lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Functions in cell migration.
Subcellular Localization:
Recycling endosome. Membrane; Single-pass membrane protein.
Sequence:
MEKARRGGDGVPRGPVLHIVVVGFHHKKGCQVEFSYPPLIPGDGHDSHTLPEEWKYLPFLALPDGAHNYQEDTVFFHLPPRNGNGATVFGISCYRQIEAKALKVRQADITRETVQKSVCVLSKLPLYGLLQAKLQLITHAYFEEKDFSQISILKELYEHMNSSLGGASLEGSQVYLGLSPRDLVLHFRHKVLILFKLILLEKKVLFYISPVNKLVGALMTVLSLFPGMIEHGLSDCSQYRPRKSMSEDGGLQESNPCADDFVSASTADVSHTNLGTIRKVMAGNHGEDAAMKTEEPLFQVEDSSKGQEPNDTNQYLKPPSRPSPDSSESDWETLDPSVLEDPNLKEREQLGSDQTNLFPKDSVPSESLPITVQPQANTGQVVLIPGLISGLEEDQYGMPLAIFTKGYLCLPYMALQQHHLLSDVTVRGFVAGATNILFRQQKHLSDAIVEVEEALIQIHDPELRKLLNPTTADLRFADYLVRHVTENRDDVFLDGTGWEGGDEWIRAQFAVYIHALLAATLQLDNEKILSDYGTTFVTAWKNTHNYRVWNSNKHPALAEINPNHPFQGQYSVSDMKLRFSHSVQNSERGKKIGNVMVTTSRNVVQTGKAVGQSVGGAFSSAKTAMSSWLSTFTTSTSQSLTEPPDEKP
The following text describes a protein:
Function:
Required to regulate responses to abiotic stress (drought) and to oxidative stress leading to cell death. Confers sensitivity to paraquat (PQ), to the catalase inhibitor aminotriazole (AT), and to the fungal Alternaria alternata f.sp. lycopersici toxin (AAL toxin).
Subcellular Localization:
Nucleus.
Sequence:
MVRSNKQEPRVSSTYIRSLVKQQLAYSTTMTTTTTTTTNDGSGGGKTQTQTHKKQVRRRLHTSRPYQERLLNMAEARREIVTALKQHRASMRQATRIPPPQPPPPPQPLNLFSPPPPPPPPDPFSWTNPSLNFLLPNQPLGLNLNFQDFNDFIQTSSTTSSSSSSSTSSSSSSIFPTNPHIYSSPSPPPTFTTATSDSAPQLPSSSNGENNVVTSAWWSELMLKTVEPEIKPETEEVIVVEDDVFPKFSDVMEFPSWLNQTEEELFHPYNLTDHYSSSPHNPPLSCMEIGEIEGMDGDDWLA
The following text describes a protein:
Function:
Plays a role in the inhibition of host cell division. Interacts with and inhibits the major host cytoskeletal protein in bacterial division FtsZ to confer growth advantage to the phage.
Sequence:
MSTTNVQYGLTAQTVLFYSDMVRCGFNWSLAMAQLKELYENNKAIALESAE
The following text describes a protein:
Function:
Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
Subcellular Localization:
Nucleus.
Sequence:
MYYDPLVALVNILPVEKLSDENSKKKSRWERNATNNIIENKVVVSNKWGSEDYKPYLPLPFVDFPPGLTPAQLDQFLREQRYDELTKKLNKGELEYVDPDIRPPSPPPIYDKNGSRINTREARIKNSMIEEHHRLIEYLLKHVDGFVAPPTYKPIKKIRKIEIPIDKYPEYNFMGLIIGPRGCNHKRLEAESGAQISIRGKGTLKEGKKTDHQTEIEAAMPKHVHIAADTEECVEKAVSLITPLLDPFHPLHEEYKRKGLEQLALVNGINLNQLDTQKCSICNSNTHLTFECPENMNIQNFKKPEIKCNLCGDHGHITLDCKLAKQSSNYINKNDLENSNNLSQPIHTHVHSPAPPPPPPPPPLYDPLISTPQGFNGMYKMDTKKMDLEYEKMMNELNSDPNKEKKNDDIYKKLSENTMDNIGNTNDIMNMNNDKYNISNDSNMIQTNNNNNINDNKELYKNENEYNLNYIETNNNYMNNYSTNINKYNPSSHHNINNPNFIPLPQNNNENHFNNMLNFNNVNNIPLTPPLPILPNFLNIPFIDNDLMANPAFAYQAKAPLSLDPIYMQNYASWAQIPMNYAEQLLVNAPAPDTNPPPLPSDSVCLNKEENTNTT
The following text describes a protein:
Function:
Catalyzes the conversion of farnesoate to juvenile hormone III acid in juvenile hormone biosynthesis.
Miscellaneous:
MISCELLANEOUS: The enzyme is specifically found in lepidoptera (moths and butterflies) and is specific for farnesoate. Other insects contain the methyl farnesoate epoxidase, which is specific for methyl farnesoate.
Sequence:
MLALIVLCFILFFYIISRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIREVSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGDECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKELCSLVMRLFKLVDMSGGFLNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQENLQLGAPKDVIDAFLIDMLESQDDKPTLDDLQVVCLDLLEAGMETVTNTAVFMLLHVVRNEDVQRKLHQEIDDIIGRDRNPLLDDRIRMVYTEAVILETLRISTVASMGIPHMALNDAKLGNYIIPKGTFILLSLYELHHGPHWKDPETFRPERFLTKEGNILQDEWLIPFGIGKRRCIGEGLARSELFMFLTHILQKFHLRIPKNEPLPSTEPIDGLSLSAKQFRIIFEPRKTFKSI
The following text describes a protein:
Function:
Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity.
Sequence:
MWARDAGGVPVGTNLYGTHPVYYEHRAGSGLSHGVLLLNSNGMDIKINNDNGQYLEYNVIGGVIDLYFMAGPAPFDVAREYSEITQKAAMMPYWGLGFHQCRFGYESADQVAEVVANYSKANIPLETMWTDIDYMDGYKVFTLGQSFPLDKMRALISDLHSKDQHYIVMVDPAVAAQNYDAYNNGVNADIFLKKNRTMSPRQSRDISRASSHGIVKEKNGRRTASYPVGRGSMKDAAVDLTNDRENSKREASASGNKKGLPNRNLLDPSYKINNAFRVLSNKTADTDIIHQNGLAEYDTHNLMLNRRPDKRPMVITRSTFVGAGAHVGHWLGDNLSAWDQYLISIRHLLQFVSIFQVPMAGADVCGFLQNTNEHLCARWTVLGAFYPFYRNHNVNNAIPQEAYRWTSVAEAARKAIDIRYRLLDYIYTAMHKQTVDGTPMLAPLWMQYPTDSKTFAIDTQFFYGPSMLINPVTDEKSTSVSFYVPQGVWYDIRDQKPITGTGSTITYNNLSTSDIAILVKGGSIIPARVNSAMTTKALRDNDFELLVAPDADDKASGTLYLDDGESLVQDGTSEIAFTYGGGKIKMAGSFGFSTKVGVKSFTVYGDAPQKYELNEGLDAPWEHDVASLKKL
The following text describes a protein:
Function:
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MSRQLFAICLIAAVCASGVYGSCKATVSSFSTQDATILTQLAHVGEFTLQCSGAAPASLFAEFPCGKVVPVAKVGDNKYQVSWVEDIKQGSSGNVQVRLFDEDGYANVRKAQRDGDKVSSVKSLLDISVPTKGAYKGPWIKAELLAAFLVGGFAYFAFTTKGKVQS
The following text describes a protein:
Function:
Mediates homophilic cell-cell adhesion.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MQQSGVPGSRGCALCPLLGVLFFQGVYVIFSLEIKADAHVRGYVGENIKLRCTFKSSSSITDKLTIDWTYRPPSSSRTESIFHYQSFQYPTTAGTFRDRISWVGDVYKGDASISISNPTMKDNGTFSCAVKNPPDVHHNIPATELTVTERGFGTMLSSVALLSILVFIPSTVVVILLLVRMGRKSAGLKKRSKSGYKKSSIEVSDDTDQEGDDCMAKLCVRCAECVDSDYEETY
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
Subcellular Localization:
Nucleus.
Sequence:
MDGGGEGQMDQSTDHTADDSGTLSMAVHLEGTPQGADGTQGLLTNDYSYVLDDSATGASANDSIASGGDDDGGHKDGDSLREHVGVEPLQEQDRFLPIHNISRIMRKAIPKKEKIAKDAKECVQECVSEFISFITSEASDRCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKYRESMKGEKGGMNTSTTGAGDESLASDLGADDSFTANIISTDGQTTMTYTYPTQVQVGMIPVLDMGQQLQFTGMSS
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MVAIVGENMAKKRSRTTCSPDFKLLSQMIFIIPKKLKAGNGVDLETANGRHNFKNKKFSDPATVTKWKDERMKAFYTEETPFQVLHGHTGDVLDLAWSDSNLLLSASKDKTVRLWRVGCDECLHIFHNNNYRGGGNYMINRSMTFTGQVRALEKIFELGNKLEPERKMQLGKALGLQPRQIANWFQNRKSRLKTKQLERDYDTLKKQLDVLKSDNDSLLAHNKKLHDGFHRCQSSNLGVVGTDGAARNIFFVGSIAFQDVAHKVSALKVFLNRGDMARLKEIQEAVLQMSAPKALRNELIHKLRSERMSYHGDESSWNRSWLWASKWNVRAYVSRKLELTHDAACMSVLVQESCGDYAFVIHTNNPVTGDPSKIHTRDCEGFGRDLGWRISRTSNELYHQENKPQLANREKQKTDSVCMLTPVSI
The following text describes a protein:
Function:
Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.
Sequence:
MARLKVLNVAEKPSVASSIAEILSKGRPNKIKSCSKYNPVFTFDYKIKNDIWYMYVTSVTGHLTDQKFDDRYKNWHNTDPQELFDAEITVYVEKDKKNIENNLKKYSKECNMLILWLDCDREGEHICFEVINACRITNRKLIIHRAQFSAVTEKDIIHAINNLKEPNKNLAYSVDVRREIDLRMGSIFTRFMTIRYIELVKHETSIISYGPCQFPTLGFVVNRYLDIKNFKNEYYWSIKMKYVYNNDEINPMDDENNYDDHDDEQMDSDSDESDSYYTNNDDSNNYSDETDDYYGDEKKKKKKKKTKKKKKKKNSTKKKKKKKKNKINNNNKKNKHNNVVDFTWSRIRLFDHLAVILIYEELLKNPLCKITNVYESETRKYKPYPLNTLQMTKLVSIYFKISSKECMMLAEKLYNKGYISYPRTETNYFPDSMNLHKIINELRKNDNFGWYANKLCEEHKYQKPRKGKMNDKAHPPIHPVKNMNKSLKVEEKEWKLYEFICKHFLAVCSNDAIGYNTKVTAKIQEEQFFCKGLKIKEKNYLEIYTYEKWNDKIIPSFQVDDEFYPTSLLIEEGITQPPKYLSESNLLTLMDKFSIGTDATMHEHIENIQKRNYVIKNSKSLFIPTNLGIALVQSYKKFKDIGIDLTDPSLRAKMEKDMSLVASGVKQKNEIIRNYIDIMKYIYQEIYNRIDVLDKNIHYYLNNPDQLSYT
The following text describes a protein:
Function:
Antimicrobial peptide that probably forms pores in target membranes. Has antibacterial activity against Gram-positive bacteria S.aureus NBRC 13276 (MIC=5-10 uM) and B.subtilis NBRC 3009 (MIC=2.5-5 uM) but not against Gram-negative bacterium E.coli NBRC 3972.
Miscellaneous:
MISCELLANEOUS: Fragments comprising residues 4-17 and 5-17 have been detected in venom but it is unclear whether they have a physiological role or are simply due to degradation.
Subcellular Localization:
Secreted. Target cell membrane.
Domain:
Amphipathic and cationic peptide with an alpha-helical structure.
Sequence:
MKFQYLLAIFMIVLVVTDHCQAFIGMIPGLIGGLISAIKGRRRRQLEARYEPQQRNFRKREIDFEKLFANMPDY
The following text describes a protein:
Function:
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1 (By similarity). Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSDAFSTPADHALSHPELEAILENAQAGPSSIGDGAEGMSIEEAFEVDETVRRVLEGDYKTIGLQFPDELLPSSVSVYRAIQTRIAHTGAQAYVLADSTYGNCCPDVLSCLHLPADFLVHYGHACLTPTDALPVHYVFPRQKLDVKQAVESLLAASKNELDGDGRKGIVVVWDVSYDWLANDIRDTFSQDSTIQISFASIQKPTLASQKGLKDVKGKTPALRSVEPPQGLEMNDCVLWYIGEEGRSCMNLQMTHANNPLFIYSPSSQSVSPLHRTTSRLLSRRLFALHQALSADVFGLIVSNIGLASSKPLLAQLREDLKRAKKKSYTLSVGRLNPAKLANFAEIECFVLVGCAEGGVVDSKDFLRPIITPWELELALQGPDHVWAPENWTLDLGTVLKDAQEREIKIKQDSSTADSDDDSLEFSLITGTMRTKKRFAFGNGTHTLENNKLLGDGGVQDLTLRNQNFSLSKLESAGSTFLASREFQGLEPRYGMDEPSVLEQGRSGVARGYTEEK
The following text describes a protein:
Function:
Required for the processing of the 27S pre-rRNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKRKLPVNESSSDSDESDVDSDEELLEAYQRGEVQPGLNQKEEVARTFTNNTTLLKSKLSDLHLKLDWVERLDLTTSLEPIVDSILNGKEDTEPQYKIETPGDRIVDDLQRETLFYRQAQSAIIEGLARLKTLGIPTKRPEDYFAQMAKSDDHMLKVKRRVLTQQMAQEKCQKVKKLRELKKYGKKVQIEVGLQRAKEKKELLSKVKQYREGKLASLDFLDDDGGKKKNMVEITKQKTKERNESKVFQPMSKGPVKGKGKGKGAVKGRGGKGDKRASKENKFGFGGKKSGSKKNNMKKDSGNDRNSKAGRGGPGGRAKQGGGKKAKGGGGARKR
The following text describes a protein:
Function:
In vitro, has activity towards 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), 2,6-dimethoxy-phenol, and guaiacol. Although brown rot fungi preferentially degrade hemicellulose and cellulose, the enzyme may contribute to generating small amounts of lignin breakdown products required for catalytic reactions.
Subcellular Localization:
Secreted.
Sequence:
MLLSSAFVGSCLAILNFAAAVSAQGGLSRTTLNIVNKVISPDGYSRDSVLANGIHPGPLISGNKGDTFQINVNNQLHDNSMNTSTTVHWHGIDQHHTNWADGPAFVTQCPIVPEHSFLYNFTVPDQAGTFWYHSHESVQYCDGLRGPLVVYDPEDPHKDLYDVDDDTTIISLSDWYHSPAHELLPGPIPPNSTLINSLGRPDGSDLPVTIIEVDPTKRYRFRLISMACHPYFDFSIDGHNMTIIEADGSNTEPLSDIDQIRIYPAQRYSFVLEPNQTPGDYWIRAAPLQLGNTSNPDTTTSLGLAILRYTNRSGYAQAASVDPYDISQTPIPVNPLLEQNLHAYGDVPELDEECDDCKLTFDFAFNFTAVDFTVNGTSYVNPTVPVLLQILNGTYTAQELLPHHSVYTLPRNKTIEITMPGAVTGGPHPMHLHGHSFYVIQSMGSDTTNTVNPVLRDTVAVGGATGDNVVIRFRTDNPGPWIMHCHIDFHLALGFAVVLAEAPQDVAEYVSPIPTWDELCPIWDNAPSHN
The following text describes a protein:
Function:
Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Associates with enzymatically active telomerase. Plays a genomewide role in DNA replication and facilitates re-replication at non-telomeric loci.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MDRSLQSTHAKLVARDIQRLTQSPTESNSFSLLGGACVSRVEIVGTIVSRDLTPKFLKFGVDDGTGCVTCVMWLNQLTSSYFSRWDPATILLLASAARKQAAQIRIGAVARVRGRVGSYRGVMQITANVAVAERDPNAEILHWLECLKLGQSCYRVRIQS
The following text describes a protein:
Function:
RNA helicase.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MAKRVAMSKAQKEAQAKRAKKSDNSRPSSLSHASLQKTERKTVDPTKLAWSTVHLPSEAQSGGAGVTESDFFNSLDWNDDDFMGLQEIDDVEVLQESRGDGSRTITFLASETKLKNKQDNAAIASSAQKAPVKTAEAKLKANKKRPKKRTIDEVAPNVEIDAAPAPMESQELTAVTKDSDEPDSDGYETAADVTLLPQEDTADSDLDLDDNDLAEAFRNAHQLDLQDDEADEAEFDDKLLPAWSHLALHSDLKRALLHKGFKQPTEIQRKAIPFALGLQQEATSSDDSEDTADSAAIGAPSTRRKRDVVGVSQTGSGKTLAYGLPILNYLFENAENAIASSCRRNAVDDLPPPLGALILCPTRELALQVSSHLIDLVRASCIVSDIDVDQPEISHRKLLRRPQIAVVCGGMSEQKQRRLLEGRSRQGDRKAGVDIIVATPGRLWEMTRLDDHLAARIKQTRFLVLDEADRMVEVGHFAEMEHILNLVNRSEAKRPSEGQDGQQHVSGSDKEDESEVEIPTHGVKPSSSMQTFIFSATLSKALQVNLKRRRKLKQFAKKRHSKRKENATTLDELMDRIDFRDQAPAVIDLTPAQGLPQGLMETKIECVGKDKDLYLYYFLLRYPGRTLVFVNSIDGIRRLTPLLTQLNVMCYPIHSQLQQKQRLKNLDRFRAFERCGQASNCVLLATDVAARGLDIPSVEHVVHYQLPRSADTYVHRSGRTARAGSSGVSLALIEAKEKQLWTQLCRAMSRQSDISSLPITFSTLSLLRERVELALAIDKQTHEANKQQHDDNWLAKLAEDADLVMSDDDNVDPDAPTSKRGGSSASKAAEAKLNEMKNKLSALLSRPITMKGLSHRYLTAGGLQGSAWVDDMVRQQNHRQILGVQNTDAETDLKSSQTSQPVKKKIKSDNAGKASAAATAGAPAKPPKPASAVSASTEKRKRKKKPRSQLKRKPYQL
The following text describes a protein:
Function:
Required for DNA damage induced mutagenesis. Involved in DNA repair, mitochondrial DNA repair and translesion synthesis. Has a role in the bypass of abasic (AP) sites (By similarity).
Subcellular Localization:
Mitochondrion. Nucleus.
Sequence:
MENDTGWSVKKCIDIFGEFLLVSIHCILYARRLYPQDLFIKARKYNTIVWQSRHPILCEYIEEVVQSCIEELQTGSVHQVALSIINKEQREEERYVFSTDSIPIIPDFLLEKQISTNEPFTDAYVEYMRASLIQLLNITNGLPLIEQECTWTLRVTLKDGFPRPKQWEEWFLPPQARETDATRQFKGITIPVRNVDIGPMMTEIWVEKYTNSD
The following text describes a protein:
Function:
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
Sequence:
MHKKVLLAILDGYGISNAIYGNAVQNANTPMLDELINSYPCVLLDASGEAVGLPMGQIGNSEVGHLNIGAGRVVYTGLSLINQHIKDRSFFANKAFLKTIEHVEKNHSKIHLIGLFSNGGVHSHNEHLLALIELFSKHAKVVLHLFGDGRDVAPCSLKQDLEKLMIFLKNYPNVVIGTIGGRYYGMDRDQRWDREMIAYKALLGVSKNKFNDPIGYIETQYQNQITDEFIYPAINANLNSDQFALNNNDGVIFFNFRPDRARQMSHLIFNSNYYNYQPELKRKENLFFVTMMNYEGIVPSEFAFPPQTIKNSLGEVIANNNLKQLRIAETEKYAHVTFFFDGGFEVNLSNETKTLIPSLKVATYDLAPEMSCKAITDALLEKLNNFDFTVLNFANPDMVGHTGNYQACIKALEALDVQIKRIVDFCKANQITMFLTADHGNAEVMIDNNNNPVTKHTINPVPFVCTDKNVNFNQTGILANIAPTILEYLNLSKPKEMTAKSLLKNNN
The following text describes a protein:
Function:
Acts as a transcriptional repressor. Prevents the photoperiodic and circadian clock-dependent transition to flowering in long days (LD) by repressing the expression of flowering time genes (e.g. FT, GI and CO) in the leaf vasculature, and by interfering with floral meristem identity genes at the apex (e.g. SOC1 and LFY).
Subcellular Localization:
Nucleus.
Domain:
Contains a slightly degenerated ERF-associated amphiphilic repression (EAR) motif, which may be involved in the activity of transcriptional repression.
Sequence:
MEDHYHQVEVEGEEEIKPSKEANKTDENTSSLRIFPCLFCSRKFHSSQALGGHQNAHKKERTAARRAKRAYDFVNNNDFLHTLPVFLSSPSQHHLTILGYPASASVACFPTVHPDHPIFKSSGSHVVLATSHQGRDCKGGYCCQQRVDILDHHYNVVNSDKGKDQCLDLSLHL
The following text describes a protein:
Function:
Functions as an E3 ubiquitin ligase.
Sequence:
MELTSVRCLINSISRFIHLVTCLTSKSMPGQKNYKNIATLLKLLKPVLDDVAQQKAPSDETICRQCEELDVAINEARESLEEWSLKKSKILWVLQSEPELLKIQSIALKLSHTLCELLESSPPSLGPSEIQPFIQEIQKFEVGQISKQMNMAPEVGKILVSESLTEMIHSLNFVSHEELLNECIALEKERMNAKDNETRGDLDKISLSIDLFSDIRDCMLELDHFKAIDGIKIPPYFRCPLSLELMVNPVIIASGQTYEKTSIQKWLDHGLTTCPRTNQALAHSNLIPNYTVKALIENWCEVNKVRLNGNPESTHDGITSNPVHLTDMDDVRGSSDTSNSMSRLCHQGGQAFEKVDCTSELSEEEFSACRIREAEKSGHTSPGISYIHSRSESVSSAVSSIEYLPSASTDVSRISSKHDNVSDTSGEVQCDYRISSPCNKSVGNSPNLSARQYHSSKTMSEMAVNGLHNHARQLSLPTKSASDDLTTSSHVEKLIRDLESQSTEVQMAAAAEFRFLAKHNMENRAIIGRCGAIAPLISLLNSDVKPTQEHAVTALLNLSINEDIKAMIAEQGALEPLIHVLRTGNAGAKENAAAALFSLSLLEEYRKKIGRSGAVKALVDLLGLGTIRGKKDAATALFNLSIFHENKARIIQVGAVKHLIRLLDPSNVMVDKAVALLANLSTISEGCLAIAREEGIPSLVEIVETGSQRGKENAASILLQLCLNSPKYCRLVLQEGAVPPLVALSQSGSPRAKEKAQQLLSHFRSQREGATGRGKS
The following text describes a protein:
Function:
Part of the signal that specifies dorsal cell fates in the embryo. Acts together with dpp.
Subcellular Localization:
Secreted.
Sequence:
MLNVFFLTSLFYAASATTYVTTNNHIEMPIYQKRPLSEQMEMIDILDLGDRPRRQAEPNLHNSASKFLLEVYNEISEDQEPKEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRANFTVSVYRKLDNRQDFSYRILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRISIGDSQLSTFAAGLVTPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHLPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGCH
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD7 to trigger SMAD7-mediated transforming growth factor beta/TGF-beta receptor ubiquitin-dependent degradation, thereby down-regulating TGF-beta signaling. In addition, interaction with SMAD7 activates autocatalytic degradation, which is prevented by interaction with AIMP1. Also forms a stable complex with TGF-beta receptor-mediated phosphorylated SMAD1, SMAD2 and SMAD3, and targets SMAD1 and SMAD2 for ubiquitination and proteasome-mediated degradation. SMAD2 may recruit substrates, such as SNON, for ubiquitin-dependent degradation. Negatively regulates TGFB1-induced epithelial-mesenchymal transition and myofibroblast differentiation.
Subcellular Localization:
Cell membrane. Cytoplasm. Membrane raft. Nucleus.
Sequence:
MGLGRDTRAPCVPRGVRPSSGALGAGDLAHNPAPETALPTTNPALQQAPPPSPPRPQEPTSGGGGGGGGGGSGPRTGFPQTRGRAEEEAAEHPPASADFAPSAPRPRGTEKGRPRRAARTGGGGGARRRRRGRPRLPLCCAARAEEAEVGGGGSSASRSLRGSWRRRSAHPGPSGPGGRGAGCSDPGPGRCGDSSAPRRRPSPAQPARPRAASAAAAAASPAAGDMSNPGGRRNGPVKLRLTGLPDPFAKVVVDGSGQCHSTDTVKNTLDPKWNQHYDLYIGKSDSVTISVWNHKKIHKKQGAGFLGCVRLLSNAINRLKDTGYQRLDLCKLGPNDNDTVRGQIVVSLQSRDRIGTGGQVVDCSRLFDNDLPDGWEERRTASGRIQYLNHITRTTQWERPTRPASEYSSPGRPLSCFVDENTPITGTNGATCGQSSDPRLAERRVRSQRHRNYMSRTHLHTPPDLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLSNINCEELGPLPPGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLNRQNQLKDQQQQQVVSLCPDDTECLTVPRYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVSDWKANTRLKHCTPDSNVVKWFWKAVELFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCGFAVE
The following text describes a protein:
Function:
During embryonic development, interferes with neural crest formation (By similarity). Inhibits AP2 transcriptional activity by interaction with its activation domain (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MPHRKERPSGSSLHAHGSTGTAEGGSMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRGFSVAASCGGGVDSSQFSEYVLCREERRPQPTPTAVRIKQEPLD
The following text describes a protein:
Function:
Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Recruited to specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease, via its interaction with SHE3.
Miscellaneous:
MISCELLANEOUS: Present with 2210 molecules/cell in log phase SD medium.
Subcellular Localization:
Bud. Note=Accumulates preferentially in growing buds.
Sequence:
MSFEVGTKCWYPHKEQGWIGGEVTKNDFFEGTFHLELKLEDGETVSIETNSFENDDDHPTLPVLRNPPILESTDDLTTLSYLNEPAVLHAIKKRYMNGQIYTYSGIVLIAANPFDKVDHLYSREMIQNYSSKRKDELEPHLFAIAEEAYRFMVHEKANQTVVVSGESGAGKTVSAKYIMRYFASVQESNNREGEVEMSQIESQILATNPIMEAFGNAKTTRNDNSSRFGKYLQILFDENTTIRGSKIRTYLLEKSRLVYQPETERNYHIFYQILEGLPEPVKQELHLSSPKDYHYTNQGGQPNIAGIDEAREYKITTDALSLVGINHETQLGIFKILAGLLHIGNIEMKMTRNDASLSSEEQNLQIACELLGIDPFNFAKWIVKKQIVTRSEKIVTNLNYNQALIARDSVAKFIYSTLFDWLVDNINKTLYDPELDQQDHVFSFIGILDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFSDNQPCIDLIENKLGILSLLDEESRLPSGSDESWASKLYSAFNKPPSNEVFSKPRFGQTKFIVSHYAVDVEYEVEGFIEKNRDSVSLGHLDVFKATTNPIFKQILDNRELRSDDAPEEQNTEKKIMIPARLSQKKPTLGSMFKKSLGELMAIINSTNVHYIRCIKPNSEKKPWEFDNLMVLSQLRACGVLETIRISCAGFPSRWTFDEFVQRYFLLTDYSLWSGILYNPDLPKEAIVNFCQSILDATISDSAKYQIGNTKIFFKAGMLAFLEKLRTNKMNEICIIIQKKIRARYYRLQYLQTMESIKKCQSQIRSLLVRTRVDHELKTRAAILLQTNIRALWKREYYRAAIGQIIKLQCTCKRKLILDSVNRKFMLMAAVIIQSYIRSYGHKTDYRTLKRSSILVQSAMRMQLARRRYIVLQKEVEERNIRASYGIGLLEEAIEFKNSFILNLEMLNDSYTRLTQLLQGDLSNIPSKQRQEYETIVNGYNDKISKLKTLQVEIMNTLNKKNALKERKKKQSSLIQSHMQSLAAIKGNKPSRLSDEVKSMKQELAFIENVIAQDFTTTYSANKNDKVKGLGIAGQQVKPKLVNVIRRESGNPDLLELLMDLNCYTLEVTEGYLKKVNVTEVNGDNVLGPIHVITTVVSSLVRNGLLIQSSKFISKVLLTVESIVMSLPKDETMLGGIFWLSNLSRLPAFAANQKTLYEANGGDEKDKLTLIYLNDLENETLKVFDKIYSTWLVKFMKHASAHIEIFDMVLNEKLFKNSGDEKFAKLFTFLNEFDAVLCKFQVVDSMHTKIFNDTLKYLNVMLFNDLITKCPALNWKYGYEVDRNIERLVSWFEPRIEDVRPNLIQIIQAVKILQLKISNLNEFKLLFDFWYALNPAQIQAILLKYKPANKGEAGVPNEILNYLANVIKRENLSLPGKMEIMLSAQFDSAKNHLRYDTSAITQNSNTEGLATVSKIIKLDRK
The following text describes a protein:
Function:
Glycerophosphodiester phosphodiesterase hydrolyzes glycerophosphodiesters into glycerol-3-phosphate (G3P) and the corresponding alcohol.
Miscellaneous:
MISCELLANEOUS: There are 2 isozymes of glycerophosphoryl diester phosphodiesterase in E.coli: a periplasmic isozyme (GlpQ) and a cytosolic isozyme (UgpQ).
Subcellular Localization:
Cytoplasm.
Sequence:
MSNWPYPRIVAHRGGGKLAPENTLASIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKMFKGEPLPLLSQVAERCREHGMMANIEIKPTTGTGPLTGKMVALAARELWAGMTPPLLSSFEIDALEAAQQAAPELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLNKARVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVIGPNFTAQ
The following text describes a protein:
Function:
May play a role in responses to biotic and abiotic stresses.
Miscellaneous:
MISCELLANEOUS: [Isoform 3]: May be due to a competing donor splice site.
Sequence:
MDEEARAAGCSPAPPRAPAASCGAAAELCLCSPTGVEGIEQVPGCPCFEDAGAVVVSGEAPEGPGVLCSEDGAELKLAEQGALDVRLGSPAVGIHEQQLLHRGTSGSDEAGAINEISPVEVSPSEASSNLDTAGAIGGSPLMLESLPETSDTRGCEQEVMPGVVVGSSNRDASSEVGVESERGSDADGRNGLGEGELVSSVDGGGAEKSSKVTGVLSEEGVDGMETALEPCVASVGSITQVEEGVDRMETSLDDSEASDGSTTQDFDTDVETESSGSSIEEQDMGYGVHIPHTEQAICEVARGNKSSEVKSSDRMSSVTLPTLILASGAAMLPHPSKVLTGGEDAYFIACDGWFGVADGVGQWSFEGINAGLYARELMDGCKKAVMESQGAPEMRTEEVLAKAADEARSPGSSTVLVAHFDGQVLHACNIGDSGFLVIRNGEIYQKSKPMTYGFNFPLQIEKGDDPFKLVQKYTIDLQEGDAIVTATDGLFDNVYEEEIAAVISKSLEAGLKPSEIAEFLVARAKEVGRSATCRSPFSDAALAVGYLGYSGGKLDDVTVVVSVVRKSEV
The following text describes a protein:
Function:
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSNKEIRIGERDDATSSSTSGDRLGVLHLEKNEQTTKKLKRKLRKTEKTNLTRGRLSQEDKKAFKFADIVPMNSDWQKYFRERLSNHFASSKIEKTILKADYHGALLTVWMAENSTQIGISGIVVLETRHTFQMVTQDDRFVVIPKKGSVFRFILGDRLFSLFGDGMRTRPAWRGKKPRVKRVIPTFIRGTLHTVPTASE
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Sequence:
MTTNKPSFSYFKVLVLGQLPRFTLNYFGTDFTDNYVESIDDEFRKTLKFGQLPLFVDSDGFRLTQTDAICKYIAAKHDFLGKSIKERAIVDETIAAVHDDVIIPGYKVGKGVEDKKVIDTIISRHFTTFENVLAENKFIAGGDNYTLADLYVFVAYHYYKHLGHSEKFQNKFPHLEALQAHFESNKGIAEYIKNRPDSGRGI
The following text describes a protein:
Function:
Is involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MTASRTIVRVLGGKLSLSIARARLALELRSVAYELMDEPLEPRKSDRLLTANPAYGKIPVLLLLDGFAICESVVIVQYVEDVAQAGGGAGGEGEAAALLLPEDPYERAMHRFWTAYIDDRLWLAIDAVSLGPTSETHVQATGDARAALRLLEGAFTDCSSGVGFFSGSDVGLRAPPRALPIDASTTPLMDRWSHRFAAHPAARRGLPDTNKVVEFTRFFQAKFKVDVSK