lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the Bil (bacterial ISG15-like) antiviral defense system, composed of BilA, BilB, BilC and BilD. The Bil system specifically conjugates a ubiquitin-like moiety (bilA) to the bacteriophage central tail fiber (CTF, or tip attachment protein J) via reactions involving E1 (bilD) and E2 (bilB). Modifies CTF of phage SECphi27 and SECphi4, which probably interferes with assembly of the phage tail. Also modifies T5 baseplate hub protein pb3 (gene D16), but not gp27 of phage T6 (Bil defends against T6). BilD (E1) catalyzes the first step in conjugation. Activates ubiquitin-like BilA by first adenylating its C-terminal glycine residue with ATP, and then conjugates it to the side chain of a cysteine residue in E1 (this protein), yielding a ubiquitin-E1 thioester and free AMP (Probable). Bil-encoding bacteria produce mostly defective phage SECphi27, many of which have phage assembly defects, including no tails. SECphi27 phage progeny produced in E.coli with the Bil system inject less DNA into naive host cells, maybe because the phage are less able to adsorb and inject their DNA into host cells; Expression of the Bil system in E.coli (strain MG1655) confers about 100-fold resistance to phage SECphi27, SECphi18, SECphi6, SECphi4 and T5, but not to SECphi17. When cells expressing the Bil system are infected by phage SECphi27 at low multiplicity of infection (0.03 MOI) the culture survives, at 3.0 MOI the culture collapses at the same time as cells without the Bil system.
Sequence:
MNLTLDHTTLHRAAKYFMDSGKAASHEAAMNLLQQFGLTIYVGEEIRSSAAHQIALLTIVNVTRRTLLGGVEVIGLPDCDSLTALAPNTGLKEAVMALGGTPVAVARPEWPTALIGSVEDYSNKDTAWRVTWEGWRAGAAPLMIGDRLSEDNSMALAPALAAAVCAGEVFSHYAGDHPMAGRRTAGLSLWQPGADWLDVDESEPELAFLPSNLWIIGLGNLGQAFAWLLALMPYETPQELQLVLQDYDRIAPSNDSTSLLSYKHDTNKMKARVVADWLDKRGFTTFIEERRFGPWTKRHADEPGVALCGVDNALARSALDQAGFPLIVEAGLGGGPQAFRSLGIHTFPSSRTAAEIWAKQVALADTSTEDMPAYQALKKSGIDACGLTQLASRTVGVPFVGLIAACLAMSELLRRLHGGKAFEFIAGSTATLQDIEFGTLHAPPYAHGYTRAMPMGWPTAP
The following text describes a protein:
Function:
Spermidine sinapoyl-CoA acyltransferase that mediates the accumulation of disinapoyl spermidine conjugates in seeds. Catalyzes the two conjugating steps required for the biosynthesis of N1,N8-disipanoyl-spermidine. Can also use putrescine as an acyl acceptor to convert it into monosinapoyl-putrescine.
Sequence:
MPIHIGSSIPLMVEKMLTEMVKPSKHIPQQTLNLSTLDNDPYNEVIYKACYVFKAKNVADDDNRPEALLREALSDLLGYYYPLSGSLKRQESDRKLQLSCGGDGGGVPFTVATANVELSSLKNLENIDSDTALNFLPVLHVDIDGYRPFALQVTKFECGGFILGMAMSHAMCDGYGEGHIMCALTDLAGGKKKPMVTPIWERERLVGKPEDDQPPFVPGDDTAASPYLPTDDWVTEKITIRADSIRRLKEATLKEYDFSNETITTFEVIGAYLWKSRVKALNLDRDGVTVLGLSVGIRNVVDPPLPDGYYGNAYIDMYVPLTAREVEEFTISDIVKLIKEAKRNAHDKDYLQEELANTEKIIKMNLTIKGKKDGLFCLTDWRNIGIFGSMDFGWDEPVNIVPVVPSETARTVNMFMRPSRLESDMVGGVQIVVTLPRIAMVKFKEEMEALE
The following text describes a protein:
Function:
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MPAGERLPGAPAREERIVVHVDMDCFYASCERRREPALRGAPVVVGMGYEPDQTVGAVATASYEAREYGVESAQAISAALERLPRKADAPDASAAGYYRPVDMAYYESVSESVSEILHGLGDPVREVSIDEAYLDVTDRTAWDVAAGFGRHIKQRIARSVGVPASVGIAPDMSTAKLASDHEKPDGLVVVPPESVQSFLAPLDVADLHGVGPVHARALRERGIETVGELADADPYVLEAAFGERGREFHRRARGADSRPVEPRGKPKSLSRESSFDGATESFDRVREQAAALSGAVADRASRTNASYRTIGVKVVTPPYDVQTRAESLPGPVDDPALLEAVSQSLLDEFEGAAVRKVGVRVSNLVFSEREQATLAGFSGDETGDGGGHEGGACGGAGRGSCGGQTTLDEFT
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MMAPELDKQYSNIQLGEEVEICDIKLALKALRKKILSLDFHNSLHVHDPQNSFEYLEVLYKLRQLSEKLGNLDPGGEAKEHKELTVYADDLFEMAMARLEEEFVYLLTYYKQPLEQELLSFRTTEDGSTDEFSSSSFSEEQSEGKSTQTGSSGGSEYLVADLIQPGALSAVKSIANFMFLSNYNNECCQAYINARQGALDEFIGSLHIDKHSIEELMSTKWNKLSASIKRWNRAMKAFVRVYLASERRLSSLVFGDLSETTVDLCFYEISFSSVMQLLSFYESVAIGPLKPEKLFRILDMYEVLDDLLPEAEFLFQAGGNDMVLAEYHEVLLQLGESARKTFAEFKYAIQSYTSSSAVPTGAVHPLTKYVMNYIKAVTVYSKTLDSLLKDADQQPIPNSCTHFTATALHLQSVAAVLEANLEAGSRLYRDCRLRNIFMMNNICYMVQKVKNSDLKSFLGDDWIRLHNRMFQHQATNYERASWSQVLSYLSDDGLCAAGGAASRKIIREKFKNFNLSFEDVYRVQTAWSVPDDQLREDVRISISLKVIQAYRTFVGRYSAFLDGTKQRDRYIKYRPEDLEELLLDLFEGTQKSLQHSGRA
The following text describes a protein:
Function:
N-methyltransferase; part of the gene cluster that mediates the biosynthesis of gliotoxin, a member of the epipolythiodioxopiperazine (ETP) class of toxins characterized by a disulfide bridged cyclic dipeptide. The first step in gliotoxin biosynthesis is the condensation of serine and phenylalanine to form the cyclo-L-phenylalanyl-L-serine diketopiperazine (DKP) by the NRPS gliP. GliP is also able to produce the DKP cyclo-L-tryptophanyl-L-serine, suggesting that the substrate specificity of the first adenylation (A) domain in gliP is sufficiently relaxed to accommodate both L-Phe and L-Trp. The cytochrome P450 monooxygenase gliC has been shown to catalyze the subsequent hydroxylation of the alpha-carbon of L-Phe in cyclo-L-phenylalanyl-L-serine whereas the second cytochrome P450 enzyme, gliF, is presumably involved in the modification of the DKP side chain. The glutathione S-transferase (GST) gliG then forms a bis-glutathionylated biosynthetic intermediate which is responsible for the sulfurization of gliotoxin. This bis-glutathionylated intermediate is subsequently processed by the gamma-glutamyl cyclotransferase gliK to remove both gamma-glutamyl moieties. Subsequent processing via gliI yields a biosynthetic intermediate, which is N-methylated via the N-methyltransferase gliN, before the gliotoxin oxidoreductase gliT-mediated disulfide bridge closure. GliN-mediated amide methylation confers stability to ETP, damping the spontaneous formation of tri- and tetrasulfides. Intracellular dithiol gliotoxin oxidized by gliT is subsequently effluxed by gliA. Gliotoxin contributes to pathogenesis during invasive aspergillosis. In macrophages and neutrophils, gliotoxin showed inhibition of various different cell functions including cytokine production, antigen presentation, phagocytosis, and production of reactive oxygen species.
Sequence:
MTVLPDSENGYLLNYEDQEKRRMNMQHDLIKTYMGKLILAPLPFDQPNLRVLDSGTFNGLWLEDASTLLQSPTLVGTDVSPTAFPAKRPPNTEFHVQSISDPWPTEWRDSFDLVHQKLVIACVPPDEGRQALYRLIDLAKPGTGWVQFTEGSLEHLTPEQRKQYPVLARFQSLVAEMLPHFRWNPRPGKLVRQWLEEYGLQEVQEKVMEIPIGAGNPDPKLGEMAKQNMLEVVSNFRTAATRLPDGTGIRAEDFDPILRDIKVEFETVGGILRFNTVWGRRP
The following text describes a protein:
Function:
Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition.
Miscellaneous:
MISCELLANEOUS: TMEM138 and TMEM216 genes are adjacent and are aligned in a head-to-tail configuration. They share some cis regulatory region and display coordinated expression. Genes were joined by chromosomal rearrangement at the amphiboan to reptile evolutionary transition around 340 million years ago.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Sequence:
MLPRGLKMAPRGKRLSSTPLEILFFLNGWYNATYFLLELFIFLYKGVLLPYPTANLVLDVVMLLLYLGIEVIRLFFGTKGNLCQRKMPLSISVALTFPSAMMASYYLLLQTYVLRLEAIMNGILLFFCGSELLLEVLTLAAFSRI
The following text describes a protein:
Function:
Involved in the regulation of shoot development and salicylic acid (SA) homeostasis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGSILESSTIENEAIETQYLQKGVRHLCERGLTRVPSKYILPINERPNLGDTRVNAGNLNLKLPVIDFTQFQGSDRCQAIHSLEKACREFGFFQLVNHGIKDDVILRMVNVSRRFFELPFDERAKYMSKDMASPARYGTSYNQSNDKVFCWRDFLKLSCQPLEDTVPCWPSSPEDLREAVVSYSKSTNFLYLMLMEAILESLGLEETTESAERKSRSIEEFEDGSQLIVANCYPACPEPDLTLGMPPHSDYGLLTLLLQDEVEGLQIQHEGRWVTVEPLPNSFVVNVGDHLEIFSNGRYKSVLHRVLVNSCKSRISVASLHSLPFNSMVRPSPKLIDQANPLRYKDTDFATFLRFVSSHDMNAKTFLESRKLTS
The following text describes a protein:
Function:
Adenine glycosylase active on G:A and C:A mispairs, as well as processing 7,8-dihydro-8-oxoguanine:A (8-oxoG) mismatches. Minor activity against 8-oxoG:G and 8-oxo:T mismatches is also seen. Bind dsDNA oligonucleotides containing the above mismatches.
Sequence:
MPHILPEPSVTGPRHISDTNLLAWYQRSHRDLPWREPGVSPWQILVSEFMLQQTPAARVLAIWPDWVRRWPTPSATATASTADVLRAWGKLGYPRRAKRLHECATVIARDHNDVVPDDIEILVTLPGVGSYTARAVACFAYRQRVPVVDTNVRRVVARAVHGRADAGAPSVPRDHADVLALLPHRETAPEFSVALMELGATVCTARTPRCGLCPLDWCAWRHAGYPPSDGPPRRGQAYTGTDRQVRGRLLDVLRAAEFPVTRAELDVAWLTDTAQRDRALESLLADALVTRTVDGRFALPGEGF
The following text describes a protein:
Function:
May function in the second step of pre-mRNA splicing. Regulatory protein involved in replication and mitotic spindle formation and/or maintenance. Required for initiation and completion of S-phase and for initiation and completion of DNA replication. Might be required for the maintenance of microtubules. Essential only at elevated temperatures.
Miscellaneous:
MISCELLANEOUS: Present with 1630 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MGLVDGYDTSSDSDLNFDEGKSVHEKKNGNLHEDTSYEPSSNNIHKRKSHFTKSELKRRRKTRKGDGPWGSWSSSDDETSQASETQKEDQDIFVHALAEDNLDSEQIEVEEVSHFYGKSEKDYQGRGYLYPPNDVDVDLREERISFRCYLPKKVIRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIWDTETGKVKTRLHLNSTPADVESRPTNPHEFIVGLSNSKILHYDDRVSENQGLVQTYDHHLSSILALKYFPDGSKFISSSEDKTVRIWENQINVPIKQISDTAQHSMPFLNVHPSQNYFCAQSMDNRIYSFSLKPKYKRHPKKIFKGHSSAGYGISLAFSGDGRYICSGDSKSRLFTWDWNTSRLLNNIKIPGNKPITQVDWHPQETSKVICSGAAGKIYVCD
The following text describes a protein:
Function:
Acts as a component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. Involved in pollen tube growth by modulating Golgi morphology and vesicle trafficking homeostasis leading to the deposition of cell wall components and proteins at the pollen tube tip. Required for sporophytic development.
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MATKAASSSSLPKSGAISKGYNFASTWEQSAPLTEQQQAAIVSLSHAVAERPFPANLVHEHVHRPENGLSVSVEDTHLGDSGAIEAVLVNTNQFYKWFTDLESAMKSETEEKYRHYVSTLTERIQTCDNILHQVDETLDLFNELQLQHQGVTTKTKTLHDACDRLLMEKQKLMEFAEALRSKLNYFDELENVSSNFYSPNMNVSNSNFLPLLKRLDECISYIEDNPQYAESSVYLLKFRQLQSRALGMIRTYILAVLKTAASQVQAAFRGTGGNKTSVSEGVEASVIYVRFKAAANELKPVLEEIESRSARKEYVQILAECHRLYCEQRLSLVKGIVHQRVSDFAKKEALPSLTRSGCAYLMQVCHMEHQLFTHFFPASSEEVSSLAPLVDPLSTYLYDILRPKLIHEANIDLLCELVHILKVEVLGDQSARQSEPLAGLRPTLQRILADVNERLTFRARTYIRDEIANYTPSDEDLDYPAKLEGSPNTTSETDLRDDENADVFKTWYPPLEKTLSCLSKLYRCLEQAVFTGLAQEAVEVCSLSIQKASKLIIKRSTTMDGQLFLIKHLLILREQIAPFDIEFSVTHKELDFSHLLEHLRRILRGQASLFDWSRSTSLARTLSPRVLESQIDAKKELEKCLKTTCEEFIMSVTKLVVDPMLSFVTKVTAIKVALSSGTQNHKVDSVMAKPLKEQAFATPDKVVELVQKVYAAIQQELLPILAKMKLYLQNPSTRTILFKPIKTNIVEAHTQVESLLKAEYSAEEQANINMISIQDLQTQLDNFL
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MASSSRNRRHWDGSNDNGDDYDSPMQLLDSEDDDDGDIQLQQILFYSAMSKPKSNPNDVKKKGIDYSCSFVETDGVSLRNSEYEKGGPSYVVCTMCNEPTPPNDDDAKHGPNCGHIYCKECFFGYTKKNIKETLTYVKCPVSDCKEYLLINENFIPPEFRNQWRETVREAEALYSCRIIECPFLGCLGYLIDDKKGFLIRTCPKCWTLFCVMCRDNWHKGMDCRTNYQWKRKIRSLVDAKKDDDDKGAGDEYSNLLSLLRHFKNS
The following text describes a protein:
Function:
Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
SSRYKSTEAVPIATAARKHTQDYNYWRSLQFPIIVKEYGAVTNVEFQPTEPHHFAVTASSRVELYSKESNEVVKTFSRFHNTAYGASFRSDGKLLVAGNEDTQVRLFDVQGRVPLRIFKGHSRPVHVTKFCNNKQQLFSASDDKTVRVWDISTEQTLNEFCGHEDYVRCGCISTASENTIVTGAYDHTVRMFDTRSNANTITINHGCPVESVLLFPSGSIILSAGGHSIKVWDALQGGKLLTTVSNHHKTITCMTFNHDCTRLLSGSLDRHVKIYDVTNYKVVHNIDYAGSILSMAVSPNDETLVVGMADKMLSIRHRKQCNKEEMKEENLHLSKRKQKSMMRGRNFVPNKDDIVVQHHQKQHLAKYDQYFRKFEHSKALDAALVAHVSTNSPEITVAVLQELIRRDTIRASLSGRTGNKLVVLLKFLCRNISNVSFAPTLLKVCELLLDSCLETIENVPVEVSHLFKRLQNIMHSESLLQVEMTKLLGSMDLILSSSIKN
The following text describes a protein:
Function:
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.
Sequence:
MISAEEALYQSCYCEENVYKLIEKIDDKNGIFAIIISNDCKMIPLWKQKAAKSINGHVLWDYHVIAIEKEKNGSKVYDLDSTLEWSCDFLEYWEKTMNLAEMAQRDTKFRRKFRVIPGENYISLLSSDRSHMLSKNGVYLKPPPEWPLINSHKPSNLMELIRMSEQIENTTVMDEPELFQLFSK
The following text describes a protein:
Function:
Can mediate aggregation most likely through a homophilic molecular interaction.
Subcellular Localization:
Cell junction, adherens junction. Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein.
Sequence:
MISLPGPLVTNLLRFLFLGLSALAPPSRAQLQLHLPANRLQAVEGGEVVLPAWYTLHGEVSSSQPWEVPFVMWFFKQKEKEDQVLSYINGVTTSKPGVSLVYSMPSRNLSLRLEGLQEKDSGPYSCSVNVQDKQGKSRGHSIKTLELNVLVPPAPPSCRLQGVPHVGANVTLSCQSPRSKPAVQYQWDRQLPSFQTFFAPALDVIRGSLSLTNLSSSMAGVYVCKAHNEVGTAQCNVTLEVSTGPGAAVVAGAVVGTLVGLGLLAGLVLLYHRRGKALEEPANDIKEDAIAPRTLPWPKSSDTISKNGTLSSVTSARALRPPHGPPRPGALTPTPSLSSQALPSPRLPTTDGAHPQPISPIPGGVSSSGLSRMGAVPVMVPAQSQAGSLV
The following text describes a protein:
Function:
Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
Subcellular Localization:
Secreted.
Sequence:
MMAFKVLSLLLVSLSFVLMEENGTRDNTKNSRFLNRRYSEGTLASDYSRTLDNMLKKNFVEWLLNRRENRIDNSLEPSKREVKLPALQERNEGIEVGAKEAKECISWLLSNVGRQRLPLPNGLEDWKNILKQEFMSLLISADLCKAMIM
The following text describes a protein:
Function:
Probable zinc transporter that may mediate zinc remobilization from the endoplasmic reticulum under zinc limitation.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MNNSKGWILSLSINAFCVFGASGIYLDKLVNKWFGYEVLDLANSDNALVTGLATSSGILLYSSWASVMQESFHFLEKISMFDTFLVRVFQFCAFFFGGIVFYIFNHFLHKWLHESSQTGFLHDHFSVSDPSPSTAQNHRSPPASCKRLSSCESSGSPSSRVVGSLQGSYCPSGTHLHEGSLLLEDSSARHSSDSVHEYLVKKPSNCDCECHAHFSSFPTHSGTPDDIEHIHSVYTMGIQTALLICLHKVPEGFITFLASTVDTGFMVLVAMSIHNIVEGFTIAYPLYLAWKSRPKAFLTAATLSSCSLPLGSLIAFLVMEAGGIGSSDFLNFLYGIIFAGTAGMMLILSLRVILPEALRHDHSENKRHSFICFTIGILFTLFLEIFDSH
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MEEKGSEAVGVTLYPADYEAVEMVTDQNKEILQQEFTEAQLFLHSIQELERVRIERKKKKQKTETDVAVEKANEVKLEQQDESMEATEVVEKLEQVEQDVEEEEEVIDPRIHYRPMVAELQAAVAELHQLINSIDLIRRRDFLEEMRCIRENTAPKREELEHLVESKSEQVKESSTILLDGVEALAKTVEKESVFFQGITHMLRKWKICAPIHGNIPKPFRAGEPLAVDCSYGSAGSFFAPQTRSIADLAYAELSRTEKGLVRAKTPEDFLARTIQAEMDKLEDTPEDLKILEERNISVLKAVQFSVFCEELFYTLMKEALQNTSKWTDTAYNISNYIVKKHGREEKPAADTNISVLQVLDDEIQLRVNERYHLTIKLVDVKSLSKSKDALSEENKVAVEVLSDTAAQGQEAEPIMDVKMEDPQAPTSSPVKPRRAASISYSTPADSDEAFLTQTCRYTLLLLQQEIRTRHGRKEISRALLYTGSDVSTASGGGLNSTNSGAGGAAGMGPASEMDKHDNTPGTLATVLSVLAHNLLKNEVALYLDEVSSVLAFQKLQVSASGRVLDDGLLQPICDSVRGVYVSPRWKTCAYDSTLSAFDLCVGKNFSTEVLISGARILLQTGIASQREVSGVEGLREFVESTVCSQVALALHRDAASFGLKQSSMNLDRTSVRLVVTGEWDGSCIGEGRVSDSRAVGSIFLEPYFATDGSLAINCLLQAVDVGKLKPVQATLCRSATGEVHKVEWKRIPGLSDAGKMLWLMQKTGVLSAPFKAPIKAKETQLSNGN
The following text describes a protein:
Function:
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
Subcellular Localization:
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Sequence:
MLYPEYPEYDNFNESGALIKVVGVGGGGGNAVNHMVMNMVKQEMGGTFVGESSLTSEEHGRIVFYAVNTDAQALRKSQVQQTVQIGGETTKGLGAGANPNIGRKAAEDDQDEIRKMLEGADMVFIAAGMGGGTGTGAAPVVAKIAKELGILTVAVVTKPFTFEGKKRMQFAELGIKDLSQYVDSMIIIPNQQIQKVLPKNAKLIDAFAAANDVLRNSVMGISDMITSPGLINVDFADVRTVMSVQGQAMIGFGSAVGEPGAGRAEEAARLAVRNDLLEKIDLSNAQGILVNITAGMDLVFEEFNIIGETIGSFASEEATVVVGTSLVPEMSDEIRVTIVATGLGEIAGNEPIQVVRQGLSTQNIEGEGRVNIVPELHRRESVEVSRTASEEYQRPLDKPITDRLEAFKKNNFFNPAQREEN
The following text describes a protein:
Function:
RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
Sequence:
MLPVSRPEGHMSLNYIPTTQSISGTSTGRSSPSDPSANTIIRPPFVSSNILNGNTGSIGSARLGAGSPSHELGARLYSKRAREIQAEEGVSPFWGPPTSGHSTPLRENIPESPSQEGFPDLVPSTSGAMNGPARRTRAGTVPSRFSPVGVLNEANLQQPFVSQSSRPTPSTSPFRPTGMSGIDTGVKPPTTIGGGSTGSLSRLRAGSMPQRTNLLGSAGPFGPSLFSTNWATGRDRATTLTSIRSSEGPASPSQSSFSRDGLTDSDVKTLDYLGLAETPQQARTNFVRPSVDVLLQQQQQQQQQQQQQQTSSLPPLLAELAMIKNNSRIRSYSVNAKEKYADDEELEYESRYSQLPSGAITPSAAATAAQLAATQAQIHQHNLAVQAFANHATVNRPRARTAGILEAPPQRSSIRNYLATPSRLENSFSAADLNIAETGEYDELTEAVQMMHLGGAGGANLGLRPTAEVDENNQDGPTRALWIGSIPVSTTVTSLEAIFSMYGKIESTRVLTHKNCGFVNFERIESAIQARSLLNGKEIFPGAGAVRIGYAKVPGSSNAGTPGVNGAQSSPTPDPNSKSTIPDEEKLSSGSNVPQIPALPDLQPEIVQIVKEFGATEDETTKINASIQQAISYQEFSDEIPPIAEPNQTRMFDAPRLRDIRKRIDNGNCSIQEIEETAIAMLPEIAELASDYLGNTVVQKLFEYSSEPIKERILVPIAPHLGEIGVHKNGTWAAQKIIDVAKTPAQMRMIVDALRPYTVPLFLDQYGNYVLQCCLRFGSPYNDFVFETMLSRMWEIAQGRFGARAMRACLESHHATKDQQRMLAAAIALHSVQLATNANGALLLTWFLDTCTFPHRRTVLAPRLVPHLVHLCTHKVAYLTVLKVINQRNEPEARNIVLKALFFSPGDEVLEKILSDQTSGATLIFKVLTTPCFDESMRPEVVKNVSKVLTKLKATPSQGYKRLMDEVGLSSRGGSRDNHHRDNTSSSEKQQHRPASRQTTAVNYASQPSLERQYSGQFPTMSQNLDNARPIPSEQSHSIPYEPYSVNGVNALNGLGAVNGTGFTQEPMMPLAQQQMQYQAYLAAQSRGVSPGLYQALGNSTYGYPAGSDSLRPMQAQPGQVNSGSMLNQPPYPPQQFSPIMGSAQMYQYPPQFYSQAAPVQGQPSGGRRGRVSYS
The following text describes a protein:
Function:
Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTLGMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRNDSHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPVTLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKALPAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIALLTIYGALV
The following text describes a protein:
Function:
May be involved in protein sorting and cell wall formation.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MDRKANAYSKSVELLSRLEGCPSEKVLLEELRKLRGFIRNDIPSNFFPQLFITDNGFAAIKKAVTKLNFQSLLSLDIFECCLQILGIATSYTILRSWLLSRKHIEAWIELAIRRMFYSFCAIQDDSNISIYAIGTSSKTDSSIQAASPNEDLKSEGAQEIDSQSETVSISSDVDYDEDRKDLKKAKICSAYYLKTRLLLAVLSFAQNDSTFSLLKLVPSLQDNTNASLVELSRVVEAAIQKLSIKPLAFPNVLPQVLLLCPSISIFNLILLHLRALIRSSPENAIKIGYSKTMHFLLTYLFEPPTSFPLSDVSKDLLNEITLHCATFGVSNASTAKVLRTYLKTKSEFLRTWLLKALSHLVAPSFYFNPSTKGYSSIDFTLSSPVMPINGYSVSLWLNIESLMNDDGNYAPTTLFLISDFLKSTLFRLLLDASKKTVVVHIGSSKDTCVVNFSTPITNFFSKIYKDNPSLNPPSWHLITLVHRNEKSSLPNLELYIDGSAVERAACPYPFLSSTLQPLYVSLGPSIGSRNQSTPSTLAPNVAETDALVSENTGAASQKTSKSYKTNDSLKVPPLVPLLIGTTRFFPVPLVSSQIAIISSLGPSYSGCFQGPINDYMTYKASTALTLEIQDSKSNTEDLLHSIQAFSRSPIAFMSCARDYVDIMDLQLSDFCSFSVLETLKKLENQYYSHVYINRAVSSYDKAFSAEQPSFGVSSGSVTPIIMQSISDAIYNIGGSSILLELVGTAETEAELNFGLQVFFSSIEDNWRFSENVEQTHSFEILAQILHSKSHLLVSEETLKIIALMSGVHHTRFKHPLVMNPLLFRYLILDFDLWSKAPNSNLFVQQLGYIVSLIENNDYAGFNVKRLMKMQILKKLLTAMRNCLFHKDLLPILRLLFKVLMTSAFVSENIRSVATYIIYASQATGKSKPIRRSSVSIAVDRSDSNYISIKESGYAICEEFIDLLIKSNGEPSFLRRFSSMITPAWLLFLLRQQDIHYFICGIRLLNQSICSLGSSFLSKFSQKFHGFLILHDNLKDHIHLEELWLNLLFLSLGLGIRSVQFRTDLTYKQKLDFVLKNELDNILPLSEVFPSLFHAIQATLEKVSNVNGKLNSENVAALRYADDTMSFLVTLQTTYSFELTLNYDFSELLTKVVFPFLSPVDTITAEQEMRDLLHNIRQPLPRSSSSKTFGEGIKKSVRKFSMSGSFKRVVTPLGTQLRKDILNDSITDMENTSSFTASFPQSDQALQYFDNFTVQYAEAKDVIKGLLFSILTCIYNRITSGQGFSYSRLLVYLPPSQIEKKSTFFSGILRSTMSKLIEAVKNDKLLLAEPSILANISYIFTKFIRMHLLGYLKGSWLEIVDDLGSLLEEIISRPDFLAKLPKNGRNAAMNMYSCFLDLFLLEVSDLKQTECNAQSDKIIKSITYWQSLLFNSKTYQKDLFSLLWYAVYIMVETTTGVVRLQAVDAWRLLFLHSPGYLSDIAKTCNNDPRFAYEICKTLDNDSDKFVRWLDDNAAEVNQFMLSCFFCRWEDFLKQQHKLADEEASLLQFSRLEHLRKQLAQNTFNENILNESSASYHVWISSLFALECNRFKKMSQDQSDQENFVAAALLSQKNELSHENSILGSKTTSWELDSTEGSERMRKRLMPCLLQSSELDSKLEARSSGARRNRSFDTSVEAPVSLTNEEKQAATLILPSQEETLHDAARSDSNNSMEDEEDDVDEEDKEDKNRTVMRSIESGDSIQDVYNVSRIFGLEATEGILLLGKQYLYLMDNFFLRSDNEIVDVNDNSIIDERDPYLQLLHLQSLSSSGKVRRHISKENNWHWDFIDLSLVLKRFYLLRDVGLELFFKDGRSFLTILSNTKNRDSLYQKLVARAPGADVLSTSHFATSMSRDLGKANGKSNFLSSKLANALSFSTTHPATKRWERREISNFNYLQIVNTLAGRTYNDLTQYPVFPWVIADYTSKELDLNNPKTYRNFCKPMGAQHPERESQFNERYDLLLGLNDSQQQPFHYGTHYSSAMIVCSYLIRLRPFVDSYLALQGGQFDHADRLFYSIEQAWRSSSKENMADVRELIPEFFYLSEMFINGNGFDFGSRQKESTPINDVILPPWAKGDPAIFVQKNREALESKYVSAHLHEWIDLVFGCKQRGDEAVAATNVFHHLSYQGAIDLENIENEFELAAAVGIIHNFGQTPKQVFKKPHPQRGPDFTDTPLGPYLFGRFEDSIHLLFQSCSPIIRICKKVAHIQYDPSKDEVGAFAADYTPLGPNTFLAWGRVDNTVQLISDQLDKQPVMFEELHSEKITHVVACDERTFLTASLDLTLRLWTLSTNKPIKASLKRVLYGHRYRITCVTVCKAFSIIVSGDAGGNLIIWDLNRAEFVSSLSVYKLPIQTIAVNARNAEIAFSTGFYCCVVNVNGKILVKDKLSRIYNENSDENILCSCFYTGANSEWLHKNLFITGHPDGIIRIWEKRLQSNAKLEAEKNNADRPKWRFHLLRQLQHTKGLGRNRVATRQNIITITPNGQARGIFAGDDKGQVFSWMLPDTTSNVHLEKDNTSELCSLCDSRFSLMEWRSQCRACGNSNVCSDCVSMLKDTNIKTCYECYRQMPLCYKN
The following text describes a protein:
Function:
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Subcellular Localization:
Nucleus.
Sequence:
MSGREPSTIYSQPANTGSGIHENTQLASAIDALKHHSNPVRLEDFALSQGLPALLNPNSGLFQRFRSHDRVTYDAKTDLYMYKPDYDLRTPADLVALLKERFLNPGGNGARNSSAAGMRLAELRESYPAARDAIEELGKVEPKEDREVLILRGQRDGAIKQVFWNPLRGKDAKGVDDEFKELWHELKVPDLVDLPKELEREGLSTTDMLDAPISAAQLAANAKNKKKKKGTGARRFKLQNTHLEGVDLSQDFIKPS
The following text describes a protein:
Function:
MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity).
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein.
Sequence:
MAKKNKPTECPAGEKWAVPYADFLSLLLALFIALYAISAVNKSKVEALKTEFIKIFNYAPKPEAMQPVVVIPPDSGKEEEQMASESSKPASQNTETKATIARKGEGSVLEQIDQGSILKLPSNLLFENATSDAINQDMMLYIERIAKIIQKLPKRVHINVRGFTDDTPLVKTRFKSHYELAANRAYRVMKVLIQYGVNPNQLSFSSYGSTNPIAPNDSLENRMKNNRVEIFFSTDANDLSKIHSILDNEFNPHKQQE
The following text describes a protein:
Function:
Required for neurogenesis in the neural plate and retina. Strongly cooperates with neural bHLH factors to promote neurogenesis.
Subcellular Localization:
Cell membrane. Nucleus. Note=Nuclear localization is essential for its function in neurogenesis.
Sequence:
MHQIYSCSDENIEVFTTVIPSKVSSSSRRRVKSSHHLLAKNVVIESDLYPPPRPLELLPQRCERRDTGDRRWLQTGRLQTARPPGAHPTKTPSRPVGISEPKTSNLCGNRAYGKSLIPPVARISVKAPAGAEVAAKGSEHGAVLGRGSRHLKKIAEEYPALPQGAEASLPLTGSTSCGVPGILRKMWTRHKKKSEYVGATNSAFEAD