lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Sesquiterpene synthase involved in germacrene A biosynthesis. Germacrene A is a precursor of several sesquiterpene lactones.
Sequence:
MRFRSHSGRFLLSFLRGKKCDKYFRWCFKWSSTQSFVETQDCAKVTSMCLSIQLRCKHFDIVETRRPMELNKKDANILALVQRCKHFDICLRESFPFQTTTDYCYRNEQNRYRPNSCRKPRVVTAETVPRRSANYASSLWSFDQIQSLSSEYVGQDYKAMADTLKDAVKMMIHKGGNQLNTLQMIDDLQRLGISYHFEDEIRNLLEMIYCNYYKTPEEWNGMDLNLKALGFRLLRQHGYQVPQEIFHDFKDKMQNFKPYLADDMMGILNLYEASSYSLEDESILDHARDFTTKYMKENQDKTDKSISSLVTHALELPLHWRVPRVEAKWFIEQYEQRADKNPTLIDLAKLDFDMVQAVHIEDLKHASRWWRNKKWDKKLSFSRDRLVEHFLWSTGFCHLPQHSLGRRTMTKVNSIITALDDVYDVYGTLDELEQFTKVIDRWDINEIQELPDYMKIFFMGFYNTINEIAYNTLTETGFHSLPYLKKAWAGLCKAYLVEARWYNNGHTPTLQEYLDNAYTSISAPAVLMHANFVISVHSSNDILQSMPRLEKTIYYSSLIFRLADDLATSSDELARGDVSKSIQCYMHESGATEEEAREYIKELILETWKKINKERAHANSQFERGFIEYATNISRMALLMYSDGDGHGCPDLTKSHVSSLFFNPLQGI
The following text describes a protein:
Function:
Binds GTP and GDP. Has intrinsic GTPase activity. Does not hydrolyze ATP. May act as a transducer of stress responses.
Sequence:
MGMLDVSLHKITQKSQSLLHRTADRHLRLAVTGLSGAGKTAFITGLVNQLLNSGAVSTVSHSRQNGLPLWQVSREQRLLGVKRAMQPDLEIASFDYQGAMLALTSNPPTWPESTRTISELRLAIKYRPEKGLLAKFADAATLYLDIVDYPGEWLLDLPMLRQSYIEWCTTQQQRIAVLKSSPLYAGFETSLNALNLAAMADESELKRLADQYQQLLHDLVHVQGYYQAQPGRMLLPGEWQGAPLLAFFPLLSVTNAQWSNLKQSDKHSAFHVLEKRYQEYVAKVVKPFYKQHFAGFDRQVVLVDCFSALNRGKSQFEDMGAALNAIMESFQYGQSSYLRRLFAPRIDRLLFAASKVDHVTRDQQSHVLSLLTDMLKHSQHFAGFEGCKVETMAISAIKATRHGMVTTQEGDVEVVQGTGLNGQALTLFPGEVPTRLPEPDFWREQGFNFIGFAPPDNTNVDPSSVHFDHIRLDHLLQYLVGDKLE
The following text describes a protein:
Function:
Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus. Nucleus.
Sequence:
MAAPTRVEISAPSQFPPELKDRAQNFHSALKKVQDILKPFLVSSLDDSTNELLPLDKARLDLTILYAMNSLFWMYLSTTGEDPKQHGVRRELERIKEYMVRARQIADKAKAPKLDQGAAQRFVRNSLWQPKDKEENGAESTPAPHKRPESLTRTPRGPPEKRKRR
The following text describes a protein:
Function:
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Subcellular Localization:
Nucleus.
Sequence:
MVRFKNRYFLCEYIQENQEQEFSERDLFIEIKDQVEYHFGQFGSGNIQFSFQVKYLNSISRLFILRVNREYKNIIWSTLLFMNMFRGVPIKIRTLSCSGTINKCEIRARRLLTKWVHKILKCDMPNRLRNTIIRDYQQTQQILPKLTQ
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MADNLYDSSIIEKQLKEKIENALSIHSYPTAIFFSDKLLNLVTIHSKEYVKILYILCDALYLDRQFQRSSYLIQKYLNAIEEIDKKGEDYQYIDDIHSHHHNQQQNIFYKRIKKEKEDEQYTNTILKLKYLAAKCKIETNEFDQCLQILNKDNDSSENMDDENNNINNNNNKIKKENEINNDNCDDDDDDDDDDDDDDDDEKDSNQLLKFYTNSKSNKSKDISENNSNNENTTKESINKNNTDSSSIDNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNFNKETLIIRSSISCLKGKCYESMDNLKKAKFWYIKALLTDYNCFEAFESLTKNHLLTYQEEISLLEKLKFSSDDSWIKEIYSLSLKKYDSPKFTFNYKYLELYDSLNHQNSNNNTFGANNNNNNNNNNNNNNNNNNNNNSNNDISTEDLISVKTLSSSSSSPSKKQENNNLITINEIRKKLIECNDIQTWISEYYFYRHQFQESYSITKRILKQDKYYSNQICLMVNISSMFELQLTNELYFTCHQLVDSFTSSLNNGSHGGSHGGGGGGSHGGSSGNGGAISWYGVACYYHLIQNSDQTQRFFTKSTTLDSRMGASWLGFGHFFASKGEHDQAMAAYRTSSRLLTGCHLPLLCIGMELIRVHNLNLASQYILQAKDICPYDPMIFNELGIIEYKNSQYNEAIKLFETALEICKIKSKASSSSSSSSNYHNLNLSNISFSGVGSSGIGNNNNNNNNRRTTTTTTTTSNNQKKNSSNNKTMIAYLESWEPTIYNLAHCYRKLRKFELALHYYTMSLSLLPNNPSTYSALGFTHHLQGNFDEAIDYYHQSLSIRDDTFTNVLLHKALSLSILQYD
The following text describes a protein:
Function:
Testis-specific component of the ribosome, which is required for the transition from prophase to metaphase in male meiosis I (By similarity). Compensates for the inactivated X-linked RPL10 paralog during spermatogenesis. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDKVAKKRLIPDGCGVKYVPNRGPLDKWRALHS
The following text describes a protein:
Function:
Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Can hydrolyze ATP in the presence of actin, which is essential for its function as a motor protein. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.
Sequence:
MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTISPKHEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTLLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITVQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILCEHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILGNKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV
The following text describes a protein:
Function:
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
Subcellular Localization:
Cell surface. Endoplasmic reticulum-Golgi intermediate compartment lumen. Endosome lumen. Golgi apparatus lumen. Golgi apparatus, cis-Golgi network. Rough endoplasmic reticulum lumen.
Sequence:
MASPRLCPGSRGLLPAPPLLLLLLLLLLVGPRTAAGHGGKYSREKNEPELPPKRESGGEFRMEKLNQLWEKAQRLQLSPVKLSELHADLKMQERDEFAWKKLKAEGLDEDGEKQAKLTRNLSVILAKYGLDGRKDARAVSSNSLSDATEDDSLEDPRLEKLWHKAKTSGKFSSEELDKLWREFQHHQEKVREYHVLLETLSRTEEIQENVISPFDTSRIKEDVLHSKHAELKDRLRGINQGYDRLRRVSHRGYGTQAEFEEPRVIDLWDLAKSANFTEKELESFREELKHFEAKIEKHNHYQKQLEISHQKLKHVESFGDREHVSRNKEKYAMLEEKTKELGYKVKKHLQDLSGRISRARHNEL
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MISRIARVQRSAAVRSTVRSAMRPATVAPMASFNLRSRFYSDKAETKAEDPEAAAEAAGPAANAADASASGASAAETKTAPTAEEYEALLAKFEKKDKECAQFKEHYQRAITDFRHLQETTKREIKKAHDFALAKFAKDLLDSVDNFDRALGVVPDEIKNDRENNKEIMNFYDGIKMTQDIFEKTLGKHGMKKLEPVGEVFDPNMHEAVFEAPQPDKEAGTVFFVQQTGFTLNDRILRAAKVGVVKGE
The following text describes a protein:
Function:
Required for efficient biogenesis of the 60S ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSTEISAAAPRRAANGKKRANRRKKRRTQAESDSSDSSDSSESSQPSADEQEAKTDDVAVELSDVELSDSENKTVSHSEKLDDESKAKLKSIQLTATDLSSKFALQQNRNIDLQKAGREVDHGLEKLAKLDAQTSEQESGRLKTGYINMLFEHVGEDVNQLRNAPDFTPKSLVVLANALKDGGDMFDIESLRALVDNK
The following text describes a protein:
Function:
Involved in heterochromatin silencing. Required for transcriptional repression at the silence loci of mat3, where it has a direct role as a chromatin remodeling factor.
Subcellular Localization:
Nucleus.
Sequence:
MSTSAIALALSSSKAIEQLDHVQTETPNLKQEMSESPSNSGVASKRKLQSTEWLDPELYGLRRSGRTRSNPGRYVDTDDQEDVFPSKHRKGTRNGSSFSRHRTIRDLDDEAESVTSEESESDDSSYGGTPKKRSRQKKSNTYVQDEIRFSSRNSKGVNYNEDAYFESFEEEEEEEMYEYATEVSEEPEDTRAIDVVLDHRLIEGHDGSTPSEDYEFLIKWVNFSHLHCTWEPYNNISMIRGSKKVDNHIKQVILLDREIREDPTTTREDIEAMDIEKERKRENYEEYKQVDRIVAKHLNSDGSVEYLVKWKQLLYDFCTWEASSIIEPIAATEIQAFQEREESALSPSRGTNYGNSRPKYRKLEQQPSYITGGELRDFQLTGVNWMAYLWHKNENGILADEMGLGKTVQTVAFLSYLAHSLRQHGPFLVVVPLSTVPAWQETLALWASDMNCISYLGNTTSRQVIRDYEFYVDGTQKIKFNLLLTTYEYVLKDRSVLSNIKWQYMAIDEAHRLKNSESSLYEALSQFKNSNRLLITGTPLQNNIRELAALVDFLMPGKFEIREEINLEAPDEEQEAYIRSLQEHLQPYILRRLKKDVEKSLPSKSERILRVELSDLQMYWYKNILTRNYRVLTQSISSGSQISLLNIVVELKKASNHPYLFDGVEESWMQKINSQGRRDEVLKGLIMNSGKMVLLDKLLSRLRRDGHRVLIFSQMVRMLDILGDYLSLRGYPHQRLDGTVPAAVRRTSIDHFNAPNSPDFVFLLSTRAGGLGINLMTADTVIIFDSDWNPQADLQAMARAHRIGQKNHVMVYRLLSKDTIEEDVLERARRKMILEYAIISLGVTDKQKNSKNDKFSAEELSAILKFGASNMFKAENNQKKLEDMNLDEILEHAEDHDTSNDVGGASMGGEEFLKQFEVTDYKADVSWDDIIPLTEREKFEEEDRLREEEEALKQEIELSSRRGNRPYPSSAVESPSYSGTSERKSKKQMLKDEVLLEKEIRLLYRAMIRYGSLEHRYNDIVKYADLTTQDAHVIKKIAADLVTASRKAVSAAEKDLSNDQSNNKSSRKALLITFKGVKNINAETLVQRLNDLDILYDAMPTSGYSNFQIPMHVRSVHGWSCQWGPREDSMLLSGICKHGFGAWLEIRDDPELKMKDKIFLEDTKQTDNSVPKDKENKEKKVPSAVHLVRRGEYLLSALREHHQNFGIKSSPAISTNGKTQPKKQTANRRQSGKPNVKSAQKIESATRTPSPAISESRKKPSSKDTKIETPSREQSRSQTASPVKSEKDDGNVSLNAEQKARCKELMYPVRKHMKRLRKDSSGLGRAELVKLLTECLTTIGKHIEKTVNDTPSEEKATVRKNLWMFACYFWPKEEVKYTSLISMYEKMK
The following text describes a protein:
Function:
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Requires the other members of the gamma-secretase complex to have a protease activity; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Domain:
The PAL motif is required for normal active site conformation.
Sequence:
KMCHSMTAQYRHIMRQVITLICALSICMASVACLVRILKPSKNDGMSQPYVRYPVEYDAEPVLLMNSFANAFSFLSMIMIVNCTLVLLYKGGYTNVIKAWLMTGSGVLLFVVTYYYMGRCVYYFNFPMDHLSCSFIVWNIGMTGMGTLYYKGPFVMHQGFVIYVSILMAVVLEESFPEWTAWILMILVSLWDMFAVLCVIGPLRMLIETAHERNEPLFPALLFSTSSAWCYDLSAQTPTNAEKLPRRLLNFRGSTNTEDSFVVSRMKAIQEIRRQEDVLCSHHHHHTHQPRHHRQRRQDAAAPEDTGMKMGLGDFIFYSILVGKASRHGTVSAVVICYIYVVIGIILTLALLVIAQKPVPALPLSISLGMFAYFSTISFVEPFMEETGVLSL
The following text describes a protein:
Function:
Involved in the caffeine degradation, which is the essential first step for assimilating the carbon and nitrogen in caffeine. Catalyzes the N1-demethylation of caffeine to produce theobromine and formaldehyde. Also catalyzes the N1-demethylation of theophylline, paraxanthine, and 1-methylxanthine to 3-methylxanthine, 7-methylxanthine, and xanthine, respectively. NADH is the preferred substrate.
Sequence:
MEQAIINDEREYLRHFWHPVCTVTELEKAHPSSLGPLAVKLLNEQLVVAKLGDEYVAMRDRCAHRSAKLSLGTVSGNRLQCPYHGWQYDTHGACQLVPACPNSPIPNKAKVDRFDCEERYGLIWIRLDSSFDCTEIPYFSAANDPRLRIVIQEPYWWDATAERRWENFTDFSHFAFIHPGTLFDPNNAEPPIVPMDRFNGQFRFVYDTPEDMAVPNQAPIGSFSYTCSMPFAINLEVSKYSSSSLHVLFNVSCPVDSHTTKNFLIFAREQSDDSDYLHIAFNDLVFAEDKPVIESQWPKDAPADEVSVVADKVSIQYRKWLRELKEAHKEGSQAFRSALLDPVIESDRSYI
The following text describes a protein:
Function:
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
Subcellular Localization:
Nucleus.
Sequence:
MADDISTLAGKMRHLTLEKDLIVNVNMKKFPHGPITRRGKERSIRIFSESREVGTAFRQGLVYDLDDKKNLPLLNDEICEYISHRSKSKLIGYVGSDLSVGSETFHPVTSEELHCLHGLLKFIAKWEADNEVNYASRSKFTIVSPRHHILDILMIPFGNERCRLVFTAHRGLFVITLAPSQRPTGINSPSSATRKICYTGFELERLLTATSGTERGSFYSFIEAKLEPDITILLQCEMDAYNPKRQKYTEIKSSVDFNVRNVRHLSKLLKIWAQTALLPSTDILVGFRDPSTHVLKTVVPYSVDQIAEKLYIRDRTRSHPSYFNFNPEVAKDWTHYAIREICERLSSLVDATSSSPQSFLVEIDKNLQMKIRPTVVDYSELLGQWA
The following text describes a protein:
Function:
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
Subcellular Localization:
Secreted. Bacterial flagellum.
Sequence:
MSLSIHTNASAKTAINSLSNAGLSNAKSSQRLSTGFRINSPADNAAGLQITNRMEKFLNSAGQAKQNIQESIAMLQIADGGLAESVKTLNAMKKLATQAANDTNSAADREAIQKEFSELGKELQNALNNTEYNSEKLFADGGKMRKELNFQSGTDAESSLKLDLNSVIAELTESVTKKATPVKADVAGSTLEKEADVLDKATKAAKKAKEAAEGVQKTLETDFAVAGNKASAKITIPEYKDALGKTVPEVVINSGTAITPANSTQMKDAVAALKATHDAAVKAEATFQAKNSTGGGVMNMQLADKDLAMKADKKLSDVIDAYGAFRATLGANQNRLQSSSNNLDNMISNTAQALGSIKDTDFADEMKNHAQSEMLMQSSVMMLKKANAATQLISTLLQG
The following text describes a protein:
Function:
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSAAPKLKRKKKVKFCPNPLFVQWLTEWRDAAAEKGIKTQYAYGKALVALKKYPLPFQSGKAAKILDNFGDKICSMLDKKLEEHLANEAESSSTAVDVDDDSDEIAVCSPVGMQFNETMNGSTRKRKQASPRSATKRVREYIPLDRSGPYSLILTLYRNHTRPGSKGFMHKTELQDAAQPLCDKSMKMPDPGGHYTAWSSMSTLVTKGYVYKEGSPARYVITESGCELAHKLEATTGQHPITDHLPRMASLDNTIPVAQEDQRSEVTSRRSALEIPNYWYIDDRGREVTLKDRAAVTVNDDGVGFLIKCSEASLRSCSLRYKIDRGRTAPPGSCYAYLHNDDASEVCPASKSSPPANGEHDGAVEISKKTSHSHSNSRSTNSSYVPSTNSSYVPSTHPTSSSFTAVPKSRHGMDSDDMTTSAPGSERTGSSTTPTPVFSLRPGQFDVILCVDNCETTGIGGKEKGRKHVLLKELQKNGVNLDVRKLQVGDFLWVAREKGSAVPGLLQMPRRREAVLDYVVERKRMDDLCSSIQDGRFKEQKFRLKQCGLGHPVYLVEDFGSTDHMSLPAATMLQSVVNTQVIDNFFVKNTRDSKESAAYLTIMTRYLNSLYSDKTIKAYSREDMDKLTGSTDLNSPQQRCLSFREFNESSVKNKEMTVTETFAKQLLQFGGMSAEKALALTQIYQTPSDLIRAYETCSLPSDQEKMLAKVKYGQSQRNMGPALSKVVYQLYRSSNALT
The following text describes a protein:
Function:
Acts as an inhibitor of GDB1, enhancing the ability of cells to store glucose as glycogen.
Miscellaneous:
MISCELLANEOUS: Present with 639 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MTDPHLNTPQVSTSPTFERSQDFLNIDEPPCAQETPSVSTFNLPGPSAPAQSVDKPVPMIRRRSTNYMDALNSREQARERESSIGEHAPGAERRSSGPMDFQNTIHNMQYRTTNDSDLSHAGVDMGDSISHTPICSRAGNRPIFKNSYLDNNSNGNSARVPHGSPPQLGTRRKSSFKYEDFKKDIYNQLHMFGEK
The following text describes a protein:
Function:
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MIPSCLSTQHMAPREDLVQSAVAFLNDPQAATAPLAKRIEFLESKDMTPEEIEEALKRAGSGSAQSHPGSVVSHGGAAPTVPASYAFQSAPPLPERDWKDVFIMATVTVGVGFGLYTVAKRYLMPLILPPTPPSLEADKEALEAEFARVQGLLDQVQQDTEEVKNSQVEVAKRVTDALKGVEETIDQLKSQTKKRDDEMKLVTAEVERIRDRLPKNIDKLKDSQEQGLADIQSELKSLKQLLSTRTAASSGPKLPPIPPPSSYLTRKASPAVPAAAPAPVTPGSPVHNVSSSSTVPADRDDFIPTPAGAVPMIPQPASMSSSSTSTVPNSAISSAPSPIQEPEPFVPEPGNSAVKKPAPKASIPAWQLAALEKEKEKEKE
The following text describes a protein:
Function:
Required for nuclear migration during mitosis. It is required for the normal initiation of translation.
Sequence:
MVADTKLYDCLEVRPEASEAELKKAYRKLALKYHPDKNPNGEKKFKEISLAYEVLSDPQRRKLYDQYGITEGNAAPPPPGAEGGPGAGFGGFPGAGPGGARTFHFNMGGPGGAQFFSASDPNDIFERVFGHAFAGGGGMGGGMGGMGGMDDDMDMDGGFGTRTRGGGMPGGFANMFGGGGAGPHARRSHPSFGGSRPSQPPAQNEVITRPLNVSLEDLFTGCTKKMKISRHIIDASGQSVKADRILEIKVKPGWKAGTKIKFAGEGDEKPDGTVQDIQFVLAEKPHPVFTRSGDDLRMQVELSLKEALLGFSKQISTIDGKKLKVSSSLPTQPGYEITYPGFGMPLPKNPSQRGNMIIECKVKFPTELTPAQKTAAEAF
The following text describes a protein:
Function:
Efflux pump; part of the gene cluster that mediates the biosynthesis of dothistromin (DOTH), a polyketide toxin very similar in structure to the aflatoxin precursor, versicolorin B. One function of dotC may be to transport early-stage dothistromin biosynthetic intermediates from the cytoplasm into vacuoles, thereby affecting the rate of dothistromin production.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MASAARGSRGTPAVDSSTLTQTSAAASDNGSSSDNTVQNNINNPQAKEEQEKEQELERANEDADPTAPPTDPPTTVTGPSAAPEEGRTSLETTAIILALASALFLAALDVTIVTVAIPTISEEFGSTTGYTWIGSAYLLANAATAPMWGKISDIWGRKPILLMTVGVFWIGSLICALSKNMGMLLAARAIQGVGGGGIIILVNICISDLFSMRKRGIYFGVMGMVWALASAIGPILGGTFTSKVTWRWCFYINLPISGVGMAILAFVLKLHNPRTPIRQGLMAVDWLGSVTIVGGTLMVLLGLEFGGVSYPWKSATVICLIVFGIVVIGIFGLIEWKVAKYPVIPMRLFKRRASVASLLVCACQGFVFISGSYYLPLYFQAVLGATPLLSGVYVLAFAMSLSIVSAATGVYIKKTGKYLPPIIFGMTVMTLGFGLFIDLEPRPNWAKIILFQIVAGVGVGPNFQAPLIALQTTVPGRDVAAATGTFGFIRQLSTSVSVVIGGVVFQNRMEKQHERLVQELGPKNASLLTGGSAASNVGRLASLPPDQRQIAREAYFNALRTMYIVYVAFAALGLFVSLFVGSRTLSKEHEEHKTGLDNMKKAKEDAAGEGRRRAPVDEEKAGSR
The following text describes a protein:
Function:
Involved in the regulation of phagocytosis. May repress ChLim and activate rab21.
Sequence:
MSGQNILKCKKCQLEITNKIITNHNSDTFHEQCFVCKLCSTPISDPYFTDKETGDFYCAKCEVIRNDQSKPLRESLGFCSLCYKYFRQNEDILTIDLERYHIGCLKCTICKKGINNEKYYREKMTSKLSNYCCEDCFEKVDKCNGCNSMTLGQTLLAMGKNYHANCFKCFKCSEIIKPNSPYSINKQTNTPSCQKCN
The following text describes a protein:
Function:
Involved in pre-25S rRNA processing.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAKHSAHKGKAPVTDKNNKRKRDAQDSSQGDAPVALFAAVKDTELDDIFAKSNAFSAPAPVASTSKAHLQTTSAPAAKKGKKSPSPEMEEDVRVDDQDESESSEEDEDGEDNEAELSEIDEELPDDDDEDVSDAESDSEAAKAKETKKTKKSKLGKYVPAEESVQDKNRRTAFIGNLPIDAAKSKSTLKQLRAHIMSFVPSAKIESLRFRSVAFATPTAALPTEDPEKDANQRAKREKERAAAWKAKQNADGEDAELDKAKVFIDAKGKRKVAFIKKDFHSEIDSCNAYVVFAYPHPDRAANVAPILDPFEAAAKFIASANSSTFSGRTIRVDSVRLPSSVGLAGASTSLSKRDAWLPSNTDPKKSLFVGGLDYAAKEEDVRVFFEELVKAERGANKEGSGKWVTGVRIVRDKETQLGKGFGYVHFADRESVEEILAMDAKQIKFAKRTLRVQPCKTIPTANTLQNTIKKIAAGSGGASKDKTKKAYVRPGVIPKGDPALGDKLKNLSKEERKTIKSSDADRQARRLAKKKAKMSLEKDKAKGAVKLTLTKSEREKTSASKKPKAKKGKKRAPSAVAKMKGSRE
The following text describes a protein:
Function:
Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
Subcellular Localization:
Nucleus.
Sequence:
MSVDVAAIRAAFAACNLDLEEDATATCVSICTEFGLSSDDMAAQWDAYSMNQQLSGAADADGLVAFRTHLKQQQQKSKAKDPTPTSASQKKRQTKTPVVKREAESQDKLESLYNVKSPEGKHARPFASPTGSNKVQRTDGMFSPSSMQSPPGNSYEKRTDAGKTVSEFNAHLKKQIEGLGANTGRPVKVAAPFPSRNLASNASYMYTPLFQRAIALDEQLVEYEELVKKKFNLEELKPVGDPSPAQVTVVGRIVCEAAEGKLNPSVVQIEGTRKTCGGQRVLLDLSGVPNFQIFPGKIVALEGIFPDTRSPMAVKRFLEIVIDQQPDVLVLVGPFIDSIHSMFQDGLVKYDGMMLSFEEIFLFKVMTLLNNVLEKNEQIQIVIVPSLRDANHEYVYPQPPLNKKKACEAFESPEYAKRVHFMSNPSTFSINGVVFGTSALDVVVQLSSNELYRAQTRDQNRLLRLCEQVIDQRSYYPMFPPPPNSEAPIDLRYMKQFQFEQTPDILLLPSILNRFCGRVKDSICINPGQLCKGESGGTFAHITILPLSNDKIESVADDTSAHFVPDRTIVEIKRI
The following text describes a protein:
Function:
2-oxoglutarate-dependent dioxygenase essential for auxin catabolism and maintenance of auxin homeostasis in reproductive organs. Catalyzes the irreversible oxidation of indole-3-acetic acid (IAA) to the biologically inactive 2-oxoindole-3-acetic acid (OxIAA).
Sequence:
MESEREIMMIPCFDFGKALEEGSEEWKEMSKKVREACESHGCFLLVCDEMIPKGVREEFFSNMEALFDLPEERKMKHISPKPYSSYSGKSPVIPLSETFGIDDVPLSASAEAFTNLMWPQGNPPFCETLKIMSSKMLKLSSLILKMIVEDYGIQQHYISDVEKMKSSSNSRLIKYKIPENNNDSNTGLVSHTDKNALTIICQNEVQGLQVLSKTDNWIELEMALWSLLAWSNGRLHAATHRVMMSGDKERYSFGLFTMPKEEMDIEVPIELVDEKIHPLRYHPFKYGEYISYFVSNLKENALEVFAGL
The following text describes a protein:
Function:
Acts as a receptor for colicin S4.
Subcellular Localization:
Cell outer membrane.
Sequence:
MKKLTVAALAVTTLLSGSAFAHEAGEFFMRAGSATVRPTEGAGGTLGSLGGFSVTNNTQLGLTFTYMATDNIGVELLAATPFRHKIGTRATGDIATVHHLPPTLMAQWYFGDASSKFRPYVGAGINYTTFFDNGFNDHGKEAGLSDLSLKDSWGAAGQVGVDYLINRDWLVNMSVWYMDIDTTANYKLGGAQQHDSVRLDPWVFMFSAGYRF
The following text describes a protein:
Function:
Alanine aminotransferase involved in both alanine biosynthesis and utilization.
Subcellular Localization:
Cytoplasm. Mitochondrion.
Sequence:
MSDLDGFCQNAFSDLNSLNQQVFKANYAVRGALAILADEIQDDLLENPSSYPFSEIVYANIGNPQQMGQSPITFVRQVLSLCQYPTLLDHAEEKWFQNLFPTDVVQRSKMLLKESGSLGAYSASQGIPLVRRHVADFIRARDGFDCEPSDIYLTSGASHAARLIMTLIIARPTDGVMVPAPQYPLYGAQIDLMSGSMVSYSLSEENNWDIDFDQFKKSFDEASKKGINVRLCVVINPGNPTGACISENSMEKVLRFAKAKGIVLLADEVYQNNIYQNKFHSFRRKLGELREKEPDNHWDQVSLISVNSVSKGQFGECGQRGGYLDVVNIPEPAKDQILKLATIDICPPVAGQLLVDMLVNPPKPGDPSYDLFIKEVDEIHEALRLQCRQLYEGTKRMKRVSCLEPHGAMYLHPSVSLPEKLITTAKAQKIQPDEFYAIELLKRSGICVVPGSGFGQPEGDYHIRITFLAKGTEYIERFVKAHNEIMDLYE
The following text describes a protein:
Function:
Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MNPDDEFDAVVLAFLGGKVPVSSSSDLDRVSFMGIEDYKHQHKKWIFGECNSRVSDLLLKKGCEKQVNALDCEVTVHPTRGLFCHIEVLGSQSRFEPSQIVAVQDRAGELKAIGIVTGVINDRTILRAHHGTKPVKGKYDVFLLDTTATLRRCFLSVSKAENISPRLRDQLVRPLNTIRPEAVHFGAWLAGLRLNHEQGRVVAASVHLREGFLLAQGIVSAALCATRYAKILVCAPYNNAVDQIALSLSSRLLDSDGQAYVPRRGAIVRVGPMEKIDRHCHGLTLEGIIISEQRAYSSYYIAEENVLSNASVVCTTLSCSDSFHLEKWNCKFDLVLIDDAAGIAEAEILIALAKARDRCILLSDSIRKCSAYRRSLFHRLEQAGLVPYLLERPPNVTSEGPSSEVARHRQEDSKYNRNYEKHRHEEARASQIYDQEARRNRHDGEKECHRGGDRRDGHDAEKERHHGDRQPGVRSVDGVKELQKAKVSRAEVKIENAANAASEKRVATQAAATRVKMEPDSGGEGLENGPSFPAASAACQKDKELREMGSQRCETNNESTVMRQPKSERCGRTASEAPCKESTGKVAENKLQKRRGEHEATEMNQQRGNENCEKVLTGASCQTNKESTAVPQRQNELCEKAPMEGVCQIKKEKVAGDNQANNESMGDKQQRSREHCEQAHTEALFQKVSDEQQQLEAGSTGAVCRINNEKAPLNLVELKQEQAQDNQTLAAEKLQAEKYLRKKSESQETEQELVQDGGAQAQQEQQEEREWPVKVKLAGKKKQIQGQAEQKSLEYDGGTQTDQQQKEQCSEKETLSEKEINPFQPSLEVVKNRKETRKEVEQEEQQQIEDQKENQLQAEPVKKRKKKRKELKQDGGAQVEQGQEQPQPEEENVEHVKKRKKKRKELEPDGVEKETLVAEGKEKNQLVFAEEKNSELSENPKKKKKKKKRQALEQIQDGQQQVHEEERPYHEKQGLEKEKQEERMELQSKRKKKKRTFSEQEHWDRNGGAQAVIEWDGGLMPEKHYVELDEEILDLAIAQLPRDGSAIPHQILEAVVAFVLEMDDECGIVVAQRVAGDQIGEKTAGKAMLFQESRHLGAGENGVSGEGQSRQRCQEEEQWRKHEHHLSPLRARLEVPKVPEVPVIPEVPEVPEVPVIPEVPEVPEVPVPEVPSEIPKVPELPKVPEVPVPRVREYPVLSEIPPKKPVPEVPKVPEYLVVPEVPLKKPVPKVPKFPVIPGLLPSGMIPGPGVRDRVFHSQAISRWCYFCMGIAMLRPGFY