lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPSKTKSRTSASAATEKPIVATASSSQIGVSNSNLDSEQVLKAFRALSAHVARRNASSATGSSLPLDGPSGALRDASNTVYLQLTLSTLSPTSHIKPVRINLPHALHTPGEVSTCLLVKDPQREYKDRLVAEKIRCISRVVGVTKLKGKFKPYDARRALVQDHDIFLADSRIVPNLANLCGKVFFDARKNPITVNLTKKSEALKKELESAIQATTFLQNKGSCSTIKIGYMHKHSPEQLTQNLMAAMPAVLSRVKGGWENVNNVDVKTGNSAALPVWNKKLGVKTHVTPSNERLVDETSQPSIPAEHKHDLSAETPVKKSNSLVNKGQHTWPPTSSPSPRKTRGAAAAAAAAAAAKANLTIANDAVATPTKSAKSTPKKPTSSVGRSARKPK
The following text describes a protein:
Function:
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation.
Subcellular Localization:
Membrane; Lipid-anchor.
Sequence:
MPSPTPSSGGGPRSDVGRWGGNPWQPPTTPSPEPEPEPDRRSRRGGRSFWARCCGCCSCRNTEDDDWGPERHGDRGGRGSGSRNRRPDSRGSDSRQPGSRDSRRPGSRDSRRPGSRDSRRPGSRGSAVNAAGDGTIREGMLVVTGVDLLSSRSDQNRREHHTDEFEYDELILRRGQPFQMVLFLSRPYESSDHVTLELCIGNNPEVGKGTHVIIPVGKGGSGGWKAQVTKSSGQNLNLRVHTSPNAIIGKFQFTIRTRCEAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVSVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVEILLSYLRTGNSVPFGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVQSIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGSLIITKAIGSNMREDITHTYKHPEGSEAERKAVETAAAHGSKPNVYATRDSAEDVAVQVEAQDAVMGQDLMVSVVLTNRGSSLRTVKLHLYLSVTFYTGVAGSVFKESKKEVVLAPGASERVTMPVAYKEYRVHLVDQGAMLLNISGHVKENGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQTFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPASGGGAFSDIRGSGRSGETIPMASRGGA
The following text describes a protein:
Function:
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
Sequence:
MWRRVALLSSSISSSFLAQTASRLNTWESLTTGIAQQAKGVIAPKEKTPFITFVLGGPGSGKGTQCIKIVETFGFAHLSAGDLLRREIASKSADGAMILNTIKEGKIVPSQVTVKLIQKEMELSDNHKFLIDGFPRTEENRVSFEQILSEWQSQIGVEPNVVLFFDCPEEEMVKRVLNRNEGRVDDNLETIKKRLTVFQALSLPVINYYSEKGKLYTIKAIGTEDEIFEQVRPIFAAFEVCSQTVG
The following text describes a protein:
Function:
Involved in the asymmetric conversion of racemic 5-substituted hydantoins to the corresponding L-amino acids. HyuA and HyuB are both required for the conversion of D- and L-5-substituted hydantoins to corresponding N-carbamoyl-D- and N-carbamoyl-L-amino acids, respectively.
Sequence:
MKLFGVDVGGTFTDIIFSDTETRVTAIHKVPTTLDDPSTGVVQGILELCDRQYIDRTAIDHVFHGTTIATNAILEYDGAKTGMITTEGYRDIIHIGRHQRPQNYSIMQEIPWQDRPLVQRRHRLAIAERMGPVKGQVITPVQEDQVRGAVATLKERGVDSIIVNFLFSYTNPEHEQRVKEIIEEEYPEAFVTISSEVSPQFREFERFTTASINGFVGPKVKNYIQNLEQSLKDSGISAELHIMCSNGGVATPKTVSEKPVNTLLSGPAAGILGGAWAGELTNRQKLITFDVGGTSADIGIITDSGYGESSARDTWIAGYPVMVPMIDIHTIGAGGGSIAHIDEGGAFKVGPRSAGSRPGPACYGHGGLKPTVSDANVVLGRIDEHNFLGGEMKIYTNAAYKVIDELAGQLDLSRERTAEGVLQIMNNNMANAIREKTIQKGEDPREFSLVAFGGAGPLHAVEVAQILNIPEVIIPLYPGINSATGLLTTDLKYDVIKTEFMMSTNMDFSGLNEDLAGLETQLINQLKEDGVSKQDIRILRSADCRYAGQGYELRVDLPDVFLDEETIVDALNNFHESHKAEYGHNFTDSPIEFVNIRVTGTGYMPKIEKQAIHHEYQLEDALLKTGDATFNIDGSLVKVEINFYQREKIPVGAEFNGPCIVLQKDTTTVIPPNCTAYIEEYGNMIIKVGV
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Involved in regulation of synaptic microtubule formation, and also regulation of synaptic growth and glutamate receptor trafficking. Does not appear to be required for basal neurotransmission.
