lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the degradation of cineol (eucalyptol). Catalyzes the initial hydroxylation of cineole exclusively at the pro-R carbon to give the (S)-6beta-hydroxycineole. Cineole is the natural substrate of CinA.
Miscellaneous:
MISCELLANEOUS: It lacks the conserved threonine believed to be involved in dioxygen activation and instead contains an asparagine at position 242. It is the first isolated P450 using the flavoprotein cindoxin (CinC) as its natural redox partner.
Sequence:
MTATVASTSLFTTADHYHTPLGPDGTPHAFFEALRDEAETTPIGWSEAYGGHWVVAGYKEIQAVIQNTKAFSNKGVTFPRYETGEFELMMAGQDDPVHKKYRQLVAKPFSPEATDLFTEQLRQSTNDLIDARIELGEGDAATWLANEIPARLTAILLGLPPEDGDTYRRWVWAITHVENPEEGAEIFAELVAHARTLIAERRTNPGNDIMSRVIMSKIDGESLSEDDLIGFFTILLLGGIDNTARFLSSVFWRLAWDIELRRRLIAHPELIPNAVDELLRFYGPAMVGRLVTQEVTVGDITMKPGQTAMLWFPIASRDRSAFDSPDNIVIERTPNRHLSLGHGIHRCLGAHLIRVEARVAITEFLKRIPEFSLDPNKECEWLMGQVAGMLHVPIIFPKGKRLSE
The following text describes a protein:
Function:
Binds to the 23S rRNA.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAASSSTAATLSWSSSSFFQTFGNTVNESVKLPDKRSALLVLAQKKAKKTRKIILKEDVAELGKKGQLLDVKAGFYRNYLHPMGKAQIVTPLLLKEMKMEEERIEAEKKRVKEEAQQLALIFETVGAFKVKRKGGKGKQIFGSVTAQDVVDIIKAQLQRDVDKKIVDLPEIRETGEYIAQLKLHPEVTARIRLNVFAN
The following text describes a protein:
Function:
Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
Subcellular Localization:
Cytoplasm.
Sequence:
MIVVKIGGSVVCKDASKVIQNLPKYADRAVVIHGGGCLVNELLKRMGIEPKFLTHPGGLVSRYTDWETLKVFVMAMGWINKYIVASLHGLGVQALGLTGADLGVVVAKRKERVLVIDERGRQRVVDGGYVGKIAEIRVDKLTPPPLKVLAPVAVSEKGELLNIDGDQLAFDVAREAKAERLILLSDVEGLILGGKVVPRLTPEEAEKLVKSEEVRGGMKRKLLMASEAAKLGIEVVISSGLVDSPIDAALNGAGTHIIKNI
The following text describes a protein:
Function:
Transcription factor that binds to the DNA sequence 5'-CCAACC-3'. Regulates directly PME5, UND and GLOX1. Essential for tapetum development in anthers and microsporogenesis. Regulates the timing of tapetal programmed cell death (PCD) which is critical for pollen development. May act through the activation of UND, encoding an A1 aspartic protease. Required for anther development by regulating tapetum development, callose dissolution and exine formation. Acts upstream of A6 and FAR2/MS2, two genes required for pollen exine formation. Negatively regulates trichome endoreduplication and trichome branching.
Miscellaneous:
MISCELLANEOUS: Plants silencing MYB80 have the majority of pollen grains distorted in shape with reduced or no cytoplasmic content, display early tapetal degeneration with large opaque bodies in the tapetal cytoplasm, and trichomes on cauline and rosette leaves contain increased nuclear DNA content and produces additional branches.
Subcellular Localization:
Nucleus.
