lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MINRHCLIEHKIPTSVCSQVHQSVHTGVRTFLCPYCPLTFKWSSHYQYHLRQHTGECPYPCDTCPKAFKNSSSLRRHKNVHLGLKPYTCSVCNKSFTQSTNLRQHMRIHTGERPYICGECGRSFTHSSNLALHKNSHSSLNAGQKEGKKGAEGGKRNEIVEVIVNSEEVTSSMLTDMVGFVSQEGADGVGVGMEEVFLSTAAPGSNPGLLPQLTLTPSGEAVCTTRAIGTEVHLSTGTGASVLLYSCGSCSNTFSTRRQLEEHQAIHMAPEEHRASGEAGQEAGMEVGDGLVGAGHLLADFEEVVETTSVAESGQSSEVLLGLSDGGSTVCPEGVATTQAQFDLLQSFTEVTQNSSAAQPETGTTWAGLSCGYCNKTFKTSGGLNRHVSLMHSLSSQSRSQFSCSACDRSFPLLSSLLTHQHSHTPEQRLLAEAEAEIVCPPSLSLSLPLPSSPGQGDKQQEAQGELHVNIIAVGQEQEEQSAKPTKPHKKTGSSKSTPAGERPYRCLECGKAFKGSSGLKYHMRDHTGEKPYRCTECGKSFKRSSLLSIHQRVHTGVRAFQCPHCPLTFKWSSHYQYHLRQHTGERPYVCKECGKSFKNTSCLRRHSQMHSGLRPHTCSICSKSFSQTSNLKQHERTHSGERPFQCTHCTKSFTHSSNLQLHLRTHSLRKDYKCPYCSKEFVMHSYLQRHIRTHGSDVALPDGGGKDGMAVKANMGGVTTTTTLLNPITLKASDNSLIVSQPALNIPPNTSQNYFMIQTASGLQLIPLSSPTPVSPPPPPPPPPPQAQSQNFLLLQCPLNNGSQSSLILVPAASNPPPAPDPQSLPVLQTIQTFQPVVSQTQTQIPQFPAVSQQQQTRIIITNNNNNAHPPVPITTPSVLASSLLTKPILGRSTRTARGRRGRKPKAALQKSATTPVTPPVGGAVPVTNCEVESGLLPEPAASAAPVSSSSTLTLVSSCPLSASSSPVAPTLSQSSTSGCPLSVSNITPAGTAASAPVCSAVCPEREAGSSAEQMREGEGLIGKQLVLCFDNEEQAKDGVSLEQAGESYVLRFEGNEPGEVFDDVVGGGRHSLVLQFKTDGQGEAEKGGDKGGMMSLLQEWGEEKQGECQAGGEDSQGESFVLHFHTETEDSGPSSASFSQEQNNNLQLPCIPNQSLVPLDGQEVVFELGSEAKRAQEAQEGMQMIALIKGEGGMVGKGGTGCNIAGDAVSEEQAMGSIFQLEHGDEIVIIEVSTSSLREGRVEAEGEVAHGGEAKGEGVMADSKENPAEEHDPSECAEGQASAEDTSNEDTISNSKE
The following text describes a protein:
Function:
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by xrn1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
Subcellular Localization:
Cytoplasm.
Domain:
Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex; The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with ppk26/pan3.
Sequence:
MDAWKEITKTTENDGVSTCSLSSIAFDPYSELVWTGHKNGQIKSSFGPSLTSYTQFIGHEGPVHQVLPQERGVFSLSSKSLRLSNRKGTIRWRYQDSDCIDYRAMFYQSRNNPEVVIGGYHQKLTVVNAERGISIHKDKNVSDIFIMRRNRLLCCGSTNGEIILRDPNSFQPVNKVVAHTGTISDIDTSGNLLLSCGYSLRHGTYMLDPFVKVWDLRNLSSLVPIPFPAGPTIIRMHPKLSTTAVVCSCSGQFHIVDTGNPLDAKLMQIPLTSYLTGMDIASTGDAMVFTDVEDNIHLWSPLENPSFSDLKLPIQLPNTSTETVQLENNDPLNSIGLPYYKDELLSSWSKYLIFDVGKPILDSNLLIAKQISENSHPVPQEIKSFHRNQIIEVPWLNRKLISEGATPKFHSERQKDIMSGNDIEGSASYFEEIEDTISGPDSIPKFYQRPVIKYSKFGIEDFDFGFYNKTKYAGLETDITNSYCNSVLQLLSYVPSFSKAAISHSLGPCDLMECLLCELGFLFAMLKESTGRNCQATNFLRAFSNSSFAQSLGIVFDDYSDGTFPDSFVIQKFTKFMLTEISRIADYEDKKDGTSFPVSFLLKSFCIPEMQTYRCGICGITSQKIKSSLYIIDLHYPSQQLESILSFEWLFKMSLDRRVDLPPGWCEYCLAHQPFLLRSFIRSLPDCLFINTQVKHHEHWKLWARKNWLPKKLHLRRVNDTMQCVSQKISNLDKDQQSLSVYVLRGIIYEIRQNGEEPHFVSTIRVSDNTSSDNPDDNRWYIFNDFLVKEVTEEEALTVHGPWKIPIIVYYEKLDTKIPQWDEVSDYTLLYQPYSLNKNPPINKIQPLTTDEMLYPKMLVGIDSEFVALQQEETEVRSDGTKSTIKPSKLSLARVSVLRGEGPNKGLPFIDDYVATDDKVTDYLTEYSGIHPGDLDPDRSPYNVVPLKVAYKKLRLLVNAGCIFVGHGLQKDFRIINLLVPPEQVVDTVDLFFLSSRQRKLSLKFLAWYLLDEEIQLTEHDSIEDALTALKLYDCYDKLKSQGKLEETLDNIYEVGRRFKFRPPSVASMSLEDRNSYGDESVISNQTN
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Sequence:
MRPKRPASKFYAVHRGRQPGVFRDWPACRDQVTGVRGARWAAFRTLHDAEQFVRSGKRAAPAAPAAPAAPAAPAAPAAGRAFYGVHSSNPAVPSAVFDTWAACQAHVHRQRGVAFRKFPTRELAQNFAHGTAAHDWALLGSSPAEFARAHKLPPPPAPFSARSVVYCDGSALANGSARATAGIGVYFRDEPHLSLSEPLTLPPYTNNRAELLAASRALELIWRNLAAVPAAAPRALYVLRTDSEYVVRLLSALYRAYDSPAALAAVSNGDLAVPLVQNYLRVKHWYLLNTACFHPPAEFALEWVRGHDNEPGNEEADRLAREAAASV
The following text describes a protein:
Function:
May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression (By similarity).
Subcellular Localization:
Secreted. Apical cell membrane. Basolateral cell membrane. Cell projection, microvillus membrane.
Sequence:
MGSVWGLAVPLLVFCWKVGVSVSSPGLDISRSVPLVTTNNMEVSTFTQRDRPSSERAFQTTNLIQYVPLDTQTLSTESASNALSATSISSEVNSRDTQTTSFVTKTRKTHTTTPAASSLEAQTTSPNLSTLNIQITSPIASSLDAQTIFPVSLSLSTQTTSPAPSFLDTQTTSPEPSSLTTSPAPSSLITSPTPSSLTTSPAPSFLDTQTTSPAPSSLTTSPAPSSLDTQTISPIELTLKTQTISTVTETRTVSIRIPSDLTVMHTIPTETLAPSNSPRTGMSTVQTGTVWDSIEAVFDTLCTDDSSEEARKITVDLLTLAHTSTEVEYLSSESSSSSDSSAGVLSSSRVLGPDSATPAKGLVAFNITHIKLSNCITEIETTITISGAPGASLSPTEATAALFTSEILTLPPPTEAKPIFPETTSLSGILSTAGTPALATTLEGTVSTSAITESETAVAQTLTSVGTSVTVRRNPLENTSTLSIETQSHTEVLGTITVPMVAGSTMGEAASFVSFTALDSSSLSVVVTTESSATSETLTTGNTTNSSFLTESHPPFSIYSTTASTSKNPNITLTKTTASPKPPTHPTTSASTAWIRKTTKHDPGEDGGFLLVRLTVASPKDLTEHNAREKLMNQLRRELHARMPLVHMSFLSIRRG
The following text describes a protein:
Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MPQLLPFYFVNQISFAFLGLFVLLFVFSKYILPAFVELFVSRMYITKL
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MVEKQFNIDLELNDTGHIDPFLQDEDKLKLEELIPRILFERKSFLNVTEDSLRKEIDNSLKISEEDALDTEESREDTVEADQQEVFNKHKFELSKNINNALNETQLSLDFVSLLISSVKPSLAKSTISPHLSKFVKPTSLNSDRLGQDSNDNQESKATDSFGQGWKLESLGKITDLFREASTNLNDQVIKERRYWNMINLVLANDEVLFRMRDPQNNARAIGVKYGYGDSGSNFHDQGLALLRKDNQTGEISFHPISSINNAKIVEKVSRFIRVKILSQIDGDYMLTGQSIFNFDFEKSKQSIINDIEKARFFLFEEDLFHQLIREAKLLVNYNVSIISNKIIIEINNIIIEIESIVYDELNEEELENYYQNVNEYSTLHNKKCQLILNYLKLMLCCYYKYNLKLKQKVPTALTKWKQSNSHPLILRPLVGNMRHELNLLNMKSVLDRLMHAHESELSYSKLDVEKFINLATRSKKQNPFQKSIEKPISKFHLVLCNKTSNMLDVNIQLTTNESFVNLIINMTIIRFETEDDFKNNVNGINVLQLGFSDFNEIEECLDWSIQNFV
The following text describes a protein:
Function:
May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Miscellaneous:
MISCELLANEOUS: Contains 2 motifs that are conserved in esterases, but it is unlikely that this protein belongs to the catalytically active pectin esterases.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MATTSHNKPSLFPLLSLLCFISIFLLLSLSKRASLSSPKTHRSATVFPPKPDGSLSPLSATCDFSEGSWIYDPNPRSTRYTSSCKEIFKGWNCIRNNKTNGFEISNWRWKPKHCDLPSFDPLKFLQSHRNTNIGFVGDSLNRNMFVSLFCMLKSVTGELKKWRPAGADRGFTFSQYNLTIAYHRTNLLARYGRWSANAKGGELESLGFKEGYRVDVDIPDSSWAKASSFHDILILNTGHWWWAPSKFDPVKSPMLFFEGGRPILPPIPPATGLDRVLNNMVNFVEKTKRPGGIIFFRTQSPRHFEGGDWDQGGTCQRLQPLLPGKVEEFFSVGNNGTNVEVRLVNQHLYNSLKSRSAFHVLDITRMSEYRADAHPAAAGGKNHDDCMHWCLPGLTDTWNDLFVATLHTIKAL
The following text describes a protein:
Function:
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
Subcellular Localization:
Nucleus.
Sequence:
MLMVVYVDSKTFLNRSSLKKDAQLIMTNTTWPTLERLTMDLNQSMEFTPSATSSPQIHNFMPMTSFMLPFHQPSNEDGEEVKQSHLLVQKRSLELFWYQQMLEIHNISAFKSHHQLPLARIKRIMKSDKDVKMISADTPILFSKACELFILELTLRAWLHTEEDKRGTLQRCDVSKAIRQEEALHFLFDVVPLINHKDDDGKFLEENEHHPVNQPQFPLLDMNAELVIRSPEAQQYMIKPPMSSHEFD
The following text describes a protein:
Function:
Putative antitoxin component of a toxin-antitoxin (TA) system; its cognate toxin is unknown.
Sequence:
MFMRTVNYSEARQNLAEVLESAVTGGPVTITRRGHKSAVIISAEEFERYQTARMDDEFAAIMAVHGNELRELADK
The following text describes a protein:
Function:
The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits (By similarity).
Sequence:
MKIIIFRVLTFFFVIFSVNVVAKEFTLDFSTAKTYVDSLNVIRSAIGTPLQTISSGGTSLLMIDSGTGDNLFAVDVRGIDPEEGRFNNLRLIVERNNLYVTGFVNRTNNVFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTSYLDLMSHSGTSLTQSVARAMLRFVTVTAEALRFRQIQRGFRTTLDDLSGRSYVMTAEDVDLTLNWGRLSSVLPDYHGQDSVRVGRISFGSINAILGSVALILNCHHHASRVARMASDEFPSMCPADGRVRGITHNKILWDSSTLGAILMRRTISS
The following text describes a protein:
Function:
This protein called 'barrier activity' is excreted by yeast cells mating type a. It is probably a protease that cleaves alpha-factor and thus acts as an antagonist of this mating pheromone and establishes optimal pheromone concentration for conjugation.
Miscellaneous:
MISCELLANEOUS: It is found only in a mating type cells; MISCELLANEOUS: Present with 672 molecules/cell in log phase SD medium.
Subcellular Localization:
Secreted.
