lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MDKAFLISLPLLTMTAAETNPNCSIQDHNNVYIGELVKKLKTAASLPDVNVKKSKKLKIAALLTTDRKKAAFLQALSDLHLSCKRGDDDRALQTLIGLASKAAALAHMAGTSAALTKLATLKKKTDTNAFTTGTNSAQRKRIAVDGAKTGINTGKCTIHSYINAEAPAGADKALSNWQHSLKVVKPDTTAATQGATQAMVCETTNGQCSSSSSGNTAGISSGTLYKTDPAAKQQTGKVKPSATTKEWVFHSDKIAHQAAQLDTELSDALTTYATTTDSCEPYNKLDNNNFILRVYKIAKGDDTATEIPQAERNNIKNIVESSYGKDPTTYEETIWKGVKATPLTKSNSGRPSDTKLDSITTLNDLQQIEAFIEASAAIKQNERSSASTSECKAQIETASACKGKEKKNCNSNCEWEGTEDKGTCKPKNEEEGVKVENDGKTNTNTTGGNSFVINKAPLLLAFLHMGQKLCQTFFLR
The following text describes a protein:
Function:
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.
Subcellular Localization:
Nucleus.
Sequence:
MALCQTSVLKVYHAVIEDVITNVRDAFLDEGVDEQVLQEMKQVWRNKLLASKAVELSPDSGDGSHPPPIVANNPKSHKAANAKAKKAAAATAVTSHQHIGGNSSMSSLVGLKSSAGMAAGSGIRNGLVPIKQEVNSQNPPPLHPTSAASMMQKQQQAASSGQGSIPIVATLDPNRIMPVNITLPSPAGSASSESRVLTIQVPASALQENQLTQILTAHLISSIMSLPTTLASSVLQQHVNAALSSANHQKTLAAAKQLDGALDSSDEDESEESDDNIDNDDDDDLDKDDDEDAEHEDAAEEEPLNSEDDVTDEDSAEMFDTDNVIVCQYDKITRSRNKWKFYLKDGIMNMRGKDYVFQKSNGDAEW
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MIFYDKLKPADVLVIGSADGRVIEAIEYIADLHKQHGFKFAICLGNLFSHKRTTSADVVKLKNEKVKVPIPVYFGVGTAGLPESIISHMAMYGPEVAPNLFCMGICGFMKTFYKFTIAQLGGSYNEEKYYQPPEKFEQSLNEKCFHRSDVQKLSKRCDILFSSEWPEDVQENSTLPERKLPKGCMPLAALAANCMPQYFFVPGPVYYEREPYKNSAAINVNTGTVTHFVALAPFKNSKNEKFSYAFTLYPLTTEYMQPAPPNCTASPFEHRPIPLKRASEDQIIPQQTNKFHKSKSSTALFKSKKDSSSSLNKMHKSESHSALNNLHKSESGTSLNNRRSKVGPGSCFFCLSNPNVALHLIVAIGNEAYMALPKGPLTTTASNTPALASSGHVLIIPIAHASALSTLSDTSYEKTLNEMNRFRKAVTDMYNACDSDALVYEISRANGVHLHWQMIPIPKISSHRIESVFLEMAKEAGYDFEERDVEPHELNYFRVFLPSGKILIHRLQLRERFDLQFGRRAAAKILGLEDRVDWRKCVQTEDEEKAESEAFKMCFKPYDFT
The following text describes a protein:
Function:
Required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MALIEDLNHFINYFPLVLRLFFLVVFGLYSFTLILHLLVINRVDVFSLLHTPLPVNRSQQANAPLWQLSFSLSILGTLLFVIAESLYLISGSDELAYVPVFIFGVIVFMPVHKFWFFQRKVFTRQCLRILGGSYRPDYKFPDVIFSDLLTSYSRVIADLWLAGAILIYVTDSPNNSHRKQYENEVIMSMIAAYPYAIRFRQCLIERSSADNSSDKFWSTLNSIKYFTAFPAIFLGIFAKKRFSFLWFLWNTSSAINSTYSFWWDVSMDWSLPFFKQPLSIQNWKFGVRRLFPTFTFAVVSAIDFVLRMAWVVRVLPEHQSAFFTTDFGIFIMQFLEVFRRCVWVFFRIEAEASKSLAYVNISDRSDIPTIHPD
The following text describes a protein:
Function:
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins.
Sequence:
MKRRGLSLEKDYSVFEFNDEAVEQQSIKVMGKYASHHNPKVDESGVTKYQFLECFSKTNNAPQAGVHDGCCLDFMPTGISEKSGPSVVYQNHELYTVNKSGLNGTCEEASLGLKDILVTSSQDINEAARHTIQGNYESGVFMSRADSLPSEFLGLEVPCKYPNQVKDTPLQAEENLVDVASDGEGSLMKSSVSTSDSNLSGDEGVMEPSTSDHCSSGYCDKGTECSEVAFTSDFVFCGKRHYQDPRLTFFSECIKLEVPFANGNDATLSWKWGLLDIFSIEYNWVESVSATWLRLHLSPTAMTDGESVWDASGGVVKLIFAVNDPNWLEKVHMITFLSDRYKDICNAPYDSDCNSEKINDDDSMGIQAEMSNNPYLTRCNEPFEDLVYPKGDPDAVSIGKRDVELLQPEVFVNDTIIDFYIKYLQCKLEEHDKNRFHFFNSFFFRKLADLDKNPGCAFESKAAFQRVRKWTRKVNMFKKDYIFIPVNFNYHWSLMVICHPGEVVKSEDDNDHKVPCVLHLDSIKGSHKDLKDLVQGYLWEEWKERHAEEKESCENALVNFSNMRFIPLELPQQENSFDCGLFLLHYVELFLRDVPTNFSPFKITKYSNFLTKDWFPPVEAFSKRFHLQKLIYDLHDDHIRTIPPSHSSSDDESTGIGDTEVGDQIIDFVTEECAGANLCLGNSFHSTVEANESSNSNLLISLPVHDGVVGDEACLHDNAGGTICADFLMHDAPCATSPDGQTRPFQDASSPPLLDCALNRLKAYIVDGNEPMEPELALSPTQKPVHIARPETSIACTEDVISGSKESLQIQASPPHNNHFPQPSKSACSASSSSCGSQAVWPPHQHNVDPTTQDHERAATVPAPTSTEDHDCVPLSPVSVSSERARLSVTEASFLEDDNNNHTVAESKESGDSFFSCPDNLPAPPIRDPELPENGGLLPGNIDSGKDLTGNDDCMEITDEVLSEEQMKMTSPKRMKLGLDVGPERQAFTETG
The following text describes a protein:
Function:
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.
Subcellular Localization:
Nucleus.
Sequence:
MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPRPRIYPVAPAMSVSELSYRVPPATPGCDPGGLGEVPSVHSRPAYFRPPGLGHPIFSPSHLASKTPPPLYLATDGRRPDLPPGLVGARGGLGTSRSLYSGLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQGPLQPSPWPPTRDAVDPARPVARSLCKEGPPSRGASPPTPPVSIKSERLSPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASLHRLTPDSWPR
The following text describes a protein:
Function:
Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
Subcellular Localization:
Cytoplasm.
Sequence:
MKFITQQEDLYKSLQFVKSAVATKTTIPILTYVYMKAENDTLYLQGNNLEIGLALSMPVIVEEPGEVCLPASLFIDVIGKLPEVTLEIHVNERNRAVIHAGYSDIEIQGESTEEFPKVEIGNIGEYHASFDRILFAKAIKQTIFAAAEDEIKQVLTGVLFEGKEGKLNMVAVDGHRLALKTLEIEKDFAPIIVPSKSLKEWQKIITKAMDDRVNMAALDNQVVFNCGEIYFISRLLQGQFPAYDKIIPTDFTASFKANRKDFLDVLGRMEVFAEIDQTNTVKISLSSEEVVISTLPSERGFAKEVLPAEVEIDGNLEIGFNVEYLMDPLDNADWDEVVMRFTSDLGPALITSPEDENYTYILMPVRL
The following text describes a protein:
Function:
May be part of a signal-dependent gene regulation cascade that is relevant to swimming motility. May be involved in the transcription regulation of target genes.
Sequence:
MVTERSARESPEQRAAEQVVLVVDDDEDLADTCRYWLDGERFAVETAYGGEEALHRLDDTVDVVLLDRRMPNVTGDDVLEEIRERGLDCRVAMMTAVEPDTDIVEMPFDAYLVKPVSESEVKETVEELLVRSGFESGVREYFALESTEAALDSRDVEELREPEALSDLRSRLEAVRAEHEAAIRNREAQLDRLNRTNELLRDVDRALIDARTRDEIEQTVCDVVADAHEAAVVLRRTAAGTLRCTAAAGHGLDPAGVDLDFVDEAFGVDGAAEDGFVFEDIPGAHRAAVLGDDADDLDAVSALCVSIDYRETMYGALVVYDETDGFDDESAGLFSDLGATVGNGINATQSKRLLNGDSVVELEFQVGRDAGVLARLSAALDCQLSLDGVTRLDDGLACFISVAGASGCDAVAAAIDAVDVSQARVVADGDEESVVELRTDAEAVLSTAIDHGASVERLTLSEGSGTLTLHVAADADHGALVEAVTTAAAGVSVVAKREVERSVQSADSFRRALDSKLTDRQRTVLETSLVSGYFEWPRGSTAEEVADSLGISPPTLHEHLRTAERKLIETYFDELNQAPADD
The following text describes a protein:
Function:
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MAPTITTTTTTMAPTYTSIPIPTGDVISRSIHNLTSAISRHRPWSELVFSGAFCFPERFSSLPLRSRSNFRYFSVNYSLIIGTCAAFSLVTASPVALVVVGTIIALWLLLHFFREDPLLLWGFQVGDRMVVCFLVLASVWALWFTSSAVSLAVGVSVGLLLCTVHSLIRNSDELFLEEDDAITGGLIGSNRR
The following text describes a protein:
Function:
Lipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress response (By similarity). At the lipid-aqueous interface, hydrolyzes the ester bond of fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) (By similarity). Specifically targets phospholipids with a short-chain fatty acyl group at sn-2 position. Can hydrolyze phospholipids with long fatty acyl chains, only if they carry oxidized functional groups (By similarity). Hydrolyzes and inactivates platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), a potent pro-inflammatory signaling lipid that acts through PTAFR on various innate immune cells (By similarity). Hydrolyzes oxidatively truncated phospholipids carrying an aldehyde group at omega position, preventing their accumulation in low-density lipoprotein (LDL) particles and uncontrolled pro-inflammatory effects (By similarity). As part of high-density lipoprotein (HDL) particles, can hydrolyze phospholipids having long-chain fatty acyl hydroperoxides at sn-2 position and protect against potential accumulation of these oxylipins in the vascular wall (By similarity). Catalyzes the release from membrane phospholipids of F2-isoprostanes, lipid biomarkers of cellular oxidative damage (By similarity).
Subcellular Localization:
Secreted, extracellular space. Note=Associates with both LDL and HDL particles in plasma. Mainly associates with pro-inflammatory electronegative LDL particles.
Sequence:
MLPSKLHALFCLCTCLALVYPFDWQDLNPVAYIESPAWVSKIQALMAAANIGQSKIPRGNGSYSVGCTDLMFDYTNKGTFLRLYYPSQDDDHSDTLWIPNKEYFLGLSKFLGTHWLVGKIMGLFFGSMTTPAAWNAHLRTGEKYPLIIFSHGLGAFRTIYSAIGIDLASHGFIVAAVEHRDGSASSTYYFKDQSAVEIGNKSWLYLRTLKRGEEEFPLRNEQLRQRAKECSQALSLILDIDHGRPVTNVLDLEFDVEQLKDSIDRDKIAIIGHSFGGATVIQTLSEDQRFRCGIALDAWMFPVGDEVYSRIPQPLFFINSERFQYPSNIIRMKKCFLPDRERKMITIRGSVHQNFVDFTFATSKIIGYLFTLKGDIDSNVAISLSNKASLAFLQKHLGLQKDFDQWDSLVEGEDHNLIPGTNINTTNHQAILQNSTGIERPNLD
The following text describes a protein:
Function:
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.
