lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
Subcellular Localization:
Cytoplasm.
Sequence:
MDTLTHLSHTLREAMSDIVPESHPEHPFNLIPELCRKFYDLGWATGTGGGISIKMGENYYIAPSGVQKERIKPNEIFVLNASQDVVEEPRTEKQLKISECTPLFFNAYRMRGAGACLHTHSANCVLISLLCDREFRISHIEMIKGIINNETKKALGFRDTLVIPIIENTDFERDLTASMAECMERYPESCAVLVRRHGMYVWSDTWQKAKGAVECIDYLMGLAIRMRTLGLEWEPKDVK
The following text describes a protein:
Function:
Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
Domain:
Consists of a six-stranded anti-parallel beta-barrel core structure with an unstructured N-terminus in apo-form and a C-terminal alpha helix. In the holo-form the C-terminal helix is displaced by the ligand, thereby opening one side of the beta-barrel as a binding site, and the N-terminus containing the RXXXR motif wraps around the ligand and in turn ties the C-terminal helix in a loose conformation. The structural rearrangement upon ligand binding creates a significant change in surface charge distribution.
Sequence:
MSDQHDERRRFHRIAFDADSEILQGERRWEVLLHDVSLHGILVGQPQDWNGDPQRPFEARLYLGLDVLIRMEISLAWARDGLLGFECQHIDLDSISHLRRLVELNLGDEELLERELALLVSAHDD
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
Sequence:
MDKSKNFSEELAEKDQIVNKTSPTYDSLNLYFKCISSFPVLSKQEEKNLAKTITDKKMELIKELLHIPFVQKKIYELSNVFSKNPEKAKEMLDDEEEIDIEQIKERFIKVSENIKKIMRRKKTTKEFLKKIFDIPLRDELTNMFVEELDKFRREIIKGENLQPITGMTNEEFLDHFMTIKKIFNEFTEAKNKMIESNLKLVVSIAKKYTGRGLNLEDLIQEGNIGLMKAVEKFEYKKGFKFSTYSTWWIRQSINRAIAEHSKTIRIPVHVIDNICKINKIYRELYQNSENEPDIEEISLNLNIPSDKIADFLAISKEPVSIDMSLRDDDSLLKEFIEDMNSPNPYEEALHDDLKHLIEKVFSLLSKREKEILMRRYGINEEKPKSLDEVGKEFSVSRERIRQIELRAMRKLKRLCRLKWLREFIRES
The following text describes a protein:
Function:
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance. Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MAVYVDHRTEAPDSVASPSLITWHSVHPLLAVASISTASGGCVDIYLEQGEHEPDAHIERSFQVTSLSWHPSRLILAAGWETGEVVILNKQDKELHTVPPNHNAKITILNWSSNGSRLVSGDRHGILFLWRMDQRGRVQGPPMLKHEYGKCLSHCIFRPPPPGEDFLQLAKAAVSGDEKALDMFNWRKAGTEAPLKMGLQEGLSFFITLTDGSVHYVNEKGKTSHVLSADNLVQKLLFMEKRDALVVVTENLLLSLHTITLEGDAKELMKVKLGGKTGNSADIILIDHSLIVTAMGETVLRFWDLDRGENYVLSPDVQFGFEAGECMNCVSYCSAKGLLAAGTNKGRVAMWRSVSVSSQSTGALEGKEKWKLQASTELEGNITQIKWGSRKNLLAVNSISSVVILSEQAMSCHYNQQVAAVQVSPSLFNVTFFSTGTTHNLHVDMTVNGVFTTKDAVVFWNGKQVTVFECSEDTLRNAGSFLCDSPVLSMHGENLYTVEPHRVQVRTWQGTVKQLLVFSEAEGNPCLLDVCGNFLAVGTDLAHFKIFDLSRREAKVHCNSKNFSELFPGLGNIASVKCNANGNKVSILVSKANGSTDSKICFYDVEMDKVTLFDFKAERGIGREKLSSGHGIDRSVVEYPDLHNHIPVCHFWDCSEPRLFVCETIPETGVRSPSQKNNQTESMLDVWVVSFFSTEEHGLLLQDSFPLPSLYEVLLGIDVPHYYFAKKPGETGKGQAESGSKVLQMASRQPMRDFIGLGDCDKATRDAMLNFSFYLTAGDMDEAFKSIKLIKSEAVWENMARMCVKTQRLDVAKICLGNMGHARGARALREAEQEPEQEARVAVLAVQLGMLEDAERLYKACKRYDLLNKFYQATNQWQKAIETAEAHDRVHLRTTYYNYAKHLEAVGDHALALSHYEKSDTHRFEVPRMLSEDLQALENYVNKMKDKSLWKWWAQYLESQSDLESALKYYALAQDYFSLVRVHCFQGNIQKAAEIANETGNWAASYHLARQYESQDEIKQAVHFYTRAQAFNNAIRLCKENNLDDQLMNLALLSSPEDMIEAACYYEEKGEQMDRAVMLYHKAGHFSKALELAFATQQFGALQLIAEDLDEKSDPALLARCSGFFIEHAQYEKAVELLLTAKKYHEALQLCLKQNLTITEEMAERMTVSKDSKDLSEESRRELLEQIADCCMRQGNYHMATKKYTQAGNKLKAMKALLRSGDTEKIVFFAGVSRQREIYIMAANYLQSLDWRKDPEIMKNIISFYTKGRALDLLAGFYDVCAQVEIDEYQNYEKAQGALTEAYKCLSKAKTKSPLEQESKLAHLQSKMALIKRFIHARRVYSEDPKEAVRQCELLLAEQDLDNTIRQGDVLGFLVEHYLQVEEFHMAYQYLEQMRKRIPCTNLTYYIKQQTIEAVHRGAGIPISQALVPERSQHSSVENKDVEEEVADEVEGP
The following text describes a protein:
Function:
Seed storage protein.
Sequence:
MVAFKFLLALSLSLLVSAAIAQTREPRLTQGQQCRFQRISGAQPSLRIQSEGGTTELWDERQEQFQCAGIVAMRSTIRPNGLSLPNYHPSPRLVYIERGQGLISIMVPGCAETYQVHRSQRTMERTEASEQQDRGSVRDLHQKVHRLRQGDIVAIPSGAAHWCYNDGSEDLVAVSINDVNHLSNQLDQKFRAFYLAGGVPRSGEQEQQARQTFHNIFRAFDAELLSEAFNVPQETIRRMQSEEEERGLIVMARERMTFVRPDEEEGEQEHRGRQLDNGLEETFCTMKFRTNVESRREADIFSRQAGRVHVVDRNKLPILKYMDLSAEKGNLYSNALVSPDWSMTGHTIVYVTRGDAQVQVVDHNGQALMNDRVNQGEMFVVPQYYTSTARAGNNGFEWVAFKTTGSPMRSPLAGYTSVIRAMPLQVITNSYQISPNQAQALKMNRGSQSFLLSPGGRRS
The following text describes a protein:
Function:
Catalyzes the reduction of C16 or C18 fatty acyl-CoA to fatty alcohols.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAVITEHGGTTSSPPENNNSIGNGKHRVNGHQLSTSLTIPEFFAHKNIFVTGGTGFLGTVLIEALLDTHPDIGTIYVLVRGKRKFDPNERIRRLLQKPIFEKYSEKTLSKVVPVVGELSEPNFGFGPELLQELIDRVNVIYHSAATIKFSSPLRTAIRTNLTGTMRTIELAKQLKQLAAYIYCSTAFCNSNNRGLIAEEVYKSQFDPYEMMKMAEDDSAWEDFTDQKCKGYIRDHPNTYTFTKNLSENLLMAEMSGLPAAIVRPSIVYGTLEHPMKGWVGNANSGHLGFLAGFVKGIFRTMCGNANAVIDIIPCDYVINSSLVMGWYVGTRKLEQPEIIHCTSGEVNPLNLAEFCTIINDSVERHPPNSFVWKPVTKLRNGWRYNLFFYLFHLLPAMVFIIPEKLFGIGMPQHTAYEYMRVFQKGTKAFDYFLDKDFRYSLKNALRISALIPESDRRRYNFDASQCDWSEFIDRCLIGIRRFYFKESAVTTDWHRNYWKVFNVLYYAGYVVIFAVLYFALTLTLGLQIGLTLAVLIWGFLVWL
The following text describes a protein:
Function:
One of the extrinsic, lumenal subunits of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating a proton gradient subsequently used for ATP formation. The extrinsic proteins stabilize the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protect the OEC against heat-induced inactivation. Low-potential cytochrome c that plays a role in the OEC of PSII, required for normal function or stabilization of PSII.
Subcellular Localization:
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane. CyanoQ (PsbQ) binds to the large lumenal domain of PsbC (CP43) between PsbO and PsbV.
Sequence:
MKRFFLVAIASVLFFFNTMVGSANAVELTESTRTIPLDEAGGTTTLTARQFTNGQKIFVDTCTQCHLQGKTKTNNNVSLGLADLAGAEPRRDNVLALVEFLKNPKSYDGEDDYSELHPNISRPDIYPEMRNYTEDDIFDVAGYTLIAPKLDERWGGTIYF
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). NUP57 plays an important role in several nuclear transport pathways including poly(A)+ RNA, tRNA, and pre-ribosome transport.
Miscellaneous:
MISCELLANEOUS: Present with 9310 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Domain:
Contains FG repeats. FG repeats are interaction sites for karyopherins (importins, exportins) and form probably an affinity gradient, guiding the transport proteins unidirectionally with their cargo through the NPC. FG repeat regions are highly flexible and lack ordered secondary structure. The overall conservation of FG repeats regarding exact sequence, spacing, and repeat unit length is limited. FG repeat types and their physico-chemical environment change across the NPC from the nucleoplasmic to the cytoplasmic side: GLFG repeats are especially abundant in NUPs in the central region (lacking a charged environment but are enriched in Ser, Thr, Gln, and Asn).
Sequence:
MFGFSGSNNGFGNKPAGSTGFSFGQNNNNTNTQPSASGFGFGGSQPNSGTATTGGFGANQATNTFGSNQQSSTGGGLFGNKPALGSLGSSSTTASGTTATGTGLFGQQTAQPQQSTIGGGLFGNKPTTTTGGLFGNSAQNNSTTSGGLFGNKVGSTGSLMGGNSTQNTSNMNAGGLFGAKPQNTTATTGGLFGSKPQGSTTNGGLFGSGTQNNNTLGGGGLFGQSQQPQTNTAPGLGNTVSTQPSFAWSKPSTGSNLQQQQQQQIQVPLQQTQAIAQQQQLSNYPQQIQEQVLKCKESWDPNTTKTKLRAFVYNKVNETEAILYTKPGHVLQEEWDQAMEKKPSPQTIPIQIYGFEGLNQRNQVQTENVAQARIILNHILEKSTQLQQKHELDTASRILKAQSRNVEIEKRILKLGTQLATLKNRGLPLGIAEEKMWSQFQTLLQRSEDPAGLGKTNELWARLAILKERAKNISSQLDSKLMVFNDDTKNQDSMSKGTGEESNDRINKIVEILTNQQRGITYLNEVLEKDAAIVKKYKNKT
The following text describes a protein:
Function:
Modulates postsynaptic dendritic arbor elaboration and synaptic maturation.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MGLKLSGRYIFLVLAVHLAYLLQAVKATGKCDAVFKGLSDCMLTLGDKVANYPQDLEEKKNLDTICSYWDDFHVCTVTALADCQEGAADIWEKLKRQSKNLNIQGSLFELCPGSAGAPGQRLLFPAFLPLLMVFLSTLFILVLQ
The following text describes a protein:
Function:
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVENSPAPLPERAIYGFVLYLGSQFVFILYLVWAYVPESWLFSLGLTYWPQKYWAVAVPAYLLVSTGIGYVLLFGINMISTAPLNSTHTITDHYAKNQKHKEPQTDAIPALRDIPISEVNKMFFLTDREDCLRN
The following text describes a protein:
Function:
Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (2',3'-cGAMP) from ATP and GTP and plays a key role in innate immunity. Directly binds some unknown ligand, activating the nucleotidyltransferase activity, leading to synthesis of 2',3'-cGAMP, a second messenger that binds to and activates Sting, thereby triggering the immune response via activation of the NF-kappa-B transcription factor.
Sequence:
MASNVEDTLIKLDRLHSVDYKNDEVQLIKSKIEGIVHQISNRIGELNPILSNSVVHCGSFYHNSKINAPDEFDFLLVLNKFSQPGVCSCKPFEDPEYTHLVSLGIDNTKLNWNPQSVLEWEEDAANKQTLLQATIDSEYRNAVCSCLATMSLPDGISLTTSQKSVRRRFEGGEEFLANFKFSGPALTLLLNWKGVYYPNLNISVDVTYVIAMRGLPSFCNLDKRLPSEHLIVKAGLCADASHELLYCRMLDDTWKQTCSVLENKIICFWFKENDASNVCYRLLKIIRNLVTPVNQLGEAFLKTYALKTLFLYECEQFPDSKFWRTDELSTHLLTIFQKLLSAIQNRFLPNYFNENQNALCYPLDSRPEDENEEGENKFISSVYEAMCKIIEDIISSLEKGLASEQTLKFYFEPGQKIVIKDPDIQDALEKEN
The following text describes a protein:
Function:
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
Sequence:
MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRMHKRHVRIHPSSRTDRGVHAIQQYFHFDTELNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQHRDPFQSGLKTFIPETLDLGKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEVSDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSLQND
The following text describes a protein:
Function:
This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted by either the NarX or NarQ proteins.
Sequence:
MNNQEPATILLIDDHPMLRTGVKQLVSMAPDISVVGEASNGEQGIDLAESLDPDLILLDLNMPGMNGLETLDKLREKALSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALQQAAAGEMVLSEALTPVLAASLRANRATTDRDVTQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF
The following text describes a protein:
Function:
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLGLFAIAFIITYIISALLLLFIRVKWGLRLFGALALALIVALITLFAYEAYPILSRDGLSIFVKVEWDPVRESYGVLQALAGTLITSAIAILLAMPLSVGVVVTINEILPRQVRSFFASLVDLTATMPTVIYGLWGVFVLGPWLQSAVNFIGSLLGLGQLMTSSYSLFTAAVLLAIMITPYAAAVMREGYALVPKPIEEAIYALGATRLEAVWIKLKYIRNYVIGGLFLALGRAMGETVAVAMVVGGNFSRLVLNVFDSGITISSLIALQFPNAASYQYMLPALYAGALLLALTGLVINAAAIYILMRGQL
The following text describes a protein:
Function:
Essential for recycling GMP and indirectly, cGMP.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MTDKTAELCLKIGDEEKDDFTLEIEKLQATLQEMLDCTSSPSTSLDSTDKLPSGLAARRLIRIASEHHHISTTSSCHSDSGNSSSRDVITPFTVHGGASIGRLILIDIVRRDDLIGIVHPNDILLTIENIKVSGMVRSEVNRILEDMMREHDQIAIEILPAGAITDDICELLADRKSSGELQTIIRENLYQKTVPYTTRPPREGEVDGEHYRFVSVDDFNKLLDSGDLLENGTYQGHLYGTPRPVECYADDDMMLMGSEGLLPPNWETAYTENGDKYFIDHNTGTTTWDDPRELPPGWEQVDDQNYGTFYVDHINRKTQYERPYGFGGSSATIDQPVKYGTLPSSTNHNHNNIYSHYNSGTLKSSSSPRDSGFDSSPTRYRKFGDPPETATSSADYDHHSKMFSRSSNPLFTTDPARLGGELISTKIVKGAKGLGFTLIGNDSSSRGDEFIQVKSVLSGGPAAANGVLRSGDILVRVNGRLLLGATQKEACDVFVAIPVNEAVDIQVCRGYELFIDPANRIVTENVYAAAKSRDLHEIDIFKGSEGFGFTIADNLNGQRIKKILFPSQCPNLMEGDTIVELDGRNVRPIPHTQLVDMLRERPIGYRGKLVVKRGSPKTRSRTPSAAFRYGEPQTNMMDSAAPLPVRSKTPAERQTSRTEEDQNVRNTLQRQPAVTSEWEGMSSAIPASRMRPSSTTLGFATPNYIPLSQYNQKPSDLITVSLIRKPVGFGFRLLGGVESKTPLSVGQIVIGGAAEEDGRLQEGDEIVEIDGHNVEGASHSEAVVLLEAAAQNKHVKLIVRRPSRTDPARRGSLNSAGPSGSYDVLLHRNENDGFGFVLMSSQHKNGSTVGQIQPGSPAARCGRLSVGDRVIAVNGIDILSLSHPDTISLIKDSGLSVRLTIAPPNTAGPVLPMVSATLGRNFTMNGHYESNYGLPPPPPSVYEKHPPPSYLAFDGLSINDRMSMINCGTSQESLLAHLRSSSVMDTYSEEMELLDMEKHLRTEI
The following text describes a protein:
Function:
Transcription coactivator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues (By similarity). Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (By similarity). GIFs are involved in the positive regulation of cell proliferation of lateral organs in a functionally redundant manner.
Sequence:
MQQSPQMIPMVLPSFPPTNNITTEQIQKYLDENKKLIMAILENQNLGKLAECAQYQALLQKNLMYLAAIADAQPQPPAATLTSGAMTPQAMAPNPSSMQPPPSYFMQQHQAVGMAQQIPPGIFPPRGPLQFGSPHQFLDPQQQLHQQAMQGHMGIRPMGLNNNNGLQHQMHHHETALAANNAGPNDASGGGKPDGTNMSQSGADGQGGSAARHGGGDAKTEGK
The following text describes a protein:
Function:
May have antimicrobial activity. A late response immune regulated gene that is negatively regulated by spz during the immune response.
Subcellular Localization:
Secreted.
Sequence:
MFRLLVLAACLAISVHAYSDGAPKAACRDLTPQHGAKLQVTKPPYSISGPSHVRSDQKLTLTLGGDEFLGFMIQARDGQNRVVGQFQVVDSVHSQTLDCSGKDDTITHLSAQKGKPLTGITFDWIPPAGYKGNVKFMATVVQTGFVYWVGRVTKDIDVE
The following text describes a protein:
Function:
Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.
Sequence:
MNENINENIFEEVGDACVKCAKCVPGCTIYRIHKDEATSPRGFLDLMRLNAQNKLQLDTNLKHLLETCFLCTACVEICPFHLPIDTLIEKAREKIAQKHGIAWYKKSYFSLLKNRKKMDRVFSTAHFLAPCVFKQVGDSLEPRAVFKGLFKRFKKSALPPLNQKSFLQKHAEMKLLENPIQKVAIFIGCLSNYHYQQVGESLLYILEKLNIQAIIPKQECCSAPAYFTGDKDTTLFLVKKNIEWFESYLDKVDAIIVPEATCASMLINDYYKVFLGEKDKDLYVKRLEKITPKIYLASVFLEKHTPLKSLLEKIPKGKKETITYHNPCHAKKTLNAHKEVRNLLNLHYEIKEMPDNCCGFGGITMQTQKAGFSLKVGLLRAKEIIDTKAAILSAECGACHMQLNNALKSLDDPNTPPFLHPLELIAKALKSAE
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MGGNIIAKLSTNYCMTHSTIAHSIFSSTIKYPSNQRGKLQNLMSSVSSFHTTNKHTHSSKQNNKRSTMFQIPNNRPIITMFLFLIFIINIITVTSSSSDLRPGFYSKTCPKAETIVRDVMRKALIREPRSVASVMRLQFHDCFVNGCDGSVLLDDTPTMLGEKLALSNINSLRSFEVVDEVKEALEKACPGVVSCADIIIMASRDAVALTGGPDWEVRLGRLDSLTASQEDSDNIMPSPRANASTLIDLFQRFNLTVKDLVALSGSHSIGQGRCFSIMFRLYNQSGSGKPDPALDPAFRLELDKLCPLDVDQNKTGNLDSTPVIFDNQYFKDLVGGRGFLNSDQTLFTYPQTKGLVRFYSRDQSEFFKAFVKGMLKMGDLQSGRPGEVRRNCRVVNDRFAYVLFQHKMQKNVKSI
The following text describes a protein:
Function:
Promotes the eIF4F and eIF4A RNA-dependent ATP-hydrolysis activity with different efficiency depending on mRNAs, thus providing mRNA discrimination during initiation of translation.
Miscellaneous:
MISCELLANEOUS: Over-expression in sns-D leads to programmed cell death (PCD) in the leaves characterized by spontaneous necrotic spots on the rosette leaves under aseptic conditions. Embryo lethal when homozygote.
Subcellular Localization:
Nucleus.
Sequence:
MSKPWGGIGAWADEAERADEEQAAEATATAADSQSFPSLKEAATAKSSKKKKKMTLSEFTKGAYTAPSSAGLTREQMLQLPTGPRQRSEDEMQPGRLGGGFSSYGGGRSSGPPGRMSRDREDSDGSWGGGGGGRRSYGGFDDDQRGSNSRVSDFPQVSRADEDDDWGKGKKSLPSFDQGRQGSRYGGGGGSFGGGGGGGAGSYGGGGAGAGSGGGGGFSKADEVDNWAAGKAKSSTFGSGFRESGPEPDRWARGVLPSGGGVQEERRRLVFEPRKADTEVSETPTAVKTSKPSPFGAARPREQVLAEKGLDWKKLDSDIEAKKGQTSRPSSAQSSRPSSAQSNRSESSALNNVENVVKPRPKVNPFGDAKPREVLLEEQGKDWRKIDSELEHRRVDRPETEGERMLKEEIEELRKKLEKEAAIAPESKESQQESDSNHQNLPDLIREKEKNLDLLIRELDDKVRFRPRAVERPGSSASRGGSYSERPHSRAGSIDESRSVESMERPRSHGTGDNWPRPVDDRRNFQGSKERGFFNNRNFDRSSSAREGW
The following text describes a protein:
Function:
Autophagy receptor that specifically promotes clearance of misfolded MHC class I molecules by targeting them to the lysosome for degradation. Acts as a molecular adapter that specifically recognizes and binds (1) misfolded MHC class I molecules following their ubiquitination, as well as (2) autophagy-related proteins, promoting the recruitment of misfolded MHC class I molecules to autophagy machinery for degradation. Degradation of misfolded MHC class I molecules is essential to prevent accumulation of defective MHC class I complexes at the surface of CD8(+) T-cells and prevent a stronger T-cell-mediated response. In contrast to other members of the family, does not show GTPase activity.
Subcellular Localization:
Lysosome. Cytoplasmic vesicle, autophagosome.
Domain:
The LIR motifs (LC3-interacting region) are required for the interaction with ATG8 family proteins GABARAPL2 and MAP1LC3B/LC3B.
Sequence:
MPPPQGDVTALFLGPPGLGKSALIAALCDKDVETLEAPEGRPDSGVPSLRAAGPGLFLGELSCPPAAPGPWAAEANVLVLVLPGPEGNGEPLAPALGEAALAALARGTPLLAVRNLRPGDSQTAAQARDQTAALLNSAGLGAADLFVLPANCGSSDGCEELERLRAALQSQAEALRRLLPPAQDGFEVLGAAELEAVREAFETGGLEAALSWVRSGLERLGSARLDLAVAGKADVGLVVDMLLGLDPGDPGAAPASVPTAPTPFPAPERPNVVLWTVPLGHTGTATTAAAASHPTHYDALILVTPGAPTEKDWAQVQALLLPDAPLVCVRTDGEGEDPECLGEGKMENPKGESLKNAGGGGLENALSKGREKCSAGSQKAGSGEGPGKAGSEGLQQVVGMKKSGGGDSERAAALSPEDETWEVLEEAPPPVFPLRPGGLPGLCEWLRRALPPAQAGALLLALPPASPSAARTKAAALRAGAWRPALLASLAAAAAPLPGLGWACDVALLRGQLAEWRRGLGLEPTALARRERALGLASGELAARAHFPGPVTRAEVEARLGAWAGEGTAGGAALGALSFLWPAGGAAATGGLGYRAAHGVLLQALDEMRADAEAVLAPPEPAQ
The following text describes a protein:
Function:
Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Reduces the apparent affinity for external K(+), an effect that depends on the presence of external Na(+) and voltage. Increases the apparent affinity for intracellular Na(+).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MTPPTQPRAPTATRTVIFPSPAPTDSSLPPRLPIKRAFSPDSTLWICRSFCAKAQAPPWPRQGAPPPLGKGRGRRRGAGAGAGVAWTGAGSPGTHWLPPPNTRAPPISPDISRSRFQLLQPRLHSLGVQPPLLRPAWRPRLRPPQRDPRLESSSPGRKDAGTAPQEPDPFYYDYDTVQTVGMTLATILFLLGILIILSKKVKCRKADSRSESPTCKSCKSELPSSAPGGGGV
The following text describes a protein:
Function:
Involved in ribosome biogenesis and cell polarity. Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in correct positioning of the mitotic spindle during mitosis (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTEVEERINAWNDGFEELLSYIPAKLYYREHTANQWKQKKSTLEEKKERRKMKFSLDGLVNDADDDSQKSSKWEQSSTMSDDTDVSDRHAESMSQIRGKLASKIQDLREKRKAGDLNQKRQNKRPVENEKDSQKGSGKSKVQKKKHKASPRAGF
The following text describes a protein:
Function:
May act as a carbohydrate transporter.
Sequence:
MGSVTLVVAFAIVAYLTLLTAPTTAFNRYTVGGRNMWNPGVNYSLWNNDTHYYVGDWLVFLYQPNQADVVQVNKTDYEQCRADNPITNYSRGRSYAFRLNHTGDYYFICSKGYCFSGMKLHIHSEKVPPPPPPASADLKSSVVTIRRSVGRFFAIAAAITTAIFS
The following text describes a protein:
Function:
MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDKTSLIGIILAFVALSVGMVLKGVSFSALANPAAILIIIAGTISAVVIAFPTKEIKKVPTLFRVLFKENKQLTIEELIPMFSEWAQLARREGLLALEASIEDVDDAFLKNGLSMAVDGQSAEFIRDIMTEEVEAMEDRHQAGAAIFTQAGTYAPTLGVLGAVIGLIAALSHMDNTDELGHAISAAFVATLLGIFTGYVLWHPFANKLKRKSKQEVKLREVMIEGVLSVLEGQAPKVIEQKLLMYLPAKDRLKFAEQGEAQNGEKKEEEA
The following text describes a protein:
Function:
Catalyzes the reversible reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3-deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH (Ref.4). To a lesser extent, can also reduce 5-keto-D-gluconate and oxidize D-gluconate and 1,2-propanediol. Together with KduI, seems to play a role in the catabolism of hexuronates under osmotic stress conditions, substituting for the regular hexuronate degrading enzymes UxaABC and UxuAB whose expression is repressed in these conditions. In vitro, also exhibits NADH-dependent 20-ketosteroid reductase activity against eukaryotic steroid hormone 11-deoxycorticosterone (11-DOC), which is converted into the product 4-pregnen-20,21-diol-3-one. In addition to 11-DOC, five other C21 steroid compounds (11-deoxycortisol, cortisol, corticosterone, cortisone, and 21-hydroxypregnenolone) are reduced by KduD, but steroids lacking the hydroxyl group at C21 position, such as pregnenolone, testosterone propionate, cortisone acetate, or progesterone, cannot be used as substrate.
Sequence:
MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVEPTETIEQVTALGRRFLSLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDALEFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTASKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRWGLPSDLMGPIVFLASSASDYVNGYTIAVDGGWLAR
The following text describes a protein:
Function:
Transcription factor. Binds to the regulatory elements of genes that contain the sequence motif 5'-TTGTTTCT-3'. Involved in regulating intestinal transcription of vitellogenin vit-2, acting in concert with transcription factors elt-2, mab-3 and daf-16, and also the TGF-beta/Sma/Mab pathway. Functions downstream of the insulin/IGF-1-like signaling (IIS) mediated pathway, in regeneration of axons after injury and in short-term memory, perhaps acting in neurons, and in modulation of longevity, perhaps acting non-neuronally. Plays a role in the modulation of endoplasmic reticulum (ER) homeostasis during chemical and pathogen stress, including exposure to the Gram-negative bacterium P.aeruginosa.
Subcellular Localization:
Nucleus.
Sequence:
MCSTMTATMNQTICEKQNITMDLLRSPIQIPSASDTIKIETPSTISSQPSPIQTPLAAASSDNFERPSLSYKDLIIEAIDRSPEKRLKLNEIYQVIRLLHPYYRHRPDQWGWQNSIRHNLSLHDCFVKLPLKQTSASGVVGHFWTVVPELSDKQTLRRRNRQQPRALAKKSDAGRTLSRDDRGSSGSGETSPSPSQPSISPPNENPMPSVQALNVLELLSGMNDYKGTLFQNNYRTNLIQDNSAVNGLQNLLTTTLMQINPQLGALLSLANLNNLTTNQLQIASPSLSPIKAESQSFLLQ