lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
DNA-binding protein that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In follicle cells, the complex plays a central role in the site-specific DNA replication at the chorion loci. During development, the complex represses transcription of developmentally controlled E2F target genes.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MASASTENGEELMNYGSNSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDSPELQDSKTTGQKGQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVETHGENWEIIGPHFKDRLEQQVQQRWAKVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKKTAWTEKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVERRSVNASGSDLKSSRTHLITLIKSGGISKCMNNMQHNKESGGEAVNKSENADGASVTAVKGGDLAQESQDDHQKGSNLAHLSMQHLIKLTMPRQTPIILKRTRKHIPETHHQAGCSSSETFNQEEAAGNARSRPPSSPVISPIKSLPFSPSHFLKSPCLTTFEDMDLRASTPVTKVYNRVGMEIKKEMETSSIETPHKSQLGPRTPTPFKKALAAIGKKRDGRRYEPSSPSSLVEDLAEIIHEEHLSNSLTANNSKMMGAADQNSTLSTEYNAQSPPHMKRARKSLLSTWSSNHPYNAGSAKRIQPFETETPSKFLTSPGDILKDTLCSEQDLPFDEGRKENRPFHNRRINKYRGGLTYDHVIDPKWARVACGKSRDQMFMEEQAYACLKNLSCISRSLNFEKQKCLVNSFDRFGSL
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome; Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSRKEALSQFINQIHGRPVVVKLNSGVDYRGVLACLDGYMNIALDQTEEYVNGQLKNKYGDAFIRGNNVLYISTQKRRV
The following text describes a protein:
Function:
Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
Subcellular Localization:
Cytoplasm.
Sequence:
MKKWQCVVCGLIYDEAKGWPEEGIEAGTRWEDVPEDWLCPDCGVGKLDFEMIEIG
The following text describes a protein:
Function:
May be involved (but not essential) in spermatogenesis.
Subcellular Localization:
Nucleus. Note=Localized predominantly in the nucleus of haploid round spermatid.
Sequence:
MGDSRRRSLGNQPSSEAAGRSEREQDGDPRGLQSSVYESRRVTDPERQDLDNAELGPEDPEEELPPEEVAGEEFPETLDPKEALSELERVLDKDLEEDIPEISRLSISQKLPSTTMTKARKRRRRRRLMELAEPKINWQVLKDRKGRCGKGYAWISPCKMSLHFCLCWPSVYWTERFLEDTTLTITVPAVSRRVEELSRPKRFYLEYYNNNRTTPVWPIPRSSLEYRASSRLKELAAPKIRDNFWSMPMSEVSQVSRAAQMAVPSSRILQLSKPKAPATLLEEWDPVPKPKPHVSDHNRLLHLARPKAQSDKCVPDRDPRWEVLDVTKKVVASPRIISLAKPKVRKGLNEGYDRRPLASMSLPPPKASPEKCDQPRPGL
The following text describes a protein:
Function:
Probable cell membrane receptor for the IGF-like family protein IGFL.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MGPSWLLWTVAVAVLLLTRAASMEASSFCGHLEYWNSDKRCCSRCLQRFGPPACPDHEFTENCGLNDFGDTVAHPFKKCSPGYCNPNGTELCSQCSSGAAAAPAHVESPGRTHKQCRKKPVPPKDVCPLKPEDAGASSSPGRWSLGQTTKNEVSSRPGFVSASVLPLAVLPLLLVLLLILAVVLLSLFKRKVRSRPGSSSAFGDPSTSLHYWPCPGTLEVLESRNRGKANLLQLSSWELQGLASQPLSLLLDELEVLEELIMLLDPEPGPSGSTAYGTTRHLAARYGLPATWSTFAYSLRPSRSPLRALIEMVVAREPSATLGQFGTYLAQLGRTDALQVLSKLG
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
Sequence:
MSAASLEPPTYLSSLQNNIRARPIPWEGAVRAGNITDDHLKKIKAVDKVRKEQRRQTIDGDIPGYVTLLAGGSSGKSVLESAARRSDIVQYILVLAADLINDAPSLSSALIAHPQPYKPFLPLLRHSTNAEDPIPLLTSNFLTNLVSTSITSSSKSTPQDEEALPQLYHYLSTLTQNQDSGLQDIGVQGLSTLLRTSRARQLFWAQRKETVDPLVEILRAAAGSKDSGSSTTLAGSSRGVDVGIAGGVGLQLLYRVLLVLWQLSFEGELIGDELQEDHEILQLYSHLLRLSPKEKTTRLLLATLRNLLSFNRTTLLPVAVFVRLPALLSTISGRHLTDPDLLEDLKYLSEMLDEYTKTQTTFDQYAAELQSGHLRWSPPHRNPTFWKENARRILDENSGALPKKLKEIISKSWENDKQVLAIACNDVGHLVKELPERRGQLEKLGFKTRVMELMADKDESVRWESLRAVGEWLRYTFDD
The following text describes a protein:
Function:
Involved in the transport of four structurally unrelated drugs, including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Miscellaneous:
MISCELLANEOUS: Overexpression reduces the sporulation efficiency possibly by modulating the function of KinA.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFSVLKKLGWFFKAYWLRYTIAIVLLLAVNVIEMFPPKLLGNAIDDMKAGAFTAEGLLFYIGIFFVLTAAVYIMSYFWMHQLFGGANLMEKILRTKLMGHLLTMSPPFYEKNRTGDLMARGTNDLQAVSLTTGFGILTLVDSTMFMMTIFLTMGFLISWKLTFAAIIPLPVMAIAISLYGSKIHERFTEAQNAFGALNDRVLESVSGVRVIRAYVQETNDVRRFNEMTADVYQKNMKVAFIDSLFEPTVKLLVGASYLIGLGYGAFLVFRNELTLGELVSFNVYLGMMIWPMFAIGELINVMQRGNASLDRVNETLSYETDVTDPKQPADLKEPGDIVFSHVSFTYPSSTSDNLQDISFTVRKGQTVGIAGKTGSGKTTIIKQLLRQYPPGEGSITFSGVPIQQIPLDRLRGWIGYVPQDHLLFSRTVKENILYGKQDATDKEVQQAIAEAHFEKDLHMLPSGLETMVGEKGVALSGGQKQRISIARALMANPEILILDDSLSAVDAKTEAAIIKNIRENRKGKTTFILTHRLSAVEHADLILVMDGGVIAERGTHQELLANNGWYREQYERQQLFTAEEGGAGA
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MRHKMNKARKLDNEDILDHAMKIIHLLTGQHYIVVKKHKDYITVSRTENLVVDPVPYSDIHENNKDKNLCYGKMLELANMIIQLLAEEFSCSSDFHEDGQEERNKHLHKDQNQFSEHLANLVILVNKMTKDKSQTTGKIFNYTLEIIYLLIGEDYVVVKKENDNDSQSSRCLSEYTCGDQTIITDDPLISLTQEKNSDKKIMDLAKKISQVLMKKAPAKCEEDALYSCMEQYLGAYREVYKVDMESEHTINTLAEAGTNLNKTTQDHTRLDSINEVTIRDEMDSAAHLSKQNRKNKRKSKPVRIVAQDLILHKEKNTFAVQTPTKAHDLSVTEKECAEDETERSLLFPETVNTICSSTVMDEPLEKEEVMGCEDQEKYLSQTHFMNFQTLGLQSRRYMCTLCGKCFTKSSHLSTHQRVHTGAKPYLCVDCGKRFTSSSTLVDHQRIHRGEKPFACSDCGKCFTKNSNLIDHLRTHTGEKPFECLQCGKRFARSSNLAEHHKIHTGEKSFICSVCGKGFSRSSSLAEHYRIHTGGESYICSECGQCFTKNSSLVRHQSIHTGKKPFVCSECGKGFSNSSNLARHHITHTGERPYMCPICGRSFNQNSNLVSHQKTHKSETFE
The following text describes a protein:
Function:
Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.
Subcellular Localization:
Nucleus.
Sequence:
MYRALIDSQMSMAATAAVSPSDYLQPAAAATQDSQPSPLALLAATCSKIGPPAVEAAVTPPAPPQPTPRKLVPIKPAPLPLSPCKNSFSILSSKGNILQIQGSQLSASYPGGQFVFAIQNPTLINKGSRSNASIQYQVPQIQGNSSQTIQVQPNLTNQIQIIPGTNQAIITPSTSGHKPVPIKPAPVQKSNTTTTPVQSGANVVKLTGGGGNMTLTLPLNNLVNTSDIGAPAQLLTESPPTPLSKTNKKARKKSLPVSQPSVAVAEQVETVLIETTAENIIQAGNNLLIVQSPGGGQPAVVQQVQVVPPKAEQQQVVQIPQQALRVVQAASATLPTVPQKPSQNFQIQTTEPTPTQVYIRTPSGEVQTVLVQDSPPATAATTSTVSCSSPALRAPHLSGSSKKHSAAILRKERPLPKIAPAGSIISLNAAQLAAAAQAMQTININGVQVQGVPVTITNTGGQQQLTVQNVSGNNLTISGLSPTQIQLQMEQALAGEAQPGEKRRRMACTCPNCKDGEKRSGEQGKKKHVCHIPDCGKTFRKTSLLRAHVRLHTGERPFVCNWFFCGKRFTRSDELQRHARTHTGDKRFECAQCQKRFMRSDHLTKHYKTHLGTKGL
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MAQRMARGRAWAPPASCKPEAVSFADVAVYFSPEEWRCLRPAQRALYREVMRETYGLLASLGLGGAKPALICWVEEESEVWGPCAQDPEVAMCRTEVHSDCRHEKERKRPREETEAMQKTFSPEPGQKEPQLSFAGSASGIQATVLRADKRHGCHLCGKSFAQRPTLVEHLYTHTGEKPFQCPDCNKCFGRASSLTMHRAIHRGERPHQCPDCGKSFTQRSTLVAHMYTHTGEKPFCCPDCNKSFSRSSSLSSHRAIHRGERPHCCPDCGRAFTRRSGLIAHLRIHTGEKPYCCADCGRCFSQRSAFREHQRVVHSGVTPFTCTHCGRAFADSKYLRRHMRIHTGEKPYSCPDCGRCFRQSSEIPAHRRTHTGERPYPCPQCGRQFRTKSAMTSHQWVHRPGAKGHKDKKARQLSISLDPRQEDPDPPVGF
The following text describes a protein:
Function:
Regulates organ size by inhibiting apoptosis and promoting cell proliferation by influencing the expression of G1/S-specific cyclin-E (CycE) and apoptosis 1 inhibitor (th). Negatively regulates the Hippo signaling pathway.
Subcellular Localization:
Cell junction, adherens junction.
Sequence:
MTTQRTQTQARNPGNSDSDYETLMQRLHIGGGGGAGVGGGGGSGGPGDGGVAMRSYQRSPGAIENYLQESQQQQQQHQMQQMQQLHHNQDYKLYERGNIIAASKYATPRPVEQIQHTHNGSAQIYAPTAQILGQRIAPQKHSPVYENLEFYGQFDSNHKRAQPQSPGSRQSAILNGYLLMQPIRAGRFAHTPVPENQGSASLGTTRAAGGPPPPSGRSAALGPTGDLEEHAAPIYENIIPHSGQRAQPQASPATATMYQEMQPTSNSSGSSSTAGLDLNALLASPMHQRSISSNTASSSSLGSPTQRYRNLSLPSHLSPVPTAQSVAKLQQHTPVKSPGGAINVSVNPNYIEDINSSDYVCMTANLHRNTAAGLATGRAAATGAPAQRTVQEPPIITSSLAMGMATAAPPTTSNAPTSAAAAPAAPTSTASLRATPIAMTAPLAVATSPTPSQGSTAVNAALKPRRGLTKNLLPYSVTPPRPAGPTEAQRKIEELTRQLEEEIEQSEEHGEYFGICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPLDGRLLCRGCHLQRLALQSSPHARHQEPVCASYQYMG
The following text describes a protein:
Function:
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
Subcellular Localization:
Cell outer membrane.
Sequence:
MAVKSLVFRRKFPLLVTGSLLALQPVAALTVQAADQFDCKVSATGGWDCSPLQNANANLPPRPAHTATSVSTAAAGSSVSGSGGETVEAEPTQRLVTESGGRALKSRSADYSHLDWIPREKLTAAQLAEIGPYCGGSYIEPVRPGMDDGAPSDESPTYVSAKASRYEQEKQIATLAGDVVLRQGSMQVEGDEANLHQLENRGELVGNVKLRDKGMLVVGDHAQVQLDNGEAQVDNAEYVIHKAHARGSALYAKRSENAIIMLKDGTYTRCEPSSNAWTLKGNNVKLNPATGFGTATNATLRVKDFPVFYTPYIYFPIDDRRQSGFLPPSFSSTSDTGFTLVTPYYFNLAPNYDATLYPRYMAKRGMMLEGEFRYLTHSSEGIVNAAYLNDKDDHREGFPDYSKDRWLYGLKNTTGLDSRWLAEVDYTRISDPYYFQDLDTDLGVGSTTYVNQRGTLTYRGDTFTGRLNAQAYQLATTTDVTPYDRLPQITFDGFLPYNPGGMQFTYGTEFVRFDRDLDENIYFNDDGSIRGKRPDASLQGLARATGDRMHLEPGMSLPMTRSWGYVTPTLKYLYTKYDLDLDSQGKTDLNKRDESFDSNQDRSLPLVKVDSGLYFDRDTTFAGTPFRQTLEPRAMYLYVPYKDQDSLPVFDTSEPSFSYDSLWRENRFTGKDRIGDANQLSLGVTSRFIEENGFERASISAGQIYYFRDRRVQLPGLTEKDLKRLNLDPSGLDNDSWRSPYAFAGQYRFNRDWRINSDFNWNPNTSRTESGSAIFHYQPEVDPGKVVNVGYRYRADARRFDSSRGTFRYGNENDIIKQHDFSVIWPLVPQWSVLARWQYDYNKNRTLEAFGGFEYDSCCWKLRLINRYWLDVDDDAFLVQSEKADRGIFLQIVLKGLGGIVGNKTEMFLDKGIQGYRQREDQAM
The following text describes a protein:
Function:
Probable subunit of an amino acid transporter involved in the regulation of the amino acid metabolism. Stimulates amino acid export by activating nonselective amino acid facilitators.
Miscellaneous:
MISCELLANEOUS: Overexpression of GLUTAMINE DUMPER 6 leads to free amino acid levels accumulation and plant size decrease.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The VIMAG motif is necessary for the function of the protein.
Sequence:
MRPTPKVEIWKSPVPYLFGGLFLLVLLIALALLSLVCTHQKPSSSSNNNHMDEEDDVGDKDAKPITREYLPKIVVILAGDNKPTCLAVPVVVPPPTSIFRCNCDNVTVIST
The following text describes a protein:
Function:
Mast cell degranulating peptide. Causes histamine release from rat peritoneal mast cells in vitro. Has antibacterial activity against the Gram-negative bacterium E.coli K12 and Gram-positive bacterium M.luteus NCT C2665.
Subcellular Localization:
Secreted.
Sequence:
FLPLVRGAAKLIPSVVCAISKRC
The following text describes a protein:
Function:
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
Sequence:
MSSATKKMITLKSYDSKTFEVSEAVAHESHTIKHMIEENCAENVITIPNVNSKILAKVIEYCKKHVEAAAKASSDDLNCWDADFVKVDKAMLLESASSNDLEVQKNVEAGWDAAVSLDDLKAWDAEFMKHVDQAMLFELIQAANYLNIKSLLKLTCGGHDQGEDAGGDSQDV
The following text describes a protein:
Function:
May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin.
Subcellular Localization:
Secreted.
Sequence:
MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKYWKERHLKQIQIGLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYSDCAWEIVRVEIRRCLYYFYKFTALFRRK
The following text describes a protein:
Function:
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells (By similarity).
Miscellaneous:
MISCELLANEOUS: [Isoform Short]: Lacks the kinase domain.
Subcellular Localization:
Nucleus.
Sequence:
MRHSKRTYCPDWDERDWDYGTWRSSSSHKRKKRSHSSAREQKRCRYDHSKTTDSYYLESRSINEKAYHSRRYVDEYRNDYMGYEPGHPYGEPGSRYQMHSSKSSGRSGRSSYKSKHRSRHHTSQHHSHGKSHRRKRSRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKVGGRRVAVKIVKNVDRYCEAAQSEIQVLEHLNTTDPHSTFRCVQMLEWFEHRGHICIVFELLGLSTYDFIKENSFLPFRMDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVKSDYTEAYNPKMKRDERTIVNPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSREHLAMMERILGPLPKHMIQKTRKRRYFHHDRLDWDEHSSAGRYVSRRCKPLKEFMLSQDAEHELLFDLIGKMLEYDPAKRITLKEALKHPFFYPLKKHT
The following text describes a protein:
Function:
Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P), 2'-AMP, pNPP, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate. Cannot hydrolyze glucose-6-phosphate, fructose-6-phosphate, NAD(+) or 5'-AMP. May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.
Sequence:
MKWDEIGKNIAKEIEKEILPYFGRKDKSYVVGTSPSGDETEIFDKISEDIALKYLKSLNVNIVSEELGVIDNSSEWTVVIDPIDGSFNFINGIPFFAFCFGVFKNNEPYYGLTYEFLTKSFYEAYKGKGAYLNGRKIKVKDFNPNNIVISYYPSKKIDLEKLRNKVKRVRIFGAFGLEMCYVAKGTLDAVFDVRPKVRAVDIASSYIICKEAGALITDENGDELKFDLNATDRLNIIVANSKEMLDIILDLL
The following text describes a protein:
Function:
Actin-myosin network stability during cellularization. Might be involved in increasing actin-actin interactions or membrane-to-cytoskeleton attachments. nullo together with Sry-a and bnk may provide auxiliary functions, by acting both to stabilize a large and dynamic microfilament structure and regulate its functions.
Sequence:
MGSTHSAEKVKSVEDSTSPANPGIFCTPLPGFISNIQRLVLRKLSISARKQKRLNKRSKHLLRPMPRCSSFGSCGTLLTPTKKSASNIADRRYAQWKCSFEHLAQKQPRLHDISEAMTGQTTPRGFPSHTDPKRCLMVMDSSSPESPLYDMVGGQKVRRRLSLRSHALVRRPSARQKAEQAKLDAQFQRDLRDLEDYYGGFHFAQRRERLVKV
The following text describes a protein:
Function:
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).
Sequence:
MGRVLRAIRPLVSHLLNKKACVIGGTLATLVSDYRTQVDFVAVYLAEAHAEGAWEMGHNISYIKDHTSLQERIEAAKDLLKVDATSHNCLTDDVTDTSKFRLVVDKMDSLFTRMFRVHPDRVIFIRDGKMVYIGNSILGQIQNPTYLMTHEARDWLEANVGSAAAANQ
The following text describes a protein:
Function:
Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGAQAPSAAVERTAIKKVSVRLVPFVALMFFVNYLDRTAVSFAEPNGMGQDLALTAAQFGFASGIFFLGYIVLEVPSNMALHRFGARRWLARIMVTWGIVSLLFTWVSSSGQLYTLRFLLGVAEAGFFPGAILFLSQWVPSRHRTKILGLFYLAQPLTTVFGAPLAGWLIGRHGLFGLEGWRVMFLFVSLPAIVLGVVAWFYLIDKPADAKWLTPAERDWLTTELAAENAQKTGHEGKHAKGDLRKAFGSGRVWTLAAVYFGFVYGLYALAFFLPTIINGFQDQYDTTFSVMDKAWITAIPYLPAAIVLFFWTRHATRHGTRTWHVAGPAVVGGVSIPLALYMGSPTATVAVITVTACAIFAALPVFWSVPSRFLTGAAAAAGIALINTAGNVAGFASSYITGWLKDWSGAYYVPLYLVGFFMLLSAALMILLAARNGTGEPATAPEPQAEEALR
The following text describes a protein:
Function:
Primarily acts as an independent SigF regulator that is sensitive to the osmosensory signal, mediating the cross talk of PknD with the SigF regulon. Possesses both phosphatase and kinase activities. The kinase domain functions as a classic anti-sigma factor-like kinase to phosphorylate the anti-anti-sigma factor domain at the canonical regulatory site, and the phosphatase domain antagonizes this activity.
Sequence:
MDSAMAAVVRASGAFGGILYALPPGEDAVWQVLVTGVPQEMAAPWRRVGLKDPMPVADAVREHRLVWAGGREEMAREYPRLALVLPYDFGLAAAPVVSGTALRGGLVLLWPGNHPARLSAGEQDVIRAGCRRLGDSLQRAIDRGEPLRPPERPRTLPPAAPRTPSPAEATALSAFVDRLPGGSCALDLEGHLTLVTPGAAELLGVDRSLLVGALPWEALPWMDVPHVEDRYRAALVSRRPQGFTVLRPPKTWLSFELYPDATGLSVRITPGSPDADSPPSRSVQASGPSRATVLYHLMHLASTLTEAVSVQDVVEQTADQLMPALGAQAMVVMAPADGRLKIVGQRGYRPELLRRFDGAPLTAAIPGADVMATGVPGFWTTFEELRGAYPAMTHEDGMAAWALLPLIASGRPIGSLLLSYRRPHVFPPGERAALTSLAGLVGQALDRARLYDAKHHLAHRLQSALLPHTLPDVPGLNVAARYLPAARGLGIGGDFYDVIRLDEHTASVTIGDVQGHNVDAAALMGQVRTAVHAHATVGAPPGDVLARTNRLLTDLDPGLFTSCAYVHLDLATHRACVALAGHPPPLVRHSDGRVETLRVPPGLLLGIEPDTVYPSLEFPLPPGSVLVLYTDGLVEAPGVDLDDAIAALGGLVEHGDPGDLDAMADTLIRHAPTPGDDIALVLVGPRASAPGHSRGRSIVFRDKKDERRSTRAGSGGEDP
The following text describes a protein:
Function:
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MNGSMYGYGGNGMNQQNMMGSYGMPSTNPASYTGTPGMGYQDPMTGMYGQVPQQQQQQQYQQMPATGAPTYTDASYGMMANNDPFSYSNPGSVMSYDPMNPYGNVGMPVQPSQQQTYGGYDPMQAAGAYGMPGMVQQQPMQPDTSSYMQTQQTGFQQIQPQQTQNAVANPFMSYQQTGMQQNILPQRTGTQYSQMTGGAGVLGGYNPFQSATGGIVSQPTGMAPLKAQKTGQIHSSHAMDTRLSFVSAADQMKFEQLFKSAVNTEESMSGETARAILSRSRLPNDVLANIWRLSDTTRSGRLLFPQFVLAMYLCNLALTRKPLPDPVPEPILNEVNSMVDAISFSLGDGSNQYSLPFTGSASMPNNGAQPMLPQRTGMQPQPAGMPPMLPQRTGMQPMMPQQTGMQPMIAQRTGMQPVMPQQTGVQPMVAQRTGMQPMMPQQTGVQPMMPQRTGMQPMMPQRTGMQPMMPQQTGVQPMVAQRTGMQPMMPQRTGMQPQPVGMPPMLPQRTGMQPMMPQQTGVQPMVAQRTGMQPMMPQRTGMQPMMPQRTGMQPQPAGMPPMLPQRTGMQPMMPQQTGVQPMVAQRTGMQPMMPQRTGMQPQPAGMPPMLPQRTGMQPMMPQQTGVQPMVAQRTGMQPMMPQRTGMQPMMPQRTGMQPMMPQQTGMAPLVAMPTGKPGEWGFVNAPSADLPAINALGQQLMPNAPMNQHLQNFQTNSDIPWAISKHEKKVYDQIFDAWDKDHKGRVSGNAALEIFGQSRLQREELERIWALADNGDKGHLDRDEFAVALHLIYRKLNGYDIPATLPPELIPPSTRNFSDSLNRVKQFIKEDTSRKGAFDISNQSRLRQNSFYQSNDEAPAKDPTLYRFNEDETVGYVSSARRKSGAEASNKPDTVDAEIEAMKEAVRQKKILLEALEVKKLEQGADEKSVTLLRSSIADLKSKLDKLDKSGDRHTAASLQQKYEDLVKRIDELRKSVRNANDNLVDAAVNVVKDAFTREASEKISDVDPRILDASKALKRRILELTGVPIPSSLGEVTSASTVKRCMDSLDDAVTKQERNREAVSGLESNISSLQNEIRELLNKPVMSTAPVTHVKEEAPVFSARNTQSAQVNSTTPTPTPAPAPAPVKEEKHAETVEERSARIKAEAQRRMNERLAALGIKPRRGSAASQTLSPANSSTSLSSSFSRMSVNDKTEERTQSLQKESFASKQPTANQPVMAKQAAPAEQPVPQMQAVAPRAAEPMQPAKLTVPLSSIQRENKLEQNETARAPVYSPAMNAPSIGGIVGNASSDAHLSRSLQPSLGTSAAPRDNVSNVPTASTPSSSAPSGSFSANASNFRREEAPNGVSMTPVPSQFSHQVTPVVQSQKASPQQQSVSQPVVSHPPPSAPPAAPVPLNSVPRSVMPPASGSSQSTIPPSSHSTPSSEGAPAAPPPPPVPSMAPPSLPKVAASNVSQSNSQTMSQPASVPLSVNGPLKSNPFSKNTGPGAPLAPRAMHTYQYTDNDNWSQKSDEEEESDDEVTSRKDAAALASRLFGGMAPIRPMSASVTGGTMSKPPTPQSHPPPPPSMAAPPVPPAAPPAAPVPPPAPSASARNVSPAVDPNTRSALLQQIHTGARLRKTVTNDKSKPIGGRVVGDTADSNAWYGNLS
The following text describes a protein:
Function:
May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells (By similarity).
Subcellular Localization:
Cytoplasm, perinuclear region.
Sequence:
MAADPSPPSAMAQPRPLNLNNEVVKMRKEVKRIRVLVIRKLVRSVSRLKSKKGSEDALLKNQRRAQRLLQEIHAMKELKPDVITKSALNDDINFEKTCKKPDSTATERAIARLAVHPLLKRKVDALKAAIQAFKDARQNAPEAESSKSASKESQCEDIPRSQAEASESQHPERTVVGEQKGKDKDPTTAKKAGSGSKEKLAKGKQGPKAVATPHSPGKPSEKGAGINSERQGAPTPGNHSQGKASTRTTEDSVCEPDDNSISKEEVSEEEKEYFDDSTEERFYKQSSASEDSDSGDDFFIGKVRRTRKKECAVPSSAKEQKPLPKVSSKTNTLETHWDIRNDKHKLIPEARKLESVFFHSLSGPKSSRRDPREQAPKNKAPDIPENEPPIQNKFTKSARRGFESAKQPSYAPLHPSWEASRRRKEQQSKIAVFQGKKITFDD
The following text describes a protein:
Function:
May be involved in ion homeostasis together with BTN1 or BTN2.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Correct localization requires BTN2. Localizes to the mother cell in small budded cells and to the bud in medium and large budded cells. Transported to the bud tip by an actomyosin based process. Compartmentalization maintained by a septin mediated membrane diffusion barrier at the mother-bud neck.
Sequence:
MSQTITSLDPNCVIVFNKTSSANEKSLNVEFKRLNIHSIIEPGHDLQTSYAFIRIHQDNAKPLFSFLQNLDFIESIIPYHDTELSDDLHKLISISKSKILEAPKQYELYNLSNLTNNPKQSLYFAFLQNYIKWLIPFSFFGLSIRFLSNFTYEFNSTYSLFAILWTLSFTAFWLYKYEPFWSDRLSKYSSFSTIEFLQDKQKAQKKASSVIMLKKCCFIPVALLFGAILLSFQLYCFALEIFIKQIYNGPMISILSFLPTILICTFTPVLTVIYNKYFVEPMTKWENHSSVVNAKKSKEAKNFVIIFLSSYVPLLITLFLYLPMGHLLTAEIRTKVFNAFSILARLPTHDSDFIIDTKRYEDQFFYFIVINQLIQFSMENFVPSLVSIAQQKINGPNPNFVKAESEIGKAQLSSSDMKIWSKVKSYQTDPWGATFDLDANFKKLLLQFGYLVMFSTIWPLAPFICLIVNLIVYQVDLRKAVLYSKPEYFPFPIYDKPSSVSNTQKLTVGLWNSVLVMFSILGCVITATLTYMYQSCNIPGVGAHTSIHTNKAWYLANPINHSWINIVLYAVFIEHVSVAIFFLFSSILKSSHDDVANGIVPKHVVNVQNPPKQEVFEKIPSPEFNSNNEKELVQRKGSANEKLHQELGEKQPASSANGYEAHAATHANNDPSSLSSASSPSLSSSSSSSKTGVVKAVDNDTAGSAGKKPLATESTEKRNSLVKVPTVGSYGVAGATLPETIPTSKNYYLRFDEDGKSIRDAKSSAESSNATNNNTLGTESKLLPDGDAVDALSRKIDQIPKIAVTGGENNENTQAKDDAATKTPLIKDANIKPVVNAAVNDNQSKVSVATEQTKKTEVSTKNGPSRSISTKETKDSARPSNNNTTTTTTTDATQPHHHHHHHRHRDAGVKNVTNNSKTTESSSSSSAAKEKPKHKKGLLHKLKKKL
The following text describes a protein:
Function:
Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). Cooperates with kif8 and dynein to organize interphase microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MNNNNNNNNNKTTMNSMIVTVRIRPESQSEILNKNCKTIVRVIDDNMLVFDPNDIDIGAFNNNRNNKQSQQPVEQKYIFDRVFDQYATQEEVFENTTKELVSYVISGHNASVFAYGASGAGKTHTMVGGINTGPGIMVLTMKELFSLIEKDRSNQYIVSMSYLEVYNETIRDLLITNTGGGGNSNNKVLELCEDENKQIVIRDLSWEYPTSADQVFKLLKYGNLNRKQSPTQTNQTSSRSHAVLQITVKQQNLQDKSKISFGKLSLIDLAGSERASKTLNTGDRLKEGTSINKSLLALGNCIKALGELCKNQQSQQQSSNPNFIPYRDSKLTRILKDSLTGSCKTIMIANISPNSSSFEETHNTLKYAQRAKSIKTQITKNVFASSTNLITQYNEIIKEQREEIKQLKLKLIQATSNNNNSNNNNNNNNNNYFSNSFGSCGNKNQPIKQPTPPTSLFHQQNQKYYRNDDDDDDDNDQEENNDEVLINEDDEEVDGEDSNNRDNDESMIQQLEEMSLLINSNLQDTLTLKKTQSIQRQRKRELENELKSLEKQQQSILNENNNVDIIKRTNEIGSQILKIKTLESSINEKLEMNNQWRRKLQSELTLKFVNSPKNLKILIQQARAATLELDRFDLTERMIDDRSKLNLKTNECKSLKDSLSWMFGILSDGFKLLTENNLATDDFLKDFLKSGDLINNLDNSFIINENNDSNNNNIIENDDIDLSFNNDINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNVPLNCNNSNSNINNKNQNIINPSPLKPRRIMSGSNNIIKSTNSNSRMTSTATTTAASTATATTTTIGKEKKGEIRSIVNPINKISSSTSLLPSSSTKISNTTPLYSRTSILRKRTLEIDDSTDSNPRTKKINVSSPVVTKPKQLLPSTTTATTTTLSSPLVNKPKQILPTTSSLQPKPHTKIQPHKNNNNNNNNIAPQMNMNIQIPNPIPIPIPMHVQIPISNPIPMPSPSSMNLKEKLDSLSQLCNNRSAKNENYNHNNSFNSQNPFVHPLQMHPPQLQLPLHPPQTMIMQSNMDLKMKLDSLSFFNNNNNNHQAQNDLSFDYGQNTLSNENLILHNKIASLSSTLINQPHPMRVKKLTPTSTISSSISTRPITTSTTTSTTVPSVVSNRIKSLVHSNSPIKENLYKEKLSSTASATLTPNRNNSQIVQPFKRGVLGNGPTSSSSRLLPSSRTTVNTSRKIIK
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane. Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MKLRYLIPKDIYLIAFPAFGFAFGWYLDRKETERLTLFRDKSALYGRVLKEGEAPSWP