lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSSTSPPQQQQRDFISPGGPLPISFPDLSSLPTEQRLAHEQALLLQRLSQTELKPAIPLETIELLSSSFPTQRTTPPALHPLNHQPLSAANPHPEDARQFLKLVADFTPREYLELIEERNCLGACGYVLCPRKRRQYEGEYKIIMRTGNIAKTEDLNKWCSDACAVRALYVKVQLDNPSYMTDLETGKRVVKVELREEEEEKKKKKKPSSGEEEKAKDKATTSIKEAEDKVAADLARLDLNRKAEISDKAAQMQRDADALAVERGQGSGKLDRLLAGQGVEVTIREKPTTGPAKAPDHAKASSTSRKKNPQDAHRMVEGHKPRFGTDIRSQEAAKNDGSESESEDTDEDDDDINDYLSGRMQISM
The following text describes a protein:
Function:
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
Subcellular Localization:
Cytoplasm.
Sequence:
MNAHELWQRYQTYLLFDADTGLILDVSRMAFSDDFFASMEPAMQRAFDAMERLEAGEIANPDENRMVGHYWLRSPELAPDPAIAAAIRETVDRVTAFAADVHNGVVTAPRARLFRNVLVIGIGGSALGPQFVADALGGHGDRMRPFFFDNTDPDGMDRVLETLGADGLAETLAIVISKSGGTKETRNGMLEAEAAYRRAGLDFSRHAVAVTGAGSELDRTAEAGGWLCRFPMWDWVGGRTSETSAVGLLPAALQGIPIRDFLDGARTCDTLTRRRETLRNPAALLALMWHHATRGSGSRDMVVLPYKDRLLLFSRYLQQLIMESIGKELDLDGTVVNQGLTVYGNKGSTDQHAYVQQLREGTNNFFVAFIEVLKDREGASLAVEPGFTSGDYLSGFLQGTRTALSEKGRESLTITIPAITPRTVGVLVALFERAVGLYASLVNINAYHQPGVEAGKKAAGGVLALTGEALAFLRREGGTLSATEIAAALGRPEEAETIFRSLLHAAANPDHGVVMEAASPLTRSRFSAR
The following text describes a protein:
Function:
Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MATSNDVANGTKHEPYDIKMTPDHPKSLEDPSQGRRALEVQDAGYDMPESGLRLDEVDMSAPAQIKGENRLRQSQFLGHTSSGEQGAHRRGSRASRSDIEYDLPDDYVHLNELVIPSPVENPRGAPIYLHKPLEEAKDEEQEYKQDQRDQERKKRDSIARGEKPPEEEKKDVSTKKASKFATQLYTISYLILFSIFGTLARLGLQSITFYPGAPVIFSELWANVGGCVFMGFLGEDRMLFKEEWGTATYHHKIQEWKAKVKDEENGSGSSAVGQLPDLQAAKKAHAATKKTIPLYIGLATGFCGSFTSFSSFVRDTFLALSNSLPSPLNHPQDYSPVMAGTTSTVSRNGGYSFMATLAVIITTVSLCLAALFFGAHLAIFLEPYIPSFSFRKSRKYLDPFTVFLAWGCWLGAVFLAIFPPDRNDAPPEIWRGRAVFALVFAPIGCLGRFYASLYLNGKLSSFPVGTFAVNMFGTAIMGMAYDLQHVPLGGVVGCQVLQGIEDGFCGCLTTVSTWVVELSSLRRSHAYRYGMHVYGI
The following text describes a protein:
Function:
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
Subcellular Localization:
Secreted, extracellular space, surface film.
Sequence:
MDQSKAVLMERPPVYSELPIPSIPCLGGVKKLVCVVLVVVVLVLVLVGVLLMGLHMSQKHTETIFQMSLQDGSSTGAHGTGVATFHLDTGINSSASVVYDYSKLLIGTRPRPGHACYITRMDPEQVQSLETIAESVLSKITSDASRQDDSMKPVTDRSLLGTTIKVLCGSLPVYWA
The following text describes a protein:
Function:
Not essential for epidermal patterning and not redundant with STRUBBELIG.
Miscellaneous:
MISCELLANEOUS: Over-expression of SRF1B induces no obvious phenotypes while overexpression of SRF1A may lead to seedling lethality in both cv. Landsberg and cv. Columbia.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MRSMRSGRDNNICFLGFLSFALISLPSLSLALTNPDDVAAINSLFLALESPLLPGWVASGGDPCGESWQGVLCNASQVETIILISANLGGELGVGLNMFTSLKAMDFSNNHIGGSIPSTLPVSLQNLFLSGNNFTGTIPESLSSLKSLSVMSLNNNLLSGKIPDVFQDLGLMINIDLSSNNLSGPLPPSMQNLSTLTSLLLQNNHLSGELDVLQDLPLKDLNVENNLFNGPIPEKLLSIPNFIKGGNLFNVTIAPSPSPETPPSPTSPKRPFFGPPSPNASAGHGQAHVRSPPSDHHPSRPTPQGKEDSFTSKRIIWISILGAFSFVVLALVCLLCGRKCLRKREDSEQLSKPHLTSEYGRAREGSRSNASMLPPSNTFNKDKEARPKERVGGASKLHGGAERSVGSESKQESHEIDMNGNAMDLMHPSSIPPIKRVIAKATEPAEASLKRTTSKSHGPLTAVKHFTVASLQQHTNSFSHENLIGTGMLGSVYRAELPGGKLFAVRKLDKKSPNHEEEGKFLELVNNIDRIRHANIVQLVGFCSEHSQRLLIHEYCRNGTLHDLLHIDDRLKIELSWNVRVRIALEAAKALEYLHEICDPPSIHRNFKSANILLDDDIRVHVSDCGLAPLISSGAVSQLSGQLLAAYGYGAPEFEYGIYTMKCDVYSFGVVMLELLTGRKSYDKKRDRGEQFLVRWAIPQLHDIDALAKMVDPSLKGDYPAKSLSHFADVISRCVQSEPEYRPLMSEVVQDLSDMIQREHRRNDSNGDNQYTGRR
The following text describes a protein:
Function:
Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. Possesses double-stranded DNA cleavage activity in vitro.
Miscellaneous:
MISCELLANEOUS: Plants silencing TPO6A1 are sterile due to defect in male meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MDDSTDDDSYHPRKHYAYDRQVSSSRWRTSREYIRGPGPETHTTESAQDGQDPPAGVYSYGYFSGSGNDPQVQGHFVPEIQKYNPYVIFKGEQLPVPIWELPEEKVQDFHDRYFIAKDKSRVEARKTLNRLLEGNINTIERGHGYKFNIPKYTDNMEFNEEVKVSLAKAGKTISRSFCNANQREVASRTGYTIDLIERTLGAGLNISKRTVLYTNKDLFGDQSKSDQAINDICALTNIRRGSLGIIAAEKGIVVGNIFLELTNGKSISCSIGVQIPHRLDQIKDVCVEIGSRNIEYILVVEKHTMLNYLLEMDYHTNNNCIILTGCGMPTLQTRDFLRFLKQRTGLPVFGLCDPDPEGISILATYARGSCNSAYDNFNISVPSICWVGLSSSDMIKLNLSETNYSRLSREDKTMLKNLWQDDLSDVWKRRIEEMISFDKKASFEAIHSLGFDYFATNLLPDMINKVREGYVQVQEKKEPQDTEASED
The following text describes a protein:
Function:
Probable polyglutamylase that forms polyglutamate side chains on tubulin. Probably acts when complexed with other proteins. Appears to be dispensable for polar spindle formation in dividing embryonic cells, for cilia-dependent osmotic avoidance and for male mating behavior. Regulates microtubule dynamics in uterine muscle cells.
Sequence:
MGLLDSKLCMMILAVSVLIIDINFEARIGTFFDLRLRTSYFKKSSSPLLSHTDSEEDLNYLSKHEDKRPVAIVTGSYESAHTGHMMHIREMFEHTGYKIVTKNELSLDTKWDVMWHHEYSFTQEPFKTLIKNASPNQIVNHVPGSGFYTSKVQLATSDLSNGVPKAFQLPAEKSKLLEYAEKNPDVLWVQKDNTHRNIKIKSTNDMDLSKNNSFVQKFVDNPLLIDNKKFDIGIYTVVTSLLPLRVYIYDGDVLIRFCPEDYHPFDANNVDKYVVGDDYTPIWEINSLKKYFNTQKMSFKSTIDSYLGMQGMDTSKIWLQIRNIIGEVFRTQQTKMLMSLQNLKLNPQYFELSRFDFVVDDQLNVFLMEANMSPNLSSGHFKQNQILYEQVLMNIFSLTGISTPITKEADILFKSRTSEQNPLVNSRDINLPLKFCVENKCESCDEAPECQLCGHCMNTETRKILEQTFVENSNRKQMKRIQFDYENHHPLTKEDHLLTLWLSTKCQLDNTWC
The following text describes a protein:
Function:
Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.
