasm.
Sequence:
MTAEIKTGEKMIVFMVNGKEYAISVTQVKSIEKWQKPTRVPGVEPYICGVINLRGVVTPVIDLRKRLNLPEYEITDETRIIIIAYRDIEVGWIVDEANDVITVHESEIESAPEGVQKDTDVSIEQIVKQENRLLNIIDANAVLDKESSQSAVPDQA
The following text describes a protein:
Function:
Global transcriptional regulator that regulates virulence factors production by activating or repressing the expression of a large set of genes in diffusible signal factor (DSF) pathway.
Subcellular Localization:
Cytoplasm.
Domain:
Binding of c-di-GMP appears to trigger the active Clp conformation into an open form or inactive state, hence abolishing its DNA-binding ability.
Sequence:
MSSANTTVVTTTVRNATPSLALDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYFGSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQLFQTSLSPDAPKILYAIGVQLSKRLLDTTRKASRLAFLDVTDRIVRTLHDLSKEPEAMSHPQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR
The following text describes a protein:
Function:
Involved in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis (By similarity).
Sequence:
MGAAKNIWALANAEDAANDAEQIPYSSFVVDTSLPLPLMIPRIIELCKDLFKNWGELDDSLFSVERVSGGITNLLLKVSVKEDTNKEVSVTVRLYGPNTEYVINREREILAIKYLSAAGFGAKLLGGFGNGMVQSFINARTLEPSDMREPKIAAQIARELGKFHKVDIPGSKEPQLWVDILKFYEKASTLTFEEPDKQKLFETISFEELHKEIIELREFTGLLNAPVVFAHNDLLSGNFMLNDEEEKLYLIDFEYGSYNYRGFDIGNHFNEYAGYDCDYSLYPSKEEQYHFIKHYLQPDKPDEVSIAEVESVFVETDAYKLASHLYWAIWAIIQARMSPIEFEYLGYFFLRYNEYKKQKPLTFSLVTSHLSASL
The following text describes a protein:
Function:
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
Subcellular Localization:
Nucleus.
Sequence:
MAPPPFSSSPWLQLNRPIQCADNETLVAYFLSKRKELVDADKISDNLEATLSVAHRNITTCKTPIQTIQDLSKIKGVGLWILKRMEEFFSNTTTEKLPQKGKRAKGSKPYLPKKKSVAYALLITLYRELMNGRDYMKKQELIDAAGGSGLCEASIVRDKGLGKPGQPSSKDWYTGWNAMTTLINKGLVVRKSNPAKYMLTDEGKKVALDCIKRSGLTDFIEGDDTNNRSTGVGCAQTASVSDLNHTTISQNKKTYDIVNLSDSEMNIPDVSSDSVELLEDGSAYLSEGNFATLRKDKKVLKYSSGKDTAISGNFVSMNSLLQTHTSLSDRLVGLSSPNDDDLVTASKTLSMPAHLNEQVFNIGSAYSFEGKDKNILKCSGGLSGRDSAIPGNSMARNCLIQPCTSLSDRLVSASSPNVDDLQSVSKTLPMPPRLNGDRFNDVYDVILLLDNRENFCAGAGRGNVAEMLRSRFKILVEIRRLPVGDGTWIVRHRHHKKEYILDFIVERKRVDDLKGSLIDNRYKDQKLRLLRCGLQKLIYLVEGDPNQCEGTEAIKTACFTTEIVDGFDVIRTAGLTETIGKYGHLTRAITQFYSAQFHSNSNKNPKICPTYVEFIKRCHDLNKMTISKLFSVQLMQVPRVVEDIALAVVDLYPTLISLYNAYKVLEGDVCAQEQMLMKQSNLISKSASKNIYNFVWISD
The following text describes a protein:
Function:
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MSAEEETVPTNVEETVTAPASEKKPAAKGGKAKKTKEVKAAAAPKKKPAAKSPRKRASSSHPTYEEMIKDAITTLKERTGSSQYAIQKFIEEKQKSLPPTFRKLLLVNLKRLVASGKLVKVKGSFKLPSAKSTAVSAAPKPAPVKKATVSTKPKAKVAKPAAKGTKKTKAVVAAVKPKAKVAAKAKPKTKTKTVAAVSKTKAVAAKPKAKERPAKAARTSSRTSPGKKAAAPAKKAAAAVTKKAKAKAPAAKSVKAKSPAKRASTRKVKK
The following text describes a protein:
Function:
Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex. May be involved in lateral roots and nodules formation.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MASEKVETVIAGNYVEMEREEGSSKSTKSKFSNFLWHGGSVYDAWFSCASNQVAQVLLTLPYSFSQLGLLSGILFQLLYGLMGSWTAYLISVLYVEYRTRKEREKVDFRNHVIQWFEVLDGLLGKYWRNIGLLFNCTFLVFGSVIQLIACASNIYYINDNLDKRTWTYIFGACCATTVFVPSFHNYRIWSFLGLMMTSYTAWYMTIASLIHGQIEEVKHSGPTTMVLYFTGATNILYTFGGHAVTVEIMHAMWKPQKFKLIYLIATLYVLTLTLPSASAVYWAFGDLLLTHSNALSLLPKNGYRDTAIILMLIHQFITFGFACTPLYFVWEKFIRVHDTKSVLKRALARLPVVIPIWFLAIIFPFFGPINSTVGSLLVSFTVYIIPSLAHMITFSSASARENAVERPPPFLGGWVGLYCVNIFVMVWVFIVGFGFGGWASMLNFIRQIDSFGLFTKCYQCPPHKA
The following text describes a protein:
Function:
Key component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates the extraction of incompletely synthesized nascent chains from stalled ribosomes as well as their ubiquitin-mediated proteasomal degradation. Thereby, frees 60S subunit ribosomes from the stalled translation complex and prevents the accumulation of nascent polypeptide chains that are potentially toxic for the cell. Within the RQC complex, NEMF specifically binds stalled 60S ribosomal subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety and promotes the recruitment of LTN1 to stalled 60S subunits (By similarity). Following binding to stalled 60S ribosomal subunits, NEMF mediates CAT tailing by recruiting alanine-charged tRNA to the A-site and directing the elongation of stalled nascent chains independently of mRNA or 40S subunits, leading to non-templated C-terminal alanine extensions (CAT tails). Mainly recruits alanine-charged tRNAs, but can also other amino acid-charged tRNAs (By similarity). CAT tailing is required to promote ubiquitination of stalled nascent chains by different E3 ubiquitin-protein ligases (By similarity). In the canonical RQC pathway (RQC-L), CAT tailing facilitates LTN1-dependent ubiquitination by exposing lysine residues that would otherwise remain buried in the ribosomal exit tunnel (By similarity). In the alternative RQC pathway (RQC-C) CAT tailing creates an C-degron mainly composed of alanine that is recognized by the CRL2(KLHDC10) and RCHY1/PIRH2 E3 ligases, leading to ubiquitination and degradation of stalled nascent chains (By similarity). NEMF may also indirectly play a role in nuclear export (By similarity).
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: Due to intron retention.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Sequence:
MKSRFSTVDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRGNIVLTDYEYLILNILRFRTDEADDVKFAVRERYPIDHARAAEPLLTLERLTEVIAAAPKGEVLKRVLNPLLPYGPALIEHCLIESGFSGNAKVDEKLESKDIEKILVCVQRAEDYLRKTSNFNGKGYIIQKREAKPSLDADKPAEDILTYEEFHPFLFSQHLQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRAIQVVRSALANQIDWTEIGVIVKEAQAQGDPVACAIKELKLQTNHVTMLLRNPYLLSEEEDGDGDASIENSDAEAPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQRTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHRGERKVRVQDEDMETLTSCTSELMAEEMEQLEGGDSSEEETEELHGMPGDVELMTQVDQEDIAVHSGRDELSSEDGEAKAVTKDQEPIGEMKEEEEDTFEYPDTTIDLSHLQSQRPLQKLAPREESLNSNDSKSQGRRHLSAKERREMKKKKLPCESGDLEVIEEKDKERESAVHTEAYQNTSKNVAAGQPMKRGQKSKMKKMKEKYKDQDDEDRELIMKLLASAGSNKEEKGKKGKKGKPKDEPVKKPPQKPRGGQRVLDVVKEPPSLQVLAHDLQDLAVDDPHDDKEEHDLDQQGNEENLFDSLTGQPHPEDVLMFAIPICAPYTIMTNYKYKVKLTPGVQKKGKAAKTALNSFMHSKEATAREKDLFRSVKDTDLSRNIPGKVKVSAPNLLHVKRK
The following text describes a protein:
Function:
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
Subcellular Localization:
Nucleus.
