lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Capable of resolving Holliday junctions. Specific for 4-way junctions. Seems to be important for the maintenance of mitochondrial DNA. Cleaves fixed junctions at the point of strand exchange. Cleaves after 5'-CT-3' and 5'-TT-3' sequences.
Subcellular Localization:
Mitochondrion.
Sequence:
MATVKLSFLQHICKLTGLSRSGRKDELLRRIVDSPIYPTSRVLGIDLGIKNFSYCFASQNEDSKVIIHNWSVENLTEKNGLDIQWTEDFQPSSMADLSIQLFNTLHEKFNPHVILMERQRYRSGIATIPEWTLRVNMLESMLYALHYAEKRNSIEQKIQYPFLLSLSPKSTYSYWASVLNTKASFSKKKSRVQMVKELIDGQKILFENEEALYKWNNGSRVEFKKDDMADSALIASGWMRWQAQLKHYRNFCKQFLKQ
The following text describes a protein:
Function:
Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
Sequence:
MKHILKILVNNHPGVMSHVSGLFTRRSYNIDSIAVGVTVNPEISSMVIVVKGDEATVDQVKRQLLKLPDVLEVEDLAYHDCVSRELVLLVVKLTETTRTEILSVCEVFEAKIADLTHSSLTIEYSGNSRKVNAIVEIMSKYGIEEIVRTGQIAIRYRSVGS
The following text describes a protein:
Function:
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
Sequence:
MTDAAGGRQEIWVEKYRPERLEDVVGHPDITERLQSYVDRDDLPHLLFAGPAGTGKTASSVSIAKELYGDDWQDNFLELNASDERGIDVVRDRIKDFARSSFGGHNYRVIFLDEADALTDDAQSALRRTMEQFSNNTRFILSCNYSSKIIDPIQSRCAVFRFAQLGDDAVAAHLREIAETEGLEHTDDGIDALVYAADGDMRRAINALQAASATGDSVNEETVYAITATARPEEIETMVTEALGGDFAAARATLDDLLTNRGLAGGDIIDQVHRSVWEFDVEEAAAVRLLDRLGEADYRIAEGANERVQLEALLASVALNAE
The following text describes a protein:
Function:
Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
Domain:
The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.
Sequence:
MDGTMDSNGVEEEENDDVRFWRYIKEGNSSFVIGHKKKHIVYQLWKQDAKDALEKNSRKEECWAKINYIKNCLQPALGSYSSIPKCISVSPHFIDSVSKAFESQRPLKRCHQVIDPYQTSVLCSPNFCFLDNIGQKGRSTLTIELKPKRGYILTHHLPSIEIEDQLVCLFCMQQILKRKRGVWDYTSKYCPIDLFSGVPERMRHALESLFKTPQNNLCIFKDGEIIYPREDKSLPSQDDQEDITMAIQSWFECEEGSLSSDNTRPHVPHTFSKSACIQDVISLVIQALCRSDNASTFQEITQGSSPWIPCLEGQQHGLNHDEEVSSCRLAKDCVLGRILTMQRMDTHGIHVIHKVYQRYMEHLSHYPEQKEGLRITDPCLTSCLTTNVKQRLSDDEISSLPIQECVSLLNAYMMSRTARDCSILITFKPADPSSTMDDDMVSLKEQRFHVACNLVDLDSKLTTKIPYYHKLEQLISETYSSR
The following text describes a protein:
Function:
Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly.
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MGSLSGLRLAAGSCFRLCERDVFSSLRLTRSSDLKRINGFCTKPQESPRAPSRTYNRVPLHKPTEWQKKILVWSGRFKKEDEIPETVSLEMLDTAKNKMRVKISYLMIALTVVGCICMVIEGKKAAQRHESLTSLNLEKKARLREEAAMKAKTE
The following text describes a protein:
Function:
Plays a role in transport between endoplasmic reticulum and Golgi.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MLFRAQLRRFDAFTKTVEDAKIKTAGGGLISIISAVIVFVIVFLEWKNYQRIVVQPEIVVDPSRNERMEINFNITFPHVPCHYMGVDVMDISGDFQQDVQHSVTKTRLDKYGNIIAVIDSDIGSATDESAMDKDGEVTCGDCYGAGDAAPPETPGCCNNCKAVRDAYARKQWAIGDYDAFQQCRDENYKAEHASQKGEGCNIAGHLFVNRVAGNFHFAPGRSFQTQQGHLHDLRGYEEEQEAHDMTHMIHQLSFGPPIKPSAEHTDPLDGHFKNTDDALHNYAYFIKCVAHKFVPLDPADPTINTNEFSVTQHERSVTGGRENDNPSHLNRRGGIPGVFFNIDISPMLVIQRQIRGNTFGGFISNVLSFLGGFITLTTLVDRGLYAAELKMKKN
The following text describes a protein:
Function:
Potential transcription factor that may play a role in the regulation of genes involved in cell cycle G1/S transition. May bind to regulatory elements of genes, including the promoter of the transcription factor FOXO1.
Subcellular Localization:
Nucleus.
Sequence:
MLSLLSLPSTPSTPTYLQIGRNPAEADVFIDSKVHPALISRRHAEIRVSPDGRGNVTYDITDRSVNGTYINDIRLQPRTPHRLQEGDTITFGHLKAGTVQPGQRSVQAGSEFKFKFEQCPRPAGDVDTRTDSETPTTLSLPEKSTEPGDVGRGRQLFPSVPSPDVLHDISNWVQKSKLVHTGPAEKGGQKETGTAASSSTGLSQFSDEDNDSDSEIFSIAATLQIPSDSDSDSDIFCPTEKPPTSGDKSLPKVRSDFESPRAVPMATVVPMATNVARLSQSPIVNISDSKDSSTVVNTKRKRRPPAGKTVAAVKRRKPVKRKRSGDREDWGPCDSFDCSRPEGDMLSWVQCDQCEAWYHVACAGCDYDTVRQETAAFNCGCL
The following text describes a protein:
Function:
Responsible for physiological and behavioral changes in mated female flies. Associates with sperm and localizes to specific regions of the female reproductive tract, including the sperm storage organs. It accelerates sperm accumulation into storage but does not mediate the entry of the first sperm into storage. Once sperm storage has initiated it seems to act as a guidance factor helping subsequent sperm move into storage, a corral concentrating sperm around the SSO entrances and/or a trigger for responses within the female that accelerate storage of sperm.
Subcellular Localization:
Secreted.
Sequence:
MWTLTCQQFIALILLGTLVPSESFLCKHCFRKNLEKVHESFRDILSPPIFGVNPQPLIEVQQPKVTPKPESSQVIHVHQPQVILKPIYYPKVDTISTKNQIGIHGPYSQYPSLLPSANLLGIPNQQLINAQDVLSDKDQKQTQVQNNNLHIRFGVSALREGRNNPSLETISRDKVDKISPALQLQLLRYADSQSQSQTQSQSASQSESNASSQFQAQEQSNRLLENPPVSESQSQSESQSQSESQKQSQSQSQRQQQIQTQLQILRQLQQKSNEQSAAQSASQIQSQRQSDSQSNLQLQEQSQSQSEQGKPIQSQIQILQGLQQKELDDKSASQSQSESKTRQEQQKQLNLQQLEELSSSLSQSRLGLGQQIQSQLQKNQLDKQFASQFQSQSKSQLEQQMQLQLQSLRQLQQKQLDEQSASQSQPQSQVAQQIQSHLQLLRLLQSRLKTQSALKSDLEQQILLQLKKLTEVQQKQLAEQPTLRPSSKSQSPGQLEQQILLQLQNLLQFQQNQLKSDTQTQSQLQESKSNSLSQSQSQSQEQLQLQRDQNLRQLEQIKLEMQNIRELLQKGKSELQTQSDSQRRIHELYQNILQLNKEKLSYQLKQLKLKELEDQKKSQAEISKGSNPSNLFIIGQLPSEGKPAPGNQGPSIEPKLVPQPGSLDKLPSGGGLIGKPASTGLYILSPDFNDLSDYRDQFRLQQELKKHQNILSLLQRRQNDIKKQQNAQLLLGQQQKEQQAQESINKQQSSSAGSSSQTKLQQDIQSTGAQGSQQGLQAGSTGLQTSSLQGTESSASQSAALQRLKEQEQLRIQTENDQKTSSSSSHSNSQNSQSSSSQSSQASQSEAQRQEAGNRNTLLLDQSSSKTQSESKSESSSQSSSHSSSQSTSNSSSNVQSKLQGESQALLNNLSG
The following text describes a protein:
Function:
Cell surface proteoglycan.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
