lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Acrosomal protein that maintains proacrosin (pro-ACR) as an enzymatically inactive zymogen in the acrosome. Involved also in the acrosome formation.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle, acrosome.
Sequence:
MLFIILLLSITTCAFSTPLPGSPLNEQEYEKFFSLLISESSAETLCTLRYLHGCGDRTIRRFDAYENHGVTPAGPICTNLESFSHFDSFCDFAKFRCAHRLFFAKRIPCEDDKVTTTQASDATPKQEVISVTSSLPTETPKITENGSSEKEERKLHSAEQKPMKAMYKSDESVKVNAPHLAKPKEKPLLSKLQAYLEAHPTTRKKPVKEQNEEEVLKIPYASQESSEEEDDDIRSFAGPKADISKAENNNQHKPVANKQKQKGSRAIPKKKELVLSKAQAYEMAQPTTGKKPVKEQNKEEVLKKPYASQESSEEEDDDIRSFVGPKADVSKLRQENNQHKAVANKQKQKGSRAIPKMNKLVLSKLQAYEMAKPTAINKSITEQNKEEVLNKPYASQESSEEEDNDIRSFVGLKSYVPPAT
The following text describes a protein:
Function:
Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTTFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSPKVDVSQQLETSTPLPTTQSSNRNGLTQHPGNSEGQSSNPPSAPMVTGDSVILKVLRSNIQHVLVYENLALQEKALACIPVQELKRRSQEKLSRARKLDKGPRNMDPQMGLPVCALVLLVGSCYRTQEPTCINQSTHLNEEDFLLLELLHWFKEEFFHWVNDMACSKCGGQTKSRGTSLFPSDDERKWGADRVEDHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDPCEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVISRRTKIKEELLRETINGLNKQRQISLSENRRKELLQRIIVELVEFISPRSPKPGELGGRISGSVAWRVARGEMGPESKEILFIPSEEEKISKQLHLCYNTVKNHYVRVSSNNRILDGWENGVWKMESIFRKVETDWNMVYLARKEGSSYAYISWKFECGSVGLKVDSISIRTSSQTFETGTVQWKLRSDTAQVELTGDKTLHSYHDFSGATEVILEAELSGGDGGVAWQHTQLFRQSLNDHEENCLEIIIKFIDL
The following text describes a protein:
Function:
Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. Allows utilization of gluthathione through subsequent cleavage of the Cys-Gly dipeptide by Cys-Gly metallodipeptidase DUG1.
Miscellaneous:
MISCELLANEOUS: Present with 1300 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTNDNSGIWVLGYGSLIYKPPSHYTHRIPAIIHGFARRFWQSSTDHRGTPANPGRVATLIPYEDIIRQTAFLKNVNLYSESAPIQDPDDLVTIGVVYYIPPEHAQEVREYLNVREQNGYTLHEVEVHLETNREHEAELGEALEQLPRHNKSGKRVLLTSVYIGTIDNEAFVGPETVDETAKVIAVSHGPSGSNYEYLAKLEQALAQMPIMKERGRITDHYLTALLETVNKYR
The following text describes a protein:
Function:
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
Sequence:
MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKMKNGMTVLMMGSADALPEEPSAKTVFVEDMTEEQLATAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSARETESSSASAVTPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMISFRSKFKDLEDKKVNQQPNANDKNSPPKEIKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKEDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEDSEQ
The following text describes a protein:
Function:
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.
Subcellular Localization:
Nucleus.
Sequence:
MDAFGGYFTDVKAERVENIFLEFLKSYRFDVKNSMGEDSYEAQIETMKVNESTTMFIDFSHVMRFNDLLQKAIADEYLRFEPYLKNACKRFVMEMNPTFISDDNPNKDINVAFYNIPFSKRLRELTTAEIGKLVSVTGVVTRTSEVRPELLQGTFRCLDCGGVIKNVEQQFKYTEPTICVNATCNNRMKWALLRQESKFADWQRVRMQETSKEIPAGSLPRSLDVILRHDIVEQARAGDTWRSKLCKVSVSQVCISFISLSFFLFSIFFFFFFLNAQRITIHRYTSGIVPRSVYTSGKSSSAAGLTATVAKEPETGEFCIEAGALMLADNGVCCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPAGGRYDKSKPLKYNVALPPAILSRFDLVYVMIDDPDDQVDYHIAHHIVRVHQKREEALAPAFTTAQLKRYIAYAKTLKPKLNSEARKLLVDSYVALRKGDTTPGSRVAYRMTVRQLEALIRLSEAIARSHLENQVQPRHVRLAVRLLKTSIISVESSEIDLSEFQDGNRDDIDGSDGGNDGAGQGDAQQNNAESGPTSGNTEGGVGSASQQGKKLVISEEYFQRVTQALVMRLRQHEESVTRDGTGLAGMKQGELIRWYIEQQNQKNSYSSVEEAKNEATKVKAIIESLIRREGYLIVVDDGRQPDAEGEGARQSVSRDNRILAVAPNYVVE
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MRFLSLGIHIHGDWEQVEEQETAEEEEEERFTSLVQEFFSAPAPSSNCSIKVNDMSSVVEGWLNELGIGWVLSSDDDYAASAGEELFRALDEIAQTLVLCLVRPLFPDHGEPVAEKSLPDQYHLALFIQETMLKMLVFVDFIVAVDPNNAAAITCEMMRAPYLKVSILLLVCNALFEASTKISLASHPPPYLQVQRIRDEMASLLSAKQDKTTEAIQGTLEDTWARIMGLIQDADPSPRLNGSSDIHEITRYVSFHIMYLWHNYWSLCPVVFQFQAESPSLGKHKKKLAKRSQCFLDRGLRYLFLINNLIYISGLHSSYVKAVLTRKIKDLVQTYLWETWEPVLSQPRCFWKNYSPLRKFRSAFQKNYNIQKQCKVPDPDVRQTLRKAITEKITSVLDDNCVSTPKFTHEKLEEMLQELFEG
The following text describes a protein:
Function:
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.
Sequence:
MNKGEGEGKNPGLMDCNKPWRGCLVPISQISCKNVKGKLVEVGKWPWQVSILFLGMNICSGSLIHHQWVVTAAHCLERSPESLQDSTFDLIAGDLPPTHGPLSVTRVRIHEDFINLISQDIALLKLKDPISWSPLIQPVCLPSPKLKPSLGSMCWVIGWGQTDTQVTSKPSYRLQEVAVRIVNNKICNEQYKFLFLKDQKKLIGSDMICASAQWGTDTCQVNSGGSLVCQVNKTWIQMGVMSWSFICRQRRLPGIYTSISHFTDWIKRQVNDVRFVSGARPAFLSPVFLTGYILLVSLGSLWLL
The following text describes a protein:
Function:
Catalyzes the tetrapolymerization of the monopyrrole porphobilinogen (PBG) into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Miscellaneous:
MISCELLANEOUS: The porphobilinogen subunits are added to the dipyrromethane group; MISCELLANEOUS: Present with 8480 molecules/cell in log phase SD medium.
Sequence:
MGPETLHIGGRKSKLAVIQSNHVLKLIEEKYPDYDCKVFTLQTLGDQIQFKPLYSFGGKALWTKELEDHLYHDDPSKKLDLIVHSLKDMPTLLPEGFELGGITKRVDPTDCLVMPFYSAYKSLDDLPDGGIVGTSSVRRSAQLKRKYPHLKFESVRGNIQTRLQKLDDPKSPYQCIILASAGLMRMGLENRITQRFHSDTMYHAVGQGALGIEIRKGDTKMMKILDEICDLNATICCLSERALMRTLEGGCSVPIGVESKYNEETKKLLLKAIVVDVEGTEAVEDEIEMLIENVKEDSMACGKILAERMIADGAKKILDEINLDRIK
The following text describes a protein:
Function:
May be involved in transcriptional regulation. May play a role in neuronal function; perhaps involved in protection of brain tissues from oxidative stress. May be involved in erythroid differentiation.
