lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
Miscellaneous:
MISCELLANEOUS: [Isoform 3]: Has antiviral activity against RNA viruses.
Subcellular Localization:
[Isoform p56]: Nucleus, nucleolus. Cytoplasm; [Isoform p30]: Cytoplasm.
Domain:
The ubiquitin-like domains are essential for its antiviral activity.
Sequence:
MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALELLTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKKERPIILDPADPTLNVAEGYRWDIVAQRASQCLKQDCCYDNRENPISSWNVKRARDIHLTVEQRGYPDFNLIVNPYEPIRKVKEKIRRTRGYSGLQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDTLILSKKKGEALFPAS
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. Acts as an essential integrator of the JA and ethylene signal transduction pathways. Activates the expression of the PDF1.2A gene.
Subcellular Localization:
Nucleus.
Sequence:
MEYQTNFLSGEFSPENSSSSSWSSQESFLWEESFLHQSFDQSFLLSSPTDNYCDDFFAFESSIIKEEGKEATVAAEEEEKSYRGVRKRPWGKFAAEIRDSTRKGIRVWLGTFDTAEAAALAYDQAAFALKGSLAVLNFPADVVEESLRKMENVNLNDGESPVIALKRKHSMRNRPRGKKKSSSSSTLTSSPSSSSSYSSSSSSSSLSSRSRKQSVVMTQESNTTLVVLEDLGAEYLEELMRSCS
The following text describes a protein:
Function:
Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.
Sequence:
MQRKIQGNLIIIGGAEDKKNGKDILKEVCKKIDKEKEELLIATVASELPEELGEEYTNIFKNLGVKNVKILNINNRKDTHYEGNVNLIKNASLIFFTGGDQLRITSLLGGTPLYRALERAYKEGCIFVGTSAGASVMSDTMIVSGLDDESPRKCTLKMAPGLSLIRGVIIDQHFAQRGRIGRLLTGIAENPQWLGIGIDEDTAIIVNPEGQFKVIGSGAVYIIDGTEISGTNVSEQYPDEILSIFDVKLHVLKNRDKFDLNYRRPI
The following text describes a protein:
Function:
Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MMRRSSSRNKQRSSGIFVDDEGNPLVFTVTLGVHHKHVCAGIQDNGGVVDPEALEPFMNLVGIYHPTTNPNTFQCCYIDDCIQAGCLLPSDPYIIPTTSARIIHRVQFNEQDDRLLYEMLAKNKGKHFKGNDLYQDFAAQHPRHTWKAWRDRAVKKIIPRMSPQLEGANEDKMDARMTRSAIRRATQIRLQLNGNDPTSISATAHDHGDSHHGLLVQKAESSFKCQLPTSELKRPTIKKLRGPLSRRKHTFFEDAADSNDQNVHSLSFLCRTNDVGFNLTSKITAENYSTFAQKDEQSGRDAHRLDVTPKDNHFVAFEDVTRSPHHRHVMNMPQESQLDEGHDSSESSFEVGETSGMDRLEHSDDSESDVQDKFSSPCPVYKSTKQNAPDDSDKENVVEKRMDEMSAKAMFFSDVNALLAEAIEANYCKRDVMRALMMSSGLIEHARRLLSVQFNISLLEETTRQWIFTSKDDKRLFSGNAIDLERVEATKSSQSIERRVQFLSES
The following text describes a protein:
Function:
Histone demethylase that demethylates 'Arg-3' (H4R3me) of histone H4 with a specific activity for H4R3me2. Involved in the positive regulation of gene expression. Together with JMJ22, positively regulates seed germination by promoting the removal of repressive histone arginine methylations (e.g. H4R3me2) at GA3ox1 and GA3ox2 to trigger gibberellic acid (GA) biosynthesis.
Subcellular Localization:
Nucleus.
Sequence:
MGIQIIGQIERINGKELSYGDFAERYLAKNQPVVISDLTEDWRAREDWVSENGNPNLHVFATHFGKSRVQVADCDTREFTDQKRLEMSVTEFVEQWTNKDSIEESVLYLKDWHFVKEYPDYTAYQTPPLFSDDWLNVYLDNYQMHEDRDSFQKYDQISCSDYRFVYMGGKGSWTPLHADVFRSYSWSANVCGKKRWLFLPPPQSHLVYDRYMKNCVYDIFEEVNETKFPGFKKTTWLECIQEPGEIIFVPSGWHHQVYNLEDTISINHNWLNAYNLSWVWDLLWKDYKDTEESIEDIRDICDDFEAICQRNLAANTGMNLNDFFLFMSRFSLGNMVLLQSYSDKHKNLNSCSLAMAQNLLMNLSTILKVMMKMISAGGVTAEEVYLDLRETLEDPQFLRFVRDMGRTYARIHMEEEDQFLSSKELLQKLSGLAGPNMQICSPKDLVEMINHHNTFSSQIYFI
The following text describes a protein:
Function:
Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass type II membrane protein; Intermembrane side. Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MSLRESPFPNGFLEGLHAVGWGLIFPCFWFLDRLIAVCISTTLERMWRLEQECYLHPLKVVFGSILFFILFVISTPFALLGFILWAPLQAIRRPFSYHKQEQSIPMENRNARWEEMGKISFGFLTANVCLLPDGIARFNNLGHTQKRALIIGKSIVQGVTRPHIRIFVDSPSSCGTVTPSSSLIPQPNASSYGSVDASGELPDAIEVNEITPKPNCNQNSNHQKHPPRSLRTLLRDADIPMEVSALFPPSVDIVCLQEVFDKRAARKLTQALGPLYGHVLYDVGVYACHPAGSCSSFKFFNSGLFLASRFPIMEAEYRCFPNGRGEDALAAKGLLTVKVDIGLQKGEKRMVGFINCTHLHAPEGDGAIRFEQLNMLSKWTSEFQTLNRRDDELPLFDVLCGDFNFDNCSPDDRLEQSHSVFDEYTDPCRAAAGKEKPWVIGTLLEQPTLYDENMRTPDNLQRTLESEDLRKDFISPPVALDGVPLVYPEADQPWIGRRIDYLLYREKSGHRTEVEELTYVTQLAGLTDHIPVGFRLSVSLDSEQN
The following text describes a protein:
Function:
Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB (By similarity). May interact with the HLH region of TCF3/isoform E12.
Miscellaneous:
MISCELLANEOUS: [Isoform 1S]: May be a partial isoform 1.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Translocated to the nucleus, when associated with TCF3/E12.
Sequence:
MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFENFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWLQALQDNCSKEQLWMFSCLIPGFSAPQSEYGPRTLDNLINPPLSLQETQVTIEEVTPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSFLFSHFKKFYLPYIFPNICKENSLYHPVLDIPQIRPKPHYVMIKKDAETNETIYCTKEPFIQARVIVIRWLVSFWLEPKPHSGPNIPGMEGEVLPKNIQRAAASLVSREESKNDTVDKVDKSAEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFLLPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEDTAITCSDIPCSETVADHDSAIEDGEKREEENGTSTSEHVRNSSWTKNGSYQEAFHVCEEATEQNIQAGTQAVLQVFIINSSNIFLLEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMSSQAFLQFQGKKSMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELATEWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEDTGNEVFGALHEEQPLPRSSSTSDILEPFTVERAKVNKEDTSPKLPPLNSETGGNSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPVDDPGVPSEWTSPASAGSSDLMSSDSHSDSFSAFQCEGRKFDNFGFGTDIGIPSSADVDLGSGHHQSTEEQEVASLTTLHLDSETSSLNQQAFSAEVATVTGSESASPVHSALGSRSQTPSPSTLSRAHIEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNAIMDPEIHAQVFDYLCELWQNLAKIRDNLGISADNLTSPSPPVLIPPLRILTPWLFKATMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCSPQFFSLGLPGATMLIMDFIIAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELPALHPNIPDIAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESHHPQIKEALNVICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIHQPQSPLKIIQILIATITHLLPSTEASSYEMDKRLVVSLLLCLLDWIMALPLKTLLQPVHATGAENDKTEKSVLNCIYKVLHGCVYGAQSFSNPKYFPISLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQQGLISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFFVLNNTTLVSCIQIRSEESMPGGGLAAGLVSANSNVRIIVRDLSGKYSWDSAILYGPPIVSGLPEPTSFILSMSDQEKPEEPPTSNECLEDIAVKDGLSLQLRRFRETVPTWSTIREEEDVLDELLQYLGTTSPECLQRTGISLNVPAPQPLCISEKQENDVINAILKQYTEEKEFVEKHFNDLNMKASEQDEPTPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKYSILTNIGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQKNRSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRSTAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHFPADADH
The following text describes a protein:
Function:
Part of the yehABCD fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Probably involved in the export and assembly of fimbrial subunits across the outer membrane.
Miscellaneous:
MISCELLANEOUS: The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MLRMTPLASAIVALLLGIEAYAAEETFDTHFMIGGMKDQQVANIRLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNPQETCLSREVIKRLGINSDNFASGKQCLTFEQLVQGGSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYLSQYYSDYKASGNNKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGVWKSNTLYLERGFAQLLGTLRVGDMYTSSDIFDSVRFRGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVTIEQNGFVVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQPGVSKYDLAAGRSHIEGASKQSDFVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGAGWNTRIGAISVDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRTFNDHVWANNKDNYRRDENDVYDIADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLWRDYWGRSGSSKDYQLSYSNNLRRISYTLAASQAYDENHHEEKRFNIFISIPFDWGDDVSTPRRQIYMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSHQHQGNETTAGANLTWNAPVATVNGSYSQSSTYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDAYVNGQKYRTTNRNGVVIYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVLVNFDTDQRKPWFIKALRADGQSLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVNVAIDKQQGLSCTITFGKEIDESRNYICQ
The following text describes a protein:
Function:
Thermostable endoglucanase that has high activity with soluble polymeric substrates containing beta-1,4-glycosidic bonds, such as carboxymethyl cellulose (CMC) and barley beta-D-glucan (in vitro). Has no activity with cellobiose and filter paper. Has no activity with substrates containing beta-1,3-linked glycans, such as laminarin. Likewise, lacks activity with xylan, galactomannan and pectin.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MNKWHINKWYFFVGMLVIFAVIISLILKDTSLTFSSYDREKFPHLIGNSMVKKPSLAGRLKIIEIDGRKTLGDQHGNPIQLRGMSTHGLQWFPQIINNNAFSALSKDWEANVIRLAMYVGEGGYSTDPSVKEKVIEGINLAIKNDMYVIVDWHILNPGDPNAKIYSGAKEFFKEIASKYPNDLHIIYELANEPNPTESDITNDIAGWEKVKKYAEPIIKMLRDMGNENIIIVGNPEWSTRPDLAVNDPIDDKNVMYSAHFYTGSASVWENGNKGHIARNIEKALENGLTVFVTEWGTSEASGDGGPYLNEADEWLEFLNSNNISWVNWSLANKNEASAAFLPTTSLDPGNGKVWAVNQLSLSGEYVRARIKGIPYKPISRETMGK
The following text describes a protein:
Function:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Subcellular Localization:
Nucleus.
Sequence:
MDTLEPPLLQPSSDLVMQLHDNLHGALINGMLSNGNENGFVDPRVLISTEDAEIAYDNLEPDDEMDSSSSEDTKIIATPRKAYLPTGCCYDDRMKLHAIGDFSDNTPHPEDPRRIEAIMRAFKEAGLLYTGSPEDVDRILKESPTKYMLRIPARVASKDEICTVHYAGHFEWVESLSKKTSEDLRELNTIMDAGRKSLYVGLCTFEAALISAGGAIETCKNVVEGHVKNAIAVIRPPGHHAEANESLGFCVFNNVPVAAKICMLDYPKLCRKVLILDWDIHHGNGTQNMFYEDPNVLYISLHVYENGNFYPGQPDDPDLPDGGIDKVGTGAGIGKNVNIGWPSQGMGDGEYMAAFQKIVMPIAQEFDPDLVIISAGFDAAAGDELGGCFVTPGCYSHMTHMLMSLAGGKVAVCLEGGYNLKAISRSALAVAKTLMGEPPIRQPIPPLNRVAAEVFEEVKYYQSPYWECMRSGVIDYKEAKFKGATRLDDIVRNYQSNVLSKNYQMVSLWVQRHQLARSFDHQVMVTPYIKSATRILLIVHDPPELLATPDPFTAKVELHNSYLVDPVTEYIAWAIENKIGVMDINIPLNTDTFPPATGGYNPRSGVFELESQIQDLVGYIWDNFIQLYDSDNIILMGVGDSYLGIKQLLTIRDCRPRIAGVLAFITGSLRPVKSETDSTLSSWYKSNSEIYVADKHACWNDEESIRKVRKQRFGNVVRSEETGLVKMLQRHQSSAKSWILGKFEEKAKDDEVMTMEDEVSVADVDGAKKLTMGDMQLM
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MERRSSWKPAKQWRKAANVIRTCHRLSGGIQPYVAIDIGNESDSDYSSGNGTSAFTALAADESFRGLVKDKREGSFRRLGGVAGIAAALASDAERGIFPGDVRRRQAAFGVNACPKTSSRPKSRFLSHLQDALSDAFLVVLLVCAAVSLGFGVRQHGFRDGWYVDGASIFLVVFVVATTSAVSRHGQAKQFDKLDMARGSNDMAATVVRAARRQEVSVSDIVVGDVVLLKAGEVVPADGVFLEGHDLQVDESSMNGEPQPVEIDAEKNPFLASGVKVVDGHGRMLVTAVGTNTAWGGMMSSIITTKEQVKNAEPTPLQQRLQGLTSAMGKIGIGVAVLVFTVLAARQHAGTARDSQGKPLFVVAIPEGIPLAVTLALAFTVKRVAKEHALVRRLSACETMGSVTAICTDMTGTLTLNHMVVSEFWVGNDQPKAATALAGSVLSLLRQGAGLNTTGHVYNKPEDNVSSRPQISGSPTEKALLSWAVDYLGTDTDALKKSCEVVRIEAGENRIGVMIRDNAGAVIAHWKGAARMVLPGCSMYVDTRGAAHELGIEQRAKLEKAIDDMAVAGLQCVALAYKQVNRHGKQPTMDDDKGLTLLALVGLKDPCRSDAKSAIDTCAEAGVEVKMVTNANIALARAVAVECGLISDNSPSGITIEGPEFRAMPQEQQLAIVDDIRVMARSLPMDKLLLVQWLKQKGHVVAVTGCGSKDAPALMEADIGLSMGIRGTEIAKESSDIVILNDSFSTVATAVRWGRCVHDNIQKFIQFHVTVNVAALVINYLSAITTGKMPLTTVQLLWINVIMDTMGVLALATGTPTEALMRRPPTGRAAPLISNAMWRNLIAQAAFQVFNLFNAREIEKKKVFAALFNSRMFLTIIAATVVLQAVMVEVLTRFAGTKRLGLGQWGVCFAIAAMSWPIDWAIKFIPVPDWPVIKMKASR
The following text describes a protein:
Function:
Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
MEFSRFSTHLHWLLLFLASRGWVSDAQTCNTSAFADSYRQLFETLGLGKNDTQTTYMRPLSPGKTYTPVFVDLYVNSIIEVFEKEQSLSTQVKMITLWESVKWNQNQFCQIQTIAAAKNSFWAPDLVIAESISTEFGGKESLNVQLIYFGYTLLSEILSLNTACKLDLYKFPFDTQSCNITLQSAAYSNIDLKIFMLHDTGVLTNSSKQSFQSQGEWELLNISTIKSKFSPWYSYTDQLIYQITIRRRPLLHVINIMLPVFSFLVLDVTSFFMDVDGADKLSFKVTLLLAISVLLLILNDTLPSTADKVPLIGIYCSVIFSFIGISILETIFVNFLKARGADSRSSASADVAEQDDGVSGPQVNQDRNQNRQCQTSLCWMRLARITDMLFFILYISSIAVFLTMIGRVWYVL
The following text describes a protein:
Function:
Potential calcium sensor.
Sequence:
MGGAVTKSETLQKEWVPETKLEAKIIEAVQRRASRGTTMKSFNSIVLKFPKIDDGLRNCKAIFQEFDEDSNGSIDHTELKNCIRKLEISFDEEEINDLFKACDINEDMGITFTEFIVLLCLVYLLKDDSSTLQKKWTMGMPKLEPTFETLVDTFVFLDENKDGYVSREEMVRAIDESGERSSGRIAMKRFEEMDWDKNGMVNFKEFLFAFTQWVGIDENEEEEEEDNNEKA
The following text describes a protein:
Function:
An endonuclease that acts in the processing of the 5'-end of 16S rRNA and 23S rRNA. It prefers 5'-monophosphorylated substrates and cleaves single-stranded sites rich in A and U residues; contributes to tRNA processing and mRNA turnover.
Subcellular Localization:
Cytoplasm.
Sequence:
MDAVELLMNVTPNETRIALVETGMLREVHIERQAKRGIVGNIYKGRVTRVLPGMQSAFVDIGLEKAAFLHAADIVSHTECVDENEQKQFKVKSISELVREGQDIVVQVVKEPLGTKGARLTTDITLPSRHLVFMPENSHVGVSQRIESEEERARLKALVEPFCDELGGFIIRTATEGASEEELRQDAEFLKRLWRKVLERKSKYPTKSKIYGEPALPQRILRDFIGTNLEKIRIDSKLCFGEVKEFTDEFMPELSDKLVLYSGNQPIFDVYGVENAIQTALDKRVNLKSGGYLIIEQTEAMTTIDINTGAFVGHRNLEETIFNTNIEATKAIAHELQLRNLGGIIIIDFIDMQTDEHRNRVLQSLCDALSKDRMKTNVNGFTQLGLVEMTRKRTRESLEHVLCDECPTCHGRGRVKTVETVCYEIMREIIRVYHLFSSEQFVVYASPAVSEYLINEESHGLLPEVEMFIGKRVKVKTEQFYNQEQFDVVVM
The following text describes a protein:
Function:
GTPase activating protein of RHO3 and RHO4. Acts in concert with MID2 in cell integrity, which is functionally linked to the PKC pathway. Involved in various stress responses. Required at low pH for activation of the PKC pathway. Important during mating response.
Miscellaneous:
MISCELLANEOUS: Present with 1500 molecules/cell in log phase SD medium; MISCELLANEOUS: Lack of RGD1 diminishes the PKC pathway activity.
Subcellular Localization:
Cytoplasm. Note=Bud and bud neck. During isotropic bud growth in the G1 and S phases, detected at the bud tip. During cytokinesis, undetectable at the bud tip and localized at the bud neck only.
Sequence:
MEETAKKPASATVSAKSSHDGGTDDLAHLFSTPEIKKVLNSDVAINALLSRLKQSLLTCEEFMKFIRKKYAFEEEHVQELSKQYKHFFNIQGSTNSSLKKMIHEVLGFDGKMAQVKQSYITALQKMYSEISSLLLTMTKLRKSVKENSKRLEKDVSDAIHSAEKAQSRYNSLCQDWDKLRMTDPTKTKLTLRGSKTTKEQEEELLRKIDNADLEYKQKVDHSNSLRNTFITKERPRIVQELKDLILEIDTAMTIQLQKYTIWTENLVLNTGVTISPLDSTKSMKSFAGSVSNERDLYSFLNKYNQTGKHSLLINKNLIPVSYKKHPSMNHGQKNKSPPKFAVDPSRNSIPKRMISTHNESPFLSSSSNTAAVPNANLNSATPSLNTNKQLPPTMASSISSTSNAAGAMSPSSSIVTSDTTSSITKTLDPGNNSPQIPEELINSLDSDRPISHIQTNNNMPPGVQKNFKTFGVPLESLIEFEQDMVPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPTTRKNFMHGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAPANPDDANDVNFQIMAMEVLLEVSDQAFEPE
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of N-acylneuraminate 9-phosphate (Neu5Ac-9-P) to sialic acid N-acetylneuraminic acid (Neu5Ac). May also use N-glycoloylneuraminate 9-phosphate as substrate.
Sequence:
MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYSTCITDVRTSHWEEAIQETKGGADNRKLAEECYFLWKSTRLQHMILADDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAIVIGGEQKEEKPAPSIFYHCCDLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKSGRVPLTSSPMPHYMVSSVLELPALLQSIDCKVSMSV
The following text describes a protein:
Function:
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Sequence:
MNLLIKGGRVIDPSQGIDEVLDILVENGAIKELGKGLAAPAGAGVVDAAGLIVTPGLIDMHVHLRDPGLEYKEDIVTGTRAAAAGGFTSVACMPNTKPVNDNKAVTSYIVAKAKAEGLVNVFPVGSITQGSKGDALAEMGDLKEAGCVAVSDDGRPVTSSELMRRALEYAKGMGIMVISHAEDLSLVGEGVMNEGFVSTELGLKGIPWAAEDAATARDVYLAEFTNSPLHIAHVSTMGSLRIIRNAKARGVKVTCETAPHYFSLTDDAVRGYNTNAKMNPPLRTADDLAAVKEALKDGTIDAIATDHAPHHLDEKDVEFNVALNGIIGLETSLPLSLKLVEEGVLTLPALVEKMACNPAAILGIDRGTLRQGAVADITVIDPAAVWTVEAGALASKSKNSPFLGWEMKGAAAYTIVGGTVVHSRG
The following text describes a protein:
Function:
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
Sequence:
MPSITGKTKLLGVIGYPVGHSLSPVMHNAALQAMASDYAYVAFPIAPEDLTIAIAGLGASGVQGLSVTIPHKQVVMPLLTQITETARQVGAVNTLWRDGHGWQGTNTDVEGFLAPLLELKQDWSGRTAVILGYGGAARAVVVGLTQLGCPEIIVVGRSQEKLAQFANSWTDPKIKQALQVLPWEALSTVIPKASLLINSTPVGMAPHPKQSPLDQSLVEKLPPTAIAYDLIYTPRPTRFLQHAQERGLVTIDGAEMLVQQGAAALKIWLQQEVPVDVMRQALLHHLEKSA
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) response.
Subcellular Localization:
Nucleus.
Sequence:
MVEVEEIELDLGLSIGGAFKKSKPESRPDKLISLGHDVGLEQNQQPQMKREIQALRRMEVKRKRVQKRETCLETGDLKPECEQVFKREKTDIVDGVVSWMTPLQVVQRPQQYETLRYRLSLPFSFGSEKNEGRINGVGFNGGDGKVKSNGSSRCSSAISDYQSSSPEDGGSTESRSRSHSANSFAEPTHLKETIQTQPNGIKLNEQSAAAATKTDQIPIPIKKSLPQMPYVSTKGNGSNGKVVNGFLYRYSKCDEVSIVCVCHGSTFSPAEFVQHAGGTDITHPLRHITVNSSAFS
The following text describes a protein:
Function:
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). Has both an aminoacyl-tRNA synthetase activity and is involved in the splicing of group I introns. It acts in intron splicing by stabilizing the catalytically active structure of the intron.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLLRTKALIRSGGSIAKYAAANPSCFILQRRGLRREFGPKYTAKINEAEENWQARAEAIKKGKKQNTWDLFEERGYVKDTAGTKEHIAELMRTRRIGAYVGIDPTAPSLHVGHLLPLMPLFWMYLEGYKAFTLIGGSTAKIGDPTGRLKSRDHLSSSDATMNMTKIHYQLKKLWENVDTQMRARGYEADWARKRGIVNNNHWWNKQPMLEVLRRVGHALRIGPMLSRDTVKNKMTQGDGVSFAEFTYPIMQGWDWFELFYQQGVQMQIGGSDQYGNIISGLEVVKAARESEPDPQERKYVTPKTALDECVGFTVPLLTDSSGAKFGKSAGNAIWLDPYQTSVFDFYGYFVRRSDQEVENLLKLFTFMPISEITKTMEEHIKDPSKRVAQHTLAREVVTLVHGKQEASAAEDQHRMMYTGQMTIPQVSRAKDAATGGDQYKTISDQPVTLNNAPRIDMILPESLIMGKSIGRILYAAGLASSTTEGHKLAAAQGCYVGGAHRAGGENVTMNPDLISFMPVKLWFPGETQRYLINGNLLILRKGKHNVRVIQMVSDVEYAASGQTYPGQSFTGAVRKLNEIMKNLKEKKLTPEEAKNAVNELQKSSQEKQQGQQIIFPEEKSRQKKDMETKLKQEMIASVKTIDGMMDEKPSVRGDGVKKQTQDDRDPYKW
The following text describes a protein:
Function:
Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture (By similarity). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size. Seems to have lineage-specific role in T-cell development (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MEDVEVRFAHLLQPIRDLTKNWEVDVAAQLGEYLEELDQICISFDEGKTTMNFIEAALLIQGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSLVQEDGSKKTVNSETPCETENEFLSLDDFPDSRANVDLKNDQASSELLIIPLLPMALVAPDEVEKNSSPLYSCQGDILASRKDFRMNTCMPNPRGCFMLDPVGMCPVEPVVPVEPYPMSRSQKDPEDAEEQPMEVSRNGSPVPVPDISQEPDGPALSGGEEDAEDGAEPLEVALEPAEPRTSQQSAILPRRYMLRERQGAPEPASRLQETPDPWQSLDPFDSLESKVFQKGKPYSVPPGVEEAPGQKRKRKGATKLQDFHKWYLDAYAEHPDGRRARRKGPTFADMEVLYWKHVKEQLETLQKLRRRKINERWLPGAKQDLWPTEEDRLEESLEDLGVADDFLEPEEYVEEPAGVMPEEAADLDAEAMPESLRYEELVRRNVELFIATSQKFIQETELSQRIRDWEDTIQPLLQEQEQHVPFDIHIYGDQLASRFPQLNEWCPFSELVAGQPAFEVCRSMLASLQLANDYTVEITQQPGLEAAVDTMSLRLLTHQRAHTRFQTYAAPSMAQP
The following text describes a protein:
Function:
No glycosyltransferase or deubiquitinase activity is detected for this potential multifunctional enzyme.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein.
Sequence:
MHKGWKKYFGQKSLNEVTMDDYLASLGLYRKLTAKDASCLFRAVSEQLFFCQIHHPEIRKICVSYMRQNQELFESYVEGPFEKYLERLEDPKESAGQLEITALSLIFNQDFILYKSPGKQPTYATDNNWEGKIMLCCSSNGHYDSVFTKAFQANAAICQAVLYECLYRDVFGVDERELLAAVDLFRSGTKKNRNSASTGSEDANFDCSPEQTSKQSSDNRVKDWEVKGGDNFLDDKSRQTTDDVKSTENPNKMPFPYKVLKALDPEIYRNVEFDVWLDSRKELQKTDYMVFAGRHYCLGDKCQVRLEPGGRYYNAHIQEVGQDSNAVTVFIEELAEKHLVPLINLKPVTQVIPLPAWNSSTNRKGGNYQKMTVGYNGELDLDLKSRKRLFKKVRGKETQGNMPSYDHFRPPQSPHRQGRSYGIPKGSPRYMNRHAIIGPEITFYHSPGKRCYQSLDSYSYRTRSYSRSRRQMACINKECQYGYVPDRDEEPRGMDETMAYYEIEEGDETAYPSLPNQGSTLVPATGFWVARTSPGPISPGKQNLNSSEEEIDEPSDSGEYHEEFIYTSDPAFENSSLYSATESTQNLSLQDDGSHVVPCQDDIASYKFSEQVTSVIATSSCVNAAPVTVMATSAVVIPSTSTSSVLPQTPVQPIIVSSPPSGRPAPTCPGEMGDCTVPLPPPPPPYSCDPSGSDLPRDTKVLQYYFNLGLQCYHQSFWHSMVYVQQIPPPAPVETFQGFPETVPVVDQSAPPVYNESRPIAVETGGPFTNVDPLPSLHGTVYYPLVTDPYNQPPLPGFDSCVPIVPTYHYVGPWHPISPTYSGSPRLHNAVNAGHIHQVSYITPTSPAHFVPQTI
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.
Sequence:
SEMAAAAAPPAAAAAPEPFPDPMPDPFPIHLSSRVNLDHLFAFETVKSLGEPMTPFRLSVYLLIRSLDADIYEEGCSGENHARISALLYGLLEAQQELTFAQVCRLVRKRVCPIIHDALDHYLKMVQEALQTDGITLKFDSLGLKRGLVANKSLLEHYVQRLQSAEKLMTYQQHRQLMQQLKAFVKGEENKDVLMRAIAAPAPSLPRCISTGSHARVWLMQQLHLQQVSPLEVDVRIDEYAGLVAAAFRDIPAVHLLLMLRAVYRVDQPTAVDELRAFFDYSMIRLQDLLTHIAPQKNRMVTVDHRQVRYAPLLQARLYRIFGDKALARRLLNETISQAYLNKEMTCLRLALVESAAVEIMPERREHAMKTRKPANDGRQKEAKKEQRDTLHAEDESELVPASIKSVDLKSHLAMMADDVPARMEGEERRELSTDPQEHQYMVMRSVDTGKLVAAITMFIKCDIPEAREDVPMAPLQHAVIGASCSSSGPDSMGKSRELSDAAAAFTAVARLHAGYVVSATAHARALYECDMPDYYAKRHDTETKAVAGVTMAFGLASNGEWTEALSLCAQLEARFCVKGSYPAATRHVVGAAALIRFDAAFVKGNFAAAEDCLLTVESVHPNEAAMRRCLLLCARGNQSDAVALLKLAREGVNEDLDLPTAIRMDMQLGVLLARVGEGQPALQLLQKTVRLSSSRGLQRLHVMSQRRLAMVELMFGCAKDAKRILETIEAEIHSTGGLIERVLYCLTVAECGYQIKQCAIRDKKEWAAGASGHVSALGRARLHAEQIGCTPLEKTALSMAARVMNKGEHFSKIVERLKELNDKCPANIDWTTM
The following text describes a protein:
Function:
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Subcellular Localization:
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus.
Sequence:
MGTLLLNLGQCGNQLALQMFNLIDKSSMHEGNMFLRRRESNIYHTILVDTEPKILKPIVEDRKLYSHIDVKNVLYYQYGRGNNWGLGYLNFKQKSKLSKSNQQQAISVFKSSTNEVSIQQYCQENEQIVEQIINQARKEIEKTDYFLSISTIMSLAGGTGSGLGSRVIQEFSDIFQEVHQNVIAIFPNKTGETPLQHYNTLLSSAHIQQYADSIIYFENDRIYQMLSQIGSKQIDKSVDLSNVNEYIGSCLMNLFWINDNSTNVRYYQDLLSECCITEGHKFIEVVSAPFTLFSHSNLGPLCTWEDLIKSSLEQYAFEKFEDDSDQQQQIGEAVAKSLQIQSVQKKGETTLNLQSVFRSENVLKTLQDSDSHMKFLERKINSVFNPVQWNPDAVQLHFINEKSSVKGHDQKMNVTLINSTKIIPILKNVSKIAYQKYRSGAYLHWYWKYGLENQDFDNAFESLQKIQDDYNYMVEY