lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
Sequence:
MKYEGWPDEGELVVGKVDDIEDFGVFVDLEQYQDKRGLVHVSEVASGWIKNVRDHVNEDQTVVAKVLGVDESAQQIDLSLKDVNDHQHSDTIQEWKNEQKADKWLTLAFGEDMADDQFRRIANGLLADFGSLYDGFEQAAIHGHEALADTALEDDEIDAIVETARDNVSVPYVTVTGYVSLQSPDGDGVDTIKDALQAAEGNGEVPDEVDLDVTYVGAPEYRLRVQAPNYKTAESALEAAGDRAVDSVTAHDGSGAFHRERQLDDDA
The following text describes a protein:
Function:
Non-processive alpha-1,3-D-rhamnosyltransferase. Catalyzes the transfer of one D-rhamnose (D-Rha) residue from donor substrate GDP-D-Rha in alpha-1-3 linkage to both GlcNAc- and GalNAc-diphosphate-lipid acceptor substrates. Is also able to transfer D-mannose (D-Man) to these acceptors at a lower level. Nucleotide sugars GDP-D-Rha, GDP-Fuc, UDP-Gal, UDP-GalNAc, UDP-GlcNAc and CMP-sialic acid cannot act as donor substrates. Only compounds with a diphosphate as the aglycone group can act as acceptor substrates. No activity is detected with compounds containing a diphosphate mimic. Fluorescent undecyl-anthracenyl group-containing compounds, such as GlcNAc-PO(3)-PO(3)-AnthrU and GalNAc-PO(3)-PO(3)-AnthrU, are also good acceptor substrates. Involved in the biosynthesis of the common polysaccharide antigen (CPA), also called A band, which is one of the two major cell surface O-antigens of the P.aeruginosa lipopolysaccharide. Involved in susceptibility to antibiotic colistin.
Subcellular Localization:
Cytoplasm.
Sequence:
MRVLHFYKTYLSETVGGIEQVIFQLCESSGSWGIDNHVLTLSSDPHPPVVPFGGHVVHRARLDLQLASTGFSLSVFKQFRELAAEADVVNYHFPWPFMDLVHFLTGMNKPSVVTYHSDIIRQRVLLKLYRPLMSRFLHSVDRIVAASPNYFSTSDVLRQYREKTRVITYGLDKDGYPKPATQRLEHWREKLGPRFFLFVGVMRYYKGLHILLDALQGTDYPVVIVGAGPLQAELYAQAAALGLRNVHFLGRVDDEDKVALLQLSYAMVFPSHLRSEAFGISLLEGAMYGKPMISSEIGTGTSYINIHGETGLVVPPSQPAAFRQAMRWLWEHPQQAEEMGRNAEARYRQLFTAEEMGRRWSELYRELLEEKASSRYVKAAR
The following text describes a protein:
Function:
CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Subcellular Localization:
Cytoplasm.
Sequence:
MLCLSQRLQVKFRAYFAIIILIAVQLVQPTMSCKNENCSQRLHRSLKLNKFTNKMTVKLLDTYKASQGDSTDLICEMQMDNVPVSTISGQTESERILSMYSHLKAFLPHLKTVMEQQRDLDPPTNPVTEGINSLITHVRHMAVRVNCLLQILQPNIPIPEPAERPTGIPPAQNIFQQKVYGCIVLTRLQQLLSQAVQEQKSLKGKTCRRTKKNYS
The following text describes a protein:
Function:
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MRLTAKQITWLKVCLHLAGFLPLLWLFWAINHGGLSADPVKDIQHFTGRTALKFLLATLLVSPLARYAKQPLLIRTRRLLGLWCFVWATLHLTSYALLELGIHNLALLGSELISRPYLTLGIISWLVLLALTLTSTQFAQRKLGKRWQTLHNVVYLVAILAPIHYLWSVKILSPQPVIYAALALALLALRYRKFRQWWR
The following text describes a protein:
Function:
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
Sequence:
MFSGSRGRGRGGSRSSRTTAAIDPDRTVRETDIDASVARLSAISKNYIQDEYAELLMSCQYGGSQEMMIRRPPWVNIGTHHRTYLIDELVSSFLGPPNHNQQEQEGEATTKQVLSLGAGSDSRFWRLKSRFDRENHNWPNGRWVETDLQPTVTTKIEKIVSSEKLRQVCGEDPIVLRSDDPDPTSSSDRPPTELHSPHYSLLSTDLRRPTELVAKLSGPDPTSTTSGHSLLCPETPTLIIAELVFLYLSPTHTHACLQSLVNYFRGPLMIICYEALDLEDNFSKMMVQNLATRGLSMAGFEANRSIDSQIQRFKEHGFTEIVCTDIKALRTRSFPGNQRDGDPDEEEGEGWKARWSAELDRIRKLEFLDEVEELELILLHYALSWARKNFILPSSSSSSTTNATTKSTVGFYLPKF
The following text describes a protein:
Function:
Cleavable component of the cohesin complex involved in chromosome cohesion during cell cycle. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by ESP1 and dissociates from chromatin, allowing sister chromatids to segregate.
Miscellaneous:
MISCELLANEOUS: Present with 1040 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin except at centromeres, where cohesin complexes remain. At anaphase, it is cleaved by ESP1, leading to the dissociation of the complex from chromosomes, allowing chromosome separation.
Domain:
The C-terminal part associates with the head of SMC1, while the N-terminal part binds to the head of SMC3.
Sequence:
MVTENPQRLTVLRLATNKGPLAQIWLASNMSNIPRGSVIQTHIAESAKEIAKASGCDDESGDNEYITLRTSGELLQGIVRVYSKQATFLLTDIKDTLTKISMLFKTSQKMTSTVNRLNTVTRVHQLMLEDAVTEREVLVTPGLEFLDDTTIPVGLMAQENSMERKVQGAAPWDTSLEVGRRFSPDEDFEHNNLSSMNLDFDIEEGPITSKSWEEGTRQSSRNFDTHENYIQDDDFPLDDAGTIGWDLGITEKNDQNNDDDDNSVEQGRRLGESIMSEEPTDFGFDLDIEKEAPAGNIDTITDAMTESQPKQTGTRRNSKLLNTKSIQIDEETENSESIASSNTYKEERSNNLLTPQPTNFTTKRLWSEITESMSYLPDPILKNFLSYESLKKRKIHNGREGSIEEPELNVSLNLTDDVISNAGTNDNSFNELTDNMSDFVPIDAGLNEAPFPEENIIDAKTRNEQTTIQTEKVRPTPGEVASKAIVQMAKILRKELSEEKEVIFTDVLKSQANTEPENITKREASRGFFDILSLATEGCIGLSQTEAFGNIKIDAKPALFERFINA
The following text describes a protein:
Function:
A cytochrome P450 monooxygenase involved in fatty acid metabolism in the eye. Catalyzes the omega-hydroxylation of polyunsaturated fatty acids (PUFAs) docosahexaenoate (DHA) and its precursor eicosapentaenoate (EPA), and may contribute to the homeostasis of these retinal PUFAs. Omega hydroxylates saturated fatty acids such as laurate, myristate and palmitate, the catalytic efficiency decreasing in the following order: myristate > laurate > palmitate (C14>C12>C16). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MAGLWLGLVWQKLLLWGAASALSLAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLQILHTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRNADER
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MNPPGSLEALDPNVDEHLSTQILAPSVHSDNSQERIQARRLRIAARLEARRREALGEYLDGKKESEEDQSKSYKQKEESRLKLAKLLLCGTELVTNIQVAIDIREIHRRVEEEEIKRQRIEKLENEVKTSQDKFNEITSKWEEGKQKRIPQELWEMLNTQQLHCAGLLEDKNKLISELQQELKTKDDQYVKDLKKQSDDICLLLERMEEQVKNVMKTFREELYNIEKAFEVERQELLASNKKKWERALQAHNAKELEYLNNRMKKVEDYEKQLNRQRIWDCEEYNMIKIKLEQDVQILEQQLQQRKAIYQLNQEKLEYNLQVLKKRDEENTVIKSQQKRKINRLQDILNNLRSKYAKQIKQFQEENQSLTSDYKRLVMQFKELQKAMRHFALIDDAKFREIWLMNEEEAKDLIARAFDVDRIIHTHHLGLPWAAPDFWFLNNVGPISQQPQKSATQIVEEMLMRSEEEEAEEATSEPESYLDLPKQISEKTTKRILMLLCDESGFLIESKLLSLLLPLEQNECYLLRLDAIFSALGIESEDDLYKLVNFFLKYRAHRLSSSLQIKPCSQASVEKASMEETSTRSELELAEQTEMEGEKEESLVEGEKEEEEETPPSPWVIHPNDVLKILEAFVMGLKKPRDSRAPLRVQKNVRDNSKDSEYWQALTTVIPSSKQNLWDALYTALEKYHLVLTQRAKLLLENSSLEQQNTELQALLQQYLNSKINSELQVPPTQVLRVPTK
The following text describes a protein:
Function:
Involved in biosynthesis of the epicuticular wax. Plays a role in very-long-chain fatty acid (VLCFA) biosynthesis and is required for C28 fatty acid elongation in stem. Despite its classification as a BAHD acyltransferase based on sequence homology, CER2 does not seem to share the catalytic mechanism of the members of the BAHD family.
Subcellular Localization:
Endoplasmic reticulum. Nucleus.
Sequence:
MEGSPVTSVRLSSVVPASVVGENKPRQLTPMDLAMKLHYVRAVYFFKGARDFTVADVKNTMFTLQSLLQSYHHVSGRIRMSDNDNDTSAAAIPYIRCNDSGIRVVEANVEEFTVEKWLELDDRSIDHRFLVYDHVLGPDLTFSPLVFLQITQFKCGGLCIGLSWAHILGDVFSASTFMKTLGQLVSGHAPTKPVYPKTPELTSHARNDGEAISIEKIDSVGEYWLLTNKCKMGRHIFNFSLNHIDSLMAKYTTRDQPFSEVDILYALIWKSLLNIRGETNTNVITICDRKKSSTCWNEDLVISVVEKNDEMVGISELAALIAGEKREENGAIKRMIEQDKGSSDFFTYGANLTFVNLDEIDMYELEINGGKPDFVNYTIHGVGDKGVVLVFPKQNFARIVSVVMPEEDLAKLKEEVTNMII
The following text describes a protein:
Function:
Possible regulatory or functional link with the histocompatibility cluster.
Sequence:
MPRKRPFSAKQKKKQLQDKRERKRQGFQDGVRSSSNSRSGSHDRHEEHTDTSDSESFSLQVRRINQQPQIRKPGEQGYDPNRYRLHFDRDSKEEIERRKKIAREKILEPVPEAETEVDIEDIYKTGSVLDFPKRPPWSYQMTKEQLLAREEKCFRDYLENIYTTFQPSQLSYFEHNLETWRQLWRVLEMSDIVLLITDIRHPVINFSPALYDFVTKQMKRNLILVLNKIDLAPPALVVAWKHYFKSRFPEVHVVCFTSYPQHDQDPSAVFKKRRKRRKGWSTAMGPDQLLSACESITAGKVDLSSWKEKIERDAACARLPLEDSEDSEEDDESAAVLVEHQTDVAMEAGGFCQEIYKDGILTIGCVGFPNVGKSSLINGLVGHKVVSVSRTPGHTKYFQTYFLTPTVKLCDCPGLIFPSLVDRKQQILSGIYPISQIQEPYTSVGYLASRIPIQALLKLRHPDAEHGKPEPPWCAWDVCEAWAEKRGYKTARGARNDVYRAANSLLRLVVDGRLCVCMRPPGYTAHKAMWEHHIETTEIAALQEAHGHDGRRSSGEEEEAEGEEEDEISSSGEEEDEEKDRDADEEAEEEEEMLSAPKSGPSQPFPSRKGKQFAGRNLFALLGEDEC
The following text describes a protein:
Function:
Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLSTSPSRSFKNKFRAAFWPVHNYELGKFIPISALMFCILFNQNILRILKDSILISEISAEIAGFAKVYCVTPVAALFVIIYAKMINHLTFEKIFYYLSAFFISCFILFAFVIYPNIHIFHVHPDTLSDWMNKYPHFKWYISLVGNWGYIVYYSLAELWPNIFYVLLFWQFTNELTTTEEAKRFYTLFSLFGNSSLILVGFLMMNLSSEDTIIKKFISISDSKITLVQVSTTIIAIVAIICCLLVRFISKYIFTNPLFYHKTKSSRSTAQRMGLIKSFKYIVKSKYLWLLLICSAAFGFAINLVEAVWKAKIKELYPTVNTYAEFNSLYILWTGVAIIVMTIIGNNVMRMHNWFVAAVISPVIIMVTGVLFFGLIVFDQQILSLFDGAILMSPLALAVSIGGIQNILAKGTKYSIWDTSREMLYIPLDDELKTKGKAAVDVISAKVGKSSSGLVQSIIFTLVPNATFTSISPILMVVFTFVCFAWIYAVRKIYFEYQKIA
The following text describes a protein:
Function:
Defense against chitin containing fungal pathogens (Probable).
Subcellular Localization:
Secreted.
Sequence:
MVPQAKLVVASLILTSALIQTSEAVGGIATYWGQYTETEEGSLAEACASNLYSYINIAYLNIFGEGRYLSLNISGHCSDCTFLGEEIKACQSQGVKIFLSLGGPYGDYHLTTDGDADRVAEQLWSSFLGGSKSTGVYQPLLGDVELDGIDLDIQIGPPEEYDVLARNLKDLTKDRTRPFYLSAAPKCSAYNDSDAYLWTAVETGLFDFVWVKFYNDTSCQYNNDTAAGLDAFYRSWYDWTVSLAEGNKLLIGIPASNETDNSPLGGYIPSDVLNDQIVSVIMTSSKFGGVNVWNRYYDLKTNYSSSIILEYVNSGTKYLPLRTKFMYQNA
The following text describes a protein:
Function:
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular Localization:
Cytoplasm.
Sequence:
ISLVIPEKFQHILRVLNTNIDRRRKIAFAITAIKGVGRRYAHVVLRKTDIDLTKRAGELIEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYNQVLANGLDNELREDLERLKKIRAHRGLSHFWGLRVRGQHTKTTGRRGRTVGVSKKK
The following text describes a protein:
Function:
Transcription factor (By similarity). Binds to DNA sequence motif 5'-CTGTTTCA-3'. Regulates expression of a class of small RNAs, known as 21U-RNAs, perhaps acting redundantly with fkh-4 and fkh-5.
Subcellular Localization:
Nucleus.
Sequence:
MQSNDENIYFPANQYVNAGQYSPLQQSFSQNSQYDLFDGFAEFGFLEQVPTTNMHSFSQSTQMEQNCLPNVNNSTRKRKAPGQNEQATVKRRQIGIEKWRLPSRSVVQPSADISDLRRPPISYVALCALACRNAPDMKITPAGVYAFILHHWRYYRYANENWKNSVRHQLSSKEHFDEETFQPDPSNQTVRRKFYIVKNPNMIRQNLISDADFDFFRKDSRGIEFYQKMFAGQIGLPRSLFYQIIGNEIPFLAGPENSSMFYQLLGMGKVVGYLETRYFREHYRSEHAATEPKYEEDYANFTEKIPSNAENLMSYGAATERNFQKFDFTDEEIELFHLNISSYHSVQKTCKECNLPNWCTPSVGDVETYVFGRQVPMPVNTPVILQQFETVAEQEGIRNNPLEEQKTTKDPRDISVLEALA
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQFSHQHSSDVHFIVSRERSSPSTCTMNLVLPLLPNGQQLLSVAFGIFKCFGFIPFPFDCCTFALTPCSNVRSLLHLPILQVSFYLTLFCIIMSNRVNFFFTGLQILSLNDIIKYGTLTLSVFAIFIDTVLQRNTHRLVWEKIALIRLSARKVYVERFTRHYLWKFYGYLAVCAFLEAQVLYLAWDDPSALAYWLVIMILHAFLRLRHLFHMFFIDILKIHLQKLHHDLVDAGEYMADLVEQPQDTAVFRAMYAQSVDRLLSLKSVYGQLWELSDCINRNFGWSQICNFTGNFVQLSCDLYWLYMSMKWFEATEYKVVIVITLLPSTSIIVLLLSSAESCLGVAASLQSALLDIPMGNDSTFRKIIYRFGLQIAQQRIRLTAHGLFEINYSLLKMFGTGITTYMIIFITFSKDIKLEDIDDE
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEFFEVEIDLSELEQSTVSDEEDIEEQADQELNEDEDDEEDEDEDEDDDDDDDDDDDEDEDEDEYYKSKKTPKTSKTLHTCSQCGKNYKHISSLRIHLLSHTGEKPFHCDQCEKTYSTLSGLKIHQVVHFSERPYSCSVCGRSFSRLDSCKQHQKTHDKVRDHVCTECGKSFTTFSQLKQHQIIHSGLKPFKCSYCDRSFTQAGNRKSHERIHTGEKPHRCTECGRSYKDLTGLKNHMRVHSGEKQYVCEHCGKGFNSVSNMRYHLRVHTNEKPHVCSVCGRGFSLLVSCTLHEKIHTGEKDKVCDDCGKSFVTNGQLKRHRVVHSGKRPYQCSYCEKSFSVSAHLKIHMRLHTGEMPYRCADCGESFRHSNSLAIHRRKHDQPEQSPPVHTVS
The following text describes a protein:
Function:
Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9.
Miscellaneous:
MISCELLANEOUS: Present with 8970 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Mitochondrion membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass type I membrane protein. Note=Cycles among the pre-autophagosomal structure (PAS), mitochondria and Golgi.
Sequence:
MVSKTWICGFISIITVVQALSCEKHDVLKKYQVGKFSSLTSTERDTPPSTTIEKWWINVCEEHNVEPPEECKKNDMLCGLTDVILPGKDAITTQIIDFDKNIGFNVEETESALTLTLKGATWGANSFDAKLEFQCNDNMKQDELTSHTWADKSIQLTLKGPSGCLKSKDDDKKNGDGDNGKDGDSEGKKPAKKAGGTSWFTWLFLYALLFTLIYLMVVSFLNTRGGSFQDFRAEFIQRSTQFLTSLPEFCKEVVSRILGRSTAQRGGYSAV
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MPISKLQQLSCCCCYDRVGGGGGGGHSSSKWSFKRLVALILAVFFVYVAVSAALSQHWQIQATSHEATFVPEVDADGHHHSDGKDKGEGTGTGISAAWSLLEKTRRAVQVAGGVPGTTLSDEDRQQWESVCPCHGRDQLRSLWLTRKEGSTKRAPREPSGELHLLFQEYSNLHRTCTRGGNMTHVLELYEQRANRYDCKFLVVEFGVYGVGNRLLWLASAYLYALLTQRVLLIDTRDTIHQLLCDPFPGSSWELQPHFPFSSAQRWPMPDAFFQVWDAWERDERSYKAYMAEMARKNGTEERRADDDDDASTGRSTTKRRSLLLSGPTIFDRAQANDGWSPNPRFFCDKDQQRLQQVQWMSLNSGCLYFLPDLFAMASFRPALEALFPDRDPLTHLLRQIALPVDSVWNRVFSVHRAHFQSSRKVVGLQVRFRDGGGMYRALNDMVNERITACGREHDIILNPAAGGGSRDEPPLVIFIASLHTGLQRHLREFYADLLERQMLTGKATLKLLQLSHAGFQAFDLDGDFQAFAEVVILSLSDEILTSPMSTFGYIAQAYGGLRPWLIDFDLHSSTSCRRGQSSDACYQMALSSFACPADPDINGKRLQDVVPYLRPCQDTDGLQLVPTSDM
The following text describes a protein:
Function:
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
Sequence:
MFSFKREIDFTGYSFIVPSVSVGNVPQLAADAVIETLQLEPIGLLWSPALVPIVGAPAFEHTGGSDAITTTAELYVSQEKKLLVLQLRAPLVGPLRQTFLDELSDFVRDRKFSHAILLSSCFSHEKFDIRTGPFRYVANEQYEAQSPDAAHLKDDRWTKHSGGVIHGGGFASKLLDGLTARQVPAVVFFMYVSEGDNTAEGLMLARMLNAISGERLLASERTDFRWPSSWKHLFGTAHPRTLY
The following text describes a protein:
Function:
Transcriptional regulator.
Sequence:
MSGDTMEAGLMRIGVSIPDALLTQFDEIIKKRDSPSRSEAIRDALISYITYYEWMEDIKGRRVGTIAVIYDHKKSGLSNSIINVQHHYSHLIKYSVHMYLDTDDCFELIVLDGNGQEITELAGSIIALKGVKFSKLTTVDPNKKI
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MSKPDNTVDSLCQEEKHLPEHHAQRARSGNGNANAVVPGGASPVRLACHINYRRPEGPAIGAIQDRGRFLKAPRKKNKNETAASVFQAPRCVLLAASSLSGRRGGTFVEGCTAPTLKSPSPQNRCAHALLFSITVFYIAVKFGLLTECKCHGVSGSCTMKTCWKSLPAFSQVGAYLVQRYQRARRAAPFYGRSRPHEPSTLRRRPAYLRLRKGRGPRTPGAGRPAAHGVARPKPRDLVYLHESPSYCERDPGRGSAGTVGRLCNRTSTGSDGCRLLCCGRGYDTHRRTRVWQCQCKFHWCCFVRCQTCSERTEEHTCK
The following text describes a protein:
Function:
Ribonuclease that plays an essential role in innate immune response by recognizing and degrading RNAs from microbial pathogens that are subsequently sensed by TLR8. Cleaves preferentially single-stranded RNA molecules between purine and uridine residues, which critically contributes to the supply of catabolic uridine and the generation of purine-2',3'-cyclophosphate-terminated oligoribonucleotides. In turn, RNase T2 degradation products promote the RNA-dependent activation of TLR8. In plasmacytoid dendritic cells, it cooperates with PLD3 or PLD4 5'->3' exonucleases to process RNA fragments and release 2',3'-cyclic guanosine monophosphate (2',3'-cGMP), a potent stimulatory ligand for TLR7. Also plays a key role in degradation of mitochondrial RNA and processing of non-coding RNA imported from the cytosol into mitochondria. Participates as well in degradation of mitochondrion-associated cytosolic rRNAs.
Subcellular Localization:
Endoplasmic reticulum lumen. Lysosome lumen. Mitochondrion intermembrane space. Secreted.
Sequence:
MAEARGALPGWVSVLGWGLALCCLCGAGPLWSGSHEWKKLILTQHWPPTVCKEVNRCRDSLDYWTIHGLWPDRAEDCNHSWHFNLNEIKDLLRDMKIYWPDVIHPSSNRSQFWKHEWDKHGTCAAQVDALNSERKYFGKSLDLYKQIDLNSVLQKFEIKPSINYYQLADFKDALTRIYGVVPKIQCLMPEQGENVQTIGQIELCFTKEDFHLPNDLYKQIDLNSVLQKFEIKPSINYYQLADFKDALTRIYGVVPKIQCLMPEQGENVQTIGQIELCFTKEDFHLRNCTEPEEQPSSGQEARLAREASTHGMMVCEDGPIFYPPPKSQH
The following text describes a protein:
Function:
Acts as a component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MDFLDYQAYGVPLTGTDDELLPEPASNLSLLAASGPSVSELNTSIQGDSTPPLLNTDSNFNFEGKDNLHERMEMYSELTVKLLPIQPGLVRDIFEDVTPQSSDFQHLLKKGNNVTSAVLVKRLSHVLNDMNHPNYQSDLQLKKALMILQDNQGVLGLDGSKLVRPDFLGSLSRKTLRSQLEKELLKDHLATLENFQPIARRIMRLRQPVKNIQEISEKVLDAQEAQNKSPLQDPLVSEVREKLEMLKLKKRVLVGIRESLTLNQLEDEQLRNGEIEDSYLDVLDKMMEIKERSTYLIAMNYEKAGKALLGNINQYLQLANKRIYNYLLGFLYDYESNTKTFGERNFEGDNVGLSLFQRCLVYLSNDLEYFNDFMKKVTSMRSKKLLDEFLIPFVIDNNEGRSIILSAHDPARYLGDVLAHVHSLLANEGDFLKSLFKYQEERMADMTQSIFQKNKDILQSLHVNMLNDIMSTLSNSVRIRLEQIVRFEEEATVTFDISQLLSLYKLMFTKQGMLDDNKLVKVFDDLAVLAKTKTMNYYTEFLSEAVKEEPEVTDLLPPKWLSKYLSDLTALFDKINGSSEQTGIVDKNFFTKLVKTPCESTFLKQAELCFPLAKKDRRVKFDLLVLEINGLDMIVSRLGPYRTNIFSDEYGSEVYDSLKRSLDTLLGQLEVHQTRNILESTGLELYYNLFNMIFPVASVQDPLDYDMYLSAQENQIMKLETIETNIAQKLSDYLPKALLDVQDTWLLYLASPKFADDIASRSFHVFANFYVVFKSVLLNIFPDDHQRINSIFIYSEEEVKMLLGIN
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MSLKRASLTFLSSLLVVSIATQFIVPSQPCLKYLTDLSSIITSSPIISTVIKYYLGDHPHDHHHHHHKKAKDSICDSFPPDFPPPDTNTTSIFCVDQSGCCNFTTVQSAVDAVGNFSQKRTIIWINSGIYFEKVMVPRTKPNITFQGQGLGSTAIVWNDTANSSHGTFYSGSVQVFSNNFIAKNISFMNVAPMPSPGDVGAQAVAIRIAGDQAAFWGCGFFGAQDTLHDDRGRHYFRDCFIQGSIDFIFGDGRSLYENCQLISIASPVPVGQKSIDGAVTAHGRASKDENTGFSFVNCSIGGTGRIWLGRAWRPFSRVVFAYTTMTDIITPEGWNDFNDVTRDQTIFYGEYMCSGAGANMTLRAPYVQRLNDSQASPFLNSSYIDGDQWLQPFL
The following text describes a protein:
Function:
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm.
Subcellular Localization:
Nucleus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MVICKFYQQGNCKFGSRCYNEHVRYNENRSRGQQRSQNDNYGNRGRNQNYVQPSRFDDSNRQHKSHTTDNYSSPFNRGGSNNTNFSSGSEKHHTQQSIDKFHWTSKSQSNRFNALAELEEPPLSSNTVQSEDHASMFKTISEDMALWPSSKMWPFSCYSYAKEKNCVEGLADIQPEEIRTLYYLYGLERYRNILDEVELIYTKRKEELRYMSEETKSSLLLQLGSSIESNPSAGLSIYSLYGPGTEFKSSSKVADVAAFPTQSTVNPTVTSTTTDLFKPAVAQSNPSALPPPSSSFIQPPPATGGALGQMFKTVPAAETKP
The following text describes a protein:
Function:
Forms a water channel that facilitates the transport of water across cell membranes, playing a crucial role in water homeostasis in various tissues. Could also be permeable to small solutes including hydrogen peroxide, glycerol and gases such as amonnia (NH3), nitric oxide (NO) and carbon dioxide (CO2). Recruited to the ankyrin-1 complex, a multiprotein complex of the erythrocyte membrane, it could be part of a CO2 metabolon, linking facilitated diffusion of CO2 across the membrane, anion exchange of Cl(-)/HCO3(-) and interconversion of dissolved CO2 and carbonic acid in the cytosol. In vitro, it shows non-selective gated cation channel activity and may be permeable to cations like K(+) and Na(+) in vivo.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MASEFKTKLFWRAVVAEFLAMILFVFISIGSALGFQYPVKSNQTAGAAQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISILRALMYIIAQCVGAIVATAILSGITSSLPDNSLGRNEGTEGLALGAWAWGAWDTVPTEACHPSPLQLASGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGFSVALGHLLAIDYTGCGINPARSFGSSVITHNFKDHWIFWVGPFIGGALAVLIYDFILAPRSSDLADRVKVWTSGQVEEYDLDGDDIHARVEMKPK
The following text describes a protein:
Function:
Replaces histones in the chromatin of sperm during the haploid phase of spermatogenesis. Compacts sperm DNA into a highly condensed, stable and inactive complex.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
PSTTSSKSPKRRAKSPRRKRTGPTVSDLILMAMSASSDRGGLSLAALKKDLKGRGYDVVRNKGRVLMAIKRLVANKSVVKAKGFYKLNKNPPTPRRRVAKRKKPKAKRAKRGRKRKAAPKKKSAKKKRKRRRRKSKSPKKARKARRAKSPRRARSPRRSKSPRKAKRRTTKTRRRAKK
The following text describes a protein:
Function:
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.
Sequence:
MTNYVLTRVANRTGIITLDRPKALNSLSLDMVRALTATLLAWRDDAAIDAVVIGSTSEKALCAGGDIRFFHEAGRATPQTGSPLLEDFFTEEYALNHLIHFYPKPYIALMDGVVMGGGMGIAQGGPDCGLRIVTERSRIAMPEVNIGLFPDVGGSHFLSHAPGRLGHYLGVTGVTIGAADAIYVGLADVFVPAAQLDALRALIEATPGAGLPAAIRAFAASFSAGAGELEAQRDTIDRHFGADSVAAVMASLETDSSPFAQKTLATMRQRSPLMMSVTREMLVRGERLGVADCLRMERSLVRRTFEHGEVLEGVRALVIDKDNAPR