lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Netrins control guidance of CNS commissural axons and peripheral motor axons. Promotes neurite outgrowth from commissural axons but acts as a chemorepellent for trochlear motor axons. These effects are mediated by distinct receptors.
Subcellular Localization:
Secreted. Cytoplasm. Note=Mainly secreted.
Sequence:
MPRRGAEGPLALLLAAAWLAQPLRGGYPGLNMFAVQTAQPDPCYDEHGLPRRCIPDFVNSAFGKEVKVSSTCGKPPSRYCVVTEKGEEQVRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQYPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNKPSRAAITKQNEQEAICTDSHTDVRPLSGGLIAFSTLDGRPTAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKECDCHPVGAAGQTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPAAPPPTAASSTEEPADCDSYCKASKGKLKINMKKYCKKDYAVQIHILKAEKNADWWKFTVNIISVYKQGSNRLRRGDQTLWVHAKDIACKCPKVKPMKKYLLLGSTEDSPDQSGIIADKSSLVIQWRDTWARRLRKFQQREKKGKCRKA
The following text describes a protein:
Function:
Alpha chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The alpha subunit of formate dehydrogenase forms the active site.
Subcellular Localization:
Periplasm.
Sequence:
MKTTRRSFLKLVGVSVVGLSLGQLGFDLEDAQAYAVKLKIEGAKEVGTVCPFCSVCCQVIAYVRNGKLVSTEGDPDFPVNEGALCAKGAALFSMYTNPHRLTKPLYRAPHSDKWVEKDWDWTLNQIARRVKDARDKDMILKNDKGQTVNRLESIFMMGTSHASNEECAVIHQAMRGLGVVHMDHQARVUHSPTVAALAESFGRGAMTNHWIDIKNTDAVLIIGSNAAEHHPVAFKWIMRARDNGAVLMHVDPKFSRTSARCDFHVPLRSGTDIAFLGGMVNHIIAKDLYFKDYVANYTNAAFVVGKDYAFEDGIFSGYDPKTRTYDRSKWEFEKGPDGGPVMDPTLKNERCVFNLMKKHYERYTLKNVSDVTGVSEENLLRVYDAFCATGRPDKAGTILYALGWTQHTVGVQNIRTSTLIQLLLGNIGVAGGGINALRGEPNVQGSTDHALLYHILPGYNAMPVAQWQTLADYNKANTPVTTLKNSANWWSNRPKYVASLLKGWFGDAATPENDFCYEYLPKLEKGEDYSYMYVMDRMYHGKLKGGFIFGVNPMNSFPNTNKMRAALDKLDWLVCSELHNSETTDNWKRPGVDPKACKTEVFLLPSAHRVEKAGTISNSGRWLQWFDKAVEPGQARNFADIFVPLVNKIRALYKAEGGTLPDPVLKLHWTDKFDPEEWTRRINGFFWADTKVGDKEYKRGQLVPAFGQLKDDGSTSSLNWLYTGSYTEEDGNKSKRRDARQTPMQANIGLFPNWSWCWPVNRRILYNRASVDVNGKPWNPKKAVIEWDGAKWVGDVPDGPWPPMADKEKGKLPFIMNKDGFAQFYGTGRMDGPFPEHYEPAETPLDSHPFSKQLSSPVYKFHTSDMDQIAKAADPKYPIVLTTYSLTEHWCGGGETRNVPNLLETEPQLYIEMSPELAEEKGIKNGDGVIVESIRGRAEAIAMVTVRIRPFTVMGKTVHLVGMPFAYGWTTPKCGDSTNRLTVGAYDPNTTIPESKACLVNVRKADKLTEIA
The following text describes a protein:
Function:
Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
Sequence:
MSGKCEECGQSAAKYKCPGCGLRSCGLSCVKAHKARIGCTGKRDPTAFVKISDFDDNRIMSDYNFLEEALRVADVAKRSKYKSFVGGRKPGVLKELIYQARFRKTKFVHMANGMSRRIANTTYFNRKRKCMYWRVEWIFHSTDIRLVDENLDEHVNLGTVLEKHLSPQSHSPTARHQLRDFLQQPVDQLKLLFKKELDDAKESYYELNINESLRQQLSFKTVLEFPEIRVVLPSDIDRFSIVEEEPKPVKPAASPVKSVAEELVEQTGKTFREEEIKDEEQDKEQDDMKMYDFLGDLPGQADLLWKSMEVQPPSLMNDVEDGELSG
The following text describes a protein:
Function:
Structural protein of the cytoskeleton.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Exhibits a filamentous organization.
