lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Bifunctional heme-containing enzyme that oxidizes linoleic acid to (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate (within the N-terminal heme peroxidase domain), which is subsequently isomerized to (5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate (within the C-terminal P450 heme thiolate domain). Oxidized unsaturated fatty acids, so-called oxylipins, derived from endogenous fatty acids, influence the development of the asexual conidiophores and sexual cleistothecia and regulate the secondary metabolism. These substances were collectively named psi factors and are primarily a mixture of hydroxylated oleic, linoleic and alpha-linolenic acids. They are termed psi-beta, psi-alpha, and psi-gamma, respectively (By similarity).
Sequence:
MGEDKETNILAGLGNTISQVENVVAASLRPLPTATGDGTYVAESTQTGLAKDLSHVDLKDVRTLAEVVKSAATGEPVDDKQYIMERVIQLAAGLPSTSRNAAELTKSFLNMLWNDLEHPPVSYLGADSMHRKADGSGNNRFWPQLGAAGSAYARSVRPKTMQSPSLPDPETIFDCLLRRKEYREHPNKISSVLFYLASIIIHDLFQTDPKDNSVSKTSSYLDLSPLYGNNQDEQNLVRTFKDGKLKPDCFATKRVLGFPPGVGVLLIMFNRFHNYVVDQLAAINECGRFTKPDESNVDEYAKYDNNLFQTGRLVTCGLYANIILKDYVRTILNINRTDSTWSLDPRMEMKDGLLGEAAAMATGNQVSAEFNVVYRWHACISKRDEKWTEDFHREIMPGVDPSTLSMQDFVAGLGRWQAGLPQEPLERPFSGLQRKPDGAFNDDDLVNLFEKSVEDCAGAFGASHVPAIFKSVEALGIMQARRWNLGTLNEFRQYFNLAPHKTFEDINSDPYIADQLKRLYDHPDLVEIYPGVVVEEAKDSMVPGSGLCTNFTISRAILSDAVALVRGDRFYTVDYTPKHLTNWAYNEIQPNNAVDQGQVFYKLVLRAFPNHFDGNSIYAHFPLVVPSENEKILKSLGVAEKYSWEKPSRISHPIFISSHAACMSILENQETFKVTWGRKIEFLMQRDKHQYGKDFMLSGDRPPNAASRKMMGSALYRDEWEAEVKNFYEQTTLKLLHKNSYKLAGVNQVDIVRDVANLAQVHFCSSVFSLPLKTDSNPRGIFAESELYKIMAAVFTAIFYDADIGKSFELNQAARTVTQQLGQLTMANVEIIAKTGLIANLVNRLHRRDVLSEYGIHMIQRLLDSGLPATEIVWTHILPTAGGMVANQAQLFSQCLDYYLSEEGSGHLPEINRLAKENTPEADELLTRYFMEGARLRSSVALPRVAAQPTVVEDNGEKLTIKAGQVVMCNLVSACMDPTAFPDPEKVKLDRDMNLYAHFGFGPHKCLGLDLCKTGLSTMLKVLGRLDNLRRAPGAQGQLKKLSGPGGIAKYMNEDQSGFTPFPSTMKIQWDGELPQLKEDF
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MAPSLPPNNTSTPATPKRISVFSANYNPASQVGSSTNINNNNNRYVSPSKKRQLQFGTPPVTRTPLRVAALPSIPATPRTDILKQLPEPPQIPEGRVGYDPELRSILSHHEESLSKLIDRYSRLKLDLSHQLNLELADSEHQRTNAKCELAVVQKQLAETVESNDKLKNELTAARNRLNKLTDDRRGMELKLGELNDAFELCREKFSSLDNKKKLEKHHLGLVVQETKKELDFLEEITGLSILIVAPDRLKFNFKLIDMNAYDRVFSIELDLSDFDYKILSIDPPCSKLFNSPT
The following text describes a protein:
Function:
Regulates the expression of the mymA operon (Rv3083-Rv3089).
Sequence:
MELGSLIRATNLWGYTDLMRELGADPLPFLRRFDIPPGIEHQEDAFMSLAGFVRMLEASAAELDCPDFGLRLARWQGLGILGPVAVIARNAATLFGGLEAIGRYLYVHSPALTLTVSSTTARSNVRFGYEVTEPGIPYPLQGYELSMANAARMIRLLGGPQARARVFSFRHAQLGTDAAYREALGCTVRFGRTWCGFEVDHRLAGRPIDHADPETKRIATKYLESQYLPSDATLSERVVGLARRLLPTGQCSAEAIADQLDMHPRTLQRRLAAEGLRCHDLIERERRAQAARYLAQPGLYLSQIAVLLGYSEQSALNRSCRRWFGMTPRQYRAYGGVSGR
The following text describes a protein:
Function:
Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation. PTI1 is required for 3'-end formation of snoRNAs.
Miscellaneous:
MISCELLANEOUS: Present with 937 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MTDPRRRTGRHFLTPENLSSTLQITNLPPEWNQDIITSVVAGSGPVIDIKAKNDPRTGKLTGVLFDYLTSKDCKRAWEILNRIENFPVKIEQIIPPNYKDHLRETANKNSQKQVLQLNRDSYPFEAGLELPFEMVTEVPIPRRPPPPQAANNTNSVSNNTNIQFPDILSKASKHLPSFQDGSIIAPDKISQNLSKIPPLQLIEIISNLKILSNQENIQKSQLESFLDTNSDITISVTQALLEMGFIDYSVVTKVLKSQVGEAPSLLSSNNTSNSNTPVSVIRNNTPLHVPSNEVSNNPNNMPLNVAMPMPMSTPPFIPLPLQQQPFGFAPPGPFMPPAQGPSMGQPVLANQLGQVQQQNISSTEGPSNANKANDSGTINMAKLQLLPENQQDMIKQVLTLTPAQIQSLPSDQQLMVENFRKEYII
The following text describes a protein:
Function:
Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MVLILDNDLKPLYFTLAIISASFLVKRAYQSTNIYDFFNIKKKCNPFPQSQSELVDLLHYQKRMVLNKTIVETLKFVDRKLFLENKNVENPYYDEPKPIGYNATISAPHMHALMLDLLADRIPMSNGVALDIGSGSGYVTACLGHLMGCTGRVIGVEHIPELIERSIESIKRLDSTLLDRIQFLVGDGIKGWKQLKYDIIYLGAAIESLQVARELIDQLKNGGRIVMPVGKSNDFHELMVVDKNEDGIVSIKSLGVVRFVPLTSKENQLNPKNKPNATKVTNINGEKTLIRCEIIPAPDSNSNNNIKEFENLINKK
The following text describes a protein:
Function:
Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Subcellular Localization:
Cytoplasm, myofibril, sarcomere, Z line. Note=Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle.
Sequence:
MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKMRQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNPDNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELPDYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTEPTDDTTVPESEDL
The following text describes a protein:
Function:
Required for sorting and processing of soluble vacuolar proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MSDIELHESAIPKELDSPVTTIALYNNHLYFGTEGGDVFLYNFSNFQLNESPELVKKISLVSKSRVNRILAMPFLGAVFIHHGSFAEVYKEDDLTQLYPSISFKGLVEFCHPGQRIDEKSTYLIVTNTHLKLISFQKDGIILVKNELKYPNIQTARVNGHIVCLVTENSFELLDILTFDTTPLFPIIKYDSENNGLMYKPMIVLHSNEFLLITGSPKDAIGLFVDSQGNVTRSTLTFSFYPKHVFSTSHYVFAISSSSLQIIDINTLSLVKSINLKDDESFSFISRLTSVHFCDRQIFSKFSAVNTASTSKTSDTIERASFSKPSFIFLTNKSWGFGAEAHFMNKLEFSITIGDIEAPLRRVSKRLRNPKKYGITNDVAYLQSAYLEQISALQYWKQGQYENSLSLLETSKIDPRVVISLYPDLYHSELSYIAFQGVISFRKSILSVDDTVANVLKSNELFRDTDQYTQRQMIEITKENAYIMLMRYLKNYKKNTSISEYLLSSQRDVMLAVEHSLLLLYLNMDDLAAGTKNAKELLESGLTGVEDIKDVLIQKKEYYLLSVLLATVRDHDGVLQTWKKLITGDYEDRRFNDGLIKIREYLVNDIEPSTFWEFTTWLCKHDATEGTRVLLDKTVSGSISAEDVLEHLDSSQDDVLIDYLVKSNSVTHRALLLKLCVNKLLGSLLDHNDFKNRLETAIETFRELPCMEKPTYAQYLEQLWGDMSDFSTHLSFYYLCSINLMENVEEESIDKIKDILFDIHVDNLYLFPQLEHSFYKRKKNYEKALSVLVTNIHDYKGGEAYCLQIDDVYPQCWCNLLEKCISTGDGCSDFIKELLYRRPFSYTLSYVCEQIPDHWNLNLLADFLCILQKRNAERLNESQTRLTLEKSLSQNLEELFMAINRRNVALGKNEI
The following text describes a protein:
Function:
Hydrolyzes the gluconolactone formed by glucose-fructose oxidoreductase, and that formed in aerobic conditions by the glucose dehydrogenase present.
Subcellular Localization:
Periplasm.
Sequence:
MTTGRMSRRECLSAAVMVPIAAMTATATITGSAQAAKNNMNGSTIGKITKFSPRLDAILDVSTPIEVIASDIQWSEGPVWVKNGNFLLFSDPPANIMRKWTPDAGVSIFLKPSGHAEPIPAGQFREPGSNGMKVGPDGKIWVADSGTRAIMKVDPVTRQRSVVVDNYKGKRFNSPNDLFFSKSGAVYFTDPPYGLTNLDESDIKEMNYNGVFRLSPDGRLDLIEAGLSRPNGLALSPDETKLYVSNSDRASPNIWVYSLDSNGLPTSRTLLRNFRKEYFDQGLAGLPDGMNIDKQGNLFASAPGGIYIFAPDGECLGLISGNPGQPLSNCCFGEKGQTLFISASHNVVRVRTKTFG
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MQMKLDNTSHPQLDPTNCMASSKAWWHGVRSNVVLSDMLEESTKNLLTSNYMDDGCGGKSGKSRAANHQFGEGTDAYKEMQFTALPQSDGKYGEEHQQQHLQHSVSFMPPPMVEYLVPPTQLEHVGPSLVHSCYLGAYPTRMVLPLEMTEEPVYVNAKQYHGILRRRQSRAKAELEKKLIKVRKPYLHESRHLHAMRRARGCGGRFINTKKLDNSAAKTTLDKANNFIDTVLKPSTNSSSAHSSKRSDSSAGNVVIEPDHLHKQISQRTYNGGDGTACSQYFLGFQLSSCHSQSDRMVEERDSNMKELW
The following text describes a protein:
Function:
Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Subcellular Localization:
Cytoplasm.
Sequence:
MELILGSQSSTRANLLKEHGIKFEQKALYFDEESLKTTDPREFVYLACKGKLEKAKELLANNCAIVVADSVVSVGNRMQRKAKNKQEALEFLKRQNGHEIEVLTCSALISPVLEWLDLSVFRARLKAFDPSEIEKYLESGLWQESAGCVRLEDFHKPYIKSSSENLSVGLGLNVEGLLGALKLGAKLSSL
The following text describes a protein:
Function:
Phosphorylates SCD5.
Miscellaneous:
MISCELLANEOUS: Present with 3000 molecules/cell in log phase SD medium.
Sequence:
MSITNGTSRSVSAMGHPAVERYTPGHIVCVGTHKVEVVNYLAEGGFAQIYVVKFLEYLNEFDNTASVPLKIGDVACLKRVLVQDENGLNEMRNEVEVMKKLKGAPNIVQYFDSNASRRRDGVQGFEVLLLMELCPNKSLLDYMNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTGQFAILHSKYEFPVNKYSSKLINLIIIMLAENPNLRPNIYQVLYHLCEILNVEVPIEDKYAEGAYNFSKYTQFQNKLQNVQLQMYQLQQKKIMQNNKLSDSEENLLNDMFLSSFEISSKLPMNASDGHAAVSRIPSQNVGQELEEEKESQSDQRKSTLSEDKSSRTTSNANSSGTANNPQEINTIQSPGIEDKSIFENKTPGELYYPSVSELDTYLDKELVKQSSDPTISEQSPRLNTQSLPQRQKSTSSYSSGGRSMKSTSYGAATIGSDEALANEKTAGINKMKQHKSNNPFPKMNVAYHSTNELSNDASNFFLEEQQQGQRYQQAQNQTGTQGNTFPDESQYQSRVEQQQQQQDQPKGPANYSQRNFYTGRDRSNKPMQLGGTIAGDSGNRRVNFQNISQNYATNSQSGYLPSQNSPAIPMVRPVISMNQQQAQQIQAQQLQAQQMQAKQQMQAKQQMQVQQQLQVQQQMQIQNANNNGTYVSDRTNHTTEDMRNAQGGEPPILAGNSANEPMHSSSKNEALLIELSPLKEDAGKQSFQDTNEPQTGGIEDAGGSGTIKGSNNNRNGVLNLSLNEMDLSRDDTGAAVSSFSSSSSSASIQQAKLSGRKGSSKRNNYSTDELGDSMVSSESIDIDLDDARRGKTAERRPLHNERGHKDQARSSDASKSNQFKSKDFSSVSTRQPRQSLDLNFQEVNLSSPTLTQEHRNKNDSPAPNSHHSYRVSPHASTAITENKRHSTGHELSTRSNGKHETHRTGSKQRHDLERYRHSKDKDSNSSITISTSTPSEMRKSFARARQSLDLERVRREAMASSASSSGGSNGKRRSFFSVFRSEK
The following text describes a protein:
Function:
Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine (By similarity).
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Sequence:
MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADPFRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSALANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDAGPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGASGDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYHLTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDTAARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGIASAVTGMMHGAS
The following text describes a protein:
Function:
Probable E3 ubiquitin-protein ligase that functions downstream of HAL3 and is required for HAL3-regulated plant growth. Activation of HIP1 by HAL3 may lead to the degradation of cell cycle suppressors, resulting in enhancement of cell division and plant growth.
Domain:
The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.
Sequence:
MQGQKNSVEQLADVFGFDHASSSGNPVMDQQGYWNNILGSVESHNLQGYQVNRSDGTIPYGNGVHQNGTFLGFWESGEASASGSSLHFGGSNEIKAEQRNIGGGLRIGERRLVAERNLSLDNVDIGLNINGNDLSGENSNVNGASQGSELHGGCSHTGSNGQASELRLHPYRTFILGADQPEPFNSLNGSENPLGDFSLMPEGIDQRPGSSLDGRRLACKRKNIEGVNGQCSAGASTSFSHRNDSIFHNIASSSHNPSPSTNLPSPNCLLVPSTLDEQLPRYGATTAGLSSSSYDPSGGNNNSGGSQRSFRPRTSLAQHIGPYGVWPSSSTIRHSNSWNHQPPPFQSSFDEPPEVIPVVSSLNFQYQHPMNVVPGIPQMSHRFTGPGASSSRTGNLENRIIGSEEFSARNVVATSFPDAVPPAALDMRHLIPEPSSWNVDGRATTIPGNVPSSSRANTNSMVNPPAGSPFIAHQNLHRRNPRNLSEEISRLSGALRGHQHPRLRSGFLLERQGDGVWGVPLSTRSREGRRLIEIRNALEMIHRGENVRFESIFYGGVDIHDRHRDMRLDIDNMSYEELLALEERIGNVSTGLSEEEVTKLLKQRKFSSWRLEASVEEEPCCICQEEYVDGDDLGTLDCGHDFHVGCVRQWLVVKNTCPICKNTALKS
The following text describes a protein:
Function:
Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules. Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle. The DASH complex mediates bipolar kinetochore-microtubule attachments and facilitates the formation of additional interactions between outer kinetochore components and spindle microtubules. During chromosome movement along the microtubule, it is required both for the sliding of kinetochores along the lateral side of the microtubule and also for microtubule end-on pulling on the kinetochore. Modulates cytoplasmic microtubule dynamics by tracking the plus-end of shortening microtubules and slowing their depolymerization.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton. Note=Associates with the mitotic spindle and the kinetochore (By similarity). In the cytoskeleton, localizes to cortical microtubules (Probable).
Sequence:
MTSELQQELQILRSFNYTIEKLTDGLSASKEKIKSFETSINNSNRLIQLWSSVLSQTEHTQNLILNSDWKGLSFDNEELERLQHQKMLQIQAEEQRKIELQQEQERLEQERRQKEEAIALQKQQQQRLLRSKDPKVRPARRAASSYVPSRPSHVPRSSSMNVRSRVSMATTSNPNSLRTPSSSFASHRQSAIPKSATSSAPTIPTSNLPSVASSIPNNGLNSSNRKSIISKTSSRLRPPSRVSNVPSVPQHPSTRSRTSTRETTQPPFTTNPSNRSKRTTLR
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MSLGQAGQQQRALTQSKDTQLKSYKRRLKEDVSSILDNFTEVLKLAKVEDETQVARQAQGEQDQTEMQVRAGNIVRAGESLISLVADIKQFLILNDFPLANENIEKRARFLGNVQNNVDSKIVQLRDELSNDLYEIEEEYYSSRYK
The following text describes a protein:
Function:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
Subcellular Localization:
Nucleus.
Sequence:
MVEIVFEQASFFKKIIDSLKGLVEDISFKCTSDGMDLQAMDISHVSLISISLPADIFNTYNCSEEMNLAFNVDVLNKVLKSASTDDYLKISTEKPNEDITIQLSTQSEDKNTRFNLKPVDINGDAVSIPEHIYKAKLSLSSNAFNQLIRSLSEVNDSVAVRCTEGSISFSVSDILLNATTTFNAGVTNEKAEEEIEVDVTEGCKVAYALRYLKAISAASALSTRVNLSFSPHFPLLVEYSLQEGGYVRFYLAPKVDEEASEDEV
The following text describes a protein:
Function:
Probable acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by acetylating the cohesin complex component SMC3 (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MKTYRAKRKYLSESEDDVFSSSPTQSPETSPLQPPNESRLNIKAAQAVSPCQKRAKVVKKPAKTKAPVQMTLSLGQTTSTTCKTCGMTYQVAYGPDISAHKSFHSTALNGPKWKPSVSAVVVDKSKTYTVYKSRLLSHPCVSQFLKLVNSELNAPEPILSSQAAVYVYVVDQRAVGCVLVDRITKCRHVDIQTGTLGLKEYPAVMGVSRMYVSQLFRRTGIVTKLLDLAKSDFIYGMELEKNQVAFTQPSEGGLKVAENWAGTVRVYREGE
The following text describes a protein:
Function:
Involved in mitochondrial maintenance during adipogenesis. May be acting by playing a role in the maintenance of normal mitochondrial function.
Subcellular Localization:
Cytoplasm. Mitochondrion.
Domain:
All members of the FAM83 family of proteins share a conserved N-terminal DUF1669 (domain of unknown function 1669) domain of about 300 amino acids. This domain mediates the interaction with casein kinase 1 (CK1) isoforms. Therefore, it has been proposed to rename DUF1669 the polypeptide anchor of CK1 domain.
Sequence:
MSRSRHVGKIRKRLEDVKNQWTRPARADFSDNESARLATDALLDGGPEAYWRALSQEGEVDFLSSAEAQYIQAQAKEPPDAPDSAGGAESGPRGLDSCSLQSGTYFPVASEGSEPALLHTWTLAEKPYLKEKSSATIYFQMDKHNNIRDLVRRCISRASQVLAILMDVFTDVEILCDILEAANKRGVFVCVLLDQGGVKLFQEMCDKVQISDIHLKNISIRSVEGEVYCAKSGRKFAGQIQEKFIISDWRFVLSGSYSFSWLCGHVHRNILSKFTGQAVELFDEEFRRLYASSKPLMGLKSPRLVAPFQPNKGPEAPNGRLSGTSDSASDRTSSNPFSSLSTGSNAHNQSLSTSSGPSSPLAPIPPTVPRLQPYHSTRRAVAPQPLLVPMRPHEGAPAPYSSLMAYRPTRLQLQQLGLVPRVTHPWRPFLQALPHF
The following text describes a protein:
Function:
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKKFFIKTFGCQMNFNDSERIRGLLKTIGYEQTDNWEEADLIILNTCTIREKPDQKVLSHLGEYKKIKEKNPKALIAVAGCLAQRTGWELVKKAPVIDIMFSSFNMHQLPELINQAQAGYKAIAILDELPQDEDKIWEYPVERDNKYCAYVTIIKGCDKNCTYCVVPRTRGKERSRALHSILDEVKRLVDDGVREIHLLGQNVTAWGKDFEKPIPFSELLYQVSKIDGVERIRFTTGHPRDLTDDIIEAMADIPQVCNALHLPFQAGSNRILALMDRGYTKEEYLEKIEKLKEKVKDIAMSTDVIVGFPTETEEDFEHTLDVLKKVRFEQVFSFKFSPRPGTPAAEMEGQIPDDVKTERMRRLLELQKSILSEIAKKYEGTVQEVLVEEEKNGELIGRTTTNKWASFKGDPSLLGKIVKIKVIKSSPFSLEGELLEVIK
The following text describes a protein:
Function:
Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
Subcellular Localization:
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Sequence:
MSDCSPLPPDITSLETSNDPSHTQSYTELALPTASTFVSTEDSHDARLVAMSALSLLEEDARPSCRDGYQRKHGNQGPNTSLWKTHKKHFFILSASGKPIYTRYGDETKLASFMGVIQAIISYYADEDDSIRSVCAGGHLFVFHVRGPLYLVAVSSTGESEYQLRKQLDMLFDQITLTLTALQLDRIFKQRVNYDLRNLIWGTEIFMDTLCKSFQRDSSIFLESMQCTRIPSRLRDRLTQALIDAAPPKDLLFGLLFAKDRLVTLLRPRNYTLHPKDIYLLVNMIMSSSTFRTVQSWTPVCLPHFNNRGFLHTYVCFITSDLCLALMSTDNSAFFSQSEYKQRIVHAFNSNGIIPALDAAIHVRDFSVFELGISELRHFIIKSRTMGQFVEPQPIAPYTRSQDRKRLQRLYQYALELGSLRPTISNVSCFSTHHETVVYQATSTMEIYAAFGPIVKKDIVVSALVELKKWAKRNDETLFMKSSPLLF
The following text describes a protein:
Function:
DNA-binding protein which modulates activity of several transcription factors (By similarity). Plays a role in the modulation of endoplasmic reticulum (ER) homeostasis during chemical and pathogen stress, including exposure to the Gram-negative bacterium P.aeruginosa.
Subcellular Localization:
Nucleus.
Sequence:
MSDDPAFLALGTEVSAKFKGAYCEAKIQKVDRSLKVKVSLKESPFGQMIVQDNDLPNAKFEINELTDVVFQRKFIRCQIQSIKDQSKYHVVFNDGDEKELRRTQLVLKGGKHFAADGNLDSMPLTNPESFSTPVIRGAAKRGAQKIRNAISEASGSRGGAVLLHNDDDENDEEDQEDGENEEDADDDDDDTEEQQQPRERRRAAAISAIGVLKKAIEDTQSEESSADSSEERERARSRRKRKDEASSAVTSDEEDQEDLATTDSENPVINGASSAAALSKTLQRKLEKQAMKREKQRLKEEEREEKLRLKEENREKKRREKARIMELKRLEKVYRTSNARIQENHEKSMTQIISHRSVRYFARFSDLKHRRKKKKLYLHEHRQKVNSRIRNVKLYFAWRFVAHKARLSYFARYALQWWRTSEDQAYSLIRTEKLLRSQRRRDWVGSWLEGLEREKIRFVVIHESYTQARRILKYIERGTEKRTFAERCDIEYEDIESSTVSSHFRDQEWFPAVLFPQVFSDENGSEGRQRIVRHMGNGQLVQVWEDDLVPFDWLPEYSFADVTAMTEKKPVEMRRKFKLAWRFATDYAQNRLDARSIRSILEWKFIRPSSRRLKITPIPVQAPSPNRCGEDHDDLVSTPNESDYDSDATIKNVDAETKDLFVAMLVQFHDAHNSVIDTNPTIQGHEVDLYYLYELAKKTGGPKKVYAANLWSDYAKKLVPAATDAEEELKTIFKNFLESYLAINTKLSWPMESLQPRTERKVVLPGQYSESRKKRTQAIMSQVQTPPTAPGSSKKGRVGSGGTRGRKRKVSSESVQLKKRNRKSSSRATTASPGPSEDRFSFQRPQDSDDVTDVPDDMTDHEDLLPEAATRKKYERKSQTPGRRSLSSRRDDTTPVSSMAAAPPKKGRPRKNTTVTTPVLSVPKSEGRGPRKEDTTTKFVRANVLSHILSGQKLRAFYGDEWFRANAIEDATDCTDEIMDIMLAHQDFFTPDTPRLSPSAIQDLDKVLKKIRAKTHYTGWNQRYDEFMKLEKLMVTVEDQMIARGRFRHLPRGRELKAETLALVEKHFRADDEDDGVPKTLAFYLKIAQEALSLSEKRAVADDDESSDSDTDFEQKPDTSAAAAVNGGKSESEEEEEEKTVVMGGDEEAEEEVKSEDVLVESVDQESPPTTSQGTTTPETAATGGLESESDEPEYPPVPEELVPPPPVLLENFPSTDRFSSGGSSNYPTLSRQGSINSMASPMFSPNSDLSLSGPLTLPRSGPLTMANIRQSPTPDEVVGSLRKRLSQTSESSESSELPPPPSAASKSKRIRRASERSIDSASEHHRMMRSPRILTTQHSSGALIFDISTTQPTDTSGPIEALSVRKPGRRKTVFAASPTLLTSGPLTLSSSAPPPPPASPAPPQHAQKTLGRPRKTPSTSSRKPEEEDEAEQIPTTVVGVTEEASVADSSAKEDLTSEDGSATPQDEKDDSESTTTTDTITPKSIRGGKRRRGGGRFGGSYPVKPAKPGRKPKDPHAEEGADEKDPEDQTPTTMTTSTPTRADSFQTQKNRMAKLMEGKPHDYSFLDLPDFDKIIEEAPKEDINILMEERTYELREIFAQCKADLSALEKRYRQQNEAKRKAEFAAKTASSAAAAQASSSTCSTPRP
The following text describes a protein:
Function:
Involved in embryonic morphogenesis. Plays a role in the organization of apical filamentous actin in epithelial cells of the developing embryo. May play a role in let-60-mediated vulval development. May induce nuclear condensation. Positively regulates the oxidative stress response, and this may be in association with the small GTPase rab-39. Not required for muscle integrity.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MLRSVVNNNDKAKESEQSVRVATDDPTYQSYAFQPSTSSSNISWFGGLRTKLSQLSLFPDWMSQLGIKSDDEKMETSSTSSPQSEQSIGEYDESTLVFRPVQLDHFGGAGQEDDGEQVDIWDFGATFLADLDSNHVWNDTIERQHFGPLKDLITTGGGANKINNHSFKTHSLLHPTWCDKCGDFIWGILKEALKCEHCNYTCHARCRDLVTLDCRSPGSSLASSTEFDSIYPQLDGTLGTIPKGLILPPAMSSSTGSDKENGNGNSAGISAENPIFSVKNSFTLPKSFSPVDSLRTKEPSAPPESRYATLRVVERYVKEDTPFEWTDEYKEMDLERKIHSYNSLAKGMEITLHEDGVNFGGHIHVNMNLSRPISVVQGVIPPTVYDVVNTAKSTAKTTSLRTITSFFLPRNTAKVINIDSKTTARKMIVTLLKKFRVADNPRKFALYECEQITDEATCTLNRKLTRISDDACPLKVVLNWQSPHCGRALVLQENDTGDILWDAFEIPELENFLRILGMEEKQYVFQTQQKYQQYRYHLDAELRQRGHSVPDAAAQPMVQTNPFLDEEFLRNQDEYGTSDSMLFSGTIKNAIMGEDPDYVNLEYLKKQNMDQSTNL
The following text describes a protein:
Function:
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells.
Subcellular Localization:
Nucleus. Cytoplasm.
Domain:
The C2H2-type zinc finger 5 is required for nuclear localization.
Sequence:
MSQPVFPTASGIFLPDLHHDEVSAPQLVMLANVVVSAEASASEYSTEGKQMMELQTVACSSYSDSEEDDDAVVRYSMDTSEDLYTQQASHIQPEPVLEEIEIVRVGRPPNQTESTENAASAEQKRTTLAILESSRKKKKPFFCKPCQYQGENEQEFIVHIRTHGTKKMLVVNGGDSDEDLSADAGPQTSVPNAESAESNSKGVIRCERCGYNTNRFDHYMAHLKHHTKEGEDQRVFKCTICAYTTISQYHWKKHLRNHFPSKLFTCSQCSYFSDRKNNYIQHIRTHAGERPFQCIYCEYSSSQKTHLTRHMRTHSGERPFKCDNCSYLAANQHEVTRHARQVHNGPKPLSCPYCQYKTADRSNFKKHVELHVNPRQFLCPVCKYAASKKCNLQYHIKSRHPGCKDISMDVSKVRLRVKRSDGDDASPNKLTAEQAKIMEELEDAGPINLSIKKPSKLNAVVETEKSSKKNMDGKANQPQPNEKKSSSKNDPKEKTAKKLKGKTAVKDTEETQTEDTRVNNKKETKKAVKSAEKALKSRQKKEKPVKDSSVQQQSDDCEQTQHTPQQNETQENRPEKENRSLTEIANAKDCGKVQTKKPCKKQTKTLKVCGETQNVEEEEIMRQKAGKRKAENPAEPKQRIKRTKKKKDSGKPTTSEANQTNPEVMESESSEANNASKPDDSIDESQNPPVAESRPDVEPPTVSDCPIEKAPAVEDVQRPLEAEISTAAPDAPEVDSGNEMPSPTDSDGAPGFTPTLPLQHKPTDAEDDEGIHSNDGGSDISDSASEGSYDSGLMAGAEKLPETPTEERDASAARLLSHTCIFCDRSFALEMDYRKHLNRHLVNVYYLEGAAQGGK
The following text describes a protein:
Function:
During the late stages of oogenesis, dephosphorylates 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit ama-1. Similarly, dephosphorylates 'Ser-5' of ama-1 in early embryonic cells prior to the activation of the zygotic transcription program at the 4-cell embryonic stage. May dephosphorylate 'Ser-2' of the ama-1 heptad repeats YSPTSPS in embryonic somatic and germline cells.
Subcellular Localization:
Nucleus.
Sequence:
MDIKFEGNDAECTAGLKKASEGSFVLKDHVLIEFKINGKVAGKIKTPCEGVVTFGKGLKPGIVLNKGQVIATVSECTHAIVIKDMCATCGKDLREKGGRAGQRKEQSTANVSMIHHVPELIVSDTLAKEIGSADENNLITNRKLVLLVDLDQTIIHTSDKPMTVDTENHKDITKYNLHSRVYTTKLRPHTTEFLNKMSNMYEMHIVTYGQRQYAHRIAQILDPDARLFEQRILSRDELFSAQHKTNNLKALFPCGDNLVVIIDDRSDVWMYSEALIQIKPYRFFKEVGDINAPKNSKEQMPVQIEDDAHEDKVLEEIERVLTNIHDKYYEKHDLRGSEEVLLDVKEVIKEERHKVLDGCVIVFSGIVPMGEKLERTDIYRLCTQFGAVIVPDVTDDVTHVVGARYGTQKVYQANRLNKFVVTVQWVYACVEKWLKADENLFQLTKESTPPVGRPLGSKYVNDLANMDTIGKAALADMNNEVDEALSDDEDDGDNEDEDDDGNDVGEDKGDENLEEKQEKNEEEMDDVEQNGSVENQSGDALENETDSTSRGQKRKHCPEMEDEEEESDSDNEDDDTPMSYKALLSDSRKKGRIVPENEDDAVFDVDDEKGHAPANIDEEEDDEDNEDEEVPESDDDDEFEDMAALIERQISDAVDEKDQ
The following text describes a protein:
Function:
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNFTNITNDTYPDVLFSTFNYETPITALLIVSFALVFLLCVIGNSIVCFVIIRTPKLRTVTNYFILNLAVSDLLLAIFCTPFTLVYHVLTEYPFGEVMCKLTPFVQGISVAASVFTLLAIAYDRYKAIVFPTETRMSIRTMQKLLVAVWLLAVVIMIPQVFNMHLRDLASATFCVEIWPDVMFHKIYTVLLMCFVYIGPLVCVSYLYSRIVYRIWYRPNPSNDHAAATGPNHRVRQEEFVGAVPKRRVRVIKMLILVVVLFTLSWLPLYTLWILHDFVDLPESVRRFIDMNIFPAAHWLAYSNSCVNPLVYGFYNSNIRQKILSMFSCDNKNDCVLRMKKAPAEAHPLPEQQYHRRASGRRVNIVQETAL