lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
Subcellular Localization:
Cytoplasm.
Sequence:
MEKKFRGEIPFWLKNKKNNLVYICSSNRNIDDYFFVLKDFYKGKILRIKKENEARELKKYNYDLLELINSNEKFIILISLDYFLEDYYSEANSIFIEKGKNLNIKDLEEKLIDADFEKTYMVAQRKEYSIRGDILDIFNINQDNPVRIEFFGNEVDRITYFDINSQLSIEKKDSIELYIDNNKNKKDIFSLMSMNKNKIEYYYENNDILQAKIKRLINENLDREEDILNKIAELSKIGIQIEIQKFSEEELKQFEVIDRVKKLSENTKITIYSEEATRYKEIFKGYPVKFEKYPLFEGYKTDDKLILTDREIKGIRVKRERVEKKALRYKTVDEIKEQDYVIHENFGVGIFLGLENIEGQDYLKIKYADEDKLFVPVDSINKIEKFINISDVIPEIYKLGRKGFKRKKAKLSEDIEIFAKEIIKIQAKRNLGNGFKFSKDTVMQEEFEETFPFTETPAQSKAIEDVKRDMESGKVMDRLICGDVGFGKTEVAIRATFKAVMDGKQVILLVPTTVLAEQHYERFSERFKNYPVHIEILSRVQSKKEQTESLKRIENGSADLVIGTHRLLSDDIKFKDVGLLIIDEEQKFGVKAKEKLKKIKGDIDVLTLTATPIPRTLNLSLLGIRDLSVIDTSPEGRQKIHTEYIDNNKNFIKEIILSEISREGQVFYIFNSVKRMESKVKEIRELLPEYIKVSYIHGQMLPRDIKKNIQDFENGNVDVLVATTIIENGIDIENANTMIIEGVEKLGLSQVYQLRGRIGRSTKKSYCYMLTNENKTKNAKKREESIREFDNLTGIDLAMEDSKIRGVGEILGEKQHGAVETFGYNLYMKMLNEEILKLKGEAEEELDEVDVELNFPRFLPDNYIEKNEKVKIYKRALALKNLDELENLYNELEDRFGKIKSEAKGFFDFIKIRIIARDLGITTIKQDKENKDRILINFNEKKINVDKIIYLLSNKKIMYSKFTRTIGYNGDIFEFFKLYSS
The following text describes a protein:
Function:
Degradation of glucosinolates (glucose residue linked by a thioglucoside bound to an amino acid derivative) to glucose, sulfate and any of the products: thiocyanates, isothiocyanates, nitriles, epithionitriles or oxazolidine-2-thiones.
Subcellular Localization:
Vacuole.
Sequence:
MNNLPIFVFIIILQSLILSSSCLYQNSSQNILQDSSPFPSDFLFGTASSAYQYEGAFLTEGKGLNNWDIFTHENPGKIRDENNGDMAVDQYHRFKEDIQLMTSLGLNGYRFSISWSRVLPRGRFGGINYSGIKYYNRLIDALISRGIKPFVTLNHLDYPQELENRFQSWLSPEMQNDFGYLADICFKHFGDRVKHWTTLNEPNQQIILTHLKGTFPPSRCSLPYGNCSQGNSEREPFIAAHNMILAHAKAVHIYRSKYQILKIHKLYTNSSPNNPPPPPPHPLIKINSYFLCFIIRGRFGGINYSGIKYYNRLIDALISRGIKPFVTLNHLDYPQELENRFQSWLSPEMQNDFGYLADICFKHFGDRVKHWTTLNEPNQQIILTHLKGTFPPSRCSLPYGNCSQGNSEREPFIAAHNMILAHAKAVHIYRSKYQVKQRGIIGIVVQTSWFEPISDSIADREAAERAQSFYSNWILDPIIYGKYPKEMVNVLGSALPRFSRKEVENLKQLRLDFIGINHYTSYFIQDCLFTTCNAGDGASKAQGFALKLDRKGNVSIGELTDVNWQHIHPEGFRKTLNYLKNRYHNIPMFITENGFGDLQKPETTLTELLNDTKRIQYMSGYLDALQSAMRDGANVKGYFAWSLLDNFEWLYGYKLRFGLFHVDYTSLKRTPKLSASCLCTARSSLPSCGTN
The following text describes a protein:
Function:
Involved in strigolactones biosynthesis by cleaving asymmetrically a variety of linear and cyclic carotenoids at the 9-10 double bond. Produces one C(13) beta-ionone and the C(27) 10'-apo-beta-carotenal. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds. Can rescue the phenotype in the Arabidopsis max3 mutant.
Miscellaneous:
MISCELLANEOUS: The branching phenotypes of the ccd7/max3 and ccd8b/max4 mutants can be rescued by exogenous treatment with the synthetic strigolactone analogs GR24 and 4BD.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MATQAIAPMHAAVVHRHHVLPPRRCVRRRGVFVRASAAAAAAAAETDTLSAAFWDYNLLFRSQRDECLDSIPLRVTEGAIPPDFPAGTYYLAGPGIFSDDHGSTVHPLDGHGYLRSFRFRPGDRTIHYSARFVETAAKREESRDGASWRFTHRGPFSVLQGGKKVGNVKVMKNVANTSVLRWGGRLLCLWEGGQPYEVDPRTLETVGPFDLLGLAAADDNKATNASAARRPWLQEAGLDAAARLLRPVLSGVFDMPGKRLLAHYKIDPRRGRLLMVACNAEDMLLPRSHFTFYEFDAHFDLVQKREFVVPDHLMIHDWAFTDTHYILLGNRIKLDIPGSLLALTGTHPMIAALAVDPRRQSTPVYLLPRSPETEAGGRDWSVPIEAPSQMWSVHVGNAFEEANRRGGLDVRLHMSSCSYQWFHFHRMFGYNWHHKKLDPSFMNAAKGKEWLPRLVQVAIELDRTGECRRCSVRRLSDQHARPADFPAINPSYANQRNRFVYAGAASGSRRFLPYFPFDSVVKVDVSDGSARWWSTDGRKFVGEPVFVPTGGGEDGGYVLLVEYAVSKHRCHLVVLDAKKIGTENALVAKLEVPKNLTFPMGFHGFWGDE
The following text describes a protein:
Function:
Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
Subcellular Localization:
Cytoplasm.
Domain:
IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
Sequence:
MSEKPQKSQKSEVKDYSKTLFLPQTEFPMRAGLPQREPEILKYWNDIGLYDRLRQEAEGRTKFVLHDGPPYANGNIHIGHALNKILKDVVTKSQQMLGFDSNYVPGWDCHGLPIEWKIEEENYRKKGKQKPDFRDSAAMVAFRKECRAYATHWINVQREEFKRLGIIGDWDHPYQTMSYPAEAQIARELMKFAANGTLYRGSKPVMWSVVEKTALAEAEVEYEDYTSDMVWVKFPVTSPAHGALASASVVIWTTTPWTLPGNRAISFSPKIAYGLYKVTDAPADNWAKTGDLLILADALAAEVFKQARVTTYEKVRELPADTLDAVECAHPLKGFSGGYEFTVPLLPGDHVTDDTGTGFVHTAPGHGREDFDVWMANARELEARGINTTIPYTVDENGAFTDHAPGFVGKRVINDKGEKGDANEAVIKALIDAGKLLARGRLKHQYPHSWRSKKPVIFRNTPQWFIAMDKDISANGHAKKGDTLRARALHAISVTQWVPPSGENRINGMIANRPDWVISRQRAWGVPIAVFVREKSDGSAEILQDEIVNQRIAEAFMEEGADAWYMDGARERFLGSRASEDWKKVDDICDVWFDSGSTHAFVLEDRQNFPQLGNIVRKVDGGSDTVMYLEGSDQHRGWFHSSLLESAGTRGRAPYDIVLTHGFTLDENGRKMSKSLGNTVEPQKVIKDSGADILRLWVCATDYADDQRIGPEILKNTIETYRKLRNSIRWMLGTLHHFKPSEKVAYAEMPELERLMLHELAGHAETVRNAYAAFDYKTVVASLAAFMNSELSAFYFDIRKDTLYCDPPSSPARKAALTTIDLLCDAILKWLAPILSFTTDEAWRMFRPNAEPSVHLTLFPADIEKLRDDKLAAKWETIRNVRRAVTGALELERAAKNIGSSLEASPVIYVADRDMLATLFDTDLAEVCITSNYEVRESEAPASAFRLDAVPGVAVVVEKAVGTKCARSWKISQTVGEDPEYPDVTPRDAQALREWKALGVGV
The following text describes a protein:
Function:
Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
Sequence:
MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVAAEAVTRTGLNGTSIAAIGITNQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKKQGLEAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKLAFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPEVKASSEIYGHTKTTVFASKIPLAGIAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESKNNLVTTIAWQIGDDVQYALEGSIFIAGAVVQWLRDGVGLIKTAAEIEALAASVPHTDGVYLVPAFAGLGAPHWNARARGSVFGVTRGTSAAHLARAALDAIAYQSLDVLAAMEADSGISIGELRVDGGASANDLLMQFQADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRDQWQLDRRFAPSMPKEQVEQRMAGWQRAVRAAKAWADDTQ
