The following text describes a protein:
Function:
Structural component of the egg vitelline envelope; forms long filaments. Functions as a species-specific receptor for the sperm protein lysin; prevents fertilization by sperm from other species. Each VERL chain can bind multiple copies of the sperm protein lysin; this creates a 3 um hole in the egg vitelline envelope through which the sperm passes.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Secreted, extracellular space, extracellular matrix.
Domain:
VERL repeat 2 is important for species-specific lysin binding, even if it has lower affinity for lysin than VERL repeat 3. VERL repeats 3 to 22 have high sequence similarity, indicating they all can bind lysin equally well, but they do not play a role in species-specific sperm selection. VERL repeat 1 does not bind lysin.
Sequence:
MSGMQWSFGFSCLFFLKTVWICQAFDADTPDPRVLSLDLTLVCSDDKSKQATLISYPVTFKGHVIKDMQIFCKNGWMQMTRGRGINMIRIHYPQTYTSVVPGACVFRGPYSVPTNDSIEMYNVSVALLWSDGTPTYESLECNVTKSQASNAPEPKASPTSSTPQPEAASHNQSKLIDWDVFCSQNENIPAKFISRLVAPKCLAVEKMDVDCSNGLVPITHEHGFNMMLIQYTRNKLLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTDLSIQCYMPKSPDAPKPESCLSSPPEPEASPSSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQDESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIQCYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPSSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHKFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAHKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLPIECYMPKSPVAPKPETGPSSNAPEPETYPTSSAPEKVYSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPQTYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPQTYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPQTYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESFPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETGPTSNAPEPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITQEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPETYPTSSAPEKVSSDQPAPSHNQSKLIDWDVYCSQNESIPAKFISRLVTSKDQALEKTEINCSNGLVPITHEFGINMMLIQYTRNELLDSPGMCVFWGPYSVPKNDTVVLYTVTARLKWSEGPPTNLSIECYMPKSPVAPKPEASPTSNAPEPQTYPTSSAPGTSPEGSATAAPGTSPEGNTTAARNAYPRKSNQTTSTEDVLDDTSNYIIKVIPHCRTRGDVALIEIITDVDLSAVAVCSNGSRHHFNSTDFVHFYLPVSYNFTPSVCAFTRSKANLFKLHIGVSWKDRLHDVTTQKKDFLITCTFDPHKSHRGPTSASSEPLIAAKEIQSHQGPQSDAEEVFLKLVDIRNETLAAAVPLSKKVRLVGEVHGSSLESGLKPVACDAVGVQQGQRYTILRDGCGDGIVFAKDIGFITEGNKAFSPVFEVFKLHGNLHLTFMCNFTLCSHSCDGSSCSNQRRTRRSMAWQDIPHVADFDSSATPSTDMATVQVALLVAVALLITQLAGLAIYVNIN