lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May play a role in plant immunity.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MAAEQPLNGAFYGPSVPPPAPKGYYRRGHGRGCGCCLLSLFVKVIISLIVILGVAALIFWLIVRPRAIKFHVTDASLTRFDHTSPDNILRYNLALTVPVRNPNKRIGLYYDRIEAHAYYEGKRFSTITLTPFYQGHKNTTVLTPTFQGQNLVIFNAGQSRTLNAERISGVYNIEIKFRLRVRFKLGDLKFRRIKPKVDCDDLRLPLSTSNGTTTTSTVFPIKCDFDF
The following text describes a protein:
Function:
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the third and last glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(2)Man(9)GlcNAc(2)-PP-Dol to produce Glc(3)Man(9)GlcNAc(2)-PP-Dol.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MRLLLFVVVFIALFLSSLLVSVVVNHAQPAPYMDEIFHVPQAQSYCSYNFTYWDPKITTPPGLYLTSLCFALAAKLLVAADLCTPFYLRCTNILLMLGNFCASSAIMIRLAGACDGSTRAKLILASAATTLLPVLHFFTFLYYTDPGTVLFLQLMYLYSLFEHHWLAATFGAVAVLYRQTSIVWVFMVAACKVMAVADDRWPVEKWLKLENISCTVGQLASDPHKRVREVFDFVRDVLRDCVGYVIVGAAFVAFLVYNGGIVLGDKSAHQACFHVPQLGYFLLFSAFSGAPFFLQPNILSDFCCSLRRRAYLYAILVLASVLAVQNFSHIHPYLLADNRHLTFYLWRKVLGRSELIRFCLVPICIYAGYAMLHQLRHTSRTWRLFFLVGVFASVVPQKLLEFRYFIFPYLFFRLHLKGVTYRQIFLELMLHVTVNVAVMHLFLNKTFMWESDPSSVQRFMW
The following text describes a protein:
Function:
After shedding, the soluble form (sCD163) may play an anti-inflammatory role.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Secreted.
Sequence:
MGKNRMVLLGGAGSPGYKGFVHLGFFVVAVSSLLSVSAVTQAPEGRKKELRLAGGENNCSGRVELKIHEKWGTVCGNGWSMNEVSVVCQQLGCPTLIKAPGWANASAGSGDIWMDKVSCTGNESALWDCKHEGWGKHNCTHEQDAGVTCADGSNLEMRLVNSGDNRCSGRVEIKFQGKWGTVCDDNFSKDHASVICKQLGCGSAISFSGSAKLGAGSGQIWLDDLACNGNESAIWDCKHRGWGRHNCDHAEDVGVICLDGADLSLRLVDGVSKCSGRLEVRFQGEWGTVCDDSWDRRDASVVCKQLGCPTAITAIGRVNASEGSGPIWLDSISCEGHEPALWECKHQEWGKHYCNHKEDAGVTCSDGADLELRLVGGGSRCAGMVEVEIQKLTGKVCSRGWTLTDADVVCRQLGCGSALQTQSKIYSKTKTEATNTWLFPGSCSGNETSLWQCKNWQWGGLSCDHFEEAQVTCSGHRKPRLVGGEIPCSGRVEVKHGDTWGSVCDFDLSLEAAGVVCRELQCGTVVSILGGAHFGEGSGQIWGEEFQCSGDESHLSLCSVAPPLDRTCSHSRDVSIVCSRYIDIRLADGKSSCEGRVELKTLGAWGPLCSSHWDIEDAHVLCQQLKCGVALSTPGGAHFGKGAGQVWRHKFHCTGTEEHIGDCPMTALGTPMCSDGQVASVICSGNQSHTLLPCSSSSSVQTTSSTIAKDSDVPCIASGQLRLVGGGGRCAGRVEVYHEGSWGTICDDSWDLTDANVVCKQLDCGVAINATGSAYFGEGTGDIWLDEIDCSGKESHIWQCHSHGWGRHNCRHKEDAGVVCSEFMSLRLTNEAHRVNCTGRLEVFYNGTWGSIGSSNMSPTTVGVVCRQLGCADNGTVKPTSSDKTPTRPMWTDSVQCPKGVDTLWQCPSSPWKQRQASPSQESWIVCDDKIRLQEGHTDCSGRVEIWHRGSWGTVCDDSWDLNDAEVACKQLGCGQAVEALKEAAFGPGTGPIWLNEMKCRGNESSLWDCPARPWSHSDCGHKEDASVKCLPRMTLESQHGTGHSTLTALLVCGAILLVLLIAFLLWTLKRRQTQRLTVSSRGEVLIHQVQYQEMDSKTDDLDLLKSSGQ
The following text describes a protein:
Function:
[Elongation factor Ts, chloroplastic]: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome; [Plastid-specific ribosomal protein-7, chloroplastic]: Binds to psbD and psbA mRNAs 5'-untranslated regions (UTRs) in vitro.
Miscellaneous:
MISCELLANEOUS: [Plastid-specific ribosomal protein-7, chloroplastic]: 65 kDa protein PSRP-7 is the major form.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MLRELGRTATVKAHGRSVLRPVRGPAGRRQVAFTGVRPSVRVFAEAPAAEQAAKAIKLEDVKEGSEYEGTVTTVEEFGAFVNFGANTNGLVHISKLASGFTKNAKDVVQPGQKVTVKVLSVDAEKKRVSLELKSAVAAEASAEESDDIITEPDREGADATDDDEDVEVELEDGQVEVRADLPGFEDIPFVMEEADMDAEMSEAAIAALEADLDGAEIRYELEAPAYMEEVTGKVARIEDYGVFLEFEWNGKTLTGLLAKDEMKVPSSALSAEAQAALRAEWADTGFEMPAFVELPDDELDVKKYYQPGESVPAFVLESSLVDGRGISLTHFTDEEVSAEAVAAYEELEDDEDEELDKMMADAAGLEDEVLAFDPEALMEEDEGEEAGAAADAGDDAEYEGVSADGLEGANGNYALGATRSGLIKGKNGYQVAPMGLPSRPLNDAVTSSGLAILGTSEVDFDGDEVQLVDYWTSEAFDNIPKDVLKKLGLKMSYTEAGEAEFEERADFEATDVPFYLYGGDVESRAKEFVADLLSDDVDEAELPARAGRAPIVLAAAVQNISAAEVKALREKTGAGMMDCKKALAECAGDAEAAAEWLRKKGLSGADKKAGRIAAEGAVARYIHPGSRLGVLLEVNCETDFVAASEKFQALVNELGMIIAATDCICVSPEDVPEEVLAKEREVEMGKEDLANKPEAIRAKIVEGRLQKMRDQVALTNQATLSNPDKTVAELVKETIAAVGENVKIRRFIKYRLGEGLEKKANDFAAEVAQQTQAKAAAPAAPKKEEPKKEEPKKATVAVSAGTVKELRDKTGAGMMDCKKALAENENDMEKATEWLRMKGLAGADKKAGRIAAEGVVASYIHPGSRLGVLLEVNCETDFVAASEKFNELVNYIAMGIVAGQNVQYVSADEIPAEVFEREKQLEMARDDLKGKPDAIRAKIAEGRAKKIATEMCLLDQPFLTDPSKTVAEAIKESIAAIGEKISVRRFVKFQLGEGLEKKSNDFAAEVAAATGAK
The following text describes a protein:
Function:
May be involved in the metabolism of aromatic compounds.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MASSRLLDWMSRMRSVPQLERLIPALYLAHGSPFLMLPQSSDDEVFSNDSKLGGLHYQFLEQLGPFLLEKFRPKGIIVFSAHYESRGSVEVYSRDDENPLFYDYYGFPDYLYQIKFHSKGSKRIADQIISALKEYQIPAKTVSGDRGLDHGVFVPFKIMFPDGLNIPLIEVSMHTLDPMQLYKVGQALQSLRKEYLIVSGGLNIHTFEDLSAFNEDTAADGYKEFQLDILKAIETDKQNDRLNKLLGLQLHPYFRKAHPREEHFVPLYVAAGLGSSGKSKVVCDLYGAVSAFFGIDE
The following text describes a protein:
Function:
Involved in cytokinesis. Overexpression results in growth inhibition.
Domain:
The DAD domain regulates activation via by an autoinhibitory interaction with the GBD/FH3 domain. This autoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2 domain to then nucleate and elongate nonbranched actin filaments (By similarity).
Sequence:
MPTSDKSRQTSAGKSFFGRKLHKERPVEDRWDAHGSWESLAPPSSAAGSRSSRYSKRSSIQSVDFGADIDPSLLSTSAGPITSIPFESLSTDTQSPIPVDYLSKAETSPRKEPSPGHLAKGVGDFHQYPAWDPSAMRNHQQFSHPTGPRPPPHAAGVAMSSSATGDKGARYQQWGRPGSSAGNAGLSHHSSSTVDSSTNSRMSIDQASIHSSLSSNTRGSSYISTDGSSRTTLPSHSNDRSNYYAAMNSGRGSSAQGAIPPAQPRVQNTEQYLTRPRDDRVVDQLFLELMQKRGWQNLPEQARRQMMAYPASKKWTLVHQDRLTELQGEQKRKQKARETHGYDGPSGILERADEEGSPEWYVKKVMDDTITSKQLASLSVSLRTQPISWVKAFVEAQGQIALTNVLVKINRKKVTGPVPAPPSGDKDLDREYDIVKCLKALMNNKYGADDALAHQQIIVALISSLLSPRLNTRKLVSEVLTFLCHWAEGQGHERVLQAMDHVKNHQGETGRFDAWMRIVEVTIDGRGKMGSLVGASEEYRSGGIGMENLLMEYAVSTMILINMLVDAPENDLQLRCHIRAQFISCGIKRLLSKMEGFQYEVIDKQIEHFRENEAIDYEDLLQRESSSTKDSIEGEVKDMTDPLQITDAIASRLNGTRAHDYFLSALQHLLLIRENSGEDGLRMYQLVDAMLSYVAMDRRLPDLDLRQGLTFTVQSLLDRLHTDAEARRAYDESLEARQIAEAALAERDEMKAQVELGADGLVRKLQKQIEEQTGIIELQSRQNEMLKAELADVQRLRAQELQRNELETRELYLMLRDAQDIAASNAKKSNMGEAETDPAHMRGILDREKLLTRLEKQLERTKTQFKLEGKVWGQHDPSDRLRELREQMDGDAGPREAFEEQARLNLSLNPVGSVYRKKTYIQGMEDTATEELGQTDDEVVYAKARLVDLHRPRMDPEQATGLLGEIAAKVPKIDADDAKDEGKPTESEQPAEGAATKGDEQGVDDTVAVDKATAAPPPPPPPPPAHPGLSGAAPPPPPPPPPPPPGAGAAPPPPPPPPPPPPGGLGGPPPPPPPPPPGGFGGPPPPPPPPGGFGGPPPPPPPPPGGAFGVPPPPPPPGTVIGGWRANYLASQGAPSHAIPVMSSIRPKKKLKALHWDKVDTPQVTVWATHGTTPQEKEEKYVELAKRGVLDEVERLFMAKETRIFGGGVAAKQRKDKKQIISNDLSKNFQIALSKFSQFPAEEVVRRIIHCDAEILDNMVVMEFLQRDEMCTVPENVSKLMAPYSKDWTGPDAANTEREQDPSELTREDQIYLYTAFELNHYWKARMRALALTRSFEPDYEHISAKLREVVRVSESLRDSVSLMNVLGLILDIGNFMNDANKQAQGFKLSSLARLGMVKDDKNETTFADLVERIVRNQYPEWEDFTEQISGVIGLQKLNVDQLRTDAKKYIDNIKNVQASLDAGNLSDPKKFHPQDRVSQITQRSMKDARRKAEQMQLYLEEMVKTYDDIMVFYGEDNTDDGARRDFFAKLAAFLQEWKKSKEKNIALEEARRRTEASLARKRINVGLANGAGAAGDAPVSPATSGAMDSLLEKLRAAAPQAKDQRDRRRRARLKERHQVRVASGQKIPDLEGAEAPGSGGQNSGATDTNATDSSLLSPTIQEPEGGSSPIASQSEDVADRAASMLQDMLRNSPDPERTRRRRESAEEERRKRRLRRRNGATSGSKDSNDTTPLSPVTEPTSTQGESAEPENLSLSSPPNGEDPTLNPPTIVLSSDASDTPDDEHRPSTS
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MRNAKVDIEELRTFVEVADAGGVSPAALRLGVSKSIVSRRLLRLESELGVQLLARTTRGAALTEAGVTFRDYAARVCTEIDVAKETILPAGELRGRLRVAVPLSFGSNYFAPMMAEMARRHPQLQIHTCYSDQFVDLIAGGYDCAIRIGYLQDSNLIAKRVGPIYGKFVASPGYVKEHGSPETPEELVAHQALMQGTETWQLMDGDKIITVRPQGRFKADNGTALAAAAAAGLGIAYLPDFLTNELLASGALVSVMTRHPPPPAGAYVIRPPGQHPARKIRVLTELLIEHCNPVSG
The following text describes a protein:
Function:
Acts as a guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters (By similarity).
Subcellular Localization:
Cytoplasm. Postsynaptic density.
Sequence:
MYDLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDGVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVIDIEDGRDDDFNVSMKNAFKLHNKETEEVHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKASKQKGVNSARSVPPSYPPPQDPLNQGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK
The following text describes a protein:
Function:
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKFGYKFSNLLGTVYNKGNILFTPDGNTVISPVGNRLTVFDLVNHTSITLPIQSKYNIRRLALSPNGQILITSDESGHTLIINLTRQVVLGEYKFFKTPKSILFSPNGAIIAIAVLEKVFLFKTPIIQKQPNPLIRLSVFTHKSAVISMCWSADSLKLMIGCKNGTLLIRQGKSERVSYFQVKGSGIINCFFGNEESTIAYAVTPTGLASWDYKTNEEMEQEKLERVENGETAYLREEEMDEEKLKVITENQRLYKGRWIFKGFKKFENYGVKCKVKTVCFHLKSKLLLVGFSTGQFILYEMPGFNQLYKLNISSHGISTSAINNTGEWLAFGCSELGQLLVWEWRSETYILKQQGHSYNMNTVAYSPDGQTIATGGEDGKVKIWNTTSGYCYITFTEHEGPVTAVKYSPVSSQNVVFSAGVDGTIRAFDLVRYRNFRTFVSPNKTQFSCLAVDPSGEIIAAGSLDSFEIYVWSVRTGRLTDILSGHQSPVCELAFDPINPFLASASWDKSCKIWNIFEDREIRESIQHTSDVLTCAYSQDGKKFIVSCLDGTIQIYETSTWGQIGLIDGKNDIMGGRGYKDEILAKNNSAGRAFTKIAFTPNGECIIAGGNSKYICIYHIDQQVLIKKYSTSSNLSLDGITLDINWKRVGEFGHLDAMEKDFDSDDDLYQQNKEYLTGSSKGDLSKRTTKKKQKTTSISVSPTGRAWAVSTTEGLLIYSLDDFLFFDPTDLSIDINPDSILSELNLKNYLKSLIMSIKLNEKPIIEKVFESIPFNEIQLVCQEFPIYYLKNFIQFLSGYFEKNHHLEFQMKWVKLISIYHGKYIKTNSLSMITSLRNLQKTITQTYNDISKVCDDNIFSMEYFKTVLLKELKSQEETNKISKKSQKYKKYLESKKNKEQEEDQFSDDEETVYQNNKKNKNK
The following text describes a protein:
Function:
Enables the bacterium to metabolize sucrose as a sole carbon source.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKYKTILQSNKDELHSLYEIANQDSWKPIYHIHPPFGLMNDPNGVSYYNDEYHVFYQWYPFGPIHGMKHWGHVRSKDLINWERMPVAIIPTESYESHGAYSGSAIVKDGLLHLLYTGNIKKPDDSRDAKQCMASMDSQYTMTKYSNNPVIDIIPDGYTKHVRDPKVWKHNDMYYMLLGAQRENKTGTLLLYKSQDLYNWHFQGEITTNLKEFGFMWECPDYFQLSGKDVLLFSPQGIEKDGENFHNVYNVVYAIGHFDIKNLYFHVDSYYEADKGFDFYAPQTLEDSTSRRLLFAWAGSSEITYPSDDYMWAHCLTLPRELTLEDNILKQKPVSELTKLRTTKKDISGDITAGLNVLSTLDDEDSYELIVTLKTEDAKRFGLSLFHNEEECFPITFNREQGTISIDRGNFYHQFGGEYGFERCKKIDIQDTIELQIFVDKSIVEIFLYDGSTVFTSRVFPRKDMKHHIAIFSDAKLNFTITQYKLKRGIV
The following text describes a protein:
Function:
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
Sequence:
MRDWKRLHATLDAAREGREMTVPEAAFLLGQTDPAARELVRSAADRLRAELVGERVSYVINRNINFSNICVQHCSFCAFRRDAQEAGAYSLDFAHILQKTAEAVASGATEICMQGGLNPAVRGAGGRVLDYYLQLVDAIKAPFPRIHLHAFSPQESFFIAREDRLPIETVLAELRAAGVDSMPGTAAEVLHEPVRRRLCPEKLSTLAWVRTVEAAHRTGLPMTSTMLSGHIETAMHRAIHLGVLRTIQKRTGGFTEFVLLPYVGLAAPRALRARVGRDQPELADALLTQAVARLFFGRSLVNHQPSWVKLGLEGAGEALRWGCNDIGGTLMEEHITSMAGARGGTCQTPEALRAAVFQAERTAYQRDTLYQEVAAESIQPAASLKSAAR
The following text describes a protein:
Function:
Mitochondrial intramembrane protease which plays a critical role in the regulation of mitochondrial function. Essential for mitochondrial development and fusion during spermatogenesis and the development of neurons and muscles. Essential for proteolytic processing of Pink1 and HtrA2 into their mature forms. May also be involved, but not required, for the proteolytic processing of Opa1.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MLMSRALCRSWLPQVARRCHANVNVPILRINSGHPAARSCRQIHSNRKQSSNLKPTTGEPAAAEQNTPVPVNNVIKAVAFTGAFTVGCFAGATILEYENTRSLILEKARQARFGWWQSRSLADRDYWTQIKQDIRRHWDSLTPGDKMFAPILLCNLVAFAMWRVPALKSTMITYFTSNPAAKVVCWPMFLSTFSHYSAMHLFANMYVMHSFANAAAVSLGKEQFLAVYLSAGVFSSLMSVLYKAATSQAGMSLGASGAIMTLLAYVCTQYPDTQLSILFLPALTFSAGAGIKVLMGIDFAGVVMGWKFFDHAAHLGGAMFGIFWATYGAQIWAKRIGLLNYYHDLRRTKQK
The following text describes a protein:
Function:
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MTMPTKSFHRTDRVSAQVRRDLGTIVHAAVRDHGLPSVSVSDVEISRDLAHAKVFVTALQQERSAEAVKGLKEIAGQLRTQLARAMKLRHVPELHFHYDDSVDRGERIDNLLRDLDDIGPEAAPDAQDAEPR
The following text describes a protein:
Function:
Histone demethylase required for G2/M phase cell cycle progression (By similarity). Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator (By similarity). May play a role in the regulation of the circadian clock (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MASVWTDIRAVLPSTVSEFPLDFSEKIDLSVLKCLELSRDQLYSEADCPVSAERAQIIIDYSWEKLNIGTWRDVDKEWRRVYSYGCLFKVLSLCHGNPPQNIIQEAVRTCDMSLLMGAAIMDNILQRLVGILRNKIKTTCPNKAERSEEPFSKKRKHDCKSEPVLNPTKEVPRIHCPSLERFRSDFLDPKKPVIIEGITDLWPAFTQHPWSIDYLRTVAGCRTVPIEVGSKYTDEEWSQKLITVNDFIDRYITGTEEDGVGYLAQHQLFDQVPELKEDIRIPDYCCLGEGDEDDITINAWFGPGGTVSPLHQDPQQNFLAQVVGRKYIRLYSPEDTKSLYPHESQLLHNTSQVEVENPDLVKFPDFSRASYEECVLCPGDVLFIPLQHWYYVRSLELSFSVSFWWS
The following text describes a protein:
Function:
Involved in mitotic DNA repair and meiotic recombination. Functions in the recombinational DNA repair pathway. Essential for interhomolog gene conversion (GC), but may have a less important role in intersister GC than spn-A/Rad51. In the presence of DNA, spn-A/Rad51 enhances the ATPase activity of okr/Rad54.
Sequence:
MTEKWTVYRDPINSTQNRDNKDTNGIASDDTNGDQEKWDSALKYRQAKAFWMRHTGQLNISARNANKNRANASERNEQRPDKNNDAIVIKPTNTSNDRKSLKRRPDALPDPPIEKRHKQTTVDSDDDVMIIERTPEKTNSFETPDSIDDDNMSDDMRCRNTFPYIPESRTTVTRMVRSEDGKESRKPCNEHLTTKWLQTQMDHNRGGIVIDENVLNKPRKAWQGASFLSSIFESFRKFKNSAGLSSALIVCPEAKLSEWMLAIRHQFDYARIFVLHKASTTGHETDYVEKIFQDLKETKKIPFGAVLLTTFAEFGKHEKAIVDHQWQLVYLDQGLFEMTRQMRNQIEGMKKLKTPNRFIFTDTSVRDRLEELWWNVDFVFPGRLSDYKTFQTNFQNVIEIGCRLDATPEEASTAYECIVALHVALKPLILSRLIKNPNDWFCRREISKKEVEHIKDIICPLSKRQRRCLKIYKRSDEVQGILRQSSAACVGLKKLTDICDHPGIHKGVTPETKKFGSIEDSGKVRIVFQLLDMWLGTPGAKVVIFTQRRQVAVMLEHFMKQKRIAYCSFLKAKNAYDRENVVNYFENTTDVQILLAPSIMFKLGMQLKKANKVIIFDPEWNPDSDVKHTREMSFLTKKVEDVTVVRLVSEGTVEDSSYFKKLWESGLASRLLSDPKFEPFVPRTTLEEFLTVRPKIKAGKNDMPVVKSHMKNRLLEYEDKQLLSSIIDTTRLDTIRTHFTSFQYHSTTSDRIKSRDVVNRAVRSIIQIDSRLARYWRQMYHQIVDEPTLDPPNPEFYVEPMQIDPYWEAVHPMVPRTSDREELNFLVAMAVDVRSHMLKCYGETEKKLRELFVRNADRSNPIRMFFIYDIFWTFAKFHENWQLWIIRPEYENQSSIRHSLRYDFSFQPDREPRRVGAGSYED
The following text describes a protein:
Function:
Putative cation exchanger.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSQPADINQSESSAETITQGRRADRPEETPSSSVYEQNLRFGDFLMPTVGDADATDSLSQSTNDRDIYSPREIDQYTRKVSSRTDPSTSTISNARQHPRNSVSRLSRSSSNVRQQRDIPKQNFKVRPLSPLRGQSPASLRSEESFTLKERQNAINKTRAFGMRLWKPALYKKFRSINRDADIDIHDEPLKRPNTSISNVIWLICFGAPLFLVIFICYIFFTVLSFFNVPDAIVYSKLCRGLMFYLLYPFGQHVRHKVKRLSVRSPAHPIYQTQHSHYDETPTSHHPDPARLNFLSFSFCVNPMNQSLDCNTTPHRRNASSIIYTLMYYLIIAPTLLITSAICMFTIFFVPCARTLWAICRHLRTCPLSLSFRPNLALPLSMDSSDVVLLCVKKAASWKYYKYTIDGIYIIYFDMLALIIPTIFFGFFGSQGHWFTSSVFLFTASLVSIIPLAYFIGMAVASISAQSSMGMGAFINAFFGSVIEVFLYSVALRKGNAGLVEGSVIGSILAGLLLMPGLSMCAGAIRKKFQFFNIKSAGATSTMLLFAVLGAFAPTMLFRIYGPFRLDCEPCGANCQKCTKHYVLENDSLYKNRVLPFTYCCSIMLVLAYAIGLWFTLRTHASHIWQNFTADDISFLKAEEEVGEPVNQDTAGNMSDSSEGGEAVVNGNSQHHHNRDDASSGLSSNGSENESLEHEPTNELPQRPLVNQSQNSHGDDAPNWSRSKSAIILLSATFLYSLIAEILVEHVDTVLDKFAISEKFLGLTLFALVPNTTEFMNAISFALNENIALSMEIGSAYALQVCLLQIPCLMGYSLFQYYRSGDSISFKHLFTMVFPTWDMICVMICVFLLTYVHSEGKSNYFKGSILVLAYLVSMLGFTFFNY
The following text describes a protein:
Function:
Receptor for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. In terms of antagonist responses, would be classed with the D1-like dopamine receptor group.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLAYGSDPNAEDLYITMTPSVSTENDTTVWATEEPAAIVWRHPLLAIALFSICLLTVAGNCLVVIAVCTKKYLRNPTGYLIISLAIADLIVGVIVMPMNSLFEIANHTWLFGLMMCDVFHAMDILASTASIWNLCVISLDRYMAGQDPIGYRDKVSKRRILMAILSVWVLSAILSFPGIIWWRTSSPHLYEDQSQCLFTDSKMYVSFSSLVSFYIPLFLILFAYGKVYIIATRHSKGMRMGIKTVSIKKRNGKKSNTETESILSSENEPTLRIHFGRGKQSSSSLRNSRFHARESTRLLLKQVSCKSLNDRGEHNNNNTVRQPLLRGTEGCHSDSISRSSQRNFRGRNVTIGSNCSSTLLQVDQPDRMSLSSNSQMVMTSPLSTRRKLNVREKSRQMMRYVHEQRAARTLSIVVGAFILCWTPFFVFTPLTAFCESCFSNKETIFTFVTWAGHLNSMLNPLIYSRFSRDFRRAFKQILTCQRQQKVKTAFKTPLSLVFTQLISVTQMWEQPPNTSIE
The following text describes a protein:
Function:
Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2. Not involved in glycosylation of erythropoietin (EPO). It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Protein modification by this enzyme might be important for cytokinesis and tube formation during embryogenesis. Together with Pgant3, regulates integrin levels and activity-dependent integrin signaling at the synapse in neurons and muscles.
Miscellaneous:
MISCELLANEOUS: The human ortholog GALNT11 (AC Q8NCW6) is not able to rescue lethality caused by the SF32 mutation.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Domain:
There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding; The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
Sequence:
MMQIKRLLCKSCGLGTLLVAVVWLLALLFYSHSLRSSIRSAGWRIDEGNATPRAELSYQARVTVGCTPNASITTGESPAAPKPPSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEYTPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPGEESKKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQLWYETEKAEIVLDKLLCLEASGDAQVTVNKCHEMLGDQQWRHTRNANSPVYNMAKGTCLRAAAPTTGALISLDLCSKSNGAGGSWDIVQLKKPTEAEGRAKEARNSDKAL
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Cytoplasm. Mitochondrion.
Sequence:
MQSRFLISPTLIRTFAHHANLTPRKILHDLPEAAHARKQIPLRPGVILVKKGMTNAWDEKTGMQVPLTILQFDRVQAIDVRTKEKHGYYAVQVGSGIRKPKSITKAEQGNFFSHNIYPKMHVREFRVRDASGLVSPGTIFTTDYFKPKQYVDVKGITKGKGFAGVMKRWGFSGGNASHGASLSHRTPGSTGQNTTPSRVLPGRKMAGHMGHRSRTVKNLLVWAVDADLECILVKGSIPGPNKSAVYVTDTINRSTSATN
The following text describes a protein:
Function:
Involved in formation and maintenance of cell shape.
Sequence:
MLAVLSVSLMVVDARFDYLEPVRSKLGMVLTPFYGLAEMPVRAWEGVRDQFSSRSELIAENERLKAESLLMQRRVQKLAALTEQNVRLRELLNSAALVDDKVLVSELIGVDPNPFTQRIMIDKGENDGVFVGQPVLDASGLMGQVVEVMPYTARVLLLTDTTHSIPVQVNRNGLRAIAVGTGNPERLELRYVADTADIKEGDLLVSSGLGQRFPAGYPVATVKEVIHDSGQPFAVVRAVPTAKMNRSRYVLLVFSDSRTPEQRANDAAEAQEEADKKAAAGAQAPQPAAQPAAAPSPATPAAQGAAQQPAAAPAPAPTQPAAPAANGGRR
The following text describes a protein:
Function:
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity). Required for division ring constriction.
Subcellular Localization:
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Sequence:
MQDIVREAMERDEAERQTQSSLEDSDDQFGDPRIVIVGAGGAGNNTINRLYNIGVEGADTVAINTDKQHLKMIEADTKILVGKSLTQGLGAGGDPSMGERATEMAQGTIKDVLGDADLVFVTAGMGGGTGTGAAPVVAKIAKEQGAIVVGMVSTPFNVERARTVKAEEGLENLRNEADSIIVLDNNRLLDYVPNLPIGKAFSVMDQIIAETVKGISETITQPSLINLDYADMSTIMNQGGVAVMLVGETQDKNKTQEVVNDAMNHPLLDVDYRGASGGLVHITGGPDLTLKEAEGIASNITERLEAAANVIWGARIQDEYKGKVRVMAIMTGVQSAQVLGPSTQKQADKSRQSIQSRESQQQHSGSEFDSSERAQTAQSGTWSDGGRDEVEKNNGLDVIR
The following text describes a protein:
Function:
Essential component of the RNA polymerase transcription and replication complex. Acts as a scaffold which brings L in close proximity to the N-RNA complex. Plays a role in the segregation of the viral genome in host daughter cells during mitosis by interacting with host HMGB1, a host chromatin-remodeling DNA architectural protein, thereby stabilizing RNP on chromosomes. Interacts with host TBK1 and thus interferes with activation of cellular antiviral state. Inhibits cellular histone acetyltransferase activities.
Miscellaneous:
MISCELLANEOUS: The P/X gene has two overlapping open reading frames. One encodes the P protein and the other the X protein. The P (p24), X and P'(p16) proteins are produced by ribosomal leaky scanning.
Subcellular Localization:
Host nucleus. Host cytoplasm. Note=P subcellular localization is modulated by the interaction with protein X.
Sequence:
MATRPSSLVDSLEDEEDPQTLRRERPGSPRPRKVPRNALTQPVDQLLKDLRKNPSMISDPDQRTGREQLSNDELIKKLVTELAENSMIEAEEVRGTLGDISARIEAGFESLSALQVETIQTAQRCDHSDSIRILGENIKILDRSMKTMMETMKLMMEKVDLLYASTAVGTSAPMLPSHPAPPRIYPQLPSAPTTDEWDIIP
The following text describes a protein:
Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MFLSMRAEEAMFRSADMTYIELYIPLEIAREVVCVLGNLGSVMLKDMNKDLSTFQRGYVNQVRRFDEVERQVGYMEGVVRRHKNETWRYLYRHLQREEQQEYPGREHPTLAQLIGSMHTHSIDSVDEVAEEIMQFEGRVRQLDQSLVAMRERLSKLVHERRVMFTCEHFLEVNPGIGERLPTRPAGFEADEFELTRVGEEDEETASQLSFDISDDAETQLPGDMRTLLEPVYRHQYLLTGSIERAKVEALNKILWRLLRGNVFFQNFPVSVSPVEEDDTDLETDCFIVFTHGEVLLSKAKKVIESLNGTIYPFMQDGATVQELNDKIADLKQICSTTEQTLHTELFLVANQLPMWNAIIKREKYIYSALNLFRQESQGLVAEGWLPTYDLPGVQAALKDYGESVGSANSAVLNVISTTRTPPTFHRTNKFTQAFQSIVDAYGIATYKEVNPGLATIVTFPFMFAVMFGDAGHGALMLIAALYLVLNEKKLGAMKRGEIFDMAYTGRYVILLMGIFSIYTGIMYNDIFSKSMHLFSTGWKWPSNFQEGEMIEAQKVGVYPFGLDYAWHGSDNSLLFTNSYKMKLSILLGFIHMSYSYIFSYLNYHYKGSRIDIVGNFIPGLIFMQSIFGYLSWAIIYKWSKDWIKDELPAPGLLNMLINMFLSPGVVDEKLYTGQSFLQVILLLAALVCVPWLLLYKPLMLKRQNDIALSKGFRSLRDQRVHEILLEAQENAGEDMLVADYENEDESSEEFNFGDVMIHQVIHTIEFCLNCISHTASYLRLWALSLAHAQLSTVLWSMTIQNSFSDSNPGSFFSVTKVVVLFAMWFVLTVCILVLMEGTSAMLHSLRLHWVEAMSKFFEGEGYAYEPFSFKAINSDDE