The following text describes a protein:
Function:
Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme.
Sequence:
MTFQLPEDFDSHIIQERIGPTTEILVKSDFPLTAYEPKVQVPFQTLPGQCPRRIEIERRRRQYLKLDINQLLAAEGIDSNLLMPRHPDPKNMQTIEQKNDPLFPIYLPLQVFDDEEFDCRTPEEWLAMGLEPGCPNRKPVPGKALLPTDDFLGHEDPKSIQLIYEWNHVGVLDYDEQKKLYLVHKTDERGLIRDDMGDPILNGGMTPEGRALLLPCQFWIPRIQLLFCAEDPRVFTQRVVAANLLRKKTEALLLYNLYVDCMPTEGLRVLSEQSLEMIKQRTMSTPRMRKGAIVLEQLVTLAKEANLDYERTMNKINFDRIVAAKPETFSYVTLPDKVEEKVPERGLVDMPEYPFLDQKEAFTFVSLLTRTEVITALGKVRAECNKVTAMTLFHYTLSKFGRLEEFEQIQSQMFSQVQMFLKDSWVSTLKVAIRSSLRDMSKGWYNLYETNWEVYQMSKLHKLMELIKYTLQDSIRFLVQDSLVNFTQFILDACYSVLGCPEDLVWGSDLINSPYKPRKNPLFIVDLVLDQNGSHYSTPFENFESSLLNLFDKGILATHSVPQLEKFVMEDIFVSGIPLLESVGLHEPLVEDLRKSLCNAIEKALIPLQAYSKEFTKHLELNNNDIKTFLREYEAKCPPASEVREVVKSHLKEKEILDNSLPSNIIIGPFYINVENTKQNLSKKRKALATSMLDILAKTLHQEVESVCEEFRYISRKIYEKPNSIEELSELREWMKTIPETLVALEERIVKVMDDYQVTDEFFYNLTNDDFNDKWAASNWPHKILGQIELIRELHQEEEEKFHKIQMMDQNNFLEKLDGLQLMVAGFSIHTDITRAHEIANEVRRVKKQLKECQQLAMLYNNRERIFGMPITNYDKLFKMIKEFQPYWDLWTTASDWLRSSESWMNDPLSAIDAEQLEKIVIESFKTIHKCVKQFRDVPACQMVAIDIRGRIEDFKPYIPLIQGLRNPGMRNRHWEMLSENINMNVKPKANLTFSKCLEMNLQDHIEAISKVAEVAGKEYAIEQALDKMEKEWTTVLFNVLPYKETETFILKSPDEASQLLDDHIVMTQSMSFSPFKKPFESRINTWETKLRLTQEVLEEWLTCQRSWLYLEPIFSSEDITRQLPVESKRYQTMERMWRKIMKNANENREVINVCADQRLLDTLRDCNKLLDLVQKGLSEYLETKRAAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLQITHMYSGEGEEVQLSFFIYPTGNVEDWLLEVEHSMKASVHDFIERAIRAYPETPRPEWVLNWPGQVTIAGCQTFWTKEVSEALEAGDLSSRLFPQLGTQLQDLVALVRGKLSRMQRAVLSALIVIEVHAKDVAGKLIEENVVSVNDFEWISQLRYYWTKDDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASSGAWACFDEFNRIDVEVLSVVAQQITTIQKAQQQRVDRFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYTMIAEISLYSFGFSDAKVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPTMNEELICLQAIRDVNVPKFLQDDLKLFAGIVSDLFPNIKEEKIEYGILDQAIRQACLQDSLKDVDGFLTKCIQLYETTVVRHGLMLVGPAGSGKTKCYKVLATAMTSLKGQPSISGGVYEAVHYFVLNPKSITMGQLYGEFDLLTHEWTDGIFASLIRVGAISSDTDKKWYMFDGPVDAVWIENMNTVLDDNKKLCLSSGEIIKLTEPMTMMFEVQDLAVASPATVSRCGMVYLEPSILGIMPFTECWLRKIPGLLMPFKDKYVSLFEKFLEESIEFVRGSVKEVITSTNSNLTMSLLKIMDCFFSPFVPKEGVKKIPHEKLVRVGELVEPWFIFSLIWSVGATGDAQSRAAFSLWLRQKMDLEEIGLLFPVDGLVFDYRLDDCGISSPDDAEEEEDENKQVSWVKWMDISAPFTMVPDTSYSNIIVPTMDTVQMSFLLGILLTNKKPVLCIGPTGTGKTITIFDKLLKNLPLEYITHFLTFSARTSANQTQDLIDSKLDKRRKGVFGPPLGRYFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKMIGSFKNLVDINFVCAMGPPGGGRNAITPRFTRHFNYLSFIEMDDQSKKRIFSTILGSWMAGFLGEKSYRDPVPGAPDVADLNKPLVSATIQVYATITSQLLPTPAKCHYTFNLRDLSKVFQGMLMAEPSKIQNKVQLLRLWYHESCRVFRDRLVNDEDRIWFDKLMESKMLLWNTSFSEVCPYQPILYGDFMMPGTDSRIYELITRRRMQIVIEEYMEDYNQVNTAKMKLVLFMDAMSHICRISRILRQSLGNALLLGVGGSGRNSLTRLASHMAEYECFQIELSKNYGMAEWREDVKKILLKAGLHRLPVTFLFSDTQIKNESFLEDINNVLNSGDIPNLYSPDEQDQILTSMRPLIQELGLQPTKANLMAGYTGIVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPSEALESVASRFLKEIPELDTTNEVMDGMIQVCVRIHQSVAKKCIDYLQELARHNYVTPKSYLELLNIFSTLIGEKKQELKTGKNRMKSGLDKLLRTAEDVAKMQEELETMRPLLEEAAQDTLITMEQIKVDTAIAEETRNAVQAEENKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGDKPGTKVDDYWEPGKGLLQDPGKFLEGLFKFDKDNITDVVIKSIQPYIDNEEFQPSAIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALREAQEDLDETQKILDAAKTRLREVEDGILTLQAKYRDCLSKKEELEMKCDQCEQRMGRADKLITGLADEKVRWQNTVTNLDYLLNNIFGDILMASGFVAYLGPFTGQYRISLCESWLDQLTKYGVPHTEEPTLIGTLGNAVKIRSWQIAGLPNDTLSVENGVITQYSQRWTHFIDPQGQANKWIKNLERDNGLDVFKLSDRDFLRSLENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGTTVLKLGDSVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPGLEDQLLGQVVAEERPDLEDAKNQLIVSNAKMKQELKDIEDQILFRLSSSEGNPVDDVELIKVLEASKVKAGEIQVKVRTAEQTEKDIDITRMEYVPVAVRTQILFFCVSDLSNVDPMYQYSLEWFLNIFLSGISNSERADTLKKRIANINKYLTFSLYTNVCRSLFEKHKLMFAFLLCVRIMMNEGNIDEDEWRYLLSGGTIKDVIPNPAIEWLSDRAWRDILALTNLPNFSALAEDFSFYLEDFQRIFDSAEPHREILPGKWEEHLDQFQKLLVLRCLRGDKVTNAMQDFVAINLEPRFIEPQTANLFAVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLTAISLGQGQGPLAEAMMQSSMERGKWVFFQNCHLAPSWMPSLERLIEQINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVKANLLKSYISLNDDFLNSCQKALEFKCLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYEDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLIPDYTYSESGIYHQINPTYDINGYLQYIKSLPLNDIPEIFGLHDNANITFAQNETFALLSAIIQLQPKSTSTGGHSREAMVEEIAGSILKKIPEPINVHHVMMKYPVLYEESMNTVLVQEVIRYNKLLNVITESLKDVLKALKGLVVMSSQLELMSTSLYNNAVPEIWKGKAYPSLKPLSSWVMDLLQRIEFLGNWIQEGIPPVFWISGFFFPQAFLTGTLQNFARKCVISIDTISFNFKVIEQSPSELFERPEIGCFIHGLFLEGARWDPELFVLAESRPKELYTEMAVIWLVPVPNRKPPTKGFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTKKGQRHWIKRGVALICALDY