lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May have serine protease inhibitor activity (Probable). Might play a role in the glial-neuronal signaling pathway that is important in establishing the electrical properties of axonal membranes.
Subcellular Localization:
Cell projection, axon. Membrane; Single-pass type I membrane protein. Note=Localizes to longitudinal axon tracts as well as to an axonal scaffold in the brain. A secreted form might exist (Probable).
Sequence:
MAFPYIWALLPLICSASGLSLPNMTSTDAVVAGGGILPILVAGNPGNLGSSNMSLSGGGGLAGSSTGGQSLPDTGGGNSAGGSPAGGSSGTGGGGSNSGISGNNSAMIQGQKSNQYEKCAGPGDPGPCKQYIYKWRYEPTTNECTNFIWGGCEGNPQNRFGTEAECLFHCIGGPHTLPPFLQSTTREPSTTESSMLLGLPYTQSPAQSPDGMGGAEGGDGTTPVPIEQRGPELTFAETGQGKTFIFAKNNTFIQMDGDIIQTFQLRLCREISFQFRTRLPHGLLVYHNVKNPDRINLDPYALYVIVEKGQLKVVHVFGKHSTSVTVGESLNRDEWHSVMVRIDVHGARLIARVDNSQEEVYLKGLNHEYNYGVSTNLPSVVLVGGLSSEEKLHGVKYITESFVGCIRNVVLSSGKAASDLLPIAPLVATKHENVNEGCSDMCESRHNLCFVGSRCINHYGGISCDCFGTHYEGEHCDIYTATIITLRGASYVSYRIYDWKDRVHSSTRRISLMFRTNFDDSALFYASGESLKHQYIAASIKNQSVHVEMDFGDNVMSTVLTDDLTRGYWHNLTILHEQRTVSIILDQQQKVLELPATASGNMLFDPEIYFGGGPELHKKKGLASHNNFVGSLKYVYYNDISILYELQRGNPKVHYHGVLEAEFVENEVNVIPITYPFATSHIWWPINHAEEFNIKFDFRSSRPGAVLAYSDVTTSAGNGFWEIRLTSDKLSFDLVPDVNNNVTHSTTIKINRATSWHSVELDYKLGEIRFTVDYRHTLSQMYGLTFNIGDKLIIGSSLKSAAMGLVGCIRDIEINGHLIEPRHVVKTERVVGEVALDNCNYIDPCKRPNTCEHGGKCFVKDDRVTCDCKHTGYIGKNCHFTKYRKTCEELALLGFTKSDVYLIDIDGNGVFPPAHVKCDFQSLENATKTIVEHNLPSQVDVRSARESDFSFNIRYREFSPHMLQELISHSLYCTQYIKYDCYRAQLELHSATWFTSSAKNLTVDFLGNVKRGACPCSVNKTCVDPNQSCNCDVKENKWNSDEGYYQDPQSLGITNMYFLQQKDMDDEAQGRITLGPLECVETNTQKYVVTFTTSQSYIEVPGWRKGDIAFSFRTTGEKAILLFQPPIRPHYPSFMVALTGDDQLTFTFTLSTGTTRELVINSHRRLNGGEWHKIWIDYNQYHVRFMINTDYQMLDLLPEEEFGPFEGSMYIGGATFDLLKKLSVKAGLIGCFRGLVVNGEILDIYSYMSVHLSEIIKDCKPSCVPSPCRNGAQCKELWSSFKCVCNNPWAHIGEFCETNINEKALTFINRESFLMRNYLSVGATPVILMHGINGERDVLKGILNQDLLINLRTYDTNALVLYANDHYNNFVHLYISLNREIVFLYNYGDEIVNLTLLDDTLMASLKSIQVAIVRGEQETRMHVNEHSVSIDRGTLLLDEYANKPWSNPEKEVLSPHRPPAPPTEYFQFHVGGYDPANLLRPNVDAPALEGYIGCVRGLKIGAQLIDLADINERNIAPTQEGVLPNCQIKCDAEPCKNGGTCQEHFAEQLSTCDCEHTSFLGEFCSEEKGADFSGESTLQRKFELPGTGRVDYVRLQLAFSSFDLRRANRIMLLMQTEAERSYYLLLAITSDGYLQLEEDRDNGQTVGARIDRNFLNSARHSVYYVRNGTQSQLFIDREQVPLSEFAARVLTTGGDAGSNRVQIGGINSTDSRFAVFKSYSGCLSNIYIQVNGHVMKPLEEYMLFTKSGADNITVINPQGVRSAQCNAKFDVSEQPTQEPMVNVSMIPEPWVEEPPARVPYIPRFVYDENKQEDSTQVVFLTLTSVFVIIVICCLLEVYRSHLAYKKRIERETDEDIIWSKEQATKMHESPGVKAGLLGGVTAGSGNGLPPYTYKALPQEDKKPGNGAPLVGILKNGSATPSQPGTPTALSKNGDIASRIEEEEEEEDEAPAQKAAEKSGENEEPPAKDTTASEIKESQAQPPEQLAKDTTDASAAPKASKETEAQAEPSEPSSQLNSAQNGQLAQMEQAARGDEVQVPSLPHPIQPPDAIFMPNLPQKAQQRQPQEHKSRHKATDDTEAPKQQQQQQQQQQSFDVATNANGSSLPASRVKNPEEPGGKSPLVPMRQHHSKVTRPPPPPTLFLENSLLQRQFANPISYLGGPRLQPRSNRTSIDSILSLD
The following text describes a protein:
Function:
Major secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods). Plays a role in the morphogenesis and autolysis.
Subcellular Localization:
Secreted.
Sequence:
MASNPFNYCLLWLVAFIGLAAPLALSFSTGNGTGCRTQSNIVAATEHFGEVNMEGGYKSIAYFVNWAIYQRNYHAFDLPADKLTHVLYAFADVRPDSGEVFLRVAYADVDKHYPGDTWNEPGNNVYGCIKQLFLLKKQNRKLKVLLSIGGWTLSANLTQGTSTDAGRNTFAQSAAKLLLDYGFDGIDIDWEYPQNEVEAQAYVSLLQKCREALDRAAGPNRRFLLTIACPAGPNNYSKLKLREMTPFLDFYNLMAYDYAGSWDSVAGHQANLFPSNGNPSSTPFSTIQAINYYTQVGGVPPSKIILGMPLYGRDFLSTNGPGTPYSGNGAGSWEHGVWDYKALPQPGATEVFDQQAGASWSYDAGARTMVSYDTVTAAEMKVNFIKEQGLGGGMWWEASGDKGGKAANKADGSLIGTFVEGVGGVNALEQSQNNLDYHESQFDNLRAGFP
The following text describes a protein:
Function:
Could be an enzyme that inactivates 6-azauracil by modifying it.
Sequence:
MTVEYTASDLATYQNEVNEQIAKNKAHLESLTHPGSKVTFPIDQDISATPQNPNLKVFFFDIDNCLYKSSTRIHDLMQQSILRFFQTHLKLSPEDAHVLNNSYYKEYGLAIRGLVMFHKVNALEYNRLVDDSLPLQDILKPDIPLRNMLLRLRQSGKIDKLWLFTNAYKNHAIRCLRLLGIADLFDGLTYCDYSRTDTLVCKPHVKAFEKAMKESGLARYENAYFIDDSGKNIETGIKLGMKTCIHLVENEVNEILGQTPEGAIVISDILELPHVVSDLF
The following text describes a protein:
Function:
Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation.
Subcellular Localization:
Cytoplasm. Golgi apparatus.
Sequence:
MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPPRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIRESKRNSRLGFLYDLDKASNTPFPQQVKSIERFLRRLEFHASKIDELYESYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLESELEAQLGEFHLRMKGLAGFARLCVGDQYEIYMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFHRAETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEAADLESLVRGPSPPACPDPTHGEHPARVPPVLDAGHSATNPTLSTTGPAPSAHLGSANKTINSSSPELPTQTTTGSTYCAMSPTHSAPSLIHCTTASTHKTVVSILTTTGPTPSTTGPVQTTSPTHKPVLSTLTPAAPTPNATDPVQTTASLSHTVTNLTHTVTSATNKPMASTLMTAGPTASATGPVQTTTSPTHTTTSPTHTVASPTHATASPTYTTTGPTHTTASPTYTTTGSTHTTASPTYTTTGPTHTTASPTHTTTGPTHTTATTTPKAKMSTNTTTPNAKDPVQTTSSPTHSVTSPTLITVSSSTFLDFAKLSSPSANTDPPHLGTDPLSGSYLASTPCTQADPISPSTSHPSPACSSWEPLTTPSPDPSEAIRQSPSLPPSPLAPVPQHPDPKVARATPAPVPGAAGGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDEDNDSPGDRPPNSLAPGAEDSLDSPSARPLSTECPALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEAVCELSRRWEIPATSAQEVVQFSASRPGFLTFWDQCTEGFSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCVKFLEDALGQKLPRNQAGPGEQLTVFQFWSYVEALDCSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPHIFGPGSMASTAF
The following text describes a protein:
Function:
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
IHPTSVISGYRYISENLIINTDELGRDCLINAAKLGVQVVITDPEKLDQIRYFVEAGAMAVRSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARAFHNEAQVNPERKFATEAAITILR
The following text describes a protein:
Function:
TIR-NB-LRR receptor-like protein that contributes to disease resistance induced by the Pseudomonas syringae type III effector AvrB. Acts additively with RPM1 to generate a full disease resistance response to P.syringae expressing this type III effector.
Domain:
The TIR domain mediates NAD(+) hydrolase (NADase) activity. Self-association of TIR domains is required for NADase activity.
Sequence:
MDSSCFLVYRIFRFRKRNKNISSSLSSSSPPSSLSQNWLHPVFLSFRGEDVRKGLLSHIQKEFQRNGITPFIDNEMKRGGSIGPELLQAIRGSKIAIILLSRNYGSSKWCLDELVEIMKCREELGQTVMTVFYDVDPSDVRKQKGDFGKVFKKTCVGRPEEMVQRWKQALTSAANILGEDSRNWENEADMIIKISKDVSDVLSFTPSKDFDEFVGIEAHTTEITSLLQLDLEEVRMIGIWGPAGIGKTTISRVLYNKLFHQFQLGAIIDNIKVRYPRPCHDEYSAKLQLQKELLSQMINQKDMVVPHLGVAQERLKDKKVLLVLDDVDGLVQLDAMAKDVQWFGLGSRIIVVTQDLKLLKAHGIKYIYKVDFPTSDEALEIFCMYAFGEKSPKVGFEQIARTVTTLAGKLPLGLRVMGSYLRRMSKQEWAKSIPRLRTSLDDDIESVLKFSYNSLAEQEKDLFLHITCFFRRERIETLEVFLAKKSVDMRQGLQILADKSLLSLNLGNIEMHNLLVQLGLDIVRKQSIHKPGKRQFLVDTEDICEVLTDDTGTRTLIGIDLELSGVIEGVINISERAFERMCNLQFLRFHHPYGDRCHDILYLPQGLSHISRKLRLLHWERYPLTCLPPKFNPEFLVKINMRDSMLEKLWDGNEPIRNLKWMDLSFCVNLKELPDFSTATNLQELRLINCLSLVELPSSIGNATNLLELDLIDCSSLVKLPSSIGNLTNLKKLFLNRCSSLVKLPSSFGNVTSLKELNLSGCSSLLEIPSSIGNIVNLKKVYADGCSSLVQLPSSIGNNTNLKELHLLNCSSLMECPSSMLNLTRLEDLNLSGCLSLVKLPSIGNVINLQSLYLSDCSSLMELPFTIENATNLDTLYLDGCSNLLELPSSIWNITNLQSLYLNGCSSLKELPSLVENAINLQSLSLMKCSSLVELPSSIWRISNLSYLDVSNCSSLLELNLVSHPVVPDSLILDAGDCESLVQRLDCFFQNPKIVLNFANCFKLNQEARDLIIQTSACRNAILPGEKVPAYFTYRATGDSLTVKLNQKYLLQSLRFKACLLLVEGQNKWPNWGMNLVTSREPDGHIVLYTPSSHLQGPLLMENLYTFEFELVVTSSEFVLEFRADRYKCALGRFDKFGVHVVWCHLDQYESKSPSCKPFWRDFPIVISNGQNILDAILKTPMPSINQ
The following text describes a protein:
Function:
Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. May be important for freshwater adaptation.
Subcellular Localization:
Secreted.
Sequence:
MMCKALVFAVLLLAVPLERADSRALRTPVDAIQFVEQFLEHYNDLLNIDDLENQTGDQLESPQPLSSGLKVAEYPKWVDVPSQNDNTWFRLLRGALANRKRALPDRAKRGWNRGCFGLKLDRIGSLSGLGC
The following text describes a protein:
Function:
Functions as a component of the ISW2 complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW2 complex is involved in coordinating transcriptional repression and in inheritance of telomeric silencing. It is involved in repression of MAT a-specific genes, INO1, and early meiotic genes during mitotic growth dependent upon transcription factor UME6 and in a parallel pathway to the RPD3-SIN3 histone deacetylase complex. DLS1 is partially required for the ISW2 complex chromatin remodeling activity and is not required for its interaction with chromatin.
Miscellaneous:
MISCELLANEOUS: Present with 3390 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MNNETSGKETASAPLCSPKLPVEKVQRIAKNDPEYMDTSDDAFVATAFATEFFVQVLTHESLHRQQQQQQQQVPPLPDELTLSYDDISAAIVHSSDGHLQFLNDVIPTTKNLRLLVEENRVRYTTSVMPPNEVYSAYVVNDTAPKPNIVEIDLDNDEDDDEDVTDQE
The following text describes a protein:
Function:
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGIIVLILGIFLDRISKIWALNTLASGKDIVVIKNLFTFSYLENRGAAFGIFQNRLIFLSLITAIVILGVVYFIVKYKPTSKLLKISLSLIISGAIGNLIDRIYYKFVVDFIMLHYKDVYYFPTFNVADMLVVIGTVLLAIYILKEE
The following text describes a protein:
Function:
Probably not involved in maintaining the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP, RMEV, AVK and HSN neurons.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MKNLLLITFFVVSTVTALGGRGSKSALVLVAARSSENHPLHATDPITIWCAPDNPQVVIKTAHFIRSSDNEKLEAALNPTKKNATYTFGSPSVKDAGEYKCELDTPHGKISHKVFIYSRPVVHSHEHFTEHEGHEFHLESTGTTVEKGESVTLTCPVTGYPKPVVKWTKDSAPLALSQSVSMEGSTVIVTNANYTDAGTYSCEAVNEYTVNGKTSKMLLVVDKMVDVRSEFQWVYPLAVILITIFLLVVIIVFCEWRNKKSTSKA
The following text describes a protein:
Function:
May be involved in the transport of sterols.
Sequence:
MYGEGLYCAGEDLLGRCARGKDSLERLTSVVAWSISTTRPPIFGFAPYNPVLGETHHVSAGSGGLNVLLEQVSHRPPVSALHATNAAGDVRLVWCQSPVPKFHGASIEAAVRGRRELRLPRHGERYEVDCPNLLIRLLPAPSVEWSGDVRVVCAESGLEAQLSYCRSRSFLGFGGDARCVRGRVFRSASRDETIYEIDGFWDRTVSLKDVSTGEVSVLYDAQRAISKLTTPVVQDHKGLAPSESAVVWGEVSDALLKKDWEKARQAKRRVEDEARKLAKERNEKGEVWTPKHFSLSQNKNGEWECWPLEESVPPAPIVVPS
The following text describes a protein:
Function:
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Sequence:
MSRLFVKRLPTGSFLMLLLYIGLLLSAIAVAYSTYWNRQLLNSLYSELSVRDKAQAEWGRLILEQSTWTAHSRIESLAVEQLRMRVPDPAEVRMVAP
The following text describes a protein:
Function:
Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPVSDQAFVTLATNDIYCQGALVLGQSLRNHRATRRLVVLVTPQVSSLLRVILSRVFDEVLEVKQLDSADDVHLAFLKRPELGVTLTKLHCWTLTHYSKCVFLDADTLVLANIDELFDRTEFSAAPDPGWPDCFNSGVFVFQPSLETHGLLLRHAADHGSFDGADQGLLNSFFSSWSTADIHKHLPFIYNLSSNTAYTYGPAFRQFGSRAKVVHFLGSRKPWHYTYNPETGSVCTDGAGALSQHQASFLNLWWKTFHRGVLPLYETVLEEGEQTPPGHTAHLRGAGSPSACSGPTAEGPGVSSMPSTEEPGANSAEGPSQPRPARDPLERTVVVSETPPSPEAPSAEDMLGWPEVEASAGELGDPVSPASPQFADLTETPTGSQPADTAEGGPSEESLEPSPVPPVDVTRDPRLQDALEVALAVSVSALSIQEKVKAPSPEEERRKWEEGRMDYLGRDAFARIQEKLDRFLQ
The following text describes a protein:
Function:
Responsible for methylating the 5'-cap structure of mRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MYDPARDSWEERDGDEARSCRGRLASDQPHAVFSPPEQIHGASGENNNTTDLQQHPDPSSKTTASAEVLYAESQPAQPTTQTPPSVSTRIQSPVDPAAQKASNPQSLTSTAQNQLNKSNTTMENTSGSATPKPRADPSDKPNRPVQVASPTDQNGSQGDKKRKLPAEENASEKSQPAPDRPVSKRKRMEERHQKLRKRGRTPPSAYSRRDAEETSSAADRNGPTYRSTSPLPPPRSPTPEDQPRQRKRPGGGARMGLVDRETLRRRQEERERAQVEEAMRASQSRGVADVVRQHYNAVPQRGREWRKTESKIKGLRSFNNWVKSTLIQKFSPDEEFLARFNGTKEWAEDGGVPPVEEKRLLVVDLGCGKGGDLGKWQLAPQPVDLYVGLDPAEVSIVQARERYNGMKSGRGNRGRRNPIFHAEFRPKDCFGEWLGDVDIVQQVGIDPNVGPGGSVMSSRWGGGGFDVVASMFTIHYAFESEEKARQMLRNVAGCLKKGGRFLGVCPNSDVISARVSEINAKKKARQAQAKKEKSDEAPEDGEVEEDDGKVEWGNQIYRVRFPITPPEDGVFRPPFGWKYSYFMEEAVEEVPEYVVPWEAFRALTEDYNLELQYRKPFLDIWRDEKDDPELGPLSERMGVRDRVTGKLLMTEEEKEAASFYHAFCFYKV
The following text describes a protein:
Function:
Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. Plays a role in neuronal migration.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MSTEIVAKKLLAELVKKSGLTYTTDNIVTIFLNRDGKYSNKRLATLLAQLFKPFPNGSKYVDMYAPANTKESYPALVMVLNRFANDLKTAHAEKAAATVASAAATVAAQEQSIKSDTSGTAVPTVSSEPVHKRVSLFESPPLSSTRIIPDQVTPENVQEIKEKLVQATSNPASNRLSSSTSLPPGSMMAAHHHHNYPSLSRPAGFEFSHRKAPIVSWNFNYDELYPLQSKANVAAIPVASQEPIVLKEVLNCLIGIKGTLITPRKGATTLDPDGALAVEFQLSNQLTESCRDMVVEVLPLAANYSAVQSFIEGASVTEGGVVLQALRSVLKTIMTDYYLSIAQLDDLRCRRGLSLQRLIQFLKPVYPTMEELAATVSEIRRSNARGGQVLSLLHDRITAKSGTNHAQKVLVHLVESAAAPFMEMLELWIYRGVINDPQQEFFIDHSSMELTENELVDYWEKQYTIRNEKVPCFLAKHADIILRTGKYLNVVRVCGGAEFQPGNANGGGGGGATTTTDLLNASSATARTTTAVKRLQYAHFDQSYLDEIEEAYNFASSSLLNLIMNKYDLMGRLLSVKRYFLLQQGDFITEFMDAVEEDLRKSVDTLHPIRLANLLDVTLGLSSAKYDEYHDDLKTMLLPYGIVTQISKIVNNEDAFVDTLSDTSQLKGVECFTFTYKAQWPVSIVLNLWTISKYQMIFRQLFYLKYVERILCRVWIANNETRQFAPNPAKLYRSAFTLRQKMLIAIQSFESYMMIEVIEPNWHIFYQNMKQVKNIDDVLNYHQDFLDQCLKNCMLTEPDLLKPIINLCNICIKFCDFLATATTMAPTETFSERVEQFRHDFTDQLMTLLRKIADVATLSTSERFINLIYRINFNSYYSETNEN
The following text describes a protein:
Function:
Associates with the SIT4 phosphatase in a cell cycle dependent manner. May be directly or indirectly involved in SIT4-dependent functions in budding and in normal G1 cyclin expression.
Miscellaneous:
MISCELLANEOUS: Present with 11200 molecules/cell in log phase SD medium.
Sequence:
MSGSFWKFGQDFGSQSPLAKLLNRAFIKIDDKPTSTEAGKIDSNSTDESLESNSFKSEDEEEEYELPNREEDYKAYKPNLSLLNDLLDDEELYTELMCSNFKLLVYLKYPEVLSKLIDYVRNSTILESNIDRVTSEDRDLVRGEDKDTTEDFENAKADKKNIDGTFEEKERTRSGEEEELENEENDSASEDTRVTLPHELEEHDDTRRARIAAEILSADVWPISSALIENEGLLAKLWSILRLPSPLSIEASTYFMKINERLLDMNMDGIIEFILKKEHIVDDFLAHIDNPPLMDFLLKVISTDKPEISNGVIQLFKKQNLVPKLIHLLDPVFDSCTQSAAGDFLKALVTISGNCPNEITSSIGPNELTRQLVSPNMMKQLMDIMLKGGNSLNNGVGIIIELIRKNNSDYDTIQTNYTTIESHPPTDRDPIYLGYLVKMFSEHMADFNKILTEKKIPLLQTSYGTIEPLGFERFKICELIAELLHCSNMTLLNEPSAYDIVRERDAERERIFNSQNYVDSNDRSELKENEDDNTGDADDEVEDDTNQVESANTSIDGEEVIDKLNSLQIETNKVNQNMNNEEQHSLMPDFNNGDFKDEEDENPFEPQYSDVILDSSDIEKNFRVSPNVGDQLKISLQDTRVIDTMLEMFFHFQWNNFLHNVVYDVVQQIFNGPLKIGYNRFLLDDLLINIRLTDMIINGNNECIEYEKGHDTRLGYMGHLTLIAEEVTKFTAYIEEMNITFENTEVMSSLFESKWIAYTEDVLEDLKEKYNAILGDIAEEGDMLQDEEEDAVYDKGERTMGTVDDYINDIMQMDNVRCQEEEEDEGEGYVSFDEDEPQEYRNGDSVRSKESNSSEGKRDQEQLYYEYVNEDGTKTRLNFNPDSDATEQVPGEVNRDHKIPLKLKRSFTDACKSETIPNNTVNAKEESVFQFSNELSDGWESSPSNSIPKRASPSKNGMNSPMFQHQFELHSPTDEFGGHKDEILSAEGHDYDIDEYDELSDDSDEEYDNCEDEDSLDYADSAAYALCRSKSKDKISWDEEEQARLMGVVKFNSEHYRD
The following text describes a protein:
Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Sequence:
RLQQHAKLTDKEISSLPQETRVYEGVGRMFLLQPIPTVRENLKTKVESSDEKIKKLQSNKTYLERNVKESQENIREMIMQKKAAS
The following text describes a protein:
Function:
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Subcellular Localization:
Secreted.
Sequence:
MSAGQTNSVISQPGCPWQRMWLWKHHCPEYCEQHWSKCGMRMLLLTFWMLTSLISSIHAGSFSKAYTFFRSHQQNKMADIQSTYSHNECGLRPSFESFLWTGKRITSGKYAKAGEFPWQVSIQSNGRHICGGSIISALWILTAAHCFADGVPPDIKIVMGAVDLDFPLEVREPSSLILHEGFNRITLKHDIALIMLNYPIEFSDEKIPICFPYMDDISSWQHCWVAGWGMMGAVSASHMLQKAKMKLVSREECLDQIPQLPKDMLCVELQQGSCQVESGGPLVCSYRNTMKWFQVGVISWGDSCAAKPYHQFYTSVYNYYEWIKTETAMIGKPFLIEGMSKDTVSTTEVYSEAKAQLVFLESAVLLFASLVAIGLL
The following text describes a protein:
Function:
Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Postsynaptic density membrane.
Sequence:
MIYGRSLFHIVASLIILHLSGATKKGTDKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGVLKPLPVCEFEMGGPEGIVESIQIMKEGKASASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCNGLQNCVYPWDENHCKEKRKASLLDQLTNTSGTVIGVTSCIVIILIIISVIVQIKQPRKKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVADDFENYHKLRRSSSKCIHDHHCGSQLSSAKGSRSNLSTRDASVLTEMPPQPVKPLIPPMNRRNILVMKHNYSQDAADACDIDEIEEVPTTSHRLSRHDKAAQRFCLIGSLSKHESEYNTTRV
The following text describes a protein:
Function:
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
Subcellular Localization:
Nucleus.
Sequence:
MSGDMSHDNDNLPSSRKETILNVKMAKEVENFNGCYCLVSTNPRYKGWTYIGYTVDPKRRVGQHNKGSKFGGAYRTSGKGPWDMVLIIFGFPNEITALRFEWAWQHPTKSRRLRHIPRKTGKETAFQYRFRVVSNMLRVGPWCRLPLTVQWLMQEYKQEFDVRLQPPSHMPISYGQVTSTKVGGYGNPRRMKKRKGKKDKSSDSQNLSEEDDDVEAIPSSQTAGKRCIICGKRFQDDETMLTCLYPSCKAEYHMICVSKRFLKNDPDQLLPIEGSCPSCKEVVLWGDLIRKKQGCYAKLAEISEEDESDHWAEDLRST
The following text describes a protein:
Function:
Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor. Thus, can convert bicyclo[3.2.0]hept-2-en-6-one into the oxidative lactone products 2-oxabicyclo[3.3.0]oct-6-en-3-one and 3-oxabicyclo[3.3.0]oct-6-en-2-one. Is also able to catalyze the sulfoxidation of methyl phenyl sulfide (thioanisole).
Sequence:
MSIADTAAKPSTPSPANQPPVRTRAVIIGTGFSGLGMAIALQKQGVDFVILEKADDVGGTWRDNTYPGCACDIPSHLYSFSFEPKADWKHLFSYWDEILGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFTADGREYVAQFLISGAGALHIPSFPEIAGRDEFAGPAFHSAQWDHSIDLTGKRVAIVGTGASAIQIVPEIVGQVAELQLYQRTPPWVVPRTNEELPVSLRRALRTVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNIRRSVKDRELRRKLTPRYRIGCKRILNSSTYYPAVADPKTELITDRIDRITHDGIVTADGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVDRWNREGIGAHRGITVANMPNLFFLLGPNTGLGHNSVVFMIESQIHYVADAIAKCDRMGVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGKNTVLWCGYTWQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN
The following text describes a protein:
Function:
Involved in trafficking and recycling of synaptic vesicles.
Subcellular Localization:
Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Early endosome. Golgi apparatus, trans-Golgi network. Late endosome. Membrane; Multi-pass membrane protein. Recycling endosome.
Sequence:
MKEGKVQPQKSLPIRIYELWPNFKAWCAAGDPPPQTQVKSLYLMVFLLVFGITTGTIWILSTFFNYFQGSIEHTWIFLFASFITLLPGVYALDISYHCWRRHRGYDWWIIPHFE
The following text describes a protein:
Function:
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MASSYLSLAARLSQCWISPWSLCCLYILMQFFLFTKDLNTKIGDFVNDEQATCNYIQEKVDILLDSPSLIANAAVRVAKDGIQSTVKIILSGISDSLIAAENVFIFFIEFSYGTYLCLIQLAIDGILDAVADVGEEIGTAVNDTLHAIADEIEDTVSSLNEVFQSAEDSLEKVASWLGEDINLPNVSIPEIQSLRNFTLSSSYDTEFEKLKAGVNFDSAINATKAAISKPFSSARNLILEKVSNYSFDTSMVSSPNKTHVVVCSTDDLTAISSFILSSIYKIRKVVIISLLIIIAGLFLISSIYEIWKWCRIRHKAFLLDEHIRSNKFEDTRDLISYIESPISWNLKYFISALPLPCFLSVQLRWFITYIFHPPAAMILFISCTSFISGILQLVLLNNIREDGSVISALAQNSFHKVESALANVSVAWANSTNQIILKNQENINNNMFGSIHNTTLSLNSTLNTFMNELNSSMTSAFGDTFLASTVQNVMNCLLYRKIENFEEVLTWVYNKSHIELPLLPTDILSKSIDNQTIYSSLYSSLNSSNSTVSFSGIFDRVEKSVISELNFSFLFFLLWLLICAFGLIGVLSSWLKSLFLSLLDLVIPNPKENITLPVQSLAFPVTKSCRPPPIPPRESHVYDFQNFQYEEDDCIDYKRSLGLISLSSDLAIDIPISPAIISDIQFNSITTESEETTYLLKEKQDRY
The following text describes a protein:
Function:
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MAAVQALPLSIDQNTEASGSQSHTNTRSPVTENTMGSVSSLISGRTYHDKQCRASEFSNKCRKPTNMPNCFKQQEGLLKTNYSSQDFLFNGLPTKKPSTTTSGNNGNYVYVNEDFKEEWHDARVPISPSSDAEDIREERSINGNIRGPPPKLIPISGKLEKNVEKTLIKPTAFKPVVPKKRNPSLQYLVQRNGGPGLSESQSSLNLLFNGNSAGIPEKHNSLSCRNIAHSGTMSDSGRTSLSSLPTSNTNCSHQLDSVSVSMGHINLDNHSNLNGYSDRASRGRTRPSNSDSGRSSSSKSTGSPILNDEILIRELEEKLKDREMELQQLKENLDENEAAICQVYEEKQKRCEQEMEELRQSCALKMKQAAQKAQRLQQVLQLQIFQLQQEKKKLQEDFSQLLQERELLEKRCASFEREQTEFGPRLEETKWEVCQKSGEISLLKQQLKDSQAELAQKSNEILLLRSQFREARCDLQISEEQVQELQDTAHTKTLEMEVCENELQRKKNEAELLREKVSKLDQEVASLREAAVASLRHGLCFCHEKEDPFLLYESDEAKAQRQNADNLQGLQQYVERLREALASERSRYQEQAEHFEDERRKWQEEKEKVIRYQKQLQHNYIQMYQQNRELERDIKQLTVELDAREFNEFDLHGAEIHFEEITATEI
The following text describes a protein:
Function:
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. This subunit may anchor the endonuclease complex to the nuclear membrane. Probably carries the active site for 5'-splice site cleavage (By similarity).
Sequence:
MAKRVAGSKRYVHPLPIEPVVLPPLIAHNPLSWVYWVLAYVTSSNQLPRKIPLEVGADGRYTVTGREQMQYLWEHGFFGTGQLSRSEPTWQARTVDRLQLDTEGIAGHKLEQVTQLRRKQRLEFKRERASFERKRLELRRQGVLESEILEQERLWLKQLRDRELQWEASTGDPSPVRAEDAEIIAEDGASVLPIEKLELMPVEALFLTLALPVLHADAPAILARTLGPQPALPQIERLCRLYAAYHHYRSHGWCVRSGIKFGCDFLLYRRGPPFHHAEFSVMVLAPDERHDYTWYSTVARVVGGAQKTLVLAYVARRAAADQLAALWHARRYMEAFALFEVHELVYRRWLPGKNRE