lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Single-stranded DNA-binding protein that plays a role in viral DNA replication. Forms a stable complex with the alkaline nuclease and mediates the transport of the helicase to the host nucleus.
Subcellular Localization:
Host nucleus.
Sequence:
MATKRSLSGESSGEPLIKRMAMASSPKKIRENYKRISGKLMSKMTLSIDNEYHYTFRIMSDNKIQEYYGDSQSFKDMEEGKCYDISLNYVKTKFSQMIQINEYKECEMEIETATPMSDYLTNKHFENEDGVNIIVKYKFIYKKINSGLYKVVFEVVYKNLNDDPDVVQVECSVNAKTLINLFKNNIKGSDDINEVFKYLKDNENQIFTIYSIKCQQIFNGSNVYMNWNVVNSTRIELCEAKESEAYSNLQNCTNAKINISRSNKHVASYNVNVLKSELEENDMGDNKFIVQFKSDELNIADSDDCSTSSDLGKWNKSVFYVNTNKKTEADSLQKLCADFNQISMLLEDNLIKVTIYVTVENGENHNMNVLGLLKYDEDENEYKFL
The following text describes a protein:
Function:
Involved in the biodegradation of xenobiotic compounds, such as nitrobenzene and 4-chloronitrobenzene (4-CNB). CnbZ preferentially catalyzes the deamination of 2-amino-5-chloromuconate (2A5CM) to yield 2-hydroxy-5-chloromuconate (2H5CM). Also able to catalyze the deamination of 2-aminomuconate to yield 2-hydroxymuconate, which spontaneously converts into its keto form, 2-oxalocrotonate.
Sequence:
MPDAVVFSPGGYRYIPAVFQYSAGIAAEPGFEIERVRFHRPVPLAEAFVAVESHLRAIGRPTTSFAQCELRSPDPFNDQGFIDFNTEYVKTLERWGIYKDRVNPVARTNVCPMYDKPTTPSMFAFSYTVPTTSAAKRPSFQLAGGGDARGGSAPYKDRIVAFGDTSPEGLREKVVFVIEEMESRLKTLGLGWADAVSTQLYTVQNIGHLVGPELARRGCGAGGLVWNYTRPPVIGLEYEMDVRGAVRETVL
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MTGTGHGHGHGGLDDSPGFPTSSPYHSKDTLSPTAAPWAHPVPRAPGAGSGSGSPSASGSGSGSSSSGLSPAGSLGLGGAALRLPGDNLITLPRLGADLSGGDAAAGATFSLSLMGGASGSMPAPGAGAAAMAAAAASAAAAAGPRKAPEAVIDAGAPRMPARVGAAGGGGAAGGYGFVPARKRIMTAEDLKRFLEGQTVKDLMAFILSINEAVQGKKAGLGPTGDPSYVPSPAVSRMCGLLDALGALVDAVPPEQQSLRYGNPAFRTWHAKLTERGPLLLAAVFPPDEEEGGAEGQQQQQQQEKAASVAPSGTQQGADTAAASGEAAAAAAPASAFAAEAEPEAGQAAGASTSEQAEAAAAPSSSSSQQQQQQQQQQQRRLPLRAAAVVELLPYLLDSFGNATRIDYGTGHETQFVALLYCLAKLGVFGEADRQGLGLVVFKQYLELMRKIQTTYWLEPAGSHGVWGLDDYQFLPFIWGAAQLIGHPMIKPKSIHNPDILEAYAGPYLYLGCIKFVKQVKKGPLAETSPMLNDVSCVPTWAKVNSGMIKMYQVEVLSKFPIMQHFFFGSLLPFE