Sequence:
MSAINHLCLKLILASFAIINTITALTNDGTGHLEFLLQHEEEMYYATTLDIGTPSQSLTVLFDTGSADFWVMDSSNPFCLPNSNTSSYSNATYNGEEVKPSIDCRSMSTYNEHRSSTYQYLENGRFYITYADGTFADGSWGTETVSINGIDIPNIQFGVAKYATTPVSGVLGIGFPRRESVKGYEGAPNEYYPNFPQILKSEKIIDVVAYSLFLNSPDSGTGSIVFGAIDESKFSGDLFTFPMVNEYPTIVDAPATLAMTIQGLGAQNKSSCEHETFTTTKYPVLLDSGTSLLNAPKVIADKMASFVNASYSEEEGIYILDCPVSVGDVEYNFDFGDLQISVPLSSLILSPETEGSYCGFAVQPTNDSMVLGDVFLSSAYVVFDLDNYKISLAQANWNASEVSKKLVNIQTDGSISGAKIATAEPWSTNEPFTVTSDIYSSTGCKSRPFLQSSTASSLIAETNVQSRNCSTKMPGTRSTTVLSKPTQNSAMHQSTGAVTQTSNETKLELSSTMANSGSVSLPTSNSIDKEFEHSKSQTTSDPSVAEHSTFNQTFVHETKYRPTHKTVITETVTKYSTVLINVCKPTY
The following text describes a protein:
Function:
Mediates the transfer of lipids between membranes at organelle contact sites.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MLDSFVAEALTSLLGQYIELNPDALKLSIAKGEVTLNNLSLRRDAFNRLNLPISITTGSLQFLHVKLLSLFDLKVQIDIDNVIALCLPQKEFTYNQKEAIEKELKRKLERIEEFESFTKLTNGKPGTKVRLIRKLLEGLIVSITNVHIKYKDNDDYIGVKINEITFANAKVQPNGIIRKEAVIGTASLYAGKGDLEFNDPIPKKNIITTISELTVIIDFIQKHYKQVRAYIKVPIFKGVLTQMQYQEFLSVVSRLSEYAQAMKFLGIRPQKRVIGNEKAWWKFAVEAIKNKRMNEENKGIREDVIKSVEEKYTEVYIKWRNDNKTKDLEEVKRMDDKLREEEVIYLRKKALKKAAASFTGGWKKKMMGMKKEEMEALCQMLDSNETKIDDKEEVLHIEAELEFGEVSLNNNDQSRTILCIIASKIDFKCIIYGKGFHVGITCDYASINEKVSAYPEVLKKSVKELPLVKCTIDRPITGPDAIINVRVAGTELCINKILLMNLYQFFMLPEQISLSQVKYFVEQQLTKFYQITTHRLDDFLTDHQTTVQLDVEVVAPTITVPLFFNDSESPFMKMKLGQIRIITIENPIGQKFAYILNNVSCASYPSFKNSSCTDDDANYIIQSISGNGEVLVGEPNRPFIDIITSFKPFVSKISKAKIDLIKEYINEYTDGWDELIVPKQCEQEESLDDVEFLKQQRGMVKALLKRVATESVHIKAVLERFEIGIAQIGDSSEKKMVTKLVVENVGFDLGIKANGFDCKAEIGSIELEDHVNRKPQIPFIFSSKIENCSQCYLANIHVGWGQELISVQGTIQIGRMRVVIQPKVISELIKYGMSLLFSYQLDNRSLEEKRKTIRKGLLTLKESKVIEDEINTKNDIIKKSESIKEKSSIQNPRNKILNELKRKIEIELKVIVEECGLCLIEDSNVVVCNMKVQGIETGVQWKGSPTIDLSIRQACIFEYDVVGNKEQPVLIYQGKELLVMKYNQTRMKVSTKNLIIHNVFMKLNMVQCFICPSFITRSLKIIGSDSIIKAIDLEQIHKQIVRGFISFSNNFKTIVKSISIKSRGGLNNVNLFNPKIELNSPHIRLFKDYSSGNYSVNASVGIIIINSLINVTEDKINQEIELKVDKCNVTTTQKSEVIPIISNLSINCNEKTNIEIGEDVKRNTKVECVVKQLLQVNIKAKQVKFLIDYFFEVKEKLDIKTLMKLFGHIKTTRARRAIKSEEYTQNLDRSTRKEKEYNFLIDVDVSCIQVMFGDINNVALASINGIKTNVKITKDLYLEGEIEVKDIIIEDARPVAEGRFHRLLGKLKEKPFLSTSIDMYLPTLQVFCQSNIESLSIVIIPSLIGDLALIGIDLTPQITKVHEKKHFVKKQKPVRINVLDIIETIVNNGTNKENKFKVDENISTTFNGNEIFLRLKKKLNISEHQTEYLCDELLRQSILIGKYPFDKYHNYKFSTSDITKDSVIFLSSFEEICPKEIVEESDLNRFIFSIIVSDISFIFVMDDENINTPYLLMQANGTGQVTIKKNNKSNFLFTINKAEWKSCQAKNGELTYQGVILNEGFDLSYHGDILFSEKLIEASTQCIFQPGKFIFSFDDLKMLLGCAKTLKKIFECVMKKLKDRPQTKKIITLATLLTNPPSFRIKGKNVYIKSTFGITNFDLILNHPLILSPLYKLTVVQAETKLYTYNDDIVINIAPLISFNFFNEKFGEYENVFNKIQADVIVRVAGDIVHGEPRLCLSVNTGFGNMFDISVTKELLDSFFDVYKELDQFNQTALGVGEYKPVRIINQMTTESSKLYANTTGTSNIELLSNTIVELPLEAKRKQIKEFTLRIRNEDIKIPLTTTITQLHVLQNKVYFFSKMTYDIDGSQLVYLITCKTIKNSLDIPIEIRLNKGNLSKVMSLKKGEAKPIPQEFIKESITLVIQNQSVVINSDELRETTLIPLDTKKTMFIQSEKITTDYEYKDAEIYDFLIDIRYAFSITNLLPRIICIGNKEETHNIDSCQTKKLFKNLGKRIQFDGEGSTIWINTRDISYSDIDYYQLKNGTTIRARWNKGDCVIDSEFLVYNKTDENIFACVGSNKILLQPLGNGEILTLNKCNLKLIMCEGISESLQSESITSGDLCINGKKKTNYIHLELSSNPQFQGIKIITITYAYHIINTTQHPLFIQCPNQTNTINELQPNQIKIIPLVLPPTKSSDIVPSFKLACNKEGPYSELFTCVSGSSCGVSLIQSSDFNNRVNLFISVRNYGVGQCVVIENETTLKCKNKIVNDTDVPIQYLWSVTNNLGLSTSVDPHTETTINIHNIIDIDHIVICAPFLKNQYVSYSLKKLKFYEPIISGTTLFFAYTFIIDGITTLTFTCDQLKVMRECPLFILSNNPDLSTTGVFEVPIINFSFKAPIIGIDIIDQRRVELCYGKLINLTANVRINAKYSEVVCDVESVQIDCDEVNTQEEVFLSIQKTSLPAIHFSTQVIQSETSQNFFYFPFINVLVQPVTVALESKFIADLYQFFKSLHFKIKEIQKEVTQGIPPMNSSIYTFIRSLVLQPIVLYFSCSLQPSHLVLIPYNAFTAVLHALGSSLLNIRDSIIKLNATVAKNVNGDLSSLKQIFVEHYYKQIINQAILLVAYSSFLGNPRGLLNDISTGCHDFFYEPAQGLTISVSSFGKGMINGVSSLAQNATHGAASSISGITGSVSTFVASFSFDKAYIEKRNSDKRAKSTGDGIRKGFVAFSSGVFQGITGVVYQPIKGAIDGGITGFISGVGKGFVGLVTKPIVGTIDLVTKTADGVRASTGKMQIERIRDIRTINPKYSLKPYDRNEAFLSRKMREDNLGNIITSYISNGPVTWVLAEKRFIVYSQGKLNPYHYSLITITKTPDGLFMKCSQFNKESKLIISTTSVQCKIFLEFASDLVTLK
The following text describes a protein:
Function:
Probable regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSVTPVILEAYCAVSDEVAKQVKKYLLGDFAEESKFERKNSESSDGSETQFCRATEKKENVEVWDDWGDKEEGAAENSLESDESIRNWLFRCDLKTYSDAEYLLVTWESRFVVLRKPPDEPVYKIVCKQYIEGDPISNEITASSIFGLSNVRHIELLDSIIIALGTLDGHVYFFTEQGTMLYFDRFSIFEPVNSLQFEVVKTGQTFIVVFTKGFFMINPISLKSVLYQAKVLIAKCEKTVKQISESIELQSELLAPDIKGNIIHVIFTGLHKPSTLEQYISASYDSFYAKVEKPSLPLYSTFMVTTEKEFAVFVWHDREEQDKLIDDVIKYGKSLVPSFGIRKFFGISTEPARIASHMRSAVHAPTRSIIMETRVAQNVSRSPDCQYVAVTDRMARVLVIDIASRQVVLIFKGYRDASISWVSVTEDDRVAQFLTIFAPRRSLLEVWTVLGNVRVCAQHVPSSECNVVTGGENKMLCGRCHVHTDSNSFFIDEKGEFHRIALPFHLALTSRSRQDQHDHLLLKQLENTKTGGEDWFQTFSDLKMATSRKTTFQNALHNLSTAEEAHQFIARIRSIPTSASLGDLPNSAEKSIGFYARTVAETKPPVGEYDDKDTSNYKLDSIVERILECHMQKFGERTDMLNDSEVMKVGEWLKYVDLSQEDIDVFSEHWSEKQRHCLANLIFGPLFGSFEIDEYYDTVLEKIPVKRKNIVKLFYMRFEKTTTHIDWRIFNRIVEMFLNLEKSETGILEQVDQMAMDSKDVPLGMILLSICWCARIQIRILKGNDEDEVENDHDLEEEDEKNKTIDEWDAISPEAEHLDCIIMCLHCVSLAQSLLKDDSNILRISDVVPRIDSYIRENVAKWIVSTPIDTDTIEKLFPRDPSENLAEKGNEEDRRKQMIIDFPDDKEVVIQRMYQIIPRVFEHDLVVADVCWEMMSQWFREKDDNFSYIKDCTTLLPQSIVDPRLRHGIARLIWDKFIFMVFQSIVNMVEKTGRRPKDKETRKEIGFGEVKLEEFLMECEKFLEVLMDSVRDMPPPIDFKQDLLVEMASSSFAAHLHQSKTAYRQDQFAILASRQPLVNFHLVLHHQHLALALRLQLTTGLRFHPLRNLFCVTGNRAFFASLDSHPLIPLDRVDDATMEKRHAFLVKVAEQGSMEERRLARHLEMEWKLTVNEISFMQALSSFRLGNDHQGSLELASCVRDDRSAVALARVLAARLIQLANEANKRYSTAHSQYLCALAGEEAARVELYENSPDDPLVDSNPKTWKDAVTSLGRAGNSVPQSAQAAIPFVRMNDIAKLYFGAQWVNN
The following text describes a protein:
Function:
Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development. Together with other vitellogenins, may play a role in modulating life-span, acting via induction of autophagy and lysosomal lipolysis.
