lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Regulatory protein of the TOL plasmid xyl operons. XylS activates the xylXYZLTEGFJQKIH operon required for the degradation of toluene, m-xylene and p-xylene.
Subcellular Localization:
Cytoplasm.
Sequence:
MAANRLLARPWLPGVELFHADFSGQAFGRHSHSAFAIGSILHGVGGYQCRGRRHALPAGTLSLMNPEEPHTGHAESERLVYRMLYVEETRLLGLLGRKQLPRGFGELNPADDGSVAAGLAWLAEDFQRSDALGLESRLLALLEQVFVRHGGLRPAAAAPRDGGTTARLRDYLEAHATEALGLDQLAQLLQRHPRHLIEAFRRAYGVPPHTYQLQCRVRQAKRLLLEERPLAELAQHLGFYDQAHFSTTFRRFTGVTPGQFRRSAKT
The following text describes a protein:
Function:
Catalyzes the phosphorylation of (R)-mevalonate 5-phosphate (MVAP) to (R)-mevalonate 5-diphosphate (MVAPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
Sequence:
MIKVSAPGKILWIGSYSVVFGGISHVIAVNKRVSCSLREIKEKDSLIFHTSYGHFKNSGNELINSVLDTFRERLSQLPQGYEIDLYNDKEFIIDGKKTGLGSSSAATVSLTACLYYAIHGKLDLFEIHKLAQIANYKRQKGIGSGFDIASAVFGSIVYKRFTDLDKMDFYFEKLNLGNYDMMLGFTGKSSETVGLVRKFVEKSNLDDFKEIMRLIDEENYMAIKLIKLNKLDEAVEHIKLGRKYLNYIAERIVGVKLVSKMEEELIKIAEEEGALVALSPGAGGGDSIFALGNDLNRVREAWSKRGIFIIDVKEDEGLRLESN
The following text describes a protein:
Function:
Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
Subcellular Localization:
Endoplasmic reticulum membrane. Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein.
Sequence:
METLYQQTNRLILEVQSQLNKLGFAKGDELTELERHIDAILGEISSNCDKLNILVNKEPAIKRQGAKIKADQLVYDLRHLQTAFHNYQQRRIQREEEERERDELLNKRFLPNNSGETSVMIDHALQHNTGLQNAHQGMDEMISSGSSILTSLREQRNVLKGAQKRILDIANTLGLSNTVMRLIDKRGTQDKWIAFGGMLVTCIIMFLVIHYLT
The following text describes a protein:
Function:
Adenine glycosylase active on G-A mispairs.
Sequence:
MAVSTKRRAASSSRDDYSPCASPPPSAHRPIKKAHRSLGDSESSVFKIAAILDAPSSSRHARAPARLPARMHSASYHRPQLLDHPDAIIALLTWFETVSSKRDMPWRADFIDASHYSDAAKLREARKKRAYQVWISEIMLQQTRVETVKTYWLNWMNKWPTIEALAAADPEAVLAAWRGLGYYSRATRIHTAAKRVVADPHMMGLLPETPQELEKNVPGVGPYTAGAISSIVFGQAVPIIDGNVVRVLSRQLALYANPKTKLTSHLMWATATKLVHKASALRGGKATVPGQWNQALMELGSTVCTPTKPRCDECPIQATCSAHQEAQADTIKANNKPNQAAGAEVLDIEDICTLCERFPSVQVDSISTTETHQDTNVAKQKSINNLRQATLSFGLRSASKRKRASSREPSALTTIDIERHICKFPMKLEKKTIRQEECLVCIIQRSSGEFLLEQRPASGLLASTWQFPSLTLSTTAAGSPSDQRQPVFGSKPTAKLVDPFTASLIDAKNTVESQTNLGSITHIFSHLHLTMHVYSIALRPDSAVREISNQQETSTTMTTTTTTADKNKNFGSRLGDMATRRWANVDQVEAETMGTGMRNCWLALQSQNKLLSTKTRTSK
The following text describes a protein:
Function:
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners.
Subcellular Localization:
Secreted.
Sequence:
MQPRMLLIVALVALLASARADEGEGSLLLGSMQGYMEQASKTVQDALSSMQESDIAVVASRGWMDNRFKSLKGYWSKFTDKFTGLWESGPEDQLTTPTLEP
The following text describes a protein:
Function:
Required for ciliogenesis.
