lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Brevianamide F prenyltransferase; part of the gene cluster that mediates the biosynthesis of fumitremorgins, indole alkaloids that carry not only intriguing chemical structures, but also interesting biological and pharmacological activities. The biosynthesis of fumitremorgin-type alkaloids begins by condensation of the two amino acids L-tryptophan and L-proline to brevianamide F, catalyzed by the non-ribosomal peptide synthetase ftmA. Brevianamide F is then prenylated by the prenyltransferase ftmPT1/ftmB in the presence of dimethylallyl diphosphate, resulting in the formation of tryprostatin B. The three cytochrome P450 monooxygenases, ftmP450-1/ftmC, ftmP450-2/ftmE and ftmP450-3/FtmG, are responsible for the conversion of tryprostatin B to 6-hydroxytryprostatin B, tryprostatin A to fumitremorgin C and fumitremorgin C to 12,13-dihydroxyfumitremorgin C, respectively. The putative methyltransferase ftmMT/ftmD is expected for the conversion of 6-hydroxytryprostatin B to tryprostatin A (Probable). FtmPT2/FtmH catalyzes the prenylation of 12,13-dihydroxyfumitre-morgin C in the presence of dimethylallyl diphosphate, resulting in the formation of fumitremorgin B. Fumitremorgin B is further converted to verruculogen by ftmOx1/ftmF via the insertion of an endoperoxide bond between the two prenyl moieties. In some fungal species, verruculogen is further converted to fumitremorgin A, but the enzymes involved in this step have not been identified yet (Probable).
Sequence:
MPPAPPDQKPCHQLQPAPYRALSESILFGSVDEERWWHSTAPILSRLLISSNYDVDVQYKYLSLYRHLVLPALGPYPQRDPETGIIATQWRSGMVLTGLPIEFSNNVARALIRIGVDPVTADSGTAQDPFNTTRPKVYLETAARLLPGVDLTRFYEFETELVITKAEEAVLQANPDLFRSPWKSQILTAMDLQKSGTVLVKAYFYPQPKSAVTGRSTEDLLVNAIRKVDREGRFETQLANLQRYIERRRRGLHVPGVTADKPPATAADKAFDACSFFPHFLSTDLVEPGKSRVKFYASERHVNLQMVEDIWTFGGLRRDPDALRGLELLRHFWADIQMREGYYTMPRGFCELGKSSAGFEAPMMFHFHLDGSQSPFPDPQMYVCVFGMNSRKLVEGLTTFYRRVGWEEMASHYQGNFLANYPDEDFEKAAHLCAYVSFAYKNGGAYVTLYNHSFNPVGDVSFPN
The following text describes a protein:
Function:
Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.
Sequence:
MEKPLAGKNILVVEDEVVFRTVLAEYLGSLGATIHQAENGLAALYQLKGHSPDLILCDLAMPKMGGIEFVEQLLLKGIKIPVLVISATDKMADIAQVLRLGVKDVLLKPIVDLNRLREAVLACLYPTLFTSHAIEETELIQDWEALRKNPSGALQLLKQLQPPAQQTLAHCRINYRQLTMVEKPGLVLDIAALSDKDLAFYCLDVTRAGDNGVLAALLLRVLFNGILQEHLTHQQQRLPQMSSLLKQVNLLLRRTHLDGQFPLLVGYYHVEYQNLILVSAGLHANISAGKNQIQLNNGVPLGTLKTAHLNQVSQRCEAWQCQVWGGGSRLRLMLAAEE
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Sequence:
MHVVVRTGPFKGNISGCNPKTVCDDENFGGPSWGSFLGRKDGLTASQTGANKALPSAFDPLIAIASKFAAVGLDSRDLVALCPFIWPRSLFLTPRLYDFNKTRKPDPTLSRTQLKILQKSCPRGGNRTALTNLDPTTVNTFDNRYFSNLQASAGLLQSDQELFSTPKSNTVEMVNQFSANQTAFFESFVASMIKMISYISVLTGMEGEVRTRCRRVNNI
The following text describes a protein:
Function:
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MAQAKKGDKQKGLGGVPITYIAGALLAAAAAAFFALRGRAHFTKGPILTPLKAPKVTDLLEFDAAYKDRMLWGSYRSGLYFGMRTRTPKGLVSGLMWFDPDDFQTLQQYRVRHEASQGDGLASYGWKRHDGRTYGQQVLVDNDYNITLSMLKSFGEGSGPGGDWSVRLQLRRTSGMPTQRRRISVVIYMGDEDTPREPWQVLPDGEVTDLRPQPAALLTGGSAALGRGGARWALHAMEQATEPPASRRSRGCRVDYLGMSTEGHKPDYLLKVRELLLSTMYERLQRQPPSDKFRLYLPNGATTNSDLALFQVTCVIPSTVDFAFTSSSGDVSDSSERLEGLLGPGLDGPLAAAEAAFDQRFDRVFGEGIARALQPQQQPDSAASPDASTPDAPDAAAVVETAKAALSNLLGSMGYFYGSSLVRTGPPGSEPAPYWPAPLFTAVPSRSFFPRGFLWDEGFHQLLLQRWEPALSRDVIAHWLDLMNAQGWIPREQILGEEARARVPPEFVVQLPWHANPPSLFLPIAHMAAQLGRAQQQATDGTAAASDAESAAELERVRAFLRRAWPRLAAWYNWFNTTQAGPLPSSFRWHGRDPLAASELNPKTLTSGLDDYPRASHPDDSERHLDLRCWMALAAQAMADIGTSLGLPAAAVARYAAAAEQLSDLRQLAALHLDQGRGVFADWGTHTEEVALEVKSIVVPGGEGQPPQRRDVSERVTTGWPQPQFVPQFGYVSLFPLIMRLLPTGREPNATASAAATAATAGATAAAGGAALTLQQLQLLTDPSLLWSEHGLRSLAKTASLYKKRNTADDPPYWRGQIWINVNYLVLRSLSYYARHGSPEVAAAAAAAHDELRRRLLRTLVGGYKRQGYLYEQYDDESGRGTSSHPFTGWTALVTLIAAQEY
The following text describes a protein:
Function:
Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEGVVTAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADVSAQLLERLWLRWNPAYHLKEATV
The following text describes a protein:
Function:
A positive regulator of the alternate pathway (AP) of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b).
Subcellular Localization:
Secreted.
Domain:
TSP type-1 domain 0 binds to TSP type-1 domain 4, and TSP type-1 domain 1 binds to TSP type-1 domain 6. These interactions mediate multimerization.
Sequence:
MITEGAQAPRLLLPPLLLLLTLPATGSDPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRSPRWSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPACKDPEEEEL
The following text describes a protein:
Function:
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
Subcellular Localization:
Golgi apparatus, trans-Golgi network.
Sequence:
MSTAPGILDLTSPQFDVDAYVSKLLKEKSLDALVAEEENMVNCVRRLDSDVHQIVYENYNKFLTATSSVRKIEKEFKHLDSEMQSLGDSMSSISRLVKELSPVIDGKKGQASTLARSYRTVHAVQFVSELPATLQSLLDDHDYSSLIRLALKARSSLFPYSDVPNVISVLEKVTTIVDAAEKELRALVGASASSVEAAGEAISLLSQLGVPEEQLRDSLIQAAEATLRRDLSTLSSSPADVLELVDEACSSFLPDLALCASLYRSHFPSTKEEMLSRLRPLLDQLNERIRQALLTVVPHDTALTVRSLDRYYSKCAALSQHLPELDNVSACSSLVNEISTREVKLCRERIRNELASAISSIRESLLVDSRSSLPPLIASLMGAALLQMKTALAHLLLFTASDVAFSSTAQSSSSFRAPFARLVYQEVLVGANKDACSLSLSTCSSHASSQPSLALILALAAHEWTAKYAQLEVLCREQFSIGGDDAREMSKEDEISSLWRSAAHQMLTQYVQQTAVTLGDPWCNALSVVNTPTQPRGVSLATKRLREEMGQLADTVASVFGEEIRKETRQSRGMGRAVTMPSEGLKDSLWSERVDLHAIVHFKKTSMLVAIAKGVLKSGVEGVRMNTLGSHAMQQIQVDVAYLQDSFSHLIGEDALLTSLFDAILSSSLRRCGNPQLLHPNVVSSLMAEDDIDK
The following text describes a protein:
Function:
Metalloprotease.
Sequence:
MTLWRFVCVIVAMTTTICGRCHAQDPDDDTMGAFERILKVNKEADSLSPPVGQTPFEGDIAITPRQQQAIQAQLQNQRAGDVAANAVAALATLRWPKGVIPYTIDCSLGTGPCRRPPTRTGRAAVPPTIAGLSMRWPKGIIPYTIDCSLQNIPAALTAIKTAIRQWEERTCIRFVKRTTEKDYLDFYRNKYCQCPVGRIGGKQRLSVGNGCEYTHVMIHEIGHAIGFWHEQSRPDRDNWVEVLWDNIEPGLDTAFDKYGKAEIDSLGVEYDYGSIMHYPFNAFPRSPGLETLRALQEVTQQPYRQLSEKDVLQVQLMYDYCRDRSDSDLPPGADDPVCDDLDASCKDWAEAGECENNVNWMLYHCKDSCNTCDGPCEDSEARCPQWAREGECVDNAEYMLLNCRKSCRSCRVSGQHAHAPPMAAGLMMRPVGPETVPEEALPPEVQSGILARGETDENNVAELLGNPIAEREKKWLRAYLVIRNACIRSRNQLGAFRRQSLRHCVRRCNDDVRCASFDYIPSYRSCYLSLDNRESAPHDFDGCTEEYRRITNYYEKKKTRERSSESDVPDGYGVIRNTCIKGRNQLGNFYGETLDQCASRCSADVRCKSFDFVAMYQSCHLSVDDRVSAGEDALCTEQYSAITNYYEKIPDEAPSIGDFLRINEGCILGRNQLGSFYDETVEQCKGRCGNDYSCRSFDYVHTYRSCHLSTDNRITARAAFDSCPSWLRLQTDYYEKVTEPPPTTQPPTTTRRTTTTWRPPTRTTTKSPLPESCSTPLGLGKGSGYSLPDAAFTASSTLSLAAWSAGPENARLHQEDDYDRNRVGSWCAGSSDYGEYLQIDLGRTKRITGVATQGRPKQFEHVKSYNLAYSHDSRTWYDYMEGGYVKTFEGNCDHLTAVTNRVSEPLTARFLRFIIQDNEWPCLRAEVYGCEPDTPTAGGSYPGNDGGRVPDTTYPSNGGGRVPETTYPSFNGDHGYDDYDIYDDDDIEARIP
The following text describes a protein:
Function:
Protein kinase that plays a central role in centrosome duplication. Paternal copy is required to regulate synthesis of daughter centrioles prior to fertilization. Maternal copy regulates centrosome duplication during later cell cycles. Functions upstream of sas-5 and sas-6, and is required for their localization to the centrosome (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Component of the centrosome. Present at centrioles only immediately before their duplication (By similarity).
Sequence:
MSGGKSGTKLSSFQNLQQIGQGGFGVVYSAQRENGEKVAIKKIGNAASQTRIKEEIKTMKLLRHRNIVQFYETFFENGETYLVMELCEGGSLMDYVKQKGPLDDSTAVHILRQLIAAVKYIHDENILHRDLSAGNVFIKDATKSTITVKLGDFGLATNLGQHGTACTIVGTPGFIAPQVFGQNYDQAADVYSLGAVLYTMLTKHTPPTKGPPNLESLKKRNPSAADLVERMMHTDARRRIQLKEIVMTDYVKAKMGEATPGSREHSRDSRSQRSREPFRSSRDGISLERRPPARSSSQPVNSRRDPDGYRAAHEMPTTSRTSVEPDRARVRHRLSARGIGSSQEDDLRQQIWPIRMERLVGQRVRTPGGRYIVEMNTRCRFEVVSKGNIVLRILVVEYDPHLLIQTVYVHKMSNRVEHARNETDDLIELTRSPISYTSLSQLPKEVMNDYMRLEKMMVSTIASRVAKITHRRPSQFPDASAQLMENGDLRIRFPNSLIVRRKSNGEVHNYIDGFANNKEEVRGLQLSKVREVYACLTQLEQCLSRMNPTMKILPMVFSAGPDIVATYNNSPSSILPSTSSQASRFPFSEISSSQQLVPHSAPIPNKPLSSRTTSSLNVRNGVSSDENTAPAATRQKYKARLDPVTGRIVSVQAEDNRKLRCSTSKPDQFIFTDPSISSSEQRFMRNGRVPERASEMLHALLVYMKKKQN
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Mitochondrion.
Sequence:
MIAKQAALIRRSSSVATAASSLSPFSSPSSSSSAFSSSLLLSPARRMRQTPTSASWTPFSSSFPCSRAVSAFCFSTKGPRSQASPAAELHRDHHDQHPSVSSSTLPTQQQQVDANSSASGSLSPPSSVTASISSSPSSSSSSSSAAAAASSQSNDRRSRFMPYAFASGSPLTRLPTPLPPDVAERSYLLRKQFAPKRRSETPVAATSAMLDSRIDGLSFGDLSGLTMSSNDETFYPASRAVEFVSILKACLGTGLISRAHKVFTDLRSQATARSRELWELRKRLAQGIIDQNDWHQDLGELGQYQSPIEIWTYNSMLQAYFRKAYQAESLDGTAEWLNRAWQLWRDMQAAAAPLHNDQPPSPDPKPNPATFATMARGVVALQRSGRYPSSAPALDDLVLSIKRAEFGLDSILTSSVFNPDKAEDLDVHGPLGSKSVDQSREGEVDADLVLRSLIHVANQMGESGILKELETVQSILDGRRVLSEVKPTDSTAQNDLLADVPELLAVKTTSKASRLGQDPKNKAGEIPFNLASLKENLSIVQEARRNISDPYERQKWLEHSALEAARKRLEHSAEKLEELGLQTTGALQSKPLQRWMWDWYNKLQVTLNQELARLDQEVNENKHDRKAMLPMELQILPFLRLLPASKLALITILELMRMSGNGDVSDGMKTTRAVLQVGRAIEMEYHSDIVRKNPKIFQNAYTAQTTLRKRGLIDLAARREIKAWQKQQEDEGVLSSIPSWTQTVRARVGSYLVQHLMNVATVNRKATDRDGVLWEEDQPAFYSTYQYLGGKKLGVIKLNEVIARRLDKDSIQETLHPRHLPMLVPPKPWTSHDSGGYYSVRQSAMRYKDSAEQGSYLRVASDNGDLDTVLAALDVLGNTSWKINKPIFDVMLEVWNSGKDIADMPPVEMEVPEPQKPDNYDHDIKARSVYLQRLKQWNQQRASNHSQRCDVNYKLEIARAYLGERFYFPHNMDFRGRAYPMPPHLNHIGNDLCRGLLLFADSKPLGKAGLRWLRIHISNVFGYDKASFGEREQFAIDHEADIRDSVERPLDGNCWWLKADDPWQCLAACMELKAALEHAEGPEAYESCLPVHQDGTCNGLQHYAALGGDLAGAKQVNLSRGERPADVYSGVADLVIKVLDEEAAKGERLASILQGKVTRKVVKQTVMTTVYGVTFIGAKNQVMRQLADRGDVPAEDLFAAASFLAKVIMSCIGNLFSGAQKIQDWLSFSAKVIAKSIPAQRLEEATRPYQPNESTLKRADARGFSRDPAKADRIVKEQMTSVIWTTALGLPVVQPYRKSKKKQVSTAMQTVFIHDPLSNSEVSPAKQASAFPPNFIHSLDATHMILTALECHAAGLTFASVHDSYWTHAADIDTMSDMIRETFVRLHSQDILYRLREEFLQRYAGYKVPVVSLQTATRRRGRLSKASNDEPQDVASTAGVTSPPEALLAMPEEQLAKLQGEIGDVVIAKPTKAPDVEADEVLDNVAADASEADLAEESEFASDKAEEAPVTAPKRKSARKSQKDKDLEWETKFKAKFVDLADILPAIPAKGSFDVNEIKGSLYFFS
The following text describes a protein:
Function:
May be involved in protein transport between endoplasmic reticulum and Golgi apparatus.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MIMLSFMGFLQSCLLIVNSFAILNERFLNKIGWGVKSDLDMNSFKGKIITLLHSLRFFFRSMFSNI
The following text describes a protein:
Function:
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Sequence:
MQLRNDLSTWAAILGALVLTAGSQTSASPIHGIVDRESRNNGKQPSFYGAASQGNSAEYSVEGKHGAVSSEVDVCSNIGAQLLQQGGSAVDSIIGTALCVGSIASYHSGLGGGGHAVLRSPITNDDRTNRKRSNPNDARSKTSTYVHIDFREVFPAAATEDMYTNNPVKNASLYGGLAVGVPGEPKAWWDLHQKYGKLEWSKVFEPAITLNRRGFKVTAELAKALNTTQYPFLCKDKRWSRFYCVNGKVAQLGDTIKKERFAKTLELIASKGVDPYYYGEIADDIVDTIANNKVLKGILTKHDLANYKVEYRNPRNVTLRDGKYRLFGTVAPSSGSVVLSTLQTVDQFRVDGEEDLSNVNVSTHRLIEANKFSYGQRTNYGDPGFVKNVSRLEGEYLELPFSKENKNQISDTRTFSASHYIPDHKNAEVKSDHGTSAITVVDADGMAISLTTTINTFWGSQLMTEHGFPLNNELDDASSPGQTNFFGYLATPANYIEPGKRPLSSISAVIAEEVRTGELKLSLSSAGGSRIITAVTQVAYNVLFKGQDAQAALAEPRWHDQLSPNQTTLESAAAAIRGFVGFNNQTAAFLASVGHNVSWTPIGSSTAQAVERFPDGVLLAATEVRQLAAKGAAF
The following text describes a protein:
Function:
Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
Sequence:
MGKKIRLTTAQALIKFLNQQYIHVDGKEEPFVEGIFTIFGHGNVLGIGQALEQDAGHLKVYQGKNEQGMAHAAMAYSKQMLRRKIYAVSTSVGPGAANLVAAAGTALANNIPVLLIPADTFATRQPDPVLQQMEQEYSAAITTNDALKPVSRYWDRITRPEQLMSSLLRAFEVMTDPAKAGPATICISQDVEGEAYDFDESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGAKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDFDKAKFLNINVSRMQAYKLDAFQVVADAKVTLGKLHGLLEGYESEFGTTIRELKDEWLAERERLSKVTFKREAFDPEIKNHFSQEVLNEYADALNTELPQTTALLTINETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEFRTDDNQILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLPKTMTDGYDSWWHVGVAEVSEQESVQKAYEAKEKKLESAKQY
The following text describes a protein:
Function:
Involved in oxygen transport from the lung to the various peripheral tissues.
Sequence:
MVLSADDKTNIKNCWGKIGGHGGEYGEEALQRMFAAFPTTKTYFSHIDVSPGSAQVKAHGKKVADALAKAADHVEDLPGALSTLSDLHAHKLRVDPVNFKVEGEGVPHAQGREHSVPGRGAYPAGCLLLGTDPSLQFLSHCLLVTLACHHPGDFTPAMHASLDKFLASVSTVLTSKYR
The following text describes a protein:
Function:
Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Promotes viral cell-to-cell long distance movement by enhancing the ATPase activity of TGB1. Enhances RNA helicase activity of replication protein alpha-A. Suppresses autophagy induced by the host as a defense mechanism against viral infection.
Miscellaneous:
MISCELLANEOUS: The genome of this virus consists of three linear, positive, single-stranded RNAs encapsidated in separate virions designated RNA-alpha, RNA-beta and RNA-gamma. Three proteins (alpha-A, beta-A and gamma-A) are translated directly from these genomic RNAs and the remaining proteins encoded on RNA-beta (beta-B, beta-C and beta-D) and RNA-gamma (gamma-B) are expressed via three subgenomic messenger RNAs.
Subcellular Localization:
Host chloroplast envelope. Host endoplasmic reticulum. Host cell junction, host plasmodesma. Note=Recruited by the replication protein alpha-A to viral replication sites at the host chloroplast membrane.
Domain:
The three domains C1, BM and C2 are involved in zinc-binding. Zinc-binding of each of the motifs is critical for the biological activity; The coiled coil domain is probably involved in homooligomerization.
Sequence:
MMATFSCVCCGTSTTSTYCGKRCERKHVYSETRNKRLELYKKYLLEPQKCALNGIVGHSCGMPCSIAEEACDQLPIVSRFCGQKHADLYDSLLKRSEQELLLEFLQKKMQELKLSHIVKMAKLESEVNAIRKSVASSFEDSVGCDDSSSVSKL
The following text describes a protein:
Function:
Probable drug/proton antiporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVAEFQIASAQSSALTSTEEEHCSINSDKAAKLDLELTSERKNDGKQSHEVTFNEDIADPEDIARHMSTARRYYISSLITFTSMVITMISSSWTLPSTHIIEHFHISHEVSTLGITLYVFGLGIGPLFLSPLSELYGRRITFLYALTLSIIWQCLTIWSKTITGVMFGRFLSGFFGSAFLSVAGGAIADIFDKDQIGIPMAIYTTSAFLGPSLGPIIGGALYHQSYKWTFITLLITSGCCLVMIIFTIPETYKPMLLIRKAKRLRKEKNDQRYYAVLEVTREQTSLLSAIFLSTKRPFGLLLRDRMMGVLCFYTGLELAIIYLYFVAFPYVFKKLYNFGPMEIACSYIGIMVGMILSAPTCLLFQKTFEWRVKRNNGVKTPEMRFEPLFYGAFLTPVGLFIFAFTCYKHVHWIAPIIGSAIFGSGVYFVFTGVFAYTVDAYRRYAASGMACNTFVRCIMAGVFPLFGLQMYKSMGVNWAGFLLAMVTVAMIPVPFLFTKYGARLRAKSPYAWDD
The following text describes a protein:
Function:
Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate. In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
Sequence:
KHYIISEELISEGKWVKLEKTTYMAPTGKTGTWDSVKHTTRREQTGDDVAVIPVLQRTLHYKCIVLVKQVPCRELIDDGETPGAAALWELEEETGHKGDVAECSPVVCMDPGLSNYTTHIVTVIINGDDAENVRPKPKPGDGEFVEVISLPKNDLLQGLDALVAEKHLTVDARVYSHALALKHANAKPFEVPVLKF
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MTDIETARTVVGAIGNVIAFGLYSAPIPTMVKICKMKSVAEFMPDPYIATVINCMMWAFYGLPFVTPDNILVITNNGVGLVMELVYVIIFFIFATSPVRKKITIAIVIEVIFMAVVVFCTLYFLHTPKQRSMLVGILCIIFNVIMYAAPLTAMAQVIKTKSVKYMPFSLSLANFMNGAIWIVYSYTDSLFVLRGYLDKEITEDSSARQSKMTSRRGVTKDQVMIELVIRDDHCLDTQWNLTSDFTGSLERKAKGGVVSSIKPNLSHIRNKNDKTLKKYIYIKKKEKSNK
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
Sequence:
MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNPETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEVTFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSGLMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETETNYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTVHAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQLEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKACELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPAEDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE
The following text describes a protein:
Function:
Possesses low quercetin 7-O-glucosyltransferase activity in vitro.
Sequence:
MGSSEGQETHVLMVTLPFQGHINPMLKLAKHLSLSSKNLHINLATIESARDLLSTVEKPRYPVDLVFFSDGLPKEDPKAPETLLKSLNKVGAMNLSKIIEEKRYSCIISSPFTPWVPAVAASHNISCAILWIQACGAYSVYYRYYMKTNSFPDLEDLNQTVELPALPLLEVRDLPSFMLPSGGAHFYNLMAEFADCLRYVKWVLVNSFYELESEIIESMADLKPVIPIGPLVSPFLLGDGEEETLDGKNLDFCKSDDCCMEWLDKQARSSVVYISFGSMLETLENQVETIAKALKNRGLPFLWVIRPKEKAQNVAVLQEMVKEGQGVVLEWSPQEKILSHEAISCFVTHCGWNSTMETVVAGVPVVAYPSWTDQPIDARLLVDVFGIGVRMRNDSVDGELKVEEVERCIEAVTEGPAAVDIRRRAAELKRVARLALAPGGSSTRNLDLFISDITIA
The following text describes a protein:
Function:
Involved in carbon catabolite repression. Represses the transcription of various genes including the inv1 gene.
Subcellular Localization:
Nucleus.
Sequence:
MSEATTATTTGKPSRSTKNPDAPRPYKCPLCTKAFYRLEHQTRHIRTHTGEKPHVCTFPGCAKRFSRSDELTRHARIHTNANSRRNAAAAAAANNSARSSNSPAGNLEPSTNNAGVHMTNASMNPNVNPSYPVFIPQVGMSVAPPVATAAVSMSYPHHYSASVQQQQATFVSNGQPHNLPAQAQPATIYGIPDALHTTQNGTTIHVTGTPPGAVSQRSEPDSRLSSMNEMQLLASAAANQLDAAPRITPTKSSGVNLMPLSNAPSPPKQMNVVGSLPSSSNTSPNHLASVPNRGLTSNSSTGSFTKYTNGSSNSLYSNSSMQTPYLPSKSNSSTSLHSMYGVGTTAYAPQSLRYAHYNYLPYSRPSVSNGFDDDSSSSDFAHFRYQRRSRPVSPCSTAPSSPTFSTRSFSPTPDVTPLVTPAHSPRLRPMDDPSCVQLPSIRSLSLRPSQVPLIPPLKCDPNAFSASTPASGAVSRTPSSVSLSSLSNVNSSMPHKPASQSNVGPVRISSNRRSRKFSSSSRVSVSNLLAGSPPSPSSSTKSASSSYSTTTPAFSIGPLTPMTKP
The following text describes a protein:
Function:
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
Sequence:
MKENKIRKNKEFRHVYRRGKSYSNRLLVLYICKNRCNINRLGVSVSKKVGKSVIRNRVKRLIKESYRLNLDENMKKGYDLVFIARNSSNDRDYKDIESALINLLKKAGIYN
The following text describes a protein:
Function:
Component of the ribosome.
Sequence:
MAKDKKQQKKPSKKTPAPCPLSTKVTVKKEIKKEKKTGIKDNPLIFEKKKRSNIIGVGVRPKKDLSKYVKWPRYIRIQRKKKILLQRLKVPPSINQFNHTLPKSQTQDLLNFLKAYKPESKTDKKQRLLNKAKEALNKNITKDKKPLFLKYGINHITKLVENKKANLVVIANDVSPIELVLFLPALCRLKEVPYCIVKDKATLGKLVHKKTATAVCLESVKKEDQEKLDYFAKVCKENFNDNVDLRRKWGGQKMSAKSMLLKKMKDKARKIEEAKKKEISAKL
The following text describes a protein:
Function:
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MKGISLSPSNHCQLKFQNILAKQLNKPINTIPFHFTITNRQFPAHVIKCQCQRRDQNPVPKNPINTPPPLVVVGSANFDIYVEIDRLPKVGETVAAKTSQTLAGGKGANQAACGAKLSHPTYFVGQVGEDANGKLITDALSGCGVRLDYMNVVKDGGVPTGHAVVMLQSDGQNSIIIVGGTNMSCWPEKFGDEDLEVVKKAGIVLLQREIPDSVNIQVAKAARSAGVPVIFDAGGMDAPIPQELLNFIDILSPNESELGRLTGMPTDSYEQISEAVVKCHKMGVQQVLVKLGAKGSALFVEGEKPIKQSIIPAARVIDTTGAGDTFTASFAVGFVEGKSREECLRFAAAAASLCVQVKGAIPSMPDRKSVLNLLQYA
The following text describes a protein:
Function:
Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by mediating the conversion of 3-(methylthio)propanoyl-CoA (MMPA-CoA) to 3-(methylthio)acryloyl-CoA (MTA-CoA).
Sequence:
MTYQAPVRDIMFAIEHLSQWPQVEALQTYSEIELDDARAALEEFGRFCGEMIAPLSTIGDTEGARLENGRVVLPEGYKTAYDQFVDMGWQSLSHPAEHGGMGLPKVVGAAATEIVNSADMSFGLCPLLTNGAIDALSITGSDAQKAFYLDKLITGRWSGTMNLTEPQAGSDLSRVRCTAVPQDDGTYAISGTKIFITFGEHDLSENIVHLVLARTPDAPEGVRGLSLFVVPKLLAGEGGETSQRNTLGCVSLEHKLGVRASPTAVMEYDNATGYLVGEENSGLRYMFIMMTSARYAVGVQGVAIAERAYQHALSYARDRIQSRPVDGSAQDAVPIIQHPDVRRMLLRMRALTEGGRALAIATGGWLDLAEHGPEEARAEAQSMAEFLVPLVKGFCTERAVEVASLGVQIHGGMGFIEETGVAQFYRDARILPIYEGTTAIQANDLLGRKVLRDGGRTARRFAEMIAATEGELSKGGAAAQRIAQRLAEARAAFAAGLDHLLATAGQDPNRAYAGSVPFLMLTGNLATGWQLGLSALAAEAELAKGGDAEFLQAKIATADIFAQQVLVECSAEHSRITDTGDSLLTASL
The following text describes a protein:
Function:
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
Sequence:
MASEKKVVFLRSSDGEAFEVSEEVISAASVTIKGMIDEESPSRADTAATTTLAIPNVTAATLSRVLHYVNKHFDAAAVVGRPDDYIFCAPGDEHPLARFDDDFVDVDNDTLIDLVHAAEYLHIKKLFDLTCKAVADKLKGRTIDQIRETFGIVNDYTVEEEVEVYRENSWAF
The following text describes a protein:
Function:
Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.
Subcellular Localization:
Nucleus membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Sequence:
MSNGAFDAIFEYAWGQIDKPISGDFIYGKDLPKLIEIIENIFQKAQKSGSYELRLPLFSEINKDLFRTFSNTKTFFKIHKEEFDDIFFNLVNHPLREILENAFIGVDSIPSDFIVSMNLNSPSKFLVENKNKNTEGAGISTPRKKLTESPIKLLSRNNIGKALEVQVEELKRELTAKQSLLQENERQVSELKIRLETYQEKYASIQQRFSDLQKARQVEDNQNSSRTSDPGSPLVTGIDQKAILEEFRRRLQRQTDTISFLKDQIRRERGLNCSNDKVSHSKRKHATTDGDGTFKNFISAVPSNIWVKATIRIIVCFALLAGVLPYIRKYVYAHDTPSQNSRLQLSWWENSGILSKIVWFFEDQTDLETEYRSNANVDDAYSRVFGI