lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the pid-1 and tost-1 variants of the PETISCO complexes, which have roles in the biogenesis of a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs) and embryogenesis, respectively. Within the pid-1 variant of the PETISCO complex may stabilize 21U-RNA precursor molecules. Promotes the biogenesis of 21U-RNAs. Required for chromosome segregation and cell division in early embryos.
Subcellular Localization:
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Dispersedly distributes throughout the cytoplasm in early embryos. During early embryogenesis, localizes to the nucleus at prophase of cell division, and remains in the cytosol at interphase in 2- and 4-cell embryos. Localizes to puncta in the perinuclear region in the germline syncytium.
Sequence:
MVAHQKADFKSKWAMVVTVNNLNDKKRADLREFSEWFIETLRLEGAFIGHYFNYEAAPVTIVETLPGNFDSCTNAYQKIHKEHPQVVLVVHILPQSQSNEYEWMKVLASRYGFVRQGLLYDNCANRFQNVETDQNSVFRNMCQWIYRSGTAIVRNEGNACGILHGKDPKPTFDKVLFNSEDIKDSVFKVLHAEEEPRGADQENMLKISGYPGMLNTFGIAQLLTPYRVNGITITGAQSAVVALENKFQVYQAVQDFNGKKLDRNHKLQVSSLVVSSPAVPLEWPSLKKSKKLVEQVGKPIRLSKVSS
The following text describes a protein:
Function:
Facilitates RNA binding of SUB2 and likely plays a role in mRNA export. Suppressor of the transcriptional defect of HPR1 by overexpression.
Miscellaneous:
MISCELLANEOUS: Present with 6580 molecules/cell in log phase SD medium.
Sequence:
MADYSSLTVVQLKDLLTKRNLSVGGLKNELVQRLIKDDEESKGESEVSPQEQNQEQGSEPAAIEEPASQNITEKKEVSSEPKETNEPKEENKDVQKPSDGPSATASENEQAAASTAAPALSPEEIKAKALDLLNKKLHRANKFGQDQADIDSLQRQINRVEKFGVDLNSKLAEELGLVSRKNEPESGNNGKFKNRNKNANNRSRVSKNRRGNRSGYRR
The following text describes a protein:
Function:
Nucleotidyltransferase involved in the post-translational modification of proteins. It can catalyze the addition of adenosine monophosphate (AMP) or uridine monophosphate (UMP) to a protein, resulting in modifications known as AMPylation and UMPylation.
Sequence:
MSVWNAVHLSRRFAALPQAFYTPVHPQPLQNVRWGMWNSRLAQQFGLPEAPNDELLLSLSGQQLPADFSPVAMKYAGHQFGVYNPDLGDGRGLLLAEMATKQGEVFDIHLKGAGLTPYSRMGDGRAVLRSSLREYLCSEAMAGLGIATTRALALMSSETPVYREREERGALLVRLAHTHVRFGHFEHFFYTDQHANLKLLADKVIEWHFPDCVQTSKPYAAWFSQVVERTALMIAQWQAYGFNHGVMNTDNMSILGETFDYGPFAFLDDYDPNFICNHSDYQGRYAFDQQPRIGLWNLSALAHALSPLIDKDDLEAALGSYSERLNLHFSRLMRAKLGLATQQEGDGELFADFFALLANNHTDYTRFLRELSCLDRQGNEAVIDLVLDREAAKTWLTRYLERAARELGQEGRPISTRERCQAMRQVNPKYILRNYLAQQAIEFAERGDFEEMQRLATVLASPYAEHPEFERYAKLPPEWGKKLEISCSS
The following text describes a protein:
Function:
Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
Subcellular Localization:
Cytoplasm.
Sequence:
MNHLNKLMERLGHQFNNLELLKIALTHCSSGADNNERLEFLGDSVLGFIIASELYQRRPQAREGDLSRMRASMVNGDELAQMSTKLGINEYLQLGVGEQKSGGKRRRSILADALEAIVGAIYIDAGLETCRRCVLNWYGERVDDLSKLSPKKDAKSLLQEWLQARRLPLPTYEVKITGEAHAQTFTVNCYVKGLPHKTEGVNTTRRRAEQIAAKRFLELLDDGKGDGITERDQ
The following text describes a protein:
Function:
Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPLSFEGTFKAKRNVNLGGKRVSNDRAQLLRKAAMERKNREEERKAENNSVAVQSLSRGFLARRKFKQDFRERWIYKYTKSGRTSIRFNTLEDIKCSISLLVLFAEPDIDLPFVSQVAHNILVWLENLIPLSNGMDDTPKSHLKVKILKVQETLSNSNDSWLWQRFSSLLLNCLVSSINSHRIEGTDTSAETSLLHCLAYVAPYLKSSELSTYYDSVMTFYAQIYPKQNMTNLEDIMSLSLLTPVSSKTDENANSSSAFLFHVLASDCFSSIENCIPPDLIIDKVFSSSLQLSEEACISSLLNLGMIKVFSLAGNCLHLLHTEYKNSSLWKFCSYILDALYVFSGESVNSRIQVVSDVDDDEDDENAFSQNYYSHLQMVAKHFSKNYANQSGIVQRSFAECISSTFITKAFKLVSSNTLQAMSHFYATMIKLFPSNRTSILMYISLVETNEGSLTRSFSRFSWDMFSESPVYQLFHKKFDVQNVLKNDSGYWFQLQLLIDVYSRMLFTMIDDEFHNDKQNPLYPVMAEFCTVLKNLVLGLYWDVQAAKDVDCKSVVDISQLRVSSTSLLQQLYRINSRKQFLPEDFFLMSEYFNLNEFEANALQESELASHAEAEINITYKFDNFSESRPRLNILNNCSFFLPFHFRIHLLQQLLLLDKQANGYAQPFGHLKHAVIRRNRIFDDGFDAFYNFGKLLKGPIRITFVDEHGVVEEGIDGGGLTKEFLTSICKTVFDINYGLFSETKAHLLYPNTHAYAQDVERLRCYEFLGMLIGKCIYEGIQIDAAFASFFVAKWLGHPSYFDDLTSLDPNLYEGLVFLKNYDGDVENDMALNFTVVHEEFGVRNVIDLIPNGSNISVTNENRLQYIHLVSNYYLNARLSRQCRAFTNGFTQIIDPHWLAMFHESEIQILVGGDPVPIDIDDLRRHTVYAGGYEPNSPTIVLFWEVLREFEEEDKRSFVKFVTSVARPPILGFKALMPSFCIRVNGEDETRLPTASTCVNLLKLPMYSTKQTLRDKLLTAVRSGVGFGFS
The following text describes a protein:
Function:
ATP-dependent RNA helicase that may play a role in various aspects of RNA metabolism including pre-mRNA splicing or ribosomal RNA production. Also acts as a viral restriction factor and promotes the activation of the NF-kappa-B and IRF3 signaling pathways following its stimulation with viral RNA or infection with RNA and DNA viruses. For instance, decreases vaccinia virus, herpes simplex virus, Zika virus or dengue virus replication during the early stage of infection. Mechanistically, acts via the adapter TICAM1 and independently of the DDX1-DDX21-DHX36 helicase complex to induce the production of interferon-beta.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MPGKLLWGDIMELEAPLEESESQRKERQKNDRRKSRHHSESEERTETRENGVTDDLDAPKPKKAKTREKLNGDTKEGLRFSDEFSPSHKSRRKDLPNGDVDEYEKRSKRVSSSENSHKSSDKADETLTREQKEGAFSNFSISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLNVACFYGGTSYQSQINQIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKSDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVENAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICVCFYQPRERGQLRYVEQKAGITFKRVGVPSTMDLVKSKSMDAIRSLASVSYAAVDFFRPSAQRLIEEKGAVDALAAALAHISGASSFEPRSLITSDKGFVTMTLESPEEIQDVSCAWKELNRKLSSNAVSQVTRMCLLKGNMGVCFDVPTSESERLQAEWHDSDWILSVPAKLPEIEEYYDGNTSSNPRQRSGWSGGRSGRSGRSGGRSGGRSGRQSRQGSRSGSRQDGRRRSGNRNRSRSGGHKRSFD
The following text describes a protein:
Function:
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Domain:
Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
Sequence:
MRLLPRLLLLLLLVFPATFLLRGGSGGSVAVAQDLTEDEETVEDSIIEDEDDEAEVEEDEPTDLAEDKEEEDVSGEPEASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQTVTIIEREDGLDGETIFMYMFLAGLGLLVVVGLHQLLESRKRKRPIQKVEMGTASQNDVDMSWIPQETLNQINAGGGRHTDAVLRPLLQLCVHGLRARAAHSSRLLQETPGRAAPGDRPSFLRCFAICET
The following text describes a protein:
Function:
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
Subcellular Localization:
Nucleus.
Sequence:
MVRIYVRNKGRYDPKTSESPLPFLDVDNPGDVLIKHVRETVKRRINCKLDELYYNNQLLDEDRSVAYSNLQDGTILESCSNPFWAACMYIRLRAVEQEAANNPTDQKKQRWTHQSIVNRAAALGVLFNSNSFERHQPPHLPTLQDLWTCLQTNGRKPVHMSEFTRTALQELQEEFQNIDLHRRDPLASFVHRHAVKLGFRDPNAPGPGDGPVNDGPGSAGPAEQGGNAVGARGNNNKRNGGRRRQTRPRPCDDCEAENATKYCAQCEGGLVLCQPCCDRLHQGRARRHHNIQDVEEAPKAAKSYTPKAYKAPFAMLVALFKGLSQVPQIMSMTADEIKSRAQVFTDTDLSDRAAGKFFGGFDNMQNTLQINGFVQREAGENARFSLLQPGRALAQKCTEFHQAVEELLDMNRVPKVPQLGGSQCGTRRVCLLVDSKEPLCERMTALAHRQGVAAQIRDLPVGDFLWILLPPATGVDYAAVRPDDEQVLPHIVERKTWDDLQHSLSTRRFRNQVEAMKRCGLRDLFYLVEGHPSDMRARPSKEQIQYFENQLLNLEMTDGFLVNRTGTWLKTAQWLLQLTAMAADMHNTGTSGGLITYAEYSTRASSKNFAAPEARPRADYLGVHRWSADKLVDIVFREFHDETNFSDAAKTDLPDIPPTQRSRGSRPLLILHDLEVYNKNSQKFKDRALAEYLNQQAGNRTVREIVDTMLGASVRELIHFDVFCYWQLWLQVHLGCHVKRTETPEETQRLENMYRQNRNNAAPNEALFLDNFLNHNDDDNDDDDDGDYRGGAPLRGRGRGRRAQGRGRGNNRRAPQLPPNNRRVAGSTTVGRRKPSQGRQQDRSNVEMGNDPPLPDLTADIGGMVNARMGGDEGRRLGSLSTDDFAPDSQNEDLMIQQALELSKAETLPATEKYGDADKTEDVNREEEDQLAEALRLSLMEHERQTSTMQEHRIVPDKQQDFENTSNNMSTESLDETDPIEIIDSQEVNETVAETEGSAGKDISLEEPIEIIDSQDTVESVVEEKDYPIEISDDSQNTGASNEAVQDARALELTSSSSDTQEEELSSNVTEKEKPNKTNSEKAHCSIEQVISTTNGFNVEDTSTQESAINKESDVSDSRLFEKSLDLRKSTCEGGAKLEQMQQKSKNDVDVPFGMLKDTTTQSQNGQDAMPFDSNSDKMLNSSDDRSHTCNKEKEDSTTENVEMDPDLALAIRLSQEEAKMAQKRYAEACVEKRVTRSKAKSNASPAATHAVDKPNISKVKREDEPCLENDTGVEEELDPDLALALKLSKDEFIASQKQDEELIRQKASQGQQSNNHTVTNTSVKDSEKVSNKGRQGRNASGQNNSDILSCAISTEQVLQDKPFSFVENSVQEEEFIEENFGQALQPSRQKSDSPEDNENKLKELAASLSGNTGTLNRNESLQDFQDFESQIDDTDQDLCLALKLSEKENSSTASIAGNCGGKNLPMSQKDKDTKQNLQKDFELAVRVAFQEKVDCDRSCSKLSEMDTSRVKEERMDEQCSHDKDFELAKKLQEDLNSKLSEMDTSQVKKEEMKEQCSNDKDLELARKLQEDMNQEALQPENSKSTEAVKVLGGVKSSNAKRKLDLHYEKDLKLARQLEAELNGKPAEVVNSPKRIKVDVDYERDLALARQLEKEKNSSQTQYEKDLELARKLSEELNSKGSGTSSNSSAVGSPNLKRGLTPNSSSSETSEGPAVFRERRRERARSAQQLEDYRRLQAQHYRTSSVGATAAASKSTPASSPCRVSQYASGPPAAETFTMDDDDDDDLPDIPPGLPPHDANPGTSNATWTPPTHQGPSSSSASTSRPSTSDRSDTPACSGTPSTSDGAQAGTPRQNTTTCGACGQQGHNRSSRRCPRYFCEEEVRRRQAQAERRQAKAEAEERDFRSKLGRLEREREESARVRSQLRRQFEEMDRRMREREEDAQAVIQHLDKGRKKRKK
The following text describes a protein:
Function:
Involved in lysis inhibition. Senses superinfections and inhibits the holin, thereby delaying the host cell lysis timing. The genomic DNA from the superinfecting phage bound to the complex holin-antiholin probably serves as a signal for the lysis inhibition and blocks the holin multimerization.
Subcellular Localization:
Host periplasm.
Sequence:
MALKATALFAMLGLSFVLSPSIEANVDPHFDKFMESGIRHVYMLFENKSVESSEQFYSFMRTTYKNDPCSSDFECIERGAEMAQSYARIMNIKLETE
The following text describes a protein:
Function:
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
Sequence:
MNFAEVLLERKLLLIGSFVLTSGKVSPYYLDLRPLPNYPEFYDIVNQAIKKAKDIPHDIIVGIATGGVPLSAFIACNLKEPMGYIRIEKKGHGTNRTLELDVKGKRVLLVDDVATTGVSIEKATLEILNGGGKVSDALVIIDRQEGASQRLEKLGVKLHSLFKISEILDELLKSDKLKDNEKKSILDYLVKNVEK
The following text describes a protein:
Function:
Intracellular mono-ADP-ribosyltransferase that plays a role in different processes, such as protein translation and unfolded protein response (UPR), through the mono-ADP-ribosylation of proteins involved in those processes. Acts as an inhibitor of protein translation by catalyzing mono-ADP-ribosylation of ribosomal subunits, such as RPL14 and RPS6, thereby inhibiting polysome assembly and mRNA loading. Mono-ADP-ribosylation of ribosomal subunits is promoted by NMNAT2. Involved in the unfolded protein response (UPR) by ADP-ribosylating and activating EIF2AK3 and ERN1, two important UPR effectors. May also mediate mono-ADP-ribosylation of karyopherin KPNB1 a nuclear import factor. May not modify proteins on arginine or cysteine residues compared to other mono-ADP-ribosyltransferases.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MAEELLRNVREKLEGDLLAADLQLSLFAAALLSYRHDTVLRPFPPGFARQNDEKDFPALKSVWRRLPGAKDLLQSSGATSDPQTLQLVNWVLETRNFCLRSCESTEYKEVQRLTGYSSTNIPPPSHIFEVVHSETTDARFEETRQDRSLLYAFHGSRLDNFYSILHNGLHAHLNKNSLFGEGTYLSGDLGVSIIYSHKGQGWDRSMLGETMSCVAVCEVIMDPKYVKSKVEEENGRAKNKDKQEVPEKYYIVSNNELLRVKYVLVYAEKKVQQRVQTPSFFQRHKFFVLMSLYVVVLAVIGAANSPNLQYYLRRLYK
The following text describes a protein:
Function:
Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin.
Subcellular Localization:
Nucleus.
Sequence:
MMIPIAIRWQGKKYDLEIEPNETGSTLKHQLYSLTQVPPERQKVIVKGGQLKDDVLLGSVGIKPNATLLMMGTAGELPTAMPIPAVESVEQEESEDDGYPSGLINLGNTCYMNSTVQMLRAIPELSDAVSQFNSSGGLVAEYRTLLNSMQSNAPVTPMRFLQSLRMEYPQFAEMSRETGGYAQQDAEECWSFLLSVLQRSLSSEWVQKNMAGKLLSTMKCDENEVQEQPSISHDTFLSLPCHISMHTSYMTQGILEGLTQKISKHSDVLNRDAMYSKISRISRLPNYLTVNFVRFYWKASIGKKAKILRKVKFPFELDAVEFCTPELSQKLIPVRDKLREIEKNDEEHERAAKRIKIQPSEDEKEAEAECRLTQVATCQSLVDPELADDEGANPTGLYDLVGVLSHAGASASSGHYQAWIRNSNNRAEWFRFNDAKVSIVPAEKIETLDGGGEADSAYILLYKAKDIA
The following text describes a protein:
Function:
Positive regulator of ferroptosis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKYLIEVIGETFLSISDPIDHRHWFLSKEQHAYEFIFMNLFYLVVIFIGINLNKKREYENQRKPKPIPEKDYPSLLNKIVAIILAINVFLNLIYKCLRGWRVVFFMLQPCHIVSTIYCYCLLTNNYQFGRKVFKISIYYILVTIAALVAPDLADLTLPFECYNFFIQHYALLIAPFLLQAYRYNIEFELPYALISQGLFGISHFFVFEIFCFISGTNINYMLFPPPLGEFSYLTQESYRVGIAFILFILALGIGRLVILIGSKIRSTFLLKNKSK
The following text describes a protein:
Function:
May contribute to the structure and reorganization of filopodia and pseudopodia accompanying cell movements.
Sequence:
MAETKVAPNLTGIEQTKAGQSFTEKLSAEAMEFFCNVAKLPFSQQAVHFLNAYWAEVSKEAEFIYSVGWETIKYADMHCKGIQLVFKYDEGNDLDFDIALYFYEQLCKFCEDPKNKNYATTYPISQPQMLTALKRKQELREKVDVNFDGRVSFLEYLLYQYKDFANPADFCTRSMNHDEHPEIKKARLALEEVNKRIRAYEEEKARLTEESKIPGVKGLGATNMLAQIDSGPLKEQLNFALISAEAAVRTASKKYGGAAYSGGAGDAGAGSSAGAIWWMNRDLEEKKKRYGPQKK
The following text describes a protein:
Function:
Potential transporter for phosphate.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAVMDPWLLITIIVGFGMAWAIGANDAANSMSTAVGAKAITPKQAVLIAGVLEFTGAYFFGKSVTETIRKGILYPDRITDPTVLIYGSVAALLAATIWLVIATKFGLPVSTTHSIIGGIVGYGIVYAGFSIVNWGKMTQVVLSWILSPIIGAIMAFLVFKALTKSIFERKDPVRSSKIWSPFWIGLAFVVIGTMFYIKVLHGKSLKTGVLFYGIPAGLVVFLILFLTLRVKFPSSDPFIGVESIFRRVQVITSGYVALAHGANDVANAIGPVAAVYAVATMGMAGMKVPVPRWILAMGGLGIAIGVATYGYRVMETVGKKITELTNTRGFTIDFSAATVVLVASWLGLPISTTHVVVGAVIGVGLARGVKAINKDIVRDIIISWFVTVPVAALISAFLFKILMIVG
The following text describes a protein:
Function:
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB subunit has 5' -> 3' nuclease activity but not helicase activity.
Miscellaneous:
MISCELLANEOUS: Despite having conserved helicase domains, this subunit does not have helicase activity.
Sequence:
MSLRFVIGRAGSGKSTLCLREVQEELKQRPRGKTILYLVPEQMTFQTQQALIGSEDVRGSIRAQVFSFSRLAWKVLQEVGGASRLHIDEAGVHMLLRKIVESRKDGLSVFQKAAEQNGFFEHLGSMIAEFKRYNVTPSNVYEMWQQLDAHSSSAEQKLLANKVYDLQLLYDDFERALIGKYLDSEDYLQLLVEKLPQSEYVNGAEIYIDGFHSFSPQELEIVRQLMICGARVTITLTIDEKTLAQPVNELDLFYETTLTYEKIKQVAREEKIEIEKTIPLMEQPRFHSPALAHLEAHYEARPNEKFNGEASVTISTAANLRAEVEGVAREIRKLVADEKYRYRDIAVLLRNGESYYDVMRTLFTDYNIPHFIDEKRPMSHHPLVECIRSALEIISGNWRYDAVFRCVKTELLYPLDVRKEAMREEMDEFENYCLAYGVQGKRWTAEDPWMYRRYRSLDDTNGMITDSEREMEEKINRLRDVVRTPVIRMQKRLKRAGTVMQMCEAVYLFLEELDVPKKLEELRIRAEESGDFLFATDHEQVWEEVMSLLDTFVEMLGEEKMSLSMFTDVMSTGLEALQFANIPPSLDQVLIANIDHSRLSDVRATFIIGVNEGVIPVAPMDEGMLSDEEREVLGAAGIELAPTTRQTLLEEQFVMYQMVTRASEKLYISCPLADEEGKTLLASSFIKKIKRMFPNVKDSFISNDVNDLSRSEQISYVATPEVTLSYVMQHLLTWKRYGFEGNLDFWWDVYNFYVTSDEWKQKSSRVLSSLFYRNRAKKLSTAVSRDLYGDIIKGSVSRMELFNRCAYAHFAQHGLSLRERDIFKLDAPDIGELFHAALKKIADKLLRENRTWADLSIKECEHLSVLVIEEIAPLLQRQILLSSNRHFYLKQKLQQIIFRTSIILREHAKSSGFVPVDLEVPFGMGGTGSLPPMEFSLPNGVKMEVVGRIDRVDKAEDENGTFLRIIDYKSSSKALDLTEVYYGLALQMLTYLDVVTSNAQTWMKKGHAASPAGVLYFHIHNPIVEMKGDATEAEIEKEILKKFKMKGLVLGDADVVRLMDNKLSTGSSDIISAGLKKDGSFSARSSIASEQEFNVLQKYVHHTFENIGKDITEGVIDIAPYKMGNKAACTFCNFKSVCQFDESLEDNQFRSLKDMKDSEAMEKIREEVGGE
The following text describes a protein:
Function:
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
Sequence:
MGELEVPERELEYFATSARAGRRNALPEIEVEINDQDAAKLAERMSDMTAHCEETADNQNQPGPSQPKQGNS
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Lipid-anchor.
Sequence:
MGGSSSRKVSFGVGEGEKIHVLRGVRLSDDLINRMKDSSYASYPAANPPLYPPEGKAQLPRTEPRLPVAEGDQSPSKVEDQLYKRYEEERGMIREELFRLAKREREMAREHRNMFRQQKESCVNQEKQSNAEIYKLSSQQFHEAATQAESSIKPRSIEPVCGVLQSEILRCYRKNKEEVLKCSNLAKAYQQCVIAAREVRISPRVSRGISFDPLSEHHLCSFCAESAGHRAHFFWAPASGSPTERPGREKKSPFTDSASSWNLLKLGHLWFSPFLWSRAPRESSHLLTLSQRATMLLGMENLTSGQPPSPPHSGFSR
The following text describes a protein:
Function:
Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
Sequence:
MGAPSKSKDGKKKKEKKEGGGGGTDDARPPTIDCPKSAQPEGKGEGDKGLPNCVTFFPEVITYQPENKKQVRNIEVKNKGDRSIMFKMKSTSPGVYRMRPIHFILRPGESKIIKLSYKGCADGKAPNLKDRFTVVMAYPPGVESNVKLMWTQKAYIEKIADCTHRKYIKVHFDGYDVPDKNAKNQDDDKDEKEGEDEEEEEDEKDEKDKKKK
The following text describes a protein:
Function:
Sugar transporter involved in the transport of CMP-sialic acid from the cytoplasm into the Golgi. May transport important nucleotide sugars such as CMP-Kdo (2-keto-3-deoxy-D-manno-octulosonic acid) in physiological conditions.
Subcellular Localization:
Golgi apparatus membrane. Membrane; Multi-pass membrane protein.
Sequence:
MGSSSAPAAAAAAAPSRRKVALYLALLTLQYGAQPLISKRFVREDTIVTSLVLATEAAKVICAIILLIAEGSLKKQFSNWTLTGSLTASGLPAAIYALQNSLLQVSYKHLDSLTFSILNQTKLLWTAFFTFLILGQKQSSRQVLALALLIGAAVLLSVGESSSKGSKGGGSDYILLYGIIPVTVASVLSGLASSLCQWASQVKKHTSYMMTIEMSFIGSMCLLASTYRSPDGEAIRKYGFFHEWTFWTVQKLQWIFIDVWDPNHHSLPQIPVLMNAVGGILVGLVTTYAGGVRKGFVIVSALLVTALLQFIFDGKPPSLYCLIALPLVASSIFIYQKHPYVDRKKKD
The following text describes a protein:
Function:
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. May activate the TOR signaling cascade in response to amino acids (By similarity).
Sequence:
MEKVDEFLEYIKVSILDKSIVDTSLILSDRDGFVLGKIIDKSSSADNVIDNSLISTFSSATDQASKLHAGNNKSIVSFFEDRIIVHINVSNVILSIITDTESNVGLILGSQDDLIRSLTSLSNSIQSDIQDM
The following text describes a protein:
Function:
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
Sequence:
MRKEDKNSIIEQIAATVKEYGHFYLVDVTAMNATATSALRRDCFKSDIKLMVVKNTLLHKALESLEEDFSPLYGSLKGTTAVMFCNTANVPAKLIKDKAKDGIPGLKAAYAEESFYVGADQLDALVAIKSKNEVIADIVALLQSPAKNVISALQSGGNTLHGVLKTLGERPE
The following text describes a protein:
Function:
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Subcellular Localization:
Nucleus.
Sequence:
MLNRLGSAAIWPFFYSIRYEPNRSSSASKPLTPPSLVRVSFLPRSRSRQSRQRYSKHPGNHSLSFALTTASQNRPRSTVAMSSNADTAQAKSRSGRLPRKRFYRARAHSNPLSDSHFPIPISPADFDCSHHYPYFFPPGSGGRSDGDAPPRKVRFADIGCGFGGLLVGLSPLFPDTLMLGMELRDKVTEYVKERILALRASNPGHYENISVVRTNSMKYLPNYFEKGQLSKMFFLFPDPHFKEKNHRRRVISPQLLDEYAYALEVGGIIYTITDVEELGDWMRSCLEDHPLFGAVPEEELVLDPVVKLLSSATEEGQKVARNGGQTFRAVYRRIKLEEE
The following text describes a protein:
Function:
Positively mediates root hair elongation.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MEKDNDFKDPFLASTEEEELDPATQKALMEYLGVGSRASSLVSFSSTAVDIPPISGVGDFVREFRIESRKLWKLAGPAIFTTMSQYSLGAVTQVFAGHISTLALAAVSIENSVIAGFSFGIMLGMGSALETLCGQAFGAGKVSMLGVYLQRSWVILSVTALFLSLIYIFAAPILTFIGQTAAISAMAGIFSIYMIPQIFAYAINFPTAKFLQSQSKIMVMAGISGVVLVIHSFFTWLVMSRLHWGLPGLALVLNTSWWVIVVAQLVYIFNCTCGEAWSGFTWEAFHNLWGFVKLSLASAAMLCLEIWYFMALVLFAGYLKNAEVSVAALSICMNILGWAAMVAFGTNAAVSVRVSNELGASHPRTAKFSLVVAVILSTAIGMFIAAGLLFFRNEYPVLFVEDEEVRNVVRELTPMLAFCIVINNVQPVLSGVAVGAGWQAVVAYVNIACYYLFGVPFGLLLGFKLEYGVMGIWWGMVTGTFVQSIVLTWMICKTNWEKEASMAEERIKEWGGVPAEKETLLN
The following text describes a protein:
Function:
May have a transcription role in testis.
Subcellular Localization:
Nucleus.
Sequence:
MEAAADGPAETRSRVEKDSRRAIKDSPAKTQSPAQDTSIMLRNNADTGKVPALPEHKKKRKGYSPAESVKILRDWMYKHRFRAYPSEAEKRMLSKKTNLSLSQISNWFINARRRILPDMLQRRGNDPIVGHKTGKDAHATHLRSTDASVPAKSGPRGSDNVQSLPLRSSPKGQMSGEKIPEPGSAPSQKLTMIAQPKKKVKVSNITSLSSPEPVSTEEYADFSSFQLLVDAAVQRAAELELEKKQESNP
The following text describes a protein:
Function:
Can specifically bind site II elements in the promoter region of PP438/PNM1.
Subcellular Localization:
Nucleus.
Sequence:
MDLSDIRNNNNDTAAVATGGGARQLVDASLSIVPRSTPPEDSTLATTSSTATATTTKRSTKDRHTKVDGRGRRIRMPALCAARVFQLTRELGHKSDGETIEWLLQQAEPAIVAATGTGTIPANFSTLSVSLRSSGSTLSAPPSKSVPLYGALGLTHHQYDEQGGGGVFAAHTSPLLGFHHQLQHHQNQNQNQDPVETIPEGENFSRKRYRSVDLSKENDDRKQNENKSLKESETSGPTAAPMWAVAPPSRSGAGNTFWMLPVPTTAGNQMESSSNNNTAAGHRAPPMWPFVNSAGGGAGGGGGAATHFMAGTGFSFPMDQYRGSPLQLGSFLAQPQPTQNLGLSMPDSNLGMLAALNSAYSRGGNANANAEQANNAVEHQEKQQQSDHDDDSREENSNSSE
The following text describes a protein:
Function:
Involved in targeting GBSS1 to the starch granule. Was originally thought to be a carbohydrate-binding scaffold protein, but it has been shown that it is mainly found as a soluble protein and that interaction with GBSS1 is a pre-requisite for subsequent starch granule binding. Dissociation from starch as a function of pH, Mg(2+) concentration or redox state is not observed. Interacts primarily with amylopectin and is required for amylose synthesis.
Subcellular Localization:
Plastid, chloroplast stroma. Note=The vast majority of PTST is soluble and only a small amount is granule-bound. No localization to the starch granules in the absence of GBSS1.
Domain:
Contains a C-terminal (199-277) carbohydrate-binding domain (CBM).
Sequence:
MGCVPRIEFGCSSQSLTLSWNLRAWNLCRLNTISHFQKLPYPLVASTRKHYKNSLLLKRFLVGVGTEESSLSEDLLDESLSRPLTSDELKSLLIDTERSKLVKKLSEANQQNRFLKRQLKTQEHEITNIKTELALMELEVQALVKLAEEIANLGIPQGSRKISGKYIQSHLLSRLDAVQKKMKEQIKGVEAAQSKEVHVFWIGMAESVQVMGSFDGWSQREDLSPEYSALFTKFSTTLFLRPGRYEMKFLVDGEWQISPEFPTSGEGLMENNVLVVE
The following text describes a protein:
Function:
Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro). Binds to RNA. May participate in nuclear mRNA metabolism.
Subcellular Localization:
Nucleus.
Sequence:
MLRSVLFSFVRLPALATFCCHSRNMGNPRNHLPDRWTEYTSLGKRIPGTRFIAFKVPLKKIFNCRIESWQRFSSADLIRDIQAQDEELGLIIDLTCTTRYYSPEELPESLHYAKIFTVGHEVPSDETIFQFKSIVNQFLEENSSNDKLIGVHCTHGLNRTGYLVCRYLIDVLGMEPSDAIEKFNQSRGHCIERKNYLDDLMHGDVRSNAECDEPQLPRPKYQQKIPNVNNPSVPPCPPPHHRPDQPRFSRFGNPTDAPWIPESRPRFVHPPRHNMPRPMYNDPSMDYNSRRYPRDDDWQQLDQWNPHPYHYGNQQSRNPNGHQPPSRYSNGNQTPPRSANTPRGSASWRTEGNDSYRRHPARGMKTRKY
The following text describes a protein:
Function:
Involved in the early part of the secretory pathway.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type I membrane protein.
Sequence:
MESALFNFQSFLSLILLFICTCTYVKMIFPALLDRKIGFRGFFWKAARIECETDSIRKTG
The following text describes a protein:
Function:
Involved in the regulation of actin polarization. Rho proteins are required for distinct steps during polarized hyphal growth of A.gossypii.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MPLCGSSSSSKHPIERKIVILGDGACGKTSLLNVFTRGYFPKVYEPTVFENYIHDIFVDNQHITLSLWDTAGQEEFDRLRSLSYSDTHTIMLCFSVDSRDSLENVKNKWVSEIADHCEGVKLVLVALKCDLRSSDEYGNESAITPGSIQNQKYNGGGGNGLIPYDEGLAMAKQIGALRYLECSAKMNRGVNEAFTEAARCALTATPKGARDSAPEAESSSCTIM
The following text describes a protein:
Function:
Involved in the proliferation of osteoblasts during bone formation and bone regeneration. Promotes matrix assembly (By similarity).
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MLPPPRPAAALALPVLLLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPEECAAPRGCLAGRVRDACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLDTGGDLSRGEVPEPLCACRSQSPLCGSDGHTYSQICRLQEAARARPDANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRKDGLDIQLPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIPQLRSLNLVPEEEAESEENDDYY