Sequence:
MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELEREEEALASKRFRAERQDNKENWLHSQQREAEQQAALARLAGRLESMNDVEELTTLLRSAGEYEERKLIRAAIRRVRAQEIKAATLAGRLCSRLPSSGPREDSRRQAAHTLDPGKVPEPEQQEQQTEVLEPTPTPEDTSQDVTTVTLLLRAPPGGRPSSPASPHNSPTSASPEPLLEPAGAQCPAVEAPVSSEPLPHPSEAPSPEPPMSPVPSSSRGRVISKPLPGPTEPSDTLDSIRGFSNTKRADPSETKSCQRSLSVLSPRQPTPNREPTSLAGPSQFRRVGSVRDRVQKFTSDSPVVARLQDGPPRTALASPTPTRLPGPSLISTTPASSSSSNSSSPSPSDTSSHKKQRELAHSLAELQSCPQEEGPGGRGLALRSLENRAGGPKPCSEEPSTPPPVAVGTGEPGGSMKTTFTIEIKDGRGQASTGRVLLPTGNQRAELTLGLRAPPTLLSTSSGGKNTITHISNPGTVTRLGSVTHVTTFSHASPGNRGGCNFKMEPDPAEPPSTTVEAANGAEQARVDKGPEGRSPLSAEELTAIEDEGVLDKMLDQTTNFEERKLIRAALRELRQRKRDQRDKERERRLREARARPGESRSNVATETTTRHSQRAADGSTVGTVTKTERLVHSNDGTQTARTTTVESSFMRRLENGSSSSSTTTTTVQTKSFSSSSSSSSSKKMGSIFDREDQTSSRPGSLAALERRQAEKKKELMKAQSLPKTSASQARKAMIEKLEKEGSAGGPGTPRTAVQRSTSFGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAEMLVDCVPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV
The following text describes a protein:
Function:
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
Sequence:
MNVLPPPEAKAAYVEQMFARIARGYDRVNRVMTFGLDQGWRRKVVEYVAPPVHGRALDVGTGTGDFLIELAAWAREGLVVGVDFTVPMMQAGQPKIADLAQSGRAAFVAGDALQLPFPDNTFDAITTGFVLRNVTDIPAALREMYRVARPGATMACLEVARPRHPLLRWGHRIYFEHVVPWIGALLGGDRRAYTYLPQSARAFPPPDDLAAMMREAGWSHVFYRLYGLGAVAIHVGAKKM
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endoreduplication. Functionally redundant with CDC27B in the control of gametophyte development.
Subcellular Localization:
Nucleus.
Sequence:
MMENLLANCVQKNLNHFMFTNAIFLCELLLAQFPSEVNLQLLARCYLSNSQAYSAYYILKGSKTPQSRYLFAFSCFKLDLLGEAEAALLPCEDYAEEVPGGAAGHYLLGLIYRYSGRKNCSIQQFRMALSFDPLCWEAYGELCSLGAAEEASTVFGNVASQRLQKTCVEQRISFSEGATIDQITDSDKALKDTGLSQTEHIPGENQQDLKIMQQPGDIPPNTDRQLSTNGWDLNTPSPVLLQVMDALPPLLLKNMRRPAVEGSLMSVHGVRVRRRNFFSEELSAEAQEESGRRRSARIAARKKNPMSQSFGKDSHWLHLSPSESNYAPSLSSMIGKCRIQSSKEATTSGQSVSDIGSSVDDEEKSNPSESSPDRFSLISGISEVLSLLKILGDGHRHLHMYKCQEALLAYQKLSQKQYNTHWVLMQVGKAYFELQDYFNADSSFTLAHQKYPYALEGMDTYSTVLYHLKEEMRLGYLAQELISVDRLSPESWCAVGNCYSLRKDHDTALKMFQRAIQLNERFTYAHTLCGHEFAALEEFEDAERCYRKALGIDTRHYNAWYGLGMTYLRQEKFEFAQHQFQLALQINPRSSVIMCYYGIALHESKRNDEALMMMEKAVLTDAKNPLPKYYKAHILTSLGDYHKAQKVLEELKECAPQESSVHASLGKIYNQLKQYDKAVLHFGIALDLSPSPSDAVKIKAYMERLILPDELVTEENL
The following text describes a protein:
Function:
Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MTKLPKFSVALLHPRYWLTWLGIGALWLVVQLPYPVIYKLGCALGHLARRVMKRRAKIAYRNLELCFPEMSAQERHTMVVKNFESVGMGVMETGMAWFWPDRRVNRWMEASGLEHIREVKAQGLGFILVGIHFLTLEFGARMFGMHNPGIGVYRPNDNPLLDWLQTWGRLRSNKSMLDRKDLKGMVKALKSGELIWYAPDHDYGPRASVFVPLFAVDQAATTSGTWMLARMSKACIIPFVPRRKPDGKGYELIILPAEYSPPLESAEATAAWMNKIVEQCIMMAPEQYMWLHRRFKTRPEGVPSRY
The following text describes a protein:
Function:
Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). Required for the ubiquitination and subsequent degradation of the B-type cyclin CLB1 by the APC/C complex during meiosis. Required for meiosis I, late meiotic gene expression and spore wall assembly.
