lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Sequence:
MGESNEDIDQMFSTLLGEMDLLTQSLGVDTLPPAEPKPPREEFNFSVGFKDLNESLNALEDQDLDALMADLVADISEAEQRTIQAQKESSQNQGHSALLEASDGQGTAPRGYGANAAAFDVSDYEEALPPPPADPMLDLLPPPPPPPPKPLSKEEEEALAKADKIKLALEKLKEAKVKKLVVKVHMGDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERIFEDHENVVEVLSDWTRDTENRVLFLEKEEKYAVFKNPQNFYLDNKGKKEKESNEKMNAKNKEYLLEESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNIYYGIQCKMKYKAPTDHCFVLKHPQIQKESQYIKYLCCDDARTLSQWVMGIRIAKYGKTLYDNYQRAVARAGLASRWTNLGTATTPAQPAAGLKTGTSQPNGPMPQAAPSPGPPLRETLTQTETTKDEKQGLANHSPGASRENHRPKSSLLPPPPPVRRSSDTCGSPALPPKAKGPGSCTFTAQPENFLPPPPPPPPQEDDNSMLLPPPPPLAYLDEPPDFVPPPPPPATVEDSALPPPPPPPPCLSQEMTKSSPLPAKKLPVPPKRQENQGLPGAPRNTEQDFMSDLMKALQKKRGNVP
The following text describes a protein:
Function:
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
Subcellular Localization:
Cytoplasm.
Sequence:
MEVLIKGEKRIININNILSGKETDIKEQLICKICQSIMMNPVQFCESGHVFCKECLTKWLQKNVNLNSNSSMCCPTCRQVYYYKPLFIEQNNFTMNQKYLLSSNNEIKRKINKIKVHCPYYFKNDELKEIEENNDNGCREIIRFGDVANHIETCEYRFITCSSQNNGCKDLRYKDKDNHYESCPYITLQCSLCNSDHLRKDEEEHLAICPNVKVPCKFCSSNIERNHLIVHYTECPDYLIECEFKDYGCNDTFKRCDKEVHLSQYRYHYDFNLKKINALSTELEKFKIYYSKKIIVFEKVNISEGKKSNIVSISKSLFGQHCMLYVSKKEKYSHFDVFIKSNNKTIFEGNYL
The following text describes a protein:
Function:
Tube-forming lipid transport protein which binds to phosphatidylinositols and affects phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) distribution.
Miscellaneous:
MISCELLANEOUS: Present with 1360 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane. Endoplasmic reticulum membrane. Mitochondrion membrane. Note=Localizes to endoplasmic reticulum-cell membrane and some endoplasmic reticulum-mitochondria contact sites.
Sequence:
MMFPINVLLYKWLIFAVTFLWSCKILLRKLLGINITWINLFKLEICGLSLEDGTVRLKSVRFAVFERKLFIKGLRIDSKKSSTNDLHKELPREEERTFIETPEDNGGGFISKILSLSQYWLNGVTIILEDTQLVNNDITIEKFGFFLSIDNSKHIKSLRFDSFLRKLLWNGQTIIADAIFIVNTNLLIGEIMNPLKDGLQVGLDLKLGDLNIPMNLLNLFINKENVDLMSNEKLLQRLADTTKANEELKDEDIAKMKDDLVYAMEKFVDRIKPLKEMNVTVDKLQIKDFPLTNHPELLGMNKYISYNVLVSNINFNTNRFRNEMPGYTLIFEERDSPFKFSIIMARFNIYLNLNRKHQSHAKQLKIIEIPNVSIFGETNLFSQKFRLSNNLHAKELENAIFNIKGNISSLTIDMDPVNISFIKCFLSNIKVFTSSCPKNKILKENSHVKFLTRRRVLFDYFKCFLPLINMKFTLDDPKFVINDKDDLIIGKFSVFMISHHSKRYTLGNNLMEEKEETQHIFYESHWNVELLDMKLQHIIKHQKYEHTILRVDSIAIEEKVQLLPDILCSANADIDTLMLDLSELPTMVMLSELVHNLDSQLANVEENYFKEFYEKFASNLQNMKAECSNMAKCLRQKEILPSDFMFQQLPDFFDYIKINIRDISSTLGARSVFMPRDVFSSVDSQSSKDLIDGKLRKYCNTVEKLQIALFGDKTQWHNKIGSNHATMVRSGQLTNFSKDNKQNPNHKSSIADLDDISTSDATEVNHLWNINLLVNDITTSIIGETPEVSEELSTKTVSKVSNLSIKLFPDTESFSSNESDSKIILQINHSRGTSVVSLMSIFLAVSGIHTLNQIFGHCIHQKMRQSKTKQYFLALSESKKKSCIKSIKWGQLKELLEINFSSEYISQIIALPNGLRTKFEPTSTFITVKNCNTISVSGQYFRMMVESPTQPNFWERMICINGFKVMIHIDLLKQQMKKLNSLQNWEKLPSAITLENDSWHFSIPHHFEMFKIIDSIPTIFKSIKQMLYSLKTSKDDLIIFPHKIETPLSLPKIKLKSKRWLFSISDDPLEAELNTIFQIGLQEQRERLAKLQEFNKRISEDLIKSQKNAKEMKDDFEAIDNAILKHRTGLWAKDGKKRLRKSATDSEIPLTPAALNINGKRDDRPDRTQFISPEIENAYNTLLANFSDSWIKRVKEYKVKERREFDKNFSFLWGFIDYTKLPKDINKKVLPFSTNPFLMNLIIENIDIDIIRPSCGIENIPNFIHDVGKGVPKNTEYSIMIPMHLDAKFSEVRWHLRDYPLPFVSIPPLSSTQSKETIPMRIYGDFMITEDMLQSDRELRTLFVPLIPSVTVENTDRYYSLFVPRTMTSAKIFTDLNFEINSNHTTRVTWGGSYQPAIQQTMQCLDNFSKPPLDPSVKLGFWDKTRYLFHGKINIVWKKRGKFEISLKGAKSPYMLGGESAGFIVGFDGNVNLKCNEDNDPKKFLSCSADKVHFSIPNYFAKPLLVWSRPSTNTMFIPNQDDTNMQRYASFYYLLNTTSSKNEKADKEIMGKSFIEKTGIKLSGGMTLDMGILFERLGPSLNERTFESKKHYLTRLCNPIYVQDLSKHDSYAGFRSDFIHMSFGLSSNSNSAYNAMQLSPNGFKAFFVWWKSFSGNFPVRRGPLFGLQSISPKFGEHLYTISYHADVSPLFINYMYHNADADQILRKNYLEVAEFAGLKAKSSHFIMDLHQRKEVLTEYQAGLNVRRRVMKLKFLAGDVVCQDVDIRTVSGEFSKLNYIEEKEDAEYDIFDNDMSWLDITDFQDAFFINPDNYLPKIKIMPFAFSPQFAYQKRASYGDKYQVDPKTCKPITPFDNRVSHGCTLGHNVSLRTDLVEKRVTVLKKFREKLQEGIRKNKSAGVSEENLNDLLSKANSSVENAELLLKDFQKIFKQHEAGQTEQPFHFDSLNLLKNTKKTLKQFEHRFFIFNVLLKWNEDARSAIFKFFYYANLSNEFASLASGKGLREFEDVIKQREMTDDTTSMEAIPEGTDKANTTKQCHSCDDTEFTTENLLNIFEKNITQLSCDIKNKIHHKFFVQFITPQIQLTSLENPEACVLVSSPFFMLKTLEFDANTTSNTYMQDIFLKRHGILFGNANAFLFNKKDYQEFFELYFGSSSYGQDKKEQWPPWLGLELGFEPSALKKKAVVRNISALLHHQKLAPFSAKYDSLKDKIEDNICGYVPQVNVQVNSDEYLMLTKMALKLFLYVEPEDEELKKYIEKLIIGYDIYDTAQTRKFVNDLHDSEQILAVVEKELLFKRSLLDDIGKLDLSNIHNERMHQLLRLYILRKVFTSNGNNYINRTLVWNIKVNETILHLLDKIDKPFLDIAVAKLNFQRIQHTMGLRKNTVTVKMMQIFDLGENVNYHCILGPLITSSGNDTVGLASDVPLVQITWDVDKPVGGIKVVKNVETTLSSLTIKLEEDRLNKLFEWLSLKELIYDGNGDDDDGASSIFDMVSSESEEGKIEFSEDISSDFNEMLKRSSDYMIVEDLKLNSFKLCISYKGKGKMRLANVTNFVFNFPTLRLSNQTLRVTDLLLALKKVLIKVLIKHTGRFIGNKLKRNSKENKIADDTSPLKQLTTYNSYTEPEELR
The following text describes a protein:
Function:
Has antibacterial activity.
