lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalytic subunit of the alternative triglyceride biosynthesis pathway, which mediates formation of triacylglycerol from diacylglycerol and membrane phospholipids. Synthesizes triacylglycerol at the expense of membrane phospholipids, such as phosphatidylcholine (PC) and its ether-linked form (ePC), thereby altering the composition of membranes. The alternative triglyceride biosynthesis pathway is probably required to provide the energy required for rapid growth when fuel sources are limiting. It maintains mitochondrial function during periods of extracellular lipid starvation (By similarity). Can also use acyl-CoA as donor: acts as a acyl-CoA:monoacylglycerol acyltransferase (MGAT), but also shows acyl-CoA:diacylglycerol acyltransferase (DGAT) activity (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MIGSNESSTEGPIPTSYLSFLAYLLGEWTGVEHTEDYLSYGAYLSWVLFPLAIVFILPVAIFFFCFNTSLLLLHIYKRRKNGFNEGHSGDVWYGAKEMLVNLWDGHGRVWHGYELHGDENIPEVPALIVFYHGASPVDYLYFMARLLIRRKRYCHVVADHFVFRLPGLKMFIEVLGVMHGPKEVCVSALKKGYLLAISPGGVREALFSDETYAIMWGNRKGFAQVAIDAKVPIIPMFTQNVREGIRTLGGIKIFRKLYERIRLPIVPMYGWFPVKFRTFIGEPIPYDPNITAEELTAKTKAALQALITKHQKIPGNILRALMERFQTRQKED
The following text describes a protein:
Function:
Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. May recruit the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. Contributes to the repression of target genes of the Wnt signaling pathway and to the methylation-dependent repression of zygotic transcription prior to the mid-blastula transition (MBT). Also required for gastrulation movements.
Subcellular Localization:
Nucleus.
Sequence:
METKKLITATDTQYSGILLNALNDQRIQGLYCDVTVIVEDRKFRAHRNILSACSTYFHQLFSVAGQVVELNFVKADIFAEILNYIYSSKIVRVRCDMLEELIKSGKLLGVPFIAELGIPLSQVKSISGAGGKDGGTDAPSNPDHKAPEPQKSSDSPLPCTVKIKADVKTEMPVITESFSLSSDDYKDKKASGSQDHNSEKEDDDDDVIFCSEIVSSKQAPAERKEAAQTQIPPDNEQVPEVKKVTPSSQVQLTQNSLPTNQQSSKNTSSTTQKFTPPVNANISKNPTPAANGFLSPTAQKQGTPNAVQNQHSQNITSGNALPQQKPVVNFSSIKPQQISAIKPKTEVIIHGNGLSPPSSSVIPLGQQPVTPKHISFDGVQKKQVVTFTQGSPSKPGEFKIKIADVVSGSSLDSFKDSEPRRIIDGKKIITLDTASEIEGLSTGCKVYANIGEDTYDIVIPIKEDPEEGEAKLDLDGLPNRKRMKLKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNVHSWEKKYPCRYCERVFPLAEYRTKHEIHHTGERRYQCLTCGSSFINYQVMASHIRSVHSLDPSGDSKLYRLNPCKTLQIRQYAYVNNSTNGTVINDGAINVPVITDGGINVPVINDGGIVYDIDPDEPQQPASEGNHANSATKPVNWDNIFIQQSNQNMFKLNTSEGGTEFEFVIPESY
The following text describes a protein:
Function:
Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for the maintenance of touch receptor neurons and possibly other type of neurons involved in locomotion.
Sequence:
MEIAFDLSTIFTDNIQRLTRTDLLKYGPKRYWAVAQSIDCLGEMSSKFHGWKRVITMYDKIVDHDEEQTTYIMWEKVNGSKSILKGLLRVGYKTLYLTDNEQNQYMEKAMCILDFFVVPTEQRSGNGFKMFDEMLKAENVTVDQCAFDKPSAALQQFLEKYYDRKDLVWQSNKYALCSNFFIGRHPTVPFTPRQTKRASRASSAVSSHASSRNTSPIGRNRPRHDSVADLMRQDMLAGVRAEVDPNSPTGLKNARDFGHRRIW
The following text describes a protein:
Function:
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Sequence:
MAVVSLDSDLLIATINEFYTTTDEHRRHEIDAILCRFKTDYECMQTVGACMRIISQPTSSSIVRYFGAVALYDVIRVRSEECIANEAVQLSLKTFLIDSLKSGAYAQTTSVLNKLSAALALFSLYCVPDLWPTPVQDLTPTLAGSPEILLKVLSDMAAEFSHVTMPLTQRSKLKGELHKFSENIISVLAVVLRGGDTSSITKQAAVECVEQWLRLPGMALDQWTHVLSDVLGAVVQDCTALASILDIIAENDEFHRNSTLIISICQYICFNVSGKIEEELGADASSEEIATLVAATCSVSENSVPTLVECAAQGGDSELVIRLSQVMQVLANMQGQYPLEEIVSDLPSIYFITLRTEIMQTINSGIQIDKQILSQIGQIYAKILEMSIKKLAFPSKEIWLSWNLEEREQFESYRKTRSEASYDSYHFSAAGTLDFLNQTLEQALGAGDVNRTESCIFQWECVADYLGETDYTAILKCLEMCASSQLSAPPPSTSSSSSDKIDIDLNRRGETLMRLFYSLSHLIQEHEQAKELECALIPIILTYVSTRIPSVRQAIDTLQKFSEDRPESLDIIGEQISTTCYEFFNSSNARDSDRLAALKCIGYVLSRRKPSETMKIIGQILSQQNINEPGIDDQTRHRRYAFQINTFSALFASLTNKKDSNSTSLGENDEEPTIVQLLCEAIPVFETLCSGGSGLDGSNSGSLIQEVCKAVRSALTSLPEHYLPSFFPFIVSLLNSSLFVTESVIAACALAKSTVLQCGSLVGVDMANAFAQWILAFEQHVESPQVDEYLQLIYQVVRKNWKMIRKFPDPSMAAFQSSLKICSFIILNSSVPTEVRSASQILAALATYATSHDDVAMKSTFAENGPILIRAVFRRVQGELMRPTVEALADILLFYFKEFTTDTRTLISGEPYGTSALVTSMFREIGNPRNFKQQTIRFNLAALRDPGSI
The following text describes a protein:
Function:
Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4 (By similarity). Important regulator of the cerebral cortex formation, functions in cerebral cortical neuroprogenitor cells to maintain proliferation and to block differentiation into neurons. Must be down-regulated in order for such cells to exit the cycle and differentiate (By similarity). Participates in the pathways by which SHH promotes cerebellar granule neuron progenitor cells proliferation. Critical for survival of mature olfactory sensory neurons (OSN), directs expression of OSN-specific genes (By similarity). May be involved in osteogenic differentiation. Promotes cell proliferation and survival by inducing the expression of EGR1 sinergistically with ELK1. Once acetylated by EP300, binds to ARE sequences on target genes promoters, such as BCL2 and EGR1 (By similarity). Plays an anti-apoptotic role through the transcriptional regulation of BCL2, this function seems to be cell type-dependent (By similarity). Cooperates with NR1I3/CAR in the transcriptional activation of CYP2B6 in liver. In hepatic cells, represses CRE-dependent transcription and inhibits proliferation by blocking at G2/M phase. May act as a negative regulator of IL1B transduction pathway in liver. Upon IL1B stimulus, cooperates with NLK to activate the transactivation activity of C/EBP subfamily members. Besides its function of transcription factor, acts as a cofactor of CEBPB to activate CEBPA and promote adipocyte differentiation. Regulates centrosome dynamics in a cell-cycle- and centriole-age-dependent manner. Forms 9-foci symmetrical ring scaffold around the mother centriole to control centrosome function and the interaction between centrioles and pericentriolar material (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis, translocates from the centrosome to the midbody.
Sequence:
MSLLATLGLELDRALLPASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTERVDFTALLPLEAPLPPGTLPPPSPAPPDLEAMASLLKKELEQMEDFFLDAPLLPPPSPPPPPPPAPSLPLPLPLPTFDLPQPPTLDTLDLLAVYCRSEAGPGDSGLTTLPVPQQPPPLAPLPSLSRPAPYPSPASTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRSA
The following text describes a protein:
Function:
Antibacterial peptide with narrow spectrum of activity. Inhibits the formation of NO by neuronal nitric oxide synthase.
Subcellular Localization:
Secreted.
Sequence:
GLWQKIKDKASELVSGIVEGVK
The following text describes a protein:
Function:
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleaves pre-rRNA sequences (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSVERIKRAPAFRKGIIIRRKTHLIAMIRRMRKKLDIDGSILYQATGMAIPHLVELSDKYKRQGYNISMDTATVEFMDEIVDEVSIQNKNRLGNVLLLRVSR
The following text describes a protein:
Function:
Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor tsr/cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Required for axon growth.
Miscellaneous:
MISCELLANEOUS: Tyrosine phosphatase activity has not been demonstrated for this protein to date.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MALVTVQRSPSVAGSCSNSDGESEDDEGNSKGNDRSECFFAGKGTALVLALKDIPPLTQSERRLSTDSTRSSNSTQSNNSDIQLHLQSMFYLLQREDTLKMAVKLESQRSNRTRYLVIASRSCCRSGTSDRRRHRIMRHHSVKVGGSAGTKSSTSPAVPTQRQLSVEQTATEASSKCDKTADKENATAAGDNKNTSGMEESCLLGIDCNERTTIGLVVPILADTTIHLDGDGGFSVKVYEKTHIFKPVSVQAMWSALQTLHKVSKKARENNFYASGPSHDWLSSYERRIESDQSCLNEWNAMDALESRRPPSPDAIRNKPPEKEETESVIKMKLKAIMMSVDLDEVTSKYIRGRLEEILDMDLGEYKSFIDAEMLVILGQMDAPTKIFEHVYLGSEWNASNLEELQKNGVRHILNVTREIDNFFPGTFEYFNVRVYDDEKTNLLKYWDDTFRYITRAKAEGSKVLVHCKMGVSRSASVVIAYAMKAYQWEFQQALEHVKKRRSCIKPNKNFLNQLETYSGMLDAMKNKEKLQRSKSETNLKSTKDARLLPGSEPTPLIQALNQAKSKSTGEAGVTPDGEEEDGSRMHRRSIAQKSQRRMVRRSSSTSPKTQTAVVTKQQSQSMENLTPERSVAEEPKNMRFPGSNGENYSVTQNQVLHIQKHTPLSVRTRIHDLEAHRADQLPQQPVWTSLTKLITQTSHLGKSVSGSSSGNIDSRRDSSCSDVFSSQVDSVFAKDEGEKRQRRKTHSWTESLGPSGGIVLDPTPQQQKQQSNAILRPRGTRQRELPSRHASWGSGDNRCCLPQRTSSGSYYDSNRNTTAIFEGVIQDLKRSSNCNVIEGVAVAVEPIVGVGEGTVKRTKQKLEESTSLKKRCQEESQELLLEAVDAGQRRCPSLYRSASSAHSPRQRQPLRCNSEELMHTSDIENKNTTPGDHEATVVLRVQGQTLADDQRISGNVQILKQNFEAKAGVVGTGGGGGGGTAAGSGSSSTIATSVSAVAGACSANPGKKTTSHQSLPSSPVAQHANHVSAASNSNSSASNSSDSS
The following text describes a protein:
Function:
Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MGWFWADTTTSAPAASIAPHPMPRGNAEPPPSCPMHKKASPPAKSEVPKGACPYVPPENASSSSDDAPEKQGLLSRLNPLNNMFSELDNSKASIQTQDLPLSREQSTIPKGDGSLWEYPSPQQMYNAMLRKGYTDTPVDAVESMVSVHNFLNEGAWAEIMGWERRFSKGIAEGYRVCKQGEERANHILGTAENPFDTTTWDDADIPPPKLLRFTGRPTEPTPKSQILQWAGWAMPEKFGTAPPFDRHDWFVERCNSKGCKEVRYVIDYYEGDPEPTGEPVFFLDVRPAVDGPTSAAERMVRWGTDVFWRASGGEARIMKKVQEAREAAAEEASSRGRQYN
The following text describes a protein:
Function:
Plays an essential role in autophagy.
Subcellular Localization:
Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Sequence:
MTVLGPPRSWSCQWLPFLILLLGRGQEPRVEGVTHYKTGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTLIHMTVGGFLPFRYPPFRPWPSLRFLAFLSPVP
The following text describes a protein:
Function:
Binds mRNA, facilitating recognition of most mRNAs by the 30S ribosomal subunit during translation initiation (By similarity). Probably plays a role in trans-translation; binds tmRNA (the product of the ssrA gene). In trans-translation Ala-aminoacylated transfer-messenger RNA (tmRNA, product of the ssrA gene; the 2 termini fold to resemble tRNA(Ala) while it encodes a short internal open reading frame (the tag peptide)) acts like a tRNA, entering the A-site of the ribosome and displacing the stalled mRNA (which is subsequently degraded). The ribosome then switches to translate the ORF on the tmRNA, the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and thus targeted for degradation (By similarity); Binds pyrazinoic acid (POA), the active form of the prodrug pyrazinamide (PZA); POA disrupts tmRNA binding (at 50 ug/ml in vitro) and also trans-translation (at 25 ug/ml in vitro using purified H37Ra ribosomes).
Miscellaneous:
MISCELLANEOUS: Mutations in this gene that alter POA binding may cause antibiotic resistance.
Domain:
Full-length S1 protein and the C-terminal domain (residues 285-481) bind tmRNA; the interaction is disrupted in a concentration-dependent manner by POA. 2 POA molecules bind to the C-terminal domain (residues 285-481) and S1 motif 4 (residues 285-368).
Sequence:
MPSPTVTSPQVAVNDIGSSEDFLAAIDKTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPARELSIKHDVDPNEVVSVGDEVEALVLTKEDKEGRLILSKKRAQYERAWGTIEALKEKDEAVKGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRDLQPYIGKEIEAKIIELDKNRNNVVLSRRAWLEQTQSEVRSEFLNNLQKGTIRKGVVSSIVNFGAFVDLGGVDGLVHVSELSWKHIDHPSEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGLVHISELAERHVEVPDQVVAVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAETNEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAAEAAGRGADDQSSASSAPSEKTAGGSLASDAQLAALREKLAGSA
The following text describes a protein:
Function:
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSIASIDRVAAQGRWRNRPLAEKCLIGLGFLALAVTVPPFPGAVLVTVAILAFTFLGARVPLRFWAAVAVLPLGFLTTGAAVLLIQIGPDGIGLAPQGPAKAAALVMRASAATCCLLFLATTTPAADLLSGLRRWRVPAELIEIALLTYRFVFILAEEAAAMTTAQRARLGHATRRRWLRSTAQVIAALLPRALDRARRLETGLAARNWQGEMRVLSTRPAASPLVLGLILTLQAAILAAGVLL
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MQLASVFLFALAALSLYSSVFSLACYDDPSSASFPIIPVSLRKFRMSDEQLLFLRTDQSKSDGSSEEEDEGVDPTLRSLLAEPSEFQSDSCASRAHHRRRHRQSRHEPQPSRELVQKLRNYEIQHRRCAGRAMDEFLRPDADFARRGNSSEARNGSRDECRYVVWIAYSGMGNRLMTLVSTFLYALLTNRTLLVDGSTDMGELFCEPIPRSSWLLPTEITRDWTRTLNESSPRRFGHKFSVSDHASPTATAEFSYVHLTQTSDDKDQVFFCDRGQDQLDSKPWLFLRSNAYFVPGLLFVSQFRAELDLLFRDKEAVFHLLGRYLLHPSDAVWGWITRFRKAYLADHDHQVGIHVRTFGATPPPTVAEQIHRCVRNHHLLPRVTTTTTKKNFSGPDLARMSRNLEPATISVLVTSGQQYYYENLRDRFLSGPSEGGESVSVHRLSLEASQKTDASGHDSRAWAEIYLLSLSDVLVTSGWSTVGYCAQALAGIKPWILLDSVDGRPADPPCVQARSAEPCFQTPPQVHCCFEEVQNPAAALPYVQPCEDVPWGIQLITPAPPSRPI
The following text describes a protein:
Function:
Acts antagonistically to MID2 in signaling cell wall stress to the PKC1-MPK1 cell integrity pathway.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MSEIQNKAETAAQDVQQKLEETKESLQNKGQEVKEQAEASIDNLKNEATPEAEQVKKEEQNIADGVEQKKTEAANKVEETKKQASAAVSEKKETKKEGGFLKKLNRKIASIFN
The following text describes a protein:
Function:
Plays a role in inorganic sulfur assimilation during sulfur-limited conditions; catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway. Also catalyzes the conversion of O-acetylserine (OAS) into cysteine, the last step in the cysteine biosynthesis pathway. However, it seems that in S.cerevisiae cysteine biosynthesis occurs exclusively through the cystathionine pathway and not via direct incorporation of sulfur into OAS (By similarity). It therefore has no metabolic role in cysteine biosynthesis and may only have a regulatory role controlling OAS levels (By similarity).
Miscellaneous:
MISCELLANEOUS: Present with 2070 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MTEIEFGQPLPSNLDYAVSFGIPTWDSAIGYAEKVPEVIGKMATGYPRYFPQPPVQRLCAYFVKKFGRGSENCRPFPSVNLGLKCFEYVKSVSGPESKAHLEVETVTIKNRGAKTSKEPAELVLTIAAVLASEEEFETVKEYWKLRGECVSSRLALSVNQLLDCANHGSEQVLRELEAGVFAAKKGEEKAKNLIKGRIVENRFRPFGLEKKTPNWEGLNLNPNEDVYLVSSGMSAISTARNLLTFWEEKKNSGDSLNKTTSDQKKKPLLCDTVGIFGFPFKDTQVIMTKFGKCKFFGFGNSRDVVELQKFLETSKQRILAVFVETPSNPLLNMPDLKKLRSLADQYGFFIVIDDTIGGLNVDILPYADIVSTSLTKLFNGASNVMGGSVVLNPKSSLYPYAREYFRSANFEDLLWCEDAIVLERNSRDFEDRTLRANANTGILLNDLLLPEEGKICKKIYYPTVTSKETFENYESVRNERGGYGCLFSVAFFNEGDAKAFYDSLKVFKGPSNGTNFTLACPYVHLAHHSELEEVSKFGADPNIIRVSVGLEDIQWLLKVFSSALDVVKSRGSKHS
The following text describes a protein:
Function:
Member of the two-component regulatory system PhoP/PhoQ that plays a role in the regulation of resistance towards polymyxin B and cationic antimicrobial peptides in response to limiting concentrations of Mg(2+). Functions as a transcriptional activator by direct binding to a cis-acting sequence upstream of the target gene promoters including oprH and pmrH promoters.
Sequence:
MKLLVVEDEALLRHHLYTRLGEQGHVVDAVPDAEEALYRVSEYHHDLAVIDLGLPGMSGLDLIRELRSQGKSFPILILTARGNWQDKVEGLAAGADDYVVKPFQFEELEARLNALLRRSSGFVQSTIEAGPLVLDLNRKQALVEEQPVALTAYEYRILEYLMRHHQQVVAKERLMEQLYPDDEERDANVIEVLVGRLRRKLEACGGFKPIDTVRGQGYLFTERCR
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
Subcellular Localization:
Nucleus.
Sequence:
MLLLTVNLLIASSAAWAWGALAASPQDMAVNEETWFLLSNLLAPVTPQNFVDSYYRRDLLHVPAAASSWSQLAAADPWLKGLRNVDAFLLETYAQLRTIPQAVNYKTPTGADRPAPPAATWSEEAARFHDSGESLVLRREATTAPLSKLELALQAAFQTNRVTAHAYISSGGAQALPFHTDRCAYDSGCDINCAPCPECVFGCAGTCASVNCEPGMYFIPDDENVSSATCQATDKPPENLMSVWQLHFFYLFYLFYLFYLFYLFYLFYLFYLFYLFYFIDFIDLFILFILFILLNFLNFLNFLNIFNIFILLNFLNFLNFLNIFNIFNFLNFLNIFNFLNIFNIFNLFNLFNFLNLFNLFNFLNLPNLSCLHHFPCLLNLSCLPDQRHCRSNSSVGCTGKHISYKLFSLSGGRGRLGTKHEAQVQTRYQTRPKLVLAEVIEPKDAHHRRALMAEMRFFKELAWHPHRAERPAQLSNMPIMVFKLLRRCWQFDPQLRPTGAQIAREMEDTYSLYEMPNQPDTAWGERYAEVMGAGQLYETLEVELVSSDATASTSTNIYNNSSETEDSLYAEPADVFDSNTYDLASPARRATLSHQPSVAGVNLDVTEL
The following text describes a protein:
Function:
Endonuclease that is involved in the suppression of homologous recombination and thus may have a key role in the control of bacterial genetic diversity; Acts as a ribosome collision sensor, splitting the ribosome into its 2 subunits. Detects stalled/collided 70S ribosomes which it binds and splits by an ATP-hydrolysis driven conformational change. Acts upstream of the ribosome quality control system (RQC), a ribosome-associated complex that mediates the extraction of incompletely synthesized nascent chains from stalled ribosomes and their subsequent degradation. Probably generates substrates for RQC.
Sequence:
MEKKVEAILEFDKIKKQLTEFASSSLGEQAILELAPATDFQVVQKTQLETEEGAKIIRLRGSAPITGLTDVFAHLKRLEIGGDLNGLEIYQIGSNLRVSRQMKNFMNDLLEIGVELPILGALSDELLVLKEVEEDIAISVDESGKVLDTASEALSTIRRTLRRTEDRVREKLESYLRDRNASKMLSDAVITIRNDRYVIPVKQEYKGHYGGIVHDQSASGQTLFIEPQSVVDLNNERKALQAKEKQEIERILAEISASLAAWINEIHHNTFILGRFDFIFAKARFGKAMKAVTPHLSDAGVVHLIAARHPLLDAAKVVANDIYLGEDFTTIVITGPNTGGKTITLKTLGLLTLMAQSGLQIPAQEDSTIAVFEHVFADIGDEQSIEQSLSTFSSHMTNIVSILEKVNQKSLILYDELGAGTDPQEGAALAIAILDASHEKGASVVATTHYPELKAYGYNRVHATNASVEFNVETLSPTYKLLIGVPGRSNAFDISRRLGLSENIITEARSLVDTESADLNDMISSLEEKRNLAETEYEEARELARGADNLLKDLQKEITNYYQQKDKLIEQASEKAATIVEKAEAEAEEIIRELRTMQLNGAAGIKEHELIDAKTRLGNAKPKTINKTIPQAPKQKPHVFQEGDNVRVLSLGQKGTLLNKISDKEWNVQIGIIKMKIKTADLEYIQPEKPKKQRIITSVHSSGSPAKSELDLRGERYEDALQKVDKYLDEALLAGYPQVAIIHGKGTGALRTGVTEYLKNHRMVKSIRFGAAAEGGNGVTIVEFK
The following text describes a protein:
Function:
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MKNILRYGLTLMLICAIAAGVLAYTYENTQKVIELNKAKERNLLLKELLPEAIEFVPLSNKPKNIDPLVNINEIYIGKRDGKEVGKVWEVSTKGYSSDIVLLVAVNDKGVIEKVKVVSQQETPGLGTEVTKDNFLGQFIGKKEPNLEAKKNITPVSGATISSSAVVRAINEVLKHNRI
The following text describes a protein:
Function:
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
Domain:
Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
Sequence:
MYYTEESLETLKHSIDIVSVLGEYVHLKRSGADYKACCPFHDEKTPSFIVYPTRGHYHCYGCGEHGDAINFLMKQQGYSFSEAVLFLAKKFHVDLVVRTKETSGQDSKDSLRRINREAERFFQYCLLHLPEGEEALAYLYKRGFSPDTIDRFQIGYAPEQRLFIQAMEERNISVKQLEWAGYLAKDWFLFAQRIMFPIQDALGYTIGFSSRRFKEGGRGGKYINSPETILFKKSRVLYGLQFSRKRIAKERRVILVEGQADCLQMIDFGFNCTLAAQGTSFTETHVHELVKLGVSKAYLLFDGDAAGEKASLRVGDLCQAAGITAIVCRLPSGQDPDSFLMQRGPEELRELLDRGEDYLSFLVWHKIHSYEQFTPREKARVIEEVIQQVRCWGSPITIHEYLRQLASLVKVPEPAVLSYLSSITSAAEDKGKKVSAKEPSSESKQTSTEGKISKKISPRMILEADVIRCLLFAKPEDEFVPATVKQYLSPEEFHCAEYRAIFVMAMNHYNDRQTLPSMDEMMSLVVGTEAMTLLVARRMNTELMRDIVVQSIQKLLDKHWRDKKRKLCHQTGKGLDSLQEYVRLSGERVKVSLVS
The following text describes a protein:
Function:
Essential component of the TIM17:23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Links the inner and outer membranes (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MAINRSSDHESDENTRLYHPYQNYQVPIKSQYLYKLPTSPEFLFTEESLKQRRSWGENLTFYTGTGYLAGSVAGASAGIFSGIKSFENGDTTKLKINRILNSSGQAGRTWGNRVGIVGLIYAGIESGVVAVTDKDDVWTSVVAGLGTGAVFRAARGVRSAAVAGAFGGIAAGAVVAGKQVFKRYAHI
The following text describes a protein:
Function:
Metalloreductase responsible for reducing extracellular iron and copper prior to import. Catalyzes the reductive uptake of Fe(3+)-salts and Fe(3+) bound to catecholate or hydroxamate siderophores. Fe(3+) is reduced to Fe(2+), which then dissociates from the siderophore and can be imported by the high-affinity Fe(2+) transport complex in the plasma membrane. Also participates in Cu(2+) reduction and Cu(+) uptake.
Miscellaneous:
MISCELLANEOUS: Present with 892 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MVRTRVLFCLFISFFATVQSSATLISTSCISQAALYQFGCSSKSKSCYCKNINWLGSVTACAYENSKSNKTLDSALMKLASQCSSIKVYTLEDMKNIYLNASNYLRAPEKSDKKTVVSQPLMANETAYHYYYEENYGIHLNLMRSQWCAWGLVFFWVAVLTAATILNILKRVFGKNIMANSVKKSLIYPSVYKDYNERTFYLWKRLPFNFTTRGKGLVVLIFVILTILSLSFGHNIKLPHPYDRPRWRRSMAFVSRRADLMAIALFPVVYLFGIRNNPFIPITGLSFSTFNFYHKWSAYVCFMLAVVHSIVMTASGVKRGVFQSLVRKFYFRWGIVATILMSIIIFQSEKVFRNRGYEIFLLIHKAMNIMFIIAMYYHCHTLGWMGWIWSMAGILCFDRFCRIVRIIMNGGLKTATLSTTDDSNVIKISVKKPKFFKYQVGAFAYMYFLSPKSAWFYSFQSHPFTVLSERHRDPNNPDQLTMYVKANKGITRVLLSKVLSAPNHTVDCKIFLEGPYGVTVPHIAKLKRNLVGVAAGLGVAAIYPHFVECLRLPSTDQLQHKFYWIVNDLSHLKWFENELQWLKEKSCEVSVIYTGSSVEDTNSDESTKGFDDKEESEITVECLNKRPDLKELVRSEIKLSELENNNITFYSCGPATFNDDFRNAVVQGIDSSLKIDVELEEESFTW
The following text describes a protein:
Function:
Regulator of the Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway.
Subcellular Localization:
Nucleus. Cytoplasm, cytosol.
Domain:
The C2-domain mediates homodimerization.
Sequence:
MIRKELPLPEGWEEARDVDGKVYYIDHTSKTTSWIDPRDRFTKPLTFADCIGDELPLGWEESYDTQVGVYYIDHNSQTTQIEDPRVQWRREQERMLKDYLVLAQEALLAQKEIYQVKQQRLELAQKEYRTLNDVWKHKVGSQTSLVSGSSSSSKYDPDILKAEIATTKSRVNKLKREMVFLRQELQYKENGYQTLKEIDLKMSKNHCAYKLDEAQAILNEMKTIKKAITSGEREKQDLIQSLAELKNGFLVDKGSQSDLWASNTSLASSANSLSRQYLNVSSQTDISGNLSVVSNNHLAEKVRLQLRYEEAKRRIANIKIQLAKIDSDAWPGVLDSERDRLILISEKEELLKEMRFISPRKWSQSEVERLESEKKQLEEDLQAARDTQSKALTERLKMSSKRNQLVKELEETTRLIASLQAQLKCLSTSMQSLSSGSSPGSLASSRGSLVTSSQDSSTSASVSDLYYEQLDHLDSEYQNKVDFLIQEGAMGYRPSGCITTIHENEVVRSQKTDPANRVKALRSLSGTPKSMTSLSPRSSLSSPSPPCSPLVTDPLLTVDAFLSQIDFEDIDLPLSFTELNVNAGGDSYQHETDEEPSGQGLSCLGVSSLSVAGVSAAVSDESVTGDSGVYEATNQRTLMENAVFDGEDSEMMDTAKIKIGMKYDEKNKHFAVFVIQLDNLAALLLHQNEKLYIRVAVLPCSESTSCLFRTRTLEQSDTLLYNEMFLVSTSHSALRQKTLRVDVCTRQSNHHEECLGGSQISLADVCHSEEQEAHWYNLLSYRYLKRQSKTSKQKISCCEESGIENPDSVSALLKQTAAELEAVRKQIGESTDPPEYIWPEKKDNVPDEDGISENEGEEEFDGDVQCETEESDMQAATDSASVKVDKETNTEGLAMSLSSVRPKDKRAATPMQAPFIRGNTIIRSKTFSPGPQSQYICRLNRSDSESSTLSKKPPFVRNAMERRSVRVKRPSVKSTGSERLIRTSLDLELDLQASRTWHHQLTQEISVLRELKEQLEQAKRLGENELPQRVKDDETFKVMLRQVEKQVQKIEQKYEMQADKMMRAAAKDVHRLRGQSSKEPLEVQSFREKMAFFTRPRMNLPTLTADDV