lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MALQQYNKFPFFFSGILGPTRLNGLQMPPIQTMVRWGHQYAPRSIRNQKAQKGRVPIPIGGSLRGTQLEWGEYGMRLKDRSIRFHAKQLETAEQILKRILKPIKAARVYTRFCCNVPVCVKGNETRMGKGKGAFEYWAARIPIGRVLFEIGGDGMRKELAEHALKQAAFHLPGKYEIIVKQTPKRLGTTLIHETPITTETSKMNYQEITSTTTAV
The following text describes a protein:
Function:
Also acts as a tumor suppressor independently of its role in inflammatory response. Able to suppress overt cell proliferation in enterocytes: restricts stem cell proliferation in the intestinal mucosa in an inflammasome-independent manner, contributing to a decrease in the likelihood of colorectal cancer development. AIM2 suppresses cell proliferation by inhibiting phosphorylation of AKT1 at 'Ser-473', preventing AKT1 activation and AKT-mTOR signaling pathway. Inhibits AKT1 phosphorylation both by inhibiting the activity of PRKDC/DNA-PK kinase and promoting dephosphorylation by PP2A phosphatase. Also acts as a key regulator of regulatory T-cells (Treg) homeostasis by promoting their stability: acts by preventing AKT1 activation. Its role in Treg homeostasis is important to restain autoimmune diseases.
Subcellular Localization:
Inflammasome. Nucleus.
Sequence:
MESKYKEILLLTGLDNITDEELDRFKFFLPDELKVSTAKLENANRTEVANLMIQNVGAVSAVTKTIHVFQKLNYMHVAKSLQEEKEKVDKKYKGKKGTQQVKKRSQTEMSPGASAAPRNSVVEQHIAPEVSPHVKPKQKQMVAKQEPIRKEGLQKGSMTVMVLKATKPFEFETKEGKQEMFHATVATESEFFFVKVFNKKLKDKFTPKNIIIISKYYWHSHFLEVNSVSRVSDAKSDQQISVPKHIIRKAGETPKINKLQTQPHGTIVNGVFVIQKKTERRNHQLFDLSDSTGRMEVLVLGKQNKIECEEGDKLRLTFFELSRTGEKLQLKSGIHSLVKMAFNKNCKTYREILSRDKSIKRTKVSYGIGDGTFRWDIYNRWTTCILRWTISVGKGN
The following text describes a protein:
Function:
Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MYLQIAEIQGDPFSIHPDSSIHSIRAAMEDFGCLVGAFEYDATFDLYLGPPNVYFIAPAEGGVNRPLHYVLICGVGSLDDADDGRPFLQIQNSFGTNWGNGGYGYIAKDLFHHIHGLRGVTLFREEGSCPPLYLVHPQSLCFIRCREALTSKTWMSALDRGCRRCFVALLIIPNDDLNAPINVELFRNELLESPEMDDIVIWARKRTGMPVIRISTEKAAEEFLKKYHTFLIGRFDKFEGPEYVEFVNAAKSDNETQVMRSYQVNRQNFIGYADGAFTLDKIMEFLIYSSPVKHQVFIFANIDDFKNLLDPLQEVARTFKSKIMFIYVDINNENLAKPFLTMFGLEESTNTVVVAFDNGMSSKFLLESKPTRSNIEEFCSKLVQGSLLTYFKSQPIPDNTEAIVQVVVGKTFDEEILNSKKDVVLEVFTPWCFNCEDTSKQVEKLAKHYKSSCNLIFAKIDASANEHPKLQVNDFPTLLLYKANDKTNPIKLSTKSSLKELAASINKHVKVKDQVAKDEL
The following text describes a protein:
Function:
Binds directly to 16S ribosomal RNA.
Sequence:
MANSAQAKKRARQNEKRELHNASQRSAVRTAVKKILKSLQANDSSAAQSAYQHAVQILDKAAGRRIIHPNKAARLKSRLSQKIKNLSSSQ
The following text describes a protein:
Function:
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Subcellular Localization:
Nucleus.
Sequence:
MQSDLGTVHVTNFHGSGALSGDGYNASGSVDGDSEAGTDIRLLAKEFVTQFRIHHEFLYMDMLRSNLSAGLHYVEFQMLHLQQFSGVLFGAVQHNPTRALPLMEHAVWELAQERKLFPAYSRETTIQVQLFWGVPPMALRNLAQAAVAQLVSVSGIVVKSSSTHARCVRAAIQCTSCRSKAYINGGRSIDLPPQCMENSGRGGVGGGGGTSSGKCRPNPYVLLPMECEYEDQQIIKLQELPEDVPTGELPRHLTVVVDRYLVDRISPGSRVQIVGVVSVQEKRGGFDSARGGGRGRAAAGLRAQYLRCVGLMFRTTQDANCAVVSVNQNFSSRVRSRSTMTWQPEEEASFKAFAKQGGVFQKLSASIDPAIFGLEDQKKAIVCLLFGGTRKRIGSNFLRGDMNVLFIGDPSTAKSQLLKFVEKVAPIGIYTSGKGSSAAGLTASVISNGNGDFVLEAGSMVLADGGVVCIDEFDKMREQDQVAIHEAMEQQTISIAKANMTTMLNSRTSVLAAANPTLGSYDPLRSNEDQMDFQSSILSRFDLIFKVIDPRNPETDQRLAHHVISLHKSANGSGGRRGGGRAGASASAGSGAATSAAQSSHGEVVERCFFTKYISYARATCRPVISEEAMKVLLDFYVQVRRDAHQQTLATIGGTSGGNGSAAGGGGSSSNKTPIIQITARQLESLVRITESMARMRLDVLASRSDAEEAIKLFKIATVDAIKSGVADQILTEAQSELVLRVEEALRRRVALGATVEHHRLLSELARMGFDSKLVERALYAMVKREELEWRKQRTLLHRVR
The following text describes a protein:
Function:
Golgi membrane protein involved in vesicular trafficking and spindle migration.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MPGMPPAAPSSPTASAKHKSSYAAAATTSATSTGPVLSYHAHPLNPRSSITISREGSPSPRTSTSALHRPTFVHATTSYAVAAAAGSSAAGSSSASGHGSRGESRGGSAKPYNEDEGYRKEVSAYYPPEFPHSHGPYPYPHHQYTPFSQPDRLDAETSVLDRLRTAVKKMFGGNDNRESKLACLQCSNSEEGGELGRAMMFGWVITTVGFFLAIAFWRGELFRALDKLSHYLAEQGIYGHLTFYVLIFITTIPPLPLYSTFIILSGYTFGVWQGFVVSYLASLSGAIVVFLVSRKMLRDTIVKSLASSSISMSLLHILPTHPHLLLLIRIAPYPYNLLNVILASSPTLTLQTYVGCTAVSLCKLVLHTWIGSGIHDLSESYGHSQSKGQEGSKEGDGADGQWPQDPNGVTGQPAQEGDTQAAKTWTTWAGIVLCIALFFYLMHFAKRAIKKAQAEQAEMEEREREEREGLTAVSARRESEREEMV
The following text describes a protein:
Function:
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
Subcellular Localization:
Nucleus.
Sequence:
MAPSVPRKKRKVSLPKNEEVTARIFEKHRSMAAQQPASLLDHQARALCAAYTGVYAAKEPVRTPGDLARLKGVGGWVVDVMEDSFQGPALICPLREVIHQEKRNTLNKPYVPRLKSAAYAIMITLYMEMERGKEFMMRQELIDAAEASGLSQHAIDPNNSRNSWNDGYSYTGWNSMKTLTNKNLVEKKSNPAKYYLTEKGKETARDCLARSGLDGPAGPLTSAGHPVVVLSDAGSDEYDGSSPLHPDEDPTHNHLIWQWRGAVVWISASKSGKLVLHHCPPTVSRKQDHRNWAVEQEKKMWLASSTVPHRGHILESQAATSRGPKWRRKARRPKSIRVVLTENRGSTAMENSSGNRAGSAEKSLLAMPPHQSNDSFLKAYEVVPRSRRKVVDNIRSQFNIPVEIKHLPVGDALWIARHKELDMEYVLDFIVERKNVDDFLGSIKDNRYKDQKLRLKKCGLRKLIYLVEGDVNTVDGSESVKTATTRYDDTENKYGHLTGSIINYYSMNFSAGADTSRLCLTYDEFVKRCSDLEKVTLSDIFALQLMQVPQVTEEDALAVTSLYPTLLSLAKVYTMLEEMLKNKSGMVNAGASKNIFKLIWAEG
The following text describes a protein:
Function:
As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
Subcellular Localization:
Mitochondrion.
Sequence:
MVILRPFILRLAKTDTTHILSKCLKNRTTNYCTTRTISFSMNKNKKNAEKNNIVVKQEEEIVRIQEKSVDWNRWKHSWKYFNMIMKNKFASAHDHALAARSTKEDQIIYYFRNSGELENWYIMTDEDVGARSWAELVQGPNEMTAAFRGYLNNTPPKDYVISNDPLEPTPNFYGFAYVETKPFEGVLGREQFMNFQGFNAFKIRLRGDGRKYHFETLCDFGFGDRMMYTAPIYTNGGPLWQEVTIPFAKLIASIDSGAVAKQREMALDRMSNFRFLIRDKIEGPFHLEIDYIAFTRDVTYEVCESGIDYYDPWEPINSNSGM
The following text describes a protein:
Function:
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MCQSECDHLELTVVERQRIREMLHRPPVLLVIGMAGAGKTTFIQRLAAELNQHQAAYALKPRIRQDIVSKVPYIVNLDPAVLDTPYIPSVDIRDTFNIGDLMKKHHWGPNGAIMATLNLFATKIDELDNLMRKKAERTSCYVVDTPGQIEVFTWSSSGEIVSKFFGSAYPTILLYIVDSERCLNPITFVASMLYCCSIMERLELPVIIVFNKSDLIAPSLSVEPDTFNRWAPWVYMRNNVALSEAFSDFQERNVNSIAYSDIFYESLSTILEEFYNVIDYVNVSSYTGLGFEGLLDKIRRVSAQYIEEYPTRLDEHRRAVEQEKQQKEREKEDPYQSLFADMSLLPTRYVCGDDGVEVLEDSANLDGVD
The following text describes a protein:
Function:
Functions in nuclear protein import.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNTIGNCNTMVNPAARLNRFKNKGKDSTEMRCHRIEVNVELGKAKNDQMLKRRNVSLFPDDATCPLQKKHNNQGTVNWSVDDIVKSINSNNLQATQSCQETTFSGKQPHNLMWAGLIPKFVSFLGRTDCSPIQFESAWMLTNIVVVDGGAILAFVSLLASPHAHISEQVVSVPENIAVFRDLVTKYSAVDPLLALLAVPDMSSLACGYLCNLTWTLSNLCFRLLHHDDPKVLADTCWAISYLTDGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDERTQVVIDAEALAVFPTLLTNPKTNTWKEAMWTMSNITAGRQDQIQQVVNHGLVLFLANTQKEAVWAVTNYTSGETVEQIVYLIHCGIIEPVILVILDAISSIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENDLIKYFSVEEEEDENMVPETTSEGYTFQVQDGTPGNFNL
The following text describes a protein:
Function:
Participates in both transcription termination and antitermination.
Subcellular Localization:
Cytoplasm.
Sequence:
MIKGTGHMIVNIANDRGMSIDSIRKTIKESVLIAYKKYFGSNENAFIKFDDDTGDLSVYAKKKIVKEVKDSLLEILEKDISKENIVEGDYAYIEINPKVFDRLSIQVAKQRTKNDLQGIEDNEILSEFKSKLNKVVIGYVQQNRNGDLYVNLGNTDGIIPKKYQSPREVYNLNDKIRVLVYNVKKGKNGIEVILSRTHPKFIEELLALEIPEIEEGIIKIHKIVRDPGYRIKVAVYSEKEEIDPVGPCIGQKGVRIQSIIKELEGEKIDIIPYSKDIKEFIKDSLTPSKIEHVYILDEDLHKALVVVSDDQLSLAIGKMGQNVRLANRLLDWAIDVKTSSQFAEMKANSEFKQETLEMFDKVMQDVVEEEQFEEISKISDLKLLDPSVISNLSKEGFDDINNFLQADEGVLFNLGVSYEKQEEINKILKEGMIIIANDNDESMEKVEEDEELLCPECGVVINENMTSCPGCKIGLSFEFEEE
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
Miscellaneous:
MISCELLANEOUS: Present with 861 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm.
Domain:
C-terminal extension may function as a nuclear localization signal (NLS).
Sequence:
MSKIQVAHSSRLANLIDYKLRVLTQDGRVYIGQLMAFDKHMNLVLNECIEERVPKTQLDKLRPRKDSKDGTTLNIKVEKRVLGLTILRGEQILSTVVEDKPLLSKKERLVRDKKEKKQAQKQTKLRKEKEKKPGKIAKPNTANAKHTSSNSREIAQPSSSRYNGGNDNIGANRSRFNNEAPPQTRKFQPPPGFKRK
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MKTNWVSASGLAAVLGVAGLVLALIKDPKSWNLKLSVLPSWLELNQRENNNRPKKLFLLPGLQNLGNNCFLNVILQALGSCSNFQSFLQKVIEEWESFAGEEWNESLQLTVALAALLEELSVISRESIVLSPRKVMLAMAHYIQNFNLTSQQDAEEAFLHLLSSLRDEFSDSYLPKHHSLADAFASPNCRILTPNRIEIQSEQERWQQHFLGPFDGILSSILTCQSCSTEISLNFQFFHSLPLLPVLEGGATIRVGCRLEDCLRQFTVSEQVENYSCSHCWHIAAIKYLSLRGATETEIKRLKSCNEQDSCTCHLLVHLENLPWSNNFSRTLKQLSIARSPKILCIQLQRASINFFGEVVKLQGHISFPLTLNLLPFMMKEMQCQKPSSHLNHLDVQYDTRMLNSIYERNASKLLSANAFRSPAHAEAFLGQSKIPQTTDIFSSQANEKVSAACELVPSIPQVYRLVSVVEHFGRACGGHYTVYRSLQSESHEEHPDENCKPSLMHWFCISDSNVYRVSEEDVLAAEASLLFYERIVES
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MVGLSPTPSLKLIITHFTQHGTYSNPNWRWMMLPKVWRFVGFASSVVGLLCYALSSSFNYLFGEWNLLKIFLYSAFSFIICLVILIYIQRNCNIIEVSDLKLIRHFWKTQCGFEIDLLYFFLGSLIVQLMKIKLQLFILGAWSSQYISELQDGNSVILYVDSLQSPSVNNNTSSSATNSIDSPQLVINTNNGSMMEQLRTCVKALKHDNLNLIQIISEHVKKYVEEHSQLVVTYPNLIMDALKPETMNDLEEIAKVMMMIIRLTKLNIEDVHNMSWKDLEDEIERWIRTFNVESTIKLLNFVDYVSSHSSGIHSPERLFKILEVFETLCDLIPELASLFCDQYNLSLRSEATAIWNRLGKTIRDIFKELEYLICRDLTKVTNFGGVCRTEQTLEQVFYDSSLSSKIRRIMDTLESNLEAKSKCYEDPSLGYISESILQDASERLKFAAKTEVKNISPNLADTIGRMWVSRLGN
The following text describes a protein:
Function:
Transcription factor that plays a role downstream of the MCK1-MKK2-MPS1 cascade. Required for hyphal morphogenesis and pathogenicity. Is an important oxidative stress response regulator and plays a positive role in the regulation of extracellular peroxidases.
Sequence:
MPDVKHESSTPGMSPELYTAVYSGIQVFEMMANDVAVMRRRTDSSLNATQILKVAGVEKSKRTKILEKEILTGAHEKVQGGYGKYQGTWIPYERGVDLCRQYSVYDVLQPLLAFDPAQVGDYTPTKEQAMAARRKRIVATKQQSRMDMPLAQPLQLPQTHTPLSVSAERALSMLGNNSMSNMSGSPSMSNMGTPQIGTPGTDSASPPAKRFKSETNGHGHGGPQNQGPQGHQSTPGHMVQQQQQQQQQQQQPNHTLEFDENLPTADLFSPTNLPMDPLPPDAHNDASRDIMTQLFMGNGATSFSPAINVDVPIDDMGHAALHWAAALARVDVVRALVMHGADRRRANYAGETALVRAILVTNNFDSGTFPQMLDIIYPAIPLLDKQNRTLLHHIALTAGIRGRAAAAKYYLECLLEWIVRRGTSPKRIRFSLARFMQEIVNAQDKYGDTALNIAARVGNRAIVTQLIEVGADPMIPNRAGLRPVDFGVTINLAEVKPMLSRSGERVGFSANAETRSKDILQTIISSIEGLDTDFSSEMAGRTRAAEQAHAELRGATNALSEARQRLEHLKNLSSKRDAMLKRATNLERALHDEDAKFQAHSGGANMSFEGNFDADQPFRTRALFQAPRDKEWSVQEMNSIEVPSQQVLQARVRAYRKNQAELERTSGELRGRSTELEHKFRRVIALSTGVAEDKVDELLEGLVQAVESDSGEVDINRVAGFLRKLEPPQQA
The following text describes a protein:
Function:
Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MYCAHPELTLWRGLQSPVYFLRTVLHEIKYCADICASVWLTVKPSLQVFRARFSEITPRAVQLACETLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPESFHKIKVTHEHEDCLVEFNWKRHRLFNHTEPTATVVEVGSKPKSKWRPQPLDTVELEKLASRKLKINAKETMRIAEKLYTHGYISYPRTETNIFPKDLNLVHWGDFAQRILDRGGPTPRNGNKSDQAHPPIQPPPNTPGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAHERFIAHGLMILARNYLEVYPYDRWSDKVIPIYEKGFRFQPTTVEMVEGETSPPQLLTEADLISLMEKHGIGTDATHAEHIETIKSRMYVGLTADKRFLPGHLGMGLVEGYDAMGYEMSKPNLRAELEADLKLICEGKKDKFVVLTQQVQKYRQVFIEAAAKANKLDEALSQYFGEAAEVSQQEEIYPAMPVPIRKCPQCNKDMVLKTKKNGGFYLGCLGYPACKAAVWFPDSVLEVSKDDSVCPDCVPHPVYKLKFKFKRGSIPPTMPLEFVGCIGGCDETLREILDLRYFQGPPRALHPASHVQLNQSLNRMGSRYNHQPRPPPEGRNRPPNPSSGTHLSFPAAAEGSNSVMCNCGQEALLLTVRKDGPNQGRQFYKCGAGACNFFLWADQQAEGGASAERRTAVIPAPPPAGGSREGYGSSGGGGDSGGAVCMCNQPAITRVVQKDGPNKGREFHTCQKPREQQCGFFQWADENMAPGENGWEIRKGIA
The following text describes a protein:
Function:
Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (efbA).
Sequence:
MTEIIKNTKYLDYTSDSVEFYPFNNNIFVCGTYEIEKGDTEYKERRKGKLYLFEIEEEQQQKENDNNNENNNNNKLFKEIQNINFNSGILDMKWNNNKDRILGVVMSKGELNIYQYDEVEKKLELKSSTEISLSNDILSLSLDWNKSGDKLICSFSDGNIGLFKVTKDYSKVTEEKRWKAHDYEAWICAFNYHDESIVFSGGDDCKFKIWDLNQLLNHNDDDIGIPPTPKFTKRCDMGVTSIHCHPTIENLIAVGSYDECLRIWDLKSLKQPIITTDSLGGGIWRIKWHPFQKNKLVTACMGGGFHILSTDPENINDFSTLQIEQSYNGPHKSIAYGVDWSFNKNNFDKQFIGCCSFYDKCLSIWIP
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MDAGVAVKADVAVKMKRERPFKGIRMRKWGKWVAEIREPNKRSRLWLGSYSTPEAAARAYDTAVFYLRGPTATLNFPELLPCTSAEDMSAATIRKKATEVGAQVDAIGATVVQNNKRRRVFSQKRDFGGGLLELVDLNKLPDPENLDDDLVGK
The following text describes a protein:
Function:
GTPase involved in pre-60S ribosomal subunit maturation.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MVKKKERSVNVSGKPKHSLDVNRDAGNKNKSGGTARTAATVRRLKMYKTRPKRDSKGTILKHELQSKELPSTRIQPDRRWFGNTRVVNQKELEFFREELQSRLSSNYNVIMKERKLPMSLLNDHQKQARVHLLDTEPFADAFGPKGKRKRPKLAVSDYESLAKRADGSQDAFEEKHGDDPVDPNADGFRDLVRHTMFEKGQSKRIWGELYKVIDSSDVVIQVLDARDPQGTRCHHLEKHLKEHCKHKHMILLLNKCDLTPPWVTKGWLRVLSREYPTLAFHASINKSYGKNSLLSVLRQFSRLKSDKQAISVGFVGYPNVGKSSVCKVAPIPGETKVWQYITLTKKIFLIDCPGVVYGSSDTETDIVLKGVVSFLIRFIIPLNPRI
The following text describes a protein:
Function:
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
Subcellular Localization:
Nucleus.
Domain:
The coiled-coil motif forms a homodimeric contact and facilitates RIX1 complex oligomerization.
Sequence:
MDEQVIFTTNTSGTIASVHSFEQINLRQCSTQSRNSCVQVGNKYLFIAQAQKALINVYNLSGSFKRESVEQRLPLPEILKCLEVVENDGVQYDRIQGVNHNLPDFNLPYLLLGSTESGKLYIWELNSGILLNVKPMAHYQSITKIKSILNGKYIITSGNDSRVIIWQTVDLVSASNDDPKPLCILHDHTLPVTDFQVSSSQGKFLSCTDTKLFTVSQDATIRCYDLSLIGSKKKQKANENDVSIGKTPVLLATFTTPYSIKSIVLDPADRACYIGTAEGCFSLNLFYKLKGNAIVNLLQSAGVNTVQKGRVFSLVQRNSLTGGENEDLDALYAMGQLVCENVLNSNVSCLEISMDGTLLLIGDTEGKVSIAEIYSKQIIRTIQTLTTSQDSVGEVTNLLTNPYRLERGNLLFEGESKGKQPSNNNGHNFMKIPNLQRVIFDGKNKGHLHDIWYQIGEPEAETDPNLALPLNDFNAYLEQVKTQESIFSHIGKVSSNVKVIDNKIDATSSLDSNAAKDEEITELKTNIEALTHAYKELRDMHEKLYEEHQQMLDKQ
The following text describes a protein:
Function:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Subcellular Localization:
Cytoplasm.
Sequence:
MAVERTLIIVKPDAMEKGALGKILDRFIQEGFQIKALKMFRFTPEKAGEFYYVHRERPFFQELVEFMSSGPVVAAVLEGEDAIKRVREIIGPTDSEEARKVAPNSIRAQFGTDKGKNAIHASDSPESAQYEICFIFSGLEIV
The following text describes a protein:
Function:
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSHATLTPAPKNRSSLRAATLPKWFPWAVAAGSVLLGLGISTAAGLNSSIQWALIAAVLFVGGSYGISARVEGGRQAKDRVATSMVWVAFLLALIPLLSLIWETVKQGVKVLDGYFLTHSMGVVGDSEPGGGIYHAILGTLEQVGLATLFSVPVGVLTAIYLVEYGRGRLAKAVTFFVDVMTGIPSIVAGLFVLSLWVLILDMGPSGVAGSFALCILMIPVVVRSTEEMLKLVPNELREASLALGVPKWRTILKVVLPTSIGGIVTGVMLAVARITGETAPVLLLVWGTDFINANPFQDPQESLPMYIYLQYGAGSDAAYDRAWAAALTLIAFIMILNLAARGVARWKAPKTGR
The following text describes a protein:
Function:
Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips. As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes.
Subcellular Localization:
Nucleus envelope. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side. Note=Targeted to the nuclear envelope (NE) during interphase. Associated to the cell plate during cytokinesis in root tips.
Domain:
The KASH domain, which contains a transmembrane domain, mediates the nuclear envelope targeting and is involved in the binding to the SUN proteins.
Sequence:
MDLESESSVLESVEDNNGLIGDLDKELNSPVETSPLISKGFGLRKWKRRLRRDLVKDDTSVSMENSKALKRVLSGLVDPNAKQMHLPGPEVRQDSVGSVGSVNSVVGFVMGGESYGNGLAFAAGVDSDNSEDRSSTMSHSWDKHRGKVSGGKSVISSGDSSQQRKSSVEKSNKLRGERIKIEKENSHSSMESADSRSSNFVFMQGASYSLSSREQGGRRMMDYDDENSDHDAHTSKRKDNVEEEEEETEDYSQGDCVEESQIKSNGSSDNLDPLIVAVNSFQTLQEALQKELQKFQELGKEEPITSLHDGGESSSCIHAGHEGASEASSSYRFGSEKMGEMELTSLDSEILNLVNNVEHLEIKLEEAKRILEVKETQIRELESTINVSETCNGGTEIGIEDIFQQKVEAEIEYIIFSRSVGNLKRRIKLIEEEKTLGLSKLDKAETKAENLKNQAQDLQNHCVEITEIQEVECLKKRAFKTTRCLLLQLGLLFILYYSLLPEPEIAVPT
The following text describes a protein:
Function:
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
Sequence:
MGYHRNRRGRGSSSSSSSSSRRTKQEASCDDAPGTSLPRQEDNAEEESNSPKIQLAMWDFGQCDAKRCTGRKLSRFGLLKELRVTNGFGGVVLSPVGTHCVSKEDHPIVQRKGLAVVDCSWARLDDVPFVKLRCGAPRLLPWLVAANPVNYGRPCQLSCVEALSAALIICGEEETGELLLAKFKWGHSFLSLNRDLLKAYSKCENGTEIINVQNSWLASASSVPKSPVNVADKSHAGSDSESDDGLPPLEENMNHLDLSGDEESEEESEIENEDTK
The following text describes a protein:
Function:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MSKQRGTAAYRGFTVSHQRVVLDLSFNGTLVGFTELTIIPTHRGLRTIHLNCRQASVQSATVNNHPADFSYSDHLTGATISETRDVHRYPELKRRIYAAASDGVHGELSILIPPDVHVQTQRAGSRDPSIAPDDAPTPGGTSTTELAPISVRVNYYLKNPTDGLQFMRPTADAPYRVPHLYTITSSPDAARTWVPCVDSLWERCTWEFELIVPKSLHIAEDEEEAAANQSANLPIEQAPTTNVDTSDPDSQVVVVCTGDLMEQVTHPNNPSKTIFCYTQAVPTSVQHIGFAAGPFHIMRIEATNRHGGQVTTGIVTEVSAGASAVVDDSGQPEILAFCLPGREDELRNSISFTRQALDFFSQQYGSYPFGAFRMVFVDEPPQDCTTQSMIAVCSNDLLHPTSVIDQAIENRQILSHAIAFQWVGINIIQATWADTWLVNGLGLYINGLFLRRLMGNNEYRFRLKKDLDRLCAWDIGMPPLYEAGAFEPPDAATLPFVNLKAPLVLHILDRRLRKMGASVGLGRVIPKVFLQAMTGEMTNNMLSTQLFLRTCRKVSGADLRLFTEHWIRGSGCPRFICSANFNRKKLLIEMNIRQEVPAAQFAAARPGDALAANAVPLFEGQMTVRIHEADGTPYEHVLEIKGPAKRYEVPFNTKYKRVRRNTKRFQARQAAAAAAAQGDQEAQEAIGLIDLGFGLGMWEDEKAREEWKVADWTEEDEEKMSSAPYEWIRMDADFEWLASIHFEQPDYMWVSQLQRDRDVVAQVSAVHALAQMPSLVTCSMLTRTVLVNKYFYRVRTEAVHALVHCAIPQLDNLGLFHLLKLFRTQFCHDPPDEASIENPLDVPCIPRANDFSDAADYFLQRALIHAISRVRNPDGRTPPQVKRFLINLLRYNDNSTNHFVDDFYLAGAINALASAFIPIESAVAATQDADMASEESFLLAHAVAEVERLQELDRLVPSYHNVITLASLDFQVAMMLANLKPKDLQLFFTYTRQGNFTPVRIAALNCLLLVGNLDHRVIARYCFALLRLDENRTVKRALARAMCEGLAVAMSTGMFGGGGLRGPEALLIEEDSGHVNAAEKARDAQLEAMLKTLKKEIGRSAGVREGFLSALLAPSVDVEARWALLKLAELLFRPAEEKELPLQHKVQLRVRMPSTPNTIDAAPLESSSISKIKLVRPSTATGGDEAVPTTPSATATNAPRVAFETPEKPPASASDKKKLKPKKAKPLAPGQASGMSFADLTACRNTLKKLMQNKFAAIFLNPVDPVRDQATNYFDIIKEPMDLGSILNKLDSGQYKDRHELRADFELMISNAKTYTPDAKAWAHKQAVGLEKVFVPLWNRMEKTLEQSAARQKAAQDAALANEQVGGVSNSPERPSPAKLDASAAAAATAPASVGKVGNGIGREASTPSPAAPKLSLKFKLKTKLAGEESPAPMSTPTPKPRAPVVETSAAPASPPSIKLKKPLIKLKKGNHDDAAAPEVRTPPPPLAAKSSEGLAQSVDDDILEALGEVPKASKAKPNKVTSNLSKVAASASPVPGPTASPSSNKKSRVVASHATGAVISNDVATGSTLAASPSKDIAKWAEADPIGATAAMAVNSKKCKVLLQVLKKAPSSIFFRFPVDPIRDGLPTYLDEIQQPMDLSTMEKKVNQGAYTTMGEFASDMELIFANCRQFNPPGTEPCQHADELERLWRKEWAKAVTPRLEANEKRALVGLMNRLKTHQSSLLFREPVDPVALGIPTYFDVIAKKDARDLSLIEAKLKGDKYDSFAALDADVKLMLRNCYTFNAADEAIVGIAKGFETYYKRELAHAKQQAGVSGSGEGSAGGAKRKLPANGTAANGSKKVKSG
The following text describes a protein:
Function:
Transcription factor. Required to activate programmed cell death in the sister cells of the serotoninergic neurosecretory motor (NSM) neurons. Negatively regulates the activity of ces-1 which in turn negatively regulates the activities of cell-killing genes. Binds to the DNA sequence 5'-RTTACGTAAY-3'. Involved in the development of the excretory duct cell, by positively modulating embryonic transcription of putative transcription factor lin-48, acting in concert with NFIL3 transcription factor homolog atf-2. Positively modulates expression of neuropeptide pigment dispersing factor homologs pdf-1 and pdf-2.
Subcellular Localization:
Nucleus.
Sequence:
MDFHRALSALFTNQAAVQPLLGSLGFPFNDGTSILTTALAAQSGGKKLDTPLGILPFDSLPTTNLLTPTKKIKLEDELCASPVSSRSSTVSSSHFSSPQRSPSRKMSVPIPEEKKDSAYFERRRKNNDAAKRSRDARRQKEEQIASKAHALERENMQLRGKVSSLEQEAAQLRFLLFSKISPANSEVSCESNDSTETNDSNDSKSDSTIEV
The following text describes a protein:
Function:
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Subunit of the 40S ribosomal complex.
Sequence:
MAEEGIAAGGVMDANTALQEVLKTALIHDGLARGIWEAAKALDKRQAHLCVLASNYDEPMYVKLVEALCAEHQVNLIKVDDNKKLGEWVGLCKIDRKGKPRKVVGCSCVVVKDYGKESQAKDVIKEYFKCKK
The following text describes a protein:
Function:
Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.
Sequence:
MSLGKKVTLNSGAQIPQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYKDVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPKSKARTVGVSNHMIPHLEAIINATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAFGNNGFGVPLLVTRPEVKEVAESASKRLGTTVTPAQVILAWSQVGGHSVIPKSVTPSRIHENFKEVELTPEEIAKVSELGKDRRRYNTPYVANTPRWDIDIFGEEEEKPAGHKIWSPVLFAAGYSSSAWVGRGKVSWDTVHLVGNHTPLLRQQTTPRFARLSF
The following text describes a protein:
Function:
Probable transcription factor that plays a role in the development of the dopaminergic neurons of the male-specific genital sensilla (simple sense organs) known as rays, by negatively regulating the activity of the transcription factor ast-1. Involved in male mating behavior, probably as a result of a role in the differentiation of male-specific diagonal muscles. Required for development of the male proctodeum. May be dispensable in hermaphrodites.
Subcellular Localization:
Nucleus.
Sequence:
MPKEQYMCQLCANHGIFNQPKKGHKQKCPYRTCPCSLCALNTKRRALDQIERQLKHTNEPMTGQTATSMASPTPECPLSPTTPKMTPHTPTSGKDTFRNSISSSNMAFTVQLPATITKKELKLLRRDDTPLQNSLERPFPRSIDEAIETIKKEKMSSIFHSAEMLAVGESATSLI