lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.
Subcellular Localization:
[Pro-neuregulin-3, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein. Note=Does not seem to be active; [Neuregulin-3]: Secreted; [Isoform 3]: Cell membrane; Single-pass type I membrane protein. Note=Isoform 3 is also proteolytically released as a soluble form.
Domain:
The cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing involves initial intracellular domain dimerization (By similarity); ERBB receptor binding is elicited entirely by the EGF-like domain.
Sequence:
MSEGAAAASPPGAASAAAASAEEGTAAAAAAAAAGGGPDGGGEGAAEPPRELRCSDCIVWNRQQTWLCVVPLFIGFIGLGLSLMLLKWIVVGSVKEYVPTDLVDSKGMGQDPFFLSKPSSFPKAMETTTTTTSTTSPATPSAGGAASSRTPNRISTRLTTITRAPTRFPGHRVPIRASPRSTTARNTAAPATVPSTTAPFFSSSTLGSRPPVPGTPSTQAMPSWPTAAYATSSYLHDSTPSWTLSPFQDAASSSSSSSSSATTTTPETSTSPKFHTTTYSTERSEHFKPCRDKDLAYCLNDGECFVIETLTGSHKHCRCKEGYQGVRCDQFLPKTDSILSDPTDHLGIEFMESEEVYQRQVLSISCIIFGIVIVGMFCAAFYFKSKKQAKQIQEQLKVPQNGKSYSLKASSTMAKSENLVKSHVQLQNYSKVERHPVTALEKMMESSFVGPQSFPEVPSPDRGSQSVKHHRSLSSCCSPGQRSGMLHRNAFRRTPPSPRSRLGGIVGPAYQQLEESRIPDQDTIPCQGIEVRKTISHLPIQLWCVERPLDLKYSSSGLKTQRNTSINMQLPSRETNPYFNSLEQKDLVGYSSTRASSVPIIPSVGLEETCLQMPGISEVKSIKWCKNSYSADVVNVSIPVSDCLIAEQQEVKILLETVQEQIRILTDARRSEDYELASVETEDSASENTAFLPLSPTAKSEREAQFVLRNEIQRDSALTK
The following text describes a protein:
Function:
Forms a channel of about 1,7 nM through the cell membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 20 mv. The open state has a weak anion selectivity whereas the closed state is cation-selective.
Subcellular Localization:
Mitochondrion outer membrane.
Domain:
Consists mainly of membrane-spanning sided beta-sheets.
Sequence:
MNPGLYADLTKPTADFIKKDFAETFKLDTTFKGKYGSIVAVTDIKDSGVVASIQPKADFTKYLGKVSNGNFTVDTNGVKKGEFTIENIIPGLKAVANGDSKQNFSTEFQYKKDKIAFTLFGHNNKSFNTSLAFLINPTFSVGVQAEGNAKNTLKNVNATITIRPRPDVFVSIVDRFMDKQILLSTLYTATSKLSFAGDVTVDLKASEKAPSFNVGTQYKIDSASLLKAKVNNNRKVNISYIYNTSNNTKFVLGWNVNTKNFKQGNTFGATVNLTL
The following text describes a protein:
Function:
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Sequence:
MSGNVACARVRSQSSTFSPLETRDGDEQESSSSDSQHGSSKRGPQRRATDLPSAADLYVPSLPGLPEMATHPTHPLNIYAGMLPSYPGEGKVGGEGQTGKDAKLYFLMAKARRNAGKERVIFWFNGGPGCSSFDGSLMEVGPFRTVPATETTSGMVEAKLVEGGWEEFATVVFVDQPPGTGYSYAATDGYLHDFDELSAHFIEFLQNFYTVFPELKGVDTYLAGESFAGQYIPFFADALIKSIELPNFPLKGIAIGNGWIDPKEQYPGYVEFAYEKGLIVSGTPEAEEMESALKRCQEEMDKYSDPFTTPVNINNCGQVMDSVTRPFTQELNGKKVCMNVYDVRLVDDFPACGMNWPPDLPDVYTFLRQDDVISALHATSKETAWVECNNKVSYELNLKKSHMSAALLPSILEAGVPILMFAGAEDLICNYKGIERIVNGLEWDGEKGFGNATSQEWYFNGTQVGTWQTSRGLSYAKIFDSSHMVGFDVPHVSNDMIMRFMDVDVSLLPGMTAQWPSRIGDDERTMIHVGDGESGGVPLIEGGNTDWEAWYNAIFAFLVLGILVSIAGLYFYFRRKPVSYRSRISLKQRSRRHRGHDMDEDEAAERMPLGSERLELDDIERAEGYEFHDGDGERYSREGKGKGKERAKDREEVVFALGDDDEDDHH
The following text describes a protein:
Function:
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.