STCQGVRSGWNCVAVVTHSGRKPAPQISGGETCGEVRRTFRTRALGPADMVPIMPAEVTGLSVCQSVGPTCCTPSMEEKYMEASVRELRELVKRKTTPLEKHFRAIAKKFRARTLITYIEQPDHRYFLDLYRDCSIQSCNDITSKFAQVGLITDLSNNINLTRILSSLFILSLEDEIGLKIPKEKIECALTKATSYLTPYAVLKSKFENLLNPVGVFLKALTVGLRAAEVSRRIATGGPCIDAITKMRYCSHCYGYTLIKTCPGLCHNVVRGCLVGMAELDMFWKYYIVSINNMANKLVNTEGGFDVYFPQILRNISLIVQSVTYNQESVTLQCKLLSRSQVVRSNKMNINARFTLKESPAHSVKTLNKPRFIDLVIINLHRSLADSRRRFADELNTTRDFFASFSDDLCSSSDPVSFQVSNYGHCWDGVKMANSYKKPTPDKGIEGQLQNPEVKVVTLKRDVQTIIEDVRTITKELMKSSGSEQIPSDLLQRPSYITSHLQTDEIPCDDEDECFDNGSGE
The following text describes a protein:
Function:
Alpha-amylase that cleaves starch into oligosaccharides, the first step in starch degradation (By similarity). Endo-acting enzyme which prefers a linear polysaccharide to branched polysaccharides hydrolyzing alpha-1,4 glucosidic bonds efficiently. Also has transglycosylation activity, but does not act on alpha-1,6 bonds. Higher activities of 100%, 79% and 67.8% against amylose, soluble starch and amylopectin, respectively. Lower activity of 22% against glycogen and faint or no activity against alpha-, beta- and gamma-cyclodextrin.
Subcellular Localization:
Cytoplasm.
Sequence:
MHHPGPPRFVATGDEVELAPRDPDPTATYTWRLTQAPAQSTVSLGDDPVEHFVPDAPGRYVVRLTAPDGEHDLTVRAFPGTLESSGTHTSGRSGGHSGGVSGGRSGPGRSGSGEYTQAGDGSDGGGGGQPRLTLRPDIEGDEAVVRADCSPHPEGTETAADLAVEFLLDDRDDVDADAVTRDGTALRIPLDALPERARIHAVAVGNHGYSVPDAVEFTRGGDGVETVTSGAGVAARRPYDAPAWAEDSVIYEIYVRTFAGERDESPFDAITDRLDYLDSLGVDAIWLTPVLQNDHAPHGYNITDFFEIASDLGTRADYERFIEAAHDRGFKVLFDLVCNHSARTHPYFESAVEGPDADYREWYEWRSDTEPETYFEWEHIANFNFDHLPVRRHLLDAVAQWADLVDGFRCDMAWAVPNGFWREIHDYCKDRDSEFLLLDETIPYIPDFQAGLFDMHFDSTTYAALRQVGGGGDAEAILGAIEGRAEIGFPEHASFMLYAENHDETRYIVDYGREAAEAAAGALFTLPGAPLLYAGQEFGQRGRRDDLAWDHADETLQSFVSDLASARHDQPALSADADLVRIPYEVRDGPSDRVVAYARTTENDAAVVVLNFGSEPTTVGLPAGTDGTDLVSGEYRGAAGDGDATVTVDSVSVFPADENDLRQ
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Plays a role in sustaining courtship behavior in males, possibly through the reception of a stimulating arrestant pheromone.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDFQPGELCAYYRLCRYLGIFCIDYNPTKKKFRLRRSVLCYIVHFALQAYLVGCISVMVTYWRRCFKSELTTTGNHFDRLVMVIALGILVVQNAWLIWLQAPHLRIVRQIEFYRRNHLANVRLLLPKRLLWLIIATNVVYMANFIKTCIFEWLTDASRLFVITSLGFPLRYLVTSFTMGTYFCMVHIVRLVLDWNQSQINAIIDESADLKMTSPNRLRLRVCLEMHDRLMLLCNDEISLVYGFIAWLSWMFASLDVTGVIYLTMVIQTKKSIVLKLITNVVWLSPTFMTCAASFMSNRVTIQANKTAKMLTKVPRTGTGLDRMIEKFLLKNLRQKPILTAYGFFALDKSTLFKLFTAIFTYMVILVQFKEMENSTKSINKF
The following text describes a protein:
Function:
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
Subcellular Localization:
Cytoplasm.
Sequence:
MIVKEVLNEELLTLAEVKDILSRIADERREQGIEVAYSFRKALHHAEQFSKINGEKSRELVNKLLELEKMKPVIAVRIADILPQSRDELRSIYAKEKYTLSNEELDQILDYVFEAME
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
LQYPEWYLAPNRCLVSNCGVNKMSNEELVGQNHGMEGEACIGGDVTFNDVAIDFTHEEWGWLNSAQRGLYKDVMVQNYENLVSVAGLSITKPYVITLLEDGKEPWTVEKKLSKGMIPREWENKELSTKKDIYKEDSLQTVTIENVLKQSYEFSNSTKNLEHIEKLEGKPGIHVEHFRPATLTSRESPTGDRNSHKYNILKKNLPKIQLNGGKKLLNSNKSGAAVNQSTSPHHTCNRGTFGKQSIRNRHWRIHTGEKPCECRECGKTFSHGSSLTRHQISHSGEKPYKCIECGKAFSHGSSLTNHQSTHTGEKPYECMNCGKSFSRVSLLIQHLRIHTQEKHYECHICGKAFIHRSSLIHHQKIHTGEKPYECRERGKAFCCSSHLTPHQRIHTMEKQYECNKCLKVFSSLSFLVQHQSIHTKEKLFECQKCRKSFNQLESLNMHLRNHIRLKSFGHRSSLLQHHRIHTGEKPYECIKCGKTFSCSSNLTVHQIIHTGEKPYKCNECGKAFSKGSNLTAHQRVHNGEKPNSVVSVEKPLDHMNHYTCEKSYRRECI
The following text describes a protein:
Function:
May function as a co-chaperone.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVKSVLVAYALWAVGGPLGLHHLYLGRDSHALLWMLTLGGFGFGWIREVIRIPAYVRAANKDPEKERRKENNRVPPPPGPVRFAGQVCVGMYFGAVALIGLNSLSFFYLIVLPLSVGAGVHLVSSVGEQTSDLKKTLTACLMMSPVFYGSTLSPLPISLAASITASQHRRFKPPQTTSSTQKLGPRLYKLALAWLAFSAPIGYCIFYNTTATLYYISDSIAALLDIFWFLPWLRGLLEYILLIPYRILCALTGGGYQEEAWRKILEILLKEYTEKEKQALQVFSLKSDASLEEITRSYRELAKTWHPDHNPSQEAEAMFLKVQEAYEVLLRWHKPQRFQ
The following text describes a protein:
Function:
Required during anaphase to drive sister chromatid separation to promote flux by actively depolymerizing kinetochore microtubules at their pole-associated minus ends, thereby moving chromatids through a 'poleward flux'. Involved in asymmetric cell division of sensory organ precursor (SOP) cells by playing a role in the asymmetric localization of Sara-expressing endosomes to the pIIa daughter cell but not to the pIIb cell. Klp98A targets Sara-expressing endosomes to the central spindle which is symmetrically arranged in early cell division. During late cytokinesis, central spindle asymmetry is generated by enrichment of Patronin on the pIIb side which protects microtubules from depolymerization by Klp10A while unprotected microtubules on the pIIa side are disassembled by Klp10A, leading to the asymmetric delivery of Sara-expressing endosomes to the pIIa daughter cell.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Chromosome, centromere. Note=Localizes to mitotic centrosomes, spindle poles and centromeres through metaphase. However, the centromeric localization diminishes markedly at the onset of anaphase, leaving the majority of the protein on the spindle poles. Concentrated around the minus ends focused at the poles.
Sequence:
MDMITVGQSVKIKRTDGRVHMAVVAVINQSGKCITVEWYERGETKGKEVELDAILTLNPELMQDTVEQHAAPEPKKQATAPMNLSRNPTQSAIGGNLTSRMTMAGNMLNKIQESQSIPNPIVSSNSVNTNSNSNTTAGGGGGTTTSTTTGLQRPRYSQAATGQQQTRIASAVPNNTLPNPSAAASAGPAAQGVATAATTQGAGGASTRRSHALKEVERLKENREKRRARQAEMKEEKVALMNQDPGNPNWETAQMIREYQSTLEFVPLLDGQAVDDHQITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLTKFLENHKFRFDYAFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCKNGIYAMAAKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLSDKQKLRVLEDGKQQVQVVGLTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQGSTKIHGKFSFIDLAGNERGVDTSSADRQTRMEGAEINKSLLALKECIRALGKQSAHLPFRVSKLTQVLRDSFIGEKSKTCMIAMISPGLSSCEHTLNTLRYADRVKELVVKDIVEVCPGGDTEPIEITDDEEEEELNMVHPHSHQLHPNSHAPASQSNNQRAPASHHSGAVIHNNNNNNNKNGNAGNMDLAMLSSLSEHEMSDELIVQHQAIDDLQQTEEMVVEYHRTVNATLETFLAESKALYNLTNYVDYDQDSYCKRGESMFSQLLDIAIQCRDMMAEYRAKLAKEEMLSCSFNSPNGKR
The following text describes a protein:
Function:
Has oligopeptidase activity and degrades a variety of small bioactive peptides.
Sequence:
MSQGLPLREDVPVSETWDLVDLFKDDQQYYESIDALVQQANQFHHTYATTLNSIEQINTALAELENILIALDRLSNYAELRLSVDTSNIEAQVLSAKLSTTYGKIVSQLSFVESEILELPEEILQQLEESCPYQHYIKQLIKQKPFQLSASVEQVLATLSPTLNSPYDLYGTTKMLDITFDSFEHDGTTYPVDYATFENDYEDNKDPEFRRKSFKSFSDGIRKYQHTTAATYNMQVQQEKIEADLRGFESVIDYLLHSQEVTRDMFDRQIDMIMRDLAPVMQKYAKLLQRIHGLDNMRFEDLKISVDPDYEPEISIEDSKNYIFGALSVLGDDYTNMLREAYDQRWIDFAQNKGKDTGAFCASPYFTHSYVFISWTGKMAEAFVLAHELGHAGHFTLAQKHQPYLESEASMYFVEAPSTMNEMLMANYLFNTSDNPRFKRWVIGSILSRTYYHNMVTHLLEAAYQREVYHKVDQGESLNAPTLNEIMLNVYKQFFGDAVDMTEGAELTWMRQPHYYMGLYSYTYSAGLTIGTVVSQKIKNEGQPAVDAWLETLKKGGSVSPVELANIAGVDITTEQPLKSTIQYISDLVDEVEKLTDEIEQANN
The following text describes a protein:
Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Sequence:
MPHSHCHSLRSFHNAPPLSAITHGTNPITFEDRLCLPSSFHSRTCFLDNFQETCNETTSCQMTNCEQDLFTDDSCVQSNCFPGVVQTTYSNSRPCERTACQSESSSAGLACVSQPCQSESTQQMGFVAQSCQPASLKGNSCPPKTSKSKNFETLERASSQCQCQSQNPESSSCRPLVNVAPEPQLLESSPGVEPTCCVTGGSQLPSK
The following text describes a protein:
Function:
Functions as a receptor binding protein (RBP) and probably mediates the attachment to the host capsular exopolysaccharides (Probable). Displays a depolymerase activity that specifically degrades the K47-type polysaccharides of Klebsiella pneumoniae capsule, which allows the phage to reach the host cell membrane and bind the entry receptor.
Subcellular Localization:
Virion. Note=Tail appendage.
Domain:
The N-terminus anchors the RBP to the virion (By similarity). The central part and C-terminus probably binds and degrades the host exopolysaccharides (Probable).
Sequence:
MDQDIKTVIQYPVGATEFDIPFDYLSRKFVRVSLVSDDNRRLLSNITEYRYVSKTRVKLLVETTGFDRVEIRRFTSASERIVDFSDGSVLRASDLNVSQIQSAHIAEEARDAALMAMPQDDAGNLDARNRRIVRLAPGIAGTDAVNKDQLDTTLGEAGGILSDMKDLEGEIHDYIEKFADDTALVRGVAWVYNLGSADGGETVITINKSTRTYAVPYIEVNGSRQEVGYHYSFDLETQQITLATPLKAGDFVMVMTTESQLPVETLLASSVGAASIGTATGETVEERLTRLYGHFVHPETYGAVGDGITDDRVALQRSLDVAYENALNGTGPSTVRWSGDYMVSLNPNSLGVSGELAAGRSALCIRPGVSIEGKGTVRLDPSFTGSQSGAVITNWAGPADDCSIKDIRIYGGKDVATGTGITGILILDSQRVVISDVKVLNSTAGGIYLRKGATEGLYGCSFSKVSGCTVDNAGYIGIQMERPYDNTVIGNTINRCEDNGIDVFGNVNDATVTGIAQSTLITGNNIRDVLNGVFIESCGNTNITGNYIADFRSSGVIYNRINSAANDNSLTSNVLIGASGASAGVSFKNSVGYCTVASNRIQNSDYGIRCVGGGITGLNILPNTMKNIAKTLLFVEARNNGLVKSRMSTQFYEGAQVGGIPSNTSPRGVPHRFPSRLSYIVDIQPFWATEQGTREDNFERAKGTLASITGWGSKCALYDTIVAGDTVVSLNSSSVAVGEYLEINAEVYKVTSVSATYAVVRKWTGSDYTAGDYAAVIISNPSYIIRRVQWGEQ
The following text describes a protein:
Function:
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subcellular Localization:
Mitochondrion.
Sequence:
MVSEPAHSKWVAVKANIATREGPTNCGSAFLADYTSPFDATVVDRLKQHGYRIGLKTNMDEFGMGSFGLHSAFGSVTNPALDATAQPRVAGGSSSGSAAVVAAGQVPLALGSDTGGSVRVPAAFCGIVGYKPSYGRLSRWGLVSYASSFDCVGVLASSVDQAEAAMQVMQGHDSRDETSLNVDWAAQEAQDTPVRRVGVIQEAVIHELAPAMHDRWELALQQLAQQHCLEIDTVSVPTLKQALAAYYMLVSAEAASNLSRYNGLCYGAQSGAPETFDGFFDMYSSNRTQYLGDSVKQRIMTGNHILSRGKFDSYYLTAARVRAQLTLELQRVFERVDVLVLPTTADVAPTIEAARNIEPVQEYATDVYTVPFSLAGLPAISVPCGRDPQSSAPMGLQVVAPRQLDHRAAHVARLLEAMSWPN
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MKNLVPRTQSNMIISLQASALLEGEVGVGSPPKEGNPTQESIPALQPFIQLQGSSEAISFSQLGRKDVSDVRAMRKHKGWSSMGDVVLTRQEKDIALAPVSNIEEKEGGTSGVLTARFQESLTFKDVAVEFTWEEWRHLDPAQRALHRNVMLENYENLVSIEGKIRLEMKEMTAELSLSGEETQRQRCIGDGACDSTWRENLDVHQRIHTGEKRFECNHCGKAFRSRNRLVTHQNVHTGEKPYECNQCGKVFTYESRLNVHQRIHTGEKPFKCNQCGKAFTHKSGLTVHQRIHSGEKPYECNLCGKAFSQKSSLTVHQRIHSGEKPYDCYRLSKILSQKSTLIFSQPLPSQ
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1). Cap1 modification is linked to higher levels of translation.
Sequence:
MADRKSDEGEDEYQHKEQMVTNRTSSFQPKSTEDSISKLAKMRAADRREEFMEERASFSAVKRGYQAGDDEEDDFTAEEEPPAKKPLTVAERLMAAMGHKAGEGLGKHGQGISEPIASSTQRGRTGLGHNAGKATARDFNEVWDETTEEKTVVERVEWMTDIEEEKRAEICEQLKDDKWMVIGKEKRTIDDETKFCSQQSITEMIEAKNVFDLMSDKDLREARTRANPYETIGSAFFQNRAAMKTANMDKIYDWILSRENTENDRFLLKNPLQESQTAENVDRSEDLFYFADVCAGPGGFSEYMLWRKGFYNAKGFGFTLAGKDDFKLFKFTASSQYFFETFYGTKDNGDVMDPVNIDSLEAHISRGTSGLGVHLMMADGGFSVEGQENIQEILSKRLYLCQLLVSLCIVREGGNFFCKLFDIFTPFSVGLIYLMRVCYQSVSLHKPHTSRPANSERYITCKGLRKEFANVVKEYLKRVNRKLDELKNKKSHDDVTDLMPLDVIEADQIFMDEIIRHNEFLANRQTLYLRKYQSFAKNQGQFDKDQGNLRDECLKYWQVPNKQRPRGGDRGNRHDNMQRLNPLQVYGKYCKKVCGESEIGNTFPDFSLNCLDAPLPNIPYEEYRFVPLASSGSPNLLIAAGDSAFIFRSGRFESISADHIRIPENTILLVDWAEEVVRGDGNRIKISSEPQVVRIIDAAVLFGDDVSNLPYEERMKAAEKFVAALKQTNRKVKKGWGHRAEMIKPHLKICAKTYSLAELDEFRSNLEKLEHNRELAVLFTEGEFTFRCQALRFTRIIKQEWRMGWSKSQQKPYAHSQEHQNAGSIPVELWAEKSIYSSFWDSVICLNKDKKKLMEAMEHTKGKCPIPSSIWSWKACIRTPYGPEKILNYPEPFEGKPTIAALKAQIENTDLIVKRVRN
The following text describes a protein:
Function:
Toxic component of a toxin-antitoxin (TA) system. An RNase.
Sequence:
MGASQRALLDTSVLIEILDKGRLSLLPKDPYLSVISIYEYIRYKRDRHFYKERLEEAFSVLGLTNKVIERAAEIFASLKARGVVVSDNDVFIAATAVAYGLPLITKDRYFLKIKTAAGLDVVFID
The following text describes a protein:
Function:
Ammonium transporter probably involved in ammonium uptake from the soil.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MASAMTCSAAELFPHLGSSANATAAAEFICSRFSAVSEYLTNTTYAVDTTYLLFSAYLVFAMQLGFAMLCAGSVRAKNTMNIMLTNVLDAAAGGFSYYLFGFAFAFGAPSNGFIGKHFFGLKEFPSQAFDYSYFLYQWAFAIAAAGITSGSIAERTQFVAYLIYSSFLTGFVYPIVSHWFWSGDGWASASKTDGNLLLRFGVIDFAGSGVVHMVGGIAGLWGAFIEGPRIGRFDRSGRSVALRGHSASLVVLGTFLLWFGWYGFNPGSFLTILKSYDHTIRGTYYGQWSAIGRTAVTTTLAGCTAALTTLFCKRLLVAHWNVVDVCNGLLGGFAAITSGCAVVEPWAAIVCGFIAAWVLIGFNALAAKLKYDDPLEAAQLHGGCGSWGIIFTGLFAKKEYVNEVYPGFPNRPYGLFMGGGGKLLGAQVIQVVVIIGWVSVTMGPLFYLLHKFKLLRISRDDETAGMDLTRHGGFAYIYHDEDEGSSMPGFKMTRVEPTNTSTPDHQNRSVNVVV
The following text describes a protein:
Function:
Paternally sperm-supplied factor required for embryogenesis. Plays a role in preventing polyspermy possibly by promoting the formation of a continuous and cohesive eggshell chitin layer.
Subcellular Localization:
Cytoplasm, perinuclear region. Note=Localized to the perinuclear region of sperm.
Sequence:
MSDEEIDISTALNNKTTPKKKSLKRNSNSQEGYESPEEREIVYPSVFGAIGTPMAKSDNAKEWDEWKEKERKKDKAEWKRYLRSKWDMTQGHLPLVSDSEFLKGRKEHKEYNSKARMDILDGLDEVNEGFFNCGKGAAMNIRYNDKNVSKKGAKKFVATVETAMKKAGNPTMEQMMTDDLDEDEARAEAEWERQREQRKLASRAYDAAMDEREDDAKYVPWDEYCQEMEELGKELKIGEKHYKKWLEKKMDENKVTHKFNAYQLDLKCLDEDAFSNKKSLKSVVRNVQKFYRKMREPKK
The following text describes a protein:
Function:
May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). May be involved in the specific O-acetylation of cell wall polymers (By similarity).
