lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Scytalone dehydratase-like protein; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxygenase mdpH that catalyzes the oxidation of emodinanthrone to emodin (By similarity). Emodin is further modified to yield monodictyphenone via several steps involving mdpB, mdpC mdpJ, mdpK and mdpL. These enzymes with xptA, xptB and xptC are also proposed to be involved in the synthesis of shamixanthone from emodin. Especially, direct reduction of emodin by the short chain dehydrogenase mdpC followed by dehydration catalyzed by the scytalone dehydratase-like protein mdpB gives loss of oxygen and formation of chrysophanol intermediate in two simple steps.
Sequence:
MTLQPTFEGRTPEQCLNVHTDSHPDITGCQAALFEWAESYDSKDWDRLKQCIAPFLRIDYRAFLDKLWEKMPAEEFVAMVSHPHFLGNPLLKTQHFVGTMKWEKVDDSKIVGYHQMRVAHQKHLDSQMKEVVAKGHGHGSATVTYRKINGEWKFAGIEPNIRWTEFGGEGIFGPPEKEENGVAADDQVMNSNGSSEVEERNGHVVNKAVEVRSV
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MGMIISPTRELSAQIYHVAQPFISTLPDVKSMLLVGGVEVKADVKKIEEEGANLLIGTPGRLYDIMERMDVLDFRNLVILVLDEADRLLDMGFQKQISYIISRLPKLRRTGLFSATQTEAVEELSKAGLRNPVRIEVRAESKSHHASASSQQLASSKTPLGLHLEYLECESDKKPSQLVDLLIKNKSKKIIMYVQHGNFSEDG
The following text describes a protein:
Function:
Zinc ion transporter mediating zinc entry from the cytosol into the lumen of organelles along the secretory pathway. By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle. Golgi apparatus, trans-Golgi network. Sarcoplasmic reticulum. Mitochondrion.
Sequence:
MLPLSIKDDEYKPPKFNLVRKVSGWIRSIFSDTTSRNLFCFLCLNLSFAFVELFYGIWSNSLGLISDSFHMFFDCTALLAGLAASVISRWKTNEAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGIERALDTPEVHHERLLPVSILGFLVNLIGIFVFQHGGGHGHSHESGHGHSHSLFNGSLSHGHSHSHGGSHGHSHGGGHGHSHSHGEGHGHSHDQSHKHGHGYGSSCHDEPPEEHTGSSKQILEGVFLHIVADALGSVGVIISTILMQRYGLMIADPICSMLIALLIFVSVIPLLKQSIGILMQRTPPSLDHVLPQCYQRVQQLQGVYHLQEPHFWTLCTDVYIGTLKLVIGPEADARWILSQTHNIFTQAGVRQLYVQIDMAAM
The following text describes a protein:
Function:
Critical for epithelial morphogenesis during oogenesis; border cell migration. Required in the germarium for the polarization of follicle cells during encapsulation of germline cells. Required for embryonic segmentation and trachea specification. Essential receptor molecule for upd and JAK/STAT signaling during oogenesis.
Subcellular Localization:
Apicolateral cell membrane; Single-pass type I membrane protein. Note=Apicolateral membranes in follical cells.
