lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MLRAFRDAFRIPDLQRKIVFTLLLLAVYRLGGAIPTPGVNSAALSQANSGGLFGLISMISGGNLSQFSIFALGVLPYITASIVIQLLTTTIPSLEKLSKEGEEGRKKINQYTRYAAIALGAVQALFFSLYITSNPSFIAVGWDPGLFTVLVMVLTQVAGIAFTMWIGERITEVGIGNGISLIITAGIIAVYPREIAATAQLLRSEQTTLLSILAFIAVILVTIAGIVYIYQAERRVPVTYARARGGAAGQARGAGQATWLPIKVNQAGVIPVIFASAMLIIPNLIASATATRAPEVNAWINSNLTFGQPLYLALESLLIFGFTYLYNSVQFDPKRIAEQLREAGGFIPGVRPGGPTADFLGRISGRLSLWGAIFLVILTILPQLVQKATGITTFQFSGTGLLIIVGVALETLKQLEAQLTVRRYDGFISKGRLRGRLNN
The following text describes a protein:
Function:
May play an important role in innate immunity by mediating a signal for the production of a neutrophil chemoattractant.
Subcellular Localization:
[Isoform 1]: Membrane; Single-pass type I membrane protein; [Isoform 2]: Secreted.
Sequence:
MTQRAGAAMLPSALLLLCVPGCLTVSGPSTVMGAVGESLSVQCRYEEKYKTFNKYWCRQPCLPIWHEMVETGGSEGVVRSDQVIITDHPGDLTFTVTLENLTADDAGKYRCGIATILQEDGLSGFLPDPFFQVQVLVSSASSTENSVKTPASPTRPSQCQGSLPSSTCFLLLPLLKVPLLLSILGAILWVNRPWRTPWTES
The following text describes a protein:
Function:
Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.
Sequence:
MAGSGAAAIAAGTASPSIKSASTGTSYDGAGAPVVIPIKFALCDNVSTIYREMTRLLRHEFGAKRMKGTSTRLDLLLGDRNNPPYFRMGMMAATHGGLPPLINFYRGNDRLCQKAKMAQLLQGGTAAARPTWLPETYTVRGQRTEQPDHERDLLLLAHAQRPRVWIAKPTCGCKGENILIDDNLPRLLQAMDHYRFLFVVTEYLLEPLLLTPGGRKFDLRLWVLLDPQYEAFIFEEGVLRTASTPYTADSWDDVTQHLTNHAIQEVHAQDYERYEPGNELFFPDFRLWLQEHRGVDFDEEVMPQMAQIIHQCFDALRPSCQLPPGHAYHSFQLFGFDFMLDAAMKVWLIEVNGAPAAAARLTTPIAHDLCLHVAQYFGFVRHPKTRFKPVLDLM
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Sequence:
MLLPRYFCWNLQRCTMAFYAVASGRRSGVYGSWAECEEQVKGFKNAKYKKFKTRQEADQFVNGCKSYAPQDVAVPLGKEKASLASWKNSIEVNKNPKYTDEWPEEDHDLAEDDLPDILNRKRKGTTSGDKRNKIPRHASQVSEATGLKQVGAFQFEIDAEGYVIVYTDGSCIGNGRAGACAGYGVYFGKNHQLNAAKPVEGRVTNNVGEIQAAIHAIKTALDLGIQKLCISTDSQFLINSITLWVAGWKKRDWKLKNNQPVKNVVDFKELDKLLQENNITVKWNYVEAHKGIEGNEMADKLARQGSALYKQKNG
The following text describes a protein:
Function:
Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events (By similarity). Involved in apoptotic DNA degradation. Involved in regulation of antisense ribosomal siRNA production. Involved in response to cold-warm shock.
Subcellular Localization:
Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=As a part of exosome complex, translocates from the nucleolus to nucleoplasm in response to cold-warm shock.
