lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Promotes programmed cell death. Its role in programmed cell death may be in conjunction with cell cycle regulatory factor efl-1 and the synthetic multivulva class B proteins dpl-1 and lin-35, and is independent of the ced-1, ced-8 and ced-9 pathways.
Sequence:
METAPDEAPTEFLEPGEEIVENVIEEEVVHEEDVEHHEEDGEMIEVQHEEVLEEIVEEDGMMFDTDGRVIEYSDVMVYEEGTEVIEEYVEVEDLGDGRYAYVMTDDIGHRRLLKPHEVEAVKKMPGMMEEEVVMDDEKAPNTSYAAAQKRGRFPPQARSSLSPQKPRAAGAYMGPEAYYQQPKRMTHMAKVDVEKYSPVTPVNRRPLMDNAIFKSKLPRKSAPWQEETAANGGPQSTSLIRSPSPMLKEPLFDDNEIRFKCAECGDGFPVMDRLCDHMIKQHDCQTNVREVQFFADRDFENFLLKVEKATLGRDPEDAIRKKSRAGSSQLFVCNYMNKGRQKMAELVEVGIVGLSERPLEVCTAFVQKTHGYECIRVKYCDQHIHYDGNIGFRVPIAVKRRLFEMSFKRLPIPCMQIMLGLEAEQLLPHPTRFEEKLKNLSHVEIIELLQIINASLRKHQEVEPRGKKVPIKFETIKSSEGSQTLMVKRVTPPKKEHMDYDEPDPNIPSTSAQALGYNPDDDEGDDVPMMSREEEVLDDETGEESVMTEDCDGMMEDNMLYDPENNRDPLFDELTEVELGVLDAYEHDIEIALTEAQKKERTRLKAKFALNKVIGIYQTLDTATHGLTAGELHTDTINHLRDMASYVVELVCQIDAEVKVRRNPALRIDDVKRDMIAGIAMQERVHQPERRPRRSAAPASPAKPQYRPQPPARSHEEYTQRIMNKVKEYMPRRRPDAYDLQQGQQQSRLQMLREQTLLRAPLEEEKPPVATMAPVPDEHKAIPWTRPGRKRAMGPGEAATAPAKRRGRPTKKEEAAEAAAKLIQAENEMVVEEEEVEEPPVVEQEQVPKEKEVEVAEAEKLPEQVKTEPSVTPSSAPPTPATTATKTRTGRVVKPKKWDDN
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MLPPMEEVYAGRSIFITGASGFVGKVLIEKLLRSLPGIATIFVLSVLFNQLRRTFPQRLRKVVVIEGDISEDDFGISEENLKRVLSETSVVFHCAATVRFDDKLKKAADLNIRGVRRMVSLCQRMPKLDAFLHCSTAFANSDKPGSNITETLHPIDCDAHKLLTALENLEDSQINLIAGDLIKNHPNLYCFTKLLGEQIIVRDASNLPALIFRPSIISPVWKDGIPGWSDAFQGLTAMLGAVSDYVECETNFICSQRYSGAIPRYPMHSINPKTIMDCVPIDVVTSMMIVCTGHRMCFDNDSIPVYHCCTTDFNPLSLQILANIGQKYAMQYPTERLLSPPSFTLRGFPAIESYRHKFRATYVGPAMDGFSSILRQPPMWTKIYNKLRSAYEALIPFAQFYHFESPSIDKLKAMMTDDDKKIFDFDVRKIKWDDYGCDLIMGMKTFLMKDDVVDAHKIRLAKMNLLSHQLMGLLPLYAICYFISEVVTGSFSSWQIFLPLIIVVTLFTLKEWVTCTKIKSLDDYRDKIESIMGEPVSSMKPKKHINFNDDNPPPPPSFLLWDAFVSIMEFLMAIVAIMACGMLFSVALIPNKRDLSITTSGFKPEPVVPSRAVTATPKRPITIPERNDLPEIVDTSGWPFTSPNREQPFLKELAALNFTRPILRSSDYRLSGVDVPTLYEVHLSVKIRGREKELISHFEGKSRTHFSRVGAASNTLELNAFGLYINKPSLFCDGRNFQVLKFNRNDRKQSFIVTVQEEIANESNCILEVVWTGQATTDNVGVYETWYSLDDDSLSFSLATHGETMHTRKWMPCFDEPKYKVPFKLSIEHPSGMTALSNAPVVSIKEIGSRLLTSFSETWPISTYLYAFSVTDYVSNSTIVDGLPVSVYVPSPLEFHLPRLMKEVTEVIPMSLKVFKAVHLNKKLDFIFFPDHTSAMENPGHISLGWDFIYSTNTLVHEMMHQYFGNLITLEWWSDLWINEGFANFYEEVALTGSNSKWHLKNLREMRDSSMSGDVYDTSIPLHTQVDTFIESRYQFRLPYSKGGIIINMLRDFLGKKEFDGIVEKILNVRANSTLNFQQFLEYVGESGENKANNAVEIARDFLGQAGYPLLVVRHVNGSTVIRQVRAHKGFVDESQRDFDTRWTIPIHLTALDGSDSKTVVMTRDEPEINHSGIFIVDPRKVVNYRVIYEKKTYKSIHRSKLSDEDKDVVDMDLVVAAVLGYADIAASYDTIMRRGTEKILTFSNEYIINIFTRTDTNRAKTKVLLEKLSGHKIEKRHNTETRHEHKLRQRRGKSDHSDEDLSEREMEDLLNKRDSNNCTIILNKTRELSKYNKLDLKDQGIRRNVSSLNCLLRRFNNDEVKRWISNLFDNHDYTFHLGDQGRILELIKLKTSNNFVHDFIIDELPQRTNYYKIALLLALPKFETTHLEQLKRLITKQPEAASENWRDIAKIFELAHASRNDANILAPKLMKALKLLSGEKSEDDHK
The following text describes a protein:
Function:
Potential transcription factor that may play a role in the regulation of genes involved in cell cycle G1/S transition (By similarity). May bind to regulatory elements of genes (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MTTVRLHLRRIMCNSSRAQTAQHTEEERKRTIISLQGGKSFGRATTNDVIFLDGTEHVELEPQFISRCHARVHHTNQDGVEEYLVEDISENGTYINDRRLSKDKREILKSGDTIKFGHKNGSQHVADQKYDHPDADFAFCVEMSTAGEPAYQLVEQIRDSRVKVFAGTACAKDIGPREPSTTNKVLQQEADSTNGGPEMENNRASSASSATPEDTQMPSTSQYFCSIPKKTPFRKEFDSPLHNYIYRTSRHSPLYRKKLAEQAQRMAVKNGTFVNDSGVIELLSHLLDINVAYENLVTKNEKLEIIGTFCEKNKGSFKVDELSRRKEELAVMMEEEEPQTIEIRELLVSLSEKAQDVQSNDFTISASSAFTVISTSGVLCPTASLANESEDSYIQHLKSINISSEKSRKIADELKTVRNSEVAPIENKPLSPEMMVVLHRLVKAKEHNNKVAHVYTGNYASTVSRVMEMVPITSQVAVITTAGTPKHTSKGSAETAPMEVDDERHSASSGSTENNYRRRTDSEESEILDVVGTDEPDKDEKGGTETETPTPSPEDHGRQTQNKIDKNVRMSSTPRIDAQSTPSAVVSALPTPMNSPLPRVTSSKSAQDVSTPSTTPNPVSRSPDPVALVKDSVSSESTVSGIVSLEKIGSPAAQSVASVLPSVSNTTSSTSASLTTSSVAEEEETSSKENTDQKRAVDDSSDESARLVKQIKALSATPSSTPAESSKRKQKDTSSRKMKQLDESSADSDSEDDGRSGDKSTKRRDKARRSTRIGKSTPAKKVGKKEKVVEDEDETDDVQEEEKVTPRGGRRKNMKRTASQSAIKERKTKDKDVEPEEAPKKKRGRKKATPTEEEEPPKTEPSKERCGVAKGHCISAKYEKRKNLQWVSCSICNQWFHVWCVRLDNVCYREDETFLCCGSHPSKEAKDALAGRVYARYQAMPNKKPIPQASEA
The following text describes a protein:
Function:
Specifically deaminates adenosine-37 to inosine in tRNA-Ala.
