lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MNTHNTTTVNVAPSAPVVHINELLPLLHKPDEQVGGSVGFTPLVANVAGSNGAAILTGASSVSDSASEPVRVDPDAGAGSTGAPNVNVSLVANSNLAILNRLLSAHMGASGHGSEQGRNSGGSGSSSSSGGSSNSSHKKCPYHRQCSSHHHLHRHLQHQQQAASGSSFAPAFCRYRNDGSSSSSSSSSSSSGSNGSGNASAISYPVRDAISANVSPPPVNAVILVDRYLLMEPVEGNNLYRCYDIKSHEELVCKIANNPCSNLLTAHFRLDGHRHVNSLHKVIQGNNQTYLLYSPSEGDLHSYVRVRKRLREPEARRLCRQMCEVVKSCHEQGIVLRDLKLRKFVFADRERTQLKLESLEDAVVLDDPAEDLLQDKRGCPAYVSPEILRVNTTYSGKAADMWSLGVILYTMLVGRYPFNDSEHASLFAKISRGQFTVPECLSSKARCMIRALLRRDPEERIASEDVLHHPWLLHDDSKDHAYGGLHSSSRSSSSGTAFDDHCVPEWYDPTDENDIGGGSSSSSSSSRMHYSFATGDAFDN
The following text describes a protein:
Function:
GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor, and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity).
Sequence:
MRVIGVIGYKDSGKTTLIEEILKHSDKKIAVIKHTKEDVEVDKKGTDTYRLSNAGAKITVLATDSKTVFFTDRMDLENILSVLSDYNIDFVIIEGFKEALKRLNIPKIVMLKDKDGSDLIDDHTAMIIEDYNYNIDDVLKVIYEKAVVPTMNLNCGHCGYNCRTFVKAVVKGEARWDDCVLAKGIKIIVDGKIIPAVPFVSKIVGSTIKAMIETLKGVDNPKTIKVEIDVSKLK
The following text describes a protein:
Function:
Plays a positive role in plant adaptation to phosphate starvation and exerts negative feedback regulation of SPX1.
Sequence:
MKFGKRIKEQIQESLPEWRDKFLRYKELKNLISSPAPVESIFVGLLNAEIDKFNAFFVEQEEDFIIHHKELQYRIQRLVEKCGHNDEMSRENISEIRKDIVNFHGEMVLLVNYSNINYTGLAKILKKYDKRTRGGLRSPFIQKVLHQPFFKTDLVSRLVREWETTMDAVDPVKVAEAEGYERCAAVTSAAAGEGIFRNTVAALLTMKEMRRGSSTYSAFSLPPLNISDSDNVLRSLHLSSPIPIP
The following text describes a protein:
Function:
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
Subcellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSKLKEISRQSTTSWSPIAQYPDYMAVGTVTGTIGADFDTSSKLEIYSLDITNESKQMTLKGSTSSSTRFNKVVWGQASSNFQNGIIAGAMDNGTINLWDPTKILASDATDGGGSDDQSSLIGVGQRHSGPVQSIDFNVQNPNLLASGGSDSEVFIWDLSDPTQPSALNPGSKSQQSSDITCVAWNKKVAHILGSASYNGYIVIWDLKSKKTLMTINDRNRKCKYRSIVWHPSEATQIVAASEDDDHPVIQAWDLRNTTSPVKSMEGHKKGVWGLSWCPSDNALLLSTGKDNKTFCWNFDRQEILCEINDNNSRNNINNNSNNSNSDNNNGNTDPNAWNFEVQWSPRVPALLSTSSYVGKVNVYSLQDVNEKSTSGSSAGQLNALGIQEQTSQITPTIKHTPNWLLRPCGAAFGFGGKIAVFGRNKKVTAAANGATSPSSSSSPASSVQQSQLQQQQRVIHISHVTTEVDIVKSSEQLENVIHTGQYEQYCQEKIDQSTSDEEKSIWGFLKVKFAKDDRLKILDYLGYDIETIKKELKQFLGTLPELPIESGFNELPIENVDDQSKPEPTTTTTNETVHLEPVVDENNNVVDADSFFDTAASDANKEQQDDSSSSPSTKSPTTTTTPIEFPGDEKEQMITKALLVGDHNSAVECCLRLGRYSDALILAHAAGQELWKKTQEAYFEIVRSPFGRVVSCIVKRDFQLLVKSADLKDWKASLAILCTYAPPTDFKILSGILGDRLDKEASDLKSAILCYICAGDIDKTVDIWSRVSQQHQQQQRQSLTSSGNSITVLEQESNKDLQNLIEKVSIFRSACNGNSNNNTLNQVLSMKYAKYAEILASQGNLSASLRYLAPITNSQCKQEYGVLFDRVYRATSNHQGIPQPPFPFQLVDVYSSNQPIQQQQQQQQNKAQQVGHQHQHQHQHQNQHQHQHQHQHQHQPPQQQQQQQQQQQMGRQNTFNQPPQPMGQHQHQQQQQQQQPPIMMNQSPMQNNNNNRIPMMNQPPMMNQPPMMNQPPMMNQPPQMMNQPPQMMNQPPPQMMNQPPPQMMNNNQPPIMMRPMQPSGPSPMNPPPTMNNTQPPPMMNTMGGPSSVNNSQPPIIPMNGNPLPMNPMSPMMSDKSNQPPMNPMMNPMNPMNPMMNPIQPTAPPPMNPMIPQGGSPMINHPPPPMNPMINNGPVSTPPMNPMMNQVVPQNISPPQMPTRSPVLENKSSSPSSESFTSPAPKPNVHNKTPSIITGQLGVTTPSEGPSNEDTERFVEKLQRSIQELNGRTDSKVWEDANKRCQGLINKVSKKDISAEAFKALDAILASIVEKDFKKASDTYIQITSTPLWGEVGSQSMVGLKRLIDLGLKSH
The following text describes a protein:
Function:
Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Vacuole membrane.
Sequence:
MAPPKPSLRIDGESTPLIQDLEATRSTSNSGLFAHHIPNNFHPPSPSMSPGGASKIFFGANAPTDVQSLKNFICSSYVNVLLVAVPLSFISHFLHWGSMADFIISFIAIIPLAGLLGDATEQVALKVGSTLGGLLNATFGNAVEAIVGIVALSQNQLRIVQTSMLGSILSNILLVLGCSFIAAGFKFKESKFQATAAQASASLMLLACIALVIPAAYFSSFLDKINTGRGNAAIPSGQDLVNGLASGLQSHHDKTEFAHHGLLVISRGTSVLLLAMYILYLYFQLSTHSYLYEDSSSEPEEEEARMNFRTATGALVGVTVVTAFCAEYLVDSIDEFAQQAGIPKAFIGLILLPIVGNAAEHVTAVFMAMKGKMELAIGVAVGSSIQIAVGVIPIMVIIGWATGKELTLFFANFETICLVFSVLLTTLLIQDGKSNYMEGAMLVSLYVIIGLAFWVS
The following text describes a protein:
Function:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA).
Sequence:
NARRGGRHYVPDRVRTETYRTAIMRHQSSIAGKVVVDVGCGTGILSIFCAQAGAKRVYAVDASDIAVQANEVVKANNLSDTVIVLHGRVEDVEIDEEVDVIISEWMGYLLLYESMLGSVITARDRWLKPGGLILPSNATLYMAPVTHSDRYSDSIDFWRNVYGIDMSAMLPLAKQCAFEEPCIETISGENVLTWPHVVKHVDCYTVTLGELESVTTKYKFKSMMRAPLHGFAFWFDVEFNGPATSPTSNQVSSSFIESSNNQSTDVSQRKKRANPSEALVLSTAPEDPPTHWQQTMVYFYDPIDLEQDQLIDGSLTLTQSKENRRFMNIHLEYTSGGRSFVKESVMR
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MTTTTFFLFLIPVLAIILLAVNLILSPHNPYQEKDSAFECGFHSFLGQNRTQFSISFFIFALLFLLFDLEILLVYPYVVSAYTNGIYGLVIMLVFFLVLTLGFAFELGKNALKIESRQVFNFNYKSWNGYSLIYS
The following text describes a protein:
Function:
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
Subcellular Localization:
Periplasm.
Sequence:
MMKMRWLGAAIMLTLYASSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNSDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATTVKRIKYSPDYFNFGNVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFREFWIERPKPTDKRLTVYALLDSPRATGAYRFVIIPGRDTVVDVQSKVYLRDKVGKLGVAPLTSMFLFGPNQPSPTTNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSYAMENPQGFGLLQRGREFSRFEDLDDRYDLRPSAWITPKGDWGKGKVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTLTFSRDEDKLHAPDNAWVLQTRRSTGDVKQSNLIRQPDGTIAFVVDFVGADMKKLPPDTPVAAQTSIGDNGEIVDSNVRYNPVTKGWRLMLRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MQLPVLILALLGCSHITASLVSQLDASMPMDLLLPPPAVSKSQQLFVLESVNNIIDLTRTIYRQETTIVVQPTDNKQTQSETIFYLAQPLEASNKVLALFEVRVKNKKGQLLAIRKDVAHDHLQYYTVTLPATTLGKTTLYVKSIYTKHVIPYPRKIKQLEPQLYEIQGNAHFLTPYKSTRQRTTVKLPNRKEPSTYTKSPKPVTRKDETIIYGPYLNVPALSRSPLYVHYADTQAVLLAKEYTKYVEVSHWGGNIAVQEDYELHHKGAELKDHFSRIDFKLSAQAHSETNVVKDLTAILPKGARNVFFKDTIGNVSTSHFRNDRESSMLWIQPRYPLFGGWRYSWFHGYDVSAESFLKKISANKFVLQLPFKSSVKDITAVSAKLVAVLPEGASNVEVATSLDVDQISESVIFSYLDSTGRPAVTIQTKNLIDDLEGVVQITYSYDTMRLLQKPFVVFVYTLGVFFIFIIYSRLDFSISPDVAKDKEERLEIYRIKISEIVKMDSRRFTDVSDAFEHFKSTRNLKMLDQVYKTADKDSADMYRNLDDIATLATLIDKSFGQSVQKLIDLLKERTKVARTMQQEVQNFIKDTSNGSDQAKKRAMNAQINQSLAKVDALCCRIASVLEHVGE
The following text describes a protein:
Function:
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
Subcellular Localization:
Nucleus.
Sequence:
MEKNISSMKFCVYLLTSINPGFKYHTYIGKTTCPPRRIKQHNGIISGGAFKTEAKRPWEMVIVVHSFPTQTKVLQFEWDWQHPEKGRRVRQAFDNMKGKHCGTMFSLQYKIRLLAEILQMPAYCKLPLSVYITTHRYDNFLNDCPPLPKQITVEYGDLNDIMKCVGIARIDRKEKTKIKHDNIFDNLHGTSQSQLSQLIEDFHLDDKTSQEVTVTEEQKKIQMQKELKEIQNTSSNCFICQQRIKLDQRIVKCLYKCGMKAHLCCLGKMFSENTHTLIPTTGNCPKCQREIRWGDIIKVLKNKTIESF
The following text describes a protein:
Function:
Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Also required for repression of GCN4 mRNA translation by the upstream open reading frames (uORFs) under conditions of amino acid sufficiency.
Miscellaneous:
MISCELLANEOUS: Present with 2580 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MNALTTIDFNQHVIVRLPSKNYKIVELKPNTSVSLGKFGAFEVNDIIGYPFGLTFEIYYDGEEVSSDENRDSKPKNKIPIGKVRLLSQEIKDVNNDKDDGQSEPPLSIKEKSVSLELSSIDSSATNQNLVNMGSKAQELTVEEIEKMKQESLSSKEIIDKIIKSHKSFHNKTVYSQEKYVNRKKQKFAKYFTVEYLSSSNLLQFLIDKGDIQRVLDMSQESMGMLLNLANIQSEGNYLCMDETGGLLVYFLLERMFGGDNESKSKGKVIVIHENEHANLDLLKFANYSEKFIKEHVHTISLLDFFEPPTLQEIQSRFTPLPKEEARALKGGKKNSYYRKLRWYNTQWQILELTGEFLYDGLVMATTLHLPTLVPKLAEKIHGSRPIVCYGQFKETLLELAHTLYSDLRFLAPSILETRCRPYQSIRGKLHPLMTMKGGGGYLMWCHRVIPAPEPVSENATAADSSEKLAEHGAKKQKI
The following text describes a protein:
Function:
Promotes actin polymerization mediated by SNX9 and WASL.
Subcellular Localization:
Cytoplasm. Perikaryon. Cell projection. Cytoplasmic vesicle. Note=Detected on neuronal cell bodies and cell projections, in part on cytoplasmic vesicles.
Domain:
The F-BAR domain has an atypical, flat shape and binds preferentially to flat membranes (By similarity). Upon heterologous expression, the isolated F-BAR domain is localized at the cell membrane, and causes the formation of cellular protrusions (By similarity).
Sequence:
MQPPPRKVKPAQEVKLRFLEQLSILQTWQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKREGHRSGEMDSRGRTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTGRSAKEQVLRKGTENLQRAQAEVLQSVRELSRSRKLYGQRERVWALAQEKAADVQARLNRSDHGIFHSRTSLQKLSTKLSAQSAQYSQQLQAARNEYLLNLVATNAHLDHYYQEELPALLKALVSELSEHLRDPLTSLSHTELEAAEVILEHAHRGEQTTSQVSWEQDLKLFLQEPGVFSPTPPQQFQPAGTDQVCVLEWGAEGVAGKSGLEKEVQRLTSRAARDYKIQNHGHRVLQRLEQRRQQASEREAPSIEQRLQEVRESIRRAQVSQVKGAARLALLQGAGLDVERWLKPAMTQAQDEVEQERRLSEARLSQRDLSPTAEDAELSDFEECEETGELFEEPAPQALATRALPCPAHVVFRYQAGREDELTITEGEWLEVIEEGDADEWVKARNQHGEVGFVPERYLNFPDLSLPESSQDSDNPCGAEPTAFLAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFPSLLVEELLGPPGPPELSDPEQMLPSPSPPSFSPPAPTSVLDGPPAPVLPGDKALDFPGFLDMMAPRLRPMRPPPPPPAKAPDPGHPDPLT
The following text describes a protein:
Function:
Stimulates activity of the acetolactate synthase catalytic subunit ilv1.
Subcellular Localization:
Cytoplasm.
Sequence:
MFARRCGRLANRFVRLKSTSATSPITYKALHANSPLPRCRIIEPPRATVPEAVSNIIMSTPFNRVQRPKRHVFNCLVQNEPGVLSRLSGILAARGFNIDSLVVCATEVENLSRMTIVLRGADEVVEQAKRQIEDIVSVWAVLDYTGTSMVERELLLAKVSLLGPDHFQEHFERSEKVAESTNAKAKSDGEGVMNANAALQLRASQLAAINQLTTLFHGRVADISTETIILELTATPDRVDNFLSLLRPYGVLEACRTGTSAMTRAPHSNEVTEEAEDDVEVEEVFLPPG
The following text describes a protein:
Function:
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
Sequence:
MKKIGIIGGGQLGKMMTLEAKKMGFYVIVLDPTPRSPAGQVADEQIVAGFFDSERIEDLVKGSDVTTYDLEHIDVQTLKKLYNEGYKIHPSPYTLEIIQDKFVQKEFLKKNGIPVPEYKLVKDLESDVREFGFPVVQKARKGGYDGRGVFIIKNEKDLENAIKGETYLEEFVEIEKELAVMVARNEKGEIACYPVVEMYFDEDANICDTVIAPARIEEKYSKIAREIATSVVEALEGVGIFGIEMFLTKQGEILVNEIAPRPHNSGHYTIEACVTSQFEQHIRAIMNLPLGSTELLIPAVMVNLLGEEGYYGKPALIGLEEALAIEGLSLHFYGKKETRPYRKMGHFTVVDRDVERALEKALRAKKILKVVSEEGAMCQG
The following text describes a protein:
Function:
Receptor for persephin (PSPN), a growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons. Acts by binding to its coreceptor, GFRA4, leading to autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
Subcellular Localization:
[Isoform GFRalpha4a]: Cell membrane; Lipid-anchor, GPI-anchor; [Isoform GFRalpha4b]: Cell membrane; Lipid-anchor, GPI-anchor; [Isoform GFRalpha4c]: Secreted.
Sequence:
MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRCARAAAGPWRGWGRGLSPAHRPPAAQASPPGLSGLVHPSAQRPRRLPAGPGRPLPARLRGPRGVPAGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAIQAFASGWPPVLLDQLNPQGDPEHSLLQVSSTGRALERRSLLSILPVLALPALL
The following text describes a protein:
Function:
Probably functions as a 3'-phosphoadenylyl sulfate:adenosine 3',5'-bisphosphate antiporter at the Golgi membranes. Mediates the transport from the cytosol into the lumen of the Golgi of 3'-phosphoadenylyl sulfate/adenosine 3'-phospho 5'-phosphosulfate (PAPS), a universal sulfuryl donor for sulfation events that take place in that compartment.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MGSGIEVNDSSTTNSNNNEKVQLSYNMKLALATGGIMGSFLLYGILQERLMVVPYKNADGSEEYFTDSTFLVLSNRVFAALMAIVIVLKRGESLKNVAPLHKYVGVALSNFCATWCQYEALKYVNFPTQTLGKCGKMLPVMLVGTFISGKKYGLKDYSIALTITTGCMIFFLTGKISNNESSNTSYGIILMALYMFFDSFTSTFQEKMFKGYTMSTYDQMIYVNGCSSIISVFILILNGRLFPAIEFISTHNGVFFDSTMLSASAGLGQMVIYYTIKEFGALVFSTIMVTRQMVSIILSTLIYLHPLSNTQWIGALLVFGTLYYKSIEDSKKKHGGHSHGGSNAATTTTPSNNSNNTEK
The following text describes a protein:
Function:
Endosomal receptor that plays a key role in innate and adaptive immunity. Controls host immune response against pathogens through recognition of uridine-containing single strand RNAs (ssRNAs) of viral origin or guanosine analogs. Upon binding to agonists, undergoes dimerization that brings TIR domains from the two molecules into direct contact, leading to the recruitment of TIR-containing downstream adapter MYD88 through homotypic interaction. In turn, the Myddosome signaling complex is formed involving IRAK4, IRAK1, TRAF6, TRAF3 leading to activation of downstream transcription factors NF-kappa-B and IRF7 to induce pro-inflammatory cytokines and interferons, respectively. In plasmacytoid dendritic cells, RNASET2 endonuclease cooperates with PLD3 or PLD4 5'->3' exonucleases to process RNA and release 2',3'-cyclic guanosine monophosphate (2',3'-cGMP) and cytidine-rich RNA fragments that occupy TLR7 ligand-binding pockets and trigger a signaling-competent state.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Domain:
Contains two binding domains, first site for small ligands and second site for ssRNA.
Sequence:
MVFPMWTLKRQILILFNIILISKLLGARWFPKTLPCDVTLDVPKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVPIPLGSKNNMCIKRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNIFSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTAVPTVLPSTLTELYLYNNMIAKIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCAPCKNNSPLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPSGDSSEVGFCSNARTSVESYEPQVLEQLHYFRYDKYARSCRFKNKEASFMSVNESCYKYGQTLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWVNHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTCELDLTNLILFSLSISVSLFLMVMMTASHLYFWDVWYIYHFCKAKIKGYQRLISPDCCYDAFIVYDTKDPAVTEWVLAELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVAYSQVFKETV
The following text describes a protein:
Function:
Acts as a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
Subcellular Localization:
Nucleus.
Sequence:
MEGFRSYFQRLVVGNAGQIFPNQKWQGVNSTTYHQLVAEVKKLSQDFEQSRRIAEAIETGTEDLFRDFDLSTFMEHFKLDAFEKTVLALAFKLGSKPDLKTKADAILSTNFPMFGNILSKSSGTHTMLGPDFIAGLLDRFIQVHPPNFNAAAKKELEHNVQSRYIQGNPDSNPLPPSQVLSALDLMRLLADRPPNALTLYIHKTGQDFTENEETCYNYLRNRPANCQLSEEQVSHALMYTTISQTPPHNPSVLVTALRRVLPGTFRWQDVVSYFDHSGARITAPQFLRLYNALLPIAQDDSQGFDIQRLWGGEWENPETQMSFVCAYTSLLPEQLDATTIPGLKPTFTLDDYAQAPQMIRETAAYAVRHPLVSEAAMSAIFNVALHSTHASKCTEAKRLFQDVVVPQVAIFVVSAFRVPKPWPKLAEDALVDLFIESLWAAKSPETDFVMNSLWRWDKDWVKMRLIDAHAHRPICLPQIFEHSIRQGWLEELVYLINGFGFDLTALAHAEGYLDLQEWAQKNAERSTEMASALLQFLMIKANLELQYQRSGPGAPKQSTTLQVRTVSAMLQILEEFLPKSPIPELIVVQRQCITAYPRLINYGEGFDDIIDANGRDGNSLPQAANVRMEEHYKKMYSDEVAVRTIVEVLDQYKHSRDPLEQDTFACMIHGLFDEYAHYENYPLEALATTAVLFGGIISHKLVSELPLKIGLGMILEAVRDHQPQEPMYKFGLQALLQLLPRLREWPGFCTQLLLIPGLQNTEARKKAEDVLREHEEETMRARGGALPLGATMGNDNMTNGNLDEAHGSEQHPPPFASVNVDPPPPGVIYEDPTAEAQGKIQFFLNNLTETTLQTMYKDLRDMLETKHQQWFASHLVEERAKMQPNYHQVYLDLVKMFEDKSLWAEVLRETYVSVQRMLNSDVTLQNSTERTHLKNLGGWLGLLTLARNKPIKHRNIAFKQLLMEAHDTKRLLIVIPFVCKVLAQGASSEVFQPPNPWLMDIIHLLIELYHNAELKLNLKFEIEVLCKGLKLDHKSIEPSGEILNRVPVEEVPDLNGQELEPYDNTSINGMGSVAGGLPAHASLPIPDLSASLSIPPTEVIDQAKLHSITSQAVTRALQEIIQPVVDRSVTIAAIATQQMIHKDFATEPDENRVRDAAINMVKSTAGSLALVTSKEPLRSNMANYLRALSAEIGLVLPEGIIMLCINSNLDLASSVIEKSAEDRAVPEIEEMIQPEIEARRRHRAQRPNEPYMDPGLTRWAWTIPHPFKLNPSMTGLNAEQMAIYDDFARQPRAVASTTGPSHAASTSDARSLANEVLGDQFNTISALPTPAETPSLPHLGGQLQHYPQGSGGLANGRQAGLNQVDARTIADRVNKLLESLTAAATGATEEHFNELPRAHQVLDIIDALVQLIIKTQQTSEEFAAYAATQIAQLIFRQPGDTLLLESLVHVLETLRKIAGPATSQQIRSLFHQQPAEYFLNLSLIAALLGTDLLDWRSIDAAMSMALQQRKEGSVEFLEQLVDLTLLSESPLALYADFVRSLEEAWAWISENPDVPGGQSLKSKILAPPPDLPEGLTPAEILAIRQDQMEYVFDEWVHLCNNPAASSSKSSTIFVQQMRSRGVIASTDDFLMFARLAIDKSVDRFEHVVHLNGTITEAYQAIDALGKMILIFFQSHEDNADGQTARAAFIDSILALGVLVLNSHHVKRGDAFNSRVFVRFFSYLLHGIHSLEELPENERDRFMLSFAERLYDLRPSLYPGFVLGWLTLVTHRVFQPAMLQMANNAGWEAYTKILRDLLSYQGELLKPLELSIFAKEMYQAVLKLLIILGHDFPDYVSANHVLLCQSLPPHATQLRNMILLATPASAAKPTDAFQPGLKLDQIADIKEAAISVYDPAEQLRQLGLLDILDQALQNGPSEDAIAQITHAITRTGSGTTDYGFVPIDVNRQVIDAVITHIGNFAVNRAATRNDASVFVPGAPDLKTLQMLITELSPDTRYFVLNSMANWLRFTSAHTHYFIQVFLDFFGHDVASTDPEEMDIRQQIVRILLERLIGYWPYPWGLIITTMELVKNEKYNFFELPFIKATPEVRRVFEDKVRQH
The following text describes a protein:
Function:
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQCSPTLKMQAPRDDLVVFTTTVMPTVPPACDKMPTETNRSDGISTINVTDGYQMGPVDKGSPLPAIMLHLVAYLTVFIVCILGNLLLVFLIRRKPHLRTPALCFVFNLGFADLLVGIFCIPYDLFHPFFSQEEGLGFLMCRVSNTLQGVAISGSAFTLTALAVCRYRLMTSTKRQQEDARKALPFLALIWTTSAAISLPHFIFVTSADNRKSSRIRRFCDEEWTSSQYSFMYKGFLMAVCLLGPVFVNVLLFFAEKYPRCREPLESYSVSQVTKHSPIEELKEDFPTISRRKDPPPLTHSKRLTTTSSILSVIRMAFLLTWLPLYICWMLDIYFDLPTKYAKRLHDYIYPISHWLAFSNCVVNPLVLIYFTRRREKAAQIQRKGRMSRRRYCVEDGKLQICSEDDK
The following text describes a protein:
Function:
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
Sequence:
MTSDDTVRPGRPRSIETLAELTPEQTDAVLALLTEAARTDGQHAVSEQGRLQLRGPAREGVVHLLLTLDGGELVGYAQLEGTDPVEPPAAELVVHPSHRGQGHGRALGSALLAASGKRLRIWAHGGHSAARHLAQVLGLSLFRELRQLRRPLTGLDLPEPRLPEGVSVRTFVPGQDDAAWLAVNAAAFAHHPEQGSLTQRDLDDRKAEPWFDPAGFFLAERDGELIGFHWTKVHAEERLGEVYVLGIRPDTQGGGLGKALTTIGLRHLEGQGLPTAMLYVDADNKAAVAVYERLGFVTHETDLMYRTET
The following text describes a protein:
Function:
Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
Sequence:
MLDLVKIFGYPVSPCPLVYLDDTLSQFKDPNCRSQPPMIFRSTWNDSHLARQKIKSYCGLFIGSKDNLRKWIGHPKFELIHHDVTEPLLIEVDQIYHLSCSASLIFYKYSPVKTIKTNVIGTLNMLGLAKRVGTRILLTSTSEVIEHPQKGEYWGNVSPIEIRIARIFNTYGPRTNIDDGRVVNNFIVQALRDEPLTVQSPGTQTRSFCYVSDMVDGLIRLMAGDHTRPINLGNPGEFTRMELAETVKEGSVHFIMLRTIVLKDYCSSDEQLFKDLVAQFFMKLVE
The following text describes a protein:
Function:
Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Sequence:
MDIETAACFSIAFIATPILIVLVRLLFILPSLRLPTSVKKKKKLIQECQLSILLGSGGHTGEMMRIISKLDMGKVSRTWIYTSGDNASLAKAQDYERKSGTSSQYIPIPRARTVGQSYISSIPTTIYSFLFSAIAMLKHRPAVILLNGPGTCVPVAYILFLYKLLGLCNTKIIYIESLARVNKLSLSGLLLLPISDRFIVQWESLYQQYSRVEYYGILI
The following text describes a protein:
Function:
May play a role in the organization of actin filament arrays within muscle cells.
Subcellular Localization:
Cytoplasm, myofibril, sarcomere, Z line.
Sequence:
MPQNVVLPGPAPWGFRLTGGIDFNQPLIISRITPGSKSSLANLCPGDVILAIDGFGTENMTHAEAQDRIKAAMDQLCLKIERAETRIWSPQVCEDGKAHPFKINLEAEPQDLGYFEHKHNIRPKPFILPGRSSGSSTPSGFDPGSGRSTPSSVSTVSTIDPVELKAASRIAPNVPLEMELPGVKIVHAQFNTPMQLYSDDNVMESLQGQVSTILGEKTPMSDPVPPAVPQSDVYKLLHDDTEHPNKPRQSGSFKILQDMVDDDPDRPAGTRSVRAPMTKPSTGAAAVQKVPVCDRCGNGIVGTVVKAKDKLRHPDCFVCTDCNLNLKQKGYFFVEGQLYCEAHARARMRPPEGYDAVTVYH
The following text describes a protein:
Function:
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).
Subcellular Localization:
Cytoplasm.
Sequence:
ARSGRSHHALRRTHKYPFLRVRFPPSCARFHRYATLFYNLTSMSGGTPGGGSGGGGGGGTAAGGTVEKGGAAAGAKQLAGEWSQSLQECAMSNESASGGLTFLRSLTSGGHRWSSSSHNRPTFCNVCREKFTGVPWHGMACEICKMKVHKRCAEAVRECCKWTMAESIPAPMQYINPENSIGPHQWLQGNLPMGSRCAVCEKACGSVLKLQDLRCLWCAQCVHDSCESSLPRYCLLGTSALSVLPPIALERVDKNGRAKIRDDAVGGDYGGGSPLLVIVNSKSGDNQGSRLIRKLRRLLNPIQVFDLIACGPEFPLTFFSHFDTFRVLVCGGDGTVGWVLTAIDKLAMHNKVQLGVLPLGTGNDLARVMGWGHSFYNDARLPNLIRTYERAHTRMLDRWSIMAIEGVDPTYGKMHDQIAAKVTAFMHAEAPHDVFAAIKDLGVCVHELILTMQSTYDQVESWERQFGRNTEDPLTDKFRSLMTRLNPLIKELNEVTTMEESGVESADSAATEEERARRERLVLRANSFKKTIMEVLEFTEKTVDRHNREARHGSAAAAKRDRFRKKRSKTTPSALKVSGSNVSSGSAYSPPASPSVISPSRQPRVSLGASVDSHTNPLATARDLRTQRPIDEQDDVEEEEGATEEEEEEAGPSYFVHPPTPCSSRLDDSYEQEKAGGRGDGDRGGQEGGRGDEKRKEEKEGKDEVGRTEGRREMRQSTSDGGLYLGRKRSEEEGRSASSTAEEEEETAEEEGIAATTATGAAGDMLSPSGGSAVKRRGRPQTHSGVSLPCGSSLSTASSSFTGGVCGSGGRYIPSTERQRQSTFMDRLPALKKGILSSGLTGGTLIAEMLMLSANVLKTPTALYGDVTHESLPDYKELKVMNNYFGIGLDAKIALDFHNKRESTDKQRSRSKLFMWYGILGGRELLHQTYRNLDQRIRLECDGLPIDLPSLQVVALFGVVHVASGRIPNVVRLQNHRIAQCRHVKITIHGEEPIPVQVDGEPWMQPPGVLQFVHKNRAQMLVKNAQSFDASLRTWEEHKSVTAPSTPTALNTTLPQDGDRVPFSRRAAAFVSTIESEMAHLGLTAKFLDTLEHTATVVRRAEHAEQEVKDCRDTEDRG