lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.
Sequence:
MEFHLNINRFFQNPITKFRGQDIARCDPELWKVVDYVGEASRVAQNLHRPVTIAHSFVNSNQTLYIMTDASANKGNGAILGMLKIGPKKLFLLDKKGFQNELDPLCVLDFYIHESCQRKGLGKLLFAHFLEDEKLHVHKIAIDRPSEKFLGFLQKHYGLKNFIPQVNNFVIYEGFFDNDDHQASSKPSAGRTNSSSLPSRCNSMMALNAATEQSINFRTRGKQSVTECLYDETISNQNDLWRTNSLVNVNTSPTAQISVQHQPKPFATDTASKFGHHRLW
The following text describes a protein:
Function:
Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. May act by regulating the catalytic subunit PIGA.
Miscellaneous:
MISCELLANEOUS: PREY and PIGY, 2 apparently unrelated proteins, are respectively the product of an upstream and a downstream ORF contained in a single bicistronic transcript.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MFLSLPTLTVLIPLVSLAGLFYSASVEENFPQGCTSTASLCFYSLLLPITIPVYVFFHLWTWMGIKLFRHN
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MYTPVSETDPMLMSPSGGKERRSPPSSAVNSLRLEPPPAKCNDAFFAVFFLANVVILGILAFWKGIPALQDDMSKNRSDGRIPRGHSVAWTMIGLLCAIGTVLSLAWIKLLMSYAESMIRVALWLNVGMVLVFAVTTFSVNPWAALVFLAMAAINVWYIYAVQNRIGFASANLKAACAALKEHSAVFGLAFFLVLQQLAWMALWGVASLGMHQIFVDADPDCDREIDLASRGRSHGGLCVGLPAYLAMFYMLVSVYWGQQVLQNILTCTTAGVVATWWYQPNAQKATVGALYRSVTTSFGSICFGSLIVAVLQALRTMADMAKRRANEENNGGLACLACMAECILSCLANVMEYVNQWAYVYVGVYGYPFRTSGKAVMDLFNNRGWTAVINDDLTSGALSFGAMGVGVVTCCIGLLMVRFSPMEWFTALGSRMSVYGTMALIGFMVGISMALILAHVIIAALHTIFVCFAEDPVAFNRNHPKEYNDLVAGWRQFHGDALLSAYGEAV
The following text describes a protein:
Function:
Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation.
Subcellular Localization:
Nucleus.
Sequence:
MRPLSSNIEDDNPNNGSDSDDGADGESKKRNSSDTSSNESADESSSEDSNIGNKLGGTVPVAGGPMAGGMNGNGVSGAAGEGATGAAGTGNGNGNSSPVRRPSDWSLLNFLKQPTSNSQQVPTNESAPHVGGGAVGDRTSAHHHHQHHHQNLHHTHEENSVSSPLRQQRLSGLSEVVQGFIASPIADGRSATVAPVKNEPLAPLDDDHLSNASSNASNSELPAGQGVSLSSGINAGSSSSSYVKQEPYPSENSASPPGIKSEQKDDGADRLSLSSPAKSPELQHHVGNYSLHHRQQQHLFNDSVEQVDVICALQEAKEFSLIKPISSMSDSDSDDAEIPSMVGGDLEQQHRVNLHHVNTHMSHQPDGEPVAAGNGVVLASATANAVKKKKWKRKLIAGTGNERETRDSSTSSSEDERYGAARRSRSRSFEKEKTHLKPRGRVRKGHSGNTHGSGGGGGGGTTSAASSARYSDADSITSGGGHRSSKTSSHGSTPTKKGSASSAINSLPYAHGDTGAAGIMSPPISIPSVDGIVLSKKANSRKPRSSKILSSETVLSTESSSSSSGSSAEEDGVASSGESADSNSGHDRSTPAPADPVVPVTKTKKHKSKKKLDKMAPADVLTSNISAGKGNGPITNDVSMKNRPINGSGSSRSNNNYHLHNLSSDSNDERPSLITSPFQGSGGRLGDVATSGNLPKKPHKLSISQTSVDEEESRVLNSNGNKTVDDDDDDDDDDDDDRSDSHSDSDSDTPTKKEKKQNKNKKAALFARVFINTAAASGGKGKGGKGKGGKGKGQVYIDHVDELNLAKSNGASTTPNANNQAGTAATEMRRSAHQHLTVPGLVETSPRPPSAIGESRPSSQGTAGLAAAVSPTLDKMLYSHTSGALSNNNVSLVCRIDLSRLLKIPPPPPQNRPQSGLRSHDNYNAHRSASSARQKSKSPYDQLHGKRRRSSVGQQDHHDRSGSSVHSSSSTPRLLDDRVSYGGSVPNRLLAGESSPVLENGTIGSSERHRSNSINSDHSGAAQKARDYRAGLDASYGNNSPSLHHRHHPQTTYTNHHHLASQSDAGPKGVESDKYDEKLLTKSEKLGYDEQRLKEDKTTSLLYGSNRGSGGGKYSNYGGVIKQESSTPAAQSLIKQEYNRDDLLTDNKLGKPTMGLTLTNGTTGDGDTGGSGRMRKRSVSSGSNNTYKEKRRKKDKTSANLQTDQLDQLPPTNHDRLDESSSGASSGRSAIAIERNGQQHHSSTNVQGQQQQQHLTVGANGFDSGIAPVTGGDIGPPAEVPVQIKKVYVSYFERNEEVPEIRDQSRFLSEAKRLKHAADREGDHLAQAMLYLEAVLFFLLTGDTMERDPITEKAAFTMYKDTLCLIKFISSKFRSQLQNQTMQGNIHTKVAILSLRCQSLIYLKLYKMRRMDMKETGKTIGEFNHKTSTVPAELANGNTPSPLSPTSVGSQSSGYSSGQNNHVGSMPPMNSSPAQCIIMPINVHAAYQKQTTLFTHLSTCLDLWEQADSLVSRGNHVEFFIELDHENGPMTLHSSLYNVVKYVQAGIQKLRRM
The following text describes a protein:
Function:
GATA-type transcription repressor that regulates iron- acquisition genes through specific binding the GATA sequence elements of target promoters in a zinc-dependent manner. Iron acquisition regulation is critical for survival under both iron-limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity). Represses the synthesis of siderophores in high iron conditions.
Subcellular Localization:
Nucleus.
Domain:
The conserved cystein-rich region (CRR) localized between the zinc fingers is also involved in DNA-binding and transcription repressor activity; Both the N-terminal and C-terminal zinc fingers are involved in DNA-binding, although the C-terminal finger plays a more important role in the binding.
Sequence:
MALPDDTRLMNNQTSIEGNSAPDRMALPSRPPPPTASNEPPEHESTGPVDEAASKSESGLSPNSKKAGHAAQSPSGRKKSPKIQNAQPAQSPAETVGVVNVATLGLVPSVQGHAGQVCSNCGTTHTPLWRRSPQGAIICNACGLYLKARNAARPANIRRPPSVMASNVRQAAAKLSPKKATAPLLPSNPGATYVAADQTPSGSCPGGGRCNGTGGAEGCGGCPAYNNRVSKSASLNVLKCQGAAAASSKKPQAAEGSGEEPTEMDITALHVQSQNTTVVIACQNCGTTITPLWRRDEAGHTICNACGLYYKLHGVHRPVTMKKAIIKRRKRVIPAAGGDAEIEPSEAPDSPPATSEPPMEKGTVNEDGSVNLGIRRRSVRPLTLVPEDELRRNRQASPLSSAALGQYHSSHTNQPHHGAHASLTYENRLAPIHSLALPVDRQASISPASFLSPSRKRSISAVENEPSSHNDNESHKRLSSIKSILNPMPSSEIHREVSPADQLRMQPASRSPAMSSLTPAHSPGSFSNSTVIGTPTSAPILRSASRDTHNDSERMKAERRAALEREAEMMRELLAAKERELAELGYD
The following text describes a protein:
Function:
Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.
