lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
Subcellular Localization:
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Sequence:
MSAKQDGSTAESRKAPHSYRERVNSTVELAALVYRPLTASGALLSILRGKLYRRRSVRNVLDVVAVRSISGGQGHSAESKVRVEYLTPAEGNANGNSISNISAAPCADIRGSSDTAATSSSPSTPAQPTLLEGRCKMCLLDPTVLKATELCPDPASAAQHCTPVFLLGAAVVGSHVTRQLEAAVQAGQLSRKAADLLQQLHERLAGGPSSVSLTEDTDGSEQPQGLPRAAAAPPPPSNKRRASYTGAVEVTFTPRAVELNYQAYTMSELLSMVLPLREHADLVALSGFEQVGHIAHVNLSAAHLPYADIIGQVILDCNETVSVVVNKVDAISSVFREFKMDIIGLRRRTDSVDGNVVAGADLDDAGEAGGSLTAAERQAIALEALSPTYSLAEARVHRLLTATVRQHGCSFRVPYNRVYWNSRLSFEHTRLVDRMRPGDVLFDVMAGVGPFAVPAAKKGVQVFANDLNPVAAQYMKVNAELNHLPANALHVFNMDGRDFLNSVLFTSVTRAADASLPGHLCTGRRHVTMNLPAIAVEFLDVFQPLSSTCAPASEQRCNASAAAVVNERWNHLPAHVDPNAIDRRTLFHVYCFSAAEDLITDAVRQVEVNLGYTLPPENIEETLMVRDVAPTKRMMCVSFTLPPAFWKNLLASRPGQGGEPGGAHAETASTLVEVEQAAKKARPDKM
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Sequence:
MNVPKARLLKVAELSAKIFDQNFNPSGIRTGSKILNERLKGPSVASYYGNPDILKFRHLKTLYPDIEFVDLEEQYRLSMVEAKKRRGKGAPKKMKKDAAATAKGKGKKKK
The following text describes a protein:
Function:
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MDDRSLKLAEDFVSARYIDAGRESLRSTARILRSILAQRCCPDEGLTDAAIELILRQLSLMDTNNFARHVGGGEREGRVVSALVRMRHFHLTHGVGRSGDLFSEQPKAAGSSLLYKITNVLMLDLIRQAGAPSTAAAVVVPMATGMTLALVLRCVAKTHMKELMKEAEAVQLQRTATKDSTSAASAAPAQEPPMSEADRGRHGRTSLPVPATPRYVIWPRIDQKTALKCIDAAGLVPVPVQLRPAVPLARSAALCASTNRDSLDRGQDSIGSPSTPTSSSSLFLECHVDDVAAAVSAVGGPSQVVCVLSTTSCFAPRLPDNTVAIAQYCKKAGIPYVVNNAYGVQSRRIMTRLDAAQRLGRVDFVVQSGDKNFLVPVGGSIICSSDKERCKAVTALYAGRASMSPIVDLFITALSLGRRGMQALWSDRYKCRARLIRQLRVFARERREVLLVDDTDDDKADEDTVGGSQKTSNAAAPRNDISVAVTMRAYGLPAAEASSSGAQRGSEQVGKVTNWAAARALGAQLFRSAVTGPRVITPAPSTPTTIAGCTFRNYGMHQDREPPCPLLVIACGIGMSESEGDALMARLRDLWPVPT
The following text describes a protein:
Function:
Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.
Subcellular Localization:
Cytoplasm.
Sequence:
MVISMEMKNVNVGLFGHIDHGKTQLAKQLTEIASTSALDKPKESQKRGITIDLGFSSFTLDRYRITLVDAPGHSELIRTAIGAGNIIDAALLVVDAKEGPKTQTGEHLLVLDLLNIPTIVVINKIDIANDEEIKRTEMFMKQILNSTINLKNSKIIKISAKTGEGIGELKKELKNLLDSLDIKRDINSYLKMPIDHAFKIKGVGTVVTGTIHKGKVEVGDNLRILPINHEVKVKSIQCFKQDVSIAYAGDRVGMALMGVEPESLFRGCILTSEDTKLKVVDKFIAKVKILELFKYNLAPKMKVHINIGLLTVPATIIPYKIEKINDKEEPIILEEIKGGDSCYCIFKLEERVVVDEGDKILIMRLDLPPTTLRICGFGEVIDFGEVEVKKIVVKEGKVVKKKDKIYIEGLASSKTAGEKLIGGKVYIPDKNIWGVIKGTFGTKGALIAEFDEEVNGGEKVVLKRVRKWG
The following text describes a protein:
Function:
Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes the phosphorylation and dephosphorylation of NAD and NADP, respectively. Although it shows conflicting dual activities and is able to supply NADP, it seems that its physiological role is to prevent excess accumulation of NADP.
Subcellular Localization:
Cytoplasm.
Sequence:
MDMLEMALNIAKDIEKSVKPLIGWEKSNEVVKIGADGTPTKRIDLIAENVAINSIEKVCSAILISEEIGFKRIGKNKPEYVIVLDPVDGTYNSLKDIPFYSAAVAIGRIDKFADNLEELINNLKMKDLEVGVVRNIATGDTYYAEKGKGAHFLRKGEKKSISISNSSNLKDSSIGLFAHDISIDTLKFIKDRRFRRIRLFGSIALEMCYVAKGALDAFINVNETTRLCDIAAGYVIIKEAGGIVTDKNGQEVNLDLDVNSKVSVICSNEMLHKKLVGIFGNRWRIKPTNFGIISRIDNEESIEVADNVIKYLDSKGIKYELDSSTYNALKNRLTKKCDIISNIEEISHMISIGGDGTVLRASKMIEGNEIPMVCINMGTVGFLTEFNKDEIFSAIDSIICGSYKVEKRTKLMGFAKLSDGKQHILNDSLNEVVITTKNPAKMMHFEVYIDGSLVEDVRADGIIVSTPNGSTAYSLSSGGPIIEPTVEGFVIVPICPFKLSSRPLVVNANSEIKIKLLKKSTYVVIDGNTEFEAKKGDEIILRKSESNAYFVKGDNFYNKLKKLSLM
The following text describes a protein:
Function:
Required for vanadate resistance.
Miscellaneous:
MISCELLANEOUS: Present with 688 molecules/cell in log phase SD medium.
Sequence:
MIFKILCSLLLVTSNFASALYVNETTSYTPYTKTLTPTYSVSPQETTLTYSDETTTFYITSTFYSTYWFTTSQSAAIISTPTASTPTASTPSLTTSTNEYTTTYSDTDTTYTSTLTSTYIITLSTESANEKAEQISTSVTEIASTVTESGSTYTSTLTSTLLVTVYNSQASNTIATSTAGDAASNVDALEKLVSAEHQSQMIQTTSADEQYCSASTKYVTVTAAAVTEVVTTTAEPVVKYVTITADASNVTGSANNGTHI
The following text describes a protein:
Function:
Displays alpha (N-terminal) acetyltransferase activity. Catalyzes the covalent attachment of an acetyl moiety from acetyl-CoA to the free alpha-amino group at the N-terminus of a protein.
Miscellaneous:
MISCELLANEOUS: NAT does not require a binding partner for activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MEITEDSKRKINYQIRLATLSDIDQIIRINRSALPENYPYYFFVEHLKEYGQAFYVADLEGEVVGYVMPRIEWGFSNLKHIPSLVRKGHIVSIAVLEPFRKIGVGTSLLQNSLKAMKDTYNAEEVYLEVRVTNYPAISLYKKFNFREVKLLKHYYADGEDAYLMAAPL
The following text describes a protein:
Function:
Enzyme involved in the catabolism of H(2)CO(3) but that does not mediates the reversible hydration of carbon dioxide. Mediates complex I assembly in mitochondria and respiration (By similarity).
Subcellular Localization:
Mitochondrion membrane; Peripheral membrane protein; Matrix side. Note=Probably integral to the membrane.