Subcellular Localization:
Cell projection, cilium. Vacuole membrane; Multi-pass membrane protein.
Sequence:
MLQTSNYSLVLSLQLVLLLYDLLVNAFSELLRSAPVVQLVLFIIQDIAILFNVIIIFLMFFNTFVFQAGLINLLFRKFKGTIILTAFYLSLSIPLHVWVLNLRWTDSKHYVWTDGLQTLFVFQRLAAVLYCYFYKRTAIRLGDPRFYQDSLWLRKEFTQVRS
The following text describes a protein:
Function:
Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MGSPGASLGIKKALQSEQATALPASAPAVSQPTAPAPSCLPKAGQVIPTLLREAPFSSVIAPTLLCGFLFLAWVAAEVPEESSRMAGSGARSEEGRRQHAFVPEPFDGANVVPNLWLHSFEVINDLNHWDHITKLRFLKESLRGEALGVYNRLSPQDQGDYGTVKEALLKAFGVPGAAPSHLPKEIVFANSMGKGYYLKGKIGKVPVRFLVDSGAQVSVVHPNLWEEVTDGDLDTLQPFENVVKVANGAEMKILGVWDTAVSLGKLKLKAQFLVANASAEEAIIGTDVLQDHNAILDFEHRTCTLKGKKFRLLPVGGSLEDEFDLELIEEDPSSEEGRQELSH
The following text describes a protein:
Function:
Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Shows a greater preference for D-erythro isomer of ceramides. Binds phosphoinositides.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm.
Sequence:
MGAMGAAEPLQSVLWVKQQRCAVSLEPARALLRWWRSPEPGPSAPDPDAYSVPVSEIIAVEEKEVHQKQSSNGRWHRMENPFAFTVHCVKRARHHRWKWARVTFWSADEQLCQLWLQTLRELLENLTSRPKHLLVFINPFGGKGQGKHIYEKKVAPLFTLASITTEIIITEHANQAKETLYEINTDSYDGIVCVGGDGMFSEVLHGVIGKTQQSAGVDPNHPRAVLVPSTLRIGIIPAGSTDCVCYSTVGTNDAETSALHIIIGDSLAIDVSSVHHNSTLLRYSVSLLGYGFYGDLIKDSEKKRWMGLVRYDFSGLKAFLSHQYYEGTVSFLPAQHTVGSPRDQKPCRAGCSVCRQSKRQLEEEQKKALYGLENAEEVEEWQVVCGKFLAINSTNMSCACPRSPGGLSPFAHLGDGSSDLILIRKCSRFNFLRFLIRHTNQEDQFGFTFVEVYRVKKFQFTSKHVEDDDNDLKELEKQKFGQICKDNPPCACPTSRSSWNCDGEVLHSPAIEVRVHCQLVRLFARGIEEES
The following text describes a protein:
Function:
Probable methyltransferase required to silence rDNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTNTKKSKQKNTVGNKVKKTNTNKNNNNNNNNNNKNKQNKINNKNNKNNKNNDSNNKNNNTNNKNNINIKNKNLKKVENNKSLKVISSNKNKNILNNLKKEEKVNSNDILIQQQQNREKEDITNEDDDEKYNLWNPKPTSSVSVSSSKSSKSLKTTDLQNEMSEKLKGSRFRWLNETLYTTHSKEAFKEFSEDRSLFDQYHSGFKSQVESWPINPLDLIIDDLSSIKQRKRIADLGCGEAKLAERLQHKHTIQSFDLVAVNERVTACDISNLPLKNESIDIAVFCLSLMGTNFIDFIIEAERVLVKGGLLKIAEIESRITDINAFTNEIQQHGFNLIKKNEQNQYFTLFEFSKLQKKDQQFMRSLKQYQKLKKQQATNEPVLKPCLYKKR
The following text describes a protein:
Function:
Essential for recycling GMP and indirectly, cGMP.
Subcellular Localization:
Cytoplasm.
Sequence:
MNDPSCSSADETAHPGRLVIISGPSGAGKSTVVKQLMKRCDVPLQLSVSATTREPRPGEIHGQDYFFLSHEEFERRRKLNDFVECKQVFSMGQWYGTLKDQVATGLNAGKWVILEIDVQGAMAVLDDPHYRPVTIFVHPGSMEELERRLRNRGTESESSLTARLETAAAEMQCLSRYQYEIINESVDNAVTEICQILLDQRKTTPCSKN
The following text describes a protein:
Function:
Probable E3 ubiquitin-protein ligase that may regulate the response to iron deficiency and thus contributes to iron homeostasis.
