lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MHKLVLQSKINETKDVMKRKASEIDKSKIEKSRGDKGGFGPLQLMGSGRIENSFSDLSISSSGTGFESGSGFGLTSDVDSFATKPKGHPTSSATAPPKGLGMKLESLKAKGEVILEDVQPKHSESWVVAPQLTDPITLTVEEKLNSKEVCQPMNPTTGIKNENVPLSITNGLLAEPIKNGSRGRHVDSLHHVEPRNDTNILGGLTLWVIEVNRHRDNHIPYGVECLAAWSFTAMLISYFVSRKGTSGGVVQ
The following text describes a protein:
Function:
Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.
Subcellular Localization:
Nucleus.
Sequence:
SSAQRHPSSTMTDGRIYIGNLPIDVQERDIEDLFFKYGKIREIELKNNRGTIPFAFIRFEDPRDADDAVYGRNGYVYGNSKLRVEYPRSTGGKPTPMGPGGAGPRGRFGPPTRRSEFRVIVTGLPPTGSWQDLKDHMREAGDVCFADVQRDGEGVVEFLRREDMEYALRRLDRTEFRSHQVIGQSMLGSTSWARSRSRSRSRGRYSPPFYNRGSPPPRYQSPPRHAMRHSPPPRRHPPQHSPLPRHYR
The following text describes a protein:
Function:
Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
VMEYMASHMQNSGLTLSVQNKTRKKNPPEAEQHPSITSIPEPSRVLTQANAVRMLVTRRCTILGPLGVRNYQEDISLSSEKAPCIRLQSLEDLVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSNLVSANRLFGDKSLTFNESYQDVSEIVYGAKLQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAIDELTALVLVNTIYFKGLWKSKFSPENTRKEPFHKVDGQSCLVPMMYQEGKFKYRRVGEGTQVLEMPFKGDDITMVLILPKPEKSLAKVEQELTPELLQEWLDELSEVMLVVHVPRFRIEDSFSLKEQLQDMGLVDLFSPEKSQLPERFGSGMTVMTAQWRVLAEHTPDSQAPHPVLKGQGERDLSKAQVAQQTGQMGMSGSGVTKAQCSSKTEEELSQGKVETPKDLKMSNSLISISDQRTAGFRHRCPHGTGEEKARTLRTSSLLSEPTVAPQLLTKGGNTSFSKAISICFKMRLQAELNPQVVATHSSWCDCPLKGKEDCQSIGLSFACLALFLCNHPRSTNWRPRDSREVLNEYNMPGHGLLNPVLTQALGICFAESYTQAQWFTRQPLAVLS
The following text describes a protein:
Function:
Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytosol. Nucleus.
Sequence:
MEPQKIMPPSKPHPPVVGKVTHHSIELYWDLEKKAKRQGPQEQWFRFSIEEEDPKMHTYGIIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGDCEYSPLVSVSTTREPISSEHLHQAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDRGADASVKNEFGKGVLEMARVFDRQSVVSLLEERKKKQRPKKSCVC
The following text describes a protein:
Function:
Regulator of cell size that promotes cell size increase independently of mTOR and Hippo signaling pathways. Acts by stimulating the translation of specific mRNAs, including those encoding proteins affecting mitochondrial functions. Increases mitochondrial mass and respiration (Probable).
Miscellaneous:
MISCELLANEOUS: Overexpression causes embryonic lethality. Conditional overexpression leads to increased cell size.
Sequence:
MSAKSKGNPSSSSAAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSIEKIKEQANAPLIKPPAHPSAILTVLRKPNPPPPPPRLTPVRCEEPQRVVPTANPVKTNGTLLRNGGLAGRPNKIPNGDICCIPNSNLDKAPLQSLMHRPEKDRSPQAGPRERVRFNEKVQYHGYCPDCESRYNIKNREVHLHSEPVHPPGKIPHQGPLLHPPPHLPNFPLENGGLGISHSNSFPPPTPATVPPPAAPKPQKTILRKSTTTTV
The following text describes a protein:
Function:
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
Sequence:
MKIKSLEEIYLFSLLIKESEIIDFFLGASLKDEVLKIMLMQMQTWAGQRTMFKAIGDYDGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTCSYLTPDLWK
The following text describes a protein:
Function:
Regulates cellular transport and efflux of cholesterol. Plays a role in phosphatidylinositol-4-phophate (PI4P) turnover at the neuronal membrane (By similarity). Binds via its PH domain PI4P, phosphatidylinositol-4,5-diphosphate, phosphatidylinositol-3,4,5-triphosphate, and phosphatidic acid (By similarity). Weakly binds 25-hydroxycholesterol.
