lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination of target proteins, including p53/TP53, TP73, HDAC1 and CDKN1B. Mediates ubiquitination and degradation of p53/TP53; preferentially acts on tetrameric p53/TP53. Catalyzes monoubiquitinates the translesion DNA polymerase POLH. Involved in the ribosome-associated quality control (RQC) pathway, which mediates the extraction of incompletely synthesized nascent chains from stalled ribosomes: RCHY1 acts downstream of NEMF and recognizes CAT tails associated with stalled nascent chains, leading to their ubiquitination and degradation.
Subcellular Localization:
Cytoplasm. Nucleus speckle.
Sequence:
MTLRGKHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDIEVAQTPMPSEYQNVTVDILCNDCNGRSTVQFHILGMKCKLCDSYNTAQAGGRTVSMDEQ
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MKLLKYPRQLHDGQLLAGCVVGGLLVVVGRDRISAYDCGKLQAAARGELAVREVSAEVELQVEVGEDALRYVAGGEGELVVAGDRQIWAAGADWRSAGRGTRFLTVAQLAGGACVTDVKADGAGLVFVSVSGKDEVWLYATGAWERVGVVTLAAKPVTLVVDPLGELLTVVLQNRSVAVYQYNRQGAVRMHQQLPQYVQTNPLRYSITMSPQGDLLPLVNSIKNGLPSAQLLDRTAGFSVQSTLVGYVDKCKILRFSPRLYEKPNKDKPPTQYNLLASSGNEDGSVIVWNTKRTKPLLNAAKVTDTFINDVQWSRDGTGLFAISNDGYLFIFAFHEVELGRLLDDAELEKLRQSVPRLEPLPPPTPKSLAKSEAKPQQDTKPDAKSSANSVSAKTGKKKIAPTVITSTSMEFNEPSYTVPKDLKRRPKQETQTNGTTTKRPKRDVEPMDFLDTNLLIPNISFSKARLATPKVRMNFQYCNTLQQNLVMEVKNGTGSEQKPTSITLTLKDKEKDMVLFQDFTPRFVTICTCGHSFWACCTEEGIVYVYSNTGKKLLPPMIMGVPVSFLEGCGDYLLCVTSMGQLFCWNVKEGKLKFPVNTIYPLLNPSIRYSDDVLTRAENITMCTTTENGIPLVTLSNGDGYMFDPDMEIWLLINDSWWAYGSQYWDFTNTSHAGSSAAAGNDKEDKKNKYWNADAEYLIEEVKKNKKSVVNYLESKTNDEMTRKGLIRNLQRFAKTILMKEGFENLEDIVTLSHLENRLLVALKLNETNEFTKLLKVYCISLAEMGFKNRLDDVLSWLYNDGEYKVGTIANEKREELLKQILVACADIRQVQRVTTSYASALGLLDVSL
The following text describes a protein:
Function:
Component of the nuclear LSM2-LSM8 complex, which is involved in spliceosome assembly. The LSM2-LSM8 complex plays a role in the biogenesis of the spliceosomal U4/U6-U5 tri-snRNP complex by accelerating PRP24-mediated annealing of U4/U6 di-snRNA. The LSM2-LSM8 complex binds U6 snRNA terminating with a non-cyclic 3' phosphate group. LSM2-LSM8 is probably also involved in degradation of nuclear pre-mRNA by targeting them for decapping. LSM2-LSM8 could be involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA, although involvement may be indirect.
Miscellaneous:
MISCELLANEOUS: Present with 1440 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSATLKDYLNKRVVIIKVDGECLIASLNGFDKNTNLFITNVFNRISKEFICKAQLLRGSEIALVGLIDAENDDSLAPIDEKKVPMLKDTKNKIENEHVIWEKVYESKTK
The following text describes a protein:
Function:
Essential for embryo development.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MDYLLTSPSSLRFSDFISSIPKETDHKWLRFSVNLGDARRSTRTRITCGAISSRRKLAERESAERENRVLVRSLMSRISDREPLVKTLDKYVKVVRCDHCFLLFEELGKSDKWLQCLEVFRWMQKQRWYIPDNGVYSKLISVMGKKGQTRMAMWLFSEMKNSGCRPDASVYNALITAHLHTRDKAKALEKVRGYLDKMKGIERCQPNVVTYNILLRAFAQSGKVDQVNALFKDLDMSPVSPDVYTFNGVMDAYGKNGMIKEMEAVLTRMRSNECKPDIITFNVLIDSYGKKQEFEKMEQTFKSLMRSKEKPTLPTFNSMIINYGKARMIDKAEWVFKKMNDMNYIPSFITYECMIMMYGYCGSVSRAREIFEEVGESDRVLKASTLNAMLEVYCRNGLYIEADKLFHNASAFRVHPDASTYKFLYKAYTKADMKEQVQILMKKMEKDGIVPNKRFFLEALEVFGSRLPGSGSENRKSTRSSRSRDSPKGRGGNQLTEFQDKDNKHVFRAVQDCRKNYLENLSGHDKGSRDESRKPSQEKQPLFASDQNNMMIKEKKELFTRVL
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling. The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane. PEX10 also regulates PEX5 recycling by acting as a E3 ubiquitin-protein ligase. When PEX5 recycling is compromised, PEX10 catalyzes polyubiquitination of PEX5 during its passage through the retrotranslocation channel, leading to its degradation.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MSSANRPQLIRSSQKDEQFQGSLRGQAHEVCQAFAGAKKWLQWRKEIELFSDLAYYCLTTFSGYQTLGEEYVNIVQVDLSKRKVPSLFQRTALICCHTLLPYFLDKELVRLEHELQIETDGVRSSHSGLSSGSHRRSWMWKWVHRKIAALSEQQKKTLVKAVYIVRQSIAFLKRLHLAIFYMNGAFYHLAKRVTGISYLRVRRSVGDDQLVDRSYTFLGAISLLHLMLLLWVQINSFQQRQEAQQKWKLLRRMSYQRAPPHEKSYKRRAKCTLCLEVRRHCTATPCGHLFCWECITEWCNTKTECPLCREKFSPQKLVYLRHYR
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
Sequence:
MRIRGIEPRSVPWEGFSFLINIQVAAKPYGIITHKQSRWEKIEHKKLSTTVIKNSFCKMRIIGLTGGIATGKTTVSNLFKANGFPVVDADVVARDVLKKGSGGWRKVVAAFGDDILLENGEVDRPKLGQIVFGDPSKRHLLNRLLAPYISYGIFWEVLKLWLKGCRIIILDVPLLFEAKMDRWTNPIIVVWIDPETQLKRLMDRDRTSAQDAQNRINAQMPSDLKRSKADIVIDNNGSLEELNENFKKILDQVTKPLTWTEFLVSRQGAMVVIISIVSGVLGCKKLIARL
The following text describes a protein:
Function:
Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import.
Miscellaneous:
MISCELLANEOUS: Maps to a phosphate-starvation-inducible locus previously known as psiC.
Subcellular Localization:
Periplasm.
Sequence:
MKLSRLALLSVFALASAPSWAESVVTVYSIDGLHDGDNSWYQVQFDAFTKATGITVRYVEGGGGVVVERLAKERTNPQADVLVTAPPFIQRAAAEKLLANFNTDTASAIPDANNLYSPLVKNYLSFIYNSKLLKTAPASWQDLLDGKFKNKLQYSTPGQAADGTAVMLQAFHSFGSKDAGFAYLGKLQANNVGPSASTGKLTALVNKGEIYVANGDLQMNLAQMERNPNVKIFWPANDKGERSALAIPYVIGLVQGAPQSENGKKLINFLLSKEAQTRVSELSWGMPVRSDVTPSDEHYKAATAALEGVQSWQPNWDDVAVSLSADISRWHKVTESE
The following text describes a protein:
Function:
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
Sequence:
MSCSSIAERTWLRENCACGECFDAVRSQRRVSFYRLNDDSLTIKEVSETLDANSRKQINITWSDGHQSHFDADWMQLQRNQKSNFTTPKILWNAEKIQGYLAEEAVTYEQVHSDKNMSVIKKVCENLHKYGFVVIKNVPTTQKHMEETVEKISEIRPTIYGKSTLIGIDPDDELLSGYPLNGALKDTAYDDDDLQVHVDGTYFTETPAFVVLFCLKAAKVGGEAVLVDSFHVASQLKTSSPKLFHSLANDIVTFNYIDDQRTYIAKAPTIAVDPVSKEFQCVRYNHLDRGPQKIFITNSTEDPAVATNVINGKHVPGQDNFDDTEEARFYEALSEFSKLTEKEENELILKLKEGELIIVDNWRLLHGRKAYVPPRIQLTSKFAYQWSHDPREGPLKLWFFGTMNLRHLTEQRYLRKRYRIEQRKCQSFVKAMLLKTFSKSLIGSTTAYYTI
The following text describes a protein:
Function:
Kinase that can phosphorylate the tocopherol cyclase VTE1, a key enzyme of tocopherol (vitamin E) metabolism and involved in the recycling of oxidated alpha-tocopherol quinone, possibly stabilizing it at plastoglobules. Also regulates plastoglobule protein composition. Prevents photodamage of chloroplasts under continuous red light, thus working in opposition to ABC1K3. Together with ABC1K1, contributes to plastoglobule (PG) function in prenyl-lipid metabolism, stress response, and thylakoid remodeling. Involved in chlorophyll degradation and in the maintenance of the number of chlorophyll-binding photosynthetic thylakoid membranes. Ensures photosynthetic electron transport by regulating the homeostasis of plastoquinone, beta-carotene and xanthophyll lutein, as well as membrane antioxidant tocopherol metabolism. Seems to affect specifically stability or turnover of D1 protein, product of psbA, one of the four core subunits of the photosystem II (PSII). Required for photooxidative stress responses, including the induction of oxidative stress response genes (e.g. FSD1, CSD1, CAT1, and UTG71C1), to prevent photosystem II core and chlorophyll degradations.
Subcellular Localization:
Plastid, chloroplast, plastoglobule. Plastid, chloroplast.
Sequence:
MESIHCNSLLNPNFSLNQRRRRINHAVLNRRDALLRSLNAVELRRSRTFSAVRTSNFSVTAAATDVGGRNSTDASVMTTAMSGVERGVRVGKSSSALEQLDIERGVCVPFRKYSPETVRSKVLESRGAVVSLVSRGVEIVWTLGLYWSTLTYDFLVGRDEEVVPFRARQLRNLLCNLGPSFIKAGQVLANRPDIIREDYMNELCILQDDVPPFPNEVAFNIIEEELGQPLENIFSKISSQTIAAASLGQVYRATLRATGEDVAIKVQRPQIEPIIYRDLFLFRTLASFLNGFSLQKLGCNAELIVDEFGEKLLEELDYTLEARNIEDFLENFKDDPTVKIPGVYKNLCGPRVLVMEWIDGIRCTDPQAIKDAGIDLNGFLTVGVSAALRQLLEFGLFHGDPHPGNIFAMQDGRIAYVDFGNVAVLSQQNKQILIDAVVHAVNEDYGEMANDFTRLGFLAKDTDVSPIVPALEAIWQNSAGKGLADFNFRSVTGQFNKLVYDFPIRIPERFSLVIRSLLTQEGICFTLKPDFKFLEVAYPYVAKRLLTDPNPALRERLIQVLFKDGVFQWKRLENLLSLAKENVAKMSSNPNLRVKRVESKLDLTDTIKDGARLFLLDEGIRRKLILALTEDSKLHVEELVDVYRLVEDEVDIPTLAMQVVQDLPNVFRDFVLSWSNSVLSDR
The following text describes a protein:
Function:
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MPGMRMRIRGPEGTSTINLPDNAKISDLLSEITSKTSLRNFDIKYGYPPKPLLLSQSEPSLPLSKLGITLNGEQLTINSREERRSDASPKNFAPSASSSTLSTPPQVRDTQTAEAKSFSFSGTHGDVKATSESNSAKSAPPVSLSRKGITGDVPEVPIPELDATLVLRVMPDDNSCLFRAFGTAVLPGDDLSMPELRSIVASAIHCNPEIYSKVVLEQEPDDYCRWIQTPDAWGGAIEMGILAEQFDMEVVCIDVQSLSIHKFHENTSKHRCILVYSGIHYDMLALSPSYSGLENDIRIFDTSDDTIIAKAVELCSKLKERHYFTDTGGMAIKCKDCGVIVHGEAQAANHAQQTGHYNMAEVDT
The following text describes a protein:
Function:
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MQPLHLYGGRNGSWEVKPPALKLRAPAMPEPTPGINIWRDTMERQKWLQKVAVHCDEWLMKISSFAAKYIAATERVLLFTMLTDLPSIEEILLANSDMSRCMYHIEEKSSSGPEANAVVEEEKEERSSGPDEANEVVEEQEVYYMEEQRSSGPTKANEVLEEEDDVINDDNDYCASCNSRYKANAFWICCDECGKWYHEKCVNITSSEAEHKERYECPERVGWS
The following text describes a protein:
Function:
Putative transcription factor, that seems to be involved in anterior-posterior patterning of the slug, probably by controlling the proportions of prestalk and prespore cells.
Miscellaneous:
MISCELLANEOUS: 'Wariai' means 'proportioning' or 'ratio' in Japanese.
Subcellular Localization:
Nucleus.
Sequence:
MASIVMKSQHSLGYPNIGNINRSDYDSYEQQYNNPTGSKQYNNNNNNNTNTNEINNGTNTNLNPNNMYGMYNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNINNNNNNNNNNNNNNNNNNQHLSQSQQLSPTPYSSNSFSKLLSRSTNDLMLDQDDPSKKKRKRTSPDQLKLLEKIFMAHQHPNLNLRSQLAVELHMTARSVQIWFQNRRAKARNMEFKPQLSHGGSDLIYNALGSQNGMNSMGGGGGNGGGNGGGGMNGINNILNGNHNRNLNKYIPHGGNSINGNMGGGGGGGGGSHNHHHHNHNHNHHNHNHNHNHNQPLSNGDCGEKFSVASAWNKILLHPNNIDFLIRYNPDDPNSIDVNARDSKGLSLLFTAAFLGYEYQVRRLIESGANPNIKDNQGNTPLIAASVLGNQPIVELLLEHRADPNLVNDEGVSPLFSACKGGHLQIASSLLDHDAEVSVKTKINGETPLHIASLKGFEKICKLLIETEAKASVIDSNNRTPLHHACIMGYFSIAKLLICNGADMNAIDIDGHTPLHTSSLMGHDLITRLLLENGADPNIQDSEGYTPIHYAVRESRIETVKFLIKFNSKLNIKTKNGQNLIHLSVQFASLMMGQMIFESKGCEIAADDSDDQGYTPLYLAAKAGKTNFVKYLLSKGASKKIALEKLIQENQDKEIIQMLESTVTKSSNNNNSNSNINNINNINNINNINSQPNTNSDNNNNNNNNNFNENYSNGNNEQSQPPGNKFEEDDEDDFYDRVYKKSYTNRIISNSFSYQQKLNSGNGISVNSGNLED
The following text describes a protein:
Function:
Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity.
Subcellular Localization:
Cell surface. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein.
Sequence:
PPKTTTTHPPKTTTTPPPKTTTTHPPKTTTTHQPNTTTTHHPNTTTTHQPNTTTTHQPNTTTTHHPNPNTTTTHQPNTTTTHQPNTTTTHQPNTTTPTTAPPTPTQPANLTQGTYNVTGTDGNVCILAQMTLRLMVQYKNTTNSMVQGVFIVQPQQTRASGNCSHTKSSLMLSFHQGHITFLFTKDSKKNSVFVDSVDVSLNYMFPNAKETNFEATNSSVELFKTRIGHSYSCKNETVIMRPYLYLELSEQKIQAFNITKNTFGPADNCPADKPDYRVAIVVGVVLALLIIIVVIVYLIGRKKRTSGYQAL
The following text describes a protein:
Function:
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKFAYRFSNLLGTVYRCGNLNFTCDGDSVISPVGNRVTVFDLKNNRSNTLPLATRYNVKCVGLSPDGRLAIIVDEGGDALLVSLVCRSVLHQFHFKGSVHSVCFSPNGRKFVVTKGNLAQMYHAPGRKREFNAFVLDKTYFGPYDETTCIDWTDDSRCFAVGSKDMSTWVFGAERWDNLIYYALGGHKDAIVACFFESSSLDLYTLSQDGALCVWQCDTPPEGLRLKAPTGWRADLLQAAAEEKEDGEEGEEETTVRGKATPAAEEQQGKVRYSRLAKYFFNKEGDFNKLTAAAYHKKTHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASIAVNSSGDWLAFGCSGLGQLLVWEWQSESCVLKQQGHFNSMVSLAYSPDGQYIVTGGDDGKVKVWNTLSGFCFITFTEHSSGVTGVTFTATGYVIVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDCSGEVVSAGAQDSFEVFIWSMQTGRLLDVLSGHEGPISSLCFNPVKSVLASASWDKTVRLWDMADSWRTTETLGLTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKELDKVTAKHSAKGKAFTTLCYSADGESILAGGMSKFVCIYHVKEQILRKKFEISCNLSLDAMEEFLNRRKMTEFGNLALIDQDAGAEDGVAIPLPGVRKGDMSSRHFKPEIRVTSLRFSPTGHCWAATTTEGLLVYSLDAQMLFDPFELDASITPARIRAALRQQDFTRAILMAFRLNEKKLLQETLESVPWDEVEVVSSSLPDLYVEKVLEFLASSFEVSRHLEFYLIWTQKLLMVHGQKLKSRAGKVLPAVQFLQKSIQRHLDDISKLYVWPTRGWPPASSVWGTGGQCREGLLPHLGCPTVGREVGRLQVRPGAGGRAPSEETSVLRVRAVEEAVPQRRGGHAATWGRVSPRHPRRCVLCLVCTGAGPCLSLTASWVFRSRGQASLPEAFLLRVPPAGRRRAPLRPTLVLRRWRKGIVPGTPAWGHLLLLHRAQPAFEYSSAGGSSYVAKARFCLDFPRGQSWRPVGPLPLPRSCHMVFYVKHRTREQGCDFCLCSCGELIDLGHPFCSQAARRPLPRGLPGLLGPPASGPEQGRVARTDRHGCIAPQGRAGRSGAHRRGSGAGRARVLMGEKSHH
The following text describes a protein:
Function:
Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, RPS2/us5, RPS3/us3, RPS10/eS10, BECN1, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteracts MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Component of a regulatory loop that controls autophagy and p53/TP53 levels. Plays a key role in 40S ribosome subunit recycling when a ribosome has stalled during translation: acts both by inhibiting formation of stress granules, which store stalled translation pre-initiation complexes, and mediating deubiquitination of 40S ribosome subunits. Deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAVNGAQYIFGEFSPDEFNQFFVTPRCSVELPPYNETVSCGIKSTNEEYQRIEFGVNEVIETESSVLNNTDYSISSTLNPQAPEFILSCAPAQKTPDETNYNSIDCQFSDPTLTLDSGSNAENDGLSGGLGQRERKKKKKRPPGYYSYLEDVSDGVAPTEALVNGHANSSGLNSIGTEDTELTGDIPSLATPRTCNSPDNSVDFVHEAVSDDSVSSALDNTRTAGQPEVCRVTNSEQFCIPSETGRDSPLRTAVVQPYAGTDTTESLGVTNGQTLESSGEDTAANGVELHTVESTDSDQAKPEEASPTTEATATVAGSVPVNQPAKSWASLFHNSKPSASTSVVYVETKYTPPATSTLVPEKQVEVKEGPVPVSEDPVAIKIAELLENVKLVHKPVSLQPRGLINKGNWCYINATLQALVACPPMYHLMKSIPMYSKSQRPCTSTPMIDSFVRLMNEFTNMPVPPKAKQALGDKIVRDIRPGAAFEPTYIYRLLTVIKSSLSEKGRQEDAEEYLGFILNGLHEEMLTLKKLLSPHNEKLSVSNGPEVQTVREEEEQDEQGEGSEDEWEQVGPRNKSSVTRQADFVQTPITDIFGGHIRSVVYQQSSKESATLQPFFTLQLDIQSDKIRTVQDALESLVARESVQGYTTKTKQEVEISRRVTLEELPPVLVLHLKRFVYEKTGGCQKLIKNIEYPVDLEISKELLSPGVKSKIFKGQRTYRLFAVVYHHGNSATGDHYTTDVFQIGLNGWLRIDDQAVKVINQYQVVKPSAERTAYLLYYRRVDLL
The following text describes a protein:
Function:
Key regulator for endosperm and embryo nuclear divisions.
Miscellaneous:
MISCELLANEOUS: At least nine differentially spliced transcript isoforms are produced (Probable). Full-length isoforms, but not the truncated ones lacking the C-terminal domain, are able to rescue disruption mutants (Probable).
Subcellular Localization:
Nucleus.
Domain:
The C-terminus is essential for the function of the protein and it contains two conserved motifs (289-300) and (365-389) of unknown function present in orthologous proteins from various eukaryotes.
Sequence:
MKKPSKKSEIEFCTVCRFHHDQGSRHKYFPRHKSSLSSLLDRFRSKIADVRFFLKNPSVLRPQEQSQNRVWCVFCDEDIVELGSSFACSKAINHFASSDHLKNIKQFLSKNGPAMDCIDEFRISEADVAKWEKKCQSFGNEDASFEGSCGQLSGTSNDIHTKLAFETMDRIKKVPAHHINSYKSNDVMPLQYNTNEYQISLSEIPGVIHNGSYLNMDDSQFPLCDESGNGFGEHSIPCRSKDYSGNGNYCTQENYQVSQDKKQIDGSYNPPGVVGMTSISSSHSTDAGGNVHSGAPPPWLDANDGDFSSVQLNQSDVARFQAKVPGKNRKLNPNRVGAAWAERRKIEIEMEKSGHVTKSNIDPDWLPNFGRVWQSGTRKESRKEFEKEKRKLVKTESISTESEPVKIQPYISKRARRESGE
The following text describes a protein:
Function:
Probable transcription factor involved in the development of gametophytes and seeds.
Miscellaneous:
MISCELLANEOUS: The PHE2 locus is imprinted in gametophytes. Maternal inherited gene is repressed in female gametophyte, while the paternal inherited gene is expressed in the male gametophyte (pollen tube) and in fertilized seeds. The maternal repression is dependent on MEA, which may modulate the methylation of the maternal locus, and repress its transcription; MISCELLANEOUS: This protein was called 'Pheres' in memory of one of the murdered sons of the mythological 'Medea', as PHERES2 is repressed by MEDEA.
Subcellular Localization:
Nucleus.
Sequence:
MKRKMKLSLIENSVSRKTTFTKRKKGMTKKLTELVTLCGVEACAVVYSPFNSIPEAWPSREGVEDVVSKFMELSVLDRTKKMVDQETFISQRIAKEKEQLQKLRDENHNSQIRELMFGCLKGETNVYNLDGRDLQDLSLYIDKYLNGLTRRIEILIENGESSSSLPLPIVANAAAPVGFDGPMFQYHNQNQQKPVQFQYQALYDFYDQIPKKIHGFNMNMNKDSNQSMVLDLNQNLNDGEDEGIPCMDNNNYHPEIDCLATVTTAPTDVCAPNITNDL
The following text describes a protein:
Function:
Transcription activator that acts as a flowering master switch in both long and short days, independently of the circadian clock. Promotes flowering upstream of HD1 by up-regulating FTL1, FTL4, FTL5, FTL6, EHD1, HD3A and RFT1. Seems to repress FTL11 expression. May recognize the consensus motif 5'-TTTGTCGTAAT-3' in target gene promoters.
Sequence:
MSGAAGRECTGGGGSRSSSFSSVSNASPTEVEEEFLRYHTNPLLGGPTTEMRDDGGVTGGPSDQPPLTVKKKRSLPGTPDPSAEVIALSPRTLMATNRFVCEICHKGFQRDQNLQLHRRGHNLPWKLRQRGGPGGGADGGGPPRKRVYVCPEASCVHHNPARALGDLTGIKKHYCRKHGEKKWKCERCAKRYAVHSDWKAHAKVCGTREYKCDCGTVFSRRDSFVTHRAFCDALAQENNKLSQPMNMATVASALQGQAPHHHHHHHLALPSSSQAADDHDNAAGDDDNDGDDFAIDTKSPQLRMLPAMSDSAAADNNNNNNPLFLPPPSMAGCMLSSLQQGGAARPAPPPPASYFSGGGKAAGLYDPSASSPASMSATALLQKAAEMGATAGGYGAGAGFSTVGFGPMMAGPSVMGLFGPVKTPAALSLEVYDGMPLGPTQLVGLDVGRLLPGQHHLYGSSHGHGVGIGSMTRAIGSLMHGGGQQAEQHRRPDDDTRVVDYLGVDDQRTCFSGVSPFGPHIGPWA
The following text describes a protein:
Function:
Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. Catalyzes the hydration of 3-methylfumaryl-CoA (mesaconyl-C4-CoA) to (3S)-citramalyl-CoA.
Sequence:
MSSADWMAWIGRTEQVEDDICLAQAIAAAATLEPPSGAPTADSPLPPLWHWFYFLPRAPQSQLSSDGHPQRGGFIPPIPYPRRMFAGARIRFHHPLRIGQPARREGVIRNITQKSGRSGPLAFVTVGYQIYQHEMLCIEEEQDIVYREPGAPVPAPTPVELPPVHDAITRTVVPDPRLLFRFSALTFNAHRIHYDRPYAQHEEGYPGLVVHGPLVAVLLMELARHHTSRPIVGFSFRSQAPLFDLAPFRLLARPNGDRIDLEAQGPDGATALSATVELGG
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Sequence:
MAPMKVYGWAVSPWMARVLVCLEEAGAEYELVPMSRNGGDHRRPEHLARNPFGEIPVLEDGDLTLYQSRAIARHILRKCKPEFLGAGSLKESAMVDVWVDVDAHQLEPVLKPIVFNCIINPFVGRDVDQGLVDESVEKLKKLLEVYEARLSSNKYLAGDFVSFADLTHFSFMRYFMATEHAVVLDAYPHVKAWWEALLARPSVKKVIAGMPPDFGFGSGNIP
The following text describes a protein:
Function:
Dimethylates a single guanine residue at position 26 of most nuclear- and mitochondrial-encoded tRNAs using S-adenosyl-L-methionine as donor of the methyl groups. tRNA guanine(26)-dimethylation is required for redox homeostasis and ensure proper cellular proliferation and oxidative stress survival.
Subcellular Localization:
[Isoform 1]: Mitochondrion; [Isoform 3]: Nucleus. Cytoplasm.
Sequence:
MQGSSLWLSLTFRSARVLSRARFFEWQSPGLPNTAAMENGTGPYGEERPREVQETTVTEGAAKIAFPSANEVFYNPVQEFNRDLTCAVITEFARIQLGAKGIQIKVPGEKDTQKVVVDLSEQEEEKVELKESENLASGDQPRTAAVGEICEEGLHVLEGLAASGLRSIRFALEVPGLRSVVANDASTRAVDLIRRNVQLNDVAHLVQPSQADARMLMYQHQRVSERFDVIDLDPYGSPATFLDAAVQAVSEGGLLCVTCTDMAVLAGNSGETCYSKYGAMALKSRACHEMALRIVLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASKQALVFQCVGCGAFHLQRLGKASGVPSGRAKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRFHTSERIRGVLSVITEELPDVPLYYTLDQLSSTIHCNTPSLLQLRSALLHADFRVSLSHACKNAVKTDAPASALWDIMRCWEKECPVKRERLSETSPAFRILSVEPRLQANFTIREDANPSSRQRGLKRFQANPEANWGPRPRARPGGKAADEAMEERRRLLQNKRKEPPEDVAQRAARLKTFPCKRFKEGTCQRGDQCCYSHSPPTPRVSADAAPDCPETSNQTPPGPGAAAGPGID
The following text describes a protein:
Function:
Catalyzes the activation of medium/long-chain fatty acids as acyl-coenzyme A (acyl-CoA).
Sequence:
MSTAGDDAVGVPPACGGRSDAVGVPQLARESGAMRDQDCSGELLRSPTHNGHLLVGALKRHQNKPVLFLGDTRLTGGQLADRISQYIQAFEALGAGTGVAVGLLSLNRPEVLMIIGAGQARGYRRTALHPLGSLADHAYVLNDAGISSLIIDPNPMFVERALALLEQVDSLQQILTIGPVPDALKHVAVDLSAEAAKYQPQPLVAADLPPDQVIGLTYTGGTTGKPKGVIGTAQSIATMTSIQLAEWEWPANPRFLMCTPLSHAGAAFFTPTVIKGGEMIVLAKFDPAEVLRIIEEQRITATMLVPSMLYALLDHPDSHTRDLSSLETVYYGASAINPVRLAEAIRRFGPIFAQYYGQSEAPMVITYLAKGDHDEKRLTSCGRPTLFARVALLDEHGKPVKQGEVGEICVSGPLLAGGYWNLPDETSRTFKDGWLHTGDLAREDSDGFYYIVDRVKDMIVTGGFNVFPREVEDVVAEHPAVAQVCVVGAPDEKWGEAVTAVVVLRSNAARDEPAIEAMTAEIQAAVKQRKGSVQAPKRVVVVDSLPLTGLGKPDKKAVRARFWEGAGRAVG
The following text describes a protein:
Function:
Transcription factor that acts as a key player in the regulatory circuit that integrates secondary metabolism and cellular response to oxidative stress (By similarity). Regulates the genes involved in development and stress response through direct binding to their promoters. Particularly involved in the resistance to oxidative stress in asexual conidiospores.
Subcellular Localization:
Nucleus.
Sequence:
MSVDQTLYSRTPTAMADPTCAGPAAFTAAGAFSQPDLMAFSLREEEPIWGFDTIAPSMASWQGKMEQQTFCNPNMERGLKNTHVRNGQPTPPPFDDKKLQTPMGEMYPVAQYAFNSSPPEYAPPKHRSSLSEQSQTDGYGVSTRRRKASAIDQCEQQQEREKREKFLERNRLAASKCRQKKKEHTKLLETRFREVSNKKGELESEIEHLRSEVLNLKNEMLRHAQCGDEAIKIHLAQMVRLITSKDTPNRDLVSPMRSPEQMAASTPHGLSFGFDGPMQLPSEMGSPLDQRRDSEQSIMTESSYTFSTDDSFEELINV
The following text describes a protein:
Function:
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MPGPFSSRSFAATLPNSIAARYRKQLQKHPFLLFGLPFMATIVAGSFMLTPATALRYERYDRKNQQITQEEAMGLRQERRKVNMKDEYYRLQAKDLEDWEQRRVKRLPGEPDGTLV
The following text describes a protein:
Function:
Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
MRISCNQLLLLFSCVWGLTMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCGALHISLITPSFPTEGESQFVLQLRPSIRGALLSLLDHYDWNRFVFLYDTDRGYSILQAIMEKAGQNGWQVSAICVENFNDASYRQLLEDLDRRQEKTFVIDLEAERLNNMLEQIVSVGKHVKGYHYIMANLGFKDINLERFMHGGANVTGFQLVDFSNPMVIKLMQRWNKLDQREYPGSDAPPKYTSALTYDGVMVMAEAFRNLRRQKVDISRRGIAGDCLANPAAPWNQGIDMERTLKQVHLQGLTGNVQFDHYGRRVNYTMDVFELKSNGPRRIGYWNDADKLVLTQDHALLPNETSGMENRTVIVTTIMEGPYVMLKKNWEMYEGNEQYEGYCVDLASEIAKHIGFKYKISIVPDGKYGARDPETKIWNGMVGELVYGKAEIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEEGTDGLPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTDIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPTVFTKTTAEGVARVRKSKGKYAFLLESTMNEYTEQRKPCDTMKVGGNLDSKGYGVATPKGSQLRSAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGGEKDKSSQALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRNEAKRMKLTFTEAMRNKARLSITGSVGENGRVLTPDCPKAVHSGPSLRQSSGLALVSSDLP
The following text describes a protein:
Function:
Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MVNDAAAMAVVRAARPALRGAHDGVAFAAHAAFLADGYSLCAVGPAALADPSPLGDEEVGIDGWNIMENCYAFLYSKEEKGKKKRVLVKCLVIGEVLAIDVLDLEAQDKAPYNIQINVKDFFVEEQPKNYGDMYKNFTSLIETVNSNVLCKLDGDGSGAEAAKSTAAAAAKNSDGRSSPIQSSGDPGPRTADPSGLIYPPIAPIGSDDLYPGPGAGFYPHSGIGSGGSMHVGPNDPRFFPSNPFSAPFGGLGSVPPGSRYDPIGPPDVPGFEPSSFVRRPRRPPGGSTHPDLEFFQQGPDF