lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Sequence:
MKQRPISAFFGAGKAKDADKGATQAKISAFFGNKTPGAAAAKPEGGATPAPAPVPAPGDKPTPPPAAANASGAAPTRGDTPAAAPAAAPTPAPAPAPAAAAAAATAAPAKTPAGGSTSKPAKGGAKGAAKAKAGKDVGNSTSKAAKGKKAAGGSKAAAASRKRLRRVVMDEEAGDDGAAAGLEDNLEDESDTDKGDDSDYEAEGSGSDEESSADEEQDSDGGSDGDDDGAEDESECDDNAGVGKKRKRGSNAKAAAPAAKRTPAPAKSKPAAAAAAATPAAARTPAAVSAGMNAATPAHGTASKGPASATAGGRTATATPGTVALGSAGRSGGLGGGRSAAATPNTGGGAHTPSSSVRSLRSGMSDCATDVSVPEVTLGVAASMDGDAARFAERMASRFPFLHPDRIRDAAKRRPDDPEYDPRTLHIPDTWFKDAKVSEAQQQWWNLKAANFDSVLLFKVGKFYEMFEMDAYVGVDVLGLAFMKGEQPHAGFPEVKYADMAEGLARAGYRVVVVEQTETPEMLAKRNEERKKRGMKTCNVVDRQKVAVLSRGTLVDAAMVASRPDAAYVLAVYEMEEPAPAAAAAAAASADGSSVSPAGAGVRIGLCAVDCASGQVLLGEFVDDDVRSCLRTQLTALQPQELVLPAVPLSSVTQTVLRNGLRNPQRNLLKGKRGEWSADKTYRMLRDRDYFTASAAHPEPGSGSGGSGAYGTEDDPWAGASGGGAGDAMDVDGGAAAAAGAGGGAAAVGAAAAGAGGTGQPPELDPSKRWPALLRRFVAEGVAARPAAMAALGGAIVFLTEALLDRAVLPLGRFEELPALVPSAAASGAAAGADGEGAADADAEGGLPAYMGLNGAALENLEILENAEGGSAGTLLSVLDHCTTPFGRRRLRQWLCRPLCRCGDIRLRQDAVAALMEGALAEAAGQARKLLAGVSDLERAITRLHASTVEGGSGRDAANVVLYEDAAKRKVAALTGALKDLRSAHTALGKLRDALARAGGGEGGGSMLLRRIVVDREWDEVGAWVPAESLTLSPVDSLFVRMGARDSIMTGQSTFFIELAETAAMLARATPDSLVVLDELGRGTATLDGAAVAGAVLAHLAGAVGCRGLFATHYHHLSDEHAQDSRVAVMHMACAVEGAEEPEAAPAGKGAEAQGGDEVTFLYRLSPGACPKSYGTNVARLAGLPPSVVARAAQVSATWDRERGSQAGGGAGGELGRLLASVAACVGGGPQAEGAMQVDVEVEVDVEKLQQLQAAAAALVASA
The following text describes a protein:
Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Sequence:
MASESSSSSGAVVTDRRGIPAAQFVEDVRTYLSQLQLDVQSALAFLQERLQQYKLVEMKLLAQQRDLQAKIPDIKKCLDIVATLQAKKEAATGEPLVADFEISEGIYSRARIEETDSVCLWLGANVMLDYSYEEAITLLQKNLDNAKASLEVLVADLQFLRDQVTITQVTIARVYNWDVHQRRVQLAGASVEDS
The following text describes a protein:
Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MPQLDTSTWFITILSMLMTLFILFQLKLSKHIYYPTPEPKFSKTHKQNTPWETKWKKIYLPLLLPQQ
The following text describes a protein:
Function:
Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth. Probably the protease that cleaves RIM101.
Miscellaneous:
MISCELLANEOUS: Present with 432 molecules/cell in log phase SD medium.
