lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a role in tight junctions and adherens junctions. Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity.
Subcellular Localization:
Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus.
Sequence:
MEEVIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKIAAIVVKRPRKVQVAPLQGSPPLSHDDRGFEMMDEFDGRSFRSGYSERSRHSSHDMLSHSWEDSRERGRPHQRAQSRERERSRGRSLERGLDHEDYGRSHERSRGRSLERGLDRDFVSRDYSRGRSIDRDYDRDYERSYHQAYEPDYEGRYSPSYDRRAHPETRYERSRSREHLRSRSPTPESRSRQEHKGQHDPDRPIGVLLTKSKANEEYGLRLGSQIFIKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSKQTLINIPSLNDSDSEVEDISEIESNRSFSPEERRQQYSDQEYHSSTEKLKERPSSREETSGRMSRMGATPTPFKSTGDITAAGVTEANKEPRSQEESPVPQPRTASRVFLRPSPEDEAIYGPNTKMVKFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGETVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETPQSLAFTRGEVFRVVDTLYDGKLGHWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRENAGDRADFWRMRGQRSGVKKNIRKSREDLAAAVSVSTKFPAYEKVLLREAGFKRPVVLFGPIADIAMERLTTELPDLFQTAKTEPKDAGSEKSSGVVRLNTVRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGIKTIRQRLNPTSNKSSRKLFDQANKLKKTCSHLFTATINVNSANDGWFGSLKDSIQQQQNEAVWVSEGKMEGMDDDAEDRMSYLTAMGADYLSCDSRLISDFEDTDGEGGAYTDNELDEPAEEPLVSSITRSSEPVQHEEVRNQNREDSFNYSKSNLSAMAGSEIPGGSTKGCPPPIAVKPAFGRSILKPSTPVPMPESEEVGESTEEQEEAPKSVLGRVKIFEKMDHKAKLQRMQELQEAQNARIEIAQKHPDIYAVPIKAPKPDAGLPQHMSSRPPEPQKAPSRLYQDTRGSYGSDPEEEEEYRQQLAAHSKRGYYSQPSRYRDTEL
The following text describes a protein:
Function:
Involved in gene regulation and confers tolerance to drought and osmotic stress.
Sequence:
MERYEIVKDIGSGNFGVAKLVRDKFSKELFAVKFIERGQKIDEHVQREIMNHRSLIHPNIIRFKEVLLTATHLALVMEYAAGGELFGRICSAGRFSEDEARFFFQQLISGVNYCHSLQICHRDLKLENTLLDGSEAPRVKICDFGYSKSGVLHSQPKTTVGTPAYIAPEVLSTKEYDGKIADVWSCGVTLYVMLVGAYPFEDPSDPKDFRKTIGRILKAQYAIPDYVRVSDECRHLLSRIFVANPEKRITIEEIKNHSWFLKNLPVEMYEGSLMMNGPSTQTVEEIVWIIEEARKPITVATGLAGAGGSGGSSNGAIGSSSMDLDDLDTDFDDIDTADLLSPL
The following text describes a protein:
Function:
Ergosteryl beta-glucosidase involved in the ergosteryl beta-glucoside (EG) catabolic pathway and vacuole formation via hydrolysis of EG to generate glucose. Is also able to hydrolyze cholesteryl beta-glucoside and sitosteryl beta-glucoside to generate glucose; and C6-7-nitro-2,1,3-benzoxadiazole (NBD)-GlcCer to generate C6-NBD-ceramide (Cer).
Miscellaneous:
MISCELLANEOUS: Present with 1070 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytosol. Vacuole membrane; Peripheral membrane protein. Note=Localizes in the cytosol until the initial logarithmic phase, then targets to a yet unidentified organelle with a granule structure in the middle logarithmic phase, and finally localizes at the vacuole membranes in the stationary phase.
Sequence:
MPAKIHISADGQFCDKDGNEIQLRGVNLDPSVKIPAKPFLSTHAPIENDTFFEDADKVSFINHPLVLDDIEQHIIRLKSLGYNTIRLPFTWESLEHAGPGQYDFDYMDYIVEVLTRINSVQQGMYIYLDPHQDVWSRFSGGSGAPLWTLYCAGFQPANFLATDAAILHNYYIDPKTGREVGKDEESYPKMVWPTNYFKLACQTMFTLFFGGKQYAPKCTINGENIQDYLQGRFNDAIMTLCARIKEKAPELFESNCIIGLESMNEPNCGYIGETNLDVIPKERNLKLGKTPTAFQSFMLGEGIECTIDQYKRTFFGFSKGKPCTINPKGKKAWLSAEERDAIDAKYNWERNPEWKPDTCIWKLHGVWEIQNGKRPVLLKPNYFSQPDATVFINNHFVDYYTGIYNKFREFDQELFIIIQPPVMKPPPNLQNSKILDNRTICACHFYDGMTLMYKTWNKRIGIDTYGLVNKKYSNPAFAVVLGENNIRKCIRKQLSEMQKDAKSMLGKKVPVFFTEIGIPFDMDDKKAYITNDYSSQTAALDALGFALEGSNLSYTLWCYCSINSHIWGDNWNNEDFSIWSPDDKPLYHDTRAKTPTPEPSPASTVASVSTSTSKSGSSQPPSFIKPDNHLDLDSPSCTLKSDLSGFRALDAIMRPFPIQIHGRFEFAEFNLCNKSYLLKLVGKTTPEQITVPTYIFIPRHHFTPSRLSIRSSSGHYTYNTDYQVLEWFHEPGHQFIEICAKSKSRPNTPGSDTSNDLPAECVIS
The following text describes a protein:
Function:
Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly; Required for assembly of cytochrome c oxidase (complex IV).
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MYKRYRKERRRRRTSLNEHGKRMEAKTRDACSAEPKSLTPLQKQMLKRQQELEYWKLHSKQVRRCNLITGLTIGAFVVGLFSYTILSVKQEKIIDEIDEEAKTFIMKGPRTGANS
The following text describes a protein:
Function:
Binds to 23S rRNA.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MKKIEDNNTLVFIVDLKADKKIKAAVKKMYDIQAKKVNTLIRPDGKKKAYVKLLM
The following text describes a protein:
Function:
Might be involved in phosphate export. Overproduction of YjbB reduces the elevated levels of polyphosphate (polyP) in a phoU mutant that accumulates 1000-fold higher levels of polyP than the wild type, suggesting that YjbB exports excess intracellular phosphate (Pi) in the phoU mutant and thus reduces the levels of polyP.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKKPLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALAPALVIVLGADVGTALMARILTFDLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGVQVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANLGSGLLAMLNNSAANAAARRVALGSLLFKLVGSLIILPFVHLLAETMGKLSLPKAELVIYFHVFYNLVRCLVMLPFVDPMARFCKTIIRDEPELDTQLRPKHLDVSALDTPTLALANAARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEELAEEESRRWAEIIEMSLNLEQASDIVERMGSEIADKSLAARRAFSLDGLKELDALYEQLLSNLKLAMSVFFSGDVTSARRLRRSKHRFRILNRRYSHAHVDRLHQQNVQSIETSSLHLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY
The following text describes a protein:
Function:
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MKSYKVVIVGDKAVGKTVYIDSFITGEFMKSYIQTIGVTVKDIDFHTSIGKVGFQCWDISGDPKMVGIVDGFLIGADCAIIMFDVTDRQTYRSVAGWYDTLSRVVPGIPVVLCGSKTEDPNRKVGPSSIIFHRKRGLSYYDISTQSNFNKEKPFIYLLNVLNKRKDIALATPPYESEAINEQKDNSKIDLSKVDNCDNFNENPNHNNNTNLPLVIPITFFDPEDLNSDFKKNLNLN
The following text describes a protein:
Function:
May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
Subcellular Localization:
Microsome membrane.
Sequence:
MKRAGTLRLLSDLSNFSGAARLRELLAGDPAIRVRCSLDGRHLLLLRPPGAPAPQLLVAVRGPGAELERAWPAGHSSPLDAFFLPWPARPALVLVWESGLVEVWGAGVGPGWRLLQSTELCRGGGARVVAVAAPRGRLVWCEERQADAEDRLRSPAAAFSHCVCVRTLEPSGEAGTNLGRTHILLHHCPSFGLVASRKDLFLVPTATTWPGVGHILLIWSPGKGKVIVVAPSLGLSHSKSLNPGRGDTWDFQTLIRGLPGLLTPRQPLTVHTWAPTPQGLLLLDFRGTVSLVQSHGGTRAVGTLQEAPVSLAGSAALGTFHGTLACVLGSTLELLDMGSGQLLERKVLSTDRIHLLEPPAPGMENEEELETRGGLRLLSALGLFRVGWEAPQGLELPSAEDLVFEEACEYYQRRSLRGAQLTPEELRHSSTFRAPQALASILQGHVSPSTLLTTLRAELRDYRALEQLKAQLVAGDDEEAGWTELAEHEVARLLRTELMGDQLAQLNTIFQALPTAAWGAILRVLQLQPDGNGKLRSQAPPDVWKKVLGGTAAGKEPSNGILPLFELLCQCLCRLEPRWLPPFVELAQQQGGPGWGAGGPGLPLYRRALAVLGEEGTRPEALELELLLGSGRPKAVLQAVGQLVQKEQWERALEAGLALGPSSPLLRSEIFKLLLAEFARHRRLDAHLPLLCRLCPPDLAPAELLLLLRTHLPDELEPPTPFPEPRAEPPLTVGLLRALLEQTGTQGRPSGPVLSLYEDILWDPGTPPPAPPRGPMTALQASDHPGLEAWAPSGQGLCVTDRG
The following text describes a protein:
Function:
A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its oxygenated derivatives. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Participates in the conversion of arachidonic acid to omega-hydroxyeicosatetraenoic acid (20-HETE), a signaling molecule acting both as vasoconstrictive and natriuretic with overall effect on arterial blood pressure. May play a role in the oxidative inactivation of eicosanoids, including both pro-inflammatory and anti-inflammatory mediators such as leukotriene B4 (LTB4), lipoxin A4 (LXA4), and several HETEs.
Miscellaneous:
MISCELLANEOUS: Highly expressed in aflatoxin B1-induced hepatic tumors.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Peripheral membrane protein.
Sequence:
MSQLSLSWLGLGPEVAFPWQTLLLFGASWILAQILTQIYAAYRNFRRLRGFPQPPKRNWLMGHVGMVTPTEQGLKELTRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYTILKPWLGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWKRLISEGSSRLDMFEHVSLMTLDSLQKCVFSFDSNCQEKSSEYIAAILELSALVAKRHQQPLLFMDLLYNLTPDGMRFHKACNLVHEFTDAVIRERRRTLPDQGLDEFLKSKAKSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLANDPEYQERCRQEVQELLRDRDPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVWPDPEVYNPFRFDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELILRAEGGLWLRVEPLTAGAQ
The following text describes a protein:
Function:
Starch-debranching enzyme involved in amylopectin biosynthesis in endosperm. Functions by removing excess branches or improper branches that interfere with the formation of double helices of the cluster chains of amylopectin and crystallization of starch. Works as ISA1 homooligomer or together with ISA2 as heterooligomer. The heterooligomer ISA1 and ISA2 possesses higher affinity than the ISA1 homooligomer for various branched polyglucans in vitro, but no marked differences exist in chain preferences for debranching of amylopectin and phytoglycogen between these forms.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MASLPHCLSARPLVVAAAPGRPGPGPGPWLRGGARRRNAAFSAGNAGRRVGLRRSVASAVEVGVGEDEEEGVEEEEEEVEAVVMPERYALGGACRVLAGMPAPLGATALDGGVNFAVYSAGASAASLCLFTPDDLEADEVTEEVPLDPLFNRTGNVWHVFIEGELHNMLYGYRFDGMFAPHCGQYFDVSNVVVDPYAKAVISRGEYGVPGPGGDCWPQMAGMIPLPYSTFDWQGDLPLRYPQKDLVIYEMHLRGFTKHSSSNVEHPGTYIGAISKLDYLKELGVNCVELMPCHEFNELEYFSCSSKMNFWGYSTINFFSPMIRYSSGGIRNCGRDAINEFKTFVREAHKRGIEVIMDVVFNHTAEGNEKGPILSFRGIDNSTYYMLAPKGEFYNYSGCGNTFNCNHPVVREFIVDCLRYWVTEMHVDGFRFDLASIMTRGCSLWDPVNVYGSPVEGDMTTTGTPLATPPLIDMISNDPILGDVKLIAEAWDAGGLYQVGQFPHWKIWSEWNGKYRDIVRQFIKGTDGFAGGFAECLCGSPHLYQAGGRKPWHSINFVCAHDGFTLADLVTYNKKYNSSNGEDNRDGENHNLSWNCGEEGEFAGLSVKRLRKRQMRNFFVSLMVSQGVPMFYMGDEYGHTKGGNNNTYCHDHYVNYFRWDKKEESSDLQRFCSLMTKFRKQCESLGLADFPTAQRLHWHGHQPGKPDWSETSRFVAFSTKDETKGEIYVAFNASHLPAVVGLPERPGYRWEPLVDTGKPAPYDFLTDDLPDRAHAVHLFSHFLNSNLYPMLSYSSIILELQPDD
The following text describes a protein:
Function:
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
Subcellular Localization:
Peroxisome membrane.
Sequence:
MGDSEEHKSADTLAWEKATADNNNNTSQPQTQAQAPSTSTSSKSQPAAQTSPDAPKVSVSLEQARIFLQDAQVQKETTERKAAFLRSKGISQSDIDELLKEDWIRAQSDMREIPVTSESSSSASSKVAAAITTTTTLPKTKEQHVPIITYPEFMAETHRAPPLITMNGVLNTAYAFSGIAALVYGANKYVVEPMLNQLTEARVDFHDNVKDNLDRLVEKLEQTVSELPPGYKASDGRAGRYKDAYDDDDEDNMSTYEDPTEMFHRDVGIQTSPPPTPSVRAMSLPSRPGTAMSARSLSEIYEAHSRAQSRAASAISERHMNHTQKQQRRLAELVTSVKEINEGLTSQCEDYDELRTTVDVFHGELEQLALQHYDFTGGFSLYGYTNRSEPNDEIKKAKENIRRVKGVLLTTRTFATPAPGASGR
The following text describes a protein:
Function:
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
Subcellular Localization:
Cytoplasm.
Sequence:
MSTPRIAFIGAGNMAASLIGGLRAQGVPAAQIRASDPGAEQRAKIAGEFAIDVVESNAEAVADADVVVLSVKPQAMKAVCQALAPALKPEQLIVSIAAGIPCASLEAWLGQPRPVVRCMPNTPALLRQGASGLYANAQVSAAQCEQAGQLLSAVGIALWLDDEAQIDAVTAVSGSGPAYFFLLMQAMTDAGEKLGLSRETASRLTLQTALGAAQMALSSEVEPAELRRRVTSPNGTTEAAIKSFQANGFEALVEQALNAASQRSAELAEQLGQ
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MASSLQQQLRQIQKNNVLKSGKIRRAPSLLYDPKVAADMDLDQIFTVAVEGFHELVSVEPRLLHFEKTLLAETSIEVDRLLLSKEENDKLNKESRAILRHLAPYLPHKNTLKVLEWLVRRFSIQEYVSDEFILSFLPFHDHPFFGRVLFCAKPKSRCLQFLTHAIKARTVPSRTDIVHMMVKDKEFFALYAQTVQAAAEEACTYPILSRFWAGISLEVIACWANDNVAADTIIDRVFVSASYAACYPSSEEFRLAGFMILTGLSSCVPLASNVVQVLIEAVCEKCSSETLFSTLMFISQLVQTHTGTVVLKKEIVLKLSGLAAGKALEKISQNCCINKFLYLYWSTLIREACTPEVVEEFCSSFSLLRLTKQEAISLLQLLHAVSPNVEISECRKALEQVETKSTNVEDEVVTFEATEKDSKRERAELVKALTREIAEFSINDYKNKNVVSLADRVAIIDKRLFSKLTKKFDNELELLAQIIVSGNSDSQDLAFSRFEENIRNNENVDYQAFIPYLLFGLANPSEKVRTSCMSALSSYSVSVKHLQQVSEHEDSKQKITIYSLNDENSSVLKWLSYTELNSLLDDIIGSRKEEILVDPNYVLTYLSERLSSEKKQKDLSHKAAIVSFLSSHVIGNRFSEVRVFLLSVLDGVKEYTREIASQFLVPVLEEYVSGKRDLSTLSLDEAAGLVNLATHQDFTVLIALVSKPSNAASAACRRLVQLQSKLKNSGRLEFVRLLLNMELPPSYVSETLEAIDVPTSVFSSLLAELDLTSEVAPAASAKKVKKTAALQPKIQILTRILELLEQKDPTSHIALLSGLFEILNFVISSRDEIQFSAYLLQLLLGILYTMVSATTIEEAPPSIRIDILVNCIRSSTNPQVQNRALLLVGALASVESSAVLHGVMPIFTFMGTTLLSRDDAFSSHAIEQTVKRVVPALLSGSTDVNAAVLISCFVNAFPHIPQHRRLRLFVTLLQTMGVSKYLSSFLIQFSEKLLHIKSTHAKVIQDFCLLLVRTISLGDRFTAIEQCIGACVQLRKSELEVGEKHDKDHSEIKLEQIPFEISAASVANLRLNIIELISLICKSKQFELDLAMTLESDAKKFELLERGISDSVSLLMELDEILTTENEKEAVYAALRNIISLLPISSFAAVIKELLHDNRVLLRRSALTLLQFRVRQGTNVSVLGSLVEDVTANISENVDEETTQMAMECLSFMARRFMQQVEIFVPAVSSVIGSAGLKSSSKDVQVSAIFVPFTLEILNNAINDEEGSLVELACIHDDRLIQAALTSSRAFDSESIGEMLFETVAKYIPTRLLFKAILQVWPDCVKIGPTAAIRLFDLIGLGIDNATRSARRSLLFAEELDNVETKSVNVFLKFVMKLSDSTFRPLFFRLHSWALQDLVSTDPAGLTARQIFFYNFFTVFLKSLTSIVTNYYAYVLDDTVDLLASKETNGELRQLILSSLANAFENDSEEFWLVPARFNKIAPVLIEQISYAPLLDNSTLIKAVVELASTAASDDNFKAINTPLLQYLRSETVDVRVLAIQMETELYKRLNEDWLTTLPQSVPFIAELMEEDDDQVESATTELIKVIEDRLGDSESLQDYLT
The following text describes a protein:
Function:
Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation; its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Plays a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1. Plays an important role in the regulation of centriole duplication. Required for the onset of procentriole formation and proper mitotic progression. During procentriole formation, is essential for the correct loading of SASS6 and CPAP to the base of the procentriole to initiate procentriole assembly (By similarity). In complex with STIL acts as a modulator of PLK4-driven cytoskeletal rearrangements and directional cell motility (By similarity).
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cell cortex. Note=Localizes at the leading edge.
Sequence:
MNTRFPSSKMVPFHFPPSKLALWNPMPIGECIYLHLSYYRKPKLMVTEKAIRLAYRHAKQNKKNVPCFLLGSLTVDEDEEGVTLTIDRFDPGREIPECLERTPTASLPGDFLIPCRVHIQGLGSRDVIVHNADDFSSALKALQYHVCSKDFLDCGKLLCLRAQITPRESLDGVDFNLQWTAVTLANSFKCVPVKPIPIIPTALARNLSSNLNISQVQGTYKHGYITMDETRKLLLLLQSDPKVSSLPLVGIWLAGIIHVYSPQVWACCLRYMFSSSIQERVFSESGNFIIVLYSLTHKEPEFYECLPCESRTPDLQFQLLTNKETLHLFNNVEPSGKNPIHFELSAESQDAEAEAEVLSKISKTLPVKRSSQKLSPGKIPINKHDTDLEDEDFSPRPIPSPHPVSQKISKVQPSVPELSLVLDNNFTESSNQSNPLEMMTVENPLLIKPSQPELCDAKHSSEATTGEPFRRGPTNQLSQDTALRQSRGKQSSTCKKESLQFRNTNAKPSLSVPSPDVAEKLQAVSAGSMQKEDYPVRPSTLDSRQPSLAPQAQPHNLVFSTHNSTRPMELQVPTPSLPSYYPTNVCSCCQHHGHIQYSTINSWQGNTVGSIQDLRSESLPKHAFFHSSGCPSLCPNAIYSSSSPVSMKQGGMGAYSPHSNGEPSPVAGPSHVDSCVPHPCAMCMHTPNTAPDNGMMGLSPDAYRFVTEQDRQLRLLQAQIQRLLEAQSLDPGSHKTVATVEDTVKAAKQMELVSMEAQSSPGLHMRKSVSIAVSTGASLFWNAAGDDQEPDSQPKQDDTKISSEDMNFSVDINNEATSLPGSASSLKAVDIPSFEESNLAVEEVNQPLPESNSSSEQSKEPGVPVFFPNALLAESVSMCLQTAPTEGASNSTELPQGTKDEPYRPSDNQKIYQDLLGQVNHLLSNASQETEEPPTKAVVTNRECAKTQNTHHARKKRHNSGLVDKDCVLSATIKQLRSLGVKIDSPTKVKKNEQKVDHASVLACISPEAVISGLNYMSFGNVGMSSLSPTGVDLSMEANAIALKYLSENQLSQLSLARSKQNNGDSSVGLLHINSDRSTVGLSLVSPSNMSFATKKYMKRYGLLQSSDNSEDEEEPPSHADSESDHVLNRNPACRPVQCGHEKEPSWNACEIAQCSDCGSADTRTDVPVLRNITNQAVQPRATEHLNEDSAISLRNLKPNPAMNLRTGKAEFTHHPEKENERDIAVFPGTLPSPETLKQMNSMDSVGTFLDVKRLRQLPKLF
The following text describes a protein:
Function:
Acts as a transporter of both UDP-galactose and UDP-N-acetylglucosamine into the Golgi lumen. Apparently transports UDP-galactose and UDP-N-acetylglucosamine simultaneously, and independently, by an unknown mechanism. Functions redundantly with nucleotide sugar transporter nstp-4. May be involved in gonadal development.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MMGRNDDAFHPLLHSTPESSVKIPVPLVSVGRESSQSKGNMKTAILIWLTLQNSIHTLLIRYSRAREVDAMFVSTVAVWLTEVIKCFICLFLVAQEETPRRFIHALRTQILEQPYDTLKVCIPAMIYIVQNNLFYVAASHLDAATFMITSQLKIFTAAIFTVIILRRSLNRTQWFALAVLFVGVSLVQLQGTKAKESSGESPFVGFVAVVVACCLSGFAGIYFEKILKGSAPVSLWMRNVQMAVFSIPASFSAIYMQDSKTVNEYGLLYGFDSIVWLTVLWYGVGGLSVAVCIKYADNIAKNFATSVAIILSTIGSIFLFDFIPSFTFLLGASLVIFSIFLYSSHQSMVAALGRLRGEIPSTKEAFCL
The following text describes a protein:
Function:
Acts as a chaperone for the L4 ribosomal subunit encoded by RPL4A and PRPL4B, required for hierarchical ribosome assembly. Shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.
Miscellaneous:
MISCELLANEOUS: Present with 1630 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Distributed throughout the cell but is enriched in the nucleus.
Sequence:
MSELEATIRQAKEALAENNAKKALKILKPFKSSLKKENANNVILNEVFADAYLDNGQVEKAYPILARACELDPEGQVGGPDKFFTMGQIMGGQDGVSIITRGIMNISNTGGEMLTNVQVEKIVGGLLSVIEIWMTDLCMEPNAEEQCEELIQKAMELTEGKSPETWSTLGSIKISQQKFGEAYEAFSQAWNFFELKKQEIGSGINENGDTTQKAGLQSEYVDLLQPLLSLTKMCLEVGAYEVALKVIAAVRDIDEDNIEGYYLEGFTYYLMSKLEIFKLNNPEVSLRPENIYEFNQLIQEVPLDLSHEPISQLIYDSRLALSFALQAGVNADSKDEIVQELLGGANALLQEIGGPLDPSELTQIKKGDLVNENEDLEELDIEEEYSD
The following text describes a protein:
Function:
Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Sequence:
MAHGSPNVNCSLDEIDLNALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKFSHHRNIATYFGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLAHLHANKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACEHNSEATYDNRSDLWSLGITALEMAESQPPLCDMHPMRALFLIPRNPPPRLKSKKWAKKFQNFIETVLVKDYHQRPYTEHLLKHPFIRDQPTERQVRIQLKDHIDRCKKHKQQKEREDYRYSGSENEEEEHPVAGEPSSIINQVQGGDTLRRNFQQIQEGKTLTSPSPKDPREARERERERERVERERERERERERDRERERERERERERENRERENRNRGGAGAGGKESKRDKDEFVDPGPPARPPLPQRLIVVPDPPPPSRPLPLPPKEERKQATPPISSQQQHHHRQGHHGQQPPQQPPRNSQLFKQAQARKPEELDVLAAHLNELGLGGSSSAAGSSSSGAPSHPPYPVAPSRSNGNKAALPEPASQFAAAAAAREAAREASREAAPAAAQHSDSDNEEEPAVRGTRNDGTLLASDPPKPLPSEPSVAAIKEGTPMGAGAPNRPLPPTPDEDANERTLMKRHHMGTPGSRSSTVLPDLLSQASTPSGQRLDKSSSEEKQRSFLTFGFGASGGGVPPRRESNINVNVTPTSHDAVPDTPEIRKYKKRFNSEVLCASLWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTVSGKKNRVRVYYLSWLKSKILRTEGVGDQNIEKRNGWINVGDLQGSVHFKIVKYEKIKFLVIALRDSIEIYAWAPRPYHKFMAFKSFGDLAHRPLLVDLTIEEGTRLKVIYGSAEGFHAIDLDQSAVYDVYIPKHIQNAITPHTIVTLPNSNGMQMLLCYDNEGVYVNTSGKMLKNVVLQWGEMPTSVAFIGIGEIMGWGNKAIEIRNVETGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGGSTWQIYFMVLNKPGMANW
The following text describes a protein:
Function:
Reversible blocker of voltage-gated potassium channel Kv1.2/KCNA2 (Kd=65 nM) and calcium-activated potassium channels KCa2.2/KCNN2 (Kd=575 nM) and KCa3.1/KCNN4 (Kd=59 nM).
Miscellaneous:
MISCELLANEOUS: Negative results: does not inhibit the potassium channels Kv11.1/KCNH2, Kv1.3/KCNA3, Kv1.4/KCNA4, Kv1.5/KCNA5, Kv1.6/KCNA6, Kv11.1/KCNH2, KCa1.1/KCNN1, or the sodium channels Nav1.5/SCN7A and Nav1.4/SCN4A.
Subcellular Localization:
Secreted.
Sequence:
TFINHKCKSSSECLPACKAAIGRASGKCINSTCKCYY
The following text describes a protein:
Function:
N-acetyl-D-glucosamine binding lectin. Almost no hemagglutinating activity towards human erythrocytes. Low mitogenic activity towards human peripheral blood lymphocytes.
Sequence:
MKRSNSIAVMLVLVLSSLMLLLPVEGQGHEGHGVGEILLMGKLGAPVCGVRASGRVCPDGYCCSQWGYCGTTEEYCGKGCQSQCDYNRCGKEFGGKECHDELCCSQYGWCGNSDGHCGEGCQSQCSYWRCGKDFGGRLCTEDMCCSQYGWCGLTDDHCEDGCQSQCDLPTLLPSPLRRIIAIRKLKANLANMLS
The following text describes a protein:
Function:
Involved in the regulation of calcium ion homeostasis. Binds to the calcineurin-dependent response element. Transcriptionally regulates pmc1.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MERQRSEEANRRFKDLNPSSLYDNLSKPDLGGSSELHTYMNDTSLADIPLFEDTLASEVSSSLISNPSKNNIQHLHPNTSEPFKTSSKSDEYDSYPRTGNVPTFSFTELNDTSVSGFGSQAVFENSVSPLSNPSNSPQAFDLTQGSSSTHNANDFTVNNVGSRRQSIYEFNIGIPSSNIDSSQFLPVSRAIAASEISPSSSPQLLTSFLPSGSVSNPSSPYLQGSVGALYEADAFNFVDVMSQASGTEVDSERFPSVDFEDPSLLMENQQNITGTGSFADYLQPPSSGSLGAFTNASPGESNTGIDFDTDNTNLNPSVDLLSNHSTPSFIFENSPSAEFSHQSSPYLVPNSGRTLNSENARESTIRSVNSPFSEDHADASLTTHVFDPISPTALSNSVLNYDSNNFSGTPQINVVPSSPSKSQSGPSLPANPLLQTDISITYSQSASPVSGQPAMNENSYDLQNANLCAPEMSPTYTARHRSNSAGSRFDAYEPIPQLYTHFSHSSECLSVNQDTELLGKIENDNSKSNDYLSVRNTRPRSRSLNSLVGNKSENSSSSKAKSESKSQGNYVCTFAGCNKRFTRAYNLKSHMNTHTNYRPFQCSICKKSFARQHDKRRHEQLHTGIKAFACVTCNQRFARMDALNRHYKSEVGQNCLRTATERGIQVPPSRKTAVASTSKQK
The following text describes a protein:
Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Subcellular Localization:
Late endosome membrane; Peripheral membrane protein.
Sequence:
MSQWSYNQYSHHGNRPAPNPKDEDDFSELLEDASKDELQMLIDNEDKILEIVMDDKKVKDMKMDNVMQQASNRSIADDNISKEPHLTQLRDALAEKYETLKQLNDTFLLNQAKLESLQKDTNLETTLAVLQTTCAQTEEESEELAEAFFAGNLSIGEFLTQFKAKRMLAHNRHIKTDKMKELVLEVQRQTSTPAVPPRNQPTNQTPAYPGSSRSASHHTPYSSGYGVPQQGKYPGTSFNQPTGQQYPGFNWK
The following text describes a protein:
Function:
Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds. May play a role in storage protein biogenesis.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MRARWAVTLLLLAVLALTASAARLDLDDDDDSGVLDELLAIDEEAERGGLLDAEGAGEAVRRAQSMVLALDNDNARRAVEDHAELLLLGYAPWCERSAQLMPRFAEAAAALRAMGSAVAFAKLDGERYPKAAAAVGVKGFPTVLLFVNGTEHAYHGLHTKDAIVTWVRKKTGVPIIRLQSKDSAEEFLKKDMTFVIGLFKNFEVLGADHEEFVKAATTDNEVQFVETSDTSVAKVLFPGITSEEKFVGLVKSEPEKFEKFDGKFEEKEILRFVELNKFPLITVFTELNSGKVYSSPIELQVFTFAEAYDFEDLESMVEEIARAFKTKIMFIYVDTAEENLAKPFLTLYGLESEKKPTVTAFDTSNGAKYLMEADINANNLREFCLSLLDGTLPPYHKSEPLPQEKGLIEKVVGRTFDSSVLESHQNVFLEVHTPWCVDCEAISKNVEKLAKHFSGSDNLKFARIDASVNEHPKLKVNNYPTLFLYLAEDKSNPIKLSKKSSVKDMAKLIKEKLQIPDVETVAAPDNVKDEL
The following text describes a protein:
Function:
ADP-ribosyltransferase that efficiently ADP-ribosylates one of the two alpha subunits of host RNA polymerase RPOA on an arginine located in the C-terminal region. ADP-ribosylation of RPOA alpha subunit enhances the transcription of viral early genes. Also ribosylates RPOA subunits beta, beta' and sigma 70 and performs an autoribosylation reaction. Additional in-vitro identified targets include proteins involved in either translation or cellular metabolism such as elongation factor-Tu or GroeL. Mono-ADP-ribosylates host MAZF which may inactivate the latter.
Subcellular Localization:
Virion. Note=About 25-50 copies per virion. This protein is injected into the bacterial cell along with the viral DNA.
Sequence:
MELITELFDEDTTLPITNLYPKKKIPQIFSVHVDDAIEQPGFRLCTYTSGGDTNRDLKMGDKMMHIVPFTLTAKGSIAKLKGLGPSPINYINSVFTVAMQTMRQYKIDACMLRILKSKTAGQARQIQVIADRLIRSRSGGRYVLLKELWDYDKKYAYILIHRKNVSLEDIPGVPEISTELFTKVESKVGDVYINKDTGAQVTKNEAIAASIAQENDKRSDQAVIVKVKISRRAIAQSQSLESSRFETPMFQKFEASAAELNKPADAPLISDSNELTVISTSGFALENALSSVTAGMAFREASIIPEDKESIINAEIKNKALERLRKESITSIKTLETIASIVDDTLEKYKGAWFERNINKHSHLNQDAANELVQNSWNAIKTKIIRRELRGYALTAGWSLHPIVENKDSSKYTPAQKRGIREYVGSGYVDINNALLGLYNPDERTSILTASDIEKAIDNLDSAFKNGERLPKGITLYRSQRMLPSIYEAMVKNRVFYFRNFVSTSLYPNIFGTWMTDSSIGVLPDEKRLSVSIDKTDEGLVNSSDNLVGIGWVITGADKVNVVLPGGSLAPSNEMEVILPRGLMVKVNKITDASYNDGTVKTNNKLIQAEVMTTEELTESVIYDGDHLMETGELVTMTGDIEDRVDFASFVSSNVKQKVESSLGIIASCIDIANMPYKFVQG
The following text describes a protein:
Function:
Ubiquitin-like protein involved in autophagic vesicle formation.
Sequence:
MESVASESAPKPKKITVKLKNIGDAPVLKNKKLVVKASDTLASLTKVLRKMLNLTLHDSLFLYIDTTFAPSLDSNFEVLARCYAVKTTGDEVVELQYSTTPAYG
The following text describes a protein:
Function:
Binds specifically to type I collagen.
Subcellular Localization:
Secreted. Note=Probably secreted from the basolateral region of the cell near the extracellular matrix.
Sequence:
MAKCLLLLLLVVLSSLLGLPQALECFQCNRVNASGVCETGGSTCQTQGSQQCFLRRIFENGTLSYGHQGCSQLCIPMKLFNPSVIVEYKCCHDSPLCNKF