The following text describes a protein:
Function:
Required during spermatogenesis for normal chromosome synapsis and meiotic recombination in germ cells. Necessary for formation of DMC1 and RAD51 foci on meiotic chromosomes, suggesting a specific role in DNA double-stranded break repair. Essential executor of PIWIL4-piRNA pathway directed transposon DNA methylation and silencing in the male embryonic germ cells. PIWIL4-piRNA binds to nascent transposon transcripts and interacts with TEX15, which may in turn recruit the epigenetic silencing machinery to the transposon loci. Not required for piRNA biosynthesis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTYFFIYVSTERACSLNNCTIAKRIGKGKDATVIFEHFRKPVDPFVQENCPCKALNSEMGPFSSDTSSSYGNVQNGNNSVLEAYNRQTENSSNLRDASQVYTHNSGFSFIPTGNTASGNGDLFSVTYLRSILSSISAAFPSHNNTGSSTVITSKLIKDPRLMKREQSMRNKSDTAGLSDVLPLDKSLGCGDSQIKLTCMPTSSISSSEVPADNTITSCLNASCFKFSSESSHYQAHNSSSKGHDCIASSSIAVTEQFKEQHSSSFPSSLSNAFSDVRKQKHSEEQVQRAQMRSNVPVLTALSSESRNSDESENTCSNDSQGHFSQESPSSDINSIYKVGHQMSTVFPAQKKGNLCEYIQDTGMMRASISTEDSTKDGVNHTWCKETVLSNETVSSPIDNSNTLYQEHKEGGNLNSLSGNCEKIGVTHKLQVPKFPISSTGDKNELYRAALELECSLTPTIECLSQKYPQHSLEHEDNTNFAMTQGLIELKTVQNNQNFGNILSDAFQEAKDVPLASEKLIDRVISSAAIDISLDSSVCNIIGEYTCVRRENENGEASPYNCHKEEASRVKDGVQDHSLSYDAELSCDLNLKINLQEQRDDKNPNEAKEHNTDNINGSEKQDCLANDHFTNIVEMREIKSNTEVEILNSEECFTFNSFRGKNGKPAETASSESEAVEQRHAPNDQRGLEHLVSSFPEIEGSSVCVASNATKQIVGTTVLTVSTSLGDHQKDELKEICSSESSDLGLVKHSISECEIDTDKDKLQDFHQLVNENSALKTGLGSEIEVDLEHDNASVFQQNMHSQGNDLCEEFELYESLKSRIDWEGLFGSSYEEIESSSFARREGTDQHSSTECNCVSFCSQDKRELHNPIFLPDLQVTITNLLSLRISPTDESLELKDNFYKQVTESTEPETNKEGNASGFGMCSQPSGENSSFSCANKFGNSVQESGDVSKSESSHSSNSSHNTHVDQGSGKPNNDSLSTEPSNVTVMNDKSKCPTKSKPVFNDTRNKKDMQSRSSKRTLHASSSRGQNIANKDLREHETHEKKRRPTSHGSSDRFSSLSQGRIKTFSQSEKHIRNVLNILNNEASLCKSKHLSRKLNKAVLHLKKAHRRVHTSLQLISKVGQKRKGPLPKAYAVIHNNFWESCDHQGDSLMSERRYSKHFLSKRKYDKQGDKRFLRFDIEESLTPVSKHRLYRTNRERIAECLSNEVMSGHVSSSLTTFHVREFCDEEQFPEPQLPLAYTSQSISQLEYTNSIVGNESSSELEHFSETSGNMLDPKETLTEKEYQTHTQLCNSDSAKLKNHTTHSIRDIAKECNSEDKTVLCESNPVYLSFIKENTSHSPDKSYDSNCKANTDIHISVLGSKKKHILSVDIYEQDNCVSDGVKSGEAIFPIEKCTVPMETTSSIPTENIASKSYTIPPVSSILVTAGEEESSVGENGLFDVNENEMNITMHSKLDLTSVTEESKICKKNMKNLSCNDSSMLLKENITGPSKRYMAKYIEEEKIRKIEQAVYKKIITEGSPISFKYKSQNKILKEKSFHVNKKIITNNLTDSHLSIKNSTVDTIALKDIPNQLKERKEAGQIKVNNNSHSDCLSKPAIVETNHRPVLHGNPKVATLQKELKEHRSPNYTSHVTELSQILQRADEAASLQILEEETKLCQNILPLFVQAFERQQECSIDQILISRKLLVEQNLWNNCRLKLKPCAVDTWVELQMAMETIQFIENKKRFLEGKPTFRSLLWYDESLYSELLRRPRGYQLQSNFYPGFQGRLKYNAFCELQNYHNQLVEFLTETKKENNSYYALLKYKRQINECEAIMKHYSDCFDFCLSVPFACGVNFGDSLGDLETLRKSTLKLISVPGGSPKVHSYPGKKDHLWIIIEIVSSKVSFIKSNEEISIKICLYGLEHIYFDAAKSLVWKEKSCSLPKKHSEKNREMEEINERAFSKLKKIYDVLSKGLNNEPTSIGLQEDAIIASKQSTLGSISNCRLNKAWLSYPDISCVGEILDQAKSADLEELQGLTLRCTDHLEILKKYFQMLQEDNIDNIFIMEENVLDMLSNHNLGAVILKPEAIEIYIEIVMISETIHYLKNLIAKKLHNQRFRGMLWFDWSLLPELIGCQEEVVSLSVGDTQTHCLWKLVETAISVLKKELAVIYEYGEASNCSYALHLFYRELKELTGVKRLLNNSKYSVSTYIDLVPHTASVNFGNTVAELEHNYKQFFLLLKNVMSVPQKDFGKMVHIIKVMKTIEHMKLLSAKDTKLSTHLLFLQMLRNKRNALQQNRQEKMETPVTEPGEDSSQPGVSEQTPPGTECTVKNISDSSKKRPVTADTCEVSQGKGNTDTVPSWKKQKVTMKDVGNIQTVSKHPSTTGSPPNDENKIGSNSSDSLKSISASPEVVKRQSSVLGSVSPAESVQDTCTPKSESKVEPTDSLPDSLASLTEQQENSNVIEKRNGNSSVAETNDKKDCPLVTCDQKDIDASYSPDHTPAQESHKTPVDHTQISPSNLTAGNDDPLVPDASLLSVSASQSEKDVYLSGTDFHHENNKILNLSTEDCTGTSSPEPVCIKDKISVLQVDKTQPIKSESPKKSMTDAPNPNTAPFGSYGNSALNVNGTVQHTHSEQNSKVLTQKVGTSRNIPPQSACSPVHNSSAHSFGTSYPYYSWCFYQYSSSNGTAVTHTYQGMTAYEIQQPPPPVLTTVASTVQSTHFNRSYSEHFSYFPGQPQANSFNPGNGYFPSHTPVSYNYQQPVYSQFASHQPVPQATYPYPPNPGAPPQVPWTYAPWQQNPFLRRP