lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Regulatory subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1, modulates the kinetics parameters of the heterotetrameric channel namely the inactivation and deactivation rate. Potassium channel subunit that does not form functional channels by itself. Reduces the deactivation rate. Moderately acceleratee activation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Colocalizes with KCNB1 at the plasma membrane. Retains in the endoplasmic reticulum in the absence of KCNB1.
Domain:
The transmembrane segment S4 functions as a voltage-sensor and is characterized by a series of positively charged amino acids at every third position. Channel opening and closing is effected by a conformation change that affects the position and orientation of the voltage-sensor paddle formed by S3 and S4 within the membrane. A transmembrane electric field that is positive inside would push the positively charged S4 segment outwards, thereby opening the pore, while a field that is negative inside would pull the S4 segment inwards and close the pore. Changes in the position and orientation of S4 are then transmitted to the activation gate formed by the inner helix bundle via the S4-S5 linker region.
Sequence:
MTFGRGGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTHTFHAADELGREQPRPAGPEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDWRAAVADNRSLDDRSRYSASPGREPSGIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMAMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFASIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLSAEFLN
The following text describes a protein:
Function:
Potent vasoconstrictor.
Subcellular Localization:
Secreted.
Sequence:
MKFFSTSLCFGLLALLSVTTLLHSVRGRPHLSSGHELFPAEEHTTQEKLPLGLLIRNPGFQRPAHAGVDLPSKVEELRQLKKLREWFMEAKSAEPSNALDKLSSSHPIKRACFWKYCV
The following text describes a protein:
Function:
EsxG, in complex with EsxH, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery. EsxG stabilizes EsxH in the host cytosol.
Miscellaneous:
MISCELLANEOUS: To improve expression in E.coli the proteins were cloned as a single protein in the order esxH-esxG with a cleavable thrombin tag.
Subcellular Localization:
Secreted. Note=Secreted via the ESX-3 / type VII secretion system (T7SS).
Sequence:
MSLLDAHIPQLVASQSAFAAKAGLMRHTIGQAEQAAMSAQAFHQGESSAAFQAAHARFVAAAAKVNTLLDVAQANLGEAAGTYVAADAAAASTYTGF
The following text describes a protein:
Function:
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MYVRHLGLRDFRSWACVDLELHPGRTVFVGPNGYGKTNLIEALWYSTTLGSHRVSADLPLIRVGTDRAVISTIVVNDGRECAVDLEIATGRVNKARLNRSSVRSTRDVVGVLRAVLFAPEDLGLVRGDPADRRRYLDDLAIVRRPAIAAVRAEYERVLRQRTALLKSVPGARYRGDRGVFDTLEVWDSRLAEHGAELVAARIDLVNQLAPEVKKAYQLLAPESRSASIGYRASMDVTGPSEQSDIDRQLLAARLLAALAARRDAELERGVCLVGPHRDDLILRLGDQPAKGFASHGEAWSLAVALRLAAYQLLRVDGGEPVLLLDDVFAELDVMRRRALATAAESAEQVLVTAAVLEDIPAGWDARRVHIDVRADDTGSMSVVLP
The following text describes a protein:
Function:
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated somatic hypermutation (SHM) and class-switch recombination (CSR), 2 processes resulting in the production of high-affinity, mutated isotype-switched antibodies.
Subcellular Localization:
Nucleus.
Sequence:
MGKLLSYQPNRGIKRPRDGKEEEQKMHRKQTSTQDWEEEMIVVEEAEDDKNLLLQIIDTEGEEEEKEEEPLDESSVKKMILIKFPDNPEKFMESQLDLHDIIQKMHVVATMPDLYLLLELNAVQSLLGLLGHNNTDVSIAGVDLSQELTDIDIFYESGEGAEVLIDALVDGQVIALLVQNVERLDESVKEQVKGVHNTLVIVENMLEMCTKGAQQGLPQWLLKRLKAKKPFDANKLYCSEMQAILLQDNDESRKLLGELDRIDALLQQLSVFKRHNPSTHFLKGEGLQVMNLMLREKKISQSRVLKVLIAPEGIYNCGKFVDILVGTTDKEHKQHVCSILASLLWNLRGHQLMELHFQYLGAMQVADKRNEGEKHDMVQGGEIIDSDMGDEFYLQCLDAELFVLQCICCIMSKICNANVPQICQRVHQILNMHIIKGYAEFREKEQKHILGLLENF
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity). By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MKKGIAKIFCVIGISIFLHTVYSALQHRKYLRLTDQPFEGVPFDIVVECIISLFLFAWGIINSQFLIPIKASTHLAKKSFDSYDYRPNFTVFNHRGKYLNEILNK
The following text describes a protein:
Function:
May play a role in the trafficking of a subset of G-protein coupled receptors.
Subcellular Localization:
Membrane.
Sequence:
MGRTYIVEETVGQYLSNINLQGKAFVSGLLIGQCSSQKDYVILATRTPPKEEQSENLKHPKAKLDNLDEEWATEHACQVSRMLPGGLLVLGVFIITTLELANDFQNALRRLMFAVEKSINRKRLWNFTEEEVSERVTLHICASTKKIFCRTYDIHDPKSSARPADWKYQSGLSSSWLSLECTVHINIHIPLSATSVSYTLEKNTKNGLTRWAKEIENGVYLINGQVKDEDCDLLEGHKKSSRGNTQATSHSFDVRVLTQLLLNSDHRSTATVQICSGSVNLKGAVKCRAYIHSSKPKVKDAVQAVKRDILNTVADRCEILFEDLLLNEIPEKKDSEKEFHVLPYRVFVPLPGSTVMLCDYKFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASLDNTDDEQPKQPIKTTMLLKIQQNIGVIAAFTVAVLAAGISFHYFSD
The following text describes a protein:
Function:
Plays a role in protein import into the endoplasmic reticulum (ER). May function as chaperone docking protein during post-translational protein translocation into the ER. Chaperone receptor mediating Hsp70-dependent protein targeting to chloroplasts. Interacts specifically with some chloroplast precursors, but not with mitochondrial precursors. Able to select precursors for delivery to the chloroplast translocase independently of Hsp70.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Plastid, chloroplast outer membrane; Single-pass membrane protein. Note=Resides most likely exclusively in the ER membrane.
Domain:
The TPR region (103-213) is necessary for interaction with HSP70-1 while the linker domain (214-530) facilitates selective recognition of chloroplast precursor complexes.
Sequence:
MFNGLMDPEMIRLAQDQMSRMTPADFARIQQQMMSNPDLMNMATESMKNMRPEDLKQAAEQLKHTRPEDMAEISEKMAKASPEDIAAMRAHADAQFTYQINAAQMLKKQGNELHSRGNFSDAAEKYLRAKNNLKEIPSSKGGAILLACSLNLMSCYLKTNQHEECIKEGSEVLGYDARNVKALYRRGQAYRDLGLFEDAVSDLSKAHEVSPEDETIADVLRDVKERLAVEGPGKASRGVVIEDITEENNVTSGENKKPSKEANGHAQGVKTDVDGLQALRDNPEAIRTFQNFISKTDPDTLAALSGGKAGDMSPDMFKTASSMIGKMSPEEIQKMVQTASSFKGDNPFAPTAPSTENGFTPTPDMLKLASDMMGKMSPEERERMFNMASSLKANAPASTSYGNAEASEPRESLGASGSSSGNSFVAPRSGFEPSIPSAPPADLQEQMRNQMKDPAMRQMFTSMIKNMNPEMMASMSEQFGMKLSQEDAAKAQQAMASLSPDALEKMMRWADRAQTGMEKAKKAKKWLFGKGGLIFAILMLVLAMVLHRLGYIGN
The following text describes a protein:
Function:
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNDYLANELVLKLGVHQYAHITNDNDNGTVLITGPMTRTLGSDERLTKPITPFHVVPHGHYCCIENPHEVAEDGVTPVCDKSGQVKVSLGKRKIFVGPLAVPLYPEEKLVSVEPLTVLDTNSALLVRVIHDYTSEGGVRRSQGERYLFKGPGTYFPRVEETPLEVRHAVNIKKGCAIRLRALELFTDRTGRTRKRDDEYLYLTPGSYLCDVDEQFVEHVEPLIIPPDEALHVEVLRNFVDERPNAFNRARHAGEVYVVTHEDCPMFVPHPNEKILRTVHKMRLTDKQYAVIVNASKSRRRTITNVSYYLQVDEEVENDAIHGCYLLGEGQALLLRALDMFQDESVEPPVQRVAEDLWLLHGPREYVPHSLVEVCKDKNGNDIRERILLCDGDGIYVRDKTTGVVRTVTGPAAYMLGVHEELWEKSLPPDVEGCLQRQLSPMEGHIAAGQGPVLVPRNLVRSAYKTVVYKVPHRSVTQLYNYRTMKTRTIFGPDRVTLEPDEEFTVVKLSLPSSDGTSPAKCQSKESSRVNALHLFLGPSNVTDIVHVETRDHAQLALQLCYAWHFDVAHGDEAAARKCFGVDDFIADACSLIAGRIRAAVASLPFQQFHKSSVKVLQQAVFGINPVNGDPMSELRFDANNFVVTSVDTHTMEVLDPRTREGLQKSVKIAIEMSTQAQESSAQQVALAREQQSSALLAQQKMKDQVENETQRKALLEAEAKSAATISSGRFRSAADSAAKAASVEEETNLKCTRVRMKSEDIMNGALCEIEQNRRTQEHQYEAARASLEREFKRELSKIENDKFAAVMSALGPDTVEEIAKAGPELQAKLLESLGLQGYLVMDGSTPINLFNTASELTGHVQQ
The following text describes a protein:
Function:
May contribute to coordination of muscle contraction as regulatory subunit of the nonessential sup-9 potassium channel complex. May act downstream of sup-10.
Subcellular Localization:
Membrane; Single-pass membrane protein. Note=In body-wall muscle cells, localizes to dense body-like structures which connect the myofibril lattice to the cell membrane. Colocalizes with sup-10. Membrane localization is not essential for its activity.
Sequence:
MKKHTHHKAYGDSTGKEPLIDLQSIKLWLNSFGNQGHSSEAVLNVLFTLGVILFVIYQVASLLHRMNKRVEKQLESRTKQRKVEVADKHVGDEMVFTDLHENVIRERMIPYRMPVINDDITLRNSQIFYEEMKMRRSCRQFSSRDVPLKVIQNLLKTAGTSPSVGNLQPWTFCVVSSDSIKTMIRKILEADERDNYVSRKKGASWVVDVSQLQDTWRRPYITDAPYLLIVCHEIFRDVHSKTERVFHYNQISTSIAVGILLAAIQNVGLSTVVTSPLNAGPDISRILRRPENESILLLLPLGYASEDVLVPDLKRKPVEHITKLY
The following text describes a protein:
Function:
Required for haploid cells axial budding pattern. Acts as an anchor to help direct new growth components and/or polarity establishment components like the BUD5 GTP/GDP exchange factor to localize at the cortical axial budding site. Regulates septin organization in late G1 independently of its role in polarity-axis determination.
Miscellaneous:
MISCELLANEOUS: Present with 396 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Note=In small buds, localizes to incipient bud sites, emerging buds and to the bud periphery. In large buds, localizes as a ring at the bud neck. Requires ERV14 to be efficiently delivered to the cell surface. Recruitment to the bud neck after S/G2 phase of the cell cycle depends on BUD3 and BUD4.
Sequence:
MTQLQISLLLTATISLLHLVVATPYEAYPIGKQYPPVARVNESFTFQISNDTYKSSVDKTAQITYNCFDLPSWLSFDSSSRTFSGEPSSDLLSDANTTLYFNVILEGTDSADSTSLNNTYQFVVTNRPSISLSSDFNLLALLKNYGYTNGKNALKLDPNEVFNVTFDRSMFTNEESIVSYYGRSQLYNAPLPNWLFFDSGELKFTGTAPVINSAIAPETSYSFVIIATDIEGFSAVEVEFELVIGAHQLTTSIQNSLIINVTDTGNVSYDLPLNYVYLDDDPISSDKLGSINLLDAPDWVALDNATISGSVPDELLGKNSNPANFSVSIYDTYGDVIYFNFEVVSTTDLFAISSLPNINATRGEWFSYYFLPSQFTDYVNTNVSLEFTNSSQDHDWVKFQSSNLTLAGEVPKNFDKLSLGLKANQGSQSQELYFNIIGMDSKITHSNHSANATSTRSSHHSTSTSSYTSSTYTAKISSTSAAATSSAPAALPAANKTSSHNKKAVAIACGVAIPLGVILVALICFLIFWRRRRENPDDENLPHAISGPDLNNPANKPNQENATPLNNPFDDDASSYDDTSIARRLAALNTLKLDNHSATESDISSVDEKRDSLSGMNTYNDQFQSQSKEELLAKPPVQPPESPFFDPQNRSSSVYMDSEPAVNKSWRYTGNLSPVSDIVRDSYGSQKTVDTEKLFDLEAPEKEKRTSRDVTMSSLDPWNSNISPSPVRKSVTPSPYNVTKHRNRHLQNIQDSQSGKNGITPTTMSTSSSDDFVPVKDGENFCWVHSMEPDRRPSKKRLVDFSNKSNVNVGQVKDIHGRIPEML
The following text describes a protein:
Function:
Together with ABI5, PYL5 and SAPK2, is part of an abscisic acid (ABA) signaling unit that modulates seed germination and early seedling growth.
Subcellular Localization:
Nucleus.
Sequence:
MAEICCEVVAGSSSEGKGPECDTGSRAARRRRMEIRRLRVVAERGAEEETSGKRRRLDGGGGEASTDEEDREVERARYGFTSVCGRRRDMEDSVSACPGFLPGHHFFGVFDGHGCSHVATSCGQRMHEIVVDEAGAAAGSAGLDEEARWRGVMERSFARMDAEAVASSRGSVAPAPTCRCEMQLPKCDHVGSTAVVAVLGPRHVVVANCGDSRAVLCRGGAAIPLSCDHKPDRPDELERIHAAGGRVIFWDGARVFGMLAMSRAIGDSYLKPYVICDPEVRVMERKDGEDEFLILASDGLWDVVSNEVACNVVRACLRSSGRRERNRSSPTSNLSPRQSSSSGDEAPNDGAPSAAAGSESDEESAAEEDKACAEAAVLLTKLALARQTSDNVSVVVVNLRRRKL
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MNNISTDVDKNIKTDVIEDIRTIGKFLSIIPPPNTVVDTRKDLPEAPISTINRVIAFVEKEVTVKLYHEKNNNGGDGGDLSSLLLALEQVSKLTTALGEFPSNSSYGRAIIHTVSVLQRTMAVLEEEFRLLLEEVGDDKDSSSEILEGDVLERLKKIANIMIAAGYDTDCCQVFSIVRRGKIEATLMEIGFGKIQPEELQNMAWDVLESEIASWIMAFKHMVSVSFPTERDLCEKVFSDHYSTVSDGLFSNLVRGVVIKLLNFTEHVTMTKRSEEKLFKFLDMYETMRDLTPTLNKLFSGHGKQHDQKEKEEEEEEEDGSLPSTELKCEMSAAKIHIGKPIIGMFTDLENSIKCDNGRIPVPGGAVHPLTRYVMNYLKYALEYKNTLEQVFKERHESESSDVGDYRQSTPVSFSEQVMAIMNLLDTSLDRNSNLYKDPSLSYIFLMNNGRYIVQKIKSWSEIKELLGENWCRKKSSELRQYHKNYQRETWGKVLNCFKEEGLRLKGTSSSTGAVSKSALRERFKLFNSIFEDIYKTQSTWILSDEQLQSELRVSVQAVVVPAYRSFLGRFRQYIESGKHPERYIKFAPEDLENCIDGLFDGTSSSIVRGRK
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
Sequence:
MADGDTTMRDEEDMAALLESTGRYRVLRRLAPRAAYHAPDGTPTRRAVFIDLETTGLDPVADEIVEIAMVPFDYSDDGRIFAVHESFARFRDPGRPIPPEVSAMTGITDAMVAGAAIEPAEIEAFLGDTAALVVAHNCSFDRRFAERFCPAFAHLPWACSWAEIPWREEGFVDGTKLVHLAAACGFFHEGHRAVHDCLAGIELLSRPLPRSGQRALAVLLSSARAPRWRVRAAGAPFELRESLKRRGYRWDPGEHGGQRAWFVDLPESDLEVESDFLRREIYRRDDLEVEARRLDAYDRYSDRS
The following text describes a protein:
Function:
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.
Sequence:
MEEMPPDDYSEGGRDRHVRDVTAPNFPNPSSGPVFVKFPSSTTVSPITPSSSPTGIDCHSLAPTPPSTQNRLNNNNNNNNNKMMMASLDFKTRRPSVHNARPNPTPLLTPCSSSDSLSLSSNGFNNTRHSTPAILTKIFPNGIPDVEAVHDISTQLPNALKGAIVDRDSGIRSLYILGLTSSVTIDRQVRDIVVRVLDLADEEIEADQVFFALEKDHPMFRELLQGLLYVGGNVVKNAQHQPVNKHLVLVGIEI
The following text describes a protein:
Function:
Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways. That causes phosphorylation of IL6ST tyrosine residues which in turn activates STAT3. In parallel, the IL6 signaling pathway induces the expression of two cytokine receptor signaling inhibitors, SOCS1 and SOCS3, which inhibit JAK and terminate the activity of the IL6 signaling pathway as a negative feedback loop (By similarity). Also activates the yes-associated protein 1 (YAP) and NOTCH pathways to control inflammation-induced epithelial regeneration, independently of STAT3 (By similarity). Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL27RA/WSX1 and CNTFR. Mediates signals which regulate immune response, hematopoiesis, pain control and bone metabolism (By similarity). Has a role in embryonic development (By similarity). Essential for survival of motor and sensory neurons and for differentiation of astrocytes (By similarity). Required for expression of TRPA1 in nociceptive neurons (By similarity). Required for the maintenance of PTH1R expression in the osteoblast lineage and for the stimulation of PTH-induced osteoblast differentiation (By similarity). Required for normal trabecular bone mass and cortical bone composition (By similarity); [Isoform 2]: Binds to the soluble IL6:sIL6R complex (hyper-IL6), thereby blocking IL6 trans-signaling. Inhibits sIL6R-dependent acute phase response. Also blocks IL11 cluster signaling through IL11R.
Subcellular Localization:
[Isoform 1]: Cell membrane; Single-pass type I membrane protein; [Isoform 2]: Secreted.
Domain:
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding; The box 1 motif is required for JAK interaction and/or activation.
Sequence:
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ
The following text describes a protein:
Function:
Receptor for the attractant L-aspartate and related amino and dicarboxylic acids. Tar also mediates taxis to the attractant maltose via an interaction with the periplasmic maltose binding protein. Tar mediates taxis away from the repellents cobalt and nickel; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Note=Found predominantly at cell poles.
Sequence:
MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNAMGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MYLGWYLLTFFFFLTSVKIVLVHANHNHHHHHHHEQRNNKQIANKTSHSSSGTIIVDLSGNGDFSTIQSAIDSISSDNKNWVYIYVKAGTYREKVKISFDKPFIVLEGEGQKNTFVEWDDHDSSAESPTFTTMADNVVVKSISFRTLCGMNKEDITSSLVQFKDCTISAIDANLGPGIIGFITAQGRTDPNDSNGFVFKQCNIIGNGTTYLGRPWRGYARVIFYNTKMSNIIQPLGWQPWGFAGQEDHITFAEYGNSGPGSDTSKRVSWLKNLDSSTVSKMASTSFIGTDGWLKTLTQL
The following text describes a protein:
Function:
Cytokinin receptor related to bacterial two-component regulators. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MGVGGGGGGGGEAAAVSAPAPAEEAGKDAEDGSGWTLKAKLIAVAVLVWVLGALALGVFLHSYFRHAALRKAEEGLVSMCEERARMLQDQFAVSVNHVHALAILVATFHYEKRPPALDQNTFADYTARTSFERPLLSGVAYAQRVVHGDRESFERQQGWIIKTMKHEPSPVQDEYAPVVYSQETVSYIEGLDMMSGEEDRENILRSRASGKAVLTRPFRLMSNHLGVVLTFPVYHVDLSSDAKEEDRVAATAGYLGGSFDVESLVENLLRQLAGNQELVVNVYDVTNSSNPLVMYGSEVSLGNPSPSHICMLDFGDPFRKHHMVCRYRNKPQLPWSAISSSSGVFVICMLVGYIVGAAWSRYDNVKEDCRKMEELKKQAEAADVAKSQFLATVSHEIRTPMNGVLGMLDMLLDTDLTSTQRDFAQTAQVCGKALISLINEVLDRAKIEAGKLDLESVPFDLRSILDDVISLFSSKSREKGIELAVYVSERVPELLLGDPGRFRQIITNLVGNSIKFTERGHIFVQVHLADHSNLATEPKVESVANGMNGHKDEKTAVATSVSLNTLSGFEAADSRNSWENFKLLLSYEKNEMPYESVSDKVTLVVSVEDTGIGIPLDAQAKVFTPFMQADSSTSRTYGGTGIGLSISKCLVELMGGQINFVSRPHVGSTFTFTAALQRCDRSAIGDSKPVMLHPLPSSFKGLSALLVDRRPVRATVTKYHLQRLGIACDVVATIELALGVLSGRNGSSLTSTKQPCMLLIESDSWGFKIDVPLRSRLLEMKQNGPPGLPKTILLAAAESGKLKAHYAVDSVITKPLKASGLAACLFQTLGITQSSNERRDNSGSLHGLLLGKNILVVDDNKVNLRVAAGTLKKFGAKVECVESGKDALASLQVPHKFHLCLMDIQMPEMDGFEATKQIRAMEAKANEQAVACDDSETDGATRAARWHLPVLAMTADVIQATHEECTKYGMDGYVTKPFEEKQLFQALQKFLDPGMSS
The following text describes a protein:
Function:
Involved in the remodeling of the N-acetyl-glucosamine residues of proteoglycan complexes during reproductive development. Is essential to promote the first divisions of the zygote.
Sequence:
MHSIKLVLLVLLIISFHSQTVSKHHPTIDGLLDRLDSLLPTSSVQESAAKGLLQRLLPTHSQSFELRIISKDACGGTSCFVIENYDGPGRIGPEILIKGTTGVEIASGLHWYLKYKCNAHVSWDKTGGIQVASVPQPGHLPRIDSKRIFIRRPVPWNYYQNVVTSSYSYVWWGWERWEREIDWMALQGINLPLAFTGQEAIWQKVFKRFNISKEDLDDYFGGPAFLAWARMGNLHAWGGPLSKNWLDDQLLLQKQILSRMLKFGMTPVLPSFSGNVPSALRKIYPEANITRLDNWNTVDGDSRWCCTYLLNPSDPLFIEIGEAFIKQQTEEYGEITNIYNCDTFNENTPPTSEPEYISSLGAAVYKAMSKGNKNAVWLMQGWLFSSDSKFWKPPQLKALLHSVPFGKMIVLDLYAEVKPIWNKSAQFYGTPYIWCMLHNFGGNIEMYGALDSISSGPVDARVSKNSTMVGVGMCMEGIEQNPVVYELTSEMAFRDEKVDVQKWLKSYARRRYMKENHQIEAAWEILYHTVYNCTDGIADHNTDFIVKLPDWDPSSSVQDDLKQKDSYMISTGPYETKRRVLFQDKTADLPKAHLWYSTKEVIQALKLFLEAGDDLSRSLTYRYDMVDLTRQVLSKLANQVYTEAVTAFVKKDIGSLGQLSEKFLELIKDMDVLLASDDNCLLGTWLESAKKLAKNGDERKQYEWNARTQVTMWYDSNDVNQSKLHDYANKFWSGLLEDYYLPRARLYFNEMLKSLRDKKIFKVEKWRREWIMMSHKWQQSSSEVYPVKAKGDALAISRHLLSKYFP
The following text describes a protein:
Function:
Probable transcriptional regulator.
Subcellular Localization:
Nucleus.
Sequence:
MNHRIEDITSNPSSPSPNSPFSSPQVSLQPSIIQNGLNSNNSLLNGNNFNLNGNITSSPSTSSSPPISTTTTTTTTTTTTATAKKTNSKEKKKTTNKDNNNNNNNNNSNNQQQQQQQQQQQQQQQQQQQYEEEDDDEEDEGGDDNTKVGKGEKMKARRTNQNIASRNYRQRKKVYIKEMEDKINSLTLENDSLKKDLYKIGNNPLELLKFSQEVVFLMTQIRRLVFQIDQALRNSEPDSSIKSLLNTWQSTMDQASSINEREIERFVHPYTQAKLTVMGYKPHTNPWTDFIKTPGQEDWWTKYAEKANLSSDQLEQINNLWLRFDEEERVLQKELTDLDEYIKKFFLTKIIIMPDTEKLNDIISSCLPIPENHDGDILQTSEVLEFIYNLEKLKQKFIKVQRLTWDTSKQMSKYLTVRQEAFLLVLVHSNTKYIHTNMDMTNNLWNQLNHSALSKTPSTYLLGGVHSSSSSSSSSSSSMSSSTSRILNNHGIPTPLSSSNSSPSSLSASSSIGESIHSYSQLPNVVQPIQTQPSSMFTPLPGAKPLKNQQPIDDLFFGTIPLSQVPLSFQQNSNMALFSNYRNFTQQQAQQQQQQQQQQHAQQHAQQQAQQQAHLQAQIQAQIMQQAQQIHQVQQAQQASQQAAQQAAQQAAAQQAAQQQAAQQQSPIQTQLSPPQHITPQHTPQQHIQQQQQHQNYQGTEPHLLGEFMFFNSIDATNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSTPIDQLNEYRPDYNNNNTNKILPNIIQSLSASSNNSLFSHQHQQQNSQSPTLPPSQNDSVQFHFYQPIHQNNQNNQNHNN
The following text describes a protein:
Function:
Recruits the capping protein complex to actin patches and the actomyosin contractile ring, and/or stabilizes their interaction. May serve as an adapter to link INP52 and INP53 to the cortical actin cytoskeleton. Binds F-actin.
Miscellaneous:
MISCELLANEOUS: Present with 704 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytoskeleton, actin patch. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Note=Localizes to the actomyosin contractile ring. Peripheral membrane protein in a PtdIns(4)P and PtdIns(4,5)P2 manner.
Sequence:
MTKYERDPELVNFLSKVEDLNSKRYSNIPSSKPAGEALSPVRSHNSGEYRRADMMTGKNVEGCDNLAYRSAYNYEMTFSPKKTHYSLSELNLERITPRPDLEGSASQKEKKFLISEEDYLLLQKLKASQTYNDSNADKNLPSFEKGPRMPSRGRPRPREKEIITIQYDFELPGRADIPSSSSSSSPPPLPTRRDHIKITDGNEEKPLLPTRPNKAEVTESPSSRSIKPDAVVPERVKPAPPVSRSTKPASFLSSLEDNKLTKAKSYNSEMETPKTTVKSSHIDYLDSIQLKPTTLSPTMKNKPKPTPPSPPAKRIPRSESFIKSMLNSNLTTTSKPSLPEKPQKLRNANLAAHKTKPSIPPKKVELNIVLPELRPVETSPTKQNFENSIDLPKLRSSNRNIKKEEEDSIPEAIKGIQNLKKTKQQKPAIPQKKSFLTNNSKNTTLKNGDDINKLNDEIEALSLRNNLKKRPPTAPQRKISLPEALRKVELMKKSKTEPVLESSNELSINAKLDAIIASRNLRASNTLPELSGVNTNIATSDKYTTSRDETVKETKPLVHPNKNRTRGPRRKLPTRV
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MAHESQHIDQANNFAWYFANSQFYDASSLNQAVFSSHQADPAKFETLHNRRDFERAVQNIKHGLQFMVAGEPQGEGQPWLLQRQHKVPNAEDEVETHVEGNYYNQGFYIRQAPSVLDVLAISTRLQQVAELSQNMTHWTPATGYSYYPPSYDSSKPTETASRIGSPTLAPMDLDQPEGTTTAAQPSEPAESTTEFSDALFMQSLMLTNRYGDEYMDENPLKGEPGAFVFTNTKNAVGERNKAQEQAASQPAAAAAAAAASRVDTRPPSVAPSVAATPRGAPTPVPEAHSRKGSTANVPKDKKRERRKSKGLASPTTPGVPPTG