lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Membrane; Peripheral membrane protein.
Sequence:
MATVKFFSLSCLRNESSYGDFPSKAHYPSMPKYPKGFSVSSGEEKKAIFSVNGMSCSACAGSVEKAIKRLSGIKEAVVDVLNNKAQVIFYPTFVNEETILETIEDVGFEATLVTEETNEKTSQVCRIRVQKAQVALATEVAEIQYDPRILTHNQLLEAIEDTGFEAILISTGEDRSKILLKVDGVHTENSMSIIESSLRALPGVEDVDIDPELKKLSVSYKSDTIGPRDFIQVIESTGSGRFKATIFPEGGGKQSHRQEEIEYCRRSFLWSLVFTIPVFLTSMIFMYIPGLKDGLDIKVVNMLSIGEILRWVLSTPVQFIIGRRFYSGSYKALRHGSANMDVLIALGTNAAYFYSVYSSCYFSKLQVSDFFETSSMLISFILLGKYLEVLAKGKTSEAIAKLMNLSPETASLLQLDDEGNVVKEEEIDSQLIQKNDVIKILPGAKVACDGFVIWGQSHVNESMITGESRPLAKRKGDMVIGGTVNENGVLHIRATKVGSESALSQIVRLVESAQMAKAPVQKFADRISKYFVPLVIILSLFTWLAWILAGKYDGYPKSWIPSSMDSFQLALQFGISVMVIACPCALGLATPTAVMVGTGVGASRGVLIKGGQALEGAQKVDCIVFDKTGTLTMGKPVVVNTKLFRSMVLREFYELVAAAELNSEHPLAKAIVEYAKKFREDEENPRWPEVQDFESITGHGVKAVVHNKTLIVGNKSLMLDQGVSIPVDADELLAEAEELAQTGILVSINGELSGVVSISDPVKPGAREVISLLKSMKVESKLVTGDNWGTANAIAMEVGISDVIAEAKPEDKAEKVKELQSLGKVVAMVGDGINDSPALVAADVGMAIGAGTDIAIEAADIVLMKSNLEDVITAIDLSRKTFSRIRLNYFWAFGYNLLGIPIAAGALFPFTRFRLPPWVAGAAMAASSVSVVCSSLLLKNYKRPKNLDNLEIGGITDEMIRDTMEDVGFQANKLIEEEMHHEKSSQVCRIQVNGMTCTSCSTTLESALQVIPGVQKARVALATQEAEICYDPKIVECNQLLEAIGNTGFEGILISTGGDSSRILLKVDGVDTENCVKLIKNSLLALQGVQEIDFDIQLKKLSVSYTADVTGPRDFIRAIESTESGCFKACIFPQGREREEHRQHEIRQYYKAFIWSLVFTVPVFFTSMVFMYIPGLKDVLETKVANMLTVGQVVRWVLSTPVQFIIGRKFYVGAYISLTHGYANMDVLIALGTNAAYFYSVYSVLRAATSPTFKASDFFETSSMLISFILLGKYLEVLARGKTSEAIAKLMDLAPKTATLLTLDDKGNVVNEEEVDSRLIQKNDVIKTIPGSKVACDGLVIRGQSHINESMITGESRPVTRKTGDMVIGGTLNENGVLHIKATRVGSETALSQIVRLVESAQMAKAPVQRFADHISKYFVPIVIALSFCTWISWFLAGTFNSYPRTWIPSSMDSFELALQFGISVMVVACPCALGLATPTAVMVGTGVGASLGVLIKGGQALESAQEVNCIVFDKTGTLTIGKPMVVNTRIFKTMVSEEFYQLIAAAEVNSDHPLAKAIVEYAKKLRGSEENLAWSEASDFKSIAGHGVKAIICNKEVILGNKSLMMEQGIVVPVEAEEALAETEGQAQTGILVSIDKELIGVLSVSDPLKPEAPEVISILKSMNIESMIVTGDNWGTANAIAKQVGIERKHVVAEAKPEQKAEKVKELQDLGKVVAMVGDGVNDSPALVAADVGIAIGAGTDIAIEAADIVLMKSSLKDVITAIDLSKKTFRRIHLNYFWALGYNLLSIPIAAGVLFPSTHFRLPPWIAGAAMAASSVSVVCSSLLLKNYKKPKKLNTLDLQVINEMKMHIN
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.
Subcellular Localization:
Cytoplasm.
Domain:
The PTS EIIB type-2 domain is phosphorylated by phospho-EIIA on a cysteinyl residue. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the PTS EIIC type-2 domain.
Sequence:
MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEYKSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK
The following text describes a protein:
Function:
Component of the argonaute siRNA chaperone (ARC) complex which is required for histone H3K9 methylation, heterochromatin assembly and siRNA generation. The ARC complex contains mostly double-stranded siRNA. Inhibits the release of the siRNA passenger strand from ago1 together with arb2. Inhibits the slicer activity of ago1. Required for swi6 localization to the centromeric repeats.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Predominantly nuclear.
Sequence:
MAEGDFKNDSTGCIGDSVEFTTFKKRTGKSLGNRRKKRGLSGWEPYFQEPELTAEEKLENETLYSRNIPLTVRMERFIQRYRSRRKWSDPTRIRLFTMYLDLGGVSTGQKQFTGGTDINNDAKAREVSAQTTTDYIEYDILDEYDIDFKWVAGVFLSSHILYNAGLTKEEDLQIACQIVRNFLLSVLHNNVAPEFEDNIRDACLLAEQAETELISNKRLSTKLPGRLQRALASIHVDNYKGLWDKSQSDRTSDSSVNFIESNNTKFMPNDELFEPDGISRFSTQQARDYIQRTLGPRYLTGKVVEQEYLTVKLVSKTLLNFSNQSLCKAVFIVWDPPGSKYSQDTNKERLEVILESDLLNNTVDGTHLEGSFTFLDNGLTILDTVLAVLPTFYEEVKDE
The following text describes a protein:
Function:
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSHFFHKPENALKRARELLAIPNADAGVLKRTKHSALEILHDALIAKKNRTWQPTHEDLMILYLDICMELQMGRVAKDGLHQYRNLSIQHNPASLETIIKHFVTQAERKLAAAKKESNELNLLAAAKVDLDAAQTPEDVMLSTTTFEGSNDRTDREVVVPWLRFMWETYRTVLDILKSNSKLEPLYKATAMQAFDFCVEYQRKIEFRRVCEIMRNHLSALQKHTAAPTSQSTRQMRSWEGFTLDSVERLLEVRYRQLQVATDLELFSEAFRTIDDINNIMNLVEQTPRVDLLVTYYEKLAQIFQVSKNHLFHAYALYKWYSLRVAGLQGLAGAQALQELPVQVSVDEQKEMATRVVLAALSIPLLDFEASSSVLGDDSAAQVAESSLSAAARDKNSRMAALLGFATTPTRANLLEDIEAAGLLPKASTAATEIFQRVELQEVDPLQIVKLLQPFLTTIRADPLAKAYVDGVERLVVRRVLFQLTRVYASVTIAHLRSIFVGLDVSYEEIEALIARSRSLSTVAHASAPSLSSMYRRNVTQHGSNNAETSSNDAVSSAQTRTKIRIDHVEQCIRFTDAVDLEANATQLTLLGERLARAMSKVPAAASASIAARDEQKKKLFTATRARLQEQRSDMLIRREVIERKKEELEKLQQEKLHSLEKKRHEFAQRRAELERERLTQEARRREAEKKQKIQDEIKLKETRQMLDKLGHTDVSDLDLATIDKEKVLNEAKEKARKAKELAQQKLRENARRLDYIVRATREEEQPILQRQVSDAKAEALKRYEQESAAKLKRAKEEHEHGLKEKARLAPAIQVSAEFIEAHKARRIEQYKKASEEQKKKAMLERLSARVAHAKERYEEEQRHLREEEEEKERVRREEEAERERERQLEVEEELRRQEEEEAEELRIAEEKEHEEKAQRERDEEEKHFEQRSQGRFGSAGARGVTGGPRDSFRSRDDDRRGDDKDDGEWTHVNRGGLSSRAQTVAPEGRWERRGPPARESSSDRDGREGGGLRRAFGGERGEREGGLRRGFGGEEREGGLRRGFGGDREEREGGLRRGFGGDREEREGGLRRGFGGDREEREGGLRRGFGGDREESGSRWGNRDSVRRSGDRDGDRDSFRRGGERDGERDSVRRGGDRDGDDRFFGNSQREGSYRPPRAGDREGSSRENARAPESGRWR
The following text describes a protein:
Function:
Polyketide synthase involved in the biosynthesis of methyl-branched fatty acids such as mycolipanoic, mycolipenic (phthienoic) and mycolipodienoic acids required for the synthesis of a major class of polyacylated trehaloses. Catalyzes the elongation of CoA esters of long-chain fatty acids by incorporation of three methylmalonyl (but not malonyl) residues, to form trimethyl-branched fatty-acids.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MRTATATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSVSRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGVFVGLTHGDYELLSADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTAVHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEGCVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAAGVEASTVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHLQSASGPLGLMKTILALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSWPDNTGQPRRAAVSSYGMSGTNVHAILEQAPVSEPAASGPELTPEAGGLALFPVSATSAEQLHVTAARLADWVDQNGNAGSRVSMRDLGYTLSCRRAHRPVRTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVWVFSGQGSQWPGMGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQPTIFAVQVALAAALKSYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICRRSRLMSRIAGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVGGATQSIRDLVAAWEQQDVLAREVAVDVASHTPQVDPILDELLEVLAEVDPTAPEIPYYSATLWDPRERPSFTGEYWVENLRYTVRFAAAVQAALKDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLPFGLRGFVADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQAVHPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALAAARTTLGELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQEGEPARRASAMLHALEEMPQPPGYDTNALTAAHESSMSGEELRKMFNSLGIQYGPAFSGLVAVHTARGDVTTVLAEVALPGAIRSQQSAYASHPALLDACFQSVLVHPEVQKATVGGLMLPVGVRRLRNYHSTRSAHYCLARVTSSSRAGECEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEWERGELPEVPQIDAGSWLLLSASEADPLTAQLADALNAVGAQSTSVASASDVAQLRSLLGGRLTGVVVVTGPPTGGLTQCGRDYVSQLVGIARELAELPGEPPRLFVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETVAALVASQLQSGSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDGMRLQIRTPGDLESLEFVTFDRVAPGPGEIEVAVTASSVNFADVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRIGDHVGGMSANGCWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDDKVLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRSTEFAEQIRGDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYAVDLALLTHSHPHTVRRLLKTVYQHTVEGTLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVVLDVPRTGEGVAVVPPEQVRTSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTPSPHATRVIERLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDATLANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQGAYAAANSWLDAFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIAPAEGARAFQTLLRYGRAYSGYAPIMGTPWLTAFAQRSRFAEAFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVSDQISLLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGIRVSPTKITTVRGLAEHVCDELAAAQSAPV
The following text describes a protein:
Function:
Probable ATPase of unknown function. Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MKGHQFKSWIFELREIVREIKNAHYFLDSWTQFNSVGSFIHIFFHQERFRKLLDPRIFSILLLRNSQGSTSNRYFTIKGVVLFVVAALLYRINNRNMVESKNLYLKGLLPIPMNSIGPRNDTSEESFGSCNINRLIVSLLYLTKGKKISESCFRDPKESTWVLPITQKCIMPESNWSSRWWRNWIGKKRGFCCKISNETVAGIDISFKEKDIKYLEFLFVYYMDDPIRKGHDWELFDRLSPSKRRNIINLNSGQLFEILVKDWICYLMFAFREKIPIEVEGFCKQQGAGSTIQSNDIEHVSHLFSRNKWAISLQNCAQFHMWQFHQDLFVSWGKNPHESDFFRKISRENWIWLDNVWLVNKDRFFSKVRNVSSNIQYDSTRSSFVQVTDSSQLNGSSDQFIDPFDSISNEDSEYHYHTLINQREIQQLKERSILLDPSFIQTEGREIESDRFPKYLSGYSSMPRLFTEREKRMNNHLLPEESEEFLGNPTRAIRSFFSDRWSELHLGSNPTERSTRDQKLLKKEQDVSFVPSRRSENKEIVNIFKIITYLQNTVSIHPISSDLGCDMVPKDELDMDSSNKISFLNKNPFFDLFHLFHERKRGGYTLRHESEERFQEMADLFTLSITEPDLVYHKGFAFSIDSYGLDQRQFLKEVFNFRDESKKKSLLVLPPIFYEENESFYRRLRKIWVRISCGNYLEDQKRVVFASNNIMEAVNQYRLIRNMIQIQFQYSPYGYIRNVLNRFFLMKRPDRNFEYGIQRDLIGNDTLNHRTIMKDTINQHLSNLKKSQKKWFDPLIFLSQTERSINRDPNAYRYKWSNGSKNFQEHLEHFVSERKSRFQVVFDQLCINQYSIDWSEVIDKKDLSKSLRFFLSKLLRFFLSKLLLFLSKLLLFLSNSLPFFFVSFENIPIHRSEIHIYELKGPNDQLCNQLLESIGLQIVHLKKLKPFLLDDHNTSQKSKFLINGGTISPFLFNKIPKWMIDSFHTRKNRRKSFDNTDSAYFSIVSHDQDNWLNPVKPFQRSSLISSFSKANRLRFLNNPHHFCFYCNKRFPFYVEKARLNNSDFTFTYGQFLTILFIHNKTFSSCGGKKKHAFLERDTISPSSIESQVSNIFISNDFPQSGDERYNLYKSFHFPIRSDPLVRRAIYSIADISGTPLIEGQRVNFERTYCQTLSDMNLSDSEEKSLHQYLNFNSNMGLIHTPCSEKYLQRKKRSLCLKKCVDKGQMDRTFQRDSAFSTLSKWNLFQTYMPWFFTSTGYKYLNLIFLDTFSDLLRILSSSQKFVSIFHDIMHGLDISWRILQKKLCLPQRNLISEISSKSLHNLLLSEEMIHRNNESSLISTHLRSPNVREVLYSILFLLLVAGYIVRTHLLFVSRAYSELQTEFEKIKSLMIPSYMIELRKLLDRYPTSELNSFWLKNLFLVALEQLGDCLEEIRGSGGNMLWGGDPAYGVKSIRSKKKDLKINFIDIIDLISIIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVSGDWIDDKIESWVANSDSIDDKEREFLVQFSTLRAEKRIDQILLSLTHSDHLSKNDSGYQMIEQPGTIYLRYLVDIHKKYLMNYEFNTSCLAERRIFLAHYQTITYSQTSCGANSFHFPSHGKPFSLRLALSPSRSILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGFFIDDIDIDDSDDIDASNDIDRELDTELELLTMMNALTMDMMLEIDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESSYLALGLLVNSLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFESITMGSSARDLVALTNEALSISITQKKSIIDTNTIRSALHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLISNCPIDPISIYMKKKSCNEGDSYLYKWYFELGTSMKKFTILLYLLSCSAGSVAQDLWSLPVPDEKNRITSYGFVENDSDLVHGLLEVQGALVGSSRTEKDCSQFDNDRVTLLFRSEPRDPLYMMQDGSCSIVDQRFLYEKYESEFEEGEGEGVLDPQQIEEDLFNHIVWAPRIWRPRGFLFDCIERPNELGFPYSAGSFRGKRIIYDEKYELQENDSEFLQSGTMQYQRRDRSSKEQGFFRISQFIWDPADPLFFLFKDQPFVSVFSHREFFADEEMSKGLLTSQTDPPTSIYKRWFIKNTQEKHFELLIQRQRWLRTNSSLSNGFFRSNTRSESYQYLSNLFISNGTLLDRMTKTLLKKRWLFSDEMKIGFM
The following text describes a protein:
Function:
Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
Subcellular Localization:
Nucleus.
Domain:
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
Sequence:
MASSPGLDPHPLPMLQLQEVGSSKVSERPRSPGLLPAVYSPPLGMDSHTVCIPSPYTDSSHEYNHSHGPLTFYSPSVLSYSRPPITNSPSSLCPSLSPSAFWPSHNHPTMPSLTLHCPESIVYNEPSPHAPWLESKAHSINASSSSIIGCNKSLVKRSEEGVEDMNSSLCSSAVGKADMHFCAVCHDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMMKCGVRRERCSYRGARHRRGGLQPRDPTGRGLVRVGLGSRAQRHLHLEAPLTPLAPILQAKHVHLSAMSPEEFISRIMDAEPPEIYLMEDLKKPFTEASMMMSLTNLADKELVFMISWAKKIPGFVELSLADQINLLKCCWLEILMLGLMWRSVDHPGKLIFSPDFKLNREEGQCVEGIMEIFDMLLAGTSRFRELKLQREEYVCLKAMILLNSNLCTSSPQTAEELESRNKLLRLLDSVIDALVWAISKMGLTTQQQTLRLGHLTMLLSHIRHVSNKGMDHLSTMKRKNVVLVYDLLLEMLDANTSSGGSQPSSSPSSETYSDQHQYPQPPSHLHPGSEQTTADHAIVPPLGPTDDPILDGHLDAMPLQSSPPFQSLVVPHMDTNDYIHPEQWSLGTGDAAPSVEPTDYITTERVVMETALVTQP
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
Subcellular Localization:
Nucleus.
Sequence:
MYATNNGGTNKAPNSNATSMFDNTITVTPIKMELGQAYAKSQNSAAMQRRTPNAVVVTSSSTVSSAQQQQQQQGQQQQQTVPMASLVSNACTLVNPSMSVTVATTVASGAKEKTTKATRTQVARKPPPTIDNFWPNIVSEVHSIGQVDAKHQVLPLARIKKIMKLDENAKMIAGEAPLLFAKACEYFIQELTMHAWVHTEESRRRTLQRSDIAQAIANYDQFDFLIDIVPREEIKPSSAQKTKDGSTSSSSGMAGAASSAASTSNTATSNAAASVAGNATATGNFVASGSTVPATTAGGLKLDTTGATNAAEVLGFSTVNSDIFSAQLQQQQQQQQQHAAQQQQQQQQQQHHQAHPQQVQIIQQGAGGQQLQYFIALPSQQAAQLVQQPQPAQNHLPINILSTQQPTQQLILTAGPNGQLTATPAPQTTAQQQTALLQNLAQQQQQHQQHQQQIQLLQQVVTPTGELTNVPIAINASHLNLLQRLQMQQQQQQQQQQQQQQQQQQQVIIPTQLLTTQQLLQLGGAPTVAHQQQQQQQQHANLTQQSNASAVASGTPIFINSTMTGAQAAATQAQQQQSAQQQQAQTISTMSTDRTLTGGFR
The following text describes a protein:
Function:
Acts at least in part as component of the WASH complex which may regulate wash nucleation-promoting factor (NPF) activity and is required for its membrane targeting during endosomal sorting (By similarity). During embryogenesis, not involved in the wash-dependent developmental migration of hemocytes anteriorly from the tail.
Subcellular Localization:
Early endosome.
Sequence:
MFAEDILRDYGSFISEHDGKLKLLRDKVPNRDVSESAQCVYMSPVVEVNFMGNDSMAPDRSFEESELVANKPLTTLANLCNQCRNLSRKAKRFQLAFLFSDFRLDDTLPPHTHTSEGSAGLEGSLVRMSSSMDFFCQVYFLLNRMIVILQNLWRQIAASVSVPMDINEVHIFAVFDAMSELLEHIVVFNELANQSKISTMWALYKKWLMNLSNSQSANLELNGLSTSLMDIENLITKDFFRILLDNLMELKKQFGLNSVSPITQHSNAYIRRQLLDVDANPSNELKNYEDPKHIIRLTTFVVVVHELGIQMEGKLVKNVIDLVARHKQVPLNRSVFWSPSGFLSLHAKTLMKSSARSQDGQGPKVHSTVLEKFRLSDQRTCRQLGVQLSLWSIQMQRVFDVGVFGHLKTFLQLILNGHSYADQVNLLAVALINRHVALMTPMTRNDWIVVSRLLQYLKVIQKTFESNQINFVRFISSLIQWQKQKVIHLLHTTKKKIVVLKLLQRKINFLATIKLAEKSIMGFPSKQRLTFVNLALGEFLDNRLLPADNQKLIKSILHRVNSISDIMRNIGGQLNTSESSSLVYNHWFLDTSVLKEYTELQRNPYSLQNLVSVSHHLDKIMAMFRGSRCPKQSANDLIIEFLSNHLEFFLRVEALSHLFQSQDQPFQQSALDYRLCINAVAVENDGDYNIIKDHLENYFTATFYNLTTIAPHDWKSYEKMRHLANKVLQLQPIDDHLPNQIIDQGIDVLQIMRNIHTFASSYAYNMNLQVFVETNSRSKHLDIIGTRHVANSVQTHGTGIINTTVNFIYQFLRQKFYTFSTFLHDEQIKSRLLKELRFHTEHKHSKSYQSYPYERADSFLKKIRRLGCSSNGETYMDLFRKVITQVGNAVGYVRLLQAGSKNANFRNRSYKTRFDSNFSCGGSKVHEATEGSIREYEKSLGHMKECYSDSTNYFKLLLQGFQPFLCNPHNHHLRTFYLITPALIMNYIDYRVKQKLKIYKKDQTKISLFEDGFAIGLVYILNMLNQQTEFHELGWSQTITQHLNAERSKVRDILAGQQRTAPEQLDEKLHQTVAITERHVNAYEHEYNLLYATLSSSEIFFQ
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MRPSTVVAALCGLLFSSSLVCADSSTSSRVALPADFKPQQVFKNVNLVRNTNLEKGYVRETVNVIVENVDKQPQSDYYIPFPSDVFGKVGGLEVRDKKTPGKGRFAVEALEVESPSDYQYFVVHFPEPLAPSSQITLGISYFILNSLTPRPAAIGQADKQYLTYSFSAYTPSAYQTVTQKTKIKFPNTNVPDYTTTSGLKSGSDPERQGTTYTYGPYDTATVAAGTTYPITVRYEFTKPVITASLLERDLEVSHWGGNLATEERYWLRNNASVLSKQFSRVEWTLTSYQQLPSSAVRELKYPLKPGSVDPYFVDDIGNVSTSRYRPGQPPKREGSLELRPRFPIFGGWNYSFRIGWNDELSTYLRKAATGADSYVLKVPFIEGFKVPEGAQYEKVVVRVILPEGARNVQYQVLEGASSNGLPSSSQIQSHISKQKTYMDTLGRTVLTLTVENLSDEARDSQIVVTYDHSFWDGLRKPFTITAGMLAVFVTAWLIGNLDVSIKKR
The following text describes a protein:
Function:
Serine/threonine-protein kinase which, in association with cye-1, regulates proliferation, quiescent state and cell fate during the development of several cell lineages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. Phosphorylation and inhibition of the translational repressor gld-1 by the cdk-2/cye-1 complex regulates the pool of germline stem cells and the size of the mitotic zone in the gonads by preventing entry into meiosis.
Sequence:
MSREIRSLESIISDARENTHEKMLIRKQRDMTTDIAPERDLQGRFCSLRRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVTLFDIIYANSKLYMVFEFIDRDLKNLLEMLEPTNSVLPPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNFSFPSRNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFEIVGTPNIKSWPGVDSFPHYKAVFPQWPVNLKKLEETSCLTGNGLDVLREILRYPPERRLTAKGALSHRYFLQNGFTQNRPSVTDLMKDIRAQNRTPPLLNNHQEKSIF
The following text describes a protein:
Function:
Potential cofactor involved in sensory organ development. Despite its interaction with the Polycomb group protein Asx, it does not regulate the expression of homeotic genes.
Subcellular Localization:
Nucleus. Cytoplasm. Chromosome. Note=In embryos, it is predominantly cytoplasmic. In third instar larvae, it is predominantly nuclear or cytoplasmic depending on tissues. Colocalizes with Asx on many binding sites on polytene chromosomes, but does not bind to homeotic genes loci.
