lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.
Subcellular Localization:
Cell envelope. Cell membrane; Lipid-anchor, GPI-anchor. Membrane; Lipid-anchor, GPI-anchor.
Sequence:
MRLFSLALAGMQFLAMTAALPNITRTGKYLYDESGNRFYIKGVAYQPEGELAASSDANSANGGFPEPSSFHDPLSSPQNCTRDLPYLQQLGVNAVRVYSVNSSLNHDDCMKMLNDAGIYVLLDVSLPLNGSIDRSSPSWSTNLLNEYIETIDAFRSYGNVLGYNIGNEVINLVSNTNAAPFVKAAARDIKAYLKSVGSSALVGYAAVDGESDFRNSLAEYLTCGGDSIAVDLYGLNNYEWCGNQNINSSNWNTITEGFSDLPVATYMSEFGCITSPPRLWTEVAALFASPVSDVFSGGVAFSYFPTSDDYGMVTISDNDTVTVTDDFTRLATQYNSTSPPNSPAKSSVTANETNCPAESDSLLASSTLPPTPNESVCNCINENSLSCKVKQSSANSPEIVGALLDYACSLLGSTNSSASCDPIAGNGTSGTYGQLSFCSPAIKLSYVMSTYYQINPEDTSCDFAGNASLSTNRPNTAQDANAAASSCLAAEPSGGVFTPTAPGSGAATATTTGTASGSTSSSASTSDSSASTSGDIKSITVVGGVLTAVVGIAGVVVGGGAILL
The following text describes a protein:
Function:
Potential transporter for phosphate.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MISALLGVGLVVAAFVGFNVGGSTTGPAFGPAVGADALSKPTAAGLMTVFFFIGAWTLGRRVVDTLGTELLRQPGIFTLEASIGVLFFIGLALFVGNYAGVPASTSMTAVGAIAGLGLARDALDVAVMGEIVIWWVVAPVIGFWVSLIIGRYFYARLHRRVAMNRTEGALLRVDRTGAIPTVRPAENTNRRELFGVVTVITIGCLMAFSSGTSNIANAIAPLVGSGVVGMNPAILLGCAAVGVGSFTIARRTLETMGSDITELPLTAAIVVASVSATLVIFLSAIGIPASFVVIATVSIVGLGWGRATRPVSVQSAVSGDSDVAVSVGGLAADDPDEAVPAIGEEQPEDIPSAGDLFDPGTTVRVIAMQNLVPIVGTVSAYLAFRFLPIWGF
The following text describes a protein:
Function:
Required for the development and function of the thalamic reticular nucleus (TRN), a part of the thalamus that is critical for thalamocortical transmission, generation of sleep rhythms, sensorimotor processing and attention. Can bind cholesterol in vitro.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell projection, dendritic spine.
Sequence:
MLRQVLHRGLRTCFSRLGHFIASHPVFFASAPVLISILLGASFSRYQVEESVEHLLAPQHSLAKIERNLVNSLFPVNRSKHRLYSDLQTPGRYGRVIVTSFQKANMLDQHHTDLILKLHAAVTKIQVPRPGFNYTFAHICILNNDKTCIVDDIVHVLEELKNARATNRTNFAITYPITHLKDGRAVYNGHQLGGVTVHSKDRVKSAEAIQLTYYLQSINSLNDMVAERWESSFCDTVRLFQKSNSKVKMYPYTSSSLREDFQKTSRVSERYLVTSLILVVTMAILCCSMQDCVRSKPWLGLLGLVTISLATLTAAGIINLTGGKYNSTFLGVPFVMLGHGLYGTFEMLSSWRKTREDQHVKERTAAVYADSMLSFSLTTAMYLVTFGIGASPFTNIEAARIFCCNSCIAIFFNYLYVLSFYGSSLVFTGYIENNYQHSIFCRKVPKPEALQEKPAWYRFLLTARFSEDTTEGEEANTYESHLLVCFLKRYYCDWITNTYVKPFVVLFYLIYISFALMGYLQVSEGSDLSNIVATATQTIEYTTAQQKYFSNYSPVIGFYIYESIEYWNTSVQEDVLEYTKGFVRISWFESYLNYLRKLNVSTGLPKKNFTDMLRNSFLKAPQFSHFQEDIIFSKKYNDEVDVVASRMFLVAKTMETNREELYDLLETLRRLSVTSKVKFIVFNPSFVYMDRYASSLGAPLHNSCISALFLLFFSAFLVADSLINVWITLTVVSVEFGVIGFMTLWKVELDCISVLCLIYGINYTIDNCAPLLSTFVLGKDFTRTKWVKNALEVHGVAILQSYLCYIVGLIPLAAVPSNLTCTLFRCLFLIAFVTFFHCFAILPVILTFLPPSKKKRKEKKNPENREEIECVEMVDIDSTRVVDQITTV
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDTVVFEDVVVDFTLEEWALLNPAQRKLYRDVMLETFKHLASVDNEAQLKASGSISQQDTSGEKLSLKQKIEKFTRKNIWASLLGKNWEEHSVKDKHNTKERHLSRNPRVERPCKSSKGNKRGRTFRKTRNCNRHLRKNCCTSVRRYECSQCGKLFTHSSSLIRHKRAHSGQKLYKCKECGKAFSRPSYLQTHEKTHSGEKPYACQSCGKTFLRSHSLTEHVRTHTGEKPYECGQCGKGFSCPKSFRAHVMMHAGGRPYECKHCGKAFRCQKSFRVHMIMHAGGRPYECKQCGKAYCWATSFQRHVRIHNGEKPYKCGKCGKAFGWPSSLHKHARTHAKKKPVSGGSVGKSSARPRPSTDVKSQTREKVYKCETCGKTYGWSSSLHKHERKHTGEKPVNAASVGKPSGGLCSSKNVRTQIGQKPSKCEKCGKAFSCPKAFQGHVRSHTGKKSCTSK
The following text describes a protein:
Function:
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Miscellaneous:
MISCELLANEOUS: Present with 5410 molecules/cell in log phase SD medium; MISCELLANEOUS: There are 2 genes for uS14 in yeast.
Subcellular Localization:
Cytoplasm.
Sequence:
MAHENVWFSHPRRFGKGSRQCRVCSSHTGLVRKYDLNICRQCFREKANDIGFHKYR
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MNDAQIKDMMNDEEEKEEIEIKENINDKINEIDDNDDNDDGDDDGDDDDEDEDEDSDDNDDEDNDEDEDNDDNDDNDDSDNNDDDHNDVKKSSKNKKKNNEEMFDRSNHFDNFDNIMLDVRLRKALLYLFKYQHPTIIQKMSICKILNGHDVIISSKTGSGKTMAYLIPVVHNLIKFNLNEKDHLKFFYKCIIICPTEELCLQIYDVTKKLCTYLKDIITVNHNVNNTFYEHPTILISTPKDLCTHIIEKKKKNNLDILMNLKILILDEADVLHTQEFQSYLKTLTSYLPKKFNKKYQIVMASATLKRNILEKTKLFLHNPIYVSHEQKNESSFEKKKNKTNNTNSVIMKREEAGKNNIHDEGNEGKTKYQKFTGKAFYYVYKEELIKYIYLYNLIKIKIIPYKSIIFTTTIHDAYKIKIFLTYLNVSSSILNPNHPILIRQNIISAFNNSKFHFLICPQYEKNNMKHVKGVLGSNKMDNVDGGDDNDDDEDDGDYNDDDDNDDDDNDDDNDDDNDNDDDEDNDEDEDNDDDDGDDNDDDNDDNNDDDNDNDDQTLNEPLSDNNSCRTYNSDDENEKTDDTTKLNEEKDFLYSRGLDFYDVKCVVNFDMPSDSETFIHRIGRTCRLNNKGKCISFVNELNYGEKEFLQKLIEDKNICTMIKKNIQYNIVEKYRYRVESTLNKCTNKKIKLFIQKEILYQSLKSKELKDFFNTNINEKRKINKIIKHFNKAVIPQKLIKDRNQSIFLNKSKVKNKIIQKNNTNNKNKNNNNNIKPFALKNNNGLVITEQGYESQLTKEPEREVADPSKLPPLCGQRLRNYMYLKYIKGKKNKNGSNMNKSYNSNNKKRKNNNKYNNRYNKYNKKGINKNHNKRNTNFNR
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MGMWEEASDTGMKGKKKDKNERNKRILNLTLEMIYLLTGEEWVRFNKDHSLITEGIKEESQQLQPQDCEYEDKRDITADLGGTLCYNNETSKIGAEGAHFFADGNVEQPPTVSDIKEEPVSLEERNQSDCSINPHTEQIQGTDTTTPIMGCSLKNSLSANYILDNIKEEADTSEISILLCNSASNSVKIEVVSHEEGNQSDCSINPLTEQTQGTDTPTPIMGCRMNNSLSGDIKEEVTLCAEGNQSDCSFNPLTEQIQGTDTAAPVLNNSSSDHIAGAIKEEESDLSDLTIITVSEPTPITGCSLSTDYRTNSKKLRARKHPDEKRNNAASKQTCTDRICEHGVQGKCNNATCYKGFHRKEVNLRQRKNRTGLISIPVPDYRENFDGQQRTHTEDTPHSCSECGKCFKQISSLIVHQKTHSEESKFSCSECGKCFPRLLLLNMHHKSHKRVKPYLCYKCGKCYLQLSDLNAHQCSHRGEKPFPCSVCGKCFTQSSELNLHQKLHSEDKAFTCSECGKCFSRLSSLTVHQISHTGDQPLSCSKCGKCFTYRSQLIVHQRSHIGIKPYSCSECGKGFTQLAHLNAHYRVHQS
The following text describes a protein:
Function:
Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.
Sequence:
MSEDQGQQGQRLSTARGSTCLKQTMTEPALSAGLGTDGPVGAAKDNIRVRIQSRRRSRLLSRLGRKIPTQGRFTVGWYFWFLLIYTSLAVEPVKSHETHSHSSDAEGTSHQDVSDRRNHPCHTPRPSSHSQADSFESVARGQQKEQSRTMREDAVSPVLLDVKRSQSTPVELAKLVSLKLSTSFGSRTVIRRSQPGVRQSVRAAQLQRMMLDRGNPKRERSSGSSTPSSKSSPVDSVSTAPTSVSPGSLAPSGSTNNDPASGFKHIDSQADLPERPLSPVRESPMVSPTIQTTEATAIVKVFLETHFHTLLSGLDARTQRRLELDQYIETFPLSPEEVVRVRKHWVTQERDYLRQYRVLKSRPQDKTSRAGTASLAGFEPLKILGRGSFGVVRLVREKRTDEQTQSGRVPLAPKTNHRQAMTGVKKDVFAMKVIRKSVMIRNCQEAHLRAERDFLVASAKSRWVVPLIASFQDQKHLYLVMDYMVGGDFLGLLIRHNILRESIARWYVAEMILCIEEAHRLRCIHRDVKPDNFLISESGHLKISDFGLAFDGHWAHDQWYFTYQRHSLLKRLGIQIDGDAEDQKLSHDANIQSLGTTREDGSMEDDWIHPPTNGLLHWRDKNQTRTMARSVVGTSQYMAPEVIRGHPYDGRCDWWSLGVILYECLYGFTPFASEDRHQTKLKIHRHLQTLYFPVHRPTDKLVSADAIDVINSLLQEKEFRLSSPKYKQNDAISSKPAKCSFYKPDSSNPSYQGHYVYPDDATDIKSHRFFRGINWEQIHRTSPPFIPMVRGWEDTRYFDDGEHPSDREDDSSDSELDGVQDKWHPLGGKGGLHKPDKPLKADVKPSSYPKGNDGAKDTAIASLKHKKRLKEAKRARDKILRDKRLRRTVLEMLRCLVVVAAT
The following text describes a protein:
Function:
May act as an anti-Gre factor.
Sequence:
MSRPTIIINDLDAERIDRLLEQPAYADLPIADALNAELDRAQMCSPQEMPNDVVTMNSRVKFRNLSDGETRVRTLVYPANMTDSSTQLSVMAPVGAALLGLRVGDTIHWELPGGASTHLEVLELEYQPEAAGDFLR
The following text describes a protein:
Function:
Has antimicrobial activity against E.coli. Plays a role in the defense response in the male reproductive tract, contributing to sperm maturation, storage and protection.
Subcellular Localization:
Secreted.
Sequence:
RQRLLPFFTSLLLVALLFPGLSQARHVNHSATEALRELREGATGQGTNGSQLLRHPGKRAPIIRRIPYYPEVESDLRIVDCKRSEGFCQEYCNYLETQCTSLTRRLEDPDLRAAWAF
The following text describes a protein:
Function:
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MQGFLRSLFFGVKKIPKPFAPLVEKGVLKEALELKKDRYFLKEGFDIGKVEKVKDKAFFISLAKNYPKDPLIKNLPPSFKTDALILCQIECSKKRPIAFFKAALLNADHTMIAYLAKKNNQIVAIPFKEPFKKPVSLKHSQKSLLELPRHCVVKIDTKKREISEILGALEDPLIDENLSLSLFDRVKDFSKDCLNLAQHYAQLKASDFKDRINYSHIPFITIDPKDAKDFDDAIFYDQEKRVLFVAVADVSEFVPKHSSLDKEARVRGFSVYFPNSVYPMLPLSLSQGACSLKAFEKRLALVYEIPLDNLKNARLSQGVIEVRANCTYEEINHFLSANQSSLDKDLQQSLLGFLEMALKLKKERLKKGFNFNSFENKLYLNKEGRIEKIETEKESDAHTLIEEAMLLANQSSARLLDEHFHNKGIYRTHKEPSLEQQKRLYDKLFDYEIVRPKNMGFFPFLEHALKIAKEKSIEREVSRLIIKSQNLALYSPLQESHFGLGFASYTHFTSPIRRYSDLALHRLLKELLFYQAKGCSYLLEETPELCAELNALQKKAALIERDFIKRKFARLALELLEKEFLGVVLEVKDWVVVGLKEFIGLKVLVKTNKVFKPLEKVRVTITHADLILGQVRGEITERIKEHVS
The following text describes a protein:
Function:
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
Subcellular Localization:
Cytoplasm.
Sequence:
MQCQFEQKFKLKISMENFPQLYSKERLHSFITKYKDLIQLDPHKELHCGIIHLDELHIAAQLLHQGELVAFPTETVYGLGANAKNAQAILNIFKAKKRPLSDPLIVHVHDKNNIYTDKPDFLDSFAELFWPGPFTIVLKSTQLETTEILSAGTGSIGIRIPNHKVALELLEKANLPVAAPSANLFTHISPTSAAHVFNDFYDQRVHIIDAGRSDNGIESTVIKPLGNELHILRLGSLAKETIMKKIGQSDKLKHFAIKYENKYMQIEETEEDIEKELEELNVLERKNSMEAPGQFLKHYSARINSFIVTFQSNTIGQQIDLDLKESVIIDFGSELKNRIADLDEIKYKSLSENYDAKEAMFNLYDSLRWAELQQGAKQILLYDFDTQINQKVQNDENVLSIQDKIFRSASGQKTYYNNNKFYLCQ
The following text describes a protein:
Function:
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells. May prevent intrinsic apoptosis, probably by regulating mitochondrial membrane integrity.
Subcellular Localization:
Membrane.
Sequence:
MSSPGGPPPPPLLPISLRRWRDAAAELGMVLRSVLGPGAARLLFYPTLLYTLARERVPGSRRPWFSRIDHAVLLGALPLRGRCRQLVDEENVRGVVTMNEEYETRFLCCSPQEWEAMGVEQLRLSTVDLTGVPSMENLHKGVEFLLKHRERGNSVYVHCKAGRFRSATMVAAYLIQIHQWSPQEAIEAIAKIRPHIIVRNKQVQLLEDFHKCVTVGSPTQSEQKLQDGEHKSPEQMENNRLKTPGS
The following text describes a protein:
Function:
Involved in copper homeostasis. Can complement the yeast mutants atx1 and sod1.
Sequence:
MAQTVVLKVGMSCQGCVGAVNRVLGKMEGVESFDIDIKEQKVTVKGNVEPEAVFQTVSKTGKKTSYWPVEAEAEPKAEADPKVETVTETKTEAETKTEAKVDAKADVEPKAAEAETKPSQV
The following text describes a protein:
Function:
Acts as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi. Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the EARP-interacting protein eipr-1. Important for neuronal function.
Subcellular Localization:
Golgi apparatus, trans-Golgi network.
Sequence:
MSSVLDVTKPDFDVEAFVVKLLREKSLDGLVKEEEEMVSAVRRLDSDVHQIVYENYNKFLTATNTVRKIQDEFTQLDSEMKSLSRSMSTISTLIGNLDGVLGEKRDDILQLGSSYKVVNSLKHIFDLPHVLRSEFDERNYGEVLRMFKLAEESLSQYKDVPTVQLVLQKSKKIYDMTENQLMDQLRNPASGAELVSEAVDLLLTIGRDEDEVQKVLLTCSEQSLRVDLKELSANHSDVLDLVDKASESFIPNLTLIATTHDRLFEDKREDLITVLKTEMNSLHALVSKVFLSSSDAKDCSIVVRALDRYFRKISTCRYVIPGLDFLPLTIELINAVSKHEIDLSLTRIKEELKNGLNEVRKALINEEKDLSALASKIEQVFVHQVKTALANLLLFTASDVTFANLPPDEFRQSFSFNAHERLLVQAFHRFSELADEYESGAGEIRFVDPRVHLVFAVALQHLSNKSAVYLLNLCREQFSLSPDDGLTDITVVMSEVKTRAQKLVRCYAEKTGLSMGETLIKGCAMLVQPAATPSAVRASVRRLVEEMNTCDSELTLLLGGDSKPKDSRVSRRPITTALDAARDSLWCERIDFHLQIHFNRASIITVIVKVVLKIFIESIRLQTYSKFGVEQVQVDCYYLQRCLAALVSDEVVVNSMVDQALSSALKRCQDPVLVHPSRLAQLCEQPPANRPSSQASSLGY
The following text describes a protein:
Function:
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
Subcellular Localization:
Secreted.
Sequence:
QHWSYGLRPGGKRNAKNVIDSFQEIAKEVDQPVEPKCCGCIVHQSHSPLRDLKAALESLIE
The following text describes a protein:
Function:
Transcription repressor.
Subcellular Localization:
Nucleus.
Sequence:
MSEIEDLKNQIIQIDTLLAEEKDDVARRDLEQTKPDLLELVELMEEDEESQEGTSENAKEEKEAVEERIEDDNSTDTLLGSRCMAPFDSDRSLPLHTAIIMDIESSSRVRVLFSHPTCPAMKPCSHFLASTCRYNENCRFSHGYSVELERIEDYQEPDFMSIVEQGLVLVKGSSELWEIGRISAIDGQNVAVKLLKSGSEVSSKRKDLVPLGEIEEKEKKTNLGESGNWNVGGIGMKLMAKMGYKVGEGLGKRSDGIVHAIQARICAKNASLDEVMTRKRRVVDRKDKSKRIMILKTSDESEKDIFAFINRKLETKSERTMADVRKEKEEMAGYTSKALGSKKTRSGIRAETVAGEAKKIERRNSKEQK
The following text describes a protein:
Function:
Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
Subcellular Localization:
Cytoplasm.
Sequence:
MQNIPPQVQAMLGQLESYQQQLQLVVQQKQKVQLELTEAKKALDEIESLPDDAVVYKTVGTLIVKTTKDKAVAELKEKIETLEVRLNALERQEKKLNEKLKELTAQIQSALRPPTAG
The following text describes a protein:
Function:
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
Sequence:
MALLDFFLSRKKPTANIAKERLQIIVAERRRGDSEPHYLPDLKRDILAVICKYIQIDPEMLHVQFEQKGDDISVLELNVTLPETEETPK
The following text describes a protein:
Function:
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Subcellular Localization:
Cytoplasm. Mitochondrion. Nucleus.
Sequence:
MSLSLPSGWEEFIISMADELDEIVTILKREMDNGVIIFSALNDVLRAFYETPLSDVRVVMLGQEPYKGIGKANGLSFSVNKGYLVPPSLTNIFKEISDEIKSFHIPPHGDLTKWCKQGILLLNSALTTESGSNRSHDTLWQRFTKTCIRLCSAKGGVVFVLWRKTASTFDKEIDTSKNIILKAAHPSPFSANKGFFGCNHFTIINDLLDTPIDWNL
The following text describes a protein:
Function:
Plays a role in promoting mitochondrial enlargement in cone photoreceptor cells in a fusion-independent and ATP-dependent manner.
Subcellular Localization:
Mitochondrion. Note=Colocalized with tom20 in cone mitochondria. Uniformly distributed throughout all mitochondria in cone ellipsoids including mega-mitochondria.
Sequence:
MLASRALLAKQAAAMLVRQPACLMHHGGDWGNWGNTNIAVVFSGCGWWDGTDIHEAAYTMYHLSRNGARFQIFAPNQQQMHVMDHMKMQPSSSDNRNMMMESARFSHGQGMMQMNDLSKLDANSFDAVIFPGGHGIVKNMSTFSKDGKDCKLNNDVERVLKDFHRARKPIGLSSMAPLLACRVLPSLEVTMGYERDESSRWGRWPNTNMVQAVKSMGARHNTREPYEAYVDEKNKVISTPTFMWETDYHYHYIFDGIGNMVKHVMRMTAK
The following text describes a protein:
Function:
Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.
Subcellular Localization:
Cell membrane.
Sequence:
MIEAENVHFAYNGKEVLRGIDFEMGQEIVALVGPNGSGKTTLAKHFNGLLKPSKGRVLVDGLDTREHTVAELSRLVGYVFQNPEHMFFEETVFNEVAFGPRNLGLSEEEVEERVKWALKSVGLEGFEDRTPYSLSGGEKQRLAIACVLAMKPKYLILDEPTTGLDARAEEEVVEVIRSLHESGHGILLITHDMDLVVRLAERVVLLHGGRKLFDGPVEEFFTAFDVEKYGLERPEVVELGERLGVGFVRSIEEILAKLGGEV
The following text describes a protein:
Function:
Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MIRWKTTLSLLPLLSTALFVDDSIHHSIEYRIPDETSLLLQQEDDHHVVIQTRDQEQYTCALPQSNKEVDDDVNSYSGPTPWELIAPLKERNICTQRVDPFWSYEVCHGKYVRQFHESKEKLNFYLGNYHPKLSSYQYEKEKPNNDRIKVNGEELPYLPVVYSQGTTCDLTGQPRNTRVLYICYPVQRELIESITEVSTCKYDVVILTQLLCTHPLFRGAKTTINKIVCTSHNKESQPIPKSYTPLAIAQKAGFHASYAPTVDRVLKPSDSSSILDLTELYTKMERNHGFKKQADIRFDSSGLNEILSGTACLDSGGLDYWRYEYCHLNKIVQYHEISSTNRKEILLGVFNKEKHLKYLQDYPTKRPNKFDGKMVQVTLLYSGGMKCGDEPDKNFHREAEVRFRCSAKKNEDEMKTSKEDIEFSVIETSICNYIVTLESDSICRAIQGADINGLFSP
The following text describes a protein:
Function:
Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in neurite development and synaptic connectivity.
Subcellular Localization:
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Sequence:
MDFSKLPKILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWDFTPCKNLQVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALAANTSNMPVAARWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDILYKLSSMKFKDPLKDGEAKIKSDYAQLLEDMQNAFRSLED
The following text describes a protein:
Function:
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. MTR3 is part of the hexameric ring of RNase PH domain-containing subunits proposed to form a central channel which threads RNA substrates for degradation.
Miscellaneous:
MISCELLANEOUS: Present with 7380 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MNVQDRRRLLGPAAAKPMAFSNTTTHVPEKKSTDLTPKGNESEQELSLHTGFIENCNGSALVEARSLGHQTSLITAVYGPRSIRGSFTSQGTISIQLKNGLLEKYNTNELKEVSSFLMGIFNSVVNLSRYPKSGIDIFVYLTYDKDLTNNPQDDDSQSKMMSSQISSLIPHCITSITLALADAGIELVDMAGAGEANGTVVSFIKNGEEIVGFWKDDGDDEDLLECLDRCKEQYNRYRDLMISCLMNQET
The following text describes a protein:
Function:
AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates. This subunit may act as an adapter protein that links AcrB and TolC stably together. It is elongated in shape, being long enough to span the periplasm.
Subcellular Localization:
Cell inner membrane; Lipid-anchor. Note=An unlipidated version of this protein (directed to the periplasm by the OmpA signal sequence) functions normally.
Sequence:
MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVTVKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQSSNDFLRLKQELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITLRAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVETRPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAASGAQPEQSKS
The following text describes a protein:
Function:
NAD-dependent deacetylase, which probably acts as a regulator of gene expression believed to help form modified chromatin structures on the genes it regulates.
Subcellular Localization:
Nucleus.
Sequence:
MTGSPRAPHQEHALGEPTVEGLARYIREKDVRRILVLVGAGASVAAGIPDFRSSDTGIYAKLGKYNLDDPTDAFSLTLLREKPEIFYSIARELNLWPGHFQPTAVHHFIRLLQDEGRLLRCCTQNIDGLEKAAGVSPELLVEAHGSFAAAACIECHTPFSIEQNYLEAMSGTVSRCSTCGGIVKPNVVFFGENLPDAFFDALHHDAPIAELVIIIGTSMQVHPFALLPCVVPKSIPRVLMNRERVGGLLFRFPDDPLDTIHDDAVAKEGRSSSSQSRSPSASARREEGGTEDGSSSPNEEVEDASTSSSSDGYGQYGDYYAHPDVCRDVFFRGDCQENVLKLAECLGLREALAKRMRFSGAAPATARKTSNET
The following text describes a protein:
Function:
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKFLILSGPKALSDFRINNLIQEIEKKIGQSDIIDKVVGSFTHYISLQQEQGDLTDKQLELLKILLTYDNPLETDNDENSSLNKILIKNSTVIDGESIELPPNTYLIQILPRPGTISPWSSKATDIAQICGLKDQIERIERGLSLLIKTKNGFKLDQNNNNNNNDSGSNSNSIPIETLLTSVFDRMTQSIYFGNNVPQYNDLFAHHSPKPLVTIDIISDSENLIKANKELGLALDQGEIDYLINAFKEIIGRNPTDVELFMFAQVNSEHCRHKIFNADWTIDGTTKELSLFKMIKNTHEKTPQYTISAYSDNAAVFEGHEGYVWTPDFKTKQWKSIKEKVQTLVKVETHNHPTAVSPFAGAATGSGGEIRDEGAVGRGSKSKAGLSGFSVADLNIPTLPQPWERNVGKPNHIASSLDIMLEAPIGSAAFNNEFGRPAINGYFRTLTTEVENSHGETEIRGFHKPIMLAGGMGAIRPDLALKDTKITPGAKLIVLGGQSMLIGLGGGAASSISSGEGSADLDFASVQRGNPEIQRRAQEVINACVSLGKLGNPIQSIHDVGAGGLSNALPELVHDNDLGAKFELRSILSLEPGMSPMEIWCNESQERYVLGVAPENLDLFAKICQRERAPFAVVGVATEEQRLVLTDSLLNSTPIDLEMSVLFGKPPKMSRTAITSNLNLTPFETTNNNLDVSESIDRVLQLPAVGSKNFLITIGDRFITGLVDRDQMVGPWQVPVADVGVTATSLGDTILSTGEAMAMGEKPTLALISASASAKMCVAESLLNIFAADIPSLDHVKLSANWMSAASHEGEGAKLYEAVQAIGMDLCPDLGISIPVGKDSMSMKMKWDDKEVTAPLALTITSFAPVDNTSNTWTPQLQNLDEQQQEETVLVLVDLAASNEAGKSLGGSALAQVYKQVGDSAPTVHSHKILKSFLETLIVLHKQFDILAYHDRSEGGLITTVLEMAFAGRCGLDLNINGKQDVFTELFNEELGAVFQIKFKDYTKFQQIFLDNGIDENFIQIIGKPKFDSKQLIDISFNGTPIYSSTRGHLQQLWSNTSYHIQKLRDNPITSTQEYDAIKDDNDPGISYQLTYQPNEFKKYSSQQPKVAILREQGVNSQQEMAWCFQQAGFDVYDVTMSDILEGRTTLDDFVGIAACGGFSYGDVLGAGAGWAKSVLFHDKARQEFKKFFQDRNDTFAFGACNGCQFLSRIAELIPGTENWPTFEKNLSEQYEARFVMVEIESSPQKNNSIFLKNMKGSKLPIAVAHGEGRAQFKALQEQKDFQLDVIHYVDNYGKITENYPFNPNGSPNGIAGITNSNGRVLAMMPHPERVCRKESNSWYPIEQGKEWGQYGPWIELFKSAREWVGDNRN
The following text describes a protein:
Function:
Lipid-transfer proteins that possesses lipid-binding activity in vitro. Involved in the development of lipidic orbicules/Ubisch bodies and pollen exine during anther development. May be regulated by the transcription factor UDT1 in developing anthers and play a role in tapetum development. Positively regulated by the transcription factor TDR in developing anthers and may play a role in tapetum programmed cell death (PCD).
Subcellular Localization:
Secreted. Secreted, extracellular space.
Sequence:
MAPSKSTAAAGVLLVLLVAAAGGGAEAAATTCVASLLELSPCLPFFKDKAATAAPEGCCAGLSSIVKGEAVCLCHIVNHTLERAIGVDIPVDRAFALLRDVCRLSPPADIISTCANEKGGVPPLYSCPAPSA
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MGYFIRCLLVMLFHSTLVLGHRPLEKSHSLSLVTMVPLLELEKKLIDNLENYTNALEQKLEIIRSQLLVIRAENEKGRRNAISYLSNPLNGFSIIRRLHQDWINWRKYMEQPVGIWQLKAFYSWKDELPTERDLWDACEGIARIQSTYDLKVGDFINGNINGKQYNDSMSTADILSVGAYLFMKNRPSDAIQWLQEVPQRLQEELLIQPRHLPIKEVDALRLLAEAQIKDQNYSEALPLLHNCLKLQPHDARVLRLWKKTTDFIENQPDQSPTENKKRNVPIANAFKLSCNGPLESSTRLHCFYNFTTTPFLRLAPLKTEQIGLDPYVVLYHEVLSAREISMLIGKAAQNMKNTKIHKERAVPKKNRGRTAKGFWLKKESNELTKRITRRIMDMTGFDLADSEGFQVINYGIGGHYFLHMDYFDFASSNHTDTRSRYSIDLGDRIATVLFYLTDVEQGGATVFGDVGYYVSPQAGTAIFWYNLDTDGNGDPRTRHAACPVIVGSKWVMTEWIREKRQIFIRPCLPKAKGTSTKS