lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
S-bacillithiolation is the formation of mixed disulfide bonds between protein thiols and the general thiol reductant bacillithiol (BSH) under oxidative stress. BSH is an equivalent of glutathione (GSH) in Firmicutes. This protein is a NADPH-dependent bacilliredoxin reductase, which debacillithiolates (removes BSH) the S-bacillithiolated BrxB (BrxB-SSB), and to a lesser extent BrxC (BrxC-SSB). Involved in a redox cascade increasing the efficacy of BrxB function by reducing BrxB-SSB and thus reactivating it. Has NADPH-dependent oxidase activity under aerobic conditions producing hydrogen peroxide (H(2)O(2)).
Sequence:
MIQEKAIIIGGGPCGLSAAIHLKQIGIDALVIEKGNVVNSIYNYPTHQTFFSSSEKLEIGDVAFITENRKPVRIQALSYYREVVKRKNIRVNAFEMVRKVTKTQNNTFVIETSKETYTTPYCIIATGYYDHPNYMGVPGEDLPKVFHYFKEGHPYFDKDVVVIGGKNSSVDAALELVKSGARVTVLYRGNEYSPSIKPWILPEFEALVRNGTIRMEFGACVEKITENEVVFRSGEKELITIKNDFVFAMTGYHPDHQFLEKIGVEIDKETGRPFFNEETMETNVEGVFIAGVIAAGNNANEIFIENGRFHGGHIAAEIAKRENH
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MEHQHTSGAQNLNIYSRIIQLKERKSVIEIAKKYNHFITYFITFTKLFIFFFGSLFSLFCLGFHPLKWKYICTTKQSLEFISRKLGFFLGGYSRCTFCIATIISFFIFPSVEMPGRQPMTTTTYEGEQHIIAAAQHILKLLGENKNLTGDFRRALTELDSHLSAMTIINESKRWGFAEVEEQLKCAERKVMRWESNPSLIWDSGPAEASEYIQAVNEIHTVMETLGGLPMNDHGRPKELAFRAQCVQQIAMSRLEEELYHILVQHKQSFESKNIYFPPSVDFFYDESFVSVEDEIVEDTSQRDNSGRESTEYTVDLIDPLVIPDIKSIASVMFASGYDREFCEAFIGNRKEALDEHLSNLEIQKLSIDDVLKLEWDTLSCEIKKWVRAVKIIIRVYLASEKRFCNQILGDFGSLDSYCFVEISRASVLYLLSFGEAIAMGPYNPEKLFRFLDMYEVLADLHLDMEALFSEVANSYVTSEFHDLLRRLGESASTTFFKFGNAIALDASIHPFRRGEIHPLTRYVMNYIKTLTAYCDTLNLLLNDQDVDDPNPVLETDNGQDICTSTFSPMGCHLRSITSTLESNLICKSKLYKDGSLGHIFLMNNIHYMVQKVKGSELRLFFGDEWIRKHNGKFQQHATSYERATWSAVVSLLRDDGRTSLKERCRRFSNAFDDVYKIQTQWRVPDLHLREDLQISTSQKVIPAYRAFLGMNDKNGSDKYIKYTSDDMEKMLLDLFVGSPRSLRNSHRW
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Master regulator of basal/root fate. Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis. Modulates the root polar auxin transport by regulating the distribution of PIN genes. Essential role in respecifying pattern and polarity in damaged roots. Direct target of the transcriptional corepressor TPL. Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs).
Subcellular Localization:
Nucleus.
