lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Microtubule-binding protein that plays a crucial role in ensuring inner core protein localization within the centriole core, as well as in maintaining the microtubule wall integrity and the overall centriole roundness and stability. Required for efficient primary cilium formation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Sequence:
LHPYLNVFKHFKVEEWKRSTKEGDVTTYMDKALKGTVYRISGAVPASNYLQLPKTSTQSLGLTGRYLYILFKPAPAKYFVVHLDVATEDSQVVRISFSNLFKEFKSTATWLQFPFICEAAKGSVYEKTAKTSKRDLVGLAPSSVRWTCLMLDLRYILSLYLNRGYSHLKSVKLCANLLVKNLFTSDLLFDPGERALHGVSPMPREMAFPVPKGENWHDFYDYVRFPSDGSKMPFDSIQKGTLNPAAVAHVKDNPVSQLPKEVTLSKPVRDRVSLIQQITSPRERPRQSPLLTKNVPKIARTVSAPLQADRTCFREGLQSRSDSFLPSSPVDDGSIHVYAHKDGRVTVHSVSVDSDEFNKLSRITVIIAVLCFFVTQALWAAGGSVVVYPCHALIIAIALDSGKQTFLAGHTDKVSALAFNGNNTLLASAQIGQPSMMRLWDFPTGKCLCMFKAGMHSVSCLSFSYSGGVLCGTGKDKHGKTVVVVWNTIQVNHGGEAVMLAKAHTDVDIHTIKIAFFDDTRMVSCGRDNVRLWRVRSGALRSCPVNLGEYRSLDFTDLDFEAGQCEPDDRTLFVCSRSGHVLEIDYKNVAVRNARRLMPTEVQHSHRREKQTFNSGPGIALNSICLSSSFCATASEDGYLRLWPLDFSEVFLEAEHDYPLSSVRISPDNLKVLCTTATGNVGCLDIQSKDYCTIMRSHTDSVSAFSVEGSQKQLVTVSQDNTIRIWNLESMQQLYEFTASDEMPCTVSFHPSQHIFACGFDTGVVRTISLATSKLLEEHKQHRGLITGLTFSPDGNFMYSCCSRGTLALYNCAMQKSHIVRVLANVVSPDAGHGPDALSVSCDGQLLSLVGPSQYIVTLMDAHTLDELLRIDVSILDLDSTALDAAMRLCFAPFPLGHLLVTTSSQKVLVLDAKTGRLIRMIPQVHKQSCSSLAMSPDARYLLTAGDRAIKVWDYGMRFDVNSQVFIGHSEPIRQVRFTPDQRQVISVGDAIFLWDFLGSSIESDLEELQEDVTSRATDSPRQLVPVPTVVSPPCLELSSIQRLAEDKGDNKILKLKTVIGYNGNGRGNMVWNPDTGFFAYSCGCVLIVEDLHSGAQQHWLGHPEEISTLAVNHDAQVLASASGQGSGDSRCQIRIWSVQDKACRKVLFHHETQVQAMAYSRDDRLFVTLGDYVDRVLALWNAHTYDLMSSTCFSEPVHDVAFSLMSVGHLACVGKGTVTFWLTEQQGADISLKVYLPVPVPDAVGPAELTSLCYSTGCLLYTGTNTGQICAWDTETNRCFMTWEAVDGEIGILQCHGNRLVSGSNTKKIQLWSVLAVQELRVKGSSARSSSVLLEQEMTLDGTIVSAMFDNCMDMGIVGTTAGTLWYINWAENTSIRLISGHKNKVSEVAFSPQESHFATCGEDGSVRVWSLASMELVVQFQVLNQVITTNHIDHPIWSNSCLEGARADQDGNLLIIFILKKDGTHGPSVAHGQGMTFRVLTDHRSSPIHVIQCTRKQRSELGVEGGDLWLAASADRRVSVWVSDWMKDKCELIDWLSFPAPTGPEVTFCPWDRNILAYVGYGLQKEILFYSLQQKQVIETIPLPSFAMSLSLSPAAKIIVVGFSERLLRLIDHKVRTEQDYVGHDDAVGLCHFTPSGKQLFTASYNEILVWEVQVR
The following text describes a protein:
Function:
Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endomembrane system; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MKIVNMAADRTALFKASIKTVRTRNKALGVGKDSSKSTLLSHAQKMKDDFAIKAKEVVITISKLKDFLLEHRKQYINAASHLVNDSCHMSDAERDQIDSDAQDFMRTCSDTIRLFKTEAHRQNVPSQVRQHREVVFELIDAYLKGVCKLYSEQRAIRVKRVVDKKRISRLRQDGPSSKSKQSVSNNGDDQVKNNPPLDLHLTSQEEEDEELSPEEIRMFQQENQRLFNDMNCLVDEVRQIEGKVVEIAQLQEIFTDKVLQQSADIDRIGDTVVHTTENITAANQDIREAIKNNAGMRLWILFFLVVCSFSLLFLDWYS
The following text describes a protein:
Function:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis, it proteolytically cleaves poly(ADP-ribose) polymerase PARP1 at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9 (CASP6, CASP7 and CASP9, respectively). Cleaves and inactivates interleukin-18 (IL18). Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes (By similarity). Cleaves and inhibits serine/threonine-protein kinase AKT1 in response to oxidative stress. Acts as an inhibitor of type I interferon production during virus-induced apoptosis by mediating cleavage of antiviral proteins CGAS, IRF3 and MAVS, thereby preventing cytokine overproduction. Also involved in pyroptosis by mediating cleavage and activation of gasdermin-E (GSDME) (By similarity). Cleaves XRCC4 and phospholipid scramblase proteins XKR4, XKR8 and XKR9, leading to promote phosphatidylserine exposure on apoptotic cell surface (By similarity). Cleaves BIRC6 following inhibition of BIRC6-caspase binding by DIABLO/SMAC (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MDNNETSVDSKSINNFETKTIHGSKSMDSGIYLDSSYKMDYPEMGLCIIINNKNFHKSTGMSARNGTDVDAANLRETFMALKYEVRNKNDLTREEIMELMDSVSKEDHSKRSSFVCVILSHGDEGVIFGTNGPVDLKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDDDMACQKIPVEADFLYAYSTAPGYYSWRNSRDGSWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFESFSLDATFHAKKQIPCIVSMLTKELYFYH
The following text describes a protein:
Function:
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Sequence:
MLGDPSDFYRGKIFAGPMVRASNLPFRLMCLENGADGVYGPATSVDSILASHYDENEDPYTMYFGWPKNPHVHFHTDPKEKGKLIFQILTNDASKAVQAASVVVKFADAIDLNCGCPESFATSRGTGSSLMSEPEIVADVVSALRRNYNVPISVKHRIHHNIEESIQFAVACENAGASAIAVHGRLKEQKNKGSVAYDNMKLVFDHLHVAKIGNGGVKNREMAKEMMEKTGCESVIISSAALKNPTIFSGHPETDPVKLARRYLEIAKQYGCSDRHEYRWSVNTMLGKYRHITRSPDYEPFTHLEDLDKMIEYINRDGVFPMPQNPTETEDDD
The following text describes a protein:
Function:
Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Subcellular Localization:
Mitochondrion membrane. Nucleus. Secreted.
Sequence:
MAVALNLWLGRRVCAVVARCGFASRGVTTPGCTSREPDPDSDWEPEERELQEVESALKRQKKAIRFQKIRRQMEAPGAPPRTLTREAMEQIRYLHKEFAASWSVPRLAEGFDVSTDVIRRVLKSKFVPTLKQKLKQDQKVLKNVGLSRSFQQLPDSGDAWKPLSAGPSMSGSSLMPGEETSSKGHSQTTALKVIELNTYSTDTPRRQKGRNKGIQGLKEEKNFVPIATDLGHPRELQKSSTSDGEGTRGTHRDGLPNGKELKEWEAEESGDQNFSNKVVQRGREFFDSNGNFLYRI
The following text describes a protein:
Function:
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
Subcellular Localization:
Cytoplasm.