Sequence:
MNEQERLGLHHAKQTYFGNMMFTQEEHSAIQAALRQRLGREFISQRPGPGNQKLTYIEGHKAVALANEVFGYDGWSVSVLVNTIDFVDERAGRYTVGAHSIVRVMLKNGASQEDVGYGAAENVRSKTAAVEKARKEAVTDGMKRALRRFGNALGNCLSDKEYLNAAMKTTKPAKTTYNENDLKHETVDQDISNARKASLPSPTQGLPFPTPQGRPLPQAYSTPVHTAMPPPWEGNGTILSEASDSRSRQIRRNPANSRSASCGACIVPSMGAGPVTSTVANTSTGASTSSGPSSVPNTSKGLISNSDPSKDVIPTTSRGPKTNPNISAASSTNTVPKSKTSIGPQKGIGPNTSMGPNTSNGPDTSRGPGTSKGPNTSRGANTSMGSDTSIRPSTSGGSDVIPTSGHGHKKGVSPGKKRRASPRRAAQIDKTSLDDSDEAARLRKYRQWQKQQEFRQQLARRHLKQDDLPRATTSPQGADGASAGTSGNGVELEGFEEGMDDSLLANVAENEFWSEDENGADVTPTGVMTRSRTPRKHGGQGGSATLQLRQEVQGQRQPVVSRECQQGWSAQNRQPTVKKRRIDSS
The following text describes a protein:
Function:
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors and sex steroid hormones in the nucleus.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MSKEKLGDLAGRMGKAPKGLGTGMKLLAAAAALGYGVQQAMYTVDGGHRAIIFSRIGGIQDSIYTEGLHFRIPWFQYPIIYDIRSRPRIISSPTGSKDLQMVQISLRVLHRPNAMTLPRMYQHLGLDYDERLLPSIANEVLKSVVAKFNASQLITQRQQVSLLVRRELTERAKDFNVILDDVAITELSFGKEYTAAVEAKQVAQQEAQRAQFIVEKAKQERQQKVVQAEGEAQAAKMIGQAISQNPGYLKLRRIRAAQSIARTISQSQNRVYLNASSLMLNLGEEDLKASAEGLKMK
The following text describes a protein:
Function:
Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Translocates to the endoplasmic reticulum-plasma membrane (ER-PM) region in a STIM1-dependent manner following cytosolic Ca(2+) elevation.
Domain:
The cytoplasmic C-terminal region mediates interaction with STIM1, while the N-terminal lumenal region mediates regulation of SOCE activity.
Sequence:
MAVAAVGRPRALRCPLLLLLSLLLVAGPALGWNDPDRILLRDVKALTLYSDRYTTSRRLDPIPQLKCVGGTAGCEAYTPRVIQCQNKGWDGYDVQWECKTDLDIAYKFGKTVVSCEGYESSEDQYVLRGSCGLEYNLDYTELGLKKLKESGKHQGFSDYYHKLYSSDSCGFITIAVLFVLAFAVYKLFLSDGQGSPPPYSEHPPYSEHSQRFASAAGAPPPGFKSEFTGPQNTGYGASSGFGSAFGGQGYGSSGPGFWSGLGAGGLLGYLFGSNRAATPFSDSWYHPAYPPSHSGAWNSRAYSPLGGGAGSYCASSNADSRTRTASGYGGTRRR
The following text describes a protein:
Function:
Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
Subcellular Localization:
Secreted.
Sequence:
MARRRAFPAFVLRLWSILPCLLLLRADAGQPPEESLYLWIDAHQARVLIGFEEDILIVSEGKMAPFTHDFRKAQQRMPAIPVNIHSMNFTWQASGQAEYFYEFLSLRSLDKGIMADPTVNVPRLGTVPHKASVVQVGFPCLGKQDGVAAFEVNVIVMNSEGNPILRTPQNAIFFKTCQQAECPGGCRNGGFCNERRVCECPDGFYGPHCEKALCIPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSATCFNGGTCFYPGKCICPPGLEGEQCELSKCPQPCRNGGKCIGKSKCKCPKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCREGWHGRHCNKRYGASLMHAPRPAGAGLERHTPSLKKAEGRRDPPESNYIW
The following text describes a protein:
Function:
Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1.