Subcellular Localization:
Secreted.
Sequence:
MRLLFLLFLLLVCLAQKTSGRKRNTKFRQCEKMGGICKYQKTHGCSILPAECKSRYKHCCRL
The following text describes a protein:
Function:
Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MARAAVLPPSRLSPTLPLLPLLLLLLQETGAQDVRVRVLPEVRGRLGGTVELPCHLLPPTTERVSQVTWQRLDGTVVAAFHPSFGVDFPNSQFSKDRLSFVRARPETNADLRDATLAFRGLRVEDEGNYTCEFATFPNGTRRGVTWLRVIAQPENHAEAQEVTIGPQSVAVARCVSTGGRPPARITWISSLGGEAKDTQEPGIQAGTVTIISRYSLVPVGRADGVKVTCRVEHESFEEPILLPVTLSVRYPPEVSISGYDDNWYLGRSEAILTCDVRSNPEPTDYDWSTTSGVFPASAVAQGSQLLVHSVDRMVNTTFICTATNAVGTGRAEQVILVRESPSTAGAGATGGIIGGIIAAIIATAVAGTGILICRQQRKEQRLQAADEEEELEGPPSYKPPTPKAKLEEPEMPSQLFTLGASEHSPVKTPYFDAGVSCADQEMPRYHELPTLEERSGPLLLGATGLGPSLLVPPGPNVVEGVSLSLEDEEEDDEEEDFLDKINPIYDALSYPSPSDSYQSKDFFVSRAMYV
The following text describes a protein:
Function:
Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Miscellaneous:
MISCELLANEOUS: Present with 704 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MARPVNTNAETESRGRPTQGGGYASNNNGSCNNNNGSNNNNNNNNNNNNNSNNSNNNNGPTSSGRTNGKQRLTAAQQQYIKNLIETHITDNHPDLRPKSHPMDFEEYTDAFLRRYKDHFQLDVPDNLTLQGYLLGSKLGAKTYSYKRNTQGQHDKRIHKRDLANVVRRHFDEHSIKETDCIPQFIYKVKNQKKKFKMEFRG
The following text describes a protein:
Function:
Probable transcription factor that functions as a regulator of metal transporter genes responsible for essential metals delivery to shoots and normal plant growth. Required for the maintenance of metal transporter gene expression, such as IRT1, IRT2, ZIP1, ZIP9, NRAMP1 and NRAMP5.
Subcellular Localization:
Nucleus.
Sequence:
MFGDSDGSKDANPGAPPSTTDPPFPNRELTLSSYLCEKPTLASAAAGGGGGAGPSSPPNPAAAAAGDDGKHCVERDFLHLSAPKRGDPPGDDSSVVGGKKPRLDSLQLSLSLNSDGPAAPPSSQPPLASLLQPVPATDGDLRGAAAAAAVPAAPARRTYSATTARTRSINSDDMSYSYSIFSHNPSCSLTHNSTDIYAAGEGTNGSVHSRFNFRPMGDGSVAFATPPLKEGTSSFFPTELPARMAAAAAAAAASAGGSFDGGRGGLHASRPDKILRDIVSDSVTAMAQVLQDFPSERLELLREAVRGMIDSHEKRDELASLQRKLERRSDLTTETLGRANRTQLEILVAIKTGIATFVTGKGRVPSSELVEMFLMTRCRNLNCKSTLPVDDCDCKICSTKKGFCSACTCSVCHKFDCAANTCTWVGCDVCGHWCHVACALERNLIRPGPTLKGPIGTTEMQFQCLACNHSSEMFGFVKEVFNCCAENWNAETLMKELDFVRKIFAGCEDFEGKGLHAKAEEVLSLLGKKIISPLDATNSILQFFKYGVTDYSVTGSTSKGILAAQASQSTDMRSLQTPTITPPKSSFNFKTTTSILDTDALKPSPKPLSIEPHFSTASKEDDSSLETIVKCKEAEAKLFQKLADDARKEVDSYRQIVRSRTQKLEEEYAAKLAKVCFQETEEKRRKKLEELKMLENSHYDYLKMKMRMQTDIQGLLERMEATKKMWV
The following text describes a protein:
Function:
Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
Subcellular Localization:
Cytoplasm.
Sequence:
MDLITTTADLAAACSRLAKHPVITVDTEFLRETTYYPLLCVVQMASPEEAIVIDTLAVGIDLKPFFELMGNEAVLKVFHAARQDIEIIWHQANIIPHPVFDTQVAAMVLGYGDSIAYDQLVEKVTGHRPDKTHRFTDWSRRPLTKEQMHYAVSDVTHLRDVFAALDADLKKRRRSEWVSIEMEVLTSPRTYDFHPERAWERLKTRVRKPKDLAVLMEVAAWREQEAQSRDVPRGRVLRDEAVSDIATHAPNTLEKLAHLRSVPKGFEKSKWGADIVAAVERGLARDFSTLPKLEKPRNNSNGAAIVELLKVLLRMTAERHAVASKVIATVDDLEEIAASDEADVPALRGWRRELFGDAALKLKRGELALAIEKGRVIGVERA
The following text describes a protein:
Function:
Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Nucleus. Chromosome. Note=Nuclear at interphase, associated with chromosomes during mitosis.
Domain:
The N-terminal region seems to be responsible for association with chromosomes, thus excluding any involvement of the Zn finger in this process.
Sequence:
MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST
The following text describes a protein:
Function:
Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, involved in ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting together with mab-20 and allows the formation of distinct sensory rays. Probably acts as a ligand for lad-2 to regulate axon guidance of several neurons including SDQL, SDQR, SMD and PLN neurons during neurogenesis.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MEPRPMYVLLGVLAFTFPAYCRDYHDVIWNSRFFPQHLKHSPMNVRLGDQLTIICPKSFHRGMHYEYAKLYWVGKQDFDQCTHNTYYTKLMGVCANETETTAIKMIFQKYNPIPNGIDFQIGEIYYIVSTSSGHLEDISQPTGGLCWQENMKLAIRIVGEELPRMKYEVHDYQSLVSSSTSSPLSSTMNSLVILFIASKF
The following text describes a protein:
Function:
S-crystallins are structural components of squids and octopi eye lens. Contains relatively little if any GST activity.
Sequence:
MGDEVDPSKPILTYFNGRGRAEIIRLIFNVANVPYEDKRISKEEWQSLKPSTPFGQLPLLTMDNVVLCQSNTIARFLAKKYGLAGANEMENALCDMVVDCVEDALKPVLQIFFEKDDTKKLLMFAKFEREQLPVYMAALEKLLVSNRGEDGYFVGDNLTWADITVMNFREYLTMINVELSFGKYPIIATYIDRIAAVPKIAEWIDIRPKTDL
The following text describes a protein:
Function:
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDSSYWENLLLTINRFLGVYPSGRVGVLRWLHTLWSLFLLMYIWTGSIVKCLEFTVEIPTIEKLLYLMEFPGNMATIAILVYYAVLNRPLAHGAELQIERIITGLKGKAKRLVYKRHGQRTLHLMATTLVFHGLCVLVDVVNYDFEFWTTWSSNSVYNLPGLMMSLGVLQYAQPVHFLWLVMDQMRMCLKELKLLQRPPQGSTKLDACYESAFAVLVDAGGGSALMIEEMRYTCNLIEQVHSQFLLRFGLYLVLNLLNSLVSICVELYLIFNFFETPLWEESVLLVYRLLWLAMHGGRIWFILSVNEQILEQKCNLCQLLNELEVCSSRLQRTINRFLLQLQRSIDQPLEACGIVTLDTRSLGGFIGVLMAIVIFLIQIGLGNKSLMGVALNRSNWVYV
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC) and the spindle pole body (SPB), probably by playing a key role in de novo assembly and insertion of both structures in the nuclear envelope. In SPB duplication NDC1 is required for the insertion of the cytoplasmic side of the SPB in the nuclear envelope, thus allowing for the assembly of the nucleoplasmic SPB side. NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.
Miscellaneous:
MISCELLANEOUS: Present with 3030 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Central core structure of the nuclear pore complex. Spindle pole body, central plaque.