Sequence:
MGTMGKAFYSVGFWIRETGQALDRLGCRLQGKNHFREQLSRHRTLMNVFDKTPNVDKGAFVAPNASLSGDVHVGRGSSIWYGCVLRGDANSISVGAGTNIQDNALVHVAKTNLSGKVLPTVIGDNVTIGHSAVLHGCTVEDEAYIGTSATVLDGAHVEKHAMVASGALVRQNTRIPSGEVWGGNPAKFLRKVTEEERVFFSSSAVEYSNLAQAHATENAKNLDEAEFKKLLNKKNARDTEYDSVLDDLTLPENVPKAA
The following text describes a protein:
Function:
Protein disulfide isomerase which associates with the unc-29 subunit of levamisole-sensitive nicotinic acetylcholine receptors (L-nAChR) to promote L-nAChR assembly in the endoplasmic reticulum at neuromuscular junctions; [Isoform a]: Promotes L-nAChR assembly in the endoplasmic reticulum at neuromuscular junctions.
Subcellular Localization:
[Isoform a]: Endoplasmic reticulum membrane; Multi-pass membrane protein; [Isoform b]: Endoplasmic reticulum lumen. Note=Ends with a KDEL sequence, which is an endoplasmic reticulum retention signal.
Sequence:
MSRILLLLAVLIGATSQKEVTIKNEKCRTCNFLVSTFDEGLKKTARHHFAGGDTAWEEKNLGKYKTSETRLIEVLEGVCKKSSLPNMDNFMGIAEIEFKCSTQLEKHEETIEEFYYNQQHNNMSNWLCVEQLKLCCPDGHFGKNCEQCPGLSEKADVCFGKGSCHGDGSREGSGKCKCETGYTGNLCRYCDIEYFEESRTVQGVVCKKCHEGCLGVCSSESSKGCSKCKNGWKLTEEGCADVNECQNESACTKEHEICVNTVGSFKCECKEGYKKDDEQNCQFDVEASPDRPFMPIDQQLKLIAFSSLIIIITFVVWHGSPVLYVLTGITIVALILVDLYVNPDTIPDEAKRFLGY
The following text describes a protein:
Function:
Required for the formation of actin cables at hyphal tips. Involved in establishment and maintenance of hyphal polarity axes. Stabilizes the localization of the formin sepA at sites of polarized growth.
Subcellular Localization:
Cytoplasm, cell cortex. Note=Localizes to hyphal tips and sites of branch emergence.
Sequence:
MSIPLPIRTSDGTGNLSSSPPKSNGLPRLSPSPSFVQKHSPRSSDTSGLRRSASHHNARQTFKQRRCKSQYPRDSPERHVEFILVASFHIDRGPIMEHQYPGPISSDEGMLAELMLPDQTHVRSQDWTIFFLPLDTGGEGEEDDLAGENNKRKGKRNRVRSSSGDEGTSADTNNESEVTEEEESSDEEDGGEGPPLMYVLNLVNTKQDNTVKRGAVVKAMAICTRHSFLHIYKPILLLALEDYFKNPYPETLETLYNAVNAMDLSPMPKLNLLERQILQATNSKDMFIEKFEQMVQQRAIEDGENDIDEDNPPSPRRGTAPRYTLPRDTHEFESKIIYNDIPIPVKVPTVIWPEIVGDFSLVKLIQIFSAPHAASPQPFPLHPHLTTSGPLTHPIIVLVNAMLTQKRVVFLGHNRPSGEVAEAVLAACALASGGILRGFTRHAFPYTDLTKIDDLLRVPGFIAGVTNPTFANHPEWWDVLCDLPTGRIKISNHIEPAPVTDGQLYFQQQSPVSASGPNADPTGDNLFMEDVLRSIANRYGENAIRAKWRAYITKFTRVAAAFEETVYGASNIYIIGPNEELSPDSPSGLQSDPGDPTTIRGHGYVWPDEASKQRELMASVSRIEGWRTTRSYYSFIQDIAAMYWPSRPIQKPDLHHHHDRLRTLKLSAYEAGAIYLAFAHAIKDYAGICQLLTVTPESQAGLFYLSMGLLHPDRNVREATADLLERIALHPAGRHFWAQLNRFAKTAYFRIKREKEAAGNSSPIVKSPSDSFGPQQSLVGVAISGVHSQGS
The following text describes a protein:
Function:
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Subcellular Localization:
Mitochondrion.
