lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
Sequence:
MEVAIKRDSSEDVLKTRLGTCEKCGAQEARYRCPRCEFRSCCLQCVNLHKKEFDCNGIRDKTRFKSLSQFTELDLLSDYRLLEEASRSVESYYRDVSKRSTRVNKELPTHLHKLRCTAAQRGVTLRFLPPNFTRHKLNTTYLDWKTKKIDWKVEWKFVWKDVTTVENRIPENELLRDVFTKTLEANSKNVSLNESDLNKVQIFLAAEHTPGQNGRFHLISLDKTLSDNLKGTVIVEHPVFQVVLDPADEYPLIGTPVRVREPKAKVERTAGATNSSGDNEQDGPDGKKQKLTFFDVSDGEGHSES
The following text describes a protein:
Function:
A potent antigen in animals immunized with live bacteria, it induces a strong delayed-type hypersensitivity (DTH) in immunized animals. Elicits a mostly Th1 type of T-cell response in healthy humans; induces IFN-gamma production from CD4(+) and CD8(+) cells. Functions as an adhesin, binds to mouse macrophages via mannose residues. Might interact via host CD209.
Subcellular Localization:
Secreted. Cell surface.
Sequence:
MHQVDPNLTRRKGRLAALAIAAMASASLVTVAVPATANADPEPAPPVPTTAASPPSTAAAPPAPATPVAPPPPAAANTPNAQPGDPNAAPPPADPNAPPPPVIAPNAPQPVRIDNPVGGFSFALPAGWVESDAAHFDYGSALLSKTTGDPPFPGQPPPVANDTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQETVSLDANGVSGSASYYEVKFSDPSKPNGQIWTGVIGSPAANAPDAGPPQRWFVVWLGTANNPVDKGAAKALAESIRPLVAPPPAPAPAPAEPAPAPAPAGEVAPTPTTPTPQRTLPA
The following text describes a protein:
Function:
Involved in SOS regulation. Inhibits RecA by preventing RecA to bind ssDNA. Can displace ssDNA from RecA.
Sequence:
MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRYAAANNLSVIGATKEDKQRISEILQETWESADDWFVSE
The following text describes a protein:
Function:
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Sequence:
MQSGLCHCVRRVAALGSVANLHHFTNLPSGFSVWTSRRWQSQSSRGQPGLQWQEGVVDPRYSSSGNMRRFNPDTVAHYVKATIQNDRREMGLGEVYDWHEFAKDAVYIPTRSGPLWVGSDDPRCAKFMRRRSKMQKTPQQKARPKPGPDPAKALEDHPLREYFTTATNLRDPLSTANNLHRAGLIREYDIKYTAAKVRYVPRPPVVSIMGHVDHGKTTLLDYLRKTNVASQEAGGITQNVGAFQVKTLGDTLVTFIDTPGHAAFTTMREVGATANDLIVLVVSAVDGVQPQTKEVIELAHKSGIPFVVACTKIDRQPRVENVKQQLRDCNVELEEDGGDTQFVPVCARDGRGVPELLEAIALQAELCEISTPEPSRCEVTVIETNGVNTTTEVAGIVRCGKVRAGQVLVAGMTYAVVRKVLDEHGQIIQEAGPSQPVVLHGFRVHPKPGSVLLQVSSESHAQKFYHFMKEVYQAEGRREDYLQLLNQEQHGMLYARKPDNNLVRTYSTQAFVLSCKAATFGMLQALMKSIYEIPRLEGISTEIKVTEVGGLRDYDVALIGSSGQPGCILLYGGCKDTNTLDVPSHVTVIRFNVLYHGLEALKETLVGALPKITKIRVTAEAECLQVFRASQAGKSGNAGGMRVTKGTIIAAHLTFRVCRKAPLVKGTAETDGVSDNEGVGDEDMLGHRVVVYEGQIKELRRFKELVPSVELGLECGVIMQDEFQFRTGDILQQYETYEEPRDVAEEYQKAELREKIMRDTAAAEALLAESTGGEDKPTEESEVKTTI
The following text describes a protein:
Function:
Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.
Subcellular Localization:
Nucleus.
