lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MAENNVEAEHEWSDWALDSAEDTLIAMETLLATLRAFEDVLRQQPISMASSTEYCDNFCQALMHYAGSRNSMEHGLPLLEVYCLSINCFAAARSHLTAESDRVALVLKRLALSCFELLLSVPENEIPFEAWVQFNQSVQIAHDSLLQFGSTDLQALLQITGEGGAWSNPILTALLTGQATNPDEVEAYILLEGEGFMEMRVKHLEKMGEVAKAVVLAKACSECSFIPNQAMFRQTFVSLLCHLLPNEEAIIEISRLDCKDVLEITCNLEMEGEENTAFILCTTFLTQQLQQQNLYCSWELTLLWSKLQRRLDPSLVSLLERCLQLGAIAKTVQHLLYLVRVIQTEAEELGTPASVELCVKALQLPKQEDSETRISVCKTISCLLRNDLEVLRACQLTELLLGSSQEAFTCLEELYLRPDQKYDQENEVIPNSLRCELLLALKAYWPFDPEFWDWKTLKYHCNFLLGLNAESEGEGEQEKEVKTKKLEVPVVQKRVETDLHCRINGGLGSHEHQDKKEPHPEVDASSEVKREKFCCKICKRSFTDTQIVHHSKRHSQENNHLCPVCLEKFKSRKDLVPHMKKHIGSKSIPSQNNTKDDEEDDVEPGEITLDPSLVLYYNSTRDPDLLHHIVQQTKTSKEKSPDDDEYVTFDYIEHHFKLQNRDEYPCPGTKCKRVFKHSKYLYVHLKSDHKGDENVKYFHQMRDKREKCVFCRRHFVSAYHHRKHRRAHYGDQPYTCVVVGCGAKFSTSNELVVHKQTHGYQLSYQCELQGCYVTYADLGQLYHHEAQHFRDAAFACCSTECKKYFLSKKEFMKHLSTHKITFTEEDFEAQRKAKRKLFKIITEPPVGFNQLSDPTDGVNGEVLNPPSMSCASSVEDFPNKEPKATMTLVAVCFDGSKFTCGFEKCGMTFSRARDVQRHLKCAHPEHLKLENREHKHDKEQGSKGMDTNVAPDGEEKETDEHSAPLKPVETDKKTATPPKSNETSFLSRHAKNDGLKEILLGLSKLSLNSVPLSSPSEPSQSSQDASLKFSHQAILEKPPVVLLNKNSDMSDEQMVVAKEEYTESLGNAKPYVCVYAGCGFRTAKSYSLLRHYISKHGCSLEEARKMTSFKTTSFKPYACQLCSKSHREKHVLRAHYIQAHKMSGALVDKISCGTVQLEQDKKSSSQPLSNIDPKGIKKETVIMEHQQKSNTPSLISENGQNSDNHSPSEGEGEDEVGRKEDNEEQKEEDETKTTQQVRTRRLVAKNNLCYILDKFSKPFHCVAKNCDAAFSTQGGLVRHLQFIHHYNRSQLLLDKDSDVQGPEVRKEPARKRAQPNPDEPQPQFKCHFANCHAVYHLKSSLVRHTRDFHSQPPELIRCKHEGCSRVFSHSSALKKHMLYSHCEYYDSLVVRLQSTHKKSITGCQNKLVVSQEGCQKTDAGSPDTHDGTSSPRAEGTEQLEENRGNSSQKKKESGAKKSKRANVSDLVLRSHEEALQMCQDRCLRMAYPCMVQGCDSVVKYLHSVHRHYMKVHHLGREELHKNADTLVFHAERLEELIQRKSAQPAATGAGSPNEGQEKETLKESESPEEQPEPTGVPSVPAESESPEEQPEPTGVPAESESPEEQPEPTGFPSVPAETQDGGSPDPPISTEEQKEEKEEPSPVETNEVPVGSNEVVEGEASTDEKPEEMPVAPQSSPKLEERLSLDQIRPLLRPVTVDLSPPYSLRFAPEESSQDTSEHKEDCKMVNGSAAVSSPTVRLPLKRKNEISEQPSNVKDTQPSSPQHSFDITAYKPIGFESSFLKFIQETAPKDEEALVKRRDTFKRSCSVKENHHLGISHTRGRRTHSPLLKSNSTTGDFTSIQNLKSILDKALAGCGDLAIKQLQFLKPVVVLGRPVCTTLPDLFPSDTNNSKLLLGS
The following text describes a protein:
Function:
SNARE required for targeting and fusion of ER-derived transport vesicles with the Golgi complex.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MGSRFGRRKERNGDMLPLYESQSPQHLDSLENENDERISKLTGKVKSLKELTMNIGTEITSSTKLMESMNDSFDSTKSLLSGTMTRLKNVSKNGGISIWMWLAFFCLVALILVLVRF
The following text describes a protein:
Function:
Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. CpG methylation of the recognition site greatly inhibits DNA binding, suggesting that DNA methylation may regulate the MYC:MAX complex in vivo. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements (By similarity).
Subcellular Localization:
Nucleus. Cell projection, dendrite.
Sequence:
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGGTISAFDGGSDSSSESEPEEPQSRKKLRMEAS
The following text describes a protein:
Function:
A acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MASSEGKIAFVSNLNGTTLTEVSLGSFLAPVCFLSRGLFLIVFHLGKGVLPFSWGAHLMLDFTTIIMPMVLSCTALSDILHFVIMGIAVVDFAVLYLVYKRKKNPSSLKSTIDKFIQSRAESKMVPFVTIFRVLVNVKTAISILAVDFSVFPRRYAKTETYGTGVMDFGVGAYVMANALVCPEARGKNIQGSKISHVLKQAVSVWPLILLGFVRLASVKSSGYHEHVTEYGVHWNFFFTLAIVRVVASALLALFPVNCSGFLALIICGTYQVILETTDLKSFLIHNTERSGFLLANREGVFSVVGYIAIYMAGVHVGCYLMQSRNLVKDWIRVIRNLLLTSFGLFLVLYVCQRNIEPVSRRMANLPFCIWTVAQALFFLSCISIADVVLLFAKVVSNFSLVPTSWCPNQNKKADEKTRRDMDGLCLIQAVNRNQLLYFLLANVLTGLTNVFVDTMNSRDVLAVSVLLWYMFMNSLVIFILHVNKITVKFW
The following text describes a protein:
Function:
Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Also cleaves PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Sequence:
MEVLQQESPGSCLTVWLVFAATALLILYLTWNYTYFLRRGIPGPLPFPVLGNVLDWKEGVQYALDGYIKKYGNCCGFYQFLTPAILVADPDMIKQIMVKHFDRFHNRMYIPVDNPMLRSALFLSSDDQWKKIRHTLTPAFSGRKMKLMSEMVREPASRLVQNLKKVCGTDRQGIVELKELFGAYIMDTIGLCAFGLNVDSQKNKDDPFVLNAKRFFSSLDFTSPAMIISMLTSKIPGVSHILPLLGLTVFPPEVLEFFIAIIDQAVEQRKTNKAAKTVDFLQLVIDSTKDNACEDEDDDDDATTNGTSSSSHAIDKKRKRQALTRQELTSQALAFFVAGYETTTTALCFTAYLLATNPDQQDRLIDEIDRLVPTAEDITYDNLKKLTCLENFISESLRLYPPGALIDRVCNQTTTINGHVFQAGDSVSLPIWSVHRDPEHWPNPEKFDPDRFNKENAAGRAPLAWLPFGGGPRFCIGLRFAMMEIRTATVMLLQQFRLEVAPETEIPPVLGKMGFINPPNGITLRVVERSK
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Has a role in telomere silencing, which is the repression of chromatin structure which leads to a stop in the transcription of nearby genes. Also has a role in the regulation of telomere length. Acts as an alkyl-hydroperoxide reductase in the nucleus during post-diauxic growth. Preferentially reduces alkyl-hydroperoxides rather than hydrogen peroxide. Acts as an antioxidant necessary for stationary phase survival.
Miscellaneous:
MISCELLANEOUS: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin; MISCELLANEOUS: Present with 1840 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MGEALRRSTRIAISKRMLEEEESKLAPISTPEVPKKKIKTGPKHNANQAVVQEANRSSDVNELEIGDPIPDLSLLNEDNDSISLKKITENNRVVVFFVYPRASTPGCTRQACGFRDNYQELKKYAAVFGLSADSVTSQKKFQSKQNLPYHLLSDPKREFIGLLGAKKTPLSGSIRSHFIFVDGKLKFKRVKISPEVSVNDAKKEVLEVAEKFKEE
The following text describes a protein:
Function:
Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
Subcellular Localization:
Secreted.
Sequence:
HIRLPAWSLLLPLLMSLPLSLSVFHTKVSGSRPRGPRYAEGTFISDYSIAMDKIRQQDFVNWLLAQKGKKNDWKHNITQREAGALELAHQSNRKEESREQQGSLPKNPGDEDLLKDLLIRELLAWMVDQMEVCRLRWGCSVALGILSRGHMLEL
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MDYAARRRNQGGLFEGLYRVIMRRNSVYVTFVIAGAFLGERAVDYGVHKLWEYNNVGKRYEDIPVLGQRQSEE
The following text describes a protein:
Function:
Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines.
Subcellular Localization:
Lysosome.
Sequence:
MINKFLTIFLIFSIVIIKVLSQSSNEQPLNVVPYPQEVTMIGCNIPLSVGSISIKSNIESTILSISISRYQSLFFPFVSNNVLKDSSSNIELSLIIASDDETLELGIDESYFLLVNQDTYQIKANTIYGAMRGLETFKQMVVYDVVENSYSLTCAEVVDYPTYQWRGLLVDNARHFLPKNMVLHIIDSMGYNKFNTMHWHLIDTVAFPVESKTYPKLTEALLGPGAIITHDDILEVVAYAKTYGIRVIPEFDVPGHSASWGVGYPELLSNCPGYPQSSIPLDCSNPYTYSFLENFFSEIAPLFQDSYFHTGGDELVIDCWANDTSIQKWMKTNNYNTSDAFQYFEDQLDVILKSINRTKIAWNDVLQHGVKFDKETTLVQTWTNINDLRDVLAAGYKTITSFFFYLDRQSPTGNHYHYEWQDTWEDFYASDPRLNITSNAENILGGEATMFGEQVSTVNWDARVWPRAIGISERLWSATEINNITLALPRIGQFSCDMSRRGISSGPLFPDFCSLPDDLSFSFKPVYQLSKDEIKLILKKK
The following text describes a protein:
Function:
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MAQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYLYRKQISITPTKADIAAVQLPTGVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTVTYQGCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTSETSKPAAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPWMAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAFFGWAFITSLQARRAWMRIVQIILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYADWCVACKEFEKYTFSDPRVQQALGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFNTQGQEQPQSRVTGFMDAATFSAHLHDRQP
The following text describes a protein:
Function:
Methionyl-tRNA formyltransferase that formylates methionyl-tRNA in mitochondria and is crucial for translation initiation.
Subcellular Localization:
Mitochondrion.
Domain:
Composed of an N- and a C-terminal domain. The N-terminal domain carries the tetrahydrofolate (THF)-binding site and the C-terminal domain is presumably involved in positioning the Met-tRNA substrate for the formylation reaction.
Sequence:
MLLPRCCWGRWLMGRRPRCSCQAPAGFDGKDGRGSRVREKPPWRVLFLGTDHFARETLRALHAARDGKEEKLIEKLEVVTVPSLSPKGLPVKQYAIQSQLPVYEWPDVGSGEYDVGVVASFGRLLSEALILKFPYGILNVHPSCLPRWRGPAPIIHTVLHGDTVTGVTIMQIRPKRFDIGPILQQETIPVPPKSTSKELEAVLSKLGANMLISVLKNLPESLNNGRPQPAEGVTYAPKVSAGTSCVKWEEQTSEQVLRLHLAIGDIVPLQTLWMENTVKLLDLVEVNNSILADPKLTGQTVTPGFVVYHRPSQMLLVRCKDGWIGVRSVMLKKTLTATDFYNGYLHAWYQKNSHAHPSQCRFQTLRLPTKMQQKTKLLLCNSALSS
The following text describes a protein:
Function:
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Localization:
Nucleus.
Domain:
The F-box is necessary for the interaction with ASK proteins.
Sequence:
MGAASSSIVRSEPFAGKLCGLEDVPENCITAMFMYMEPPEICLLARVNKSFHRASRSDAVWEDKLPSNYKFLVRRILEDQQQVGVKDKLIYRKKEIYARLCRPNLFDTGTKEAWLDKRSGKVFLAISPKAMKITGIDDRRYWEHISSDESRFGSITYLRQIWWLEAVGKIRFEFAPGKYSLLFKIQLGKPIRKCGRKTCSLDQVHGWDIKPVRFQLSTSDGQCAMSERHLDESGRWVYHHAGDFVVENQNSPVWVKFSMLQIDCTHTKGGLCLDCVIICPFEYRGKYKYSD
The following text describes a protein:
Function:
Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B. Also functions as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3. Binds to the rhodopsin promoter in a sequence-specific manner.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTQDPPHLESLLPHLSCLPPTSLPPLSPSPSSSSSFSSLNASSPSKPFDIDVNSIAGVSDKELQQLSVRQLNQRLHGQDRQVVSMLKAKRRVLKNRGYALNCRQRRMQNQAQLESDNLQLRDQIRTLRQMITDLQSRVFYYEQNHHSLHPQNDLPVAVSVMESSDITPYPSSHWSPNHHSSFESSLSSSIKEEDSHSSPHQY
The following text describes a protein:
Function:
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MGKKEQFLKRKLEKSAEESDEPDSGAESVENEELLNVVNGEDADSSDSDGEIEESDEDLNDSDDEIEESDEDDSNTTDEESDENELENEENAAEDTANPARDEYSSHDTSDEEDIRTTVGNIPMNWYDDFKHLGYDWDGNQIIKPESGDLLDTFLKRMEDPDFWRTVKDPQTGQNVVLSDADIDLIKRLKANQIPDATFDEYAPWIEWFTSEVMKTPLRKFPEHKRSFLPSKSDAKKVSKLVHALKMGWIKTRAEAEKLRAKKEPEFYMLWATDDQAEDMRRIHKHIPAPKRLLPGHAESYNPPPEYLFDEKELKQWNKHKNAPWKRKLHFVPQKFESLRHVPAYPRYIKERFLRCLDLYLCPRGIKMKLNIEPEALVPKLPSPKDLQPFPTTLSIEYKGHGDMVRTISTDKIGQYLVSGSDDGTIKLWEVNTGRCLKTIDTGGVVRSVEWCPNPALSLILVAASNRVLLINPHLGDTLITSKTDSVLETAPQSDAIVSERIKTTVEWSESIDPKEYTQGVRIALKHFKEVAQVTWHGKGDYFATVMPDGLNRSVLISQISRRRSQIPFTKSKGLVQCVLFHPTKPCLFVATQRHVRIYDLVKQTLMKKLLTNSKWISTMAIHPGGDNLLVGTYDRKMLWFDLDLSTKPYQTLRLHGTAVRGVAFHKRYPLFASGSDDKSLIVCHGMVYNDLLKNPLIVPLKRLQDHETNNDFGIFGVLFHPLQPWVFSSGADGTIKLYSN
The following text describes a protein:
Function:
Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
Subcellular Localization:
Cytoplasm.
Sequence:
MRQTHPTTYELTSSSTDSRTDPELQRLLESTWSERHDAGVGFRYRLHIERERIAEGKFNFLILLNRKRLTERRQPQAFQLDAPFDPSRFNFTRVDPAEVQLELVAPSPTTMLINNSPVTVYHSLVVPDRAGQHSQLLTSGGVRVAFELLLRLPDRRYRIGYNSPGAQASVNHLHLHLLRIDTALYVQRAELLPVRGTPLLHRLADHLPAQGYCFVLRDPTTELEPVCSGLMKLIQALAERQMAHNLFWTWTDLHRGGELRALVFPRVTQCVNKAACSFNAAFLELCGFVSVGEGNDYDRLTEEAIVQALREAQGDVYGMLGGIFPVASTD
The following text describes a protein:
Function:
Removes the 4'-phosphate group from tetra- and hexaacylated lipid A species, has no 1-phosphatase or Kdo hydrolase activity. Absence of the 4'-phosphate group renders the bacteria resistant to host-derived cationic antimicrobial peptides (CAMP), allowing it to camouflage itself from the host innate immune response, and plays a critical role in the long-term colonization of the host's stomach.
Miscellaneous:
MISCELLANEOUS: In this organism most lipid A is tetraacylated without a phosphate group at the 4'-position and a phosphoethanolamine residue at the 1-position.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MKKLKGLFLSLLLWVYPLKSEPINEGAYILEEIGDVLRFLPIFVGTVSLAMRDYRGLGELAVGTLVTQGVIYGLKGAFSTAHKDGARVGFAKRPCCNSWRGMPSGHAGGAFSAAGFVYYRYGWKPALPVIALAILTDTSRVVAGQHTILQVTIGSLIAWGFAYLFTSRYKPKRWMLYPEISSDFKGSSRYGVGFSYQW
The following text describes a protein:
Function:
Component of the cell wall involved in virulence. Does not seem to have a major role in maintaining cell wall integrity but plays a role in the relationship between C.albicans and the host.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Sequence:
MKFLAILSLSSSALATISSIQLFAKSDDSKVDGLGLYSKHEGAAIDYLFLGKNGADLKYDDEKKQIFQELKTSSITVRQSFTLGGDVYELGATDNFIPVTINKDGTLSFTGDDKVYASKNVNDPYRYSESEYAVSNKKTDDSAPITIVAKFSDDKAAETSGVAQAASSSAGPAQASVSNFEGAAGQNKLSYGVGMAAVVAGLVM
The following text describes a protein:
Function:
Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids. Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
AQNPNMEQNWNGTSNNGTLLDSNEIDDLVGVIYSVVLVVTLVIVMFSMGCSSDTQKLWFHMKKPWALCTGFLCQAGLMPLSCFLFALAFKMKASHAIAVIMMGSCPGGITSNLATYWMDGDIDLSMCMTTVSTLLSFGTLPLCFFIYTSKWTAAGSISIPFEKIGLTMVSVFVPTSFGLLLNVKWPATARCIAKVGVSLGSFLLIACMVVSIILYKDMWDMDASLLFTGIITPCVGYGFGFLLARMACQSWKRCRTISLETGVQNATMCSTILQVSFPKMMVGEMVFYPMVYSCSFTFFAIVLIAAYRIYRGYRKKTDADLMRTEVVFTALTRESTDGMNTDDFPSSSTEKKMGENDV
The following text describes a protein:
Function:
Represses the expression of the yvmC-cypX operon, which is involved in pulcherriminic acid biosynthesis. Also negatively regulates yvmA, yvnB and its own expression. Positively regulates yisI expression. Acts by binding specifically to a 14-bp palindromic motif, the YvmB box, which is present in the promoter region of the target genes.
Sequence:
MSDLTKQMIYDIYVRLLHLNEQKANTSLQQFFKEAAEEDVAEIPKNMTSIHVIDCIGQHEPINNAGIARKMNLSKANVTKISTKLIKEEFINSYQLTDNKKEVYFKLTRKGRRIFDLHEKLHKKKELAFYQFLDSFSQEEQKAVLKFLEQLTSTLEAEQTDGTPDKPVK
The following text describes a protein:
Function:
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole.
Miscellaneous:
MISCELLANEOUS: Present with 20200 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSEESLFESSPQKMEYEITNYSERHTELPGHFIGLNTVDKLEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLITHKMTAEKPDPTLAVICGAATKAFLASEEARHKYIESLQKGQVLSKDLLQTMFPVDFIHEGKRYKFTVAKSGNDRYTLFINGSKCDIILRQLSDGGLLIAIGGKSHTIYWKEEVAATRLSVDSMTTLLEVENDPTQLRTPSPGKLVKFLVENGEHIIKGQPYAEIEVMKMQMPLVSQENGIVQLLKQPGSTIVAGDIMAIMTLDDPSKVKHALPFEGMLPDFGSPVIEGTKPAYKFKSLVSTLENILKGYDNQVIMNASLQQLIEVLRNPKLPYSEWKLHISALHSRLPAKLDEQMEELVARSLRRGAVFPARQLSKLIDMAVKNPEYNPDKLLGAVVEPLADIAHKYSNGLEAHEHSIFVHFLEEYYEVEKLFNGPNVREENIILKLRDENPKDLDKVALTVLSHSKVSAKNNLILAILKHYQPLCKLSSKVSAIFSTPLQHIVELESKATAKVALQAREILIQGALPSVKERTEQIEHILKSSVVKVAYGSSNPKRSEPDLNILKDLIDSNYVVFDVLLQFLTHQDPVVTAAAAQVYIRRAYRAYTIGDIRVHEGVTVPIVEWKFQLPSAAFSTFPTVKSKMGMNRAVSVSDLSYVANSQSSPLREGILMAVDHLDDVDEILSQSLEVIPRHQSSSNGPAPDRSGSSASLSNVANVCVASTEGFESEEEILVRLREILDLNKQELINASIRRITFMFGFKDGSYPKYYTFNGPNYNENETIRHIEPALAFQLELGRLSNFNIKPIFTDNRNIHVYEAVSKTSPLDKRFFTRGIIRTGHIRDDISIQEYLTSEANRLMSDILDNLEVTDTSNSDLNHIFINFIAVFDISPEDVEAAFGGFLERFGKRLLRLRVSSAEIRIIIKDPQTGAPVPLRALINNVSGYVIKTEMYTEVKNAKGEWVFKSLGKPGSMHLRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGAPAINKMLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQEPGQVWHPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPQGMVGIKFRREKLLDTMNRLDDKYRELRSQLSNKSLAPEVHQQISKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHQVGEASRLEKIARIRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGLKLESFAQDLAKKIRSDHDNAIDGLSEVIKMLSTDDKEKLLKTLK
The following text describes a protein:
Function:
This enzyme catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
Miscellaneous:
MISCELLANEOUS: Present with 1580 molecules/cell in log phase SD medium.
Sequence:
MPVEFATNPFGEAKNATSLPKYGTPVTAISSVLFNNVDSIFAYKSFSQPDLLHQDLKKWSEKRGNESRGKPFFQELDIRSGAGLAPLGFSHGLKNTTAIVAPGFSLPYFINSLKTVSHDGKFLLNVGALNYDNATGSVTNDYVTALDAASKLKYGVVTPISANEVQSVALLALAIATFSNNSGAINLFDGLNYSKTVLPLVESVPEASILAKLSKVIAPDAAFDDVLDKFNELTGLRLHNFQYFGAQDAETVFITYGSLESELFNSAISGNNSKIGLINVRVPLPFNVAKFVTHVPSTTKQIVVIGQTLDGSSPSFLRSQVSAALFYHGRTSISVSEYIYQPDFIWSPKAVKSIVSSFIPEFTYNADSSFGEGFIYWASDKSINIDVASKLVKALSLEDGKFVSLRTKFDNLANAGTFQAQFVTSKEQIPVSNIDSTKLSVVEDVSLLKHLDVAATVAEQGSIALVSQKAVKDLDLNSVESYVKNLGIPESFLISIAKKNIKLFIIDGETTNDESKLSLFIQAVFWKLAFGLDVAECTNRIWKSIDSGADISAASISEFLTGAFKNFLSEVPLALYTKFSEINIEKKEDEEEPAALPIFVNETSFLPNNSTIEEIPLPETSEISDIAKKLSFKEAYEVENKLRPDLPVKNFVVKVKENRRVTPADYDRYIFHIEFDISGTGMTYDIGEALGIHARNNESLVKEFLTFYGLNESDVVLVPNKDNHHLLETRTVLQAFVENLDIFGKPPKRFYESLIPYASNEEEKKKLEDLVTPAGAVDLKRFQDVEYYTYADIFELFPSVRPSLEELVTIIEPLKRREYSIASSQKVHPNEVHLLIVVVDWVDNKGRKRYGQASKYISDLAVGSELVVSVKPSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQKQQGYEIGEVFLYLGSRHKREEYLYGELWEAYKDAGIITHIGAAFSRDQPQKIYIQDRIKENLDELKTAMIDNKGSFYLCGPTWPVPDITQALQDILAKDAEERGIKVDLDAAIEELKEASRYILEVY
The following text describes a protein:
Function:
Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
VKILLRFLICHLTLLFMSQCAFAMIKQDKSRMRREVKALTVTTIKQEPYTMEKGTEFEGFCIDLLNEIAKKLDFRYNINLVKDGFYGRQDAEGNWNGMVGEVVRGEADLAVAPLTVTAVREKAIEMTKPFMQTGIGIILRKDLVTSEANFFEFLNPFSKETWIGILIAYLVTAFCLCIVARMSPCEWSEPQSEDNHFTLLHSLWYAAGALTLQGAGPQPKALSVRVISTIWWLFTVVLLASYIANFSSMLGSDTTQFSIGSFEDLAKQDVIEYGTLRTSSTLAFFKSLETPLERDNYSSQSKSTPAQNNQTLGVRFGSSNHHALDYTIAPMDFSCIRHICRSKHEELIITLLLSCSLNTGSPLVKNLSVAILEMSESGDLDYLRNKWWASTCLQGDVEGSPLKPHSLGGIFLVLAVGLALGVFLAVLELAFKSKMSAEQQRKACCSVFSDELSQRFRSSTVKKTQEPSEKSKA
The following text describes a protein:
Function:
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
Sequence:
MASTATTPAGGSGLASTDDAAVMSRFRELVPQLGGNYKGAHGKVAVIGGCLEFTGAPFFAAMSALRVGADMAYVICTPSAATAIKSYSPELMVLPYLHEAAAAAAWPGGAGEDKVDMVAVSRAVDRILPWLQRATAVVVGPGLGDDPAVCEAGAALLHHARALGLPVVIDGSALTHIIAQRPEYAVGYSNCVLTPNVAELGRIGAAVGVHLPGRMSDAWQVHAPSIAQAFGGPVVVAKGPTDLICVPSSPPHAAADAAAASPSPSPSTSGQELRPLLECKDPGALRRCGGQGDVLAGTIAAFLCWAVKQQGGSKASAAQSSGVRPSSTSTTTTSGGGLEPGTTAMCVYAACKVMRGAAAEAYRVQERSLLAGDIIPHLYPTFRRVVGGP
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
Sequence:
MSIAFNSSYLDEIQTAIRSRPIPWDGYVRANLLTPDEAALIKTIEKQSPEARKETVKKDLTHYATSFVSLLRKIPREDVAKYILSFVASLVQELPEFAQAMLELSKLDSDSPFGPLLKLLESEDEQIQLLAVKSIVVLLADSKTVDLTTEKYAAQYLQFVGLLIGSSASVQVQDVGTVSLAVLLSNRSYRPLFWKFNSELVPKLLDIIKADKGGLHLQYYTLLVIWLESFDNKAAHQLVSSFSELIPTLLQAARTSVKEKITRLCVAIIVNVLKAAPKDTVASLLLNQGQAVFKNFSDRKWTDEELIEDIEVVYTQLNEEVARMTTFDRYYAEIKSGKLSWTPAHKSEFFWQENVGQFKDDDWKVLKMLAGIVKSATDPTVQAVACSDVANVCKLLPDAIQVLQDDGAKLKIMELMSSDNSEVRFEALKATQVFVAQSLK
The following text describes a protein:
Function:
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
Subcellular Localization:
Cytoplasm. Mitochondrion inner membrane. Mitochondrion matrix.
Sequence:
MSRSYQEAVEALNTFHNAAELEKQRKSGGRDLTRSLPETRDYMRRLNITNEDLARMRIIHVAGSKGKGSTAAMCDALLRQQGFSTGLFTSPHLIEVRERIRVNGAPLSRAEFASTFWELYDALDATPPADDILNFPTYFRATFLMALLAFKRLKLDAIILEVGIGGLYDATNVVLEPWVCGITRLGLEHTSILGNTLTEIAHQKAGIMKENVPCFSQPQEPTAWRALEEAATQHRPKFLLQTDPLPPVAMHGHIPPLNLGIAGAHQFFNAGLAVQLVRYWTRRYRGTAPDRSGRTQVLRRGRTVYYIDGAHTVDSCQAAASWVRSKLPHPSSTQGGPCRVSMIFNCTGDRLPADLLQPINHTISLASQRRHPEICRTAFLGLEYLKLSRKLQARDTTQVELESQVFVVDSIECAIAQLEHAAIPAKQDEGLDSRDELLDGPEQHVIVTGSLHLVGGFLAQIGMEVQ