Subcellular Localization:
Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope. Cell membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Co-localizes with OSBPL3 at contact sites between the plasma membrane and the endoplasmic reticulum.
Sequence:
MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 and its co-chaperone (MGE1) to drive protein translocation into the matrix using ATP as an energy source.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein.
Sequence:
MHRSTFIRTSGTSSRTLTARYRSQYTGLLVARVLFSTSTTRAQGGNPRSPLQIFRDTFKKEWEKSQELQENIKTLQDASGKLGESEAYKKAREAYLKAQRGSTIVGKTLKKTGETMEHIATKAWESELGKNTRKAAAATAKKLDESFEPVRQTKIYKEVSEVIDDGESSRYGGFITKEQRRLKRERDLASGKRHRAVKSNEDAGTAVVATNIESKESFGKKVEDFKEKTVVGRSIQSLKNKLWDESENPLIVVMRKITNKVGGFFAETESSRVYSQFKLMDPTFSNESFTRHLREYIVPEILEAYVKGDVKVLKKWFSEAPFNVYAAQQKIFKEQDVYADGRILDIRGVEIVSAKLLAPQDIPVLVVGCRAQEINLYRKKKTGEIAAGDEANILMSSYAMVFTRDPEQIDDDETEGWKILEFVRGGSRQFT
The following text describes a protein:
Function:
Involved in the maintenance of DNA methylation. Binds hemimethylated DNA.
Subcellular Localization:
Nucleus.
Sequence:
MMRYEDVSQLSLMNLTYEEQRLENIRKNEDLLRSLGLGAPSEATTLATPSNLKTAGNQRRYNDTLVGKSNTGRNRSDSPRKRPTKDREDLNLVPQSAIKRRQSVRLGGKEKPNYTREQVTFNSDRDTPNTPSRQIKSTHSHPGSEEEDIRQVKTRTLGVRVHNPKTFGHIPGIGVGKWWATRMEASADAVHAPTVAGISGNAHEGAWSVALSGGYPDDIDLGYAFTYTGCGGRDLKGTKQNPKNLRTAPQTSHQSFDNPLNAALKRSAETRNPVRVIRGFKLQSKYAPPTGYRYDGLYIVEKAWMAKGLTNGLMVCRYAFKRMDDQGPLPQKDLDHDDDNKA
The following text describes a protein:
Function:
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
Sequence:
MIIKPEPSLKDLSYIIENAGLKASDLLNMYKRMLIIRYFEESIRKIYHEGKNPFNMASGRIRGEMHLSIGQEAVAVGTLYDIRDEDVVVSTHRPHHHAIAKGVDLKGLAAEILGKATGLCKGKGGHMHLFDKSKNFACSGIVGASFPQAAGAAFAFKYLGKDNVAISFAGEGAANHGTFAETLNIASAWELPLIIVIEDNKYADSTPKSFVMSTTFHYQRGLAYNVPSYLVDGMDVIDVYSTSKKAIERARKGFGPTLIEALTYRYVGHFEGDGEEYRTKEEVEFWSSLDPIRRLENRLLRLNYADSDILARLREEARKQVQEAIDFAINSKYPELTDAFGGVFA
The following text describes a protein:
Function:
Regulates the motility of migrating epithelial cells by providing guidance cues within the migratory environment and may also play a role in development of the olfactory system. May act as a positive axonal guidance cue (By similarity). Function in neurons is essential for adult survival and is important for climbing behavior. Promotes collective migration of follicular epithelial cells in egg chambers, likely by acting at the leading edge of the basal epithelium cells to provide guidance cues across the cell boundary to the trailing edge of the cell ahead. The transmembrane receptor PlexA on the trailing edge of the cell ahead, appears to transduce this signal to suppress the formation of protrusions. Involved in olfactory avoidance behavior.