Sequence:
MVAQEQLVLLLMLLAGCRGGANAILDPGWVIPSKVEQLIGGDFNLSCTLNEDYFNGKSAEDCPVEKLYFTGGGRVYRDSKHIRILNNTTILFSDTNAVEQENDYHCMCDEYVINKSKVYVGTRPLLVRDFNCLDYDFQFMVCNFTQPPNTVITKYNISYNTNNDWRYSNTLDCNFDSAPVVTCNLTDDNYKRFSETFYFRLSISNALGHETQPITINHFERLVPARPGQNLTLLNRTESSVCLSWEMPRRSNYNRGLVWQVRVTPQNFEPITRPSWRNHTLTIKDTLCLTELPFAGYNYTLRVRVRANQNNTLWSEPMIYAFATAPAPPRRPPRVTYGSFYVYSSEKAMRFYWEPLEEHELNGPDFRYSISEYRINGTAVDPGLIKVESNSAMIDHWSMSAVHHFLIRSSNSQGLSVNATPMTIGPISNRDFKVREPRNIRSVYHPTNKSYTLSWDPPSDQRELQNYTVFWCVPKPGLQSECEGSIRFAEVASGLHHFTTSPDQLLTLHMAVSANYQSHNTGLHWAICSSDKKDDLAKMEPSIDVATSTSLTVSWSERVCAVILAGYNLTYCQRSAGRPDNCTTVTIDRYTNKHVIQNLVPYTDYSVKMLMYSDSRVSKYSDELVNRTGEAAPSQPRELQLIRVTSDSVELAWKPPLLANGVVRAYEGTFRSLHDNVTDTFRVSASADELVNNEKPITYRLGNLTAFTKYEISVRARTVYPSEPSNVILFSTAIGVPSPPQLYVINNPDQSSRLDWEPPRTPAGRIDFYEISLRDNNASCLTSTILPGRNLSYVMATPRCTSHNPFQLAVRAINVEQHPQLNGADAAEGAVLLMSTNGKGCEARTDALGEEERLQFEAYAANMTAYRLYRSDWGIYGFICTPDTHSVKAMYQTIEVTVAILVLGVIFYLVYKKYRKMSDIGLVLPQGIMETMKKPIDMGGLGLGLGPDSSVSGGIVCTRVDDSPPYTPQDLPHDFSSCGSESSKLLLRTASSSGGGGCVDRDGYDDNHETGPISAVGPPTSYLAMRHGLLVQNDRERERERDREQEREREQQQQQRESEMDREQSCTNGYIKPTQMKSWGGNGPSDNDHTFSVPSTAMTAPMSQPLSQIPLSGYVPVPIPQSRFNPAPVQPFGSPAVPSAATAAAASTFFPPAHLLNMDNYVQASDLHKLKPLVAAPLSQTGGPAFAGSSPATSPPLQLPPVHAASPAAATPKMADIGYTTMEQLQLTGLIKPPLAATVGSPTHAAGGAPGGGNQHSRLQPQINGYVTPQDLNAMAHNRHVL
The following text describes a protein:
Function:
Regulates the transcription of a set of genes, many of which encode membrane proteins. Among the genes regulated are YGR138C and YRO2. Does not seem to be dependent on copper.
Miscellaneous:
MISCELLANEOUS: Present with 339 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MVLINGIKYACERCIRGHRVTTCNHTDQPLMMIKPKGRPSTTCDYCKQLRKNKNANPEGVCTCGRLEKKKLAQKAKEEARAKAKEKQRKQCTCGTDEVCKYHAQKRHLRKSPSSSQKKGRSISRSQPMFERVLSSTSLDSNMLSGHGALSDTSSILTSTFLDSEPGVGKISKDYHHVPSLASISSLQSSQSLDQNFSIPQSPPLSSMSFNFLTGNINETNQNHSNHQHSKSGNNWQDSSVSLPAKADSRLNMMDKNNSVGLDLLGHSKRISPISNSRVGEVSVPLEEYIPSDIDGVGRVTDKSSLVYDWPFDESIERNFSTTATAATGESKFDINDNCNRINSKSYSKTNSMNGNGMNNSNNNNINSNGNDKNNNNSSRQEHQGNGLFDMFTDSSSISTLSRANLLLQEKIGSQENSVKQENYSKNPQLRHQLTSRSRSFIHHPANEYLKNTFGNSHSNDIGKGVEVLSLTPSFMDIPEKERETERSPSSNYITDRPFTRKPRSSSIDVNHRYPPMAPTTVATSPGALNNAVASNLDDQLSLTSLNSQPSSIANMMMDPSNLAEQSSIHSVPQSINSPRMPKTGSRQDKNIHTKKEERNPLNNIHDLSQLENVPDEMNQMFSPPLKSMNRPDAIRENSSSSNFIIQGNSMISTPSGRNDLPDTSPMSSIQTASPPSQLLTDQGFADLDNFMSSL
The following text describes a protein:
Function:
Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex (By similarity). May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Presynaptic active zone. Cell projection, podosome. Note=Recruited on Golgi membranes by RAB6A in a GTP-dependent manner. Localized to the cortex of myotube podosomes (By similarity).