Sequence:
MPIAIPAAQSSSTASPNARAPVVPPAPRNPVRLSVAARDHPQPSAGPSTASSTPVHTTSVPSGNNSIAPAGGEDAEALKRAAVRKAQLQRRVERWMDKLMEETVDRATFKKTVSHFTPPQYLEITHERHLNSLCSYPVCPNPPYRPYSSSRRFVISTRARTIKPKEGNEEEGYCSKKCRARSGWVEGKLDKEAVWLRGKVEDVELLEELEERGEVNLEAITKEEPKTTSRKESTARATPSPVPKPALPTKQIISNPKQPLASEVLVPAPSANVVTSLIESLTIHERPVPSVAPAPPSLSGPVDHSTSSHAPPAVEPQPLPLPQPQPQPSLSSHARRNPNSLLSPSSTLTRSLLSATNSIPAAAISQSSPNGDDSEEEESEASEWEKEMRFGEETEEVKGWFEEAMAAREMLGDKEETEE
The following text describes a protein:
Function:
Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MARGCLMVPRCHLLGRVGTTTEPALLQEHSRGLLRCFVSKLFLLPCNGSEWEEISGVDEEYKPIRTYQVCNVMEPNQNNWLQTGWIARRDGQRIFIELKFTLRDCNSIPGVTGTCKETFNLYYAESDADLGHSIRESKHTKIDTIAADESFTQGDLGERKMKLNTELREIGHLSKRGFHLGFQDVGACVALVSVRVYYKKCLSTVQNLADFPDTVAETAFATLVEVKGTCVEHARVDVDNPPRMHCSAEGEWLVPVGKCLCSPGFEERDGRCRACLPGFYKLSLRLPLCSPCPEHSFTHEEASTFCSCQKNYSRSPSDPLSASCTRPPSAPRDLVYSLRRSSLVLRWSAPADAGGRNDLTYSLWCSRCPAPRGGCEQCGNGVGFVPQQTGLVERTVTLVNLLPHANYTIRVVALNGVSAGSPLAGQPYAEVNVSTGLTVPTPVTDIRTDKVEQKSISLSWQEPGFPTNSTEYEVKYYEKDQRDRSYSTVKTTSTAVTVNNLKPGTLYIFQIRTSSSQDYGNYSPSIEVETLAELTVASNEQNPVLIIIVVAIAGLTVLVSMVVGMMVWRRQCGYSKASQDGDEELYFHFKIPTRRTYIDPDTCEDPMQAVHLFAKELDNASIKIERIIGTGEFGEICRGWLKLPSKRELPVAIQTLRAGCSAKQQRCFLAKACTMGQFDHANVIRLEGVITRGNTMMIVMEYMGNGVLDSFLRKHEGQLTASQLLSMLQGIAAGMKYLAEMGYIHKSLAAHKVLVNSSLACKITGFRRLQEDKMETIFSTMRGKSLVLWSAPEAIQYHHFSPASDVWSFGIVMWEVMSYGERPYWDMSHQDVMKAVEDGFRLPAPAHCQPPLHQLMLDCWQKERSQRPKFSHIHDVLSKMLQSPELSPCTRSRSTVPLTERSFAAFPAFSSVGEWLEAIGMGRYRDNFTAAGCCYLESVARMTAQDVLSLGITQAEHQKTILSGIQTLRAQVIQMHGRGVQV
The following text describes a protein:
Function:
Orphan nuclear receptor.
Subcellular Localization:
Nucleus.
Sequence:
MMKDEYNSQECMVCSAPADGLHYGAISCRSCNAFFRRTVVEKAEYRCKHTNTCLIDPDGRCACRSCRFTKCIEAGMKIGAVQPRRDPTGSQKERRKRAGGVGEMMSMNNSPLERNGNSFSSDGPTSNSFIVDAIRTDYGFATPRRISTDYSNSPDRYRKYVKIELDDEPIPSTSSAPEKQSCQSSPNDDEQQEFNHLVYAFGEHQRMMQLSFSTFEQFLDEHSNGPKLRRMDPLDVSKLSAVELTGLLYWIEKQQPYGELPVEDRSSLLKRYSVRKLSLDHFYSASKHPEYCARGEFVMNNFTFVPADRTGFELPDDDPHQIQAKREHCRTFAPTFNRFWKNVIRPFVLMKVNDAEVVFLHIMLLWSVTNNEHVTEDTRKVMKQRRDWAMNRLFDWYNEHGTSDPPLRFGQMILLLGEIELICDMHCQDFQVAKLFEFCDMSKFWYETLCYAPCNTNVLKFDPNLLENLKRFTAISVMENNGGLRPFVKTEIKQDPVLYSSPEVIAPESCYNDYQTVDIPVDCNPHTEPVSMDPNLANIDPAVLVFNAHMLPSVMAPLPDDADYHRPQLYHTQSEEVMT
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that acts as a negative regulator of the immunity triggered by the pathogen-associated molecular patterns (PAMPs), in association with PUB22 and PUB23.
Sequence:
MDQEEEEIEIPNYFICPISLEIMKDPVTTVSGITYDRQNIVKWLEKVPSCPVTKQPLPLDSDLTPNHMLRRLIQHWCVENETRGVVRISTPRVPPGKLNVVEEIKNLKKFGQEALGREETLQKLEVLAMDGNNRRLMCECGVHKSLILFVVKCTSEDEDGRRRIKGLDESLRLLHLIGIPSNDAKTILMENDRVMESLTWVLHQEDFLSKAYTIVLLRNLTEYTSSHIVERLNPEIFKGIIGFLKDVVNSVNRTSPTVRETVQSSSRPSLGKTEPSKLDHSLVIKQAVTAALMILLETSSWSRNRSLLVDLGAVSELIELEISYTGEKRITELMLGVLSRLCCCANGRAEILAHRGGIAVVTKRLLRVSPAADDRAISILTTVSKFSPENMVVEEMVNVGTVEKLCSVLGMDCGLNLKEKAKEILKDHFDEWKKFPCIDITLLTKLLSISPKGPKI
The following text describes a protein:
Function:
May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MLKTRAMFPHKDQAMSLSLDPQSDLVVGHTNNRPITNPLALSLLIGLNNKNKCISDSDFVRSPKSPLEFRVLSTMADSFFLRSPRSSLTAHLNCCCGPAAKVGLSIVDSLGDDRCLLPDIVFGPALRIKCSEVMDKHPKLLFPVANKSKKIENERSGVVFEIGDNSSETEPVGLRNRSFSANDCLRKTRVLSRSKLGQEGDFPGSGSDNAFSSEDDMEDYTCIIAHGPNPKTTHIYGDRVLECHKNELKGDEDNKEKFGSVFPSDNFLGICNFCNKKLGGGDDIYMYREKSFCSEECRSEEMMIDEEDLEEPCIDMHESLKKLF
The following text describes a protein:
Function:
Plays a role in the regulation of phosphate uptake.
Subcellular Localization:
Cytoplasm.
Sequence:
MNRLLNEKVEEFKKGVLKAGWFIEKMFRNSISSLVERNESLAREVIADEEVVDQMEVEIQEKAMEVLGLFSPIGKPLLTVTAGIRVAELIENIADKCHDIAKNVLELMEEPPLKPLEDIPAMANQTSEMLKFALRMFADVNVEKSFEVCRMDSKVDDLYEKVREELLLYMMESPKYVKRALLLLEIAGNIEIIADYATNIVEVSVYMVQGEAYKCYHDELLLFKKSGGVLFESSD
The following text describes a protein:
Function:
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
Subcellular Localization:
Nucleus.
Sequence:
MKVDEDVRMISAEAPVIFARACEIFILELTLRSWNHTEENKMRTLQKNDIATAIARTGIFDFLVDIVPREDCRSVKLQIRWERGWG
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSTANNRFPVTGKETSSFVKTCNRLSSFLKGRGSLRDLGIDEKFDAKGKSEIPSPATENNTATVDLLSNIDATVRTTTENTEKTINNNLPEYVTLDSFREPVDSTNKSGSAEPETKTGQMTIFYGGKVIVLDCVTADKARDLVLAVASGSSSSSSDIQIQNRIEVDGSDLPIARRASLHRFLAKRKDRASVRVVPYQLHNPLMAEEPLDRSKFDLNL
The following text describes a protein:
Function:
Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.
Subcellular Localization:
Secreted.
Sequence:
MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPSYAS
The following text describes a protein:
Function:
Does not appear to have detectable kinase activity.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=May be associated with vesicular structures.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MPFGCVTLGDKKDYNHPTEVSDRYDLGQLIKTEEFCEVFRAKEKSSGKLYTCKRFLKRDGRKVRKAAKNEINILKMVKHHNILQLVDVFETRKEYFIFMELASGREVFDWILDQGYYSEKDTSNVIRQVLEAVAYLHSLCVVHRNLKLENLLYFNRMKNSKIVISDFHLAKVETNSLIKEPCGTPEYLAPEVVARQRYGRPVDCWAIGVIMYILLSGNPPFYDELEEEDYESHDKNLFRKILHGDYEFDSPYWDDISPAAKDLVTRLMEVEQDQRVTAADAISHEWISGNAASDKNIKDGVCAQIEKNFAKAKWKKAVRVTTMMKRLRAPEQTDPGTPSPSKDSDKTPSMATPAPSPANTPAEGAPSLPCPSPDTTG
The following text describes a protein:
Function:
Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate; Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Subcellular Localization:
Chromosome. Nucleus. Chromosome, centromere.