Subcellular Localization:
Nucleus.
Sequence:
MFQIPVQNLDNIRKVRKRVKGILVDIGLDSCKELMKDLKSFDPGEKYFYNTSWGDVSPWEPSGKKARYRTKPYCCSLCRYSTKVLTSLKNHLHRYHEDEADQELMIPCPNCPFSSQPRVVGKHFRMFHAPARKVQSYTVNILGETKTSRSDVISFTCLKCNFSNTLYYSMKKHVLVAHFNYLINSYFGLRTEETGEQPKASDPVSVDKILPFDKYYCKKCSAIASSQDALMYHILTSDAHRDLENKLRSVISEHIKRTGFLKQMHIAPKPVTHLALPPNSSAPSIAAPPPCFQLALPQNSQSSGTVQSVTVTPGTSGSLTHSPPTTAQSHVALVSSSLPVCQSSLSLQQSAPPPVFLSHSVALNQPVNTAVLPLTQPVGPVNKSVGTSILPVNQAMCSVNQAVRPGLLPLTKPMGPMNRPVGPAVLPMGPSVNSGVLQATSPGVISVGRAVPSGVLPAGQVTPAGVIPGQTATSGVLPTGQVVQSSTLPVGQTAPSRGLPPGQTVPLRVLPAGQVVPSGLLSSNQTVPSGVVPVNQGVNSGVLQLGQPVTPGVLPVGPPVRPGVLQLSPSVSTSILPMSQPVRAGTSQNTTFFTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPSGGGLAAVGPPPQVPVQFLPSGSGTQMGSSLPSLPSPQVLVSPAPSVFVQATPPLADANQALKQAKQWKTCPVCNELFPSNVYQVHMEVAHKQSEAQLCQVCNELFPANVYQVHMEVAHKQSESKSSEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSQEELMHHLLMHGLGCLFCPCTFHDVRGLVEHSRTKHLGKKRLSMDYSNRGFQLDLDANGNLLFPHLDFITILPREKLGEREVYLAILAGIHSKSLVPVYVKVRPQPEVAPKIPNKQKLTCPFCLSTFMTADAYELHLKERHHVMPTVHTMLRSPAFKCIHCCGVYTGNMTLGAIAVHLLRCRSAPKDSSSDLQVQPGFIESSELLMVNGDVIPESTFPVKRKLPEGHLGPEDQRDGEEPQLTLDADASSGSEKGLGAVPLKRQKSEIRTEGSGPSEDSLQALALDPSKYEGRSYEEKKQFLRDYFHRRPYPSRKEVELLSSLLWVWKIDVASFFGKRRYICMKAIKTHKPSVLLGFDMSELKNVKHRLNFGECESQKL
The following text describes a protein:
Function:
Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Deglycosylates a large and diverse number of proteins, such as CRYAB, ELK1, GSDMD, LMNB1 and TAB1. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro). Does not bind acetyl-CoA and does not have histone acetyltransferase activity.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MVHKEKPVDTQQLVVESSPSPVSGEPCVEAPGPVEDSGEVESTGHRKFISGVVEGFYGRPWTMEQRKELFRRQQKWGLNTYLYAPKDDYKHRMFWRELYSVEEAEQLMTLIAAAKEHGIEFIYAISPGLDITFSNQKEVSALKRKLDQVTHFGCKSFALLFDDIDHNMCPADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVPQSPYLHTVGEKLLPSIDVLWTGPKVVSKDIPVESIEEVSKILRRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFETNFVAIHTLATWYKSNMNGVRKDVVMTDGEESTVSIQIKLENEGSDEELETDVLYSPQIALKLALTEWLSEFRVPHQYNSRQVPQSGAKSTTIDVTSMTAPALCSSTSVTSVFQQPIMSPAIPPLCLDPLPLPITKAPQEVDVEKKDSDEEPMEMVVEKLDEPEPEVDPESKHAGPILNDKMAEDLKPMDTDKEGLVETKSPEESIQEDSGSDIAPMQTDDLLKQDVFVPGPNEKPLFIAEPLSLDDLCLLAELFYLPYEHGPKAMQMLKEFNWLRANSSVVSVNCKRKESEKVSEWQSRAQKFEDMCCSVIEMFTRLSNIANRTILYDLYPYIWDIKSIISMVKSFVLWLGCRSQSSAQFLRGDQEPWAFRGGLAGEFQRLLPIEAANDLFYQPPPSLPTSKIYTIRPYYPKDETAVYKICKEMYCEGMEDELFSQEDPDLIGDRLVGGLLTLSSDYGFVLEDEAGICGYAVGTVDVKPFIKKCKLSWLPFMQEKYNKPDCEKDLTEAEKMMLSFHEEEDGLPDSFLSNFPSLIKVDIHAKVTDPSVAKSMMGCLLSSLKANGSRGAFCKVRQTDKRMLDFYSKLGCFEVAKMEGFPKDIIIMGRSL
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MHSLAERGVPLEERQKANLSGLSDWDAARIFLEVVRSGSFRSAAERLSLSINAVRRRIDDFERQTGTTLFTRDVHGTHLTDEGTMVVSAVERMEAAAFDVLRTSDSTANVLSGEVRVAVTEGLGTFWLAPRLVEFQQAYPKILVDLHCAMRSADVSRHEADVAIHLSRPSALDVKLVRLGRMHLMFWASEKYIEKHGAPRSAMELIKHRLVLQFADQLAAKETFESFFPGVPERDLLVMKTNVSSANYWAVANGAGIGVFPSYAVALGGKLIPLEVELNRPLDIWLSYHPGSGRIPRVRHMIDWLIEAFNPARFPWFKEEFVHPHEFKDSYMGEPLTQLFGGFSTEER
The following text describes a protein:
Function:
Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity. Also negatively regulates the transcription of its own gene. Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector.
Sequence:
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDTSPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQASHNQVLVFTLQSLTDLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGHHLIRSAVPLEMNLS
The following text describes a protein:
Function:
Probable transporter.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MAGPDQHYEPAIDKRDFDDHRPLLHDIDTGIDGTGDGRLRSDSRLSAFRNLDGGSDGLLNDVVDEIVERDRRKMAMEVMRVCSFAVGVISCLGAGSITAFSLYGPLFLTRLHYSQLQVNAVSIAAEISMYLPVPLFGYLCDRYTPSPLALLSGLVFGGGYLLAAFAYRSGPLPEAGGEGWPPWVMVVAFVAIGTATSCMYLAAVTTCAKNFGRGKHKGIMLAVPIAGFGLSGMWQSQVATYLLCERREDGSRGDVDVFRYFLFLALFLFCLGVIGTFGLRIVDEEEDQYIDEAVEELERSGLLEESEFFRPRSEVQAAYGTFSDAADGDAPGPELSLTLSEEEREAARLEKEREEEERRKKNWLLNFETRLFLQDQTMWWLAVGFFLVTGPGEAYINNLGTIIQTLTPELHPPNAPSPAGLPSTHVTIIALTSTIARLLTGSLSDFFAPPATHLFPANIESGRRSSQSGPTAKRPTLSRLAFLLPSALLLSLGYLLLSSPLPLQHPGLSHVTTALIGLGYGSAFSLVPIIISVVWGVENFGTNWGIVAMVPAAGAAMWGVIYSRGYQDATDGGNGSPDGQCHGWRCYGFWAVGCTLSVWVAVVAWILAWRGWRRRGVVV
The following text describes a protein:
Function:
Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with Tcf7l1/Tcf3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways. Regulates the activity of mechanosensitive Piezo channel.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSQVSGQCPSRCDAPHGVPSAALDPAQTMSLLPGLEVARSTHPVEASSEEGFPEEAAPSMPHDSGLRAQQALNSIDLDVPTEAVTCQPQGNPQGCTPLLPNGSSHDHLSEPGSAGHAGNGALGGSKAHRKLQTHPSLGSQAGRKSRGSARSASQVPLQAQEGKAPAVRIHRQTASPTCCLRNAQLSGTALRSLRLESQGHRELNNKTLSQSNNKKPGVAAHAAIIPALTRPKQNCHDPSLLPGTHGVGKEF
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MNMLIIRFLALCILLRNANAAKNQHAVEFGALCNLFTLKDAADPPATEETSATFSELRTPIYNLNVSVADDDFLKDANGKYKDLMQGNDAAKLKAWQQHITEIINSKHGDENKQIYAKLTNKAQKASAQAIITQLIKQTDAIQEKYDAAQKTATESHAKAIEDILTAIYGDKDSKYTEGDFGGSRNSCGPTSNGNSAAGKNLLDDMICLCTNKAAATTTECGSATAPQVDGAGNTGQQAITHVISLCKSPAKPPALTGELIEARLAIFHSMLGRNPNGETGDEIRYVLGKYSASQCDGASEQNCVNYVAQLKTPGTGITWENKMRDAIEKLKAGQTASAALRHYRQQLKNLALTARNAYEAAKLATEGTTLPLPQTTPGVVEITETDTTCEKKGTGDECKPPCKVEGTGKDAKCKLNKEEAKKLEEKTEQKDGGDSKTTNTTGSNSFLIKTSLLTLAFLLF
The following text describes a protein:
Function:
Transcriptional regulator that plays a role in retinal development and maintenance.
Subcellular Localization:
Nucleus.
Sequence:
MPRRKQSHPQPVKCEGVKVDTEDSLDEGPGALVLESDLLLGQDLEFEEEEEEEEGDGNSDQLMGFERDSEGDSLGARPGLPYGLSDDESGGGRALSAESEVEEPARGPGEARGERPGPACQLCGGPTGEGPCCGAGGPGGGPLLPPRLLYSCRLCTFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRHTRTHTGEKPYRCPHCPFACSSLGNLRRHQRTHAGPPTPPCPTCGFRCCTPRPARPPSPTEQEGAVPRRPEDALLLPDLSLHVPPGGASFLPDCGQLRGEGEGLCGTGSEPLPELLFPWTCRGCGQELEEGEGSRLGAAMCGRCMRGEAGGGASGGPQGPSDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCNYSCNQSMNLKRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQKVHGHGGAGGPGLSASEGWAPPHSPPSVLSSRGPPALGTAGSRAVHTDSS
The following text describes a protein:
Function:
Acts as a catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MYSQTHQGQHVMMNGGQAHQRFGMQIPKFQSQSHHPHHTQQPHHHTHHNQASHNINHQHNFSSGALASATPHFTPSHIQNGAHTNVDEDIDESMNEHWQQQLQLAAESRQASSPHYHARSVAQQAKGIQIAPSQPETQEQVPDGQNGVVKAKASSRQGWHALDFGGQGLRALSTSLFNYIFLEKLYLNHNKLKALPPAIGQLRKLNHLDLSGNDLTELPEEIGMLTNLKKLYLFDNNIRTLPYEMGYLYRLETLGVEGNPLNDVLKSHIMKEGTKALIKYLKEEMPAFFFSCTTPLTLMAVHLPPPDRDWIVLDETASSSNHRTDKVTVLSYNTLCDSSATQSHYGYAPARVLSWEFRRELILNELRSHDSDIICLQEIDQGSYNEYFREQLAYNDYKGVYWPRGRAMGMQEEDAKCVDGCATFFKGSKFILLDKQLINFGQTAVRRPDAKGQDDIYNRLWQKDHIAVVVFLENRQTGARFIVVNAHLYWDPAFKDVKLIQTAILMEELTKLSETYAKWPPCTDKAAFRFSKEEGQSETPPLEEPAPSMQYASGDQIPLLMCGDLNSSPGSAAYNLIAHGRLDEEHPDLEKRLYGNLSKVGMTHPFKLKSAYGAIGELPFTNYTPDFKDILDYIWYSSNSLHVSALLGEVDKDYLQRVPGFPNYHFPSDHIALLAEFTVKGKKGKVVEADFGPQRN
The following text describes a protein:
Function:
May play a role in signal transduction pathways that involve calcium as a second messenger.
