lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Defense against chitin-containing fungal pathogens.
Sequence:
MKTTLSTLLLAGLFLAGIIVPEPVASQNNVNRADIVTQEFFNGIINKSPNTCRGKSFYTRVAFLRVIGDYQEFARSGSMDDSKRELAAFFAHVTHETGHFCYVEEINKQEYCDRTRNAYPCAPNKRYYGRGPLQITWNYNYGAAGSSIGSDLLGNPDIVANDPMISFRTALWFWMTNVHSVVGQGFGATIRKINGGECNGGNAGQVSSRVAYYTDYCNQFGVSPGPNLRC
The following text describes a protein:
Function:
Endosomal/prevacuolar electroneutral Na(+)/H(+) exchanger which mediates intracellular sequestration of Na(+) cations, regulates vacuolar pH and contributes to osmotolerance following sudden exposure to hyperosmotic media. Also contributes to the postdiauxic/stationary phase resistance to osmotic stress and allows for the continued growth of cells until the acquired osmotolerance response can occur. Involved in hygromycin resistance probably through its influence on the electrochemical proton gradient affecting secondarily the entrance of hygromycin. Mediates pH-dependent vesicle trafficking out of the endosome. Contributes to K(+) sequestration and homeostasis.
Miscellaneous:
MISCELLANEOUS: Present with 521 molecules/cell in log phase SD medium.
Subcellular Localization:
Endosome membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein.
Sequence:
MLSKVLLNIAFKVLLTTAKRAVDPDDDDELLPSPDLPGSDDPIAGDPDVDLNPVTEEMFSSWALFIMLLLLISALWSSYYLTQKRIRAVHETVLSIFYGMVIGLIIRMSPGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNMLSILIFAIPGTFISAVVIGIILYIWTFLGLESIDISFADAMSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHGQPATFSSVFEGAGLFLMTFSVSLLIGVLIGILVALLLKHTHIRRYPQIESCLILLIAYESYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRSQITIKYIFQLLARLSENFIFIYLGLELFTEVELVYKPLLIIVAAISICVARWCAVFPLSQFVNWIYRVKTIRSMSGITGENISVPDEIPYNYQMMTFWAGLRGAVGVALALGIQGEYKFTLLATVLVVVVLTVIIFGGTTAGMLEVLNIKTGCISEEDTSDDEFDIEAPRAINLLNGSSIQTDLGPYSDNNSPDISIDQFAVSSNKNLPNNISTTGGNTFGGLNETENTSPNPARSSMDKRNLRDKLGTIFNSDSQWFQNFDEQVLKPVFLDNVSPSLQDSATQSPADFSSQNH
The following text describes a protein:
Function:
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Miscellaneous:
MISCELLANEOUS: Yeasts contain 4 individual small ribosomal A proteins (RPA) which can be classified into two couples of similar but not identical sequences. Each couple is distinctly related to one of the two A proteins present in multicellular organisms.
Subcellular Localization:
Cytoplasm.
Sequence:
MKYLAAYLLLTVGGKNSPSASDIESVLSTVGIESESERVEALIKELDGKDIDELIAAGNEKLATVPSGGAAAAAAPAAAGGAAPAAEEAAKEEAKEEEESDEDMGFGLFD
The following text describes a protein:
Function:
Digests double-stranded RNA. Involved in the processing of ribosomal RNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Removes small helical intervening sequences (IVSs) from all 7 of the 23S rRNA transcripts. Probably also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
Miscellaneous:
MISCELLANEOUS: This organism contains small helical (90-110 nucleotide) intervening sequences (IVSs) in all 7 23S rRNA genes at either the 550-bp or 1170-bp positions or both, accumulating the 23S rRNA as 2.4, 1.7, 1.6, 0.7, and 0.5 kb pieces.
Subcellular Localization:
Cytoplasm.
Sequence:
MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSFVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFDLGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSNIQTVEQLILNWYKTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
The following text describes a protein:
Function:
Has a role in pre-mRNA splicing where it is involved in spliceosome assembly.
Subcellular Localization:
Nucleus.
Sequence:
MSRRSLRTLYVTGFRDGMRARELAYEFEPFGPLIRCDIPIPRTRTSRPFAFVEYEDSRDAEDAYYEVHGRRLERGGGVLRVEWAKQPPPSGPGSKRGGRRERGGRVHGDSGRLRSRSPSPHEARSRSPYNDERSDRRSMSPRYRSRSRSPDGRSRSPDYDRRSPKRNHRSPSPVSFAPQKSPVENETETNVDNGDTKISESNEKSGTEVEQQSAPNSNGNEEVNNLEPVGQNESKQEPPKEENSNVSQEQPEQAQPEVSAASEQPESNPTTTESQ
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
Miscellaneous:
MISCELLANEOUS: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNWLEAFILGIIQGLTEFLPISSTGHLYLGRHLFRLDEAGLFLDTMLHIGTLLAVFIYYKKEFIYLIKNPFSKLMLLLIVGTIPAVVIGLLFKDFFEDISKTGITIGWEFLVSGFFLYMADKQKNGRKKMDDITYKDALIIGSFQAAAIFPAISRSGMTIVAALWRKLDRETAAYFSFLLSTPAIVGAIILQFVDVFQGKAESISSTSLIVGTLSAAFFGYIAVSWMIQYLKRHSLKVFAYYVWGLGILILMLQFTDVF
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSIYIQLTHDLSGTVTAVTIGDWILGILKEKNIQEYEVFFKKFLHIYQKQDKDSECNNRSEIFSLLLSASDFVFETLVETKKNNKIKVIIDNKESVKSYNEFYKEVEEYFVILISILQLEFKSVEELNNATNNFIKAIKNYNEFPELRLKILQLLYNSFNVNFSFRFPTFIAILQFCSQNNIFHNMLPYIKYIDDWIKEWNISTREKRHIYLIISQELKKLKKYEESYEHLKKHIYYYDNEHKDILNHPNSINASIELIVDAININNNIYFHEIINLHAIQNLQFIPQHQPLFDLLLIFYKYTINEFLVFKNKHGSDFFNKYNIDIQTCESKIYLLSIISLFNDHKVQNIQFISKQLNISVVQIENILVAAIGSGVIDAKIDQINQTVHMKTTILRNFDDENWKQLNNQITKYINNVQKILELTKHANK
The following text describes a protein:
Function:
Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for stem-loop (SL) and splayed arm Y structures. Introduces a single-strand cut in duplex DNA on the 3' side of a double-strand/single-strand junction with respect to the single-strand moving 3' to 5' away from the junction. Plays a critical role in maintaining the integrity of the ribosomal DNA (rDNA) loci, where it has a role in re-starting stalled replication forks. The complex initiates homologous recombination (HR) events, used to maintain rDNA copy number, in the rDNA repeats that are processed by a mechanism that requires rad22, but not rhp51. Has Holliday junction resolvase activity in vitro. Slx4 is required for efficient processing of DNA substrates.
Miscellaneous:
MISCELLANEOUS: Simultaneous elimination of slx4 and rqh1 is lethal.
Subcellular Localization:
Nucleus, nucleolus. Note=Associates with chromatin at rDNA repeat protrusions.
Sequence:
MSAEEYIEVSSSPDIFTDDDDMITIEPELNKNPKDCNSKRKRSVTECCEIRLITSKCDFESTQQLVHHNCTGHKVHEHNLNAVDEEDFDTENLPLLFSSFSDNESDILEPDLNTRVAEDNDVLLSRYSKIKNSASCRNTFEHSAYHSNREEISSSGFYYHRKPQLFEKSLEKLGNKSIEANRSPLIKELCESANSTENVCFSVSTVDEIQQRHPSAGHSIDSTCQSNSFLEGDSATHKKKKTDNIKEFTSCEFNDRSRTLLNYAGYMDTNKNADNEAKSLKEKLENFPVEKLRAIAESYGFKSSDSKATLIKIVESCLDAIDSRSQSKKLGKETPHDYLITSTKTVLEFDDIVTQTHRAISQVVKQAKDNSVWIKILTYSAIDVEEFQLWLKRKNLNVSLDLIKSWCDKYGVLMKGSWH
The following text describes a protein:
Function:
Component of the GID E3 ligase complex recruiting N termini and catalyzing ubiquitination of proteins targeted for degradation. GID E3 is regulated through assembly with interchangeable N-degron-binding substrate receptors induced by distinct environmental perturbations. Required for the adaptation to the presence of glucose in the growth medium; mediates in association with the substrate receptor VID24/GID4 the degradation of enzymes involved in gluconeogenesis when cells are shifted to glucose-containing medium.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MVGTSSLDISMSGSSSSDAEQWEKQTKSVHIDNSDVNSLILDYLVIQGDEEAAKTFAEEAQITDYYIPPYVKERLEICELIKSGSINSAICKLNELEPEILDTNSELLFELLRLRLLELIREVVEEKDTSDLAVERCLNFAHENLAPLAPSNQKFLNSLELTMSLLCFPPSSYSPALKNVLNYSQRERVANLANVSILKSQGLSNESRLLSLVNFERWCEKEAQRNSIEVQKFVPKASIK
The following text describes a protein:
Function:
Involved in the degradation of isopropylamine, which is a constituent of the herbicides atrazine. Catalyzes the ATP-dependent formation of gamma-glutamyl-isopropylamide from isopropylamine and L-glutamate. It can also use aminoalkanes, amino-alcohols (L-alaninol and D-alaninol) and amino-esters as substrates.
Sequence:
MSEENKKQILKVRDFIEKHNIDTIRLGAVDIDGVWRGKQVGAEYFLNKAALDGTQISNILFGWDVADHLVDGLEFTGWDSGYPDIALIPDLSTLSLVPWQEKTASVLCDIQHLNGEPLNLSPRNLLRKAIEKAEQLGYKCYAAYEFEFYLLNDSIASISADQWRSINPVEKSGHCYSMLHHSSSSDIMGEVRKYMRDAGIVLEATNSEHGPGQYEINIKYDDALKAADDAIFVKNGIKEIAAKHGMTATFMAKPSAEWSGSSGHVHMSLSDLAGTPVFANPENPGALSEVGYNFLAGMVALAREMSAIYLPNINSYKRTAGASWAGGNSSWGFDNRTVSHRAITSAGSAARVENRIPGADTNPYLVIAASLLSGLYGIENKLKPKDPILGNAYKVSPELARPLAASLEEAAGIFRESEMARVIFPNEFVEHYAQMKVWEIKQSNSFVNNWELARYLDII
The following text describes a protein:
Function:
Specifically catalyzes the removal of N-terminal proline residues from peptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MNLILASFSLAPCFCVRFFPSNHNNLNLLFPGQRKIQVSCGGKSEVLKSDTMEPHEAETFVNKRTLYAPIEPYSSGNLKVSDVHTLYWEQSGKPDGHPVVFLHGGPGGGTAPSNRRFFDPEFYRIVLFDQRGAGKSTPHACLEENTTWDLVNDIEKLREHLKIPEWLVFGGSWGSTLALAYSQSHPDKVTGLVLRGIFLLRKKEIDWFYEGGAAAIYPDAWEEFRDLIPENERGSSLVDAYHKRLNSDDLEIQYAAARAWTKWEMMTAYLRPNLENVQKAEDDKFSLAFARIENHYFVNKGFFPSDSHLLDNVDKIRHIKTTIVQGRYDVCCPMMSAWDLHKAWPEAELKIVYDAGHSANEPGISAELVVANEKMKALMG
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. Binds to polypyrimidine-rich controlling element (PCE) of CFTR and promotes exon skipping of CFTR exon 9, thereby antagonizing TIA1 and its role in exon inclusion of CFTR exon 9. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to a polypyrimidine tract flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.
Subcellular Localization:
Nucleus.
Sequence:
MDGIVPDIAVGTKRGSDELFSACVTNGPFIMSSNSASAANGNDSKKFKGDNRSAGVPSRVIHIRKLPGDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGLSVPNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKPVRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKILFSSNGGIVKGFKFFQKDRKMALIQMGSVEEAIQALIDLHNHDLGENHHLRVSFSKSTI
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MEKQQPGSSDHGGKCQTDKLSEEIVQSDKLSEEILLAKSGLVNSISTLTLLDQRNSEESSDSIYANETNDVSLTIVKTPVSQLRKKLLVLDVNGLLADIIYRPSKNYKADAHIAGRAIFKRPFCDDFLRFCFEKFEVGIWSSRNRRTLERVVDFLMGDMKQKLLFCWDSSHCTTTQFKAPGHRYKPLVFKELRKLWRKSDPNLPWEKGYYNESNTLLIDDSPYKALLNPLDTAIFPHPFMFDMDDDSLGVGGDLRVYLERLALAENVQKFLELNPFGQIAITERSHDWCFYGRVIDTCVHSQLQQLNV
The following text describes a protein:
Function:
Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Limits class II meiotic crossover (CO) formation by regulating the invasion step of meiotic HR. May counteract DMC1 and RAD51-mediated inter-homolog strand invasion to limit CO formation. Functions independently of FANCM.
Subcellular Localization:
Nucleus.
Sequence:
MCGSVVSDSEREFEFHFWGFGHLGKEEERIMAGKRSSPFSSPLLRPPPEFLNVKEEGETETPCWRKEVDENLKRLQSLLFGADKFLEKSDFSSAQILGLRLLGFLDSRSVTDADRDFIGPIRREVASKIDLALEGLVSDSDRKAFELANTAPGAIFGSKGGFDVEKIKQSKYFGFHVSQSNGKGVKEMEERHDTDKLIPKAPKSMMQAKLTSLYGNSIGKPDNQRKTSVNNQDRASDECVIVERSHGFGFGTKRPHAETSSLANDGEVKEDGAPNGFVSAKIKLEMDVRQKRGSTESPSSCLSPQSDKNALGRGYGSRSGGLRRGYRSNFVPPVKTNGNNVGNLTSRIGGKTDDALDDSTRTCLEMLCGPDGELPEKLRNLEPRLIEHVSNEIMDRDPNVRWDDIAGLEHAKKCVTEMVIWPLLRPDIFKGCRSPGKGLLLFGPPGTGKTMIGKAIAGEAKATFFYISASSLTSKWIGEGEKLVRALFGVASCRQPAVIFVDEIDSLLSQRKSDGEHESSRRLKTQFLIEMEGFDSGSEQILLIGATNRPQELDEAARRRLTKRLYIPLPSSEARAWIIQNLLKKDGLFTLSDDDMNIICNLTEGYSGSDMKNLVKDATMGPLREALKRGIDITNLTKDDMRLVTLQDFKDALQEVRPSVSQNELGIYENWNNQFGSLSL
The following text describes a protein:
Function:
Potential calcium-dependent cell-adhesion protein.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MKHVRHFIPSLFLSLVHVCLVQANYAPYFFDNGARSTNGNMALLSLSEDTPVGSHVYTLNGTDPEGDPVTYGLTYEAGSRRYFSVDGNLGNVTLIEELDREKEDEIEVIVSISDGLSTVSEKVRILVMDANDESPEFINTPYIVQVPENSPSGSSIFKIEAVDRDTGSGGSITYFLQNIHANKFTIDRHSGVLRIKSGVTLDYEKSRTHFVVVVAKDGGGKLRGDNKVFSATTTVTVNVEDVQDTPPMFIGTPYYGYVYEDTLPGSEVLTVVALDGDRGKPNNIHYCIVNGSEGSFEISNTTGAISVIKSPNQLKKEVYELRVQASEVSPEGDVSAYAFATVTIRVVDLNNHPPTFYGESGPQNRFELTMYEHPPEGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPLTVLNEAQVTIIVENSAAIDYEKFKVLTFKLLAIEVNTPEKFSSTADIAIRLLDTNDNVPKFSSDYYIARIPENSPGGSNVVAVTATDPDSGLWGEVKYSIYGTGADLFLIHPSTGIIYTQPWAVLDAEVNSKYNFYVKAEDTDGKYSLAEVFITVLDVNDHSPEFNENIQEKTMIIGSPVKIEAIDQDAEEPNNIVDYSIMQADPANVFDIDQSTGEIKLKSYIRSLDIIHNITKNKDCIWSLVVQAKDRGSPSFSTTAVLKIDITEETLHKGPMAAFLMQTKDNPMKALGVLAGVMGIMVLITIMISTAMFWRNKRSNKIMPVRRIIKKRQTQQSRTVRMEWLKFKRPSNAAEKFVVEDDAKSLQNENSNNNVQAAPVPPAAPLPPPPPALAASGNTTAWRVPTVSGSLTPKFINKQLKKRGHSSTHNALVSELKMKFEKRNASMGEPHI
The following text describes a protein:
Function:
Acts as an essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity. MIND plays a role in establishing a bipolar spindle-kinetochore interaction by joining kinetochore subunits contacting DNA to those contacting microtubules. NSL1 facilitates the attachment of two of the DASH complex components, DAD2 and SPC19, to the kinetochore in a microtubule-dependent manner.
Miscellaneous:
MISCELLANEOUS: Present with 3710 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
Sequence:
MSQGQSKKLDVTVEQLRSIYHQFHDILEEKTDLHLPKKEYDDDAVRREVQIQLQEFLLSAMTMASKSLEVVNADTVGKTVKQLIMESQEKYMEPFDLDLNEQVRKMYQEWEDETVKVAQLRQTGPAKINEVYNNSKDEYLAQLDGRIGVLQARMMQQQSADHDDSTDDADDHINWEHIKQDYVASLNELYQTQQDLPKVRYNVEKVKRLMDFLEED
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that is required for the plant C/N response during seedling growth transition. May be involved in the early steps of the plant defense signaling pathway.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.
Sequence:
MDPIKHISLPVLVLFLLLSVSAGQPGTPDQRHDPYAYSGSLSPAMAVVVVVVIAALFFMGFFTVYIRHCTGAVDGSVTPAGGARRRVTNATVARGLDAETIETFPTFVYSEVKTQKIGKGALECAICLNEFEDDETLRLLPKCDHVFHPHCIGAWLQGHVTCPVCRTNLAEQTPEPEVVVETDLEAQQQSAVPVPVVELPRVKFPRSHTTGHSVVLPGESTDRFTLRVPEELRKKIMANWKLNRSNSVFVLPRGGSSRSGKQVDRSRAKSDRWLFRKTPSFLWRNRDDGSIRLGGTGSVRGNSVTSPSGDSVRADRWAFLRNPSFLWRNTTPVPSPRVEVNNKDGEGTSSVQHIGTVGSTSGSLRLPV
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFEGRDVQHLRKLQLYQSFQLYLRCAQLLSNVPCCLARDLPSRAYFKQARCLLTAGTFIWVILCCYQATVKLLELPIPFFTAVLYVNEMVLNLCITVQTMLRGYSETVRYSQCLERIVTVAATVSSSEWTELLLYLRLRLYWFGIFFTLTSGVGLAVAHLFFGGIWSTLFTMGAYVLPNMLASMSLAQYYAGTVLIYKLQHTVNQQLRTAIGKHRAVRLQEIKHLYLQLDHCVQLMTRSYEVAIVTNVFLAINVTSLLLLEIYQYLQANELQANSIYIVSNVMWLALYICLLLMVLYPCDMIKREQMRFGTILFELSHSGKAATVGEDQQMALLRLLTLGRKRIVPTACGLLKLELSSLSSIFVALLSFMIILIQFDSAKLNKRDGRVTAIDQLYTPTNS
The following text describes a protein:
Function:
Catalytic subunit of the TRAMP complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information. Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates like cryptic transcripts generated by RNA polymerase II and III, or hypomethylated pre-tRNAi-Met. Polyadenylates RNA processing and degradation intermediates of snRNAs, snoRNAs and mRNAs that accumulate in strains lacking a functional exosome. TRF4 is also required for proper nuclear division in mitosis, DNA damage repair and sister chromatid cohesion. Involved in the regulation of histone mRNA levels. May mediate mitotic chromosome condensation.
Miscellaneous:
MISCELLANEOUS: Present with 7550 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MGAKSVTASSSKKIKNRHNGKVKKSKKIKKVRKPQKSISLNDENEVEILPSRNEQETNKLPKDHVTADGILVLEHKSDDDEGFDVYDGHFDNPTDIPSTTEESKTPSLAVHGDEKDLANNDDFISLSASSEDEQAEQEEEREKQELEIKKEKQKEILNTDYPWILNHDHSKQKEISDWLTFEIKDFVAYISPSREEIEIRNQTISTIREAVKQLWPDADLHVFGSYSTDLYLPGSDIDCVVTSELGGKESRNNLYSLASHLKKKNLATEVEVVAKARVPIIKFVEPHSGIHIDVSFERTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVHTGGLGGFSIICLVFSFLHMHPRIITNEIDPKDNLGVLLIEFFELYGKNFGYDDVALGSSDGYPVYFPKSTWSAIQPIKNPFSLAIQDPGDESNNISRGSFNIRDIKKAFAGAFDLLTNRCFELHSATFKDRLGKSILGNVIKYRGKARDFKDERGLVLNKAIIENENYHKKRSRIIHDEDFAEDTVTSTATATTTDDDYEITNPPAKKAKIEEKPESEPAKRNSGETYITVSSEDDDEDGYNPYTL
The following text describes a protein:
Function:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MSGLENGDVALANMTNAPDPVAAAEPYAILRQEVELDINFREKSVSGICTFKIYPLVPDLEELVLDTRQCEIDVSNITVDGYKTRAQAHDPYDRMEPPTNAQIGATQHHIMKKWMAPLLPETRRQAPIVERAEQLNISVPADGSLRIRLRPDALIQDSEPKRILKIKTPKSVSENATGLSDPNEELTVVVPFRSKRIRDGLHFVGVEEGDLRYPHVYTRHSLEPGTASCIFPCLDDPGSRHSWTIKITCPRTLEDAFAPPLATQSALLTALDGGRKRKASDISAHQPGSSFTEEDKLREITVVCSGNLIGEQMHPKDERKKTMIFECVNTAARHIGFAVGPFEHVDLGAEFRTEEADEKLGANAARIHGYCLPGRVDEVRWTCQAVVAAADYFAPEFGRYPYEAYKMCFVEDLVHDTAVANSLSLCSTRLLYPETIIDTDIEVTRKLVHALASQYVGVHIVPNERSDTWLIIGLQWFMTDLFMRTICGNNWYRFHIKSLSDKLVEADVRRPSLHALGDYLHLGDFELEFMALKAPLVLYILDQRMSKIPGSTGVVRVLSQMVSAANISNTDPKATTLSFQDFRRWCEKRSQYVPDELWNQYVFGAGCPRLDIHQKFNKKNLNVDIQILQYQGPTKKSISKDEFWRELQEEIHQVYAGDVPKLFTGPFTVRIHEADGTPYEHYQLITEKDKGGTNLQIAYNTKYKRLKRTKKAMAAAANSNSDKHEIQEDDVVYFNMLGDVLTSQKDMEDWGLQDWASEVQTKMDQESYEWIRLDANMEWLCFMKTDMQEYMYLAQLQQDRDVVAHQDAMLAFKREKRHAVHSTIETRTVMDRRYYHGVRVMALEDLAKQAHPDLNYIGMVHLILCFRKFFCKKVPIPGREGGYHYPIAPNDFTDKGQYAIQCAIPAVLARTTDLQEKGRCSKRARQFIMEMLLFNDNSENEFSDQFYIAKLLDALTTSVIPQKEITEGYLIKNLDPFDEDDAEFKSFIEKTIEEIDKFRRMDEWTLTYQNIWTTTALHCKMRLMKARVIPESALDFVQYLQDDNIDLVRIKAFECLVELGMISKPPILKLLLSYMSTDSSPFIRDRLFKVFCRGIAAIAFGENKASTQELEALNDGGLVIDQGDAEIQQRKLDAVRREDIAHALNALKEELRGNTEMQISIWKAFNSPVIGLQEKRQLLELCSAMFEPEDSLLVTIKYPIVWKATRDPTIVATAPQILGTPPKKRCVVKFKSEYRTLPKSKDMVAIEAPPPPAPLPAPTPSTNLSASRVEIKPPEKKTIVKLQSRPSYIAKPRESPVPEAPPPVRKDSIAMTVPPRPSTTAGPRTPLPTSVPSAPAPNTSAAQPSIKTAVPKAASPPPVPAPKPQQSNDVAVPRPSTVNLGKPKIVKPVIKRKSDESFENPSPKKIIKTNSDSFRSDPSRNSSFKTEPPRSESFKKEAPRSEAIRGHSFRESAPQIPPPRTSSFSVRPNANGQPSKVVTLPFRKWTKLSARAQRSIDYEQSQREKQMLAASARGISGSLATPVHKRSSAAVGFGSGSAPSSPKSRMQSPAGNGYGSSGSYAEKEQRNKERDRDRERDRDRERDSSSKFREKDRNDHDRERYRGGAEREKEKYRERERDRESDREHERPREKERDREKYRERGDRDSDRERDRPREKYREKGTDRGDSDRGGRTTDSDRERNRIDRDRDRDRERERERSDRDRERTDRERERIRDKYRDRADRDSDRDRDSYKDRDRERDRDRDRDRERDRGDRGDRGDRDRDRDRDRDRGDRDRVSSSGSSLLIKKDRKPLPGSGEKERRPLPTGAPHEKAPHPLKESHSPIHPTPAATTNGGEPKKKIIKLKLKSSGSGLGGGSGSSSTPGAGGGSGSR
The following text describes a protein:
Function:
Adds a GalNAc residue on to the Und-PP-Bac2,4diNAc-GalNAc disaccharide in the N-linked protein glycosylation pathway. Transfers the third sugar in the heptasaccharide biosynthesis.
Miscellaneous:
MISCELLANEOUS: N-linked protein glycosylation in C.jejuni consists in the transfer of a heptasaccharide (GalNAc-alpha1,4-GalNAc-alpha1,4-(Glcbeta1,3)-GalNAc-alpha1,4-GalNAc-alpha1,4-GalNAc-alpha1,3-bacillosamine) from a membrane-anchored undecaprenylpyrophosphate (Und-PP)-linked donor to the Asn side chain of proteins at the Asn-X-Ser/Thr motif.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MQKLGIFIYSLGSGGAERVVATLLPILSLKFEVHLILMNDKISYEIPECQIHFLECSKPSENPILKFLKLPFLALKYKKLCRNLGIDTEFVFLNRPNYIALMARMFGNKTRLVINECTTPSVMYMKNNFNSLVNKFLISLLYPKADLILPNSKGNLEDLVQNFSISPKKCEILYNAIDLENIGQKALEDIALKDKFILSVGRLDKGKNHALLIRAYARLKTDLKLVILGEGVLKDELLALIKELNLEEKVLLLGFDNNPYKYMAKCEFFAFASVFEGFSNVLIESLACSCAVVCTDHKSGARELFGDDEFGLLVEVDNENSMFQGLKTMLEDDKLRKAYKNKAKTRAKAFDKVKIARDALKYLLG
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MASCNGEVTTCKDKKKLRKRKKCVPLDKVDGLDNCPTNDSCLMRNTSLEKDTVRDPAISNKDESDITESQSNLESTCSQTSKRKRKRIKKNKKKNEENAKENQNMQIDIQGDTSSIKGDSVGTNLCQESAVNTDEKADSKIAPHSQLTKTQRKKMRKKQKLLASRIDDKAHVPLAELNSVKMEENALISERQSNSLGSQSASSIKKHDNNGEGGLLLAEKENIQTRQMKGTLRIYRKRKSSDSEENIVPVTLARQASSDLNNIHSFEVSENEAERVQARECASSIKVAENFLTENTSSNCSVGEFASVESNKITEVKDVDLDVHIKDNLPQVSYSSVTELHVDRPDKKLLILDVNGLLVDILPYGHISNKADITISHKSVFKRPFCDDFLQFCFKKFNVGVWSSRTKKNMDKVIDFLMGDSRHKLLFCWHQSHCTNTGFTTVENNSKPLVLKELKKLWDKFDPRLPWNKGEYDESNTLLLDDSPYKALRNPPHTAIFPHTYCYKDAGDSSLGPGGDLRVYLERLAEAQNVQDFVAQHPFGQRAITKSNPSWGFYKKLLGVASRQRQVVASGSGNTI