Sequence:
MDAPPPTKPPRGVKYGKDESAGCGFLVNVIKSLGFSETTEERQKEKQKIEAEFKRSDLRLNELVSRHDQQLTQVLPLFSQVSSEVTASRERIHAVKENLGVCKRLLQCRRDELRKMWMDAVQHKYVLEMLEQIQELRKVPQRVVGYTAKRQYLHASKALTDALTTLNGPLQAVEGLSDLRTDLQTRRQQLYQRLHEELVTQVYTNSANEALSSFQRTNSSRLNSSFTRGIGARRSTDRIEANARVRKALAEMAQSFDLDKAEVIEDADLIYPELSMSYFVAIIVESFGMLHKVPDSLETLRVQIQTELLNVVRHTTHQLSVSGATADTNPLLSLLEVIFKQFKAIAKTHSLLLKNYLSVGQKYSVVGPQPYDLTDFWAQAQSVLQLLLTDYLDIQNAAADESAQTGFSEPTSNINSYFLRRKVPSTKRSMFKFDKSSHVGTSNNSDAFKEHRRNASDASVDDNLAGQLGGSGKGSTSGLFPHEKKQREKILICTPDQSIITKVYLPLMGYIKEIENFMKCKPGQPCSLHDFLDNYIKDTFLTKGHNRNLQLTIESLSKNQDAWRTIISPEEIKALNLSRPLLQSTVMVERRLMETKNLIQDLPCYSEDLLKMVCALLKAYREICQAAYRGIVQPDSEDKRIYSVAWLKDEDISRFLKTLPNWTDLKTYSQKSRHNRKLHRGSFEPSEEESPLQVQQRNIREAEMLTSNLGEGGITQQEILVEISVLKELAILQESMEWFSCRVSEFANDLRRPLVNGLNAVPAECGADIAVKDGTIKVMTNLALEFDELANTCLLVLHLEVRVQCFHYLRSKSSVRTNSYVGSKDDILEPDRQVQVLTKRLSEMDEAFSATLHPRKTRYIFEGLAHLASRILIQASNYLEHIDQITVQRMCRNAIALQQTLSNITASREVALDQARHFYELLCMEPDEILNALLERGTQFSEMQLLNALQLSCKSFGITDANLLASYQQKLSDILGAKPSKGVVV
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
Sequence:
MSVTVRVPAKVNVQLAVGAARPDGFHDLANVFLAVSLYDEVTATPAADGLRVTCEGPDAGQVPLDRTNLAARAAEALAARYGRAPDVHLHIAKDIPVAGGMAGGSADGAGALLACDALWGTGASREELLEICAGLGSDVPFSLVGGAALGTGRGERLAELEVGGDFHWVFALAARGLSTPAVFREFDRLGEGLDLPEPVADQAVLDALAKGDAAALAVAVTNDLQPAALSLFPELSDTLAAGRAAGALAALVSGSGPTTAFLATDARSASDIAGVLRASGTCRDVRTAVGAAAGATVLD
The following text describes a protein:
Function:
Probable RNA binding protein. Negatively regulates myc at the protein level, via an unknown mechanism, and may therefore have a role in growth. Has no effect on myc mRNA levels.
Domain:
The HTH La-type RNA-binding and RRM domains are required for its function in negatively regulating organ and cell size.
Sequence:
MEYFLGGYVYMNGDALKIQPPVYTNVPVETAMLATNLFGATTQIAASPAAAAAAHIPLITAAAAAAAAAGAPAVAPPVAVAPVATASAAQAAVVPAQQQQQAHPHQAQILAHTHVAHQQQQQQQQQTIQQHLHQQQQQQSPHPAQHLTYGHQPALSQATAGGSGTISGGAVGPSGVVVEGQDTNEYAIMNGALGQTQDGTVVCYTTDALNNTNLVALDPQPHQIVVPVQVPVQVPVPVQLPANGSADPQQGSHNAAGGEEPNIPLDKLKQMLATQLEYYFSRENLANDTYLLSQMDSDQYVPIYTVARFNLVRKLTNDINLITEVLRESPNVQVDDKGLRVRPNRKRCIIILREISNNTPLDDVKALFSNESCPRPISCEFAANNSWYITFESDEDAQKAYKYLREEVKEFQGKPIMARIKPKSFINRIQAVPKNGYRLTSPPTANVFDPAGAGGATVSYAAAQQPRYLYTNGAAIAAPASVQYSNPVLIPIPQNQFYPGLVAGPWPPGTVAATTAHGQNFYELGGNIFTTNPLPPQPVTAGFAQAPPPTSQAMVTPKPQGGGRYNNNHRGNPNNVGGANSGPRAESRSKPPRSTPSASHIQGGNIMPIQITAPIPGGMVSVVPTNIVQDPLQPAPLQQQPQQVIQQIQQQPSSSAQQQQAATVQMNNTTRHYPIKSNWKGGMQKNLDKSYSGGVATHHHYTTQVQALPAHSHHLQAQQQLQGQTQQQHYQLASSSAASAPQVTYVTTAPAPQQPGQHQHHLVVQQTQPQQQQQQQQVVLQQQQVQVQELQEAGDGVEHSSHAMQQVNRSSNMSASSSSSLATSMSKEPLQWQNRPRRRRRDEEGGINYSPGGRVGLYGSSPSNPHPQQHLMSSSTGSNVQSAGGTDGGGASHRGGERQSHYNTIHDVPPPQHRGNYKGNNYNPHYHAQHSSMASGSHHHHHHNALSSQQQQHHLTTGTGQQGSGHHYHHHHHHNSIGSNVGNSGGLGVSSGGSGGGGSGGGSGSNSLSGGSNERGIHHSSLGYQGHQHQHQQQQQQQQQQQQQQPAAPVQPPQFDLEDAAFPPLPATSATAPHTPQATGGASLHNSTTSSSSSTGLGQKQTLHQQQQQAPQQHQVLSSSVESAGGDEQRSSNQQGIETSNIHLANSSTANNWVENRLSDVVRTGGGGGGGGKGKARKDNRHPQGQNQPHMAPNYQQHQPRNPPVSPTPALGAEYGIQIQEGNNTKNVTKQSSSNNNSIHVIKCQTPNINASSKEEAAGAQQQQQQQLDKSNKTEDEMHPKQPSQQRLVEGYVQQQQLPLLAAHNEYSAALAAGAGACSVVEGGLTTSLAECSLGQHKKPPSVAALHAKKDANLLEKGASKHKSVATSTSTENLSAAATASKLSYAQVAQHHKAAASSDSKETGSGGSTGTLSPTGSHKMDLVFGDPAVVVAAVEKSGLATVSTEKRVAGGASPAALIGKPAGGLPATNTTQGSSAVVVSAKEKDNRPNASVRPLSKEKQQQHYGSATEHNTNANIGLGASGNRKSRANNS
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MDAYSKDMPRGVSGGDDGEKKVRRSESRTEEVDLTLGLSLGGRFGAKRRRVEGLAGSSSVAVAPPAPVGTNSSQGTGFPPNGVAVEPSALLRATATLNPFLGRAGAAGFQPSATPLISSIKQEPVEGTPRAEGRGLSSAVVPWSSLASAVMIAATLGSRGEQQGASGRPAALREMPLVWTRGLHNGMRTVGFLYQYSRVDELRIMCVCHGSFLTPAEFVEHAGGGQVANPLRSIIVKTPSWL
The following text describes a protein:
Function:
Transcription activator that binds to the DNA motif 5'-CACGTGG-3' in the promoter of iron (Fe) deficiency-inducible genes as well as of genes involved in iron homeostasis, thus contributing to basal tolerance to iron deficiency, iron uptake from soil and iron transport, particularly during seed maturation and germination. Promotes the accumulation of mugineic acid family phytosiderophores (MAs). Required for ethylene-mediated signaling during iron deficiency responses. Improves growth and yield, especially in calcareous soil with low iron availability. Promotes iron concentration in shoots and grain.
Sequence:
MGHHYQLFEDPFASSMSSLEPDIFSGAGVHHHLAPSPQWLGLGNHGIPVAPTANNGTSSGGDGDGSGSHRKISHNAYERDRRKELNELYSDLRSLLPEDDRTKKLSIPITVSRVLKYIPELQKQVEGLEKKKEELTRASCKPGVLTMRENTAPIVSATCIDDRDIMVQVSLVSTMAGDLPMSKCINVLENEGLRLISSSTSAFQNRTFYSLHLQRTQRTMSKECPAFCEELENVMKQKAGLRLHQ
The following text describes a protein:
Function:
Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of proteins beginning with Met-Asp or Met-Glu (By similarity). Required for chromosome organization and arrangement; specifically for assembly of the central region components of the synaptonemal complex onto chromosomes during meiosis and for DNA double stranded break formation and repair. Acts downstream of xnd-1 to regulate levels of histone acetylation in germ and somatic cell nuclei by controlling acetyl-CoA production through antagonizing the acetyl-CoA hydrolase activity of acer-1.
Subcellular Localization:
Cytoplasm. Nucleus. Chromosome. Note=Localizes to meiotic germline nuclei where it is first expressed in early prophase nuclei with expression increasing as nuclei progress into the pachytene stage. Expressed from interphase to prophase and at low levels from prometaphase to anaphase in mitotic nuclei. Highly expressed on autosomes during early to mid prophase.
Sequence:
MSKAELAVLERRLRPIYDSLDSQQFKKALSDCDKVLKKHPNTSAAKVLKALTLIRLEKLADATEILEALDVPGAHHDELTLQAFVHCYRDSNQHMKVVTLYERIIQVDPSEHNLTQLFMAYSREKMYKEQQKIGMRLYKDFGNAPYYFWSVMSLIMQAQENPELGKKMLLPLADKMCQTQVEKSGYTEGSSAELDLQLLILEGQEKWKECAAFLDRPQASVLPMAPYNLVEKGMDFLMKDKQYKRVDQLAMEAVTKMPDNWNLWKIITESTICQIEQCLESDNKENIELAHNFVKRLGLLIEKVQKQVGYKSRAPFIATFFAYKQIGKLTKQIPDMDDMTSIFGEQVDKMLEYAKNFYKKPVCFADLQMFFCDLTSEQKSNFLKGIDLWIGEVSAKDDVEGDESKVWAIILTERCRRALGEYEKMDAAGHRSLFQQCIAQIAAPERTEHAQGVLCNLTVSHLWDAYRKENDLTKFYEMILLLEFVAASNKTDPMCKLALIRAYSALCATGRISALVKTLDIKVIQMDTLGHLTFPVYETSGRFNLAIIQNTQLSLMYEQAEKEIQDCIAQAYRNGKFSAIPRMTAASKHMKLSAQKTACDVMNRYLSSLFVLDDVDQITVTLWGDEDPIGEKRIDWKQLIDTRDFNAIPYTETEEYEALLDDMKKRTFKELIDISELRSTLCRALGAVGRVTHENMEPRLARLQLKMTVMEFKQHLEYCCREYPSFLIPSKLAQSPAPHHLSQWVHSGGLQMVLEYLEAAVKLVDILDSGEHPEKSLVGTRTEMATKLIKLIEIPPKRKEGEKLPPFWIVDPIIKSSRALQTIAAIQVVLRLIEKVVLKLVKNVPTAVPEPVGKGKGKKDKKAAEEAMTKALDECKAVVFLEHIRAMHVELRSAGNFLHTYLGQMLALEDEYIPSNIGEDLGGAKAALEGMHNPVASRLQRSFLNTCEDMHTTIKLRF
The following text describes a protein:
Function:
Oxidoreductase involved in lignan biosynthesis. Catalyzes the stereospecific conversion of (-)-secoisolariciresinol to (-)-matairesinol via a lactol intermediate.
Sequence:
MGSTSTPDSSTNRLQDKVAIITGGAGGIGETTAKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVFGVDSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYTRTNPAFPTALKHGLA
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus. Note=Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm.
Domain:
The homeodomain differs form the typical one by having namely 4 instead of 3 extra amino acids inserted in the loop between helix 1 and helix 2.
Sequence:
MEVREKKDEKMEMTRRKSSALDHHRLPPYTYSQTANKEKPTTKRNGSDPDPDPDLDTNPISISHAPRSYARPQTTSPGKARYRECQKNHAASSGGHVVDGCGEFMSSGEEGTVESLLCAACDCHRSFHRKEIDGLFVVNFNSFGHSQRPLGSRHVSPIMMSFGGGGGCAAESSTEDLNKFHQSFSGYGVDQFHHYQPKKRFRTKFNEEQKEKMMEFAEKIGWRMTKLEDDEVNRFCREIKVKRQVFKVWMHNNKQAAKKKDL
The following text describes a protein:
Function:
May control the production of phosphatidylinositol 4-phosphate (PI4P) by the STT4 PI 4-kinase. Mediates proper localization of STT4 to the plasma membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIQFKSPGNWLFIVPWIAFIPWYGMLIAMLICWASQGHPIYWFMHSEQFPVYISDIGATNLRPLFISCAGWQGLGYVITVALEFFQRSGYLPFQLKKKDPSISDSTSYAEKLHSGKYLMPPYYTKDERNLIFAAFVLGSIGELALLFSSIFSTALYHRVHIAMVSVFVVFMFLSTCCLIAEYFLMGRHYASVHPLASPHFNPQSSEKSFNQDYNTVDELPWYKWKGHVWNKFTISATLKVIWLTLAVVWAICFGAINDRSKSACFEWLLAFWFGIIFMILSADFYLGGRYRQSRYFNHVESFSGYYKYDKALGLYHSEDVLPSDDNAGVIATETASSNIYNNSSSNESIQVVV
The following text describes a protein:
Function:
Involved in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2.
Miscellaneous:
MISCELLANEOUS: Present with 656 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAGENPKKEGVDARFAGIYSDPKFKNTKTKDHKIKLDSRFSKKDLEVQHKSKVDKYGRKIKNAQNNRELEDFDKYFEKEAENDEDSEVNAKTVVDRARGEVPDDYVSSSDEFTSSDSESSGESEVESEEENEVEIENAKPESGDISKNLAVVNLDWDHVKSEDLMITFSSFVPKGGKIERVAIYPSEFGKERMQREEVEGPPKELFQKKNKNKTSKKKKTDDSDSDMDIGIKDLYEEGDADKDVDSRALRQYQLDRLRYYYAIVYCSDTTTSKAIYDNCDGTEYESTANMFDLRYVPDGMTFDDDVRDECSILPKNYRPHQFSTDALQHSSVKLTWDETPADRVEVAKRAFTQKEIDDMDFKAYLASDSDESDGQVDEEAKNKLKSLVGDFGFNSKKETPNDEDEEVDMEITFTPALEGGNEKSSEDKEETTIEKIRRKEKERRKARKQKVKELKQQSEKDKKSKLKSVNKKHTNDEEEIEKNAKSKAELELLMDDDDDTETQGTINNKAHFNMNEILRSEKEKHKKGRYQKKERIVEDTFTPDLEDPRFKEVFEDHDFAIDPTQPEFKGTQAMSKILKERSKRVKNKKRKLGGSENNMTNNADDNEDIGNLVNKLKKKSKSSKKVKV
The following text describes a protein:
Function:
Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells.
Subcellular Localization:
Chromosome. Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MEVKGKKQFTGKSTKTAQEKNRFHKNSDSGSSKTFPRKVAKEGGPKVTSRNFEKSITKLGKKGVKQFKNKQQGDKSPKNKFQQANKFNKKRKFQPDGKSDESAAKKPKWDDFKKKKKELKQSRQLSDKTNYDIVVRAKQIWEILRRKDCDKEKRVKLMSDLQKLIQGKIKTIAFAHDSTRVIQCYIQYGNEEQRKQAFEELRDDLVELSKAKYSRNIVKKFLMYGSKPQIAEIIRSFKGHVRKMLRHAEASAIVEYAYNDKAILEQRNLLTEELYGNTFQLYKSADHPTLDKVLEVQPEKLELIMDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTYAPPKLRSEMIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISSLPSIVNDKYGRKVLLYLLSPRDPAHTVREIIEVLQKGDGNAHSKKDTEVRRRELLESISPALLSYLQEHAQEVVLDKSACVLVSDILGSATGDVQPTMNAIASLAATGLHPGGKDGELHIAEHPAGHLVLKWLIEQDKKMKENGREGCFAKTLVEHVGMKNLKSWASVNRGAIILSSLLQSCDLEVANKVKAALKSLIPTLEKTKSTSKGIEILLEKLST
The following text describes a protein:
Function:
Polymerase that creates the 3'-poly(A) tail of mRNA's.
Subcellular Localization:
Nucleus.
Sequence:
MHTVYENENLIECSNFMLNRKDSLEEFFEVSEIKEENEETYLNYNIECTLNKKIEDKKNNVTYRREIINEENIQENKKYEEGGVTEPISLNYPSEEDIKRSNDVVELLKGYNLFEEESGLKKRENVLGMINKLFHEFLIELSINQGISEEEANNISGNLYTFGSYRLGVITPNSDIDCIFLAPQNLTREIFFNEFYLKLQQDRNVKKLQALPETYTPIIQFMYDDVDIDLLLATLPYKTLKDCYYSLDNDHILKNLDEVTVRSLNGIRVADLILNSVPNKDYFRNTLRFIKLWAKSRGIYSNILGFLGGISWALLTAKICQLYPNFNVSQLICKFFKVYSIWNWKYPVLLQNIKKYNIEGLNNFPVWDPEKNIKDKLHIMPIITPAFPCMNSTHNVTYCTRNILIEEFKRAHSIIQYMEDENNIKSSIRMNKLWPNNNVNNINNSSNNVWMTILEPLDLFSTYKHFLHIQIMGINEFIYNSWKGWIESKIRLLFKKLETINELKIRPFPKFYFYKKEKSYYCSSFFIALIFFYKNPYENTFNLSYAIRDFIDIALNWPQKVKYPNAFKINIMYQKRSQVLEFLDIVTKEENQKNKQVMENNDKDETNHNQNGYRNNHKNKQFDEYDDHLFN
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MAPKKKGGGKKKKKDDGAEPPHDGSWERAVESGTWEKPVTDLPDANTWPTWGALRERVLTACREIKINNTASLRDAFANELVKLSPPELTLIDLRGSSNLHNFNLSPMTTCPKLTDLDLSECAGLDYVLLQSQTVRSVNLRKNPAITKALIHCPRLNKLSITDCPALETLMLWTDELTELDLTGCNNLSVVKLQCPNLLDSKIPPLKVAPQHVKPSHPPIASLLKENLTTAAHKAAADKEALAGVKDTSDSIIPHVFRPF
The following text describes a protein:
Function:
O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His)), acting as a capping enzyme by protecting tRNA(His) from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.
Subcellular Localization:
Cytoplasm.
Sequence:
RTNMAAPAGDGVKEECEQVIQDDPGAARFGNFINYYTFNPPENRLSLIPANLLEELGYSSDNSAPILILDVGCNSGDLSVALYRHLLGQDGSPGETQPSRELHLLGCDLDEALIQRAQQSNPFPETVSFTQLDVTQEQACRAQLGGYLGRFGRASFDLGLCLAVTMWVHLNHGDPALLALLSRLPRLCQHLLLEAQPWKCYRAAARRLRRLGRRDFEHFKELGVRGDVAGQAREHLERRCGMELVRAFGSTAWDRSLLLFRRRGAGGDSP
The following text describes a protein:
Function:
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
Subcellular Localization:
Nucleus.
Sequence:
MFLTASLSGTFRRSLGVNFVCKRGLLSTLACTPYRKRDDWLFSATRYKNTLYLCKFESESHRAWESQNPKLAKQMHFWGHKFEQYMTSRALPDTSTPLRSGDQFYVVLKGRLGSHSLLFTAEVDAIDNDVSQEPGSTAAYVEFKTARIMTHPNLERNFFG
The following text describes a protein:
Function:
Cargo receptor for the autophagic turnover of ferritin (By similarity). Acts as an adapter for delivery of ferritin to lysosomes and autophagic degradation of ferritin, a process named ferritinophagy (By similarity). Plays a role in erythropoiesis, possibly by regulating hemin-induced erythroid differentiation. Binds chromatin before initiation of DNA replication and detaches during replication (By similarity). Inhibits activation of DNA replication origins, possibly by obstructing DNA unwinding via interaction with the MCM2-7 complex (By similarity).
Subcellular Localization:
Nucleus. Chromosome. Cytoplasmic vesicle, autophagosome. Autolysosome.
Sequence:
MSPMGQREKAALRQCIQARAQLDEAIADIIKAEVQLKSNSREVKSQLHSCISRHLEILRSREVWLLEQIDLVEQLKGETLHQQLQQLHSLKGQFDLLIHQLEYSGSNSLTTQLTDCLEKLSSLNLTPEETPEMSFQADAHTLRKAITSFGTIASEQMETSESFARPWLLQDCPVFFKKQKLDPERTTPLTEWLLGNHPVCSAPVKYHFSTNPHDWLLVSKESQEEKQLPAFDFQKAWGQLHDLESWLLKEKLPIRKRTCSSSSTFSIEMIDESDFNLDDVEDEQEKASDTFEKEELNKWLVNSSLVKPNQTNPDAERFKQIFKPFYESFSSSDWLSKSDCGSCCATRTTAVEIENLGKLKCLKTPPPSTPVTTPDPMEMWLHKTIPLESTCKANETCTSYAQCVCEDNCGKEALSAWLLKKEGRDKNGVPVNKNSTSKASSHQQEQQQKVQAILEAWLHPSNSAKSPDLTSLSAWAIPHIKLADPENSVENPLQAENWLHPAIKQISSATEMPNKAESKSAKDQDGKDNVEEDKWLLRKRVSAQERLGLPIVCDLFSCMKLGGDKEKWLHQAATQI
The following text describes a protein:
Function:
Catalyzes the dehydration of D-altronate.
Miscellaneous:
MISCELLANEOUS: Last gene in the exu locus which is required for galacturonate utilization.
Sequence:
MKSFIKIHKQDNVLLALRDIQKGERLHAYGVSIEVKDDIKRGHKIALQSIKENDSIVKYGFPIGHASQDISIGEHIHVHNTKTNLSDIQLYSYTPRFDENPYSNENRTFKGFRRENGDAGVRNELWIVPTVGCVNGIAEKMLQRFVRETGDIAPFDNVLVLKHQYGCSQLGDDHENTKQILLNAIRHPNAGGVLVLGLGCENNELARMKEALQDVNLKRVKFLESQSVTDEMEAGVALLKEIHEAAKGDKREDIPLSELKIGLKCGGSDGFSGITANPLLGRFSDYLIAQGGSTVLTEVPEMFGAETILMQRAANEEVFHKIVDLINDFKQYFIKHDQPVYENPSPGNKAGGISTLEDKSLGCTQKAGISPVTDVLKYGEVLKTKGLTLLSAPGNDLIASSALAAAGCQIVLFTTGRGTPFGTFVPTVKVATNTELYEAKPHWIDFNAGLLAEDDVHEEYVLREFIHYMIEVASGQLVNHEKNDFKELAIFKSGVTL
The following text describes a protein:
Function:
Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
Subcellular Localization:
Cytoplasm.
Sequence:
MALPREADGSPGPECPSGPWSAAPDFAYGREDLVVEGVRWRRGASGELEPPAPSRFDQALGAAWGRRMEEGLFRYRLGELPTRVLPGPLGLVAQLNVERGERRRRPQDVRSVRQAFDPGQFNFNEIRPGEVLFRLSREPGREPGGGARVLVVINVSPLERGHVLFVPEPALGLPQLLLEEPLLLAAEAVLLSTHPGFRVGFNSLGGFASVNHLHLHGYYLARPLPVETAASEPLDPRGRMHLLRGGPAPGFLFFAEGPDLGPAVRGVCRVAAHLAEGEIAHNLFVTRGAPPGDPPAPGAPAGLRFVLWPRRAGFGVKEGAAFNVALCELAGHLPLKTARDFRDLTEAAAMSLIRSCLLPPDRFARLQRDLLALLD
The following text describes a protein:
Function:
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKKKKRFKQKLLIASLVIGLMAVLSGCGYSTDPITSESTGFWSHYIVFPLSWTITWFSDLFGGSYAVGIIVVTILIRLLIMPLMIKQLKSQKAMTNLQPKIKELQEKYSSKDNETKQKLQQETMRLYQENSVNPMMGCLPLLIQMPILLGFYQAISRTAEIKTDSFLWMQLGNPDPYYILPVVAALTTFLSSKISMMGQTQQNKSMAMIVYIMPVMILFMGITLPSALALYWIIGNIFTVFQTLLINNPFKNKREQEALAAAQVAEDRLKKKAANMKASKKGGKKRK
The following text describes a protein:
Function:
Catalyzes the hydrolysis of N-acetylated amino acids to acetate and free amino acids.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSKDPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEERARQLGLGCQKVEVAPGYVVTVLTWPGTNPALSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANPTDAFTVFYSERSPWWVRVTSTGRPGHGSLFIEDTAAEKLHKVVSSILAFREKEWQRLQSNPHLKEGAVTSVNLTKLEGGVAYNVVPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEFAQKWMHPQVTPTDDSNPWWAAFSRVCKDMNLSLEPEIMPAATDSRYIRAVGVPALGFSPLNRTPVLLHDHDERLHEAVFLRGVDIYTRLLPALASVPALPSES
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Involved in the regulation of flagellar motility (By similarity). Essential for male fertility, sperm head morphogenesis and sperm flagellum formation (By similarity).
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Associated with the outer doublet microtubules (OD).
Sequence:
MEYLEDNKTETFEEEDKEREEDQVLDSDEVLDSNELNDMQECLSQTDLSNIDNNRAIQQLSLGSMEFPSYTTNSEKEEMLLGLADNFWHQYTHLYPDRKPLFMCPRNECGVEKFVCTTLHPTLLPYSDLYDWDQSAKFVSEYLTMEPLNPPLELPRSLFSSTSVLQKQSGNCFDFSVLLCSLLLGAGYDAYCVSGYATREMCLMDEKRNICPLLNKVEESSWEIPQKPLKKYTVKPPRQLISKFAVQQEAKKQAKMEEALRNEQEEETRLKEDAEKPGPDNLHGLRVHCWVLVLSGKREVPENFFIDALTGKSYATISEPFLGVESVWNHEDYWVNMQDCRNGCKDMKFDLGDPVCWEYLLQGGSKPLLLIPDEEDEEELNGETIQENKTIFQMPPSWVLPIVIRPKEFETRCPQGRKILQYKKAKHEKWAPYLKRDGHVSRLTGYLDTECTQEVKIQDCFQNRKDKLDLREQNKIEQVTTEYFIPGRADSLKVHEYRSLAPETERSMMFYSEARLDGLQRRDEKPVEMTEIYQGRADFLYYRHIVFGKRPKKVAIAGGPTEANPRPILKITERFNRNKEKPANEDVAERTFLLTEDRIQLRCHRKDDHITTSYWEFLKPANLGEKDTPIVLTPETCISYQVEPSEKFSKQLYVYETLVTLQQAEQNSKDNVRKSETEVREILATRAQEEADPQLTISIYDTERNEKSKEKREAMERAIQEERQRRAVQELDYLAPFLAQLGDPEKLTLWQAQKVKEDCLSDMKQRLIEKANLIQARFEKETQELQKKQQWYHQNQMSMSKEDEEAYLDYCSEAMFRIHILETRLNRHKDLAPQKYLALEDRLNKDPRLREPFLTS