Subcellular Localization:
Nucleus. Note=localized also in punctate nuclear bodies as well in the cytoplasm. Colocalizes with CTNNB1.
Domain:
Tne C-terminal domain is important for its transactivation activity.
Sequence:
MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIAAAHNCNVADPAMVTPQLGPGQTAQLPLSESSAPGPQHGPQPGLRPDVPGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAPKVPPTPEPLPLNTPSAGTPQSQPPPLPPPPPAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAATANNPLPPGGDPGSAPGSALLGEATPTGNGQRNLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQAPSAAQPPPSAPPGGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPQGGDMGQQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGGMMGRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRPGPPFPGPRFPGNQMQRVPGFGGMQSMPMEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDPAMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPSQFPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGTVGTARLSHMPLPPASNPPGSVHLASNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLSSSLGVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLSINSSSTLGNVEQGALPPSAPRNSSSAPPANPSSGLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHMNPAAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGSSQNSMMMAPGGPDSLNAPCGPVPSSSQMMSFPPRLQQPHGAMAPTGAGGPGLQQHYPSGMALPPEDLPTQPPGPIPPQQHLMGKGMTGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYTQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPTPGSMANLPF
The following text describes a protein:
Function:
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
Sequence:
MISVKLVSYTNDGEKVIAIAAKMSRSRKGWDYHEKDMTDDEIETWIRDAILHGYWSVLEHSVYTFSIEEISRVASHQLVRHRIASYTQMSHRFAKPIDEYYKPIIPPSAKKRSKELVEKAYKEAYDNYYTLLESGVPEEDARYVLPNGVNTNIVVTMNARELYNFFSLRLCSRAQWEIRAIAWKMLEEVKKVHPRLFKYTGPNCIIHENFIRNENESITLEDIFKDYKLEFISQRCIEGVLRDGIKKCIINSRSVLDNIK
The following text describes a protein:
Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Sequence:
MPTLEMSSMESLSHITATEALIATAVFCLLFMIVKSFRNRVPHGLKKIPGPMGYPLIGNMLELGKNPHLSLTRMSQKYGDVMMIHIGSTPVLVLSGLETIRKALVRQGAEFLGRPDLYSFRYVADGESLAFGHDSGEVWRTRRKLAQNALKSFAASPSPVSPSIYLLEEHLSKEVDYLIQKLQEVMREKKSLDPYRYIVVSVANVICAMCFGKRYSHDNQEFLSIIDESEKFVEVAASGNLADFIPLLQYLPMRSMKMFKQFNEKFTVFLLNMVKEHYESFSKDSIRDITDSLIEQSQEKFQISSKKIVNLVNDIFGAGFDTVTTTLSWSLMYLVTHPEIQKKIHEEIDEVIGRERKPRLSDRLLMPYTEAFTMEVFRHSSLLPFTIPHCTVKETSLNGYYIPKDLCVFVNQWQVNHDEKLWKDPSSFNPERFLSADGKDVNKDESEKVLTFGLGKRRCIGEQIARWEVFLFLTFLLQELEFSVKEGVEVDMTPRYGLSMKHKRCPHFLVKPRPPKNAS
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
Subcellular Localization:
Cytoplasm.
Domain:
The EIIA domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the EIIB domain.
Sequence:
MVTPTKHAIGLRSASGVELLAHIGLDTVTFDGTPFSLKVKEGDTVKKGEVLVEFDKAFIEDIEESALHQKIFTVVS
The following text describes a protein:
Function:
Phosphorylates threonine (By similarity). Not critical for regulating the assembly and disassembly of myosin II filament.