The following text describes a protein:
Function:
Mediates magnesium influx to the cytosol.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MGGNSEKKRLLGSDTNITVNDDDGAVSKAQPYVKPEKDGVFTGILRFLGLREKKKPKKDANKEKEFADKFRDLSVLDKQSMLDRIGTPMQGLSEEEVDRRTKLYGRNVITQVKASPWYATLFFAFTHPFNIVLTAIAVVSICTDDYATFSVVMFMVIFSALLCFHEERKSSKAFAHLKSLVRTTVTVLRTRNGISQEMKIDMDDIVPGDIVPLKAGDVFPGDVRILESNSLFVSQSSLTGEFLPVEKGPNASEEPTSIFDTPNICLMSTNIVSGSGIGIVFDTGSRTYISSISEILTSTQTTNAFDIGVRKVAYLLMGFGVVLVPIVIIINGISTRDWKDSALFGLSVAVGLTPEMLPMILNTNLAKGASDMSKKKTIVKQLHSIQNMGAMDVLCSDKTGTLTEDNVKLQHYIDQDQNESDNVLSFSFLNSNFQRGLKNVLDVSIISYYGLKRGLITEEEAEKLLLHGHGNGPTDEDNHTPSGQKKPDPFADSYSLNDEFPFDFTRRRVSVILNCANEPSTKLLVCKGAVEEVLYCCSYVATPNGEAEPLTEQLKKKLLGVMNDLNVDGLRVLSVATKKIENLPSDYKFDVKVDEFGLTFHGFLAFIDPPKSDCAGAIRQLRENNVAVKVLTGDNLAVARKICRDVGIDVSRVISGPELEGVDDEDFDQIIEECSLFAKLTPIQKYNVVKALKRLGHTVGFLGDGINDALALREADVGISVDTATNIAKDASDIILLEKSLNVINTAVITGRITHANTIKYIKMAASSNFGNVFSMLIASAWLPFIPLQPIQMLTQNLLYDFSQVAIPWDNVDEEYLKVPHPWSVKSLFKFMVFLGPLSSIFDVVIFSYMWWKLGWDSETTAQLFQTGWYVEGLITQVFIVHMIRTTKIPFIQRWGSLQLILNTLWVAGVCVAIPYIPYVNTFLKMKTLPAMYYPGLAACFFGYFFLTQIVKKLYMKFFGEWL
The following text describes a protein:
Function:
Alpha-galacturonidase able to catalyze the hydrolysis of the chromogenic substrate p-nitrophenyl-alpha-D-galacturonic acid (pNPalphaGalUA), and of the probable natural substrate alpha-1,4-di-galacturonate (GalUA(2)). Can neither hydrolyze pNPbetaGalUA, nor the stereoisomeric pNPalphaGlcUA. Does not display alpha- or beta-glucosidase activity as it fails to hydrolyze melibiose, raffinose, lactose and the chromogenic analogs, pNPalphaGal and pNPbetaGal. Cannot use the following compounds as substrates: pNP-N-acetyl-alpha- and beta-D-galactosaminide, pNP-N-acetyl-alpha- and beta-D-glucosaminide, pNP-alpha-L- and beta-L-arabinopyranoside, pNP-alpha- and beta-D-glucuronide, pNP-alpha- and beta-D-glucopyranoside, pNP-alpha- and beta-D-glucopyranoside 6-phosphate, pNP-alpha-D-galactopyranoside 6-phosphate and oNP-beta-D-galactopyranoside 6-phosphate.
