lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDEFKQLDLKKREIENRLNELEGVLLKERVTMDTPLLTEDGFPRSDIDVPSIRTARHEIITLRNDHRELEDQIKKVLEKVFSGFSKESLAANDETKLAQEADPLNFNAANYNMNDIISRSKILGRVKPFCVVDSVAVESPAQEAGLCIGDELVHVQNVTSLSELPTFISNNVNKTLDVLLIRGYSADGSTNLVELKLTPHKWQGPGLLGCHLR
The following text describes a protein:
Function:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.
Subcellular Localization:
Nucleus.
Sequence:
MDNSHVALVSMLLKAEGFSPYRCDRNIALGINLVSLTKVLRAAQNEDILTLKADDSPDAVNLMFESAETDRISEYDIKLMDIDQEHLAIPETEYAATVEMPSAEFQRICRDLNALSESVVIEATKEGVKFSCQGDIGSGSVTIRQHTSVDKPEQNVSIALSEPVALTFSLKYLVNFCKATSLSSKVTLCLSQEVPLLVEYGLGSGHLRFYLAPKIGDEE
The following text describes a protein:
Function:
Part of the AP-3 complex, an adaptor-related complex which seems to be clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. It also function in maintaining the identity of lytic vacuoles and in regulating the transition between storage and lytic vacuoles.
Subcellular Localization:
Endomembrane system. Golgi apparatus.
Sequence:
MAGSSSSSIMDNLFQRTLDDLIKSMRLQLLTESSFISKSIEEIRREIKSTDPQTKSTALQKLTYLSSIHGIDMSWASFHVVEVMSSSLFLHKRIGYHAASVSFNDSTPVLLLITNQLRKDLSSTNHFHASLALHCLSTIATLDLARDLTPDIFNLLSSSRVFIRNKAIAVVLRVFDKYPDAVRVCFKRLVENLESSDPKVVIAVIGVFCELSSKDPRSYLPLAPEFYRILVDSKNNWVLIKVLKIFARLAPLEPRLGKRIVEPICEHIRRSGAKSLVFECVRTVITSLSDHESAVKLAVTKIRELLVDQDPNLRYLGLHALSVAAPKHLWAVLENKDAVIKSLDDEDSNIKIESLRLLMAMVSESNVVEISRVLLNYALKSDPEFCNEILGSILTTCGRNLYEIIVDFDWYVSLLGEMTMIPHCQKGEEIENQLIDIGMRVKDARLQLVRVARDLLIDPALLGNVYLHRILCAAAWVAGEYVQLASNPLELIDALVQPRTNLLPPSIRAVYINSVLKVVSFCLECYLDKDEGTSSSHDGELASGRSEMFVVKNDTEAPELVATCEGSTYEQDEGFNPRNSTAESCDEDLSVENDSDRVVTLSSKKNFTHESVVNLLNRIELIFGSLTANQDVEVLERARNIFAFVQLIKAEIIDNSGQNADTVDKKYSQISTVIKSIRDAFSMELGPVSISAQGRVTAPDGLALKENLDDLKAICGDIELPSSVSFYTGGPQFGTTSDASSSNLLKNDESGQSNESTSLLEHRKRHGLYYLASDKSEIVPNDYPPANDPKSNSNINDEADELTKLTEQSVLLKKRTNQMKPRPVVVRLDDGDVAPVPNKRPERRDNSLSGAIKDVLGSETNPSLSQSNPLDKSSTKQKGKKKLGTDLPSEMKENLGDAEKPDPEIPNSSSKNKERRRRGKEKIVEGEESDQKGKKKSSHRHGRRKTHQRANSPLNVVSQTPVIPDFLL
The following text describes a protein:
Function:
Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Prevacuolar compartment membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSNYAQYEYLDISVSDPQLRRDDKGEYTVYKVHFDTTFEEYKIKTKDVYRRYSQFVELKRQLEIRFEEKKDKMAKFGTIPPLPGDTIFSLFGRGRFDPAFVDDRCKKLDAWIKAICAHNMLRFEKVFISFLEQDNWEVTSW
The following text describes a protein:
Function:
Metalloprotease.
Subcellular Localization:
Secreted.
Sequence:
MFFPVVFFIPFVLGAPTQKALEKILVDNNPDSVTNREKIRGIIDKAFENRVPRVQGRQGVAPPVTFAALNYGPKNNQTKKFEELNQDINEYTFESDIMLNEKQAKHIATAIENGNYRSKRQAIVDTTNFWSVSVPIFYQFDTKLSATNIANVRKAIQFWNDNSCLSFKEDNNAKNRLFLSSAGGCWSYVGKQVDMPYQMVSVGPNCDTFGTATHELMHAIGFWHQQSRADRDNYVYVDFSNIIPSQAYNFQKMAVDQAQLLNLPYDYGSVMQYYPYAFAVDSSKYTILAKENGFQNSMGQREAPAFSDIIGVNKLYNCTSQCKIQMKCSNCGITDSRNCNQCKCPRYFTGASCDSLPSGTAPNCNGAVLQATSSWETFDAKAGDPSSFSSSTDNSTNCYWHIKAPEGQQIEFKMTKTPLAAICMQECPWQSIEVNLGKFDLFGMITCCDTILNQVFTSELNMIALRGIIRYNQLTFSIQYRAVPSSKPASTNACLNQ
The following text describes a protein:
Function:
This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity).
Sequence:
MGIVDEFQALKAETDADLLAMQVGDFYEFFAADARTVASVLDLQVSEKSNHGSSYPMAGVPVDDLTPYLAALVERGYRVAVAEQSETDAGDIEREIERVVTPGTLLASTDADPRYLAAVVREAGGDWGLAFVDVTTGQFRVTRGADRADAVTELYRFAPAEVLPGPALRGDDDFLGVLRERTDATLTLHDAGAFDAGRATHRVREQFGDGVIESLGVAADGPVVRAAGAAVGYIAAADEGVLASVSRIQPFGGGDHVELDATTQRNLELTETMTGGSDGSLLATIDHTASAAGGRRLAAWVTRPTRDRAELDRRQAAVGALADAALARDALGDVLGEIYDLERLASRAASGRADATDLLRVRDTLAALPDVADALTTTPELAESPARDVLARVDRAAAADVRAELADALADDPPKTLSEGGLLQAGYDEALDELLAAHDEHRAWLDGLADREKDRLGITHLQVDRNKTDGYYIQVGNSETDAVPDGEDGAYRRIKQLKNATRYTMAELDSHEREVLRIEAERAELERELFAALRERVGERAAVLQDVGRALAEVDALVSLAEHAAANQWVRPELVAGDGLDIDAGRHPVVEQTTSFVPNDARFDASRRFQVVTGPNMSGKSTYMRQVAVIVLLAQVGSFVPADAARIGLVDGIYTRVGALDELAGGRSTFMVEMEELSRILHAATSDSLVVLDEVGRGTATYDGISIAWAATEYLHNEVRATTLFATHYHELTALADHLDAVVNVHVAAEERDGAVTFLRTVRDGATDRSYGVHVAALAGVPEPVVDRARGVLDRLREENAVEAKGSAGESVQAVFDVDSGGFVDDAGDDGEADDPEAAAVLDELRTVELAETSPVELLGTVQAWQDRLED
The following text describes a protein:
Function:
Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting.
Subcellular Localization:
Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. Mitochondrion membrane; Single-pass type II membrane protein.
Sequence:
MPKKNKVKHVVLPRRYTFDIRRIQVRLGRYLNIAIYKPIKRRNSQTATNPADENHLNTIDDTSTSENADPPVVFFIHGVGGSHLVWQSQLEHFSSHGYIAIAPDLLGHGNSDTPRGKNKYTFEEMSKDVLSIFDRYCHRKNNFLVGHSYGSSFCALTARERQNRVLKIVLISCGLPSPLQPHPGCIFSSPMLLLKCVFPLVSKHFIRNAYAKHNTVKVKKRGFLVRPYALKHTMLGQIWEEGDESYYHELHLPVLIIHGEQDKLVDTEEDLKLQEVIYGSDIEIVEEAGHNVMMEFPTKIDRVIMGFLRRDFSHLFGADVWESMNRVQARSFRYGNVDAIKEED
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MGEMLVANMKDNLPLIIIRPIIVISTHSETFPGWIENTRDIDYVIDKYGKGLMRSFVGLPETVLDVIPADMVVNSMIIASVARSKNLCRSLIYHIGSSSRNPFKFSDLVDGMHCYFSKNPWINKNDTLVHVGKKLTLFSTTMDDFDKNKVFVCKRSELYRPYGLFEGIFDDQNVEKLRTVAKRVADKAFNLDPKNIDWKDYMMNVHFPGLVKHSMRSKM
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MATPTCKTMLLMAFVAAALIPASLAQSPLQNNFYGSSCPQAEVTVRNVTEGIIRNDPTMGAAFMRLFFHDCFVRGCDASILLDPTANNTQVEKKAIALRGYDAVNKIKAAVESVCPGVVSCADILAFAARDSAVVSGGFASFAMPSGRRDGTVSNFIEVLQNIPSPTFRLQELIKNFAAKGLSIDDLVTLSAAHSFGQAHCSFVNGRLYPTVDPTMNATYAGALKTVCPPPGSNGGDPVINNNRVTDPNVLSKQYYSNLVTGQVLFVSDQQLMNSSYTAAKVANNSADAATWMGQFAAALVKMGGIQVLTGTAGQVRKYCNVTNGY
The following text describes a protein:
Function:
DNA damage checkpoint protein required for chromosome break repair and for genomic stability during development.
Subcellular Localization:
Cytoplasm.
Domain:
The EEXXXDDL motif is required for the interaction with ATR/mei-41.
Sequence:
MAKRFSAMKDFARCKKPRLDVSVTRGSARPSPPRNNFDGILWDDDDDVILMATQLAEAEIEAEERKKKGGTEVDIGNSEVTFSEFAPTFQGSTSTQQMFPPPPPPQKKPTSLDMDAIFADDDDFDFLAVTLMDSEPQKMPEPKTSTSRITTSSISVQQKTTTTTTINATQSRQQEHQLKFLMDRIEALKRENAQLEKNLGDSKERNEIKSGEVSLLRDELKHLRQQLQASKMEKLALADETNRDCNKKVAEAAKQIAAKDIELKIKNAEFSKLKTQQKAHERSMNSSMSILQAAPDPLEKRLSLRLNRLNIHRSVPGLKTDNGSVFEYSENEDQTKKRRNHFELELKQLLLHYARLQAKPESVDNLLPRILSSVGKVFTEFASYAQSLDFPHNCMLYPYNPHNLEEEVHRISLTHQSCLYDNEKAVPLRRFIATLALICRREERISRGLTEWKENDLGLLDMAIEAITKLGFSYEVGQHFGLLEALTSLLNSLLQENALLQHNEELLFDLLKQLVFTRPSPWVFAELSSCFLSCLRHPQLMDKMCVNSPKDCFVSDRVRSVYRFGPDSCLLQVYAGLLELCFFSETPLRQDYFQLLLKIGGNHVRFAFECFKNPPDFILEMLPYFADDGDEDSSDGTLMKTGTSLSFNSTGAVQGSVSNGSTSASVSNPNQNSNSSTTQRGKGCECYVKLCLSAVTIVFQVMHQWMLHSRKAGTEEVGEISRIAVHLLSLVFHEYYLTCLFRDSEETTKHYLSLICNWWSEHANLLGFQSIHLRLLNQLVKAHFMLKPLHLEAKPNNPVNDLSEWKRIVKNADDQRAVKSAVTVDPSKLLNTDFFSALKREENTFE
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MGAIKEEGESVGWWDPESDYSSQEARQRQKTCQQSEDQSWPRSCHSICRICQEAFRTETELQIHELIHKKRRSFKCHFCHKAFSQKGDLTRHERVHTQEKPFKCDICQKAFAQKCFLSRHKRVHTGERPFVCQTCQKAFAHKADLIRHQRIHTEERPFKCSTCAREFGDAANWKRHERLHRGERPFKCDVCERGFSQRSVLNKHQKRCH
The following text describes a protein:
Function:
Probable polyketide synthase.
Sequence:
DNKSNKFLVAIVGIGFRLPGKSNNPVQLWNNLKNGFNAVVETTDRWSDNFYESGSHASNCAGLLEDSEWKQFDPSFFGITSENAKQMDPQHKLLLKLTAEACEDANISLFSIRGTETSVYIGQSSCDYTYASFKNDSDNINIFNKTQCSAANRISNTFDLRGTSLTIDTACSSSLNAVHLGYNSIKNGDEVSIVGGVNYILEPKITNYFTKLSMLSKTGSCKVFDKDADGYVRSEGGGVVILKKLDAAIRDNNKIYCVINGSGSNVDGMLNKLNYLAPSKLAQANNIKNAFKSSKNSLEINDLDFLECHGTGTPIGDPIETEAISIVLNELNRSKENPLLIGSIKSNIGHCEAFSGVASLIKCCLMFKNREFIHNINFNNPNPDIKFKEWNLKVLTQPTPFPNKNVLIGINCFGITGSNCCILLKEYNKNSNHNEKLVKEIDNCYYLIPFSSASKKSLENYQELILHNFSNIRKSIDFKSFVQYQINCKPTQFFQRSVAIASNFKEFKEVLSKKLNFISNNGERFINDSIVSTKSNSLSNVNTNFKNPPLVFVFVGQGPQFSKMQLNLYQNNVVFKQSVDKLDGILSKYYGYSIMEKLRSIKDDDLVSIGEPILAQPSLFIIQVSLYELYKHFGIIPSIIIGHSFGEVTGAYCSGMISLEDACKIVYYRSTLQNRLNGTGRLMVISLSEEQFKNQFSNKYPSIEIACYNSATTIVIVGNEDEIKEISKQLNEKQVFNFIMNTTSSFHSSKQKLIKSQILELLKDIKPKIPKITHFSTVTTNPFDEITLFTSEYLYRNLRKPVFFHQTIENIFKHIEDNNLGTAPIFLEITPHKTLTVFISDTIRQESNYFKKDSISILSPLNKKETNEMVKINKTISEIYCLGYNINFNSQFNISDLENISKVKSSFKVSDTLPRYQWDEEDHWVIDASFKDYLLNGPSINHFGIENDNLPFISRSTLINIDKKGFSYLSGHQVRNKIYVPGCLYIDILIGIFNDHDLTISYLEFKNPLILETGESKHLQTNLIKISRNEYKVTFHYKDNKANKWVLTSTGKVLLLPHGSTSNNKYNLQEFKDKCNISKLKKDELYSNIIHSSGLNYTGAFRRIVKAYYGNDCTFSKVELHQQEITNNNNKFFFDPSILDSCIQSFISFIQEKIQMVFQRVENFKVYSSNIPKNLNQNSYLYCYSEFKHTYGQFYHANLKVFLKDGTILLESPELVSMSLNEIIDPLKIEIDTDLYSKYSWQPINSPINNSKNSLPFVFLKGGFKIEENYQYKKKSSSIGISKLFFDNFNKRNPRITYNTIQEKSIDQLYNEFYKIKDTIVNKRKFYRVFEIIKENIQIIKEDNFINPLDDENNFGELKLLLQETSTFISKQLLPLESEVEEDEHINIQNGTVEKIYNIHYLKKLYGIISCVVKESIEPLINEPIHFRILEIGGGLGCLSNHVVEKINQLIDIYPNYQIDIEYTFTDISRGFIEISKSKLSIKENIITYKLLDINQTFESQGFRNSYFDFIISSNTLHVARDLRFTIKEIYKSLSPNGQLIFIEPVYKNPVNDCFVGYFEHWWSQADTDLRKDHCTLSNEQWNKLLYEAGFINYQSFDYDSNICFVNKAIKPTFHFNKNQKPIKEQEENIIIYGKSSTFKKLFNNDHQLFNKFHFIETFEEIELNQNLITNNTIIFFISSIETLELNQVKQISMEYINVNKILYLNSLSTKFIVLSLNSEKESYNYLVGSIHGAMKYYGDFSSLKLYSFDFDNESFNDNIIVSIINYIDSNSFYQRQVAVRKQNIFYERISPHRNLKLKYKSSSFENEITNYNAILDANLNYKLQSRVFNIKDDYIEVHVKSYGLNFKDNLVYRSLIPLELRSSKGNVNEPEFGIEYSGVISRVGRNVTKYSVGDCVIGLSNCSSSFFILSHQDLVLKKPENLTFTQAASIAAVFLTSYFSIFKVGNYKKEFNESILIHSASGGIGLSTLYLLKYFNIKAPIFVTVSSEEKKQFLLNHYGSIITAVYSSKDSDFVRNIKEFFIERGSNKTGVDIILNTLSNEFMDSNFNCLNQGGRFLDLSVTHLNPYEFTDFNKFKWYISYHSIELLYVPSERLKDSICELSPIFETMDFTHYPIIEYDTSKVKQAINSMSNRSHIGKIVVNVNENLISNIFNQNKKYYDMNFKILKSNYTIQNQALGKTILLTGQTGLILEILKWILKLSNEPKNIIVLSKSPIKWEMKVTIKKNLGKHSVFFESVDISNCKQLEDTIGNVMKINQIETINSIFHFAFNTCTSQPEEVSLNDLNITLDAKVFGAINLHNLSIKYKWNIINFIMASSMASALSSPLQCAYSCANNVINLFSNYRKSLGLPSTSLNLGKFDSKGYVSRNEKVNNLLDDFGLISVSLNSLLGILDLLIQNRNHEPNQILNRFGEKLFETLKSNSFSYKMDYIINIKSSFLSKKTNVLDGNESVYDIILTLIANKFGIEKSKIDTGNTLVEMSADSLILVQIKSWIDNDVKQNLFTIPQLQSLTLGTIIKIIIKEKPNLQLLKSKSKAIYNENNSSIEPNTQNENEPIQTINNSENRSIEFWLNESKLDESIQIPTNIIHQQVLSLENTDLVIFCTGATGFLGAYTLFNLLLKSKSKSIYCLVRNKKSTKECYDAVINNLKHYNLYNKIKEKSIDINRIKPIIGNLNQDKFGLTQIEYDNLSIEIDLIINIATNVNLIQDYEELKQSNINNIIKLSCHKKIKKLVHISSIAVFNNYNNINNNNINNNNNNNNNNNNNNNNNMISDETLPIINQDINFLNGYIQCKIIQDLLINQASNLSIPCLLIRLPFLSWDPENDICSKDGLDSLLINSIYSTKCYFETNSMSLFSPVTWAAINTVNLVFNKKSWENSINNK
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
Sequence:
MADRGVQSRGVKQLIDAETRAKELVKQARNEKILRMKQAKKEAVDEIERFRNQKQQEFDAEGVKNTGSSTQDSERIQADTTEKLKAMKTSVDANRSKVLEILMDSVCKVETRVHENYVKN
The following text describes a protein:
Function:
Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
Sequence:
MEEKNRVGKKEDRIMGINNGTGQQHPKIFLSGSIRGGRQLLEIYRLMYDSLEEAGADVLSWHVADPGLEENESKMTEQEIYARDIGLLTKSDALIAEVTVPSIGVGYEICRALVRKIPVLCLHRPEAAVSAMVLGNPDPSLEVRTYSDKVALKEIIVEFALAL
The following text describes a protein:
Function:
May function in an early step of clathrin-mediated endocytosis. May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors.
Subcellular Localization:
Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MIHFFHTLQGEKNAGFDVLYHNMKHGQIATKELAEFVRERAAIEETYSKSMSKLAKMASNGSPLGTFAPMWDVFRVSSDKLALCHLELMRKMNDLIRDINKYSDEQVKIHRKTKEEAIGTLESVQSLQVQNGHLQKTREGYHSKCVELERLRKEGVPQKELEKAELKCKKAAESFAGSIEKFNRAGGDFEQKMSESAQKFQDIEEAHLRQMKLLIKGYSHSIEDTHVQVGQVHEEFKQNVENIGIENLIQKFTEQKGTGKERPEGPVGFEEYLSSLASENSKKSRAKAFRIPGLGKRDKEPDSTVHVYFLQNNSPLEVDDEGFVIRADVKQNDIEKEGNFYSSDSDFDDEEPKKFHIQIRPVASSNRSNSAANEQELKATVGALTLPPNRVVSVKKQLSRRSEGEGESVPQRVIAKVEVCACRLSSTASGSDALFGPPLESAFKSHSFSGREQLQNAFAASEFFSKFYSSSLENVEDSGLDSPSHQPLGVSPDPTGWAAWPSSQSQSKDSINAASQSRGGSNRPTPSPNPAPSSQSNTEWMNDIIREGPYSQIMQDSSERLALAPPRSVRSKRSSVAITRKNSDFSRSLCSSPLPDPNASTCVLYSKMLNCAPAGLSRGPSPISLSAQESWPVAAAITEYINAYFRGGEHNRCLVKITGDLTMSFPAGITRIFTANPNAPVLSFRLVNISRVDHFLPNQKLLYSDPSQSDPDTKDFWFNMQALTLHLQREAELNPQASYYNVALLKYQASSQDPSRAPLLLSAECQRSGTVTRVSLDYHCCPATAPATQLTSVQVLLPLDHSATDLQCQPPAAWNAEERRLLWKLDDLSSVSGSGTLCASWQCLEVPRGPAPSLAVQFVGSGASLSGLDVELVGSRYRMSLVKKRFATGKYMAGCSL
The following text describes a protein:
Function:
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
Subcellular Localization:
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Sequence:
MTHHLAPLDSLPTSIYPPSAYPPPSFFESSSLIYPALLIPAKRTGEVQKTLKDVIFTEPKRKSVYPLEEGVDYSSIEVSAEGGYDPMKERKVVLIRLGDIAGKNEEEQITGIKEDPVFQDARVKSMLLSAKINIGAEPSTAPNAATNVEEVPSSFEIAGHVAHVNLRSESLPYKYLIGKAILDKNPKLRVVVNKIGNIENEFRTFPMEILAGEGLDLDLLKEHGCRFKLDFAKVYWNSRLQGEHARLVQYITKPKECIVADAMAGVGPFAVPLTSALAPHYYKTTVVCHANDLNPISYKYLQTNAQLNRCFADRLITYNLDGREFIHKMNYERIEADHFIMNLPQMAPEFLDAFRGWKFDDTTGHRPIIHVHCFDEKTRNEEETARMETHVLQRCEAALGSSGCLVDKRQENDVQIRVVRDVGPRKNMLCVSFRLPVEVAGVEKLLLTKNSDAEVNGKRKRENYDCVAEVSNVSKKERDS
The following text describes a protein:
Function:
Required for wild-type expression of ArfA and ammonia secretion, not however part of an ammonia transporter.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MDFVIQWSCYLLAFLGGSAVAWVVVTLSIKRASRDEGAAEAPSAAETGAQ
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSLNNGRIVCLLAPKREAKKWKNILEENKQFYKQIGIKNAKDRLSEDEVSVQGNFSDYILLPTLFHKIEDINISSLLKDDSVQWVTVSLNKVDFVHKQSLQDRVLQFVRSVLEKGEITASAYPIPSRFCVYGPMALLSSNSFSTKEWKQFFEEQKGKETLTNLYKILCEEWKTTHLAINDLIPTDDIMRRPCNLRPLFGNFGELVLKWPTQQDFDNAFWVHCRQNGIYQCWAPRYTMFSRGNIVEKARLLSQPCIQGEFIADLYVGIGYFAFSYIHAGAKTVFGWEINPWSVEGLRRAAIQNGWTVCIVQHDEEYIHSPGTHQLVVFLESNEFAESRLRKMNVNARHVNLGLLPTSKDSWKTAAHILSPTPKSTIHVHENVASNEIVELQNHLIETFSQFLELKHLSCSIHPVKQFSPHVEHVVFDVVIQQNN
The following text describes a protein:
Function:
Catalyzes the hydrolysis of glucose from the disaccharide unit linked to hydroxylysine residues of collagen and collagen-like proteins.
Subcellular Localization:
Secreted.
Sequence:
MIINSQEYLQPPQWWNERVEAGNLLSISNGEQEPTNYLMTNVGNGYVAFVIGGESIYVGGVYNGPAINLGDANNLPSHRAGIPNFQNIEISNAQFQYAGLDIENATYTRVYSIPSSPGTIVKQIFYAHQKIRNILVQEIEVDNSNIETDVTLQLSVVGINLTANVDFNILNLTNTQFTGNDYQLYNLTIKVPEVNFMTSVAVTTTTIPQSITIKSGEKKKHHYVTSFLTNIETNDYIEGSLDIYKTTFLLADQLIKSHLDEWNKIWISGIEVGGDSHLQQVVNSSLYYLFSSIRDDWSYGMSPGGLASDGYNGHSFWDTETWMLPPILLLNPKLVRDCLLQYRINNLPGAHEKALSYKSNNYTGFMFPWESAFTGIEVCPTFAPTGILEQHITADIALAIRQYYYLTGDLDWLIDFGYKALKGIAEFWASRVEYDQLNQQYSINTIIPPDEYAVGVNNSVYTNVAVKMTFEWVIEVATLINDTENIPFEHWSSIANGLVILFDEVNQWHPEYQGYNGETIKQADVVLLGFPLMYNMSKEARKNDLIYYEAVTTNSGPAMTYSMHTVAWLELESLENATKQWFRSYNNCNNSPFLVWTETPTGGAVNFATGMGGFLQGLMFGYGGVRIHQGNLDFYPQLPEGTTSLKIRSMNYIGSTFNVGWNQTTITFEMLTFNPSVYLTLLSTEYDNIILNTLDPIYLTFGSKFQIYFNNNN
The following text describes a protein:
Function:
Involved in the binding of tRNA to the ribosomes.
Sequence:
MNSAVKYPELKIKLESYDSTLLDLTIKKIVEVVKGVNIKIKGPLPLPTKKEVITIIRSPHVDKASREQFEKNTHKRLMILVDVNQGGIDSLKKIKIPVGVTLRFSK
The following text describes a protein:
Function:
Probable serine/threonine protein kinase which may function redundantly with MPK1-independent branch of the PCK1 pathway.
Sequence:
MSAWASQEAAKEEEAVGDFARMLERRDAGLLARVLSRAQTGPEAYVRGLWRAEVGLERWRLTRVLGCGSVACVFELGDGALALKVPTSRRKAPVLLHEVLIYSHLAQQAGGRLAERHVVPFHGVAAVTRREYRRLRGGEVVPALVLERMDTTLEAVHRRAAVSKGQWWRYARDLVAALQFLRESCVVHGDIKTANVLVRGQDAFLADFTSAAVCDAAPEPLTTTLEYCAPGLIGGGQPTHSTDVYAAGLCLLALITRFEPFRELSMMKSHSSAPTHSLHETQWLMNAISKGDPIKYNVLSQDLYDRWAEELHFLRRFFVPAAQDALSRWLAESNARVAEHAF
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MADEVSAYAAYGKTLPKKQAPKRRQAKRWPKKTTKQTPKTLAKRTAKRASGDKANGQNNGAAAKRQNGVQTKPKAQKLGTHDNASADARRIDSISGSIHCNGVNSNNNNNNSSSSSMPSKKNKGRRSDVSDTEQSESLDDTVNLARKMADYLSECGEQNCGSDADSSGSSYGEYDSSDNDDNMSGESGSASESESCSEDYDKSSGSDSDNECGDGDSDVDCDSDVDCDSDSEGGSAWGSESDDQFSEEYTLNSHANSSSNNNSSNNNSSSNNSNSSASSPEASVMPAAGRRKATKRSEHLASNSDGSDFIDSNNNNKNKNTPPAAKQQKLQVQQRLKQKQLEKQEKRANAAVQRENAAPFCPLQRTATTAAKSCPLPSKEAAGAKPGRKSCPLPSKSAPAANKMAPNKMAAKMCALPPKNERAAQQQRKRAERDEQRQEAKGRRSENELLPEGKQRQQVHLQDSIEEGKRMLHWLINPMTSDDFFSQYWERNACQVKRKQPNYFSQLISFKLIDEMLIRNHLEFTTNIDVTTYKNGMRETHNPDGRAMPPTVWGFYSDGCSIRILNPSTYLIKVRQLCAMMQEFFHCLVGANVYLTPPNSQGFAPHYDDIEAFVLQVEGRKRWRLYSPLHPSDVLARNSSGNYSQAELGEPLFDAVLEPGDILYFPRGTVHQAVCDQQQHSLHITLSVYQQQAYANLLEELMPAVLQRAIKHHLSLRRGLPLHIWQHLGLAKGDQKSELRDELLGNTKRLVQQYLMPSDAQIDAAVDQLAKRFQHEALPPVVLPEEHERTVFGSRSQANSHGQCLCDYELTERTSVRLLRANILRLVAEGSSLRVYYYVDNALEFCKYEANFMEIQPTEAAAVEALMSAYPKYLKVAKLPLRSAERRIEVATALWERGLLMTEQPFK
The following text describes a protein:
Function:
Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDVNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETSVSKKSNSSTFVLSRRSSSQRSCSQPSSA
The following text describes a protein:
Function:
Structure-specific DNA endonuclease that specifically cleaves single-stranded DNA and 3' overhang DNA.
Sequence:
MGVQGLKTYIESSSRNDLKTWAFRDKQLIIDGCNLFYSLCFDSNLDQIHGGDYDTFEKVVRQFFENLSACDVHPYVVIDGGDDHTDKKWDTLLTRKQKKIKDAYDLSVGKRRQVLPLLTEKVFKQVLKKLKVPVVQTLEEADWEIAALAEEWNCPVLSNDSDFYIFNLRAGLLPITHFHWRKVRVNRKTNQKFILSKHFIARKFCKSFKMNVSLLPVFASILGNDYVKLPNIKNRHWERYSNPGSENPQIEGLLNWLSQFSGPDEAISALLRPTSNKTKAQEELSHGIQDYKLVPGSLAQIFRSTKVPQKISKGPLHVLPRWTLRPILDGKMSSYIINVLLHNRASLNAQVEDFQLPSANETSLHIRQVFYGLLLLGEQQTAGKRESVKGTTKRYVVEYSRQQIKRSSENVEAIQTKAMEGLRLETLYQEPHAVRLQVILDTLGVSCEMLKGTPDALQLQMFVTRYWLVNAEPQPCRVHLWGLLLGMVYGKLSSSPNAQKDMLSRLRVKASRKGGSVDIDVAHAYSQWQSCLKYSLNLNYLLSFPLTEPDCASLYRGSLVHQAVGELRRGISLEALLVKGSSAERIFKQLKDIIVSLMGDDFIKKMKSGLEHRDAGKTQRASKGQKDELDIYFEQMMIESIDSEDEELLDVRKSKAKNHLMELPVCPIRARHKAKARNARHPCKKYERRCFE
The following text describes a protein:
Function:
Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MDRTHNTTSHGPDSSETPLKPTASATNLGLEEEKTSARFSCRSSASSSSKGYPHTVQVSQSKASQSDNVTDVPQPGRGARSSTRSSSRAPRRLSGSTAASSMSEVEPPPAFLGKIGVCALDVKARSKPSQNILTRLQSKGDFEVIVFGDKVILDEAVENWPVCDFLIAFFSDGFPLDKAIAYARLRRPFCVNDLPMQKILWDRRLCLRILDHMSVPTPKRIEVNRDGGPTLESPELAQHVYKLTGVKLDGPTDGTGGGTPKTKNVTLSDDGDSLIVDGKHFRKPFVEKPVSGEDHNIHIYFPKDQQYGGGGRRLFRKVGNKSSEYDPDLRTPRSILEDGSSYIYEQFLRVDNAEDVKAYTVGPDFCHAETRKSPVVDGLVRRNTHGKELRYITKLSKEEAILRDIFINERRRREGVAEAPEASFSDQSHYQWRHSVSHRHALKTLLKSPGSSKSNGNPQHQRDSDVGSLESSHPSLTAPSHDGMDFNNGRAGVIPKEQSASPGICTPQGANQPSPTMHSLEANPPPPASKHSWKLKGMVAVIRHADRTPKQKFKFTFHSQPFIDLLKGHQEEVVIKGESALRSVSEAVNLAMEQGLEDADKLKLLRTSLEKKGGWPGTKVQIKPMFRRRDLEGGNVKTSALSDTVEKEPNSLPIDAPQEGENIGRSQTRSDSISGATFSRFSAVENDLILDKLQLVIKWGGEPTHAARYQSQDLGLNMRDDLKLMNKEALNNVRVFTSSERRKEIPEGFIQVRKDLLDDSNAAKDLMDKVKKKLKLLLREGSAPSQFTWPKENIPEPSVVLATVVELMKFHRDIMRHNYEKLDRSYTLAPDAAEKSDELTSSRAADTSNENPAFSAIQGRWCTGEDPMLFKERWEKLFAEFCDTEKVDPSKLSELYDSMKFDALHNRQFLEWVFTPPDAEDSDEETADMYRRGSSRNHASAAESRGNGFDGSGHQRVDEQYSESQTLAHRLGLKRRMHAFETSIPHLRALDDSYDHYFKLYPSSNPSKTKLDSRLSKLRELYKLAKVLFDYVTPQEYGITDTEKLEIGLLTSLPLLQEIVRDLEEVQASSDAKSVFYFTKESHIYTLLNCILEGGVQTKIARSAIPELDYLSQICFELYEARDSESSTSSYSIRISISPGCHAFDPLDVHLDSRHAIGCAPRRSLTAHQDWKEVIETLKAKFNTVKLPKSFTAVNLSDKLVSRPQ
The following text describes a protein:
Function:
Modulates cytoplasmic Ca(2+) concentration and is crucial for proper stomatal regulation in response to elevated levels of external Ca(2+). May function by regulating concentrations of inositol 1,4,5-trisphosphate (IP3), which in turn triggers release of Ca(2+) from internal stores. May play a role in de-etiolation.
Miscellaneous:
MISCELLANEOUS: Plants silencing CAS show reduced chlorophyll content and early bolting.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein; Stromal side.
Sequence:
MAMAEMATKSSLSAKLTLPSSSTKKTLSLRQVSVSLPTSTSISLLSLFASPPHEAKAAVSIPKDQIVSSLTEVEKTINQVQETGSSVFDATQRVFQVVGDALKPALDTALPIAKQAGEEAMKLASPAFSEASKKAQEAMQSSGFDSEPVFNAAKTVTDVAQQTSKAIEDAKPIASSTMDTISSADPSVIVVAAGAAFLAYLLLPPVFSAISFNFRGYKGDLTPAQTLDLLCTKNYLMVDIRSEKDKEKAGIPRLPSNAKNRVISIPLEELPNKVKGIVRNSKRVEAEIAALKISYLKKINKGSNIIILDSYTDSAKIVAKTLKVLGYKNCYIVTDGFSGGRGWLQSRLGTDSYNFSFAQVLSPSRIIPAASRSFGTRSGTKFLPSSD