lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. Involved in the export of mRNA from the nucleus to the cytoplasm. May play a role in mitotic spindle formation and/or function.
Subcellular Localization:
Cytoplasm.
Sequence:
MPPKKAAKGKGDPGKAAKKDPTKKAADATFGLKNKNRSTKVQAKIRQIEQNAAASGSKDAKRQEALRKRREEEKRAAEAAKAEVAALFNAIPKKQTPQNFLTRKEEVKESQKIDLYSDVRDQQTDLPLEKRPWINTDIVCKFFLEACETGKYGWLWQCPNGNMTCIYKHALPYGYVLSRDKKKDDTKEEISLEAFIEIERHRLGPNLTPVTEENFKKWSDGRRDRILKQAEERRSNRAVGRSNLSGREYFESNKDKTHEVVGDEEDWDFSALRRETEALAKAQDATAPIVSV
The following text describes a protein:
Function:
Functions as a guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion.
Sequence:
MGEIEGTYRVLQTAGTRLGAQTPVGVSTLEPGQTLLPRMQEKHLHLRVKLLDNTMEIFDIEPKCDGQVLLTQVWKRLNLVECDYFGLEFQNTQSYWIWLEPMKPIVRQIRRPKNVVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCADTTAALLTSHLLQSEIGDYDETLDREHLKANEYLPGQQHCLEKILEFHQKHVGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKIQLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLLDQPKPKAKAVFFSRGSSFRYSGRTQKQLVDYFKDSGMKRIPYERRHSKTHMSVRALTADLPKQSISFPEGLRTPASPSSANAFYSLSPSTLAPSGLPEFKDSSSSLTDPQVSYIKSPAAERSSGAVAGGPNTPSAQPLGPPALQPGPGLSTKSPQPSPSSRKSPLSLSPAFQVPLGPAEQGSSPLLSPVLSDAGGAGMDYEEPRHKRVPADEAYFIVKEILATERTYLKDLEVITVWFRSAVVKEDAMPATLMTLLFSNIDPIYEFHRGFLREVEQRLALWEGPSKAHTKGSHQRIGDILLRNMRQLKEFTSYFQRHDEVLTELEKATKRCKKLEAVYKEFELQKVCYLPLNTFLLKPIQRLLHYRLLLRRLCGHYTPGHHDYADCHDALKAITEVTTTLQHILIRLENLQKLTELQRDLVGVENLIAPGREFIREGCLHKLTKKGLQQRMFFLFSDMLLYTSKGVAGTSHFQIRGLLPLRGMLVEESDNEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMLDLNSAIQAAKSGGDTTPALPGGTVCTHPPRCPNEVPLEQESEDDARGVRSSLEGHGQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSHGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSIPREADGIHKDYVFKLQFKSHVYFFRAESKYTFERWMEVIQGASSSAGRAPSIVQDDPQPSSGLEGMVRGKEE
The following text describes a protein:
Function:
Probable transcription regulator that binds to cis-responsive elements of genes involved in stress response.
Subcellular Localization:
Nucleus.
Sequence:
MEPSDDACTVAAPAAETAASSSGAGGGGGGGRTKKKAAGKGGPENGKFRYRGVRQRSWGKWVAEIREPRKRSRKWLGTFATAEDAARAYDRAALLLYGPRAHLNLTAPPPLPPPPPSSAAAAAASSSSAASSTSAPPLRPLLPRPPHLHPAFHHQPFHHHLLQPQPPPPPPPLYYAATASTSTVTTTTTAPPPQLAAAAPAAVLVAAAVSSTAETQAVVATAPEDAASAAAAAAAEEEAAWGFHGGDEEDYAAALLWSEPDPWFDLFLK
The following text describes a protein:
Function:
Catalyzes the iterative condensations of 5 molecules of malonyl-CoA to produce a pentaketide 5,7-dihydroxy-2-methylchromone.
Miscellaneous:
MISCELLANEOUS: A.arborescens is a medicinal plant rich in aromatic polyketides, such as pharmaceutically important aloenin (hexaketide), aloesin (heptaketide) and barbaloin (octaketide).
Sequence:
MSSLSNSLPLMEDVQGIRKAQKADGTATVMAIGTAHPPHIFPQDTYADVYFRATNSEHKVELKKKFDHICKKTMIGKRYFNYDEEFLKKYPNITSYDEPSLNDRQDICVPGVPALGTEAAVKAIEEWGRPKSEITHLVFCTSCGVDMPSADFQCAKLLGLHANVNKYCIYMQGCYAGGTVMRYAKDLAENNRGARVLVVCAELTIMMLRAPNETHLDNAIGISLFGDGAAALIIGSDPIIGVEKPMFEIVCTKQTVIPNTEDVIHLHLRETGMMFYLSKGSPMTISNNVEACLIDVFKSVGITPPEDWNSLFWIPHPGGRAILDQVEAKLKLRPEKFRAARTVLWDYGNMVSASVGYILDEMRRKSAAKGLETYGEGLEWGVLLGFGPGITVETILLHSLPLM
The following text describes a protein:
Function:
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSEARTVLFRLSNLGEPVNNENIANGVLILPVVELPSNYKPGDALFQLRFQLNAASKVSRNGTLYTNVPSKYEQDFDRNTHYQYPIKSSFHEDITITVPIYKPGSYNYYIEYDDEEDNKKTTEKYYFNVPPNLTINGKFVPFNNINVETVVSKWIGPYENWDKFFKIVAQKGYNMIHFTPLQERGESDSPYSIYDQLKFDPKIFPGSDKDAIQKIHKVLNDNQLLSLTDVVWNHTANNSEWLREHPDSGYNATTAPHLIPAIELDEALLEFSHSLQELGLPTVLESEADLQKVMDGIQTHVLDKLKLWEYYVFNKRQTIVDLEKSFNDNKNNINKIQIPNDVDSQDLKQLSDYVLKVANINPTPIIGDRFANKLNVDKFLGVLFTVFDNNVEFETIANRAEEIIDEINSDLYAAFDDDTNSIKQQVADRIKYLRLADNGPKLGEITDKSPLTEPYFTRFTDVNGKKQALANNGWIWGGNPLVDFASNKSKAYIRREVIVWGDCVKLRYGEKFEDSPETWKRMIEYTQLSAKTFNGFRIDNCHSTPLHVGERLLDEARKVNPNLYVIAELFSGSEEMDKIFVERLGINSLIREAMQAWSVGELSRLVHKHGGRPIGSLTWLPLDDFTYPAANEPVKDKFIDGYTELEIPKVLTCQAPHAIFMDCTHDNEMPAQKRTVEDTLPNAALVAFCSSAIGSVFGYDECYPKLLNVVSETRHYDLDSDNGIGKVKAKLNKIRDDLVQESEDVTRDHEMYIHHEGQYITIQRYNARTGNGWFLIARSKFSDHESAQGLSPSILGGTKVKHQFSYSLIRQPGDYESQQDKLTGIPVQVEAIQSPSIEYTDDGDSIITIDEASFIPGSIAVFSTEIPGVDVKLDNFVKQGAIEASIGLDLYDLNALLYRASTEELDASNGKDDVYDIPGYGRLTYAGLEGWNTALKHVIWQNNLGHAICDHLRNGDWAFDYVVNRLDKYAAKSENLSKFQDWLRSRFDAVKKSKAPYFLRPHYFALIMGIAYEAARFRVIRQMSDGIKVATNFVQSLALTSVQMVGYMQNTSLVPDKQVPCMAAGLPHFSNDYMRCWGRDVFIAFRGLLIVTGRYDDAKQHILGFAKTLKHGLIPNLLDAGRNPRYNARDAAWFFLQAIQEYVTYAPNGIDILDEKVTRRFPLDDTYIPVDDPQAFSYESSIREIIYEILSRHAKGIKYREANAGPNLDSQMRDEGFNVEVGVDWTNGLIYGGNQFNCGTWMDKMGESEKAHNKGIPGTPRDGSAIEIQGLLKSALRFVNKLHKQGKFEYTKVTKPDGSTISLEDWESLLAENFEKHYYVPKDPQQDDQYVIDPSIVNRRGIYKDLYNSGKPFEDYQLRPNFAIAMCVAPELFTPEKALGAIIIADKAIRGPIGMRTLDPSDWNYRPYYENSIDNDDFATSKGRNYHQGPEWVWNTGYFLRAFLLFHHLEEESSKASSSSPSIKILTLLNDRLQGHIKWIKESPWNGLTELTNKDGSYCQDSSPTQAWSGSCLLDLYYDLWNDKHFQ
The following text describes a protein:
Function:
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
Subcellular Localization:
Cytoplasm.