Sequence:
MWNKLQWIGLTYVVILIQESNASNADDDRDMWAWQAGWQWVWLAVAVVIGIAIFSRQRKTSQQADKESRQNKSTSPVDPQASLDVTSIKIFYGTQTGTAKNLAAQLAKDIPDTVNTDVIDLKEFDPEKHVLLDQDEQTVCVYILSTYTDGEPPEGGAWFCRWLHESVNDFRVPGTLLKGHQFAVFGLGNSLYQDHYNTVSKKVHQWLIDLSARPLLPVGEGNGNVAASKHGGTEADFAAWKSDFLQAVLKCDGSGDKSCSCNQNGTCQSSVIGQMSLEQNTVTPERDGGGEEKADDGLDSDQEDPDEMDVIDVEDLGSVMNKMKNAKAMNGVKLGTEPKEMVTPTIRKNLTKQGYRIIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMETTPSLACANKCVFCWRHHTNPVGTEWKWQMDDAESIVEGALKNHYNLIKQFKGVPGVKPERMKEAMKAQHCALSLVGEPIMYPKINRLVELLHKEQISTFLVTNAQFPDAIKNLLPVTQLYVSVDASTKESLKKVDRPLFRDFWPRFLESLKALSDKGQRTVYRLTLVKAWNDEEIQSYADLVQLGKPDFIEVKGVTYCGESKASTLTMQNIPWHEEVVHFVQKLMDLLPEYEIACEHEHSNCVLTANTKFKRDGEWWTWIDYSQFHALMAEYDASGGEKIFRAEDYMAKTPPWAVYGSKEQGFDPEETRFYRKGKKKDLGGC
The following text describes a protein:
Function:
Acts as an adapter protein that mediates cell signaling pathways involved in cellular functions such as cell adhesion and migration, tissue organization, and the regulation of the immune response. Plays a role in integrin-mediated cell adhesion through BCAR1-CRK-RAPGEF1 signaling and activation of the small GTPase RAP1. Promotes cell migration and invasion through the extracellular matrix. Required for marginal zone B-cell development and thymus-independent type 2 immune responses (By similarity). Mediates migration and adhesion of B cells in the splenic marginal zone via promoting hyperphosphorylation of NEDD9/CASL (By similarity). Plays a role in CXCL13-induced chemotaxis of B-cells (By similarity). Plays a role in the migration of olfactory sensory neurons (OSNs) into the forebrain and the innervation of the olfactory bulb by the OSN axons during development (By similarity). Required for the efficient tyrosine phosphorylation of BCAR1 in OSN axons (By similarity); [Isoform 1]: Important regulator of chemokine-induced, integrin-mediated T lymphocyte adhesion and migration, acting upstream of RAP1 (By similarity). Required for tissue-specific adhesion of T lymphocytes to peripheral tissues (By similarity). Required for basal and CXCL2 stimulated serine-threonine phosphorylation of NEDD9 (By similarity). May be involved in the regulation of T-cell receptor-mediated IL2 production through the activation of the JNK pathway in T-cells (By similarity); [Isoform 2]: May be involved in the BCAR1/CAS-mediated JNK activation pathway.
Subcellular Localization:
Cytoplasm. Cell membrane; Peripheral membrane protein. Cell projection, axon. Cell projection, ruffle membrane. Note=Associated with the membrane when EGF-stimulated (By similarity). Expressed at the cortical actin ring in B cells (By similarity); [Isoform 1]: Cell membrane; Peripheral membrane protein.
Domain:
The C-terminal Cdc25-homology/Ras-GEF domain adopts a closed conformation rendering it incapable of carrying out canonical exchange factor function, this closed conformation is required for interaction with BCAR1.
Sequence:
MTEGTKKTSKKFKFFKFKGFGSLSNLPRSFTLRRSSASISRQSHLEPDTFEATQDDMVTVPKSPPAYARSSDMYSHMGTMPRPSIKKAQNSQAARQAQEAGPKPNLVPGGVPDPPGLEAAKEVMVKATGPLEDTPAMEPNPSAVEVDPIRKPEVPTGDVEEERPPRDVHSERAAGEPEAGSDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGSSKPASPVSPSGPKGSHMKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAPEGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQARRYEKFDKVLTALSHKLEPAVRSSEL
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MDWLTILIIVIQCFIITLAVTTAFAYLTLFERRILARLQNRVGPNRAGPAGFLQPAADAVKLFFKEDIVPAMADKPVYLLAPALAVIPALIIWAVIPFGCLNLNWDYQACYDPARTNLWNILQITDLNIGVLYVLAVTSIGVYGITLAGWASNNKYSMLGGIRSSAQLISYELALGCAVLSVVMTYGTFSTHEIVAQQQGWLWGIIPQLLGFVLYMVAATAEVVRAPFDLVEAEQELTGGYNTEYGSMKFALFFMAEYIKLIAVSALAVTFFFGGWHFPGLDILGRGVTALAGPVAGSIVFGIVSLGAFLLKVVIFLFISVWIRASWPRLRYDRLMDLGWKWLLPVGLLNLVYTAVVIVLIPDRVVHSWVLFGLGALTIAIAIGFNRTPKPVDNVTLVNDIQIPQGN
The following text describes a protein:
Function:
Probable membrane-associated metalloprotease that may be involved in chloroplast development.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MASTSLVASLVCSSSTSSSTRRPPASRSFPLLSKNNYRPALSKPLRSSFILRSSLQEQDQEKKETNRPNSSIVVAPDEQKEDEEKKEPSHHTGGGDPEDHEGGGDDVENKSREEQQEVDWRSDEEFKRFMGNPSIEAAIKLEKQRADRKLRELDREPDASPVAALLRGFIRDTLQREKQRLEEAERTFKALDLNKLKSCFGYDTFFATDVRRFGDGGIFIGNLRKPIEEVRPKLEKKIAEAAGTEVTLWFMEERINDDMTKQVCMVQPKAEMELQLEVASLSTPWGYLSAVALAVTTFGTIALMSGFFLKPGASLDDYFSDVLPLFGGFLSIPGVSEVATRLTAARYGVKLSPSFLVPSNWTGCLGVMNNYESLLPSKKALFDIPVARTASAYLTSLVLAVSAFIADGSFNGGDNALTMQVYTAGVLLQQPAAVVRTAGDRAVRRRARQRAAQRRGGRWRAGGPSGIRRPPRDRRHVAEPAADRAARGRPDRAGALRPQHGGTAVVRHIAAAGRGRHQRQRAVPGLGALRHLHPGRGGDPGAGRDHAARQRALRVGLRARRRLPPHALPQWWRHLLQLLPRRALLQGRHLDLHHAMIIA
The following text describes a protein:
Function:
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built; Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MYGEKAIELIHELQRAVNGSLAPFNEEGVRQVLEEMKALYDQNQCDVEATVQGEKDRLPAVQFRHTCLERNKRCLLAYLHNRLCMIRDMRWEFGSVLPAEVKYNLSEQEVQWFTKYNKSLASYMRTLGQDGLDLTQDRSPPKSLYVEVRCLMDYGEFESEDGSSVVLKKNSQHFLLRSLCEPLIRQGVLEHIMS
The following text describes a protein:
Function:
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Domain:
Although it shares weak sequence similarity with GTF2B/TFIIB, displays a similar subdomain organization as GTF2B/TFIIB, with a N-terminal zinc finger, a connecting region (composed of B-reader and B-linker regions), followed by 2 cyclin folds. The RRN7-type zinc finger plays an essential postrecruitment role in Pol I transcription at a step preceding synthesis of the first 40 nucleotides (By similarity).
Sequence:
MDEQITGGYSEPCGQCAAVDWGVSDEGQFFCKSCHNVIEKIREVEDVTSLHHKHGRISIVRKPKKKKHDSEREWLVCEGFQFILKHQAKALVSLGVCMKFETEVLWNFWKRYLQNTRQAFTENPVSTARFEVFMKSQSGSESDTQSHQSCYSEASSDTEMSVSGISVDGRSAVSSESLHSIPQKGRRGRVSNLMSMPRTLAMCYLALLWVREAITLTDLLRMVAEGHIPYLHLHETFPAEMRMFGKDVQIFRVLFFPSYAFIKKEALVLAKIMKLPSFPTISQDCLFHPVPLTVRYLLEANLPDALHVWVQKVITGAGMDSDSFLTFDPTDKKPHLLSYDVQAVAVIIVAMKLLFKLDDHVEWKLSHDAAKKKNNKVFSLERWFNIVQPVLEQARLKEEQEEARRQWNFANPFITNLKRKSLVLKKRRVTDHLQQRFQKFADPAPEQSTSTTNSHTSFRFSWGEEEGSDGPSMFNQNLDCTVKAKAVNGLANQRYWHPELRICPENKCVSHFSKFEPSLPRMFVWVLDLFSFILGVLQSDVYEEVLNVERRFLKKNYRLDSRLTSSHLKKKKGPIL
The following text describes a protein:
Function:
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDH2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. Acts together with SDHAF3 (SDH7).
Miscellaneous:
MISCELLANEOUS: Present with 861 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MPKRLSGLQKEVLHLYRASIRTAHTKPKENQVNFVNYIHEEFGKYRNLPRKDFTTIEHLLRVGNKKIATFSHPELTNIH
The following text describes a protein:
Function:
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MGKKIKKGKEGPVKEYVSRTKALKKLQVNLKDFRRLCILKGIYPREPPQKLRKQHKTYYHNKDIAFLKNESILDTFRQRQAHLKKIRKALTRGDKLKAGRLRRNQPKDKLDHLVKERYPTFIDALNDLDDPLCLVSLFASFPTHKELHIPNTLIRSCQKLINQFFLYVSAHNCLRKVFLSIKGIYYQAVVQGATITWIMPYPIQASLPLDVDYKIMMTFLEFYQVLMKFVNFKLLGQEIEITDFSEEVMKLKSLAQNNQIEIDEAFKEDPTIQQMDQQQQETKKYSELFKGLTFFLFPEVPKSSLEFVILSFGGEVMWENDNKNSQLTDPKITHVITERTVQKNKKREYIQPQWVYDSINQLKLLSVADYAPESTLPPHLSPFEQLNLEEVQSESDEEDGQQKEHKPYQNNKKQKEKQAKQQEKETKKLAETMLSRKNKRLYDMIKRKEDEEQQKKNKLQEKKKMIQSKQQ
The following text describes a protein:
Function:
Cleaves internal linkages in 1,3-beta-glucan (Probable). Has a role in cell separation where it is required for the degradation of the primary septum after completion of cytokinesis.
Subcellular Localization:
Cell septum. Note=Localized in a ring-like structure around the septum.
Sequence:
MSSYLRSFIFGLLTISLAQCSPILKDTKDTKFSTGSNISLKKRDTNVFDSVVDTINPASYFGTVSHPVTPAGVSTDSLSSPIETNKFFDNNLLGSRTNFMYADPFRYWWQSSDTMGGICIAHTDDNQRVMDTDDTIPSYYYEPIGICSLGFGASGITSNTDPIVDEIDQMSARFTFSWDSSSMQLTLTEGMAVTTAVYTNAIPQIFSSTLYINDFVEVPGTSAVQKYRVTMSDNHVWLIYIYGDSLTLTESTSQMLVGSNTFNGYIQIAKIPLGDGTAEALYDTYAGVYITGISISGYVEDAVGYYSFDFTTAGDTSVEPLFFLLPHQVDTAVSGTKVTSIVLASLVSGDMNAAAGNSITFAEAIPQDIGFLPWSPTGGQIGYSEEALEIIAEVAGTELGEDFSANSNLNSMYYSGKVLAKYAMLCVTINDILGDETSSEQCIQKLEAAFARFVDNQQIYPLTYDNTWKGVVSVAGLSGDSLADFGNSYYNDHHFHYGYFVFTAAVIGHIDPDWINTGNNKEWVNFLVRDVANPSSNDPYFPKHRMIDIYHGHGWASGLFESNDGKDEESTSEDYNFFFGMKLWGQVIGDSDMEDRANIILGIERNALNKYMLYADGNVQPTSMQPNYVAGITFMNKITHTTYFGTNIEYIQGIHMLPITPISAFIRGPSFVLAEWNALLASVIDYVDSGWRSLLYANLAIAEPEESYEYFSSSDFNTDYLDDGASRAWYLAYAAGLWANDAVYYPVSSSSTTTTSTSTGSVTTTSTTATASCTLPISYTSTPTTTSISGTCNGATFDASLYVCDGTVLCPIVNGVSYQNCNGACYNPSQYGCDNGALGPVQSSSTTSSITPTPTTTSSITPTPTTTSTTTTAQSTGMQLCGSNYYDASSYYCDNDQLCPIIDGVDYLSCNGACYNPSQYVCSDGSLSPNTVTTTKATTTFTPTPTTTTTPTPTTTSATSTNVIAQCGSAWYDSQSYICYGNILCPIINGSPLLACGNACYDSSIYGCSNGALVAA
The following text describes a protein:
Function:
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Sequence:
MKKIFLSLADRSASNYVYEILKEGFEEYEIYGLTDEKLEKIGVKSVARYSEISTVGLIEALPKVFKFLKIYRKILKNLKNTDTLIACDAPALNLRLIKDARKLGVKRIIYFISPQVWAWKPKRAEIIANYCDHVIVILPFEKKIYRKFPNLKVHYVGHPLVDLVKPQKTKEEFMKAFKKEPLPLLLGSREGEIRRHVKLLKGIIEELKKSFDVISPTFREFSKFIERELKVKTLTYEGASYDCFFYSKASLIASGTASLEAGIAGNPHVVYYKVNPITYFLGKRLVKVPYISLVNILLKEEVVPEFIQKSSDEILKGFEKVYKNEEEIKEKLGTLKFILGERFVIRKLRELFLEIV
The following text describes a protein:
Function:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Note=Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
Sequence:
MQPRRAQAPGAQLLPALALLLLLLGAGPRGSSLANPVPAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDKILPRSQATVTLPTWQPKTGQKVVEMKWDQVEVIPDIACGNASSNSSAGGRLVSFEVPQNTSVKIRQDATASLILLWKVTATGFQQCSLIDGRSVTPLQASGGLVLLEEMLALGNNHFIGFVNDSVTKSIVALRLTLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGHMAESLTNMPRHSLYIIIGALCVAFILMLIILIVGICRISRIEYQGSSRPAYEEFYNCRSIDSEFSNAIASIRHARFGKKSRPAMYDVSPIAYEDYSPDDKPLVTLIKTKDL
The following text describes a protein:
Function:
Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
Subcellular Localization:
Nucleus.
Sequence:
MVDVFIPGAYCSKTFWPPSDKPPTSPIRLVRDGEQEIQQPFTTAHLEQPHTIRYINGHLGASPVSRANVTSSMDLLLKVLQPAINSDVMEMFHKYIEVFREGAENAAENMNLEPFKSVNRVVDVDALVSRACMNALENAKKIFRNKNSKQTKPTMDNWPPNLPPTIPSHVLPGKRRVASPDWTKRLKVGSSEASQRRSLSPIPKKRPRTNTPTAPMRSYGSPHRNTKEAIKRKVENWDPSRLNINAKFVMGTKANRALGLGATRGRIYMKHPDLFKYVGDHEDKKWMVKNNCMAATGGKNTFILLADDVMNLYDTEYKDSPGTMPEELQFFRLPEFVLQKMRSAMMREKKLRTGVKDVGSPVTETPQVASPHRNVRHAAQMAAAAISAALSPPGVSTTITTQCSTRTKISDTDSEDSYEDTGSMNL
The following text describes a protein:
Function:
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Sequence:
MPTILVSALEASSNAHLEELRQNLPEDYRFIGVFEGKEVLYSPREFSIMGFRDVIGRLGFLLKAHKEMVQLAKQADMVLLMDSSSFNIPLAKKIKKQDPHKKIMYYILPQVWAWKKWRAKSLEKYCDFLGAILPFEVGYYQKKAQYVGHPLLDEIKHYKKDIKGETLVFMPGSRKSEIAKMFPLFVKAAQMLEQNEGFKRRVLVVPSFFKGLDLKALYGEDIQLFEISYDAHKSLFEAEFAFICSGTATLEAALIGTPFVLAYRAKTMDFLIARMLVNLHYIGLANIFYNALNNETPGLGESQLHPELIQHFLSVEGLLKAYKEMDRERYFKESLRLREYLKHGSARKIANEMAFLLNLT
The following text describes a protein:
Function:
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Subcellular Localization:
Nucleus.
Sequence:
MEEDKVFTFRDVKPTPDIYHTYDSSLKGNNAPPIVLDHGSYQCRVGWAVDPNPRLTFRNLMAKLRKEKGKSDVEILVGNDIANFEAVRFQLKSPFDRDVITQIDTVETVFDYAFSHLGIDTEGSINHPVVLTEAVCNPSPARQFMNELLFECYQVPAVSVGIDALFSLQHNFSKPCVELPTSLVVRLGYQTTHILPVIGGKCDPQGIRRINLGGLQMISYLHRLLQLKYPSHLSSATFSRAEELIHDYGYIAEDYLKELSKWADGDFYEENVRKIQLPFIPAPTAAETSLNLEQQQQRRKENVKRLVEINAKKREERLASDEERLETLQIIQHQLAEVDDGLAVKLLRQAEITDEHHLEQEIQNIQDRVSRTRQKMAAAAVNPNEEGEPKKPTETAEFQEWLEGIRKQRTEILSRRRERQQRRQELTKRKSAAAQERMRILSMLAKSGSSGPGKKKEDTFGMKDEDWDIYKAVSKDGGGSDSEAEQEKLNDLESALKRYDPNFKNYSGASSSTGEGSSGGFIPTAEYYQLHIGTERIRAPELFFQPSFIGSHQAGISETIDYVVKLYDPATQLQLVSNVFVTGGCANIPGLVPRLQKDLLSMRPFESPFNVNIAADPAGDSWKGAREFGKVAPPSAYLSRSEYQECGPYYFTEHHASNKRFALMKQ
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEPVTFEDVAVNFTLGEWALLDSYQKELYRDVMKETFSNLISIGKTEEENIEDYQNIRRNLSTHVVEGFYEFERGIQYKETHQHIQEHAVHKYMPPGIVVYENIACENGVIDLSQSDVHPRVLTVEKSDERQKCTEKPVQHKKCWKDFVYSESFLTHEKPSREKPYGNEQFNDPCGSLTSYQGYETTHNGDNLREYKQLETALMTCSYVQSYERIQSGDKPFVCKQCGEAFVNSSHLIKHYKIHTREKTFACKYCGKAFIHPRACYNHERTHTGDRPYVCKQCGKACIHSYHLLQHERSHTREKLYACKQCGKVFGRSSYLRKHERIHTGEKPYLCKHCGKAFSDPTTRNNHERTHTGEKHYVCKQCGKAFIRSSQLLIHERIHTGEKPYSCKHCGKAFTYSSACYIHERIHTGEKPYVCKQCGKAFTCSTYLHKHERIHTGEKPYSCKQCGKAFIQHRACYNHERIHTGEKPYVCVQCGHAFTFSKSLQIHERNHTGEKPYVCKQCGKAFTCSTYLHQHERTHSEKKSNG
The following text describes a protein:
Function:
Involved in cytokinin biosynthesis. Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP.
