lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Cell adhesion protein.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MNYRIFLLFCTTTVLWSVVSTQLVLGKPPIFQNTGPVEQKVAVEGEIVRLKCDDAELAEQYEWRVGDASGDLIAASRFAQVTVSRTNDNQKYRCVARNTVGAAISPPSVVRSKYLDDFDASDESAQYDVLAGIGRHFVLRTPRLLSSRNLDISYSWIKDDSNQVTPDATHFVTANGDLVVTSVKRDDFGTYKLMASSDDLKEIVSKEYIVKDNGMAPSLQNTLSIIYFSPERTIVESSMPHDEKFDCVTSFEAKDDVRIRWFLNGQPITGSEVGIKTTMNNRRLIISNPSGFTRGEHKLECRADAAMGRTSDQNSAYLTFISRPVLKDLPNEIHKKVGSSLTLKCGVKKKSSMDIKWYRNGLMMNTQRGKLTIDRIRQEDFGLYQCEAVNEAGADMSSVWVKEGDINNDTMVMGMSEDGRSLEEEISMETPPPRKLKFFDSSKSQEQLFPFTSDIESSQRLTKTPKDLTAASGTDKITLECAAAGSPPPHIVWFLNGNGIQTDSVKYDFSNGDLTIHDIRKSDEGEYTCEISGTDVKASANVQVNGDSLIEYGPADQKSLIGTNVEFSCEVAKEYARKATVEWYLNDALLPVNGNSGLRISRNRKGSLIIRQVGPDNTGEYRCRVTVDGREENASAMLQIIEKPAMPERVRAELHNETMPAKVRVRWNEGFDGNEPIIKHAIEIRTMGPTGLWSDWTTAIDNIPKDDGKPCCWADIEDLRPSSTAEFRVVASNKHGPGKPSLPSSSVTMPQQPPSAAPRNVAASARSPHSVMVQWQQPKEEQDSGDFLGYVVRYRLAGYSSLTWNEKNLTTKDARNTLVDELITWREYEIQVAAYNKRGLGVFSESIEVTTAEGRPTQAPKNVRVKVLNSTAVSLEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLSTVVNELEKFGHYNLTVLCFTTPGDGPKSNILRVVTEEDTPEAVDELSIAEVMYNGAVLTWNPPMKENGIVTKYTIRHWASSSPDVKTKHEVDGSTTNITIDGLQPSTRYGVDVMASTKKGDGPVEETKFESGVPPELPGRPSMLSIGDISATTVQLHFTPGFDGHTAIRQWIVEGKMADSSVFAHIFNVSSPKARSIIVTGLRPFTQYQLRLIAENVKGRGAPSEPSRTFETLQTNPETPSQRLFTEPVSATSISVSWTPLLATHWNGQPKGYLIVYREVDEDNWKEVRTPALRSSEHTVTDLRPFTTYEVNVFSENVFGRSLPTDAVKARTYESVPSGSPRNIVVTAEGSKSAIVKWDPVAELSTNGDVIGYKLRVVPERESLMADETREIDVPGQSTLMTKVSNLRPFTSYYVYMSAYTIVGNGPENSTPLSFETLEDVPAPPESFQCSQISEQDVRMKWLPPGSPNGKITNYVISYWKSHEPRSMAIDAQVAGNLLMFSAMSLSPNTQYTFAIKAKNSKGESEEAVAEVMTSSVRLPVRNAPAPVRDTTSQHLATEITIRWDESLPRKLTEDAESPVRAVQVSYQKTNEDEWLTLEKKFEYSKRRAVIKHLSPNSMFRFRIRFIGDFLESSWSPESEWMRTLPSAPFAQPISLKATPYERNSVQLEWVVPHKSTWNSDAIGYRIHYREYPSNETWQMEEIAVHDPHEDREEKVLAKLSTFRHYIIRMRLFNSEGEGPFSAPVFVYVGYSIPKRNLTNIITEPLSSSSIRVKWDAWPKEDSETVTSFKVRYVPVASVLSSVSSEEEVMIVDTNECILSDLRKFAEYQISVSPYNRAGEGKMSQVREKTLEDKPGPVGVLRFSDVLMDSVKVSWDEPAQPNGMVIGYIVNYKGYRMQEEFKNEDQQRTSRNYFDSHGLAEGVTYFFSVWAETSAGKGELRSANVTIGPSKDGPLPPSKPQITSGQSYVTLSWNDVANSDEIVGHLLQAKRVSVAEETENGYVSQRPRRNEIRGAKSAAQTSASSNSNRPTHPIGEWITLRPTDGKSEKEQVSYRELQPSSFYVFRVFTRNVRGIGRASPETEQLFVPESIPDDPFYTTWWFMALVAMAAFVLIVIIIAILCVTGSSAKYRREKRSRSIDSLQLADGNFASFQLKGTSAANMTRSRELPTRPGTTQSWLSDQSREPPAYGSVLGDGRNNGGVMNMYGLATDVIPPLPNSGPPHASLEAMQKLSALVGRDIRSQNTAYVVSSSARGSDNERNEYMPTRSDLYGTRSEYGRVEYRGHIPSSSGGSQPQGSPQQQQEPYDSFDEEDDVDDDTVIRGDRTMTDGADDIARHYGSTDQYRDTWRKVRDTDMVRAPILTNQQPSSAAGRSSTTDSTSEGPWANIPATPNLTAGFSSFV
The following text describes a protein:
Function:
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
Sequence:
MSDIIHLLPDSVANQIAAGEVIQRPASVIKELVENAIDADAQNIHVLVTDAGKTCIQIIDDGKGMSETDARLSFERHATSKIREAADLFALRTMGFRGEALASIAAVAQVELKTRLESEELGTKLVIAGSKVESQEAVSCSKGSNFSVKNLFFNVPARRKFLKANSTELSNILAEFERIALVHPEVAFSLYSNDSELFNLPVSPLRQRILAIFGKKLNQQLLNIEVNTTMVKISGYIAKPETARKKGAHQYFFVNGRYMRHPYFHKAVMEAYEQLIPVGEQVSYFIYFEVDPANIDVNIHPTKTEIKFENEQAIWQILSASVKESLGKFSAIPSIDFDTEDMPDIPAFEQNLPPAPPKIHYNSDFNPFKVSSGGSGGGSYSRPKVEWEGLYGGLTKASKMNEPQQEPEMDWENSPFEEEPMVAEEKTISAVSAASSTFSSASSTLYANESVIEKGNLHLQFKGRFILTSVKSGLMLIDQHRAHIRVLFDRYMVQIKQKQGVSQGVLFPEILQLPASEAAVLQGIMDDLSAVGFDLSDLGGGSYAINGIPSGIEGLNPVELVRNMLHTAMEKGNDVKEEIQNILALTLARAAAIVYGQVLSNEEMVSLVDSLFACPSPNYTPDGKTVLTTIKEEDIEKLFK
The following text describes a protein:
Function:
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for neuroblast specification.
Subcellular Localization:
Cell membrane. Cytoplasm. Nucleus.
Sequence:
MAGNIVKWWKHKILGGYKQFSVQECTTDSEELMYHQVRASSSCSAPPDLLLVSERDNNIQLRSPVVNIITTPPGNASGAGSKQQSHHQTNHHSSGRSHPGHTAHPQDVSSGGSHSKHLRISSTSNGKHGKYSNMQQQLPQDEDVVDAAATMQQQQHTGHAHSRHLHHHKEERIRLEEFTCDVSVEGGKSSQPLQFSFTFYDLDGHHGKITKDDIVGIVYTIYESIGKSVVVPHCGSKTINVRLTVSPEGKSKSQPVVPVPVAAGFSSSHASKLKKLPTGLAAMSKPLAGGGVGSGGASALTTSAGNRRQHRYRPRKLIKSDDEDDDSNSEKEKDAAHAPAADQPSGSGTKATGKSHHHQSQSARYHQKNNSRAEQCCTEQNTPDNGHNTYENMLNLKCCKPEVDQVDCPSHRQHHQSHPNHQMRQQDIYMKQATQRVKMLRRARKQKYQDHCLETRQRSLSVGNDSACPNRHLQLQQPPVGHPQPQSLNHKSASGSPPLGVGGGGDMMLDGVQLRQPRPHSLTPHQHQQQNQQQQQQQRKSAECWKSALNRNDLISIIRESMEKNRLCFQLNGKPQANVSPIRQPAAQQQPQQQQRQRCNTGSKIPTLITNHSPVAQQSPLSCSPPTAEPTTPSIPAAPPAIEVNGQQHHPTHPTHPSHHNHHEHPQPHIPIYHQQLAINPAVLAAQQTHNTAHNKLNLCGYDSFLHATICGGGAAAHSPPATPSNVATVQPIPKKSQKNLLQGYQRLEQSQQQQQQQRSSKDYKNYGNLIYAKLSEQLQQKDREQRRQRHKQQQHQMLQDQPKDASRSEQRPPTSNSSSAGSKIYGDAVECAHLLASEEEDLPPSPQLTSTPSKVVSTDTLIDLNDDVGEAVAEAVTEGGKQSLEAEESGQQVEVELDTSASSSMIHRYVHEHIHHHYHHFKEQQDV
The following text describes a protein:
Function:
Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine.
Subcellular Localization:
Cytoplasm.
Sequence:
MDHVNGESGFHHYDVGIPDDVSPNNQPQIKPNLPFERAAGLVRRLYDFQDVVCLKEFISYYNQNILIEARRPDCAPGSPPKKFVMKLTNSEESQLFVLHQQQNEILLMLRDCGIPCCSPLKNVAGKDLSSEKLSFKHRDTGDTMTGQFITRIMKYIPGQSLGNAPHVTSKMCYKSGQLLGQLSSALQNNTIDKNESIKRAKELIWCLSNVPRLREYVFVLQNSAQKKVIKEIIDAFEEKVLKTEHKLRKGMIHSDFSDYNVLVRETSEELDDDNDNVRGDVVGIIDFDHMMYSCIVYDIAIAIMYLMQCTNLELDPVECGGILLAGFLSKRALSEDEWRVLYYCVAGRFAQSLVIGLHTHSLQLQNDYILSSQRVGWQVIFDFWERDVHDVYARWRELIQHYNQVPKDQPFDTSVQ
The following text describes a protein:
Function:
Involved in extracellular lipooligosaccharide (LOS) biosynthesis and virulence expression. Involved in the synthesis of the oligosaccharide moiety of the LOS molecule by adding GalNAc (By similarity).
Sequence:
MHINYVISLTSAYQRREHIQKEFSQQNIPFEFFDALKPSKELTSLIEKFIPNLLHAKLTEGEKACFMSHYMLWQKCFSEDLPYIYIFEDDVLLGENADKFLAEDEWLEEAFKQTDKFILRFETFLNFSKCKDKKIKPYSGRKILKLVSENCGAAGYVISREAVKQLSAHICSLTSNHLLAIDLLMFNIFNQSTYQVSPGVCVQEGQLYPKDIKLHSQLETERQKYLSVKKKRTLKTVLISLAGKPKKILRKIYRKLFISKHIVPFR
The following text describes a protein:
Function:
Superoxide dismutases serve to convert damaging superoxide radicals, a key form of ROS, to less damaging hydrogen peroxide that can be converted into water by catalase action. Degrades host-derived reactive oxygen species to escape innate immune surveillance. Involved in the occurrence of miconazole-tolerant persisters in biofilms. Persisters are cells that survive high doses of an antimicrobial agent.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Sequence:
MKYLSIISIVALALAGDSPISTDSKGKAPLVARFKKTSKSDIEGTIKFEPANNGTVLVSVDLTGLPSGVGPYPYHVHEKPVPESKNCTATGMHFNPFNGSTTAKTPAALELGDLSGRHGNITSESFEVEYDDSYISLNKDSKAYIGGLSIVVHSNNNTRLNCANITTLDEGDDTASAATWSNSSSSSSSSSKNSTNGSSGSSTSASQGSGAGRAEISGFLAAGIAGVVAALI
The following text describes a protein:
Function:
Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise function is not known.
Subcellular Localization:
Secreted.
Sequence:
MEGKTVIFSVLVMGLVISQIQVEAQKTCCPSQSTRKEFEDCISEGNLQILCSAESGCRDTYVGYCPSGFPYGSLTNSGDVVNVYCKLGCVSSLCGALTSLQKLDTSGKVNVAVERCTKACSTICTKGSKTAVETV
The following text describes a protein:
Function:
Receptor kinase that detects X.oryzae pv. oryzae protein Ax21 to promote innate immunity. Following X.oryzae pv. oryzae protein Ax21 detection, undergoes cleavage, releasing the processed protein kinase Xa21 chain; The processed protein kinase Xa21 chain released by protein cleavage after X.oryzae pv. oryzae protein Ax21 detection translocates into the nucleus where it can bind and regulate WRKY62, a transcription factor. Confers resistance to the bacterial pathogen X.oryzae pv. oryzae (Xoo).
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MVALSLPSRGLTGVLSPAIGNLSFLRTLDLSSNGLSGGIPASIGNLRRLQTLNLSDNALSGELPANLSSCTGLTVMAIRLNRLQGRVPSELGDKLASLRVLDLRNNNLTGTIPVSIANLSSLSYLSLAFNQIQGNIPDLDGILGLKGLDLAYNSLSGALPSSIYNLSSLQMFQIQGNMFHGGIPADFGSRFPGMRILDFSRNQFTGPIPASFSNLTNLQFILLSSNRLTGYVPPTLGRLQALQGLYLYNNRLQADDEAGWEFIASLSNCSQLQQLTLDSNAGLTGQVPSEIGNLPTTLQVLLLDDTGISGRIPSSIGNLAGLQVLNLDNTSITGVIPESIGKLGNLGVLHLYNTGLSGCIPSSIGNLSNLFQLSAYNTSLEGAIPASLGKLTDLQSLDLSMNRLNGSIPIEIFRLSIISMYLNLSHNLLSGFLPAEVGKLSNLNILDLSGNKLSGGIPDNIGECIVLQGLWLDNNSFEGSIPQSLNNIKGLTTLNLSMNKLSGKIPDTIGSIRNLQQLYLAHNNLSGLIPAVLQNLTSLSELDLSFNNLQGEVPKEGIFRNLSTLSITGNNGLCGGIPQLNLDPCHTSSIKKNTKGWLKSLTIALATISAFLFLAFMIALIRLKGNKLRRRKKSPFLPPITDEQYERVSYHALANGTNGFDEVNLLGKGSFGAVYKCTFQDEGTIVAVKVFNLEQVGSTRSFVAECEALRRVRHRCLMKIITCCSSINHQGQEFKALVFEYMPNGSLDGWLHPKSETPTQTNTLSLEQRLHIAVDIMDAMDYLHNHCNPPVLHCDLKPSNILLAEDMSARIGDFGISKILPECASKTLQNSNSTIGIRGSIGYVAPEYGEGSSVSTLGDVYSLGILLLEMFTGRSPTDDIFRGSLDLHKFSEDALPERILKIADTTMWLHTDAYEALQEVNTTRSRIENCLVSIIALGISCSKKQPRERTPIKDAVTKMHAIRYSYKKLLNSNMEQQ
The following text describes a protein:
Function:
Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRKMLLGRMKRCLPICSCCFLQAAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGTLLFIIGLIGCCATIRESRCGLATFVIILLLVFITEVVVVVLGYVYRAKVESEVDRRIQKVYKTYNGTSPDAASRAIDYVQRQLHCCGIRNYSDWENTDWFKETKNQSVPLSCCKASASTCNGSLAHPADLYSEGCEALVVKKLQDIMMYVIWAALTFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus.
Sequence:
MKQIQEKIIVYLKLSMRFLPYSVLVSQIILEYIYQRDEYQSNYLMEHQLIYFVNEKLIDILQIQGVHLVEFIIKIQMNNNRRRQSHSAERVNQQSSIKVQSEQKPPFLLDLQNEMEYIEDILILMARINRTQFQEPQQLKHALKTQNSVYLNILQLIMNVIDPYLEIKSFSDEKFQLLLKRLGYPCKHMSKTRFMSLGSSHTYLQSLHILSWLCRQAQQIIQINERIENGQYQPIEIENESFSNKIKKKLAEYLQDGYIGTIDDSALEKCYRDAKQKLTLELMQLQKDISKLTCELNVIKTQEPNLPEIEEQYKNLDAELMQVTQETQENQQILESTRQEINQNMNKYLEVDNEIIKVHKLIESKRQYIAQQPIKIDKAKEMEAKDYQLTIQSQQLLNELQKYQKELDKARQEKTEMLCKISNIIQMLNSGRVKFDKDYETFEKNLYSYQQKLEQNNGIQIGEDENLLDMELDAQFEQKLANEQVDYKSRKSLVAYDLIQKQDTDSILKLLLPNKEQILQDLNQQLQDILNKLSVSKKQALEMKNELNQKLKQLEDIECAKKMIIQEISQLNDSTEELKVLKQIYLEHQEKQQILLKEMEQKKLEIKFIVDRKNLDVIEIDRLKKQNQENQEVILIMQQQAEIIEEKNTALQQQFKDWVKDNLDQFLSLIQEVKI
The following text describes a protein:
Function:
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Sequence:
MTLTASSSSRAVTNSPVVVALDYHNRDDALAFVDKIDPRDCRLKVGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASGGARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLVDLGMTLSPADYAERLAALTQKCGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKAINASLQRSA
The following text describes a protein:
Function:
Hydrolyzes cerebroside sulfate.
Subcellular Localization:
Endoplasmic reticulum. Lysosome.
Sequence:
MSMGAPRSLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSPLLLGTGKSPRRSLFFYPSYPDEVRGVFAVRSGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVAGATPEVLQALKQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCPDPHA
The following text describes a protein:
Function:
RNA-binding protein that regulates alternative splicing events.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MVLVTAHEYTSGASLPSMSPSLDMLTQTPNNHQAVAVGADPQSTQTDLEPDGAGGAAGVVLTGAQVANAANAVAVAAAAGAAEAAKNGQPKRLHVSNIPFRFRDPDLRQLFGQYGAILDVEIIFNERGSKGFGFVTFATSADADRAREQLNGTVVEGRKIEVNNATARVQTKKTPTIPNVAALRGVAIQRGRARGAAAAPFAAAFARHPSPLTAAAAAASALHGYTPVYQDPFLAYAGAERYQLPVSGVPSLLRLSLCVLPQQATYAASAAYTAAAARSYAAAAAAAQPAVASYTAVAGYGREYADPYLGHSIGPVAGYGTAVYRSGYNRFTPY
The following text describes a protein:
Function:
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Sequence:
LLQVIVIPHSHNDPGWLKTFEGYFLSNTAHILNNMVDFLTKNRDFSFLWAEVCFFSRWWRSLQNRPHLRDAVRRLVHRGQLEMVTGGWVMTDEAAAHYFAMVDQLVEGHQWLRTNLGVVPRNGWSIDPFGHGATMPYILQASGIRSTFVQRTHYAWKQFLAARRQLEFLWQPPFLTSSQRMSSRRNNSSGVLCHMAPFELYSIKHTCGPDPEVCLKFDFRRMAGEYTESRASIINPNNVAELAKELLGQYGRIGSLFPHNVALVPLGDDFRFDRDAEWIQQHKNYRRLFDYINTNSKKLHANVRFGTLQDYFQEVHRRMEKMVSSAAVRGSSLGTPSYWTGYYTTRPYLKHFCRELEHWLRAAEIIYSLARSYLHQTHMKELAERMDAEYVFLVQSRDSLGLFMHHDAITGTSKEGVMTDYGSRMFNGMKEAMGVVAHAAQFLLLLENPQPTQSFEVLPSKVPLTVPGVIGRKVVLYNSHAQHVQEVVRVHVKTLVTKVTSPSNSDIPFQINPVWDDAAMMSTEVFEVVFIAELQPLSLTAYTLYSDVGARNRPAKTRVSLFVADAWAGSDAESIFAFESPASETIELETPYLKASFSHQTGLLTSIRLTESGIENQLNLTFSAYRSLEFHSGAYLFQPDASNPFINVTGRFPIVRVIRGPVASEVMVAYPQIVVHTFRVYHVSGALGGGLEMITLFDLQRHEEMNVELFMKLDTNINSDRTFFTDASGFQMMRRVTNVELPIEANYYPITSAAYLEDKTSRMTLVVSHAHGAASIQPGSLEVMLDRKLRYDDSRGLGEGVMDNR
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MMFLFVSLFMFIFKWQRLIFILISLEFMMLSLFLKFSYVLGEMMFFYFMCFSVISSILGMVVMVGNMKFFGSDNCIF
The following text describes a protein:
Function:
Catalyzes the NAD-dependent reversible oxidation of D-threitol. Involved in the degradation pathway of D-threitol, that allows M.smegmatis to grow on this compound as the sole carbon source. Does not catalyze the oxidation of xylitol, L-sorbitol, and L-sorbose.
Sequence:
MTQAQELSVDFDFRLDGKVALVTGAASGIGAAIASAYATKGARIAAVDLNAEGAEALAAQLGGDRGAHRGFACDVADAASVQAAADAVAAEFGRIDILVNSAGVARLAPAEELSLQDWDSTLAINLSGTFLMCQAVGKRMLEAGGGAIVNMASQAATVALDQHVAYCASKFGVVGVSKVLAAEWGGRGVRVNTISPTVVLTELGHKAWDGPRGDALKKLIPTGRFAYPDEIAAAAVFLASDAAAMINGADLVIDGGYTIK
The following text describes a protein:
Function:
Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MAARDVVVLGGGISGLTLAYFLRQALPKAAADATRIRVLDAGPVPGGWVHTAKRDGFLFEEGPRGFRPSRNGAEMLRLVEQLQLQSRMQAVDPAAHARFILRHGKVEKVPGSLLEALRWPLSLPVARAALHELFVKPGTAEDESVYQFMARRFSPLVAERLLDPVASGIFGGDIRKLSMRSCFAMLVDMERKHGSVVKGMLFGGTGDDTLLDGTNKSDFVKKHDKSVSVSFTDGMSTLMDALADSIENDPMAELQLNTKVTRLAVHGLDNASSKAPSFVVESKDPTSGEYREPIKASHVFSTIPACYLAPAVKDTAPGLAEALSEIKFVDMGMVHVGYNDKVLSTEGFGYLIPTAEREKILGVVFDSNTFPVQNAEGKTQTRLSVMSGGAHFREVASLPEGELERNALDALNRHLGITCEPDYVRAMTIKNGIPQYHVGFAQTLQRIEKQAARSAPGLFLGGNSFYGIGLADCVTHSKQLALKFAKIASS
The following text describes a protein:
Function:
Can hydrolyze glycol chitin and chitin oligosaccharides (e.g. N-acetylglucosamine) (GlcNAc)4, (GlcNAc)5 and (GlcNAc)6. Hydrolyzes N-acetylglucosamine oligomers producing dimers from the non-reducing end of the substrates.
Sequence:
MSSTKLISLIVSITFFLTLQCSMAQTVVKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATTATTRTIQKV
The following text describes a protein:
Function:
Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
Subcellular Localization:
Secreted.
Sequence:
MVWSPVLLGIVVLSVFSGPSRADRAMPKLADWKLCADEECSHPISMAVALQDYVAPDCRFLTIYRGQVVYVFSKLKGRGRLFWGGSVQGGYYGDLAARLGYFPSSIVREDLTLKPGKIDMKTDQWDFYCQ
The following text describes a protein:
Function:
Low-affinity proton-dependent nitrate transporter. Not involved in dipeptides transport, but has a weak glucosinolate transport activity. Involved in phloem loading and nitrate remobilization from the older leaves to other tissues.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Localizes at the plasma membrane, where it interacts with NLA.
Sequence:
MVLEDRKDGSSLPGRSGSFSKSSPSELDVVDPYKRISSPGSILDAEKVEKKPGGWRAVSFILGNETLERLGSIGLLANFMVYLTKVFHLEQVDAANVINIWSGFTNLTPLVGAYISDTYVGRFKTIAFASFATLLGLITITLTASFPQLHPASCNSQDPLSCGGPNKLQIGVLLLGLCFLSVGSGGIRPCSIPFGVDQFDQRTEEGVKGVASFFNWYYMTFTVVLIITQTVVVYIQDQVSWIIGFSIPTGLMALAVVMFFAGMKRYVYVKPEGSIFSGIAQVIVAARKKRKLKLPAEDDGTVTYYDPAIKSSVLSKLHRSNQFRCLDKAAVVIEGDLTPEGPPADKWRLCSVQEVEEVKCLIRIVPIWSAGIISLAAMTTQGTFTVSQALKMDRNLGPKFEIPAGSLSVISLLTIGIFLPFYDRVFVPFMRRITGHKSGITLLQRIGTGIVFAIFSMIVAGIVERMRRIRSINAGDPTGMTPMSVFWLSPQLILMGLCEAFNIIGQIEFFNSQFPEHMRSIANSLFSLSFAGSSYLSSFLVTVVHKFSGGHDRPDWLNKNLNAGKLDYFYYLIAVLGVVNLVYFWYCARGYRYKVGLPIEDFEEDKSSDDVEMTSKKSMK
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Involved in plant response to pathogen infection by increasing PAD4 expression in absence of EDS1 up-regulation.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSTVYVLEPPTKGKVIVNTTHGPIDVELWPKEAPKSVRNFVQLCLEGYFDNTIFHRVIPGFLVQGGDPTGSGTGGDSIYGGVFADEFHSRLRFSHRGIVAMANASSPNSNGSQFFFTLDKCDWLDKKHTIFGKVTGDSIYNLLRLGEVDTSKDDRPLDPAPKILSVEVLWNPFEDIVPRVLAKTSEESAAEIKEPPTKPVKKLNLLSFGEEAEEEEKELAVVKQKIKSSHDVLNDPRLLKAEASDKERNASESKEVLSVREALNAKKEAAQKDKSFSVSDTVGNSDDDDDGEDETKFDAKMRNQVLSRRKEIGDTPSKPTQKKKSSSLKGREESTQRSDAVSSEDEKPRMEKLSLKKKGIGSEAKAEHMEKGDTDLQLYNASERARQLHKLKKRRLQGNEDSVLAKLEKFKQSISAKPFTSSNEPVVLTSSSEPVDNKEEDLSDWKNVKLKFAPERGKDKMSRRDDPDAYMVVDPLLEKGKEKFNRMQAKQKRREREWSGKSLA
The following text describes a protein:
Function:
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTVPTTDAQGLTQFKEPFTFDSVLGLLSKVPFSTPFLALLPALAVLYHKHTNPAVVLPTTHTDALALVRSLLFSQHRWLGYLWIFILIRTINRGLNRYVRNHKEWRRDPIDYTKDVVVITGGSQGIGKEIVQLLSHKKHASIAVLDMAPPAYVKAPAGAPEIVYFKTDVSNREQVGEVGAKIRAAFPGKKIGVLINCAGVASGNTILDVDLESAARLWRINTLANWITAKEFAPDLIARNHGHVVTVSSAGAYATLPSMSEYATSKAAALAFHECLAIEFRTRYNAPRVRTTLVAPTKVRTALGDGMEDHADPFFTPVLEPVQVAEKVVWSLDSGLSQHLLLPGFANLLPWIRALPDWFRRLLAILDNSDNTVTHKSMARALKNGYGSNWEGSDKELHERRLKLLAQQSAPK
The following text describes a protein:
Function:
Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage.
Subcellular Localization:
Lysosome membrane; Peripheral membrane protein; Lumenal side. Lysosome lumen. Cell membrane. Cytoplasmic vesicle. Note=Localized not only on the inner side of the lysosomal membrane and in the lysosomal lumen, but also on the plasma membrane and in intracellular vesicles.
Domain:
A C-terminal internalization signal (YGTL) appears to allow the targeting of plasma membrane proteins to endosomes.
Sequence:
MVGAEPSRPPGPPSYWTGRRGQGLAAIFLLLVSAAGSEARTEDDFSLVQPLVTMEQLLWVSGKQIGSVDTFRIPLITATPRGTLLAFAEARKKSASDEGAKFIAMRRSTDQGSTWSSTAFIVDDGEASDGLNLGAVVNDVDTGVVFLIYTLCAHKVNCQVASTMLVWSKDDGVSWSPPRNLSVDIGTEMFAPGPGSGIQKQREPWKGRLIVCGHGTLERDGVFCLLSDDHGASWHYGTGVSGIPFGQPKHDHDFNPDECQPYELPDGSVIINARNQNNYHCRCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGALATSSGIVFFSNPAHPEYRVNLTLRWSFSNGTFWQKERVQLWPGPSGYSSLTALENSTDGKKQPPQLFVLYEKGLNRYTESISMVKISVYGTL
The following text describes a protein:
Function:
Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the dehydration of 2-methylcitrate (2-MC) to yield the cis isomer 2-methyl-aconitate. Could also catalyze the dehydration of citrate and the hydration of cis-aconitate (By similarity).
Miscellaneous:
MISCELLANEOUS: The prpD2B2C2 operon is essential for growth on propionate as sole carbon source.
Sequence:
MINHEVRTHRSAEEFPYEEHLAHKIARVAADPVEVAADTQEMIINRIIDNASVQAASVLRRPVSSARAMAQVRPVTDGRGASVFGLPGRYAAEWAALANGTAVRELDFHDTFLAAEYSHPGDNIPPILAAAQQAGKGGKDLIRGIATGYEIQVNLVRGMCLHEHKIDHVAHLGPSAAAGIGTLLDLDVDTIYQAIGQALHTTTATRQSRKGAISSWKAFAPAFAGKMSIEAVDRAMRGEGAPSPIWEGEDGVIAWLLSGLDHIYTIPLPAEGEAKRAILDTYTKEHSAEYQSQAPIDLARSMGEKLAAQGLDLRDVDSIVLHTSHHTHYVIGTGSNDPQKFDPDASRETLDHSIMYIFAVALEDRAWHHERSYAPERAHRRETIELWNKISTVEDPEWTRRYHSVDPAEKAFGARAVITFKDGTVVEDELAVADAHPLGARPFAREQYIQKFRTLAEGVVSEKEQDRFLDAAQRTHELEDLSELNIELDADILAKAPVIPEGLF
The following text describes a protein:
Function:
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Subcellular Localization:
Secreted.
Sequence:
MGSPVLQLYVVLCLGASLGSGSPIMSLEVSPLEEDLPLLDDVFSEQDGVDFTTLLESVKNEFLKTLNLSDIPLHNSAKVDPPEYMLELYNRFATDRTSMPSANIIRSFKNEDLFSQPTNFNGLQKYQLLFNVSIPHHEEIVMAELRLYALAQWSHLLYDGVERKVTIFEVQENEGEERKMLVLVSGEIYGTSSEWEAFDVTDAIRHWRRSGSTTHRLEVHIESRNEGAESSERSQPEIDVSAQNKHVPLLIVFSDDQSNDKKEEKEELSDMIDHEDLLELDNLDTDNFHDGPGEEALLQMRSNIIYDSTARIRRNAKGNYCKKTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCSYPLAEHLTPTKHAIIQALVHLKNPQKAAKACCVPTKLDPISILYLDKGVVTYKFKYEGMAVSECGCR
The following text describes a protein:
Function:
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Sequence:
MANSGQYSRERKISNQYDPEQEEYIRKWIEDVIGESLPNGKFSVVLKDGVILCNLINKLSPGSITKINNTKMPFKQMENIAKFIEATNKYGVPSRDLFQTVDLYEARNMIQVLRSLEALGRQAQKLGYDGPTIGAKMATENRRSFTEEQLKQSDAVISLQYGTNKGANQSGMRFPSAA
The following text describes a protein:
Function:
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MTLKPNPSPRRLPPPSRSSAMAADGSVLRRLYFSVYNWVVFIGWAQVSLSMILALLDDGHEAVYAAIERHLLFAQTAAIMETHSHILVTPLIISWSITESITSWKIYYNSLQVIRYSFFGIKESFGFTPSWLLWLRYSTFIVCYPVGMVSEVGLIYIAFPFMKVGPPHDTGEKLKEEGDPIHRTGCRHAARPTPSAIISEALPLHESSPWS
The following text describes a protein:
Function:
Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis (By similarity). Counteracts the production of type I interferon by interacting with host IRF3 component and preventing its translocation to the host nucleus.
Subcellular Localization:
Host Golgi apparatus membrane; Single-pass type III membrane protein. Host endoplasmic reticulum. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Sequence:
MLQLVNDNGLVVNVILWLFVLFFLLIISITFVQLVNLCFTCHRLCNSAVYTPIGRLYRVYKSYMRIDPLPSTVIDV