Sequence:
MLSKTVSKVACARPIWRRLYANSSNNVGSPESTTESKPKVNRFAKQYANQDQNRNRLQSGSNRTIPRDPIPSNEGPRKNSGNTNRQTSAKQNLEKLKQNRSQQIRSGQEKITRSGSANSGSSANSSSQPRAPLSQSAPRKRIQPKKIKKTVKKLVKIQLPPFITASNLATIMHVPLNDVFKKLEGLGFEDIRHNYILDRENAAMVADEYGIEVEVVEESGDDLFPAPIKPDLLVERPPVVTIMGHVDHGKTTILDYLRKSSIVSQEFGGITQHIGAFSVTTPKSKKRITFLDTPGHAAFLKMRERGAIITDIVILVVAADDSVMPQTIEAIKHAKKSGVPMIVAVNKCDKPGVNVEKVLGDLSSHGVDIEDYGGETQTVQVSGKTGLNMDKLEEAVITLSELCDFKAEPKGIHAEGWIIESEVVKGMGNVATVLVRRGSLKNGDIIVAGKTFCKIRGMKDENNKMVKIAGPSTPVRIWGWKDLPDSGDQILQANSEQIAKKVIDYRITRSQEIQATRDIEDINVKRLEEIKEAERLEKIAELKKAGLDASTLEKAEQDKKTIKCNYIVRSDVFGSAEAIKESIDGLGNEEVESVVISHEAGPPTDSDIELAKTFGATIFCFNMKVPKPIAVRADKEKVKVKEHNIIYRLIEDVTDELSSHLKPRVEIKTLGEVDIKDVFVVTVKKQKVKIAGCKVTTGSIKSSSQVKVLRNGQEVYCGKLSSLKHVKDDITEATKGKDCGIAFEKWQDFEAGDKIQVYEEILHKRYL
The following text describes a protein:
Function:
May play a role in regulation of apoptosis.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Located in the cytoplasm of spermatogonia and spermatocytes.
Domain:
The CHD1 helical C-terminal domain (CHCT) may bind DNA and nucleosomes.
Sequence:
MEASDGQGGEGDKPLEQVTNVSCLETSSSASPARDSLMRHAKGLDQDTFKTCKEYLRPLKKFLRKLHLPRDLPQKKKLKYMKQSLVVLGDHINTFLQHYCQAWEIKHWRKMLWRFISLFSELEAKQLRRLYKYTKSSQPAKFLVTFCASDAPERSLLADREDSLPKLCHAWGLHSNISGMKERLSNMQTPGQGSPLPGQPRSQDHVKKDSLRELSQKPKLKRKRIKEAPETPETEP
The following text describes a protein:
Function:
Nodal coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
Sequence:
MRANSPTQGISLKMHQARPLFLVTVALQLIGLGYSYQSEGDGAREVSNILSPVIPGTTLDRTLSNSSRKNDIPEGARLWDSLPDSSTLGESAVPVSRCCHNGGTCVLGSFCVCPAYFTGRYCEHDQRRRDCGALGHGAWTLHSCRLCRCIFSALYCLPHQTFSHCDLKSFLSSGARGSRECSIPSLLLLVLCLLLQGVAGKG
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MAARLAFQRRAARATAAALVGSFALVPTVAFAEASESRASAKKPIYDDDFDVVPSTPSFTSAETTKDVSSPAAATLNAPVTTKSSTRSGERTFTDSLIDVLASTNTPRGPTPTDRLAAQIRRARLFLYKQACVAEDAVNAGMSRAFDLEHSFTSTVAGLAPPRESGERLMPGLIYVLVSGMAGSIVARNRNVVLRGATPLAFGLGAAWVVLPVTMNNVSSLVWKYEQKFPAVADAHIRTREGIEKGIYMAKVHAEIAQHKVDEAVTSVRETVEGWVRKGK
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MMPVLSMSLFVTTSRHSRWIRENAILDIPVVRMVVRDTEPKYIPLEEKWRLVPSFLKVRGLVKQHIVSFDFFINEEIRGIMAANHLVTSDANPNFYLKYLAIRVGKPSSEEGFNQIHDKITPHECRLRDMTYSAPITVDVEYTRGNQKVIKRDLVIGRMPIMLRSSRCVLKDLAEEALARVHECPFDPGGYFVVRGSEKVILIQEQLSKNRMMIGRNSNKDLQCEVLSSTTERKSKTYVLVKKGKYVLRHNQLSDDLPVAVVFKAMGIESEYDIISSVGSEERFVASMGASLEELNTLKIHSQQHALSFIATKVKVRKFGFGFGSQQTTVPVAKDHEAMDFLSSAMICHIPCTDGDFKMKAIYLGLMTRRFNSELKKVADHSLAKTLAAPLDIVRHMRQDLITNQIVTALASGNWTIKRFRMERIGVTQVLSRLSYISALGMMTRINSTFEKTRKVSGPRSLQPSQWGLLCPSDTPEGEACGLVKNLALLSHITTDCDEGPVLRLLFNAGVHDIRNVHFSKIHLPNQYLVFVNGLLIGTTIDHKRVIKSVRAVRRSGLLSEFVSVATSILQRSVYVSCDGGRLCRPYLIVENGKALLTNEDVKNVKEGKLVFEDLVDKGIVEYLDVNELNDAFIAVYEKDINQETTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGSIAYNQQLRIDSIMYLLCYPQKPMVKSKLVAMSPITLFSKINRVKLELFLDLPMTHIVAHLRACRLLRSSLSCSKCNVPCVEYQKVTPSWPGCGWRCPSCYCNYSALTGSWFARMRLDIRPLFRMIYSFCWEQASLRSLQHELRTPDGSTLSSKSFVDYHSFFREICWLDNERQPKIGGPGTVVEIDETAFSKRKYNRGKRMAAQQWVFGGVERGDKTKLFAIPVAQRDANTLLPLIAHYIAPGTEIQSDCWAAYRRIESIGHKYKHLTVNHSVTFKDKTTGAHTNGVEGMWQKLKLGHKRRFGTHRTQLPSHIATAVFFIRHELEDRFEAFLKATIELSNFDKLPAGQNGIIAVMSYSGYDIEDALVLNKASLDRGYGRCLVYKHMKATARKYPNQTYDRLMGPALDPKTMKPIWKHGVLDQEGIVFTGARIYSKQTLINKHMPMVTGGDASEAAQCVQYKDVSQSYKNPVPSYAERVLLTSNEEDAHLVKVLLRQTRRPELGDKFSSRHGQKGVCGLIAAQEDMPFNELGMVPDMIMNPHGYPSRMTVGKLMELLSAKNGVLGGRFHYGTAFGGDQVADVCEELASRGYNYMGKDMLTSGITGQQLSAYIYFGPIYYQKLKHMVLDKMHARSRGPRAALTRQPTEGRSREGGLRLGEMERDCLIAYGTSMLLMERLLVSSDQFTVEVCATCGLLGYKGWCQHCRSSQSLASIQMPYACKLLFQELQSMNIVPRLELAKSSA
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MNYPSNPNPSSTDFTEFFKFDDFDDTFEKIMEEIGREDHSSSPTLSWSSSEKLVAAEITSPLQTSLATSPMSFEIGDKDEIKKRKRHKEDPIIHVFKTKSSIDEKVALDDGYKWRKYGKKPITGSPFPRHYHKCSSPDCNVKKKIERDTNNPDYILTTYEGRHNHPSPSVVYCDSDDFDLNSLNNWSFQTANTYSFSHSAPY
The following text describes a protein:
Function:
Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.
Sequence:
MARNLSLKSTQKLLSGYEIPILGYGVYQTPTNVAENVTVEALKLGYRHIDSAAAYKNEKEVTAAIAKAGLSRSQVFLTTKIPPRANGYEAAKKSIEDSLKQANTEYFDLILIHAPYGGKEGRLGTWKALVEAQKAGKTRSIGVSNFGVHHLEELQMYISSGGGGQIDVGQYELHPWLARPDIVDWLRKHGAVVQAYCPIVRNQRGDEPVLKELGKKYGKSAAQVLIRWSLQKGFVPLPKSVTPSRIKENAEVFDFELTEEDMAKLETGKYEPCAWDPTVEKD
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MAHIQSNKSVSGTATAADEVKPAATTFHDFLGKGYPQDSSPGMSGRVVLPSEASPSASVSLGASSGGGRGPISTTSDLGSERVVGNHFEGVPFYGLRGELSGPETSNRLLGTKRSNSDSLMGSTRDKFAMLRSDALESSHMQKLLRNAGGERRGRPQDQEMSFVMHPMRPLHASLISQPSATGRTDVNASKWDRVIPVNVGPTLQYPPRASHVLPFGYQSSSNRFADANAGPSNISQAADEGSRTGIKGSGILSSINASGGISDRSLSGVPLSGAKQKSTLHFSDLESSNPCRQGSSPAGSQMTIFYGGQAHVFDNVHPNKADVIMSLAGSNGGSWSTTYAPKPAARPSTGENYSPKAENETTKGNNLALIREFHGRSSGKAGFTHGFGSGDHISIPQGVLRGVSTTKEAKTAVQVAENVTDEKRDM
The following text describes a protein:
Function:
Negative regulator of transcription elongation.
Sequence:
MDDIDFSINDFPINNNVDVLFSHSEFNDQLGQNIPKRENNPSSYSGDVTRCICGSATDNGETFVQCDGCDNWQHASCMGLKSDALPEKYYCELCRPDLHPELVYRQKQYQQVDILPQETTSDSLVNEFLNTEQLVDDNSRKRKANDFTPEGTMFPLGIAPVNTVADPVPSIPDSIQVFAPTQTDLPVPPPPSVSDMTSQDIVQNSDTLPSYVNNKRSKSNPKPTSTSAPTPAMDRDLQEFTNIEEIPNKVRQSVAKAWLSALKSMVEKCKTESANLKFPDLVEFALQLERTMFIELSYKIDGNAIPNKAYRDKFRNIKFNLTDDRNPHLRASLFKGEITPVQLVHMTSEEMANPDLKVFAEQIRQQSTENTILKEHHIPKPRKYEDGETEGDKDLKEEMSPAKSGTQKRSEQPYEPSRVGSPESESQQKENISSEGSRSDGQSAADSSKEGNSRDASSQPLTPKVSHKETLATVNPADLVEIDDPNIADILSDDGSTQTPPYSPTDHSPLFLNENAIWEGRIKMASVAEFPAKGIQVAGSLMDSTLTNEILSSTASLDGRISMESTLKYLQALQHSPSKDILAMVFLPTNSDTHGFDTLFDYFLKRNRYGVLRSKSPKVKDAYIVPLMPSPGKPPEILKYLPNSSFPADFKERVLLGLFIINKTNTVPVTRDGNFGKDTGASSVSQQNTPSVAPKAFNNPPSLVPTGTSITSDSSSSSHVSDVMTLFTPADCHFLKMLLETDQQIRANPSLAFNPSFLQKLVAEHIKLAHYPQLS
The following text describes a protein:
Function:
Required for the use of extracellular DNA as a nutrient.
Sequence:
MAFKIWQIGLHLQQQEAVAVAIVRGAKECFLQRWWRLPLENDIIKDGRIVDAQQLAKTLLPWSRELPQRHHIMLAFPASRTLQRSFPRPSMSLGEREQTAWLSGTMARELDMDPDSLRFDYSEDSLSPAYNVTAAQSKELATLLTLAERLRVHVSAITPDASALQRFLPFLPSHQQCLAWRDNEQWLWATRYSWGRKLAVGMTSAKELAAALSVDPESVAICGEGGFDPWEAVSVRQPPLPPPGGDFAIALGLALGKAY
The following text describes a protein:
Function:
Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=In mitosis, assumes a diffuse cytoplasmic distribution probably as a monomer, before reversing back into a punctate nuclear surface localization at the end of mitosis.
Sequence:
MPSSLLGAAMPASTSAAALQEALENAGRLIDRQLQEDRMYPDLSELLMVSAPNNPTVSGMSDMDYPLQGPGLLSVPNLPEISSIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSEDDPILQIAIDNSRNILYTRSEKGVIQVYDLGQDGQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQMTAGVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPTTLPPPSNVGPILGSPVYSSSPVPSGSPYPNPSFLGTPSHGIQPPAMSTPVCALGNPATQATNMSCVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFKSGNREITAIESSVPCQLLESVLQELKGLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTIIVAELQKELQEQLKITTFKDLVIRDKELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH
The following text describes a protein:
Function:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MADATLSNVFWGHSAGVLVLSASGLLWRSRSTESQKKLLKDDIVTLLWTPVGPKTHHLKVYQKGGTYVRFTGLKAQDVAQLKSHVESHFDRELEQEKVAASGGNWGDMKFEGPNLNFRTANASVMELPLEQISQCALPGKNEVELQFHEDDTVAGDEETLVEMRLYLPPGDGDDDVVTADDFRQQVLDKANIRSVMGKSIVDLDETIGTFLTPRGRYGVEIYGSFLRMHGKTFDYKIMYSNINRCFLLELPNGLNTAFVISLEEPIRQGKQGYPHLVLQLSKNDVHIDVNLSADEIKKYNGNIHERMSGALPQIVATLFKFIIGKKVYTSGKFKTHSGDRAVKCAVKAQSGVLFPLEKSFMFIHKPTTFIRYEEIEYIEFQRYAGQSGSSASRNFDLLVSCKSVGGEAAREYVFSAIDRREFPELSQFLTSKKLRIRNLKESHGAAAQAGSKKRDFNEYLEELGPEEGEIEDDEEDSDFGPGDASGSESSDFSDEELSGKDSDVDDADGASSKKDKKKKKKKSHKKLKAAEEE
The following text describes a protein:
Function:
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular Localization:
Nucleus.
Sequence:
MRSWVFLTALVAGLASSTWLSQVDAAACANICYTTELTGFGPGGTAGCSCSGSGATRAGSGSCSCGQCYEETNGAVIGYAINSDGTCTYGTDCGDCTYSSDASSSTSTTSSSANPSSTTATPSATSSTGSSTTTTTDAPSTTSPAATSDTTSSSSNTPTTSTSSSSNDNAGSAGSTATSDTSNNGLKTWQIALIICCGVLVFTVAVVSVLSCYCKARNRLYENEDEQADASYYQQQNPRLRQDVVGSVPNSTRSHARSGSSGSFSNELKPMLGVGLGLAPVHMRNSSGDLAGMAAGSYSNDRILSGSYPTDRRPSSSNSNSKRRRARDDSDSDEEQKTQHTIEVDDEASPPRRAKPRVAPGRNRKGFLENSQLTEKDRRHVRYKERELLQSIKENANDLAKLTSDTFDTHTQELDQMYESVCYPREANLDASNLDELNVAVAKQSQALGSSDLTKYDTTDLIRAAQEACAMESQAGDFDWNTLGLAAGACFRSAPEISFLFGLLDTEVVRKERKKAKRVQEDVNAQEAQPTEYTNKKDRKDAQARRLEVLQTMLNEGKRRESLFDVVVNPKSFTQTVENLFDTSFLVRNSSAEVGIDEATGLPYLENHEGMVDADMPASTQSIISITPAQWEQLARVTGRDEPLLGHRS
The following text describes a protein:
Function:
Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to centrioles and to the distal ends of basal bodies.
Sequence:
MQYPAATAEGLSGPLSGAYTLPAFKFQPRRESIDWRRISAVDVDRVARELDVATLQENIAGVTFCNLDGEVCNHCRQPVDPVLLKVLRLAQLIIEYLLHCQDCLSASVAQLEARLQASLGQQQRGQQELGRQADELKGVREESRRRRKMISTLQQLLLQTSAHSYHTCHLCDKTFMNATFLRGHIQRRHAGMADVGKQKQEQPLGEVLEELRAKLKWTQGELEAQREAERQRQVQELEMARQREMEAKKKFDEWKEKERSKLYGEIDKLKQLFWDEFKTVANQNSTLEEKLKALQSYSMTESHLGSLRDEESEERLKHAQEVQALQEKMEVQKTEWKRKMKALHEERAAERRQLQEENERLHVSLSQDQKKAAAQSQRHINALRAQLQEQARLIESQEETIQTLSLRKVEEVQEMPKAVATEEDSSEEELEASLEERQEQRKVLAALRKNPTWLKQFRPILEDTLEEKLEGLGIKRDTKGISAQTVRRLEPLLRTQREQIARSFREFPSLREKLNKEVSSRVKQRWESTTQPDGQPPVKSQRVTLATREVRPKTRTLTVALPSKPAEPSTPTLQGHSSHGPGLTQVSTPIPRPRVHGPSSTPVSPGSGLSSTPPFSSEEEPEGDVVQRVSLQPPKVLPRSAAKPEDNWGWSDSETSEESAQPPGKGSGGLASSGTLVQSIVKNLEKQLETPAKKPSGGVNMFLRPNAALQRASTPARKSQLSEDESDVEISSLEDLSQDLGQKGKPKPLSHSKLPEKFDVSPWSSGSRPRIPGW
The following text describes a protein:
Function:
Component of the glycosylphosphatidylinositol-anchor (GPI-anchor) transamidase (GPI-T) complex that catalyzes the formation of the linkage between a proprotein and a GPI-anchor and participates in GPI anchored protein biosynthesis. Binds GPI-anchor.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGLLSNPSDKQLSPLLLKFVGKQKVLSSLFYIGSIVWFVCLAYRQFNAGTYFSENALLPGLVHSNFKEDFLARQYVAAIKAEAERYPNGMPHAFIAAQFKQLGLDTFTHNFSVKYPLDENEVYSGKNVYGILRASRGASTECLVMSVPYRPPDSVLTGTNAGIAIMLSLAASFRAASYWARDVIFVVTEHEQLGMEAWLEAYHYTSSGSNSIDFGQLDARAGAIQAAINLEIPYEKISHIDVRMEGLNGQLPNLDLVNLVHRLFQQERFTTTLKEREDYPDPLSMEGWIYSASSLLTLMASQATGVPTGNHGLFHRFGIEALTVAGSYKRGWHGSNFLLMGRAIEGIMRSLNNLQERFHQSFFFYLLPATNRYVSIGVYMPPFGLMIGSMLLQAVALYISRKENPNEKQNWNFLNLGSFVLYSTICGLLFYSAPEKLTRFNRSMALGLSTEDVVFGGFCMLSVIHCILTSTVGVRMLSIQRLSANCVQCAILLLTSTLMYAVAMGNISLAVLTCFIISPVFSIAKPVSQRFLKYCRYAVLMLVHPLSLLFIATLIDTYRVFPEEINQPWKFFGKTHIAAQRALIYAVVDGTFYGNWLFFAVSTLYLPLWSLAWANLGNLSR
The following text describes a protein:
Function:
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MWKLQALVVHILLMGAILNTYFQHTLLPNLVPQKTMRELGLEPPADRLVVFVTDGLRAATFLANNGSDVPDLKDIYRQQGRIGISRTCAPTMTRPGHIAIFAGFHEDPAASLMHLCYNPGDFDTVFNRSRNMIGWAHSYIVGYFVKLSHGGAPLRFDSYMERDLPEKLTCDKWAFDKVENFLRNVDNVREWRNYKPAVFFVYLADMDIAAHRFKPLSKKFFAKLQYTQRGIRNTYELFERVFNDSRTAYLMTSDHGMNNEGAHGSGSPLEVETPLFMWGAGVKRDEIDAEANFPEKPNISQVDQTQLAPLMSSLIGLPPPKNNLALMPVGYLNVSDEYQAVALHLNVLQLLSQAEILIGRHEKAIFYKWLPKFKELHIGVIDQYAAQFDILKSEGNLTDAMEFCKEYGKLAKKCLTYYNQYYQTPLIVANSMSYMIWFYCLLLQLTRLSKKEKMQRRGFMTVSTLILAMIGILLIAMMELQKVPHIAAFYLILPVGMLIMAQAERPVRGYWIFHPLWNFGFILVPAVLIMSMTFIIRHLWVLYGISVLLNNRRALRKPSIKLFIWLSLALIVTAILFMEQRTIKGLKTIPVKDYHVLYVSMVLAIIRPLILGHRHDPRVWTFNSLTLVVGAFGVYQYKFYESVSSYVYVVTWSFLFFAFLSIVYFAKSLPEARKRLELITINMITVLSLLTNSWGCLNFQIAITEFIFGLQIYEETKETKEIEDAKDEHTSLQNLKGFYRYGYMILLYFYVSFFLAGHWISSFLFKPTTARLFYPHFSLYIAGSLVLLKIFIPSVIFICALYAMVPFVRKNARSILISIFMISNAMGLYQYYFIRNRGSWRKIRMFLDQILLTHAVNFMLLLGISLAKIFLANTTMERPGQKRARTTRSNLAAAETEP