Sequence:
MEDNSFLKLSKKIEKILEKNDYLKKKVEQLTKSVDNHEFKIQELLLLLRKNNIHPTTTTTTTTTTNNNSTCVGISNSPPLSPRTSTDSMTNSNNSSATSSTTPSPTQTSTITTTSQIDPNSLTNSNNSFIPINSPISQTTVNNNNNNNNNNNNNNNNNNNNNNNNNNNNLNNQTITSPLSTSSSNSNSNSNSSSPIVSPVSSPQLSGSGNRPRIQFLGNGRMPSTGNLFKKEDSSDSLLKYSKDSEHLYIVPTTPRPSKSPSMDFIASTSLINTVSSNNTDSTNNDNSSILNDQQNQQQNQQQQNQQQQQEEINFITTEDKLPNLPDSNCQWAIIWEYSANDDEWTKALIIVEIDAKPFAKGALRNAYQLKIRSNAMQCFNHFATPIHEKYMEGKKLNLSQIPKLNQNLSLDTLYVAKDSKTSVNFNRYFEDVKMQMVCKSYGERYNSNHPPKKIEFLSAWVIEIQGTTNYRVGNRNSSNNTLYGLELFMKGEFKKQNSNFGTVFTERNTPQSFSHFTYECTTHEMVVVDIQGVDDIYTDPQVHTKDGKGYGEGNLGQKGIEKFLISHKCSPICLQFGLPPIGLETGRNAHRVIRGTMLLPDLTPDLYEPEYPLIENQPSNPLNSELTSIVHLSGHDERVCSLLINQDKTKLYSASADGYVKIWNLTNNEDLSKIQMIDSFRAHRRSIEKMLLNEKYLFTASSDGTIKIWSLPTTTTTTTTSKQSSSSSSSSYECIGKLEDHTAEVNDMCIDIENNFLVSCSFDKQIKIYDLSTFKCIKSLNAHGKSIKSIYMSGKYLFSSSNDQSIKIWDLEMCMCVYGMNDAHDAPITSLRMFGNRLFSASKDGEIKDWNLSTFQPTTTLDQHNMAITDILVTSNGYLFVSSDDSTIRIIDISNQNEPIKIISSTKAHRSGVNSLATDGKRIFSGGCDNLIKVWNWKNK
The following text describes a protein:
Function:
Has broad nucleoside selectivity (uridine, adenosine and cytidine) and most likely functions to transport nucleosides across intracellular membranes.
Miscellaneous:
MISCELLANEOUS: Present with 217 molecules/cell in log phase SD medium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSTSADTDTIKKPILAVPEPALADTHSEEISRSGEEHESENNEHSDEEGDNYSEREQSVSTEPLDTLPLRKKLKNLSYITFFAIGIGLLWPWNCILSASQYFKHDIFKDTSIWAKIFTSSMMSFSTISSMLFNIYLAKRQYKYSRRVINGLVWEIIVFTVMCFFTILHFLLPKWFNFMFIMMLVVISSMGTAMTQNGIMAIANVFGSEYSQGVMVGQAVAGVLPSLVLFALAFIENSSVSTTGGILLYFFTTTLVVTICVVMFSVSKISRKVNENWNVEDGHITDVLLGSLRSNEEEIRIVGRIDQMEDEDHRRTNGTRDDNDEGEELQLKVPFEVLFAKLKYLVLSIFTTFVVTLVFPVFASATYVTGLPLSNAQYIPLIFTLWNLGDLYGRVIADWPMFRDQKFTPRKTFIYSLLRVAAIPLFLMFTAITSSSSGDEEHNGSVIVDLCYMLLQFLFGVTNGHVISMSFMKVPEQLDNDDEKEAAGGFTNIFVSTGLALGSIISYVFVFIIDFIIR
The following text describes a protein:
Function:
Metalloendoprotease which is required in the dorsal paired medial neurons for the proper formation of long-term (LTM) and middle-term memories (MTM). Also required in the mushroom body neurons where it functions redundantly with neprilysins Nep2 and Nep4 in normal LTM formation.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MTRYKQTEFTEDDSSSIGGIQLNEATGHTGMQIRYHTARATWNWRSRNKTEKWLLITTFVMAITIFTLLIVLFTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW
The following text describes a protein:
Function:
Phosphatase active on para-nitrophenylphosphate (pNPP) and on various phosphoproteins such as myelin basic protein. Seems to act as a positive regulator of cryptochrome signaling involved in hypocotyl growth inhibition and cotyledon expansion under white and blue light conditions. Confers thermotolerance. Required for heat shock mediated-signaling pathway that leads to the expression of heat shock proteins (HSPs).
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to an intron retention.
Subcellular Localization:
Nucleus, nucleoplasm.