Sequence:
MASSSSAASLFATECLLYSTASSSTLVGSMGLTTVAAPSSTSALFTFKGVSDPAFHSVTVIPTSPNPAISGTGGLIFQLESNKAALNIFSWQRDHLLQRIILPSKLSCIACSPNGDLVAGGSFDGRILLWQIATGDLLASFDAHYRSVTVLKWTCDGAGLLTGSEDARILVWSLAGLLAPHDQTSSSITSSEHNPAPYCTLADHNLAITDLDISSGRFPHQAMVLSSSSDASVKLWDLRTRSLLSTFVFEQPIHRVVLDCTERFFFAATAPTSSDNLVYRIDLFRKRDASSRMVETKQATTGSQFDFVTDELRGASSVEAHGFGSAAGPTTERIPSARDVAHRAESNGSSIISIREPISSMCLSTNSTSLLVGSVAGNLFVIDVSNSQVVRTVSLLGNAKVSAISDKNAVTNLMVLPKPRDLLGHWETLSSSGTGSSMSGSGGVGGAGAPVGIPVRPIASSFGHHVLASEEDRLSKPYLTRISGNKTTLAFDEHNVDSFIDPEWDSHLVSSELLGRSTSALLSPSQTQSGAPPSTSAIHAQAALEAERLQRENKLLRSQLHQAKAINDEMWSRLVQDRLSVNQVDSE
The following text describes a protein:
Function:
Acts as a scaffold, mediating interaction of ROPs with different proteins. Required for primary and adventitious root maintenance, but not for their formation. Promotes the stabilization of ARAC11 on the plasma membrane of the pollen tube initiation site but not the activation of ARAC11. Regulates directionality of polar auxin transport, and is required for the formation of a stable auxin maximum and tip localized auxin gradient during embryogenesis, organogenesis, and meristem activity. Involved in exocytosis and in the recycling of PIN proteins back to the plasma membrane.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Nucleus. Note=The localization of the ICR1-ROP complexes at the plasma membrane depend on the lipid modifications of the ROPs. Localized in the nuclei in mature pollen, then shifts to the site of germination and stays at the apical cortex of growing pollen tubes.
Domain:
Interactions with ROPs and SEC3A require an intact C-terminal coiled-coil domain.
Sequence:
MPRPRVSELSQRQAPRLRSSSSTSDSNHSNRLITTDQSFKPGVDRKSPRSGGPNSDPLGQKKLGGRISDLESQLGQAQEELRLLKEQLANAEAVKKQAQDELHKKSKKPNPLARVEESATEAERIDRDEIPGDVQKETDVFEVPVEKIAVEEEELRSGNDEAEKLVAKEDEIKMLKARLYDMEKEHESLGKENESLKNQLSDSASEISNVKANEDEMVSKVSRIGEELEESRAKTAHLKEKLESMEEAKDALEAEMKKLRVQTEQWRKAADAAAAVLSGEFEMNGRDRSGSTEKYYAGGFFDPSAGFMDPPGMADDYDDGLGSGKRKSSGMKMFGELWRKKGQK
The following text describes a protein:
Function:
The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of bacteria.
Subcellular Localization:
Secreted, cell wall, S-layer.
