lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Phosphorylates translation factor eIF2alpha in salivary gland sporozoites during dormancy, which leads to an inhibition of protein translation and accumulation of stalled mRNAs into granules.
Subcellular Localization:
Membrane; Single-pass type III membrane protein.
Sequence:
MLINKRKRRKAYIYNDGYEYINKKIKNKFIFICLIAVGGFSCVYKIKKKEKKEKKGKKKKEKYYYDQKQNCKDKFYALKKIKFHANPKNLKEQILLNLREIKYLNLLKKYTNIVYPHEYWIEIYKPFYKQKKIKSDKKKKNKKKIKKQKLSLFKDTIKIIKKRKKDKLKKKKKIEFFFKNIQYSSDTDDIKITFEDAHPEKVKNNNNIKDIKYIKKKVQKDYKKNNKKNDKNNVNKNNTYNNKYKVVINKIIGKKYIINKIKINRNKKIYIYRHMYGHIYGHMYGHMYDLFNINKNSYYTYNNNNNNNNNDKFKSLKGLKRNNLFINKNQTIPYPSSCYYYSSHTTNKFKSLNEKQFTYVSSFSSHMWCTASRRKTFSYNQKDNYQEIKKLNKYYNYKSSNFLDKQILNKQSMFYQNKINNKKNDHNVVLKTLQTFYDDTYIYNLENVDTQETKQYSNYNNIENVKNVKNVKNVENVKNVENVENIEDMKKKKKNKFVIYNNIYTMQNIKYTSYKSNVFFIDHDVNICNSYSLPNIFTCKTKNKHNAFFFPRHTKFNNRPSKNKKYRLSQRKYYINNYKNKGIKFKLKKIIRKMFQMKNKLRCVTGTYINNYKIGKTIVKNNKKNIKNNNNNKKNNNNNTNKKKYYFYNQHSPCIDIFKKTKRRKKKKKKKKKKKKITFINLLFNNQIKYQTKNCKNKINNIQSRECAHKILSCHHVFILLYYIYKNKTSISELLYEQYINNIKKNFLINKLINLYIPIYNYSEYSFNISFIYYILSNKKRKQFKPTNILSPQVYSYFYYSNVLFGSRYVHQKKKIHRNIHKSKLSNMYAHLSNLDLFLCYRNKHIYKYIKKRQALFNFFFYKRSYITHYEKYFTNKHFIKTQKSQLKHFTRRPTLKMSENNYSSKNYILKKCYMFKIKKKIVKNVNIRRNKNMCMYLSYVIHIIKSHNLCNKINKEFNKQLTNNVCKKKVARQIILDIFYNKTHPRHHIIKYTYNFYKKNICLSGCKKRIFLKIYCFHKGGYVFSRLYGREIKKKKKIERIRNIQVQKQMDYKSRPFINNKRSSKISKQIIYFSLNIILKNYIDYILRKRYFLCSYDHNLIERKWLMYYFTKVVSKYFLNPRKDNNNNNIMFNNNNIMFNNNNIMFHNNNIMFHNNNIMFHNNNIMFHNNNSMFNNNNIMFHNNNIMFHNNNIMFNNNNIMFHNNFIVNNYMDKYKNMFIKSCNDKSIPYQMLANLQNEYYLSKGNNNKMNITTTYLYMKIRKILNKYSKRNEEKKNILKGKYCYNNGNFALLSYINKKHKHNKRYHQIKEKNGNNKETKYKFNLYIRMEYCKSTLENYINTRENMNINRNYEIIQMIILGLYSIHNNNIMHRDLKPSNIFISDNNIVKIGDFGLASYDYTYPKNRKRKKRKRKSSNLSYEYNIRKTNILNLQKNNTPFNIDKYNNNIIRKKKEILFKNCCTKNNIPTKEINSNSSFQYFTKKKKKKKNVHDHHTLGIGTKIYAAPEQLIGNKYTKAVDMFSLGLIIVDLFTITKTNMERMKILCNARHRILPDLLIKNHPQVAKLCQNLLSLDYHLRWTSEELYKKKKNIYIY
The following text describes a protein:
Function:
Sorting receptor involved in the transport of vacuolar enzymes from the Golgi complex to the vacuole.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein.
Sequence:
MPTQLQRPLARLLALALLVLLARAAEDEPPFCAVRNRSTGSYIDLSPLASNVSGTPPNWLVRGWQYGANFTLGVCTSPLGDGPAAYYSDTGRRVSIGRVATTPRYTGKKLTLTYEGGDLCPNRVDRKSSLLYFVCDRDIHTIAQVSLLGVLHNCSYLFEVRSVHACAAARAAGDRSVLGIFAAILLVFAAVELARRCCAAPLRRRFRPDFPADRPRWAPAPTGWAARTRAFFARAAEPRQAIKLASSPPGHPASDMEAQNTLLDSLDVRSSGA
The following text describes a protein:
Function:
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Subcellular Localization:
Secreted.
Sequence:
MCSYLRHRPEGRSSNILESRVTESPTSARTAASARSPMAPTSAFLTALVLLSCNAICSLGCDLPQTHSLAHTRALRLLAQMRRISPFSCLDHRRDFGFPQEALGGNQVQKAQAMALVHEMLQQTFQLFSTEGSAAAWDESLLHQFCTGLDQQLRDLEACVMQEAGLEGTPLLEEDSILAVRKYFHRLTLYLQEKSYSPCAWEIVRAEVMRAFSSSTNLQDRLRRKE
The following text describes a protein:
Function:
Required for normal Golgi function.
Subcellular Localization:
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MEGGDSTISVAGRGASGSAVVAATVQAILQDDCYSEFLNEDFDVKTYTSQSIHQAVIAEQLAKLAQGISQLDKELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRMKSKIVEPYNKIVARTAQLARLQVACDLLRRIIRILYLSKRLQGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGVETQNPTQVGTALQVFHNLGTLKETVTSVVDGYCAALEDSINNALDVKVLTQPSQSAVRGGPGRAAMPTPGSTAGFRASLWTNMEKLMDHICAACGQVQHLQKVLTKKRDPVSHICFIEEIIKDGQPEILYMFWNAVTLALSSHFHSATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQSSQNTQGTFSPSGTPDLCVDLPHMEDDTQDMFRLKRPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGITKTITSELNVAAVDANLTLAVSKNVAKTIQLYAVKSEQLLSTQGDASQVIGPLTEGQKRNVGVVNSLFKLHQSVTKVVASQSSFSATAEQTIMSALKTIHDLMGNAIQPLLTSVADAIEAIIITMHQEDFSGASSSSGKPDVPCSLYMKELQGFIARVMNDYFKHFECLDFVFDNTEAIAQRAIELFIRNASLIRPLGEGGKLRLAADFAQMELAVGPLCRRVSDLGKSYRMLRSFRPLLFQTSEHVADSPAVGDIIPFSIIIQFLFTRAPAELKSPFQRAEWSHARFSQWLDDHPSEKDRLLLLRGALEAYVQSVRSRDGKEFAPVYPIMVQLLQKAMSALQ
The following text describes a protein:
Function:
Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MPYDSVYSEKRPPGTLRTAWRKFYSDAPAMVGLYGCAGLALLCIFGGWIAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFIVTLAATLCGLVLGVVAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPHLSHAMFAVWLALLPRMVRSVYSMVHDELEKEYVIAARLDGATTLNILWFAILPNITAGLVTEITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAITLSVLLVNLLGDGIRRAIIAGVE
The following text describes a protein:
Function:
Plays a role in retention of a subset of membrane proteins in the early Golgi compartments. Facilitates endoplasmic reticulum to Golgi transport of mannosyltransferases MNN2 and MNN5.
Miscellaneous:
MISCELLANEOUS: Present with 1810 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Note=Early Golgi.
Sequence:
MLLELISYAGTVSGFLFLTLSIASGLYYISELVEEHTEPTRRFLTRAIYGIILILILLLLLDGFPFKLTLFSIACYIVYYQNLKSFPFISLTSPTFLLSCVCVVLNHYFWFKYFNDTEVPPQFKFDPNYIPRRRASFAEVASFFGICVWFIPFALFVSLSAGDYVLPTTSEQHMAKKNDDITTNNQPKFRKRAVGLARVVINSVRKYIYSLARVFGYEIEPDFDRLAV
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Subcellular Localization:
Nucleus.
Sequence:
MDANFEDQSKLPELKLDAKQSQGFLSFFKTLPHDPRPIRLFDRRDYYTAHGENATFIAKTYYRTTTALRQLGSGLDGLSSVSVSKNMFETIARDLLLERTDHTLEIYEGSGSSWRLVKSGTPGNLGSFEDVLFANNDMQDTPVVVALLPNFRENGCTVGLGYVDLTKRVLGLAEFLDDSHFTNVESALVALGCKECLLPLESGKTSEIRTLHDALNRCGVMLTERKKAEFKMRDLVQDLSRLVKGSIEPVRDLVSGFEFAAGALGALLSYAELLGDESNYGNYSIQRYNLDSYMRLDSAAMRALNVLESKTDANKNFSLFGLMNRTCTAGMGKRLLHMWLKQPLLDVDEINSRLDLVQAFVEDPALRQDLRQHLKRISDIERLMHNLEKKRAGLQHIVKLYQSSIRLPYIKSALERYDGEFSSLIKERYWDPLELWTDDGHLNKFVALVESAVDLDQLENGEYMISSTYDPALSALKDEQESLEHRIHNLHKETAKDLDLALDKALKLDKGTQFGHVFRITKKEEPKIRKKLTTQFIVLETRKDGVKFTNTKLKKLGDQYQRIVEEYKNCQKELVNRVVQTTATFSEVFWSVAGLLSELDVLLSFSDLASSCPTAYTRPIITPSDEGDIILEGSRHPCVEAQDWVNFIPNDCKLVRGKSWFQIITGPNMGGKSTFIRQVGVNILMAQVGSFVPCDKASISIRDCIFARVGAGDCQLRGVSTFMQEMLETASILKGATDKSLIIIDELGRGTSTYDGFGLAWAICEHLVEVIKAPTLFATHFHELTALAHENSVHEANMKQIVGVANYHVSAHIDSSSHKLTMLYKVEPGACDQSFGIQVAEFANFPESVVSLAREKAAELEDFSATAVIPNDAIEEVGSKRKREYDSDDMSRGSARAHEFLKEFSNLPLETMDLKEALQKVSKMKNDLQKDAVNSHWLQQFF
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MDEEKGLELSLGLACGGSSSNSKTDPDERTSKILNDFKNFLSAVPKSVQRNDAVKPQENFFSNLQQTGNGENVSDDEPRVGDKRKNVFDEMNNQKKQEIDSRNSDLQEKDKMSHISITTDEGSTADNEDVAESEAEGSTSRLASHQEDGSRTPGGSGSSSQAPKELCGKPISSTPFSVQSMNSMNVPYSITIKEPPSVNAPSTPNYSLSGMMQGIASTNGERPRLHATALGSLPMSFGYSPVQLPVLDNKDSPWRMVPLPHSIPSPYAGRSISTSVPMQVLNSSSESVRLDVHPSEEPKGQPQLVAEEGSSSQVEDDAKGRGNSFPSEYPAIRPGIATEMNFGGSGSFPNLPWVSTTSPGPNGRTISGVTYKYNATQIKIVCACHGIHMSPEEFIRHATEEEQSPATTTPNLTSMRSTNPTTTSAKT
The following text describes a protein:
Function:
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
Sequence:
MKVGNALFKLMSELGIRQVFGNPGTTELSFLKHMPKDFNYYLALHDGISVGMAEGYYFATRKPQIVNLHSSPGLTNAMGFIYEALISRIPLIVLVGQQYLYRLIDEPVLYGDFIKISQGVVKSAYEIRSEKDAIKTFIRAYKESITPPYGPVLISLPQDIPDMEVSEGEKVDIPKYFVSGTCDTSAIEFVLDKVKSASSIAIVAGYEVSIFSAHEELVRLAEKLNAPIYTEPYLSIFPIDSSNILFKGPLSRYKASDVVKELEKYDLVLVIGGWLNYVVFPDVDIRLNIVEVTSDFKEASKRKWDTIVCNPKDFLIKLYNMLYKGLNKNIIKRENRDLELQGDFITEVFKEMKGYLDKYTIFAEIPTYRDTLIKIIELKPSSLYITRSGLLGWALSALVGYSINGAKVLAIIGDGSFNYTPQALWSAVKYSTRLKVIVINNEGYASLSRHGVEADWLFPSTSPWKVALAYGFEAKESRDIKNDLKWLFEDDKRKLLEIRLARH
The following text describes a protein:
Function:
Transcription activator. Positively regulates abscisic acid (ABA) response. Confers drought tolerance and sensitivity to ABA.
Subcellular Localization:
Nucleus.
Sequence:
MNMSDLGWDDEDKSVVSAVLGHLASDFLRANSNSNQNLFLVMGTDDTLNKKLSSLVDWPNSENFSWNYAIFWQQTMSRSGQQVLGWGDGCCREPNEEEESKVVRSYNFNNMGAEEETWQDMRKRVLQKLHRLFGGSDEDNYALSLEKVTATEIFFLASMYFFFNHGEGGPGRCYSSGKHVWLSDAVNSESDYCFRSFMAKSAGIRTIVMVPTDAGVLELGSVWSLPENIGLVKSVQALFMRRVTQPVMVTSNTNMTGGIHKLFGQDLSGAHAYPKKLEVRRNLDERFTPQSWEGYNNNKGPTFGYTPQRDDVKVLENVNMVVDNNNYKTQIEFAGSSVAASSNPSTNTQQEKSESCTEKRPVSLLAGAGIVSVVDEKRPRKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRSVVPNISKMDKASLLGDAISYIKELQEKVKIMEDERVGTDKSLSESNTITVEESPEVDIQAMNEEVVVRVISPLDSHPASRIIQAMRNSNVSLMEAKLSLAEDTMFHTFVIKSNNGSDPLTKEKLIAAFYPETSSTQPPLPSSSSQVSGDI
The following text describes a protein:
Function:
Lipolytic acyl hydrolase (LAH).
Domain:
The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
Sequence:
MDESWGTVHPPRYGKQITILSIDGGGIRGIIPATILSFLESELQSLDGKEVSLADYFDVIAGASTGGLITAMITTPGDNNRPLYAAKDITSFYLQHCPKIFPQRRGLLGYACKFVSAITGPRYDGKYLHNHLRTQLGNKRLHQTLTNVIIPTFDMRLFQPTIFSSYQTLVALGEITREELKNNPNFLGMKPMDYRRFLVLSVGTGSTAPNYSAKDAANWGSLCWFYNNGSTPLIETFQEASADMVDIHIAIFFEALNSENSYLPIQDDTLTGDTSSVDIATEKNLKELVKVGKELLQKPVSRVNLETGKYEAVPNERTNEQALISFAKLLFDERKNRIREYSKTVTTKDTLEAVP
The following text describes a protein:
Function:
Component of the spindle assembly checkpoint which is a feedback control that prevents cells with incompletely assembled spindles from leaving mitosis. Component of the mitotic checkpoint complex (MCC) which inhibits the ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) by preventing its activation by slp1/cdc20.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MEPLDAGKNWVHMDVIEQSKENIEPRKAGHSASALAKSSSRNHTEKEVAGLQKERMGHERKIETSESLDDPLQVWIDYIKWTLDNFPQGETKTSGLVTLLERCTREFVRNPLYKDDVRYLRIWMQYVNYIDEPVELFSFLAHHHIGQESSIFYEEYANYFESRGLFQKADEVYQKGKRMKAKPFLRFQQKYQQFTHRWLEFAPQSFSSNTNSVNPLQTTFESTNIQEISQSRTKISKPKFKFSVYSDADGSGKDGQPGTWQTLGTVDQRRKENNISATSWVGEKLPLKSPRKLDPLGKFQVHCDEEVSKE
The following text describes a protein:
Function:
Actin-associated protein that may play a role in modulating actin-based shape.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MVAEEVVVTLSGGAPWGFRLQGGAEHQKPLQVAKVRKRSKACRAGLRETDELLSINDVSCGSLSHAEAMNLIDSGRGTLHLRIKRAPAPYQSVVLVGRAPSPRIDKEYRAALRALSPPLSSKPSGVNRASLMSPTGLEWLTSPPDSEAYYGETDSDADVAAQERQRRQKRRSPSTSPAKIPGQTSPQEEETSGLSGYESTQDVMYPQTQSWPVPDVEGMGTLQKQVMHGVARREVVFQPQQNEWSQQGENSSENSDQSPSGAAEVDSGFQEPPTVPPPLVSPERAKEALMLASHRQMVPMVGPVDNPVDEELTVTYMDKARQAKLHRGESLQDKQVKEARSKCRTIASLLTDAPNPHSKGVLMFKKRRQRAKKYTLTCFGSVDGESNSNTEGETEDESLFPGSESELDEDGFSAAPDPTWDSGYLDVLDKRTSACIVPDREAEISPGLNATSGKGAQLFEQQRKRAEEHVSNLNTFSMPQHQGDSTLTYTPVAPYTPQSTSSLSTSMVNGEPLVVSRTSVVLSSPGQTPMPSLTGALPEQIDSSAASSVHNRTARPFAPGCVSNRAATAPVVFRPSPAKKAGSQSQAVSVATLPAAFSPVVSEGKKAISTSSLYIPARPATYNGPSSLLSPSSVISSPFSPPPSNAPLYSPTYSSTSAPFSPTTSHVTSLSLPSGMAQTYSQPQAMPFSPPHPTVSSQFQPPPPVNVPAQPFSSSFMNAPGFPNVPVHPPTSLNMQPSPSHKVSFNPYISVASTTPETPNAPIAQQYPLSNSTDGISSREQRLSVPAGRTGILQEACRRSTKKPMFSAQEEKKAPSFNPELLSLVQNFDDRSRSGVEAGFESGPEEDFLNLGAEACNFMQAQKNRLPPPVAPKPGHPAPEMPQMRGKGAELFARRQSRMDRYVVDKQPKSPAQPRDPSPTPSLPGNWKYSPNIRAPPPINYNPLLSPSCPLVAQRSTKANDATKVGVKTMHGHNKQGIKALDFVSKQPYQLNPSLFSYGANPQNNTTCQQQQQNGVGITGQFLNPPKQVPIKAGRVYEIKRFSTPTPMSAPTSLTPTVIAPRSATTLGEPMWRSDVTSPPPVAPRPAAPFSPPPPAPTAALPALPKISSAANSGPITQPNQGQAYTPFQTAKQFKSAPELSPLSAGVRSSGSASGLNLRVPRPRFCTSSMGLQPNVWRPGSIHY
The following text describes a protein:
Function:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSVLASMMSSGEDEEQAAADEQERTDLWQQTLQAAVAASSSQDATKKRPAQRKPLRQTNVVERSERSLLCLSLNNPIRKLCISIVEWKPFEFLILFMICANCIALAIYQPYPAQDSDYKNTLLETIEYVFIVVFTIECVLKIVAMGFMFHPSAYLRNAWNILDFIIVVIGLVSTILSKMSIQGFDVKALRAFRVLRPLRLVSGVPSLQVVLNAILRAMIPLLHIALLVLFVILIYAIIGLELFCGKLHSTCIDPATGQLAQKDPTPCGTDTEGSAFKCQPSDSLTNMGVRWECSSNTTWPGPNNGITNFDNFGLAMLTVFQCVSLEGWTDVMYWVNDAVGREWPWIYFVTLVILGSFFVLNLVLGVLSGEFSKEREKARARGLFQKFREKQQLEEDLKGYLDWITQAEDIEPVNEDEQEDEPVAQTVVGEEADEEGEERVEDVRPSKWAARMKRLEKLNRRCRRACRRLVKSQTFYWLVILLVLLNTLVLTSEHYGQSEWLDHFQTMANLFFVILFSMEMLLKMYSLGFTTYTTSQFNRFDCFVVISSILEFVLVYFDLMKPLGVSVLRSARLLRIFKVTKYWTSLRNLVSSLLNSLRSIISLLLLLFLFIVIFALLGMQVFGGKFNFNPQQPKPRANFDTFVQALLTVFQILTGEDWNTVMYHGIESFGGVGTLGVIVCIYYIVLFICGNYILLNVFLAIAVDNLADADSLTNAEKEEEQQEIEGEDEEFEEGEDEGEEHGMDEPEGDEEMTSARPRRMSEVPAASTVKPIPKASSLFILSHTNSFRVFCNMVVNHSYFTNAVLFCILVSSAMLAAEDPLQANSTRNMILNYFDYFFTSVFTVEITLKVIVFGLVFHKGSFCRNAFNLLDILVVAVSLTSFVLRTDAMSVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIMLVTFMLQFMFAIIGVQLFKGTFFLCNDLSKMTEAECRGEYIHYEDGDPTKPVSKKRVWSNNDFNFDNVGDAMISLFVVSTFEGWPQLLYVAIDSNEEDKGPIHNSRQAVALFFIAFIIVIAFFMMNIFVGFVIVTFQNEGEREYENCELDKNQRKCIEFALKAKPHRRYIPRNRLQYRVWWFVTSRAFEYVIFLIIVMNTVSLACKHYPSSRGFEDFLDVFNLIFTGVFAFEAVLKIVALNPKNYISDRWNVFDLLVVVGSFIDITYGKLNPGGTNLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFMKSFQALPYVALLIVLLFFIYAVIGMQFFGKVALDDSTSIHRNNNFHSFPAAILVLFRSATGEAWQDIMLSCSDREDVRCDPMSDDYHKGGLNESRCGNNFAYPYFISFFMLCSFLVINLFVAVIMDNFDYLTRDWSILGPHHLEEFVRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRLACKRLVSMNMPLNSDGTVCFNATLFALVRTNLKIYTEGNIDEANEQLRSAIKRIWKRTHKDLLDEVVPPAGKEDDVTVGKFYATFLIQDYFRRFKKRKEMEAKGVLPAQTPQAMALQAGLRTLHEIGPELKRAISGNLETDFNFDEPEPQHRRPHSLFNNLVHRLSGAGSKSPTEHERIEKGSTLLPFQPRSFSPTHSLAGAEGSPVPSQMHRGAPINQSINLPPVNGSARRLPALPPYANHIHDETDDGPRYRDTGDRAGYDQSSRMVVANRKYADARIVGAARREIEEAYSLGEQEIDLAADSLAPLMQHVGMHDIRDINENSRSALLRPAENSSRQHDSRGGSQEDLLLVTTL
The following text describes a protein:
Function:
Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center.
Sequence:
MEAPQSLIGKLYTSYCDGIHFAKPISSFRTNEVDLVRNVLQILQGFTSTLLYWDELGQRFCVRSGIYVSHLSHTSLYHVLNQFTYAATCLKMVEIRIHKVEKSVPSPPPTLRAFCCSISTWLTWLREGALKEEMKVVNSSSLTTPTLLGLSSSLSSLCAGAEFLFQLVQGAIPQAYDETNSSISATAIAVHILNYLFKKLTEVCLVQGGEEDAYRMILHAFVSSLLPYIEGLDSWLYEGILDDPFEEMFFCANKGIAVDESEFWEKSYLLRSAKLDTGCQADSLLSIKRTNDMGRREPNDVPGLANEKEAKERGLDVCPLFIKEIARDIISAGKSLQLVQHTTMRSSVSASSIQTGGRIAGLSLSEIFCVTLSALIGYGDHISDYFFQEKKIVSLVKSIIGRQKVERSNESFQEMACSDKEWCKFLVDTVAQKGRADLDSCHALGEEVDSFVVKGDKLPLDGNDILSLGFRPENPAITTSQNFLHANRDAWGALNLSREFYLPPLNDEGLREAIFIGSGGSCVATKNTNYTFGFQFGESVRDRLEEDVNFLEELFPFPTLLPPFQEDHHVSEVFPFQENSTLPSRTLNWIGRVEPRNTPLPTVILQECLIFFIKKQADCIGRNILSKLLCEWRLLEELEVLRAIYLLGSGDLLQHLLTVVFNKLDKGESLDDDFELNTTLQESIRYSADATLLSSPDSLIVSVTRNNATSDDDQHGMPVPTSTPRKSRGQNFGIDGLDTLMFTYKVPWPLELIANTEAIKKYNQVMRFLLKVRRAKFVLDKARRWMWKDKSSTSINRKHHWLLEQKLLHFVDAFHQYVMDRVYHSAWGELCDGMAAARSLDEVIEIHEAYLLAIQRQCFAVPEKLWALIASRINSILGLALDFYSVQQTLSSGGAVSAIKARCEMEINRIEKQFDDCIAFLLRILSFKLNVGQFPHLEDLVTRINYNHFYMSHNGSLINAPSSNAVPSKSGKFFSNQRD
The following text describes a protein:
Function:
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIKIILISLALIFVIIGALISALAAIGLLRLEDVYSRAHAAGKASTLGAMSLLFGTFLYFIATQGFVNMQLIVAIIFVLITGPLSSHMIMKAAYNIKTPYTKKTKVDEISEDLKDTKL
The following text describes a protein:
Function:
Involved in triacylglycerol (TAG) biosynthesis. Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA. Incorporates preferentially monounsaturated fatty acids (MUFAs), especially oleic acid (C18:1) and to some extent palmitoleic acid (C16:1), into TAGs accumulating in seeds oil. Can also use, with low efficiency, hexadecanoic acid (C16:0), linoleic acid (C18:2) and linolenic acid (C18:3) as acyl-CoA substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MEISGTVLRQVSYVSGYGTHTRSRGLAPRFGVRMGMGSGFCDEGHLRYYQDTKKVLTPKKKLKLLKGFSKLGLASDPEKLAMFYDLQQNLTSDAGDVLLRELEAARAKEKEVKKKRKQEKKAKLKAAKMNCESSSSSSSESSDSDCGCDQVVDMNTFRAGVGVGVGVGVGVVAPAPVEESPLPKTAPIVEDANAHCVAMELCSKNDIYVSSASNGFKNESAVVTSAPQKRIEVCMGNKCKRSGAAALMQEFEKVVGVEGVAVVACKCMGKCKTAPNVKVQNSVDHNSLAQGLDDSVKIPANPLCIGVGLEDVDAIVARYFWESHTDIGMAGAGAATAT
The following text describes a protein:
Function:
Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MFRGLIYFINMSLSPNWKALQASTPGGGAKGQPGDAKRNRAKAWRAKKSENKKVVGQLDPGLSKAKNVAKSKVIKCQALQIPLRARVHKNDPTRPTLGAILQSDDAGLEEALHAPPQPIEPVLARWKCAPGKFIALDCEFVGVGPNGARSILARVSIVNYYGHVLMDEYVKPIERVTDWRTWVSGVTPAMVANGISFSEAQERVKRLLNGRTLIGHALINDLAVLGLDHPRADIRDTQKPQYFKTVCGCKTPSLKHVMKECVDLNIQQGEHSSVIDAQAAMLLFRCYKKEF
The following text describes a protein:
Function:
May play a role in ribosome biogenesis.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MVHIKNKKQRERVEQSTLFAEAKEKEIQDRLKYGAPVEEKSDDQLFYMDKSGGKNKSQFKDVPLTRAEKILAPNPNVEVLSKDVKQDNKVFNEIKKVEKKFEKIHENKKKEILQIKKITKGQRKQQREKEHKKKFELWGEEPKPAEPVDQENDFVSKNLLENRNLKAKKVNHPALIKKVLSIDLPEPGMSYNPSYNDHQDTLGVAVAKEIIAQDYIDGIDNQLNPEVVKYQDNGIVENIEFEPATNEPTDRITKKEKNKRIRRAEEMKRQKAAQEKKLFNQQIDKVLETLEEVKQEEDIQKEKREKRVEKKKQNTLPRRLGKYKINEIQEPILLTNQLPKSFSSISNDNYNPLKERYHNLQKRHVIEASGPQNKPKKAKLKVYTSNAWNNTTPASIDN
The following text describes a protein:
Function:
Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation.
Sequence:
MTNFLVCSPGFIARIGKRIQFIAGSSTPPLLHTMVLEESLSCEEAASLAAVAMAKPLRRSYVHGASECQLLFETVGDLLRSASEKVPDREFVIFKRDGVRKTYKEVLNDAEDLASGLLHLGVEKGDRIGIWGPNTYEWVVTQFAAALGGMILVNINPSYQSEELKFAIDKVGIKVLIAPPGFKKSNYYQSAIIPEVVTKSEGRSDISTHAFPTFRHLIIFDREDKSYQGAWRYSDVIKMGNESDRLKLSQIEREIQPDDPCNIQYTSGTTGEPKGATLSHHNITNNAFFVGYRAGYQEQAIDSEGCTALYGTPTMFIDMLNHPDFHKYNMTTIRSGFIAGAPCPITLCQRLVKEMNMHDLQVCYGTTETSPVSFMSIRNDPPEQRIKSVGHIMDHLEAAIIDKFGKMVPRGEKGEVVVRGYSVMRCYWNSEEQTRKEITADRWYHTGDIGVMHENGTVSIVGRSFMGTAFAPVKSDIAGNVRTRWLKDPIGQDTLQKLIASDLKDNGGKLGIATEGLLWLKRGQEFMLLMLIFMVRDYRKDKASTESLVSYSKWPTMADPVVEDQSSSSQDEVLQIKTLTKKQIQVLYRLLILIVDNFGGGRKDLFGCEGGRREGTSTAEGRKEEREGGGWKERGVEECEEKRLEGPMGGEEKKDMIVRGGENIYPTEVENFLDRYQKVADVHIVGVPDERFGEVVCAWIRLKDEYEGRCTEHEIREFCAGKIAHFKVPRYILFKKEKDFPMTATGKVKKFEIREISKIELARRNENQLLLRGNFVVPLRIGAF
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MASLRGVSRSARALQPFSAQFAVRRCASTQTGAGAAAATPKSNIPDLAELETRSALDAPIPSEEDKKEFRPWKRAADRKARLPSSRYQYHPPKYNRGPLHPIQSPPSSDPIARDFVPGPFNMPRLKETFRTVMASDLMTLAYIHTPPGTPKKEPTERLRAWEGDSPYFANRARRAPRGAPELPIRERDISFRNIPEIKEITVSTFVPLGLKNPDLLIVARAVLLAMTGTMPEMTRSKNNVVQWQLQANKPAGCKTTIYGNAAWEFMDRLIHLVLPRIKDWKGVPASTGDGSGNVQFGLNPEDVQLFPEVECNYDMYPAKMIPGCHIAIKTTATSDRQAKLLLQSLGVPFYSN
The following text describes a protein:
Function:
BREX systems (bacteriophage exclusion) provide immunity against bacteriophage. Part of a type 2 BREX system (Probable). Previously called the phage growth limitation (Pgl) system, it confers protection against bacteriophage phiC31. The bacteria allows one cycle of phage infection, but subsequent cycles are impaired, protecting the original bacterial colony (Probable). The system undergoes high rates (10(-3) to 10(-4)) of phase reversion, i.e. loss and regain of phiC31 resistance. When the pglW-pglX-pglY-pglZ genes are transformed into a susceptible S.lividans (strain 1326) they confer resistance to infection by phage phiC31 and phiBT1; all 4 genes are necessary. The proteins has kinase domains and might bind DNA (Probable); Autophosphorylates when synthesized in vitro, cannot be expressed in E.coli.
Domain:
The first protein kinase domain is predicted to be catalytically inactive.
Sequence:
MREGRWVTVTESEFEHERRGLEAIRQKLPDGDPWRAWSNFTFTANTGHVREVDLLVVAPGGLCMVELKDWHGSVTSENGTWVQTTPGGRRRTHGNPLHLVNRKAKELAGLLAQPGAKRVWVAEAVCFTDNGLRVRLPAHDQNGVYTVDELVDMLKQAPSDERRRVTAIGSREVAAALKNIGIRKSDAQYKVGPYELERKSFDSGPTWADYLARHSDLPEAARVRIYLSERGSDASLRQSVENAARREAAVLGRFKHPGAVQLKQYFPSGHAAGPALIFDYHPHTQKLDEYLVQYGEKLDILGRMALVRQLAETVRSAHASRIHHRALAARSVLVVPRSRGGKGRAVGEEAAWLTPQLQISDWQIATQRSGDSSQGQGMTRFAPTALSAMHLADDADAYLAPELTALNPDPVYLDVYGLGVLTYLLVTGKAPAASQAELLARLEAGEGLRPSSLVDGLSEDVDELVQAATAYRPGQRLSSVDEFLELLEVVEDSLTAPAAALDGPAEDETGASADKDPLEVVAGDLLAGRWEVRRRLGTGSTSRAFLVRDLEAETRRTRPLAVLKVALSDSRGEILVREAEAMRRLRPHSGIIRLAEPEPLHIGGRTVLALEYVGDERDDDGPGAEGATRPRRREETVARQLREHGRLPVDQLEAYGDYLFGAVDFLEGEGIWHRDIKPDNIAVRIRPNRTRELVLIDFSLAGYPAKNTDAGTDGYLDPFVDVITRGSYDSHAERYAVAVTLHQMASGELPKWGDGSVLPRMTDPKEWPYPTIAAEAFDPAVRDGLVAFFQKALHRDAGKRFPELKPMRDAWRKVFLDASQTVPSSHRTRPAAPADGAAPAEGAAAGIADAEPETAEQQRDRLAAEVTRDTPLTVSGLTPAAQSFLYGLGITTVGELLDYSRRKLVNAPGLGAKTRNEVQQRQREWGERLREAPVSPLTPKGRAEAKEELEQLTAAESALVGQLATGESAGALSARTLRSVSLDTLATVLVPAVNNNGSNRNKAEMVRLLLRLPDEHGVLPGIGVWPKQKDVADALGLSHGRIPQMLKDERKRWKAEPAVQALRDEIIELLASMGRVASAVEIADALAVRRGTHLAGREQRRAMALAAVRAVVEVEQLVPQEVEFQHQPNRKATDESLGAGLLALDVREDDAPDTPTAPGLLDYATRLGKTADRLARLDTLPTAATVLAELGALTVPPGAVDWDERRMVELAAAASVNAAATPRLEIYPRDLSLVRALRLTQAGLVRWIPGVPEGRQPGLTGEDVHERVRARFPELVVPDGRGGTAHELPTAGPLTKALRDAGFELSLSMREDTGTLRYLPTRVDEASSYLTTGAWRQSTRTGTVTRYADDPQLAGAVRAEERLLASAHRDGYRVLTVRQQLVRDAVRELGAERLGGQAVSVTELFLEALHGQVTPGTKPTWETLLKADAAEPGSKGAVRFAEYARTAWGSVEPRIAELLGDGGGGAGPVLLTEAGVFARYDAMGVLDRLASAARRGGRGLWLLVPQSDPSREPRLGQVAVPYQAGLGEWIQLPDTWVGNRHRGSGEVVASGVEGDAK
The following text describes a protein:
Function:
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
Sequence:
MTIQQAIQHAITQLRTISPTARLDAELLLAHILGWSRAKVVAERDHVLTPEQEMAFNALIERRANREPVAYLIGHREFFGLDLFVDRRVLIPRPETELLVELTLKEAQRFNHTPLIIADIGTGSGAIAIALAMHLPHALIYGVDISPDALAVAAINVTRYRLDDRIRLLEGDLCTPLPAPVDILVSNPPYTILTEIDEGVYRHEPHLALDGGSDGLDCYRRLIAAAPTYLKPNGAILLEIGSTQAASVVHLLRQALPMAETGIERDLAGHDRIVWARNRYVIH
The following text describes a protein:
Function:
In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.
Subcellular Localization:
Cytoplasm.
Domain:
It contains an N-terminal DNA-binding domain and a metal-binding domain.
Sequence:
MSRRAGTPTAKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVELISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLATMGLIEMIPWRGVFLTAEGEKLAQESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK
The following text describes a protein:
Function:
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
Sequence:
MARSTPSLNALRAFEAAARLRSMSAAANELSVTHGAISRHIRALEETLGVTLLTRGPLSTDPTPDGLRLAEGLAAAFTAIDTAIEQVKPGPLTLSCSASIMMYWLIPRIADFHRQHPGVQLQFNMNYGQFDAVRDRIGIAIRNTMVEPPADVVVKELGRAERIGLVCSPEYLRDTGIKRFADVAAAHRLAPATRPNAWNEWAAAVEYEGATLTTHDSYDHFYLMIQAAICGLGIAPVPQMLVLDDLRSGKLVAPFGFVDGPHKLVLWLAPHVRDRADTLALRTWLADQLARTHDEGEVLAPPHS
The following text describes a protein:
Function:
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins.
Sequence:
MDEACSSRRKRGGRPKSKYWSEAEKLEGKNMWKCNHCKHEFAGGATRIEEHITGKGNNITKCPKYGAHEEDEINLGDQIVEHDSAAFKKAYPKGDPDAVCIKKSDIELLQPEKCLNDTIIDFYINYLKNKLPSDKQDRFHFFNCFFFAKLAGLSRNDTSIACDGKAAFQRVSTWGRKVNLFKTDYIFIPINYSLHWSLIVICHPAEVMTCYRDEETKGSPKEACILHMDSRKGIHVHLQNVFQSYLCEEWKERHNNVRDDVSPKFLDLPFVPLELPQQQNAYDCGIFLLHYVEHFLEQAPINFNRSTKFSVPPPDASLKRSHIQKLLIAAEGDSKMIVGGSVNPQNNTQFSAALLGGDVEDHAVNGGSNGDDALTINNLLSDLAREEDYFDKELQWREFQAIKRKRQDDDWSDKLKDLKKRVIDVKNSLHQSGSTNELPKPSELHAKFIYLLIEKLWELRDENVKKMWDLLEDEEVFIIGIDGMGGVGKTFMATHFKNEIKRKGTFKDVFWVTVSHDFTIFKLQHHIAETMQVKLYGDEMTRATILTSELEKREKTLLILDDVWEYIDLQKVGIPLKVNGIKLIITTRLKHVWLQMDCLPNNTITIFPFDELEEEAWELFLLKLGHRGTPARLPPHVLEIARSVVMKCDGLPLGISAMARTMKGKNEIHWWRHALNKLDRLEMGEEVLSVLKRSYDNLIEKDIQKCFLQSALFPNHIFKEEWVMMLVESGLLDGKRSLEETFDEGRVIMDKLINHSLLLGCLMLRMNGLVRKMACHILNDNHTYLIKCNEKLRKMPQMREWTADLEAVSLAGNEIEEIAEGTSPNCPRLSTFILSRNSISHIPKCFFRRMNALTQLDLSFNLRLTSLPKSLSKLRSLTSLVLRQCSKLKDIPPLGDLQALSRLDISGCDSLLRVPEGLQNLKKLQCLNLSRDLYLSLLPGCALPGLSNMQYLDLRGSSGIKVEDVKGMTMLECFAVSFLDQDYYNRYVQEIQDTGYGPQIYFIYFGKFDDYTLGFPENPIYLCLEFKRRRVCFGDCDELPYLLPRDLTELLVSGNDQWECLCAPLSSNGPLSLKDINIKHCTKLKSLFCVSCSLCTNIQNLKSLKLDNLGSLSVLCKEDVAGLTQSLSRSGVFSHLKELSIEKCHQIEKLLTPGLVPQLQNLASISVEDCESIKEIFAGDSSDNIALPNLTKLQLRYLPELQTVCKGILLCNSEYIFYIKDCPNYETPRIGGRV