lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
ATP-binding RNA helicase involved in mitochondrial RNA metabolism. Required for maintenance of mitochondrial DNA (By similarity).
Subcellular Localization:
Mitochondrion.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MLIGQVSRLSAIPPLALQHTLRPLHSSSVLAAGGKRPKQSPSHSRNSPRQKPDWEKRGSNRGRSEQPRASRFGLKSSGTTSFRSEPPRARRVISDSSSGSSASITPKGQHVPTSSRRLLPFSSSDTIPKPSHRFKLEPATMPPNLTPRSFNRDDGVTEEYINGLPAYPTPPTTLANEEQARPRTFDDFGLEEGLVKSLKGLYGEDGKTTPIETLSFHHFTQPDIASAPIGSQRVLLGAETGSGKTVSYLIPLFHHLKRTDPGPSVTSSFFADSENTLHPRSIILSPTHELTRQSTQFAKILTHNTKLSVHGMSSTVSGGVGEKRGSVDVLLGTVGSLRRMFGMTRSEEEQEKEDYIRGKRIWQDEQEKGMVEGDKVEWVVIDEADVLLGREFYLDTISVLSQVKQANLILCTATLPPFLINLLTTNPFFTKKEPFIHLLSPGLHKLPPKLLTRFIRPSTTGNKHGDVAHQVRLTLAEDAKAAKAEGREGEEPSKIVIFCNSDKQVEQVSGILGTKKIDCLAWTGAGEERLRGRNGSLNDFLQRPHLPGHEPPAPLPSLEPRETKPIFQDKNGTTPNVSQVTRRRVLVTTSLLSRGLDFHPSVSSVFLVQPPRDVLDFVHRAGRAGRAGRPGRVVVFGIDEGGTLGEGAKNNKGGKGQGPLKKDGKTALGDRLKDVLGKREVVGAMGKRVRT
The following text describes a protein:
Function:
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
Subcellular Localization:
Cytoplasm, cytosol. Mitochondrion.
Sequence:
MFDLFGFIRQLIGSMLAIFSFGKKKLSNSLSVYVKTNTGNTLAVDLEPHMDIKDVKEMVAPRLGLEPQELKIIFAGRELSDTTTISECDLGQQSIIHVVKSRPTAITTPQKRQAKPALNATISEEPSPEEQQQHNKPLSETMSELTVLDERNGDQSIPIGRTKAHFFVYCSQCEKVCTGKLRVRCGICGSGAFTVHRDPTCWDDVLKRKRITGHCENYEVPCVENDEGEPPFTEFYFKCSEHSSGGEKDFAAPLSLIKTNHKNIPCIACTDTSETILVFPCVAGHVSCLDCFRQYCVTRLLERQFVEHPTGGYTLQCPAGCDNSFIEDVHHFKLLNKEQYERYQRFATEEFVLKNGGVLCPQPGCGMGLLVDPECRRIQCQNGCGYVFCRSCLQGYHIGECFETPTPSTPGNEQGYAIDPLRASEARWDEATKIAIKVTTKPCPQCRTATERDGGCMHMVCTRSGCGFEWCWVCQTPWTRDCMAAHWFG
The following text describes a protein:
Function:
Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
Subcellular Localization:
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Domain:
The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
Sequence:
MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLSLAELKDKLDEMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRLTLEAIRVTQSDRDLFKHLISEATDYVAADYMRHANERRVHLDQALAFRRDLYTSRKQLAAEQYKHVDMARELGEHNGAEGSLEADYQAASDHLNLVQTALRQQEKIERYEADLEELQIRLEEQNEVVAEAAEMQDENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAISALARAKELCHLPDLTPESAAEWLDTFQAKEQEATEKLLSLEQKMSVAQTAHSQFEQAYQLVAAINGPLARSEAWDVARELLRDGVNQRHLAEQVQPLRMRLSELEQRLREQQEAERLLAEFCKRQGKNFDIDELEALHQELEARIASLSESVSSASEQRMALRQEQEQLQSRIQHLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQEVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGAEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQIAEQLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPSLPIFGRAARENRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLSVAFEDDPEAEIRRLNGRRVELERALATHESDNQQQRLQFEQAKEGVSALNRLLPRLNLLADETLADRVDEIQERLDEAQEAARFVQQYGNQLAKLEPVVSVLQSDPEQFEQLKEDYAWSQQMQRDARQQAFALAEVVERRAHFSYSDSAEMLSGNSDLNEKLRQRLEQAEAERTRAREALRSHAAQLSQYSQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARQRRDELHAQLSNNRSRRNQLEKALTFCEAEMENLTRKLRKLERDYHEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQSVSFGQVNSVRLNVNVRETHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDEARRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTQTEDTPSEAS
The following text describes a protein:
Function:
Aminopeptidase with broad substrate specificity to several peptides.
Sequence:
MWLAAAAPSLARRLLFLGPPPPPLLLLVFSRSSRRRLHSLGLAAMPEKRPFERLPADVSPINCSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFEATDARRAFPCWDERAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVTSTYLVAFVVGEYDFVETRSKDGVCVCVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWDLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLRLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAAAGNL
The following text describes a protein:
Function:
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
Sequence:
MINKTLLQKRFNGAAVSYDRYANVQKKMAHSLLSILKERYSETASIRILELGCGTGYVTEQLSKLFPKSHITAVDFAESMIAIAQTRQNVKNVTFHCEDIERLRLEESYDVIISNATFQWLNNLQQVLRNLFQHLSIDGILLFSTFGHETFQELHASFQRAKEERNIKNETSIGQRFYSKDQLLHICKIETGDVHVSETCYIESFTEVKEFLHSIRKVGATNSNEGSYCQSPSLFRAMLRIYERDFTGNEGIMATYHALFIHITKEGKR
The following text describes a protein:
Function:
Specifically methylates the N7 position of a guanine in 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MKELKDFFKKCFSSILINSLKLPDDDKQIEVLADKFLFYLSELKKWNKAYNLTSIEDEKEIIVKHFIDSLLYLCFISENPLSIADIGTGAGFPGIPIAIVRPRAKITLIEPSWKKNAFLKNIKRKLELENIEIIKAKAEEIHNKFDIVISRALWSIKDFIKHCNHLLKKEGYFLISKSLKIDEEIQNLPERYNIEIREFELPDINSSQIGGKRYIIKIEKCES
The following text describes a protein:
Function:
[Cyclic AMP-dependent transcription factor ATF-6 beta]: Precursor of the transcription factor form (Processed cyclic AMP-dependent transcription factor ATF-6 beta), which is embedded in the endoplasmic reticulum membrane. Endoplasmic reticulum stress promotes processing of this form, releasing the transcription factor form that translocates into the nucleus, where it activates transcription of genes involved in the unfolded protein response (UPR); [Processed cyclic AMP-dependent transcription factor ATF-6 beta]: Transcription factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein; [Processed cyclic AMP-dependent transcription factor ATF-6 beta]: Nucleus. Note=Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
Domain:
The basic domain functions as a nuclear localization signal; The basic leucine-zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE.
Sequence:
MAELMLLSEIADPTRFFTDNLLSPEDWGLQNSTLYSGLDEVAEEQTQLFRCPEQDVPFDGSSLDVGMDVSPSEPPWELLPIFPDLQVKSEPSSPCSSSSLSSESSRLSTEPSSEALGVGEVLHVKTESLAPPLCLLGDDPTSSFETVQINVIPTSDDSSDVQTKIEPVSPCSSVNSEASLLSADSSSQAFIGEEVLEVKTESLSPSGCLLWDVPAPSLGAVQISMGPSLDGSSGKALPTRKPPLQPKPVVLTTVPMPSRAVPPSTTVLLQSLVQPPPVSPVVLIQGAIRVQPEGPAPSLPRPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAVLADNQQLRRENAALRRRLEALLAENSELKLGSGNRKVVCIMVFLLFIAFNFGPVSISEPPSAPISPRMNKGEPQPRRHLLGFSEQEPVQGVEPLQGSSQGPKEPQPSPTDQPSFSNLTAFPGGAKELLLRDLDQLFLSSDCRHFNRTESLRLADELSGWVQRHQRGRRKIPQRAQERQKSQPRKKSPPVKAVPIQPPGPPERDSVGQLQLYRHPDRSQPAFLDAIDRREDTFYVVSFRRDHLLLPAISHNKTSRPKMSLVMPAMAPNETLSGRGAPGDYEEMMQIECEVMDTRVIHIKTSTVPPSLRKQPSPTPGNATGGPLPVSAASQAHQASHQPLYLNHP
The following text describes a protein:
Function:
Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSRIQYVDQVDQVELDQQQQPGSSSTVSGSTPPLQISPHGSPSLQQSQRLGKHLSKSASELNGHDCHLSESPHISPKRAKSAVAQQLAGVSSGGVASGVGVLQKTHGFFNNLRHRWSRAKSKDRLGRKSPSDFLEESTDYAADYSSEGSSVTHSPRHRSTTIGGSPLAREFRATAKMAQVIQRFGGSMEGRIDEHPENGSAGCSPPELSTQQQLEALQANELRRKREAQLRQFVFFQLRVHLKSGSDLVAMDKNGLSDPYVKFKVGGRLLHKSRTIHRDLNPVWDEVFIVPIEDPFQPIIVKVFDYDWGLQDDFMGSAKLDLTQLELGKAEDIHLQLCDSSGNGGSGLGEILINLTLWPRSQEDKEMHFQRNSKLAESSKRLKSQIWSSVVTILLVKAKDLPLAEDGSKLNDTHFKFRLGNEKYKSKSSWTERWLEQFDLHLFDEDQNLEIALWNRNTLYGKAIIDLSVFQRENTHGIWKPLEDCPGEVHLMLTISGTTALETISDLKAFKEDPREAQLLRERYKFLRCLQNLRDVGHLTVKVFGATGLAAADIGGKSDPFCVLELGNARLQTQTEYKTLTPNWNKIFTFNVKDITQVLEITVFDEDRDHRVEFLGKLVIPLLRIKSGVKRWYTLKDKNLCVRAKGNSPQIQLELTVVWSEIRAVCRALQPKEEKLIQQEAKFKRQLFLRNVNRLKEIIMDILDAARYVQSCFEWESPVRSSIAFVFWIVACVYGDLETVPLVLLLIILKNWLVRLITGTTDAAAHYDYEYDEDDDDDKEKEEKKSIKERLQAIQEVSQTVQNTIGYLASLGESTINTFNFSVPELTWLAVVLLLGAILVLHFVPLRWLLLFWGLMKFSRRLLRPNTIPNNELLDFLSRVPDNEEINQYRELPPSAPTDQTRNNPKKKLKGS
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MDFEDGNGKIGNLIVLAFSFIVVAVVIVAFAATYRPYPPGPTFHLSPPPGPPNSPLNSSKSSRKALVPTLPTLDSICMQTDYVSTCRSSLGSVSNGKNLTVKEYLEVAINEAIQDVNEVKELSKQLAASTRTLSDRQALNDCDELLSLGLYELKAAFGVVSNNSELYKQSADVKNWLSAVLAYQEACRDGFKDKKIELTVDNALQNPKQKTSNALAIVDSHLKNPTSPGIISRSLISKDYPLWFSAMNRNLFEGYSNGILQSDAVVAADGSGQFKTIGEALNSYKLNTKGWYVIYVKAGVYNEHVFISRILTNVYMYGDGIDRTIISGSKHTMDGLPAYRTATVAVLGDGFVCKSMTIQNSATSDKETVALRVQADKAAIFKCKIEGSERSLYALAHRQFYRECIITGMKDIIYGDSTIIIQKSSIIVRKSGIPRKFKLVTAQGRTERTETTGFVLHDCTIVQEEEESGKTPTYLGRPGGRYARTIILQSYIGNGIDPEGWIIGFSSREKEIMFFAEFENHGPGADRKRAKLEGYQVITSKSEAVKFTPIHFIQGDLWLPQTGVPFGANLL
The following text describes a protein:
Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs).
Subcellular Localization:
Cytoplasm, cytosol. Endosome. Note=Predominantly cytosolic. Recruited to endosomes as part of the ESCRT-I complex.
Domain:
The UMA domain mediates association with the ESCRT-I complex.
Sequence:
MAARKSGSDIHNNGPVSYLDDVPFKLNEKFRCPSKVGLPIGFCLSDCNAILSDLQYDFNLERRTVQWGEELAKARAAEARAAEAIRTDSESERQAASQDAEVGLVGGKKARPSDEQDIVPPALKPVLAGLSHNAILTPLPAPSFGQTRPAPSNPAPQYLNLADFEREEDPFDKLELKTLDDKEELRTILQSQPQSSVSPPQLPPAEHRPVSPSTTPPLQAKTGIFHKPNGLVGLLDLDRGGVLGGQIDADRPCNIRSLTFPKLSDPGDSPLETPLSVYPVAPPRNLSNGTPPSLQRTASNNNTTLPQEQPVFAQNGTPKQSNPVTVTSHPPAGTTLLSLSPSERQCVETIVGMGYSYEGVLKAMQRQGQNVEQVLEYLFTHSRLCDRGFDATAVEECLEMYQGSEEKALEFLQLMSRFGEMGFERDTIKEVLLVHNNDQDKALEDLMTRATAS
The following text describes a protein:
Function:
Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
Subcellular Localization:
Periplasm. Note=Localizes to the division septum.
Sequence:
MSFSRRQFLQASGIALCAGAIPLRANAAGQQQPLPVPPLLESRRGQPLFMTLQRAHWSFTQGTRAPVWGVNGRYLGPTIRVWKGDDVKLIYSNRLAENVSMTVAGLLVPGPLMGGPARMMSPNADWAPVLPIRQSAATLWYHANTPNRTAQQVYNGLAGMWLVEDDISKTLPIPNHYGVDDFPVIIQDKRLDNFGTPEYSEPGSGGFVGDTLLVNGAQSPYVEVSRGWVRLRLLNASNSRRYQLQMSDGRALHVISGDQGFLPAPVSVKQLSLAPGERREILVDMTNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTDNLPMRLLPTEIMSGAPVRSRDISLGDDPGINGQLWDVNRIDITAQQGTWERWTVRADMPQSFHIEGVSFLIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYYGQPSWPHFPFYFNSQTLEMADRGSIGQMLVNPAS
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of diacylglycerol diphosphate (DGPP) to phosphatidate (PA) and the subsequent dephosphorylation of PA to diacylglycerol (DAG). Together with LPP1, regulates intracellular DGPP and PA levels, which are phospholipid molecules believed to play a signaling role in stress response. Can also use lysophosphatidic acid (LPA) and phosphatidylglycerophosphate as substrates. Substrate preference is DGPP > LPA > PA. Activity is independent of a divalent cation ion and insensitive to inhibition by N-ethylmaleimide.
Miscellaneous:
MISCELLANEOUS: Present with 3038 molecules/cell in log phase SD medium.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Domain:
The phosphatase sequence motif I (including Arg-125) and II (including His-169) are part of the cytoplasmic loop 2 and phosphatase sequence motif III (including His-223) is part of the cytoplasmic loop 3.
Sequence:
MNRVSFIKTPFNIGAKWRLEDVFLLIIMILLNYPVYYQQPFERQFYINDLTISHPYATTERVNNNMLFVYSFVVPSLTILIIGSILADRRHLIFILYTSLLGLSLAWFSTSFFTNFIKNWIGRLRPDFLDRCQPVEGLPLDTLFTAKDVCTTKNHERLLDGFRTTPSGHSSESFAGLGYLYFWLCGQLLTESPLMPLWRKMVAFLPLLGAALIALSRTQDYRHHFVDVILGSMLGYIMAHFFYRRIFPPIDDPLPFKPLMDDSDVTLEEAVTHQRIPDEELHPLSDEGM
The following text describes a protein:
Function:
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Mediates the recruitment of the WASH core complex to endosome membranes via binding to phospholipids and VPS35 of the retromer CSC. Mediates the recruitment of the F-actin-capping protein dimer to the WASH core complex probably promoting localized F-actin polymerization needed for vesicle scission. Via its C-terminus binds various phospholipids, most strongly phosphatidylinositol 4-phosphate (PtdIns-(4)P), phosphatidylinositol 5-phosphate (PtdIns-(5)P) and phosphatidylinositol 3,5-bisphosphate (PtdIns-(3,5)P2). Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Required for the association of DNAJC13, ENTR1, ANKRD50 with retromer CSC subunit VPS35. Required for the endosomal recruitment of CCC and retriever complexes subunits COMMD1 and CCDC93 as well as the retrievere complex subunit VPS35L.
Subcellular Localization:
Early endosome membrane. Cell membrane.
Domain:
The LFa (leucine-phenylalanine-acidic) motif bind directly to VPS35 of retromer CSC; adjacent motifs can act cooperatively to bind multiple CSCs, although there is significant variability in the affinities of different motifs for retromer.
Sequence:
MNRTSPDSERPPASEPVWERPWSVEEIRRSSQNWSLAADAGLLQFLQEFSQQTISRTHEIKKQVDGLIQETKATHCRLHNVFNDFLMLSNTQFIENRVYDEEVEEQVLKAEAEKAEQEKTREQKEIDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANERVDLILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDSEDEKEEEESDEDFASHSDNDQNQHTTQISDEEEDDDGDLFADSEKEGDDIEDIEESAKSKRPTSFADELAARIKGDISNQRKEGQTDGKPQKTVKEKKERRTPADDEEDILFPPPTLTDEDFSPFGSRGGLFSNGQGLFDDEDESDLFKEAPRARPAQAPVSEELPPSPKPGKKIPAGAVSVLLGHPDVSGSTSAPSLKELQKHGQPTPGKSSHLPTPAGLFDDDDNDNDEDDNNFFMPSSSKPSKTDKVKSTAIIFDDDEGDLFKEKAEALPAASVSQTHESKTRADKTIALPSSKNLKLVSETKTQKGLFSDEEDSEDLFSSQSSSKPKSASLPSSQPPTSVSLFGDEDEEDSLFGSAAAKKQTSSLQPQSQEKAKPSEQPSKKTSALLFSSDEEDQWNIADSHTKLASDNKSKGELWDSGATQGQEAKAVKKTNLFEDDDDDEVDLFAIAKDSQKKTQRTSLLFEDDAESGSSLFGLPPTSVPSATTKKESVPKVPLLFSDEEDSEVPSGVKPEDLKVDNARVSPEVGSADVASIAQKEGLLPASDQEAGGPSDIFSSSSPLDKGAKGRTRTVLSLFDEDEDKVEDESSTCAPQDGREKGLKTDSRPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKIRSSVPSGGSLFGDDEDDDLFSSAKTQPVVPEKKGTLKKDHPVSLKNQDPLDSTQGSKEKSTWKTEPAQDSSGLTPFKSREPSSRIGKIQANLAINPAALLPTVALQIPGTKPVSSELAFPSSEPGRSHILESVPTLPGSVEAGVSFDLPAQADTLHSANKSRVKVRGKRRPQTRAARRLAAQESSEAEDVTVDRGPVAQLSSSPVLPNGHQPLLQPRMASGQTSSETATAPPWEGGPVLSAADRSFFVKSRPQTGNEADLFDSGDIFPKSRGSQSVEGAGVMAGEPPSHSSGGRKEKSLAFPDLSEGSSTEDLFQSVKPRAAKNRNPFPLLEDEEDLFADPRGKKNERKPDSHQDSVSKTHDIFEDDIFATEAIKPFPKKREKGRTLEPNLFDDNIDIFADLTVKPKEKSKKKVAAKSMFDDDTDDIFSSGLQAKASKPKSQSAEAASEQRSEHKVASIFDDPLNAFGSQ
The following text describes a protein:
Function:
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including palB/RIM101 itself) and represses transcription of acid-expressed genes (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSHINHLLNSDEAIPSTALRSCAQRSPMSSDDELVGTAGYRENQPVPGSTLPTSPSDVSTDTENDEHQRLLCQWDACGSEFSQPELLYHHLCQDHVGRKSQRNLQLNCHWGSCTTKTVKRDHITSHLRVHVPLKPFSCSTCSRKFKRPQDLKKHLKVHMEDTMKERSRAAPGSRGVRKTGVNKGSALQEKARTLPNLTVESFVSQEMQNYYPYYKSRQHLDETLSHIILPPPAALGGTLASEPPSYTRKAVSFFTTLSQDMSRRLPSLAPCNSPGPAGKMVMLPRPEQQYARVPRYPAMPELPPLVTSPGAESHALPRGHNFRPAPLIPGSMLPSLSRFSHDKSQFVARNSYSLNQKASLNEELCENELDIALENLALDDTDALRAELQTVNIIKDYLTCLLLEDVYTESFELPASVEKSHSTLRKYPQIKV
The following text describes a protein:
Function:
Cleaves tripeptides from the N-termini of proteins. Does not cleave mono- or dipeptides, or N-terminally blocked peptides.
Subcellular Localization:
Secreted.
Sequence:
MRKSSIRRRATAFGTAGALVTATLIAGAVSAPAASAAPADGHGHGRSWDREARGAAIAAARAARAGIDWEDCAADWNLPKPIQCGYVTVPMDYAKPYGKQIRLAVDRIGNTGTRSERQGALIYNPGGPGGSGLRFPARVTNKSAVWANTAKAYDFVGFDPRGVGHSAPISCVDPQEFVKAPKADPVPGSEADKRAQRKLAREYAEGCFERSGEMLPHMTTPNTARDLDVIRAALGEKKLNYLGVSYGTYLGAVYGTLFPDHVRRMVVDSVVNPSRDKIWYQANLDQDVAFEGRWKDWQDWVAANDAAYHLGDTRAEVQDQWLKLRAAAAKKPLGGVVGPAELISFFQSAPYYDSAWAPTAEIFSKYVAGDTQALVDAAAPDLSDTAGNASAENGNAVYTAVECTDAKWPANWRTWDRDNTRLHRDHPFMTWANAWMNLPCATWPVKQQTPLNVKTGKGLPPVLIVQSERDAATPYEGAVELHQRFRGSRLITERDAGSHGVTGLVNPCINDRVDTYLLTGRTDARDVTCAPHATPRP
The following text describes a protein:
Function:
Catalyzes the last common step of the biosynthesis of aromatic amino acids, produced via the shikimic acid pathway.
Sequence:
MASSFLSTKPFLGSSITDDAFSGLRYLPSHLLRSPVHISIRTSTPKKLQIQAAGSTGGNYFRVTTFGESHGGGVGCVIDGCPPRLPLLESDMQFDLDRRRPGQSRITTPRKETDTCRILSGVSEGVTTGTPITVLVPNTDQRGHDYSEMSLAYRPSHADATYDMKYGVRAVQGGGRSSARETIGRVAAGAVAKKILKSLAGTEVLAYVSQVHKVVLPEDLVDHDTLTLDQIESNIVRCPDPEYAEKMINAIDAVRVRGESIGGVVTCIVRSCPRGLGSPVFDKLEAELAKAVMSLPATKGFEIGSGFAGTFLTGSEHNDEFFTDEHGRIRTRTNRSGGIQGGISNGEIIKMRIAFKPTATIGKKQHTVSRDKKEMELIARGRHDPCVVPRAVPMVEAVVALVLVDQLMAQYAQCNLFPINPDLQDPLFSPRLELELEPEPNNVPV
The following text describes a protein:
Function:
Potential transcription factor that may play a role in the regulation of genes involved in cell cycle G1/S transition. May bind to regulatory elements of genes, including the promoter of the transcription factor FOXO1.
Subcellular Localization:
Nucleus.
Sequence:
MLPCFQLLRIGGGRGVDLYTFHPPSGAGCTYRLGCRADLCDVALRPQQEPGFISEVHAELHAERRGDDWRVSLEDHSSQENQTGPDLSTSDPPFVSVVLSGVPPPTGTLVNNVRLPRGHRLELSDGDLLTFGPEGPPGTSPSEFYMFQQVRVKPQDFAAITIPRSRGEEGETRAGFRPMLPSQGAPQRPLSTLSPTPKATLILNSIGSLSKLHLQPLTFSRSGSGPQNPPVSTTPGEVRTTPSAPPPRNRRKSAHRVLAELDDEREAPESLPPVLIEPRKKLLRVEKTPPTPSGNRRGRPRKHPVSIPRAPPAAGGGEPCAAPCCCLPQEETVAWVQCDGCDTWFHVACVGCSIQAAKEADFRCPGCRVGIQS
The following text describes a protein:
Function:
Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
Sequence:
MVEKRIPIQVAEAVERVMKYAKHGEVEEISITESYGRILGEDVVSDHDVPHFDRSPYDGFAIRAEDTKEATQENPVEFEVIGEIGAGSVFLEEVGAFEAIRIMTGAAIPEDCNAVVMLELTEGFEKNGKTYMKLKRPFNNGDNVSFKGEDIKQNQVLVKKGVAINPGVAALLATFGYSTVKVVKQPVVGIVTTGSELLEVHEPLEPGKIRNSNSYMIAAQIMKAGGKVRYYGQLADELDACFTAVQSAMDEVDILITTGGVSVGDYDYLPAIYERLQANVLFNKIAMRPGSVTTVAEVDGKLLFGLSGNPSACYVGFELFVHPIIKTYLYAKEPHVYRADAILQKDFPKPNPFTRFVRANVTIVDGALQAMPVGLDKSSAVSSLADANAFIVLPGGTRGFETGMKVSVLLLEHSEGCEWPWAKPLQSYK
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MANANPTNLVQLYTELNKFINISDYKQALKAANKIIHSKEGKEDVEAMHCKVVCMMQMNQFSEATKFIDATAEIKEFTHSVLVFEKAYCQYRLLHTEEALETISQVKDPDPRLLELKAQVLYKLGQYSEALIVYKNLIKECSDDYEEERMTNISAVHAALSSFDGVKTEMGFPIETYEQLYNKGCWLLGQDKVEEGRVTLVEAERVCREMFEDDPDVAEDEVDGEVSVIRVQLAYALQLQGKTDEALTIYNQVIRLRPTDIALVAVASNNIISINREQNVFDSRKKMKATVAPGLDNKLVPFQKKKINFNRALLFMYSNQWEACRKLLKSLHREHTDTNIPCLIQTAQIGREKGANKAVEYLKTYISEHSDPDLSPEVDLTDVKLCLVQLLMGSGNLSEACEVLESLGSLSYTPALVSCLVSLYGAQHEGEGKATKLMQRAIQWHKKNKSPPSIMTSLMWEASEYSLKHNDPKSAASVLEELLSLDPKNVKVLAKLIFAYSRFNPSKAHQASEDLPSLSDLSVHVDVDDLERNASRITPRYVKKQKEKDVVEVNVATSLVSEGTSNIEIIKTKKRKKKKNPKPQNFRENYTPDDERWLPLRERSYYKGRRKDRKKGGVGKGTQGGANTGVADVYDMSHKTSAAVAPNSPKPGSTGSGSHGNTPINSPKPTHVKGVKGKKSGGGGKKKKKGKGGW
The following text describes a protein:
Function:
Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells.
Sequence:
MPGPRPRKGAQAGGQGVAVAKQLGLFVELSPEDMLLGMEETEDDGDLEAELLALTGEAGTTGRKPAPKEQAPLPMAHIEQLAADCMRDVEEEEEEEGLEEDADLLTELQEVLGADEEAGPLDGSETASPGVPEEEKGQENIEPPVQTALLTASVPAAQAGGPQALQALLEDRIHNYREAAASAKEAGEAAKARRCERGLKTLESQLAAVRKGRKINEDEIPPPVALGKRPLAPQKTTNRSPEADSPGPPTVEPDNPSQPETSLLGSPRISAPPDSDPDPRALLLARQREYKTAALNAKRAGHLDRARELMRTGKKFGAVLEALEKGQPVDLSAMPPAPEDLKLLPQASKAPTAPSVVSPAVERVQPLLAPDTPATPAPTEPQTVLDALQQRLSKYREAGLQARGSGDERKARMHERIAKQYQDAIRAHHAGRKVDFAELPVPPGFPPIPGLEPTTVTEEDAVAATLAAAQKLASSEDAAPAEEDEDENEDESPAQAPVAKKPAQPLVPSSRSLPEPKASSSKESLSPSVREQLAVLETRKLQYQRAALQAKRGQDLEQAKAHMRVAKCLEAQIVQVRAGRPVDLSKVPSPLTDEEGDFILIHHEDLRLSQKAEEVYAQLQKMLLEQHEKCLLYSKQFMHQGNVTETTRFEKLAQDRRKQLEILQLAQAQGLDPPSHHFELKTFQTVSHPAGRQSLEEETFPHCSFSLLPGCRIFSELNSTEMHLIIVRGMNLPAPPGVTPDDLDAFVRFEFHYPNSEQAQKSKTAVVKNTNSPEFDQLFKLNINRNHRGFRRVIQSKGIKFEIFHKGSFFRSDKLVGTAHLKLERLENECEIREIVEVLDGRKPTGGKLEVKVRLREPLSGQDVQIVTENWLVLEPRGL
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
Sequence:
MALTQERKNEIIAEYRVHDTDTGSPEVQIAVLTAEINSLNEHVRVHKKDHHSYRGLMKMVGHRRNLLTYLRKKDVQRYRELIKRLGLRR
The following text describes a protein:
Function:
Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation. Required for NSL complex stability and for transcription of intraciliary transport genes in both ciliated and non-ciliated cells by regulating histone H4 acetylation at 'Lys-5'- and 'Lys-12' (H4K5ac and H4K12ac). This is necessary for cilium assembly in ciliated cells and for organization of the microtubule cytoskeleton in non-ciliated cells. Required within the NSL complex to maintain nuclear architecture stability by promoting KAT8-mediated acetylation of lamin LMNA.
Subcellular Localization:
Mitochondrion. Nucleus.
Sequence:
MGSTSKQTKLVKRLASVSSNLASSAVPSYTDPTTAELPSGKKLTSDPTRPTATTDSCSRCDNSEASESESDYRCESSVEGLPEDEALKRTDVLTLEEVVQRRAKRVRQLMKLYRTQYWGLLEEMRTKYRRFYLRHGKSGWRDDVEGGEREREGPGKPGEDGGDGMREPPERGHVENLHCGAQGCSTKPLPLSVFCFSHILQEPRQRLYKPCSFVIRTGQSGGTTCGRPVLRAVVPPLCGQHFHQAQRQASRSLKKVLPGGPKANPKLHLIITQYVQEIQAKRRAFQKKVALTSQLENGVEVHPGGSGGSLDNALSDHGGQG
The following text describes a protein:
Function:
Beta-mannosyltransferase involved in cell wall biosynthesis through beta-1,2-mannosylation of cell wall phosphopeptidomannan (By similarity). Plays a role in the ability to produce hyphae in the presence of three bacterial species.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MKFPKLRKRTVYWAVLTVFALFTIHFVFQYKEHNSHRVQPIVLIPKAFPSLILNSFDTQNEELVPIKLLKNCQIIRSYHTGYEENTKLLGQEPQSNFHKFNFTVFSSMKPIGLDLKQCQLLSSSSQVEVNDAVNMDASLHDILGKLLQDIRHGKLEYLQEIAPFFLPELQLQLNLNIVDRFWYRFSGSSIWLDQYNMYFMISRIAYSPHGVKNQPVVSLTYGQLFDRNWNEVKNINLLVPSNDPSKNGGHDSFRIISFPYFLPIPFWHDIDNTDGNYFGPEDPRLILVRNKQGYEEPLLIFNSYHRKFVHYDDDEDSIMGQTVKFQRSMFMCWPWQYQMGKSNVEGTSNPEYDNKVYNRVIELKVKLLADMKSQKNWTPFISEDSTNKFDSYIYFVYRWANLDVLKCSLLGDVAGDCVFDYRLDETLVPQNKVGPLRGGTQLVNLRQVIPRSVYHRLLPSHREIFIGFARTHLDNCGCGKVMYRPNLVILVKDAADKTYYKISHISSSLSFDVPIIGWNVYKPDDLCFDSNVLIPYSVSNWNITSLELDIEGGRWVSNDQLTLTLSISDSTVHRLDIRGLFQSILDLADRSLFIPVDRETRVIDEFQNGLQNPGSNPLNQDVNSLGVNNDNIVCALDASVEFCFEYGAKFSIPKQEEFYEVEQQEFNEELIDPKKHQYFKILGKYLYDHASVNS