Sequence:
MAHRTINFLNRISFMKLHNSSSSGVLLAVYMPPNIDIYENFQAGFYLFSWDLVSEEDGSFDSVKSCSLSFVPSEIIFNFCWSDETNLKSFPKLLKFYAVDECNVIWVYTFDTKRKSDRNIVGHHSSFINALVEQPESGLYLASVGDDNRCCLWTANEKNIKDNVVFHLTSPGINVLWNPKEPNKFMVAEKNGMIRFYSAESKKALFSLDSCQNLLSTSDWSSFNSLYVAAMVESDLTVFDTSKSNRPMLVEKVTDSGAVRLAWCPSVDYILTFVSRSKYQLTVLNVKSMKILFTMDLKLYRGFEWHTYLPHLYVADDMNIHIIDISSKI
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSLPNLFYKYVARNNSTWMAAVVVGAFALDTTVNGTVNVIFDGINKDKLWKTVYAERVKKGISQ
The following text describes a protein:
Function:
Antimicrobial peptides with activity against Gram-positive and Gram-negative bacteria as well as fungi. Recognizes carbohydrates in the microbial cell walls, and induces structural damage to them. Also inhibits microbial serine proteases subtilisin A and proteinase K, as well as human and porcine elastases. Carbohydrates that are recognized are LPS, mannan, peptidoglycan, and N-acetl-D-glucosamine.
Miscellaneous:
MISCELLANEOUS: Negative results: does not inhibit plasmin and thrombin. Does not show any hemolytic activity on mouse erythorcytes.
Subcellular Localization:
Secreted.
Sequence:
MYKKGTILVLAYLLIATAVCQLSYKEGHCPLRNSVSKCIPRCVSDYQCSFNEKCCPNKCGSESCVQASPINTGNGYKGSNDDVYCAGVKCGPYEKCQFDRKTKREKCVRT
The following text describes a protein:
Function:
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MGSLFSPKKILQSQYTMILVMIRNIIFLVLGIMLGIRLTDFIGYLKLWRNNDLRASEKAALLKYPVASEEHLATWLRREVRILCLVLTMPSSHATKAALVNRTWGARCNKLIFMSSQTDSNLNILQINKSESRKNLYAKVRTGMAYVHKHYLNEYDWFLKADDDTYIVMENLRLFLYPYDPESSVYFGCRFKAYFSQGYMSGGGGYVLSRDALRRLNLFALNSTTICKLNGESEDVQIGHCLQDVGVIAGDTRDFQGHHRFLPVNPFTVFPTILSNSWLEGYFFHKPNKSDCCAASAISFHYVKDFEFELFEFFLYYMRVFGLHRTPRALPSRLGFRQMNERLQHWSQQVTDNKN
The following text describes a protein:
Function:
Heme-binding protein involved in heme-iron utilization. The ability to acquire iron from host tissues is a major virulence factor of pathogenic microorganisms. Involved in biofilm formation.
Subcellular Localization:
Secreted, cell wall. Cell membrane; Lipid-anchor, GPI-anchor. Note=Found anchored in the cell membrane as well as a covalently-linked GPI-modified cell wall protein (GPI-CWP).
Domain:
The CFEM domain is involved in heme-binding and contains 8 cysteines and is found in proteins from several pathogenic fungi, including both human and plant pathogens. The CFEM domain adopts a novel helical-basket fold that consists of six alpha-helices, and is uniquely stabilized by four disulfide bonds formed by its 8 signature cysteines (By similarity).
Sequence:
MMSFSLLSIVSIALAATVSATSDGTNAYTAYPSVAKTASINGFADKIYDQLPECAKECVKQSTSNTPCPYWDTGCLCVMPQFGGAIGDCVAKNCKGKEVDSVESLATSICSSAGVGEPYWMIPSSVSDALAKAANAASATTSVETATKSAAAELATTSDTTIVASTSHESKVAETSVAQQTASTEKSSAAETSRAKETSKAEESSKAEETSVAQSSSSANVASVSAETANAGNMPVIAIGGVIAAFAALI
The following text describes a protein:
Function:
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
Sequence:
MAELFKFSQKPNLEGFTLLIPSVSVGNVPQLTIDLLITSLNFKKVATIWHPAIVSSVGSDPYRTDGPEICTACELYINEDLKVALIQLRSAINAKLATKFFTDLKNSLTQFKIKSIVILASSFDYELHVVSSNKFYYISNQEITDVMKSLNVKPKEVEFNGKYLVHGSGFAVKLFEVLESNFECTVLIKYVSEGDNRPDAIACINVLNKFVNGFTKCNVTEIKFPSSWNCVFGGPPPLGIY
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MYDGHEVDPEYQKPAKKKVHNKQSNNDLADDMDEKVPCTECNKLIKRSWLKQHMVILHSEERNHLCDECGRTFVIKAQLRAHQLRQHKAVPGNHLCEHCGRSFRFARYLNRHMSLHSSEKPHVCRFCDKAFRLKPVLIKHIRTHTGEKPYKCTVCGRCFRQRTTYATHLKVHEKRQEAGVVGGEGSGLGQLPRLKCDFCSMTFKLDLFLMLHRAKHTGETPALPCPTCKETFPSIKELTLHRKGQHPDTVYSCQICPKVFTNKANFDFHVHKHSNPDAVKKKYPKVDPVDTGPCTCDFCDKVFKNRSALDYHIKGIHLGDKSLKCQYCDKTFSHKPSLEQHMRTHTGERPYKCDQCPSSFKQQQHLTAHLVVHTGERPFSCDHCDKTFPHKTTLYAHLRIHTGKRLMCTHCRKVLPSLAQLMRHEENCHLNTNESSVE
The following text describes a protein:
Function:
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
Subcellular Localization:
Cytoplasm.