Sequence:
SATVELYSNLAAKGLAVEFTSTSLKAALLNILSVDGVPATTAK
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MVRVRRTSAPLLAAAVVAAVAVACSLGSGAYAAAEQEAVGAGAGAGVDDLWLRQPPITRGLSLDFYKRSCPRAASIVRHFVRDAVRKDVGLAAGLLRLHFHDCFVQGCDASVLLDGSATGPGEQQAPDTPPVGLQGHQRHPRPAGARVPRRRGVLLRHPGARRARLRGGLRRSGVPRAPRAPRQPAVRHAAGRAVRPPRADVHRAVPPQRGRLARPRRHRPRRALRRAHHAARALHLLRGPPLPAPRPDHELGLPRQAEADVPTDRRTPLDVRTPDVFDNKYCVNLVNREGLFVSDQDLFTNANTRPIASSSASPAASGTSSTSSACPW
The following text describes a protein:
Function:
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MVRLKHRYILVEILWKDWQNPSIHQLPVAEEDIYGSVRNAIQYLHGEFGVGVTRFHLTIKFFNPYTRVFLLRTRRGAHTLTLSALPFVTKIKDDAATLRVLKLAGTIRSCLKFLKKYDCAVMLDVLNRAVSAEAKRQAKEKIAEVYASMETTKGGIRPM
The following text describes a protein:
Function:
Required for post-transcriptional gene silencing and natural virus resistance. May bind nucleic acids and is essential for the biogenesis of trans-acting siRNAs but is not required for silencing induced by IR-PTGS. Involved in the juvenile-to-adult transition regulation. In case of begomoviruses infection, it is targeted by the viral protein V2 leading to suppression of post-transcriptional gene silencing. Involved in the mechanisms necessary for quick response to heat and subsequent heritable transgenerational memory of heat acclimation (global warming) such as early flowering and attenuated immunity; this process includes epigenetic regulation as well as post-transcriptional gene silencing (PTGS). In response to heat, HSFA2 is activated and promotes the expression of REF6 which in turn derepresses HSFA2, thus establishing an inheritable feedback loop able to trigger SGIP1 and subsequent SGIP1-mediated SGS3 degradation; this prevents the biosynthesis of trans-acting siRNA (tasiRNA) and leads to the release of HTT5, which drives early flowering but attenuates immunity.
Subcellular Localization:
Cytoplasm, perinuclear region. Cytoplasmic granule. Note=Accumulates in inclusion bodies in the cell periphery. May interact with the ER network from the perinuclear region out to the cell periphery (By similarity). Co-localizes with SGIP1 in cytoplasmic granules.
Sequence:
MSSRAGPMSKEKNVQGGYRPEVEQLVQGLAGTRLASSQDDGGEWEVISKKNKNKPGNTSGKTWVSQNSNPPRAWGGQQQGRGSNVSGRGNNVSGRGNGNGRGIQANISGRGRALSRKYDNNFVAPPPVSRPPLEGGWNWQARGGSAQHTAVQEFPDVEDDVDNASEEENDSDALDDSDDDLASDDYDSDVSQKSHGSRKQNKWFKKFFGSLDSLSIEQINEPQRQWHCPACQNGPGAIDWYNLHPLLAHARTKGARRVKLHRELAEVLEKDLQMRGASVIPCGEIYGQWKGLGEDEKDYEIVWPPMVIIMNTRLDKDDNDKWLGMGNQELLEYFDKYEALRARHSYGPQGHRGMSVLMFESSATGYLEAERLHRELAEMGLDRIAWGQKRSMFSGGVRQLYGFLATKQDLDIFNQHSQGKTRLKFELKSYQEMVVKELRQISEDNQQLNYFKNKLSKQNKHAKVLEESLEIMSEKLRRTAEDNRIVRQRTKMQHEQNREEMDAHDRFFMDSIKQIHERRDAKEENFEMLQQQERAKVVGQQQQNINPSSNDDCRKRAEEVSSFIEFQEKEMEEFVEEREMLIKDQEKKMEDMKKRHHEEIFDLEKEFDEALEQLMYKHGLHNEDD
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MPLNPFSRSANNPSRNERRDPHRGLSDLLNSAHLQHGARWSNNVKASILRQLWQTVWQDPQWIQYFVPEGTHVPVYDNLWEWLVDTPDGPSKPWTLSEKQAQIEEERKSEGKKPIWTRRKGQICGKVMQRHDRTYTCKTCAITPSVSLCVDCFRASDHQGHEVLFGQSFSFSASCDCGDPTAWKDDSHLGCTHHPRLPPGSPPPSFPDKFDLPDSLVISLQKTIAMCIEFIIHTIEHSHLPSEYGLLPKTETEMHSSDGPTGEPKDKRGTGPWAVVLWQDDRHVLKELARQVRDGLGVKWEVAEQWVREAITVGRKIILVSPNPVIAFHAANMLQQIDAPVTLRPAADVFREEIVATLMDWLYDIQGSLIGGDDRLPKRLIFNALFEKRMLPPGGHGTPLANDLSDLANGKMLGATQVVKRMDWLLQLDSRLWKKAKWQLRQIYCSVFLSDVEARKAFASSFAFNYPRLAEHFLFQDREFDANIIFSSAYLVFTNGPATAHASAHANLLTNVVQVAHAWYTGQVVTNEGCDRLVIPPVAFDPNDSTSQGRLDLDAHAFSGKKGLAILGHLRSMFRHEEMKKLVVKQNQLFGRVLGFINMFVGIQPQRRERGGHIEYEVEWLKSFTVLGDLARICRDLGEVFSVASADALLQNMSLVANRIFCDMFLISNTLDKDRYTPLTEYTINDVLVLGTSVTVIKQDVTTIEAFSFHHYLNLLFAGMLKCMRTGIPWENGKVNGMDFNRIVEKFVLGSNDEQAMERMKLMLIEWPLQKHVVFAQLRANMWKKNGSALRLQHHHYCDVSVRESTIDQEFFLLQFGLCILDPFTFIVALIDRFGLTKMFQGNVEKALLWYGEDPDPRQIINLMEDLLLLIIHLVSYPAIINGWDRKTITRKLIIHLLAVQPMTYSELFKKLPERSQEISCTPILAEVANFRQPTETTSGQYSLKDEVYDEVDVHWRYYTRNDQRSVMDKLVARAKKNKPSNEEPLILPRPLEFPSTDSPFSGVSHFLHTHVVADLVHWALAHCMHIATPDKWAEIVQQAYPQEYSNTPLIPSWDFVLDYTLHLAMIALGVAPQEFAQQSVFLKGVEGSNSTFQNLWVMQSDPAFKAFKPRVDYVLDTIVANLPPHYTADYRAHKESENMLALSSLAKPDPKAAAAARQKAIMAEFAKQQQDFVAMMEDMDDEDEDILVDEQKEEEESYGNCIVCQEEVTAKNAGGMLTLLQPSRQLRDVVNTRDWFEESLLAPTSMDRPGRYQRYSYDPKHPEPVGTQGYPCTNLRFGIHMSACGHYMHDTCMNSHFETTKIRHTQQVQRHHPENAVRLEYMCPLCKSLGNVLIPVEPSHIAKKPAVSAKKDEDKPPSLSVMIRRVSSEGLLRVADSQRIWEHHVETGEVVPWFSDCVFSLHSLDHNHRRGAMRVISKMVDRMGGLVRPLSEQSQRIRGKKTHMYLPDDMVAYTVSMAEITQRGLKTNSAEALTVAEQINETTLKLVGKLIGLLQLELDLYFGPTFDRTSLRVGIFARFLPDWYRSSTLPSPLLIRQPLGMVIECAAIAPDLLQAVIVMAYYAELTRCMLALSLSVKRCLGPRTRPSPRTQPPEDPSLTDALTVFSGFRPVMQSILRHAGPFADTDGVLALLTDDMLSKLLYSYTLPFLRRCAIIYYSVTGTYPITQPSALSTFTPATSEYNRLLTILGIPRPTETLANSSSTETPIVARWITQWALHGRVMPVLEFPGTYELARLPEKWEELVLAYSDRKCGKCKTKPSYPAICLFCGTMVCLAGDCCAEGEQGECNLHMRECGAVVGMFADIKRWNLLYLYAGSGSFGPMPYLDTHGELDISMRRGHRQIMHVGRMDELRRGTWLMHNIPHITARRLELTIDHGGWGCL
The following text describes a protein:
Function:
Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine.