Sequence:
MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGNSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGAETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQQLEREIARYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFRSSRSNQTNHKPSPDQDEEEGIWA
The following text describes a protein:
Function:
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against viruses via an alternative antiviral pathway independent of RNase L (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MEQELRSIPASKLDQFIEVHLPDISFRDELREVIDVLCILLKNRCCRESSHPVRTSKVGKGGSSRKGTTLKGWSDADLVVFLDSFTCFGDQLNRRGEFTKEIKKLLFEVQRDRHIGVKIEVHSSWSPNHRALSFKLSAPDQQKEVKFDVLPAYDLLGHVCIPRKPNPQFYANLISERTSLGKEDEFSTCFTELQLYFLNWRPTKLKSLIRLVKHWYQLCKEKLGDPLPPQYALELLTIYAWERGGRLTKFNTAQGFRTVLELITKYKQLLIYWTVCYDFQHPEVSKYLRRQLKKPRPVILDPANPTGNIAGSNPKGWRRLAGEAAAWLRYPCFKYKDGFPVCPWDVPTEVDIPSQNYFFHIICLIFWLLLRLIFGKHSV
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MNPGETTPPSPLDKPLAELTEEDIAQLTREDCRRFLKAKGMRRPSWNKSQAIQQVISLKALLEGRPGCDDCPAGGGILQKLLTSSPSEPLSPPQDSPPPAPKEGGSGSQPLAKEPSPYRRRDPIPPPYSAGNPTCQTPIAGADLPHPPEKRCPSPRLTAEVPVGQMTIFYDGMVNVYDGVSADQARSIMELAASPVCFDDPTGAFSPARPPAFRFPPGLPRPAPVPTAPSFVGTFPISPAGTMIHRVADGSDDRRVPRETEPEGPTSRKASLQRYLEKRKDRFKGKKIIGGPTSSNMEMICFNQKLSCPNQNELPNPCDTSFPTLIQQPQSPAKCSPAENETQREKIFFDLNDDG
The following text describes a protein:
Function:
Controls the nucleo-mitochondrial dependence of galactose, maltose and raffinose utilization. Becomes essential in the absence of functioning mitochondria.
Miscellaneous:
MISCELLANEOUS: Present with 5110 molecules/cell in log phase SD medium.
Sequence:
MQKSILLTKPDGTQSNLHSIKTETPTTVEFDSEQMERGHRERGRSKKKRGERDSNVSSLSRSRSRASSRSRVREEEFLKWTVLRQDPSMRLRVVDVDSEEEGEGNDEDDDDGDGDDMDEEESDEEQVSDIENDLEIDEEFHYDLGMKVLPNFCTSINEVLDSSKPWIAKYEISIRGHENEDVSLEQLDGGYVRAMQLLTKGAGAEAGNQRSFILYTDLSSESTYALTYLMGAAVNQGDTVYIVHWEPSKPTDDSQMFANVARIRKHVMHLFDCVAGVLDDLDVVVLSLTHPYPKHLLNEMIHGLKPVALCCSLSVILSTLQNFVCSVPILAVRKKLKRAKRKGISE
The following text describes a protein:
Function:
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MMDNDNQFWKRFLIFTILMFLFITAYELFYIYYVKPSQPQKTEKKEVVKKEEFKNVNLPQLMLGTFREKQEYKNTKTVKLGIYSLELSEKGGKILRFIDQKYGFDLISKAERELKIFPLEIFTGNPDLDQKLNFGEYEIKEGKNSVELIHKELKVKKILSYKNGAIHLSVEGLKPPFWVFVGSPPDDEAFYTHVGPVLKINGEVVRLDVDDLKGINEFEGNIEFGGEESRYFFKGAKDYQKHIVYKVKLGDKFVSLSTFLYDGEKTIYLGAKDYARLRELGLVDTLDWGTLKIIVKPLFLFLYWIYEHTGSWVLSILVLTFIVRIFLFPLGYKSVVSMQKLQELAPKMEKIKQKYKDDPVKMQEEMMKLYAETGFNPMAGCLPILLQIPIFFALYKVLIITVDLKVSSFLWIPSLADKDPYYILPVIMGLTMILQQKMTPSPDPKQALVGYITSVAFTLLFINFPAGLVLYWTLNNVFNIIQNYLIKEVLLKDKSKGGSKKK
The following text describes a protein:
Function:
Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
Sequence:
MVEKGAQYSYCTRWSVIVSHCDIRIGYQPNRLITLAKVERRRNPNLHLSARKEGSPELQPQGAAQGNTSRVAPFPISNHGWVPPSTRGRRVEQPVLDVNLIRRRIQGILNKLTPDNFDRLANQLVHVGIKNKEILSIVIKLIYDKATSETKYCSLYARLCGRLSEDAPKFDEKSDSNSFRKLLLHICENEFHSRTKASSAFDSMAGDLTAEEEEARTLAKRRVLGNIKFIGELGKLKILDNKILYDCIKMLVVKGKPDLVELSEQLECLCELMKTCGRQIDTDKASDWMDDCFKYMEKKMKNKKLPPRTRFMLQNIIEVRQNKWVPRKCMTENGPKSISEIRQEAGMRPSRILQKGLHDGRESRPQPDIFSQRRTDFDPYFHMHEIYFRRDPGHGNHDISNMMQNPRFHPSVVAENFYMDPSYPGGFPPFNNPMANHNHNAFMNAQKQNQLHRPPQPQITLVSADDIRPSKPLQKEFRLENDANISLRPSDNSMLVSLASSQKNQRKTATQPNKVGPLISLSKLNLTPEKPRSKKSGKSAVLSREDYRNKVMQLIQLRKFYTACDIRYIDLLISCILEYGRDKDVAERKRLMQLVVHLSNEGLISKEDFFKAIKQYLQNIQKNDDEANTVKDSAADYIGELMFLKWLGTSESLKQIAEITHVSFVIAIFKWLERRVNKDYVVEIYEDSKIDLLLLIPDPDNRTMDHLMELLQEKDLGYLYPLQKVEMELLQKIREDPNSTVVFRWIKQTVDPSLYTSDDFVLGLSTCILKYVTENSTLPKNYDKSVQPEKPLVEKEKELMQGLKGLLHQFVHDKINLQMIVIYALQVFCYSRTFPKDLMQRMFNILYEEELCEEEAFLKWKEDLNDKYPGKGEALFKVNQWLTWLETAESEDSASDSD
The following text describes a protein:
Function:
Non-catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. The TSC-TBC complex acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. In absence of nutrients, the TSC-TBC complex inhibits mTORC1, thereby preventing phosphorylation of ribosomal protein S6 kinase (RPS6KB1 and RPS6KB2) and EIF4EBP1 (4E-BP1) by the mTORC1 signaling. The TSC-TBC complex is inactivated in response to nutrients, relieving inhibition of mTORC1.
Subcellular Localization:
Cytoplasm, cytosol. Lysosome membrane.