Subcellular Localization:
Nucleus.
Sequence:
MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEMSLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGPKRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRPPEDFETPSGERPRRRAAQVALLYLQELAEELSTALPAPVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDEDFFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLPNHIMAPVWKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSVQREGLPEDGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSSPDMNETHPLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGAWELPGTPRKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVATLQVGSMQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLLPYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTIAAGDISGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPNPPKARTYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPNLDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGFSPTSHRLLPTP
The following text describes a protein:
Function:
TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.
Subcellular Localization:
Nucleus.
Sequence:
MDPSIMKLLEEDEDESMHSGADVEALSAALNRDIGGDPAALARPPESDTGVSMLGSSSASKQVLGQWQTSSEVENEQQIQQKEQKRHLQSSEQHSSGGELIQAGSVSQPQDEQINNQPQHDCPTIQQEASHSDDLQRQPEANLLEKEQVKKPEQNTIQASDIVEGRKQEVAQHSENQQQHLTQQSNSQQIASANIANMAVQHSENQQQHIVQQSNSQQIPTSNQANMAMRRTKAASSIPFHLLIPILRPHLDKDRSMQLQAIFAKLRNNEVSKEDFLRVIRNIVGDQMLRQAAQKVQVQLQAQAARGAQTNTNSFSLQSQASSQQLASSVPPQITGAQSFPALHSIPSSQSLKVTGSPPHQPYVPPLTFQAQPGTGLTAPDNSTQKPREVETKSDGKGAQSVQNYTSNTNITNPERDVSMVSLQPVNKQQHHAQLPQSSFSVSGATSSYNTHAYPRPSMSSSTSIRPQNLDSHARQVSVTPGAVSTQLRPTQSVSVINVPKYEQNPANEAKRQQVGSVTASQHNPIAWQLSANKDQKGNTFPSMAVKQELVDQSSEPPNKSHFASSESTLFGSAHVNQGNHALGSSSTTGTTQISGSVPSQVDQIVQLHSHISSATPPLGGATAKTPSKKPSVGQKKLFEAPGSSPPMPSKKQKTSGTSLDQSIEQLNDVTAVSGVNLREEEEQLLSGLKEESRASEATRRIVQEEEERLLLLKAPLQRKLSDIMLKCGLKNIGGDVERCLSMCVEERLKGLISYLIRLSKQRVDIEKSRHRFVITSDVRRQILLANQKTKEEWDKKQAEESEKLRKVNELQMDGNTGVDAEKDKEDGRPKALKANKEEDDKMRATAANVAARAAVGGDDMLSKWQLMAEQARQKREGLDGAPGKTASSKPLLSLGRSSREKQESEKKGSSAVSASGGTRRFGRKNALESHPKVARNVSLKDVIAALEREPQMSKSALIYRLYERLSSNSSAT
The following text describes a protein:
Function:
May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.
Subcellular Localization:
Nucleus.
Sequence:
MTHSLVCPETVSRVSSVLNRNTRQFGKKHLFDQDEETCWNSDQGPSQWVTLEFPQLIRVSQLQIQFQGGFSSRRGCLEGSQGTQALHKIVDFYPEDNNSLQTFPIPAAEVDRLKVTFEDATDFFGRVVIYHLRVLGEKV
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.
Sequence:
MASNISPAAFDKEQIFGMAEKEMEYRVELFNKMTQTCFKKCVDNRYKESELNMGENSCIDRCVSKYWHVTNLVGQLLGSGRSPM
The following text describes a protein:
Function:
Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B.
Sequence:
MEPPIEIDHSAVGDWTIVEIRGEVDVYTVPVIKQYMIERLADGHRRFVVDLRAVAFIDSMGLGVLVGALKRVQSVHGELKLVITDANTKQLFALTGLRHVFPIYDSVYQARRTS
The following text describes a protein:
Function:
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
Subcellular Localization:
Cytoplasm.
Domain:
The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.
Sequence:
MTASLSAPAIGILAVGAYAPAAVITNAHYATRLDTSDDWITSRTGIRERRHAAPDESSSVLGIRATQDLAGRFPGALDGVNLVICATSSPDAMFPSTAALIAGGTGLRGAAAFDVSVACSGFLYALSVGYGMIRAGLAKKALIVGSEVMSGAVDQNDRNTAILFGDGAGCVVIGEVPQGYGFQSFVLGADSAGGPHLYLRGAALRLPEGTEMGPHLTQNGREVFKFAVRTLGDSAEQAMRQAGKTTADIDWLVPHQANIRIIEAACERFGLPIERAVTNLDRYGNTSAASIPLALAEAQAQGRFKDGDQLLLAGFGGGLSWGAAALKWWSGPTGKQSS
The following text describes a protein:
Function:
Specifically catalyzes the transfer of a galactosyl residue to the hydroxyproline-linked saccharide on Skp1 protein (fpaA/fpaB). Catalyzes the formation of a Gal-alpha-1,3-Fuc linkage, leading to Gal-Fuc-Gal-GlcNAc-HyPro143-Skp1.
Miscellaneous:
MISCELLANEOUS: Not required for growth.
Subcellular Localization:
Cytoplasm.
Domain:
Consists of two domains: an N-terminal catalytic domain and a C-terminal domain, not required for activity, that is predicted to form a beta-propeller-like protein-protein interaction domain.
Sequence:
MEKKVEYIKENDKIVLMCNYGFRDMTLNLLKCFEKLSIDKSRYILYCMDDKAYQFFAEFKGIECQRFSRDDIINSSTSSTQLFHDNNTNDNKGIYSENAESYGDIGFRAICNEKPLVVLDVLKKGYNVLWTDTDIVWKRDPFIHFYQDINQENQFTNDDDIDLYVQQDDDDICAGFYFIRSNQRTIKFIQDSINFLNPCIDDQIAMRLFLKSQGINIKSKNILLSLSENDKKDKIRYRLLDKKLFPNGTNYFNLKITQRDNITPFIIHNNCIIGHRSKKDRFIEYGLWYINDDEIDINSNINNDDENNKEIKLFKNVLKNHTDIITSINSSDDGKLFTTSIDKSIKIWKFENTSGNDTDNGIFKVLKSKYIHKRGGIWSTFIFSSNNNNNNDYGFENLLTSSHDKTIQYWDNNLQVIQTFIGHTGIINQLIVIPNSSYFFTCSDDNTIRQFDLNNINFKRVFIGHNGWVSSIAINKNLNTLYSCSNDGTIRFWDINSGRCLNIIKGNQGGWIRKIIYNDNLNQLISGGNDGTIKIWSCDNLNNFNDNQYLLKINTNENSSINDLQFDSDTNLIYCAFENGSLKSFKLTSNNNNNNNNNNNNNNNTINYSLDKVYQGHLNSSINCIHISKSLNLLFSGGFDKQIKSWDL
The following text describes a protein:
Function:
Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moeities to galactomannans and their subsequent pyruvylation. Has a role in meiosis.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MGLPLRIFAGNGIGGWCLRLFLFGSLILLLRPLIFYSNTTMKKLKTEYPIYHRHLSALKRNFYYTMDAQLGGIRNVVLINRPCFAASDNFLTLMGQNWYLKERNINVLSDICFPLSNNAHDSLPTFNNGSDLFNPLYFAVLNAATPARFTFHLFNHVMDSVVPFDEAKKFKVRSFPINYAEYADDECQLALKKIRPIPDKYLVSTRVLSDSRYLELSGAVVAFAPDASSSLLFELADIKQHKKTSADILIFLSKDHNLPVSFYDNYKLKYTLHFWQPPSFPDSSTIDDQAKLLFDYVVSQVVKYPYFVTDIYQIHLLGVYLNLKHVYLLENDDVEDAYYERQWMQAFQRKNVVAVAEELQTALRIIEQWKQL
The following text describes a protein:
Function:
Extracellular signaling peptide that may regulate primary root growth rate and systemic nitrogen (N)-demand signaling.
Subcellular Localization:
[C-terminally encoded peptide 15]: Secreted, extracellular space, apoplast. Note=Accumulates in xylem sap.
Sequence:
MDATKIKFDVILLSFLLIISGIPSNLGLSTSVRGTTRSEPEAFHGGKFPAMKMRKLMAPNMEVDYSSDYYDGGSSSSTTSPSPPVPDYDDIYRRQGDVPSPGIGH
The following text describes a protein:
Function:
Involved in the degradation of glucose and galactose via the nonphosphorylative variant of Entner-Doudoroff pathway. Catalyzes the dehydration of gluconate to produce 2-keto-3-deoxygluconate (KDG). It is also able to catalyze the dehydration of galactonate to produce 2-keto-3-deoxygalactonate (KDGal).
Sequence:
METIKSVDIYELGSPGEKSSPWSSTILIVKLTSSNGNIGYGEAPTTFMTLPVKESMREVERVFKDQNYFNIEKNMREFYKHSFYLSRSMEATSALSAFEIASWDLIGKDLGTPVYNLLGGEYNSELRAYANGWYSDCLEPDDFVSRAKEYIKKGYTAFKFDPFRNNFDRIGNDGIKKAVDIVSAMRSELGENIDLLIECHGRFSTKYAIKVGQALDEFNPLFIEEPIHPEMELGLFDFKRYVNTPVALGERLLNKEDFARYISQGMVDIVQADLTNSKGILEAKKISAIVESFGGLMAFHNAFGPVQTAATLNVDYTLTNFLIQESFEDSWPDWKRNLFSGYRIENGHFKLSGKPGLGITADEKLMEKLIYDGMEEFNKNEPSWVVSGTYK
The following text describes a protein:
Function:
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Subcellular Localization:
Cytoplasm.
Sequence:
MLNNILQFLKERELYSQANFETELDNHLKEKKNNFYVGFDPTANSLHIGNYVLIHIAKLLKDMGHTPHIVLGSATALIGDPTGRIELRKILEEKEIVKNTKTIKKQIKQFLGDVIIHENKVWLEKLNYIEVIRELGAFFSVNKMLSTDAFSARWEKGLTLMELNYMILQAYDFYYLHKNHNVTLQIGGSDQWANILAGANLIKRKNNASVFGLTANLLVKANGEKMGKTSSGALWLDENKTSVFDFYQYWINLDDQSLKKTFLMLTMLDKKVIDELCNLKGPKIKQTKQMLAFLITELIHGTKKAKEAQQRSELIFSNQPDLDIKLVKTSTNLIDYLVETKFIKSKSEARRLISQKGLTINNKHVLDLNQIIEWKEELQIIRKGKKSFLTIKTVNS
The following text describes a protein:
Function:
This promotes the activity of RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MISANVEYPFTEPGKLQQWRYSVGDKFDKGSIIGIFNSSKNQSELNLISQYDGIIKSILINDTKKELNKGDELYNIEYCTHDIQFSGLCATCGRELTDTQESLSILHGHSHLTVSHKEAQRIGDINTKRLLMEKKLSLVLDLDHTVIHAVTEQGFNSSPEWRNKDKNKNGIHTITVNGPMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKERILSRDDGNGINFKSLQRLFPCDDSMVLIVDDRSDVWKKSKNLIQISPYVYFTDVVDSLHHEKQPLLQQKLKEQQEQQQQQQQQQQQQQQQQQNKETTETTEKTEKTETTEITEKTDLDNKENQENKTTTTTTTTTTTTTTDSNNTNENEKGNEEEEEESDKVDCHLLIILDKLQKIHRLYYESKDKGGSPHVIDLVEIVKKDILKGTYIVFSGVYPLGTPIQKQPLRWLAEEFGSVVQNDINNETTHVIAQRKGTSKVNKALSKGLKVISPQWLIESTRIWQMADEDDFSLPTDIDSPITATSSNGGSVVNDGTATSGGGSGKDAPLVEEDEETKANLEKVAANLITGGVLDALYNDDADKELEDFLDGESDADSQGSRSSNASANSSDYENDEDEDDDDEQNNQDNSTAAVVDNNNNNNNNNNNNNNNNNNNNNNNNNNNNVNDKEIVKNSSIGVNNISKKRKRGDLRSNSSSSSSSSSSSSSNGSISSKSNGHHSSSSSSSSNSSVSSGSSDDENDDSSSVNGDSSNANQDDNDDIANFLEAELDKFIE
The following text describes a protein:
Function:
Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis; Probable mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MDPEAGGPQIIKVTPLQQMLASCTGAVLTSLIVTPLDVVKIRLQAQNNPFYKGKCFVYSNGLMDHLCVCEEEGNRAWYKKPGRFQGTLDAFLKIIRNEGVKSLWSGLPPTLVMAVPATVIYFTCYDQLTALLKSKLEENESCIPIIAGIVARFGAVTVISPLELIRTKMQSKKFSYKELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEVLKKWFCVKSGLYEPTFMINFTSGALSGSLAAVATLPFDVVKTQKQTQLWIHESHKISTPLRMSTWAIMKNIVAESGFSGLFTGLIPRLIKIAPACAVMISTYEFGKAFFQKQNARRQQN
The following text describes a protein:
Function:
Cystine/H(+) symporter that mediates export of cystine, the oxidized dimer of cysteine, from lysosomes. Involved in cysteine homeostasis during periods of fasting, which indirectly regulates mTORC1-mediated signaling by supporting de novo CoA synthesis, the TCA cycle and amino acid metabolism during periods of food shortage. Important for maintaining autophagy, and for development and survival during periods of fasting.
Subcellular Localization:
Lysosome membrane; Multi-pass membrane protein.
Sequence:
MDFSTHRLTTLLLLLLATVALGNAQSSQLTVDSHDITVLLNSNETFLVFANGLLDSDVEVALGTDSEDHLLLDPATFVYPAGSTRNQSVVITGLKAGNVKVVADSDDANKEIVKDVFVRVTVAKSRALIYTSIIFGWVYFVAWSVSFYPQIWSNYRRKSVEGLNFDFLALNIVGFTLYSMFNCGLYFIEDLQNEYEVRYPLGVNPVMLNDVVFSLHAMFATCITILQCFFYQRAQQRVSFIAYGILAIFAVVVVVSAGLAGGSVIHWLDFLYYCSYVKLTITIIKYVPQALMNYRRKSTSGWSIGNILLDFTGGTLSMLQMILNAHNYDDWVSIFGDPTKFGLGLFSVLFDVFFMLQHYVFYRHSRESSSSDLTTVTDVQNRTNESPPPSEVTTEKY
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MKALCVCGGRGRRGVLFLPVQVEVSVRTRARPYYGNPQSPGEGRAGEGGRARVGLRMLHLCSDPAWIGSVSLRTAVVSTLLFLLNFRTLVSPDSALLQVSSLEKEEGGTSGVLADRFQVSVTFEDVAVEFTWEEWRYLDLGQRTLYRDVMLENYENLVSIGIPVSKPDLLFLLKRDVQNQEGKVRSGIYSDPVFEENTFGTKVSSLKQVISSEVLSDQKVGKNMVWDSKMKESGICSNNLEKKKDQQERQSRQVAIGAEISMNKVNVPQCNTFKRSFRLKSSLVAPQRRALQKILCKFKGLAMSFRKLPNICDPFFLGRSLYKYTRWKKPFRYHSDLIKLKGMYAREKLDELKPVTVRRSNFSVYQKIQKGKKYYICKKCGKAFIPKEMLPNHPKIHNTKKNLGYNEWRKVFSERRHFISYKRIHFGKTPFLCNKCEKFFGCRTVPNSHQKIHAGENFILCSECGKAFFSKEQLITHQRTHPKKKPFECDECEKAFSRKGHLVCHQRTHTGEKPFECNECGKAFSYKKSLVIHQRTHRGEKPFGCNECGKAFSWKESLITHQRTHTGEKPFECNECGKTFIIRQSLIKHQRVHTGEKPFQCNECGKAYTCNSTLIVHQRIHTGEKPFECNECGKAYTRKGHLVSHQRTHTREKPFECNECGKAFSHKTSLVVHQRTHRGEKLFECNECGKTFMEKNSLIRHGRIHTGEKPFECNECGRTFSFKDSFIRHQSIHSGEKPFECNECGKAFKLKKSLISHQSIHSGEKPFECNECGKTFSMRNNFRRHQRTHTGEKLCQCNECGKAYTCKASLIVHQRIHTGEKPFECNKCGKTYIWKGHLVSHQRTHTGEKPFECNECGKAFSYKTSLVVHQRTHRGEKPFKCNECGKTFIEKQNLIRHGRIHTGEKPFECSECWRTFSCKESLISHQSTHTGEKPFECNECGKAFSLKKSLISHQRTHTGEKTFECNECGKTFSIRKSLKRHQRTHTGEKPFECNECGKAYTYNSSLIVHQRTHHRENHLNVMNVETPLVIKEYLLFIKKLILEKNLLNVVSVGKPLDRRCTLFTIREFILERNHLNAMNVEKAIGRRDILFAIRELITERNLLNVVSKGKPLVRKEN
The following text describes a protein:
Function:
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
Sequence:
MITTLTCPRCRAETVWEGNPHRPFCSARCKTVDLAAWADEEYRIAGPEAPSDNDENDRE
The following text describes a protein:
Function:
Required for the solubility and assembly of the heterotetramer 3-ketoacyl-[acyl carrier protein] (ACP) reductase functional complex (KAR or KAR1) that forms part of the mitochondrial fatty acid synthase (mtFAS). Alpha-subunit of the KAR complex, acts as scaffold protein, required for the stability of carbonyl reductase type-4 (CBR4, beta-subunit of the KAR complex) and for its 3-ketoacyl-ACP reductase activity, thereby participating in mitochondrial fatty acid biosynthesis. Catalyzes the NAD-dependent conversion of (3R)-3-hydroxyacyl-CoA into 3-ketoacyl-CoA (3-oxoacyl-CoA) with no chain length preference, this enzymatic activity is not needed for the KAR function. Prefers (3R)-3-hydroxyacyl-CoA over (3S)-3-hydroxyacyl-CoA and displays enzymatic activity only in the presence of NAD(+)(H). Cooperates with enoyl-CoA hydratase 1 in mitochondria, together they constitute an alternative route to the auxiliary enzyme pathways for the breakdown of Z-PUFA (cis polyunsaturated fatty acid) enoyl-esters (By similarity). NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. It efficiently catalyzes the oxidation of estradiol (E2), testosterone, and dihydrotestosterone. Primarily an oxidative enzyme, it can switch to a reductive mode determined in the appropriate physiologic milieu and catalyze the reduction of estrone (E1) to form biologically active estradiol (E2).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MASQLRLRSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSEDGAPRGKHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDRVIAVNLKGTFLVTQAAAQALVSSGGRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIPLGHMGDPEDVADVVAFLASEDSGYITGASVEVSGGLFM
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MSSSKHSSVFNYSALFLSLFLQQMDQNSLHHLDSPKIENEYEPDSLYDMLDKLPPLDSLLDMEDLKPNAGLHFQFHYNSFEDFFENIEVDNTIPSDIHLLTQEPYFSSDSSSSSPLAIQNDGLISNVKVEKVTVKKKRNLKKKRQDKLEMSEIKQFFDRPIMKAAKELNVGLTVLKKRCRELGIYRWPHRKLKSLNSLIKNLKNVGMEEEVKNLEEHRFLIEQEPDAELSDGTKKLRQACFKANYKRRKSLGDDYY
The following text describes a protein:
Function:
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
Sequence:
MEMGKMLVVYMTLGYPNVQSFKDFIIGAVENGADILELGIPPKYAKYDGPVIRKSYDKVKGLDIWPLIEDIRKDVGVPIIALTYLEDWVDQLENFLNMIKDVKLDGILFPDLLIDYIDDLDKIDGIIKNKGLKNVIFTSPSVPDLLIHKVSKISDLFLYYGVRPTTGVPIPVSVKQLINRVRNLVENKLIVGFGLSSESDLRDALSAGADGIAIGTVFIEEIERNGVKSAINLVKKFRAILDEYK
The following text describes a protein:
Function:
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Miscellaneous:
MISCELLANEOUS: Present with 606 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Sequence:
MSNELRLEDNYVPTSDTLVVFKQLMKLPVTVLYDLTLSWFAKFGGSFDGDIYLLTETLDLLIEKGVRRNVIVNRILYVYWPDGLNVFQLAEIDCHLMISKPEKFKWLPSKALRGDGKPYVVKLQPAKFIENLQTDLAKIYHCHVYMFKHPSLPVLITRIQLFDSNNLFLSTPNIGSINKESLYNKLDKFQGKPLISRRPYYVAFPLNSPIIFHSVDKDIYARLVLQSISRTISERETIIFKPVQKIPVKSIHNIMTLLGPSRFAESMGPWECYASANFERSPLHDYKKHQGLTGKKVMVREFDDSFLNDDENFYGKEEPEIRRLRLEKNMIKFKGSANGVMDQKYNDLKEFNEHVHNIRNGKKNEDSGEPVYISRYSSLVPIEKVGFTLKNEINSRIITIKLKFNGNDIFGGLHELCDKNLINIDKVPGWLAGENGSFSGTIMNGDFQREQVAKGGLL