lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in inflammation.
Sequence:
MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRNTSKDEHEELQRLLDPNRTRAQAQTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIRYMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSITQTTTSLYAYFFSNLFSTAEVDLADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDCGGCTTFTHLSFQEFFAAMSFVLEEPREFPPHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLNILEDEELQASSFCLKHCKRLNKLRLSVSSHILERDLEILETSKFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPEWVLQDLIIALQGNSKLTHLNFSSNKLGMTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLTSIQHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQNRSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHNHNVKILDLGENDLQDDGVKLLCEALKPHRALHTLGLAKCNLTTACCQHLFSVLSSSKSLVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG
The following text describes a protein:
Function:
During the asexual blood stage, recruits host complement factor H CFH to the surface of merozoites resulting in the down-regulation of the host complement alternative pathway and thus, protecting merozoites from complement-mediated lysis.
Subcellular Localization:
Cell surface. Cell membrane; Lipid-anchor, GPI-anchor. Note=Present on the surface of merozoite.
Sequence:
MFAVNLKICIFLSLVSFLLQCKNTLANVTFEQKVQTNLSHDKNGDIVYGHREFKGGIYAFLGYDNCTIEVNKTVNGIDWNEKKDVKVSGNNNIAVVYSIFTSEEKMILIFKCDNKFYITKYGKEFKWSDPKVIDVSNVIGTNTTPAVYSGSLLSMNNDFEKYILVCENHSQNYINVVDQEYMREIRLLGKCMLSFDEGNNWKNEVMNLYSDEGYTKINTLRLSDYGGKILVKGTNAQNLNQTIRSIILLCSNLHDWKLFCGLPTIRFRKDISVENLTYLNTYHLAIVKNEDKLQLAFTYDLFETFDPQYLNTEFNGVSHYFVLAPDEMVYLFYHGNEKKNYVIKIKTVPRKIGCELNTNDTVNKIYTYTYKYIYNNKLSAKTCKVPSSHLKYSSDGLYKLFEVRLPKDIKVTENCFRYSFLSDLNNKYHTTIIKTRVINKLEDYVEVQFHFPIYYTKFLYNYKSTYCVLSNNYRIVVEFDYIRNHIDLDFPFDTDTVKLYSNESVTHAFRNNTEKTHVHKFPKGTYMTSYFSYEKEYVISNYIEEPFSTTFTILTQTQMNVHFMAGGQKYKYEGIDLTDSSPNYELSLNSLSDSQNVDIFVSKFDNNKTIGFVCPVKSSYDGLNCFDNVYIKNKTLVKIEYLFGENDIFVVPQRRIYKTEGTAMESLLYLNNNNVKKLIDDKSIIHFYCECNVNNNVIKVNYYISPFYDENSIKQEINKKDQEITMINKTIPQDEKDILFNNEKVVPLSNEPQEIIQPPIQEKLNTTDPSKAYIYGANIIFIAIISIISLSISSFI
The following text describes a protein:
Function:
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
Sequence:
MPIKFDRPAVTDSAPDLSESLAALRDKAPILAKFEKAPLGVVLGSGLGGLADAIESPTIVPYAEIPGLAPSTASGHRGEFLIGHLASRPIIAMAGRLHVYEGHSLRDVTRPVALMAGIGINELVVSCAAGGLNPQFKVGDLVLLSEHSSWLDGKLGAPPISFQQPISFQQPNDLPNESDAAAKCFRRSLNTCDPQLDAIAHQTAHANGFELRRGMYLAVNGPNYETRAECRMMRQLGADLVGMSTVPELLCANSAGVRTLGISVVTNLALPDAPATADHADVLEVCERAANRLQQIVRAIATHGA
The following text describes a protein:
Function:
First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
Subcellular Localization:
Nucleus.
Sequence:
MSSPQLAPERSIFGVDPLDDFVTIVGDWIYTKGRGRSNLEIEAKIGQIISQETGERIHLPVRNETIVDLSHTRFESQMSASQHAHYNRILNSLALRSSEGSYTGAKISYHRRKEIDYFHPAPKGKVRVTRDAETLAIKPDGIIQKQRIADLDIYCPYRLFDYRISINVELPAPEPTSDHVSIREKNRLSYAHQNFIVDLTQVTLPEKPSDHINELEIEIRDVDQLMQAAAQAKSIPTNTSAPSSQDWSSFDDQVLIFLNNIRLLIRNAPADERR
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MMPVELGQALLLLPPPLAKAEDSPFSGPDATPRGELSNPETARQLFRQFRYQVMSGPHETLRQLRKLCFQWLQPEVHTKEQILEILMLEQFLTILPGEIQMWVRKQCPGSGEEAVTLVESLRGDPRRLWQWISIQVLGQEILSEKMESASCHVGGMERHLEVMPPELGLHDSTCRPLEPPGHTVKEECDVEQELVMAAAPPPAPPEERLIRDQDFGASFLQAASPEQWRHLDSTQKEQYWDLMLETYGKMVSGGISSSKSDLTNSAEYGEELAGLHLHVSEKIPRPTLIGDRQENDKENLNLENCRGQETSDVSCQVSGEAPSQASLSGLLSEDEPRCFGEGDSLPEALENLQGEGPVGQLSPQGRNSGKQHLANPHPEELSLLWLEEKREASPKGQPRAPMAQKLPTCRECGKTFYRNSQLVFHQRTHTGETYFQCPTCKKAFLRSSDFVKHQRIHTGEKPCKCDYCGKGFSDFSGLRHHEKIHTGEKPYKCPICEKSFIQRSNFNRHQRVHTGEKPYKCSRCGKSFSWSSSLDKHQRSHLGKKPFP
The following text describes a protein:
Function:
Catalyzes the reduction of NADP in the presence of molecular H(2) to yield NADPH.
Sequence:
MSMLTITIDGKTTSVPEGSTILDAAKTLDIDIPTLCYLNLEALSINNKAASCRVCVVEVEGRRNLAPSCATPVTDNMVVKTNSLRVLNARRTVLELLLSDHPKDCLVCAKSGECELQTLAERFGIRESPYDGGEMSHYRKDISASIIRDMDKCIMCRRCETMCNTVQTCGVLSGVNRGFTAVVAPAFEMNLADTVCTNCGQCVAVCPTGALVEHEYIWEVVEALANPDKVVIVQTAPAVRAALGEDLGVAPGTSVTGKMAAALRRLGFDHVFDTDFAADLTIMEEGSEFLDRLGKHLAGDTNVKLPILTSCCPGWVKFFEHQFPDMLDVPSTAKSPQQMFGAIAKTYYADLLGIPREKLVVVSVMPCLAKKYECARPEFSVNGNPDVDIVITTRELAKLVKRMNIDFAGLPDEDFDAPLGASTGAAPIFGVTGGVIEAALRTAYELATGETLKKVDFEDVRGMDGVKKAKVKVGDNELVIGVAHGLGNARELLKPCGAGETFHAIEVMACPGGCIGGGGQPYHHGDVELLKKRTQVLYAEDAGKPLRKSHENPYIIELYEKFLGKPLSERSHQLLHTHYFKRQRL
The following text describes a protein:
Function:
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Sequence:
MQLCVALDLEKKEDNLSLLQELKGLDLWAKVGLRSFIRDGAVFLDEIRKIDENFKIFLDLKLYDIPYTMANAALECAKLDIDMLTVHLSSAKSALTALMQRLNALKKRPLIMGVSALTSFSEEEFLMVYNAPLKTQAIKLSAMGKESGIDGVVCSVFESLAIKEALGKDFLTLTPGIRLDQNDKEDQERVANAKEAKQNLSDFIVVGRPIYQAKEPREVVLELLKDC
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAPLALLTPLVVRTLLTLPFPHTYFQPDEFYQALEPAHYHVFGYGYLSWEWRDLPLAESLAHTDVSELHGKLWGKLVAVAAGGRMRGWAWPGVFVVIYEVLKGLGLDRGRFLTMVPRAVGIIIAALTDYYTYCLSSKLLGHGSAPTALFLSLTSLFNGHLLPRSLSTSPETLLTLMALYYFPFPAPGVPEVYGLQNVTNLKPIGASKSRRETEGGEKEFMRVEDSDKSSYGVNDLDYVVIDRAPPFVVEAPQHKDRLVLSICLATLALCIRPTMLSLWAFLGANLLWRRFQSSGLQSLIGTTALAMSSILCTVAGSTAIDYLMSGRLYVPLLTFIYQNVIVNISSFYGSTDHLYHLVQTLPIMLFPLWIWWAKGFIACILPASLLPAQLNKFDKPKGLKILAKAISFTIAVLSLSPHSEWRFLHPLLPPLLLYTIPSFSISYTPTVLGAYYPVRSFRQYLRMDKVPFYVILLSGIVPFIYLNVFHGAAQVEVMNILRRGDLGNVTSLAVLAPCHSTPWMSHLHKDIEGWFLTCEPPVGVDAKMHRTQQDWFYSNPVQYLSSVFPYPPSQLHDISYASFSKTYPSHIILFGELLSRRGIVSETVLETGESQPVITTREGDVTGELESLGYQEVWNGWNGFDWAQDEEERKGGVRVWRLA
The following text describes a protein:
Function:
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
Subcellular Localization:
Cytoplasm.
Sequence:
MTRRYYVPDLQTQVPVVQLPDEEASHASRVMRVQTGDQIELFDGCGHQADAEVVSVSKRECVVRCDAIEAVDREPSIAVDLAIGLPKPDRAKEMIERLTELGVARVFPIVFERTQRPPKENFLDKLRRIVIESCKQSGRNVLMTIESPIDFVSFTETLAASSATNDEEDPQPRQWSWQRVLVAMPDSPPLSATDVEPTGVRQTGAAQTGVGQSDARQINTGQSGLNDRPRTLALIGPEGGLSEAEHQRCVDVGAESIGLGRRILRIETAAAIIAARLVVD
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
IMVDAADYQPLSGDAPVIANMQEFFLQGSVLDTCVDKIHERLQGLCDNVSPEAFTDHERTYVMRNTTSNMPITVKACQSLVDKSAVPWQIKYMGNTDVGDRTKSAMIRSSVSVAVSKDPSEFLEDLGFVLQFEVILKGYFYRKGRLKITVAKLSGSIDPNKHEAGNMSHLIEVSALASPLDESAGDEVRIFSQFLRPIVFLDKVDVRRLQ
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MGRKACCDKSETLKRGKWEVEEDEKLINYINANGEGSWRSLPTNAGLKRCGKSCRLRWINYLKSGLKRGSFTPHEDETIVKFHNTFGNKWSLIASNLPGRTDNEIKNYWNSHLSRRTYLFRSTAVVDSKFIKTHPTKRKKIVTNNNNNNNNEVPAKKKKITSPPPVSDERESNTLHEDSSLSTCSSINTADEFMLDEEMMVWDEHTLMQFHNFLQDHDNGGGGGGGGDVASSCLTPTNDEREKVIVNNNNISDEKLVKFESEEEAETTKTTTMQMQYSCPSPIVIYFDDDEQFRWDFDGGFGGDEVNYPWSETKEEETMFNI
The following text describes a protein:
Function:
Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting.
Subcellular Localization:
Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. Mitochondrion membrane; Single-pass type II membrane protein.
Sequence:
MSEQQSCYCAPCQEFLSICTIKRPVYPLDPVAPDHSEFFLIDSNVRIRVVHVAPENGLKLPNLDLHQGAKRSSLSEEYWFTKWNKPLKIGICRCSFRRSFRLSVAENRDSFEAAPKRIVDVESFVERIIQDTIFEAFQEYYVLRNQNGVINLAYQKSEDDGVVLRKPVTRQPKQCLHKKYAQKKPVIILFHGIGNSADVWWPVIHTLANKGYEVIAPDMLGHGFSSAPNKPNSYTFHNLLIHAITIFDHYTASDDKRKCILIGHSYGCSIVTALYRHRAPQISQLILISGGGPTPLAAPVKNSEISPFGCIHTLFKPLLFCGLKRSFLFSSRGKHFEVCEGESAIPPRILEYISRGQNWPEGDAAFHRRILVPTLLVHGLQDKNVTLVQQCEMERTIPRAFLELIPNAGHMAMIETPEHLSHMILCFIDTWS
The following text describes a protein:
Function:
A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Acts as an omega and omega-1 hydroxylase for arachidonic acid and possibly for other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. May down-regulate the biological activities of N-arachidonoyl-serotonin, an endocannabinoid that has anti-nociceptive effects through inhibition of fatty acid amide hydrolase FAAH, TRPV1 receptor and T-type calcium channels. Catalyzes C-2 oxidation of the indole ring of N-arachidonoyl-serotonin forming a less active product 2-oxo-N-arachidonoyl-serotonin.