lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MGIPAFFRWLIDKYGGLIQETTEPREADGGRSVVDFTTPNPNGEYDNLYLDMNGIIHPCAHPEKGPKPKSIEDMIQSIYEYLDLLFAIIRPRKLIYMAVDGVAPRAKMNQQRTRRFRAALDSRLDKDKEAALWRERIYDGLATQQEYEQYMEEKKNKFKFDSNCITPGTLFMDRVAESLRTYVAEKLTTDPAWKDVKIIISDASVPGEGEHKIMDYVRHQRAQPDYDPNLKHIIYGLDADLIMLGLATHEVNFDILREFIQPIARGVCHKCHKKGHLAIECKEEVDDSVKDFLVKNYQILHLHLLKEYLELETKVSTPFGFDIDRIVDDFIFLCFFVGNDFLPHLPNLEIKDGAIDRVIKCYKELLPSFDDYLVSNGEVNFPRLSQIFVALTKGEEESFQRKIQKDAQILKKRQNLSNIVSRPNSLNLNDKTSLSHKEAADKFLAEILKPVEETTQDEEKEEDSRPTKKSKNSSASSTTTTTVKSNKKAAELIKNKLIGGGGGKEKDKEETEQDDEQSASSKKSKKRGLKVIELDDDQQQQLNIVAAENEKKLLNKKSKQQKAAQIQEEADEKEHQENDKPSLFVNSYDDSSLPTEKEIFFDNSRNIKYSEEGWRDRYYQSCFQVENEDDIKQICKSYVEGLVWVLKYYFKGCSSWGWYYPYHYSPYITDISKFFDQFEYPQYEMGEPFKPFNQLMSVLPPASCQFVPKPYQKLMGISVDGEPVEESPIIEFYPRAFRIDRGPTEPLYKGVCLLPFINSIKLLKTISKTEPLLTEEEVDRNTLGHDLMFCHKDSNINSAFKEGSVTQLPENSSKIYGTIEDVSALAKKKMPPLMDAVAFKYNNSSVPNGYSFNYSTLKGSIIPKKSITLFKPRTQNAAINRMVNNSLGGSNQYKDNQQFNGGFGNVGSGGYNNKQIGYNRFNNQNYNNNRYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNYNNYNNNNNYKNNNYNNNGNYNGNNSNNYNNNNNYNNSNYNNYNNSYNNGNNYNNNNNNGNGYNSNYNNNYNNNYNNGNNNGNNYNNNYNNNYNNGNNNGFNNNNNNNYNNNNYGGYDNNNGFNNNNNNNNNNNNNNSYNYDFNNLNDPSLIDINNYGGGGNNTDLGTLVASNNNNNNINRNQQQQQPQQQQQQQQKNKFNNNSNTKNQPPAKVPMKYNPFAKSKK
The following text describes a protein:
Function:
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
Miscellaneous:
MISCELLANEOUS: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
Subcellular Localization:
Cytoplasm.
Sequence:
MSNVDNRYIEEELKESYLDYSMSVIVSRALPDVRDGLKPVHRRILFAMNEMGMTNDKPFKKSARIVGEVLGKYHPHGDSAVYGTMVRMAQDFNYRYLLVEGHGNFGSIDGDSAAAMRYTEARMEKITAELLEDIDKDTIDWRKNFDDSLDEPTVLPAKLPNLLLNGAIGIAVGMATNIPPHNLGELVDGILAIIDNKDIEILELMNYIKGPDFPTGAIIDGRVGIIDAYKTGRGKIKVRGKVDIEELKNGKSNIIVSEIPYQLNKANLIEKIANLVKEKKITEISDLRDESNREGIRILIEVKKGEEPELVLNKLYKYTDLQTTFGVIMLSLVNNVPRVLNLKEMLNEYIKHRFDVITRRTAFDLDKAEKRAHILKGYQIALENIDRIIELIRASSDGTVAREQLIEKYAFTDIQARSILDMKLQRLTGLEREKIDTEFKEIETLIKELREVLEDNNKIYDIMKKELLELKEKYGDKRRTKIEEERMEILPEDLIKDEEIIITYTNKGYVKRIEASKYKAQRRGGKGVSALNTIEDDYAEKITSASTLDTIMVFTDRGKVYNIRAYEIPDLSRQSRGRLLSNIINLSEGEKVRDTIVIKEFSPEKEVVFITKKGLIKKTSLGEFKNINNSGLIAIKTREDDDLIFVGLIEDVNKEEILIATHDGYCTRFLTDTIRATGRSTQGVKAITLREGDAVVSAMLIKNPETDILTITENGYGKRTSLDEYPQYNRGGKGVINLKASEKTGKVVSVLEVTEDEELMCITSNGIVIRTSISEISRIGRATQGVRIMKVADDEKVAAITKIKKEEELED
The following text describes a protein:
Function:
Central component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM20 and TOM70 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Docks TOM20 and TOM70 for interaction with the general TOM40 import pore (GIP) complex. May regulate the TOM machinery organization, stability and channel gating.
Miscellaneous:
MISCELLANEOUS: Present with 6610 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass type II membrane protein.
Domain:
Its cytoplasmic domain associates with the cytoplasmic domains of TOM20 and TOM70. Its intermembrane space domain provides a trans binding site for presequences and the single membrane anchor is required for a stable interaction between the GIP complex proteins.
Sequence:
MVELTEIKDDVVQLDEPQFSRNQAIVEEKASATNNDVVDDEDDSDSDFEDEFDENETLLDRIVALKDIVPPGKRQTISNFFGFTSSFVRNAFTKSGNLAWTLTTTALLLGVPLSLSILAEQQLIEMEKTFDLQSDANNILAQGEKDAAATAN
The following text describes a protein:
Function:
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Subcellular Localization:
Secreted.
Sequence:
MFIRSIIVGTLLVCSLWIETTVAGSSFLSPEQPKMQQRKVSQKSVTKFHRRDAEVALDVHGNEVKENRNEMEIKFTVPFEIGMKISEAQYKDCEQMLEKILEDILNTNLKDYKH
The following text describes a protein:
Function:
Epoxide hydrolase involved in the biosynthesis of cucurbitacin and mogroside tetracyclic triterpene natural products (e.g. siamenoside I and mogrosides IV, V and VI). Cucurbitacins have cytotoxic properties and exhibit deterrent taste as a defense barrier against herbivores. Mogrosides are nonsugar highly oxygenated compounds used as high-intensity zero-calorie sweeteners; they also possess pharmacological properties such as regulating immunity, lowering blood sugar and lipid levels, protecting the liver, and acting as antioxidants and antitumor agents. Catalyzes the hydrolysis of aromatic epoxide-containing substrates, such as the conversion of 24,25-epoxycucurbitadienol to 24,25-dihydroxycucurbitadienol.
Sequence:
MAAEATGEVRQWTADINGISLHVAESGPSTGPAVLLVHGFPEMWLSWRHQMAALAARGFRALAPDLRGYGDSSVPADPAAYSIFHIVGDLVALLDHLRLQKVFVVGHDWGAQVAWHLCLFRPDRVRAAVILGIPYFPRGPRPMTESFAKLGDSFYINQFQEPGRAERAFGRYDVATVLKKFYALEIDELIAPPGVEIIDFLQAPSSPLPWMTDEELGQYAEKFQKNGFTGPLNYYRMLETNWRLTAPWSGAKIIVPAKFILGENDVGLQSFGTEKYVKSGGLKSNVPNLEVSIIEGHHFLQQEKAERVNSEILAFLDKFANEEASA
The following text describes a protein:
Function:
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling.
Subcellular Localization:
Virion. Host cytoplasm.
Sequence:
MWDSSYMQQVSEGLMTGKVPIDQVFGANPLEKLYKRRKPKGTVGLQCSPCLMSKATSTDDIIWDQLIVKRTLADLLIPINRQISDIQSTLSEVTTRVHEIERQLHEITPVLKMGRTLEAISKGMSEMLAKYDHLVISTGRTTAPAAAFDAYLNEHGVPPPQPAIFKDLGVAQQACSKGTMVKNATTDAADKMSKVLELSEETFSKPNLSAKDLALLLFTHLPGNNTPFHILAQVLSKIAYKSGKSGAFLDAFHQILSEGENAQAALTRLSRTFDAFLGVVPPVIRVKNFQTVPRPSQKSLRAVPPNPTIDKGWVCVYSSEQGETRALKI
The following text describes a protein:
Function:
Peptidoglycan hydrolase (autolysin) specifically acting on polyglycine interpeptide bridges of the cell wall peptidoglycan.
Subcellular Localization:
Secreted.
Sequence:
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPATAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGNGKVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MFDLNASDEELKSKYGLRNMHPTDIGDVTYFDTPIPEDLSDLTPQQQYELLIKLVDLNQPSPSQAGDANILLDLIIKQDTSKSQAIRDSKKSLSQFEHQVHKYNEDLKKIIESNSIHFINTKWKIDNAMIDFMKSKTKAQQDRASSRVFNPQRRNLTNKEGLTAELEDNINSLQANTSSMIQPIIESKAKEDKVVKMIEFTKANQNFFDLPNSLVHSLSLNNNEKFIDDYNRYIHDKDRFLSVLNNRYRDQVLKLTHDNINGKNDQALRTIEDDRKLQLTLISKVFKEIDTIAHNYRNKIYQEFLSLDHEASKTQSTSKFMSLVDNLSRLNLDDKMKNPIADFLTKQIEAIDKDFEYQVEKFDSKFLLMQNKLIDYIGSLNPERREGSHINYINEKYDTYKDEINSATINGENKLMIIKEAFESNDSLDLSLINEAWLVLFNFINYLDNMVLSNLLKFLNNYVHYIKLGIDSQGKIRDSAIELINKVVVIMMALFDDENNNNNNNNNNKEKNNSNPLESSPKNYKQFVPYYTNSLSTIYHLTKINRIVNKIINNFGNFVGTIGNISQYSETNKVMKSLKNSSTKINQKILEAICATWVNDCSQFYELEDWTLDKQNNKHNNNNNKNKNNNNNSGNAKCTKLMNVIQCYQLYVLLKISNLVIHDQSSDYNVVAVYPSKRMLVSIEIQFMRSLNIIVDSMMKKYNLDRQISQQSSNNMDDSNAKNLQVFKILTMNNFDKLSRIIYPELLLQFDKFFDKDLSKQNLKLFADIDKASLTIIDDILNIEKLYIAQTVNKFFHTTTGAKAKAKAKAKGTNISYTSPQVLKVDGFVYEILIHFVKLINKIKPLTNEEVFVTIINELQLNLLKNILDNTRQILLKSSLAYVNLKLDANFILLVFEKSKLLQLNDSSYKILQILLNEIDNKNNELFNDKNQQFNYSKKDFDEILQLNMQDSANEFSCF
The following text describes a protein:
Function:
Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
Subcellular Localization:
Cell junction, gap junction. Cytoplasm, cytoskeleton, spindle.
Sequence:
MGNQAGRVEELEQGVPSAKKSGIPAPREIPTTISRDRLSLRDQLRTASTKKVVPSASTSSLSALAKHSRPPVKAKSDGETNDKAILECQVKELLAEAKAKEFEISKLRTELKRCRDRGMLDVVTPEGTDLDLESLVAQPAEIQSLVKTMREKNRTFQRELAALREENQTLKEKCFIMEHSSLSSSNNSNASPPTSLASPAKNPVNGIVLDTSRTPINGSTLKNSSSSSSDITKGSPSPDSSEFEKIPSRSDSIGNSTGKSKGSTGPNSPQARDLSVECLTEQIQKMEESHHSTAEELQATLQELADQHQVVQELTAENERLAEEKGLLQTSLQQQRERVENLVQKNESLLARLQEQSKSEESEARAARISELEQRYAELVESSRFEREKLVDIQQQLTSSLRSLEKEHQEAQGLIRTLKEEKDLLQNRIEKEQEVGSKITRTLEECNSSMEALKVENGRLKVQMDIERQKVAELKAMQSASDNTELQHLLKAAHSEKERLELSCTELKQELLKANSEIDRVKGMLSKAEAECQRLQELCASQEKEVSSSAQRLEERAAEKDTQIKDLKETIFELEDQVEQHRAVKLHNNQTILDLENQVKKLEEQKSDLEKQIKALNKQMKDDAEEWRRFQADLQTAVVVANDIKVEAQQELRGLRRRLQEEQERSAKLAGEVEQLQGSRLKNEEAYSSDTDTSPHWCGISVSQIPTASSESGTTVKSLIKSFDSALQGKMPFILPASLFPSDLAVCPVRIFPKNSYAVSIYRCITQKLARTLKKNDKHLLILQKKCLLPGGTNTNPQETGSETALKLFFFPFPPIKIVWVFIWFSDKLTGSNDEMKPTSLMRKSPSLESVIKTPAALSGRTSSLSYPKANSKLSSQEMCFTAILKLENGGCMCSDLCCISLSSWQNIDVTNFSSSWSDGLAFCALLHTYLPAHIPYQELLSQDKSRNLTLAFQAAESVGIKPSLDINEMMHTDRPDWQSVMQYVAQIYKYFET
The following text describes a protein:
Function:
Cleaves GlcNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrate (in vitro).
Sequence:
MLTGVIEGFYGRDWRRDERATVMDWIAAAGMNTYIYGPKDDVHVRARWRVPYDAAGLARLTELRDAAAARGMVFYVSLAPCLDVTYSDPQDRAALLARVDQLARAGLRNLVLLFDDIPSVLPEADRHRFDSFAEAQADLSNMVLRHLRGAGHVVFCPTEYCGRMAGGDPRGSAYLQRLGSTLDPAIDIFWTGPEIVSEEIVAAHLAAVGEVLRRRPVIWDNFHANDYDIRRVFAGPLGGRSRDILPLVAGWITNPNNEAEANFPAIHTTGAYLADPDYAPERAIAAAVAAWQPRFRLAFGDGAVPSDLVALLCDLFWQPFALGPETTRILSALRAALTVPRPDPSDPAWRAALEDLRDLKRRINKLFTLMTEIENRDLFHTFHNYLWEAQEEVGHLVAYCDWLDEAPPPGAVFPATDRIHNFYRRGFGVAVQDILQRDRQGRYHHGV
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MTEYDDRSCASNMFLPSCTYYVSTPDFTSVSSFLPQTTSCQINFPYSPNIAQVQPVREVGFRDYGLEHPKWRYRSNYASYYSTDEIMHRDLIQSSSGRADVIFKNESLYGHHGGTSSPCNFFTNVGRNGVLPQGFDQFFEATNSDKTGAELAKQKTDSASSSGDAANNSQDLTKIENTEASGSVDEDSSSNCNSSSSTKSRKKRCPYSKYQIRELEREFFFNVYINREKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF
The following text describes a protein:
Function:
Component of the endoplasmic reticulum-associated degradation (ERAD) pathway. Specifically required for the ERAD-L pathway which mediates the degradation of proteins with misfolded lumenal domains within the endoplasmic reticulum (ER). Facilitates retrotranslocation of misfolded proteins from the ER lumen through the ER membrane in conjunction with HRD1. Both proteins have lateral gates facing each other and distort the membrane region between the lateral gates, making it much thinner than a normal phospholipid bilayer. Substrates insert into the membrane as a hairpin loop with one strand interacting with DER1 and the other with HRD1.
Miscellaneous:
MISCELLANEOUS: Present with 238 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDAVILNLLGDIPLVTRLWTIGCLVLSGLTSLRIVDPGKVVYSYDLVFKKGQYGRLLYSIFDYGAFNWISMINIFVSANHLSTLENSFNLRRKFCWIIFLLLVILVKMTSIEQPAASLGVLLHENLVYYELKKNGNQMNVRFFGAIDVSPSIFPIYMNAVMYFVYKRSWLEIAMNFMPGHVIYYMDDIIGKIYGIDLCKSPYDWFRNTETP
The following text describes a protein:
Function:
May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSRIPEGVNKITESAYKNVMEQFNPGLRNLVNLGKTYEKSVAAMTLAGRAYFDAVSRLGEVAIVSPASRELGVVLMEIAEAHLMIHNELDENFKRFHKEVLSELEKKTEADTKYMTATFKRYQTEHKLKQDSLDRSQTELKKLRRKTQSKHSSKYDHKENEYLETISSRQMEMQKFIADGCREALLEEKRRFCFLADKHCVFSYQIGNFHDKAKEVLSENIPRWQEKCTDINKVPEGLATMINGLSVIPEQTPKADHPTRNHVRPMSPPPAPPLKAHVSPLANMFYPQRMSSSDLNSDLGSIGEGSLSRSTSQSSGLSVSQKVRVRTIFPHTAGNSDTLLSFDQGEIISLLMHDEQDGWLYGELERTQHRGWFPSSYCRPYQEQLTSNSNLSTPVRSLSECSLPEEEDDDVYDAVLLPPPDYSDDVPFSPVVPMNPPSNNKVSMTNGTAKVTFLGEGNPFATVKLRPTVTNDRSAPAI
The following text describes a protein:
Function:
Negatively regulates pak1/shk1 kinase activity leading to proper execution of cytoskeletal remodeling and cytokinetic functions; Interacts with pak1/shk1.
Sequence:
MLRFVVGTYTHLIYGVDADIERKKCKPLWLFEAHEGALTALAVDGIYLASTSSDETIKIFDHTRNVQIADVSVPTDIANACIRDMCFTKNHLLACHDNGQISMWSKGSWLLVHTLKSSSHKGITGIAVHPSEKLALTVGGDGKLRLWDLVRGKGGKVLPLSTIPESILFLNESSFVIMSRRGIDAFKLDLTSLFSFSSKSQLNALCLYQSKLIVGRDNGTVLVLDTSDGKILHEFTAHKKRVKSVYPVDDYLITASSDGSVCIWDKDWNLVIEHNIPEGNRITCMVAMLADSNSEPKNVEDEAAKRQSLDSETSETSSESESESEYYSTSKQPPVKRTKHA
The following text describes a protein:
Function:
Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense by signaling through the NFKB and MAPK pathways. Acts synergically with IL22, TNF and IL1B in inducing antibacterial peptides. May have protective function by maintaining epithelial homeostasis after an inflammatory challenge, such as that caused in the intestine by dextran sulfate sodium in a colitis model. May also promote an inflammatory phenotype, such as skin in a psoriasis model. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases, such as autoimmune encephalitis.
Subcellular Localization:
Secreted.
Sequence:
MSLLLLGWLPTGMTHQDPPSWGKPRSHRTLRCYSAEELSHGQAPPHLLTRSARWEQALPVALVASLEATGHRRQHEGPLAGTQCPVLRPEEVLEADTHERSISPWRYRIDTDENRYPQKLAVAECLCRGCINAKTGRETAALNSVQLLQSLLVLRRQPCSRDGTADPTPGSFAFHTEFIRVPVGCTCVLPRSTQ
The following text describes a protein:
Function:
Plays a role in the formation of clathrin-coated invaginations and endocytosis.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle, clathrin-coated vesicle. Note=In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
Domain:
The NPF repeat domain is involved in EPS15 binding; The DPW repeat domain is involved in AP-2 and clathrin binding.
Sequence:
MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTSHSEQEYGKAGGSPASYHGSPEASLCPQHRTGAPLGQSEELQPLSQRHPFLPHLGLASRPNGDWSQPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRRGDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSGPAAQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFGTKPAASIDPWGVPTGATVQSVPKNSDPWAASQQPASSAGKRASDAWGAVSTTKPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAESVTSLPSQNNGTTSPDPFESQPLTVASSKPSSARKTPESFLGPNAALVNLDSLVTRPAPPAQSLNPFLAPGAPATSAPVNPFQVNQPQPLTLNQLRGSPVLGTSTSFGPGPGVESMAVASMTSAAPQPALGATGSSLTPLGPAMMNMVGSVGIPPSAAQATGTTNPFLL
The following text describes a protein:
Function:
Glycosyltransferase involved in the biosynthesis of the core oligosaccharide region of lipooligosaccharide (LOS) (By similarity). Catalyzes the addition of a heptose unit to the heptosyl-Kdo2-lipid A module (By similarity).
Sequence:
MNILIIGPSWVGDMMMSHSLYQQLKIQYPNCNIDVMAPNWCKPLLARMPEVRKAIEMPLGHGAFELGTRYRLGKSLREQYDMAIVLPNSLKSAFIPFFAKIVHRRGWKGESRYILLNDLRANKKDYPMMVQRYVALAFEKDVIPKADDIPVLKPYLTVEPAQQAETLKKFEKQTALLGERPIIGFCPGAEFGPAKRWPHYHYAKLAEMLITQGYAVALFGSAKDEPVGEEIRQALPEELREFCVNLAGKTNLNEAVDLIANCTAVVTNDSGLMHIAAAVNRPLIALYGPTSPQYTPPLSDKATIIRLIEGELIKVRKGDKEGGYHQSLIDITPEMALEKLNELLAK
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSARNIITSLYPCYISQLLIGCAPIKITEIRSNLQIKHRRVYDYSTILILLLIISFIYYRYSLMDFYDFNSSALVKFMTTVYFVIVSGLISTNVIYSRVQRQVMTQFLYKIYTVDKKMRNIGIKLKYENIQYFSTKVLLTGFATFTIYLICLLTTQGFQNRIQGLITYGLLYLAVLHYISSTCSFMTTIQIITNMAENLMKKTEDLLIYKSFYRQIPLREMMKLHQEIYDLLQLSTKIFAAQVLFSFSVAFVIITFQSFSIICAVYNNSPYLRYSIASAIWIVVFVTEKMVLTFSCHKCMFRSIELRQKLGKYAVAHSKNKLLVKEINAFGLQLLHEPLHIYAGSMFLIDLPIFTSVCGTATTYIILLLQTDHKVDLIYSMKKVFGVF
The following text describes a protein:
Function:
Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome. May play a role in ERAD and other enhanced proteolysis. Promotes proteasome dissociation under oxidative stress.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic vesicle. Endoplasmic reticulum-Golgi intermediate compartment. Endosome, multivesicular body. Nucleus.
Sequence:
MDQRLEYQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQDPAAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEGKPQPQQDSLMHLLIPTLFHMKYPVESSKSASPFNLAEKPKTVQLLLDFMLDVLLMPYGYVLNESQSRQNSSSAQGSSSNSGGGSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIVKFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKSKQSLIDWNNPAIINKMYKVYLGDIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTNSKLRTLSLQFVHHICITCPEIKIKPLGPMLLNGLTKLINEYKEDPKLLSMAYSAVGKLSSRMPHLFTKDIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEGAQRTLMEALVASYLIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGDPREEVHGEAQRVLRCLPGRNRKESTSEQMPSFPEMVYYIQEKASHRMKTPVKYMTGTTVLPFNPAAFGEIVLYLRMCLAHSAGVVPTSQSLADMQDHAPAIGRYIRTLMSSGQTAPSSSNKSGETNPVQIYIGLLQQLLAGVGGLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMNSSKEEMRELAALFYSVVVSTVSGNELKSMIEQLIKTTKDNHSPEIQHGSLLALGFTVGRYLAKKKMRMSEQQDLERNADTLPDQEELIQSATETIGSFLDSTSPLLAIAACTALGEIGRNGPLPIPSEGSGFTKLHLVESLLSRIPSSKETNKMKERAIQTLGYFPVGDGDFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAAIGTSSVAARDAWQVTEEEYTPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTLVETLMTGKRVKHEVSGETVVFQGGALGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETLFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGAAGQRTIAALLPCLLDKGMMSPVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQEKAAMDSARLSAAKSSPMMETINMCLQYLDVSVLSELVPRLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLNGWYMEKEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNLWTEVWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGMILTALLQGLAGRTWAGKEELLKAIACVVTACSAELEKSVPSQPSTNEILQAVLKECSKENLKYKIVAISCAADILKATKEDRFQEFSDIVIPLIKKNSLESSGVRTTKNEEENEKEKELQLEYLLGAFESLGKAWPRNAETQRCYRQELCKLMCERLKLSTWKVQLGVLQSMNAFFQGLMLLEEEHADPEALAEILLETCKSITYSLENKTYSSVRTEALSVIELLLKKLEESKQWECLTSECRVLLIESLATMEPDSRPELQEKAALLKKTLENLE
The following text describes a protein:
Function:
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules. May be involved in the regulation of formation of solid surface-associated biofilms and pellicles according to environmental conditions.
Sequence:
MDFGLATTLYPDEYNYQTDAYSPTSSPVDLVQVIQQLHASLDPRTVFACYGKVLGQHLPIQGVRLQSEQHKLSWGKRYGISLKRQIICGGTPLTLQYQLLTPLTPSQSICLQEIEPLLLQPLLNAMQYQEMSMQAMFDALTGLGNRHYYSQSLKNAVARAQRKQGSVSLIVLDLDNFKKLNDKYGHKCGDYILKEFGDIIRSSIRSTDQAFRIGGDEFVVIVQGNIHAAGLLCERIVSATNTHASFHQFGVSCSLGAAEASETMEAEQLYEQADKTLYQAKASGRNCYKLSPTQLS
The following text describes a protein:
Function:
This protein is probably a serine/threonine protein kinase.
Sequence:
MHRRQFFQEYRSPQQQQGHPPRSEYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQLIAECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKIKNGKCDTVPEYYSRGLNAIIHSMIDVNLRTRPSTFELLQDIQIRTARKSLQLERFERKLLDYENELTNIEKILEKQAIEYERELSQLKEQFTQAVEERAREVISGKKVGKVPESINGYYGKKFAKPAYHWQTRYR
The following text describes a protein:
Function:
Tumor suppressor involved in maintaining genome integrity. Influences gene expression and mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MRSRSRSRSRQRERRRSDSRARSRSERRTYQKPQHRRSVSRERKRERDRELHRERTSNRSSRRSREKDAVPRRRRTRSSPSRSSSSSSSDRSSSSRSPSRSRKSRPKSVERWPNDRYHENNDRRQNPFRGRAPEGSFINDPAEPSFRSQHRGRGSSNHQFKGDSKAVNARRNQRVLIGEEGVPEVWGKSPSRPETDDVELVKGSYIGPKKKKKKGKRKHKKSEKKSKKKSKKSKKKKSKQESSSSSSSSSSEDSSDESSSSSSSSSSDSEDESEEEDVWLEKTADGIKKPKKKKSSTSKKDKKSKKKKKKRKSEAEKSKKSSSSSASKSKNKESASHNDEDVGPSLRPGGSLNQKDFGKALLPGEGAAMAAYIAEGKRIPRRGEIGLTSDEIANFESVGYVMSGSRHRRMEAVRIRKENQLYSADEKRALAMFSKEERQKRENKILSQFKDMIHSKLQAKDKK
The following text describes a protein:
Function:
Self-incompatibility (SI) is the inherited ability of a flowering plant to prevent self-fertilization by discriminating between self and non-self pollen during pollination. In many species of the Solanaceae, self-incompatibility is controlled by the single, multiallelic locus S. This stylar glycoprotein is associated with expression of self-incompatibility in potato.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MAKSQLVSALFVFFFSLSPIYGDFDYMQLVLTWPRSFCYPRGFCNRIPPNNFTIHGLWPDKKPMRGQLQFCTSDDYIKFTPGSVLDALDHHWIQLKFEREIGIRDQPLWKDQYKKHGTCCLPRYNQLQYFLLAMRLKEKFDLLTTLRTHGITPGTKHTFKKIQDAIKTVTQEVPDLKCVENIQGVLELYEIGICFTPEADSLFPCRQSKSCHPTENPLILFRL
The following text describes a protein:
Function:
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. Acts primarily on non-coding regions of protein-coding genes including introns and untranslated regions (UTR). Required for normal chemotaxis. Edits the 3' UTR of clec-41 which is required for normal clec-41 expression and for chemotaxis. Plays a role in determining lifespan. Not required for RNA interference. Likely to play a role in determining whether a dsRNA enters the RNAi pathway.
Miscellaneous:
MISCELLANEOUS: Can prevent somatic transgenes from inducing gene silencing via the RNA interference (RNAi) pathway. This may occur due to A-to-I editing of transgene-derived dsRNA, preventing transgene RNAi.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSVEEGMEVELKSEKMDLDDNIPDFVKETVERSGKNPMSLFSELYVHMTGNTPVFDFYNRNQPNGSMKFICVVILNGERIEGNVKSKKKEAKVSCSLKGLEVVLKHVSEYVVPAVKFEEKTTFFEMLREHTYAKFYELCKNNALIYGFEKVIASVFLKINGNLQIIALSTGNKGLRGDKIVNDGTALIDCHAEILARRGLLRFLYSEVLKFSTEPPNSIFTKGKNALVLKPGISFHLFINTAPCGVARIDKKLKPGTSDDLQNSSRLRFKIDKGMGTVLGGASEFEAPQTFDGIMMGERMRTMSCSDKLLRANVLGVQGAILSHFIDPIYYSSIAVAELNNADRLRKAVYSRAATFKPPAPFHVQDVEIGECQVEDTEQSTSAAARSTISSMNWNLADGNTEVVRTSDGMVHDKDMSGADITTPSRLCKKNMAELMITICTLTKTSVDYPISYEELKAGSQEYAAAKKSFITWLRQKDLGIWQRKPREFQMFTIN