Miscellaneous:
MISCELLANEOUS: Contains 2 motifs that are conserved in esterases, but it is unlikely that this protein belongs to the catalytically active pectin esterases.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MGFTSRGNPSFLFFFFFFLCLSTVSAYINSTSSNNDEVRRELASGRCNWFRGNWVYDVKYPLYDPYKCPFIDPQFNCKKYGRPDNAYLKYRWQPSSCSLPRFNGLYFLRRMRGKKIMFVGDSLSTNMWQSLACLIHSWVPNTRYTLIRQKGLASLTFEEYGVTLLLYRTQFLVDLNVEKVGRVLKLDSIKQGNMWRGMDVLIFNSWHWWTHTEHIQPWDYMEDGNRLYKDMNRLVAFYKGMTTWARWVNAYVDPSKTKVFFNGVSPTHYEGKDWGEPMNSCRSQTQPFYGRKYPGGTPMAWVILNKVMRRLKKPVHWLDITGLSQLRKDAHPSAFSGNHPGNDCSHWCLPGLPDTWNLLFYSTLFSS
The following text describes a protein:
Function:
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity). Required to maintain the reduced state of SoxR. Probably transfers electron from NAD(P)H to SoxR.
Subcellular Localization:
Cell inner membrane.
Sequence:
MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEILPQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQEITPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCISLQPVAETPDSWKWDLNTIPVRIIPVEHHA
The following text describes a protein:
Function:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Subcellular Localization:
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Domain:
The tau/MAP repeat binds to tubulin. Type I isoforms contain 3 repeats while type II isoforms contain 4 repeats.
Sequence:
MADPRQEFDTMEDHAGDYTLLQDQEGDMDHGLKESPPQPPADDGAEEPGSETSDAKSTPTAEDVTAPLVDERAPDKQAAAQPHTEIPEGITAEEAGIGDTPNQEDQAAGHVTQGRREGQAPDLGTSDWTRQQVSSMSGAPLLPQGLREATCQPSGTRPEDIEKSHPASELLRRGPPQKEGWGQDRLGSEEEVDEDLTVDESSQDSPPSQASLTPGRAAPQAGSGSVCGETASVPGLPTEGSVPLPADFFSKVSAETQASQPEGPGTGPMEEGHEAAPEFTFHVEIKASTPKEQDLEGATVVGVPGEEQKAQTQGPSVGKGTKEASLQEPPGKQPAAGLPGRPVSRVPQLKARVASKDRTGNDEKKAKTSTPSCAKAPSHRPCLSPTRPTLGSSDPLIKPSSPAVSPEPATSPKHVSSVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAASPAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMPDLKNVRSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
The following text describes a protein:
Function:
Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
Subcellular Localization:
Nucleus.
Sequence:
MLAGRESLIRLVGKRRRNLSREFLLLDPLQHPPLSPSPSRPNDAGGVSSSERGSTPVDSGGGLGENGNEVVWVECPVCRKLIRGTDYSVNSHIDLCLVRGTKRTLTQRTILDFCSRSTGGIELDKSETVQKNRREQEIVHDDKSVSDSECVLIETDLSESSRRREVENEALLGKITQVCVNNSDVPCSSPSCSPSSDNDMFDFHMHISDDDLSATKLETVIVGRRYHAKHEPSPGATVYILRDPENVKDNYALKVTCSNSGEEQMLGYLPKDLSKYLSPLIDQYNLKFEGSVISCPKDEHAIIPVQINCQRKVPYNEMIPDDIKHLKLLWRNALQVVEHGKTLNPNIPKYHKNFLVMIQEVLKQHVHLFMENEKLFLENFESLSHDGQRIFIRLYTRKGPWFRTSNISYPEVQDSHKAIKELQLAGYVCPFLYREESFKSDISEVLSLLTVSDLREISSATLLKGLVNWLSASYKGGTCPLLPEKIMEKAGTCVKVSSDAELLLWRVQRLFFLNGEHDLSAFLLVDLGMVKYPSYICNVSQPVFRSRNDLLAYEQAIAVAQILDESIEENNQEWVIRCINFSDSCISLLPISSLTQFFHFSSSWVYSKVITLGISYYEREKKYGNAVKLLKGLLKKIVCDGKRGYWNLRLSIDLEHMKYMNESLLVAEEGLLDPWVRAGSKLALQRRVLRLGKPPRRWKKPTFAKFIDRKIQDVHVIGRPLNCETGTKNRYYGYDGLQCGVENLALQHYAGEGGGWKGIHAESGIWMTIFGLLFWDIIFCNISDVFHTRFQIAPLDFGTDHFYLSRRDLIDSQLINICNGMAEEILICSYESHQGISCMGVHWDQYCLSDLRAIVACIGCNCLASLCRHLAQDYRNWSHGMPDLLLWRFNNGDDGIKGEAKLVEVKGPKDRLSEQQRAWMLTLMDYGFNTEICRISPTPTPQ