lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Effector protein for Rho-type GTPases that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria. In addition to its role in the cytoplasmic cytoskeleton, also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. Promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
Subcellular Localization:
Cytoplasm, cytoskeleton. Nucleus.
Domain:
The WH1 (Wasp homology 1) domain may bind a Pro-rich ligand; The CRIB (Cdc42/Rac-interactive-binding) region binds to the C-terminal WH2 domain in the autoinhibited state of the protein. Binding of Rho-type GTPases to the CRIB induces a conformation change and leads to activation.
Sequence:
MNSGPGPVGGRPGGRGGPAVQQNIPSNLLQDHENQRLFELLGRKCWTLATTVVQLYLALPPGAEHWTMEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYLTPTPFFHTFAGDDCQVGLNFADESEAQAFRALVQEKIQKRNQRQSGERRQLPPPPAPINEERRGGLPPVPPHPGGDHGGPSGGPLSLGLVTVDIQNPDITSSRYRGLPAPGPGPTDKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPCRGGGGGGGGGGGGGGGGGGQPLRPPVVGSNKGRSGPLPPVPMGGAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPPPPPLPGAGGPPAPPPPPPPPPPPPCPGSGPAPPPLPPTPVSGGSPAPGGGRGALLDQIRQGIQLNKTPGALENSVQQPPAQQSEGLVGALMHVMQKRSRVIHSSDEGEDQTGEDEEDDEWDD
The following text describes a protein:
Function:
Cell wall protein which contributes to cell wall synthesis and is important for acquiring normal surface properties. Required for virulence in a mouse infection model.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Sequence:
MRSPSLAVAATTVLGLFSSSALAYYGNTTTVALTTTEFVTTCPYPTTFTVSTCTNDVCQPTVVTVTEETTITIPGTVVCPVVSTPSGSASASASAGASSEEEGSVVTTQVTVTDFTTYCPYPTTLTITKCENNECHPTTIPVETATTVTVTGEVICPTTTSTSPKESSSEAASSEVITTQVTVTDYTTYCPLPTTIVVSTCDEEKCHPTTIEVSTPTTVVVPGTVVCPTTSVATPSQSEVATKPTTINSVVTTGVTTTDYTTYCPSPTTIVVSTCDEEKCHPTTIEVSTPTTVVVPGTVVHPSTSATIITTTAEQPPASPEVSTIESVVTTPATLTGYTTYCPEPTTIVLTTCSDDQCKPHTVSATGGETVSIPATIVVPSSHTTQVEITVSSASVPASEKPTTPVTVAAVSSSPAVSTETPSLVTPAISIAGAAAVNVVPTTAFGLFAIILASIF
The following text describes a protein:
Function:
Cell wall formation.
Subcellular Localization:
Cytoplasm.
Sequence:
MTKTTILLLCGGGSSEHEISLVSANYIQQQLELTPEFHVIRVEMKKEGWFSEQGALVYLDTNSATLNSDKASYPIDFVVPCIHGFPGETGDIQSMLELAGIPYLGCGPEASANSFNKITSKLWYDALDIPNTPYLFLTQNTPSSIDKAKQAFGHWGSIFVKAARQGSSVGCYKVTTEDQIAPAIEAAFGFSEQVLVEQAVKPRELEVSAYEMNGKLYISKPGEVIAPEGTFYSYEEKYSANSHARTVLEAENLTEKHKELIQTYAERVFIHMKLRHLSRIDFFLTQEGQIYLNEVNTFPGMTPISMFPKMLEHNGHRFSEFLVQCVTNTLVNAK
The following text describes a protein:
Function:
Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.
Subcellular Localization:
Vacuole membrane; Peripheral membrane protein.