Sequence:
MSGEESMPDEEQKQSEEEEEMIRKRTLAMRKKVEEIMRNGAGLVRESNGLPKAGADYELYNSYPTFNTFMKRSEQRLNALMNKVTKSIGCAMRVPDVGSSVEHYTECVIEAQDNIAERAATLHEALKKAELDEIVKVPEFITKAAPTNRKTEAEVSAAMRTFSANIGTVLAEKFRERREEAAQMVVLEKPQKTYNISSDNSQAPFSSKLTVKHHAIEKRTGIVLHDDDESGRRDWISAETETEEEHPYIAEILHFKVPEAQLKSAECLKFTALKDTPLTMIDTKEKLEALTKTLNSVKEFAVDLEHHQMRSYLGLTCLIQISTRDEDFIIDPFPIWDHVGMLNEPFANPRILKVFHGSDSDVLWLQRDYGVHVVNLFDTYVAMKKLKYPKFSLAYLTLRFADVVLDKQYQLADWRARPLRNAMINYAREDTHYLLYSYDMLREQLLKQDTKDLANVYSESSDLCIKVYKKPVFNPKGYLTEIKFRFTLNTRQDYALTHLFKWRDVVARAEDESPHFVLPNHMMLSLSETLPRDVGGIYACCNPLPYFVKQRTGDILKIIVEARDVKLEKVGLSAKERNDAQEARGVMNDTMDHITSVLKSKIDFSHTRFDEERGEIYIDKTDEGMDIELKDHKESLLSVLQTAEIPSVETMIVVEKGKKSDNQKVKKLLNELDKFVTPFECYQMMMITKEKQEEEERKEAERKKLEEGDLPKTMFSHHDAPINRKPEFDAKLLNVDTLKLVPDDPNKPKDPEPSPMEESSSEPQIFDPSRFTDDQLLSKKAMKRKRDAARRNIDVSVVLGESSSSSDPKKKKSDDDAPVEDFDYEKADSSAFEKPVRDNNADFDPFHQKYRLKNKTKKNMAMKKSSNRQGTINYKK
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MEDTTSTGTDTKLVFTDTDATTPTSTSTPNAGAEASQADLQAQLALFQQQQQQYIQQLMQQTNSEQLRAMYSSSAMMQPYMLSQSMFPRPTTPNSAETTEEEPVYVNAKQYHRIMIRRQQRAKLEAKLGNPRQRKAYLHDSRHKHAMRRPRGPGGRFLTKDEIQGLKDGTMVFEDLPRKAAPKQQ
The following text describes a protein:
Function:
Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type IV membrane protein.
Sequence:
MSWFADLAGKAEDLLNRVDQGAATALSRKENPSNIIYNKNADYPELQQNTDLTYQTESKATYISSAADNIRNQKATILAGTANVKVGSRTPVEASHPIENASVPRPSSQFVRRKKSEPDDELLFDFLNSSQKEPSGRVEIKKEKSKTPVFQSSRTATVSSMNTSKTTVKTIEENPPGSQTDETSNNSDSGHEVQEDSSKENVSSSAASTDHNPTPTHDGKSHELSNLRLENQLLRNEVQSLNQEMASLLQRSKETQEELNKARARVEKWNVDHSKSDRITRELRAQVDDLTEAVAAKDSQLAVLKVRLQEADQLLNTRTEALEALQSEKSRIMQDHSEGSSLQNQALQTLQERLHEADATRKREQESYKQIQSEFAARLNKMEVERQNLAEAVTLAERKYSDEKKRVDELQQQVKVYKSNLESSKQELIDYKQKATRILQSKEKLINSLKEGSGFEGLDSSTANSMELEELRHEKEMQKEEIQKLMGQIHQLRSELQDMEVQQVSEAESAREQLQDLQDQIAGQKASKQELEAELERQKQEFHYIEEDLYRTKNTLQSRIKDREEEIQKLRNQLTNKTLSNSSQSELENRLHQLTETLIQKQTMLESLSTEKNSLVFQLERLEQQVNSASGSNSNGSSINMSAVDSGEGTRLRNVPVLFNDTEMNLAGMYGKVRKAASSIDQFSIRLGIFLRRYPIARVFVIIYMALLHLWVMIVLLTYTPEMHHDQPHGK
The following text describes a protein:
Function:
May play a role in vesicle-mediated protein trafficking.
Subcellular Localization:
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MNNWKRFTFFDIETVKQVEKEDGSSLQKLSITCTTSGRGSLIIGDAEGFINFVDREFGISSFQAYQQSVSLIYQLKERNFLSSVGHDDIGGAAILKIWNLDKTDKNEQPICVRSIKLEKSVTVTCFTLLEDLSQIIVGLANGEIIIIRADIFRDKVIKQKIIKVPNDSPITGLGFFPTKSQQSASAGAVLFVVTTTHVITYHTAHKDQETIIDDEGGDIGSFLMSDDGSPIIARSDAIYFYNVDGRGPCFGFTGVKTKVLWFRSYLVVIGYDTNNTNALFPGAVVGGQNSIGGLGSQTGSIGSPSVMVQNTKNNVLNIYDLKNKYIGFTEKFDTVSHICSEWGSIFIFGADGKVFQLEEKDTQTKLETLFKKHSYQVAIDLAKSQHYDNSAIADVYREYGDRLYAKGDYDGAITQYLCTIGQLEPSYVIRKFLDAQRIHNLTSYIQALHEKNLATANHTTLLLNCYTKLKDVKKLDHFIMTDNGTFDVETAIKVCRQGGYFDRALFLASKHSRHDWYLKILLEDLNEYRKALDYIQTLDWEEADKNLKKYGKQLVSEIPEETTGVLMKLCTNYQPVQAFDSLTALNLNGLTISNQTTTTTTVTNVTNNNNQNNNSNNNNQNNNNNNNNNIGFKQKSAPEEFIHIFVSQADWLVKFLEYMVQQGNNESSLIYNTLLELYLRDDVNQTDDERIKRKAKAYEFLTNPKSKFDQDHALILVQVHNWKEGVLYLYEKLELFNEIIEYHMENNDYDGLIKACKRYGVKDPNLWVRALSFFSTNKQDCQDEIIEVLTNIDKENLIPPLLVIQILSQNKNTTLAVIKDYISRRLSQETQQIDKDYTQIRQYADETEKMRHEINELRTNSKIFQQTKCIACLLALDLPSVHFLCQHSFHQRCLGENERECPSCAGANKRIQEIKRSQADSANQHDQFFKLLRSSPDGFTTVSEYFGRGILN
The following text describes a protein:
Function:
Part of a complex that plays a role in tracheal liquid clearance. Probable role in sodium transport.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAFKKRRIFDLRHVQAQQMATTAIHRRSHPMHNHSHNPIQPQHRFRQIGEWFTENMRNYCQTTSLHGFSYITRQDISRHERWFWLVVVILAIITSIVLVVVSWYWSQETPTVTVIESSHFPTWNIPFPAVTICNFNKISKSKALSLLDQMQVPVGINRSELHNLFNLTLLPVDTMISNDSLQKYDRILSLNNLTLNRLTQQLSPDCIEMISSCIWKGINTRCESLFQRIDTMEGQCCTFNYFGGISNNFPEKIAYQVPKRPYRVTGCGYPTGLSVLLNPMISDYYGTFFSGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINPESTYATNDIRRMDLSLRNCLFGSEMTMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVYNNGSYKVCGVLQTNCIIHSKRLFSHALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSESTTGRLDISYFANRPTFNNATDRILLHVFFSDLMSTRYRTDIFQNWLSALASFGGLLGLIMGFSIVTAFEFIYFLTFRPVFNYINRE
The following text describes a protein:
Function:
G protein-coupled receptor that plays an important role in immune homeostasis. Acts via its natural ligand GPR15LG, a chemokine-like polypeptide strongly expressed in gastrointestinal tissues. GPR15-GPR15LG signaling axis regulates intestinal homeostasis and inflammation through the migration of immune cells (By similarity). Controls thereby the specific homing of T-cells, particularly FOXP3+ regulatory T-cells (Tregs), to the large intestine lamina propria (By similarity). Also required for skin localization of thymus-derived dendritic epidermal T-cells (By similarity). Plays an important role in mediating cytoprotective function as well as angiogenesis of thrombomodulin (By similarity). Mechanistically, preferentially signals through the Gi/o pathway to inhibit adenylate cyclase activity and activate a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDPEETSVYLDYYYATSPNPDIRETHSHVPYTSVFLPVFYTAVFLTGVLGNLVLMGALHFKPGSRRLIDIFIINLAASDFIFLVTLPLWVDKEASLGLWRTGSFLCKGSSYMISVNMHCSVFLLTCMSVDRYLAIVCPVVSRKFRRTDCAYVVCASIWFISCLLGLPTLLSRELTLIDDKPYCAEKKATPLKLIWSLVALIFTFFVPLLNIVTCYCCIARKLCAHYQQSGRHNKKLKKSIKIILIVVAAFLVSWLPFNTFKLLAIVSGLQERYFPSAMLQLGMEVSGPLAFANSCVNPFIYYIFDSYIRRAIVHCLCPCLKNYDFGSSTETSDSHLTKALSTFIHAEDFTRRRKRSVSL
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MASFQWFFFLILFLYFMSFVEQGNARFHRVFHRKKQIVNLPTVYVDPSGHGNFTTIQSAIDSVPQYNKNWICIYIKAGKYREQVRIPREKPYIYLKGEGKRKTNVTWDGHNSIASDATFISEADYTIAKSITFINSYNFPPEGNVNPMQAAVAAMISGDKSTFYRCGFLGFQDTLWDVQGRHYFKLCTIVGAVDFIFGAGQSIYERCTISTNAGGLDGLIGYITAQGRISPNDESGFVFKDSAVFGTGLTFLGRPWRDYARVLFYNTTMTNIIVPEGWAAWSFVGRE
The following text describes a protein:
Function:
Acts as a spatially regulated molecular switch, capable of either inhibiting or activating the ability of DnaA to initiate DNA replication. Monomeric ADP-Soj inhibits oligomerization of DnaA on single-stranded (ss)- or double-stranded (ds)DNA, thus inhibiting DNA replication initiation; does not disassemble premade DnaA-DNA filaments. Decreases the residence time of DnaA on the chromosome at its binding sites (oriC, replication forks and (probably) promoter-binding sites). Soj forms nucleoprotein filaments in an ATP- and DNA-dependent manner (By similarity). Inhibits the initiation of sporulation, Spo0J antagonizes this inhibition. Soj ultimately inhibits the activation (phosphorylation) of Spo0A.
Subcellular Localization:
Cytoplasm. Note=Most protein localizes to the cell septa, with faint cytoplasmic foci also seen; requires Spo0J for correct localization, in an spo0J deletion only associates with the nucleoid, requires minD for association with the septa and foci formation.
Sequence:
MGKIIAITNQKGGVGKTTTSVNLGACLAYIGKRVLLVDIDPQGNATSGLGIEKADVEQCVYDILVDDADVIDIIKATTVENLDVIPATIQLAGAEIELVPTISREVRLKRALEAVKQNYDYIIIDCPPSLGLLTINALTASDSVVIPVQCEYYALEGLSQLLNTVRLVQKHLNTDLMIEGVLLTMLDARTNLGIQVIEEVKKYFRDKVYKTVIPRNVRLSEAPSHGKPIILYDPRSRGAEVYLDLAKEVAANG
The following text describes a protein:
Function:
Component of the Bil (bacterial ISG15-like) antiviral defense system, composed of BilA, BilB, BilC and BilD. The Bil system specifically conjugates a ubiquitin-like moiety (bilA) to the bacteriophage central tail fiber (CTF, or tip attachment protein J) via reactions involving E1 (bilD) and E2 (bilB). Modifies CTF of phage SECphi27 and SECphi4, which probably interferes with assembly of the phage tail. Also modifies T5 baseplate hub protein pb3 (gene D16), but not gp27 of phage T6 (Bil defends against T6). BilB probably accepts ubiquitin from the BilA-BilD (E1) complex and catalyzes its covalent attachment to target protein (CTF) (Probable). Bil-encoding bacteria produce mostly defective phage SECphi27, many of which have phage assembly defects, including no tails. SECphi27 phage progeny produced in E.coli with the Bil system inject less DNA into naive host cells, maybe because the phage are less able to adsorb and inject their DNA into host cells; Expression of the Bil system in E.coli (strain MG1655) confers about 100-fold resistance to phage SECphi27, SECphi18, SECphi6, SECphi4 and T5, but not to SECphi17. When cells expressing the Bil system are infected by phage SECphi27 at low multiplicity of infection (0.03 MOI) the culture survives, at 3.0 MOI the culture collapses at the same time as cells without the Bil system.
Sequence:
MISAPSPDHLLLEQDLATPEIRCGEIEERWRHIRTSWPHVFFAVSAPQRPNGPKEFGFRFEYTGYRQTPVTAQLWDLEADAPLPHAKWPTGTYVVPSVFRKDWQQGNCLYIPCDRISIQGHTAWLNDHPSRLWQPARGIICYLEQLYELFNQGDYTGLVSA
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilization of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MSGTNNVAQARKLVEQLRIEAGIERIKVSKASSDLMGYCEQHARNDPLLVGVPASENPFKDKKPCIIL
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MQVVSRRLVQRPLVGGASIYSSSSLRSLYGVSNHLNGTDNCRYSSSLATKGVGHLARKGTGGRSSVSGIVATVFGATGFLGRYLVQQLAKMGSQVLVPFRGSEDSPRHLKLMGDLGQVVPMKFDPRDEDSIKAVMAKANVVINLIGREYETRNFSFEDANHHIAEKLALVAKEHGGIMRYIQVSCLGASVSSPSRMLRAKAAAEEAVLNALPEATIMRPATMIGTEDRILNPWSMFVKKYGFLPLIGGGTTKFQPVYVVDVAAAIVAALKDDGSSMGKTYELGGPDVFTTHELAEIMYDMIREWPRYVKLPFPIAKAMAAPRDFMVNKVPFPLPSPQIFNLDQINALTTDTLVSDNALKFQDLDLVPHKLKGYPVEFLIQYRKGGPNFGSTVSEKIPTDFYP
The following text describes a protein:
Function:
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells.
Subcellular Localization:
Cytoplasm.
Sequence:
MVKDILAPGLRVVFCGINPGLSSANTGFPFAHPANRFWKVIHLAGFTDRQLKPEEAEKLLDFRCGVTKLVDRPTVQATEVKLHELRSGGRNLIEKIEDYQPAALAVLGKQAFEQGFSQRGIAWGKQKIAIGATMVWVLPNPSGLNRIKTEKLVEAYRELDQALIMRGL
The following text describes a protein:
Function:
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDNWNSVRNVSSDRQTSKTSENPPHTSNEYSGKPEFINLSPDLEENLDEKLMSAFPGLEPHVFQHSQSPLSHKDASLLATMPSVASSNPSLISSGSSQTGSPSQSLSSNKEPSSPGISPSNDSQSQNTNHTSISANPYVNNPSHTSRNPDSGSSLNTASHEVPSSKSDVNVQMLARLKSKSRQKISSSDPLEDLRLTLTECLNPINIVQAPKECAAILVNLMSNITQDDQKLVFLDLLKSKVGNSIYSQLVDGGRKLFLPKLRNWFVSAIRSKHDELIHLILLVLANLPLTTEKLAEVKFGKPILIVKKKSTNSVIRQLAENLSELAEKSFTIEQNRENEKSSTKNDSTVSSSAVVMAPAGPAMAPSASNKPSASSTTKSSNSKSKKKVTSISGTSFFKNLASSTKPTSASSSTKAPLTKQQTNPSTPLSSIMAGLKGREKEKDKDSGISSENVSNNREELPSFRKRSSSSRQSEEIASLQAENAVFSSDPASNDEKTGNKKRKKKSVSWKPDNDLVQVKFIESLNEEGAASVKTPHIYGNARDMDRQEARVAFGSHVEDDVENEIIWYKPVPIKFEISKDEIHPRGYKCGGNERNLTPEATSEIEREKNESKDISTFNIILDLPVIREFDDSRPPAHIKLVSSDTQATTELGFNGLVQQVSENNTNAYSATSNSQLSSIFSNLSSSISDASSNVLQNPSLSIPNYSNAI
The following text describes a protein:
Function:
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
Sequence:
MQLLKDKFGRVHDYIRISVTDRCNLRCVYCMPEEGLTFLPHEKVLSKDEIVSFMELMVKFGIKKVRITGGEPLLRTDIVEIVRGLGAIPEIEDISITTNAMYLAKKAEALKEAGLTRVNISLDSLHADRFKAITRGGRLQKVLDGIQKAEEVGLFPIKLNVVLIKGQNDDEITDFLRFTKDKDINIRFIEYMPIGHAGTSWKEKYLPLDTIFEACNEAGYEYEPVDSIRGNGPSENFRIKGAKGTFGVIHPVSAHFCDSCNRLRLTADGYIKACLYWDEEMNIRPFIQDPVKLMQLVQKAIDNKPENHEMALKLQDEVQSNKPTWRRMSQIGG
The following text describes a protein:
Function:
Binds to SIN3.
Miscellaneous:
MISCELLANEOUS: Present with 98 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSINHEIYYILVFEHRSVAIKLIIVVIVLLQFFLARSRQIDRTWAHTNRKERFREMTAIGNTDDALDTSTAASKENGKGRLRVQKACELCKKRKVKCDGNNPCLNCSKHQKECRYDFKATNRKRRRRQVASAVRDVSKTYAETSESFPRDLLSKSNIIINAPSDGVSSSASNSPNPNSHYHHISSTLPFMSGRPNHTFHSGSNLNGENNNNSFPEDHMAKLLLQLSSKLGNTTKESSIRTTRTNASDVNANPTVVNMKNSQEDCDTNHRSAICDSAEALHNNNINSKENKIINSQITNTVNDHFESPWQTFSLDKYRFHRRYQNILPYYLGVSILKDLSPQTIEYAKLKRPRVQNYGWNLSGGHYLKYKGDFRSQEKNIRHESKFFDFDDPVHLSLINKLLRYYFDEINPVFSIIHEATFWQQYNNKFLRQGKQNNSSANLFTSMLYLILSTTLRFREGHLDGQKGQGTYSNTSLNITFEEKSILIKKPSIEENLFKYAYLIINTLTFEWESFELIQSWLLITFYFRTCYRQTACWNALSQAVNMCNGMSLYLNKFPEIHSTYDESKAWHCFWCCFIMDKLISFQMGRFYQLSLPASEMCEQMNLVKSKKFLQEEDDWFHEETFQMLDLSIIVTQFLKRDAQDLNLNETVQLRSQLGQWYDTFIVGSQTNAYDDNYRYFYQVQPFMTYLDIRLTFEVRQLFCLIAPSSTANNKSLEYVVDTELLISHCQMAIENLAEITRSNLFFVPWWLNLSQLFTVNLICIIYLHAGIAVTQNKAIMQSCQEIWRTLECSKPKNRPSMLPECLWCLKMLNHMFCIRLRDSALQLEATLGTDHGDDTPNRNKFEQFKKVGDNDADVEVDAGEREENADERQENPHNNSKRVPLATRSHNTTNFDGSIAISPESAVANLGTDTGLPSDVLDTVSKIGNSPNVFDDDLFSNLLWFDQNFA
The following text describes a protein:
Function:
Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDGLMWATRILCLLSLCGVTLGHLHLECDFITQLRDDELACLQAAEGTNNTSLGCPGTWDGLLCWPPTGSGQWVSLPCPEFFSHFGSDTGFVKRDCTITGWSNPFPPYPVACPVPLELLTKEKSYFSTVKIIYTTGHSISIVALCVAIAILVALRRLHCPRNYIHTQLFATFILKASAVFLKDAAIFQGDSTDHCSMSTVLCKVSVAISHLATMTNFSWLLAEAVYLSCLLASTSPRSKPAFWWLVLAGWGLPVLCTGTWVGCKLAFEDTECWDLDNSSPCWWIIKGPIVLSVGVNFGLFLNIICILLRKLEPAQGGLHTRAQYWRLSKSTLLLIPLFGIHYIIFNFLPDSAGLDIRVPLELGLGSFQGFIVAVLYCFLNQEVRTEISRKWYGHDPELLPARRTCTEWTTPPRSRLKVLTSEC
The following text describes a protein:
Function:
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.
Sequence:
MMLNRLETGSLASAFRGSREGFVVSRGRSPGRSQSIQVRASSGGDPAGWLQTASKQLGKLSSFGEKRKTATTTSTQGSSGDNVQYTATATIMKKLKLLDLIDRVADIQDDTSEIVGGKRVTVQLVSKDVDPKTGESMKSSEVIFPNWAGLEGPAASNIDFVLEFTVPKSFGVPGAILVKNAHPNEFLLVSFELELHDKSKAHYVTNSWVYNTEKTGARIFFQNTAYLPDETPASLKALRDQELINLRGDGTGERQIGDRIYDYQIYNDLGNIEKSEELERPNLGGNDMYHFPRRMRTGRRNTTVEAKKFPGMVYETRESKGDFYIPRDEAFERAKMSDFLADGFRSIGHSVSSKVTGFVTRKQEFDTVEEIKKLYAKKGEKVGGINNVLPDKEDIPEQEQHPLVFFQEVMRPDGKMEHPLLYPLPRLLQADDTSWRSNDEFAREFLAGLNPVMITRVKEFPIRSSLDPAEFGDPTSAITKDHIEGSLEGLSVEEAVTSNRLFVVDYHDAFLPFVAKINAQQNSATYATRTLLFLSKDGILKLLAIELALPPKTVGEERITRVLTTRKDDQLWKVNWEWELAKAHVSNNDITAHQVFSHFSRCHAVTEAVIICSNRNLSKLHPLMQLLAPHFKSTLEINRQARATLIAAGGSIETHFTTRAYSLEMAAVNYKDTWTFESQALPTDLVARGMAVPDPDSPHGVRLVVEDYPYAADGLELWGALKAWHKEYVDIYYKDDAAVLQDSELMTWWTEMREKAHEDKKDSHGWPELNSKEALVDILTTVIWIPSCLHAAVNFGQYDYAGFMPHHPTLTRRLLPEHGNEKDKADFNKNPEKYYLTSISNIDSTTTAMSVYEVLSAHSPIEEYIGERNGNWTDNAEALAAFKRFKERVNEADAVMRARNADPKLKNRGGPVKMNYQLLRPHSKPGVTFMGVPNSITI
The following text describes a protein:
Function:
Metalloprotease.
Subcellular Localization:
Secreted.
Sequence:
MDCRSFIALSSFFLLVSTTTLRDLVRIDRETSSFLHSLQNEVEKELDREIQFEQDEKFPVINPTDPLTALNSNYSDLLFEGGRPRRQATRSLNLLWTDGVPYALDSKLSATKRRVIREAIDFWHRETCVNFRPRRKEIHHLYFVGHDEGCWSSVGRDVKQKQQWISIGEGCQIFGITSHEIGHSLGVFHQQSRPDRDNFVAIMWSRIRRKLEGNFAKVVDELFVPLARTTNTFDLPYDYGSVMHYGPTSFAKDSKTATMSAKDANYFLTMGNREGPSFFDVALVNKLYGCQNRCPPLNCENGGYVDSRNCYQCKCAPVFTGTYCELPFFGPPLRDGQPCGGIVTVGEEWETFEKKSMKDEHCIFHFEAPPGKSVQFELLKVEGLCNYGCYGDRVEFRVDRERLVTGYRYCCPLDRPRQFTSLSSSPPVIIKATKDSVAVQFLYRACSILSIMFDSEMNICYTIEKNADKNALKRKSEKSIGSCKKVEIEEYEDTDSLSSSSTSTDTATVKNSRRRKTPFIHHSFLPHSTPSEIIRIFMKSQHHSSRRERLNESHEKTLRQPSLLITDFFHIPPIYKRPHNFDKVENVSLLEDITSRLAKRRAVISSRRYHCSSLLFYRKNELIRNSYEIFRVLGSRSRAIRQNNLNHSFSPKSSNNFGQ
The following text describes a protein:
Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MLNCLVVLLLCLLANPLSGQKSLFESEIVGDENRKLNVGVNLPPKFLPGGDMDGFSLPEDTAVGTIVYRLRGEDPEGSRVAYSISGDHLSVVRNTGAVTLVKALDHEATAMIEVIITLTDEKGPTAEPNIVSIRREITVEDRNDNPPKFSESSYTFLVNETVGVNTQVFNKILISDADSGSNGEIRLTCLKQVNTALSLSLLTIKGCEKFGVRSQRIAPGKFAGILTARSGLNYEENSRFTLVLQAEDLAKEPGAALTSTATVMVEVLDVQDQPPVFLNAPYRPVIHENSPAGHSLMKVLVRDGDTGQPRDLQLDIVDDPLGYFRVSSFKMNDNIGTASIVASDNPIDREDQAILRNGGTYSFGLKAIELIDNKPIGDFTVENVTVMIIDVNDQPPVFNQAQYSIGIPENLGISFRSLPGLDMTVSDSDTGVHSQFGLELIPLRNADNIFEVHPMSATGRTPVLIKVTGADKLDYENPDRREMVVQVIARGGGRRLSSTATLTILLVDVNDNIPIFDESSYSFNVVENSAPGSLISRLSATDADSGVFGQLRYELRGFGAERFSVNSSTGDLTVGVCGLSTCLDYEDQDIFTLTYTAIDGGGKATSVPLSIKIDDINDNPPVFEQNQYRRLIQNRALDFDPQLVVKATDKDGIRKGHSPPIQDGRISYSIVAGNTADNLFNIGRDSGILDVTRPINATELGEVRFVLTVRATDSGTPPQHADTVVTITVGAVDGNDPPIFQQNQYHVNVVERATPDSFVIQLNATDPDGPSDNLRYRVVGGTAVDWFTIDEVSGIVRVARGGALQWDQEAPLLTLAVAAVDQGQPLAQSATATITIQVEDINDKSPNFDKQLFIHHVAEVTPVGTRVLALGASDPDTSSQLRFRLTDPFQIRNKGGYLRDEVESEYFSISESTGILTLTKPLDHENAAVVMFRAEVTDMNANAEYPNQTDFAEVAIYVQAHTDNGPIFSPPWSPAHPIIRAEVVEEQDPGIIFLTLQAHDPVTGLLISHFELLNKLTGELTFKRRIDYEELVNKTLQFQVQAIAGEAEDKRMSLATVKLDVLDANDNSPTFTEEEYKVKISESIHHPDVLVTVSATDKDSGKFGQILYYVSGDGADLFVIDDPTNGIVRVAPNVSLDREKQPSYTFTVIAADQPQGSEEQKRSSALVMVELIDVNDNAPAFTQPSYTAVVPENAPLDWSVSQVEALDPDEQEGGIVEYSLVNEGRLEGLLTVMPNTGSIIVKGPLTGKGRSEPYVLTVRAQDKGDSPLFSDIDINVYVGDITPNDGVPSFVKPSFDEKAFIVEEAPVGSIVFQALAIDPDDPATPNGRLTYKFLDDGTLGSDHAFFEIHPATGVVTTKARLDRETKASYTLILVARDQGTPSQQATRRLNIIVRDIDDHPPQFIRTPYDGPLQFSVLEQVDPGWCVDQLKASDPDQGENAAIEYLIIFGDDAGVFTLERNPDNLVRLLVKGTIDREVVDSYLLTIKCFKPAEKPSELRKMYNPQDTSEIQVKITVKDIDDNDPVFTQTNITTGVRLNAPLHTEVVRLEAIDPDAESGPVFYKLLNVSFIRAHHYASSGGDTQIDSSSAVSKTFDLDTSTGLLTTSQTYGLFVDGYFLLHVCAWTGEESRSDRKAFNTLKVYILRDSELMKFVFTKPPPDVKPILADFRQSVEQSLELPLTLNLYESQFYSRDGALDFSSTSSCFQLVGKDHVFDLKDTELLLNAERNQRLRSVYDKFSVANLERCVPRGTLYEINNLEIWLLVIGCLIGAMALIAALTTCCLFTR
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK
The following text describes a protein:
Function:
Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. Seems to affect the stability of sigma-S, particularly during the logarithmic growth phase.
Subcellular Localization:
Cytoplasm.
Sequence:
MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG