lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for maintaining multiple types of adult stem cells, including male and female germline, epithelial follicle cell and intestinal stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4). Controls selective autophagy activation by ubiquitinated proteins.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPVSLAVCETTTTTTANVVNAALRESLLGGSRSGAAVAGSGSASSLISGAGGAGASAANDDDSSSTATANTNLQNQIVASAKRVLLAKIEYEEVENYNDSVLDNLKTKYVVIKSPTPAAAAAATNNGNSNSAGSKILGANGHDNRQKQQNANGGCSTPTTTTTQTSSSSTSSSSIEHNNNPNELPKPKRVLYQRENIRIGWKQSERKWQIGAGMINVGNTCYLNSTLQALFHIPALANWLNSEQSHLENCNIGGESGGGGGGGGGNNGGFCIICAMAKTLQSTQSNASAIRPYHIYSKLKQICKHMVIGRQEDAHEFLRFLVEAMEKAYLMRYRNYKELDQLVKETTPLNQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKSDTLDEAFDGYFSRERLEDMGYKCEGCKKKVSATKQFSLQRAPITLCIQLKRFSMIGNKLTKQISFKPRIDLSRFAARSPTAQGQLPLTYRLVSLVTHLGVSQHCGHYTAIGLTESGSYYNFDDSYVRPIAMQSVCSTNSYIMFYELDLNQPLATPANKLNGLRQLSNGHHHHQQQQQQHQQQQQQQPTVVATIASSPMATTRFIGPQLPPGGLNGYAMTTTTTATNNTTNGHSQKTAIQFKPQQNGILTVGSGKFQESGQQKSPLVGTNHKNEAPAVAPNANANANGKSSSNPNTNTTINTNTNNGNSNNNNTNATTANNSNKLNQQQQQYLPMSSSDEEDSDEEKMKRPTTTTPQLPSMPKMDGGGDEKPKTLTLTPTTTPTASTPTVSNPLKRLVPYESASEEEESSSGTPSSSTPTTTTTAAAAAASSPMQATAAATLPPPPTPTNARKRSLPDHHHHHPHHHVMVNGHGKSPKPASMPPATNFNSSSSKQKTDAIDEIFKSLNNFNKKRINNKNQKHNEGDEEEDDEETLEKETNNSSRLVSSSTNTSPTTNGWKQSQIVSSSSSNSKNVSTSAAAAAATTSSSTSTSAPPSPKTPPSPAVINSKTGLWKVTRNLDDDDDEEEEDEDDEEHIAPTPPPVVAKTHKNPFSSQQKPTPSPSTEAAPKRQKLFNGTSSSTPHVGNGYQSEPSTPNGGGSGSGSNGCLNELLKQSHRGYGSSSVLSWNGKQTELDKEPFELVCAKRIAVDHGDHDDGGGGDDGGGVGVVTTTTTTTTTTKNTTKTLTADAQEQRQRDLDDDEENEMDRGRQRKVKTATANGKSSGNSNNTTPGYNPFQEYESQKRWHNKSSNGPPRFYTQHASSSYRSNFHQRNKFKCNRGGNGGGGSGGISKFDHRHGLQRHLAAGGGFPRRPNANQQQQQQQS
The following text describes a protein:
Function:
Putative Notch ligand involved in the mediation of Notch signaling.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
SASGFFELEVVALQNPQGRLANGQCCGLVAGEETSSTCQRECATHFRLCLKEYQSNVTVSSPCTYGNASTPVLAGNSFTFVEPDKSNARLVIPFSFRWPRSFTLMLEALDYRNSTRQSGEIERAVYSGILEPSADWHSLTHEGSGVNSDLRLTYRVRVQCEPHYYSATCTKLCRPRDDLFGHWECDRNGDKTCMPGWTGTSCDTVVCKAGCHPINGDCKEQPLECRCRPGWQGEFCDQCVTYPGCKHGYCNGPFQCLCETNWGGYLCDQDLNTCGTRQPCRNGGTCENTNPDQYQCKCPEGFSGINCEVVDNVCATAPCLHGGTCTVTTTVVTNGISDSTGGGGSFNCTCPPGWTGDTCQIKVDECQSSPCLNGATCVDLENGYRCQCAQGWQGDTCDQDVDECSMPELCRNSLGCENTPGNYTCRCVTGFHGRQCQYNVNDCNGHHCLNGATCIDLIGEYHCACRPGFNGHRCEINMDECASRPCANGGECVDLVDGFKCICPLGYTGSQCQTDTDLCHPNPCANGSPCFNTLGPLGGPDYFCLCQSHWQGKNCSRYRPPPPPPPPPSSPSLQAGSCWTSKGAGHCVHGRCVASEDGSTFSCQCDPGYSGQFCTDNVNDCADSPCRNGGTCIDGIDSFHCVCPKGYDGLTCDHNVDDCASSPCRHNGTCVDLVADFVCRCVDGWKGRTCSNRNQHCQDGENPCLNGATCVDDSDPEAGFTCRCSSGWKGSICHLAEHMPCDAHPCRNGATCLNTGQSFTCVCKDGYEGQHCQMEQRQTAAAAASTTTSPASCQWSGRLYPDNSSWDDGCNKCQCRSGQAVCTRVWCGPANCLDDPINHVGKSCGPSEICLSAQSGCLRPPCPAYGQCRPLKPGRLLPVPAATASCWPNLTGNRLAPTCARLTLVLDRYRAQPGFSVQSLCGHLRKLAAAQSHLWDNFPGHQQPNLERPSLVILCDLKDHQDDVVQVTIVRSRATAAARVLGNVLTAYYKEGSSMGAVVDVKVETPYADEIELVLDSSSAQNHPSSDSSGSSNYVVAIVCAILAGLVVVAGLLLLLLWRLRKRPALHSPSLSVNSSMDRTVEKSNNLQNEENLRLQQRRIKTLNVAELVDHPAKGSLGLSKKLSKVDDVVVPHDDSSSDEYGRRDTIESSPIYKAPISVDVRNNIHMAARAGQMMDKELSLKVVVV
The following text describes a protein:
Function:
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKALQGVMAALLTPFDHQQQLDSESLRRLVRFNIGQGIDGLYVGGSTGEAFVQSLAEREQVLEIVAEEAKGKITLIAHVGTVSTAESQQLASAAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPGVSALKQTSGDLFQMEQIRRAHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVQALREGDVAKAQRLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFAPVDEKYLPALKALAQQLMEEKA
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MNRRIHTRLKDYSLVAVPPPPSRFTLQEWHLNNLLRNRNCYDQQTLADRVLAESDRIRDQVAEITLLNRREADHKLDEKLKDIQFNIDEIQKQRKEVCIEIDNLTTYSERILDAMESLKEQALKICKKCIILREGRIGIDLCHDQVEVELLKEIDVIEGAQKLLKRTLEQANEQIRRLRSTIYFMDRDLEDKSNVLKIDEHNRGLKETSLNLSIYHGFAPLDPANVTAEEWQQFTTTNIERAAKEINSARQLRCYVDTLLKQVIEDLRDQWHAVNEAFRARIEEVKEAKTKLETQHFEITRQANEMTRNVTRLEKAIAEKEGFMALAHTRLGNRAQRPGIELCKDLVETSLVNEPRRKRLCVICLRRKYSWRRT
The following text describes a protein:
Function:
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport.
Subcellular Localization:
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MVHAFLIHTLRAPNLEDTGLCRVLYSCVFGAEKSPDDPRSHGAERDRLFRKEQILAVARQVESLCRLQQQAAGCSSTDLQPQFSAEPVSLHEAPHGAFHLAAGDPFQEPRTVLWLGILSLGFALVLDTHENLLLAERTLRLLARLLLDHLRLLTPAVSTGAAYCRAHPSR
The following text describes a protein:
Function:
The absence of paraoxonase activity in turkey and chicken blood and in turkey liver indicates that PON2, if expressed, does not hydrolyze paraoxon.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MGRIANLGWTVHGLVLVPSDFYLSGPEKDGLRGQHFPSSDTTMVAAEQWVTAAGADVYENRLNATREVDPVALPNCHLIKGIETGSEDIDILPNGLAFISSGLKYPGLKSFAPDKPGEIFLMDLNEKKPKASELRISRGFDLGSFNPHGISTYIDKDDTVYLFVVNHPHQKSTVELFKFMEDDNSLVHLKTIRHDLLTSVNDVVAVGPDSFYATNDHYFSDFILMFLEMYLGLTWSNVVYYSPKEVKEVAAGFYSANGINISPDKKYIYIADILDHNVHVMEKHADWNLTHVKTLQLDTLADNLSVDPDTGDIWTGCHPNGMKLFYDDPDNPPASEVLRIQNILAEQPTVTRVYAENGSVLQGTSVATVYDGKLLIGTVFHRALYCEL
The following text describes a protein:
Function:
Allows the synthesis of deoxyribonucleoside triphosphates necessary for the rapid viral DNA replication (By similarity). Phosphorylates dGMP, dTMP and 5-hydroxymethyl-dCMP (hmdCMP) while excluding dCMP and dAMP. The phosphorylation of 5-hydroxymethyl-dCMP represents the first step in the replacement of cytosine by hydroxymethylcytosine in new viral DNA genomes.
Sequence:
MKLIFLSGVKRSGKDTTADFIMSNYSAVKYQLAGPIKDALAYAWGVFAANTDYPCLTRKEFEGIDYDRETNLNLTKLEVITIMEQAFCYLNGKSPIKGVFVFDDEGKESVNFVAFNKITDVINNIEDQWSVRRLMQALGTDLIVNNFDRMYWVKLFALDYLDKFNSGYDYYIVPDTRQDHEMDAARAMGATVIHVVRPGQKSNDTHITEAGLPIRDGDLVITNDGSLEELFSKIKNTLKVL
The following text describes a protein:
Function:
RNA-binding protein involved in post-transcriptional regulation. Negatively regulates expression of COX17 by binding to the 3'-UTR of COX17 mRNA. Promotes decay of COX17 mRNA by enhancing its rate of deadenylation and subsequent turnover. Predominantly binds to mRNAs encoding mitochondrial proteins and localizes them to the vicinity of mitochondria for translation. Regulates mitochondrial biogenesis, motility and morphology.
Miscellaneous:
MISCELLANEOUS: Present with 846 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Localizes to multiple discrete foci in the cytoplasm.
Sequence:
MEMNMDMDMDMELASIVSSLSALSHSNNNGGQAAAAGIVNGGAAGSQQIGGFRRSSFTTANEVDSEILLLHGSSESSPIFKKTALSVGTAPPFSTNSKKFFGNGGNYYQYRSTDTASLSSASYNNYHTHHTAANLGKNNKVNHLLGQYSASIAGPVYYNGNDNNNSGGEGFFEKFGKSLIDGTRELESQDRPDAVNTQSQFISKSVSNASLDTQNTFEQNVESDKNFNKLNRNTTNSGSLYHSSSNSGSSASLESENAHYPKRNIWNVANTPVFRPSNNPAAVGATNVALPNQQDGPANNNFPPYMNGFPPNQFHQGPHYQNFPNYLIGSPSNFISQMISVQIPANEDTEDSNGKKKKKANRPSSVSSPSSPPNNSPFPFAYPNPMMFMPPPPLSAPQQQQQQQQQQQQEDQQQQQQQENPYIYYPTPNPIPVKMPKDEKTFKKRNNKNHPANNSNNANKQANPYLENSIPTKNTSKKNASSKSNESTANNHKSHSHSHPHSQSLQQQQQTYHRSPLLEQLRNSSSDKNSNSNMSLKDIFGHSLEFCKDQHGSRFIQRELATSPASEKEVIFNEIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNTLVDQFKGNMKQLSLQMYACRVIQKALEYIDSNQRIELVLELSDSVLQMIKDQNGNHVIQKAIETIPIEKLPFILSSLTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELKDFIPYLIQDQYGNYVIQYVLQQDQFTNKEMVDIKQEIIETVANNVVEYSKHKFASNVVEKSILYGSKNQKDLIISKILPRDKNHALNLEDDSPMILMIKDQFANYVIQKLVNVSEGEGKKLIVIAIRAYLDKLNKSNSLGNRHLASVEKLAALVENAEV
The following text describes a protein:
Function:
Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum. Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3. By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis. Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens. This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MVGLHLCLIQCQDHHFHVLTDHYKDELHSKEFDHQVFLGVEEAQNFDKLTSENSKERLKVLIPEIDSNNDNLIDILELTNWIRTRQDKVIARGAEASFQLYDKNKDNKVSWDEIRSAKYGISDNSETAGILVVSQNVDLKEMKYDKEKYNHADTDGDLKLSLHEFKIWLHPESDPRMAEFLHQEALHKSDRNKDNLLEFKEYLGSNHDNIQEIEHTHDWLKEEKQKFDSYDKNNDGMLDLEEVRLYYVPVQFLNQLRNEARHLINKADKNQDQKLSVEEILDNSDIFVGSLPTTKHSSDEL
The following text describes a protein:
Function:
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein. Secreted.
Sequence:
MAARRSQRRRGRRGEPGTALLAPLVLGLGLALACLGLLLAVVSLGSRASLSAQEPSQGELVAEEDQEPLDLNPRTEESQDPVPFLKLVRPRRSASKGRKPRARRVIAAHYEVHPRPGQDGAQAGVDGTVSGWEEAKINSSNPLRYDRQSGQFLVTRAGLYYLYCQVHFDEGKAVYLKLDLLVDDTLALRCLEEFSATAASSLGPQLRLCQVSGLLPLRPGSSLRIRTLPWAHLKAAPFLTYFGLFQVH
The following text describes a protein:
Function:
Essential for both cleavage and polyadenylation of pre-mRNA 3' ends (By similarity). Involved in neuron development, probably by regulating pre-mRNA 3'-end processing.
Subcellular Localization:
Nucleus speckle. Note=Also localizes to a small subnuclear ring in neurons. In neurons, partially co-localizes with sydn-1 in the nucleus.
Domain:
The C-terminus is required for the regulation of synapse and axon development.
Sequence:
MNGGMMRGNQMPNVTLTIQPSTSSMQNSQPRIMNNHHHPHNRFQREHVMPDVMGDGPGRRLRKNVANVRRHVDYVSTVLNHCENRLWQYGKQRILQQPDILYQQYAVPADSTPDVPVDCILTKFIRTAMNKVKCPVYSVCWSPEGKRLITGCQTGEFTLWNGTAFNFETILQAHDSAIRALKWASNEQWLLSADQGGYVKYWQPNMNNAHMFSAHKDEAIRGLAFAPTDVKFATASDDGTARVWDFARYTEERVLRGHGAEVRCIDWHPTKGLIATGSRDTQQPVKIWDPKSGSCLATLQEHKSSVMAVEFNKNGNWLLTGGRDHLVKMYDIRMMKEMRTYRAHKKEVISLAWHPIHEGLFVSGGGDGSIVYWMVDGEKEIGLLEHAHDQAIWSMKWHPLGHILATGSNDNNTKFWARNRPGDTVEDIFGLSNTNMIGHLDKEREPRMAPPKPSIETQETYRPDTFIPGMGLDEHLYEQLNRDHNMMTTDSTLLVPDDLTRQNFAPMIGAKRTLIKQPPAKKAQRQFERMWNNSKGIGAGSDDFTTMKGGLGREDAEGAQFGPSKSFLGPPTTGGSLLGPSQPRPQEFRSVPPPQQQQGPPPNWRHQGPPMSGPGQGYGPPGRMGGNQGGWQRPPPQGSYGGQGPPQGSYGGQGTLQGSYASQQGPPPRQIQHIPSDIDYRTAPSSSNGSTGDVDMRTMVPNQPPSGEPEHWRGPPPVSHQQQSQQQHPPPINMQRMDPRRDPRMLSGRSDQLSPSGPPPQQQQSSAQQGGKNQWMPQFEAGQNQNQGNYAGNRGGGVGGRGRGRGQPY
The following text describes a protein:
Function:
Hydrolyzes myo-inositol monophosphate. Catalyzes the dephosphorylation of GMP and IMP.
Sequence:
MTNWTEIDEIAKKWIREAGARITQSMHESLTIETKSNPNDLVTNIDKETEKFFIDRIQETFPGHRILGEEGQGDKIHSLEGVVWIIDPIDGTMNFVHQQRNFAISIGIFENGEGKIGLIYDVVHDELYHAFSGRGAYMNETKLAPLKETVIEEAILAINATWVTENRRIDQSVLAPLVKRVRGTRSYGSAALELANVAAGRIDAYITMRLAPWDYAAGCVLLNEVGGTYTTIEGEPFTFLENHSVLAGNPSIHKTIFEEYLHARK
The following text describes a protein:
Function:
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MGEEEGGHVDVGLFETKEARFRGVYKVFASTIFGAICLIWMYRVGNIPTVKSGKWAWISVMVSELCFGLYWIITQSVRWRILQQTPFKHTLSQRYDEENLPAVDIFVCTADPILEPPCMTINTVLSAMAYNYPANKLSVYLSDDGGSELTFYALLKASIFSKHWLPFCRRFNVEPMSPEAFFAAPNSSNNSTEYGQAWLSIKKLYEDMKNEIESAVARGRVPDNVRNQHKGFSEWNPKTTKQDHQPIVKIIIDGRDTNAVDEDRFQLPRVVYMAREKRPNYPHHFKAGAVNALIRVSSEISNAPFILNLDCDMYPNTANTIQEILCFFLDETKGHDIAYVQFPQSYNNITKNDHYANSYLVSSKFELAGICGYGAALFCGTGCFHRRESLSGAYLIDYKAKWDIKPKINDNRTINELNEASKALATCTYEEGTQWGKEKGLVYGIPVEDIATGLVISCRGWKSIYYNPERKAFVGIAPTTLDVACLQHMRWSEGMFQVFFSKYCPFIYGHGKIHFGVQMGYCNYLLWAPMSLPTLCYVFVSPICLLRGIPLFPQLSSIWVLPFAYAFLATYGFSLCEYLICGSTAKGWWNLQRIKFIHRTTSYLFGFIDTMKKQLGLSQTKFVITDKVVTKDVQKRYEQEVIEFGGSSIMLTILATVALLNLFGLLWGMKRIMMDLEFSSSQLMMQITLSSLVVMISLPVYEALFIRSDKGCIPSSVMLKSIVLASLACFLAPFIC
The following text describes a protein:
Function:
Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.
Subcellular Localization:
Cytoplasm.
Sequence:
MADTTLSAQEELAAKEFIAAVNRARQQRGSGPLSWATAVKFLMARKFDVGRGLTLYEQHESTRIREGLVRFEPAAEPLRAELETGKFTVLPTRDGGGAAIAVFTARLHYPELSNHQVTLQGVVYQLDVALESVDTQRSGLVFIYDMSDSKYANFDYDLSQKILTLLKGAYPARLRKVLIVTAPLWFKAPFKILRLFVREKLRDRVYTVSLPQLTLHLPADSLPSELGGNLKVDHGAWLRYCFKSMTNRVGDLCDISTGPNPLFPPSETATTSEADDRPEGREDDEEEEPISEVSSDEDDDDVEEIEEPVPLQVESVAHRLEPIPLAPASQEFVNNFASVSCKTTSVVEGLPPPKPTVANVSDNMVIERSASPPPPPSSASSGFSDDDSLHFDDGRGMTLEEFAGHVKAKSKQGLYLEYADIKAKGTDGTFNNSRLKGNAAKNRYTDVLCYDHSRVVLSMEDSDDPCSDYINANYVDGYKQKNAFISTQGPLPKTYGDFWRMIWEQQCAVVVMTTRCLERGRPKCGQYWPLGEEESAEYGHFEIINLTTEQQSDYTISMLHLTNLKTRETRSVAHMQFTSWPDYGVPLSATAMLEFLQRMRDMQSGLVAAMGDTWIGHPLGPPIVVHCSAGIGRTGSLCTIDICLRRLEDVGTIDVLGTVEKIRSQRAHSIQMPDQYLFCHTAILECAVAAGLLQGDELACLDDEDDSSDGG
The following text describes a protein:
Function:
FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-polyprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid. Also acts downstream of coq4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-polyprenyl)phenol to 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to coq6 from NADPH via a ferredoxin/ferredoxin reductase system.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MQFSDASVRKEPPRHVIGNEVAENVLTSAEIGAWAHVNTARVQPYQEMQVWDGVTDARISFDWGTARSIGPRNPAQPTTIAYMIENINTTSMLLSRLEELGGVDMMTNTKVSSIELGTDTDKMDLSSWPILSLSNGKTLAARLLVGADGANSPVRTFAGIEARGFDYNRHGVVASLALEGPGWGGPQHKIAYQRFLPTGPIAMLPLPGNFSTLVWSTTPERAARLKALSQKDFVAMVNAGFRLSTTDLEYLHTLDAGQEEEVAWREKHTPVDGRAVPMRVTNVQAGTVASFPLRMRHADTYTGERVALVGDAAHTIHPLAGQGLNQGQGDAAALVRTISHAVQTGQDIGSTLALESYNSERYAENNAMLGVCDKLHRLYSVESGPIVGLRSLGLRAVDAMGPLKGFFMSRAAGGS
The following text describes a protein:
Function:
Participates in pre-mRNA splicing and in nuclear mRNA export. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
Sequence:
MDRNKRRLESSQLRESSSPNSQNKPNAMEEIKRRRLQLEQRLAQQAQVPWEKRSENGNNAGMETIQNRISELKEKTAKRFNANIPKSEGLFRDDSNGAKGGLKVGIHPVLLDGNIQNTILTPENRKRTASFSTKGVSLSQHQLLKPPAITEQNPFLDTAPTPRLEDSPFYDPRTKESRKTRGSRNLHLNESGKFIEEANQARRQARLEDLKKRIALHSHKAGIEDELDITSKSIGRDTIPNIEWWDLPFIKDYNDYGDENNWLIDGPQSIINSAIQHPIPVLPPYAKNQPSSHSVFLTKKEQKKIRRQTRAEARKEKQDRQLLGIEPPEPPKVKLSNLMHVLGDDAIKDPTKIEAEVRKQVEERRLRHERENEERKLTPEERKEKAFRKKDEDSAAGLRCLVFRIKYLAHRPHRLKIDLNAKQWGATGVCILNANFNLVIFEAGQKAIKKLKRLMLERIDWTDTSRNSIIAQGNKLVDTEGRELNYTENTCNLVWEGEIGRRAFRYWSFRSCPSENDAKSYLEEQGGAEHFWMLAKSWSENV
The following text describes a protein:
Function:
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MMGGMSVVEWLLLGSTTLALLFQSFATFSVPLSNGVTLSHFNGYKFGVFGWCDTTHTHCTPLKLGYSAEDGFLFAGQDELSLPTQAKYSLSKLLVVHPLALCSMVVLWLMVVLSQCYKHSDRRLTIIILWSFLTYMETLLCFLVDVLLFVPYLDWPGWLMLVSAVLVVFSSSIACLRRRTLTSQRIEKGAKEDLELYPLYGGALGAGVVSDSESPHRPYTEGSIISVTSRASSRLLPSASELETPREELTLMDPSIKCHIERSPMS
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MGLESSEFGFLLIVLAIVLASSQSEEGFGYQDNSLGPGQWGCLATNFSTCRTGTQQSPINIKTRDAIDDCSLGKLRFHFSHSAGTLTSQKYLYRIGLDGDAENTVIIDGMEFRLVQFHFHHPSEHFIDGKKFELEAHLVYRAMDNSSRMAVVAQMYKKGEENSLLAQVLDMKNNVRTLLDLREFNLGQEYFRYIGSLTTPPCTQGVTWTILIKNKTASKQQIKDLKQCLGGRNARPLQRTNRREVYMYTFYQNFLAKY
The following text describes a protein:
Function:
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Subcellular Localization:
Mitochondrion.
Sequence:
MKLIKQFCSFVGKEIDIKQASLINIVRSEIAEKGAISFPRFWHQALLHEKFGYYMKQDVFNKDGDFVTSVEISQMFNELIGIWLLNTFQHIGVLDNNFRPTNQKMHILEFGPGLGTLSSNVLRVFAQFNLLENLQYSYVEYSDYMRKKQQEAVLKQLQKSNIYPKFEYNNQKVEKFESDEVNLKWFKMYEHFLYEETREGQHCDPVLILAHEFFDALPVNVFEYSNGQWCERLVGLDNDGKTLKFVLSDGPNQNYFSSEIKKLIKEGDTIEISPQSGVIANSLAELISKVGGAALIIDYGEKRAFSDSVRAIQRHKLMDKKDILNKPGDCDLSAYVNFMALEQAALKVDGIKVPEIMTQGNWLEQMGIQARLQILCKNANKATEKRLQSEYERLVHSNQMGSNFKFMCIHRTKNNNLFPFIQDAQQIYY
The following text describes a protein:
Function:
Exhibits transcriptional activation activity. Positive regulator of light-regulated genes, probably being a direct downstream target of COP1 for mediating light control of gene expression.
Subcellular Localization:
Nucleus.
Sequence:
MDPRTRLDYALFQLTPTRTRCDLVIFSGGENEKLASGIFQPFVTHLKSVSDQISKGGYSVTLRPSSVGVPWFTKVTLQRFVRFVTTPEVLERSVTLEKEIEQIEDSIQANAAAIAGEAEGNELGGTWTSQKSTALSKTKGETDGDTVEENSKVGLQRVLENRKAALCKEQAMAYARALVVGFELDYMDDLFSFADAFGASRLREACVNFVDLCKRKNEDRMWVDQITAMQAFPRPELTFMGDSGIVLAGEENDLLNATNVKHGNSMDASSQGSFETGQEGRAQMAMPWPNQFPQYMQNFQGHGYPPPYMFPGMQGQSPYFHGNMQWPVNMGDVESNEKSSKKKKKKKKNKKKSKQDESAEPSDNSSTETESEDGNEGKKQSRKVVIRNINYITSKRNGAKESDSDESGEEEGFVDGDSIKQQVEEAIGSVERRHKSTSHRQRKHKSHNGDDDSSNKETKGNDNWDAFQNLLLKDNDSEPEELLRISSTALNMASEVVRKREPPSDDSFLVAIGNEDWGRETSIEKFNAGENVRIIRKGNNYDEEMLNPGRSDESRSYSQAEMSVHDGKLRTRNEAEEDWFIRNQAGPETDPSLVKTFVGDHFHLNKSSERDVLTDDSFMIHSRVENQVEDSRLRTEIMDLDVYGTTQQENSAPENTPHEPDDLYMVLGREQDVKPTLLPWTPEIDFETNTLAQRTSRIDLITATKASAGEQTLDGKEKKSRGISKGKDAKSRASSRPDPASKAKRPAWGSRAAVSKSKSEMEEERKKRMEELLIQRQKRIAEKSSGGSVSSSLASKKTPTVTKSVKSSIKNEKTPEAAQSKAKPVLRSSTIERLAVARTAPKEPQQKPVIKRTSKPSGYKTEKAQEKKSSKIGQSDAKSVELSRDPSLEIKETVVEDSHSYLSEKQVDALPAVASVDDFKDIKELHSLPSEETARVKNRPNEIIAEKVQDQTKIDDQETVKNTSVSEDKQITTKHYSEDVGEVQASQEKPVSPKKSVTFSETNMEEKYYFSPAVSEIDISTPPATEADHSRKKWNSEETSPKATAKVFRKLLMFGRKK
The following text describes a protein:
Function:
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
Sequence:
MHGIKRSRLTPQAAEAKRLKEQSKIETYLALEKDVLTRKSAKEYSEEALGKTTQLLDLNPEFYTIWNYRRDILLSLFPALTAEEVVGRLTTDLRLTTAYLLVHPKVYWIWNHRKWCLETVPSGPGKSHEWKAKFWDGELKLVEKMLDADPRNFHAWGYRRYVLSSMPVQRPLTEELNYTQSKIESNFSNFSAWHYRTKTLAAIWEENNSSPEDIKKAKDKEFELVTQALWTDPGDQSGWLYHSWLIGQKPPIDVLQRELKNIQELYDMEPDSKWCINALAQYTLLLAKQPSIAPEEAYKLRKDAKELYEILIEVDVDRKERYRDMAASCT
The following text describes a protein:
Function:
Hydroxycinnamoyl transferase that catalyzes the transfer of an acyl from p-coumaryol-CoA to various acyl acceptors. Can use feruloyl-CoA and caffeoyl-CoA as acyl donors.
Sequence:
MAITVRRSTMVRPAWETPRVRLWNSNLDLVVPRFHTPSVYFYRRGPEGGGAPEGFFDGERMRRALAEALVPFYPMAGRLARDEDGRVEIDCNGEGVLFVEADAPDASVDDYGDFAPTMELKRLIPAVDYTDDISSFSLLVLQVTYFKCGGVSLGVGMQHHVADGMSGLHFINSWSDLCRGTQIAIMPFIDRTLLRARDPPTPSYPHVEYQPAPAMLSSVPQSVTANKTTPPPTAVDIFKLTRSDLGRLRSQLPSGEGAPRFSTYAVLAAHVWRCVSLARGLPSEQPTKLYCATDGRQRLQPPLPEGYFGNVIFTATPLAEAGKVTSGLADGAAVIQEALDRMNDSYCRSALDYLELQPDLSALVRGAHTFRCPNLGLTSWVRLPIHDADFGWGRPVFMGPGGIAYEGLAFVLPSANKDGSLSIAISLQAEHMEKFRKLIFEV
The following text describes a protein:
Function:
Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
Sequence:
MSDQCVTVEAPINIAFIKYWGKREGGETLILPTNDSFSITLSASPFRSKTSVELRDDIETDTLRLNGTEVDVGKTPRVQSMLLHLRSTCPEDLKNKKVNIVSENNFPTAAGMASSASGYCAMSAALIRAFKSTTNVSMLARLGSGSACRSAFGGFVIWNKGEKPDGSDCVATQFVDETHWPEIQVMCAVLKGAQKDVSSTKGMQQSLKTSPLMKKRISETVPERMKIASRAIKARDFATFAEIAMLESDDLQEICATTEPKITYATEDSYAMIRLVKAYNAKKGRTALAYTFDAGANCFLFVLKEDLPEAVAMLMEHFPTPFEKFFFGDRELLEKVKVVSLPDEYKKLIDHPKKPFEMLLQSPVGCGVKYLGPSESLIPPRV
The following text describes a protein:
Function:
Membrane receptor which tethers secreted RH5 to the merozoite membrane during merozoite invasion of host erythocytes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MKIPFFILHILLLQFLLCLIRCYVHNDVIKFGEENSLKCSQGNLYVLHCEVQCLNGNNEIIHKRCNDDIEKKCNGNNKCIYFFEYELRKKTQSFRNKNSIEISECVESEQNEVKTSTTCLLSNSFILDEAFIQYFFFIKNKNEEPVICKDGNINIKSALLHSPFCEIKLKDISEYIRKKCDNNKECLIDPLDVQKNLLNEEDPCYINNSYVSVNVVCNKEEEIGDESTDSSSMEIQDSTSNEQDENVKGMSSSQEMNSNNDENKNQDNESDDDVNNNNNNNNDDQDEQGNDGDVTSSMNKNEDNKDLEHGSSNDVNNNTDTLVNNKENKEFVLKEKSSLTSKINKELAHRTALFNKLADNISLLLNKKYDSFEIKDVLEDRYNEMKRDANPDVYYIYLMDTLDIEKIEDINLEEVKMSLLASLKETMNKIDTIEKKIEEFKNKYISLYNKVKTTMPELFDLNEDLVLLYNDFPFDNGMISSDIFFKYNPSENIMDHQEMVKKGSITEDELRIVNDLEPLDNYRRRKRITELRKILVEKLRILYLEKNNLFNTQASCIKSYCYKNPLNLKTLEVLLKKNYYRLKENKDYDVVSSIIQHLDNVDANKKKKWLTHERILKKLQVLIAEGYKRINEKEKDIDRRMAVYNALYEKAQSYNLQKLFNDSNDFLKKYAIMGNSFDDGDEVFGSQSSNFNIFDSNNTDQNNEQEQPKQDDQLLNNNNDDVLSESNNENKEKTSDDATHKETQEKSDQEPSQNIQEDNSDEKHAENEENVEQIETDSNVSEEANDENKDNMQTTTDEGTEELQQNDEDAESLTKENSKSEEQENEDSTDAEAIDKEEVETEEKGKDEQKKDEQKEQDEEEDGEKENKHKSSETTNETVTDIEENKNEVKGEEHLQGSEQSIEASESSQKDETKETEDKEEYVNANDDESSEEDTTPNETNKTDNGSSFFFAMSNALLVILLLLFIEFL
The following text describes a protein:
Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MPQMAPISWLLLFIIFSITFILFCSINYYSYMPNSPKSNELKNINLNSMNWKW
The following text describes a protein:
Function:
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation.
Subcellular Localization:
Cytoplasm.
Sequence:
MEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPAGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELAELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQFWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQDCDGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTLLGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGEAFPLERDEVMPPPLQHPPTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTDTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVNELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRTHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