lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans.
Subcellular Localization:
Lysosome membrane.
Sequence:
MDGRRLPCSRPLGLCVLVCLATAALLGHVLLHDFTMVPRELHGFSQVPKEIYRAPQQGASGPGPQPAPGRRGSPRAAPAQCDTPPDSRFDCAPDKAITQEQCEARGCCYVPARRQPPGSQMGQPWCFFPPSYPSYKLGNLTTTEMGYTATLTRAAPTFVPKDILTLRLDVLVETESRLHFTVYGPLCLTWLPTGGAPLLALWIKDPANRRYEVPLETPRVRSRATSTLYSVEFSEEPFGVVVRRKLNGRVLLNTTVAPLFFADQFLQLSTSLPSRYVTGLAEHLGPLMLNTNWTKITLWNRDIAPTPSVNLYGSHPFYLVLEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYVFLGPEPKSVVQQYLEVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDARRDFTFNKDGFGDFPAMVQELHQGGRRYMMIVDPAISSSGPPGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPEALDWWQDMVAEFHAQVPFDGMWIDMNEPSNFVKGSVDGCPDSDLENPPYVPGVVGGTLRAATVCASSQQFLSTHYDLHNLYGLTEAIASHRALVKARGVRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLSYSVPEILLFNLLGVPLVGADICGFLGNTSEELCVRWTQLGAFYPFMRNHNGLDSLPQEPYRFSETAQQAMRKAFALRYMLLPHLYTLFHGAHTRGQTVARPLFLEFPEDPRTWTVDRQLLWGEALLITPVLEAGRVEVTGYFPLGTWYDLQTVPVGALGGLPSPAPAPLMPAIHSEGQWVTLPAPLDTINLHLRAGHIIPLQGPGLTTTESRKQPMALVVALTSSREAQGELFWDDGESLGVLEREAYTHIIFLARNNTIINELLHVTSEGASLQLERVTVLGVAVAPQQVLSNGVPVSNFTYNPDTKTLDIPVSLTMGEQFLISWS
The following text describes a protein:
Function:
Calcium-regulated non-lysosomal thiol-protease.
Sequence:
MFSCVKPYEDQNYSALRRDCRRRKVLFEDPLFPAADDSLYYKGTPGPAVRWKRPKDICEDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKPNAYAGIFHFHFWRFGEWVDVVIDDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDVRKVRLGHGLLAFFKSEKLDMIRLRNPWGEREWNGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCQYFTDIIKCRVINTSHLSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFDVKKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCGYPQLVTQVHVLGAAGLKDSPTGANSYVIIKCEGDKVRSAVQKGTSTPEYNVKAIFYRKKLSQPITVQVWNHRVLKDEFLGQVHLKADPDNLQALHTLHLRDRNSRQPSNLPGTVAVHILSSTSLMAV
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSDKNKKVSAFAAYRGSATSKNDVQKGTKNSDKNGAAKNNNNRNLASKNGGKQKGPPKKNGSYSDGDNGSSSSSGEDEEDDSTDSSDEYESSESGEEYTLNSHSSQSSPETPANTRESLKRRNDEAEGSNPIGAKRTSSTPVGQSTSAARSTQQPKAPSCPLQRRSCPLPSKKNTVPVKVEVASPDRALLSPQSIKKEPGASMLCRIKIGLVKSVQPGGDAGAEAGAGQAVNRLEPCHKVHKENSIEVGKRTLAQLIAPMTMATFLRDHWEKSPFRVKTTTSGGFSNLISFKMIDQMLIQNHVEYTTNIDVTSYEDGVRKTLNPDGRALPPSVWAHYQRGCSIRILNPSSYLVQLRQLCVKLQEFFHCLVGANVYLTPPESQGFAPHYDDIEAFVLQVEGKKRWRIYAPTKELPRESSGNLSQTELGDPIMDIVLKPGDLLYFPRGWIHQAITEKDSHSLHITLSAYQQQSYANLMEKLMPLVVKESVEQTLKLRKGLPLDIFQNLGVANAEWKGAHRQKLIQHIQNLAQRLVPTEGQIDRALDQLAIKFQHEALPPTIAPQELKRTVFGAQATADRNGHCSLDYELAEGTAVRLLRANIVRLTVDEGVLRCYYYTDNGLEYCKYEPNFFELEPFHGTVIETLIHAYPEYTKIKDLPPMGNDEDRLEFVEALWERGILMVEKPFKKL
The following text describes a protein:
Function:
Bacteriocin active against Gram-positive bacteria. Inhibits B.cereus spore outgrowth, after the germination stage, approximately 1000-fold better than it inhibits exponential growth of the same cells. Inhibits B.subtilis strain ATCC 6633.
Subcellular Localization:
Secreted. Note=Extracellular region.
Sequence:
MEKLFKEVKLEELENQKGSGLGKAQCAALWLQCASGGTIGCGGGAVACQNYRQFCR
The following text describes a protein:
Function:
May function as sodium-coupled metabolite transporter across the chloroplast envelope.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Plastid, chloroplast envelope.
Sequence:
MSDRNLSYSFVNEESGVTICHEMVYTTSNGYWRGEDPLTTSLGSFTMQIITILVITQFLYYIFKPLKQSRFVVEIIAGIIMGRSVLKRFKRWEDSVLPIWMDNLIRTIGYLGMSLLIFLSSVKMNPRIIFTSGKRTIVIAFIAMVLTILVATGTVVVASRKVPDRILHGTFVVFIPATVALTGFPNVALVLAEYGLLNSELGQLSLNTSLIHDYFGWFFMALFAGVGQGQIQPLTTLWSMLLLVALIMIVIFIFRPWMKWIVRRVPMGGHIGEEYLTAILLSALVLGLLSDAIGCTVAIGPMILGLATPNGPPLGSALVDRAELIVMEVFLPMLFITSGMTTDLSVLVPPKVNQYAPLYVVFLVGFATKFIGIFVPSLFFDMKLKNSVVFGLMMNIKGFIEVMVFQILWSGGLLEDEGYSVAILCTTFLMILLTPVMVYLYDPLENVVSVFDRRTISQVRSSDMLRVLICVHNEDPVPYMINLLDMFNVTDPKVTIDVYMINLVELQGRAIPMLIRHNSEKDAKDPVTKAFKNYSNRTNGLVRVKMYTTISPYRSMHIDVRKIAEENLVSVVIFSFCKKGKIGKADHAMRTMTPTVLDNSSCSVGILIHDVPIYSRPMHHVGVIFWGGPDDRDALAFATYIANREGVTVTVHRYMHTQTQTQSQSQTQTEHNVAVDELLETRMDDEAVTEFKTRTIRPDNADSKKVTVIESMLDDPMQIVEQITSFGQNYDLLIVGHTQRALSNVMTEWSDRPELGVFGDMLASTTLKICPVLVLHCNQRETT
The following text describes a protein:
Function:
Unknown. In males lacking the Y chromosome, its strong overexpression leads to the appearance of proteinaceous star-shaped crystals in the primary spermatocytes causing meiotic drive, possibly by interfering with normal casein kinase 2 activity.
Miscellaneous:
MISCELLANEOUS: There are multiple copies of the stellate gene in fruit fly, encoding proteins that are extremely similar, which makes their individual characterization difficult. Thus, most experiments probably do not discriminate between the different members.
Sequence:
MSSSQNNNSSWIDWFLGIKGNQFLCRVPTDYVQDTFNQMGLEYFSEILDVILKPVIDSSSGLLYGDEKKWYGMIHARYIRSERGLIAMHRKYMRGDFGSCPNISCDRQNTLPVGVSAVWGKSTVKIHCPRCKSNFHPKSDTQLDGAMFGPSFPDIFFSMLPNLTSPLDDPRT
The following text describes a protein:
Function:
Essential for the control of the cell cycle at the G1/S (start) transition.
Subcellular Localization:
Nucleus.
Sequence:
MPREKKERDAKEPDTMKEESGTDVSVRSRKRKANVAVFLQDPDEDVAKIDRTVRSQCGNQPWDNNAACENPCSFIPTPDKEEDELVYPNSVYKPQSCTPSRASPLPILNWANREEVWKIMLNKEKTYLRDKHLMQRHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQQNVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELIIMKALKWHLSPLTIVSWLNVYMQVAYLNDFYEVLLPQYPQQIFIQIAELLDLCVLDVGCLEFPYGVLAASALYHFSSSELMQKVSGYQWCDIEKCVKWMVPFAMVIRETGSSKLKHFRGVPAEDAHNIQTHINSLDLLDKAQAKKAILSEENRISPLPTGVLTPPPSSKKQSSGQGTA
The following text describes a protein:
Function:
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(o) and JIP (By similarity). Inhibits G(o)-alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1 (By similarity). By acting as a kinesin I membrane receptor, plays a role in axonal anterograde transport of cargo towards synapses in axons (By similarity). May be involved in copper homeostasis/oxidative stress through copper ion reduction (By similarity). In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation (By similarity). Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1 (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, growth cone. Membrane, clathrin-coated pit. Early endosome. Cytoplasmic vesicle. Note=Cell surface protein that rapidly becomes internalized via clathrin-coated pits. Only a minor proportion is present at the cell membrane; most of the protein is present in intracellular vesicles. During maturation, the immature APP (N-glycosylated in the endoplasmic reticulum) moves to the Golgi complex where complete maturation occurs (O-glycosylated and sulfated). After alpha-secretase cleavage, soluble APP is released into the extracellular space and the C-terminal is internalized to endosomes and lysosomes. Some APP accumulates in secretory transport vesicles leaving the late Golgi compartment and returns to the cell surface.
Domain:
The OX-2 motif shows some similarity to a region in the N-terminus of CD200/MOX2.
Sequence:
EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVMSQSLRKTTREPLTRDPVKL
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. QCR10 has a role in CIII assembly and RIP1 stability.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MVTRFLGPRYRELVKNWVPTAYTWGAVGAVGLVWATDWRLILDWVPYINGKFKKDN
The following text describes a protein:
Function:
Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
Subcellular Localization:
Cytoplasmic vesicle lumen.
Sequence:
MYKDKPYFAPRRTGPRARRRKIIYSGLCLFVLLALWYYSGSGKPEWKTPDAEKGAELWKWVQSFEESEPPYDGSAATEKIDWEARREKVRDVFIVSWDGYAANAWGYDEYHPIAKNGRHMIEGGMGWIIVDALDTLMIMNLTSRVQHARSWIHNSLQYNQDHDVNTFETTIRMLGGLLSAHYLSTNYPELAPLTDDDTGAPGEDLYIEKATDLADRLLGAFESGTGIPYASINLNKSEGLPSYADNGASSTAEATTLQLEFKYLAKLTGEAEYWQAVEKVMEVVDDQKMEDGLLPIYVYPETGEFKGDNIRLGSRGDSYYEYLIKQYLQTQETEPIYKDMWDESLVGVRKHLITYTQNAKLTVLGERPAGLHGVLSPKMDHLVCFYPGTIALAATGGRPLSEARQSPDWGQRQEEEILLARELTKTCWATYLITKTGLAPEITYFNVDDPRVMETDIDYSTKWRDDLNIHKQDRHNLQRPETVESLFYMYRITGDDIYRHWGWEMFKSFVKHTAVKITGFTSLSNADDNPPVKRDNMESFWMAETLKYFYLLFSDRDFISLEDHVFNTEAHPLPRFKPTGELKTGWMRKSRTIPTSSEVEESV
The following text describes a protein:
Function:
Binds to 23S rRNA.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MIQPQTYLNVADNSGARKLMCIQILGASNRKYAHIGDIIIAVVKEAIPNMPLKKSEVVRAVVVRTCKELKRKNGTIIQFDDNAAVIINQEGNPKGTRVFGPVARELRESNFTKIVSLAPEVL
The following text describes a protein:
Function:
Functions as a component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Miscellaneous:
MISCELLANEOUS: Present with 3060 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytoskeleton, actin patch.
Sequence:
MEADWRRIDIDAFDPESGRLTAADLVPPYETTVTLQELQPRMNQLRSLATSGDSLGAVQLLTTDPPYSADAPTKEQYFKSVLEALTQVRQADIGNVIKNLSDSQRDVLVKYLYKGMSVPQGQKQGGVLLAWLERITQVSGVTPIVHYISDRRTV
The following text describes a protein:
Function:
Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Is an electroneutral proton-solute symporter: the number of protons transported is equal to the valence of the transported anions. Translocates the free citrate and malate anions. Citramalate binds to the transporter, but it is not translocated. Is strictly stereoselective, recognizing only the (S)-enantiomers of malate and citramalate.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGELQTHMQLQTDTIHEGVRKENWFAKAMNIKVGIIPLPVYALLFILITVFVMHHDVKSDILTSIAVMAFFGFTFAQIGKSIPIVRSIGGPAILATFIPSAVVYYHLLPNDIVKSTTEFTENSNFLYLFIAGIVVGSILGMKRETLVKAFMKIFIPLIVGSVTAAIVGLAVGTLLGLGFQHTLLYIVIPIMAGGVGEGAIPLSIGYSDIMPISQGEAFALVLPSIMLGSLCAIILAGLLNRIGKKKPEWTGNGKVDRSEEESPALEESQSGQQMFNLSLFASGGILAVSLYLVGMLAHDFFGFPAPVAMLLLAVLIKLFRLVPASIENGAFGVSRFFSTAVTYPLLFAIGVSMTPWDKLVAAFNLSNIITILSVVVTMMAVGFFTGKWLNMYPIETAIINACHSGQGGTGDVAILSAAERLELMPFAQVSTRIGGAITVSLTLLLLHQFY
The following text describes a protein:
Function:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MSRLLQTPFLPSVSLPTKTRSSVTGFRVKPRIIPIQAKIREIFMPALSSTMTEGKIVSWVKSEGDKLNKGESVVVVESDKADMDVETFYDGYLAAIMVEEGGVAPVGSAIALLAETEDEIADAKAKASGGGGGGDSKAPPASPPTAAVEAPVSVEKKVAAAPVSIKAVAASAVHPASEGGKRIVASPYAKKLAKELKVELAGLVGSGPMGRIVAKDVEAVAAGGGVQAAVAVKEVVAAPGVELGSVVPFTTMQGAVSRNMVESLGVPTFRVGYTISTDALDALYKKIKSKGVTMTALLAKATALALAKHPVVNSSCRDGNSFVYNSSINVAVAVAIDGGLITPVLQNADKVDIYSLSRKWKELVDKARAKQLQPQEYNTGTFTLSNLGMFGVDRFDAILPPGTGAIMAVGASQPSVVATKDGRIGMKNQMQVNVTADHRVIYGADLAQFLQTLASIIEDPKDLTF
The following text describes a protein:
Function:
Acetate transporter protein; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. May be involved in the uptake of acetate, a substrate for the synthesis of 6-methylsalicylic acid by the polyketide synthase patK (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MKLSAEGTVMASSEEAAQLSCDTSSSHARNSKEQDFQPTQQIGSPTALGMGAFAIAFTTLSMSLMEWRSAAITNAYIGNCFFTAGMGLVLVAQWELVRGNSFGHTVFGGFGLFNLAFGAINAPAFGVADAFKDDPAALNNAIGYFLLVWGIFVLFFTVAAMPMNLVYTGMLGTSQITYTLLAASYFSFADDHASAGLALKKAAGAFGFVSGLFAWYTVGHLMCQDALLFSFPLGDTSPLYARLQRKKRH
The following text describes a protein:
Function:
Probable transcription factor that may be involved in shoot formation during embryogenesis.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice site.
Subcellular Localization:
Nucleus.
Sequence:
MESFASLAGGGSSSTTARLPELISPENPDHISPPPLLYQLLAGPESSARQHGHDGHHHGGGGGEAAAAAVQGQVSPAGAEAAVKAEIMSHPQYSALLAAYLGCKKVGAPPDVLTKLTAVPAAQQLDEADGHPRRRHEPQRDDDPDQLDQFMDAYCSMLTRYREELERPILEAAEFFSRVETQLDSLAESNCEGTGSSEEEQDPSDKQLKHQLLRKYGGSLGDLRQVFSKRTKKGKLPKEARQKLLHWWELHYKWPYPSEMEKMTLAQTTGLDQKQINNWFINQRKRHWKPTPVAGTAFPTMEAAGGGFRHSGHGGGLAAAAALPLYMGRPFVVDGMYRLGS
The following text describes a protein:
Function:
In the developing eye, has a role in axonal targeting of the R7 photoreceptor where it functions together with tutl. Probably mediates homotypic cell adhesion; the effect is inhibited by Lar.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Cell projection, axon.
Sequence:
MPAKRSRTFRQSGSALLALLAIILLMNISCTSAARDHRRQTNLEAKVGSHVVFNCYIDFPFDAPIPYLVHWTKDNKKIFTWYEQETSTSELFNGRLHLVENHPEFGRASVNLTAIRESDQGWYHCQVSFPNRSPSVRNNGTAYHLAVQGGSLIRIPPVNQTIREGQTAFFHCVMKHPENSQASWYKDGVLLQEVQDLVRRFYMGPDGSLSIDPTMMSDLGEYECKVRNSDGELQTAKAFLNIQYKAKVIYAPPEVFLPYGQPAVLDCHFRANPPLKNLRWEKDGLLFDSYNVPGVFYKMNGSLFFAKVDENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPKAIYIQKLGEAAELPCEAIDRDGNNRPSIIWGRKDGQPLPADRFSLSGGNLTITGLVEGDRGIYECSATNEAATITAEAELMIENIAPRAPYNLTANSTETCITIRWQPGYLRPNLEYTVWYRLMEAPEWRTLRVLDKKVMEATVQHLQPGKEYEFMVLSQDKYGDGMFSKQFRFQTLPSPIRADDFDAQQLQHDLGQVTAPAGGLGAPWNLTAISNQQGWLLHWEHPVQGLEGLRLYAVRWWKEPEHFLIGHAETFDNYYQLRHLKEDTLFKVQVLAVGTETQQSVPSHELLIDVPSQRKVRALIIGSSVGVIFLLCALCAFLYVKRSCLRHLFAKDSSASEDEDTAESGDCDSDEQDQRDRDSIKIRQST
The following text describes a protein:
Function:
Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MDYIISAPGKVILFGEHAAVFGKPAIAAAIDLRTYLLVETTTSDTPTVTLEFPDIHLNFKVQVDKLASLTAQTKADHLNWSTPKTLDKHIFDSLSSLALLEEPGLTKVQQAAVVSFLYLYIHLCPPSVCEDSSNWVVRSTLPIGAGLGSSASICVCLAAGLLVLNGQLSIDQARDFKSLTEKQLSLVDDWSFVGEMCIHGNPSGIDNAVATQGGALLFQRPNNRVPLVDIPEMKLLLTNTKHPRSTADLVGGVGVLTKEFGSIMDPIMTSVGEISNQAMEIISRGKKMVDQSNLEIEQGILPQPTSEDACNVMEDGATLQKLRDIGSEMQHLVRINHGLLIAMGVSHPKLEIIRTASIVHNLGETKLTGAGGGGCAITLVTSKDKTATQLEENVIAFTEEMATHGFEVHETTIGARGVGMCIDHPSLKTVEAFKKVERADLKNIGPWTH
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein.
Sequence:
MVSPAVARFAVGILGNIISFSLYLSPMPTFIRICKKGSVEQYSATPYLLTFLNCMLWTIYGMPFIQPNNILLSTISASGCVIESVYLMLFIINTQNKKKKITLILLVLAEVLAVGIALALVLTFTHTTKRRTQIFGLLGDVSGVLMYASPLAVMKQVVKTKSVEYMPLAVSVTCFGSAVIWTLYAIRPFDPYVVAPNGIGCFLGLAQLMLYAAYYKSSKQQIADKQNAEIEKIEMGLKEVIVVTKEPSKVNDYPTLKTMENDFAPNL
The following text describes a protein:
Function:
Transcriptional activator.
Subcellular Localization:
Nucleus.
Sequence:
MDLKFSNFFKEAEHPALVKKFDKSTTDESSSKEDYSTMSDLWKMFSKAKSELSNGRRVENLTWRLMSINLQKNLTPNGDSNTLTPDTFSDPTAPSSAQSVPPTSSAETTADNSDTEMKLNPIPAYSVPADTTGSSLMEFNYIQRRVRKTSFDESTAKSKKRSIADSHFPDPNAMQRPHDLESQPFSYPKIHASNSFNFVKRDIDSSNFSNLDASALPISPPSDFFSVHSHNLPNAPPSIPANSNNSASPNQRIKASPKHADTDVLGLDFDMTPSEPSSFPENGGFPSFVDANTHEQTLFPSSATNSFSFEHGSAGFPIPGSVPSTSYHANTASEDGFSSSYNSQGLFGISSPLSSGVTPNQSFFPDVSGNNIFDVSRNNHEVSSPLIQSPGSYVSMPSINMVSSLPISAPVPNSNSQFPRRPNTFRTNSSKSVGQGSSGVDSNQENAESFNPSISSHNSAEWASGETTGHSSNSPLPGSDMFSPQFMRVGTAMGVAPVRSNSSNNFGQNFFHQTSPQFSAVPHRKVSAQDTNLMGSSPGMYNHMPYLNRATSANSITSPGVLPEGMAASLKKRTTNTAATPQAALPTTLDTKKDRSVSFNINKNAEKPTVSNAAEDKKGDANTRRANATNPTPTCTNCQTRTTPLWRRSPDGQPLCNACGLFMKINGVVRPLSLKTDVIKKRNRGVGTSATPKQSGGRKGSTRKSSSKSSSAKSTAADMKPKADSKSISPGFVGGNQSLSSERIPLDPSMRSPLQQQSSENESKSQSMLSANNLNAGVNDFGLGFSEGLGSAHLDSNDSSMVQGKNDFAPVVDSPLFDAFDTDLGMSSVAESHTMNMDPSDLSRVSKSWDWYSVM
The following text describes a protein:
Function:
Oxidizes aldehydes to the corresponding carboxylic acids with a preference for aromatic aldehydes. It might play a role in the detoxification of aldehydes to avoid cell damage.
Subcellular Localization:
Periplasm.
Sequence:
MSNQGEYPEDNRVGKHEPHDLSLTRRDLIKVSAATAATAVVYPHSTLAASVPAATPAPEIMPLTLKVNGKTEQLEVDTRTTLLDTLRENLHLIGTKKGCDHGQCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFIKHDGFQCGYCTSGQICSSVAVLKEIQDGIPSHVTVDLVSAPETTADEIRERMSGNICRCGAYANILAAIEDAAGEIKS
The following text describes a protein:
Function:
May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters (By similarity). May be involved in the regulation of B-cell, but not T-cell, development.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Note=Partially recruited to lipid rafts upon BCR stimulation.
Domain:
The ITAM domain displays no close similarity to any existing ITAMs, except for four conserved positions. The phosphorylated ITAM domain binds ZAP70 and SYK.
Sequence:
MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL
The following text describes a protein:
Function:
Transcriptional inhibitor with a significantly increased number of target genes in response to oleate.
Miscellaneous:
MISCELLANEOUS: Present with 149 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus. Mitochondrion.
Sequence:
MGYDSQVRTKKRHRITVVCTNCKKRKSKCDRTKPCGTCVRLGDVDSCVYLTDSSGQPESSPSLNDADPLRKQSTPAERISPGFIKKRRSSQTRQDEDHWQRVRELENQSSLYYLPIHEETPFFIDLIPNGFYLETKRSADNLFGLFTDRAIENRDPYLQAMVTFRSIAIKKMMDKLGSNGNNVKNGSLPKSFEALSTFDADDERHISDDVVGKGNNFRMHQTIHKSLFNKFAQYRENNAKKFSSETILAKDYLPPLKILESEVLALFEEKIYNMIPIFDMKVLRHEITIFYQNIVEKGNPISIKHYDHMVFCIILLIIKICRLSVQFSKLTPYIYPVLQEIDTSKFLALVKHYLFETKVLRKCNLLQLQCLILLRFLHWCAPEDGDGPETQYCQILMGTIISSCKEMGINWYCFSHPEKYSFKINRHTRPSYDIMKPSDYISVFRKIWSYVLFWDRKMCFISGEECQIGKTLQCHFKEEADTPTWYIRMLTLDNLMKKINDTLNDDPGKVDLNLLHRLINDLKRNFHILKSLSKNEKETMRHFDFEMEWIIDLFSLSLLHGEMIFYEYDCNITKFYKSFQDLWDMVIHISEKCYNYFFNSDALEVDSLTKFYTNRIVEIVANKVLVIVPAFILRGDRFKTIQYADKKKMIEFLYGVSSVYFNEFGFEYYRCFRKMFTAKIAYKILNRSCEKDAWRIILKFLLNELKLEDNGDSYIDYNDMRLNDICPIILEFQETVQKYDGYRPDILSIWNNEFYPIGKYNDDMTGFKFQMRIKEMQEFLDMEKYSDRFNIFSSFYDHASSQLAKHTEVDTNISITNEQVAEIPQKELLQQPLAPALPVNDLIVSEFDVIEDIFDPVDFVSFF
The following text describes a protein:
Function:
Repressor for the malX and malY genes. Also regulates its own expression. Binds maltose as an inducer.
Sequence:
MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTATGERVNAAIEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYAELTAGLTEALEAQGRMVFLLHGGKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRMAEEKAIPVIFASRASYLDDVDTVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSDWVLECTSSQKQAAEAITALLRHNPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDRYFEQQVSLAAFTDATPTTLDDIPVTWASTPARELGITLADRMMQKITHEETHSRNLIIPARLIAAK
The following text describes a protein:
Function:
Responsible for the reduction of the keto group on the C-3 of sterols.
Sequence:
MLICHQCLSSRLTYISNLGLNIAYRLIEQFTDDSKLVIVVTSRTLPRVREVVDLIKTYAEKCGKSGAVDFDYLLVDFTDMVSVLGAAYELEKRYDAIHYFYANAAQGVYSGIDWLGATKAVLRDPLDAVTNPTYKIQRVGVKSRDGLGLVFQANVFGPYYLIRRIIPLLAKGKAKVVWLSSLMSDVKYLSLEDVELLRTDSSYEGSKRLVDLLHLATYKELKSLGIHQYVTHPGIFTSHSFYQYLNFFTYYGMLFLFYLARWLGSPWHNIQGYKGANAPIYVATLANPTFEHQALKYGSATYRDGMEYIAKHEIDPTGMHDAYKYIRDLAEEWDIKLKDQITIGRSLS
The following text describes a protein:
Function:
Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MEKPVVISQRTGKPKRRKAHRACIHCQRTHLTCDNNRPCERCVARGFADTCVDGVRKKLKYLDDKEDNKPSKGLSPAPGVNVQPKLSPATRSARSSSAGFPDTKGNMQQQHMGNMPVPNTPQNGHPNLGTPGMAHTNLQGPQRQGAQQPQGGQSSTPSQLPADYLIHQQLLATEINQLGDLGRTGEGDFSSDWFSDLQLSGHSFQSVATNMEYSILSNMVYSSGQPNSAVSNSLLLGNNSQSPNTHSPHNQDQPTPQAATPSAKIKQLIESNGLSAKDLNQYPLAGEFVNDTFLTVPEIVAFNETRRNVKDSELTTDEKLRPLSFAVAAGQPQNTNGNGNGSEAPDSPSKSIFSSGALEAVYSNLPDYTDPIQVYTNITKPFSYTPGYHGLISYLKGRFNKQQLVQMTKYMAEYRPSFIACTNSLKEEDLVFMEQCFQRALLEYQKFISFSGTPTLVWRRTGQLAAVGKEFCQLSGWSEQRLIGQQTFIVELLDDNSVLEYFELFSRIAFGDSRGATMADCTLLTPTGAKIKTSSIWTLKRDVFGNPMMIVGNFLPILS
The following text describes a protein:
Function:
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.
Subcellular Localization:
Nucleus.
Sequence:
MDVYGLSSPDLLRIDDLLDFSNDEIFSSSSTVASSAASSSENPFSFHASPPPPPPLLTDFTHDLCVPSDDAAHLEWLSRFVDDSFSDYPANPLTVNVRPDASFTGKPRSRRSRAPSSPSLAGTWAPMPESELCYSVAKRSPSKKLEVESVTAEGGGGRRCTHCASEKTPQWRTGPLGPKTLCNACGVRFKSGRLVPEYRPASSPTFVLTQHSNSHRKVMELRRQKEQIESRFQPQ
The following text describes a protein:
Function:
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
Sequence:
MEMFVLKSSDDESFEVDEAVVLQSQLLSNLFEDCSGARECKIEEVTGQVLSKVVEYCKSHVVDGGDSSSSSSAAGDALKKWDDKFITRMDLSMVLDLIMTANYLNIKGLFDLTCQRVADEIAACKDHKEIRTKFGIVSDYTAEEEAEGRDGDTCDDTIASEGVGYSCL