lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Autophagic substrate degraded in the vacuole by non-selective autophagy. Requires ATG8 protein expression to be recognized as an autophagic substrate. Acts probably as a receptor for autophagosomal degradation of ubiquitinated proteins. Targets ubiquitinated protein aggregates derived from denatured or damaged non-native proteins generated under stress conditions. Functions additively with the E3 ubiquitin-protein ligase CHIP for autophagosomal degradation of proteotoxic aggregates formed under stress conditions.
Subcellular Localization:
Cytoplasm. Vacuole. Note=Forms large punctated cytoplasmic structures. Recruited to the central vacuole by non-selective autophagy.
Domain:
The PB1 domain mediates homodimerization; The UBA domain is required for ubiquitin binding; The LIR motif is required for the interaction with ATG8 proteins and for vacuolar import. The LIR motif is required for NBR1 function as receptor for autophagosomal degradation of ubiquitinated proteins under stress conditions.
Sequence:
MESTANALVVKVSYGGVLRRFRVPVKANGQLDLEMAGLKEKIAALFNLSADAELSLTYSDEDGDVVALVDDNDLFDVTNQRLKFLKINVNAGVSTNSAAPESSGSSTPAGMPNPVSKIQKGINDVLMAVPNPMRDTISKVYMDLASKASTSSPVVGEMLDCISKLGQLSIPQESSPCSPVTKPGSSGASLSRDVPSAGGKKDISERTQTGRKPVNLNEPTGAHSKTSGHVPNSSGLGANFNECPFSGSTMNYSCPNPVNLNKHPRRVCHSKKSTNGDYWTSLGVFHKGIRCDGCGVLPITGPRFKSKVKEDYDLCTICYSVMGNEGDYTRMDKPVSVQHLHPFRGPFTQFPNPWLSHPVPRATNGGAPLRCTRPKLDSRFVLDVNVIDGTVVAPSAPFTKIWKMRNSGSLVWPQGTQIVWIGGDRFCNSLSVDLQIPKEGVPIYSELDVKVDFVAPELPGRYISYWRMATSDGAKFGQRVWVLIHVDASLKNSVVNEFHGLNLNASPSLDENFPSEFLGIMNYESAQPGSSSVNPGTVKGTDLEGEVGETQAVEKENLLVGEAHPAIPHGHSPSSSSSSFNMVDFPSMPAVEVLSGGSSSTTKDVPVPLQEDIEKNDVEITMLKELEEMGFKEIDLNKEILRDNEYNLEQSVDALCGVSEWDPILEELQEMGFCDDVTNKRLLKKNNGSIKGVVMDLLTGEKEA
The following text describes a protein:
Function:
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May contribute to the immune evasion of H.pylori by restricting M1 macrophage activation and polyamine metabolism. May play a role in promoting prenatal immune suppression (By similarity). Regulates RPS6KB1 signaling, which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction. Can inhibit endothelial autophagy independently of its enzymatic activity implicating mTORC2 signaling. Involved in vascular smooth muscle cell senescence and apoptosis independently of its enzymatic activity (By similarity).
Subcellular Localization:
Mitochondrion.