Sequence:
METVPPSPITWPDGGALTNDWVHGLMSCFEWSSWNLPPSQLPSLLPVNVFDSLVLTAHKILHKERNCVHIDDLDSVSNVVVVGDIHGQLHDLLFLLKDTGFPCQNRCYVFNGDYVDRGAWGLETFLVLLSWKVLMPDRVYLLRGNHESKYCTSMYGFEKEVLTKYGDKGKHVYRKCLGCFEGLPLASIISGRVYTAHGGLFRSPVLPKRTTRGKKNRRVVLLEPEPSSMKLGTLDELMQARRSVLDPPWEGSNLIPGDVLWSDPSMTPGLSPNEQRGIGLLWGPDCTEDFLKKYELKLIIRSHEGPDAREKRTGLGGMDNGYTIDHNVESGKLITIFSAPDYPQFQATEERYKNKGAYIILQAPDFSDPQFHSFEAVKPRPKAHPYYDFENVIDSDDEMDKSAMDTNNEQPNS
The following text describes a protein:
Function:
Calmodulin-binding protein that functions as a negative regulator of osmotic stress tolerance.
Subcellular Localization:
Nucleus.
Sequence:
MVTSEGLASVDSWLYRQGFNVDSWLLSDTFSHDNDLLARALHTTVTAPHTLTPSSAFFDSSAVSHPSSTNTLSSTVSGASDPEIIGGGAKRKRNCLLTDGKAAKRRARASKKSQTTFITADPSNFRQMVQQVTGAKYIDDSSSFGIFDPIVKPEPLRFVNKLPCGPSDRSTAVPMLDTSAFLSNHHQENLAVGNAFSGNSSSVGLPSGKPSATADPGGSAVEFDNYPTFPTLESWKVM
The following text describes a protein:
Function:
Short-chain dehydrogenase/reductase involved in the biosynthesis of abscisic acid (ABA), a phytohormone that acts antagonistically toward salicylic acid (SA), jasmonic acid (JA) and ethylene (ETH) signaling, to impede plant defense responses. During pathogen-host interaction, ABA plays a dual role in disease severity by increasing plant susceptibility and accelerating pathogenesis in the fungus itself. The first step of the pathway catalyzes the reaction from farnesyl diphosphate to alpha-ionylideneethane performed by the alpha-ionylideneethane synthase ABA3 via a three-step reaction mechanism involving 2 neutral intermediates, beta-farnesene and allofarnesene (By similarity). The cytochrome P450 monooxygenase ABA1 might then be involved in the conversion of alpha-ionylideneethane to alpha-ionylideneacetic acid (By similarity). Alpha-ionylideneacetic acid is further converted to abscisic acid in 2 steps involving the cytochrome P450 monooxygenase ABA2 and the short-chain dehydrogenase/reductase ABA4, via the intermediates 1'-deoxy-ABA or 1',4'-trans-diol-ABA, depending on the order of action of these 2 enzymes (By similarity). ABA2 is responsible for the hydroxylation of carbon atom C-1' and ABA4 might be involved in the oxidation of the C-4' carbon atom (By similarity).
Sequence:
MGSIENPEIMASTMLHILPLAGKVYGITGGASGIGLATAQILSRRGATVCIADVDPKAMASAEVYFSGQSGAKYSITKVDISKRSEVNAWVDGIISQFGRLDGAANVAGVIGKIHGAVPVSEMDDDEWDKIVAVNLTGTMYCMRAQLRNIVDGGSIVNVASIHGLKGFANHAAYDASKHGVIGLTKAAAQENGAREIRVNAVAPGAIYTPLMQKNWDITGRPKDAPFDDPSAFRRQGTAMETGNVIAFLLGPDSTFVSGSVYSVDGAWI
The following text describes a protein:
Function:
Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.
Sequence:
ALSPLCESQIYCHGELLHQVQMAQLYQDDKQFVDMSLATSPDEVLQKFSELAVAHNHSIPREELQNFVQSYFQPVGQELQPWTPEDWKDSPQFLQKISDSRLRVWAEELHKIWKKLGKKMKAEVLSHPERSSLIYSEHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVKTYGHIPNGGRVYYLQRSHPPLLTLMMERYVAHTNDVAFLRENIGTLALELEFWTVNRTVSVGSGGQSYILNRYYVPYGGPRPESYSKDEELAKTVPEGDRETLWAELKAGAESGWDFSSRWLVGGPDPDLLSSIRTSKMVPADLNAFLCQAEELMSNFYSRLGNDTEAKRYRNLRAQRLAAMEAILWDEQKGAWFDYDLEKGKKNLEFYPSNLTPLWAGCFSDPNVADRALKYLEDNKILTYQYGIPTSLRNTGQQWDFPNAWAPLQDLVIRGLAKSASPRTQEVAFQLAQNRIKTNFKVYSQKSAMYEKYDISNGGHPGGGGEYEVQEGFGWTNGLALMLLDRYGDQLTSGTQLASLGPHCLVTALLLSLLLQ
The following text describes a protein:
Function:
Functions as a two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Domain:
Histidine-containing phosphotransfer domain (HPt) contains an active histidine that mediates the phosphotransfer.
Sequence:
MALHIHKGLLQGFIQCMYDEGFVNDQFWQLQMMKSSRNQPDYVVRVVTSYCSSAQTLFSQLTHHINQENVDFLQVKVSARELYDKSSSVGAEHVKLACAELLVACEGHDKEYCSKALYWTKNEFAHLRRKFETLVQCRWRGRSLILKVHLEGN
The following text describes a protein:
Function:
Terminal nucleotidyltransferase that catalyzes preferentially the transfer of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation. Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation.
Sequence:
MDPRVAWIQPEQKGPANALWMQIWETSQGVGRGGSGFASYFCLNSPALDTAAAPGAAGRAAPAAGGPGPAPAASSPPPAPGPAALPPALLTALGPAADGARRLHKSPSLSSSSSSSSNAESGTESPGCSSSSSSSTSLGRAGSGRTFFSFADGAAHAHPGPRGPTPAGSPPQHQFHPGRRKRENKASTYGLNYLLSGSRAATLSGGGGPGAQAARPGTPWKSRAYSPGIQGLHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPSADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDSESTLGRIIKVTQEVIDYRRWIKEKWGSRIVPSPDLDNRIKIKERVTTCNGEQMQSREPSSPYSQRLTLSLSSPQLLSSGSSASSVSSLSGSDIDSDTPPCTTPSVYQFSLQAPTTLMAGLPTALPVPSSKPQPAASRTLIMTTNNQTRVTIPPPTLGVAPVPCRQAGVDGTTSLKAVHNVTSPAIPSASPNPLSSPHLYHKQHNGMKLSMKGSHNHTQGGGYSSVGSGAVRPPVGNRGHHQYNRTGWRRKKHAHTRDSLPVSLSR
The following text describes a protein:
Function:
Irreversibly catalyzes the reduction of fumarate to succinate.
Sequence:
MSKILSSIPGNMSKSIAKYDTIVIGSGLAGLTTTYQLSKAGQKVALLEKSEKLGGNSIKASSGINGVPTKYQKQPSTDSIESFVQDTLKTGKNLNDKKMVDILTKNSRDAIYWLSDEINVDLSNVVLLGGHSHARTHKGDKLPPGFAIVSALTKKLDGFQAENPDQLTILKSSTLTKILTEGNKVKGIEFTDSEKQPQEMYADNVVLATGGFSADFDSPTSLLQKYRPDLLGFPSSNGAQTTGDGQKIAERDVNAELIHMDKVQVHPTGFMKVSNPNENWKFLCGELMRGIGGILLSPVTGWRFVDELQPRDVVTDAVLKHSQIGQNNEIGLKSDNGDGYGSVIVISGNDYQKATTHIEFYKSQGLLQEGSIEDLYYLLIKLNPKLPLTLDQLKDKFSGCDAIIEGTQQDSLGRTKFGGRFGDLKKLYFGVTTPVVHFTMGGIKVNPSNAKVVTKSGDTISNLFAIGEVSAGVHGNNRLGGSSLLECVVFGRFVSENILSGKN