lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in transcription regulation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPQLSSTTPRKYPGRKVGAARSSSAASPSPWGARRGRASSRAGPARGTRGSARPGSGPLNWGVRVCPKRRFLPFSMSFPVLIRWWSKQGRRAAASRRRAAAGAETLPGRGPRARPPRPAASRRPGPGPARRPAWEPAKDRMTENMKECLAHTKAAVGDMVTVVKTEVCSPLRDQEYGQPCSRRLEPSSMEVEPKKLKGKRDLIVTKSFQQVDFWFCESCQEYFVDECPTHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKEVGGESDVRCINEVVPKGHIFGPYEGQISTQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIRPGERLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKAEQALDNPEDLRGPSHFPVLKQGRSPYKRSFDEGDLHPQAKKKKIDLIFKDVLEASLESANAEGRQLALSTSLVIRKVPKYQDDDYGRAALTQGICRTPGEGDWKVPQKVAKELGPLEDEEEEHTSFKADSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKVPEPPILPQQVLELPEFSDPAASESMVSCPAIMEDDDQEVDSADESVSNDVMTATDEPSKLSSATGRRIRRFKQEWLKKFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQLYKLRMHPEKTEEMCRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMNEGDCQILIHHIARALREDLVERIRQSPCLSIILDGQSDDLLADTVAVYVQYTSSDGPPATEFLSLQELGFSSTESYLQALDRAFAALGIRLQDEKPTVGLGVDGANITASLRASMFMTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMCELRSTASTLCEETEFLGDIRAVRWIIGEQNVLNALIKDYLEVVAHLKDVSSQTQRADASAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYIFQGEYLLVSQVDDKIEEAIQEISRLADSPGEYLQEFEENFRESFNGIAVKNLRVAEAKFQSIREKICQKTQVILAQRFDSRSRVFVKACQVFDLAAWPRNNEELLSFGKEDMVQIFDHLEAIPAFSRDVCREGMDPRGSLLMEWRDLKADYYTKNGFKDLISHICKYKQRFPLLNKIIQVLKVLPTSTACCEKGRSALQRVRKNHRSRLTLEQLSDLLTIAVNGPPIASFDAKRALDSWFEEKSGNSYTLSAEVLSRMSALEQKPMLQAVDHGSEFYPDM
The following text describes a protein:
Function:
May act as an effector for ARL3.
Subcellular Localization:
Cell projection, cilium, flagellum. Cytoplasm. Nucleus.
Sequence:
MAAEEEDEVEWVVESIAGFLRGPDWSIPILDFVEQKCEVFDDEEESKLTYTEIHQEYKELVEKLLETYLKEIGINEDQFQEACTSPLAKTRTSQAILQPVLAAEDFTIFKAMMVEKNTEMQLQAIRIIQERNGVLPDCLTDGSDVVSDLEQEEMKILKEVLRKSKEEYDQEEERKRKKQLSEAKTEEHPMQANETAKMSNSQGDGEHFAHPASEVKVHFANQSVQPLTRKLEMLPETSSLPQKGLKIPGFEHASMEGPIANLSTLRTEELRQREHYLKQKRDKLMSMRKDMKIKQNQTSEQKGKPAGEVESARLLCPRDFPGNNTGVGCHFLLQGIFPTQGLNLRLLVGKQILNN
The following text describes a protein:
Function:
Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA).
Sequence:
MSLNLVSEQLLAANGLNHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRENGEGKVKTLAAVAHQPLYTTLDPLQSMSREEKLDILRRVDKAAREADKRVQEVNASLTGVYELILVAATDGTLAADVRPLVRLSVSVQVEEDGKRERGASGGGGRFGYEYFLADLDGEVRADAWAKEAVRMALVNLSAVAAPAGTLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQIGEQVASALCTVVDDGTMMNRRGSVAIDDEGTPGQYNVLIENGVLKGYMQDKLNARLMGAAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTTPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA
The following text describes a protein:
Function:
Catalyzes the deimination of arginine residues of proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MFEQVEAAPPAPSVKDSPAGTEHHRTCRLDINKPQHVLYVVGTSLDVSIYRSAPPSSKSFSVKCTPQVKYSISPPTPETSHQSQIPLNRNTSLLISMDRASEFENESKLSVRYYNEDRYAVGLAVLHLTAVEISLDVDADRDGIVEENNPNKGSWKWGPSGYGAILLVNCDSESKFCKNEDYNSKQEFIFNLSDLKDMSPMKLRTRGPSRLPKGYKLMMHICLGDSEKIRVFGSKSGNKQVNNAENSSSVKDYPVVLGPEVLSQEVPYPGGNAEMDFHVEGLDFPDKDFDGLVTINLSLLKPISDAVPETPIFTDKVMFRVAPWIMTPNTLQPEEVFVCRTFDNQQFLKEIKALTSKIGYKLNICEPVMNRGDRWIQDELEFGFVDSPHHRFPVVLDSPRDRELKNFPCKVLLGPDFGYVTREPQSDEVSTMDSFGNLEVSPPVTVNGKKYPLGRIIIGVAFPTAKNGRNMTKVVQDFLWAQRVQKPIALFSDWLVVGHVDEFMTFVPAPDRKGFRLLLASPDAAYKLFKDLKNNGHGQARMFDGLPKERQITVDEILGDRVLESHNNYVQSCIDWNRDVLKKELGLDDDDIIDLPILFKLEAEEGFRAGALYPDMVNMIVLGKNLGIPKPFGPKVNGRCALETEMCSLMGGLGLNCTFIDDYYSYHKNLGEVHCGSNVRRKPFRFQWWNMEL
The following text describes a protein:
Function:
Functions as a two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Domain:
Histidine-containing phosphotransfer domain (HPt) contains an active histidine that mediates the phosphotransfer.
Sequence:
MAAKGKDLSQQLEELISSLQEQGILTDYFDELRGLQDDNNPRLVDEIITIFLRVAEDYRAELTRNLSEPDVNYSEVHKLATWFKGSTTSNACGRVALACQELVDASEAKNKEGCLVALEAVNREYLVAKENLNRIVGMEREIYNMRLPKAT
The following text describes a protein:
Function:
Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.
Subcellular Localization:
Endoplasmic reticulum membrane.
Sequence:
MARPSLDDITPELERVWSTDPSSPDVSIHSYAHSPVHAAVLSKDHAALNAILRILPKPALEGSVLTEEQSIKAEEDAEAASAMIDRRDVPGKESALHMAVRVKDPVALELLMLAGADISLQNVGGWTALQEAVCAGEPALAAIIMREYQSLAWAKWLRRLPRLVATMKRMRDFYMELTWNFESSVIPFIGKIAPSDTYRIWKRGASLRADMTLEGFDGFRIKRADQSILFLGEGTPDGRVKPGGVIVLMHKEKEIADALEGAGGSLSDADLAADVADLFKTNVHRAGLDVTKATLVPVKTWRRHEKEEAVGPWQSKVIDMHHVMVTFRSRKVPGAMSDEELFNLRPEDEDAGSARSDDDYADVLTEEERKQLKEAMENAPSIDLDSEAGVNEAGEDGSERSLTPKESAAEIGAGAEKGLRNGGEGAGSLTPERGRSKEGAPLLGSASTSESEGLVPSEKPARKSWFGWGRKQHASSESPSENVTDADGSSRSGADSIQSPMHSKRGSKHQGGEERKEETGSEMEFSKGLKPTLWLTDGFPLRVEELLPLLDLLSPRVKAVRRLRELLTVKMPRGTFPVKVAIPIIPTIRVVVTVSKFREVARLAPPGTEELEEDEFEDAQSEMPKRGWMEWVRGAPGENESGERTSGDGAGGPGAADAFAIPADYAWVSSEEKRRRDREKKQQKRLKKGKGKVGSSEQNQKG
The following text describes a protein:
Function:
Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
Subcellular Localization:
Cytoplasm.
Domain:
ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site; The C-terminal coiled-coil domain is crucial for aminoacylation activity.
Sequence:
MTTEHNEINMPTKYEPSNVEAGKYKWWLEKEFFKAEGNTDKEPYSIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGFDTLYLPGMDHAGIATQAKVEAKLKESNISRYDLGRENFVDKTWEWKEEYAEFIREQWEKLGLGLDYSRERFTLDDGLSDAVKKVFVTLYNKGLIYRGQYIINWDPEAKTALSDIEVIHKDIEGSFYHLKYPLTDGSGYLEVATTRPETIPGDTAVAVHPKDERYQHLIGKTIMLPILNREIPIVADEYVEREFGSGAVKITPAHDPNDFEVGNRHNLPRIIVMHEDGTMNENAGKYDGLDRFVARKEIIQDFKDLGLFIKQEPHLHSVGHSERTGAVVEPYLSLQWFVKMEPLAAEALELQKTENKVNFVPARFEKTYETWMDNIHDWCISRQLWWGHRIPAWYHKETGEIYVGEKEPENLSEWEQDEDVLDTWFSSALWPFSTMGWPDTESPDFQHFFPTNTLVTGYDIIFFWVSRMIFQSVEFTGERPFKDTLIHGLVRDSEGRKMSKSLGNGVDPIEVIDKYGADSLRYTLATGSSPGQDLKFSYEKVESTWNFINKIWNASRFVLMNLDGMKYNEIDLSNVTEVSDKWILTRLNETIQAVTSLGEKYEFGEVGRTLYNFIWDDFCDWYIEIAKIPLYGEDEVAKQTTRSVLAYTLNATMRLLHPFMPFVTEEIWQNLPHEGESITIAEWPKVNEQQIDTKSSTAMATLVEVIRAVRNIRSEVNTPLSKPIVLEIKPKDTTYKEILEQNISYIERFCNPEQVTISFDVEASKTAMTAVVSGAEIFIPLEALIDLNVEIARLEKELEKWNKEVARVQGKLNNERFISKAPESVVAEERLKEKDYLDKKASVLERIETLKEV
The following text describes a protein:
Function:
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
Subcellular Localization:
Cytoplasm.
Domain:
Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
Sequence:
MKTDELREKYLAFFETKGCVRQPSDVLVPAWDPSVLFTPAGMNQFKDHFLGKVKLDFTRATTCQKCLRTGDIDNVGRTAFHHTFFEMLGNFSFGDYFKEEAIHWAWEFLTDKKWLGIPGERLTVTVYKDDDEAFGIWHDKIGLPTQRISRMDEDENFWPASAPSEGPDGVCGPCSEIYYQLEDGSDVEIWNLVFTQFNRVGTPPDNLHPLPSKNIDTGMGLERTASVLQGVPTNFHIDSLFPIVEAASEVCGVKYEYESDNGRRLRRITDHARASVFAVHENVYPGPKDARSVIRRLIRRAVLDGYQMNLREPFLYKLVEAVADASKAAYPELGQTTQRVSEAIESEEKAFFSTIDGGMKRIHRLFEEMNDEASVMVPGAEAADLLTTYGVPPELVQTLAAEQNFTFDWSGFREAMDKHADESDGGQRVLFQTGPLETLKEALRETPFVGYEQTEATAVVKGIITGDGKGKGDDGQLLSHLDRPEDAVLRLVLDHSPFYGESGGQVGDIGVISNDNFEFEVIDTQRHASMIVHHGRLIRGKINEGETCTAKVDVENRTALARAHSATHILHHALHTHVGRHAEQQGSKVEPDRLRFDFTNPKAIDDETLVKIEQDVLGMVGKGDEIRWDTVSLADAREAGAMMLFGEKYPDPCRMVSMGTFSRELCGGTHLTNTKQVGSFEVVVEESVSTGTRRIEALTGERAKEHREQTQALLNEVAGKLNCDASVAAAATVALIEEVRRLKKELSSGKAADYPAEFVFDAKAAKAETTDISDYNAVRAAVRGLTRRLNVAITDVLSRLDSLLADRSKLVEQLKQVTAGGKISADDLIADGTKVGDTLLIVAETPGANPNIMRGWIDQIRKKSDTPTAVLLASSMNDKVMLVGGLSRDLVDRGLKAGDWVGAAAKVVGGSGGGRPDMAQAGGKDASKLPEALQQARETMTEKLG
The following text describes a protein:
Function:
May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MKRFLFLLLTISLLVMVQIQTGLSGQNDTSQTSSPSASSNISGGIFLFFVANAIIHLFCFS
The following text describes a protein:
Function:
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MVKIKNRYYVIRMITNDGSQPTPHKPLIFRELMKLAAEMFGDFGYSILKMSLSVRVLDEDVIVLRVAEGGNKYFGAILPCVHKIDKQPMVLQTIFIGRSMRSCEKRLIKIRQDELHSALKQCTTTETRIQILGAIKDICGNCGPTRIFSDEQRKDQSNS
The following text describes a protein:
Function:
Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MSLTVSAQDASAAPYDAQLYVAIDCEFVGVGPEGAHDQLARVSLVDYFGSVLLDVFVQGPRPVVDYRTEVSGITPELVQEGVEFNAARLAVVKLIDGKVLVGHSIKHDLLVLQINWKKYSLRDSQDHRPFLRRDRPQKLKYLARGIGLSIQSGEHSSVEDAQAVMAVYRAHKDEMDRCCDHYNT
The following text describes a protein:
Function:
Baseplate central spike complex-associated protein. Makes the tip of the central spike which probably punctures the host outer membrane, a necessary step for viral DNA ejection into the host cell.
Subcellular Localization:
Virion. Note=Present in the baseplate.
Sequence:
MSGLSYDKCVTAGHEAWPPTVVNATQSKVFTGGIAVLVAGDPITEHTEIKKPYETHGGVTQPRTSKVYVTGKKAVQMADPISCGDTVAQASSKVFIK
The following text describes a protein:
Function:
Required for assembly of the mitotic spindle. Interacts with spindle microtubules to produce an outwardly directed force acting upon the poles. Following spindle assembly, CIN8 and KIP1 apparently act to oppose a force that draws separated poles back together. This force seems to be mediate by KAR3.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle.
Sequence:
MRKSYRPSMSSTRPKTRSSMAPSTGMKVLVRCRGRNERETTENSSVVVKTSGHKGREITIEGGPVAHTGKTYTFDRVFGPESDQGMIFEAVSSSLDEMLQGYNCTIFAYGQTGTGKTYTMTGDFNLDERGEAVSNAGIVPRALVELFKRLSGSAGENSVKLSYVELYNEELRDLLSSQGDTKKLRIFEEPGKKGTVVQGLEEAYVRSCTEAMKVLQEGFTRRQVAATKCNDMSSRSHSVLTITLSTKEYTADGQEYLRTGKLNLVDLAGSENVGRSGAENMRAREAGSINQSLLTLGRVINSLVDGTLHIPYRESKLTRLLQESLGGRTKTVIIATVSPARVSIDETISTLEYSHRAKNIKNSPVVNETTSKQVFIKDYVDEIARLRADLESTRKGQGVFLSQESYQLLLDENESHKVTINEQKMRLDVLEERAGNYEGKIKDMEEQQAVVIKGAKSLLKVMDSAVAEVTKLHEHTRLMGEIGVRNETGLRSLQQSAPKRLKLCVGTHKNDVAHYVTKTSGGLTALDGLQERNNQFFGDLTQRLDSSITSIQAQIVHLISSNNQDAHSMASLLSELGAVKHEMKTNIQASMAHIQTSLQDVTSDLEKHIESYETQLTNSLSQLSSNLSQSVASVRQTYERVQQQIDQAVTSHLNTTSTSTKSIHTSFESMSATVARQKEAQAAAEAELKQRMNQMIESALKEQNDQWDAVVGALKTEVHRELSAVNGSIETFKGAYGESRNQVDFSAVSGTAHQLTEESINLKEATRNVFDRVESGHSSLCRVVDSHSDSVTSVMSPLDSFVVQATETNQNLSEARAKRMDEISSAFEAGLSSTAQTISVYSDTARSDSEAVKSELKTGIESVAHCVKRLASEVDQVSGHIEEHLYEKFPSAPPRSSYVDVATDFRAVVEKGNLKGHTRDPLHEVTNEM
The following text describes a protein:
Function:
Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates.
Subcellular Localization:
Nucleus.
Sequence:
MSSPRKDLAESGKDPKGEDSDMKNPNPCSLSLCHDDLPSSSQKMAPRSVNCEVFENEVNSGMVKSFLQDFQHSDDFEDQFKEEAESKGEPNSWTTGGSSLKDSKDEELAGPSQTYIPTLQGMEITSERELAQLALVQPIVVSNHEQSTFQDYFKMLEKKLSENEIIQEFMALEFKNLHAVFHSGNELQNREKNRYRDILPYDSTRVPLGENKDYINASYIKIVNSEQEYYYIATQGPLPGTTDDFWQMVLENNSNVIVMITREVEGGVSKCHHYWPVSMKKPLELKSCRIFLENYQILQYFVIRIFQVVRKSTGISHFVKHLQFTKWPDHGTPASAEDFIKYVRYVRKSHLTGPLIVHCSAGVGRTGVFLCVDVVFCAIEKSFSFNIMNIVGQMRQQRCGMIQTKEQYIFCYKIVLEVLQKLLTKK
The following text describes a protein:
Function:
Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes (By similarity).
Subcellular Localization:
Nucleus.
Domain:
The LisH domain is required for the activation of histone gene transcription.
Sequence:
MLLPSDVARLVLGYLQQEKLSSTCRSFILESPNLREYAEHYTDEGSIPGCVLSLFGKNLTTILNEYIAMKAKENKEEIPVMVSALWKKLDHTLSQIRSMQNCLVLPTSQKVRTRYGIQDLRHQRMLTSHAASTGSAVALQQTSTPIAAKQVMLRSFTSQSASQTIVSPLCSGQSTIQCTNSPATESKGETLQNSALSDAEKKQTSSPMRRKTDCQRRRRAAPLNSSSATHEGETEGNVDSLQDLIDGNFPQLVIENAREKILSNKSLQEKLAENINKFLGSDTATQASKLSEGGALEQYTSIDEILGLQGGEMHMSEEAIHDILEQTELDPDFQELYDLFACSSTKPTKLASRDPSLQTEGVATTSIHVANDNLEPMESSFDASVDTSHSSNHSEVGAAQKKDGRSQLVVPSPTPKVTESTGMPSKVQEMPISASERQSMSDRSVESKKSIDSVIILDNTGSDTVIESNEEVQVTSMEVGISQSQDVDMNVLHTEVIGADCQLAVEQGSLNMLTVDLTVPNLKEETPKMQTYEKASEAKKSSPLKDEVQALGSRRLERNKSEGAEGPCTTESQNIVVLVSIGSTVTESNLLNQRGDLPATPRKTDTSTETTVSEQMQAESSITSKELKVLQKQASKTPPHPMVPPISPSIKGSSSDSDGSSLPLEVSSSVGVSTPVNTSNVEQNCSDVSSVDPSQIITLSFITEDIAEDAELTKAVKSISERSNSALLLSPFHKPQESSSIVSIPGPTSETLTLLADPREVVNVSGDVATGVKPAEDCTIISLPGASNLSTDGGIIQLMPATSSSFAPSGSFFISTCNTGGAQQSNIMVVPSNCAPASTQKQPCHFQTPPRPHSVYTVGQAISPKLSQGSTFILASAVQPVLPGVMGMFPVSVVGQSSNTFTTPSHQVLHVPVSQGVPKLSLPPKSQKPVPPRTLASAAEKQGTAATTDSGNRKSSSRMQRSENVDKNLAAMSQNKPEERQTSTTNPSTKGTENHKRVLCFENTAANRGTPNTKSLCNSAAPQNKDKVETMNTSSSSLPAKQNNKDSGKADKTAPSTEANSKCESVPSKQPVVPATKDLSGDKKPVAVASSPDVLGGVMANKENMLQKENKKQELPEVSKKSSTADGAAGNLERTVQAVHETGRKHATLPSILRRTKLSTERMCPPSPLTKQASDLLQSMQFNSPNAKHFSGGDLPIPRTPGSGIDDRLVDSHQDHMKTPKSKRYPEDGGTPKPMLPPATPELPACSPASETGSENSVNMAAHTLMILSRATLAKTDGSSPLKDNTQQIKLSKNSSKKRKLDEPDEYGRRPHKKELMSPSAILKRKKMKKHRKKSTDDFPAGMDVDKFLMSLHYDE
The following text describes a protein:
Function:
Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Acts as the major regulator of early endosomal vesicle trafficking, particularly at the trans-Golgi-network/early endosome (TGN/EE), but is also involved in the endocytosis process. Together with VPS45/BEN2 required for polar PIN-FORMED (PIN) proteins localization, for their dynamic repolarization, and consequently for auxin activity gradient formation and auxin-related developmental processes (e.g. embryonic patterning, organogenesis and vasculature venation patterning). Target of hopM1, a conserved Pseudomonas syringae virulence protein that directs the protein to its own proteasome-mediated degradation. Plays a broad role in PAMP-triggered immunity (PTI), effector-triggered immunity (ETI), and salicylic acid (SA)-regulated immunity.
Subcellular Localization:
Cytoplasm, cytosol. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Soluble and partially membrane-bound.
Sequence:
MAAGGFLTRAFDTMLKESGGKKFPDLQKAIQAYQDGSKVVTQAAPSSIVESSQAEGGGEKTGVEADEPQKVTSAEVAQQASQSKSETINVSLANAGHTLGGAEVELVLKPLRLAFETKNLKIFDAALDCLHKLIAYDHLEGDPGLDGGKNSAPFTDILNMVCSCVDNSSPDSTVLQVLKVLLTAVASGKFKVHGEPLLGVIRVCYNIALNSKSPINQATSKAMLTQMISIVFRRMETDIVSASSTVSQEEHVSGDTSSPKNEEITAADENEKEMTLGDALTQAKDTTLASVEELHTLVGGADIKGLEAALDKAVHLEDGKKIKRGIELESMSIGQRDALLVFRTLCKMGMKEDSDEVTTKTRILSLELLQGMLEGVSHSFTKNFHFIDSVKAYLSYALLRASVSQSSVIFQYASGIFSVLLLRFRDSLKGEIGIFFPIIVLRSLDNSECPNDQKMGVLRMLEKVCKDPQMLVDVYVNYDCDLEAPNLFERMVTTLSKIAQGSQSADPNPAMASQTASVKGSSLQCLVNVLKSLVDWEKIRREAENSTRNANEDSASTGEPIETKSREDVPSNFEKAKAHKSTMEAAISEFNRNSVKGVEYLIANKLVERNPASVAQFLRSTSSLSKVMIGDYLGQHEEFPLAVMHAYVDSMKFSEMKFHSAIREFLKGFRLPGEAQKIDRIMEKFAERYCADNPGLFKNADTAYVLAYAVIMLNTDAHNPMVWPKMSKSDFTRMNATNDPEDCAPTELLEEIYDSIVQEEIKLKDDDTMKKLSSQRPGGEERGGLVSILNLGLPKRISAADAKSETEDIVRKTQEIFRKHGVKRGVFHTVEQVDIIRPMVEAVGWPLLAAFSVTMEVGDNKPRILLCMEGFKAGIHIAYVLGMDTMRYAFLTSLVRFTFLHAPKEMRSKNVEALRILLGLCDSEPDTLQDTWNAVLECVSRLEFIISTPGIAATVMHGSNQISRDGVVQSLKELAGRPAEQVFVNSVKLPSESVVEFFTALCGVSAEELKQSPARVFSLQKLVEISYYNIARIRMVWARIWSVLAEHFVSAGSHHDEKIAMYAIDSLRQLGMKYLERAELTNFTFQNDILKPFVIIMRNTQSQTIRSLIVDCIVQMIKSKVGSIKSGWRSVFMIFTAAADDEVESIVEKSFENVEQVILEHFDQVIGDCFMDCVNCLIRFANNKASDRISLKAIALLRICEDRLAEGLIPGGVLKPVDGNEDETFDVTEHYWFPMLAGLSDLTSDYRPEVRNCALEVLFDLLNERGNKFSTPFWESIFHRILFPIFDHVSHAGKESLISSGDVKFRETSIHSLQLLCNLFNTFYKEVCFMLPPLLSLLLDCAKKSDQTVVSISLGALVHLIEVGGHQFSEGDWDMLLKSIRDASYTTQPLELLNALSFDNPKKNLVLAGDIEADASDSPRVDRNPDDIKDNGKVSAQASPRIGTHGTSLESGIPPKADGSEGRPSSSGRAQKDVDDVNLQRSQTFGQRFMDNLFLRNLTSQPKSSVAEVTVPSSPYKHEDPTEPDSREEESPALGAIRGKCITQLLLLGAINSIQQKYWSNLKTPQKIAIMDILFSFIEFASSYNSYSNLRTRMNHIPTERPPLNLLRQELEGTTIYLDVLQKTTSGLADDASNSEDRLEGAAEEKLVSFCEQVLKETSDLQSTLGETTNMDVHRVLELRSPVIVKVLEGMCFMNNTIFRKHMREFYPLLTRLVCCEQMEIRGALANLFKAQLKPLLQQ
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MPPKAKKALTAGSKELYYEDQQLADDIVILEEKLKGLKRVYLDRMTALAERKQQELVLSAELDARKAGLEAKKSEKIDVLTDGTRVYKVRERIALQEIATQDAALHELQETKKKLQEQLETCTADFDSRIKSKKREFESLRERTADMEKEFAVLLSDVEQCSP
The following text describes a protein:
Function:
Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of all iron(3+)-hydroxamate siderophores such as ferrichrome, gallichrome, desferrioxamine, coprogen, aerobactin, shizokinen, rhodotorulic acid and the antibiotic albomycin.
Subcellular Localization:
Periplasm.
Sequence:
MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA
The following text describes a protein:
Function:
Hydrolase highly specific for thiamine triphosphate (ThTP).
Subcellular Localization:
Cytoplasm.
Sequence:
MNVFRLQTHRRIVLSAVDMEVKEGGSARGEGGGGGGGEGARAADHNNKPAGVIEVERKFSFGEGSEEKLKKAGAVCKETTSFHDVYYDTEEFILTLADHWLRKREGNWELKCPPSSRDQASLVEQYVELQREADILKQLAAILNVEAASVDEMIRLARCEPFCNFQTDRKTYTLDGGFKIDLDQTDFGFRVGEIELICQKQADVPEALCRIDALAEKLGFQSSKKIPGKMSAFLKTFREKHYAALVKGGLLTPIT
The following text describes a protein:
Function:
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Involved in axon regeneration after injury, probably downstream of dlk-1 and mkk-4 and upstream of mak-2. May phosphorylate mak-2. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord.
Subcellular Localization:
Nucleus. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Cell projection, cilium.
Domain:
The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
Sequence:
MASVPSSSSLPVSHVRRHEDVSTPSAPPTKRSNNQSQPPESYEPNTWLQQQREQEQQKKLAAENIKKQSIEATGNNEMVGEEEEDILSKPCGPHKRRFQFVMIRNITFAIPEGYDVEPNSIEYLGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHHARRIFRETKLLQLMRHDNIICALDIYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRALKYIHSANIIHRDLKPGNLALTDDSDLMILDFGLARSLEKKDTSLTQYVQTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELLTKIENDNSSAIKAVIQSYTTHKRRNFRDVFSAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQHPYLAEFSLPEDEPRADHIFDLDDSQARTRFEWRDAVWKEIMNYKRLSSSPLIPGEADR
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
Sequence:
MPQPNRPRKGSMGFSPRKRAESEVPRFNSWPADDGEVGLQGFAGYKAGMTHVVLVDDKANAPTEGMETTVPVTVVETPPMRAAAVRLYEDTPYGKKPLTEVWADDTHESLDRTLSVPDEGGDTDELIEALDTEEIADIRVITHTVPGDTAGVPKKNPDVMETRVGGGTLADRLEFAADLIEDGGVHAFGDVFRAGEFTDAAGITKGKGTQGPVKRWGVQKRKGKHARQGWRRRIGNLGPWNPSRVRSTVPQQGQTGYHQRTELNKRLIDINDGDEPTPDGGFPNYGEVDGPYTLVKGSVPGPEQRLVRFRPAVRPNESPRLDPEVRYVSTASNQG
The following text describes a protein:
Function:
Catalyzes the deamination of dCMP to dUMP, providing the nucleoside monophosphate substrate for the thymidylate synthase/TYMS. Also, part of a nucleotide salvage pathway that eliminates epigenetically modified 5-hydroxymethyl-dCMP (hmdCMP) in a two-step process entailing deamination to cytotoxic 5-hydroxymethyl-dUMP (hmdUMP), followed by its hydrolysis into 5-hydroxymethyluracil (hmU) and 2-deoxy-D-ribose 5-phosphate (deoxyribosephosphate). Catalyzes the first step in that pathway, the deamination of 5-hydroxymethyl-dCMP (hmdCMP).
Sequence:
MGGDGRARSPPACHVARPERWARRCGAPGSRPGTWERRAPRMLPSRLKLLLGRLCGAGSARETRRRTPRPPGGFLPRPNMSEVSWRKRDDYLQWPEYFMAVAFLSAQRSKDPNSQVGACIVNAENKIVGIGYNGMPNGCSDDLLPWRRTAENKLDTKYPYVCHAELNAIMNKNSADVKGCTMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFDMAGVTFRKFTPKCSKIVIDFDSINSRPTQKPQ
The following text describes a protein:
Function:
Activates the JUN N-terminal pathway during dorsal closure.
Sequence:
MPSQVSRGLDTTNMLPISEEQQLQQQQQQQQLEQLHHPQIPEIPIPDLEQVETQVGDGSLWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGDVGWWTGKIGDKVGVFPKDFVTDEDPLQLNVSSAIGDIQPHEIEYNELDIKEVIGSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCLNTKLCLVMEYARGGSLNRILAGKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSKFTLTPQESFHYMQECWRKEIAGVLHDLREKEKELRNKEEQLLRVQNEQREKANLLKIREQNLRERERVLIERELVMLQPVPSKRKHKKGKKNKPLQISLPTGFRHTITAVRDKAEQPGSPSFSGLRIVALTDGHKGKTWGPSTMHQRERSLLPSQLSGGQPEWPAQTSTHSSFSKSAPNLDKKQQQQNQQQVASLTPPPGLGILGGSGGAGGTPATPLLYPGIPIILTRPNNNNIGNCKAITTTITTTTTTTTNNNNNNNNSISANNNNQLNNISTINSNNNNNQTNLTSQPNTIIVLQNGRNNSNSSTTSQSPAKIYHRARSQEYGLDHPLAYQPPPLYLVTDDSSETDTVASPTGCFHFLKSGNSSAASGAVHLHRFGGSLGNSPAVGRKKHSLDSSSHHPPANGSNSFALPNQLTLPSEDNNTYDHAFYRDVIKKMSMASSERVNSKSSGDLTMYNSSTPLTARDCDDAEEAFEGGRFQRNFSGSQFPRHCFFTRQEEEGEAEDEDAVAAEVDTADADADDECQVPASQMRQNSTTSRKSSVTFQSVSFEEPDFVATPRTTARSDLYTSSASISFATYRSASPSLSSSSTTASASPSIASTEAVNGYHMQENSILNTRRMQDVQPHPDVIKLRAQEQRQQTKNQKKQRPKHITKSKSVEAPVEGQHHEHDDHNDPQHQHHSAGSSKIRALFNLFTRSRKKYSKLAEHNMVGGPEFCAIDPYQTDLAMGGSSRSLKRKGKKPQTQSCEQLERC
The following text describes a protein:
Function:
Modifies the specificity of McrB restriction by expanding the range of modified sequences restricted. Does not bind to DNA.
Sequence:
MEQPVIPVRNIYYMLTYAWGYLQEIKQANLEAIPGNNLLDILGYVLNKGVLQLSRRGLELDYNPNTEIIPGIKGRIEFAKTIRGFHLNHGKTVSTFDMLNEDTLANRIIKSTLAILIKHEKLNSTIRDEARSLYRKLPGISTLHLTPQHFSYLNGGKNTRYYKFVISVCKFIVNNSIPGQNKGHYRFYDFERNEKEMSLLYQKFLYEFCRRELTSANTTRSYLKWDASSISDQSLNLLPRMETDITIRSSEKILIVDAKYYKSIFSRRMGTEKFHSQNLYQLMNYLWSLKPENGENIGGLLIYPHVDTAVKHRYKINGFDIGLCTVNLGQEWPCIHQELLDIFDEYLK
The following text describes a protein:
Function:
May act as co-chaperone for HSP90 (Potential). Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell (By similarity). May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen (By similarity).
Subcellular Localization:
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Predominant in the perinuclear region. Little protein in the nucleus (By similarity).
Sequence:
MTVSGPGTPEPRPSDPGASSAEELRKEGNELFKCGDYEGALTAYTQALSLGATPQDQAILHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTGETDLMLAALRTLVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVMFDALKEGVKKGFRGKEGAIIVDPARELKVLISNLLELLTEIGVSGQGRDNALTLLIKMVPRKSPKDPNNSLTLWVIDQGLKKILEVGGSVPEAAGELTVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIRSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQEEEQLVAVEALIHAAGKAKRASFITANGVALLKDLYKGSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDEAALKALFQLSRSEERSVLFAVGSALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMTCMVKTESPVLTNSCRELLSRVFLALVEEVEDRGTVVAQGGGKALLPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLSCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDELLRRAAAGGLAMLTSMRPSLCSRIPQVTTHWLEILQALLLSPNPELQHRGTVVVLNMMESSKEIASTLMESEVLEILSVLAKGEESPVTRAAAACLEKAVEYRLIQPNQDGE