lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MIVEKPTWLRHAGLQIFSVDTQPNGLRFATAGGDHKVRIWNMKPLAEKETDSDTKLLATLRDHFGSVNCVRWAKCGQKIASGSDDQVVYIHEKRPGSGTTEFGSGEPPDVENWKVLLTLRGHSADVVDLGWSPDDTQLASCSLDNSIRIWQTSTGALLSVLTGHQSLVKGLTWDPIGSFLATQSDDKSVIIWRTSNWSMVKKVEGPWEKTVGSTFFRRLGWSPCGHFIATTHGFQNPSHTAPVLERGEWMASFDFVGHNAPVVAVRFNHSMFRKVKKAPADGAVDVAGNGAILGAANGTSSKTKEPPPYNVIAIGSQDCCISVWTTGSPRPVFIGKHFFQQSVVDLSWSPDGYTLFCCSLDGSVASFQFERKELGEKISDAEMEEFKKSRYGDLRVRQATVAESPAQLMLEAAAAKQWGSGNASNANTIDSTKAVSQAENGAVTAEVPKKVLTKPPSAPAPEVPIKVPTKPPSAPALGADVRNGSLVPSVPLLTPRVNPSPVKQTEYRRADGRRRIIPEPLGPPRGDDVFGNGALHSTIKNDSVTITADARKEDLGSIGLKSSESAFKRKLPEDYVKPDMPPAKRSNGSALNEALAPAACCSSAAVVAIGVGNEGPPNIASGGVQADVVVPAEKMTTPEGVLSIRIREPEGAGGEDSKNRAPIYLEARPADCTSNLGSVLGSTAPISIRESSAKAKIICSQGGEVRWCDYLVSMPTALAGNSNFWAVACGDGSLQIYTKAGRRAQPSLMLGSAAAFMDCDENWKLMVVTRNGSLYLWDLQESRRLLHESLGPLLNSTSANSMLASNGTMKLVSARLSKAGAPLVVLANRHAFIFNSSMCCWLRVADDTFPASNFVSAWPDADDGELANLQAGVAVAAGPSFLWNRMSLSEEKWQTRVHLEVQMSSALALKSASEYRRCLVAYARCLSKESDEARLRELCEELLGPVGSVGKLQLSKPDILGMSKRELLKGIVLPAMASNRAIQRLLNEFVDLVTECEAAEKALEPGGSIL
The following text describes a protein:
Function:
GTPase-activating protein (GAP) for RHO proteins. Required for polarized growth and maintenance of cell polarity.
Sequence:
MPLKWAARNKKPPSAPQSCASKPSSASQSSCVDERISATPRSSISSNSSPNSKNNMSRHSHSNGSVYSDETTLKTAQTHYTQQGQQAKPQQHTQQQQQQPQTPMQLQVPTGQAHKRTLTCEDMKAGARCEEQVSPCSQPAGSPVRRGGGLNGETYDGTVFRLGWVNKAQGAAPAREGRYSHQPTASLSSIGSERPHFTGGGTSGYQYVATAYRLHRAQLKGCILNLYKSGLTNVKYFDPALEPSAAALQMHQERQEMPLLQPPLPSEAVPAPSILEASMESGELRLEYLSEAYPHPDLQLDKKDGKILSGSLESLCHAVLFMPTTDAKRVTDILLLLPLLDDFTRVLNYFNLFGKVFSKHHPAGAAGADDLNQNYNISNETDRQLTLRLATVVQTVLDMFPGFLLDDKIFQSLVILLDTISFHDEDTSQELKVAIAEKQTVLVKLTGFANEPIQSAKLDVLIKVQSFLKLDTEKVANQIHKINLTFNRVWSPQADYSLLYDSQYTQKHVELNPLVFFNDKNVQYLSRLMVSHIFCEETGFTPKKRAEVLTKWVQLGCKFERLGDMVSWLAIATVICSIPVLRLTRTWQYVPDSYLKIIFKDWVPTIVQLDRRQMSSKSMNSVFILAPPNLNDAFVRDNVIPYFGDLVIHSDDLPRDSKYKYLEKKIRRTKNAFYKWQQRLDQAFAQDRDSASSFTDSLHLDEEEHDVADFYQYWRFHMNLPPMNIETIMEMSLKMEPPSINQQTYSKTYSTRSALISGAYLPTLFTTLLPSYSLFPQELLIAAASTPSTKNNNSSQASNRISQLSVNSTPHSNASSSSAASAVTGIDNIDVPITKEISSKLSNKQVLLKFIRDMFNVDINVFHISDDVIFKSIRDYEAKSRPTSVVIESPKRLSLLSSVSPDVSAVSSALENLDLFKNFNSSSDDIAEFTVQVVLKCASLEKIFDILVLTSRVFSNLVTTTDLVSYFNSEKARREKSGAQHNGQHSIGLLDFALISLIMDNELFAETFFNNYKSFTTTLCVLENLAKRFIGAKSSAISISLINKLRNSESSRQIPPSTTSNQFSASGIFKPSYDELKFPVWDLKVTSVEGCPLDYLAKIQIGVLESLYHLIREHYADFTDDLANNKTFLDILKIINQEVYDEWDKRLDDLRNNNNSSQKRKNSCDDNSSAKITFHVNDARPENSNENKRGAATNLGDSSLAALEKLQCTLQDLYVKIKSSYQRQLYRPLGVTRNCRKVHDMLCQFQPQTSMSALIMNGSSDTLDKMVTEFQALKHTDYDDIINWIYKLDHFITSKLKLVSNQDWIQVSQILESLSNDSLVALFNYPLHAESNNVIASGSSQLDDLQILDIFTWLSTLESGSAHIIDKFPASVQLIVRLHLSLTKFFTVHIAHLHSTYEARVNTCSLILEILNFVHVKNANVNLFHSDDAGEGSMATISPHVPSFIETAIENAIISPESRFFEVSWKQAYKTISEKDEKLTFIGSVLTGLDKSTAHFLDADNRQPVRPKNFSPCPGWFISRLLEITGLVPNMSIENSKMINFDKRRFINNIVINYQDLIPNTEQLPSHDDEKSAHQFGSILFHYGTESSIKAFRKASKEAASNEARKLKFQAMGLFNDILVTEVYKVQRDQKKQEQLTVQEHEAKRSVLIQHPNKVSVSSASSSVSGSSSGSTARTSNPAHAAYALNMAGSLSISAARHGRSSVSSRSSVISNTATATSPASGASPNQTSTSHHGGMGKKIGGFLRRPFSISGFTSSSSQYTTTSVVLSGVQANGSISPYELPELTSEIQDTKIVTVIKTFEIKSCIQINNYRQDPDMMHCFKIVMEDGTQHTLQCMDDADMHEWMKAITLSKRYSFHSKRFKGKTSNKIFGVPVEDVCEREGALIPNIIVKLLDEIELRGLDEVGLYRVPGSVGSINALKNAFDDEGAVHNTFTLEDDRWFEINTIAGCFKLYLRELPESLFTNEKVDEFVNIMTAYKNHEVDLSQFQNGIKTLLSTLPVFNYHILKRLFLHLNRVHQHVENNRMDASNLAIVFSMSFINQDDLASTMGPTLGLLQMLLQHLIRNPEHYFT
The following text describes a protein:
Function:
Acts a positive regulator of leaf senescence and may mediate auxin-induced leaf senescence. Plays a role in the regulation of seed germination by gibberellins and abscisic acid (ABA). Plays a role in the regulation of light-dependent hypocotyl elongation.
Sequence:
MRKIIGFRIGRRVSRWIFRKTRIQRSGYNRIHSTQQACMLMRPLAKLKSWGQRLKQSFRRRSTRRSAYIPVDHKKADPVPRGHLAIYVGQKDGDCHRVLVPIVYFNHPLFGELLREAEKEYGFCHEGGITIPCLYSDFERVKTRIASGSSSRVFPWGRHCRN
The following text describes a protein:
Function:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by taf1), facilitation of DNA opening and initiation of transcription (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MDLNNPPSKRFGDDDDIPANKRPKNEEYPEIPGYLGNRKPSYTQNPNSGPGKLHYASPRPNNVSSSVGVASGGDRQEADQLQDALISCGIQLKEEELNLSTSFYDPSSLNTFALTTEDRSRKSDFLNSFVLMQTVSNIVNLHRLKSMDSDIHALISMAVRDYLANLLQKMIVESHHRTSQLHTDNYKQVDNVRQTLANFAYKEYESEERRRTVLNIRRAEHEARLAELNSASTNEEGSSRRRKEQSSSAAAKNISEDAQNRMTNATASIMAGSALPSGGKKYSWMATDMTPMTPAVGGGFGIRKKDSNSLKPSSRDGVLPLQQEEKGIITIRDALAVLEMDREGAGRIFGRGAKAMMRAYIRLKD
The following text describes a protein:
Function:
Probable mitochondrial mRNA stabilization factor.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MTLLRAPQRFQYASRVFTSTSLSTPRHAYLTYSRVRSLTSTSHHPTKSHPSLSSSTSNTTSVEENDAPKSQCTPQASQHIPWYLQEESSVPAVSEVTLQEKLPELPENPPKILPELLEYIFKDLGLDELKLIDLRPLETPSALGANVIMIIGTARSVKHLNVSADRLCRWLRSEYKLSPYADGLLGRNELKIKLRRKNRRARIASRTGTMFDDKDDGITTGWICVNAGVVEEHPVEERVEGDFEGFGPLVGGTRVVVQVFTAEKRAEMDLETLWEGRLARAQRERQKHADAAKDDAPEEVRYPNSISPSPSDYKSPNVPRSWISLPHEQRRQFHIRSLRSFARPAHHAVFTPRFMSQNHTPAEHAIVGSELSSPTAMLLQYITTMPDQQLMSALGDRPDDESSTDFLRLFHHSLLGASPNVLALARLELLCLAHSRGHTGISKESVHRAFMGCCFSASHIPDRLIPTVVDILLTPRTGDNPDGEKWFTDADKELALSALDQLVLRGNDFMNLQFFTRLYYLSSLPPGPPGEENDDGLTPAERGAHVVRMIEILDIPFDPIHARTLMVYLFRNGDYDAFMKWWRTLPLKNSPRTREDYEMLFRLHADSGDSRLTRECISTWAPMMSREDPPIWLEGDLVAHLRDCLLLADERTPARAAEGTQSLFAKLWRACERELNKSEVV
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC); Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex. Nucleus membrane.
Sequence:
MTNKMNMSVETEKFINSFVKDVFVLPPTQDVAEDKHLIELSSMEQSTWSLLHILYNERLTNRYSRSSTSDEDGMDDVLICPNLSERSSEKDVSSLLFQHNTQLRQAQLILDWLEEKSRNIMKNDHNILEFSSDNMNAWENTLHTLKQQKSSYIPTKNIVTQLDPDSTSRQKKKLLELDDEDEKKLFKYIFSCIKSGMLDEACRMCHKVGHSWRSVTLQGWKLYHDDNISHLAPGGRISQVEGNLYRSLWRKTCQKMLQDVFVDEAVDRNIKYYKENKMIMTSMLGGESDADKLLTLEHIFSNIESCDNDIIKRQSQFRYHIIQKFIILGRVDVLIEYMSSWCLDKTSQAHPQLLKFMTHLTLFFRSYHARYRAEHETTIIKSYVEYLIGDNQSELIAKYTSYLPRDLQNVLYAKFLEGVIEVDKRQHSLQLASEFGLDLKSIIILVVNNICRREPFLEPLINTGFGGPGQLMETVTQADMKKIDCIGWLLFDEDWRLEAIKHSNFLFRVFICSRKIEACDILMKKLPIDSIQVIVNAFESPDVDKLPAHVDNAIREHICIKIYLEAQERFCEWFQWLHGKPSKPKGPGHMGSTLSEKMLHESNMKMYEEDLERWNKTLSSFAQKAVEKIKDVLTFVDGGWMVDQRQDDETVDEMRVQQIILLRQLCLPALFVLLQKIYHTMNMYKESMQLIDLLMSQQHQLYKVFSRGELEKYAYETLESS
The following text describes a protein:
Function:
The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization; Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
Subcellular Localization:
Cell membrane, sarcolemma. Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Nucleus, nucleoplasm. Postsynaptic cell membrane. Secreted, extracellular space.
Sequence:
RAVTRQFGLPDSTVAAGHLFNYTIPRDSFSGGKHRFEVAEAGERQLPRWMQFESPTLSGVPLVADIGQHYISVKAIAENPDDEVAEARDVFSVDVVEHQSSRSNPELPAASCPAGNPVAMATVTVDADANDLRPHERARLLTGLARFLEVAVAEASMAPMAPDEPAYDNSALMAGAGDSPSRLTAGLRLRWRVGCSSDVEPHHAAALKRLEASAEDGSLARLLGHPVVGWHVSSVQPAVRRARAHSHYIGGTPLVPAPLPTVVATETGNVIGERPMATPETRIVPTMASPIFDGPSVHHPHRHHHGEDHHARHIAASPTLSSVVLPTAALGMTPVLPPLRPTQTSFVDSAFGEVTPTFGPELVQPTSVGPEVSATPVLPTPETPRKPAGGNTKPTLNKRLPKLKATAGNKALGNLKVQKVSVEFLGVCPPVSSAPPPLHNKAPTKRNSIGQINATVGEILRYIIPDDTFYDFEDGTTRYLTLSFLSMDGLRLPESSWVQFNPRTQELYGLPFDGDVRRHEFQLVAQDSFGMSVEDVFVVLVQPRAQKKWAVEFSLHLDEDFEAFSRNISRKVLVAWKLARLYGDPDPRYVTVNTISAGSVVYAWTNNTLPYEPCPTETIRQLMSRLVHDNRTLTQRLVDEMKPEFRILKADTMPLGLCMDKGLPSTSVLHTVAPPPAAAPPEVGDASDVPPADDDIYITTIIPAVVIAVMLLLAALVACMLYRKKRKGKLSMQDSSTFINKGIPIIFADELEDKPDPAKPPVIMKEERPPLPPPEYPRGGSSSRGSTPQTGRRLPRDDAAPYQHPTPPFVSGRPDRQTRPKAAPTYRQPPPYVPP
The following text describes a protein:
Function:
Catalyzes the reversible conversion of the epoxide to 2-oxepin-2(3H)-ylideneacetyl-CoA (oxepin-CoA).
Sequence:
MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYREGVSAFLAKRSPQFTGK
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ferric enterobactin (Fe-Ent). Is responsible for the release of iron from ferric enterobactin.
Subcellular Localization:
Cytoplasm.
Sequence:
MPAAQPSGFVATLLSSPQAGEEAWWQQVARLGTPLVEAQDSGRVRMTFLWRDPDGDERYSAIRRVYADINGVTDHHSTDPQSLERLPGTDVWHWSMAIEHDWRGSYSLIPIVAAQLPPVFSDDGQLRDEQQREWWCSLFPCAIADPLNRDQSWGEQLSAAHMPAAPSQQAWRAVDNGTALPPDAARLTVLDWKSEQLDNQRRIWLYTTGISDEPAQRPLCIVLDGQKWAEETPLFAALEAETAAGHLPPAVWLFIDAIDGETRCRELPCDAAFWLAVQDELLPQAARLAPFSDDPDRTVVSGQSYGGLAALYAGLHWPQRFGRVLTQSGSFWWPNLQFITDFDQRDTLEPGVLVTEVRQGGQTAWPLVIFQEAGRREADIAFVNQQMHEALVAAGHQVHQRVYAGGHDTLCWRGGLIDGFRWLLTGDDPQAASRD
The following text describes a protein:
Function:
Acts in chromosome segregation and organization during mitosis.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle pole.
Sequence:
MESFATSDKLFESREFVKGLEELKKRREDGEMTCDLLWRMCRFCHELSTTMSGEQRRKMLIEGRDYGLEAMDLDPSSFLAAKWTAIMFGLVVDQLPTKEKINDGGRLKDMLDKALELDPTDFALLHLRARFSYTIANLSWLERKAASMLYSEVPKATIDDALVDFKAAYNQNADWIENLLFLSKCHLAKKEKQQAREMLNKAIVLPAASSNDAQFVTECKSLLQKC
The following text describes a protein:
Function:
Transcriptional repressor of genes that require a bHLH protein for their transcription. In the larval brain, required to maintain the self-renewal and identity of type II neuroblasts by regulating the expression of the transcriptional repressor erm together with other self-renewal transcriptional repressors such as klu and E(spl)mgamma-HLH. As part of its role in neuroblasts development, has been shown to be a direct target of the Notch signaling pathway, however might work also independently of N/Notch. In the developing larval and pupal brain, required for mushroom body differentiation. Involved in sex determination and SXL transcription repression when in complex with the corepressor protein Groucho.
Subcellular Localization:
Nucleus.
Domain:
Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG); The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho, a transcriptional corepressor recruited to specific target DNA by Hairy-related proteins.
Sequence:
MDYKNDINSDDDFDCSNGYSDSYGSNGRMSNPNGLSKAELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMTVKHLQSVQRQQLNMAIQSDPSVVQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSAHLNQCANSLEQIGSMSNFSNGYRGGLFPATAVTAAPTPLFPSLPQDLNNNSRTESSAPAIQMGGLQLIPSRLPSGEFALIMPNTGSAAPPPGPFAWPGSAAGVAAGTASAALASIANPTHLNDYTQSFRMSAFSKPVNTSVPANLPENLIHTLPGQTQLPVKNSTSPPLSPISSISSHCEESRAASPTVDVMSKHSFAGVFSTPPPTSAETSFNTSGSLNLSAGSHDSSGCSRPLAHLQQQQVSSTSGIAKRDREAEAESSDCSLDEPSSKKFLAGAIEKSSSAWRPW
The following text describes a protein:
Function:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. FOS has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Sequence:
MFRNFGSQGRGNPPYSGAVSGSSSISLGGVSTSTTQQEQKFTMAGSSHFVPSLNAITTNQDLQWMVQPSLMHPPGPSRSPVAPYPTMPAARAMGPQPSPSYLLRPGVIRAPTAHSSRRRNDEQLSQDELERRRIRRERNKMAAAKCRNRRRELTDSLQSETDQLEDEKSRLKKEIADLQKEKEKLELVLEAHRPICKIEESDSDSDPTPAASSLGAIKMEPVELSIPGPSKKPPVKMEKPKPKITLPTRPVASTSSTFATESESLHTPILISTPSLLSFSSNMVFTYPGGSSDASSSTTSHVTSHQQPGAREPCGIAHRRSSSSGDQSDHSLHSPSILTL
The following text describes a protein:
Function:
Protein-lysine N-methyltransferase. Monomethylates PRMT5, modulating its transcriptional activity. May also act as a histone methyltransferase. Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1.
Sequence:
MAYFQALFDRICGDLQRSTQEMSSDFLQLSTNQQRVSYALSIPSVHSYIKVKPMFKGKSAMEATKLREFGNKMFGQKDYDSALQMYSESVLKAPFDPNVNHPVAHGNMNGSSHGRAQCDKNDVTTNDGNEFSLALANRSAVLFSLGKYDLSMKDIDLALHHGYPKELTYKLHERKGRCLWNLGRDEEALQSFLTAKEHVTKSSLNSKKRKSWKATVDKQIAALQRTPSSVESADPSSTTNIPSVSYGTNSTFPSLSTAVEIRQSEQRGRHAVAAQDIRVGDVLIVEKPYGSVVLPEQGDTHCDYCCRRVSAPLPCQQCSTARYCSHECADLAWTQYHGVECQYLGLIHSSGVGGMGHLALRLVNRTGFHFLQEFERTLEDNISRKVNEPEKNAQDRNSGNTDYKDFPGLNDEGVYTNDYNSVYNLENHSLERKPSDLFRRTVMAIFLLRILQNGGVFLVPAQEVAEEDQLLVASHLLRHLQMIPCNAHEVSEFEFYRGDPDRCRYLEVASALHCTMLGMFNHSCDPVINRNFYGDVLVARAIRPVAKGEEITLNYSVLYTTQSRMERQYKLAGQYFFKCSCQPCAENWPLFYDMVQDLQTRNKLPKLKCRHCFSMLPGSEDKVINKMKCSVCGEEQELQALRTQLDSIVDEVFTKVGQVVTGEVESSLPALERCLERMEKIVARPYGYYDSCQEAIKQCYGIVGNCYERTTS
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
EIDMKDGATISGPGLPGIYSLKSFHFHWGTYHYKGSEHAIDGRKHDMELHIVHTKNNMTLEEAKKDPQGIAVLAFFIKKSNETPSVNTWKTLADLLEKIPEKGNSVNLDGQFSLGGLLKVADVRSYYRYFGSLTTPNCSQAVIWTVYPQPIEVTHKTLKKFTDSLYYTTKAEGRKMQKNYRPLQPLNNRKVYYFMENKHGHPCKEFRTNRNMSYV
The following text describes a protein:
Function:
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
Domain:
Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
Sequence:
MDSVTTEHKQEVDDRFDTARITAAVDALAEKHQGREDAFRTAMAQLLKAELIAARAAAQAILLKDRHGRRCAERLCHVQDEIIRILYSAATRHLYRSPIPSGAERMAVVATGGYGRGLMAPESDIDLLFILPYKQTAWGEQVAEAILYCLWDMGLKVGHATRSVDESIRQARGDMTIRTAILETRFLTGDQPLYDELVERFDKEVVQGTASEFVTAKLAEREERHRRGGQSRYLVEPNVKDGKGALRDLHTLFWIAKYVYRVRDTDELVERGVFDAQEYRTFRRCADFLWSVRCNLHFYSGRAEERLSFDLQREIAVRLGYTSHPGMQDVERFMKHYFLVAKEVGNLTAILCAKLEDQQAKPAPVLSRMMARLRPTPAKRRVPDSDDFIVDNNRINVAAPDVFKHDPVNLIRIFRLAQKHNLAFHPDAMRDVTRSLGLINAQLRENPEANRLFMEILTSDNAEIVLRRMNETGVLGHFIRAFGKIVSMMQFNMYHHYTVDEHLIRCVGFLQDIERGGIEEFAVASDLMRKIRPEHRSVIYIATLLHDVAKGRPEDHSIAGAKVARRLCPRLGFSPADTELVAWLIEEHLTMSTVAQSRDLSDRKTIENFAAVVQSVEQMKLLTILTTADIRGVGPGVWNGWKAQLLRSLYYETEPVLTGGFSEVDRGKRLTAAYAEFRNAFAEWPADELDAYIARHYPAYWLKVELPRKIRHARFVRSSEQAGHKLAINVGFDEVRGVTELTIFAADHPWLLSIIAGACASAGANIVDAQIYTTTDGRALDTISISREYDRDEDEGRRATRIGEMIEDVLEGKLRLPEVVARRTVRSKARPFVIEPEVTINNQWSDRYTVIEVSGLDRPGLLYELTTAISKLNLNIASAHVATFGERARDVFYVTDLLGAQINAPTRQSAIKSALTHVMAGDKAVQPAA
The following text describes a protein:
Function:
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
Sequence:
MSLDIAKYPTLALAENPEELRMLPKESLPKLCDELRQYLLTCVSRSSGHFASGLGVVELTVALHYVYNTPFDHLIWDVGHQAYPHKILTGRRDRISTIRQKDGLHPFPWRGESEYDVLSVGHSSTSISAGLGMAVAAEREGKGRRTVCVIGDGAITAGMAFEAMSHAGDIHSDMLVILNDNGMSISENVGGLNNHLAQLLSGKLYASLREGGKKAFSALPPIKDLLKRTEEHLKGMVVPSTLFEELGFNYIGPVDGHDVHTLTQTLKNMRDLKSPQLLHIMTKKGKGYAPAEKDPIGWHAVPKFDPASGTLPKSQSSLPTYSKIFGEWLCETAAKDSKLMAVTPAMREGSGMVRFSREYPQQYFDVAIAEQHAVTFAAGLAIGGYKPVVAIYSTFLQRAYDQLIHDVAIQNLPVLFAIDRGGLVGADGQTHQGAFDLSFMRCIPNMVIMAPSDENECRQMLYTGYHHNGPAAVRYPRGNGTSAVLEPLEMLPIGKGVLRREGEKIAILCFGTLLAQAQLAAENLNATLVDMRFVKPLDEELVLEMAAKHQVLVTVEENAIMGGAGSGVNELLMAKRRWVPVLNIGLPDLFVPQGEQDEMRSELGLDAAGIQRQIEAWLA
The following text describes a protein:
Function:
Required for Fe(2+) ion low affinity uptake.
Miscellaneous:
MISCELLANEOUS: Present with 573 molecules/cell in log phase SD medium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MGKIAEFLGNPGARPDVHHRAPTVDCKQYEEFGDSNDYKNDDVVRVVSHSDESTDDELCNVNLTETGAIFTSKGFTGLSKGFTDKTLDFLVRVAGSQAVFFIVWIILIIWVVIGIVYNAPFNWQVVMQDGQSIQSYVWDTLLMRQQLMSTHEQILICGRLKSRLASFKNYLTRSTPEEEKADCTVEANEVSSVENHIDPSAINGELPVENWYDRLSNVASRYMGSIAAMVIFWIGIFVWIGCGAIPKDAGNTPPYTGETTGSNPRLKKFSDAWQMYINTAVAVSLLICTTFLQNIRARHDYFTGRFLVDIFDMDEKIDYRIRKHFNDFETPHPVVTIESKKRSTGRKMIDWYADIIGTGIGVLIGVAVFATWIGIGSPMKWDDNWWLIIGTYTGLIGFLDGFVLREVYFRIVQHEEKNYSDVAKEDLELFQELGIECPEEFSGKAPEINTIGYRTSQYINRICSTPWSVLVSVIIIIGLICIASGLRWSTTGQLIANTPTMIIEEFFLLVLLQAHNWADRQRRVEVTALYARRRILLSYVEKRFPEVMMLEK
The following text describes a protein:
Function:
Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+).
Miscellaneous:
MISCELLANEOUS: Mrp-dependent antiport apparently occurs by a secondary, proton motive force-dependent mechanism, but the similarity of several Mrp proteins to membrane-embedded subunits of energy-coupled NADH dehydrogenase complexes raises the possibility that there is a capacity for electron transport that could provide a primary energy coupling option for Mrp functions.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQLLHLAILSPFLFAFIIPFLAKYAKRVHTGWFVLILPVLLFIYFLPMIRMTQSGETLRSVLEWIPSLGINFTVYIDGLGLLFALLITGIGSLVTLYSIFYLSKEKEQLGPFYVYLLMFMGAMLGVVLVDNVMVLYMFWELTSLSSFLLIGYWYKREKSRYGAAKSLLITVSGGLCMLGGFILLYLITDSFSIREMVHQVQLIAGHELFIPAMILILLGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGIYVIARFSPIFAFSAQWFWIVSLVGLFTMVWGSFHAVKQTDLKSILAFSTVSQLGMIISMLGVSAAALHYGHTEYYTVAAMAAIFHLINHATFKGSLFMAVGIIDHETGTRDIRKLGGLMAIMPITFTISLIGTFSMAGLPPFNGFLSKEMFFTSMLRVTHFDLFNVQTWGVLFPLFAWIGSVFTFIYSMKLLFKTFRGNYQPEQLEKQAHEAPVGMLVPPVILVALAVSLFFFPNILSYSLIEPAMNSIYPTLLDGHEKFHVHISQWHGVTTELLMTAGIVVIGTIGYLSLNKWKGIYKLFPSKLTLNRLYDKLLTMMEKGSYRVTKQYMTGFLRDYLLYIFAGFIILIGGAFAIKGGFSFKTEGMAKIGVYEIILTLVMISATVATVFARSRLTAIIALGVVGYTLALFFVIFRAPDLALTQLVIETISVALFLLCFYHLPKLRLKTKTRTFRMTNFIISLGVGVIVTLLGIASSSQRTKDSIASFFVKHSHDLGGGDNVVNVILVDFRGFDTMFEITVLTIAALGIYSMIKTKVKEEGKSGE
The following text describes a protein:
Function:
Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex. Can be partially replaced by GOT1.
Miscellaneous:
MISCELLANEOUS: Present with 279 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MSEEPPSDQVNSLRDSLNRWNQTRQQNSQGFNESAKTLFSSWADSLNTRAQDIYQTLPVSRQDLVQDQEPSWFQLSRTERMVLFVCFLLGATACFTLCTFLFPVLAAKPRKFGLLWTMGSLLFVLAFGVLMGPLAYLKHLTARERLPFSMFFFATCFMTIYFAAFSKNTVLTITCALLELVAVIYYAISYFPFGATGLRMLSSAGVNSARGVLRI
The following text describes a protein:
Function:
Involved in the digestion of the blood meal.
Subcellular Localization:
Secreted.
Sequence:
MKLPILLITLVAMVAAKSAPGRMAARYDHFRIYQLTIETNLQMEELKKIHEHISVHFLNELGAVGNKYNVIVGPLFHRALEKTLKFLEIVYEVIVDDLQKLIDESSVGDDSQMEWETYHTLDTIYDWIDQECAAHDFLECKVIGQSYEGRDIKSIRLSKRSGNKAIFLEGNIHAMEWISSATVTFLLNQLINSEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNGYRNESGDCYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFVSSFEDGYIRSYMAYHAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYGSTFTYGASGLLNYVVSGAAKDWAYGVKKIPFTCTVELRDKGTFGFFLPSNQITEVGLEVTAGLKALVNKAAEEGIFD
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MVSCSVAVSTYYNAEGSIMPSSTKFSLQFPSLPSGLPKDSENDALADSDCCVQCPQCHQTVQGIEALKEHIQLNHSGCPNGRRAKFPTDTSAPDDDDEDDVEDEDDERMAEEDEHHVDPEAVSPLPAPLDSLAASAVAGARATGDLVGSRLQAKCGSLLQLQQQKHQLAQLVDDREDEEEELEVAQGGSSPRDLLMAGLAPQTVPAADRSYGPRSMVISPAQDGSSNSSSGPSLPTGGTTAKEGGAELAVYECAQCPTTFASRDQLERHEMHHAPSADASCKVCNKPFANVYRLQRHMISHDESSQRRKFKCNECDKAFKFKHHLKEHKRIHSGEKPFVCPNCGKRFSHSGSYSSHMTSKKCINMGIRLNHNNNNNNNNNSSSHNNNNNNSTSHNNNSSNNSGSGSDSNHRSPQYPFHGGNGFTGIPNGHPGAIGAGGLGRSPIGLRPQAALHRDLDIAGRLRLVTSPSPTSSCSSATKHELDAIGPQPGGVDPLLLTKIQQASWLAVAMHNMQAMWDPNVLRLFDQFQQQPQSTSSSTDSETHEPMEDGLHQQQHQQQHQQQHQQGPPQPPPPPPATTSLLGDEDEQRPESARRPASSIDVVTMPEGVAQQNPSERMEIDEEEEEHEEDESCAEEKVEVVMGSSTAGSRQSPAAFHEEALQKITDNGSAVEEQNGEESSHQPQKSEYPEEQQSAESKLILPLLPKQEPLDEPAMESTNSMESQQHQQQQQQQQQQTQEQLTSSVSHDTLSVVKDEPSEETAIDPSLELSDEPKLNERDMERAHYSSPSAASSLSPSVSTALLHCIYCSEEFATEPEMLQHARMFCKRSLLLNPFMSASGALAQTGNGVPPGTIAGGGGISSSSSGNSSNSSCSDDDTDYDTVALKGDCGGAYGLHGGMAGGALGVGGAHGGPGGSGKVRVRTSISEEQQNELKKYYARNSKPSRDEFQAIAQHVKMEARVVQVWFQNNRSRERKMGVTGGSGGVGVGRQYAAGGGQAGGQTVAPAGTPNSPLHADRAPSVVTGQDATGDQPLDLSVKKGLLTVGEALLSAATNSQAAATALAAGSLPAVLLQADTMSALNEAINLSIKASCSPTAYFYHDIHPIHGVTAGPQAHAMLGLGTGLPRDTPSPQDGRGQHTAAPSLPSQPSPHAYGKYPPMHGLHPPHHPASLAGMDQLFRKFSPKLSAAVSTAATTGTMVGRASLSPGALDMMPDETGASYYGAFPDKKHLLQSMLNVPKRMGAGYGLGGGAGNGAATGAGGKDAGSLAHPAPDAEGQYVCDQCDKTFSKHSSLQRHKYEHSGQRPYKCMECPKAFKHKHHLTEHKRLHSGEKPFQCCKCLKRFSHSGSYSQHMNHRYSYCKPYREGK
The following text describes a protein:
Function:
Woronin sorting complex protein involved in both Woronin bodies (WB) formation and inherence. Localizes to large peroxisome membranes where it self-assembles into detergent-resistant oligomers that envelop hex-1 assemblies, producing asymmetrical nascent WBs. These structures are then delivered to the cell cortex, which permits partitioning of the nascent WB and WB inheritance.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein. Cell septum. Note=Localizes to nascent and mature Woronin bodies, fungal-specific organelles that plug the septal pore in case of physical damage.
Sequence:
MSVKEHHSTVGAIAEAVAEAAHGDLPGTKGHHPISAVIGTAITGGRQNAGTKGYLTAYLKQLETNPLRTKMLTAGTLAGSQELLASWLAKDRNKNGNYFTARVPKMATYGALVSAPLGHFLIWILQKMFQNRKSLRAKILQILVSNLIVAPIQNSVYLVAMAIIAGAKTWKQVQATVRVGFWKVMKVSWLSSPLCLAFAQKFLPEAAWMPFFNLVSFFIGTYINYITKKKRLAALRRKHFGDGAHGDHRHDRERERDRERERHSSPPHGHGPSHGGRPINPTLGSHHGGGPVPPPQDYPSLGQNPRY
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MEHFAPCAIRTKRFEVDQYVRVQLSNGRSEIGVVVSLDEVNDTAVIATRHGYDVTVRLDSVHRAFLLVLDLNGVLVARGRGSFADRPGVEEFVRFVMNNFVVAVWTSGLERTSIPIIDKVLNGYQDRLLFQLYRDSCGARPTPDKPYHTVKNLQRIFDSYPKSFNAVNTIIVDDSPDKCSHPDIALCPESFNDPERQANDRGLEMAMEVLKEVLRTDSHEPLIRAAQERLLAIAKRKEEAKEKQLNEGAKLSDVTDHMKGAAYNNANANTNGNGSGNGNDDDDNNNNNRNRNDDRSNSRKRSEGNNAKKDRSEHRSSDRREEPDTDAAAMKPSETFFWETRLCCENISVGCTRDACRFSHDPDDGKRPCSRKDKCRRGHANRWSTPVMGQKQKEKYQKVAVVRSSKSPQQATKAAGCTAVRGGGGMLDVLGLPEDVPLFSTHPDLQKGPDSRHPAVEPQLTASEELRQLIGLQSQQWKRPASGTVAQKPSGALHFKSDGGNGVSLLRQLQATVGAVSGGSEKVNRRKHRNR
The following text describes a protein:
Function:
Catalyzes the opening of the heme ring to form the open-chain tetrapyrrole biliverdin IX with the release of iron and carbon monoxide (CO). Produces specifically the biliverdin IX-alpha isomer. Plays a minor role in phytochrome assembly and photomorphogenesis.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MATTRLNPSCHFPASTRLSCESYLGLRTTGRISYARTLTAPRGYLAVKANGGQASVVTAAAITEKQQKKYPGESKGFVEEMRFVAMRLHTKDQAREGEKESRSPEEGPVAKWEPTVEGYLHFLVDSKLVYDTLEGIIDGSNFPTYAGFKNTGLERAESLRKDLEWFKEQGYEIPEPMAPGKTYSEYLKDLAENDPQAFICHFYNIYFAHSAGGQMIGTKVSKKILDNKELEFYKWDGQLSQLLQNVRQKLNKVAEWWTREEKSHCLEETEKSFKFSGEILRLILS