lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Regulates myosin phosphatase activity.
Subcellular Localization:
Cytoplasm, cytoskeleton, stress fiber.
Sequence:
MSGEDGPGAGPGAAAAAARERRREQLRQWGARAGAEPGPGERRARTVRFERAAEFLAACAGGDLDEARLMLRAADPDPDAELDPSAPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIASVNSDGDLPLDLAESDAMEGLLKAEITRRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLADEEVLSLLEELARKQEDLRNQKEASQSRGQEPPVPSSSRHRRSSVCRLSSREKISLQDLSKERRPGGAGGPPIRDEDEGEEGPSDSSPAESRTLNGISSPPPSSPQSPTTPEEASFPRRFGLQKTGSSGALGPTGGRAAEVASRAGLQRSASSSRLEGTSTQAREPRLARVTPTPSRKVPESSAPILEPESPGSPVKPNVPVASAAPPADSRDRRRIYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGKASEPEKSCPQSLDPSRRPRVPGLENSDGPAQREAPDGQGQGPPAAREHRRVGKERRGPAEGEEAEPVDRGPESRYLVGRKGLGLSVGLWARPLTPRLPHPSTPEGGPSSRRQRDLNPEPEPESEEPDGGFRKLYADLRSENERLREALTETTLQLAQLKVELERATQRQERFAERPALLELERFVSEGGGGGASCVSSLPSPCGRVRRAALPF
The following text describes a protein:
Function:
Part of the type VI secretion system (T6SS) specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection. Forms the spike at the tip of the elongating tube probably formed by hemolysin co-regulated protein/Hcp. Allows the delivery of the TseL antibacterial toxin to target cells where it exerts its toxicity. Also acts directly as an actin-directed toxin that catalyzes the covalent cross-linking of host cytoplasmic monomeric actin. Mediates the cross-link between 'Lys-50' of one monomer and 'Glu-270' of another actin monomer, resulting in formation of highly toxic actin oligomers that cause cell rounding. The toxin can be highly efficient at very low concentrations by acting on formin homology family proteins: toxic actin oligomers bind with high affinity to formins and adversely affect both nucleation and elongation abilities of formins, causing their potent inhibition in both profilin-dependent and independent manners (By similarity). Acts as an acid--amino-acid ligase that transfers the gamma-phosphoryl group of ATP to the 'Glu-270' actin residue, resulting in the formation of an activated acyl phosphate intermediate. This intermediate is further hydrolyzed and the energy of hydrolysis is utilized for the formation of the amide bond between actin subunits (By similarity).
Subcellular Localization:
Secreted. Host cytoplasm, host cytosol. Note=Secreted via the type VI secretion system.
Sequence:
MATLAYSIEVEGLEDETLVVRGFHGQESLSNSVFLGQACYGFRYEVQLASRVSNLTAEQMVDKRAELKLYRNSQLVQRVHGIVRAFSQGDIGHHHTFYQLTLVPALERLSLRHNSRIFQKQTVPEILSILLQEMGINDYAFALKRDGVQREFCVQYRESDIDFLHRLAAEEGLVYSFVHEAGKHTLYFSDASDSLSKLPEPIPYNALVGGAIDTPYIHGLTYRTQAEVSEVQLKDYSFKKPAYSFLQTVQGTELDYQQTRYQHFDAPGRYKDDVNGAAFSQIRLDYLRRHAHTATGQSNEPLLRAGYKFDLQEHLDPAMNRDWVVVSINHQGEQPQALQEDGGSGATTYSNQFSLIPGHLHWRAEPQPKPQVDGPMIATVVGPEGEEIFCDEHGRVKIHFPWDRYSNGNEQSSCWVRVSQGWAGSQYGFIAIPRIGHEVIVEFLNGDPDQPIITGRTYHATNTPPYTLPEHKTKTVLRTETHQGEGFNELSFEDQAGKEQIYLHAQKDFDGLIENDHTTVIRHDHHLTVENDQFTQIKHNQHLTVEWESREAVTGEQVLSIEGSLHVKTGKVWVNEAGTEIHVKAGQKVVIEAGSEITVKAGGSFVKVDPAGVHLSGALVNLNSGGSAGSGSGFGGAMPALPGGLEPAVALAPPQTISYQALLQAEQANVPAVKVCPLAAQEATPAVNSITPPPPPPIAPPMAPPQPIMNPQPTANAQPNLGRSTKATPDFPTHFPKSSIGIENELAGLVVAMPANSAQKFGYVKSAQGDALFMLTKDMNQGSYQRPPSLQDGKNYQNWQTHTVELVSYPCEMDDKAAVETRKQAMLWLATHFTTHIDQSNHQPLAPIQSEDGRFVIEITNAKHVIAAGNGISAESQGQTITMTPSGQQATVGVAAKGFGTSATPELRLLESAPWYQKSLKSQFASLTSAENLDDKELAANVFAYLTSIYLKTAELAKKFGIYINEWDPMSEQITPNANGLTDPKVKNAWEILPRTKPSKIVEILSKSDAKAVMKHIKPQLQSRYSESLSKNVFQYFQDGGEVAGHGINNATVGDKHSPELAILFEFRTVPNELQSYLPKTESTTKSEVKLLDQFDPMKRKTVIQQVESLVQNSGDAFDKWYQSYRDSMNQPPVKNAKKIASANQKAQWVKEHNPQEWQRIIA
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MVTAVKYSPLRATYGVRSDQYLEDYDDYRHYHGKLNAKLMSLRRRLQLTTRDTRRYSAKEKYSKVGAAEYQRNRLHGLAMLLHAERDIAYAETLKLRARERGWLKKSERRLLTTRLKKAWRTAGKLLEMTADEGRWVVRAELLVYEKLARVEYLVHGKHSRRKDSDRIAQELALSVAALEYLCTEGEVAAETVATINGRFDYMLRQHAQCFSSAELQAFTAKVVNTRKDDPLLVLLLAHGYELPVEGAAAADGGLQTEVKWRSYNAQIHEPNVARLLNEIKTQDATQVSEHDDPVLKWNAAIDAQRQSMERRQEEGVHYEGEDDQILLTYLQFNYLCATMGRDVALLQPLWVEWQEGRRTARFTKYKQLNHVINNIITHAEEAMGLPGVYSDDELTAYLKLVKVFYRAQLVGRGLAPLYQEEGKHQEALALYAGSMQNLRTAMSAMPRDTAFDPFNILDNVSELQKALESSCRSVAALAEYTGNSSRPAQQYELSLLEKMNTNTFIDYANIYTGNLFPLRPRVMPVSAKPTLFDLAFNYIGCESSAVPPEQTSAAVTPAAETEQPRKRGIFGIFR
The following text describes a protein:
Function:
Initiates the restart of stalled replication forks, which reloads the replicative helicase on sites other than the origin of replication. Recognizes and binds to abandoned replication forks and remodels them to uncover a helicase loading site. Promotes assembly of the primosome at these replication forks.
Sequence:
MDHTSRSSTASANATRMVDVLVPVALDQTYSYKVPRGMELKAGDLVGVPLGPREVLAVVWAENANPDPRLHNRLKEVSEKLDLQPLKPELRSVVDWVANYTLSPRGMVLRMCLRMGENLGPERVRPGVRLIGDPPRRLTPARQRVIAVLSDRLLHGKSEAAKEAGVSAGVIDGLVDEGTLTVEPMPPPPPPPAPDPDFGRPDFTPLQRTAVDTMRALAANGTFHVALLDGVTGSGKTEVYFEAVAEAIRRGRQSLILMPEIALTGQFLDRFAQRFGVRPIEWHSELTPRTRARNWAAISEGSAPVVVGARSALFLPYANLGLIVVDEEHDQAYKQDEGVHYHARDMAVVRAHIAKIPIVLASATPSVESEVNARKNRYQRIALPSRFGGQHMPHIEAIDMRREPPARGRFISPRLAGEIRTAIERREQALLFLNRRGYAPLTLCRACGHRFACTICDAWLVDHRFRQRLVCHHCGFSMPRPHVCPNCSAEESLVAVGPGVERLQEEAAALFPEARTMVLSSDLITSIETMRSELAEIAEGRVDIIIGTQLVAKGHNFPRLNLVGVVDADLGLSNGDPRAAERTWQLLNQVIGRAGREQGRGVGYLQTHQPDHPVMKALIACDREAFYDSEIDLRERTLYPPFGRLASLIISAGDRPSAEGFGRRLVALAPRDERVVVLGPAEAPLAVIKGRYRFRILVKSARGFDLSDYLRNWLAVCPKPKGNQKLEVDVDPQSFL
The following text describes a protein:
Function:
Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a redox sensor to monitor oxygen levels.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Note=Predominantly localized to one cell pole in mid-to-late exponential phase, with a few smaller foci elsewhere in the cell.
Sequence:
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYTLQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPLRWRARGVMTLMFILLAAMLWFVAAPVVTYILCALVVLLASACFEWQIVRPIENVAHQALKVATGERNSVEHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQVSAMVKHRASRLEDAVTVLH
The following text describes a protein:
Function:
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein.
Sequence:
MPSQAVTYTTAAVAAVATGFLAYAVYFDYKRRNDPEFRRQLRRSARRQARQEKEYAELSQQAQRQRIRQMVDEAKEEGFPTTSDEKEAYFLEQVQAGEILGQDPTKAIDASLAFYKALKVYPTPGDLISIYDKTVAKPILDILAEMIAYDPSLKIGTNYTGGVDVAELMREMASAPGVGLD
The following text describes a protein:
Function:
Probable lipid transfer protein.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MESRKIKVMATAIALIMVAMVVDAAGADKGKDKEECTAQLVGMATCLPYVQGKAKSPTPDCCSGLKQVINSDMKCLCMIIQERNDPDLGLQVNVSLALALPSVCHATADITKCPALLHLDPNSPDAQVFYQLAKGLNETVSASAPTGSASEPTSMSSTPGSSAGNNSGRTTSVPGTNHAQSFSKQWLGLEVVAHFFVIFYIFILV
The following text describes a protein:
Function:
Broad range protease inhibitor.
Subcellular Localization:
Secreted.
Sequence:
MPACRLCLLAAGLLLGLLLFTPISATGTDAEKPGECPQLEPITDCVLECTLDKDCADNRKCCQAGCSSVCSKPNGPSEGELSGTDTKLSETGTTTQSAGLDHTTKPPGGQVSTKPPAVTREGLGVREKQGTCPSVDIPKLGLCEDQCQVDSQCSGNMKCCRNGCGKMACTTPKF
The following text describes a protein:
Function:
Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MEHHKHDTFLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTIDNVYGILSLIFWTMTILVSAEYAWLAMSLGRKGQGGEIVLREIIMKLVKAGRLVAFAGFLSFVGVSLLLGDAVITPAISILSAVEGLLLIPGLEGLSTGALVAIAAAIAIGLFSVQHKGTDRVASAFGPIMALWFGTLAVTGAVSAFSMPQIVEAINPLHGIAFFRDNGLAGYFVLSEVILCATGGEALYADMGHLGKRPIVRAWHFVFVALYLNYLGQGVFAIAHPDAKNLLFGMVRSQAPALYIPFLILTIMATIIASQAIISGVFSIVYQGITTRLLPLMRVDYTSRQIKSQIYLGAVNWSLMVAVIFIMLVFRKSENLAAAYGMAVTGSMTITGIMMIIVFSHTTKKWRALVALVVTLIAAAYHVSTFSKLPHGAYWSIILASIPFVTIIIWTRGQRTLYRALKPLDLETFLISYEQIYAKGPIRGTGLFFTRETDVVPPYVVHCIIRSNIIYERNVFISLMISDEPLGVETELIRGIGPGLDAFRIEAGYMEMVDIERLLKENGIQEKVIFYGVEDISTRNPFWRFFSVLKKLTPNFVQFHKLPASRLQGVVTRVEM
The following text describes a protein:
Function:
Seems to act as a scaffold protein in multiple signaling pathways. Modulates excitatory synaptic transmission and dendritic spine morphology. Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction. Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AMPA-type and NMDA-type glutamate receptors. Plays a role in regulation of G-protein coupled receptor signaling, including dopamine D2 receptors and alpha-adrenergic receptors. May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton. Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling. May confer to Rac signaling specificity by binding to both, RacGEFs and Rac effector proteins. Probably regulates p70 S6 kinase activity by forming a complex with TIAM1. Required for hepatocyte growth factor (HGF)-induced cell migration (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Nucleus. Postsynaptic density. Cell junction, adherens junction. Cell projection, dendritic spine. Cytoplasm. Cell membrane. Cell projection, lamellipodium. Cell projection, filopodium. Cell projection, ruffle membrane. Note=Enriched at synapse and cadherin-based cell-cell adhesion sites. In neurons, both cytosolic and membrane-associated, and highly enriched in the postsynaptic density apposed to exitatory synapses. Colocalizes with PPP1R2 at actin-rich adherens junctions in epithelial cells and in dendritic spines. Accumulates in the lamellipodium, filopodium and ruffle membrane in response to hepatocyte growth factor (HGF) treatment (By similarity).
Domain:
The PP1 binding region is natively unstructured, upon PP1 binding, it acquires structure, blocks a substrate-binding site, and restricts PP1 phosphatase specificity to a subset of substrates.
Sequence:
MMKTEPRGPGGPLRSASPHRSAYEAGIQALKPPDAPGPDEAPKAAHHKKYGSNVHRIKSMFLQMGTTTGPPGEAGGASGMAEAPRASDRGVRLSLPRASSLNENVDHSALLKLGTSVSERVSRFDSKPAPSAQPAPPPHPPSRLQETRKLFERSVPAASGGDKEAVARRLLRQERASLQDRKLDVVVRFNGSTEALDKLDADAVSPTVSQLSAVFEKADSRTGLHRAPGPPRAAGAPQVNSKLVTKRSRVFQPPPPPPAPSGDAATEKDRGPGGQQPPQHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTTATTASPAPEEPKAEAVPEEEASSSVATLERGVDNGRAPDMAPEEVDESKKEDFSEADLVDVSAYSGLGEDSGGSALEEDDEEDEEDGEPPYEPESGCVEIPGLSEEEDPAPSRKIHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQSEVAQLIQQTLEQERWQREMMEQRYAQYGEDDEETGEYATDEDEELSPTFPGGEMAIEVFELAENEDALSPVEMEPEKLVHKFKELQIKHAVTEAEIQQLKRKLQSLEQEKGRWRVEKAQLEQSVEENKERMEKLEGYWGEAQSLCQAVDEHLRETQAQYQALERKYSKAKRLIKDYQQKEIEFLKKETAQRRVLEESELARKEEMDKLLDKISELEGNLQTLRNSNST
The following text describes a protein:
Function:
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MSRLLACLKQLQARSLIHNTTLLQPSCNVNSVYLGADPTAASLHVGNLVALMPLVHFFLNGFPVFTVIGDATAQLGDPSGRSTSRKQMAETTRTANSNSIHNQLKDLSSSILSYAQDCNYPFSQMPSSSQWSIVRNSSWYENLKLLKFLSSVGPHVRVSQMLARDSVTTRLQSPSGLSFAELTYQLLQAYDYSYLYENHSVNLQIGGSDQWGNITAGTDLVRRTHPNANVYALTTPLLTSSSGQKLGKSAGNAIWLDPKLTDSYSLYQYFISAPDDLACKCLDMLTLLPLEQLEQIKAEHEKDPSQRIVHKYLASNVVRMVHGKKALELAQIQTKLLHGAHQAPFGFYSEAPQQGDSFPSLPEIRALFKDCKFYRTIDSSIKDQPFSRLLRTLQIYTSRKEATEHILSGAVSLGHKPILDSNYKFPDNSLFVLRAGKRTFVLDSL
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MAETEENRGKRSLSMQMNGFSRDLLHKFMNGNNFKGKLQQIPPNENHEDEDDIELSLGLSLNGRFGVDPERAKRLKRSSSINNVVFINGEDSNNSRGFPFGSYATLARTCSLPVETEEECRKRKEIQSLRRLEAKRKRWEKLQNVRVVKDSVDLEENREENGNGYSNGQGSVGNIIYVNNENSLPLSQGSMGSQGSGSSGISDLGSQPIQGPSDCTGTNIPASIKSAEQEHEQEPVAAQPETTSEKAPSICNGNASKETKEMIKNFMLNMPCVSTKGDGPNGKKIEGFLYRYKKGEEVRIVCVCHGNFLSPAEFVKHAGGSDVANPLRHIVVNPAPLMG
The following text describes a protein:
Function:
Component of the intraflagellar transport complex B (IFT-B) involved in flagellar assembly (Probable).
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, flagellum basal body. Note=Localizes to the cytoplasmic and membrane-bound portions of each of the eight axonemes, localizing particularly at the flagellar pores and at the distal flagellar tips. Localizes to the basal bodies.
Sequence:
MTQNWRPQSRLQTMTFAGTARPMTSMTAAGFTKNPLATAGVASIFDKLPPEPPKDSPEQKADQMEINIFKLLRDGMSAASCKDYVTALGRIREAIKLEQKVSQHRTMNGLADSINLDLRTCIWMHWAQIQALGGQPEMALSTYEKIVKTAEGATLAQIRFNMGNINHNLGKYNEALKNFRMAIDQASPSLPRFRQKIASHMAQSCIKLHRWQDAVDRIEEYLIKQYTLASSVGTDVERQNFYAMTTRFDPLYTVLIGYYALGVPEKMIDAYSRLIDSSILISDHPDSLEIDDHHNGISSKQIAMADAELCNMSNDDELDDLSRYNATLRHEHTNKLLISARLLAPAIAWEESQGYAKLSDILREKGHHGISLQVQMSMALTLLKRNEFEKATDIMLRIDREGLESALALGINVPLSILQKTRNLSLTAAATAVTNQESDLHLLGIDPSVLANQQSVVDRDAVASRGAPEVDMLKTDDDNGTKKQPYAAFVPRGVHTNIAFIYYLKGDYEASARHAQIALEIDPYDSFAHINLGCTYSKTNQWELSLREFLKAQEINMESVQATYNAGLVYFKQQEYKTAYSCFQKVASKLPSYGDAIYMSADCLARMSQIDEAIQMLSNLVTMFSAVKAYDPSIYIRLGELYSIAGDEGQAAHYFKEAHRLVPFSLAVINWLGSHYIKNELYEQARVCFEKASRVDTTTPKWSLAVAACLRKSKQYRDAIYEYKHILKRFPTNTTAMTHLISSLNNIGQHKEADEWAEKLTKLTNNKVPEVTEDRELDEFVKQERRNSVAAVGPGSRAGQDRFEASNNRVSSNTGDLFGDVDIAEELLTEN
The following text describes a protein:
Function:
Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity). Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity). Also degrades other unstructured peptides (By similarity). May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
Subcellular Localization:
Mitochondrion intermembrane space. Mitochondrion matrix.
Sequence:
MLRSFSGAGKCKCRIPVSRQPVCGRSLRISSTLTPWNQSRRAASTVTSLDSFPNVGEKLHGFTVQEKKHVPELHLTAVRLKHDKTDADYLHVAREDKNNVFGIGFKTNPPDATGVPHILEHTTLCGSEKYPIRDPFFKMLPRSLSNFMNAFTSADHTTYPFATTNRQDFQNLLSVYLDATLHPLLKEEDFRQEGWRLGPEDPRSILTQGEQSKGNLQSEDVVFKGVVYNEMKGQISDANYLYYIKYRESICPSLNNSGGDPQYITDLTHQQLVDFSKRNYHPSNAKILTYGDMPLSVHLKQIGEVLDGFEKGQADTDVKLPLDLSRGPLNVTVPGPIDTFASEDKQYKTSTSWYMGDTTDVVETFSVGILSSLLLDGYGSPMYRALIEGGLGSSFTPNTGLDSSGRVPIFSVGLTGVSEADAPKVKSTIKRVFEESLSSGFNDEKVQGFLHQLELALRHKTANFGIGVMEKTLSSWFNGSNPMKELSWNEVIDEFKKKYEQGGYLESLMQKYLMNDNCLTFTMVGTPSYNKDLDDQEMVRKEKKLSELVERHGSVEQAVSALAEEELQLLKIQEEAQNADLSCLPSLRVEDISREKERKPVRESKMDDIDVVWREAPTNGLTYFQALNSFEELPDDLRLLLPLFNDCIMRLGTGDKTMEQWEDLIKLKTGGITTSTLHTSSPTELGKFREGLQFSGYALDNNIPDMLQILTTLVTETDFTSPHAPAMIQELLRMTTNGALDAVAGSGHRYALNAAAAGLSRSFWVQEQQSGLAQLQATANLLRDAESSPERLAELIDKLRLIQSFAISKGSGLRVRMVCEPSSASQNEIVLQKWLAGLPRNRSPTSPLDHTSVNSVANRVFYDLPYKVYYSGLAMQTVPFIDPSSAPLSVLSQLLTHKYLHPEIREKGGAYGAGASNGPIKGFFAFTSYRDPNPVNSLKVFQNSGIFARDRAWSDRELAEAKLGIFQGLDAPMSVDEEGARYFMSGVTHEMDQRWREQVLDVTAKDVNEVAQKFLVEGSRQSICLLGEKKDWADSDDWEVRKLSMNASGEPVIDPLSQDGAVASA
The following text describes a protein:
Function:
Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.
Sequence:
MEEQYAALASKITSLATSHQKPRYLVAVAGAPGSGKTTLATAVAAQINRSGLLSHKSTNQSDDNSQTNEIAKRALVLSMDGFHLPRSELDTLPNKERTEAYVRRGAPWTFDIPAFLEFMRTLRLWADSGSPSSSSEETAGVLYAPTFSHSTKDPIPNSIVIDHTTSIVIIEGNYLLLDKPQWRDIAPLVDYRVFVDVDLAEARERLAQRHVEAGIEQTLEEGFLRVDRNDAINGALVKGHVVDGVDIVLRKKETNPSFVLRAVKDVAFEDRVIPPLKDPWDVRVQVAQTGICGSDVHYWQRGRIGDFILESPIVLGHESSGIVTEIGSAVKNLKVGQKVAIEPGVPCRHCDYCRSGSYNLCPDTVFAATPPHDGTLQKYYITQADYCYPLPYHMGLEEGAMVEPVAVAVQITKVGNVRPNQTVVVFGCGPIGLLCQAVSKAYACKKVIGVDISQSRLDFAQAFGADGVFLPPPRPEGVEETAWSEKVAALIKEKFGLGEGPDVVLEATGAQSCIQTGVHLVKKGGTYVQAGMGKENVVFPITTACIRDLTIRGSIRYSTGCYPVAVDLIASGKIDVRAGGGGL
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Sequence:
MNNTIYILGAGSIGSLLAYELASLKSINNRVILLLRDKSRVNSFKDKNSTLKIDRLFEENVPHLCCQVTASEPSQLNVQSIENMIVTTKAGQTENALSKYLPYLSKNSNILFVQNGMGAVENVCGKLWPEEQNKPSIYQGVISHGCFQTAPFHFSHAGLGDLKISKVPKNPKKILPDEAAETPCEMIKSLGKSELLRLRYMNYPELLVNQCEKLVINACINPTTATLDCVNGELYNDESAKELFRCIIKECVDIFFKCIPLFKNNEEAEKILNVNRLLDRVMFVGTKVNGANSSSTRQDCLLLRETEIDAINGYVVKLAENNGFQATVNKTMMLLTKSRLGLNRCRAHAR
The following text describes a protein:
Function:
Seems to have a peripheral vasodepressor effect and a central vasopressor effect.
Subcellular Localization:
Secreted.
Sequence:
MTAHILLLWLFASSILGDPDSAGRLTRHQVSLKSGRLCSLGTCQTHRLPEIIYWLRSASTKELSGKAGRKPQDPYSYGRRRRRRRRRREARLLRRLQDPSLRRAQLAG
The following text describes a protein:
Function:
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSTSEGNAANRFAGRVKQAEDPFVKALRIKVNGLKRNMKDLEFAKKEVVCETARLESIRDTNPDRVKQQENVIAEAQMMIPHSENRVRAAIKDLQDFLDTHENDAEEGELMQDARTTLESAQLTLSKQ
The following text describes a protein:
Function:
Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Sequence:
MQMSEPLSQKNALYTAMNRFLGAVNNMDQTVMVPSLLRDVPLDQEKEQQKLTNDPGSYLREAEADMYSYYSQLKSIRNNIEWGVIRSEDQRRKKDTSASEPVRTEEESDMDLEQLLQFHLKGLHGVLSQLTSQANNLTNRYKQEIGISGWGQ
The following text describes a protein:
Function:
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
Sequence:
MTEQNAESIASHPDGNALHLTPDPQLLAGAQAAFKQAYAPYSKFRVGAALRTPDGQVFFGANVENSSFGLTRCAEQSAVQALATAGGRTFTDLVVYTEASPPATPCGACRQILFEFAPDARVVCTNAQGEVISGLVRDFLPHGFRLAQEEEEPGAGG
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MSKSRRDVNKVQIGYHRAENTETVSSPHTYAYSSGKSAPSTTKPDRPTVSNIRIASAVAGLPPSRFAANASVKREKNDEESESPTAAASSVSSSLLHGAASEARTTVDGFPWSTRRVERMSFEMQNVSPPIANLLRRVLTTEVPTLAFDRVLIEENDSPVLDELLSHRLGLVPVAGPVMKMHYITESNQASFSNLDPSRVLLFELDATGAKDAAVTPVYSGQLQWVPLPGQDKTAGAVAVACQAGREECAGAAGATDHSADEDDDAVFLVHPDILLTKLGPGQRIKLKAIAVKGFGAVHAKWSPVSACYYEMKTSVELCERLTGSAAEALIKSCPAGVFGYEGGQRGAAATVVAPEKCTLCRECLRSEDKGAEAAANKGDRVRVQKDKTHVLFHIESVGQLHPAQILRFGLRLFAERCRALAEMVQSTEVHVVDASAKSLEL
The following text describes a protein:
Function:
Transamidinase that catalyzes the transfer of the amidino group of L-arginine onto the amino moiety of acceptor metabolites such as glycine, beta-alanine, gamma-aminobutyric acid (GABA) and taurine yielding the corresponding guanidine derivatives. Catalyzes the rate-limiting step of creatine biosynthesis, namely the transfer of the amidino group from L-arginine to glycine to generate guanidinoacetate, which is then methylated by GAMT to form creatine. Provides creatine as a source for ATP generation in tissues with high energy demands, in particular skeletal muscle, heart and brain.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
RLREAKGPAQSHAADKSRSGDRRPREVKARAHGRPADGRRRGDEKGQGGEGTGPTSAGGWVAERGREGGPSGVGGGRGPLTGVGDEEFGSAGLEAVDEGPSAAVVVEAGQGAAQLGHGQPQPDVGRPVAEQQGGGAAPAEAQAEAQGAGGAVAQGLGLAEGQRVLARPHEGPARLPRRPVPQGVQHGADRPPPPVAPQPPPGPHHPRQEDQVSGQPAHRAPPRPRPAQAQHQRRPHQRRQHQRPHQRPRGQGQHPAPRASHLPPGRDAPPEGGRPERGGPARGGGKEGGQRGGPGREGGRAEGWSWERRRASGGMVPGEKEGERRGGPGREGGRAEGWSWERRRASGGVVPGEKEGERSGGPGREGGRPEGWSRERRRASGGVVLGEKEGERRGGPGREGGRPRGGPGREGGRAERWSWERRRETGGMVLGEGTGDQSGGPGREGGHYIASRLGRAFTGRVQRTFQSTQAAAATPDPCAAADKAPDPVPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKESISGTLTLVKTPDSSKTAVCPAPDLPLCSLRVQEI
The following text describes a protein:
Function:
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Sequence:
MSENNKPRYPLQQILVEDLFSSNKLVVLLLIGILVSAMGTIWITHKTRQLISENGMLILQRQALENEYRNLQVQEATEGDSTRVESIAISTLKMKVVSSEQEVEIRE
The following text describes a protein:
Function:
Catalyzes the conversion of cytidine diphosphate diacylglycerol (CDP-DG) and glycerol 3-phosphate into phosphatidylglycerol. Essential for the synthesis of anionic phospholipids, thereby playing a role in balancing the ratio of zwitterionic and anionic phospholipids, which is thought to be important for normal membrane function.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVAAVLTLWSMLQYLSAARADLLDQ
The following text describes a protein:
Function:
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
Subcellular Localization:
Nucleus. Chromosome. Note=Loaded onto the nucleosomes of condensing spermatids.
Sequence:
MSTSRKLKSQGTRRGKNRTPHKGVKRGCSKRKYRKSSLKSRKRCDDANRNFRSHL
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MQAGGGGDAGDTRGRHRIQAELKKLEQEARFLEEELEELDKTDKVSAALQELMVTAESKADPLLPVTTGPACQSWDRWFEGPQDLRRCKCWFL