lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
Subcellular Localization:
Nucleus.
Sequence:
MQEFHSSKDSLPCPATSWDNSVFTNSNVQGSSSLTDNNTLSLTMEMKQTGFQMQHYDSSSTQSTGGESYSEVASLSEPTNRYGHNIVVTHLSGYKENPENPIGSHSISKVSQDSVVLPIEAASWPLHGNVTPHFNGFLSFPYASQHTVQHPQIRGLVPSRMPLPHNIPENEPIFVNAKQYQAILRRRERRAKLEAQNKLIKVRKPYLHESRHLHALKRVRGSGGRFLNTKKHQESNSSLSPPFLIPPHVFKNSPGKFRQMDISRGGVVSSVSTTSCSDITGNNNDMFQQNPQFRFSGYPSNHHVSVLM
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in flagellum axoneme. Binds to the intra-tubulin interfaces.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MTTTQKHDLFTPEPHYVPGYAGFFPQLRYQVGNTYGRTTGQLLTDPSVQKSPCSVLSPMSKPKFIEDFSQSKPPRVPCQDLTEPYIPHYTSLKPSKNFEILGQLPPLEVDAQEPPGVENIPRQILLPAGFTPDTPHPPCPPGRKGDSRDLGHPVYGEEAWKSATPVCEAPRQHQLYHCQRDEYPPPARRQQETLDVGSFQRLPQLDHPNLIQRKAISGYAGFIPRFTWVMGLNYRDGVMQAMDEFDKSQFLFRNPHCDLGEKLPGTHWPSNHIYSSQGLIPFYMGFIPAMQDNYALTFGNSTRRAYWKEWAKRNHTL
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MSRTLYPSIRSDTGYNTMQQPAQDHNKPTIEMSLREHLLAAGAGQPSTQPLPQHSSPQGPPHAIDPAIAGQAYQMSQGAIDDGNTSEGRSKGRRELSTSKRAAQNRAAQRAFRQRKEEYIKQLKDQVKEFEQLCELYKTLQTENYQLRDYIINLQSRLLETQGEIPPAPAGVDLNRPHGEPANLNPTQPQPPQHPQQSEQQPQPQESSSSNNGGLSERQIGELQMAAQAAAAAQHGPAVGHKHSNSEDSYDYAEKRQKADGSPQGQLSSPPATYPDPNA
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
Subcellular Localization:
Cytoplasm. Nucleus. Nucleus, PML body.
Sequence:
MFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRSEAPNWATQDSGFY
The following text describes a protein:
Function:
RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA (By similarity).
Subcellular Localization:
Nucleus speckle. Cytoplasm. Note=Colocalizes predominantly, with SFRS2 and LUC7L3 splicing factors, in nuclear speckles. Cytoplasmic localization is faint (By similarity).
Domain:
The PWI domain binds nucleic acids with significant help from its N-terminal flanking basic region. It has an equal preference for binding to single- or double-stranded species, and it contributes to RBM25 role in modulation of alternative splicing, maybe by mediating RNA-dependent association with LUC7L3 (By similarity).
Sequence:
MSFPPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPGTPMIPVPMSIMAPAPTVLVPTVSMVGKHLGARKDHPGLKLKENDENCGPTTTVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGASGKLQAFGFCEYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKANGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRERDRDRDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPVEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVPLDYGEDDKNATKGTVNTEEKRKHIKSLIEKIPTAKPELFAYPLDWSIVDSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQSILDDVAMVLDEEAEVFIVKMWRLLIYETEAKKIGLVK
The following text describes a protein:
Function:
Activity is required in presynaptic neurons, in a dose-dependent manner, for normal presynaptic development and morphology. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord.
Subcellular Localization:
Cytoplasm.
Sequence:
MVQEDDENLRNSMSLRPTSLSTRPTSLSVNGNEKTLPEESVLRSLSTGTLKYPDDEHLYTFSSANLQDLGAIGNGNFGTVYKMRHKETGKLIAVKRIRCNNIGHREQIRLLREHDTIVKSEKGPNIVKFYGAIFSEGDCWICMELMDISMDLLYKRVYMVKNSRLNENVVGHITVCTVDALDYLKKELKIIHRDVKPSNILVDGTGAVKLCDFGICGQLEESFAKTHDAGCQPYLAPERITSSDKYDVRSDVWSLGITLYEIATGKFPYQEWNSLFDQIATVVSGDPPILHPDSDDFHYSLPLVKFINTCLTKDRRHRPKYDTLKSFDFYRIYAVAGPEIEEAKRILGVEAIDTRNHPVDHRG
The following text describes a protein:
Function:
Required for initiation of larval growth and normal mitotic growth but is not absolutely required for general biosynthesis or DNA replication. Required for progression of normal oogenesis and maturation of some imaginal tissues into adult structures.
Sequence:
MGGKKKVHPKTRTAAFKASEPSEIVEAPHSFVIHRGLACPYITDLTLDFRRIMEPFTASNLREKRMNRIKDFVSLSSFFHVSHMGIFNKASTQLSFKVVRLPRGPSLTFKVHQFTLARDVISLSKKQMIDNDHFKHAPLVIMNNFSGDGKHLKLMATTFQNMFPSINLATVNIGTIRRCVLFSYNPDTKLVEMRHYSVQVVPVGLKRAVQKIVKGTVPNLGKCNEVVDFVTKDGYASESEAEDDEQSHVVLAQTLKSKGNLEDKKSSIKLHEIGPRLTMQLIKIEEGLLTGEVLYHDHVVKTEDEKETLRKLVEKKRKQKEQRKKEQAENRARNLKLKKDEKWAAKRAAEGRTDSDPEDDAEYYKEEVGEEPDEELFKMEAKSSRKRPSLGGGMKYKNKRAKLDTKDKNDKSERTDKYDRKDKFDRKDKKDKFDPKNRRAKFDPKNKRAKFDHRKSRKSK
The following text describes a protein:
Function:
Putative acid-stable proteinase inhibitor.
Sequence:
MRASSFLIVVVFLIAGMLVVEAAVTGVPVKGQDTVKGRVPFNGQDPVKGQASVKGQDRVKGQGPVKGPVSTKPGSCPNILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMACMVPQ
The following text describes a protein:
Function:
Regulator of phosphate homeostasis (By similarity). Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism (By similarity). Negatively regulates osteoblasts differentiation and matrix mineralization (By similarity). Up-regulates EGR1 expression in the presence of KL.
Subcellular Localization:
Secreted. Note=Secretion is dependent on O-glycosylation.
Sequence:
MLGTCLRLLVGVLCTVCSLGTARAYPDTSPLLGSNWGSLTHLYTATARTSYHLQIHRDGHVDGTPHQTIYSALMITSEDAGSVVITGAMTRRFLCMDLHGNIFGSLHFSPENCKFRQWTLENGYDVYLSQKHHYLVSLGRAKRIFQPGTNPPPFSQFLARRNEVPLLHFYTVRPRRHTRSAEDPPERDPLNVLKPRPRATPVPVSCSRELPSAEEGGPAASDPLGVLRRGRGDARGGAGGADRCRPFPRFV
The following text describes a protein:
Function:
Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
Miscellaneous:
MISCELLANEOUS: MhuD has the ability to bind 2 heme molecules per monomer but only the monoheme-protein complex is active.
Sequence:
MPVVKINAIEVPAGAGPELEKRFAHRAHAVENSPGFLGFQLLRPVKGEERYFVVTHWESDEAFQAWANGPAIAAHAGHRANPVATGASLLEFEVVLDVGGTGKTA
The following text describes a protein:
Function:
Serine/threonine-protein kinase involved in the spatial and temporal control system organizing cortical activities in mitotic and postmitotic cells. Required for the normal functioning of the plasma membrane in developing pollen. Involved in the regulation of cell expansion and embryo development.
Subcellular Localization:
Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center. Nucleus, nucleolus.
Sequence:
MSRQATSSAFHKSKTLGNKYMLGDEIGKGAYARVYKGLDLENGDFVAIKQVSLENIAQEDLNIIMQEIDLLKNLNHKNIVKYLGSLKTTTHLHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLTEADVNTHSVVGTPYWMAPEVIEMSGVSAASDIWSVGCTVVELLTCVPPYYELQPMPALFRIVQDENPPIPDSLSPDITDFLRQCFKKDARQRPDAKTLLSHPWIRNCKRALQSSLRHSGTIRNLSETVAADGESSTGDNQSAGKTLPVHKAEASETSSRKELLSAEGTNEGKYDHDHSADSNLREERINNLDDDLLSDEVPTLSIHEKSSLRSSSGRLSVKNVVATPGPAQLHEISQQDDDFGSPKSSKKHVEKGLVGEETSVDIGNKSFCFGPTQDAGLQKATKASVTSPGNELSRFSDPPGDASLDDLFHPLDKSLEERVADASTSASALNVNQATVPDAGKNDLAKKLRDTIAKKQMEEEMGQSNGGGDILRLMMGVLKDDVIDIDNLVFEEKLPSENIFPLQAVEFSRLVSSLRPEESEDAVMTACQKLIAIFHQRPEQKIVFVSQHGLLPLMELLDIPRTRVICSVLQLINELVKDNTDFQENACLVGLIPLVMSFAGPDRPREVRMEAAWFLQQLCLSSSLTLQMFIACRGIPVLVGFLEADYAKYREMVHLAIDGMWQVFKLQRSTPRNDFCQIAAKNGILLRLINTLYSLNEATRLAAKSVGGRFSSDGSAQQQRSGPLDSSHPLFSQNEIPLSPTDHLLDRHGMTEHSFPTVTQESSRASTSHSQRSDINLPDPRCLSIDGDRPRSSNGASDISVGSKLAYFTSMEKVANIGTKESSTTSKGRENMDRWKIDPADLRQPKASNSINRTSTDRPPKLIEAMSNGFTTSRTTQAEQVRPLLSLLEKEPPSRRFSCQLEYVRHLPGLEKHESVLPLLHANDRKTNGELDYLMADFAEVSGRGRENGIVDSTPRISHKSASKKVGQLAFYEGAASRSGIASQTTSGVLSGSGVLNARPGSTTSSGLLSNMVSTMNVDVAGEYLEKVADLLLEFAQADTTVKSYMCSQSLLNRLFQMFNRIDPPILLKILKCINYLSTDPNCLENLQRADAIKYLIPNLELKDGPLVSQMQHEVLNALFNLCKINKKRQEQAAENGIVPHLMSFIISDSPLKQHALPLLCDMAHASRNSREQLRVHGGLDVFLSLLDDELWSVTALDALAICLANDSDNQKVEQALLKKDAVHRLVKFFQCCPERHFFHILEPFLKIITKSSRINTTLAVNGLTPLLIARLDHQDAIARLNLLKLIKAVYEHHPRPKQLIVENDLPQKLQTLIEERRDGQRSGGQVLVKQMATSLLKALHINTVL
The following text describes a protein:
Function:
An alpha subtype methylase that recognizes the double-stranded sequence 5'-GATC-3', methylates A-2 on both strands, and protects the DNA from cleavage by the MjaIII endonuclease.
Sequence:
MEVKPFLKWAGGKTQILSQIEENLPKELKEGNIKKYIEPFVGGGAVLFYLLQKYEFKKVIISDINEDLMLCYKVVKNDVDRLIEELSSLRDEFLSLDEEKRKEFYYKVRDDFNKNKNDCDEVKRVAQFIFLNKTCYNGLYRVNKKGEFNVPYGRYKNPKIFDEQNLKNVSKLLKNVKILCGDFEIVDEYVDAESFVYFDPPYKPLNKTSSFTSYTKYDFNDDDQIRLAKFYRKLDKRGAKLMLSNSYNVDFFGKLYEGFNIKKVVAKRMINCKGDKRKDGIYELLIMNY
The following text describes a protein:
Function:
Transcriptional regulator.
Sequence:
MPMGRVSRTAISIPRELMSDLDDLLSQLNLKSRSKAISEAITLYIAERYWVLSDVEKEVAGAIIMVYDHHKESEITEVQHKYLDLIRSTSHVHIDEERCMEVLMVLGSLSRVRELFKELQALGTAEVLKPFLVPRG
The following text describes a protein:
Function:
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.
Subcellular Localization:
Nucleus.
Sequence:
MGKNTDKLYITQSEHSGVHGWHAGMSGIAKRKAASSRPQLPFNYCALSLQPFTHPCCVLDSENVATLFDFRHIVPWIKKHGTNPVTKEPLTVGQLMKLNFTKNATGEYCDPVTMKVFNQYTHIVAIKPTGNCFAYDTIENLNIKPKNWKDLVTDTPFQRSDIITVQELGRLPNQQSSTKDVSKEERIKQAKEAVQRSRERRALGENATASSQSSGKTENTSSLLPTHKAIHTKGLAASALTSTSFSPVTRNEHAIISEEDYMLVPKRIWHKGYARLVTNFGEINLELHTEYAPRAVYNFVELAKKGYYDGTKFHRNIPGFMIQGGDPTATGRGGQSIWGKPFRDEVTNPLTHDSRGVVSMANSGKNTNGSQFFICYDAAKHLDRKHAIFGRVVGGMSVLDALERVPTTETDRPKTTIQIENIVIYVDPFELWREEEQQKVKEKEKHESSLHDEENDRVTWTGKRLGITGESSSGSSSSVPVGKYIKAAEEKKPSFVEPSLPKKKKARTGFGNFDAW
The following text describes a protein:
Function:
Plays a role in the protection against host NK-cell cytotoxicity by up-regulating the cell surface expression of HLA-E independent of TAP (HLA-E has an inhibitory effect on the cytotoxic activity of the NK cell). Also promotes cell surface expression of UL18, another viral protein involved in NK-cell evasion.
Sequence:
MNKFSNTRIGFTCAVMAPRTLILTVGLLCMRIRSLLCSPAETTVTTAAVTSAHGPLCPLVFQGWAYAVYHQGDMALMTLDVYCCRQTSNNTVVAFSHHPADNTLLIEVGNNTRRHVDGISCQDHFRAQHQDCPAQTVHVRGVNESAFGLTHLQSCCLNEHSQLSERVAYHLKLRPATFGLETWAMYTVGILALGSFSSFYSQIARSLGVLPNDHHYALKKA
The following text describes a protein:
Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Sequence:
MASLAFFRKPSFHFISRATSSIISINNNASSFVSLQRSMATFTPTKPRTIGHVDHGKTTLTAATTKVLAAEGNAKAIAFDEIDKAPEEKERGITISRSHVELPIVSGSGLYALQGTNEELGEKAILKLMDADPVRQLYRPFVMPIEDIFYIQGRGTVATGHVEQGTIKVGEEVEILGLTQGEPLKTTVTGVEMFKKLVDRGEAGCKVGLLLPGLKHGDVQRGMVIAKHGTLKTYKKFEAQIVYVLSKFYLRTADITEKVQLPDDVKMVMPGDNVTATFELTLPYPLDHGQIFSLREGDRTVAAGVVSKVLS
The following text describes a protein:
Function:
Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.
Subcellular Localization:
Nucleus.
Sequence:
MGGGGGEGMEVEVPLSTGAFEAMWRDHGLRPVLQLADEPRMAAETGQYRVALSDGGERLQPGILAASLNHLVARGALRCGTVIRVLEYFAGFYHNQKVVIVIQLEILHAECTLIRNPTIFEANATQHIGVSCSGGLAIHEPCFMLCTQQVTSNPSCFPDKRVLDSSVTPKAEPTVINLPFSECVCSMPAQSTVDAKMQQLSLKDHQNQRVMMTATGLSGVMAVQLTPGAVMAISKHADGNGTLQPMLQVVDLQMVNNVKNPSAERFQMVLSDGVYTMQCMLTAAENTHVLDGSIQKGSIIHLQEFTCSTIQNRRIIIVFKLYVLQSECNIMGNPKPYEMRNQPNEQVTNFPANAAQANTGTYSSGPGMLGSSAAPRPVQDVNNVPYSGSYGGYQGMMGRPFGHAVESVPNVASGLSYGTTSAHNNTMNVGIVQSNLQQPSLNSHQNPRFVVPSMTGGSSFYQQSPPGHMKRTPVSKNDANHLVPVAQLNPYQTRWKIMARVTAKTDLRHYSNSRGPGKVFSFDLLDGQGGEIRATCFNVQADQFFDLIEVDKVYLISKGLLKPAMKKFNSLNHEYEVTLDHRTSIEVCVDDDSNIPRQQYNFRQISEIENIEAGAIVDLIGIVTSVGPSSIVMRKDGTQTQKRTLQLKDMSFRSLEIILWGKFCDAEGRQLQLLCDSGSNPILSLKGGRVCDFSGRSVVTISSTQLKVNPDFQVAERLKQWYIIEGKNTAFISLSWGISNMSRSHVLKTIAQIKDENLGRSDKPDFITVKGAISHLKTDNFCYPACTMEVNGRLCNKKVMNNGDGTWQCDKCNKSLPNFEYRYLLLCQIQDHTGVTYATAFQAAGEAIFGHTAQELFMIQNVEQDDMRFTEIMQAVLRREYLFKLKIYEETYNGEQRVICSIIGVEKLEETNNLLKDVSRPILKDHSSYIPSVGSANLEAKQSLLTSSNAYGCATVVGDTGFAQSDGIWSAGRGAQACFKCNQPGHWSKDCLV
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MPLNPKPFLNGLTGKXVMVRLKWGMEYKGYLVSVDGYMNVQLASTEEYIDGTFTGNLGEVLIRCNNVMYIRGVEEEEEDGEMRE
The following text describes a protein:
Function:
May be a cell surface adhesion protein.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MKIKQQSLFSASILLVIALITFFHTTSAQLTPIQAPVSSPPSPPQQQPQPPAFTPPSPPATAPAPGFNTVPLVPVTPSGAPTPTIPKAPSIDIVQILRKAKRFSVLIRLLKTTQLINQLNSQLLTSGSGGLTLFAPEDSAFSKLKAGFLNSLSDRQKVELLQFHTLSSFISISNFDTLTNPVQTQAGDDPKRLQLNVTTFGGSQVSMATGAVNASVTGTVYTDNKLAIYQVDKVLLPLDLVLPSEAPAPAPGKAKGASPKTDKTKSGAAGDDSDNGDNKDLPAEASSAGSSVSFKFGVVAFVLGVGLMGEAMV
The following text describes a protein:
Function:
Putative odorant or sperm cell receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRITLSAITSFFWDSSSQTSLIFFSFIVIIFIMTVTENAIMILLIHRESRLHTPMYFLLSHLSFMDILHISNIVPKMITDFLSGNRAISFAGCGFQIFLSLTLSGGECLLLAAMSYDRYVAICHPLRYPILMNDYVSILMAGGSWLIGTVNSIAHTAYTLHLPFCGSRAVDNFFCEFPAMLVLSCVDTTHYERGVYSFSTCFFHMIVVIMYYGPFIFTYVRPKKYHIPGQDKFLAIFYTILTPSFNPIIYSFRNKDVLEALKNMIKSNFLHKNNRKSA
The following text describes a protein:
Function:
Regulates body size morphogenesis, but does not affect male tail development.
Sequence:
MNYLLTALIALLAPISVAYNVPHGFLTGEAVTSHSGPNDLDGELPATDEVKREKRGYFFPSHFQSDSGLLSRSEHPNEYLKKWITHEHNRYRRMVPASDMNMLYWSDELAASAQRHADTCDFRHSRGRINVGENIWAAPYSNYSDAISIWFNEVHNPRCGCNHAYKHCCGHYVQVVWAKTNLVGCGFSRCRDVQGVWGRGHRNVFVCHYNPQGNTVFVTARGQLYAMPAFTWASGDNGKCSNCPANAPACYQGLCYMPKNYEAPTTTTESTTTSTTTEEPTTTCEPDEPEAEGADNNQEEEEENNDGFRMRV
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as a non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells; Glutamate-gated receptor that probably acts as non-selective cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVKNASCNPVFFNVGVVLDFDTGFGKKGLTCINMSLSDFYASHSYYNTRLVLHKRNSPSDVVVTASATNFVISLGDKAQVPIISYSATNPSLTSIRSPYFLRAAQNDSSQVKSLTAIIQAFGWREVVPIYVDNEFGEEIIPSLSDALQEATDDQIAAELYKLKGMQTQVFIVDMLPSLGSRLFDKANEIGMMEEGYAWIMTDGITNSFSYINSSVIENMQGVLGTKSYVPNTKVLESFRVRWKRKFQQDNPTVHGVKLDVFGFWAYDAAWSLAMAVEKVGAKNFSLQKMNRTSGNSSTTALEGFGISQNGPQLVQALLATSFKGLSGDFSLLNGQLQSSTFQIINVFGHGEKLVGYWTPQNGLERKLNSTKTGRYSTSDVSLGSIIWPGDTTSAPKGWQIPTSDTRLKILVPVQDGFSTFVTVTYDLGLIHLLSMLYPYAKLNGETAGSYNDLVNQVFLGNYDAAVGDITIRANRSLYVDFTLPYTESGVFMVVPIKDNKSKKAWVFLKSLTWELWVTSGCSFIFIGFVVWILENRINKDFRERVVSNLARFVVILWCFVVLILTQSYTASLTSLLTVQQLQPTVTDVNLLIKNRNNVAYQRSSFVYGILKQLGFQDENLKTFNSAEELNQLFHNGSRKYGISAAFDETPYMKLFLATYCSKYTMIPPTFKADGFGFVFPKGSPLARDVSRAILNVSEGEKMKDIERIWFEKEASCADPNSLVSSSSLSLDSFWGLFLIAGVASAFALLIFAAMFLHAERQEILQQLRRLVPGASLWTRICVVLRIYDQWDLRSYTFQNNGLEAPIEAPAAVPPGGPAADAPAAGAPVGAPLGQPAGDIELISDHDIIRLPEQESN
The following text describes a protein:
Function:
Plays an essential role in the initiation and regulation of chromosomal replication. ATP-DnaA binds to the origin of replication (oriC) to initiate formation of the DNA replication initiation complex once per cell cycle. Binds the DnaA box (a 9 base pair repeat at the origin) and separates the double-stranded (ds)DNA. Forms a right-handed helical filament on oriC DNA; dsDNA binds to the exterior of the filament while single-stranded (ss)DNA is stabiized in the filament's interior. The ATP-DnaA-oriC complex binds and stabilizes one strand of the AT-rich DNA unwinding element (DUE), permitting loading of DNA polymerase. After initiation quickly degrades to an ADP-DnaA complex that is not apt for DNA replication. Binds acidic phospholipids.
Sequence:
MERGDQIRPDARHRISSCLTASRVVQSCSTRSLPFAVVASPPNVNSFALERPSLRRRRRDSEVVRPIIPLFYCGDENRLAGYVCENPIETLLEISRPMLLVGQPGTGKTALALHLSKRMSISNVWEAMEMDKDTAQGGPSGVTSRVLSSRVLYQPAIDFAREFASSIDSKDMPRFREKLDTVPILVLDDLHLIADKGPAQEELAQRLEARDAEGRLTIVTCRRLPSEVRGLRPALVSRTLPGLTVTLHPPAGDTRRTILRELMLAHLPDVEPEALSLLDAGLPAESTVRAFESAIKQVALWCRMHEQPICADAVQSAIETAGGSQSISIKAITTAVARQLGVKSADMRSGSRRQNIVRARSLAMWLARRLTEDSLTQIGDAFGGRDHSTVLHAIRKIDGSLDDDVLLRRSADQIMEKLSN
The following text describes a protein:
Function:
Probable methyltransferase required to silence rDNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKPFEVPPWEEGADIIEFEPVNPSGNGVAAKKKPKKKKPKKKKAAVPNENLNVNKAAEKFTYRQGRGPLAPPQDSSDDDYEDVEDGIRAMHKVKSGRIEKQRPPTQATKGGKKELKLKPELAQAALEAMEATSSTTPAANSLASKLQSELLGGRFRYINEQLYSTTSRKAEALFRKDSSAFEAYHAGYRQQVEKWPINPLNRIIKTIKKIPKTAIIGDFGCGEGKLAQSVPNKVYSMDLVAARSDIIACNITDTPLQARTLDVAVYCLSLMGTDLNEFFLEANRVLKLHGTVYIAEIQSRFQDVREFVRCLNACGFDLNKKDVAVNYFYFFQFKKMRHVPKNTKMKAFSLKPCLYRKR
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.
Sequence:
MAAQISETDQINQFQEFLGIYNKLTETCFLDCVQDFPTREVKPKESTSLSAKAEVLGQPR
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MLFLPETAMAQKEQEMKNIQVRSLLQGGVTFEDVAVDFTQEEWQRLSPEQRDLYRDVTLENYRNLVSMGGEDSTKPEVILRLENGEEPWMVGTQELRSCSPAGKDWAIEEQSWRFQDIEQNLKTEAVSANQERLTEHKDPERDNPTEKLLPSTDSVPLRVRLLEGDSCGKHLKHSLDKKSYAKNNTYNIYKRRIGNDPSKLKENQFLWNAHQKSLSSKSYLQSPLRTQAIEESFGHNTHRQAFSKKSRTDEHQNTDTGEKSYECDECGKVYKQKPSLVQHQKTHIEEKPFECQTCGKGFSWKSSCINHKKIHNEERAYECDKCGKSFKQGSTLLQHKKIHTGQKPYSCNDCAKAFIYKSDLVKHQRTHTGEKPYKCKVCGKAFAQKSNAIDHEKIHSKERAYACELCGNTFIQQKNLIQHRKIHTGEKCYECDRCGKAFFQKSNLHSHQRIHSEEKTYQCQECGKFFSWKLGLRLHQKIHTG
The following text describes a protein:
Function:
Ligand for transmembrane receptor PlexB. Plays a role in growth cone guidance. Required for both proper adult behavior and survival. Can function as a selective target-derived signal that inhibits the formation of specific synaptic terminal arbors. Function in neurons is essential for adult survival, motor neuron survival, and is important for climbing behavior and activity. During embryogenesis, plays an important role in correct salivary gland positioning.
Subcellular Localization:
Secreted.
Sequence:
MSLLQLSPLLALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVIQSMDQGDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDIGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSISGEFPFYFNEIQSVYQLPSDKSRFFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGTCVNDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNGESLSKLLDIFEVAPNEAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRCVRDPYCGWDKEANTCRPYELDLLQDVANETSDICDSSVLKKKIVVTYGQSVHLGCFVKIPEVLKNEQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDCHLGGSLLCSYNITVDAHRCTPPNKSNDYQKIYSDWCHEFEKYKTAMKSWEKKQAQCSTRQNFSSNQHPNEIFRKPNV
The following text describes a protein:
Function:
Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MPRDLEDEIFGGESDLSDFDQDERPTEDVQENLAEEGRQHEEDDGGLSHDPAPREGSHTYPKFRKDTTQRSSEQSSAPKKKNQQRNKRPDSADNGVPPDDGEAEVVIDPEEQRRQELYQRIDEAAGKNKKGKRRRRKGGDEDLEMMADEEVSRLRTEMLSAADTDIQANEERRPATGKLMLLPKVKSTIQKSHLETAILDNGVLEAVKKWLEPLPDRSLPALNIQRELLELLSKMSIDTQSLKSSELGKIVLFYTKCPRVDPTIKRMADQLVTRWIKPILRRSARSREPIPMTAPRPVRPPTGGAPNSQRARIPETVHQVFHNPARSQLDSTTDGPGGSQNPAMRNSTQKATAKKTREWARKIQDARKIQRMG