Sequence:
MFHISTLDQIKIAYIGGGSQGWARSLMSDLSIDERMSGTVALYDLDFEAAQKNEVIGNHSGNGRWRYEAVSTLKKALSAADIVIISILPGSLDDMEVDVHLPERCGIYQSVGDTVGPGGIIRGLRAVPIFAEIARAIRDYAPESWVINYTNPMSVCTRVLYKVFPGIKAIGCCHEVFGTQKLLAEMVTERLGIEVPRREDIRVNVLGINHFTWITKASYRHIDLLPIFREFSAHYGESGYELEGECWRDSVFCSAHRVAFDLFETYGAIPAAGDRHLAEFLPGPYLKQPEVWKFHLTPISFRKQDRAEKRQETERLIVQQRGVAEKASGEEGVNIIAALLGLGELVTNVNMPNQGQVLNLPIQAIVETNAFITRNRVQPILSGALPKGVEMLAARHISNQEAVADAGLTKDTGLAFQAFLNDPLVQIDRSDAEQLFNDMLQCIMQS
The following text describes a protein:
Function:
Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MKCKRPNVTYFEIFPDAVFSVSADFNPRSLKSVDPKCIQETIRGLLDIAVAPKCMTIHHGTLCDRVILAMFDGLDVKRYNKFKEKLPNFVNISQNKFPVFPQAKEREGYLIPGRQTVLGFKNNKKIFKKYNNYEEMITPVTDLLDNGYPLHLEGMKIPEKPRCELYKLSILTEEQLADFSELPEETTPETREIIAIDCEMVETKLGSELARLSVTDFEGKPLLDQLFKPTNEILDYRTPFSGISEETLANVTVTPDQALKILSKYASRKTIIVGHSLENDFRSLKLIHHRCIDTALLYNSETNGVKKPSLFLLYKKYINKPFRANESGHDSYEDARAAMDLVNFSLKDQNIVIEQPKVPDFIAEMIKKHGSLFYAGMTKNIDFPDTDILELKKTESDDETLKEIVDNIANNDLMFAHFAEAGEEEALDDAVLEKCLEKYNKILESLIEALPKRTALIVYVANGNVNRIKQEDDSIPPMNDEKVKDEFLSIRQGLLWVHCSPTK
The following text describes a protein:
Function:
Catalyzes the excretion of spermidine.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAGMVMIKFA
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Miscellaneous:
MISCELLANEOUS: Present with 1550 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Sequence:
MITKYFSKVIVRFNPFGKEAKVARLVLAAIPPTQRNMGTQIQSEIISDYNKVKPLVKVTYKDKKEMEVDPSNMNFQELANHFDRHSKQLDLKHMLEMH
The following text describes a protein:
Function:
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
Sequence:
MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSAQNILVSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQETDDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLILENEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWLSESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLILDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQFAKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADISHYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNEKFQRYAQNPQEGRLIILKENFRSSSEVLSATNDVFERLMDQEVGEINYDNKHQLVFANTKLTPNPDNKAAFLLYDKDDTGEEEESQTETKLTGEMRLVIKEILKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLDTLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMASSQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPARQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIHKSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIKLSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAKNGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQDSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGVEIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLKQVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVRGILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLILLGKDEVQVVKV
The following text describes a protein:
Function:
Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2. Acts as a negative regulator of mTORC1 by promoting ubiquitination and degradation of RPTOR.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm. Endoplasmic reticulum. Nucleus.
Sequence:
MAARELPSFEIVLRSLNSDVPTYVTFVNQCGYDARAWWLNFTGNPVSYGDIKPRTRMRMKTYRSHPWVFRASENGAKLLANMKEIYFPELNDIQDGYPVYLEVKITSPVYSLQDYCIMLVQKLVKKKDFDKLDIPQSLKKDLKEFPNLQKELRDLNRVLHAIN
The following text describes a protein:
Function:
Involved cell autonomously in PLM neuron pre-synaptic differentiation by negatively regulating prk-2 expression and in neurite branch positioning.
Subcellular Localization:
Cytoplasm. Nucleus. Note=In PLM neurons, translocates into the nucleus during the 3-fold embryonic stage and remains nuclear in the adult. Nuclear localization is idb-1-dependent.
Sequence:
MPPQVIQQQQQSLASEMTARDRLTSYIYEYLQQTGASKTAETFKEEVLSTNPAAGLAAANSTKLSDKSFLLEWWLLFWDLYSAAPERRDAGGDPFSAEAKYFHEAMIGMPPGMNGHFAPPPMGMEMMGGHPGAFGGRFAPGRMPPGAMAPGGMPPGAFPMFPPDPRLQRMAPNQGMRMPPPPVGQPFPGAVGMPRPVGPGAPMDMSGMQRFDFMGGPPPGGGAQPFPGASGSGGMMPNGAHPHMSLNSPSMGVPPADMPPFMGMPPMPPTSSSAMPFGMSSDHQPMSAGPAAAAPGATTAGGPGTPGMIGSVPGPGSVPQVATTSVGSVGTPSSIGQQLHQPKQEITTNGEEIMKTEALTPTGGGGGGSVPPPPPAATAAVSMNGGGPGSAPGSAHSVNNNVNPGTPGSNPLSNPMSNPPLSSGPPPPGSNDAFGKDDNGEISKIREGLLDGFCA
The following text describes a protein:
Function:
Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking notably of the Schwann cell and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy (By similarity).
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cell membrane. Note=Mainly cytoplasmic but differentially localized to other regions. Associates with the plasma membrane in intestinal epithelia and lactating mammary gland. Translocated to the nucleus in a p53/TP53-dependent manner. In prostate epithelium and placental chorion, located in both the cytoplasm and in the nucleus. No nuclear localization in colon epithelium cells. In intestinal mucosa, prostate and renal cortex, located predominantly adjacent to adherens junctions. Cytoplasmic with granular staining in proximal tubular cells of the kidney and salivary gland ducts. Recruits to the membrane of recycling/sorting and late endosomes via binding to phosphatidylinositol 4-phosphate. Associates with microtubules. Colocalizes with TUBG1 in the centrosome. Cytoplasmic location increased with hypoxia. Phosphorylated form found associated with centromeres during S-phase of mitosis and with the plasma membrane (By similarity).
Sequence:
MSRELHDVDLAEVKPLVEKGESITGLLQEFDVQEQDIETLHGSLHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNSEDMQEITQHFAVCHVDAPGQQDGAPSFPVGYMYPSMDQLAEMLPGVLHKFGLKSVIGMGTGAGAYILTRFALNNPEMVEGLVLMNVNPCAEGWMDWAASKISGWTQALPDMVVSHLFGKEEIHSNVEVVHTYRQHILNDMNPSNLHLFISAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDNSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLEGTRSRSHTSEGPRSRSHTSEGSRSRSHTSEDARLNITPSSGATGNNAGPKSMEVSC
The following text describes a protein:
Function:
Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MNETSNRDHQVTSKEILDVAFEKSKSKFTTPRQTIQDTEELQSYQQTKRKEFEQHINKNRLNLGQWTRYAKWEIENNHDFPRARSILERALDVNIQHVPFWIQYIQLELSHKNINHARNLMERAINTLPRVNKLWFLYVQTEEMLKNYPMVRAVFERWLDWHPDTSAWDAYINFEARYEEKENVRTIFKKYVHEFPNAGTWYKWIKYEMENNRDDVNTVRAVFESAVDTLLSNKSEENDDDEEFATIISSWTSWEVSCGEASRANEIFKLLLDNKTNKLEISDQTKSSIYTAFVEFEKNFGNKDSIEQSVLIKRRIKYEQEIQNDPYDYDSWWKYMTLLQNSSNKSDLENAFKKVTGNVVHDKHKSIKWRRYIMFWIWYAFWEEMTNNNPVSAREIWNNCLKVIPHKSFTFAKVWIGYSEFELRNSEDGLAKARKILGRAIGQTSINKPKIKIFKYYIDLEKKLGDWNRVRLLFQKWLEVSLLTTSSSELVIEKYVEFESSIEEYDRCDSILSSARQLSENPEYSSSFNLQRLLEITVEFYKEEMQYDKIREIYRALLDKDPNAHNWISFALFESSIPSAEQLEEYLQGDNEEFEATVDESQIESTRNIFEEAMTYFKDKDDKESRLVIIEAWRDFEEVNGSDESLSKVTKRLPVIVRKRRTVGSIEEEYIDYIFPDDESKKLPGKMSKFLANAKKWAQQN
The following text describes a protein:
Function:
Essential cell division protein.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Sequence:
MRDLHVKTRIKPAQTRNRVKRERKPINWRPLITWGSRLVCGLAGLATVGGICYGGYRYLSQWEFAPLPLKEIEVSKLQRLKRDDVIAQAGVRPGDSMLGLRLRDIGSQLAKNPWIDKVQVRRYFPHTLAIEVVERVPVAVVNMGFLYYMDAGGTVFKPLTQGDSLDYPVITGVAEEDLARDPVGTREALKGAVALMDQLRRGKEFTLADVSEIHLDKGFGLTLFTAAGGVPVRLGNGGYEAKLARFVRIYGELREHMAAVEYIDCDYLDKIIVKKG
The following text describes a protein:
Function:
Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of fimbriae.
Miscellaneous:
MISCELLANEOUS: The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.
Subcellular Localization:
Periplasm.
Sequence:
MTNTWNRLALLIFAVLSLLVAGELQAGVVVGGTRFIFPADRESISILLTNTSQESWLINSKINRPTRWAGGEASTVPAPLLAAPPLILLKPGTTGTLRLLRTESDILPVDRETLFELSIASVPSGKVENQSVKVAMRSVFKLFWRPEGLPGDPLEAYQQLRWTRNSQGVQLTNPTPYYINLIQVSVNGKALSNVGVVPPKSQRQTSWCQAIAPCHVAWRAINDYGGLSAKKEQNLP
The following text describes a protein:
Function:
Regulates the mitochondrial network by promoting mitochondrial fission.
Subcellular Localization:
Cytoplasm. Mitochondrion outer membrane; Multi-pass membrane protein.
Sequence:
MTSQGPLPTRQHSFLGVKLHLPEASSSAKHVLYATGGPAKPKDGSKPLQQAGQPTRLAESLHPAMARKQDEARSGVPLRAQGPPAAEVRLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRGQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPDEGNQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGHGKRPNLESYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGSTLVVGLLVGMGYFAFMLFRRRLGNMILSLRPRPNYF
The following text describes a protein:
Function:
Involved in both the arginine and lysine biosynthetic pathways.
Subcellular Localization:
Cytoplasm.
Sequence:
MGRIAKYYREYGIRIVKGFMQYVWDDKGQRYIDCNTNHGVVFLGHANPKIVEAVKKQVEEIWAVPLNFATPARERFIEEFSKLLPPKFGVVFLQNTGTEAVEVAIKIAKKVTRKPTIVAFTNSFHGRTMGSLSITWNEKYKKAFEPLYPHVRFGKFNVPHEVDKLIGEDTCCVVVEPIQGEGGVNPATPEFLKALREEAQRKGALLIFDEVQTGFGRTGAVWAFQKYGVEPDIFTAGKPVAGGLPIGLAVAREDFGDVFEPGEHGSTFAGNAVVMAAAAAASRLLREEDVPGRAERIGAELAKALGDTGSRLAVRVKGMGLMLGLELRVKADQFIQPLLERGVMALTAGVNTLRFLPPYMISKEDVEVVHAAVTEVLKKAEQQ
The following text describes a protein:
Function:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development.
Subcellular Localization:
Cytoplasm. Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, myofibril, sarcomere, I band.
Sequence:
MALPTQQADELRLYQQTLLQDGLKDMLDHDNFIDCVLKIQGKEFPCHRLVLAACSPYFRAMFLSNLEEGKKKEIDLEDVDPDVMGKILHYIYTSEIEITEKNVQDIFSVANMFQIPSIFTVCVSFLQKKLCLSNCLAIFRLGLLLDCPRLAVSARDFVCDRFHLIARDEEFYDLSPDELIAVISSDSLNIEKEEEVFEVVLKWALKEKEKRAKALPIIFESIRFRLIPQDYIKNKVEKHELVKSDKELLKKLQMVKDAQEGKLPAAVKKTPSKASEGKDGEGVVNGDLEEEEEALPGILNDTLRFGMFLKDMIFMISDTGAVAYDPSANECFFASLSAQIPKNHVSLATKENQLFVAGGLYYNEENKDDPLSSYFLQFDHLDSDWLGMPPVPSARCLFGLGESDNSIYLIGGKELKEGEQTLDTVLCYDRPSFKWGESDPLPYQVYGHTVVSHDNLVYVLGGKGNEKKCLKRVCVYNPKKFEWKDLAPMKTARSLFGSTVHKGKILIAAGVTDTGLTNTIEAYDVKTNKWEEFTEFPQERSSLSLVSMNGTLYAIGGFATTENESGEFVPTELNDIWRFNEEEKKWEGILREIRYASGATFVAARLNILRLTKM
The following text describes a protein:
Function:
Highly selective calcium channel localized to the inner mitochondrial membrane, which mediates calcium uptake into the mitochondrial matrix. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates ATP production, cytoplasmic calcium signals and activation of cell death pathways. Sufficient to operate as a pore-forming channel without the need of calcium-sensor or auxiliary subunit.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MQLALRSRQATIITQGLLSGGRNWAHTYNNISSSPYRKPSFAIGRESRQTYGVSGCQSLIRGVQTGVLSKGKGPYGVTRRFTKSSLDSGDGRKTTRYEKQTEPREQGSHERNGSEEIEEEDEGTERLGRETRSRDSFGNSAEKGKLLTTPSRLLKLLIPLPTDHPKNVETIAILIHSQQPLSYLERLIQAELPMIKDENGTQRQPSISFIAYQFENHPIRPRKASSKKTKHSVDSSQEMEVEEVAVADDKEESQPPDEELDTYSSLQKPQPNGEGEQRYVRWSHATEIGDFIRDAARAGEFVVAIEGAPLGLDQVRITVPSFEERTHYLRMRLRKISDRIRTIADIKHECDQLAHRGAQRVALGGFGVLVSWWILVYKLTFETDLGWDTMEPITYLASLSTLMGGYLWFLYHNREISYRSALDFTINARQKKLYQLKGVDLQLWENLIYEGNALRREIKTISADYDTEWDEKLDERDERVVEALKKERDHQRRKGEDPDKEGRDLDK
The following text describes a protein:
Function:
Involved in efficient integration of the N-module into mitochondrial respiratory chain complex I.
Subcellular Localization:
Mitochondrion.
Sequence:
MALSFDLQDFILRARVLKLYRQALRTAKRAPEHARVELKHTIRQEMEKNRNCKEKQRIRFLISEGLERLKGLDEMLDMQGH
The following text describes a protein:
Function:
May function in mediating the binding of the antenna complexes to the PSI reaction center and core antenna.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Sequence:
MGWKQPHPIHTPGTTTTTLYSLHTCRHPRSKTKPSSLSPAASQPSSKLQARTATQPHHTKIMAGVNSSVVGLKPAAAVPQAAAAAASSQAKRVQLVAPEGRRAALLGLAAVFAVTATTGSAKAGIIDEYLEKSKANKELNDKKRLATSGANFARAYTVEFGSCTFPYNFTGCQDLAKQKKVPFITDDLEIECEGKEKFKCGSNVFWKWGEAK
The following text describes a protein:
Function:
Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MSKSNNKIGVVQLTILTIVNMMGSGIIMLPTQLAQVGTISILSWLVTAAGSTALAFAFAKCGMFSKKSGGMGGYAEYAFGRSGNFMANYTYAVSLLIANVAIAISAVGYADVLFGFHLTPIETCIATILVLWVATVANFGGARITGQVSSVTVWGIIIPVIGVSIIGWYWFDFDLYRAAWNPHGLPFFQALGGSIAMTLWAFLGLESACANADAVENPEKNVPIAVMGGTLGAAVIYIISTNVIAGIVPNADLANSNAPFGLAFAQMFNPTMGAIVMACAIVSCTGSLLGWQFTIAQVFKASADEGFFPKLFSKVTKADAPVLGMLTIVSIQSVLSLMTISPSLNKQFEALVNLAVVTNIIPYILSMAALGVMQKQLNVPVSQAKVANVMAFIGAMYSFYALYSSGETAVMLGSIATFFGWVLYGAIYRSQQNTPLKHA
The following text describes a protein:
Function:
Role in flagellar biosynthesis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Sequence:
MILETIFSFLEEKFLAWMCIFTRFTGFFLIAPFFSERAFPVVVRVLLGLFTSWLMLFTVDVSIPLNTPVLSFTLNLFFNFLVGFGIGFIVYLFLQAFNGAGYIFGFQIGFGMEEVLAFGEEETNPTGELVYFIALTVFVLIKGPVLLFEGLKDSIDVFPVNLTGVTDGFFSYIVGRSSDFFVLILKIGAPVIAFMLIISIVLGIVSRLIPQMNVFMVGLPLKVIIGVILILGMLPIWADMAQKISALSWNAIQELLGK
The following text describes a protein:
Function:
Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (By similarity). Degrades cutin, a macromolecule that forms the structure of the plant cuticle (By similarity). Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MKFFALTTLLAATASALPTSHPVQELEARQLGGGTTRNDLTNGNSASCADVIFIYARGSTETGNLGTLGPSIASKLESAFGRDGVWIQGVGGAYRATLGDNSLPRGTSSAAIREMLGLFQQANTKCPDATLIAGGYSQGAALGAASVEDLDSAIRDKIAGTVLFGYTKNLQNHGRIPNFPADRTKVFCNTGDLVCTGSLIIAAPHLTYGPDARGPAPEFLIEKVRAVRGSA
The following text describes a protein:
Function:
Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines. Degrades chitotriose.
Sequence:
SPFSLLSRKSDTARDQGEMMITARSHVSVTLGRSFSHPPSAPSSLEWDDVPTALPSSPHLSGTGRLARCAHKNHGKGRSDYRFIENVWPQPRIFLQNDTDVFPFDPNLVKVVTAFSCDIMTSSLAGFSKRMSLVLSHSGPTKAQPLELHVIVDDDKCPSTPQMGMVESYSLSVNKTHIVLQSMQVWGIVRGLESLSQLAFPSPIGLTMRVSHIEDAPRFPHRGLLLDTSRHFFSVRTIKAVIDLLAQNKFNVFHWHLTDNESFPFKPKAYPEMVKGAFDERHVYSQEEIKSIIAFARLRGIRVIPEIDTPGHTRSWGVGIPAITARCFDKLGKEDNDRAILDPTNPLTYDVVSALFKEIFTLFPDRFAHLGGDETSFWITQCWENNKNVTDYMKLWGMNTTSQLQQHYIDRLLNHLTARDMPRKQFIVWQELLDMGMKMDQAIGHVWTGNTKKEQMGNMAKIVKGGHFAILSSCWYLDHISWNIDVKEYYDCDPQDLENVSEMERGRVLGGEAAMWGEMVDESNALPRIFPRASAVAEKLWSEEKYTKSVNGDKVWPRLYEWSCRMAERGFPVQPGNGPGYCPFEYQPALPDLNY
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MEEASSSDILEAEIVGISFALATHRQIRLASISDAGINHASQLSNAFLGLPLEFGKCEACGATEPDKCEGHFGYIHLPVPIYHPAHVSELKQMLSLLCLKCLKIKKIKSTSSGLAERLLGVCCEEASNITIKDKSSDGASYLQLKLPSRTRLQEGFWNFLERYGYRYGSDHTRPLLAREVKEILRRIPEETRKKLTAKGHIPQEGYILEYLPVPPNCLSVPEVSDGSNSMSVDPSRIELKDVLRKVVAINNSRSGETNFESHRAEANEMFRVVDTYLQVRGTAKPTRNIDMRFGVSKISDSSSSKAWTEKMRTLFIRKGSGFSSRSVITGDAFRNVNEVGIPMEIAHRITFEERVSVHNIGYLQELVDNKMCLSYTQGSTTYSLRDGSKGHTVLKPGQIVHRRVMDGDVVFINRPPTTHKHSLQALRVYVHEDNTVKINPLMCSPLSADFDGDCVHLFYPQSLTAKAEVLELFSVDKQLRSSHTGQLILQLGLDSLLSLRVMMEQVFLDKASAQQLAMYGSRSLPPPAVVKSSKSGPAWTFFQILQLAFPERLSCRGDGFIVGGSDLLSFDFGVDALASIINGIVTAIMVEKGPKEALAFFDSLQPLLMEHLDPQGFSLSLEDLSMSREDMGVIHNLIVREISPMVSRLRLSYEDELQLENSIQKVKEVAANFMLKSYSMRNLIDIKSNSAINKLVQQIGFLGLQLSDKKKLYTKTLVEDMAQFYKKKYVSTSSSGDFGIVKGCFFHGLDPYEEMAHSVAAREVIVRSSRGLAEPGTLFKNLMAVLRDIVITNDGTVRNTCSNSIVQFKYELSSDNENQGLFEAGDPVGVLAATAMSNPAYKAVLDSSPNSNSSWELMKEVLLCKVNFQNTTNDRRVILYLNECRCGKKYCQENSAYTVRNKLKKVSLKDTAVEFLVEYRKQQAISEIFGMDICLHGHIHLNKTLLEGWNISMQDILQRCEDAINSLVQKKKKKAEDFKKMNLSVSECCSFRGPGSSKDSDMPCLMFSSYNATDPDLERTLDVLCNTIYPVLLETVIKGDPRIASANIIWNSPETTTWIRSRHASRRGEWVLDVTVEKSDVKQSGDAWRVVIDSCLSVLHLIDTKRSIPYSIKQVQELLGLSCAFEQAVQRLSASVRKVSKGVLKEHIILVANNMTCSGDMLGFNSGGYKALTRSLNIKAPFTEATLIAPRKCFEKAAEKCHKDSLSTVVGSCSWGKRVDVGTGSQFELLWNKKETGLENDDETDVFSFLQMVRSTKTADAYVSSPGFDVTEEEMAEWAESPERDSALGEPKFDDSAEFQNLLDEGKASESKWDNGSLWENGCSSGSEWGVSKNAGGEENTQSGWGKAANIEKEDASSGWNSKKDAQEATNTDSWGAWGSKTKDDAENATPNWGTKPAQNDSVVIENGEPSSDVWGPKAVSDKPWGKKNSETEPAPAAWGKTNSESESAAAAWGSTNKKNTGTESDAAGWGSTNKKNPETESDAGAWGSGAKNKETEPAPAAWGSWGKKSSEAVSGGADWGNRGKRVSETESGAGGWASRNPSLETQSGGATWGSRDKSKFETESGGAAWGSQAKNNFESESGSGAAAWGKKKPETESGGAAWGSQAKNKSEIESGSGAAAWGTWDKKKSETESGGGAWGSQAKKNSETESGAGASTWGAWDKKKPETESGGDGAAWGSQAKNNSETESGSGAAAWGKKKPETESGGGAAWGSQAKKNSESQLGAANWGSKDTNNSENGSDSAAWGKKKNSEAEPTSVAWGSWGQPSPPASDKDAQEDDGNPWVSLKATNSGEKEGNETSQWGVPNKRYPSAGSQSQGGGGGADWKRNRPPRTPGSESIMGPMFTATRQRVDMFTSEEQELLSDVDPVMRRLRKIMHQSGYTDGEPISDEDKTYVLEQILNYHPEKDAKLGPGLDFITVDKHTTFTESRCFFVVSTDGTKQDFSYRKCINNYLVEKFPNLAEEFIAKYFRKRDNENRDKNSQEATPPGEKESQTQPIDNGSQDSQPQSIGNEDGDTQPQSQAEDTQPQSQIEDTQLQSQVEESQPIGNGGEDYQTEPQG