lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Membrane-bound transcription factor required for the plastid-to-nucleus retrograde signaling. Functions in multiple retrograde pathways. The plastid-to-nucleus signal plays an important role in the coordinated expression of both nuclear- and chloroplast-localized genes that encode photosynthesis-related proteins. In the nucleus, activates ABI4 transcription in a PHD-dependent manner associated with histone modifications. Localized primarily in the chloroplast outer membrane as dormant form and, in response to retrograde signals, is released from the membrane through proteolytic cleavage and its cleaved fragment containing the transcription factor domain is redistributed to the nucleus, where it regulates the expression of particular nuclear genes.
Subcellular Localization:
Plastid, chloroplast outer membrane; Multi-pass membrane protein. Nucleus. Note=Localized primarily in the chloroplast outer membrane as dormant form and, upon specific stimulation, is released from the membrane through proteolytic cleavage, and its cleaved fragment containing the transcription factor domain is redistributed to the nucleus, where it regulates the expression of particular nuclear genes.
Sequence:
MEAKVPRPRGRPRKRQRLEDDNRKLNNRGKKQVLEVEPAVPISLLGCYMLKDFDDNEVFLGKIVSYDTGLYRVIYEDGDCEELESGDLRRLIISDSYLDDELRVRRKKLDKLILKKEEKKKRNSPENKAVELPNQVNGVQARAVTNSEDGDSYSDSESSESGDKRGSDLEIEAPLVPPVDLPPSSGTIGIPEEAVAHLLSVYGFLRSFSFQLYICPFELNDFVGALYFSGPNSLLDAVHVALLRALKGHLERLSSSKSVLASKCLRCIDWSLLDVLTWPVYLVQYFTAMGHASGPQWNIFNKFVVEIEYYSLPIGMKLKILQILCDDIFDVADLRDEIDAREESEIGFDPDRVATGLLENVPRRVHPRFAKTSAYKEKEVTDSSTNESKDLDSRCTNGGSNEVSSDLDGNSDECRICGMDGTLLCCDGCPLAYHSRCIGVVKMYIPDGPWFCPECTINKKGPKIAHGTSLRGAVQFGMDPHGRLFLGTCNHLLVLNISVNGDAVVKYYNVNDISKVVLVLISASSHTLEYVEICKAITQYWDLPEGISLREGEIGLTQAKDREDGKVSEITKSDSANISNRSHTQTVFDLPTSTLGNTNSAVTGGSCGIQGKKLAARVTYLGLSFKPNTYNNHYTNGELAVSAAASLAVLSSEETHEPDLRKYNSAKKAASSNILEQMKAFSLVAPRFFWPSPDKKEITRERCGWCHSCRLTSASRRGCMLNAAVAGATKGAMKIFSGLFPLKNGEGVLSSIAAYILYLEESLRGLIAGPFLSESPRKQWRKQVEEASTCKALKAPLLELEENICSIALSCDWFKQMDDWLIEHSIFQSAPVTLGVPQRRGPGRTKQNTQAEVTAEGSDADSFTWWRGGKLSKVILLKAVLSQPATKKAAWQGGSKKIPGLNYGDASYIPRRSRRSFWKAAVESSKNISQLALQVRYLDMSLRWRELVRPDQNLQNVKGPETDVAIFRNARICDKKLSDNKVSYGVFFGNQKHLPSRVMKNIMEVEKTQDRNEKYWLQEAHVPLYLIKEFEESLHRVQMPSSTKKPSKKLSKLQRKQLKASLMDIFSYIASRRDKMEKCSCASCDHDVLLRDTTTCSSCHGFCHKDCTSMSQHTNGNVEVLVTCKRCYLSKTRVPTNINHRQSTAPQFTINVRHQNAVIPVIKVKPPSQQLSSQKPRENTSGVKQVTPDSSVSKSKQKTLSCGVIWRKKNVEDTGVDFRNQNILLAGRSDKPSLEPVCGICLLPYNPGLTYIHCTKCEKWFHTEAVKLKDSQIPEVVGFKCCKCRRIRSPDCPYMDPKLKEQKQIKRIVFTNQKQRQGNSGLDSDSERMSEQKDSKPSTPLPATPLYPPDDVFIPEDDPLLVSVSKVKQITPSSFDLEWSTTAFAPGPQKLPVRRQVKREDSDAAYPELHPIVKPEAEEQALPVLTEWDLSGELLFDYEDMEFEPQTYFSLTELLTADDSGGGQYQENGDMVVSGNPQFEPTEKEECEDDMGPCQRCLQMDPAPDLLCTVCGLLIHSHCSPWSALPGSSWSCGQCRIRALGSITLGSFGAITQFKSILPDRSTKVDISLAGPFAGAALSVSMFAVGLFLSTEPDAANDLVQVPSMLFQGSLLLGLISRATLGYAALHAATVSIHPLVIAGWCGLTTTAFNMLPVGCLDGGRAVQGAFGKNALVTFGLSTYVMLGLRVLGGPLALPWGLYVLICRNT
The following text describes a protein:
Function:
May play a role in the process of early and late gene activation, or possibly in RNA processing, for a defined set of developmentally regulated loci.
Subcellular Localization:
Nucleus. Chromosome. Note=It is associated with the active ecdysone-regulated loci on polytene chromosomes, and on some heat shock-induced puffs. Its distribution pattern follows the changes of puffing patterns in the developmental program, or following heat shock.
Sequence:
MVSVKVNGNPQNRLVNNAKVNGNMAFRGNQNRNRNFGGGNNNYGGPMGANRMGGMNMSPWESQNPGGGQFGNNMRQGGGQMNAQAINLANNLLNNLFRNQNPPSLLDLPRGGGGMGNRNQRGGPMVSRGGGAGNRLNNRRGQGGGFQNRGATGSGPKPPPKQGGGGIRKQNAFDRAKKLLAKNANQNKKKEPTPGEKKIESPTKESPYASVPNDMFYCHLCKKHMWDANSFENHIKGRTHLMMREGIEESYRLKANMIRQEAKIAEQLKSIEFDRLKRMGKSKQRQLDYCTMCDLNFHGHISTHRKSEGHLQLKKFLHPKCIECNKEFATRIDYDTHLLSAEHLKKAAENNTKVGERKRQTLPISTEEEETRDLRLPQKRKKKPVKKEGEAADGEAKKEGAGDGEGAEGDEAEGEEAKEGEEAADETKEGDELNESQEEEEVALPVDPEDCILDFNDGDEIPSEVDTRLPKYNWQRAVGPGLISKLECYECSVCSKFFDTEVTAEIHSRTATHHRNFLKFINEKSSDTKIAQKRAAAALEENERKKRKVEEAEAPAAEGAAEETTEGAEGELYDPSEATGDDEDVEMVDDNAEGEGEGEGDEEAEAEVEEDGAGQDNGEEEMEAQEEEGQEGEQEPEPEPAPVQTPAPAEPAPPAKTPAKTPTKAAAPAAVASPAAAATSADASPSPAKKATPARAAAGAKATPQRQRARGRYNRY
The following text describes a protein:
Function:
Specifically hydrolyzes (di)adenosine polyphosphates but not ATP or diadenosine triphosphate, generating ATP as the product. Diadenosine hexaphosphate (Ap6A) is the preferred substrate and hydrolysis yields 2 ATP. It is the only enzyme that symmetrically hydrolyzes Ap6A. It also hydrolyzes diadenosine pentaphosphate (Ap5A), diadenosine tetraphosphate (Ap4A) and adenosine tetraphosphate (p4A).
Sequence:
MELGAGGVVFNAKREVLLLRDRMGFWVFPKGHPEPGESLEEAAVREVWEETGVRAEVLLPLYPTRYVNPKGVEREVHWFLMRGEGAPRLEEGMTGAGWFSPEEARALLAFPEDLGLLEVALERLPL
The following text describes a protein:
Function:
Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes (By similarity).
Miscellaneous:
MISCELLANEOUS: Does not bind zinc ions. Has normal enzyme activity in the absence of zinc ions.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MPKPADHRNHAAVSTSVLSALFLGAGAALLSACSSPQHASTVPGTTPSIWTGSPAPSGLSGHDEESPGAQSLTSTLTAPDGTKVATAKFEFANGYATVTIATTGVGKLTPGFHGLHIHQVGKCEPNSVAPTGGAPGNFLSAGGHYHVPGHTGTPASGDLASLQVRGDGSAMLVTTTDAFTMDDLLSGAKTAIIIHAGADNFANIPPERYVQVNGTPGPDETTLTTGDAGKRVACGVIGSG
The following text describes a protein:
Function:
Provides the (R)-glutamate required for cell wall biosynthesis.
Sequence:
MPPVSFAAASDPAPRSALPIGVFDSGAGGLSVLAELQRALPQEDVLYLADTAHVPYGARSDEDIRDLTARAVAELVRRGVKAVVVACNTASAFSLTHLRERFELPIIGLVPAVKPAVAATKSGVVGVLATPGTLRGTLLADVIRQWAEPAGVRVMQAVSTELVPLVEAGKADSPEARVVLRDVLEPLAEAGADQLVLGCTHYPFLAGSIRAEFGDTFALVDSGAAVARHTRNVLSRGGLLRGGDRTGEVSYLTTSDPAHLRALLMTLRPGGADGASLPDPPSPRIELTTT
The following text describes a protein:
Function:
Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems. Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.
Sequence:
MGQHDIQEFCLKWNNHHSTLVSVLDSLLVRESLVDVVLAAEGQSIKVHRLVLFACSQYFTDLLSQQTDKHAVVFLKDVAFSDLKSLVDFMYRGEVNISQYQLESFLQTAEALQIKGLADKPNQRKYMSSLVLKKPKTSENHAAADTTHQTESQSNVPCPPRLHRSKTATKKTKTLAEKKQSPQQPVESDEAPDLLDCEMDTDPTSGEQLEQEDQEGQSDQESLKDEDDEGWSAGNSQHSLSGISASGSYGAMASAHETGNETWASENGAGASETNYDLTMSDSSQYGEGGATEPVILEDTDGGDRPFSCPRCGRRYKRKNNAVAHLRYECGVVPSFPCPICSHMLSQRRYIQKHIRRKHPDYIQDYQEYKEQRARTSGDDVD
The following text describes a protein:
Function:
Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homomer poly-beta-1,6-N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MINRIVSFFILCLVLCIPLCVAYFHSGELMMRFVFFWPFFMSIMWIVGGVYFWVYRERHWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRYENIEVIAVNDGSTDKTRAILDRMAAQIPHLRVIHLAQNQGKAIALKTGAAAAKSEYLVCIDGDALLDRDAAAYIVEPMLYNPRVGAVTGNPRIRTRSTLVGKIQVGEYSSIIGLIKRTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWTIFYEPRALCWILMPETLKGLWKQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYCLTTIWAFTCLVGFIIYAVQLAGVPLNIELTHIAATHTAGILLCTLCLLQFIVSLMIENRYEHNLTSSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRARWVSPDRGILRG
The following text describes a protein:
Function:
Probable GTP-binding protein that may be involved in cell development.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MEQIITGEGQIVPDLDEHITRSGIDQAGTDYHMVSIIGCQSSGKSTLLNLLFGTKFETMNEQKGRQQTTKGIHAARAVNGPILLFDVEGSDSRERGDSDALFERKSSLFALALSELLVINMWESDIGRYNAANIPMLKTVMEVNVQLFLAQSTSKSKILFVIRDSTIPNFDVIKFQINRDMENIWAEITLPDSLKDKTIHDFFDFDFYAIHHMVIQRDIFDKDISALRQRFIDEKEENYLFKEKSTKVVPGGGLSTYIRNLWEVINENKELNIPSQKLMLSRFKCEENAKAAYDQFKEKVTKTILEPMADESVNLGDKFKSNAEEAIKAANKFYHDNSWRYQQAAVEEFQQKLSTDIGDLLISYYIKHCNYYARQVMQEFTKFISGLPDSFEKGGKWAIEVQAKIDELSLRLDSTCRDSLIEGYKWQFPSFKTIKAMDDARKSYEEIMTKKLYKNIFAEEKIAFDDKASELLMIADQNMWENLRKLIEASAKVTDDRFMEIIKTNVLNPKPQEGTLKRFQRHALNIVKESANYIMMKMKTAFDRSFRYEKNGRPRVWTRRHNLNQIYEESRASGRKVLILFTYCRLASPDDQTPNNPLNQVLIPVEKSQEIEEKFEKLIIHAYEEARASVLASQNNEHIPPWAWFLFLFSCSDYILWWLSNPLLFSLTVLFGGTYLVLNQLGLWDTAVQKLLDIIKKKIVELGATPDENNETETNQTIPVEESQITPPPPTETTTDDGPVMKRRVHRSKAQGLTKTESNVTFANVSNANDEQSLTKNNTEDSLNTGSSSSGQRHRKRVRVGTLV
The following text describes a protein:
Function:
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MTVDEQVRIIVLNDGDHLEAVVRRFEQGWRVYFVLGDNLLGKSVVLKTSLSPHPLPWSNHGSALNAKAEVDCSTAGSFSYEFYVDGSPTRNGCGYFLVDPSLSINGSPLPLDSVVGQTHLAKLLGPLSEWKDRLRVSKESGYNMIHLTPIHSLGISNSSYSIKSHHELNETLNEKDRSVSFDEVTSLVNEMEKEWEMLTVQDVVWNHAAKNAPWLQEHPESAYNCENSPHLRPAYIVDRALHHFGREIGEGKWSDRGIPVCVDREEHIGSIAHSLRHSILPSLRLAEFFQCDVERSVHEFERIAKGGPSSDSLDEVLPLVQDEQYRRRGCTVDMQRTARIFNRTRGDASDESHRVHLCTESFRGHLLHLNGEGERKAQSIIDDIVGACCGHIRYERVDGGGPRKGIVTEKEPLLTDYFLHEFEEGNGWEEEEKNAFDEKRAKFLMAFNGWVMSHDPLKNFALSDSEVYLRRQLVCWGDSVKLNYGDRPDDSSFLWRYMQEYTEKCARIFHGVRIDNAHGTPIHVAEYLLAAARKIRPNLFVFAELFTGSEQLDNLFVNRLGITSLIREAQAAHDSHEQGRLVYRYGGDVVGAMVQKRIRLSAPSVAHAFFLDQSHDNPSPVQIRSVHDLLPTAAMITMASCAVGSTRGYDEVVPHAIHVVDETRLYARWAEGETNEESGLIGARRVLNQLHAKLAKEGFDQVFVDQMSPDVVGITRHNAVTHESVVVVSHTAFNKDAIDRDGRVNLRWIPICGVLEEILFEMEVKEERVEEKEDAERLLGWKSYRVETREHLSPCDDLFEMWRWREYGNMAVGALVRTMQPTSMRLRVTWLGSTTLDAALAPLTLQDMNAVLFKCEGEERESTEGRGGYHIPKHGTPVYCGLQGLIPILHHIRLNNDLGHPLCGNLRDGCWLVDYVHQRMRRYERLTELADKTSSLFAPLYSIPFFLRPAYFEALYAYLYRRVKVATLEKMDSSLLSADSLEQSLALSSVSLSGHVPNAGLPPLSDKIKMKDVFPSSLSAGSPHFSTGIWRNWGRDTFIAIFGCYLALRRYEDAKATILAYAGTLRHGLIPNLLAEGKSPRYNCRDAVWFWLYAVVRYVREAPGGVEILKAPVRRLYPLDSSSFGDGSEREEELRETMREAVERHWKGIEFRERNSGRGIDEHMRERGFDVSIRVDRETGLMHGGNEFNCGTWMDKMGSSEKAGNKGLPATPRDGAPVELQGLAYTVLSEMQKWSEKGVIEGKEIEGGDASISYDEWAKLIEKSFEREFYVDEETQGPHVNRRRILKDTVGSSAGYTDFQLRCNFPIALAVAPRLVSPIKAWAALDTARDALMGPLGMKTLDPSDWAYHGDYNNDDDGCDRATAKGWNYHQGPEWLWVAAYYLQARLAVAKELGGEKMEEARREVLSRLGAYRIALNRSPWRSLPELTNADGKHCAHSCEAQAWSVGCLLEVCQTLRGWSIPQRSNVGGESDEDEEEEGDNVIPRIMARPRFVFTRYLDAHSERKR
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MIKSESCFVINILLLITIMFLLDGVNCRSFLTLRPPIEDDVTPKIVTRKMITVDVKGSEKFTSIQDAIDSVPDGNQDWVLIHVKKGTYREKVRIPREKGHIFLRGSGRTKTVIVWSQSCENNYESSTFKVDADDFIAFGISFKNDAPTGIANTSHNQSVAAYVGGDKAAFYSCGFYSSHNTLLDNEGRHYYDRCYIQGAIDIIFGQARSVFHECEIFVIADQRIEIQGSVTAHTRTSANENTGFVFLKGRIYGIGHAFLGRPKGDHSRVVFAKTYLSKSIIPQGWSDWNHHGSLEHVYHAEYNCHGPGSSTAGRAPWLKKLSGQEAAPFLSTDFIDGKQWLLA
The following text describes a protein:
Function:
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, perinuclear region.
Sequence:
MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGTKTKEGVVQSVTSVAEKTKEQANAVSGAVVASVNTVATKAVEEVENVALTAGVVRKEDLEQPAPPQEDKAAKAEEEVAEEAKSGGD
The following text describes a protein:
Function:
Plays a role in cytoplasmic trafficking of RNA. Binds to the cis-acting response element, A2RE. May be involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMTDSQTKRSRGFGFVTYSCVTEVDAAMCAPPHKVDGRVVEPKRAVSREDSVKPGAHLTVKNIFVGGIKENTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFNDHDTADKIFVQKYHTINRHNCDVKKALSKQEMQSAGSQRGRGGGSGNFMGHGGNFGSGGGNFGCGGNFGGRGGYGGGGGGRRCSYGGGDVDIMDLEVMVATMAVVLFIVVKGPMVVVDQDMETKVVEDMMVTMKDGMLAVGTMVVVGTIMILEIIVDNSNQIMDP
The following text describes a protein:
Function:
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Sequence:
MALGSSAHWKGPGWAGFLNCARSSPHSLVLWEGEGCVSACCSAMARGPKKHLKRVAAPRHWMLDKLTGVFAPRPSAGPHRLRECLPLAIFLRNRLKYALTGDEVKKICMQRLIKVDGKVRTDVAYPAGFMDVISIDKSGENFRLVYDTKGRFAVHRITPEEAKYKLCKVRKVFVGTKGIPHLVTHDARTIRYPDPLIKVNDTVQISLDSGKITDAIKFDTGNLCMVTGGANLGRIGIITNRERHPGSFDVVHVKDANGNGFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSGCIPIRPGLEC
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSSSSETLEVSGQRGLRMAEKPSSFTQTCSMLCQYLKEKGSFGDLSLDMACNMQQSNGTGTPEMFHQKAPPVNFFPFMENSRNLPATPGDFKSMDLFPQQAGFGSSVPRGDVPKMADSSVKKSVPGEPQKAQMTIFYGGQVIVFDDFPADKAKEVMLLASKESSHSQAAQASIPAKSNNVFASHLGKNPMNSSSSVPPSANMFPKFGNQVIQEAPKPSPQPIVCDLPIARKASLHRFLEKRKDRINNKAPYQTSSPAAGPAKPAEGKSWLGLAAQPTQ
The following text describes a protein:
Function:
Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA (By similarity). Specifically promotes the endonuclease activity of the MRN complex to clear DNA ends containing protein adducts: recruited to DSBs by nbn following phosphorylation, and promotes the endonuclease of mre11 to clear protein-DNA adducts and generate clean double-strand break ends (By similarity). The MRN complex and rbbp8/CtIP are also required for chromosome alignment during metaphase.
Miscellaneous:
MISCELLANEOUS: Binds one Zn(2+) atom per dimer. Zn(2+)-binding is not required for homotetramerization.
Subcellular Localization:
Nucleus. Chromosome. Note=Associates with sites of DNA damage in S/G2 phase. Recruited to DSBs by the MRE11-RAD50-NBN (MRN) complex following phosphorylation.
Domain:
The damage-recruitment motif is required for DNA binding and translocation to sites of DNA damage.
Sequence:
MSITASTCGSPSSSESLPNGDLFKELWSKLKECHDKDLQELLMKIGKLKKERCLDAQRLEEFYTKNQHLREQQKTLHDTIKVLEDRLRAGLCDRCTVTEEHMRKKQQEFENIRQQNLKLITELMNDKNALQDENKRLSEQLHDMQKNRHRRKSDEENPADTGDGEDGVIPDSPLSTFSLSMVSRMRRKKENKHVRYTEQTQEDALTFDRKISSGTRPQISTQVNMRKGEDVLVAETLELAPLPNKYEVCTEKPVFNLATVVAETLGLDAMEESQSQSVFNQPGITCAPLFHKSEDSSPRQVKVEFTEGSMEGFQTNDDDTEWNRREASPVFGEPVRNIRRGTDMDCSSPPLPVGLSSKLKSHCSRNAPDFSVHAKAEDGALLTRLSHCIETDSVISQCSSNRQDVLRPSPNKSDAQMGKYIFDSEQHKQTGNRYGKRKNAEAEQEESCESSFDKENNIPLKDISGARHSMLDKPLDLSDRFSVLRPQDRSHESSSRTKLTISLVPEKPDTKTILHIDLKENLHQQTRQKKVFVSGLVEHSAFNLHEDNEVTEEDNKPFHDSETEIMCHVPKRKPRAVHRGVQPTSVLQPNLHMVHACLESQGRPPIDNMQWSIDPGADLSQYEMDMTMEDSKSGSPAKPELEDMDYTYVNESCLLKLKMGDPDDSEAESKDQDSFGEMFDKTEYGEYASYIKDKSPSQSISCKERSDIPSIENKKITSEKEHESKGEPYQKQKAFVEPYFQRPERKKPAIDFPHIEVVRNKEERRKMLGHTCKECELYYADLPEEERAKKLASCSRHRFRYIPPSTPENFWEVGFPSTQTCKDRGYIKEELSPCQRPRRRQPYNAIFTSKIKEQKT
The following text describes a protein:
Function:
Catalyzes the oxidation of 2-deoxy-scyllo-inosamine (DOIA) with NAD(+) or NADP(+), forming 3-amino-2,3-dideoxy-scyllo-inosose (amino-DOI).
Sequence:
MSGAVVVEAPGVHRLVPHEPGEPGPGEALVRVHAAGICGSDREVYQGNRPEGYVRYPLTPGHEWSGTVERVGAGVPGSLVGRKVVGEGFRNCQVCDRCHAGETTLCTAGYEETGFTQPGAMAPTLTLPARLLHALPDDADLTAAALLEPAACIAAAALKANARPGERVAVVGTGTLGMFAVQFLRAASPAELLVVGTRGDREALSRQFGATDFRTKDRPLTDDFDVVIETAGSADAARTAAALLRRGGRLVLTGIPAPGAGGLDPTDLVVRQLEVHTVFGAPPDAWAHTVRVFAAGLLDPRPLVTHELPLAEFSEAIELVGSGDPKVGKVLLRPDALP
The following text describes a protein:
Function:
Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.
Sequence:
MSAVFSANLAKQLLELTPKLIRFPLAKVPFSLKAKVLSQLLAQLLAPQAEDGELDFLADKWVAIRVEDLQLYFEVSFNGRWQVRELTDAQVTFSAKSAELLLVAAAKEDPDTLFFQRKLSIEGDTELGLEVKNLLLSIEFASLPAPIRLSVEKLADAIVRLQLEAKPTVILAKSPA
The following text describes a protein:
Function:
GTPase component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. The Pelota-HBS1L complex recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel. Following mRNA extraction from stalled ribosomes by the SKI complex, the Pelota-HBS1L complex promotes recruitment of ABCE1, which drives the disassembly of stalled ribosomes, followed by degradation of damaged mRNAs as part of the NGD pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MARHRNVRGYNYDEDFEEDDLYGQSVEDDYCISPSTAAQFIYSRRDNKAGCPEPLEEEEYGYEDTEHSNCISQQLTEIQKAQLESCLDHMREVLGESVPEKVMVEAVLHSKFDVQQALDSVLSQDNKPNLKTKNEDTVLTGKAPKGLFCSEIFSGVNLTNMVEHTSNSSLPCFSLGGPVVRFESPCNPPNPSDKILFRPKHVSVPWIKTKTLMSSCKSLGQLYLPLSDNNMTLDESFRKQASLPLADSKVDWQSCNECSSCFSSGAEMLKEYPPEKGSCNQLKCEGLQDLKTLLRLKTGDSLDAQDITSIDFQKNSGKDRDSRTRIEPDIVPKVTKMTVSGKKQTTGFEIPGLTVEENGHNAFPPQKGLSSGDANANMGAAEILPKPVLPSQTVQTLEEPTMTPTPVKRSGKAKQQIDVKAELEKRQGGKHLLNLVVIGHVDAGKSTLMGHLLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETKTKVITLMDAPGHKDFIPNMITGAAQADVAILVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEIVNKLGQFLKQAGFKESDVSYIPTSGLGGENLVTRSQSSELTKWYEGKCLLEQIDSFKSPQRSVDKPFRLCVSDVFKDQGSGFCVTGKIDAGYVQVGDRLLAMPPNETCTVKGIALHDEPVDWAAAGDHVSLTLTGMDIIKINVGYIFCCPKEPIKACTRFRARVLIFNIEVPITKGFPVLLHFQTVSEPATIRKLLSVLHKSTGEVTKKKPKCLTKGQNALIELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVAEIKE
The following text describes a protein:
Function:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Subcellular Localization:
Nucleus.
Sequence:
MEGPEHPGSNVRFMAPTGEPGPRIIPEGMVIDGREQQGSAGGEVEDRLNYIKQQQALQRELLHQHFRQQEEQLARQHQAELQQHLHLQKNCYGLGLKLELLRQHFRQQEEDLARQHQSELQTQLHLQKVAVISRRPENMSPMGMRLQALREQQELAQARGKLQEKQSERQKQLLAGKKKENSAMASTEVKEKLQTFILSKKQREAAANSLHQSPSLSMAHWPHGSLGHMPMSGDLAAAAAYKGHPMLGTYGSNADFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRRDGIGGSFKTRKPLSSEHPTVPYNVHALVDLSPTGVDTSSCKSAPGSGPSSPRSSHSNMVIAGNHEESGVQPAVMPGRMVGGNAADFTLYTSPSLPNISLGLANSSSSADTTQTGEKVVQSALSREAELRAMAAARLGQPLTGHMIPTQSGLAHLAMHGGMESELNQSFPPGNPNLLHARMKALEQQGIPPVTVQHLLAGARHGDLSGPASTVAMIATTMSTGVSRPDNQPPNAIPRRLHKPLGRTHSAPLPGTHMHHLQQQVLHPQHYMQALLRQHVVNKQQLGNGDIAKQPRPEPHPEETEEELKEHTQVTVKQEPLDSDEENEEEESCRQLDMNIDGTSTHRPLSRAQSSPATYNSVKSVFTTGVVYDPLMLKHSCSCGNNSYHPEHSGRIQSVWSRLQETGLVNRCERVRSRKATIDELKTCHSEQHVYLYGTNPLHRQKQDSKKLAGGLQKSFKYLPCGGLGVDADTIWNELHSPSALRMAAGCVIELAFKVAQGELKNGFAVVRPPGHHAEVDQAMGFCFFNSIAVTARLLVQRLKLNKVLIVDWDVHHGNGTQQMFYEDGQVLYVSLHRWDSGNFFPGTGAPDECGNGAGLGKNVNISFSGGLEPPMGDAEYMAAFRTVVMPIAVEFSPDLVLVSAGFDTAEGHAPQLGGYKVTPKCFGHMTKQLMSVAGGRVVLALEGGYDLAAICDCSEMCVQALLGDELPPLPKEIIEQPPNKNAVTSLEETIRRQTPHWSSLSRYASTVGYSLYEAYEREKEEADTVSALASLSVASAPGVGMPASANRAEAAEPMEEDGAAA
The following text describes a protein:
Function:
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
Sequence:
MISSNRTDEFPQLKNTVYLDHTGATLPCSSQLDGFSRDMRENLYGNPHSRSSSSSLCTETIDQTRFRILKHFNTTPEKHTVIFTSGCTGALKLLAESFDWSGLKSCHRTIESSSTDSHDGNEVGTKKRGMFCYLQDNHTSVVGMRELAHDKGADCLCLSKDTMEKLCTVNVSSVDKISSHNEINGTVDDSECNLLPNGLFAYPAQSNFCGHKYPLRWVKKVQDGILHHQTGCRGNWYVVLDAAALVSTSPLDLGTCDADFVTISFYKMFGFPTGLGALIVRNDSAGVLVKEYFGGGSVMAYLAKERFSKSRTELAERLEDGTLPFLDIVSLRHGFDALEKLGGGMKSISEHTFLLAKYVCNQLSSWKHYSGQPVCEMYNRSGFDSVDHQGPIVNFNLLRSNGEHAGYAEFERLASLHDIHLRTGCFCNTGACQHYLNISDQDIKDNLDAGHVCGDDMDLINGRPTGSVRISFGYMSNQEDADRFLKFVKNYFVEREHSTTVHSVVESTALVPTEDTGRIERLKPSANSSSSSSSFSSSSSSSSSSSLPPPSSLSPSSSSSSSSSSSSVSSGPQNTPSSWDQTDVSCAETRSSRTTSQGQRTTDEHSITDAPRLSGIYLYPVKSCGAMEVSEWELSEAGLMYDRRWMIVNDGGVYMSQKRIPHLCLIKPSIDLDNKRLMLAYKDKQPFILPLDISRSHINERSLSQGKVCGDRVNTIDCGDEVAAWLTEVIGQRCRLQQQDPEYHRASKLNRNIAKRASNCSLSLANQSQYLLVTASSSASLLSAVKQSSHQESNGNQLSMDDMVSRFRSNLVVEGCGAFDEESWSKIAIGGQEFEVKGCCNRCQMICINQDTAEKGTEPLYTLSAVRSKKIFFGVHLMNGANLKEGVKVRKGDVVRVLARCTSSETTV
The following text describes a protein:
Function:
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Sequence:
MAFDFGESKPSDPTADFLAREREAAGVLSDDADLFGSSNTAGIGASADDFERSATAFPALDDDGLPAASAPSGGGSAGFGFGDLDDQPAPVSISSNQRAVDDEVGKFEHNFPELDDGPSANTNGGSYHDDADDLMSARAAAPSRVIPTSVPASQPSYSYEEPTEEPEAVRQWRETQKDAIAKRDAEDERKKAEAISKAEQDIDNFYAEYNAKKEKNIAANKENEAKFHEERTRELAEGTTWDRVTKMVDLKNSQSKTIARAGPGSSDLTRMKELYLKLRREGERAPGAAGY
The following text describes a protein:
Function:
SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination.
Sequence:
MASWVFCNRCFQPPHRKSSFSLTSCGHVFCDSCILKGKKNECMICEVPCQTVLLSKHISEFQEKHRRRLVTFYREKISQLEESLRKSVLQIKQLQSMRSSQQPAFNTIKNSVSTKPNGYIFLPPNSSLPDRIESMDIDLTSPARKPETAAGPSRISLISPPQDGRMGSASCRGPQHLSLTPSHASTAKAFRVPPLQVPYKELSPLPASQLSSRATQAPSPSISSSWTGPPRQPISISGLLQRQSAGSASPRGMNTEKMSPFLPSTPANLRSVASPWQVCVHR
The following text describes a protein:
Function:
Shows both triacylglycerol (TAG) lipase and ester hydrolase activities. May play a role in TAG homeostasis.
Miscellaneous:
MISCELLANEOUS: Present with 2190 molecules/cell in log phase SD medium.
Subcellular Localization:
Lipid droplet. Membrane; Peripheral membrane protein.
Sequence:
MTVKEYTKSKLPCSILNIKPTVTKSGEDAPLLVWIPGNPGLLYYYQEMLHHLHLKHPDWEILGISHAGMTLNAHSNTPIFSLQDQVDHQVEVINNFSCKNRKIIIMGHSVGAYIVQKVCLSNKLVGSVQKVGLVTPTVMDIHTSEMGIKMTAALRYIPPLAHVVSLFSYIFFYWILSEGFSRFIIDKFMGCGSTGYQAVLSTRIFLTHRQFVRQSLGLAAQEMEEITTNWEFQDRFINYCEENGISIWFLFSSNDHWVSGKTRSHLSDYYKDKVKQERLKIDVTDKIPHSFVVKHAEYAINAFF
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MKPLGAIAASGGFGCRLTQLVELISERGTNGIERYEQTFGGAKGLADKVKSDLDRGISGTEEDLANRAHVFGANKTPDVDAKTLLELMWEAAQDPILLVLGIAAIISLILGIEVEGHADTGWIEGCAILVSIAVVVMVSAINDLQKEKQFRELLEKQSSTQMADVIRNGQQQRVNYQDLVVGDIVLVNAGLILPADGVLFRANNIKCDESALTGESHDIEKTLEENPWLLSGTSVKQGSGAMIITCVGLFSEEGIIQKLITGVGEEESERLLALDKEGDEQEKLERAEEKKSKKRVSCFVESILQAKLERMALQIGYGVTFMSILTLIVLILSFSIQHFGVDNHDYEASVWSEYVEFVTVAIVVLVVGIPEGLPLAVTISLAYSVKKMMNDNNLVRVLASCETMGNATTICSDKTGTLTTNRMTVVKSWMAGRVYDGSTEVKGLPQDLLARLQAGIALNSDRASNYYIDEESGLPVQENNKTECACLKFGDDIAARKYTEIRKDNPVDSYVKVYPFDSATKRMETIVRLPNGKYRMFVKGASEIILKYATAYDAGNESTTPLTAADREGLEQNVIIRFAEQALRVICIAYKDFDDAQDWDQEEALLSDLVISAFVGIQDPVRPEVPDAVTTCRRAGVTVRMVTGDNMITARAIAINCGIITEEEDGDGVVMEGPDFRRRVVRDDGSLDFDEINRIAPKLRVMGRCSPSDKFNLVKGLIKAGEVVAVTGDGTNDGPALSEADVGFSMGIAGTDVARQASDIVITDDNFSSIVKAISWGRNVYDGISKFLVFQLTVNVVAILVAFIGACAIRESPLRAVQLLWVNLIMDVFAALALATEPPTPELLDRAPYGRNKPLLSRIMLRQIFGHSFYQLVVLLLLIFYGDKMFNIQSGRRYDLTEQQKDDQILTQHYSMVFNTFVWMQIFNEINARVVDDNLNMPGMPRIVGNFYRPFRGFFSNPIFVGVIVGTAVVQVLIVEFGGRAIETEPLDADIWGACIGFGAGSLVWNWLEPGAYADLSPDRAAEIEEEQRGTTPELPPAGLDAPTTPKTARVERSNTVSSQRGAEPATSTSVLWSRVGRRVRRHIRVIGAFRTAGQIARLRRRTAQLATHAIGGPEARAPRRASEQASLEQKGHSVATPASAMWRTAVARVRFQLRVVRAFKNGVVNEVANPAINADQAATTTLTLSSNSQARGREDPEQLPQQTLDLPAPLEK