Sequence:
MKLSIECPSIIAVFLIEKSSSGSSFVFHWPVQPKLEIGENPYSFQTTTNLDDLLNVENDEDLISTKADDYHVLGYEKEFLANFLSPKQELCNQKFELWVDGLTFLGCPIHVGADGEWVKRRKHNPEATMESKNSTGPEQVEPNMSSTPKVTRSRSKRESRISMFHVVFVLNIPTGPEYLPMVTTMYEHILVKLSTALKYEQAKRNYVARECRQITRLTEKCINQNIPFNTYASQIPNHSNLAAALASTFEAISRTDTAHLLINNSIDLSLLWPQPVSTATIEHPELPSRPSLILASQTIFSEEESSPIEPFLAPHWSLLLLQEPEVLMKSLPLSKNSLLASFIANAKPSTTFIKLARTLAIPLSECFMLAKHLIHWRQAIAIPPITPRGTYVTSPTADLSKLASDSILFQKVFPSLPSLSVFLGILSFKPRPFMSIIPSKDHESIYLNMLAWLYRRKWVYEQNTYLYIRVPESIKQKASTILREDKGTDVQLLQQLDADSGQESIINDPHSASLLEQQWLITIANEQEPDLASLFLQIAKYFNGRHALQTISIIEGLPRKAVRNVISRYKLYLIRWNSW
The following text describes a protein:
Function:
Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTTIPRKGSSHLLGSLHTCQLKLQEDRQQQEKSVIAQPIFVFEKGEHTFKRPAEDTLYEVAEPECNGFSRKRVRSSSFTFHITDSQSQGVRKNNIFMISTLVQSNVDIKSAEQGPVKHSKHVIRPAILQLPQAQSCAKVRKTFGHKALESCKIKEKTNNKISEGNSYLSSENLSSARISVQLSTNQHFLGATSVGCQPNEDKCSFKNCSSNFVFGENMVERVLSTQKLTQPQLENDSYTKEKPFKSTPKFPVNFLSSRTDSIKNTSLTESAAAFSSQPSRKCLLEKIDVVTGEESEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASSDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKVFLIQASAKDTAYLYAAIHHRLVALQSFSKQKDVNQAESLSETVQQSNCESCDENEDDFIQVTKNGSDPSRWTHRQSVACS
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
Subcellular Localization:
Cytoplasm, cytosol.
Domain:
The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
Sequence:
MSQQRSTEQIAASNNNTSDVIALDDDEDTDVQFVAALRPTAPVIDLCVSPSTSAAAAAAAAAAAHSGGGSGEDPAVGSASGAAASDTDSLASSPDEGALATGVDAAAAVSGEDSPSAAAAALECPICLQTCIHPARLPCGHIFCFLCVKGVAYKNRRCAMCRREIPAEFLDHPQLVNGIEDICTTRATEDGFQWYYEGRNGWWQYDDRTSQDIEDAFKKGDKSCTILVAGYVYIVDLEQLVQQRQNEPTRCRRVKRDLATIPKKGVAGLRIEGNQVTSDTVFSRPTNTANPTTVAAAASSFISTIAATDAAIRIASDIIGSTLAHADELTRGLTASNLNDDLSSSGEQSNSTNSNDAGRSPASSPASSSMQDLITRDLRNTQQVIAHNQHTIDLFEQALNDFQALAMRNYVDSSDEENNDQDQEHELREREQLEAGEQPQSNDNPQRF
The following text describes a protein:
Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Also has a high affinity for tricyclic psychotropic drugs. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR6 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity. Is an activator of mTOR signaling.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRVRSEEVRTVLFNSPMMSGSPPIPRVEAASDLWKIHRSFNDSSTISDGWSIGGSGPWLLAVMLSLIILVTACGNILLIALVFAHRSLRCTSNCFLVSLFLSDLMVALVVMPPAMLNVLCGTWVLAPGFCPVWLCFDVMCCSASILNLCVISLDRYLLIISPLRYKQHMTPPRALLLVGGAWGLAALTSFLPIKMDWHSLGRMQELTEDDPGNATHLNSFYPSSYFQLSSSGMPSTQCRLRVTLPFALVATFLTFFLPSTAICFTYCRILLAARRQARQVEALTHPAYPQHSLGEPSRPPSPGHAIQDGDDYSHQEPPGLRHAPLSVNSERRLAHRQRKRALKASLTLGVLLGLFFSAWLPFFITNMAQAVCECVPPSFFDAITWLGYCNSTMNPIIYPMFMRDFKRALARLLPCCSSSQAPRRPSLPLSLSLRNSGEPQLPSEPPSLVSDPPQLPATATDAVNLLDAEHAGIDLPLLLPNQVDTLDD
The following text describes a protein:
Function:
Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.
Subcellular Localization:
Nucleus.
Domain:
The C-terminal SGF11-type zinc-finger domain forms part of the 'catalytic lobe' of the SAGA deubiquitination module; The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.
Sequence:
MADLQMYADHFLNEILNEAVLGVAYEAHRSLTKGTLFIDDSDEGDEKYKITIEKGLDIFGQPISGSKKTVECQCPNCNRNMAASRFAPHLEKCMGMGRNSSRIASQRIANSGKFSSTINDSVGADEELDDDNDVDWFACEANQPTKKSKKRKAERGNGSPRTSKSILSKSRSTVTTQSCVAGQSKAFVDQNDNIDVVHDTRSDNINHTVTLWEKHINATLTGNDGGKSPAMHAGNVIIKKKKSKHNPSKKSKRRQI
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDPTFLPQQVSVRALVTFHDVAACFSDEDWRLLEDWQKELYKNVMREIHTALQAMGYTILNPEQLLRVQKGTSQDNEKRKEQEHLLTAGAPVFNPDISLWIREVVEDNFSTSQNPDQTADPDSPTSELTVLKPDIFLRIKPDELVFEACPDPEPENGDTGESDQSVRSGISVTIEREEEPFWLNIQETENEDFGEEQDAGDGFGSRVLEDCLTPFQPDDVPIGNSSHLPQEDWDNTSTIRLPRARKCQSIYRIGQSQCAYDFTDPSSPTPPRAFQCSECQQSFSESEMLLLHQSVHTPWTCNPQEGGGGGVYIPQQPSSALLGGCPVVPAPYICGDCGKGFSSSYKLKIHQRIHTGERPYKCLVCEKRFHKSAHLKVHQRTHTGERPYGCQVCGKRFTKSYHLKVHLRTHTGERPYQCPECLKTFSVNSHLTVHQRTHTGEKPFVCFECGKSFRQKTSLLGHQKSHQRLGERRKLTWKTLWPEK
The following text describes a protein:
Function:
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MVYNEKNGGGIPPVPLSLNTATPWQNVNLHNDQQTEPQLKSHPDTDPRITPYLGLRARLSQLWFNRWTILLILVLIRVIILTANLKENLGDAKAKALSACTKVEDVGSAMASMPYYMSKGVNVMAAGSMQKAVEAMASVLKMILTGVQAIIMFVINMYIGTFACLVAAFIHGGLHVATAVVEGATKVMNDAISSITKGITDDMKSFQSAIDKARDFINSGIGLISKDIQLPTINIDSHIRDLQGIKINANGVVNGLDVLDQKIPTFDEAKNLTESALAIPFNLVKGKIDTAFSEFTIEPTIFPTAEKQALSFCSNNSFLNDFFESLITLVYKAKIAFLVVIIILALLAIFVMGYIEYRGFKRERERAARMDANAFNSQDAIYIASRRWTADGGMRLAKWWTKDTDSKNYLLIRWAFAYATSLPALFVLSLAVAGMLSCLFQWVLLRQIEKKAPELAAQVGDFAGDVVGTLKQVSNNWANSSNAVVANMESDINSDLFGWVREATESVNNTLTVLDDQIDHALVAVFNGTVLLDTARDVVGCLIGRKIDAVQDGLTWVHDHAKVTLPRFDDDIFSAGAAQSMGSDGDLSSFLAKPGAVTTDEINEAVGKVIRSLRNGVIQEALITLGLFLTYVIVVLIGVMGALIGWATPGKTRGEGGQQFGGRPPSFHNHNGFDPALAPSNAMVGNPASPHYQNEKFGGGGGMHDVASPAYEEVVYAGRVPVGNTRELITRYPSHQRTSSYPTVESPDPMPHGDEKVPGYFTPI
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MRIIKPNWVIHPDDKGNPQTIYSAHVHPDGTRLATGSIQNVVKIWSTAPILDPAVEETGEEKAPRLLCAMEGHDGAVLCVRWAFSGAFLATGSDDSIIMVWLRCPGQSKSFGSKTANIEDWKCFKRLAGHTSDVQGLAWSEDDQYLASVGLDSLVLIWDCLDSAFVLLKRLDLHQGHVNGVVWDPVGQYLATQSDDRTVKIWRTTDWKLEADIEEPFVNSPHSFFRRLSWSPDGTHIVTPNAMNGPVFVSAVIDRCKWTSNISLVGHENVVEVAAYNPLLFLRDRSKPIEGPNLSTVFALGARNSVSIWHNCSSCPIVVLHDVFDRDILDLSWAADGITLYACSSEGRVAAFVINELTTLAAVAPPGAKAKYLETYEFTKPDRRSQKSRSSSTPFAPRYASPMPPIGPYRPGRSSPPPSALVPNSMPSNTLITQQEMTIMPNGKRRIKPAFLGTNESAIFLSAMPNGHASTPVQQPNSSQNSHTLFPQSNRFPQATPSTSTLLPTRHAVPTYLSDDLISSNSVSRELAEIMHWNDFGKWGEPIAMPTRILKRVHCNQTEFQVNCENTQGDMDAECSEVVLSSNKTDKKEELWKERFSDKSITAASLSTSHVAIGLSDKSLSVYSYAGRRVMPVIVLDCPCFKIQFRGNLLMSISLKGTVMVWDLTNFKAISGPSKLKHLCDSRALISFTALTHQGAPIVKVRKESLFVFDEDLKSWTVLSGHTMDEMKDKDRLDHRQLKFPSGSPFLVDSALVLAANKPDLLGCIVDHVRFLRDHNRFQVVDELCHELWTGSGWISNRNSKYLSATPTFKLSRMERIKLLYQVIEVLDENPEFRPICQEYSLLLKHNDT
The following text describes a protein:
Function:
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
Subcellular Localization:
Secreted, extracellular space, surface film.
Sequence:
MEGTRLVWLLTLSAAAVLSGKVPVKDDCAQGPEFWCQNLMTAAQCGAVDHCKQNAWLGTDVLCVQCKQIVNILLDMVKASPIQDTIKNFLHKQCSHLPVVPLIAQCNLLVDQYETMMVTVLEKQVNPEALCSSLRLCSSDQAEFWNSELLQEKLFPLIQEHLYNAHVKATQGESEGADLPIPKPMCWMCKSFMSQLEAVIPKTVIAKAATKLCLILPASIAGVCQCLVEKYTIILLDIVLEKLGPQLLCKLLFMCATDENCEAGLTVIPVLDADFTCDTCLAVTSAIKPTIRQNMTQAEVEAAVLKAHGEPGMAWKEIQTFLKNHHTELSLLLHKQWDHRMTCQALGACPAPANAAPQHSGCAVGQSYWCRNLETAKECGAISHCLTHVWH
The following text describes a protein:
Function:
DNA replication licensing factor, required for pre-replication complex assembly. Faithful duplication of the genetic material requires 'once per cell cycle' DNA replication initiation and elongation. Central to this control is the tightly regulated formation of prereplicative complexes (preRCs) at future origins of DNA replication. Required for the recruitment of the MCM2-7 helicase complex to the replication origins.
Miscellaneous:
MISCELLANEOUS: Present with 2190 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Undergoes cell cycle-dependent changes in its nuclear localization. Exits the nucleus and remains in the cytoplasm during S phase through early mitosis, and re-accumulates in the nucleus around the end of mitosis.
Sequence:
MSGTANSRRKEVLRVPVIDLNRVSDEEQLLPVVRAILLQHDTFLLKNYANKAVLDALLAGLTTKDLPDTSQGFDANFTGTLPLEDDVWLEQYIFDTDPQLRFDRKCRNESLCSIYSRLFKLGLFFAQLCVKSVVSSAELQDCISTSHYATKLTRYFNDNGSTHDGADAGATVLPTGDDFQYLFERDYVTFLPTGVLTIFPCAKAIRYKPSTMATTDNSWVSIDEPDCLLFHTGTLLARWSQGMHTTSPLQIDPRANIVSLTIWPPLTTPISSKGEGTIANHLLEQQIKAFPKVAQQYYPRELSILRLQDAMKFVKELFTVCETVLSLNALSRSTGVPPELHVLLPQISSMMKRKIVQDDILKLLTIWSDAYVVELNSRGELTMNLPKRDNLTTLTNKSRTLAFVERAESWYQQVIASKDEIMTDVPAFKINKRRSSSNSKTVLSSKVQTKSSNANALNNSRYLANSKENFMYKEKMPDSQANLMDRLRERERRSAALLSQRQKRYQQFLAMKMTQVFDILFSLTRGQPYTETYLSSLIVDSLQDSNNPIGTKEASEILAGLQGILPMDISVHQVDGGLKVYRWNSLDKNRFSKLLQIHKSKQQD
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Cell envelope. Secreted.
Sequence:
MESPLLFLITLLCFLQSLLVASHNLSKSSTICKTTPDPKYCKTVFPHSQGNVQQYGRFSIRKSLSQSRKFIRTVDKYLKRNAHASPPAVTRALQDCRFLAGLTMDYLLTSFETVNETSTFKTLSFPKADDVQTLLSAALTNEQTCLEGLTTAASSSATWTVRNGVALPLVNDTKLFSVSLALFTKGWVPKKKKRAGYPWAHPSSGTSTHTKPFRLFRNGALPLKMTERTKAVYESLSRRKLTDGAGDGDDGSMVLISDIVTVIQDGTGNFTNITAAVGAAPNNTDGSGGFFLIYVTAGIYEEYVSIAKNKRYVMMIGDGINQTVVTGNRSVVDGWTTFNSATFAVTAPNFVAVNITFQNTAGPEKHQAVALRSGADFSIFYSCSFEAYQDTLYTHYLRQLYRECDVYGTVDFIFGNAAVVFQNCNLYPRKPMPNQFNAITAQGRSDPNQNTGTSIQNCTIRPADDLVLSNYTVETYLGRPWKNYSRTVIMESYIDGFVEPVGWREWNGDFALSTLYYAEYNNTGPGSNTTNRVTWPGYHVINSTDAANFTVTGLFLEDDWIWKTGVPYTSGTNLTAYDVVQKYKLPRGILPEGVIDYDLNPKTGFFKVYLNNTCRFPIEVYKVKYQPIVSGFIKNGRVSRLKGVSVKVLYFWLSIGEVTSDGQELELSVGAASEEFSAHQFARSPQCGCGFYCRELKFSS
The following text describes a protein:
Function:
Substrate receptor subunit of a cullin-RING superfamily E3 ligase complex (CUL5-based E3 ubiquitin ligase complex) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Depending of the metabolic state of the cell, promotes the proteasomal degradation of IMPDH2, the rate-limiting enzyme in GTP biosynthesis or protects IMPDH2 by stabilizing IMPDH2 filaments assembly. Implicated in different cellular processes, like copper homeostasis and cell proliferation.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasmic vesicle.
Sequence:
MPWDTRPGRSANGGPEGPGAARLRVQKQCRKSSFAFYLAVRDLLPVWLLEDMRASEAFHWDERGRAAAYSPSEALLYALVHDHQAYAHYLLATFPRRALAPPSAGFRCCTAPGPHVALAVRYNRVGILRRILRTVQDFPVEERVRLLDRRGCSRVEGGGTSLHVACELARPECLFLLLGHGASPSLRDGSGFTPLELLLHQLNQDASSAPTAAEAASATVPAATATTTSSGEVCQRRLLLLDLLALYTPGGIVGPARCELLGDRLRWQRLLGEDKFQWLAGLAPPSLFVRAMQVLVTTISPGRFPEALDELPLPPFLQPLDLSGKG
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
Subcellular Localization:
Cytoplasm.
Sequence:
MESGAGYQRVPPSFFITLWSLFIFSTSSSEGGGCSGTHLHADTHQMNSGLMMKQLFSPHGSKRVSAVTPDLFPETTLLPSLPAIPSPRTSSAAQQLRRRRSSVGYAASKPLPLGSACRRGPHRGSMEVGMRVVRGLDWKWGNQDDGEGHVGTVVEIGRQGSTTTPDKTVVVQWDSGTRTNYRTGYQGAFDLLLYDNAQIGVRHSNIICDSCKKHGIMGMRWKCKVCFDYDLCTQCYMNNKHDLSHPFERYETAHSQPVSLTPRQNLPRIILKGIFQGVKVVRGPDWDWGNQDGGEGKVGKVVDIRGWDTESGRSVASVTWSNGTTNVYRMGHKGKVDLKYVSDGQGGFYYKDHLPKLGEHAELQRQESADGHSFQQGDKVKCLLEVDILRQMQEGHGGWNPKMAEYICRIGTVHRITDRGDVRVQYSNNIRWTFHPGALTKVNTFGVGELVRVLDEVETVKRLQAGHGEWTDSMTPVLGQVGKVLKVYADGDLRVAFGGQTWTFNPACLSAQPVDVDANLMTTENPNESGSTVISVLEKLLSQSTEQDNPCRLVIEAAHGSAVKVRELVQKHPDKVDIKNQGKTALQVAAHQGHMEVVKALLQANCSVEVKDEDGDTALHYAAFGNQAEIARLLLSKGANVNLLNNSMCTALHIAVNKGFTDVVRVLTEHSADVNLQDSYGDTPLHDAIAKDFRSIIEMLVVVPSIDFTQQNHRGFNLLHHAALKGNKLATEKILARARQLVDVKKDDGFSALHLAALNNHRDVAEVLVKEGRCDINVRNNRNQTALQLAVTQGHTELVQLLVDEGADVNMEDEDGDTAMHVALLRPQLANVMLSPAVGTGATEDNSEGCSPTTLHGRLSSSGLLGNGELSVGTAIACFLAQEGADINYANHKGKSPLDLLADSGALQLIKSFSEKHRLQRLQAITCGQGLSSASLRRVHTTPNTMTNLVLPTPPGPSECLICSELALLVLFCPCQHSVACEECAHRMKKCIKCQVTITKKIRQDQTEVDCSPGTENSEQHNLLEQLQSRYRQMEERITCPICIDNHIKLVFQCGHASCIECSAALKTCPICRQTIRERIQLFV
The following text describes a protein:
Function:
Hydrolyzes acetyl esters in homogalacturonan regions of pectin. In type I primary cell wall, galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions. Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MMMAKTFQFVCVLICFLAIIINIKACVKENATSYIDQGYYVEKTVVHSAVSKGAVCLDGSPPAYHFEPGFGDGVGKWLVHLSGGAWCTTVEECLNRSKSDFGSSNYMKPWWFQGIYSKTQSVNPDFYNWNKVFVRYCDGGAFTGNAEYVDPATNLHFRGARIFKAVMEDVLAKGLKNAQSALLIGSSAAGYPAMLYCDRFRKLLPNTPRVKCLVDAGYFIYNCILTLELSFSNYRKDPHQARNFTEMYKAIVNLHGSAKTLPKSCTKKMKPEMCFFPENMQHKIKTPLYIAMSPFDKFQINTTIYNGINTCIEGGNCTATENKLFREFRLEFLNALPKGNNPKLRGAFIDARNHHTQVQGWWSPKNVTTVKNLNLMKAFADWYYDRNYTYVIDERDLPISAMNDIKPCDTKK
The following text describes a protein:
Function:
Transcription activator that acts as a flowering master switch in both long and short days, independently of the circadian clock. Promotes flowering upstream of HD1 by up-regulating FTL1, FTL4, FTL5, FTL6, EHD1, HD3A and RFT1. Seems to repress FTL11 expression. May recognize the consensus motif 5'-TTTGTCGTAAT-3' in target gene promoters.
Sequence:
MPPNPTEPEQPEAAATPAPPKKKRNLPGTPDPDAEVIALSPGTLMATNRFVCEVCGKGFQRDQNLQLHRRGHNLPWRLRQRGPGAAPPRRRVYVCPEPGCVHHSPARALGDLTGIKKHFCRKHGEKRWACPRCGKRYAVQADLKAHAKTCGTREYRCDCGTLFTRRDSFVTHRAFCGALVEETGRVLAVPAPPSPRPPDLQEVEENVDKDKEKEEENVDKHKEKEDEEDKGGEDENETSAVAEVDEPQNVEAAMEEPQQQRIPPSPSPTPTSPTPQEQQPMVAVVPNLDEPVVVVEPIVDIKQEEEDKRDEDVCFQEADKYDGAELEDSNLPDNDTPMPPCFLPSPSDAIGTDGSSTSCGTVSSASNSIAPATTTSTFAGLFASATTSTTPQSRSLRDLIGVDPTFLCLAIGTPSSLFPQTDASNPGTFAPPPAPHISATALLQKAAEAGASQAGTSFLKEFGLASSSSSTPSRPPQGRFIESSSMQSQQPQGRFIESSSTQSRLPQDRFIDSSSTQSQLPKDRFIDSISTQSRLPHDRFIESSSTQSRLPQDRFIESSSTQFRLPQDRYINNSMPSKLSQGRFMDTSLPSQQLLPQGRFFDNSPASNLSQGRFFDNSQPSNPPQGRFFINSPSSNLPHGRFTDYSSPGRLPQGMYIDGLPQSRLPQGRYMDNSPPAKLPPQGGRFVDSNQQQWHQRSNNHNQLMDMEPGPMVSGSLGLGLAYEGSNPRLPDLMMGQSPLLGPKPATLDFLGLGIGGTMGGSTASGGLPALMVGGELDMGSAAQPPSPWEEAQRKTNGRTIL
The following text describes a protein:
Function:
Necessary for protein translocation in the endoplasmic reticulum.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MEAIDSAIDPLRDFAKSSVRLVQRCHKPDRKEFTKVAVRTAIGFVVMGFVGFFVKLVFIPINNIIVGSS
The following text describes a protein:
Function:
Binds to tRNA and functions as a cofactor for the methionyl-tRNA synthetase (MetRS) and glutamyl-tRNA synthetase (GluRS). Forms a complex with MetRS and GluRS and increases their affinity for cognate tRNAs due to the presence of a tRNA binding domain in its middle and C-terminal part. Binds specifically G4 quadruplex nucleic acid structures (these are four-stranded right-handed helices, stabilized by guanine base quartets). Also required for cytoplasmic confinement of the synthetases and tRNA.
Miscellaneous:
MISCELLANEOUS: Present with 57700 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Note=Largely excluded from the nucleus.
Sequence:
MSDLVTKFESLIISKYPVSFTKEQSAQAAQWESVLKSGQIQPHLDQLNLVLRDNTFIVSTLYPTSTDVHVFEVALPLIKDLVASSKDVKSTYTTYRHILRWIDYMQNLLEVSSTDKLEINHDLDLPHEVIEKKKKAPAGGAADAAAKADEDVSKKAKKQDHPRGKPDEETLKKLREEAKAKKAAKKAANAKQQQEQQNKAPEKPKPSAIDFRVGFIQKAIKHPDADSLYVSTIDVGDEEGPRTVCSGLVKHFPLDAMQERYVVVVCNLKPVNMRGIKSTAMVLCGSNDDKVEFVEPPKDSKAGDKVFFEGFGDEAPMKQLNPKKKIWEHLQPHFTTNDGLEVIFKDEEEKDHPVRKLTNAKGESFKVASIANAQVR
The following text describes a protein:
Function:
Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance.
Subcellular Localization:
Mitochondrion.
Sequence:
MIQVMALRTMSTLQTSMRSITGLCKQNIRQGFLRPGCATIFPRNCTGKYQSHIGQLPSRVTSCRKKQVPDFQGIAYKNTQPLMSFSRNFQTSKSHQLRYIPERRSHTTSKSGIIGGSEGKGGDFRDTLDALVAESIKEEDLGPMNSDEMDDEDEIFISQSGKMLLFPWRLVNTSREGCSDEEREVIRKDKTKVPSVTAILQKTMSPDSAAALLRWERFMIKKMGLPAFQKLKKEMFSEGHQLHANIGHILLNKPEEVVIEKGIEGFWKSIKERLPELASDSPIIECHTRHPYLGYHGYADCVTEYRGKPCLVEFKTSRKPKKSLSKCFDNPMQVAAYLGALNFDPKYQFQINQALLVITYKDGSPADLHVMTPELCDLYWNKWLKRLQEYREMEGRKTAEQL
The following text describes a protein:
Function:
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MNQNNTINIRAIRNKKSIKKDLSLQPKNIHDQYYQESDDSEDEKILSKIGRLQTKKYKDKDFIGYDENLNKIQKKKQFQDTIDEFINKTENKDWWRVVRDELNNQDVVLSDKQLQLLDRIRTGKTAIKLSDDYYFEHEDFNQFDLLSSYNPKRRFLPSKWERIKINKLVQGIKLGRIVLNPPQKVEKMFDIWENVAEDQVLSKYLPARIPASKAQLPSNVASYNPPEEYLFTEQEKQQWLQTDPEDREIPFIPQKFKHLRNVPSSEQLAKDLFNRCLDLYLAPRIRRKKLMMKSTDFLPEIPKPEELKPFPTKLNFEFGQIDTTKSGQVKQISISQDGQLLGVCYEFAIAFFDTKTSKCLYTKWQSDDKQFLGLDFSSSGLICILQSNGFIILNSYIDKRQHPNVEDGEKANKQIPKNSNNVFEWNFELDDNVFQQLLEVKMPYDPLYAQFHSKSDYIVSTQPHTHVKSHCILVHSISKSSTSIPFQNMKASTEVQQTIFHPTKPELYIMTNKNIFIYSLTKQQLMKKLLAGNQQNSTIAIHPYGDNLIVGSNDQKVCWFDLDMGKTPFKKMSYHKNGVRRVIFHKTYPLFASCSDDGTINIFHCRISTDLNQAPVILPLKVLKQKKKESVMDVAFHPTQPWIYSASKEGVVSLWT
The following text describes a protein:
Function:
Specifically deaminates adenosine-37 to inosine in tRNA-Ala.
Sequence:
MCDNKKPTVKEIAELCLKKFESLPKTGKPTANQWTILAGIVEFNRNTEACQLVSLGCGTKCIGESKLCPNGLILNDSHAEVLARRGFLRFLYQELKQDRIFHWNSTLSTYDMDEHVEFHFLSTQTPCGDACILEEEQPAARAKRQRLDEDSEMVYTGAKLISDLSDDPMLQTPGALRTKPGRGERTLSMSCSDKIARWNVIGVQGALLDVLISKPIYFSSLNFCCDDAQLESLERAIFKRFDCRTFKHTRFQPQRPQINIDPGIRFEFSQRSDWQPSPNGLIWSQVPEELRPYEISVNGKRQGVTKKKMKTSQAALAISKYKLFLTFLELVKFNPKLSEMFDQQLSDPERIAYASCKDLARDYQFAWREIKEKYFLQWTKKPHELLDFNPMSNK
The following text describes a protein:
Function:
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
Subcellular Localization:
Cytoplasm.
Sequence:
MSNHRTILHLDMNAFFASVEQQADPSLQGKPVAVIGSGARTIITTASYEARAHGVGTGMTTHEAKRLCPELILVIGNNREYTRISKLIFEMLGQFTPLVEVFSIDEAFLDLTGSLRLFGRADVIAREIKARIRDRFGLTCSIGIAPNKLLAKLASDMQKPDGLTIIPPENVASLMKTTPIRSLCGIGPSTEQRLKYLGISTCNDLGHFSSKILTRHFGAMGARLKQMGQGIDDSPVIPTTTEEEVKSVSHSTTLDHDLTNKDDIHKYLLMLSEMVGRRARRYKTKGKTVTLTIRYADFTTFSRQETLPSPLNRSGDIYRAVTALLDTLQLTQPIRLLGVAISNLVHASEQLPLFPEERRLTTLSQAMDQVNDRFGETTITFGTLLGQDNCSHVIAPAWRPAGIRDVKVK
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSSLYRQHSRIFQISRLLYFTPCSYNEELGHFVATKSNLTVFGVALVLTISFWVYDIHLMATNVLRTYTTVFAAVGGIELLIYVSVVICTILNVFVKRQRITRLMNVLFRPDRILDRCSPTNSADARYNDNRKLLAFALFILFGIFIKLFHLKTAELKILRMMTAGRFFTIWMLIFVHRLHVRAIGQRMEQLRVMYASEELEQHLDYFLHRYDRYSRQIGEVDDCYSFPVVLVLLLVMLQLIYLAEHLYSTIETGRMMPVADNFFYSLFSQVWQTVYGALGYYCISACGTASEEVEETALCTRHFDDYRLQNTRAAKQIQKFLLKNLHQKKKFSACGFFDIDNTVIYMVFSSIVTYLVILIQFKQLETDLTQSGDGYNVTSNVSTVQP
The following text describes a protein:
Function:
Functions as a transcriptional regulator.
Subcellular Localization:
Nucleus.
Sequence:
MEKCSVGGLELTEQTPALLGNMAMATSLMDIGDSFGHPACPLVSRSRNSPVEDDDDDDDVVFIESIQPPSISAPAIADQRNFIFASSKNEKPQGNYSVIPPSSRDLASQKGNISETIVIDDEEDIETNGGAEKKSSCFIEWGLPGTKNKTNDLDFSTSSLSRSKTKTGVRPFNPGRMNVAGDLFQNGEFATHHSPDSWISQSASFPSNQKQPGVDSLSPVALLRKQNFQPTAQQQLTKPAKITCANCKKPLQKGQTAYQRKGSAHLFCSTTCLSSFSHKRTQNTRSIICKKDASTKKANVILPVESSKSFQEFYSTSCLSPCENNWNLKKGVFNKSRCTICSKLAEIRHEVSVNNVTHKLCSNHCFNKYRLANGLIMNCCEHCGEYMPSKSTGNNILVIGGQQKRFCCQSCINEYKQMMETKSKKLTASENRKRNAFREENEKQLYGSSNTLLKKIEGIPEKKEKTSQLQLSVECGTDTLLIQENVNLPPSSTSTIADTFQEQLEEKNFEDSIVPVVLSADPGTWPRILNIKQRDTLVENVPPQVRNFNFPKDNTGRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCKLFGEGKNQLKNENGCKDWQHLSHILSKHEESEMHVNNSVKYSKLKSDLKKNKAIDAAEHRLYENEKNDGVLLLYT
The following text describes a protein:
Function:
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MAENRRMKKVNAMLREAIAKVILKDVKHPKISNRWITITRVSLSRDLQSACVYVSIMPHENSQEETLAALKASAGFIAFQASKDLVLKYFPDLNFYVEDIFSPQDHIESLLLKIAEQDKKTNP