lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Regulates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths signal, depending on the cellular setting. Involved in formation of promyelocytic leukemia protein nuclear body (PML-NB). Involved in apoptosis involving PAWR which mediates cytoplasmic relocation; in vitro phosphorylates PAWR. Regulates myosin phosphorylation in both smooth muscle and non-muscle cells. In smooth muscle, regulates myosin either directly by phosphorylating MYL12B and MYL9 or through inhibition of smooth muscle myosin phosphatase (SMPP1M) via phosphorylation of PPP1R12A; the inhibition of SMPP1M functions to enhance muscle responsiveness to Ca(2+) and promote a contractile state. Phosphorylates MYL12B in non-muscle cells leading to reorganization of actin cytoskeleton such as in regulation of cell polarity and cell migration. Positively regulates canonical Wnt/beta-catenin signaling through interaction with NLK and TCF7L2; disrupts the NLK-TCF7L2 complex thereby influencing the phosphorylation of TCF7L2 by NLK. Phosphorylates RPL13A on 'Ser-77' upon interferon-gamma activation which is causing RPL13A release from the ribosome, RPL13A association with the GAIT complex and its subsequent involvement in transcript-selective translation inhibition (By similarity). Phosphorylates STAT3 and enhances its transcriptional activity (By similarity). Enhances transcription from AR-responsive promoters in a hormone- and kinase-dependent manner. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis.
Miscellaneous:
MISCELLANEOUS: A species-specific loss of a key phosphorylation site in murine DAPK3 seems to direct it mainly to the nucleus which is proposed to be compensated by the interaction with PAWR to maintain at least the cytoplasmic basic membrane blebbing function in the apoptosis pathway.
Subcellular Localization:
Nucleus. Nucleus, PML body. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center. Chromosome, centromere. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Midbody. Note=Predominantly localized to the nucleus. Relocates to the cytoplasm on binding PAWR where the complex appears to interact with actin filaments (Probable). Associated with the centrosomes throughout the mitotic cell cycle, with the centromeres from prophase to anaphase and with the contractile ring during cytokinesis.
Sequence:
MSTFRQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKVRRREDGARKPERRRLRAARLREYSLKSHSSMPRNTSYASFERFSRVLEDVAAAEQGLRELQRGRRQCRERVCALRVAAEQREARCRDGSAGLGRDLRRLRTELGRTEALRTRAQEEARAALLGAGGLKRRLCRLENRYDALAAQVAAEVQFVRDLVRALEQERLQAECGVR
The following text describes a protein:
Function:
Cilium-specific protein with a role in cilium/flagellum formation. May be involved in transport of components into the growing cilium. In germ cells and sensory neurons, plays a role with Cby in the building of the transition zone necessary for the formation of the ciliary cap and for the correct elongation of the axoneme.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Co-localizes with the pericentriolar material (PCM) protein cp190 at centrosomes in undifferentiated sensory neurons. Localizes to the ciliary base, including the basal body and transition zone in sensory neurons and germ cells.
Sequence:
MDLCLKGSQINLATRQKTKPKYTSRSLTTLHNPCPHFRPRSANFLQQRSRSSPFLGRPQSADPKFGRRLSNYFVEKELRNGGKRQVSSNDLLKSLLEEPIKRSWLCRSTCNSSESDYSLHKRTPDSSEEGEQFLVNMPVGEKVKSYSSYSGNQGLSNGALLQRTAKPDLPGRVSFSKPNMHADLDSSDCDNDKQEVRPSISAPGPLTLPSFLSKVEQADPVGQKKSVHFGSTAAEGEVLAETYEYPKCPSENCTCSTRSSSTTSTNEASASDVKCACDAPSCRFMESSKQVEPTSPTPTLPKAPSSELDVIREYKQAVEGVQVVKNHLGTDTLNNIEILPNYLDKYASPTKEKQNNLSETKNMATNSSAVNNGSVVYRPVGNPRNFGAENNFLPAVQDDRRSFANGSSDGVINNYLKVASTPPFVGKKKENVKPASADPIARSSKSKVTKSTINPAPLGKMKKAISVGSLREERKLSEYNLDKVDSWMSMQDQKQYDGKHKPGLEDLDEAQDNDTASQLSLKSNEDSRDSTYDEIVSVIKEIEEDKKRDNFSEGIPSELNLNLDSRCETADTVTVSEGKVPESGDKYKDILAYLNNVESSCDKTLMETRRSIPDSNRSEVEFVVEPDVTDEVPKLSELLMLPNHQLARRVIALSLRANELANAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNAVIRQQRKDYCVK
The following text describes a protein:
Function:
Participates in the repair of X-ray-induced damage to DNA and in meiosis. It may act in part by stabilizing a repair complex of other RAD genes.
