lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Sodium-phosphate symporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAVMSEYLWFVIVGAFVAFAFGWGNGANDLANGFATSVGSKTLTMGQAVMIAIVFDFLGAILLGRVVTSTIASGVADINAFIGNPEVYAYGMICACTAGSFWLAVASRIGVNVSGTHFIVGGIVAFSLIWDGKDAVIWAERDNSIDAFPFKGVISIVTSWIMSPILAAAGGALLFWVLRSLVLRRKNAYKVAFWTLPPTILITVFINFYFIFTKGAKKQMDKDGVHWSYSKTAWISACIALGAAVLSALTVVPFLNSKINSTFDEQGNRLHPDDLEAPVKKETFAEASTGGKIWKVVSHGWTQDIHDVIITNKTVAEIHSNAEVFEPRVEYAFMYLQVFSAICVIFSHGAGEVGYAAGPMSIILQVYEDGVLTKNIQPKIWVVVFGGLALISGLATYGYHTMRTMGVKLTKVTPTRGFCAELATAMVVMVASQ
The following text describes a protein:
Function:
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKRANEIMAGGREKKKTKDDGKMESLYRPLTSEELGELKETEQLFHSSLIRLQIKELIEEIQIKKKNEALEDTLHALNEVLLAIPDGKKEYELSDMSWLPRKVVFPLPPTPSPVKGKFKFLKPAAVNIVGSYQLKTAIKPSFNVDVSINMPKECFQDKDYLNMRYLHKRAAYLCVVAHHVIKSKLFQTVRFVNTDGDILRPVLSLKPKGKAGKNCTVRIHPVISNEVFKLQRLAPNKSNVRLNWLFPEASSSSVLPTPHYNSLILRDMVLGGHLRCLFQCMNDCPSAREAIMLLSVWLRQRELDEGQGGFSRFLVSMVIAHLHTTRKINSYMSSYQIVRIFLQFISSSDWTTCTAMKKDQNSDENNLPSLSCHHAAFDVVFVDPSGYLNLCANVSKSTYYRVRHEAKLSFHLLDDRFVDGFYAMFMKPVPFMQKFDQCFSLANIECLKNVTERVELQPSILSHAGDWVPVAVSWLVELLHKGLGKRAEMIYVKPSACKEWSVRENPPTLQQDSVTIGLILDTDHSDSILDYGPPGDNTLEAAIFREFWGSKSELRRFKDGSILEAVVWPSSSAGERRTVCERIIKYLLNRHGKVEPEMVRFVSSQLDCLLQRNNGTSTTPSESQQAPTSSSIQGTGEESMSLVIKAYDSLCKDIRGLELPLAVHSLQGISPIFRGAEVHPPNPCISSPQSKNSHQDKENNRNMASSVALPTDSKVPPWCPVMTVLLQFETSGKWPDDLAAIKHVKAAFHIRLAQQLKEKLGLVAATSPTCVDVVKDGFVFRVKIVHYREMVLLQEPGDEIDSHLRQSQAVAMEKEIVWLPALTSTLHGIQQQFVAYSGCVRLAMRWVCSQLLFSHIPSECVELLVASLFLSPAPLTPPHSALCGFMRFLHVLATCDWKTTPIIVNFNNDLTAENYQEISSKFSSNRAHLPPLFISTPKDRFDSKWTRNAPSSMILQRVRVLAQESYNVMKETLESTEPPDLKPIFRPPIDGYDVIITLHSRMLPRRDEAVDVDKPLKKKAHSARNKADELPVVDFDPAECYLRELREAFSDIALFFHDPHGGDMIAVLWRPNALSPALFKVLHAEYKAPVKESLTSSKKRTAHAPTVEPNIPAILEDFKIIGEGLVKSVQSLKKNTDQYMNTP
The following text describes a protein:
Function:
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
Sequence:
MTQDASPILTSLLDTDAYKLHMQQAVFHHYRHITVAAEFRCRSDELLGVYADEIRHQVTLMGQLALTSDEFIYLSSLPFFQDDYLHWLRDFRFKPEQVSVAVHDGKLDIRIAGLWCEVIMWEVPLLAVISEIVHRRRSTQVTTDQAVQQLRTKLEQFNALSADIDITHFKLMDFGTRRRFSREIQHTVVSTLKDEFPYLVGTSNYDLARTLALAPVGTQAHEWFQAHQQISPTLANSQRVALQVWLDEYPNQLGIALTDCITMDAFLRDFDLAFANRYQGLRHDSGDPIEWGEKAIAHYEKLGIDPMKKVLVFSDNLDLEKALFLYRHFYQRIKLVFGIGTRLTCDIPDVKPLNIVIKLVECNDKPVAKLSDSPGKTICQDPAFVDQLRKAFALPLVKKAS
The following text describes a protein:
Function:
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKTPLSIAHPWHGPVLTRDDYESLCCYIEITPADSVKFELDKETGILKVDRPQKFSNFCPCLYGLLPKTYCGDLSGEYSGQQSNRENIKGDGDPLDICVLTEKNITQGNILLQARPIGGIRILDSEEADDKIIAVLEDDLVYGNIEDISECPGTVLDMIQHYFLTYKATPESLIQAKPAKIEIVGLYGKKEAQKVIRLAHEDYCNLFM
The following text describes a protein:
Function:
Transcription factor involved in senescence, biotic and abiotic stress responses by modulating various phytohormones signaling pathways. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Binds to the 5'-[CT]GACTTTT-3' motif in promoters of target genes to induce their expression. Binding to the W-box element of PR-1 promoter is mediated by not-sumoylated NPR1 in the absence of salicylic acid. Plays an important but not indispensable role in jasmonate and salicylic acid signaling. Positively regulates the salicylic acid (SA)-mediated signal pathway, but negatively the jasmonic acid (JA)-mediated signal pathway, thus determining the balance between these mutually antagonistic pathways. Together with WRKY46, WRKY53 and WRKY54, prevents defense response to the necrotrophic pathogens P.carotovorum and B.cinerea, but promotes defense responses (including SA-induced pathogenesis-related (PR) genes expression) against biotrophic/hemibiotrophic SA-monitored pathogens (e.g. P.syringae, E.carotovora subsp. carotovora SCC3193 and E.cichoracearum), probably by regulating negatively the JA/ET and positively the SA signaling pathways. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of JA-responsive genes (e.g. PDF1.2). Promotes susceptibility to JA-monitored pathogens (e.g. A.brassicicola), probably by facilitating SA-controlled suppression of JA-mediated defense. Represses the biosynthesis of the phytoalexin camalexin and indol-3-ylmethyl glucosinolate (IGS). Represses both SA and JA/ethylene (ET) mediated defense marker genes expression. Negative regulator of SA biosynthesis. Negative regulator of EDS1-dependent defense against E.amylovora. Required for RPP4-mediated disease resistance and basal defense against H.parasitica, probably via late up-regulation (LURP) of resistance genes (e.g. CML10/CaBP22 and LURP1). Probably involved in defense responses toward insects (e.g. P.xylostella and B.brassicae). Together with WRKY54, negative regulator of developmental senescence, probably via the regulation of several senescence-associated markers genes. Together with WRKY46 and WRKY54, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression. In collaboration with WRKY54, prevents stomatal closure and, consequently, osmotic stress tolerance. Regulates rhizobacterium B.cereus AR156-induced systemic resistance (ISR) to P.syringae pv. tomato DC3000.
Subcellular Localization:
Nucleus.
Sequence:
MDTNKAKKLKVMNQLVEGHDLTTQLQQLLSQPGSGLEDLVAKILVCFNNTISVLDTFEPISSSSSLAAVEGSQNASCDNDGKFEDSGDSRKRLGPVKGKRGCYKRKKRSETCTIESTILEDAFSWRKYGQKEILNAKFPRSYFRCTHKYTQGCKATKQVQKVELEPKMFSITYIGNHTCNTNAETPKSKTCDHHDEIFMDSEDHKSPSLSTSMKEEDNPHRHHGSSTENDLSLVWPEMVFEEDYHHQASYVNGKTSTSIDVLGSQDLMVFGGGGDFEFSENEHFSIFSSCSNLS
The following text describes a protein:
Function:
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MKLAIISTLIAGAAAFAPQTVGPSTSALSATRAGLVGALPPVGFFDPAGFAAKASPEELARYREVEIMHGRFAQMAVLGFIIPEKCAYDGAFGDDFLAPTGRALEAINTDPVWLALTLGVISALETLRLLQTEPGTRTDAKIEGLGWRPKSEAEFVNYQVRELQQGRLAMLAFAGEIAQELVNEKPLLVNLQDSGFVSW
The following text describes a protein:
Function:
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.
Subcellular Localization:
Cytoplasm.
Sequence:
MRHSLYRLCQCAKLSFTILVLAVSILSCVDVLARAQADDAAPEILYVRGCRDGAAEARETTGCFAAPAGASASSPTALVPIASVTLSLQGVHLPAEVRDTDNGDSQAVLHRVLLQEHRRPPLLGQEQSEADTRLLEKIVLSCSRPMASLVFPTQLISCELENPLLSLAGVEGMAPQLVRLVSQPMWFDVRLEERRSGEEAYRTVTVLRRAVQLRVSNTTNAKDEMAAETPRGQAEKVSWEEVRQHPLERLYAPLPASQDRAERADEPYDGDGAANGDEVWAELGIGGLKRELRTLFRRVFLSRLPSLAPLAEALQLQHVRGVILYGPPGNGKTLIARNLFRLLGPNTRLSIVNAADILSKFVGESEKNLRDVFEGYDIGTTSKEETAQQESQRFDRSAHKKSGATKKGALLVLVIDELEALFRRRGHSSDESSAKAVYDGVTNTLLSLMDGVKSRNDLLVVGLTNRLQAIDSALLRPGRFEVLIEIPAPDVPGREDIFFIHTERLRERSFLAPDVVLRDLALESGGFSGSDIAGTVRSALSYALLRYRRDGLFQGGPQSTEAGEGSSGVADAEMIGHRAGDVGGLVLEGTGGSGSMSSSASSPSLFKVTREDFERAFKDIRSAKDEASVLSHLSADGDRVSAEIVDHDGTVSTNVKRATAVIERVMQSNRTVTGMLAITGAPGTGKSTVAQALTRVYDFTTVRYLSCRRLAQLPDHEEQLGKLRDALNDASHTESGIVVLDDYDVLVGVMSSGGYAGNTLRSLLYEYMHRSGGVSRALAANSPLAAADEVGHNLAMNAESRVSADRNHRILVLTSSLSSVLQQLSFDAHLRVHPVLRRGAEALLQEYRVADPVQSVKAAAAYPVSMSYRTFLRLTDISLQRWVQEVENTAAAIGDSQSSDVGSSASTMELPAYFATSHQMRAVYNEMRARQVAANFYAVSDDAASRSFISAVRTTVADMGLMDPYQGWGGEGSDDEDGKEAAVDVDELVGAADELLW
The following text describes a protein:
Function:
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
Subcellular Localization:
Nucleus.
Sequence:
MAVVNTNNPVLFDNDDDDGPISFKRSSNSVKSSRPTPSKQEGSSGGAGVPVRSQKHVAPNQQKNGVSASVSRPMHMKPPPSSPNQRPSGSGQPNSSAAHSSKSNSNDKSKLKRPLVKEENSDDSDDDVPIGLRKKVEEKKLKRVDEKADDSDDDKPLSLKINSSKMSSNCASRPVLQKAVAKVEQPDEDSDDDKPLASRLPTNAAPKSGGNASEDSEDEKPLAARFSKVSGSGNLKLTSSSKGLNNDSNGPRNLGKRPLDNSNQTSLALKKAKPSNVSASASVKREIKADDNDNTPLAQRLKIGESSKGKPSAKNVVKKSPASMKKGIKKMKGKVKTKMMKNSQFSKTMKVPPGSGGGKKWTTLEHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYAGKPTFIENFFTDWRTLLGKNHVIKKFELCDFTPIYEWHLREKEKKKQMTTEEKKALREEKLKQEEKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIKPSDITINIGEDAPVPECPIPGERWKEVKHDNTVTWLAFWNDPISQKDFKYVFLAASSSLKGQSDKEKYEKSRKLKGYIQDIRDNYTKDFRSKDVAKRQIAVATYLIDKLALRAGNEKDEDEADTVGCCTLKVDNVTCLPPNKIQFDFLGKDSIRYFNTVEVEELVYKAIEGFRAGKKPGKDLFDQLDTTRLNAHLKDLMPGLTAKVFRTYNASITLDGILHKETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHESQMTRLNERIDDLKAQRDELKVDLSKAKKGKPLGYDKEGKQKRNLAPDAIEKKIAAIETKIEKMEMEKKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLVAKFGWAMDVDPEFRF
The following text describes a protein:
Function:
Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK. Mediates the deglutamylation of nucleotidyltransferase CGAS, leading to CGAS antiviral defense response activation. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytosol. Golgi apparatus.
Sequence:
MADKRADSGSESDADDAVVGNLNKFTVLPLGYSGKPKPGHLIFDACFECGNLGRVDYITEHEYDLFVRPDTCNPRFRVWFNFTVENTKADQRVIFNIVNFSKTKSLYREGMAPMVKSSSRTRWQRIPSKNVYYYRCPDHRKNYVMSFAFCFDKGSDLYQFSYCYPYSYTRLQTYLSAVEKRRLDFVKRELLCLSVQQRRLDLLTITSPENLDPDVKQRVVVITARVHPGETPASYVCQGLLDFLLSQHPVAKVLRDHIVFKVVPMLNPDGVYLGNYRCSLMGFDLNRHWNEPSPWAHPTLHATKQLLVDMNANPNIVVDFYVDIHAHSTLMNGFMYGNVYDDPVRYEKQAVFPKLMCSNADDFSMMNTSFNRDSVKAGTGRRFLGGILDENSLCYTLEVSFFCYTPNSSSTVVPYDEDGYMKLGRNLVKTFLDYYKLSSLITPKPAANISTLNQFRRREKSAKGSKGESGKGERRASSEMSKYYTQRNNVDSHSAPTVNGGPTVQLKFNQREARR
The following text describes a protein:
Function:
ATPase required for the genome encapsidation reaction. Part of the active packaging motor via the binding to the packaging RNA (pRNA), itself fixed to the head-tail connector at the unique portal vertex of the prohead. Binds and supercoils the pre-formed, unit-length DNA bound to gp3 to produce an initiation complex for DNA packaging. Provides the energy to actively pump the viral DNA into the prohead. Approximately one molecule of ATP is used in the packaging of 2 bp of viral DNA. ATP hydrolysis results in a conformational change that causes the arginine/lysine finger of one subunit to move into the active site of its neighbor, where it interacts with the negatively charged oxygens on the gamma-phosphate of ATP (Probable). After packaging, the ATPase and the pRNA are released from the prohead.
Domain:
The N-terminus contains the ATPase activity and the C-terminus (CTD) binds DNA. The CTD is likely a vestigial nuclease that has lost its hydrolytic capability since Phi-29 is not a concatamer that neads cleavage.
Sequence:
MDKSLFYNPQKMLSYDRILNFVIGARGIGKSYAMKVYPINRFIKYGEQFIYVRRYKPELAKVSNYFNDVAQEFPDHELVVKGRRFYIDGKLAGWAIPLSVWQSEKSNAYPNVSTIVFDEFIREKDNSNYIPNEVSALLNLMDTVFRNRERVRCICLSNAVSVVNPYFLFFNLVPDVNKRFNVYDDALIEIPDSLDFSSERRKTRFGRLIDGTEYGEMSLDNQFIGDSQVFIEKRSKDSKFVFSIVYNGFTLGVWVDVNQGLMYIDTAHDPSTKNVYTLTTDDLNENMMLITNYKNNYHLRKLASAFMNGYLRFDNQVIRNIAYELFRKMRIQ
The following text describes a protein:
Function:
Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MLGPGGTGARWPPLLLLLLLPPLWGPAGAAGLADSVIWAVNAGGEAHVDVHGIHFRKDPLEGRVGRASDYGMKLPILRSNPEDQILYQTERYNEETFGYEVPIKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNGHVVVKDLDIFDRVGHSTAHDEIIPITIKKGKLSVQGEVSTFTGKLYIEFVKGYYDNPKVCALYIMAGTVDEVPKLQPHPGLEKKEDEEDEEEYEEGSSIKKQANKNRVQSGPRTPNPYASDNSSLMFPILVAFGVFIPTLFCLCRL
The following text describes a protein:
Function:
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
Subcellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein.
Sequence:
MGPVYRSYRSAECSWAAFYIKLVNIFRYFLPILMIFLTDGLWKKTNTFREVPSVSVTGDFIVYGYGHQKSIISSSYPVLNAAASAEQFSTSQILHHFEEVNDNENNIPSFQKSNQNLHIDFQMTTQNVSINTLIYAFSLKMKLDYHSIVDAELFLIDTIHLASPTSKVQTTARLTVDQSIPFKSREKFKLIEKRRQDVQHYQIQSVIKRIAEAPISWNMERKSTLLLSAGSPPSTLSLTLFLSIPEMEFTYKTGFWELLKWFWIQYLAAYFIIDHIFASLTSYLFRNRVFYVNDVVR
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway.
Subcellular Localization:
Nucleus.
Sequence:
MADNNADWRSPAFRQKVMAQIDDAVRAAGNPTSKSSMEMENHVFQKAKSREEYLALVARLILHVRDSQTKKDQQRQGGGPQQDPMNALQNLTSLSQGQPSQQAMQMSQPSQLALQSQLAQSTQQAMQQQMSQQQQFQQQPPPQQFQQSQQPFQHSQQAFQQSQQPFQTSQQPLPPQPPQPGGQARMGPTMQQQQQQAQFQAQQRQQFQGQTRAQLVQQQIQQRLQQQQQLQQQQQQQQQQQQQQQQQQQQQQNLMQQQLQQQQLQQQQQQPALQRQQNIGGLLSPSQQLQGQSPGSVQVASPAQSSAMQRPVASPAQTSSMQRQVASPAQTTTMHRQVASPAQTGSIQRQVASPAQPGSMQRQVASPAQPGSVQRQHTPQSGSQSAASPATMLPSPSPQPSMAPSPASATARTPAGVQSPVSLNTPGNPGSVGMAASPRNPTEEQAYLEKWKQLSKYIDPLQRMIKRVSNTDASTDGQAPSTEHKKDLSKMKNLLEILTDQKKRLQYQTLLKCEQVLEKLELQMKMSHTTSTTTTTTTTTPAQLPKSQQHMCQPLLDAVASQLGSPMLNHTLKRTFGPALTALHGPPICFPGPPPKRQRIIPRQECSIPNILQGEVAKLDQKFKVSLDPTQNNISTSVHLVCRLDDRSLPSVPPIFVVVPEQYPEESPQCTAESHDYDSTSFLQTVKKSLDLRLLKLPDQHSLTQLLGAWEMSVRQACKEAVAITT
The following text describes a protein:
Function:
Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.
Subcellular Localization:
Cytoplasm.
Sequence:
MSHRNDTSNCCSFKIPRQRNWQTMGSTEQTTEILLCLSPVEVANLKEGINFFRNKSTGKDYILYKSKSRLRACKNVCKHQGGLFIKDIEDLAGRSVRCTKHNWKLDVSTMKYINPPESFCQDELVVEMDENNGLLLLELNPPNPWDSEPRSPEELDFGEVQITYLTHACMDLKLGDKRMVFDPWLIGPAFARGWWLLHEPPSDWLERLCQADLIYISHLHSDHLSYPTLKKLAGRRPDIPIYVGNTERPVFWNLNQSGVQLTNINVVPFGIWQQVDKNLRFMILMDGVHPEMDTCIIVEYKGHKILNTVDCTRPNGGRLPTKVALMMSDFAGGASGFPMTFSGGKFTEEWKAQFIKTERKKLLNYKAQLVKNLQPRIYCPFAGYFVESHPSDKYIKETNTKNDPNELNNLIKKNSDVITWTPRPGATLDLGRMLKDPTDSKGIIEPPEGTKIYKDSWDFEPYLEILNAAVGDEIFLHSSWIKEYFTWAGFKDYNLVVRMIETDEDFNPFPGGYDYLVDFLDLSFPKERPQREHPYEEIRSRVDVIRHVVKNGLLWDELYIGFQTRLQRDPDIYHHLFWNHFQIKLPLTPPNWRSFLTCCEQNGPGISQVAEEDHIEPLRPAH
The following text describes a protein:
Function:
Required for efficient transcription initiation by RNA polymerase I. Interacts with Pol I in the absence of template DNA and stimulates recruitment of Pol I, but does not remain as part of stable preinitiation complex.
Miscellaneous:
MISCELLANEOUS: Present with 138 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MMAFENTSKRPPQDFVAPIDQKKRKVQFSDSTGLVTLQPEEIKDEVFSAAMYSRFVKSALDDLDKNDSTQIGIIANQVALPSKNPERINDKNLNILLDILSSNINRIESSRGTFLIQSIINFEKWWELPPHTLSKYIYFIKILCSSIPKWWQDVSMILVSCFILPIKQTVCHHDMLKYFLRMIPSSMGFIDTYLAKFFPNKNDTRRKLVNYTSNLLKLRGYCSELGFQIWSLLIEKIISIDVELQNELDELDDDVDDDDLEEVDLEDDDDLDDDSGDDDDENCGNSNEELRSGAADGSQSDSEDMDIIEGMDGTEEYNVELTQGIKELSTKLDSILTLVSTHVEEQVTPESLESGEGVGVFNTLTTLFKTHVLPTYYTRSIQYIMFHVSQQQLELMDSFLVTLIDISFAVNEAAEKKIKSLQYLGSYIARAKKLSRTQIIFVASYLTSWLNRYVIEREEEVDQRGGMERFKHFYAAFQALCYIFCFRHNIFRDTDGNWECELDKFFQRMVISKFNPLKFCNENVMLMFARIAQQESVAYCFSIIENNNNERLRGIIGKADSDKKENSAQANTTSSSWSLATRQQFIDLQSYFPYDPLFLKNYKILMKEYYIEWSEASGEYESDGSDD
The following text describes a protein:
Function:
May be involved in vacuolar sorting and osmoregulation.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MINPISFRPGPVTFWTTLIYLALLIPIVIINEKTPAAPKTAEPFKGVNLTEAWLDLTTITRAYHPYNSKFNEEVRRYLLEKVETILEENGASWVSDGQMTTVKDGKSAAVTVFDDNVSNSTFVMGKSNGTTFTRTDSINNAAYFEGTNILVYIRGKEDDEGEWWEADYAHGMRRNAKGLTLVNAHYDSVSTGFGATDDGMGVVTALQVLKYFTAPGHQPQRGIVVMLNNGEEDWLYGAHALGQHKLNPFIHTFLNLEGAGAGGRAIVFRATDREVMAAYARTSHPFGTVIASDAFGLGFISSGTDYSVLVDAYGQRGIDLAFFKPRARYHTNQDDTRHTSKGSLWHMLSAAIHTTKQFSGDTGNTFIGQRPDKAHGKVANGRSSNGVWFDLFGKSFVLFGLRGMFAWSLTLLIATPLVLVGITWLLRNLDKDYFFTSTVKTKEHPEYEAVPIGGWKGFFRFPFALGVAVFFTISSALLMNKVNPLIVYSSRYSVWVMMVSIFYFSFWMIMRGANFVRPSALHRGYANLWLFVFGWIVLVAVTALEDRRRIAAGYIFVFLESAIFLSCLISFVELLAVPRKSSYALQVQEDYDGQEHDHNGYQGFRDSTDEPSLRARAESSASAASPPSPTVAQEPSKSKAPAGTTNGLSTAPSVAAHSSQPQPAPTTPIPGRSSGAPSTASRDENESEDDDEPTERTPLVGGNGTNDRGRTTFATTYRRSITALVHGARKMEEDGEPYDHEQEWSGHLPSWAWFFQFLLLGPFMIILAAQTGLMLTDAVYQTGSDGSKLITPYLIIFVFTVLLILPLTPFIHRVTHHIPVFLLVVFIVTLTYNLIAFPFSANNRYKTFFGQYIDVATGDNKVCYTGIEEYVRPIIAELPSASGREVTCGKSLRRGSTISTCCFDGSAVPPKLGSEDDNGLPEDSYADLITINATRSTKRGDSSRTTARIEITADNTKSCFLQFKKPVSALAIENGSGWDDRFGQYPEDGVGLVRLWHREFGKTWVVNAEWKGSETRKEYDENDGTVICMWSDANTPGTIPALDEALQFVPSWAAVTKFSEGLVEGRKAFKIV
The following text describes a protein:
Function:
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
YNFGISTASSLLDASEYPLLRFSIASRIFSPRIEVHRQISKKFQPNSCKNTFFVYGNQVGCQLSELNFKEYSGNAEIFEFDHIFPMKSKANRTLIIYGVLGTAELKNMILEAKILVETRENLNFALRFLSLSSGTTKVSLSGYGVELALKNTEYKAVDHLTQELPENLHGLNFRILKNRHTDRHNELESLRENLEKLGEIVPLKQWQLKDLGLKTCERIQEDSMELEEIERVLQDFPIHARTISHRSLNESFTKPIQKFQKTLKSAGIGNGENLLALNGRILSKSDSKIDLFELIERKTEKKVMDRLIEIGSVSEDSEIDYSKLLTLFDFSPIAISKNAFDYRKTKPVFLNDLESFLSPYRSLHLLLQPFPSDQIRPIARNIFNLILFIDPFDSEDKLLDLAQKYLKGKVFIRIGLVPFFNENKWGVSVQEGVNSKEISKEARKIWKTNEDILKALKNGNEFLLKTGLGKGPQALLNGYPLDTSSSESFDAALFDNIQKQTLRLQLALYQRLITDSVKIDDFWLKEETNPDLKTRVSMRIFSAKFEFFRIVKAFNERRFVELDSEASENPENPTLAIIANFENTKNRLSITKWLKSLKFPLKIALISNPTTSSDSEDSSCPSDSENLESAILRLENQESCIGARKFSNFLRKNEIKAGEMAVIFNGLVIGPFEENEKEQFLEIEDFEFLENLWKERGAKKTSAFLSQHFPNQDDVTIKFFSVLSKIYKKDVPRVAFDNFKDLENRNLIIFPPKNPESPYSTITWILNPVSREAQHLVSIVKLMSNVLNAKVEIIFNPSSELHEMPIKRFYRFVASEFLEFDENGKIKDQSAIFSNLPQKQLLTMSVETNDGWMIEVKKADDDLDNILLENTSGDVESEFSLEHILVEGQSQKSGTGDASDGLELELKSENTKYDTIVMRNLGYFQLKAEPGIWDLKIRNGTSSENFWIQKIDSKEVNGKITVVVDSFTRKWTQLVVEEIEDKKEQKEGSAMGRLMEKAKNFFSTPPPSETINVFSLASGHLYERFMRIMIVSVMKNTQSGKVKFWLLKNYLSPKFKESIPILADFYGFEYELVEYKWPKWLHQQTEKQRVMWGYKILFLDVLFPLNVDKIIFVDADQVVRADLLELMDFDLKGSPYGYVPFCESRKEMDGFRFWKTGYWNTHLMGRRYHISALYVVDLKAFRKFAAGDRLRGRYDNLSADPNSLSNLDQDLPNNMIHEVPIKSLPQNWLWCETWCDDRSKKTAKTIDLCNNPLTKEPKLSSAQRIIGEWKELDEEISNVI
The following text describes a protein:
Function:
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Subcellular Localization:
Nucleus.
Sequence:
MNNKIRKSIENNNNNNDDDDDDNNKKLKIEKEEKEEKEEEIKIINSFILKSPIGALKITADDKSLHGIRLYESKNLDEECKNKTNNKIILQINQELDQYFNGKLQEFKTPINLELGTEFQRKVWTHLRTIPYGSTLSYSSVATQLGLDKKYARAIATSCRLNIFLLLVPCHRIISSNGKVIGYSGKKGIDKQFILSNIEKANIKT
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(3) position of uridine 2634 (m3U2634) in 25S rRNA.
Miscellaneous:
MISCELLANEOUS: Present with 2960 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MARKLKGKIGSKGLKGALLRHKAKVKLVRNIESKQKHELRKKNSSANNKTVKRNQEFQKLNQGKVMPFEKDETLMLCGEGDFSFARSIVEQNYIESDNLIITSYDNSVNELKLKYPHTFEENYQYLKDLNIPIFFQIDVTKLVKSFKISKNNTWFKIINRLSDHRWGNKPLQNIVFNFPHNGKGIKDQERNIREHQDLIFNFFQNSLQLFNLINTKIQNDTLRYTQGYDLNEDTPQAKKLTAEGYGNIILSLFDGEPYDSWQIKLLAKKNGLTLSRSSKFQWENFPGYHHRRTNSEQDTTKPAKERDARFYIFSKYVSNSSKHNRKSKKDTDSDSD
The following text describes a protein:
Function:
Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
Sequence:
MPSFTEARSIILDRVAPLGVERVGILEAVGRVLAENLIAPWEMPLCDNSAMDGFAVRADDCGETPVSLKVTGYIPAGGRPAGPVEPGCAIRIMTGAPVPSGCDAVVPVEETEDEGDAVRIMATVARRQHIRFKGEDVATGDIVVPRGTLLQPPEISMLASFGKALVPVFRKARVAILSTGDELVELGESPAPGTIINSNALSLAAAVRQCGAEPVIIGIARDNRESHREKLAEGLKADVLITSAGVSAGDRDLVRDVLAELGAEQLFWKVDMKPGGPTAFSMHGPVPVFSLPGNPVSTMITFEFFVRPALLRMMGHSRVVRPFVKATLLEEARKKPGKVNFLRVQATERDGRLVASTAGEQHTGILRTMVNANALVLLPREASVVPAGSEVEMMILRDDVTMLER
The following text describes a protein:
Function:
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MPPKLSKSAKQGLIVSHLRSTRTCHTLKDLEKMLPSVASINSIQVKDYIKELTDEGRIRVEKIGSGNWYWCFGGDEVKERERQLVQLRKEVERVQASCKRAEADSAVRKEQRDKEFGQGGEEEWNELMERKKALEEERNRLLTEWATISTTGEGKSVGQMKDEMEESRQRAQMWTDNIYLLEEYVRKLTGGDRDLMQAVQRECYGDEYVEGEGLRELDWST
The following text describes a protein:
Function:
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MHRIQVVKRVDRLVCQPFPSTCVGRTHLFKPPVGFYRMKSGASSSSDGKPAEQDEKLHPIFSTNKTAPLPSFKTDPYPIPLQNPAHPTTQTDTTQSYSVNQEIYHQIDQLKQVEDKHAESYDDALSASTIDKLRSRLVYQSRKRGIVEIELLLSTFIEAQRWLKDWDLKQLTQYSRLLMLPDWDLYYYLVKKQEPPSDSEFFKSDLLDQLRIHTSNSSKTVRIMPSLHS
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Sequence:
MLELRSVNAGYGTFQALFDVDLDVRAGEAVGVIGPNGAGKTTLMRVISGLIRPSRGSIRMEGVDVVATPPHKIVSLGIAHVPENRRLFPQLTVDDNLKMGAFMKEARGHYAERLEVVFDLFPRLKERRHQMAGTMSGGEQQMCAIGRALMSNPKLLLLDEPSAGLAPVVVQQVFELVKRIRARGLTVLIVEQNVQQVLRVVDRAYLIEAGTIRSSGTSAEMLASDTVKEAYLGV