Subcellular Localization:
Membrane; Single-pass membrane protein. Nucleus.
Sequence:
MGGGNLHSLPPENASVSASYAVTVGNTKLSDAPVLFFVYCHKAFRAQLVELRRFATDAAEADSFSGDLAVELSRKFEFLKLVYKYHSAAEDEVIFLALDKRVKNIVSNYSLEHAGTDDLFTSIFHWLHVLEEEIGSRSDVLREVILCIGTIQSSICQHMLKEERQVFPLLIEKFSFREQASLVWQFICSVPVMVLEDFLPWMISHLSHEEKIEVENCIKDVAPNEDSLQQVISSWLLDDSQSSCGTPTEIMKGVQYVNVSKSLKKSPESHPSSGCFQRFWEWSKKSLSIPNVGRSPIHGLRLFQNAIEKDLRDIQEGLCQAKFQTLILDLDVLMARLNFLADVLVSYSNAFKKFFHPVLEEMTARRSSTAKQFNIDDCLENFQRLLYKSADDKTKTDNFLLQLQEELESLIIQVTKQFAIQRTEVFPIISKNCNHEMQKQLLYTSIHVLPLGLLKCVILWFSAHLSEEESQSILHFLSLEDSSPKKSFPRLLLQWLRFGYSGKTSVERFWKQLDVMFKVRCSCQKEHTEEASGSFSNQTQLQLCKVSKDVYPRKKDKSSTCFMSMDLAVGDMYETPYSSRMNQQMTFSGKLKPPLHLPDFFGEKNMDDPMIMDVKPIDLLFFFHKAMKMDLDYLVCGSTRLAADFRFLAEFQQRFHMIKFLYQIHSDAEDEIAFPALEAKGQLKNISHSFSIDHELETKHFDKVSFILNEMSELNMLVSTINTTAADHDRKMKYERLCLSLREICKSMHKLLSEHIQHEETELWGLFRNCFSIEEQEKIIGCMLGRISGEILQDMIPWLMESLTSDEQLAAMSLWRQATRKTMFVEWLTEWYNGHVLQEEAGEANNDPFGDSDPLEIVWKYLFEASADGEKGSMRSSLLKLPKTNFTGIMNQPPPNYKVEVGKKEEKDLERSESKKICRGSNQEGDKEQTDKMSQKVSQFGPSKKYEQLLTMSEEELVVVIKKISCDSSLDPQKKDYIKQNLLMSRWNISQRTYNLEPSSLSSNMETVHGQHPSYRDPHSLIFGCNHYKRNCKLLAPCCDKLFTCIRCHDEEADHSVDRKQITKMMCMKCLLIQPIGANCSNTSCKSSMGKYFCKICKLYDDERKIYHCPYCNLCRVGKGLGIDYFHCMKCNACMSRTLVEHVCREKCLEDNCPICHEYIFTSSSPVKALPCGHLMHSTCFQEYTCSHYTCPVCSKSLGDMQVYFKMLDALLAEEKMPDEYSNKTQVILCNDCGRKGNAPYHWLYHKCTTCGSYNSRLL
The following text describes a protein:
Function:
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Sequence:
MDPFGDDAPVEGEVPAEISDFAPPADNANDFYEVEPTEAAATETYEEHTEEGYQESYQPMEFAQEQPAETPADFSADVPAPVDIPAQIPVVEEDNELTKFMREYEEKIALKAQEQEKVAVECKVKAEDDMSQFVTERQRIKESKMQANRVFEQATLEKMVADLQNENPWERVVTLVDLETNRKKKLDALNNNKKEAKQDQKPVAVPAKKTPEDEEDVSRMRQLFVQLKTTPLEQTRADAVAAN
The following text describes a protein:
Function:
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MANPQEHLSGSSSPHLPLSENKTFNGLQDDITPMGSQPSPKLLKDQQEKGVVQTELPEGMNSPITTTVLTSISEDSRDQFENSVLQLREQDESEMAVSHRNSNTMDGEGTSGTEDIKIQFSRSGSGSGGFLEGLFGCLRPVWNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVAIKKVREQNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLDIASADVLATPQETYFKSQAEWREEVKKHFEKIKSEGTCIHRLDEELIRRRREELRHALDIREHYERKLERANNLYMELSAIMLQLEMREKELIKREQAVEKKYPGTYKRHPVRPIIHPNAMEKLMKRKGVPHRPGMQAKRPDLLRSEGIPSVEVAPTASPLSGSPKMSTSSSKGRYRSKPRHRRGNSRGSHNDFAAILKNQPARENSPHPTYLHQAQSQYPSPHHPNPLQQQYQQPPPATSQSHHPRLNMHGQDIATCANNLRYFGPAAALRSPLSNHAQRQMPGSSPDLISTAMAADCWRSSEPDKGQAGPWGCCQADPYDPCLQCRPEQQRGSLDLPSAEPGGRSPNLFKSPAHNPLSESAQASEKMEENEFSSCRSASPLGTSHHITPPVLPRKTRPLQKSGDDSSEEEEGEVDSEVEFPRRQRPHRCISSCQSYSTFSSENFSVSDGEEGNTSDHSNSPDELADKLEDCLAEKLDDLLSQTPEIPIEISSHSDGLSDKECAVRRVKTQMSLGKLCSEERGYENPMQFEESDCDSSDGECSDATVRTNQHYSSATW
The following text describes a protein:
Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Sequence:
MVSSCCGSVCSEEGCGQSCCQPSCCQTTCCRPSCCVSSCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCCISSCCRPSCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCCRPCCGSSSCCGSSCCRPSCCTSSCCRPICCQATCSRPGCCVSSCCRPQCCISSCCRPICCQTTCCRTTCCRPACSSGSCC
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
Sequence:
MAGRGKLIAVIGDEDTVTGFLLGGIGELNKNRHPNFLVVEKDTTINEIEDTFRSLGSVSGSVAEANPSQHDPPLWDEIDSWQFLNRDDIGIILINQYIAEMVRHALDAHQHSIPAVLEIPSKEHPYDAAKDSILRRARGMFTAEDLR
The following text describes a protein:
Function:
Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAWQARQKLKWALLALLGMLGAAARFGLQRVADESGFAALASLVPLMLGCFILGASTRFFAGRPVHNELALGVGTGFCGSLTTFSSWMASAAQRLVDAQHTLSTGDQIYGYFVIIFTGLLASFGGFAMGRRLLFCNSTSRLGTFYANMLGTLVVAVLLAVLLRGDFGNEDGWERGTTVIYGLITGFAGCLTTVSTFVKELNEKDSVARALKAPAWSRWTLQPWRYALGSIVGSQIILLGVYGSFGWTN
The following text describes a protein:
Function:
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
Sequence:
MGTVNITVSDGVRYAVADEGPNASEAVVCLHGFTGSKQSWTFLDEMLPDSRLIKIDCLGHGETDAPLNGKRYSTTRQVSDLAEIFDQLKLHKVKLIGYSMGGRLAYSFAMTYPERVSALVLESTTPGLKTLGERRERIMRDRKLADFILRDGLEAFVAYWENIPLFSSQQRLAEDIRYRIRSGRLRNNKIGLANSLTGMGTGSQPSLWSRVEEIDVPVLLICGEWDEKFCAINQEVHKMLPSSRIEIVPKAGHTVHVEQPRLFGKIVSEFLTSI
The following text describes a protein:
Function:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
Subcellular Localization:
Nucleus.
Sequence:
MSSGQQLPEDDDEFQEFREADWTEDKEDHEDKDLWLEDWDNEDFDDDFTKQLRAELLKIPPTGVALDTSASGAGSK
The following text describes a protein:
Function:
Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MWLFFCNGKRKQVMTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRKMKRAGLDYWDKLEIYFYESLEDFMSQMKGKLYLISKFAEKVYSDVDLSTNEDHYFLFGREDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHTYEVDKLK
The following text describes a protein:
Function:
Transcriptional activator.
Subcellular Localization:
Nucleus.
