lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively. By regulating cAMP levels during the asexual blood stage and, thus PKA activation, required for merozoite invasion of erythrocytes and for the parasite development immediately following invasion.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=In early schizonts, localizes to the endoplasmic reticulum. Transported to an apical location and then subsequently discharged to the plasma membrane of merozoites within mature schizont.
Sequence:
MGKVEDFEEHNKNSNQDIEKNVGNRRRSNSNTINDQNENINKNKAIVTKKSFIMNLLRNKEKTKVEQNDDNIVENMNERKNSLKDMSLISDNVEKDNKVKKKNSYLKNLNILGKTKSIEFSFPSNILNNARKNIQEIDEESPLTSNSLRTYKEGISEDNRQNQRNADNNSLNWSTSNINTECNSEFSNIEVKVLKTEKSNSVKLKDNIIDIPNDKNKKELQEINIKNTNKDSYKNLYLKVRNSISFNDNIKIDDENKNDKNNIIDNYNNYDDINSSNEITIDGLNHDDNIKKIDNINNFDNKHDDNLQDHHQNHVHHTFRSSRKSLGNIKSNNTNIKLNNDKNFDTNINKRSILEKYFYDIWKRNITIKKEIYSLSSKNPPNPLKSTFADACQNESSEKELLKKIPLKFNDDSIESLYVLNLNNWISSRMIIIGIVMLILSFIIWPLTTWSLKTSTWGRETYIIILFHTLMAINTLILIFFIIIGSTELCKYSECMSYVLFSLMVALWGLWNIAIGLTLEYNPNLSEMPTTTYELEMIYVLTYIYGFLPLVIIDIFFPSRTKYNWIIHLIFIFLNSSSIILVGSAKPDFVPEIYVVFRILAYTTLCIFLYIGSYTSELQIRYVFYNLLVAGYKLDKIESDMKNKTSNKKISTGIEDLINMLKECTKVILELENETDTNFNVHTKTSYCSNILEQCLSTLTKSDNLYNIDYNVLENPENKKFIEAYVSKSKSNFAGEEVPKGVDFKLNKSFSNNDCISTDKVDLDKKQIKKFLKQINISQLTKMIQFIDNKLLSDWDFNCLTYFDESEYPFFDINLSLICTIDHNIPINIIINFLCFVEKQYNNVPYHNTIHATMVTQKFFCLAKKLGIYDDLEYKIKLVMFISGICHDIGHPGYNNLFFVNSLHPLSIIYNDISVLENYHASITFKILQLNQCNILKNFSEKDFRMMRSYIIELILSTDMKHHFEIISKFRIRRENEDFDYIKNSDDLLILTKMIIKSADISHGSVSWSEHYCWCQRVLSEFYTQGDEELKNKMPLSPLCDRTKHNEVCKSQITFLKFVVMPLFEELSHIDNNKFIKSFCLKRLNSNCIMWDTLMKEEKTIEVYDPAAVKLKDKKKKKVDKKKKSYIDLTLFFIKNVSD
The following text describes a protein:
Function:
May be a regulatory protein for the LCT genes.
Sequence:
MIVLPRRLSDEVADRVRALIDEKNLEAGMKLPAERQLAMQLGVSRNSLREALAKLVSEGVLLSRRGGGTFIRWRHDTWSEQNIVQPLKTLMADDPDYSFDILEARYAIEASTAWHAAMRATPGDKEKIQLCFEATLSEDPDIASQADVRFHLAIAEASHNIVLLQTMRGFFDVLQSSVKHSRQRMYLVPPVFSQLTEQHQAVIDAIFAGDADGARKAMMAHLSFVHTTMKRFDEDQARHARITRLPGEHNEHSREKNA
The following text describes a protein:
Function:
Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Cell junction. Note=Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MGARPLTLLRALLLPLLAGAQAAIVFIKEPSSQDALQGRRALLRCEVEAPDPVHVYWLLNGVPVQDTERRFAQGSSLSFAAVDRLQDSGAFQCVARDNVTGEEVRSTNASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDDQSTHTVSSRERNLTLRPASPEHSGLYSCCAHNAFGQACSSQNFTLSVADESFARVVLAPQDVVVARNEEAMFHCQFSAQPPPSLQWVFEDETPITNRSRPPHLRRAVVFANGSLLLTQVRPRNAGVYRCIGQGQRGPPIVLEATLHLAEIEDMLPFEPRVFIAGDEERVTCPAPQGLPTPSVWWEHAGVPLPAHGRVHQKGLELVFVTIAESDTGVYTCHASNLAGQRRQDVNITVATVPTWLRKPQDSQLEEGKPGYLHCLTQATPKPTVIWYRNQMLISEDSRFEVSKNGTLRINSVEVYDGTLYRCVSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTVKWVRADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNEPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLRCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGSYTCIAGNSCNIRHTEAPLLVVDKPVMEDSEGPGSPPPYKMIQTIGLSVGAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPPATNKRHSAGDRMHFPRASLQPITTLGKSEFGEVFLAKAQGVEEGATETLVLVKSLQSRDEQQQLDFRREVEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKNKDEKLKSQPLSTKQKVALCSQVALGMEHLSNNRFVHKDLAARNCLISAQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAVLEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWAPNPKDRPSFSEIASTLGDSPADSKQ
The following text describes a protein:
Function:
Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
Sequence:
MSAQVSLELHHRISQFLFHEASLLDDWKFRDWLAQLDEEIRYTMRTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNCQISETDIPNVFAVRVNYLLYRAQKERDETFYVGTRFDKVRRLEDDNWRLLERDIVLDQAVITSHNLSVLF
The following text describes a protein:
Function:
May be involved in a process influencing telomere capping.
Subcellular Localization:
Cytoplasm.
Sequence:
MGVGQSTELPGHVGTPEHLSHVLAERFATKCFTPLELTHFKDNFFSRAIDQGGLKYWNEKILSDFLGIPDSSDSHCPLDAGPVIFRMVSYLGAFPFQNTLAPSVLTFEAMVKVAVLLTERYGRVLRRGRKDRIKLLFGSLADVGRRNVSTSPDTEDVCRETDDTVKPHVTGFEVDAPANDDYGDEDEDEDDDDLALAALESLDAIDVFKHDSRVDKKVYEARISVATLRRLLMLFLVIAPLKTLEPVTLYTSDLNEARMESIRKEADTILAAFSTEDSDGGISYRSFANITSTALPYLFDPLTPLFEHLLFSKNLDMTKKSRSDATVTDTIEKPSDSPGPSPSTIVLPGGFESSILKPSVVSHLSFFLPSPTSNANLLRGNMRLHPVFSTAVHGSSLTSFSHNVLTWNAGTLLLLEGAVSESSEHGEGMVTLGAYLPQPWKSAPLSHSSTKPSDSSALPCLFELSPKHQLLQGNPSPSVQKPNAPVAYFSTSTGIAIGCQIPPPSRSQLLTPTPLGAGSLTVDTSLESATFYMSSIGHNGVFLPPATTSMSEETVRKQIDIYTMEIWGLVPDPSDTSSSDLSRQSPVELQRAKWEFEAREAERRRNLNLKAGAGDPAAEGARWLLETAGLIGDRPGQRGGSL
The following text describes a protein:
Function:
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity).
Subcellular Localization:
Nucleus, nucleolus. Cytoplasm. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis.
Domain:
The C-terminal region (aa 215-288) represents the dimerization motif.
Sequence:
MAPKKRSSRGTRTNTLRSRKLASFLKDFDREVQVRTKQIESDRQTLLKEVENLYNIEVLRLPKALQVMKWLDYFALGGNRQALEEAATADRDITEINNLTAEAIQTPLKSVKKRKVIEVDEAIKEEEEDEEEEGGGGGGRKSHKNLRSARVKRCPPSKKRTQSIQGRSRSKRLSHDFVTPAMSRLEPSLVKPTPGMTPRFDSRVFKTPGLRTPAAKEQVYNISINGSPLADSKEISLSVPIGGGASLRLLASDLQRVDIAQLNPEALGNIKKLSSRLAQICSSIRTGR
The following text describes a protein:
Function:
Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
Subcellular Localization:
Cytoplasm. Note=Colocalizes with FtsZ at division sites. Localization to the Z ring is dependent on FtsZ and independent of FtsA, ZipA, ZapA or ZapB.
Sequence:
MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFARKMLTPDAFSPAGFCVDDAALYFSFEEKCRDFNLSKEQKAELVLNALVAIRYLKPQMPKSWHFVSHGEMWVPMPGDAACVWLSDTHEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKIMNDRLKPQVNVDSFSLEQAV
The following text describes a protein:
Function:
G-protein coupled receptor which binds to the neurotransmitter dopamine with high affinity leading to the activation of an associated G-protein and downstream signaling pathways. Couples to G-proteins to inhibit adenylate cyclase (AC) activity and cAMP production. Inhibits synaptic vesicle fusion to negatively regulate the release of dopamine at dopaminergic neuron synapses. Antagonizes octopamine signaling in response to food by promoting the dopamine-mediated suppression of crh-1/CREB1 transcription factor activation in cholinergic SIA neurons. This is most likely in association with the G(o)-alpha G-protein subunit goa-1. In association with the G-alpha protein gpa-14, modulates two types of learning behavior: touch habituation and chemosensory associative conditioning. May act partly via tsp-17 to negatively regulate dopamine reuptake transporter dat-1 activity. Plays a role in behavioral plasticity and regulates the decision-making process when conflicting alternatives are present. Promotes male mating behavior by antagonizing acetylcholine signaling to control the protrusions of copulatory spicules from the tail of males during hermaphrodite vulval location. Modulates unc-7 activity at gap junctions to promote inhibitory neuronal signaling transduction between chemosensory and mechanosensory neurons, and thus ensures spicule insertion attempts are confined to the hermaphrodite vulva during copulation; [Isoform a]: G-protein coupled receptor which binds to the neurotransmitter dopamine with high affinity leading to the activation of an associated G-protein and downstream signaling pathways. Couples to G-proteins to inhibit adenylate cyclase (AC) activity and cAMP production.
Miscellaneous:
MISCELLANEOUS: Modulates drug-mediated behavior, such as the response to nicotine and amphetamine. Plays a role in the sensitivity to the drug nicotine and promotes movement towards nicotine sources. Plays a role in promoting amphetamine-induced loss of motility in water, termed swimming-induced paralysis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEAGETWNVSLEWPPPSLDLSTITQTPSTIVGSGIPLNYAGLSLIVIPLITLLGNLLVIISVLRYRALQSAINFLILGLAVADLLVAIIVMPYAVYVYVTNGDWYLGNLMCDIYMASDVCCSTASILLLAVISFDRYRAVSLPIQYSRQSQNVKRVWTLIAVIWLVSLTLASPMVFGVNVRPPDANPYECRFYNAEFSILSSMISFVIPCFLVLFVYIRIIIALKKREKAAKMRREKNTIAHGLTMRPDTGEEQVDEEAAGRIVAGPVVNVMMAALPSMTRRMRQFERHRRAIELAGDEEWEEDELDVMDECCGGDDAGDDDDDYHADNGQGVVEASAPRTTSMLRRIINAASVGTANSTAQSVASASGMPAFFAQNISTTSPSSSSCARTTTTTSAIPKASGDLPLPMLLNEREFGNSSTPRSSLESLSENVNVITNDFVSENCTTFSRRSSYADDSQPTSSQTSSGDGRSYSIKGQKRFRNLSRNYSTKHHRKVVKVNRGNSRNNSRTASITNQSDDALIPAIIRTISRKSPRLFRRDKTDIKKHSMILANPITEPPKEYRRVSMPIHPTNSQTETETISASRDIENLPTTTISRSTTANSAELLGSPDDFEKFPALITETVLEDVLAETREGCFMQPTVSFALTVREMEGNALNNLKGCSVESSRRVSQVDPPLAIQILTRPSLPHLDLQRMDSIGTTCSSKTRADSLRSVDSKGSKKSNRNGIAVKLVKRAIKHEHSLKRKVSKAQRKEKRATKTLGVVVGVFLVCWVPFFVINILNAVCILLNKDSCQVGYDLFFYCTWIGYMNSFMNPIIYTIFNTEFRRAFKSIIFGRNSTRHHFSNKQAHV
The following text describes a protein:
Function:
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
Subcellular Localization:
Cytoplasm.
Sequence:
MPDPATYRPAPGSIPVEPGVYRFRDQHGRVIYVGKAKSLRSRLTSYFADVASLAPRTRQLVTTAAKVEWTVVGTEVEALQLEYTWIKEFDPRFNVRYRDDKSYPVLAVTLGEEFPRLMVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSAGVFKRHRQIDRPCLLGYIDKCSAPCIGRVDAAQHRQIVADFCDFLSGKTDRFARALEQQMNAAAEQLDFERAARLRDDLSALKRAMEKQAVVLGDGTDADVVAFADDELEAAVQVFHVRGGRVRGQRGWIVEKPGEPGDSGIQLVEQFLTQFYGDQAALDDAADESANPVPREVLVPCLPSNAEELASWLSGLRGSRVVLRVPRRGDKRALAETVHRNAEDALQQHKLKRASDFNARSAALQSIQDSLGLADAPLRIECVDVSHVQGTDVVGSLVVFEDGLPRKSDYRHFGIREAAGQGRSDDVACIAEVTRRRFLRHLRDQSDPDLLSPERKSRRFAYPPNLYVVDGGAPQVNAASAVIDELGVTDVAVIGLAKRLEEVWVPSEPDPIIMPRNSEGLYLLQRVRDEAHRFAITYHRSKRSTRMTASALDSVPGLGEHRRKALVTHFGSIARLKEATVDEITAVPGIGVATATAVHDALRPDSSGAAR
The following text describes a protein:
Function:
Involved in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MGKKQTKPINAKSRSESNVVADPRFQSVHSDPRFSRLKRGNFKVKVDERFKSLKEDKDFKTTASVDRYGRPLNQDKATKEIDRLYELENEGSSSSSESSEITDNEEVASASSKSTKSEELTDEESEDEEVYDPARGEGIISTSESSDESDAESETEAQPEISELAGIEPEENIPRGSETNRLAVVNMDWDNLQAVDLFVALSSFCPPGGKLLKVSIYPSEFGKSRMAAEHVQGPPRDIFTPADNQPSSAELHEAQKFGFDNNESDQDEEDALIEEDLGNEFDMVKLRQYQLERLRYYYAVVECDSVRTAKVIYETCDGAEYETSANIYDLRFIPDDVTFDDDESREVCTKAPEKYEPRDFVTDALQHSKVKLSWDAEDPHRKDLIKKAFTSQDIEDLDFSAYIASSESEDEDVDVIRSRYQKLLSGDADDFQANSNPFEDDDKLEGANGEMEVTFTSGFDVDNNANSSEKDETTIEKYKRKAAERKQRRKELRQLKKTKDDEGEGSDVDLGFDDPFFKDKDASRNNKKNKKGKHTQIEDPTAASKEELENLVREDENDSEQLDHFDMKSILKAEKFKKNRKLKKKASNLEGLQEGFEADVSDPRFAALYTNHNFALDPTNPHFKRTKTVEKIMDESRKRRSNQLEQTQDGKPELKIKKRKAEKGDQRQELDRIVKSIKRSGK
The following text describes a protein:
Function:
Required for heterochromatin silencing within pericentromeric repeats and at telomers. Facilitates the recruitment of Clr6 histone deacetylase (HDAC) by interacting with histones. Also interacts with Rad25, which mediates heterochromatin silencing in DNA repeats by recruiting the RITS complex. Together with Rad25, forms a regulatory hub that defines heterochromatin silencing within tandem repeats via linking RNAi and HDAC.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEETVNKILRAQETRAQLYKELEDALNANQEKKIGLEQMGIIVQLVTEGLNEVSSDIRNYQASLTKELKLLVDSLQEKERSKLQATVKLEQLKVVSTNSPVENTQISELEARLSSLSKEINDILQNMKDEI
The following text describes a protein:
Function:
Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
Sequence:
MPTHLVWFRRDLRLQDNLALAAACRDASARVLALYISTPAQWQAHDMAPRQAAFISAQLNALQTALAEKGIPLLFHEVADFNASIETVKNVCRQHDVSHLFYNYQYEFNERQRDAAVEKTLPSVICEGFDDSVILAPGAVMTGNHEMYKVFTPFKNAWLKRLKEDIPPCVPAPKIRVSGALSTPLTPVSLNYPQQAFDAALFPVEENAVIAQLRQFCAQGADEYALRRDFPAVDGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGPGSVWLNELIWREFYRHLMTWYPALCKHQPFIRWTKRVAWQENPHYFQAWQKGETGYPIVDAAMRQLNATGWMHNRLRMITASFLVKDLLIDWRLGERYFMSQLIDGDLAANNGGWQWAASTGTDAAPYFRIFNPTTQGERFDRDGEFIRQWLPALRDIPGKAIHEPWRWAEKAGVVLDYPRPIVEHKQARIATLSAYEAARKGA
The following text describes a protein:
Function:
Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.
Sequence:
KIMPACDWTALVVTCKTKDYADAIQAQLEMRQKLGELSKDLMILCIEDPQEGLGSGGATLNALLVVTELLSAKNNYTVVTSDVLKGAKILILHFGRYFPYNPLGRGFVSLALNPEVGESDCLMTNFDALFKTVSTNLAHNSPPGLWVCSSDMLISFPHNYAINWDSVNINDGAVCISVPSTKQYASYHGVYKIGADNKVEDLIFRGDDAQISACTLNSTDDLVPLTTGIVFFSTFATERLLTTHNTPPLDACTYMGIDSGMDPLCLSLFFDILLPLATDVNEKEFIKGQRSGAFGQEDKKPLGKDKQLMRNARSVLWKHLRDLPLTAVHIDVGSHCYLDMSEPPSKYCDVLLNQCPEISGFKPSKQVHSYVHSNSVIGDKVLLINSIIDSGVTVGSNTTIIHSHITENMIIGKNCYLCGIDKQSSFVVPNSNIPSNSSIIGTYVNLPTTARVFVSMHSQGKLLSDNDNVEDVTINSMGEIISTQSNVIKPEVEHAKLLPFSYRNVLAKAKLVPMLHSNQAVNISDSMVLLKKHISKTEYEKWLSSVRCSFCEVLENVNHMKEFKYGMNMYFDVACKKVSEILMQNHDISLLPFFKMFTVNGEHGRVLELLDQIAIDSKRPDISARAFACIADVLGFMAGAKGGLRSGPASNKQWKQPLHYLEEGRIEEGVRALANIRKSWINHPDQLTRAARHYEGAEQILIRHAVMSVSSFVKLVPSVQAQSNTWYIAECPARIDLSGGWTDTPPVCYEHGGAVVNAAILLDGKRPIGARIRKLDTPVVLLTLLGQDDSSTQIIECTSKEQFLDYYQPQAPAALLKACFILAKIIDLESDVSLENHLKDEFGGGFELQTWSMLPRGSGLGTSSILAGAVMSVLYRAAGYSADADAIIHSVLLVEQMLTTGGGWQDQVGGCIGGVKIGRSEKILPLRVTVEMLVLTDEQAEKFNKHLKLVYTGKTRLARNLLQNVLRNWYARRTEILDICKGLKENAEDCAVAFNEGSIERVGKCVEAYWKQKKMMATGCEPEVCARMMEALRPYCYGQSLCGAGGGGFMYVLMKEEHPNDFIRDILKNIKGAQDAVVYNVEIDRLGMHLQYLMHTTTHNWYAGPTHVTTT
The following text describes a protein:
Function:
Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNPAAGMFPMFPPPPPPEMPFSYHTFPAPPPPFYFHNAAPVPVVCSVWASNFRDESHNLRRMAWNARYVAVNVQYPGLVHHHAGKDHNVLTVEERYSVVKANVDTLKPLQVGVALRDADGRHLGAWEFNLRDFCRLADPCDGNSLKYLDDRGLNVDELRVRGLSAKMLREALLCSGLLDARGGRSWIVYAGAYHVSYLLKLLTGGAPLPEDMAGFVDAVRSYLGDQVYDVARMAADCPAMPLGLERITAHLGFQSPLGSPCLAAAAGVHALQVFMRLKYGELGGDVERHQGLLQGLH
The following text describes a protein:
Function:
Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity.
Subcellular Localization:
Secreted.
Sequence:
MQTGSTLERLRPNPAPGAGVSRPSFCPGLPPRGLGRAPGSSQGPGKVDAFREEARQGLRRAWWSRPPAPGLAVPMLAPRPLLLLLLLVLGPTSGASLPPGPRSHPGVCPNQLSPNLWVDAQSTCERECVGDQDCAAAEKCCTNVCGLQSCVAARFPDGGPTAPAPPASCEGFTCPQQGSDCDIWDGQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLRLRVVPCKHVLSWPPSSPGPPETTARPPPGAAPVPPALYSSPAPQAVFEGGTASLHCDVSGRPPPAVTWEKQSDQRETLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVRRDAARDTAPTPSAPAECLPDPRACAGAPSGLVLWHFDPQRGGCMTFPVCGCDGGGRGFETYEACQQACARGPGDACVLPAVQGRCQGREARWAYSPLLQQCHPFVYGGCEGNGNNFESRASCEDACPVPRTPPCRACRLRSKLALSLCRSDFAIVGRLTEVLEEPDMGGGGIARVALDEVLKDDKMGLRFLGTKYLEVTLSGMDWTCPCPNVTAGDGLLVIMGEVRDGVAVLDAGSYIRAASEKRIKKISELLEKKACELLNRFQD
The following text describes a protein:
Function:
DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs.
Subcellular Localization:
Nucleus.
Sequence:
SLFDASLSRSATASGGIDFNRLREKRRVAHAVNPAAEAMRKQLEFKKQSLTNMAATINNGKVAPIFNKAKPKNGTIIKKAKREDSVDDFLDDEEEEEEFMSESEGEMEDLGLSDDEVRKRKKPANGVVKKTPPQPPKSKTLSDFSEEEVDEGAFPKASPTLKAAVASPPKPVKKERTLSDDSEEEGGGWMAKPRMMTSKASKKAEPKKPRKKIDVSSSEDEGARYEETDEDEIPAKKNKAVIDSSPDSVPVIKQKKEKKEKKSKKNKGRRGGSHSDEEEVFSGSDGEAARETDSEASDNDAAYSAATRVIHSKMVEESLLSAPRIVERIAEKIMASRPFDGYEALRACISSIPRVSGNAVLDAFQEYLENRGVLEQILDDCRVHSSQVEEPSERAEEGRHVELPLLNPGMTLHGYQQEGVDWLVEMHHKGLNCILADEMGLGKTIQIVAFLSWLKHTHVRGPHLIVVPSSTVENWIAEMKTWCPTLKVITYYGSQEERRDIRHSAKKKKDTVDVLLTTYNMIGSKSDDKKFFKTFSINYVIFDEGHMLKNCGTDRYKSLMKIKTQRKILLTGTPLQNNLIELISLMYFTITKVFNKYCDDVTQLLQHFKQQRPALEGSDGLLYQRDRIEQAKAILQPYILRRVKSQVLSQLPPKSEEVCEVEMEEEQVELYEDVVEGLTKLDTGDTSNGYGGLMRLRQAANHPLLRRKLYEDATVLKIAKMLCAKEKQYAKKKPEHLAEELEGYSDFQLHQLCEKFHCTHKFLLEESLALKSGKLKFLDGKLAEIKQKGDKVLIFSQFTSMLDILEVYLRLRGYTFSRLDGTTPVLDRLEMINAYNEDPGQFVFLLSTRAGGLGINLVSANHIILHDIDFNPYNDKQAEDRCHRMGQKKPVYVTRLISKETIEVEINKLARKKLQLEKDVTEGSRGLKGEEGGDEREETTPPVSGDDLQRMLTEAIQRSPRRKSCSERNGMNGVESSPHKKSPSKSPTKRRNSHSKD
The following text describes a protein:
Function:
Inhibits estrogen-induced cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MLKQILADMYIDPELLAELSEEQKQILFFKMRQEQIRRWQEWEAKCDQNEDKKRNSRPRKACNKSVHWRFGTDQEVWVWVMGEHSSDKPYDQICDEIIAEQARREAEKEAEQLRKKQEVELSQLSTLRLHPHNNADLLKKNTDTKQMVNENVRIANQQIINDENQSIIEKPRTVEDILSAATSKNKYEVKQKKENILKEKENDRLQERTQEIYMNWKEAQEVKQKLEKEDKEWQESLRKSKLADERRRSVAKQARDDYKRLSMQGINRGKVADTAKTFGAVKRPPIPPKPKLPPSANNSSINRMDRRQGIRRLNSAINRENIIKWFKEEQLPLKAGWDKSGSYVEPWFHGIISRQESEQLLGSHGHGSFLLRVSEKIQGYVLSYCSEEGCAHFLIDASATSYSFLGVDQLQHTTLADLVEYHKTEPIPSLGRELLRFPCGQKKGVCDYSDLLE
The following text describes a protein:
Function:
The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.
Sequence:
MSLKKFRFYFALFVGKLIYYSMKILNLDATTFPGKVALKIYPDFLKEISKRIGIRILITGTNGKTTTNNLLNYVIRSKGYKVIGNLEGANLKSGIATSYIKNSGVFDFGTFEVDEGVFPYVYKDLLPQYVVITNFFRDQLDRYGEIDITVNKILNSIKENTTLILNADDPFVARFSRLSNRKIFYGIGVKIREGVEGIKESIYCPFCGRKLNYEFFNYSQLGKYSCECGFKNPEYDFYISSAHLNGIWTIEISEKSKKYDLTFKYPGVYNLYNVLSAYSILRFLNFDPLETSNIISKFEFKLGRLERFIYRGFDRIIVLVKNPAGYNQVLDTIKDDKEEKVLLLILNDNIADGRDVSWIWDVDFEKINDLKGIQKIIVSGTRGEDLLVRLKYAEIPREKLQLEENLKKAIDYSISFPCKTYILPTYTALFKSRKILIGKVKDGA
The following text describes a protein:
Function:
Plays an essential role in chain termination during de novo fatty acid synthesis.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MVATAATASLFPVSSPQPNGAKTSGKHGGVPDNLDVRGIKTKSVNSGSNGMQVKANAQAPTEVNGSRVRLMNGIKNDDNLTSHAPRTFINQLPDWSMLLAAITTIFLAAEKQWMMLEWKTKRPDMLADLDPFGLGRIVQDGLVFRQNFSIRSYEIGADRTASIETLMNHFQETALNHVKTAGLLGDGFGSTPEMCKKNLFWVVTKMQVMVDRYPTWGDVVQVDTWVAPSGKNGMRRDWLLRDWKTGEILTRASSNWVMMNKETRKLSKIPDEVRGEIEHYFVDAPPVVEDDNVKLPKLEEAKADYVRTGLTPRWSDLDVNQHVNNVKYIGWILESAPKEVVEKYELASMTLEYRRECRKDSELKSLTSVLGNGNGIGDSGSGHVDCQHVLQFQGGGGGEIVKGRTGWRPRYENQIKGIDVFSGGKA
The following text describes a protein:
Function:
Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development.
Subcellular Localization:
Nucleus.
Sequence:
MLIPSSSSIPSSLSASASDSEPSSLNGSGISDQNILPNYHLHHHLINENEMEAANYAQVIKPTCEAFQDWPHTPMLYQQPQLHFMLPQHDWAYPHLAQSLPPPHHLTPSTAAVAAATIASQSSIINQTSVVTSTPSCQIKQEVERPEIIQRLMPPWPPAYQFSCDDSGSVSGAGGPHQPLSDISDDSEQTCPDDLEGFAKQFKQRRIKLGYTQADVGVALGTLYGNIFSQTTICRFEALQLSFKNMCKLKPLLFKWLEEADSTTGSPNSTFEKMTGQAGRKRKKRTSIEVNVKSRLEFHFQSNQKPNAQEITQVAMELQLEKEVVRVWFCNRRQKEKRIAPNQYDAPHPMALNNGYPMTADLFPYQAVVNHYTQQSPRQQ
The following text describes a protein:
Function:
Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization. May be involved in the regulation of food intake and body weight.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Sequence:
MESSPIPQSSGNSSTLGRVPQTPGPSTASGVPEVGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSSALFDHALFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVTWEEGAPSVPPGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAPQTTPHRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPISTGQVESVVTWIGYFCFTSNPFFYGCLNRQIRGELSKQFVCFFKPAPEEELRLPSREGSIEENFLQFLQGTGCASESWVSRPLPSPKQEPPAVDFRIPGQIAEETSEFLEQQLTSDIIMSDSYLRPAPSPRLES
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MGNSSSSNNKHNNENILNLNNINSNNNNNNNNNNNNNGSNTIGSKILTIEEIQHLFREDNKNLISAEDINNSIITLKNNLYSGSVNIHSILAKIECIFYASSTSNYESTIEYFKSLSKPICCSKVWGPKTMFYRCKTCAKSPNSSICFECFKAGPHEKDGHDYSMSFASYGGSCDCGSIDSWKEGGFCDQHKHPEEDHIPTKDMNKLHLVSTHLVFRHLLTIVLDLNKQPLGSLLERPVFVSVQILKWITEMAHLCRSVSHVLSEELCYQSLDPAIISPKETIPKSIPPIIIKPVLFTDQDYQIQLLKTENILNNNLSNTTSKTTTTTTTTTLTSNVNLLSRSLSELTIKSINDRLFKFSYPISYDYRPPLYNLLNISDEGIKQEYMNLFLFLLCEHTFKFGFSQSYLKVYKSLCYNNTVDILFRFSPQIFSVCSVSEQFSIDRENGFIDCIFESLFFHLSDNKKLDKNHIAIVSDLKTILQHKSIAHHMMFTNRKYLELYIRLLQTIQSTSDDRYGDYQKRYIDTHIPYEDTQWIQFFQIDTEFKEISYILIDSLSEEDSIEGLKDMIQFICDRLILDPELEGMTKYNGVSVTKKDLFRGEKSVTTTLPYHRFLGVAINRVKQLYPKEDLRDIVPQTFNFSAFIYQFVLANVYCQQVNSNYWVRNGDVAIKKKAYVYSLFFLELDLSILQLSASIVDIDEFLIFSSKEFGATIPYRITTEENGNFHRYGHFLKFVIQILQERLFFMSTDEHTKYTLVQLLSSKPKTHSQIDSVMNYVERELNYEHILREISDEIHSNSDSPYHYKMKNEFWKNFNLYYPLFTPYILGEESLQSFLEYKKKNNIEFPESLPCPPIIECSKDKVVPKDRFNFSQIIHSDYLFYMFNSIITSYLNENEENNEVGCGINDVLFLILLILEKTQKLVDPLDSNVDLDWKLFDTYSPAVKHHDSIKCILQTTFGNKSILTNLIEMYNQSINNSLHQDKIEYIEKSLKILASIHPSILNRICIKCPSLEEKLRLTKNTGSSSVSGPLSPNPNSDKKMDAKKRQAEIMAKFAQQQSKFLESANDMDFDSDEDDYEDHKIHSTSKNKKQNPFSSPQTKNTTTTSSPSPSKGSNNMLSPQFKNSTPQINGSRELFNETLKSKDCVLCRETHSSDLDPLSLISFLQPSRMIALAKSSYVAKKSPELKRYDTFSRDSMFYNFPQKRDMNTLNFMSSFHIRSCGHYIHKKCHKKYFPKVLNHENEETNFKPSLKEFLCPLCRRIGNIIIPTYTESSVTCSPIISGFDLSNLNSKYNLYQSPTQQHGNDTLTNSNSSDGISNNNNNNINNNNSLNNSSSTSFSNIGGSSSALNGNRLIEAWIDGLKKRLKDIRFIEPRGELFFSTAVNDLMIPLIEGVTGMVYFQMVAKNIELLELASRPYSKKGHPNENLYPITNDLFNRDMLTIHTLFNLVSILAHNAIDTKFKERLVEILKGKSSSILSIDPFALFIVLTIVLGSPTQQDIEIITNLILNLFITQFYLTNLYTEKEINKKSGNKKSISILFNQSYNPSNGFLKDKFREKLEISLEPLLKCIFIAVQFIYPSALGGSSSIKLNGSKLDNGSISYISKEDLINREMIFSKLNIPSTDELINQSFSNQYLSSWLTQLESKKVDPFFTVQYTRPEFIELPRTYEDFFVSHTNSECYNCKTKPDSSAVCLLCGTLVCIKSECCNALDKGIILGEAYQHTLRCGYYKVGLFIECKSPKVDILRDYRKSSYSNIYLDSYGEPDPQLERGKPLLLNDHNYQDLWNYWVTHSLEDKYLANSSLSSRNF
The following text describes a protein:
Function:
May be involved in floral abscission.
Miscellaneous:
MISCELLANEOUS: IDL3 is only partially redundant with IDA.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MSSRSHRSRKYQLTRTIPILVLLLVLLSCCNGARTTNVFNTSSPPKQKDVVSPPHDHVHHQVQDHKSVQFLGSLPRQFPVPTSGPSRKHNEIGLSSTKT
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of 2-phosphoglycolate.
Sequence:
MKKRTFAVDIDGTITENGGGRIHLDALESLRRLVNMGHDVIFVTGRSSVEGFLLSVFGGTTKVSVGENGGCITLDSNDHILLGNLEECKNALNILKNNMENVEEKYVFPRMTEVVLQRTFDLDQARKILSENNIDVVLSDSQYAYHINSPGIDKGTGFTEIMKKFSISRDDVIAIGDSATDVPLFKVAKTSVALGNASDDVKSEATMTVSAHAGDGVLEALDKLAPILSEI