Sequence:
MNKTILIEWDKKYIWHPFTQMKNWLDDEPTIFIEGRDCFLKDIDGKWYLDGVSSLWVNIHGHRRQEIDEALKSQIDKLAHSTLLGACNEPSIVLAKKIADLLTENGVPLTKIFYSDNGSTAVEIAMKIAYQYWINQGIKGKDTFVSLKEAYHGDTIGAVSVGGVELFHEVYKPLLNKSIQAPAPYCYRCELNHTYPACELGCLNEMEKIIAQNQEKVIAVIVEPLVQCAGGIIVWPEGYLKGLRELCNKYNILLIADEVATGFGRTGKMFACEHEKVSPDIICLSKGITNGYMPLAITAVNEKIFNAFIGELEEKKTFYHGHSYTGNPLACAAALANLEIFEKEKTVEKLLPKIELLKNKLLEIAQLPYVGDVRQKGMIAGVEIVKDKKNKESFPYFEQTGWKIVKSARKYGVWLRPLGDVIVIMPPLVISEENLERLLEVIKGCIIGLNY
The following text describes a protein:
Function:
Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKNKPLAFQIWVVISGILLAISILLLVLFSNTLRDFFTNETYTTIENEQHVLTEYRLPGSIERRYYSEEATAPTTVRSVQHVLLPENEEASSDKDLSILSSSFIHKVYKLADKQEAKKKRYSADVNGEKVFFVIKKGLSVNGQSAMMLSYALDSYRDDLAYTLFKQLLFIIAVVILLSWIPAIWLAKYLSRPLVSFEKHVKRISEQDWDDPVKVDRKDEIGKLGHTIEEMRQKLVQKDETERTLLQNISHDLKTPVMVIRGYTQSIKDGIFPKGDLENTVDVIECEALKLEKKIKDLLYLTKLDYLAKQKVQHDMFSIVEVTEEVIERLKWARKELSWEIDVEEDILMPGDPEQWNKLLENILENQIRYAETKIEISMKQDDRNIVITIKNDGPHIEDEMLSSLYEPFNKGKKGEFGIGLSIVKRILTLHKASISIENDKTGVTYRIAVPK
The following text describes a protein:
Function:
Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
Subcellular Localization:
Secreted. Bacterial flagellum.
Sequence:
MARLQSSIGLVTGTDIVGTVDQLMAINAQPRDRILAKTEELLGQQQQIASLTASVIGVQLAGDALGSSALFSSKNATSSNEDALSVSTRDEVTNGNHLVRTLRTAATHSVSSAQSFSTFDEALSLAGSLTIKPSGFVDSKVSLSQLNNGLGVEGGSIRLTDRSGASAEVDLSQARTVDDVLQAINDADVGIQATTSGGKIKLIDQTGQSISNLKVEQLGTAETAADLGLHGIDVASSSVDGNDIPLPDGVDSLNGASLSQLGGGNGLGTLTSLDIQTGDGTSASIDVSGATSLNEVIDAINGSGLDVIARINDAGNGLRIRDVSGGPGTFEISSADDTATSLGIAASTTDDIVVGEDLNFQSVTLETKLSELNSGDGVGTGSFTIRDSNGAVGGINLAVSEIETIGDLIDAVNALDIGVEAALNEAGDGVVITDTAGGASSLKITDTGEGKVAASLGLAGTADAGTSLVGSESVTIEITEDDTLESIVEKINESDRYADASVVSNSDGSYSLQIRSKKGGEVGRISVNLDGVDLNLRTNSKGQDALISIATDGGTERFLTSTDGVFEDEISGLNLTVKELSEDPITVNVDDDPDAIVSAVKRFADQYNKLIDKIQEVTFFDAEANEVGLLFGSTETLRIQNGYSRLLTGTVPLSSGDSIRSFSQIGVRMDENGELQVDETKLKAALANDTEAVEQFFNKTNDEDENIGMVGQLKKLADTYAGVDGGMLIRKTQTLSAHIERNDARVESMNDLLESQRERLLKQYYDMEQAIAKLQANTSSIGAIEYIGPVGSE
The following text describes a protein:
Function:
Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MNKSLVPSSSSLLNVNRILVRNVATKQLAPSLSVLSTRILKNHFTTKFKQHSIAFNKQRYFSTFSRSYQEPLNKHTQPKDELKQTITKATLLSQANSGLSRMLIHLKWPLSRNTNTTSTWDMTSAFISWLVMGNILWIILGTTTFGLTLMYSLHYLDSLVGKFSDDKETTDKLNQTKSKTSTNVMSYLIGGIISFGIGVDLNFEKGSSLPELKDGKLRFKNVGIVSHDGNNKHVKFKGTVEAMDITLSFNKWYEGNGLIYDLELYGLNGKLYKSRSPSPPVANTTKKSYRFNENIHYQYDLDHNVEEIASGSSSIIDNNYTFDHVKIHDSYLEIYEEQSSTPIKINIFSCDLPKLRGDKLVLDFFNANNASGAINDAMFTLHKRQNLDPENKNQDKLIRFKLDAIDLGEINKYDPNSKFNWIINGKAEVIADITLPEEQDDLNESITEVLTKMFTNMFQTADMSQTSEDSLLKDAISAIYHTFRKPEETAKPAENSYVMVNVKMKLYDLKASLPQVLPRTNNGIPFISLTDLRSLISFINTENQPITIKSTVIEKITDLSNIQHLGQTKMFDYIMGDAYEELTNLVRDDARRIINEKSWSNSIATQLLLLGLGAMV
The following text describes a protein:
Function:
Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
Subcellular Localization:
Cytoplasm.
Sequence:
MSRTPSEVIAYAKANNVLFYDFRFTDIKGAWHHVSYHAGSINEDSFKGLPFDGSSIPAWQPIDRSDMQLIPDTSAIFLDPFTADSTLVVFCDVFDIYKGTLYEKCPRSIAKKALKYLESSGLADTAYFGPENEFFIFDNIKVRDAINVQYYEIDSSEGIWNSHTDFPGSTNTGHRPGTKGGYFPVAPVDSQVDLRADIVKTLHQIGMETFVVHHEVAQGQGEIGVKFGTLIEAADNVQKLKYVVKMVAHKYGKTATFMPKPLYGDNGNGMHCHQSIWKNGVNLFAGKGYQNLSDTAMHYIGGVLSHAKSCAAFTNASTNSYKRLLPGFEAPSILAYSAQNRSASCRIPFVNGDKARRVEFRFPDSSANPYLAFAAMLMAGIDGVQKKIDPGPPREEDLFELSLDEIREKGIQQMPHTLRESVEHMLLDKEFLKKGDVFTEEFIQTYKAYKFETEIWPWEGRPHPFEFLTTYSC
The following text describes a protein:
Function:
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
Subcellular Localization:
Cytoplasm.
Domain:
Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
Sequence:
MSHPNVLLLGAPGAGKGTQSRRLVDEFGVEHVTTGDALRANKTKDITHLDVEYDTPGAYMDAGELVPDAVVNEIVKTALDDADGYVLDGYPRNESQTEYLDSITDLDVVLYLDVDEDELVGRLTGRRVCEDCGATFHVSFNQPETEGVCDACGGSLYQREDDTEETARERITVYEENTAPVVEYFREQGVLAEVDGERTPDEVWTDVAAAVDERTA
The following text describes a protein:
Function:
Plays a role in mitochondrial morphogenesis.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MSELDMHSNNGQANGRASNSSNNSNNNSSNNRSQKCYVIKEVYENGSALENFESQLDCAIYSNIETIIIEPTKLGKETSSWISLGNWIKFSSLASGVTCLSVGLVIPDRPIFYAPLGVFSFISGAVYAVSWQLDPCSRYKVERDQSKLQCLPVSNLRSSSPIVIVRKSGIPSFLYAVVSVSALSYSIWRIIK
The following text describes a protein:
Function:
May play a role in embryogenesis.