Sequence:
MQKHNLGSSKSSSKCTAVLPYQTPRLRDHYLLGKKLGQGQFGTTYLCTHKSTGKLYACKSIPKRKLLCKEDYDDVWREIQIMHHLSEHPNVVQIQGTYEDSVFVHLVMELCAGGELFDKIIQKGHYSEKEAAKLMKTIVGVVETCHSLGVMHRDLKPENFLFDTPGEDAEMKATDFGLSVFYKPGQTFHDVVGSPYYIAPELLCKIYGPQVDVWSAGVILYILLSGVPPFWAETESGIFRQILHGDLDFESEPWPTISESAKDLVKKMLERDPKQRISAHEVLCHPWILDDTVAPDQPLDSAVLTRLKHFSAMNKLKKMALRVIAERLSEEEIGGLKELFKMIDTDNSGTITYEELKDGLKQVGSNLMESEIKSLMESADIDNNGTIDYGEFLAATLHLNKMEREENLVAAFAYFDKDGSGYITIDELQQACKDFGLGEVHLDDMIKEIDQDNDGRIDYGEFVAMMKKGDDDQVGRSRTKKGNINFNIADAFGVKEESS
The following text describes a protein:
Function:
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MEHRVFTIANFFSSNHDFITGFFVVLTAVLMFLISLGASRKMQMVPMGLQNVYESIISAILSVAKDIIGEELARKYFPLAGTIALYVFFSNMIGIIPGFESPTASWSFTLVLALIVFFYYHFEGIRVQGFFKYFAHFAGPVKWLAPFMFPIEIISHFSRIVSLSFRLFGNIKGDDMFLLIMLLLVPWAVPVAPFMVLFFMGILQAFVFMILTYVYLAGAVLTDEGH
The following text describes a protein:
Function:
May play a role in apoptosis.
Sequence:
MEPPQCVEELEDDVFQPEDGEPGTQPGSLLSADLFAQSQLDCPLSRLQLFPLTHCCGPGLRPVSQEDKATQTLSPASPSQGVMLPCGVTEEPQRLFYGNAGYRLPLPASFPAGSALGEQPPEGQFLQHRAEVQIARKLQCIADQFHRLHMQQHQQNRDRAWRQVFLFLQNLALNRRENREGVGPW
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE).
Subcellular Localization:
Nucleus.
Sequence:
MGSKKRSPQHPASPAGGEVGAQAAGKATPVTAAPETAPVAVVPKPPDVAPFLTKVYDMVSDPATDAVISWSAGGGSFVIWDSHVFERDLLPRHFKHNHFTSFIRQLNTYGFHKVDPDRWEWANEGFIKGQKHLLKTIKRKKKSSQDVPSDLQSVPVKTAPGTENIEIGKYGGLEKEVETLKRDKALLMQQLVDLRQYQQTSSLEVQSLIQRLRVMEQNQQQMMALLAIVVHNPDFLNQLVQQQCRSNWWNDDGNRKRRFQALEHGPVDDSETSGGGAQIIQYCPPVPETSNQPTPANEAFCSSPVQSVSSHALEMPMDVEMASNNVGTLDSTGNDFTDTSALCEWDDMDIFGGGLEHILQQTEQDFQVDPLTIEDYGYDRPWLEQDCQVEAQQNCKNPQYADVITEA
The following text describes a protein:
Function:
Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF) which is a key building block for cell wall construction in Mycobacterium tuberculosis.
Sequence:
MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA
The following text describes a protein:
Function:
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Sequence:
MRQRTTIYNPYSSHDGIITNLNRTNFQLSSIPNHLFTIENKYTITTTTTQPNKSSLYSAIKELRIQTKFNNNESGIPIFSFHYEPGLNIYAVPQSNVDKLEFWQQVEQLIMELLGIKLSSQQWIANVNSFYYHDIQPQPLLNLKEGWKFNLHPKSNYDYIYNQDKIIIRELLTNVSEIEFNLESGIYKEIGLFLIDEKISTNDDLNLSGIRVILDEDSNTNNKEESIHKTMFHIKPRHRSFDDSTTITTTKIIPQGLHPILSTELNTTTIVIPTDFDVEECKFYYYLNLNKSLIFDQFQNIPIGSQLIINNGNKNLELPEYKINQWGNELLFEFEFDNDNDIPHHINLTVHSRYQLPQNNHSHSQISNVLNSLPNIFIGCNVKEGNLLDKSPFDTKRDVKIGGNYEIYFTEDTVFYHLQNSDNSGNSGSSTLLEINIPHGKTTFDRVNNITSLGLLIGVLMILYAISIRVFMSTTSKTKRD
The following text describes a protein:
Function:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
Subcellular Localization:
Nucleus.
Sequence:
MADSTTISCVKHIETYVDSSSSRSPSQQDASLDALAKLLLNDIITLELLVREMEMYLTTTDNIIRARGILLLAELLTRCSSKRVEDKTVHSLVGFFADRLADWRALRGALVGCLALMRRKTDIGAISSSDANAVAQSFMQNLQVQSLGQHDRKLCFEILECLMDSYPDTVMSMEDEFVYVICEAIDGEKDPQCLLLTFRLVERLAQLYPESSSSLASYAEDLFNILGSYFPIHFTHPKGEDDAKREELSRALMLAFASTPLFEPFAIPLLLEKLSSSLPSAKIESLKYLTYCMDKYHGNVIQEQHKPLWSSLKDIVLTSAPSSLTAGSRYEDNKVADEALVLVQKLIQQDNDSVSFLKLILNDADVNMTLKNLSNYNNYDDIAVTDKQRLNAVSRILHVSAAASVASCNAIFQSVFSELVNGLQSTMQEKDYTPGGLKFGYLYVCVDLLTACSTLVKPTDKTYLDKETWCTMLHSFCPLLTSSFVKTMKESTLDIYTHTGVRGLQILASFPANFSPVSKSTFEEILVEFTSVITLKFNNASIWRFVLNALVEIGSLIKKSDDSEKMASFDVIVVEKMLPLLSSDDLSMPFSLKVGAVSKIGMTNLKYMRKIVQELNTAISTNLQKYWLDGNSNSAEHAMLLLECYVDEVLPWFQNVKDNDNVPMHFALKIWNEIEDNTMFFDSLNDKKLLETTMNGMKRAVASCSEDSQSTILDKAFSILSSSTSFQVDESMQPAEYSCREEWIISLFDSVIIALRPKTQVKNTEEILQIITRALSNAHIPSAHALGSLFNKIPNDSLEEAMDITFNKYIVRFANGNGDNEIGVSNLRLSNVNDGLVTSDAIVVGLAWVGKGLLMRGHEKVKDVIKFFLNFLISNRSTSSGSVSSSEDCDDLTRAVADSFSIIMSDSEACLNRNLHATVKPLYKQRLFNMVMPILLAAIVKSDSPIPYKSMMHRAIAHVISNTPLSAIIGEAKKLIPLMVDGLTILSEDGKNRDIVYNLLLVLSGILTDKNGQEVIVENTYTVIMCLNKLVFYQHMMLVRETAIQCLTAMTELPYASVYRFRPEVLQTLSRALDDPKRSVRQEAVRWLQSHLEVFIFERAHLLILQCT
The following text describes a protein:
Function:
Proteolytically removes the C-terminal three residues of farnesylated proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MEFLQRLARFLDRPLFPWKKLIIGFSLANYFIEGFLGYRQYQVLKKTKVPKVLEHEVSQEVFDKSQAYGRAKAKFEFFSGIYGQIQNILFYQFDVLPKLWSFAGNLLVRFAPARFSGEISQSIVFVLSFVVISQILSLPTSLYHTFVLEEKFGFNKSSAKLWITDKIKSLFLTFVLTPPILAGFLAIVQKTGNQFFYYLWVFVAGLQVVMITIYPIFILPLFNKLSPLEEGELKSSVEDLAKKLKFPLSELHVIDGSKRSAHSNAYFFGMPWKKHIVIYDTLIEKSETQEVVAVLAHELGHWKLGHTTSLFGISQAHFFAIFSLFSVFINNNSLYADFGFHTVHPIIVGFLLFSDVLGPTDTLIKLGMNVLSRKFEFQADEFANKLGYNAELARSLIKLQIQNLSTMDADWMFATYHFSHPILTERLKALNWQSTGKVEGKEKAKDGEEKIDVATATGRDEL
The following text describes a protein:
Function:
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to specifically catalyze the sulfate conjugation of hydroxyjasmonates, with a preference for 12-hydroxyjasmonate over 11-hydroxyjasmonate. No activity with 12-hydroxyjasmonic acid methyl ester, cucurbic acid, 7-iso-cucurbic acid, 6-epi-cucurbic acid, 6-epi-7-iso-cucurbic acid and their methyl esters, prostaglandin E2, arachidonyl alcohol and 11-eicosenol.
Subcellular Localization:
Cytoplasm.
Sequence:
MATSSMKSIPMAIPSFSMCHKLELLKEGKTRDVPKAEEDEGLSCEFQEMLDSLPKERGWRTRYLYLFQGFWCQAKEIQAIMSFQKHFQSLENDVVLATIPKSGTTWLKALTFTILNRHRFDPVASSTNHPLFTSNPHDLVPFFEYKLYANGDVPDLSGLASPRTFATHLPFGSLKETIEKPGVKVVYLCRNPFDTFISSWHYTNNIKSESVSPVLLDQAFDLYCRGVIGFGPFWEHMLGYWRESLKRPEKVFFLRYEDLKDDIETNLKRLATFLELPFTEEEERKGVVKAIAELCSFENLKKLEVNKSNKSIKNFENRFLFRKGEVSDWVNYLSPSQVERLSALVDDKLGGSGLTFRLS
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
Sequence:
MVFVNPLANALTSIYNNEMRRNKQAIIMPASKLVINVLRVMQKEGYVGEFEYIDDGRWGKITVQLLGRVNKCGPITPRYPLSYRQMIALPDYVRRYLPSKEIGIIIVSTSKGVMSHKEAARLRIGGVALGYVY
The following text describes a protein:
Function:
Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAEDNDPESQTEDPTQKRLDEALERGDVAKSQEINTWFMIAGGTLVVSTFSGSVGSGLVTPMRNLLANSWMIKTDGRALLALLQQIEFAVLAAIGVPLLMLVLAAVAGNMLQHRLVWSAESLKPKFSKLSPAAGFKRIFGKQAAANFLKGLGKLIVLGVVMGTILWPERHRMEAMVRLDPAAMLGATTSLTIHLLGAVVAALAIIAIGDYFFQYRSWFQRQKMSLQEIKEEFKQSEGDPHIKGKIRQLRQQRAKKRMMAAVPKASVIITNPTHFSVALSYERGMQAPICVAKGVDNLAFKIREIAREHDIPIVENVPLARALYATVEIDQEIPTEHYHAVAEVIGYVMRLKRGFGAGRG