lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Tor2 is essential for growth. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ribosomal protein gene expression. TORC1 negatively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Represses mating, meiosis and sporulation efficiency by interfering with the functions of the transcription factor ste11 and the meiosis-promoting RNA-binding protein mei2.
Subcellular Localization:
Cytoplasm. Note=Localizes at the barrier septum.
Sequence:
MERPSLSRRTSSSTVSTDGEGVYSRSTKERKRNFIVNSRLKRGGGHVRVNRSGRLGSVTMRPSALTRAHSQNPNSSLVNNSSAVSHLTKQRSLNDLHELNGPKHVAKNGLIPLTQRKPNCVWDDAPVDNDSTAGNLDSDSALPTPSVTTNEAADSSRASSPVTRVVAVHDNKKKIINSNISNAPPFNNTDVQASARPPAAGQDDSAADASTTKSSPVHNEVMAEPLPHSNNREVTQATNQPKWQIHSGSDIASEPPTLSRGNSLSLLANRKVPSTNVKKSQAELYDLGSSTSRTQQKLLIQRASSKFDIVEDDMDTNPSKRFSNPHTKHIMDLVRTQYRNVLRTRELIPEFLEKIRSSYSNNQNFDSQNAFNTSAAGTAGTREETISNGQNGIVASAETSKKDDGVQSASLNASMSARSHARQRSIHVPKTRKDTDYESIHQKLLQLWSQG
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Apical cell membrane. Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MNPSLSQCSVTVCINLSLSPRGCTDIICCVLFLAAIVGYMIVGILAWLYGDPRQVLYPRNSTGSFCGVGENKDKPSVLYFNILKCATSTNIMAAALNGLQCPTTQICVATCPNDFWIVPPQGYMQPPKSVFQQQYCVPSFNLATTNMSTSDVINKELCAYFYTPSSSVLGRCLPSMGSLSVIPSNFSIPGLSSANQTASRIRNATQDVVLGFNAKEIGVRIFEDFAVSWYYMCVFTVCVVLVSVCVCFYLCGCCGVLVFLCVFTVCVVYVRVFLSVWGSCVCVCGCLLCVCSVCGCFYLCVGVVGFLCLCVWVFTVCVVCVGVSICVWVLWGSCVCVCGCLLCVCSVCGCCGVLVFVCVCVYCVCVVFVWVFLSCVRVFLSVWVLWGSCVYYVCVVCVGVSICMWVLWGSCVCVCVYCVCSVCGCFYLCGCCGVLVFTVCSGAGVRNDEVSRFHPDWGVCVCVSAPPDADLSLCPSVPRSLRPCRYHVGSLAFGALILTIVQFIRILLEYLDHKFRAAQNPCARFVMCCLKCCFWCLEKFIKFINRNAYIVPEPLGVVSARPGQGVDLCVQRSGPGSGGRCEGLTVLTVVVGSYLVAQGFFSVYSMCVDTLFLCFLEDLERNDGSVQKPYYMSKSLMKILNKKNKLPKAE
The following text describes a protein:
Function:
IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein. Late endosome membrane; Single-pass type II membrane protein. Early endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. Cytoplasm, perinuclear region. Note=Co-localizes with BRI3 isoform 1 at the perinuclear region.
Sequence:
MNHTSQAFVNAATGGQPPNYERIKEEYEVSELGAPHGSASVRTTVINMPREVSVPDHVVWSLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDMTGAQAYASTAKCLNISSLVLSILMVIITIVTVVIIALNAPRLQT
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Sequence:
MPDTTQDPPTHTDSTPQGTPGAIMNPQAPPVISIDTSIVDADEKHPPVLIEPTNSYSPTIKEETATPSTCNDSDFSTHAEEAQQHLNEDADGTLAGGYKWAPKQLSHLIDPKSVFVLAEMGGLEGLATDLNTNLQSGLSEEDAGARDARIEAYDRNILPEKKAKSLFYLMWMALQDKVLILLTVAAIISLALGLYETFGQPAEHDAQGRKLPKVDWVEGVAIMVAIIIVVVVGAGNDWQKELRFVKLNKKKEDRMIRVIRSGKTQEVPIADLLVGDLVLLEPGDMIPADGILVSGHNIKCDESSATGETDTMKKMSGFDAMTAYESRVDGLTRGKVDPFILSGSKVLEGIGTYVVTAVGPNSLFGKTLLSLNIEDEATPLQAKLNDIAEGIAKAGGLAALILFIVLFIRFCARLPGNKDTPAEKGNEFMDILITAITIIVVAVPEGLPLAVTLALAFATTRMLKDNNLVRELRACETMGNATTVCSDKTGTLTENRMTVTRGTIGVEEFAVEEITQFFETLPAEAREILFESIVFNTTAFETDQIADTDAERFVGSKTETALLNFAHLYMGLQNLANQRDAREIVQIVPFDSSRKCMAVILKMKGFYRMYIKGASEVLSAQSSMIYNNNVVSPITKEQRQDIDQKILHYGEQSLRGIALAYRDFECSSWPPKGMASSDDSSQAEFEPMFSDLTLFGLIGIMDPLREGVTKAVADCQSAGVIVRMVTGDNVNTAKAIARECGIYSEGGLVMEGPVFRRLADHEMKEMLPQLQVLARSSPEDKRILVKALKEMGETVAVTGDGTNDGPALKLADVGFSMGIAGTEVAKEASSIILMDDNFSSIVKAIMWGRTVNDAVKKFLQFQLTVNVTAVVLTFVSAVVNKHGKSVLTAVQLLWVNLIMDTLAALALATDPPSPDVLERKPDRKSQNLITVTMWKMIFGQAIFQLGVTFVLFFAGKYFWTVDTPRQQDELDATVFNTFVWMQFFNLFVNRRLDNKMNMFSGIHRNIFFILIVVIIGGFQVLIMFVGGAAFSIVHLNGGQWATSLICGVISLPAGMLLRLIPDAWISAMYPQFLHNWISKLWRIMRPKNKEIVEIHVPRDDGFQGSDYKWHSGIEEARVQLEFMRALRGGRMYQVPNLVPVKIRQMFQRSRANSVASLSKKEPSVSTTTASPTQTVFDESGRDRWTENDGHLAVPGAHYGGSGNGNNGNTSPTSPGGSSSRSSSRGSSIGALVMVPAIVGGAVAGWNPELKPPSN
The following text describes a protein:
Function:
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MKEYIVYLQGLLKQNNIQFEQEEDFAQSKLNQINNEFGYEHINRYKRQMILSEIGLTGQQKIHLAKVLIVGAGGIGAPAIYYLAGAGVGTIGLVDGDSVDVSNLHRQIIHNNDRQGMNKCESAKKQINQFNPLVNVITYQHHLSSENAIDIFKNYDLILDATDNPATRYLINDTAIYLNKPLVSGSSVGWEGQITVYGMQGPCYRCLFPQCPKTVQNCNEAGVFGVMPGLIGLIEALQAVKIIIGQQTLSQKMILIDGIRDVYKVVKLRGQQKDCIACQKQIKINEYDYASFAQTICSTSIPFRGGYKEIEWKDFLQIQKNDNVVLLDVRPSQQYNIIKLDGFKNLPYQQIDQFQVEENKDKEVYIMCRRGNNSRLACEFLKDKIPNVYNIVGGIDLYAKGFDPKMPLL
The following text describes a protein:
Function:
Has a role in meiotic nuclear oscillation and recombination. Required to remodel astral microtubules into the 'horsetail' astral array maintaining the 'horsetail' nuclear movement. Promotes homologous paring of chromosomes during this movement.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Localizes to the spindle pole body until the onset of meiosis I.
Sequence:
MEYQEEASLASAEDSTFIASSPVQSVSEMKSIKQKSFQYFDDYEKNVSDKTIQFQKLQMTAKEIIDAFERDSTQRTLQIESLESKIGEQERDLNNEKLASETLREKTQLLEKENGALKVENGYLYEKSRKLEEEMAHLKKKCNVYKSKFEESSLRCKSLYSSNTKLKDSMETMKRRMETETKEMNKIKPKNDSESDRFKRNSQSLSQQSPLLDVHSPDNSNHRTMLNINNSSPIKPKKIFKPNEVKNRISRLQKTFADLENQHHSFQQICQTLRKRLENDSSTTKQRLSKLEEIIRNRAPPSYSFSLNCSHTYQPVSCVEPVNHDLS
The following text describes a protein:
Function:
Ligand-activated transcription factor (By similarity). Involved in lifespan extension in a manner dependent upon mitochondrial function.
Subcellular Localization:
Nucleus.
Sequence:
MERGSPGSSKSVSTFTPDSMSTYVSNCVVCGRLTSLFNYGAHSCSACGSFLRRTLASSKFLDDCKYSGNCFENFKRAIHFECKFCRLHKCVQKGMLDLSRYTHLERLICELSEFDSKRETLFLTMTVSNGFKAEELMWQSSVSLVKKPPHLVFNSHDWGFMNQVTIIDFLKKLEFSKFLSSQDLRSFLKCTHFTQVILKSAVISYNANQNYMSFPNKIDIFPETVTEGTSISVNLQNRIRCRLVNRLIELKVTHEEMLLLCAIAFSNPAIPELSENGRTLLNSYQNVYRSALFQYCSTAYQRNGPSRFNDLLFLLHVVTKTHDDIKKYFTLFQFFQPTEQPSQVHQDVIEFIN
The following text describes a protein:
Function:
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
Subcellular Localization:
Cytoplasm.
Sequence:
MKGVYFVSGIDTDIGKTVATGVLAKQLLQQGKSVITQKPVQTGCQNIADDIAVHRKIMGIPMQEADKRRLTMPEIFSYPASPHLAARLDGRALDLDKIRTATQELAAQYEVVLVEGAGGLMVPLTENLLTIDYIRQQGYPVILVTSGRLGSINHTLLSFAALKQYGIRLHSLVFNHIHDSRDAHIAQDSLSYLKCRLKADFSEAEWMELAKTDAV
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MELTAEKPAVSKTASMEQKSPLYKPLWQLTEDDIVQVTREDCRRFLKEKGMRRPSWNKSQAIQQVISLKALLEPNDFGHSSVSSPPDHQKTFRFSSSSPRSPDLLLPTSEQKKELSVGGGSRSQQRRDPPVEIAGVSARKTGEALAGQMTVFYGDEVSVFDGVLVDKALAILRIAASQDYHNRQFSNMVVDLNKPFNPPLPYSVQATVPPPTPVNNVKFPGCLRDGSERKIPREFEPEGPTYRKASLQRYLEKRKDRKTFKCKRNTNCLPPPPLLPSSMDLYFTQKFRRENSNGKQCQSVSTVCPHPTHPQIPTHCTSVVNRTQNVGFSFDLNNADV
The following text describes a protein:
Function:
Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
Subcellular Localization:
Cytoplasm.
Sequence:
MKLSALYQIFLDCQLVTTDSRNCPEGSLFIALKGESFNGNAFAGKALETGCAYAVIDESEYAIEGDQRYILVDDCLQTLQQLANYHRRQLGTRVIGITGTNGKTTTKELISAVLSQSHNILYTLGNLNNHIGVPSTLLRLKAEHDLAVIEMGANHPGEIKFLSEIAEPDCGIITNVGKAHLEGFGSFEGVIKTKGELYDFLRKKEGSTVFIHHDNAYLMNIAEGLNLIPYGTEDDLYVNGRITGNSPYLTFEWKAGKDGKSYQVQTQLIGEYNFPNALAAITIGRFFGVEDAKINEALAGYTPQNNRSQLKKTDDNTLIIDAYNANPTSMMAALQNFRNMEVPHKMLILGDMRELGAESAAEHQKIADYLKECAFEKVWLVGDQFAAAEHSFQTYPNVQEVIKELEADKPKGYTILIKGSNGIKLSSVVDYL
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
Subcellular Localization:
Cytoplasm.
Domain:
The pumilio repeats mediate the association with RNA by packing together to form a right-handed superhelix that approximates a half donut. The number as well as the specific sequence of the repeats determine the specificity for target mRNAs (By similarity).
Sequence:
MAVADNPFSMSTMFNALPNPKGISGSIPPPGFAPRASATPLHAALFNLMTDGDGVSYFKEMISNSDKTELQRMASLLTSDSDYFMSIVTTKFGSRRVQKLLGKSDDVDAFFCAAILRRFLHITTDKYASYVTIRAMVVFDKVMKKALYERILYHALDLACDQHGCIALNDIITDADDPYYRDQLLELVASNALRLSNDASGNFVVQHVLTLYDSRCIHNIAVNLYGQCIELSFKKYGSYIVEKLLEVEESMVVVVVELLGCDGDRLMRLARNEFGNFVVVKALRFTKMSRMDLFWGLVQKLMPFIRLLRRSHGSNIANILDSFRLRC
The following text describes a protein:
Function:
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.
Subcellular Localization:
Nucleus speckle. Nucleus, nucleoplasm.
Sequence:
MFPAQEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCFKHPESVSYAIALLNGIRLYGRPINVQYRFGSSHSSEPANQSFESCVKINSYSYRNEEMVVGRSSFPMQCLPIHNTSLPQEYFPFQKMQWHAYNPVLQLPYYEMTAPLPNSASVSSSLNHVPDLEAGPSSYKWTHQQPGDSDLYQMTAPLPSSASVSSSLNHVPDLEAGPTSYKWTHQQPSDSDFYQMNKRKRQKQTSDSDSSTDNNRGNECSQKFRKSKKKKRY
The following text describes a protein:
Function:
Transcriptional activator that induces gene expression by binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Required for proper morphogenesis of the spermatheca and the spermatheca-uterine valve formation. Promotes cell proliferation and differentiation of the spermatheca precursor cells during spermatheca development in larval stage L4. Might play a role in promoting G1/S phase progression in the spermatheca precursor cell lineage. Also required for the differentiation of the spermatheca-uterine junction core (sujc) cells which are generating the spermatheca-uterine valve.
Subcellular Localization:
Nucleus.
Domain:
The NR LBD domain and the nuclear receptor DNA binding domain are sufficient for binding to the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'.
Sequence:
MEQLSIQTDELQDQFSNCSPASVDSSYSSCSSVEDEIEIYTRLVRNEEPLRRDFFREMSKNSSCSSSFDYGEFGPSSSSRKGSKTTDADLDSLFHSLVETSDQVNTVPKPTKTEVESIPEEFEQKPSSSSHRLPSEMNASITHIKSELDPTMQAFQMPHNDLFLATAAPHYNPFALSNDFMPNPLMPSFTSPFYPQHFPVSDSRRGSQGTTSSSNNTGGTPSPHSSSLPTSPPQLQGFLRSFLNPDNLSTPTSFGVPSETALDADKMCAVCNDRAVCLHYGARTCEGCKGFFKRTVQKNSKYTCAGNKTCPIDKRYRSRCQYCRYQKCLEVGMVKEIVRHGSLSGRRGRLSSKTKLARSEDQPSPPLPLLALMGKAIEDHTNMTVVRQFMQPFDETIALRILHGELHATKKLLMAMPQISEIQPADFQILLSRSFFAIMAIRVANRCGNSTDTIMFESGELFSLNAFPACFQQIIRFMVDKARTFSSLVDWEPQAFAAFIALQFLAGNTEHNVLGLTNKPLVDQVQSTIINALKDHCSGSQNKLAKIVRLTQEFDVFHALGLQALDILYPSHQLPEEFMFLINLTRAPLRSTDAPPACGSPVAPSGSSLFNFQMGPAAF
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Subcellular Localization:
Peroxisome matrix.
Sequence:
MATGWRGAGVLVLAGRAAAAAAASPFGNTWALKWRTFATGAAAMAALKVGDKLPSVEVYEGDPGTKVNLASLFKGKKGVLFGVPGAFTPGCSKTHLPGYVEKAGQLKGKGVEIIACLSVNDVFVMKEWGNAHHAEGKVRMLADPTGAFGKATNLLLDKEPLRDLFGTNRSKRFSMVVDDGIVKSLNVEEDGTGLTCSLATNIVSQL
The following text describes a protein:
Function:
Probable transcription factor. Seems to act on the expression of the genes culC, culD, rnpA and sigB.
Subcellular Localization:
Nucleus.
Sequence:
MMGEFHTQFQQIKQNNINNNNNNNNNNSNNNNNFDPITSLTNNNNNKIISPLNSNRQQPNSNTNNNSNNKNNNKSNLLDIILDNNNLENNIDNNNNNNNNNNNNNNNNNNNNSKSIINLIDNNNNNNKNNNNNNNNNNILKIPIDYTPVDKNTESIFKGFSPFSFKQQQPIDTSDQQQKETKKLQLNINSNNKNNNNIINNSNNNNNINNIESNNNNLNSASTSPIPTPTSLTAVSVPSSSPLPSPTSPNTILQSPTTTTTTTTTTSNSSVSPQPTQINKTDKYLLPMSAPRSCEFCGSSQTPTWRRGPSGKGSLCNACGIKWRLKGKDGIFKPSQKQQNRQKPIMSAQKQPKQQQNQPQQQQPQQPQQPQQPQQQNQQQNQQQSIQSQPQQRQNNHLILNQQTINQHLQMLSKQHQQQASQSMFQQQQLHNNQHSNDSNYNSYNNNNNNNNNNYSQHEQLPPISSYNSMNNNNNSNNSNNNNNNNNYSQIPQYGSDDNVSVPNQSPDSYKPSKKRKPEFIHTDTSGNPIEFEKGYYCKYCKKTWPQSSFRNSQQFGAHCSNCSRKPKGELEELISIKKKLSKKKSKEGNYYQEEDGAVPYWDMNRYNNNNNNNNGINNNNNNNNNNNNNNSNNNGSYNNNNSNNNNNNNRIEPIVNNNINNFNSINNNNSNNNNNNNSTSQNAPLLQRLIHVVENQLLEPNELSSIREDIDIMKNDLILRKKKRIAQLNDLKQKANNDVQILKANIEKGSNQRSNESKSFITDLKQEIDKRLNQYTHIYIPPDHHLVPSSTNYLSIDSLQNSSSSNNYGTIHNSNNNNNNNNNNNKRSLVNLSPELIHSPLKKPMVGGYRDEQGMKHFSIDGDNLSLPSIS
The following text describes a protein:
Function:
Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein. Required for the formation of complete GPI precursors CP1 and CP2; Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGFWGRNSFEADKKHILVTGGSQGLGKAIAKELVLRGANVTIVARTVTKLQEAVAELSDSKIHEDQQVSFESVDLTSYESVHSMIERLPFCPDHVVHCAGSCIPGFFTELDPSVFEKQMRQNYLASVYVCHAAIRRMKEISPSYSRRILLVGSLLSSLPIIGYSAYSPVKAAVRNLADSLRQECILYDIEVSVYLPSTILSPGYEQENTLKPELVLQMEGMDSVQTCEEAASHCMTGLDRGDFLIANESTGHLMKNHCRNSSPHDNPILEYLFALVSLLAWPFYRRKLDSLVYQYALEKGYRQPSSSRNSWIFTLLLTFTQLTIFYLSLNCLIENPYRMLRNTFPIWFIMQTLQIYIQSPRPPLTPKRLLAGAASMLIGSLLISFILVAFGAPLLHDFHLTYFCALTLSVFTVYPLASTLAFNTEQWQRFLTLKSFNVIGSMQLRSWGPIIGAWFGAFPIPLDWDRPWQAWPITIVIGAFLGYAFAAIVGEILQ
The following text describes a protein:
Function:
Plays a role in hair follicle differentiation.
Subcellular Localization:
Nucleus.
Sequence:
MKLEVFVPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGPSAQDGPEATDDSRTQASAAGPCAGGVGGGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRTTVSASGLRPEEAPPGPAGTPQPAPAARSSPIARSPARQEERSSPASKFSSSFAIDSILSKPFRSRRDGDSALGVQLPWGAAPCPPLRAYPALLPAAPGGALLPLCAYGASEPTLLASRGTEVQPAAPLLLAPLSTAAPAKPFRGPETAGAAHLYCPLRLPTALQAAAACGPGPHLSYPVETLLA
The following text describes a protein:
Function:
Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.
Sequence:
MESLDQISNVKPAKPPPKRFVKNQIPDSILNDASLNAAIALLPSNYNLEIHKCVWRIRSTGTKRLALQLPEGLLMYSLILSDIFTAFAGVTHCFILGDVTYGACCIDDLSALALGADLLIHYGHSCLVPIDATKIPCLYVFVEIKIDVECLISTIKLNLKDYKSVILAGTIQFASAIREAKPELERLGLYALIPQSKPLSAGEVLGCTAPKISSNSMVGGGSETVVVFVADGRFHLEAFMIANPGISTFRYDPYMGKLFLEEYDHRGMKEVRKGAIQMAKEARNWGIVLGTLGRQGNPRILDRLEKKMREKGFSYTVVLMSEISPVRIALFEDCIDAWIQIACPRLSIDWGEAFKKPLLTPFEAEIALGDLPGWWEKSAGCGSDDLCSGCTNGGDYPMDYYAQDGGEWNSAYVKKATRPVRRNVVSSGGYGAAL
The following text describes a protein:
Function:
Lipid-binding oleosin involved in tapetum development, especially for the physiology of tapetosomes (By similarity). Also implicated in the formation of pollen coat (By similarity).
Subcellular Localization:
Secreted, extracellular space, extracellular matrix, pollen coat. Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface.
Sequence:
MLSFLIPVVQFFQVVIAAVASVVFLVFAGITFGASIVGLTIATPLFVIFSPILVPATIATTFLVGGATAAVALGVTAFALILWLFKHRIGVKPKNNPAPKGAPTKADQPGASGGASGDKPGEMSGAGGPSGDKPGGASGGGDKPGGASGGGPGGASGGASGGASGGASGGASGGASGGGPGGASGGGPGGASGGGPGGASGGASGDKPEGAPGDKPGGAWGGKPGKKPGHKPEGARGGKRLAWW
The following text describes a protein:
Function:
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
Subcellular Localization:
Cytoplasm.
Sequence:
MTAPRDPDALIRRAGRPNPDFDQHFLIDDRVLDRIPTYADGFDRGHVLEIGAGTGALTDRLLSVADRVTAVERDESYASFLREEFADAIAAGDLDVVAGDALAVDLPAFTCAVSNLPYGVASEVTFRLLPAGKPMVLMYQLEFAERMAADPGTSEYGRLSVATQHYADVSIVETVPAAAFDPQPRVESAVVRVTPRDPDYVVADEAFFLSFVKALFTQRRKTTRNAIRNTAHISGLDDPDAVVAAVDDDVLGTRPGSLSPATFAALANVAWGVETAPGPDPQ
The following text describes a protein:
Function:
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Sequence:
MEGCMGEESFQMWELNRRLEAYLARVKALEEQNELLSAELGGLRAQSADTSWRARADDELAALRALVDQRWREKHAAEVARDNLAEELEGVAGRCQQLRLARERTTEEVARNRRAVEAEKCARARRGSQAAELERELEALRVAHEEERVGLNAQAACAPRCPAPPRGPPAPAPEVEELARRLGEAWRGAVRGYQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQERRAALEQRLEGRWQERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMSLSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQDPKLELQFPGTPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQARTPTLASTPIPPTPQAPSPAADAEIRAQDAPLSLLQTQGGRKQAPEPLRAETRVAIPASVLPGPEEPGGQRQEASTGQSPEDHASLAPPLSPDHSSLEAKDGESGGSRVFSICQGEGEGQIWGLVEKETAIEGKVVSSLQQEIWEEEDLNRKEIQDSQVPLEKETLKSLGEEIQESLKTLENQSHETLERENQECPRSLEGDLEELKSLEKENKELLKDVEVVRPLEEEAVGQLKPTGKEDTQTLQSLQKENQELMKSLEGNLETFLFPGKENQELVSSLQENLESLTALEKENQEPLRSPEAGDEEALRPLTKENQEPLRSLEDENKEAFRALEKENQEPLKTLEEEDHSIVRPLETENHKSLRSLEEQDQETLRTLEKETQQRRRSLGEEDQMTLRPPEKVDPEPLKSLDQEIARPLENENQEFLKSLKEESVEAVKSLETEILESLKSAGQENLETLKSPETQTPLWTPEKINQGTMKPLEKEIQEPLESVEVNQETLRLLEEENQESLRSLGAWNLENLRSPEEVDKESQRNLEEEENLGKGEYQESLRSLEEEGQELPQSADVQRWEDTVEKDQELAQESPPGMAGVENEDEAELNLREQDGVTGKEEVVEQGELNATEEVWIPGEGHPESPEPKEQRGLVEGASVKGGAEGLQDPEGQSQQVGAPGLQAPQGLPEAIEPLVEDDVAPGGDQASPEVMLGSEPAMGESAAGAEPGPGQGLGGLEDPGHLTREEVMEPPLEEESLEAKRVQGLEGPRKDLEEAGGLGTEFSELPGKSRDPWEPPKGGEESEAEAPRGAEEAFPAETLGHTGSDAPPPWPLGSEEAEEDVPPVLVSPSPTYTPILEDAPGPQPQAEGSQEASWGVQGRAEALGKVESEQEELGSGEIPEGLQEEGEESREESEEDELGETLPDSTPLGFYLRSPTSPRWDPTGEQRPPPQGETGKEGWDPAVLASEGLEAPPSEKEEGEEGEEECGRDSDLSEEFEDLGTEAPLLPGVPGEVAEPLGQVPQLLLDPAAWDRDGESDGFADEEESGEEGEEDQEEGREPGAGRWGPGSSVGSLQALSSSQREEFLESDSVSVSVPWDDSLRGAVAGAPKTALETESQDSAEPSGSEEESDPVSLEREDKVPGPLEIPSGMEDAGPGADIIGVNGQGPNLEGKSQHVNGGVMNGLEQSEEVGQGMPLVSEGDRGNPFQEEEGSALKTSWAGAPVHLGQGQFLKFTQREGDRESWSSGED
The following text describes a protein:
Function:
DNA helicase required for crossover formation, complete synapsis of homologous chromosomes and bivalent formation during meiosis. Is specific to recombination events resulting in interference-sensitive crossovers (class I meiotic crossover).
Subcellular Localization:
Nucleus.
Sequence:
MDTHTLKSVSDLPGNFRSAFSFRYFNSLQSECFPLCFHSDINMIISAPTGSGKTVLFELCILRLFSKSISKEGSFLHAKGALKTVYISPSKALVQEKLRDWNQKFNSWGISCLELTGDNETYSTKNIQDADIILTTPEKFDAVSRYRVTSGGLGFFSDIALVLIDEVHLLNDPRGAALEAIVSRLKILSSNHELRSSTLASVRLLAVSATIPNIEDLAEWLKVPTAGIKRFGEEMRPVKLTTKVFGYAAAKNDFLFEKRLQNYIYDILMQYSKGKSALVFCSTRKGAQEAAQKLAQTAMTYGYSNPFIKSREQLERLREASPMCSDKQMQSYILQGVGYHNGGLCQKDRSLVEGLFLNGDIQVICTTNTLAHGINLPAHTVVIKSTQHFNKEKGHYMEYDRSTLLQMSGRAGRPPFDDTGMVIIMTRRETVHLYENLLNGCEVVESQLLPCLIEHLTAEIVQLTISDITRAIEWMKCSYLYVRMKKNPENYAIKKGIPKDRVEKHLQELCLQKINELSQYQMIWTDTDGFVLKPEEPGRLMTKYYLKFETMKYIINTPTSYSLDEALHIVCHAEEISWIQLRRNEKKTLNDVNADKEGRLRFHINDNKGKRKKRIQTREEKLFVLANDWLTGDPSVHDLSMTQDANSICSNGSRIARCMKEYFIYKKNYKGTLSSTLLAKSLYQKLWDDSPYLLKQLPGIGMVTAKALHSMGVRSFEALAEADPRRIEIVTGRKYPFGNTIKESLSSLPPKVEIKVEEVDCQKQGISKLAVTLSRVSQPLQSTKRHYADLIVGSEEENLIHFHEKIRMEDFSSPYSVTVLLERPHQQTKVTVKADLIFEEYIGIDLHETLLLKKANNNKVNYKSENRMPQYYPPMASACIADDDNPVTSGPSNRKDKKDDMPSFKLIDDDSEEEKEPYVTMEEDDCVIINEHTVFDHIREKAKCFPSLNPLNPTSSPASGKSILKRKSLVENNSPELDPLFQYDSVFDLPTNTKDIKQSAQQITSPGYASFAEKTETERPFSDETIFNYIRKRSKNSPALATSKIENPITISSQEGRNAEISPYRTYGLLVSPATKIPRITSDAPSEILSFDISMVKRSDTSLEQTKGFCSTLAGKSNVSDSFLGFKSIFSFL
The following text describes a protein:
Function:
Induces sprouting in endothelial cells through an autocrine and paracrine action.
Subcellular Localization:
Secreted.
Sequence:
MRPLCVTCWWLGLLAAMGAVAGQEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYTFIVPQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPNPNTFH
The following text describes a protein:
Function:
Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B.
Sequence:
MATCAEILRSEFPEIDGQVFDYVTGVLHSGSADFESVDDLVEAVGELLQEVSGDSKDDAGIRAVCQRMYNTLRLAEPQSQGNSQVLLDAPIQLSKITENYDCGTKLPGLLKREQSSTVNAKKLEKAEARLKAKQEKRSEKDTLKTSNPLVLEEASASQAGSRKESRLESSGKNKSYDVRIENFDVSFGDRVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAHISLLHVEQEVAGDDTPALQSVLESDSVREDLLRRERELTAQIAAGRAEGSEAAELAEIYAKLEEIEADKAPARASVILAGLGFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYRGDFETFIKSKQERLLNQQREYEAQQQYRQHIQVFIDRFRYNANRASQVQSKLKMLEKLPELKPVDKESEVVMKFPDGFEKFSPPILQLDEVDFYYDPKHVIFSRLSVSADLESRICVVGENGAGKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKFPGRPEEEYRHQLGRYGISGELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGRALNNFRGGVILVSHDERFIRLVCRELWVCEGGGVTRVEGGFDQYRALLQEQFRREGFL
The following text describes a protein:
Function:
Involved in the transport of siderophore enterobactin and so has a role in iron homeostasis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MALDDISAVPKGALDTDPAVERPPPLLDADRSDSERLQPGVKRAEMLRKGWTRQGLIIAFTGLFLATLSINFGDYSTQVYVPYATSAFKQHSAMSAARVVGNITRIAAYPIIAKLGDVFGRAEMFILSIVFQAVGYAIYAGCKNVGQYIAGGIFEAIGSTGFGLTQQVFVADVTNLINRAVWSTLPDSLTVIPALYLGTEIAEAVLEKNEWRWGFGMWAIIEPVCSVLLVGTMLYYQKRARKDPSPAEFASEPTERNVDDGWWKRIYNLVWVQLDAFGAILLLLGLSLFLVPLSLTGSGNSDDWHRGSFIAMLVLGVVIFVAFLAWDTWCAKKPFIPYRMIKNRTVAAACLLGILDFFHYSVFSVFFTSYLQVAAHHGAGPATRIDNSLRVAFQVAGIFAAYFMKFTKRSQVWVFTGVPLCVLGMGVLLYLVDMGEGRVGNEAAFVTAKSLIGIGRGFYQTASQVSVQAKVSRGEVSVVTAVFFAAMSIGGAIGTSVAGAIWRSTLPPKLAQHLPAELKDQAQAIFGSIVVAQKYEVGTPARDAIDMCYRQSQRMLAIAALAALAPMLIIMFFLENVPLTDETTLIELHGNREAVKKNHSGGEGKEARS