lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
Sequence:
MRNRREVSKLLSERVLLLDGAYGTEFMKYGYDDLPEELNIKAPDVVLKVHRSYIESGSDVILTNTFGATRMKLRKHGLEDKLDPIVRNAVRIARRAAGEKLVFGDIGPTGELPYPLGSTLFEEFYENFRETVEIMVEEGVDGIIFETFSDILELKAAVLAAREVSRDVFLIAHMTFDEKGRSLTGTDPANFAITFDELDIDALGINCSLGPEEILPIFQELSQYTDKFLVVEPNAGKPIVENGKTVYPLKPHDFAVHIDSYYELGVNIFGGCCGTTPEHVKLFRKVLGNRKPLQRKKKRIFAVSSPSKLVTFDHFVVIGERINPAGRKKLWAEMQKGNEEIVIKEAKTQVEKGAEVLDVNFGIESQIDVRYVEKIVQTLPYVSNVPLSLDIQNVDLTERALRAYPGRSLFNSAKVDEEELEMKINLLKKYGGTLIVLLMGKDVPKSFEERKEYFEKALKILERHDFSDRVIFDPGVLPLGAEGKPVEVLKTIEFISSKGFNTTVGLSNLSFGLPDRSYYNTAFLVLGISKGLSSAIMNPLDETLMKTLNATLVILEKKELPRAEVKEEKLVEIILSGNRSELEKLVEDFLKEKDPLSVIEEHLRPAMERIGELYDKGKIFLPQLILAAQTVKPVFDKLTSMLPSDSQGETFVIATVKGDVHDIGKNIVASVIRSSGYRVVDLGKDVDTSEIVEAVEKERPVALGLSAMMTTTVGRIKEVVEKLKEKNLKIPVIVGGASLNEKLAKELGADYYAKNASEAVKILKSLGR
The following text describes a protein:
Function:
May be involved in the peroxisomal activation of 2,4-dichlorophenoxybutyric acid (2,4-DB), a precursor of active auxins that inhibit root growth.
Subcellular Localization:
Peroxisome.
Sequence:
MWKSIGELSCDDYVKAGLTLEDAKEFDKLVSDVITKAIETDPRDQWKALVDESVLKPWHPHPLHQLLYYSVYSNWDSSVHGPPLYWFPSLSQSKSTNLGKLMEYHGPRLLGPSYKNPLESFELFRRFSVEHPEVYWSFVIDELSLVFHTPPRCILNKSKPEGTWLPDAVLNIAECCLMPSSHPKKEDDSVAVVWRNEGFDDSPVNRMTIKELREQVMLVANAISGSFEKGDTIAIDMPMTVDAVIIYLAIILAGCIVVSIADSFAAKEIATRLKISKAKGIFTQDYILRGGRRFPLYSRVVEAAPSKVIVLPASGTELHVQLREQDVSWMDFLSNAKPHSSGENYYRPIYLPVESVINILFSSGTTGEPKAIPWTQLSPIRSACDGWAHLDVQVGHTYCWPTNLGWVMGPTLMFSCFLTGATLALYSGSPLGRGFGKFVQDAGVTVLGTVPSLVKTWKRTNCMEGLNWTKIKFFATTGEASNVDDVLWLSSKADYKPVIECCGGTELASSYIIGSPLQPQAFGAFSTPSMTTRIIIFDENGVPYPDDQPCTGEVGLFPQHLGATDRLLNANHDEVYFKGMPMYKETRLRRHGDIVKRTVGGYYNVQGRADDTMNLGGIKTSSIEIERVCDQADECISETAAVTLTPPNGGPELLVIFAVLKEGFKQQSGEELKMKFSRTIQKDLNPLFKVSFVKIVPEFPRTASSKLLRRVLRDQIKQELLSLRSRI
The following text describes a protein:
Function:
Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol. Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MITISIVITIFILLSMSSILGILVFVVDTKWIPKIIIDLYSYGKSCEGKVFGSSIRTILIPKSWFTHFYVFGVFYTFLVLITMMWKIVLKNQLSKLVTSYISFVSPYTHNPLASTELSLLAAVLFFLQTSRRLYECLCVTVFADSKMNLGHYLVGYLHYWGCATVILSYSADYSRTNDFVWIPSSNDIPLQPIFGIILFTLAFYHQYIAHVSLANLRKDPKNKQKHSLPKNGLFNYVSCPNFLCEIIIYVSLYIILGFNHYPWALITFWVLTNQIMTATMTHNWYKSKFKEFPKTRRAIIPFIY
The following text describes a protein:
Function:
Controls stomatal patterning.
Subcellular Localization:
Secreted.
Sequence:
MAGVKFVVLSVLVFLLCSSVAHAAVEGGKEARRAGHFQVKQGSTPIDCTNQCDGCTPCNQVLDNVDPDHAVWKCQCGGSEARRAGHFQVKQGSTPIDCTNQCDGCTPCNQVLDNVDPDHAVWKCQCGGK
The following text describes a protein:
Function:
Probable ligand of isoforms a and b of the calcitonin receptor-like protein, pdfr-1, a G-protein coupled receptor. May not signal through isoform c of pdfr-1. Involved in locomotion; may play a role in circadian rhythms of locomotor activity. Modulator of egg-laying.
Sequence:
MSSRISVSLLLLAVVATMFFTANVVDATPRSQGNMMRYGNSLPAYAPHVLYRFYNSRQFAPINKRNNAEVVNHILKNFGALDRLGDVGK
The following text describes a protein:
Function:
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MGGWPRISPALYIAIGVLIGVVISLFFQPPAGGYGSVAELVVFPYSGKDGASEKLRAGRTSGDDHNHGGDAHSDEEVDDREAPDQAFEFHGNGSSHHHDDEDRLAREVAGKVRIFCWILTGKQNHENRAQHVKATWAKRCNQFVFMSSAEDPSLPSIDLQIPEGRDYLWAKTKASFTWLHKHHLEDFDWFLKADDDTYVIVENLRYMLLPHSPSEPIYFGCKFKPFTKQGYMSGGAGYILSRTALKKFVEEALPNKKLCSQNHGGAEDAEMGKCLEKVGVRAGDSRDADGHHRVGDSTDADGQYGSIEGKGFMPFVPEHHLSPGHIDPKFWFWQYTYYPMDQGPTCCSDYAVSFHYVNANLMYVLEYMIYHLRAFGVDRSLPVEVGHSQLEVAMESARANQGKDDVHFNVTAK
The following text describes a protein:
Function:
Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.
Subcellular Localization:
Cytoplasm.
Sequence:
MDLVGVTTPESRPGSAWGPNKCPWGTPQNTISCSLADVMSEQLAKELQLEDEAAAFPEVVAVAEGPFITGENIDTSSDLMLAQMLQMEFDREYDAQLRREEKKFNGDSKVSISFENYRMVHPYEDSDSSEDEVDWQDTRHDPYRAAKPVPTPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPGFQVGDGIGMDLKLPNQVFNALKQHAYSEERRSARVHEKKEHSTAEKAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSMEEGKEDNKVIPAECALKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLTRMQKAGISCPEVVMLKKHILVMSFIGKDQVPAPKLKEVKLSSEDMKEAYYQTLQMMQQLYNECNLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVSEAFSERDLFNAVSGLNITADNEADFLAEIEALEKMNEDHVQKNGRKAASFLKDDGGPPIICDE
The following text describes a protein:
Function:
May be involved in neurite outgrowth.
Sequence:
MGTVPDPLRSAKTSLIAASGEEEGLGEVQVASPQPRPEVLSENTNGLSSTPAEPDLSPRTAAKALMQASEHVPTQAAMSSPDIVSEVGKASPTLNSPGNTQLSGGREPTAPALCSAAGKDLIPATFTMPANQHIHPVVPGNQPHASPQSGPEDTLVKSQRTADGGQPEKSSCPVVVICGKDQMPCDFPSQETMQGIVQTEDTAARSFSPTSATVGGPEAERQQAVCTSQTRSCGSPTGEDGCSGNKPPSAATSDTQAMTSVIPQPSHLPSNGSMFPPDPEKVPLAAQPQVSRFKEASTMTSQAENEIKKTPPRAQQDAEVQAVASVQSRSASTSPSILAAFLKETPAPERFEQEQLRVICHGSANHTLELSENTLDPREAGQCRDLMPAVHIQTATAVSAAFQGENKSGSLPGEVLKTSAINVSSSDAQETCKQDGKSAGMTLAGQELTFRQLSGTTSTSLKASPSDQTSLSAGRQVETGHGLGKCETKPSEFAVATTSGHKPDPDCKLSDYCGPASRADQSRSLDLTNQGDAREKKLASPQIMKEQESPGIDILEVRARAEAKSLLLNPKSQESGGVASGASPTPSPVRRSQEGTGEENRQTKTAASLSLPSDAIGDSSPGSGKRTPSRSVKASPRRASRVSEFLKEQKLNVTAAAAQVGLTPGEKKKQLSADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDPESLGIAIQNHLQRQIREHEKLIKAQSGQSRRSISSDTSSNKKLKGRQHSVFQSMLQNFRRPTCCIRPAPSSVLD
The following text describes a protein:
Function:
Deformylase that catalyzes the conversion of N-formylmaleamic acid to maleamate in the aerobic nicotinate degradation pathway.
Domain:
Shares some sequence similarities with the AB hydrolase superfamily.
Sequence:
MSTFVAGGNVSANGIRQHYLRYGGKGHALILVPGITSPAITWGFVAERLGHYFDTYVLDVRGRGLSSSGPDLDYGTDACAADIPAFAAALGLDSYHLLGHSMGARFAIRAAAQGAPGLQRLVLVDPPVSGPGRRAYPSKLPWYVDSIRQATVGMSGDDMRAFCATWSDEQLALRAEWLHTCYEPAIVRAFDDFHEVDIHQYLPAVRQPALLMVAGRGGVIEPRDIAEMRELKPDIQVAYVDNAGHMIPWDDLDGFFAAFGDFLDHPLV
The following text describes a protein:
Function:
Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA.
Subcellular Localization:
Nucleus.
Sequence:
MASKRKSTTPCMIPVKTVVLQDASAEAQPSEALHEGPQQDLPSEAPATSSEAAQNSSSTDGTALANGHRSTLDGYSYSCKYCDFRSQDITQFMGHMNSEHTDFNKDPTFICTECSFLAKTPEGLSLHNAKCHSGEASFGWNVAKLDNHVVVEQSVPESTSTPDLLAEPNAEGTDGQAEIIITKTPIMKIMKGKPEAKKIHTLKENVPSQPVGEALPNPLAGETEVKEGDHSFVNGAVPVSQASTNSAKTPHVANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHAHQPLPTSKSLPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVANAGNVQHLIQAALPGHVVGQPEGTAGGLLVTQPLMANGLQAPSSSLPVAVTSIPKQPTVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRNLKGSRAMMAGDHGSILIDSVPEVPFSPSSKAPEVTCIPTAATLATYPSAKRQSWHQTPDFTPTKYKERAPEQLRALESSFAQNPLPLDEELDRLRTETKMTRREIDSWFSERRKKANAEETKKTDESASQGEEEAAEGEGGEEDLASDLRVLGENGSPETPGNHTLAERKVSPIKINLKNLRVTEANGKSELPGLGTCEPEDDGLSKLAEQPPGRVSYKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPGNRELLQDYYMTHKMLYEEDLQSLCDKTQMSSQQVKQWFAEKMGEETRAVADTGSEDQGPGDPAAVHKGMGETYSEVSENSESWEPSAPEASSEPFDTPSPQAGLQLAFTAGIQAPGCKTRKGATAAHFQRTQFTAFCEAHSTRCSQRGWDTTRGDCLR
The following text describes a protein:
Function:
Seed storage protein.
Subcellular Localization:
Protein storage vacuole.
Sequence:
MHKLLFSLLSVVSLSFLLFFHGAEARQREAPFPNACHFSQINSLAPAQATKFEAGQMEVWDHMSPELRCAGVTVARITLQPNSIFLPAFFSPPALAYVVQGEGVMGTIASGCPETFAEVEGSSGRGGGGDPGRRFEDMHQKLENFRRGDVFASLAGVSQWWYNRGDSDAVIVIVLDVTNRENQLDQVPRMFQLAGSRTQEEEQPLTWPSGNNAFSGFDPNIIAEAFKINIETAKQLQNQKDNRGNIIRANGPLHFVIPPPREWQQDGIANGIEETYCTAKIHENIDDPERSDHFSTRAGRISTLNSLNLPVLRLVRLNALRGYLYSGGMVLPQWTANAHTVLYVTGGQAKIQVVDDNGQSVFNEQVGQGQIIVIPQGFAVSKTAGETGFEWISFKTNDNAYINTLSGQTSYLRAVPVDVIKASYGVNEEEAKRIKFSQQETMLSMTPSSSS
The following text describes a protein:
Function:
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
Sequence:
MSKKVVLTREASKNKPWQTYFSQNGYEVMSIPLIKTQPIKINLTREQQETDWLFLTSANAVEYFFTNQYERSNYKIAVIGEKTKEKLAEFGHEPSFVPSIYQSEVFLEEWLNENPEKTSILLPQSNLSRTIIKDTLIEKGYIVFSIELYETIFPEASKKLLTEQLKLNETQIIVFASPSAWKNFYSIAKSFPAQKEKWHIASIGSITTEAILADGWEVKYQPKTFTMKHLADLIIQEELK
The following text describes a protein:
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. A subunit of the levamisole-insensitive nicotinic receptor (By similarity).
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=The cam-1 protein is required for correct localization.
Sequence:
MSSVCALLLSCALFLVAHGSLQERRLYEDLMRNYNNLERPVANHSEPVTVHLKVALQQIIDVDEKNQVVYVNAWLDYTWKDYNLVWDQAEYGNITDVRFPAGKIWKPDVLLYNSVDTNFDSTYQTNMIVYSSGLVHWVPPGIFKISCKIDIQWFPFDEQKCFFKFGSWTYDGYKLDLQPATGGFDISEYLPNGEWALPLTTVERNEKFYDCCPEPYPDVHFYLHMRRRTLYYGFNLIMPCILTTLMTLLGFTLPPDAGEKITLQITVLLSICFFLSIVSEMSPPTSEAVPLLGIFFTCCMIVVTASTVFTVYVLNLHYRTPETHDMGPWTRNLLLYWIPWILRMKRPGHNLTYASLPSLFASKPNRHSESLIRNIKDNEHSLSRANSFDADCRLNQYIMTQSVSNGLTSMGSIPSTMISSTNGALTDVSQQATLLILHRIYHELKIVTKRMIEGDKEEQASNNWKFAAMVVDRLCLYVFTIFIIASTIGIFWSAPYLVA
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEPSPMSPSGATLPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRSSAATTTVTAVAAPSVSVPCASVPSGSGGTVAPATVGSVRSHTSSRASENQSPSSSNYFSPRESTDFSSSSQDAFVASAVGSGNRRDGGPVFPVPVVGSAGTTSGKLLLEADELCDDGGDGRGAAAPGAGLRRPNCLPASAVPQKHWVYVKRARNCPAPASLVHQDPDLEDEEEEEDLVLTCEDDEDEDLGNGSGVPAGGEPEATLSISDVRTLTEPAEKGEEQVNFCESSNDFGPYEGGGAGAGLDDPGGPTPSSYGLTHPPRPLLPLDVPGNQILVFPSSSSQAPGQPPGNTAEHGAVTLGGASAVGLGIPSGSGGTPGGAGNSDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECSVCAKKFMWRDSFMRHRGHCERRHRMGAGGAASVPGPGPGAPTGPALQPKRESSAVGGGSGDEANSATPPSNRRVWSPPSVHKVEMDFSGGGGAAH
The following text describes a protein:
Function:
Interferon-induced ISG15-specific protease that plays a crucial role for maintaining a proper balance of ISG15-conjugated proteins in cells. Regulates protein ISGylation by efficiently cleaving ISG15 conjugates linked via isopeptide bonds. Regulates T-cell activation and T-helper 17 (Th17) cell differentiation by deubiquitinating TAK1, likely to keep TAK1-TAB complexes in steady conditions. In turn, restricts activation of NF-kappa-B, NFAT, and JNK as well as expression of IL2 in T-cells after TCR activation. Acts as a molecular adapter with USP20 to promote innate antiviral response through deubiquitinating STING1. Involved also in the negative regulation of the inflammatory response triggered by type I interferon. Upon recruitment by STAT2 to the type I interferon receptor subunit IFNAR2 interferes with the assembly of the ternary interferon-IFNAR1-IFNAR2 complex and acts as a negative regulator of the type I interferon signaling pathway.
Sequence:
MGKVFGLKRQTCKSVLAESPQSPADLVEKKEEDSNMKRKTEQPREHPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNMDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKYNVPMFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYMIRVKDSLICLDCAMESSRNSSMLTLPLSLFDVNSKPLKTLEDALHCFFQPRELSSKSKCFCKNCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHALHFPESLDFSQVLPMEREPCDAEEQPGGQYELFAVIAHVGVADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKMEC
The following text describes a protein:
Function:
Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
Sequence:
MPSSFANESQFRYQSSRNRASCTSRSPSEPESPAPVTPNCDVVDQALAELQLQSQDIRKQQDLVDTTATSSSSRKRSGWEIKGSKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGDPTTFGNLKAADETMKAVLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDGEIDANEVVLCSGCSSALEYCILALADRGQNVLVPRPGFCLYYTLAQGLDIEVRYYDLLPDQQWRADLVQLESLIDENTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVFPGSKHLAVSSLTTEVPVLSCGGLTKRFLVPGWRMGWIIVHDRKNRLRDAIVGLKNMCGRILGSNTIIQGALPDILTKTPQSYFDGVIDVLHSNAMLAYKMLKQVRGLDPVMPNGAMYMMIGVSIERFPEFKDDTHFVQEMVNEQSVFCLPGSCFEYPGYVRIVLTVPGAMIEEACSRIAEFCDRHYKKESRNFIEHGLLDCDDVAF
The following text describes a protein:
Function:
Transcription factor that acts as a regulator of iron homeostasis. May act as negative regulator of iron transportation from root to shoot. Does not seem to be involved in the suppression of the induction of iron deficiency responsive genes.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing BHLH133 are hypersensitive to iron deficiency.
Subcellular Localization:
Nucleus.
Sequence:
MECSSFEAICNESEMIAHLQSLFWSSSDADPCFGSSSFSLISSEGYDTMTTEFVNSSTNVCFDYQDDSFVSAEETTIGNKRKVQMDTENELMTNRSKEVRTKMSVSKACKHSVSAESSQSYYAKNRRQRINERLRILQELIPNGTKVDISTMLEEAIQYVKFLHLQIKLLSSDEMWMYAPLAFDSGNNRLYQNSLSQE
The following text describes a protein:
Function:
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MFRPFVFCLHLAVLFILYLGFQNVFLDVEKNDCQMTYMFQEPLYIKVKLDASLKLNYPNYNLYYYNEGSSHISLNGVPALFIPGNAGSYRQVRSLGSVALRMAENIPKKNKIDFFAIDFNEELSGFFGGFLEKQSEFAFLCVDHILSIYNRTKNNKQSSMFIVGHSMGGLVGRALFKYGINDDKVPVIITQASPHQMPVLLVDEEMKRFHQSLYYPTTTENMPNVTLVSTGGGSRDFLVRMAATRPGKLFGNIISTSVSAALVAVFTFSIFNYFSGVGFLEREINTVSMPKAWVSTDHLCHVWCKQVVMATVRAMYDCVDESTKQITKSPPLRHEVLKYHFVENRGPKHYTTSFPSNFKLNKLSIEWKEVNMPWKFYGSVEKSMHAAFNVKTLVYDGKIIAVSNLEFVDWVGACSVNCDEMISFKSKTMLLPSEKGQFLKVVQLDYNDLRTFDWLVITIPASNQNDIQIAVEHMNPRQRTLTKVVPFLLKPFTKHFSQLADGNNNNNEDIVITETTFSKNSIYHKLNMKGFYDVLQAFHVSIEPVNCGATTQGHSVLKFQSPWSNDPTYTVLRDKLTEVNIMLSSNEPHMDSTNRRSIKQTTQQHQQQQHSPPYLELYIASSCSYRMKVTLSKSSMAGQFVRFYMHYIPSFLVVQVFLVFGRQLKTFQSVMLDVNVCLFTWYHPFSVIPLVAAGRYLLRLISQLLVYMDFCIFTFYVHTDDDDITILKRNDIWNSAVLVILYFVSMILVSLLSYICQFALYLCAKVMNPVCRRLYSNKLGVFLKCLTLTCAALSSWFVCGACGLLFVLIVHLARVFSMYLDTPSVKSFQTIMYYQSNIRQFYLTTFLLFFFQFVVNAPSLVVYIKDKNVYSMHDDPSFCHAVVAIVTSIVLTSSSYPLKYRLHSKAVSYVIHLTALFTVLYATVTLYRLPYFIDLILIILLLHCILSSIFSSSDSSSSRIEDVPLPDGGLKEFKFCKKK
The following text describes a protein:
Function:
Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome, attB, and a site in the circular form of ICEBs1, attICEBs1.
Sequence:
MSVKKLENGQYQVDVSFGFDPITGERIRTRPVASTRKEALELEAKLRREFQEERARKSRSVSFPTLISIYLASCEIDSKPNYYQNQKYIINKHISDYFLKSDIQKITHREITDFRKHLMETGLSNKSVNNIMTSLSKIFDTAVHEEILKRNPCDNVKRLPLTRKKMKFWRPEEFKKFISLIPQDQLLFKTFYTVAFLTGLRCGEMLALQWKDIDKILLEIDVHKSCTWLDGQFVVTTPKTKNSIRRVSINKKLLKLLERWKEAQEELFNELGIRHSHDTYIFQYKDTPSRKDIFSRKIKYFCKDSDLTPIRLHDFRHSHVALLIHQGEDYITIKERLGHGSVKTTIDVYGHLYPNKQKEMADKLDDLL
The following text describes a protein:
Function:
Catalyzes the specific phosphorylation of arginine residues in proteins.
Sequence:
MKEATDLSVLVKNSGEWLRGTGPESDIVISSRIRLARNLAGFPFIRKCSPEDREKIERQVRSRLENLPDWDEIPYVDIATLSEVDRQFLVERQLISREIADSEGSRAVAIDPSEQYSVMINEEDHLRIQVMHSGLDLVSAWEQIDRIDDAIEGEVLYAFHNKFGYLTACPTNVGTGLRVSVMLHLPGLVITQQIEKVFRSMQRINVTVRGLYGEGSQYTGDFYQVSNQVTLGHTEKELLEMVGQEVVPRIIDYERKAREFLIDKGQQDLHDDVSRALGILSTARKISSEETMHYLSKVRMGVNLGLIDDVQLATINKLFIHTQPAHLQKLHGRVLTTSDRNVQRASYLQRHLCGPADRADELN
The following text describes a protein:
Function:
Cell wall formation.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTPHLDSAQDIDLSRVHLIGIGGAGMSGVARILLARGKTVTGSDAKDSRTLLPLRAVGATIAVGHAAENLELSGELPTVVVTSFAAIPQDNPELVRAREEGIPVIRRSDLLGELLEGSTQVLIAGTHGKTSTTSMSVVAMQAAGMDPSFAIGGQLNKAGTNAHHGTGEVFIAEADESDASLLRYKPNVAVVTNVEPDHLDFFKTPEAYFQVFDDFAGRITPNGKLVVCLNDPHAAELGERSVRKGIKTVGYGTADAVQAHPEVPAMATIVDSQVVAEGTRATINIDGQEVSVILQIPGDHMVLNGAAALLAGYLVGGDVDKLVEGLSDFSGVRRRFEFHGAIEGGKFNGAAIYDDYAHHPTEVTAVLSAARTRVKAAGKGRVIVAFQPHLYSRTIEFQKEFAEALSLADAAVVLEIYGAREQPVDGVSSEIITDAMTIPVVYEPNFSAVPERIAEIAGPNDIVLTMGAGSVTMLAPEILDQLQNN
The following text describes a protein:
Function:
Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.
Subcellular Localization:
Nucleus.
Sequence:
MANTKRVVYVGGLSEEVDEKVLHAAMIPFGDIIDVQIPLDYETGKHRGFAFVEFELPEDAAAAIDNLNDSELYGKTLRVNIAKPMKLKEGSARAVWTDDQWLREHSGKAKKNDGDDDNDDVGGADDDDHNKEGGGGDNNAKNSTSTDCTTPTTTTTTTTSAKKSVANPQVYMDVKIGNKNAGRIVIVLRSDVVPKTAENFRCLCTHERGYGFKGSSFHRVIPQFMCQGGDMTNNDGTGGKSIYGRKFEDENFTLKHMGFGTLSMANSGPNTNGSQFFICTEKTDWLDGKHVVFGKVIAGQDVVRKMEACGSASGKTKEKIVISDCGEFI
The following text describes a protein:
Function:
Very low affinity permease for methionine.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQAIKAETARFMEVPQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFGVTDDSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHKNEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLNRVGFLPPYQIMSLLVIVACFFFWLVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC
The following text describes a protein:
Function:
Ligand for the sex peptide receptor (SPR). Stabilizes sleep and maintains sleep homeostasis to inhibit the activity of wake-promoting circuits, such as those that involve the pigment dispersing factor (pdf) neurons. Regulated by the circadian clock network and pathways associated with a sleep homeostat. May also have a regulatory role in gut motility.
Miscellaneous:
MISCELLANEOUS: All five Drostatin-B peptides activate SPR with comparable efficiency, however Drostatin-B4 is a slightly more potent ligand.
Subcellular Localization:
Secreted.
Sequence:
MAHTKTRRTYGFLMVLLILGSACGNLVASGSAGSPPSNEPGGGGLSEQVVLDQLSESDLYGNNKRAWQSLQSSWGKRSSSGDVSDPDIYMTGHFVPLVITDGTNTIDWDTFERLASGQSAQQQQQQPLQQQSQSGEDFDDLAGEPDVEKRAWKSMNVAWGKRRQAQGWNKFRGAWGKREPTWNNLKGMWGKRDQWQKLHGGWGKRSQLPSN
The following text describes a protein:
Function:
Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation.
Subcellular Localization:
Secreted. Note=Secretion enhanced by O-fucosylation of TSP type-1 repeats.
Domain:
The pro-domain is not required for folding or secretion and does not perform the common function of maintening enzyme latency; The globular cysteineless spacer domain adopts a jelly-roll topology, and is necessary to recognize and cleave vWF. The C-terminal TSP type-1 and CUB domains may modulate this interaction.
Sequence:
MHQRHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRPPSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSLGAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGSGCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQPGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRRYGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSLVPHEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLEPTGTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDMTFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWESESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
The following text describes a protein:
Function:
Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acids (By similarity). Plays a role in the early migration of AQR and PQR neurons, which descend from the Q neuroblasts.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein. Secreted, extracellular space, extracellular matrix, basement membrane.
Sequence:
MKCLRWRSNRHRIYLLVACGALFLLNRHLTQEESRIDEEDEELTQVDVNEDDKKIECEPPGSIESKCIADNGKSMKCWKDEEDVYFPVSYLKKRFDMTGKLGKDGSTFELYTSYAKMRSPDSTYDPLGPFGHFSTYSVETRDRVRCVSAKTDVPMSTQWDPIPYYYPIQISQYGLQHYSRMKLDSISNKSEASPKDDVILGVNSKEWKGAAGMHETTERLFFNDEQMGKVVNISAGAALANAGAYVYLDKSPDLHVISFDWKPYEANSSFTVLAKMKQDDLLVLINYVYSEGNGKCVWQEEERISDDYIVQKPKKDGQVSYSYSYIGNSPIGEWSTVTRDLLVDVARALSSGDNRKKDDNVVLHAGDLRLVSLGFRGELTVKQKITQRREQHSHAFYAAADWLVKNQNDRGGWSVPVERSIAERKLVLPPGWHSAMAQGHGISVLTRAFKHFNDEKYLKSAAKALKLFKINSSDGGVRGEFFGNIWYEEYPTTPGSFVLNGFLYSLIGLYDLSQLELMIDENDETMRAKIQEAQELYSAGVRSLKQLLPLYDTGSGTIYDLRHVALGTAPNLARWDYHAVHVYLLKWIAGIEKDEVLSKTADRWIGYAYGKRAKHN
The following text describes a protein:
Function:
RNA-binding protein that acts as a pre-mRNA splicing factor. Acts by promoting exon inclusion via regulation of exon cassette splicing. Also acts as a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity.
Subcellular Localization:
Nucleus.
Sequence:
MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHDRKRSRSKERKRSRDRERKKSRSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQNEVLAAAASVQPLATQCFQLSNMFNPQTEEEAGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHSLFPDSMTATQLLVPVRR
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDTKQVAEKILNLTLETIFFLTGEDYIVVKKQKEPNKESVGTCISEGICPVRNPIPTPRQIHDGNILALTHTIVHLLTGEVLNRCKDVSFGFSAEDQLYQMENQQSPSPLGRDTLNPEITRNETIPECEMDCEDPPERGMDPGPPAGGSSNTNSPLSPGDLYAQESLGEENKMTQEYKVKQEEGTFPQQCDYEQIPTEISTGQHSLNLELLEKEYEGKCMNPAGDKMQPALLTGECSNKNSPLATPRDLYVQESLQEENRMTQEYQVKQEDVNFRQQCNDEQIPTQIITGGAASWRIPRGELHSISEFPNTNDQSASVPCENSPAERTSQSVRLSNNNFSFHEEVGLHEPPRHQTGTEYSSLLFNVPGVDYVQNHSESRGRSREKPYVCSKCGKGFAHKSTLVKHQSFHMGDFTCSQCGKSFNWKSNLLVHERSHAGQKPFACSECGKCFAHKSTLVKHQLFHMGAFTCSECGKGFSQKSNLLAHQRRHTGHKPFSCFECGRCFSQNSSLITHQRIHTGEKPFACSECGKCYTQYASLLVHHRTHTGEKPYVCSECGKAFNQMAHLVKHQRSHKP
The following text describes a protein:
Function:
Plastidial enzyme of the prokaryotic glycerol-3-phosphate pathway that converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at position sn-2. Utilizes palmitoyl-ACP (16:0-ACP) to produce phosphatidic acid containing a saturated group at position sn-2, which is characteristic of lipids synthesized by the prokaryotic pathway. In vitro, can use 16:0-CoA as acyl donor.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein.
Domain:
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
Sequence:
MDVASAPGVSSHPPYYSKPICSSQSSLIRIPINKGCCFARSSNLITSLHAASRGVTRRTSGVQWCYRSIRFDPFKVNDKNSRTVTVRSDLSGAATPESTYPEPEIKLSSRLRGICFCLVAGVSAIVLIVLMITGHPFVLLFDRYRRKFHHFIAKLWASISIYPFYKTDIQGLENLPSSDTPCVYVSNHQSFLDIYTLLSLGQSYKFISKTGIFVIPVIGWAMSMMGVVPLKRMDPRSQVDCLKRCMELVKKGASVFFFPEGTRSKDGRLGPFKKGAFTIAAKTGVPVVPITLMGTGKIMPTGSEGILNHGDVRVIIHKPIYGSKADLLCDEARNKIAESMNLVS