Sequence:
MKGDDSVHGDATTDLQSPREDVVTMASDGDHMIRKSLKDSNSDAPIFGELLDAEVTVNPMKLREASRAGIPPLYRSAVYRYLLGVSFVDKSREMTVERMQEKDFEQLEATFAQIVACDEKGGSTRCHASHALFAANCDTMMTRRESKFVNGYRCSDRFSTFGCTTWLAVLARLKYMPQFVGNHERRQRIESAWRALYVCHSEATPDEVNYIFELAIAFEAVYSTARDIYFSVESIYHLLTHHNNVLQNKQCLQHHCGVFLMLFRATNFELYRHFVTEGVSVLDWVPGILTTLLAGRLHVEDLLRLWDVYFADAQNCLGFPLHPYVCLAILAEMTEVLIECEKSGIIELLQNMPRMRMGCIIQRAIALKESVLSQGLL
The following text describes a protein:
Function:
Involved in the uptake of shikimate, an intermediate in the aromatic amino acid biosynthetic pathway.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MDSTLISTRPDEGTLSLSRARRAALGSFAGAVVDWYDFLLYGITAALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLGGVIFGHFGDRLGRKRMLMLTVWMMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPKNKKAFYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNGMEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIALRLCELLTMYIVTAFALNYSTQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYITGTLIGTLSAFPFFMALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVGGGFTPFIAAALITYFAGNWHSVAIYLLAGCLISAMTALLMKDSQRA
The following text describes a protein:
Function:
Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells. Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'. Directly represses transcription of classical E2F transcription factors such as e2f1. Acts as a regulator of S-phase by recognizing and binding the E2-related site 5'-TTCCCGCC-3' and mediating repression of G1/S-regulated genes. Acts as a promoter of sprouting angiogenesis, possibly by acting as a transcription activator.
Subcellular Localization:
Nucleus.
Sequence:
MEEGSKENCGFNGSPMGSRSPPKQLTSAASVLGEIQIAAANLKTPTKPQERNNADPWTPTANLKMLISAASPEIRNREREILEEQFSGDELEKTLPSRKEKSLGLLCHKFLARYPSYPNPAVNNSICLDEVAGELSVERRRIYDIVNVLESLHMVSRLAKNKYIWHGRLNLSKTFDALKKVGEENRYGEQIQLLRKREQEECDSQNSPNAETQKPLAKQPEVGFVELPGLEFRAASVNSRKEKSLRVMSQRFVMLFLVSDPQIVSLEVAAKILIGEDQLEDLDKSKFKTKIRRLYDIANVLTSLNLIKKVHVTEEKGRKPAFQWTCPELCTDDQENRSSPAALTPVAIDLSSPKENCAKNLFASGGKTFTRHPSLIKLAKSIENDRRKINSAPSSPIKSGDGSSSAASKMAQLAAICKQQLQQSRDQTKVKLKVSACKAKSTVKQPGGSDKNQTPTYCRAIPLLHPHPSAAPPYTVIVQPPQEQTLSRQSPPALAHSVPLAQGYTNRTPPEAPLQGGRHEGDGTSHSEDHSAQERHPKRLPESDRGCTSKRMKSSAVDDVTETLYPSGYLIPIHLAPVAPEPSKENTGPSSENKLFTSPIPGVFPLKLMFSPGPVTAVPVMSRGGQHVGGGSGSASRSPSPGMFTFALQNRELISAGLPQGATVSPRNGRGQEELSAASVLNCKHVSPVPYHGQPFTVFALQQSAVPVTPKGYHSLQETFFRTPGGMGCSPPESARKLDVGTDD
The following text describes a protein:
Function:
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDDYKNYFCTLSSALSFFRAIRDRRETPGSSVRWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW
The following text describes a protein:
Function:
Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules. Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore.
Sequence:
MSFTTKDKSDDSSIITTNYADNPNLSPIEQKILQQYQLMNNNLIKVSNELELLTNTTDEFGKGKGSSIHLVENLRQLETKLVFVYTFFKGAVYSILNAQDYIAEQETNGLEETNEEEDGNEEDESGNVELSGVSADEN
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. A labile antitoxin that counteracts the effect of cognate toxin YafQ. YafQ and DinJ together bind their own promoter, and repress its expression. There are 2 operators with imperfect inverted repeats (IR) in the dinJ promoter, YafQ-(DinJ)2-YafQ only binds to the first (most upstream) of them to repress transcription; binding to a single IR is sufficient for activity in vivo and in vitro. DinJ alone is as potent a transcriptional repressor as the heterotetramer and also only needs to bind 1 IR to act; Cell death governed by the MazE-MazF and DinJ-YafQ TA systems seems to play a role in biofilm formation.
