lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Repair polymerase involved in base excision repair (BER) and responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity (By similarity). Involved in the repair of transposon-induced DNA double strand breaks (DSBs). Involved in repair of UV-B-mediated DNA damage during seedling development through an excision repair mechanism. Involved the repair of DSBs induced by high salinity and DNA cross-linking agent. Functions via the DNA non-homologous end joining (NHEJ) pathway.
Subcellular Localization:
Nucleus.
Sequence:
MAAKRGRNRSPSPDPEGMFAGMVVFMVEIGVQRRRLQIWKQKLVQMGAVIEEDRVTKKVTHVLAMNLEALLHKFGKERLSHFTARLMLYQWLEDSLTSGEKANEDLYVLKIDSEEVDKPKKSLPAISGSEDQSSPQKRTRYSPDAGDFKGVESHSNTQGSPDSPTSCSVPSTSASPGEGIAETPTSPQSESTSVYKPPDLNRNITEIFGKLINIYRALGEDRRSFSYYKAIPVIEKFPTRIESVDQLKHLPGIGKAMRDHIQEIVTTGKLSKLEHFETDEKVRTISLFGEVWGVGPATALKLYEKGHRTLEDLKNEDSLTHAQKLGLKYFDDIKTRIPRQEVQEMEQLLQRVGEETLPGVNIVCGGSYRRGKATCGDLDIVVTHPDGQSHKGFLTKFVKRLKEMNFLREDLIFSTHSEEGTDSGVDTYFGLCTYPGQELRRRIDFKVYPRDIYSFGLIAWTGNDVLNRRLRLLAESKGYRLDDTGLFPATHSSSGNRGARGTASLKLSTEKQVFDFLGFPWLEPHERNL
The following text describes a protein:
Function:
Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MADYSTVPPPSSGSAGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWTSPSSTTHWEGMPSPFKDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQQGQTQDYSKAWEEYYKKQGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ
The following text describes a protein:
Function:
Cilium-specific protein required for cilia structures.
Subcellular Localization:
Cell projection, cilium.
Sequence:
MTKKTIQASCRKNKLYLTPHLNDVLYLHYSGYNAIDGLDEYVGLKCLWLECNAISNISGLDHQSQLRCLYLHNNLIKKIENLQHCKQLDTLNLSHNHIAKIENCGSDILPVLNTLNISHNYLKSIESLAELRKCDFVSVLDISHNRIEDIAIVKVLADMKGLRVLTLVGNPVVNDIPSYRKTLILECKSLTYLDSRPVFDKDRACAEAWKRGGYEEERKEHQRWKKEEQRKMRRSINATLRLRHRGDGEPELLKTSSDEEEEEKEGSAAGRGDFEELEYQSNDVAWKEMEALFNQHTKGDTQQAQKLAEERKASTNSVDYITGSDSNSDPTLVTDCDSCVRNSSRACSSRSDTSDSEDMFDKIVPKKHRKLASSMRPEVSLSDSSSSSSETEDEAGSILDSKLDRQNTITEFIDEYKRFFHSVDLRDPKCVLKNRHKIVRPQTAKSQRTEPIVYEGVLKAMEQNSNGAKIEQARQERFEANERSLAKEAVLERLMKGHAEVDMNIEQQMISIGGKQHNFNEYRLEVFRQDQEKLQNLIDRVTAQKEKYNAHIDSIHDQLANIMEDYGQISEKLRKVDDMIQNIGDEVVVHQEKERDGLEVIQELEPITIAEQIVENMTKEQVPDEVEANDKASDATIDPVDQLSSDESAIDLGELNQHVDAQVEVGPSDPKDATTSKPIPEEFGSDPVYRKFIDIQYEIDKLTEDQIFTALSEAARELQEEELETKLVHDAIDEYWSTDLEDFRRNLNLDAHPIVQRFKRFIECQGTDTDDTDSEAHVRRLENAYHRYERRLSNHLFDEYLMLSRKASIATTTGGESSATELELVELDGGHVLRASTSRRATAWDLKETVEDPVEELEELNEEEDPALKEAGDFKHDELEDEESKPEEKTLKSAEVLGMQEPLADVQGDH
The following text describes a protein:
Function:
Pseudouridylate synthase responsible for the pseudouridine-2819 formation in mitochondrial 21S rRNA. May modulate the efficiency or the fidelity of the mitochondrial translation machinery.
Subcellular Localization:
Mitochondrion.
Sequence:
MSLKKQIPIIFENTHYFIVNKPPGIPSQPPDCRTWGRTHPNLDPTPLLERFKAIYYSHREVELCRTVHRLDHCVTGGMLIAKTKDGSVKFSRFLQKGGNNGYKLQRKYVAIVESSGRFNKPNNYEIKYGPKYNFLISHGGREITKFKEVDENCIVLQLVTGKKHQIRNHVSQILNQPILNDKRHGSTVNFPELFNDQIALHSACIITKIGLQTKTHLIPMEHNNTGQLWSRKYVNEEGEFTLPIKEVLLENWDQ
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
Subcellular Localization:
Nucleus.
Sequence:
MSVPIRADVVGGKKKSSSRGHHRFVGVRQRPSGRWVAEIKDSLQKVRLWLGTFDTAEEAARAYDDAARALRGANARTNFELAGPQLASSSSTNRFSFDKLQPFSFEEACGKGGSDDGDGFIGALKAKLLDRKGLKVLSLANPAVVPPPQRIGNMNLVQGPTSKPDGEVAVGHIEAQWYQPVQSQTPSMTSKIWSNEPSFEAATWGAQMNQVPPNGLFDISTLTAATSTWSLPGTAVSTMDLSFPNQCQIELPVNMPISQINGTTTESVWSSEQQFLQCDIDTLSGPIGSWGDPYLYVSSVLG
The following text describes a protein:
Function:
Catalyzes methyl transfer from S-methylmethionine (SMM) to adenosyl-L-homocysteine (AdoMet). SMM degradation (by HMT-1, HMT-2, HMT-3 and HMT-4) and biosynthesis (by MMT1) constitute the SMM cycle in plants, which is probably required to achieve short term control of AdoMet level.
Sequence:
MAGVVEELVKKAGGCAVIDGGFATQLEALGADINDPLWSAACLITKPHLIKEVHMQYLEAGADVIISSSYQATIPGFLARGLLLEEAEGLLRTSVQLAREARDEFWKSTLRSSKPVYNRALVAASIGSYGAYLADGSEYSGSYGDDVTAEKLKDFHRRRLQVLASAGPDLIAFEAIPNKMEAQALVELLEEEDIQVPSWICFSSVDGKHLCSGESFGDCLQILNASEKVAIVGVNCTPPQFVEGIIRDFKKQTKKAIAVYPNSGEVWDGRAKRWLPVECFGRKSFDVMARRWQEAGASLVGGCCRTTPSTIRAVSNALKSRNGQ
The following text describes a protein:
Function:
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
Subcellular Localization:
Nucleus.
Sequence:
MGDEGKKEKRRQTKEDAVYGFVFESDSNSDDSGGSRRKKRRKTKPVKFSSAGNIDQVLKQNRGNCKIDENDDTILPIALGKKIADKAHVREKNNKKENFEKFSGGIGMKLLEKMGYKGRGLGKNQQGIVAPIEVQLRPKNMGMGYNDFKEKNAPLFPCLNKVEEKKKSVVVTVSENHGDGRRDLWKKKNVRKEVYITAEEFLGKKQEEGFGCDQLIIDKRGPQDRVVNSLRNLYAEEKATDANVQQPELQHNLRFIVKSLEHGILKTDKDLRNEKGLALSLQQEKEKFKMGVKKQKTLFDNLGYVAEEIDRIEVEIASGNLTLDSLANRFKDLRSSYPDDYKCCNLSCIASSLALPLFIRMFQGWDPLSDAEHGIEAISSWKMLLEVEDNQSISTPYSQLVSEVILPAVRVSGINTWEPRDPEPMLRLLETWEKMLPSLIFETILTTVVLPKLSIAIESWEPRLETVPIHFWVHPWLPVLGQKLESAYQIIRMKFGNLLDAWHPSDVSVHTILSPWKTVFDAASWEQLMRRYIVPKLQVALQEFQINPADQNLDEFNLVMGWVSSVPIHLMTDLMERFFFPKWLDVLYHWLCSEPKFDEIMKWFLGWKGTFPQELSANRRIEIQFKRGLDMAREAVERMEMSQPGARENISYHKAQEQRQSEGRAKVQAQVDDPEELSFKEAVELFAQEKELLLKPKPHRMHNGLQIYRFGNVSVLLDSANSKLLAQEEGRWFPVDLDSLLKMHYSAVTGKQ
The following text describes a protein:
Function:
Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.
Sequence:
MNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
The following text describes a protein:
Function:
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MAMRGDPKQRRASASAPHGGAAHHVADKLRRHSTFLLLLLLLWFALSLYLFLSATPPPPRPAFLPSTSTPRPALRIYVYDLPARFNRHWVAADARCATHLFAAEVALHEALLAYAGRAARPDDATLFFVPVYVSCNFSTDNGFPSLSHARALLADAVDLVRAQMPYWNRSAGADHVFVASHDFGACFHPMEDVAIADGIPEFLKRSILLQTFGVQGTHVCQEADHVVIPPHVPPEVALELPEPEKAQRDIFAFFRGKMEVHPKNISGRFYSKKVRTELLQKYGRNRKFYLKRKRYGNYRSEMARSLFCLCPLGWAPWSPRLVESVLLGCIPVIIADDIRLPFPSVLQWLDISLQVAEKDVASLEMVLDHVVATNLTVIQKNLWDPVKRKALVFNRPMEEGDATWQVLRELEILLDRSQRRHVESWKR
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE).
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The hydrophobic-rich region (HR-A/B) corresponds to the oligomerization domain.
Sequence:
MAAAEAAAAVGKQQQKGGGGRGGGGGGPAPFLTKTNQMVEESATDEVISWGKEGRSFVVWKPVEFARDLLPLHFKHCNFSSFVRQLNTYGFRKVVPDRWEFANGNFRRGEQGLLSGIRRRKATTPQSSKSCGSGVNVAFPPPLPPLPPEPSATTSSGNDRSSSSASSPPRADITSENEQLRKDNQTLTMELARARRHCEELLGFLSRFLDVRQLDLRLLMQEDMRAAAGGVGGEQRVQEHAREEKCVKLFGVLLDDTHGAATRKRARCEEAAASERPIKMIRIGEPWVSVPSSGPARCGGDN
The following text describes a protein:
Function:
Alpha-1,2-mannosyltransferase that catalyzes the transfer of the third mannose, via an alpha-1,2 bond, from a dolichol-phosphate-mannose (Dol-P-Man) to an alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol intermediate to generate an alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H6) and participates in the nineth step of the glycosylphosphatidylinositol-anchor biosynthesis. May also add the third mannose to an alpha-D-Man-(1->6)-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H3) intermediate generating an alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H4).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MEQTGGSLFFKRRRSGSPKTVKLRKRKSVLYSNPPEGRAGNRSDLLGENIYLVLFTISLRILNCFLVQTSFVPDEYWQSLEVAHHMVFNYGYLTWEWAEGLRGYSYPLIFASMYKVLYVFAKDSVQLLIWVPRLAQALLSAVADVKLYSLVKQLENKEMAKWVFFCQLCSWFTWYCCTRTLTNTMETVLTIFALFYYPLEGSKFVNSFMYSSLVALAFIIRPTAVIPWIPLLFRHFWQEQKKLDLVLQHFLPVGLVTLGFSLIIDRIFFGQWTFVQLNFLKFNVLKNLGTFYGSHPWHWYICQGFPVILGPHLPFFIHGCFLTPRRYRILLVAIIWTVLVYSMLSHKEFRFIYPILPFCMVFCGHSLNHLKTWKKPALSFLFLSNVTLALYTGLIHQRGSLDVMTHIQGLCDNNSSASIFVMMPCHSTPHYSHVHCPLPIRFLQCPPDLNGNENYLDEADKFYFSPLSWLNQEFSSDILLPTHLVIFSVLEEEIKTFLITNGYKRIAVIFHTHLPEGRIGSHIYLYERK
The following text describes a protein:
Function:
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTILPRHKDVAKSRLNLRNPWHLLATGFGSGLSPVVPGTMGSLAAIPFWYLMTFLPWQLYSLVVMFGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITLMALPTTDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIGHHWPLGII
The following text describes a protein:
Function:
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation.
Subcellular Localization:
Membrane; Lipid-anchor.
Sequence:
MMDGPRSDVGRWGGNPLQPPTTPSPEPEPEPDGRSRRGGGGRSFWARCCGCCSCRHAADDDWGPEPSDSRGRGSSSGTRRPGSRGSDSRRPVSRGSGVNAAGDGTIREGMLVVNGVDLLSSRSDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESSDRITLELLIGNNPEVGKGTHVIIPVGKGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPRNEIYIIFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVSVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVEILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAIGSNMREDITYLYKHPEGSDAERKAVETAAAHGSKPNVYANRGSAEDVAMQVEAQDAVMGQDLMVSVMLTNHSSSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVELAPGASDRVTMPVAYKEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPAPGDGGFFSDAGGDSHLGETIPMASRGGA
The following text describes a protein:
Function:
Removes the phosphate from trehalose 6-phosphate to produce free trehalose. Trehalose accumulation in plant may improve abiotic stress tolerance.
Sequence:
MGLAKLDGNDFSIEYATWLVEHPCALEKFEEMMNIGKGKKIVILLDYDGTLSDIVPNPEEAFMTDKVQDFVKLKNVYYAGSHGLDIEVPLYSTNSNEKDFGTVENIIYVVLKEHPNFRVSTGIKVFEIGPNIVWNKGHALEYFLENLGFGNSDDVFPIYIGDDRTDEDAFKVLLKRGQGFPIVVTAAPKDTKALYSLREPKEVMEFLLGLVA
The following text describes a protein:
Function:
Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Subcellular Localization:
Nucleus.
Sequence:
MDLNWLCWDELALQEVPLGSVLEHPGLASGEADFYSSKASTLSDPRGLDPRTPGVGWKGLPANECGSDFPFPEFPWGTTDSSSLNLPCSGDWTDSTWFNPVSQPYCPTPFTYSESTGIADLTTSQASFTSWTTTPVPSGPTLWDCPNRPCWEGGSATAMEYPTPWEFSQLSGFSAPSSGCPFLSDSTPRSDRTIAVRGPRTGPRGPIQLWQFLLELLRDRAGQGCIRWTGNSREFQLCDPKEVARLWGERKKKPGMNYEKLSRGLRYYYRRDIVHKSGGRKYTYRFGGRVPDLP
The following text describes a protein:
Function:
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
Subcellular Localization:
Cell membrane. Late endosome.
Sequence:
MAQNCEKASKEFPLHWLIWNNRVAELQEMLCKGEHEHEKLDKHGRTPLHLAIALGHEDCVRVLLEANCSASALNAMKWTGPVIQHNYRFFTLALQEAVCLGKPNILKMVLKYRDRQQISSRVAAIPELLDMLQTYLLILVPLISRAFPNDVCKIWKKGAFLRVDTTLLSLDENIGKTGNRSIIFKAADNGAEIIEVDHEKRKACSETISLDEIGRRLGSEPSSELVFERLRMPVTSTIINIDNIEFSRQKSGIWGWRTDRTEAVNNYEAKVYNVSNVVVIARTRYEHLSEEDKERNKTEGRSFFHSLMGAIEQHSNEKDKTDAVPETIQQDKREDSSEIEQADLKSLSSQDYFYPTEETKKQDIGRPKEMSVKEQRLKASLWLCDDYYLSLQEQVLPIINLMAISNPHFQKLRDFISMQLPSGFPIKIEIPLYHILNARITFANLNGENEAVQGLSPLEAKLDTTDDVKQKNYLIDDSCFDIPSSYSKVLQRESNNFGADEEDMLLQYALQKSLSDRQLEESSETTAIGDEFVYRPYRYEMNENNDAELSWAIEESLRATRTNDANVNVQDPEMADPVMDTFVTANNFDDQLKMAMQLSTQVANEDSSRRIKEEEELRVALELSLLEK
The following text describes a protein:
Function:
May regulate extracellular matrix-dependent motility and morphogenesis of endothelial and non-endothelial cells; the function requires homotrimerization and implicates MAPK signaling; Probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix, basement membrane.
Sequence:
MAPDPSRRFCLLLLLLLLLLLSCCLVPTSADGNSLNPLNPLEWLWFAKTTDSLEARVSQPQISSPVQSPENPTTHVVPQDGLTEQQTTSANPKLSPEEDREAGQGGTPASPVVPIPLVAPAASPDTKEENVAGVGAKILNVAQGIRSFVQLWDEDSTTEHYPGIEASDSPVPTVLPTLAEPSSAPQGSETTLLLSSGIPSSPDSQTTEAGTLAVPTQPTPFQSSLQAPLGRPSVPPPSPGRAFLSSARIRAPPWGSQEPLRQPQHLEGKGLLPMATRSSRQHRHSDTHGHIPLLPLVTGPLVTGPLVTGPLVTASLSVHGLLSVPSSDPSAQLSQVAALPGFPGAWVSHVAPSSGSELSNDSALVGNDSLTSPSRCLPLPPTLAICSHLGIGHFWLPNHLRHADSAEVEATARAWGHLLHTNCHPFLSWFFCLLLAPSCGPGPPPALPPCRQFCEALEDACWNYLAGDRLPVVCASLPSQEDGYCVFIGPAAENVAEDVGLLQLLGDPLPQKISQVEDPHVGLAYVFGPYSKSSQMAQYHFPKLFFRDFSLLFEVRPTTEAAGVLFAITDAAQVVVSLGVKLSEVRDGQQNISLLYTEPGASQTQTGASFRLPAFVGQWTHFALSVDGSSVALYVDCEEFQRVPFARSPHGLELERGAGLFVGQAGAADPDKFQGMISELRVRKTPRVSPVHCLDEEDDDDDRASGDFGSGLEESSNLHRQETYLRPGLPQPPPVTSPPLAGGSATEDSRTEEKEEEATVDSKGADTLPVTDSSGVWDGDVQNPGGGLIKGGLKGQKGEPGAQGPPGPAGPQGPAGPAVQSPSSQPVPGAQGPPGPQGPPGKDGIPGRDGEPGDPGEDGRPGDTGPQGFPGTPGDVGPKGEKGDPGIGPRGPPGPPGPPGPSFRQDKLTFIDMEGSGGFSGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSYAPGPAGLPGVPGKEGPPGFPGPPGPPGKEGPPGVAGQKGSVGDAGSPGPKGSKGDLGPIGMPGKSGLPGLPGPVGPPGPPGPPGPPGPGFAAGFDDMEGSGTPLWSTARSSDGLQGLPGLPGIKGDPGVTGPPGAKGEVGADGVQGIPGLPGREGVAGPPGPKGEKGTQGEKGNPGKDGVGRPGLPGPPGPPGPVIYVSNEDRAVVSTPGPEGKPGYAGFPGPAGPKGDLGSKGEQGLPGPKGEKGEPGSIFSPDGTALGQAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGTNGLKGEKGEPGEASLGFSMRGLPGPPGPPGPPGPPGVPVYDSNAFVESGRPGLPGQQGVQGPPGPKGDKGEVGPPGPPGQFPIDLFHLEAEMKGDKGDRGDAGRKGERGEPGAPGGGFFSSSVPGPPGPPGYPGIPGPKGESIRGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTVSVPGPPGPPGPPGPPGAMGASAGQVRIWATYQTMLDKIREVPEGWLIFVAEREELYVRVRNGFRKVLLEARTALPHGTDNEVAALQPPLVQLHEGSSYTRREHSYPTARPWRADDILANPPRLPDRQPYPGVPHHHHHHHHHHSSHEHRPPAHPSPSPAHTHQDFHPVLHLVALNTPLSGGMRGIRGADFQCFQQARAVGLSGTFRAFLSSRLQDLYSIVRRADRSSVPIVNLKDEVLSPSWDTLFSGSQGQLHSGARIFSFDGRDVLRHPAWPQKSVWHGSDPSGRRLMESYCETWRTEATGVTGQASSLLSGRLLEQKAESCHNSYIVLCIENSFMTSFSK
The following text describes a protein:
Function:
Directs RNA polymerase II nuclear import.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPAVVRIKRRIDEEPQTAFVLNGKRRRLHNDENALEDAGAVAGAVAGAVASDKDELTTVLKFAGTLEKQDDCATRKFAAARLNKAAARDLVQQQRSNDAAIASALRRDRQRQEAQENSREQRFRVVNCLRSTLENSAAEAECPESQSHESSSHITIVDIESQQQQHMGTASAAAEEQQQQEIAPSQDQQQPADSDVGYVYDLYVPENEMQAAYVDMMDDNYLSVIPVGEIVLEDCYNDQDEDYDSEDSNQENYFTNDYPDDDEAGAMGSDDELCRQMNKFMLDDDEDEFASTSDDDDYATFRDPYVHTIDTEEDSFVDDVDFYNVDRERGSAYERYKRRILKELEGQEEEDEDDDDDDDSFASADGE
The following text describes a protein:
Function:
Plays a role in the export of secreted proteins in the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSLQWAAVATFFYAEILAAVLLCSPFISPQKWLKIFRSRLVRQVVNRGKPYFSVLLLILVLLFMDALWEMRKFDSSEKKGLRNNTVALEQYHMKLYRAQWNLHLTSFSLLMSLLLRRLVTLQSQQALLQASREALRRQALGALEAAQRFLDENERLRAEDEALALRKRCEGVPQEHDHLAEQHHEAGEGLPEDQKNK
The following text describes a protein:
Function:
Plays an important role in the elongation step of protein synthesis.
Sequence:
MGVFTFVCRDSGAEWSAKQHKGELEASAATPYDLQRQLVSAACAEDKSGGVQSSFTMVSPKSAIFQVVIGGASAGPIGGGAAAGGAAASGGAAAEAPKGEEKKEEEKEESEDDLGFSLFD
The following text describes a protein:
Function:
Required for the biogenesis and accumulation of native cytochrome b6 in the thylakoid membrane. Controls the conversion of apocytochrome b6 to holocytochrome b6. Required for covalent binding of the c-type heme to cytochrome b6.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Sequence:
MSIQICNFPFHPKFALQPRAQRSTRIFARTENDSPQSKTSDQQLNLSVLRFTFGIPGFDESYLPRWIGYGFGSLLLLNHFSASAPISESQMRSEALGLSLAAFSIALPYIGKFLKGSVVEQRSLPEEGEQVFVISSNIGDSLKEDLAWATYVLLRNTSTIAVLISVQGELCVRGYWNCPDQMSKAQLHDWFKKKVDEIGLADVKETLYFPQYAGSALSLDILPDGTRSLFVQPLVQNTNEPQKVNGFLLVASTAGYAYSDKDRAWIGAMAEKFRG
The following text describes a protein:
Function:
TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.
Subcellular Localization:
Nucleus.
Sequence:
MPSLAVPHLTPISNEHLVSSKEVVFFWKNRIEMFEKKSDKVKQAEHKARDDGVELESQFIMRVPKELADTVHEAINAGTIKDRLTIQLDPDLRYGEVRIDDQILYTKLVDLPTVVESYKTIDNKSFYKSADICQILICKEEREDETEKESPNKNKKKDPNKVDKKYLFPHGITPPCKNVRKRRFRKTLKKKNVEAPEIEKEVKHLLRIDNEAVRVDYEIINEEDKPMDELEQSDIKPYNDADDDLQDESTMHASEKTIMEMSSQRHLQVESDDDEASNFPSHRAPNMGVAVHDIFGEEVSSTDDEDEPDRGNNTMQRRVMEESSRLSADDSRMSDFFGASGSNTGAGVVKMEQNVFSKSMFGHEASSPKLSAAGSSSNLAAPSGFYDSQMLAKREEFENMEFIDEPQPQYTQQQVQQKINQLTRQIRELKAQQVQKSTEIASIQNATLKQRMQETLDNLYTQVIERELELKDFENMLES
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane. Mitochondrion membrane.
Sequence:
MSNLVKIAKVVLPMAVPGTLGLMSTTVFAASNAKENSAILMTDELSLYDTPEPRLRYEEPDVGPVEQGVASLRKTVEPYCSWCQERTQFAVDKIQSYYKTVEPGVDTTQNIVQDIFTFLKDPPSEFYPSVGVIGFSGILGLFFAKGSTVKRLIFPTGLMALCASVFYPQHAASAARTTKDYMYSWGSEGRAVLEELLRGKSSSKDKADKTQKSDSQKSS
The following text describes a protein:
Function:
May be a transmembrane transporter of the mating factor, namely P-factor or M-factor. Confers resistance to leptomycin B and to several other antifungal drugs.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSLHSKKSTSTVKDNEHSLDLSIKSIPSNEKNFSTEKSENEASESHVVDVVKDPFEQYTPEEQEILYKQINDTPAKLSGYPRILSYADKWDIMLQLAGTITGIGAGLGMPLMSLVSGQLAQAFTDLASGKGASSFQHTVDHFCLYFIYIAIGVFGCSYIYTVTFIIAGERIARRIRQDYLHAILSQNIGYFDRLGAGEITTRITTDTNFIQDGLGEKVGLVFFAIATFVSGFVIAFIRHWKFTLILSSMFPAICGGIGLGVPFITKNTKGQIAVVAESSTFVEEVFSNIRNAFAFGTQDILAKLYNKYLITAQRFGINKAIAMGLMVGWMFFVAYGVYGLAFWEGGRLLHAGDLDVSKLIGCFFAVLIASYSLANISPKMQSFVSCASAAKKIFDTIDRVSPINAFTPTGDVVKDIKGEIELKNIRFVYPTRPEVLVLDNFSLVCPSGKITALVGASGSGKSTIIGLVERFYDPIGGQVFLDGKDLRTLNVASLRNQISLVQQEPVLFATTVFENITYGLPDTIKGTLSKEELERRVYDAAKLANAYDFIMTLPEQFSTNVGQRGFLMSGGQKQRIAIARAVISDPKILLLDEATSALDSKSEVLVQKALDNASRSRTTIVIAHRLSTIRNADNIVVVNAGKIVEQGSHNELLDLNGAYARLVEAQKLSGGEKDQEMVEEELEDAPREIPITSFGDDDEDNDMASLEAPMMSHNTDTDTLNNKLNEKDNVVFEDKTLQHVASEIVPNLPPADVGELNEEPKKSKKSKKNNHEINSLTALWFIHSFVRTMIEIICLLIGILASMICGAAYPVQAAVFARFLNIFTDLSSTDFLHKVNVFAVYWLILAIVQFFAYAISNFAMTYAMEAVLQRIRYHLFRTLLRQDVEFFDRSENTVGAITTSLSTKIQSLEGLSGPTLGTFFQILTNIISVTILSLATGWKLGLVTLSTSPVIITAGYYRVRALDQVQEKLSAAYKESAAFACESTSAIRTVASLNREENVFAEYCDSLIKPGRESAIASLKSGLFFSAAQGVTFLINALTFWYGSTLMRKGEYNIVQFYTCFIAIVFGIQQAGQFFGYSADVTKAKAAAGEIKYLSESKPKIDTWSTEGKKVESLQSAAIEFRQVEFSYPTRRHIKVLRGLNLTVKPGQFVAFVGSSGCGKSTTIGLIERFYDCDNGAVLVDGVNVRDYNINDYRKQIALVSQEPTLYQGTVRENIVLGASKDVSEEEMIEACKKANIHEFILGLPNGYNTLCGQKGSSLSGGQKQRIAIARALIRNPKILLLDEATSALDSHSEKVVQEALNAASQGRTTVAIAHRLSSIQDADCIFVFDGGVIAEAGTHAELVKQRGRYYELVVEQGLNKA
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. Also required for formation of 2'-O-methyluridine at position 1369 (Um1369) mediated by MRM2.
Subcellular Localization:
Mitochondrion.
Sequence:
MAAPAKGMWCSLGSLLRVVQTRDLNARRWVRALRRSPVRVLSPSGQVEERKRAPDQQPRKAVPKASSQGQRQKQPLETSPSQTPHTWEEAGLRYDKAFPGDRRLSSVMTIVKSRPFREKQGKILLEGRRLIADALKAGAVPKAFFFSRLEYVKELPVDKLKDVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPDPVKMTYPETPLHHTLPLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPPDTRVYVADNCGHYAQVQMSDKTGDRDWACDRRFLKFHKYEEDLDTKTRKDWLPKLEVQSYDLDWTGAPAAVVIGGETHGVSLESLQLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRIKVEDLSRDRSYH
The following text describes a protein:
Function:
Controls the rotational direction of flagella during chemotaxis.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MKKKLMIILLIILIVIGALGAAAYFVLGGKSEKSEAKKSIDEIVASSVDVEEITTNLKSDNIIRLAIKLETDSDKSKEELEKRDFQVKDAVISLLADTNADQIEGDKGKETFKKELKDKINSYLQEGKVEKVYITSFNLQ
The following text describes a protein:
Function:
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Sequence:
GGCGGGGGRSPRGDPGARQPPPPHPAPRRRCPHPQGFRLAAWREGGVRAAPGRRLGWGLKEVLQVALGATPQGRGRRQPPPRRGGGGGGGRAPVGRGGPRTTPGHRRVTAGSAWAEPRSEREEARGRWFPGAGAATRAYRLPGPRPRDPGPAGVGSEPRRHSGPSRAEPSRVLRRVPPRAPAARTCRPHLPRSPAAQRASGRPQHDRPGGLRHGYRHPDPLRHGGGQEGPRHRRDDPAAQLALHRRQSHFHGRAQGGHCAPGKYVVCFDPLDGSSNIDCLASIGTIFGIYKKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVNGVNCFMLDPAIGEFILVDRDVKIKKKGNIYSLNEGYAREFEPAVTEYIQRKKFPPDNTAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPKGKLRLLYECNPMAYIMEKAGGLATTGKEAILDIVPTDIHQRAPVILGSPEDVKEFLDIYKKHAAK
The following text describes a protein:
Function:
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
Subcellular Localization:
Endomembrane system; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein.
Sequence:
MLKPLLLSLFMVLHTQAEQLAKNDCTLLKQNQQSQELLKRLDPLKGKIFTYKFKDEINGGDEYDYTLSICSGVTANQFNAPGVGVLQYNKLKQEYKRVGLINSTVVKGGTDWIMLTYKHGDRYHSHCTSPGSELSRRQAHIMIVCDPNELEGQFKVLYEHNDEDTESSCFYMMEISSRAACSHVNGLSTGSILLIIFVSVTSAYLLIGVVYKRCVYGSKGFEQIPNIVFWRMCGNLQADGCDLLCR
The following text describes a protein:
Function:
Plays a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein.
Sequence:
MWRTCLRLRDGGRRLLNRPRGGLIASEGRGPSPPTPARAYAPPAERKRFYQNVSITQGEGGFEINLDHRKLKTPQAKLFTVPSEALAVAVATEWDSQQDTIKPYTMHLTTLCNTSLDNPTQRDKGQLIRAALKFLDTDTVCYRVEEPETLVELQRNEWDPVIAWAERRYGVEISSSTSILGPSIPARTREALVSHLASYNMWALQGIEFVVTQLKSMVLTLGLIDLYLTVERAVLLSRLEEEYQMQKWGSIEWAHDYELRELRARTAAGALFVHLCSESTTVKHKLLQG