Sequence:
MGASSSVPQNSIHEFTVKDCKGKDVDLNIYNGKVLLVVNVASKCGFTNSNYTQLTELYNKYKDKGFEVLAFPCNQFLKQEPGTSEEAQQFACTRFKAEYPIFQKVRVNGPDEAPVYQFLKSSKGGFLGSSIKWNFTKFLIDKEGKVIKRYGSTTTPLAIEADIQKALGEV
The following text describes a protein:
Function:
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MLPLPQLCALWGCLLTAVHLGQCVTCSDKQYLQGGECCDLCQPGNRLVSHCTALEKTQCQPCDSGEFSAHWNREIRCHQHRHCELNQGLQVKKEGTAVSDTVCTCKEGQHCASKECETCAQHTPCGPGFGVVQMATETTDTVCQPCPVGFFSNGSSLFEKCHPWTRFPAPDASPAGHSRRDGHPHHHLCGFSLYQKGGQETKGQ
The following text describes a protein:
Function:
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
Subcellular Localization:
Cytoplasm.
Sequence:
MALATQSNRIKIGIRPTIDGRRMGVRESLETQTIRMAQSVAQLLQTHIRHTDGTFVECVVADSTIGGVAEAAACADKFKRENVGLTITVTPCWCYGSETIDMDPHMPKAIWGFNGTERPGAVYLAAALAGHSQLGLPAFSIYGTEVQEADDTNIPEDVKEKLLRFARAGLAVASIRGKSYLSIGSVSMGIAGSIVNQAFFQEYLGMRNEYVDMMEIKRRLDRKIYDQEEVDLALSWVKQYCKEGVDVNSLENQRNAEERAELWENVVKMTIITRDLMVGNPKLATLNYAEEALGHNAIAAGFQGQRHWTDHLPNGDFMEAMLNSTYDWNGVRPPYILATENDSLNAIGMLFGHQLTGKAQIFADVRTYWSQDSVERVTGWRPESGFIHLINSGSAALDGTGEHQDAQGNPTLKPAWDVTEEEAKRCLENTRWCPAVHEYFRGGGLSSQFLTKGGIPFTIHRINLIKGLGPVLQIAEGWSIDLPQDVHNKLNQRTNETWPTTWFVPRLTGKGAFTDVYSVMANWGANHCVATHGHVGADLITLASMLRIPVCMHNVSEKNIFRPSAWNGFGQDKEGQDYRACQNFGPLYK
The following text describes a protein:
Function:
Promotes differentiation and/or maintenance of the vascular procambium, the initial cells of the developing vasculature. Part of the TDIF-TDR-WOX4 signaling pathway that plays a crucial role in the maintenance of the vascular meristem organization during secondary growth. Is required for promoting the proliferation of procambial/cambial stem cells but not for repressing their commitment to xylem differentiation in response to the TDIF signal. Acts redundantly with WOX14 downstream of the TDR/PXY receptor kinase to regulate procambial cell proliferation and differentiation in vascular tissue, independently of any role in vascular. Acts as a cambium regulator in the inflorescence stem. Is required for auxin-dependent cambium stimulation in the inflorescence stem.
Subcellular Localization:
Nucleus.
