lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface.
Sequence:
MAALDRSMARVEFDPDGNITDANENFLTLLGYRRDEILGKPHRQLCDGAYAQSEDYRRFWERLRRGEHFSGRCKRITREGRPLWLEATYNPVRDGQGRLLKVVKYASDIDAIVHQEHEMQSKLDALSRSMAMIEFDLDGNVLAANDNFLATMGYGRAELASANHRQFCEPGYRDGPQYADLWRRLNRGEYVTGQFRRVHRNGQPVWLEASYNPVYDADGKLYKVVKFASDVSDRMRRYQAEADNAHQAHTLSTETRTVAEHGALIIQSAVEEMLKIANTLDASSLNIGELSQHSQQITSIVNTIREIAEQTNLLALNAAIEAARAGDQGRGFAVVADEVRQLAERTSKSTKEIADMIGRIQTGTRSVIDDMQHSQEQARRGVELANEAGAAILGIRESTHKVVEAVQQFSRTLNADL
The following text describes a protein:
Function:
Out proteins are required for the translocation of pectate lyases and cellulases across the outer membrane.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Sequence:
MHVSSLKVVLFGVCCLSLAACQTPAPVKNTASRSAASVPANEQISQLASLVAASKYLRVQCERSDLPDDGTILKTAVNVAVQKGWDTGRYQSLPQLSENLYQGLLKDGTPKATQCSSFNRTMTPFLDAMRTVR
The following text describes a protein:
Function:
May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The PH domain mediates interactions with PSMD1 and ubiquitin. Preferential binding to the proximal subunit of K48-linked diubiquitin allows UCHL5 access to the distal subunit (By similarity).
Sequence:
MFGRQSGLGSSSNSSNLVEFRAGRMNMVGKMVHPDPRKGLVYMTQSDDGLMHFCWKDRTSGKVEDDLIVFPDDFEYKRVDQCKTGRVYVLKFKSSTRRMFFWMQEPKTDKDDEQCRRINELLNNPPSAHQRGGGGSNDGDLQYMLNNMSQQQLMQLFGGVGQMGGLSSLLGQMNSRTPSSRNTSSSGGGGASALQTPENVSVPRTPSAPSKSGSSRSSSNVNSQVGEGAGSSVDADAPGRSLNIDLSTALPGADAINQIIADPEHVKTLIVHLPESEDVDDDRKQQIKDNITSPQFQQALAQFSSALQSAQLGPVIKQFELSNEAVAAAFSGNLEDFVRALEKSLPPGATMGGKPSASEKKASDPETPTSVARDENTDPATEKQEEKQK
The following text describes a protein:
Function:
May serve the following two functions: a classical role as a yolk protein precursor and probably shuttle iron to developing germ cells.
Subcellular Localization:
Secreted.
Sequence:
MRAAILFCLVASSMAVPSGSLGSRPGTCPPQPSDQVMIEATRCSYVYGLTWDWNCNSQGQENYKCCQYENDIRICVPPIPADVDEEVGVEQPSQSVDQVRQAIQKTQDFIRKVGLYPAPDQRRRTTPTPDTVRWCVSSRCQMTKCQRMVSEFTYSPNMVPRKQWKCTQATSQEQCMFWIEQGWADIMTTREGQVYSANTTFNLKPIAYETTINDQQPEIQILKHYQNVTFALKSSRLVNPNTFSELRDKTTCHAGIDMPDFDMPASFADPVCNLIKEGVIPVTGNYIESFSDFVQESCVPGVLNMTYNKNGTYPLSLVTLCEDQQYKYSGIKGALSCLESGKGQVTFVDQKVIKKIMSDPNVRDNFQVVCRDESRPLDEEIFTDVTCHVGHTARPTIFINKNNTQQKETDIKTLVVKMMELYGNTDRDVNFNIFDSSVYDCGKCQMTGKPLNKNLIFLEESNTMKIVDDSKVYAGEVYAAYNVCSKLVPKPRAKICVTNVTEYEACRRFKGIAENIPEVKKVAWGCVLANSSIECMQAVHNNTADLFKANPMETFIAGKEFLLDPLMSVHRNDSVTMNHTYTRTLAVIKRSSLAKFPGLLSVPEGQPKYIKDLWKLKICSAGLKNFSAFHSPIGYLLANGTIPRIGSVFESVNRYFQATCVPEIEPETWRLDSDLLLGREMNWGFSSLNMYNFTGQEWLLWNTPATWNFLTYNRKVSTGLDIKKLIELKKQNLTSHIFNQNLSSPRNVELLDDLVGVEGISDLVKGVQDTIGPEGKQKMNMLRDRLSNSFPNFEAVRTLSDKVDIVNKMKDARQQRLQNKDHPFGNVIQETFQGHLMVDVFSKLLELRSDKISTLEEIISHVKTIPYLTDFKDVEITTVLKHPAIMSYVEIYFPRLSQTFVEPFDNVELREREFNRYTNPLWLSPKVHTYLDLVKNHQTEITKTCNSNLPLNFKGYEGALRCLKSGVADLASSTSRPSVTRTLRDTDLSTGWVHLQRPPPSLPQRQVVEIDVNMDIAKVCNFGEVMNPVLVTAYNTSGSWRWNITKALMIAHQSVALPALFGEGTVMGKDYDMLLPIAPLNQSYQPFLGSKPLRSMEAIVKASSYDWFKDQTGICYGETYTNIVKQRNETCQAIVKDVTCVGTPRMKKISVGRFGAKQFKMIKMCSRPSKFVRKMADFQCDNGFGYLKPVITAVACECMLCEEMIEYNTSFTEDNMWSDVSNKYVLTGEQDIYRQIPIWGNNSYFYDHTLNKNFELGNHSIIVEHVQTVVVERPSPGILSQVNSEVDPEVQVQMDSASLTKTCETVWNGQSWLPERFQGYKTSGSCVVPETGANAKSRVDRFRQIMQRKQQLVDHHH
The following text describes a protein:
Function:
Substrate targeting component of a cullin-RING-based E3 ubiquitin-protein ligase complex RTT101(MMS1-CRT10). RTT101(MMS1-CRT10) may regulate nucleotide synthesis through transcriptional regulation of RNR genes encoding ribonucleotide reductases.
Miscellaneous:
MISCELLANEOUS: Present with 125 molecules/cell in log phase SD medium.
Sequence:
MPPQIPNENDDLFTRWLKSRAIIQRAVSTRECFDSEVFLASGGWNITNEIITLKKYYQLKWPNSSCNSFHPKTVEFIKERLHNLEEHDSSWKIPNPAYSFKKAFLEDTKSAFSNLEPVWGPSRLLNPAELLLPQDEKLLVQEIPLEFAPFQYTNRFAYGGLQFKNNLFVTYGSYSFLAAGQCVEVHNFDILLNVSSLEICHALLPVIIPDDGDVRNFRNSSYVKFKDTQFNSIPELCSINFMKICNFMHQDFLLACGDNGIVYIWEINKVIKIFNKFTSDILGGKDNSRERYINVDPYMVLRVEESCWSVDVIDINGIIYIAVGHNKPGVTVFAFDKDVKKERRYIRPLDLPSSHNVPCVNFVPNSKDSVGYITLSYCSIFGNVVTVKLKEHDCTILTSFLDTQFFGDDLWTITPLTKKDFAKVDNFELLNLNYQDGFKESMLYSICRDDFLLGYYCDNAYLSGNFGIGTLLNQFQVPVTDLRLTSSAGIPDEVIPLRFTSFDRNYTTTGSIKYEYSREDFALILHAGDLDDMNDAVTKNTSCEQHLHQWTFWEDSGYKHYRATERGFSKYKDIINTFPQLITPSGRNKTSQYQNTSGRKICEPSTYKLTDLENDIEDISREFNRSIRNLKMDKQRQLRTSKEFKSLSSVNHIPNIESGNFLWYNTDAAADWRTLFGKDLNTVLKDPEICSLQLNSTEEDDVNSDPENEESGSSLTSFQRRYRDTEQRAHLKSESQKSWGFHNYVRNVKRLLESAVPGSEDSPLGYQLSEMHDEFFFLTTAHRLVLMKANPLIIISATHHEIFPLDGVVTCASKSLLQALNRINFVCHIKELNCIAVASQLGLISLLRLTEYRGIYSFRQEYILGWEVQDPVNPSPECRCNRNLFDAPMYGADGESSDTYCGVCDVYFPMGDICGLDYTYASDSEELKRKGYATLYVASRGSLRAFKITTEHGTTQQ
The following text describes a protein:
Function:
High affinity molybdate transporter. Unable to transport sulfate.
Miscellaneous:
MISCELLANEOUS: The amino-acid substitution Asp-429 to Val observed in cv. Landsberg erecta may decrease the molybdate transport activity. A 54-bp deletion in the promoter of MOT1 is strongly associated with the decreased expression of the gene and the resulting low molybdate content observed in several cultivars.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein. Note= shows a localization in the mitochondrial membrane while shows a plasma membrane and endomembrane system localization.
Sequence:
MESQSQRGQHETPKRSRFTGMFHKLKTNLVFRSKLAEINGAMGDLGTYIPIVLALTLAKDLDLGTTLIFTGIYNAITGAVYGVPMPVQPMKSIAAVAISSTAEDFGIPEIMAAGICTGGILFVLGISGLMQLVFNIIPLSVVRGIQLSQGLAFAMSAVKYIRKEQNFSKSKSVGDRPWLGLDGLVLALVCVLFIVLVNGDGEEEEEEEEGDGSRGRGRWGSVRKVIANVPSALLIFLLGVVLAFIRKPSIVHDIKFGPSKMKIVRISRKAWRNGFLKGTVPQLPLSVLNSVVAVCKLSYDLFPEKEFSAASVSMTVGLMNMVGCWFGAMPTCHGAGGLAGQYKFGGRSGGCVALLGVAKLVLGLVLGGSLVGILEKFPVGVLGALLLFAGVELAMAARDMNTKGDAFVMLMCTSVSLGSNAAIGFVAGDLLYVVLWMRNYGRAKPSSLPPQSGEHA
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MARPAPSPLLLLVVLAGALAGGGEAALLKAHFYRPSCPAAEAVVRDIVLARVAADPAALPARLLRLFFHDCFVRGCDASLLIDSTAGNTAEKDAGPNGSLGGFDIIDTAKAVLEAVCPGVVSCADIVALAARDAISFQFGRDLWDVQLGRRDGVVSSASEALSNIPSPSDNFPPSRPNSPARASTSRTSSFSRRAHHRRRPLQPLRQPPLQLHHHRCCPRHRPDPQRRLRHSAARRVWVALQQRHRRAYGPRQPCPVRLPLLRQPQARPWPVPLRRRTAADRRAAGMIHALTKEGYFLQEFKNAVRKMGRVGVLTGGQGEIRRNCRAVNS
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MIESQRHSYHLVDPSPWPISGSLGALATTIGGVMYMHSFQGGATLLNLGLIFILYTMFVWWRDVLRESTLEGHHTKVVQLGPRYGFILFIVLEVMFLFALFRASSHSSLAPTVEIGGIWPPKGIAVLDPREIPFLNTLIPLLSGAVVTWAHHAILAGKEKRAVYA
The following text describes a protein:
Function:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MSSETKRGRPPTRRQHLFTKDLKSLMFAFGDDINPAPDSVNVLEEIVVDYINEMCLEAARIAGNRNKVKVDDFKFALRNDSKKLGRVEELLVLQKVIADARRIVDCNADT
The following text describes a protein:
Function:
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
Sequence:
MTPTPSTTPHPAILYALPKDKVARSLGDFVIKAQEEALSKRSKFTLAVSGGSLAKTLVEGLTGRAEVKWEKWVVFLADERVVPLDHEDSNYRIVHEGLFSQVPIPTENIHPISTDHLDDPEEVAHDYEKQLMNEFAGKNAVAFPRFDLILLGTGPDGHTCSLFPGHELLKEDSTWVSWLNDSPKPPSTRITLTYPVLNHAHKVAFVAVGDSKKGVIHNVLDLPELGLPSSLVKPIPPGQVFWFVDEAAASLTQYVKTDFKL
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Sequence:
MVHYKLYYFPSRSVAEPVRQMFAYAGVEYEDIRITKEEWLANWKNKMAFDQVPVLEVDGQQLPQSLAIGRFVAKQYGFYGKTPFEAAWIDAIADQFKDYWVALAPWFYVHMGYAEGDVEAARAKHAAPAREMLFPHLQKLLKESKSGFLIGDQVSWIDFMIQEHVTVLEEEFPGYLKDYPEVFVHAAKIRALPAIKAWIEKRPPVIKHNNKSSNLFTVPIEEEELLDIGNAGQPFVSCIVADDKGATHTEECPIEQGYIRFFLVRPRSVGCMALWKGSVLVKQGCFSGQDLESSVQEEIVHLFILKQICRILLLFRRSMSAYKLTYFDVREFAEVSRQLFHLSDTPFVDHRLPREQWGDLKSTMPFEKVPVLEMDGFFLSHSQSPAISRENLISLIIVACFAGRSNLEAAWIDAYADQFKDYMEYIRPFYRAAMGGRRAKVTDEEKEELKKKFPEPNRDNFFGALERVAKENGLNGHLVGSSLSWFDLVIADHILTMENFVPGFIDGFPTVKETREKIVNTPKLNEWMEKRPVNRF
The following text describes a protein:
Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence:
MSCCGGNCGCGSGCKCGSGCGGCNMYPNLTFSDETTTTNTSVFGLAPAMKNQYEASGEGNAENDACKCGSDCKCDPCTYIKDPEYPMQSLEDLRIVTEESVEVDDDKSYVRITFRPTVPHCHLPNLIGVCIYAKLLKSLPGRFKVDVRVAPGSHATEASVNKRLGDKERIAAALENPDIMSLLN
The following text describes a protein:
Function:
May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation.
Miscellaneous:
MISCELLANEOUS: Overexpression of DivIVA is lethal.
Subcellular Localization:
Cytoplasm. Note=Localized at the cell division site and found exclusively at the cell pole during sporulation.
Sequence:
MPLTPNDIHNKTFTKSFRGYDEDEVNEFLAQVRKDYEIVLRKKTELEAKVNELDERIGHFANIEETLNKSILVAQEAAEDVKRNSQKEAKLIVREAEKNADRIINESLSKSRKIAMEIEELKKQSKVFRTRFQMLIEAQLDLLKNDDWDHLLEYEVDAVFEEKE
The following text describes a protein:
Function:
Syntaxin required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MMSDLTPIFRKYVAVIDDARNEQNGIDDHVERKQEDFGNSNETCEMFRDSFIKECARLLKFLVELNKVIKQIEKNYLDDFNMSDAEKDEFDMECRLQIQQYFKKFEFLENYEMERHNLSLKRFQSKSHRWSKILSNKNDNTKHVIHPQDIENGVYEFRLGVLRCLNLWIKYVSSKFTTIQQERLILENKMNFNSTPMPTLSNNADDFSADAIDISVSQSAPVETVQDEVKHYEETISKLTQEQLQVLETEHSELLNQKNEQLKKVETINKTILDIVNIQNELSNHLTVQSQNINLMLNNQDDIELNIKKGNKELRKAKRAAGRTAKMTTYGAIIMGVFILFLDYVG
The following text describes a protein:
Function:
May be involved in extracellular digestion.
Subcellular Localization:
Secreted.
Sequence:
MTRSIKVYDDIIISIIKIDDYDIEKQYYYIMEKTILAIGLLMLVGTLYNVQSTPELQLAAQFTNYQATFNKQYSGSELLYRLQVYEANLADIKARNQKLGREIFGETQFTDLTDEEFAATYLTLKVNPDDLEVPKAQFENVNATPIDWRTRGAVNKVKDQGQCGSCWAFSTTGVLEGFYKVQTGELPDLSEQQLVDCSTLIDFNQGCDGGMPSRALNYVKRNGLTTQDAYPYEHIQNKSCKIKGGAYKVAGSTAIAANEAAHQAALQNGPISVAVKASDWKNYKPKGDDFIFPDSACTGDVNHAVLAVGFTSEALIVKNSWNTVWGVDGYIYLQGGKNTCSVWDNSVVPK
The following text describes a protein:
Function:
VIP is a neuropeptide involved in a diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VPR1) and VIP receptor 2 (VPR2). Abundantly expressed throughout the CNS and peripheral nervous systems where they primarily exert neuroprotective and immune modulatory roles. Also causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
Subcellular Localization:
Secreted.
Sequence:
KRHSDAVFTDNYSRFRKQMAVKKYLNSVLTGKRSQEELNPSKLRDEAEILEPSFSENYDDVSVDELLSHL
The following text describes a protein:
Function:
RNA-binding protein involved in the biogenesis of circular RNAs (circRNAs), which are produced by back-splicing circularization of pre-mRNAs. Acts by binding to both exon-intron boundary and 3'-UTR of pre-mRNAs to promote circRNA biogenesis through dimerization and the association with the spliceosome. Required for spermatogenesis via involvement in circRNA biogenesis. Regulates the pre-mRNA processing of ATP5MC1; preventing its degradation. Also binds the poly(A) tail of mRNAs; controlling poly(A) length in neuronal cells.
Subcellular Localization:
Nucleus speckle.
Sequence:
MRDTERKRQRHRQREKQAPCREPDMRLHHGTPGLRRGPKAGAQLLSHPDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTDPSSLKSSDTNIFDNNVSSNKSSFSRGDERRHEAAVPPLAVASTRPEKRDSRVSTSSQEQKTTNVRQTYDDGAATRLMSTVKPLREPAPSEDVIDIKPEPDDLIDEDLNFVQENPLSQKKPTVTLTYGSSRPSIEIYRPPASRNADSGAHLNRLQFQQQQNSIHAAKQPDIQNSRVYETGRLCEPEVLNSLEDTYSPFFRNNSEKMSIEEENFRKRKLPVVSSVVKVKKFNHDGEEEEEDDDCGSRTGSISSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVSQKQTLPVAPRTRTSQEELLAEMVQGQSRTPRISPPMKEEETKGDNIEKSQGTQQRQLLSRLQIDPVMAETLQISQDYYDMESMVHADTRSFILKKPKLSEEIVVASNQESGMKTADTLRVLSGHLMQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEDMCFEGVKPVNQTAASNKGLRGLLHPQQLQLMSRQLDDPNGSFLNAEMSELSVVQKPEKLLERCKYWPACKNGDECAYHHPVSPCKAFPNCKFAEKCLFVHPNCKYDAKCTKPDCPFTHMSRRIPVLPPKPAIATPAPPSSSQLCRYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTITVPPRHALKWIRPQTSE
The following text describes a protein:
Function:
Involved in rRNA-processing and ribosome biosynthesis.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAITSEKKKNLKSLDKIDIKLLEKTIRALLQHIRSSDKPIEKEKVYIQVNTFQPVEKESLRRPSKVFLPHRIMHVTDACLIVKDSQQTYQDLVEQQGLDEVITKVLSIPRLKLKYKTIREKCELRDSHNLFLVDDRVLKYIPLLMGKVFEQKKIKPFPISVLQKKETLRNQVARCLHSTYLKLSAGTSHTILCGLATQTNEQLLENITTVLKCLLTNFIPKGWSAIDNVAIKTADSASLPIWTSDTNLAAHKRHIVHIQDARPLKKSELRAQKRGSSGEGKGNK
The following text describes a protein:
Function:
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
Sequence:
MSRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFKQEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGKDLILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGKGIRYQGEYVRRKEGKTGK
The following text describes a protein:
Function:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Sequence:
MGNTTSDRVSGERHGAKAARSEGAGGHAPGKEHKIMVGSTDDPNVFSLPDSKLPGDKEFVSWQQDLEDSVKPTQQARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSETSCRDLSSSPPGPYGQEMYTFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI
The following text describes a protein:
Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MFRNQYDTDVTTWSPVGRLFQVEYAMEAVKQGSAAIGLRSKTHVVLACVNKANSELSSHQRKIFKVDDHIGVAIAGLTAVGEFRFSGRSERRSIPITLKYLTTADGRVLSRYMRSECINYGYTYESPLPVGRLVYQLADKAQVCTQRSWKRPYGVGLLVAGLDESGAHLYNNCPSGNYFEYQAFAIGSRSQAAKTYLERKFEKFTESSRDDLVKDALFAIRETLQGEKLTSSVCTIAVVGVGEAFNILDQETVQALINEFEISGEEAPINESVAEQSVGDDQRSAAAEEAAPMDI
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MNHTMDDDQNLAFISQLYPDVYTQILPQEEAVKPPKRRRKEIKRAVATGDGSNCFFRKRKLSDEQVNMLEMSFGDEHKLESERKDRLAAELGLDPRQVAVWFQNRRARWKNKRLEEEYNNLKNSHENVVADKCRLESELLQLKEQLYDAEREIQRLAERVERGSSNSPISSSVSVEANETPFFEDYNVRDDGDDYNLFYPVPENTYIDGLEWANLYI
The following text describes a protein:
Function:
Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters. Involved in induction of the ribosome quality control (RQC) pathway; a pathway that degrades nascent peptide chains during problematic translation. Required to prevent stalled ribosomes from frameshifting.
Sequence:
MSDWDSVTRIGSKNRGGPVVRETVIKGKSALNAAQRQGLVVGTEKKFASGNSAGRASAVEGQHLTKVDRSDDIVKPKTVGLQVADAIKKRRTDEGYKMTQKELATKCNTTVTVIQDFERGTAAPDQKVLSAMERVLNIKLRGSDIGKEKFPKKK
The following text describes a protein:
Function:
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MADKPNMTEITSFDKTKLRKTETQEKNPLPTKETIEQERQGESTP
The following text describes a protein:
Function:
[Isoform Holin]: Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space (Probable). Determines the precise timing of host cell lysis (By similarity). Participates with the endolysin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell (By similarity); [Isoform Antiholin]: Counteracts the aggregation of the holin molecules and thus of pore formation.
Subcellular Localization:
Host cell inner membrane; Multi-pass membrane protein. Note=Classified as a class I holin.
Domain:
Isoform Holin has 3 transmembrane regions whereas isoform Antiholin lacks the first transmembrane region; The C-terminus acts as a cytoplasmic regulatory region.
Sequence:
MKMIAWMQHFLETDETKLIYWLTFLMVCMVVDTVLGVLFAKLNPNIKFSSFKIKTGVLIKVSEMILALLAIPFAVPFPAGLPLLYTVYTALCVSEIYSIFGHLRLVDDKSDFLEILENFFKRTSGKNKEEK
The following text describes a protein:
Function:
Transcription factor that plays a pivotal role in azole adaptive responses by regulating the drug accumulation in the cells. Affects the transcriptional responses to ketoconazole of many genes, including the target gene (erg11), an azole transporter gene (cdr4), a hexose transporter gene (hxt13), a stress response gene (kts-1), two transcription factor genes (named kts-2 and fsd-1/ndt80). Also regulates phospholipid synthesis that is not involved in azole resistance.
Sequence:
MEHHHHHRHMHSPSSQQHEHQQHQQYQQPPQHHQHYEAPQHQQQHQHHHHQQQQQQHPVPVPKQEQADNTSAPVLSALPAYPTLPPIWDSTHSPALSASSSSTMQASASSLSSLPPLVLHPPSNGLQPNKPRSRSPSSNRFQTREPAPLSLFDGSPTTELPPIQLDRKRSSSDHSLPSIASLNVGSSLPTLQPTPTPQPPPKFVWPNSNPLSAYYAESDNDGRGASPQHRHDRRSTSVSLDDPQVMMAISALNELKTDSVSSPPNRNAPLRRGMTDQNQEPEPLLSLITTAHPIIESTVQRSSHLYTKTKNFSPRIRSGLEYVEGSLIPVADTVNNVGRRTGIESGVRWILGKRTKSSSDTRESGQNKRHMTSRPVNGTGGEARFSEAPTADASRRTSVSTIETLPAYDDQRSPAYSETVEQNGQAVDPKSALHAQLGNGRVQVTTSSLKETMKEESLRSLKYVLETLRDVTNTLQQGTNELSSVLDQYDRSTTTRDGEDHVMTNGSAPEEDRTRLVERMTELRKSIYSNIKDVSSVVANYTGAALPENAGNLVRHHLLSLPMVWSQASKTTTSSEQPNTQDPNALVRKAAKVALSFSKEGLHIFSQIMEIIRTATDHAEDWRNKKMNQMTPANGTEQEIRPLIDQPLPQVATINGDIPMR
The following text describes a protein:
Function:
Transcription factor that binds ribosomal protein gene promoters and rDNA locus with TBF1. Necessary for the expression of genes involved in assimilation of inorganic sulfate. Also required for the expression of respiratory genes and glycolytic genes. Does not bind to centromeres and is not necessary for efficient chromosome segregationas as does S.cerevisiae CBF1.
Subcellular Localization:
Nucleus.
Sequence:
MVKSHKRTLEKDEEHQEKKKANKISKDDMEIDAELLTQQASDSAHTDTATAAVAAVNNEQGKELEQTESSTNQTSALDKDDKETKDNLNPREETQSSHQEIDIPKDQLTNQQNLADQHQQYQYHQQLAQTNFKTEPTNSAKPPHGSEEWHRQRRENHKEVERKRRESINTGIRELARLIPTTDTNKAQILQRAVEYIKRLKENENNNIEKWTLEKLLTEQAVSELSASNEKLKHELESAYREIEQLKRGKK
The following text describes a protein:
Function:
Putative GTPase-activating protein.
Subcellular Localization:
Cytoplasm.
Sequence:
MARQLFTPPITNPRFDPNQSIRESYKNTTGGMQFQQNLHEDQNDNERSSCDGDENSTTGERLENNKSPILTKQEIDEALNTVTNLPPELSKLIDIFIDDLKQPKYVRPLSVLQLSSLFQSFYIKFDKASFQHVSSANNNGYYFSGGGSSSFLAAKETLSSGLSGIFGRSRSSSGNSLMRPRRSSSLFSNESISNSTNATQMLSPEEIKKQLKINELNNMKIEKYMELCERDVFKKILIVGTSVSSPNKMKTFKPHQLQTFKVGNLFRNSVEFTEYNKLLNEKILCLSKLSTMNKINLIKFLSLNNGIDPEPKFEEIKDILYEFTYHSISPCEKIKALLKLHEIMTYSQEMSNDDYLSLLIYYIITIVPRDIFLNAEFIRLFRYKKKLVETESFALTNLEAALVFVEGLTKNDFSNELQDKLTVNESKILENSISSRVSLPSKTAIMHKNNGNNGSNLGDIVTPTIQRPDVTRSNSYDGFRTVFDSSLKNIIGKIRSYTPPHPNNTSNNNLHSSNNLNIPRSSSQLSMELSNRDTTEMSRDGSRSTSSSSRSSASLEHGNREFTGDLTVTASINGADKKEFQKSWKKYKGYKFEDLTICELRDLFEIYQKMMQ