lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
Sequence:
MAQLSDDCFAFGGPMMSVDEAVGLITTRVNAIADLETVALVDADGRVLARDIAAPLPLPPFTNSAVDGYAVRDADLPDSAERAFPLDGRIQAGGLVQAPIRPGHTARIFTGAPMPPDAGTVFMQEDVRIDDAARIVLPPGLKPGANVRPAGEDIPQGHVALRAGQRLRPQHVALAAAFGLTRIDVVRRIRVAVFSTGDELASPGEPRAASQLFDSNRFMLMAMLRRLGCEVSDLGILRDERTSLANGLKQVAGSHDLILTTGGVSTGEEDHVKAAVESIGSLVLWRMAIKPGRPVAMGIIGGTPLIGLPGNPVASFVTFVHVVRPTVLALMGGLPEPLLPIPVRAAFTYKKKIGRREYIRVSLRRGQDGALEAIKFPREGAGLLSSLVETDGLVELGEDITRVEPGQSVGFLSYADLL
The following text describes a protein:
Function:
Hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth. May also act on acetamide, propanamide and butanamide (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAPRTIVKVDLNKPAWEQPNLHNRWHPDIPFAESIDEGETVKIECLDWTGGQIKNDDSAEDIKNVDLTRIHYLSGPFEIKGAEPGDVLVVEIQDVQPLENQPWGYSGIFAKENGGGFLDEHYPKAAKAVFDFEGIFCSSRHIPGVRFPGLIHPGIIGTAPSKEILAEWNRREGALVAENPHSTHVMAQLPNASYAFAGILADEKLSATVASEGARTIPGRPENGGNCDIKNLSRGSKVFLPVHVPGAKLSIGDLHFSQGDGEISFCGAIEMAGSITIKCKILKNGISDLAMKSPMYLPGPVEPHFSPSRYLTFEGFSVDESGKQHYLCTTTAYRQTCLRVIEYFRRFGYNDYQLYLLLSCAPIQGHVAGIVDIPNSCTTIGVPMDIFEFDVSPNGKAKIIDLGSCAFANS
The following text describes a protein:
Function:
Zinc metalloprotease that cleaves 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Domain:
The JAMM motif is essential for the protease activity.
Sequence:
MVTLSSPSPSLSCVENVTCKSSHVSRVLISGTDNINHGESSEAKILRDVHISERLLEDFTELARENTEKDLETCGTLAAFLERGIFYVTTLIIPKQESTSNSCQAMNEVEVFSIQNERELYPVGWIHTHPSQGCFMSSVDLHTHYSYQVMVPEAFAIVVAPTDSSKSYGIFKLTDPGGMEVLRGCSETGFHPHKEPEDGNPVYEHCSNVYKNSNLRFEIFDLR
The following text describes a protein:
Function:
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLYYLFEWLHKLNFPGAGMFGYTSFRALMAVILALLISSIWGDKFINLLKKKQITETQRDAKTDPFGVNKVGVPSMGGVIIIVAILIPCLLLGKLDNIYMILMLITTVWLGSLGFADDYIKIFKKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPDVVIRENIEVHTPGQEMEVIHGTNDLKSTQTTIPFFKSNNLDYADLVGFMGEHAQTAGWFLFVIITIFVVTAVSNGANLNDGMDGMAAGNSAIIGATLGILAYVSSHIEFASYLNIMYIPGSEELVIYICAFIGALIGFLWYNAYPAQVFMGDTGSLTIGGIIAVFAIIIHKELLIPILCGVFLVENLSVILQRFYYKIGKRKGVKQRLFKRTPIHDHFRTSMSLVEPGCTVKFTKPDQLFHESKITVRFWIVTIVLAAITIITLKIR
The following text describes a protein:
Function:
Involved in early development of embryos, especially in the process of gastrulation. May play an important role in establishing and specifying rhombomeric segments. Seems to be required to maintain the cells in a highly undifferentiated state. In contrast to POU2, T-POU2 lacks DNA-binding activity because of its incomplete pou domain structure. Overexpression of POU2 does not have any effect on development, whereas overexpression of t-POU2 causes developmental retardation or arrest before gastrulation.
Subcellular Localization:
Nucleus.
Sequence:
MTERAQSPTAADCRPYEVNRAMYPQAAGLDGLGGASLQFAHGMLQDPSLIFNKAHFNGITPATAQTFFPFSGDFKTNDLQGGDFTQPKHWYPFAAPEFTGQVAGATAATQPANISPPIGETREQIKMPSEVKTEKDVEEYGNEENKPPSQYHLTAGTSSIPTGVNYYTPWNPNFWPGLSQITAQANISQAPPTPSASSPSLSPSPPGNGFGSPGFFSGGTAQNIPSAQAQSAPRSSGSSSGGCSNSEEEETLTTEDLEQFAKELKHKRITLGFTQADVGLALGNLYGKMFSQTTICRFEALQLSFKNMCKLKPLLQRWLNEAENSENPQDMYKIERVFVDTRKRKRRTSLEGTVRSALESYFVKCPKPNTLEITHISDDLGLERDVVRVWFCNRRQKGKRLALPFDDECVEAQYYEQSPPPPPHMGGTVLPGQGYPGPAHPGGAPALYMPSLHRPDVFKNGFHPGLVGHLNS
The following text describes a protein:
Function:
Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MFPAIESLAMTFPTLLADTNADFWFPIQGSSFAEEVDWVYDLILYISLAFFVPMMAFMVWCLFKYIKARGTKAESQISHHTTLELTWSIGPSVLLVWMFVQGSISFLDMRTPPEGSYDIGVQAFKWGWTMDYGNGTFHPELHIVKDEPTKLSMRSTDVIHSLFVPAFRAKKDIVPGRYNYMWFKPTVASEQISDEALAKIKKQSEGTTWDYDKVHTIQTEDGERELQVTPEGYTFFDLYCTEYCGKNHSEMQTVVVVHETQAELEAWIKANSSRGPIPMEEWGELLYGRRGCSGCHSVDGTKLVGPSFKDLYGSQHALTTGENQVVDENYVRESIIAPKAKVVAGYQPVMPSYQGQLSDDDIASIIAYLKSISANAPSQPAGAEAESEEESAE
The following text describes a protein:
Function:
Plays a role in neuronal and neurobehavioral development. Required for normal expression of neuronal markers elavl3 and eno2 and neurobehaviors related to circadian rhythm and changes in light-dark conditions.
Sequence:
MAASGGQKSEKLDEAQALARSCAGRPDFLPCDGLSICATHSHGKCFKLHWCCHLGWCHCKYVYQPMTSVCQLPSTAVPVAPSGHTHTMNLSISLAERFLRTAPKFQAPPCPESPKFCVISDLFVDDYMVKRINGKMCYVQRPPPPTPNPTHQPQTAAPQPVPQRSKNSHQVGPTVKQGQAKEKISAPKMDHCSSPSSSEDSGINALGLHYMESCDEDSCVDDDDEEEEDDELSTDGNSSPGSFWDQDECTLLSPSKSIVEIIEKIETTV
The following text describes a protein:
Function:
Component of the clr6 histone deacetylase complex I responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Subcellular Localization:
Nucleus.
Sequence:
MDVLSRVFDNEKEELDPLLNNPLTASEFRAKKAELEAELESIRNGTCKTLLDLADELRRSRDEELEIAERWRTFLVNRAQEEYEVEMKAAKEEYEYRCKTLKEMVLSHLNEKKRKIYEAKDMFDIGSESSTLLLHDASSQFIDRRKLRHRRNAGNQQNTQQLPSLNFFDDYLLFPTDETAVIPQSVKNAVRNSVNSVKPTSAEASLFSPLLSMANANPTNGRERDPRASERAERDREKAVEKGLSGATEEDIQSDLQLLKKELAKKK
The following text describes a protein:
Function:
Protease that acts as a positive regulator of the cGAS-STING pathway by catalyzing desumoylation of CGAS. Desumoylation of CGAS promotes DNA-binding activity of CGAS, subsequent oligomerization and activation. Deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.
Subcellular Localization:
Cytoplasm.
Sequence:
MEGRPSPSSHVSFRIPKKKPNNKSEDVQVQSPLARLPGSQHWDYPLREWRLSASNRETSTKGRRQRDCDRCSSNDEESIGQPKVILTNVLRTKIGRKYTQAQPKTDANFSDAGKLQSNQPPSSSVASLKIWQILNPALHSPFLSKRQPQVILTNVLRTRIGRKYVDSHILIDSNLSDAEKLQLGQLASSSVASAQTCQILSSPHESSFLSERSEHCLTKSDVNLSKESERGNVVLTFRRRKLEKKENKSSDELDKKRKNMNSTSSSWKGSSSLDSEKRKRRFSGHISDDCKERIPEKSLLRSKEQRLSSTRSSGCRTPCEDEQDHRSDLVQDSVAQTLERDCKDTPTNNQLRPAHSCSEEAGSDSAPSDLSEKQLIAVSPQVSTIRKVKTDTSQYLNKLRNRNCRSNRPLVSADPIVLSSDDEDRSSEPKEEEGLSEPKCMEQLQDNITDVQEIEQQSDVRFSEKLMEDNVESHTEQLLTKSDDDKCPTNLPSGNIHSEQMKPGLDFEFDSIYIGIFKWSSTGPVRFMTKYITIPFQVALNKNIKLTVDTLDVRRFGLWRNDGGCSSTTVIFIWLSVDYLEKIETQLGKRVSSEPSKCSEFIFLELSQPLPEQDVVRLSELITEISKKNRAPDLLELLSLKQALLLFKDLSPEESSFISSREDLLKQCATKESISFAQEPTFQKPKPKVARPSYALANKQNSGCYSISLSSAPNEEWKEVGESGAVKNLIVYPPPPAKGGLGVTREDLKCLEYGEFLNDVIIDFYLKYLLLEKAPKHLAERTHIFSSFFYKCLTRTEKFSEEDPKVSVAQRRHKRVRTWTRHINIFSKDYIFVPVNEESHWYMAVICFPWLEETVYEEHPHQNSLNLSPLQSENKSEDSVIGSVLAYPEEEMDANRILFSKGGNESAASASGLDSGISKISLNNSKRQVCKRPCILILDSLKAGSVQKTVQVLREYLEVEWEVKRKTRREFSKSTMIDFYPRVPKQDNSSDCGVYLLQYVESFFQNPIVDFEQPVHLEKWFPRQVIRSKREEIQDLILQLHFQQLRGSRS
The following text describes a protein:
Function:
Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MDWQALWLSVKLSSITVLVLVPLSILAGRALAYRQFIGKSWVEALIMVPLVLPPTVIGYYLLVGLGSQSWLGQWLERLTGQQLVFHFSGLVLASVLVNIPFALQPIQRAFEAVPHDVRDAAACCGMSKLKILLKIELPMVWPGVLTAIVLCFSHVLGEFGVVLMMGGNIAGETKTISISIYDSVQAFDFGAAGTMSLVLLLFAITALALTTSLSRRLGGQRGANHR
The following text describes a protein:
Function:
May regulate actin polymerization.
Sequence:
MSVQADDPLEPFYFEHEEQEICGKLVAPITDSFQEDYPSVVDRFFTRYYYFKGDVPYQVLYHSNRICLICLAPEHPALAQGISSVNFDIGNVDRSQNVVKGKGKKGGMILQAESTLALLTTANGGTYKVPSCIRGKLVEVNTAIVEEPKLLEQLPEGAGYFAILLPKIENCDAIKASLLTQEQYEERLKSKNEGLPQIESTGDHAQNKNKEIQA
The following text describes a protein:
Function:
Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.
Subcellular Localization:
Cytoplasm.
Sequence:
MTVSQLLKQRVRYAPYLSKVRRAEELLPLFKHGQYIGWSGFTGVGAPKVIPTALADHVEKNGLQGQLAFNLFVGASAGPEENRWADLDMILRRAPHQVGKPIARAINDGRIKFFDKHLSMFPQDLTYGYYTRERTDGKILDYAIVEATAIKEDGSIVLGPSVGGSPEFMSAADKLIVEVNTATPSFEGLHDIDMPVLPPHRVPYPYTRVDERSGLDAVPVDPARVVALVESTERDKVGPNTPSDEGSRAIAGHLVEFFENEVRHGRLPANLLPLQSGIGNIANAVIEGLAGASFRNLTVWTEVLQDSFLDLFENGSLEFATATSIRLTEAGFEKFFANWDEYSSKLCLRSQVVSNSPEMIRRLGVIAMNTPVEVDIYAHANSTNVSGSRMLNGLGGSADFLRNAKLSIMHAPSARPSKTDPTGISTIVPMASHVDQTEHDLDVLVTDQGLADLRGLCPRERAREIIRQCAHPDYKPILTDYLDRAEHYAQRSRSMHEPHILQQALRFHTHLAEKGTMKVPSWD
The following text describes a protein:
Function:
Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.
Subcellular Localization:
Nucleus.
Sequence:
MAKDKPVSVKDAVFKLQMSLLEGIQNEDQLFAAGSLMSRSDYEDIVTERSITNMCGYPLCSNALPSDRPRKGRYRISLKEHKVYDLQETYMFCSSNCLVSSKTFAGSLQAERCSGLDLEKLNNVLSLFENLNLEPVETLQKNGDLGLSDLKIQEKTERSSGEVSLEQWAGPSNAIEGYVPKPRNRDSKGLRKNVKKGSKTGHGKSISDINLINSEMGFVSTIIMQDEYSVSKVPPGQMDATANHQIKPTATVKQPEKVDAEVVRKDDDSIQDLSSSFKSSLILSTSEKEEEVTKSCEAVLKFSPGCAIQKKDVHSISISERQCDVEQNDSARKSVQVKGKTSRVIANDDASTSNLDPANVEEKFQVEKAGGSLKTKPRSSLKSAGEKKFSRTVTWADEKINSTGSKDLCEFKEFGDIKKESDSVGNNIDVANDEDILRRASAEACAIALSSASEAVASGDSDVSDAVSEAGITILPPPHDAAEEGTVEDADILQNDSVTLKWPRKTGISEADFFESDDSWFDAPPEGFSLTLSPFATMWNTLFSWTTSSSLAYIYGRDESFHEEYLSVNGREYPCKVVLADGRSSEIKQTLASCLARALPALVAVLRLPIPVSIMEQGMACLLETMSFVDALPAFRTKQWQVVALLFIDALSVCRLPALISYMTDRRASFHRVLSGSQIRMEEYEVLKDLVVPLGRAPHISSQSGA
The following text describes a protein:
Function:
Calcium-independent and membrane-bound phospholipase, that catalyzes the esterolytic cleavage of fatty acids from glycerophospholipids to yield free fatty acids and lysophospholipids, hence regulating membrane physical properties and the release of lipid second messengers and growth factors. Hydrolyzes phosphatidylethanolamine, phosphatidylcholine and probably phosphatidylinositol with a possible preference for the former. Has also a broad substrate specificity in terms of fatty acid moieties, hydrolyzing saturated and mono-unsaturated fatty acids at nearly equal rates from either the sn-1 or sn-2 position in diacyl phosphatidylcholine. However, has a weak activity toward polyunsaturated fatty acids at the sn-2 position, and thereby favors the production of 2-arachidonoyl lysophosphatidylcholine, a key branch point metabolite in eicosanoid signaling. On the other hand, can produce arachidonic acid from the sn-1 position of diacyl phospholipid and from the sn-2 position of arachidonate-containing plasmalogen substrates. Therefore, plays an important role in the mobilization of arachidonic acid in response to cellular stimuli and the generation of lipid second messengers. Can also hydrolyze lysophosphatidylcholine. In the mitochondrial compartment, catalyzes the hydrolysis and release of oxidized aliphatic chains from cardiolipin and integrates mitochondrial bioenergetics and signaling. It is essential for maintaining efficient bioenergetic mitochondrial function through tailoring mitochondrial membrane lipid metabolism and composition.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.
Sequence:
MSINLTLDIYIYFLNNARSFCGKQRSKQLNFLCSKQYWRMNHVNVHREFHTSKKSCKWNRSEAHCSKHWHSSSNHGVHIGIVKLSTSAPKGLTKVSIHMSRIKSTLNSVSKAIFGSQNEMVSRLAQFKPSSRIFRKVSDRGWLKHKNVKQAIESLKNYSDKSAEKNSFAEQKSYFADKEEGSDKHSLYHYAYRITTRFGESFYFLANHINSYFKNKEKMSQIKEDRQLQDKPCLEESKSISPSPDILTDRPDSGPPLNVEDKLSSSTQLPEALPVSTKQSIANFLSRPTEGVQALVGGYIGGLVPKLKSDPKSQPEEEEEPSKTDEPICKDKKAEEKKRVLLQREKIIARVSIDNRTRALVQALRRTTDPKLCITRVEELTFHLLEFPEGKGVAVKEKIIPYLLRLRQIKDETLQAAVREILALIGYVDPVKGRGIRILAIDGGGTRGVVALQTLRKLVELTQKPIHQLFDYICGVSTGAILAFMLGLFHMPLDECEELYRKLGSDVFTQNVIVGTVKMSWSHAFYDSHTWEKILKDKVGSALMIETARDPLCPKVAAVSTIVNRGQTPKAFVFRNYGHFPGTNSHYLGGCQYKMWQAIRASSAAPGYFAEYALGNDLHQDGGLLLNNPSALALHECKCIWPDTPLECIVSLGTGRYESDVRNTTTYTSLKTKLSNVISSATDTEEVHIMLDGLLPADTYFRFNPVICENIPLDESRNEKLDQLQLEGMKYLERNDEKMKKLAKILSREKTTLQKISDWIKLKSDMYEGLPFFSKL
The following text describes a protein:
Function:
Pore-forming subunit of the mechanotransducer (MET) non-selective cation channel complex. The MET complex is composed of symmetric dimeric MET channels, each channel comprising two copies of pore-forming ion-conducting transmembrane TMC subunits and auxiliary proteins including the transmembrane inner ear protein/tmie, the calcium-binding protein/calm-1 and arrestin domain protein arrd-6. Sodium ions are the most permeable, whereas calcium and potassium have lower indices. Sodium-sensor ion channel that acts specifically in salt taste chemosensation. Required for salt-evoked neuronal activity and behavioral avoidance of high concentrations of NaCl.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Domain:
Contains ten transmembrane domains with putative domains TM4-TM8 that line the channel pore; Interacts with tmie through transmembrane domains TM6 and TM8 and via a tmie palmitoylated residue; Interacts with calm-1 through cytosolic helical features including the helices H1 to H3, and H5-H6.
Sequence:
MQEAARRASLRKEHTPTNEKFGDLSKQDSLGERASSKLTLDDELYDILYAFGETDAFINKGDKQRETDEDGNPLTRQALLERIRQKKEVIGKLRCQAWSMTRKRRTLKLAQKYLEQHESKVSRSHLYMEEMRKRARLMKRSFSNFKTYLIPWESKIKRIESHFGSVVSSYFTFLRWIVFVNIMITLIALVFVVLPETLADSVANEGRFNRTKTRKQIPANERVHADELAVVWHYDGYLRYSPLFYGYYSDDPFLGNKIKYALPLAYFMVTLTIFAYSFFAILRKMAANARMSKLSGSKAEQYIFNWKLFTGWDYTIGNSETASNTVMAVVIKLRESIADIKKDAHGKFRLLQFSLRVFANIIICAMLGFSIYCIIFAVQKSQVQDDGNLFTKNQVPSVVSTITHVFPMIFDLIGKMENYHPRTALRAHLGRVLILYTVNYITLIFALFEKMTALRDRVNSTSTSSSHRTKRQQGGWNPNMQRPPPYASRAEVRQMSDFLAANTRRFQTVSQRTTRSVTTPFTVAPQFGPFNVNNPNAVFHNGTHSTSFESQILGPKALPIFTPPPRKYPGFTPGNVGQQFGGPDFPRNQVYTKSTPLPRVRTKPPWVYTTTHPPLVQNRAMTTTMSKSAKKGNSKNLDDDILLSNETIQMSEAALRRNHDGHNNDICWETIIGQEIVKLVTMDLIFTILSILVIDLFRGLWIKYCSSWWCWDIETTFPEYGEFKVAENVLHIINNQGMIWLGLFFAPLLPAINNIKLIILMYIRGWAVMTCNVPAREIFRASRSSNFYLGILLIWLLLCTLPVGFVIASMSPSRSCGPFARYQHFYTVVTREIEKRVDQTVLSYIRHIASPGVVIPIILFLILIIYFLFSLVRGLREANTDLQAQLVHERTEEKKKIFELAGGKKNKFEKDRDKKRSNDYIPLIEQRRREPWRQYHEMEADHALASDSSEESDINEDEDDERQPLTAYPLRAIETPPETLQVTAFHPSLGSLIENREMEDEESASGDQLPMIHKSVSFQGPSHMQMRQSISTESCSQISRSAIQVATPEEIRALLRPYLEAKYGIPYQHGIKSFPIDVHTPPNNTPSRRSSKYNSFVSLYEHTRDDHKNFVASTIKETDEDPGKSDKKQTSSKDVAPDFMPWPSADEARALREKMKSKTPLMLTKTTVEEKPKGGKSSESEFRPPVPIHRKYNIQTTEEENEEEETDSAPESSKKRFRISVSPTKTIAPASASRAQHKIVSQASSSSSIPHGRQPDPNKKASLVLPPLRAPRVQFDEDDSPRQID
The following text describes a protein:
Function:
Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development.
Subcellular Localization:
Nucleus.
Sequence:
MSESSDIPTGTYSLSLGRSFDTKGRKNDPKAAQFHTLRYDFKPSSVSNNVDNTFIAFGSNSQDVHVSVPSEGGDNMTVYKGSKKDAKPKECLLFFDKKTGMVRLEKITSNINVKKTRDLDPATEQALKRGIERLRTTASSNPQHLSSSSSPEEKQRPPPPVQDTSDSESDSDSDSDDKSNVDSSDDDERALMEQMKQQQPAEQPTNSYHQESHVAPPPPSYNTSYGSSSSNRNTRINKDSEKYGLALSESSDEDD
The following text describes a protein:
Function:
Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics.
Sequence:
MIPVILSGGSGSRLWPLSRKQYPKQFLALTGDDTLFQQTIKRLAFDGMQAPLLVCNKEHRFIVQEQLEAQNLASQAILLEPFGRNTAPAVAIAAMKLVAEGRDELLLILPADHVIEDQRAFQQALALATNAAEKGEMVLFGIPASRPETGYGYIRASADAQLPEGVSRVQSFVEKPDEARAREFVAAGGYYWNSGMFLFRASRYLEELKKHDADIYDTCLLALERSQHDGDLVNIDAATFECCPDNSIDYAVMEKTSRACVVPLSAGWNDVGSWSSIWDVHAKDANGNVTKGDVLVHDSHNCLVHGNGKLVSVIGLEDIVVVETKDAMMIAHKDRVQDVKHVVKDLDAQGRSETQNHCEVYRPWGSYDSVDMGGRFQVKHITVKPGARLSLQMHHHRAEHWIVVSGTAQVTCDDKTFLLTENQSTYIPIASVHRLANPGKIPLEIIEVQSGSYLGEDDIERLEDVYGRTAEPALQVVAGSR
The following text describes a protein:
Function:
Involved in peroxisome biogenesis.
Miscellaneous:
MISCELLANEOUS: Present with 259 molecules/cell in log phase SD medium.
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MPPPSRSRINKTRTLGIVGTAIAVLVTSYYIYQKVTSAKEDNGARPPEGDSVKENKKARKSKCIIMSKSIQGLPIKWEEYAADEVVLLVPTSHTDGSMKQAIGDAFRKTKNEHKIIYCDSMDGLWSCVRRLGKFQCILNSRDFTSSGGSDAAVVPEDIGRFVKFVVDSDVEDVLIDTLCN
The following text describes a protein:
Function:
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
Miscellaneous:
MISCELLANEOUS: Dicyclohexylcarbodiimide (DCDD) binding to the active glutamate residue inhibits ATPase in vitro; MISCELLANEOUS: Was identified as a high-confidence drug target.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDPTIAAGALIGGGLIMAGGAIGAGIGDGVAGNALISGVARQPEAQGRLFTPFFITVGLVEAAYFINLAFMALFVFATPVK
The following text describes a protein:
Function:
Possible regulatory or functional link with the histocompatibility cluster.
Sequence:
MPPFSGKKKKEQLQAKRQRKRDEEERSKLRDREREKLREELMERAEDASEAVLDALLRERANQQHPARGRRARRREEENTVTHRKAVGGDDEDDKSGSGASSDGSNREGGGKLRRSAPPTMMYSADRQHGVRSIFVKESAAVIAARKQLSYQPIPCRTTMPPTGIPFGEWFTFPSSASSAAAVVSAGANSKRGGAWDGGDGAPMCAEEKLALIAAEQQRRMERPLVASAGDALGDVSSSTFFPFAVELPSRGWHVGAEGSAVVADASIVMAGAGDASTQLPSDRPRAADLQAAGSGSATPASEAGQEEVACAGQRSSSQNEASGADSNDVDASAVGTGAAAAKGHNQDDAQDIRSIEKQRFALYTDCVDAYPFPAALVGLEVSSYERNVEVWQQLWRTVELSDILVVVADARYPIIHAHLGLLTYITKKQRKPCVFVLNKEDLVPASTLRCWQRFLYHYLDDLGFSVEPPDAAEQPVEKDTERCNSDGFARGGSTSARIVLRTFTANPRPETAGQPDGDVDVTRRQKNRKKANEHMYEKLRTGRLNVAKHLGGDQCGEESEEDDELRYGATEMFVGMQAAQHALQQDRRAYKELEVVAGKITELLATCRRLGAAARATAQEVNTAAVEWSNAAPSSSPTYATSSLPCAALRAARKHTKAQKRRAARRGSGGGGGGGGGGGMGGALAGDDSGSANSDDAVEDRAPDSPSYLHIGFVGHPNVGKSSLLNCIRGTKVVSVSATPGHTKHMQTIPVPSEHLTLVDCPGLALPVFGVPRPLQAVLGTHQIAQTRDPQTSISFLAAYLPIEKAYGLQRPEHALPEVGWSSYELCEAYAKKRGLFVKHGKGSLDVHRAAIALLQEAYEGRIALFYAPPELNLLQSAWYRERIRPHLLLSVFKPALLAST
The following text describes a protein:
Function:
Probable transcription factor that may be involved in aluminum tolerance.
Subcellular Localization:
Nucleus.
Sequence:
MDSGLGRSSETSLKALPSMASNATRNTDPDQQGVRFSSMDQPPCFARPGQSFPAFPPLFGVQSSSLYLPDDIEAKIGNQFESNPSPNNPTMDWDPQAMLSNLSFLEQKIKQVKDIVQSMSNRESQVAGGSSEAQAKQQLVTADLTCIIIQLISTAGSLLPSMKNPISSNPALRHLSNTLCAPMILGTNCNLRPSANDEATIPDISKTHDYEELMNSLNTTQAESDEMMNCQNPCGGEGSEPIPMEDHDVKESDDGGERENLPPGSYVVLQLEKEEILAPHTHFCLICGKGFKRDANLRMHMRGHGDEYKTAAALAKPSKDSSLESAPVTRYSCPYVGCKRNKEHKKFQPLKTILCVKNHYKRSHCDKSYTCSRCNTKKFSVIADLKTHEKHCGRDKWLCSCGTTFSRKDKLFGHVALFQGHTPALPMDDIKVTGASEQPQGSEAMNTMVGSAGYNFPGSSSDDIPNLDMKMADDPRYFSPLSFDPCFGGLDDFTRPGFDISENPFSFLPSGSCSFGQQNGDS
The following text describes a protein:
Function:
Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the effects of CsrA on csrB RNA by BarA-dependent and BarA-independent mechanisms.
Sequence:
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEACCGEDAVKWCRTNAVDVVLMDMNMPGIGGLEATRKIARSTADIKVIMLTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPAKTETPFASLSERELQIMLMITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLTSQ
The following text describes a protein:
Function:
Probably involved in the binding-dependent system.
Subcellular Localization:
Periplasm.
Sequence:
MKKLVAVTSMILTTFSVQAADLYLYAGAGLKEPVEKIIHQYEQETGNKVTVEYGGSGQILARYNTVKSGDLFLAGSEDYVTKLQKTNDVNNIGTIVLHVPVMAIRKDKISGIDSFKALAESSLRLGIGDSKAMALGKGAEKMFELSGYQKQLNDKIVVKAATVKQLMLYLLNGDVDAAVVGRSGAWKVRDKVELLPSPKGTPEEKVTIGLLFSSKYPKEAQQLFDFFKSPQGVKYFTDEGFLPAK
The following text describes a protein:
Function:
Binds cAMP regulatory element DNA sequence. Plays a role in RNA splicing.
Subcellular Localization:
Nucleus speckle.
Sequence:
MSAQAQMRALLDQLMGTARDGSVYLCLPTSICKGVAEKPHVHRAETKPDRGSSLQMTVSARVTSWTAAPMTSWLGRSVVGAFLFSWNNSSVLPERLKQDHWPDSQEKLHFWPVSQRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKSSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWEHGRSERGAPDWKLESSNGKTASRRSEEKEAGEI
The following text describes a protein:
Function:
Magnesium transporter that may mediate the influx of magnesium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRTKHPQIMGMRPQIPQRVTEEIAMDVDTQQWRAVQSHTRHTKREKKSWLYIDVNGNHQDLEVGKQAIMRRAHLPARDLRLLDPLLSYPSSILGREHAIVVNLEHIKMIITAQEVFLLDAQNPIVAPFVQNLRRRLPASNSTTQNVPPDRCNHAGSGCEDHTNDRERREGRHCTNTPTEQALPFEFQALEVCLEAACQRLDSEAGDLSKAAHHALDALTSRVSIKHLENVRQVKNKLVLITGRAQRVRAEIEQLLDDDGDMTEMYLSTKLVKQQLEVSMRSDTTEQTPAIQSADSGVHGRNHGVVHSTSEGSCLMVTVEDPIKYVHDSNLRDLVPTRSSSRTKRHAAKDHSSSSREEEHPKQRNSPRNQSPLRRSNLHHNMASSAKQFREHLKLGHVSFDAEQVHNNTSLLSSTSSMSRTMGSAIHSKRQHVEELEMLLEAYFVLIDGIIRRVALVIRPPSVYLSINMVHKKHDVFK
The following text describes a protein:
Function:
Catalyzes the release of fatty acids from lysophospholipids. Phospholipase B may well contribute to pathogenicity by abetting the fungus in damaging and traversing host cell membranes, processes which likely increase the rapidity of disseminated infection.
Sequence:
MELLNIIVVLFLSIYTNPIIAWSPTDSYAPGEIQCPSNSSLTRNADSLSPQEQEWLKGRSPIANENLISFLNSANMTDFDPESFINGLNRSIKIGLSFSGGGYRAMLNGAGQLAALDNRTRGGFESGLGGLLQASTYLVGLSGGNWMVGTIAYNNFTSVQHILDQDSIWDLSHSIMNPGGWNIKKTYNYYKNISDALDDKRNAGFDVSITDTWGRALSHQFFPGLDDGGDALTWSTLQDVDVFKNYEMPFPIVVADGRTPGTYVISGNSTVFEFNPFEMGSWDPAVYQFSQVKYLGTEVKDGKPSSNGKCIGGFDNAGFIMGTSSSLFNQFILQINTTSLSSTIKSLLTSILQDLSNDDNDIAVYKPNPFKDSDVAGSKSIASNDTLYLCDGGEDLQNIPLYPLLQEQRQVDVIFAYDNSADTNQYWPNGASMVASYQRQFGNQSNGTSFPYVPDVATFVNSNLTAKPTFFGCDAKNLTSLTTTQNKTSVYDIPLLVYTANRPFSYWSNTSTFQMKYETKERNAIIQNGFEVATRMNLTLDNEWKACVGCAIIRRQQERQGLEQSDQCKKCFEKYCWDGKLTTNADAININFTTEGTTNDTESMKVNSGVLTSVSWSLWAMMLAALSVFILG
The following text describes a protein:
Function:
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Subcellular Localization:
Nucleus.
Sequence:
MQMCRPASSSVLYMPTRWPGGCGATWQSCPSPPPRRTRIPQRPAVMYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYLG
The following text describes a protein:
Function:
The GINS complex plays an essential role in the initiation of DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MFGDTANKLILDAKRSSNLSAIPIYQSDLVKSIVRETNDLNKDAEYLVEEQEQLQETQDQENSKINQCQLFVTHLSMRRNKRCLLAYEKSRADKITEFCWLNIDPIETSTSSSTTSTNTNSNVNQSSSNNAVNPLTKNLSNYTTSLDMNNLNHHEQDFFKQYQDLIMEFKSSFEDIDLSGDLNPPTNIFIDVRVLKDGGEVTTEYGSFNLIKDSQFFVRKSDVERLIQQGYLEEII