The following text describes a protein:
Function:
Plays a role in Golgi-associated microtubules organization and stabilization.
Subcellular Localization:
Golgi apparatus.
Sequence:
MSLDCTSHIALGAASPAPEETYDHLSEVPVTREQLNHYRNVAQNARSELAATLVKFECAQSELQDLRSKMLSKEVSCQELKAEMESYKENNARKSSLLTSLRDRVQELEEESAALSTSKIRTEITAHAAIKENQELKKKVVELNEKLQKCSKENEENKKQVSKNCRKHEEFLTQLRDCLDPDERNDKASDEDLILKLRDLRKENEFVKGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSLALPDYEIIKCLERLVHSHQHHFVTCACLKDVTTGQERHPQGHLQLLH
The following text describes a protein:
Function:
Microtubule-associated force-producing protein that may play a role in organelle transport (By similarity). Has ATPase activity. Involved in synaptic transmission (By similarity). Mediates dendritic trafficking of mRNAs (By similarity). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell projection, dendrite. Note=Abundant in distal regions of dendrites.
Domain:
Composed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.
Sequence:
MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVIQHLEVELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNITPVVDGISAEKEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQTDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGSSNSTHYQK
The following text describes a protein:
Function:
Catalytic component of the NEM1-SPO7 complex which acts as a phosphatase and dephosphorylates the phosphatidic acid phosphohydrolase PAH1. Essential for the formation of a spherical nucleus and meiotic division. The NEM1-SPOo7 protein phosphatase is required for efficient mitophagy under prolonged respiration, as well as for reticulophagy and pexophagy.
Miscellaneous:
MISCELLANEOUS: Present with 377 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Sequence:
MNALKYFSNHLITTKKQKKINVEVTKNQDLLGPSKEVSNKYTSHSENDCVSEVDQQYDHSSSHLKESDQNQERKNSVPKKPKALRSILIEKIASILWALLLFLPYYLIIKPLMSLWFVFTFPLSVIERRVKHTDKRNRGSNASENELPVSSSNINDSSEKTNPKNCNLNTIPEAVEDDLNASDEIILQRDNVKGSLLRAQSVKSRPRSYSKSELSLSNHSSSNTVFGTKRMGRFLFPKKLIPKSVLNTQKKKKLVIDLDETLIHSASRSTTHSNSSQGHLVEVKFGLSGIRTLYFIHKRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLESSFPSSFSKRYYRSDCVLRDGVGYIKDLSIVKDSEENGKGSSSSLDDVIIIDNSPVSYAMNVDNAIQVEGWISDPTDTDLLNLLPFLEAMRYSTDVRNILALKHGEKAFNIN
The following text describes a protein:
Function:
Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure.
Subcellular Localization:
Vacuole.
Sequence:
MFSHPPSTTSSNLAHGNRVAEPINSLCIPLTEERDSPSKHTVYKLVMKGQVREWSVWRRYSEFDALNRQLLALFPDPPSLSAQLPNKSLSLFSNSLIGFATDPAKVEARRIALEAYLQAILYAKDTRWRRSDIWMDFLNIPGSLRASDAKKSKEDATGHVLVDSDNWIHNFHDLQLLVTDIRTEINARTRSAETYDASTVQSKNVQLRKSTSLATDRLNALESALKISSDTVNSGSRPVGMTAAYATKGEIRRRQDLLANLKEDIAQVTRAALTTPTMQPRSAKESSDRQNLFGTTSANHSPFSRIATSVKTMRKFGVANVQPQETDETRSLDNSGILQLQRDTMHQQDAELDSLAFVVQRQREIGLTIGKELDSQNQLLDEVNTSVNRVETNLKTSDKKLGRILGKK
The following text describes a protein:
Function:
Catalyzes the ferrous insertion into protoporphyrin IX.
Subcellular Localization:
Cytoplasm.
Sequence:
MDLINEKLNNLENNATKSPKEAVILLNMGGPNSLYEVGVFLKNMFDDPFILTIKNNFMRKMVGKMIVNSRIEKSKKIYEKLGGKSPLTPITFALTERLNKLDPSRFYTYAMRYTPPYASMVLQDLALKEVESLVFFSMYPQYSSTTTLSSFNDAFNALKSLETFRPKVRVIERFYASKKLNKIILNTILNTLNNRKSQDFVLIFSVHGLPKSVIDAGDTYQQECEHHVSLLKELMQQKNTPFKEVLLSYQSKLGPMKWLEPSTEELIEKHRKSHIIIYPLAFTIDNSETLYELDMQYRLMAERLAVKEYLVCPCLNDSIEFAQFIIERVKNLKE
The following text describes a protein:
Function:
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate, the immediate precursor of folate derivatives; Is the target for the sulfonamide group of antimicrobial drugs. Sulfonamide drugs act as pABA analogs, they inhibit the reaction by acting as alternative substrates, leading to a 'dead end' sulfa-pterin product.
Miscellaneous:
MISCELLANEOUS: Reaction proceeds via an ordered binding mechanism, with DHPPP binding to the enzyme first, inducing a structural change which forms the pABA-binding site; MISCELLANEOUS: One or two residue insertions within this gene are responsible for sulfonamide resistance in streptococcal clinical isolates. Sulfonamide-resistance mutations in the second loop region have a drastic effect on pABA binding.
Sequence:
MSSKANHAKTVICGIINVTPDSFSDGGQFFALEQALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDTWKSQVAEAALAAGADLVNDITGLMGDEKMPHVVAEARAQVVIMFNPVMARPQHPSSLIFPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK
The following text describes a protein:
Function:
Neurotoxin that produces dose-dependent hypolocomotion and hyperalgesia in mice. May directly act on the central nervous system, as it is 6500-fold more potent when administered intracerebroventricularly than intraperitoneal.
Sequence:
MTGILPGQDPMKDLCEEVTCSFCLDYFKDPVILDCGHNLCRACLTQRWEKPGHTETSCPYCREIVSQKNLKTNQKLANIVEKVRILNPQGPKKAKGKEGVCGNHQKPLKLFCKDDETPICETCDRSKEHQDHRMIPLGMAAEDYKLLMGHRQDDLVKEREKIVEYKAETEKEAQDLLKQIKTKMETTLDEITEIRQFLDKQETHLQAQMEELKKQITRERDEHFILLSRELSSLENLIQELKERCQQPPAEMLQDVRNLLQRCEEKQVSEKPVAFPPELKWKIWEFCDINSFLVAVMKPFRDALLTGLELQKANVALDPDTACDWLILSEDHKSVRLGDEPQDLPDNPERFSDRVYVLGREGFTSGRHFWEVVVEGEGEWAVGVARESIRRKGAIHSGPKEGIWAVGKWVGMYRAPSIPSSTDFLLSEKTKRVRVCLNYASNQVAFYDADTGDRICIFSDVPFSVETVLPFFYAHKNAYLRILP
The following text describes a protein:
Function:
Probable transcription factor. Required for the establishment of a subset of imaginal tissues: the abdominal histoblasts and the salivary gland imaginal rings.
