lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Formation of pseudouridines at positions 38 and 39 in the anticodon stem and loop of transfer RNAs.
Miscellaneous:
MISCELLANEOUS: Present with 5860 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSNFIRRLVGKMKAISTGTNAIVSKKDSIYANWSKEQLIRRITELENANKPHSEKFQHIEDNKKRKISQEEVTRSKAKKAPKKFDFSKHNTRFIALRFAYLGWNYNGLAVQKEYTPLPTVEGTILEAMNKCKLVPSMVLQDYKFSRCGRTDKGVSAMNQVISLEVRSNLTDEEQRDPTNDSREIPYVHVLNQLLPDDIRISAVCLRPPPNFDARFSCVHRHYKYIFNGKNLNIEKMSKAASYFVGERDFRNFCKLDGSKQITNFKRTIISSKILPLSETFYCFDLVGSAFLWHQVRCMMAILFLVGQSLEVPEIVLRLTDIEKTPQRPVYEMANDIPLLLYDCKFPEMDWQEPTVDDYKAIKFTTATEALTLHYELKAAVCNIFKDVLPTANTNNFSKTIINLGDGRGKVVGTYVKLEDRSVMEPVEVVNAKYSKKKNNKNK
The following text describes a protein:
Function:
Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. Repressor of entry into mitosis that is activated by chromosome breaks.
Sequence:
MEFTVSNVNLRDLARIFTNLSRIDDAVNWEINKNQIEITCLNSSRSGFSMVTLKKAFFDKYIFQPDSVLLTGLMTPTIRIRTQVKPILSVFRNKIFDFIPTVVTTNSKNGYGSESASRKDVIVENVQISISTGSECRIIFKFLCKHGVIKTYKISYEQTQTLHAVFDKSLSHNNFQINSKILKDLTEHFGQRTEELTIQPLQERVLLTSFTEEVVHNRDILKQPTQTTVSIDGKEFERVALNEGVSVTLSLREFRAAVILAEALGSSICAYYGVPGKPILLTFAKGKNSEIEAQFILATVVGSDEQEVSSMMGNRWQHSSTPASLFNSVERNNSLTAVAHNPPGSIGWQTDQSDSSRMFNSALDRSDETNGIKEPSTTNDAGQSLFLDGIPNESELAAFNNDVNDDAEFGPTQAEQSYHGIFSQED
The following text describes a protein:
Function:
RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. Binds to the 5' side of the stem-loop structure of histone pre-mRNAs.
Sequence:
MACRPRSPPRYGSRRDGGASPRSPARWSLGRKRRADGRDRKPEDSEEGELQTADHRPESFTTPEGHKPRSRCSDWASAVEEDEMRTRVNKEIARYKRKLLINDFGRERKSSSGSSDSKESVSSVPADVETDESVLMRRQKQINYGKNTMAYDRYIKEVPRHLRQPGIHPRTPNKFKKYSRRSWDQQIKLWKVALHFWDPPAEEGCDLQEIQPVDLGEMETEFTESSSESQTSSQDNFDVYAGTPTKVRHVDCQVEDEFDLEACLTEPLKDFSAMS
The following text describes a protein:
Function:
Fatty-acid-binding protein. Interacts with most fatty acids tested and has maximal relative affinity for C16:0.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MDGILAAVPSAVCVSLRISCRNLDNAESIYHFPGKSLNRVSVLQTGNYVSRKGNSLLKNRHCGEISRVIVKSAASSVGNAEDYAEETATSVKFKRSVTLPGCSSPLSLLGTGFREKKFAIIGVKVYAAGYYVNESILSGLSAWTGRSADEIQRDSSLFVSIFQAQAEKSLQIVLVRDVDGKTFWDALDEAISPRIKSPSSEDTTALSTFRGIFQNRPLNKGSVILLTWINTSNMLVSVSSGGLPTNVDATIESGNVTSALFDVFFGDSPVSPTLKSSVANQLAMTLV
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane. Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes. Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA. SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER. Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Domain:
The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins; The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.
