lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (By similarity). By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes. Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways.
Subcellular Localization:
[Isoform 2]: Secreted; [Isoform 1]: Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MVAAGAGVTRLLVLLLMVAAAPSRARGSGCRVGASARGTGADGREAEGCGTVALLLEHSFELGDGANFQKRGLLLWNQQDGTLSATQRQLSEEERGRLRDVAAVNGLYRVRVPRRPGTLDGSEAGGHVSSFVPACSLVESHLSDQLTLHVDVAGNVVGLSVVVYPGGCRGSEVEDEDLELFNTSVQLRPPSTAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWMYIIPVVLFLMMSGAPDAGGQGGGGGGGSSR
The following text describes a protein:
Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular Localization:
Endomembrane system. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Sequence:
MFAFLLMCWTRSCRIMDVTADSLDEGALRNVLLTSVTLLLAFHLWLWIRRRPTPRLPGPFAWPLIGNAAQLGNAPHLYFMRMVKKYGTVFQIQLGSRAVVVLNGDSIRQALVKQGPDFAGRPDFTSFRFIANGDSLAFNTVSDWWKTHRRVAHSTVRMFSTGNPQTKKTFEQHVLSEFKELLGLFVAKTREVQFFQPMTYLVVSTANVMSAVCFGKRYSYDDEEFRQVVGRNDQFTQTVGAGSIVDVMPWLQYFPNPIKTIFDNFKKLNREFSDFIHDKVVEHRKTMESCTMRDMTDAFIVALDQIRNKTGALKDYVVPTLGDIFGASQDTLSTAKQWIILVLVKYPEIQQRLQKEVDRVVGRERLPSIEDQPQLPYIMAFIYEVMRFTSFVPLTIPHCTVTDTSIMSYPIPKNTVIFINQWSINHDPSMWAHPDTFDPERFLDPEGKLNKDLTSNVLIFSLGKRRCIGEELSKLQLFLFVALIAHQCNITTHPERSPTLEYSYGLTLKPHAYVIAVSLRQDATAAP
The following text describes a protein:
Function:
Involved in the anaerobic metabolism of phenylalanine and phenylacetate. Catalyzes the oxidative decarboxylation of phenylglyoxylate to benzoyl-CoA and CO(2). It can also react slowly with 2-oxo-3-methylbutanoate and use different electron acceptors such as benzyl viologen, methyl viologen, FAD or FMN, but NAD seems to be the physiological electron acceptor. Also catalyzes an isotope exchange between CO(2) and the carboxyl group which proves partial or complete reversibility of the oxidative decarboxylation reaction.
Sequence:
MSTATLEKAVAAKAPRKQKVILAEGNEAAALGVALARPDMVSVYPITPQSSLVEHVAKLIADGRMDADIVDAEGEHSVLSVLQGGALAGARTYTATCGPGLAFMFEPYFRTSGMRLPIVLTIVTRDGITPQSVWGGHQDAMTVREAGWIQVYCESVQEVLDTTVMAFKIAEHHDVMLPVNVCLDGNYLSYGASRVELPDQAVVDEFMGEKNVNWHVALDPLRPMAVDPLTGGTTGKGPQTFVRYRKGQCRGMQNALSVIEEVHADWAKRIGRSFAPLVEEYRLDDAEFAIMTLGSMTGAAKDAVDEAREAGKKIGLIKIKTFSPFPVEALKKALGKVKALGVIDRSVGFRWNCGPMYQETLGVLYRLGRHIPSISYIGGLAGADITIPHVHRVIDETEALLNGAVAPTEPVWLNEKD
The following text describes a protein:
Function:
Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
Subcellular Localization:
Preautophagosomal structure membrane; Multi-pass membrane protein.
Sequence:
MSGEDLTQPNYNLIDNKEDQIESINCPEPSFPWFYKLWRVQGYYNLLILKCYPIIQVFVIAFLGIFLIYLDYSTFIGFPLKPITTNDGTLPAFFDFFVTSRLRNVLVSIVGIFVIISLIYYGYKLYKIMNDENLLNANKFFNDRKVLSVGGDWNKVKRMLRYSQSTETELDPEGFTTSTLIMTSGYFDGDVEMENDSESSESINEIKDVKQEEGEVKIEGLEELPKKSKQKEENLFIKRCTLSNDLMSKLITQRENELRKGSRYLYKIIKDIYFPNKEIDFYKSLIQEEHKFHIPNVNQWKERIKNKVNEYKRWYIQPIVLIKLLYNLIVLCLKYFGILLSPSLLLKKQWTYYSQYLLRQTHELGHETEVRMKSAEDVIEGIISLTPIDQFNRAIMRNLRAVFMLVFVVFFTLNIRSEFQLFGISSAVICNILLTIVVLCYDSSQKEIQSQTYDSARDALTECFPQLKNIVRENSKQKDVINYIKKNMYKELYQCLIDEIIAPLKVYKILKQCGTNSDVNEILQNVIKPVIEE
The following text describes a protein:
Function:
Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in development and differentiation.
Subcellular Localization:
Nucleus.
Sequence:
MTGKKLPPGGIPGIDLSDPKQLAEFARMKPRKIKEDDAPRTIACPHKGCTKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPYVCPFDGCNKKFAQSTNLKSHILTHAKAKNNQ
The following text describes a protein:
Function:
Involved in phosphonate degradation.
Sequence:
MNYNQPATLQAAILDWAGTVVDFGSFAPTQIFVEAFAEFGVQVSLEEARGPMGMGKWDHIRTLCDIPAIAERYRAVFGRLPSDDDVTAIYERFMPLQIEKIAEHSALIPGALQAIAELRGMGLKIGSCSGYPAVVMEKVVALAETNGYVADHVVATDEVPNGRPWPAQALANVIALGIDDVAACVKVDDTWPGILEGRRAGMWTVALTCSGNALGLTYEQYQALPAAELERERTRIEQMFEGSRPHYLIETIAELPAVVRDINARLARGEMPQGN
The following text describes a protein:
Function:
Degradation of glucosinolates (glucose residue linked by a thioglucoside bound to an amino acid derivative) to glucose, sulfate and any of the products: thiocyanates, isothiocyanates, nitriles, epithionitriles or oxazolidine-2-thiones.
Subcellular Localization:
Vacuole.
Sequence:
SFLLIQYEGAYLTDGKALSNWDVFTSISGKIADGSHGKVSVDHYHRYPGDLDLMKDLGVNSYRFSLSWARILPKGRFGDVNMEGIDHYNRMINAILKRGMEPFVTLTHYDMPQELECRYGSWLNPQIREDFEHYAEICSRHFGNRVKTFANCTSGGSDIEPLVTAHNIIRSHLAAVSLYREVFQEKQKGKIGIVMNAIWFEPVSDSLADRLAAERAQAFYLTWFLDPLVFGRYPKEMQKILGKDLPKFTRDDLKSSKNGLDFIGINQYTSRYAKDCLHSVCEPGKGGSRAEGFVHSNAIKDGLALGEPTGVNWFNVYPQGMKEMLMYATERYKNIPLYVTENGFGENSTGVLLNDYRRVQFMSNYLDAFKRAMRKGADVRGYFTWSLLDNFEWISGYTVRFGMYHVDSNTLERTPRLSASWYKNFIFKHTSSQSKDDA
The following text describes a protein:
Function:
Component of the TORC1 and TORC2 complexes required for the regulation of the cellular respons to changes in available nutrients. Required for normal entry into S phase. Regulates activation of the DNA replication checkpoint. Required for efficient phosphorylation of mrc1, which is essential for the activation of cds1 kinase. Also plays an important role in genome stability.
Subcellular Localization:
Cytoplasm.
Sequence:
MKSFASELSKPIQKPRLKEILKELQHIGVPSPCNLRLYHELISVIVPTFWNGKINSEIDFLLAKCFSTLLGLKLLCVRLDNFVQEANLQNIHLVTVYLELLEKAFECIDLDDNCKLIWESTVLSDHQKQSLWTEFIFFLGNFKITNSMSAAMLTFKVYDDSKRLKASSMADYIGVLSSKLACIISKPAVKTPEIYSKLFHYLLHSSNLKAFINPLIPLTQKFCVQLQKLFADLTVSDQMLFLNQLLLEHNTKYPTNFSYSTARDDRITGSLATLLRLNFSSTHFLRLIEFYWGVPTNLIIKRVEVVCSSISYKESDKKELEKTVDSLFNIWSNAQFLRSYTLLAQESLTIYLLLFIPKLEAKYLNNLSKSLMFSNAISCRLDSLDDDIRMHGMIMAEVISTYSGVSLSNPLAFDVPIMKTTKAKVLKSLSSLKDEFLPIEILNDESVIAETSIEKEETNVTHLEKPVISKNDDLIRGDDLEPYDFPDIDSEDTDDDPTVSRSKTHSPVYVQDLCKMLKDTESFEKQRVALENASKLIKRKSAFGTELRDHADELLQTLISLQNRFDLMNFDEMQMTAIVELLLTCLDICGPVICTNLFVSDYSMRQKILILSCISLAASKFNDDDNERLFPSQLLPGNLHDQFYSPTIEKISDELERKLVFPVMSECKDYAEGPKFLQTRYISKQSEIESKKPLPKANRLSLKVDKSLFLLLTSGYMLASRKTAFIEPLFLVYYLKTLGILFFETFTSKIEGANRMLREYVDVLNEVCRLRSDTPEVNEGLLFSFLAILEISSGRTLANEFGKHLLFFEAYTKFLFESPDQGEKVKSLSAAVLILFENKLSEFRTLALEKLLDDSAPLVPERFGLAGL
The following text describes a protein:
Function:
Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway.
Subcellular Localization:
Endosome membrane.
Sequence:
MFERTLVDLIRGIRNHKKNETKFINQCINEIKEELKGDMQKKTVAVQKLTYIQMLGFDISWASFKIVEVMSCNKFSSKRIGYLAASQSFNEGTDVIVLATHQIRKDFLSSNQSEAYLALNCLSNICTTDLARELANDILTLLSTQKTHILKRAITVLYKIFLRYPESLRPAFPKLREKLDDPEPSVVSCSVNVICELARRNPKNYLPLAPVLFRILTNTTNNYWMLIKIVKLFAALTPHEPRLGKKLIDPLTNIINSSPSVSLLYECIQTCITGMSDHIPLMKLCISKLRTLIEHNDQNLKYLGLLALNNIMKIHPKAVSEHRDLVLNCLEDDDISIRLRALDLLPGMTSKKNIGDIVFKLLDHLDNAEGQYKEQIIEKIIELCSMGTYQFITDFEWYINILVKLSQIQDSIHGKLIASQLLDVVIRVKIVRAYSTRQMIELLKNPKLMSNPTEGGMCEVLYAAAWIVGEFSGYVNRPIDALEAFLQPRVCVLPSHIQSVYMLNSLKVFSHACAKANGDKIPSLDDDDEEEEAQEEEDQNEITHEIVQECLEIIKSRLTIFTHSIYLNVQERACLINELLSFYTVTKEQGNNISKELISLFTEQLNPVGPKAQKKVPIPEGLDLDEWINDPKHQEPIEEDEDDDIFNTSTSSHQKKHHKHHRGGYDGDDDEDDETNSSHSGHSSSNFNRHPIDIQRQKEERLRKQANNPYMLGGKVSKKLSTNDPENIPVVQLTGDLGHLHVGASSNRPMPSKGSKKTKKHYTIDTTTEMPEGAKESDDEDEKDNKYKNDALSNINLSEPLTASDVLHTSRHRTDIIKEKEREMAMLAKKNAKLSPKSPPSTANYSEVTSPEIAPAKKATKKAAAGSNPPPPPTAKKSSKKPAATSSTTTTTKSTQAAAAVVAPPPVIVKKVLKTILDDDNFKITCEILKVSPSNETDNNQIKLTMKVQNKTDEDMSDVSISLKNPAEQCVSIKNSGEIGVLEADASTTHTELLNVVNVLNSQELQFTLLASPSSSPSITNQLSIDLPFSFFIVATKLPKDKFAEILQKSGQVSAMDSTKITGQSLTMPLVIEKLAQQLSIEVVQAHPNGQTASFYAKTTQNHHIAMLVKEKDGNISFDIKSPQSLLNQILVKEIAQLTFSSK
The following text describes a protein:
Function:
Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
Subcellular Localization:
Nucleus. Cytoplasm. Mitochondrion.
Sequence:
MRLVSWNINGIRRSPEALRHLLDSLGADVTCLQETRVTRDLLEEPLAIVEGYSSYFSFSRCRSGYSGVATFCKNNATPGAAEEGLTSLLTTHQGAVGSYGNTEEFTEDELRSLDSEGRAVLTQHQIRTSDGQEKTLTIMNVYCPHADPEKPERLTYKLRFYRLLQLRAEALLQAGSHVIILGDVNTSHRPLDHCDPADLECFEENPGRQWLTEFLWQPDRDSGLFVDSFRHFHPTTVGAFTCWSTATGARLTNYGTRLDYILGDRALVLEEFEDSFLMPEVEGSDHCPIGATLRTELIPAPRCPPLCTRYLPEFAGRQQKLSRFLIKLDPNSAEPTSAQFQEKNDGVPLKTRAKKTCGDPGQGQLSLLRFFQAGRPPEKPLITGAQEPKTDPASQDPRAVVPPLPEPSRGQAAFWKAVLKGPPRPPLCKGHGEPCVLRTVRKAGPNFGRQFYVCSRPVGHISNPAARCDFFLWVSGKTPVTH
The following text describes a protein:
Function:
Component of the A-type ATP synthase that produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MSQKVLPTKINLIQFRRQLRLITVIKRLLENKREVLLLYLRTYASQYEKIYNEVNEEMKKVYESYLQAVASEGISNIEEMALSQKPSLEVNSAIKVIFGVKVPTIRLDKSTIPAKPFSDVETSPYLSESYEEMTEALNKIIELVELESTIRSLVSELRKTQRLINSIDNYILPFYRGSIKFIKQILEDRQREEFSRLKIIRRILQRRRESGSR
The following text describes a protein:
Function:
Part of the ABC transporter complex dalSTUV, that imports D-alanine into the cytoplasm. Helps protect the organism from oxidative killing by host neutrophils through sequestration of D-alanine, a substrate that is converted to hydrogen peroxide by the host enzyme DAO (D-amino acid oxidase). DalS shuttles D-alanine from the periplasm to the DalTUV complex situated in the inner membrane and through hydrolysis of ATP, D-alanine is transported across the membrane into the cytoplasm. Not required for the metabolism of D-alanine found in the stem peptide of peptidoglycan.
Subcellular Localization:
Periplasm.
Sequence:
MLSKKFGLSMIVLGIMSSSAFADSIVEGRTLNVAVSPASPPMLFKSADGKLQGIDLELFSSYCQSRHCKLNITEYAWDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPYYINSFYLVSMANHKITLNNLNELNKYSIGYPRGMAYSDLIKNDLEPKGYYSLSKVKLYPTYNETMADLKNGNLDLAFIEEPVYFTFKNKKKMPIESRYVFKNVDQLGIAFKKGSPVRDDFNLWLKEQGPQKISGIVDSWMK
The following text describes a protein:
Function:
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Subcellular Localization:
Cytoplasm.
Sequence:
MLRVTKLHKKQISRLIQSPNIYNITSFQYSTSSTPVSGKPTEKPINEGNTISFNKIDFPKLIQNNNNSNNNNNNNINNNNNNNNNDNNNNHQKFQLQQQQQQQNRPITLNLKFNPPDLNKQPPLQPPLQQQQQQQQPQKSHQSPIFNFPINGNNNNVTPKENPLNMFSFGSLQKPQLQQQQQPQQPQQPLQQQQQQKQNPPQQKKLASFLDYINKTTLNQKPTITTNQNNIKNLSNLGFGDIVSNKPAPTTPTTTTTTTTTTTTPETMTTQQQGQEKTNSNSKIPIPKFQELSKKESDLIAEREKEKEKLREKEREKERKKKEKRMLRQQQQQEEAYGFVNEHQPLFRSKEKEKIGGSGNGEFNKKKTITPVLLPDTVTAENLAPMIGQSIVELIKWQIKAGLKPTSRYEPIVDDILLLMGQDYYFSPMRVLSRDILLQRKEKELKLKANPLWPSRPPVVTVVGHIDHGKTSLLDFLRSTSVVDNEPGRITQHIGAFEVLINDRSDAKKAKRAITFMDTPGHSAFSTMRERGVGITDIVLLVVAADDGVQEQTIEAIKAIKKNDVQVIVVINKMDKPDANPELVKMELLENGIACEGVGGDVPCVEISAKTGMGIQTLEETILFIGDMMELKAPVKDVQVSGVVIETSFKRNRGTYSTILVQKGILKINQFFVCGESHGKIKEMKNHLGTQLKEGKPGQAVEIFGFKEGAPPLGEEFFVFDSEKEVLAIIDERKERKISEDTRREIKKMAYGKEDEEEDLDNEEEMNGTEDLGDIEKKTVRFFVKGDVTGTAEALSAMLFTLPQDPEISIDIQRVGYGEVTENDIKDALFLKTPIVYFGSKLNPKILDSCKKQGVKLIQSDVIYHVVNHVQEYLESILQPVTIFNVTGRAQISQVFDINDGKEKVAGCKVEDGIIKKGAKVHVMRNGDSVHEGRVEVIKSFKDIVKEIGKGHECGITLREYNGIQVGDLLVSYTQDSESRKLGEFVKYRFNTTF
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MPTVDGETASLSTRDVANASVTYIGSVSDSDQCLHLKIYLLSLGANVKEEVSDDLPTDFNDIMEGITTLLDSQVDTDEMRSALYSLCTLLMKCMKSGLTGYISKLCSMFEQNGKQDNAGIRLEILQTLSFYELTSDLEKTEIFVTSLKLAKQYKLHDRVMTDIQEVSKLLDTWKVERDGRIIIYRLIRDIFIDSQRNDEAAVVMLELLRSYDDHNIASSVEDAKICVIDALKNPEIYLFDYLLALKPISNLRGELLYDLLNIFIHEDLKSYVAFYEKSKEFMQSIGLSHEENLRKMRLLTLTSHIAKAGDAATFDDLAAALALEEDSLEQYIIDAISCKLISAKIDEKEKKVIVKWVKSRTFGKAELKQIGERLLKWKNNLHLIRKNLSTISQTV
The following text describes a protein:
Function:
Catalyzes the stereoinversion of LL-2,6-diaminopimelate (L,L-DAP) to meso-diaminopimelate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
Subcellular Localization:
Cytoplasm.
Sequence:
MSQFSFTKMHGLGNSYIYVNMFEEQIPEEDLALVAEKVSNINTGIGADGMILICPSDVAPVKMRMFNNDGSEGKSCGNGLRCVAKYAYEHKLVEETVFTIETLAGIVTAEVTVEDGVVTLAKIDMGAPRLTRAEIPMLGESETPFIRENFLYNNHRYAFTAVSMGNPHAVIFVDDVEKAPLTTLGPVLETHEMFPERVNVEFIEILNEDEMNFRVWERGSGVTQACGTGACAAVVAAILNGKMERGKEITVHLAGGDLMIAWTEEGNVLMKGPAEVICRGVYEYKIEA
The following text describes a protein:
Function:
Cell surface proteoglycan.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MIMAAWQRTLLPFGALFAFLCTCLADLRPSTECKDALTLYITKTSNLNSVTERAVPGDQLRNICPQGQTCCTEEMEEKLALQSHVDFEKLVSEKTAFLRSTFISKTEKFDAFFQELLDNAEASLHQMFVRTYGVLYEQNSEVFTDLFAELKAYYSGANLDLLEVLDDFFAKLLQKMFQLLNAQYTFDEQYLECVSLNMEELKPFGDVPRKLSIQVKRAFIAARTFVQGLQVGRDVVTKVSQVLPTTECGRALMKMMYCPYCQNMPEVMACNNFCLNVMKGCLANQADLDVEWNNYIDAMLMVADRLEGPFNIESVVDPIDVKISDAIMNLQENSITVSSKVFSGCGEPKFGKMKREAGQPVRDGFRGGSSFTQLSSRFRAPNSDDERPTTAAGTSLDRLVRDIRDKIELFREIWSRLPYSICNDEKIAAPAGNDKNCWNGQFKGRYLPEVMGDGLANQINNPDVEVDVSRPDALVRQQVTQLKLITSKLKNAYNGLDVDWIDSSDWTSSGSGSGSGDGDTDIWFSTTPPSTDKINSRASQSDATVVRPALTLLLLPLAALLLCLRSL
The following text describes a protein:
Function:
Probable plus end-directed motor protein that functions in the NACK-PQR (NPK1-NQK1/MEK1-NRK1) MAP kinase signaling pathway, which is essential for somatic cell cytokinesis, especially for the cell-plate formation and its expansion. Regulates the activity and the localization of NPK1 by association through the non-catalytic region of the kinase.
Miscellaneous:
MISCELLANEOUS: Expression of a truncated protein lacking the motor domain causes inhibition of phragmoplast expansion and multinucleate cells.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, phragmoplast. Note=In interphase and prophase, detected in the nucleus. From prometaphase to metaphase, found in the cytoplasm in patches. At anaphase, distributed around the spindle midzone and on the phragmoplast equator at telophase.
Sequence:
MTVRTPGTPASKIDKTPATTPNGHRGREEKIVVTVRLRPLNKRELSAKDHAAWECIDDHTIIYRPVPQERAAQPASSFTFDKVFGPDSITEAVYEEGVKNVALSSLMGINATIFAYGQTSSGKTYTMRGITEKAVNDIYAHIMSTPEREFRIRISGLEIYNENVRDLLNSESGRSLKLLDDPEKGTVVEKLVEETASNDQHLRHLISICEAQRQVGETALNDTSSRSHQIIRLTIESTLRESSDCVRSYVASLNFVDLAGSERASQTNADGARLREGCHINLSLMTLTTVIRKLSVGKRSGHIPYRDSKLTRILQHSLGGNARTAIICTLSPASSHVEQSRNTLYFATRAKEVTNNAQVNMVVSDKQLVKHLQKEVARLEAELRTPDPANEKDWKIQQMEMEIEELKRQRDLAQSQVDELRRKLQEEQGPKPSESVSPVVKKCLSFSGTLSPNLEEKAPVRSERTRNTMGRQSMRQSLAAPFTLMHEIRKLEHLQEQLGDEANRALEVLQKEVACHRLGNQDAAETIAKLQAEIREMRSIRPLPKEVEVGSVVAVNKSVSANLKEEIARLHSQGSTIADLEEQLENVQKSLDKLVMSLPSNNDQQSNNDTTQKAKHPSKKKKLLPLTSSNSINRQNFLKSPCSPLSTARQVLDCEVENRAPDSDDLSCEIQPDETPTKSDGGDVSSKEGTPYRRSSSVNMRKMQKMFQEAAEENVRNIRSYVTELKERVAKLQYQKQLLVCQVLELEANEAAGYNLEDDENIHQIPEESPVSWQITFKEQRQQIIDLWDVCYVSIIHRSQFYLLFKGDPADEIYLEVELRRLTWLQQHLAELGNATPARVGNEPTVSLSSSIRALKREREFLAKRLTTRLTAEERDYLYIKWEVPLEGKQRRMQFINKLWTNPHDAKHVHESAEIVAKLVGFCEGGNMSREMFELNFVLPSDRRPWFAGWNQISDLLHI
The following text describes a protein:
Function:
Functions as a zinc transporter.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSTGPPMSSLDTQFPATHGHGFGHSRGHGHSRSKRWTQPPVGQSLSSLNGSATPVQSVLPSVDAVSPNGSALGSLSHNHHHSHSHSHGGANHPGSCDHGHSGHYHPSERTEDATELRARAVPVISTDFTPSTNRELLSGLLTTLPWIALSWYYNQYANRNSDIDIANTDKVDPNTLAGGSLDQVVLRTCSLTAVSMVMTGVGQLQWSSKAGNKSAVKVPNLRADFAGVALARIFSIALPIYAALEVSGFLVSLGVLLAAASGLPALAKGRAAGSDTREKLAHKRFTVALILTILVLSFFGWVGSYDSRSYFGHLALLLSIFVMPPPFADVGQSSSRGTGFGVSASSKSDALARRISGSLSVVSPDDGILTLVLGLVVGLIGFVLFGIPSLSALDAMYLLVAAGSYATSLLFSSPPHLRSLHKWGLATGIVAAGLLSSPPIAADNRVVYASRCTLAVMSFFASRFDDRRLRLERHSHHNQHHDGHSVAPASRMTKVLLRHSEPYPLLYSILKERDSRRIFYFMTLNFTFMLVQLSYGFITGSLGLLSDSIHMFFDCLALVVGLCAAVMSKWPSSARFPYGYGKVDTLSGFANGIFLMIISIEIIYEAVERLSSGSQMHRLGELLAVSVAGLVVNLVGIMAFDHGHAHHGHDHGHSHSHGNENMHGIFLHILADTLGSVAVVISTILVHFSGWAGYDPIASCLIAILIFASAVPLVTSTAKTLLLALPADIEYNVRETLAGVSSLRGVVGYTVPKFWLDDTETTSGHDHHHRHGHSHSHSHSHSHGHSHSHSHNHSHGHEHNHDHDHHHDHDHDHDHSHEKKTANVLGVIHVIASRGADLEDVRQRTVNYLREKDMDILVQVEREGDGRCWCGGANKSP
The following text describes a protein:
Function:
Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules. Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore.
Sequence:
MSQRPNTPQRDRPTEYRLSLSSNASSRRSSLGNNGRDQHASNQTMIEKYVLPQLQELSDSMVTLDGNMTHMNFIHESIADLNEALSALLYGLMCNSWCVDFPNISHDTPHELKLIQRLEELKQERQALQAKLKPKELTKGSILPLSRQPLSRGSQMLYRDENVPGSTASSNVNIDINDDEDNTAASFVSNPTTFKPQMISSVGASTDFMGKQTVGSASSKLRRRSILHQIRNNAAIGTIPNTLTGITPGERKRSLAVSAKRIPILAGSSTTAGSASSANRESTNTEPALPNRVVRTRQRTYNPKNLASRPPFR
The following text describes a protein:
Function:
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MYQPPRPFELPSDLAAGITSLYRENADAKVIIDSLVKLAYDSGKEQSELVHKKAKVDGPPATLSESIVSKLKIFLGINQVSVVLPIRKKLNVFIGADPRGKTWVWVSSKEDGSVDDMYPATDTADFRCVACLPVPDRSGTPLFNIVFVPGGAAQEVTTPPQPLVFSVPEEPAKKAFDGSLFLQGKDKNQFMYKDLILLGCQGISLPISVPDTEIFGEKFHVLAHKGAREGYLFFMQNEVIFGFKKPLLCMNTEDIESISFSTITRLTFNINIVLKSAPDVAMEFSLIDQSHYGEIAGFMERIAVKNESFDDKLKAKTFMKNQQPDNILAVAQNEAENEVPVAYDDEDEEDDENYTGESSASDGDADESDEEEAEEMEEQEREYDEELGDDEVEHDEDLG
The following text describes a protein:
Function:
Involved in spore wall assembly.
Miscellaneous:
MISCELLANEOUS: Present with 3170 molecules/cell in log phase SD medium.
Sequence:
MKAVFKVTTALLACVFIARYLVCQQNGLGSFATDLQPICRHTEFSVGSLFDSKLVEGSAVSDYLVGKYSQSIKPLIERYPNSSLKRIMGYFYRFWYNIFSFLRLNELCCSLHSKLGPLLNHLRIAWYYLKPYTDNVKNVLENPFNSSTDWMKYGSFSADGTLTKPIFETDSETEDYEDDENENEDEDEDEDEDDVGIEDENKEYEFDGVQDGHGNSQLVTAAILQDLSKIIIGSNSHAELETYEAESLKMEYEAWIKAIDSKIHSAMALLDSEIQSVFEAEVQNKSIEITRNLDDLNTTVNEQLVFLDSKIKDINCTSKFDPVQNKIKYFDESGQVELEAYITKSSITSILKNYKIHLLDFEKSLFHSLDSFLTEMAKLAESIRLENVEVYEEWGDVMISQWSQRMAYMDVRGLHLEDQYDPAYIEENHSNWLRFMELKKKVISERNRLVKHDLDMTLILEWITKLKADFQNTKNNIQDTFLQRMNTADTLFKNRELKEQLEEEFVRQEH
The following text describes a protein:
Function:
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.
Sequence:
MQFSHISDTHLGLVQYGSEERAQDVYDVFNQAIDTSIKDHVDFVIFAGDIFHVPNPNGTAIVQMANGLKRLKQNNIDSFFILGEHDISRIRTTPIPYVYHNLEFSKYIGQGKPIEYKGVLLAGFDKIRKTEIPQYEEKFAEVDKAAQNFSGHKILVLHQGITEFNKFAGELQSTDLPKNFTYYAMGHLHDTDVKKFNHLNGPIAYPGSIELTTSEGIKETKKGFFEVDISGQEANPNWIELDTRPQFSFKTDYQEISKTIDEISEKITSLSKKPIVEVNIQGENIETDHIQAQIARLNSIVLRCFWRISTKQVSDSSVFLDKPNIIDDEMFRLSVDALGSEQAANLAIKELLPVLSSGQIQEASQIIIENFEKFKKERKQ
The following text describes a protein:
Function:
Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate.
Sequence:
MLTILKLGGSILSDKNVPYSIKWDNLERIAMEIKNALDYYKNQNKEIKLILVHGGGAFGHPVAKKYLKIEDGKKIFINMEKGFWEIQRAMRRFNNIIIDTLQSYDIPAVSIQPSSFVVFGDKLIFDTSAIKEMLKRNLVPVIHGDIVIDDKNGYRIISGDDIVPYLANELKADLILYATDVDGVLIDNKPIKRIDKNNIYKILNYLSGSNSIDVTGGMKYKIDMIRKNKCRGFVFNGNKANNIYKALLGEVEGTEIDFSE
The following text describes a protein:
Function:
Modulates secretion by lacrimal acinar cells.
Subcellular Localization:
Secreted.
Sequence:
MKFTTLLFLAAVAGALVYAEDASSDSTGADPAQEAGTSKPNEEISGPAEPASPPETTTTAQETSAAAVQGTAKVTSSRQELNPLKSIVEKSILLTEQALAKAGKGMHGGVPGGKQFIENGSEFAQKLLKKFSLLKPWA
The following text describes a protein:
Function:
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MYSLARPFLFAFDAERAHALALRAIDTAYRTGTTALVATRPVPLPTPAFGLMFPNPVGLGAGLDKNGEHIDALLALGFGFVEIGTVTPKPQEGNPKPRMFRLPEYQAVINRMGFNNLGVDVLVKNVQRARRRGGLLGINIGKNKDTPNEEATSDYRYCMERVYPLADYITVNISSPNTAGLRELQEEQALRRLIADLRETQEALAAQHGKRVPMLVKVAPDLNDRDIDAAARVLADLAVDGVIATNTTVTRTLVASHPMAEQAGGLSGAPLLGQSTLVLRRLRARLPESIPLIGVGGITSGADAVAKMAAGASLVQCYSGLVYRGPRLIGECVDAIRRRRESPSGGAVGPL
The following text describes a protein:
Function:
Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.
Sequence:
MSGLISMTFRPLALADLVLLHEWLARPHVAQWWGPPPSGAEVEEEYGPLLDGTGPHRAYIALQAGMPIGFIQSYTPVACHGEGWWLEEHDAGVRGIDQFLAPADQLGRGLGTAMVLAFVSELLADPGVTRIQTDPSPQNRRAIRCYEKAGFRAVREIDTPDGCALLMYYDRQV
The following text describes a protein:
Function:
Invertase that cleaves sucrose into glucose and fructose.
Sequence:
MALIAAMDVSHNGRVKCMETTGSIFEIDDSDVFKLMERPTPVNVARNKSFDERSLNSEFSITLSPRFNHRNHQEFGSPTERSGFSTPRSGGHFEPNPMVAEAWESLRRSLVYHRGQPVGTIAALDHSVEELNYNQSWEKRIDQFKLGEGVMPASFKVLHKPEKNIETLIADFGESAIRRVAPVDFWWIILLRAYTKSTGDSSLAETPDCQRGMRLILNLYLSEGFDTFPTLLCVDGCCMIDRRMGVYGYPIEIQALFFMALRCALILLKHDDEGKELIDRVVARLRALSYHMRINKFNVMPDSLPDWVFDFVPTRGGYFIGNVSPARMDFRWFCLATPEQAAAIMDLIESRWGELVGEMPLKICYPAIESHEWRVVTGCDPKDTRWSYHNGRSWPVLLWLLTAACIKTGRPQIARRAIELAETRLSRDHWPEYYDGKVGRFVGKQARKYQTWSIAGYLVAKMMLEDPSHLGIISLEEDKQMKALVKRSASWTC
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
METFFFTIVAAVAVLASILVITCKNPINSALSLILTFFCLATFYVMLDAPFMAAIQVIVYAGAIMVLIVFVIMLLNVRTEAGRRSSHTVLLGSLVGIFTLVQLFYVLNRSSLTGNKGEISPELIHRIGHTEIIGKALYTDFLLPFEVTSILLLVAIIGAVILTKKKI