Sequence:
MNDWHEFNAAIKSIYCNAEGDSSSIINRLVGLAMKSEDSTFIEAVLVLKENVSKVDKQLRFLWLTSTINSRFYPPIPISEASPVSWNKTEYCAPGTEELQRRYPGRAKLQNEEDYSGGIEQCRDVPDCSLVASLINLRSKNLNLPLIKQISSTKYHVNLSFNGSNKRLVTVDISQIPTSVDGKQLSLKSNDISDKIGELALLLVSKGTYSTDGSNISIDTYRLSGFLPEITQVNSYPFEKLWKFHKSNLCLMGAGTGNRSNDMIKPLVENHDYSIIDITYDSRLVKLRDPRNSALNVEISYEQYLKNFKQLYLNWNQEKLFKRSQVLHFRYDTSRYNKFSIVADKPLFHLVNNSKVTETVWLLLESHLQDEGSQENRSVSFLNEAPECIICPIEPPVECGGNHIGLQLVKLRLDAETERLLYCYSTTNNNFSIHSFSVVKEICFQRLKDTKSLFAKVLFSFPYEIEGKASFDTCNFFQNPTFELEVHSEQDYQVLMDAACISTSSHDLINIQVYYFNDYELIKPIMFDNHYQPGQGLKQDVPILTNVKYMIVCSTYGPPASTEFELLASIRLSSSWRLISGITLRSVNLIYGTYPYHCRNRFHWKETSDKLKIQMTLPTKKYSTNKLFIRVVPVESSARLRMRCNIFEPESALCVYECQEYRTCPSGGIVIPDLEVSRTNIVVLMIERSVPISSCLPTEGQLDELELFVGSSQKIRIEKYSDDVIPK
The following text describes a protein:
Function:
Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export.
Miscellaneous:
MISCELLANEOUS: Present with 2840 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MKIEKASHISQPVQLSTCTLIDTYPGHQGSMNNKEVELYGGAITTVVPPGFIDASTLREVPDTQEVYVNSRRDEEEFEDGLATNESIIVDLLETVDKSDLKEAWQFHVEDLTELNGTTKWEALQEDTVQQGTKFTGLVMEVANKWGKPDLAQTVVIGVALIRLTQFDTDVVISINVPLTKEEASQASNKELPARCHAVYQLLQEMVRKFHVVDTSLFA
The following text describes a protein:
Function:
Scaffold protein required to form the phloem filament matrix in sieve elements.
Sequence:
MAQRFQLNSQTLPTADPLKRVSLIPRSAEQRLADNAGERRPLAPRSHEDNPFGGHTDDHHVAAPADHNKVMDHNSENLGSIVPKTAHYPHPSEEILDANIRHSMVPKSLGPNSLGGRFGPGKKQAFHRNGRPMFSLSDDRVMADRVLKTHSPDMIFFDVTSLLSVVNDIFKSHVPSIDSSAPKPSLVFKDYADHTSFETFADLIDQISCEIDCKCLHGGESHGMMTSGLHLDSRNTTTFSVLSLVSKYRWDAKLVLVLSALAVKYGVFLLLAETHATNQLTKSLALIKQLPSIFSRQNALHQRLDKTRILMQDMVDLTTTIIDIYQLPPNHITAAFTDHIPTAVYWIVRCVLICVSHISGASGFKQDQIMSFMEVSEIHENSERLRKINAYLLEQFKKSKMTIEEGIIEEEYQELIQTFTTIIHVDVVPPLLRLLRPIDFLYHGAGVSKRRVGINVLTQKHVLLLISDLENIEKELYILESLYTEAWQQSFEILWVPVQDFWTEADDAKFEALHMNMRWYVLGEPRKLRRAAIRFVREWWGFKNRPILVALDPKGQVMSTNAFPMVWIWQPFAHPFTTARERDLWSEQEWNLEFLIDGTDPHSLNQLVDGKYICLYGGEDMQWIKNFTSLWRNVAKAANIQLEMVYVGKRNPKNGIQPIINTIREENLSHTLPDLFQIWFFWTRVESMWESKQRMLKAHGIKGREGFKEEEKDLVLQEVVAMLGYGGEGDGWGLVSKASDMMVRAKGNLFSRGLAEFNEWEVNIPTKGFLTALNDHLLMRLPPHHCTRFMLPETAGIIPNEVECTECRRTMEKYYLYQCCLE
The following text describes a protein:
Function:
Probably catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA.
Miscellaneous:
MISCELLANEOUS: The zinc-binding residues of the alcohol dehydrogenase family are not conserved.
Subcellular Localization:
Cytoplasm.
Sequence:
MQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAGQEVLLTGWGVGENHWGGLAEQARVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVLPRDEFAESRPLEKQVWAGAIDTVGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRAQAWQRLVADLPESFYTQAAKEISLSEAPNFAEAIINNQIQGRTLVKVN
The following text describes a protein:
Function:
Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Subcellular Localization:
Cytoplasm, myofibril, sarcomere, Z line. Note=Localized at the Z-line of skeletal muscle.
Sequence:
MIPKEQKGPVMAAMGDLTEPVPTLDLGKKLSVPQDLMMEELSLRNNRGSLLFQKRQRRVQKFTFELAASQRAMLAGSARRKVTGTAESGTVANANGPEGPNYRSELHIFPASPGASLGGPEGAHPAAAPAGCVPSPSALAPGYAEPLKGVPPEKFNHTAISKGYRCPWQEFVSYRDYQSDGRSHTPSPNDYRNFNKTPVPFGGPLVGGTFPRPGTPFIPEPLSGLELLRLRPSFNRVAQGWVRNLPESEEL
The following text describes a protein:
Function:
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
METTRQNKISRLLQKELSEIFLLQTKAMPGILISVSAVRISPDMSIARVYLSVFPSEKAEEMVKNINENMKSIRFELGTRVRHQLRIIPELKFFVDDSLDYIEKIDSLLK
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MKAPPKPTSGEQQGAAAAARKVMNSELWHACAGPMVSLPPVGSLVVYFPQGHSEQVAASMHKKDTQNIPSYPNLPSKLICMLHNVTLHADSETDEVYAQMTLQPVTKYDQEALLISDMGLKQNKQPGEFFCKTLTASDTSTHGGFSVPRRAAEKIFPPLDFSMQPPAQELVARDLHDQSWTFRHIYRGQPKRHLLTTGWSVFVSSKRLFAGDAVLFVRDEKSQLLLGVRRANRQQSALSSSVISSDSMHIGILAAAAHAAANNSPFTIYYNPRASPAEFVVPLAKYNKAMYSQVSLGMRFRMMFETEESGVRRYMGTVTGISDLDPVRWKNSQWRSLQVGWDESAAGERPSRVSIWEIEPVVTPFYMCPPPFFRQKFHQQTDIDTEIENAYKRGLTMPMPWLENMGMKDGSSSIFPGLSLAQWMSMQQNHHGFQTSNIQPVSSNSISFEDPSKLLSFQSPPNPNSNKPNQRNQLVTPLQQLSPPWPQHQQQQQLHHQQQNYVYNQLHQQQKPQSQQNSGSTQTQQQISGLANRSTLQPLSISQHQIEQQQQQQTQLQQSQSHLLQQISGSTQTQQQISGLANRTLLQPLSISQQQQQQQQQQQQTQLQQSASNLLQQQQTLQMLQNLQQQQQQLFSPVEPLQQQVLQQLKQQQQQQQLSGNSLSTSSLMQTNQQQSQYKPLRVHHPSGDGDVPSCSTSPSTNNCQLTASNFRIKNQQGLSALGDYSMLDHPSKFLHELQSQSTCDIRVKHELSNLKLPDQSKDKAVATEPTTSVTSYCLDAGVGSLPHNYNIPNLCLEGDVVAHSQTRSDLSFGAHIDGLPPDALLSRGFDSHNMMPNYVNGGSRDIETELSVAEISPQSFGMPDMPFKPNENISPAAKDTSVVGNGLWGNDQTQQQQQQQQQQQRMRTYTKVQKRGSVGRTIDVTRYKGYEELRHDLARMFGIEGELEDAQWKLVYVDHENDILLVGDDPWEEFVSCVQSIKILSYSEVQKMRLEGDLGVASSGTDSGNMWRGAYDDNSAAASFNR
The following text describes a protein:
Function:
Involved in the activation cascade of caspases responsible for apoptosis execution. Effector of steroid-mediated apoptosis during insect metamorphosis. Overexpression promotes programmed cell death. Interaction with Diap1 is required to suppress Dronc-mediated cell death; via Diap1-mediated ubiquitination of Dronc. Rate-limiting caspase in rpr, grim and hid death pathway. Recruited to the Dark apoptosome, an adapter protein complex that mediates activation of the caspase cascade in programmed cell death initiated by the intrinsic apoptosis pathway. Association with the Dark apoptosome stimulates autocatalytic cleavage and activation of Dronc, promoting Dronc-mediated cleavage of downstream effector caspases such as Drice.
Miscellaneous:
MISCELLANEOUS: The promiscuous caspase inhibitor p35 is neither cleaved by Dronc in vitro nor blocks Dronc activity in vivo.
Subcellular Localization:
Cytoplasm.
Sequence:
MQPPELEIGMPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHRRLLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDSRPPFISLNERRTSRKSADIVDTPSPEASEGPCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYKMQSRFNRGVLLMVNIMDYPDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLGFNKKLYFNPGFFNE
The following text describes a protein:
Function:
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.
Sequence:
MQRVNQLVKVRHLVNSRIGFLSTPREFSALPNYAQNDDLQDQVLVEGRAKSRAAILNRPSSLNSLTEPMLARLKRLYESWEENPDIGFVLMKGSGRAFCSGADVVSLSELVNEGRVDECKSFFQILYKFAYLQGTYLKPHVAILDGITMGCGAGISLPGMFSIVTDKTVFAHPEAQMGFHPDAGASYYLSRLPGYLGEYLALTGDKLNGAEMIACGLATHYTLNARLALIEERLGRLVTDDRTVIETSLAQYGDLVYPDKTSVLHKIETIDKCFSHDTVEEIIDALENEAASSYDAWLKAALTKIKEASPLSLKVVLQSIREGRFQSLDKCLAREYRISLTGVSKRVSNDFCEGVRARLVDKDFAPKWDPPSLREVSEDMVDCHFSPLSELESELELPTAIRESYM
The following text describes a protein:
Function:
Plays a role in determining ER morphology.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.
Sequence:
MGVFNALVSGSFLPWKRSNRETDYETVLSRLEGEINTVQSRLTQIRLRERRASVTLTLQAFVLWAMYTSVCWFLGLFSLPRTHGWDAEVGWKNARMLSVWLPVLGSPVLILSTRRIVRWWYRRIGAAEDKHLIDLKRQKREKIDEIKRATKYDHLRTLLERYDEAGAKPTIVNARASASASAASTPIKGTNRSMSSSPSSKEDSSANATPQRAPTTPEAQALQAQRMAFMRQQANAVQPPRRSPPAAMVPMQKTWLDKLADAILGADPTVTGPEQKYALICARCHAHNGLALKQEFSEVQYICPHCAHFNSRRPSSAPVGSPFNSNNPGGARGTPRASHQAVHALVDTTPSKPSSTERGSRLKLRADDSDDDDDDDDDEDRPPIATLQESREPISINSEAPDAKEQSTMPLRSRKSHTNTSENSMDMDDD
The following text describes a protein:
Function:
Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.
Subcellular Localization:
Mitochondrion.
Sequence:
MKLPKILYDAAAFGGPRSTGFVKILNLNGRSSYKSSYLVNQNLMDEALVKSNLLKEYNSEKMTILEMAPGPGVTTTSLFNYFQPKSHVVLESREVFSKPLQKLCTLSDGRIKWVHQDGYYWQTYEDVYVSKVLDPRIQTEEEQKLSPHRELLFFAHLPHGYAGLLFVSQILDFLSARDWLGIFGRVRVLLWLPCSPTVTLLGSRGFSKRSKTSVFREAFTDSRVLAASESTLQKLCMGYSKEAKENYQISPNPLLVSPTPITSEPHKEDLTLVEMCSKPQDKQLSIPVFESIVRILLTCKATSLSKSIYYLGPGAETLLPSFTQCGINIDMPVGLLSAADFLTISKIIQKYPFKHHLHLGTIIEDS
The following text describes a protein:
Function:
Primary efflux pump for manganese. May prevent manganese intoxication.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MASEREQISRKVALIALIANLILMAGKVFFGLVGDSEAVFADGIHSAADVVASIAVLAVIGISNKPPDQDHPFGHGKAEVISEAIVGIILVIVSVYILIEAILSFVKGPSVPQYSALFAALISYVAKEILYRYSIKQGKKWNSKAIIAIAYDHKGDIVASLAAFIGVLLAIIGNSRGWSYLLYADAIASAIVAYLIFKISMELIRPSVDVLMEKSVDPELIEEYKAVIFQCDQVKRIDRIRAREHGHYKLLDVRLSLDHDLTIKQGHDIAREIRNEIKRQFSDVEEVLIHVNPYFEE
The following text describes a protein:
Function:
May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.
Subcellular Localization:
[Isoform 1]: Cell membrane. Postsynaptic density. Note=Isoform 1 was found in synaptic plasma membrane and postsynaptic density; [Isoform 2]: Cytoplasm. Membrane; Peripheral membrane protein. Synapse. Note=Isoform 2 was found at excitatory synapses and also at non-synaptic membranes and within intracellular compartments; [Isoform 3]: Cell membrane. Postsynaptic density. Cell projection, dendritic spine. Endoplasmic reticulum. Cytoplasm, cytoskeleton. Note=Isoform 3 was found in synaptic plasma membrane and postsynaptic density. Isoform 3 was also found in dendrites where it was associated with microtubules, endoplasmic reticulum and dendritic spines; [Isoform 4]: Membrane; Peripheral membrane protein. Note=Isoform 4 was exclusively membrane associated.
Domain:
PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4.
Sequence:
MLAVSLKWRLGVVRRRPKDDGPYSKGGKDTAGTDGALVCRRQSIPEEFRGITMVELIKREGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNVGDYIRSVNGIRLTRLRHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIISKTVDVSLYKEGNSFGFVLRGGAHEDLHKSRPLVLTYVRPGGPADREGSLKVGDRLLSIDGIPLHGASHATAIATLQQCSHEALFQVEYDVATPDTVANASGPLVVEIAKTPGSALGISLTTGSHRNKPAITIDRIKPASVVDRSGALHAGDHILAIDGTSTEHCSLVEATKLLASVTEKVRLEILPAPQSRRPLKPPEAVRIQRSEQLHHWDPCVPSCHSPRPSHCRAPTWAPGGQDQSRSVSSTPFSSPTMNPAFPCANASTLPRGPMSPRTTAGRRRQRRKEHRSSLSLASSTVGPGGQIVHTETTEVVLCGDPLSGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLAINGIATEDGTMEEANQLLRDAALARKVVLEIEFDVAESVIPSSGTFHVKLPKRRGVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDHCPMEYAVQILRQCEDLVKLKIRKDEDNSDEQESSGAVSYTVELKRYGGPLGITISGTEEPFDPIIISGLTKRGLAERTGAIHVGDRILAINSVSLKGRPLSEAIHLLQVAGETVTLKIKKQLDRPLLPRQSGSLSEASDVDEDPPEALKGGLLTTHFSPAVPSVDSAVESWGSSATEGGFGGSGSYTPQVAVRSVTPQEWRSSRLKSSPPPLEPRRTSYTPGPTDESFPEEEEGDWEPPMSPAPGPAREEGFWRVLGEALEDLESCGQSELLRELEASIMTGTVQSVAVDGRPGSRPWRRSREVGTSPEDLQELLLPTPLEMHRVTLHKDPVRNDFGFSVSDGLLEKGVYVHTVRIDGPAQHGGLQPFDRLLQVNHVRTRDFDCCLAVPLLAEAGDILELVVSRNPLAQSRRTPGAPGPSSPQMI
The following text describes a protein:
Function:
Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSDQIRASGYFYSQTDDPFAAAFWSQFQDPHVLAARHIPADSSASAAMKAYREYRDRVRKPVLATYTILGFLSSGTYGRVYKARLRTPPQLASSSGTAGIANANAGTGSGTATVGSGASTAKKRGGLLQQHQLLDSPSSSLHATPKSVADGAGVGVNGTPSASPSLSASLGTSTANAPGGSDNTLQLSSNELPDTQIYAIKKFKPDSKETDATIYTGISQSAMREISLNRELSHVNIVTLHQVMLEDKAIYMVFEYAEHDLLQIIHYHSTALRAPIPLAVLKSLLWQLINGVAYLHANWILHRDLKPANILVTSQGVVKIGDLGLARLYSSPLQSLYNGDKVVVTIWYRAPELLLGARHYTTAIDMWSVGCIWGELLALRPMFKGEEAKMDPKTKAAPFQTDQLKRIVEVLGTPNKDRWPAIESMPDYKGWWPHLRLDNYPKTLSRWYATRNKGDDGYELFNSLLQYDPEQRLTANQALEHAWFTAQDPKPTANAFSSLAKPHATYPNRRVIQDDMDPKMKSNYVPPIKSHHMQPWHQVNLNSSQPHRLAQLMYQQEQMRHQQMQTQAPAPAPAQPPAATAVTGRLGHAVGAGSSAVGTAANVGGPAAPPPIAIGSTAGTGGAIGIQSSAASTAPSQHMYNNNPLITIAGTNGGTISNPATVRSSHSIGSTESITPTTSSQPIPAQPSSAPLARTTNLVATATRNQQRKRQRN
The following text describes a protein:
Function:
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MGPSPLQIKVNALKRLIKEEKLSKQEVAEQEQHINQMKANNADEYELKKQIQVLEESQRMVPEVTKKVAEYRQALKEFLDSYKGDEDVTEAKELL
The following text describes a protein:
Function:
Part of a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy.
Subcellular Localization:
Cytoplasm.
Sequence:
MISFEDFLLRPSKVVDPFNRFVAKIDPFLTLVEFCQVIGPKPLAVVSQRPDDKIRGVDINDMAIWLMSSDTVPGTMIVLENNQTGVYAAAYYFNLYDMRARAFQRNLCIAYLCSEKPTKETLNLFSSAMKKLVSPVLICNRRLFIRHVTDIVKFSDSVDETTLKQYYTLNGDSQKLSDGSRFNVVFEQTRLLKSKFLTKRFQEMAFDDDICCGHNAENMNEAEDIICSFRVPSIPLSPVETLTPCAYSSIIPKLRQLCSELCSSGSPNRNSTHGALFCGHRPIATTSPAATTTLPWNTDSGKSDNDKNGEETLKEVTGHLGDVIFPLLCGEDLVVCGAEQRKSTVEDMLGKLSRVVPRESARNVEENIKIEKDPNRIGNGLGGLLCNRNETGKLARWRNVLDMNRSALKTFTYDGSLLAGLNKKRKFPSDRSLVLFIIAYLTNICQLAFICRYMFIKSPNSIEKALGDQQKLSSDDERILINLLMGIDFEKFNQLKVSSKDGAKPSRTINL
The following text describes a protein:
Function:
Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes; Regulates also the sphingolipid metabolism.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MKCVECCAPVSYLYTKFGRGNQNIRLAQCDNCKKFADKYIELDFVLLSIDVILMKPQVYRHLLFNSLNSRNFRNVLNFAFLVILFDVFLIWSRLETRATQFPLSVTKESFVSRPIALQYLFLLFLCISETIVYHLALLLLLRLCLGWRLFQSACGAVIMSSSTKMLPVFMVIWDYDVPAAAMVVEWVVLLSNTEALSILLENVSFFRIGLLVFFASLCRSVFVYGLLHVLTFLPLQPPAHCMSLGPHLSFLCKLVHSVTLTTQTAV
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MLYKSLKASTIIGRKCFHWWNNLPITWKVGIACSVLFPPLWNYNERRKAKEKQIFYNKSIRDYVFFDIAIENKYVGRVLIGLYSDQVPLSTENFIQLAEGYQIKDKYIGYRNTSIHKIYPGIGLVGGNVLNDKEGLSIYGKKFPDENFDMEFVQDGDVALFNEGPHSNSSQFIITFSPMPILHKHNVVIGTVLKGMNIIRMIENVGTKLGHPMYNVRIVNCGLYKGLEKDGPPFFNFTEIIEKNKEHLISKKEFEKLSKEQRQSLLNDSNKTEKKKKQAL
The following text describes a protein:
Function:
Required for DNA mismatch repair (MMR), correcting base-base mismatches and insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of the MutLalpha heterodimer that forms a ternary complex with the MutS heterodimers, which initially recognize the DNA mismatches. This complex is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in maintaining the genetic stability of simple sequence repeats and in the repair of heteroduplex sites present in meiotic recombination intermediates. Does not seem to be required for homologous somatic recombination.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice site and an intron retention.
Subcellular Localization:
Nucleus.
Sequence:
MQGDSSPSPTTTSSPLIRPINRNVIHRICSGQVILDLSSAVKELVENSLDAGATSIEINLRDYGEDYFQVIDNGCGISPTNFKVLALKHHTSKLEDFTDLLNLTTYGFRGEALSSLCALGNLTVETRTKNEPVATLLTFDHSGLLTAEKKTARQIGTTVTVRKLFSNLPVRSKEFKRNIRKEYGKLVSLLNAYALIAKGVRFVCSNTTGKNPKSVVLNTQGRGSLKDNIITVFGISTFTSLQPVSICVSEDCRVEGFLSKPGQGTGRNLADRQYFFINGRPVDMPKVSKLVNELYKDTSSRKYPVTILDFIVPGGACDLNVTPDKRKVFFSDETSVIGSLREGLNEIYSSSNASYIVNRFEENSEQPDKAGVSSFQKKSNLLSEGIVLDVSSKTRLGEAIEKENPSLREVEIDNSSPMEKFKFEIKACGTKKGEGSLSVHDVTHLDKTPSKGLPQLNVTEKVTDASKDLSSRSSFAQSTLNTFVTMGKRKHENISTILSETPVLRNQTSSYRVEKSKFEVRALASRCLVEGDQLDDMVISKEDMTPSERDSELGNRISPGTQADNVERHEREHEKPIRFEEPTSDNTLTKGDVERVSEDNPRCSQPLRSVATVLDSPAQSTGPKMFSTLEFSFQNLRTRRLERLSRLQSTGYVSKCMNTPQPKKCFAAATLELSQPDDEERKARALAAATSELERLFRKEDFRRMQVLGQFNLGFIIAKLERDLFIVDQHAADEKFNFEHLARSTVLNQQPLLQPLNLELSPEEEVTVLMHMDIIRENGFLLEENPSAPPGKHFRLRAIPYSKNITFGVEDLKDLISTLGDNHGECSVASSYKTSKTDSICPSRVRAMLASRACRSSVMIGDPLRKNEMQKIVEHLADLESPWNCPHGRPTMRHLVDLTTLLTLPDDDNVNDDDDDDATISLA
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MFVSFRALDLNLLKVFEALMTEGSVTRAASALTMTQPAVSNALARLRDALGDPLFVRSGTGIRPTQRAVVLWEPIGEALESVRGALDEQVFDPARAQTEFSLSMSDYVSSLVMPDLLGHLGKVAPKARVHTVPNTILEIADQLEDNRVDCVMSVYVNEAQQPAAIRSRSLWTVDYACFMRRGHPLAGMKRLSTRTFLNAGHVDVSLAGKTMPSYDLFLASRGLSRNLVATVNHYSAAYEVVRQSDLIAVLPSDLRSQSRHAPLLHAMPLPLQAPPRIVSLFWHQRNDTVPAQRWLRETLVEMFARSD
The following text describes a protein:
Function:
Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MYGKIIFVLLLSEIVSISALSTTEVAMHTSTSSSVTKSYISSQTNGETGQLVHRFTVPAPVVIILIILCVMAGIIGTILLISYSIRRLIKA
The following text describes a protein:
Function:
Regulates membrane-cell wall junctions and localized cell wall deposition. Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Sequence:
MEHGEISSKAPLVAPVAAGVNRAVAVVDTFLRFIAIIGTIGSAIAMGTTNETLPFFTQFIQFEAKYSDLPSFTFFVAANAVVCTYLVLSIPLSIVHILRPRARYSRLFLVFFDTAMLALLTAGASAAAAIVYLAHKGNVRANWFSICQQFDSFCERISGSLIGSFAAMVLLVVLITLSAFALARRH
The following text describes a protein:
Function:
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
Sequence:
MNLRKDKVVQSTDGDALSSKYSAVQKGYLQDEFIDLFVAGSKQAAAQQGPGSARKVVAQFQPKLPLINRGTFVRHHAIDVLVDRFLAAKKPGQRVQIISLGAGSDTRPFSLWSSKPENRDEILYHEIDFAVSVERKRDIIMQDSTLRELVGAQEYDKTTGMHTQRYHLHGIDLRSIGPGFVLPGSDPSLATLIISECCLCYLEPDQAKQVIFWITSEFTNSTIVMYEPLSGQDQFGQVMIENLASRGISIPSMTKFPSLESQIERFKAAGYTEVLATSMDVIHDEWLSPEEQQRIHGLEFLDEREELLLLLKHYCVVWASNLTK
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in sperm flagellar axoneme, which is required for motile flagellum beating. Forms an extensive interaction network cross-linking the lumen of axonemal doublet microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MPVLIPPVEHSQDTRVGHPAWREATRALAEEAHQLTDRCGQEAVTMWQPNESVRDPHVAHHLCRAAYILPWRFRVEMLKGGSTMEKPPPGEGVTLWKSKMKPPAWHARLPLPMHRDARALQTAEVVQAHARGARLTAARLGRAQHQINGQLRLLQRQREATDRRLSEVRKALLINQQSVKLRGYRPKSETISDKADSMLTWEKEELKSMKRKMEADMEKSEALLKTLASCRDALVFCCKERLQAVELMNQPLDKVLEQAGRHSWVNISRVPTPRTQGLKTPPPDPVGTYTPECAKALYEAKRLLMESKDTLLDMAKNEEDIREQQQQISDRVCASLAQKMRETLELKDRLNMTLGLMRGTIHRCTKFNQEMYITRGLIKGPLSKSHLETREKLDRPLVRMYQRHVGTQLPEAARLAQGTDKLQRHISHVEKNLDELLSMRKKLTWSFNCKKIGHNVDYSVVRLRLRQRHPQVCYEQAQRLVNDWDPRTPPRVKSNTAITK