Sequence:
MVLAELGGRITHAIHQMRNATIIDEKALNECLNEITRALLQSDVSFSLVKEMQTNIKKIVNLQDLSAGHNKRRIIEQAIFSELCKMLDPGKPAFSPKKTKPSIVMFVGLQGAGKTTTCTKYAYYHQKKGYKPALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKENCDLIIVDTSGRHKQEASLFEEMRQVAEATKPDLVIFVMDSSIGQAAFDQAQAFRQSVAVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDQFEVFDVKPFVNRLLGMGDLSGLVDKLQEVVPKDQQAEFVEKISKGNFSMRMMYEQYQSVLSSGPLNQLYSMLPGVSAQMMPEGESEAKIKRYMTVMDSMTNEELDSSNLKAFNESRIMRIARGSGRIVREVMEVLEEYRKMAKTFSNWKGFKMPKNGDMSSNKSAQQLMSKVMSPQMLQRFGGMSGLQSLMRQMGTNI
The following text describes a protein:
Function:
An integral component of the septate junction. May play a role in cell-cell interactions that are necessary for proper development. Vital for embryonic development.
Subcellular Localization:
Cell junction, septate junction. Note=Septate junction in the apical-lateral domain of epithelial cells during embryonic and imaginal disk development.
Sequence:
MPAEIKPSAPAEPETPTKSKPKSSSSSHGKPALARVTLLDGSLLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLDLEKPVSKFFRTDTWPLTFAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLGSYLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHKGQSPAEAELHYLENAKKLAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGEFEQYESTIGFKLANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKMFPVFGSTYRYKGRTQAESTNTPVDRTPPKFNRTLSGARLTSRSMDALALAEKEKVARKSSTLDHRGDRNADGDAHSRSPIKNKKEKDADKEAKLREKKQKEKEEKERKEREKRELEEKKKAEKAAKAALAAGAAAGAAVNGNDELNDSNKSDKSSGRRGVGIFSSGRKSKSGSPSKDGKDKSGKDKDKEVGRLGLVVTSGLGDNQQDQNLDEAARNAAKNRGSTTPGVTRQYEYAVDNDGNTSPTRKSYTPGGFRYDQDPNSRKSGADGQEQLSPTSQQKKIGLAFNYAPGNENALKETAEKLKAGQLSPRTQDKLNRGQLSPKSRAKLLQDPLLSPTTRAKLQGSAVDAAAVPLSDSQKRSYSPTKGPQGYSSGAPGSYKPISDPTADFLESQRYNKEPGYVGPSKADVAAGLAGAAGSKKPGSPTKTGKGAPGAAAAAAAGAAGAAAAAAKPKKRRVKIMVITSKFDPSTKRIDAENGSIEHSTGILDPATGLIDTKYGVIDPKKGTLEALNTKTGKKEVFQGDVDGKTGNLHLVSGVADPKTGRLDDTLGQIVCITPQDNPVVELTVITSRIDPATGKIDTVNGDVERSLGVLNLDTGLLDTKYGEINTRTGELKAIDPKSGKIVVSKNVKVDPGTGQITILGIVDPKTNKIDPNQGRLIEVGQQIDPIVEVTSLAGKFDSKRNIIDPKTAQVETSGGQFDPKAGKIDTKYGQIDLVKHTITFNDPKSGKTVTRDIKIEPTTGQIVLKNQVNPKNNKPDKDYARIISLRIVQQRVDPATKAPITEVSASKDKDIVVDPKSNQIWVPTGATDPATKEQQYISSSVDPKTGYVITIYGYLDPKTNEIKKQTKLDPNTIKIEPTSGKIYTATGEVDQATGEPLYAATQVDPESGEVYTKLARVDPKTGKIVIVRILLISKTDERGRPEEIDPSTCEIDPVSGRVLKFFNKTVYVYNMIDPVTGEIVQVDPNDPRFAGARTTVTHTMTLTGEIDPVTGRIKSEYGDIDPNTGDIDPATAVTDPVTGKLILNYAQIDPSHFGKQAQVQTTTETVPITRQQFFDGVKHISKGALRRDSEGSSDDDMTAQYGADQVNEILIGSPAGQAGGKLGKPVSTPTVVKTTTKQVLTKNIDGVTHNVEEEVRNLGTGEVTYSTQEHKADATPTDLSGAYVTATAVTTRTATTHEDLGKNAKTEQLEEKTVATTRTHDPNKQQQRVVTQEVKTTATVTSGDQYQRRDSVSSTSSGDSGTPIDGPYDGASVVRTDNQKSPLFTTSATTGPHVESTRVVLGEDTPGFSGHGEIISTQTVSSKTRTVETITYKTERDGIVETRVEQKITIQSDGDPIDHDKALAEAIQEATAMNPDMTVEKIEIQQQTQ
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MTFNIKGKWQSIAIDCEEGIELDQLQGLVSFEELTDYTITDGTGKVSEVTNRSKNKSVKKTPKKDANKVEEESTVENPHDDGKDNVNMKAWDSLQVPEPVLKALSDMNFLTPTPIQSLSLVAAIRDRKDIIGAAETGSGKTLAYGIPIIQRILQLKADGKKSSKRKWDKANNKTEVIKETPSKKRKHEKGAKPTSSTSDQKSSNKTTVDNMDNSEVAESPVYALVLTPTRELALQVRDHLRSAAKYTDLKIEAIVGGISQHKQQRLLNYQPEIIIATPGRMWQLLSEGESHLQTINKLPLLVLDEVDRMIEYGHYAELSDILERLPERPLRQTLVYSATLTINKNKKVEMKKSVKKKLSNEKTFDALIEKLKLDKKVKVINLIEKDITVETLVEARINCMVDDKLSCLYLFCLLFPGKTLVFANSVSCIKKVVDIFRLLEQPAYPLHAKMQQRQRLKNLDRFKSSPSGILFCTDVAARGIDIKDIKYVIHFELPKAAELYVHRCGRTARAASEDIPEFPLDRSFERDVKRRMVLAERIVSLEKTYVYNTAIIACGIRNTRMRNYKVINLLMDVYYRMTEMLTTQLKLPLTTRNFSGNFPATNEILSTPRSDDPITPNKDDSIAGIEALKKKNKRKTAARRDDSIVGIEALKKKNKRKTVTRRDDSIAGIRALKKKKKQKTAFKKK
The following text describes a protein:
Function:
Component of the DSC E3 ubiquitin ligase complex which is required for the sre1 transcriptional activator proteolytic cleavage to release the soluble transcription factor from the membrane in low oxygen or sterol conditions. The complex also plays an important role in the multivesicular body (MVB) pathway and functions in a post-endoplasmic reticulum pathway for protein degradation.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MDTIVLDQRGEVFSFFRSLDMLCYAIIAQQYFQDPTVLLLLLKVFVQLSYLTPKPFSQLNALPLFYPLLLNFLISLMVRMFFNLPTAGESLDGYLYGGSIINFIGEKNESSRIDFITSDLVLFCLQIFMALILIASNKRPTQASHIQASQSGLSNVDGDEEPSDLITEDSRDTQQGQRQEDLQRQLENERSRLIARFSHSLYSFQHGLSFGSPQNRNTPLQRQSADSYSTPVCIEVDSEDWKDLVWKSQYATENANTNSINNSPLSSNTTGVPNSVLTNPI
The following text describes a protein:
Function:
Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDVENEQILNVNPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINARAKRRLRKNSSRDSGRGDSVSDNGSEGLRCGVSAPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVRDPNYDDDQENCVYETVVLPLDEMAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDMSEAEHCLKELEVPHFHHELVYEAIVMVLESTGESTFKMILDLLKSLWKSSTITLDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEDCFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY
The following text describes a protein:
Function:
Essential member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) and spt-5.
Subcellular Localization:
Nucleus.
Sequence:
MSAQNYHAGLHQSSTQRPPKRPNTEHAQEPPKRALIGGQTTPSSSGGGQTPNGTNYELEVKQQLSNYQKLFDQATYPFIRDVSTYEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLWSAMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPFGKNVKQHDSATDDDALHLLEILLAIDPDKRPTSDEAEDDIWFFKDPVPMANVQDLMDTIPNSQFEYTVGKGAHANRGRHQNAQQRPNQQQARPSNAIPAGQYRDTIF
The following text describes a protein:
Function:
Beta-glucosidase acting as a preformed defense system. Hydrolyzes the bisdesmosides avenacosides A and B to 26-desgluco-avenacosides exhibiting fungicidal activity. Can use beta-fucoside > beta-glucoside > beta-galactoside > beta-xyloside as substrates, but not alpha-glycosides, beta-thioglucosides and disaccharides.
Miscellaneous:
MISCELLANEOUS: Long fibrillar homomultimers are formed by linear stacking of trimeric units. The multimerization of the enzyme promotes formation of a long central channel with narrow openings at the sides. The active sites are localized inside the tunnels, constraining the accessibility of substrates and products.
Subcellular Localization:
Plastid, chloroplast stroma. Note=Found in a fibrillar spherulite called stromacentre.
Sequence:
MALLCSALSNSTHPSFRSHIGANSENLWHLSADPAQKSKRRCNLTLSSRAARISSALESAKQVKPWQVPKRDWFPPEFMFGAASAAYQIEGAWNEGGKGPSSWDNFCHSHPDRIMDKSNADVAANSYYMYKEDVRMLKEIGMDSYRFSISWPRILPKGTLDGGINHEGIQYYNDLLDCLIENGIKPYITLFHWDTPQALADEYKDFLDRRIVKDYTDYATVCFEHFGDKVKNWFTFNEPHSFCGLGYGTGLHAPGARCSAGMTCVIPEEDALRNPYIVGHNLLLAHAETVDVYNKFYKGDDGQIGMVLDVMAYEPYGNNFLDQQAQERAIDFHIGWFLEPMVRGDYPFSMRSLVGDRLPFFTKSEQEKLVSSYDFVGINYYTSRFAKHIDISPEFIPKINTDDVYSNPEVNDSNGIPIGPDVGMYFIYSYPKGLKNILLRMKEKYGNPPIYITENGTADMDGWGNPPMTDPLDDPLRIEYLQQHMTAIKEAIDLGRRTLRGHFTWSLIDNFEWSLGYLSRFGIVYIDRNDGCKRIMKKSAKWLKEFNGATKKLNNKILGASSCCSGVTHGGGTA
The following text describes a protein:
Function:
Chromatin regulator which modulates histone acetylation and gene expression in neural precursor cells. May recruit histone deacetylases (HDACs) to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. Has a role in proliferation and development of cortical neural precursors. May also regulate bone homeostasis.
Subcellular Localization:
Nucleus.
Sequence:
MSGCVYVVPVIYRASTQTLEDKDKVSLTKTPKLDRSDGGKEVRERATKRKLPFTVGANGEQKDSDTEKQGPERKRIKKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTDSSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKTVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYTKNNTIAPKKATHRILSDTSDEEDLSVTVGTGEKLRLSAHTILPSNKTREPSNSKQQKEKNKVKKKRKKETKGKEVRFGKRSDKFCSSESESESSGSGEDDGDSVGSPGCLKESPLVLKDPSLFSSLSASSTSSHGSSTAQKQNPSHTDQHAKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDCSSEGSSVESLKPVRKKQEHRKRGALSEKKNCFHSSVDGAIPKLDKEGKVVKKHKTKHKHKNKERGLCSVSQELKLKSFTYEYEDSKQRSDKAILLDNDISTENKLKVLKHDRDHFKKEEKLSKMKSDDKEWLFKDEIIKASKDDKSLRRVRDMNKDVSRPFRDEKDRSNKVEKEKSAKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDFKEDKISKEKEKTFKEDKEKLKKEKVYREDSAFDDYCNKSQFLENEDTKFSLSDDQQDRWFSDLSDSSFDFKGEDSWDSPVTDYRDIKNDSVARLILETVKEDSKEKKRESRTREKRDYSEKRSDKDAFFRKKDRDYLDKNSEKRKDQIEKHKSIASYLSEKDKKRRESAEGGRDRKDRDLSDICRDRKDPLEGAKERKDGRAKPEEAHREDLKEYSCESIFKDRSDCDFGKNLEPWERHHSVREKEKRDGLEKEKREKIKLEKYRDKSSDKDKNEKSLLEKCQKEKEFDKCFKEKKDTKEKHKDTHSKDKERKASFDQVKEKKEKCFSGIISEDFSEKKDEKKGKEKSWYIADIFTDESEDEKDEYPASGFKIGEAGEVQRVDGLQEKDDGREPHPSDRHRKHSVDRQHSEKPKEKEPKEKRRDRGAMEGVKDKKEKAFDKHKEKKDKESTDKYKDRKDRASVDSTQERKSRQKPPEKAEKKPCAEDKAKSRHRERPDKEHGRERKASKGVELERSLLEKLEEEALRECREDSNDRASEVSSDSFTDRGQDPGLSALLDTSVTEPPEEKVKESCPQEKLKEKERHRHSSSSSKKSHDRERGKKEKSERKDKGEDYKETGSRRDSSQCEKEFLDADAYSISYNTKADIEDELDKTIEFFSTEKKDKNDSEREPSKKVEKELKPYGSGTINILKEKKRREKHREKWRDEKEKHRDKHGDGILKHARDEHKSAAKDKDSPPGSLRERPRDESLRPSEAKLKEKSKENPEKEKADSVKLSNGSDKLPPSKDVGRKDVRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKERVKSAEDMRKKSLDVPPKKPLGLDPALKDKKLKEAAPPPPAAENKPHLGPAVDARDWLAGPHMKEVLPASPRPDQNRPTGVPTPASVVSCPSYEEAMHTPRTPSCSTDDYPDLGFDCTDPPPISSTSASACSPSFFDRFSGAASGISETPSQTPTRPVCTNLYRSVSVDIRRTPEAEFSVGDKLFRQQSVPTASSFDSPGQLLEDKAPVAPGPAEKFACLSPGYYSPDYGIPSPKADGLHCPPAAVVNVTPSPEGAFSGLQAKSPPSHRDELLAPSMEGALPPDLGIPLEATEDQQATAAIIPPEPSYLEPLDEGPFSTVITEEPVEWAHPAASEQGLSSSLIGTAPENPVSWPVGSDLLLKSPQRFSESPKHFCPAASLHPAAPGPFGATEPPYPGSPASYPLSGTEPGLEEVRDTAVEAIPAAVSPSEEPTPFTPPSRLESFFSSCKSLPEAPPEGPPEPACVTTVAQVEALGPLENNFLENGHNLPVLGQVEPVPWSDPFTTPVDDLDLGPFSLPELPLQTKDVSDVETEPVEDSPLIPPENTPAGAPMVLNGGDVAASAAEEQLVLPPDQPVTRLPAEPEPLEEPKPAMMLNATAEAGAVSEARAPEDSNSSLGPVPALPEQLPPGGGDEEAECQDPSAVSHGAPDPPVDCLAEADGAGPHDTAGLEGPPSSVLPEATEPEPKPTAEAPKAPKVEEIPQRMTRNRAQMLANQNKQSSPPSEKEPAPAPRAKGRGSEEEDPQAQHPRKRRFQRSSQQLQQHMNTSTQQTREVIQQTLAAIVDAIKLDDIEPYHSDRSNPYFEYLQIRKKIEEKRKILCYISPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA
The following text describes a protein:
Function:
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Sequence:
MFLHVCQTCLLSFAIAFSLLLLLASNTDAAGGERVVGKNGVVATDETECSKIGRDVLKRGGHAVDAAVAAAFCLGVVNPANSGLGGGGFMLVRSSKGNAKVFDMRETAPGRASKDMFTERFSEYQTGPLSIAVPGQLAGLYTAHKQYGKIPWESLVKPAENLARKGFLISSSLFKTMDSMKSTIMADEELRTIFAPNGSLLPEGKPVNFRKLADTLAAISKNGMKIFYNGSIAQKLAEDIQNAGGIIKKEDFQKYEVITRKPLVAHAFGYEIVTAPPPTSGGAMLILILKILSNYQKTTSVSNSLGKHRFVEALKYALAMRMKLGDPRFVNVTNVLKNMISTKYAKLLKDRINDNQTYEPVRYGSKWSQIYDHGTTHLCAVDSQRNAVSMTMSLNSYFGSRVMSYSTGIYLNNQMYDFSIPTLSSPPPSPANFIQPFKRPLSSMTPTILVKGGRLKAVIGAAGGLLIPDAVTQVLINNLNLKMDTLTAVNAPRLYHTLYPNVLYHEVYSRNGSDYYFDSNIVKELEKKGHVLREASSGWTVCQFVVQSSKGSNSGQLIAVSDQRKGGFPAGY
The following text describes a protein:
Function:
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).
Subcellular Localization:
Secreted.
Sequence:
IHNRENRGALEILIMKFVALTLALLFAGAQARFLWQADAPPSQLEQVRQALTLYAAQVHETAKKAIEQLEGTEFGQQYKLQLSQSLDSLQSYSKQASETLRPYGDVVSSTVLEATKTFRERLMADLEDLRKQVEPHREEVRKTLQAHLDQYREKLEPIFQEELKKGQERIEELKKKVEPVAEELREKVKANVEEMKTKLTPIVEAVRAKLTERLEELRKVAAPYAEEYRSKLGDAVSEVREKVGPMAQNLREKLEPYKEDLSAKLSALWETLAQSLKQTGGTCFPWRSSALGV
The following text describes a protein:
Function:
Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MHALLLLLLLALGSALRSPQPPEARAKLCGHHLVRALVRVCGGPRWSPEATQPVDTRDRELLQWLEQRHLLHALVADADPALDPDPALDPQLPHQASQRQRRSVATNAVHRCCLTGCTQQDLLGLCPH
The following text describes a protein:
Function:
Catalyzes the release of fatty acids from lysophospholipids.
Sequence:
MHLSSSLASPHVARLTMGATGVYRLRWTVPPAALGLLGSGVLYKTAGRNNQSLQSDSKAYFSVSSVLNANERSKRKSAGSSGAGDEDSTQYAETGLWANIIQKFDGVKQTVGNAEWIELESIKKSIIPDWTSLLPVTVQKLQRELSMAPGSLAEEIWKEAHDPDVHPEILQEARVRVGNTLCDEELAFRRKRQQHAVKALASYLNIPEEDIHPDDVPIIAMCGSGGGLRALVAGTGSYLAAQEVGLWDCVTYTAGVSGSCWLQTLYHSSITGRDYNRLVDHLKNRLGVHIAFPPKALNLLTTAPTNKYLLSGLVEKLKGDPGADFGLVDIYGMLLAARLLVPKGELGVSHQDLKLSNQRYNLYNGAHPMPIYTAVRHEIPVLEAVEDEEPKKEITPEKLIKASQREAWFQWFEFTPFEFFCEELGAGIPTWALGRHFNGGHNVVPHGEYPLPEMRVPGLMGVWGSAFCATLSHYYKEVRPLLRGIVGFGGIDSLIQGKSKDLIRVHPIDPATIPNYVLGMKGQLPPSCPESIFQSEYLRLMDAGMSNNLPIYPLLRPGRDVDIIVAFDASADIKQENWLSVVDGYARQRGIKGWPLGAGWPKEDISLKETEEMLREPQTITQDEVDEKMVDARRNSPQDNEDGVGKSHSMEPPIGSKAGDDRPSPQDTDLSYCNVWVGTKQERVSGKEPPPSKRLFHPHHGNDSEADFHLMHPDAGIAVVYFPLLPNPTAPELPPSSSMSKQPVPAQQSETTSSANVKDGARPLTPHPSTINPEVDDFLSTWNFVYTPEQIDSVIGLAKANFTQGEEQVKRVVRGVYERKKSDRLRREERAHRGRLEGFVPI
The following text describes a protein:
Function:
A beta subtype methylase that recognizes the double-stranded sequence 5'-GTAC-3', methylates C-4 on both strands, and protects the DNA from cleavage by the MjaV endonuclease.
Sequence:
MEINKIYCMDCLEGMKQLKDKTVDVVVTSPPYNIGIKYNKYSDNLSREDYLNWIEEVVKEIKRVLKDDGSFFINVGYTAKDPWIAFDVANVIRKHFKLQNTIHWVKSIAIQKEDVGNYPNIIGDIAVGHYKPINSDRFLSIMHEYIFHFTKNGNVKLDKLAIGVPYQDKSNIKRFNRKGDLRDRGNTWFIPYETIQSKEKERPHPATFPPKLPEMCIKLHGVKKTNLVLDPFMGIGSTAIACIRLGIDYIGFEIDEYYCRVAEERIKKELLKTDGKFDNVKNKNIITLDAFI
The following text describes a protein:
Function:
Involved in mRNA processing.
Subcellular Localization:
Nucleus.
Sequence:
MSAEEADKTTTTDASAGDEEEEWLYGDEGESKETEEEEAKLTAAISATSTTPVAEDAPTTTNNSSDSATPPTTTTTTGNGVASQEEAPGEDEDSESDSDDDDDDVRVTIGDIKTGAPQYTGYGGTPVNLNIKSAGSRAYGAGAKVKGVDLEAPGSINGVPVLEADMESFEEKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRLRMGLDVLNIGSTTSKISVQQGRTGNNEKEITIPAHASKAEFTSPSNLYKAGLNQGRISPPHWAGPPSQDLSYYTKTPGTIDVIGGQTATISRVEGRRRHNLEGNNIQVISEHSSSEVEPEVQKMPPPFFPPGPLPPNIPPPPFLPPPVSQAPPLIPPHRMPITVPPPNFPPPTGGPPPSLIPTLDNSGHPGGYDGRPVAPYPFPTGGFPPPMQGAVNPWPGLMENPKQWDYYPRRDKEREKERERERQRDRGHERDHSPNAGPYNSMAMCSDEERYRSYRDYGDRGYERHRERASREKEERHGGRRHREKEEGRHKSSRSSSRRRHESEEGDSHRRHKHKKSKRSKEGKEPSEERSADQENQEAME
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
Subcellular Localization:
Cytoplasm.
Sequence:
MSLINTQVQPFKANAYHNGNFIEVTEASLKGKWSVLIFMPAAFTFNCPTEVEDAADNYAAFQKAGAEVYIVTTDTHFSHKVWHETSPAVGKAQFPLIGDPAHKLTRAFGVHIEEEGLALRGTFIINPEGVIKTLEIHDNSIARDVTETLRKLTAAQFVANNPGQVCPAKWKEGAKTLAPSLDLVGKI
The following text describes a protein:
Function:
Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress (By similarity). NPW23 activates GPR7 and GPR8 more efficiently than NPW30.
Subcellular Localization:
Secreted.
Sequence:
MAWRPGERGAPASRPRLALLLLLLLLPLPSGAWYKHVASPRYHTVGRAAGLLMGLRRSPYLWRRALRAAAGPLARDTLSPEPAAREAPLLLPSWVQELWETRRRSSQAGIPVRAPRSPRAPEPALEPESLDFSGAGQRLRRDVSRPAVDPAANRLGLPCLAPGPF
The following text describes a protein:
Function:
Low-affinity nitrate transporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVHVSSSHGAKDGSEEAYDYRGNPPDKSKTGGWLGAGLILGSELSERICVMGISMNLVTYLVGDLHISSAKSATIVTNFMGTLNLLGLLGGFLADAKLGRYKMVAISASVTALGVLLLTVATTISSMRPPICDDFRRLHHQCIEANGHQLALLYVALYTIALGGGGIKSNVSGFGSDQFDTSDPKEEKQMIFFFNRFYFSISVGSLFAVIALVYVQDNVGRGWGYGISAATMVVAAIVLLCGTKRYRFKKPKGSPFTTIWRVGFLAWKKRKESYPAHPSLLNGYDNTTVPHTEMLKCLDKAAISKNESSPSSKDFEEKDPWIVSTVTQVEEVKLVMKLVPIWATNILFWTIYSQMTTFTVEQATFMDRKLGSFTVPAGSYSAFLILTILLFTSLNERVFVPLTRRLTKKPQGITSLQRIGVGLVFSMAAMAVAAVIENARREAAVNNDKKISAFWLVPQYFLVGAGEAFAYVGQLEFFIREAPERMKSMSTGLFLSTISMGFFVSSLLVSLVDRVTDKSWLRSNLNKARLNYFYWLLVVLGALNFLIFIVFAMKHQYKADVITVVVTDDDSVEKEVTKKESSEFELKDIP
The following text describes a protein:
Function:
Involved in development during embryogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MPRPCRESYGDQKPPYSYIALTAMAILSSSERMLPLADIYRYIMERFPYYRKNTQRWQNSLRHNLSFNDCFLKVPRRPDRPGKGAYWTLHPNAINMFENGSLLRRRKRFKLHKADKDLLETELAA
The following text describes a protein:
Function:
Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity.
Subcellular Localization:
Mitochondrion.
Domain:
RAP domain is required for FASTKD3 function in mRNA stability and translation.
Sequence:
MAFITLRRAFCHKSILWIPGAVVALKIHPASHAPKAVTDRLSVCFCSLQPELFRVRFHHAYCKNFHSEKGNDFHPVGEPWSSQAQEWNQPGQSLQNEDEEMLFRRLSYFTSFEEVLSFISALDTLPVPLAMAALLRICEIGRRDGEQRLPEGVLENRAFQALCLRCERDPSHLTNAGLVTALQSLLTLLPADPQSSLMLSLVAECQRRLQRGNLEVHHLCVLGESLAMLQGASCETLKLVVRQLQSKSVETFAPEEITSVYRILQVCPEEVDKHQMFLNTLNNFSISVVPYLSPKSISHVLTALVALDQTHALPLLIKLGKYVVRYIPRFTNEELRKVLEAFVYFGHSDRFFTEALEQHVSALCFSLDPAVASSVMGYCSRKRILSKPIFDVVSEIVVCQWDRLSPSQIAELIEPFGKLNYVPPNAPALFRKVENVLCARLHHFPPKMLLRLLHSCALIERHPVNFMSKLFSPFFLQRLQGKESYLDRLSLAQLTQLFLTSVLECPFYKGPKLLPKYQVKSFLTPCCSLETPLDLHLYKSVVIGLIDLLGSRLYFASKVLTPYYYTIDVEVKLDEDGFVLPCTVDEDIHKRVALCIDGPQRFCLDSKHLLGKEATKQRHLRLLGYQVVQLPYHELELLTSRLELVDYLQRKLFSQSSAVHW
The following text describes a protein:
Function:
Controls stomatal patterning.
Subcellular Localization:
Secreted.
Sequence:
MALPISLSTSLKLALTLAAFFSFLPPTSVGLVLSRSGRSELGKAENDEMKNLEEKMVIGSRPPGCQNKCMNCRPCMAAAVVPVHRMKGKAFQSFSSSREEEDSYYLLSWKCRCGNKIYQP
The following text describes a protein:
Function:
May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons.
Subcellular Localization:
Nucleus.
Sequence:
MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHQESRLNSVSSTQGDMMQKMPGESLSRAGAKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHPVHPILGGALSSGNASSPLSAASLPAIGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCPCTICQMPPPPHLSALSTANMARLSAESKDLLK