Sequence:
MSSPLQRAMGDTKRALSASSSSSASLPFDDRDSNHTSEGNGDSLLADEDTDFEDSLNRNVKKRAAKRPPKTTPVAKHPKKGSRVVHRYSRKQSEPPANDLFNAVKAAKSDMQSLVDEWLDSYKQDQDAGFLELVNFFIQSCGCKGIVTPEMFKKMSNSEIIQHLTEQFNEDSGDYPLIAPGPSWKKFQGSFCEFVRTLVCQCQYSLLYDGFPMDNLISLLTGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSVHQDNNQRQYEAERNKGPGQRAPERLESLLEKRKELQEHQEEIEGMMNALFRGVFVHRYRDVLPEIRAICIEEIGCWMQSYSTSFLTDSYLKYIGWTLHDKHREVRLKCVKALKGLYGNRDLTTRLELFTSRFKDRMVSMVMDREYDVAVEAVRLLILILKNMEGVLTDADCESVYPVVYASHRGLASAAGEFLYWKLFYPECEIRMMGGREQRQSPGAQRTFFQLLLSFFVESELHDHAAYLVDSLWDCAGARLKDWEGLTSLLLEKDQNLGDVQESTLIEILVSSARQASEGHPPVGRVTGRKGLTSKERKTQADDRVKLTEHLIPLLPQLLAKFSADAEKVTPLLQLLSCFDLHIYCTGRLEKHLELFLQQLQEVVVKHAEPAVLEAGAHALYLLCNPEFTFFSRADFARSQLVDLLTDRFQQELEELLQSSFLDEDEVYNLAATLKRLSAFYNAHDLTRWELYEPCCQLLQKAVDTGEVPHQVILPALTLVYFSILWTLTHISKSDASQKQLSSLRDRMVAFCELCQSCLSDVDTEIQEQAFVLLSDLLLIFSPQMIVGGRDFLRPLVFFPEATLQSELASFLMDHVFIQPGDLGSGDSQEDHLQIERLHQRRRLLAGFCKLLLYGVLEMDAASDVFKHYNKFYNDYGDIIKETLTRARQIDRSHCSRILLLSLKQLYTELLQEHGPQGLNELPAFIEMRDLARRFALSFGPQQLQNRDLVVMLHKEGIKFSLSELPPAGSSNQPPNLAFLELLSEFSPRLFHQDKQLLLSYLEKCLQHVSQAPGRPWGPVTTYCHSLSPVENTAETSPQVLPSSKRRRVEGPAKPNREDVSSSQEESLQLNSIPPTPTLTSTAVKSRQPLWGLKEMEEEDGSELDFAQGQPVAGTERSRFLGPQYFQTPHNPSGPGLGNQLMRLSLMEEDEEEELEIQDESNEERQDTDMQASSYCSTSERGLDLLDSTELDIEDF
The following text describes a protein:
Function:
May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MEPITFTARKHLLSNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSRQSTRKEPVTKQVRLCVSPSGLRCEPEPGRSQQWDPLIYSSIFECKPQRVHKLIHNSHDPSYFACLIKEDAVHRQSICYVFKADDQTKVPEIISSIRQAGKIARQEELHCPSEFDDTFSKKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSGSRGSESPRPNPPHAAPTGSQEPVRRPMRKSFSQPGLRSLAFRKELQDGGLRSSGFFSSFEESDIENHLISGHNIVQPTDIEENRTMLFTIGQSEVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRESSGGGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQSLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKEHIHIGEMKQTSQMAAENIGSELPPSATRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSISVDLDSSLSSTLSNTSKEPSVCEKEALPISESSFKLLGSSEDLSSDSESHLPEEPAPLSPQQAFRRRANTLSHFPIECQEPPQPARGSPGVSQRKLMRYHSVSTETPHERKDFESKANHLGDSGGTPVKTRRHSWRQQIFLRVATPQKACDSSSRYEDYSELGELPPRSPLEPVCEDGPFGPPPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDIAKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLKQAMLTLELERSALLQTVEELRRRSAEPSDREPECTQPEPTGD
The following text describes a protein:
Function:
Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
Subcellular Localization:
Cytoplasm.