Sequence:
MEKLGSVSFHQTVSDICMTHYERSLPRKGKPENGREWTLLAAVLQSNLCGSESELKVVSMATGSKCLGASKMSKTGDVLNDSHAEVLARRGFLRYLYHQLRCAMTGSHENSIFYQPGEDGKCKLKERVRFHFFTSQTPCGDASIFNKDDEASTDTKPTSQHDIGQNPQNIINKHSMSSLNKRKAEEKLNGSNLPMTQKMKLDSLQSISDHVVPQTQNHIERRSCCNHDQHAERCSTCPADDHQTALVPSARMMQDELVKVVTCTGTKVVPSSSPCINGMPGGRDSDEDGGCLSGTCPIDDELSVSCDTLNSPLELSSPGLDIKTSSLLHNESASEEVPPGQRSVHTRHTDASKLNSAIPLKRDIYRTDPQDQSCPRLDVKTSSVLPSQSASEDVPSGQSSVHTRHTDASKLNSAIPLKRDIYRTGAKPTPSGPQDQLADGEDYHTVGLLRIKPGRGDRTLSMSCSDKMAKWNVVGLQGALLSHLISEPVYLSSVTIGQCPFNSQAMHRAIIGRVQPVSNLPPGYHVNSPVVMQSNIIFKDSKKEVERRRDPSKGKMTPAGAAIIWSYVPDQPVDVTANGKRQGATAKRWNDPQSRSKNCRCHLFHLFKKLLAGVDRDKLPQTLQSHDDLKTYHDYKMAASHYQKAWTQLLKVFSSWARKPVEFSQFQ
The following text describes a protein:
Function:
Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation. Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (By similarity). Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
Subcellular Localization:
Nucleus. Nucleus speckle. Nucleus, Cajal body. Note=Colocalizes with EAF2 to nuclear speckles. Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes (By similarity).
Sequence:
MAALKEARSYGLSCGRVSDGSRVSVFHVKLTDSALKAFESYRAHQDSVSLRPSIRFEGSQGHISIPQPDCPEEVRAFSFYLSNIGRDSPQGSFDCIQQYVSSYGDVHLDCLGSIQDKVTVCATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYMGKKVQFRKPAPGAADAVPSRKRATPINLASAIRKSSGSGASSVVQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKDTLDSLLQQVASVNPKDGTCTLQDCMYKSLQKDWPGYSEGDRQLLKRMLMRKLCQPQNATTDSSPPREHGRSASPSQKRPTDFIDPLASKKPRISHFTQRAQPTLNGKLGAPNGHETLLPAPGPTPSDTLSSSHLPPRLEPPRTHDPLADVSNDLGHSTQDYKHQEATPAPAPHLGLPLLTDFPQAEQPTSSSHTHSRPKKKSKKHKDKERPPEERPPAPQPDAPTAPALPPDAPGLNGACDNEPTSSSETPDYLLKYPAISSSEQRQSYKNDFNAEYSEYRSLHARIEQITRRFTQLDAQLRQLSQGSDEYETTRGQILQEYRKIKKTNTNYSCEKRRCEYLHRKLAHIKRLIAEYDQRQLQAWP
The following text describes a protein:
Function:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSDQQLDCALDLMRRLPPQKIEENLTGLIDLVPSLCEDLLSSIDQPLKRATDPESGRHYLLCDYNRDGDSYRSPWSNQYYPAMDDGVVPSPELRELEIQANNAFDSYRDLYYEGGASSVYLWDTEEDGFAGVVLIKKIGDGSKKIKGCWDSIHVFQVLEKSNGRNATYQLTSTVMLWLETNKDGSGLMQLGGSLTRQAEQDCTVDDNNPHIANIGRMIEDMENQMRSVLNQIYFGKTKDIVNDLRSVKSLKEAQSHMQMQKDIAAALTLRNKKN
The following text describes a protein:
Function:
G-protein coupled receptor that plays a role in the regulation of circadian rhythms and energy metabolism. Participates in maintaining proper circadian gene expression in the suprachiasmatic nucleus (SCN), the locus of the master circadian clock in the brain. May function as a coordinator of aging-associated metabolic dysfunction, stress response, DNA integrity management, and eventual senescence. Upon binding to adropin, modulates mitochondrial energy metabolism via the p44/42-PDK4 signaling pathway, influencing pyruvate dehydrogenase activity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSTTTPLISGVFGEATEFVTSNTDMAIEGRLVTTELSTSPWEQPTLPGPDPGTTPQNQDQDNIVMTFGTVMGTIAASLMCMTCIFGNILVVTVVQRSRRLQSTTNYFVISLAIVDLVMSVLCMPFMIGLIIADEWVYGVFICKLVRFLQYMKPGATVYVLIAIGVDRFYTILYPLSFKITRGKAKKMIIISWSIATLISCPAFYFFMLTELAGNKTVCTPFVSFEAAGIMYITALLLIEFILPLVLLLITYARIFRHIWTVGIRGRALQRTMNSVPRAKVKTVKMLMIVSSVFFVSWTPFFVVQEWFTCAKDMSEISQSEVNIYWATVWVSLTSCAWNPVIYSCYNPNFRRGCKEVFCVSTMKCYRKDTYAITNSSKFSRKNHVGVLTEDVDGGRSFTSYRAFDRDANGDKKMAWPLPTTTSTTYL
The following text describes a protein:
Function:
Cell surface proteoglycan. Regulates non-canonical Wnt signaling, being necessary and sufficient for fibronectrin-mediated translocation of dvl2/dsh to the plasma membrane. Required for proper convergent extension movements during gastrulation, which shape the neural plate, and for subsequent neural tube closure.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MSPTLMFVLLLCGVAAESIRETETMDPTSMLEYESSGSFPDEVFDDDEIDEDDDYAIDEDDEDYSGSGTDKFDIDDNDEDEEEEETATLGNQIPELDFDQTKTGRKIETNEIDNEIWSPTKPKILEPSNEISMASTGSEGFFQRTEVIVAIVAGTLVGLVVAISFIVFLVIRRNQNGDLVKKPIYKKTSTMEV
The following text describes a protein:
Function:
Required for the inhibition of NifA activity in response to oxygen and low level of fixed nitrogen.
Sequence:
MTLNMMLDNAVPEAIAGALTQQHPGLFFTMVEQASVAISLTDARANITYANPAFCRQTGYSLAQLLNQNPRLLASSQTPREIYQEMWQTLLQRQPWRGQLINQARDGGLYLVDIDITPVLNPQGELEHYLAMQRDISVSYTLEQRLRNHMTLMEAVLNNIPAAVVVVDEQDRVVMDNLAYKTFCADCGGKELLVELQVSPRKMGPGAEQILPVVVRGAVRWLSVTCWALPGVSEEASRYFVDSAPARTLMVIADCTQQRQQQEQGRLDRLKQQMTAGKLLAAIRESLDAALIQLNCPINMLAAARRLNGEGSGNVALDAAWREGEEAMARLQRCRPSLELESNAVWPLQPFFDDLYALYRTRFDDRARLQVDMASPHLVGFGQRTQLLACLSLWLDRTLALAAELPSVPLEIELYAEEDEGWLSLYLNDNVPLLQVRYAHSPDALNSPGKGMELRLIQTLVAYHRGAIELASRPQGGTSLVLRFPLFNTLTGGEQ
The following text describes a protein:
Function:
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
Sequence:
MHEIYLVDGSCFIYRAYHAIKGLSTSRGIPTNAIYGFTRMLLKLLREKNVKYILCAFDSPHPTKRHKIYEEYKITRPETPKDLPVQIDYIKQIIDALGITRIEVPGYEADDIIATAVGVINQFAPLNFIIISIDKDMLQLVSDNVKIYDPINELIIDREYVIKKYGVPPEKLNDFMALVGDAIDNIPGVKGIGEKTAANLIKRYGSIENILKNLDIIKPLKVSDIIKKNIKSLQLSKELVILRKDTPIEIKLDDLKIKQQDREKLVQIFRELEFNTLLKQIIKDFPNHSSCSVLQLNLASENRRNTIELIEKIKEYGKFSVTFNKDSIIAGVNGTLYEIAFNDTRVNEILSSEILKIIYNAKEALKKLKNSGLKLSPPYFDLMIVAYLINPNRGKYNIDELILEYTGKFYENAENINFYMFELYEKLNKELKEKELENLYFDIEMPLIEVLFDMEETGIKVNIEKLETLTKHISMELDKIKEKIYTIAGTEFNINSPKQLAEVLYDRLGLKTRKRGKKARSTEMEVLEELAIQHELPHEVINYRTLNKLLTGYLIPLRDYINPETKRIHTKWSQTVAGTGRIVSSEPNLQNIPVKGEWAEFLREVFIPENGYMFLSADYSQIELRLLAHMSEDPALIKAFLDGKDIHTATASEIFSIPENAVTDEHRRIAKTVNFGISYGISPFGLSESIKIPYEKAEELIELYFLRYPMVRKFIEETISFAQKNGYVRTLFGRIRPLPEINSPNQFLRMQSERMAVNARVQGTAADIIKIAMIRIYNRLKKEKLNAKIILQIHDEIVLEVEQKVIEKVSEIVQNEMKDFSLSVPLEVNVFSGNSLNL
The following text describes a protein:
Function:
Plays an important role in regulating the size of autophagosomes during the formation process.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MRAIVLLIGLIAYLALAEDYYELLGVDRDADDRTIRKAFKKLAIKKHPDRNTDNPGAHDEFVKINKAYEVLKDENLRKKYDQFGEKGLEDGFQGGNNYQSWQFYNDNFGIYDEDQEIVTLNRADFQRMVSDSNEIWFINFYSTYCSHCHQLAPTWRKFAREIEGTIRVGAVNCAEDPQLCQSQRVNAYPSLVFYPTGEFYQGHRDVELMVDFVIQRLKSEVLHLNSENWKALSEDWEPYNRLPWIVDMCGGDNIECLSSTTRRKLSSMLDGLANVATIDCHSEEELCSKFDHSSGVMWFPARKLEKKSQINIESMDAQEITKHVIEYLEELPWIEADSLQRFLEGNDPDEAIAVWMLANEVQATQKKDFRRLPALIDNQIFSFDCSKSEICDDLVDKTKLPQFIVFKPTGGYEIDYAGAKDFHSASIFIREASKSHIHVLNRDSYEYAISGGEFYIIDYFAPWCPPCLKLLGEYRRFHTATSEDSILHTVAIGSLDCVKFKDLCQTAGVGSYPTSIVYTPDGKQHKLVGFHNLDYILEFLDNAMNPSVLEMSPEQFEELVINRKDEETWLVDFFAPWCGPCQQLAPELQKAARVIKNYDENAFVASVDCQKYAQFCKETQINSYPTVRMFPAKKTKQPRRAAFYDYPNHMWRNADSIHRWVYNFLPTEVVTLGNDFSSTVLDSSEPWIVDFFAPWCGHCIQFAPIYDQIAKELAGKVNFAKVDCDQWPGVCQGAQVRAYPTIRLYTGKTGWSRQDSQGYGIGTQHKEQFIQIVKQHLKLHDEL
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Miscellaneous:
MISCELLANEOUS: Present with 1470 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAKKKSKSRSKSSRRVLDALQLAEREINGEFDNSSDNDKRHDARRNGTVVNLLKRSKGDTNSDEDDIDSESFEDEELNSDEALGSDDDYDILNSKFSQTIRDKKENANYQEEEDEGGYTSIDEEDLMPLSQVWDMDEKTAQSNGNDDEDASPQLKLQDTDISSESSSSEESESESEDDEEEEDPFDEISEDEEDIELNTITSKLIDETKSKAPKRLDTYGSGEANEYVLPSANAASGASGKLSLTDMMNVIDDRQVIENANLLKGKSSTYEVPLPQRIQQRHDRKAAYEISRQEVSKWNDIVQQNRRADHLIFPLNKPTEHNHASAFTRTQDVPQTELQEKVDQVLQESNLANPEKDSKFEELSTAKMTPEEMRKRTTEMRLMRELMFREERKARRLKKIKSKTYRKIKKKELMKNRELAAVSSDEDNEDHDIARAKERMTLKHKTNSKWAKDMIKHGMTNDAETREEMEEMLRQGERLKAKMLDRNSDDEEDGRVQTLSDVENEEKENIDSEALKSKLGKTGVMNMAFMKNGEAREREANKETLRQLRAVENGDDIKLFESDEEETNGENIQINKGRRIYTPGSLESNKDMNELNDHTRKENKVDESRSLENRLRAKNSGQSKNARTNAEGAIIVEEESDGEPLQDGQNNQQDEEAKDVNPWLANESDEEHTVKKQSSKVNVIDKDSSKNVKAMNKMEKAELKQKKKKKGKSNDDEDLLLTADDSTRLKIVDPYGGSDDEQGDNVFMFKQQDVIAEAFAGDDVVAEFQEEKKRVIDDEDDKEVDTTLPGWGEWAGAGSKPKNKKRKFIKKVKGVVNKDKRRDKNLQNVIINEKVNKKNLKYQSSAVPFPFENREQYERSLRMPIGQEWTSRASHQELIKPRIMTKPGQVIDPLKAPFK
The following text describes a protein:
Function:
Component of chromatin complexes such as the MLL1/MLL and NURF complexes.
Subcellular Localization:
Nucleus.
Sequence:
MTSASTKVGEIFSAAGAAFTKLGELTMQLHPVADSSPAGAKWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKATVKRKVYEDSGIPLPAESPKKGPKKVASGVLSPPPAAPPPSSSSVPEAGGPPIKKQKADVTLSALNDSDANSDLVDIEGLGETPPAKKLNFDQDSLTLDSGLLMTSADPPLLSC
The following text describes a protein:
Function:
Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.
Sequence:
MDNSSRRIRFKTKDNVVLESSVAAMTKSPTVRDYLINTGGEPDSGEIYLENISARAMRIIIKWCEEHIDYPCIENSDDPMGKPTPTEFDRELLKVGNDLLHELLCACVFLELYGLMDQGSRCVSSQMRGLDVKQMRRFLGIPSDSESEDENEPGPSNGRRR
The following text describes a protein:
Function:
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
Sequence:
MSSPSPFPSAQPFGDPAAIRCERAASELRAGRPVLITDAQGHTRAVLGLDSSTAQSYTAFARAAQGRHYLFVTPTRAQVLGLVAPQGARVALASHDYDQLAALAYLRDTPVPSQWTPGDALDAGAVEIARLGLLLPAMLAVELPGEQDRAAFAGCQSLALDDLDSGCATSAAAGYELVTRSPVPLRGLGMSEFVVFRGGVAQRDQVAIVVGQPDLGSAVPVRVHSSCLTGDLFGSLKCDCGDQLRHGLAKLKELGGGVLLYLDQEGRGTGIASKMRAYGYQHAGLDTIDADAQLGFGPDERRYGSAVAMLRGLGISRIRLLTNNPTKAERLRAAGIVVEDRIPVTGDITPENEQYLRTKAARAGHALDVDALILAAQ
The following text describes a protein:
Function:
Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein.
Sequence:
MNWFKGEIAQAIVTSKAKQAIFVVYVYGKDDKSAQITELIDKEEIVKILGSDSFVAIKIEADSVPYQQFSQIYKQVPTPSVYFIGKQGVPIEIVTEVNDVKTFQEKLNSILQKGGLSPIASQSQDFITKEQAQNVVCENDVCTMKKDETPSTSQQAVAGKEDLTVEEKVERAKQLVELKREEKRKEEFEKEREKELERRKMGQNVQQLKRWQEDQELKQVLEEREREKRESQAARERVLAQIAQDKAERAAKFSPTATVQPQAHSSQSQSSPRPVNTNTARLQFRMPDGSTATNDFSSSDTLASVHAHIKANLHLPFSNYTLSTTFPRREFTEAENSQTLLQLGLVPTAVILILPVNRGVVATNTEGGFTGFLWTLITPILTLLGYLKTFVFGSAPAPSTSNDNKRAAEASSSDHRGQPKVRRGGETTVIRRQGNIHRLSNKNDSDDENNTWNGNSTQQM
The following text describes a protein:
Function:
Inhibits the protein phosphatases PP2C06 and PP2C09 when activated by abscisic acid (ABA). Together with PP2C53, SAPK8 and SAPK10, may form an ABA signaling module involved in stress response.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Sequence:
MEQQEEVPPPPAGLGLTAEEYAQVRATVEAHHRYAVGPGQCSSLLAQRIHAPPAAVWAVVRRFDCPQVYKHFIRSCVLRPDPHHDDNGNDLRPGRLREVSVISGLPASTSTERLDLLDDAHRVFGFTITGGEHRLRNYRSVTTVSQLDEICTLVLESYIVDVPDGNTEDDTRLFADTVIRLNLQKLKSVSEANANAAAAAAAPPPPPPAAAE
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion.
Sequence:
MPRVAPAPKLFSKPANFAGKVNQAKGKYGDSRCAGSTFLPQITGGQITMAGDAEVPVATSAVLMSAAKHIGKNCARENHAFLDCKRADETPESCLDKGEQVSRCVVSLLKELNGKCPKAFNAYVKCMDYRTNEFDLCRKEQAEFEKQCPL
The following text describes a protein:
Function:
Involved in a nucleolar function.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTQAEIVKCLREEYEIEHNKDQKPEKEDLPAITKKFYQRVLELLTIHKVPYSKQEDEETYEEYLLSDTEESGNKKKKQQGKLKNQDSDDEDVEARIASIKNKLRQKKGPTTERQQKRRESKKLKRSKGVQKLLLSSAKNLKNENVKHQKLKNGVVKSEQETEDSKEQIQPVKVQPVYNQEAKIVYSKVDFAANPGGKAKKSHQNPKEILKKLRDTKKHLTELREQGETDKAAEIQTDIAWRNAFDKVEGKKVKDDTKLLQKAIKKRRVEKKKSKTKWTERKQKVEHDKEKRQKKRQENLEKRSKDKKNRKLKTASKRGRIIPGY
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MRSRFHQLKKVKIRQTWNKINLYNLSRYKPRPEGNTFFQQKWKAKSLSRAYHGEQIREGQWTRMFRPRAKAVIPMDYKYLAEHDGSELAAGRGSGLEILKGAGSAAQFNRNQIPYMSMVYAPIERRLDTAIFRALFASSTRQARQFVVHGKVKVNGKKMPYPGYLLNPGDMFQVDIDRVLFATGAPKTADQIKSGRGLRRSLRAMNDQKAKNAAAKKEKEAAAAAAREEGGETTTPKETPESKEKDEKDRLRMEFRTLQEHADILLTDSQNSPSGKRKIALRKLKREVRATLSQLKRTSVADLTSILNSYTTKLAKSEDLETIAAEARAVINAEEEPDYREKLKFALQRAKENPIDESKPYMTPWQPRPYMSAFAFIPRYLEVNQKICGAVYLRHPVARPGLSEVPSPFSMELLQLAHNWYLRRR
The following text describes a protein:
Function:
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
Subcellular Localization:
Nucleus.