Sequence:
MADSKHQVIFCNDSPKRVLVSVIKTTPIKPRTTADSLMPTSPGFSDFMVYPWRWGENAHNVTLGPGSGSGAASPTRTSSSPAEADPLSCPEHLKDGIRRGRPRADTVRELINEGENSTSRIRCNICNRVFPREKSLQAHKRTHTGERPYLCDYPDCGKAFVQSGQLKTHQRLHTGEKPFVCSEKACGSRFTHANRHCAKHPYARLKREEPTGGPGKSQGADNKAVAEWLTKYWQTREQRSPVPGKAKPQNKSPLEDQEQQDPLDFLPSDEGEEEEQEEEKNAPSGGVVTARRRLQEQRERLHGALALIELANNLSA
The following text describes a protein:
Function:
Recruits the lipid transfer protein VPS13A from lipid droplets to the endoplasmic reticulum (ER) membrane.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MKFPASVLASVFLFVAETMAALYLSSTYRSAGDRMWQALTLFFSLMPCTLVQLTLLFVHRDLSRDRPLVLLMHLLQLGPLYRCCEVFCIYCQSDQNEEPYVSITKKRQMPKDGLSEEVEKEVGQSEGKLFTHRSAFSRASVIQAFLGSAPQLTLQLYITVLEQNITTGRFIMVLSLLSIVYGALRCNILAIKIKYDEYEVKVKPLAYVCIFLWRSFEIATRVIVLVLFTSVLKIWVVVVILVNFFSFFLYPWILFWNSGSPFPENIEKALTRVGTTIVLGFLTLLYAGINMFCWSAVQLKIDNPELISKSQNWYRLLIYYMMRFVENSVLLLLWFFFKTDIYMYVCAPLLILQLLIGYCTSILFMLVFYQFFHPCKKLFSSSVSESFSACLRCVCWSSARRKSTEPVGRIDTDLKACTDQGAQPSTSKLTPEATEIWTAVDLCST
The following text describes a protein:
Function:
Component of the gamma tubule complex that is required for the regulation of both interphase microtubules and mitotic bipolar spindles.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=And the microtubule organizing center (MTOC).
Sequence:
MDGIMKNDLLWFGNHVFDLTPNSFDSDFVEQLSKFEGKEGLKRKLFDSSEYFQNFSFQVNDDLLGKDVILDISNQQLTPAVPGCETSSNSKLISASKEITSERKRAKSSVSPSYLTDSSPSDLSVENKVLLTCPSWDGENFKNLEARSPFISEAPSRVYDYFLHNQDWSPKPLFSALQVYPLATIFNCVAGLPQGFESTVFPWNKTSSTFELDPTISVSGMSDECFASIVQKFSAIGGLIKKALNEFSLYKTNISFYLSNFIVNGVLQYRKEFQRWLRLYEFRRFGLIGLSNFVNSFSSFFELISHFLIKSAQNLKGDSLLDFLFDYARSCQNTISYPIALQCLIYCSNPYFKRLELALKVSCAYGHIDSSLFLSLPRFFPSELCVSIEQCIQFLSLIREQKEIFNKNNKEFINPLNIRFAYSFNDINQACVIEERCNFSSLSFGNLEQTSVNNDSEEFETLLAKMNMTPDFNDNLLQLKFTDDVRNVCPLNLNVCCCIAEPIQSFILSFLRSTYKVLKNDFQVFDLLNFFHSTFLFQNYEFSDNVISLLKSRRLDKSDRNELAEDLNSDDRYNFISRLKKFIFMEKEKNGLSRSLSKSITFTLDSASVSEFEDVYPDLQFQCQVIGALRILFTDNSLNYYSKTFSYVLHLFQAQSDFESSVELKDRSIVTKTTIMSWSKYQGTKESLFQFLSIYIPECMLPFTKLLKSIYSPDCPTNIQNSAIKNAASVHEQCTKAIYQKVKELFDTMKLWESSIKVS
The following text describes a protein:
Function:
Non-essential protein which is required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MNSTAAAINPNPNVIPFDDTYILYDSHDFLSFLSAYFSLMPILVLAFYLSWFIITRELEACIVAFGQLMNEIFNNVIKNIIKQPRPVSFGASFQNDTIRSGYGMPSAHSQFMGFCFTYNSLKIYTSWKNLNFLEKCIFSGALALLSFCVCFSRVYLHYHNLDQVIVGFSVGALTGSLYFFIVGIIRELGLINWFLKLRIVRLFYMTDSYNLAPLTLKENYEAYWKRINQRSFNDKSKRD
The following text describes a protein:
Function:
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Subcellular Localization:
Nucleus.
