The following text describes a protein:
Function:
Probable ubiquitin ligase protein, which may be involved in mRNA export. E3 ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. Participates in mRNA export from the nucleus by regulating the transport of hnRNP proteins.
Subcellular Localization:
Nucleus.
Sequence:
MGKITKTMQQKHRDTLSPWLKEFVDTASSAPLPLILQRLDEFPRRWMFPRGDLYHWIPLLNRFDNILESICATYELSKGPQTRDFGRDVLLNNGGPSLEYRDEPWTVERLAEAGYKEDGDCQLLVAILKFTRMLLEHCGNRSIYASSHHIDRLLNSPYLEVQAAALEVGLELAQRYNASVKRMPSPPRSVNPTLLANHYNIDLEKVQLLARPFVRTPIVKSLEASSAAPAVSAGSTAKAKDKEKEKEKATGPKNVASMYANDLKALASSRPDEEDLWKSWGDLKMSYYPDTTNGEPSARDSKDAQPVEPRTTSSPAAPTPLRRSSTMNVSQSSRTQRVGSSEEGSPLKPSGAATDDRDGPKVVEIPRSVIESKRIYDLYDMCPSDMPATMKFEFTSRLRTCKALLGTHRERQLALAVRLLAITNLAYILPEAVFVDKVLKYDKDEPRTFQLVYQLAELIAPSPDGNPSEVPKWLQSITLALLEAISHQQEKHSDVLAALNVNVNHGILLYVIRIAVAEMKEDAPVDDQDELDADNWRGNLFGLTLQIAMATRIGQEMMTAGLMDCLVEILNLRTAVASRHYSMVLAFLDSLTYAYQTAFSQLNSAGGLDAITNLIVHTVGESKTLTEAGLGTKPELHASLVDYSIPFYHQQTLKWLLKFIHHVMANTYSFDGTNTERLLRNLVDNSSLLGSLCTIARQNRFFGTVVWSNATTLLSDFINNDPTSFAAISESGWIQAFLESVTNRPVSIPAEQPSLEPSQSRANDGSEGNDADDDSEDDGSAHDAAPDSDGQAATQPHPPTQEMLEAPRDFPPAHGILPSSESMNIIPTVLNSISLNNRGMKMVLSSGAIQSYMEIFESATHVQCMAHDPELASTIGSSLDELSRHHPALRPAIANAIIDMIARVTHLVKTMDATKACGARLEAPESSASPVAEPAQATEVKGKGKEKATDDTDVEMAEASSSSSGNNKPAQAPSIPYIQVLSTFLQPIISNSHLKGALISAGVIEILLDLAESPSLPHDFGETPACRMLVAAISQLIESAQIVGLPSLLFRMENTVKVLQPRINPTTTEPFFAPFLTLNSSVSPVQDEEPASEKRTPDVSSGTETVKALLNIQTMIKILYHCFPFSNRSQMVSMPAVNVYDYYIRLIQSLGPLLRGVLKEEAAVNGAVPHHWTLKNKPYQTNSLGSRTDVQDLLTDSAAQDSSANGKKLTPEEQSTAEYKNFQTLRVLLHSFMPSIFPFFQTIGKALLPRRNNNDPYIRSRHLAIAEASAETLIQQLQQSKAELTVRDIHNWIIMIHTFGEMVVDTNHRTASGGAFLILPVITAFKELGGFEALNVMLKRLADMVSTGATEGQEATKAKLSMIGMKKVLDIYCFIISGKNLSDSMAQIALAPKPTERTTREFSHQLVVELRMSILPVVREIWASNIIEKSTGTVVSKIIDIIKTIAAGDLESNAQSRSDKESLPHLFKNRESVPFKWISRKDAETLATEQGVDVDLALEALYRANGKESDTKEYIKYQKAHLVRNRNPVPAEDAFKEVPSPNLSSSAGMSLSNLLNTPTFPVSDLLGAEPMALDPVPNQPLGEASGETALGHATESSEDGSDEGQPGTSRETNVGASTTAPQQLPVLPSQQPATESQSNTPRITREDLVEERAKLYDTLIDRSLEVISSHPEAVFEVADLIQNTILKTDNEDRRVEVGEILANALMSFASDDADELKENGSSIAAYAHLLALLLQQTAFMRTTVDMLRDYVGDYLGFLKLPPASSNDSLPPWIPYILLIFEIMLFKDAQPPDIKWKQPVKEDDPIEESVIEVKEPNFLAEHRSSLLTTLLDFLPRIGKEESLAVSVLRILVVLTRDHAVAKIVGEKKNLQRLFVMAKQLCGAGSTRLKQTHISEHIRQILRHIIEDEETLRQIFETDIRHLMTSRQRPSAAPGLEPQAYLRTQAHLALRSPKTFVEVSTELLKLNRAVSHLGDGTLRSTPFLVLKERPADASVSPKESSVEPAVQATEDLTISDVKPSTEVTDKDMHDAPKNPAQDLKRPILEHPDGVVHFLLTELLNYKDVDERENVPAPPAAASKPESDATAANEATPSPSGDEQNSESKEKEKKLAKSPFKAEDHPIFIYRCFLLDCLAELLQSYNRAKVEFINFKRSAPVQANAPVKPRSSVLNYILNDLLCFSPASGVPESIAMKKKAATAVPARAVLVALVSKTGEKPQNRTHEPFEYDDEPDLLFIRRFVLDTILRAYKDASVSGEPADIRYGKMNALAELMAQMIGEGDKDSRPNNPRGTDPSIGRSQAQLKRLMYEKGYLTSLTASIADIDLTFPHNRAPLKPILAVIKTLSKTAVSMSQLGLIPASGTAGTDQAEDEFLSDGSSVSEDLTDDREETPDLYRNSTLGMLEPGRDDEFSDEDEDDDEDMYDDEQYDDELDYGDDMSQDNEDNPSDEEDDLGEMGEMGGMPGQPGVVEVLMGENDDEEDNDDMDDMDEDDEMDEDDEQELSDEDEDEEVGSEDMDDLEDDIHIVDEEGNAIDDDGASWDDGTDEDEEDEEELDYEAEAQNMQEAQLHNRRTFPEIMRAAMENAGDDLDAEPIRDFDGHYIDDDEDGEEDDDEDEGEDDMDDDMYFDGDGLHDDLLAPNMPSGLGWDIAIEPNHRHRPSRSPWPNSPFVVGRHRDAIDFQNFFRRPAHLSRHLPPPADVMSGTNPLLLPQSRREVPRHAHSQLVRLGITPNMIGGLGMGMGVEPLAFISDLVQHLPDVRLSAGGGPLALHFTADGPGGIIRELNAIPIPPPHSRESRPTEARRDTYQEPHQAVQFSPESTHERWQQEVKMIFGFGYQDKAQKLAPLILSKLTPAAIQAEKEEKARKAEADRKAEEERKKRQEEERKKREAKEAEEKAAREKKEAEERERLERERAEAAAQAAAQAAADQEANAVSQEAHPMEGVETQGPGENAEQQAEDERPRVYYTLRNQQIDITELGIDAEYLEALPEEFRDEVIAQAISTRRSQAREQVSQEGENTEVFQEFLEALPEELRNEILHQEQHEQRRRERQNAAGGQDLGPADMDPASILLTFPPGLRQQVLLDQGEDIMEHLGPELAAEARTLVARHRQLHAQQGGQAASRSRDAQRPTEAGAGTVQKIQKRTVVQMLDKQGIATLLRLMFVSQQGSIRSSLFSIFANLCENRQNRLDVISSLLQILQDGCANMDAVERSFAQISHKAKQLKEKDAKTPHPLKRSLTGGTNNNGQFPASSEVSPLLIVQQCLDLLVELSKLNPHIPSVFLTEHETVASTLKRSLSRKGKGKDVNGKAQKFAINSLLTLLDRSLVMESSAVMQVLADLLNKVTIPLQAIERRRKEAEEQAKKKKEAEEKAATEREAANAPEEQASTSTEQTPAQQEATQQPSESTPAAASGQQPAQQDQENKELEAPKEKADEKDVQSDEKKIRQLTPPTIPEHNLKLVINIFVARECSSKTFQNTISTIKNLSNIPGAKKVFGDELVRQARVLSENILSDLDNLLPHILKAESGTQIQGVALAKFSPGASEQNKLLRVLTALDHLFDSKSKKQDKPAEGENTKEDLLGSLYWNPTFGKMWDKLSACLSAIRQRDNMLNVATILLPLIESLMVVCKNTTLSDASAVSNANSQKEMLLTSPPPEDRIAGLFFTFTEEHRRILNELVRHNPKLMSGTFSLLVKNPKVLEFDNKRNYFNRSVHSKYQQTRHSFPPLQLQVRREHVFHDSFRSLYYKKADELKFGKLNIRFQGEEGVDAGGVTREWFQVLSRQMFDPNYVLFVPVSSDRTTFHPNKLSPINDEHLPFFKFIGRIIGKALYEGRLLECYFSRAVYKRILGKPVSVKDMESFDPDYYKSLVWMLENDITDIITETFSVEDDVFGEVKVVDLIENGRNIPVTEENKHEYVRLIVEHKLITSVKDQMKAFLTGFHEIIPEELIAIFNEQELELLISGLPDIDIDDWKANTEYHNYSAGAPQIQWFWRAVRSFDKEELAKLLQFVTGTSKVPLNGFKELEGMNGVSRFNIHRDYGSKDRLPSSHTCFNQLDLPEYENYETLRSQLLKAITAGSDYFGFA