lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. Requires trm732 for methylation of the cytidine at position 32 of the anticodon loop of substrate tRNAs. Requires trm734 for methylation of the nucleotide at position 34 of the anticodon loop of substrate tRNAs. Methylates tRNA(Phe).
Subcellular Localization:
Cytoplasm.
Sequence:
MGRSSKDKRDAYYRLAKEQGWRARSAFKLLQLNEQFNLFEGAKRVVDLCAAPGSWSQVLSRELLKNIDTSIAADEKPMIVAVDLQPMAPIDGVCTLQLDITHPNTLSIILSHFGNEPADLVVSDGAPDVTGLHDLDEYIQAQILLAAFNLAVCVLKPGGKFVAKIFRGRDVSLLYSQLRLMFRKVSCAKPRSSRASSIESFVVCEDFNPPSNFQPDLTKPLCVIDPTNAHEIAPFIACGDLDGYDADATYPVEINMKKATLDVIQPPTAPPYKRAIELKHSKMMS
The following text describes a protein:
Function:
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Sequence:
MALGSENHSVFNDDEESSSAFNGPSVIRRNARERNRVKQVNNGFSQLRQHIPAAVIADLSNGRRGIGPGANKKLSKVSTLKMAVEYIRRLQKVLHENDQQKQKQLHLQQQHLHFQQQQQHQHLYAWHQELQLQSPTGSTSSCNSISSYCKPATSTIPGATPPNNFHTKLEASFEDYRNNSCSSGTEDEDILDYISLWQDDL
The following text describes a protein:
Function:
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Sequence:
MSSFDSVAAVAGDGDADDDDVLPPAPFDPAADGAQGGLGALRRGHRFATSYSSFGTAASEDDLAGAGAGTDGGVGAGIPLGSSSNGGAAYGYGGSGDVMNGHVDQIGDVMGGGVVVGDGGGIDDDLFAGAGDGDDGPVLPPPEAMKEEGILRREWRRQNALMLEEKERKERERRGEIIAEADEFKRSFAEKRKLNGDTNRAQNRDREKLFLAKQEKFHGEAEKQYWKAIAEMVPHEIPGLEKRGKRREKQSAEANAKAKQPGVVVVQGTKPGKPTDLSRMRQVLMKLKQTPPPHMAPPPPQPAKDTGGDTDANKDGEAEKAAGEIEKKAAGGEKEAAAGPPVTAAAAADAQANKAAAEETAKK
The following text describes a protein:
Function:
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus.
Sequence:
MSRAVAAGKMPPKRIAKRRSPPEDAIPKSKKVKVSHRSHNTEPGLVLTLGQGDVGQLGLGESVLERKKPALVPLLQDVVQAEAGGMHTVCLSQSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTEDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDTQVVKVASGNDHLVMLTTDGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPRCVLLKSRGTRGRVRFQDAFCGAYFTFAISREGHVYGFGLSNYHQLGTPGTGSCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPVVSSVACGASVGYAVSKDGRVFAWGMGTNYQLGTGQEDDAWSPVEMTGKQLENREVLTVSSGGQHTVLLVKDKTQS
The following text describes a protein:
Function:
Inhibitory receptor postulated to negatively regulate immune and non-immune functions. Upon phosphorylation, recruits SH2 domain-containing PTPN6 and PTPN11 phosphatases to its ITIM motif and antagonizes activation signals. Although it inhibits KLRK1/NKG2D-mediated signaling, it does not bind known ligands of KLRK1/NKG2D and therefore is not its inhibitory counterpart. May limit activation of myeloid cell subsets in response to infection or tissue inflammation. May protect target cells against natural killer cell-mediated lysis. May negatively regulate cell cycle and differentiation of melanocytes via inactivation of STAT3.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Domain:
Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
Sequence:
MSEEVTYATLTFQDSAGARNNRDGNNLRKRGHPAPSPIWRHAALGLVTLCLMLLIGLVTLGMMFLQISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSVLKRQEQMAIKLCQELIIHTSDHRCNPCPKMWQWYQNSCYYFTTNEEKTWANSRKDCIDKNSTLVKIDSLEEKDFLMSQPLLMFSFFWLGLSWDSSGRSWFWEDGSVPSPSLFSTKELDQINGSKGCAYFQKGNIYISRCSAEIFWICEKTAAPVKTEDLD
The following text describes a protein:
Function:
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis; Upon expression in E.coli functions weakly as a triacylglycerol synthase, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Has no wax synthase activity to produce wax esters.
Sequence:
MAQLTALDAGFLKSRDPERHPGLAIGAVAVVNGAAPSYDQLKTVLTERIKSIPRCTQVLATEWIDYPGFDLTQHVRRVALPRPGDEAELFRAIALALERPLDPDRPLWECWIIEGLNGNRWAILIKIHHCMAGAMSAAHLLARLCDDADGSAFANNVDIKQIPPYGDARSWAETLWRMSVSIAGAVCTAAARAVSWPAVTSPAGPVTTRRRYQAVRVPRDAVDAVCHKFGVTANDVALAAITEGFRTVLLHRGQQPRADSLRTLEKTDGSSAMLPYLPVEYDDPVRRLRTVHNRSQQSGRRQPDSLSDYTPLMLCAKMIHALARLPQQGIVTLATSAPRPRHQLRLMGQKMDQVLPIPPTALQLSTGIAVLSYGDELVFGITADYDAASEMQQLVNGIELGVARLVALSDDSVLLFTKDRRKRSSRALPSAARRGRPSVPTARARH
The following text describes a protein:
Function:
Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Activity is the highest with fatty acid substrates of > 10 carbon atoms. Is involved in the aerobic beta-oxidative degradation of fatty acids, which allows aerobic growth of E.coli on fatty acids as a sole carbon and energy source.
Miscellaneous:
MISCELLANEOUS: The enzymatic mechanism is a two-step reaction that proceeds via the intermediate formation of an acyl-adenylate (acyl-AMP) intermediate.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Note=Partially membrane-associated.
Sequence:
MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVNMGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVVNVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAKGTVVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTTGVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELGGQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGGMPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLVDDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRIVDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSLTEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MAWTGTLSRSVKEIRFLFCQSSPASFAAREFVKKNYAEIKSRNPSVPFLVRECSGVQPQLWARYEMGVERCVNLDGLTEAQIDRKLQELAKIGESAKAK
The following text describes a protein:
Function:
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Sequence:
MADLLKEGTKHLSGLEEAVLKNVEAVRSLSQITKTTFGPQGMKKLIVNNRGKQYVTSDAAKIITELEFKHPAANMVINAAKQQQAEIGDFTNLVIMFAGELMTQAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSKGEEEMLKELVNKLKEQGVKAVICGGNVQDLALHYCDRAGIIVIRVGSTFDLKRLCRVTGATPFISLTTECDSGNFGMCEKIYVQEIGSTKCTVFERKESAAVTTIVVRGSTQNILDDIEQAIDDCVCEFKILERHKKFVGGAGAFEIEMSKKISEVGDKCDGLKQYSIKKYAEAFQMVPRVLAENAGLDATEILSELFVAHQNDISMGVNVDSNTQLLNTKQEMVFDNLEAKKNAIKLATNIATTILLVDQIVMQKPAGGPKIPQQRMQGPMDQNDAGF
The following text describes a protein:
Function:
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
Sequence:
MGLNLKDLVVREKTTLEAFSNKVIAIDAYNAIYQFLASIRGPDGLQLSDSEGRITSHLSGLLYRNVNFLSLGIKPVYVFDGKPPSLKTAEIERRKQIKMDATIKYEKAIADGNMEDARKYAQQTTSMKDGMVKESKQLLTYFGIPYIEAPSEGEATAAHLTNTGQAYASASQDFDSILCGAKRLVRNFTNSGRRKIPNKNTYIDIVPEIIETQKTLDSLELTREELIDVGILIGTDFNPNGFERVGPKTALKMIKQHSKLEEIPQIQEQLEEIDYQEIRKIFLNPEVADVKEIVFENVNYEGMSNYLVRERSFSEDRVNSTLNRLKKALEKKSQNLDQWF
The following text describes a protein:
Function:
Polymerase that creates the 3'-poly(A) tail of mRNA's.
Subcellular Localization:
Nucleus.
Sequence:
MATAAPKQLGITPPLSTALPTDAEKQATDALIEELTRENNFESRADTDKRTAVLASLQNITEEFVKRVCRKQNLPENYINNAGGRIFTYGSFRLGVYGPGSDIDTLVVVPKNVSREEYFEMFPDLLVEMAPKGAIEDLTPVQEAYVPIIKFEYSGISIDLIFARIDTLTQVPRTLTLKDDNLLTGLDDAGLRSVNGTRVTDDIMDLVPEKAVFRNALRGVKLWAQRRAIYANIMGFPGGVAWAMLVARVCQLYPQATASTIILKFFRIMEKWQWPQPVLLQQIKNGKLNVRVWNPRVYKSDSFHLMPIITPSYPSMCATHNVTKSTKEIICRELARGGNIVDRIMMGKAPWKDLFQKHTFFTKNYKYYLSVISASTTKEAQLIWAGLVESKVRLLVTNLETHESIALAHPFNKGFERVHKCSSEDEIESVKEGGHQYQIYEIPTVTTDPSHDPSLGIAVKDQNGDVPEPEPEKKETMVYTTTFYIGLELREGAKSLDLAWCVDDFKDRCRSWEKYNEELNTLSVIHTRNCDLPDDVFTEGEVKPTRSQKKKKRPASDDAKQAPAKRQQVVAAG
The following text describes a protein:
Function:
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWEFKVSKIPGTFKQLTLNLGGRVPFILCLISFFLLLFSLVRHTKQIQLHATGFRDPSTEAHMRAIKAVIIFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFVKGFLRRRKPFVP
The following text describes a protein:
Function:
Component of the cell wall. Major cell wall protein in stationary phase cells. Required to stabilize the cell wall in the absence of multiple GPI-anchored mannoproteins.
Miscellaneous:
MISCELLANEOUS: Present with 1630 molecules/cell in log phase SD medium.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Domain:
The number of the intragenic tandem repeats varies between different S.cerevisiae strains.
Sequence:
MKLSTVLLSAGLASTTLAQFSNSTSASSTDVTSSSSISTSSGSVTITSSEAPESDNGTSTAAPTETSTEAPTTAIPTNGTSTEAPTTAIPTNGTSTEAPTDTTTEAPTTALPTNGTSTEAPTDTTTEAPTTGLPTNGTTSAFPPTTSLPPSNTTTTPPYNPSTDYTTDYTVVTEYTTYCPEPTTFTTNGKTYTVTEPTTLTITDCPCTIEKPTTTSTTEYTVVTEYTTYCPEPTTFTTNGKTYTVTEPTTLTITDCPCTIEKSEAPESSVPVTESKGTTTKETGVTTKQTTANPSLTVSTVVPVSSSASSHSVVINSNGANVVVPGALGLAGVAMLFL
The following text describes a protein:
Function:
A murein DD-endopeptidase with specificity for D-Ala-meso-diaminopimelic acid (mDAP) cross-links. Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion. Functionally redundant with MepM and MepH. Partially suppresses an mepS disruption mutant.
Sequence:
MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKADKKKSTATTKKTQKTAKKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNKTASASFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPYRWGGSSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRTQGRGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR
The following text describes a protein:
Function:
Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.
Sequence:
MPPLKLNSKNLAAILNAGKGQIKVPTYPRNGAVKEGIVHIGVGGFHRAHLAVYIDRLMQNHGVTDYAIAGVGLTPFDKKMRDILRSQDHLYTVIERSAKGSFANVVGSINSFLFAPDDREAVVAKMAHPDTHIVSLTITESGYYYNENTHELVSEHPDIQFDLDPANEKTPRTTFGFLYAALARRFKQGLNPFTVMSCDNMQKNGAITRHMLESFARLRNPEIAEWISKKGHFPNAMVDRITPQTAPADITALANDFGIQDDWPVVTEPFMDWVIEDHFCDGRPPFEKVGVKVVKDLRAVEEYEKHKLRLLNGSHSAIGYAGQLAGFQYVHEVLQNDTYKKFLWQMMQEEVKPLLPEIPGVDIDEYCRTLIERFSNPTIKDQLPRICLNASGKIPQFIMPSIAEAIWVTGPFRRLCFVAAAWFRYLHGVDDAGNKFDIEDPMLEELQAKAKAGGLEPHEILSIKSLFGDDLRGDKRFLQEITTAMQLIDRDGVLKTMPKYVD
The following text describes a protein:
Function:
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
Subcellular Localization:
Cytoplasm.
Sequence:
MPMWNIHSLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDAISAFEIEREAFISVSGTCPLYLDEIRHFLALCPELSLGWFEEGCLVAFVIGSLWDKERLTQESLTLHRPGGHTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCEEALVPFYEKFGFQAVGPCAITVGSLTFTELQCSLRCHAFLRRNSGC
The following text describes a protein:
Function:
Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endomembrane system; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MDITSLFKASVKTVRLKLPPQSVAPLDKNRILQKKKPTPEVWGKAKTLKQQVTLLRNFLIENRAAYMQLAEHLKNSAPQMTNEERDLIDRETESTLADAGTLIAGLRHECAELKADRQVKEFLGLVVDSLFEYANGIRRIAQEQKQFRQRRQMETMHYIKLQPKMKTDPYTKPLEAVPSEREAVAAAAVVAPARTGDSLDSSRSADKTMTQTVEDMQDSSMYEEYESNDLSPEDIQMFESENIQLYNELKGLSEEVEQIQRNVADITQLQDIFTEKITLQNTDIDRIATNVIGTTENMNDANEQIKQAIQRNAGLRVWVLFFFIVMSFTLLFLDWYND
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
RDFIEQHYVELKKANPEFPILIRECSGVQPKLWARYDFGKETNVSLNNLNVDQVARALESVVTRKP
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MEEWDVPQMKKEVESLKYQLAFKREMSSKTIPELLKWIEDGIPNDPFLNPDLMKNNPWVEKGKCTIL
The following text describes a protein:
Function:
Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis.
Subcellular Localization:
Cell membrane.
Sequence:
MTGETDRFDDPQAAETPRRARTPSEPLITAKLYGEEPHLCADSPESRWTMEDLTFSEELYQAKGTTDEPKHYQKNTTHRNTNHHLHHHHHHHNNSNQLHPNRNYNNQYSDPFDYKNTSHSEFKKFMNNNNDDMDLNYLRPPSPLRHHRTRSTSLPFLTLADLPALQKQRPLRVVVLGDSGVGKSSLAVQFVASLGEYNDYESVLSENPDEVYEKTMQIDGQEITVQIVDTPPYGQAEFEEREDELLQGGDAYILVYSITNRRSFKKANELRFKLQRTQATEMVPIILVGNKTDLERSREVPFEEGKHFAALFDCKLIETSASLSHNVDKLFNGVVQQIRLRRDRRHSEEEMETGSGGSVESLKGSPTRGERQRSPSKKSRRPSMLKRARGAIGRLLRRKSGDEPTPGYRARSKSCHVMEVL
The following text describes a protein:
Function:
DNA-dependent ATPase and 3'-5' DNA helicase. Required in the control of double strand break transition and crossover during meiosis. ATPase is slightly better stimulated by single-stranded (ss) than double-stranded (ds)DNA. Unwinds Holliday junction (HJ) DNA to Y-DNA and to ssDNA. Efficient unwinding requires 6 nucleotides of 3'-ssDNA; seems to initiate unwinding from blunt ends when they open slightly. Binds HJ, dsDNA, ssDNA and 3'- and 5-overhang DNA.
Subcellular Localization:
Nucleus.
Sequence:
MKTKFDRLGTGKRSRPSPNNIDFNDQSATFKRNKKNSRQPSFKVGLSYNSLLDDCDDENETEEIFEGRGLQFFDKDDNFSITADDTQVTSKLFDHDLEQTPDEEAKKPKKVTIRKSAKKCLSTTILPDSFRGVFKFTEFNKMQSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCYEMYKNWFPSFVNLSVGMLTSDTSFLETEKAKKCNIIITTPEKWDLLTRRWSDYSRLFELVKLVLVDEIHTIKEKRGASLEVILTRMNTMCQNIRFVALSATVPNIEDLALWLKTNNELPANILSFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFCPTRASTISTAKFLLNNHIFSKSKKRCNHNPSDKILNECMQQGIAFHHAGISLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNSSEIQEYSDLDVLQMIGRAGRPQFETHGCAVIMTDSKMKQTYENLIHGTDVLESSLHLNLIEHLAAETSLETVYSIETAVNWLRNTFFYVRFGKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDTLVKVKIIDISNGEYKSTAYGNAMTRHYISFESMKQFINAKKFLSLQGILNLLATSEEFSVMRVRHNEKKLFKEINLSPLLKYPFLTEKKQSQIIDRVSQKVSLLIQYELGGLEFPSYEGASKLHQTLVQDKFLVFRHCFRLLKCMVDTFIEKSDGTSLKNTLFLLRSLNGHCWENTPMVLRQLKTIGLVSVRRLIRHGITNLEEMGHLSDTQIEYYLNLKIGNGIKIKNDISLLPCLNIRTKLENCKIENEELWLTFKVEISATFKSSIWHGQHLSLDIETEKSSGELIDFRRLQVNKLQSPRGFRISAKISPKLEKIEFSIHCQEIAGLGKTIVYSTDHLASQFSAKTPNIRKDLNSLEKCLFYESSSDGEVGKTSRVSHKDGLEESLSSDDSILDYLNERKKSSKAVESAAVIHPEAHSSSHFSNGRQVRSNGNYECFHSCKDKTQCRHLCCKEGIPVKYIKEKGPSSIKPVSKPDQIRQPLLAKNINTTPHLEKRLNSKPKQWQEENTDIATVHTLPSKIYNLSQQMSSMEAGEQVLKSGPENCPEIIPIDLESSDSYSSNTAASSISDPNGDLDFLGSDIEFE
The following text describes a protein:
Function:
Iol operon repressor.
Sequence:
MKLMRIQEMEEYILSHGTVSLDELCQVFNVSKNTVRRDINKLTEKGAIEKVYGGVTSIEKTALVPFENRTIQHQDEKTKIAHYASRFIEDHDLVFIDSGTTTKSILDTLDPAKNVTILTNSLDIINAASALKNINLIIIGNNYKRKTRSFVGMDDPAMLDKYNINKAFMSATGTTLTHGLTNSDLLEYEIKKRISEKAKEVYLLADHSKFGKSTLLTYAPFDRLHCIVTSQPLDDEYTQYCNEHQIGIHLA
The following text describes a protein:
Function:
Acetylates soluble but not nucleosomal H4 (By similarity). Acetylates 'Lys-12' of histone H4.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MVQKQQASAGPGTEPKKRRRVGFSPADTGVEANECIKIYLVSSKEEVDSSDISSVKPVDLNDFFDGDGKIYGYQGLKINVWINSISLHSYADITYQSTINGDKGITDLKSALQNIFAETIVDTKDEFLQTFSTQRDFIRNMVSNGEVMHAGATDGSSKNAEVVPSDPQVIRMEIGSPNAGLLYSRLVPLVLLFVDGSNPIDVTDPDWHLYLLIQKKEEKEDPLYRIVGFTAIYKFYRYPDRLRMRLSQILVLPSFQGKGLGSYLMEVVNNVAITENVYDLTVEEPSEKFQHIRTCIDINRLRSFDPIKPDIDSAVQTLTKGKLSKKAQIPRFTPPLNAIEKVRESLKINKKQFLKCWEILIYLALDPIDKYMEDYTSVITNHVRTDILGKDIETPKKQVVDVPSSFEPEASFVVFKSVNGEEANTNVQVDENKPDQEQQLKQLVEERIREIKLVAEKVSKSGQTLKV
The following text describes a protein:
Function:
Major early eggshell protein.
Subcellular Localization:
Secreted.
Sequence:
MKTVAFLAVVVLFAAFACASCSSSYAAPAPAAAPASSYSSVPAPPCPKNYLFSCQPNLVPAPCAQQAAPAAYGSAGAYTEQVPSYIGFAPYQQLQQYHQRIGNAALIDELRSLGQGIQGQQY
The following text describes a protein:
Function:
Heme-containing signal transducer responsible for aerotaxis, the migratory response toward or away from oxygen.
Sequence:
MSNDNDTLVTADVRNGIDGHALADRIGLDEAEIAWRLSFTGIDDDTMAALAAEQPLFEATADALVTDFYDHLESYERTQDLFANSTKTVEQLKETQAEYLLGLGRGEYDTEYAAQRARIGKIHDVLGLGPDVYLGAYTRYYTGLLDALADDVVADRGEEAAAAVDELVARFLPMLKLLTFDQQIAMDTYIDSYAQRLHDEIDSRQELANAVASDVEAPLSSLEATSQDVAERTDTMRAATDDQVDRMADVSREISSVSASVEEVASTADDVRRTSEDAEALAQQGEAAADDALATMTDIDEATDGVTAGVEQLRERAADVESVTGVIDDIAEQTNMLALNASIEAARAGEAGEGFAVVADEVKALAEESREQSTRVEELVEQMQAETEETVDQLDEVNQRIGEGVERVEEAMETLQEITDAVEDAASGMQEVSTATDEQAVSTEEVAEMVDDVDDRAGEIAAALDDIADATDQQVRTVEEVRETVGKLS
The following text describes a protein:
Function:
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELRQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSADLVQPASGGSFNGFTQPQDTSLFAMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATLPAGEGVSLEEAKIGTETEGAESAQAEAEELAATVPQEKVIPSVVIEPASNHEEEGEHEITIGAEPEETTEDTAPLGPTSETPELATEPKPLQDPQPMPSAPALGTADQLASVREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
The following text describes a protein:
Function:
Catalyzes the reduction of NADP in the presence of molecular H(2) to yield NADPH.
Sequence:
MQNSTCQAVGECRVPEHAVLPQPLYREVVQFIESLPQKEGHLVTVLHKAQSVFGYLPIEVQQFVADHMEVPLAQVYGVVSFYTFFTMVPKGKYPISVCMGTACFVKGADKVVHAFKEQLKIDIGDVTPDGRFSIDTLRCVGGCALAPIVMVGEKVYGNVTPGQVKKILAEY
The following text describes a protein:
Function:
Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
Subcellular Localization:
Cell inner membrane. Cell membrane; Multi-pass membrane protein.
Sequence:
MEGNYAKDVLAIGLTLIMAMMLTILPLPAWAVWYQPAWIFMVLLFWMIALPYRVGIGAAFIWGLLFDLLSGTILGQHALIFTIIAYFIIRFQTPLRSLPNWQQMILVFIATAVYLALQYWIMAMADASPETAKYWLPLMSTTLLWPWVRVLLKDYQSRFRLG
The following text describes a protein:
Function:
Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.
Subcellular Localization:
Cell membrane. Membrane raft. Membrane; Single-pass type I membrane protein.
Sequence:
PVCKDNICLSNCNLSSYCSFTEEICIAIWRKTNETMTVHTMCHHPNLPLEGINPRLLLNFTSRECHMLPQPADEGVMMVCGCQGEQECNDKLIFDKGVIKMDREHISFPTSGFSRLHSKDVIPVVIVSLVPPLLVAMVATAVFYSYRMRRPDKPGPASRSDWPTKRSPELYQVLDHPRGEAGGGVVVLGVEPVINNTKGRCPNKITVGKRIAELLPIKLEDVVGRGRFAEVWRARLLQSDMGGVNSYETVAVKVFPNVEYASWRNECSILSDPTLQHENLVQFLAAEERSLPSDTLRTYWIVLAHYSLGNMQDHLTANTLSWEELVSLASSIANGLAHLHSETKLNGAPKVPVAHRDLKSSNILIKNRKQCVLCDFGLALRLDISLTVDDYANSGQVGTARYMAPEVLESRVNLEDLEAFKQMDIYSMALVLWEMASRCDVIEEVKAYQPAFGSKVCEQPCVDSMRDLVLRDRGRPDIPSAWTQHQGMSVFCSTITECWDHDPEARLTAHCVVERFNAMQHSEEEAVLEDGGLGGGRQEHKLNQVIPTISPEQAEAEEIKASIETSVTLDCFTAVDQAEITSVIKAS
The following text describes a protein:
Function:
Possible role in the function of olfactory neurons.
Subcellular Localization:
Nucleus.
Sequence:
MNTADVPDNLQSWGQQPSSSYSNTQQHSQMTNLPPINHNNLCDTEPMNEDFQLQDVQADELQKQQKQQEQQHIQQQNAQRFIAQSRQPHSNILRFPQPPITSIKTNSHAFYPQQEVTQVRPKKHRVSMTNAEAALTPGMPPEKQAAKKRNIGQFSTDTVPAGIGMIGIPFESTSKPLQIQQFRNPQDAPVRKLTSDLIKTYKAINESFYLRKQVRRDRHKSQDAGKPKGSKDGSGASLTDTFSIHNAIPITSSDNHYQQDAHQNAPPLLDTNAPPTSTMVVPMRTETDLQQQQRQKSSRGGPYNNGYDDQNYDYILKNGEIFDKRYVILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNTSFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMHTGEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSVEDYSKFKDLIKRMLQFDPKQRISPYYVVRHPFLKQKEERVPSQPPVSHSNLQQQQQLYIQQPSSQMSQVMESPSVGSVYVEDNGMYRQAPGSSANPISVTSSFDEGDAMEVDAGRRRFSAHQQNYHNPNYQYSQPQQQQQQQYQQTQRTQLEQQQKQAQLQQQLQQQQMQQQQQQQQQRQHMPQAQSSSQQHLQSRARPRQQDQNEWRNQFELDDTFQQKQRKVDDSVSNQISRNQFNPQQVSMTHGNVNANNREMEKLDYPNNKL