lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the plastidial phosphorylated pathway of serine biosynthesis (PPSB).
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MATSLNLSSIFSSSSRLVTTPSSVFPIRQRRRIILVTSSSSGGGGKPTILVTEKLGQAGIDLLKKYANVDCSYDLSLEELCTKISLCDALIVRSGTKVGRDVFESSRGRLKVVGRAGVGIDNVDLAAATEYGCLVVNAPTANTVAAAEHGIALLTAMARNIAQADASIKAGKWTRNKYVGVSLVGKTLAVLGFGKVGSEVARRARGLGMHVITHDPYAPADRARAIGVELVSFEVAISTADFISLHLPLTAATSKMMNDVTFAMMKKGVRIVNVARGGVIDEEALLRALDSGIVAQAALDVFTVEPPVKDNKLVLHESVTATPHLGASTMEAQEGVSIEVAEAVIGALRGELAATAVNAPMVPLEVLRELKPYVVLAEKLGRLAVQLVTGGSGVNAVKVTYASSRAPDDLDTRLLRAMVIKGIIEPISSVFINLVNSDYIAKQRGVKISEERMVLDGSPENPIEYITVRIANVESRFASALSESGEIKVEGRVKQGVPSLTKVGLFGVDVSLEGSVILCRQVDQPGMIGKVASILGDENVNVSFMSVGRIAPGKQAVMAIGVDEQPSKETLKKIGDIPAIEEFVFLKL
The following text describes a protein:
Function:
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Sequence:
MRHDRTWGSSKMVTFDFAYNNPVFSDRVLHMDVAPVGNEFYEAVGKSEEQHIEKLYVSSVILAAHSDYFMRMFSNGMSESSSENAVVHVNEEEKFGLQQLIQYMYTGRLSEPLDIEATVMLLRLADRFAISSCMEPLAKILKLFPNTLSDCLLVLSLPESLKADRSVQPVVEHYRSYLASQFQDISSKKGDFLTLSIEGVKVILDSDALMVSYEEEVFQILLDWVDSNCRTAEEKQRAAEEVAGVIRFPWMTGDFLIDVVSTNPQMQTAACQALLMEALRFKSFTHARQQQMLWKKTNHNRYRPRNNTILENFWGNSKTFQVKQPDGSCQVLFEFPLELVICIGQSFQSRTFRLCDKYEFYLEARHGQVKTSYNQQLTCFVNLVLPPRNDSVSSCEEVEDLKFVDYTIAMKRDYSQNYDTKTSGSFCLTGVESAGACIPFTDFFSGWGIERGFNVPRWNLTINGPVFLKLDLKLRVEAFATDLDGQLQRRDESSSLATSHFEFPPLGPGTTDAIPF
The following text describes a protein:
Function:
Catalyzes the cleavage of thioester bonds from S-palmitoyl-CoA or S-palmitoyl-N-acetylcysteamine (unbranched structures) but does not have activity against palmitoylcysteine or palmitoylated proteins, branched structures or bulky head groups. Conversely, hydrolyzes both long and short chain fatty acyl-CoA substrate.
Subcellular Localization:
Lysosome.
Sequence:
MTGSASMEIIKGRIEEQHPGTIIYNTNRFSGWSSLENMWYQVQQLGQDLLNVSSQHPEGIHLLGYSQGALLSRTILQTFNNHNVHNFISLSGPQAGQYGTNFLHLIFPDLALKSAFELFYSRVGQHTSVGNYWNDPYHQTLYKEYSQYLPFVNNEIISNRSEEFKKGITKLNAMVLIGGPDDNVITPWESSQFGYFGQNDTVVNLIDRDIYKDDLIGLKTLDKAGKLKIITVPGVNHFMWHLNTSIVDNYILPYLD
The following text describes a protein:
Function:
Appears to modulate the timing of budding to obtain an appropriate cell size independent of the DNA replication cycle. Transcription factor involved in both heat resistance and flocculation.
Miscellaneous:
MISCELLANEOUS: Present with 937 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MRFRSSSHSLKHVDRELKELINSSENANKCGECGNFYPTWCSVNLGVFLCGRCASVHRKVFGSRDDDAFSNVKSLSMDRWTREDIDELVSLGGNKGNARFWNPKNVPFPFDGDDDKAIVEHYIRDKYILGKFRYDEIKPEDFGSRMDDFDGESDRFDERNRSRSRSRSHSFYKGGHNRSDYGGSRDSFQSSGSRYSRQLAELKDMGFGDTNKNLDALSSAHGNINRAIDYLEKSSSSRNSVSAAATTSTPPLPRRRATTSGPQPAIFDGTNVITPDFTSNSASFVQAKPAVFDGTLQQYYDPATGMIYVDQQQYAMAMQQQQQQQQQLAVAQAQAQAQAQAQAQVQAQAQAQAQAQAQAQQIQMQQLQMQQQQQAPLSFQQMSQGGNLPQGYFYTQ
The following text describes a protein:
Function:
Required for lin-12 degradation after it has been internalised in the vulval precursor cells.
Sequence:
MATFGFLSAPLKSTNEVDLVKPLTSYIDNVYNTSDNNRSDVAEAVQELNKLRSKACCQPLDKHQSALDVLTRYYDQLVAIENKIIISATQNPVVFKWKDAFDKGSLFSSRASLSLSDGSFERAAVLFNIGSLMSQIGAAQQFHTDDEIKVSAKLFQQSAGVFARLRDVVLGMVQQEPTPDLMPDTLAALSALMTAQAQEAIYIKGHKDKMKATSMVKISAQVAEFYSEAQKMMSKDIVRGLWDKDWSAIVSGKNLAYQALAQYHQSEVCGEARQIGEQLSRLAESLKLFDTAQKYLPRDITGIWDIYPSVSKAHAAAKKDNDFIYHEKVSDFRTLPTLPKAVLAKPTPMQTPMTPSFRDMFAVLVPVQVHNAMQSYDARKAELVNMETVRMREATQLMNGVLASLNLPAALDDVTSTETLPESLKLKSAKLKQNGGSSEIMRLFSELPTLYQRNEDILTETSRILNEEKESDDTMRKQLGTKWTRMSSEQLTGPLVTEIGKYRGILHTASNADKMVKEKFESHRQGIELLSKNESELRSSIPGQTAHATGETDTVRQLRQFMSQWNEVTTDRELLEKELKNTNCDIANDFLKAMAENQLINEEHISKEKIAQIFGDLKRRVQSSLDTQETLMNQIQAANNTFTGEKTGSSTGAERERILKMLAQASDAYVELKANLEEGTKFYNDLTPILVRLQQKVSDFAFARQTEKEDLMRQLQLSIVSGQAAKAVVDGVNSLVSSYLTGGTNAAQSPANAPPRPPPPRPAAPSVESPIPPPRTQQSMQATPGAPPQYNPYQQQQQPQMQQFQQHPGYYQQPMPYGQPQPMFQPQYQPTFAAPYPTFPGAFPSYQQQWPQQQQQGGFPPNPQFGQQNQQQGGGGGANPFQ
The following text describes a protein:
Function:
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis. Also involved in assembly of the spliceosome (By similarity).
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle. Note=Cell periphery. The polarization of EXO84 requires actin cables (By similarity).
Sequence:
MDNLDPNSSLQVEKLRNRKSRAVWQNNNTTTHNNPYANLSTGEKSRSRHNTGSSYVSPYGGGNGEENAYTGNNNKSNTSGNLLQVPGAGGGGDLNSNKKQSRRMSIHVSARQHGRSFSQTGPIDMANLPALPKIGGVTTSGVGGAGGDVMTRTGGLTIEQKIFKELSQGSAAEVDDYYKTLLKQKNLITRDIKDNINQNQKNILQLTKDLKETQEELIELRGTTKELYEVLGYFKESAQRRLELEFEPETQKELHSPQKSNQLGIPSNKKKDRSSIMVLKKMWDSQLQSLFKHVDGASKFVQPLPNRHIVAESGRWFEVNVGNWKPSYPTHLFIFNDLILIAVKKSSSSSQEPTTGGSNGGSKSRLQAVQCWPLTQVSLQQIKSPKKDDDKMYFINLKSKSLSYVYSTDRYDHFVKVTEAFNKGRNEMIQSERLLDSRLSSPSNNNGDSKEEKRQLRESLRNSGNYKEGVTDDAGGAATGGGRKSAGTPNRNSTDYVLHDISARVHSRNRSQDLGNNFKLANNGKSQFFNEIKTLEDRLDDVDVEISHNQYAEAVELISIIESKLRNIENALTNQRNGGKNVNIADELLLLDVSKLKIKNRKENVSNGLIFDLQHNIAKLKQDDIDNILTLFDNLEQLDRGVQGYLDSMSAYLSTTVSKLIVGLQGSTKIDVVNYLSNLMVINVSIVKRTIQTYEQIIAPILKRHGDVDSSGLINWCIDEFTKLCKQIKKHLYGTLLISSGINMETDEPIYKVKERKLYDNFLKIMQPQLEELKSVGLNVDYIFESILNLE
The following text describes a protein:
Function:
Two-heme-containing cytochrome. Catalyzes ascorbate-dependent trans-membrane electron transfer by utilizing a concerted H(+)/e(-) transfer mechanism.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAIIGNYHHSVIASRVAMFAHLVFLVTAVLMLVWLLRFRGGINIQSDDPDQIFNVHPFVMTWGFILLIGEAILAYTTVPMNHRAQKVVHMLVHLVAFILGVFGIYAAFKFHDAAVAPDLVSLHSWLGIAAISLFGLQWLVGFAVFWMPGTHEHARAAAAPAHVMGGLAVFLLAVCAAQTGLVQKGAAAAPGTEARLINVTGVFILLYGVAVASAVALRKAFL
The following text describes a protein:
Function:
Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction.
Subcellular Localization:
Early endosome. Secreted.
Sequence:
MDFVDVNESNTRWIQDFRLKSYASPAKLESIDGARYHAVLIPNCPGAPVDLANSGYLARILQHFSAESSPICRHRPRCRCLVAAPRKKTSPGCSRDYSMTGPSVYELIRQPGFASLPIILGGLRQRLGGHLQRQPAGRRARGAGPPPRHGPERQLHRRRRAEPGLPLRCQEMRTSPRPATGSEGPREAAGRAPRPGGASSGSRPLPGPSAPGRRGPGGIRAVRWSPLGGEPFSPVLTLTPPLHPVPPSPGGRVEPQKAGAGRRLSPGDVAEGPLGLRLKRTTDAHPPHRLSPGPLPPGCGFLVKRKARSSLGALRAGLSVCVGARAARPAVWEGTERVCECVLGWGRGGGCPLCVCVGGVGERGRERVFVCVGIGDRKSGPNCL
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Subcellular Localization:
Cytoplasm.
Sequence:
MNIVVLGPGAVGSLWALHLHSAGHQVALWSRQAQPTITLQLDEEAPISFRNQNLDTLIHADLLLITVKAWQVEAALQPLLPHLNRETILLFMHNGMGAVEAISESLTHFPVLFATTTHGALKATLNQVSHTGFGQTQVGPFNALGARCDFIADVFNHALAPVTWNPEIQQALWRKLAVNCAINPLTAIHQCANGALVAPEFTPIITAILDEVTAVMQAEAISGEAEALRDGVYQVIQATAANLSSMHQDVFHRRPTEIDFITGYVVRKGEQHGIATPVNSALYQQIKTLEQSWSKA
The following text describes a protein:
Function:
Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
Sequence:
MFNKVIMVGRLTRNVELKYLPSGSAAATIGLATSRRFKKQDGTLGEEVCFIDARLFGRTAEIANQYLSKGSSVLIEGRLTYESWMDQTGKKNSRHTITADSLQFMDKKSDNPQANAMQDSIMHENSNNAYPANHNAPSQDPFNQAYAQNAYAKENLQAQPSKYQNSVPEINIDEEEIPF
The following text describes a protein:
Function:
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). May play a role in intracellular vesicle trafficking (By similarity).
Sequence:
MAGEKMVRDISGVYARLFDHRAVLQAECKYMLREFEGKRNDRELERLRESEQKIRQVQEEIPKCITESVKLKDLLEELKVAREKCHEILVKEEQDLFKERREEIFIESKKNWETFIGEIAEEEKRIEEEFEQSAEKLRARYGVQLVRNPKEPDDKGELQPQEIA
The following text describes a protein:
Function:
Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MGVPSFFAWLTKKYVSITNDCKKNSSIENDDLLSPNPNGVEYDNFYIDLNGLIHPCYHPTDRQTPETNVDVFVLLTRYIDYMVDIVRPRKLLYIAIDGVAPRAKMNQQRSRRFKTAQNMVNQSFEEKKSVFKEKPIDSNCITPGTEFMEAVSKVIKAYIKERMNSSKYWNSIIVIFSDSSVPGEGEHKIIDFIRRQKDCKNYNPYIRHCMYGLDADLIMLALATHERYFSIIRDKPYNKGDKCYICGEYHSSDSCKNYNRVAPLDPITKPFIFVDCHVLRQYLNNTIKVEKYDFERCLDDFIFFCFLVGNDFLPHIPSLDIQEGAIDILIKIYLKFLPENGYITENGTINFKIVKRFLHLVGKEEKQLLVNRRLRKEKEDQLYFDKKMRELDYQIQSAFENRTEALPQRKTEIKVKSIKEVELAKEESQLIRESLEKKKQEVVRQMEELKHDEIQLGEQGYEERYYQQKFHVDYKKEKNNIIEIVDSYVEGLNWVFSYYYEGCQSWDWYYPYYYAPFAKDIGKLLDPEFEVQYTQGKPFRPFEQLMSVLPPQSKHCLPKEFQQLMNSTSSPLSSFYPEDFKIDMNGERSFYKAIALIGFINQKKLLNVVEPIEKELGKKDQQRNSRYGNTFIFIGKSNWYYRKDIHHFKKIGKEAWKQLKKEIKTYISNDQVVPIKTYKPLHIESNYTKHQFGGLIIPIRGMDLGKDKSKCYMLGYIPPQYKNGHIFKTRYIGEPLESPQELDSMKAKSQPLRKSIKRQRDIREYRLVPLTPDNSEKKK
The following text describes a protein:
Function:
Hydrolase highly specific for thiamine triphosphate (ThTP).
Subcellular Localization:
Cytoplasm.
Sequence:
MAAVLEVELKFRAAAQVLARVKALALHASQPRLFVDRYFDVPDEYTLSRSDHWLRQRWSLGESASWELKSPPSRLPTPTEGTASAVDCYEERTGLAALQKAARLLGVPAPEAPTAAPASVWPYGLLLTERTRFTLPPPQREATDGNSALPVTEFGVDIDRVWFCQDQQVAWSDSDLLELTQSAAPDYAVGEVEIMLPGDGGVVSEQALLASAEAKQLLRAFVAEQLEGDPDEGVPGKVLEYLRRYQPDHLRVLVSCGLIGQKLGADPTSA
The following text describes a protein:
Function:
Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
Subcellular Localization:
Cell inner membrane; Lipid-anchor; Periplasmic side.
Sequence:
MAERFRPLAMAGLAALALVLAGCGDTLESFGGPTMGSTYSIKYVRGASAPDVQTAKAAVEAILAEVDRQMSTYRDDSLVSRFNALPAQSCMELPLPMLELLRYGGELSEQSQGAFDMTVEPLMNLWGFGPQARVEKVPSAEQIAAVRRDVGHRHLRIDGQRLCKDAAVQLDFDSIAAGYTVDAVGERLKELGVRSYLAEITGELKAEGRKPDGTPWRIAIEAPREGQRVAQQVLALDGYGVSTSGDYRNYFEENGQRYSHTFDPRTGAPIDHHLASVTVIDPSTRNADGLSTLLMVLGPEEGYRFAEKHRLAALFVSRQGNGFDSRTTPRYEQLFGNQGERP
The following text describes a protein:
Function:
Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPases.
Sequence:
MADGSPRPPLYRSVSFKLLERWSGGPGPREEDADTPGLRRRASCRPAAAVPGQPSRRVSKLASGPPAAPAQPRPLRSLSPSVRQLSRRFDAAGLDDDSTGTRDGGCSSGTTEEAAEGSERGAWPSVTEMRKLFGGPSSRRPSMDSEALGSTSPDRVSWEPPTRDPRQPPTPPPRTCFPLAGLRSARPLSGPGIEGRRRRQHQQQERAQRPADGLHSWHSFSQPQAGARASSSSSIASSYPVSRSRAASSSEEEEEGPQSQLGPQSPAYLGGHSSGSDEDPNGEDGRRWRGRGLRPGRSQLVHGCSQDSDELNPGGLGSAGGVGSPEPPTSPRTSMDEWGTGTQPCLPGPQESLRPMSDTGGAPFRVAKVSFPAYLASPAGSRGSSRYSSTETLKDDDLWSSRSSVGWGVYRSPSFGTGDGLLLRPQTRSRSKGPVGTARPLRDGGLDLDKNRQRKSLSNPDIASETLTLLSFLRSDLSELRVRKPSGGPGNRPLDGRDSPSAGSPMEQSESTLSQSPTSPTTRPTLKDLTATLRRAKSFSCSEKPMARRLLRTSALKPSSSELLLAGSGAEEDPLPLVVQDQYVQEARQVFEKIQRMGAQQDDGNDVCPTSPDWAGDMTQGHRSQEELSGPESNLTDEGIGADPEPLGAAFCSLDPAGVWRPLSSTSAQTNHHLGAGTEDSLGGRALVSPETPPTPGALRRRRKVPPSGPNGTELSNGEASEAYRSLSDPIPQRHRAATSEEPSGFSVDSNLLGSLNSKTGLPVTPAMDEGLTSGHSDWSVVSEENKDYQEVIQSIVQGPGALGRMGEDRIAGKTPKKKSLSDPSRRGELTGPGFEGPGGEPIREVEPMLPPSSSEPILAEQWTEPEDPAPARGRAQSERSLPAPPASSTAHHDFHLDPKLTSVLSPRLTRRGSKKRPARSSHQELRREEGNQDQTGSLTQTRSSSKHVRHASVPATFTPIVVPEPAMSVGPPVAAPEPVGFPVRGHPALQAPSLEDVTKRYMLTLHSGDVPAPGPVDLPCLPPSAPPSTETKPSGAARATPDEPAPASKCCSKPQVDMRKHVTMTLLDTEQSYVESLRTLMQGYMQPLKQPENSLLCDPSLVDEIFDQIPELLEHHEQFLEQVRHCVQTWHAQQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPDHPLLLDAQRNIKQVAERINKGVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDTDIIKGASQATNRETIQKAISRLDEDLATLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCCSLAFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTFSSCPEPAPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGAVPGLQPRCPREQPEPLRNPPETTLESTGPELDVEATAEEEAATTLAEPGPQPCLHISISGSGLEMEPGPAKGDPQPELVPFDSDSDDESSPSPSGTLQSQASQSTISSSFGNEETPSSKEATAETTSSEEEQEPGFLSLSGSFGPGGPCGTSPMDGRALRRSSRGSFTRGSLEDLLSVDPEAYQSSVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNKVFVSLANGELVVYQREAGRFWDPQNFKSMTLGSQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHTFYVGQDSSRSVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKAACLRITALLVCAELLWVGTSAGVVLTIPTSPSTVSCPRAPLSPAGLCQGHTGHVRFLAAVQLPEGFNLLCSTPPPPPDTGPEKLPSLDHRDSPRRRGPTSARPKMLVISGGDGSEDFRLSSGGGGSSETVGRDDSTNHLLLWRV
The following text describes a protein:
Function:
Major component of the cell cycle transcription factor complex MBF (MCB binding factor, also known as DSC1), that controls G1-S phase specific gene expression. Involved in the control of rRNA production, via interaction with pol5. May be involved in the transcriptional regulation of the cdc22 and cdt1 genes. In fission yeast, two genes, cdc10 and cdc2, are required for the cell cycle control called start, the point early in the G1 phase at which cells become committed to the mitotic cycle.
Subcellular Localization:
Nucleus.
Sequence:
MASANFIRQFELGNDSFSYQKRPEDEPSQPLSNRNINKLNDSSTLKDSSSRIFINSQVLRDGRPVELYAVECSGMKYMELSCGDNVALRRCPDSYFNISQILRLAGTSSSENAKELDDIIESGDYENVDSKHPQIDGVWVPYDRAISIAKRYGVYEILQPLISFNLDLFPKFSKQQQIESSSISKNLNTSSFNTRSPLRNHNFSNPSKSSKNGVHTINNMQSSPSPSSSFLLPLTQIDSQNVKRSNNYLSTSPPILEQRLKRHRIDVSDEDLHPSSQLNDNEASSLFPDTPRLNHSLSFVSLVSSLPPLDQNIMQDYHTSKDILTSIFLDVNFADSSALEAKLSDSLDLDVPIDELGHAALHWAAAVAKMPLLQALIHKGANPLRGNLTGETALMRSVLVTNHLNQNSFGDLLDLLYASLPCTDRAGRTVVHHICLTAGIKGRGSASRYYLETLLNWAKKHASGNNGYMLKDFINYLNHQDKNGDTALNIAARIGNKNIVEVLMQAGASAYIPNRAGLSVANFGIFVENALKQPEDSKQTKVSLMSENLSSKEKTAVPPRQKSRDIIASVTDVISSLDKDFQDEMAAKQSMIDSAYTQLRESTKKLSDLREQLHVSETQRTLFLELRQRCKNLMTSIEEQKSELSNLYESFDPNGIHDSLSLDADAPFTVNENNNKNLSIAELKFQVAAYERNEARLNELANKLWQRNSNIKSKCRRVVSLCTGVDESRVDSLLESLLQAVESDGQQGEVDMGRVAGFLRVVKEHQA
The following text describes a protein:
Function:
Polymerase that creates the 3'-poly(A) tail of mRNA's. May acquire specificity through interaction with a cleavage and polyadenylation factor.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MACELKEFLVKNDMYPMGDQVEKKRKAISKMTEYIQQWGKKIYIESAGVADDTDVKAATIYVYGSYRLNVYGNNSDIDACIVSNSTITRDDFYDGLYAELLNNPDVKELKQIPSKRSPHLSMIYLNIEFDLNFSRTAYTSLPDNLDILNENILKNMDELDTRAINGVRNTDIIDAFVPNHSEEAFRVMVRTIKLWTKKRGIYGYVYCFLNGISIEILVAQVISENYQLDNVRLLEKFFQVYSSWDWLRTPVMLGTNDDFNDKKKEGVIQILTPASPSENAAFSITKFSLEMIKRELKRGQEIVHEFSSEGVNDWAKLFKPRHLFCGYYIFIEFIVTSSSLEGLTTTIGKFESGLVNLMKGLSEIEEIIEANVIPNGFLDEENEKYFYYVGMNVKRDCPVDISTPLNSFLSIVNSGKDLIVDASIKKRSEIPTKFAHSVKRSITKSQEIKETSSQVPSSAITETFDIPTKPSIEQQLKAKEENSIPNEEKKEQLKKEMKQEANTIVKNSSTDDDFMKRFTRKN
The following text describes a protein:
Function:
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens. H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis. Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MWPPSRRQLCLAFLLVCVLSALSFFLHIHQDSFPHGLRLSILCPDRHLVTSPVAIFCLPGTPVGPNTSSSCPQNSASLSGTWTIYPDGRFGNQMGQYATLLALAQLNGRRAFILPAMHAALAPVFRITLPVLAPEVDSRTPWRELQLHDWMSEEYADLRDPFLKLSGFPCSWTFFHHLREQIRREFTLHDHLREEAQSVLGQLRLGLTGDRPRTFVGVHVRRGDYLQVMPQRWKGVVGDSAYLRQAMDWFRARHEAPVFVVTSNGMEWCKENIDTSQGDVTFAGDGQEATPWKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEFLKIFKPEAAFLPEWVGINADLSPLWTLAEP
The following text describes a protein:
Function:
Functions as a transcriptional repressor. Required for brain development.
Subcellular Localization:
Nucleus.
Sequence:
MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKDCESSHSEGKTEPPVLETQSTIPDTEKTQSIPSEVSTDLNLTLSEQSASESAPEDQTDREEEFKSTLDEAKVDKSPGVDGKALNCKRASPKSESPISATVTPSSSSGLAQTHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEMGTPSAMPYLGMNVNMAPLSSLHCQSYYQSLSHAQQVWSSPILQASSSLPSLNSKTTSIENLRLRAKQHAASLGLDTLPN
The following text describes a protein:
Function:
Probable transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MGRGKIVIRRIDNSTSRQVTFSKRRNGLLKKAKELAILCDAEVGLIIFSSTGKLYEFSNTSMKSVIERYNKTKDERQQLHNPVSELKLWQREAEILRQQLQDLQENHRQLMGEELCGLGVKDLTNLENQLEMSLRGIRMKKEQLLKDEIQELTQKGSMIHQENLELYKKVNLIRQENAELYKKAYGTRNANTVNGNTNSPYRFTVSREVHAPIHLQLSQPEPHNFEATAGVSNSR
The following text describes a protein:
Function:
Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
Subcellular Localization:
Preautophagosomal structure membrane; Multi-pass membrane protein.
Sequence:
MVRRMGWGGTRGRLGRWGDLGPGSVPLLPTPPPPLPPPPRRGPGVGRVSVFSLSPAPHARRAPSSAPPSAPGPPCPVAQAPGAPQLCHSALPTPAIPASQVQPETTPISAPPSWGSHSAPPLASVTPHPPRQCPQDPPGLRIGPLIPEQDYERLEDCDPEGSQESPLHGEEQQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRSGFACILLEDVFQLGQFVFIVTFTTFLLRCVDYNVLFANQPNNRTSPGLLHSKVTLSDAILPSSQCAQRIHSSPLLVFLLILAAAFWLFQLLRSVCNLCGYWDVQVFYREALHIPPEELSYVPWAEVQSRLLTLQRSGGLCVQPRPLTELDVHHRILRYTNYQVALANKGLLPARCPLPWGGTAAFLSRGLALNVDLLLFRGPFSLFRGGWELPDAYKRSDQRAALASRWRRTVLLLAAVNLALSPLVLAWQVLHAFYSHTELLRREPGALGTRRWSRLARLQLRHFNELPHELRARLARAYRPAAAFLRAAAPPAPLVALLARQLVFFAGALFAALLVLTVYDEDVLAVEHVLAAMTALGVLATVARSFIPDEQGQSRSPQLLLQAALAHMHYLPEETRPAERTGAYRQMARLLQYRAVSLMEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDVCSFALMDVKRHGHPQWLSEGQTEASLSQRAEDGKTELSLMRFSLVHPQWCPPGHSSKFLGHLRGRVQQDAAAWGASSVRSPPTPGVLSNSSSPLPEAFLANLLGQPLLPPQDLSPTGPSRAAATASLLASISRMAQDSSCVSPGGTGGQKLAQLPELASAEISLHAIYLHQLHQQQQQELWGEASASSLSRPWSSPSQTLSPDEEKPSWSSDGSSPASSPRQQWRTQRTQNLFPGGFQETTDTQKEPGQAASTD
The following text describes a protein:
Function:
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDSSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL
The following text describes a protein:
Function:
Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MDQGKVMRRLYVGGLNHTISQSELKQRFGKFGDVLDVDIVTRKDEEGTPVKTFGYLNITISEKELSKCMSLLNKTKWKGGTLQIELAKESFLHKLAQERQQAAQKKQTPKTERRPPFLDSLKKVGVDNFHMKAAVPGTEVPGHKNWVVSKFGRVLPVLNMKNQGKNKIVKYDPSKNCHNIKKLEQAIDFDNFTPVSKLTWELTGGDDDISKKRRGEFPLPKSRPKKMMKPASFSSGKEFADSDLEVIRNSQDHRLSGNVNNKQVKSPKVNQEAKPPLKPCSKEENFVGKKHSAALKAQNKSMNLFDSDVDSEDEIRKLVVQEDIRNASLVEEDVDNLEVVEGDFVLKPNFRQLQHPVKDGNKAKAVNTSGRCDSEHEYDSADTDEILTSCKTAAKSQKHLETSIIKTGVPDSLSVTAQKHPPSSKIPSSKRTKTTQSDNTVTFDFPPSSTESISSDEGSDQSCDSEYESMMANCCRFELSLADLEKIANESSRDVEEEIEDCQESDVEAKATGGSDLHINSKKKTPIKSSARRGITPEDILASLLNESSSEDEYDGDKKKKMKKQKSPLNLPAFKGTKTLEEAGMESGVCQKRKQEEGHLGAESLKKKKITETQEDKWKAATLEVKTTNSKPPPFKGVQHFLPKSEKTDSTALAQNMEERETEESDFDSSDSDGEDTITKPKASAKKLKGGESPVSSKAQPTPSRAWEGSSSSSSSSTSAPGEESSAEENDMGKAKARHSQNTTTEPTRRSCENLASLTNPIRSTEKADVVVSIKVDSKASWFSSSENALKQQQDNEKRLAALQQRQKEAEQQKRLIQGALSKLDTSETSKGKHIVFESEEESDEEAKETTLRKSLFAEREDSHGGNSSEEEDPGIKTNSDPTAKVKEFKKQVAGKLFENSEDEASSEDDNDDRFQIKPQFEGKAGQKLMALQSRFGTDERFRMDTRFLESDEQSDDSEEAKSGEEDELEEEKRKNMEILQNLLNINIHTPETVKETAKKKTFRDVNALHYDPTKEEHAALETKAENPQKESKAARRKKREEAEKLPEVSKEIYYKVAVDLKEVFGPQKEKGEEKRDVAWDKKEDETTAVDNSSGHIFNFSSSSGAGKEESTGFTFSFFGDDAANEPSVKEGDYKIELLKPAKVPWQEDPRFQESSSEEEDEGETGEKPVPDVTKEEPFPAKKTNLFFFFKDDERLKEGPKMFCRSVKLEQGREQWEADRGALIEEYKKRHKDAKRIVKVQQAARRNQGVLSTK
The following text describes a protein:
Function:
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.
Sequence:
MLHVRSIWNGAISFGLVSIPIKLVNATESHSVSFRQIHTEDGGRIRYRKVCELEDREVTQAEIGKAYEDADGSMIPITDEDLSQLPIPTARTIEIVAFVPEDRIDPLQMGSAYYLAASGAPAAKPYTLLREALKRSNRVAIAKFALRGRERLGMLRVVGDAIAMHGLLWPDEVRAPEGVAPEGGVTVRDQELDLADALMDTLGEIDLDDLHDEYREAVEEVVAAKASGEKPPEAREEAAPGKVLDLMAALESSVRAARESRDGEGAGPAEEAEVRSLSRRKTSSRAPKETGGKKSTSTAAKKTAAKRAEPKKSTAKAAGSAKKTAAGSPAKGTAKKATARSTARSGDKGAAKSTAKKTASRRRSA
The following text describes a protein:
Function:
Binds promoter DNA and regulates initiation of transcription (By similarity). Regulator of mitochondrial ribosome biogenesis and translation that is essential for development. Required for normal mitochondrial transcription and translation. Required for assembly of mitochondrial respiratory complexes and normal mitochondrial function. Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit.
Subcellular Localization:
Mitochondrion.
Sequence:
MFCSALRNILRNSQNAAKNATITSQIRNLRGQQSVHHEVEVLTSPGITTKQNDKKTEPAECEGSKEVALDFRNREAHVPSFNLAAYVNNSSTLQQFLSLGVDLHSIERRKGLGDFVLKLDFEKNVKPYITFLVDQGVSPDDFGRMFTKNPLLFKEDLDDLQTRVNYLKSKRFSDEARQRILTQNPYWLMFSTRRVDRRLGYFQKEFKLSGHDLRLLATREPNAITYNMEHLRKSVFTLKEEMGFNAKELSDLVVRKPRLLMIPPDDLVERFSYIHQDMGLPHAQIVQCPELLASREFRLRERHEFLKLLGRAQYDPQKDLYISPKTIVEGNNFYFVRNVAKSDLETFDLFLKTR