Sequence:
MSHITPSRRKEERYIPFNNDPRNIGTRTGLPMPQNVPRDSNGFEIPALFFGSSPENGANRTISSIKSKVAQTPGGRSTYSRADSTPGTARRLTRRLSDLDMDDGLRGGDDLLMDEDDLAIATPGSLFANSEPPPSIILPSRSRLPISSPANASFDSVPSPSVRPSPRKSHYSAASRVSSSLAKTVTKVHELSGDEEEPFLTPGDGLNQEGEPEESPVKSKKKTPRAASSDDDGSPAKDKEAAFPPEGRSASMSGNKPANDYDAGYEGNHTVDFDDLPPMGPIDDYDVETVLRTEREEDDEDAQNVDNNVVEEERTMEEEEMQVSESEDGEERRPVVAKRKKSPKKQEKGKDRARSARSGSTAAQRKRTRPSELGPGDDGYHGNFVTRRSGRQHYKPLEFWRGEKVEYMRGPGCAVIKEIITIPEDPPVPLALRKSRKNGRARSGSVAVGKRKREDSVEDEEGWDHKTEPTGLVQDYPFGEECYRKIACPKALLDPKLVSGGNFKYQKVFGEGHFMAAGIVYIPVGQIKNTKPSKDNTYVFYVIQGAVQVTIYRTSFVMAPGSQFLVPRGNDYCIENISPDKEAQLFFAQARKIRANEIDADGVSESQAGEAGLPSRKSISASQTQGGKKSNRLPSVREESRDISQSEREDEEEDEEEEEITVKKRRKSKGKSRR
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MPQPFLGIPFANSEMVPISYLGTSNVTYKEMRRSYENEQRPNATIVQEHRITPRATNNPVFRPATENIRSLRNNRSEDTSAIYVLDSTPPYNQEEGNSIVVPPKTIEKRIATLSTSVPTPGMTRSKGIVLSSPENVIPESNYGQKPLKKAKYCDNYGVILMDANYLLKTMPSVTTSINEKQTEGILYSFGKEKQVSIVCLCHGMFFTPAEFVKHNGGNEVDNPMKYIKVITEEKINVVAESLVGFF
The following text describes a protein:
Function:
Component of the GPI transamidase complex. Required for a terminal step of GPI anchor attachment onto proteins. Affects endocytosis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMPSQAYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYENEQYGETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFSENPRAALRSWVEAYHTSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHGLPSDQLTNNNFWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFINNAYANISLFSEYNLVALLVWFVSLVISFVVSQAFLLIPSSGLLMTISMASCFLPLILSRKIHISEPLSYRLKNVAFLYFSLVSTSLLMINFAMALLIGTLAFPMTFVKTIVESSSEHEVTTQSSNPIKTEPKDEIELVENHMDTTPATPQQQKQKLKNLVLLILTNPFISITLFGLFFDDEFHGFDIINKLVSAWLDLKCWSWFVLCIGWLPCWLLILASSFESKSVVVRSKEKQS
The following text describes a protein:
Function:
Translation regulator that binds to the 3'-UTR of specific mRNAs such as nanos (nos) and prevents their translation. Prevents translation of unlocalized nanos in the bulk cytoplasm via the recruitment of cup.
Subcellular Localization:
Cytoplasm. Note=In the cytoplasm of syncytial embryos, accumulates in discrete foci.
Domain:
The SAM domain mediates the association with the 3'-UTR of specific mRNAs.
Sequence:
MKYATGTDNAMTSGISGQTNNSNSASNEMQPTTSTPTAAHKEATSTATTTATYANGNPNSNANPSQSQPSNALFCEQVTTVTNLFEKWNDCERTVVMYALLKRLRYPSLKFLQYSIDSNLTQNLGTSQTNLSSVVIDINANNPVYLQNLLNAYKTFQPCDLLDAMSSSSSDKDSMPCYGSDFQITTSAQCDERKLYARKEDILHEVLNMLPLLKPGNEEAKLIYLTLIPVAVKDTMQQIVPTELVQQIFSYLLIHPAITSEDRRSLNIWLRHLEDHIQAAAAGLTNRSYFLQPSPQLVAGGSSTGSGSCSSSATSSSTASCSSVASSSLCPASGSRSSRTNDWQTIAPPSKQLQNKLAGDWRGNGGGSSSGSINPLCDNLNGITLNELASSQNSLGLSLEGSSSLVNGVVAGAGSMLGIAGGDDHDTSFSKNGTEILDFDPVTADMGEACSLASSSLCGRNGGNPVEDRSQPPPNLQQQLLQPPPYASILMGNVGDQFGEINRWSLDSKIAALKTRRSNSLTTQTISSCSSSSNSSVITVNDNCSNSTENLAQFANKPRSFSLSIEHQRGALMNSGSDTRLDEFKPNYIKFHTRNVGMSGIGLWLKSLRLHKYIELFKNMTYEEMLLITEDFLQSVGVTKGASHKLALCIDKLKERANILNRVEQELLSGQMELSTAVEELTNIVLTPMKPLESPGPPEENIGLRFLKVIDIVTNTLQQDPYAVQDDETLGVLMWILDRSIHNEAFMNHASQLKDLKFKLSKMKISMVPKMHHVKPAGVGPNNGNINKPRWNGKTRKCDTKNGSNDRINNRKNSNDMLNFSLNCLPHPLPHHSQQAPPPLPQFDYNGYGGGPSHQPQYKSSSYPSFMGNPQQQPPPPPSSKSHHHPQQMQQMLQQHNHFPALPQQTPPQSHRRSLNNLILVAGGPQQPQQLIFKPGQGVLTNNGSNDNLVLERNQQSQQQQQQRKLSGGVSSAEQQPKKTMAAVVMENLAKFDQHFTLF
The following text describes a protein:
Function:
Class I alpha-mannosidase essential for early N-glycan processing. Progressively trims alpha-1,2-linked mannose residues. Produces Man(5)GlcNAc(2) from Man(8)GlcNAc(2), but only Man(6)GlcNAc(2) from Man(9)GlcNAc(2). Has difficulty acting on the terminal mannose of the b-branch. Involved in root development and cell wall biosynthesis.
Subcellular Localization:
Endomembrane system; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass membrane protein.
Sequence:
MARARSSSLQVWRFINPSYYLKRPKRLAILFIVFVLTSFAVWDRQTLVREHYVENSELRNELHQLKDQLDDVKNYLGDKANDIFEKSREALGTSIQDDDDPIDVERREKVKEAMLHAWNSYVKYAWGQDELQPQSKNGVNSFGGLGATLVDSLDTLYIMGLDEQFQKARDWVATSMDFNKNYVASVFETTIRVVGGLLSAYDLSGDKIFLEKAQDIGNRLLPAWNTPTGIPYNQINLANGNAHNFGWTGGDSVLADSGTEQLEFIALSQRTGDPKYQQKVENVITQLRKTFPSDGLLSIYINPNSGQSTRSQITFGAMGDSFYEYLLKVWVQGNKTESVKLYREMWETSMNGLLSLVKKTTPSSFTYICEKNGEYLSDKMDELACFAPGMLALGSTGYGPDKAKKILSLAEELAWTCYNFYQITPTKLAGENYFFNSGQDMSVGTSWNILRPETIESLMYLYRMTGNKTYQEWGWNIFQAFEKNSRIESGYVGLKDVRSGEKDNMMQSFFLAETFKYLYLLFSPPSLISLDEWVFNTEAHPLRIVQRNGGKSEIVKPNAMILGRKQGRNGLK
The following text describes a protein:
Function:
May regulate cell survival and anterior-posterior patterning.
Subcellular Localization:
Nucleus.
Sequence:
MAKAVGSAGILVKESALLLHPELLSRDFLLLSLERRNIPVEDALNNKEKLTEIFVQHAMPLPQRDLPRNRWGRMMESKRGENKIATVLKSAGTEGGRKRPPIVFDGCSTSTTIKVKRTENGDASQRLNPSPKESTNSTQNSNPAPRLGSPTPNKEAKVATTGNHGQLDSLPVTDSALVSPKSAKLQQSMIINAVKLKRNAPKEEFDVANDTKPTEAKKKIQHVTWP
The following text describes a protein:
Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Sequence:
MGVSDSDFDDRIRFFRTKAPSALNPVFASQTRKKAAFTEESNLFVDSECNGCIQMTELDFYLDLILSRYSYGHYTMLNGATIMDGALLLNVANESCPQPQTSEHLAAVEIMCLQHIIILQNKVDLIQENVAINQHEGTIADNAPVVPISAQLKYNIDVVCEYIVKKIPFPERNFISPPNMIVIRSFDVNKPGFEVNEIRGCLENEPIYRGGLIGVGTTMDPTLTRADRLVGQVLGEVGSLPEVFVELEMMFPRKLSKGARVIAVRNDLAKLQLTSPVCTSRGIAFSRRVEKHCRLIGPYAWSKAIGTVVAGGDLVASVGDPSRPEQTKKTSLWKKFHRHMYMAANICRTSLDEHYLCRQKFF
The following text describes a protein:
Function:
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
Miscellaneous:
MISCELLANEOUS: The reaction proceeds by a bi uni uni bi ping pong mechanism.
Subcellular Localization:
Cytoplasm.
Sequence:
MIVCKTPEEVLDQVRLWKAQGKRIGFVPTMGYLHEGHASLFEECISKADKTVVSIFVNPAQFNDPEDYAKYPVNTEGDLKLCESKKVDLVFLPNKETIYPDGIPDIVLKIPNLMKSLCAVSRPGHFEGVLLVIFRLFHFVQPDFAFFGKKDYQQYLLIREFCNTLAFPIEVIGCETVRSSQGLALSSRNSRLSETEKEESLLIYRSLKLGENQIFSGIKNPLLVKEIMKDVLDSSSKIRLDYLEILNADTLDPLEVLEGEILLAIAAFIGPVRLIDNLTLSVPTS
The following text describes a protein:
Function:
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
Subcellular Localization:
Nucleus.
Sequence:
MPKVSARFRNRKINFRTRITIHTGPLDTPSDHEEDDYPFEDDRRQSIGGPATDRSHIVETGVDKEEESELHLQKVINASTAALMRSAVNQRKPASPGLIAELADTAAHSTLATQSSTTINSNNNTAPNDSNVPHIPIPDAAGLVDPATYEALYAHSKIFLPSSYIRFSDTVEDTLGGVVYTMDEEDEAWLNRFNSENNAPHSDHNHKGGSTPDENGKNRRTNSRKGKEKERSVTETDGPGHLAEDDFEAIMDHFEKTTEETVPGLHLDTNRLPSLADLEPSLESPLISQRLSSVKIFAKFVYSHWKERRLKRGGKPIMPAVDFDETNESNPYVCFRRREIKMVRKTRRTDTQNMDRLVRLRNDLYKAQELLNTVLARERTKREAVELEKAIFEGRCLIREMKRSLNEADGDEELLVSKKEKRRKREQSGNGTLKSPLRNAAGPSLSGTGSAGASVLEDVQFYRDQARASTKLMERDYNRCREEQNGWEDLTDSAHLPMPLSAAALRWRGAVSSDPHLSSKSNREATVNFEQGLSTAPSVMEHNQFRKRVGRGGRLFLDRIVAPRQRRCTRAWLDAELAGDSEESARDRRLTDRWRYDDDLRQDFPSTDYPHIIDDYNVTYSARRSQLLDQDDLQYLDPPGEVYLAKVAEYYDRAPQPEPTIVKVGKLPSKVVPNLYGAGLGCPTFPSSGPAVTMPEQLLAAHASAQVPNLRLNPTGKRATPNGTGPAVNRTPTSTQASTRTRKNPSVNGSPTANANAKSSSLQGQPPIQQMVWY
The following text describes a protein:
Function:
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPLLPIIAIALLIKGRAARWPMSLLLWGCTFGHSEARLQTLQADFVRWFRDNVTAFPLVQERLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRVNLIASQIQRGYGGWVLTMRCLGHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQHRWRVTPRGELQQLE
The following text describes a protein:
Function:
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MGSDYRSKKREILWKKSILHFSLCFIMGFMFGFAPTTTSHQSSIKPHDNSVQSTAAPITTTVEASLNSTEIDEDDEYGTPLILVTVTSSINPFKHTFLRRLSDTLKHVPAPLLWIIAENRLEAGSTAEMLRMTGIMYRHLTFNENFTDVETEMDYQRNLALKHIEYHRLDGIVHFADLSNVYELNFFDEIRDIETFGTWVVASLSANGEVVIDGPVCSDSKVLGWSFNHSGVTDDDQSPLKLMSRNSVSGFGFKSSILWDPERWGRRVSETESMASINYVRQAMLEDESKLMAFPSDCSRIMVWNLHVPRTLFLGVGDQLT