Sequence:
MHILVTNDDGIDSPGLWALAKAMRAAGARVSVVAPAEEQSAMSMALPPQTNRELRAIIPPAELDGMLAFAHNGSPVGCVTVAMLSGVLPPIDAVVAGINRGLNGGSNVMLSGTVGAAMIGALWGLPAMAVSLQYIGPEPMPWATAAYVAERLFPLLEQIRGQAPLVLNVNVPHVASPDDLRGFRQTRLSEFFFGHYLDIELNPTGPVERSQIIFRFARERVPDFDVDTDDGAVRAGYVSITPLRPLMNSSPLTLNLPDLHA
The following text describes a protein:
Function:
Catalyzes the deamimation of cytosine to uracil at position 8 of tRNA in 30 different tRNAs. This editing guarantees the proper folding and functionality of the tRNAs.
Sequence:
MKVSLAGQTVDVKKILNEIPKRTVTAALLEGGEIVAVEEADDEHAERKLVRRHDVEGKVVFVTARPCLYCARELAEAGVAGVVYLGRGRGLGPYYLARSGVEVVEVHPDEPLGYDPVDRLDVLLTFGGNPYLTEEDVAARVYCLLTGRGFDADIAPAPENLSGRVEIMVTRGDPDEAVELLKEELPVFRIRRFLISGEFDRDELRERILEDIEPRILDPFAVRARIARAGAFSSSREAEVFIGDVLTSVGREVNLNDPRTVVTVDVLGPRVSVGVEKR
The following text describes a protein:
Function:
Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile.
Sequence:
MFFKNIICPACGAACDDIQVEFKNGAIEAKNICKVGNARFKALTSSRRLKQPLIKFEGKLKSVSWDEALEKAADILVSAKRPLLFMGSDISCETHEIGLRIGEYLGAVVDSNTTLGNGPAAMGLQESGKTAATEGQKKNRGDLVVYWGTNPLESMPRQMSRYGVFPRGYWTGRGRFDRTVITVDPRKTLTSEASDLHVQLKPNSDYELISGLLTLLHGKTPHPSIEEVTGIPIFLMERMLYMMKNCNFGSISVGVGLSSSIGKHRNVEIAMNLVKELNNYTKFTLGVLRSHCNAAGFNQIASGMYGYPFGLDFMKGYPRYNPGEFTTADLLRERDVDAVFVIGTDLLNEVPADCAAYLSEIPLICLDIVPCPTIIVSDVVLPAVIDAMECDGTFYRLDDVAVHFEPFMDSSFEFTKSNEDTLKQLFVKIKEKCNYKPVKIS
The following text describes a protein:
Function:
May act synergistically with the Wnt pathways to control T-cell fate specification, gonad development, and P12 cell fate specification. Required for the distribution of pop-1 and tlp-1 proteins.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Cytoplasmic in neurons and nuclear in T-cells.
Sequence:
MFSPDTNSEFYDDFYTKYNTNMAPTTSTFNAQPRLSLDSGLGLTNDSFYSTDLNETHLMDISAGNASTSFQSQPPPQLESSPPTKWARIRTPPNRKKKISHEGPNQEALPPGFNLFSPPSRKKIKTAFSSPPPKSMKTPDSLRKSIRISSPSPFKVTFSKTPLKLSNNENVTGIHIGRSGTYYNKQVTGSASKRCLLPSKPDGFTFLGSPGNSDVLDFPLQTTFEGFGDLDTPAKINAALEVNNDDSMDYYQYAGMIETSSSLATYTNSTGPLVENHARNLKSVPISRTASRNLMKISRKSVEEPVPEPQAVHVEPVIEKPTKISAKKEKEQKKSAAKEAALKEAKEKEMRIWKLAPFETPKKEVPLYSGRWLVISTGRTLAQQELFSDAKSFFKANPPPAPRAPQAPELASGPRRIPTIQRVTLFKHRYRSPRD
The following text describes a protein:
Function:
Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response.
Sequence:
MSKKFVNKLEETVDDALFGLVASNKDIQFCKTSKRVIHRSQINTENVSLIAGGGSGHEPYAAGYVGKGLLTAAVAGNIFASPPSRNVQTSLEATKGKAGAILFVINYTGDRLNFGLAAERFNASGGNARVVTISDDVAIDNPNNRVGRRGLAGAVLTIKIAGAMSEEGRSLDEIYDMSQNVVNSLGTLGVSLYPGSQPGKDRETDLSNDQIEIGLGIHGEPGKLRASYESAHKIVSDVMATLKAKMEMKESDEFVVLVNNLGSVSQLEMGIVNGEVLRWFEMEKMKVTRFYSGTYMTSLDGHGISVTVLRADESMMKYLDAPAKAPGWVPSLSHRNQAEQSHSDKNAPIEVKSTGTSIHPDLVRECLNGVVKAMMDSEDQLNTLDAQSGDGDCGSTFASAARAIQKAEALDYEHLETLLKQLSVIFEQTVGGTSGALYALMFSAAAPELHEKIESNTILEALKKANHAVQKYGGARVGDRTMVDALDAMVEDLGKGLADNAGLDVFERAIQASENAAKETAHQKASVGRASYTSSESQTKPDAGATAISIWFRAFWTAFKEEMGKTNK
The following text describes a protein:
Function:
Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing OFP13 show small rosette size, late flowering, reduced fertilization and blunt-end siliques.
Subcellular Localization:
Nucleus.
Sequence:
MGKKKMKLSSLFKGGAGGLLAVPLCYNAKTLSFRVGDDMIKTVNSVFFDHHHNNNNGGDLLEAETPESWFTNSSETASHSTESDQDLDAESLEMVVRGVVRSERLFFDPGVTSSILEEIEEKSKSDLKSKETVAVGEDRSTPIEEISVAVAMESEDPYGDFRRSMEEMVTSHGELAKDWESLESMLAWYLRMNGRKSHGVIVSAFVDLLSGLSDSGAGITSASVSDSARYSTAVSSLPSSPVYSLSQGQTEIQEEERRSC
The following text describes a protein:
Function:
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but also occur in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Subcellular Localization:
Mitochondrion. Nucleus.
Sequence:
MNVSRMPKRYRDRMLHVLTPDPNEVKPDYITAMYQKPALKKLLYAWYGKKSGINPGILWPSVEELKDIIEFEKEWEPSLQDMLAKLREERELEMKEIKEKEKLVESRLAKMPQYIKEYRARLKKAEEQELQLKKKRQVLLDEARDYFGYQIDPNDPRFEQIKLAKEEEEKKMMKKKKKEEKLSNVAKFTGSPH
The following text describes a protein:
Function:
Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N-acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase.
Subcellular Localization:
Lysosome.
Sequence:
MAELGAEVWALSPLFIILCVSLCSAGCPCTDPSLCEPIKGTQDFEVLVFYTGGKNWKFYDWSQVTTIALFGKYDPELLCFAHSKGARLVLKGDVPLQDIVDPNNRTSWIKQKVELAKSQFMDGINLDIEQSVLKGSPEYYALTSLVQETTEAFHREIPGSQVTFDVAWSPDCVDGRCYNYTGIAESCDFLFVMSYDEQSQIWTECMAGANSPLYKTLSGYKKLIQLEIDPKKLLMGVPWYGYDYPCLELLEDNKCTIQKVPFRGAPCSDAAGRQIPYSKIMKQVNSSLTGRLWDDVQKSPFYNYKDAKGQLHQVWYDDPMSISLKSAYVKINGLRGIGMWNGDQLDYSRNPIAETQTKDMWNALKGAWL
The following text describes a protein:
Function:
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Sequence:
MRFYIETYGCSMNRSDSQIMEKLLEEAGLIRVNDPREADVIVLNTCNVKTPTEQRMIQRARELSKYAPLVVAGCMAKSQGYKLKDFSKVLVAPREIDKIVEAVNSAIAGRRAEFLEWRFIDKSSYLRDPLELVGIIPIAEGCMGACTYCITRLARGGLTSFPKRNILRLAEHFLRKGAVELWLTSEDTAAYGRDMGENLANLIMDLSDLPGDFRIRVGMMTPSSALPILSELIGAYRSRKVYKFFHLPVQSGSDRVLEDMGRNYTVDQFLSMVDFIRKELSDVSIATDIIVGFPTEDEEDFESTLAILERLKPDVVNVSKFGARPGTKAASMRKLPDAIVSRRSKEVNELVERIKEEVNERYLGRELEVLVSEKGEKGFQGRTNSYKPVALREVKLGHFYLVEIVDFRANYLIGEVKEELGKAGLQIELKLT
The following text describes a protein:
Function:
Plus end-directed motor protein involved in asymmetric cell division of sensory organ precursor (SOP) cells by playing a role in the asymmetric localization of Sara-expressing endosomes to the pIIa daughter cell but not to the pIIb cell. Targets Sara-expressing endosomes to the central spindle which is symmetrically arranged in early cell division. During late cytokinesis, central spindle asymmetry is generated by enrichment of Patronin on the pIIb side which protects microtubules from depolymerization by Klp10A while unprotected microtubules on the pIIa side are disassembled by Klp10A, leading to the asymmetric delivery of Sara-expressing endosomes to the pIIa daughter cell. Also plays a role in regulation of autophagosome formation, fusion and positioning and is required for normal localization of Rab14.
Subcellular Localization:
Early endosome.
Sequence:
MSSLKVAVRVRPFNSREIDMDAQLIMEMENKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWSFDAEDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNPGLIPRICEELFARMRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSLGPYVENLSQHAVSDFDEIQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSETVSKIHLVDLAGSERANATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYIPYRDSILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTVNEDTNVKLIRELREEINKLKSMLAGDIHSLQPSLKVLADLQKKEAQEKVLTEEWTEKWKVAQSILQEQKSLGLRKSGVGVVLDSEMPHLIGIHNDVTTGVTLYSLKEGETRIGSEDADVAQDIELAGDGIRAQHCSIFLKGGVVTLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRFNNPAEAAKLRKDLSRSQLDMSRLSLITSSKENLLTCSIYSDEDGASPYKRPERQYYPQRPMSRDDPELQDENRKILDTIENALKQLNVERVQMHDQYKTKVRKLTEELIRLEQEEMDGLQLLNCREQELIARKDMLLWEKNNEKVQIDIVCRQISAFQTQLDSKKRDFSEYVAKELQELQDCGKLDEMGMKIEEGTPLNDELLLQVSDSLDLFAAQFIKDTVRRNNEEIRKLDEQIAEKERILNASTTKIAKVDETMLEIQAQLERLRLERAESEAESQAMRAKKQNMKLQLGNKSMSTSTSTNEADDVSKSDTYETCDTFHTAQSNLSLVSSPTITEGQQSPLSNCSCDAEDEAEDTRKDDLSGSSEETSRTCTAGPSSGSGSGSVGIGGSGSAPSCTPSSQAIMSDSGVCLDSRNQAILQNGHLNNYKQAVRTSDEDTGSCSSCELGRHSDVARPYCPLHSLRRKIAAQKALIMKNLETDLNKAQLDEHIADLQDLQRRYIQMEQEMLQSVQDLEAHAQCCADERSGMERQYELASSIMRSSVMSPTSMEESTSQIYSPSMTRSCPSMREFPEGEHFITIPSFVMRGAGKQTHYEYEVRIALPDGKLNILRRYSRFRELHLCMKHCYGAKISALPFPRRELFASNSEPVAKHRRRLLELYLRRLFVVCSKIPQCPIYEGPGGTGLTRASLVQLSSFFKKGLFENGKHGTG
The following text describes a protein:
Function:
Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAHENVTFEPETGVVMTSFTTVHQNMTSFNNGDETNGKPYKERYLEEALAYENTEAIDENEMELANRRDEEVSIQSRNGKGSQDVAQVRVKDPPPTPPQWQLYMHIAFFAMCGCLCRIGTDKIFGTLAVIENSGEVVNLSFISNMVGSFVLGALNASPMGSTRLGAMYKGLTTGFCGSYTTWSKWNQQLSLALVGETNTVSQSQVLSIVSWFIGFHSFIGSYCVGLDFGKDVGGRIGKKVSPNGPKISNIAVAVLLFSAAAGFIVGVIVDPTQTGKSIWMAVLFAPFGACIRAYLAKYKYERFMLPLGTLLANLLGALVLAAIHVINVRAVTCGSGTICWGSVVTYGIGTGFCACLTTVSTFMSEIYKLRPANPKFAYGYAILTVVICQVLCGIINGINYNYDTY
The following text describes a protein:
Function:
Involved in a late step in sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. The lumenal sequestrated membrane proteins are targeted into the vacuole after fusion of the endosome with the vacuole (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Golgi apparatus. Endosome.
Sequence:
MSRLQIQLKLAASRIEILRQKEEALAKQARRNVALGLKSYSPALAKARIEPLIMQDIYIELLELLQVDVEILANRCVVLEKRAFNDSMSFKSSLYHVMAAAPQLQIKELRFVHDFLVKLYGKEFARLSDPDLATNDTAFYQLLYPPIPKDELVEAYRKELIRTYFPNDYPKEANKDIPSSAEADTMLNLESSENREQPTSLKEENTQEDDEKVNGNLANISKRAEPQNNGSTNASSLQSSNYLPTNPTLTHSNKAPSFEELAARLDRLKHL
The following text describes a protein:
Function:
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability. Involved in the behavioral responses to pentanol, hexanol, octanol, nonanol, propyl acetate, butyl acetate, isoamyl acetate, methyl caproate, anisole, heptanal, 2-heptanone, r-carvone, and nonanoic acid. Also responds to pyrazines.
Miscellaneous:
MISCELLANEOUS: The atypical heteromeric and topological design of the odorant receptors appears to be an insect-specific solution for odor recognition, making the OR/Orco complex an attractive target for the development of highly selective insect repellents to disrupt olfactory-mediated host-seeking behaviors of insect disease vectors. Odor-evoked OR currents are independent of known G-protein-coupled second messenger pathways.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLPRFLTASYPMERHYFMVPKFALSLIGFYPEQKRTVLVKLWSFFNFFILTYGCYAEAYYGIHYIPINIATALDALCPVASSILSLVKMVAIWWYQDELRSLIERVRFLTEQQKSKRKLGYKKRFYTLATQLTFLLLCCGFCTSTSYSVRHLIDNILRRTHGKDWIYETPFKMMFPDLLLRLPLYPITYILVHWHGYITVVCFVGADGFFLGFCLYFTVLLLCLQDDVCDLLEVENIEKSPSEAEEARIVREMEKLVDRHNEVAELTERLSGVMVEITLAHFVTSSLIIGTSVVDILLFSGLGIIVYVVYTCAVGVEIFLYCLGGSHIMEACSNLARSTFSSHWYGHSVRVQKMTLLMVARAQRVLTIKIPFFSPSLETLTSILRFTGSLIALAKSVI
The following text describes a protein:
Function:
Probable mitochondrial mRNA stabilization factor.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MIRVFLRQGRVLRPSTLQYRLRHFSDDKKPTQGLDFRALNNEIGGERQDKSSVENDNTPVSQAINGDIIGASSTSSETPSKPWYLRDQPEVKEEPVNIDLGLPDGAMNDIAKQLARDAIYDIKYIPEQDILIGSGKSSRHIYKAGREVMGVLKHQHDVLPTAEGLFKKNAQRMSYRRMLKKARKQNLEFPDSEWVVIDSQMGFHVHIFTAEKRELVNLEDLYKFEMDEEEVEISPEDFAWAEKGQKNVIDGDEFLSGQHNSDPFLRSDSITGLPKKPSNNPFDGGIGSGQRRSLHTSAPAATTLAVDFDGGSAAAKDDESKSHPSIIPLFMYQKWATQGDKDQVLAKYDDLQPHANRKEIVLSAITNFLKLPTTGFNDVPQAVEELFEVFSPSDASNPEWKEAFKALVNAYALNHKCVPTQALVDYLVAQQASGAAVVNWQVSEIVRATIDSTQYEQVGVTSLKEWQRVVDAKIQIIKQLIESFGLVAPVRLLANDRFIRRVARSLTQRTSASFGLDLVAKPETTKHPLDLRLKLLEESLPIKMLNRKTLFVFFAAYANSYAWNPFFKLLKRCHKETKTDNAHVQTIISLVLNSRDETAYYRLMESELGLLCDAQGELPLDKDIAVKLEKLMDNIDPEGRRFQQLRHKTNTQLYS
The following text describes a protein:
Function:
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
Sequence:
MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSASKKSANSAEEKAKKDDKPKKKVKKDEKVALVNRMGVDPYHGWKAQYEILSGKEKVVAELKALAENADHIYLATDLDREGEAIAWHLREVIGGDDKRFSRVVFNEITKNAIQQAFNQPGELNISRVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREKEIKAFVPEEYWELHADLVAKGDIPIQMEVTHAHGKPFKPVNREQTHAALTLLENARYKVLDREDKPTSSKPSAPFITSTLQQAASTRLSFGVKKTMMMAQRLYEAGHITYMRTDSTNLSQDALTMVRGYIGDNFGDKYLPATPNQYSSKENSQEAHEAIRPSDVNVLAEQLKDMEADAQRLYQLIWRQFVACQMPPAKYDSTTLTVQAGDFQLRAKGRTLRFDGWTKVMPALRKGDEDRTLPVIEVGSDLDLQKLIPSQHFTKPPARYSEASLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTARMESGLDQVANDQAEWKAVLDGFFAEFSEQLEKAEKDPEEGGMRPNQMVMTSIDCPTCGRQMGIRTASTGVFLGCSGYALPPKERCKTTINLVPDAEILNILEGDDAETNALRARRRCQKCGTAMDSYLIDNQRKLHVCGNNPACDGYEIEAGEFRIKGYEGPIVECEKCGSEMHLKMGRFGKYMGCTNDECKNTRKILRSGEVAPPKEDPVPLLELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEELVRFKDRLPEKLRYLADAPVVDKEGNKTLVRFSRKTKQQYVSSEKDGKATGWSAFYIDGKWVEAKK
The following text describes a protein:
Function:
Involved in the biosynthesis of phylloquinone (vitamin K1). Methyltransferase required for the conversion of 2-phytyl-1,4-beta-naphthoquinol to phylloquinol.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MRCLESSQRGVALGRGRAAAPFRRVHSSVRLGVVRVATDDAALPGPQGAFVPGQEAEARQGIFNRIAPVYDELNNNLSFGQHWVWKQMTVKWSGAKPGGKALDVCCGSGDIAFLLSRAVGTKGEVTGLDFAAEMLEDASARQDEQRREGTAQGRANITWVQGDAMDLPFESASFDAATMGYGLRNVASIPTALKELHRVLRPGCAVAILDFNNCTDPIPDAMQAFFLEQLVVPAARRYGLAAEYEYLRPSIKRFPTGPEQVRLAREAGFAAARHYPIGFDLMGVLVATKGR
The following text describes a protein:
Function:
Polygalacturonase not involved in the final stages of pod shatter.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MRRLSGILVIYIISTVLFGHFTNVARARYHYHKGRHGVTHPLPPPPPPPLETANPPDQVPSDPYPSPDPAPGDSDSGCVFDVTSFGAVGDGSCDDTAAFQDAWKAACAVESGVVLAPEGGVFKITSTIFSGPCKPGLVFQLDGVLMPPDGPEEWPEKDNKNQWLVFYRLDGFTFSGKGTVEGNGQKWWDLPCKPHRGPDGSSSSGPCASPTMIRFFMSNNIEVKGLRIQNSPQFHMKFDGCQGVLINEIQISSPKLSPNTDGIHLGNTRSVGIYNSVVSNGDDCISIGTGCSDVDIQGVTCGPSHGISIGSLGVHNSQACVSNITVRNTVIRDSDNGLRVKTWQGGTGSVSNLLFENIQMENVLNCIIVDQYYCQSKDCRNETSAVKVFDVEYRNIKGTYDVRSPPIHFACSDTVACTNITMSEVELLPEEGELVDDPFCWNAYGKQETLTIPPIDCLLDGSPVVEEAYDSNYGC
The following text describes a protein:
Function:
Has a role in the homologous recombination repair (HRR) of genomic DNA during meiosis. Required for rad-51 recruitment onto ssDNA gaps generated at stalled replication fork barriers (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MDSSKITFEYETAYELLVRLGADGLFLHTSLPTLNKVLELVPGKCYELDGDIGSGKTQLCYSLAAKLLLTKKTAKIGWISAVPLRTDHLSQHISSTDADETSHLLDRIVCKRVEMVSELRDSLNALCETINMQLVIVENIDAILHDTAYDREMGRNVQIDISERLRKLTRSGITVMVTNHITYWRGYPAPALGNFWASQIENRFFVERRSEESNVRSVSTMRGGNEKTIRVDFEISDGGLKAVV
The following text describes a protein:
Function:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
Subcellular Localization:
Nucleus.
Sequence:
MALESMGLELAIAKALADGSAVIGTVRPGMDLSVAALSTTTANKSDSTPVPVTTGVDDIINELNNGRSSLLKLIECLGPILTHAEPFQRASGVALLSTVISQTETSKISAQSATVLSQFYLSRLDDQPSVEPVLNGLLAMVSLSVLSKEEKTAIPARIFSELNVQSFQQSVRQTVFRLFAKLFETNLDGLHELGSEFVFGFIHAMDGEKDPRILILAFRIAQLIIKHLDFSKHAEDLFEVVFCYFPITFRPIPGDPYGVTAEDLKHELCATVAATPLFAPFAVPVLLEKLSSDSAAAKVTHRLSFHTFVFYNAIHNIDFCVLKRDAMDAVSACAPVYEGASFSPYIDAFWDALKKEIVSPVEPANELSSLMAIRALVKSLSTAISISQKRQSPLEKMIDIILKDCLENLADPDLKFAKPCGKIMMSAASASEPACNIIVEKALPVILNALSNEDAPSKRKTLADVLGDFLVAGRSVYSSKNGTSDDLMQTPLKLYCEQLFDFFMPCALSDLYVPLKLSSLRGLTEMLLSRNLLGAKEECAVLELVLSWMLEDPNTQIHSVALETITSISAEIPDLVQNVVLEPLLNALKAAQTEFNVLKMESALVSCFALSKNKQMRSVILSALIDIFVSAATSTLESHPNMPYILAYERRTLQIVAEILLESSTQPIMLTLDQTHTCELIFKLVLTSVNTAPAMDETMKNEIVCLVAKVVALMIRSLDVPHQSQIIKELKHSFQSFNSPVVLTDPVYAYLTAAVMTNVSSKTPFDILDLEVYSNELINMSIQLDGLYALATSKILASIVNKGHGVQGIDAFVTHFCQTKCDSALVAVHCTLPQRQTILKVYSWIAKALVVKADPRGYQMTLQILGLLSNADLGLAAADAINVLISDDSQGVLTKMAGANIKMLYKQRLYNYCLPIVSSGFQVASDGSRNAYLYSLSHLLHNVSKGVLLSELPKLLPMLLHSLTLNETTLKLGTLDTLQQMVKDAPAVLESQISSIMTLLLPMCLFKNANQGNDARVRVSAIAILGLLMSWVNYTVLHPFKPRVLQELAYALDDPKRVVRKEAANTRSIWFMPQPT