lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells.
Subcellular Localization:
Cytoplasm.
Sequence:
MEEFLHRTKSRLDRAKQLEKVHTVIGNKCCDLDSIISTLIYAYYLDKVNSPGILCLPVLNVPRGEFNFYSETRFILEELEIPESFLIFKDEINLHQLNEEGRLLVTLVNFSTLSSDDATLEASVVKFINSEKRTNAAEEFQESCSCLVAKEILEKAPELVTQQLAHLLRGSILFSCLSMEHEKIAKQEEDIICILEEKFPELPPRQDIISSMQETKMHMQGTNIEDILLKDIKELSDGDIKVAISSVCISLEELMSCRNIIGELKLFLDKYGIDILILLASYTTEEQMAVQQIAVHSENPELCNQVCCELEESQNPFLDLEPSDYGCEQFLVYHQENSSVTCEQVSAVIKEAINRRRLGMMPNSRTSSTEAVAGSAPLSQGSSGIMELYGSDLDPQPNPVNFVDSAQDINAQDINAQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVADAAGSHHNFLTGIDNYSRVPEGVIVEEETPPSRTSSDNVELFNFDLLPNTRSESSSHSADYSMADDFFFQSDSSEGQQAQKQQLYRDDIAHCSTHLLNTKVPNISLVDFDDAFMHSPENHEDLCEKTPSASDITEFESSLSCEILGSADVKVPPTPMNSLVESSPLDNGPPTFFPEDVVQKINEIGFSVSDTPYWWNESEHIDANEGPMNADPRSSSNQSVLHRTGPWKEQKSGQDNSKARHEPSFQVACPDLHNENPKENSDNHDKNPRQENKIVPDLWNFNNTLQGVSEPGCGTSDVDKYGDYVKQSEDRLCAIKEDSKTKYFAKRKAKSNIDTDSLENSPEIYVENRYSQEFLVENQFMLQQRSTEDLGVDPKPLLPGHIERNLGMWDLLEEEQDTNIVDHHINWEDPFLSCGPYKCLDFTASYTGKDCVVSPPDTNYSTSESNLSPASEDDMKEPEKSNDQEKHHLNEGHQSSNDLNILNNRGLASNGKHTFSENKNVSYFMKECTNNSEAMPKRSYSGNYLNSDYLDNTSSSSTSSELKKNEPNYKLNNHKLDLSILNTNGSTLLGVDLLGKEEVVCLNFQRANKVQNSYLPLPLHNGSVRNILQPKSQSEINECARNSNTSKEVTSDVLSQCQGQSSLELMNIHDNNDKSGQHLHLLNSRILHDPFYESLSPDRNDTVLIVNPLENSEKCQDICVLQAEEEELGAAGYTNHDNWENDLQDDTESSSLNSLDDLESSDSSYLRSWNLLVKSPVLKDEIRIPGQLSSVHEQDNYDIKSPSIKSKMYNKSVLISPKGKLNDMNGTKISVENDHLTLDEIKIKENVLFNDVDYQKKTDITHCDGEGSVMQDEGSKGKWNKTNLCSYESAGINSNVSPNISKVYMKEELNIYPCNEEDIQSSSSHSGGTSPDLDLSWKRLQEKDYDSTSSVYASESKNNEQCSITQNGSANNEYVNTQVKIQLNTVNKVPMNLDIWNTRICEDSESSSSPEGNETRDHSNSSDEKPLNYFQNVHTSLDIADSNSTTPYTDEESPEIEDIRGRFGFLQDGCVNNVMKDQKEQKGCLTTINGKAEHEEGLLNQDCLQHVQCCPDDRSQPCENVHHDRDYKELFITEKTSPSGADIKDSLSRGSQSTETFDMWYNQNEVYHPEDTNVTTSPQPSHSYHENGANKEKECNNAATCTSLIKFSPHSLCSTTDNYKEDSSENLKCLSATNPIKIQPTDSTPLISLTDKININEFIPESYNDKSADKTEPGVQLQSGMKHELETVTDMSSELTQADLSRDKNLQGTVGAHDPISRHHNMALHRSEDLLQFKCQVEQEDLSNHIQPYGGSEISHSMHFECIPDILDDGSREFSPFYSISPDLWSISEHVYIKTSDYGSPDVLNSCDSNTNVSKTPDLYKQCARAYKDVFVWPDPAHSSKSPSGCAEGSKISAAGESNEMYTQNIHLHKNNDFILQPCIKCTKSVCSCCNLEHVCENYNIEDSQAIATTASSATSLKDIDEDVLSNSSASAKLICIPSTQETEENIQKDVLQTAKIHTEPLIKDHSAVEMINPCLQQGKLPGNSNEENWNIVTSPADGDVGLHHEESDQVWNVDNTTGTSLVLFDLGCDSIKIQTEDPVSSNADEEVHGHFESGPCESVNRSVMTVTNVAFQQTKSNESHSVSSPDTFQSISMTNVNENQAIHRPECHSLYIKGKSSPIVPRRLGSEKKSEEFSEQEHSWSIILSQNEASDSSPEDIFSREETVDTGKGWENTFQQRYSCDKQGGYQIDTGGQAYTDLEESFEMCKVEERDIFAHEVSHAPLHFQNISVHIQLPPQDGELAKYLINKEMTENRSIPDDEGMDIPLDESEIRPEPPNSLDLNGSHTRKIKLTAPNINLSLDHSEGSILSDDNLDTPDELDINVDDLDTPDEADSFDYTGQDDQPAVGKAVQEDFESIQEYTAEEERADNRLWRTVVIGEQEQRIDMKVIEPYKKVISHGGYYGEGANAIIVFAACFLPDSSRPDYNYVMENLFLYVISTLELMVAEDYMVVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILALTRPFISSKFSSKIKYVSTLAELSELIPMEYVHIPETIVKYEESRCFPRNVRLDEDLRESESAKAGCLPNEPEMKTLEAEFEKKTGDNV
The following text describes a protein:
Function:
May regulate flowering time by modulating the photoperiod pathway.
Sequence:
MNMNQVAEYVETDPTGRYGRFAEILGRGAMKTVYKAIDEKLGIEVAWSQVKLKEVLRSSVDLQRLYSEVHLLSTLNHKSIIRFYTSWIDVHNHTLNFITELFTSGTLRQYKNKYLRIDIRAIKSWARQILEGLVYLHEHDPPVIHRDLKCDNIFVNGHLGQVKIGDLGLARMLRDCHSAHSIIGTPEFMAPELYEENYNELIDVYSFGMCFLEMITSEFPYSECNHPAQIYKKVVGGKLPGAFYRVGDIEAQRFIGKCLVSASKRVSAKELLQDPFLASDESWMVYTSGAGNPKPFLNENEMDTLKLEDDELRTEMSIAGKLGAEDNKIDLEVQIAYDNGLANNVFFPFDIMNDTSIDVAKEMVKELEIIDWEPVEIAKMIDGAISSLVSDWKYEEDDETPHDHHRHRTDSFHSSSSHASSSQASLSNYMARGLQDWVQDDLHDETYSQSSSHSGSYSNLNYIAVDEYSSQSPVMSRTHNMTRFCPEESSHLQSGQANAYAASSSTNRSLASDNRTLTRNRSLVDVQRQLLHRSPGEEARKRRLFKTVGDVETVGFQSPYAVSRKPPSSRR
The following text describes a protein:
Function:
Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MKLLVILLFSGLITGYRGNSSHSLPSKLLLVSFDGFRADYLQDYEFPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDASTKKRFSDFDDKDPFWWNEAEPIWVTNQLQENRSSAAAMWPGTDVPIHNTTPSYFMNYSSSVSFEERLNNITMWLMNSNPPVTFATLYWEEPDASGHKYGPEDKENMYRVLKGIDDLIGELVHRLKVLGLWENLNVIITSDHGMTQCSKERLINLDLCIDNSSYTLVDLTPVAALLPKINITEVYNKLKVCDPHMNVYLKEEIPARFHYQHNDRIQPIILVADEGWTIVLNKSLSKLGDHGYDNSLSSMHPFLAAHGPAFHKGYKQSTINSVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCINLPEAIGIVIGALLVLTTLTCLIIIMQNRLSVPRPFSRLQLQEDDDDPLIE
The following text describes a protein:
Function:
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. Plays a role in neutrophil transendothelial migration, probably when associated with CD177. Triggers inflammatory processes in neutrophils by interacting with ADGRG3 upstream of F2RL1/PAR2 activation.
Subcellular Localization:
Cytoplasmic granule. Secreted. Cell membrane; Peripheral membrane protein; Extracellular side. Membrane raft; Peripheral membrane protein; Extracellular side. Note=Localizes predominantly to azurophil granules (primary secretory granules) in neutrophils. Secreted upon neutrophil stimulation by TNF-alpha, lipopolysaccharide (LPS), fMLP and CXCL8/IL8 or during neutrophil transmigration. Following secretion tethered to the cell membrane by CD177.
Sequence:
MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP
The following text describes a protein:
Function:
Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein. Postsynaptic density membrane; Single-pass type I membrane protein.
Sequence:
MLVERFSVSLQVIPPVHPGETVFLPRCHPLPCILDSAHLKPRSHLEGLFLSSPPAQQLSFLRSGLLSNLYLHTHDCPVPLLQWLFQLLTWPPETSLGAFGLLWDLSVDGLFCQSDEDVHLWCPSLQEVKEVFHSLGAHSPALYPQGPFQHRGRELKREVSLSGSEQQDTPQETALDISLSYIYKFLTLCALAQPGAYTDANLLVLIELLCRAGLDMGLRLLPKTDLQQLLLLLLENIQEWPGKLRQLCCALSWVSDHHHNLLALVQFFLDVTPRGRQLRSQLSLVVIARMLGQQETLPLWQEKAQLSSLSQLLSRMRPSSLRQYLGSATSPPCQKQQPKASAELDHKVCYLCHSLLTLAEVVVSCQDITPEQWGELQLLCMQLDRHISTHIRESPQAMHRTKLKDLAVQTYIRWQELLTHCQPQGSWPGAQSRGCAMAPHWAVWLLTVGLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTEPTGLLYVGAREALFAFSEEALELQGVISWEAPAEKKAECIQKGKSNQTECFNFIRFLQPYNTSHLYVCGTYAFQPKCAYIDMLTFTLERGEFEDGKGKCPYDPAKGHTGLLVDGELYSATLNNFLGTEPVILRNMGPHHSMKTEYLAFWLNEPHFVGSAYIPESVGSFTGDDDKVYFFFSERAVEYDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLVCSAPDRQLYFNQLQALHTLQDTSWHNTTFFGVFQARWGDVDLSAVCEYQLEEIQRVFEGPYKEYREQAQKWGRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNTLNFIKKHPLMEEQVGPRWGRPLLVKKDTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQVFDQEPVESLVLSRSKKLLFTGSRSQLVQLPLADCMKYRSCADCVLARDPYCAWSVNTSHCVAVGGHSGALLIQHVTVSDTSGICNFRGTKKVRLTPKNITVVAGTDLVLPCRLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKAAERTLVYPLELPKEPTSPPFRPGPETDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
The following text describes a protein:
Function:
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
Domain:
Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
Sequence:
MTATPADRPDPGVAGDADWAAEARPLLVHADMRLCKRFDQGEPTERLLALRARAVDQLMRNAWTRCIPADAGLSLHAVGGYGRGELFPRSDVDLLVLGETAAQQRHEQALARLFALLWDVGLPISHAVRSPAQCTSAAADQTVLTALIESRPLVADAQARAALAAAIAPQQVWPPRAFFQAKREELHARHQRFGDTADNLEPDIKDGPGGLRDLQTLGWMALRAFGVKDLEALVGLGHVGMDEAAALRREREELARLRYGLHLVANRPEERLRFDYQKTLAERLGFADDPESLGVEKMMQRFYRSAALIRRISDRLLQRFEEQFDGEAVPVQLDAGFSLRRGYLTADADTWPDGDVVQVFALFAQWAAHREVRGLHSLTARALAEVLRDLPAYDVADAIARDRFMALLRGPRAVETLNRMARLGVLGQWIPAFASVSGRMQFDLFHVYTVDQHTLMVLRNIALFAAGRADERFSITHEVWPRLRKPELLLLAGLFHDIAKGRGGDHSELGAVDARAFCLAHRLSEGDTELVTWLVEQHLRMSVTAQKQDISDPEVIHRFATLVGTRERLDYLYLLTCADIAGTSPKLWNAWKDRLLADLYFAARRALREGLEHPPPREERLREARESARTLMQAQGHDDATIDRQFAGMPDENFLRFRPEQLAWQAASLIEVQIGQTLVKARRAVPDNDALEVFVYSPDRDGLFSAIVATLDRKGYGIHRARVLDAPHDAIFDVFEVLPQDSSADGDPQRLAAALRQVLAGDLLKVRPSRRAVPRQLRHFRFAPRVEFSESAGGRRTRISLVAPDRPGLLADVAHVLRMQHLRVHDARIATFGERAEDQFQITDEHDRPLPDAARQALRDALCACLDPT
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as a non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPTRVFVVHMSALPAARLFRRARRAGMMTEDYAWVATDGVGGVVDALGPDDIGAMDGVVSLRPFVRVTERVSNFSARFRARLRREHPSADIYPHDPTVVMLWSYDTAWAIAAAAGVSSPTFQTSQQSAGVTDLDRLRVSATGAALLKAVRETTFRGLAGNFTLVDGQLQPPAYEFVNIVGKSSRAVGFWTPEAGITQTLGAEAAKKGLKKILWPGDSTSVPRGWVVSPNGRKLRVAVPVKHGFKEFVDVAGESTTGGHANVTGYCIEVFDAVMSKMPYPVSYEYVPFPYSSSSYDSLVSLVPRQIADIVVGDVTITASRMGSADFSMPFTDSGWSMVVAVRTETSTSMWIFLRPLTTSLWLASLAFFCFTGFVVWAIEHRINPSSAARRGSSSASSSTSPSPPSSSRTVRARESSSVISTDKGEAGEQPVEVRGDHLGVRRPDPDVELHGEPDVDADSAEAPAGGDRRERAPTDRRLHRVPGGLLHQEFAQETRLPRGQDEELQHGGGVRRRAVQGAGQRRGRRRVRRDPVPEALLVAVLRRLHHVWAGLQDRRLRVRLPDRQPADAGRVTGASDAGGRREDGADRKEVVRRAGSVPEPGRRRPRLLQPQLPELRRSVPHHRRRVQPHAARLPRHLHLPGARRGPARAGGGRLGELVVGAPAARVAAALRPEGPQVRHVQNGGPRLRQGWWEPDSEVGGVRQVWPWRKRVGAGGNRGGSRSNGHEPSQVRHLHPVGDDERRLVPGVRVRDLVRAEDAGGATLCVGGDAKIDALLNVHCREIAPWHA
The following text describes a protein:
Function:
Involved in cellular auxin homeostasis by regulating auxin metabolism. Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.
Subcellular Localization:
Endomembrane system. Membrane; Multi-pass membrane protein.
Sequence:
MLVREIIKCACFAVIKIMCITLMGFAASKLSGFNTQVRSIFSKLIFTYFMPCVVLYQVATAIDTISELKELWILPVASIIHTSLQFFPVLIASYIIRIPKEERSLYSFVLGFANVMYIPMAVIEALTGETDELGENAKSKANQYICAYQISFMVTFFIIGYDYFSLTTREPENKGKNDSQIKEPGEVAIEMEETQPVEKKDEVSKEFEVKQSTKSEEISKDIETPKPSKEEDKNIPKEDETLTKEDENIPKEDETLTKEDENIPKEDKTLNKEGSTNIQTEEMIKIDKTSSKEEDSKVDETISNNKKDMSGESSKINKMKIEIDKFKKKLHKIKKTVCYPFVYVWNKLPSIVRSSIKNFFSPPTICTIIGVILMLLKWVRDPLFIRTDWSIIGRCINYMGSAAVFCALFLLGGSFEKGPFGSSIPFWKIVIGVFVRMVLFPAVSWVCTFFMWKYDILPSNKVFYFVLQMESFAPPAINGLIVVNVCYPKGVKSCSAILFWCYMFAILNIIFGVVLSMKSLEWK
The following text describes a protein:
Function:
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MSWCCCNRLSTSTSSDLWRQFNIPNVGLRQKKRSVSAYYGLKTPPYKLDALEPYMSQRMVEIHWGEHHRGYVESLNKQIENNDIFYGCTMEQLIKLTYNNGNPLPEFSDAAQVWNHDFFWESMQPGGGDMPKLGFLHQIDKDFGSFTNFKDKFIEAALTLFGSGWIWLVLSREEKRLAIIKTSNAVNPLVWNDIPLIGLDLWEHAYYLDYKNDKAKYVNVFMNHLVSWDAALGRMARAQAFVNLGEPKIPVA
The following text describes a protein:
Function:
Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
Subcellular Localization:
Endoplasmic reticulum. Golgi apparatus, cis-Golgi network.
Sequence:
MSQSQPPRHSSMLSASTSGTNIAGTADRQPPPKQVTTVAQQSPGLRIPSNRKTIYDRHLNRSRNAELSRASFAFLFAEMVTYAQRRVTGIQDLERRLNEQGYPLGLRLLDLLFYRSMSSSTSTSLSSSSTSASPPNRPLRILPLLHLIHGPLWRLLFQRPADALEHSVSPETPNEYMITDNDPLVNTYISVPKEMNMLNCAAFVAGIIEGVCDGCGFEAKVTAHNQPTEMWPGRTIFLLRFGESVMEREKVLERAGVK
The following text describes a protein:
Function:
Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival (By similarity). Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes (By similarity). Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways (By similarity). Neurotrophic activity is enhanced by binding to heme (By similarity). Also acts as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity).
Miscellaneous:
MISCELLANEOUS: Non-classical progesterone receptors involved in extranuclear signaling are classified in 2 groups: the class II progestin and adipoQ receptor (PAQR) family (also called mPRs) (PAQR5, PAQR6, PAQR7, PAQR8 and PAQR9) and the b5-like heme/steroid-binding protein family (also called MAPRs) (PGRMC1, PGRMC2, NENF and CYB5D2).
Subcellular Localization:
Secreted, extracellular space. Mitochondrion. Endoplasmic reticulum. Note=Localized to mitochondria and endoplasmic reticulum by PINK1 and PARK7.
Domain:
The cytochrome b5 heme-binding domain was proven to bind heme, although it lacks the conserved iron-binding His residue at position 79.
Sequence:
MAGPAPGRRLVALALIVALAVGLPTAGAGQAPRPAERGPPVRLFTEEELARYGGEEEDQPIYMAVKGVVFDVTSGKEFYGRGAPYNALTGKDSTRGVAKMSLDPADLTHDTTGLTAEELESLDDVFTRVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF
The following text describes a protein:
Function:
Serine/threonine-protein kinase which may play a role in lin-12-mediated cell-fate decisions.
Subcellular Localization:
[Isoform a]: Cytoplasm.
Sequence:
MPLGLFSSGKAQVLCDEKIPGGKKKEPKQLSENKCKGVTLKLDHTRVTIEKQIAEGGFAIVYVASDRKNNKFALKRQFTKDNEKQLEACCREHSFLKQCIGHKNIVEFVDSYTNCLGNGIWECMLLTEYHQKNVLQLMNERISQNQYLTNDEILSIFTDLCEAVSFIHNRPQPIIHRDLKVENVLISSHKPPHYVLCDFGSATTQILSVEKYGVEYVKSEVERNTTMCYRSPEMIDFYSGLEIGLKSDIWALGVLLYRLCFFCVPFEESPLAIQSVNYQFPSVPNIPDEIKVLIYMLLDIDVNRRPSIYQTSVLAFEANHRKPLSEEIQNKKCTDAVPSLKSCIQLMRDGSNPRNKRDSSPRNPEAPPIQSSSKMASLSQQVPSISNISMPSGSGTVETSVAPRLRPKATTVVPNVPSISPVPPVGLPHLRLPSKGSTDETDGSQVRKVPIDFHHRQSFSGEEQLKPAAEADSAGPLSCPLIKPTDLGFTDLDKPALPRDRAQTDGKRRLPHESDIIFQQQHRRNVSDTSQISRSAFKPYSSQQTTSKTSSQVVRSVEDMSQRQNGGSGEWNPFLVAPFSNNSISRKDGQESAFMMDDSHFGMVFDEIRRKEIPAELDSETSSIDSRDPFGAAPFDQLTVSTSSSAQPVSLPPATDEDDERQLLSETDEEEKYEIDEKEEIQTKKDETINEEDSEIDEQRMNDRRRYSYENIDGVGDDASSDSRGKTDRDDSEEEEDDDSRRGGDTSHDEDSQNTVGSEDGEGGSRPLLEDDGLEDDDDHELISSFSSSSTNYPPLFIGTSTPHTQNPITNPFLRDELTPKMIITAPLPTAKNNLDDDWDLGDRWTDRRDTVFERPASEHQNVFAPATLPRQATPLVCRFKPDLPTAAPVSIIPSMSNTSFPEAVRDSDTVPCEPIIGTLISVGAPTDPPPPPLPKKPTEASPTQETTATIPVALGKKEKLLKKEKKKEKKDGKKDKLKLEEYREKGSSEPETDGSEAEIWTNDGATTFSNKKKKKSTFGLRSSHPSIVANDLQFSSPMPPVVKKSSKDKKSSLTGKNASFVNTSFQPEDHDDPTDL
The following text describes a protein:
Function:
Required for meiotic DNA recombination in females. Probably not involved in DNA repair and recombination in somatic cells.
Subcellular Localization:
Nucleus.
Sequence:
MNPTLSRGGAPSRFVRGRGRGGGAYRPYFYFRRNGRVIPAGGNRQPNQGEPGAPDAPSVPPATRQPRGWSRTAGKRGRNAHLDCSFLRPENYAAPEDGLQVQSIAVDNPRAYSGWRLYFLREKYEEGNELATRIMAVEAYYQRNPHTFDFVMIRDRGFFPLCAAGIKSDAQLKEVWPSLSEDIREHPLRTLGTLSLAMHTVVVNHQLDCNDSTTAMVSTPEQYVLPTPRVRKIYARPDDFVPVESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMRQRGTFQPRPYQCKRSECVARDEFVPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMPAEMDVELRHDLVDAVRVGQEVVVTGILKLQELGDDTTTGDTSNQMQPYLKAVSIRDASSIKREFSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGGKGAETEAINVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFAGRNKRVLQAGSLMMASGGGHCTLDDVDKLASKQAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQNINISPSLLREFHLVYILLDKPSERDMSLTAHVRALHAGARKRARIAARYALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDDNDSIMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYARQELNPVLNEDASNAVLRYFLELKGSCNLDEDVSSQIGAGQLLAIIHLSQARARLDLSHVVSPQHVRDVIALLTESITQTSLKEGSSRQGTRGGGGAGGGAGKSAQLRNFLELTKRRSAALGRRIFEFDELKEIGTRAGILTGFSQLVEMANLGGYLLMKGANMYEVVPD
The following text describes a protein:
Function:
Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MDLTMKKILLPAALIIFLSGCASHIKDGPPHFYVNVNKIPNPKPRPLPRSKYGNPSSYTVNGKRYHVLKTARGYQRRGIASWYGTKFHGQLTSTREPYNMLAMTGASPVLPIPCFVRVTNLSNGRSVVVKINDRGPFAPHRILDLSYAAAKKLGYVNRGTALVEVKAIDFTHPHSPTKSVTLAKAASPSHLFIQLGAFRERTHAENLKRELRAYIKKPIFVLRSIYNQLPLYRVQIGPLSNINESNYLHDELKKLGFGEIITMKE
The following text describes a protein:
Function:
Involved in gonadal development.
Subcellular Localization:
Nucleus.
Sequence:
MEIVGCRAEDSSCPFRPPAMLFHGISGGHIQGIMEEMERRSKSEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKIADRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALSPPGTATTLTDLTNPSITVVTAVTSNMDSHESASPSQTTLTNLF
The following text describes a protein:
Function:
Responsible for glycerol-3-phosphate uptake.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLNIFKPAPHIERLDDSKMDAAYKRLRLQVFIGIFIGYAGYYLLRKNFAFAIPYLQEQGFSKTELGLVLAAVSIAYGFSKFIMGMVSDRCNPRYFLATGLFLSAIVNILFVSMPWVTSSVTIMFIFMFINGWFQGMGWPPCGRTMAHWFSISERGTKMSIWNVAHNIGGGILAPLVTLGIAMFVTWKSVFFFPAIIAIIISFLIVLLVRDTPQSCGLPPIEEYRNDYPKHAFKNQEKELTTKEILFQYVLNNKFLWYIAFANVFVYFVRYGVVDWAPTYLTEAKGFSPEDSRWSYFLYEYAGIPGTILCGWISDRFFKSRRAPAGVLFMAGVFIAVLVYWLNPAGNPLVDNIALISIGFLIYGPVMLIGLQAIDLAPKKAAGTAAGLTGFFGYIGGSAFANAIMGFVVDRFNWNGGFIMLISSCILAIVFLALTWNTGKRAEHV
The following text describes a protein:
Function:
Plays a role in transport between endoplasmic reticulum and Golgi.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MRRLNRKKTLSLVKELDAFPKVPESYVETSASGGTVSLIAFTTMALLTIMEFSVYQDTWMKYEYEVDKDFSSKLRINIDITVAMKCQYVGADVLDLAETMVASADGLVYEPAVFDLSPQQKEWQRMLQLIQSRLQEEHSLQDVIFKSAFKSASTALPPREDDSSQSPDACRIHGHLYVNKVAGNFHITVGKAIPHPRGHAHLAALVNHESYNFSHRIDHLSFGELVPAIINPLDGTEKIAIDHNQMFQYFITVVPTKLHTYKISADTHQFSVTERERIINHAAGSHGVSGIFMKYDLSSLMVTVTEEHMPFWQFFVRLCGIVGGIFSTTGMLHGIGKFIVEIICCRFRLGSYKPVNSVPFEDGHTDNHLPLLENNTH
The following text describes a protein:
Function:
Plays a role in processing of mitochondrial RNA precursors and in stabilization of a subset of mature mitochondrial RNA species, such as MT-CO1, MT-CO2, MT-CYB, MT-CO3, MT-ND3, MT-ND5 and MT-ATP8/6. May play a role in cell cycle progression.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MASRLMQRCICLLATHQVSPLTVISRVRLAKVPCSMMTTTHGSTVSTLDNILDKEPVFTPYPWPQKVDQQIEKARSPEEILELLDGRHKLHHNHTAIMVIKLSRLLADKHQDRDLIIKDNRVQKLFHSVDKQVSSIWHGTLMSLLRSLYTLQLRENSRCLRSVEQEVRWRLRRVKYKNLVFLAETSIPYMQEQASKELLTELLMYLERRWTEIDDCRTVVTLMTKVGHLSEPLMGRLEDKHMLNKADSFTPLQLSNMILAFARLNFHPEQEEQFFSLVHKKLEPELANLSPILQVDVVWSLCVLQQVQEAQLQGVLCQEFHKQFLDSKFPQNQNICQKLVHINATAQLEHPKYIGPYLPLALPTGLPPPNLHRKMTPMQKDLQDIMKGWLGSEDKVRFGETTQYGWELDAELVLDVENQPLPMKNFIAPHLAQPTGTQPLPPGAKRLAFLRWEFPNFNSRSKDLLGRFVMARRHLQAAGLLVVDVPYYEWLELKSEWQKGAYLKDKMGKTVAEDLAK
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex (PIC) with RNA polymerase II and the general transcription factors. The essential med11/22 heterodimer specifically functions in promoting stable PIC formation (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTNSDDDLFSEKSTSSDTQQVQNILELEAKIPDILSSAGKCIEAIQLNNSLEDFRKYSKEFLETVEFISTGLRRQALELEKAEVPVVSLQPKKRYASTPLSNLIFDQSSKLM
The following text describes a protein:
Function:
Probable transcription factor; required for proper organization of muscle myofilaments and for their recruitment to the M line.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MENRTPMQHHSGYEIVKSEPPSTPKTLIKSSYMENTPEMVFGSFPIHSGFCTQVVTHTDPMNNNNQPKTNANGRALAADRKRPYPCNLCSSKFGSKMELEEHQNSHTGQKPFECDTCNARFNRRSTLWNHKRIHSDAKPFVCTVCQMTFKWKNSLKCHKDMHQRKNETSAHLDNDLRQLTYATAAKRKLQMEQEENGGLPASSSASSVISHPLITTTSGNKKRSKAAKAKQTPSSLATTLSQVHLGAVQPLHASALVPPSDHQIDLDTTSLDSLMQSQNQNFLMQLYGYSDDGRHNGGMLSLDDTMLSNLSDSKSDSGSSSGGLSIQLPMQTINMLNFRNLGTQQLPPVHQLASSLPSVSSGMDYVNVNQHDSHYIVSQPDMMLGNQPLYHNGSFANIEKSNPHNNQFTIDSCVLLPSSRQDYPFDYTMVNQQYPMQEQVHDQTVGVSVVQQHYAEQAHAHGKTVPHEQW
The following text describes a protein:
Function:
Required for Tn7 transposition. Forms the transposase, together with TnsB. TnsA executes the 5'-DNA strand breakage reaction. TnsABC and TnsD promote high-frequency insertion of Tn7 into a specific target site known as att-Tn7 whereas TnsABC and TnsE promote low-frequency insertion into many different sites.
Sequence:
MAKANSSFSEVQIARRIKEGRGQGHGKDYIPWLTVQEVPSSGRSHRIYSHKTGRVHHLLSDLELAVFLSLEWESSVLDIREQFPLLPSDTRQIAIDSGIKHPVIRGVDQVMSTDFLVDCKDGPFEQFAIQVKPAAALQDERTLEKLELERRYWQQKQIPWFIFTDKEINPVVKENIEWLYSVKTEEVSAELLAQLSPLAHILQEKGDENIINVCKQVDIAYDLELGKTLSEIRALTANGFIKFNIYKSFRANKCADLCISQVVNMEELRYVAN
The following text describes a protein:
Function:
Nucleotidyltransferase that catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs, which is necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded. The structural flexibility of RNA controls the choice between CCA versus CCACCA addition: following the first CCA addition cycle, nucleotide-binding to the active site triggers a clockwise screw motion, producing torque on the RNA. This ejects stable RNAs, whereas unstable RNAs are refolded while bound to the enzyme and subjected to a second CCA catalytic cycle.
Sequence:
MKRPVSNSIVLTTTEEKIRNVLVGYCDYYNKTNNDSLELRITGGWVRDKLLGNESHDIDIAVNHLTGEEFVNGLHDYLRQHEPELSMNHVHTIKMNPEKSKHLETCTTKLFGVDIDFVNLRSEEYTHDSRVPSIEFGTPEQDAVRRDATLNALFYNLNQGEIEDYTKRGLSDLQNGILKTPLAPIKTFLDDPLRIIRLIRFASKFNFVVESETLNAMKEEHNKSALSTKISKERIEIELRKILTSNNPGYGLQLINYVDLASSIFYVPELAKEFDNESLEEARSQLACHMEIASLIYPNFKQTINNSTEKFKNEFAALMTNDDYKNVFWLSVILHPYTNVKSCKPNRDIFNQYLRLGLTSKKSDIAKVSAINMNSAELSRFFSAPELVKRSDIGLYLRKFSEFASLNLIVNALLDCVRKVDQFTQLPKELPVPFPEVGEKILGDENINKVISEIVSRYENLFVQIENWDLTNVHLVKPLIDGTTLSKSLGMKPGPWLRPTIEEILVWQLDNPQSSVDECFEFVKSIIPKYK
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MNSQVQADQNSAINQGMELRNTASSGKLQMSGKGCDSYVRLLSRNEPAEKELERSDDECEDSKSEESGDAPWHYKQPFKHRKRMAYTRIQLLELEKEFHFTRYLTKERRTEMARMLDLTERQVKIWFQNRRMKWKKDNKPVIPTSRGMRKGCTR