Sequence:
MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVAREKALPFDLREPNQLTIQSIKNSEAGIDVHKAKDADDLFDKLGI
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Subcellular Localization:
Cytoplasm.
Sequence:
MTWHILGAGSLGSLWAARLGRAGLPVRLILRDRQRLRRYQQAGGLSLVEDGQASLYPIAAETPDGGQPIQRLLLACKAYDAEEAASSVAHRLAGNAELLLLQNGLGSQQAVAARLPRSRCLFASSTEGAFRDGDFRVVFAGRGHTWLGDPRDTNAPAWLTQLSQAGIPHSWSDDILERLWRKLALNCAINPLTVLHDCRNGGLRQHPEEIAALCDELGQLLHASGYDAAARSLLEDVRAVIDATAANYSSMHQDVTRGRRTEIGYLLGYACQHGQRLGLPLPRLGTLLARLQAHLRQRGLPDR
The following text describes a protein:
Function:
Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle. Acts as a potent cell cycle inhibitor, regulating a hydroxyurea-dependent checkpoint in leaves. Essential to activate a high-light-dependent cell cycle checkpoint.
Sequence:
MEEKNYDDGDTVTVDDDYQMGCTTPTRDDCRIPAYPPCPPPVRRKRSLLGFGKKREPPKKGYFQPPDLDLFFSVVAASQAAT
The following text describes a protein:
Function:
Efflux pump; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria. May be involved in the secretion of E-ascladiol to be converted to patulin by the secreted patulin synthase patE (By similarity).
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MAESTAHTSPSLNDKEREVDQGILSDESGPAEEVKETPDQERSVQGVRWLLICIAVFSANLLYGLDNTIVADIQGAVAGTFEEYAQLGWLGVGFTLGSVVFILPLGKAYAIFDTKWLFIGCLTMFAAGSALCGGAPNMDAIIVGRVWAGAGGAGMYLGNLNLITILTTPKEQPVYVGLVGLIYGVGCILGPIIGGAFADSSATWRWGFYINLIIFGIMAPIYVFLLPSLPRPAGEGRSFINRLRELDWVGTVLSAGMHVSFILFIVFGGVMWPWTDGRNIALYVVAAVTLIAFALSQYFCVLTDKENRLFPGEFLRNPTMIALYVLMACGGAALFVAVYYIPLYFQFVHGDSGIMSAVRLLPFICFYVATILLCGWLMPKTGYYVLWYLLSGIFMVIGSATMYTVKYDTKVANIYGYSILLGLGMATTQAAYAVGPSLVTPDRVAESIQFMNIGQGQSQLLGLAIASAIFQSETLSGLNALLAGKGYSQGDIQGAIAGARSTLLTELPADLKTKALDVIVHSIDDVYVMAIAAGALYVIASCFLPWRRF
The following text describes a protein:
Function:
Transcription factor that is responsive of the nuclear import of SHOOT MERISTEMLESS (STM).
Subcellular Localization:
Nucleus.
Domain:
The SR/KY and BELL domains are responsive for the interaction between the TALE/BELL proteins and the TALE/KNOX proteins.
Sequence:
MAVYYPNSVGMQSLYQESIYLNEQQQQQQQASSSSAASFSEIVSGDVRNNEMVFIPPTSDVAVNGNVTVSSNDLSFHGGGLSLSLGNQIQSAVSVSPFQYHYQNLSNQLSYNNLNPSTMSDENGKSLSVHQHHSDQILPSSVYNNNGNNGVGFYNNYRYETSGFVSSVLRSRYLKPTQQLLDEVVSVRKDLKLGNKKMKNDKGQDFHNGSSDNITEDDKSQSQELSPSERQELQSKKSKLLTMVDEVDKRYNQYHHQMEALASSFEMVTGLGAAKPYTSVALNRISRHFRCLRDAIKEQIQVIRGKLGERETSDEQGERIPRLRYLDQRLRQQRALHQQLGMVRPAWRPQRGLPENSVSILRAWLFEHFLHPYPKESEKIMLSKQTGLSKNQVANWFINARVRLWKPMIEEMYKEEFGESAELLSNSNQDTKKMQETSQLKHEDSSSSQQQNQGNNNNNIPYTSDAEQNLVFADPKPDRATTGDYDSLMNYHGFGIDDYNRYVGLGNQQDGRYSNPHQLHDFVV
The following text describes a protein:
Function:
Required for the development of the antennal, intercalary and mandibular segments of the head.
Subcellular Localization:
Nucleus.
Sequence:
MIDAACNYLNPYAQQHQAQQQQHAQHQQHAQQQQHHLHMQQAQHHLHLSHQQAQQQHMQHLTQQQQQQQQQQQQQQQQQQQQQQPQQQQHDFLSAAALLSAPPSLSGSSSGSSSGSSPLYGKPPMKLELPYPQASSTGTASPNSSIQSAPSSASVSPSIFPSPAQSFASISASPSTPTTTLAPPTTAAAGALAGSPTSSSPSSSAASAAAAAAAAAAAAADLGAAAVASAAYGWNTAYSGLGPARSQFPYAQYASDYYGNAVGMSSSAAWFSHQERLYQPWSSQSYPGFNFDDIAFQTQLQRRSVRCTCPNCTNEMSGLPPIVGPDERGRKQHICHIPGCERLYGKASHLKTHLRWHTGERPFLCLTCGKRFSRSDELQRHGRTHTNYRPYACPICSKKFSRSDHLSKHKKTHFKDKKSKKVLAAEAKEQAAAAIKLEKKEKKSGKPLTPPVEFKQEQPDTTPLVNYAPYANLYQHSTSAGSSVNPPPPPPPLFQQQMTTTTSSAAASFVEQPWSSSSSRAIQPATTSASSSSSSSASSPAAAVVSAIGSASSPAASATALAQHHYAALAMQSESQLAAEYGLTMSGLASGASQDSSSSCHMKSEYAASYPADFGAGTASYGYPHPHPHHHNAWAAAYHPHATA
The following text describes a protein:
Function:
Ethanolaminephosphotransferase that catalyzes the transfer of phosphoethanolamine (PE) from CDP-ethanolamine to lipid acceptors, the final step in the synthesis of PE via the 'Kennedy' pathway. PE is the second most abundant phospholipid of membranes in mammals and is involved in various membrane-related cellular processes. The enzyme is critical for the synthesis of several PE species and also catalyzes the synthesis of plasmanyl-PE, a lipid required for proper myelination and neurodevelopment, from 1-alkyl-2-acylglycerol.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSHLHCPHTTFNKAYRSVLCFTSLLFSSQYSAVDTNPLSVYVMQPIWNKIIKIVPLWIAPNLLTFSGFIMILVNYFLISFYDWDYTASGTSPGRVPTWVWLFSAFTTFCAYALDSIDGKHARRTQSSSPLGELFDHGLDSWATSIFVLSFFSVCSRDNGKTGVSVYTMYMYLSIVLFNFMCSHWEKYNTGVLFLPWGYDLSQVLITAYLLTGIVGVEVWQKPFLFGYYITDVLVILLIAHLRKTLKNDSLYEGLLPLVSPLLLFMLLTVWVVLSPGNILAKQPRLFLWMVGVTFSNVICKVIICQMSSTQPELLHWFLFPLALVVYAAISGLLGRAEEAVLGAFTALVTAAHVHYGICVVRGWGELYHFCHLLAFELLL