lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MDSAAPDCTAKCRSLKHALDVLSVITKGSERQIKIFLSSYCYNAATVKDAFGRNALHLVSSCGKKAVLDWLIEKGVDLLVKDKESGWTALHRSIFYGHINCVWSLLKHGVSLYMQDKEGLSPLDLLMKDRPAHVVFKNTDPTEVYTWGDNTNFTLGHGSQNSKHHPELLDLFSRSRVYVKQVVLCKFHSVFLSQQGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLSGHSCSQVAAAKDHTVVLTEDGCVYTFGLNTFHQLGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKVDPEHLTENGGQKICILAMDGAGRVFCWRSLSSSLKQCRWAYPRQVSISDIALNRNEILFVTQDGEGFKGKWFEDKRKNSEKKADILPNLHHSSSDVSCVSDTNSVYERIRLEKLPFAHRAVSVSTDPSGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDSFHDVTFQVGNRLFPAHKYVLAVRSDFFQKLFLSDGTLLELTDVYRKDEDAAGCHLFVVEKVHPDLFEYLLQFMYTDTCDFLTHGFKPRMIMNKKSEDSKGSPESRLHAVNCHVDDKQKSAFEVYRSNQAHTLSERQKSKPKSSKKGKGVGEDDPVKMLQNVAKKFGLSNLSSRLDGVRYENEKINVIAKKTGNKLKLSQKKCSFLYDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSRSWIEASSCAALEMPIQAEILKVILDYLYTDEAVVIKESQNVDFVCSVLVVADQLLITRLKEMCEVALAENREYFKSREVLFPQILT
The following text describes a protein:
Function:
Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step. Together with PAT1, the LSM1-LSM7 complex binds to osmotic stress-activated mRNAs to attenuate the osmotic stress response, probably by limiting ribosome access to the mRNA and consequently translation.
Miscellaneous:
MISCELLANEOUS: Present with 3490 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm. Cytoplasm, P-body.
Sequence:
MSANSKDRNQSNQDAKRQQQNFPKKISEGEADLYLDQYNFTTTAAIVSSVDRKIFVLLRDGRMLFGVLRTFDQYANLILQDCVERIYFSEENKYAEEDRGIFMIRGENVVMLGEVDIDKEDQPLEAMERIPFKEAWLTKQKNDEKRFKEETHKGKKMARHGIVYDFHKSDMY
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MQVMEAAAWRQPSQAPTADLVGLQIGLATTSEILGHSVIESRSKDTLISLVDPRLGLPAEDERCATCGGTNYDECTGHFAHVKLTQPIFHPNYIRCVQRVLQKICLACGVPKVKKMKSFSEEAANLKQNFRDIDSEDVGGNGEHPVLLEADAIEKDADDVVILLSSDEEEYPRDILRVVPSGPMDFLIRSTNESAIADLPQLKSYKSKSKAHANGFSHVDVTRKSTRKSSSKKSSSTQNPVKIYKGTPAGLDVLNADTLRTAEPLDTNTCPYCSPGYPDYRHILVKILPVKGRKKNDVSQIILLEVQGSDKGEKFLLPHDFWSFIKGAAYPENEEVPKSHVLSPLEALSILKKISDTAIGKLGMNGLVARPEGLIMKCVPIPPNCTRTTDYKYVSNTTAVRFGTDRVTRTLQNLVNEIGRIQRTRTGKIMKRGQRDEVKVLQVLTAEYLREKGAPKAVPGKEPLKKDRNGRFTKQDDHRWTKDWISQNYLGKGGNYTARAVVAGDPSLAIETIGVPLEIAQKLTVPERATKWNRSKLQEYVDRTQMLQQGSGKPGATRIVRNEEAFQVWANSTHTVQIGDVIHRNIQDGDFVYVNRPPSVHKHSLMALKVQVHYGLVLTINPLVCPPFNADFDGDIFHVFIPQSLQAIAELEHLMAVPQQIISDHGGQPLLGLTQDTLLAAYLLTSSKLLVDKAGMDQLCLWALKQPPDAAIVKSPKGGPFWTGEQIFGLTLPTDLQVGAPHEEVFIEGGEVIRWSNGAKSLRKDSEGIAAALCVQLGPVALVNYLNTATGLLHAWLQMHGFSTGLADFQVTSNSADRQKMLKSIFEDYYQKSIQESCDSVRILDAKVQAMGQEVISSPDHLTRNINFLEQAAQQTFRNRESEVESIVMKYAARDNGLLMMVRSGSKGSRGKLLQQIAGMGLQLYKGQHLLPFSGSRRSSMSNSSELDWWEDKGLVRSSLVDGLNPSELFNHVIADRTVILRKHVEVVQPGTLFKSLMLFLRDLHVMYDGSVRNQCGKNIVQFCYGGAIGVLKRSIPKERLSRSQFEVVNPATPIVTWEEDDLKRWPLSILAGEPVGVLAATAISQPAYELMLDAPCLNGPFKPRPLELVQETLYPRAKSVLKPIDRTAIIRLVNCPCTQPLCLERRVLAVQAHLKKISLKAIAESCAVEFWNMENFEVAGPSGEALRMGSPWLGHIKLSLNLMKQLQVDVELMVERLRQRFSGIIKNPKKHPMGQIFFCVSYNCGISNGLCLHFSPKLPNKMQNQRNDEIYNTALLALLLKIRGTIISGLLDCTVKGDERIESVIIVSEDPSRTTWHRGLTCNQELEEELVLEVVVSPTKSKSKRGDAWASVKQACLPLMHMVDWNRSMPYSIQEIRHALGVEASYQMISQRLGLVLDKTAPHTRSVHVKLVADMMTFSGDANGFNFSGFQDMNKSTGISAPFTEASFQKPIKTLMDAAGRGATDSVESVLASCVWGKEAPLGTGSNFELFWQPSKDQSRLAASRKAEKDVHMIWKDLHEKCISDKVLPPSPPPSLPGLPTLPDGDVDLDDGAGFSPLHASNDAADDTWGSPHRNNGGDGVAWGDSPVVRDDDGGWGAVGKGNDSNEVDGYDQDNSTGASKELSGWSKPASERSGWGSMSDKEGSSRNAWDDFGKEDRHEGWGDGATEPINEGGWGSLNNEEGTTSGAKCSSDWGTNAVQEIGDGGWDAVSIEVPEGDGWDSLKVPQTENAEVGSSEHADRSYGPGADGVSQEGQFRARGEESRRGGRPWTSRDRRRWRGRGSFGKDRGSSGRMSPGNRQNSGTISRQEQTPWVQGSTKADAWAKHAWASFGSSQGEVQAGGDGWDAVLPDNCGASNRAHSTYPIAGSMPPTSRQDEVEPECKDIDDLVKSMRRILFNPRNELGGRLSDEDDELVQTVLAYHPKLSEKAGCGTAYIKVDRSAGFVNNRCFWLVRTDGSEIDFSFHKCLKEKVAREFPSFLDRYDDVYQAHKRPFPTANFEENKSAAQGNIDAGPSAAHLLEDMPIDHEDLDARPAAAHLPEGIPIDQEDLDAQPAVAHLSEDTPIDQENLDAQPAANSISVDTHFDQQEDIDTQTGQESAPSIGVSSATKLICKKLTEPVHEHQDTSGPH
The following text describes a protein:
Function:
2-oxoglutarate-dependent dioxygenase catalyzing homoarginine 6-hydroxylation thus producing 6-hydroxy-L-homoarginine. Guanidine (Gd) is in turn synthesized by the spontaneous conversion of 6-hydroxy-L-homoarginine to (S)-2-amino-6-oxohexanoate (RHEA:79843); guanidine is a nitrogen-rich compound that can serve as a defense or signaling substance.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MATNFKSLLPVIDISPLVVKCDDANMAEDAGVAEVVGKLDRACRDAGFFYVIGHGISEDFIRKVRVMSHQFFELPYEEKLKIKITPAAGYRGYQRIGLNLTNGKQDMHEAIDCYKEFKQGKHGDIGKVMEGANQWPENPQEYKELMEEYIKLCIDLSRNILRGISLALGGSPYEFEGKMLTDPFWIMRILGYPGVNQENVIGCGAHTDYGLLSLINQDDDKTALQVRDLAGDWIPVIPIPGSFVCNIGDMLKILSNGVYESTLHRVINNSPRYRVCVGFFYETNFDAAVEPLDIFKEKYPGKGTSQVFKRVVYGEHLVHKLQTTFQNLVEHS
The following text describes a protein:
Function:
GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1.
Sequence:
RGTFITVSKKQNWAKCSAACRDNSCIPSTDGPRSLGSRTQEWEGCQGKSQVLSLKSAWSNSKECSQKASEIPPKREAVSYKGSSEQYSFSSGVPELTRPCLSYTDHCAASSSVKITGQGAYLQSLERSSRAWVLSTGKPQASDEGLRFPPNCLAEWKQGTDGESKGNIWYNPIPEEEDSRCGKMAADYGNPWKKRELEGSMDNKKECWARKRAGIIGQPNRVPRIERHNSDTQALAGQSEPSGASGPSDSPGAQKKPGMMDRIKSPGTVRRLSMKMRKLPELRRKLSLRSSRSQRQGQTEGTSPLNARKESGNVISRYHLDSSVSAPERPPRRSSRRGKSASKGGYLSDGDSPELIAKHDPQEGAGVLDPSAFRPYSLAEQPRCAQRLSGLMSVHLYRLEEVKSPRVDSKEVFCAIQVDGVTRARTALLTCRGTFLSLNHTFNLELERAQLLKLVVFSRDPSASRNRVCCLGAVAIPPLFRGSRSQQLAVKLEPRGLLYVKLTLVEQWDTPAKPSDQEPRVFGIELRQLVEKEGSAIKVPLIIQKSVSEIEKRGLKVVGLYRLCGSAAVKKELRDAFERDSTAVTLSEDLYPDINVVTAGILKDYLRELPSPLITRTLYEVVLDAMTKRPPKSTLSKRESDAQRSAHTVTLLDCLPEAEKATLTVLLDHLSLVASYSECNRMTCQNLAVCFGPVLLTPTQEPWRPGGRSFAHSEEIASAVDFKRHIEALHYLLQLWPLPKGRAPDPPDPEPPVSQNSLRRHQRPVLRLDLSKDSVVSRRGRGRLESPPCNRYAGDWSVCGRDFLSMPEADYDEVAGTDSDEEEGRGELGKRDWDPQRPLYVSDFTLDPQDIDLDAPFTTRLSLKDFDTLISDLERELGKQINICL
The following text describes a protein:
Function:
Component of the plastid division machinery consisting in a binary fission accomplished by the simultaneous constriction of the FtsZ ring on the stromal side of the inner envelope membrane, and the ARC5/DRP5B ring on the cytosolic side of the outer envelope membrane. Positive factor of chloroplast division required, with a dosage effect, to mediate the recruitment and dimerization of ARC5/DRP5B at the midplastid constriction site in the cytoplasm at plastid outer envelope membranes (OEMs). Prevents ARC5/DRP5B GTPase acrivity. Relays plastid division site position between stroma and outer surface via interactions with the cytoplasmic ARC5/DRP5B and the inner membrane ARC6 that recruits stromal FtsZ ring. Binding to phosphatidylinositol 4-phosphate (PI4P) modulates negatively chloroplast division.
Subcellular Localization:
Plastid, chloroplast outer membrane; Single-pass membrane protein. Note=Plastid equatorial positioning in a discontinuous ring mediated by ARC6. Colocalizes with ARC5/DRP5B at the chloroplast division site.
Sequence:
MEDEEGIGLILARATELRLKISDCIDNSSTTVSDNGDGNEDLSPGEGRKSEIIGNQDKDFDSISSEDVDEAEAERLLRIRDALEALESQLASLQNLRQRQQYEKQLALSEIDYSRKMLLEKLKEYKGKDFEVLRETTTFAGERVDYENDLLLPPYPVHPPLSLGLDNNNGYLSHLPSKKKSDANGFGSGHVRNEAEAKSPNGGSGGSSHGVIRFLGSVAKIVLPIIGVISLLSASGYGPEMRKRGASLNLFGLLPHRATRGKRTPNQCPPGKVLVIEDGEARCLVKERVEIPFDSVVAKRDVTYGYG
The following text describes a protein:
Function:
Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Sequence:
MSQMLNQAANMVTGDAKYRQMAEYTIDQDDKTPYTTYFGVKVSDTDNSLRAGARGPTLLEDFHNREKIQHFDHERIPERVVHARGAGAFGEFKLHTPLTGITTAKVLTDTSKVVPAYVRFSTVAGSRGSADTVRDVRGFATRLYTDEGNWDIVGNNIPVFFINAQTAHDNAWDFMSLHKPALHMQQWITSDRAIPRSYRMMQGFGVHTFRLINEEGKSTFVKYHWIPHLGTHSLVWDEALKIAGQDPDFHRRDLWDAIEAGTYAKWDLGVQLIKEEDEHKFDFDLLDATKLIPDELVPVQKIGTLTLNRNPVDYFSEVEQVAFCTQHIVPGMDFTDDPLLAGRNFSYPDTQVSRLGINWKHIPVNRPVCPFMTTMREGQMSMFSKNNRTPYHPNRNENLPLTSPKEGGFKSYPAKVSGIKERVQAPKFNDHSSQATLFWNSMSDVEKKHIIDAYKFELSHCTDNLVIQNVINCINEIDHGLATAVHSGFPHLSLPEAKPNHGKRTEYLSQITGKNQIFTAAGRKIGIFLVPGYVYSQVAPLLAAFKAAGCMVKFVGPTLGPVEASDGQSFTTEFTFEGCRSTYFDALIFAGGPDNAFLSKLKVGRLIHAAREAYMHLKAVGAVGNATQWLVDTCLPGEFSPKVKTESSVVQENGVVFAPINPTLHSAQFAKQFLDGVANHRVWDREVSHIAA
The following text describes a protein:
Function:
Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Subcellular Localization:
Cytoplasm. Secreted. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
Sequence:
MSESSGTAFGGRRAIPPNTSNAAENDPPTVELQGLVPRGFNPQDYLNVTNVHLFKERWDSNKVDHHTDKYSNDKLIVRRGQSFYIQIDFNRPYDPTRDLFRVEYVIGLYPQENKGTYIPVPLVSELQSGKWGAKVVMREDRSVRLSVQSSADCIVGKFRMYVAVWTPYGVIRTSRNPETDTYILFNPWCEEDAVYLEN
The following text describes a protein:
Function:
Involved in resistance toward heavy metals.
Subcellular Localization:
Cytoplasm.
Sequence:
MEAIIVYTTFPDWESARKVTRELLERKLIVCANLREHEAMYWWEGKIEEGKEVGAIYKTEVSKWKELRETIKELHPYDVPMIARIDLDKLNREYSEWMARVLFG
The following text describes a protein:
Function:
Serves as substrate adapter subunit in an E3 ubiquitin ligase complex zyg11-cul2-elongin BC. Targets substrates bearing N-terminal glycine degrons for proteasomal degradation.
Sequence:
MIHLSQTMDKSSLPSLSDLCMSLVSSRLELFCEMRDDGSLSFREPLVFPQELADQLLCKMATDGVLNDSTVGIFRNCQQFRLRHACIRTARISAEAFHRALCPHRLVELDASRVNADLTIADILRGLSSNKSLQESLQRLVLNGLTMSSLEEPSRRCFSAMQGLRALSVSNVDFYDWGLADVCLLPRLESLDISNTSVSNLTPLLGLRSRLRYLTMHQLKRLEMTTAQLLAVLSQLEVLQHLDISDDKQFTSDVARQLLETPGILPQLVSLDVSGRKQVTDAAVKAFVEARPGMTFVGLLATDAGFSEFLSGEGSLKVTGEANETQICEALRRYSEREGFVREALFHLFSLTHAIEKPRPDILKLVALGMKNHPTTLNVQLAASACVFNLTKQELAFGIPVRLLGNVTQQLLEAMKTFPNHQQLQKNCLLSLCSDRILQEVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGAELFIVKQLLHIVRQKTCQSTVDATLKFTLSALWNLTDESPTTCRHFIENQGLELFIKVLESFPSESSIQQKVLGLLNNIAEVSELHGELMVQSFLDHIRTLLHSPEVEVSYFAAGILAHLTSRGEKVWTLELTLRNTLLQQLHSAILKWPTPECEMVAYRSFNPFFPLLECFQTPGVQLWAAWAMQHVCSKNAGRYCSMLLEEGGLQHLEAITSHPKTHSDVRRLTESILDGLQRHRARTGYTAIPKTQAHREKCNP
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MAAIRQLIGLTNRAQPTRSRLIPISAPFIQRSHIQSKILPYSVQIRRNFSNQGQKEKGLFSKVFDNIKEGFAKNKELQENIKKFREEAAKLEQSEAYKKISDATEDLGSGAADRKAKLGTFLSKFRTSAGKLYEDVSSSDFVKKGKEVSEDLSNVASEAAKKVSDSSKSVGETQTFKTFSEGVKTIKEDLFEEGLNRAQPYRSPANIIGYYFIEKLHKRTESDLQSKMKDEQQIQEDTDTTGVVLHKDSRWYQQWKQFKDNNPVVNGLFNLKMKYDESDNVVIRATRVVTDRLSDAFSGIFSPSEMSQTLAEISKIDPNFSKEKFLLHFQHRIMPSVLEAFLRGDLPILKDWCHESAYSVLEARIKQLTGMGRKLDFKVLDVRDIDIAMAKIMEQGPVLVMTFQAQQILVLRDSSGKVVEGDENHIENVQYVWAMCRDQSIYDAHSAWRVLEFAMQASSSWLKTVYKGYVRRA
The following text describes a protein:
Function:
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
Sequence:
MASVLIALGGNVGDVRATFGKAIAHICGMAQAALTARSSDYATPPWGDEEQDPFINACIEIETGLDPHALLFVLQKVEQKFGRTRTKERPWGPRTLDLDMIAYDDVRLQKPDLTLPHPRLFERAFVLVPLAEIAPDRVISGIRVRDGLSSISTQGIERLPDTG
The following text describes a protein:
Function:
Sodium-phosphate symporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSSKEGKVAVDLTAEIVGRWKETYQWIPIFGAFATVAMAFSAGANNLTAPFSTPVGSGALTLLKASIIACLIYVPGAAFTSKSTVDSLFSDFLKESQPDAGFLMWSLVVALITAAIWLAVATYWELPVSSQQSIQSALLGTILVTEGFGYIPLWNKSENHNFNGGGLLWISLEWTVAPLIACLCSYIFFKLLRAFLLRSEDAEKRILIFLPIDYGISTGLLCLFVIFQINGNIIFINTWLSIVAVLVATLVGAILSLVVIVSLTIKKSNDIPNCKSNKKSRSIDHQCIEIQDKTSSIKDDEKNHEDIEEMLRDFMQTRVLETVYEEEERSWDSPLPDKIHDSQPQIQDFQQTQSVSRKSSTDQLTQLKQLLESTPNRFVQTRNFQRIEKRTLTSDASTYIRKFAISIIRPVIEYDRRTLVRHALAEKYDEMEDFFSFPHLLASCIFALQFSIEVAAIASPYAAILDVFDHRIKYLRNGEDVEYVHVKWWFRASTGLVAAMGFFLCGWRLTRCLGGKLTYMSNSRGLASQLSSVAAVMMVTRMNLPASSIHAFVGSLLGVGMVDDIRVRFPRRK
The following text describes a protein:
Function:
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.
Miscellaneous:
MISCELLANEOUS: Decreased expression of EAF1A leads to decreased levels of H4K5 acetylation in the promoter region of major flowering regulator genes, decreased FLC expression and early flowering.
Subcellular Localization:
Nucleus.
Sequence:
MHGSVSGYLLVNAEVDSMGGVIDSGGGIGVKTSPRRTAIEKAQAELRQEYDVREERRRELEFLEKGGNPLDFKFGIATSHSVQSTSLTDQQAEHFVNSEVKDSFALTASPHGDSVESSGRPGVPTISEPNTADNLLLFDSENKSVEGERNLRHPNRQNRTSESERSSKAHTNQNTKETEDSAIFRPYARRNRSKISRDPARSSSTDLVQNRGGLATSISIRRGSVEGKGCIPEAANQKDMHTTSVSCPVFANSNGNIVPKNRVSSNSLNTKVDGEPVVRESTAGSKTSLLKDEADISYSKSSAYLPVGESGLAGEKAQLVSTGGSPKAATIAGQKNSSTQLNGLRDSTVEEESLTNRGATGTNGLESESSHANNVEVNVDNERDLYKVDKLDSDEISMQKTLRVEGLLDQTVGEMTKTKIEDETGQSTTIISECIPECEMQMKSVKIENQSHRSTAEMQTKEKSSETEKRLQDGLVVLENDSKVGSILSENPSSTLCSGIPQASVDTSSCTVGNSLLSGTDIEALKHQPSSDAVMLDTVKEDAILEEARIIQAKKKRIAELSCGTAPVEVREKSQWDFVLEEMAWLANDFAQERLWKMTAAAQICHRVALTCQLRFEERNQHRKLKKIASVLSNAILQFWSSVEAEVPGELEETSLGIVKETCQESNCLNGRRCLAAGVKEYASRFLKYNNSSISYHSAAPSTPDNMCDPEILDISMVDQLTEASLFYSVPSGAMEVYLKSIESHLTRCEKSGSSMQEEVDTSAYDTAGDIGYNVTAFDEDEGETSTYYLPGAFESSRSFNISHKKRKNLMKSHSARSYDLGDDLPYVNNTGGSNSSSLMAKRPDSNINAGSVPTRRVRTASRQRVVSPFGCATTGNLPVPSKTDASSGDTSSFQDEYSSLHGGSAVQKGTEVESSVNFEKLLPYDMAETSGRPKKKKKTHQGSAYDQTWHLDPSVHVEQKDHWKKRPENNFDMNGLYGPHSAKKQKTTKQLVENNFDMAIPHTGSIPSPAASQMSNMSNPNKSIKFIGGRDRGRKIKGLKISPGQHGSGNPWSLFEDQALVVLVHDMGPNWELISDAMNSTLKIKCIYRNPTECKDRHKILMDKTAGDGADSAEDSGNSQSYPSTLPGIPKGSARQLFQRLQGPMEEDTLKSHFEKICLIGKKLHYRKTQSVIGVSVVSFVHGIQFSSCTGAGISQSLDIPGLHVSKYSCKSWLGFPENDGRDSKQIVPVHNSQVMALSQVFPNNLNGGVLTPLDVCDASTSGQDVFSLENPGLPMLNQGTPVLPTSGAHPSTPGSSGVVLSNNLPTTSGLQSASVRDGRFNVPRGSLPLDEQHRLQQFNQTLSGRNLQQPSLSTPAAVSGSDRGHRMVPGGNAMGVSGMNRNTPMSRPGFQGMASSAMPNTGSMLSSGMVEIPNTGNIHSGGGASQGNSMIRPREAVQHMMRMQAAQGNSPGIPAFSNLSSGFTNQTTPVQAYPGHLSQQHQMSPQSHVLGNSHHPHLQSPSQATGAQQEAFAIRQRQIHQRYLQQQQQQQQFPASGSMMPHVQQPQGSSVSSSPQNSPQTQPPVSPQPLSMPPVSPSPNINAMAQQKPQKSQLALHGLGRSPQSGTSGVNNQAGKQRQRQLQQSARQHPHQRQPTQGQQLNKQLKGMGRGNMIHQNITVDQSHLNGLTMPQGNQATEKGEIAVPVRPDQQSSVGTTTSTNLQSKPFVSPLSSNHSQQLPKSFPGALPPSPQQQMQLHSDNSIQGQSSPATPCNILSTSSPSIAPAVAPSNHQHLLIHQKQRNQVQSTAQRVVQHNHLGNSELSKKSQAERMPRVPQSVTNTTQTVSMGTTKGMPQASNDLKNIKAVGSTAVPALEPPSCVASVQITASKVVNSSNTDSAGNDPVSTPNQGLAQKHGIKGVTQRQQQSLPSEEKRPKLPEKPTVQNQKHLASEEQPHLEEAQELSSSKPPDTKVE
The following text describes a protein:
Function:
Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity). Transcription regulator that restrains empty glumes growth, lemmas of the sterile florets located at the lateral side of the rice spikelet, to maintain their small size, probably by repressing lemma identity via transcription regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSSSSAAALGSDDGCSPAELRPSRYESQKRRDWQTFTQYLAAHRPPLELRRCSGAHVLEFLRYLDRFGKTRVHEPPCPSYGGRSPSAAGPVAAAAAACQCPLRQAWGSLDALVGRLRAAYDERHGRAGEPDAVAGAGAVATDSTSSSSAAAANPFAARAVRLYLRDVRDAQAMARGISYHKKKKRRGGNMNGARGGGGGGARAGVNDGDATAPPVAVTPGLPLPPLPPCLNGVPFEYCDFGSVLGGAHGAHGGHGGGGGGFYGAGVYLPFLYNTFS
The following text describes a protein:
Function:
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
Subcellular Localization:
Nucleus.
Sequence:
MSRHGAAEDGLNRLKNVYRPRYLYGDGLQEPQKTRPGQNILSAIKNCFEDPNSQAYFKKPGNIIRMDSLLSLESGSTMLDSESGEEEDTEQTTPGDEGAVLLEKAATPTGAVRNLAKSLDRTYILEQSAVQNPASPTITLPTKKRLSFKNFTEPEANNKRMRMSEKDLICSTDEKESEIQHHVMAVEKKNFASPHKKRTTLTGFPEKRPSKVVPYPQNSLFQQQDEIEHDNEDEFMIDEVDSFVVNSWISNPKKAKSDLKGSMSAHSKKSQQVNEEAKNIQRDICDRARVVNKELSSEKFSSYGHNTNMSPKNKGGTGKKNLGQRLCENDLDYLSSEVQNLQQTLSNSQIVINTQSASEAALARIRGTSVYIARELQSPNLKQKHQPESSEEVQLPKTKVTSTSKSVYIQEIDMGGPFQKQKKQPDPQNMELIQSLKDAADMEEGKRYANADNPKEDQAEACLPEKSGSLGKSNVRTGLSTGKKSLTKKTMQSSAFKQNAHKPEVLENTGETEGFATLGNSKILEKPNHLLEIRNPRSPVYSMFLQAATQGHATRYSVVQEAPIFNIPHQGEEDDNDFVFDEAALLDCEPLISIPRRGKPLPSKKIIWSERDTGSRVCTDSMQNDTEKDQNNVGANEQNQQATPKEKSTRKNPALSDKNFTLNKEKPLDKVDNSIKLSTQKGKKSKSACVDGPSELDEHDNNALSDEPHLKKTSSKKQILSKTNKGKPVKKAQKKKQTRSKGKPTPLNRNKNNGGQEAINTGTGFSDEACTPDGIQKQSKSARISIYSKVVSPARRNIFSSDENENPHVTNLQIASSPYKRVKKKDIDNFEFPETLSSQDLKQAHTPNQRLQASAAEKVTSAICDQLETGRTQRISRPPSQWWIVSPSHTNKTVLVEPELPSKSLQKENKNKSKKKKGTKKEKIPDANDDKGITVTIPNKRKTPLKKGNKKQLEDISSADEGCAEMPVSAADVKNSASLPNVRDLEMQDSEMQRGFQKMLKPIIKKNKRRSKKLISSEESEKELAELSEDDGYLDNECSVPQAQESRMRCQKLIKPDCQNQNFIVSGATLLDASDESPYLIDDEPENTSESGSDCATSSITVGKTLVSPRKVAQLEEIKNTPQLLSSDSEGNNKPEPRSQRKSREDLYTSTVGSGPTVPRIVRLTTANEKPITYEPYTSSSGSDNEYEYGTQLHKIIPPSKTPNVRRSKRTRVKPLAYWKGERVNYKIRPSGGFLVEGVVPPAEVEPPRKAVAKRRIYNKQKGHIPTYVEPLTEDYVEPAKVLDADTGTITTIDCVRTSENCLYHDPDQPISICKSIRNSAFSTGKLKIGPFQEKGLQFVCMDTIVFYIMTGSVQLTLHLSTYNLKTGDFFYIPPGNMYNVKNLLNEDAVLIFTQIKGGS
The following text describes a protein:
Function:
Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing (By similarity).
Subcellular Localization:
Nucleus. Nucleus speckle.
Sequence:
RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSRSRSRSRSKDEYEKSRSRSRSRSRSP
The following text describes a protein:
Function:
Acetylates the N-terminal alanine of ribosomal protein bS18.
Subcellular Localization:
Cytoplasm.
Sequence:
MNIRRAVCADCEELAALDAVCNPSAWTQRQFESALVSPSEQVFLAEKDGGIAAFIVWQNLPDESELHLIATAPECRRQGIASALLEYWFTHLPEDTQRLLLEVRAGNTAAQALYTAHGFSITGRRKNYYRTADGKTEDAVLMEKIC
The following text describes a protein:
Function:
Involved in phagocytosis and cell motility. Binds to actin filaments and protects them against depolymerization.
Subcellular Localization:
Cytoplasm. Cell projection. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Accumulates in cell surface projections during movement, phagocytosis and pinocytosis. Detected at the leading edge of the cell during chemotaxis.
Domain:
Seems to consist of two repeat of a full-length coronin.
Sequence:
MFKVSKYRHTVGKIDKRELWYPDVNTTGNSSASTFIKANSKWVALNWQSNTGTIGLIPLKSFGKRKGETFLIHAHSSGVIDFEFNPFNEHQLVTASDDSTIKVWNIDEAIRSGATSLSSASIVCSGHSKSVECIAFNPVANNILASCSADKTLKIWDLSNGEEKYSWNFEQGSLTSLSWNYDGSLLVATGKDLKNRIIDARTGESIQVGDGNQGVKASRVVWLGNLNHFLTAGFSKMRERQLVLWSSQDLSKPIKSITLDSSTGIISPIYDQDAQLLFISGSGDSSVRVFDMNTQFTKDPAFTELSPVPSDTPSKGICALPKRALDVMEVEIDRIFKATPNNIIPITFNMSRKSKSTFADDLFPNTASTKPSLSSIDWLSGENKQPILVSLNPSDNQINNDLDDLQLNDNEPVKKSTFFIDDNTNDNSNVVEQSKSEPEQQQQEEKKISSSSSSSSPTNSSSNVINSTPSSPIVNDNIQRTGIVPKVVRSSKYRHISGSAHQKSQFYTNLKINGSTSNTCIAVNSEYVAVPMVGIGGPLAVIPLADKGRQIQVPCIEIGSQLCDYDLSQHNTSLVATGSEDSHVKVFKIPTGGIPKTTANKSNNYTTTEADFVGHNRKVISVNFHPTAENVLITSGGDMVVKLWDLNEGGAGEKLSFANVHTDMITSVDVNWTGDKILTSSKDKKMRIFDPRTNKGGLASETVTHSGSKGGKAVWLGQTGNIFSVGFNKSSEREYQLWDSRNLQSGTPLASDKLDHLSGVITPFYDEDSGVIYLAGKGDSSIRMFEINDQEPYVHYLTQFSAGTPQVGVAKFAKKTSMDVKKCEIARFYRSTDSTIEPLSMTVPRNRQEFFQDDIYPDTRQTCTPVMTSEEWFDGCIREPEFVSMKPSDMINLSDAPPPPKKEDKFVVSQEVDNTPSRDQVTNSLLSRVSNQNASSNWEQIEKLKHNFTDYDNGDISDSEWD
The following text describes a protein:
Function:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
Subcellular Localization:
Nucleus.
Sequence:
AALNNLTEHLEAFVDVTRSPTHHAESLKAIATSLEKSVLSINQLVVEMDMYLTTTDDVVRARGILLLAEMLDYLKSKPLDNAVVNSLVGFFTAKLAEWRSVRGALTGCLALIRRKGVAGVVTAVDAEAVAKSMAQSVQVQSLALYDRKLCFELLECLLEEYPEAMINLGDLMVYATCEAIDGEKDPPCLMVAFHVVELLARLFPSPSGPVASEASDLFEFISCYFPLHYTHTKGDEASIPREDLSRGLSLAISSTPFFEPYAIPLLLEKFSSSLPVAKVDSLICLKDCAVNYGVNRMKKHYEGIWSAIKDALYASTGTDLSFGLESLTSPGFEMGEIHREAVNLLQRLVKQDISFLGLVADDIRVKMIFDTISRYSRYEEMLDTSKLEVLVVSQILSVSARASVESCNTIFETFFVRLMNTLGIVEKTSSGDLVHNENSTVSTRLYHGGLHLCIELLTASKDLIPSSEEDSSTPESAQQSWCSIVNRFSVSLIEAFTSAVQSSNDDCSADAYLGVKGLLAMGMFRGGFSPVSRSEFEKILTTLTSIITDNSAKTVKWELALKALVCMGSFIDQYHESEKAMSYMGIVVENLVSLVRSSHCSLPHPMILEAISEVCSTRPTYVEKMVQGFEEAFCSSFSDFCVNGNFKSIENCSQLLECVTNKLLPRLTEIDGLEKSLVNFAISMWNQIESSVVFSYDFNGREFVEAAMKTMRQIVGVASVDSQNSIIQKAYNVISSGTLPAMESIPLTFAALEGLQRDLSTRDELILSLFASVIIGASPMASIPDVKSLIKLFMVSSLKGYISAAQALGSMVNKLGTGLEEACDTIFHESSASGNNTSSVDSSKSIGGSEALLAKICLGFYGSLDLQTRAITGLAWIGKGLLMRGDKRVNEIAHVLVECLKSTNSSGNALHPSALKHAADAFLTLMSDSEVCLNRKFHAVIRPLYKQRFFSITVPILESLIVNSQTPLSRTMLHVALAHVISNVPVTVILDNTKKLLPMILEGLSVLSVDSEHKETLFSLLLVLSGTLTDIKGQQSVSDNAHRIIECLVKLTSYPHLMVVRETAIQCLATLLELPHRRIYPFRREVLQAVTKALDDPKRRVREEAIKCRQAWTSISSRSTPF
The following text describes a protein:
Function:
Component of the U3 small nucleolar ribonucleoprotein. Required for the early cleavages at sites A0, A1 and A2 of the pre-ribosomal RNA. Participates in ribosome biogenesis.
Miscellaneous:
MISCELLANEOUS: Present with 1430 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSELNALLKDINGSLTATSESLERLSGIYSNSATDEIPESNQLHEHLFYDAKKPAEKVSLLSLKNGSMLGYINSLLMLIGNRLDDECKDPSAMDARERSIQHRVVLERGVKPLEKKLAYQLDKLTRAYVKMEKEYKDAEKRALEKSTLVNHSGNDDSEDDESSEDEIAYRPNTSGIINTNKKSSAYRVEETAKQENGEENDDNETGVYKPPKITAVLPPQQTHFEDRFDAREHKDRSNKSRMQAMEEYIRESSDQPDWSASIGADIVNHGRGGIKSLRDTEKERRVTSFEEDNFTRLNITNKAEKRKQKQRERNARMNVIGGEDFGIFSSKRKLEDSTSRRGAKKTRSAWDRAQRRL
The following text describes a protein:
Function:
Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation (By similarity).
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Nucleus. Cytoplasm. Note=Predominantly localized to the plasma membrane through the binding to phosphatidylinositol 3-phosphate. In C2C12 cells, with the absence of growth factor, it is found in the nucleus. It rapidly translocates to the plasma membrane after insulin stimulation. In response to TNF, it translocates from the plasma membrane to the cytoplasm and then to the nucleus accompanied by cleavage by caspase-3. However, the subcellular location is highly dependent of the cell type, and this explains why it is found exclusively at the plasma membrane, in some type of cells.
Sequence:
MKKSGSGKRGPPDGNHQSVAPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYVSEKEVKDEKNSQEVFDLSDYEKCEELRKSKSRSKKNHSKFTLARCRQPGTTAPNLIFLAVSPEEKESWINALSSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPASCAESFRVDLDKSVAQLAGSRRRADSDRIRPSSHRASSLSRPWERPDKGAPYTPQALKKLPSTEKSRCASLEEILSQRDTAPAHPLHLQAEESPAPVPSQPGQLSRIQDLVARKLEKTQELLAEVQGLGDGKWKAKDPPRSPPDSQSEQLLLETERLLGEASSNWSQAKRVLQEVRELRDLYRQMDLQTPDSHLRQTSQHSQYRKSLM