lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable).
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MDRGAAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLVQGQKLYFAHHPAFAHFETIDLSQATVAESSCRNLCHSFCVITPQRKITLAAPNRKDMEEWINIIKTIQQGEIYKIPAAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETPRQTPLLKGQVEMDVPRFEAAAIQHLESAATELNKILKAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQIKQNNTAIVSVILKSDLMYDRLSVLIDVLAEEAAATSAEKSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQVEQALDEESRQTISVKNFSSTFFLEDDPEDINQTSPRRRSRRGTLSSISSLKSEDLDNLNLDHLHFTPESIRFKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQMLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEEYAQMQHLARLAENLISKLNDLSKIHQHVSVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETLSRNDAVDVTFSLKGLYDDTTAFLDEKLLRSAEDETALQSALDAMNKEFKKLSEIDWMNPIFVPEEKSSDTDSRSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLWHRRHREDEAEGDDPLTPSRSQL
The following text describes a protein:
Function:
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).
Sequence:
MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDPIDESEEERFEEMPETSNLIDLPTCELGKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQTCENLDNTEGLHHLYEIIRGILFLNKAALFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDVILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLANLGILPALEIVMGMDDLQVRAAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDSDPELGGAVQLMGLLRTLIDPENMLATANKTEKSEFLNFFYNHCMHVLTAPLLANTSEDKLEKDAVFGSIKTSTVCPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLILMNSKHTFLALCALRFMRRIIGLKDEFYNRYIIKGNLFDPVINALLDNGTRYNLLNSAIIELFEFIRVEDIKSLTSHIVENFYKALEPIEYVQTFKGLKTRYEQEKDRQSQKLSSVPSILRSNRFRRDARALEDDEELWFNEDDEEEGEAVVPPVEKTKPEDDFPEGYEKFLETKKAKELEDKENLPKRTSVGAFKFTFSHSVSAANGANSTNSKSVAAHTPPATSNGSSSKNTSLTTTVASTKGSLIGLVDYPDDEDEEEEEDASPRKRPRLGS
The following text describes a protein:
Function:
Catalyzes the formation of 2'-nucleotide products from 2',3'-cyclic substrates. May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
Subcellular Localization:
Melanosome. Membrane; Lipid-anchor.
Sequence:
MLIFTWMAIAFIWDLLGIPRVRSTEEKEIMATEDQVIMEPSLDFPFLNDTKTVEYVGESKTLLLLRGPPGSGKSSLATAISEKYPLKVAICSAEEHIPQGEKPPFSREMLKKAHTDCQQCVKDACKEAYPIVIVDNTNASLLSVKNYSGIGHEFDYVDVLVVPQTSWILDAQELVKRSSRGFPLEDIQRKLEKFQEPIYPLFYGWFVNKTDSETMRGTGETFYERCLSKREFREEFTKHLLPDASGKTPDPENYFSTENYTVGPVMLHCTAFYSNYGEVSQSEAYATQERVKADNGKAFTIKVIGLLVTPRSLGLRLKLDDEELLLWPQDEVNEVAEGGAEETCDLAAGEKSGPCDDECIITHLSPTCGTGSRAHFSLGSGPGVEAVQTGLDLEEIIKMEQEAVRMKRSHIVIALEDATAVGYGEGNWMVYFDEACSTEALFAGYF
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MRGLVLLVGLIFLLAQGSLASDYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAASDTENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEEMNFNATREYGLSYPSQEDVEGAALALVRLQSTYKLDVAQVAQGILNGVKYGSDMSWQDCFELGQQLFEMEDYNNTKVWLRESMERLRRQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIRNWHLGDKGTAPPEDIDDVYLPKHSDSYSLSQEFAKYEKVCRGEVHPIVRQELRCRYSRGNHPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPGGQLKKSAFRVSKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRDPNHYPAEEGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPVLKGSKWIGNVWIHEVTQTFARPCDVFRDHEVSLEYEIIK
The following text describes a protein:
Function:
tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. Adds the terminal adenosine residue to tRNA.
Sequence:
MFRRRPPLPPFPPGAALVGGAVRDWLRGVRSADYDWAHPDPAAGARALAALVGGAAFPLDEERGYWRVTAGEVQHDFVPLPPNLEDDLRRRDFTVNAIALREGRRLVDPLGGQQDLKRRVLRMVSEDNLRADPLRAWRAARFVTTLSFTLEPQTEQAVRQVAADLKAGRLPFPAWERVRDELHALLRSPDAARGILTLEALGLLDLTLPELREGQGLTQGGFHHLDVFEHGVEALHQLLTRRPDADLLLRWATLLHDVGKPRTFARDPDTGRRSFHGHDRVGAELTTQILTRLKLPGADVKRAAALVKAHMVQLPADDAQARRFVHRRRELLPDLLSLMLADREAARGPSSSELGRFAYMLAMERVLAALEEQPAAPPPLLSGKEVMALLGLTPGPRVGEVLRALAEARALGEVGTPQEARAFVQRWAEETPGS
The following text describes a protein:
Function:
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Sequence:
MHELSYANAMLEAILNSIKKEEEKGKKIKKVTEINLEVGELTFINVEQLKFAFEVIAEGTVCEGAKINVEFIKPKCKCLDCGYEGEPEILDEFEVYCPKCKSIRLKLSGGKEFNIKNATVEYED
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MVKRSFYEDDEYIINKPGTTTAITPELAEQESVHGQATFIDGMVIRSTPILEKYANSIRHYLHDKLSIWTAELNTQTSAFKNELTTINSEINSLIYEPVLPNLIYILTLTLTGSIFVRQRNIGIRFITPILFGGLSLKYFMPRTFEAISEKYDNVEKENLPQLYEQRQELQRTLKNWGNDVDQGLEQAQVGVYQAVHDFRKLVKEKWE
The following text describes a protein:
Function:
Up-regulates the expression of the hemolysin gene, hlyA, and may promote expression of other virulence determinants in vivo. It may have both positive and negative regulator activities.
Sequence:
MPYLKGAPMNLQEMEKNSAKAVVLLKAMANERRLQILCMLLDNELSVGELSSRLELSQSALSQHLAWLRRDGLVNTRKEAQTVFYTLSSTEVKAMIELLHRLYCQANQ
The following text describes a protein:
Function:
Removes N-terminal dipeptides sequentially from polypeptides (By similarity). Essential for control of distal tip cell migration.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MTAEADLLEGYDEELGGNESQKRDCKGITTAIVVVLLILVMIFAALVFFTPLFAAKSFGSWRLNVSDLRSLRYPYAEFAFTDNNAVVMQSWEGVEIVEDGVSRLIFGRENGAEITPSADRKYFAMMDHAPNPGMNPQNETFHLKIVNNNERLNPLLPFEVEELFRELSDSRITYDIGLRKEESVIQAFKWNGKFNDFVFVESNKIYYQSSPEEEGLTRVSNGGEHTVDGLFDWIYEEEIFGRKDAMWWSTKGDQLAYASYDNHLTKNVSLKTYHRLEPYPIDTNFHYPKTFAKVLPTYTLSIWNKKTEQSRQLDVQLKDSLSYHYLLAVKWLEINGTEQLVSVWTNRYQNEVALTICDWDTAICRLEFEYKYASKRWVTHDDFHSITSFEDTLFFLLPHDKRDNAFQQVASLRLSHGQLRTPKFLNLGEYDVTSINGINKETRTIFFHAAAPKPSHRSLFSYSLADESRNSAYCISCSIKNCTWAQAQMDDQMKTAIVSCKGPAAPHTAIVNLTRMDSDKKTEHANLLYDKTYQNRVEEAGLPVIIKETIKISDDFDALIKLSIPKDIYNRDKHQAIPLIVHVYGGPNDQNTKEATQIGIEEVVASASQAAILRIDGRGSGGRGWKYRSAIYGQLGTVEVEDQIKAIKVVLRLYRHLLDARRVAVFGWSYGGFMTLSMVNEAPEQFFKCAVSVAPVTNFAYYDATYTERYMGDAPLESYSDVTKKLDNFKSTRLLLMHGLLDDNVHFQNSAILIDELQNRGVDFDLMVYPNQAHSLSSRTSHVVGKMTHFLRQCFYTDK
The following text describes a protein:
Function:
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Localization:
Nucleus.