Miscellaneous:
MISCELLANEOUS: Present with 8430 molecules/cell in log phase SD medium; MISCELLANEOUS: ct(6)A is involved in promoting decoding efficiency. It is an unstable modification that can be easily hydrolyzed and converted to t(6)A during nucleoside preparation by conventional methods.
Subcellular Localization:
Mitochondrion outer membrane; Multi-pass membrane protein.
Sequence:
MANNTWKLIATTALISVFSTQLAKSVWKEYKLSCAANKNKTVSRPRQYDDHLFREQLARNYAFLGEEGMRKIKEQYIVIVGAGEVGSWVCTMLIRSGCQKIMIIDPENISIDSLNTHCCAVLSDIGKPKVQCLKEHLSKIAPWSEIKARAKAWTKENSHDLIFADGESPTFIVDCLDNLESKVDLLEYAHHNKIDVISSMGVATKSDPTRVSINDISMTEFDPISRCVRRKLRKRGIATGISVVFSNEMLDPRRDDILSPIDCEHRAINAVRDEALRHLPELGTMPGIFGLSIATWILTKVSGYPMKENEVKNRLKFYDSILETFQKQMARLNENKERSSLLGLEEVGYIVEEMFRGKSPISGYSTKLALTKWEANKEISLTNVVLMTKEEQEIHEKRILLDGEKLTAVYSEEVLDFIERLFKEEEYYS
The following text describes a protein:
Function:
E3 UFM1-protein ligase that mediates ufmylation of target proteins.
Sequence:
MEELEILRKKLYSIQRQDNTQKLSERNCIEIIVKMIDLKMIDIIHSLDGKEYITPKQLENEIKDEILKCGGRVVVCDLQSILSIDIIHIEEALEKLKKRDKSIQIYQGEIMTRYYLDSILQEIQEQLQEVGKLHINDLSNRFSIGVDFLINLIEQNLKKFNRSLNNSTNNNNNNNNILLKNIIFDNQEVLYTQSHINRHYHKVIGLFSSITQPILINNVIKQHQNHYQLNERLVRQQLQELIENKRINGFIQGKASNAEFIPTIFSQSRLKWIDSFYHQNQFITFDSVSKLQINEPQSFLKNTFTDGLLLHSCFIHKSLIDKIDDNIIEIIENSNWLDLIPLLPPLTDKDISMIVSNCPNMKTNNAILLGNSFIISKSFVDRCFTLLQKTIQERMEKQQLILENIASSNIKKQQQSKSEIIDQKIETTTTTTTTTQPSKKKDNLINSDDDDNQDNNKKSSKGKNKKSKQQQSSIQKLINDSEDDYKVYNKKQENNNNNKKVDHLKEINQLLSKWYENMEEELVESLSQYLRPLVNQSWESMVKEAKEKLENETQKQRKQQLQQLNSQFFSLYNSFLLFRKGLQSLNDADDDNGKTIIALEKHLLKTVGINITNLLIEINANYHMLDKTTFETPSERSLILSQFPPQLSKSFEKLIQSLNKSTLNDFIDSLENVCSQSQIKLKSLDKKLEKQLLIENQNELEEQFLNEIDVGNQFQIIVNLMYIRYKNNYIFSPPRLIGKLVSTLVMDTSIDKEIITRLTKLHQEIVKLITNNKLSNQDNDNDSTELNDHIKFFKDLILN