lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit polr2a, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs).
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MNKKSHQQQVLQQQQQQQQQQFQQQHFQQQQQQQQFQQQQQQQQQLQQQQLQQQQQQQIQQQQQIQQQQQQQQQQQQQIQQQQQPQQIQQPQQQLPNFSVPIINQSIISNIKLYSTFETLLLSLSSTDTREQTKAIIYLSSLTINNKSNGIDLVYCIQKQLVVEAHNHIKVLLINLLGDISLDPFIDSFHILNKLLYLIRNEKSKKVLSSCLININKISKSLTFSKGNDVNSSSSSLINQIIEYIEPLLHSTSPLVRRETIVLLGSIVKNLDKESEEIQILLLNYLKDTDFRVREASLKSLSVIFQRGASLSVNKLYQSIILLLLDSFEQVRLECIKLIWIFGNIYPNHIVVSGGTKIRLVDDVFKKICNAVNDSSVIVRNCACKLLGCTYDVSLNYLIQTLSKEVMVWGKGKQYQIGHSSITKQRLQQKQQQQQQQQQQQQQQPPQQQPSQQPNQQPNQQQTNVSGTHIATPEGDFDVVGSDSLNILESGVIGAFIQGLEDEFYEVRSSAIDSMCELSVRNDEFAQKNIDFLVDIFNDEIESVRINSINSLRKIGNNVVIKEEQLHIILANLESSSKEERQSLHRLLTSIHLSNYSCLHATTQALLMNLSRYPYDIHSIFETLKIIGQTNPFTEFIVDDLLRIDPKFASVEPNMDDIFYVAVMVLVLNSCIKNRNILSLLPSFSFQHHLYFKDKYPKYFPQNLQKDSNIILAPTLKYSSVVNNNNNKNNNNNTTTTSIINDNGEINQFLNLTLSLLYGDNNNIINNNNTNNNNNNNNNNNNNNNNNNNNNNDENDENLNYGFQRLFLNQKKEIQLNKLFQECKRNFKRISSICLSLKPTSDFYNKYLKILTTIVSSSRRFKTITTSNQLNHLLYKLNHKFIGVDNNCKLILMEIGIYSFIIEILSTITLSTSSPPTTTTTTSSTSLFTSINSTPIELSNDQINQLTKKLNEYFKFSNDFKLEISTSIKSLLDLFNIKNNNINNNNNIINKKDKKLKENEENEENEENENNENENEKENGKNKEKEKNENDNENENENERPSKIQKTTSELIKTTTTTSTSTSTLIHYNLIEWTDNYIPPILKISNLIKKKSVDVILPIPNDKPIEFLDIFPLKLMINAKIENIRNLDSLFIQSTWQSIHTGQLNSQIHIIPKSAFTPTKPLSYNISCSIYLSLQNIRHNRLSSKESIPLRISIVEQFLNNNNNNNVTIIPLSKFVIFNILPVDNVNLLPNLI
The following text describes a protein:
Function:
Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MTASRGLWLVAAILLLISSGSPVFANDCVPVPQTVEPGRLAALSRGFNADGWINDAAPSRELLQELRRAGMSHVRLPVPAERVMPRFAGKAERDETLRVLDQALKQLTALGYATSVDLHPGERFSRLHKEDPDAALRQMQEAWSGLAGVIRSYPANRIFAELLNEPDVDADRWQTEVETLAVFVRKLLPTTTLVVGPVNWQRADSLPRFRPLPDPNVVYAIHFYDPMVFTHQAHWDAQDPLHDIIDLPYPINASDPKVQAIRRDLEARGATKALGMLDVAIAAAKDRPGADRWLAPALQWQRQFARPIIINEFGVLKAGAPRQSRVRWLAEVTAYARDHCWGWTHWELAQGFGLVDRSTGKPDPDVMRALLGGASRPSRR
The following text describes a protein:
Function:
Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MTSKKIAVLHPDLGIGGAERLIIDVAHAVMIDHKDTTVYTTHYDTNHCFPDTKDLTIKVAAAWVPRSIFGFGHIIFSLFSFLWLTIYAALTSKAEIFIVDQISAWVPILRLLCPRAKIIFYCHFPDLRLASHKSLIRKIYRLPFDLIEKWGIKASHLIYVNSNFTAGVTKQEFGDIPVRVLYPCVDTSRQVERKQSPTPLFVSLNRYERKKDHNLAIKALAKAITKIPDAKLVIAGGYDDRVTENVEHYKELRELAEKLELTEKQVELQRSISDQQKWDLIASATAMIYTPQNEHFGIVPIEAENAGCPVIACNTGGPLETCNVEGCFICEPTVDAFADAMVEAASMKSHDKELRENAERFGFKAFAKQLHDDILKL
The following text describes a protein:
Function:
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MPTTTTTATYGSIPSPSPSTATWQPPTSTPIPTPRSWREFFSLSSLSRPYSYDDAMLRLRHNLTYFQFNYTTTILLIVFLSLLWHPVSMIVFLILLVAWFFLYFSRNGPLVVFNRTLDDRIVICGLGVVSVVGLVATHVGVNVLVALIVGVVVVGLHGSFRVIEDLYVDQESGLLSVVGGTQAAPTRTNYTRIG
The following text describes a protein:
Function:
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation.
Subcellular Localization:
Nucleus.
Sequence:
MPKRKAGGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPRPKKAPAKKGEKVPKGRKGKADAGKEGKNPAENGDVKTDQAQKAEGAGDAKRSVCIFDNCVLLVTEQFEILFLPSFIKMQNFVLLFFFFFELCC
The following text describes a protein:
Function:
Part of the ABC transporter complex GgtABCD involved in the uptake of the osmoprotective compounds glucosylglycerol (GG), sucrose and trehalose. Responsible for energy coupling to the transport system (Probable).
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MASVSFEQVTKQFDDYVAVNNLNLEIEDGEFLVFVGPSGCGKTTSLRLLAGLETVSQGQICIGDRRVNELSPKDRDIAMVFQSYALYPHMSVYENMAFSLDLQGKPKEEIRQRVCSAAELLGIEKLLHRKPKELSGGQRQRVAVGRAIVRKPSVFLMDEPLSNLDAMLRVQARKEISKLHSDLATTFIYVTHDQVEAMTMGDRIAVMKDGILQQVDSPANLYNQPANLFVAGFIGSPAMNFFQVERLSQEGKEKLSLDGVVLPMPDSVAKNGDRPLTLGIRPENIYHPQYLPLEIEPMELPATVNLVEMMGNELIVYAQTPAGTEFVARIDPRVNIKQKDSVKFVVDTQRFYYFDREMETAIF
The following text describes a protein:
Function:
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MSLPSAANANAAAAARRKVPNLNIVISCPECKVYPPKVVERFSEGDIVCALCGLVLSDRIVDTRSEWRTFSNDDQNGDDPSRVGEASNPLLDGNHLSTRIGQVQGSDVKLTRELNRAQSKSIVDKKDNELQAAYAKITMMCDAAELPRIVKDCAKEAYKLCFEERALKGKSQESIMASVILVGCRRAEVGRTFKEILSLTNVRKKEIGKTFNIIKKILREKNDSGFANVDTANISTGQTNAETFIPRFCSHLGLSVQVANAAEYIAKHAKDINVLAGRSPLTIAASAIYMANLLFRYNITPSQISATLQVTEGTVKGGYKILYEHKEKVVDPELITTGKVSFDDLPKVSDKGDK
The following text describes a protein:
Function:
This protein is a component of the leucine, isoleucine, valine, (threonine) transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids.
Subcellular Localization:
Periplasm.
Sequence:
MNIKGKALLAGCIALAFSNMALAEDIKVAVVGAMSGPVAQYGDQEFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVAVANKVVNDGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGLDSDQGPTAAKYILEKVKPQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEKDFSTLVARLKKENIDFVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGESAEGLLVTKPKNYDQVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQSDDPAEIAKYLKANSVDTVMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MLSQYMEEFEQEPFEVGEFIERLTWRTNNELQNSEDFHPVALHDTFIQTIKDLKILQEKQQSKCERLEESLRQEKESHAKKIAKLQERHQTAIDVFGQLDEKINSVAGKIMHLGEQLENVNTPRSRSVEAQKLLNFMSEFLAAGPVIVNDIFADAARLSEAADVIQKLYAISQDLPPGNFAESKRKIEKKYDEVERRLIEEFATAQKSEDIERMKTLAQILSQFKGYTQCVDAYIEQSQMQPYSGKDIFIGIVPLCKHHYEIIQKVFANPQQVMSKFILNIYQLKLHQYAMTKLEDKKDEEKYLRTLYELYSRTLKLSTDLQIYMSTIDDDLLQKLTQQIFIKHLAGYAEMETKCLTAKCSTELEKFYASKKHQKTATTKGFRRNMEVLIATRANINIAAIEDYGGETFLSEELAINMLQEAKASLKRCRLLSNETELPGNAIKLNDILLRFLMHEHVDYALELGLQAVPLAEGRVFPQLYFFDVVQKTNIIVHLLDKLCHTSVIPCVSNTPKYSDYVFKKRILMEQIETKLDQGLDRSISAVIGWVKVYLQYEQKKTDYKPETDVDTISSAACLQVVQNLQPVIVQIKKCVDGENLQNVLTEFGTRLHRVIYDHLQTMQFNTAGAMCAICDVNEYRKCIRELDSPLVTQLFDILHALCNLLLVKPQNLQEVCTGDTLNYLDKSVVRQFIQLRTDFRIIKNTNYLKGIIE
The following text describes a protein:
Function:
Chromatin reader protein, involved in positively modulating the rate of age-related behavioral deterioration. Positively modulates the level of global trimethylated 'Lys-9' of histone H3 (H3K9me3), but not of H3K9me2 or H3K9me1. May repress the expression of mitochondrial function-related genes by occupying their promoter regions, working in concert with histone methyltransferase, set-6. Involved in modulation of the mitochondrial unfolded protein response (UPR). Negatively regulates expression of bas-1, a serotonin (5-HT) and dopamine synthesizing enzyme (DOPA decarboxylase), with aging. Negatively modulates levels of endogenous 5-HT and dopamine with aging. Involved in modulating longevity, probably as a result of enhanced stress resistance via mechanisms related to dietary restriction and mitochondrial function.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MSDNSSNQFLLLLAAAQQQQQQQLLQQQLAKIQKATASSPSKSTNGTSASTSAVPSTSGTSSSQNEAAQLQNLAKMQQIQQLAQFGALMAAQKKQQEKAAADKAKEKEKEKQKAAAAAAAAAAKASASTSSASAIPGLSPEMLAAWQQAIQMQALQQMMMTPQKSQMEEAIKKMMDMAKKKPAGVASTSSASTSSSTPSTSSASITSSNNNAANNAASNMMNNVMWQLVAAQMQQKQQQQQKDTQKKADQAKKAKELAKQQQKEQDVKNKQQEEILKFLMAQHQLNHQKKHEKKQADAAALAAKVLAAHRAALESDSPEEGKKTNEAMLRLPLQLGWRRQTCVRSIASAGVKGDVSYFAPCGKKLSTYSEVVRYLTKNSIHYITRDNFLFNTKLVIGEFIVPKQTEADETQQEREFAMFTEDDINKELTRLNVLKFVPKIQASTSNGVHEDDIKMSKIEEPDEPLDPSELNDEFTEELVHSQIMSNGVDECKIREREADDLLVNINDVRHLPDFSRIGNQCLSSQGFADALMVHEFVQNFGHVLGIDLEIAPKLESLCAGLDGDANHAEQTLQLTRQLLRLALEFPGMGNEKRFGQGGGEMGLDRENFSEVMRLFLIDKGKRGEELSQPLLTCNFLSISPEQKASILAFLCDELVCSRNVVTEIDKNLDEISRLKGEKWMREGKARALRSARSKKKNDEKVVVVKEEQNHESDSEPPTRPDTPKKATVAPPTVVSVSPVSAAQQQQRKFTPGLGQCEVLTEQEESMSLQQMDSLIGDLHQEAQNINQKIHDTGLKIRSFPFGTDRFHRNYWMLAHTDKVIIESLATTSVNNPACNANEYASKDPPTLEQRVPGACETIDLDVIACVEDLVDDVVLLRAKADKKTRKRYRRIENHMKRGWWTMQNRDCVESLRSCMLSRGIRERALHRLLTKPWFLNELKFGTITIEPVGEKSDLELVRRQGWTRLNTAIDKLQCHLKMSDVSKPLPSITPFETQKPIVVPPTMALAQIVKDDMAWKVIDEEVDGQELDETIIRQKIIETADMVQPKFWRPKFQKLEDQDTCQLFEDWKSYVSTEAQTTSQLMVALQTLEGMIMWERSSREALCQICKSMDGDEMLVCDGCESGCHMECFRPRMTKVPEGDWFCQRCREEKSGRPMCMFCSRETGNLHQCQRCAYHVHQECSQDGPKEAINPETFICGHCQEMKQMRFVKRLILRSESEERELEDDNHAENGENTKNGHMNGMNGAIAIGVHNQQNGVKGNLKRKLEVPSIGGLPKNMNKELCQLMLDELVVQANALPFLEPVNPKLVPGYKMIISKPMDLKTIRQKNEKLIYETPEDFAEDIELMFANCRQFNIDHSEIGRAGISLHKFFQKRWKQLKYNFTKRLRRLHR
The following text describes a protein:
Function:
Ubiquitin-like modifier involved in autophagosomes formation. May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
Sequence:
MLGLHGLGWAGPKRRLLPYILSFFFFVPTTDNFTDLTIADPHSPRTSKAKQSDRFREARSRRMKAFKKEFTLEERANESAAMIANYPDRIPVIVERFSRSSLPEMEKRKYLVPREMPVGQFIFILRSRLHLSPGTALFVFVNNTLPQTANLMGSVYDVYKDKEDGFLYMCYSSEKTFGSSACN
The following text describes a protein:
Function:
Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit polr2a, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs).
Subcellular Localization:
Nucleus. Cytoplasm. Nucleus membrane; Multi-pass membrane protein.
Sequence:
MKEEETIEISEKEKDKERNDNQDTLTISWIEDWRNEETATKNENNKNNNSDGDSDDDDYYDDDEEIKNSRYNLFLEKILTLESNSNLKNILSLNINFKKDNKKSKETDTAATTTTTTTTTTTTTTTTTPTATANKKYIRTNNLLNNNNSSSSSSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGENITYITSPLSNESLESTEECCFFLVHLPITKDLIFNQFTCLLIHLFQIEYNNTIIINNATSSSSVNSLNRSYNNSNNNNNNNYNSYNNRGNNYNNNNQQQQQQQNPNLKIRDLEGYQDCSHLKKLCLTIHDYLTQLLQRNPLIWYDSIINWSLSTLTIITRLLIILKNNKSQQQQQQQQQQQQQQQQQQQQQQQTKNKTQFPPPPPPPLRQPITPISAMVRERLDFYSFRSLLSLVLHLTRIFSIETFIEKSNVTQFLDITSKSSSSSSSSSSSSSSSSSSSSSSSSSSSSSKTIKPKKLPIYELGWILCHLGKKNPSLILGLTFNHYLKNIGLNSNNNNNKVNSKSQYIQDINCFQILEFLALQPSSYLSIIFQQHIDKIISNHKSNKNKNNTQFLKDIKTFLMLITKDDVFLSIGLPIILDKLSPFGINQFDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSIKEDNSSEKDIESIKEILEKVLLGNSQVISFYSKRILLVLYHCCFGDSNDITFSSYSTSTLLQIKNQTRYNVSIKLLTSIVKDRLEKQLINKLYSPILNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQQQQQQSQEIENSTFINNLNQDENITFYLNQIQCNNNNNNNNNNNNNNNNKLIKEKNNIIIKLISLIGMDSIYSSLIILNHIISKLKSNQFIQYFYTLVEQFQAVNSNTIEFFINDLFKSIDSFSHDDLITLLNNLLELVKITPPPSSSSPSNLSIYNETLKCISSNWVVLLKLIKHPNLIESNKMMSIEILYHSFNNRYNNNNNNSQSIQQLEISNNNNNIKKKEIYPSTLLSDKEMLEIRVLLEKILNLIFKSFKEKNSFERLKKFEIYKNLYLLICNGSSVYFSSTIDLILDSLFSKKTDMIIKLPILCALSPANTLPPPNYPANLVNAGSGSGNFGNGDDDDDEYGDDEYGANRNEKEELYFKQIINPSLPLSQPLIMLPMQSSLLEINYERKYYHYKFNDMNNPNHIPFTNKPKNLKKRIENNQSSAIDTTNNNNKNNEILTYKKQRMKKKKQSIQQNGNINNEQQQEEDDNDDADDQNEQDDYEKYNILNNENDLQSFIKSLVLYDGGGGSGFNNHGDINDRLQILTNQFLLRVSSPYLEPSYENYQEILPKQSHYERDIFIRNLFQQNPFLYRVLEIISIDGRELTKCLEVIKSLLVNEISYWYQCRNSYSESPIKSSHYHTTILLVKALINAEFIIHPLNLSLELFDKIKAEEISYILTSIWNFIKDYQPNPSQYQSSSSSSSSSSPPSNNTIIPTFKRVFSNCNTTPYSLTLKAIFHNHIKELCFHYARFFPKKYY
The following text describes a protein:
Function:
Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (By similarity). Might play a redundant role in the regulation of T cell receptor signaling. Might promote apoptosis in T cells (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type III membrane protein. Postsynaptic cell membrane; Single-pass type III membrane protein. Postsynaptic density membrane. Cytoplasm, perinuclear region. Synapse. Cell projection, dendrite. Nucleus. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities (PSD). Accumulates in spines along with synapse maturation and colocalizes with DLG4 in a punctate pattern. Translocates from synapses to nuclei following NMDA receptor activity (By similarity).
Sequence:
MVMSQGTYTFLTCFAGFWLIWGLIVLLCCFCSFLRRRLKRRQEERLREQNLRALELEPLELEGSLAGSPPGLAPPPPPHRSRLEAPVHAHSHVHVHPLLHHGPAPPHAHPHPHHHALPHPPPPHLAVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAAPCPALCLQAERSRRVFPSWTDSELSSREPLEHGAWRLPVSIPLFGRTTAV
The following text describes a protein:
Function:
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
Subcellular Localization:
Cytoplasm.
Sequence:
MEEDLPTEFDLIVIGTGLTESIIAAAASRIGKTVLHLDTNDYYGGYWASFNLEAFRKYLNSSATQISTAVEAINNNFLPLQAQPTLVRNVQVQWYNFTEKGDVDGWNREKIEQEFRKFNIDLVPKLLYARGSMVELLISSNICRYAEFRALDRVATVWDGRITTVPCSRSDVFTNKEVNVVEKRLLMKFLQSCVTYEEDSEAKEELDGKTFLEHLQSHKLTPNLTHYVLCAIAMGNARTPCREGIAAVKKFLMSLGHYGNSPFLFPVYGCGEIPQCFCRLCAVFGGIYCLNKAVEGIHFEQCNEGFKYDSVKCGKQNITSKGLVVGQGYMSRAVFSKSTPAEGAAQKLCGNLARAVILTNVPLGGASQNPGGGGVAIMKLPPANNHQEGATILQMSHPSGTCPKAIYLIHVTTLAVTENPEEDLKPYVAQILSKDYLPAPEITNENASATESESVKRENTSSTILYEAYFNIPSCLACAENANFSLPVGVRLVCGPYHELDYDQSIDQAKTVFHEIYPDEEFLPRAPDPEEIIIGEEEPVPDQGDSLQDSNEPVDNASECRELESESTDAQEAKEDAVDKAEECTEQK
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MEISSFSKTVALLVLLLATLTTLSLGQGNRGSGSGTRLGYYRSSCPRAESIVQSAVRSAVQANPTIAPGLLRMFFHDCFVNGSGPNSLLRGFEVIDASKSQLETACPGVISCADIVALAARDSVVLTGGCSWQVRLGRRDGFVSQASDTANLPAFNDPISVQIRKFADKGLNTKDLVTLVGGHTIGTAACALFSYRLYNFNNTNGPDPDINPAFLPQLRALCPNGGDALRRVALDTGSDNSFGNSFYENLRNRRGVIESDAKLWSDRRTQRFVQRYLGERGQTGSRFNAEFGRAMVKMGNIEVKTGTQGEIRRVCTATN
The following text describes a protein:
Function:
Catalyzes the key reaction of chlorophyll catabolism, porphyrin macrocycle cleavage of pheophorbide a (pheide a) to a primary fluorescent catabolite (pFCC). Works in a two-step reaction with red chlorophyll catabolite reductase (RCCR). Creates the intermediate RCC through the opening of the porphyrin macrocycle by the introduction of one atom of molecular oxygen at the alpha-methine bridge. Seems to be specific for pheide a. Belongs to the chlorophyll catabolic enzymes (CCEs).
Subcellular Localization:
Plastid, chloroplast thylakoid membrane.
Sequence:
MSVVLLSSTSATITKSQSKKIPFLSPTTKFPLKVSISPSRSKLFHNPLRVAAPPSVPTSDSTEEKRIEEEYGGDKEEEGSEFKWRDHWYPVSLVEDLDPNVPTPFQLLGRDLVLWFDRNDQKWAAFDDLCPHRLAPLSEGRLDENGHLQCSYHGWSFGGCGSCTRIPQAATSGPEARAVKSPRACAIKFPTMVSQGLLFVWPDENGWDRANSIEPPRLPDDFDKPEFSTVTIQRDLFYGYDTLMENVSDPSHIDFAHHKVTGRRDRAKPLPFKVESSGPWGFQGANDDSPRITAKFVAPCYSMNKIELDAKLPIVGNQKWVIWICSFNIPMAPGKTRSIVCSARNFFQFSVPGPAWWQVVPRWYEHWTSNLVYDGDMIVLQGQEKVFLAKSMESPDYDVNKQYTKLTFTPTQADRFVLAFRNWLRRHGKSQPEWFGSTPSNQPLPSTVLTKRQMLDRFDQHTQVCSSCKGAYNSFQILKKFLVGATVFWAATAGVPSDVQIRLVLAGLSLISAASAYALHEQEKNFVFRDYVHSEIE
The following text describes a protein:
Function:
Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation. Binds to DNA sequences containing the consensus nucleotide core sequence GGA[AT] (By similarity).
Subcellular Localization:
Nucleus.
Domain:
The PNT domain acts as a transcriptional activator.
Sequence:
MLDSVTHSTFLPNTSFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVHPEYWTKRHVWEWLQFCCDQYKLDANCISFCHFNISGLQLCGMTQEEFMEAAGVCGEYLYFILQSIRSQGYSFFNDPDETKATLKDYADSSCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVDRRLVYKFGKNAHGWQEDKL
The following text describes a protein:
Function:
Involved in mitotic spindle assembly.
Subcellular Localization:
Nucleus, nuclear pore complex. Cytoplasm, cytoskeleton, spindle. Note=During mitosis localizes throughout the spindle, is excluded from chromatin, and is enriched on the nuclear envelope remnants that surround the spindle. Present in a ring that surrounds the centrosome in prometaphase and metaphase cells.
Sequence:
MAALSNLKQCPPFSTLPDLALRHNHIPELERYPQINLNSELLANPAGQRYYGGQSFVSVNEGVLKRIARSFFNGGFWKTLEEARSPETREQAPLIAQAGDLIAQFLGLATGLRILPHTQQLSAERIAQFVETRDWLNSDVRYLAWNQHFFCLAVAGVDDVVRIYTKSSSATTATVLKSPSQTQITCMAWRPLCASEIVIGCRQGLCFWEVDSTLHLGRTNAPSEIFKYPNNLPITSMQWNKDGTQLATASIGDRSIIIWQPDTGMMQPLKRLGPPGSLLKWSPDNDWLFAATVDRVFRVWNCHQQWTTERWVCGPGGYVQTACWSPCGRFLLFVSSAEPILYRLQFVQQSLLSSSADEKEILPIADLNACSIDANRTLVGGPAQQLAWDPHGNYLVVTFKATNCIAVFRTFIQKFDLQISAAYYLSGETAAEHPSFICFQPLYEDNDRSVLTIAWSSGRIQYYAFD
The following text describes a protein:
Function:
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
Subcellular Localization:
Nucleus.
Sequence:
MKRQKCFYFNDDDEPKKKKFNADLDSLILDTNPDCIDHTSSPRFRYPTEVGFFSLDSESNFRDDNSSLTYLYGKRLKNKKLNLDLKVGYDTFVGKKENDIQGLGDIFKWISLHPPFNTLTKKGEKLKSLQTDFICWRGLLRKFLCTPYELNENWLIIVRKFKGTHYLVEIKTDEKKQEEREQTTRLKEMSYWGFKFEQYMTTEKPDGKPVTNVPVNNHKQFVSVFLEEKLIAKKIKMTRYKLLKWWSQSILIGVKKIVAGFRDDDGIVREVTKLYTKNIPDQCQSIRNAWNPKVCFNFLDKLLDFIRENVTDENRSYMFEFEPGKKIVKCFHLHQDQAKDGSVTASNTITTTATETSTTVTATTSTAAATTEESANVSTAAATSDTIGNDGACSSNSNNDNNVDENSDDKMNYAKIEVLPQWYRDLFRK
The following text describes a protein:
Function:
Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MNENISVSVRARPFNEKEVKDKEHCLWQFGNNNTITSLPPPITQPVSSLPPISTPIKSSSSSSTSTSAGSLKTPLKTPLKTPLKTPLKTNSTTTNTTVPASPAPTSSLTSKFVSNSYTYDHLFPPTCDNYEVYDTVARELVKSAMEGYNASIMAYGITSSGKTFTMTGSGKKNPGIIPLSIQDIFTYIQECKEREFLLRVSYLEIYNETVNDLLGVNQENFNLKIHEHPVTGVYVAGLKEEIVLSVEHVLSLISAGEAHRHVGSTSYNLQSSRSHTIFKMIIESKEVLPEGSGSGGLESPVRYSTLNLIDLAGSEKASESTISAIRNKEGSYINKSLLTLGTVISKLSEKDTGYIPYRDSKLTRVLQNSLSGNSRVAIICTITLASNNFEESHNTLKFASRAKKISNNAKVNEILDDKALLKQYRNEIAELKSKLSDALSTEKELQETLTEKEKMKITNQELLHKLVDAEKHRSLLESKINNLNKLILVSTSVNNSASKGGSGSGNGNGSRSTFVSPSQNSHHHHGDLGSITPNSFSNLLLQSPSQNNNNNSHISPLSQSTSSLTIGGGSGNGFESNELIQIQSKMAKLELELEEKNKKIDFLTSFNQDSALEKIKQLEGELVQRDMDLGLYQRESTRLQTLLSHKDEKISSLESKLRDILLKFKQIDSENTSLKSKIQEYEVMY
The following text describes a protein:
Function:
Putative odorant or sperm cell receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MYSWYQNSQNQTSNADFILVGLFGETRHSILLYTVVFIFFLMALAGNTLLLILIHVEPRLHTPMYFFISQLSLMDLMYISVTVPKMLMSQVTGDHKISPSGCGIQMFFYLTLAGAESFLLSAMAYDRYVAICRPLHYPLLMNQRVCECLVSGCWFLGMVDGLLLTPITMSFPFCHSRKILSFFCEVPALLKLSCSDISLYKILMYLCCVLMLLIPTMVISSSYALILHLIHRINSTKGHRKAFATCSSHMIVVLLFFGAGIYTYMLPGSYHTVEQDMIVSAFYTIITPVLNPVIYSLHNKDVTGALKSRI
The following text describes a protein:
Function:
Catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate and carbon dioxide with the concomitant reduction of NADP(+).
Sequence:
MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALSEFGDQVFTWQQYDEIVENEGRDAANAAQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASKVVTYDFARLMDGAEEVSTSAFADELIKNLK
The following text describes a protein:
Function:
Serine/threonine protein kinase; part of the subtelomeric hrmA-associated cluster (HAC) containing genes that alter the hyphal surface (such as reduced total chitin or increased beta-glucan exposure) and perturb inter-hyphal interactions within the developing biofilms, resulting in a loss of vertically aligned polarized growing filaments. Consequently, this hypoxia-typic morphotype (called H-MORPH) with altered biofilm architecture leads to increased hypoxia fitness, increased host inflammation, rapid disease progression, and mortality in a murine model of invasive aspergillosis.
Sequence:
MTPFHRLSRFFRQAPSPPRTPITSNFPILDSAVKIEEERMPAFDRGLFYPVKLGDVFRSRYQVLSKLGFGANSTVWFCRDLHQHRYIALKIYIRSSEVNREVQVLKHLSSVKTNHPGSSLVRKMIEEFEITGPSGSHQCIVYEPLLTSLLHFQATLKPQSLPEDLLKGALQQLLLALDYLHSEAHVIHTDDSIFREWDTSEEAEPSPRKVDSSHTIYKSRPFHRKKGWSGFGMPLLSDFGEARLGDVHDGSIQPDIYRAPEVILGMSWTSKVDIWNVGALIWDLFEDHHLFDGRGPNGDHSDAHLLAEMIAMLGPAPLNFLRKAPQSRKYWDSNGRWKGAIEVPQCSLEDSEEYLEGENKKMFMQFVRKMLRWDPEERQSAPELLTDPWLIAQ
The following text describes a protein:
Function:
Acts as a magnesium transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MTTFPTPRLDEVKALIAEQRWLDLREQLSRWPAPEIADLLRELSAAERMLVFRVLPRALAGEVFSYLEHDDQYELLTSLSLEETRLLLANLSPDDRTQLFEELPGQVTQKLLNLLSPHDLKEARQLLGYPEESVGRLMTPDYVAVRPGWTIARALDHIRVRGRDSETIDVIYVTDEKWRLLDAIELRRFILAEPTQTVRSLMDESYVVLSAFDDRERAVEALRRYSLPALPVVDSDGVLVGIVTFDDLIDVAEEEVTEDFYRSAAIEPLRGSYLETPIFELVRKRVPWLVALVFVNVFSGAAIAAFEETIAAVVALVFFLPLLIGSAGNAGSQSATLTVRALATGDIDSGDWWRLLAKELLVALLLGSAMALAVGLLGVIRVGWHVASVVSLTMMVLVLMGSLIGMSLPFLLRRLGLDPATASGPLVTSLSDIGGVLIYFSLATWLLGLTS
The following text describes a protein:
Function:
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. Involved in cell wall biosynthesis.
Miscellaneous:
MISCELLANEOUS: Present with 752 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MYTKEYYWFSQYMIITSTLVLTIIWSILPSSLGEAAPKQFINTLLDIFPQRRWIITLESIMLMGMLCTYIGLLMYNEDTLTPPLDSLSTVTDAGGQLVIEDDPDVFVKKWAFKETSGIYDLSLMDACQLLYLYDNDHTST
The following text describes a protein:
Function:
Transcriptional regulator.
Subcellular Localization:
Nucleus.
Sequence:
MALEESATVVDSLPDFFNSSAATSSSSSLYLNRPFDQTASSSPSDTPPALSRNSSLNALAPAFVPRTSSSLSISPSTSLTDLNQAGKTLVHVYSTPAATFHPVQNHFVYAPQFPVQYLSPFYGGVVEGVAQEMVVGADLDHASKNGGLTEEAVQKIINQVEFYFSDLNLATTDHLIKHMLKDPEGYVPISVVALFKKIKALADSHAQLAQVLRSSTKLVVSDDGMKVKRKIPLTETDLKELQSRIVIAENLPEDHCHQNLMKIFSTVGSVKMIRTCQPQYSSGGASSGSRTAKSDSMMYSNKLHAFVEYESIKLAETAVAELNDEDNWRNGLKVRLLLRHTEKCGQARGKKAGHESEHNFKEDDGFALEVNEKLNEESSHHLDARSNELAEEHDSDGMRKRCGRARGKGQGQGQGRGHGRPQFHQNNCGGSVKSAPSNINRVGLGQPVFDQSAAAKQSSVPRMSDGTKGFSMGRGKPMAIKTT