The following text describes a protein:
Function:
Catalyzes the synthesis of the second messenger cGMP from GTP. Regulates cGMP production in gametocytes; however, is dispensable for the initiation of gametogenesis. Does not have adenylate cyclase activity.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Domain:
The N-terminus contains a P-type ATPase-like domain which is required for guanylate cyclase activity.
Sequence:
MKTQTLSLMNINGKRKFLGTNNKIYRKVIINPTSEDDIQKFCRNYFRIYNFSLYNFIRRLISFDAILVYSLFLTVYIFSEINHGETKKYLFIDTAISLFFNIILLIVIESLFELKKLKDVKNANSQYYLRIVPKMSYFEKVMTKDIKVGNIIRIFQGDEFPADVVILYVKNNANAIVDSFKIDGLFRKSIKYAVDKYKIDKDYLKMLSEINGVIRCELPNKNIFCFQGNFKLDKHPRSLLLNYENFALQSSVLKGAEYIDAVVVYTGADTKKNLNIPQKIEENKTFCIKMNNIVYYLIFMYFVFVVLSIVIKTIFFHKKNSFQNSRDSFLSMLEDFVGLYILVLPIMMYSEKSLIYIIQSLRIENDLRMRNTDSEKPKVFNKNKNDSLGNVDLLATSRNGVLVKRKELLVSCVINNVMYGKKDIICSRTNFKLPTLNILDSERKNVSNLLNLDERIFKDPENIFFPTRDFYSFLKLFENKISSIYNPYSSSLSNLLKEKYKNYVNEEILNKNVKLTSFVKSQLTIGYNQICEDDELSYNCYEIKEDSQKENIQSVKIEDFILGLCGCNRIIIYNEKSLDISMNEYKSDNFMETYSKFETENEEYHENDHDEYHNMEHSDDENINSIEYEDICLYNIIRNTGFSIYCYKNTLFLYNLMKECKVYFLTCYHDFLRSNKFSMCILKCGYSINNEKEGGILYVRGYDFNILPYISKEKNNIKKIKNVIKIYTLNYLKVIILCKKQISNEDIAKYIILKSISKKLSFKFYDLIKLFFLYDLEVIGIIGLKNQLREGVKETFNDVINFDIKSWIFANECSKDTYLTALQCNLIVSSSNLFLINYYNLKNTHEEGANILFHNFISSLYKLKSNSYAVVINDESIKNIMTNVESMKIFLCIAMRATVVLFCKLQNETKGKIIRTLYALTSPKLTVLGIGTTLNDAYLLKYSSISVFLSLNEHVNILYNISDYVLQEFKFISELLILGRLNRFSLCKVFLWIIYLKITVVSFYFFHNFDNYFSGSSASSILYTQTTFALLHYFLIIAFSAYEIDLPYKFVRRLPYIYQLSRRKYFLNNNIILLTIIEAILISLTSYYILRLNVFHLITHREFTFHIFILNVFITTEKILLLSKTWHIYFFIMAVLIIGILLIYVNIFTLVDCIKNGKCEFSLFQMENIYFWTSLFPILYINFIFDKLMKYIKNRIYPDISDYLRKYFLRRICCHNNDKFLSQRKIKGINKFVNFEKNDILLKYIPTPKIYKIKDDPTYYNKSKRSKFLYDTFRKVIDINVKYRNQQLNLEYKTYEKGNKLKLRIIVILLFLIYIIIFSSQTIIDINTKSNIHYITMFYIIYFVLACVLLIYIRIRNKATSTFFFFLSRFLLICGFCIELYDNISNDILNVLITYSFTVSYIFFMSFKILEALLVCISILLLTFGVYYEKNKNMIDICTHFCSNPYLSINNLDHMNISCLCKKQIVIFLISLLSFTLICLSMKYYEIFYLKKKFLFRYKQKVNLAKQIEILHTMLPNFLVEYLLISDPKNDGIMVGKNISGEDRGIISVIFCDIDDFQNMVSTLQPHVLVETLDNLYLYFDKCIKYFNCIKIETVFESYLAASGLSEKKNNALDKIMYDTKCAIKLAIAQLSAKYYISYKVLDTREHFSDNSTSYDKYINKNISLKIGIHTGKAISGVIGSVKPQYALFGDTVNTASRMKSTSLPDHIHVSYDTYKYLKEDNTFIWKERKVFIKGKGKMKTYLLVDILDDVKRKGESLNYYSSSNLLLSQLGSEAVSIYEEREDIKEGSMDIIKESSRDIIKEDSRDIIKEISTNISKSSSRNISKSSSRSISDIKEGQIIDKEDLIFKINRMKNKIDSRYSKRIDKESRDKISDKTNHVLDEVVKHSDIHLLNYEINNKRCKKMKGDTNNENKLIGDIFNMYDKKIKYIYKKNYKSKSMENISFIKHYRNTKYKKSDYLLLDNKGESKKFKRNTSYVLESPLHLIGDIVDNNIKRKKKKKEIKTIVSDDMFTSPVNIKEYNYNEQERKKEIVGNLSYDKTKKIFPFIKFTKEGRIKKKKIEKKEKKEKKENNNNFLYNDDYSSYSSPKYGDNENNFVIKYIRERKDFQKKFDHPNFNFSKFLHNYNPMKNKNKNKKNNKNVRRNEYPNYTSSSKDGVSYNFLSDSLFSSDNEYSSDNEYSSDSEKYYKKRFKKNKKIIKFDDLFTKIYIKKKRLLQMNNYDVKGKGKKLKNKGMERNKTKYKNVNEITKMKYFVNNENRDHEVNKEDISKSMQKYFLHISKHKKEQIEDKKKTHKYFHKNVECVYPYAGNNINHNFSRNEKRKYSINLYDHLDEQEKIKGKKKYFNKDKELIGSINKQTERKPKKKNKKNIENKKDKKKIRMITNKTKEKHSNSIISVEEQNMNHNNSLKKKEVNFTGKNEEYLNRANTNCSLGIKEMEEDVYEFHSNNIYYNNQTSYSDDINNTTKLKGMGNNTNDISKNKGKNKLGKKISFFSMNNKYHESEIMNEEDNKNMLNLTQSQIINKDKYNYFTHCPSLKKKKSVFTKINNLFKNYFKSIDVHEKFGFSKKFKFHSKDSDDIKGNNNKISKNRYNNNNNNNNSNYSNIDSGKYSHNNKKNHHHNNNKYHHHNNNKYHHHNNNKYHHQNNNYEKHHHSNNSRVMLSKGEKTEKNENVDYAYQFDNYDKKLLKKLTSNLQLNKKNVKNFNMFYYKFNDEELEEEYTRNYYREIINIDLTKKLIIIFIFTEIFLSLCNIIELSFYEKKLRYNDSIVIIWLIRSIYLFIITYIWIILKTKLKEYKNNSSKMMWTIFILNIFLCSWGIILIDLSCIHYSMLLGNKNERALFFMKDASELIICIQLIFIKNMLFKHKFFFFVFFYIFLIYSFSKLFSIHTCQTHICCSIILFISINILYFWYSEYLDRIQFLVKRKRNRMEKISQDFLTKILPRQVLEEYQNDNLQLTYKHEKIAFLFADIVGFTKWSKTVSPKEVLKLLQKLISKIDKDTIKLGLYKLFTIGDAYVATSQPNSSITDESEALEGILNILKLAKLILHNINTIKIQFNKHDFNMRIGLHYGSCVGGIIGSVRIRYDMWGLDVLIANKIESNGIPGEIICSEQFRHFFIQNEPQAKLNFWYYKSISINDQDIKLYVIEDKNYEEDYDPKVIDYTTLLKLRQKKGLRS