lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Forms a complex with CCMFN1, CCMFN2 and CCMH that performs the assembly of heme with c-type apocytochromes in mitochondria.
Miscellaneous:
MISCELLANEOUS: A stretch of 270 kb of the mitochondrial genome is duplicated within the centromere of chromosome 2 resulting in the duplication of the gene. The expression of the duplicated gene (At2g07723) is not demonstrated. It is also probably not RNA edited and therefore differs in all the positions known to be edited.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MVQLHNFFFFIIFMVVLCGTAAPVLLKWFVSRDVSTGAPFFNGTIIPILISLFSLLVYLHSRKIIRSMDGAKSGVLVRASRPILLPDIIGRSSSETRARKALFFFVPVLHFCLLESKGDFSYLESFCGVLCLLFFCTFFFLARDRSAKRERARRRKGQTLRPNGNEQRRNDKMRCSGHPHLDLERRVEGFGPLAFPVPPELGGACVGGVPPEIGLEALALPRSRQLMAMAVGHDYYQKVPMKMNISHGGVCICMLGVLLSNTKKIQFTQRLPLGYELHMGKERCCLRGLDHLHGPTFHSICGNLMIYKPSLTNDRLMFEHDESLHADLLLINFPASYKNGKLEHFLHWWMKNRKHNNFWLTMFPEKRYFRERTSTAEVAIHTNLFTDLYALIGTGSSRTGGWYTTIMKLPFIFFIWIGFMLASLGGLPSLLRQLQKDKLRWN
The following text describes a protein:
Function:
Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.
Sequence:
MRRSLRARSGRFTLGLTKCEACFRQRTNASLKGAGQTGNAVVWSALQGRVSNRLARHFRAAPHRLPAHAPMVSFTFDDAPDSAAGEGASLLEAHGGRGTYYIAGSLIGRPSDHWHGLSNDAIVRLHHAGHEIACHTFSHQSAVNLGEAAMTREIERNRSHLREIDSSIALENFAYPYGLASVWRKPQLARTFRSARGILPGVNRDVIDLQFLRASPLVDCEIDRAGVDRYFDEAVASGGWLIFYGHDVVNAPSPYGCTPHLMRHALEAAGKRDMPIVTVAEALRRIGA
The following text describes a protein:
Function:
Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis, programmed cell death, biofilm formation and cell wall metabolism. Also participates in sensing and responding to host defense cationic antimicrobial peptides (HDPs). Upon phosphorylation by LytS, functions as a transcription regulator by direct binding to promoter regions of target genes including lrgA and lrgB, to positively regulate their expression.
Subcellular Localization:
Cytoplasm.
Sequence:
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNNASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPTYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
The following text describes a protein:
Function:
May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells.
Subcellular Localization:
Cell projection, cilium.
Sequence:
MSHLVDPTSGDLPVRDIDAIPLVLPASKGKNMKTQPPLSRMNREELEDSFFRLREDHMLVKELSWKQQDEIKRLRTTLLRLTAAGRDLRVAEEAAPLSETARRGQKAGWRQRLSMHQRPQMHRLQGHFHRVGPASPRRAQPRVQVGHRQLHTAGAPVPEKPKRGPRDRLSYTAPPSFKEHATNENRGEVAPEPSELVSGSNSIISFSSVISMAKPIGLCMPNSAHIMASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEVSCTFLLPQNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIVEQLQQQVSQLQDQLDAELEDKRKVLLELSWEKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKDVAYGTRPLSLCLETLPAHGDEDKVDISLLHQGENLFELHIHQAFLTSAALAQAGDTQPTTFCTYSFYDFETHCTPLSVGPQPLYDFTSQYVMETDSLFLHYLQEASARLDVYQAVASEHSTLAAGWICFDRVLETVEKVHGLATLIGAGGEEFGVLEYWMRLRFPIKPSLQACSKRKKAQVYLSTDVLGGRKAQEEEFRSESWEPQNELWIEITKCCGLRSRWLGTQPSPYAVYRFFTFSDHDTAIIPASNNPYFRDQARFPVLVTSDLDQYLRREALSIHVFDDEDLEPGSYLGRARVPLLPLAKNESIKGDFNLTDPAEKPNGSIQVQLDWKFPYIPPESFLKPEAQTKGKDTKDSSNISSEEEKASFPSQDQMASPGVPIEAGQYRAKIKPPHGGERKEKEHQVVSYSRRKHGKRIGVQGKNRMEYLSLNILNGNTPEQVNYTEWKFSETNSFIGDGFKNQHKEEEMTLSHSALKQKEPLHPVNDKESSEQGSEVSEAQTTDSDDVIVPPMSQKYPKADSEKMCIEIVSLAFYPEAEVMSDENIKQVYVEYKFYDLPLSETETPVSLRKPRAGEEIHFHFSKVIDLNPQEQQGRRQFLFDMLNGQDPDQGHLKFTVVSDPLDEEKKECEEVGYAYLQLWQILESGRDILEQELDIVSPEDLATPIGRLKVSLQAAAVLHAIYKEMTEDLFS
The following text describes a protein:
Function:
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
Miscellaneous:
MISCELLANEOUS: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MAKPLSISSQPSVNVAWRDYFEMTKPKVVALMLLTVLVGMCLAMPTILPVQPLIAGLLGIAMMAGSAAALNHLIDRRIDGLMARTYNRPLPKGRISATRALIFAAALGSLGFVILYVFTNPLTAWLTFASLIGYALIYTAYLKRATPQNIVIGGLAGAMPPLLGWTAVTNQFHGHALLLVIIIFLWTPPHFWALAIHRRAEYAKVDIPMLPVTHGVEFTKTCILLYTILLAIACLLPVLVGMSGPLYFVCSSALSCGFIYKAWQLKYQDHEGLAMQVFRFSIYHLMLLFMALLLDHYLWA
The following text describes a protein:
Function:
Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MLGRPAGHSAMGSPRVALLMLLLRPIKLLRRRFRLLLLLAVVSVGLWTLYLELVASAQVGGNPLNHRYSSWRELAKALASRNIPAVDPNLQFYRPQQPSLKDQGIARSRSRNSSYLKWNKPVPWLSEFQGHANLHVFEDWCGSSIQQLRSNLHFPLYPHIRTTLRKLAVSPKWTNYGLRIFGYLHPFTDGKIQFAIAADDNAEFWLSRDDQVSGLQLLASVGKTGKEWTAPGEFGKFQSQISKPVSLSASLRYYFEVLHKQNDEGTDHVEVAWRRNDPGAMFTIIDSPYLSLFTNETILRMDEVGHIPQTAASHVGSPNSPPQDEQPPADMLRPDPRDTLYRVPLIPKSHLRHVLPDCPYKPSYLVDGLPLQRYQGLRFVHLSFVYPNDYTRLSHMETHNKCFYQESAYDQDRSGFQEYIKMDTPGKQGPEQPAGLEDGLLEESQYEEAPGEIPTSRDRNAGTQGRKQKTTSAPGLGVTDYHLRKLLARTQNGPLAPLSKQNSTATFPSRTKDNPVRQPEKRTGKTSPMPSRDLGDKVARRNLPVIQRARPTGDGPGKTLEQSQWLNQVESFIAEQRRGDRMEPPTPSRGWHAQEDVVIAADQEGEVEEEEEGEDEEEDMNEVFEYVPVFDPVVNWGQTFSAQNLDFQALRTDWIDLNCNTSGNLLLPEQEALEVTRVFLRKLSQRTRGRYQLQRIVNVEKRQDRLRGGRYLLELELLEGQRLVRLSEYVSTRGWRGGDPAGREDTEARNLQGLVWSPRSHHRQVSNAQDPEPKLCWPQGFSWNHRAVVHFIVPVKNQARWVQQFIRDMESLSQVTGDSRFSVIVTDYSSEDMNVEMALKRSRLRSYQYLKLNGNFERSAGLQAGIDLVKDPHSIIFLCDLHIHFPAGIIDTIRKHCVEGKMAFAPMVMRLHCGATPQWPEGYWEVNGFGLLGIYKSDLDKIGGMNTKEFRDRWGGEDWELLDRILQAGLEVERLSLRNFFHHFHSKRGMWNRRQMKMP
The following text describes a protein:
Function:
Involved in the control of root gravitropism.
Sequence:
MKFFNWMQNKLGGKQENRKSNTSTSTTYAKPEPREEFSDWPHSLLAIGTFGNNNEITQNIENQNTQQEDPSSSEEVPDFTPEEIGKLQKELTRLLRRKPNVEKEISELPLDRFLNCPSSLEVDRRISNALCSESGGDKDEDIEKTLSVILDKCKDICAEKSKKSIGKKSISFLLKKMFVCRSGFAPTPSLRDTLQESRMEKLLRTMLHKKLYTQNNSRAPVLKKCLENKKSIKKRNEDEAEERIDEGSKWVKTDSEYIVLEI
The following text describes a protein:
Function:
This protein is a negative regulator of both sexual conjugation and meiosis. It phosphorylates mei2. It blocks the onset of meiosis until conjugation takes place.
Sequence:
MMRENPELLLGQVLGDSLRFVSIIGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQARELALHARVSSHPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQLISAVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGLATTEPYSSDFGCGSLFYMSPECQREVKKLSSLSDMLPVTPEPIESQSSSFATAPNDVWALGIILINLCCKRNPWKRACSQTDGTYRSYVHNPSTLLSILPISRELNSLLNRIFDRNPKTRITLPELSTLVSNCKNLTRRLRPAPLVSSRYLAYQQQQQQQQMNLQQGIQGYPHQGYMPTQNIGFPWPPTPQFVSNWNHCATPTIPVSLQVLTPNSSLKVDPTTPLTAPIHATESFWPSAAAAAAAVHNNANSYMPITPTPYPNNAKIFGYPNQPPLTPIPFTGFVLHPAPVGRAADAVDPSRKSL
The following text describes a protein:
Function:
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Sequence:
MESKQDSNSSSYSTKIFGVLNITEDSFSDGGKYLTFKSSSEKANSLLNQGADVIDIGAQSSNIQASLIGPEIEWIRMKELISNLVAKGVRISVDSFQPQVIANSLSAGVEFINHIRGFVDEESIREISKYARTNRKFILMYSHNHSNRAETKSHLTPNNVILEIVRFFRERKKILLNAGIAQEQLIFDPGMGFFLSSDFQVSFEVLKKIKTLQEEFSPMMVSVTKKSFLGNALGGLKVEEREIPTVIAELYLCIQNVEYIRTHEPKNLKQALKIWNLMNK
The following text describes a protein:
Function:
Catalyzes the conversion of uridine into UMP and cytidine into CMP in the pyrimidine salvage pathway.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSHRIAPSKERSSSFISILDDETRDTLKANAVMDGEVDVKKTKGKSSRYIPPWTTPYIIGIGGASGSGKTSVAAKIVSSINVPWTVLISLDNFYNPLGPEDRARAFKNEYDFDEPNAINLDLAYKCILNLKEGKRTNIPVYSFVHHNRVPDKNIVIYGASVVVIEGIYALYDRRLLDLMDLKIYVDADLDVCLARRLSRDIVSRGRDLDGCIQQWEKFVKPNAVKFVKPTMKNADAIIPSMSDNATAVNLIINHIKSKLELKSNEHLRELIKLGSSPSQDVLNRNIIHELPPTNQVLSLHTMLLNKNLNCADFVFYFDRLATILLSWALDDIPVAHTNIITPGEHTMENVIACQFDQVTAVNIIRSGDCFMKSLRKTIPNITIGKLLIQSDSQTGEPQLHCEFLPPNIEKFGKVFLMEGQIISGAAMIMAIQVLLDHGIDLEKISVVVYLATEVGIRRILNAFDNKVNIFAGMIISREKLQNHQYKWALTRFFDSKYFGCD
The following text describes a protein:
Function:
Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen (Probable). Associates with FREE1 and ELC to perform function in the ESCRT-I complex. Binds ubiquitin in vitro. Plays a role in the biogenesis of vacuole and multivesicular bodies (MVBs). Required for the endosomal location of AMSH3. Mediates high-affinity phosphate transporter trafficking to maintain phosphate homeostasis. Regulates vacuolar degradation of PHT1-1.
Subcellular Localization:
Cytoplasm. Late endosome. Endosome, multivesicular body.
Sequence:
MASSSLSNLMLAIHEKKTSSVDLYRPLRNYVTFTYSEREAQLIDDDLETLKQLRSDIERVSDPSPAARRDLLISYYKVLCLVETRFPISPDKDHVNAVSFVWYDAFKQKHKATQQNIHLEKAAVLFNLGASYSQIGLGHDRTTVDGRRQASHAFMAAAGAFAHLRDNESIKATIGPSTTVDVSVECVGMLERLMVAQAQECVFENTIAKGSTPGVSAKIARQVGIFYEEALSALIISPLKDHFDKGWISHVQLKAALFYGEACFRYGKELHEKEEIAEEIARLRSGASRLAEAKKSSRGAPAQLIEAMNTLESSINGNLDRAVKENDRVYLMRVPSPSSLSPLPAFSMVKPMNMTDILDASKEKMFSILVPDSSAKALSRYTEMVDDVIRTQAERLQQASELTRVRLKEMDLPDSILAVDGNSALPVDLKEDVEAVQISGGPAGLEAELQQLRDLKRVNQELLVHTEELLQKEATEDSQFRSQFGTRWTRPQSSTLTKNLQDRLNRFAANLKQAGESDVKIERSVRDNSALMSILDRRPIESAVPTLARPIMSLDATEDAIVGTLKQSLRQLENLGAQRAGLEDMLKEMKRKDDILPKLMTITGSYEDMFRKEISKYDHICEDISQNIEVQEQLLMQIQAQNEEFSTIFNLEDYKASKEKCYKQIQAAIMKYREIKENINEGLKFYVTLQDAITNVKQQCSDFVMTRSIQCRDMIEDVQRQMSGLSFQDHRSSGPYPSVHQPTASSPPPPPETQNPSHPHPHAPYYRPPEQMSRPGYSIPPYGPPPPYHTPHGQAPQPYPPQAQQQPHPSWQQGSYYDPQGQQPRPPYPGQSPYQPPHQGGGYYRQ
The following text describes a protein:
Function:
Putative odorant or sperm cell receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MIGVWSMSLCLPRLKKSQISGDLNCLPKMLASWSFANIFFFQPPAFLMIGIPGLETVHGWISILFSSMYTVALTGNCLILLAVRRTPSLHQPMYYFLSMLALTDMGLTLATMPTMLAVLWFDHRLIGFNACLIQLLFLHSLSMVESSVLLAMSFDRFVAISNPLRYASVLTNNVIIRIGLAIMAHATVSLFPGPFLLKRLNFCPGKILLSHSFCFHADVMKRACADITVNIIYGLYVVLSTVGFDSLLIVLSYTFIFHFHALEKEMQPTPVFLPGESQGQRRLEGCRL
The following text describes a protein:
Function:
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Sequence:
MGHQQLYRSHPRKFGQGSRSCHVCSNLHSLIRKYGLNMCRQYFCQYAKDIGFIELD
The following text describes a protein:
Function:
Enables the bacterium to metabolize sucrose as a sole carbon source.
Subcellular Localization:
Cytoplasm.
Sequence:
MTEWTREERYQRIEDVDTEYFKTLKQQVDQSKFRQQFHIQPETGLLNDPNGLIFYKGKYYVSHQWFPLGAVHGLKYWYNYTSDDLINFKAEGPILNPDTKYDSHGVYSGSAFEYNGHLYYMYTGNHRDNHWQRHASQMIARLKEDGSVEKFPKPVISQQPEGYTSHFRDPKVFKYDEKYYAIIGAQNNDQQGRLLLYNTEDIINWHYLGEINTELDDFGYMWECPDYFNVDNQDVILICPQGIEPKGDQFKNIYQSGYILGKFDIEKLTYEHENFVELDNGFDFYAPQTFLDEKGRRVLIGWMGLPEIEYPTDNEGWAHCLTIPRVLNVENGQLKQRPYPALEKLRHNKETALGYANKFTRKLHPYEGKQYELIIDILDNDATEVYFELRTSKTSSTLIAYNKRENKITLDRSDSGLLPTNVEGTTRSTILDTPLKQLQIFVDTSSIEIFCNDGERVLTSRIFPTEDALGIKTSTESGQVYLQFTKYDLKDEHK
The following text describes a protein:
Function:
Acts as a transcriptional regulator (By similarity). Regulates expression of various genes, including homeobox protein unc-42 and helix-loop-helix protein hlh-34. Required for embryonic viability, neuromuscular development, organization of the nerve ring and neuronal cell body location. Regulates AIY neuron axon morphology and cell fate. Plays a role in cell autonomously establishing a neuronal left-right asymmetry. Involved in regulating glial specification.
Subcellular Localization:
Nucleus.
Sequence:
MYHHSPFYPHHLQTGEQDLDMERENDMDQNSKNSTQKPVKREKRRYRCRKRSPATIERAKTVRRDKANARERRRMNSLNDALEHLRGILPALPDEPKMTKIETLRKAQEYIASLSFQLSGGSPDSSQCCETGSCGLCSASQSLQSTPFQSPCFPQPLQYPSSYSNPPSQMYYHHHHQSPSFPHH
The following text describes a protein:
Function:
Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity).
Subcellular Localization:
Nucleus. Chromosome, telomere. Note=Localizes to nuclear DNA repair foci with other DNA repair proteins in response to DNA double strand breaks.
Sequence:
MVIRGVCDSISRDIASSAVTGKRHTTQMSIFKTIARGHGRFKARSSRQFIVSTVCELLLARHKDRGSQLIVASNLRLVLSHKPHLEHLLWDHYRRSVACLCRELSALCVNSMEESGLEMLIQELLLCLDLLTKPKYVGMAELKHDLWNCIDSMLYKYKEVSEMHVLILSISVSLFQVVFGSDYEICHEMVPSIFAIGTKLFTSKSKAVREISLRFLLKMEIYLASIFGKTCPVPLDQDRLNQIEDHMVELLQVLKNEYNSSSLQDNDVVFEDEIVLVNSKKTMQFLICKLIAMLEYVLSYTLTDGNVKQEEDLHGPRKKPRVSISPETPTLNAISAQIQAFQASKPISEVDKPLASLLSSISGSLDKTTRWKFFSAAKLLAQSPPLSPKNAHDVVFLTKWWTEGVAKLRTRSEDSACVLLTTILRQHSSALDPKLVVSLASNAESKGPLKYSNVSLEFVTCASQFLISHKACSQSQWSDWLFVVLASEQIGATSSKMMLDTAGLLLASVGCLIRMIETPQNTLETTTSSIMWKTDFKTTSSTSGDIELTECMPSITIRDLKSGFQNYLNELGDWCESASIDVNVVLPSTVFALVVCAVLDRQGTPVGLNSRISDFLAVVTKRVEGGSCDSHVFFEAITLINRLRHYNLLGDSLCILWDSFINGIEKLLNVSQVTENEFDPDSPSGKNIMPDLRLSLLLRGPLKSEPFLLAIFPSDIKQYASCDPGKRLPELFRYVGQTLLSSYLWDCSPLAKQLVVDLLDVYFKSGMTESSDADDLQRWVSRDKFLVGPQLLYGLMQVSTPSEYLNLYSSVAICAAERVSSQDSYHCMDATLTRMSSAKSKSRLVVEEMIVALLSVHRECLSLLPVVIERVKTDMLRQKLDTDSESLVRFCKQTGTDSILDKILSVKVGSCVFEEEGHFSTQQLLCSEDSLQWNTQGPPLDILSRTWPDYSPCTLLMLVRGLLNLMLKPRVSFEVPLRLVQLKYVLCLFPKRDLCSPDNYVLQQMVSCLISFLSHSTVGASVRHLLSELFEVIKLPHLEGYIADLGEQSFFGADVSQLLYLLHPSEPHLCKYIEWVNSGFSDPEAFLSVFLHTEISDKLKATLLKSLDFGVTNMTLLGLMDIVCTKETVSFIKRASKLYSFDWEESRVLSLLLGRGYLLFGESSNSAPKTNTETSFWNALTSEFLTLLRGSDFTAKFAVEVCLSKIVTKVQVQVPAELQHVFDSGVLEYTHTDEPTTGWVQKTTLELLGLLGGDFELLIPLVRTLSSTSPLLPFIFKWTCLEYCRQGEPSYLSQILSQNSSLVVIETFFFVNSFTAHRTLNWQPEIVNSALTLHLYTEALYFLEADKACWASQEIQPSYYDIYQNIDDPDLFYGLKFTPCLESALKQLNHENQNLTCFEYESGLFDWSVETGGGESKTDILSHLSTSGMNGLAYTINSDDVYRWKLGLLEDPILETGTDDQTVLSQLRSIVVDEKPVLKSTLSDKYLGMQYLLYQMQLDANSDYLDRIQPPDGVLDILQFCASAWRTIKTETASYNGILTLSKLGAVSRELNNAQISKNCAVSLQELSRTASHISGNVCAISIASCLWSEAAVSRTTPVEMLKRMLGSINPGQSPVLASQFCQATVLLTDWSSQARMMSPEKIHRLYIAGASEYMALIPAGNPKTRMFHVFAKFCETQLHSQNYDEQIHNAVMDIERLEGELANLSRISMTREIKHAQRISRKSLDRAKESKLNYERLKAMFLDSAVQFYLLSCAVRDSEYHEDVTRLISLWFGNSHVNFVNERMQDYALIPSFKLAPLINQLSSKLSYEPNNYFQTLLLDLVSATCKAHPFHCLYQISSLMRTDASPQTERRIQAAVKVWNTVKTQEKTICRAMEIFTDKCVELANAEWPGKGQKASINQFPNGSWWQNGLRKLNIPPPTAQIPLSLDYTDIPSMNKVLAQVIKAGGISHPKIMDFQLSDGSVSKALLKGGKDDMRQDAIMEQVFCRVNQYFLGDPETRKRGLSIRTYNVVPMGPRAGMIEFVANTESLQAALVPLHEKDDWDYLTGRTKMSAVAKESNSRRVEVLEEIYTHVTPVMSQYFFQNFRSSAQAWFKARTNYVRSAAASSMLGYILGIGDRHCNNIMIDYKTGQLVHIDLGISFDQGKNLTVPEKVPFRLTRDMVDAMGSVGVDGPFRRCCELSLGLFREQQDNILSILNVLRYDPLYSWTMSPKKKQTRSSSGSDLSDIKLEESNVTADMCLSGVKGKLAVRLSTEAVVRELIGEAVSVENLAVIFHGWTPFY
The following text describes a protein:
Function:
DNA-binding protein that plays a critical role in nucleoid compaction, genome replication and DNA replication and transcription. Binds to both ssDNA and dsDNA with a binding site covering about 15 nucleotides. Displays DNA-supercoiling activity only when associated with the viral DNA topoisomerase 2.
Subcellular Localization:
Virion.
Sequence:
MAIQVKASLRKNPQDKKAAGKYYAQVVLAPEMTQRQIIDQIADRCTVTGSDVKAVLDALMTVIKRNLANGSPIRLGDLGSFRPSVSGIGSENVDKFTASNVKKARVIYVPSAEIKEAVAMYAFSKVGATAEGGNTEKPGGGDIDNPGGGDEEAPDPTV
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MGFFGSKKAKAASSPSSQDVSKPTAATDTADDAAEKGYFPPVDHDNKSTSTKSTATSKSTSSIKSSSSVKSKFNGVKGEVQPRKVKDLSFSILFFLHVGAMIFLFATTELPNAGGYGNSYTSLAFFGTYCSVFAAALSAAIFAFMVKKPDNWIKTSISISLNVFLGMGVFGLLVGEMVMSVLSFILFSVFGIYMVSAWKRIPYISSNFSTAIHVIKSNRGMSTAAVILQLVSIGWTIVWLIACTGAIHLVGPGIIVVFAISYFWVQQVLKNMMHVTAAGVVGRWWHTATRDPNFTESEVLNSLRKAYTTSFGSICFGSLVVNYFNGLRKLLSYSNGKSGFGFLYDAVTCLLGCIREFIVYTNKFAFVYIGLYGYSFIQAGQNVTVLLRGKGWKELITDDLSDNLLFIVNCAVSCCTGLMGVLFTGQSSHYRLLYAIGYKHPYTAGFVIGATVGFLVSSVILGVIGGAVNAVIVCFAESSVEFHQNHPRHSQKLRLTKNNFIRLTSAGR
The following text describes a protein:
Function:
Required for nuclear membrane fusion during karyogamy.
Subcellular Localization:
Endoplasmic reticulum membrane. Nucleus membrane.
Sequence:
MNWLQSGRIPFLFMTAGSVWGFRFGFQESKSVASSKESTAHQAVLENELRMPSLMSELEERLQGVSIEPDREESSCYSRIFGALTNPEKSAVPEPSLCSVLGRSEAHRTAFAARLTICELETNRLTLPRECSLWIEAGSEPTSEKLQACVGALHASPQSWSSFTGHQREAVQLCFAHHKLQGIELATSLNLKTIKFSTDMIRLSRLDHQSNQEDLRNLRDHMRDRFDQSLRNLDSVSESNRLESQKLFRELEARFQDVKSHLYERNQQLWNEFHSHQNQQIENIQDRVQSLNNNNQLKLNENVNNFILSMKEEVEQKIQSSLDSAAAGMIANLKQAFELESRSNSANVNHQIKQAFEAALDLATHRHHQGLEESITAQSQRMAALFEELLSVENILSSMKQNLDSMQITSSDRESILRESSAKIEEQQRKGEELIHRFMESMATHQAMIQTLTDTVSDSPLFVFYSFFKTGFLSCKEIAIFRK
The following text describes a protein:
Function:
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues. Together with RNA binding proteins RBPMS and RBFOX2, activates vascular smooth muscle cells alternative splicing events. Regulates NCOR2 alternative splicing (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm. Cytoplasmic granule. Note=Localized with DDX1, TIAL1 and YBX1 in stress granules upon stress. Localized in the cytoplasm of multinucleated myotubes. Colocalizes with nuclear foci of retained expanded-repeat transcripts in myotubes from patients affected by myotonic dystrophy.
Sequence:
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM
The following text describes a protein:
Function:
Catalyzes the NAD(P)H-dependent reduction of mycothione (the oxidized disulfide form of mycothiol) to mycothiol.
Sequence:
METYDIAIIGTGSGNSILDERYASKRAAICEQGTFGGTCLNVGCIPTKMFVYAAEVAKTIRGASRYGIDAHIDRVRWDDVVSRVFGRIDPIALSGEDYRRCAPNIDVYRTHTRFGPVQADGRYLLRTDAGEEFTAEQVVIAAGSRPVIPPAILASGVDYHTSDTVMRIAELPEHIVIVGSGFIAAEFAHVFSALGVRVTLVIRGSCLLRHCDDTICERFTRIASTKWELRTHRNVVDGQQRGSGVALRLDDGCTINADLLLVATGRVSNADLLDAEQAGVDVEDGRVIVDEYQRTSARGVFALGDVSSPYLLKHVANHEARVVQHNLLCDWEDTQSMIVTDHRYVPAAVFTDPQIAAVGLTENQAVAKGLDISVKIQDYGDVAYGWAMEDTSGIVKLITERGSGRLLGAHIMGYQASSLIQPLIQAMSFGLTAAEMARGQYWIHPALPEVVENALLGLR
The following text describes a protein:
Function:
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MIINKFSLKWMLAIAVAIPAIALLFVAFTSLNTMSVMQAQSNSLYANTAAPMRAMAEATSRIPRMRVGIDMMLLQETALKDAKGVLKRVEEARTEDIPEMRQAMQVAVDSQVNPELKEQARKLQARFEQMVREELEPMLQAFANNDMTTAQNIYRDKYAPTYGEMRKQANQILDTLLQQAEQQNHASVESFEAGRTKQMVIIAAGLIISFITSLVIITNLRSRVAYLKDRMSSAAANLSLRTRLELDGNDELCDIGKSFNAFIDKVHHSIEEVAENSKELATMASSVSQRAHMTQSNCASQRDRTVQVATAIHELGATVSEIASNAAMAADVAKQATLHSGEGKKVVGEVQNRIQTLVNELDNATQVVSSLATQINGISSTLDTIRSISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRSAASTEEIQQVINRLQTESTRAVEAMEKGRSQSDVVVEFSAKANQSLTEINSQIDQINDQNIQVATATEEQSTVVEDINRNVEDINQLTTETSHVADELSRASASLQRLSSQLDKLVGSFEL
The following text describes a protein:
Function:
Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. Component of the PcG multiprotein PRC1 complex, a complex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-118', rendering chromatin heritably changed in its expressibility. Promotes locus-specific chromatin compaction. Binds to (N(6)-methyladenosine) DNA and thereby might implement repression of specific loci.
Subcellular Localization:
Nucleus. Chromosome. Note=Recruitment to chromatin is not dependent on a functional PRC2 complex and H3K27me3 histone modification.
Sequence:
MTGRGKGSKGKLGRDNATDDPVDLVYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWEPEVNILDRRLIDIYEQTNKSSGTPSKRGIKKKEKEPDPEPESEEDEYTFTENDVDTHQATTSSATHDKESKKEKKHHHHHHHHHHIKSERNSGRRSESPLTHHHHHHHHESKRQRIDHSSSSNSSFTHNSFVPEPDSNSSSSEDQPLIGTKRKAEVLKESGKIGVTIKTSPDGPTIKPQPTQQVTPSQQQPFQDQQQAEKIASEAATQLKSEQQATPLATEAINTTPAESGAEEEEVANEEGNQQAPQVPSENNNIPKPCNNLAINQKQPLTPLSPRALPPRFWLPAKCNISNRVVITDVTVNLETVTIRECKTERGFFRERDMKGDSSPVA
The following text describes a protein:
Function:
Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MANQSTGLTRIYKAAGYTVKGLTAAWNNEAAFRQESVAAVIAIILAFWLDVGAIARILLICSVVLVLIVEVINSAIEAVVDRIGSEFHALSGRAKDMGSAAVFLTILMALFVWITVLWQHVAR
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MSSPPNPRARKQPRRGRHSSQLASSIGNARGGRKVQNTSPIQNASFSTSASFAEEMSAVSAPPLSTAVPLDTPRFADLGAENLLNPILLKTITEDLKFDHMMPVQAATLRPLLSERVDCLAQAKTGTGKTIAFLIPAIQTLINKQRRPQDGISLLVMTPTRELAQQIAKEASQLLKNLPNYKVGFAIGGTNKTTEEKNILNGCNILIATPGRLFDHLSDEGITNAFRNLDTIVLDEADRLLDMGFMNAIRDIIKCLPDKQKTKRQGMLFSATIAPHVEKVAHLVLSKDYKFISTIPEGEVNTHARVPQHLITVPNFSDVASAMVGSIRAEMKLEGKDSFKAIVFAPTAALVDFYAQILSQFKDLPPVTALHSRVSQGKRTVVTEEYRVAKNGILVATDVIARGMDFPSVTNVFQVGLPADKESYIHRLGRTARAGKEGRGVFILTEVESPFSTWTLKEIEFVKTEADLSSAPQVLKIASRMENHSKTYQAWLGYYKNHLKLMQWDNVELVRQGNIFARDGLGAPETPSLYRGIVGKMGLKGTEGLIVIPDPPRVPRGGGGGGGGGGEGRSVGSGGRGGGGGRSIGSGGRGGGEGRSIGSGGRGGARGGHEERSVGIGGRGGGEGRSAGGGERGGARGGARGGGEGRNAGSGGRGGARGGRGGFNINRSAW
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
Subcellular Localization:
Nucleus.
Sequence:
MGSSVFDDILSSSQCEYGFKIKSDDDGDDTDHGDDADARAKSFFKHIWQHQPMIFRSTHKTCQADGILRQTMTMGFNGVADMLHNCRKSSSPQSDDTSTNSAATAPPLFFQNGSPITDPYSMYSSNPHAAYLDGCSIVVNHADLQSASIAKLCNDLQSSFPHVYANAYLTPPNGFAVNAHADDRDVFVIQVLGTKKWNVYKKVPVEYPFENEQVGKSGREVPPSVFEGGLCFGNNVLDLGPGDVMYMPRGFVHEATTEILDVEDGHSPSFHITIAIATHDWCLSVVLADCFRKTLSEVVDYRKALPIGPSKEYEPEDSSSFLKRQLNQAMKLVQSSVTADMLDQHLRAKYKMHNTLANEYRSRIIISHQSKKRKASEDGVVGYKAASALTLESVIRVSTPEERNSVVMEEGQHRGLTVRDETRDILLQTLGAIKGDPSLRVKVGDLRGLIGDAEIERDNDLSMICDFTQLSFARCCVELGALAVVEEH