Sequence:
MKLTIKRVPTVVSNYQEDAGERPRGGCGRNCLGHCCLPVSELPVYAFKANPTKLPLQEDAVPTDFFINLLLGQWEDRMTQGLFRYDVTACETKVIPGNLGFVAQLNEGRHLKKRPTEFRVDRVLQPFDSAKFNFTKVGQEEVLFQFENSGSDDSYFLRSAAVTVADRAPNVVAINVSPIEYGHVLLIPRVLDHLPQRIDQESFLLALHMAAEAASPYFRLGYNSLGAFATINHLHFQAYYLTVPFPVEKAATQRIPLAEGGIKSGVKVSKLMNYPVRGLVFEKGYTLNDLANVVSSACIWLQDNNVPYNVLISDSGRKIFLFPQCYAEKQALGDVSQELLDTQVNPAVWEISGHIVLKRRDDYEEASEASAWRLLAVVSLSEARFEEVKAYIFDAACLVQSQVEEEIDDAIYAPVPVGPSAVGEGCLVIP
The following text describes a protein:
Function:
Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection (By similarity); May play a role in the aggregation of tegument proteins around nucleocapsids during virus morphogenesis.
Subcellular Localization:
Virion tegument. Host nucleus.
Sequence:
MEANMSFENDYYSPIQLFAEIEAYANTMDKSPDLDILRTIEEFDETLLSEIEVRTQSIPSPLVAPSVTKMSLPSPSPAPPNSLYTRLLHELDFVEGPSILARLEKINVDLFSCFPHNKHLYEHAKILSVSPSEVLEELSKNTWTYTALNLNEHGEMALPMPPTTKADLPSYVDDIQNFYLGELEAREKSYATMFYGYCRALAEYIRQSAIKDLRDARVEDKNIGACSKARQYIAERYYREAARFAKLLYVHLYLSTTRDVSQRLEASQMGRQNIFVYLKCEWLQERHFHCLFQPVIFNHGVVIVEGRVLTAPELRAQNYIRSEFGLPLIRCKLVEEPDMPLISPPPFSGDAPRASVYLLQCIRSKLEVYSLSHPPNPQLHVHKEHVHVQKLESPPNYGTTVEALLMDSSDRNSISPGDPVATTISTL
The following text describes a protein:
Function:
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Subcellular Localization:
Secreted.
Sequence:
MPICITKAGELTPRRARGVSSSSWSGPTQGCAYTMGRQDGGRRCVLVLLLAGICVCAEAASTRRCTTCSPHTVQDKVENALRLELIKRQILDRLGLDARPNITKAVPRKAIHTALRRLHAEDLITQVTTPAPEDHDDEQQEHHEEAQTVEIISFAEAADGDLGREYIQFKTSDNAETTVASRAVTWVFLKLYADKMAMRKPVSVTIDLAQVRSAGLGLQQVETVVRRTLLITRSGWHSFNVVGALRDVLENKVTFRVRCYGCGSVVKPMLLSDVGVSVRPDVLRRRRGEEDEGSLHHKLGHDVDLDEVKHPHHPFLVLRTRSKPGKRRSKRQADKGACRKHSLFVSFEQLGWDDWIIAPMPGYQANFCAGGCPSVQYPETTASFHALLGDEKRFDTPYSTYISPCCTPTKMSSISMLYFDKDNNIVKADVRNMVVDECGCK
The following text describes a protein:
Function:
Transcriptional regulator that regulates large-scale gene expression in response to sulfide. May act as a global regulator responsible for redox homeostasis. It functions as both a repressor and an activator. In the absence of sulfide compounds, it negatively regulates many anaerobic respiratory genes, including formate, fumarate, lactate, nitrate and nitrite reductase genes. In the presence of hydrogen sulfide (H(2)S), YgaV activity is attenuated, leading to the expression of anaerobic respiratory and ROS scavenging genes, which contributes to redox homeostasis, reactive oxygen species (ROS) scavenging and antibiotic tolerance. It responds to H(2)O(2) scavenging and increases antibiotic tolerance under H(2)S-atmospheric conditions. It also negatively regulates its own expression by binding to the ygaVP promoter region. May also be involved in regulatory mechanisms that operate independently of sulfide.
Sequence:
MTELAQLQASAEQAAALLKAMSHPKRLLILCMLSGSPGTSAGELTRITGLSASATSQHLARMRDEGLIDSQRDAQRILYSIKNEAVNAIIATLKNVYCP
The following text describes a protein:
Function:
Hydrolyzes only single-stranded DNA and RNA without apparent specificity for bases.
Sequence:
MPRLLPISAATLALAQLTYGWGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS
The following text describes a protein:
Function:
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria (By similarity).
Subcellular Localization:
Secreted. Host cell. Note=Secreted via Mxi-Spa type III secretion system (T3SS), and delivered into the host cell.
Sequence:
MKITSTIIQTPFPFENNNSHAGIVTEPILGKLIGQGSTAEIFEDVNDSSALYKKYDLIGNQYNEILEMAWQESELFNAFYGDEASVVIQYGGDVYLRMLRVPGTPLSDIDTADIPDNIESLYLQLICKLNELSIIHYDLNTGNMLYDKESESLFPIDFRNIYAEYYAATKKDKEIIDRRLQMRTNDFYSLLNRKYL
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). Binds directly to 7SL RNA (By similarity). Mediates binding of srp54 to the SRP complex (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MTSAQPKAVDVSTIPGFKKWYIVYPNHINSELTKEKGRKVSKEHGVKNPTLPEIAEATAQLGLPCIIETSKGYPKEFFLRGRLRINFFCDGTTMPRNPHIPNKTVLLVKIAERIKLINPNRPEPFNPISMLAPIQAVSQKEKKPAPQPTTTTTTTTTPSSSSSSSSKGGKKKKNVNVI
The following text describes a protein:
Function:
Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
Sequence:
MLSRLQDFLSRHRRKFIVTGVLVGGTIFAARYAQRRFVEFQEKQAREFFERTRRTTHFESTEKTCNQVILGMGEEMCQAVLRECSTDELLEQLRQNPKNKLELWEDMKIVAFTRLATYVYASSMLVIALRVQLNLLGGYIYRDIMTEQKQVTDELKQQYLSLIRHFITDSGIRDLARYIRTQVIAVTKTIPLSEQLSLSDLEQLFWSLQMAINADTRRDPNSRMSKYLLPSQNPSHSPLLQKMVNETLDLLESEDAVGVCSHNVSRGFVLACDAIAESMGETLQHLPQAKVQTQQEQSVKFNQAGSLGASTSKSQNGLENNNLLNINRVLLALAKLIPIISGLTSRGFDTTSRPHNLPTQLLTFYVVAEKTKTLGANVYESFSSA
The following text describes a protein:
Function:
Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center.
Sequence:
MVLIQEMIVIDDLLSALTGIDGRYISIKKSGGGEDAFSFHVDGSMDLALQARMFTYVESAKRIFPLCKSYLLINQFVESRSQFKSGLVNHAFAAALRALLLDYQAMVAQLEHQFRLGRLSIQGLWFYCQPMMGSMQALSIVIKKASAYNFVGSAVLNLLQSQAKLMAGNYLVRSLLEKMIDSANSAYLGILERWVYEGVIDDLHDEFFIAENKSLQKESLTQDYDAMYWRQRYSLKDDIPSFLANSAETILTTGKYLNVMRECGHTVQVPALENSKLTSFGSNDHYLECIKSAYDFASGELLNLMKDKYDLNGKLRSIKHYLLLDQGDFLVHFMDIARDELAKTPNEISVEKLQSLLDIALRSTAAAADPLHEDVTCSVDSCSLLKRLSTLKDLQTGETVAETEEPLSVTGVETFSVNYKVKWPLSLVISRKALTKYQLIFRFLFHCKHVHRQLCAAWEVHQGARARDRHGTAISTSSILCRNMLKFINSLLHYLTFEVLEPNWHVMHNKLENAKSIDEVIQYHDFFMEKCLKECSLLSPILLKLEKLKLVCLQYAAATQWLMNSIEVPEDTDNPSYESCKVLLKLRKPSKKPNSPTQESSVIQCVLKFEREFTSELQSLRPILSSRAQAEPYLTHLAQLILGVGMDQQM
The following text describes a protein:
Function:
Binds and stabilizes pmp1 mRNA and hence acts as a negative regulator of pmk1 signaling. Overexpression suppresses the Cl(-) sensitivity of calcineurin deletion.
Subcellular Localization:
Cytoplasm.
Sequence:
MAYNHFSIPKNIEEKENSFFDVTFQDEPDETTSTATGIAKVSIPTPKPSTPLSTLTNGSTIQQSMTNQPEPTSQVPPISAKPPMDDATYATQQLTLRALLSTREAGIIIGKAGKNVAELRSTTNVKAGVTKAVPNVHDRVLTISGPLENVVRAYRFIIDIFAKNSTNPDGTPSDANTPRKLRLLIAHSLMGSIIGRNGLRIKLIQDKCSCRMIASKDMLPQSTERTVEIHGTVDNLHAAIWEIGKCLIDDWERGAGTVFYNPVSRLTQPLPSLASTASPQQVSPPAAPSTTSGEAIPENFVSYGAQVFPATQMPFLQQPKVTQNISIPADMVGCIIGRGGSKISEIRRTSGSKISIAKEPHDETGERMFTITGTHEENEKALFLLYQQLEMEKDRRSH
The following text describes a protein:
Function:
Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Required for localization of CUL7 to the centrosome.
Miscellaneous:
MISCELLANEOUS: Despite its name, does not contain a coiled coil domain.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Domain:
The PxLPxI/L motif mediates interaction with ankyrin repeats of ANKRA2.
Sequence:
MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAVFRERLIQFLQEEGRTLEDVARIIEKSTPHPPQPPKKAKVPRVRRVPQMVTPPLRLVVGTYDSSNGSDSELSDFDTSKVKGNRGSGKTRKVRKMPVSYLGSKFLGSDESEDDQELVEAFLRRGEKKPSAPPPRRRVNLPVPMFENNLGPQPSKGDRWREYVSQVSWGKLKQRVRGWAPRSGSEVGQAQQSSIAERAGEMRHSHTSPDLDDSSRNTGDLSDQTLITRRWKPKIKWVSLRRCRKEQVPPLAHGTAEEPPEAAENQGAGAAAEHGVEAAASQRPEAAASPRAEAAANPRAEATANPRAEAAANPRAEAAASPRAEAAANPRAEAAANPRAEATANPRAEAAANPRAEATANPRAEAAVNPRTEAAVNPRTEAAANPRAEAAVNPRAEATASPRAEAEVNQKTEATASPRAETAASPRVEAAASLRVEAAASPRAEATVSPRAEAVATPRAETAASARVEAAANLRAGVLPDQRAEAIDSQRAEGPVNQSTGATENQRVEVLADQRAGVLHDQREEAGPQAILEASADSGSRARKQVKTVRFQTPGRFSWFHMRRKAFWHTPRLPTLPKRGPRAGAGEARSLRVLRADTRADMEHREQEEQL
The following text describes a protein:
Function:
May function in gibberellin signaling pathway downstream of GID1 and SLR1. May be involved in the regulation of plant growth in the basal region of leaf sheaths (Probable). Involved in tolerance to aluminum. Regulates the expression of different genes that collectively contribute to the protection of the cell in response to aluminum stress. Binds to the promoter and regulates the expression of target genes involved in aluminum stress response. Binds to the promoter of STAR1 gene, which encodes an ABC transporter required for aluminum tolerance. Involved in drought tolerance. Plays a positive role in response to drought stress response by regulating abscisic acid (ABA) biosynthesis, promoting stomatal closure, and acting as chaperone-like protein that possibly prevents drought stress-related proteins from inactivation.
Miscellaneous:
MISCELLANEOUS: Plants silencing ASR5 exhibit delayed flowering, abnormal panicles, reduced seed number, reduced number of trichomes on leaves, palea and lemma, and exhibit sensitivity to aluminum and drought stress. Plants over-expressing ASR5 exhibit enhanced tolerance to salt stress, osmotic shock and drought stress.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MAEEKHHHHLFHHKKDDEPATGVDSYGEGVYTSETVTTEVVAGGQDEYERYKKEEKQHKHKQHLGEAGALAAGAFALYEKHEAKKDPENAHRHKITEEIAATAAVGAGGYAFHEHHEKKKDHKSAEESTGEKKHHLFG
The following text describes a protein:
Function:
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell. Expression of this specific KDG-uptake system may allow growth with KDG as the sole carbon source. Can also transport D-glucuronate.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGTAGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK