lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
Sequence:
MRSDTLMTKNTFTFEEIFEQNERRIHYHLHKLNIRDPHQEFYQEGIIAMWNAYENYQPDKGPLSTYFNFTIHHRLIDLIRKDSRRLEMEELAPKEEDAAFESEVYHKASAPVSPGINPAEHITDDAELWQRVKGLLTEKQWKWVQYYIIEDMSLKEIAAQEGVSIEAVKSWAKEAKKRLRNVDFGKVLVEGNILRIWLV
The following text describes a protein:
Function:
Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function redundantly. Both proteins are integral components of the adenylyl cyclase activation pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSSDSSVNTTSSSFGNISISSPNHSSSTPPLNNGNGNNVSASETELKKHVLYSLQCLDEKTLTLKVKLDHLNKLVELKKSIPDLNKLGISPTQLYKSVRPFIALPPKTIRTAGLRVMRYYLSNSNNVKELLDLKVQYFITRSLERDKHSEPERIQALKIIRTIMEIDCSLMPHCFVKGLVSIAENQEDNFCRVCLECLTEISIRNPQISSHCGGIRTVFDAVLDPFYQGIQESLLICILYLLSDKDTRIYIRPKSDLEIILAPLTNSFNIGVKLKGASKEKEKEKEKEDEVAMKKWTASSKAVLTLIKSWIGIISLNSDDQGLKSVVDTLRMPQIELQEKALDSIFEIFRVQLPKSIQETFGPQKATQTFNFGSETLQDLPSRTRSLRHNLLNNYLSVLLIAFIDNGLIEGLVYLGNYVANRDGMSEQEKECSKNISLKSTVLLAELLHMSNALLPPSQCAKLQTLPSLVNSAISFRLDPRLRSSSNTMVTNLHSYSHNKSSTTLMDSTLAIGLTGANKWRRIKGQDRRLDKVDDVKMKMEWHMDDNQFQQKIKDTQVLVTKDYQKWSWELMFELLEGPLNNPQHLSNTLKTKFIKRILSFLRPNKKLFSTMAWTTENLKYVRTACVALEVLISHEIGFDFLKDNKTIIQIADMLKVELDYNIKPPPSSSSSSENKKDNVRLLNPEKVLKTMSREYFTMLGTLSSNLLGLEILARNNIFDYIKPLAELPGRDDLSHLIMTSLDYNVNGASRTILQKILTSSSRVVRYLATKYLRFLLRSGVQDFSNWGVELLVQQLNDVDAKVSALSLNVLDEACDDPSCLEVLIDLKPNLLKLGKPGKSLLLRFLSSPKGLENLLQNNGFVEQEEQLWITSENATYVNAIESAVSESLSPSVWRFKEAPDGSSTSGVYLPPHFFGELAKTEKGCQLIRKSNNYQRFLKIIQDPTAKQLDKRASLIAIGHIGSSVDGYSFVKESDTIKLLIGIAEKSQCLALRSTCFYALGMISCIEEAQPIFNSFGWESPSDLNSRILLPKDLKNSTFLSVPQYQYQGSWADHSFETLPSNHFSDPIKNEIISFVGNLSSHITAEGASKNLKRLKIKYPDHFATSEILNAVFILLNTFKYRLGARRFIYDLFDVAIFSSDPYHDLN
The following text describes a protein:
Function:
Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
Subcellular Localization:
Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane through a docking factor (PEX13).
Sequence:
MSFMRGGSECSTGRNPLSQFTKHTAEDRSLQHDRVAGPSGGRVGGMRSNTGEMSQQDREMMARFGAAGPEQSSFNYEQMRHELHNMGAQGGQIPQVPSQQGAANGGQWARDFGGQQTAPGAAPQDAKNWNAEFQRGGSPAEAMQQQGPGPMQGGMGMGGMPMYGMARPMYSGMSANMAPQFQPQQANARVVELDEQNWEEQFKQMDSAVGKGKEVEEQTAETATATETVTETETTTEDKPMDIKNMDFENIWKNLQVNVLDNMDEWLEETNSPAWERDFHEYTHNRPEFADYQFEENNQFMEHPDPFKIGVELMETGGRLSEAALAFEAAVQKNTEHAEAWGRLGACQAQNEKEDPAIRALERCIKLEPGNLSALMNLSVSYTNEGYENAAYATLERWLATKYPEVVDQARNQEPRLGNEDKFQLHSRVTELFIRAAQLSPDGANIDADVQVGLGVLFYGNEEYDKAIDCFNAAIAVRPDDALLWNRLGATLANSHRSEEAIDAYYKALELRPSFVRARYNLGVSCINIGCYKEAAQYLLGALSMHKVEGVQDDVLANQSTNLYDTLKRVFLGMDRRDLVAKVGNGMDVNQFRNEFEF
The following text describes a protein:
Function:
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix. Zona pellucida. Cell membrane; Single-pass type I membrane protein.
Domain:
The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
Sequence:
MEFLQGVLVLAVFAVFDPTNAQGSLNNVQSPRGFNMNLRGVPAPPGAVFSPDVMVAFNNLDSGKPVQAPLDLQEKLMLQAPEPFTWMFPIVTEAQREFATNFQLKQPASPGSTVTIQCGPDRVHVEVKQDLFSNGELIQPVGLTMGRRPVVGQDPNSGVLIFDYPIQEPDSVVMMTEDELVYTYTGTYTPEPFPGTPIIRTDGAIVGVQCHYQGLHNVSINALMPAWTPYASAEFGEDILVFSLDLMTDDLSYQRPSNVYFLGSMINIEASVMQYNHVPLRVYVDRCVATPVPDPEALPRYSFIENHGCFVDAKTTGSSSHFLPIVQEDKLRFQLEAFMFQDTPSPFIYITCIVRATVAARHSDHLHKSCSFANGWFANDGHHRACNCCDSTCGHGGVEGQLTGDGFRGIQWEGKALVGPVEVKDIQRKLI
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSAEVAAPQAAGEEMEALCSELLLPSPGAVGAAGAVGSPTATAGAAPLPVSQELVLAEASSPGEGAAAEGSNVEIFIEAVAGNVTLSNAANGTEVLVKVVELYFCERCGQSFPEASLLSQHECLLLPPPEHLQLPEVLPAPTSKGQNESEGSEPPLVGVSEGSALQCLLCPICQEAFAQPGELKEHFKTHRGPQGALPCPEKGCCFATEDRKQLRSHLRLLHGASPVSCTYRACPLLFPSRPAMEQHHRTHFPFHCGHCDFVTANAKLFWQHRKGHVAETSVMSSIPSSAPLKQLCILPSEGQKEAENCHADWEATSEETRPANPSGIGEGSLEELKASAGEEDSESDEDDSLEEDGESPCEGEAKENRKVADKAKVTWAQHFKGDVAEGSEYVYKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCHKYFTSKSKLKIHMMRETGEKVHRCPLCHYSSVEKNALNRHMASMHEDISNFYSDVYSCPVCKEKFRLSQALKEHLKTHKAEPKRLSCFQGGCDYCVEDRKEFVRHLKDSHGIKAVECKYHACSLLFGTAEAMEAHRKTHYAFHCQQCDFICSNKHVFRKHKKQGHPGSEQLQCSFCPYATFNPVEYHDHVGKMHANEKIHKCTECAFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSSDKNFMCTECGYITKWKHYLNVHMRKHTGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLICEVCGFACKRKYELQKHMQAKHSQNYQVPIFQCQYCAYQTKYKQALLNHENCKHTKQKEFRCALCSYCTFSNTSLFFHKRKIHGYVPGDKDWLENYASKELEISSSESVFGYELGAALRVDASSPFSSKEQWAKVKPSQPESQGEEGCQQAFMVPLLGQDAAPPEGSSKAQTAVGKGEQSCTVDDSMQSDTAAGSAELITSEDVAESCTLHLETVNVSSDPILEHLTGDACMAQPESMEMLSCKEPPAAYEMLGSQDDLGLEDNDNELEDIPDYKEEEADVRKDEMLRLEDSAAAGASQENDTIGEATGHLERSCSDHSKLDAGPEMRETSQREPPEAWLSVLKTAEQSHPSIPVDAATSTDDTRNSSESVLKALRKQDKEQAETLVLEGRVQMLVVQSESQIFKCEKCSYITRKEKSMSLHSKASCQSHRTPLVCCECGASFKQQRGLNTHLLKKCPVLLKKNKVLKPAVVEAAGSHRPTGQLGDNGTETAESDRGGMEEPGHPESPWEAKMMPDKMQESDGPFAGEQVSGCPSPVKSLSGDSAEVAEEPSQQGDGAETSGMERPLQAGKPSEKYRLEGGKLHCNACSFVCSRVSTITSHVEDGCRSLEQFWCSLCPEAFRSQRALKNHCAEKHLLHPEEDRPHGTQLPGGDPASAEMGQPADPVLDAAPLKAALPKQRRFSCPTCPFTCHQERAMKTHKKRGCVALGEFRCASCPFTSKAAKALRLHRKLHRKHYSKRPQLQCRQCEFTCKQARCLRQHVRIKHEGVKPHKCLYCEFSTTRRYRLEAHQSLHTGVGRIACGICSQTFGTNSKLRIHRLRVHEKTPTHFCPLCDYSSYLQNDITRHVNSCHRGELNFGCSRCEARFSSETALKQHVLRRHEEKVSYGCPQCGFVCHSEATLKCHVQKQHPHLECGTCKESFPSRDALEEHKKQHFSHRCELCSFAAKERQQLVRHYVESHEPATPQDKPLRCPFCDFACRHQLVFDQHMKGHGGTCIYKCSDCEYTTKNRQKITWHIRIHTGEKPYKCHLCKYTCADPSRLKYHMRIHKEERKYLCPDCGYKCKWVNQLKYHMTKHTGLKPYRCDECEYRTNRADALRVHQETRHRDARSFICEQCGKAFKTRFLLKTHLKKHSEEKPYVCNACGRAFRWAAGLRHHYLTHTNEHPFFCRYCPYKAKQKFQVIKHIQRHHPERGAGDPSQGVGKDPSTPIVRLHAVQRESPAMGPPAPQQEGECLPEKESISQ
The following text describes a protein:
Function:
Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
Subcellular Localization:
Cytoplasm.
Sequence:
MPFVELDTNLPAGRVPAGLEKRLCAATAAILSKPEDRVNVTLRPGLAMAVNGSTDPCAQLIISSIGVVGTAEENRGHSARFFEFLTKEMGLGQDRIIIRFFPLEPWQIGKKGTVMTFL
The following text describes a protein:
Function:
Involved in a signaling pathway that modulates root auxin transport and auxin gradients. Acts partially by positively regulating the auxin carrier PIN2 and AUX1. Acts, together with GB1 as positive regulator of meristem initiation and branching. GB1 and NDL3 positively regulate basipetal inflorescence auxin transport and modulate MAX2 expression in shoots, which regulates organ and lateral meristem formation by the establishment and maintenance of auxin gradients.
Subcellular Localization:
Cytoplasm.
Sequence:
MVGLNNAVSLDIEEICNGGKEHHVKTCHGSVSVVVYGDQEKPALITYPDVALNYMSCFQGLFLCPEAVSLLLHNFCIYHISPPGHEFGAAPVCSNDPSPSVEDLADQILEVLNFFSLEAVMCMGITAGAYILSLFAIKHKERVLGLILISPLCKAPSWSEWFYYKVVSNLLYYYGMSGLLKDIFLQRYFSKEARGSSEVPERDVVHECRRLLGERHGSSLMRFLEAVNRRHDLTDGLKSLKCRTLIFVGDQSPFHSETLHMVTALDRKYSALVEVQACGSMVTEEQPHAMLIPMEFFFMGFGLYRPGRVSDSPRSPLSPSCISPELLSPESLGLKLKPIKTRVPTKC
The following text describes a protein:
Function:
Might be involved in the translocation of teichuronic acid repeating units from the inner to the outer surface of the membrane.
Miscellaneous:
MISCELLANEOUS: The nature of the anionic polymer present in the cell wall of B.subtilis depends on phosphate availability. Under phosphate-replete growth conditions teichoic acids are present, whereas under phosphate-depleted conditions, at least part of the wall teichoic acid is replaced with teichuronic acid, a non-phosphate containing anionic polymer. The synthesis of teichuronic acid is accompanied by degradation of teichoic acid and reutilization of liberated phosphate for other cellular processes such as nucleic acid synthesis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MPSITKQIMSGAKWTSISTMCITIIQIVQFALLGNMMTLTEFGLVGMITTVTVFAQIVLDMGFGAALIQRDDATERQLSTLYWLNIMTGVLLFVLLYVSSPVIAGFYQREELVFLVRILAIMFLIAPIGQQYQYMLQKQLHFNTLSKIEIFSNVLSFGYLAIAVFMMDAILAYVISQVLLQSSKGILYWAVYRKKWHPAFVFDLRGMKDFFSFGAFQLSSRLVNRLGANIDMILIGRFIGAEALGIYNLAYQIVTIPVLKINPIVTRVAFPIFAKNKYENSVIREGFLNMTKMLALVSFPLLIGLVSVSDAFITAVFGEKWLAAVPILNVLAIVGILRVLMNPNGSVLLAKGRADLAFYWDSGVLLLYGLSLFAAVQTGSLLTVAWVYAIISVVNFLIGRWLLAYVIKLNLSAYFQSIMKPFLITAAMGIIAFGVSLSTEHFSMQAEMRLAISVAAGALCYLFLLVKAYPQTKSKLLRKGRLS
The following text describes a protein:
Function:
Required for normal levels of gene conversion events during meiosis.
Miscellaneous:
MISCELLANEOUS: Present with 1820 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSEEEAHKTVEVDDVGVQLDEGDEEDLLEYDDELVEEQPSDARIRNVAETLMKSELPKVTVEYKDTTFLLFTSDDKNESNNPIICENAALYQRPMGEFMESIRKFMGNRFGRLAFATKELVLQLKSLDLTLFEDNVYNNHISFSDVYTIFKILKERSESNFETDIPTHLAIELSTRPRFVSRYNALVELTESSATLKNIKPFSNDETHPLIVDDNDQYTHQNTSEVIVMDIDDDVGEDSED
The following text describes a protein:
Function:
Peptide which plays a role in the humoral immune response to a subset of filamentous fungi, including F.oxysporum and F.verticillioides.
Miscellaneous:
MISCELLANEOUS: 'Daisho' is the Japanese term for a matched pair of samurai swords, one short and one long, and refers to the role of the two Daisho peptides (Dso1 and Dso2) in defense against fungal infection.
Subcellular Localization:
Secreted.
Sequence:
MKFFQAAALLLAMFAALANAEPVPQPGTVLIQTDNTQYIRTG
The following text describes a protein:
Function:
Has both L-asparaginase and beta-aspartyl peptidase activity. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.
Sequence:
MGGYKILKKGGNVVDAVEEAVRILEEDVNFNAGYGSSLNSEGEIEMDACIMVGSNLTSGGVTVVKNVAHPISLARLVMEKSPHFLLAGEGAKKFAKENNVPLIPLASLMAEHTKEELEEYRKNQRKRELEIGGCGGVGAIAVDAQGRVAAASSTGGRLARAPGRCSDSAIVGAGLYADNDVGAAVVTGTGESIARYVLAHEIINLMSRGFDAGVATRNAVKGITERFHQPTGAITVSKNGQVGISFTTDKMAWAYQVRDDVHYGLDDYDHFSEKIKL
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. C31 is involved in the formation of the initiation complex.
Miscellaneous:
MISCELLANEOUS: The acidic domain is essential for its function.
Subcellular Localization:
Nucleus.
Sequence:
MSSYRGGSRGGGSNYMSNLPFGLGYGDVGKNHITEFPSIPLPINGPITNKERSLAVKYINFGKTVKDGPFYTGSMSLIIDQQENSKSGKRKPNIILDEDDTNDGIERYSDKYLKKRKIGISIDDHPYNLNLFPNELYNVMGINKKKLLAISKFNNADDVFTGTGLQDENIGLSMLAKLKELAEDVDDASTGDGAAKGSKTGEGEDDDLADDDFEEDEDEEDDDDYNAEKYFNNGDDDDYGDEEDPNEEAAF
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSSTNTTPKPGNPIVYLDLAFGSSPASRPGSNRIVLELYADRVPRTAENFRVLCTNTSKLASTGQPLSFRNSIFHRVIPKFMIQGGDFTRADGTGGESIYGEKFQDEDLTGKHDVPFLLSMANAGANTNGSQFFITTVPTPHLDGKHVVFGRVLKGKGVVRRVESVETVASDRPKEDVKIVDCGELTGDEVSNQTYGIEQDDTGDQYEDFPEDQDDKLESDVSATYHIGLALKNMANTQFSKANFDIALEKYSKALRYLQLHPILPEDTPADLAANYTTLKTSIQLNACLCALKTTPAQPRVAISNATAVISNLTSNKAPSTEQADKNKYHSDLAKAFYRRASAYVAQKDDERAEADLKHALENAPEDAGVKRELQALARRKEAKLKGMRAAYSKMFS
The following text describes a protein:
Function:
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDRGLSTGTNQSGAGLRERAVTSQADLNVITENPTVTNASNGKDKAGKTFGRTPDGTVFTVPQTHDMVSQLLSPSEPKNLSDLVVLTILAGHIFLLWILPSGAKIPVFAVIYLFWRSCYNAGIGWLLHNQSHHKTLVRWAEKSQIFVNPATGKNPYPQLYHLIKRELEIKISKDYSFEEAPLEYNTWLVFRRLVDLILMCDFASYCLFAIACSRHPANESVLMTVIRWTSGIALVLFNLWVKLDAHRVVKDYAWYWGDFFYLIDQELTFDGVFEMAPHPMYSVGYAGYYGISLMAASYKVLFISIIAHAAQFAFLVLVENPHIDKTYNPPPPRKRTITEHDAASQRSQSPDTPNAPSVSEENVPNATTFSSPPPAVHNLLGFHNLDLHRITDTSSILVQFLMFSLTVLTPSTPWYQFLFVANAAIWRLWYSVGIGYLLNRQSNCKSWTRHFVKYGETPHEAWNQWKGTYHLSMVMCYASFISAVWKMYTLPSNWGYGLAILRHVLGAGLISLQIWTSVSIYESLGEFGWFYGDFFFDESPKLTYNGIYRFLNNPERVLGLAGVWGAVLITASGTVAFLAFLSHILSLGFIQFVERPHMQKLYGRSLRQDAGLVKSLKRSLPPSLRQLHGSVDKIFDESYEFIEEIIDTARPKLAAGVNTFVRDTTALFQKYPARVTISRIDADLAGYDLRDYSLTVEASQLPLDEGDLSKEGDNARTPLDRRGDLENLVFPYGTPVKVKWTAPLNHSKKDWIGLYKVTDNTSREVTRVSSQGRWVAVNEGFYDNLTCERGILISDVVVSTSQGDNGEKHDIATGEVVFSGDKLFWTQGVFEFRYHHNGKHNVMAISRPFEVRIPRFEEEDHFDMSQTAVETSLLPVIQNCFDRDPEIAPETPEEQYGSLVERDGKFAKRVVFAVHQMFGVEFAPEVVRSDGNVRNLAWRICNAKRVLAPYSMSRDGATTPTESKE
The following text describes a protein:
Function:
Functions as a receptor binding protein (RBP) and probably mediates the attachment to the host capsular exopolysaccharides (Probable). Displays a depolymerase activity that specifically degrades some K47-type polysaccharides of Klebsiella pneumoniae capsule, which allows the phage to reach the host cell membrane and bind the entry receptor.
Subcellular Localization:
Virion. Note=Tail appendage. Depolymerase 1 is connected to the phage tail via an N-terminal anchor domain, while depolymerase 2 is attached to depolymerase 1.
Sequence:
MLNNLNQPKGSTIGVLKDGRTIQQAIDGLENPVHYVKDVSITPSALLAVAVEAARLGRTVEFGPGHYTNQGQPFEVDFPLNLDVPVGTFLDFPIIIRGKTVKTVRSVATNLTAAQCPAGTTVIAGDFSAFPVGSVVGVKLGDNTNGSASYNNEAGWDFTTVAAASNTSITLSTGLRWAFDKPEVFTPEYAVRYSGQLSRSSYFIPGDYTSGLNVGDIIRVENIDGTDGVHGNKEYFEMLKVSSIDSSGITVETRLRYTHVNPWIVKTGLVKGSSVTGGGRLKRLEVRGVDTPKVNNVDVDRLIVGLCYNIDVGEITSRGVGEPSSVNFTFCFGRGFLYNVRASGSVSTTDNSALKLMSCPGLIINNCSPHNSTSTGSQGDYGFYVDAYYSPYWCWNDGMSINGIVTETPRSAVTRALWLFGLRGCSVSNLSGAQVFLQGCAKSVFSNIVTPDNLLELRDLSGCIVSGMANNALVLGCWNSTFDLTLFGIGSGSNLNIALRAGAGVTHPETGVPTTLGKNNTFNVKSFSQSSLAVTLSIAQQERPIFGAGCVDVDSANKSVALGSNVIVPTMLPLALTKGIDSGSGWVGGRTKGGIWFDGNYRDAAVRWNGQYVWVADNGSLKAAPTKPDSDSPSNGVVIGP
The following text describes a protein:
Function:
Participates in homotypic or heterotypic interactions in the eye during pattern formation to prevent extra cells from joining the precluster and differentiating as photoreceptor cells.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MLKSAASSLRRRRPKTTITATLAIEMPSQPKLASLLAVLVLLCYCDSCFFCYADANLQQQNSIVQQQQLQAPRFTTHPSSSGSIVSEGSTKILQCHALGYPQPTYRWLKDGVPVGDFSSSQFYRFHSTRREDAGSYQCIARNDAGSIFSEKSDVVVAYMGIFENTTEGRLTVISGHPAIFDMPPIESIPVPSVMWQSEDGPLNYDIKYAFTHANQLIILSADENDRKGYRAKAINTQLGKEESSAFVHLNVSGDPYIEVAPEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAVETAGVRHTLNDPWNRTLALLQANSSHSGEYTCQVRLRSGGYPAVSASARLQILEPPLFFTPMRAETFGEFGGQVQLTCDVVGEPTPQVKWFRNAESVDAHIESGRYTLNTDNTLVIKKLILDDAAMFQCLAINEAGENSASTWLRVKTSAPIMELPPQNVTALDGKDATISCRAVGSPNPNITWIYNETQLVDISSRVQILESGDLLISNIRSVDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQPPVDTTVLLGLTATLQCKVSSDPSVPYNIDWYREGQSSTPISNSQRIGVQADGQLEIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFPPSNVKVERLPEPQQRSINVSWTPGFDGNSPISKFIIQRREVSELEKFVGPVPDPLLNWITELSNVSADQRWILLENLKAATVYQFRVSAVNRVGEGSPSEPSNVVELPQEAPSGPPVGFVGSARSMSEIITQWQPPLEEHRNGQILGYILRYRLFGYNNVPWSYQNITNEAQRNFLIQELITWKDYIVQIAAYNNMGVGVYTEGSKIKTKEGVPEAPPTNVKVEAINSTAARCRWTPPNPQQINGINQGYKIQAWQRRLIDGEWRDIERRMKTVPPSLIDPLAEQTAILGGLEKFTEYNISVLCFTDPGDGVASSQVAVMTMDDVPDEVTGLHFDDVSDRSVKVLWAPPRASNGILTGYTVRYQVKDRPDTLKSFNLTADDTELTVNQLQATTHYWFEIVAWTRVGSGIPKTATIQSGVEPVLPHAPTALALSNIEAFSVVLQFTPGFDGNSSITKWKVEGQTARNMTWFTICEINDPDAETLTVTGLVPFTQYRLRLSASNVVGSSKPSEATKDFQTIQARPKHPPFNVTVRAMSAQQLRVRWIPLQQTEWYGNPRGYNISYKQLVKTPGTIKYVPRSVVIEDHTANSHVLDSLEEWTLYEVKMNACNDVGCSKESDTAVERTREAVPSYGPLDVQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFYAAADRGQQVLHKTIPNNATFTTTLTELKKYVVYHVQVLAYTRLGNGALSTPPIRVQTFEDTPGVPSNVSFPDVSLTMARIIWDVPVDPNGKILAYQVTYTLNGSAMLNYSREFPPSDRTFRATELLPGKYYSFSCTAQTRLGWGKIATALVYTTNNRERPQAPSVPQISRSQIQAHQITFSWTPGRDGFAPLRYYTVEMRENEGRWQPLPERVDPSLSSFTAVGLRPYMTYQFRIQATNDLGPSAFSRESVIVRTLPAAPAVGVGGLKVVPITTTSVRVQWSALETALWNGDASTGGYRILYQQLSDFPTALQSTPKTDVHGINENSVVLSDLQQDRNYEIVVLPFNSQGPGPATPPAAVYVGEAVPTGEPRAVDAAPISSTEVRLLWKPPKQSMQNGDILGYKIYYLVTYSPQALEPGRKWEEEIEVVSATATSHSLVFLDKFTEYRIQLLAFNPAGDGPRSAPITVKTLPGVPSAPLHLRFSDITMQSLEVTWDPPKFLNGEILGYLVTYETTEENEKFSKQVKQKVSNTTLRVQNLEEEVTYTFTVRAQTSVDYGPGISENVTTGPQDGSPVAPRDLILTKTLSSVEMHWINGPSGRGPILGYLIEAKKRDDSRWTKIEQTRKGMMQDFTVSYHILMPSTAYTFRVIAYNRYGISFPVYSKDSILTPSKLHLEYGYLQHKPFYRQTWFMVSLAATSIVIIVMVIAVLCVKSKSYKYKQEAQKTLEESMAMSIDERQELALELYRSRHGVGTGTLNSVGTLRSGTLGTLGRKSTSRPPPGVHLGKSPPRPSPASVAYHSDEESLKCYDENPDDSSVTEKPSEVSSSEASQHSESENESVRSDPHSFVNHYANVNDSLRQSWKKTKPVRNYSSYTDSEPEGSAVMSLNGGQIIVNNMARSRAPLPGFSSFV
The following text describes a protein:
Function:
Transcriptional activator. Upon TGF-beta induction, forms a transcriptionally active complex with smad2 and smad4 called activin-responsive factor 2 (ARF2), which binds a site on the mix-B/mix.2 promoter called the activin response element (ARE). Binds to activated smads and the ARE with much higher affinity than foxh1/fast-1. Acts with foxh1/fast-1 to control the convergent extension movements of gastrulation.
Subcellular Localization:
Nucleus.
Domain:
The FM region is required for binding smad2/smad4 complexes. FM2 is more effective than FM1 and only interacts with phosphorylated smad2 that is in an activated smad complex.
Sequence:
MSFGLHPWDVAFRPSPPHNLEKKVVPPGADREKSLPSPKEDSDGAREPDSTVDLRKKNKKKKNYQRYAKPPYSYLAMISLVIQNSPEKRLKLSQILQDISSLFPFFKGNYQGWKDSIRHNLSSNDCFRKVLKDPLKPQAKGNYWTVDVTRIPPDALKLQNTAVTRQDLFPLDLAPYILHGQPYRSLERLSANHTRGRTTPRMEPEVQIPVSDPAVSFPMILWNLPTSYSKCVAPNVVAPPSIHPLLLYSNFPSISIYNYLPPPYGSPVYSDRRDLLASGLHPQIPLTPKPPELKNAPSDFPPNKTVFDIPVYTGHPGFLASQSLFSPHLPTATPPLVGYRPSGL
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of COX2 and heme A of COX1 to the active site in COX1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Miscellaneous:
MISCELLANEOUS: Present with 672 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MLCQQMIRTTAKRSSNIMTRPIIMKRSVHFKDGVYENIPFKVKGRKTPYALSHFGFFAIGFAVPFVACYVQLKKSGAF
The following text describes a protein:
Function:
Transcription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression. Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization. Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon. Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression.
Subcellular Localization:
Nucleus. Note=Accumulates in sperm-cell nuclei.
Sequence:
MRKMEAKKEEIKKGPWKAEEDEVLINHVKRYGPRDWSSIRSKGLLQRTGKSCRLRWVNKLRPNLKNGCKFSADEERTVIELQSEFGNKWARIATYLPGRTDNDVKNFWSSRQKRLARILHNSSDASSSSFNPKSSSSHRLKGKNVKPIRQSSQGFGLVEEEVTVSSSCSQMVPYSSDQVGDEVLRLPDLGVKLEHQPFAFGTDLVLAEYSDSQNDANQQAISPFSPESRELLARLDDPFYYDILGPADSSEPLFALPQPFFEPSPVPRRCRHVSKDEEADVFLDDFPADMFDQVDPIPSP
The following text describes a protein:
Function:
Transcription factor required to regulate early development. Binds telomeres and plays a key role in genomic stability by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation (By similarity).
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD
The following text describes a protein:
Function:
Capsid protein which self-assembles to form the outer icosahedral capsid with a T=13 symmetry, about 70 nm in diameter and consisting of 780 molecules capsid proteins.
Subcellular Localization:
[Outer capsid protein P8]: Virion. Host cytoplasm. Note=Found in the peripheral regions of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Sequence:
MSRQMWLDTSALLEAISEYVVRCNGDTFSGLTTGDFNALSNMFTQLSVSSAGYVSDPRVPLQTMSNMFVSFITSTDRCGYMLRKTWFNSDTKPTVSDDFITTYIRPRLQVPMSDTVRQLNNLSLQPSAKPKLYERQNAIMKGLDIPYSEPIEPCKLFRSVAGQTGNIPMMGILATPPAAQQQPFFVAERRRILFGIRSNAAIPAGAYQFVVPAWASVLSVTGAYVYFTNSFFGTTIAGVTATATAADAATTFTVPTDANNLPVQTDSRLSFSLGGGNINLELGVAKTGFCVAIEGEFTILANRSQAYYTLNSITQTPTSIDDFDVSDFLTTFLSQLRACGQYEIFSDAMDQLTNSLITNYMDPPAIPAGLAFTSPWFRFSERARTILALQNVDLNIRKLIVRHLWVITSLIAVFGRYYRPN
The following text describes a protein:
Function:
Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
Sequence:
MKIAILGAGCYRTHAAAGITNFMRACEVAKEVGKPEIALTHSSITYGAELLHLVPDVKEVIVSDPCFAEEPGLVVIDEFDPKEVMEAHLSGNPESIMPKIREVVKAKAKELPKPPKACIHLVHPEDVGLKVTSDDREAVEGADIVITWLPKGNKQPDIIKKFADAIPEGAIVTHACTIPTTKFAKIFKDLGREDLNITSYHPGCVPEMKGQVYIAEGYASEEAVNKLYEIGKIARGKAFKMPANLIGPVCDMCSAVTATVYAGLLAYRDAVTKILGAPADFAQMMADEALTQIHNLMKEKGIANMEEALDPAALLGTADSMCFGPLAEILPTALKVLEKHKVVEEEGKTKCEIMSQKE
The following text describes a protein:
Function:
Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.
Sequence:
MSKPGKGRKHSGPGKGTKEQCDRKPADKKPSEGAEKKTGASGPSGAQASGTSKTPSASGKTMNPADTQAKQTPKTEPAKSTKPTKPKEATTASSAALAAASKPTAAPSSAPVTATKPTKTKPSAAKSPPKQDIKPIPGKQQKTDSKSKDEKKSGDKVSPAVLPKMTPSSAGKVSAVATGALAAAGAAAAVTAVQSTKPKDESKEEKKAITGDKVSSGPPAKTDADAALDELLGTLEGPADIPESPQFTGPEIQDTVVTSEYLEELGKRDFTIPPEYRHLLDGKGEKMAPPTPPEEPEEHMDDDELVAALSSGFESSQASPEVKKPKLEEKMEVKPKSAAAVATQPDVQKKEVKVAAAETSKPSTQKKEEKAKIAEVSKPSTQKKEEKLAAAADTSKPSTQKKEVKATAKATAAEASKQSTESIPSEAIDELLGTLEGPPENVPGSPVFQGPEVTENITATYLEETGKRDSTIPPEYRKLLDGKDHGKDVWPSAPEPEPSMTDTELVDVFSKDFELSCSPTVQTTPAIKPKRNTEDLHECYCSKSVSQLSSSETPQGNKTKPEIAASSASTVKAAAPSGGMDSALDELLGTLEGPDPTAPESPVYTGPEVTETETAVYREGLGIRDSSIPPAYRHLLDDSAGGALLTDAPPPPPEEKPLTDDQLIDKFSMDFDCSESPATQQAHPVEPKVSSQEKKAEKEVVAASSATVKAAPTPSKAPAPPADPLDSLSGTLGVRKEEPSDKKPPVDKVKEGTGKEKKEKLGEDEKTIHPDRRLKEVKDKDGKPLLPKLEQSPKPMSEAELLDALTEGFVTSPATPDAPLQGSLKKKGSGSEDVISCSKASAVKSGAPQDAALDIQIPDDALDLLSGSLGQREVDPNENKPVVDVVKEKAKAEHIDKLGDRDDTIPPEYRKLLDGKDDKGQPAKPPAKAEEKPKKPLSDDAAIDALSSGFASCDTKSTEQPKQPSTDKTEKQCASAPVSQPSGKAPDAAKQANSAIPSVPKAGKS