lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Testis-specific protein that controls sperm transport and the timing of zona pellucida-evoked exocytosis of the sperm acrosome.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Multi-pass membrane protein. Nucleus.
Sequence:
MLVKRNKEGILNVTFKYYCPATSYILPQWQVFSVSSASEVPDWSNPLDVPELQSGINPVYLYIPPKSLAWGMYVFNFSLIFYVERNRTIAAVGSDIIYVNITKSDLQAVIAENPNITINFTDTLLLNGSGSSDPDSDNPLEGLIFSWYCTTEPKQYRGDKITVMSNKVCFPHYTNLRWPRASGPVLTIPPGTLKGGGVYFFRLVIRKGGRKGFVDRTVHVLKGPAPVASISCIENCDAVLVISDRFSLFLNCTNCSSSLDLYEWSLLSSNGSQVPFDWVRHTTTGKTSAYLTLKAFVFRNFSEAQFWISGHIASWSGHDLHFRHSFIINRVPQIGHCTIDPPKGVSFITKFVIQCQNFKDNNIPLTYKIIVSDLHGFGQISSVKENSLGAILYLGNQSTAPPSFLPVGMLANHYAMKIYVQVYDSLGAFSQVTLYSTVHSPTDEFSAKDVLDQLFNFTMGTNSSLSALLRNREFLPAGYLIFIAASVLNSLKPELTLQADKARLQEYLVNQTFVLPNSTLVEISQVVMSIAKLTQTTSGCTLMTQKLATVRIWQANQALQQSRQRDAHRHSEQIEIMSTGILTTLSNIIKMIVNYEVVDEPFYEMELLADTILDSKVPGNETTALTASSLNMYLRKTEKWDVTNAFGNKLTSRNYFNPTLNVSSVPSLPANAPISIMFCEFVDDPFPWLKYQENYSVEVVGFRMTGTTPSGSVTEIVPDIAEVYITRKNLSFAAFNLTMGPSNEPGKVEESLKRTTGEFSFEVDSSVVKEVLVHIVTEVTVIFTVLVYAGSQITPSALVATFFVPYDIPPVANQSDLFDSACTVKEARVVCIPPSLLQVIAQRSGSTECAMIIVLQAPRFVMVPSVKLVRIALFGAYCLDMYGIQSDWREDTCVLGEKTTWRRVHCICKHSGRARRQLDAIRKAGKHLQTHFLTAKVIVIPNAVDLRLEVIKNVTQNPVTLFTVLFIMLMYLILAFWALHRDGMDRFLRHQVIIILDNDPYDKVCYLITIFTGSRCRSGTRANVFIQLKGTEGDSDVHCLSHPYFTTLRRGNINSFLLTTKSDLGDIHSIRVWHNNEGRAPSWYLSRIKVENVFSRQIWLFMCRRWFSIDTSLDRTFPVTHPDQPLNKMDFFLIDSIYKLGRNHTWFSIFSSVVARPFNRLQRLSCCLAMLMASLLCNIMFFNLNPEDETEPEERRYIRSMMIGLESVLITIPVQLLVDFLFTYSQREPRVALEESAPRKNSLVPTSEHWEEYLEKWHALEMVDAQTKVALKLPPGKSARPQEASAKDPPVALHPHKKGQSKVSGPQKKKTKASNQNAKDNKNQNAQPVTMTEPSLIVSHHLEIDKKCRVNLPWYCVYLAWVLIFITSSIASFFIVFYGLTYGYDKSIEWLFASFCSFCLSVFLVQPSKIVFLSALRGNWRKYCKNLSWTSGYCYTEIKLHSRSFSPEELEKRHEQILQLRNSRMYQPLTEDEIRIFQRKKRIKRRAFLFLSYILTHFIFLALLLSLLALLRHTDSFYYNQFIRDQFSVDLSSVTKLADIYRWLNSVLVPLFHNEQDPTYLPDSSSKILGLPLLRQVRAKPGDKLCPPAKSFAHTGMEQEIRCHPSYGTDLEDTRNYTDLWNTVTKRAVDKNTNGFTYKPPEKVWAYFSHGLLHTYGSGGYAFYFFPKQQQFNSTVRLRNLQSSNWLDEKTWAVLLELTTFNPDISLFCSISVIFEVSQLGVVNTSISVHSFSLADFNRETSAEIYLYVAILIFFLAYVFDEVYVILQERASYVRSVYNLLNFALKCIFTVLIVLFFQKNFLATGIIRSYLSNPDDFIPFHSVSQVDHVMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQTALPGICHMALVVSVYCFVYMAFGYLVFGQHEWNYSNLVHATQTIFSYCVSAFQNTEFSNNRVLGVLFLSSFMLVMICILINLFQAVILSAYEEMKQPVYEEPSDEAEAMTYLCRKLRAIFRFLTFQPKDEDEPEFFVDMLYGQPEKNSRRYLGLKTRNINGKKMVYLVV
The following text describes a protein:
Function:
The ERF2-ERF4 complex is a palmitoyltransferase specific for Ras proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
The DHHC domain is required for palmitoyltransferase activity.
Sequence:
MVSPSSPESNDDDDLTNADSAITPATSTITTDSPTKSSFDDYQSLSSIRIPITRRITPSLSPQYEESNISTTTSATTTTTQQQHQQQQLQQQQQQLRQMSSLSASKIEQAKTDVLNNKKISFIHRFITNWLIMDPNLISHYNNTNTRRFKNYQIENQGQSNFIYFLGGRLHTIKTKYPINLITLSLIIIPGILYIIFELSWQWRNFSPIIVIIFLYIWIISIFHFFKLSTCDAGKLPKNIHLPKKLITITTTTTTTNDNEIDHRNNYKVMGSPPDEYFNTVTLPYWKTNNDNNDNTKISKLANAYHSHGVQVKYCGTCHIWRPSRTSHCNTCQQCILNHDHHCIFLNNCIGQRNYKFFLWFLLYIVIACLYLLIISILQLCHYKFASHKESEIITTFNQSIKTHPISLLLLIYSCLAICYPGLLLAFHIFLTSQNITTREYLNFVYKKPSKSTDGGDGTRGFVNVYNTHSIWENLYINWLGKSNGVSLTFPRDYYHQGDIRFANIEPLGTFTNK
The following text describes a protein:
Function:
One of the two proteins required for the splicing of precursor tRNA molecules containing introns. The ligation activity requires three enzymatic activities: phosphorylation of the 5' terminus of the 3' half-tRNA in the presence of ATP, opening of the 2'3'-cyclic phosphodiester bond of the 5' half-tRNA leaving a 2'-phosphomonoester and ligation of the two tRNA halves in an ATP-dependent reaction.
Sequence:
MTVKLPFSKIDSEEFAEAVQLELLDRLEAASQQTGKGKARKRNYVIWSNSGKMEADEQGREITGWKFNEWDYGKPKIVLASQSRGLFTRDNKIVVRGYDKFFNIGEVATTKWDWIESNVRGPFEVTQKENGCILFFSGLEDGTLLVCSKHSTGPVNTGDKSESPEVEPLDQASSQDLSEVNMSSASRDKGGSRSHSFAGLLHLKRHLKAKDLTLRDLALTLHELNATAVAELCDDEFEEHVLAYSAEEAGIYLHGLNLNTPTFSTYPSSRVREFAETFGLRHVKTLDFESISDLKKFLTLCDETGQYESKDIEGFVVRGKTGNSSSDFFFKYKFDEPYLMYRGWREVTRKLINKGRAEVHVTKHVHITNQYLDFVEPILAADKARADKFLDGHGIIGLRDEFLHHLGKSGKELSLQEDLGNLTLHDQVQHIVILPIATIGCGKTTVSLALHSLFGWHHIQSDNIKGTGVGRKMVQEGCRIIRDGDKEKKSQVIILDRNNSNLIERKQLFDEFDRLKCNPIFVCMSFVDGDDQVREKLARDRVLKRGENHQSIKVETMGMTRVDQIMRDRCKKMQGVNKAKEPDSRFDLVIECAVAANVTWQNLETVAKEMSKEYEWTVPKLPSREEYEAAFAAALNYAPTVSNLKKPQKLKPQYVAVAVCGVNEVLSKLGSPFLAQLTRDGRVQEEFHVTLAHVAEKKNNNYHKLLSEYVAKLLPHLESGVNPIEKVKFQIHVPRAIWNGRVFALEVDSVQGPQDETLLASIDHTSLDKFLHVTIGTAEEAIRPMESGPMVQNATHS
The following text describes a protein:
Function:
Part of the ABC transporter complex OppABCDF involved in the uptake of oligopeptides. Probably responsible for energy coupling to the transport system (Probable). Required for sporulation and genetic competence.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MIRVTRLLEVKDLAISFKTYGGEVQAIRGVNFHLDKGETLAIVGESGSGKSVTSQAIMKLIPMPPGYFKRGEILFEGKDLVPLSEKEMQNVRGKEIGMIFQDPMTSLNPTMKVGKQITEVLFKHEKISKEAAKKRAVELLELVGIPMPEKRVNQFPHEFSGGMRQRVVIAMALAANPKLLIADEPTTALDVTIQAQILELMKDLQKKIDTSIIFITHDLGVVANVADRVAVMYAGQIVETGTVDEIFYDPRHPYTWGLLASMPTLESSGEEELTAIPGTPPDLTNPPKGDAFALRSSYAMKIDFEQEPPMFKVSDTHYVKSWLLHPDAPKVEPPEAVKAKMRKLANTFEKPVLVREVE
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEESKLAEPCEWTEKSREHLMLQSEDPGYHTGEPSCSVPVQIHEALHMKEVPLHVTEQEMFEGNSSNPRDDSGFSSSSLLPQDLCSQLVPNAASTLPNVSPSDENEPSARGVRCGYEQTSKEGDNGNSAKSEHFLCPVCSNEYKAPSELKEHFKSHGHPRQDFSCWKVSCPFSTQDRKHFQAHLRREHCLTPVTCAHRTCRWLFPNSEEMNLHFRCHFPFHCNQCDFVSSNTKLFSQHKKEHHAEKDTRVGGGAAQSLQVPTSHPRQEIAHHSLEYNKKDQHESFPPQQTMKRAKTATQNGASKENPRCVTEGNSSTFPAFKNNSARVKNGHTVKNKNKAFKGDVENGKEHLFKTHMCPECKRCFKKRTHLADHLHLHFPDPNLQCPNCHKFFTSRSKLKIHMMREAGEKSHRCPLCDYSSVEKNALNRHMASIHEGVSNFYSDTYSCPVCQETFKLSQALKDHMKGHKSEPKVHLCFEQGCEQAMSDRKDFLRHLKESHGIQAVECRYHACSLLFKSREEMELHRKNHYAFHCQECDFVCSNKHTFRKHKKCGHPGKEELSCPFCPYKSYNPVEYSDHVGKMHANEKIHRCGDCDFATAHKRVLIRHMLLHTGEKPHKCTQCDFVCRDISYLSKHMLTHSSDKNYMCTECGYITKWKHYLNVHMRKHSGDLRYHCNQCAYRCHRADQLSSHKLRHQGKNLICEVCGFGCKRKYELQKHMQSKHSQTCQVPMYQCRYCNYQTKYKQALHNHENCKHTKHREFHCALCPYHTFSNTSLFFHKRKAHGYTPGDKDWLARYARMKQQISQSDLLFPYTSGSAKSSEEQVPSGVEQNSCLEPLVGSSKVDSTSNAQEAGCLQVADMTEASGDNNISVTDESLLATITLEPVETCNIGLEDFPVQIQLSASTELLSKETSEEALGACEDPLQAREELLCFTENLAVEDDINCGQEYEEEADPSLEDHDKMHESSETRAKFNQEPLLCDLNDKCTDLPVHVGANLDLQHNGIPLEVEESWAHVIKDGVQLTIVCESSELADNGTTEEETSASFHEDTEECSRPESMLRTLRKQDKDQAETLVLEGRVQMLVVQSRTPVYRCEKCSYITRKEGCMLQHSKSGCHARKSSLVCEECGASFKQQRGLNTHIIKKCPAILKRKKPSLQAVTSAEATISETGLEAPALDEGIMAESQASLTSEIRVEHVHPLSPCQDLILEELKGNISEKNNVLDKAQNRIIEFSSSASDDLGPDPLMTSGFQDREKYKFEQGKFRCLFCSFVCSRECTIICHVRDNCRELRGNSSETALRRHLRERSVSSVDEESQNTEEDEDHRKEFVYKIDGESRISCPSCPFTCSQNRAMRTHMKKGCLKPGELQCPLCSFRCMSSAALKRHKELHQKYSCNRAQLKCKQCDFTCKQPRCMKQHVKIRHEGVKPHRCQYCDFSTTRRYRLDAHESLHTGVGRISCDSCSRTFGTNSKLRLHQRRVHEKKPTHFCSLCDYSGYSQNDIARHMGSCHNGEPAFPCDVCQASFSSEAALKQHSLRKHQEKATHECLQCQFSCHSLATLRCHLQKHHLQLDCTICKQTFCRRQDLEEHRKSHFAHHCHLCQYAAKDRQQLVHHYAEEHETPAVPGAEQEMGLLCCPFCSFSCRHQLVYDHHVKGHGGIRVYKCSDCEYTTKNKQKITWHSRIHTGEKPYKCHLCSYACADPSRLKYHMRIHKDEKKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCEECDYCTNRADALRVHRETRHREVRSFICEQCGKAFKTRFLLKTHMRKHSEEKPYVCNLCQRSFRWPAGLRHHYLTHTNQHPFFCQYCTYRAKQKFQVVKHLQRHHPDQPDIAKGVGKDPFVPSAQTCDPAEAKAEQPQDCEGGILPGMNVQ
The following text describes a protein:
Function:
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.
Subcellular Localization:
Cytoplasm, perinuclear region.
Sequence:
MPAERKKSASMEEKESLLNNKEKDCSERRPVSSKEKSKDDLKITAKKEVSKVPEDKKKKLEEDKRKKEDKERKKKEEEKVKAEEELKKKEEEEKKKQEEEERKKQEEQAKRQQEEAAAQLKEKEESLQLHQEAWERHQLRKELRSKNQNAPDNRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKSIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLNFPPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPAILFKDNEKSQNKDSSKDDSKAHSYTLNKIERNRENENELMLEFESFLSLCLFINFCLTCPKPDFTLEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVRRKRPPLQEYVRKLLYKDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKESKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEKGPDLGNITVKMSCGFSFDKEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQSLGTPFNVNLESTFHVKPQLRHGERNTRESTDTNIPLYFKILNVPMSSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPNADLIFKTGGR
The following text describes a protein:
Function:
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSLLIDLKGKELEQEEVELLSHPLVAGLILFTRNFENREQIQELIRSVRQRVKKPLLITVDQEGGRVQRFRDGFTMLPSMQAFQETLSATEQVSFAKEAGWQMAAEMIALDIDLSFAPVLDLGHECRAIGDRSFSSDVKSAVNLATAFIDGMHQAGMASTGKHFPGHGHVLADSHLETPYDDRTKEEIFSGDLQPFQQLISQNKLDAIMPAHVIYSQCDSQPASGSKYWLKEILRKKLNFQGTIFSDDLGMKGAGVMGNFVERSKKALNAGCDLLLLCNEREGVIQVLDNLKLTENQPHFMARQARLQSLFKRRVINWNDLISDQRWRLNYQKLADIQSRWLDIQAAKND
The following text describes a protein:
Function:
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
Sequence:
MQQELTLLDRINYPAELRNIPLEKLPQICKEVRNYIIDTLSGIGGHFASNLGVVELTVALHYVFDTPKDRLVWDVGHQTYPHKILTGRKDKLNTVRKFNGLSGFPKREESPYDLYNTGHAGTSISQALGEAAARDLVKENYNVVAIIGDASIATGMALEAMNHAGHLKKDMIVILNDNYMSISKNVGSISNYLNNIITSHFYNHWKRVFYTFLKWLPIIGPATERFFKKVEKGFKDVLTPGGLFEDLGFGYIGPEDGHDVIRLVKMLEKVKKMKGPILLHIITQKGKGYDPAERDPIKYHGVTPFRKEDGAMDSGDTSKIAYSKIVGKMLAILTETNPKIAAITPAMIEGSGLKEYAEKYPEHLFDVGIAEQHSVAFAGAMTNGNIIPYMCIYSTFLTRAMDQLVQDVSLMNLPVRFVIDRAGCVGPDGETHQGLFDLGYLLGLPNMDVFVPSNGQDLIDALRWMEKYDKSPVAIRFPKSSVDLKTLDFYKETELQPGTFRVFKRGTDVALISIGSMIDEAKKASERLENEGLSVTLIDLVWLRPLGAEALNEELVNVRCFVILDESYIDSGVTGYLLNRMTRENLSKYIKTFGFPPEPIHHGERKEVFQKYRLDGESIAEQVAAVLKKNLIKP
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MARIRFQQTLIVLLSLAAFFRVGDAGCPIASLGRRSLKQAPVPAQPALIFGFYDLTCPTLNSIIDTRMRFWVLQDIRTPGKVLRLFFHDCFAAGCEASILLNSTAEFAAEKDAPISVTLDKFQVIEDIKSEVETACPGIVSCADILALAAAKAVELAGGPILVTETGRRDGVVSYLAGATASMPLSTQKIPDLEAMFVQAGLDINDLVILSGAHTIGEVHCSNFADRFDPAANSPFGDVSFGQELLAFCTRNGAGDIATLNLKTFMDLQTPNSFDISYYVNLIIGRGVMTSDQVLFNDLRTQPMVREFAANRTLFFESFQASMLKMGRLHVLTGTNGVIRKQCGVSVQLEISILRSLRT
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (By similarity). May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MGSKKHRRSRSRSRSRERARVVRHDRSPGDRHSRNRSPVKSSRRRARSDSGGSRSSGGSAGPSRQRGRESGHSSDSDRQHRNTHGRNRDSSSDDDYHDKKKQALKKKHNDEKDSRSRRRKSRSSSGSSTNSSRERNRSKTSRSRERERRRRQSRSSSRERHRDQRRRRNSPERDRDRRRRSQSRSSSSSSSDSDHGGKSTQGGSSSKEEKKKQRDLMKALETPEEKRARRLAKKEAKERKKREKMGWSEEYMGYTNADNPFGDNNLLGTFIWQKALEKKGIGHLSEKNLKDRNKHIQEENRRELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWAEQEDNFHLHQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLSVEMHEPYTFLNGLTVTDMEDLLEDIKVYMELECGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALYMNIESKIQAGGSNLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPIIKEEPEKEQPISREAGSGEEEAGSSSQQADREEDEDRRSRRTGGEEAERSGRSSPEEEKKGEEEEGEKDEAPEAVLTEEDLIQQSQAEYDSGRYSPTLLQNSELPLDTHIIAEEEDLQRLLLARRQMQVTGDASESAEDLFVRRAKEGMGGDEAQFSVEMPLTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPCPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MSLRLSRPAVRGLGSAIKSSRISSRSAALLVPSTSTSAFSTASPQRAAAAGHLRLPDDYVPPTQPPSARPVDTRKSQLLRTYTSMLRSTPLMLIFQHNNLTAIEWAAIRRELSLALSNVPVPEGAPDITSKIHLQVVRTRIFDVALKTVEFFDPSTVEPTTATTATGTKVPATYNHDLSKHAWKAVKEATKNTEAVEKTVYGQLAPLLVGPVAILTLPSVSPAHLGAALSVLAPSPPAFPAPSRKKNPGYYDLTCQSGLQKLLLVGGRIEGKAFDYDGIKWVGGIENGIEGLRAQLVHMLQSAGMGLTSVLEGAGKSLWLTMESRRSVLEEEQNPKKEGEGEEEKKE
The following text describes a protein:
Function:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.
Subcellular Localization:
Endoplasmic reticulum. Membrane; Single-pass type I membrane protein.
Sequence:
MGRAVPGVLWPVALMVCFCPTASPLLLFANRRDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAVQNVVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGETPRIERAGMDGSTRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSMARGATESDGPLASLTEKWPHGLCAMAYACNPSTLGGRGGQITRSGDRDHPVHTRCEEDNGGCSHLCLLSPREPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGENPKIECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNVAKVVGTNPCADRNGGCSHLCFFTPHATRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISLETNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDTNMIESSNMLGQERVVIADDLPHPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNCSPPTTFLLFSQKSAISRMIPDDQHSPDLILPLHGLRNVKAIDYDPLDKFIYWVDGRQNIKRAKDDGTQPFVLTSLSQGQNPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAMGVVLHGDRDKPRAIIVNAERGYLYFTNMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPLGLTVLGKHLYWIDRQQQMIERVEKTTGDKRTRIQGRVAHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPRCSCPVHLVLLQNLLTCGEPPTCSPDQFACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRLRCDGEADCQDRSDEADCDAICLPNQFRCASGQCVLIKQQCDSFPDCIDGSDELMCEITKPPSDDSPAHSSAIGPVIGIILSLFVMGGVYFVCQRVVCQRYAGANGPFPHEYVSGTPHVPLNFIAPGGSQHGPFTGIACGKSMMSSVSLMGGRGGVPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNMDMFYSSNIPATARPYRPYIIRGMAPPTTPCSTDVCDSDYSASRWKASKYYLDLNSDSDPYPPPPTPHSQYLSAEDSCPPSPATERSYFHLFPPPPSPCTDSS
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MGRQKGEAARSKARPSSSSLAASLLPSGATAVGFGGYVGSSRIDTSTPITQDTDSPFLDIDAELAQHLKRLARKDPTTKLKALTTLSTLLKQKSAKDVSPIIPQWAFEYKKLLLDYNREVRRATHETMANLVSTVGRELAPHLKSLMGPWWFSQFDAVHEVSQAAKRSFQAAFPVQEKRLDALMLCTDDVFMYLEENLKLTPQSMSDKAVALDELQEMHQQVISSSLLSLATLLDILTNEKHASENSNSELKHALKARSTAISHAEKLISVHKCFMEFLKSSSPAIRSAAYSLIRSYIKNIPHALNEANIKTLSPSILGAFQEKDPTCHSSMWEAILHFSRRFPESWNTLSVQKIVLNRFWSFLRNGCFGSRQVSYPALVLFLDCVPDKAITKDRFFLEFFQSFWGGKVHSESSNADQLVFFKSYCECFLWALQNAERYCEGLEEIHQFQHTLVDEVLLKLLWHDYLMVPVSRQLTNIDHIQEFGKCITEILSSLFSLNPNLLSSFCSTFEENCLNAFQQTENSENIEKIIRFLLLVDKHAVQKGDSWPLSYLVGPMLPKSFKLIQTIDSSNAVKFMVVAVSTFGPRKVVQEIVQEQNKDMNLKQFLQYYKDIFVPWCLQTNSSSILARLDLLLALLDDECFSEQWDSIVLHATGIHDSDHTLVLTLLMEKTREEIIKRKVDPKNWHHELLDSTALLISHSSPPFGSSNARFIRAVLGGITEEDQIILLSENTSILIFEEIFQKLQTFIQTSNFTWVRNANSLLNVEKHVTIKEHESVLEIATFSLEVLKGTFFRLKSLTQNPHLLPSILAVLFVIDWEHAMSALFYDGVDDVAYAKVVDRIGFCKSVHDYRCEMNTFFKNLSLDCRRVLGSMLVQVIRWGVVNEEKLDVDKVTSLGCLFVLEVLDSLCEGHIEEQMLLDELLKKDDSWPLWIVPDIKNRQRSGALKVDIVSSNASECHQMASFVDKLISKLGISRVIAGFELSTSSSNDVAPHHPHYPRAWLAAEMLCTWKWDSGSALSSFLPSLIQYTKNQDSCFTNNLFDPIVHILLDGALEKTIKKLSFFGIYPAPHDELESIEEVFVRSLVAILNTLFGGSIWGKEKAFGLFHLLVDRLFVGEDINLDCLKILPVVMSVLIGPLSSQDDESGNDENDPLKGNQIPDIIKGWIERILSFPPLNTWESGEDMEDWFHLVISCYPIRPTKGTQGFKPQRHITQMERNLLLTLLRNQRFHSATYNTVNKLPVVQMLLSKLTVVTIGYCWTEFNEEDWEFLLYKSRWWIESSVVSMEEIAESVNDIITGTSNSNSNSNSGVPENLRRIVSDFDSIPLKLATNALIAFSMFRGLIRKQTTENENENENDLNPLRAEKFDAIKDRILEGILRLFFSTGATEAIAGSYSSEGCLVISSSRLDDGHFWELVGSSVVDSSVLARDRAIKSFEIWGLSKGAVSSLYSILFTEKPVPCLQYAAYVILSSQPVSDSAFVMEDSSSSLDETEKDPHDLSLTVRLRDEVSRFLEKPSEILYSDLVAPERVNVFLAWSLLISHLLSSSSSSSRTREKLIQHIQDSSNSTILDCIFQHVPLELCTVNIKKKLSELPEGIAEVAAAATRAITDSSVLFAVESLWPVGPDGMASFAGAIYGLMLTTVPAYVRGWFNDIRDRTTSSAIESFTRAWCSPPLITNELSQIKKANLCDENFSVSVSKSANEVVATYTKDETGMDLVIRLPASYSLRPVDVECTRSLGISEVKQRKWLLSMMSFVRNQNGALAEAIGIWKSNFDKEFEGVEECPICYSVIHTANHSLPRLACRTCKHKFHSACLYKWFSTSHKSNCPLCQSPF
The following text describes a protein:
Function:
Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
Subcellular Localization:
Cytoplasm.
Sequence:
MELTIKSRNGKISDRQRAHIEEKLSKLERYLHGITSITVEVQHEQQRNAGEVYRVQTTLVAEHGVILRAEERAPDLYAAIDEVQEVLQRQIARYKDKYWRRSREQRRAPNGLTPAEEVAIAEAEAAALATPTEVGSEARVIRTKTFRLRPMFVDDAIEQMELLGHNFFVFQDAETMQVSVLYRRRDGNYGVIIPEVG
The following text describes a protein:
Function:
Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III (CIII) or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation (By similarity). Mediates early complex III biogenesis (By similarity). Participates in regulating the levels of electron transport chain proteins, and therefore energy supply, in response to changes in energy demand (By similarity). Also involved in the first steps of cytochrome c oxidase complex (complex IV) assembly.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MFTRAQVRRILQRVPGKQRFGIYRFLPFFFVLGGTMEWIMIKVRVGQETFYDVYRRKASERQYQRRLEDE
The following text describes a protein:
Function:
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (By similarity).
Sequence:
MTVHELDAAGIHDPALRAAYTRCRGLNARHGKTYFLATRLLPVDRRPAVHALYGFARWADDIVDDLDTPATPGERARALLGLEAQLEAGLRGARAAEPVIRALADTAARYTIDHRHFTDFLSSMRSDLTVGGYASYEELGRYMHGSAAVIGLQMLPVLGTVVAREEAAPHAAALGVAFQLTNFLRDVGEDLDRGRLYLPTELLAAHGADRDRFEWSRSTGMPDSRITDVLRAAAAHNRAVYRAALPGIAMLAPVSRPCIRTAFVLYSGILDAIEADGYAVLHRRAVVPRRRRAAVALDGLVRAVAVRTVCRRRADAVDASRSAELSRPRTAGGPAPVRREAV
The following text describes a protein:
Function:
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MRTNVRLLAYRLLRKYEKEKFISREDVDSVLSFLDDRDRRFFKELVWGVVRKEELLDWYINQLLKKKDIPPAVRVALRMGAYQLLFMNSVPDYAAVSETVKLVKNENFKKLVNAVLRRLRTVPEPKELHLVYSHPEWIVNYWRSFLPEEAVLRIMKWNQEPLPVMLRVNSLAATKEEVIKILAEEGTEAVPGKHAPFSLIVRKLGVPMNDSRVINDGLASVQGESSQLVPFFMELRPGLRVLDTCAAPGGKTTAIAELMKDQGKILAVDISREKIQLVEKHAKRLKLSSIETKIADAERLTEYVQDTFDRVLVDAPCTSLGTARNHPEVLRRVNKEDFEKFSEIQLRMVQQAWQLLEKGGILLYSTCTVTKEENTEVVKRFVYEQKDVEVIDIRDKMKEFEVEGIWDGYGFLMLPDETITPFYISVLRKMG
The following text describes a protein:
Function:
Binds to RNA with repeat sequences CUG and CCUG.
Subcellular Localization:
Nucleus.
Sequence:
MFDENSNAAGTTPVASSLAATPNANLMSQVFNVKDSRWLQVEVCREFLRGQCARSDQECKFAHPPPNVDVQQGRVTACYDSIKGRCTRENPKCKYLHPPQHIKDQLLINGRNHLALKNLLSAQINQGGNQMINPMLALQQQAAAVNLLPNTQMYPQYYNGMMYQQVLPDPYAAAAQQLQTAALLGNVGGLLSAQSAAAALVANSSTQPPTPSPLLRLQRKRALEEDTSNGNDRTAAAHTQLLSLAAGAVPVKRPALDKNGAMLFSPAAPQTPQFNPYLLQTLQGYVPTVSCEYMQPPPF
The following text describes a protein:
Function:
Epoxide hydrolase involved in the biosynthesis of cucurbitacin and mogroside tetracyclic triterpene natural products (e.g. siamenoside I and mogrosides IV, V and VI). Cucurbitacins have cytotoxic properties and exhibit deterrent taste as a defense barrier against herbivores. Mogrosides are nonsugar highly oxygenated compounds used as high-intensity zero-calorie sweeteners; they also possess pharmacological properties such as regulating immunity, lowering blood sugar and lipid levels, protecting the liver, and acting as antioxidants and antitumor agents. Catalyzes the hydrolysis of aromatic epoxide-containing substrates, such as the conversion of 24,25-epoxycucurbitadienol to 24,25-dihydroxycucurbitadienol.
Sequence:
MEGIQHKFINVNGLNMHIAEKGEGPLVLFLHGFPELWYSWRHQIVYLADHGYRAVAPDLRGYGQTTGAPLNDHTKFTIPHVVGDLIGLLDAITNEGEKVFVVGHDWGAIIAWNLCMFRPDRVKALVNLSVAFMPWNPNGNIAEILRRDHGDDHYMTRYQKPGEIEAEFAKIMSLETFMKKILILRDPGPLLIPKGKGFLHSPPGVPVTLPPWLSEEDIEYFASQHEKAGGLTGGINYYRALYLSWELTSAWRGAKVMVPTKYVVGDMDIAYYMLGADNYVTSGEMKKDVPLLEEVVVMEGVAHFLNQVKPDEINKHIIDFIQKF
The following text describes a protein:
Function:
Essential RNA-binding protein. May be required for circadian repression of eclosion. Also essential for nurse cell dumping during oogenesis, the process whereby the cytoplasmic contents of nurse cells are transferred to the oocyte late in it's development.
Subcellular Localization:
Cytoplasm. Nucleus. Note=The precise location within neurons varies according to the type of neuron, being cytoplasmic in CCAP neurons and nuclear in the CNS.
Sequence:
MPGAGTFKLFIGNLDEKTQATELRALFEKYGTVVECDVVKNYGFVHMETEQQGRDAIQNLNGYTLNEFAIKVEAAKSRRAPNTPTTKIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRNYGFVHLDCVGDVQDAIKELNGRVVDGQPLKVQVSTSRVRPKPGMGDPEQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGGYRDRMYGRDPYPPPPPPPPFLRDRIMDGFRDYDYYDRRFEDSRDLYERRYQTSRMRDFPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPPPPRSSNGMSRYGSPTPHGYEDFSRDAFDERMISSRGMRGPSPPGRRYAPY
The following text describes a protein:
Function:
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
Subcellular Localization:
Peroxisome.
Sequence:
MARLSAARYGKDNVRVYKVHKDEKTGQQSVTEMTVCCLLEGEIDTSYTQADNSVIVATDSIKNTIYIKAKEHPVNPPELYASILGQHFLDKYAHISAAHIDVTVHRWTRMVIDGQPHPHSFLRDGQETRNVEATVTRDGITIKSGIVGLQVLKSTGSAFHGFVRDEFTTLKETWDRILSTDVDAGWTWKKCANLAAVQDGVERFDAAWEAARNITLKTFAEDESASVQNTMYKMCEQILDAVPETEKTNYSLPNKHYFEVDLSWHKGLQNTGKDAEVYAPQSGPNGLIKCEVSRS
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MVVLSASILSNRGSKPLVSRQFVEMNRLRVEGLLAAFPKLMGHSKQHTFVETDAVRYVYQPMENGMYLLLITTKASNIVEDLGTLRLLAKVVPDVTGSVTEHSINEHAFEIIFAFDEVLTTGGYKEDISPSTIRTNLEMHSHEEEMALMLKKSKEDAAKEQMQAQAKAIKDRQMAALRDNLMRQYQSDNPYAHLGKSSVPEPDAPKVVAKGMKLGGVGGSKKKDSLMAAMASEDNLMGGFGGGAGGSAADPFGLGLGGPAAASAALPAAPSAPATIVVEEKMTVQMTREGGIESSEVKGTITYTANTEAGSMANVAVNKAIYSAKCGNGWSFATHPKVEKKDYEQNGILSLKGGKGFPLNRPVGILRWNYSGEDSAPFTVNCWPEDAGSGTITVNMEFELQRMDAVITDVNILLPLGTTDPPAIESIDGQFKHDPNTGMMCWHQDVIDANNSSGSLEFSIAGSDEDVFFPVQIAFSSQSLMCPIEITSLTNAQSGAPIPNNMTVRVVPESYQCV