lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.
Sequence:
MAENKTEFQCNGVVGGNFEAVRKKGIEFDPPLYKQRYFFVKDLVNQHKTKKVADLGCGDNTLLWILKIHSCAELLVGVDINDSVLHYSRNKLSPSWGDQLSPRDLDLTVTLYIGSAVERDSRLRGFDLITCIELIEHLNSEDLARFPEVVFGYFSPSMIVISTPNSEFNPLFPSGNALRDLDHKFEWNRMQFQTWALDVANRYNYSVEFTGVGEPPAGAENVGYCTQIGIFRKNEAKATELCISEQDDEHVYELFYTELYPSLQQEKVRKFVVLNEVYRQVYLMRRRFIKILDPLAASIFNSADCDPAKVEERRLLGPPMFTDARLAEIRLLGPPFTEAEKTEFILLGPAFTEAEKTKIVNSPKPFCVGNEFCVPLERLLAYPKVNRICDSIDTLKMYIADTVTLSSDGSAMKVDIPDHDDY
The following text describes a protein:
Function:
Catalyzes the deamination of many pterin metabolites, such as formylpterin, pterin-6-carboxylate, pterin-7-carboxylate, pterin, hydroxymethylpterin, biopterin, D-(+)-neopterin, isoxanthopterin, sepiapterin, folate, xanthopterin, and 7,8-dihydrohydroxymethylpterin. May be involved in a degradative pathway for catabolizing pterin rings.
Sequence:
MSYSFMSPPNAARFVLSNATVPAVTVVGFTGPSSEGLMKADIVVADGLIKDILPAGTAPAELAKADMRDGMVWPTFADMHTHLDKGHIWERRANPDGSFMGALDAVRSDREANWSAADVRKRMEFSLRAAYAHGTSLIRTHLDSLAPQHRISFEVFSEVREAWKDKIALQAVALFPLDFMVDDAFFADLTTVVREAGGLLGGVTQMNPDIDAQLDKLIRAAAANGLDIDLHVDETEDREVLTLKAIAAAVLRNGFTGKVTAGHCCSLARQDENVAAATIDLVAKAGISIVALPMCNMYLQDRHPGRTPRWRGVTLLHELAAAGVPTAVASDNTRDPFYAYGDLDPVEVFREAVRILHLDHPLDTAARVVTTSPASILGRPDIGRIAVGGPADLVLFSARRWSEFLSRPQSDRVVLRKGKVIDRSLPDYRELDTVIGA
The following text describes a protein:
Function:
May be involved in pre-mRNA splicing.
Sequence:
MSGSGTSSSMSAPVVPSGSFPSALPPYGIPPPGFIPPTPGIPPPFGVAMPSMAPPSVFGVPPFGASAVPPSGFFPQTMPAQGSIENENKRTWTEHKSPDGRTYYYNNLTKQSLWDKPDELKTAAEIMLSQCPWKEYKTEDGKIYYHNVSTKESSWTIPPELGELKSKIATEESNKTTIANGQTGTDILSSTVQISTAAMTVSQSVVTDSLPTPTRAPISALDQAMAATLAAITVPSPQTEDSMDAKPSPSSDSRTSTPEPKTTFKDKREALEAFKELLREKNVPSNASWDQALKYIQRDPRLAALGKLTERKQAFHAYKTQKQKEEKEEQRLKAKKAKEDLEAFLLVDSSISSTTKYFRCEEIYGNLEVWKNVPEGERRDIYEDAIFHLSKREKEEEKALRKRNMKNLTRVLDSITDITHRTAWTEAQQLLLDNPSFAEDNDLLAMDKEDALVVFEQHIRELEHEEEEERERGKRRIKRLQRKNRDSFLNLLDELHENGKLTSMSLWVELYPIISTDLRFSAMLGQPGSNPLDLFKFYIEDLKSRFHDEKKIIKEILKQKSFEVDIKTTFEDFATVVCEDKRSVILDGGNVKLTYNALLEKAEVREKERLKEENRRSKKLESAFRNLLRAKELDHLVSWEDSVSKLEGDPAFDAITEESDRIRIFKEYQRDMEETCGHHHSRSKKNKKKEKKQKRRSSSSRSPSTTRSGSRSKSRSKSPSRSKSDENEAKLVDEELPSTHKKSKKKKSKKKKERSRSPSSDSEENRTKEKKKDKEKKSRNDSGNDKKNKEDGEWSEDELERRRRLLLEQLAEEHQ
The following text describes a protein:
Function:
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MVRSFPNIVITGTPGTGKSTHSSLLASSYSPSGSSCHPLRQIDVGVLVKKEGFYTEYLEEWQSYEVNEDQLLDHLEPLTGTKAPEPLDAEEFDQAELTQAKQQGDEGEERGGLVLDWHTCDVWPERWVDLVVVLRCDHGVLWQRLEKRGYPLKKIQENNEAEIMGVVADDARSSYPAEAIVELQSQESGDVEENVERIIQWIHAWRQARGLE
The following text describes a protein:
Function:
Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Sequence:
MDRLADKLEQGKLYLRRPIHQVLPPSLLLHLVPPLPPLRYILVGLAALLLLLLRVWLILPGTSHRRAAQKPTTHRSYTVAAFLGSGGHTTELLQLVSALPTQRYARRIYLVSSGDRFSWKKANDLERTLSADRTSSAHVLQIPRARNVHQSFVTTPWTLAKSIAFCLHHVALRPLTRPCNKSNRVLADVILMNGPGTCVPIVIAVYLLRVLALPSPKLIYVESFARVKSLSLTAKLIRPFVDRFVLQWPRHASDLTPAVKAKATPNTVYSGWLV
The following text describes a protein:
Function:
Catalyzes cleavage of the C(2)-C(3) bond in oxaloacetate and in (2R)-alkyl malate derivatives to form oxalate and acetate, and alkyl carboxylates and R-ketocarboxylates, respectively.
Sequence:
MAPPNGTTNGETEVATQGSYTAVSTGRKTTMHRLIEEHGSVLMPGVQDALSAAVVEKTGFHAAFVSGYSVSAAMLGLPDFGLLTTTEVVEATRRITAAAPNLCVVVDGDTGGGGPLNVQRFIRELISAGAKGVFLEDQVWPKKCGHMRGKAVVPAEEHALKIAAAREAIGDSDFFLVARTDARAPHGLEEGIRRANLYKEAGADATFVEAPANVDELKEVSAKTKGLRIANMIEGGKTPLHTPEEFKEMGFHLIAHSLTAVYATARALVNIMKILKEKGTTRDDLDQMATFSEFNELISLESWYEMESKFKNFTPKAT
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that promotes osmotic stress and abscisic acid (ABA) responses. Negatively regulates drought-mediated control of early seedling development, probably by influencing proline content, water loss, membrane ion leakage and the expression of dehydration stress-related genes (e.g. RAB18, RD29A, RD29B, AOX1A, ERD15, ERD1, COR15A, P5CS1 and P5CR). Modulates bZIP11 accumulation during rehydration following drought.
Sequence:
MSSIRNTHWCHRCQRAVWLRARDAVCSYCGGGFVEEIDIGPSRAHRDVERDPTFDLMEAFSAFMRSRLAERSYDREISGRLGSAGSESFSNLAPLLIFGGQAPFRLAGGDNSSVEAFVNGAAPGIGIARGTNAGDYFFGPGLEELIEQLSSGTHHRGPPPAPKSSIDALPTIKITQKHLKSSDSHCPVCKDEFELKSEAKQMPCHHIYHSDCIVPWLVQHNSCPVCRKELPSRGSSSSTQSSQNRSTNGRENSRRRNIFSNLWPFRSSSSSSTQNRRDTNNTATAEEGHYHHHQQQQQQHQHQHQQQQSHMGYSGWPFDY
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
METTDRAEISLSRAEQPSGAVAINNVRSEFRSKAEANKIRKVKAAEKSYGRGRKIDVKNVKDKKLKRNLTNLEEKYQTATLKAKEAEILLENAGGFLEAEHELERTYKVRQEDIVSEVNIEVAQKKFDLKLDQLGPYICDFSRNGRDLILAGRKGHVATMDWRDGKLGCELQLGETIRDVKWLHNNQYFAVAQKKYTYIYDSQGVELHCLRKHVEVSHLEFLPYHFLLATLGTNGQLKYQDTSTGQIVTEIATKLGTPVSMTQNPWNAILHVGHQNGTVTLWSPNSSEPLVKLLAHRGPVRSMAVDREGRYMVTTGQDCKMAVWDIRMFKEVNNYFTRAPASSVAISDTGLTAVGWGTRTTVWKGLFSKEKPVQEKVQSPYMTWGGEGKRVERVRWCPFDDVLGVGHSEGFSSLIIPGAGEANFDALEVNPYETKKQRQEGEVKQLLNKLAPEMIALDPNFIGTLDLRSAKQREADKDLDAGPPDLEEEMRNRARGKNSALKKYLRKQKKKNIIDEKRLKAEEMYKQMQEKNGERHKEKVAELGPTLARFARKE
The following text describes a protein:
Function:
Component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity.
Sequence:
MPFLIIIPVLPPHLRDEALRGGTAKHGREEPLPQWSDPAPKPQDQLPLGAAGTAAARVSLRCVHRVGQSDSFFSPPGQMSCNPSFGGIGKGHLMREVDALDGLCGRICDLSGVHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQREILNTPLLTVQEASVEDLILTKPDSGYPGKCRVSGVVLADGSKVPAESVILTTGTFLRGMVLIGLEEHPAGRLGDQPSVGLAQTLEELGFVLGRLKTGTPPRIAKDSVNFSILKKTTPDNPPVPFSFLSEKVWIRPEDQLPCYLTFTNSEVEQIVRENIHLNNHVKETTRGPRYCPSIESKVLRFPNRVHQIWLEPEGLDSDLIYPQGLSVTLPAELQEQLITRIKGLEKAKIVQPGYGVQYDFLDPRQITPSLETKLVQRLFFAGQINGTTGYEEAAAQGVVAGINASLKVRGKPPFIISRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTFRGYEEAGCVSRQRYERASMVKSSLEEGISVLKSVQFSSTKWSRLIPELPISLSKSVPCSALDILTYEEVDLEKLAKVIPDPLKKFVESRELTERLKIEAIYETMISLQQQEIEEVRRDEALQLPEDLDYMSIQTVSLSHEVREKLNSNRPRTIGAASRIPGVTPAAIVNLLRFVKSSQRTEEALGDFPQTARHGCGTHRPQRRKL
The following text describes a protein:
Function:
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Subcellular Localization:
Cytoplasm.
Sequence:
MIVLRSKSPRRKQILESLDLDFRIESEDIDESSLKDEHPLEYLKRISLSKLGTRSKDELLISCDTIVVQENSILQKPENFSQAIEMLERLSGKTHIVYSGLGIYYNRLEQFAFDSSKVHFHTWNKEQIKKYIERYSPFDKAGSYGVQDIEGPVQSFEGSYTNILGFPIRMFFQYHELWKKYLKGNQA
The following text describes a protein:
Function:
Transcription factor. Involved in motor neuron fate determination and maintenance. In concert with unc-37, represses the expression of VB-specific genes such as ceh-12, thereby preventing the adoption of VB motor neuron fate. Regulates synaptic specificity and the pattern of synaptic input to VA motor neurons, and, depending on context, acting in opposition to, or supported by, Wnt signaling. Required in patterning of the synaptic outputs of the postmitotic DA class cholinergic motor neurons. Acts as a transcriptional repressor to counteract gene activation by transcription factor unc-3 in a subset of motor neurons, probably by binding to specific promoter elements. Has no role in axonal guidance or outgrowth.
Subcellular Localization:
Nucleus.
Sequence:
MIGALHACVDAEPKIINDIWADFWKSQINSVLLNPSDGSETYLASDNGKSTSSREQSTSPDDDNLLMNEDDGIALEDDNDTGESAAKRRRTRTNFSGWQLEELESAFEASHYPDVFMREALAMRLDLLESRVQVWFQNRRAKWRKREQNRNGSSEIKKDDGEQMETKALPTFPFSIDSILAVSRVPRGRRPNAKYPRVQACKNLSPFMIPLFPITQPGGNVIREKSPPLPTQQSQIVATNALTTVAELLKSV
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MADANNLKIDIEVPFPSERFAEIAYHVLRVEKEPKRSGVTKEITYHKNILHVKFSAQLARQLRVAVSSFFDNLNLMSETIEFAGDPVSSTYSHF
The following text describes a protein:
Function:
Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MPGCSRYSGELTEESLRSGDKSLELEEIRQDGPLPVTEADATLPTSQVPSDVANWDAERLSPGWELVAILCVCALAGVVGTHIRILLEDAFNYEGLHIMRKWDCLFQDLPANMIGCFFMGIVGVTCKAQIAKYSELIALGLTTGLMGSITTYASFNQDMAQLFVAGRWEKALFGIILGLELPFVSLLVGINAGQSLVWFWSCFQKRRRVAIRITPDNLKRRKAVAWTAAVLWLGFLLPLNIVIAAFKWGDVGKHIQAIAACISPLGVWLRWYLSRYNGGFMKGSPYAWIPWGTLAANVLASMCLTLDKMGDVQITSHVWSVWLMALGKGVMGGLSTVSTFMVEILKLAEGGSSGKAYAYIAVSLILTQICAFILYGIPVWVEQFPRAFPGHESHNDVP
The following text describes a protein:
Function:
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MREALRSLLVALQFLTRLPVRLSAMPTPEQFGRAVLCYPLVGVLIGVVLYAAARSLDGTPPLLQAALLLSLWVALSGALHLDGLADMADAWVGGLGDRERTLAIMKDPRSGPVAVVVLVLVLLLKFSALAALLGQGEAGLLPLAPWLARSSLPLLFLTTPYARPGGLGQAIAEHLPARSLPWVLGVSFGLALAFGLAGLLALLVTLMLFAWLRSRFLARLGGTTGDTAGALVELTECAVLVALAL
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MGNNSSSSYKNNNNNNNNNNNNNNSNGNFNSFHTPMQLNGTNYTNPKCKSKEEILSVLNKQPFPIAEEINDLIISLRQSFYEGHIDTRQLLSRLEYIFYASEDFEKVKSYFVSLSKPVCCSRVWGSSYENKDTNKNLNFFYRCKTCALSPNSSICFECFKAGPHEREKHDYSMSFASYGGSCDCGSLDSWKRSGFCSEHEHPEVDYSPSGDMDKLHLLTTHLVLRHILLIFLNITFDLHSNNSNSNNNNNNNNNLTSFTTNTTTTTTTTTTTTTSTSTSPTKKQQQQQQQQQQQQQQQITLNTIETKETISIKILKWINDIAHVSRSISHVLSEELCYQSLDPMSLDPNNIKPLIFTCMEYQLELIKNLQQQQQEEEGQEDEEKEKDSLKLTNEEIEFLKFEFKLPNEFSPPLKRILFIEQKTIRQEYMFIFLFLLCEHTFKFGFSQSYLNVYKSLCYKDTVDILFRFSPQVFSVCSVSEQFSIGMEFGFLDCIFESLFFHLQASDKLDKNHIAIVSDLKTILQHRNIAHHMIFEKRKYLKYYINLLQIIQSTSNDIKSGGIGGGGGDELNDEDYYYHHSNNDGTNNGDYQRRYIDTHIPYEDINWIQFFQIDTELKDISNILIDSLSTQDTLQGLRDMITFIATNLITDPQIQELQPYYNVMVSKKDIYLGEKSITTTLPFHRFLGVTTHKVIQLYSGMVTIKELLPIDFNCFAFLYPLLNANVYTQQVNSNYWVRNGDVNVKKKAYVYSLFFLEMDLSLIQMIASLINVNDFCIFTSKEFGALLPYGSTTVIGGNEKNNLFRPSSNVSLSSNHHRYSHFLKFIIEVLQERLFFMTPDQHTKYTLIQILCSKPKTHSQIDSVMNYVERELKYEHILKEISDEIPPSGDNPTNYKMKNEFWKNFNLYYPIYTPYILGEESLQAFFEYKKQLKISYQNSLPMPPKYENLSSIEFEKSSPSSSSSSSSSSSSSSSSSTPKIIEESVDDNFPTTTTTTTTSTATTTITTTNNNNNNIIIKKDNDQIKFFEIMNSDYLHFMITNILLSFIQGRETNEIGCGINDAFYLLVLILENKIKLKSSSSSSTTTTTELIKTEIPWTILDQPLNSFSTYGDAILCILQKFNFFGIGRSTLDVLLEYYQESYTNNIYLDKKEYIDKCLSILYNIDESIAKRIKTRSPTFSPIKNLSLNSDGSVISSNDDNSNSNNNNNNNNNSNNNGGNQNNNQNNNSNEDDGDENNSGKRDNEKKLKDAKKRQAEIMAKFAKQQTQFLQNVDDLGYDEDDDEMDYSYSAHNSGKKNKQTPISSPGKTTSTTATSSPSPFVNSSSSSNGFESISKSKEIFNDNIKNQSCVLCYESHISDSDPLSLISFLQPSKMIAYSKCQYVERKYPELTKYDFFVGSEPTYYNFPQKRDMNTLNYMSSLHIRSCGHYIHKKCHSIYFLKVLTQEQDENFKPSLKEFLCPLCRRVANIIMPTYTESSVTCSPIISYFDITNSTNNNNNNSNNNLNNNLNNNNNNNNNNSNSNNNNISGSNGLTNSNGIGSSSNSVNNSPNFGGNANNLSIWVDSLKKRLKDLVVIEPRSKLFFSDWLSTLIPSMIEGITPWVLYQIVSKNIEFLELASRLVELSPSSSSNNNNNSNNNNNNNNNNNNNNNNNNNNNNKKTTYPIGNELFSRDMLTIHTLFNLIGSLNQSSIDIDIIKGKSGSILSVDPFSLFIVLVSILGTPTNQDVEIITTLVLNLFITQFYLTNLYLEKEINKKQVKSISQIFQQTYTAASTSTLRMKYEDRLKKVMEPLARCLYIAYQFLQPPQISGDGINYINREDLTNKEKIYSRLGINSMEEIVNRALFNNPYLSQWLSQMESKKVDPFFIVEYRRPKFITLPESFEDFFVSSAQRECMNCKTKPEFSAVCLLCNQLVCSHRSECCNDDDKHYNISEGYKHTLKCGSFKVGFFLETKAPRIDILRDHRKSIFNNGYLDQYGESDPTLDRGKPLLRNDNNFQDLWNCWITHSIEDRFLSNSTLSSRTF
The following text describes a protein:
Function:
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
Subcellular Localization:
Cytoplasm.
Sequence:
MIAGSMVALVTPFDAQGRLDWDSLAKLVDFHLQEGTNAIVAVGTTGESATLDVEEHIQVIRRVVDQVKGRIPVIAGTGANSTREAVALTEAAKSGGADACLLVTPYYNKPTQEGMYQHFRHIAEAVAIPQILYNVPGRTSCDMLPETVERLSKVPNIIGIKEATGDLQRAKEVIERVGKDFLVYSGDDATAVELMLLGGKGNISVTANVAPRAMSDLCAAAMRGDAAAARAINDRLMPLHKALFIESNPIPVKWALHEMGLIPEGIRLPLTWLSPRCHEPLRQAMRQTGVLA
The following text describes a protein:
Function:
dsDNA-binding protein that contributes to the ionizing radiation resistance of D.radiodurans. Plays a role in DNA repair and genome reconstitution, and is necessary for recovery from severe genomic fragmentation as a result of exposure to severe levels of ionizing radiation. In vitro, binds to double-stranded DNA carrying strand breaks and stimulates the DNA end-joining reaction catalyzed by DNA ligases. Thus, PprA plays a critical role in a non-homologous end-joining (NHEJ) pathway for the repair of radiation-induced DNA double-strands breaks. Cannot bind to dsDNA without strand breaks or single-stranded DNA.
Sequence:
MLPLAFLICSGHNKGSMARAKAKDQTDGIYAAFDTLMSTAGVDSQIAALAASEADAGTLDAALTQSLQEAQGRWGLGLHHLRHEARLTDDGDIEILTDGRPSARVSEGFGALAQAYAPMQALDERGLSQWAALGEGYRAPGDLPLAQLKVLIEHARDFETDWSAGRGETFQRVWRKGDTLFVEVARPASAEAALSDAAWDVIASIKDRAFQRELMRRSEKDGMLGALLGARHAGAKANLAQLPEAHFTVQAFVQTLSGAAARNAEEYRAALKTAAAALEEYQGVTTRQLSEVLRHGLRES
The following text describes a protein:
Function:
High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDTENRSRADLALPNPQESSSAPDIELLEASPAKAAPPKQTWRTFLKKELEFLGATQILVGLICLCFGTIVCSVLYVSDFDEEVLLLYKLGYPFWGAVLFVLSGFLSIISERKNTLYLVRGSLGANIVSSIAAGTGIAMLILNLTNNFAYMNNCKNVTEDDGCFVASFTTELVLMMLFLTILAFCSAVLFTIYRIGQELESKKVPDDRLYEELNVYSPIYSELEDKGETSSPVDS
The following text describes a protein:
Function:
Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR). Can also dehydrate L-lyxonate, L-mannonate and D-gulonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate.
Miscellaneous:
MISCELLANEOUS: Reaction proceeds via a syn dehydration.
Sequence:
MTLPKIKQVRAWFTGGATAEKGAGGGDYHDQGANHWIDDHIATPMSKYRDYEQSRQSFGINVLGTLVVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEGKCVSDIKLIHDQMLSATLYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAVRDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGEDFWLMLDCWMSQDVNYATKLAHACAPYNLKWIEECLPPQQYESYRELKRNAPVGMMVTSGEHHGTLQSFRTLSETGIDIMQPDVGWCGGLTTLVEIAAIAKSRGQLVVPHGSSVYSHHAVITFTNTPFSEFLMTSPDCSTMRPQFDPILLNEPVPVNGRIHKSVLDKPGFGVELNRDCNLKRPYSH
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MVLSRRVSVTKATHIEGETSVSAEYTAPFCGKDLDKPDSSGAAARCLAVNNDPTLSRTTASLGMPVGQMTIFYCGKVNVYDDVPEDKAQSIMHIAASPVQFPQEQQPVDDTIIIHPLTSLSKAVSVKAGLDSPVALLPALQTVKMSENSRALADECISLREGTPVEGPSTRKASVQRYLDKRKDRFKSKRKAGITSCTSLDVQFNHQKNNQIPNDFLNRSNTCSPPPIKPPSTPTRCSSVDNDSLRNLCGSTDLNN
The following text describes a protein:
Function:
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Sequence:
MPRTENFTEALQLTHNFDPSVPYSARLEAERYLMDLLESAEGLKLSFHIISNEAVDELRSFWAFNTVMHHLPKLAVTVDAEQAQEFYHTLFSFIHRYLFASPAVTPIDYVINKHAQMMVAGLQLFYPARWPSIFDDLFEMLHRRSTSPCLPTADLVTIYVLRIFEYIDERVVCVRDRQERGKQQQARDMELKDAMRERVLPKAADMWYNILISDACVRNPDMAKLCLSVMQTYIEWADVNLFMTENWIHLLYFLLTVPPLRVAACECLLSLVEKKQLPGLKMRSLRTLSVVDSVPRMMSLFELPPPSEAAVLFMEAVAKFAVAVAGQFLSLLDTCASLAQQQPSTRSAATVEVSGVVLHDEPFTVTADLLDGLAGALHAVVGQVILVLHLNLFDVRDALLPFLQVYLKSAYLLESEAAELLATLFHQTRIPGVAYDEDRIWDDTVIDQRKTLHNLLRLLHRRRPDLVMSHLHSLVLTGLSRLSEGGDVARASTAKDDADFTDPEVLEAALRYLYEIGESLRLESLKDPNDSITQLLQRVLTTEAVVSGEATCVHLAFFEVLGRYYLFFTYHPEFIPLLLQRLLLQPCGVMSRSDRVRARICYLFGYLLQLLKSRIGTYAADMIKALHSIVTTAPQLQPGDRRELYEAIGILLSICSEEASPALDGGSSEALRLLTASASIDDYGATAVSSAVLAEAAPLLGRKAELVHTVVGSALQTLQQASASCAGMNGGAAGCSGHAAARSVAVAERTVADVISFLSALAKGLGSTGSSSGAGSAAGSGVSNRSVSPPNGSVPGPWRIGTNPNASGVAVDGLLAACGASSDASLSTSSAMSATGLLVTQMFLQVTQRVMEVANQMAGSAAVRDVVGQFFHQLINTLPYEMLRPYIEGYVTVCLNWMEAVPELSKVLRLMFQYANKAGSRGVLSVARLTPLLWHRLCAVGELSEASPVVCMGVVSESARERVNVYKQLFTFLFSVSTWGCVAAFALMPSACWMSILRQLCYALTLPTELELPKSALQVLEKLTQELTDPVVAQAVAQYSSATDVVDAATAQRNQHVFSECLLQEALPTAFGALADPSFDLDDAKNFLLLGEVLQFFRVLVARYGEPAMQVLYERVAPYVGEATAMECCTVIRDQPRVNAALKVKMKQLLSRVHEYQRRTPANRLS
The following text describes a protein:
Function:
Required for the promotion of megasporogenesis, or promotion of germ cell formation from somatic precursor cells. Acts redundantly with WIH2. Functions in a genetic pathway downstream of SPL/NZZ and WUS and together with TRN2 in promoting megasporogenesis. Involved in resistance to abiotic stress.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MYHQEQHPVGAPPPQGYPPKDGYPPAGYPPAGYPPPGYAQGYPAQGYPPPQYSQAPQQKQNAGMLEGCLAALCCCCLLDACF
The following text describes a protein:
Function:
Postsynaptic RAC1 GTPase activating protein (GAP) that plays a key role in neuronal morphogenesis and migration mainly during development of the cerebral cortex. Regulates excitatory and inhibitory synapse maturation and density in cortical pyramidal neurons. Mechanistically, acts by binding and deforming membranes, thereby regulating actin dynamics to regulate cell migration and differentiation.
Subcellular Localization:
Cell membrane. Cell projection, dendritic spine. Postsynaptic density. Postsynaptic cell membrane. Cell projection, lamellipodium. Cytoplasmic vesicle, phagosome. Nucleus. Cytoplasm, cytosol.
Domain:
The F-BAR domain mediates oligomerization, binds membranes, and induces plasma membrane protrusions.
Sequence:
MTSPAKFRKDKEIIAEYETQVKEIRAQLVEQLKCLDQQCELRVQLLQDLQDFFRKKAEIEMDYSRNLEKLAERFLAKTRYTKDPQFKKEQNILSPVNCWNLLLAQVKRESRDHATLSDLYLNNIIPRFAQISEDSGRLFKKSKEVGLQLQEDLMKVLNELYTVMKTYHMYNMDSINAESKLKEAEKQEEKQMSRSVRHEEKQTPRSPDSLTNIKIEDKHVRRSSVKKIEKMKEKRQAKYTENKLKAIKARNEYLLALEATNSCVFKYYIHDLSDLIDCCDLGYHASLNRALRTYLSAEFNVETSKHGGLETIENAAENLEANSDKQRLMETYNNVFCPPMRFDFQSHMGDMVGHLCAQQPVQGELIQRCQQLQSRLSTLNIENEEVKKTMEATLQTIQDMVTIEDFDVTDCFHHSNSMESVKSTVSESFMSKPSLAKRRANQQETEQFYFTKLKEFLEGRNLITKLQAKHDLIQKTLGESQKTDYCLASGRRDSTVRKQEAIQIIPLMVESCIRFISRHGLHHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLENALFPKEVFHDLMSCVSIESLQERAVHIRKVLLSLPSNILVIMRYLFAFLNHLSQYSDDNMMDPYNLAICFGPTLMSVPEGHDQVSCQAHVNELIKTIIIHHESIFPGPRELEGPVYDRGGAPEEYCDSPHIEPPLVDEPAPDTVSVIHNSDDVKSGPLTVSESDPIEAIARFDYSGRTNRELSFKKGASLLLYSRASDDWWEGRHNGTEGLVPHQYIVVQDMPDGYAGRGSPKADLEGSHDSVEEKVSTRASASSPTGGHVADIYLANLNKLRKRPEATSIRRTIRPVEEGSSGAAGGLKTSSMPAGGLAKDSSDKRPVSAHSVLNSITRHSSLKTKVEGPQVRKSTPTGRSKSFSNHRPLDPEVIAQVEHSSQDIEATMNTALSELRELERQSNVKHAPDVVLDTLEQLKSGGTSEPSSPLHSRLLREAESSQHPLQRSASSASDMPSTFRPSKTTGPKSPLSSMTTASGSTFRDNKPPATRPKPVVFPKSSSAGGSPAMGSPTTTIPPTPPPPPPPTDKSCPV
The following text describes a protein:
Function:
Assembles to form an icosahedral capsid with a T=7 symmetry. The icosahedral capsid is about 60 nm in diameter and composed of 415 major capsid proteins. The assembly is primed by the interaction between capsid assembly protease and portal dodecamer, and major capsid proteins assemble cooperatively to form the procapsid with the help of capsid scaffolding protein. Major capsid protein forms hexons and pentons of the icosahedron. Viral genomic DNA is packaged into the procapsid through the portal vertex (By similarity). The packaging triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while the capsid thickness decreases. The capsid decoration protein binds the expanded capsid and stabilizes it.
Subcellular Localization:
Virion. Host cytoplasm. Note=Forms the capsid icosahedric shell.
Sequence:
MSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQIPGLVNMALYVSPIVSGEVIRSRGGSTSEFTPGYVKPKHEVNPQMTLRRLPDEDPQNLADPAYRRRRIIMQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVEVDMGRSEENNITQSGGTEWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVKEKLDTRRGSNSELETAVKDLGKAVSYKGMYGDVAIVVYSGQYVENGVKKNFLPDNTMVLGNTQARGLRTYGCIQDADAQREGINASARYPKNWVTTGDPAREFTMIQSAPLMLLADPDEFVSVQLA
The following text describes a protein:
Function:
Proton-coupled polyamine antiporter involved in the translocation of polyamines from cytosol into secretory vesicles prior to their release via exocytosis. Uses the electrochemical proton gradient generated by a V-type proton-pumping ATPase to couple the efflux of protons with the uptake of a polyamine molecule (By similarity). Facilitates vesicular storage of spermine and spermidine in astrocytes with an impact on glutamatergic neuronal transmission and memory formation (By similarity). Upon antigen stimulation, regulates polyamine accumulation and release in mast cell secretory granules, which in turn potentiates mast cell degranulation and histamine secretion.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Colocalizes with VAMP3 and VAMP8 in mast cell secretory granules, which are distinct from histamine- and serotonin-containing granules. Partly colocalizes with SYP in synaptic vesicles in hippocampal neurons. Colocalizes with SYP and VAMP2 in secretory vesicles of astrocytes (By similarity).
Sequence:
MDEAGSPAPAGTGGGDDPGGSTRETSRRLSREQIFVLVSAASMNLGCMMTYSILGPFFPKEAEKKGASNTMIGMIFGCYALFELLASLVFGKYLVHIGAKFMFIAGMFVSGGVTILFGVLDQLPEGPIFIAMCFLVRIVDAIGFGAAITASSSILAKAFPNNVATVMGSLEVFSGLGLVAGPPLGGLLYQSFGYEVPFIFLGCIVLLMIPLNLYILPSYAQESDPGKQSFWKLVTLPKMGLLAFVIISLSSCFGFLDPTLSLFVMEKFSLSTGYVGLVFLGLSLSYAISSPLFGLLSDKMPTLRKWLLVFGNLITAGCYMLLGPVPLLHIKSQLWLLVLVLVVNGISAGMSIIPTFPEMLSCAYANGFEDSISTLGLVSGLFGAMWSVGAFMGPILGGFLCEKIGFEWAAAMQGLWTLLSGVSMALFYLWEDSTARRRSKAQNSLGTEEERAALLPNDT
The following text describes a protein:
Function:
Plays an integral role in secondary cell wall biosynthesis by the polymerization of cinnamyl alcohols into lignin and by forming rigid cross-links between cellulose, pectin, hydroxy-proline-rich glycoproteins, and lignin; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MGCGATHLSLALSLMALALAGISIYKNTHVATVMEDFDVKMESNSNILEQNSDMLSQEFCIFAAVGTVVAEAIRRERRMGASLIRLFFHDCFVDGCDGGILLDDIPGSFQGEKTSPPNDNSARGYEVIDQAKQRIKNMCPGAAVSCADILALAARDSVAMLGGLPYPVRLGRRDARTANFIGSLTQLPAPFDDLNTQLRKFRAKGMSAQEMVALAGAHTIGFARCVTMCNDNNINPAMKSTLKCNCPVNNNDTNLVPLDLVTPDFFDKAYFDDLNRNQGLLFSDQVLTGNSTTNDVVRRYSNNGFLFLRDFNAAMIKMGDLPPSPGARLEIRDVCSRVNGNSIADM