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MSSRLMPPGSLKAIKATQPQLYIFIGHNYSREKGNSPRRENYTQLTMFLAFAMNVVKVVAGVLDISTVLVLLVSFLATAVLLGRLKRPRLPPGPRAWPVIGNLPSLTKQPHLKFTEWRQQYGDVYTVRMGSDDVVIVNGWEAVREALVKQADEFADRPRLFVFDRIGHGGKGVIFGHYNSAWKANRKFLTTTLRDFGLGKKSMELRIQEEANELCNWLASYNGRPIETGNLLSNAASNIICSVVFGSRFAYDDQDFRRMLDLLERGTRLSMVGQIFNFFPWARFVPFLSRLGNEVMDNCDKIDDFLKKIVQKHQDSFDPEVKRDVIDAYLHQMWRGMDLNSNDLAGNFSEECLVALIFDLFIAGTDTSMNTQRWALLYLATHPDIQREVQEEVDRVVGRDAPVSLAHRPEMPYTDAFLHEVLRIRPPGPLSVPHMAGPGATLNGYEIPQNTQVYANLWSLHMDPEYWPEPERFDPARFIGPDGKVLTNPPSYAPFSLGRRACPGKQLAKSEAFLFLVTMVQRFSFKLPEGAPVPPMDGVMGFSLAAQPHSLCAISRN
The following text describes a protein:
Function:
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Confers resistance to soil-born pathogens (e.g. the root-penetrating fungus Fusarium oxysporum) by regulating membrane trafficking, specifically mediating ABCG36/PEN3 exit from the endoplasmic reticulum and subsequent relocalization at the host-pathogen interface of the plasma membrane.
Subcellular Localization:
Cytoplasm, cytosol.
Domain:
The BTB/POZ domain mediates the interaction with some component of ubiquitin ligase complexes.
Sequence:
MVVSDGGKRVKLNVGGEIFETNASTIQSSCPDSLLAALSTSTSHGSNPVFIDRDPEIFAVILNLLRTGRLPANSSGVFSKQELLDEAMYYGVESLLRLAMLPPPLLGFDASLVSTIVPAADGVPSALTATAGDASLWIAHGGQISVYDWSLSHAGTVRTHLNDITSICRVWGEAAAIGSGSASGLHFYDLSGGRYIGSTHWTDPEDPRIHKARVAAVADSEGGVFASFDCLHRENSVLQIDKSTLQVAAVIGQQSGNSAKTTVPEKLRWLPAKGLLVGSAVQRGVFGCSGYIRIWDPRSRNIVWETNEPGSGRSTRFGDALADMDVDVEDSILFKVCSKSGDLGMADIRKLGEDPWVYMSDENPGAWKAGDGGGYSVVHCYRKQVLAARGGALEVWSSVKEKTSGDPIRRRNFVDKEDDSKRGMISKIEAGGDRLFVSRECMEGVEVWETSSFSGVVSVE
The following text describes a protein:
Function:
Probable transcriptional factor. Binds to the promoter of the SQUAMOSA gene.
Subcellular Localization:
Nucleus.
Sequence:
MEMGGSSGSSESQLLKIGLQFGKEIYFEDVGVGAQVKSDDGLSPASGGDAAGGPQKKGRTAGGVVSGFGQQQPPRCQVEGCNLDLSDAKSYYSRHKVCGAHSKTAKVIVNGLEQRFCQQCSRFHQLPEFDQGKRSCRRRLAGHNERRRKPSLLSTRYGTVSSSIFENNGNSGGFLMDFSSCSRGRIQWPGTRAAPPPRAAIDLPIAGEKFPPLPWQSNLDNPPPYVPPGGCFNGVHEDSNCALSLLSNHSSGSRNQSLSHEYYINPEAGAYVHQLHQPTTGTGAGSGTMVEVHYSTTATGWVYETHDAHLGLGHVPQSGGGYSGEVGLGLHGGGRRYDSSVDHIDWSL
The following text describes a protein:
Function:
Stress-activated component of a protein kinase signal transduction cascade that promotes programmed cell death in response to ribotoxic stress. Acts as the proximal sensor of ribotoxic stress: directly binds to the ribosome, thereby acting as a sentinel for colliding ribosomes (By similarity). Upon ribosome collisions, activates the stress-activated protein kinase signal transduction cascade, leading to programmed cell death (By similarity). Acts by catalyzing phosphorylation of MAP kinase kinases, leading to activation of the JNK and MAP kinase p38 pathways.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSTPTSNESTSSSSNNSDQRVLFPDIQRDDIQVGDHIGVGTFGAVFSGNWTLPDGSQRTIALKKVFVLEKEAEILSKIRHKNIIQFYGICKATGNDFFIVTEYAEKGSLYDFIHSEESQSFASSSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDLTHSCTAPSWGGTAAWMSPEMILQSEGLTTATDVWSYGVVLWEILSKEVPYKDYSEFRIFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGELNRLAGNQKVMDECEKFMGLEDWKTEIEKQEKNVEKMRKDLEKRREQLEIREKALKQRMKVEQAVLDSARHPPEDVHQWSEHHTSHWVETVLGRVANDKKFLDRVNAAVFRNRITGARLLGMTQNDLEHLGVHKVGSRIELMKMIRKLADTQKALHNFPTLEQAKRIEMTLKTEKEAAGQLANDVDIVIIVGMYVRKMNATRRKFKFYADSDWIDDTDIPAKSKSKHASSLIKTVCFSVLDENTKKPINEPACSISSGMTTNPDWITVDTEDDVKIRVIVSVYYADIVTQPRNTEVIKVVTSLEESKILEERHVHLRLRRSSSSASISTPSPVIAPVYHPFGHLNNGFHHTTSSPQLRGFWHRKQTGMNRHGLTETELSSLQEQLRTPSPDKKVVDENVIIHVPKLTRRRRTTTTNSEDTEKSDTNNKTPESQARRVHVHGGKDKWNWKKGKSRPKFT
The following text describes a protein:
Function:
Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKTNPAKKPLYVDGLSQEISETVLQNQFSRFAEVSDVEIITRKDDHGNPQKVFAYISISVAEADLKKCISILNKTKWKGRTLQIQLAKESFLHRLAQEKEEAKAKKGKSTTGNINLLEKIGGVEFHMKAAPGTEVPGYKNWVVSKFGKVLLVLHLKIYHKCKIIKYDPSKYCHNLKKIGEDFTNTIPISSLTWELEGGNDPMRDFSDFHGPPKKMIKVQRDESSTGSLAMSPRPRWVIERPPLTQTSGLETAKKRSGISDDYIDSKDELRMMVAKEENLQRTTQSSINESETDPFEVVRDNFKSGVHKLHSSTGLGIKNNASCHDSDDDITRNDCEYDSGDTDEIIVMKKNVAKVKNSTEFSQMEKSTDKKTSFKNRENLQERKGNVESALGHGLKALNRKSPSRSNSNEDADSASELADSEGDKEYNAMMKNRLRVNLTLADLEQLAGVSDEDTESDGPETTTQCKFDRGSNSPKTPTGLHGCRHCICPEDTVASLLEGEESTCEFQVFKGVGCLYEKGDHIHGRWVPICEWPNYIHQDCKAVSTSSSEKRSKNSISSLLPLKGKKSLSLSAKTHNIGFDKDSCHKASEEERSDSSSLTSLEKSPKVSSKDTQEIKTDFSLSISNSSDLSAKDKHAEDDEKHLAALEVRQKLVDNALANLDGHPEDKLTHIIFGSDSECETEEISTQEQRHPGEEWVKESMGKTLGKLPDSSDDEESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFCMNSRFLESDSEDEQEEVNEKKPARKKSLLKKKESLDVVQSVLKINLSNSTKDQKLKSYVRLKRKRTHPGMRSVVKINLRKSRTLQLTSGAEQPSRFTFSFFDSDTKDIKEETHRIETVKPGKIEDPRFQDSSSEEEDVTEGTDHRKSSPGEAPLPEKETTRFFFFSKNDERLQVEVGSDLFWRGVGSNISRNSWDARTNNLRVDCQKKHKDAKRKMKPK
The following text describes a protein:
Function:
Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.
Sequence:
MLGFRFVCKTGMTYNQRKRPDLENHFLLSKSPQSNMGSHEATAQAFHGAVIHSLSTPGHDLEILPAALLIVEAQGVITAFHKDVKPGEVGSLIDTATTTLHYLSPSQFIIPGFIDTHNHAPQWAQRGLGQGQHILDWLSAITFPNEGRFRDPSHAQRIYSSAIDGFLRQGITTASYYGSIHPEATNILADLCLAKGQRAFVGKCNMTRNSPDYYRDASVEQSLRDTESCIAHIRKIDPEGMLLKHVLTPRFAISCDADGLAGLGQIAAKNPDLPIQTHFNEAEQEITATRELFPQFSSEADLYHHYGLLTKRSILAHCCYMAPHEFDKLKELQCGVAHCPISNMTVGGGFMAAPIREFLNRGIKVGLGTDSGGGFSSSMLDAIRQAMIASHAREVESKGRDKGLKIAEAFYLATLGGAEVCCLEDKVGNFEVGKEFDALVVDWQRDGVMTIVEEEDELDTVFEKFVMTGDDRNIVRVLVKGRMVREVKI
The following text describes a protein:
Function:
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG.
Miscellaneous:
MISCELLANEOUS: Present with 414 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MWLSKFQFPSRSIFKGVFLGHKLPLLVRLTSTTTNSKSNGSIPTQYTELSPLLVKQAEKYEAELKDLDKDLSCGIHFDVNKQKHYAKLSALTDTFIEYKEKLNELKSLQEMIVSDPSLRAEAEQEYAELVPQYETTSSRLVNKLLPPHPFADKPSLLELRPGVGGIEAMIFTQNLLDMYIGYANYRKWKYRIISKNENESGSGIIDAILSIEEAGSYDRLRFEAGVHRVQRIPSTETKGRTHTSTAAVVVLPQIGDESAKSIDAYERTFKPGEIRVDIMRASGKGGQHVNTTDSAVRLTHIPSGIVVSMQDERSQHKNKAKAFTILRARLAEKERLEKEEKERKARKSQVSSTNRSDKIRTYNFPQNRITDHRCGFTLLDLPGVLSGERLDEVIEAMSKYDSTERAKELLESN
The following text describes a protein:
Function:
Thought to regulate endocytosis in coelomocytes through modulation of phospholipase C activity. Possible acetylcholine receptor.
Subcellular Localization:
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Sequence:
MDLSTGVALLSMFSLNIQLEPSPGEMEKRYEAETKLREDITKRFDDTMPIKKDGYLQLIPLLHVDHIHDIQDEQGVLKMALTFTFTWMDERLMWNPSNYSGIRTFSTTRHEMWRKKFWTPTLMMTDVPNSRRPSDVFKPFDMDIYISSSGMVRTSARMMLTIPCRTGFGSYPNDYKNCTFTLMSPYYADQFRFAQWGGAEFTRYLMSSRVTDVLDFQLINIDTRNYYMFLGSEVVDDFSKFKPRHCRSFYRYNLVLKRVNKFVSVQLIAPISVIAVFLAISGFLPHFYGLVCAGSALVYETIFTYDVEQVLPKDYSGMPMIAILLCFLFAETIVLLAWKVFSINTRSHTVFTAFPEYFDDEITSKKEKLLKFVIWVDKFLMVALFVQSFVVMYLARI
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Sequence:
MKNKQIDTEEIVKQVLSNVSESFEELKQNFDWQLGIDEAGRGPVLGPMLYASCYWPTKYHKLISETCKFVDSKQINEAARDKLFDVLTQLKGKVLTFETRELTAEYLSKNQLAHLTINLNDISHNTAAELIQSAIQKGYKITEIFVDTVGPKQTYKNFLQGKLQEIGKEANIVVEEKADSKYANVSAASICAKVTRDYRITLIQQEILPNDSIGSGYPGDPKTKKYLENTNIPFFVYPKYVRFSWQTIKTIINDRDLNIDYKDEQEAAKQVQKLPDYFNVKATKYSYRSLLFSNCIL