Subcellular Localization:
Secreted.
Sequence:
MKSIIIASLVALAIAASPALDRPFSPKSEYVYQFDGLLLSGLPTTFADASQTRISCRVRLQAVDDRYIHLQLTNIEYSASHVPQNEQWPKMNSLEQRELSDELKELLELPFRAQLRNGLISEIQFSTEDAEWSMNSKKVIINLLSLRTSAPIDEMIQGEKYMETEKDSRFFTVNEKTMEGDCEVAYTIVEEGEKTIYTKSVNFDKCITRPEMAYGLHFGSECQQCEKEGQFVKPQTVYTYTFKNQQLEQSEVHSVYTLNVNGQEVVKSETRSKIVFVEENKINKDIKKATGPKTDIVFSAQDEILMERFCQQGDKAEVNPFEVMPSQQKIEQLEKIFRQMQELEENTPETVHLIARAVRLFRMCTIEELKKFHTKVYTESETKKLSLQVQLLVQSSLAIAGTRNTIQHLIHHFHKMTVSPIRAAELLKSIQETISPSEEIADLVIELAKSPLAEKNEPLRQSAWLAAGSIVRGFSTKTQDLPLTRPASRQLKEKYVRVFMQLFRSAESTYEKVLALKTLGNAGIDLSVNELVQLIQDPRQPLAIRTEAVDALRLLKDIMPRKIQKILLPVYKNRQNKPELRMTALFRMMHTLPEEPILAHIVAQMEKESNQHVAAFTYNVIRQFARSTNPCYQPLAVRCSKVLLFTRYQPQEQLLSTYSQLPIFHSEMLSGVQFDFATIFEKNAFLPKEVQASFESVFGGNWNKYLVQVGFSQQNFEQVIVKALERLSRYGKQSNELRSRRVQSGIQMLQEIVKKMNIRPRVQRTDAQSAHAVFYLRYKEMDYIVLPLDMETLDNLLEKYVRNGEFDIKSVLSFLNADSKFELHRAIYFYESIRRIPTTSGVSLTISGKMPTVLSFTGKVAVEMQKLGTRLILDVVPSVATSHVTEMLKSLQSARVHTTFRLESTVELKKNTLEITHKFAVPENKKTIVSVHSRPVASLRVPRNDQYVEAEEKTISHSEYQWTTEEIDRKYEVLGLRVNAQGNILSQWSLPKVLMTEQDFEYTLENKNRPAEFTARMTIGNLEKTDLSEIKFDKIFEKEFDSENTESESRRQYFHKMIREIKAEQGYMNLITLKLEAPQQTYFNSELRTTCDQWVRMCRFEMDSRRSPISEETKEWTLRTELVAARPQMPSSLRQLREQPHREVQLALNAKWGSSKKSEMTVTAQLEQSKEQKKYIRNIERVFNGLPEYELLIKAARLNQINVVSEYKLTPEAEHTFSRLFDLVKAYNFWTVSEKRVENEERRVTLQLTVEPMSRQYVNMTIQTPQQEVEIKNIRVPRVVLPTIARRAMIQQAWEKTETTCKVDQSEVSTFDDVIYRAPLTTCFSLIAKDCSEEPTFAVLAKRMNKNSDELLVKVIRREQEVIVKKTSEEFLVKVDGKNIPQSELEQYEIEILGDNLVVIRLPQGEVRFDGYTIKTNLPSVASKSQLCGLCGNSDGEKDNEFMTADNYETEDVEEFHRSINCIFALNNSKIICRSAKLKTTVFPRRRTTETNGTERRRRETNLLPRATRNTRRNPRSPRRVSKPVEIGCKSXXXXFLLSESVEQTQIKEFSHRVCFSLEPVAECRRGYKTDETLTKKIRFTCMPRHSNNARRFLKEAREQTVLDLSDFEVSYVEAVKIPTACVAF
The following text describes a protein:
Function:
Magnesium transporter that may mediate the influx of magnesium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MARLQRQLLRSVYSFLNLSSAECLGVACRGFATQTPKSFTFSTGLVSKERNCKVLAGLDLFKVYFNGKYSASGIRVFSAESGEGGDGEEKVHHLTKIDGGKKYSVVQIDTDGSWKTVWRNAMELGIHPRDVSILAASNPFISQRSTIAVQNEKIMVRMENVRALLCRDHVLLFEARRPRSLKDRDIVGAAPSVSETPEKAAERARELFAVYISQQAREPIERLVEAMPFHLRMLECLLDDTSIFFHQKTERLKVVVERMLEELTDDVNMGGLQRLLPLKRALTEVEHDVRDTHDAIEEVLRSDEMLEAVCLNKTEFQWSFGKYSDSERTRDSKQPTLRQAAADMLLTYQRQIDNAGGALEELRKNIDATQEIWELGLDTTRNRIIQIDVLFSLGTVSMGVAALVAGYFGMNIPNKLENSPTAFWWVVVGSMGTTFLLGAFLLYLVRIRPRVMDRRRARELAALRDLLKHLDDIDDIFQAVAREAVAGRAVTPNEFKRILHSHPTARFMRKGELDMMFRMFDTDRDGVLKDAEMEGKKTTN
The following text describes a protein:
Function:
Catalytic subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MVTVNLKSLLIFSAFLRVFLIVYGEWQDRHMEVRYTDVDYLVFSDAAALVAAGKSPYQRSTYRYSPLIAFLLVPNSFIHPSWGKFIFSASDLLVGFLINAILKLRGVPEKLCTYSVMVWLLNPFTFTIGTRGNCEPIICAIILWIIICLMKGRLVQAAFWYGLVVHMRIYPIIYALPIILVLDPLFFQYGTKPALVNWSSRKSKSHQTSSCKKLMDPYCIWNFLTSLFTWRRIMFGFISGAMFFLLTGVFFYLYGWEFLHEALLYHLTRTDPRHNFSIYFYHIYLHYEHEFSSLEKLVSFLPQIMVQLVLVFRFAQDFPFCFFVQTVAFVAFNKVMTAQYFVWFFCLLPLILPWTNMKLKGKGLVCILLWMAAQGHWLMWGYLLEFKGKNVFLQLWVAGLLFLAANTFVLINIIQQHTYSPVFQQSSPAASKKHVKQG
The following text describes a protein:
Function:
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate.
Subcellular Localization:
Membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MERLNELCDIIEQNPKQFLDKLPWICQQCPQSKLLRAESPRFSQSHLNAILAVTRILSKIVDTTDENAKFVVLDFLQTVPKSFHRSFWPYSLSLESISAFYCSFLGYVSCLSQLMVEGYLLRAAQRSDIFAHTLIWHLQGESVEEIVKDGAFDKNASFQEILSDVRQHIVDGFTPKALNFFSREFDFFEKVTSISGALLPLPKEERVAGIRRELEKIKMQGEDLYLPTAPNKLVRVIQVDSGIPLQSAAKVPIMITFNVVDLDGDHNDVKPQACIFKVGDDCRQDVLALQVISLLGDIFQAVGLNLYLFPYGVLPTVVPNTRSRSQMGETTDGGLYEIFQQNYGLVGSTTFETARANFLISSAGYAVASLLLQPKDRHNGNLLFDDVGRLVHIDFGFILETSPGGNMRFENAHFKLSHEMTQLLDPSGVMKSKTWHQFVSLCVKGYLAARRYMDEIISTVQMMLESGLPCFSRGDPIGNLRKRFHPEMSEREAALFMINVCTDAYNKWTTAGYDLIQYLQQGVEK
The following text describes a protein:
Function:
Transcription factor involved in yeast cell adherence to silicone substrate, filamentous growth, and biofilm formation.
Subcellular Localization:
Nucleus.
Sequence:
MSAPIVETKKASKRRIRRIPDDQRQKVSSACDNCKKRKFKCSGEKPCFECSKKGHDCTYTIIDKRSLRGERMAKLKQKKDNNEKQRELVNEQIAQSSIIHPQITPVLPVPEYANVTYQDSSHSTVSGNDSYHLSSSSSIPQNLPAIVLPDTLRDPNNRGILTPGSTPNSVSSESSVSNVCVPKSLQPLLSFPLENKNNLRHKSEEPDMDNNTNNVPKKGGISNQEGKSAILLVDKSGAFRYMGETSPLSVLYEARGIFYEYVGSTKLTEDLRGCPVTDKPLKITMKEAAPLPHPSERDVYIERFKVNINGAYFVFDMDKFYEEIVDKVYENPNSDLVQENRVLLYFVLAIGSTYKDFSERNPQAEKGAHYFESGRLILRDLVEDSAMWCVLCHYLQFHYYESILKKSTALVHLTAAINYAQSLGLHRNFVNEQFSKLTAEYEYRRKLFRSLYISDRISSVFIGRPLIINDYDWDDPARFKNTNASVLPLDFNSKCHIELTRICTLVGRIVANFYQDKMIDVKKTKNLAIQLRLWSKGLDPELAFGNVLNPSQISNNEDNGNTVILLGIHILHLWAVMLLSRPFFMFEAISKINPEMRKSFEEEEELSKQLCQAATKASILAIKLMNHYINTTFHEIKRMECYVIITCCFYASIILGITILNGTFEEAGYTENDLMNSLKDAQYILSQFSVCNKGAERYSEINLDLISALVNRHKGKEVKPVVDNWSCNLFNDFNFGDTSGQNDVQTMMDFQQFFVSSDLIQFEEITDGTSSLPFDYNNYNLFFGDKL
The following text describes a protein:
Function:
Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MAEIQTAQNPLKELEKILERNNKQKNKKSRNQVRREKKKLLREKTNSGAKLAEKNSDDKDQLTENNDNLYNDKKSNGNFYDTNKTDSVDGMVYTTIVDSVELDPNDPLIEQFKDVFNRFKADGQEKDFEDTDKGQIMYSDDEILSEGEEDALQKQQEEKLSKKKLRKLKRMTVAQLKMLSEKADVVEWWDVSSLDPLFLTHLKAYPNTVPVPRHWNQKRDYLSGQRGIERQLFELPSYIRATGIVQMRNAVHENEADMPLRQKMRERVQPKMGKLDIDYQKLHDAFFRYQTKPVLTGFGECYFEGKELEADVKEKRPGDISEELREALGIAPGAPPPWLFAMQRYGPPPSYPDLKIPGVNCPIPTGAQWGFHPGGWGKPPVDQFNRPLYGDVFGNVKPRIHAGTGSPVSTQHWGELEEFEEEESSEEEESEDVEYPTEEITERETIEEYQSASEPRSQREDLHAEPLTYFNQSNVEVDNVELRKNTQPSSDAANRDLYQVLPEKSTNISGFMGPQHQYDIPTAEDTLPQKRNAHSMLSSTNKGDVALNQSSNWQDELSELVSEQAMKVGAAKRQKTQSKRDKFRL
The following text describes a protein:
Function:
Minus-end microtubule-dependent motor protein. Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase. Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis. May also act as a negative regulator of amino acid starvation-induced autophagy.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MEVIPPAVCGEEEAVGAIPPAVCGEEAVGAIPPAVCGEEEAVGAVPPTVCGEEEAVGAIPSAVCGEEEAVGAIPPTVCGEEAVGPFPLQCAGRRQWGHSLCSVRGGGGSGARSPRSVRGGGGSGAIPSAVCGQEAVGPFPLQCAGRRRQWGHSLCSVRGGGSGAHSLCSVRGGGGSGARSPRSVREEEAVGPVPSAVCGEEEAGSCLPLLFQVQVLLPGLSAAPLGSAGPGAPQDTGEPGGAVVQRGLGFRRHETFLNAWTPAPSPGSSCFFPLPLAPASSHPLSLPNACTCAGYWGGERPEAEAMPAGGGRWGSFWEQRTRQLQSQVRAKEDKIAELETENAVLLLKLAEYKGKIEKSRSEATRISTLYNKQQRLQRNTRSALSQLDRVIQKLNQDIQAFHSSSRALLRDYQDEYQDRVSAIVTAVQRTRQSAETLLVCQAKVVHLEQALQDVSARHQLERQRRKALHNSLVELRGNIRVHCRIRPLLPFDSESDDPVLQSSSISREVAHAVDDETVLVKCDRPGHPLINKTYHFERVYGPAESQSAVFGDVCPLLTSLLDGYNVCVMAYGQTGSGKSYTMLGPHSDDGPVLPLDPQSDLGIIPRAAEELFRLISENPSRSPKVEVSIVEVYNNDIFDLLAKDTVAAVSGVKREVMTAKDGRTEVALLASEAVGSASKLMELVRGGLQLRAKHPTLVHADSSRSHLIITVTLTTAACSDSTADQACSATLPREQTEAGRAGRSRRTSQGASAPQPVPGDPAGRAEQVQARLQLVDLAGSECIGVSGVTGSALRETACINRSLAALADVLGALSEHRSHIPYRNSRLTHLLQDCLGGDAKLLVILCISPSQRHLAQTLQGLGFGIRARQVQRGPARKRPPSSQMEGKRRPD