Sequence:
MIQTPRELLNPRYTYHTIFSDVCKTRFNHLVTRLFFICSIIQTVVISLLALPHSPLWELALAFIPNILALNLVSLLIIVTRKNYMHVKNFGFANSLTFILGQLLSVKFLVYQGVYSMGSILLSFVLGVVFGRGGSGWKPYYKLFIWLVVPTIYNLQHHVTDADKLSFNCENFFQAPQDYVLERVKRIMEKSVILSVISMFVLPIFTTVFFSRQKSGLFDSFTNGVLAVTNLLIISCIIFITFEFINIAFDAHMSIGCLHKGKLISNLSSTPMETLLSGLSADKPFTRLTAYQELAYRATSLDPSLRAPIYHSKFRSSSGNTWSLILNECLKTIQINNEKVVQYLRSVQDLGGSATARHKKKVENLDYMYENGKLTSANERLFGNRPSMMAPLRDNGLLDESPNRLRVRTDDSVLLNRGNKKRHRSSYYDNDLDETTQTFNGSIFTHETTFMTAMRLMLKKLKNSIMSFIFPSYAERQSSDESDNYRLLPNGSNKAQISIIDIWSISKKRQAEKLVPLPICHANSVVALTGLLIRSKTEDPKGGIIASVGDILKTLERSICALGEFADWDPESMAYTAFQTQRTAQDRVQQDSEDEDSMKDTTDMISVLYQLSTSAFMEIVLEYNVALNDVYLDADVAKLANWFLEVYASGNPNAT
The following text describes a protein:
Function:
Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
Subcellular Localization:
Vacuole membrane; Single-pass type II membrane protein.
Sequence:
MAAEEGRRLQMKNGEGVGRSGRPRWALWIAALMAGALWWTVHSDAVALMSKACGKDAATTPRAARALRGRFLHITDIHPDPLYVEGSSIAGACHGDPARDASDRAGRFGDAMGGCDAPMDLMNYTLAWVATHLRDEIDFVVWTGDNARHDNDRRQPRTAEQILHMNAQVADQFYELFQQQRDGDTMQGVPVVPSLGNNDVFPHNMFSLGPTLMTRQLQRIWAKFIPEEQRQAFEHDTSFFVEVIPDRLAVISFNTLYFFKSNPLVDNCNDKAQPGHALLLWLGSVLEEMRARNMKVWLSGHVPPIPKNFEGSCYNKLAWWTYEYRDVIIGGLYGHMNVDHFYPADGKAAKKSIKRRGKARTKERNTQEQPLDILDDSVDNLFSGRGAMPLRKEKYMRRLFKDVYCPIAKRLEDKGKQEQSYERYSMVHVAASVIPTFNPGFRVWEYNLTGIDNAVAPAPWTRLVRRAQQILSPLRKKKHGPDRTLPPKKPKHLAAGPGHIPQALTPIRFTQYYADLAEINKDYARELEAGRSHDEAAAAAFRYKIEYTSEDEPYPMESLLVRDYVKLASKLTEDRTAWKTYVRRAFVSSGYRDN
The following text describes a protein:
Function:
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
Sequence:
MKNRTFSMFYQEYEQLLEKEILSSEIPDHIAVIMDGNRRYAGQRGRTRSFGHAMGAEVTEQVIEWCYEIGVKELTLYAFSTENFQRSEEEVDGLFNLINEKFLKLYNDKRTYEKETQIRVIGDRTKLPAFLNKSIEKIEKATETHRKFNLNVAIAYGGRQDIMQAVRDIAACVSSGKLSLEDVDENLISKHLYPAPGVSVPNVDLIVRTGGDERVSNFLPWQANGSECATYFCAPFWPEFRKIDLLRSIRVYQARKDEKKQENSYRVSKVINFLGVGKYGEKSEELGQLLPLKKQGVA
The following text describes a protein:
Function:
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MATTQTAAAGGRPFRLRVRWDGGQARLDEKEIGAQTPLHELLAHLATITGIPAQEQALRSGYPPTLLNLSNPSQPLEALGLRPGDTLTVASTTPAPVQTDSHPPAPDSTPAPSRSTVPADAVGGDPNGECILRRVVPADNSCLFRSIAYLVSPEAAGQPAAQVSNAIVQPLRQTVASRIRAEPERWTEATLGRSPDDYCKWITSLDAWGGGIEIALLAEALNVQIGAVDIQTGRVDMYAQDRPNDSAILLLYDGIHYDPLVLSPIGATAPEDFCLRRIDIADVDRVARLAQQLSAALRERHQFTDVGSFTLRCLVCRTKLRGQSEAQAHAKQTGHTNFGEVD
The following text describes a protein:
Function:
Thiosulfate sulfurtransferase which catalyzes the transfer of sulfane sulfur from thiosulfate to cyanide.
Subcellular Localization:
Mitochondrion.
Sequence:
MFSKTLSVSRLLMTRSFYSSTVVKNVSIFDFEKVYNLSKRPTGDKSTVLIDVREPDEFKQGAIETSYNLPVGKIEEAMKLSDEEFSKTYGFSKPVFEDNVVVYCRSGRRSTTASDILTKLGYKNIGNYTGSWLEWSDKIKSK
The following text describes a protein:
Function:
Central component of the spindle assembly checkpoint.
Subcellular Localization:
Nucleus.
Sequence:
MSDTPSSPFIEHPETPRKALFSSNRPSPVRSTHATPSLHGTPSTASRFSRTPREDVIGLKKTISQLRYDLEALKQEQQVAQILQEEKERELEAKHKKELDRAEQAESDQVFLFNKQKELSDENRTLKEELRSLQSQHEADGRELNHELEGLKDLLNDLQSENRALVSEMNYKIEDYEHRIKAASTTTDDLLKEVENRGTALTEAKMNVVKFEQLVESLKGESLDLKQSAKDLEAVEQTKSQLSDQIKYSRELEAKVSALTVRVEAAESAQQLSQVYEEDLSSMKGKLKNMEGLRQQLAEQQLQILVHEENSAKWKAYLEKSDEFKTVEEVVTALNKARMEKASLLERAGSGVNDETRSTAEAYARLQERVTTLESELQLAQNQLKTEKKKVATSIRQHTLAANEAKFLREQLKAYDDEEVTAAGADVKQGRIDELEKLLEAVKNEKSVLEGELKEARSEQGCTVAAGTKRPRADDSVSSEVISEYTRKLQTLQQEFDEVSVEARLLAKTKEALEARLESLEKSQESRVRILELRENPTSRHEAVKQSMLDTLKAENEALMGKNENSKSVPQASLERKQLELQGVRDKLASTEKSYQRLKEVFSVKSLEFREAVYALTGYQIDILRNKKVKVTSMYAQSDEDSFTFLPDPNHKGQFAGVIDSPLTDEFSNIVDYWVKDKKDFPCFLAALNLELYERKENNGNQAS
The following text describes a protein:
Function:
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
Sequence:
MRDADAALTGLRERFEPPGDGVALTAATLGAHGDDAAATLQRAVDQWRARGDGAWTNAEPAWADYAELLGDRVAGLIGAKPSECVAAGGSPRTIARRLVAGFRRAADGDTVVVPEGATGATGEQPASPVVTVAADSAGAITPAAVADAVTDDTAVVYLPSVRPWTGQLLAVDAITEIAHSHGAYVGFDLAHSAGVVDHTLHRSGVDFGVWSSHRYLNAGPGAVAGLFVHDDNADISAPARTAWLTPDDPPSTGAAASHAAEWQHTPVDVYAAAPLFGALDVGTAIGITELRAHSVALTWYVIGLVDAHVPDCHVRSPRAAERRGGHVALTHPNAESVARALDARGVAVDVRPPDVLRVAPSPYYVSHEDIWVAVDELETVLSTAAHEQPPDTDTNPP
The following text describes a protein:
Function:
Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MKRKRGKDKALAADDGVSTSKGPAPLSSNWLELQAALGKQVKYKKKTKPSKETPTAVASAGVSKGEKDEAVSLQPTSSDFSVTKVLAMDCEMVGVGVEGKRSALARVTLVNIYGNVVYDKHVRPQEFVTDFRTQVSGVRPRDLRKAEDFWTVQKDVAELIKGKVLVGHALHNDLKILLLSHPRKDIRDTQRYKSLRSDNGRVQALKHLAAEHLGASIQEREHDSIEDARAALFLYKKFREDWEKGLKQRRMGSKVAIASGEEKSRSSR
The following text describes a protein:
Function:
Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
Sequence:
MDDLNKKYLIDLHQHQNSSIEVLREFAEVNEVPIVDRLTLDLIKQLIRMNNVKNILEIGTAIGYSSMQFASISDDIHVTTIERNETMIQYAKQNLATYHFENQVRIIEGNALEQFENVNDKVYDMIFIDAAKAQSKKFFEIYTPLLKHQGLVITDNVLYHGFVSDIGIVRSRNVRQMVKKVQDYNEWLIKQPGYTTNFLNIDDGLAISIKGE
The following text describes a protein:
Function:
Promotes the exchange of Ras-bound GDP by GTP.
Sequence:
MDKINNENDKINISIKAPIGNIEDNNNNSNNNSNNNSVSNSNNNSSISINSGSNTPTNSKNRGIKIFDLDDPFTSKRLSGFFSPESLAELSKLQLNDTDNNDNLTTTTTTTTTTTTTTTTTNTITSKNNSPNTSPLLSSTTISSITSGAPIKKRFERIPSGLSHVTNHYDDDDDDESSSSEEDFDSTELVCRPNKTSSTTATTTTTTTSVSPLTSSFVMRRPSSPSPPPSCSSPTLSPSLSATRRLSGNLVKVATDSDNQSLEPCNNKTIVDNNDNDNDNNNNHNNNNNNNNNNNSTEDISIKPICNKTFLDLDEKIYLKIFGYLFAEDLCSINRVSKHLCNIINNQQLWKDLFSIYIKIYSEPSDIYIWDEDLYSIYNNNNNNNNNNNNNNNNNNNNNNSNISNNNNNINNSNGNNNPYFTGGVSNSSIGAIGGSIGSSAGSNIALKLRSNTSIPIIERGRSNTIAMPTPTFINEINMLNSNNSVNNNNNISNNNTINSNNAGVIINPSGTVNNNINNINSSNSINSSSSSGSNINLSNNNSSTIHGSYISSNLILNSVLRKFTPTTSVPSTNEVTDFIESCHHFPSKLLICKLVQRYLVPREFQRHLSDIDWVKMVERPIQLRVGKLLKKVIDQKKVNFDYGTMLILRSFIRGYIQSTSDMAKGLIVGLQKKQVLKVFDISRVSDILLIKIFRNLDSIKDLSVCQRVSKRWNKAIAISSLWEQLYLNYRKKLHHEGDINIWDDPSLHTVEYLYEFFDQIQPSPQQQQQQQQQQQQQQQQQQQPQLQTNESNNNNEDIKQNDNNNNNSNNNGLNNLQKLIEENLEGSNLSNGGNSGSSFSPFNPLSGSNGGSSFGPFGSGGGGGSNSNIGGSSNQLNSSSGGGGSGFLAMASGGSSVSSVTSTPSTISTNCTPTGGSTTNSPNFQSPMVSSSTVLPPPIPFSPNLSSPRSMSISLSSPPPLPNKPPELKLPDSSLSPNSSFNNNLSSTSISIPSTPTTTPSSSLLTFIPPNTTSTTTTTSTTNITSTTMPISAATTTTTTTTSTTSTIIQPIQPIPPVNNNGSQSDLSKISDLNANPNTTTTTTTNTIESSSSSSSITNNNENIIEPIKSPQPSMINVQKLMNLNQLVDKLTSITVATEISEVNACLATYRTFISTSQLVEKLFQRYHIPRASNIKSILDWKQRIETPIQVKVCKVFKKLIDDHFDDFNGTIIELFKVFLLHIIDKQSPLTNHLIRSFSRKLSGENGSTGSVIGITGGKSSRKGGGSGSGSGSGGGSGSSIIGGAVGGTIKASQSKIGRMMSVRKAQQFNDIISLPAEEIAKQLTLIEFEIFGKIQSSEFLNQSWAKEKTFHLAPNIRASIDRFNTVTKWVCTIILKEEKIRTRTKIMSKLLKVAKNLRSYSNFHTLMAILSGLNEIHIYRLKFTQQELKPKIQKISSELQTLMSVEGNHEAYRTELSNVDPKQSCIPYLGVYLKDLTFIQDDTNKKGDGINIKQSLNLYNILKTIQNFQKNPYSFEEFPKIKETLLNLPVWTEDNLYRVSMQREPRNCKRSDLI
The following text describes a protein:
Function:
Nucleus inner membrane protein involved in meiosis. Plays a role in regulating nuclear envelope (NE) morphology and nuclear integrity, particularly during spindle pole body (SPB) extrusion or insertion through the NE, and perhaps during karyokinesis.
Subcellular Localization:
Nucleus inner membrane; Multi-pass membrane protein.
Sequence:
MDNWEDPNFELRNLRVIDLKKILHESGVSFPVNARKIEYIRMVDRIRKNKLSSGPQHLLSHLQKEENSNTSKASSSEDEIAPKYLYPSSPSKSTKKPHNETEPLLSPQFIDKPSNIETPVKIESPHVSQNNTFQSYSELSPNVETSLTMKTPPAHASTPKFRSHKSHRVAVPMSFMDSSALHTSPAFSERLKLLSSSNNFSPQLRSPKISHRLQTSATSSPLQHKRPFTNVPERVSRDIEFAPLDSARPSESSSPYSEVDSAEEDDELFQNYVLQQTRKESKLWSFIKKVFHDIKYANYRLLHNLRAFPGISAISSSYLVHIFMILLGVVAAIFLALLREKMFTAGFCDSGASGSSASILGISFPSLCRTCPPNAICPSPNYVECKPGYVLYEPWYSSLGFWPSKYCVSDTSREESVNIFREECLSVLRSWNAILHCSNNSSDLLERNMSYNAHPYVADNLNISSDHISFPSKPFALGLLHDTLLERKSPTLGLEMFEDLFKASLAVLSETNEVVMDSKLICYDSWAGIPLRCRLKQQLIKFVWRNKVFLFGILALSGVIFKLINFFRTRSIVAKYLPSASRFCVESLKRQKANYQMSRSQEPVIPLIEMHDILFHGNGPLEQIHMTKATARTLWEAIVERVEQVGSVRTRESEVDGEWTRVWEWVGTNTLDFQTDRSFINTTSPLRE
The following text describes a protein:
Function:
Involved in the biosynthesis of the antitumor antibiotic sibiromycin. Hydroxylates the C5 position of the peptidyl carrier protein (PCP)-bound 4-methyl-3-hydroxyanthranilic acid (4-MHA or 3H4MAA), leading to the formation of the fully substituted anthranilate moiety found in sibiromycin.
Sequence:
MRILVNGGGPAGMAFAMFAARSGRGDEITVRDWTGPGDTYGFGVILPPAAVEVFRDAEPDLADELNSHITAWDRLSVHRHGRTASIPAPRLGAMDRRTLLKVLRRRCAERGVRFEHGAVDPALGDHDLVVAADGARSVTRRHRAAAFGTTTREIGPAYIWLGADRALEHLRFLVAETPDGPAVAHAYPYSPDRSTFLVEADGAPPPAVLAEWFAGPLGGARLLENRSRWSRFQEIHNRTWSAGNVVLIGDAAHTAHYSIGSGTRLALDDARALADALCAQPRLADALKGYEDARRPIVEHTQRIGRLSATWFTRLPDVPMERLLDDLATRGGQISWRDLATEGSGAVPVRG
The following text describes a protein:
Function:
May function as positive regulator of plant growth.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing VQ18 show stunted growth phenotype.
Subcellular Localization:
Nucleus.
Sequence:
MEITQYQSFHEGSSSRVSMNRNSQVISKIKPKIRIIHIFAPEVIKTDVKNFRSLVQSLTGKPAPGEAKTGKKRAKSRITTPQEPVCDDHQPVNRLSGFTGLLANGGNHQVKEEWGSGDQSTSNTNTYFDLEGLIQDVGEDYFSSFPMRSSSSSQVEGFIFNNNNNNNNNNNNNNNNNTNFDTKAHNSS
The following text describes a protein:
Function:
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
Subcellular Localization:
Cytoplasm.
Sequence:
MREKLTVIKVGGKIVEEEATLLQLLNDFAAISGHKVLVHGGGRSATKIAAQLGIESKMVNGRRITDAETLKVVTMVYGGLVNKNIVAGLQARGVNALGLTGADMNVIRSVKRPVKEVDYGFVGDVEKVDASLLADLIHKGVVPVMAPLTHDGQGNMLNTNADTIAGETAKALSALFDVTLVYCFEKKGVLRDENDDDSVIPEITRAEFEQYVADGVIQGGMIPKLENSFEAINAGVTEVVITLASAIKDNEGTRIKK