Sequence:
MKVHEFSNGFSSSWDQHDSTSSLSLSCKRLRPLAPKLSGSPPSPPSSSSGVTSATFDLKNFIRPDQTGPTKFEHKRDPPHQLETHPGGTRWNPTQEQIGILEMLYKGGMRTPNAQQIEHITLQLGKYGKIEGKNVFYWFQNHKARERQKQKRNNLISLSCQSSFTTTGVFNPSVTMKTRTSSSLDIMREPMVEKEELVEENEYKRTCRSWGFENLEIENRRNKNSSTMATTFNKIIDNVTLELFPLHPEGR
The following text describes a protein:
Function:
Involved in the regulation of flowering time (By similarity). Plays an important role during the early flowering of precocious trifoliate orange.
Subcellular Localization:
Nucleus.
Sequence:
MKTTKGGKVMNPTDAYRKELRKKELKRNKKERKKVREVGILKKDPEQIREQIEKLEMMKADGALDKARKHKKRQLEDTLNLVLKKRKELQEKMKEKGETPVMFSHLGPPRRRTAEEEERAKHPKPEDSAYYHPTLNPTGAPPPGKPPMYLSSIGPRIPLSSDEASSSKTESDDVALPVPPPPPPLPDSGRLGSGDGSVIPASLPLPPPPPPPKPPTSAGANLGMSLPPPPLPPPPPGPPPKDLVAGQPPLPPSQPLQQSVQPPPPGMSGSEREGSLSALSDDSIFKASAQVPSTLPPPPPPPGMPQKSPNTESGGTASEADGNNLSTTTDLPKMVPPPPPPRQQPTVPGPGLMPSVPADVLPPGLSSFPPPPPPPPLDMRPPLSAPGIPGGANHPGMMVPLVPRPPYGPPPMMRPPLPPGPPPTLQEGEYAANRPTVPQKPSYVKSAAPTVVKRPLAQHTPELTAMVPASVRVRRETALPKAKPKPSVSTTVTTIQPATAPVVRQESIACSAAPKSQGKSIDDSYMAFLEDMKALGALDS
The following text describes a protein:
Function:
Serine protease with tripeptidyl-peptidase I activity.
Subcellular Localization:
Secreted.
Sequence:
MNIKFNLIIIILFILFISNVNCKKIKNKKHLTPQRLRRFVEHSKPISLNKKVWKITEIENIFSAQIELTFGIRQRNIVELEDFVWRVSDPNDSLYGSYKTFEEIKEWVKPLDESIDAVKNWLIENDINEFTVTKSGDFIRTIVSIDKAEELLSVRYNKMVHKLSKQSFFRSLDPYTIPRELYDHIDFIGGVNHLPLLSPRPKESSGSAGGGGGGKVNGIGYELESLRNNKQIKSFNDKKVAARNGDPYLSPDLIRKEMNVSQTSTNSTHLGNSQAIAQFLKEYFSPSDLKIFQYRFGLEPSQVDNIIGPNQNLNPGIETALDIQYIMAMAPDVPTWIVSTGGLHEGQEPFLDWLVDLSSNPKLPLVHSISYGDDESSIGLAYTDRVDTEFKKYAAMGRTIVFSSGDFGVGCNDDCDSFSPGWPASSRFVLAVGGVIKKKDGSIIGDEISGGGFSNYFSRPWYQVDECSSYIEWLNGSLSSFYNQSGRGFPDISSFSENVVILYKDKLMPIGGTSASAPIIAGLLSLINDQRLQKNQSPIGLFNPLLYKIARDHPNSFLDIDFGENNYKCCTNGFKSKSGWDPVTGLGLPNFDELVKYCLE
The following text describes a protein:
Function:
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
Miscellaneous:
MISCELLANEOUS: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIPIQLTVFFMIIYVLESLTIIVQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNBFCSYFNLNYVLCNLTITWEFFNILTFWLNSLLTVFYCIKVSSFTHHIFLWLRWRILRLFPWILLGSLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLEKFHQYEFQAHTVALVIPFILFLASTILLMASLTKQIQHHSTGHCNPSMKAHFTALRSLAVLFIVFTSYFLTILITIIGTLFDRRCWLWVWEAFVYAFILMHSTSLMLSSPTLKRILKGKC
The following text describes a protein:
Function:
Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. Inhibits EIF4E-mediated mRNA nuclear export. May play a role in hematopoietic differentiation.
Subcellular Localization:
Nucleus.
Sequence:
MQYPHPGPAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPSPAPTLPSPNSSFTSLVSSYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKEELESLDNACDQRQDLPSEQNEGALDSSQCPPSPRSQEDLESEISEDSDQEVDIEGDKGYFNAG
The following text describes a protein:
Function:
Required for the use of extracellular DNA as a nutrient. Has been suggested to be involved in gluconate metabolism.
Sequence:
MLTVPGLCWLCRMPLALGHWGICSVCSRATRTDKTLCPQCGLPATHSHLPCGRCLQKPPPWQRLVTVADYAPPLSPLIHQLKFSRRSEIASALSRLLLLEVLHARRTTGLQLPDRIVSVPLWQRRHWRRGFNQSDLLCQPLSRWLHCQWDSEAVTRTRATATQHFLSARLRKRNLKNAFRLELPVQGRHMVIVDDVVTTGSTVAEIAQLLLRNGAAAVQVWCLCRTL
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MAERMRGLPPKVTGISPKDGIPGTLLTIRGENLGLNAQDLIHVMVCGFDCILNATYMSQSKIVCKTGFGLGNGEVIVTTKSGGEGTCTVTFLAYAPDRIDPMTPFPMWIPEDTSDDEIATTGVKRKPIAFNDPLGLPVAAESDIPKDELEAYYSSCDSEISSEKFHPIRFLLEKHCNATFDDLKMDVYREAAKNDTWDHGLPTGKLEVSVRESSTLGINLFDETLRRKDKADSIRNALGVLQRFRFLFNLPSNIERNVKNGEFELIINDYDRVRSLFANTEVQVFKKVLNEVELQIDRVRSILKQRLNKHMAPLEEQKRIIRYLVELDTVGDPAWECIVNKQKWIIDLFMSCKEDYLRKDEELVNSNIDLPTPKRKISILNVVPHVDITKKPESSSSTHSEWNSGDKTDGSNRSSIEIDDDVPRLQFMEEMCDLLAENLPSLWKLGKLHMDGAFAAGQAQDQNYVDNNATHQEKPFSVVVGELIRLFSNLVKACFLPATLVDMNSSQRSYLGIWASLKKQNVANEAKILQRCIAALRSCLFRLAPLDIPLSVTGCLQDLCNEIKYRCAITACEASLIDISTHGYYDSWILRNEGDRYLTDAPHRFESTVTKVLLILKEHVLNIKVGEIENKSVSLDMQKDLLTQICKMFLVYNDRLNKIVMDLQLDKEDSSEGDPITKKTSTLEHDLVEGGQSFNQFQRLLVISSDCCYTKDHVLARVIKILHSQNFNTANMHTGIRQEFDSLEKRIFKLYIKYRGNPVVAEMQDNMYVGNFSWDIPRPVQGKNQRFTSFSITLFNVDLMVSVKFSDVSNYVKETLLRLVEVHAEITSVSPRFAEKMMTKLTEHISKQMSRLLRGVNTFSAEGRLQAHCDLSAFAKVAYGHINDRALAEISAAIKYVNAAQAITSESEAIVAKFLKYSEFQFYCFQIQQISSL
The following text describes a protein:
Function:
Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins. Involved in activation of the JAK/STAT pathway. Catalyzes ubiquitination of methylated RBM15. Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA. As part of the PINK1-regulated signaling, upon mitochondria damage, ubiquitinates ABCE1 and thereby recruits autophagy receptors to the mitochondrial outer membrane to initiate mitophagy.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSLNHSGEESSECPLCMEPLEMDDLSFYPCTCGYQICRFCWHRIRTDENGLCPACRKAYPENPADFKPLSTQEMHRIKAEKRQKDQQKKQKATENRKHLANVRVVQRNLVFVVGLSPRLADPEVLKRHEYFGKLGKIHKVVINHSTQYAGSQGPSASAYVTYIRGEDALRAIQSVNNITVDGRTLRASLGTTKYCSHFMKNQVCPKPDCMYLHEIGDDAASFTKEEMQQGKHTDYERLLHEQLLSPCLNHKEGRKASASPPLKEGATNATQSGPKDGWPSLPPGCSTGNPSSLNTSGKVVVPIVKSEPPLTKEKSGKIKAKPAQPSSVHIPVAAVQPEESSLPQAKTNGSNRKAKEKTAVTAVLTAVLNPTAPVTTQPTKPERQRSTSLSPALSTSSNPTPPLVSSSSSPSSSQDSGFLPSNQHEFEILKQGASMAAEEEEIDRARDEAEDYFDPAGNKVTVNSSSFAHSILDTNNSSNSHSFFSTGPLPAYTAQSNGTSPSGCWLANGAEEESITSTLPNQSAADWQLAFNDLASSSRLVPNATAMEDPSNHQSKNTDDDLGFDPFHETQKALAEMLEKESISSLPNGSVFSNGCSNLGYSGPVQSLYSNPPVPPSMTRHSPSFSSLGLGLGLGVGVAPQPQPSRTRIPPPGFNPTQHLAGSMNQGGVSHFGLSLPNLSSNRPVNRLDMGTSKMLPFMNNQSTANGGVGGPSTGYGPRLGHYHESPSLGLGMSGIGGMSGGGMSSNMSYMGGQNGSLSHLSNNKPQGYNTGMGSNMPYSNGSNSLGLGTSGIGDPAPSMKDWQDGLRALFPNVNISMGNGGVTSNNGSSNNSSSHSGRMGAFPPGLSGLGNGQPQQMHHQHHQHQMTQQPNSLAAKGWRNGSDWTSLDPAIVSSGQITDSRSDSPPHWLRSLEQLTETGNSPAQQPPSNPSNLFGLANSTHYNLPSLSGRSNVTPASGLDGLNSMGSFWPSVSHTTPSMPPPGFSHIRPTPKTASTAETHKIDNL
The following text describes a protein:
Function:
Involved in endocytosis.
Sequence:
MARRVSRTALENEIERARVEGRWESLSKLVEQLCTRTTQESQIDSLKILLLAEADLETYSRDHSLDVNDLRAARSALEPVVTKLNNVIQERKKDERSQEAMLLLCKAYFIQGEFQSSVQCCNEAGADDLVIDMHFKRKSRLVAEAFAYKAMALEELKLTGKDEIQEDDIISCYEYAGDIAIWLMAGQKASFAQTYVIGEMSQAIEVAIQRAPILHIKNGRLTQGINRFRQMLQALESKATHNLRKILAQQLAQVLVRGVCERTYEKPNYQNTNIPGSIVSLSRGAGKPEAGKSTAINVMMTRLNSFPLKPLVYASDSLFIPRDEIEEALLLLLLEDSMVLRDAVLSVAPAKAAARSRTVSEANTVYDLLTIALTRRAQYGMLVECLDKGMKLAYEEFHLWFQFALSLISAGKYQRALLVLRQCACLKPDDPLVPLYAAKLCFNHLHQLEEGVGFAKQVVAMGDDNEWASRAYQALGVGYAMQAVEASLSADRQRLHKLAIDALESAHAHDPEDADILFHLALAQAHTRQISRAVKNTCAALKIEGDNLRFLHLMALLLSAQKKFSEALDMCEAALMEYPDDFSLLLTKVKLEEICIGSDQALITCKQLLETWKQVYDSELSSGDMRRAGSGLLDKVIADTRSLKQIPLTEISSEKDGDPETGSIAASVRLEQALSDEAASASIGKLSVSAVLALQSKIWLAIAGVFIGAGKDAEANACIQEANLIFPLSPDVLYQRGRVFEIRGGLNDAKTCYTNAISINPSHAPSMERLGVVYQKLNNLVMAEKMLRETINVDPTVHAAWHHLGTVLEEQGEHEAASECLFTSADLEATCPILGFTTIP
The following text describes a protein:
Function:
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MTTNKSNGNLVKLCIMGDGGVGKTSVTIQFISNHFVHYYDPTIEDSYRKQCLIDDQVYMLDILDTAGQDELTAMRDQWIRSCEGFILVYSVTSRSSFDQVQFFREQIIRVLDRDDVPIMMIGNKSDLDDERQVTFQEGKDLARCLGMSFMEVSAKTRLNVEEVFNETVRCVKRREESLLKKDNSKDGKGDHSKKSSIFKKLNQKVNGAKISICKMM