Miscellaneous:
MISCELLANEOUS: Present with 238 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MPRALSIKFDNTYMDLYDELPESKLLYDEEFSYLLDAVRQNGVCVVDFLTLTPKELARLIQRSINEVFRFQQLLVHEYNEKYLEICEKNSISPDNGPECFTTADVAMDELLGGGIFTHGITEIFGESSTGKSQLLMQLALSVQLSEPAGGLGGKCVYITTEGDLPTQRLESMLSSRPAYEKLGITQSNIFTVSCNDLINQEHIINVQLPILLERSKGSIKLVIIDSISHHLRVELQNKSFRESQENKNYLDRMAEKLQILAHDYSLSVVVANQVGDKPLANSPVAHRTYVTDYDYQLGWLVGWKNSTILYRQMNSLLGASSNNDEILSDDEDYMLIERVMSTVNDRNYDFFSKKKPPIIENKTVERNSSSPISRQSKKRKFDYRVPNLGLTWSNHVSTRILLQKSFKASTIIQRGEAHLYKGGDSASFWQVKRTMKVVYSTFAKPGQIAYQITKRGIETA
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MKAQGETEESEKLSKMSSLLDRLHAKFNQSRPWSETIKLVRQVMEKRVVMSSGGHQHLVSCLETLQKALKVTSLPAMTDRLESIARQNGLGSHLSASGTECYITSDMFYVEVQLDPAGQLCDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSLEQDLSKMAIMYWKATNATPLDKILHGSVGYLTPRSGGHLMNMKYYASPSDLLHDTTASPITLHEKNVPRSLGMNASVTIEGTSAMYKLPIAPLIMGSHPADNKWTPSFSAVTSANSVDLPACFFLKFPQPIPVSKAFVQKLQNCTGIPLFETPPTYLPLYELITQFELSKDPDPLPLNHNMRFYAALPGQQHCYFLNKDAPLPDGQSLQGTLVSKITFQHPGRVPLILNMIRHQVAYNTLIGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLYKGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNLPPASSPGYGMTTGSNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEMCSGSNKTKKNKSSRVPPDKPKHQTEDDFQRELFSMDVDSQNPMFDVSMTADALDTPHITPAPSQCSTPPTTYPQPVSHPQPSIQRMGRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPPIGTPVRDSSSSGHSQSALFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFPDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGMPMLGGDNGESKLKGSSQADTVDFSILSVAGKALGAADLLEHHSGSQSPLLTTGELGKEKTQKRVKEGNGMGASSGSGPGSDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSNRPFTPPTSTGGSKSPGSSGRCQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYSSSGSVSSSGSKSHHSHSSSSSSLSSASTSGKMKSSKSEGSSSAKLSGSMYSSQGSSGSSQSKNSSQTGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSISKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGSSHVSGTSSSSGMKSSSGSGSSGSLSQKTPPASNSCTPSSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPIDSQMGASTNSSNHPMSSKHNMSGGEFQSKREKSDKDKSKVSTSGGSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGDSGGEGLRPQIASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNVDSESESGSSIAERSYQNSPSSDDGVRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPENWSKSPISSDQTSSMTNNPILSADRPSRLSPDFMIGEEDDDLMDVALIGN
The following text describes a protein:
Function:
Could be involved in the assembly of outer membrane proteins. May indirectly influence the assembly of outer membrane proteins, potentially by altering outer membrane fluidity. Inhibits the assembly of mutant forms of outer membrane protein F (OmpF).