Subcellular Localization:
Apical cell membrane; Single-pass membrane protein. Lateral cell membrane; Single-pass membrane protein. Endosome. Note=In egg chambers, detected on the apical and lateral membranes of the epithelium, and detected in intracellular puncta that may represent endosomes. Punctate and planar polarized at the basal epithelial surface, with enrichment at each cell's leading edge.
Sequence:
MNMLILKLPKMFSQLWLLLILSLLTLEGPQPSTGSGYTTKSSVDLLENDSRYISYQDLMSTAKRFYDPETTWYSEMLFDVARNQVIVGARDTLYRMSFDLEPLERASWGATPSEIAMCQAKGQSERWCRNYVRVLHSYGENQLYACGTNAFQPSCSWRQMENLTVTGVDSGVVKCPFHPQANSTSLLQSNGQLFVGTATDFSGSDVAILRTGVESNKRFLRTKQYNNNWLSGAQFVGSFEAGHFVYFLLRESAAEHMSCGKVIYSRVARVCKNDVGGGGQLLRDNWTSFLKARLNCSLPGEYPYYFDEIQGMTYAESESILYATFRTSGSSIFGSAVCAYNLSSINAAFDGPFKQQEHSDAAWKTVNTNQRSQFQCGTSSIGHWLESSRYQLMDEAVQPIGAEPLYHSKLEQFGRLALDIINTKTEQVHVLFVASSGNHIKKLSVKYDGDGVQTCLVELWQADDTGTSSLLNMAYLKVSDSLYLGTDLALTRIPAQHCSRHVSQSSCLNSMDPYCGWNELVERCMPQPQDSSVLQHWHQAPQITCPVLNAPIDGGWSTWSPWAVCQQHEQPDSNCQCRQRSCNNPQPQHGGATCEGISTQVTNCTQHGGWTEWSAWSPCSQTCGIAVKIRRRTCGNPRPAFGGRTCVGSEQSEMYCRHLPPCPVAKPQSVDGGWGPWGEWSECSAQCGGGFRMRRRECNDPAPLNGGMECPGCRLDYEECNMQSCQEVRKLSAWTPWLTVTGSGNSSEPHMERRFRFVCRATSPDPSSVRIGLPKEESRNCHADGSCQRQVDHDSADSDAADWSPCSVSCGGGVQQRHRGRGSQSRVCNIHACPAEEQLSSNSLDNELEHGEWGCWSEWSACSVTCGLGLRRRTRRCLAGHDRLCQGRALEEQKCEMVPCEDFLGWSAWSEWSSCSSDGIRLRHRRCLVEQPGSMECRGAEFEKTACVPNECEETQTASTATLPIVIFVGLLFTVACCLATYRFTKKRFMLSAEEALNKTTTTTASFDTYPNQYSSLPTKDYYDQRPKRQSSFRMPAKTSNLGNGNGTLNRNNMHQNNTPKVLAKTYIDCESGTIKRQSALNNCRSNIDDEKF
The following text describes a protein:
Function:
Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).
Subcellular Localization:
Nucleus membrane. Nucleus, nuclear pore complex.
Sequence:
RSDLPEILEQTSGGARIRTQGLLTPRGILSRVTESVKNIVPGWLQRYFNKNEDTCVCPTDTGESRLWPENAENDHLIYSDEESPVIHDGRITPEPAVSSEEEPSTSRSALNFPDVLTRPSLHRSHLNFSVLDSPALHCQPSTSAAFPIGGSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDLAVSKNPSMPPLWSPEAERPHTLSQHTAASSKKPAFNLSAFGTLSPSLGNSSALKSSHFGDSPFYPGKTTYGGAAAAARQSKVRNTPYQAPVRRQVKAKPVNSQSYGVTSSTARRILQSLEKMSSPLADARRIPSAISSPLSSPFDRSGLDTADLQSKRKKVDSRTPPVQRLMTPKAISIATNRSVYFKPSLSPATELRKTSQRIDLKHNVSISSFLLIFLSLRNDVEVPVLPKISLPISTASLPSFNFCSPTSSTASSSPIRMAQPSANKVQATPPSNPGSPVFRFSSPIVKSTEAEVLPPSSIGFTFSVPVVKSAELPGFGNSSQPTRSSTDVTAVNSTSNKKENEDYEGPFKPAKSLKEGSVLDILKSPGFTSPKASPLPTAQPPATSTVVYTRPAISSFSTSGMGFGESGKAGAQWQCDTCLLQNKVTDGKCVACQSARMPPRDPAKPGGSAAPSSEAKPTPPATGTVGFGDRFKPAAGTWDCDTCLVQNKPEATKCVACETPKPGTGVKPALTLPVASESSGAVTTSSPRCTVTSGTLGFGDKFKKPKGSWECPVCCVQNKAEDSKCVACSSEKPAPVASNSSPAVSAPSGGFLGFEKFKKPEGSWDCEVCLVQNKAEATKCAACESAKPGTKPEVKGFGTPTTSSASSAAPAPAFKFGLPPSSSEPPPPPPTAPASSTGFKFGDPGGFKLGASSSDSAISNPMSGGFKFSQTVGDFKFGVSSSDSKSEEVKKDSKGDSGFSFGLASGLSNPPPTAGFQFGTPSLGPQEKKEELGKPAPGGFAFGTGSVSAAPAPPTENKTGGGGFGFGAAEAKPAAAAAATTPFLFPKSEGSKDGGPAAQGGFSFGGLEPAARLPSAPVFGLGRTEEKKPEPVTSATGLVFGKKTGGEEPKSQLLFSFGKPEQTKDESPAKQAFSFSLAKPAEKEADPPAKSTFAFGVQAAAPADQGAGKPALSLLSSGSSNPSVPTTGATGTGGGSLFGGAASASNPPVATFVFGQTGNAVSGSAFGNPLESGAPQPFSFSQESKPAAAPAAAAGAAVAPFVFGPGAGGGGNPATSTFSFGASTTASSSSFVFGSGTAAASASPVFGAGQTPTFGQSQGAGQPSGPGFGALPSSTSLFSAGSQPPLPTFGSVSSSGQPPVFGQPPSQQAGFGSGSAPSGGVFQFGSSTTNFNFTSNNPTGVFTFGANAAPPAPSAQPSSTAGFPFGPVPAFAVGTNGKNVFSASGSSVSGRKIKTAVRRRK
The following text describes a protein:
Function:
RNA replication. The central part of this protein possibly functions as an ATP-binding helicase.
Sequence:
MALVSKVFDSITDPSLRAVLQEEAHSQVKQVLKDTALYSRYALLPTAANTLERYAIPHNPFSTKLHTHAAAKALENDLYRTASYLLPKERVSFLFMKPSKMQYFRRRGDVDTFINADIVAKDLARYPLETIYPRLPEITTKMAFIGDSLHYFQPEVLEHIFASSPQLETLLATIVLPPEATLRLKSLYPEIYTLHYMPQKFLYKPGGLSGGEYEHDYKDLTWLKIGHVTTASMCLTVDRVESKAANHLLLIRRGRLKLSTYRSYDTPEPLVVVPKIFLPPKYNAQKPITKTKANSWILYVKSAGEPKIRDVWAKLRQTIANSELNQYEPAELLLLTNYFYVLGKLDSITSFETLLGDNILKRLFRPAIAKIQELRHWVSGPTAFMQLYKALQLVDVDFTFEVTKNWETKQENHHEPELPKDAIDMLVQSLIGINYTDAATAEATSPNQQASESKPQSDLPQPLQQTKCPEDAEAPAPLECKTAETAQEACKAGPSSNPTLNTSQEAPPSELKNSEERTCPTLRELPWKAWLKLLRGLGFQGDLEQLDIEGDPIYPIKHIRHLPVEEFNSPITATLRKMNRMPCKYSPDIERAAAFARDVMSNKTGAILPKQSHEWKTTLKRKCKLAPRQTLISVIHGAGGSGKSRALQEYMRNNKEDPIVTILPTNELRADWKAKLPAHDPDMFMTFENALLIPKGNVVIMDDYTKLPRGYIEAYVQNSPMLDLLILTGDPRQSEHFESVEGNTINDLSPSPVVFSAYARYYINATHRNNQDLANALGVYSEKQGKTRISVSNHIEDGRHTLVPSQIKQRNYVSMGRKTSTYAGCQGITASRVQVIIDNDTAKCSHQVLYTAFSRAADEIHFCNTMTDEKQFWAKVKCTPYLQAILNLTKEHSLPDPKPEPDEPLEPKAPVTHIAVENVVPLVEEITEPLPEKHDREIYSESTGHSNCIQTENEFIQAFQHQQAKDETLFWATIEKRIVTSTPESNWTEFKTKKPLGDILWLAYKEAMCLPAEPIKFDPDLWWKCADEVQNKYLQKPLHMIKNGILRQSPDFGERHIALFLKSQWVKKNEKIGTVNVKAGQTIAAFYQSTVMIFGTMARYMRLVREKFCPKNILINCEIDQPTASKWVDTHWKFDRLAYTNDFEAYDQSQDGAMLQFEVMKARHHDLPADLIESYIELKLNAKIFLGTLGIMRLTGEGPTFDANTECNIAYTHARFHIPRGTAQLYAGDDCALNCEPKERESFKPLRAQFTLKSKPVTIRQGKGSWPEFCGNIITPYGYLKHPRKTWAALHKAKLQGKNELKKTATAYALDVLPTYELGDAIHDIFTDNELTFHYQTIRTLHTEAHTRVFTNHDAIFGEEGLFSS
The following text describes a protein:
Function:
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
Sequence:
MPTGARILVDSLKREGVKVVFGIPGLSNMQIYDAFVEDLANGELRHVLMRHEQAAAHAADGYARASGVPGVCTATSGPGTTNLTTGLITAYWDSSPVIAITGNVPRSVMGKMAFQEADAMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATTGRPGPVVVDIPRDIFYEKMEEIKWPEKPLVKGYRDFPTRIDRLALKKAAEILINAERPIILVGTGVVWANATPEVLELAELLHIPIVSTFPGKTAIPHDHPLYFGPMGYYGRAEASMAALESDAMLVVGARFSDRTFTSYDEMVETRKKFIMVNIDPTDGEKAIKVDVGLYGNAKIILRELIKAIITLGQKRDKSAWIKRVKEYKEYYSQFYYTEENGKLKPWKIMKTIRQSLPRDAIVTTGVGQHQMWAEVFWEVLEPRTFLTSSGMGTMGFGLPAAMGAKLARPDKIVVDLDGDGSFLMTGTNLATAVDEHIPVISVIFDNRTLGLVRQVQDLFFGRRIVGVDYGPSPDFVKLAEAFGALGFNATTYEEIEKSIKSAIKEDIPAVIRVPVDKEELALPTLPPGGRLKQVILRDPRKSS
The following text describes a protein:
Function:
Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. May be involved in signaling by recognizing appropriately phosphorylated substrates via its arrestin domains and then recruit a HECT-type ubiquitin ligase such as hulA, leading to ubiquitination of the substrate, providing a link between ubiquitination and phosphorylation in protein regulation and stability (By similarity).
Sequence:
MALSFFSGGGSASYAKYFDIRLDEGYIVFRGGEQEAASAQLSGKLLLCLSEPLAAKHVRLNLTGISRVCWHLPSGSASGSRKSWREKVFYEKTWTFRDAGKSKTEVLAAGNYEFPFHVILEGSMPESVEGLSDTYVTYRFKAEIGRKYAKDIVVRKPLRIIRTLESSALELSHAMSVENIWPNKIEYSISTPTKAVIFGTSLRVDFKLIPLLKGLKIGQIVSQLIESHDLTLNPEDPDSIRNTYKSTRTIVSDEYELDDEGSLEIIDEEAEGYQFSRYLDLPKTLTRCLQDTDTRGIKIRHKLKFRVQLLNPDGHISELRATLPVSIFISPNLAIDENNNLVDQTPQTARRAVDDIAQQAPPLYGEHQFDQLYSEVDPSGYRTPGPGSGPGTPFGALSRNISSENLASMNALTSTDLSVSALQTRLSNLHASRFSNPSPTEIDNHADSEQRRLGISTADYFGPSSGSNSHSPASPELSRRPSDEGYRDHDHIPSGMATPFHPQYAEVETLSRVPSYSTAMRSTVRPCDSELPDYQAVVAEDTAMPALQSPQQAYIRSAGRGTSMNTGIDVHQLRSGHFSSRTSNSHDEEDRRLRLVQARARV
The following text describes a protein:
Function:
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
Subcellular Localization:
Cytoplasm.
Sequence:
MTLASAEKEMVGVLTFFQKETRGFRTGKAHPALVETVTVEVYGTTMRLSDIASISVSDMRQLLLSPYDAGTVSAISKGILAANLNLQPIVEGATVRINVPEPTEEYRREVIKQLKRKSEEAKVAIRNIRRTFNDRLKKDDNLTEDAVKSLEKKIQELTDKFCKQIEELAKQKEAELATV
The following text describes a protein:
Function:
Symporter that selectively cotransports sodium ions and amino acids, such as L-glutamine and L-asparagine from the lysosome into the cytoplasm and may participates in mTORC1 activation. The transport activity requires an acidic lysosomal lumen.
Subcellular Localization:
Lysosome membrane; Multi-pass membrane protein. Cell projection, axon. Note=In neurons, located in soma.
Sequence:
MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLSEMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA
The following text describes a protein:
Function:
Acts as a component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export. Contributes to the integrity of the endogenous trans-acting small interfering RNA (ta-siRNA) pathway. May process or transport a long RNA molecule so that it can be a template for secondary siRNA production. May participate in the trafficking of siRNA precursors to the ARGONAUTE catalytic center. Required for the generation of functional messenger ribonucleoproteins (mRNPs). Plays an important roles in plant innate immunity.
Subcellular Localization:
Nucleus.
Sequence:
MDAFRDAILQRAPIETFALKTVQHFIQPQKQTKLAQDENQMLENMLRTLLQELVAAAAQSGEQIMQYGQLIDDDDDDDDIHGQIPHLLDVVLYLCEKEHVEGGMIFQLLEDLTEMSTMKNCKDVFGYIESKQDILGKQELFARGKLVMLRTCNQLLRRLSKANDVVFCGRILMFLAHFFPLSERSAVNIKGVFNTSNETKYEKDPPKGISVDFNFYKTFWSLQEYFCNPASLTSASTKWQKFSSSLAVVLNTFDAQPLSEEEGEANSLEEEAATFNIKYLTSSKLMGLELKDSSFRRHILLQCLIMFDYLRAPGKNDKDLPSETMKEELKSCEDRVKKLLEITPPKGKEFLRAVEHILEREKNWVWWKRDGCPPFEKQPIDKKSPNAGQKKRRQRWRLGNKELSQLWRWADQNPNALTDSQRVRTPDIADYWKPLAEDMDPSAGIEDEYHHKNNRVYCWKGLRFTARQDLEGFSRFTEMGIEGVVPVELLPPEVRSKYQAKPNEKAKRAKKEETKGGSHETEGNQIGVSNSEAEAEGGRGDAETMESDAIADTPTPEEQQRLGGSDTENGQEAGQIEDGETEEAGLMDTDLDHPPMPVS
The following text describes a protein:
Function:
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
Subcellular Localization:
Cytoplasm.
Sequence:
MARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSGAERRDGKLIAGDANYVYNIANIKGDPNDAVSYIFQQAVSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGGIVCPISTGKERIMLHNIIKIFKLPAIVVADAGLGTINSTILTLQYMKEKNISVKMILLNNYNHKDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI
The following text describes a protein:
Function:
Transcriptional repressor.
Miscellaneous:
MISCELLANEOUS: Present with 704 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSIGYKDNLMSTILAKDRKCEFPINFECSPSQITLMPEMFSFNNERKYQTLIPLMKTSHLIDDDLKDKLNKCAFDFFSGKQANRTSDGTISRLTASGKTSPILPLQNINIVKAENTGNGKSDPYSSIKISKPTKTVIKLKSTKTNTAGQRTRHFCKICSTGFTTSGHLSRHNRIHTGEKNHICPHEGCGQRFSRHDNCNQHYRTHANKKKRNWKRREASS
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as a non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells; Glutamate-gated receptor that probably acts as non-selective cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDFARKAKWTFFVVTTLFSLVQPLSTNHTSINDTAIEMIHVGLILDAQSWVGKIVDSCISMAISDFYSQNCHYQTKLVVHTRDSGGDPLLLLSQALVLLENFKLDAIIVAENSAGVKILAELGSRVKIPIISLFAAGLSLSSFEYPHLIQIGEDESSRAKAIAAIVEAFSWRSVILIYEDNDSARPILSSMTGFRLDQHVALLTSSTDEEIVEQLMKLMSLQMTVYVVHMSPILASRLFLNAKQLGMLTQGYAWITTDMITNFMNSMDPSVFESMQGVVGFKPHIPASKELRRFAIRWRSKNLNENKNLEEMEMNVYGIWSYDMVWAVATAAERVMTRHPHILHQETRLNMNFTTIRSSESGLVFMDEILQSRFKGISGGFQLTNGRLIPKEIEIVNVFKGDRIIGYWNPENGIASIMKEENHTETNSTSSSKLEGVIWPGGTMNIPKGWSLRGKRLRIGVPVTNQFRELISVVHDPQTNDIIVTGFCVDVFKEAVQSLDYEVHYDFIPFEDANGRMAGSYDDLILQVYHKNYDAVVGDITITSRRFAFVDFTLPFTDLGIGVLVPKIDNDIWVFLKPLCGDLWITVGAFFIFTGVVIWFIERPINEEFQGSPSEQIGMIFWYSFSTLVFSHEKPLSNLSKFVVIIWVFVVLIITSSYTATLASMLTVKQIQLSSRDNDAWVSSDISNFTFETRRRRANHSAEEFADALRRGSKNGGESSIIDEIPNLKVFLAKYPSDYTMIKSKAITGGFGFVFPKRSPLVQDISSAIMRLREEKRLEMMENYWFNSESSFTTLDPESNPNRLNIHSFGGLFLVTGISSISALGVCLFQKRQSIKIHLNSSLDSLKGYFNVKIIGRQKERS
The following text describes a protein:
Function:
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MINLALVIFLCTLLNQIVSWVGKSVLQEIAFTAYSWVFLSGTAAKQRKLRKQVLEDKAELGRTSSQDEFAKWAKLRRKLDKGLADLEKTNNTLSSSRSSFSKKFSTLLWLMTTGAQFLLSWWFRKQPIFWLPEGWVPYPVAWLLSFPSAPIGSVSSGAWGAICRRVLSTLQEIIQSLLAPSPAATGPVPTGPSSAKNDQPEAKIEALALEHEKLD
The following text describes a protein:
Function:
Catalyzes the stereospecific oxidation of D-lactate to pyruvate.
Subcellular Localization:
Mitochondrion.
Sequence:
MWRKRSWGCHRQEWLVARIKGSSVGYDAVGVRVASKMYSRSIWRARAVPRMLTASRSFSARAAASTGWRLLSSRAGAGAILGALGVGGYLYYDQLPTRQVFPERSTTPLATLESPLYGGEKELKLAVLEIQRDIGKENVNAQEADLELHTDNQLNYTRPRKDYKPRYVVYPRSTADVSAIMKIAHKYSIPVVPYSGGTSLEGHWYSTRCGIVLDTSRMNKILRVSPDDLDVTVQAGVGWKQLNAYLQGHPGLEHLIFGCDCGPTAHICGMINTNASGMKATKFGPMKMNVISVTAVLADGTVIKTGRRPRKTSAGYNLTGLLVGSEGTLAVITEATLKLQVKSPSETVAVVQFPTLTNCTKTVSEIFKKGFQLNAIELLDSEMMKLVNHSKSVSKEYKEIPTLFIKVGGINKTVVKEYLKELRAICDNHKAASFEFAKSDAEAEELFTARANALYTMLEYCYTDIHEDAKLWFTDVAVPLSKLASTLEEIDELCEKYPMKHAMVGHVGEGNFHYNLLYRPEELEMSKEVVSKMVDIGLRNEGTCTGEHGIGLGKRRYLERELSPSTLDMMRKLKLALDPKRILNPDKVFKIDPADEDNHLSAGEPKELNT