Sequence:
MNSNNWLGFPLSPNNSSLPPHEYNLGLVSDHMDNPFQTQEWNMINPHGGGGDEGGEVPKVADFLGVSKPDENQSNHLVAYNDSDYYFHTNSLMPSVQSNDVVVAACDSNTPNNSSYHELQESAHNLQSLTLSMGTTAGNNVVDKASPSETTGDNASGGALAVVETATPRRALDTFGQRTSIYRGVTRHRWTGRYEAHLWDNSCRREGQSRKGRQVYLGGYDKEDKAARSYDLAALKYWGPSTTTNFPITNYEKEVEEMKHMTRQEFVAAIRRKSSGFSRGASMYRGVTRHHQHGRWQARIGRVAGNKDLYLGTFSTEEEAAEAYDIAAIKFRGLNAVTNFEINRYDVKAILESSTLPIGGGAAKRLKEAQALESSRKREAEMIALGSSFQYGGGSSTGSGSTSSRLQLQPYPLSIQQPLEPFLSLQNNDISHYNNNNAHDSSSFNHHSYIQTQLHLHQQTNNYLQQQSSQNSQQLYNAYLHSNPALLHGLVSTSIVDNNNNNGGSSGSYNTAAFLGNHGIGIGSSSTVGSTEEFPTVKTDYDMPSSDGTGGYSGWTSESVQGSNPGGVFTMWNE
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex is non essential and only mediates the import of few proteins under precise conditions while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins. Strictly required for import of TIM23 in some conditions, when a low membrane potential exists in the mitochondria.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Mitochondrion intermembrane space.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIM13 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane.
Sequence:
MGLSSIFGGGAPSQQKEAATTAKTTPNPIAKELKNQIAQELAVANATELVNKISENCFEKCLTSPYATRNDACIDQCLAKYMRSWNVISKAYISRIQNASASGEI
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MEEHKSVISTCEQDQHVVAAAQHILKALAASKNVSDDLRKTLLDIETQLSSISIVNERKGREIKHLERQLKCVEDKVMRWEANPSNESSEYLKVVGEIQVLIQNLESFSVNEKWKQKELVRRANEILQVAMSRLEKELVHILLQHKQHLEPEYLYFHFNRVDMVFDESFRSVEDEQIDEASRSSGASQSEASTVDLVNPAVLERLKSIASVMFASKYHQEFCQVFVTSRRDALAEYFVILEMEKLRIEDVLKLEWHCLNHEIRKWVRAMKIIVRVYLVSEKRLCKQVLGDFGSFYQCCFSEISQSFMLHLLNFGEAVAMGMHTPEKMFRLLDMYEVLEKLDVDVDVLFFEEVGSFVRGEFHKLLRSFGDTIKSTLLAFRNAIASNHSKTPFPQGGVHHVTKYVMNYIMALVEYGDTLNLLLVDDTSIDPAGNKDDTPCLSLCPVACQFRSITATLESNLSNKSKLYKDEALQHIFMMNNIHYMVQKVKCSDLSHFFGDCWLRQHIAMYQRDARCYERISWGSVLSMLKEGSVSNCVSQRTLEKRCKEFSTAFGEVYRIQTGWFILDPRLREDLQISVSQKLVLAYRTYIGRNSSSIAEKYVKYTEDDLQSYILDLFQGSPKSLHYPQHRK
The following text describes a protein:
Function:
Involved in the lipid remodeling steps of GPI-anchor maturation.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MCSRARFGLRLASVCISVEGCRFFAKGSSCLPASPSPTRPAMIRYRVVALVLIVLLIYFFRLIFASGGDRSQFYQNCLKFCTLDNCTQSGVSYKKELQWKHDPINKLLLWTCYDECGYDCMWRTTAAFHNRNWTTPQFYGKWPFVRFLGMQEPASVLFSVANFATHYKMLQRFRREVRTDSPMYGTWRAFSYICLNAWIWSAFFHTRDFPVTELLDYTFAYSMVLASFHCMVMRMIHRSSIVVRGAFSCLCVLFFVNHFSYLSVGRFDYSYNMKANIVTGMSGALGWILWCFLQRKKRRYVWKCFTFIVLATSSLLLEINDFPPILWTFDAHSIWHLVTAPLTILFYSFIIEDCKTLRKELVGVEDEESRKLL
The following text describes a protein:
Function:
Mediates down-regulation of protein synthesis in response to stress conditions by the phosphorylation of the alpha subunit of eIF-2 (tif211) on 'Ser-52'. Protein synthesis is inhibited at the level of initiation. Activity is inhibited in the presence of heme.
Sequence:
MLGTSTKCSKRDCNYAKENISRIMPTIGLGYKQNFEKKTADTQSSCKLLLVALLESFCKHSDQTPEQSKQMFLYVAHSLQNSGIIDFEFSEELEPIRNAYADSLHNLLSKAFRSTLPMSSTKDSKKSRYSSPDGVLAKTASFLSVLSDGGYEDDVMNVKPSVNVLSNRLNHLPVEALESCFPQTTLESSTFADFCEHKDGTGNLSFSNFDSFPTVQRSRYASDFEELELLGKGGYGSVYKARNKFDGVEYALKKIPLRLRSFSTSSNIFRESRTLARLNHPNVIRFFSSWVELLPSSEKQIEEEPLASADETLSQSADIDNFMFDMDTGLLQHTYPSSVQILFQEDSVADDLTPCYSTKNSTCNLTDLFKKEADQDYAESHDCSSTTSQVDTLGKLAPTKSASEMLLMDSFLSEREEDECSNIPSFDQQPLCLYIQMALCEETLEKHINRRNKHIHGVMSKGLRNCYILLFARILEGVLYLHDAMHLVHRDLKPRNIFLSSGVHSEPCSVCLPNFSDEDNVEVSNAYEPVNQRTLCVVPKIGDFGLVLSQSDNLEEGTNSSAESSFVGTSTYAAPELFSKHMRSVMNNNSSTDIYALGILFFELLYPFNTRMERASAIANLKKGIFPHDFLDSMPEEASLIRSMLSSSNKRPTAAQLLTSNLFHDLVVNELHVYQALLEDAEKRNNNLKAELNILRVLNPNYDC
The following text describes a protein:
Function:
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MKISLKNLGYEYPTFENNKNGIYDVSLEIDSHKRIAIVGHTGSGKSTLLKLIKGLLKKQTGEININGKIEDIGYIFQYPEHQIFETTIFKDISYGLKRLKLNEKEVLERVEKILELVGLDKDCLHHSTLNLSGGEKRRVALAGVLIMQPQLLLLDEATVGLDLNGKEQLFKILLDWQKEENKSFLFITHDMNDVSEYAEEVIVMDKGKLLYHTNPSELFEKYSDELESLGLELPECISFFNKLNQKLKNPIKISGDIKEESILKVIEEKIK
The following text describes a protein:
Function:
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis.
Subcellular Localization:
Nucleus.
Sequence:
MGDGHAAPNQGFDGYREYFVGKQRLQKAQEEQLRGVCGARTPIFRGCRVHVNGHTDPDREELRREIVMHGGTFVHYLARPSDVTHIVAEHVPVAKRRLWHACKVVRPAWVSACLCSGELVPWKPYAAAGTEAAATIMASVGSPQGPRLTCKDPGFIEDFFAKSRLHHLSAWKAALRERFLDRHLRMNEGALNDLRAPPAHVLHVDFDCFFATISGIKAGYPSKAEVPLAVCHGGSSSDVASCNYAARECGIQNGMWVSKAKNLCPQLVCLPYTYDEYETISNAFYEVLEGLKAFDAVYPISVDEAVCVIDMPLDTLSCQNLCIRIRSEVAERTGGCSVSVGCAPSLVLARLALKRAKPDGYLVCTKESIKGGDTQVVSPAHLFETCALRDLPGVGRAIAEKLLLGSTGHEHTIAQVSQLFSRSELIARLGSITGAKLADLFQGLDDVESSRMLCNPRAYFARKSLSVEINWGIRFDAVPEVDAFLDRLVQYLVGKLNELRMTTSHIVLKIARRSRDAPIEPPKYLGMGDCDSYSKSCRLGLATNIPGVISAEIKAAFRMLCCPAKELRGIAVQFLKLKEASISQMPRQLRFPFGTIRPLTTPKNRITASVTELPPVVYKRATPIKDFFDRHKRTSSSPSPDFTHMMSASALCESFLGGLPTDLAEEIRREHRIYQKARRSYLQSSRKRIGAGAHGNKSDHALKNLGILEPVTFQNLISQEKIKSLVREWISQTLRSDGPNHKDLDLFTNYLDRLISGGPRRLPTLLSMARLISDQLRIHEAQGDRPSFQEWEEYLVRVVLVRLNRCKQLYTQNVEILFDIYPQIDRP
The following text describes a protein:
Function:
Also has a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released; Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors.
Subcellular Localization:
Cell projection, dendrite. Cytoplasm, cytoskeleton. Cytoplasm, cytosol. Postsynaptic cell membrane; Lipid-anchor; Cytoplasmic side. Postsynaptic density.
Sequence:
MSTSGYWVKTARLDQGSVGTLSEAGDKLATVFVGVLTVSDRCYRRETEDRSGPNLQKIITEMKRFQVVIKVHKIVPDEKNEIKETLRDWSDRLGVNLILTTGGTGFAARDITPEATRLVIDKEASGMMVAITAASLKASPNAMLSRAVCGIRGSTLIINLPGSLKGSAECLRVVLPCLPHGLSLLREETKTVADDHFKIQLNEVATSLIAANVSQQTPFPQINSVIQQNGISPDDHAVSSFIHSYIKTVYLTSLLFIEKLYYINTNIFPQIRVTLDHHVPTHALSSDSGLLSADDLNTINLDIANDSLTNMVITCGLILARIDLLKPLLSVSHLAFCIITIFFNSCIISKKKFTVNICCIKVKALKETNGTQIPQKTNGKPESVVSGKHPQYDEFNVPRRQRTSPYPLLSMDEAFSSILTNVSTLPIISKYYSDAIDHILAEDIRAKAPIPPFPASVMDGYAVIGLDTPCDLDIVGASVCDRNNSNHSKGIRIGKGQAFRINTGAPLPLGADAVIPVEDTVLLKETENGKEELTVRVLKLVRPGENVRPIGCDIKTGEVVLKSQTKIGPSECGILASVGATTVKVYQKPTVAVFSTGSELATPDTENLGPGEIRDSNRILLITTLQSNGFKTLDFGIVPDQPKDLKATILSACEKADVLVTTGGVSMGEKDFLKQLLVKIGAKILFGRVFMKPGKPSTFATLETGQRKKCIFALPGNPVSAVVTCNLFVLPALRKLSGFQEPRPTILSAKLSSDVRLDSRPEYQRVQLRWEPREPIPWAHSTGRQVSSRLLSMLTANALLMLPPSSDACKVIKRGEIVEAMVIDRF
The following text describes a protein:
Function:
E3 ubiquitin ligase required to protect genome stability in response to replication stress. Acts as a key regulator of interstrand cross-link repair, which takes place when both strands of duplex DNA are covalently tethered together, thereby blocking replication and transcription (By similarity). During mitosis, controls the choice between the two pathways of replication-coupled interstrand-cross-link repair by mediating ubiquitination of MCM7 subunit of the CMG helicase complex. Short ubiquitin chains on MCM7 promote recruitment of DNA glycosylase NEIL3 (By similarity). If the interstrand cross-link cannot be cleaved by NEIL3, the ubiquitin chains continue to grow on MCM7, promoting the unloading of the CMG helicase complex by the VCP/p97 ATPase, enabling the Fanconi anemia DNA repair pathway (By similarity). Only catalyzes ubiquitination of MCM7 when forks converge (By similarity). Also involved in the repair of covalent DNA-protein cross-links (DPCs) during DNA synthesis: promotes ubiquitination of DPCs, leading to their degradation by the proteasome (By similarity). Has also been proposed to play a role in promoting translesion synthesis by mediating the assembly of 'Lys-63'-linked poly-ubiquitin chains on the Y-family polymerase POLN in order to facilitate bypass of DNA lesions and preserve genomic integrity (By similarity). The function in translesion synthesis is however controversial (By similarity). Acts as a regulator of the spindle assembly checkpoint (By similarity). Also acts as a negative regulator of innate immune signaling by inhibiting activation of NF-kappa-B mediated by TNF. Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFNB1 production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation (By similarity).
Subcellular Localization:
Nucleus, nucleoplasm. Nucleus, nucleolus. Chromosome. Cytoplasm. Cytoplasm, perinuclear region. Note=In the nucleus, found in close proximity to PCNA, suggesting localization at replication foci. Localizes to DNA damage sites in response to replication stress (By similarity).
Sequence:
MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKKTIINKLFFDLAQEEENVLDAEFLKNELDSVKAQLSQKDREKRDSQAIIDTLRDTLEERNATVESLQNALNKAEMLCSTLKKQMKFLEQRQDETKQAREEAHRLKCKMKTMEQIELLLQSQRSEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKATGELADRLKKDLVSSRSKLKTLNTELDQAKLELRSAQKDLQSADQEITSLRKKLMILQGTLSLPPATNETVSRLVFESPAPVEMMNPRLHQPPFGDEIDLNTTFDVNTPPTQTSGSQHCLPKKLCLERARSPMQNVLKKVHKVSKPESQLSLGGQRCVGELDEELAGAFPLFIRNAVLGQKQPNRTTAESRCSTDVVRIGFDGLGGRTKFIQPRDTTIIRPVPVKSKAKSKQKVRIKTVSSASQPKLDTFLCQ
The following text describes a protein:
Function:
Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
Sequence:
MRRALELAGAEVGSTGSNPAVGCVLLDAEGTTVATGVHRGPGTPHAEVDALRRARGRHRGTTAVVTLEPCDHQGRTGPCSKALIEAGVRRVLYAVADPNRVAAGGARRLADAGVEVVGGVLGAEAEAVLEMWLTAVRAGRPFVTWKFAATLDGRSAAADGSARWISSAESRADAHELRARHDAVLVGSGTWRSDDPRLDLRHGVVGHPPLRIALDARGELPPDSRLLDGAAPTLVVTDPATGTADHGESESNNNSGINTSTNTSTSRGANSGPDVLRLKTDARGHFPPLDLLAALDGRGVRSVLVEGGPALAASFVRAGLVDRVVAYVAPLLLGSEGVSATGPLGIGSIREAHRFRITSVDRIGPDLRIELRPPARTGGTQ
The following text describes a protein:
Function:
Controls stomatal patterning.
Subcellular Localization:
Secreted.
Sequence:
MMSPLGLFKVAITVSFIFPLIVLLPRSGRTVLCDEMRRESSLEERKVAIGSKPPVCVNKCMKCRPCMATVVVNDHDHQRKRKMKGFKLESSQEDDSYYLLSWKCRCGNKLFQP
The following text describes a protein:
Function:
Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
Subcellular Localization:
Cytoplasm.
Sequence:
MYGFVNHALELLVLRNYGPDVWEDIKREAQVDVEGQFLVRIIYEDAKTYDLVAAASKVLKMDAGGILQMFGKMFFEFCQESGYDTILRVLGSNVREFLQNLDALHDHLGTIYPGMRAPSFRCTDAEKGNNLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIEMKVIQPKSEECDHIKFLIEEKDSEEEAFYEDLDGFEENGTQETRISPYTFCKAFPFHLMFDKDLMLTQCGNAIFRVLPQLQPGVCNLSSVFSLVRPHIDFSFHGILSHINTVFVLRSKEGLLNVETAENEDELTGTEISCLRLKGQMISLPETENILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALEDEKKKTDRLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASAEGAIKIVNLLNDIYTRFDILTDSRKNPYVYKVETVGDKYMTVSGLPEPCTHHAKSICHLALDMMEIAGQVKVDEDPVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLQSVENADPQFHLEYRGPVTMKGKKEPMKVWFLSRKT
The following text describes a protein:
Function:
Capsid protein self-assembles to form an icosahedral capsid with a T=7 symmetry, about 69 nm in diameter, and consisting of 60 capsid proteins hexamers and 11 pentamers. The capsid encapsulates the genomic DNA.
Subcellular Localization:
Virion. Note=Main component of the capsid.
Sequence:
MNKPDLIEKQNRLAELKENNVSLKSQISGFEVKNAIEDLPKVQELEKTLSENSIEIIKIENELNAQEEKPKGKDKMTNFIESQNAVTEFFDVLKKNSGKSEIKNAWSAKLAENGVTITDTTFQLPRKLVESINTALLNTNPVFKVFHVTNVGALLVSRSFDSANEAQVHKDGQTKTEQAATLTIDTLEPVMVYKLQSLAERVKRLQMSYSELYNLIVAELTQAIVNKIVDLALVEGDGTNGFKSIDKEADVKKIKKITTKAKSAGKTPFADAIEEAVDFVRPTAGRRYLIVKTEDRKALLDELRQATANANVRIKNDDTEIASEVGVDEIIVYTGSKALKPTVLVDQKYHIDMQDLTKVDAFEWKTNSNMILVETLTSGHVETYNAGAVITVS
The following text describes a protein:
Function:
Involved in the regulation of carbohydrate metabolism. May act as a transcription factor.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSNLGNNITERIESDCISQNECRIDVYFSEKEKESTEASINMFLAELERLQLEYGKEHIWQNEELNLQRVEYQGKDCILGITNFGDCIDDEWYIVWLLREASKAVKSAFVRIIDEDGEFLLIEAALSLPKWIDEDNSDYRVWIHNGEVIILRPEDEFLKKMNRCPPLTREQAIFQISSGSNLYTSREVNDSISQRLKKFPKAANVKLRAICTVPRKIVHVLQKNKNLISSAVNAFYYRDPIDENYCDRMSKFNQNDLVTTTITFTPLLYAQLYQQRCKTFRPFHLPSDVHSLDYERAILGMKLSCGFEILYNSKENVEKRTEIDEYLQIQPLPTDEDIKKIPLIEDDTSFMNVNPDELEELLEKKLNSFCDDFGDDERSGFDNTDHDNTLVGEEEMVPGNHGGKSINEEITKNKQKQNFNESDLKNMASRIETFINDEASNNHREDFYGVKNSDTDTDSDSLADSDDEIFLNRNQGIDEVEFDETKFYDLLKGKDGKYQNQDVDEFSSGNEDEMDIPGDANMEEYMRAMDEELYGGLRGRDEGLEGIDDKDIDLNLMKNIIEGIEANPDLYGGPISTLLNSLKIQIPREK
The following text describes a protein:
Function:
FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-polyprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid. Also acts downstream of coq4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-polyprenyl)phenol to 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to coq6 from NADPH via a ferredoxin/ferredoxin reductase system.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MISRFVRTLATSAKFQDVVIIGGGPAGLTLLAALKTSPKTKHLQCTLIEGSSLDNVRKFHNDPPADYTNRVISLTPKSIEFMQNKVGSWDFIHEDRVKAYDGIIAYDSQDANSRIEFDISTIGQSTLAAMCEVINIQSSLLAKIESLQDKSTTIKDNTKVVEIVNPIEPDLDNHNLTEIDTNVSDPKLDWPIVKLENGETIQTRLLVGADGYNSPVRKYAHIESRGWQYNTFGVVATVKLQYEDFRAVGWQRFLTTGPLAILPLSEDNATIVWSSTPELADLLLKVNEKIFPHLVTAAMVLEEVDLNYIYSVLQEDPNDFSVLKDIEWRLSKFNPEELEERYPLPVVDVLSGSRARFPLKMSHADTYVAPRVALVGDAAHTIHPLAGQGLNMGQSDVAALVEALEKGIDRGMDIGSTLVLENYVANAWPSNHALLGICDKLHKIFSTDFYPLVWARGFGMKSINSFGAIKELMMKSISGR
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MKPQRYLMDFNLSKSYLPQKIQANRESSAKKLSNSEVNAAMQKYFQLLKKKESKVQHPIITPTQSSKILSQLVTKVSPQLDIQYPVKPPTPTGTQSYRPSTEKKPHHRPQQSVGQSKDLILKKLQSALFQKPKTQSQQVTPKSAGKGSLSVNKYFESTKKLNQDQPQYYITKVKNAFTKPIHDDYFSRMYREHFFQTYQGIYVASYLSPADPKDLKNKQVRLKQKDIYKNKISIVFDLDETLVHCNESLAIPSDVILTIQVSPQETIKAGINIRPGAIKLLELLVNDFELIIFTASHPCYAQKVIEYLDPNKTLISHSLYRDNCIMTTGGMYTKDLRIFDRPLSQLVLVDNASYSYAWQLENGIPIIPFYDNKEDKELESLLKYLRGMQGCRDVRDYNKENLKLHNFSDPSGPGAVFEKLFQQKMEIQ
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MIIRQLDYELFLWLFFAGWSYNNDNPREEWHLIPGSYCNGTSQSPININTSIAIHIDLGSLSPDGYTEANPNLEIVNNGHGITVQLHEAVEAFYTLSGGGLPTTYTASQFHFHWGSINSQGSEHLINSNAFPAELHMVHYDRAKYANLGAALTSLQWDAVTAVGVMIQIGEDENTAFKSVLDYVSQIANYSSGNTSLSLPSFSIRSVLPFDLARFYRYNGSLTVPNCYESVIWNVLEEPISISQAQLDTLRNVYGDTRDSAGNYETTVNNYRLVNPLNDRTLYYSRPEDQGEGDETSTPEPTDGGAVAISPMRALFIVALALCMLFNRF
The following text describes a protein:
Function:
Probable metalloprotease.
Sequence:
MPPTLLLSQDLPSLNYTTPGDRLDGRWRESLSTLLGLGRAAGADFVEFFLEKVNYVSCLAEDDAITSLTPRLSSGCGVRVYKGKGDCYVSTNDISFNGLRTALEKGLSILGLTLPAGQSFVPELNLEMLRDYAGAKEKDQWLHRCSPMQEMSDILLGANQKLDHYASHAQSRRAAYFRDWQEVLVAASDGTFARDIRLTQSVGFSLFCADGEHRTSIGKRSGDTSNPDYLRTWDAETSAQEVAESAGKMLYADYVESGNYPIIMANQFGGVIFHEACGHLLETTQIEHKTTPFLDKKGEKIAHENLTAWDEGLTDNAFGTIDMDDEGMPTQRTLLIENGILKNFIADRTGSIRTGHPRTGSGRRQSYAYAAASRMRNTYIAPGNYSVDDIFNSVEKGIYCKQMGGGSVGATGEFNFAVSEAYLVENGKLTKPLKGATLIGTATEIMNKISMSSQDLGLAAGFCGSVSGSVYVTVGQPHIKVDGITVGGR
The following text describes a protein:
Function:
Acrosomal protein that maintains proacrosin (pro-ACR) as an enzymatically inactive zymogen in the acrosome. Involved also in the acrosome formation.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle, acrosome.
Sequence:
MRHLAAGSFLSLLRVLLLPLAPAPAQDSASTSTPGSPLSPTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYENHGLVPDGAVCSDLPYASWFESFCQFTQYRCSNHVYYAKRVRCSQPVSILSPNTLKEVDSSPEVPPPTTATSPKSSHVTATERQVFQPWPERLNSNVEELLQSSLSLGGQEQGQEPKQEQGQEHKQERGQEHKQEEGQEQEEQEEEQEEEKQEGQGTEEALESVSRLQADPEPKFRSELVSSNPFSFTPRVREVESTPMLMENLQELIRSAQEMNEMNDVYDGETIWRSQSPGSLLQLPHVEALLTLCYSIVENTCVITPTAKAWQYLENEILGFGISVCDSLGRRHLAACTLCDFCSLKLEQCHSEANLQRQQCDSSHKTPFVSPLLASQSMTIGTQIGSLKSGRFYGLDLYGGLRMDFWCARLATKGCEDNRVASWLQTEFLSFQDGDFPTRICDTEYVQYPNYCAFKSQQCMMRNRDRKVSRMRCLQNETYTVLTPDKSEDLVLRWSQEFSTLTLGQAG
The following text describes a protein:
Function:
Involved in the binding and/or turnover of quinones at the Q(B) site of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating a proton gradient subsequently used for ATP formation.
Subcellular Localization:
Cellular thylakoid membrane; Single-pass membrane protein.
Sequence:
MTPSLANFLWSLVLGAAIVLIPATVGLIFISQKDKITRS
The following text describes a protein:
Function:
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
Subcellular Localization:
Nucleus.
Sequence:
MSLPGLNFSTTETNTTESTHTIDLKPETEWRYEVAIGGTLHVTLKSGTAEIFGTELPPNKELSIQGKGSIYTWQGCQFVYTAIAGPKGLMSDYTTEDTPHMTMAINLHFALEKMRNEAEQKPKDVAGPRVLIAGPPNSGKTSLAKILLAYATKCDRKPIYISLDPTSVNLGPPGGVHAVQITDLLDVETYGGFGSSEISGPQKLQPLILLSKYFGLEKTTDNFKLFKRSVAQLAVPVLSKLAHDVEAQKSGLIIDTPRVPGNQNKTIEVNLLTDVVSDFGVNVIVVIGNDRLYADLMKKYPVGASGPTVVKVPAFACMDDDESYNRDAQQQEIQQYFYGDAKDMKLGPRIVTVDFSTLHVYKIKPSTQFDDDKADMLERVAEANILPNTVLTVMHAVPGSSEKEILDSEVQGYLHVTEVDEEKNKVKILTPVPGRLPSQVMLLGDTRYHE
The following text describes a protein:
Function:
Probable transcriptional factor. Binds to the promoter of the SQUAMOSA gene.
Subcellular Localization:
Nucleus.
Sequence:
MKKTAADHQSQDHDLFGGGGAPDQEDKRKRAASGGGATNTKKSSGGGGASSTMKSCQAEKCSADLSDAKTYHRRHKVCEHHAKAQVVVVAGIRQRFCQQCSRFHDILEFDESKRSCRRRLAGHNERRRKNPADSYSQGAAEGGGSSSSTTTTSRIKGGSSNTSSGHVQENANNYNKHFHIR
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDAAWVLLQVRFSRLFFFFSFSLRWRLVQDGVGLASSCVRLCAREPCCPNPSCSVPEPGSLKFGTLRYLSLLPTLDPSQCGEWLPWAPGQVGSHRCLSPPVPPCSRGAAQRTCHYQGHGSVLESRCEAQKLFLKKELCEIEMAQWEIMRKLTRQNLQCSSLSGAREWNGHCERLRGSQERQFSELIINREDVPTLSHYPSLRLQQTVRSKEKYCASKENRQHCKHASLFSPHQIIRTTEKPYECKDCGKTFRHPSGLTHHHKIHTGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKDCGKAFSSGSNFTRHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHAGKKAYEDEDCGKSFKYDSQPVQHQNLYW
The following text describes a protein:
Function:
Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space (Probable). Determines the precise timing of host cell lysis (Probable). Participates with the endolysin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell (Probable).
Subcellular Localization:
Host cell inner membrane; Multi-pass membrane protein. Note=Classified as a class I holin.
Domain:
The C-terminus acts as a cytoplasmic regulatory region.
Sequence:
MTAEEKSVLSLFMIGVLIVVGKVLAGGEPITPRLFIGRMLLGGFVSMVAGVVLVQFPDLSLPAVCGIGSMLGIAGYQVIEIAIQRRFKGRGKQ
The following text describes a protein:
Function:
This protein is transferred from male to female during mating and may affect egglaying and behavior after mating.
Subcellular Localization:
Secreted, extracellular space. Cytoplasm.
Sequence:
MNYFAVICIFSCICLWQFSDAAPFISVQSSSQSRSQKVMNGMLRTLYDYSVQDSVNDATGHLIQTHKADFNSDVMSPDEIESVRQQLNMA
The following text describes a protein:
Function:
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular Localization:
Nucleus.
Sequence:
MEPPASDSHKSQLNALERRKKYNELLDYGHELALRTQTEDAVGIFQGVSSILIQTDQLHQSMAAEKMENASEMCINVQVVKMGHDLVGAALQKSESTQFCDEELAAAIVPIIGDSGNPLQWLHIGELGIKSFSMSKQSPCLLGAFELEPVQVEKPVKERRRRQRQELGDPRKPETVVKLNQEETDARKLQGVMEQLKAIYEERRQPIPYFELITDPTDYMNTVDTAFQISFLIRDGAVALETVDDLLSVRPTSSSEKQQNKRTDDNVQAILSLNFAKWQSAVKQFRLKRPLLAIERDTLDASQAS