lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.
Miscellaneous:
MISCELLANEOUS: Preferentially activates HRAS in vivo compared to R-RAS based on their different types of prenylation.
Subcellular Localization:
Cytoplasm. Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Translocates to membranes when activated. Found both at cell periphery and along the axon of neurons (By similarity).
Domain:
The Ras-GEF domain and the N-terminal Ras-GEF domain form a Ras-binding site and mediate Ras activation; The IQ domain mediates the calcium-dependent interaction with calmodulin but is dispensable for the Ras-GEF activity; The DH (DBL-homology) domain mediates interaction with RASGRF1 and probably EPB49 and is required for RAC1 activation.
Sequence:
MQKSVRYNEGHALYLAMLARKEGTKRGFLSKKAAEASRWHEKWFALYQNVLFYFEGEQSGRPAGMYLLEGCSCERTPAPPRTNAGPAGARDALDKQYYFTVLFGHDGQKPLELRCEEEQAGKEWMEAIHQASYADILIEREVLMQKYIHLVQIVETEKIATNQLRHQLEDQDTEIERLKSEIVALNKTKERMRPYHVHQEEEDPDIKKIKKVQSFMRGWLCRRKWKTIVQDYICSPHAESMRKRNQIVFTMVEAETEYVHQLYILVNGFLRPLRMAASSKKPPINHDDVSSIFLNSETIMFLHEIFHQGLKARLANWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQVLANCKQNRDFDKLLKQYEANPACEGRMLETFLTYPMFQIPRYIITLHELLAHTPHEHVERKSLEFAKSKLEELSRVMHDEVSDTENIRKNLAIERMIVEGCDILLDTSQTFIRQGSLIQVPSVERGKLSKVRLGSLSLKKEGERQCFLFTKHFLICTRSSGGKLHLLKTGGVLSLIQCTLIEEPDGSDDDPKGSGHMFGHLDFKIVVEPPDAASFTVVLLAPSRQEKAAWMSDISQCVDNIRCNGLMTIVFEENSKVTVPHMIKSDARLHKDDTDICFSKTLNSCKVPQIRYASVERLLERLTDLRFLSIDFLNTFLHTYRIFTTATVVLAKLSDIYKRPFTSIPVRSLELFFATSQNNREHLVDGKSPRLCRKFSSPPPLAVSRTSSPVRARKLSLTSSLNSRIGALDLTNSSSSSSPTTTTHSPAASPPPHTAVLESAPADKAGDSADMSPCRSPTTPRHLRYRQPGGQVADSAHCSVSPASAFAIATAAAGHGSPPGFNNERTCDKEFIIRRTATNRVLNVLRHWVSKHAQDFELNNELKMNVLNLLEEVLRDPDLLPQERKATANILRALSQDDQDDIHLKLEDIIQMTDCPKAECFETLSAMELAEQITLLDHIVFRSIPYEEFLGQGWMKLDKNERTPYIMKTSQHFNEMSNLVASQIMNYADISSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLKKTWAKVSKQTKALMDKLQKTVSSEGRFKNLRETLKNCNPPAVPYLGMYLTDLAFIEEGTPNFTEEGLVNFSKMRMISHIIREIRQFQQTAYRIDQQPKVIQYLLDKALVIDEDSLYELSLKIEPRLPA
The following text describes a protein:
Function:
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
Domain:
The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
Sequence:
MTVNHRLLDSLTYPGGIPPYQCFDVYIPLAAPPKLTQLVTYVHGGAWRAGDKADRHSVGLIGNLSSQFPTAAICSVNYRLSTGKVNPESDVKHPTHNADVARAIEHVKTLPELKDIDETYLIGHSVGAFICLSLAGILEPPSPEAPRLAPSTCKNIRGLILLDGIYDLVKLLEEYPSYNDFVAGAFQEKDIDRLTYLEDVSPLSWSSSTVNPTTCPRILILHSRQDSLLTIRQSELAAIILESKLSLGNKLESDFESVSGDHDDLLLSPELASRIKSFIAGSK
The following text describes a protein:
Function:
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Essential for mesoderm formation and axial patterning during embryonic development. Activates the activin-like signaling pathway to induce dorsal and ventral mesoderm in animal cap ectoderm. In addition, also dorsalizes ventral marginal zone (VMZ) tissues during gastrulation. Acts in a downstream signaling cascade via cripto and cer1 to mediate cardiogenesis in embryonic mesoderm. Directs the orientation of the left-right axis by driving the left-specific gene cascade in the left lateral plate mesoderm.
Subcellular Localization:
Secreted.
Sequence:
MAVLGFILSLTILSLGHGMPTLLHSKEVRFPLQGFTQRLKASLVHHGKRLPHDMKYPVYMMHMYQNLMSGKFKDLSIQGEPALLESDTVLSLIAKGCTQVDNRWTLLFDMSSVSISSELRLAELRIHLPSFQRFQNVTLDIYHTKRNVERLFLGSVTIDSLVTPGSSWKVFNLTQMLHRYLYHKERISSDEYTDLLATSHEEQKCNGLLAERIMLVVFSTDRLSSKLTGSPSLIETVESSKYIITEADTRDTGRRRHRRNHFDQNSIIRSGFHSRPVGDDKTLCKRVDMIVDFEKIGWGDLIIYPKRFNAYRCEGSCPIPLDENFKPTNHAYIKSLVNFFNPKRVECPSCVPVKMRPLSMLMYEGDEIVLKHHEDMIVEECGCY
The following text describes a protein:
Function:
Acts as a nucleation-promoting factor by activating the Arp2/3 complex to induce actin polymerization. Participates in both linear- and branched-actin networks. Functions in linear-filament (bundled F-actin) by acting downstream of Rho1 and regulating actin and microtubule organization during oogenesis. Nucleates actin in an Arp2/3-dependent manner and exhibits F-actin and microtubule bundling and cross-linking activity in the egg chamber. During embryogenesis, acts downstream of Rho1 to activate the Arp2/3 complex which is necessary for the developmental migration of tail hemocytes anteriorly along the ventral midline. Its function in hemocyte transmigration is independent of the WASH complex. May play a role in endosomal sorting; its assembly in the WASH complex may regulate its nucleation-promoting factor (NPF) activity.
Sequence:
MEESPYLHSPYQVAIIATDLHHEDTIIQAAQSLDCLHKTINSIFERIDARLARNGSKVEDINNRVKRAQAKIDALVGSKRAIQIFAPARFPASDVLAPLPATFPQVAANPLMEQQVDQLPQGTYSSHSAADQKPDDADIFFHVRGDREQESPLVAERKITNRTAGLGILPAGGVRSVPSLMRFNTNEFAYGEDLNAWKRSLPPQNARRVASQSTQLTGEKQLAPAPHSLAHGTTKLATPAGDLRYNPAALAAPAIDVPLDLPDLPGIANDLQYEPVEEQTPIAPSQQFGDLPELPDLGLEEQDIIVQAIAAQTHIPGPVRRKSVGQCPSPVTAAPPPPPPPPPPPPPPPPAQTSAIPSPPPFPTKGAVKPLSPSLATPLNMPQPPPATEDPRSELMAAIRNAGGVHGGRLRSPAAAPLDVVDNSRSKAGGAVTGDLMADLHNKLMLRRKGISGSQNPVEATAGNPLMQQLSRVIPPPVQPRKGSKSSDEHSEDDEDGWN
The following text describes a protein:
Function:
Involved in the biosynthesis of labdane-type diterpenoid including cleroda-dienols, and peregrinol lactones and furan derivatives, dopaminergic diterpenoids that can bind to dopamine receptors in the human pituitary gland, have probably ability to lower prolactin levels, and are used to treat menstrual cycle disorders (e.g. premenstrual syndrome and mastodynia) (Probable). Terpene synthase the catalyzes the conversion of peregrinol diphosphate to viteagnusin D and 9,13(R)-epoxy-labd-14-ene, and of syn-copalyl diphosophate to vitexifolin A.
Subcellular Localization:
Plastid, chloroplast.
Domain:
The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
Sequence:
MSLRFNLIVTPFSNHRIRNRRETFPAQEFPVATSKSAVKVKCNLITSTDLVGKVREKINGKVDNSLEVPAIHPVDIPSNLCMIDTLERLGVDRYFQSEIDGVLEETYRLWQQKEKDIFADVTCRAMAFRLLRVKGYEVSSDELAPYADQAHVNLQISDVTAVIELYRASQERIYEEESTLEKLHAWTSTYLKQQLVSGTISDKKLHKQVEYYLKNYHGILDLVGIRRSLDLYDIDHYQILKAADRFRTICKDLLAFSRQDFNNCQAQYQRELQLLQRWYEDCRLDKLNYGRDVLRISYFVSSAIIGDPELSDARLAFAKYCVLTTCIDDFFDHAGSREESYRILELVKEWKEKPAEDYGSKEVEFLFTAVYNTVNELAEMAYVEQGRCVKSLLIKLWVELLTSFKKELDSWTDDTALSLDEYLSSSWVSITSRINILTSIQFLGLKLSEEMLSSQECTDLCRHGSLVVRLLNDMQTFEKERRENTKNSVSILLEAPKHEGAITEEEVISKIKEIVEQNRRKLMQMVYQRGTIFPRKCKDVFLKSCRGGYYLYSNGDEFTSPVQIMEDMKLCYEPLTFHPLEANNGGNKN
The following text describes a protein:
Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Sequence:
MKFTSTDNIEVDRQDQQKINTFSRLNMQYHELIRLNQARKDELTRLSDGKDEMELMDDDEKIPFKFGDSFIRVSVDKARTLIDEQVANVKKQFEEDTKKIEETHKQMNNLKAKLYAKFGSQINLDDQ
The following text describes a protein:
Function:
Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
Subcellular Localization:
Nucleus.
Sequence:
MHSHLRGHQTLLRLVGKRRRLPPEVQSNPQSSTLGPSDLPNVPPTPLSPEIDNTRKSGKEHTWVNLGGKENASSSDQSPTCPICGRSLPGADGAINAHIDACLARGSAASANSRPPRKTTQTTLAAFTSPRAKLGPGSKSLPSTTSKGLADTKGLSSPQTPGYKRSVSLPATLPLIDPWKDAGIEPGESLGAKRRKRAGSSVVCDESESRGGRGLDATAKGGLCNVDTGRGCLEPAPVGSKSREAVPIARGVRDEPQLKSGHSEFDSQVERPGAFHSPVVFPGGPCENGLRSDPTLEESSPPPNSEPTHLPKELDTWAVRQWRFEDAASLCTVGRPIRLVREPDNPKDGNAILVTVGGAPKAKAVDAKLGAWKESELQGRREATSDRGPADSGRPKQGLSEKRRGADESGELRASNGSQSNGSPRRRREESREDSLGKSGDDVSNTAPAPTRTSPRKRTKEAFAARQIDTEPVREAKAKQPAKKGGVDDPRVIGYLPAVIAEHLAPVMDRFGTAFGGEVTVRPQCAGAAAGVRIRRPVSEGRGGCDGELVGGLEAGRESEDRIGGRLEDGRAEGSASEDGSGGRGVGRECGSGEDTKSAIEAAHERSSRGAELRAAEGVKGEGGTESGTGGRGLEPEGAPCFEASAGGPSGVEGTEDVDRQRHVAAVDSHWRSACEAAARARAALVADPSLPKYQGNFLYMVRTVLDADGHLFSDDEAALLRGIGGVSGEGQRLVVRLFQRKGPWFRVSNLSYADVRDVPIAIQELLSRGYLLSSVQSPIPGTDSGPGGKYEASEEAGPSVIEASGANNRGSDGAGEATGGKNRGTEEVAGGKNRGTEGGLDARARRRSQRLAGTSADRDAETESGTGFLVSEVQRGASGSIGGISFSGGGSEPRWEPRAPEVRDAGYVRDRVGVLNVGELRELLCALGLKTKLEVNGAKRDELLRWIVDAACDARQTTPWGQGCHVAVMEKVAELAGESVRLPEGLHHLLWRVQRLFFLNGEQDLSAFLLVDMGLCKYPPYRCSRTRPVFRTRADLLAYEQALDVAQRMDEAVEAADTAAALRLLAAARRGLTQRALSANASLRGATSGRQSAGLETDGQDASRVGAPPGEERGTVRLEGDAMTEFGTEGGLNNGRAMSAERFRGAEVPSTVEAFSVGPIEGTEPIGRQRGHCCSIVRGGESRLGPEEIEERKRLAGEMPKLGREAEPCDGCGREGPVLQSAGVGLRAELGCHVSGLQGDTCAKVEACTIAHAQVTERFVDSARKVSSQKMGTVEVRETTVVHREQVGVAANAFEALKGQHTGTKVPLLVESRMETDERVELNPSANLEDRQSPELGPAPLFVARFAAGWVYSVVATVGVSILEKEKRYGEAVTVLRQLLSGNHSRGRRGQWWGRLSINLDHLGRKEESLQTAEAGVSDPWVRGGDRLALQRLRRGRTGAGVVRERRRGGWEGVHSEGGVWCTLFGLLMWEVLFADVADVFRTPFQTAPLDLDTDAFFPSREAAILERLRLIQTGDVASLLAVRWATSAGTWCRGVNWERHTLEELQTIAGCVGNQGLAAVCRLLAEDHAGWAGGMPDLLLWRENRVGLNGVRFEEERGRVGGLRSEERPARGVQLPSGLEASWDCQEVGLVECNGINTGRTTSSQEGVTEGDGGIGGLREGVDFWVKREAKLVEVKGPRDRLSEQQRAWIGALQAAGIAVEVCKVVECEESKGAKGKQAGKKRK
The following text describes a protein:
Function:
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
Sequence:
MSIENSSGSSTAEECGAHVKIEEDFLNSGRTGRRNAIPDIYCPQSRVSTAELPTNFARLSCEESGQTQVSSSTNLGPNS
The following text describes a protein:
Function:
Key enzyme of fatty acid beta-oxidation. Able to isomerize both 3-cis (3Z) and 3-trans (3E) double bonds into the 2-trans (2E) form in a range of enoyl-CoA species, with a preference for (3Z)-enoyl-CoAs over (3E)-enoyl-CoAs. The catalytic efficiency of this enzyme is not affected by the fatty acyl chain length.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MRILRQYAMLSKRLFLSPFIWKAGSSRFLCSRADGKFLQTTKNSAGGFVVVKMQRPPANGLNLDFLTELTILLEKLEDDHSCRGMILTSSLPGIFSAGIDMSELTLSENHGPEHVTAFWQALQIFIINLYKTHLVTIATITGHAPAGGCLLSLVCDYRIMAAGNYTIGISAVRAGLFPPAWIQLLLADTIGRRQAELSVLQGKLYSPQEALKLGLVDKVVPETELQPAAESELRDWLQVPDAARILTKSNLRRKLLQTFQHNREREVEDITRFVQTDSFQNNLKEFMRNLKNRSR
The following text describes a protein:
Function:
Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate.
Subcellular Localization:
Lysosome.
Sequence:
MPTPGSGRGFLWLGLVLSSVCVALGCETQANSTTDALNILLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHAGNFSTIPQYFKENGYVTMSVGKVFHPGITSNHTDDSPYSWSFPPYHPSSEKYENTKTCRGPDGELHANLLCPVDVVDVPEGTLPDKQSTEQAIQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDSEVPDGLPPVAYNPWMDIRQREDVQALNISVPYGPIPVEFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIVAFTSDHGWALGEHGEWAKYSNFDVATHVPLMFYVPGRTASLPEAGEKLFPYLDPFDSASELMEPGRQSMDLVELVSLFPTLAGLAGLQVPPRCPVPSFHVELCREGKNLLKHFRFRDLEEDPYLPGNPRELIAYSQYPRPADFPQWNSDKPSLKDIKIMGYSIRTIDYRYTVWVGFNPDEFLANFSDIHAGELYFVDSDPLQDHNMYNDSQGGDLFQLLMP
The following text describes a protein:
Function:
Involved in the cell surface expression of neuronal nicotinic receptors. Binds RNA.
Subcellular Localization:
Nucleus inner membrane; Multi-pass membrane protein.
Sequence:
MLPSTSVNSLVQGNGVLNSRDAARHTAGAKRYKYLRRLFRFRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVSTIGFGFVLDMGFFETIKLLLWVVFIDCVGVGLLISTLMWFISNKYLVKRQSRDYDVEWGYAFDVHLNAFYPLLVILHFIQLFFINHVILTDTFIGYLVGNTLWLVAVGYYIYVTFLGYSALPFLKNTVILLYPFAPLILLYGLSLALGWNFTHTLCSFYKYRVK
The following text describes a protein:
Function:
Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia.
Subcellular Localization:
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MTNPCTVALELFGMLIGAGGWFCSLAATIMPQWLSRSTELFATESFEQGLWEVCVIQEVAGMECRPYDTILGLDPTVMLARILMCMSNATGLLGILLAIPSMSQIKCCKGEEGRKTKRGLKISAAVFLCIAGLLVLTPISYVAHDTVMRYFDESVPHVVPRSEFGDALFIGWSAGLLYIVASVLLFASCTDSGNSEPHLVYHHRRQDTRTLDRSGKRTEYV
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MEIELVTVKEETGPEIPSICPFCQEDLPTLAGPTGHVPQCPGCKSFVLEPQNWLPDNPEAMGHPTERPYTCSFCSKRFKRASDRRDHERVHTGERPYGCGVCGKRFTQSSVLSGHMRIHTGERPFHCGVCFKSFNNGSNFRKHQRIHSQLFGHCNTRDDEKDCDLFLGKKQSQFTEGQNGYQVTQELNNGENRRNQDPKEWQGISSNNRIPQNGSLRQPSDNMAYFKGRGLRQDSSHQTRQSSHGCIGVKMEDSKYDYGCLGDSGECSQGSEVTENGHSFQPLRNVSGENDTKALRPNKAGGSHTREEHKQLEENSNKLQLDGSSFGKGLLQADGDRKGIHKQGQESRVRSYLLRRPNGDYLKGLKHRSGDGTGPNMRQNGTSHLSGLNPNMDVSILEPRQNGSNADVADDLRHQNPGQFEEVTQDGGTNKEKWMNVQVDTPKNINVVAPKVSSWTRANESNVLTWEEPNIRIMKEKDEFEDCSTIGISNNASPWQRESPEPWSLPCDISASSHSHSQHQFRSVSHHWEEDGSSPLSFPFQEPETYRQHSLPDLDSKPFLCFACPKQFRRATDLKEHLRVHTGERPFGCNVCGKRFTQSSALVTHRRLHTGEKPFECAVCYRRFNNSSNFAKHRRLHGQEGTRHGGKVIVKDLWSVKPH
The following text describes a protein:
Function:
[Bombinin-BO1]: Has antimicrobial activity against Gram-negative bacterium E.coli (MIC=26.3 uM), Gram-positive bacterium S.aureus (MIC=26.3 uM) and yeast C.albicans (MIC=52.5 uM). Has moderate hemolytic activity towards human erythrocytes at a concentration of 52.2 uM; [Bombinin H-BO1]: Has no antimicrobial activity at concentrations up to 161 uM. Has moderate hemolytic activity towards human erythrocytes at a concentration of 40.3 uM.
Subcellular Localization:
Secreted.
Sequence:
MNFKYIIAVSFLIASAYARSEEYDIQSLSQRDVLEEESLRKIRGIGSAILSAGKSIIKGLAKGLAEHFGKRTAEDHEVMKRLEAAMRDLDSLDYPEEASERETRGFNQEEKEKRIIGPVLGLVGKALGGLLG
The following text describes a protein:
Function:
Small subunit of the arginine-specific carbamoyl phosphate synthase (CPSase). CPSase catalyzes the formation of carbamoyl phosphate from the ammonia moiety of glutamine, carbonate, and phosphate donated by ATP, the first step of the arginine biosynthetic pathway. The small subunit (glutamine amidotransferase) binds and cleaves glutamine to supply the large subunit with the substrate ammonia.
Sequence:
MAATTMTTTLGFVLPTSLSPRRGGFRVSVIRCSASPLTTSTGSAASGVVEKPWSTYDARLVLEDGSIWPAKSFGAPGTRVAELVFNTSLTGYQEILTDPSYAGQFVLMTNPQIGNTGVNLDDEESEQCFLAGLVIRSLSISTSNWRCTKTLADYLTERNLMGIYDLDTRAITRRLREEGSLNGVLSTEQSKTDEELLHMSRSWDIVGIDLISDVSCKSPYEWVDKTDPEWDFNTNTRDGKPYRVIAYDFGIKHNILRRLSSYGCQITVVPSTFPASEALKMNPDGILFSNGPGDPSAVPYAVETVKELLGKVPVYGICMGHQLLGQALGGKTFKMKFGHHGGNHPVRNNRTGQVEISAQNHNYAVDPASLPGGVEVTHVNLNDGSCAGLSFPAMNVMSLQYHPEASPGPHDSDNAFREFIELMKRSKQSS
The following text describes a protein:
Function:
May be a transcription factor for genes having (A+T) stretches in their promoter and/or enhancer regions. Binds to AT rich DNA (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MGFPRILSKNNKIYTKLGEFCLSGDSFWIVCHTCQEELQTQDAFWKHIQDEHNFLHGLAKQEHGRNSSYCLPDVDAATAPANQTALPVPLALYHCAKYSEEEQREVAAAVELHEAQQQQQQQQQQQQQQQQLQQQQQQRDSAELQAVTAAAESSARSNNSGSGIDIKVEPTSLTLTSEIQVAAAAAAAAAAAGAAAAGAVTANTTIYHLSQVVPGPPPPPPPTPCFVTTPTAGGVSTTPPHPALAGPVGAGGNGGNGANATVMQQACGTLGMPLLGVAAGQAELVAKESNSTTASASSAVSSDDGERWYICDYGACGLKFKYKSRMELHRVVHSKERRFNCDMCSASFKQSCNLSTHRKKKHSLRGIKSELLPQRF
The following text describes a protein:
Function:
Its physiological role is not yet clear.
Sequence:
MAEPLKSVDYEVFGTVQGVCFRMYTEGEAKKRGLVGWVKNTSKGTVTGQVQGPEEKVNSMKSWLSKVGSPSSRIDRADFSNEKTISKLEYSNFSIRY
The following text describes a protein:
Function:
Involved in DNA mismatch repair and meiotic recombination processes. Facilitates crossovers between homologs during meiosis.
Sequence:
IKRYASSSHTHPNFTTRSSLPKRADYESKPLPITEQEDEQEQSEIYLCVLWYGGELGIAYYDTGDCSIYFMAESPDNKDLKLLQKVVDEVLPTYILSSAKQDQSIASFFTNIKTVTEEKQGERKPEVVFYPNMDFGLEVSKQRILSRQFPFVPSHMTATEKILYLSSVIPFESPLVVRALGGLLKFLDRKRPGVELEDSHIAVPILAFKKFVLTDIVNVDQDTYCVLQIFKSEIHPSVYKQVSGKKEGLSLYGILNHCRCKWGEKLMRLWFMRPTRNLTELNKRLDVIQFFLLARNHEIVLTLQECLKNIKNVPLILRRMALSNTKVSDWQALYKTVYSAVCLRNTCRSLPSTIDLFQTISQVFTDDLHYIASLISKVVDFESSIAENHFTVRPNVDAIIDEKKRKVMGLSDFLTDVTVDEDQETLIMYQLQTKILEKSAVLNDVIEYTAHLDVLLSLAVMARENGYVRPHFSHSHMIRIKDGRHPLMELCAKTFVPNSVESCETSGRIKILTGPNSSGKSIYLKQVGLITFMALIGSYVPAAEAEIGAVDGIYTRIHSRESVSLGLSTFMIDLNQVAKAVNNATERSLVLIDEFGKGTNTVDGLSLLAAVLRYWIKQATNCPHIFVATNFHSLVQLKLLPTTPLVQYLTMDTHQDGDELVFFYQIKEGVSTVSHAANIAALAGMPPKVIARGIEVSELLRNGKPIQRPDHSSKEKQLQNCKALVDKFLSLDLDDPHLDLKEFMNKEVLPSSASIL
The following text describes a protein:
Function:
Plays an important role in the elongation step of protein synthesis.
Sequence:
MSFGELACSYAVLILHDDGIPVTAEKIATLVKAANVSVESYWPGLFAKLAEKRNVEDLIMNVGSGGGAAAIAVAAPAGGAAPAAAAPAAEEKKEEPKEESDDDMGFSLFD
The following text describes a protein:
Function:
NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MISIDLLDNSGTSMPADTSIKLHEVIKFISKSKKMTVLTGAGISCNAGIPDFRSSDGLYNMVKAKHPKAVVRGQDLFDISLFRDEMSLSVFCTFMESLYKSSLNAKPTETHKFIKILKDKNKLLRCYTQNIDCIEQHINLKLGINLQEFDNNKFKQVWNQLDVVQLHGNLHKLSCTNCFSQFNWNEEFQTLLANGLNPECSKCMDKYQQRLYSGKRLTGQTIGLLRPDIVLYGEHHPQMEILTQGLNSDLKSRPDCLIIMGTSLKVAGVKSLVKSLSKIIHNKGGKVIYVNKTKLSASSWKNYIDYEVVSDCDEFVRMLKTEIPDLFLTQEQLDSEKLNQVAVKGSSLNKPIVKPEAKVKIEPGIKQEDAIQYSPEREVTIKQEVNIKQEPIVKREVESVSVKEEPIPTPPTTPHKPKQATKLKRKSPDEISANEVHSRVKRLRPRNDQLSSPASSINGSEEEEEEDEPVAKVLFENARKGITLDQH
The following text describes a protein:
Function:
Probable transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MVMMIIIYTEPEISLFPLQDRSEELSSNVENGSCNSNEGINPETSSHWIENVVKVRKPYTVTKQREKWSEEEHDRFLEAIKLYGRGWRQIQEHIGTKTAVQIRSHAQKFFSKMAQEADSRSEGSVKAIVIPPPRPKRKPAHPYPRKSPVPYTQSPPPNLSAMEKGTKSPTSVLSSFGSEDQNNYTTSKQPFKDDSDIGSTPISSITLFGKIVLVAEESHKPSSYNDDDLKQMTCQENHYSGMLVDTNLSLGVWETFCTGSNAFGSVTEASENLEKSAEPISSSWKRLSSLEKQGSCNPVNASGFRPYKRCLSEREVTSSLTLVASDEKKSQRARIC
The following text describes a protein:
Function:
Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MYEKIVIVLLLSGYISTQDVTEIIPHEISSKLPTQAGFISTEDPSFNTPSTRQDPSGTMYQHLPDGGQKARQQLVHIFSEPVIIGIIYAVMLGIIITILSIAFCIGQLTKKSSLPAQVASPEDVDPEVL
The following text describes a protein:
Function:
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.
Subcellular Localization:
Bud. Bud neck.
Sequence:
MSSSTIQAHTIQHSNLDQSAADLVLLSNSLDKSKRITDNLSKMLTGFDDRLSRLERTIVPIHNDTRTLTRINANIDQTILAVDKLLAHHDAAIHQEVVIQNGPNPNELGSFISSLDEIVKSIQTLSRTEAPVSESTLHAEKLLRTGVESLSDMFAGWVRDSTGPPLTDPVHQTADPPQPLGFSPNTINKLHKLYAYLQQLSKSLPGNQTIQDVHKEIVSAYASVRSKYVVASLKTLSDGSVEAIRNGDGFGQFSSFISCLLDMLNVEYKAVLSVFKGASTIQIKAIYSQVISASLELLSETGQSVNSVIKRSLSSYIGVAFDTYAAILEQLPRFDEEVRRPAGRKENELGDLLHAFKGSCLRSLPEFIADTKTFGEKQPVGSEASNTMTSEMTIVVVEYLKMLCQHPDMVETLLVILGDGKWIFGATNNPKTPSSAGASNDEAPLLIKYLDDALSTLYAAIEARSKNLKLRSTVASAITSVTARNGVGAIYMLNNFTYIRRELLESAVLDIYGDPLADQLNKRVRTCKVRYLEIWSPLISALMDAGGEEGKFGLGAVKSALPGQHAGAERRDVKDRFGRFNEAFEEVIQLHQAANLANNDPDLKDQLRDEIERMIMPTYAKFTQRHEGGQFSKNPSKYLKFSAEQLEERLDGLFQ
The following text describes a protein:
Function:
Invertase that cleaves sucrose into glucose and fructose.
Sequence:
MASRYTLQWIRRIIHLTLGFGKDIYETEVSFKRKTGVDFFALTGCEHGNCVAEQRAERNLVLQMLKPERDGPFEEGIFLVNISPARMDFRSFLVDNFIAILSSLVTPAQATAVMDLIEERWEEWIGEMPLKITYPALEGHEWRIVTGFDPKNTGRSYLIDQGSRFYVKYPEKPKPLIPVLRKTTTSQELRKRRDVVSNNSAKAGGGDPQSLSSYQAELPSYIIHLPASSGGGSIPVIRDVAKKTDSTRYALPALRFKTCRLLSGNVWNRELTIIQRRILRRLRNKKRSIKRKIYSRENLNSYIQSQTTRKLSLFYGDLPITEMHRGRERTSYIPFLLNPETRSDVIPVRLHFCETIPQARQPISHRRVCVNNGMVNITHFKLSHGDIISFQENDARTRGEEIKRSFYIEISVEKIIGKFLDHPWRRTKTEWFRLLKTKRGCRLLLKSRFLQQLRSSMQEEDLERTKKFGSEKVCLGSSFAEHNRMKRNLYHFKSLFLSKRRNEKNRNIPTRTRSPIVYNSSLYSNSTYCSASPHQFTKKIKIKRIELPTHYSEVNHRTPKAVVSYGPNIGHIPHDIRLKDPNLLLRSGKGRGQNI
The following text describes a protein:
Function:
Contributes to the assembly of the acentrosomal spindle and phragmoplast microtubule arrays as part of the augmin complex.
Sequence:
MSMGGDTTWVGKKPIRRIGGLSDALSIASDLGFAVAPPPSQEELQSFASSNGERGDDLIRVLRELSVVQRKIADLQVELQGRKDDKNVAHLTHVGEMQKKIETLSRITQILKDVIQNKDRIIARLQQPYSLDCIPVEAEYQKQFSELLMKAASDYGALTASVSDFQWSQNFKEPPSVWGEMLRPIPVALASCTRFFEAMSAMRESFATLQELRVGNSAVSLPTTPGGNEMTHRDSDCVTPPQGRIESSFDDLAVHKTRRQNNDQNEEEEEEEEEEDGNNNGNRRLSWPPSVKKSSV
The following text describes a protein:
Function:
Binds preferentially to highly ordered alpha-glucans, such as starch and crystalline maltodextrins. Involved in the organization of the starch granule matrix, thus influencing starch turnover by modulating the accessibility of starch polymers to modifying and degrading enzymes involved in phosphorylation, hydrolyzes and synthesis, including starch synthases (SSI and SSIII), starch phosphorylases (PHS1), isoamylase, beta-amylase, glucan water dikinase (GWD) and phosphoglucan water dikinase (PWD).
Subcellular Localization:
Plastid, chloroplast stroma. Note=Binds to starch granules in chloroplasts.
Sequence:
MALRLGVSIGAALGSSHWDDGQRVRQRDFSASVNFTAPVTSRRSLRGSRTGVRILRVSNEGRESYLDMWKNAVDREKKEKAFEKIAENVVAVDGEKEKGGDLEKKSDEFQKILEVSVEERDRIQRMQVVDRAAAAISAARAILASNNSGDGKEGFPNEDNTVTSEVTETPKNAKLGMWSRTVYVPRSETSGTETPGPDFWSWTPPQGSEISSVDLQAVEKPAEFPTLPNPVLEKDKSADSLSIPYESMLSSERHSFTIPPFESLIEVRKEAETKPSSETLSTEHDLDLISSANAEEVARVLDSLDESSTHGVSEDGLKWWKQTGVEKRPDGVVCRWTMIRGVTADGVVEWQDKYWEASDDFGFKELGSEKSGRDATGNVWREFWRESMSQENGVVHMEKTADKWGKSGQGDEWQEKWWEHYDATGKSEKWAHKWCSIDRNTPLDAGHAHVWHERWGEKYDGQGGSTKYTDKWAERWVGDGWDKWGDKWDENFNPSAQGVKQGETWWEGKHGDRWNRSWGEGHNGSGWVHKYGKSSSGEHWDTHVPQETWYEKFPHFGFFHCFDNSVQLRAVKKPSDMS
The following text describes a protein:
Function:
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Sequence:
MDPVRVAIQRLAHCFALPTCAHPGDAGLDLFAAHAVPLSIAPGRFTRVPTGIALGLPAGYMAFVQPRSGLAARHGISVLNTPGLIDCGYRGEIQVLLINHGEVPVVVSRGDRIAQLVVLPVPQVQFVEVSTLESSERQTGSFGSSGY
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MPQVKLHKHYVPIILLSKILGIAPISYKNSNVNYSKIGIVQTVAYFVIFIILTIVFFEKRSALSPFELIQIRTINFVATFRTIANIILMAVLFLGTFIGRAKFLAILKQMRNLEPEFLKLDQLGATVRNNRQIRRMVVFLIGVSLSFNLFGDLLTLFIKEELDLVWREVCTFVVQVYPRLVVNTINLTFLTLLMILEGRFRVINDGIQALINDSRKVTRFPTELTFCNKIKHLVNLHKNLVKVAKDHNSLYSLHLLLWITVTFILLVGDSYIVMYVFFFHLSDVRYVMVVYLLKNVVLYGLELFILAKIVTDLCQEANSTKKLIVKIKIDIDKEDERNEVISSALKLSQNELEITACKFFSIDNALLFSVIQKKLIVCLLKNVVLYALEFFILAKIVTDLCQEANSTKKLIVKIRIDIDKEDERNEVISSALKLIQNELEITACKFFSIDNALLFSVKKVIESQKNQKSVDLTFCETLTDLIQIHKILTKITGKINAVFALQLLLWIGFNFLFLLMDSYTTAHLIFFDWKSSKLYPVSLMLLNVFSYCFYIFYLSRRCERVCFEANRTAFIVAGTSIDFHKEEERNLIITGILNLMKNKLELTACRLFSIDNTLLFSVCGAASSYLFIMLQFDLEAFKNLKTRNSTNSSF