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, leading to degradation of nascent peptide chains. Activated when ribosomes are stalled within an mRNA following translation of prematurely polyadenylated mRNAs. Acts as a ribosome collision sensor: specifically recognizes and binds collided ribosome and ubiquitinates the 40S ribosomal proteins rps20/uS10 and rps3/uS3. Catalyzes 'Lys-63'-linked polyubiquitination of rps20/uS10, promoting recruitment of the RQT (ribosome quality control trigger) complex, which drives the disassembly of stalled ribosomes, followed by degradation of nascent peptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MSPSGPNLNNKEHNRASEKKNSRTHNKKTNRNQSKEKPVSSRSVETPKNAVCLEPVGTDPVSNVATVDASKEEQDEDEQICFICAEGITYSCVLPCNHRMCHVCALRLRALYKTKECTFCKTEWDTVLITKDHEIDIHDVDLAKLPFQDEKLGIVYSDEHAQEESNLLLQFNCPEDACDITCKGWFDLKLHAKVKHHKFFCDLCVKNKKVFTHEHTLFSKKGLTKHNEVGDQGSDLEITGFKGHPKCEFCNTHFYDDDELFKHCREKHERCYICDQVAGRPTHQYFKNYDSLERHFEKDHYICRERECLERKFVVFGTEIDLKAHQLDEHPHNFTQRELREARRIIPQFSYDPPGASGRNRRERTSSTPSEQSTSVNETANSLSNLHLSRGEIAHLRQEEYVREQQARHRDFGFTLSNPAPTSARPATSTRTISRGKTRTLRNEDFPSLAEVANQNSSSAPSVPVSAPRLSGKSASRNHVPSPPKGTKSPMASSEQAQHQQVIDRMQKLTNYDDHKINDFKFAVSSFRGNVMPAREAVARITKLVAKPHEQLSGVFNQIANLLENKEKSRELLEAWQEWKILNAKDDTRIGTTNSNLLRLKRSNRTAAQTASVWNRIERAAAHDGPSLSAPSSSINLANITSRPTNSSAANTPSWGVRKARASALNARSEEDFPALPPSTSKRISVQLGKKQARPVDSWGSTPNTSSNRNSNTMGVSKKKNGKKQTVLFHIG
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere. Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MEGQQKLKTKNGQKKTKPKKKTSSTIIVQQDNYNNMENSGYNSQNDSEFDPSSSSSLSSSSSQQIVNNNQPLITNITTPPNNNNNNNNNNNNQILEDIYSDEYCENQMKCMEGFIKKWKDEYIGSIKGNVEHHQIELNNYTFQLSELKQERLFLQQYKESNQRTIELQIIQLQRINNEIESIEKNRHQLPIDLESKKLKYQEETQRILTLSSTIKSIEDQTIKQLLDLDYPLTLFKNYLGLEFQKLSNGDGLKLIFTKIDRNNHNREFTISITVDNLTDQYILVNCNPMISDLDQSIKKLNETGNFSFFVKSIRKQFVNKTIHK
The following text describes a protein:
Function:
Involved in peroxisomal proliferation. Promotes peroxisomal duplication, aggregation or elongation without fission.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MDPKPSPTPQNANEIPNKQGQRDFLNHLEVYLAKRDGVDKLLKISRYATKIILASSVLPETLIVTKRLKSFESSVGLSRKAFRLGKFVQDVNALRGSHFDSKQEIILSFIAYGGEGLYYFVEQFVWLAKSGLIDSKHSKSLGKISAWAEFVGYIGSISLKFRDLKKLSEDEVCLESSVEIAVTRGVGRQEEERRLWKLREKKLMKKLSIVQDFADGLMALADIRDGRGQFSGPLLVSCAGLLSALISTHKNWVSC
The following text describes a protein:
Function:
General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress.
Subcellular Localization:
Nucleus.
Sequence:
MSRASMRCPGCGSSNIVDDDLYCQAQLVCADCGSVVSEGSLAEESFNGPDISYSRTTAVTRKPCVNLIQGLERVKEISRILRVRREIEELALTYYKQAYEHETFLHVTLQRKEILGGCCVLASCRQQRWPITVGTISCLLNGDPAAVGEVYQEMIKVLNIQAPTFSVTDVMEAHCQEYKVSPGHVPEELAEDSKGLTKRAIALVELAADSWIVTGRQPLPIMMAAVYLAWQSLKPNAQRLKMSLEKFCKLAKVQKSKTAGTRITEMKGMLYKLGKEIPWYKEVLTPDNVVSLVGDVLQHRFSLLRRALKSHELSLLEKCPAGQVNPSSAETSSSSDVSEDAGQTPVKSSVNAEKEKQGRDGDESLKSPSEESNPQTQELTQNWGKRVLFAPPCVVNAKRKRAERPPLHVTGDEEISDSEIESYIRTPQEARDFAMMQEKLFTSNNESS
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSRFFSRGYHYDTASSSEDEELLTSSEEELMSSSEEEVVSDDSFFNDSESESAESDDDSDGKPYGPDWFKKPQFRKGGAPGGSGASRFLKGNADSSDESDDEGKKVVKSARDKLLDELNNTYNKIDAAEMTQDWTTILSEFESATKLLVKAQQQNMGTPNVFVRVVAQVEDLVAETSQAEIKNKIVAKAYNTVKQRVRKIARENEELLAKFRQHPEAFEKDSTVEFGQARDFDASDLTLMGRKVADRSAIVSSPSDFFSALRIVIDSRGKKGTDIQAQIKTMEELVSISKSPYESIIAYLNLIPIRFDACANLAYQPLEQWKASHNNVTSLLELLEANIESYHVTELAPRNEFIEEEPQPNENGVRMILGSVFTFVERLDDEFNKSLLNTDPHSSDYLDRLRDEQSVYNLILRSQLYLEKVLPEDTASKHLCRSFVRRLDHIYYKTSKLVDIVERAAWASVPANSSSKYITYSDDPDYNFKLVNTLCTVVSSEQEMLKRRATLYQIYYYALNNQFSKAKEMLVQSNVRNSINSQDPTIQILFNRVVVQLGLAAFKLCLVEDCHQILNEVSTASHLRDIMGQQSLQRVSNNISSNGTVTPTEMLCLPFHQHINLDLIDAVFMTCSLLIEIPHMAAFYSGIKVKRIPYSQKSIRRALEHYEKSSFQGPPETLRDHVIHAAKAMQRGNWAQCINYLRSISTWTLLGDKMEKVLEQLAERIQIESLKTYIFTYKRFYTKLSVQKLSELFSLPTEQVISVIQTLENTINIKGSLNEAKEMLIFDKGDEITKLEEVAIKLTKETKYQSERLNNVSQRQ
The following text describes a protein:
Function:
General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
Subcellular Localization:
Golgi apparatus. Membrane; Single-pass membrane protein. Mitochondrion.
Sequence:
MGDNGVNVVLVMAYGSLIFLLLFVFVKRQVMRLAMKSRRGPHAPIGHNVPKKWKQEIEAKLTQVQKIHFEPRLLSPGDDRLNQPASYDYLYRMKALDAIRDTDFPFRELGGASTAVTGKSFRTWLLNIRNSHCMFRDRQSTLIDTVLDGYTKARHGAEAFGEEEFLKYQEALVELASIVKSGGSSTASQLHQSAAADLSSPSEPPGASVSPDQTAYLTSSLQQRSKKPRHFLELKNFKDNYNTLDNIA
The following text describes a protein:
Function:
Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.
Subcellular Localization:
Nucleus.
Sequence:
MGLNDTRTLPPSAAEQREPSGIAALADATVSPHGLKRALGEYAPRADPCDKKLKRDGDEEDAAVTTSEEAEADADVAVIRRQRRPAVRSSSRSAALSPLNAASAEQIRQHLRDVRRELFLRPLLAVVSKLTFHKANHGFFNVRVDPVVWNIPHYLEVVKHPMDLALVKNKCLNLEYATADECADDIRLVFSNACLFNPPGHVVHEAAAMLLKEFEADYAKYKGKAEAMAKRRDEHSCPFCLDNVCGICNEKCINFEPPFVMCSGACRQRIKRHAVYYKTRDGQYHWCSKCYASLPKTLTLKAAPCSTDHTMPAATEYTISKLGLLKAKFLDELTEPWVQCDQCNGWVHQICALFNACENADEEEEVLYTCPLCRVKELDAEQKDEELGMSPIETSVEDFPVKVETDFVRSHSPALKRRPYTKDFTRALGFGEEIEEKVFNYLTQVDLDAVDASTTSGFVKSQDLQSCDLSRFMQKWILQHLAKLGEHDAAQSIVVKVVSSIKISCHVSSVVREHFRSESQEYPQAVDYTSKVIFVFQMINGVEVCIFSMYVQEYDKYCQLPANRNRTYIAYLDSLVYMRPRHVRTSLFHQILISYLASCKANGYEYAHIWACPTTRGGDFIYWCHPSFQKNPGKERLLQWYSSMAKKAKELGVVFACDDLYAREFEQLEGALDSQLPPYFDGDYWPSEAERVAASPPKRGRKEANTASACSAKFRKRVSESVKSARESQFVIALQPMCAACKQLIVNAAYWRVTDVEALDAYYCAKCHGAAAAANPAAAAAAEPISEVSPPNFIEACSNTNRVKEVEMSCPFLDYRTNMLKNCEEHHYQFDSFRRAKYSTMMLVYKISSTQRAA