lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MARKAKKKGTSGAATNYINRRKAIRKLQLSLKDFRRLCILKGIYPVEPKYRRHVNHGSSVHNTYYLLKDIQFLAHEPIIQKFRDFKVFIRKLRKALGKNERDTAEHIRNNEPVYRLDHIVKERYPTFVDALRDIDDALSMCYLFSTFPNGKVVKPTLVGLCRRVIVEFMHYVIETRALRKVFISIKGYYYQAEIMGQTITWIVPHNFSFRQPVDVDFKIMVTFADFYVTLMGCINYKLYHTLNLHYPPKLQHEVVEDNSNADDEDDTSEDDLTITHQIADRPLLKKRYINRYYVQPQWVYDCINFRRLLPVEDYFLGEELPPHLSPFVEEKEGDYVPPDKLDMLQGRRRARDEESEDEGIEEEGLEEEEDSGEESGEENDDDEGDDDDEEDDEGEELEKEHLSRKVQAAKRKATADRKAAPNKEEEGGSKKAKMAVQAGVVVKEDPAKAAQKQKSEEKRLAVMMIPKKHKKLYEKIVFGQKRRAREVGAPLPFPPHTHI
The following text describes a protein:
Function:
Involved in the uptake of GABA into the synaptic vesicles.
Subcellular Localization:
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Sequence:
MASNRFQNLQNWTNKHVFSNSLDYWNQELNEVPSYQNQPQTGESGSNPPPHDRLEPIQESVVSEQPQKDDINKQEEAKDDGHGEASEPISALQAAWNVTNAIQGMFIVGLPIAVKVGGWWSIGAMVGVAYVCYWTGVLLIECLYENGVKKRKTYREIADFYKPGFGKWVLAAQLTELLSTCIIYLVLAADLLQSCFPSVDKAGWMMITSASLLTCSFLDDLQIVSRLSFFNAISHLIVNLIMVLYCLSFVSQWSFSTITFSLNINTLPTIVGMVVFGYTSHIFLPNLEGNMKNPAQFNVMLKWSHIAAAVFKVVFGMLGFLTFGELTQEEISNSLPNQSFKILVNLILVVKALLSYPLPFYAAVQLLKNNLFLGYPQTPFTSCYSPDKSLREWAVTLRIILVLFTLFVALSVPYLVELMGLVGNITGTMLSFIWPALFHLYIKEKTLNNFEKRFDQGIIIMGCSVCISGVYFSSMELLRAINSADS
The following text describes a protein:
Function:
Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MGAMEGECYFYDFYDFGGGLGSMIRHAPELEEITILPETPASPLNTTTTTNTNFNFEMSDDASPRGVLTPDMIRIEYPQLPLAIEDKWKPLFDKYDLDRDGVISVQRFLRVLQHRDMAGDIDAHHLSLVQELLQQDDMGNISFQQFVNIMSNKRRNSFRSAVLSRDRCLNNGDVSSYQLVQPDDLPKTCFQKSVHRVAKEVLTEESDRKIYSDYYSCFPPPLLMIILSLVQLGFFVYYAATWDSFSAAGWLSGPVPVDSPFIYNPAKRLQIFRFFTYIVLHAGVEHLVFNLAVQLLLGVPLEMIHGTFRVGAVYLAGALAGSMSTSVIDRTVYLVGGSGGVYALLAGHLANVLTNYTEMQETFGIAKIGLILIITSADVGFSIWRRYNDHPKDTRVSFLAHLFGLLAGLTIGLLILRNFEQKLHERVMWWVSLVVYAACIIFTIFWNIFYY
The following text describes a protein:
Function:
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MGQIKDILTTLLPLVVLFLIFYFLIVRPQRQQQKKHKEMIESLTKGDKIVTQGGLIVEVLKAEANFFSVKLNDDTTAKLSKNYVAFKLDELDQFGLAEPIVIQQGREEISAKLSGAKTLKQRQITTE
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Domain:
The PTS EIIB type-2 domain is phosphorylated by phospho-EIIA on a cysteinyl residue. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the PTS EIIC type-2 domain; The EIIC type-2 domain forms the PTS system translocation channel and contains the specific substrate-binding site.
Sequence:
MKMKIAIVTACPSGVANSIIAAGLLQQASKTLGWEAYIECHSTVIAGHTLSEEEINKADLVILAANGKIDMQRFVGKKVYQSPITACTSDPVGYLKQAAEQATELSSEQATRCDSPATASVSAKKIVAITACPTGVAHTFMAAEALEAEATRQGHQIKVETRGSVGAKNQLTEQEIAAADLVIIAADIDVPLDRFNGKKLYKTSTGLTLKKTAQELSNAFAQAKTFSSSANSATNEKAEEKKGVYKHLMTGVSHMLPVVVAGGLIIALSFVFGIEAFKEEGTLAAALMQIGGGSAFALMIPVLAGYIAFSIADRPGLAPGLIGGMLASSTGAGFLGGIVAGFLAGYSAKFIADKVQLPQSMAALKPILIIPFIASLFTGLVMIYVVGGPMSSIMSGMTSFLNNMGSTNAILLGIVLGAMMCFDLGGPVNKAAYTFGVGLLASQTYAPMAAIMAAGMVPALGMGLATFIAKDKFEAGEREAGKASFVLGLCFISEGAIPFAAKDPMRVIPACMVGGAVTGALSMLFGAKLMAPHGGLFVLLIPNAISPVLLYLVAIAVGTAITGFGYAMLKKSAQAKAVAA
The following text describes a protein:
Function:
May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
Sequence:
MLKSTFTPIFWVLTPKPKPPKLPSHAITNTFFTSSMPHVRHNAPVNPITPPPASSAYIHLPFCRKRCHYCDFPIVALGSTSALIDDDPRVSNYIHWLCREINATNVDQPDDANTITPLQTVYFGGGTPSLVPPRMVSSVLDTLRTKFGLREDVEISMEMDPGTFDAEKMRGMVVLGVNRAFREELLRACGRAHGLKEVHEAIDVVKLCEVENWSIDLIASLPHQTSDMWEESLRLAIEAQPTHVSVYDLQIEQGTKFGRLYSLGEFPMPSETQSAEFYKMASRMLSDANYNHYEISSYCKSGYECKHNFIYWKNKPFYGFGLCSASFVGGLRFSRPRKVNDYINFVQNLENGFVNSSVEGHIHGKDTVMDVVMLSLRTAQGIDLMSLQESFGSSIVLSLLEAYKTYFESGHVVCLDEYRRTVRIDDLNSFLNNTNAEGRVAYIRLSDPEGFLLSNELIAIAFGVIDSWKDMPPYQEAEAT
The following text describes a protein:
Function:
Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation.
Sequence:
MDVPGSSSGSSSKRGRKLRQCSGDSTKSDPTEASSESDFDPNGSFQKGESSRRRCERQKQLGLKFAALAYESNYEDGEHKSAFLPYRPRTVLTNLQRGNVQTEAVVVNPVQLSFHQRAGKGEITKADIDAGTNDINGLDERGLTPLMWSSAYGQVPTAALLLKAGAIHSIKGPDGETAIHLAAAGGHTDIIRLLIGAGASVNEIDDNSNTPMMFAAFGNHPHALNELLNNGGDITMTNLNDDSALSIAVKRSSKEAQSVIEGYLFMLLQPQN
The following text describes a protein:
Function:
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MEQQSPVGALLFQIIFLVAIFLMFYFLIIRPQKKERERHRKFLESLKKGDKVITSSGIWGTVVEIGDRTITLKVDANTKITFSKEAIVAYQPGYEKKEEKKD
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of 2-phosphoglycolate.
Sequence:
MTIKAISVDIDGTITYPDRRLHEKALEAIRLAESLGVPVMLVTGNTVQFGEAAAILIGTSGPVVGEDGGALSIKEGKLRKRVYLTNMDEEWILWGELKKRYPEALLSFSMPERKAGLVVLRTVPVKAVRELIKELGLNLIAVDSGFAIHIKKPWINKGTGIEKACEYLGISPKEVAHIGDGENDLDAFGVVGYRVAVAQAPESLKEKADYVTTKPYGEGGAEAIEHILRKFGYLPEEKT
The following text describes a protein:
Function:
Binds to the 23S rRNA and protein L31.
Sequence:
MQVILLEPSRLGKTGEVVSVKDGYARNWLIPQGLAVSATRTNMKTLEAQLRSIEKRQAQEKAVAEDLASRLNGVAVELSVRAGEGKIYGAVTHQDVANSLDQLGFDVDRRKIDMPKTVKEVGEYDIAYRAHPEVTIPMKLVVHAAK
The following text describes a protein:
Function:
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
Miscellaneous:
MISCELLANEOUS: Present with 5150 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMMLRLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDADIYEEKRRREESAQHTETPMSSSSVTAGTPTPHLDTPQLNNGAPLINTAKLDDSLSKEKLLTNLKLQQSLLKGNKVLMKVFQETVINAGLPPSEFWSTRIPLLRAFALSTSQKVGPYNVLSTIKPVASSENKVNVNLSREKILNIFENYPIVKKAYTDNVPKNFKEPEFWARFFSSKLFRKLRGEKIMQNDRGDVIIDRYLTLDQEFDRKDDDMLLHPVKKIIDLDGNIQDDPVVRGNRPDFTMQPGVDINGNSDGTVDILKGMNRLSEKMIMALKNEYSRTNLQNKSNITNDEEDEDNDERNELKIDDLNESYKTNYAIIHLKRNAHEKTTDNDAKSSADSIKNADLKVSNQQMLQQLSLVMDNLINKLDLNQVVPNNEVSNKINKRVITAIKINAKQAKHNNVNSALGSFVDNTSQANELEVKSTLPIDLLESCRMLHTTCCEFLKHFYIHFQSGEQKQASTVKKLYNHLKDCIEKLNELFQDVLNGDGESMSNTCTAYLKPVLNSITLATHKYDEYFNEYNNNSN
The following text describes a protein:
Function:
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.
Subcellular Localization:
Cell projection, cilium, flagellum membrane; Single-pass membrane protein. Note=Predominantly located in the principal piece of the sperm tail.
Sequence:
MESPLIYVSVLLLNIFEFSSGIVYNKDDTEKRFACSNKGFPQENEIIKLYLFLENLKIQCFFQTENEIASKAMLSVFTSGGLAPSLGIMNSTYNGIFHFNLTLFSDRILWLVDIPRENITQSTDIAAVEEWLVRITLHHGLNIYATEGTLLDVIREPILQWTPGDVIPESEISKLYPHVVDLKVTKCPCANDVALLGFIVDTIVDGVYIGITFGGFWHDYDTTWFNMTQTIYSQLQEEYEDLSLVDMVLTNHFLVILTSLGLFVSEDLRYPSRHSLSFSRADFCGFERVDYVKGKLWYNERCFANREHFEVDYVTVTFERNRTLSESSSCFYSQEPFLEWVPCLPHIFKGIKIFPTVLTFLVDQERGTGVYLFYNKVRKTAIASVSTLRNNEPNSQSKFPIFRFPSSFSSPVGMVFHPRSHFLYAYGNQIWLSVDGGNTFQLIANFHDDIIKKTFHSFYTSAITFVSQRGKVYSTKAGMGRYSAVGSVTERIFTLYYDHLGFLHKLTLGRFEASGPPTAFGNSRNLFGQPPDMGFETALAPQHTSLDEIIFFAYVPENEPQETIYSKKFGNIHYGKVIHSGKTGRAYIRKVLQHTTPKGFLSSVIAEMKEPFGLEEVNESSCLSSSLLINKAGNVYKLTLDSQVVQALFEDTDIEKTVVLPGYSSFLITSILDNKNALAIATMPESAPNNMTFLKSTWFLYNFGQRNGRTWKIYSKPCNYWFQHDDSPSLNIVKYIDLGNSYVLKAKVIRNAKGFRMLEIPLLTVFVGNPNLLEVTAEVTFDDTDSYVITISAASKVLHQGSTSLAFIMWSASTECFVTTMVPTLKSSCSYLRSMHHIPSKFIPFEDWISGVHKDSQGFNLIKTLPINYRPPSNMGIAIPLTDNFYHADPSKPIPRNMFHMSKKTGKFKQCANVSTREECNCTKDQKFSHAVAFSDCREKVPRFKFPITQYPVSLEIINEDGRVPLQSPYLVTVTEVNMRHNWKLKHTVPENIKRMKQLVEPILGAAVYNPSGLNLSIKGSELFHFRVTVISGVTFCNLIEEFQIYVDEAPLPFPGHTLIAVATAVVLGGLIFIAFMFQLQGIHPWRTFQRWIRRNQEKFSSISLSELIHRSKSEE
The following text describes a protein:
Function:
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin.
Sequence:
MLVFTTSPDHVDELNEFVQQLNPVAFTRVLRGLGKVLASYNDKAVEEDTLKKSSTGSLPSGQQVHCQYVLDDPNHVEGISVDQSLQVPKFEKNWLISPPGSPPVGWEPIVEESPNSQHLAHDIQLKLDELGNALLNDHSAGPQIVISEHNNTKETSPSRQFEH
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MECSNKERQNRLIGCCKSRMDLSYRCFVVCILCISIFLSGPTKTDASATWMWLGAASLGAASVGRDTIPDGSLGHQTATQAPPINSILVDPETLCQRFPGLTVEQRRVCSSTPEIINMISEGAKVGIIECQRQFSTERWNCSVIGDVNNPFGEVMNTGNKETAFIYAITSAGVVYAVTRSCSLGNLTECGCATPRGQPSDDVVDDDEEWKWGGCTDDVDYGIKLARKFVDSGDKYSSSSSLSSPSPPPSALSRPLTIKPGVQEMNLHNNEAGRQLIKSGMKTLCRCHGVSASCSLKTCWKAMPSFKEIGDLAKSRYSEGVEVVVRTKKQIRLRRKDRRVRREVIASDELVYMQRSPNYCRTNREIGIVGTTGRECNRTSTGSDSCDLLCCGRGYNTQVIRRVERCDCKFIWCCKVKCRVCETVTDIYTCK
The following text describes a protein:
Function:
Plays an important role in the control of DNA replication and the maintenance of replication fork stability.
Subcellular Localization:
Nucleus.
Sequence:
MTSTVRATGCYKCGKPGHWSRDCPSQPASENPTPGSASVPSSSGVFAAAKGGTQASTQGFKRKEPWRGGEKSGSFGPREKPAKARVPPRRMPKLTPDLLLGDDGLGYVLEKIPRQVNIRGRGHEVEDLKSLLEAYVRWHQNLLPYYSFSQFVEKVEKVGSTKRVRLCVRELRSKVEKEKNSLGADANSNADDDEAPDTKWEENDGDAAEDHGDPPMDVLEEHLRESAHASVSNLVEAAPASAPRPTIVIGPEPSTVAQQELKEEQRARMEANKQKALERARARKLELEKANSTPLT
The following text describes a protein:
Function:
Required for maturation of 30S ribosomal subunits.
Subcellular Localization:
Cytoplasm.
Sequence:
MTVSSEEISGILDGVLSLPVKLYSLKVNQRPNHSLIEVVLDNLEHPYGSVSLLECEQVSRKLKEELERISPDLDYTLKVSSAGAERKLNLPGDLDRFRGIPIRLVFRSEESEKEQEGIFRVVNRDGDQIVLEKFQKGKKSVVKKQTTLNLKDILKGNLYVNI
The following text describes a protein:
Function:
Catalyzes the biosynthesis of agmatine from arginine.
Sequence:
MACTTFQVTSTNLGSALASRKHCCLRPSSQVSSAIAGAFPEVRRLHDKTRAGSSWAQKYAVSLGERKGLERQHISKQRWRIRVHSGVASRSSESNGVATPERLPSAAILDQDGDLDEDWEAAWTPQDAADLYRVEGWGSPYFSINARGNVAIRPKGSEDGSDELDLLELIQAVRKRNVELPMILRFPDIVQHRMAQLQGCFDTAIGKYGYQGHFQGVFPVKCNHDRYLIEDIVEYGRNFRFGLEAGSKPELLIAIANLRENDDALLVCNGYKDEIYMESVLLARQLGTNAVIVLEQVDELPLLLHVSRKLDVRPVIGVRAKLSTKHDGHWGGTSGDKGKFGLTIPEIVKVVYTLREEGMLDCLQLLHYHVGSQVADIAIIKEAMREGSHLYCELATMGAAMGYIDVGGGLGIDYDGTKGNRSGASTNYSMQNYANDVVAALLDACVVKGVRQPVIASESGRALASHSAVLVFDVLNDSENAESDALRNLAVLEEHHAAGLGSIQQGWPPKQDGLATNGLQPARRDPGQYLLSTFYQVFATIDQTNFQEAFNDSKQFKQEAANLFKLGCLSLEQRAQAESLHTAICHRVLAYARNEPQMPAELSALSEAMASVYHVNLSVFRSAVDTWAIDQLFPIMPLQRLSEEPTTMATLADLTCDSDGKITRFIGPDSTPSSVLPVHELRQGEAYYLGMFLGGVYQEVMGSLHNLFGGLNVVHIRAKPKPGRAAGGYAIEHVVKGQTMEEVLRTVQYEGEDMMESLRNEAEEAVDEGRLTLEDASALLMNFNRSLKSYTYLKSRSQ
The following text describes a protein:
Function:
Integral membrane transporter that imports quinic acid to be catabolized as a carbon source.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGGVADSSAAMDAAAQMRKAALKGSSGMAGLVQNRKVFGIAMFACLGGLLYGYNQGVFSGVLTMYSFEKHMGDAVTNQTKKGWLTAILELGAWFGALYSGLLCERISRKYTILANVAIFCIGVVIQTTAATKGGNSSHILGGRFITGMGVGSLSMSVPMYNAEIAPPEVRGSLVALQQLAITFGIMHRINYGTNHIGGTGPTQKDAAWLLPLALQLVPAVILGAGMIFMPFSPRWLIHHDREDEAKKVLTSLRGLPADDPLLQLEFLEIKAQSLFEKRTEKEKFPHLERTNTWSYIKLEAAGFASLFTSWPMFRRVMVATVTMTFQQWTGINAVLYYAPSIFNQLGMSSNTTSLLATGVVGIVMFIATIPAVIWIDRLGRKPVLVVGAIGMAACHFVIAAIFGQNENQWDTHKAAGWAAVSMVWLFVIHFGYSWGPCAWIIIAEIWPLSVRAKGTALGASANWMNNFIVGQVTPDMLQNIRYGTYIFFGIITFLGAGFIAFMVPETKQLSLEEMDVIFGSEGTAISDYERQAEISREIGLDEALARLTNTAPVEVHDVEAKQT
The following text describes a protein:
Function:
Involved in recognition of centromeres and centromeric localization of the centromere-specific histone CENH3. Required for normal progression of mitosis and meiosis. May play a role in the determination of the epigenetic status of centromeres. Binds DNA and RNA in vitro.
Subcellular Localization:
Nucleus, nucleoplasm. Nucleus, nuclear body. Nucleus, nucleolus. Chromosome, centromere. Note=Localizes at centromeres during all stages of the mitotic cell cycle, except from metaphase to mid-anaphase. Colocalizes with CENH3 at centromeres in interphase nuclei.
Sequence:
MTEPNLDEDGSKSSFQKTVVLRDWWLIKCPKEFEGKQFGVAGFEESVETRAMRVFTSSPITKALDVFTLLASDGIYITLRGFLNKERVLKNGFNPEISREFIFGFPPCWERVCNSCFEGDSFGTDVNTVPSTIEKACPPILSPCKYSNRNLKDNPAESREKSNVTETDIAEINDKGGSGARDIKTARRRSLHLQIKRILESSKVRKTANDGDHGSEFLNTAKRGDVERDGCEVINNEDSEWKLDESEVQNLCNDGDNGSEGFIKAKSSDVEKDKSEAIDNDVISPAVGSGIKHTGADNVDKVTSASATGESLTSEQQNGLLVTTASPHSLLKDLAKSSKPEKKGISKKSGKILRSDDNVVDPMNYSGTKVKSAENKRKIDASKLQSPTSNVAEHSKEGLNNAKSNDVEKDVCVAINNEVISPVKGFGKRLSGTDVERLTSKNATKESLTSVQRKGRVKVSKAFQDPLSKGKSKKSEKTLQSNSNVVEPMNHFRSEAEEAEENLSWEKIKRKIDFDVEVTPEKKVKQQKTNAASTDSLGQKRSRSGRVLVSSLEFWRNQIPVYDMDRNLIQVKDGSETNSAPSKGKGSDSRKRRNLKIK
The following text describes a protein:
Function:
Involved in retrograde transport from early and late endosomes to late Golgi by linking the vesicle through the t-SNARE TGL1 to the Golgi, leading to the membrane fusion between late Golgi and endosomal vesicles.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
Sequence:
MQRASTQDVYDGSGDDLNKLDSLKSVLNDVLSSLERFQVDLDVATSDIYKVSERSNKIQVNLNNLKAVESALGAEIDGAILPPDLIKTISTGDMDHPSWNSALEKLTSFLEGGEDDSSLGNMFNSLQINKDQKKLVDKLRDKAIERIRNYIVVTIKMFRQAFVDVFPIRKHRLIANKNYYLFLFKFNRKLALELQRAYINTMNWFYLYHFEQYSRFLDKVHVLKGETIRVEEDRKGLFNLSKGAQQSYGNQMLSVNLRPQDFDMNSVLTASTMHHIESSPQYIERVYCSWELVLTEHVSSEYAFLLEYFNLSKDQQATVFAAIFEKTLHFSRKYITGLISSSIDCIGILKSIRFTQKLALQAQTNIVPVIEPHYNSMILFLWPRFQAVMDMHCESLRKTNLSVKPEEITSRPHPLSQRVAELLYSLSMLSVNVVEAEPVARSASRLAQDYVSMLQNLCKTVNDKRRQSRFLSNNYTLISTVLSGVSGNLAIEQKTYFEKLNENLTNFQ
The following text describes a protein:
Function:
Regulatory subunit of protein phosphatase 6 (PP6) (Probable). In complex with pph-6, promotes actomyosin contractility during cytokinesis by regulating the organization of cortical non-muscle myosin II nmy-2 and thus contributing to correct spindle positioning. Also required for the proper generation of pulling forces on spindle poles during anaphase by regulating the cortical localization of gpr-1, gpr-2 and lin-5. Negatively regulates kinase air-1 localization at the cell cortex.
Subcellular Localization:
Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=In embryos, localizes mainly to the cytoplasm and to a lesser extent with microtubule asters.
Sequence:
MFWAKEEEENSLMRLLKTDNFTLEDVLLNEFVVQESRYGKAELVQYITSRENMKALLELSLNPKINTDLPMKQQYRLSFIASEILTIRGTDVFQKQIVTTEETRKCLVDFLNDKTPLNHLVAGFFAKIMECLLSRHFDLFQTFSLLQETKFFDKCLRNINLGAIECLLENLVRIPTTSEGTRIVKEWMISENLFEKIVDRMRESETDDEKECLAEVYCEILRELRDKLYIMESKVDELHAKSMDETLIAKIADNLIVEEGCPAEELVKKSALISASAKILEAFIKTNFVSNAPAQQLEEIERNLIEERHYSYGLMRPCMDNDPYEHSYQPDPERIVEGILANRLPNILQTVLRDIEANGSVWQPLLRLIIELCNTNCMSTHEKIAVAFRSLPFINLIKAAKMLPRASVLHCLLVKVVILLLHSSFPCDELSPAAEYLLTEGGLIQNIYDTATSPNPGSSVACSGLRSFNQNLGDAINRAKKAGIPNQKLLAILSADNTWTELEDIIHLYNLKHRPQMQHDFNDSSVVSSIRNDSHGFNDSEEWTDASTKFAEMDATSSAKQAFSGFSSPFEPNMQRFSDFEGQFDDTPDEDEFRKLCSERANSSSCAGISFETSPIKWPGEAEKTSEKASEPPSVVASTYPQQTNGNQAFLEQEEGDGEWVWPTVPPLGETEVVTQTGHRPENNWVDETAPDFSHLDMAPPKEDDMWADFSSFPTISPTAAANSASSSSSDAWPGSDIHLQGEASDWPLNNSHESKASDPVMVGLAASISHPGDSSEA
The following text describes a protein:
Function:
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MENFRKVRSEEAPVGGGADGGGPGSGPFADLAPGAVHMRVKEGSKIRNLLAFATASMAQPATRAIVFSGCGRATTKTVTCAEILKRRLAGLHQVTRLRYRSVREVWQSQPPGPSPSQKPGDPATSLSVVKNVPSLAILLSKDALDPRQPGYQPPNPLAGPSSQPSTPTSKRSLGEPAAGEGSAKRSQPEPGAAQED
The following text describes a protein:
Function:
Fallaxidin-1.1 shows no antibacterial activity against Gram-positive or Gram-negative bacteria. Does not inhibit the formation of NO by neuronal nitric oxide synthase. Has no effect on splenocyte proliferation or smooth muscle contraction; Fallaxidin-1.2 shows no antibacterial activity against Gram-positive or Gram-negative bacteria. Does not inhibit the formation of NO by neuronal nitric oxide synthase. Has no effect on splenocyte proliferation or smooth muscle contraction; Fallaxidin-1.3 shows no antibacterial activity against Gram-positive or Gram-negative bacteria. Does not inhibit the formation of NO by neuronal nitric oxide synthase. Has no effect on splenocyte proliferation or smooth muscle contraction; Fallaxidin-3.2 shows antibacterial activity against the Gram-positive bacteria E.faecalis (MIC=100 uM) and L.lactis (MIC=500 uM). No antibacterial activity against the Gram-positive bacteria B.cereus, L.innocua, M.luteus, S.epidermidis, S.uberis and S.aureus, or the Gram-negative bacteria E.cloacae and E.coli.
Subcellular Localization:
Secreted.
Sequence:
MASLKKSLFLVLFLGLVSLSICEEKKRENEDDAEDENHEEESEEKRGLLDFAKHVIGIASKLGKRSEEKRYHPFGKRSEEKRYFPIPFGKRSEEKRYFPIPIGKRSEEKRYFPIPIGKKKKKK
The following text describes a protein:
Function:
Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus.
Sequence:
MAWAGNIGAGGDFGSQNTWPDGTTITNHGTGSSKRASNQGYNTSSSTGGDGGRVNLKDLTAQASNVVIIGIVIAKQKPRQVQSKSNPGTDRSVFGFTLRDSPVDFINASCWGSSEHVLALSNKFRIGEIVEIKNPQVQTKSHSEIEERCRPWTPSAFQLNVSERYSTLNLYDGWHAEPFGTLQHMPIRESSDYYTLGDVLANGRNLHGEHINLLTLVKKVGTPKDIVTKGGRETKRCEVSFFDETCSSFSMVIWDEEVIDLVQQWQAKETVIFAVDVVAKYDDFRNTMVASVDSKSIFIINPDTREAHSLYKFGQSSTADEESAEETKDSIDLQSIHDVYMVDELKAKMCDKQSVMMQSDYGIVYAFLSAYDLDGPTSAVLSMRCTSCHKRVDKETGTCLNSNCSAAITDQSQAILNYDLRVNLSDLSGTINGVYVGGYVAEQIIGKSAEEFSKCSEDELTGMKWQHLLERCKVYFKIQERPGIINGSSSFLKILQCGRAEPDEVLKNIKV
The following text describes a protein:
Function:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
Subcellular Localization:
Nucleus.
Sequence:
MKSLLKNISLNLDNESERQKILGDLILGIDNDEKLQNVIGEILPFATDNDRQLRTASIIALEFINNNFDIKSVKVAILEMATAKLTDSATLFTACKIVKQNFQYASEEYITTIFETLITVDLRSNLLKHRLEAYSLLEMLVNNPALKIAPTQEIIDRFRKFCGYEQDPKCLDYIFKLFPIFSKRILPDINEQMRAQLYDVVSVFYPITARPELSHDLNTTLSLLPEYTEDLCELVSTKLSNALADTRSAVYQSLPDLLIREAPEQSVGNIVVSFAKSLSDYFANGSTDATQEVVDSAVKALVHFVEISKDSHQMLLQSAMQNWIPTIINSTESSTIRAYSIVAWSLDTVLNFSPIALVPLSATAEESLAKKDEARIQAILASVVEFLKFTHVVEKEMEDIKGIFKVAIVVLSSGEYSQNCIVSALVVLREISNKSNFPDNDEVVKLALKYAKVQSFSAQLLCSLADRQIQYEQQLNNELVSKLVSAISENNTEIIGDDKPFSTISEVVAFASRLSVSPFFARFLLPAIAKGGFVKELLKCILPLHEIPSETCDSILSALNALQNPHKDAVLSVAIRSPRGFLLDAMIKYTRISDLLLFAAFPSEVPSRPNLTSDLAKFAYGAKTSNYFEGFHPPAASLCFRNEITSEFCAEDIPILLEMENFFDGATGAVFNKFDLLNERFMYNDEYKTYLWKPFYRNLFDKPKILCKLCLLCPPDFFLSVLSEFILLLPSFIENDTKGGLDLTIFALMSLNKRDQIAMISTMSTLVVAVCDVVKNGDNYERLDACKVLRAMTAQLPTDACVPHKRLVMKTLNVALDDNKREVRNAAALARVDWSKIE
The following text describes a protein:
Function:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Sequence:
MNQEEGEVNQLEQHEKVVKYIVKNTPFGQANLVIKDLCKIIGNINPQHSIMLQALRDHNEEHLALFKGQSTQILTSVLNSQEDFYVDQKNNETIQVDHEKLEVISRSQVELPSDPELNQLRDALEQQLNLYLTQQFNEKVCGAYVMYQGDASDFTFYIGITAKTINLPNFFCGSWISTWEFTKTQLKGDLKVQAHYYEDGNVQLKNVNTFSEGINVDLSTASESAKQIIHTITRLENRHLAGMDNLYNSMPDIFFKAMRRPLPITGTKMNWNENVHKLVANLKQ
The following text describes a protein:
Function:
Required for the synthesis of yeast cytochrome oxidase.
Miscellaneous:
MISCELLANEOUS: Present with 6840 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MSKYAWYTRVTDTLHRLTVLTLVGGTLYMSGGLAYTLYMNGKKYEQQVTQQKALEEDNQQLQSPTAPPTE
The following text describes a protein:
Function:
Required for mitosis progression. Promotes the nucleation of microtubules from the spindle (By similarity). May play an important role during the embryonic development and differentiation of the central nervous system.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to intron retention.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MQENLRFASSGDDVKIWDASFLTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVDLNSTSMYLASGGLNNTVNIWDLKSKRLHRSLKDHKCEVTCVAYNWNDCYIASGSLSGEIILHSVTTNTSSTPFGHGSKQPIRHIKYSLFRKSLLGSVSDNGVVTLWDVNSQSSYHTFDSTHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTSLTKASLSKGSSNKATAVNKRSVPVSSSSGAAQNSGIVREAPSPSIATVLPQPVTTALGKGSGAAQDEAGLARSKSTDIFSKETDAGKSQDFSSFDDTGKNSLGDMFSPIRDDAVVSKGGDESIGKGDGLDFLPQLNSVFPLRKNAGASSSLVLHSSPLNVLMGSSGKEENESHEPSAESKRAYLGKQEPKDAMKQFTKLISSGAEPGILNTCPSSNQARNLEKFEKPEKDIEAQLIHEPSVNGSSTTVPKAASSVTAGVASSLSEKIVDTLGNSRPGAPLTSVQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHIQLNEMHSLLERYSVNEGLVAEIERLREENKRLRAHF
The following text describes a protein:
Function:
Acts as a protein acetyltransferase. Negatively regulates aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9. Acts as a regulator of mTORC2 signaling in response to hypotoxic stress by mediating acetylation of RICTOR, thereby protecting RICTOR against ubiquitination and subsequent degradation by the proteasome.
Sequence:
MLSRLLKEHQAKQNERKELQEKRRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKGSLVW