lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MLPPRSCAGKNFHSSHAASPYTRKIGLPRGTPTRGGAAELSGSDVARECRSRGSRQRRLLPAPRGRAAATSEPPWHMRSGAPRERLRFSSDLRMPPERRSRTKGDRRAGAMPRRKARPGSGSTPGKAARSSQRTLPAGPKAAPSAISAAEEESRLRQRNRLMLENDKPAAERCLEQLVFGDVEDDEDALLRRLRSSRGHLHGSSDDSEVEDEAVDNLSQKKPVWVDEDDEDEEIVDMMNNRFRKDMMKNASESKLSKDKLQKRLKEEFQHAMGGVPDWAEPGSKRKTSSDDESEEDEDDLLQRTGNFISTSTSLPRGILKMKNCRPANAERPTTARISSVQFHPGAQVVMVSGVDHAISLFQVDGKTNPKIQSIYLEKFPIFKACFSANGEEVLATSMHSKVIYVYDMIAGKLIPVHQVRGLKEKIVKRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMKINGRISASTFSSDSKRIYTSSGNGEVYVWDVNSRKCINRFLDEGSLYGLSIAASKNGQYVACGSKSGVVNIYNQDSCLQQTNPKPIKAIMNLVTGVTSLAFNPTTEILAVASRKMKEAVRLVHLPSCTVFSNFPVYKKSTLSRVQTMDFSPRGGYFALGNEQGKALLYRLHHYSDF
The following text describes a protein:
Function:
Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3.
Subcellular Localization:
Cytoplasm. Cell membrane. Note=Cytoplasmic before PDGF stimulation. After PDGF stimulation, localized at the cell membrane and peripheral region.
Sequence:
MNGAGPGPAAAAPVPVPVPVPDWRQFCELHAQAAAVDFAHKFCRFLRDNPAYDTPDAGASFSRHFAANFLDVFGEEVRRVLVAGPTTRGAAVSAEAMEPELADTSALKAAPYGHSRSSEDVSTHAATKARVRKGFSLRNMSLCVVDGVRDMWHRRASPEPDAAAAPRTAEPRDKWTRRLRLSRTLAAKVELVDIQREGALRFMVADDAAAGSGGSAQWQKCRLLLRRAVAEERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTELSCTRGGCLASRVASCSCELLTDAVDLPRPPETTAVGAVVTAPHSRGRDAVRESLIHVPLETFLQTLESPGGSGSDSNNTGEQGAETDPEAEPELELSDYPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVLDMLRHFHTHPIPLESGGSADITLRSYVRAQDPPPEPGPTPPAAPASPACWSDSPGQHYFSSLAAAACPPASPSDAAGASSSSASSSSAASGPAPPRPVEGQLSARSRSNSAERLLEAVAATAAEEPPEAAPGRARAVENQYSFY
The following text describes a protein:
Function:
Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes. Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17, COX19, MICU1 and COA7. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Required for the import of COA7 in the IMS. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS. Reduced CHCHD4/MIA40 is then reoxidized by GFER/ERV1 via a disulfide relay system. Mediates formation of disulfide bond in MICU1 in the IMS, promoting formation of the MICU1-MICU2 heterodimer that regulates mitochondrial calcium uptake.
Subcellular Localization:
Mitochondrion intermembrane space.
Domain:
The CHCH domain contains a conserved twin Cys-X(9)-Cys motif which is required for import and stability of MIA40 in mitochondria.
Sequence:
MSYCRQEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGNINWNCPCLGGMASGPCGEQFKSAFSCFHYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEEGSS
The following text describes a protein:
Function:
Molecular adapter that acts as a bridge between a variety of multiprotein complexes, and which is involved in antifungal innate immunity, development of the muscle and sister chromatid cohesion. Plays a role in antifungal innate immunity by acting as a bridge between components of the NuRD (Nucleosome Remodeling and Deacetylase) and MEC chromatin remodeling complexes. NuRD and MEC complexes bind to the promoters of antimicrobial peptide genes and may recruit other proteins such as ceh-18 to control gene expression in response to fungal infection. During meiotic prophase I, plays a role in the disassembly of synaptonemal complex proteins and in the regulation of chromosome condensation and segregation. Together with nuclear import receptor ima-2, required for the import and load of cohesin complex proteins in meiotic nuclei, possibly by acting as a bridge between ima-2 and cohesins. Required for embryonic development of muscle tissue.
Subcellular Localization:
Nucleus.
Sequence:
MACGLALKRPLQHEYESFLTDETYNGEAKRARTQCPPFRAQMGTIAATLPSTSTFAQKFKEQEESVFQAATLMTRLSRNQLKTYLSSEVKNLRKRKAIPRSNDFDDDGDQRGDGCSSNYSKAYRAPSSPKSGSDSEGEAPSTSVTDRSSAKREFTMANVQMICERLLKQQEIRLRNEFEMVLTKKLDEQHQQYVQFAAEQLNSKCVSTGDDYSYSYLS
The following text describes a protein:
Function:
Monooxygenase component of a two-component system involved in the biosynthesis of the side chain of the aminoglycoside antibiotics in the biosynthetic pathway of butirosin. Together with BtrV, mediates hydroxylation of gamma-L-Glu-GABA-S-BtrI. Not able to hydroxylate free substrates, activation by the acyl-carrier protein is mandatory. Octanoyl-S-[BtrI acyl-carrier protein] is also accepted as substrate.
Sequence:
MIALDTIQYYGQIPGVNHYNGKKEFMENAVKIAQLSDAYGIVGSLSFFNHSVLDPWAVSSVIMRHTERHVPLIALQPYMYPPYTAAKLIQSFTYLYDRRIDLNMITGAVTGELQQTGGYIDHSSRYKKLHEYVQVLRLLLESDSAVSFKGDYYELNNLEFKPLLPDKRLFPRIFMSGSSEEGLETGLKAADFVVTHPGPLEHFKRHFSEKVQGSAVQSAIRIEIIARESAEQAWKIAHARYPGNRQGKIQLRMKTNSESSWQRMLAELALASETYDEVFWMGGYMNGGIYSPVLVGDYEQVAAYLNEYYKLGVKAVLLGSMYSEEDFIHFSRVKEGISNPV
The following text describes a protein:
Function:
DNA-binding protein that binds to both double-stranded and single-stranded DNA without significant sequence specificity to reversibly repress the transcriptional activity of chloroplast nucleoids by promoting DNA compaction and possibly regulate DNA replication; Essential protein with sulfite reductase activity required in assimilatory sulfate reduction pathway during both primary and secondary metabolism and thus involved in development and growth.
Subcellular Localization:
Plastid, chloroplast stroma, chloroplast nucleoid.
Sequence:
MNSLKEMTLGVSAPFAAFDGLRVSAAGQQRATVRGVSLPGSLDVRAVATPVKPPTTMPPKRSKVEIIKQNSDFLRHPLKEDLTTDAPNVSEDAVQLIKFHGSYQQDNRELRGPGKKAYQFMLRTKNPSGIVPNRLYLVMDELADKYGIGTLRLTTRQTFQLHGVLKTDLKTVMSSIIHNLGSTLGACGDVNRNVLAPAAPFKTTEYMHATELSTKIASLLAPQAGAYYDIWVDGEKITQDEPEDVTLARNDNSHGTNFEDSPEPIYGIQFLPRKFKIAITVPGDNSVDVLTNDIGIVVVSDEHGEVEGYNLYVGGGMGRTHRNEATFPRLADQLGFVSKDDILYVVKAIVATQRDYGRRDDRRMSRMKYVVEEWGIDKFRTVVEQYFGKKIQPFKDIPEFKFQSYLGWHEQGDGHLFFGVHVENGRIKGEAKKVLREVIEKYSLNVRITPNQNMILCDVRPSWRPRITKALAAVGLVSPRYVDPLNVTAMACPALPLCPLAIAEAERGAPDILKRIRNLFEKVRLKSTESLVVRITGCPNGCARPYMAELGLVGDGPNSYQIYLGGSPNQTRLAESFMERVKLDKLESVLEPLFYMWKSQRQVGESFGDFSFRQGFGALKTYIENYTEPRKSRRKVGVYLDTDVHANLSKAAEGQGVSASQLASKVLAEFLHQGDS
The following text describes a protein:
Function:
Major facilitator transporter involved in fusarinine C (FsC) uptake. In contrast to TAFC-mediated iron uptake, FsC-mediated iron uptake via mirD does not play a significant role during infection.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLSSWQKKFFQTPEHPPAEGIAPPRDDGVPNPEPVTYPDTKYPSDVVNHDAGEMLPNEEAQDGVTQAEAITLTWSKISLGAAYFLMWLLYLVNGFQASITGNLSAYVTSGFESHSLIPVISIVSSVMSAATYMPLAKVLNLWDRSIGFIIMVAFATLGLILSATCHDIGTYCAAQVFYSIGFAGIIFSVDVITADTSTLRDRGLAYAFTSSPYIITAFGGPAAAEHFYDSNWRWAYGCFSIVLPVVALPMFCLLRWNRHKAKKSGLLKDKADSGRTWMESIRHYIIEFDILGVFFLAAGLVLFLLPFSIAGSTEDDWKSASIITMLVIGFVCLLVFALVERFVAPVPFLPWALLASRTVLGACMLDVCYQIAYYCWFNYYTSYLQVVYGTSITTAGYITSIFDVVSGVWLFIVGFLIKKTNRFRWLLFIAVPLYILGVGLMIYFRKPSWSVGYMIMCQIFIAFAGGTMIICQQVAVLAASDHDHAASSLAFLNVFGTMGSAVGSSISGAIWTHTLPGALQRLLPDSVKADWQTIYDSLEEQLSYERGTLIRQAIALAYASTQSKMLIAGTAIMALSLVWMFVIRDIKLTKTQTKGVLF
The following text describes a protein:
Function:
Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKNINLILAWLVHIFTASGLIVGLYSIISIVNGNYSLLLKLTVIGLIIDGIDGTMARKLKVKELIPEIDGTLLDNITDYINYTFIPVIFFYLGEFIEEKYKVAICIGILLSSAYQFSRTDAKTNDNYFRGFPSLWNLFVILNIIFKMEQITNLITMSICIITSFIPIKFIYPSKTKELRKITIPITIISCLIFVVSIFSELSTTALKMAKTVLILYFAYLTLASIYLTYKTRNR
The following text describes a protein:
Function:
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
Sequence:
MFQNSMKQRMNWEDFYGPNLGYALELYDQYTQDPNSIDPDLKEMFDELGAPPSDIKEASGTKEKGRVTADLIQKIASAVRLAEDIRTYGHLNASVNPLRKDEKKSELFPLSDYGLTEEEIKAIPASVICKDAPKNISNGLEAIQYLRNTYKRTISFEFDHVHDFKEREWLTRKIESGELFQKNSAEKLSAVLERLTEVEGFEQFLHRTFVGQKRFSIEGLDALVPVLDDIIAQSVKSGTTSVNIGMAHRGRLNVLAHVLGKPYEIIFSEFQHAPNKDLVPSEGSIGISYGWTGDVKYHLGANRELQDAETKSARITLANNPSHLEFINPIVEGSTRAAQETRTQSGYPVQDETKSLAILIHGDAAFPGEGIVAETLNLSSLKGYQVGGAIHIIANNMIGFTTESAESRSTKYASDLAKGYEIPIVHVNADDPEACLSAVKFAVEYRKTFNKDFLIDLIGYRRYGHNEMDEPSTTQPMLYDAVRKHPTVKQIFAEKLVKEGVVTEEVVQNIEKSVTKRIEDAYQKVPSKKEHTACEIELPEPVSNGFPDVDTSIDFDVLRKLNGELINWPESFNVFGKLKRILERRAKAFDDDRKVEWSLAESLAFASILKDGTPIRLTGQDSERGTFAQRNLVLHDSETGKEFVPLHHLSDCSTSFAVHNSPLSEGSVLGFEYGYNVHSPETLVLWEAQYGDFANAAQVYFDQFISAGRAKWGQKSGLVMLLPHGYEGQGPEHSSGRIERFLQLAAENNWTVANLTSAAQYFHILRRQAKMLLREEIRPLVIMTPKSLLRNPNTVSEVQELSESRFQPVYEQSGLSHDYEKVTRLVLSSGKVSIDISDHFNKLEDGKEWLHIARIEQLYPFPAKGVKELFAKLPNLKEIVWVQEEPQNMGAWGYISPYLTEIAPEGVSVQYIGRRRRSSPAEGDPTVHKKEQERIVSDSLTRKN
The following text describes a protein:
Function:
Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipid hydroperoxides that can be further reduced to the corresponding hydroxy species. Shows increasing catalytic activity within the series arachidonic acid < 5,8,11-eicosatrienoic acid < linoleic acid < 8,11,14-eicosatrienoic acid.
Subcellular Localization:
Cytoplasm.
Sequence:
MVKYKILVATGDSVFAGSANLVHLWLVGEHGEADLGKQLRPLLGRKTELEVDVPLHLGRLLAVKLRKQKGLLDSDWFCKSITVQGPGTQGEAFFPCYSWVQGKETICLTEGTALKVTDDTQNLFRKYREQELENRRNVYRWGSWKEGLILPIAGSTERDLPRNQRFMKDKDLDFSLSLVKELKNFAIKGTLDFVSRVQKLEDYQKVFPHTKTALPERVRGSWKEDALFGYQFLNGANPMLLRRSMRLPARLVLPPGMEDVQTQLEKELKAGSLFEVDFSLLDGVKPNIIIFKQQYVTAPLVMLKLQPDGRLLPMVIQLQPPRHGCPPPLLFLPSDPPMAWLLAKIWVRSSDFQLHQLQSHLLRGHLMAEVISVATMRSLPSLHPIYKLLAPHFRYTMEINTLARNNLVSEWGIFDLVVSTGSGGHVDILQRATSCLTYRSFCPPDDLADRGLVGVKSSLYAQDALRLWEIISRYVERMVELFYRSDTDVKEDPELQVWCREVTEVGLLGAQDRGFPLSLESRAELCRFVAMCIFTCTGQHASTHLGQLDWYAWIPNGPCTMRKPPPISKDVTERDIVDSLPCLQQARMQITVTKFLGRRQPVMVALGQHKEEYFSGPRPRDVLKQFQEELAIMDKEIEVRNASLDLPYEYLRPSLVENSVTI
The following text describes a protein:
Function:
Receptor for basic fibroblast growth factor.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein.
Sequence:
EVAGESTDSNTIKWCSTLLIEHASLLDSGKYSCHLLSNVRTESSVNIKVYEKSFINVLSTPTTSSNVIEVIKGEMAAIKYSVHAFPTPTFNWFNGTQSISRSSISTTTQLSNDSRVSTNGSTLLIKNVKFSDSGWYMLSVSVKNLMINETFLLSSPDPLPARIENLDPFINADIGDDVLLSCNTTGQPAPTVTWYHEDIIVQESKLSELMIRRVKQVDGGVYICVAENQYGKDNKSVSLNIQGDHQMQIMFAASGVSCLVLILACGLIAMRLRKKVKHEKCMSALLNIKDMPLEEQAQCSEYDSKKWEFPRDRLRFGKTLGRGAFGKVIQATAFDLEKSSSCKTVAVKMLKVGSRSNEYRALMTELRILIHLGPHLNIVNLLGACTTKEGPLMVIVEYCRHGNLSNYLRGLRHCYTGGRSDDTSKQEIKKQRLMSDDSADDGAFSGTDETDRSSWITDKRGSRASYLSGTGSLTSHEGDIRSHTRLSSGCEDSRMNLEKHHEANDDGDEKGKEQKDQLTLTDLLSYSLQVARGMEFLASKKCIHRDLAARNVLLSDYQVVKICDFGLARDIYKDPDYVRSGGDARLPIKWMAPESIFDKVYSNKSDVWSFGVLLWEIFTLGGSPYPGLQMDEDFCNKLRRGVRMGKPEHATDSVYSAMLGCWDNNPEDRPTFTKLCEEISDVLQEEAGHEYLDVLKIFEKEAEGKETLRGLRLYETPQETFTEGKNKMEEETSATINYTFVKVEDKENEETADETCEEISIVCDTVEANEIEENTYDDDIDEHNDPISDPQACVVLMDQDQPPLYEDVIASRIQDLN
The following text describes a protein:
Function:
Is involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MAETNVIKVKVHGMWASPWVRRVTIALKIKGIPYEYIEEDLKNKSQLLLQYNPVKKLVPVLVHEGRPIPESLIILEYIDEIWNNSPKLFPHDPYQRAEVRFWADFINLQVFEKLRDVVKARNDGEEEKIIKEIQENMSKLEANVKDLYSGATHVNGEIMEILDILMITLLPIINGVEESISVKFIHPEKFPLAFSWMKSGEAVAVVQESAPNHENLVKFLRKLRQLFRKM
The following text describes a protein:
Function:
Involved in the import of activated long-chain fatty acids from the cytosol to the peroxisomal matrix.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MISTASAFYQKHRVNLLRSSYIILLLATLYNSNSSSSNNKTDKKDSESTVLENKKIEEGKETAVDREEDESSKEELTIVSKHSTDSEDGAIIIDKESKTNHKGGERKGKVDFLFKLLLHDKKCLILFITQAILLNIRTLLSLRVATLDGQLVSTLVRAQYANFTKILLGKWMILGIPASFINSLISYTTKLCAVTINRKVSDFLLSKYLSNHHTFYSVASAESVSEIQDNLTKDIYTFSMNSSLLLNQLLKPMLDLILCSFKLLTSNTSVMGEGTLALGLIVYASNSLLKLIQPNFTRLTMASASLESWFRSLHSNLHSSNEEIALLRGQKRELENVDYSFYRLVLFLNREIKARAIYDVATAFVIKYTWGAAGLVLCSIPIFFKNKPSEDTLQLKEPGNDMTADFITNRRLLVTASSSIGRFVELKRNIQQLRGIRLRLNKFNDLLDANKGDDEKEPRDERCIVEYDDSRIKFENIPLITPANQVLVPELSFDLKHGNHLLIIGPNGCGKSSLFRILGGLWPIRATPNKNHQSKLIMPRRTVDRDCAIFYLPQRPYMGNRSTFREQIIYPDSIEQFKERYHNDYDLGDADLIKILQLLDLEDLVTENMSLLLAQRTSKNDSQQLSTEDNQSPCAIKVRDAFSIVRNWSEELTIGVQQRLAMARMYYHKPKFAVLDECTSAVAPEMEQRMYENAQNFGISLISVCHRTSLWHFHNYLLKFDGKGGYQFGPFNPKERLCNEEKLLELNAILDQQVPLWERKLKDLTIAKESNIIRKSETNLNLFEKIEDPKTSKSNALFNANKGQRITSPTGQETSKRLPLFSQPSSSASSNLLRNNKSLNKKVKTKKEEGKER
The following text describes a protein:
Function:
High-affinity transporter for adenine.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNNDNTDYVSNESGTLSRLFKLPQHGTTVRTELIAGMTTFLTMVYIVFVNPQILGAAQMDPKVVFVTTCLIAGIGSIAMGIFANLPVALAPAMGLNAFFAFVVVGAMGISWQTGMGAIFWGAVGLFLLTLFRIRYWMISNIPLSLRIGITSGIGLFIALMGLKNTGVIVANKDTLVMIGDLSSHGVLLGILGFFIITVLSSRHFHAAVLVSIVVTSCCGLFFGDVHFSGVYSIPPDISGVIGEVDLSGALTLELAGIIFSFMLINLFDSSGTLIGVTDKAGLIDGNGKFPNMNKALYVDSVSSVAGAFIGTSSVTAYIESTSGVAVGGRTGLTAVVVGVMFLLVMFFSPLVAIVPPYATAGALIFVGVLMTSSLARVNWDDFTESVPAFITTVMMPFTFSITEGIALGFMSYCIMKVCTGRWRDLNLCVVVVAALFALKIILVD
The following text describes a protein:
Function:
Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein stk3/mst2 and stk4/mst1, in complex with its regulatory protein sav1, phosphorylates and activates lats1/2 in complex with its regulatory protein mob1, which in turn phosphorylates and inactivates yap1 oncoprotein and wwtr1/taz. Phosphorylation of yap1 by lats2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration.
Subcellular Localization:
Cytoplasm. Nucleus. Note=The caspase-cleaved form cycles between nucleus and cytoplasm.
Sequence:
MEHSVPKNKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPEHWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIVGAKPVSILRDLITEAMDMKAKRQQEQQRELEEDDENSEEEVEVDSHTMVKSGSESAGTMRATGTMSDGAQTMIEHGSTMLESNLGTMVINSDDEEEEEDLGSMRRNPTSQQIQRPSFMDYFDKQDSNKAQEGFNHNQQDPCLISKTAFPDNWKVPQDGDFDFLKNLDFEELQMRLTALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQNF
The following text describes a protein:
Function:
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
Subcellular Localization:
Mitochondrion matrix. Nucleus.
Sequence:
MSSRVSFIQARRYAKVLNSNLINILKTMPKEKTHIPEAQKQRRKIKEKFSKYSPGRVTLQVLGTGAEGAPRSLYVFSDQSRYLFNCGEGTQRLAHEHKMKLAKLEHIFITRPTWANIGGLPGAALTIQDVGVPEITLHGPQGLEEIFIATRRFIVIKDLDIKMAQCDENTTFEDNVLKVKYVPLKRSGNSSPISEPKNSNLGQMQEDNIDYYAHEHSGRRKSPPKISESKLLQQKNKPTNFSMAYICQLQPRPGALLLDKCVSFGVPPGPLLGQLKSGHDVTLVNGKVVKASDVCEPDDPGPVFIVLECPSEEYLDSLIDCEEFKKHQETATKDEDLAHTVVHFTPQKIINHPRYKEWVDKFSPSTHHLILNDSNTCMGSSAVHRIQYKLNLLSDDIFPLLGDKGTQTIDDQVTEPPQPKKIKPDSPSLPIDQLSVKSRPASPTDPNIYTNTLFNYHLRPKKACDRSNELKLVPSQFIDETMAIENFPSVLHEVTQQMAQKRRHLTVRDFPRLLFLGTGSSIPNKTRNTSGMLLEIDENTSIVIDCGEGTVGQIIRFYGQDKANAELAKIRAVYISHLHADHHLGLIGVLQGRQRAMQKLEKGAQPLFLLAPKQIMWWLNFYDRCFEKISEEFVLVPNGELFFNNHELDQLLEKQLLEGLQMRDISTCLVKHCPNAFGVSFVHQNGYKITYSGDTMPSENLVQLGKTSDLLIHEATMEDELAAEAVIKMHSTTSQAIEIGRQMEAKYTLLTHFSQRYAKLPRFNENFSDNVGIAFDNMRVKLDELPLIPLLYPALKLMFVEYYEEMEQKAAKRQMKIEREKAQQFVT
The following text describes a protein:
Function:
Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce iron cations Fe(3+) into Fe(2+) in the lumen of the late endosome and lysosome. Reduced iron can then be extruded from the late endosome and lysosome to the cytoplasm by divalent metal-specific transporters. It is therefore most probably involved in endosomal and lysosomal cellular iron homeostasis.
Subcellular Localization:
Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Sequence:
MARCQGDAPCGPDGGTGSAALAAPALSSVGGPAGGARLPAARRERPRARKTSTPRVPRPRADVGGGRRRGRSRSEMATGRFFVFSLALGALGTLCVLLTIYWLQHWRGGFSLGRSDAIFNWHPVLMVAGMVVLYGAASLVYRLPQSWVGSKLPWKLLHAALHLTAFVLVVLALLVVFTYHRWKKITNLYSLHSWLGITTVFLYACQWLFGFAIFLLPWAPVWVRSLLKPIHVFFGASILSLAIASVLSGINEKLFFCLNNQTHYSGLPVEARFANVTGMLVVVFGLLVLYVLLASPWKPPEPGVLSDRQPLLLERE
The following text describes a protein:
Function:
Catalyzes the NADH-dependent reduction of methylglyoxal (2-oxopropanal) in vitro. It is not known if this activity has physiological significance. Cannot use NADPH as a cosubstrate. Seems to play some role in intestinal colonization.
Sequence:
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKSEGKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARANKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREMAEALER
The following text describes a protein:
Function:
[Isoform 1]: Involved in resistance to abiotic stress; [Isoform 2]: Confers resistance to heavy metal ions (e.g. cadmium (CdCl(2)) and copper (CuCl(2))) by chelating them at the plasma membrane of root cells, thus stopping their entry and reducing their accumulation.
Subcellular Localization:
[Isoform 1]: Cell membrane; Single-pass membrane protein. Nucleus; [Isoform 2]: Cell membrane; Single-pass membrane protein. Secreted, cell wall.
Sequence:
MTMSRNGKTNKAAYSQRFTRCSVAVAATRSASVVAAAFDFYICIIISTLLSLIVSLASQLLF
The following text describes a protein:
Function:
Involved in proteolytic processing of BAG6 and plant basal immunity.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MEPDLHDQQQQQRVHSVVIITLPPSDDPSQGKTISAFTLTDHDYPLEIPPEDNPNPSFQPDPLHRNQQSRLLFSDLSMNSPRLVLGLLGISLLAVAFYASVFPNSVQMFRVSPDERNRDDDDNLRETASFVFPVYHKLRAREFHERILEEDLGLENENFVESMDLELVNPVKVNDVLSTSAGSIDSSTTIFPVGGNVYPDGLYYTRILVGKPEDGQYYHLDIDTGSELTWIQCDAPCTSCAKGANQLYKPRKDNLVRSSEAFCVEVQRNQLTEHCENCHQCDYEIEYADHSYSMGVLTKDKFHLKLHNGSLAESDIVFGCGYDQQGLLLNTLLKTDGILGLSRAKISLPSQLASRGIISNVVGHCLASDLNGEGYIFMGSDLVPSHGMTWVPMLHDSRLDAYQMQVTKMSYGQGMLSLDGENGRVGKVLFDTGSSYTYFPNQAYSQLVTSLQEVSGLELTRDDSDETLPICWRAKTNFPFSSLSDVKKFFRPITLQIGSKWLIISRKLLIQPEDYLIISNKGNVCLGILDGSSVHDGSTIILGDISMRGHLIVYDNVKRRIGWMKSDCVRPREIDHNVPFFQG
The following text describes a protein:
Function:
Transcription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae).
Subcellular Localization:
Nucleus.
Sequence:
MSEKEEAPSTSKSTGAPSRPTLSLPPRPFSEMFFNGGVGFSPGPMTLVSNMFPDSDEFRSFSQLLAGAMSSPATAAAAAAAATASDYQRLGEGTNSSSGDVDPRFKQNRPTGLMISQSQSPSMFTVPPGLSPAMLLDSPSFLGLFSPVQGSYGMTHQQALAQVTAQAVQANANMQPQTEYPPPSQVQSFSSGQAQIPTSAPLPAQRETSDVTIIEHRSQQPLNVDKPADDGYNWRKYGQKQVKGSEFPRSYYKCTNPGCPVKKKVERSLDGQVTEIIYKGQHNHEPPQNTKRGNKDNTANINGSSINNNRGSSELGASQFQTNSSNKTKREQHEAVSQATTTEHLSEASDGEEVGNGETDVREKDENEPDPKRRSTEVRISEPAPAASHRTVTEPRIIVQTTSEVDLLDDGYRWRKYGQKVVKGNPYPRSYYKCTTPGCGVRKHVERAATDPKAVVTTYEGKHNHDLPAAKSSSHAAAAAQLRPDNRPGGLANLNQQQQQQPVARLRLKEEQTT
The following text describes a protein:
Function:
Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer. Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.
Sequence:
MSGSLGRVSAALLHLGRGVLLRGPARRTWSQTTERSSSSGGSGSGSTEYLDKLVKKDKVVVFLKGTPEHPQCGFSNAVVQILRLHGLTNYAAYNVLEDPALRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIRSALLDAKKDQDSKDFKTQKET
The following text describes a protein:
Function:
Catalyzes the conversion of L-arginine into 2-ketoarginine via transamination. L-arginine is the best substrate, but it can also use L-lysine, L-methionine, L-leucine, ornithine and L-glutamine, which indicates that it may have a broader physiological function in amino acid catabolism.
Sequence:
MRYSDFTQRIAGDGAAAWDIHYRALARVEQGEEILLLSVGDPDFDTPAPIVQAAIDSLLAGNTHYADVRGKRALRQRIAERHRRRSGQAVDAEQVVVLAGAQCALYAVVQCLLNPGDEVIVAEPMYVTYEAVFGACGARVVPVPVRSENGFRVQAEEVAALITPRTRAMALNSPHNPSGASLPRATWEALAELCMAHDLWMISDEVYSELLFDGEHVSPASLPGMADRTATLNSLSKSHAMTGWRVGWVVGPAALCAHLENLALCMLYGSPEFIQDAACTALEAPLPELEAMREAYRRRRDLVIECLADSPGLRPLRPDGGMFVMVDIRPTGLSAQAFADRLLDRHGVSVLAGEAFGPSAAGHIRLGLVLGAEPLREACRRIALCAAELLGQA
The following text describes a protein:
Function:
Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Note=Localizes to microtubule and actin cytoskeletons.
Domain:
The GAR domain modulates the binding strength to each cytoskeletal network.
Sequence:
MQPAIQVWFGEDLPLSPRSPLTPRHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTSGPEDSISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK
The following text describes a protein:
Function:
Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNENCIYFCGSIRGGRDDAEIYRQLISHLQTYGKVLTEHIGSTEVNEKGIIKEDVGRTDKEIHDRDIEWLEYAKVVVAEVTQPSLGVGYELGRAVAMGKQILCLFRPSPDKRLSAMIEGAKNGDNFRVVHYNNVEDGCLAISSYMKSLCNV
The following text describes a protein:
Function:
Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MERPVWFRWLRVYAIGFGIIGAGVLLFKYTTPTDEELIAALSPELRQQYERERKLRQAEQQELMRIVKQTAASETPVWNTGPIKSPWERKGVSAESREQFQQVKAEQVQREELQRIREELETIRQQSANKTQEIASKKSWWPW