lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
[CLE22p]: Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance.
Subcellular Localization:
[CLE22p]: Secreted, extracellular space.
Sequence:
MGNYYSRRKSRKHITTVALIILLLLLFLFLYAKASSSSPNIHHHSTHGSLKKSGNLDPKLHDLDSNAASSRGSKYTNYEGGGEDVFEDGKRRVFTGPNPLHNR
The following text describes a protein:
Function:
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3' (By similarity). SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending (By similarity). Also involved in pre-mRNA splicing (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons.
Subcellular Localization:
Nucleus speckle. Cytoplasm. Nucleus. Note=Acetylation contributes to its nuclear localization and deacetylation by HDAC3 induces a cytoplasmic delocalization. Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus. Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH).
Sequence:
MEGHVKRPMNAFMVWSRGERRKLAQQNPSMQNSEISKHLGYQWKSLTEAEKRPFFQEAQRLKTLHREKYPNYKYQPHRRVKVPQRSYTLQREVASTKLYNLLQWDNNLHTIIYGQDWARAAHQSSKNQKSIYLQPVDIPTGYPLQQKQQHQQQQHVHLQQQQQQQHQFH
The following text describes a protein:
Function:
May be involved in plant defense.
Subcellular Localization:
Secreted.
Sequence:
MLVAVMIVMVIGNLLAQTAAQKIPFKECYPACLVECKAGSKFPKYLKCPFTCTKECLQQPSPPSVSSNNIDESDYFCKLGCATYHCVSLSSIQNPNVERVSACVDSCSNKCTKKN
The following text describes a protein:
Function:
Involved in rRNA-processing and ribosome biogenesis.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MRQKRAKNYKKQMQSYHLNFKFREPYQVLVDHDLIIECVEHKYDLLKGLQRTLQTKEVKPMITQHSLNKLFESNNEEAIQLGKTFERRRTLHFENSTETQEKKLKYNGSNAARKMHPSEAIYKSVVVDGSNVHRYVVATQDPSLRGRLRSIPGVPLIHMNRAIMLLEPFSPASERARQLIEASKLTSGLNAVKRKAPEGDEEQAKKRKGPKAPNPLSVKKKKVSKEDQGKRERPEEKEDDSQSVKKVRRKRAKRKDGEGGESNEGGETDEVPQLVKDSPRTGEDNETKEETPKKETNSEGKDDVPMSDE
The following text describes a protein:
Function:
Involved in protection from oxidative damage.
Miscellaneous:
MISCELLANEOUS: Present with 1560 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MFGVKDAIFKIKRSIAGTDSSDSTAYTTASESSPQLKDSHNPFRNKTTSERTIVEEGSLPPVRLNGYLPSTKNKLLTPEMCDEIRTLMPTRIQLYTEWNLLYSLEQHGSSLHSLYSNVAPDSKEFRRVGYVLVIKDRKNGIFGAYSNEAFHPNEHRQYTGNGECFLWKLDKVPDVNISEKEESEQEGKEGKEEGDKEERWRFSGYPYTGVNEFAIYCTSEFLSMGAGDGHYGLLCDDGLLHGVSNPCQTYGNEVLSKEGKKFSIVALEVWRVG
The following text describes a protein:
Function:
Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Note=Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca(2+)/calmodulin. Colocalizes with F-actin at the leading edge of migrating cells.
Sequence:
MGSQSSKAPRGDVTAEEAAGASPAKVNGQENGHVKSNGDLSPKGEGESPPVNGTEEAAGATGDAIEPAPPSQGAEAKGEVPPKETPKKKKKFSFKKPFKLSGLSFKRNRKEGGGDSSASSPTEEEQEQGEISACGEEGTAQEGKAAATPESQEPQAKGAEASAAAKGGDTEEAGPQAAEPSTPSGPESDPAPASEQNE
The following text describes a protein:
Function:
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Sequence:
MLEVFFLGTGGIMPTRERNVPAIALRYKGEIILFDAGEGTIRQMNTAKLSPMKVDKIFITHFHGDHYLGIPALIQTMNLWDRQKPLHIYGPKYTFQFVQNLLNSGFFRPGFDIHVHELGETRLKFGDYEIWSFKVEHGIPALGYVFKEKDRRGKFLKEKLREYGLEEGPILGKLEREGKIEWNGRIIRLEDVTGPRRKGLKIVYTGDTEPCERVKLFSERADLLIHEATYLNPGDRGDSYHSTVEEACDTARRAKVKLLALFHRAFRYSYEDYVEEALKICESLGVRAVVPRDFDVITFKSGTWELRNLLEERE
The following text describes a protein:
Function:
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MARNTGSSSGSTPAASSSGSSAAAAAAAAAAAAAASNAKQKQRSPRFSLSSNLILDKWKTMIGCVCLAIASYFGYLGYLETRVNTPFDHQKMVVHAGLEQPDRYWGSYRPLTYFGMKTRDPHSLVMGLMWYTPSNLGPGGQGIRHWCEQGDKLDSYGWTHHDGRSFGVQEIQDLPFELKTSFVKYPEGKQYGGDWTARISVRNTTRAWDKSISLIWYVALDERTNGHIKYVSDDKSPEPGVYGEAQGLGEFQVRFHAVKGKILHKSYLSTVAPSLAKLKDTLFSHFRAFADKRGNRFIGLPGEIVSQNGLPSSNPEPNFIAIQITAEVDFTLDITYQSTSGFSLGESIPKPPTGRAYQDSLQAKIAQFEQRFEDRFQLKQKGHSPEEVRFARNALSNLLGGIGYFYGSSRVQSVYTKNPVPYWKAPLYTAVPSRSFFPRGFLWDEGFHGLLISAWDIDIELDIICHWFDLLNVEGWIPREQILGVEALAKVPEEFVTQRNSNANPPTFFLTLKKLLTSHRAELSQNGRLATLERLYPRVQAWFNWFNTTQRGEVLGTYLWRGRNATTTRELNPKSLSSGLDDYPRASHPTDKERHLDLRCWIALAAGVMAELSTLLGKDDAKYYETASYLTDNVRLNRLHLAPYSEQYADWGLHTDQVKLKRPPSMAPQQQQRHHHQHYQLPEMQRVTGELPTYQFVDSAFGYVSLFPLLLEQLDHDSPYLTKLLNDLRDPEQLWTNYGLRSLSKRSPLYMQRNTEHDPPYWRGPIWININYLAAKALHHYGKIDGPNAALARQIYAELRDNLVGNILRQYKRSGYLWEQYDDTSGEGKGCNPFTGWTATVVLLMAEQF
The following text describes a protein:
Function:
Aminoacyl-tRNA synthetase that catalyzes the specific attachment of isoleucine to its cognate tRNA (tRNA(Ile)).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLWGLHPHGPGTAALTAAGSLWGPARFPSRLGCLGMTRRLVVRSVAGADSPQSSPKSGRYRDTVLLPQTNFPMKLLGHQQSDMELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIVNRFHMMRGSKVHFVPGWDCHGLPIETKVLSELGVNTQTLSAMEIREKARSFAQAAIEKQKSAFARWGVMADWSNCYYTFDPKYEAKQLRVFQQMYEKGLVYRSYKPVYWSPSSRTALAEAELEYNPEHVSRSVYVRFPLLKPPPTLESLTGASSPVSALVWTTQPWTVPANQAICYMPEAKYAVVKCSASGNFYILAEDKISPVASALETTFDVTATFSGVDLEGGTCSHPLIPDKVSPLLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHSLPMDCLVDEEGMFTSAAGPELQNKAVLTEGTDVVIKMLQATKNLLKEESIVHSYPCDWRTKKPVLIRASKQWFVNIMDIKATAKESLKTVKFIPGAALNSMMDMLDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIIKLVEQHGSDVWWTLPAEKLLPEEVVAQAGGPGALEYVPGQDILDIWFDSGTSWSCVLQGTEQRADLYLEGKDQLGGWFQSSLLTSVATRSKAPFRTVMVHGFTLGEKGEKMSKSLGNVIDPDTIISGGKDHSKEPPYGADILRWWIAESNVFTEVTIGPSVLSAARDDISKLRNTLRFLLGNLAGFNPETASVPVKNMYIIDQYMLHLIQDFATKVTDSYKQYDFGKVVRLLKAFYTRELSSFYFSIVKDRLYCESETDPKRRSCQTALAEILDVLVRSFAPVLPHLAEEVFQHIPYVKEPKSVFRTGWISTSSVWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYDVIIVIEPGLLFEIMEMLQAEETSSTSQLNELMMASQTTLLAQEPRERSADAIELTGTFVINLEGQNLTRVRIVEGRRALGRSVQ
The following text describes a protein:
Function:
Participates in both transcription termination and antitermination.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKKEETISLIDTFSEFKELKNIDRTTMVSVLEESFRSVIAKMFGTDENYDVIVNPDKGDFEIWRNREVVADEDLTNPNMQISLTEAQKIDASYEEGEEVTDEVIFAKFGRRAILNLRQTLASKILELEKDSIYNKYIDKVGTIINAEVYQIWKKEMLLLDDEGNELLLPKTEQIPSDFYRKGETARAVVARVDNKNNNPKIILSRTSPVFLQRLFEMEVPEINDGLITIKKIARIPGERAKIAVESYDDRIDPVGACVGVKGSRIHGIVRELRNENIDVINYTSNISLFIQRALSPAKISSIRLNEEEKKAEVFLKPEEVSLAIGKGGLNIKLASMLTEYTIDVFRELDENVADEDIYLDEFRDEIDGWVIDAIKAIGIDTAKAVLNAPREMLIEKTDLEEETVDEVIRILKSEFEEEPAAEMEPETEAEPEAEPTQE
The following text describes a protein:
Function:
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSYYVLPLNNDGKPRPLGKGSLISLPVPNPSYHLRLVVSSVSDISRNGKILTNVPKKGDDFDRTKYQAFEISSSFEKECYVDIPIYAPGAYSFYAEFETPRKDFFNASEESHSTGKTEEYYFNVSSGYTLNGEPVPFSALTLISIISKWMGPYKTWDSKLQFIKDTGYNMIHFTPLQTRGESNSPYSIFDQLEFDKEIFPNGDSDVAELVDKMEKKYDMLAMIDIVLNHTANNTTWLEEHPEACYNVETAPHMESAIVLDDAIIEFSDGVGLVRDPGHLDEIMSNFKDTVSGLDLWQFYVLDVSKNVDAIAAAWSSLSYIDNLPDWAHDLKGVAKYVTEEAVENAHILGARFGKKVDAAKAAGIIATYLSKLESTDAKAFPADMVKSEVKKVLDEVNDPFYKEYNADQVTILDQVKNRVSYTRLDENGPQHGQEVSKKSPLVETYYTRITSKDGKKLHLANNGWMWGANPLVDFASNKSKAYLLRQVIIWGDCVKLRYGKKPEDSPWLWDHMATYVQTCAKYFHGVRVDNCHSTPLPVGQYLLDKARKVRPNLFVVAELFTGSEEEDRIFVERLGITALIREAMQADNVAQLSTLVHKHGGRPIGSFFEQSLAHCTQDGVERVDVAGDRLDINLVRKSNVDALFMDCTHDNNPPAQKRTVEDTLPNAALVAMCACSVGSNMGYDQVYPKLLDVVGEDRAYNFDGGISKIKAQLYAVHEELGRKHAEETFIHHEGQFITVHRLSPIDGHGYFLVARTKFEEHTPEQTIAPITLSGSKAEQVLAVKLVKTGDPEKSDKEIFGIPTKVEELGDADIKFENGTTTITLPDFPAGSIALFKTNYVEVDKEMDEFVRTGADEAVSNFDLLDLNVVLYRAESEERDFSGGKDGVYEVPGYGKLTYAGIQGWVSPLISIVADNNLGHPLCEHLRQGNWAMGYTVDRLGKYEEEYPDVATFKKWLKSRFDRISSLPNFLHPRYFALIIYTAYAALRNKALSLLDSSISDSTIFVQNLALTSIQMIGKIPSASVFPDKVVASLAAGLPHFSVDYMRCWGRDVFISIRGLALCTGRFDIVKSHILGFAKTLKHGLIPNLLDSGRNPRYNARDATWFFLEAIQDYVKFAPDGEKILDEKITRRFPLDDKYVPVDSPEAFQTTSTIREVIYEIFTRHAKGIEFREANAGPDIDSQMKSEGFNQKITVDWSNGLIFGGNQWNCGTWMDKMGESAKAGNKGYPGTPRDGSAIEIAGLLKSSLRFVNELNKKGLFEWTEVENQDGNKVKFVDWEKKVQDSFEHCYWVPEEASQDKDYDVDSSIVNRRGIYKDLYRSGKPYEDYQLRPNFAIAMSVAPELFTVDKALHALSVADKAIRGPVGMATLDPSDLNYRPYYLNSVDSDDFATSKGRNYHQGPEWVWNIGYFFRAFLHFGLAQFEHPSKEARDSVYQQLSSRLEEHRKWIHESPWAGLTELTQKDGELCGDSSPTQAWSSSTLIDLVFDANLIEKN
The following text describes a protein:
Function:
Transcriptional activator. Binds the cAMP response element (CRE). Activates transcription through box-B element and CRE. Seems to function synergistically with atf6. Regulates FGF21 transcription.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MSVSEEMENADLLGLIFPDGEPGSGDLFLKEGNNFLDDFFSEQDMLSGMDTEDFLSSLLGEEDDGVMVNCMSQSPHGSDSGISEDTTPPHCQSPHDGSETDTVPSPGQEPLLYSECVTESYEAQVVQTDHCYTLPQDTNTLLSVRSENPESDVFIDVDDLDASMEDDDFSPELPCSLTIEDSMQSSKLDSQFQFKEIVLTDEEKRLLAKEGATIPSHMPLTKAEERTLKRVRRKIRNKQSAQESRKKKKVYVDGLENRVAVCTAHNQELQKKVEMLHKQNMSLIEQLRKLQAMVKMSTMKTTTTSTCIMVFLLSFCLIIFPSVNPFGSSDQKDLYASSTGMSRALRSYPAIKKDNIISTSAKEVVDQDVLLVATIENNQALLSAGQNHTPDYQRLEQSDSESGVNSNSSSDFPAPPQSDLKADATLSESHRNSGAPPVIYDGQSKSKESWMEQKPTSVIIQQHRSDEM
The following text describes a protein:
Function:
Initiates the restart of stalled replication forks, which reloads the replicative helicase on sites other than the origin of replication. Recognizes and binds to abandoned replication forks and remodels them to uncover a helicase loading site. Promotes assembly of the primosome at these replication forks.
Sequence:
MQYFDIYIDSMKGIYTYSDKNDEFEVGENVIVPFRNIKKAGFIIRKNLKESFEFKVFNISSKVKNSLKLSNEQIKLIEWMVDYYLASYDSVIKAMIPKKIKISYSNIYTINLNKLNILNRFLDNGIIKYMISLTKISYSTAKTKFKKSVVNSLIDKKILYKDENNIYVNIGNFSKLKEENKEIFEYFYKKTIVKKEKLEEKFKKIVIKELEENEILKIEAHINEKKEYISDNTEKVFENKSLLNKKQLAIKENIENSDKKYFLLKGVTGSGKTEIYIELIKKAFFEGYGSIFLVPEISLTPQMVERFQSEFKNNIAILHSSLSDIERAKEWESIYIGEKKIVLGVRSAIFSPVKNLKYIILDEEHEATYKQDSSPRYNAKYVAIKRCLDEGAKLVLGSATPSIESYYYAKTSIYELLSLDDRYGNAEMPNIQVVDMKQEDDLFFSKALLEEIKNTLLKNEQVILLLNRKGYSTYIQCKDCGYVEECDNCSIKMSYYKSVNKYKCNYCGKQIHYTGKCTKCGSTNLIHSGKGIERIEEELKKYFDVPMIKVDSELSRNKNYFSKIYKDFSDKKYSILIGTQIIAKGLHFPNVTLVGVINSDIILNFPDFRSGEKTFQLLTQVSGRAGRGNKKGKVIIQTYEPENNVIKDSKEENYDLFYEKEISSRKIFSYPPFSKILNIGFSSEDEERLLDISKKFYDEIKSQDIELYGPTPSMVYKVQKRFRMNIFVKGSKKKIDKFKLFLKKKLNEFNDTKVRIVVDIDPINMI
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLTRYQIRNEYSLADPELYKAADRDDPEALLEGVAMAGLVGVLRQLGDLAEFAAEIFHDLHEEVMATAARGHGLMVRVQQLEAEFPSIEKAFLSQTNHTSFFSNAGVDWHPNLRTEQNLITRGDLPRCVMDSYEECRGPPRLFLLDKFDVAGAGACLKRYTDPSFFKVETAPSEPSLEVHREKKFRKVKKKGSRWKNGETPEIVPTSHAKLHQLFLEESVEKGLSDPARLVKLKKRQLDASPFNSRSGKSYMEKFLETPPERDEVREISVNPLPLKMASDYSSESGLEIYEITTVSPVKEKSQRKESTCSSPNAHEVVLKPSMDELYGNDRQIVMVPEPGTDGEREEIPSIHPKVMVERDIAVDGEGKREGSVDEDNSDDMTSEVDNYMDALTTMESEMETDHVYRPKSDSGFSNVAKCGVDPDRNGELLKFETHSSDSQSIGNVSASDDGNNSLKKGRSSFSCSDTLSNLGEILPSDGEGSAIVVPASEAFMPEHAEAQSNQFPEDMAVRCIDEDNINSLGEVSGNSSLADSNHPQHPLDPTASSMQHHPDETPSEPTKLGSALSHTDERETNLVESSAIVNDTTSQTTNGSPFTVSAECHSLDKLDAGDCHISSYVSSHLSNYSELAPEDFAEKSNPDNTVNIKIGSPRSNTSSPAEEQVHYSILSEVEDSDVGKRDDLVSEDVDALPETEVYRESDTSQNCNFQEQHISDIVDNVPQDELESVEETPVYSEEANTYCTADIEKIGASTCNVDAVDQEAVPREFPSNYQDCSILEDHAGLDDVVAEGVLVENMAVSATVVSAEAIADDDVDVVYPLQDSLCPPSNDTVNSETEDPLKDGLEFNKVVSHDCLTGLEAENETTQMQVAPKVFDSASCKLISHDESNSEMVKGVQNSSAEVSQNSLPAGDVTIPPTSSGLSDQELESESLHQSHLLDGGANAMSLPAVQLPDPETSSEQPLELQTNQLDSECMAAKASPNSPDHLSEQIQSSIHTDQQRLFNDVSESCQANLPNELSPCGYLQQSTGLEINITEQELDPLSSVFPSSGLLPEAAQVNLEEMPPLPPLPPMQWRLGKIQHAPLSPQREFMDHSQESFPSILPFRDHEKAQSAFPAEQSDIMQSANPFLPVSVVEVEKPNVPERVGDAMQPTLSPLQLPFMAEDANSPNSHPLEGTQSLNPFLTEKPDHGSLASEHELVQLSSNPFLSLPANEDTASEYDPVSSSEKLIHSLNQSASEPGLPHMSENFEGEHGNSSDKSALPPIKVEDTASKNGPVPSPGKPIHLLNQSVSEPSLQHTSENLAREHGNPFDGSVLPPRNVEDAASNYDPVSSLEKPIHPLKQSASEPGLQHTSEISEEEHGNPSDTSVPPPRKVEEQPHRGLSSSEGKSTWPSNPFALLTTSEVGHANGRSTVKLPRPRNPLIDAVAAHDKSKLRKVTERVRPQSEPKVDERNSLLEQIRTKSFNLKPALVSRPSIQGPKTNLRVAAILEKANAIRQATAGSDEDDDEDWSDS
The following text describes a protein:
Function:
Cell-wall hydrolase that hydrolyzes the amide bond between N-acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to hydrolyze the cell walls of several bacterial species (i.e. Paenibacillus sp., B.avium, E.coli DH5alpha, E.aerogenes, L.acidophilus, B.thuringiensis, B.pumilus, B.subtilis and E.coli W3110), thereby showing that it is a cell-wall hydrolase with broad-spectrum activity. May have a role in peptidoglycan fragment recycling.
Miscellaneous:
MISCELLANEOUS: Disulfide oxidation is not required for folding of the enzyme core or in vitro muramyl dipeptide hydrolysis.
Subcellular Localization:
Periplasm.
Sequence:
MIVGVLVAAATPIISSASATPANIAGMVVFIDPGHNGANDASIGRQVPTGRGGTKNCQASGTSTNSGYPEHTFTWETGLRLRAALNALGVRTALSRGNDNALGPCVDERANMANALRPNAIVSLHADGGPASGRGFHVNYSAPPLNAIQAGPSVQFARIMRDQLQASGIPKANYIGQDGLYGRSDLAGLNLAQYPSILVELGNMKNPADSALMESAEGRQKYANALVRGVAGFLATQGQAR
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.
Sequence:
NYSLLFSPLLLPFAPRNAAKLRFACLHATICARHSDRSIDRSMGSSDQKVIGIAAAAAAAAEEAGRRCCVECGATTTPMWRGGPTGPRSLCNACGIRYRKKRRQELGLDKKQQQEHHPHHHQQQQQQYQRQQQQQQQEDHSDAASSVKDSSSSSSNKSSSLQVVKKRRVLMGVEEAAILLMALSSSSPTLLHG
The following text describes a protein:
Function:
Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MEAESNSNPKAPLLVVNERKRIGRLSGRNSVRTLRDEFFNRLPDKVRSGVDVESPFHIDVSKTKGLTEDQKKYYETQFATLKSFEEVDALESDDTIHEEDDEEQLQAERAMKISNYANILLLAFKIYATIKSGSIAIAASTLDSLLDLMAGGILWFTHLSMKNINIYKYPIGKLRVQPVGIIIFAAVMATLGFQILVQAVEELIKNKPTAKMSSDQLVWLYTIMITATVVKLALWLYCRTSGNKIVRAYAKDHYFDVVTNVVGLVAAVLGDKFYWWIDPAGAIILAIYTITNWSGTVMENAVSLVGQSAPPEVLQKLTYLVIRHPQVKRIDTVRAYTFGVLYFVEVDIELPEELPLKEAHTIGETLQNKIEKLPEVERAFVHLDFECEHKPEHSVLSRLPNSSA
The following text describes a protein:
Function:
A mycothiol (MSH, N-acetyl-cysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics. Activity is specific for the mycothiol moiety.
Sequence:
MSELRLMAVHAHPDDESSKGAATTARYAAEGARVMVVTLTGGERGDILNPAMDLPEVHGRIAEVRRDEMAKAAEILGVEHHWLGFVDSGLPEGDPLPPLPDGCFALVPLEEPVKRLVRVIREFRPHVMTTYDENGGYPHPDHIRCHQVSVAAYEAAADHLLYPDAGEPWAVQKLYYNHGFLRQRMQLLQEEFAKNGQEGPFAKWLEHWDPDNDVFANRVTTRVHCAEYFHQRDDALRAHATQIDPKGDFFHAPIEWQQRLWPTEEFELARARVPVTLPEDDLFKGVEP
The following text describes a protein:
Function:
Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSFEAWIIATGVLVGVSCGLIGTFLVLRSMAMLADAISHTVLLGIVGAFLVTGSLDGIYMFIGAAATGLLTAFLVQLLHSKGVQSDAAIGVVFTSLFAIGVILLSVYGANVHLDIEHSLMGEIAFVPWNTVTVFGVDIGPKAFWMLASVLVLNVVLISVCYKEFKIASFDPQMALALGIPVLLIHYVQMGMLSLTTVASFDSVGAVLVVAMLIVPPAAAHLLTDRLLYMLILSALIGGLSAVMGYFFATWLNVSISGAMAAMTGVCYASAFLFSPANGVITKKLRTLNMQKERAG
The following text describes a protein:
Function:
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
Sequence:
MDSVVFYMKVNVGSGNPVKVRATENVLGLIYGNVEVRGVEVESGVPDQPVGLEETVRGAVNRARRAFRDCELSVGIESGLHRVPETITGFVDLQWCAIYDGEHITLGVSAGFEYPPMVVEEVLAGREVGDVMDELTGVDELGRKRGAVSFLSGGLLDRTGNTEQCVLMAMIPRMNPSLYGLK
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLVRFEVRNEVGLGDPDLYGGGGGGGGGVGGAAVGTGAAGKRGAAAAGEEEPKALLEGVAVAGLVGILRQLGDLAEFAADVFHDLHEQVIATSARGRKVLTRVQNIEAALPSLEKAVKNQKSHIHFAYVPGSDWHTQLQNEQNHLLSSDLPRFMMDSYEECRDPPRLYLLDKFDNAGAGACLKRYSDPSYFKKAWDMMRADKTTNHQREKRSQKIKRKGSRLREPYHGQATSRHRSGELQRSLTAGQPVNRPFASPSTDGQSFSEHRSTPDARCNPENISRSSSFSSKTRLSSVDQALDTKPSTVPHENGHGKSSNTKLHKPSDLPLRIQHSSTSVDDAGDDLKQGSLPDDVVARSPYVKWDEKAAIIMSTSSVYCDDVVMDKAEDAEPTCISSAQKEIDHKGMDTLEQQDALLKKTKSPLVLNHHDEIPGETDNYMDALNTLESETETEAESQTKNQVMPLPSFNAEAPQVGATDDIVSQHPDSSVADFTDTCQDSNISCTSERAVDFPHLSNADSPEISQLEFSEYTSVTTYKESSVVTKIHESSMEGACGDPYEISEPELQVHTAIPPNGRSPVHNQIPESKAEDGLGDTPEIPEPEVTYMVIPSNEESAVANQNLESNVENTGDFTDDATDDVVSGPTISNVVIDEEAFEMAPAAKSSPGDIANESWVVSESRSQDYPGEKHEELGDCGVSEVSQSWSEPRNEPSENRSATQDVPTNTSTTSTGASEVSNSQGEPLKEPLENRFATQGIPTNTSTASTVVPSVKLWTNAGLFGLEPSKPPVFGAQDTPREDTPPGFEVPQPSHSTEFTELHCSKPIESAVVDVPNGNTSITSSFVGKLVGIRPGSTNLNGTGANQSAARIPDQVHSRTDGPSDFSSSSFEHNNMIGKQTSISELLESEESAENCTEMYSTNMRNDMHMVSASSFSSIAQRFLANTLQRRTSPKYTDLPMSSERPNADASVNDESTLNPIAEPSGTVFTDESQFENRSENGMNGLSKSSIFSSRQYSEKSSPPLEYMKISFHPMSAFEMSKLNLDFCDGNLHENSDDMMLPTFQLLSESSIPQPGSGSESEDDTFGRSYSYSSYDDLSPRLYSNSEVWDQEDGVGLEEHELYGDSNQIGSSTVPLSSYAGFEQMNLSGVKSTISLADIGDQNGLGTLESHSVEELPNFDTLMSRNDDQNDEASIPHNPLNLPPAEDQLPPPPPLPPMQWRMTRQTTPLEEERGITAKDMFRKSSCLPHVHTSAQEEHPLPAALQDPQGHAKEVDVQKTDGVKEIINPSSIIDIKSSLLQQIRDKSEQLKPNGHERSKTVGSDIKSLDEREELLQQIRSKTFNLRRTNASKTDTSSQSTANSNVVAILEKANAIRQAVASDEGGDDDNWSDI
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Miscellaneous:
MISCELLANEOUS: Present with 7700 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Sequence:
MLRRSIHTTKILQKPNATSHIWSDFTTRPSSLSIQSSKVKNYLFQKKASLDPPSISRRSNRIKYSPPEHIDEIFRMSYDFLEQRSSKFYELANKTKNPLKKDALLIKAEINNPEVQYNFQFNNKLNNVKDIIDYDVPVYRHLGKQHWESYGQMLLMQRLETLAAIPDTLPTLVPRAEVNIKFPFSTGVNKWIEPGEFLSSNVTSMRPIFKIQEYELVNVEKQLYTVLIVNPDVPDLSNDSFKTALCYGLVNINLTYNDNLIDPRKFHSSNIIADYLPPVPEKNAGKQRFVVWVFRQPLIEDKQGPNMLEIDRKELSRDDFDIRQFTKKYNLTAIGAHIWRSEWDAKVAAVREKYGLPPGRVFSRVRR
The following text describes a protein:
Function:
Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
Sequence:
MATSDLVDHSPRHPTKAAQLASASNVILIDNYDSFTWNVYQYLVLEGATVAVFRNDEITLEELIAKKPTQLVISPGPGHPETDAGISNAAIKYFGGKIPVFGVCMGQQCMITSFGGKVDVFGEILHGKTSILKHDGKGVYEGLPPAVEVTRYHSLAGTHATIPDCLEVTSTVPLNDGSGKDVIMGIRHKQYAVEGVQFHPESILTEHGRTMFRNFLKLTAGTWEANGKSSSGSATVNGSAPKVDKKTSILNKIYDHRRAAVAVQKLIPSQRPEDLQAAYDLNLAPPQISFPCRLRQSPYSLSLMAEIKRASPSKGMIAETACAPAQARQYAKAGASVISVLTEPEWFKGSIDDLRAVRQSLEGLPNRPAVLRKEFIFDEYQILEARLAGADTVLLIVKMLSVELLTRLYNYSRSLGMEPLVEVNTPEEMKIAVELGAEVVGVNNRDLTSFEVDLGTTSRLMDLVPESTIVCALSGISGPKDVEAYKNDGVKAILVGEALMRAPNTSAFVAELLGGNSENNSKPAPSSRLVKICGTRSEEGARAAIEAGADLVGIILVEGRKRCVSDDVALRIAQVVKSTQRPTVEPDSTSPANTFSSDFFDHSTRVLRHPTRALLVGVFQNQPLAYILDKQQKLGLDVVQLHGSEPIEWASLIPVPVIRKFALDESSIARRAYHSLPLLDSGAGGSGELLDQSHVQKVLDGDDGLRVILAGGLDTSNVVDTIRKLGDSGHKVVGVDVSSGVESDGSQDPAKIRAFVQAVKAYEA
The following text describes a protein:
Function:
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
Miscellaneous:
MISCELLANEOUS: There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).
Subcellular Localization:
Cell membrane. Cytoplasm.
Sequence:
MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSGVTR
The following text describes a protein:
Function:
Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is required for E.coli to grow on glycolate as a sole source of carbon. Is also able to oxidize D-lactate ((R)-lactate) with a similar rate. Does not link directly to O(2), and 2,6-dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as a primary electron acceptor during glycolate oxidation is unknown.
Subcellular Localization:
Cell inner membrane. Note=Glycolate oxidoreductase activity was shown to be firmly associated with the cytoplasmic membranes.
Sequence:
MLRECDYSQALLEQVNQAISDKTPLVIQGSNSKAFLGRPVTGQTLDVRCHRGIVNYDPTELVITARVGTPLVTIEAALESAGQMLPCEPPHYGEEATWGGMVACGLAGPRRPWSGSVRDFVLGTRIITGAGKHLRFGGEVMKNVAGYDLSRLMVGSYGCLGVLTEISMKVLPRPRASLSLRREISLQEAMSEIAEWQLQPLPISGLCYFDNALWIRLEGGEGSVKAARELLGGEEVAGQFWQQLREQQLPFFSLPGTLWRISLPSDAPMMDLPGEQLIDWGGALRWLKSTAEDNQIHRIARNAGGHATRFSAGDGGFAPLSAPLFRYHQQLKQQLDPCGVFNPGRMYAEL
The following text describes a protein:
Function:
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Its dissociation from the complex determines the transition from state pre-A1 to state pre-A1* (By similarity). May inhibit mRNA translation (By similarity).
Subcellular Localization:
Nucleus. Nucleus, nucleolus. Chromosome, centromere. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Cell projection, filopodium.
Sequence:
MAATAVGNDVIDRDLPTAVRLLNSLTEQIVSVTSHVRELIKKVREKAYQTSKGLSFLDLRYHLLLFYLQDITHLISLKTEGESLKDNSAIHRLVTIRTVLEKMRPLDQKLKYQIDKLVRTAVTGSLSENDPLHFRPNPQSLVSKLSESEDSDDDGVGGKTKEQKEPSGGRRYVPPRIAPMHYDGDLTEADRQKERVEKQKRAALRSSVIQELRQQYSDAPEEIRDRRDFQTDRQGREELNRKNYEESMMVRLSTTRDQKLRKRGMMGMTSQLSNITRFSDITALTGGEVQDIGNPKPKKKKIIKKGKKKVFRKRK
The following text describes a protein:
Function:
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKHLHRFFSSDASGGIILIIAAALAMLMANMGATSGWYHDFLETPVQLRVGALEINKNMLLWINDALMAVFFLLIGLEVKRELMQGSLASLRQAAFPVIAAIGGMIVPALLYLAFNYSDPVTREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALAIIDDLGAIVIIALFYTSDLSIVSLGVAAFAIAVLALLNLCGVRRTGVYILVGAVLWTAVLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSLQGVTIDGLTSMLPLGIIAGLLIGKPLGISLFCWLALRFKLAHLPQGTTYQQIMAVGILCGIGFTMSIFIASLAFGNVDPELINWAKLGILIGSLLSAVVGYSWLRARLNAPA