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MRRFLTTLMILLVVLVAGLSALVLLVNPNDFRDYMVKQVAARSGYQLQLDGPLRWHVWPQLSILSGRMSLTAQGASQPLVRADNMRLDVALLPLLSHQLSVKQVMLKGAVIQLTPQTEAVRSEDAPVAPRDNTLPDLSDDRGWSFDISSLKVADSVLVFQHEDDEQVTIRNIRLQMEQDPQHRGSFEFSGRVNRDQRDLTISLNGTVDASDYPHDLTAAIEQINWQLQGADLPKQGIQGQGSFQAQWQESHKRLSFNQISLTANDSTLSGQAQVTLTEKPEWQLRLQFPQLNLDNLIPLNETANGENGAAQQGQSQSTLPRPVISSRIDEPAYQGLQGFTADILLQASNVRWRGMNFTDVATQMTNKSGLLEITQLQGKLNGGQVSLPGTLDATSINPRINFQPRLENVEIGTILKAFNYPISLTGKMSLAGDFSGADIDADAFRHNWQGQAHVEMTDTRMEGMNFQQMIQQAVERNGGDVKAAENFDNVTRLDRFTTDLTLKDGVVTLNDMQGQSPVLALTGEGMLNLADQTCDTQFDIRVVGGWNGESKLIDFLKETPVPLRVYGNWQQLNYSLQVDQLLRKHLQDEAKRRLNDWAERNKDSRNGKDVKKLLEKM
The following text describes a protein:
Function:
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
Sequence:
MSRHPLSGIVIAGGRSRRFGADKRRLRLWGDHGPHLLGHAIALLQPLCVDIIVVMNDGVAWPDLPARIVADEQPGSGALGGVISGLQAMHTAAALVIAADMPLIVPELLAALADWSFTGDVLAPTAPSSPDLPQPLLAVYRQSALAPLRQVFATGERRLQVALTSLRWVDPGPELWQRYDPAARSLVNINTPDDLAQIQHWLKKS
The following text describes a protein:
Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.
Subcellular Localization:
Cytoplasm. Late endosome membrane; Peripheral membrane protein.
Sequence:
MAAEEEAAPLSGVGWAAGPESAPAGWSVITTSVEGSAANLGKGFGHKGGYLCVSTAAPGSAGPVVTDVQVLSDRNPQPAGYSRAPEFPEPRSGVSRKKRLYVRLQPRGAAETAVFDIKLSGKSRAVPQYMKIGEIGSFAIWCKKGALPQCSPPPVPKPRTVSLGLKQLSLADSEQQAPGKPVAQSGSRHASFTLHNSADDGSSIYNLSAMDGVPFTLHPKFERSPKSDSSAILTDLTVKSLADIEKEQELKDAVCQQGKEEVCQQHLRDDDLELGNKRNG
The following text describes a protein:
Function:
Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
Subcellular Localization:
Secreted.
Sequence:
MPRGCALLLASLLLAAALSATLGLGSPVKEKRGWTLNSAGYLLGPHAIDNHRSFHDKYGLAGKRELEPEDEARPGGFDRLQSEDKAIRTIMEFLAFLHLKEAGALGRLPGLPSAASSEDAGQS
The following text describes a protein:
Function:
As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores. Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus, nuclear pore complex. Nucleus, nucleoplasm.
Sequence:
MNPTNPFSAPQPQPQPQPQPQPGAFPASSSASIGTFQAKPPFRFGQPSPFGQNSALPGKTAGFSQASGFPTASGGSHSASAQPLGFSQTSTVGLFPGLEHAPAFVAAAASASSSAPANPGFSFKSPSFGAFPSTSAFGPETGEIASSGFGKTEFSFKPLENSVFRPIFGAESEPEKTQNPITSGFFTFSHPISSGPGGLAPFSFPQVTSSSAANSNFTFSKPVNSNNSSSAFTSALSNQNVEEEKRGPKALFGASNSSFSSFPISPGPLAEAFPASKTGVRQGCEERVSQMDPHSSLMKGLKRKEEQDRSPRRHGHDAAEDLDALSRGDHPPDKRPVRLNRPRGGTLFGRTIQDVFKSNKEASRLGNKESKKDIGCVESGENDHVTIPGGSPSVLAPSRLPGVNKEEETESRDKKEDSLRGTPGRQSKRSESTDSLGGLSPAEITAIQCKNIPDCLNDRIILENHFGKIAKVQRIYTRRSKKLAVVYFFDHASAALARKKGKGLHKDMAIFWHKKKISPNKKPFSLKEKKPGDVEASHGPEDTPFQHSPLGKPVVRAAAGTLLNKSSPVKKPSLLKTHQFEGDPFDSGSEGSEGLGPCVSSLSTLIGTVAETSEEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCPDMCPEKERYMRETRSQLSVFEVVPGTDQVDHAAAVKEYSRSSADQEEPLPHELRPSAVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDPVTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLNLNKGDILREVQQFHPAVRNSSEVKFAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFNQIRKDALRALNIAYTVSTQRSTVFPLDGVVRMLLFRDCEEATDFLNYYGLTVSDGCVELNRSSFLEPEGLSKARKSVFITRKLSVSVGEIVNGGPLPPVPRHTPVCSFNSQNKYIGESLAAELSVGIPRPSVDAGGGGKGEACGVEADVLPPALLQQPLAVPAPIPASLPHLPAPAPSAAPSLFQAPGQPPTQPPVQPELLPPRPVPVYSDADLAQVVDELIQEVLQRDCEEVGAAGAAFAMTALGVSNAAMEELLTAATTGILRHIAAEEVSKERERKEEERRQAEEERLKQERELVLSELSQGLATELTELVVTECVRETCSQELKSAVETDQRVRVARCCEDVCAHLVDLFLGEEIFQTAKETLQELQCFCKYLQRWREAVAARKKLRRQMRAFPAAPCCVDINDRLRTLVPSAECPIAEENLAKGLLDLGHAGRVGISCTRLRWLRSQTAHQMKVQHFYKQLLSDAAWVPLDLPSLVAKHLPGRRERVFWKLVLVLPDGEEQGPGSPGRILANWLQVKFMGGDGSMDDTGSEPGGIQTLALFHALSSIGDQTVAVNVCIKVAHGALSDCALDAVETQKELLGASGLMLLLPPKVESEDMAEEDVYWLSALLQLKQLLQAKPFQPALPLVVLVPSPGGDTMDKEVEDGLMLQDLVSAKLISDYTVIEIPDSINDLQGTTKVSWAVQWLVSHCPCSLDLCCQTLIQYVEDGIGREFSGRFFHDRRERRQGGLMSQEPGAIIELFNSVLHFLASLVSSEQLCDLSWPVTEFAEAGGSRLLPHLHWNTPEHLAWLRQAVLSFQLPQMDLPPPGAPWLPMCSMVIQYASQIPSSRQTQPVLQSQVENLLCRTYRRWRSKSHPLDQGSGPSVAEIPWDDVISLCINHKLRDWTPPRLPVTSEALSEDGQICVYFFKNHLKRYDIPLSWEQARMQTQKELHLSQERLGIKSYHPAANTFPAPLLHVHQKGKRSVERGPEGRVPSTQDLMRGASAQELLAQCLSRSLLLEKEESKRFDDQLQQWLSADSGAFMDSMSLPLYLPQTLVSLPQSIDPVMKTVTPASPQNKRRGEQLQLSEATGTSVSERLKHLERLMQSSREEEVASELHLSALLDMVDI
The following text describes a protein:
Function:
Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II; Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II. Essential for vegetative cell growth and chromosome segregation.
Subcellular Localization:
Nucleus.
Sequence:
MGVPALFRWLTKQYPKIVSPVIEEQPREIDGQIIPIDIRGPNPNGEECDNLYLDMNGIVHPCSHPEDRPPPKDEEEMMLEIFKYTDRVVNMVRPRKLLMIAIDGVAPRAKMNQQRSRRFRAAQEAKEKAEDKAELLKMLKSQGTQAEETEVKKAWDSNEITPGTPFMDILAASLRYWIAYKLNTDPAWAKMKVIISDSTVPGEGEHKIMEFVRSQRSSPDHDPNTRHVMYGLDADLIMLGLATHEPHFRILREDVFFNDGKPRTCKLCGQHGHEARECKGMYKIKDGEFDEKASAPTLKPFIWLHVSILREYLAAEILEIREDGINTLIAIWRDNIPYMGGYLTKDGHVDLERAQFILDGLAKQEDAIFRRRRKAEENFQKKRKLNNERNERYGRGRGNNAGAQDSPSNGRQPPGGAAPTGLPLFTPGMANKEAKAISHDMVMNRGAAYKASIANKSAAAALKEMMNGKSTDDDNGEPRADDTSAELPATALGKRKAELIEDDDSSTPGRNSPIPGTPGTPTTPGDDLPPDTVRLWEDGYADRYYEQKFNRDPKDIEFRHQVGKAYVEGLAWVLLYYFQGCPSWDWYYPYHYAPFAADFANLKDMKINFQKGRIFRPFEQLMGVLPAASRQAIPEQFHHLMTNEDSEIIDFYPEDFIVDLNGKKFAWQGVALLPFIDSERLLDAMAKVYPTLPVDVSARNGLGKDVLLVSESHHALYDEITSKFYSKKQGSPHMKLNPKVSEGLTGRVEKNEDYLPYSSLVFPLESGAMPGLDEDRSIRVHYEMPKSNHIHKSMLLVGVDFGQPALNQSDIEMTKSRASRSGRNYGGVPLQGDGRGRNQFNYGSGNNNRGNGSRYNGPGTTAPRYNNQSHSSQNNYNNYSQPPPPPGWQPPPPGSYGGPPPPPPGSYGAYPPPPPGYGGGYNNYNNYGGRR
The following text describes a protein:
Function:
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
Sequence:
MITIKKGLDLPIAGTPSQVISDGKAIKKVALLGEEYVGMRPTMHVRVGDEVKKAQILFEDKKNPGVKFTSPVSGKVVEINRGAKRVLQSVVIEVAGDDQVTFDKFEANQLASLNRDAIKTQLVESGLWTAFRTRPFSKVPAIDSTSEAIFVTAMDTNPLAAEPTVVINEQSEAFVAGLDVLSALTTGKVYVCKKGTSLPRSQQPNVEEHVFDGPHPAGLAGTHMHFLYPVSADHVAWSINYQDVIAVGQLFLTGELYTQRVVSLAGPVVNKPRLVRTVMGASLEQLVDSEIMPGEVRIISGSVLSGTKATGPHAYLGRYHLQVSVLREGRDKELFGWAMPGKNKFSVTRSFLGHLFKGQVYNMTTTTNGSDRSMVPIGNYEKVMPLDMEPTLLLRDLCAGDSDSAVRLGALELDEEDLALCTFVCPGKYEYGQLLRECLDKIEKEG
The following text describes a protein:
Function:
Required for normal Golgi function.
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MAMNLKNSSSGGNLTSSPSYNSFSSLNLSGNSFNNGSGSGSGSGSGSNEYIPLCFSKDVFTSNTFEVDQFISDCRKRVNLESVQKDLREYSKHLDSELIELINKEYQSFFSLSTSLVGFDTILNEFSISQSSIKSEIKSFNNEIVKVRGLVEDKLNEKKSIEQKKKLLQLYISISETLNNMNHLFDQLYQLTHPNDFKKINNNNNNHTNNETNINDGDVLELLIDRISNSFYQIQNQMSSLTNDELKFNIFQSLSLKIMDLSNKIEEKVEPIFKESLKRFINVNNNNKEIVDDNNEKQNKYDERILLVCLKTFQTIDKLNVPYKLFKTLIVKPRLAQIVSLRNLEINKSTTDGLSQIYNSIIEFLKNQCSSFFDISNLINNNLKEKQSNNNNNNNNNNNNNNNNNNNNQINNNSNNNNNNINNNNINNNYNNNIILYNNYNFISQSVLPEIDESLGFFKQIFATGIPDLFYKNYYLTFNFIQSIEVNFLTNKELLTQFRQSSSYSSLWKKWNFAVYFQLCFTNIAQHFEFNYLRIPLFDQLTLPTNNITNNNNNNNENNNEFYLKSTDGLRLSMDKCWSNSNFIFDLSSKFFKLFLQLIARYDTFISDTLIPLELELQQQLQQQQLQQQQQQQQQQQNIGDSVIKITPKSPPSLSNQSPISSSTTLNNKQSSPENFIYIISDIYKIKSKISTNYKELIIKTIGNHQNQHEILNLINDGILESCKTLEQLIPRISIIIENHLISKCLEPIEIISTLRSTYRMTNKPVPTKPSIYVSNLISPLEILINNKASSLHFIPPEIKLNWAISVLTPVTESFKNAATNLIQSVTQSNDIINKMVKKSKPTTTTSGGDMSDMDKISLQLYLDVDKFGLYIQKFGINLLTFEPFLGLKSIVEPFKKLILNQNK
The following text describes a protein:
Function:
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
Subcellular Localization:
Cytoplasm.
Sequence:
MKVGVALSGGVDSAVALYLLLKEGHEVKAFHMKTKEDEFFIKKEIKKKVCCSPSDTADAMRIAHFLGVEIEIVDVKEIFREKVIEPFKRDLLKGLTPNPCAHCNRFVKFGYLMDYVLNQGFDAFASGHYARIEFSEKYGRKVIKKGVDLKKDQSYFLARIEPWRIERLIFPNGIYTKEEIRKIAEEAGIHVAKKQESQDVCFIPDGSIENFLKDEGITLKDGDIITPEGEVVGRHFGYPLYTIGQRKGFKIEKFGRRYYVRGKIPEKNVVVVSDLEDVFFSGLIAEDPVWHVEVPEEFRCVCRVRKKSEEAPAVVKVKDNEVEVSFEKKVFAVTPGQIAAFYDGDTLLGGAIIKEGIR
The following text describes a protein:
Function:
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MAISRLLVEKFRNLTAVDLDFDPCFNFLIGNNGSGKTSLLEAIFYLGHGRSFKSAVTNRIISYDEPHFTLFGQIQESQHQWSIGLQKLRQGNTLVKINGEDGNKISDLAHLLPMQLITPEGLTLLNGGPSYRRAFLDWGLFHHQTSFYSAWSNLNRLLKQRNAALAQNQPYSAIKIWDVELAKLAHQVSEWRAEYAEALSPEIEQTCQLFLPELEINVSFHQGWEKNADYYEILQQNFERDRALNYTFSGPQKADFRFKAQGLPVEDVLSRGQLKLLMCALRLAQGEHLMKEKQRHCIFLIDDFASELDQYKRALLAERLQQSGSQVFVTAITQRQLKEMQVENKKMFSVHNGIINALN
The following text describes a protein:
Function:
May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation.
Sequence:
MVGAMWKVIVLLVLLMPGPCDGLFRSLYRSVSMPPEGDSGQPLFLTPYIEAGKIQKGRELSLVSPFPGLNMKSYAGFLTVNKTYNSNLFFWFFPAQIQPEDAPVVLWLQGGPGGSSMFGLFVEHGPYVVTSNMTLRDRDFPWTTTLSMLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGESYAGKYVPAIAHLIHSLNPVREVKINLKGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKKYFQKQCHECIEHIRKQNWFEAFEILDKLLDGDLTSDPSYFQNVTGCSNYYNFLRCTEPEDQLYYVKFLSLPEVRQAIHVGNQTFNDGTIVEKYLREDTVQSVKPWLTEIMNNYKVLIYNGQLDIIVAAALTERSLMGMDWKGSQEYKKAEKKVWKIFKSDNEVAGYIRQVGDFHQVIIRGGGHILPYDQPLRAFDMINRFIYGKGWDPYVG
The following text describes a protein:
Function:
Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA.
Subcellular Localization:
Mitochondrion.
Sequence:
MALWKAVSLARVTATGMREAAPGFRCISAVPSSTPSAEDEVDTRENEIVAPDFTNRNPRNLERLALARKERGWRTTWPKQDYWHRLRLARSQKHVEAYVEHCSGHIVVSASTQEWAIKKHLHSTSNIAACENVGRVLAQRCLEAGIGIVDFRATIPWEKRSESVKRFENAMTEGGITLREVRRIYE
The following text describes a protein:
Function:
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
Subcellular Localization:
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Sequence:
MDENETQFNKLNQVKNKLKIGVFGIGGAGNNIVDASLYHYPNLASENIHFYAINSDLQHLAFKTNVKNKLLIQDHTNKGFGAGGDPAKGASLAISFQEQFNTLTDGYDFCILVAGFGKGTGTGATPVFSKILKTKKILNVAIVTYPSLNEGLTVRNKATKGLEILNKATDSYMLFCNEKCTNGIYQLANTEIVSAIKNLIELITIPLQQNIDFEDVRAFFQTKKTNQDQQLFTVTHPFSFSFDSKDSIEQFAKQFKNFEKVSYFDHSIVGAKKVLLKANINQKIVKLNFKQIQDIIWTKIDNYQLEIRLGVDFVTTIPNIQIFILSEHKNPVSLPIDNKSTENNQNKLKLLDELKELGMKYVKHQNQIY
The following text describes a protein:
Function:
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Subcellular Localization:
Cytoplasm.
Sequence:
MMKSRFCPSPTGLMHLGNARTALFNYLFAKSKDGIFLLRIEDTDVERSKETFDLGLQEDLRWLNLEWQEGPGADEGNGPYHQSKRQAIYDDYYQRLEEADQAYPCFCSEEQLRLSRKIQRSAGKPPRYAGTCRSLSAAEIEKKKAEGLQPALRFRVPDDEVVVFADLVRGEQRFQTNDIGDFIIRRANGTSPFMFCNAIDDALMGVSHVLRGEDHLTNTPRQLLILQALELPVPTYAHIALIVGPDGSPLSKRHGSRGIKELRDNGYLPLALTNYLARLGHYYASDELLSLAELAKGFNVESLSKSPAKFNAQQLDYWQKQTVNQLPNDDFWEWAGSELQSQIPTDKDDLFLTTVKPNVSFPRDVAYWVNVCFGKTLNLETAQSELLRATGNRYFEEAFEAFKKFGKDLNSVVSHLKEKLNLKGKPLYQPLRIALTGAEHGPELAKLILIMDYETIQNRLQEACQ
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1580 (Gm1580) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. Also required for formation of 2'-O-methyluridine at position 1579 (Um1579) mediated by MRM2.
Subcellular Localization:
Mitochondrion.
Sequence:
MLCNIFKRSLQANIRNVNNLNVLRLSSSSGPRGEIQDALDIEANLFGNSDLRHEPMNTREALRKNRFAGRKPKVPFASVASRNLSAPSNPAPRVAPTPAPVIKDNELNLEFVRLTLQDPLTSTLLTTVRSRKRRDKNRQIIVEGRRLIQEALQCGLKMEVLLFSQKDQLALVKEEVGVAQVETGTKIYKVPQHDLKTWSSLVTPPGLMAIFDRPSDKGLEKNLAEQQRLGSQPFPITVVCDNIREPNNLGSIIRTCAALPCSQVVVTHGCCDPWESKALRGGCGGQFRVPIRDDVTWDELALTIPPEAADDCHVFIAETNQRKRENNQTIDYADIKGLGAHNLLIIGGESHGVSEEAYRFLNLVGGKGKCIYIPLAAGIDSLNVASALTLLLFELRRKLIHQASEKE
The following text describes a protein:
Function:
Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MAASREFIICCFLTLLLCNFFMRVESGAAADVSRGGCGGGDGSLGDDNERCVEAVKEDDDDDVDDVYKVINKMRIYA
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MALNLLSIPPSYHGLIIQRIPLKTGLVPAEPLKTLAPSKSKLNTIEAKRIMSVLDEAINKVELITLMSYLESHPEALEDALPENFVEAIREHLDIGQALVEKASILQRKQKELEKGEEAEEDWDQERLLSIELHKTNLWPLTHQFRDSTKTILRLLINEPQLTRLLHTQAPGRSPGAQCLLTSLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSKRNQEIIDALQAELAEVLKNKEAEVEKENFVIQELKNHLHQVFKFSENSLLRTKQEAEKQQKVDYRASQARQAKTQQDILALRAQYHNLVMENREAEQALRKKKYKVETEIENWIQKYDMEMNEKQEEYEDLETIHKEEKLQLEELKERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAMWKGYLVRSMLRSRKKKRVKSKGKDKGKGKEKPKEEKGKEKKAKGKGKGKK
The following text describes a protein:
Function:
Peptidoglycan polymerase that is essential for cell division.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSALQLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGAYGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWRFVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTISLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNSIEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVALGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKRAKLYRELENQPMNLLLK