lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
3'-5' exonuclease.
Sequence:
MKQKRYIVVDLETTGNQASREDRIIQFAACFVESGKRLETYTTFLNPEKPIPAFIQELTGISPKDVKNAPLFEDVAPIIANLLEDTIFVAHNVSFDWTFLEREMTRAGISLGKMKKLDTVELARIMYPGIDSYKLQDLSDEFNLGHDKPHRADSDAEVTADLLLLLLEKLENLPLPVIRQMTTISGSLKSYLPELLFEIEMRKERENKPLNPNFVEHRGIVIRKKEVEKPTYSRADLLEFPETDEAKMALFKKAGAPLYARSGQFEMMNLVFQAMKSGKHALIEAGTGIGKSLGYFLPAIYQAKQAELPVVISTYTNLLQAQLFEKDVPLLTKLTGFKVKASLLKGRDHYLNLFKFEQLLQEVDTQYDVVVTKLKLLVWLTETTTGDIDEVNLSSGGELFWNRMKHTGWFLSEKHDPWLAHDFYKFNIKQAKNADLVIVNHALLLNDHFSGRETLPKYAFAVIDEAHHFADSARMQGSFVLSYRKLKYFLNQLGSLEKYSLLTRLAMAFPEADSLYDLDIAAMKLSDAVEELFVLLKMQLNFARKNLQEVVLVENSEKDAWNDKVYYAAEKVLYLLKESEKNMETLLEQGKLEENELGEAESAFLEEMYAFLLDWKNMAKQLEQMLHKKSPILTIYLQADKNHSISSIRLKAVLMEVEPTLGKEFFAKKESVIMTSATLTVKGKFDYLRKSLGLEEEQIMEKCIPSPFDYKENARVMIPDDMPPIKDTPIERYTAELAKYIRHIAVKTNGRMLVLFTASDMLQKTYYHMKNEKSLEEYVVLAQGVSAGSAARLTKQFQMFDKAILLGTTSFWEGIDIPGEDLSCLVIVRLPFAPMDDPYTKAQISLRKERGENAFQTYSLPEAVLRFKQGFGRLIRRESDRGIVFVFDNRVDTTKFGKAFLESIPSAPILKGKQADLLEEVSEFFKEG
The following text describes a protein:
Function:
Endonuclease that cleaves polypeptidyl-tRNAs downstream of the ribosome-associated quality control (RQC) pathway to release incompletely synthesized polypeptides for degradation. The RQC pathway disassembles aberrantly stalled translation complexes to recycle or degrade the constituent parts. Vms1 acts downstream disassembly of stalled ribosomes and specifically cleaves off the terminal 3'-CCA nucleotides universal to all tRNAs from polypeptidyl-tRNAs, releasing (1) ubiquitinated polypeptides from 60S ribosomal subunit for degradation by the ERAD pathway and (2) cleaved tRNAs for recycling. Component of an evolutionarily conserved system for ubiquitin-mediated mitochondria-associated protein degradation (MAD), which is necessary to maintain mitochondrial, cellular, and organismal viability.
Subcellular Localization:
Cytoplasm. Mitochondrion. Endoplasmic reticulum membrane; Peripheral membrane protein.
Domain:
The VLRF1 domain mediates binding to the 60S ribosomal subunit.
Sequence:
MGDISKHNIFSLPEDILAKLELREEYSVEEKTDSANLSNQGDIVDSTQKNISSCVNCQIDNLHTLDERKSHIKSDWHRFNTKRKITKLPPVSQDEFESIIEDLPESLSGSESETNSESEEDNFQIEKAFKQSLNIGKVDSADENNNQRTNSPLTWFQLSNASAEVPTYIGVYKHMFSGNNHITKDLLVQQQNHNRQKPLQLAMFMVGGGHFAAMIASNEFNPRDPHVPKVLAQKTIHRYTTRRKQGGSQGAADNTKGNIHSAGSGLRRYNEQALIKDIQQVFKDWGKLLETCDLIFVRAIGSSNRSIFFSQPGALISPKDPKLRVFPFTTKRATHSELLRCYKELVTPKISHVDSISIKAQEEERKRQAEIEKEIRQSRLQEEERKKKKLAKYTEVIISNLKASNIEAFLEYLRSNDLSINFQFYPKNVHLHTSTPLHYAVTQKNAKLVAKLLRNGADPAMLNGNGKTPFEISTGNKEVKDEFLIARHELGESFFDWEAAKVGAPQSREQIQKQRQKAKTKLENQRRDKERQEELRRKEAMQKIEEQSKRDYDKLHGEGHSLGINNVRKVDELQSLSPEMRMRIEREKRAAAAMKRMQTK
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression.
Subcellular Localization:
Nucleus.
Domain:
Interactions between auxin response factors (ARFs) and Aux/IAA proteins occur through their C-terminal dimerization domains III and IV.
Sequence:
MESGNVVNTQPELSGIIDGSKSYMYEQLWKLCAGPLCDIPKLGEKVYYFPQGHIELVEASTREELNELQPICDFPSKLQCRVIAIQLKVENNSDETYAEITLMPDTTQVVIPTQNQNQFRPLVNSFTKVLTASDTSVHGGFSVPKKHAIECLPPLDMSQPLPTQEILAIDLHGNQWRFRHIYRGTAQRHLLTIGWNAFTTSKKLVEGDVIVFVRGETGELRVGIRRAGHQQGNIPSSIVSIESMRHGIIASAKHAFDNQCMFIVVYKPRSSQFIVSYDKFLDVVNNKFNVGSRFTMRFEGDDFSERRSFGTIIGVSDFSPHWKCSEWRSLEVQWDEFASFPRPNQVSPWDIEHLTPWSNVSRSSFLKNKRSREVNEIGSSSSHLLPPTLTQGQEIGQQSMATPMNISLRYRDITEDAMTPSRLLMSYPVQPMAKLNYNNVVTPIEENITTNAVASFRLFGVSLATPSVIKDPVEQIGLEISRLTQEKKFGQSQILRSPTEIQSKQFSSTRTCTKVQMQGVTIGRAVDLSVLNGYDQLILELEKLFDLKGQLQARNQWEIAFTNNEEDKMLVGEDPWPEFCNMVKKIFIYSKEEVKNLKSRKSLSS
The following text describes a protein:
Function:
Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with DDX1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation.
Sequence:
KQTGSRTEGAVMAQKEGDVRDYNLTEEQKAIKANYPPVNRNYEYLDHTADVQLHTWGDTLEEAFEQCAMAISGYMIDTRTVEPLQTIEVETQEVSTFLFHFLDEWLYKSNADEFFIPWEVKVICIDQRHFQLQSIGWTEEFSLSNHPQGTEVKVITYSAMQVYNKENPEVFVIIDI
The following text describes a protein:
Function:
Confers broad-spectrum resistance to pathogens.
Subcellular Localization:
Secreted.
Sequence:
MAKFCTTITLILVALVLFADFEAPTIVKAELCKRESETWSGRCVNDYQCRDHCINNDRGNDGYCAGGYPWYRSCFCFFSC
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MPAGHRPWALPRAAAGPLRRSATRIRATTPAGHRPRALPRAAAGPLRRAAVRICAATPTGHCPWALPPAAAGPLRRSAPRIRAATPAGHRPRALPRAAAAQPIRVVLCFSCFCILKMGGNTRGGGHYEALKSYNLGKTLRAGTFGKVMIADHKLTGHKVAIKILNRRKMKTTEMEEKANREIKILRLFIDFIHPHIIRIYEVIETPTDIFVVMEYCQNGDLVDYIVEKRRLQEDEARRIFQQVISGELYAGPEVDVWSCGVILYALLCGAVPFDDDNIPKLFNKIKEIDEDTLQDVANLGYDKDHVCESLCNRL
The following text describes a protein:
Function:
Negatively modulates the activity of sigma-E (RpoE) by stabilizing RseA under non-stress conditions. Although not essential for association of sigma-E with Rsea it increases their affinity 2- to 3-fold. When bound to RseA it prevents proteolysis by DegS, which is probably relieved by lipopolysaccharide binding (LPS) (By similarity).
Subcellular Localization:
Periplasm. Note=Partially associates with the inner membrane via RseA.
Sequence:
MKKIPLKFTALSLSLLLSSIASAEELSAKQSLDKMTQALDNLNYEIAFVQTTPANMDSFRYRHIKQDNKTYAQLVTLDGRQQEIIQRDNLVSYFQPNAQAFTLNSGNIVDAMPAVVRANFDKLSSDYDFVKLGKDRVAGRFADTIRIVPKDDFRYQYLVFIDEENGLLLRSDMLDREGKLLDQFRVVTLYIDDRLRGLTDYINKVSLPPLLKESKNEQSSDITWSAGWLPQGFSLIRYTQEILENEIIDSALYSDGLFTFTLFVSNVGSNDLPENTWKQGAYTIYSEVIGGKEITFIGQLPISTAKRIVQEVKFR
The following text describes a protein:
Function:
Required for nuclear membrane fusion during karyogamy.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Sequence:
MKFHPTRPFGLYFEFFIIISFFFTSESTGDVESFMKYSNVAFSEGLAGFDSLAHVYQALLKKSTCYQEVAATLISKCSLLNTELTIDNRIHSAIQMTLCDFERSQILAPSECVRGSQSECVSKLESTSTWWLSFTSHFHDVNHLCRLANLEMQKELSIEVNMNVTLVQKQFLEMVILHLRNFESVTDKMNQRIDKFDGKFNSVIENSFKDINFRVNQEIMGLVELQNHQQEGMVQQKEILSTIKQLKSEIFDINSFFANFIEESAGYSNSLIEKLNEKFTSENAIALSAIGKYTSEFSAFMEKRIKNLITTTEDSLQQSVQSNIDFVNSGFQPLYDLTIQLKEELQSLKRLSSEQQNLQHEQILQWKSDFLNVSKDHLKVLQQLRPLIDIVEKFMNVYFKGLSNIISSFAFIGFTLFATLSSLFFKVLKIHRRPIIVFGSLSIIFIHIYCFKITSWVNLYGWITCTIARTLSFIKLNIRTFYLTAFLCALLNFLRYLKYRNSKKDTELSLFLPAPEECNIYHNEHIQVQEDNYLCPIENSLIDLFGSENNKEKLGKQENVRFAFLNSESLEQSPWWD
The following text describes a protein:
Function:
Carboxypeptidase that catalyzes the release of hydrophobic and acidic C-terminal amino acids.
Subcellular Localization:
Secreted.
Sequence:
AFDLNDFNTLEDTYDQMNVFQLSEAGLTHEGRDMKSWIDSLTHCRSHLDEDVFMFKRNEPDSGSACVGTDLNRSSNNPCSDTYGGSGPASALETRHSYSQQYEDELNQRQRYEPSGTTVNNLLNKDAGSIYSYTPELR
The following text describes a protein:
Function:
May function in nuclear protein import.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDPIIQTIQLFQHTLHHDANVIKAAEAQLQQIKVTDGYSRILLKILASNEVDISIRQGVSIFLKNMIITKWRGAEDESPITQEDAEFIKENLIDLLVHSHHLVQNQIEAMIEIIANRDFPEKWTSLLPKSIQYINTQDVKLILAGLTSIQLGIKRFRYVTMGDKKKELLYTIVNEIFPLLLQILEFLSQHQTIESALMQKKVIKIFGYAIHFEIPDLLIQPEVFNKWLSQFVRIIQRPITPQENVKHADDCRKNQWWLLKRTTAKLLNLLFRKSATSVRSTDHSSVKALNKLFMPVYSVEVMKVFYEQLSTLEQLYKGVHYERYQQKLIEYFSFAIKYGVTYVAMKPWLSTLIQQVLFPIICFNDRDAELWECDPNEFLRSQFESSMTFATARIEVLNFIIDVVGKRGRANLDMIMGFCIQSLNKYNAATNASEKNPREKDGVLVIISVLSAYLKNISFYKSNLEQMLLLHVFPELSSPHGFLKARACSLFSEFYNIEFTDPVYFSNALKLILGLMSDNDLPVRVKAGTSICNLVRANQGVDELRPILPQLLDKIFSLLSEAESEDLVIAIESIIQRFKHEIAPYAVNLCKNLSEQFLRLLELEESDESGESGFASQECLGVYCTLLRALKDIPDVFNSLEQQIVPILQKLFTSDHMMYLDEALRILTFVTYYPKSISPLVWSLFPQIMNLFDECACDFASSYVNPLDNYISYGTEYFLSNQQYIEMVFNMYKKMVGDINQQPVDAGDCCKIMESLIQRAKGRIDYMIVPVLELACGRLLNTDKNNQKSKEFTVYLLEIIANCIYYNPLISTQYLESKNLVEPIFGLWFNRIKHFQRFYDKKISVLAFSSLLTLNPSPNFVKFGTSLILEKMLQFTKDMLSIEKELDKQEAEREQKIKDGTLKPEEEEFIDENDEEDYFDNHKFEFEFTEIPDNQDCQHDDEGEVFLDDIEKATEYFENGGDLGEDEGDNFDDQNDDDDQDSEEDLFEDEDTPDFETPIDEVDGFEFMINSIQNFFQINPTCIQQISEKQQEKIKKYVASAPARKEKLRLEKEKEEKLKQQQQKK
The following text describes a protein:
Function:
Binds double-stranded RNA.
Sequence:
MPTNEDFQSVSNCYVFKSRLQEYAQKAGLPTPVYETIKEGPSHEPSFRSTVIVNDVRYDSLPGFFNRKAAEQSAAEVALVELIKSNLVNQSITQPVCFFQHETGLCKNLLQEYAQKMNYAMPMYQCKKDETPGRASVFSCTVDIGGILYIGGAAKTKKEAEIKAARTALLAIQSSASQASQDQVGHPQLTVLPCRKRATESVAIADENSNPPKPKKARFKRKSSKRKPSRDKMGQIHTENLGIGANINHEVETHASVNGESGVLEKKSETFTSEAANNFENGVSVNYQEKETLAGESSLAVNSQEGIFENGKSTELYSKENNLVTVVTELSSVSNGGIPETGVEVNKQQYNGEMVSDHCVVGG
The following text describes a protein:
Function:
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTLTALLALLLSYLIGAIPAAAWLARARGVDIRKVGSGNSGATNVLRSLGKGPALLVASFDILKGVLAVLLARALGLSAEWAALCGVLAVIGHNFSPFLAFRGGKGVATSFGVIAILDPVLGLTTFVLAIACMWLTRFVSAGSIMGAFIAGALVLVLPRPTWDRAAVLFLAALLVWQHRENIRKLQAGTERRLGEKVS
The following text describes a protein:
Function:
D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
Sequence:
MTDTNPENVNNSKITIICSAPDLASQNIKKHLLALREWKPLELPENSGFSAVLESADGKFRLVDIEEIHVFQDGLDKKLEAAGLPAELIIFASKHRSKEEVKSLTVHCTGNSSNEARLGGHPKELAVSSPPAMKSILMEMKRLAKVKGLDYDVTLEVTHHGPTELNVPSLYAEIGSTEGQWEEPVPGEIVARAILTVSLEKVPTAVGFGGGHYAMRQTGLLLETAISFGHNFPKYQLEFVDEALIRQAVEKSNAEFAYFDRKSMKSADRKRISQILEKLGLKVLKESEIREKYGREE
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MSSNSNLTTLRRSVEQLKLEASVERIKVSQAAADLQEYCLQNASKDALLVGLPAASNPFREPRSCTLL
The following text describes a protein:
Function:
Inhibits trypsin (IC(50)=1.25 uM) but not chymotrypsin or papain. Has antibacterial activity against S.enterica ATCC 10708 (MIC=5 ug/ml) and S.aureus ATCC 25923 (MIC=5 ug/ml) but not against B.subtilis ATCC 6633 or P.aeruginosa ATCC 25619. Has no hemolytic activity against human erythrocytes. Is not toxic to mice.
Miscellaneous:
MISCELLANEOUS: The monomer may consist of two smaller chains which are linked by at least one disulfide bond; MISCELLANEOUS: On the 2D-gel the determined pI of this protein is: 6.6.
Sequence:
VRDICKKEAERQDLSSCENYITQRRGY
The following text describes a protein:
Function:
Central component in the thioredoxin system. Reduces thioredoxins 1 and 2.
Miscellaneous:
MISCELLANEOUS: The active site is a redox-active disulfide bond; MISCELLANEOUS: Present with 292000 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Mitochondrion intermembrane space.
Sequence:
MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKYLTSLE
The following text describes a protein:
Function:
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Acts as a negative regulator of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MAAPGPLPAAALSPGAPTPRELMHGVAGVTSRAGRDREAGSVLPAGNRGARKASRRSSSRSMSRDNKFSKKDCLSIRNVVASIQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRRETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFTA
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MGEMERPPQLDYAQNWDAAMDLTLRRFVYGSLSGAASALLLFRSPTTRWAAVAFGAGAGIGSACTDSFKLFPDTVGATFPFSLMPSRSVARDVQSRHADTPEPKHVQELLIQEAQA
The following text describes a protein:
Function:
Plays a role in vesicular protein sorting.
Subcellular Localization:
Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Prevacuolar compartment membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MITNGVEDEEKWLAAGIAGLQQNAFYMHRALDSNNLKDALKYSAQMLSELRTSKLSPHKYYELYMRAFDELRKLEIFFREETNRGCSIVELYELVQHAGNILPRLYLLCTVGSVYIKSKEAPAKDILKDLVEMCRSIQHPLRGLFLRSYLSQVSRDKLPDIGSEYEGDADTVMDAVEFVLQNFTEMNKLWVRMQHQGHAREKEKREKERSELRDLVGKNLHVLGQIEGIDLDLYKDMVLPRVLEQVVNCKDEIAQGYLMDCIIQVFPDEYHLQTLETLLGACPQFQPSVDIKTVLARLMERLSNYAALSAEVLPEFFQVEAFAKLNSAIGKVIEAQEDMPIAGVVTLYSSLLTFSLHVHPDRLDYVDQILGACVQKLSGKGKLKDNKATKQIVALLSAPLEKYKDIDTALKLSNYPRLMENLDDSTSKEMANVLVQNILKNKTCISTAEKVEALFELMKALIRDLDEGVDDELDEDDFQEEQNSVAQLIQMLHNDDPEEMLKIICAVKKHILTGGPKRLPFTVPPLIFNSLKFVRRLHSHDENVPEEESSAMPKKFFQILNQIIEALSIVPVPELALKLYLECAEAANDSDIEPVAYEFFTQAYILYEEEISDSKAQVTAIHLIIGTLQRMHIFGVENRDTLTHKATGYSAKLLKKPDQCRAVYACSHLFWVDDQDNIKDGERVLLCLKRALRIANAAQQMSNATRGSSGSVLLFIEILNKYLYFFEKGVSQINVASVQSLIELITTEMQSENTTADPAADAFFASTLRYIQFQKDKGGAVGEKFESINS
The following text describes a protein:
Function:
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTETILAAQIEVGEHHTATWLGMTVNTDTVLSTAIAGLIVIALAFYLRAKVTSTDVPGGVQLFFEAITIQMRNQVESAIGMRIAPFVLPLAVTIFVFILISNWLAVLPVQYTDKHGHTTELLKSAAADINYVLALALFVFVCYHTAGIWRRGIVGHPIKLLKGHVTLLAPINLVEEVAKPISLSLRLFGNIFAGGILVALIALFPPYIMWAPNAIWKAFDLFVGAIQAFIFALLTILYFSQAMELEEEHH
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MFHLITIEDKVRIAPSQFNNEVQTIEDEIEKKYTSKVVLNAGLFVALYDILGTGDSYVHSGDGGAHLMVRFRMVVFKPFKGEVLEGVIKKSSRQSIQISLGFFHEIYLNPIELPNPSNYNQEEGLWYWEWNENQLFFEDGGRVRFKIDQVEFNPEISQPAPSPKNVNTEAMDSYSLREYKEKQIENENLLKQVKSPLILKVSMREAGLGMVSWWTNQSAGDDDENEEDGGENQDDEVAEDDGGEEPTIEEDE
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MIMHTPIMMTTLISLTLPIFATLTNPYKKRSYPDYVKTTVMYAFITSLPSTTLFILSNQETTIWSWHWMTTQTLDLTLS
The following text describes a protein:
Function:
May be involved in lipid metabolism.
Miscellaneous:
MISCELLANEOUS: Present with 2550 molecules/cell in log phase SD medium.
Subcellular Localization:
Lipid droplet.
Sequence:
MNSGGEEPTIKPNVFNITQLLNSNGEKPGIACIFLSKFDMKKGNIIIWSKSINGAAIDLSNIEFKSLPAGIHEQTDDVVNFVVPKELDVCQTAKTTTYDYGIAYFKQNSFDIIENDNRIDRSKVQMFSLGVIIDVQNASSDSKKHFYKEIYHAYAANRYSSYLESLLGQWIRQRDLDKFDIFEKFFDENNQGHMAENSVEVFEHSPKERRHLVEYLPYWTRKLGPLIFPLWKASLLQSRILILVPQGESFELCNSLAYCVFLISMLPKNLIGNHVSDEYIKPIFTVSTSDIPFLESFKKGNGYVATTSEEILLYKPEIYDIVVKLTSSSTIEESPEKEVEILTASGEQNKATPLDLEVYEKLILGELQEDASTNATCRHHEVTEPISWLQFLIDGFFLLTTAGYLVAPYHLANNFKIPRHVSGPEPNNSEIQIAENLVRYFHRRTSNLYNDLKDVIQKSENIDSEQPITIAASFLTKLNLDCFSKQDHQFVKDIALKWFQRSIDISNLPECLGNLC
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MQHLLDPIILNTMNKDKKQMTEKILNHALGIIFLLTGEEYIIVKKNYPHSSIQLLTGEVPIKCGDVAVYFSMEEWEYIEGHKKHYTDVVTDNQKSSEVPAQEHPGLCDRNQNMAATNDVDKMEKHGNAVQQDPVGSDTGPANTQNKAPENVLIAKEEKKKTEDLNRNQHGKVHSVFYTGDSHNGVCTKHEMRPLKKNLLGASHNAVCTSDERMCMKRNILGDTHNALCTSDERMCMKRNILGDTHNAICTSDERMCMKINKFGDSYSSMNTSEAVMRVKSKILNPRSALGTSEEVMHRKNNILGGYTNAVCKSEEVMHTKRDIMVSSHNATHTTDKMVFGNTRFCTEFQGRNYGVPHNEQKPFGKVILTPFSVPCPRGYKTQDLREQFVAGSNDGVSYIKSMVNDHQAKLKDEKPYKYEVQRQLSPKCRDSEEKPHKCNVCGKQFPTLSKASSHSRIHNKPFVCPECGKGFPFRSNLNKHLRTHTKVTQHACPECGKYFDKRTLLEKHFRTHTQEKPYVCPECGRCFSQRSCMETHYRIHTKEKPYSCRECGKCFAQRGHRNMHQRIHTGEKPFPCPECGKCFTQRIHLDVHYRVHSGERPYPCPECGKSFTTKANMDAHLKTHALLNPCDP
The following text describes a protein:
Function:
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
Subcellular Localization:
Nucleus.
Sequence:
MQSRTLAPEMHSVVTTAQAWLLSSWHVRVPFAWLEACVQWLQEEAGEAAHLSQQQVNQLVLDQWLLTDLRDLDYPVLPEGLAQAQKTQLNGIFCVQVDSFLDISQPAYGQLQKWRGTDCGNDEVSAVTQATQRPWEAKTTRMMLLQVTDGVQSLEAMEYQPIPALSATLRPGAKLQLQGQMVCRLGVLLLGPSNVKILGGEVEELVDRNNMGKVLCRTLGIPEDQQQEGEEAPPPAQQGNQEMEDIDLNDAELLASLEAQNEVGFVGPVRDSGYETLQESSSVSSSVRSQFSSRSAASNRTRRDGLTPSHTNGSVQDGQQQRGGFSNFLPPSVIHQDIHEHNAIEEDFPDEDFDDLPLDELDNVMFEEAENVPNTSSGFGSRTGRTKPVIQIRDHQGSSREASEPLTLPTSSSSSSSSVLNTKSLLMDEDMDCFIPEVQTSGVETGTSGGLAQISAGGPAKDKDSNTNTTRTPGFTSRLFSKSAASETSTPQGKPHNLTALTLTSPPFVYLCMLKDLLSKPQSHPVEIQVKAFIVTLLGKLGCTNGAWSVFATISDGTGYLDVALSNDVLTGLLGFSVAEKGALKRDPARRGELEAGMRRCQEALVDMCCIMTIVLEQDGGKAVVAKADPISETVLQQLEQRVKDRRK
The following text describes a protein:
Function:
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MKRAHKAPKASHKAHKRQKVEKKPRPEINVPKRKIRLDDLGWNQVSMPDRLEDFEGFYGLEEIEDVHVVKDAVTGNLSFETTKTDEQIEQDIEKAWQREEEEAKFLEKITFGGEPKNGEDVVEEETAPVEDTVEATQDEDAASWGGFSDDDVAQNGDEQSEDVQMVEEDAPPTPNVVLSTTKADGDGEAEPKKMNKRERAAEKKRIAALAKKTKKPDDDEASEGKTFGPGAFDILANRADDEDDEVDVSAWEELELSTKILESLAKLKFSKPTTIQASTIPEIMAGRDVIGKASTGSGKTLAFGIPIIESYLASKSKSKDVKDKTPLALIIAPTRELAHQITAHLTALCAKGAFEAPLIASVTGGLAVQKQRRQLEKADIIVGTPGRLWEVISTGHGLLEKVKQIRFLVVDEADRLLSQGNYKELGEILKILEKDAPAEGEAEAEETTEVERQTLVFSATFQKGLQQKLAGKAKGGSDNLMSKQQSMEYLLKKINFREEKPKFIDANPSSQMASKLKEGLIECAGTEKDLYLYSLLMFYPKKRALIFTNSISAVRRLTPFLQNLALPALPLHSSMAQKARLRSIERFKERPGSILVATDVAARGLDIPKVELVIHYHLPRAADTYVHRSGRTARAEASGSSILICAPEEVGGVRRLIAKVHARADEAPKSKKTAYFIRTLDIDRRIVARLKPRASISKKLADTVIAKEKKHSEDDTLRQAAEDLGVDYDSEEFEKEAKGKKGRGTGRKKKEKEASEMTKGEQQALRAELRGLLSQRINTGVSARYLTSGGIDVDALMAGEGNMEFLGNVDGLGFDEE
The following text describes a protein:
Function:
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
Sequence:
MAKKKTAPKVFEYVEPIGDRVLVRKDEPKRETRGGIALPDAAEIPTITGRIVTISAVVENDEELPLRQYDKILFHPKNAIPVDLEHDNQLFVVPVDDIVAVFRREAPEE
The following text describes a protein:
Function:
Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. ITGA9:ITGB1 may play a crucial role in SVEP1/polydom-mediated myoblast cell adhesion. Integrin ITGA9:ITGB1 represses PRKCA-mediated L-type voltage-gated channel Ca(2+) influx and ROCK-mediated calcium sensitivity in vascular smooth muscle cells via its interaction with SVEP1, thereby inhibiting vasocontraction.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MPAGRRCWARVLSALLWVALACCYNVDVGRPVVFQGPNGSFFGYSVLQHYHDSTRWVLVGAPKADSRYSTSIQSPGAVFKCRVHTNPDRRCTELDMGRGNSRGMLCGKTCKEDRDDEWMGVSLARQPKAGGSVLACAHRWKNIYYETEYILPHGFCNIIPPNLQPSGKKLLPCYEEYKKKYGEEHGSCQAGIAGFFTEELVIMGAPGSYYWTGTVKVLNLTDNTYYKLNDDAVIARRYTYLGYAVTAGHFSQPTTTDVVGGAPQDGGIGKVYIFRTDRRSGSLVKIFQASGKKMGSYFGSSLCAVDLNSDGLSDLLVGAPMFSEIRDEGQVTVYINRGNGVLEEQLVLDGDGAYNAHFGESIAALGDIDDDGFPDVAIGAPKEDNYIGAVYIYHGDANGIVPQYSMKLSGQTINPMLRMFGQSISGGVDMDGNGYPDMTVGAFLSDHVVLLRSRPVITMDISIFLPASINITAPQCHDSLQPVNCLNVTACFRFSGKHVPGEIGLNYNLTADVAKKEKSQQPRVYFVTSGETVGQITEKLELSYMQEKCRHFLAYVKRRVKDVISPIVFEASYSLGEHVIERGKEDKELPSLKPVLRWKKGQKIAQRNQTVFERNCQSDDCAADLKLQGKLLLSSVDDRTAYLALGAVRNISLNISISNIGDDAYDTNVFFNFSGELFFIKMWQKEEQGISCELLESDFLKCSVEFPFMRSKSRYEFSVIFDTSHLSGQEETLTFLVTAQSGNMERMESLHDNTLTLSVPLMHEVDSIVLDVFQTYLHSQLWLYKYFLLMSSHVCLGLLNTSICIFFLQVYNAGPSTLPGAFLDISFPNRLSATGAEIFHVQQMMVGQDKGNCSFHRNRNPCVVPQENENIFHTIFAFFTKSGRKVLDCERPGRSCLIIRCNLSSLAKAESSEISIYTLLNTEILKKDISSVIQFVTRARVQVDPDLRVVEVPNGSPEEKTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNRKETEDSWDWVQKNQ
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MYQPEDDNNSDVTSDDDMTRNRRESSPPHSVHSFSGDRDWDRRGRSRDMEPRDRWSHTRNPRSRMPPRDLSLPVVAKTSFEMDREDDRDSRAYESRSQDAESYQNVVDLAEDRKPHNTIQDNMENYRKLLSLGFLAQDSVPAEKRNTEMLDNLPSAGSQFPDFKHLGTFLVFEELVTFEDVLVDFSPEELSSLSAAQRNLYREVMLENYRNLVSLGHQFSKPDIISRLEEEESYAMETDSRHTVICQGESHDDPLEPHQGNQEKLLTPITMNDPKTLTPERSYGSDEFERSSNLSKQSKDPLGKDPQEGTAPGICTSPQSASQENKHNRCEFCKRTFSTQVALRRHERIHTGKKPYECKQCAEAFYLMPHLNRHQKTHSGRKTSGCNEGRKPSVQCANLCERVRIHSQEDYFECFQCGKAFLQNVHLLQHLKAHEAARVLPPGLSHSKTYLIRYQRKHDYVGERACQCCDCGRVFSRNSYLIQHYRTHTQERPYQCQLCGKCFGRPSYLTQHYQLHSQEKTVECDHC
The following text describes a protein:
Function:
Involved in EGF receptor signaling. Has an early role in photoreceptor development. Interacts with the receptor torpedo in the eye.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein.
Sequence:
MSQQVFSAHPALAVDQLQQAEQEEHNTSSNHHQQRSATQSRRHTKAAPKKFTLSRSCAGGGSGTLSGVHQQVKPSPSNPAISPECRKTLPVRTNYAAVDDDDDIECEDVDEVNFGQQEKERERETRQPTKDCGTDETDHVQQRHKNTMTTSATAASRHHHQDGGGGDQSDLSSVISSPSVSTVSSPLSTPTRLPQALQQQLHCCQKSTGMESRARTSPQQIQHPHRQHHQQQHHHHHHHHHLTAAGCTGGGGGGGGSGGSGSCKAKKLDPRLNPSPYRQLLPIALCLLSFAAVFATLIVYMDTTEIRHQQFRLNMSRDYELNGVAQDDPALIDFLRQIHMGKYLGKASPKVAAAASVGVGPPPNSPRLAAAGSTFGSGNSSGSGADQLAHYVADLVGGKMNGAVIQSLSGPLAHLITAPWLSEQLNWMGVLVEPEPRWYFTLRKQNAQRARMQVVHACVSPNTYPKEITIHNEDVRINSLHDEETSWFNSRVKCFPLYTIMLACERTEYDLLSLGVQGHELEILQTLPFDKVKIDVISIHLLEDHEDVADYVLDITRFLAGKSYKLQRKIGRNYFYQRLNASASRTRKKDILLLKTP