Domain:
The F-box is necessary for the interaction with ASK proteins.
Sequence:
MNNLPEDCIAKILSLTTPLDVCRLSAVSSIFRSAAGSDDVWNHFLPADFPAGFAAPAGLPTRKQLFFSLVDNPLLINGTLLSFSLERKSGNKCYMMAARALNIVWGHEQRYWHWISLPNTRFGEVAELIMVWWLEITGKINITLLSDDTLYAAYFVFKWNHSPYGFRQPVETSLVLADTESTDNVVQPSMISLMQDSGGEEGQSPVLRRDGWYEVELGQFFKRRGDLGEIEMSLKETKGPYEKKGLIVYGIEIRPVP
The following text describes a protein:
Function:
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
Subcellular Localization:
Cell membrane; Lipid-anchor. Cell projection, phagocytic cup. Cytoplasm, cytoskeleton.
Sequence:
MFQLLYCRTASACKYEKRRRRIDRSMIGEPTNFVHTAHVGSGDLFSGMNSVSSIQNQMQSKGGYGGGMAANVQMQLVDTKAG
The following text describes a protein:
Function:
Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions.
Subcellular Localization:
Nucleus.
Sequence:
MASYFAGPAIVPSQHATAAPDNSAVATPSPAKSRDPRFSGSASTTVRHIARSFAAADATGDGDLVIPIDGVDATNVWILGRVVSVVNMEASVSFTLDDGTGKIALTRWIAEDIDAKEVAFVQNGIYLKVQVTLVGFQTKQYGFARAIRPVTNFNEVALHFIECIYLHLENVRQKMQGQFPRSIQANVSTYEMQAQVAHSIQTKSPAYMPFSGGAREHQVDFAPEVNHGRFLSSVQTNTPTHVPFSGGAREQQVHFTPQPNQFSAYPGTGGHQHDLQSMVLEVMQRPDILALENGVHVDEVARRLGMPSAQILATAQRLVNLACLCSTIDDYHFKSIK
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MSKIVKFLKELATPSHSMEFFHKPASNSLLDASELNFVRRNIKREDFGHEVLTGAFGTLKSPVIVESIFHSRIVACEGGDGEEHDILFHTVAEKKPTICLDCGQVFKLKHISSEGEVMYY
The following text describes a protein:
Function:
Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Copper ions provide a large number of enzymatic activites. Oxidizes highly toxic ferrous ions to the ferric state for further incorporation onto apo-transferrins, catalyzes Cu(+) oxidation and promotes the oxidation of biogenic amines such as norepinephrin and serotonin. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. Has glutathione peroxidase-like activity, can remove both hydrogen peroxide and lipid hydroperoxide in the presence of thiols. Also shows NO-oxidase and NO2 synthase activities that determine endocrine NO homeostasis.
Subcellular Localization:
Secreted.
Sequence:
MESGHLLWALLFMQPLWPQLTDGTTRVYYLGIQDVRWNYAPKGRNIITNQPLESDIVAASFLKSDKNRIGNSYKKTIYKEYKDGSYMDEMVQPAWLGFLGPVLRAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGWLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWVYHSHVDAPRDIATGLIGPLITCKRGTLDGSFPPRRQDVDNDFFLLFSVIDENLSWHINENIATYCSDPASVDKEDEDFQKSNRMHAINGFVFGNLPDLSMCAQKRVAWHLFGMGNEVDVHTVFFHGQMLTIRGHRTDVAHIFPATFVSAEMVPQEPGTWLISCQVNSHLQDGMQALYKVKSCSMAPPMNLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSGSDKFFQKSSIRIGGTYWKVRYEAFQDETFQEKVQLEEDKHLGILGPVIRAEVGDTILVIFYNRASQPFSIQPHGVFYEKDSEGTVYNDDSSHSGLVARPFEKVTYRWTVPPHAGPTVQDPACLTWTYFSAADPIRDTNSGLVGPLLVCKAGTLGTDGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDSRLLSEDAKGFQDSNRMHGTFEIYCQAGSHREAGMRAIYNVSLCPGHQANPHQRYQAARIYYIMAEEMEWDYCPDRSWELEWHNQSEKDSYGHIFLSNKDGLLGSRYKKAVFREYTDGTFRVQRPRTGSEEHLGILGPLIRGEVGDILTVVFKNNASRPYSVHAHGVLESSTGWPLAAEPGEVLTYQWNIPERSGPGLNDSACVSWIYYSAVDPIKDMYSGLVGPLAICRKGILEPYGGRRDMNREFALLFLIFDENKSWYLEENVETYGSQDPGRVNLQDETFLESNKMHAINGKLYANLMGLTMYQGERVAWYMMAMGQDIDLHTVHFHAESFLYRSGESYRADVVDLFPGTFEVVEMVASNPGTWLLHCHVTDHVHAGMETVFTVLSQREHLSTTTTIPEEIGKVAIPRNIGEGSVKMLGMQIPIKDIEMLTSVLIAMGVILLLIALVLGGVVWYQHRQRKLRRNRRSILDDSFKLLSLKQ
The following text describes a protein:
Function:
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MKSATWIFLPLLIILAATVILYPNFATRELELAVRKEFISISPEQKKAILSRFEERWNREYKQSDWVISPSPSELKDESFLLVKGRFITSAKINQISQENPELILEAKNKLRPTLVEEWITKGRPLTIKLGLDLQGGMRVAMKGDFEDYASKLRESYIKEIENLNKTVTDPSADEKEKKKAKDRLSEIESYFELSPSRKLLELEKAKLIIDNRLTSQNLTEPQVRIQKDQDSIEVSLPGVTNSSQILEIIQNTETVEYRLEEPENSAGNGLTYASIIQQEENRLLELKRREETDIVQYQNIIKQKLGKAEQDKFLQGLEEKYKIPRDRYRVFAYWARGNHQNSTLLPRKFVVLEKAIALDGRDMRDARPSFENNSFGYIVSFTLTSSGAEKFFEITSQNKGRNLAIVWGDKVVSAPTIRSAIAGGVAQIDGSFTKEEAVDLANVISEGALPIPLRVLEMRFIGPTLGIESIEVGMKAVLIGFVLVMFYMILIYRLSGLVANAALFANIVILSALLSLMGFTLTLPGFAGIILTVGMAVDANVIIYERIKEELRAGKSATVAVAQGFDNAFWTIIDSNVTTLISGILMIRLGNGPIKGFAITLCWGIITSLFTSLFLSRLVMDLLVNRLGVQKLQLGFKKLES
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
Sequence:
MSAVDPIADMFSAIKNAIMRRDDFLYVPSSKLKERILDVLKKEGFIQDWEALKGEKYEEEYKKMKELAEKSPNPKMKRYLKQLEEYNKGTQYPIKIYLKYLDPKKRKSAITNIVKVSKGGRRVYAGVRTMPYVKRGLGIAIVSTDAGVMTDHEARRMRKGGEVIAFVW
The following text describes a protein:
Function:
O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis. Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid. Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone. Also able to mediate the methylation of 3-demethylubiquinol into ubiquinol.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MLSFLSLLRYGGKAKPSLAETSEHFDQFAQGWWRGEGPFEVLHAINPIRLHWLKHRLCGQFQRDEKDPLALKGLRLMDVGCGGGLVTEPLCRMGAQVTGIDLVPQNIACAEEHALQQGLSLIYKASSLEDFAASSENEKAFDGVIAFEVIEHGPDPEGFLRHAAQILSSGGLLMLSTLNRTFRSYLSGIVAAEYLLRWVPRGTHTWQAFLTPSDLRWHLRRAGLEEPAFQGLSFALLRQEWHLSTDLSVNYFASAQKPFEA
The following text describes a protein:
Function:
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9', 'Lys-27' and 'Lys-36' (H3K9me2, H3K27me2, H3K36me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate.
Subcellular Localization:
Nucleus.
Sequence:
MAGAAAAVAAGAAAEAAPAAVAVAAPGRASAAPPPPPVYCVCRQPYDVNRFMIECDICKDWFHGSCVRVEEHHAVDIDLYHCPNCAVLHGSSLMKKRRNWHRHDYTENDDGSKPVQAGTRTFVKELRARVFPSADEIIVKMNGSQLTQRYLEKHGFDVPIMVPKIDDLGLRLPPPTFSVMDVERYVGGDKVIDVIDVARQADSKMKLHNYVKYFMNPNRPKVLNVISLEFSDTKMSELVEVPDIARKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTDENLALYESWSSSVTQSEVYFGGKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKNLLETLKELKEDGFQPQNYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRSIEEENSKPVKSQGILTMCPVSRSSNEAPSPYHSRRKMRKLRDHNVRTPSNLDILELHTREVLKRLEMCPWEEDILSSKLNGRFNKHLQPSSTVPEWRTKDNDLRLLLTNGRIIKDERQPFTDRNLYTADSENEDYMERSKKAKNIKIEQISEGQGNVEPQKPLNMFFESVKSELRNGSSQYSDISDSEESGPDCTVQKNDFTREESESSGDEKKQKISSNFKEESEMTVNLYQTNKKPSRREIPSKRECPTSTSTEEEAIQGMLSMAGLHYTTCLTRQIQSTDYLDERSSLQEHNSCHRSNHEVRQLYQSHKPVEYGQHIKTEEQELGSSSWVRQLTTSRYNPQDPGKAQKHIKKEDSPEFTQKVQSRSYMDGSGSSLQNGKCAQNPSYMPGTCQMSNGNFSPESSGGEASFSLPLHPIKRPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MKTTSQTQKCREASSRKTYMCDTCPKEFETPSKLARHYLTHTGQKPFQCQDCPKHFRQLVHLERHKRTHVRPFQCNICHLNFKNNETLLKHQQRHRFHSSEGKTGKKPSTATQRNSAPDYCTKCRMVFTTEETPLIHQCDFHNVVLNKKLSHCDLCEKVFASRSKLERHILIHTGQKPFSCVICGKAFRQKAHLKIHQITHTQERPFQCSHCFKSFKTSGKLLKHKEVHTQQVHLHNILNKTSRTVVPVESVFFQTVKEERNDVLVYVVPYQCPTCDQCFESQQFLNKHPCFITEDGKPLKGRFLKRTAKQRDRAQLVSNKKETSMSVGRVMKTNQFGDTKSLEPRDPLCQKRESSLDLHKPHLHRKAFKCNTGQSHILQGHLESQELGFCFQEYQINGDTDYNSEKTFISARRESVDESDTLRHFLRGAKGVLRHMNKCDQCEKAFPSLSKLRRHYLIHTGLKPFTCSECGKKFRQSAHLKRHQVTHKRRVTLQRVKETFDDFHQVLVRGTQVGYRYSQNMNYVTDLLENLQACDSSVQYDIPEIKVEIDSPCEFTSIQKLQAVGQQKSRKFVSRDCASKFRSGQPQHSRRTCSVRKSYKCSVCTKVFISPSKLERHYLIHAGQKPFHCFECGKSFRQYPHLKRHQLTHIHVRT
The following text describes a protein:
Function:
Acid phosphatase activity with p-nitrophenyl phosphate (pNPP), D-myoinositol 1-phosphate (Ins(1)P1), phytic acid and Myo-inositol hexakisphosphate. Low or no activity with Glc-6-P and ATP. Confers shoot growth stimulation, enhanced salt and osmotic stress tolerance, and ABA insensitivity. May modulate ascorbic acid (AsA) levels by controlling the input of myoinositol into this branch of AsA biosynthesis.
