lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Essential for gut mitochondrial activity. Might be involved in tissue specific growth factor production.
Subcellular Localization:
Mitochondrion.
Sequence:
MNKLLNIAQAGHRQFVREYAFKSDLKIKWMRPEKIACYKPEKSGDLAKLPPLKADELLPEYRDCKELDKADESVKSLFKLSNNASYLTTKFYRDEMVKEVQRHAQDFGSMEAKLAKMTAVIRRYQEHMDKHPRDKMIKVRLKELIDKRKKFLKYLRRWDYPRFEWILEKLDLVYKPPPTHFHWITRKESLQKLTDIYCENLKEERLEAYHKQLQAQQIPFLEEAIKKMQFVRQEQISCDVPVTVTEEKIADSKRQLEMLKELQQAEAAASSKKQNEDGFN
The following text describes a protein:
Function:
A crytic transcriptional activator. When its expression is induced it relieves H-NS repression of the bgl operon. Acts independently of transcription factor LeuO.
Sequence:
MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGNPYKLHTYTSQESFQDAMSRISFAAVIFSFSAMRSERREGLSCLTELAIKFPRTRRLVIADDDIEARLIGSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREILRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCETSNVLHPY
The following text describes a protein:
Function:
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular Localization:
Nucleus.
Sequence:
MDSSESQSQMDDQDARILRLQNLIEKNIEIEQQIENNTIGESITAIEEIIQTANDISKGHEDRRTNSTELVLDTELLRRNFEVVGKAIQHNTNVTDRMVATAINDLVFKESEEDWDALCSLAIQFGRPLFTNDSMLPFIDVTPKVVVQKQRAPRKTKSQVDEKRPEKSDQLERKDEGAASVTHMLKQIRQIYRDGNQEPIPYFKLICNPNNFMDTVQNALQLSFLVKENYISIENGEDGLPLVRVVNSKSVEGNAPSQAICSIDVTFCEKMVKHYNLHEPMLKRLPVSEK
The following text describes a protein:
Function:
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair; Putative 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. May be involved in DNA mismatch repair (MMR).
Subcellular Localization:
Nucleus.
Sequence:
MGIKDLLRFMKPYVEPIHIKNYAGKRVGIDAYSWLHKGAYSCSMELCLDSNSERKLRYIEYFMHRVNLLRYYNVTPVVVFDGGNVPCKAATEKERNKKRNTNRELAMAKLKEGNVNAASELFQRAVNITPVMAHKLIQTLKSENIEFVVAPYEADAQLAYLSNLETEKGGIAAVITEDSDLLTYGCPAVIFKMDREGNGERIELEKVFSAESCKPSFQSFNMKLFTGMCVLAGCDFLPSVPGIGVARAHALVSKYRNIDRILSVLKLEKGDQMPEDYAKSFKDALAVFEHARIYDINTKELKHMKPLPESFLESLDEDLNFLGPEIPSTIVKAIAEGNLNPSTKEAFDKSECSRLPLHPIDPHTIGQLKKSEVPTIKQDNCFSIFGSQNTNKNCTVTRLSDKDKYSNEVTALQKLIMPLETNETMTKPFTFDETHLKVPNNNPFRIRKHEEEISLVQKEETMEEISIVSSGEYIDLNDYMSPINFQEEGSINLLKKRKFENVCLDKVEVTDEQVSGVTEVENCDGLCLNMESQESVKSKIRNSSDLKGSGGSEKKSKKKKESNIRTILSFFSKV
The following text describes a protein:
Function:
May be involved in the regulation of ethylene receptor signaling. Promotes cell expansion and plant growth.
Miscellaneous:
MISCELLANEOUS: Plants silencing SAUR78 exhibit increased sensitivity to ethylene, while plants over-expressing SAUR78 display reduced ethylene sensitivity. Plants over-expressing SAUR78 exhibit increased rosette diameters.
Sequence:
MAKVGKLTKLKSAMKKWPSFAKNHHHSTSSAAVSDELSEDNNLHVVYVGQTRRPYMLRPDIISHPLFQELVDRSSSRSIEQDREIVVACEVVLFEHLLWMLKSGQEGGSVEELAEFYTY
The following text describes a protein:
Function:
Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity).
Subcellular Localization:
Endosome.
Sequence:
MTIKSLLSDIEREERNVHKAIKDSVKRNDLVTAKALAREIVSSRRTVKRLYENKAQVNSISMHLGESIATAVTVGNLSKSGEVMKLVNSLMKAPEIAVTMQAFSKEMTKTGVIEEFVSDAVDNALDSEDIEEEIEEEVDKVLTAIAGETAAELPEAVRKQKMNVPAQKAETLHGEDAIVEGVDAEEELEAIRYRLANVRS
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. A ribosome-associated translation-dependent mRNA interferase. Inhibits translation by sequence-specific cleavage of mRNA. Prefers either in-frame or out-of-frame 5'-AAA-3' codons (lysine). Also cleaves the first three AAAs of stretches of four or more A sequences. 20% of codons containing AA are cleaved and occassionally cuts even at a single A.
Sequence:
MIKSFKHKGLKLLFEKGVTSGVPAQDVDRINDRLQAIDTATEIGELNRQIYKLHPLKGDREGYWSITVRANWRITFQFINGDAYILNYEDYH
The following text describes a protein:
Function:
May act as a serine/threonine-protein kinase and guanine-nucleotide releasing factor.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MNSIHKQHYTINSNHYNESININSLLLNDLNDEKRTTSTNNKSNNNSNNNNNETLEDIIEFNNNNCNGDMKYLDLSKRMIYSLELMMIPEIENRFQGDFKSISILNLNDNLLGEIPESLKQLTQLISLSIRGNHILEIPLWFPEEFKLLRKLDVSHNAISSVPNTFNKFSILEDLNLSNNYISYIHPSLFPEGIMRLNLSNNLFREVELPPWFESLLTLDISGNKLKHLGNLPFHLVRVSIDDNHLESIDHKVILRNKDLALKFNQSFSDIVLERIYQCWYTGDPVLDLSGLGMCVVPPILGMLVHLTHLDLSGNCISVLPPELANLTELVRLDLSFNILTTLPLYIVSYKRLEHLDLQGTLDTLVSPPRRIAETGKLIDIQRYFHDLFQGEPSYRVKLMIVGQENVGKTSLVKCLKMKKKFSKNSDHLGTNVSTDGIDIDEIKFNLDIELPSNPSSNSLISNSLSNSSISSNNINSNNNINVHSNGGGINSNGVNSNSQININSSSGNIHSNGGGVGNVNSSGGIHSNNSSGGGGGSNSFLNNTNSNGTNNNSSNLNINTNSNNVNSSGGGNNYHPPVGTNTSMSNIQVIGSSGSNLGSGSNLSIGGSNGNNNNNSGGSGTMVNQRVTMSIWDCAGQELYYTSHQMFLTDSALYVVVWNLCKPEVNSRVEFWLHSIRSKAENAPILLIGTHLDDYLATHSESELDEILENIYSKYFRKFRLKGISILSCSTGVGFDNFLDLLKKTVVELPSLKQSLPELYLKLEKLIIKKRSTLVPPVLTWQSFSQMVLSNLDFHDEIHVKVATKALVPLGSISFFDEPGLDQYVFLDPQWLTGVFSSIITTKHKFIKDGVLKKSDLYQIWKPPHFIEDEGLHSLLINLLERFELMFPLDSDLVSLSSSNGNNGNSYVNNNNNNNNNSNNNNNGSNKSSPFKTTPSSPSTLRLVDSKSKGSHSSNPILSGNNSSSKNSTSTKRSISGSPLRSRSNSDLDLIGGGGGSPINGSSIDYSSKSNTLTPGLFNELNQKFIIPSQLPEIRPSFGLLWPSLDHSRVEFNRWIQLSFAPAGLFSRLLIRLLISKEFDMKPILYWRNGVVVESQSGKSFLSTSTALIEMVPSYANCSSTIKISVRGDRRTGRGLSAKLLRLIVEIADTLCTSWYHLETNQVIPCPHCINKPNCTLFSLSDCEAVASSGVWYLLCGDRKINFETFVPDVAMSDFWGSGSKKFNYDQIKMHKEKRILSIKPASFGNNQIQFEVRVPPSPPPPPVQQIINNGADDNITTTTLAVNNIKVLESGGSQPPSPRSGKDVTHELPIINRLEIIQPTSDESSLIQVEFDHNNQTLVISGTYKYGDLLEIEFESPKLIGRGASGKIYRANLNDTMVAVKQLEVVGEDAPRIFSEFRREIHVMSDLKHSNVVNLLGFTLSPFTMVMEYIDCGDLHKFLHSPIGDQLNGNWALILKLALDIAKGMEFLHSVTPPLLHRDLKSPNVLLSMKDGVYTAKVGDFGLSSRMFIQALKHKLRNFPVGNITWVAPEILREEEYTVKSDVYAFGLILHELLTRKHPYREFNYSMVSLQEDAIKNGLRPTISPSYTQTVTGHEYCGLIQDCWDSDIDRRPTFNKIVKRIKQIIGRDVNNILMVNGVSVVSGIQSPNSLADSQPFHYHQQQQPSLNSTNQLQQQQYSSVLTSPRSNLSDSSNSSQNIANKSLNNISATSLGDLGGNDENLGGQLQYSMRVPQPEAKVNQLVWEVNSRRVWGGCESGEIIVWNAENGNQIFREQKLHPGPIRSLALVNQEDIWSAGGIGPQQSTIRIWNAWRFNLDDQSGTKSDFITKKGRGGSTFGRKSWRLRWFVLSRFDKTLKYYSKQTDKEPSCSLILEGAWLEEISPPGYKVSLHLIHPEKRTMEMEFKSESEKSSWLTAINRVINQNIPLYEIALGKQMTSGSENDYITNLLSVGPNVWVSLKETPSILVYNVKSKELVTKISLNDDQSSDQWGKTGAVNMMLVNNFVWITGGSKLTQIDSQSYQLLEVHGNHYSKPITSMALVEKNVWISCEDESLSVWDGDTGSFIRKVGSPIGSPTKPTVYTKLLYFSGYVWACTQGSIHIYCIHSLTCKKKVESKNHPNSIVDLIKVFQQTVWSCCGTNNVCIWS
The following text describes a protein:
Function:
Nitric oxide dioxygenase involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the fungus from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress. Plays a role in virulence since nitric oxide is generated by macrophages of the host immune system.
Subcellular Localization:
Cytoplasm.
Domain:
Consists of two distinct domains; a N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
Sequence:
MTVEYETKQLTPAQIKIILDTVPILEEAGETLTQKFYQRMIGNYDEVKPFFNTTDQKLLRQPKILAFALLNYAKNIEDLTPLTDFVKQIVVKHIGLQVLPEHYPIVGTCLIQTMVELLPPEIANKDFLEAWTIAYGNLAKLLIDLEAAEYAKQPWRWFKDFKVTRIVQECKDVKSVYFTPVDKDLLPLPKPERGQYLCFRWKLPGEEFEISREYSVSEFPKENEYRISVRHVPGGKISGYIHNNLKVGDILKVAPPAGNFVYDPATDKELIFVAGGIGITPLLSMIERALEEGKNVKLLYSNRSAETRAFGNLFKEYKSKFGDKFQAIEYFSEDNNTDDKIVIDKAFNRKLTTDDLDFIAPEHDVYLVGPREFMKDIKEHLGKKNVPVKLEYFGPYDP
The following text describes a protein:
Function:
Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.
Subcellular Localization:
Nucleus.
Sequence:
MTFKKEPAASAAAFPSQRTSWGFLQSLVSIKQEKPADPEEQQSHHHHHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSILHQHVQQQPAQHHRDVLLSSSGSRTDDHGNEEPKQDTNVKKAKRPKPESQGIKAKRKPSASSKPLVGEGEGAVLSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEAIAKGAASAEPGSSNHNNMGNLAVLSQGNTSSSRRKSKSKSIAVENKEHKTGKTNESQMSNNINMQSYSVEMPTVSTSGGIIGTGLDELQKRVPKLIFKKGSRKNTDKSYLNFVSPLPDVAGQKSLSGKPSGSLGIVSNNSVETISLLQSASGKPGPISSNYDDAMQFSKKRRYLPTASSNSAFSINVGHMVSQQSVIQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSSKSEPQKEDPFNLTEPRVDLHTSGEHSELVQEEHLSPGTQTPSNDKASVLQEYSKYLQQAFEKSTNAGFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQQKNLESSTSFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR
The following text describes a protein:
Function:
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.
Sequence:
MPFAIGQRWLSESENALGLGVITALDQRTVTIYFPAADETRIYAMAQAPLSRIVFSKGETLSHQAGWQGEILDVQNMNGLLFYLVKNPQDEDVIVQERDISPIISFSQAKDRLFSAQIDRSTHFALRYRTLCHQQAQFKSPLRGLRGTRASLIPHQLHIAAEVGNRVNPRVLLADEVGLGKTIEAGMILQNQLFAEKVQRVLIIVPETLQHQWLVEMLRRFNLHFALFDEERCNDFDLDAVNPFTTESLIICSLNWLETHPNRVELVLNAQFDCLIVDEAHHLVWSETSPSTAYLLVEQLARIIPSVLLLTATPEQLGQESHFARLRLLDPERFFDYQTFVKEQEHYQPVVNAVESLLANKALSAVEKNHISDLLLEQDVEPLFKAIASNNDEEQQRARQELIQALIDRHGTGRMLFRNTRQGVKGFPHRVYHQITLSEENDKIDWLIDFLKLHRNEKIFVICQTAATAIQLEQILREREAIRAAVFHEKMSIIERDRAAAYFADLENGAQVLLSSSIGSEGRNFQFAANLVLFDLPTNPDLLEQCIGRLDRIGQKRDVQVYVPCAKDSPQSRLARWYNEGLNAFEQTCPMGMALFSQFADELEKVRSNSTALSENEFSGLLKQTKTAREKLKIELEKGRDRLLELNSHGGEQAQALADQIADEDNSPELVNFALKLFDIIGVEQEDLGANSIVISPTGTMLVPDFPGLKEEGVTVTFDRELALAREEMEFLTWDHPMIRQGIDLVASGDIGKAAMALLVNKQLPAGTLLIELIYVVESQSPKGLQLNRFLPPTPIRLLLDNKGNNIGEQVAFETLHSKLKPLGKNITNQMVKMARSNIESLIMRGDQLVKSLAEPIIAEAKNQADQQLSAEINRLQALRAVNKNIRQSEIDILEQQRTQSLDELSKANWRLDCLRVIVTNKE
The following text describes a protein:
Function:
Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. The catalytic activity regulates its dynamic association with the 40S subunit. In addition to its role in ribosomal biogenesis acts as an adapter protein by recruiting NCL/nucleolin the to PRMT5 complex for its symmetrical methylation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSDSEGIESYESFLMRKEQASLQEEGANKEDSEDEEQDEDDDWYWDGTDTNFKHYSATRSSNPQANRNNIQSGSSKTYTVSDKVLQKYENKINLGKLYISESVFNKVSEKSRQKESDTYRVKDKSDRATVEQVLDPRTRMILFKMLTRGVISEINGCISTGKEANVYHASTSSGDNRAIKIYKTSILMFKDRDKYVSGEFRFRHGYCKGNPRKMVKTWAEKEMRNLIRLNTAGIPCPEPIMLRSHVLVMGFIGKNDMPAPLLKNAQLSDSKARELYLDIIQYMRRMYQDARLVHADLSEFNMLYNNGNVFIIDVSQSVEHDHPHALEFLRKDCANINDFFVKYDVAVMTVRELFEFITDPSITKDNMDAYLEKIMEIAAERTEEERSSQDKVDEEVFKKAYIPRTLNEVKNFERDVDTMQKLKEEDMSLNTQQDNILYQTVTGLKKDLSGAETVPALLQNSNNEDQLGSDSDDDDDNDDGAKDSASDSDEDIHPKNQGSQPEVDKKERKKTVKEAQREKRKNKVPKHVKKRKEKVAKMKKGK
The following text describes a protein:
Function:
Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in mid-late stages of complex I assembly.
Sequence:
MGSSSAFHIASRDPTKRVCVIERDPGYSKCSSTLSVGGIRQQFSMAENIQLSQYSYKFFTEVSKHLTVDPADPADIHLRRGAYVMLASKEGVSTLMENYKLQRDLGCHIKLLDNHGLHKRYPWMNTDDIKLGSVGFDCEGCFDPWALLSSFKKKSISLGVQYIHAEATGMMVSDDKIAGIQIAPSSQPDARYTLRCDTVVNCAGPWAGRIARQAGIDLPVEPRKRYVFVFKCPDQPIRENTLFVDRTGVYFRPEPQGYICGLSPNEDEEPDVADLEVDYDFFTEKIWPVLAHRVPAFECIKIQGAWAGYYDYNVLDQNAVIGRHPKLSNMIFATGFSGHGIQQSPAVGRAVSELILDQEFTTIDLRNMGYERVINNAPIREKNIV
The following text describes a protein:
Function:
Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.
Subcellular Localization:
Nucleus.
Sequence:
MKQGQGAHLSGQRIGHHPTAQMNPGDGDGNGRHQVASGHASADPELMNLRIRMTNRLIWELLSREPKLQTRPRKLVSDLAKRFEAVIYKKNPNKAAYYSILNGEIFPHLQHALSTHMAQHQQGQQMLQQLTSSSSYGTTIPIPDVVQNASGNTRALYEMDNTSGPMSNGHHHFSANFPLHSTTKGASLEMSAVSMQEGKITHMIPTPGSSNQQSLPGNFHYSTGTGYLNGKSNVMAQMQEQQAPFASKINCCPVQRDLGGYAGSGVHSDILNNSSPYGVSEAHMIDGMGLHRSNVQVINRTVVPETFINPSPYGISPNKPLQRHVNPSTRSTPTPADIAASTSFNGTGSSALSTTSYLDMTTVNSLPKSRMDSGLIMSQPTIQSFQTEYYIQTEGLDLQEKISLEQLHQQVNQLHLIQPHSQYAQNQCSLKLQQQNSLHHLVMSRGNVLTQCHLGSDHAEKLLDKRNQLHSELVSSQINEHVGLTNLQGHYEQTQYHDNYKKGQMSASSQNLGIPAPHDLLPPQQQFDDGSYRLSCFLKETYTKPLQPHCKSKPMKEVIMTSLLSGKIQDGFCQKKMARDREHHPIISGWHSAGCAATSFGSEEVMENTKQYHAQARWLLFLFHAKSCTSPPGSCKSSYCDRVRELVVHLTDCQIKDCSYRHCRESKMVSDHYKNCINEHCHVCCKAKEMLRRSSELAHKQNPAEPILITQHNMNQRSADRVHGDRMDIDQAVETFDDQPPAAKRPKLQLVSPDASENVPVCQKNPGFMLQEAHPRQLDQNKKMVPDQEVDVGLDIRHPQVTLVSCHGSDEKIGAAQNTVIPGALNKIHCHVQQETVVADKESVTVVDVKKKTGSVDVTISKTGKPKVKGVSLMELFTPEQIHEHINSLRQWIGQWVQCDKCECWQHQICALFNARRNDVEEAEYTCFKCYIEEFKRGLRMPLPESVVRGAKDLPRTLLSDHIEERLFKRLREERQERANKLKTSLDEVPGADGLVVRVVSSVDKKLEVKPHFFKILQEDNYPAEFPYKSKAILLFQKIEGVEVCLFGMYVQEYGAECKFPNQRRVYLSYLDSVKYFRPDIETVSGQALRTYVYHEILIGYLEYYKQRGFTSCYIWACPPVKGEDYILYCHPEIQKTPKSDKLRQWYLSMLQKAIKENIVVELTNLYDQFFVTAKECKIKVSAARLPYFDGDYWPGAAEDIINQLQLEGDGKLLKKGRVNKIITKRALKAAGHTDLSGNASKEAMLMQKLGEIICPIKDDLIMVHLQYSCSHCCTFMVSGRRWVCNECKSFYICDRCYNAEQRLEEKERHPSNSKCLHILHPVEIVGVSEDTKDRDIILENEIFDTRQAFLSFCQGYHYQYDTLRRAKHSTMMMLYHLHNPTGPAFVATCNVCNCDIENGQGWDFKSFERKQNQLSESRRMASVNERVRQRVAEVTRHE
The following text describes a protein:
Function:
Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine. L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator. May also act on O-phospho-D-serine.
Sequence:
MSANFSLCKKVPLRMGSLFEMKEKFRSADAVCFDVDSTVIKEEGIDELAKFCGVGDAVAEMTRRAMGGSLTFRAALTERLALIRPSREQVQALITEHPPRLTEGIKELVCRLHQKNVQVFLISGGFRSIVEHVASQLDIPLTNVYANRLKFYFNGEYAGFDETQLTAESGGKGKVIAQLKEKYGFRTIIMIGDGATDMEACPPADGFIGFGGNVTRQQVKEKAKWYINDFEELLRELENSIKMNHNDIIY
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MSRGGRGGFGRGGGRAGGGGSNMPPMGLSFQELGSLDKTPSKLYPEPPTIPRMERPDHKEIRYASYQLMYLQEQKTSAYWPTLEERKQGDLIRFTDRYRPEAQDLPSLKSIHLQKEVFPKGLWDSFMQGETKREEQKAKKKARRKINWDSIELEDRAGADDDIGDASSEPEDLGDYEDEVDDDYAENYFDNGEDDDVGDDEGGEAVY
The following text describes a protein:
Function:
Plays a role in the control of cell shape and motility in the trabecular meshwork.
Subcellular Localization:
Secreted.
Sequence:
PIAITCFTRGLDIRMERADVLCPGGCPLRDFYVFGNTVYASLSSVCGAAIHKGVISSSGGAVRFYGLPGRENYSSVNANGIQSQMLTRWSSSFTITETQTRALEATGRAPATARPATGKRLKKTSEKKMGNKDCKADIAFLIDGSYNIGQRRFNLQKNFVGKVAVMLGIGTEGPHVGLVQASEHPKIEFSLKNFTSTKDVLFAIKEIGFRGGNSNTGKALKHTAQRFFSADSGVRKGIPKVAVVFIDGWPSDDIEEAGIVAREFGVNVFVVSVAKPTAEELGMVQDVSFVDKAVCQNNGFFSYHIPTWFGTTKFVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLDFVARVVETFEISDIGTKVAAVQFTYDQRTEFSFTDYTTKENVLAVIRQIRYMSGGTATGDAVAFTVRNVFGPLRDSPNKNFLVVLTDGQSYDDVRGPAAAAHKAGITVFSIGMAWAPLDDLKDMASEPKESHTFFTREFAGLEQIVTDVIRGICRDFVDSRQ
The following text describes a protein:
Function:
Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
Subcellular Localization:
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Sequence:
MTEAGAKKAAGKKSGKGKGKNAKKNQPNITPVAENRKAKFRYEILDSVECGMMLMGSEVKSMREGKLSLDEAHIRVTNGELWLVGSDIAHYNNAGMWNHDPRRPRKLLVHAKEFDKFAGRAFERGLTLIPLRVYFSERGLAKCVMGLVKGKKLHDKRETIKKRESDRGLQRAMRRK
The following text describes a protein:
Function:
May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.
Sequence:
METSLISPMKENNTAQPQQREENTQQNLNAAVPIKQQSPGLLPEALEVGVKPDPASQILATQEIENPVAGFEGDSDKFHISTDEMAEHLQASDLWYCPDGSFVKKIIVHGHGLDKPKLGSKCRVLALGFPFGSGMPEGWTELTIGTGQWREKTWGELTEKCLESMRQGEEAKIHLPGSSTPLAKLRLDSFTNGRDSWELEAVEKEALAKEEHRRGTELFRAGNPQGAARCYGRALRLLLTLPPPGPPERTILHANLAACQLLLGHPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGDLDKATADLKKVLAVDPKNRAAKEELGKVVIQGKIQDAGLARGLRKMFS
The following text describes a protein:
Function:
May play a role in mitochondrial mRNA editing by facilitating the association of the gRNA-binding (GRBC) complex with the RNA editing core (RECC) complex. However, appears to be dispensable for mRNA editing per se.
Subcellular Localization:
Mitochondrion.
Sequence:
MFRWSWCRLIISKVSAESYVDYLQNSDRELPALSEIFPRHGTGTGELVKFHSLLCEAMKDHNFNYVGIKVVPPTSPPLQCLRATEPVCVPIFSNSFQGSVFSAKQHRIQFVEPLFVIRLGRDPPTQLTANTVPAVCDAFFPGVEFVGSRYPFYPPHTTGFAADLGGCVAVHLGEAVSLGSASLESLGDTNFVVTRREEPIQVGAGKNCLGGPGAAVALAVSYAASMGWPLREKHYIFCSGVGSRSPALAGEYKVNYGAYGSVSASLT
The following text describes a protein:
Function:
Repressor for the uidRABC (gusRABC) operon.
Sequence:
MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLLDLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS
The following text describes a protein:
Function:
Possible transcriptional activator.
Subcellular Localization:
Nucleus.
Sequence:
LVRPPYSYSALIAMAIQSAPRRRLTLSQIYQYVAGNFPFYKRTKAGWQNSIRHNLSLNDCFKKVPRDENDPGKGNYWMLDPNCEKMFDNGNFRRKRRRRGE
The following text describes a protein:
Function:
Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine).
Sequence:
MAAATAENGARHILEIAEGFMKSQVLFTGMKLGIFDLLGTSSAPMTTMGIAEGIGADTDATKRLLDACVGLRLLQKVNMDKETGNGEYQLTKASKAFLTSSSSPNLGDWLGRLAAVYSSPWADLPRAVKEGPNFCTLNGFERGKTFEDLYSTAQYFMGSMEGLTTVFGAGTASAFNLAEFQNICDIGGCTGPLAYHLAAAYPEASVSVFDLPEVVKIAEDRRPTGEYAQRVSFISGDFFQDPLPPADLYVVCRILHDWTEDKVLTLLTKLYDSLPQGGGVLIVEHILTNDKLGPEVAHKYDLHMMVCTGGRQRSGQEFKRLLSSVGFTEVTVKNNTYPFGYVLARKQRV
The following text describes a protein:
Function:
Catalyzes the methyl transfer from S-adenosyl-methionine to the methylene group of 24-methylene lophenol to form 24-ethylidene lophenol.
Sequence:
MDSLSLFCTGALLAGGLYWFVCVLGPAEQKGKRAVDLSGGSISAEKVRDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSHRDATRLHEEMAVDLIDVKPGDRILDVGCGVGGPMRAIAAHSQAKVVGITINDYQVNRARMHNKKAGLDSLCEVVCGNFLEMPFQDNSFDGAYSIEATCHAPKLEDVYAEVFRVLKPGSLYVSYEWVTTEKYRADNPEHVEVIQGIERGDALPGLRSYSDIAEAAKKVGFEVVKEKDLAKPPSLPWWTRLKMGRIAYWRNHILVIVLAAIGIAPKGTVDVHDMLFKTADYLTRGGDSGIFSPMHMILLRKPKEAPSKS
The following text describes a protein:
Function:
Probable transcriptional activator that binds to the DNA sequence 5'-[AG]CCGAC-3' of the cis-acting dehydration-responsive element (DRE).
Subcellular Localization:
Nucleus.
Sequence:
MESYGRKRAWKKGPTRGKGGPQNAACEYRGVRQRTWGKWVAEIREPNKRTRLWLGSFATAEEAALAYDEAARRLYGPDAFLNLPHLRAASAAAAHQRLRWLPASAAAAAARGGAAAVPAYGLLNLNAQHNVHVIHQRLQELKNSSSSPTKPPPRTPTRANPPPPPLPTSSPCSTVTNSVGSAALPPPMSCFQALEQAMAATAAMESAPCDDDAAVVGFGADKPQLDLKEFLQQIGVLKADDDGATGKNGAVHGDDGELADAFGFGGSGEFDWDALAADMSDIAGGHGGALGANGGFQMDDLHEVEQFGGCMPIPIWDI
The following text describes a protein:
Function:
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
Sequence:
MADQGGSNHGIARTSRTRTEEQRQKDLERIKDYRALEDQVRHHAAKNDYSSDVFALTSKLLRLNPEYYTVWNVRRRCLISGLLSKPSPGSSPSKALPTSSPTATTTTSSADFSSSLSTETPPAPESQTTGKSGITAEDDEEQKQQTRQQDQQNDQQILQKELHFTIPLLLESPKCYWIWSYRLWILKQVIERLPVPVARNIWEEELGLTSKMLLRDQRNFHAWGYRRHVVEQLESPELEGKSLVESEFEFTTKKISQNLSNFSAWHSRSKLIPRLLDERNANDEARKAFFEEELNKIGEAINVGPDDQSLWYYHQFLMLNLVNSAEHPTIAPAFTQEERVTYLRREIESIQELLEDYDDAKLIYEALFDYTLYLCQLQGRKPNEQEEKDLKGWLGNLKKLDPMRSGRWADLERDLGLKE
The following text describes a protein:
Function:
Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.
Sequence:
MKQRIGAYLIDAIHRAGVDKIFGVPGDFNLAFLDDIISNPNVDWVGNTNELNASYAADGYARLNGLAALVTTFGVGELSAVNGIAGSYAERIPVIAITGAPTRAVEQGGKYVHHSLGEGTFDDYRKMFAHITVAQGYITPENATTEIPRLINTAIAERRPVHLHLPIDVAISEIEIPTPFEVTATKYTDASTYIELLATKLHQAKQPIIITGHEINSFHLHQELEDFVNQTQIPVAQLSLGKGAFNEENPYYMGIYDGKIAEDKIRDYVDNSDLILNIGAKLTDSATAGFSYQFNIDDVVMLNHHNIKIDDVTNDEISLPSLLKQLSNISYTNNATFPAYHRPTSPDYTVGTEPLTQQTYFKMMQNFLKPNDVIIADQGTSFFGAYDLALYKNNTFIGQPLWGSIGYTLPATLGSQLADKDRRNLLLIGDGSLQLTVQAISTMIRQHIKPVLFVINNDGYTVERLIHGMYEPYNEIHMWDYKALPAVFGGKNVEIHDVESSKDLQDTFNAINGHPDVMHFVEVKMAVEDAPKKLIDIAKAFSQQNK
The following text describes a protein:
Function:
May be involved in the phase-shift of cells from growth to differentiation.
Sequence:
MASTQNIVEEVQKMLDTYDTNKDGEITKAEAVEYFKGKKAFNPERSAIYLFQVYDKDNDGKITIKELAGDIDFDKALKEYKEKQAKSKQQEAEVEEDIEAFILRHNKDDNTDITKDELIQGFKETGAKDPEKSANFILTEMDTNKDGTITVKELRVYYQKVQKLLNPDQ
The following text describes a protein:
Function:
Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
Subcellular Localization:
Endomembrane system.
Sequence:
MGSQGGWGQSKEFLDLVKSIGEARSKAEEDRIVLNEIEMLKRRINEPDIPKKKMKEYIIRLVYVEMLGHDASFGYIHAVKMTHDDSLLLKRTGYLAVTLFLNEDHDLIILIVNTIQKDLKSDNYLVVCAALTAVCKLINEETIPAVLPQVVELLGHQKEAVRKKAIMALHRFYQRSPSSVTHLISNFRKRLCDNDPGVMGATLCPLFDLISADVDSYKDLVTSFVSILKQVAERRLPKSYDYHQMPAPFIQIRLLKILALLGSGDKQASEHMYTVLGDIFRKCDSSSNIGNAVLYECICCVSSIHPSPKLLDSAAEVTSRFLKSDNHNLKYLGIDALRRLMKVNPDIAEEHQLAVIDCLEDPDDTLKRKTFELLFKMTKSTNVEVIVDRMIDYMISINDNHYKTEIASRCVELAEQFAPSNHWFIQTMNKVFEHAGDLVNVKVAHNLMRLIAEGFGDDDEGTDNQLRSSAVESYLRILSEPKLPSMFLQVICWVLGEYGTADGKFSASYITGKLCDVAEAHPSDDIVKAYAVTAIMKICAFEIAAGRKVELLPECQSLIDELSASHSTDLQQRAYELQAVLGLDGHAVESIMPADASCEDIEVDKSLSFLNSYVQQSLEKGAQPYIPENERSGILNISNFRNQDQHESSAHGLRFEAYELPKPSITLRTPAPAPAVSSTELVPISEPTYPKETNQAAKLSTVTDTGATELKLRLEGVQKKWGKPTYSTPVPSTSSSNLKTTNGVNQLGQATLSSHSRDVSYDSKRPQAEISPEKQKLAASLFGGSSSKPDKKPQSTSHKTSRLGNPASEKPQVATASAATTELAPQKTAPVQTPPPDLLDLGEPTVGDTIPSIDPFKQLEGLLGPPDVSSSTNSGTVSVTQPPDLMALYGDSSLSGVSSSISNLVPTNLDSMNLVSSSSSAADHGGSKVALSASLKKGPNPQDSLEKDSLARQLGVTPSIQNPNLFRDLLG
The following text describes a protein:
Function:
Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
Subcellular Localization:
Mitochondrion matrix.
Domain:
Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
Sequence:
MRLKKAARIILVGAPGVGKGTQAERLLQRFPQLSAISSGDLLRDNVKNRTPLGIKAESTIQSGSLVPDAMILRLILHELKTRGWLFPSSTPSMTLASSAAFASSSEFDTDLYVEQPSLAEALSPPQTSNEPSASFILDGFPRTAGQAFQLDSLIPINLVVSLKTPASVILERIAGRWVHAPSGRVYNTTFHAPKVPGLDDITGEKLTKRPDDCEETWKTRLKKFEETSEPLLEHYARKGVLWEVEGNSSDEISPKLYQEFERRFAEI