Sequence:
MFLRSSASRLLHGQIPCVLTRSVHSVAIVGAPFSRGQKKLGVEYGPAAIREAGLLKRLSRLGCHLKDFGDLSFTNVPQDDPYNNLVVYPRSVGLANQELAEVVSRAVSGGYSCVTMGGDHSLAIGTIIGHARHRPDLCVIWVDAHADINTPLTTVSGNIHGQPLSFLIKELQDKVPQLPGFSWIKPCLSPPNIVYIGLRDVEPPEHFILKNYDIQYFSMREIDRLGIQKVMEQTFDRLIGKRQRPIHLSFDIDAFDPKLAPATGTPVVGGLTYREGVYITEEIHNTGLLSALDLVEVNPHLATSEEEAKATARLAVDVIASSFGQTREGGHIVYDHLPTPSSPHESENEECVRI
The following text describes a protein:
Function:
Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex. May be involved in lateral roots and nodules formation.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MSTMVPNSINISTTKDKENSAIDPPLELDAGALFVLKSRGCSDPDGPTEIKVNRELYVKLKIARSWLHCGYHLTTSIVGPVIFSLPFALALLGWGPGLVCITLAALVTFYSYNLLSLVLEHHAQLGKRQLRFRDMARDILGPRSGKYFMGPLQFAICYGAVIGCTLLGGQSLKTRNSKNSPPKDYYINGCKQNVFFGSINAISIISTTYASGIIPEIHATIAPPVKGKMFKGLCICYTVIVTTFFNVAISGYWAFGNQAKETILTNFMDDGKPLLPTWFFFFMTNIFILMQLVAITVICLQPTNELFEKWFADPKMDQFSIRNVIPRLIFRSLSVIIGTMVAAMLPFFRDIIALFGAFGCIPLDFILPMVFYNVTFKPSKQSQTFWINTLIAAVSSILAAVGAVASVRQIVVDAKTYSLFANM
The following text describes a protein:
Function:
Component of intercellular desmosome junctions (By similarity). Positively regulates apoptosis in the early-stage embryo in response to UV irradiation, this is partially dependent on tp53 activation. Required for the survival of cell populations in the developing notochord and skin, therefore required for normal embryogenesis beyond 30 hpf. Acts as a positive regulator of endothelial cell apoptosis in response to blood flow-derived shear stress.
Subcellular Localization:
Cell junction, desmosome. Cell membrane; Multi-pass membrane protein. Cytoplasm.
Sequence:
MFRCGIDYTRCRWILPMLLLFAIIFDIIAIAAQSGWVEDQDAKTHYASMWKQCRGRNDQWDCKSLMEFSWAQAVAALMIIGLIILIFAFIISLVALCSTVNVSLLPFIGLLLILAVIVQIIALIIYPVKFNEQIYEGYYDYTWAYGFGWGATILTLGCAILFCCLPRYESEITGLEKTKYIYQSG
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSKAVGWGAPRDAGWALPRPVEAGRSHEGAALEKAVGRAWRAPALWSLGSSAFSVTGLADPGRAAAAASREMFFRAAWSLVLRRGGLGSRGIHSPGDTAHSKGKMPPYTNYHAQRSYPMPDEPFCTELNAEQRALKEKEKGSWTELSHAEKVALYRLQFHETFAEMNRRSNEWKTVMGCVFFFCGFTALLIWWQRVYVFPKKPITLTAEWKAQQLQRILDMKGNPVQGLASQWDYEKKQWKK
The following text describes a protein:
Function:
Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MTEVGVAPPGPAPNAKAGPDDVIRAVGVASPGSAPSRGEGVAWIGRRRDGRGVSRSLPPDVAGAGPAPSVGGARRGRARARGRAGMSGSESGAGLELLFRWASPGLARPHDALLCFVHWELVTHRYRCLGAGDQAGPEEEESELLPAGWNADPDLFTLRYRRAADHRDPAAAPRELLLKAVPVDGTLILNAMECNSQQVVSLTLNVADYVDEEHLQDFHRYLGGGGPPPSPSPPVGLRGAPRKRVGWGWDWGEVPGRENPTELRPTSDPPGAGGVERIPGPQSGSGAGPVAAKEAMVSGGSPVIRRPQARGSIVSGLHGTPVGPTPGTDTHPALDTGRWAHTQRSDRFIAEATVLARWRKTFPVPGTGRAVGNAKLKGAKTT
The following text describes a protein:
Function:
Chaperone that suppresses aggregation of proteins with long polyglutamine (polyQ) tracts. Acts by promoting degradation of polyQ aggregates by the proteasome.
Miscellaneous:
MISCELLANEOUS: Expansion of polyglutamine (polyQ) tracts, resulting in protein aggregation, is a cause of neurodegenerative diseases in human. D.discoideum, which encodes many proteins with long polyQ tracts, is resistant to polyQ aggregation, thanks to proteins like hssl63/srcp1.
