lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. Nup189 is autocatalytically cleaved in vivo in 2 polypeptides which assume different functions in the NPC. Nup98 as one of the FG repeat nucleoporins participates in karyopherin interactions and contains part of the autocatalytic cleavage activity. Nup96 as part of the NUP84 complex is involved in nuclear poly(A)+ RNA and tRNA export (By similarity).
Subcellular Localization:
[Nucleoporin nup98]: Nucleus, nuclear pore complex; [Nucleoporin nup96]: Nucleus, nuclear pore complex.
Domain:
Contains G-L-F-G repeats.
Sequence:
MFGQNNSSGFGGGTGAFGQNNQQTGGLFGSNSNTPGNTLFGSQNTSTTGFGQNTTQPLFGSNTNGGLFGNRNNTTTTGGTGFGMSSGTGMFGQSNTPAFGGTNNATNPSGGGLFGSNTANNNANTGTSFSFGSNAGSTGFGNTASNTGTGGGLFGSQNNAGNTAGNTGFGSQGTGGGLFGSSTTPATTNAFGTSGFVSSNANAVNGTANPPYAVTSEKDPQTNGTSVFQSITCMPAYRSYSFEELRLQDYNQGRRFGNASSTNTTSAFGSTPAFGASTTPFGQNLSGTTNNATPFGTSNATNTTPGSGLFGGGSAFGSNTTNTGFGSGTNNASGGLFGQNNNTTSTPSTGLFGGSTFNQQKPAFSGFGSTTNTTNTGTGTGLFGSNNATNTGTGQTTGGLFGGAATGTGTGFGSSTGGFGSNTNNQPNSGTMGTGLFGFGANNNTANNNTAPTSTFGGNNSSNFSFGANNNAATKPSGFGFGSTTTTPASGGFSFGQNANNAPKPAFGSTATTAPKPAGTGLFGGLGAGANTNTATNATGTGGSLFGNANTAGSNMFGSANSSTPGTGLFGSTQTNNATSNTGTGLFGSNNANTTNTGGSLFNKPSTTTGGLFGNTTAQQPSTTTSGLFGASNTNNQAQTSNFGTGLFGGSQAGQQQQPLQASIDQNPYGNNPLFSSTTSQVAPTSIQEPIASPLTSKPTPKKAASLPQFWLSPRSHNTARLASISSFAKSAVMNSTSASGKPKSLHLFDSLNDDVLLSADAFTPRQNIKKLVITHKISKDDILQNGVKNGNDAKSDSKVQEKAPQNEADGSLKKDEHVVLSDDYWMKPSIEELSKYPKEKLCSVHQFSVGRTGYGQVAFLKPVDLSGFEKLEDIPGKVVVFERKICAVYPVEGSSPPLGEGLNVPAIITLEKTWPLSRETREPIKDPQNPRYIQHVKRLHRIKDTEFIDFNDGKWIFKVQHFSRYGLLDDEEEENDMSSTSNEAGNLKKYDQPNLKVSGKNDSFVTHHTPGAFPNDSKNKELNRHFLKVDDSAPLDDTFMSKKVKLDFSSDSNVSERGDYDDNAKKVDEVISIEKVDGYSKENNVPLSEDDLSNSSESSNESVYSLVEESDASLAADNMDIEDISEESDREELSSMRFGAQDFHGLVVTDNWRDQLNLSVQRSALIKAAFPESQSNANLKNSRGIYYNEHDLVTDIFGNQNLDTDRPWQSLDKPGAFIPSKFHFTANGSCIYVLKSSDVKIRSIYDFIPTKDPNGTKLLEYQLDQTEVYLDLSGTHAASPRSSMTVKPLSLCSSGYESIVWDLTSILFDPKNYSLPSELSSEAREVLYQKLVRESLSEWITKTLEHETTTLAKEAETSEERIYILLTGNLIGQACEEAVQSQNNRLSTLIPLVNSDVDIQQEVKQQLEEWRKHGDLPFINKFTRLIFELLSGNTDIAEGCGTKGDEDYVQSIPITKNMTWLRAFGLKLWYNTDISIGEAMQLYVESLQKFPEIMQKPIATSAVQGIEVYDIIYLLLKAYAMGTSLEELTIPESAKCSPLNYRVVWQLAIYLSKARSLCDFSDRVVDINMAEDLKPISVHSDQLTLAYASQLEASGQWLWSLFVLLHLENVETRTSTITSCLARNLRGGLGAGAVEMIEKLCIPESWLNEAKALYARYVGDHLNELYFLQEAALYEDAHKVLLDTLAPQAVISGNKTQLKKALEGFNGQTDGLASWRFGGQIYSDYLDLLEGNFDANQELKLFTLRKISVALKELNATNLLQKAALHKISRFVNALCNEESLTDAICNLPLPLADSLANLQNISVQF
The following text describes a protein:
Function:
Catalytic subunit of the CTDK-I complex, which hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit. Involved in RNA polymerase II transcriptional elongation and pre-mRNA 3'-end processing (By similarity). Together with ctk2/lsc1, required for the regulation of cytokinesis by phosphorylating 'Ser-2' residues found in the heptad repeats of the CTD. Required for nuclear localization of ctk2/lsc1. Positively regulates the septation initiation network (SIN) and promotes successful completion of cytokinesis in response to perturbation of the actomyosin ring. Acts in parallel to clp1 to promote actomyosin ring stability upon cytokinesis checkpoint activation.
Subcellular Localization:
Nucleus, nucleolus. Note=Localized to nucleus during all cell cycle phases.
Sequence:
MSYSKSTIYRRQGTEPNSHFRRTVEEKSQLSGTNEESLGGHTLSSNAFKNNSSSISPSSSAKDPREQRKRTFPLNDTHSSRARQHERPFRSRKSRRRKGKKAFSPRPGSPPSPSFYRSGSQKRARNLTTKDYFAKRSESSSSASVSPISPSANRNDSKRQASSFRRSPPSSVHMKPSAFNGRKVSRRPSSSPPPIPSIPHETTSSDTQKKSSVSSGFPENKHGKFHFHIPNERRSRFDQPPSKRMALTSTARESVPAPLPSPPSGPIYTYTYPKPAYEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNIVRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPDVHSWPEVKNLPWYELLKPVEEKKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHEYFTSESPPPEPAVILKNMQGSWHEWESKKRKSKR
The following text describes a protein:
Function:
Serine/threonine protein kinase required for state transition by phosphorylating light-harvesting complex II outer antennae (LCHII). State transition plays a central role in response to environmental changes and allows to adjust to changing light conditions via the redistribution of light excitation energy between photosystem II (PSII) and photosystem I (PSI). Phosphorylates the minor light harvesting protein LHCB4.2/CP29 and is involved in the light-dependent phosphorylation of TSP9. Acts as a key component of the long-term response (LTR) signaling pathway. Mediates phosphorylation-dependent PTAC16 subcellular localization to regulate plastid gene expression.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane.
Sequence:
MATISPGGAYIGTPSPFLGKKLKPFSLTSPILSFKPTVKLNSSCRAQLIDTVHNLFIGVGVGLPCTVMECGDMIYRSTLPKSNGLTITAPGVALALTALSYLWATPGVAPGFFDMFVLAFVERLFRPTFRKDDFVVGKKLGEGSFGVVYKVSLSKKRSNEEGEYVLKKATEYGAVEIWMNERVRRACGNSCADFVYGFLDKSSKKGPEYWLLWKYEGESTLAGLMQSKEFPYNVETIILGKVQDLPKGLERENKIIQTIMRQLLFALDGLHSTGIIHRDVKPQNIIFSEGSRSFKIIDLGAAADLRVGINYIPKEFLLDPRYAAPEQYIMSTQTPSAPSAPVAAALSPVLWQMNLPDRFDIYSIGLIFLQMAFPSLRSDSNLIQFNRQLKRCDYDLTAWRKLVEPRASADLRRGFELVDLDGGIGWELLTSMVRYKARQRISAKAALAHPYFDRQGLLALSVMQNLRMQYFRATQQDYSEAANWVIQLMAKNGTEKDGGFTETQLQELREKEPRKKANAQRNALASALRLQRKLVKTVTETIDEISDGRKTVWWNRWIPREE
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Cytoplasm. Note=Localizes to the barrier septum and the cell tip.
Sequence:
MRIRSATPSLILLVIAIVFFVLAICTPPLANNLTLGKYGDVRFGVFGYCLNSNCSKPLVGYNSDYLDEHAKDGFRTSVIVRQRASYGLVIVPVSACICLISTIMTIFAHIGAIARSPGFFNVIGTITFFNIFITAIAFVICVITFVPHIQWPSWLVLANVGIQLIVLLLLLVARRQATRLQAKHLRRATSGSLGYNPYSLQNSSNIFSTSSRKGDLPKFSDYSAEKPMYDTISEDDGLKRGGSVSKLKPTFSNDSRSLSSYAPTVREPVPVPKSNSGFRFPFMRNKPAEQAPENPFRDPENPFKDPASAPAPNPWSINDVQANNDKKPSRFSWGRS
The following text describes a protein:
Function:
Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
Sequence:
ITCCSGIFLKYKEKAKMPATAEINCEGAARPEASDKDQCKACCQTEILHVVCDERAYLNQVEYILKTGARKGDRTGTGVISVFGSQARYSLRDQFPLLTTKKVFWKGILEELLWFIKGSTNSKELSMKGVKIWDANGSREFLDKSGFTSREEGDLGPVYGFQWRHFGAEYKDMHTDYTGQGVDQLQKVIETIKTNPEDRRIIMCAWNPKDMPNMALPPCHALCQFYVSNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHVTGLKPGDFVHTLGDAHIYINHIEPLKIQLQREPRPFPKLKILRKVDNIDDFRAEDFEICDYNPHPAIKMQMAV
The following text describes a protein:
Function:
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity).
Subcellular Localization:
Cytoplasm. Note=Localizes to the deuterosome.
Sequence:
MENQAHTTAGASPCEAELQELMEQIDIMVSNKKLDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLVMTQNYEGQLQTLKAQFSKLTNNFEKLRLHQMKQNQSHRKEASNKDETPFELSSLNQKIEEFRAKSREWDKQEILYQTHLVSLDAQQKLLSEKCNQFQKQAQNYQTQLNGKQQRPEDSSPETPRLVCESSPGCEATQRDEFIIEKLKSAVSEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKNELQSRDDLLRIIEMERLHLHRELLKMGELQTVQDNRKRVESSYSPSTKEPERKRKELFSVVSDQPNHEKELNKMRSQLYQEEDLCSEQERMRNEISELTQELHQKEVTIATIMKKAALLERQLKIELEIKEKMLAKQQISDRRYKAVRTENTHLKGMMGDLDPARYLTVDFSNKEHSRHTSINKLEYENERLRSDLAKLHINGKAAWSNQSSYEGAGAYIYQSQLKTETGGDRISEDCEMNRSPTPLSPLPFQTKEMTSPLAGDNEVLPLSPPDISFRASLAAQHFLMEEEKRAKELEKLLNTHIDELQRHTEFTLNKYTKLKQSRHI
The following text describes a protein:
Function:
Probable phosphatase.
Sequence:
MPSLKMKSKVSVSCLTETKDLHVCPKSKIISKSPCSKIMISTQKAEIDTTVQNCLDVSSRTQPKDVACDQSVDNKEFLDKENSESEQQFSVCSSVLGKMELTNACTANLETIFSPAFEPIEVHSQHYTEKDAVSICDTNMAGVGADEGRSICGYETCDVSDFYISDMIVTSLPFGGNSFDDDISETNCLSDYGSAEPSMFTASEQYMILPALEDDIKVGTSDIISYEEAVMVRESASLYSAIGQIRSCNQESNVKSDLDKSECFDPQSFIKNLPELSEIEVNGQPTLIPKQSPRRKSITLVLDLDETLVHSTLEPCDDADFTFTVFFNLKEYTVYVKQRPYLHAFLERVSEMFEVVIFTASQSIYAKQLLDILDPDGRFISRRMYRESCLFSDGNYTKDLTILGVDLAKVAIIDNSPQVFRLQVNNGIPIKSWFDDPLDCALMSLLPFLETLADADDVRPIIAKRYGLSGKSPSLIISIELSTFEVREENFIRLFL
The following text describes a protein:
Function:
Magnesium transporter that may mediate the influx of magnesium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDHDPKERLLLPPRAAAAAAANGPHRRAAPAAGGGGGGVAIDVHGLKRRGGGRRSWVRVDAATGASEAVEVAKPALMRRLDLPARDLRLLDPLFVYPSAILGRERAVVCNLERIRCIITADEALILRDPDVAGGGAETEEAVRRYVAELQRRLVDRADDLPFEFIALEVALEAACSFLDAQAVELEADAYPLLDELTTKISTLNLERVRRLKSKLVALTRRVQKVRDEIEQLMDDDGDMAEMYLTEKKRRMEASLLEEQAFQGMGNSGFGSSFSAPVSPVSSPPASRRLEKELSFARSRHDSFKSADSSQYSIEELEMLLEAYFVVIDYTLSKLTSLKEYIDDTEDFINIQLDNVRNQLIQFELLLTTATFVVAIFGVVSGVFGMNFEVDLFNVPHAFEWTLVITGVCGLVIFCCFIWYFKKRRFFPL
The following text describes a protein:
Function:
Elicitor of plant defense.
Sequence:
MEKLDKRREEETYLWIPVQFLDQALIAVLKCIGLLCQPAKKTAPSPVTFNQPEEQEEDYGVALKDDDVVVLLRDNKAKSKKRDKEKPSSGRPGQTNSVPNAAIQVYKED
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MRRGVSLRGVSGSSILMSPRWRVLGPEGNAGLRTAISFIGAGTLGAILIFKCAPKLILGRSLNSVSKIGATSSSPVEKMWTVPGLQNTGNNCFLNVILQALASSQALLNFMDRCAELITEAETKCQMTGSVDKVSMPLAVAVASLMKDLSQLGNVQRTSSPCPVMRALSLYVQHFDLASQQDAAEALIHLASALQEERGNYLKWLRPTLQSFVKAPGFSEACDSTHGRLECNSVKGSDQLLDSWRGRSWPLEGTIASSLTCQRCGYQFSTQFQSFNDITVTPSYDREGNMSRGCTLESCLDHFTRPEWVDSVKCSNCSHKSALLSIFLKSGEPMMTAAAASHTSNRKVSRSKVTYIEECGCDEDCNCELLTAEEGGVWRNVYTNASKQLKIGRCPEVLCFQIQRVVIGNDGTMKKLTGHVNFPRILDMFPYTVAAKESVPLSRGDHEESMQSRSSQSSVANHFAFVNKTLPHSEISCKGGADLGHPTAETCETLNSDGKEGAGEERSATRIVSEARTGNTETEFSPASGLLLGSVHTLNPSEKEEKLSGTLASEPVDVIGVRSRTDEESNLPCVNIDPACQELPEEGVFPVYSPAVELVTEIQPARYEESSTQPMSDIYVKKNSSSDLLLRNEEVSNHDSEIVDEVKSFDRFSTTNGGISLSTLNLNVAESVYSHYTPRVLPSILQQLSSFTIPYEGQQLSAGIHPYSKKLPGLPSMSKGSSRLTPRGYKYARKLPYELVSVVVHQGGPQNGHYIVYRKARLTGTKEKSLTKESVSLKHPTADGGGDTRESIVSGNKSVSEPQLAVKEPAAEGARLQSIYGQLIELESLPDITSSKRFEPSKSSVQISNDCGLSKDDLLHCVSTPDYSQVQPKRAAVSEDSTRCIGKSGRRDDGSVLWFRVSDTNVQRVHEQEVFGAHASLLFYEQL
The following text describes a protein:
Function:
Required for anaphase spindle elongation and microtubule bundling in both interphase and mitosis. Has a role in spatial and temporal regulation of septation and cytokinesis and ensures equal partition of segregating sister chromatids. Ensures correct midzone positioning of protein kinase ark1. Acts as a regulatory component at cytokinesis checkpoint where it inhibits nuclear division when actomyosin ring formation is impaired.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Localizes to microtubule overlapping zones during interphase and spindle midzone during anaphase.
Sequence:
MQTVMMDDIQSTDSIAEKDNHSNNESNFTWKAFREQVEKHFSKIERLHQVLGTDGDNSSLFELFTTAMNAQLHEMEQCQKKLEDDCQQRIDSIRFLVSSLKLTDDTSSLKIESPLIQCLNRLSMVEGQYMAQYDQKLSTIKEMYHKLESYCNRLGSPFVLPDFENSFLSDVSDAFTESLRGRINEAEKEIDARLEVINSFEEEILGLWSELGVEPADVPQYEQLLESHTNRPNDVYVTQELIDQLCKQKEVFSAEKEKRSDHLKSIQSEVSNLWNKLQVSPNEQSQFGDSSNINQENISLWETELEKLHQLKKEHLPIFLEDCRQQILQLWDSLFYSEEQRKSFTPMYEDIITEQVLTAHENYIKQLEAEVSANKSFLSLINRYASLIEGKKELEASSNDASRLTQRGRRDPGLLLREEKIRKRLSRELPKVQSLLIPEITAWEERNGRTFLFYDEPLLKICQEATQPKSLYRSASAAANRPKTATTTDSVNRTPSQRGRVAVPSTPSVRSASRAMTSPRTPLPRVKNTQNPSRSISAEPPSATSTANRRHPTANRIDINARLNSASRSRSANMIRQGANGSDSNMSSSPVSGNSNTPFNKFPNSVSRNTHFESKSPHPNYSRTPHETYSKASSKNVPLSPPKQRVVNEHALNIMSEKLQRTNLKEQTPEMDIENSSQNLPFSPMKISPIRASPVKTIPSSPSPTTNIFSAPLNNITNCTPMEDEWGEEGF
The following text describes a protein:
Function:
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
Subcellular Localization:
Chromosome, centromere, kinetochore. Cytoplasm. Nucleus.
Sequence:
MASSSCFQTLVSTEDALLQQLAESVLKIDCATELRVHLANSLPLPSNANRPRIDLIVFVINLHSKYSLQKVEESLNHVDSSFFLGKVCFLVTGAGRESHCSVHQNTVMKLAHTYRSPLLFCDLQVESFRAAMAQRLVRVLQVCAGHVPGISALNLLSLLRSPENPPSKEL
The following text describes a protein:
Function:
May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGKLHRGLAEFNGCASSIPPKYQTVIISNEEKKGFSSQSRRFEEYLNESPGPGSYLSHSPAEGCSPSFSKRGTGSFASKGGRVPRSFQRLSPGPDAYNLQMSLLHKHDFNRGESRIFRLPYALKKEKPNNENPAPNQYDVSYRAVDKNSTISGESAFRSKTRRSAVVSDKFKGPSPCHYKVSDVLVQKSPQALVSCFKSKTARIQSPVRNNIPGPGTYNPHQPPEPVKRTVLPRRYYLGLSAPPLIPEKVPPFPGPGHYDIVNYNRPVKHMVSSAAFLSGTNRHMQEVKGQDIPGPGFYEPTVLSKTSFLYNPAKLWIPA
The following text describes a protein:
Function:
Required for efficient biogenesis of the 60S ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSPPPPSQKTNRRKRRRRQLSISSSSDDDSSSDDEVATSTIQLASQEAMEVDGASSSASSSESSSSSSSDSSASESDSDSDADSGSESSAEIAKVVTAPGLAGQPKQRTRYPTNSPSPSPDSTLPPFFRSPAEGAELASLEERRNKFRTVYMNKIVEGFGGELEKMRESDPTLGPKRLQLLIDSLASGIDVYNQPKQTKRDDDVDEVTLLIGEES
The following text describes a protein:
Function:
Probable phosphatase.
Sequence:
MIHFEFHFIRMLFDLHFVFVSELNENKKFQLHEFYFRLCFGSPDSVPAAKMKAKTITTCKKDGNYPHVSQKSNKISKSTAVRATNEMASLAISSLTSQNDFCKNEEYSMDLDNKGDMGQTDISFNGCTDSMGQTEISFSGCTDSVVARDSLSSFLSSDSEAISPYNGPNYDQCQQFETVISEQFTWEPQLDVDDNFFSSFQMCDLDSSAYETGFPIIDELSSFDNSQSCYNLSDLLFPGINFTNDGTEENMEYPTLEETIGAADFTFGGSSEGFQQMFDSSWVNHLMCHQAIAFTEELTVSSSEISSDRVDYWDQETFIKGVLDLADDANSLPALLIDETSKRKKVTLALDLDETLIHSSMEQCDGADFTFKMITDRERTVYVRKRPFLQEFLAKVSEMFEIIIFTASKRMYAETLLDVLDPDKKFFSRRVCRESCTWKDRCCVKDLTVLGIDLAKVCIIDNTPEVFRFQVNNGIPIKSWYDDPTDSALMSLLPFLEKLVDVEDVRPLIAEKFGART
The following text describes a protein:
Function:
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
Sequence:
MAGVGIRSYACHRQTRRLLDGDVLMSPGPGNTDMPQTKSSPIAHPYPGRLITLDGIDGVGKSSQIEILAERLRSEGRNVLCVRDPGSTDLGTKLRAMLLDSDLEMHRRTEAMLFMASRCEMIESTLRSALADGVTVISDRFLLANVVYQSVGGEVDAQTLWQLGRLACGGVQPDVTLLLDLPAEISMQRVGGEADRMESRGVDYMAKVRQAFLDELPNAGGRTHVIDASGTIEEVAETIAAIELF
The following text describes a protein:
Function:
Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.
Subcellular Localization:
Cytoplasm, Stress granule. Nucleus, nucleolus.
Sequence:
MKNTMDQIKQNTDSLNARVDNLEEQISIIEDRQAEWRQTEEERELRIKKNEENLREIMDSMKSKNIRIIGIPENMEKENGAESVLNEIIEENFPNLGISGEMYVEEGFRSPRFVSVKRPTARHIIVKLANRNDKERILREVRKKKRITYKGAPIRLSADFSTETLQARREWSDIFKALKDKNLQPRMLYPARISFRYEGEIKSFPDKQKLREFVTKSPPLQEILKKALILEKRKKGERGHKPQTRETDG
The following text describes a protein:
Function:
Has a role late in meiosis.
Subcellular Localization:
Mitochondrion.
Sequence:
MTNYPFFRQGTIFVDNSAIQRNSENKNSLSIENIFGRFPKEFFQFFSINVSKSTTKKSSVVIKPSTITAPWLENEYLDSNTSLLSVHSIQPSFIGMSDFAIGLDPSLKRILPEIRFRLDFQHLKSIAKGATSTIKVVTHRDKITDAKIYYAAKVYRKTKTSHKKRLNTMVYFLREWSIQPKLDHPNILKVICPCVTLTSVFNKSAGFCLVQEYCPQGDLFKQIEEKVLTLEDKCCYLKQILQAVAYLQSQRIAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRFVSGAVGSLAYLAPEAFHENEYCGLLADRWSCGILLKVLFTGYFPFKTSVKTDLYYSKYMSILTDTCGISSTDESSFQTEVIKQIPTLQPLRYIPEGAKKIILSLLNPDSQNRPSLDSILGTAWVRKLDCCSNFSTDHENKSLQEVDFDASKPITRKSLIPRIHNHQTLV
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MAKKAKSRIINVRLISMAMTGYFYTFTRPRTSLPMSMLKYDPIVRRKVLFLEQKRKGRS
The following text describes a protein:
Function:
Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
Sequence:
ILLTSTSEVYGDPLVHPQTEDYWGNVNPIGVRSCYDEGKRVAETLMFDYHRQHGLEIRIARIFNTYGPRMNIDDGRVVSNFIAQAIRDEPLTVQLPGTQTRSFCYVSDMVDGLIRLMEGDNTGPINIGNPGEFTMLELAETVKEMINPEVKIVTVENTPDDPRQRKPDITKAKELLGWEPKIKLREGIPLMEEDFRQRLGIPSNKN
The following text describes a protein:
Function:
Legume-lectin receptor-like kinase required for normal pollen development and male fertility. Regulates pollen exine assembly and aperture development. Plays a critical role in annulus formation, and may participate in the formation of the fibrillar-granular layer underneath the operculum. May function by regulating the expression of genes involved in pollen exine development. Kinase activity is required for its function in pollen development.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytosol. Note=During meiosis, localizes diffusely in the cytosol and plasma membrane of microspore mother cells (MMCs). During tetrad development, localizes at the corners. At late tetrad stage, accumulates to the four corners of the tetrad, assembled into ring-like structures marking future aperture sites. When microspores are released from tetrads and preliminary aperture structures has formed, remains in a distinctly ring-shaped distribution beneath the aperture in the plasma membrane between the annulus and operculum.
Sequence:
MPPRCRRLPLLFILLLAVRPLSAAAASSIAAAPASSYRRISWASNLTLLGSASLLPGAAGVALTTPSRDGVGAGRALFSEPVRLLLPQDAAASASASRAATPASFSTRFTFRITPSPTYGDGLAFLLTSSRTFLGASNGFLGLFPSSSASDEGELRDVSTVAVEIDTHLDVALHDPDGNHVALDAGSIFSVASAQPGVDLKAGVPITAWVEYRAPRRRLNVWLSYSPSRRPEKPALSADVDLSGLLRTYMYAGFSASNGNGAALHVVERWTFRTFGFPNSSYAPPPTKYIGPMPPNNQPLPPPPSPSPSPPPPSPPPPPHPNHRRRHLFYKVLGGVLGGMVLLGLVVVGSAVLLGRSVRRKNQEHAVASEDMGEATLSMEVARAATKGFDSGNVIGVGGSGATVYEGVLPSGSRVAVKRFQAIGSCTKAFDSELKAMLNCPHHPNLVPLAGWCRSKDELVLVYEFMPNGNLDSALHTLGGATLPWEARFRAVYGVASALAYLHDECENRIIHRDVKSSNVMLDAEFNARLGDFGLARTVSHGGLPLTTQPAGTLGYLAPEYVHTGVATERSDVYSFGVLALEVATGRRPAERGISVVNWVWTLWGRRRLVDAADRRLQGRFVADEMRRVLLVGLCCVHPDCRKRPGMRRVVSMLDGTAPLILVPDKMPPVLLQPVPNASSMNSADTANTAFFSCR
The following text describes a protein:
Function:
Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLALIEAWAFGVVLYLFYLFLLWLWKERVETVLVGLFFGTLTAAQFIANKLVDFGVGVAPAGTVIFMTNVAILDVMALYYGRAFALRAVRLGFFFQAAVAFAAWSASVLPPPEWFASRAAVVDSVIAPSARIAVASLTAYIVSSTVDVYIVTRWPRLHVLLRAYSSSVVAQVVDTLVFISLAFGPEVEIIAGQVLVKWLQIPLEALLIYGARRYVATIKK
The following text describes a protein:
Function:
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MKSSLAFTATLLSSAHAFAPTSQWSRTSVSRNALIDDAFGVTNETGNKIPPLGRYILQDVNEDGIKWWQNAEIKNGRVAMVATIGYLVQKTGVHFPLYMGPNSSSDWLLSSTSGVTFGDVSHANALDTIAMVPSAGWLQVLFAAGLFELTAYKRQWMDGNEIPGDYGYDPLGFTKREGGWNSKELTDLRMKEIKNGRLAMITMAGWLSEESIPGSFPVWHP
The following text describes a protein:
Function:
Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
The DHHC domain is required for palmitoyltransferase activity.
Sequence:
MAVQLKWPILGVIIPCIIIFSLSYGSHYFILRHHLTMKQQLIYEFYVTMIWISYLLAIYTNPGRVPKNYKPSLASSTRIEQTEDDSDGLGLESREDETLIREEPISGDRCEWIRYCKKCNNYKPPRSHHCKICQQCVLQMDHHCPWTLNCVGNNNLPHFMRFLGWIIWGTGYLMIQLIKLIINYYENSNMPHYLFNKTELVAIIAITPLNFFVFASILVLFIRCLINICKGMTQIEIWEWERLELQWSSKRLWRLIRFNYGRLHKGKPFPELNTWTNTTNNVNYNDNDDDGDEDVELINLATNNNEDSTIVPQNFTIDDLIFPYNLGIWKNLVNALGYPYMWLIPFGKPKSNGYQPQISQDYKQDDQLNLPWPPDGIRQKEIEINVLQQQGYQRDREEEDEEELRSIRNYQELRRRLDPRLNVQRSDFINDMGEGLTDFGVDEDSD
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus envelope.
Sequence:
MATSLVTEDQDQSRTVENSTNLRCRKCRRCLIDTTSLLKVVTSTEAAATCNVWHLNIEFLPDWILASVDQASWTIGKLNCQVCRARLGGFNFINCSKCTCGLDTTVHLSKSRVDQDFKAPVMLTRPGRTREHDVGRRNNDAESQTISSSPSTSSNVSFSCTVPHVVSAAETEFESSREQQIPNTVERHTDLPLLYELPPQVSDYQERIEEQHADFDSRTSLDGAVDQEVVRLGVMEEPLRNVSPNLEPKLSKREKNRLKSLRRKQRKKERWVQRQQEAKDLAMKWDLTGSDDEERDGYTCAVCLDVYYSPYKCHPCNHVFCEPCLRTLAKNRPSNTPCPLCRTLISHVLFQEELNQTTKTCFPKVYRSRHETFQKINYSKWPLPNCPKRFRIFWGFQRHGGPANRWQFPHRAFGLDALDWGDMWGWPFDIDFVIISVYSLHWVMAFIIFCGLCYFLLL
The following text describes a protein:
Function:
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Subcellular Localization:
Membrane.
Sequence:
MWTEEQWDMSGDMWFSQQAETSSSSSSCKGGALTLNLWTPQFWRGHSFLGQPSPPEASSCRHNVEEGYIGLFFSPPNPHLPFSTDPHSLCYDITIIPKFRPGPRWCAVQGQVDKKTFLPYDCGNKTVTPVSPLGKKLNVTKAWKAQNPVLREVVDMLTEQLLDIELENYTPREPLTLQTRMSCEQKAEGHSSGSWQFGFDGQVFLLFDSENRMWATVHPGARKMKEKWQNDKDVTMSFRYISMGDCTKWLKDFLTGTDSTLEPSAGGNSRKKRGSGMRSEMVISRN
The following text describes a protein:
Function:
Catalyzes the conversion of L-aspartate-beta-semialdehyde (L-Asa) to L-homoserine (L-Hse), the third step in the biosynthesis of threonine and methionine from aspartate.
Sequence:
MKPVKVGICGLGTVGGGTFNVLERNAEEIARRAGRGIEVAQIAARRPNPKCDTGATPITADIFDVACNPEIDVVVELIGGYTLAHELVLKAIENGKHVVTANKALIAVHGNEIFAKAREKGVIVAFEAAVAGGIPVIKAIREGLSANRINWLAGIINGTGNFILSEMREKGRTFPDVLAEAQALGYAEADPTFDVEGIDAAHKLTILASIAFGIPLQFDKAYTEGISKLTSADVNYADALGYRIKHLGVARRTESGFELRVHPTLIPSDRLIANVNGVMNAVMVNGDAVGSTLYYGAGAGMEPTASSVVADLVDVVRAMTSDPENRVPHLAFQPDALSDHPILPIEACESAYYLRIQAKDHPGVLAQVATILSERGINIESIMQKEAEEQDGLVPMILVTHRVIEQRINDAIAALEALEGVSGPVVRIRVEQLN
The following text describes a protein:
Function:
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity). Involved in germline proliferation. May be required for both mitosis and meiosis in germ cells; [Isoform a]: Does not regulate the mitochondrial unfolded protein response following mitochondrial stress; [Isoform b]: Plays a role in mitochondrial unfolded protein response. Upon mitochondrial stress is exported from the nucleus where its tRNA endonuclease activity is negatively regulated. In response to mitochondrial stress, might be involved in activating a transcriptional response in an ATFS-1- and DVE-1-dependent manner. May play a role in negatively regulating the mitochondrial membrane potential.
Subcellular Localization:
[Isoform a]: Mitochondrion; [Isoform b]: Nucleus. Note=Accumulates in the nucleus upon mitochondrial stress.
Sequence:
MLGAIARKTVENRILVSRHLISSTSCLFKDNNEELLESIKERIARNRRILQKHSSSHLKAREVNASISNLRQSMAAVQKKQKAAHEPPANSIVNIPSQVSIEVLGNGTGLLRACFILRTPLKTYMFNCPENACRFLWQLRIRSSSVVDLFITSANWDNIAGISSILLSKESNALSTRLHGAMNIKHFLECIRPFQDSDYGSCKYPSQVEERPYTMENYEDAGLKVTYIPLSPPLNIGSNNEKSKNVKVNNVDIAFLIEMKEAARRIDTMKLMELKVPKGPLIGKLKSGEAVTLPDGRTIQPDQVFSSDKVEGDKPLLLVTECTTEDHVKALIDSSSLQPFLNGEKQLDYMVHISDDAVINTPTYRHLMEKLNNPSITHLLINGGNPVIPAVESVYKHTRLLRSIAPSLFPALHPIDWSGIITQNEELSQRQDQFIRVAPMQRYWMRRGASFNEEPIVNNLLAAEPELSDKAKELIKEYQKLEKENKMDCEFPKLTFFGTSSAVPSKYRNVTGYLVEASENSAILIDVGEGTYGQMRAVFGEDGCKQLLVNLNCVLITHAHQDHMNGLYTIIARRKEAFESLGAPYRPLVLVCNRNVLKPMKTYSICFENIEHLLEIVDISRYPLTPPGSPGGPPGKRPRLPSPHLPPSRDVLQDMSSSFDKKAWKLDELKAVQVHHTRMANGFVMRVAGKRIVFSGDTKPCDLLVEEGKDADVLVHESTFEDGHEADAMRKRHSTMGQAVDVGKRMNAKHIILTHFSARYPKVPVLPEYLDKENIGVAMDMLRVRFDHLPLVSKLLPIFREVFVAELFELTIKKEQRVLKDKELSEKRGQLKA