lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
QVTFSDVAIDFSHEEDLYKDVMVQNYENLVSVAGLSVTKPYVITLLEDGKEPWMMEKKLFLFSYTVLSIMYILPISVITPASSVNSVFSAPFEHCSEIIEIFELSELCVFWGLQFLSISPNSTIEVSFQGVKKRKKQCFAFLIYFRFTPNSNNRKKFEHIEKLEGNPTGDIYKYDTFGITFHSKLNGGKKLLNSNKSGAAINQSTSPHQTCNRETFGKQSILNRHWRIHTGEKPCECRECGKTLSHGSSLTRHQISHSGEKPYKCIECGKAFSHVSSLTNHQSTHTGEKPYECMNCGKSFSRVSLLIQHLRIHTQEKHYECRICGKAFIHRSSLIHHQKSHTGEKAYECRECGKAFCCSSYLTPHQRIHTMEKQYECNKCLKVFSSLSFLVQHQSIHTEEKLFECQKCRKSFNQLESLNMPLRNHIRLKCDFYLMNAIYVGKLSVIGHPCFNITEFILERNLMNVLNVGRPSAVVQTLLYIREFILEKSHINVMSVGKLLAKAQILLPIKEYIMERNPIVW
The following text describes a protein:
Function:
Serine protease inhibitor that plays an essential role in male reproduction and fertility. Modulates the hydrolysis of SEMG1 by KLK3/PSA (a serine protease), provides antimicrobial protection for spermatozoa in the ejaculate coagulum, and binds SEMG1 thereby inhibiting sperm motility.
Subcellular Localization:
Secreted.
Sequence:
MGSSGLLSLLVLFILLANVQGPGLTDWLFPRRCPTIREECEFRERDVCTRHRQCPDNKKCCVFSCGKKCLDLKQDVCEMPNETGPCLAFFIRWWYDKKNNTCSTFVYGGCQGNNNNFQSEANCLNTCKNKRFP
The following text describes a protein:
Function:
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MIILEAHSAIVKTLLERSLDPNDKLSESYECCDFDGVSFLIRLEKPKGAKDENAKYPVRVEMKLPCWEAIKQYGAEERYKELYGKWKVAPTDGRTHAVVVNLWEMSAAEQKATIELIANLKPNMLGAPFLWVAKKVNAKENFAPFEIPYRAHTGESIFLSPAEKGATAIFTIRFNDPGDRIIGNVFFGELAAARTRVRSAPIVAFSDKCPGELEAFHLRPEVKDGSLFAYVSMSLLAASLSERKRQDTSVYVPMFRDYLHYHIKCTKAFLHQKMRNRTALLLKILDEAKPEPKVKVARTVTGKIVNH
The following text describes a protein:
Function:
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MEKNETLKLGLKLFIITAIAGLILGGAFVITKKPIADQVEKTNTEAMKEILPKADKFEKMEGKAKDAVTEVNEGKKGNDVAGYAIKVLTKGYGGQIEMMVGVSKEGKVEGIKILSHSETPGLGANAPQPKFSGQFKGKSTEKDLEVVKTAPGKDNEIEAMTGATITSKAVTKGVNDAVKFYKDELLKTPSESKEVDGKSGATTSFNTEDTKLNKYVVNYEKMN
The following text describes a protein:
Function:
Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
Subcellular Localization:
Nucleus.
Sequence:
MALAPMGPEASFFDALDRHRASLLAMVKKGAGETPDRATRVPSSSEVLTSIENIIQDIIKSLARNEAPAFTIDNRSSWENMTFEDAFGLQMRPQCTTRKIKSDSLRSVRKFALILKILSMIYKLIQSNTYATKRDIYYTESQLFRNQAAVDSIIDDISCMLKVPRRSLHVISTSKGLIAGNLRYVEEDGTQVQCMCSATATAVPSNIQGMQNLVTDAKFLLIVEKDATFQRLLDDNFCSRMSPCIMVTGKGTPDLNTRLLVKKLWDTFHIPVFTLVDADPYGIEIMCIYKYGSMSMSFEAHNLTVPTIRWLGLLPSDIKRLNIPKDSLIPLTRRDQMKLDSILRRPYITYHPFWKKEMEMLADSKTKAEIQALSFLSSDYLSRVYLPNKLRFGGWI
The following text describes a protein:
Function:
Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.
Sequence:
MAFRKAVKGTILVGGGALATVLGLSQFAYYRRKQMSLVDAEAADCISEPVNREPPSRDAQLLTLGSGCVLDTKNSLVERDDYLPGTSSRSTNLIHGGVRHLQKAMMKLDIEQYWMVTEALDERVNLPEISPHLSAPLPIMLPVYKWWQLPYYWVGIKLYDLVAGSNCLKSSYVLSKSGALEHFPMLQKDKLVGGIVYHDGRHNDAWMNLAIVLTAARYGDATVNDREVVTKVRVSGAWCKDVLTGQEFDMKAKCVINAVGHFTDSVCKIDDKDAAAIRQPSAGVHIVMPGYYSPEIISFLPWQKMMIAGTTDTPTDITHHPKAINFILNEARNYLSCDKRGDILAVWSGICPLVTDPKSADTHERGLITTAGGKWTTYRRTAGLFLQGGKDWNPTLYMKLFQDYGLESEGAQHLAATYGDKAFEVATVASVTSKRWPIVGVCLVSEFPYIEAEVNYGIKEYSCTTVDMISRCTRLPCLAFLNVRAAEEALLRTVELMDDYKKQEQLETTRNLLPSDSDRYKKRFRKSDADQKGFITIADVPCVLESINVQMDENTLHEILNEVDLNKNGQVELNEFLQLMSAIQKGRVSGSRLAILMKTAEENLDRRVPIPVDHSYRRDRA
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MGLDDGTSRKDDIESDRIEEPLLDKKDYTLRGYQNQPDSVVSIPSSQEGSSVFGYNVGVRPFQDVSFAIIFLLLVVISVAFGIYGVVHSNSEYQWVETAQYEPKQQTCSIPEGMLLEPMQASDAKWQIAYVIMPQRLKNLLFSSRAPSATPIWITLGIALVLSGPFALGVLFLLRVYTKELVYATLPLIILLPIVLNLTWFILCQRSEECLKEFDPAGQYVLFGIILLMCALMIYVIYSNWDRIQLTIRIVKTSSEALHQNLALLFVLPGLSLVLVVFCVPFVIFIGYSYTNGKVVPNPDVLAGESIQCARGTDTPCCVWQTASWVPYYMYLSGFSVLWSSTIMAQIQVFTISGTISQWYFAQAGSSAMNSTRRALSVAFGPSFGTACLAGLVVAIVRIIRGAANSTDNEQAQESALAIFLRACLQSILDAVEFFTRFTTNFAAITGESFCNSASMTYNLLKRNLLSTVLVEIISDRLLAMVTFVLTLVYALLIYGVLSLSTSLAKDQKLIAAVLSWLIVFLVLVLFVRVLSNIIDTVYICYAMDKDQGVVSKSEVHDVLVLLPASQEENPSLAVRREN
The following text describes a protein:
Function:
Involved in the anaerobic metabolism of phenylalanine and phenylacetate. Catalyzes the oxidative decarboxylation of phenylglyoxylate to benzoyl-CoA and CO(2). It can also react slowly with 2-oxo-3-methylbutanoate and use different electron acceptors such as benzyl viologen, methyl viologen, FAD or FMN, but NAD seems to be the physiological electron acceptor. Also catalyzes an isotope exchange between CO(2) and the carboxyl group which proves partial or complete reversibility of the oxidative decarboxylation reaction.
Sequence:
MDRAIEHTKYLIAGSSHAALEAINAIRMHDAEGPITVVTRDAHLPYSPTVLPYVVSGKSAPERIFLRDDDFFARNKVAYRPKAALKALHADRNTAELADGSSVVYEKLLLATGASPAIPPIPGIDTVSYHVLRTLDDALKLRGAIAESKQAVVLGAGLVGMHAAENLVKAGATVTIVEMSEQLTSGYFDKVAADMIEQAFRDAGGKIMTGSRVVRLEPTAAGAKLTLENGTTLEADLLLVATGVKPEMDYLNGSGVEHAQGILVDDRMQTTAENVWAAATAQARGFFTGTKVMNAILPDATIQGRVAGMAMAGDPGVKDYAGAVPLNTYHFFGRHAISVGSSTVPEGGEVVTRFDEKTGRYLKAIFAADGPLTGIFGVNEFFDGGVMAQLILRRTDLTPLRSRFVANPLAVGREIMSQTWR
The following text describes a protein:
Function:
Snake venom zinc metalloproteinase that calcium-independently catalyzes the conversion of prothrombin (F2) to alpha-thrombin through the formation of a thrombin intermediate.
Miscellaneous:
MISCELLANEOUS: Negative results: does not have an affect on factor X (F10) and fibrinogen.
Subcellular Localization:
Secreted.
Sequence:
TNTPEQDRYLQVKKYLEYVVVDNNMYRNYGNAGPCVMSAEISFEPLQEFSSCDIQEPLSQDIVQPAVCGNYYVEVGGECDCGSPKPCRSACCNAATCKLQREHQCDSGECCEKKDDCDLPEICTGRSAKCSCVISQGDLGYGMVEPGTKCTDGMVCSNEQCVDVQTAAK
The following text describes a protein:
Function:
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
Sequence:
MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK
The following text describes a protein:
Function:
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MVNKINELNNYFRINSTFINKSENESENFYVWTYKSPNVDLYPDLVFFKCQVLNINGDNYEVKEISPETNSVYTVKKEHLFNCNNMVNINSHRLNDMVHQNSAEVLNTLALRYEKNYIYTIAEPMLISVNPYQVIDTDMNEYKNKSTDLLPPHVYTYAKDAMLDFINTKNSQSIIISGESGSGKTEASKLVIKFYLSGVREDNDISKTLWDSNFILEAFGNAKTVKNNNSSRYGKYIKIQLDENQNIVSSSIEIFLLEKIRVVSQEPDERCYHIFYEILKGMNDEMKKKYKIKSEEDYKYISNKSINIPEIDDAKDFENLMISFDKMKMSDLKDDLFLTLSGLLLLGNIQFNGIEKGGKSNCSELDDENLEVVNEASELLGIDYESLKNSLVITEKSIANQKIEIPLSIEESLSICRSISKDIYNKIFEYITKRINNFLNNNKELENFIGILDIFGFEIFVKNSLEQLLINIANEEIHNIYLFVVYEKESNLYKKEGIIIESVKYTNNESIIDLLRGKTSIISILEDNCLAPGKKDESIVSVYTNKFSKNEHYSVCKKNITESFVIKHTVSDVTYSISNFISKNKDILSPNILKLLKVSNNKLIQNLYDDAEVTDSLGRKNLITYKYLENLKKICSYLKSTNIYFIKCIKPNETKEKNNFNPKKVYPQLFSLSIVETLNIKYFFQYKYTFASFLSYYQYLDIAVSNDSSLDEKTKVTMLLERNFDKDSYKVGHTMVFLKKEAVHKIRDIINSNLKCYRNLCCITSALIMKIKKKRIVEENIKNLQLAQAYFRKYKYIKEHE
The following text describes a protein:
Function:
Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. May function in skin immunity. Enhances myeloid progenitor cell survival in vitro. Induces RETNLA and serum amyloid A protein expression in macrophages.
Miscellaneous:
MISCELLANEOUS: Il31 transgenic mice develop dermatitis. A similar phenotype is caused by local delivery of Il31.
Subcellular Localization:
Secreted.
Sequence:
MIFHTGTTKPTLVLLCCIGTWLATCSLSFGAPISKEDLRTTIDLLKQESQDLYNNYSIKQASGMSADESIQLPCFSLDREALTNISVIIAHLEKVKVLSENTVDTSWVIRWLTNISCFNPLNLNISVPGNTDESYDCKVFVLTVLKQFSNCMAELQAKDNTTC
The following text describes a protein:
Function:
May act as a guanine nucleotide exchange factor (GEF).
Sequence:
MAKHGADEPSSRSGSPDREGRASEDRSLLHQRLAVRELIDTEVSYLHMLQLCASDIRSRLQQLPQGDLDVLFSNIDDIIKVNSRFLHDLQETASKEEEQVQLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQGIVEAVVPQAGSSGLSFLLVIPLQRITRYPLLLQKILENTVPDASAYPVLQRAVSALQDVNTNINEYKMRKEVASKYTKVEQLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRTEDKEFDDLEERFQWVSLCVTELKNNVAAYLDNLQAFLYFRPHEYNLDIPEGPAVQYCNLARDLHLEAFLKFKQRLEGLVWQPLCSLAKALLGPQNLIKKRLDKLLDFERVEEKLLEVGSVTYQEEAARHTYQALNSLLVAELPQFNQLVMQWLGQIMCTFVTLQRDLAKQVLQRAEGSMAQLPHHHVPEPAFRKLVEDALGRTSNQLRSFQETFEKVQPPPTTQPLLPGSERQVQALLSRYGPGKLYQVTSNISGTGTLDLTLPRGQIVAILQNKDTKGNSGRWLVDTGGHRGYVPAGKLQLYHVVPSAEELRRQAGLNKDPRCLTPEPSPALVPSIPTMNQVIAAYPFVARSSHEVSLQAGQPVTILEAQDKKGNPEWSLVEVNGQRGYVPSGFLARARSPVLWGWSLPS
The following text describes a protein:
Function:
Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box via its C-terminal ATPase activity. Both transcription activation and repression require its ATPase activity.
Miscellaneous:
MISCELLANEOUS: Present with 6560 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion. Nucleus. Note=Localized on chromatin. Specifically localized to the promoters of the genes it regulates.
Sequence:
MTSRVSRLDRQVILIETGSTQVVRNMAADQMGDLAKQHPEDILSLLSRVYPFLLVKKWETRVTAARAVGGIVAHAPSWDPNESDLVGGTNEGSPLDNAQVKLEHEMKIKLEEATQNNQLNLLQEDHHLSSLSDWKLNEILKSGKVLLASSMNDYNVLGKADDNIRKQAKTDDIKQETSMLNASDKANENKSNANKKSARMLAMARRKKKMSAKNTPKHPVDITESSVSKTLLNGKNMTNSAASLATSPTSNQLNPKLEITEQADESKLMIESTVRPLLEQHEIVAGLVWQFQGIYELLLDNLMSENWEIRHGAALGLRELVKKHAYGVSRVKGNTREENNLRNSRSLEDLASRLLTVFALDRFGDYVYDTVVAPVRESVAQTLAALLIHLDSTLSIKIFNCLEQLVLQDPLQTGLPNKIWEATHGGLLGIRYFVSIKTNFLFAHGLLENVVRIVLYGLNQSDDDVQSVAASILTPITSEFVKLNNSTIEILVTTIWSLLARLDDDISSSVGSIMDLLAKLCDHQEVLDILKNKALEHPSEWSFKSLVPKLYPFLRHSISSVRRAVLNLLIAFLSIKDDSTKNWLNGKVFRLVFQNILLEQNPELLQLSFDVYVALLEHYKVKHTEKTLDHVFSKHLQPILHLLNTPVGEKGKNYAMESQYILKPSQHYQLHPEKKRSISETTTDSDIPIPKNNEHINIDAPMIAGDITLLGLDVILNTRIMGAKAFALTLSMFQDSTLQSFFTNVLVRCLELPFSTPRMLAGIIVSQFCSSWLQKHPEGEKLPSFVSEIFSPVMNKQLLNRDEFPVFRELVPSLKALRTQCQSLLATFVDVGMLPQYKLPNVAIVVQGETEAGPHAFGVETAEKVYGEYYDKMFKSMNNSYKLLAKKPLEDSKHRVLMAINSAKESAKLRTGSILANYASSILLFDGLPLKLNPIIRSLMDSVKEERNEKLQTMAGESVVHLIQQLLENNKVNVSGKIVKNLCGFLCVDTSEVPDFSVNAEYKEKILTLIKESNSIAAQDDINLAKMSEEAQLKRKGGLITLKILFEVLGPSILQKLPQLRSILFDSLSDHENEEASKVDNEQGQKIVDSFGVLRALFPFMSDSLRSSEVFTRFPVLLTFLRSNLSVFRYSAARTFADLAKISSVEVMAYTIREILPLMNSAGSLSDRQGSTELIYHLSLSMETDVLPYVIFLIVPLLGRMSDSNEDVRNLATTTFASIIKLVPLEAGIADPKGLPEELVASRERERDFIQQMMDPSKAKPFKLPIAIKATLRKYQQDGVNWLAFLNKYHLHGILCDDMGLGKTLQTICIIASDQYLRKEDYEKTRSVESRALPSLIICPPSLTGHWENEFDQYAPFLKVVVYAGGPTVRLTLRPQLSDADIIVTSYDVARNDLAVLNKTEYNYCVLDEGHIIKNSQSKLAKAVKEITANHRLILTGTPIQNNVLELWSLFDFLMPGFLGTEKMFQERFAKPIAASRNSKTSSKEQEAGVLALEALHKQVLPFMLRRLKEDVLSDLPPKIIQDYYCELGDLQKQLYMDFTKKQKNVVEKDIENSEIADGKQHIFQALQYMRKLCNHPALVLSPNHPQLAQVQDYLKQTGLDLHDIINAPKLSALRTLLFECGIGEEDIDKKASQDQNFPIQNVISQHRALIFCQLKDMLDMVENDLFKKYMPSVTYMRLDGSIDPRDRQKVVRKFNEDPSIDCLLLTTKVGGLGLNLTGADTVIFVEHDWNPMNDLQAMDRAHRIGQKKVVNVYRIITKGTLEEKIMGLQKFKMNIASTVVNQQNSGLASMDTHQLLDLFDPDNVTSQDNEEKNNGDSQAAKGMEDIANETGLTGKAKEALGELKELWDPSQYEEEYNLDTFIKTLR
The following text describes a protein:
Function:
May be involved as a regulatory molecule in GPR24/MCH-R1 signaling.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm.
Sequence:
MTDFKLGIVRLGRVAGKTKYTLIDEQDIPLVESFSFEARMEVDADGNGAKIFAYAFDKNRGRGSGRLLHELLWERHRGGIAPGFQVVHLNSVTVDNRLDNLRLVPWGWKPKAEDLSSKQREQSLYWLAIQQLPTDPIEEQFPVLNVTRYYNANGDVVEEEENSCTYYECHYPPCTMIEKQLREFNICGRCQVARYCGSQCQQKDWPAHKKHCREKKRTFQQELGPER
The following text describes a protein:
Function:
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MPAPAAKASNRPRLLQQRPDKHAQQGGGRKGFFSGPFFYLFVLGAPIVLACLSLKFLADVPMRGSDVEVLLPPIPAPVNDSGLTWGTLRAQHYFGLRTRHPHSPLFGMMWFDQPQGGHPNIRHWCHDKEVNSYGWTQADGRSFGRQTINDTTVLLQTDWVNTKESTFTARVTSKPHKAKKQNGAAAPRVNFYFYLALESPAHGRLWLQESKEIAIEGRTEELGEFVLKIESAKREEAIVTDLLLPRVNLARLNDHVLEKMRVSQTQHGIAYVLAQGEQKVTEGTFAVMAINAPAETSFEITFSRAAAHQPPPTGAAFDGILTKRVEQFEQRFERAFALAEKNYSPSESAMARVALSNMLGSIGVWHGSNKVKQFGGIVPYGPHTLLSAVPSRPFFPRGFLWDEGFHQLLISRFDPVLSLECVTSWLNTMNVNGWIPREMILSAEAEAKVPAEYVAQDPSVANPPSLFYLLDTVTRDSMFVNQHRATFSAIYFKAAKWYQWLITSQAGRYSDSLRWRGRNGTTKAELNPKTLASGLDDFPRASHPSDKEYHLDLRCWMAVASRVLARLAETFSTADEAESYRRKYTELSDFGNLVQRHWTEEGKQFADFGLHSLNVRLVQREKLVQGHHGNTKETWMERAVDEPPKERHVSDAMGYVGLFPLIAHIVPATEHAKLRAILGHLNDPEELWTPFGIRSLSTLSPYYQARNTEHDPPYWRGSIWMPINYLLLRSLGEYAAEPGLDAALREEFVGTHRRLKKALVGNLAKGKGTHPMTGWTSLVLMVMSEDDL
The following text describes a protein:
Function:
Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Acts early in neural plate development to induce expression of some but not all proneural genes, and specify a neural precursor state. Also up-regulates repressors that prevent neuronal differentiation. Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes. Acts primarily as a transcriptional repressor during neural development, and binds to the bmp4 promoter to repress gene expression and thus mediate down-regulation of bmp4 by wnt signaling. Controls multiple processes through bmp4-repression including neural plate development, neural crest specification and Spemann organizer development. Involved in the specification of the preplacodal field at the anterior border of the neural plate. Regulates the genetic cascade of interactions that are necessary for positioning the isthmus organizer and the formation of the midbrain-hindbrain boundary. Required during at least two stages of pronephros kidney development; during neurula stages, maintains transcription of key renal genes to define the size and identity of the pronephric anlage, probably in part through regulation of bmp-signaling. Subsequently required for proper formation of the intermediate tubule segment of the pronephros. Acts principally as a transcriptional activator during pronephros development (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSFPQLGYPQYLTAGQGAVYGGERPGVLAAAAAAAAAAGRPTGAELGSCPTAAVTSVLGMYASPYSSPNYSAFLPYTTDLTLFSQMGSQYELKDNPGVHPATFAAHTTPGYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGAMGKEDDNIFGSDNEGDHEKNEDDEEIDLESIDIDKIDDNDGEQSNEEEDEKLDHFRHGEKVSLKKESEVMIPSSDGLKPKDSLSLGKECSDTSNTRIVSPGGQGNIQAPPHSKPKIWSLAETATSPDGALKSSPPPSQANHTSPQMQHPAFLPSHGLYTCQIGKFHNWTNGAFLTQSSLINMRSLLGVNPHHAAHHNHHHLQAHQQSTLLATNLGSLSSDRTPERTSPKHSDRENLPRTESPPQLKPSFQAVREKTFSQQEGTSRILTALPSA
The following text describes a protein:
Function:
May function in depolymerizing pectin during pollen development, germination, and tube growth. Acts as an exo-polygalacturonase.
Subcellular Localization:
Secreted. Secreted, cell wall. Golgi apparatus. Endoplasmic reticulum. Vesicle. Note=After 5 minutes in germination medium, detected as a soluble protein and released from apertural and non-apertural regions of pollen grain wall. After 15 and 30 minutes, abundant in the germinal aperture. After 2 hours in germination medium, localization in these regions decreases. In mature, non-hydrated pollen grains, abundant in cisternae and vesicles of Golgi in the apertural region. Sparse in the center of the cytoplasm, associated with cisternae and vesicles of the endoplasmic reticulum (ER) and abundant in the generative cell wall. After 5 minutes of hydration, localization to these regions decreases. After 15 minutes of hydration, present around emergent pollen tube and in the center of the vegetative cell, both in the ER and Golgi. After 30 minutes of hydration, present in juncture between pollen wall and pollen tube. Abundant in the ER cisternae, which show a disorganized and interrupted concentric structure with numerous ER vesicles linked to Golgi vesicles.
Sequence:
RGVQSSGSVFNVNDYGAKGAGDISQAVMKAWKAACASQGPSTVLIPKGNYNMGEVAMQGPCKGSKIGFQIDGVVKAPADPSKFKSDGWVSFYRIDGLTVSGTGTLDGQGQTAWAKNNCDKNPNCKHAAMNLRFDFLKHAMVRDITSLNSKMFHINVLECEDITFQHVTVTAPGTSINTDGIHVGISKGVTITNTKIATGDDCISIGPGSQNVTITQVNCGPGHGISIGSLGRYNNEKEVRGITVKGCTFSGTMNGVRVKTWPNSPPGAATDLTFQDLTMNNVQNPVILDQEYCPYGQCSRQAPSRIKLSNINFNNIRGTSTGKVAVVIACSHGMPCSNMKIGEINLSYRGAGGPATSTCSNVKPTFSGKQVPAIKCA
The following text describes a protein:
Function:
Plays an important role in the cytoplasmic envelopment of tegument proteins and capsids during the assembly and egress processes. Also participates in viral entry at the fusion step probably by regulating the core fusion machinery.
Subcellular Localization:
Virion tegument. Virion membrane; Lipid-anchor. Host cell membrane; Lipid-anchor; Cytoplasmic side. Host Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Note=Virion membrane-associated tegument protein. Associates with host membrane lipids rafts. During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Sequence:
MGALWSLCRRRVNSIGDVDGGIINLYNDYEEFNLETTKLIAAEEGRACGETNEGLEYDEDSENDELLFLPNKKPN
The following text describes a protein:
Function:
Integrase from the cryptic lambdoid prophage e14. Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
Sequence:
MAARPRKNNVSVPNLYPLYSRKVNKVYWRYKHPVTGKFHALGTNEAEAIAIATEANTRLAEQRTRQILAISDRIATSKGKAITTSTWLDRYQAIQDDRLKSGDIRLNTYKQKAKPVSLLRERAGMKLISAVDVRDIAQLLDEYIAAGRPRMAQVVRSVLIDVFKEAQHYGEVPPGYNPALATKQPRRKITRQRLSLEEWKKIFDIADATHRYMGNAMLLALVTGQRLGDISRMKFSDIWDDHLHVIQEKTGSKIAIPLSLRLNAINWSLRDVVARCRDYAVSAYLVHFFRSTSQAERGAQVKANTLTMNFSKARDLARIDWGEGSPATFHEQRSLSERLYKEQGLDTQKLLGHKTQQQTDRYHDDRGKGWSKVAL
The following text describes a protein:
Function:
Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching (By similarity).
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MEWISHLENDDDVLEIEDYKVRKDALLIAIQVTQNAINNGTLHKALEAAFDAVTDRIVISPQDYTGVMLFGASMQSEDDGDEFDDESDTHFILKLGLPTAAQIKRLKRLAEDPDLGERFKVQEEPHLMDVFFDMNRHFINMAPNFASRRIIYITDDDTPTTNEDDINKTRVRIEDLSHLKVKVEPLLINPSEDKTFDSSKFYALVFNEDTSVEPVEAIDLKQFINKRNVLNRSLFNVKMEIGEGLVVGVRGYLLYAEQKATSTTRKAWVYTGGEKPEIAKLESQAVTIESGRSVDKADLRKTFKFGNDYVPFTEEQLTQIRYFGEPIIRILGFHNSSDFSELFIHSVRSSMFLYPTDEKLVGSIRAFSALYQSLKNKDKMALAWVIVRKGAKPILALLIPSTKEIEGLHMVFLPFTDDIRQEPKTELVSAAPELVDATKNIFTRLRMPGGFESQRYPNPRLQWHYRVVRAMALQEEVPKVPEDKTTPKYRSIDTRVGDAIEEWNKVLQSSSKRPAEDICKAEKKVKSSDAGPPSNEQMQNMVENDIVGKLTVAELRAWGAANNVEPNGSKLKKDWVEVVKKYYGK
The following text describes a protein:
Function:
Essential protein required for nuclear division and organization during embryo sac development in female gametophyte, probably by promoting rRNA biogenesis essential for the progression of the mitotic division cycles during gametogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus. Note=Localized in the nucleolus in interphase cells.
Sequence:
MEEELRVRLNDHQVSKVFPVKPKSTAKPVSESETPESRYWSSFKNHSTPNLVSSVAALAFSPVHPHSLAVAHSATVSLFSSQSLSSSRRFSFRDVVSSVCFRSDGALFAACDLSGVVQVFDIKERMALRTLRSHSAPARFVKYPVQDKLHLVSGGDDGVVKYWDVAGATVISDLLGHKDYVRCGDCSPVNDSMLVTGSYDHTVKVWDARVHTSNWIAEINHGLPVEDVVYLPSGGLIATAGGNSVKVWDLIGGGKMVCSMESHNKTVTSLRVARMESAESRLVSVALDGYMKVFDYGRAKVTYSMRFPAPLMSLGLSPDGSTRVIGGSNGMVFAGKKKVRDVVGGQKKSLNLWSLISDVDESRRRALRPTYFRYFQRGQSEKPSKDDYLVKEKKGLKLTRHDKLLKKFRHKEALVSVLEEKKPANVVAVMEELVARRKLMKCVSNMEEGELGMLLGFLQRYCTVQRYSGLLMGLTKKVLETRAEDIKGKNEFKGLLRNLKREVNQEIRIQQSLLEIQGVIAPLMRIAGRS
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Required for the pollen tube micropylar guidance and embryo development by regulating GPI-anchor mediated protein localization (e.g. COBL10 and A36).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVVYVVNHAFP
The following text describes a protein:
Function:
Appears to be a structural component of the chitin synthase 3 complex.
Sequence:
MRLPEISIWKVILLLHLFALQEFQLVSAANLPSLSSSTKAADSSSKGSSSAKTTTSLGKSSVTSKDVSSSHNVTSSTKMPKITTSASTSLYTNSSLWSNNSVISTSSITPSSVYIPVTDGNKFLYQAHHPNGTVFIAFAGCLGAILLSLTGAWIALNIKSWRSARKENKLRNLENQYQHDPFYFQTNINDDESETSSHSDDSDISEKVLKNNSSRMSLYTLGSTSVLNLLNNKTDANDNFRSSMFISPTEILQSDANNSNTWSQSNESAIYDSLSSTPREPGATQILGKFTDSTNPFNYTSYNLSPDSEDRSTPKSNVSQGKVKKYRPPSVHLDQLLDGKE