Domain:
The C-box is required for the association with the APC/C complex.
Sequence:
MATPHLYHRYNSKSSNKNINSSGNSTEVDRFIPKSVSRNAYKSIPMLNGFDISYSELCEKSPSPERLSSPEFFNELRNTGHYESISTTNEFSMSSISSSSESQVTRSGSARASRNDYSKLTKEQKDHRKNIAHSLGFQLPDRVFTFETTSAEILEKNKAIKNCFGPGSCAEIRSTFDFSTLSPDVARYYIANSNARSASPQRQIQRPAKRVKSHIPYRVLDAPCLRNDFYSNLISWSRTTNNVLVGLGCSVYIWSEKEGAVSILDHQYLSEKRDLVTCVSFCPYNTYFIVGTKFGRILLYDQKEFFHSSNTNEKEPVFVFQTESFKGICCLEWFKPGEICKFYVGEENGNVSLFEIKSLHFPIKNWSKRQKLEDENLIGLKLHSTYQAQAQQVCGISLNEHANLLAVGGNDNSCSLWDISDLDKPIKKFVLPHKAAVKAIAFCPWSKSLLATGGGSKDRCIKFWHTSTGTLLDEICTSGQVTSLIWSLRHKQIVATFGFGDTKNPVLITLYSYPKLSKLLEVRSPNPLRVLSAVISPSSMAICVATNDETIRFYELWNDKEEIINEIQESGIYGSNIIEYMEGIETTHNKRIR
The following text describes a protein:
Function:
Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits. Also required for maintenance of normal cell surface levels of APP and LRP1. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome.
Sequence:
MHFSIPDTVEVKDRSGSTFLAYNIHINGALHSAVRFSDLYQFNEQLKKEYGNRITARFPPRKILSLTAVQVEERRDQLEKYLQGICQDPDVANSSTFTDFLRNCQKETLQALSETVTLDVYLMNGSKVSLKVLSTDSTDDVLEAAMREIKLSEELFHYFALFLIKREEDGEATIQRKLQEFECPYLSVKNLKGTHRIAVRKNFWDSKLEDRIIEDKIGMNLLYVQAISDIERGWVVGPKEAYSRLEELKETGSKKEYLRLARMMKYYGFIQFKPCFTNYPTDNTRVLISCGDRELNFRLQTEDNKIQEGSFKVTRMRCWRITSSQTTTDEGKKEESLELAFEYLLTRDCLQWITVYSGQAILMSLCLQSIVDEIIRLKQNKSLKAPRHKERTNGNFQRDNKVQGGYAQVPQRQAPPSDDNTKTNEVFEGIGNDDL
The following text describes a protein:
Function:
Involved in the regulation of gamete interactions during the double fertilization and to prevent multiple-pollen tube attraction; mediates the redistribution of the gamete fusogen HAP2/GCS1 to the cell surface after secretion upon sperm arrival.
Subcellular Localization:
Cytoplasmic vesicle. Secreted.
Sequence:
MACYQLPAILLILAVLTAASVAPVAQAQSANAHPAGFSECFSGLWDKTGCWQEVYNFYTTGKNLPGLNCCKASLEVGAQCWLTFWVPGGLSPALISQLKSYCTAFVARSGSGSAPAPGMSV
The following text describes a protein:
Function:
Catalyses the transfer of galactose onto proteins or lipids.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MSLRHQYNKGLVKRRTNYGLRAKWLTLCLILFAIELVIVYFRIHDVILVISLHLNIKLDWIRGLETNCEAVPGHNSLKDSRALLNGGENASPLPFCPEMPPNLLGKQELGNEDEDVSLDDLVKNYTLVEPGGRFKPAQCVPRHKVAIIVPHRNRERHLRQFLKAIHPVMQRQQADYGVFVVHQSGTGTFNKAKLLNIGYTEALKQDDYDCFIFHDVDLLAEDDRNLYRCAEVPRHLSVGIDKWDYQLPYDALFGGVIAMTKDQFAQVNGYSNEYWGWGAEDDDMYVRILHSCLGLERAQYDVARYRMAYHPSDKSNRVNPYRYTLLVGAAERQRHDGLNNLHYSLVEKTQLPLYTNISADVGKPPLNPKTVGFGTGIDIVVSISLLLLMLTMTCCTCVKSRLPHVLLCPRRIP
The following text describes a protein:
Function:
Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
Sequence:
MNRVPSQSEIDELRTAFILMDQDRDGRITALEVQSMLQQLGINLREDIVLNLVRQASQSGSTLMNETEFFQWVKRIQALRPPPEQTSGSSADEEAGLDLVAAFRVFDRDKNGFITKDELRLAMELIDESMTEQGLNDLIKMADVDKDGRINYEEFAKMLL
The following text describes a protein:
Function:
In h- cells under nutritional starvation, P-factor induces alteration of cell morphology toward mating, arrest of the cell cycle at the G1 phase prior to the initiation of DNA synthesis and indirect transcriptional activation of the sxa2 gene which down-regulates the signaling pathway.
Subcellular Localization:
Secreted.
Domain:
The Pro-P-factor precursor carries 4 repetitive units. The second and fourth units generate the major form of the P-factor in the cell. The first and the third units encode slightly different peptides, the fate of which is unclear.
Sequence:
MKITAVIALLFSLAAASPIPVADPGVVSVSKSYADFLRVYQSWNTFANPDRPNLKKREFEAAPAKTYADFLRAYQSWNTFVNPDRPNLKKREFEAAPEKSYADFLRAYHSWNTFVNPDRPNLKKREFEAAPAKTYADFLRAYQSWNTFVNPDRPNLKKRTEEDEENEEEDEEYYRFLQFYIMTVPENSTITDVNITAKFES
The following text describes a protein:
Function:
Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Depending on context, functions as a transcriptional repressor or activator. Required for the normal formation of pre-placodal ectoderm.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTENNNTSTNKQNQLSPLDGGKSLMSSSEEEFSPPQSPDQNSVLLLQGSLTHPGATSYSLSALSASQGSHGLQGHQHQLQDSLLGPLTSSLVDLGS
The following text describes a protein:
Function:
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MTSGDLSSVLNILRSLYKRTRTLEEFADGVVFREGRRAALLQPSDTHSFKSFVRGVFVCSDEELQDVPSCNQTCTFPELLAFILNSLKRKRRRNVLAHGYNFLGVAQEDRDADHFRFQGDLSQSAAYIHSSDLWKKVTARLGTDVTRYLLGSCSVFVLAPPSCVFQICGVPAYDRVSMTTASSGFLLRPPSRKHKSFQVGKKTRSANLTKTGSVGDVEESRKRRRVESEVSTRKRKRESEEEESRERRRGVHHEERRQHEAVLDESTLSGKSGENDAAAVKPPPETSAAPPPLEGGPSWRSGAFPPLPSSQCFIRTLGFLYGGRGMHGFCLNRKRRTAAGPRRLQGQDLVRLVFFEGLPYLNGQERKPKKLPLRYFNMVPVFGRLLQRHRKCRYSSVLHRMCPVVELSRAAQGELSSLIPQHCAPHRVYLFVRECLTAVVPEELWGSDHNRLQFFSRVRGFLKSGKFERISVAELMWKIKVMDCDWLKLRRTAGRFPPSELAYRTRILSQFLTWLLDGFVVGLVRACFYATESVGQKNAIRFYRQEVWSKLQDLAFRRHIAKGEMEELSPAQVASLPKGTVISQLRFIPKTDGMRPITRVIGADSNTRLHHKRIRDLMSMLQARVRSAPALLGSTVWGMTDIHKVLRSLAPAQKDKPQPLYFVKVDVSGAYDSLPHDKLKEVITEALSPVQEEVFTVRHYAKIWADSHEGLKKAFARQVDFSDGSMGSTSMKGFVMSLQKSSKVHHAVLVEQAFGSNLRGKDALQFFTQMLTGSVVQHGKKTYRQCRGIPQGSVVSSLLCCLCYGHMENVLFRDIKNKGWLMRLVDDFLLITPDRNQAQSFLSILLAGVPQYGVVANPQKVVVNFQGSEGGGAFPDIRVLPPHCLFPWCGLLLDTRSLDVCKDYSSYAGLSLRYSLTLGSAHSAGQQMRRKLMSILRIKCHPLFLDLKTNSLESAYKNIHKLVLLQACRFHVCVQSLPFAQTVAKNPTYFQQMIWDMAHYANALIRRSNTGLVLGDGAQKGSVQYEAVELLFCLAFLRVLSKHRPVYKDLLPRLHKWKRRLERLLGDLRLARVRQAANPRALLDFLAMQM
The following text describes a protein:
Function:
Acts as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm.
Subcellular Localization:
Cytoplasm, cytoskeleton. Nucleus.
Sequence:
MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQFG
The following text describes a protein:
Function:
Cohesin cofactor dispensable during the meiotic division but playing an important role in DNA repair by homologous recombination (HR) probably by helping SMC5/SMC6 complex. Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication (By similarity). Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for proximal-distal cell cycle-driven leaf growth in both lamina and petiole.
Subcellular Localization:
Nucleus.
Sequence:
MEKTPTQIVSELCSRLLQLSRPNKDSLVKLLREVANTLSKIDQPSATNKEKGLKLIEAELRPLKKSIIKHALLKNRDNDVSLLVTVCVSELFRILAPHLPFEDEYLRDIFTLFIAEFSELSDTVSPYFSKRAKILETVSRLKFCLLMLDEDCQDLVHEMFNMFFSLVREHHQQSLINQKSMKTQQRKANTQQTQHSLFNNILAIMSDVLEEEANSSFVVVILENLVKEGEDTTSGADKLASSLIERCADRLEPLICSFLTSCFMEKDSIQTNLKDSYHEIIFKISLIAPQMLLAVIPKLTQELLTDQVDVRIKALNLAGRIFAQPKHCLSSYVETYQDLYAEFLRRFSDKSAEVRMAALKCGKQCYFANPSGNKASGVLTAIQERLLDFDDRVRTQALIVACDIMKFNMKYVPLNLISEASERLRDKKISVRKKALQKLTEVYQDYCDKCSEGDMTITDNFEQIPCKILLLCCEKNCEEFRSQNLELVLSDDLFPRLLPVEERMRHWVQCFAIMNHIHLKSLNSILSQKRRLQNELRHCLTLWRKAKVDNIEEAQRKKKSYFVKLSACFPDASEAEDLFEKLDRMRDASIFDVLTLLLEELSSTNAQIIKEKFLKMIGVKHSLFEFLRILSTKCSPSIFSSEHVQCLLNQLCGSTSANTQLKAPSIKLLLVILNMFPSYLRGSEKQFLKLLEENDSAADELIVVLSKAAPYISVNFGDYYPVLEKVCLEGTRSQTKCAVSAISSLAGSSEKSVFSELCEMLMDSLLCGRNIPTTLQSLACVGQYSVLEYDNIYEDITSYIYRVFQAEPSDNQLPCDQSSGCCNSCKLKIYGLKTLVKSFLPRHGQVVRKIDDLLNILKKTLKSQGHDGIKSCEDTGANVRLAAAKAVLLLSRKWDLHISPEVFRLTILMAKDSNAFITKTFLTKLYKLLTEHMIPSRYACAFSFSLSSPCRDLHDDSFRYINGFINKATRESRTCRDLDQGESLTDSPVYMTVFLIHVLAHDPEFPSEDCRDEHIYARFCGPLFSVLQVLLSINNNGFTIKETAPFLFCIFRAIKRAEDAVDSRKTPRLHILADIGYSAVNILNSIVVTSPQAPRSILLPSSLYSLTSITDNQNKAKSRTRNALEQSFIERIVHIFQSQISMHDQRCQKDSLAVGSEDKVLPPLLGNQIETSITGSTEASQNNTRCSRKRTHLGEHISCNSLSLRTVESEIPIKKLERHTTCAKESVKASVSNKITSSKHSGVVSALKDISNHGEAIIGQRIKLLSPTDGCFYPGTVEKFNSKSNSHKIIFDNGDVELVCLDSESWETLSHESMGQQERLGKETESYGSRNCVPEISHTLAKVTAQKQTTTTKQQNKKVPAKLNPPAVPCFMMSAKSKKGNSDSGEGSVSEVTDTSDNIGPRRSRRQRIS
The following text describes a protein:
Function:
Binds single-stranded telomeric sequences of the type (TG[1-3])n in vitro. Has a role in meiosis.
Subcellular Localization:
Cytoplasm. Nucleus. Chromosome, telomere.
Sequence:
MMSAEETVTQNAPNTVQDQVEASVDAAVHASAEQSNTPAQQADDFRVFVGRLSTSTKKSEIRSLFETVGTVRKVTIPFRRVRRGTRLVPSGIAFVTFNNQEDVDKAIETLNGKTLDDREIVVQKARPVQEQPIKDRKKSKNKNGEEPETSTSVENAESAKGSSDENEANTATAPSSNEANGVDKKQNEIKGKGGSGKNKAKPLPPNSIYVSGLSVTLTNEGLKEMFDAYNPTRARIAVRSLPPYIIRRIKLRGEQRRGRGFGFVSFANAEDQSRAIEEMNGKQVGDLTLVVKSAVFREDKQNDENEKNENEPIEASESAPTNVSDSTEPKASEVDSEEKSGVTASAITA
The following text describes a protein:
Function:
Zinc phosphodiesterase, which displays tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Can use bis-(p-nitophenyl) phosphate (bpNPP) as substrate. Involved in the processing of small nucleolar RNAs (snoRNAs).
Subcellular Localization:
Cytoplasm.
Domain:
The C-terminus (270-280) is essential for tRNA binding and processing activity.
Sequence:
MEKKKAMQIEGYPIEGLSIGGHETCIIFPSLRIAFDIGRCPHRAISQDFLFISHSHMDHIGGLPMYVATRGLYKMKPPTIIVPASIKETVESLFEVHRKLDSSELKHNLVGLDIGEEFIIRKDLKVKAFKTFHVIQSQGYVVYSTKYKLKKEYIGLSGNEIKNLKVSGVEITDSIITPEVAFTGDTTSDFVVDETNADALKAKVLVMESTFLDDSVSVEHARDYGHIHISEIVNHAEKFENKAILLIHFSARYTVKEIEDAVSALPPPLEGRVFALTQGF
The following text describes a protein:
Function:
Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MLPLLAALLAAACPLPPARGGAVDAPGLLGAPLNASVNASSSDEPAAPRLLASAAPGAPERPEEEAAAPCNISVQRQMLSSLLVRWGRPRGFQCDLLLFSTNAHGRAFFAAAFHRVGPPLLIEHLGLAAGGAQQDLRLCVGCGWVRGRRPGRLRPTGATAGAPTALPAYPAAEPPGPLWLQGEPLHFCCLDFSLEELQGEPGWRLNRKPIESTLVACFMTLVIVVWSVAALIWPVPIIAGFLPNGMEQRRTTASAAAAAPAAVPAGTTAAAAAAAAAAAAAAAVTSGTATK
The following text describes a protein:
Function:
Required for proper anchoring of astral microtubules at the spindle pole bodies (SPBs), during anaphase, ensuring correct cell polarity.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Localizes at the microtubule organizing center (MTOC).
Sequence:
MLHEIILLLAGNTSGLFIEKNGQILLHPSVQPLHPGERELINDIVSLASKRKRIERYIEIFDEDLIQQNQFLLKALRLLLSKKLFLYDESLANLERMIISSDPYFVGSGKFVSLAQLEAHLADWKETLSSLLVLQGNISQCLSVASTFQKLHNMYMGSTHLNFKKLVLECECAFQKTWLDELVQYLVNDSGDDSFKCSFLCGDTKDFVSCSNNVPFLTQDIVNCLVSIRTCMLNAKKCFTDAFCEILRCFYRLVYEMPLPLTKSSVTKLADEMFTLVSEKIIFQLASFHQIFDLVKMLEMVMLLENVEFLPTLSEMFRDVRGEYCSSNDVQGVVIDDILPVVLRKTISLLDLATEYGECVSFLKLVSIFDEEDEMIRSENRKIDVEGLNMQLLLCLKWPFNLFMDKNALNVYSDLWILLGSLHLSITKIKSLFYERKEYTAKGISQPWTQLWVTLWFLSSLQYYAYECVIKPSYCKLRESLTELYRTQKLRMQDCSQLHALTLTYAKKMLFFYDDDLHISLNSIYHELSLFRSQEVSKVDCQLAAHVSHSIECIRQKENDPSYDREIINALIVQLNL
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MLGKKGVPASYATYYSMHIFFCNLSLMIILFSELVNLIGINASPATSDAPRNKGSLGSIIGAAVVAGTMLGLHTNASRSMVVGVIVTIFGICMYGSPLSIMLKVIKTKRAEYLPKMLSIACFLNGICWSIYALLRFDPYILTGSGVGALLAFVQPLLIVIYRNSPPKESLHFPLVVAIFSSPFSASFAPGFAALELRVFQKQPLYHPEGVLRPDVWQFHVMFGEVGKDSKVNIPDDDDHECLLNVQGNPDNCDDDRDSQGPGSNPKNEGSVDPWNPGPL
The following text describes a protein:
Function:
Structural component of the gap junctions and the hemichannels.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAIAHLATEYVFSDFLLKEPSEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPTSFSWRQAAFVDSYCWAAVQQRHPLNSDSGNLPLCLHKFFPYILLLLAILLYLPTLFWRFTAAPHLCSDMKFIMEELDKVYNRAIKAVKSVRGVDVRDGAGPFVASMNENIGQSLWEISESHFKYPIVEQYLKTKKKSKNLIVKYLICRAVTFMIILLSCVYLGYYFSLSSLSDEFVCSIKSGILKNDSTVPEQFQCKLIAVGIFQLLSFINLVVYTLLVPVVVYTFFVPFRQKTDVLKVYEILPTFDILHFKSEEYNDLSLYYLFLEENISELKSYKCLKVLENIKRNSQGIDPMLLLSNLGMIKTDVVDGKTTKPAEKMGTEPGNDATELKVLTDEDISDDAKIDNEEKKIRQRLLESSQ
The following text describes a protein:
Function:
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPHQLQVARTAAVCATAELQGDISVGEHCAVHPGACIRAAGGPIVLGERCFVEDGAVLASDGPDGLHVGSGNLFESGSDVRSARVGDGNWFEPKAQARAGSVIGSNCLIGSGVVVAAGEPLVGAEEVEASDDPVLWFPVLFDAIVNRSVVLEHLPETHDLRVRSIAEEEVAEEVMEVEVEVEASTAQDAVLPPSLQPTDRLVRVDGHDISVLSFQDVIDSPVGSVAVLPLFKPVDSVHVLSGFARVEILSPKMLEFEPATPEREEVVVEWVEEKARLKAEQEAREREIANNKELQERLEQERRVAEALAKKESDLLEKLDKEEYERTRMTPHNLASGKRRDGWEFRYEVEFTTKGPIGLNWDLNTRDKAVVSHLEPKLPANELNVIAPRDQLIALNGVDTSKMGPQEVVEVYLSSAIPRKLVFLVQMSAERAAAKAAEKPINRPVMNWTLTFDAPEMLRGWEVRLHLATWSYRGACTLIDKANHAHAANGKALLIVNNVKGDVHCVPCRMGKLDGELIMSVMEHQEALIRIYRERPDQIPVPVEQPAKLTNQELTIAKDVKKAGRKLTFWYINESMTVADSNEETGSSPSVSMSFEFQVLPALFGGKIPTMPFRIVAAYPQEMACNYKGLGILATRSVVVVKRGGCSFGAKLR
The following text describes a protein:
Function:
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MASSLALKRLVSSNILPNSLRVAIAPSTSRLFNTNAATPDDHDDRRRADGFFSDLQGRRQGAKKDVFDPLSPTRSLNMMDQVKGNRFLSTSRDIPGLGSEAKESNLRPLSPHLPIYKPQLSATLSITNRISGVFLTTALLFSYLLSLKMGSVCFTYSNFYQFFFYSAKLAPVTVSIAALAVSYHLCYGVRHLLADFSGKLR
The following text describes a protein:
Function:
Probable histone demethylase that reduces the levels of histone H3 'Lys-4' methylation in chromatin.
Sequence:
MDGKEKKSGSKRGSKVFQFDDDADDDEPIGSLLEIMKHKSSKKDKVETESTGKQRQKQVVEKKLSALGKDSEDMDDTLASFRKRLKGNKKGVESGTSRVRNHEGVDTVTNSNLKPIEEANKNEVQSVLLRENGASNSIQKCASETGTLLHKFSGKDKAASPSHEKVETVSSEKEADVFHQITKEESEIPMSEKAVELSRVSVPMPDVHGEVNCTIAPDKHIHLGEPTSESGYYREKNLVMCDCGTQFNFEDRSFESNTQVTLCQKCKYSSHHNASNGGGIQVNTLEDGTAQASPVSIIPCEDENFRGDAISLPNSGKPSTLQRPERIAKKRKLGNMVYEGDVKWENEQGFLDCQSDKSFKGSDKCGFVPSISKEIEIGRAAAVTAGLKAQSVSPIEKIILKEVLKRKGSNQEYLVCRNSILGLWSKNVSRILPVTECGVTGGPSESELPSASLIREVYKFLDQRGYINAGISSVNGKAASSTNQDYDLLQGRQLEESSMASVADSEEGVAFILGQVKAVESTSEGKKCALQNDERDLVGCATSEMLESISKKCEASIIDDNKRSVSMNALQDSTASNVEKHPETFSVAKPALSSTLSSAHSNQMRGRDCVPCEVIDEKKVIVIGAGPAGLTAARHLQRQGFSVTVLEARSRVGGRVFTDRSSLSVPVDLGASIITGIEADVPSERMPDPSVLVCNQLGLELSVLHGFCPLYDTVTGKKVPAELDDALQAEFNSLIDDVDLLVEEIGKERANKMSLEDGLEYGLQRLRMPHDKVNIDKFGLLNSSSKTGIRGPFMQDESWKDDFLNPLERRVMNWHFAHTEYGCAAVLKEVSLPHWNQDEFYGGFGGPHAMIKGGYSRVVESLAEGLDIHLNKIVSDVSYVSDVSAMDNSKHKVRVSTSNGCEYLGDAVLVTVPLGCLKAETIKFSPPLPDWKYASIKQLGFGVLNKVVLEFPTVFWDDSVDYFGATAEETDLRGECFMFWNVKKTVGAPVLIALVVGKAAFEYTNKSKSEHVNHAMMVLRKLFGGDLVPDPVASVVTDWGTDPYSYGAYSYVAIGASGEDYDVLGRPVQNCLFFAGEATCKEHPDTVGGAMMTGVREAVRIIDILRSGNDYTAEIETLEKAQRKSVPVRDEVRDLIKRLEVVELSNVLARQSLLRNMFFSAKTTVGRLHLAKELLNLPGETLKSFAGTKEGLAVLNSWILDSMGKNGTQLLRHCVHILVRVTSDLFALRLSGIGKTVKEKVCAHTSRDIRAIASQLVNVWLDLYRKEKANSGKKSLRQANTTNTSRIRRKLNSPDTDSKGKLSNGNDVKTDEEFEDNQLPMSEEEKAVFAEAEAARAAAEAAAKAFSEAYHNTSLQLPKIPSFHKFARREQYAKMDESDFRKKFPGNVLGRQDCMSEIDSRNCKVRDWYDFPASCLDLDSARIPVDNYSQPSHSNELVSHSKFRECSGESVAADTSFLTGAWVDTGGSSDGFKDSQAIDRWQSQAAAADPEFFNRTLHIKDEEDSIACSTGPPSWKHDQRANECSVSQVTVNKEPHKNHIRSADRLKQGVVDFVASLLMAPYRAKKIDRDVYKSIMKKTATKVMQHTTDVEKAMAVTQFLDSKRKNKIRDFVDKQVDKYMVIPQVPKP
The following text describes a protein:
Function:
Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MPITKRKRTQVLTKTKKKTPEKKELLVKKLKQSLKKYQRAIIFQYKNLSTNPLKEIQQAWKSDSKLFIGKNKVMQVGLGKGEEQSATKNSYLLSPFLKGETGLLLTNKTLQEIQEYCDTYKIPEFARAGHISDQTIVLKEGIDTLKGFAHSIEPYLRKLGLNTQLINQQIVLNEKFILAQEGKPLTVEQTKILRLMNQKLAYLEIAPLCVLEKNGTFKKL
The following text describes a protein:
Function:
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
Subcellular Localization:
Nucleus.
Sequence:
MASNSPDIHDIEVLGTFSIDEKGNYQNDSSQRRFLVETVNDHLQFDLRDGIDDYIAQNQRKVRYASLSSVQDWIHDNMQELTERKILETERGGTRKLNVDFVGSTEVFSLLLRACECIDRLEILVRRCNGTYYIESSPRKYQRSSATTPARYELSEMKYAGRKFATSITSTDEGGVPTADEPVNANATYVVVMKRQLGDHSFILSTDVQAERIDSIQTPPGNYVCIRSRKAHLVGNTNFKK