Sequence:
MDNIVYDFAKITFQAKDNRSPTTNSNLSWQLNQMALSDMEEMQDTSEPIAPPESDDNVSSESHDSDDVDSQLSRCEDNDDDSDCISGSSRRSSTFGARAGVARRRMPARVSKDNFNRICSAIMKPIKKKQRKELNTNAQTLKSIEKIYTSRRMKKFTPTNLETIFEEPSDENAADAEDDSEECSISSQVKVVKVWGRKLRRAISFSDGLNKNKILSKRRRQKVKKTFGKRFALKKISMTEFHDRLNKSFDSAMLEGDDAEAGGSAEAVNIPKTSMTMEDIQLPTMSSQHQFLMQPAGFE
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
Sequence:
MKVCSVEEIRELDSLASEKYGIDQEILMENAGLAVTYLIEREFGVEGKKFSVFAGPGNNGGDAFVVARQLHSRGGIVRVLLLSDPSKYKGPALSNYKRIEGLIEIIGADDIKGAVEWADAIVDGIFGTGLSKDVEGIFKEAIESINSSGKPVFSIDIPSGINGDDAMPRGVAVRATYTVTFGLPKYGNILYPGFSYCGRLLVSPISYPPEECSKIMVELNDPIELPERVRWGHKGSFGKFLAVSGSRNYYGAPYFTALSFLKAGGGYSRLAAPKSIIPFIASKASEVVYIPLEENDQGSISLNNFDLIVRMAEEQDVVALGPGVSTNEETQELILKLIEAIDKPIIIDGDGLTALSRNIEVMRGRKETILTPHLGEMSRLTRIPVAEIERRKIEMARSFASQNNCYLVLKGAHSIIAFPDGRCFINMTGNPGMATAGSGDVLTGTIAAMKGIGLSIEDSVRMGVFVHGLAGDLAAEEKGEDGITATDILEKLPLAMKLLRSDIDLLRRRYSLEVI
The following text describes a protein:
Function:
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Subcellular Localization:
Nucleus.
Sequence:
MAGSVGLALCGQTLVVRGGSRFLATSIASSDDDSLFIYDCSAAEKKSQENKGEDAPLDQGSGVILASTFSKSGSYFALTDDSKRLILFRTKPWQCLSVRTVARRCTALTFIASEEKVLVADKSGDVYSFSVLEPHGCGRLELGHLSMLLDVAVSADDRFILTADRDEKIRVSWAAAPHSIESFCLGHTEFVSRIFVVPTQPGLLLSSSGDGTLRLWEYRSGRQLHCCHLASLQELVDPQAPQRFAASRIAFWCQENCVALLCDGTPVVYIFQLDARRQQLVYRQQLAFQHQVWDMAFEETQGLWVLQDCQEAPLVLYRPMGDQWQSVPESAVLKKVSGVLRGNWAMLEGSAGADASFSSLYKATFDNMTSYLKKKEERLQQQLEKKQRRRSPPPGPNGHAKKMRPGEATLSC
The following text describes a protein:
Function:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Miscellaneous:
MISCELLANEOUS: Present with 5710 molecules/cell in log phase SD medium.
Sequence:
MSRDAPIKADKDYSQILKEEFPKIDSLAQNDCNSALDQLLVLEKKTRQASDLASSKEVLAKIVDLLASRNKWDDLNEQLTLLSKKHGQLKLSIQYMIQKVMEYLKSSKSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEIKKEEGKIDEAADILCELQVETYGSMEMSEKIQFILEQMELSILKGDYSQATVLSRKILKKTFKNPKYESLKLEYYNLLVKISLHKREYLEVAQYLQEIYQTDAIKSDEAKWKPVLSHIVYFLVLSPYGNLQNDLIHKIQNDNNLKKLESQESLVKLFTTNELMRWPIVQKTYEPVLNEDDLAFGGEANKHHWEDLQKRVIEHNLRVISEYYSRITLLRLNELLDLTESQTETYISDLVNQGIIYAKVNRPAKIVNFEKPKNSSQLLNEWSHNVDELLEHIETIGHLITKEEIMHGLQAK
The following text describes a protein:
Function:
Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
Subcellular Localization:
Endomembrane system; Peripheral membrane protein. Membrane, coated pit.
Sequence:
MSSGSHLSKELHDLVKSIGETRSKQEEDKIIIKEVQQLKTKLNEKNMPPKKVKEMLIRAIYIEMLGHDASFVHINAIHLTQLGYLCCSLFLDNDSELLILLVATLQKDLASTNVHVVVNALTAVGKLISKTFVNALTEPVLKLLTHNTDIVRKKALMVMQIIRQLNQDCITEQDYDDRIRRGIQDKEPSVMGAAFNLNDEELKRGSVNKYKPLTGTFVSMLKQIIEHKLHKDYDYHRFPAPWLQIKLLQILTILGANDLKVSEQIYEVLGSTLRRADDTTINIGYAVTYQCVKCISGIYPQQGLLEQAANSVSRFLKSDNNNLKYLGINALTQIVSISQKYVLEHQMTIVDCLESNDDTLKKETLELLFKMTNEQNCEVIIQKLIHFLKTSSDTNFKKDLFVKVSLLNEKHAPTQEWFIKTANTLFEFGSEFIDNDVRNNFFKLLIDNFNDIGTEFGMFITEIYSDLLKNDLQDNILKIVCWVIGEIGSQIYDQDPNKLNELTQLVILKLDSQLESETTISWILTCLAKLQSARAFQMFDQTRAIFQKYMQSKNLDCQQRAIDFYTLAKFNAALKGSKDTTVDPKMSFLDAYVQQERQRGAQPYNPSLQVKAAALGSAAEVSSLNFGPYNDNKYGGTKTSTFGAGAEENKTTNQNPSAPTIAGPWDDTGYNQKQPPAPKPVITTPMAIGSTTGIGSSGTGQTTSKTTMQAMGSGQMGVNTNQTQNTYIPPVRPLPPKEDPNLKEKQKLANQLFAPISQTQQQPQQTQKKGISAVATQKPMNANPNPTQAPQQKPPAQVQNLLDIDDPLPSKQPITGVPQVYVQQPQIITQKPIVPQQQQPQQQWAQPSPIQTQPIPQQQTRSYIPANINVDQYEQLWERYQNVKEVTLQSRIKSEQDFKRMIQTININVIEVIEQEIICAGANAENKSCVLIYGCYNSNGSLDLKINGTDPKDAEYILAIIKRQFC
The following text describes a protein:
Function:
Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose.
Sequence:
MVSVTRSVFGDLPLGAGTMEKFQLQADQLGVEIISSGCTITALEVKDRQGRASDVVLGFAELEGYLQKHPYFGAVVGRVAKQIYKLANSLHRGVRGFDKVLWTPWVLSNGIKFSRVSPDGELKVWVTYTLDGRELMVNSQAQASRTAPVNLTSHSYFNLVGQGSPNIYDHEVTIEADAFLPADENLIPTGEVAPMQGAAFDLRKPAELGKHLQEFHINGFDHTFRLKGSKEKQFRVRVHHAGSGRVLEVYTTQPGIQFYTGNFLGGTLKGQTGAVCPKHSGFCLETQNWPDTVNQPHFPSVSSNTPLAHSTWW
The following text describes a protein:
Function:
May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
Subcellular Localization:
Cytoplasm.
Sequence:
MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAPARKGRQAPGRHRQ
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MSSRNDDIGIREGEKEEVLQVVEDVDTFLRSGGDHVPDCVHVLPKLLERIVDKYNDGRKKLGEEPEDDKSFLNVVERIFKLSTCDTCDIALDQTSSVLEKAMSLLEKDLCSLLEEPKQKAPKKSFSFGSRSDLSLIPSKSPFLEQDQDNHDFPFNFSSQKISILNKITTTMITTGYQIECCMTFANFRRSAFTTALQRFGHRNMKMEDVYKMPWESLEGEIATWNQVVWHCTTVLFNAEQRLYDSIFPNQPSISQKLFGDLARYVIIRLLNFAQGAVLTKWSAEKLFKFLDMYETLREDIVGGSYLESCAKELAYETSTTKDMIIEAIVAMFCDLKTSIKNDNERIPVPNGAVHPLTRYVMNYLKYACEYKDTLEQVFTQGQGANIEGIEIQNHKSIHEEVEDVGMPKNSPFALQLITIMDLLDANLERKSKLYRDLALHYFFLMNNKRYIVQKVKGCVELHELMGDNWCRRRQSGLRLYHKCYQRETWSKILQCLKPEGLQGTRNKVSKQLVKERFKCFNSMFEEIHKTQCTWMVSDEQLQSELRVSISTLVIPAYRSFVGRFKQHLESTRHIDKYIKYHPEDIELLIDDLFGGNATSMTRRRT