lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a role in the cellular breakdown of insulin, APP peptides, IAPP peptides, natriuretic peptides, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. Substrate binding induces important conformation changes, making it possible to bind and degrade larger substrates, such as insulin (By similarity). Contributes to the regulation of peptide hormone signaling cascades and regulation of blood glucose homeostasis via its role in the degradation of insulin, glucagon and IAPP (By similarity). Plays a role in the degradation and clearance of APP-derived amyloidogenic peptides that are secreted by neurons and microglia. Degrades the natriuretic peptides ANP, BNP and CNP, inactivating their ability to raise intracellular cGMP (By similarity). Also degrades an aberrant frameshifted 40-residue form of NPPA (fsNPPA) which is associated with familial atrial fibrillation in heterozygous patients (By similarity). Involved in antigen processing. Produces both the N terminus and the C terminus of MAGEA3-derived antigenic peptide (EVDPIGHLY) that is presented to cytotoxic T lymphocytes by MHC class I.
Miscellaneous:
MISCELLANEOUS: ATP-binding induces a conformation change.
Subcellular Localization:
Cytoplasm, cytosol. Cell membrane. Secreted.
Domain:
The SlyX motif may be involved in the non-conventional secretion of the protein.
Sequence:
MRNGLVWLLHPALPSTLHSILGARPPPVKRLCGFPKQIYSTMNNPAIQRIEDHIVKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIPGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDASCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVREELLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQQYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGKLHYYPLNGVLTAEYLLEEFRPDLIDMVLDKLRPENVRVAIVSKSFEGKTDRTEQWYGTQYKQEAIPEDVIQKWQNADLNGKFKLPTKNEFIPTNFEILALEKDATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKITEKMATFEIDKKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGVMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQRRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKAIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNYDRDNIEVAYLKTLSKDDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPSQNDINLSEAPPLPQPEVIHNMTEFKRGLPLFPLVKPHINFMAAKL
The following text describes a protein:
Function:
Essential for normal male fertility and for progressive motility of spermatozoa.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MSASLKRITAFARVKPTSDFPQDVLKFRADNKTIDVFVERDVSKGVVNNKQTNWSFKLDGVLHNASQDMVYNVLATGLVSQALNGYNGTIMCYGQTGAGKTYTMTGMTESYLNRGIIPRAIQQVFKSVEEHGSQFITVRISYMEIYNETIFDLLSMMPLGAAMDVPLSVVESPYGVSVKGLTIHPAPTEEVALNLLFEGNLNRSVGQHALNTRSSRSHCIFTIYIECHSRILSDARYVTSKINLVDLAGSERLAKSKSEGQGLKEATYINKSLSFLEQVILALSDRNREHIPFRQSKLTYTLKDSLGGNCNTVLVANICSEAIHIIETLSTLRFASRMKWVMTEPIVNEKFDAERMVKNLEKDVLYLKEELAMHNSLVRRGLGWPGQAELRLGLVTMQVKHQEEMLLEHVGHTAQKLHNNACFSPSLPFCQAGLVDAEGHLVGEVDGQGFGIGVAPFSSKPGGKKSKAKKGKDLSSPTSKKEGPVSPQSGKEVEPVSPSRSQVTTSGKEPEVKETRELDTISVDTHRSDSAAKEEASTRPSSPPARPAAFEDFKNERGSEINRIFKENKGILNDRKKKLSEVAHRLNLLKQEMDTARQALEAQKLEREQQGEYLNDEGQIIIDEEEFLLIMKLKDLRKQYRADYSELRDLRSEVQYCQHLVDQCRNRLLTEFDIWYNESFLIPEEVQEVLRPGGAIRLGMIPINRVLTLVSNSSSLVGRLPTISCRRLICCSVVTAKRFLQSIFQGSGHHVSACSSKTDVATSN
The following text describes a protein:
Function:
May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MCDNQVITLDMGLLVAGTKYRGEFEERLKKLMEEIKQSDEIILFIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYRKHIEKDPALERRFQPVKVPEPTVDETIQILKGLRERYEIHHKLRYTDEAVVAAAQLSHQYISDRFLPDKAIDLIDEAGSRVRLQHAQLPEEARELEKELRQITKEKNEAVRGQDFEKVCSFLSNLCIKFHGSGQAGELRDREMDLKAQISTLIDKNKEMSKAEAEAGDAGPVVTEADIQHIVSSWTGIPVEKVSTDESDRLLKMEETLHTRVIGQDEAVKAISRAIRRARVGLKNPNRPIASFIFSGPTGVGKSELAKSLAAYYFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGYTEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMMLQILEDGRLTDSKGRTVDFKNTLLIMTSNVGSSVIEKGGRRIGFDLDYDEKDSSYNRIKSLVTEELKQYFRPEFLNRLDEMIVFRQLTKLEVKEIADIMLKEVFVRLKNKEIELQVTERFRDRVVEEGYNPSYGARPLRRAIMRLLEDSMAEKMLAGEIKEGDSVIVDVDSDGNVTVLNGSTSAPSDPAPEPIPV
The following text describes a protein:
Function:
Involved in endocytosis.
Sequence:
MAGKVAKGTNRIENDIFKCRDEANWRKIQDLAEQLQQRGGGPASGRFFIGESKLEQFLEEHPPTEVNIPKAKTGLTEAKRYLQHCFTEHGAKACRLTMPFIYYISRLLSKLLYAQGFYEEALTHLDSGGIDRLDEKSLSNRILKILAESFAIKGLCLEKVPLKSTSRTRAANRDDQIAGYFVQASDLALKYLQEVEKAQGTIGGVLPMATTAGAQAAVASSSSPLPPNTEYRIGAVLETVLQRAPLLMIKSGKLRQAIDQYRNVLRAEETSSTQSLRQTMSRQLAEVLLRGLSESVYNDYEPRIETKKQGKHWRPNKYTGQSLFMPKTEYEEVLLLLFISESMAVRNAVLDRSPEFLDARIHSYNNVTAVYDLLAIILSRLGQFQILCESFERAMKFAFEEYHVWMQFSLALLSSGKFSRACLMLKECARLQPHNSFPCLLAAKVCLEHLGSVEEGVEFAEEALSREKQHSQSLLAQCHLVLGVGHALMADQRRPQSRRAEHKATAFQCFLRAQSADPYYHLPEFHLALHYAEVRQVRNYLPRLSDPLAAAKFSSFTVASYIGFSRKAPRSQHAARQACPGAEPRAPAKQHSEALQLVTATLEEYPDCLNLMYTKAHLEDYCLGPEEALLTSKQMLLQWKAYYEAELKRVTSCNRGSFHVRSADFSDRESGTTSCHSIAAAARVEQALSEALSPGGTGAVVGAGHHGGGGTEAGRNRRGPQALWLLQLQVWLLIAELYLKMEQLSEAEACILEASNIYPLSHQLMVLKGLLHEKRKEYLDAKQCFQNAVSINPLHVTALQHLGLVYHYLGSSQLAEKTLRDAVAIDPMCHQSWFNMGKVLQETGDFDSATDCLNTAIQLEMTTPILPFSVVPHSLE
The following text describes a protein:
Function:
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
Subcellular Localization:
Secreted.
Sequence:
MKFLALAALFASTVSSIAVDGLIPGARVIPANDVVALKKVGAHHQKHPHRRTVIIRPSFNDEDDVSADFLWGIKWANRGGRLLLQKGKKYVIGKKLDLTFLKDIEVQLDGELKFTNDVPYWQANNFYYDFQKSISFWRWGGEDIKIFGSGVLNGNGQRWYNEFAGQEILDPNNKYYRPILFVTENATRVSVEGITQLNSPCWTNFFVRTKDISFNNVFIHAYSTNASALPKNTDGFDTLNVDGLTVTNTRVDIGDDCLSPKPNTTNVFVQNLWCNGTHGTSMGSIGQYPGVLDIIENVWIENVTLLNGENGARLKAWAGPNVGYGRINNVTYKNIHVENTDNPIVLDQCYFNINATQCAAYPSRVNFTNIVFENIYGTSSGKHGKVVADLTCSPNAVCSGIRLKNIHLTSPAGSPPVIVCDGIQGDIGVECQSSTNLTTKRSIGLARNLKYKA
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MLRTGATVEAKNKVVLRSDAIPQKANPVDESKKDTKPQSTPTTSVPANRNGVSSGVASGVGRAKEKEKVAAGDKNKRILTPNTGKGKEQSMIADEKGVMKRKIGGEQDHARVPARKSRTNPVIKDAPRHEKGYDELADDEFHCSICMETKQLNESFSVSSCSHIFCTSCISQYVAAKVEENVTVISCPDPRCKNGILEPDMCKLILPEGVFHRWGIGLCESALGTQKFYCPFKECSALLVHDGADTDKQLITNSECPHCHRMFCAQCKVPWHAGICCKGFQELGKDERTREDILMRKLATDSKWQRCPQCRIYVEKIDGCMFMMCRCGYCFCYVCASPMTKELHYCAKCQR
The following text describes a protein:
Function:
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.
Sequence:
MRRNATTSSSIQQPDCCQPCPSLPTTATSRLDHRTSRYRTRYSIPTSFIPYQPTQVVLHTQQCSSRDTRRSKGAIHPHRNNSREATHRSSKCSNSRAAILHSNSSGYPPQQQHQQQGGYPPQQQHPPTQQQQPMPQQPMMQHQQQPMPMQPAMTPVHAAQPVAMVGGGGPPIVLAAGEQWMLVPVVPMGLTIPPGLEYLLPCAGAHVRQKTDIVEVLTDIDTPNKYCIYNDQGQFKQGLGGFVEAQLIGDSRGFYIVATDGMGRPSFAIARSSKLWTDAEMRVEAPPGVPAAYVVYNSSLCSRGGLTIFDVNHAPVLTIPFPSECDCNADRAYPVLSGGAAVGSVTRKYPGFMKSAFTTCDNFACVFPADLDVRIKAALLGCAIMIDFIDYEDKRK
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Sequence:
MSTTHRPTFTAAKGRESNAHLSQQRSVLSIPQHTKLKLRRPALSSAEGVAATHAAGTRRDLKRELEHAEWSAKNKKRINDGLPPLALPHSSPTVQDEQRTSAIEQAIQLELDRSSASEESHAHSSSESDDESSDSPSASDEQHALLLELQKIKSERAAQHAALHRQADASASISRDHELAHANPLLNLHHALDASASTPTSDTSPHFTIHNRWDHDVIFKNQATTSTNAHSAPSFINDLTRSDFHKKFMNRYIK
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome.
Sequence:
MSFMSLMANTAHQLWYPTSFPSMKELEKEEVRLETQELAIKQFGFRTIRPIGLNRSMQEQLDLEEQEREEANQDTELDEEELGSGSFPEEGEMDDMDGDNEEVEDHDIEEVDLDADITNADASEFYEDISEYGFQN
The following text describes a protein:
Function:
Regulatory subunit of anion-selective CLCNKA:BSND and CLCNKB:BSND heteromeric channels involved in basolateral chloride conductance along the nephron to achieve urine concentration and maintain systemic acid-base homeostasis, and in the stria vascularis of the inner ear to establish the endocochlear potential necessary for normal hearing. Most likely acts as a chaperone that allosterically regulates proper sorting of CLCNKA:BSND and CLCNKB:BSND channels at the basolateral plasma membrane domain and functional switch to ion conducting state. Mediates constitutive opening of channel common gates.
Subcellular Localization:
Basolateral cell membrane; Multi-pass membrane protein. Note=Staining in membranes of the renal tubule is basolateral. Also detected in basolateral membranes of intercalated cells of the collecting duct, which are known to express CLCNKB as well. Both acid-secreting alpha-intercalated cells and base-secreting beta-intercalated cells express this protein basolaterally, but intervening AQP2-expressing principal cells appear devoid of protein expression. In the inner ear, colocalizes with CLCNK in K(+)-secreting marginal cells of the stria vascularis. The basolateral staining contrasts with the apical localization of the KCNQ1 K(+) channel. Also found in K(+)-secreting vestibular dark cells, where it colocalized in basolateral membranes with CLCNK below apical membranes that expressed KCNQ1.
Sequence:
MADEKTFRIGFIVLGLFLLSLGTFLMSHDRPQVYGTFYAMGSVMVIGGVIWSMCQCYPKITFVPADSDFQGILSPKALSLLETGLSEVKSPQPPYVRLWEEAAYDQSLPDFTHIQMKVMGYSEDPRPLLAPELKTGASSVREGEPRTAQAWMEAPVVVHRGSDENEGEKSHSQSSPSVGPQGSAPLASFHDDLDVGSSEGSSLQPSPNRDEPHRQVPWASRGPLDRFSDFALIDDTPTSEDTVLDGQAREAALPRKQQWSLRMKGETVQARAEEPEQEEEDLYYGLPDSPGNPLPDKELGFEPDIQG
The following text describes a protein:
Function:
Involved in the biosynthesis of jasmonic acid, a growth regulator that is implicated also as a signaling molecule in plant defense. Converts 13-hydroperoxylinolenic acid to 12,13-epoxylinolenic acid.
Sequence:
MNQSGMARSDEGSLVPREVPGSYGLPFVSAIRDRLDFYYFQGQDKYFESRVEKYGSTVVRINVPPGPFMARDPRVVAVLDAKSFPVLFDVTKVEKKNLFTGTYMPSTSLTGGFRVCSYLDPSEPTHTKVKQLLFSLLASRKDAFIPAFRSHFSSLLATVESQLLLSGKSNFNTLNDATSFEFIGDAYFGVLPSASDLGTTGPAKAAKWLIFQLHPLVTLGLPMILEEPLLHTVHLPPFLVSGDYKALYKYFFAAATKALDTAEGLGLKRDEACHNLLFATVFNSYGGLKVLLPGILARIADSGEKFHKKLVTEIRAAVAEAGGKVTIEALEKMELTKSAVWEALRLDPPVKFQYGRAKADMNIESHDAVFAVKKGEMLFGYQPCATKDPRVFGPTAREFVGDRFVGKEGSKLLKYVYWSNGRETESPSVHNKQCPGKNLVVLVGRLLVVELFLRYDTFTAKVGLDLLGTKVEFTGVTKATSGVADAV
The following text describes a protein:
Function:
Damages membranes of susceptible bacteria. Has no hemolytic activity. Not toxic to mice. Does not inhibit the proteinases elastase and cathepsin G.
Sequence:
MERFTKNCRGFQKREEPQETFLLFSPPEFCHLPKDSGPCEAYMPRYFYNPKSNKCEKFIYGGCRGNQNNFKTFKSCHYTCVEKPGTCPRPPPGTITICPVRCQSDWACPGKEKCCRYVCMVDCMAPK
The following text describes a protein:
Function:
Positive regulator, may be partially responsible for expression of neighboring gene dlsT (yhaO) (By similarity).
Sequence:
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFNGK
The following text describes a protein:
Function:
Component of the transition zone in primary cilia. Required for ciliogenesis.
Subcellular Localization:
Cell projection, cilium. Membrane; Multi-pass membrane protein.
Sequence:
MGKKQVVSEPQRPPRALPPVPSAIQDEIPLSHPKKKKSRTKSTPAPASSEGLAEPVVNRRAEGSEPPAAELKEYPEAPVQRKQKKIRPPPELETSFTEKPSSPSLLRNENGMDVEPREEVVIPKPRRKAKKMQPAEPQYASELGVEDEDVITDEQSTLEHHSRFTAPTGVSQPVGKIFVEKSRRFQAADRSELIKTTENVDVSMDMKPSWTTRDVALSVHRAFRMIGLFSHGFLAGCAVWNIVVICVLAGDQFSNVSNLLQQYKPLAYPFQSLLYLLLALSTVSAFDRIDFAKTSVAIRNFLALEPTALASFLYFTALTLSLSQQMTSDRIYLYEPSVNGSLWPAEVEEPVLMPWVIVNLVVALLVGLAWLFLSYRPGMDLSEELMFFSDVDEYPERGVKASP
The following text describes a protein:
Function:
Alanine racemase, part of the diffuse TOX2 gene cluster that mediates the biosynthesis of the HC-toxin, cyclic tetrapeptide of structure cyclo(D-Pro-L-Ala-D-Ala-L-Aeo), where Aeo stands for 2-amino-9,10-epoxi-8-oxodecanoic acid. HC-toxin is a determinant of specificity and virulence in the interaction between the producing fungus and its host, maize. TOXG catalyzes the conversion of L-alanine into D-alanine, an essential precursor for the production of the major forms of HC-toxin by the non-ribosomal peptide synthetase HTS1.
Miscellaneous:
MISCELLANEOUS: The genes involved in HC-toxin biosynthesis, called collectively TOX2, are organized into a diffuse cluster that spans >500 kb. All of the known genes are duplicated or triplicated within this region, with some variation in copy number and chromosomal location among different race 1 strains.
Sequence:
MSNMVLNGNIDKSDRNSILDILQSLENIAWGQPGSARCDFRSDVITRPSLRMLSAVLKTTLGDDVFREDLTTAHFEAHVAEISGREEGMFVITGTMANQLCLHALVSTRPCGILLSSESHAIHYEAGGSSMLSGAMLQPVQPSNGKYLRVEDLEEHAILTDDVHKCPTSIVSMENTAGGAVVPVHELRRIRDWAKQNNVRTHLDGARLFEAVATGAGTLKEYCSLIDLVSVDFSKNLGAPMGAMILGDKKLIQQMRRTRKGIGGGMRQGGVITAAAREALFENFGLGAEIESQTLLQVHKVAKRLGEEWTRKGGKLSKEIETNIIWLDLDAVGIKKSQFIDKGREYGVILDGCRIVCHHQIDIYAVEALIDVFHDILKADPIKNKNSDR
The following text describes a protein:
Function:
Alpha-amylase inhibitor.
Subcellular Localization:
Secreted.
Sequence:
SGPWMCYPGQAFQVPALPACRPLLRLQCNGSQVPEAVLRDCCQQLAHISEWCRCGALYSMLDSMYKEHGAQEGQAGTGAFPRCRREVVKLTAASITAVCRLPIVVDASGDGAYVCKDVAAYPDA
The following text describes a protein:
Function:
Putative odorant or sperm cell receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKYEEMEAEKNVTTVMQFVLQGFSDLPNLQGLLFAVFSITYVIILIGNRLIIVITRLDATLQKPMYFFLANFSSLEICYVSVTLLRILVNICTQDRSISMLACASHMCFFLILGATECFFLAVMAYDYYVVISNPLHYSLVMNHKICIQLAVGSWISGIPMQIGQTCQIFSLHFCHSNQINHFFCDIPPILNLACGDTSVHNLPVYVVALLFVSGPFMLVLGSYSKIISTILRFPIARGQTKAFSTCSSHLLFVFLFFVSATITYLRPKSSHSAGIDKLLSLFYTTMTPMFNPMICSLRNKDVIAAFRKVLLNKYLMNLFINVLRYFFFLKKLCVYLGPHPQHMEVFRPGVELELQMLSYDAAMAMPDLSCICDLHHMSGQHLILKPLSNAKDQTCILMDTRHILNSLSHNKKSLRYF
The following text describes a protein:
Function:
Cytokine which binds to interferon gamma receptor 1 (ifngr1). Also binds with lower affinity to interferon gamma receptor 1-like (ifngr1l). Has activating effects on macrophages and neutrophils (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MMVSTARAVVCLSLCLCVCQVRGSHIPARMNKTIQNLLQHYNISNKDRFNGKPVFPKEPLSGRMETKMLFMGGVLETYEKLIGQMLEQLPNTTPPTAGSREGLNSAAPEVSVRTDLNYILKKVQELRTNRFKEQSKLLQGLHDLGDIKMNNFIIQSKALWELQWMYEEASSLSNNTKMQRRRRRRRRQARKVKTPTRA
The following text describes a protein:
Function:
Ring-cleavage dioxygenase that acts specifically on gallate to produce the keto-tautomer of 4-oxalomesaconate. Mediates the first step of gallate degradation pathway.
Sequence:
MADEGGNPRDLPPVGGHAALSRHIGQSLMADEFDMSFFRDKPLDHGFFSPMSALLPCDESWPVQIVPLQVGVLQLPIPTARRCYKLGQALRRAIESYPEDLKVAIVATGGVSHQVHGERCGFNNPEWDAQFLDLLVNDPQRLTEMTLAEYATLGGMEGAEVITWLIMRGTLSANVERKHQSYYLPSMTGIATLLLENRDQALPAPVNERHRQHMQHQLAGAEQLEGTYPYTLERSAKGYRLNKFLHRMIEPQWRQRFLSEPEALYREAGLSEEESDLLRRRDWRGLIHYGVIFFVLEKLGAVLGVSNLDIYAAMRGQSIEDFMKTRNQQVRYSVAGKAPN
The following text describes a protein:
Function:
Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites. Not essential for ubiquinone synthesis.
Miscellaneous:
MISCELLANEOUS: Present with 861 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MRKLNPALEFRDFIQVLKDEDDLIEITEEIDPNLEVGAIMRKAYESHLPAPLFKNLKGASKDLFSILGCPAGLRSKEKGDHGRIAHHLGLDPKTTIKEIIDYLLECKEKEPLPPITVPVSSAPCKTHILSEEKIHLQSLPTPYLHVSDGGKYLQTYGMWILQTPDKKWTNWSIARGMVVDDKHITGLVIKPQHIRQIADSWAAIGKANEIPFALCFGVPPAAILVSSMPIPEGVSESDYVGAILGESVPVVKCETNDLMVPATSEMVFEGTLSLTDTHLEGPFGEMHGYVFKSQGHPCPLYTVKAMSYRDNAILPVSNPGLCTDETHTLIGSLVATEAKELAIESGLPILDAFMPYEAQALWLILKVDLKGLQALKTTPEEFCKKVGDIYFRTKVGFIVHEIILVADDIDIFNFKEVIWAYVTRHTPVADQMAFDDVTSFPLAPFVSQSSRSKTMKGGKCVTNCIFRQQYERSFDYITCNFEKGYPKGLVDKVNENWKRYGYK
The following text describes a protein:
Function:
Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA. Plays a role in replication-dependent histone mRNA degradation (By similarity).
Subcellular Localization:
Cytoplasm. Note=Discrete foci at the inner surface of the cell membrane.
Sequence:
MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKEKITFKYDIEKIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYIAILPELGGYINESGHLNLPRFERYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGAAAEEAKNCKEKRKPKGQENSLSWAALDKSEGEGVASRDNFEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDEFLANQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIRSISTLKIHFELGKPFKPFEQLLAVLPSASKNLLPTCYQHLMTSEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDETRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFTYSSPWPEKFPAIERCCTRYKMISLDAWRVDINKNKITRVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENLMLEISVNAEPDELRIENIASAVLGKAVFVNWPHLEEARVVAVSDGETKFYIEEPPGTQKVYLGKTAPPSKVIQLTDKEQSNWTKEIQGISEQYLRRKGIIINETSAVVYAQLLTGRKYQISQNGEVRLEKQWSKQILPFVYQTIVKDIRAFDSRFSNIKTLDDLFPPRTMVFMLGTPYYGCTGEVQDSGDLITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLAGRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAAEQLLAEYIERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLHILDAAIVEKIEEEVEKCKQRKSNKKVRVTVKPHLMYRPLEQQHGVIPDRDAEFRLFDRVVNVRESFSVPVGLRGTVIGIKGASREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRCETGNQKLTAIVKPQPSVSHCSAAPSGHLGGLNHSPQSPFLPTQVPTKGDDEFCNIWQSLQGAGKTQHLQPTVQEKGAVLPQEISQVTEGHKSGFTDHSVRHQQRKHDSQRKFKEEYKSPKAECQSQKLSSKQTSGGSARCSIKLLKRNESPGTSEAQKVVTSYPNAVHKPPSGIENFLASLNLSKENEAQLPHHGEPPDEADLSPQSFAMKGTRMLKEILKIDSPDTRDSKNDMKKSDNEATVSSRRDERGVSAHPKPTCHMNKPHGTNEFQNVASVDSVCWPGQMPPVSTPVTELSRICSLVGMPQPDFSFLRTTQTMTVCQVKLSNGLLVHGPQCHSESEAKERAALFALQQLGSLGVSFPLPPPIFTNYPPAVPPGAVPPVFTQPTANIMPSSSHLFGSVSWRPPVPVAGNAFHYPSYPGTMPLAGGVPGGVHSQFIPLQVTKKRVANRKNFENKEAQSSQATPLQTNKPGSSEATKMTPQESPPASSSSSQAAQPVSSHVETASQGHVGSQPRSAPSSSKRKSRKLAVNFSVSKPSE
The following text describes a protein:
Function:
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Required for mitotic division septum formation during adverse conditions.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSDQNNRSRNEYHSNRKNEPSYELQNAHSGLFHSSNEELTNRNQRYTNQNASMGSFTPVQSLQFPEQSQQTNMLYNGDDGNNNTINDNERDIYGGFVNHHRQRPPPATAEYNDVFNTNSQQLPSEHQYNNVPSYPLPSINVIQTTPELIHNGSQTMATPIERPFFNENDYYYNNRNSRTSPSIASSSDGYADQEARPILEQPNNNMNSGNIPQYHDQPFGYNNGYHGLQAKDYYDDPEGGYIDQRGDDYQINSYLGRNGEMVDPYDYENSLRHMTPMERREYLHDDSRPVNDGKEELDSVKSGYSHRDLGEYDKDDFSRDDEYDDLNTIDKLQFQANGVPASSSVSSIGSKESDIIVSNDNLTANRALKRSGTEIRKFKLWNGNFVFDSPISKTLLDQYATTTENANTLPNEFKFMRYQAVTCEPNQLAEKNFTVRQLKYLTPRETELMLVVTMYNEDHILLGRTLKGIMDNVKYMVKKKNSSTWGPDAWKKIVVCIISDGRSKINERSLALLSSLGCYQDGFAKDEINEKKVAMHVYEHTTMINITNISESEVSLECNQGTVPIQLLFCLKEQNQKKINSHRWAFEGFAELLRPNIVTLLDAGTMPGKDSIYQLWREFRNPNVGGACGEIRTDLGKRFVKLLNPLVASQNFEYKMSNILDKTTESNFGFITVLPGAFSAYRFEAVRGQPLQKYFYGEIMENEGFHFFSSNMYLAEDRILCFEVVTKKNCNWILKYCRSSYASTDVPERVPEFILQRRRWLNGSFFASVYSFCHFYRVWSSGHNIGRKLLLTVEFFYLFFNTLISWFSLSSFFLVFRILTVSIALAYHSAFNVLSVIFLWLYGICTLSTFILSLGNKPKSTEKFYVLTCVIFAVMMIYMIFCSIFMSVKSFQNILKNDTISFEGLITTEAFRDIVISLGSTYCLYLISSIIYLQPWHMLTSFIQYILLSPSYINVLNIYAFCNVHDLSWGTKGAMANPLGKINTTEDGTFKMEVLVSSSEIQANYDKYLKVLNDFDPKSESRPTEPSYDEKKTGYYANVRSLVIIFWVITNFIIVAVVLETGGIADYIAMKSISTDDTLETAKKAEIPLMTSKASIYFNVILWLVALSALIRFIGCSIYMIVRFFKKVTFR
The following text describes a protein:
Function:
May play a role in ribosome biogenesis.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MGKAAKSSRKGKKAWRSNISTDDIDEFYEKQTRDAHAGAAAIPSLPSDSLFFVDKPASASSSTSSAANANASDPAPKDVPVKRKIEKNREKVLHHESVLKRNPYIQTIPSSLMSKKDKKKFKKHAKKKELQESREEKVVPMEEDSAEKNLDIWGGDAKGAPLPKKGMKRLKKNKSTTSVIPAVEVEPQGCSFNPPHEAHQDALALAVAVEMRKIYTKELGPTPVPLTVLGQAVAEEDKFFLDAADDGDAAADGDVDAAEGDGDQDADALTGERKTKTKRVTRVELNKRARRKERLRTEADAKKLEVLSKQIDSLPNILEEIAKEDKEKEEKRIRLTVAKQERLESAPRRLGRHKFEPAPVQVLLTEEISGSLRKLKGCCNLARDRYKSIEKRGMLAPNKKLSKRPRR
The following text describes a protein:
Function:
Interacts with a short DNA sequence about one-quarter of the way into the major capsid protein gene 23 of T4; general translation inhibition occurs when this late gene of the virus is expressed.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRSPICHLFSAINSSPFKIAPEKEQDLKTIVDDKKIIISVVSEPGFNIRVRKNESNNSHEIVLTVASLEYIWAFSNFFWVFTQEYSKSQKNNDEHFDLTGKNRLKKSDELLKWARKNLQTTGCESWPKKCPKPEAYLQGSEDSQVASEIFLCAIAWILHHEISHVVLQHPLVTTAFSTQEEREADSHATKWILGNLYESAPELKKRALGIATAVLCIQSLEVENYFCLQNTHPAAYERIYSNISCYPVGNEELIEALCTVMLQYLFHGKNINVNLDGESFSSILGDLLCDISRLTSN
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MTPMTTLIMLFSLLLGTTLTLTSSHWLLMWMGLEVSTLAIIPLLTYTNHPRSIESAIKYFLTQATASMLLMFAASLNTWMTGHWTLMQIDNTISSGIMTFALAMKLGLAPFHYWVPEVLQGSSLMSGMILLTWQKLAPISIIYQISPTLNMDILLTLAISSTLLGGWNGLNQTQLRKVMAYSSIAHMGWMVLIIIYFPTLTTLNLTLYIMSTVALFTVFHTTNITKTKPLSLMWNKAPIMTLAIILLLLSLGGLPPLTGFAPKWLVIQELIKHDNMIMATVLAITALLNLFFYMRIIYSSTLTTFPTTNNNKFHWYSKSTKNPLSLPTLVILSTTLLPLTPMFITLS
The following text describes a protein:
Function:
Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Early endosome. Note=Recruited to the cell membrane in response to low extracellular magnesium.
Sequence:
MGEWVIGAFINIFGSVAINFGTNLLKLGHNERERLALQDGGGKMPLKPIIHNQTWRVGILVFLLGNCLNFISFGYAAQSLLAALGSIQFVSNIAFAYVVLNKMVTVKVLVATAFIVLGNVFLVAFGNHQSPVFTPEQLAEKYSNVTFLVYCGILILIVAVHHFLYRKGEVLISTPGQEISSYWKMLLPFSYAVVSGAIGSCSVLFAKSLSNLLRLAMSSSYQLHSWFTYSMLLLFLSTAGFWMTRLNEGLSLYDAILIVPMFQIAWTFFSICTGCIYFQEFQVFDALRTTMFILGMMCVFIGISLLAPDDTRGNETKDNSSSLDSIVSSSVPTEEDRLIPQSSEDGHSKDTRVVVQGMYMKAADLIAKTKTACLAALGFGEDSINASAILVMPMVSSKITGFRGNGLERAKILSMRGSGWSKLAMEEEGTRMLEKTISSKA
The following text describes a protein:
Function:
Transcription factor that regulates gene expression during development. Required for optimal cell growth.
Subcellular Localization:
Nucleus. Note=Predominantly nuclear in growing cells and throughout development.
Sequence:
MEVTNNGSNNSSTIASTNPPTSPSTTSTSKSLPPLSFLNSQWENKQSNNNNNSNNNNINNNNNNNNNNNNNNNNNNNNNNNSVKMEKLIELPSSSNNSPEFLNGVNNNNNGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSGSGGNNSNNNSNISSPPSSSSTSTSVLSSSQSAYMNDKMVAATLDSIGKMESIQRKYEMQIESLMDQIQGYIEKEQKLRSQCQAVEDINAKLENENLQLKKELFEMSRKFKEIDIINLNNTNNNINNNNNNNNNNNNNNNNNSINNNNNNGFSPPPLVKYPSNGSLQQDAKRFKIMEQQSQQQQQMQQQQQIQQQKQYQQQQQQTTSKRKNNISIDGDKEALVAEALGSFVDYAKPSLKRSNSEEVFNSSVYKNKNNINNINNNSNSNNNNGNNSLLNDIQNWQQQQQQQQQLLHQRKKRKDYDYDYNSTQNGKGIPSNSSNNNSSNNNSNNNNNNNSNNNNNIIGSISPPHSSQLQQVSSPQQQQQQQKPNGLKLSISSGSIKDLINSPNKEQSSKSQYPSSLSQSSSIPDMDTDVDSTDEFDFGSNSNNNNNNNNNNNNNNNSNNSNNKKRNNSNNNNLGGDDDDSPDSNDRNGSSSPIDMEPSYDGANLFKTVTPGTITTPQEELLNEIHSLQMQQRETIEKMYIAQKQFLSDRSNGFNNNNEEILRSLQSDQTKLGSTLESELQALNQLYSQTILEPNQLCKLDILLQDVSIQLKQLHLYQMELNYGYGSNEPFPATLVIIKQPFPMVISKFKQLQEDHLCVQLLTGANVEIVSYSPIRAELVFHSKNLTKGSSNLGTQNSLKKNIEKDTQVLDPIKGVAKFPIKFLTGTRKSCVKLHFVLQIKTSDGHIINVPSSTSQPFIVITNDCQWEGSEGTLLKKETFNEKFEISWPHFVNILQKHFLKATKQSPIQPTRPLSMYDFTYLSNTFFGGKPFVSHKDFDSFWSWFGKSIQTLRYKRHISTLWQNGFIFMFLKRDVVTQILKNQDVGTFVILFSEAFPGQLEISYVGTDQKDSLSKSSNDLQSPTTTTTTTTSTRVKHYLVQANDTSGSKRTLPDFLSECNQFTHILQLNIAMIPQTETIPVFKREPKNVVLEPYYSKRQNSQNILGSGYDPLF