lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Sequence:
MARLLLGDGRALPAVVVVALLVVVVALVSVATADDGAPYTREALEKLPVEQLIQVLDEWDISCPDCEEPEEFINRIIVTQQIRALPQPVEPVHSTQDHEPGSEKFLAGIQELQSREAELKKQMLEAGLNESNRRYGGIHLSPEQMQQLTDHLKKQHAQPMATPPASPAKRLATEAQSPRRSPRVAAKRSKQLVLEPDSHAEEASELMDAENLFAEALQTEDQAPGTTVETKIEGFERFDGITRQYAQERNRSSEVHGQKWDGRCYFLQMSLLSPFARARTHPGLQRIESDIPERCKIEPCVLGVDEAGRGPVLGPMVYAVAFAPLSENARMKKLGFADSKQLSEAKRDELFKVIKENADWMGWKVHMLAASDISAGMLSRTKHNLNAQAHESTVDLVKRLHAQGVQIKEDLTYRLRLNHRQLYVDTVGKAHIYQQQLENWLRPTIPNIKIVVESKLCVTHRVSDLCVLILDIANADVTYPIVSAASICAKVTRDAVLTYWRHPEQREIDNDFGCGYPGDSSTKAWLRKVLDPIFGFPSLVRFSWSTARDLLLKEGTKIEWEDDGDEDDDEAQNKLSFVKPRHGFFHRRGFKSVVKW
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.
Sequence:
MVTRSVLKFGGSSVSDFTKIKRIAEMLKERVNQDEQLIVVVSAMGNTTDQLMTNVSTLTKAPKQQELALLLTTGEQQTVSYLSMVLNDIGMNAKAMTGYQAGIKTIGHHLKSKIAQINPQTFEQAFQENDILVVAGFQGINEHQELTTLGRGGSDTTAVALAVSNQIPCEIYTDVDGVYATDPRLLPKAKRLDIVSYEEMMEMSALGAGVLETRSVELAKNYNIPLYLGKTLSNVKGTWIMSNEEILEKKAVTGVALDKHMMHVTISYPLPDNQLLTQLFTELEEGAVNVDMISQIVNLDGLQLSFTIKDSDFHQISMILETLKNQYEALAYKINEHYVKISLIGSGMRDMSGVASKAFLTLIENNIPFYQTTTSEISISYVIDDFNGQQAVEKLYDAFNI
The following text describes a protein:
Function:
VirB proteins are suggested to act at the bacterial surface and there play an important role in directing T-DNA transfer to plant cells.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MRCFERYRVHLNRLSLSNAVMRMVSGYAPSVVGAMGWSIFSSGPAAAQSAGGGTDPATMVNNICTFILGPFGQSLAVLGIVAIGISWMFGRASLGLVAGVVGGIVIMFGASFLGKTLTGGG
The following text describes a protein:
Function:
Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MWPRLQTVIQTVRNRVIHLRPLQFRNLKFTQVLNSCSQHVNNLTGYSKIEQLKVAITTHERLLKDKRSLALQARKAYLDAVQKRSNSQREVNELLQRQSSWSPTDLERFTALYRNDHSNKTLESDSQKKMEQAEEQVDEAQDSLVQAILTRYHEEQVWSDKIRRASTWGTWGLMGINLILFVVVQLILEPKKRRRWLHQAMVYIDKENKSQYETQSLQMKKLESMMNTTQHSAPDSTVKTLPHIDEPSEKKNKDVSVSSYNTFTEFVGECPRISFTSWSTFLNTIHQVFNYIFSPDPLVFSQKQFSTYTAECALLGSALTSLLFLLLQNKSS
The following text describes a protein:
Function:
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation.
Miscellaneous:
MISCELLANEOUS: Present with 688 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MDLLGDIVEKDTSDSVESNDNGTLSTNNCGTGFPELYKPKKISSWKERLREKRAQKKKTSGKDAEKQQTSTDAPLSEAKSIHNENIKVLQGMSDEQIVQEREDLYNSLDPKLIAKLLKNINKRAKDENNTPLFAEIEGASGTWVGGNKQGIYDLPPLDDEDVDVALEIRPMLGKDAKHVQFEEAGKEKDVEEEAKTNDDVDDIAPLDFQMAQCIDHMKNEELFKDVHFIKEESQNEINLEKLDINDPNFNDKLHEKYFPDLPKEVDKLKWMQPVQQKTDKNYIIEDVSECRFDFNGDLVPPTRQIDSTIHSGLHHHSDSPELAGYTIVELEHLARSTFPSQRCIAIQTLGRILYKLGQKSYYQLVPEIDADTYKEDGSISNVMDKIYSMFWDLIKDGKVIESLEISSDEKFTRNLSVRNYAIDALWLWKQGGGDFRTKK
The following text describes a protein:
Function:
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MEGVPYAYTTSFKTQSFLSSALSSSSIITIHQKRHKTILKSISRRNLVICASSGSSSVVKLLDYGAGNVRSLRNAIHYLGFEIEDVQTPKDILDAERLIFPGVGAFASAMDVLVKTGMAEALCSYIKNDRPFLGICLGLQLLFESSEENGPVNGLGLIPGVVGRFNSSNGFRVPHIGWNALQITKDSEILDDIGDHHVYFVHSYRAMPSDDNKEWISSTCNYGDDFIASIRRGNVHAVQFHPEKSGGKIFCALNVGLSVLRRFLDPKSQGTKNLTQGKASKLAKRVIACLDVRTNDKGDLVVTKGDQYDVREHTKENEVRNLGKPVELAGQYYKDGADEVSFLNITGFRDFPLGDLPMLQVLRRTSENVFVPLTVGGGIRDFTDANGRHYSSLEVASEYFRSGADKISIGSDAVHAAEEYMKTKVKTGKSSLEQISKVYGNQAVVVSIDPRRVYLKSPNDVQFKTIRVTKPGPSGEEYAWYQCTKSLSYAHPEWLSVPKVNGGREGRPIGAYELAKVVEELGAGEILLNCIDCDGQGKGFDIDLIKLISDAVSIPVIASSGAGAVEHFSEVFMKTNASAALAAGIFHRKEVPIQSVKGHLSKEGIEVRI
The following text describes a protein:
Function:
Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.
Subcellular Localization:
Lysosome membrane; Single-pass type I membrane protein; Lumenal side.
Sequence:
MATAGVSAALCVLFLCLSLQPSRGLFNSGTDGYRRKVSLELNPGLNSSPAAPPGVNVLHVRAVGPSDTLHFIWGSQGAPTLLLIHTNSSNSSLHIDWQRMLSSNSTGSLWVEPETSVQYSSALVFTRIWEYSDDNDTADPSRVPSSSFFPAYDLADFAWDDLNRTLNLATLRGQLCGRNSSDPAGAFANGSVCLEISAFEAWGRDAAWPRLLHSANSSQLRLVVSNVTERANQSRFALEMVAVTGRGRQSRVDTLRSIDDENTPSIFQVSQWVTMPANARAPVLSFAQWKPVAYRSRAPVFEDATPVRHSALLDLPIPPDSGLVRAFFGDQPSPGYQAVALNVSFGITGDPFYNATRYLSWTVLLGLGSPPQDSFSVLVQVIMAVALGMPLLLLLLGGLYVCLGHRNQAPGYAPIN
The following text describes a protein:
Function:
Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate. Dimerization is functionally required and both subunits work cooperatively in transporting substrate.
Subcellular Localization:
Basolateral cell membrane; Multi-pass membrane protein. Cytoplasm.
Sequence:
MPPPVGPPAVPPPDGGWGWAVVGGAFISIGFSYAFPKATTVFFKDIQRIFNASYSQVAWISSIMLAVMYAGGPISSILVNTYGCRPIMILGGFLCAIGMISASFCNNVLELYICIGVIGGLGLAFNLQPALTMIGRYFYKKRPIANGFAMAGSPVFLSTLAPLNQYLINEYGWRGSFLILGGLLLNCCVAGSLMRPLVAPAGSIAPPPVVEVKHAEKEKLTAWQTVNKYLDLSLFKHRGFLIYLSGNVIMFLGFFAPIVFLSPYAKDNGVDEYQAAFLLSILAFVDMFARPSMGLLANSRWVRPRIQYFFSFAVLYNGVCHLLCPLAESYTGMVVYAVFFGFAFGMVSAVLFETLMDLVGAQRFSSAVGLTTIVECCPVLIGPPLAGQHNTTAL
The following text describes a protein:
Function:
Functions in the determination of disk-specific identity, downstream of Hox genes. Overexpression induces ectopic wings with antero-posterior and dorso-ventral axes in the eye field. Overexpression is sufficient for ectopic expression of vg in eye disks.
Subcellular Localization:
Nucleus. Chromosome. Note=Chromatin-associated; colocalizes on polytene chromosomes with Psc.
Domain:
The BAH domain is required for localization to specific sites on polytene chromosomes.
Sequence:
MATFNPGASSSAADVLSATTATATFLVPTTAAVSHPGAHTAHLQLDQFGGFSAATATPLQHHHHQQTNSSYTFVQIKREPCQVSEISSNNCHQQQQQHHQHHQHQVQHQGLSSASMTASSKTMSSSTLTTLVKIEAPSPKVSELEKSTGNSVPIGIAVARKRPQEALVPAINTPATLPLQPPLNKDLNCFGIRVADLGATSCGNLYFTGNGDLMTTGTATAEELALSAAGVNRAPSTFWQYPNALPIESVISMSPATVGLQYSREASRGQVVLLPAGPTALDPFQQAAAAAAFVWPSAYIPQAPAPGGHSAAAAAAAASLQPTPNLSSLPNFIFPSMGGHQALSTTPSYASTLQLYLAAAATATGSSTMCQHSNQQTSTTTTNSTINLSLAAGSGVTQSGNAASSLSSSSSLSASSSRFLSLATGQTGIPSLLSLPPPTGLKEEYPMPLALPPLVPLEAARDKEQALNLMRLPTPPTSATMEPSSLGHATPHHLFQSGAMATPTPALLNLSMHGNGGELPAATPLPAVSDEAALNYKLHAPLTPQTPPRLADIPVSGSTQLLPQMQDVNIQTDTPVCSEDESFPGSAKPQDPAAEAFPPPTHVQPLELTKPSEASHTQPTECHTQTEPSDIPSASQEESAEQTPPEPIETMTQATQADQTSPEDLTGLELLSNISTNSKPLVRVKQEPVEHIEQPAPQPQPVNIMPSEPTLPMPPMLEMEPTSEREPLGGLKLLCALAEQRIQEEVVQGSSLFATPSSRTPTPTSLALGTTAATPPIFEAKSCYAFGQSQGSVFPSSTSSFQMPLSSPGFPSMQGIELPTTSAGIVAELTPVKRKKHKHSKSSGSDSRKSARCSKKSKKKRHHSSSRQQFSAPAEEDLDLQDDQLQSELRNALHAVDPSYAQRFGQEVFSIMDNSMRMRLAKITRQYRKKKRKLDEISKHKKKKKCSKQQLELQQQQASQQAVQPSSALQQPQMTLSSVLGTSSPLRDYKFPKFSSSNLQASSFLRFPDKTHSFPPPPSLQQSQPEPNPLPSSSSPSTSSFVRLEPSALDAAVAIAPTTSSTSTSGSPSTKQVASARKQRKMKASTVGAAGEQTAATEAKRRFSAIDRELQLTSEHLYRDETRVLTDMGGLFYAGVMKPLRPPDVYSITLDGERGNKSHVMSREDILKDTILEVAPKSVESVPVGTRLCAYWSQQYRCLYPGRAIDSEQVVDGTASSATNAATTAPDFVSVEFDDGDSGRIRLQNIRMLLSDYPIAEYNDNPLYSVGKQKRSALRGGESGPGGVTQDHLTVPGCEDSHSHHSLGMSSDNTTSLAATMELFTQRSEKKRLKKSLKKMSKAQNGVSPATATNGGADAAALGDGVSAEDAARKHHKHKKRKKHKKHHRKNGSEEQEQQVVQQDYSAAGQEATEAPSTEMSSATSSRVKVEVKVKTEQLEMEEEESASNLMSEISDEAKGDDLVEHNNSKGSSKIAAFLPERQLWGWYGTAYRKAGVKGRARKQFYKTIKRGKETITVGDSAVFLSTGRPDRPYIGRIESMWETTTGNKVVRVAWFYHPEETTGCPKLKFPGALFESPHEDENDVQTISHRCEVLQFGSYFEKFGADSKQYQSIYDNNDTYYLAGHYNPRLQVLKLQDDIPTLEELQDTNTTTTTTETTTED
The following text describes a protein:
Function:
Major component of the extracellular matrix of cartilage.
Subcellular Localization:
Secreted.
Sequence:
MKGPFCWPLPLLLLFLQSWETQLQPAGPRCYTGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLHSLDVGLNATRVGVIQYSSQVQSVFPLGAFSNREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAELEHGCQHLCVNAPGTFYCACNSGYKLAPDNRNCLAIDLCAEGTHGCEHLCVSSVDSYFCRCRAGFALQQDQRSCRAIDYCSFGNHSCQHECVSTLVGPQCRCREGHDLLPDGRSCQVRDFCNGVDHGCEFQCVSEGLSFHCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEVQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYSPDFNTMTHLLENLKGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTQNLARLTERLEELENQLASRK
The following text describes a protein:
Function:
Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
Subcellular Localization:
Cytoplasm.
Sequence:
MNDTIAAVSTSSGAGAIGIIRMSGPEALTISSSFLFSKNKFLSPSEILPRTAIQCVFQIGDRKIDQILFFYFKSPNSYTGEDLCEFHFHGNPILLREALDAIFRAGARPAKQGEFSRRAFLNEKLDLTEVEAIGRLISARSRFELELAQKNVFGEVTRFTSNLRSQLISLKAECEAEIDFSTEDLTYESLEERKTRIENVKSLCQTLISKSSSAEKLIQQFRIVLYGEPNTGKSSLMNVLLGKERSIISEIPGTTRDYISEEILLEGIPVRLVDTAGVRETTDHIEKLGIERSEKEFQSADIRLFLVDVSKKENWKEFINKSRERLEGSILIANKIDILNSSWDRNLFSDVKDLIVLEISCKTKEGISNLLDAIKERTGKLGHSEDYVLLEERQRYHFETIVRCLDKTLHLLKEGAPAEIYIQEINYALAEIGEVNGKVDTEEVLGRIFSKFCVGK
The following text describes a protein:
Function:
May play a role in apoptosis. May act as a tumor suppressor.
Sequence:
MGSVSSRSHRVEAQVVMMGLDSAGKTTLLYKLKGHQLVDTLPTVGFNVEPLEAPGQACLTLWDVGGQSPLRASWKDYLEGTAVLVFVLDSTDEARLPEAVAELTEVLEDPHLDGVPLLVLANKHEAPHALPLPEIRNRLGLQRFPGLCWQLRACSALTGEGLPEALGSLRRLLSYRSPRSLQAQGVPSRCWGTQDEDSEGRKQEKARLLSK
The following text describes a protein:
Function:
Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP).
Subcellular Localization:
Cytoplasm. Nucleus. Golgi apparatus membrane. Note=Concentrated at the budding structures localized at the tips of cisternae.
Domain:
The Elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV].
Sequence:
MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVVDESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEETVNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISESSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIVNSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESHDHSFGPMPISANGSNLYDAVRMGAGSSIIENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQSLS
The following text describes a protein:
Function:
Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MESESESGAAADTPPLETLSFHGDEEIIEVVELDPGPPDPADDLAQEMEDVDFEEEEEEEGNEEGWVLEPQEGVVGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSGDHKAKVFCVQRPDR
The following text describes a protein:
Function:
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (By similarity). CCN1-mediated gene regulation is dependent on heparin-binding (By similarity). Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (By similarity). Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3 (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MSSSTFRTLAVAVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVSGQCCEEWVCDEDSIKDSLDDQDDLLGLDASEVELTRNNELIAIGKGSSLKRLPVFGTEPRVLFNPLHAHGQKCIVQTTSWSQCSKSCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCSSVKKYRPKYCGSCVDGRCCTPLQTRTVKMRFRCEDGEMFSKNVMMIQSCKCNYNCPHPNEASFRLYSLFNDIHKFRD
The following text describes a protein:
Function:
Plays essential roles in DNA replication by removing the RNA primers from lagging strand fragments. Exhibits 5'to 3' exonuclease activity on either RNA/DNA or DNA/DNA duplexes and endonuclease activity on either flap or fork DNA structures.
Sequence:
MDLEMMLDEDYKEGICLIDFSQIALSTALVNFPDKEKINLSMVRHLILNSIKFNVKKAKTLGYTKIVLCIDNAKSGYWRRDFAYYYKKNRGKAREESTWDWEGYFESSHKVIDELKAYMPYIVMDIDKYEADDHIAVLVKKFSLEGHKILIISSDGDFTQLHKYPNVKQWSPMHKKWVKIKSGSAEIDCMTKILKGDKKDNVASVKVRSDFWFTRVEGERTPSMKTSIVEAIANDREQAKVLLTESEYNRYKENLVLIDFDYIPDNIASNIVNYYNSYKLPPRGKIYSYFVKAGLSKLTNSINEF
The following text describes a protein:
Function:
Catalyzes the four-electron oxidation of hydrazine to N2. The electrons derived from hydrazine oxidation may be transferred to the quinone pool and exploited to promote the generation of proton-motive force (pmf) across the anammoxosome membrane. Is involved in anaerobic ammonium oxidation (anammox), a biological process in which nitrite is used as the electron acceptor in the conversion of ammonium to dinitrogen gas (N2) and water; this bacterial process has a major role in the Earth's nitrogen cycle and has been estimated to synthesize up to 50% of the dinitrogen gas emitted into our atmosphere from the oceans. Cannot oxidize hydroxylamine to NO.
Subcellular Localization:
Anammoxosome.
Sequence:
MRKFLKVTLASALIGCGVIGTVSSLMVKEAKAVEIITHWVPHEVYGMPGEPDNSGKVFFSGLKAKYMGYPKDAQRSPYPGKYSKFWKTLPAYRYYIPDYMYNRDEVRPSNPIKGTFKLEQCVACHSVMTPGIVRDYNKSAHSKAEPAPTGCDTCHGNNHQKLTMPSSKACGTAECHETQYNEQGQGGIGSHASCSSFAQVECAWSIERPPGDTAGCTFCHTSPEERCSTCHQRHQFDPAVARRSEQCKTCHWGKDHRDWEAYDIGLHGTVYQVNKWDTEQFDFSKKLSDADYVGPTCQYCHMRGGHHNVQRASIVYTSMGMSMADRGAPLWKEKRDRWVSICDDCHSPRFARENLQAMDESVKDASLKYRETFKVAEDLLIDGVLDPMPKDLCPDWSGQHIWSLKIGAYHDGEAYGGTTGESGEFRMSNCTDVERLCFESVGYFQTYIYKGMAHGSWNDATYSDGSFGMDRWLVNVKQNASRARRLAALEKKVGISWQPEQFWKTGEWLDQLTGPYIVKNHPGKTIFDLCPDPGWLDTHHAPAEEVEYIERKLKELGITAGSHSAHHHESGHDPAARSMKEH
The following text describes a protein:
Function:
Protects cells against oxidative stress by converting superoxide radicals to hydrogen peroxide. Oxidative stress is involved in various biological dysfunctions and senescence.
Subcellular Localization:
[Isoform 1]: Secreted, extracellular space; [Isoform 2]: Membrane; Peripheral membrane protein.
Sequence:
MKTRVVLILALSVCIEAASEVIRARAYIFKAEAGKIPTELIGTIDFDQSGSFLKLNGSVSGLAAGKHGFHIHEKGDTGNGCLSAGGHYNPHKLSHGAPDDSNRHIGDLGNIESPASGDTLISVSDSLASLSGQYSIIGRSVVIHEKTDDLGRGTSDQSKTTGNAGSRLACGTIGTVEERILETTTASLPPVTQSQPIGSSSYYYSTFYLPIILYFLLSRIL
The following text describes a protein:
Function:
Involved in RNA editing events in chloroplasts. Required for the editing of a single site in ndhB and ndhF transcripts, which are two plastid-encoded subunits of the chloroplast NAD(P)H dehydrogenase (NDH) complex. Required for the editing of a single site in psbZ. Required for optimal activity of the NDH complex of the photosynthetic electron transport chain.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MSCPLAFTFSLPSIFPFPSQLLPFSRHKHPYLLRATPTSATEDVASAVSGAPSIFISQSRSPEWWIDLLRSKVRSNLLREAVLTYVDMIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKGELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSEKLSGYLETLWERMRKEGYVPDTSCVLHNVEEDEKEILLCGHSEKLAIAFGILNTSPGTIIRVAKNLRVCNDCHLATKFISKIVDREIILRDVRRFHRFKNGTCSCGDYW
The following text describes a protein:
Function:
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MASIRRPHSPAKAQHLLRHHHPFSTASPPSSPLRHASSASSSSSPRKSGYPHPFLFFTRRPLPRFAAFFLLGSFIGLLHFLSHLPLHPHLPAHPSSSHLNHLQQQQQQEQGQPITQQRLPDAAGSNAEEHSGQGKLLIVVTPTRARASQAYYLSRMGQTLRLVRPPVLWVVVEAGKPTPEAALALRRTAVMHRYVGCCDALNASASPAVDFRPHQLNAGLEVVENHRLDGVVYFADEEGVYSLPLFDRLRQIRRFGTWPVPTISDGGHGVVLEGPVCKQNQVVGWHTSGDANKLQRFHVAMSGFAFNSTMLWDPRLRSHKAWNSIRHPEMVEQGFQGTTFVEQLVEDESQMEGIPADCSQIMNWHVPFGSESPVYPKGWRSAANLDVIIPLK
The following text describes a protein:
Function:
Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes.
Subcellular Localization:
Nucleus.
Domain:
Binds DNA via the 2 GATA-type zinc fingers.
Sequence:
MEVSTDQPRWVSHHHPAVLNGQHPDSHHPTLGHTYMDPTQYPLAEEVDVLFNIDGQGNPVPPYYGNSVRATVQRYPTAHHGSQVCRPPLLHGSLPWLDGSKALSSHHSASPWNLSPFSKTSIHHSSPGPLSVYPPASSSTLSAGHSSPHLFTFPPTPPKDVSPDPSISTPGSTGSTRQDEKECIKYQVSLADTMKLESSHSRSSMASLGGATSSAHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDNLEDFPKSSSFNPAALSRHMSSISHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG
The following text describes a protein:
Function:
Probable carboxypeptidase.
Subcellular Localization:
Secreted.
Sequence:
MGEEEASKGEDTVEEIRRMSGYGGDVIAVGGFPTSDSESDSDLAAAEIMIIWAIQGPTSFAPNTLVSQSSLELRLDACGHSLSILQSPCSLNTPGVTGSVMWDSGVVLGKFLEHSVDSKDLSLEGKKIVELGSGCGLVGCVAALLGGNVVLTDLPDRLRLLKKNIDTNLQRGNTRGSAVVQELVWGDDPDPDLIEPFPDYVLCSDVIYSEEAVHHLIQTLVQLCGNQTTIFLSGELRNGPLTMKLEEYNGTLPSLVSTTYSWTKTTSIIFLDQPVGTGFSYSRTQLVDKPSDSGEAKRVHEFLQKWLGKHEEFISNPLYVGGDSYSGKVVPALVQEISKEEKHDVCMYDTGNYQCCKPPINLQGYVLGNPLTEFETDMNSRIPFAHGMALISDELYESLKIICKGKYVNVDPSNTECLKLVEEYNKTSSIIYLDQPVGTGFSFSTQHVDTPSDSGEARRIHEFLQKWLAKHEEFIPNPFYVGGHSYTGKIVPPLVQEISKGNYQRHKPTINLQFTKTVNPFLISEPSCETETPDCYESIGRWVRCNFDIPYTHDIINSVPYHVDNSINGYRSLIFSGDHDLGVPYLGTQAWIRSLNYSVIDDWRPWMINNKPAGCTTTYANKMTFVTIKASGHTAEFKPEESSVMFQRWISGQPL
The following text describes a protein:
Function:
Possesses sialyltransferase-like activity in vitro. Transfers sialic acid to the glycoprotein asialofetuin. The transferred sialic acid is linked to galactose of Gal-beta-1,3-GalNAc through alpha-2,6-linkage.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MKRRHWSHPSCGLLLLVAVFCLLLVFRCSQLRHSGDGAAAAAPDGGAGRNDGDDVDERLVELAAVDPAAMAVLQAAKRLLEGNLARAPERHRDVALRGLREWVGKQERFDPGVMSELVELIKRPIDRYNGDGGGGGEGEGRRYASCAVVGNSGILLAAEHGELIDGHELVVRLNNAPAGDGRYARHVGARTGLAFLNSNVLSQCAVPRRGACFCRAYGEGVPILTYMCNAAHFVEHAVCNNASSSSSGAADATAAAPVIVTDPRLDALCARIVKYYSLRRFARETGRPAEEWARRHEEGMFHYSSGMQAVVAAAGVCDRVSVFGFGKDASARHHYHTLQRRELDLHDYEAEYEFYRDLESRPEAIPFLRQRNSGFRLPPVSFYR
The following text describes a protein:
Function:
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.
Subcellular Localization:
Nucleus.
Sequence:
MSPTKRYSNDVDCELAKRSIWLVKVPRYLSELWDANEGNVVGKLQIGAQVELHTAKGLIHPKPKEPTEGSSSTVTQPEASEIPTEYSFILHDVKSQTMSVLSEDKQGLGADAPIKTGKLAIEGRIIKKAECRPPATSKYMKMKLAHIVKNTQPKKTVKMIEKAAVKFKPVSVHAEDMIKSKQKKDGAKTYRADRDVLRGALFKAFEKHSFYRLQDLQQLLQQPVSYVKEVLQEIAVYNTAPPHKSLWCLKPEYCNYKVNAQSE
The following text describes a protein:
Function:
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
Miscellaneous:
MISCELLANEOUS: Two forms of the protein exist; they have the same N-terminal sequence and approximately the same molecular weight.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MATTAPNLHSLSSSFAFSNPSSNVSATSFTFQIPNKKAQISCISSKKLHTQKSFNFHDAVTPMNKPSFGRDLMVAQATEAVAPTTEEAATSQPKTSKKAKKLKYPRRILDVYQILQSPIITEAAIKNIADENSLLFTVDVRADKKMIREAISNFFGVKVRKVNTLIRPDGTKKAYIMLNKEYNASELAKKIGIFPGGN
The following text describes a protein:
Function:
Putative oxidoreductase.
Sequence:
MKLKSIITEIFEVIAPFFFSFLIIIFSPILKFICFKKSLKFSKPKSIVITGTCSGLGRELACKYSSIYKNDLTLLLMGMNEDNLNQVKQICQNHGSIVYTIIENIKNKERMKNHLIEFHSKHPIDLLIANAGTIESQLKESLSFEDKLREISDTNINGMLNTVLPVIPLMESRGCGQIAIVSSLSKNFSSFYVGYSASKAYISTFTKILRNRLHALNIGVYLIEPGYISTPLTQTLKIKPLFEIKIEDAAPEIIEGIENGKSYISFPFSARCVSIISHAVPEFLTDAINSFNSFFFGRFDFHKKDIKNKIN
The following text describes a protein:
Function:
Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
Subcellular Localization:
Nucleus membrane; Multi-pass membrane protein. Nucleus, nuclear pore complex.
Sequence:
MATASAAVSAPAPPAAPPPSAPGLGSSRCPANAERDLLCRVLGWRIVNSIIWSVLLLPVCTMAFVIFSSLNILHPIQWISDAFHDLYGSCVIFYLLLLSMVIVVISVFNVEFYTVVPSIPCSRLALLGKIVHPQQVMHSLVHSAMGMLMVWCAAVMTKEQYHVLAVPCTDSSSLDSKAAQACLNERHLFLLLSGAFMGYSYSLLYFVNNMNYLPFPIIQQYKLLRFRRVLPLLLRHSAVESLYLVRNFCGFYYFLGYIPKAWISTAMDLHKDEKQHPLDSLAGLLDLSLLYHVWLCGVFLLITWYITWVLFKIHATEAHVFPVQPMFTGDLEECLPRVLSANSPLITKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPHNWVAISRECLALLNDLTQKLVMYQEAAAANGRVKTLASPVDSNKPTLVEEEIAFQTPKSSVMSKTLMPSLSKASLFSPKFASPDASNTAGSPFSTNVANRVVGVLDLNSAMYEASQSPYLRRRGPRLWTALTDLQGNEPSQSPSLALSPVHRVATHRGRGQPNMLYLWLQNKLEQMKSFLSRRVLIVYFFSKHPEASIQALFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILSTLLTLQEAVDKHFKLPHASSRPPRTSGSFMDTSYKTLRFALRASLKTAIYRITTTFGEHLNAVQASAEHQKRLQQFLEFKE
The following text describes a protein:
Function:
Transcriptional regulator involved in the regulation of the entire oxidative D-xylose degradation pathway via repression of the corresponding genes.
Sequence:
MDATSKRLTRTTVASQVRDFIVMEIAQGRLPLGAPVREMEIAAQLGTSQTPVREAFRELAALGLLESRIHVGTRVRQLAEKDLVEAVPIRSALEGIAGRLAANNYHKHAEEVRGSFEAMKEVAEGGDRRVFAAASTTFHRSVVRAAENASLLRAWNALGIEVMTILAMASSDIPLDDAAESHRPIVDALEAGDPELAEHALTHHVAAYLPATAHSNGGVDAAVQAS
The following text describes a protein:
Function:
Inhibits host immune defense by binding to host TNF and various chemokines in the extracellular space. Binds host CC chemokines (beta chemokines) and CXC chemokines (alpha chemokines).
Subcellular Localization:
Secreted.
Domain:
The N-terminal region is similar to host TNF receptor 2/TNFRSF1B and binds host TNF. The C-terminal region is called smallpox virus-encoded chemokine receptor (SECRET), and binds host cytokines.
Sequence:
MKSVLYLYILFLSCIIINGRDAAPYTPPNGKCKDTEYKRHNLCCLSCPPGTYASRLCDSKTNTQCTPCGSGTFTSRNNHLPACLSCNGRCNSNQVETRSCNTTHNRICECSPGYYCLLKGSSGCKACVSQTKCGIGYGVSGHTSVGDVICSPCGFGTYSHTVSSADKCEPVPNNTFNYIDVEITLYPVNDTSCTRTTTTGLSESILTSELTITMNHTDCNPVFREEYFSVLNKVATSGFFTGENRYQNISKVCTLNFEIKCNNKGSSFKQLTKAKNDDGMMSHSETVTLAGDCLSSVDIYILYSNTNAQDYETDTISYRVGNVLDDDSHMPGSCNIHKPITNSKPTRFL