Sequence:
MTILSTFTSFSNPPKLNKSSFSSSTGSSLSMGSNSFAWGGGWGGFGGPKGGSFNVDIAGNLIWGVYGFIRGGVGLVKWRGLQKGCKQP
The following text describes a protein:
Function:
Plays a role in intracellular Ca(2+) homeostasis. Involved in cell protection against oxidative stress in strain 25W.
Miscellaneous:
MISCELLANEOUS: Strain 25W was isolated in the ocean, whereas the reference strain PAO1 came from wounds in infected humans.
Subcellular Localization:
Periplasm.
Sequence:
MKLRHLPLIAAIGLFSTVTLAAGYTGPGATPTTTTVKAALEAADDTPVVLQGTIVKRIKGDIYEFRDATGSMKVEIDDEDFPPMEINDKTRVKLTGEVDRDLVGREIDVEFVEVIK
The following text describes a protein:
Function:
Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus.
Sequence:
MDLEIEAQKPTLDLAKKCLKKVPKMEDAQQYKVLILDDNELQKIDNIDSYLKIEKLSLCKNQLLRMYGVCRLHCLRELNLSYNGILTIEGLKDLVYLTHLNLECNNIKTIEHLNTNVNLQYLNLSENSITSVSDISYLKNLKELYLNGNRISHLRQCDKHLPQSLETLTLAKNNIADLNEICTLSHLNNLNSITIADNPCVQMAGNVVGFDYRPFVLNWCMSVKHIDGFVVTAIESLKAEWLYSQGRGRQFRIGEQIALARYLSSVCPLSGEALENQNERKLRLILSKAQQHQRQLQEQTTLGSDGANQSANNSPSSLRRKGQATRIQSPRVSRLSGRQNSPDAMSNSYHGNLSNNSMSSGHSESSSGGSQLFELTRSLIDNITSDSTIMSQSLDPNMLASSNNTAASANSMAGTGTGNECIVLSKQHSTATNQNHGNLYNDQTLNPAVITGGGPLTAASKMVPVPESLMSPDCGPTTTTAASIVQRNMQHCNMQPQPQTPQIPKAVKTKDIHRTGGSQAGGGIPVATVNPKSGSPRTAKRNNSSERSSPSLSPRKTLNSHSSNGGGGGSNSHSRPVSSQSKYSVHAAIATPSEGGSSNAVSSDDDSETINVEKLRTIRHKAAQQQTHHTLQHVGQGSGLKMKDKEAALSGVPAAKEAMDDNKATENSAILIQKLWRGYVTRKRTRDVVEKLFHKRTNDHILQLTKDMQITKEQLESGRKIQQLQMKALRQLWRKVSSMNPAEQSFATQNISGPTQVTVSEEEENCEQLAGDGAEHSTLQDLTKSCSMLMNQVQQLQGAVRDIVSCMQFLVHVPQPAQPSMSNASQQLQCSSETQTEIVAVHTPQLEQMPETFPFGKMLDDAAKEQLLVSCNNKLSRPSTLPISSAETSPKLAGQEQSINVRESPRESTDKDSINCEVQMIRIEEADRGNEEENNDGEQKERDEKEMESIAQSKAVESDPVNP
The following text describes a protein:
Function:
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
DGSGGASDAQKQHDVNYLLFKVYEDVNDENSP
The following text describes a protein:
Function:
Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
Sequence:
MSVSPEFTRGKIHDVVVKPLGKFLDERGWLAELFRSDETDPATMPVMAYVSMTRPGIARGPHEHVDQTDWFCFIGPSNFKVYLWDSRPDSPTHGVKQTLFAGIDAPMSVIVPPGVVHAYKNVGGVDGIVFNAPNRLYAGEGKSSPVDEIRHEDVAGSPFILD
The following text describes a protein:
Function:
Zinc metalloprotease that mediates intramembrane proteolysis of proteins such as ATF6, ATF6B, SREBF1/SREBP1 and SREBF2/SREBP2. Catalyzes the second step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2: cleaves SREBPs within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Mature N-terminal SREBP fragments shuttle to the nucleus and activate gene transcription. Also mediates the second step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B). Involved in intramembrane proteolysis during bone formation. In astrocytes and osteoblasts, upon DNA damage and ER stress, mediates the second step of the regulated intramembrane proteolytic activation of the transcription factor CREB3L1, leading to the inhibition of cell-cycle progression.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MLVSTALLLFFIGWSSAFLLDYFLRLKNYRPYLDVADKYGLHVSLFQLRFYTSRSKDVDHYLQSPRAYVDVFYSIGALVAVIAQVGITIYLSVLLFSDIGSFFAKPSAPVLTPPPSTSSLQPAPPPAPIPIFMVVLIVCAVIHELGHAWCARSKGVAVNGFGIFVLGIYPGAFTDIDTNSLNLASPWHRMQIYSAGVWHNLVMALLAYLLFANSTVLLAPGFRAGEGVMITDVDPSSGLYGAGGLQFGDVVRAIDDCEVRSSSSWTSCIRYRQHAIDGKCVSAERVRAGAGSPIHCCPNATVSHLCFETNVLAPRMNQTEPVTKAAPLVELAGGVIVVGRKEEYEQREIYTCLHARETLEGQSCNTTESCSTKGERCVYPALFNGTRLVSLTVAGKGRPVIFVGSFAELKYLVSFTELTPRFPLLFPSFISPAWVPLTVDQLAKYLLAFSLALGLLNALPCFALDGQFIVYTVVHTYLRTRLPKKRRSSLIRLLLCYGTLILVGNITIGFYRLYRTYTTG
The following text describes a protein:
Function:
Involved in the regulation of stress granule and P-body formation.
Miscellaneous:
MISCELLANEOUS: [Isoform 6]: Due to intron retention.
Subcellular Localization:
Membrane; Peripheral membrane protein. Cytoplasm. Nucleus speckle. Cytoplasmic granule. Note=Predominantly cytoplasmic but is also detected in nuclear speckles. Component of cytoplasmic stress granules. Inhibition of methylation alters nuclear localization. Methylation does not seem to be required for localization to stress granules under stress conditions.
Sequence:
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGE
The following text describes a protein:
Function:
Transcriptional activator of the cysJI operon which is involved in sulfur assimilation. Also negatively regulates its own transcription.
Sequence:
MYYDVLKTFIAVVEEKNFTKAAEKLMISQPSVSLHIKNLEKEFQTALLNRSPKHFTTTPTGDILYQRAKQMVFLYEQAKAEIYAHHHYVKGELKIAASFTIGEYILPPLLAQLQKLYPELNLDVMIGNTEEVSERVRMLQADIGLIEGHTNENELEIEPFMEDEMCIAAPNQHPLAGRKEISISDLQNEAWVTREKGSGTREYLDHVLSSNGLRPKSMFTISSNQGVKEAVINGMGLSVLSRSVLRKDLIHREISILHINNFSLKRKLSYIHSPLMENTKNKEIFITMLKSNYQSQLLK
The following text describes a protein:
Function:
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
Subcellular Localization:
Cytoplasm.
Sequence:
MNFTIFEDGHIASPTGFRATGVSAGLKEGSKARDLALVYSQYPCRAAALFTTSVFKAAPVFLSQAILLRNHDAIRAVLINAGQANAGTGQSGLNDAIECAKITADELEVPRDSVLLMSTGLIGVPLPMQRMRNGIRRAVSELDSNGGRRAALAILTTDTRPKERVLRVTLRNGPRFTLAGMAKGTRMIHPRLATVLALITTDLAISQPLLQRALHQSVERSFNRLNIDGDCSPNDSVIMLANGAIDHPPITDSSTWEFGVFQEALDFLCADLAGQIVRDAAGSGKVIKVVVQGAADEAAASAIAHTVARSGSVRAACRRHSSDWGALLAAIGASNVELRPDLLDLRIGTVPVMLRGAPVPFDPTMLVQTMSGPEIELLIDLNLGPAETTVWTCTWTDG
The following text describes a protein:
Function:
Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones; Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
Sequence:
MSKVLFIKASPLPNEVSRSSQVAETFMAEYKAKNPSDTVEELVLYNTEVPLLDLELMTAGRELQAGKAFTDLAPDVQKKLNAYNALTEQFLAADKYVFVFPLWNLGIPPLLKAYIDTFVIAGKSFRYTEHGPEALLKDKKAILIHGSGGIYSAGPTSSFTHGEPYLRTILQFIGINVVPSIFVEGIDHNPSKEAEIVAAAKAVAQESAAEF
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
Sequence:
MSSQRSSSSVFDNDQSPTLLTSSQQPLAMPRFLSQTQNPGQTLEDVFSRLSVSASPFNYPPSDFSAGSSYGVKTPSKILPCNGWGHGVTTLQSSNLWHPAFTSNNYSYYDDGFVDSKPLVRQREKTPTFGGGAFPVFPLSNGMQQKTPDDAGFLYGFLGGNNGSNNLGFSGNERRLRWFNDLRGRVLLLATDQHECRTLQETMRKLTREEFYIIFLELINHVTDLMVDPFGNYVVQRMVEICTEEQLSQIVLSLAQCNFQLVRICLSAHGIRGVEKLLERVTTQEQRDLVLSALCPGAAILAKDVNGHRVLLHCLKQFSGEDNENLLNVVANKCFEIATDKTGCVVLQQCINHAQGETKQKLLDAIILHVSLLAEDCYGNYVVQHLLSLKVPGVAESLLIQLKGRFFYLACNKYGSNVVERFLQDSGEKHSTSIVLELLHNPNVAMLLVDPYGNYVIKSALSASKGHVRNRLERLIKLNSLIMRSNLYGKKLLAWFEKGKI
The following text describes a protein:
Function:
Axonemal protein which is implicated in axonemal and/or peri-axonemal structure assembly and regulates flagellum assembly and beating and therefore sperm motility.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSTNILPMIDPNLGKSNIKPSPPTTPPHKNTINRSTRNIRPINGHNKQKKQKHPVVQETYDKKIDVARYRNDYMHNLCMDILKEGYHRAFAEIFELINRQKEEREALGDDIIATLTPLLKDEHEKLSYLSEKLCRAEDAERNDDQGLLYRELKNLAVYFENHNDSWLSDHFYFRCLEIAQTIEHDDGKTQSEANCNLGVSLVDRGENNEALPYLEEFYNLTKNRDWINDDGQQLFPLACEHLCRVYTAIAAKTSRENSEVSIKFLLQAYDVAKEGGSKHAEGITSYRLGRAFSENGDPQMALTYHNSYLEICQQEGDDIGAARAYEAMASCYESQDDIENTFKNLEKFATVAEKCNQQKEFGKACTKLGGIFNSMGNYSKAVEYFGKAFKVAQEMTDTEVLDEARVQYGIARAHKMTKDYMKFININNRESLRELLSWKSTRQAAFSNDEADSDPNNPSNT
The following text describes a protein:
Function:
May increase the toxicity of alpha-latrotoxin and/or other venom components. Is non-toxic to mice and to the cockroach Periplaneta americana.
Subcellular Localization:
Secreted.
Sequence:
MSPSCPVHRRWLAALLLVSGTLVSHQGAQARNLHKRSFLELGCRGNFEQSYLARLERVCEECFGLYREPQVYNICRANCFKNENFDLCADALLLKDEMSDLRRMINYVYG
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MATIDGPAQHRGPLTICASVCSVTKPRLTSLTPSLDPAGGDGARRGQRRDPGAPPEAVPAEVGALEGPRGRADMKMAGPRPSHTEVLRRRVPRLASPEPTEATLMDTCTAFLAQASSGGHASSCAAEQGAESTGLAPKPVMLGEGESHGESVPGLLQGPPRALGLRDLCGIEEAGEKPGDPPRGLAVYEKAAGQNGHGSTVSGSEVTLNAGSAMDGRGSWKGRPYRCSTCDRGFKCYSDVVKHQSIHSGEKPYECSDCGKAFIHSSHVVRHQRIHNGEKPYVCKECGKAFSQSFNLIRHQRIHTGERPYECPECGKSFSQRSDAVKHRRIHTGERLYECSECGKTFIHSSNVVRHQRIHHGENPYECKECGKAFSQSSNLIQHQRVHTGEKPYACQECGRAFSRSSFLSEHRRIHTGEKPYECSECGRAFRALSGFFRHQRIHTGEKPFRCMECGRAFRLSFHLIQHQRVHGPE
The following text describes a protein:
Function:
Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm, cytosol. Endoplasmic reticulum. Mitochondrion inner membrane; Peripheral membrane protein. Nucleus membrane; Peripheral membrane protein. Secreted, extracellular space, extracellular matrix.
Sequence:
MRVFLLFLPLLGLLEAGPLPDEPVLQTQENFNVNRFMGKWYDIAVASTCPWMKRHKGDAAIGSLELQSSGSPQSLSMTRIGLRRGTCKSISGEYQLTKTPGRFHYHSAKWNSDVDAYVVHTNYNEYALVVMLKQKPGGEKSTSVKLYGRTMELRPTLIEDFKTLVAEQGMSEDTIIIKKNKGECVPGEETTPEPQIQRARRNVVVPPAEEGSGDDMPMFRGPDACKSEPDSGPCFGMLTRFHYNSSIMSCQMFTFGGCMGNQNNFPTEKDCLQSCRTEAACRLPMDAGPCKAFVDLWAFDSSSGKCLSLKYGGCKGNGNRFYSKKECDEYCGAMMRNGDDEFLSVN
The following text describes a protein:
Function:
Required for pollen aperture formation, male fertility and LECRKS7/DAF1 function. Seems to be involved in operculum protrusion. Participates in the modification of plasma membrane at future aperture sites, possibly by creating close contact between the plasma membrane and callose wall to prevent primexine formation and sporopollenin deposition.
Subcellular Localization:
Cytoplasm. Note=Localizes uniformly in the cytoplasm of microspore mother cells (MMCs) during meiosis, in dyads and in the early tetrad stage. In the late tetrad stage, starts to move to distal poles of the tetrad, concentrating into prominent spots. Finally, localizes specifically at the site that marks the future aperture.
Sequence:
MPRPPPPPPPGRGAPGARRPMREFFAAWLSTLRSPLLPLLRRALSSSSSSSSGGWDDPLSSAAAAVEAHFQAHWSALDAAARQDPAQAVSAGDWRSPLELPFLWVGDLHPSLVTSLLRSLSPSPRLLAATDRVDRRIRAAVPSISDRLRRVQEAFISAEVSGAADVEAFLEELKDVALDANRLRRGVLSELVAAAGGYQAALFLEALSRFVLSMHDPEVLRRFDQCRASPGS
The following text describes a protein:
Function:
Probable proton-dependent permease that transports dipeptides.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYNDTHAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSFLYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGYAQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLVLLVATPALITILFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFFSMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKESVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAELFIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINYSINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES
The following text describes a protein:
Function:
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Sequence:
MLSRRLSQREPLTHALSAPYLGGSPPAHAQSAPPRILSLDRAHAQSAPLRGGSPPRMLSRRLPSSSVSIARMLSRRPSAEGVPRACSVGASPKGSPSRMLSRRLSRRESPRACSVGASPHPQSRSRACSVGAPPRRESPAHAQSAPLRLVGPDRAHAQAGPALPTRAEGGGGVRGDARACVRAPEVSWRRPWEARPRPTATENAAEADLWLLNSCTVKSPAEDHFRNSIKKAQEEDKKVVLAGCVPQAQPRQDYMKGLSIIGVQQIDRVVEVVEETVKGHSVRLLGQKKDNGKRMGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVERAKQSFQEGVCEIWLTSEDTGAYGRDIGTDLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEAMAKILSHPRVYAFLHIPVQSASDSVLMGMKREYCVADFKRVVDFLKEKVPGITIATDIICGFPGETDEDFQDTVKLVEDYRFPSLFINQFYPRPGTPAAKMQQVPAQVKKQRTKELSQLFHSYNPYDHKIGERQQVLVTEESFDSKFYVAHNRFYEQVLVPKNPQFMGKMVEVDIYESGKHFLKGQPVSEAQVYTPSISTPLAKGEVSGLTEEFKQVLENGSGPKAHPGAAIQPQRPPGARQDGRQAILTVILILLAVLVALVLKTHQ
The following text describes a protein:
Function:
Required for ciliogenesis. Also plays a role in mitochondrial metabolism where it may modulate complex IV activity (By similarity).
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Mitochondrion intermembrane space. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane.
Sequence:
MSSKFNFSLRRKEKREFRNIAHGLIPAATIAPRPAVPRTPPPRSPNPSPERPRSALAAAILSSSLTGRTVAIPSPRQRSYSESDCSRADSQADFEPYATALYTRDRWPGSVTGRPPVPSPGRTDEDDDEDDEGNDIDELEGLEGDEDHVYQSLERQSRADDINVVYAVPLKHKKSEIDSDVDEETEDSAFDIVSPLQTEEETVVPEGAGQTQPSSLPQPRSVSRRSMASPELDDWSSPRSLKTSKRKSSRTNKESPVRVNERDRSSEDSEVLRSTLEVQHALVKELKEQNQILSQEKETLEKRCLQQSQHMKHLQQELCHTHRERGNSTGEGSELSSLRQQAQELVDENDGLKMTVHRLNVELSRYQARFRPLTKDENAQLKGLPVKGPAPPWLLDMKYLSPLLLAYEDHLNAKDKLLKSCEEELQSLRVRAEEVIQENEKLHTQVSKSSTVSNKEWRQLQEQARLVLEENQVLIEQLELQHAKAKEAHSKHAQEVCKVSKKVMLLEAEKQSLEKELEVERKEHRALKTEFQRVRLALEHSLSLAEHQTVTDKLKRQLQDHEKVKTCEVEDLQVRLSALEVERKTLLLDKTNLNTHIKHLETELQLSQQANRKAQRRVSVLKQQVEDSLEKELIAHQYLANIVTLAEKTTHERDQLMLMASTLEKDKQGVLTRIIESTVNLGKLQEKVKVFLLQS
The following text describes a protein:
Function:
Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Sequence:
MEGSQHNGSSPRIFDIPAKIMDDFCRCMDCLSDWEWMRFASSVIDDQTVLRRIRSYEKTGVSVTRELMWSWGQKLPTLQKLVERLQKLEMYRALGILQQWSPLSVIASKVPERRKAEKESDLKTDNKLPELTYTSPLELPTPPLPAPPPPPSDLLHSLSIQSECSLTCHSPEEVLSIPQQEKSSFSKGLCKIWTQKDVEDATDCFCSSKIIHEGEFADVYMGHKQDKLYAIKRLKKVQDEEQKRMSSFFHTEAQISFRCCHANILPLLGFCVEGDCSCLINQFIRNGSLDLALQQSGNHILNWERRLKIALGFLKAIRHLHSNDILHGNIKSSNIFLDENSFPKLGHSGLRFCPDKQAGYTKAKSKDLQVHQPYLPDSFFRHGQLTVQTDIFSCGVVLAEILTGQKACDKSRNPVYLKDLFLEELERAKEYLDSDGKQADHESPESLCSHQISRKYIDSRAGFLSNNAAFQLSLAACLCLTKKRPLLQEIYTWVEKADQCSRDSQNLSLNVPEESDFDDSLSLEPMEGAISKMPCTSTQGSWSMDDHNQRNHYPKTENRDVDRTPCESDDSTLYVLPTQRSRHLVGAASAICDHQPTQSDALEQTEAVHGNVQFSWQKSREYSDQSADSSSPSWGIIVNKEKEKLLQNFDLYRDNKLDSGSLFDSI
The following text describes a protein:
Function:
May be involved in clathrin-mediated endocytosis.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MRSEAQVPPAQKVYYEELFQIADVDKDGVIGLNDASFFRNSMLSNDILRDIWQLSDVNNGYLNIDDFFVALKLVSLAQMGAPVTLDSIKLIPVIPPPKLNDIPPLKNDWIISNGEKQNYIDLFNKYDEDGDGFILGSQAKTIFGTSGLPTKMLSHIWNLSDVSKDQKLDCQEFIMATFLIRSVLKGYELPNKLPESLITSSHYISSAGVPSPKIPEWLIPPPERIIYEDLFNKNQQGGIFTGSQAKVLFEKSGLSNQDLKLIWDLADHNQEQVLDKHKFVIAMFLISQRKKGKELPQSLPQLLLESSKSTFNPSSITSPPPQSSPQSSQLQQQPPQQQQQTGDSKYNINLNDLVSNTTPIGQPNIQPTTTTTTTPATASGGLNVSGLLSPPPQQQSPSIVGTPPSTITREGSFTFDNSGGGNNLLAKPPRSNSITRMNSFQHQLPQQQQQQVSPQSTISNTSIGSGSSSFLSTNATTSSPPPIPSTSSQPTSSNNSSITSNNNNPISPTSTNITQLFENIEKVKQQVFEQERIRQEEIQVKLNQELQLEAELKQQLAQEQQQLDEVRENVKEEEIKLSSIKADNQSLKEQISTARVDIKSLKSQLEQQSSLLREKSELFDEQNEALSHLNDDLKEKQQELQKNKQQIEQLLSSIESIKQNRTDVKNQISTVTKQLNDSKLELKQLAEEQKQQKQKLAEEQKQLQQLQQQQQQQATSKSLTSVKSDDNITFLSGINTNTTSTNTATSIPTASVSGNDNWDFFNSPPVKSSSSLPTSPFDDDKTFVPTFTTTTTTTNNNNNNNTINTSNGNLTFTSPVKSTVNQLKSSNSSVGGTGGSVSTRKLSGASVSSNNSFNDNTSIDTLNNHFGSDQFSFNSFGSNNLTAPPTTSSSTNKVQSDFFGVGGGNKDPFGGDSNNNPFGEESTSSIRDGGSETLSEAHTLFDKDPLFETNDAFQSSKDPFGQILFSNFTKDSFGGESVSNNSNNSSIISSNTIPSSNFTFNTNSTTTNNRQSPIDSDLFSDNQQQQQQQQQQQQQQQQQQQQQQQPTQSNQNNQSFTSNDSFDDFQTTPTPTNNNNNTTTTEFGVKFSDTTFGDSSNGDFDFGSNVFGQPSANDPFSSSIEPQHQPDTNNVSSDPFKGGFDDFGSAPFSFDNKFNEVVGDDSPSLTTATTTTTNDNDNGTFVFNDNNNNTPSPFDS
The following text describes a protein:
Function:
Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.
Subcellular Localization:
Golgi apparatus.
Sequence:
MGTSLWLQPPRNSPIWQQLATTIQGLKPIFSDSENFEPHITLTSNISVNTQGQVDFVLDRAVAAAKCVPQGFQIHLSSVKYGSRFFKKVYLQVEPTPELLSLARICREDFVYMPEAMSQARNYQAMSAEERQKIDTQVGQRAAEWTRNEYDPHVSLVYSDLYPVEDADRRTIETRLEDTFGSGYDESGLGWKNGRFALVRCEGPVDEWEVLGVRDF