Subcellular Localization:
Secreted.
Sequence:
MTFLLLLLFCFLSPAISSAHSIPSTLDGPFVPVTVPLDTSLRGQAIDLPDTDPRVRRRVIGFEPEQISLSLSSDHDSIWVSWITGEFQIGKKVKPLDPTSINSVVQFGTLRHSLSHEAKGHSLVYSQLYPFDGLLNYTSGIIHHVRITGLKPSTIYYYRCGDPSRRAMSKIHHFRTMPVSSPSSYPGRIAVVGDLGLTYNTTDTISHLIHNSPDLILLIGDVSYANLYLTNGTSSDCYSCSFPETPIHETYQPRWDYWGRFMENLTSKVPLMVIEGNHEIELQAENKTFEAYSSRFAFPFNESGSSSTLYYSFNAGGIHFVMLGAYIAYDKSAEQYEWLKKDLAKVDRSVTPWLVASWHPPWYSSYTAHYREAECMKEAMEELLYSYGTDIVFNGHVHAYERSNRVYNYELDPCGPVYIVIGDGGNREKMAIEHADDPGKCPEPLTTPDPVMGGFCAWNFTPSDKFCWDRQPDYSALRESSFGHGILEMKNETWALWTWYRNQDSSSEVGDQIYIVRQPDRCPLHHRLVNHC
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MSKDTKDAKTPSEAAGLLMSIVRALSSSANVQQRDDEKIRLEKAFKESDRKLDNMITDHLTDLTSIIQAFSKISSRISCSQEKIKLVKENLLSCKNLLHCKRDELRRLWVEGIQYKTVSSMMDEVENIKNVHDKLRKHLESRHYLSFTTLLMSSLEMLNNDLSCVEGLKDIKNELVSKKDELYNKLTEELDNLIYVKSTLGVVKHFQRQGSQRQSKSKPQLKSGLKSKEIIEDDSIIQDDNAIKLLMNVDTKSVSDSTEPVTEDINNSPDSNIVNFISILIESLAKLNRMPDAVEYLKRRMGPGLVAIVRRASQQVADYAYVEGEELSQLQQPQYLLEMLELIFKQFHVVSKVHEILLANMRRIKNVKSSQGDFNLYDIMDLWSKIQSVMQSLLCSYLDVDESASRLSSSPNDRCPENITAIYNSLKSFLAEAEKTTKVAHGSLSLQAYIKEFVEGVFLIRVQNEADMIISQAAKSPEMKKKLADQHTQRAFSLVKPILQSSVIVAELLQNTCTLMRDLPDYSSKFMNLICKSLQEYLNVCQASYKECINPELEEKKVMSALWMKDDDISRFLRSLPNFLDLKKVSVSDEEQTQISDEDLRAMNAKESTVLTNNLLTGNESNVLFNEIISDTAILRTLGNLCESMEWFSSRIKDFSNGLESGTGARFIVSATDSAKQIPDGSSHYQVNKDTLVALKSLSRHYEDLSEVCLLVLHLEARVHCFHHLLRIPKSDYCGVIDKLEPDENVLRLNKDLISLEEVMSQSLQQPKFSYVFQGLGHLISTILVGSAQVLKRINENGVKKMCRNVHAVQQCLSNITGNREPDLDHARQFYELLYLSPDEVMKACFERGKQFTEHEYTILLQLNHRSTTGSTEADLNVRLKKLASILADSSL
The following text describes a protein:
Function:
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate to form deamido-NAD(+) (NaAD). Key enzyme in both de novo and salvage pathways for NAD(+) biosynthesis. Predominantly acts in the salvage pathways via NMN.
Subcellular Localization:
Nucleus.
Sequence:
MDPKLAPNFVRPSDKRPTAYRSPAPAQASLIPNIAPIQPYVLEDSQHEIDLPQDSPRLLPSRTNSRDSLVGLEQIALTLKHHSKHNPKDSNYHPAPVNIPRIHSELNMSDSSPDRCEKIDEVDLEVSPNEIQTNFSKFSLGDQALPPTTVEEAMAPTSPKSPKEPQVHTETGTADSSSRTPPYLLDNSGLRPIIQSADLEEVPIGVSRQARDLDHYKFPTHRLSEVMIEETKSPLVIVACGSFSPITYLHLRMFEMAMDSIREQTRFEVIGGYYSPVSDNYNKPGLAPAHHRVRMCELACERTSSWLMVDAWESLQPTYQRTATVLDHFNEEINIKRGGIKTVSGKRKGVKIMLLAGGDLIESMGEPNVWEERDLHHILGRYGCLIVERTGADVRSFLLSHDIMYEHRRNVLVIKQLIYNDISSTKVRLFIRRGMSVQYLIPNSVIRYIQEHRLYVGETEPVKQVLYDRE
The following text describes a protein:
Function:
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
Subcellular Localization:
Cytoplasm.
Sequence:
MREYDIVVIGSGPGGQKAAIASAKLGKSVAIVERGRMLGGVCVNTGTIPSKTLREAVLYLTGMNQRELYGASYRVKDRITPADLLARTQHVIGKEVDVVRNQLMRNRVDLIVGHGRFIDPHTILVEDQARREKTTVTGDYIIIATGTRPARPSGVEFDEERVLDSDGILDLKSLPSSMVVVGAGVIGIEYASMFAALGTKVTVVEKRDNMLDFCDPEVVEALKFHLRDLAVTFRFGEEVTAVDVGSAGTVTTLASGKQIPAETVMYSAGRQGQTDHLDLHNAGLEVQGRGRIFVDDRFQTKVDHIYAVGDVIGFPALAATSMEQGRLAAYHAFGEPTDGITELQPIGIYSIPEVSYVGATEVELTKSSIPYEVGVARYRELARGQIAGDSYGMLKLLVSTEDLKLLGVHIFGTSATEMVHIGQAVMGCGGSVEYLVDAVFNYPTFSEAYKNAALDVMNKMRALNQFRR
The following text describes a protein:
Function:
Transcription factor that binds to the E box motif 5'-CACGTG-3', probably in a heterodimeric complex with mxl-2. Involved in modulating longevity in response to TOR signaling, dietary restriction, the decline in protein homeostasis associated with normal aging, germline signaling and the insulin-like signaling pathway. Plays a role in autophagy. Involved in regulating migration of the ray 1 precursor cells in the male tail, acting in concert with Wnt and semaphorin signaling pathways. Regulates transcription of genes encoding extracellular matrix (ECM) components which may contribute to the substratum required for migration of the neighboring ray 1 precursor cells. Involved in repressing infection by the microsporidian pathogen N.parisii, probably acting independently of its canonical partner, mxl-2.
Subcellular Localization:
Nucleus. Cytoplasm. Mitochondrion. Note=Nuclear localization is promoted by conditions of dietary restriction or reduced insulin-like/IGF-1 signaling in a pha-4-dependent manner.
Sequence:
MSRGQIIHSGHFMCSNPHDDLVQDEDEEDVEVDVVEDDDKSMEASSSVHHKNKALDEKPVTFYKFGVGKTQSIAIDVSLNKLNKCIKVAYNKMTTPKWKDFKGLRLHWKQRVRLNNVIWRAYYIEFRKKQPEKPKKPFCYFAVPDDDTTHQKIEGSIVEGMYWKRKMEGVCAQYKRWRIRSKHNLVTDKGGMVATCSSTSVSSMTGELKRKRKHTVPKETIESKLRSYEPPVKLQRSQTPKHTISDEFAWDFDDLDNVFTDDFLNSLSEPYMFPDPRDVYSGNNADIMQPGLLPLQPTIEDIMMSLGDDMPDSPPFHNDRDTMRTPTNDQPSISAQQIPQMRRSASSSASLHQMQVAQAQAQSISQISQPSQQLQHQIQIQQPVAARPHEFMASSIMMDYRLMPTRQSSAITSQMLMLSQSASTLSSQPQYATSTHYSTNNSFLPIRNTMTNQHHLGHTSQHSPWNKQQQSNFLVSLPHQSHVERILNNQPPLVPPPSRSNLLPTQNDPYLPQFLQSTQPTPQPQSHDPMMAPSRSWWLDSPLTASVQSPLSVATPLPLANQTGPQTPLGQLIGSADNGFLFGGNNTPGGFKMSGTTSGVPTLSQRLEQPPISRTSTIFGNVENKPERIFTSLTSQNTPTPSPLDISSLSRLRTSSLNESWKMSHIVEGSPTYQAFAASVTTKPSILESPSTSGDISGPASVPVQASQHPPKIITPPSASSKRKEQEAAMAPLVNRQQSCDVNLLNGKMAVKVEEKSGRHYLPTTPTELKEVTKEEPLLMSAPSSVKSMRRQAPDSTLHPEERKRILHLHAEQNRRSALKDGFDQLMDIIPDLYSGGVKPTNAVVLAKSADHIRRLQAEKWDKTQKIDEAKAKIEKLNQKITSLQSNLPQSSAPSSSSQVDSKTSLETFFDRYVKEGAKKNWRFWVMSQMLKPICVTQTNSFASSVAGDSSSRNEVAASCSDWLNKNWKATELRPLASTLLVSLATNSSILAEPDTLPDYVMQQLKNPF
The following text describes a protein:
Function:
Part of the ABC transporter complex TcyJKLMN involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in cystathionine, djenkolate, and S-methylcysteine transport.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEKAFDMNMIGDFVPTLTAYLPVTLYILTLSLLFGFVLGLFLALPRIYNIPIVNQLAKVYISFFRGTPIMVQLFIVFYGIPALTGLIGIDTSKMDPFYAAVATYALSNAAAAAEIIRAGVGSVDKGQTEAAYSIGLSGSQAFRRIVLPQALVQAFPNMGNMVISSLKDTSLAFSIGVMDMSGRGQTLITSSNHSLEVYIALSIVYYAVAVLFEWFFRVAEKRIKKNQTRIVTVFDMNIH
The following text describes a protein:
Function:
Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase.
Subcellular Localization:
Nucleus.
Sequence:
MANSDDDDAFLYSDEEQEVEKQGPKVKRVKFADEESNKEEDKTNEKEQQQQKQEASNSESGSGSGSESDSGSESDDDIDIIIRDTQPTKSKSSGTTIIGNEALSEMTDPEESTSSSSTTAAAGTTTINKRQSSSTINLESVPRYQQEEDGEGDGTLITQLDIETLKLKPWRAPGVDVSDYFNYGFDEFTWLAYCHKQDKLRGEFNPQKVMENIMKGPGGAVGANGTNGINLGDKTGQQQQQQQQQQQQQQQQQPPQPPMGMMMPPPGFMANMPMPPMGSMPPMPNMANMPNMANMPNMANMPPPPPGFNGQFPAPYNIPHTMNQKQ