Sequence:
MSTVNHHCLLNFPHIPPSIPPNHRPKLLSSLSLYRKPERLFALSASLSLSPATIHECSSSSSSSSSSFDKEETEDIESVIDGFFYLLRLSAQYHDVEVTKAVHASFLKLREEKTRLGNALISTYLKLGFPREAILVFVSLSSPTVVSYTALISGFSRLNLEIEALKVFFRMRKAGLVQPNEYTFVAILTACVRVSRFSLGIQIHGLIVKSGFLNSVFVSNSLMSLYDKDSGSSCDDVLKLFDEIPQRDVASWNTVVSSLVKEGKSHKAFDLFYEMNRVEGFGVDSFTLSTLLSSCTDSSVLLRGRELHGRAIRIGLMQELSVNNALIGFYSKFWDMKKVESLYEMMMAQDAVTFTEMITAYMSFGMVDSAVEIFANVTEKNTITYNALMAGFCRNGHGLKALKLFTDMLQRGVELTDFSLTSAVDACGLVSEKKVSEQIHGFCIKFGTAFNPCIQTALLDMCTRCERMADAEEMFDQWPSNLDSSKATTSIIGGYARNGLPDKAVSLFHRTLCEQKLFLDEVSLTLILAVCGTLGFREMGYQIHCYALKAGYFSDISLGNSLISMYAKCCDSDDAIKIFNTMREHDVISWNSLISCYILQRNGDEALALWSRMNEKEIKPDIITLTLVISAFRYTESNKLSSCRDLFLSMKTIYDIEPTTEHYTAFVRVLGHWGLLEEAEDTINSMPVQPEVSVLRALLDSCRIHSNTSVAKRVAKLILSTKPETPSEYILKSNIYSASGFWHRSEMIREEMRERGYRKHPAKSWIIHENKIHSFHARDTSHPQEKDIYRGLEILIMECLKVGYEPNTEYVLQEVDEFMKKSFLFHHSAKLAVTYGILSSNTRGKPVRVMKNVMLCGDCHEFFKYISVVVKREIVLRDSSGFHHFVNGKCSCRDLW
The following text describes a protein:
Function:
Catalyzes the second (last) step of the biosynthesis of Kdo8N (8-amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno-octulosonate).
Miscellaneous:
MISCELLANEOUS: Kdo8N is found in lipopolysaccharides of members of the Shewanella genus.
Sequence:
MPGFELFGPEEKQEVADVMEHGFTFRYNFDHMRNDRWKTRDMEQLLCEKMNVKHAHLLSSGTAALQTAMMAAGIGAGDEVIVPPFTFVASVEAIFMAGAVPIFAEIDETLCLSPEGIEAVITPRTKAINLVHMCGSMAKMDEIKAICKKHNLVLLEDACQAIGGSYKGQALGTIGDVGCYSFDSVKTITCGEGGAVITNNTEIYDNAHMFSDHGHDHIGKDRGAESHPIMGLNFRISEMNAALGLAQLRKLDTIIDIQRKNKKAIKDAMASIPEVSFREIPDPEGDSAGFLSFMLPTEARTQEISKKLAANGVDGCFYWYVNNWHYLKNWKHIQELKAPAALPITLIADRPDYTQISVPKSDAIMSRTISMLIKLSWTDAQIAERIENIKKAFAQ
The following text describes a protein:
Function:
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
Subcellular Localization:
Mitochondrion.
Sequence:
MRAYAASSRGPLQRRLLHTSRSLTYNVLAIETSCDDTCAAIISRDREKNTAALIDHVKITLDSSLQGGINPALATAHHHQSVGPLIRDVLKKHADTTIDLVCATRGPGLPGCLSSGVTFAKGLSLGLGVPYLGVHHMLAHLLTPRLFEAAEGYSGHKTEFPFLSLLVSGGHTMLVLSKSLYDHTVLCNTADVAIGDALDKCARTLGFQGNMLGKVMDQYCRSADTPSSQWSIPMPVDNKNDIRYSFAAFHSYIGMKKKETQAETTPELALEVQTAIFNHLMKKTKAAFNIYKKEIASATTLVCSGGVAANPRLREALQELCAKYKLEAVFPDPYWCTDNAAMIGWAGIELHEDGYRSDLEGFQIPKWPLAEFEKEI
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
Subcellular Localization:
Nucleus.
