lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression.
Subcellular Localization:
Nucleus.
Sequence:
MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAAAAIFPGAVPAARPPYPGAVYAGYAPPSLAAPPPVYYPAASPGPCRVFGLVPERPLSPELGPAPSGPGGSCAFASAGAPATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGSSGGVETTVDFYGRTSPGQFGALGACYNPGGQLGGASAGAYHARHAAAYPGGIDRFVSAM
The following text describes a protein:
Function:
Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRKKLYLLCGVNSERKLIVDLLAILFGIGSWLGINSVYVQLPLLVGNAPEGWNLPSYLVVIIQLGNIGPILYTAALRIKSFRDSYLIIALLVLGSCAAMTTAFVYDQTVHVFGAERSVPLFITVFGLSLVGCTSSVLFMPYMGRFKGIYLITYLIGEGFSGFVPSIVALIQGVGGNGECIAVNGTDPNEPPQYTSYTPPPRFGTRPYFIVSSVILAISMVAFVLLDRLAVCRREYAAVSIGNGNNYAYEPSTPNDEETRSAAGDAATTTKGKASLDRTNYLLMMVLISVMCLFGNGFFPSIQSYSCLPYGNVAYHLTVTLSSMANPAACFLAFFVQRNSIRSIVALSVVFVPFAAYALTTAMTSPDPPLMHNVLGDILVVACWTLLVGLVSYIRLAITTLLRCEGGQTLVWVGVASQLGSLVGSILSFTLVNFTDTFQQYYPC
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA (7SK RNA), leading to stabilize it. Also has a non-enzymatic function as part of the 7SK RNP complex: the 7SK RNP complex sequesters the positive transcription elongation factor b (P-TEFb) in a large inactive 7SK RNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. The 7SK RNP complex also promotes snRNA gene transcription by RNA polymerase II via interaction with the little elongation complex (LEC). In the 7SK RNP complex, MEPCE is required to stabilize 7SK RNA and facilitate the assembly of 7SK RNP complex: it has a non-enzymatic function (By similarity). MEPCE has a non-enzymatic function in the 7SK RNP complex; interaction with LARP7 within the 7SK RNP complex occluding its catalytic center (By similarity). Also required for stability of U6 snRNAs (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MIEMSFDKETVLSCEGQTDPTSQEFNINDTSALHPPGNTTENNLSKDAGSEASLEKSATTDNNASSESAVLGAESSKQSHNGTKPQQQKVNKRRNTMSAGFKHPGYGKRRRRANSESESVLPTNFLLGGNIFDPLNLNSLLDEEVNKALNAETPKSSPLPAKNRDPVEILIPRDITDPLNLNCLSTGDSLLVSPLKSGGGRRRHRNKHHGANTGRVSTEGIGLTESNGCAAVKDDGTSLVSMTNVHLESTIADQTLLDSTLESSNKSSLTSNDNEVKEKTVDCSTAHLTANPTNPPSSRQRKRRRAGSRTENSSSSSEQHNESQGGNSRSGVSDRQQPYPNQWRPQYSNNNQNPQQPKKKFQYGNYNKYYGYRNPGMSEDPRIRVMNPDWFRGKDVLDLGCNTGHLTLFIAKNWRPASIVGLDIDGSLIHAARQNIRHYLSEVQVQHSRRSGENTKADRGEVSGEEKDKDKTSKHSFPVSLRISRGPIAGPPLPETNTHSLPPGDFPANVTFIKGNYVLESDVLLQTQREEYDVILCLSVTKWVHLNWGDAGLKRFFHRVYKHLRPGGLFILEPQPWSSYNKRKKLTEAICKNYHSIRLKPDQFSSFLTTEVGFSSYELIGTSQNYSKGFQRPISLYHKRPSSLK
The following text describes a protein:
Function:
Inhibitor of the DOA4 deubiquitinase involved in the regulation of protein degradation by the proteasome and maintenance of a normal level of free ubiquitin.
Sequence:
MLSIAEIAAKGLDYPYTNNTSFRVWIHVVGTVLREAEIYRDDGDFEKAYLLYTRFADLLLNKMPGHPGLKANRALFKKMTGKMPGVLQEMQQLKKALEVQITEEKKAEEERQRKLRALQQASDSGRSGGSRGSGSTSRIDDLRSQLGQGGPDHVNLEDYSFGRYDTRQVSEPMYEHGNWQQQAHHQHDTFDYPDLNRELSSVLSPYVYESGPLTLSPTAGQIRLADSPPAIPAKPAALKASYEKPAAPAPPTTSSSSVEHTSRYTTEGGLALRSLFIPAELEATFLKVAHANTVKNLETCGILCGKLSRNAFFVTHLMIPPQESTSDTCQTTNEELLFEQIDENDLFVLGWIHTHPTQTCFMSSVDLHTQNSYQIMLPEAVALVCAPQHDPNFGIFRLSDPPGVDIIKNCNRGGFHPHTEDNIYNNARHAMVKNGLPFKMKDLRS
The following text describes a protein:
Function:
Pore-forming toxin with nematicidal activity. In infected C.elegans, induces an increase in intracellular Ca(2+) resulting in necrosis of host intestinal cells. Also, induces the expression of aspartic protease asp-1.
Subcellular Localization:
Secreted. Host cell membrane. Note=Probably secreted as a soluble protein that then inserts into the host membrane and forms pores.
Sequence:
MIIDSKTTLPRHSLIHTIKLNSNKKYGPGDMTNGNQFIISKQEWATIGAYIQTGLGLPVNEQQLRTHVNLSQDISIPSDFSQLYDVYCSDKTSAEWWNKNLYPLIIKSANDIASYGFKVAGDPSIKKDGYFKKLQDELDNIVDNNSDDDAIAKAIKDFKARCGILIKEAKQYEEAAKNIVTSLDQFLHGDQKKLEGVINIQKRLKEVQTALNQAHGESSPAHKELLEKVKNLKTTLERTIKAEQDLEKKVEYSFLLGPLLGFVVYEILENTAVQHIKNQIDEIKKQLDSAQHDLDRDVKIIGMLNSINTDIDNLYSQGQEAIKVFQKLQGIWATIGAQIENLRTTSLQEVQDSDDADEIQIELEDASDAWLVVAQEARDFTLNAYSTNSRQNLPINVISDSCNCSTTNMTSNQYSNPTTNMTSNQYMISHEYTSLPNNFMLSRNSNLEYKCPENNFMIYWYNNSDWYNNSDWYNN
The following text describes a protein:
Function:
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of N-glycans containing Lewis a structures (with the combination of FUT13).
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MKRFYGGLLVVSMCMFLTVYRYVDLNTPVEKPYITAAASVVVTPNTTLPMEWLRITLPDFMKEARNTQEAISGDDIAVVSGLFVEQNVSKEEREPLLTWNRLESLVDNAQSLVNGVDAIKEAGIVWESLVSAVEAKKLVDVNENQTRKGKEELCPQFLSKMNATEADGSSLKLQIPCGLTQGSSITVIGIPDGLVGSFRIDLTGQPLPGEPDPPIIVHYNVRLLGDKSTEDPVIVQNSWTASQDWGAEERCPKFDPDMNKKVDDLDECNKMVGGEINRTSSTSLQSNTSRGVPVAREASKHEKYFPFKQGFLSVATLRVGTEGMQMTVDGKHITSFAFRDTLEPWLVSEIRITGDFRLISILASGLPTSEESEHVVDLEALKSPTLSPLRPLDLVIGVFSTANNFKRRMAVRRTWMQYDDVRSGRVAVRFFVGLHKSPLVNLELWNEARTYGDVQLMPFVDYYSLISWKTLAICIFGTEVDSAKFIMKTDDDAFVRVDEVLLSLSMTNNTRGLIYGLINSDSQPIRNPDSKWYISYEEWPEEKYPPWAHGPGYIVSRDIAESVGKLFKEGNLKMFKLEDVAMGIWIAELTKHGLEPHYENDGRIISDGCKDGYVVAHYQSPAEMTCLWRKYQETKRSLCCREW
The following text describes a protein:
Function:
Non-receptor tyrosine-protein kinase which plays a role in pharynx function by regulating pumping and the orientation of pharyngeal muscle fibers, independently of src-1 and src-2. May phosphorylate and thereby negatively regulate src-1 and src-2 activities.
Sequence:
MSNGNSYNHHHQFPMSIPISCSSHSIQSQSRMNTLNANRDLLSPGNDVIVTRTVSPSFYSHGMPARDNVFRKDDHVRILGNTTDPAWYRARNANQEEGLVHADCVVRINGQAYDNGIVRMRASGCDVAPGAASTTSSTSSHHSTAANHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHYKRDADGLCHRLVTPIICETATFSSNGSSSFGSSSTVDLEDRTSVFRHAGLVISSNDIDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTIRNTV
The following text describes a protein:
Function:
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Sequence:
MSFAGDGEDAAVAGDPVVLEITDTSSSAESVPPSSPRPLPVAVSDLSRFDTLPSPTVAVRADRHRLIESSSYFRALLGGSFSESGREYVQLGCNLEAAVQVLRYLFEPSESCTITHGNFLLLLEGALFLAVESLLVECERWFRTMGSRTSSALVPLDFVIEVWYFAQEHGVTFVQDICPEYLAQNFAFVISRKSFNKIPYDLLCSSIECPHLTVDSEKQLCEAILYWVSENMEPCDRPNSNSVDGHLFLLSKVKICLLPLELATGIKRHWFDFGNNIVCTILNLLKDSLKTLLDAIAGGNLKGYGIRITEYSKNIVLSGCPQITTAFLYISVLPTDLDVSFKRRIVSSYTQVDHQSFILYDELEKAAKTLLFRNVRMVDLSKCPNVHFGAAIDWLKLAFPELRIFRALHCLSFHFDDLIYLLLRCPWIDEIDMTIDTSTITPNQSIVSFSSEVLGKVKQNRRRYYIPCPPYDRQLNSVFSNVSRLTLEGRNDIDDVDLVKISALKNSLSYINIRNCTMLTDDGISNFLMKCTKIHSIVLSYTSFGNRSIQTLCTTNPDHNDGHAHVMAFNMQELHLGGCKGIDAAALSQLMSIINITKFLCLRETSLTDGALCKFVGSSLEYLDVSETMVSMVSLAPVIRRNCNLNCLKTAGCRNLLFERDEVEQISGNKYGNFLQEIGSTCCLEDVEMGWGFCPIQIKDLIPSFSKVRKMTVGLGTTLAENVLHALPVICPFLESLTLRFQVISDSVVRNLLESATNLQVLCLHHCIGSLTSFSFQTKAPTLRVLRLQWVTPWITNDDLKILTDNCNLVELSLSGCKLLDSSSQEIISSGWPNLVLLHLEDCGQVTVQGVSSILNCKALEDVLLRHTGRGIGRSIIDDAIRELPLLRKLALDLCDACEEGYESPNNAEGKMIRAVRMSRCKTLRGSCLELPRGSGGASKPVHKDTVVLEWSSTRLTTTIVKERV
The following text describes a protein:
Function:
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity). Required for nitrogen fixation. Involved in electron transfer to nitrogenase.
Subcellular Localization:
Cellular chromatophore membrane; Multi-pass membrane protein.
Sequence:
MQDFLLVLLSTALVNNVVLVKFLGLCPFMGVSRKTDAAIGMGLATTFVITVASAACWLVEALILEPLDLKFLRILSMILVIAAIVQFIETVMRKVTPDLHKALGIYLPLITTNCAVLGLPLMYIQGHLSLAMSTLSGFGASVGFTLVLVIFAGMRERLAQLSVPAAFAGTPIAFVSAGLLGLAFMGFAGLVHV
The following text describes a protein:
Function:
Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins.
Subcellular Localization:
Nucleus.
Sequence:
MVVVACPNSSLVEAQMDADRSGSCSKYDYASAYSRLRSAARAAGTGVSSVLILSSPDVDSVCATRILTSLLLQDDIAHRIVPVEGYRTLLNTLSTVFAPHDNDNASSSSSSTTDVKSVVFINLGAVLSLPTTFNIPPSCTIHVIDSHRPWNLENLFATSHANDSVWCWDDGEIATKLCRQGGERDAFEKLEFDVDSDSESDSDSHSDSHSDSVSDPEDASDSNDSGSDSARSHDERQRDGSGGKRKRGSHSPLSRRRQRHKQGQRHKPRHRSTSASATRLTNAERHRYRNILTRYYARGESFGMSVSSMLYLLCESLGRADRESLWLAIVGLTSLYLSNNIDLETYETYSAAYASEVIAIEPTSSNAPTEAWSLDLLTNANNNAQEQAARSATATATGAARAQNRAVRSVISKNTKAEDADDRSIRIVGSELRLTLYRHWSLETAMYHTAYVAAKLGIWRERGLSKLRGLMAKMGFSLTAVRQNYTHMPLDLRRSLVRKLEAIAPEYGLTQLTYRGFERSLGFRTAPLGAADVVEGVSALLIGAHGIKIEVDTPGMVFASSSTTPLGNSFGANLNPANPNAQTSELFATKRVWNLGTALTDSITSAIGAATGNAWSNDQTEANGGLHVDVSSTQPALAAVASVQDVGALERAERRVATSNFYEAYRALDFSRSTSVDLLRSSVLLSEALHRKIVARGISLITNQSIRTLKNFRLAILRDGADLELFTHVDVLARLADWLTTSLRDIIVQQQASTNAQRKKQPAASTRLPFILAALHRAKDTFLVLGSTASAIDGVVQHNHFTAAFQHAASVSRARVRHDHFRTCSIHVRTSDLAAFVENVHLKIK
The following text describes a protein:
Function:
Cell-wall hydrolase involved in septum cleavage during cell division.
Subcellular Localization:
Periplasm.
Domain:
LysM domains are thought to be involved in peptidoglycan binding.
Sequence:
MKTKILFFLFFSTFSFSIFAAPITIAIDPGHGGKDPGAISRNLGIYEKNVTLSIAKELKALLDKDPHFRGVLTRKSDYYISVPERSEIARKFKANYLISIHADSSKSPDRRGASVWVLSNRRANDEMGQWLEDDEKRSELLGGAGKVLSHNNDKYLDQTVLDLQFGHSQRTGYVLGEHILHHFAKVTTLSRSTPQHASLGVLRSPDIPSVLVETGFLSNSEEEKKLNSQTYRRRIAYMIYEGLVAFHSGKTNTLVKDNLVQNIKQNDIKKSGKNNRTSEQNINEDNIKDSGIRHIVKKGESLGSLSNKYHVKVSDIIKLNQLKRKTLWLNESIKIPDNVEIKNKSLTIKENDFHKKQNSLVNNTNKDLKKEKNTQTNNQKNIIPLYHKVTKNQTLYAISREYNIPVNILLSLNPHLKNGKVITGQKIKLREK
The following text describes a protein:
Function:
Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity).
Subcellular Localization:
Plastid, chloroplast. Mitochondrion.
Domain:
Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
Sequence:
MGLHKLRLAAAVPVTFSSRLFLKPFTNTLTLGLFSRHLQPRNKPLLVRAFSASAAVQDIPATQTSDSSVAARPLWKAAIDFKWIRDNKEAVEINIRNRNSNANLEAVLQLYENMVNLQKEVERLREERNNVAKKMKGKLEPSERERLVEEGKNLKESLVTLEEDLVKLKDELQHVAQSIPNMTHPDVPVGGEDSSAIRQEVGSPREFSFPIKDHLQLGKDLDLIDFDSAAEVSGSKFFYLKNEAVLLEMALLNWTLSQVMKKGYTPLTTPEIVRSSIVEKCGFQPRGDNTQVYSIDGTDQCLIGTAEIPVGGIHMDSILLESALPLKYIAFSHCFRTEAGAAGAATKGLYRVHQFSKAEMFVICQPEDSESFHQELIQIEEDLFTSLGLHFKTLDMATADLGAPAYRKFDIEAWMPGLGRFGEISSASNCTDYQSRRLGIRYRPSEPPQTGPKKGKANLPATKFVHTLNATACAVPRMMVCLLENYQQEDGSVVIPEPLRPFMGGIELIKPKHK
The following text describes a protein:
Function:
This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. Also, involved in the degradation of oxidized and glycated proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
DKFVAQESWGEREPVHQPVLVVLDIDTGAVRILDVPSNISPGQAIWCRDSSGIVCAGWNNEPWRLGIIYCSSRRNALYYIPVDDSKFEQLTEENYTIYSPRFNPQGTKLVYIRYPSGGPHHNCAALMQIDWNTRERSTLVEEVSKPKNNDFCGIYSMELPKRCWNKDGNKLYFHTIRRVYQDIFEVDTINKKINCITKDNERGCWSVIDVHRNILLASYASPAISDRLMIAAIPSASDHALTSMDWIEFGNSICTVSLNVACTLHFAKKLKLIFLSRLLEFDAIFIKPTAVTSPPLIVVPHGGPHSAFYSYYQIYYYCFCLLGYAVLQVNYRGSMGYGQQGIDSLIGNVGIVDVADVKSAVDYILKNGNINNEKVFIFGGSHGGFLGTHMVGQFPDLFKACAVRNPVTDIASMLNVTDIPDWCYVEAGFKWDFRNLSSSDVYSKMINQSPMNYISQVRTPTLILLGEDDERVPPYQGREFFRALKARGIETRLLSYPGNNHSLSEVECEADVFMNVVNWFSRRQ
The following text describes a protein:
Function:
Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
Sequence:
MSLYTKTCEVCDERISRYRCPRCGVLTCSMACCKLHKNGKNCSGIREKTAYVSMNDFTDLTLLNDYRFLEDAERKIDTASKENKLKGNLRYKPKYFCILQSQARKRGTSLQVLPTAFTRHKCNKSYYDYKKGSIDWTVEWRFNDDDIKPTTSKVSESKILLEAFEEFISEYSSKVPSLENALERYTAALRDDKLKIFFKVERISKNQKNKLHEVDLKRSLMENLKDKTILEFPTFLVTAK
The following text describes a protein:
Function:
Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MVLVWLLLWGTLTSLLEADPQREKCPPPNKIPFAKYTAESYLKGSQLAYRCNKGYIRRQGSEHFIECKNHSGHLEWNTFECFPTFNENGLPTEQPPSTPHEWLADGANDPPKHTDHCRAPPEQKHAKPWENMVNFYPGQKLQYKCNKDYKSQSPLPAESICKRICGKLKWTTLNFKCIHANDSDPSPPLEPGNDHTTEYSTDCPLITTSGPTDTEKMATSTVPVTKPTSTTNILVFFSTLEHQIAGMPGSPLVAVCACMLIMVIFLGWITWRRWGKRSGSGKSKPGKGKLGSASKNGPGISEYEEQTRKLKLHP
The following text describes a protein:
Function:
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.
Sequence:
MGKADRKKSARASASPYQKPSKGDGRSAAAKAGSAIFKFNTDLGQHILKNGAIADNIVDKANVQPSQTVLEVGPGPGILTTRILEKAKKVVAVEFDPRMAAELTKRVQATPMEKKLQIVLGDFIKTDLSKLPPFQVCISNTPYQISSPLIFKLLSMPNPPKMCVLMVQREFALRLLARPGDALYSRLSVNVQFFSKVSHIMKVGRNNFRPPPQVESSVVRIEPKLGKPEISWDEWDGMLRICFVRKNKTLRAGFMATKIRQMIERNWITWAAMHPEKVSQGDVDLLSGKTPFPEGKFANSKDDGDVDMDVDDAGPVVDEDDVGDIFMNGVEGGEKGAAVAQSGPVITVAGQQVPRTSVTRLIQFKIERILDTAGLANHRANKCDENDFLRLLHACNTEGIHFS
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MGGRGRGRGNAVSFNIEQLGFGRGEAGPVSVTQPPPLFPSLENRPLPLIKDVENEYILVTQKDLSTRMRNSPFYLKKSEKINSTSYEKELPVLWNRMPAELRDETFTKRLATGKSKVTLNAKKKKVEDPDKIFAKLEKKERNESEVEEDGDGKEDEDDQDKSDDEKVENEDDVEEDLDEEMDDHTDYANNYFENGEAYLEDEEGQDDGEAQF
The following text describes a protein:
Function:
Involved in DNA recombination.
Sequence:
MSAAESARRTGMNEIIFVAGDWPVRTIDALIGFGVLVLILLVVIAVVIARSGRRGAELAMANAIRADELEERISQMLHAQSEASGRVDAMTQALAGRQAEMARAVNERLDSVTHRVGQSMEHSTRNTMESLHALHERLGIIDNAHKNLTDLTTQVTTLRDVLANKQSRGAFGQARMEAIVQDGLPKGAYEFQFTLSTGKRPDCVVFLPDQRPLCIDAKFPLEAMTALHDARTDEEKRIATQRLRGDVMKHVSDIAEKYLVTGETQEMALMFVPSESVYAEIHDGFDDVIQKAYRARVVLVSPSLLMLAIQVMQQIMKDARMRDAADQIRTEVIKLGDDLGRLRDRVLKLQKHFADVNEDVRQVLISADKIEKRAGRIEELDFSKADAPAEGPHLVATGAAELFPRKLQAGE
The following text describes a protein:
Function:
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MNRILIIAGGTGGHIFPALAVARELREQEVDVQWLGVKGGLEEKLVPDSFPLHLIQIKAFRGKRGLQQLLMPLRLVRAVFQAYRIIRQFKPDVILGMGGYVAGPGGLAAWITRTPLIIHEQNSIPGLTNRVLAKMAKFILQGFPDTFPQNRKVITTGNPVRTELVKMPLPQVRLAARRGPLRILVLGGSQGARSINQKMLAALSSYPRSEEIAVWHQTGQRDFEFIQKEYEKIKIEAKVDNFISDMAGAYGWADLVVCRAGALTVCEIASVGVASIFIPYPHAVDNHQFHNARFLEQAGAAIIISEESLTETDLMRWFEQFAQDRDRLLTMAENARKLAKPEAVQRVIAQCKKFYAAR
The following text describes a protein:
Function:
May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols (By similarity).
Sequence:
MDYKAIAQQTAEQVLAYNQDLSGWKLIKSSKKVTVSSKTSRIFHGNLYRVEGIIPESAAHLSDFLFKHDHRVSWDKSLKGFNVIHKIDSDTLICHTITQSFAMGSISPRDFIDLVHIKHYERNVDIISTKSVDFPGYAPTSTYIRGFNHPSGYVCSPLKENPAYSKLVIFVQTEMKGKLPASVIEKSMPSNLVSFLLNVKDGVKTYRIPPIRARHSSHSSVHKKKEGHSAIKP
The following text describes a protein:
Function:
Transcription repressor subunit of the SEU-SLK1 and SEU-SLK2 transcriptional corepressor of abiotic stress (e.g. salt and osmotic stress) response genes, by means of an epigenetic process involving histone modification (e.g. H3K9 and H3K14 acetylation), probably by recruiting HDAC, to facilitate the condensation of chromatin thus preventing transcription at the target genes. Can also act as a transcription activator. Implicated in embryo and floral development. Involved in post-synthesis cell wall modifications necessary for mucilage extrusion from seeds upon imbibition, probably by promoting the expression of genes required for mucilage maturation (e.g. MUM2). Regulates the maintenance on leaf polarity and meristem activity as well as the initiation of embryonic shoot apical meristem (SAM) development.
Subcellular Localization:
Nucleus.
Sequence:
MAQSNWEADKMLDVYIYDYLVKKKLHNTAKSFMTEGKVSPDPVAIDAPGGFLFEWWSVFWDIFIARTNEKHSEAAAAYIEAQQGKAKEQQMQIQQLQMMRQAQMQRRDPNHPSLGGPMNAIGSEGMIGQSNASALAAKMYEERMKQPNPMNSETSQPHLDARMALLKSATNHHGQIVQGNHQGGVSAALQQIQSRTQQPTEIKTEVNLGTSPRQLPVDPSTVYGQGILQSKPGMGSAGLNPGVSGLPLKGWPLTGIEQMRPGLGGPQVQKSFLQNQSQFQLSPQQQQHQMLAQVQAQGNMTNSPMYGGDMDPRRFTGLPRGNLNPKDGQQNANDGSIGSPMQSSSSKHISMPPVQQSSSQQQDHLLSQQSQQNNRKRKGPSSSGPANSTGTGNTVGPSNSQPSTPSTHTPVDGVAIAGNMHHVNSMPKGPMMYGSDGIGGLASSANQLLQDDMDQFGDVGALEDNVESFLSQDDGDGGSLFGTLKRNSSVHTETSKPFSFNEVSCIRKSASKVICCSFSYDGKLLASAGHDKKVFIWNMETLQVESTPEEHAHIITDVRFRPNSTQLATSSFDKTIKIWDASDPGYFLRTISGHAAPVMSIDFHPKKTELLCSCDSNNDIRFWDINASCVRAVKGASTQVRFQPRTGQFLAAASENTVSIFDIENNNKRVNIFKGHSSNVHSVCWSPNGELVASVSEDAVKLWSLSSGDCIHELSNSGNKFHSVVFHPSYPDLLVIGGYQAIELWNTMENKCMTVAGHECVISALAQSPSTGVVASASHDKSVKIWK
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MVTMPMMMNGDTAKTTASDTNTPPPAAVFHDFLGGKAPTFPGGSLEKQVGSQLERISSYGPKSDLSVSEVSNLFVGSKRSHSDSAFTGSSREGIPQMIPENSHVMKMLRSASGGDRLKISPFDGPLHGVPQHIRPLSSFVSQTTNANFVNSERSNPMNVGGSSMQYNACVMKSSPLMYQGPSSRLRDSSSGPSVLSQLAADEGSRTGNKGSGILNSINAGSNPVSERSPSGIFPSGCNLRPTTRNYESEPSNPPSSRGLITSGSRQMTIIYGGQVHVFDDVHPNKADVIMSLAGSNGGSWSTNLPKTSARTTTNDSCLPSGDHETSIPADWSLAQKYRNLLSAGANSIHGLGSAGGMIAKAAGTSGHLMEPSRETKREV
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MAAASQEKQQQLLPTFGVLRNAAALLDEMQLMGEAQGAKKVINSELWHACAGPLVCLPQRGSLVYYFPQGHSEQVAATTKKTPNSRIPNYPSLPSQLLCQVHNITMHADKDTDEVYAQMTLQPVNSETDVFPIPSLGSYAKSKHPAEYFCKNLTASDTSTHGGFSVPRRAAEKLFPQLDYSMQPPNQELIVRDLHDNMWTFRHIYRGQPKRHLLTTGWSLFVGAKRLKAGDSVLFIRDEKSQLLVGVRRATNQQTALSSSVLSTDSMHIGVLAAAAHAASSGSSFTIYYNPRTSPSPFVVPVARYNKANYIQQSVGMRMAMMFETEESSKRRYTGTIVGVSDSDPMRWPNSKWRNLQIEWDEHGYGERPERVSIWDIETPENTIVFPSASLNSKRQCLPGYGVPGLDIASVNMSPFQRAPGNPYGNLQHMPAVGSELAMMMFLNQSGQNMGTPLSCHQSSYSSIIQNVKQNYMPPSTFGHPIGSIKPESMPSNEAQQQQLHAPKMQRGDSESCEVQPAADSVSASELHVAGREPRNTDKYPSQSISEQNGKGEPRVKPRRSKKGSSRKTISENSELSSAPSRICDDQQHVSEAELVSCDTKHVNCGNNEGSSGALTHGDFAGQLQCQQVEQNELVSPPKLESSISPDGGKSVNSFPNQASFSQFFDGLDWMVQPPNYQDSNGIQSVSASENIFSPSANIGSTINTDTLETFQNSCLSDCFPNSIQDFIGSPDLHSLTFLSPEMQNLDVHHDGSNVPSTSNSYVQMSFSEEDSGNHMESMQRGMNNISSCSQPQTTEGFNLGMYSKLPSLKESQVLSLPEIHNSSRGTSSCSMDAAEYSIGRSAKPMKPPVRTYTKVQKLGSVGRSIDVTRYRDYRELRSAIASMFGLQGKLEHPASSDWKLVYVDYENDVLLVGDDPWEEFINCVRCIRILSPSEVQQMSENGMQVLNDCIQADQ
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MTEKCNVPSINVVNNSTQRKLPHCQYVGVYKRRKFEEKKISIITNKLKRRVLVIGTKEIDLETSILTLDLNENHIEEEDALLCFRIISNKIYILKFDNCEDYVYWMEQIADLATVCGMYGIPLKHAIKKSQWRVPLPIFRAMQYLEEHKGDEYVGIFRMSGGTVEMKKIRTQVDGEKDIDPMDFCDCVLAAAVIKDYLRLLPNPLIPYNLYEEFIELRNNHRGHQFVINLPLENQNTLWYIFSFLRRVLEQQDINKMSIVSIATCITLSISRKPPSSKISDLEHLDYAHESVQYLLENFDEIFHEITTLNEMEGMAPPSYPIIFDGLHSKSSKITSSKKQEKKNFRKSFKLPFSRNSLGINLDLCHSTDVFKCKTDRPTCYTQQVSPRSKLGEVVSTHILSLKKPPISLDFVSENSELASVTGEETKPLDERETKSIGDRVLKKKPFSSSNSPSSSSSTIQTIQTQTSSEIGQESLNEKDDQDDIRSLKKIIALKDKQILELQLQNKILQEKIYQLTSGSTTISSQRSN
The following text describes a protein:
Function:
Regulator of cell cycle G1 phase progression. Ensures the correct sequence of S phase and mitosis in the cell by acting as an inhibitor of the cdc2 mitotic kinase. Probably interacts with cdc2 to inhibit its action until the cell mass for Start is reached. Determines the length of the pre-Start G1 period and prevents mitosis from happening in early G1 cells. Required for maintaining pheromone-induced G1 arrest. Acts as an adapter protein since interaction with cdc13 promotes cyclin proteolysis during G1. Becomes a target for degradation at the G1/S phase transition, following phosphorylation by cig1-associated cdc2 at the G1/S phase transition.
Subcellular Localization:
Nucleus.
Sequence:
MEPSTPPMRGLCTPSTPESPGSFKGVIDASLEGNSSIMIDEIPESDLPAPQVSTFPPTPAKTPKKQLLPNLMLQDRSNSLERCMEEDREHNPFLSSSDNQLLSRKKRKPTPPPSDGLYYVFRGKRIKKSFRPGTDLSTFKPKLLFADSAPSSSSDNPTSSVDLNDYSQIGILPPNLNSIGNKMFSLKSRVPSSSSGSFVAPPPQMRLPAYSSPQKSRSNTKDENRHNLLR
The following text describes a protein:
Function:
Crucial for commitment to meiosis but it is not sufficient itself for the commitment. May be a splicing regulator.
Miscellaneous:
MISCELLANEOUS: The expression of mei2 protein is negatively controlled by cAMP.
Sequence:
MIMETESPLSITSPSPSDSTFQVDMEKTMHALPSSLLDSPLLSTNEHYPPKSTLLLSGPSPIRNIQLSATKSSESNSIDYLTDTQNIFPNFVNNENNYQFSTAPLNPIDACRVGERKVFTTGNVLLSADRQPLSTWQQNISVLSESPPQNGIQSYISSSEQAAQALTRKPSVTGFRSSSLNSNSDDIDIFSHASRYLFVTNLPRIVPYATLLELFSKLGDVKGIDTSSLSTDGICIVAFFDIRQAIQAAKSLRSQRFFNDRLLYFQFCQRSSIQKMINQGATIQFLDDNEGQLLLNMQGGSVLSILQLQSILQTFGPLLIMKPLRSQNVSQIICEFYDTRDASFALDELDGRIIHNCCLQVAYYDAMADSVSTSSASSLSVPRGFSGMLNNNSEWNNSMTMSSNQETPTAASCAVSRIGSSYGMSNNFGSVPLGRTESSPAWGTSGYYDVSSTSPVAPSDRNPSRQYNSIRYGLDVNPIAPPNSSRLKQRNSDLLNGINPQWSPFSSNTGKVFDSPTGSLGMRRSLTVGANASCSNPTNLSFASLTLHDSKADSTLSASSLNPDLNLQRYTPTVEKHASDRNSVDYAQIASGIDTRTTVMIKNIPNKFTQQMLRDYIDVTNKGTYDFLYLRIDFVNKCNVGYAFINFIEPQSIITFGKARVGTQWNVFHSEKICDISYANIQGKDRLIEKFRNSCVMDENPAYRPKIFVSHGPNRGMEEPFPAPNNARRKLRSIASAQQIGLFPPTASKC
The following text describes a protein:
Function:
Scaffold protein component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Pentamerizes into a star-shaped structure and nucleates the assembly of the complex. The pentamer binds a single copy each of PIKFYVE and FIG4 and coordinates both PIKfyve kinase activity and FIG4 phosphatase activity, being required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
Subcellular Localization:
Endomembrane system.
Sequence:
MPNKDLMTIAPNAARGLNDKFYEKRKAAALEIERIVRDLHKQNEHQQVIQLIRQIIHDYVLSHINPNSCRGGVIALAAIVTGIGKEANQYMKDVIPVILRCFDDSDKETRFFACEAMYNIAKVIRDDILMYLNDVFKGLSKLIGDASVRTGAQLLDRLMKDIVTEKSTPVNVVTFIPLLRDRIYTKNPYARQFVVSWISVLQSIPKFDLLAYLPEFLDGLFIILGDSGDELRKMCATILGEFLKEISQRSFSGVAATVKYSDLVHVLMAHCISSDDVTQLTAIVWLQEFVNIDGLSMLAHCADILVAILPLLAYEDSGINQNILLYKRKEKSAGNVDVTATAVVSLPLPDGFLHANTVLNVLIRMLSNVAIRTKLASLEWIYLLSINLEDEMADRMDSLRLVLMETLKDKSDEVKRQILMICIENIILKLQLIFRSLFKNLKDKKDDYFMKFIAELTNEFQHDEQFIKDRGSVIIRQLCSLLNAEDVYMAFARTLLDADNTKFTVLMVRMLNTILMTAHELCSLRQKLNALRDEESYNLFRCLYYSWCHNPVATVSLCFLTQTYKHAFDLIEMFGNFDINVEFLAEIDRLVQLLESPGFTYLRLQLLEIEDNYYLVKALYGLLMLLPQVTAFTTLRQRLECVPVLHSSLRYQSRYRTTVIKLGCILPVN