Sequence:
MGRIPCCEKENVKRGQWTPEEDNKLASYIAQHGTRNWRLIPKNAGLQRCGKSCRLRWTNYLRPDLKHGQFSEAEEHIIVKFHSVLGNRWSLIAAQLPGRTDNDVKNYWNTKLKKKLSGMGIDPVTHKPFSHLMAEITTTLNPPQVSHLAEAALGCFKDEMLHLLTKKRVDLNQINFSNHNPNPNNFHEIADNEAGKIKMDGLDHGNGIMKLWDMGNGFSYGSSSSSFGNEERNDGSASPAVAAWRGHGGIRTAVAETAAAEEEERRKLKGEVVDQEEIGSEGGRGDGMTMMRNHHHHQHVFNVDNVLWDLQADDLINHMV
The following text describes a protein:
Function:
Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MAMTCIPEFHRLSLRIFLLLSASVLLCSHVVSIHSQKSEGALTVVENTDGGGGGTEEEEVVTVEDDDLEVVQPKEEWQTLKPGQAVPAGSHVRLNLQTGEREVRLGEEKLKYWTQEHREEEEESKSSFNFDELKRAMKKMKEELNLASKDKDLQDSLASRFRPLEELKKDMAELDLLVESDVQIMRRLLDQLNSTNTTTEQRLSILLELEYLVHQVDNAQTLCSMGGLQLILDGLNSSDFRLQESSAFVLGSALSSNPVVQVKAVENGALQTLLTTLATVQPVSVKKKVLFAVASLLRHFPFAQQHFVSHGGLQVLSELFRADVGGILQTRIVTMLYDMISEKELISQAGLDWVQDPSHEERVRQYSQVSLQGELLEKGWCSLVPQLLQSTEHDHREKALRALLAMAPVCLDRYRSDSALAGSLHSLRLQYQDIIQSDTILGEENGYFIELVELLDALQVKLK
The following text describes a protein:
Function:
Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQAAGHPEPLDSRGSFSLPTMGANVSQDNGTGHNATFSEPLPFLYVLLPAVYSGICAVGLTGNTAVILVILRAPKMKTVTNVFILNLAVADGLFTLVLPVNIAEHLLQYWPFGELLCKLVLAVDHYNIFSSIYFLAVMSVDRYLVVLATVRSRHMPWRTYRGAKVASLCVWLGVTVLVLPFFSFAGVYSNELQVPSCGLSFPWPEQVWFKASRVYTLVLGFVLPVCTICVLYTDLLRRLRAVRLRSGAKALGKARRKVTVLVLVVLAVCLLCWTPFHLASVVALTTDLPQTPLVISMSYVITSLSYANSCLNPFLYAFLDDNFRKNFRSILRC
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
ARIQIWLFEQKDLRIEGRIIGFDEYMNLVLDDAEEINVKKDTRKSLGRILLKGDNITLMMNTGK
The following text describes a protein:
Function:
May function as sodium-coupled metabolite transporter across the chloroplast envelope.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Plastid, chloroplast envelope.
Sequence:
MASAISLSLLNGATPLKSNSLHKSRLTPLHLRTISCSRLSYSPSSREISLKTQSTVPISCRRSRFDFVPRCGISSNDLPTEKKKSFGEWVEFVGEAVSTAFPIWVSLGCLLGLMRPSTFNWVTPNWTIVGLTITMLGMGMTLTLDDLRGALSMPKELFAGFLLQYSVMPLSAFFVSKLLNLPPHYAAGLILVGCCPGGTASNIVTYIARGNVALSVLMTAASTVSAVIMTPLLTAKLAKQYITVDALGLLMSTLQVVLLPVLAGAFLNQYFKKLVKFVSPVMPPIAVGTVAILCGYAIGQNASAILMSGKQVVLASCLLHISGFLFGYLFSRILGIDVASSRTISIEVGMQNSVLGVVLATQHFGNPLTAVPCAVSSVCHSILGSVLAGIWRRSAPKQLED
The following text describes a protein:
Function:
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. Required for centriole duplication and maturation during mitosis and subsequent ciliogenesis. Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MVPKSDQLLIVVSILEGRHFPKRPKHMLVVEAKFDGEQLATDPVDHTDQPEFATELAWEIDRKVLHQHRLQRTPIKLQCFALDPQTSAKETVGYIVLDLRTAQETKQAPKWYQLLSNKYTKFKSEVQISITLETDTKAQVDSFKAKGAPPRDGKVPASLLGVDPKDIVAVLNEEGGYHQIGPAECCTDSFTLSVTIAFATQLEQLIPCTMKLPERQPEFFFYYSLLGNDVTNEPFSDLINPNFEPERASVRIRSSVEVLRVYLALHSKLQIHLCCGDQSLGSTEIPLSGLLKKGSTEINQHPVTVEGAFTLDPPNRAKQKLAPVPVELAPTVGVSVALQREGIGSQSLIELKTQNGHEPEHSQKRVLTPIKEKTLTGPKSPRVSPAPPQNQTPPTKDDATESEVESLQYDKEPKQVVKGTGSIPASLAQPEATGNPSEVVTSGQKIAVPATSHHFCFSIDLRSIHGLEISFPVNCILRYSYPFFGSAAPIMTNPPVEVRKNMEVFLPQSYCAFDFATMPHQLQDTFLRIPLLVELWHKDKMSKDLLLGIARIQLSNILSSEKTRFLGANGEQCWRQTYSEKVPVIAAQGSNNRIVDLSYTMTLEDYGLVKMREIFVSESSQGMSAVGQRASPPPPPPAPCPSEIQVEPRETLEYKAALELEMWKEMQEDIFESQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYSILEGKLQQALTELESREQQLVTAETELQRERKELQLERERNLQELQDSVRRARDDCVHQVELERLKLKQLEEDKHRLQQQLNDAENKYKILEKDFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTEQQELLDIRNELNRLRQQEQKQYQDYKEIASGKQGSPRGSGLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIREVLTKNSASN
The following text describes a protein:
Function:
Acts as a transcriptional repressor. Capable of transcription autoinactivation. Binds to the consensus sequence 5'-C/GTAAT-3' in downstream activin regulatory elements (DARE) in the gene promoter, thereby repressing the transcription of CGA/alpha-GSU and GNRHR. Represses transcription of myoblast differentiation factors. Binds to core enhancer regions in target gene promoters of myoblast differentiation factors with binding specificity facilitated by interaction with PIAS1. Regulates, in a stage-specific manner, a developmental program of gene expression in the fetal tooth bud that controls odontoblast differentiation and proliferation of dental mesenchymal cells. At the bud stage, required for mesenchymal molar tooth bud development via facilitating reciprocal signaling between dental epithelial and mesenchymal cells. May also regulate expression of Wnt antagonists such as DKK2 and SFPR2 in the developing tooth mesenchyme. Required for BMP4 expression in dental mesenchyme cells. Also, in response to BMP4, required for BMP4 expression in neighboring dental epithelial cells. Required for maximal FGF4-induced expression of SDC1 in dental mesenchyme cells. Also in response to SDC1, required for SDC1 expression in neighboring dental epithelial cells. At the early bell stage, acts to drive proliferation of dental mesenchyme cells, however during the late bell stage acts as a homeostatic regulator of the cell cycle. Regulates proliferation and inhibits premature mesenchymal odontogenesis during the bell stage via inhibition of the Wnt signaling component CTNNB1 and subsequent repression of the odontoblast differentiation factors BMP2, BMP4, LEF1, ALPL and BGLAP/OCN. Additionally, required for correct development and fusion of the palatal shelves and embryonic mandibular formation. Plays a role in embryonic bone formation of the middle ear, skull and nasal bones. Required for correct formation and thickness of the nail plate. May play a role in limb-pattern formation.
Subcellular Localization:
Nucleus. Note=Interaction with PIAS1 is required for localization to the nuclear periphery.
Sequence:
MAPAAAMTSLPLGVKVEDSAFAKPAGGGVGQAPGAAAATATAMGTDEEGAKPKVPASLLPFSVEALMADHRKPGAKESVLVASEGAQAAGGSVQHLGTRPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKLDRTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYSASGPFQRAALPVAPVGLYTAHVGYSMYHLT
The following text describes a protein:
Function:
Specific chaperone for cognate PE/PPE proteins. Plays an important role in preventing aggregation of PE/PPE dimers.
Subcellular Localization:
Cytoplasm.
Sequence:
MTGPSAAGRAGTADNVVGVEVTIDGMLVIADRLHLVDFPVTLGIRPNIPQEDLRDIVWEQVQRDLTAQGVLDLHGEPQPTVAEMVETLGRPDRTLEGRWWRRDIGGVMVRFVVCRRGDRHVIAARDGDMLVLQLVAPQVGLAGMVTAVLGPAEPANVEPLTGVATELAECTTASQLTQYGIAPASARVYAEIVGNPTGWVEIVASQRHPGGTTTQTDAAAGVLDSKLGRLVSLPRRVGGDLYGSFLPGTQQNLERALDGLLELLPAGAWLDHTSDHAQASSRG
The following text describes a protein:
Function:
Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Serves a receptor for nuclear localization signals. Mediates the nuclear import of TATA-binding protein (TBP) and of histones H2A and H2B.
Miscellaneous:
MISCELLANEOUS: Present with 2940 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus, nuclear pore complex.
Sequence:
MDINELIIGAQSADKHTREVAETQLLQWCDSDASQVFKALANVALQHEASLESRQFALLSLRKLITMYWSPGFESYRSTSNVEIDVKDFIREVLLKLCLNDNENTKIKNGASYCIVQISAVDFPDQWPQLLTVIYDAISHQHSLNAMSLLNEIYDDVVSEEMFFEGGIGLATMEIVFKVLNTETSTLIAKIAALKLLKACLLQMSSHNEYDEASRKSFVSQCLATSLQILGQLLTLNFGNVDVISQLKFKSIIYENLVFIKNDFSRKHFSSELQKQFKIMAIQDLENVTHINANVETTESEPLLETVHDCSIYIVEFLTSVCTLQFSVEEMNKIITSLTILCQLSSETREIWTSDFNTFVSKETGLAASYNVRDQANEFFTSLPNPQLSLIFKVVSNDIEHSTCNYSTLESLLYLLQCILLNDDEITGENIDQSLQILIKTLENILVSQEIPELILARAILTIPRVLDKFIDALPDIKPLTSAFLAKSLNLALKSDKELIKSATLIAFTYYCYFAELDSVLGPEVCSETQEKVIRIINQVSSDAEEDTNGALMEVLSQVISYNPKEPHSRKEILQAEFHLVFTISSEDPANVQVVVQSQECLEKLLDNINMDNYKNYIELCLPSFINVLDSNNANNYRYSPLLSLVLEFITVFLKKKPNDGFLPDEINQYLFEPLAKVLAFSTEDETLQLATEAFSYLIFNTDTRAMEPRLMDIMKVLERLLSLEVSDSAAMNVGPLVVAIFTRFSKEIQPLIGRILEAVVVRLIKTQNISTEQNLLSVLCFLTCNDPKQTVDFLSSFQIDNTDALTLVMRKWIEAFEVIRGEKRIKENIVALSNLFFLNDKRLQKVVVNGNLIPYEGDLIITRSMAKKMPDRYVQVPLYTKIIKLFVSELSFQSKQPNPEQLITSDIKQEVVNANKDDDNDDWEDVDDVLDYDKLKEYIDDDVDEEADDDSDDITGLMDVKESVVQLLVRFFKEVASKDVSGFHCIYETLSDSERKVLSEALL
The following text describes a protein:
Function:
Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
Subcellular Localization:
Nucleus speckle. Chromosome.
Sequence:
MSFKEAKPGERGKNPEDHGRKQAASWMNGMEAANQPSTSAEKKSHHWRSYKLIIDPALRKGQQKLYRYDGLSFSMPNSGAPPVDSVRDPRIGRIWTKTKELDLPVPKLKIDEFYVGPVPPKQVTFAKLNDNIRENFLGDMCKKYGEVEEVEILYNPKNKKHLGIAKVIFATVKGAKDAVKHLHNTSVMGNIIHAELDTKGETRMRFYELLVNGYYTPQTLPVGSDLDASPTVNETPQVVEPVKRTKETAVGASVTPNSSTPFSHDTAYSSSRQGTPNSYSQFTPQSQGTPHTPRLGTPFSQDSSYSSRQTTPAFHYGQDSSFKPRRHENKFTDAYNRRPGHHYVHSSGSYRGPENTFNVTRPQAETVQFPRTPPLSHSSGNNKSAFSPYQGSTVFPQTDDNQYPQTSRDMEYRRTGPPTSDSYSDGSLELKLVKEKPEEPPPPEPDSTTEQKASFAQTPERCATPGTPTLEAEMQHDSLDTRIAMLLKEQRTQLHLISSDQNSDSEIRMEGSPISSSSSQLSPIPPYSSSSHYQDVTPSSRPSSTGLEDISPTPLPDSDDDEPIPGTASLCQNSRSASPIDQINQPVRKMETLDNKELVVGDETPTSEKMDEGHPSSGEDMEISDDEVTPSPITSAECAITSSSVIPILPPGFPPLPPPPPPQSGFPMPPPLPPPPPPTHPSVTVPPPPLPAPPGVPPHHILHHPPPYHHFPVMQGEMMNVLGNHWGGMTMSFQMQTQMLSRMMQGQGSYPYHHFMGGSMQFGNQLPYRPFALSAHLSRGQPWPPLPKFDPSVPPPGYEPKKEDPHKATVDGVLQVIVKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERLAKQSLTPVKSGESKDEDKQKTKEHITSSLLESWNKGEGLGFEGIGLGIGLRGAIRLPSFKVKRKEPPDAALAGDQKRIRPSHSVDDEDEESERDRDISGTASDLSKKDADAVNIRRRPARPLDSEGEEEVESEGDDGETSDKEAFEKEDQDAGSVSALSSKKRLYGEKEDEEDETQSSGKEEDLVSEEEDITSVASSRAEMDSSDESDESSEYESSSDSDDEIEEEDDDDEEEELVFEDDQSEELDLGQEDYIETDREEDFFKEDVSECSSPVKAEADMELEDDDVQKLEQDVAHQTAQDTSHLRKKDLDVPLVESKEHKQDTFDKMERLSAVPMQQNVFKEHEKAPSPMNEEEEYIELRLEPVPLVPDNAPPAVQEPMIIRPLTPTGAFGESGPVLKLEEPKLQVNLAHFVAEDEDLYPRTPGRDTAAHSDTEVTFQPGLKVAPSSLPLLQSHNKEEECLLPPEKHTGHLKVTKTLSEEELPRTPGRDILVKSSHLGKSQSTETIPATPGSDAPLTGNSLTLTSPHIPGSPFSYLSQSPGIINSGIPRTPGRDFNFTPIFPESNSIFPSHPSGKKSSVDEPDEKSFKEPTSASLTMNSVPSPIPFASPPRGVPHMDIRLETDDLESSDTQAYLSDKLLSEESECEFTKGQLPSTDESAPSPPFPPTDKRKGPKKPLAAHEFEACVALSEGALGKQLFIGQPDSVSGIKDPAAVPLDFRNDGLSENTVHDPIIQKVPLKELENQWNEVLKEEEEDISKHKKSRNSRLNKLYDEFSTLPSPEYSPPRAMFKPRSEFEEMTILYDIWNGGIDDEDMKYMCITYDRLLQQDNGMDWLNDTLWVYHPPTSVYSPKKKKRDDGLREHVTGCARSEGYYKIDKKDKLKYLINNRSLADEPPIDTQGKSIPAQPQASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKIRFCKSHIHDWGLFAMEPIVADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVVTVESQKKIVIYSKQYINVNEEITYDYKFPIEDVKIPCLCGAENCRGTLN
The following text describes a protein:
Function:
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (By similarity). Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MANRKIFLITSLIISLLLIHIFIFSPLNEPEKNAKAGPLGLSDVSVPSAPKLPAKDSTDFEVFLENPVIIFSRPGCPYSAAAKKLLTETLRLDPPAVVVEVTDYEHTQELRDWLSSISDISTMPNIFVGGHSIGGSDSVRALYQEEKLQSTLDEWTHNKVLILPTD
The following text describes a protein:
Function:
Orphan receptor.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVCSAAPLLLLATTLPLLGSPVAQASQPVSETGVRPREGLQRRQWGPLIGRDKAWNERIDRPFPACPIPLSSSFGRWPKGQTMWAQTSTLTLTEEELGQSQAGGESGSGQLLDQENGAGESALVSVYVHLDFPDKTWPPELSRTLTLPAASASSSPRPLLTGLRLTTECNVNHKGNFYCACLSGYQWNTSICLHYPPCQSLHNHQPCGCLVFSHPEPGYCQLLPPGSPVTCLPAVPGILNLNSQLQMPGDTLSLTLHLSQEATNLSWFLRHPGSPSPILLQPGTQVSVTSSHGQAALSVSNMSHHWAGEYMSCFEAQGFKWNLYEVVRVPLKATDVARLPYQLSISCATSPGFQLSCCIPSTNLAYTAAWSPGEGSKASSFNESGSQCFVLAVQRCPMADTTYACDLQSLGLAPLRVPISITIIQDGDITCPEDASVLTWNVTKAGHVAQAPCPESKRGIVRRLCGADGVWGPVHSSCTDARLLALFTRTKLLQAGQGSPAEEVPQILAQLPGQAAEASSPSDLLTLLSTMKYVAKVVAEARIQLDRRALKNLLIATDKVLDMDTRSLWTLAQARKPWAGSTLLLAVETLACSLCPQDHPFAFSLPNVLLQSQLFGPTFPADYSISFPTRPPLQAQIPRHSLAPLVRNGTEISITSLVLRKLDHLLPSNYGQGLGDSLYATPGLVLVISIMAGDRAFSQGEVIMDFGNTDGSPHCVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLTQVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSPGPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCPLGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRPSLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGVFILLFGCLMDRKIQEALRKRFCRAQAPSSTISLVSCCLQILSCASKSMSEGIPWPSSEDMGTARS
The following text describes a protein:
Function:
Involved in 20S proteasome assembly.
Sequence:
MTKSPFYTPTSSCKLDGTTLIIPAVSIGSVPQLAVDLLLHDASLSLVKVGRIDPSFCFPFVGPSETEDAYDITTSLEVFCNGSVTVIQQRSPVYKSLNSSYICALIDWITTSHFKEVLWLTSIDAAARTDDEFCTPILSLLPANSTPSTRILASLQTSFPQFNPPSIQSLQIPTKTHIDVPHIPGSLLTRKLLHHISHSSVKDSFGALLYFAAEGDTRPDAHNLATLVVSLLSTTTTPQLLLKEPRSWSALFGRPAASALYA
The following text describes a protein:
Function:
Degrades hyaluronic acid (HA) and chondroitin sulfate (CS) A in vitro. Is not active against heparin sodium salt (HS). Involved in the pathogenesis of vancomycin-resistant E.faecalis infections. Contributes to attenuation of the lipopolysaccharide (LPS)-mediated nuclear factor (NF)-kappa-B activation assayed in the mouse RAW-Blue reporter macrophages.
Subcellular Localization:
Secreted.
Sequence:
MKNRKIWVMLVGLFTALTNGFMGTTLTFAEENEASQTIEQPSYISDFPNQVGHWQDLVGTAEKKNDSAGLWIANTKQGTNLESVSINLDAREQSSGDLELTFLYEGQSNFGLVFRGDKQKTSQWQSFAYNRDGRWQLGQPGGKWLTNIPGPTLLSGQQYKLLVRYDGKKIQTFLNDQLFYENEEVHYPDGTSINDDWMGAVGIRLFGNLSKLNIISMKSGPVGSIPVIDSSAEYRELKEKWRNQLVSKEYDSTNQALVDYVQKISNEATELDQTMNKEPNRSYLWPLEPGNTPSADLTTQFTKLQKLALAYGTKGSTLYQDDKLAATIIDGLDFMVTQKGYDGKKYHGNWWDWQIGVPQKFLNILMILEDKVSPEKQQIYTNALSSYVPDPFKQLYTKPQGTFVDLAFIPNFVTSGANRTDLALTVLGLGILQKDSGKINQASSSIVDVFKLVTKGDGFYQDGSFIQHNNIPYTGSYGNVLVKGVGQILAITADSSFQMDATLVTEFVENVDRAFLPLIYKGEMLPTVNGRSISRAPAVGKTGYGSTTMYNLLIVAKFAPNNYQKKFQEAVKYWMKENPDYYLTNARDFNDLQMTMQLLTNPEITGGQLPFTGTKLYASMDRFVQRTPSYMFGLGLYSKRTASFEAGNKENKRGWHTGDGMMYVYNDDEVQFNSSYWPTVDPYRLPGTTVDTISLADEVSAFTTITSKEQWVGGVTSDNQAVVGMALNKDGTKNNGKLLPMNLQAKKSWFVLNGQIIALGAGIKGDTEASIETVVDNRLLNDAYQYQVLSNIGEIHEKNETSKKQWLLLKSDHSNANMGYYFPEETTVNVKSETRKGTYKAINEAFPSDKEYVGDYRTFTIQHGQHPTNEHYAYVVLPGIDETDLKTYAAKKTVEVLSNTEEIQAVKQEEEGYLGVNIWSETGGTIAGITSNKAISLMRKTQQHQKTYTFSDPTQTTKTLTLKIPKDYSTVISQSDGITYDDATETFTINFENAAGSSKQIIVE
The following text describes a protein:
Function:
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
Domain:
Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
Sequence:
MSGRISDRDIAAIREGARIEDVVGDYVQLRRAGADSLKGLCPFHNEKSPSFHVRPNHGHFHCFGCGEGGDVYAFIQKIEHVSFVEAVELLADRIGHTISYTGAATSVQRDRGSRSRLLAANAAAAAFYAQALQSDEAAPARQYLTERSFDAAAARKFGCGFAPSGWDSLTKHLQRKGFEFEELEAAGLSRQGRHGPMDRFHRRLLWPIRTSAGEVVGFGARRLFDDDAMEAKYVNTPETLLYKKSSVMFGIDLAKRDIAKGHQAVVVEGYTDVMAMHLAGVTTAVASCGTAFGGEHLAMLRRLMMDDSFFRGELIYVFDGDEAGRAAALKAFDGEQKLAGQSFVAVAPDGMDPCDLRLKCGDAALRDLVARRTPLFEFAIRAAIAEMDLDSAEGRVAALRRCVPMVGQIKDPTLRDEYARQLAGWVGWADVAQVIGRVRGEAKRTKHPRLGRLGSTTIARAAQRPTAGPPTELAVRPDPRDPTLWPQREALKSALQYPALAGPVFDALTVEGFTHPEYAAVRAAIDTAGGTSAGLSGAQWLDMVRQQTTSTVTSALISELGVEAIQVDDDKLPRYIAGVLARLQEVWLGRQIAEVKSKLQRMSPIEQGDEYHALFGDLVAMEAYRRSLLEQASGDDLTA
The following text describes a protein:
Function:
Transcriptional repressor involved in organogenesis. Plays an essential role in ureteric bud invasion during kidney development.
Subcellular Localization:
Nucleus.
Sequence:
MSRRKQAKPQHFQSDPELARLPRRDGDTEKGQAGRSAKSKGAHVCGRCCAEFFELSDLLQHKKNCTKNQLVLIVNENPASPSETFSPSSPSDNPDEQMNGLVNNTDRVDCSDLSEQNKLDREEESMEVEAPGAHGIGSDAGSLNESITSSNSSSMGTSAIATSLPQIGDLAALGNFSVINSNVIIENLQSTKVAVAQFSQEARHNGASPHKLAVPALMEQLMALQQQQIHQLQLIEQIRHQILLLASQNADLPTPSGSPQGTLRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASIGGVKHLPPIQLPQSNPGSAVIPPGNRSSPNISILAAAVPAPSSDKAASGVGGPQLGALPAATSSSTSSSSSSSSSSSSSSSPAFAISSLLSPASNPLLPQPAPGNPVFPSPLPSVGTAAEDLNSLSALAQQRKSKPPNVTAFEAKGASDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNIPTSTGIPYGMSIPPEKPVTSWLDAKPVLPTLTASVGLPLPPTLPTLTPFVKTEEPPPVPIGHPSGSPPASVESDPGAADPAPRNPGGLPEAAEGGDGPPLGPEEGAPPSGPLPRPRSAVGSPAADPGPGPAATPFPGPLGPLVSEQFRARFPFGGLLDAAPASETSKLQQLVENIDKKAPEPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVADHSYPESMESDAGSFDEKTFDDPDDFSDENMEDGPDGGVPPGTPRSADASHGSPASSPLPPEMSSIAALENQMKLIDAGLAEQLQASLKSVENGSAEGDGLTNDSSSAGGDAESQSAGSPALSESTSSTRAPSPAASSHDYGKSPSVDEKPPPRAPPGDFADGPSPAPANGGALDLTSGHPEKLVKEDSLGLLFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPSSTMGPNQNSAALPASALSSLIKTEVNGFVHGSPQESKDAPPGLAPTGPLTSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMTFLGGNPVKFPEMFQKDLAARSGNGDPSSFWNQYAAALSNGLAMKTNEISVIQNGGLPPIPGSLGNGSSSPISGLTGSLEKLQNAEPNAPLAGLEKMASSENGTNFRFTRFVEENKEIVTN
The following text describes a protein:
Function:
Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination. The velvet complex acts as a global regulator for secondary metabolite gene expression. Controls the expression of the sterigmatocystin and penicillin gene clusters. Represses the cryptic ors gene cluster producing orsellinic acid and its F9775 derivatives in a laeA-independent manner. Required for full induction of faoA gene expression by fructosyl amines. Positively regulates the expression of the early sexual development gene esdC. Controls the expression of mannoprotein mnpA.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Enriched in the nucleus in the dark. Migration to the nucleus depends on the importin alpha carrier protein KapA. Migration to the nucleus is also controlled by llmF.
Domain:
The C-terminal PEST domain is a region rich in proline, glutamic acid, serine and threonine residues that is required for the light-dependent regulation of development and secondary metabolism.
Sequence:
MATLAAPPPPLGESGNSNSVSRITREGKKITYKLNIMQQPKRARACGQGSKSHTDRRPVDPPPVIELNIFESDPHDDSNKTDITFVYNANFFLFATLEPERPIATGKLMTNQGSPVLTGVPVAGVAYLDKPNRAGYFIFPDLSVRNEGSYRFSFHLFEQIKDPKDATEGTQPMPSPVPGKLSSPQEFLEFRLEVISNPFIVYSAKKFPGLTTSTPISRMIAEQGCRVRIRRDVRMRRRGDKRTEDYDYDNERGYNNRRPDQYAGSDAYANAPERPRSTSISTNMDPYSYPSRRPSAVEYGQPIAQPYQRPMASTPAPSSTPIPAPIPMPGPVALPPSTPSPASAHAPAPPSVPLAAPPPLHTPSYQSHLSFGATQTQYPAPQLSHIPQQTTTPTHPYSPRSSISHSRNQSISEYEPSMGYPGSQTRLSAERPSYGQPSQTTSLPPLRHSLEPSVNSRSKTPSNMITSLPPIQSLSELPSTTSQPSSAIGSSPANEPGPRLWETNSMLSKRTYEESFGHDDRPLYNGMRPDSESYPGGMQRRPSYERSSLLDGPDQMAYKRANGRMVSKPATMR
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MKILKLPWLTHQEGQRNYEIYTVDVSSDGQRVATGGLDGKIRIWSVADILVFAKPKVSWPAREEQLRKPLANMSRHTGSVTALKFSPDNKYLASGSDDKILLIWEKEEGAVQPLFDMENDLEHWNVRRRLVAHDNDIQDICWAPDSSILVTVGLDRSIIVWNGSTFEKIKRFDVHQSHVKGVVFDPANKYFATASDDRTVKVFRYHKGTDLSFTIEHIITEPFQGSPLTTYFRRLSWSPDGQHIAVPNATNGPVSTVAIISRGNWDTSVSLVGHDQPTEVACFNPRLFEHNDNHERGEEVDGASKDNSAASESSGKRRLKDDDRVDSVIATAGQDKTLAVWSTSRARPIFVAYDLTSKSVTDIAWTCDGTALFLTSLDGRIIVITFEEGELGKAIPLEQNVEQLHRYGVDKDSLVFPESVKQLILEDKARQYKKPYIETTLLESRIGTVKKPNVLNPRPKHAKNDVAVASIPQAQAPALKKKEGPLNAATVQNGKKRVAPTLISTGYARAATVKFEPRSSIDSDFAGKKEPLKDTSYALAGKISQPSLPLPRLGVHTLIMGVKERGAERFYVEDEESMDDDAEVADEEDETKNEHPLTLNLKTTPERVWKDEPNLRYLEYPGVIPDADVVICQYGDLDDLHILEIRNGVERSIQFDREALFENPTKILGYHQGERTLEAFLPEVVISCVGSKACQCWALATASGSLYIYGNHGQLLVPKISIGHKVIKLIAWQHFVIAFTETCLFWIWDIRAMKLVEKEISVLPVLVQDQPQCNRVRISRRILDFRMLADSHELLVEMSDGASYVWKRALGCWTDTIGQSTPVTA
The following text describes a protein:
Function:
Required for peroxisomal protein import which maintains the function of peroxisomes.
Miscellaneous:
MISCELLANEOUS: Present with 8970 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MVVDTEYYDLLGVSTTASSIEIKKAYRKKSIQEHPDKNPNDPTATERFQAISEAYQVLGDDDLRAKYDKYGRKEAIPQGGFEDAAEQFSVIFGGDAFASYIGELMLLKNLQKTEELNAEDEAEKEKENVETMEESPADGKTNGTTNAVDAALGNTNEKDDKNKARTTSGNLTVHDGNKKNEQVGAEAKKKKTKLEQFEEEQEVEKQKRVDQLSKTLIERLSILTESVYDDACKDSFKKKFEEEANLLKMESFGLDILHTIGDVYYEKAEIFLASQNLFGMGGIFHSMKAKGGVFMDTLRTVSAAIDAQNTMKELEKMKEASTNNEPLFDKDGNEQIKPTTEELAQQEQLLMGKVLSAAWHGSKYEITSTLRGVCKKVLEDDSVSKKTLIRRAEAMKLLGEVFKKTFRTKVEQEEAQIFEELVAEATKKKRHT