Sequence:
MECKGVNGQSPKPKVVFVLGATATGKSKLAISLARRFGGEVINSDKIQVYDGVPILTNKVTEEESAGVPHHLLGGVHPDADFTADDFRRVAEAAISRVISAGRLPVVAGGSNNYVEALVEADGAAFRAAHDCLFLWLDAAPGLMEWYTGLRVDDMVRRGLVDETRAAFEEGADYTRGVRRAIGLPEMHEYLRAEREGAVGAAEMAALLERAVREIKANTFGLVLQQAAKIRRLSTLEGWDVRRVDATAVFASMAEGSGGHKEVWESAVWAPCQEMVRLFLHAEAATLPTDLEVDEAMAGLSLGVSVIPVAAVGDVGDDDVSVVLTPPTVLHEHENEGSINKDGAAGVVLNGTHDVVDKDPACGGGDGEDHGSNAGVAQAAPAAAGAKPDDTA
The following text describes a protein:
Function:
May play an important role in the response of cells to diverse environmental stresses.
Miscellaneous:
MISCELLANEOUS: Present with 784 molecules/cell in log phase SD medium.
Sequence:
MKVSQVFISAISVFGLATSVNAQNASNTTSNAAPALHAQNGQLLNAGVVGAAVGGALAFLI
The following text describes a protein:
Function:
Negatively regulates lifespan and health span probably by participating in nutrient sensing.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MHSEEKYLHIPNNTKYPEIIVEEEEEDPSEEERSELSETDDVATPLRPSDTFPFKRRNSPCSIKMSEEHLKRLREIACPSPTPTQCSTVSKHEFQNWRINEDVMKDMMHIGTICERENVCKTSKYVYTATMASYTVTEWKLKEGNTPDEIEKISRTIEDLCQLRHKRLAPMYGYHWRLETELMVFRAHVPSGTVADLVKVSAIPQETAVRYIVHVIDALAYLHERKHVHGKLNASNLLLTISNDILLADPFIEGLPSAQKRRALLASPPEAFRSLESYPCLTPSSDIWSVGCVLVTMLTRYPPFLEHYMHFHGESLHRELVSEWCTRRQLIYSSQTLIPSASKEICELIDQIFNVDPENRPSAQNLLESHGSKSRKASLRNSLASLTTAKEPDPPKPIDDFYVEREDDEEHRKIEELRELAERGNNEGGFIPFIRWYMSRILIFSVLLVKWIGMVLCAALSLAAVAGGVFFAIFLIYNGIQIACQCSLNEGFVVLIALILLPIIILLTTLCCNNSLDRYHADVESGKVEKSRFVMKTPEKDVIVGGYILVEGSPDHDKPAEVPRKLGISEGLQSTMGNTFLGYGVDKIA
The following text describes a protein:
Function:
Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.
Sequence:
MSDGPTENSSVHPRLLQPHLSVYLGAFFHPSTTSRSCSTVVPVAQRFQARVSFRLFHSIFVSYRPRLLPSVWWSCTFPSVRPDKTSLTPPDLKRFLASFPFPADIVKNPCTSSRSHPVHPVLPPRAQGRSRAERADWNIVDLADAPPFHSPSSAAADLPNASIPSDPILSRPNAGSPVDSIPPSPQRDTLSSDRRSGLAERSSASTRRRRHSPSDTLDSYTYGTGGRAGGHTAASEISSQDQPSQFGPSVEGHPPFSKRRRLANMRPDGISSTNNFSQLSKGGAASPAQKAALSRALNGQASYSGSNGEMKVDGFQKPSKTSSYFNHDREEVTRILIQSLYELGYSNSAALLSKESGYQLESPAVAIFRNAVLEGRWAEAERILVQSFQEQGQEETASKEKLALVENAEKSEMLFYLRQQKFLELLDARDLGAALMVLRHELTPLNYDVGRLHALSSTPVYLCVLRNIFMTKPAGTVPSASRGKDCYLSCQSPSLYSDHMCDRDDFPLGTKLELNKHTDEVWHCQFSHDGTKLVTAGRDSNVIIYDTSTFSVLYILGEHKNGVAHAVWSPDDTKLITCSRDSTARVWSTETGRCLLTINKHQEPVTAAVWAPDGESFVTASLDVNSQLCHWNMRGESLYMWHGGFRVYDCAITPDGRRLIAVDVERKIRVYNFHTHEEEYILPLKSKATSVVVSRDSRHMLVNLTECQIQLIDIETSEVIRRFQGQKQSTFIIRSTFGGAAENFVVSGSEENGTLVETLEGHLEGCVNAISWNPADPGMFASAGDDCLVKIWTRERDAHPNSVPGKRRAVSGNGYARTSALRSTSGF
The following text describes a protein:
Function:
Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision.
Sequence:
MQHELQPDSLVDLKFIMADTGFGKTFIYDRIKSGDLPKAKVIHGRARWLYRDHCEFKNKLLSRANG
The following text describes a protein:
Function:
Probably involved in the defense reaction of plants against pathogens.
Sequence:
MIGFSKHSSAMICLVALFIMIMPSSCRSCFPRPPPPPSPLLPPPPPPPSPLLLQSPPPPLSSSPPPPLPSSPPPPSLPSSPPPPLPSSPPPPLLLSPPPPSPSPLPPPPEDDPLEIQNYLDSHNTARAEVGVGPMEWNNAVYTYAQGYANQRKSDCLLQHSETSYGENLFWGMGKEFTAVDAVKAWVDEKQWYHYEDNSCDSGKMCGHYTQVVWSNSVELGCARVQCANGAYFITCNYNPPGNYVNQKPY
The following text describes a protein:
Function:
May be involved in DNA replication and thus regulate cell proliferation.
Subcellular Localization:
Nucleus.
Sequence:
MLWVDKYRPKSLDKVIVHEDIAQNLKKLVTEQDCPHLLFYGPSGSGKKTLIMALLKQIYGASAEKVKVENRAWKVDAGSRTIDLELTTLSSTNHVELTPSDAGFQDRYIVQEIIKEMAKNRPIDTKGKKGYKVLVLNEVDKLSREAQHSLRRTMEKYSSSCRLILCCNSSSKVTEAIKSRCLNVRINAPSQEEIVKVLEFVAKKESLQLPHGFAVRIAEKSNRSLRRAILSLETCRVQNYPFTDNQVISPMDWEEYVAEISTDMLREQSPKSLFQVRGKVYELLVNCIPPEVLLKRLLHELLRKLDSELKLEVCHWAAYYEHRMRLGQKAIFHIEAFVAKFMSIYKNFLISTFG