lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Possesses 5'->3' exoribonuclease activity. Acts as an endogenous post-transcriptional gene silencing (PTGS) suppressor; Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II. Essential for vegetative cell growth and chromosome segregation.
Subcellular Localization:
Nucleus.
Sequence:
MGIPAFYRWLVDRYPLSVVQVREEAPVVVNGVQVPIDSSRPNPNGVEFDNLYLDMNGIVHPCFHPEDRPPPKSYDEVYKAVFVYIDHLFSLVRPRKLLYMAIDGVAPRAKMNQQRARRFRAAKDRADAAAEAEKLRDDFESQPEKLCNPEEINKMDSNVITPGTEFMALLSSALRYYICLRINSDPGWRGIKVILSDASVPGEGEHKIASYIRSQRNLPGFDPNARHCLYGLDADLIMLALATHEIHFSILREDVRVARRTERTSKFENKNKSSSKEGKVWNHEVNHEVPRKKFQFLNIWVLRDYLQHDLKIFGAKMKIDLERLIDDFVFICLFVGNDFLPHVPSLEISEGAIDLLMTVYKKEFAAMGGYLTNSFEVNLERVEHFLQIVGSHESAIFRKRIQLQREMNSHLRDAVEVEQKIGSIWMKSFERSANFLGRSNPNSTASVLKGQVQQGEEEWKEEYYSEKFEVKSEDECQKLKRHAVEKYVEGICWVMHYYYQGVCSWQWFYPYHYAPFASDFLDLKDLEVQFKLGIPFKPFNQLMGVLPAASAHALPLRYRNLMTDPSSSIIDFYPADFELDMNGKRFSWQAVCKLPFVDESRLLAEVKRVEYTLTDDEKQRNSWSMDMLFVHFSHPLTSKIRSFYRRKKDHPKLPKTKLKKRIDPKISSGMNGFIYISDKTIFSPEIFSPIEGMTLITKNKTIFVYYKIPPIQTHISKIPSGVILPNKSISKKDVQPAPVLWHERSMFKRKNLERPLSHAIAGHRLSQLACSLVSNHYRERKQAVNVRKLDKNAINGQCKMQKMLEQRTIHESNGNGNVLGKRKHRGGSRRKKKVQVMSQESGQNTSNLGKRKRGGHGRHKRKRN
The following text describes a protein:
Function:
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.
Subcellular Localization:
Cytoplasm. Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MRDTPLSNCERLFLLKAIKEKKRLDGRQTYDYRNIKISFGTDYGCCVVELGKTRVLSQVSCELVPPKDSRPTEGIVFFNLELSPMASPAFEPNRQSELLVTLNRQLERCLRNSKCIDTESLCVVSGEKVWQIRVDVHVLNHDGNLMDAASIAAISALSHFRRPDVAIQGRDVTVFGPEERDPIPLSIYHMPICVSFAFFLQGSFLLVDPCEREERVKDGLLVIAMNKHREICSIQSSGGIMLLKEQVLRCSKIASVKVSEITELINKALENDKKVRKEGGKFGFAESMPKERITTLKRDEAPVEMTDVKETADDIVQRTETTTETVPSPILVATGTAQIGEGIVNSWGLDEDEDDELQTEDRKTDEVVVITDSEEEEVVILNDQKSKKTSKQK
The following text describes a protein:
Function:
Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MLSRGNTAPMFFRLLSKFPQGFSFCFAYGSGVKQQLGYESVRSKRNMIDLIYVVDNAHRWHTANLDQNFEHYSSMRLLGGGLIAKYQESFGARVYFNTLVQIPEEDVIIKYGVVSTKDLLEDLTDWRCLYLAGRLHKPVEIIRNASSSKIQNAMEQNLRSAVHAALLLLPEKFTEFELYRAISNLSYSGDFRMIFGENKDKVNNIVRPQLENFRNLYSATFEEFRGCLELPIAGSDNQICTQDLAEPTILAHLNGLPKWPIRLIVERQTSGRYRQDTEDILIGVSRATNYQSIVASCLRSIVWSSSVWQSIKNIPTAGFVKSVRYSWAKALKTFS
The following text describes a protein:
Function:
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Sequence:
MAKSPSKPAQIPSVGSSASAHELRGTGDELHQKAGGSHPQLTTNQGIPVGDNQNSLRATPRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFELTKSLSQYTTAKLLTEVGEKTPLFTRFSTVAGGAGSVDTPRDVRGFAVKFYTKEGNWDLVGNNIPVFFIQDAMKFPDLIHAVKMEPDRGFPQAASAHDTFWDFISLTPESMHMIMWAMSDRTIPRSLRMIEGFGIHSFRLLNENGDSTFVKFHWRPKLGLQSTIWDEAVKLAGADPDFQRRDLFEAIQKGDFPEWELGVQLFTEAEAEAFPFDHLDSTKVIPEELVPLQIVGRMVLDRWPDNFFAETEQVAYCPANIVPGIDFSNDPLLQGRLFSYLDTQLSRLGGPNFHQIPINAPKCPFANNQRDGHMQMGVPKGRVAYEPSSLQADAPREALRGFPSHATPAEDGAKGRVRAESFADHYSQARMFFRSQTAPEQAHLASALVFELSKVETAHVREAIVGHLRHIDEALAKRVADGMGMTSLPPAPPAAVAPTDMQLSPALQLIGKMKDTLQGRTVGILIHDGSDAAAIKAVRKAAEAAGATVKIVAPKLGGAKLSDGKQLAADGQLAGTPSIVFDAVAVLLSSEAAKALTRESAALDFVSNAWAHLKAIAFDDGAQLLLKAGNVGKDPGVVDAADTKAFITAAKTRQWAREPKVRMLA
The following text describes a protein:
Function:
Essential for both cleavage and polyadenylation of pre-mRNA 3' ends.
Subcellular Localization:
Nucleus.
Sequence:
MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDYAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRVWQRDQRDMRAIQPDAGYYNDLVPPIGMINNPLNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHSGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLLVSGSKDSQQPIKFWDPKNGQSLATLHAHKNTVMEVKWNLNGNWLLTASRDHLCKLFDIRNLREELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWNVGVEKEVGGMEIAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPGMSEDGMEYDDVEPNNLAIIPGMGIPEQLKMAMEQEQMGKEESSSVEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPLMPPSEGVPDRKEEKMSDEKKKNQAEIEQEMAALQYTNPQLLEQLKIERIAQKQAETPGQLQGLPSPLGGPSHGPSTFQAPGPQPQQTQRFQQPHPPQQMNVQHGPAGQFLPQGSQAAPGPQNFMVSGPQGVRSQEMHPGASRLPVPHGPIGAQGPPVNSGPQNQLGPQGPSGPRPIQGMSSHHSMQGAPGPQGPLMGVTPREGPMPHGLRESSGPNQGMAIVHPAQDMRGPSGAIVGHGQDMRSPMELRGPSDMRGPQEMRGPADLRGPNDMRGPQDMRGGPDMRGPQDIRVPMDMRGPQDMRGPHDIRGPQDMRSPSGMGGPQDIRGPPDLRGAQDIRGPHDMRGPQDMRGPSDIRGPQDMRGPQDMRGPHDIRGPTDMRGPQDMRGPPDMRGPQDTRGPPDMRGPQDLRGPPDMRGLQDIRGPMDMRGPQNMRGPADMRGPQDMRGMPDMRGPQDMRGPPDMRVHQDMRGPPDMRGPQDMRGPPDMRGPQDMRGPPDMRGPQDMRGPPDMRGSQDMRGPPDMRGPQEMRGHPDMRGPQDMQGPPDMRGPPDLRGPQDMRGHPEMRGHPDMRGLQDIRGGPDLRGPPDMRGPHDLRGPPEMRGHHDIRGQPEMRGHQDMRVPPDMRHQDMRGPQEMRRPKDMRASHDMRGPQNMRGMPDHGPQEIRASPDLRSPQDLRNLQDSRGPADIGGPQDLRGPQPGLSQGNSQGPHSQQNTARASHPAQQKAPLLGDGPRPFNQSGKGQAPPPLIPGLGSQSSQGRGHQGPSPNKGDIRGPPNHQLGAQPDRRREQSPDHGPFHGGQEWGDSRDNRGPSDRRGPHPDSHERPEDFPPDDRYGPRGREFDGRGGGSSSQDDKWRRGGPASQFPSNHRDFPDRENRDSNRWEGRRHSEERYNRESEDGRLRGQRDEAFHRAGPQRREGRGSRGSEGFANPEEFGPDDNFDSKDEPVRGRDGGRGRGRGSQREGRKGLLPTPEQFTGSDRAPNHQSRESRDAGPDHFPNSPRRDIPTPDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTPDHRDMDTAGGAPEEPVKAARESSGPSSRSQRPSRSSSQEQEEGSSRGTRGTGSWGRGGSRANSNMNSSQSWRGGPRGSSSSSGGGRSR
The following text describes a protein:
Function:
Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.
Subcellular Localization:
Cytoplasm, cytoskeleton, stress fiber.
Sequence:
MKMADAKQKRNEQLKRWIGSETDLEPPVVKRQKTKVKFDDGAVFLAACSSGDADEVLKLLHRGADIDYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGHGAHVGAVNSEGETPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQASYDVNIKDFDGWTPLHAAAHWGKEEACRILVENLCDMEMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKREKKSPLIESTANMDNNQSQKTFKNKETLIIEPEKNASSIESLEQEKADEEEEGKKDESSCSSEEDDEDDSESEAETDKSKPTASAPNANSSSTQTASVAVTAPSIPTGQATPTSPIKKFPTSTTKVSPKEEERKDESPASWRLGLRKTGSYGALAEITAAKEAQKDKDSAGVMRSASSPRLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIEEKENRDSSSALRTSSSYTRRKWEDDSKKNSSINEGLGSYYKSCSFGRRQDDLISSSVPSTTSTPTVTSAAGLQKSLLSSTSTTTKITTGSSTAGTQSSTSNRLWAEDSSDKEKDSVPTAATLPVAPTVVNAAASTTSMTTAGTVSATSEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDEPYQRYRPVSTSSSTTTSSSSLSSIGSSLYASSQLNRPNSLIGITSAYSRGSTKDNEREGDKKEEEKEEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGTNKKESQADALSRYETGSTGTSSSDRYDSLLGRSVSYGYSEERKPYCSRLEKEETTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERYADRSLLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MASPFSSWISMEEQGFYSKKPYTYTNSEHIDLTLKLSPCGQNAEEEEEEEEEEEEKMVEKGLVRFGDLQTMRRVKTWKRLLMKKMRMAAAKEAEKSLPVSPGGGAQTLPHSIYNSLKTFANPCGDAWHEGAMQEMTLWPSETMIENERPAKKLKHVNSYQESDAMPSVITTGDGTITGKRTVCIVCVCHGSFPSPTEFVMHAGGKEVADPMKHITVCSDSFGINGDGAAFITHPF
The following text describes a protein:
Function:
Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.
Subcellular Localization:
Chromosome.
Sequence:
MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAEDGETVAREELNEDGSQVKRTGGAEDGAPAPFIAVQPFPALLDLPMGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFVDKQLQVKAVTCGPWNTYVYAVEKGKS
The following text describes a protein:
Function:
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MAPQTKIDRSFSALTPALSEWIIDAVDAMGFVKTTPVQHAAIPMFMKNSDVVVEAVTGSGKTLAFLIPIVERLLREDAPTKKHHVGAIIISPTRELATQIHTVLSSLLKFHAPSAAMLEPDDEDTDMEDADTPPKPTFPPGTLKAVPQLLLGGSVTPAQDLSAFLKKSPNILIGTPGRLLELLRSPHVHCPQSSFDALVMDEADRLLDLGFKEDLQKIISRLPKQRRTGLFSASMSEAVDQLIRVGLRNPVRIAVKVKARATGEDGKIEDKRTPASLQMSYLVTPPSHKIPAMKKILSSLQPQPQKSILYLSTCFSVDYFQHVLPEVLQGYDIVPLHGKHPDKVRRKNFNKFVDSVTPSILLTTDVAARGLDIPSVDLVFQLDPPSDPKTFIHRCGRAGRAGRRGLAVTFLNPGREEDYIEFLQVRQTPISPLTTPEITVTDEDAKAVTSKIRKKVREDRALFDKAQRGFVSWVRAYSKHTASSIFRIDDLDWTELGNAWGLLTLPGMPELKKWQGDKRLGIELDLATYAYKDKAREKLRLEELERDKEEGTKKKQHKKEDREKSAWTEQKESKATKEVRREKKKSKREHERLAKMTDEERKEEDRVQAMIEQMRKKVAKQEAEDADFEGFSD
The following text describes a protein:
Function:
Requires L15 for assembly into the 50S subunit.
Sequence:
MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
The following text describes a protein:
Function:
Enables the bacterium to metabolize sucrose as a sole carbon source.
Subcellular Localization:
Cytoplasm.
Sequence:
MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGLLNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDSHGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPADSTDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRTAYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQLQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDDKLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSINFDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVFSGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN
The following text describes a protein:
Function:
May play a role as a negative regulatory factor in CD4-dependent T-cell activation.
Subcellular Localization:
Cytoplasm.
Sequence:
MGEIKVSPDYNWFRSTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFFQQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAEYTHKSPRVHSLILCNAFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDIHLLQFHGTKYAAIDPSVVSAEELDVQKGQLDLSQEEP
The following text describes a protein:
Function:
Probably participates in deamination of adenosine-34 to inosine in many tRNAs.
Sequence:
MVASLSLEQRPGGPLSGVFCLCDPAWLPTLNSPPRKAPRKKHFFLCRLRKPHTASSIPAAEETQQRKKPRPRRRPRASLHFPVPRCCLGPRSKHVPPEAWPRTLSSGQQRRRNRAGMEATGRRGETAAEAKEALENGEVPVGCLMVYNNEVIGKGKNEVNETKNATRHAEMVAIDQAIDWCHKQKKRMEEVFLHTVLYVTVEPCIMCAAALRMMSILHKMIQVPVTLRSCCGSVLNISSDTLTDTGEPFQCIAGYRSEEAVEMLKIFYRQENPNAPKSKVRKKECSK
The following text describes a protein:
Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence:
MDPNCSCATGVSCACASSCKCKECKCTSCKKSECGAISRNLGLWLRLGGNSRLAWSACFWGTPFFAPVGHVIPSPGFLL
The following text describes a protein:
Function:
Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation. Inhibits root growth.
Subcellular Localization:
Cell membrane. Secreted, extracellular space, apoplast. Endoplasmic reticulum. Golgi apparatus. Note=Observed in a reticular pattern and a perinuclear ring. The precursor of SCOOP15, PROSCOOP15, accumulates at the plasma membrane and is proteolytically cleaved to release the SCOOP15 in the apoplasm.
Sequence:
MSKEKSYVIALLLSLLLCLSFQVGVSEANYNAVTTRYSDSPRCANGSSASPPTRHCPRGRPRPPTPRVAVHSNSTKGKGP
The following text describes a protein:
Function:
Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.
Sequence:
MPSNPSFNWSKLQNVYYNIRTCYDEMDWSIDNLYSNYLVSLSPNTTLIAIASKSAPHPNLIEIYSNSGHKLWSVVYNSTHNDYIQSFHFTSDEDLIIVLNNGRYRHYYDLIGSFNEYNFVEDLVTMDNISQRHNTGDKIDANPDNTRIITNLENNQTEEIIKIIEVKTWNQFLVVRLESKIIVSDLDSFTNYAISLASYSASDFECFSIQAKTGTKKAVTIQLGYRKSILSIDVDFDLASYEILDQELTDGPFSSIAISPSGQLISLFNQQLKKIFVISNKFDQILLDYDTSNESSDPYQVEWCGNDAIVLSFKDEIKLIGPGQQSISFFYDIEDDDEFDLDNLMVRKDNKNTDYKKFDDLLFTIPILQTSIDGLKIVTTNKVQFLSRVPETSVEMYQVGSTAPSSILADCIDKFSANASKADSNISLLRADNTLLKAMEDCLQVALDEFSPDWQRRALKAVSFGKVYYDDYFDSDKFVSVVDIIKVLNLIRSPELGLFLTYQQIEKIGGWEEVIKMLLRRNHHDLSLDIIDKLNLGNAKPLVYIHWCCYKIRKELDMSDIDLFKLVSEKLISSTKTRVNYISTEQISETAHEEGREELCKFLLDLEPSVIKKIGKLLNFDETELALIKSFQNGNYDLSTLILLYLQDNLTTSQFFKILSQTESVLKKENSTKQTIQKLDIDVKSEYMQVTGEVVGHAWEESIAKNVSPRLLETYLKHEDRVNELNIFKIQQFKRDPELHKDNYYESYKSVLTKAINRSTNQRISKALQREIQVLELQKKLSETYLTDFYQEKTLMAILKRMIAMNQIKPAKKIVANFQLSVEKFWYLVLNTLMDRREFDQLYEFAFGSSDQTSGNSPIGFEPFAELGLQKNAPQSHISTYIKNSNKYKYEEKISMFIKNDDYESAALEAFRNKDIDILKSLLQKIPNSNQADIQVVNSYIQQLGY
The following text describes a protein:
Function:
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRDNESDLCESNCHLNSGESPAVSAVMFSAGVLGNLLALVLLENRRRAVRGTMSLFHILVTGLVITDLMGTCMISPVVLASYSSNLTLIALGGSDNRIVCYYFAFAMTFFSLATMLVLFAMALERAMAIGHPYVYEKFISKRCGLVTFPVIYSFCIFFCLFPAMGVGEYIQYCPGTWCFINMRGQHINGSTGNIYSTLYATLLLILIIAVLTCNFIVIVSLVRMHKRQKARRLVTKRERMSMSEEIDHLILLSLMTIIFFICSVPFTAQVYMNRFSPDRRNDKRDLLALRFISVNSIIDPWVFTVLRPSVLRLIRYVLCCQKPFKIKEIAKSPSLTSRLSNTKLTIVDKKYESSQKSQPDDHDKIPPGENT
The following text describes a protein:
Function:
Is involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MILHLSHSMTEISQIKLLGNIASPYTSRVQFVLNLKSIKYELIEEDFDDKSELLLTSNPLFKRVPVLLQSNKPPILESLIIIDYLEQIYPDVYKLYPYDHADQAVLKFWAYYIDTEFFPLYGRLRKTPDKEGKEVLKKQIIEKSHVLENLFVKFSNGKPYFGGDDVGYLDVVLGCFLGWTKFVGNHNNFKIFDEVRTPNLIEWSKRMLSHESLKGVIPDQEIHIDFFKWLTKARPPPKAT
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MEATTKNLVSSSPSFPTKTHLKNGFSSPSSVVMLHEQTATPVINSRHLASLSRHFPASVLSQEPREESRPPPLSHSLREDRTSQQLTLERRQFDGLVSSREDEKFEQQLLQSAGLWNLLLSPSPTVVSPLEDAVALAHKALSASKQAALLAEDSETAAPPTSSSMSLEEGTVVRSKKLLERRARNRRAPKPNGLDNESSYLPQKSNAKKKMRQGFDNDDSLQLFLWGPETKQLLTAKEEAELITHIQNLIKLEKVKTKLESQNGCEPTIAEWAEALGISGPVLKSEIHRGRSSREKLITANLRLVVHIAKQYQNRGLNFQDLLQEGSMGLMKSVEKFKPQSGFRFATYAYWWIRQSIRKSIFQNSRTIRLPENVYMLLGKVSEARKTCVQEGNYLPSKEELAGHVGVSTEKLDKLLYNTRTPLSMQQPIWSDQDITFQEVTPDSGIETPDMSVGKQMMRNHVRNLLNVLSPKERKIIKLRFGIDGGKQRSLSEIGEIYGLSKERVRQLESRALYRLKQNMNSHGLNAYADLLV
The following text describes a protein:
Function:
May function as a sugar transferase.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNRLFFSKIALWLLDFLTFNISFLLSLFVISYYHNGYEKYLPIYEIDDRTYIHAVLAGICVGWFAIRLRHYTYRKPFWFELKEIFRTLIIFAIFELAIVAFPKLYFSRYLWALTWGITFLLFPLARVLVKKFLIKSGWFLRDTIMIGSGDNAFDVYNALRDEPYLGFQVTHFISVSNISNNVKELNIPILNSMSSWTSVTKKTDQFIIALEDDEEVDRNNWLRYFSTNGYRSVSVIPTLRGLPLYNTDMSFMFSHEIMLLQMNNNLAKLSSRILKRTMDIVVGSLAIIIFSPVLLYLYFAVKKDGGNAIYGHPRIGRNGKTFNCLKFRTMAVNSKEVLDELLRTDPEARAEWEKDFKLKNDPRITKIGAFIRKTSLDELPQLFNVLKGEMSLVGPRPIVIDELERYEENVDYYLMARPGMTGLWQVSGRNNIDYNTRVYFDSWYVKNWSLWNDIAILFKTMNVVLNRDGAY
The following text describes a protein:
Function:
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
Subcellular Localization:
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Domain:
The FYVE domain is involved in the binding to phosphatidylinositol 3-phosphate (PtdIns(3)P) which is required for the association to endosomal membranes; Both IUM domains are necessary for efficient binding to ubiquitin.
Sequence:
MSWLWGSTTNPQFEELAEKACSPLNLPYPQSEDIATALEVADMIRSKAIQPKMAMQSLKKRIASKNGRVQMYAIGLTDTCIKNGGDHFLLEVASKEFVDELSNLIKATTTSPEVKQMLIKYFQQWALAFKSKSELSFFVEVYNELRASGITFPPPPAPVPSHLLTTTTAPAWVDSDACMRCRSAFTFTNRKHHCRNCGLVFDQACSSHSMPLPKYGITEEVRVCDGCWAKAGRNKADAPAPAVPGRTPRSRADLDADLQRAIELSLAESQHSQNRHHSHFTPSEPPLAHGTVEDEDEQMRLAIEASLRDMEARPSAPAGLGEAPEPEYRPLPTFDLSPRENETILTFSNTMDQMAAYGERDLRRFPHAHVLAEQANTVGGRLRRNVEEKSTKQQMLMEMQDKLSQAVNLYGQILDGQQAYAAKRAHEEQARRYQQQQSYYTQQYQPQPQLYGQYPPNGYQAFVPPQQAYQPPQPQPEAQAQHAPSLYPTMPYTTPNFTSPPQERVYPQQSHSSPYSQWSPAPSHVQPGLARQASVVVPPVSSPVPAGVQRQASMTYGAPIPVAEQSQRQQQQYASAPPFASGAAPVDIPSAPPPVNLSTHPNSPQRHSYIPSHPQTQTQTQYESQPQEIPSQQDMQYGASAPPPDSLGSYVSEGTVGSAKSGLEQEHAASQIQPQPQPQASAQTQTQSQSQLQAQPQQNQYAAQTQLPAGMYNAASFPQPLPPTIFPDAPVEAPKGLEKEEKEEALLIEL
The following text describes a protein:
Function:
Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNTFRKGLDLLLGAICCLVLAIMVGIACWQVVSRYILGVPSTLTEEMLRFLLVWVSMLGMAFVAGQKQHISLTLLLDKVSPTIRGWWDIILQVIFIAFSIWVLIIGGLKISAISMLQISPALGIPMGKIYYALPCAGVLIILYGLLNIVDALKAIHSATDTTEHTLEKSHD
The following text describes a protein:
Function:
Plays a role in vesicular protein sorting.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MSKEAEAPAPELKYGQLPSEEIQQKVVREVLEKVNGLAYLMRRNFDNNKIDDALKYATLMLEEMKINTLSPIHYNELYQVVLSELTILKDYFNDSNFFTDRRIAELYEILQYTPSIVARLYLLFTIAPAFVKRGHAKANDIMRDLIEMARGVQHPTRALFLRHFMLHILKEILPDGQREGGTIEDTLHFILENFKQMNVLWVRLEFSLDTKTIEERKLQRSQLKQLVGHNIQRISDLRGLDVAHYKEIVLPCIVEQTKACGEPLAQYYIIESITQVFPVEFHIETLDILFNLLQHLDDDVNTLALVTNIIQRLQTFCRSDSNAINTVRLVAVQIYSLLHADQKFALEDTLDMLGTLLNFTLEADASNFDNVNAIFKLVEGHIEDIAGESRLDSVSVSRKLCFFLVTPLREMKDASMIFDLEYFPILVNRLRFLDRKAIALEVCKGFARTEAYITDVDNMKAFFNIEQVLLKRADDYEKDPDGEPLSVALSNVGRVFHLIRDRKDLDNTFSLLTSISAALQTFDPEVKEALYLPFGEDLLRVAVEINQTQGCQTTVRGVLQQVYILLTQNDPPAIPSFWLFVEAALISDRYGTEGITTEFFTNALRIWKEGMIDSNIRFRMLLSMIRTATQLLNVTPNTYSSITSELCSCAGGLLAKEQQAEAHLLCAHMFNVDRKGAGNEDDNEEEEDDGSAFMNPMKVKNCLVRALKAASQMMDKKDMLPWFYKVLAEAIYFIEKGVDIPIDWFNALTNQIDQEHQNLGSDLENKLTEQAKKFYINTVAHKNKVIQTK
The following text describes a protein:
Function:
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
Sequence:
MHMRLFSKFKLHGSSAASEEVFGGKFSYTSAVADFYIELGDAHKIWKPRDVVTGEVVLTLRKPLRGVSLRMSLEGNLRVQTGSGATSRLKFQRTLFSKSSMIYGVEQPEDAEQEGHGLTRGDHRFPFRMRVPSKNIYTSIAFEKGSISYAVGCVLETRSGAQRLSSCSRQISVLVPVDVSLLPKLRPKTVVLQSPQLLRSAKANYPEHDTASSLTKRTTASANSNSSVTTVCSSKTVTISVDLPESGYVIGDTIRIKVHIQHYKEYRNSAGLIATLVRICRVHSTGTDDPMETFRKDICQCVAPLYVEPETHTCSVGMNLNVPLDAFPTLVVPNQGFTFQYYIEVLANLSSKNIVYTESNRVIGGSGMADIPMPGSKLHPVKKISMLPLKLQGPLGKQDTNIDESLIFFQDMVNVDKLKRLRNVTGTSIEVVIGTHRNNSVQQARQSCPGSPVGGSDSTMMSEQSAAGTSLPSSVLDIYDQLANRLSSSVGDQLLRYGMSPDSGPHSANDELPRYTPNVDYMVTEDKRELEQRKLKELESEPSVEEEQ
The following text describes a protein:
Function:
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Couples electron transfer from reduced ferredoxin to NAD(+) with electrogenic movement of Na(+) out of the cell. Involved in caffeate respiration.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
METKEKVQIDWKVVFKLGLILFVISAVAACALALTNYVTAGTIEEMNVQTNTVARQEVLPKAADFEAVPAKDVEKIASEIGMEKPEELLEVYIGKSNGEVVGYTVKTGPTSGYAGEVQVLTGISADGVITGITIIKSNETPGLGAKASGVWNDQFTGKSAKEELVVVKGTTKEGSNEIQAITGSTITSKAVTSGVNMSIQVYQNLSK
The following text describes a protein:
Function:
This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
Sequence:
MENMTPLYRQYKSIKDQFSDAILLFRLGDFYEAFEEDAKIISQELDIVLTSKEIGKGKRIPMAGVPYHSLDSYLSKLVQKKYKVAICEQVEDPALAKGLVRREVVRVITPGTLVEDTLLEDKNNNFLSSIYALNREYLALATIDVSTGEFFATEWRGKDAEEIIYSELVRLKPKEIILPFSLKDLLSELLSDLKREVDPKITLLEDSYFEPSDHQISYSEPEENYPLAEKSINGVLSYIKEVMFTIPTHIERVEFYKPQQYLILDSTAIKHLELLETVREGQRRGSLIWVLDKTLTSMGARLLKKWLLQPLLNVNAIKKRQEAIKEFLDKDPWRREMEEILKEMPDLERINSRINYNTATPKELIYLRQALSFLPLLRKSLEKAESNRLKELKENLPNLEPLYEELDRALVESPPSHIKDGGYIKDGYDPNLDELRKLLRESKDWLINLENRERERTGIKSLKIGYNQVFGYYIEVTKANLNLVPSDYIRKQTLVNAERFITPELKEWENKILHAEDNIKKIEEELFQNLRKKVIKHSKDITTFAQTIAEIDVYISLAKAAREYNYVCPQITNDYEVIIREGRHPVIERMLPPGTFVPNDAYLNKDKFIDLITGPNMAGKSTYIRQIALIIILAQMGSFIPAKEAKIGVVDRIFTRIGAWDDISSGESTFLVEMKEVGNILSHATERSLIILDEVGRGTSTYDGISIAWAIVEYIHNKIKAKTLFATHYHELTELEKELKHLKNLSVAVQEKGKDIIFLHKIAEKPADKSYGIYVAQLADLPKEVIERAEKILFELEKGREIKKKEIVQLPLFSEITDSKLEKLKNEILSLNTNELTPIQALLKIHEWKELIK
The following text describes a protein:
Function:
Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MFCLEDQVVLIAGGSQGLGKQFGQKYWDESRHSKIILVSRSDVKLRNAITDITGGRQEPVELVMPEVAASEPSASGSSAINLSKSSNHAGFESELRSNSNRSSSSLKESTNVVTHLTTNAADSRIVYIACDLSDPDAVERMFVTLQHNNLLPTQVLACAGGSIPKLFTDLTAKELEMGVKMNYMTTLFVIHKAAQMVPQAHLILFSSSTAFFPFIGYSQYAPAKVSLKALTSILRHELPNTRISCVYPGNFYSEGYVLEEMSKPDITKSIEGSSYPISCEECCDKIVWWLNRGYDDVTTDSIGWFLMSLDMGLNKHNNNSAYWFVQWLIGVIANLLVVPFYMVLCSYQINKWHKQNKNKNTLL
The following text describes a protein:
Function:
Transferase that catalyzes the transfer of sulfur from thiosulfate to cyanide to form thiocyanate. May have a role in the detoxification of cyanide to the less toxic thiocyanate. May also be involved, directly or indirectly, in the transport of the thiocyanate produced across the membrane from the cytoplasm to the periplasm.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Domain:
The catalytic reaction induces conformational changes within the rhodanese domain, as well as in the transmembrane alpha-helices.
Sequence:
MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLSVLEQSGLPAKLRHEQIIFHCQAGKRTSNNADKLAAIAAPAEIFLLEDGIDGWKKAGLPVAVNKSQPLPLMRQVQIAAGGLILIGVVLGYTVNSGFFLLSGFVGAGLLFAGISGFCGMARLLDKMPWNQRA
The following text describes a protein:
Function:
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular Localization:
Nucleus.
Sequence:
MHSSTQRTQQVQSQAGPSSDSNARKRVGVNASSDAASFVYNPRQDARDRRKVRSDYRALIAKAEESKRDSSLKPSDLVDLIAKVDELHERVVAPSESILDTKTLTSMSEMGARMAKKMKLNADAFDTHEFMSRLARYLGGQAAPVRRAGNIDDDDEQVEIDINQWQWSKLGRLSASLSKRAVTMDFLLGPLEIAPKQRRTITQRRQDDTPAERTAPRALQQQDLQDSAGRESTSAIRKVATLLQQQGPAGVCLFRFAVDPESFVNTVENFFHVSFLIKENRASLKTDADGNAVLTIATPPTEDDEQVDTDKPEHVGRSKQFIMEIDYPTYLESIQLYAISESVIPTRSNRVNSLSGRLALDKVRQ