lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the oleanane-type triterpene saponins (e.g. saponarioside A and saponarioside B) biosynthetic pathway, leading to the production of natural products with detergent properties used as traditional sources of soap. An acyltransferase that catalyzes the transfer of an acyl moiety to QA-triF(Q)RXX to produce saponarioside B.
Sequence:
MEPSKMEVKIISSETIKPSSPTPSHLRKYTLSLLDQKYTPIVVPAILFYERPQGVAPLDMDRLRTCLSQTLTAFYPLAGRAESRDVIICNDEGIPFVEAHVDCELSSVVKSLSSLGSDLRSFYPPRDGLLEGGIQFAIQMNVFSCGGFAFAWYCTHNVTDGTSTANFFRYWTALYAQRSEYAVQDLMDFNSVVTAFPPVPPRVPQEEKPVTTELKPEKQEGQEKEEKKKSSFNFSFQSHIVARSFLIKSKAVAELKAKSVSEEVPYPSRFEAVSAFLWKSIVSSSTTEGKTMINMPVNLRPRVDPPLPLDSVGNIFENALVQSEKKAELHEFVARIRGSISKMKDFATEYQGEKREEAKDAHWKRFIKAVIECKGKDAYVISPWYKSSGFTDIDFGFGTPIRVVPMDDVVNHNQRNTIMLMEFVDSDGDGFEAWMFLEEECIKFLESNPEFLAFASPNF
The following text describes a protein:
Function:
May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MESSSVPPRGVESEAGIKFMKLLEASGPECYASPSWTMNSSREGTLTHSSFLTHTCLRLPCLVVQKQSSQKEPADSPAFISKSCCQESHQDPPKMKGFLFLLFTISLLVMIQIQTGVLGNKTKTMTTTKRPTKGAAPALGSLGGSCVLLFFTNALIRLFHLS
The following text describes a protein:
Function:
Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
Subcellular Localization:
Nucleus.
Sequence:
MAEKTHSKWSLIGNSTNIPNYPTVLPPGMDSVTLQSVLLRAQFEEIQFKLAHLKTEAPRVIQFDEVLSKKNTLVYDQNGYRKDPTQVRARDSLFQERKEVIHAIDSIYPLFRVPGSIRISYKKCTRKFYLPTPNCIGLILGPRGESLKELESRYKVKISIRGQGSTPDSRTTGEVCIPRSPDEPLHALIEADTDSAIDNCISELEMIIMPKPDQENELKKKQLYQLAVYNGVVSADSAFEKKEENENPPWYDPALNLDNSEVRNAVDNFVNDLETKEDETIELEKQKKLEKYKPFMINLRECDISMILPERAPPGFE
The following text describes a protein:
Function:
Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration.
Miscellaneous:
MISCELLANEOUS: Present with 504 molecules/cell in log phase SD medium.
Subcellular Localization:
Vacuole lumen. Cytoplasm. Note=Is released from the vacuole to the cytoplasm during stress conditions like oxidative stress or stationary phase stress.
Sequence:
MLLKNLHSLLQLPIFSNGADKGIEPNCPINIPLSCSNKTDIDNSCCFEYPGGIFLQTQFWNYFPSKNDLNETELVKELGPLDSFTIHGLWPDNCHGGYQQFCNRSLQIDDVYYLLHDKKFNNNDTSLQISGEKLLEYLDLYWKSNNGNHESLWIHEFNKHGTCISTIRPECYTEWGANSVDRKRAVYDYFRITYNLFKKLDTFSTLEKNNIVPSVDNSYSLEQIEAALSKEFEGKKVFIGCDRHNSLNEVWYYNHLKGSLLSEMFVPMDSLAIRTNCKKDGIKFFPKGYVPTFRRRPNKGARYRGVVRLSNINNGDQMQGFLIKNGHWMSQGTPANYELIKSPYGNYYLRTNQGFCDIISSSSNELVCKFRNIKDAGQFDFDPTKGGDGYIGYSGNYNWGGDTYPRRRNQSPIFSVDDEQNSKKYKFKLKFIKN
The following text describes a protein:
Function:
Protein O-fucosyltransferase that specifically catalyzes O-fucosylation of serine or threonine residues in EMI domains of target proteins, such as MMRN1, MMRN2 and EMID1. Attaches fucose through an O-glycosidic linkage. O-fucosylation of EMI domain-containing proteins may be required for facilitating protein folding and secretion. May also show alpha-(1,3)-fucosyltransferase activity toward the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors. However, this was tested with a library of synthetic substrates and this activity is unsure in vivo. May be involved in biosynthesis of Lewis X-carrying biantennary N-glycans that regulate neuron stem cell self-renewal during brain development.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MVRIQRGKLLAFCLCVMATVFLLITLQVVVELGKFEGKKFKNSHLKDGHAQMEAEPLHLHPFFNREGLTLNRKKTLAADSFPIMLWWSPLTGETGRLGQCGADACFFTINRTYLHHHRTKAFLFYGTDFSIDSLPLPRKAHHDWALFHEESPKNNYKLFHQPVITLFNYTATFSRHSHLPLTTQYLEGTEVLTSLRYLVPLRSKNHLRKSLAPLVYVQSDCDPPSDRDSYVRELMTYIEVDSYGECLRNKALPPQLSNPASMDADGFFRILAQYKFILAFENAVCDDYITEKLWRPLKLGVVPVYYGSPSIADWLPSNRSAILVSEFSHPRELASYIRALDRDDRRYQAYIEWKLKGEISNQRLLTALRERKWGVQDVKQDNYIDAFECMVCTKVWDNIRLQEKGLPPKRWQADVTHLSCPEPTVFAFSPLVPRRRSLREMWIPSFQQSKKEARALRWLVDRNQNFSTQEFWALVFKD
The following text describes a protein:
Function:
Acts as an effector of RABF2A and RABF2B. Involved in vacuolar transport of storage proteins. Regulates membrane trafficking to protein storage vacuoles (PSVs). Binds specifically to phosphatidylinositol 3-monophosphate (PtdIns3P).
Subcellular Localization:
Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein.
Sequence:
MATPSSFSSARKKAPSPPKHRHDGTSGLPFGMDWSPPPKRWEGRNTIWPHNPQTGWSYCVMIPSWIAQTPEASATADNFLKSIVFYRIHVGIQSPEGISSSHGVLRRFSDFLKLSSDLKQEFPRKGIPPAPPKHAFSRINSSRVLLEERRNALEEWMQKLLSDIELSRSAPVAAFLELEAAARSYYQDWNQRPSEVGSSAKSSADSSPRPDEHGSGVLSESSQMNSAFAHGNGPTGATGNGMLGESILDQPNERASSMSNHRKKNHVFLEHGVRNGSIDTYKGVVSEEDHDSNPGHARKDSAESIGSDLSSLRGSELSVPGVSSSLWDGPVDLPSGIDGHSQTEQFTGLDMQLLYDMDAQIILPADQRPKLTRLLISMDRRQVTAKTDMEDLIARLNQEVAVKEYLATKVKDLEVELEATKKKDKEILHQAVLTEREKITQLQWDKDELYRKYSEMESNLKIEQNEKTRVQSEKTTASGEKEMLLEELETKRKEVESLQQHIGEFEAKSKADIKVLVKEVKSLRNSQKEMKKVLNQYHEEKTELERIVNREKQRSTRARFSREKILHECRLLRERLQECTAKFVADEQDTMTIDLSSLPDALDLVTTSDNRIRLLVAEAQLLSRDDEQGSSDDGDNSDGKSSVTMSSEDAYVTDEETTKMLSDLLIDNAQLRLRLNSLIRNAVNTAVKTEKEGSDGTVPKKTVLNWLLDR
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane; Peripheral membrane protein.
Sequence:
MELLGSTVTTSCAHPRATPSDFLPAISTMASSYRARFPHYNLAHGLSLPWRPSTYYRVASSLPTLAPYCARSQKVCESTMLPFVSNRTTLFTRYTPDDWYRSNLTNYLESNTSRHNSERLRVDTSRLIQDKYQQTRKTQADSTQNLGERVNDIGFWKSEIIHELDAMIGETNELTDVKKKLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAELLTEVDVILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQAAYQIDDKCHHLRNTSDGVSYFRGVERVDATISVPESWAKFTDDNILRSQSEGAASAKLREDIQNLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQVHLAKLELRRDAHSQLSRAAAHGRFPGWAGKEQGSENHLPIREAEILQEIFQTEMTIESIKKAIKDKSAFLKVAQTRLDERTRRPNVELCRDMAQLRLVNEVYEVDDTIQTLQQRLRDAEDTLQSLVHTKATLEHELAVKANSLYIDQEKCMSVRKSFPNTLRLVGFC
The following text describes a protein:
Function:
May play a role in the organization of actin filament arrays within muscle cells.
Subcellular Localization:
Cytoplasm, myofibril, sarcomere, Z line.
Sequence:
MPQNVVLPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGETRLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHNRRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQNGCSTPSGIDGGSGRSTPSSVSTLSTICPGDLKVAAKMAPNIPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGEAPSMSEPTTTSVPPQSDVYRMLHDNRNEPTQPRQSGSFRVLQELVNDGPDDRPAGTRSVRAPVTKVHGGAGSTQKMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFVEGELYCETHARARTRPPEGYDTVTLYPKA
The following text describes a protein:
Function:
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
Sequence:
MHEVASRPGRFGPYGGRYVPETLMPAVSALEEAYTAAIADPAFWAELNRLHRTYTGRPTPLSFAARLTAHCGGAQIYLKREDLAHTGAHKINNALGQGLLAKRMGKRRVIAETGAGQHGVATATVCALLGLECVVYMGVDDMARQQPNVFRMRLLGAEVRGVSSGSRTLKDAINEAMRDWVTNPDSYYLLGSALGPHPYPTMVRDFQRVIGLEAREQILAETGRLPDVVVACVGGGSNAIGIFHPFLDDHGVALRGVEAGGKGERLGEHAARFRAATPGVLQGTYSYVLQDEAGQIALTHSVSAGLDYASIGPEHAWLHDSGRATYTAASDDEALAAFQLLARLEGIIPALESAHAVAEAIRLAPTMRPDQIILVNLSGRGDKDIFTVAGLLGVSI
The following text describes a protein:
Function:
Catalyzes the NAD-dependent oxidation of L-arabinitol to L-xylulose in the fungal L-arabinose catabolic pathway. L-arabinose catabolism is important for using plant material as a carbon source. Can partially compensate for xylitol dehydrogenase in xdh1 mutants. Also oxidizes galactitol to L-xylo-3-hexulose as an alternative to the standard Leloir pathway for D-galactose metabolism. NADP cannot act as a cosubstrate.
Sequence:
MSPSAVDDAPKATGAAISVKPNIGVFTNPKHDLWISEAEPSADAVKSGADLKPGEVTIAVRSTGICGSDVHFWHAGCIGPMIVEGDHILGHESAGEVIAVHPTVSSLQIGDRVAIEPNIICNACEPCLTGRYNGCEKVEFLSTPPVPGLLRRYVNHPAVWCHKIGNMSWENGALLEPLSVALAGMQRAKVQLGDPVLVCGAGPIGLVSMLCAAAAGACPLVITDISESRLAFAKEICPRVTTHRIEIGKSAEETAKSIVSSFGGVEPAVTLECTGVESSIAAAIWASKFGGKVFVIGVGKNEISIPFMRASVREVDIQLQYRYSNTWPRAIRLIESGVIDLSKFVTHRFPLEDAVKAFETSADPKSGAIKVMIQSLD
The following text describes a protein:
Function:
N-acetyltaurine hydrolase that catalyzes the hydrolysis of N-acetyltaurine into taurine and acetate. PTER also acts on other N-acetyl amino acids (Met, Ile, Leu, Val) and N-propionyltaurine, but at lower rates.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MSSLSGKVQTVLGPIHSDQLGHTLTHEHLSMTFECCYCPPPAPQGALSDAPILMKNLFWVKQNPYSNKENLLLNQEIDAISEELKLFKAAGGGSIVENTTTGISRDVKMLKKLAEETGVNIISGAGFYVDATHSNSTRSMTVEQLTEVLVNEVLQGADGTNIKCGIIGEIGCSWPLTESEKKVLQATAEAQSQLGCPVNIHPGRNSDAPFQIIQILQEAGADISKTVMSHLDRTIFDETKLLEFAKLGSYLEYDLFGTEMLNYQFNQAVDMPSDNDRIKMLRFLINEGYEDRIVVSHDIHTKNRLLKYGGHGYSHILNNIVPKMLIRGISQQCIDKILLENPKKWLTFK
The following text describes a protein:
Function:
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Sequence:
MNILKRKTPQNIRFGEQKPKYYFHIRAFAVLLGVFFLLGVYFNWQSILEKMDDKPISAFALVGQNTFTTADDIKESLLKMGELKGFWGQDVAPIQEQIEALPWVKGAIVRKMWPNRLSIWVSEYQPVAFWNQNQFVTLDGIVFQLPSVRLTAKNLPYLGGPDYQSLKVIETWNQIYINLKSNNIMAKGINIDDRGAWQVQLDNDIVLKLGRGDWKSKLERFVTIYPQIDVPENKKIDYIDLRYTAGAAVGMVDR
The following text describes a protein:
Function:
LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
Subcellular Localization:
Secreted.
Sequence:
MGYLPGIVQLLILQCWCLLIITAMPLDFKGNICSNSNDCNDNTTYIWHQIHNKITELASGARHLFEKYTEVQGLSDKVDQICDPVIVHFPKFNATNSSEKEKAIELFSIFSYVSTALSNITNLQNKISSKKTPLLNELEKTFSGVKGILSNLSCFLCKKYHVTHVSVHYGPPLPSGKLPQKAHGCKVLKKYKHFIHQAVNATIINQLYESGTQNPSVP
The following text describes a protein:
Function:
During development, plays a role in the regulation of the neddylation pathway. Appl and APP-BP1 interact antagonistically during development.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Domain:
The NPTY motif mediates the interaction with clathrin (By similarity). The clathrin-binding site is essential for its association with X11-alpha, -beta, and -gamma. The sequence specific recognition extends to peptide residues that are C-terminal to the NPXY motif. This interaction appears to be independent of phosphorylation (By similarity).
Sequence:
MCAALRRNLLLRSLWVVLAIGTAQVQAASPRWEPQIAVLCEAGQIYQPQYLSEEGRWVTDLSKKTTGPTCLRDKMDLLDYCKKAYPNRDITNIVESSHYQKIGGWCRQGALNAAKCKGSHRWIKPFRCLGPFQSDALLVPEGCLFDHIHNASRCWPFVRWNQTGAAACQERGMQMRSFAMLLPCGISVFSGVEFVCCPKHFKTDEIHVKKTDLPVMPAAQINSANDELVMNDEDDSNDSNYSKDANEDDLDDEDDLMGDDEEDDMVADEAATAGGSPNTGSSGDSNSGSLDDINAEYDSGEEGDNYEEDGAGSESEAEVEASWDQSGGAKVVSLKSDSSSPSSAPVAPAPEKAPVKSESVTSTPQLSASAAAFVAANSGNSGTGAGAPPSTAQPTSDPYFTHFDPHYEHQSYKVSQKRLEESHREKVTRVMKDWSDLEEKYQDMRLADPKAAQSFKQRMTARFQTSVQALEEEGNAEKHQLAAMHQQRVLAHINQRKREAMTCYTQALTEQPPNAHHVEKCLQKLLRALHKDRAHALAHYRHLLNSGGPGGLEAAASERPRTLERLIDIDRAVNQSMTMLKRYPELSAKIAQLMNDYILALRSKDDIPGSSLGMSEEAEAGILDKYRVEIERKVAEKERLRLAEKQRKEQRAAEREKLREEKLRLEAKKVDDMLKSQVAEQQSQPTQSSTQSQAQQQQQEKSLPGKELGPDAALVTAANPNLETTKSEKDLSDTEYGEATVSSTKVQTVLPTVDDDAVQRAVEDVAAAVAHQEAEPQVQHFMTHDLGHRESSFSLRREFAQHAHAAKEGRNVYFTLSFAGIALMAAVFVGVAVAKWRTSRSPHAQGFIEVDQNVTTHHPIVREEKIVPNMQINGYENPTYKYFEVKE
The following text describes a protein:
Function:
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Subcellular Localization:
Cytoplasm.
Sequence:
MDEFEMIKRNTSEIISEEELREVLKKDEKSAYIGFEPSGKIHLGHYLQIKKMIDLQNAGFDIIILLADLHAYLNQKGELDEIRKIGDYNKKVFEAMGLKAKYVYGSEFQLDKDYTLNVYRLALKTTLKRARRSMELIAREDENPKVAEVIYPIMQVNDIHYLGVDVAVGGMEQRKIHMLARELLPKKVVCIHNPVLTGLDGEGKMSSSKGNFIAVDDSPEEIRAKIKKAYCPAGVVEGNPIMEIAKYFLEYPLTIKRPEKFGGDLTVNSYEELESLFKNKELHPMDLKNAVAEELIKILEPIRKRL
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MEEASSSTILEGEITGIKFGLATHQEICTASISNCAISHASQLSNPFLGLPLEFGKCESCGTSEAGKCEGHFGYIELPIPIFHPNHVSELKRMLSLLCLKCLKMKKNKFPTKNAGLAERMLSSCCEDASQVSIGEIKPTDGSCSLQLKRPSKSRTPPGFWNFLERYGFRYGDGHIRTLLPCEVMEMLKRIPQETRKKLAAKGYFPQDGYILSQIPVPPNCLSVPEISDGVSVMSADPSISMLKKVLKQVEIIRSSRSGIPNFESQIVEANELQAIIDQYLQVRGTGKPSRDIDARFGVNKELNASSTKAWLEKMRTLFIRKGSGFSSRSVITGDAFRRVNEVGIPYEIAQRITFEEKVNDHNIRYLQELVDSKLCLTYKDGSSTYSLREGSKGHTFLRPGQVVHRRIMDGDLVFVNRPPTTHKHSLQALQVYVHDDHVVKINPLICGPLSADFDGDCIHLFYPQSLAAKAEVLELFSVEKQLLSSHSGKPNLQLAADALLSLKMMFKKYFLDKAAAQQLAMFASSSLPRPALLKANSAHSYWTAFQILQTALPAHFDCSGDNYLVNKSEILNIDFSTSSVAAVMNDIATSVFFEKGGEDVLKFFDSLQPLLMENLFSEGFSVGLEDFYMSRTSIQDIQKNIQDSSDLLYHLRSTYNEFVEFQLQNRIRSVKVPVSHFILESSALGDLIDSKSDSAINKIVQQIGFLGLQLSDKGRFYSKTLVEDVASLCHSKYPSDIDYPSAEYGLVQSCFFHGLDPYEAIVHSIATREVIVRSSRGLSEPGTLFKNLMAILRDVVICYDGTVRNVCSNSIIQFEYGVNIGSRPQHLFPAGEPVGVLAATAMSNPAYKAVLDSTPSSNSSWELMKEILLCKVNFKNELIDRRVILYLNNCGCGRKYCRERAACLVKNQLKKVSLKDTAVEFMIEYNNQLSGLGSLINDAGLVGHIHLNEDMLRELNIGVHDILQKCQETINSFRRKKVGKKKFNIGYHFKNTVLFASEHCSFHHSCAEKRSDSPCLMFFLQATDDLETTTTLQYYADLICPVLLETIIKGDPRIGSANIIWIDPDTTTWIRSPNKSQKGEWALDIVLEKSVIKQSGDAWRTVLDSCLPVLHLIDTRRSIPYAIKQIQELLGVSCAFDQAVQRLSTAVTMVAKGVLKEHLILLANSMTCAGNFVGFNSSGYKALSRALNIQVPFTEATLFTPRKCFERAAEKCHMDSLASIVASCSWGKHVAVGTGVRFDVLWDTREVELTQEGGLDVFNFLHMVSTANVEEATTGALGAEVDDLMLVDEMADSSFSPELNSSFDRPVFEDLVEFDDKLGDLPEKSNWEKDSSFHTDSNGGKDWSVDKNVGTVAVPDVWSSWGTEKGKTQDSNSAEAQLDSKKSSVLDTSSAWGKNPAKENTTSTWGTTTASENDWCGRGVGEDDSATLSGKKSGVLNTSSAWATNTAREDAASAWGTNPAKENSTSTWGTTRANENDWCGREVGQDDSASLSVKKSSVLDTSSAWATNTAREDAASAWGKHPAKENTTSTWGTTTASENDWCGRGVGHDDSASLSGKKSSVLNTSSVWATNTAREDATSAWGKNPAKENTTSTWGTTTASENDWCGREAGKVEPVDLQPTKPQDDSASLSGWDSPTGDGNSGERNHQWGQHRGDQTKKNRFEGARNWVSSPGEWKNKNRPPKSPGMVNDNSTMGALYTVTRQRLDMFTSEEQDVLSNIEPVMRSLRRIMHQSGYNDGDPLSGDDQSFVLDNVFNYHPDKAAKMGCGIDHLTVNRHGSFQDSRCFFVVSTDGRTEDFSYRKCLDNYIREKFPDLAETFIGKYFSRRGNRERNPTLIQTPTLSQTSTPEQTENAEMQ
The following text describes a protein:
Function:
Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
Subcellular Localization:
Cytoplasm.
Sequence:
MEEELAVNSSHAFSLCQYLSYSRGERASRVETVKDVITQQIKKVKEAHYTKDEVKRMLETTSKLVEIDMNNELINISHNTFLLLRQLMKQAEEANATLKMNLSEIQNIELLKAVAQFEKEIHDKKAERTATILKDPSLLDESIKNLSSDFVSEFYRNDLINLSHALQKSSLEHNTSVNALKQRMLSTEEQLANETKFRSQEHKRISDMEKAHLEMEKRMRDISDQLALKEAELEKKFQSTNTYLNMQKILQSKNAIIQRMRAGNANDDDIEPSD
The following text describes a protein:
Function:
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFVADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNLIKGVSKEVKVRLENVRIQMMV
The following text describes a protein:
Function:
Necessary for centrosome duplication; the function also seems to involve cep63, cdk5rap2 and wdr62 through a stepwise assembled complex at the centrosome that recruits cdk2 required for centriole duplication. Acts as a molecular scaffold facilitating the interaction of plk4 and cpap, 2 molecules involved in centriole formation (By similarity). Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of cep152 can drive amplification of centrioles (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Colocalizes with cdk5rap2, wdr62 and cep63 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (By similarity). Localizes to the deuterosome. Localizes to pericentriolar material (PCM) (By similarity).
Sequence:
MSIDFDSGALQTQQEDEEYDKEDYAREQELQQLLTDLPHDMLDDSLSSSPEPSYSDCSGHEISEKIPQWEHGANWGNDDLPNHQKPYKNGFTENQYCMGFVGKQDEHLRNQAGRDKMSNGWDVLHANEDDPMFNGKYRYSKDHAYNSESNGQAFHGGDHYDAPGHCSSSELYHLPDDFQPYTNCQQVEHFPDSKKEHFQGFAVPEETSKISTEPFQVKYNPYQIKVARMDEMNQDPERRDGNFDDLQREFLDTGENSTGNMQFVQLQVLYKARGRQLEEQNNKLEESERQIRYLNHQLAIVKDQKDGLTISLQESQSLLQNSREMEIQLKGQLTALEKTVESLTTNEEQLRKELNISKVAMESFQQQLLDLRRSESIQRAREQHETVVSMLKKKHEEQVLALQQKLDDVNAMLNEEKELCSRLETRLKLSERKEAESKLEKTDIINRLSKSLEESQKQCANLLQSGSIQEATQLRLQLQQVQSSKIINDGMNKALQEEVRELQEQITMYESAARLGAFVNSGEEQQLSDSYVELGIKNFNWQKSRLGRIVANNGVKNDLSSEEIILELKTELERCLNSNKTKRKQIVQLQAELKGHLLKNEELKKSMEIAERTARDSQIQAENLANKVNNSPFYSSSSDRFREEIQKLQSEKQILQQENEKHLLFIKEFTVNEEKLKASNQELCNEMRGMIQDFDQDKKEAIERCERTYEQHNEDIKAHLLNELYEKFESEKELLSQGYEEKITLLQAQMNEIHREMAAVQECYIAVCKEKDALEENMREHFKKELQKSEEEVTAKAIQDVEMEWAQKLNQALQDAKTKSLQSFETQTIQTDESSLAKSDLNSDCIDELKVKLQNAIQEKEKAVHQAQLELEERHHEETSKQVEVALTRAYGRWLQELTSLPEYKARLKLEQEKWEKTNERNVERQVSDALYAAEIKWKMRSDKVDFTVRQKEFEEKIASMKRELELKAEESQALLKAEIATSRAQWNKEKHDEIQRLREDNEKDYRVFLDEHRNKLTDTLSTAKVEFEKQKNELIAQKDREMAERLDESLKQWALDESRRMRALENEILSEVEQCMYEIHDQLLDKSIVKDRLPSMKSNLDVTFLEKLKACLQKSVKGILYKVLANARQDWKKKYDTESNQETGIRGGELEGSDDRKTAKMWYLDKDLGKTEKQPCCEHWVQQLEKSKKECYEIRSKLEKACRHLQQLVKEQKLKAEKYRKNHILTEELKKQNSELQKKLELTVAPSPACLEPVEGGSNGCMMCNGNALEEIRAQYIKAVDKIKNDMLRYIHESKGRAAELLKSEVLRERQETARKMRKYYLTCLQQLLKDDGNNEGAEKKIINAASKLATMAKVLETPVSQKYQSKSLNSDLPQNENFLSETTQDQRSLQKPAHSHQNNNPLNQNIDQQTIEELIKRHVREKSDGNKVTDAEGASAINENSSFPTLRKSLVDNGNSQFVPSAPFQKLKTFSCIDSSTEGVLVTHQNKQSALQSGTLYPNSEHPKKKPGLQRFDLQETPVRDENGSNDWSCISSKSLFQPHSAKGSLTQLKMGPQNADVEEHSSAVASCSLAEENHNTFSSGARNQHFFAQVAKRKDENSGRKYSNKIQEPSATGIHPESKLFSDVGQGNKLPSRKLLLDFTLSPQQDSGFDSPFPNLNNFN
The following text describes a protein:
Function:
Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.
Sequence:
MRPAVLRTVIRSLPRATAPLAARPVLVRFLSSTLPALKKNKGQNTKTAKQKLRITEDDQAGATDDQGAGEVVIEEVVSKAKAKMEKSVHWAKAVLFEGVERGRGRVSPALLDSVRVSLPDTPGTLHLNALASVTTKGNALFVEVWDTASLKQVESAIHAANLPGISPQRMAGTTLKIPIARPTVEQRAEILRQLAETVEAAKTQIRVARTDGFKALGGRKANGTDEVQKVVDEMCKDLDGQLALAKKEFEKP
The following text describes a protein:
Function:
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
Sequence:
MPFVPTRSLKEKKIDFIEAILNPNAPKGGLYTLERFETLQWQDCLNLSYNDLVECVFERLGLEIPKNLLASALKRYENFDNPKNPAPIFALNERLFVQELYHGPSLAFKDMALQPLASLFSNLAVGKNEKYLMLVSTSGDTGPATLESLAGMPNVFVVCLYPKDGTSLVQKLQMVTQSASNLKVFGISGDFDDAQNALKNLLKDDDFNEALKACQLKLSVANSVNFGRIAFQIVYHIWGFLELYKKGAINSKEKITLAIPSGNFGNALGAFYAKKMGLNIDKIKVVTNSNDVLREFIETGRYDLTHRSLKQTYSPAMDILKSSNVERALFSLFGFERTLELMQALEEEKFYALKPKELALLQEHFSCASCSDEACLKTIQEVYAEHQYLIDPHTATALNASLKTHEKTLVSATASYEKFPRITLLALNEQKKNDNDKAALETLKNSYNTPDSQRLDDLFERGIKHQEVLKLNEIKSSILLWLESLH
The following text describes a protein:
Function:
Methylates ribosomal protein L11.
Subcellular Localization:
Cytoplasm.
Sequence:
MRFKELILPLKIEEEELVEKFYEEGFFNFAIEEDKKGKKVLKIYLREGEPLPDFLKDWEIVDEKITTPKDWIVELEPFEIVEGIFIDPTEKINRRDAIVIKLSPGVAFGTGLHPTTRMSVFFLKKYLKEGNTVLDVGCGTGILAIAAKKLGASRVVAVDVDEQAVEVAEENVRKNDVDVLVKWSDLLSEVEGTFDIVVSNILAEIHVKLLEDVNRVTHRDSMLILSGIVDRKEDMVKRKASEHGWNVLERKQEREWVTLVMKRS
The following text describes a protein:
Function:
May affect the rate of fibrils formation.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MRSACLFLLLVTACWALPFRQSGFLDFMMEDDPGSGVTEVPEGRGLPDVDLGPDCPFMCQCHLRVIQCSDLGLKKVPEKIPKDTSLLDLQNNKITEIKENDFKDLQGLQTLILVNNKITTIHPKAFSSLGKLQRLYLSKNLLKDVPVNMPKSLQELRIHENEIVKIKKASFQGMSNVIVMELGSNPLKSAGVEAAAFADLKKVSYIRIADTNITEIPKGLPSSLSELHLDGNKITKVTSDRLKGLKNLAKLGLSYNEISSVENGSLANVPHLRELHLDNNALTSVPPGLPDHKYIQVVYLHSNKIAAVGTEDFCPPNFNTKKAMYSGISLFSNPVPYWEVQPITFRCVFDRTAIQLGNYRKKSRRSS
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MNLNSLDLNLLTALDALLREANVSRAAMRIGLSQPATSHALQRLRDIFGDPLLVRTGARMELTPRAQALRAPLAQALDQVRGLFVPDEFDAARSERQFRLMMPDLAVELLMPPLMEKVTRAAPNVRVDVVPWRGPAIFHAEFARTIDLVISIGNAFKGFHRQLLYTDSDALAVRRGHPMGAKLKRRETFLAARHVGVIIRGNSEDLIDTWLRAKGIERHIALVVSGYLEALHVAARTDLVAFVPRRLIAALSRQLGLDTVTPPLDPGIDEQFMFYPTRAQMDSGSIWLRRLMLETGRELEKRRAG
The following text describes a protein:
Function:
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesion synthesis (TSL), in conjunction with the beta clamp from PolIII (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MPGKSRIIFHIDMNSFYASVEMAYDPALRGKPVAVAGNVKERKGIVVTCSYEARARGVKTTMPVWQAKRHCPELIVLPPNFDRYRNSSRAMFTILREYTDLVEPVSIDEGYMDMTDTPYSSRALETAKEIQSRLQKELLLPSSIGIAPNKFLAKMASDMKKPLGITILRKRQVPDILWPLPVGEMHGVGKKTAEKLKGLGIHTIGELAAADEHSLKRLLGINGPRLKNKANGIHHAPVDPERIYEFKSVGNSSTLSHDSSDEEELLGVFRKLAASVSDRLQRKEVMASKLFIMIRYADWRTITRSTTLRNPIDQKNDILKEAEHLFFKHWNKNPVRLLGITGTDLVEKEQAYKQLDLFSFNEDAKDEPIQQMMEKLNKKYGTKLIRKGATLKKEESKTKGTSFNKDFFQDEKKS
The following text describes a protein:
Function:
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
Subcellular Localization:
Chromosome. Cytoplasm, cytoskeleton, spindle. Nucleus.
Sequence:
EKVYQECQQEGPITFQQCIPPDKMKLCKKIGEGTFGEVFSTTNSKKETVALKIIPIAGHQKVNGEDQKTFAEILHEVIISKELSSLGEKENNQTEGFITLNNLHCVQGSYPEQLLKAWDKFDRERTSENDRPDFFGSDQLFLILEFEFGGSDLENMKGKLSSLVVAKSILHQVAAALAVAEEALHFEHRDLHWGNVLVKPTKEKEGKYTLNRTPGSFETSGVHVNIIDYSLSRLEIDGLTVSCDISSDEELFMGKGDYQFEIYRKMREENGNIWSDYNPHTNVLWLHYLSDKLLQMTYKRKATTNPLKKMKASLVQFHREVLQYQSATHVLQNCSLFQ
The following text describes a protein:
Function:
Probable sugar transporter. Even if its physiological substrate is subject to discussion, it is able to transport glucose and fructose. Does not transport galactose, 2-deoxy-d-glucose and xylose.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Sequence:
MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEKEETIDAGPPTASPAKETSF