lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Polyglutamylase which modifies both tubulin and non-tubulin proteins, generating alpha-linked polyglutamate side chains on the gamma-carboxyl group of specific glutamate residues of target proteins (By similarity). Preferentially mediates ATP-dependent long polyglutamate chain elongation over the initiation step of the polyglutamylation reaction (By similarity). Preferentially modifies the alpha-tubulin tail over a beta-tail (By similarity). Mediates microtubule polyglutamylation in cilia axoneme, which is important for ciliary structural formation and motility. Polyglutamylates olfactory cilia, necessary for the regulation of ciliary structure and beating.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=CEP41 is required for its transport between the basal body and the cilium axoneme.
Domain:
The flexible c-MTBD (cationic microtubule binding domain) region mediates binding to microtubules. It is positively charged and becomes ordered when bound to microtubules: it interacts with a negatively charged patch on tubulin. The presence of positive charges in the c-MTBD region is essential for proper binding; Gln-174 is the main determinant for regioselectivity, which segregates between initiases and elongases in all tubulin--tyrosine ligase family. A glutamine residue at this position is found in elongases TTLL6, TTLL9, TTLL11, TTLL13, TTLL10 and favors glutamate-chain elongation, whereas an arginine residue is found in initiases TTLL2, TTLL4, TTLL5, TTLL3, TTLL8 and favors initiation.
Sequence:
MGTPAERSVSEVCRCEPDPGLEGEGWGSDTHAEPSNTPIPLPVANKKKKRKKKLWINLTNCKYESVRRAARRYGIREAAEGEDWTLYWTDCSVSLDRVMDMKRYQKINHFPGMNEICRKDLLARNMNRMLKLFPKEYNIFPRTWCLPADYSDFQAYTRAKKHKTFICKPDSGCQGRGIYLTKSSKDIRPGEHMICQVYMSKPFIIDGFKFDLRIYVLVTSCDPFRVFMYDEGLVRFCTTHYTEPTVSNLEDVCMHLTNYAINKHSENFVRDEDTGSKRKLSSFKKHMEDMSYDTEKLWTDIEDAIIKTLISAHPILKHNYQTCFPNHASGSACFEILGFDVLLDRRLKPWLLEVNHSPSFTTDSRLDREVKDSLLYDTLVLINLGACDRRKITEEEKRRVKERLQQNRSREARNEEPRQSQAASMELMQKYEAKHMGGFRRIFPRDGGEKYEKYFQHSSSLFQETAASKAREECARQQLQELRLKQEQKERDKKGSRKQDLQGESAGEKVKPRKSQPPHKTSNSLPAMLELSSVREETPVSLERIEKEEAERVRELQQRETLLLNMGVVNQVRQLLQSANRLTQCINHSHEQASFPPHCRHDHKLDTLAEISWRQKNIYSTMQHQILARNRPSLPNVHSQTLQNRKPWPSLEHGLLQPVQTQAAALKHYGLEEMVASNAEEQANLIKATSAQQIPLTINGSFIWRQGSLSSSLAESRARATMLAMPPLGPGRLHRPTIFHDPNSLSIISTPAPLVPRPHLSHDLRKAPRRVLPHEHSL
The following text describes a protein:
Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSGAGSGYDFNPITFSPDGRQFQVEYATKAVEKDSLALGVKCKDGILLAAEKNLTSTLLTPGGNPRIFWINDSIACATIGHRPDCYSIVEQSRNRAETFTSNFGIKITVPQLASEVSQQFHLAHYYQAYRPFGCTVIFASYKDDALYAIEPSGAFYGYFASCFGKNSNLARAELQKTEWKNITVREAVPEVARIIKSLHESQFKKWEIEMFWLCEETNGRPQKVPEDVFQSRFVNENPQN
The following text describes a protein:
Function:
May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLSILAKKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQAPDPNLEWTQISTRYLREQLAKISDFYHMASSTGDGPVPVPPEVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIRPMDDDLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSPNLLAAHSPHMMIGPNNSSIGAPSPGPPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKSANPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSSSLAGSSLPVFQNVLLRFLDTQAPSLSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTRPRSPVGENADEHYSKDHDVKMEIFSPMPGESCENANTSLGRRMSVNCEKLVKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTETGVGDEGQKARKNKQETFPTLETVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLGKILSDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSNHVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADAEPGARMTCRLLLHLFRAPQACFLPQATGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNSVSSLKNDDFTMRGLRCDGNADDIWTASQNPKSCGKSISIETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSADLNNSSNSGMSLFNPNSIGSADTSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQDDIKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRRVIKYEEQHHLLLYHTHPMPKPRSYYLQPLPLPPEEEEEEPTSPVSQEPERKSAELSDQGKTTTDEEKKTKGRKRKTKSSSRVDEYPQSNIYRVPPNYSPISSQMMHHPQSTLWGYNLVGQPQQPGFFLQNQSLTPGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMMQPPSLHAITSQQQLIQMKLLQQQQQQRLLRQAQTRPFQQGQPGDQAALFAAQARPSPQLPQYPGLQQAQTMPQGYTMYGTQMPLQQTSQQQAGSVVLSPSYNSRAYPAAHSNPVLMERLRQIQQQPSGYVQQQASPYLQPLTGSQRLNHQALQQSPLVGGGIDAVLTSAHPNLPSVPLPQDPMRPRQPQVRQQQRLLQMQQPQQPQPQQPPQPQQSSQSQSQTLGLQAMQPQQPLFPRQGLQQTQQQQQTAALVRQLQKQLSSNQPQQGVTPYGHPSHF
The following text describes a protein:
Function:
Acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development.
Subcellular Localization:
Nucleus, nucleoplasm.
Sequence:
MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESLQLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTGSRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDELEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAENASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPVEK
The following text describes a protein:
Function:
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of a SNZ isoform.
Miscellaneous:
MISCELLANEOUS: Present with 195 molecules/cell in log phase SD medium.
Sequence:
MTVVIGVLALQGAFIEHVRHVEKCIVENRDFYEKKLSVMTVKDKNQLAQCDALIIPGGESTAMSLIAERTGFYDDLYAFVHNPSKVTWGTCAGLIYISQQLSNEAKLVKTLNLLKVKVKRNAFGRQAQSSTRICDFSNFIPHCNDFPATFIRAPVIEEVLDPEHVQVLYKLDGKDNGGQELIVAAKQKNNILATSFHPELAENDIRFHDWFIREFVLKNYSK
The following text describes a protein:
Function:
Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.
Sequence:
MFKRAIVGNVYRIPARSFFGVSKPQSYEISKILHGSPKQVYDIVSQVDQYKTFVPFVEDSFISQRNKDELPTRAGLLVGWKDIVERFECDLICVENKEVTAKSLQLDLFDNLETIWKFHEHGGNKCKVDFKLAFKFKSPIYDKLSSLFAPQVSEIMIGAFERRLKQIKLNESMKKYQKPKL
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MNRLLQQTASRGSLAVRASSTVTTKPPAPNQITKQNAQFDKVTHTGQAWDQSDYRLQRFDISKKSVNPNVAMYLIDQRPPEDCGDKRIVWCDGGHPALGHPKVYINLDKPGVHACGYCGNRFYNSHATKGEDMKIQHLNC
The following text describes a protein:
Function:
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MPSRQKITYGFPQKEIPTDAASLNKTLEQIGIRSREMLNLTVKELHPTKQIHTTSIYACEKVEIPADNSCLFASISYLCTGSTSHATEDRFHCVSVIKNNPTKYTEATLVSPNKEYCAWLSDMRHWGGYIEMEILSEKYNVEICVLQVENNLIVPINGAQSKKRIYLLYDNIHYDALVFKAHTPPEVRKIVDASDEEATIQAKELMNIARAAGGYTNVKTMTYKCTICNKILNGSKEAHDHSAKTNHMDYVQIQNL
The following text describes a protein:
Function:
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
Sequence:
MAARTGQEARTGLGSRTVTRNLSASGERNDGNAMMSDEIRSEVRRIVPALTDDRYKGQSGKIAVLGGCAEYTGAPYFAAFAALAVGADLSHVFCSTSAAPVIKQYSPDLLVHPYFMQTADLLQQMRASPPACGSTGDAQQDAAAAQAAAAAAHVAEATAEVEGWFNRLDCLVVGPGLGRDPLLLDIARSVILRARACKIPLVLDGDGLFLVAREPDLVAGYTNCVLTPNLNEFRRLASTLGVSLHGPNNDRSSKLVEVTAHLRGPTLVSKGPVDAICDGKVTMICNASGGAKRCGSQGDILAGTIATFIAWTLAFLDSARQSAEVEVVILPEINPMVLASYGACLVTRTAAAYAFASRKRAMVASDMLAQLGSAMEMLFDSAGGAGGGAGAGVATGGGGQGQGIMQAHTAAGGGGGGS
The following text describes a protein:
Function:
Required for calcium regulation. May regulate calcium accumulation by a non-vacuole organelle. Also regulates the activity of CSH1 and SUR1 during mannosyl phosphorylinositol ceramide synthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSTTLLWFSSVIGYVIQTKCLSNIQSKKEISVGPNGTIATPETNGDNGNSSSLTFYLTFMYFASWLLLVPASRLWEKMRPMFVSDSDSNRNSQFDNNNSGSVTNEDVDTFSHVLDDPQPRIPAQQQKQKIISVATFKYVAKLTVLALIMIVADLTYNMALSLSPAFDVALMQNTAIFEIVTLLYGVCGISRKNYVFRNFLIMMNAVIGILIISYTKATCDMLAGKLSVNPNTGELSDPFLFDRLKGALICGLGALIMGPFAVLWNRWFCSNISKNENSAVVLVKQSTHMALIGIIGMVILLPFIPKFPSRESVESISLFYNDKSFWFSLLGSIIFGSLPSLISILELNRKAPAEYLTTCNLGAIIFMGLAEWVCEPTQTTIVRWEVIGYIMLTVSLLVLSVTLGEGKYHH
The following text describes a protein:
Function:
Utilizes UDP-glucose as the sugar donor and catalyzes the formation of O-beta-D-glucosyl-cis-zeatin from cis-zeatin. May regulate active versus storage forms of cytokinins and could have an impact on seed growth.
Sequence:
MVRGNNQPLDPVAVVAVPFPAQGHLNQLLHLSLLLASRGGLQVHYAAPAQHVRQARARVHGWDEDALLSIRFHELGISSYVSPPPNPTADSPFPSHLMPLFEAFTADARGPLAALLGKLSASCRRVVVVHDRINAFAGEEAARLPNGEAFGLHCLAVSTLVGKMDADHRLMRENGLTFAPIENCATKEFVEYANRARPLAQISPGVGILTNTCRALEGDFIDVVAEDLAADGKKVFAIGPLNPLLHASASKQRPHECLDWLDKQPPASVLYVSFGTTSSLRAEQIEELAAALRGSKQRFIWVLRDADRGDIFAEAGESRHEKLLSEFTKQTQGTGLVITGWAPQLEILAHGATAAFMSHCGWNSTMESLSHGKPILAWPMHCDQPWDAELVCNYLKAGILVRPWEKHSEVITAKAIQEVIEEAMLSDKGMAVQQRARVLGDAVRAAVAPGGSSRKDLDDLIAYMTR
The following text describes a protein:
Function:
Secreted protein cleaved by KEX2 in 8 similar peptides (ECE1-I to ECE1-VIII). Stimulates biofilm formation; [Candidalysin ECE1-III]: Acts as a cytolytic peptide toxin that directly damages host epithelial membranes, triggers a danger response signaling pathway and activates epithelial immunity. Polymerizes in solution to form membrane pores to damage epithelial cells. Induces calcium influx, oxidative stress, mitochondrial dysfunction and ATP depletion in host cells, leading to epithelial necrosis. Serves as a danger signal that potentiates the immune response, and more specifically IL-17 response. Induces cytokine/chemokine secretion by host (especially CCL2/3/4, CXCL1 and S100A8), neutrophil recruitment, and promotes mortality in zebrafish and murine models of systemic fungal infection. Mediates distinct epithelial inflammatory responses through p38, EGFR-ERK and TREM-1/DAP12 pathways. Acts as one of the hypha-derived drivers of NLRP3 inflammasome responses in primary macrophages and thus contributes to the capacity to induce maturation and secretion of IL-1beta from primary macrophages. Stimulates mast cells by mediating cross-talk between signaling pathways activated by the dectin-1 receptor and MAPKs. Enables escape via the gasdermin-mediated pyroptosis, as well as a cell lysis pathway associated with macrophage extracellular trap formation termed ETosis. Acts as the main hemolytic factor of C.albicans. As an exotoxine, also promotes alcohol-associated liver disease or oral carcinogenesis.
Subcellular Localization:
Secreted; [Candidalysin ECE1-III]: Host cell membrane; Single-pass membrane protein. Note=Candidalysin is delivered to the invasion pocket in which the hypha is tightly surrounded by the host membrane, to enable the full damage potential of during mucosal infection.
Domain:
The N-terminal alpha-helix of peptide ECE1-III allows insertion of the toxin into host epithelial cells membranes.
Sequence:
MKFSKIACATVFALSSQAAIIHHAPEFNMKRDVAPAAPAAPADQAPTVPAPQEFNTAITKRSIIGIIMGILGNIPQVIQIIMSIVKAFKGNKREDIDSVVAGIIADMPFVVRAVDTAMTSVASTKRDGANDDVANAVVRLPEIVARVATGVQQSIENAKRDGVPDVGLNLVANAPRLISNVFDGVSETVQQAKRDGLEDFLDELLQRLPQLITRSAESALKDSQPVKRDAGSVALSNLIKKSIETVGIENAAQIVSERDISSLIEEYFGKA
The following text describes a protein:
Function:
As a component of the mitochondrial small ribosomal subunit, it plays a role in the translation of mitochondrial mRNAs. Involved in mediating interferon-gamma-induced cell death. Displays GTPase activity in vitro.
Subcellular Localization:
Mitochondrion.
Sequence:
MMLKGITRLISRIHKLDPGRFLHMGTQARQSIAAHLDNQVPVESPRAISRTNENDPAKHGDQHEGQHYNISPQDLETVFPHGLPPRFVMQVKTFSEACLMVRKPALELLHYLKNTSFAYPAIRYLLYGEKGTGKTLSLCHVIHFCAKQDWLILHIPDAHLWVKNCRDLLQSSYNKQRFDQPLEASTWLKNFKTTNERFLNQIKVQEKYVWNKRESTEKGSPLGEVVEQGITRVRNATDAVGIVLKELKRQSSLGMFHLLVAVDGINALWGRTTLKREDKSPIAPEELALVHNLRKMMKNDWHGGAIVSALSQTGSLFKPRKAYLPQELLGKEGFDALDPFIPILVSNYNPKEFESCIQYYLENNWLQHEKAPTEEGKKELLFLSNANPSLLERHCAYL
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as non-selective cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MNKALLLMLFMVLYNGASSNGIGVGATATTARPEVVNIGAIFTFDSVIGKIAKLAIALAVEDVNSDPENLNGTKLTLKMQNTKSSDFLGIIEALQFMENDTVAIIGPQFSATAHVISHIADELKVPLLSFAATDPTLSPTQFPFLVRTTRSDLFQMTAVADLVDYYEWRDVIAIYVNDDFGRNAIAALGDKLAEKRCKISYKVPLNPKATKDEITNALISVSSMESRILILHIYTSWGLQVLTEARNLMMMAKSELKKKFKSQWSNLTSARRVNGSSFGLNTYGLYAYDSVRHLAVALDSFFARGGNISFSTDSNLNELRGGKLNLDALKMFNGGSQLLQSILEVNTTGLIGPIKFNPDGNLINPAFEVINVIGTGTRTIGYWSNSSGLSLDPPEKPQRKLQSNGSSIGIQRLYSVIWPGQTTQKPRGWVFPDNGRKLRIGVPNRVSYREFVGIKGTEFTGYCIEVFLAALDELPYAVPFKFVPFGDGKKNPENHELLHMIQIGEFDGVVGDITITTGRTKMVDFTQPYIESGLVVVAPIRKLNSSAWAFLRPFTPMMWGVTGIFFLVVGTVVWILERRTNEDFRGPPRKQFVTIIWFSFSTLFFSQILIINSSYTASLTSILTVEQLSSPIKGIESLATGNDPIGFPKGSFVGKYLTDELNIHSSGLVPLNSPEEFEKALKDGPRAGGVAAVVQERAYMELFLSVRCGYSIVGQEFTKMGWGFAFPKDSPLATDMSTAVLKLSEKGDLQKIRDKWLMRSACSAQGAKQSVDRLPLKSFWGLFVLSGIACFLALLLHVITTTKKQKDDGKSPSCIRFFNGRGIHRHLFPHIPRR
The following text describes a protein:
Function:
May be involved in cytochrome c oxidase biogenesis.
Subcellular Localization:
Mitochondrion.
Sequence:
MHPDLSPHLHTEECNVLINLLKECHKNHSILKFFGHCNDLDREMRKCLKNEYMEKRNKSRELGNAMRKRLFNPPEESEN
The following text describes a protein:
Function:
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MSSTIRASQLVSSSATDEKQPSVFDIIAQENLATSIRPALQHLVKVSCFLLLRLANIEYFQYLAFFKPKTFLSVHKNFDEYYLIFDLILQNHYLKNYGASFTENFYSMKRVVTKNGSMPNDGRERILSLLTLVGWPYVEDKLNQLHDRLKEVYEIRSWSSITDIKSKCQKMFVVIWPYIKTVLKAVKTVLQLAYILNRSSIHSPWLYFSGVVLKHLTPEDLDAFNAVPLHLQTGFFNRIWRFFLGLPGIISRLFAYGLFFVQFLDYMYNTDLAKLTKTGLNSAIPPPPHKMIIKESEVLSLDTNKCPICLKKRVNDTALFVSGYVFCYTCINQYVNTYQK
The following text describes a protein:
Function:
An odorant receptor which affects chemotaxis to the volatile odorant diacetyl. Specifies AWA neuronal cell fate via the odr-7 pathway.
Subcellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein.
Sequence:
MPARVIFQRFLASLGLLNNAILIILIWKKSPKKLGNYKILMIYIAVFEILYSLLDLLTTPECFSKDSVFLIIINLNSTFVPEFVATCATVAYCSLFGMSLAIFAIHFVYRHLVVEKSPLIFQNHVRKILLLILFTILIGCSWTTSTAYLCGSNIYADEYLTRQYLPLKNLNLPDIKYIGSFFRFPDENGGFHYNWNSFIALSFMLILINLSFLTVFYCGYRIYKTINTLSSISSSAESSLNSQLFWALVFQTIIPVILMHIPACAAFSFSIFDYSFELLGEIPTVTILLYPVLDPLPNFCIIKNYRQAILGFFRCFKPRAGSVQPHTRTV
The following text describes a protein:
Function:
Catalyzes the hydrolytic deamination of cytosine to uracil or 5-methylcytosine to thymine. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSTELSEKDLAYLREAIKVSQQARDEGQHPFGCIIVDENDNVIMSAGNRVPDGDVTQHAETRAVGLITKTRRDLEKCTLYTSTEPCAMCSGAIFWSGIRRMIFGLSNENLIKLTQKSGECPPLYINSRDILGAASHPIEVVGPYIEDEAIIPHKGFWDGGR
The following text describes a protein:
Function:
Plays a role in promoting translation.
Miscellaneous:
MISCELLANEOUS: The name 'Mextli' derives from the Aztec god of storms and war.
Subcellular Localization:
Cytoplasm. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Note=In germ line cells, predominantly cytoplasmic. Accumulates in the perinuclear meiotic nuage (also known as germline granule or P granule) during oogenesis but disappears from there around stage 8.
Domain:
Binds to eIF4E1 using a novel tripartite interface in the C-terminal domain comprising a canonical helix which engages the eIF4E1 dorsal surface, a non-canonical helix which engages the eIF4E1 lateral surface and an auxiliary helix that lies anti-parallel to the canonical helix on the eIF4E1 dorsal surface. The tripartite binding mode compromises its ability to compete with eIF4G1 for binding to eIF4E1 but once bound, the complex is very stable and is resistant to competition by eIF4G1.
Sequence:
MAHTHLGRAVKNIEAPRPLKTQSRSSLKNSYLVIEELIQLIDNVTVGLQSCNTTPESITLLLHNLRVHGPQLEAVSKDTLDRAFVVFRNASQDERLNITTRLKLLELIELRAKSWDNDDTIAYYKSKQQISNVELPSEYQYDAGVQPGAFSTSPTFGVSGGVGGVNDGAAAAAAAVFNAASAAAAAQAAAIAAVGTSNQQHMLLPPGEVIRNSGKFPKPTKIPGKTYCKDEVVIRNADSGKVMGIKGRRVHMIEELSETIISFQRVNPGAKERLVQITGPAEDKINYAKQLMEDTIRRNASPVRLEPAPAVGGSCSSLNSSNSDDAIVQPRTPTGSSLANRLSFNSAQNFMTATAAAQQISQQMHHQTHHLQHQQQQQVAAVAAAAAAAAHAQATAAAGKVLRPNQQLLMHSYSTNDASVGEYKFTVNVGQHLIKITGDCCELVRVAKLVLDDYFSSSEFLASIEAGAAFDGTSLVTTPSTPLPGAGPPQFWLPGTDSGIGLNCVVSSSANNNGEGDDEVFAEPSNGGSSTSNQNGLARSRRSHFSRKESTPETKGAREKGDLDDLAGTNSLKSNASRVSYDIEHLLYYSMSPHSWTLPTDWQKMQETAPSILRNKDLQDESQRFDGDKYLASIKTAAKRDIVAADEVETLDE
The following text describes a protein:
Function:
Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MMSMAQQAEPAVTTPPAPGPKQTDGRTRERSVALRVLARPEVGVFLGAVAVFVFFLIAAPTLRDGGSMATVLYQSSTIGIMALPVALLMIGGEFDLSAGVAVVTSALTAGMLSYQLTMNVWMGVVVALVASLAVGAFNGWVLVKTGLPSFLVTLATFLVLQGVNLAVTKLVTGNVATDDISDMDGFDQAKALFASSFDVGGVEVKITVVWWLVFAALATWVLLRTKYGNWIFAVGGSQESARAVGVPVTFTKITLFMLVGFGAWFVGMHQLFSFNTVQSGEGVGQELIYIAAAVIGGCLLTGGYGSAIGPVFGAFMFGMVNQGIVFAGWNPDWFKAFLGVMLLGAVLINLYVRRAATRR
The following text describes a protein:
Function:
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MEAKALPLSHFRARAGSPLLLSAEASSAARKGSGAPGRSRTSRYDAGAPPSRAGRGGVWKRDDPEDSPRRTGMTGVPKLNPKFSTKRAGTSKVPIINFEVSHHRAVAAVRLLRADKGKAFVDLLNEKANDSGENEMGYVERTLGFSTRHLDDRDIRLVTVIVAGTVRWKRYIDYLIMSLCSEEKVFSNMEPLLLQILRIGFFEILKLNVPAYAVVDENVRLAKVALRPGAGNMVNAILRKLLLLKETDSLPLPNIEGDDRAQARALSIIYSHPVWMVRRWIRFLGKEEALKLMNWNNSDPYFSLRVNTTNGYTRDDLVNRLEDLQVHYEKSIMDEFVRIREGMQAVLQAGLLKEGMCAVQDESAGFVVSVVDPQPGETIMDCCAAPGGKTLFMASRLAGQGKVSALDINKGRLRILMEAAKCHNLDDIITDIHGDLRLYAKESTVKYDKVLLDAPCSGLGVLSKRADLRWNRQFEDLEELVCLQDELLDSASLLVKPGGVLIYSTCSIDHEENENRVTTFVQRHPEFTPQGVHGYVPAEFITDDGFYSSSPTKHSLDGAFAARLVRSMH
The following text describes a protein:
Function:
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence. Enhances the DNA binding of OBF transcription factors to OCS elements (By similarity). Involved in the regulation of root development. The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements. Element of a regulatory network controlling indole glucosinolates (IGS) biosynthesis, probably by inducing the expression of accurate genes (e.g. CYP83B1). Promotes apical dominance.
Subcellular Localization:
Nucleus.
Sequence:
MPTNSNHQHHLQHQLNENGSIISGHGLVLSHQLPPLQANPNPNHHHVATSAGLPSRMGGSMAERARQANIPPLAGPLKCPRCDSSNTKFCYYNNYNLTQPRHFCKGCRRYWTQGGALRNVPVGGGCRRNNKKGKNGNLKSSSSSSKQSSSVNAQSPSSGQLRTNHQFPFSPTLYNLTQLGGIGLNLAATNGNNQAHQIGSSLMMSDLGFLHGRNTSTPMTGNIHENNNNNNNENNLMASVGSLSPFALFDPTTGLYAFQNDGNIGNNVGISGSSTSMVDSRVYQTPPVKMEEQPNLANLSRPVSGLTSPGNQTNQYFWPGSDFSGPSNDLL
The following text describes a protein:
Function:
Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A and HDAC1. Required for B cell lymphopoiesis.
Subcellular Localization:
Nucleus.
Sequence:
MVPSRPCESWVPPARPGGDAVDVPPHPSGQQPPHPLGALGWEPRRAPPPCAGDPPGTPSRAAEDEPEDVGLFIPMEEQSGEEGGRRRRRQQRATKRKRDGQGPEGRAPQPDDPRRDATLDRTLEDGAKQHNLTVVNVRNILHVSGVRGGRGEARREAGSPGAAGGARGVGPRSPTVPAASAHQAPQFVDIHLDEDDSSDEEYQPEEEEEDETAEESLLESDVESTASSPRGAKRSRTRQSSEMTETDEEGGAPPEAEKASPPTPVRHISAEVVPMGPPPPPPRPRPSKDSAFMEKLHAVDEELALGPLCPDSFQPLDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPGTADDDDWKAWLGGLMNDDVGNEDEGDDDDDDPEYNFLEDLDEPDTEDFRNDRAVRITKKEVNELMEELFETFQDEMGFPHVEDEGQEEEEEEDGPAESRPDFNTPQALRFEEPLANLLSEQHRTVKELLEQLRMKKSSTKQQQEAERAGPHSQRALQTLVLDAAQRARLQQQMQQHVQLLTQIHLLASSNPGLNAEATTTRMFLRELGTFAQSSLALRRPSSPTFQTTFQPCNLEGSVQLIDDFHALGHGDWSPRKTPKKTADYPSLPRRLAWILATRRVFMYPQLLPVCALKAKNPRDKILFTKAEDNLLALGLKHFEGTEFPKPLISKYLLTGKTAHQLTVRIKNLNMNRAPDNIIKYYKKTRQLPVLLKCCEALRPDQWKAPVEREEEHLPFWLKASLPAIQEELRCLAGDSAGPSGPDADPRAEPDGRYPLLPPKRLALTLKPLANRFSRRAWRQRRCPALKPLLIRPGPGPPPPPPELPPPPPPAAQVPARTPRPIQPAEAAPLAPPPGPPAARGPAPARPCKVPLPALAGRRACAPAGRKAPPWPRPPAAVPPPAPLFLTVPAGTVNVVRLLRPLDAGPGRPVPPALPVATLLVNPAPFPCPLDLPPLLVAPDEGGPGPEAPAGPAVGAGRVAEVEERETGRPGEDAAPEPGPGRGGARGGEAEEEEEEPEEPEEGATEEPEEKAAREEEEEEEEEEEEEEDARAGESSPPPPVPPPPAEPGGPHGPPVGSPGADGPGAGPEKGGGAEEEEEEEEEEEDLDELTQDEDDEGMSSASEESVLSVPELQETMEKLTWLASKRQLVQEGDSEEGDSEPEEEEEEEEEEEEEEEEEEEAGDRPGRLQKEDGAPGDPEEKPPSPCASPTATPAAAPSGVTPAGERSKAAGRGRVSHRPRGRRGRGRASKDASKLLLLFDEDILERDPLREQKDLAFAQAYLTRVREALRPAPGRYEDFLRVIYEFESSPQRRTAVELFGSLQALLRPWPQLLRDFAAFLLPDQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQRIIKVLQGCADCVPQEIAELKTQMWQLLKGHHHLQDEFSVFFDHLRPAPARLEDFEEVHWTEEKGYEFDGFEEVALPEEEEDEEPPKLPPPPRSKRKKLRVQNHDKEPDWAVGPTDGTCPGGEGRRTKRRGHSPTKVGGSGRSPPRGPVGPGPLPEAEDPAAAARRHEEEEEEEEDQEEEGGRPEAAEEGKAAEPRPGVRPQSGSPRSAPVPVTPTPGDRRPPAPPPPPTPGPAGPPRPPRAGAPSRRPPPPAPREPGGDPARGAPAAPRPPGGAPRGPGDGDRPPGGSPAGRAGPAGDEPQPRAAEAATVCAKNIKVSSTGEKVVLWTREADRVILTACQERGARPHTFSAVSQRLGNKTPSEVSQRFRELMQLFHTACAPASDDAAGNADPLSDHGEPPSDEEPDD
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MTFITMFNTADVDEKDDTFETCLKNTMESTEPLSYSPNCPLTLSTSVQSLHDGMAMKLGNMQKMDVPEIPTLKAKEEFEEVKYHESPASGKELKCGLCFETFQYVSEFMFHDQIHRATNRFECQLCGRQFQSTSNLKDHYNVHTGERPYKCELCAKAFTQSSSLLTHKRTHTMENPYKCEVCGRLFRDASNFVKHQRLHSQAQQLGRQAHAASQIISEKPYQCSYCEKSFKRTSDLKDHERVHTGERPYQCRICQKCFTQSSVLTGHMRIHTGERPFHCEICGKTFNNSSNFKKHQRTHSVQDMLANVSRDARYSHYKQPLRSKNGIGHSEDINAISYGKEISVNHPRTLPKINLYEEDCKIVLEKNTSQGNGDVIHDLDGLSSPCAGVTDLTKHTDENIPDAKDTGSKVIFHSDEVIAIDDTDDKEDLGAESETKEVGPKINFENLILPKLARSVGPGYKITTPYWANFIKQSSNHKMDLNPQIIGDDLSKTSLQSQDEDLKEARNEDGSTFDLSKDLQVCQPEKQSSGMEEQQESEVISDISSTSDLGESENLFIERTMECWNQSIDGTMGDQDDDDDNDLLFIEMESKPYICFVCSKRFKRATDLKEHLRVHTGERPFVCQVCGKGFTQSSALSSHQRIHTGEKPFQCEICYKRFNNSSNFSKHKRVHTGERPHNCPVCGKSFQEKRRVKRHLKAVHQIQE