Sequence:
MQRRWRRVAEFGRWLENEVKGVHVGVNLYLTPEALEDEEGGGKQDRQGFEAHWDWMDAFDAPFFTDQWKSLVVIVIQLSGRKRWRVAKQPTIFLSNKDQKRRPTNEEAQYFATDEGHYVEFTMCPGDSLYIPRGFMHNASTVDFDELQSTDDKGEKIGGEWDDCPANPSDLNTTQRLLLANHQLSGPSLHLTFGIEQGCAGTMESLLHHAIHAYFAEGVSKDSEYQQLIVPASEGATWKSILHHSLAEVARRRHDECDNPRAENTRMCDGSALLRRSVPLLLLNNTGINAMNGEEKNQYATLKLSYLKALDTFESTSNLAQTLSFVQTHREQSTDDADLSFCFPGYTLQENKLVDVLSQSEAMTTNHAKMVEGFVRYANADDSFEEAMQRMNKHGMILREKDWTRQDHDLEVVGQ
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. Has RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides (By similarity). Overexpression in M.tuberculosis or M.smegmatis inhibits colony formation in a bacteriostatic rather than bacteriocidal fashion. Its toxic effect is neutralized by coexpression with antitoxin RelJ (shown only for M.smegmatis). Overexpression also increases the number of rifampcin-tolerant persister cells; In combination with RelJ represses its own promoter. Several DNA-protein complexes are formed in vitro depending on the RelJ:RelK ratio.
Sequence:
MRSVNFDPDAWEDFLFWLAADRKTARRITRLIGEIQRDPFSGIGKPEPLQGELSGYWSRRIDDEHRLVYRAGDDEVTMLKARYHY
The following text describes a protein:
Function:
Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).
Sequence:
MALQNIGAANSDDAFYRYKMPKMITKIEGRGNGIKTNIVNMVDIAKALARPASYTTKYFGCELGAQSKFDEKTGTSHVNGSHDTAKLAGLLENFIKKYVQCYGCGNPETEVIITKSQMIQLKCAACGFVSDVDMRDKLTTFIVKNPPETKKGSKDKKAMRRAEKERLKEGEAADEEQKKLKNGKKKGSSTKDGHAKASSIKKKANSSDEERGSPTHSQVDEKEEADDEDDVQWQTDTSLEAARQRIQEQLSAATADMVMLAADETEKNSKTASKENGSPREEEPKAGCGNSSAYETLVEEVKANLKKGVSASKIQSVLGSLDGSAQEKMNGLFEALFEGVEKGFAKEVGKKKKYLAAAVAQDEGSQLLLLRAIGAFCGKSSSSALKEVALVMKDLYDADVLEEEYIVQWYQEGLEGPSKDSQIWKNAKPFIEWLQNAESESEEE
The following text describes a protein:
Function:
Catalytic component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Has a role in regulating heterochromatin propagation and euchromatic transcription. Also has a gene activating role.
Subcellular Localization:
Nucleus.
Sequence:
MYNPESFNNDKMLRLPSQDNSDQALWAIFGRNEDLTPQTNGVVRAQANSLDLSQEEQTGHADTSTATDNLNKNADNYLQPGPSFLIASQLSSQTNKTTNSMTRYGARYVSAEAPISVKASVPSLPRVTYDRLCKEAALSCGLPSDALHPYEAKMLGEILETSSWLTKYVDIRNGLCYLWIRNPTLFISFTEALGIVREKDTFPLASLAFEFLTRNGYVNYGCLYIPFTVPYNETLPQKSVAVVGCGLAGLSCARQLANLFAQYEQDFVNRNENVPRLVVFEADSRIGGRILSHRLESSQTNADVEKTSSTDEEPTQHFIEIGADRILEMNNAMDPLRIVADQQLSLDVQIHETPLVKLISEDGSSVDPATIQRICELFDCVVFAVTLSNDKITLNGVLTPEEQSLRERLDFLQRFGYHLSLEHFRFSNEGSLGSTLKRALSILNDFIQFNDVELQVLNWCLNYLQQGVGANLDFVSTKCWSCHYQPICQLSNSMTIGEGMSSIVQHMASTPTPLPIQLNHSVVSVKYNDTGVQLISSNQQVINVDKVVLCLPLSVYKKHTLTFEPALPDWKVTSLNRVSTSNFRKVNLLFSHAFWDSEATVFGKVLGNSFNDIPMQSLIFFNYFKQTGLPLLITNYFASENESDSEISEKVMNALTDQFSHMQNFVRPKSVFISNWNTLPFSSGSLSVATSSFSAADYKALAAPLENTVFFASDSMSGESLGTLHSSFRSGLMAARDVLASLVGDVAIPQTLIVNQASKQTNTTTQSSNTSSTRRNTRSREQVTPKFSYRSEYIKAKQARLEKENQECQMLIQELLGAPPEMPSRPTANPFLLYQKTQWHVCKAMADKDRQEATGDPEARATKNEIRAKLGRSWRDLDESGKQPWIDEVNARRANYTALMEEYQRQLNTFNTRAAQIKAEHRRKCEAQPIPVEESRLQALAENEEEERARNEPPSTNSHMSNVYDESDDEYHDEGEDEDDDVADDLYSNGYL
The following text describes a protein:
Function:
Inhibits programmed -1 ribosomal frameshifting (-1PRF) of a variety of mRNAs from viruses and cellular genes. Interacts with the -1PRF signal of target mRNA and translating ribosomes and causes premature translation termination at the frameshifting site. May exhibit antiviral activity.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, P-body. Note=Predominantly found in t for dsDNA.
Sequence:
MAQDGVELEKSVRRLREKFHGKVSPKKAGALMRKFGSDHTGVGRSIVYGVKQKDGQELSNDLDAQDPPEDMKQDQDIQAVATSLLPLTQANLRMFQRAQDDLIPAVDRQFACSSCDHVWWRRVPQRKEVSRCRKCRKRYEPVPNDKMWGLAEFHCPKCRHNFR
The following text describes a protein:
Function:
Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.
Subcellular Localization:
Cytoplasm.
Sequence:
MLAFQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFRKGKRYFYFYNTGLQNQRVLYVQDSLESEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQDGKSDVLTPAGTETSTNLHQKLCYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESNGITGILTWVKLIDNFEGEYDYVTNEGTVFTFKTNRDSPNYRLINIDFTDPEESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNILQLHDLATGALLKTFPLDVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTIQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQRAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSEQHFDWLIKYSPLHNVKLPDADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIDWIQ
The following text describes a protein:
Function:
Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.
Sequence:
MTGRRALTAAVGAVCRAAAPVECRLTAAAAAVPSLLVPTSPAALWTASESVQPSLRLAEEARALSHAHATTSSRGFFTAYTPASKVFRQRKLVGWTPEQLYAVVSRVEDYHLFVPWCQKSRVTRPPGPLPPPHQLRQQQQQQQHLRSQGAAAAAAGRAAGAAAATASGAGGGGVATADRAQGQGQGQGQAGPSYMEAELEVGFQLLVERYTSQIYLTPGRAVRSAVPDSSLFDHLDSTWTMEPGPAPATCWLSFHVDFAFRSQLHGYLADLFFSEVVKQMSNAFEGRCARLYGPSSLLSPPRPRTGGAAHTHTHTHQQHQQQPHTHTHQHPAHSSTARAGSSTSSSNSPARPMSPKAPAGSSGTDSGTGSPGKTAAAAAAAAGAVAAGR
The following text describes a protein:
Function:
Transcription factor that may play a role in flower development by repressing ANT. Regulates the transition of meristem identity from vegetative growth to flowering. Acts downstream of LFY and upstream of AP1. Directly activates AP1 to promote floral fate. Together with LFY and AP1 may constitute a regulatory network that contributes to an abrupt and robust meristem identity transition.
Subcellular Localization:
Nucleus.
Sequence:
MGRTPCCDKIGLKKGPWTPEEDEVLVAHIKKNGHGSWRTLPKLAGLLRCGKSCRLRWTNYLRPDIKRGPFTADEEKLVIQLHAILGNRWAAIAAQLPGRTDNEIKNLWNTHLKKRLLSMGLDPRTHEPLPSYGLAKQAPSSPTTRHMAQWESARVEAEARLSRESMLFSPSFYSGVVKTECDHFLRIWNSEIGEAFRNLAPLDESTITSQSPCSRATSTSSALLKSSTNSWGGKEVTVAIHGSDYSPYSNDLEDDSTDSALQLLLDFPISDDDMSFLEENIDSYSQAPPIGLVSMVSKF
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Sequence:
MGWVWLQAALPLGIIAGMLCVMGNAQFYIHKAAHGRPKHVGNDLWDVAMERRDKKLVESSSAASLN
The following text describes a protein:
Function:
NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.
Sequence:
MMRRASYCAGHAFTSLTVVGSRRFFQGERCEAEIVKLTKERGMFSDASVEASVHQLMSRLSDSPYVRHYTDAEVSAHAHGFLCAKARSALGEPFEHFHESDDSAFYICRKDQASQLRAVRQLTKFVSRERETKQSVSVRCYTAGDSDIAVFTAKIRPFVNPNPEKGETDIGQLASSAFLEERSPEMQERYQDLINRFHESVVPVHTVREVDGEVCFSMIMAADRSYYIATLQTVIQEIPGAVVTRCFSETFSNDTHVYTYFVRGATSQQLSDRASLVPFLPTRPRSLITRLHEDMVFDTEQTVYTDAAVIRLLLTPQPTSEDYRHLRSLVSKEPNGLSRLNNLRTTLSLEMMSERYILTLISTYPEFMKEIYEDFQVGTTHERRCAIREKITTRFREDQRSEHDLGIFNAFLQFNEVVLKHNFFKQHKVALCFRLDPSFLRSLGYPRVPHGVFLLAGAQWRGFHVRFTDIARGAVRMIFSKDTMYRRNKRSVFQENYNLALTQLLKNKDIPEGGSKGTILVSSRYLNTFNQPLCERIFLQYADALLDVVIPGEEGIVDRLKTPEIIFLGPDEHTAGTFPSVGSLFSKKRGYSAWKSFTTGKDASLGGIPTTILIAMTTRSVRTMVRGVYEKLGLDEASQTKFLTGGPDGDLGSNEILLSKEKTLAVLDISASLFDPEGLNKEELKRLATARKQLRDFDKSKLSSKGFLVLTGDKNVTLPDGTHVSDGVSFRDEFHLTKYSAADVFVPCGGRPRSVTLANVGRFLNLSAADNDSLLAGGSIQLKTPKYKIIVEGANLFISQDARLAIERCGIVLIKDASANKGGVTSSSLEVYAGVALSDEEHAQHMCVKDPNNVPEFYKKYVLDIIERIESNARREFEAIWREQQVQEGMPKTLIADSLSEKNVRVRASILSSDMCENKELVRYVLSNYTPKTLLEVVPLETLMERVPLEYQKAICAMWLASEYVYTTGISGNEFDFFTFMTKHMEQAKHIS
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MIRTIQRQSATRFSSALVQRRLYSLASDSLNKQRKPQEEGRLARIFKDPSNKAWKDLTAPQKAYRTSANIGNFSIVIFGGGVFGLIIYALVTSIWKGEAHYGDEAFELLKANEECRYVFGDHMKALGEATHPLRRTHGILTSRVWDHHGVEHLVLQFHLIGNERKGHVFGRLVNVQGDYKWEYLFVDVANYGKIIIFDHTNSVRQQHKNFGLWGSLKNITWGN
The following text describes a protein:
Function:
Together with eak-6 and sdf-9, negatively regulates dauer larva formation downstream of the insulin-like receptor daf-2 and in parallel with age-1, pdk-1 and akt-1.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MGQCLAVHRRIMASQEFPNIPQPESQCHDAFIRYSPGRYERRAARSQVDYYLLPQAPRLMTEDLDKKEFQRLYDARCELVECPAGRRAMQLDVQIYADRYEATLNKILETSQELDKGLEDIFQAYTKDDPLADKVMNCRLTVDEMGRVYEHFFRESAWNLDSFVEYRKNLARDAYLLLADLKIAIQRLGMHFNPNFEDAQVKVDFQIMQAEQIIFHFKRTYRDALKHNPDSITEFVEDELEDPGTPL
The following text describes a protein:
Function:
Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein.
Sequence:
MRRNTYDGRMKNMFNKIFLIVALIGVPLSVLGKTLHWPETIMFAVYCVTIIALAGFMGRATESLAIVSGPRIGGLLNATFGNAVELIISIFALQAGLIEVVLASLTGSVLGNLLLVGGSSFFVGGLKYKRQSFNVYDARHNSALLIFAVVVAFVIPEIFSMKMDAGKTYQLSIGVSIIMIIMYLAALLFKLVTHRGVYQHKSDEVAHEEEPEWSKGKALLILAIATLAVAYVSEALVHTFETVAKSFGWSELFIGVIIVAIVGNAAEHASAIIMAYKNKVNIAVEIAIGSTLQIAMFVAPVLVLLSMFFAQRMPLVFTIPELVSMITAVFLTIAISNDGDTNWFEGGTLLAAYVIMGIGFYLL