lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Non-TIFY functional repressor of jasmonate (JA)-mediated growth and defense responses. Intrinsically resistant to JA-induced turnover, probably due to the absence of the canonical degron that strongly interacts with COI1 in the presence of JA-Ile in the TIFY/JAZ proteins.
Domain:
The jas motif (82-103) lacks the canonical degron LPIARR that strongly interacts with COI1 in the presence of JA-Ile in other TIFY/JAZ proteins. Contains 1 EAR motif required for the interaction with TPL.
Sequence:
MKGCSLDLHLSPMASTLQSCHQDSTVNDRSSTIRSKEINAFYSGRLSEYDLVEIQMRAIIEMASKDREVTALELVPVRLESPLGCSVKRSVKRFLEKRKKRSKSFTLTPNYTSSTSSSSSSLHNF
The following text describes a protein:
Function:
Probably functions as a manganese efflux pump.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDLISVILISIGLSMDAFAVSITNGAMISKVTASEGIRIGLFFGGFQALMPLIGWSIGIKFESYIAALDHWIALILLSIIGGKMIYDSVKENQDHKDEIACDYAAGEKKCLNNKTLILLAIATSIDALAVGVSFAFLKVSIINTIIIIGSITFVICFIGVMIGKKCGKLLKKRAEILGGVVLILIGVKIFIQHTNILSYIF
The following text describes a protein:
Function:
Probable amino acid transporter of unknown specificity.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MPSNVRSGVLTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCGICSLCGLLLQTRIAKYVPKSENASFAKLTQLINPSISVVFDFAIAVKCFGVGVSYLIIVGDLVPQIVQSIFYRNDDNMSGSQEHHMFLDRRLYITLIIVFVISPLCFKRSLNSLRYASMIAIVSVAYLSGLIIYHFVNRHQLERGQVYFMVPHGDSQSHSPLTTLPIFVFAYTCHHNMFSVINEQVDKSFKVIRRIPIFAIVLAYFLYIIIGGTGYMTFGENIVGNILTLYPNSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNIIIFIENFRKGKLYDNRASFIPLDNFNSEDPQEAPTQQNNEEPNLRSESLRHINIITLCILLFSYLLAISITSLAKVLAIVGATGSTSISFILPGLFGYKLIGSEFTGTNERVPTSIKIFKYLSLSLFIWGIAVMVASLSAIVFLGTSSH
The following text describes a protein:
Function:
An alpha chain of antigen-presenting major histocompatibility complex class II (MHCII) molecule. In complex with the beta chain HLA-DRB, displays antigenic peptides on professional antigen presenting cells (APCs) for recognition by alpha-beta T cell receptor (TCR) on HLA-DR-restricted CD4-positive T cells. This guides antigen-specific T-helper effector functions, both antibody-mediated immune response and macrophage activation, to ultimately eliminate the infectious agents and transformed cells. Typically presents extracellular peptide antigens of 10 to 30 amino acids that arise from proteolysis of endocytosed antigens in lysosomes. In the tumor microenvironment, presents antigenic peptides that are primarily generated in tumor-resident APCs likely via phagocytosis of apoptotic tumor cells or macropinocytosis of secreted tumor proteins. Presents peptides derived from intracellular proteins that are trapped in autolysosomes after macroautophagy, a mechanism especially relevant for T cell selection in the thymus and central immune tolerance. The selection of the immunodominant epitopes follows two processing modes: 'bind first, cut/trim later' for pathogen-derived antigenic peptides and 'cut first, bind later' for autoantigens/self-peptides. The anchor residue at position 1 of the peptide N-terminus, usually a large hydrophobic residue, is essential for high affinity interaction with MHCII molecules.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Autolysosome membrane; Single-pass type I membrane protein. Note=The MHCII complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation. Component of immunological synapses at the interface between T cell and APC.
Domain:
The alpha-1 domain is a structural part of the peptide-binding cleft. It contains one alpha helix and 4 beta sheets, respectively forming part of the wall and the floor of the peptide-binding cleft. The other 4 beta sheets of the floor and the second alpha helix wall is formed by the beta-1 domain of HLA-DRB. Forms hydrogen bonds with the peptide main chain via conserved amino acids. The peptide-bound alpha-1 domain forms hydrogen bonds with CDR2 and CDR3 alpha-domain of TCR; The alpha-2 Ig-like domain mediates the interaction with CD4 coreceptor.
Sequence:
MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIKGLRKSNAAERRGPL
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MSMKGIRRILSFHGPWPTATPSSLSPSSPSHPLPSSAPSSPNADHSYASDLIHEMTENITRAEPVIHEWNVTGLETTTASDRNTPESSLFHDKNRERARLFLDSVMDVNHSMHYFSASSGATSRHQLVRAQRLMETAMKRLQKEFFQILSSIRDRIEIINSSGGDDSVSAAMGELRAIAECMVSSGYSKECVRVYQILRRSVVEEGIYNLGFHRMNHSQLQKLDSDAIGNRIKIWIEASRPIIQTIFPREKLLCENVFGSCSHLIAESCFAEISRDLAINFFEFPEMIVKVEKKRSLEKVGDHYIDLYNSISILLPDIQSLFKCPKSSTVLIQVTTSVNKLSKSIQSSSPHVNT
The following text describes a protein:
Function:
Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization (By similarity).
Subcellular Localization:
Cytoplasm. Cell membrane. Cell junction, tight junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with GTP-bound CDC42 or RAC1 at membrane ruffles and with PARD3 at epithelial tight junctions. Recruited to the centrosome by a microtubule and dynein-dynactin-dependent mechanism.
Domain:
The PB1 domain mediates interactions with MAP2K5; The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases; The PDZ domain mediates the interaction with CRB3.
Sequence:
MARPQRTPARSPDSIVEVKSKFDAEFRRFALPRTSVRGFQEFSRLLCVVHQIPGLDVLLGYTDAHGDLLPLTNDDSLHRALASGPPPLRLLVQKRAEGDSSGLAFASNSLQRRKKGLLLRPVAPLRTRPPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQRNNVVRGASGRLTGPSSVGPGPTDPDSDDDSSDLVIENRHPPCSNGLSQGPLCWDLQPGCLLPGAGSSLPSLDSREQANSGWGNGMRGDVSGFSL
The following text describes a protein:
Function:
Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPTKPIHLTAFLGYKAGMTHIVREVDRPGSKVNKKEVVEAVTIVETPPMVIVGIVGYVQTPRGLRTFKTIFAEHISDECKRRFYKNWHKSKKKAFTKYCKKWQDEEGKKQLEKDFNSMKKYCQVIRVIAHTQMRVLPLRQKKSHLMEIQVNGGSIAEKVDWAREKLEQQVPVATVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYQIKDGKLIKNNASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRALEKIDLKFIDTTSKFGHGRFQTVEEKKAFMGPLKKDRIAKEEAA
The following text describes a protein:
Function:
Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine.
Subcellular Localization:
Nucleus.
Sequence:
MDLSTIPTLRHSIDNILGRSAAVPRWQGRPGTERKDTCSPVGPIDYSLHSLASQESRSAQEAQDTVEISDTTGRFFASEDVRSPGDNDVATDVEAPDGDVTDADVFDVGGDSASETGRESVCSGGTDASVSEEGSDRRVKRMRRVRTTFSAEQLKALEDVFKVTHYPDVHTREQLARKTKLPEARVQIWFQNRRAKWRKYEKLTNFGGLGFLQNTDMAMVPAPHTAAITRVDPKDKTKERPRPLQPGSPSINPVLPTIHSVTVPTTLYTSPIPSCTIVPIGFPTTPDSETRRCSSIAALRMKAKEYEAALGMQFMYNKQ
The following text describes a protein:
Function:
In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
Subcellular Localization:
Nucleus.
Sequence:
MVHVYKGLFLECDPPTKQFVEYISKQEHFEVIVLDETHLFLQAADEKIINTIQRRIDDLQNQNTYSVFDKDQ
The following text describes a protein:
Function:
Involved in 3' mRNA processing. Positively regulates poly(A) synthesis.
Subcellular Localization:
Bud neck.
Sequence:
MSLPVTPVKSKVCSTLSIQHEMDHDQCRDVLCPRENLLAINRTNNIESVAIPRQRSSKNKKPHEHTQSQVRFSIPDPNEISQDSPLKIVFPKSGNETERRMSTSSLLMNSHGHLVDMHSKILVDVPKEVWKFHHNRRKKCESRHRKTRSDVRSNTSSSGKEPNHSRSKSLQSIIVDTMNTYRATEVETSINENTSNISQVSPLNLSFDRPPPLTPEKNLYLTPESPLNRYHLPVPLEISLPPYLSPQNKDKKRSSLVYDGDGYSQFQEGNTSSSTESSLEQPSSSYSDEDDSIPYAHHDVSFELNNADADKLLGIDENANVNLKIQRRNLKNPQHIKSKTDRECEEKNTEKNVSLKILSTPNKLIDIPDLEHMKSPPSTGLNGTLKFFQQFEPSEEPTSPTRQVNPESLDKLDMSFKFPSSTTNNNVDKVHENRNSGDTNNEDFLKVDTSPVNQSFESRRQMLIDLQKSPTNNNPRIHKHRRSRSVHNIDDISLNFEATSTPPAPTSAPSIPVEHSNPCTSIEIPKRSPLRFTSSPKTSDIPPEAQSPKNGSFLQEISVPSIQIIPDESISHTREPSPSLIECPEDENEAFSTEVADHSIAIISETKSVPSIEPFKPLSSFNSFGQEIQNKEPTPLNQTPTDLIGKQRNCVNPHSIPFSVLSSNSQSSQSGSSKSSYNSEFSSNTAITDTTSQPSVTINRSTLEHNFIEEKRSIKNLGHGPPSQKNNYSFPRNKNTPSNRHDLDFNTIYEKRDGKMVEVILLDEDEDVGLKNNDISRTRVCHAQKAKNEQQKKRLSHCNEILGMCDKTADDAKRIIYQLVNEKHKFSEKGQQTKPKKSRVLPPLPFPLYDEKGNSLIPNKYQSSIHNDIPSHRKLK
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
Subcellular Localization:
Cytoplasm.
Sequence:
MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGGRLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAAQWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD
The following text describes a protein:
Function:
Acts coordinately with phospholipase atgl-1 within the lipolytic cascade to distribute stored energy to tissues to maintain energy levels during the dauer phase. Localizes atgl-1 to lipid droplets, possibly to facilitate triglyceride hydrolysis. Regulates lipid droplet size, lipid content, the exchange of lipids between lipid droplets and fusion of lipid droplets during the dauer phase.
Subcellular Localization:
Lipid droplet.
Sequence:
MFQKTDFLSKIFSSSSHPLTGSQNIVVKDPQTLDFAMQSQNEIVCSLRERSHMNTMSYAQTQMMAIDEIRAFQSEGHLHLKYISLIIAMMAETAVVTSRSWFPYFSCPSKSQRLAEAEGRILSALGIKYLARLIQIPFKNTEISTITVNCESEQPIVKAKYPIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFSSDPETAETEMIDSIEQWRDKMNLEKMNLVGHSFGGYLATSYALKYPKRVENLILADPWGFNEMDPEFAQKLTSRQKNIFWVIQQFNPLAVLRLVGGYGPSLVRRLRPDLALKYSEDVYDYIYLANSRDPTGEEVFKCLSENLGWAKQPMSKRFHELDNTVPVTFIHGERSWIDWRTTRRLFGELEHVESHIMDSAGHHVYADDADKFVQLVIGSLKDGKTGELVPEEVNLEEEIVTPI
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MSRLEKLKEKRREGQKPQQERKSVKTTPSEPRSHMDYTIEETENWHKKQRVDGSENVDKLAESTYYKDISAIKVDLQAYREGKAADPTELTTILAANTERKTKRKRHAKDADADSYINEKNKQFNMKLNRQK
The following text describes a protein:
Function:
Chemotactic activity for neutrophils and lymphocytes. Binds to heparin.
Subcellular Localization:
Secreted.
Sequence:
MRVSLAALAFLLTLAVLHSEANEEPAGNMRVCCFSSVTRKIPLSLVKNYERTGDKCPQEAVIFQTRSGRSICANPGQAWVQKYIEYLDQMSK
The following text describes a protein:
Function:
Represses the expression of non-poly(A) mRNAs like L-A or M viruses and is therefore involved in antiviral system. Mediates interactions via its N-terminus between the exosome and the SKI complex which operate in the 3'-to-5' mRNA-decay pathway. By interacting with NAM7, is also required for nonsense-mediated 3'-to-5' mRNA-decay (NMD). May recognize a stalled 80S ribosome at the 3'-end of a nonstop mRNA which leads to the recruitment of the exosome and SKI complexes to the mRNAs to be degraded.
Miscellaneous:
MISCELLANEOUS: Present with 233 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal domain (residues 1 to 264) is required and sufficient for interaction with the exosome and SKI complexes and for 3'-to-5' mRNA degradation.
Sequence:
MSLLEQLARKRIEKSKGLLSADQSHSTSKSASLLERLHKNRETKDNNAETKRKDLKTLLAKDKVKRSDFTPNQHSVSLSLKLSALKKSNSDLEKQGKSVTLDSKENELPTKRKSPDDKLNLEESWKAIKEMNHYCFLKNDPCINQTDDFAFTNFIIKDKKNSLSTSIPLSSQNSSFLSLKKHNNELLGIFVPCNLPKTTRKVAIENFNRPSPDDIIQSAQLNAFNEKLENLNIKSVPKAEKKEPINLQTPPTESIDIHSFIATHPLNLTCLFLGDTNAGKSTLLGHLLYDLNEISMSSMRELQKKSSNLDPSSSNSFKVILDNTKTERENGFSMFKKVIQVENDLLPPSSTLTLIDTPGSIKYFNKETLNSILTFDPEVYVLVIDCNYDSWEKSLDGPNNQIYEILKVISYLNKNSACKKHLIILLNKADLISWDKHRLEMIQSELNYVLKENFQWTDAEFQFIPCSGLLGSNLNKTENITKSKYKSEFDSINYVPEWYEGPTFFSQLYLLVEHNMNKIETTLEEPFVGTILQSSVLQPIAEINYVSLKVLINSGYIQSGQTIEIHTQYEDFHYYGIVSRMKNSKQILETNTKNNISVGLNPDILEVLVKIHNTEDFTKKQFHIRKGDIIIHSRKTNTLSPNLPNTLKLLALRLIKLSIQTHALSDPVDLGSELLLYHNLTHNAVKLVKILGTNDISINPNQSLIVEVEIIEPDFALNVIDSKYITNNIVLTSIDHKVIAVGRIACQ
The following text describes a protein:
Function:
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules and the mitotic spindle poles.
Sequence:
MEKLQILTERQQTELNHAIIQYLQPLCQQDNHVLLDQLSKLLNIDQSTQESNNVEKVDNYLEKRWSTVLRLQKKIIDLENEISNLNNIINSTNSDNNGIILSKDKINWIPKGAVKQSYQCENIVTTVKLHPNLPLVLNGCNDGNLYIWNISNDDNTIPEKMIKAHTRAINKICFTYKKPYYLATCSSDLTIKIWDEKFNHIRTLNGHEHTVSSIQFSPVDNSILYSVSRDKNIRVWDIFQGISLKSFVGHSEWCRDLDIISSDTYGDFVLTCSNDQSARLSHANSGAGVAMIVGHSHVVETVKFLPSLQANKILDEYITKNTEQFPTIPLELLKDKTYNQLGFKYCITASRDNTIKLWLIPPPTIAPHRPPLPSKYNNSQSWLIAELKGHSSWVKSLCVHPNGKFIISGSDDKTIKFWDLSGLLETGYVNVVKTIIGHDGFINDIDFARLKEASDVSEEDLLKQVEKRMRCLFISGSADNSIKLWN
The following text describes a protein:
Function:
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Sequence:
MIPRWIQLVGCLLLALMLPPSAAKKDKPGISFHKLHEKPYSMFYFEKSDTVLLNLEDGEVLRSFDAGENWEVIEDNGMKHGVTSIHQHPFDEDKAYALGDDGKHWITTDKAKTWKSFKVPDQAYFKSPQTGPLTFHGRDSSKVIFETRPCPSCAPRSYYTTDDFDTIEVLTESAVGCYWAVGNPQFAAGPNMPKGMEERTVCVVPGLKASSRFAFRLVYSDDYFRSQGIETKLQDGRPVSGVTSIAQVKSFIVAAVESQGTTERALYVTTDIEKWHRAEFGDHRLEQDAYTVLESSDYSLQVDVLTNPFSGMGVLFTSNSDGTYFTRNIEHTNRGPRGYVDFEKLAAIQGIVLVNTVRNPDDVEAGASKEVVSQISFDDGRTFQPLKSTDGQRIHLHSVNSDTNLGRVFSSPAPGLVMGVGNTGDYLGKRSDGHLYVSDDAGLTWRLALKGPHKYEFGDQGAVLVAISEAPKVKKIEYSLDHGKEWKSVDLPHEVDGETSTLTTTPDSTSLKFILLGHSKGEPSVYAIDFEDLHERKCEDEDFDNHWPARLDEHGEPDCLMGQKQFFRRRKANADCFVAEAFNSSMSKFEPCKCTVEDFECQSTRTEDGKDCVPPKSFTPPDGDCINPDDTTMIPSGWRLIPGDVCVRDDGVNLDKDVEIPCKDVNNRPKSKEITSTMKMFSSGLSAYRYLERQVSNLGEDETVLMLSRNQELFVSHDHGQTWQQELKGASIMKIVPHPYNSDTAYILTDSEEVFYTINRGATFGSFRAKTLPDYENGPILRFHPLKRDWLLWVGTECDSGSCHSNAYFSDDRGDSWKTILRHAKKCEFEYKENRPDSLYLVFCEQYENEDDKKRLQLMSTTDERFSDWETVEENLVEYATRAEYIILASHTDKDNALKARVSVDGTTFADLKFPPNVVPAQNLYTLVDASEHAIFLNGTTYVLSLDAVNQNDWGYVDFERMQALEGVIIANIVSNVDELSDGAPKRLRTMITHNDGGEWTLLAPPTKDANGKKFPCSVVEGKGTEDCALHLHGYTERADPRDTFSSGSAIGLMMGLGNVGDRLTSKDEADTFLTMDGGITWKSVKKGRYMWEYGDSGSVIVIVSEQKSTKVLHYSTDEGATWQDYYFSDEEIEVIDISTVPSDTSKKFILWGKKSDELVTVNVDFSGLYDRDCEFDDKGGDVSDDYQLWTPKHPFQEENSDYECDYNYERQNDGTCKLVPGLKPHDPVGYCKAHPDAIEYFEPTGYRRIPQTTCQGGYNLDHQTAKPCPGKQQEYDKKHGISGIGLFFAIVAPIAVAGAVGYYIYTKWDGKFGQIRLGETSTGTQGILSRDSLLVTVPIAIIAGIVAVAKALPLLVTSLWRSASGYMRVGNRSYPRPYASRASFAARRGDYSSVVEDEDELLGVVDFDGDEEEDS
The following text describes a protein:
Function:
Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7).
Sequence:
MQDIYGTLANLNTKLKQKLSHPYLAKHISAPKIDEDKLLLFHALFEEADIKNNDRENYIVTAMLVQSALDTHDEVTTARVIKRDENKNRQLTVLAGDYFSGLYYSLLSEMKDIYMIRTLATAIKEINEHKIRLYDRSFKDENDFFESVGIVESALFHRVAEHFNLPRWKKLSSDFFVFKRLMNGNDAFLDVIGSFIQLGKTKEEILEDCFKKAKNSIESLLPLNSPIQNILINRLKTISQDQTYHQKVEEG
The following text describes a protein:
Function:
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Sequence:
MLDEGDPDPDPVSILQTIENEHEDLTDDKRKEIKLIKTELWFLGRFLLGHWECSKSLQVRIRSLLVFAEDLYRSNFDADPSYVLRSIEHFNYFIPINYWESEESLVPVTTPLNHVHMLAYIDNVVQNFKDLLIVRLVKLPDVQSQVESVVKELRALKKFIFFLGEICISTEQIKCWQTFWLHVRLVTTRAAILLYLPCYDRFSHMMQDNLMCSQIVCDDELLKYILKLLSFGSTHVKLYLNKAADEFMDFLLHVHMQLGADSWTSDQNYTFTEQINCLRALLKELPLINDIQDEMRIHFFKRLVTLVIHAGLTVYSGGDWDQKMLLLYGMIRSVKTEICHKIREWVTSHLPKNDKLGFSNCLLASLKEFLSGHSASLASVKDQIEVVHEELKFFEPFIMRLAEQANNKHNELQNLVGRVIDKAYEVEYILDSFAISDVPLTFLRMWLLEIIREIELIKTELTKPKEKNMTSASHATDGELVGFTDVCKTIRDQLVGGSQELDVVSIVGMAGSGKTTLARSFINDDIVVSHFDFFAECRVSQEYTREDLLFSILSSANSGLTDISKRGADILADRLRKTLLPKRYLLIIDDVWAVQAWDDLRLCFPEAKKGSRIILTTRLKEVATYAKCVTEPINLRSMKDSESWLLLQKKVFGEEMCPEELKEVGQNIAFKCNGLPLSIVLVAGLLAKIDKTERCWTRMELSFGERVQDGAKDLVKLSYEDLPNKLKSCFLYFGAFLEDREISVSKLTSLWIAEEFIKNNEDKCLEDTAEDYLSDLIGRNLIMVSKRRSTGKIKACRVHDLMLDFCKEKAKEDNFLLWLKRDRDSNPPRFYSERPMHRRLSFYSNRDDLSEWRPSCSHARSILFRELSDNACSSMRHASFIFGNFKFLRVLDLEVVDVDSFPTELNQLRYLAVQTTKNSIPSSIENLWNLQTFIVKRNGGQVWLPDTFWKLSKLRYVSISDGALFASRGAQESCGGNFLKLDNLETFSSIYVSRVNNMERMVRRTPNLRKLRCVFTDLGRWGKNENRFPVLDSLSQLETLKVVFVGISEVGPSRLNFPENLKKLTLCKFPLPPEEISTIAKLVNLEVLKLRQVAFEMGEWEVRDQEFSQLKLLELENLKLSKWEVSEESFDRLEKLVLHGCLHLKAIPDGFQDLNCLRYIEVKSCSEDVADSARIIKETREDNGQKCDVKIFS
The following text describes a protein:
Function:
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
Sequence:
MRNEVQFELFGDYALFTDPLTKIGGEKLSYSVPTYQALKGIAESIYWKPTIVFVIDELRVMKPIQMESKGVRPIEYGGGNTLAHYTYLKDVHYQVKAHFEFNLHRPDLAFDRNEGKHYSILQRSLKAGGRRDIFLGARECQGYVAPCEFGSGDGFYDGQGKYHLGTMVHGFNYPDETGQHQLDVRLWSAVMENGYIQFPRPEDCPIVRPVKEMEPKIFNPDNVQSAEQLLHDLGGE
The following text describes a protein:
Function:
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
Subcellular Localization:
Nucleus.
Sequence:
MSSHTNLPSPKPVPKPDHRISGTSQTKKPPSSSVAQDQQNLKCPRCNSPNTKFCYYNNYSLSQPRHFCKSCRRYWTRGGALRNVPIGGGCRKTKKSIKPNSSMNTLPSSSSSQRFFSSIMEDSSKFFPPPTTMDFQLAGLSLNKMNDLQLLNNQEVLDLRPMMSSGRENTPVDVGSGLSLMGFGDFNNNHSPTGFTTAGASDGNLASSIETLSCLNQDLHWRLQQQRMAMLFGNSKEETVVVERPQPILYRNLEIVNSSSPSSPTKKGDNQTEWYFGNNSDNEGVISNNANTGGGGSEWNNGIQAWTDLNHYNALP
The following text describes a protein:
Function:
Component of an histone acetyltransferase complex.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MPPKLTALQPPSPSPPPPTNDAQDLLVIQDIMDTLDQIPPELTRVHSDLNELGAVLYSTLVSLEKKLYTLIDWIQDPNVTPEKRFELLQEIAEEAARYKLGGDDKIRVAAGACDGILNHQKHISNLLASSTLLVPSPPSPYSQSLTLPFPQPVTNSRRVARAANSPFGSRGYTANGGPSETKVGDTPSKKKRSRVQQLGARDDDESSSAGGEKKKPVKRRKQNRATSPTDSVVSNSGFGGKPIEPRTARQLAAAANRARREADDGGSDTESRTGNDEKRSNVPMQPSFSIDSKRTDGLGLDTGSREGSGVRSANVTPTLGYAAVMPPTAELKRPSRRGGKRSSTNIPAAEEFEEEESEGYGDDDRSKRGERYAEMEMGEETGGAGDDLDSKVYCTCRQVSYGEMIGCDDDDCEIEWYHIGCLGLDKTPAGNWICPRCIERRKKQPRGKKGTRGKARK
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSVFTETPLYLKLIYKLTGVYHNSGKNNFFSVVTSIVWCLPFYSYFIYLCIDFNLLSHTSSDVFVYIEFCSNLSTIMFTTISFFVFNVRRNRIRALLKKVKNLRLGVISRSTKPNWPRMALIGSIVVNTALIPFKKCAKINYTIYTWFPALISTSEVMYLNVVLNYFNEKFDSINHNLQNLLITSFLLTQSDKLKSYEEDDTNYEIQHIQDLSLVHYKLVQQVSEFSDIFGITIILSLILWFENIIETFYFLIYMMVNGSDSLIYESAVYGCYVVFAISWMFILIFSFSTVQNKANATVIYVHDIGNKYLLSGKMNVKTQHLSFISARLLSMKLQFTALHFFNLDWTFCHMLVAAVATYVVILVQFRI
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MTIPFTPRRSTRGQVFTPSPFPTPRISHPDTKYTWLSAASTPRLSPGGSKTRTHYTAFSKVFAKGGKKNAAPKMTKFAIGDGVLVSVEGGNDGVAVLIDLWEEERSEDDEEEDEEDEDGEEEKSPLMMAEVHWLLRRQDLPDVRRNFKVDDNEVLLTASSTRRVTATIPISLLDDTVPVLSRTEFREKYPEEKSHYRGWAYVKEGIYWCQRAFDRFAKGQNCWKIDIEEWKEVGKRGEGWTVPISKEEEEHPQEPGLESSDESDDGSEARVEEESDGDEESEEESDDPAESISKKRKRPTKTAKTYAKRGRKVVTASRSKLPPRSKATPKSRKATKKPHPATSTSFLPTDFIAPELLPTDPFERALRMLHVGATPESLPCREEEFVDVLSKVEEGVESGGGGCLYIAGVPGTGKTATVHAVVKELKRKAEDGEIPPFSYVEINGLKIPAPQHAYTVLWEAISSSKGVGAKTALKGLERHFGKKGGGARGPRGHTFVVLMDELDQLLTSKQDVVYNFFNWPTMRDSQLFVIAVANRMDLPQQLAAKIKSRLGLQTILFEPYDRAALVSIVQSRLIPHPLMPSQDPKVLLPDAISLAAMKMAGTNGDARRVLDACRRAVEVALENKSKPPSATPTAPPPQPGPQPVSAKAMAAVLQAMSSSPTTKFIQACSLQQKLMLAALVRCVRREGVAEIVWKNIRNDHDALMRSLAFDTSEQGGREVAPNLLSNSELALVLTSLTSSHALVCSADISKGIDERKIALGMEIGEVGRVLMNEGDSWRKALAGV
The following text describes a protein:
Function:
Transcription activator that acts as a flowering master switch in both long and short days, independently of the circadian clock. Promotes flowering upstream of HD1 by up-regulating FTL1, FTL4, FTL5, FTL6, EHD1, HD3A and RFT1. Seems to repress FTL11 expression. May recognize the consensus motif 5'-TTTGTCGTAAT-3' in target gene promoters.
Sequence:
MSNLSSPSGEASASSNQQPSSASTNPTPVKRKRNLPGNPDPDAEVIALSPKTLMTTNRFVCEICNKGFQRDQNLQLHRRGHNLPWKLKQRSKEVRKKVYVCPEVTCVHHDPSRALGDLTGIKKHFSRKHGEKKWKCNKCSKKYAVMSDWKAHSKICGTREYRCDCGTLFSRRDSFVTHRAFCDALGDESSRVVTAKPTAATHHPHQFSHPAASLEPFPLHQTILQTQFPPEQQKHFNIRSDIPPWLNCQATTSLGHLDFPCSIYSTRLEQEYPPGNTGALPPPPAPLPAYQVSASSPHMSATALLQKAAQMGATISRPPQIASFGQVSAPPPLLHDMMMNRLSAPPGSQGKDEGGRGGGGGNDGMTRDFLGLRAFFPQGYP
The following text describes a protein:
Function:
5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. Specific to 5'-phosphorylated single-stranded guanine-rich sequences. May play a role in RNA metabolism, ribosome biogenesis or initiation of translation. May play a role in regulation of transcription. Interacts with tRNA-Tyr.
Subcellular Localization:
Cell projection, axon. Cytoplasm. Nucleus.
Sequence:
MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLYGRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDESHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPASEIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQPASKEQQASGQQKLPEKKKKKAKDPWLR