Subcellular Localization:
Nucleus.
Sequence:
MKTELRSCAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGAKCSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHYLETVEGGTTSSDEGCDGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVTQVWFQNSRARQKKHIHAGKNKIREPEGSSFARHINLQLTYSFQNNAQNPMHLNGSKAGLYPTHESSMDELSQDSSVHCMPSEV
The following text describes a protein:
Function:
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Subcellular Localization:
Nucleus.
Sequence:
MMESIEHRTVSGNTTANSRVMLLPLMDNLSDQSVDVRVLSLPSPATGLASAFLLVPTTKTHCKTPALFQVHLVEAPFKSWAIDNQIIADGSLYVTTPYDPLFVLAPILDFHRQKSTESPGRFMQWTDLVVDDNFPDFALLASTLDEHIISSICDINDIENIGLFYRLSDSKFLAWLNAKVDRLVVKASNGSIPAFIPLIEDAKLLHNTPADTLLYQRIAFQTIAEHLTPKWKEMFLDHLGFKNDPIWSKQHVYFNSEITKRTASSLPNTSTKPTKQIKLSRGQHNIAKASKSGMKPLTSFFKPATTKPSSK
The following text describes a protein:
Function:
Binds to F-actin in a calcium independent manner. Binds to the filaments along their length.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MADVSSTELKAAYDEVLADSNDTNWCLFKYEGKNKIVLSGKGSGGFAELAQEINQPSERLYAYLRVVSGDDESKRSKFVFISWCGEEVGPLAKANVSVHKASVKQVIKNIGVEVHYTVADDLNEEELMTKVRKSSGADYSGNKSTN
The following text describes a protein:
Function:
Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule.
Subcellular Localization:
Cytoplasm.
Sequence:
MAGAACCFSDEQFREACAELQKPALTGADWQLLVEASGITIYRLLDQPSGLYEYKVFGVLEGCSPALLTDVYMDLDYRKQWDQYVKELYEKESDEQMVAYWEVKYPFPLSNRDYVYTRQRRDLDVDRRKIYVVLAQSISAPQFPEKSGVIRVKQYKQSLAIESDGKKGSRVFMYYFDNPGGQIPSWLINWAAKNGVPNFLKDMVKACQNYHKKT
The following text describes a protein:
Function:
Along with the bacABCDEF operon, BacG is involved in the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacG catalyzes the stereoselective reduction of exocyclic-delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP), adding a pro-S hydride equivalent to C4 position to yield tetrahydro-hydroxyphenylpyruvate (H4HPP). Although the 3Z,7R-ex-H2HPP isomer is kinetically disfavored by BacB and produced in a smaller quantity than 3E,7R-ex-H2HPP, it is the preferred substrate for the conjugate reduction reaction of BacG.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASEEASYITGQQISADGGSMKSI
The following text describes a protein:
Function:
Involved in spore wall maturation. Catalyzes a two step reaction that leads to the LL-dityrosine containing precursor of the spore wall.
Sequence:
MTFTSNLPSSSEQSISPPASSFSSSTDTLKDIDIPHNGADLSTYSKFLALYCRSDKCDDFYSLEEKQNCKFGDQWLDFINTIHNLDFSESEVSGRVSERILPASLANKFTNNLGVAIKISEYTRDDERQIRGCVTTVENENSFNNWFVYHILDQSQLSLSEHPIVTKEVKYHELFADFFEKNLKNTIVNDQWNFGGRDYFIERSRYFTDRYLRIECILPAFPCKSSNEQKVYGSVPDKGEELALKRLIKATQDLVKIYPPGMKIWIVSDGHVFSDCIGVDDDVVSTYTTKLHELYKRVAIPGVDAIGFCGLNDLFFSGAASKVFDPKWVSDVEVAHYTGTQICPKSDLSRQILMKGCDTDAGRLRKQIAIEGHPRLHLYRGFSRFMMEDLSLLEHFQSYSRKKFKKIISMIAFNMIKRNDAYSNLVELIFPHHLRISIHAHTNSGPKFGIKVISNEQCSIVSSLEDLDEPKFEDFLHIPTPWHNCVVKVEDEKEKYFLTKSKVVKEALEKGMYDGVWKDTRFDIGEGGHFVIKKIS
The following text describes a protein:
Function:
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MFLKILLVILSYLIGSIPSALIVGKLWKGIDVRNYGSGNLGATNVLRVLGWGPAVIVAVMDVGKGILAVYLAQSFLHSDYLFVLLCVIAAVIGHSFPIFAGFRGGRSVGVSFGILFYLFPKSSLIIFFIAIIIVAVTQYKSVASITSALIYPFLLYHIEKPPMEYFIGVILVCLFIIYRHIPNIKRLIKGEEHKISWKVRR
The following text describes a protein:
Function:
Catalyzes the key reaction of chlorophyll catabolism, porphyrin macrocycle cleavage of pheophorbide a (pheide a) to a primary fluorescent catabolite (pFCC). Works in a two-step reaction with pheophorbide a oxygenase (PaO) by reducing the C20/C1 double bond of the intermediate, RCC. Belongs to the chlorophyll catabolic enzymes (CCEs) (By similarity). May play a role in senescence and response to wounding.
Miscellaneous:
MISCELLANEOUS: Plants silencing RCCR1 exhibit lesion-mimic spots on leaves.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MLQLRSPPPATSSPSSAVSFPTLAPRLLPLRRRRRGAGSQLGGKTSSAVRASSAAAPGATEPEVMVEVAHREVARALASLAEARLGARLLPSAVPPDVAEFRSGGGAGNAVGSLDVRRGAPGSTIDFMLQSSLHCKVPNGAIDITSLLIFLNASTDAPHFLMEFIQGSPTSIVVLLDLLPRKDLALHPEYIERYYENTQVDKQREKVEELPQARPYRSRSLFVRSTFSLTAILMSIDCGQGGEGTLEEIVRGQLATAARALLQIWLDSCADHTSEMEEGERENMIKRDQIVRSKSIEVDLTSNLPRMFGPDVADRVIAEIQKAFGVQEA
The following text describes a protein:
Function:
Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MALGVPISVYLLFNAMTALTEEAAVTVTPPITAQQGNWTVNKTEADNIEGPIALKFSHLCLEDHNSYCINGACAFHHELEKAICRCFTGYTGERCEHLTLTSYAVDSYEKYIAIGIGVGLLLSGFLVIFYCYIRKRCLKLKSPYNVCSGERRPL
The following text describes a protein:
Function:
Pore-forming subunit of the CatSper complex, a sperm-specific voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization.
Subcellular Localization:
Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Specifically located in the principal piece of the sperm tail.
Sequence:
MDQSSRRDESYHETHPGSLDPSHQSHPHPHPHPTLHRPNQGGVYYDSPQHGMFQQPYQQHGGFHQQNELQHLREFSDSHDNAFSHHSYQQDRAGVSTLPNNISHAYGGSHPLAESQHSGGPQSGPRIDPNHHPHQDDPHRPSEPLSHPSSTGSHQGTTHQQYHERSHHLNPQQNRDHADTISYRSSTRFYRSHAPFSRQERPHLHADHHHEGHHAHSHHGEHPHHKEQRHYHGDHMHHHIHHRSPSASQLSHKSHSTLATSPSHVGSKSTASGARYTFGARSQIFGKAQSRESLRESASLSEGEDHVQKRKKAQRAHKKAHTGNIFQLLWEKISHLLLGLQQMILSLTQSLGFETFIFIVVCLNTVILVAQTFTELEIRGEWYFMVLDSIFLSIYVLEAVLKLIALGLEYFYDPWNNLDFFIMVMAVLDFVLLQINSLSYSFYNHSLFRILKVFKSMRALRAIRVLRRLSILTSLHEVAGTLSGSLPSITAILTLMFTCLFLFSVVLRALFQDSDPKRFQNIFTTLFTLFTMLTLDDWSLIYIDNRAQGAWYIIPILMIYIVIQYFIFLNLVIAVLVDNFQMALLKGLEKVKLEQAARVHEKLLDDSLTDLNKADANAQMTEEALKMQLIEGMFGNMTVKQRVLHFQFLQLVAAVEQHQQKFRSQAYVIDELVDMAFEAGDDDYGK
The following text describes a protein:
Function:
Regulator of G protein-coupled receptor (GPCR) signaling. Probably acts by regulating the activity of some 'R7' family protein (RGS6, RGS7, RGS9 and/or RGS11).
Sequence:
MNRWQRSVVEIQTRKRQVNECERAQVALSKVTACFQQMSTSLGSNVDGSFLREEMEETRTVAHKICSGLHRRLLSLLMEIDQGQEDKEQVERLWVIFLSSLENFQQDLKKVKVLQEIFPLTQRKDRQALVITGLAGGTSEVAARAAMVQTPWLSVEVTVSPDLKTHIEEIDVLLEEMLQRVNVPLWSVEPTQEAWVEGSSTPGVGQEEDESLEEMMEVEVVSQNKTSGCCHHHNCKVGCLLCLLS
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MNTNKKNNTILFTIFGIVLIVVVGLLVFFANRPKTDDSSASSTNTSSSSQKVNYPTNYTLNAAVKNSSTALNDLTLPQLSTTVGEDEAEVQIKTSAGNINIKLFPKLAPNAVQNFLVLAKHGYYKNNEFFRVIKDFMIQSGDPSNKGTGTASIFGGKTFDTEISNQLYNIRGALALANTGQASSSSSQFFIVQNPQDMTSQIQDKSKYPQKIIDAYKKGGYPSLDGSHTVFGQFISGMDVVDKIAKADVKTNSSGESSAPIDPVKIKSVKILKDWKF
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MADGEAERENGPPGPDINTEMPRLEESLRELERLLQEESAKGEAAQASSEFCQRFCQTLFEYAEKWKAPEDSLSLLEVYTVAIQSYAKARSYLSSDCENVALVVERLALSCVQLLLCLPHELPDDHWEKFQYSIKAAHMLLTENGSHELSILYNLSQETGVWKNPVLERLINLEPLDQAQVIDQFLVSEAPILLEMRIKQLLKLTKVASATTLAKLCSDHLEMSKKGNFTQLYLTCLCAASPNIKLIEEIAKVDCKDALDMICNLESEGDEKTSLILCAAFLSRQLQFGEMYCAWELTLFWSKLQRRVDPSIQIYLERCRQLSLLTKTVYHIFFLIKVIQSETEGAGLPTCIELCVRALRLESSENSKVKISICKTISCLLPDDLEVKRACQLTEFLLEPTVDAYYAVEMLYNQPDQKYDEESLPVPNSLRCELLLVLKTRWPFDPEFWDWKTLKRQCLALMGAEASIVSSIDELNDNEAYDQTDDYQEVTQISCLNGLDCFDNVNANNVKEEEKQKKKNIKKMRERGYISERFRNWQAYMQYCVLCDKEFLGHRIVRHAQKHFKDGIYSCPICAQQYSSKEYFVPHVTFHVKQSCKERLETMKPLRRIGKLPKKAPASKSKKPVTVSKQERPIKKNSLYLDDFIVFNDNDKSDDDEKNNQSDIAPKEEPTLINEFACPVQLCKKGFKYFKNLIAHVRGHKGDEEATRFLEIQSKKVVCQYCRRQFVSLAHLNDHLQMHCGDQPYICIQMKCKASFETYADLLSHRKEHRVFRARCMFPKCGRIFSAAYMLFDHEAQHYNTFTCKYVGCGKIYHSQLQLEKHLSEHVPEERLLESKSNMAPQQIEMPGTVVMANKQPTQDCPVETNFEPGHENHSNHSSAVLPQKEESIVSNGIQQTPHLLDHHLPPITEVLPFASLLNQMLPSSSAILHQTLPPEADMLNPSDLPVHPSSNVKLQSAPDGCPEIVLNQSKLVANNLNENKQLTRLHFEEPCLPVFEGCKTSCPVKLNKENVNSSDAVENKMEVLSANSVESQVSSLMPFEANNQASQLCENNLDMSGFNDNSKPENALSLSLETSSMLTNVLPSVGKTVPVQTSPPQKFKCSVEACTRIYNSVQSMGKHMKTAHPDHYDDFKMERKNRKKLKRANSGIPSVEDKPTYCILPEEGCSNPVFQPQVQSGSNPNFCSQLQHIPNPIIPSHLENLNPILSSVESIISQSLSKNVADSLLGTDVGNLTSTTLTSQLEDLAKVVLPLKFENGSDPFLPMPTENDPLPVMSSLSGVTVFTQLGSNTNHDHVLSGGEAANSLFLKEERDAESSFSKQADNADIDASFNLDKSSTMLTNTIETKNGNERTSRNRERKPRHSSRPKCPAIIRDGKFICSRCFRAFTNPRSLGGHLSKRAVCKPHNEYDGSQVVPQVDGQASVLASMILSSSPKHTLQSPTQTYSPEVSIKEEPFLPTISSNNQTTQFFSSCVTRDLDETKKVMQTPEIVKNRLLNVTSGGSLNMSSDTTPLTAFMSPTSIKMEESHRILHSDLNNFNKVATVAEGSMFNNVENGLCSNASLNAGNENNCLSTPVSSTRVSVISGPQNSSSTAKKKKCGGTKKKKKNPDVTPEFNASNELAKNLLAAVGGLPQNVGGSLQMPNEMQPNFLSYSSELIENIAKHLNNTDKQLFLSCINDSIKAHADANTICQTPDKPEKCDSLDMPTFASNSKDHSEVQLQTEGLNCQAAEVFSVNGNAENACFSLRQSQNTINQDIDTISRDMQNIISATVNDSPNGTLNIPICSASPTQEADPSPDAHILEIMDLVQKLQLVDNVRFENIGIDSVPACPDYLPMTSSVIVPNPRLNVVEEPDVSKSLPDKGNAKPFICQEVDCTYCAMTKDALFKHYAKVHYYTQEKIMEIKKHQLKFAPFKCVVPSCTKTFTRNSNLRAHCQSMHNFTPEQMVKLKIKRAYGRKSGEIACANIQELPHTIPEMEQSVDEPQELTGQHQETPTVERVEAPKEQEPISPQIPSKPASHILQALSQKCKRGSKVRRKTKELIDKVDVQKDIKPADQGFSTYKPYQCVHQGCTAAFTIQQNLMLHYQAVHKSVSKFSLEEGEESENGFSRKEFRCMETDCSRIFQEVGSLIQHYMKLHEMIAEEIENVLSVINIGEFKCDQLNCASLFSSCTSYIEHLEEVHEIKRHIKMDGEEMYKCDCEGCDRVYATRSNLLRHIFNKHNDKHKEHLIRPRKFSLSDQDTTDEKPMKEKPRVPKQKCETEGNNDLKVKGSKGCLVDRDLKIEQGQTKQETLPLKYGRHTYSLKPKDAAFVECSDNLAKQYPCMIRGCTSVVTSERSIIRHYKCHKLSRAFILKHRNSLIVCKRRARPKSKTESTILKDGEDPNNEISSKKESVPSLLEFDESSLSTSQPSENEKDEMDELAELFISKLSNEDSTGSDSQAMTSSFVSSDFQETSSCQSEPQKETSNLKRTNKQKHVLNRKRKVVESDIQSTETSSTVSGEEVVATLPTAEEPPAFDLSSFKPLGFEVSFLKFLEASATQEEESVDLDDFKAESNAELHLIKKKIRLSVEVDEFSLESSESDPYLLFANPLHLSDMDNIKIVLDQKFNDYIDLVVKQLNELKPVVVLRRCEMLRNEPTSTSKENILAVAEEATA