lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. Also, involved in the degradation of oxidized and glycated proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MDFPSVERAVKVYRECASAPSLSSASLQKTGDSVFSVHSTWSQRDLERECNIKYRQTHIVTLDSNGQIGDVIDPGTNTELNSEQLVRWSPSGKLKAVLRKIKDKKGDEKQYLEVWNNIAKIHNINLTALDKHGKVYEDGEFGCLEWSSCESQLLYVAEKKQPKAVSYFDKSKEGGSEENPETDAKKKDPEVKGDQFVHRQDWGELLVGKHSPVPCILNLQTGQVTIPEGLPNDVSVGQAIWTPDDSGIVFTGWENEPYRLGLIYCRNRRSAIYHLDLSSQTCNTISITGQSVRSPVFSPDASKLIYIQNSCHGPHMQCAQLIVYHWESKETKVTVDIVQRPTEGRPFPGLYVGRFEQQCWLDNETILVSTAWRSSQTIIAINICTGEVTRLTNGPDFGSWMFCDIKQRLILACRSSPTRSAQLVVGVIPQEGDISCINWKPLHESSVILSDVIWSVITLKPKTEQGSDIDFETIILKPKANSGSQEKKLPLIVWAHGGPHSVFSTGYLLLPGLFCQLGFVIACVNYRGSIGFGQASIDSLPGFVGTHDVKDVQAAAEAVIEQGLVDRERVAVSGGSHGGFLSTHMIGQYPDFYKACITRNPVTNLAAMLGGTDIPSWTMTEAGMDFDFKIAPSAEMYAKMFNCSPMAHIDKVRAPTLLMLGSDDLRVPPQQGIRYHEMLKARGVKTRLLMYPDNSHPINKVDAEADCFMNMYTWITEHL
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MEEEKQQPSVVVLPWMRHPVDITRYQELPICSVPLMKRRSHSETVGPGDFERDLCIKLPIESGKTLAYAFPIVQNLSTDTGGRLRALVVVPTRDLSLQVKRVFDALASLLGLRICLATDQSSLRHKLSSLIYLPGEDDGQDPGFLSSLWFQSKVDILVVTPGRLVDHVNKLSLKHLRYLMVDEADRLLREDYQSWLPTVLKLTQSRLTKIVLSATLTRDPGRLAQLNLHHPLFLSTGKMRYRLPEYLECYKLICERKVKPLYLVALLKSLGEENCIVFTRSVESTHHLCKLLNCFGDLKIGIKEFSSLKHQRT
The following text describes a protein:
Function:
Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation.
Subcellular Localization:
Cytoplasm. Midbody. Nucleus.
Sequence:
MELEEQSSKVVPTERCHAPTAGDFCVSEVPELLRAIWEEPERPWRNLGGRVKTHRQHRHRLCPLGRENYALRKLREAANGNDLDTVQQLLDEGADPCAADDKGRTAIHFASCNGNDQIVRLLLDHGADPNQRDGLGNTPLHLAACTSHVPVITMLLRGGARVDALDRAGRTPLHLAKSKLNILQDGKSQTLESLRLEVKQIIQMLREYLDKLGQQEQTEQLDQICSRLQRTSTKEQVDEVTEMLASFTSLSLQIQKMENR
The following text describes a protein:
Function:
Required for cell division.
Miscellaneous:
MISCELLANEOUS: Present with 2140 molecules/cell in log phase SD medium.
Sequence:
MTGGQSCSSNMIVWIPDEKEVFVKGELMSTDINKNKFTGQEEQIGIVHPLDSTEVSNLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAPVSGSSIVESFEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDRAEQASFKNDVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNLDHGSATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRLKNGFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPEGEKSSSAGVEANISNQEVKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRKEITYHLQKLKKTRVIGNTFRLYNRLVKEDPWFNLFIRIKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGLQETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFNDKLSSSEEDLDIKLVTLEKNCNIAMSRLQSLVTENSDLRSKNENFKKEKAALNNQLKNKESELLKMKEKIDNHKKELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETKEQEQKKRNSLVESLNDSKIKELEARLSQEISLNQYLNKRISGNSVETNISSTRRSTSYSDDPLDKEDIIKKYYDLQLAFTEITRNLENEIEEKKNLISRLRFTETRLASSSFEDQKIKAQMKKLKKLIQDMDPSIPLDSILNEPLDNCPDKESDINKLMLEVDYLKRQLDIETRAHYDAENAISALHSKFRKIQGESSLSSSDIYKLKFEASEERVKSLEDKLKTMPLRDRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKLSQLTLDLRQSKSKEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQGNELRLREHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWEREMERNDSDMQLQETLLELKRVQDVKKILSDDLAHLKERLSAVEDRSQYTDEINRLKEELNCSLKAETNLKKEFATLKYKLETSTNDSEAKISDLLKQLDHYTKVVEMLNNEKDAISLAEKELYQKYEALNTECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEITEKIKYLEETLQLQMEQNSRNGELVKTLQASCNGYKDKFDDEKQKNIDLYEENQTLQKLNTDLQLQLKNLHERLSDTTEKNAWLSKIHELENMVSLETDLKYEEMKKNKSLERAVEELQTKNSQQTDVIELANKNRSEFEEATLKYEAQISDLEKYISQQELEMKKSIRDNSSYRDKVQEMAQEIEFWKSRYESTMIGSKNIDSNNAQSKIFS
The following text describes a protein:
Function:
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
Subcellular Localization:
Cytoplasm.
Sequence:
MANENPEVVVAPVVENGGAHGGRQLFDRETEQLESELSKKLEITEDANNENEEDVAAEEEEGSKGETSTKKTKKKKSKSKKKPQQTDPPTIPVVKLFPSGEFPEGEIQQYKGDNLWRSTSEEKRELERLEKPIYNSVRQAAEVHRQVRKYVRSITLEDTVRKLISENGLKAGIAFPTGCSLNWVAAHWTPNSGDKTALQYDDVMKLDFGTHIDGHIVDCAFTVAFNPMYDPLLAASREATYTDVRLCDIGAAIQEVMKSYEVEINGKVFPVKSIRNLNGHSIGPYQIHAGKSVPIVKGGEQTKMEEEKGYVREDLECSHYMKNFDVGHVPLRLPRAKQLLVTINNNFSTLAFCRRYLDRIGETKYLMALKYLCDAGIVQPYPPLCDVKGSYVSQYEHTILLRPTCKEVVSKGDDY
The following text describes a protein:
Function:
Subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane. This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox.
Subcellular Localization:
Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSLPQQLRDESDFDQLPDNIPVTATIADIEEKKGFIVYFSFVIEVKTKGNSKYLIYRRYREFFALHQSLELKYTAEAQSGYYNCQLPTLPGKVFMGNKKEIAESRIPELNNYMKRLLCLPTWVLLDDLIRMFFYQTESDSQQVPRALRRLRPPTRKVKTVKPKTDLLSAPRAEAVFDFSGSGRLELSLKAGDVIFLLRRVNADWLEGTVRDRTGIFPESFVKIIKALPENESDEEGGASRNSSRAQGSYSCLHCYFLQPEGIETRDICVQEDLSIQPSYEELLSRMRDVFHVDDIALNYRDAEGDLIRILDDEDVVLMVQESKRTESKVKRPVNQFPWELLVTHAKDLTVYNTEY
The following text describes a protein:
Function:
Plays an essential role for maintaining proper localization of the seven-protein complex and the viroplasm during assembly.
Subcellular Localization:
Virion. Host cytoplasm. Note=Localizes in viroplasm and in the mature virion (MV).
Sequence:
MDFIRRKYLIYTVENNIDFLKDDTLSKVNNFTLNHVLALKYLVSNFPQHVITKDVLANTNFFVFIHMVRCCKVYEAVLRHAFDAPTLYVKALTKNYLSFSNTIQSYKETVHKLTQDEKFLEVAKYMDELGELIGVNYDLVLNPLFHGGEPIKDMEIIFLKLFKKTDFKVVKKLSVIRLLIWAYLSKKDTGIEFADNDRQDIYTLFQQTGRIVHSNLTETFRDYIFPGDKTSYWVWLNESIANDADIVLNRHAITMYDKILSYIYSEIKQGRVNKNMLKLVYIFEPEKDIRELLLEIIYDIPGDILSIIDAKNDDWKKYFISFYKANFINGNTFISDRTFNEDLFRVVVQIDPEYFDNERIMSLFSTSAADIKRFDELDINNSYISNIIYEVNDITLDTMDDMKKCQIFNEDTSYYVKEYNTYLFLHESDPMVIENGILKKLSSIKSKSRRLNLFSKNILKYYLDGQLARLGLVLDDYKGDLLVKMINHLKSVEDVSAFVRFSTDKNPSILPSLIKTILASYNISIIVLFQRFLRDNLYHVEEFLDKSIHLTKTDKKYILQLIRHGRS
The following text describes a protein:
Function:
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
Subcellular Localization:
Nucleus.
Sequence:
MPVNLNNLLNSTPVSPPHSHFHPSKNQGPSAIELSNLLSPAVDTHRSLPNQQQQQHYYDYDNQPEEEEEEEEEEEDEEQKQFLEALQAPPPLTQPSTHTLPAPIFNRTRAPNQSKLTSYQRPIPFTSFSYDEHRLIRTGNSQFDSLRPFHVPHDFLGFDLAHRFDQAVLRDESIDEGIDGLLVSLIDFLDKADPKERLDICRGVLSAGLITWRGVLTKLCSTVYETGGEGERGGWTKEVMMVDGTVYVIDGPKTASEDGGSSAHQTYYGHSYESLVTNPDGFQDVNTNTQWVAVVKANLNGNRIILGGEVDCIDPLVFNQVHQQLSNPHPHHQSPPPIPIDHFVEIKTSVIPSSERDHWNLYRFKMLKFWLQSYLLGVPKIHVGLRDRSGIVRDAQDYPTHEIPVLVKQPQTKPGGRWSSELCLEGGGGIISFVVDRLRRDGAEGGQSRQRLFQARLETIIAQEAARWRAEGAPAQPGLSDSCFRQIASLAQWPVYSLRFRPAQNQGVPGTLELVESPAELVAQSVAHRMSDHLFGFLHPLSNPPHDHRQSFKPSRIGFLPSLWINYLVLTRVQLALESDPSSASRNFKHHSST
The following text describes a protein:
Function:
Chromatin-binding protein that acts as an adapter between distinct nucleosome components (H3K36me3 or H2A.Z) and chromatin-modifying complexes, contributing to the regulation of the levels of histone acetylation at actively transcribed genes. Competes with CHD4 and MBD3 for interaction with MTA1 to form a NuRD subcomplex, preventing the formation of full NuRD complex (containing CHD4 and MBD3), leading to recruitment of HDACs to gene promoters resulting in turn in the deacetylation of nearby H3K27 and H2A.Z (By similarity). Plays a role in facilitating transcriptional elongation through regulation of histone acetylation. Negatively regulates brown adipocyte thermogenesis by interacting with and stabilizing HDAC1 at the UCP1 gene promoter, thereby promoting histone deacetylation at the promoter leading to the repression of UCP1 expression.
Subcellular Localization:
Nucleus.
Sequence:
MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLSPSTLLPLADNSSAVSCHGQAPEEGTGEVMQLETGPLHPHHKDPEKDQPPKTAVSEPPPPLIPPVPAGNLPPFPPYFEGAPFPHPLWLRNTYQQWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTVSPQEASPSPLNTPKPRRRLGSGPDSEHRKPEEPEDSAVIATAAPRRSKREKREEDRVAGERVPRSPVIKISYSTPQGKGEVVKIPSRVHGSVEPFCPQQSLQNGSQDSEVSRDVEPRGGGDRPPSGSSASIPKLKLTRPVPPISDLPPPKIRLKPHRLGDGEHEPLYRAELVEELNGCPRGPLVSSPALFADGSSHGLEDLSSGSSGEDDDLKRFPQGKHGRDGLAFLVDCPGRRTDCTSESVCSTDSLDELKSSGSEVTSPDTGDLSSGDSASVPSSSADTRQTVPPLTVRLHTQSVSRCVTEDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDGEPSWQEAKVSWFGSPTTSFLSISKLSPFSEFFKLRFNRKKKGMYRKAITEAANATQHVAPEIRELLTQFEM
The following text describes a protein:
Function:
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation.
Subcellular Localization:
Nucleus.
Sequence:
PRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKAEKVPKGKKGKADAGKEGNSPAESGDAKTDQAQKAEGAGEAK
The following text describes a protein:
Function:
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
Sequence:
MAWQRLLQSPRQISSGRYIHQLSRYYCSSYQQIPLSQPLPNIATPKYAPTIENSTQNPQLTQLSNGIKVITAPCYGQVGYIGAIVDAGSRYELAFPKGISHLMGKICFQGSRKFENKEDFIDKLDSYGVNVQCEMNRDCAVYSISGFRHGIPDMFAALADSILFPDLSQRNVENQKAALNAELEHIKMMADAEIILTELIHGAAYGEKSVGFSKFADMETFPEIDTSSLQRYHELLYTPKRLVIGGVGVNHQELVELAEKYFVSDVPSWFKSSTSPVEDETEYIGSNMDLPKAPAGPTMTAAMVSELSHAAFALQGVSYMDPDFFSLAVLSLLMGGGGSFSAGGPGKGMYSRIYRSVLCNYYWMFSCLCLQHCYVDSGLFVINASAPPEQMGQLAEVVMTTICNMKNGFHKDEVSRAKRQLQSVLLMNLESKQIMLEDLCRQTLSLPAYTSVQELCDNIEQVTEESLIRVVDRILSSKLSVAAYGNLKHFPSHEQMQEAMTNNGRIKSQSRFSFYS
The following text describes a protein:
Function:
Acts as a transcriptional repressor. A histone deacetylase (HDAC) activity is required for transcription repression. May play a role in telomere stability.
Subcellular Localization:
Nucleus.
Sequence:
MKRIRDDVYASGSQFRRPLGSSRGQLCGQSPVHGSGDTEEEEEGGSRRVSQKLTTNDALSYLREVKEMFQDQREKYDRFLEVMKDFKAQRTDTGGVIARVKELFKGHNNLIYGFNTFLPKGYEITLIEEDDALPKKTVEFEQAINFVNKIKMRFKHDEHVYKSFLEILNMYRKENKEIKEVYNEVSILFQGHLDLLEQFTRFLPASLPSHSAAQHSRSQAQQYSDRGSDPPLLHQMQVEKERRRERAVALRGDYSVERYDLNDDKTMVKIQREQRKRLDKENRARRGRDLDDREAGQDNLHHFPEKRKSSRRAEALEAYSGSASHSEKDNLKSMYKQAFVFCEKVKDRLCSQDDYQTFLKCLNIFSNGIIQRKDLQNLVSDLLGKFPDLMDEFNQFFERCESITDGFQRLAGVMSKKLFSSEEQLSRPMKVEEKESEHKPELEAVKETEQCKKEYMGKSIQELDLSDCECCTPSYRLLPADYPIPIASQRSELGAEVLNDHWVSVTSGSEDYSFKHMRRNQYEESLFRCEDDRFELDMLLESVSSAARSAESLLNIITEKKISFSGSFRIEDHFTALNLRCIERLYGDHGLDVIDILNKNPATALPVILTRLKQKQGEWKKCRDDFDKVWANVYAKNHYKSLDHRSFYFKQQDSKNLSAKSLLAEIKELKEKSQNDDDVLLSISAGYRQPINPNLEYEYLNRAIHEDMFKVVQFSCEELCSTKEQLSKVLRLWENFLEAVLGVPPRAKGTDLVEDVVINPKTLDVNHSTSPNGEAAVSSGGDTARLASRKLKSAANGDENSSSGTFKHGIGLLNKDSTGKENLEDVEIANRDGVACSAVKPQKEQETGNEAEKRFGKPIPMDISERAAISSISIPSGAENNHCVVGKEVLPGAHEIQAKPSDTLTDIHHDVDSIETVHSTQGGDVGNSIVLANGLRSDSSKGTRNSDDPEGPSRNEKEEGELSPNGDFEDNFGVYKDHGVKSTSKPENSAEAEVEADAEVENEDDADDVDSENASEASGTESGGDVCSQDEDREEENGEHDEIDGKAESEGEAEGMDPHLLEGESELLPQSERVLLSVRPLSKHVAAVLCDERTKDLQVFYGNDDFYVLFRLHQILYERILYAKRNCSGGELKSKNLKDTNAGDPYARFMRVLYGLLDGSAENTKFEDECRAIIGNQSYVLFTLDKLIYRLVKQLQAIVADEMDNKLLQLYEYEKSRKPGRVIDSVYYENVRVLVHEENIYRLECSSLPSRLSIQLMDNIIEKPEAYAVSMDPTFASYMQTELLSVSSGKKEEGHDIVLQRNLTGLYDLCKAMEGVEVVNGLECKMSCSSYKIAYVLDTEDYFHRKKKKKKTEQLWQRNKVRVERFHRFLSA
The following text describes a protein:
Function:
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular Localization:
Membrane; Single-pass membrane protein. Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MSGSTGERSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFSVINFRQPSNA
The following text describes a protein:
Function:
Involved in photosystem II (PSII) assembly and/or repair. Probably involved in conversion of late PSII assembly intermediates into mature dimeric PSII, it may mediate the optimal equlibrium of HliA/HliB among the intermediates containing CP47 (psbB) to facilitate photoprotection during assembly (Probable).
Subcellular Localization:
Cellular thylakoid membrane; Single-pass membrane protein.
Sequence:
MNNYTKDDDGRLNNFAVEPKIYAADAPSKADKRNYLIMAAITVVLVAGLIAVAVVASGAST
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Sequence:
MKLTVVSAVILVVVFVAWPVSAGGSGHEEEEDDTKSWFPLDNLLSLNYYDKSCPNFEKIVDTKVRQWTKSDPSLGPALLRLLFHDCGVTGVQRPNGRDVKSAVAGARSRDGGHLSRGPPDHEARYPLRHLPTRRHFSLTDSTSSTLSSFPGPTPSEKHTVEPSNRGFTTSTQHMELIRPLILNSQIT
The following text describes a protein:
Function:
Functions as an E3 ubiquitin ligase.
Sequence:
MPLLDNPVVSDVSPSELLNNSFEELSQYVDELREQFESWQPLSSRILYVLRIESLASKMRESSLEVFQLLKHLPADLVSPSEDCIELVKLVGREEVSYTIDLALIDQRKGVELTPEVLVKIAESVGLRSNQDILIEGVVLTNLKEDANLVKDNTRAGFIKGLIYLTKQMHDYLAKIEQSQSPSDFFCPLSLQLMTDPVTVTSGQTYERAFIEKWFDMGLMVCPKTRHALSQTTLTPNFTVKAFIANWCESNNVNPPDPLELIHSNQPFPLLVGSCSADDSRDSLPLPVMDDTLKCNHIESVDASKCEELHQVLTRSASAPGIVSKVVSKANTSISQAPGETVPQPWIIPATMKETGSSSNMEAEETGGSSSMEVEVKKLIQDLKSSSLDAQREATAQLRLLTKDIPDDRTVIARCGAIAALVNKLYSMDKMIQAEAVTCLLNLSLDDSNKTVIAYSGVFKPLVHVLKTGNMEAKENSTRALVSLSKAEENRTKMLQAGAIEPLVRLMGNGSPRGKKDAATALTNLATRNREKEMVIRGGGVRYLIQMMNPAAGTVERAVVVLANLANVPEAKIAIRDGGGIPLLVDVVELGSPRGQENAAAALCVLCMDSSRFCNIVIREGAIPPLVALTRSGTTRAKEKAKSLLKYFEALKQENQRRN
The following text describes a protein:
Function:
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTVPRTGRPGGIRAAAPSRSGWRTQAPVVAVVALGGGTGAAARYAASLWWPTPAGGFPWTTFGVNAVGCAVIGVFMVVITEVRPAHRLVRPFFGTGVLGGFTTFSTYAVDSRSLFADGRLPTGLAYLAATPLAALTAVWLAAWAARRVLKWRQS
The following text describes a protein:
Function:
Probably involved in the repair of mismatches in DNA.
Subcellular Localization:
Nucleus.
Sequence:
MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFGILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMNLNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAWNLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEEKDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTESLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
The following text describes a protein:
Function:
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKKKTQNQAAKRLINHYSAWKYVVLVTTIIILTLSAIPTWYGEQPSIQLQSKDATSVLRNVPELTQLLNKQNIQADEITQQGDNTTLVFANETQQSQARNALDALVKEGDTITYSYVSVAPKWLGNLGFSPIKLGLDLRGGVQFLLNVDVDKAFQEQRDSMMDAVKDSLRAERLRGVVVQAMGNDAFEVKTEQPQALSHVRKYLQENYRGWEIRQGSDQLQVQPSQQNKSEFQTATIQQNLKIMRDRIEELGITEALVQRQGEHAIRIELPGVQDPSQAKNVIGATASLAFYEAKSPTDARSYDDLILEDGNGRPVILAKRPVLSGEHIVNARAGVDNMGMSEVNISLDHAGGKIMSDFSGKHIGKPMATVYREYKTNARGETVRSEKVISVATIQSQLGSQFRITGAGSMEEAQQLALLLRAGSLTAPVTIVEERTIGASLGEENIANGFAALALGMAMTLTFMALWYRRLGWVANVALLVNMACLLGLIALLPGAVLTLPGIAGLVLTVGMAVDTNVLIFERIRDKLSEGRNFAQAIDTGFDSAFSTILDANITTMITAVILYSIGNGPIQGFALTLGLGLLTSMFSGVFASRALINLVWGRDTRRDVRV
The following text describes a protein:
Function:
Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein.
Sequence:
MVQNMEINVSFLTDSEQEFILEVLRRDEDLRHLEDLRVKKLKAEFLDIRRKGAKRGSGKYSERSCGRCQEPLSLLSGSGSQCRSCKHQVCKKCQSVRPNGSWVCTVCAKEIDLKMSTGDWFFDERVNRFSSAPGHDLVRVSLRKRPLSKKHETAGEILLNKVELNPSQAAPVPKPRLKDIALANKSSLLEDEEGQQSDTESIEKASLDSDHAETKFSHSTPQMQRKEELRANSPEDCAVSILMSTVNSDSTATIETASLIHHMNACSDSLRDVDGLFKKSVRRVHKLSEIKPASTLDLREDASENTTPSMGDRSKSVPGLNADDEEEEEDIDNLVNIHRQKFGSSMGSLGGSRTTLGSMMSVYSEAGDYDHVEVSGEIVFSLSYDEPSQSLSVMVHECKGLAYADPAKKKCNPYVKAYLLPDKSKKKTSIKHNNINPSFKETLKYSISRTQLMTRTLQLSVWHYDRFGHNAFLGEVEVLMDSYDIDSAHEECMALRGKAVPQSLLSPFDQYKGELVISLKYVTPNAPNAEDSKGKGKKSKPADGSELHVLIKEAKNLTALKAGGTCDSFVKGYLLPSKSKSSSKKKTPVVKKTKSPNYNHTFVYNNLSLDELKDMCLELTVWDRETLSSNDFLGGVRLSLGAVTVKEGKEEWMADSTGEEILLWKKMMQYPDSWAEGTLPLRSSMGKGK
The following text describes a protein:
Function:
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSWQAYVDNQIRAQVSCKVAAIAGLTDGAIWAKHEEPNVTITQQELKTIADAIRTNPTVFNVSGVHLGGEKYICLTAEPCLVRARRGSSAMIAVATNTCDEVMVSLYGVPPGTLNTVVEKLGDYLRSNNY
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MEREPKVARDFFGLNPVVKDEAKEREDFYKGFTVNDFGQFNTSVKDSASMANGMQWPFSINASALQQFMSFKGAQEDRHKKVVFDQLASSGFQPISTAGAYETNHRAPTATQKGFTLETNGAPITKSHSQYGMSCMPYPSQAAIEQGSISHHSQGIGTLPLSSHSIPISMSSPFFKMHGGAGNPSSVKSFGGIPVTSQHPVTSSVGTLAGSFLPRSVPCTLAKPASSAAQLTIFYAGSVNVYDDIPLEKAQAIMFLAANGANQSVKTPNSRTQVPSLPIATVEGIPSNSAMPTCSGLSSPMSATSQLQAAAHSSSDLVAVKTISSLAPSNHQEPPKQTPAALNARAAVPQARKASLARFLEKRKERVSNMGPYTTKKSPEHSSTVESGASDSPDCVGICSKVDHKWSLGPPLNSEVGNARS
The following text describes a protein:
Function:
Promotes efficient arsenite-induced clearance of stress granules (SGs). May have a role in the ubiquitin-proteasome system (UPS) protecting cells from metalloid-induced proteotoxicity.
Miscellaneous:
MISCELLANEOUS: Present with 4280 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSAAIEKETGMLDVGKHCAYCRQLDFLPFHCSFCNEDFCSNHRLKEDHHCRWLLEHEEVHKTEKSPSKSRDGSSSNDEAYFKSLLPERASVRIQRVSETREPLRGSNTAKVSSTLNSKTLDKIFKFFQRNEKRKSNNKSKKNFGSSSNKIIQLANLKKIAKGDPKIPMQNRIYIWCYLVDGDETDIAKEDTRMPLYINKMWPVGRAMDYLSIQLNVKSSTLTNSSSNDKFQLCKLKEGKQVSFYNIGASLRVTNEIKDLDTLYLVHNNADEKSN
The following text describes a protein:
Function:
Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.
Sequence:
MKTEFSLAQLADPDIAEADKILRACVHCGFCTATCPTYVLLGDELDSPRGRIYLIKEMLEKDQTPTAEVVKHVDRCLSCLACMTTCPSGVNYMHLVDQARVRIEQRYQRPLTERLLRQVLAFVLPDPQRFRASMWLARLARPLAVFLPTPRPSATPGLVQRLKAMLALAPNRLPSPGPLPGSVFAALGKKRGRVALLQGCAQQVLAPRINQSAISLLTRHGIEVVLVRDEQCCGALTHHLGNDHDALARARANIAAWRAEAAGEGLDAILVTASGCGTVIKDYGYLLREDAAFAADAAKVSALAKDITEYVAGLDLATTAIGDNIVVAYHSACSLQHGQKITGLPKELLSKNGFVVKDVPESHLCCGSAGTYNILQPELAGRLRDRKVANIASVKPDMIAAGNIGCMVQIASGTSVPVVHTIELLDWATGGARPALNASS
The following text describes a protein:
Function:
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).
Subcellular Localization:
Nucleus.
Sequence:
MSKNGTTGNKKKKTKLSTAATIAANIAKANATLNNNNNSNNNSNNTNIGNSINGIPSSLPPSVTLPVEELISFAPECLLFSQLLEFEEKLDASINKRLIDIQEASRRNSIKNIRTLRLSIYNTYSNQSAYYHLDNKSLNSVQERPSWSLRVEGKLLDESQDELVNKSIKSSSSSSSTANKRKFSSFFKKVFIQIGHRDTCEWDKSQTFTETDGFEIKRNGNQEVDIKILMYLDHVPQKYKVLGGLSQLLNIHTDTKPRIILALWHYIKSNTLLDAETKKITCDENLKNIFSLEELQFNQIPQLLREHLSPPDPLEFQYTLHLSGDAKDYEQAYDIQVEVDEPIFNPNPTMRKEISQLNDEINHHIQKVYQHKRKREFMEKLSSDPLGFLNDTTANLVKDFQVSKSTTSTGFEEERHASFYYQPMTEELVKNYLSKQTTPNPTPQQISMAPSTPQTP
The following text describes a protein:
Function:
Zinc metalloprotease that mediates intramembrane proteolysis of proteins such as ATF6, ATF6B, SREBF1/SREBP1 and SREBF2/SREBP2. Catalyzes the second step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2: cleaves SREBPs within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Mature N-terminal SREBP fragments shuttle to the nucleus and activate gene transcription. Also mediates the second step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B). Involved in intramembrane proteolysis during bone formation. In astrocytes and osteoblasts, upon DNA damage and ER stress, mediates the second step of the regulated intramembrane proteolytic activation of the transcription factor CREB3L1, leading to the inhibition of cell-cycle progression.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MDPFVFFIVLASLYGVLYFFDRFFKSCMHYPYDAFLKNTGLSINFMSLHWHTSAFNRTLLRWGSAGNSCTRRVMITSFNVGVLVTFSLLPIGLILLIATIFSSGEQDSSSSVSSPVGVPVQLEILLPGVNLPLEEIGYYITTLVLCLVVHEMGHALAAVMEDVPVTGFGIKFIFCLPLAYTELSHDHLNSLRWFRKLRVLCAGIWHNFVFAGVCYLLISTVGITMSPLYAYNQHVVVTELTRKSPLRGERGLQVDNQITQVNGCPVNSEESWVTCLQNSLKLKPGYCVSADFVQLNDESSAISHHSIDGQLQCCDELNPNVSCFEVVEDANGDVPVELPQHVCLNVRRTLEEVSEHCSSGVCNEGFCLRPLIRNITAIMTFKRQNFRGEKLPPVIYVGHPWDVTRTVEVSAFVPRYSLLKAAWPDAWLLLLKYNVVFSIGLALINAIPCFGFDGAHITSTVIHSFLVGRVDQHAKRDIISLIITSVGSLLFALALLKVAWLSFLRPLL
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MASRFFAGGSSTESDSESSDDGILVPQKQAPLTRFFLSDDEEETKRVVRSAKSKRHDEISEFIKQIKNQKKIRDVSRVLTSFEEMMKVYTKAQNVLNTDDGQCPRFYIRCLVELEEFVNELWEDKKKLNKANAKSLSSLRQKLRKYMKELDAQITKYKDNPDAEDKEEEEREVEKKEEESDSEEDEPKSAPVLKKVAPPKVKQEGDYDDESDDSWDASMSEDSSSDDDVPGMTTLTAEYFLKKTTTGDDRASKKKERRKDRVRPKDEEALEEEEENEDGEGKWEKVKGGIKLEKEKPKMFAKDVEITPTVVLKKLGEIVGARGKRATNRADQIELLKELRNIASQHNLGLGVDLKVAFHVMSAVFDYNPNVATCMKPAIWEMCLALMQEMLDILMANPDVFVSENLNEDAESLSEPPYKVRGCILTVAERLDEEFTKMLQATDAHSTEYVERLKDETIVTGLIVQLQSHLENTSTSSEICRVYLRNIQHIYYKYDYEKLRELEKSRAKTEEESQEKTDESKEKTDEIQEKTEGEGQEKTDESQEKTKGESQEKTDESEGEKKKEEEKPTEEVKLEEGEEEKEKGKGEEDSLTLMDRMCKYIYSKDTTDLIRTRTMLCHIYHYAIHDRWYTARDLMLMSHLQQTIQFSDIPTQILYNRTMVQLGLCAFRHGNIRDAHNALLDIQSGGRAKELLAQGLLMRQQERDAQQEKIEKSRQLPFHMHINLELLECVYLVSAMLLEIPYMASHHFDIRRRMISKSFHHQLRLSERQTLIGPPESMREHVVAASRAMRYGDWRGCKKFLINEKMNMKVWNLFKDSDHVRKLITRKIQEESLRTYLFTYGSVYDALSLITLSDMFELEKTAVHSIVSKMIINEELMASWDEPAATIVMHRCEPTRLQHLSLRLADKVSNLVENNERLIDARMGDSRFKGRDFNKDGNRREGGYKDGGRGGYRGGGRDNRYHGDNQGGNRYRDGGGRRGGYNRDGGGGGRRGGYNRDGGGRDNYNRDGQSGGYRGGYRGGYNRGGGYQDRGGRGRNRDQGRNY