Sequence:
MSYSHQFASQNSTSSSRVSSLTRVRHDTPGVQVTGTLRLRAEGDAQNAGEEMQARHIRWSEDVVDNEGMGKKSSKGTFNANTRLQDFFGPSGKVVRNQNHRTPNLILIAIAKPRTRMTEEAADTQTIAMILLTSHREEDAPQMAIVMTTRKSSAGSLVPMHTKRCRNIQKADCDIIVGLKLGLTVIQR
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
Sequence:
MSITEHEKKIHGLVDVGNLAQWSASTEKTGFPISNVRDDDINTYWQSDGSQPHVLYAKFIKRVEIKYLSIYLMYSLDESYTPSKIRIAAGTGLHDLQPVVTTELEEQEGWLHIPVGDYGRNGLLETYMLQLSILSNHQNGKDSHIRLIKIYAPEAPQALAVDEIPYTSIQFHSRSQLR
The following text describes a protein:
Function:
Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule. Plays an essential role for the assembly of ODA-DC and in the docking of ODA in ciliary axoneme.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme.
Sequence:
MFDNEEGQGPKSTFTTYMAEGDQLFQRGEYVKAVESFTTALTLQPDDKNCLVSRSRCYVKLGDAENALKDAESSLKDNKNYFKGLYQKAEALYTMGDFEFALVYYHRGHKLRPELQEFRLGIQKAQEAIDNSVGSPSSVKLVNKGDLSFFHNGVHPQNLNPSNKKESKKHSKKTDKGEKTAKQLLGELYSDREYLKKLLQDEDLVKCKIRSGERVQDLIVGSISYLDTRMAFWQQQKPIYARQRDRKLMQQQWSKVLHKPPSDPTRYVLSSLEEIDTALSAGYTESGLNKARELMKVVKDWSEDALPNKNEVLGNLHSYIGNALMDLGNMDRALHHHEKDLELAKKCDLTDSKSRALDNIGRVYARIGKFQQAIEVWEKKLPLACGGLEKAWLFHEIGRCYLELKRYMEARDYGSRSLMAADDISDEKWQLNASVLMAQAELKLSNYKASVLHFERALERAKLLQDDSASEAIQKALCEARLRVTQ
The following text describes a protein:
Function:
Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway.
Miscellaneous:
MISCELLANEOUS: Present with 3570 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MPMVTVKYNFQLFKCKVSLNSTLNDVLHQSIQFFQLHTSSNDWSLIHLDKPVPLDLPWRLLNLPTGVNLELSKSSNFPVANKTNREDIPFNTIKIRFQIPGRDSVVKEMPSDQPIAPILRQMSGAAGDDFKIQVFSKIIEFKTIKDENLTLENLGIQEPSSVRLIFNNTSHSEGISANSAIHPKQTPPTMTNPETVASLPPHELHKPSVFLPSDEPLAVIKDQIEDEEDYELTVEQAKKYQKMLSSKAGTLGGPILTKRLREQSANNLPKKNKAISECLLRVKFPDRSHIQIAFKPNEDMRTVYNVVSQFLIDENMPFTLNQSHPFKPLAKDDKKLLDDLEFGSKTMLLFETNSNSNGPLIKAHLLEDAQKITHETRTTPSVNTINKSNPQGPSDNATSIKKTLNRVPKWMKLSKK
The following text describes a protein:
Function:
N-acetylglucosamine (GlcNAc) kinase that transfers a phosphate onto GlcNAc to generate GlcNAc-6-phosphate, which can be a precursor for glycan synthesis. Can utilize a broad range of NTPs, namely ATP, CTP, GTP, ITP, and UTP, as phosphoryl donors. Shows only low glucose phosphorylation activity. NGK1 may play a role under a certain condition as an alternative supply pathway GlcNAc-6-P as a precursor of UDP-GlcNAc (Probable).
Miscellaneous:
MISCELLANEOUS: NGK1 is phylogenetically distant from other know N-acetylglucosamine kinases as well as hexokinases; and the amino acid sequence identity with others is only about 20% or less.
Sequence:
MTIESTLARELESLILPADSIVNVVDQFQEELLSRLQTNTISMLPQCLVPDKRSRWNPEDKILTIDFGGTRLKFAIISLPQIVIEYNDAFELTYNIVDSNFFNQIIYTICTRLAANGYIKKKNESSEASKFFVSVTFSFPLNPEGEVVAMGKGFVMTDTLQGSTVKQLIQSSFHRIISENIEEFFCTMNVCHVINDAIAVSLTSKFICENDSISLIIGTGTNACFEVPYGYLPPFKRDALRETLPSSYNKETLNFKHVLINSEIGFIGKNVIALQPFDIHGAISYEMPLECVTSGKWLPLSLKNILLQYNIIPKNFPVEFNGELVCQLAEDCTNAWFENEHYALICQIARLLIKRAAFYVAAIVQAIDIITGCKNYNFIHIGYVGSFLHNSNFYREQIKYYSSIHIKLQFLNHSNLLGAAIATYLNKSDNQVQ
The following text describes a protein:
Function:
Calcium-regulated non-lysosomal thiol-protease. Involved in the organization of the actin-related cytoskeleton during embryogenesis.
Miscellaneous:
MISCELLANEOUS: This protein binds calcium.
Subcellular Localization:
Cytoplasm.
Sequence:
MDDLRGFLRQAGQEFLNAAGEAAMGAAKDVVGSVINEIFIKKEADTKRVLPSIKNMRVLGEKSSSLGPYSEVQDYETILNSCLASGSLFEDPLFPASNESLQFSRRPDRHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFEENYAGIFHFRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLKEAPGNLFTILQKAAERNSMMGCSIEPDPNVTEAETPQGLIRGHAYSITKVCLIDIVTPNRQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRKWEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQCTVIVALMQKNRRSKRNMGMECLTIGFAIYSLNDRELENRPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNNMEENDDHVGYGGKADTITPGFPTPKPIDPQKEGLRRLFDSIAGKDMEVDWMELKRILDHSMRDDLPKPVVFNRFSNNMAFETQAAGPGDDGAGACGLLSLICGPFLKGTPFEEQLGMNDQSNKRLIGDNPADGGPVTANAIVDETHGFSKDVCRSMVAMLDADKSGKLGFEEFETLLSEIAKWKAIFKVYDVENTGRVSGFQLREALNSAGYHLNNRVLNVLGHRYGSRDGKIAFDDFIMCAVKIKTYIDIFKERDTEKNETATFTLEEWIERTIYS
The following text describes a protein:
Function:
Serine/threonine protein kinase (By similarity). Required for embryonic skin development and correct skin homeostasis in adults, via phosphorylation of PKP1 and subsequent promotion of keratinocyte differentiation and cell adhesion (By similarity). It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MEGDGGTPWALALLRTFDAGEFTGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICREPVGLVMEYMETGSLEKLLASEPLPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQGNGLNGELIRQVLAALLPVTGRWRSPGEGFRLESEVIIRVTCPLSSPQEITSETEDLCEKPDDEVKETAHDLDVKSPPEPRSEVVPARLKRASAPTFDNDYSLSELLSQLDSGVSQAVEGPEELSRSSSESKLPSSGSGKRLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLLRRSKT
The following text describes a protein:
Function:
Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome (By similarity).
Sequence:
MTQTGKRQRRKFGRIRQFNSGRWQASYTGPDGRVYIAPKTFNAKIDAEAWLTDRRREIDRQLWSPASGQEDRPGAPFGEYAEGWLKQRGIKDRTRAHYRKLLDNHILATFADTDLRDITPAAVRRWYATTAVGTPTMRAHSYSLLRAIMQTALADDLIDSNPCRISGASTARRVHKIRPATLDELETITKAMPDPYQAFVLMAAWLAMRYGELTELRRKDIDLHGEVARVRRAVVRVGEGFKVTTPKSDAGVRDISIPPHLIPAIEDHLHKHVNPGRESLLFPSVNDPNRHLAPSALYRMFYKARKAAGRPDLRVHDLRHSGAVLAASTGATLAELMQRLGHSTAGAALRYQHAAKGRDREIAALLSKLAENQEM