lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the dehydration of 2-methylcitrate (2-MC) to yield the cis isomer of 2-methyl-aconitate. It is also able to catalyze the dehydration of citrate and the hydration of cis-aconitate at a lower rate. Due to its broad substrate specificity, it seems to be responsible for the residual aconitase activity of the acnAB-null mutant.
Miscellaneous:
MISCELLANEOUS: PrpD catalyzes an unusual syn elimination, whereas the addition of water by AcnB to cis-2-methylaconitate occurs in the usual anti manner.
Sequence:
MSAQINNIRPEFDREIVDIVDYVMNYEISSKVAYDTAHYCLLDTLGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFNDTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTAMIKAHEIQGCIALENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTGTRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSYVMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDKKGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFTADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQFPTRQQQRILEVSLDRARLEQMPVNEYLDLYVI
The following text describes a protein:
Function:
Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Localizes to chromatin.
Sequence:
MARVFRRECHRVLDSERTTIQGADGMLMVPQLAIAGVNKQERGDFGVALSEVLAVWKYFLLDKLQLSHKDIPLPQSYDLIRKEYDCFLKRTNTVDLIDVFSMFKELRLNEDPEEPLTTMQMFQFLFGENESSEKPSQPVCPATPSCKAADCSPQIQRVVRRVFCSYLDLLVNSKNDLALTYTLDNPNRSLGHTAFTDLRHAACDSASSLFLTVTSFVRAIQLGGKGYAPPESHPLRKHVKGLSEFLNFVDQCQDILGETPNPREAGCKLVSSIRAALVKGRSAGDPVYLAAEESTKSLKERIGQIHAMHTQSTVGTGISPARPKAYAINHATAYGGRETVKVLMALLDEEALALPCRNKAELLSEDHAALNGSTGACLLALYKSPEAPTGSSPKSLRNRVLSQQEHIKSKVVRPTIRSQFACTYKEEELPLNRVLEFPSTSQIPTCVHPAPKKASSESDNGMDNRFKEATNLRCEGPGQSALGEHSGNAWNQTGGKSTQPEPLRRATGTLKRKLANRECTEQGREENQPPQKRPPAKAATGGPGKRNNKAVSKKLIAGQGKLTGFFRL
The following text describes a protein:
Function:
Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
Sequence:
MKLNPRQDEAVKYVSGPCLVLAGAGSGKTRVITNKIAYLVQQCGYKARNIAAVTFTNKAAREMKERVAQTLGKGESRGLMVSTFHTLGLNIIRREFKALGLKAGFSLFDDQDQLALLKELTEKQLDGDKDLLRLLLSTISNWKNDMLTPPQAKAMAKGEQQLLFAHCFELYQKQMQSYNALDFDDLILLPVLLLRSNEEVRQRWQNRIRYLLVDEYQDTNTSQYELVKLLVGERGRLTVVGDDDQSIYSWRGAKPQNLVLLGEDFPSLKLIKLEQNYRSTSRILRAANILIANNPHVYQKALFSELAEGEKLKVILANNEDHEAERVIAEIIAHKFLNRTEYRDYAILYRGNHQSRLIEKSLTQNRVPYKLSGGTSFFARAEIKDIMAYLRVLVNPDDDNAFLRIVNTPKREIGPATLEKLGSYANMRGKSLFTASFELGLEQHLSGRGLENLRRFTEWLVAIADNAERGNTVEAVRALVRDIRYEDWLYETSASPKAAEMRMKNVSDLYSWIVADLEGDNPDQQEKTLKEVVQRLTLRDMMERGEENDDSDAVQLMTLHASKGLEFPYVYLIGAEEGILPHQTSIDEENVEEERRLMYVGITRAQRELTFIVCKERRQFGELIKPSQSRFLDELPQDDIEWEVKKKPVTQEERMAKGQAHIANLRAMFKK
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MQSKSETANQLRSDPHSFTPNNAYSEPWWRGIQYNPVPQAMLGVNASNSSSLERPNGDSESSEEDDDATKESQPTAPNQSGNYGQDHQAMQHSSSSAPLVRDDCLTQAPQVELVGHSIGYTPFIGMPHARMALPLEMAQEPVYVNAKQYQGILRRRQARAKAELEKKLIKVRKPYLHESRHQHAIRRARGNGGRFAKKTEVEASNHMNKEKDMGTGQVPLSRSISSSGFGSLPSDSAETWNSPSVQQDARGSQVHERFEERNYANVLQSSSTFCLHSGERVEEGDCSGQQRGSILSEHTSQRRLAIQ
The following text describes a protein:
Function:
Serine protease capable of autoactivation.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MKISIFFAFLGAAVALPVNDDDKIVGGYTCPKHLVPYQVSLHDGISHQCGGSLISDQWVLSAAHCYKRKLQVRLGEHNIHVLEGGEQFIDAEKIIRHPEYNKDTLDNDIMLIKLKSPAVLNSQVSTVSLPRSCASTDAQCLVSGWGNTVSIGGKYPALLQCLEAPVLSASSCKKSYPGQITSNMFCLGFLEGGKDSCDGDSGGPVVCNGEIQGIVSWGSVCAMRGKPGVYTKVCNYLSWIQETMANN
The following text describes a protein:
Function:
Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MESEYSNLIQWYPGHIAKARRQLAEQLKQVDLVLEVLDARIAHSSRHDEIQKLAGERPRLVVLNRADMIPQGMLRSWLKWFAARGEAAYPTNAQNGDGVRAVLKAAQQGAVAVNQRRAGRGMRPRAVRVAVIGFPNVGKSALINRLVGKRAVESAAKPGVTRALRWVRIADVIDLLDSPGILPPRLNDQRAAAKLAICDDIGQAAYTTSRVATLAAELLTPLVPRRLAERFGADPLAVTAEEWLEQVARHKYHGNLDRAAEALLGDFRRGQLGAIALEAPPEEPLVPQAEAECEEG
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Sequence:
MSRVAVITLSSLLLVGLVGSVIFSFVSHNWNKPDPKLANSSKAVQAICDPTDYKDACIKSLAKVKSDDPKELVKGAFASAKVELMEVSNSSTVLKELEKDPKTAEAVKDCKELFQDAIDDFQRSFDEVSKSDWNQVNNTLEDLKIWLSATRTYQETCLDGFENTTGDASSKMRNVLQTAMQMSSNGLAIVNDLSKLFSSLDMNTINKRRLLSNQVNRRLLSVADDGGVLLKDNKEDQRRRRLLSAIKIVGHGKDQVYPEWVDGFRRKLLEATNLAADLKARANVVVAQDGSGKYKTIEEAINEIPRDGKESFIIYIKEGVYNEYLVLLKWMTNVIIIGDGPTKTRITNNKNFVDGTKTFKTATLSVLGDYFMAKDIGIENSAGAIKHQAVAFRAQSDKSIFFNCHFDGYQDTLYAHTYRQFYRDCRITGTIDFIFGDAAAFFQNCSFVVRKPLDNQNCIVTAQGRMERHQPTGIIIHNSKFEADPEYYPLRNQNKAYLGRPWKEYSKTIIMESQIDDLIQPEGWLPWEGDFALDTLYYGEFNNVGDGASLANRVKWRGIKTIAYERAEKFMPPTLFDNDDWIVASGIPYQPTLSSTAEGPMSGIDEDPNAPAGAPSSFTYESSSSGTSSHGSSSGGSFSHSGSSSSLRGSSSSKSSPSTSGGSSSSTTPSIGSSSPGSPTKKSSPSVGGSTPSRTSSKGKPSSNEETPSSSNEKGSHSSTQESTSVSSIEIDAPTPAPDSLLEADLATPSPTPSEGPSLAPFKSQYTILHIPPILSPKRPNSPASSPTEEKKVVVGPVTIRELERVLMSNEEMEGEDDASNDDMSGNVPDGDEPSPAKAELPSPSPSPTVLTVIPSVSPLSSHNGPSPSPSTEEVQDWNPPIGAPEPGPADEADKVQPVVGPPVKSNSGSNFKFEVHALLSGMVMSVALFM
The following text describes a protein:
Function:
There are two distinct cystatins in rice seeds (Oryzacystatin-1 and -2) with different specificities against cysteine proteinases. May be involved in the control of germination by inhibition of endogenous cysteine proteinases. May play a role in defense by inhibiting exogenous proteases such as those present in digestive tracks of insects and nematodes.
Subcellular Localization:
Secreted.
Sequence:
MRKYRVAGLVAALLVLHSLATPSAQAEAHRAGGEGEEKMSSDGGPVLGGVEPVGNENDLHLVDLARFAVTEHNKKANSLLEFEKLVSVKQQVVAGTLYYFTIEVKEGDAKKLYEAKVWEKPWMDFKELQEFKPVDASANA
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDEYLAKKYGSKPKKTKKRKLVEGLDVDTAPITQRQTQQAPPPPRAKGGWKTLSGKAIDPVEETVYRDASGNIISVDDQISVLQQRQQEKEAAERRKKENLLGAVQVEEARKRQAKEEAMKHTKVTVHADDKEYNEERQNRAIYADPAAKFGKATPKASTTSSGGALPSYTGSFPSNRFNIKPGCLWDGNDRSNGFEAKWLSRQEEMKRQADVDYQNEMDF
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSKPPFTHLHVHTQYSLLDGAARLKDMFDACNEMGMSHIAMSDHGNLHGAYDFFHSAKKAGVTPIIGIEAYVAPESRRNKRKIQWGQPHQKRDDVSGSGGYTHKTMWATNSKGLHNLFRLSSDAYAEGWLQKWPRMDKETISQWSEGIVASTGCPSGEVQTRLRLGHFDEALKAAADYQDIFGKDRYFLELMDHGIEIEHRVRDGLLEIGRKLGIPPLVTNDSHYTYAHEATAHDALLCIQTGKNLSDPDRFRFDGTGYYLKSTDEMYAIDSSDAWQEGCANTRLIAEMIDTTGMFEKRDLMPKFDIPEGFTEITWFQEEVRRGMERRFPGGVPEDRQKQAEYEMDVIIQMGFPGYFLVVADFIMWAKNQGIAVGPGRGSAAGSIVAYAMGITDLDPIPHGLIFERFLNPERVSMPDVDIDFDERRRVEVIRYVTEKYGADKVAMIGTYGKIKAKNAIKDSARVLGYPYAMGDRLTKAMPADVLGKGIDLNGITDPTHPRYSEAGEIRSMYESEPDVKKVIDTAKGVEGLVRQMGVHAAGVIMSSEPIVDHAPIWVRHTDGVTITQWDYPQCESLGLLKMDFLGLRNLTIMDDAVKMVKSNKGIDLDLLSLPLDDPTTFELLQRGDTLGVFQFDGGPMRSLLRLMKPDNFEDISAVSALYRPGPMGMDSHTNYALRKNGLQEITPIHKELEEPLQEVLAVTYGLIVYQEQVQKAAQIIAGYSLGEADILRRVMGKKKPDELAKNFVLFQAGARKNGYSDEAIQALWDVLVPFAGYAFNKAHSAAYGLVSYWTGYLKANYPAEYMAALLTSVKDDKDKSAVYLNECRRMGIKVLPPNVNESMSNFAAQGDDVILFGLSAVRNVGTNVVESIIKCRKAKGKYASFPDYLDKVEAVVCNKRTTESLIKAGAFDEMGHTRKGLTAQYEPMIDNVVAVKRKEAEGQFDLFGGMGDEQSDEPGFGLDVVFGEDEWDKTYLLAQEREMLGLYVSDHPLFGLEHVLSDKADAGISQLTGGDFGDGAVVTIGGIISGLQRKMTKQGNAWAIATVEDLAGSLECMFFPATYQLVSTQLVEDAVVFVKGRLDKREDVPRLVAMELMIPDLSNAGTNAPVVLTIPATRITPPMVSRLGEILTHHRGDSEVRIKLQGPTKTTVLRLDRHRVKPDPALFGDLKVLLGPSCLAG
The following text describes a protein:
Function:
Transcriptional activator which promotes cell cycle recovery with CLN2, after pheromone induced G1 arrest, probably inhibiting the ability of STE20 to activate the pheromone response pathway. Binds the promoters of genes that function in cell cycle regulation, cytoskeletal organization, and spindle assembly. May also be involved in stress-resistance.
Miscellaneous:
MISCELLANEOUS: Present with 736 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MKQEPHRQSEEKEKPKGPMAVEREQHTSLSSGTTVTASTGDESTNSRPVESSQTEKSLSLRIRILKQLGFDDIQELNACDTGLVEQFLNVRLINDTKELEKIRESNLAKLNQIIDKCMESDKISDSTLNKILDMSMNRDTNNDNNNHLTIPSPITTKKRKINASELASPRGHRRYRSDIPTVSEVETGVGYPQIHQQPGAYTLPMPANQWMSNPYMQPPQPQVQQIMPQYLYPPGMGPQAQLPTMSSNSESQTPVMSSQFLSLNQHGLYQQNIGAHPVMSMGPQANIYGQQHQLQPGQERDQSRKSFSHRRSQSANISMANFRSPMRNPQPASSQRPVNFLIHTPKHPPPT
The following text describes a protein:
Function:
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.
Subcellular Localization:
Secreted.
Sequence:
MKWVVSFFSIFLLNFSESRTMHRNAYGIASILDSSQCSAEMNLVDLATIFFAQFVQEATYKEVSKMVKDILTVIEKSTGSEQPGGCLENQLPAFLEEICHEKEISEKYGLADCCSQREEERHNCFLAHKKAAPPSIPPFQVAEPVTSCKAYEENRDMFMNRYIYEIARRHPFLYAPTILSLAAHYGKIIPLCCKAENAVECFQTKTSLITKELRESSLLNQHICAVMRNFGPRTFRAITVTKLSQKFSKANFTEIQKLVLDVAHIHEECCRGNVLECLQDGEKIMSYICSQQDILSSKIADCCKLPILELGQCIIHAENDGKPEGLSPNLNRFLEERDFNQFSSREKDLFMARFTYEYSRRHTKLAVPVVLRVAKGYQELLEKCSQSENPLECQDKGEEELEKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTPPELMAFTRKMATAAATCCQLSEDRQLACGEGAADLIIGQLCIRHEETPINPGVGQCCSSSYANRRPCFSSLVVDETYIPSPFSADKFIFHKDLCQAQGVALQTMKQQFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEACFEEEGPKLISKTRAALGV
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MLPLQQQLTGMLVGVLTAVVLFSTANAQHGGWGYSSDNGPATWPNNYPNWCNGQKQSPIDVQSKSAVQKSFPALNFKGFDTPPADAQMRIKNNGHAIQVDLLSKTGKTDNYQISGGGLPGTYNVLQFHFHWGSEHTVNGKRYDAEMHVVTWNSKYPTASAASTVTPDGFAVLSVLLEATSQTANPGMQNIVSQLSNVANKGMNYTYPTSFSVNSLFPADKANYWRYMGSLTTPKCNEVVVWTIFKTSLKISQDQINALKTSCYFNSAGDQDQQQLNNNYRTTNPLNGRTVFDSSNTSGVPQLAPTVLALVIAVLSSTALQL
The following text describes a protein:
Function:
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
Sequence:
MREIVWVHSQRIAPYKTLILNEFCYYPLELDPTPFNALIFTSKNAVFSLLETLKNSPKLKMLQNIPAYALSEPTAKTLQDHHFKVAFMGEKAHGKEFVQEIFPLLEKKSVLYLRAKEIVSSLDTILLEHGIDFKQAVVYENKLKHLTLSEQNALKPKEKSILIFTAISHAKAFLHYFEFLENYTAISIGNTTALYLQEQGIPSYIAKKPSLEACLELALSLRIKEC
The following text describes a protein:
Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MGSLYRSEPMSKCMLYVQNDVAYACMSALGELGVVQFDDMNAGLMAHSKKYSMEVKRCDEMERQLRYFRSMLAEEGIQMGSININPDAPEISKMAEMESVFKESERRLREVSASLTSMKSNRAQLIEMQQLLMKAHIVFQEQQTLQVMAADAPDQRESGNLGFASAVILNDKLMSMERLLWFACRGNVLVRSAVLEENIEDPNTNALVCKAVVFVFFQGDRLKERVKKIMEGYHANVYQCPDSLMDAERLRADVEGKIGDLNAVIEQTTSYRHQQLEEVAKKLAVWIVQIRKMKCIFHTLNTLSMEMAQKYLVGQCWCPNACMDGIKMALKRAADTYGVGPSGAILNSIDQSREVPPTYNITNRFTKVYQSIVNSYGIASYEEINPAPFIIITFPFLFSLMFGDAGHGMLVFLIALWMVLSESKFMGQNSDNEIWNIFFGGRYIILLMGIFSVYSGIMYNDVFAKPINIFGSAWYASPSKYQQHLHTNKDIMLNPLHDNVSDYRGFPFPFGMDPIWMMSQNKITWLNSFKMKVSIIFGVFQMFFGVLLSFFNHRHFRDPLNIFCEFLPEMLFLMCMFGYLVLLIFYKWIAFDATMASCSPSLLINLISMFLYNYSDEPCSPTNFYPKQKDFQTALLLIVALCIPWLLLPKPLILRYKNKKRMMMMMKLKKPLEDIEQGETNMGMELAEDINHNKVPSAKHDQPNEPSALAAAGHGEEFSFGDVFIHQCIHTIEYCLGCISHTASYLRLWALSLAHAELSEVLWKMVLHNGFTLGAGSTNSPSLSCIILFIIWTPWAALTVAILLLMEGLSAFLHTLRLHWVEFQSKFYKGEGTKFTPFSFKKILKHYED
The following text describes a protein:
Function:
Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
Subcellular Localization:
Cell inner membrane; Lipid-anchor; Periplasmic side.
Sequence:
MFKTLALKTSMFKHSVSWLVLVGLAFFISACSKQDEVISLAGSTMGTTYHIKVVPNEHMPTAQLLQAEIDLALEQVNNQMSTYRPNSELSRFNQLPLEQSVEVSPDTIKVVREGMRLYDVTDKALDITLGPLVNLWGFGPDKRPTKVPSQAEIDAAKAKTGIRELSIEGNLLRKHNAHLYVDLSSIAKGFGVDKVASILDKYQATGYLVEIGGELSIKGTKGDASSWRVAIEKPTDEGIAVQQVIEPGTMSMATSGDYRNYYEEAGQRFTHIIDPRTGLPINHKLASVTVLHNECMTADGFATAMMVLGTEASLELAKKEHLAIMLIEKQGEGFKVYYSDAFKPFLK
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MPPCRDPVPALTTIRIRNLVLHKPADATTGRPLFPREARLRGITYSARLCADVELQVDAVAGEQRNPVVNRVFPAVHIGDIPIMVNSLLCNGHDADAFDCGGYFIVKGVDKVVLAQELVWPQALRVLCPKTGSDNWRVELEQVKVELERGDGVLLLSAPGLDTIPLVIVLAALGVSTDRQLLEVMVHDTQDVELTELVRPSIVHAREQMQEFVNSSGVHGGGRDVTSVAVELVGSRIKSVTPLAGPAQEKLGSLLCNTSSSRPADKALLMGYMVRCLCLCVVGRSTADDIHSLKNKRVDLAGDCMFKQMRHLSARFRKTTLKRVLKHVEAGGLDCLTDNLIVDKSVITNGLRAAFSTGIWSLNRNASHYGRICPVETPDDHLAKTMAVFATVSAPRSHDNVLEQLSHCQMQSSQGPLVGWDNVFVNGQWVGATDKPGTLLQAMRNLRRNKLIHPETELARAPSRAEIRIFTDGGRLLRPLLVVDKQRVLLSTREHRRELRARPAHERFDYMLDTGLVELLGAQEESNAVIAVTRREAESSSSFTHVEMHPASLLGVSASAIPFLNHNQSARVTHQAQKHGKQAIGFYTCDILSRMDTNVRQLYYPQQPLVCTRLAQLLARPELANGVNCVVAVACYGGYNQEDSLILNQSSLDRGLFRSTHFRVHRATLDYSSSDIRFCRPETEVARSNSDGIDKLDSDGLPFIGAEMKAADVVIGKAGRRQASKLVDHSSKLRKLEQGWVDQVVCSGGDEEGERHVRVRLREARCPQVGDKFSSMHGQKGVVGMKLRQEELLFTQQGIVPDVVINPHAFPSRQTLAQMLESVRLHHLSEDKMKWRGASGPVHPLTHQPVKDRKREGGTKFGEMERDCLISHGASATVKERLFFVSDRSLVPVCTNCHRLAILNCKQHPRCLFCNPQQRIATLDMPHACKLLSMELRSMGVDMRFRVSQH
The following text describes a protein:
Function:
Stimulates decapping of both stable and unstable mRNA during mRNA decay. Does not affect nonsense-mediated mRNA decay. Required for normal P-body assembly.
Miscellaneous:
MISCELLANEOUS: Present with 2340 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Sequence:
MSQFVGFGVQVELKDGKLIQGKIAKATSKGLTLNDVQFGDGGKSQAFKVRASRLKDLKVLTVASQSGKRKQQRQQQQQNDYNQNRGEHIDWQDDDVSKIKQQEDFDFQRNLGMFNKKDVFAQLKQNDDILPENRLQGHNRKQTQLQQNNYQNDELVIPDAKKDSWNKISSRNEQSTHQSQPQQDAQDDLVLEDDEHEYDVDDIDDPKYLPITQSLNITHLIHSATNSPSINDKTKGTVINDKDQVLAKLGQMIISQSRSNSTSLPAANKQTTIRSKNTKQNIPMATPVQLLEMESITSEFFSINSAGLLENFAVNASFFLKQKLGGRARLRLQNSNPEPLVVILASDSNRSGAKALALGRHLCQTGHIRVITLFTCSQNELQDSMVKKQTDIYKKCGGKIVNSVSSLESAMETLNSPVEIVIDAMQGYDCTLSDLAGTSEVIESRIKSMISWCNKQRGSTKVWSLDIPNGFDAGSGMPDIFFSDRIEATGIICSGWPLIAINNLIANLPSLEDAVLIDIGIPQGAYSQRTSLRKFQNCDLFVTDGSLLLDL
The following text describes a protein:
Function:
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
Sequence:
MLRAGKKTNSQTSTSNDACSLLYINVPDFNCNMSQIENYCIDRFNLLNEVSKLKDTLSAQKSNTSKDNEDFRNLSSRFLGSTKDEQFKIKDELSHYCLRLAMCDSTDRNWFITTESILLANRLNQSDLTTIISSFKGFGWSPVSQEEYEQYQDDLGYLVKKANLNLNEVNNTHFYKLPFQDIPKLIDTKKAIIIKGEAYIYISNFKDMVIHTFKNYMNFALDRIKADKTRIKEEFPELIQFFTTLPKAGDGTNKPQLGNTKHIRKEDVSPLSKTSFPMCMRVMYDSLVETSSLKYEGRLQFGTFLKGIGLPYDEAINFWRIAFSKRVSNTDFDKEYLYNIRHNYGLEGKSTNYSPYSCPRIISKSPHNGDKLVHGCPYIQSLERLEQKLLDLGIDDFQRIQILEATKTSPNVACTKHFNFLHPNNTLTKLINHPNQFYDQSMEYYKTLEEKKSAKQSNNKENENQSIDEK
The following text describes a protein:
Function:
RNA-binding protein that binds to the consensus sequence 5'-CUCUGUAUCUUGU-3' in mRNA 3'-UTRs and modulates mRNA expression and stability. Functions redundantly with puf-6 and puf-7 in oocyte formation and organization, early embryonic cell divisions, and repression of expression of glp-1 and other maternal mRNAs in late oogenesis.
Subcellular Localization:
Cytoplasm. Cytoplasm, P-body. Note=Localizes to perinuclear and cytoplasmic P granules.
Sequence:
MSDSTGRINSKASDSSSISDHQTADLSIFNGSFDGGAFSSSNIPLFNFMGTGNQRFQYSPHPFAKSSDPCRLAALTPSTPKGPLNLTPADFGLADFSVGNESFADFTANNTSFVGNVQSNVRSTRLLPAWAVDNSGNIRDDLTLQDVVSNGSLIDFAMDRTGVKFLERHFPEDHDNEMHFVLFDKLTEQGAVFTSLCRSAAGNFIIQKFVEHATLDEQERLVRKMCDNGLIEMCLDKFACRVVQMSIQKFDVSIAMKLVEKISSLDFLPLCTDQCAIHVLQKVVKLLPISAWSFFVKFLCRDDNLMTVCQDKYGCRLVQQTIDKLSDNPKLHCFNTRLQLLHGLMTSVARNCFRLSSNEFANYVVQYVIKSSGVMEMYRDTIIEKCLLRNILSMSQDKYASHVVEGAFLFAPPLLLSEMMDEIFDGYVKDQETNRDALDILLFHQYGNYVVQQMISICISALLGKEERKMVASEMRLYAKWFDRIKNRVNRHSGRLERFSSGKKIIESLQKLNVPMTMTNEPMPYWAMPTPLMDISAHFMNKLNFQKNSVFDE
The following text describes a protein:
Function:
Involved in the ethylmalonyl-CoA pathway for acetate assimilation. Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to yield beta-methylmalyl-CoA (By similarity).
Sequence:
MSFRLQPPPPARPNRCQLFGPGSRPALFEKMAASAADVVNLDLEDSVAPDDKAQARLNIIEAINTLDWGKKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPVSFEVIIESAAGIAHVEEIAAASPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHEGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPSDKAVAEAREILAAMEAAKARGEGATVYKGRLVDIASIKQAEVIVRQAEMISA
The following text describes a protein:
Function:
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
Subcellular Localization:
Cytoplasm.
Sequence:
MTDREQFFRDVNKIVIKIGTSSITRKGCDHTKENCNIDPAFMESIAAQVYELRKHGKEVILVSSGAIGVGLNELGIAPKPREIPIRQAAAAVGQSILMQDWSRAFSKYGMKVAQILLTYEFYSDRVTYLNLRNSISTLLEYEVVPIINENDCTCTNEIEAIFGDNDKLSAMVASKIDADLLIILSDIDGLFDRNPKTHSDAKLLTLIKKITPEIESYGGDPTNFKGVGGMRTKIKAAKICSMAGCYVVIANSEIEDVVTKILSGEEIGTLFLAERHIQKNRARWIILARASGTVRVDAGAKAAVLGKNSLLPAGIVDIEGTFDRGDVVKLECEGKVFAKGITNYTSKELIKIKGAQTNQIDNILGYNNYDNVIKKENIGILEGIN
The following text describes a protein:
Function:
May be involved in the biogenesis of curli organelles.
Subcellular Localization:
Cell outer membrane.
Sequence:
MRVKHAVVLLMLISPLSWAGTMTFQFRNPNFGGNPNNGAFLLNSAQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIVDIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF
The following text describes a protein:
Function:
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Does not substantially contribute to the rigidity of the cell wall but is necessary for normal hyphal growth and organization. In addition to its functions in the formation of normal cell walls of hyphae, is also involved in conidiophore and conidia development.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell tip. Cell septum. Note=Mainly localizes at the tips of germ tubes, hyphal tips, and forming septa during hyphal growth. Accumulates at the Spitzenkoerper near the hyphal tips. Localization to the hyphal tips depends on conventional kinesin kinA. Polarization occurs by indirect endocytic recycling, involving delivery/exocytosis to apices followed by internalization by the sub-apical endocytic collar of actin patches and subsequent trafficking to TGN cisternae, where it accumulates for about 1 min before being re-delivered to the apex by a RAB11/TRAPPII-dependent pathway. Predominantly localizes at polarized growth sites and between vesicles and metulae, between metulae and phialides, and between phalides and conidia in asexual development.
Domain:
The N-terminal disordered region controls its phosphorylation state and is required for its proper localization to the hyphal tip, but not essential for septum formation.
Sequence:
MAYHGSGPQSPGEHTYDDGHQLRDLSHSNTSYEEEASHGLLSSQQSPFAGPFDDPHQQRGLTASPVQRPTSGYSLTESYAPDAAYHDPYSANQSVYSGHSENPAAAFGVPGRVASPYARSETSSTEAWRQRQAGAAGGGNGLRRYATRKVKLVQGSVLSVDYPVPSAIQNAIQAKYRNDLEGGSEEFTHMRYTAATCDPNEFTLHNGYNLRPAMYNRHTELLIAITYYNEDKTLTARTLHGVMQNIRDIVNLKKSEFWNKGGPAWQKIVVCLVFDGIDPCDKDTLDVLATVGIYQDGVMKRDVDGKETVAHIFEYTTQLSVTPNQQLIRPTDDGPSTLPPVQMMFCLKQKNSKKINSHRWLFNAFGRILNPEVCILLDAGTKPGPKSLLYLWEAFYNDKDLGGACGEIHAMLGKGWKKLLNPLVAAQNFEYKISNILDKPLESSFGYVSVLPGAFSAYRFRAIMGRPLEQYFHGDHTLSKQLGKKGIEGMNIFKKNMFLAEDRILCFELVAKAGSKWHLSYVKASKGETDVPEGAPEFISQRRRWLNGSFAAGIYSLMHFGRMYKSGHNIVRMFFLHLQMLYNWFSTFLTWFSLASYWLTTSVIMDLVGTPSSSNGYTAFPFGKTATPIINTLVKYIYLAFLLLQFILALGNRPKGSKLSYLASFVAFGIIQLYVVVDALYLVVRAFTGGAPMDFNTDDGIGAFLSSFFGSSGAGIIIIALAATFGLYFVASFMYLDPWHMFTSFPAYMAVQSSYINILNVYAFSNWHDVSWGTKGSDKADALPSAKTTGGKGEEAVIEEIDKPQADIDSQFEATVKRALTPYVPPEEKEEKSLDDSYKSFRTRLVTLWLFSNGLLAVCITSEGLDKFGFTNTSTERTSRFFQALLWSNAVVALIRFIGATWFLGKTGLLCCFARR
The following text describes a protein:
Function:
May play a regulatory role in autophagic activity.
Subcellular Localization:
Cytoplasm. Preautophagosomal structure. Note=The BCAS3:PHAF1 complex is recruited to the preautophagosomal structures adjacent to the damaged mitochondria upon mitophagy in a PRKN-PINK1 dependent manner.
Sequence:
MNGKQQVTKKPSTEEDLSFTKFKVVPDVGLKSSQFEFVLGMPINQCIAMIQQHPRMLTKVELKYSKKDPFYQDIIIYIGSTGIRLYFDGLSQLIKLIEVDNLSMITLTYNDTIFSDPNNMATLDRVNEFFGSTHPGSYDDKHNIYVQSWPGLSFCFPYGGENSNLEVRPGFGGNLRSLKYDANSQPKLTKMSIYRGPNPSEPESVDTPFSCYCGQNRTRKVEAIWENGNIVGIDIQFDTQNGRIVDGEYDVSTYTRQIYFGDSVSDVQSILGAPTKVFYKSDDKMKIHRGLHKETLYGPPNFFFNYFVMGLDILFDFVSKRVVKFVLHTNAPGHCDFGMYSRCNFSIFLNDKQYEIRTDSKFDEFSHAFMNDSNPPRPVVLARQEQQPFGSTFCYGIKQIIVERTENGFLTSVTIYDGAKEK
The following text describes a protein:
Function:
Is involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MGQGVAVWRMFHSNRDQESRMKAILEMLQTIEEHGLREKIFHGDKIGLLDIAFGSMLYWLQILEDIVGVQLFDPHKFPGLNAWFEIFKKAPVIEENLPDQDGISLFFKRRREKWLTSA
The following text describes a protein:
Function:
Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.
Subcellular Localization:
Cytoplasm. Cytoplasm, P-body.
Sequence:
MEHLSINDQPPPPPFPQGPGQPGPGMPPPGLLGGGRPPQPQQLPAQMFTTAAQLLDLTDKKLMVALRDGRKLTGILRSWDQFANLVLQQTKERIFVPPGTQSPTQTRGLYADVDRGLFVVRGENVLLMGEIDLDRDDDPPPGYDPADLELVQTLAKQKKAEEKAKEKRKIKKLSTIGFEGENVGEALL
The following text describes a protein:
Function:
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
Subcellular Localization:
Cytoplasm.
Domain:
The two chemically discrete steps of the overall reaction take place at distinct sites on the enzyme, mediated via conformational flexibility of the C-terminal 18 residues.
Sequence:
MLPFATIPATERNSAAQHQDPSPMSQPFDLPALASSLADKSPQDILKAAFEHFGDELWISFSGAEDVVLVDMAWKLNRNVKVFSLDTGRLHPETYRFIDQVREHYGIAIDVLSPDPRLLEPLVKEKGLFSFYRDGHGECCGIRKIEPLKRKLAGVRAWATGQRRDQSPGTRSQVAVLEIDGAFSTPEKPLYKFNPLSSMTSEEVWGYIRMLELPYNSLHERGYISIGCEPCTRPVLPNQHEREGRWWWEEATHKECGLHAGNLISKA