lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Essential component of the RMI complex, a complex that plays an important role in the resolution step of homologous recombination, in a process called Holliday Junction dissolution, to limit DNA crossover formation in cells. Together with TOP3A, is essential for the resolution of meiotic recombination intermediates, a step that prevents entanglement of the parental chromosomes.
Sequence:
MRRRRLQLRYSSDEEEEDETGTSGVGDSVQSFGIASSIQPETSVSSNSNPNPGERIAISEVEIIDVFGNPQPTPPDSSIPTPYPVYPSESVSGNDYESPISEVLSRMGIKLKREWWVSCLSGLETSIPQFSYLDVAAKAKHCFEQFMFFDMNLCGGGVLPPNVASMNRIELAGPFVLQVDEIVNIGCPLKGRYENANAGLKRCLKLSMTDGVQRVFGMEYRPIKDLQVLAPAGLKIVVSSVQVRHGLLMLVPEIVEVLGGMVEELEEARKRLVVEVNKPPRGKRTRVGVVPSLTTRATLAAWSLNGNDTGNHVHDTGNHVNSSASGNASHTQANQGIPVHVTRTHNSSRAMDEPLASTNVGATVSRVEHMQIDTASAHGERTFSDIHSTSSNIHRAASTAGTGTSCSGACSGARSFANNVGGNSLDQTSNVTSFVEEMHIDTGRVRDTTTHIYGSDSGGVAAEFSNMVVDLEGPSVLSTNTEKPFTYLAELSQKWAVMKDTIHFVQGRIKCFLTGVKKFQFKQQSTYELLCYVDDGSLICEILLHNDVVQKRIGHSSMEVTAALSSSAPTSLNAMMKEKLKRFQLFLADFEGIMVVEMNRSSQYPVAIEMNQGCSLTDARLLLDRIKSSSRTSSSLNPVVVLSP
The following text describes a protein:
Function:
Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
Subcellular Localization:
Cytoplasm.
Sequence:
MKLSIHGRKITLTDAIRKYAEEKISKVEKFNDSIIKIDATLAASKLKTGNAHVTEILAYLSGSTLKATATESDLYASIDKAVDIMESLLKKHKEKRSRAKVQDDTRKKSYSFDYIVEPEEKLSDEKKLVRVYLPLKPMEISEAILQLEYLNRVFFAFTNTTTGKMAVVYKRKDGDYGVIED
The following text describes a protein:
Function:
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Subcellular Localization:
Nucleus.
Sequence:
MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVKYVFRTENGGQVMYRVIQVSEGQLDGQTEGSGAISGYPATQSMTQAVIQGAFTSDDAVDTEGAAAETHYTYFPSTAVGDGSGGTTSGSTTAVVTTQGSEALLGQATPPSTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKNDSN
The following text describes a protein:
Function:
Photorespiratory enzyme that dephosphorylates the 2-phosphoglycolate produced by the RuBisCO oxygenation reaction.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MEALRTRASAQPLQDADDLIDSVETFIFDCDGVIWKGDSLIDGVPETLDMLRSKGKRLVFVTNNSTKSRKQYGKKFETLGLSVTEEEIFASSFAAAAYLKSINFPKDKKVYVIGEDGILKELELAGIQYLGGPEDGGKKIELKPGFYMEHDEDVGAVVVGFDRYFNYYKVQYGTLCIRENPGCLFIATNRDAVTHLTDAQEWAGGGSMVGAIGGSTQREPLVVGKPSTFMMDYLADKFGIQKSQICMVGDRLDTDILFGQNGGCKTLLVLSGVTSLSMLQSPDNKIQPDFYTNKISDFLSLKAATV
The following text describes a protein:
Function:
Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation. Required for transcriptional silencing in the outer repeat (otr) region of centromeric repeats and the Tf2 long terminal repeat retrotransposons.
Subcellular Localization:
Nucleus.
Sequence:
MATFTPLNAASEDLDKEKRTLEIRIEEAVQIYQNALSAQKQGDDNAATKYYDELLNVRILRELPFTVNSNYKKNNALLLLHYLTRKNHGLFLLSKLQSLLSLDPSTDPIPVYRDALLDFAIALACDYNDIELWSFVAELAEKLEMPRIQRFALESSFYTGYEPFDAERVFTNIDDLNPGKLISLQNLYNLLKKLGGIAEPLPQLDLSISSLYTLPSFFPQLPTPSFHRRSINLCPKIKKLQLSHDTLHGFLDLVLYALQINEKKTPTRGFPSTLIIHVHSLNLSTAESHDLESTDSELWSEISDAGPDTNTINTAAKLSEPVYAKDIVPPPSDNLPKPQLLKRPIDDSDVRISKRSRGRDLRTPSESNLFSLIASITSDINEQIQKRFPDATSPFSGESMFREYSSIFEDYHQLLVNFPSEGSIPDLDVSTDSAANGAFSKMILIDLAMHSANRLEHMQVPDGYLLQLLSEVNSLNMVPAELATFFVESMLRPRKLEPPFYLQQCWGKIFKKKFTTICERIESTLHELVKASLQTPEVFNISQSLFELFLDDYFLALKFSSNDQKDDNVSEIPTESLEYKKLRCLRWKSLTEQVVELQPSCKSSSQRHLIIRNSWARNLLLRLTGCSSEAIVENFKQLRCLLQENSDSLELLNSQCMADLSVQVVDFELSKLQTVEFFNTLFMNTKNLDFNAVIKNLEPVLSPENKFAEDPQAKFISQFLEKTSTEFQIHLWYLLYQAYSSAHRPYNSLLCAFQSLKIILIRLCSSSFSIQDAGRRQAELLGMLNFSSNLFRIIWQKLHEQPDILSPCNEMTVIDCIRIILIYLRTFAIYVGIDEDISDQRIPKPSNPEFDSYAQTVKDSLMSGWCIFYTLFAHLLHYDFIKADAQKLLPQILTAIHSQYSFRGYCSSSNQSFLELSQTECQRLDAWENENEILQCVCCRFNLIIGSEYYVPQSHQSDSVNLTSNDAIKIIPFILGFAVKRSHGWVMPRSDQKNALEIICKVIRFPGENNADVYFNKCAIKEFLERDISPQLTKMLLKSNDILGLREIGSKVVDDRVRGLYYAQSQVLFGYYRSRLKGSRCINDLLVIIKYFLLDLYLNPRRQDSWYTCSSVFSSLADEELGWSAEQICLADDVINEYRRKAILCNLMALSLPFTQDKLFKANVYFDFAMNLYASARPPLEMAAFLPSETRVFSGASGLYNLSMKPIEVSKVIALAADYFGMSAELSNDWRALYMLGKACRKCGDMENALVHFEAAAALAPTKSGSGSQQALLIEPHYALLSNLSKAAIEGSVEIVQILSYLRRIRHPPKDSGSLLEVKNEDVNIYKRNALLFILKALAEMRILDKQSWHHRPTYRIAKIMEHLGNVQQAKEEMETLFSYKTSGKSLLNIWRTPNERPGRHFYYGATYSRYLLSLFYKTNDKVNFLQFLKRFRRSSSTIYEHRQIWLDIMIKYLEDLRLQHSVKETQINDLPLVEFKYVYKEISLLDEQKLSLLHQVYEIRKLNNGLYPTIKVDDFLIDCFMSLYNEVKSSISPLDANIPNSPSTITAKPLNDEKAINNENSVKQKTVITRKDVVSKVLALFRPHRETYYRETQNKILQKLASTSSSLVRSFTEDSSQAGESPGIHEEIQ
The following text describes a protein:
Function:
Fatty-acid-binding protein. Interacts preferentially with saturated fatty acid. May be involved in alpha-linolenic (C18:3) metabolism.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MVSFRFPFSFSQPPRATTSFSGFSISAVAVSVTVGAAAAGAAIAASRNPSHPILEWAFSSHRSSLSPWGSITLADESVVEPKTGFSFPASIGDSRRLLGVGLRKKSLLGLKNIDVYAFGVYADCDDVKKLVGDKYANLPASEIRGNKSFMDDLMEADIKMTIRLQIVYGKLNIRSVRNAFQESVGNRLKKFGGSDNDELLQSFTSLFKDEYKIPRNSTIDLTKDPGHVLSVAIEGNHVGSVKSHLLCRSILDLYIGEEPFDKNAREDFLDNAASLAFDN
The following text describes a protein:
Function:
Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DAB1 and IRS1. Specifically recognizes and binds phosphorylated proteins via its SH2 domain, promoting their ubiquitination. The ECS(SOCS7) complex acts as a key regulator of reelin signaling by mediating ubiquitination and degradation of phosphorylated DAB1 in the cortical plate of the developing cerebral cortex, thereby regulating neuron positioning during cortex development. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Also inhibits prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Nucleus.
Sequence:
MKRLTLKNLKRSLHHQSKQGGGEGGEGIEEAYNSDSETACREEDSDESAEVPGRRLRRAGTLPYPSRRRREREGFMSTIRHRLKIGKGSQDQENCTEEVKDEEKEDGEVVEEETVTTRRPTRSKSMRVRKKESATTVALRPANSEENLSQRKDSQYWTRKLHEKNRKDLPPAPHDGEGDENGEITMDICHKKVERKDSSDSRSSKSSKSKNSPFSVSSINCTQEKPISSEKSRLKALRSFLTLPRRGSKKKGSKEKEEPDSPDTISSNGVSPRALPPCPSLTESHDIFNSASSTVPRPRNGNNGSSYEPYDDEDNERKIASYEQVGGRAHVNHSLTEELRKLVRHGWYWGPISRAEAEEKLAHLSNGSFLVRDSSDDRYLLSLSFRSYDRTFHTRIEHCNGIFSFYSQVESEGHKSIVDLIEHSMRESQSAVFCYSRSRTPGAPSFPVRLTNPVSRFTQVRTLQYLCRFVIRQYTRIDHIQLLPLPTKIREYLQECHY
The following text describes a protein:
Function:
Acts as an inhibitor of mitochondrial fission. Interacts with MFF and prevents DNM1L recruitment to mitochondria, promoting a more fused mitochondrial network.
Subcellular Localization:
Cytoplasm, cytosol. Mitochondrion outer membrane. Note=Predominantly localizes to the cytosol, with a minor fraction at the outer mitochondrial membrane.
Sequence:
MPWKEESEFTKQDKAARVIQQAWKSFLNVAIFQHFKSLIDLRRQGEPRQIVKYINPKEAELLDAAAGIHVRFRLGGVKFPPDIYYKIFTHRPIEDLCANSPRNYAKLPAKHTSHNKNDHLQEEDHSGWYHRIENNGWRPVSDTFWLSTDGMVVEDKKESEFHFSKLKRRQDLEKKRKLRKIEWMRQMYYSGSLEAKSTHHETLGLIHTATKGLIRAFEDGGIDSVMEWEVDEVLNWTNTLNFDEYIASWKEIATSNSSANFKGFRFNQAQKNIYNYGGDISKMQMGIPDDTYYENVYQEPNVTRLTPDSTYGL
The following text describes a protein:
Function:
Putative regulatory subunit of serine/threonine-protein phosphatase 4.
Subcellular Localization:
Cytoplasm.
Sequence:
MHPPPPAAAMDFSQNSLFGYMEDLQELTIIERPVRRSLKTPEEIERLTVDEDLSDIERAVYLLSAGQDVQGTSVIANLPFLMRQNPTETLRRVLPKVREALHVAGVEMQLTAAMSFLTILQDESVSIHAYTHSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKAQLSQTVQSRLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCEKSFKADESILISLSFHLGKLCHGLYGIFTPDQHLRFLEFYKKLCTLGLQQENGHNENQIPPQILEQEKKYISVRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRYTIAICFYEVSKLLNSGVYLIHKELITLLQDESLEVLDALIDHLPEILELMSTGGESSVQENKLSSLPDLIPALTAAEQRAAASLKWRTHEKLLQKYACLPHVISSDQIYYRFLQRMFTIMMTNNVLPVQKAASRTLCIFLRYNRKQEQRHEVIQKLIEQLGQGKSYWNRLRFLDTCEFIIEIFSKSFFCKYFFLPAIELTHDPVANVRMKLCYLLPKVKSTLKIPADKHLLQQLEMCVRKLLCQEKDKDVLAIVKRTVLELDRMEMSMDAFQKKFYEKDLLDQEKEREELLLLEMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQAFHAKYGNLEKCASKSSTTGYTTSVSGLGKTSVLSLADDSFRTRNASSVPSSFSPNTPLPSTSRGTGNSVDPKSSGSKDTQPRKATLKSRKSNP
The following text describes a protein:
Function:
Catalyzes the demethylation of N,N-dimethylglycine to sarcosine. Also has activity with sarcosine in vitro.
Subcellular Localization:
Mitochondrion.
Sequence:
MSAMLRAALRRLPLPCRGGRPGPSAALRALGGAASARAGKENRSPSLGKDKADTVIIGGGCVGVSLAYHLAKAGLQDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHAYSIKLYEKLEEETGQAVGFHQPGSIRIASTPTRVDEFKYQMTRAGWHPTEQYLITPEKVQELFPLLNMDKVLAGLYNPGDGHIDPYSLTMALAAGARKYGAQLNYPVQVTNLNSRSDGTWEVETPLGVIQAKRIVNTAGFWAHEIGKMIGLQHPVIPVHHQYVVTSTVPEVKALKTELPVIRDLEGSYYLRQERDGLLFGPYESQEKMKLQDSWVTNGVPPGFGKELFESDLDRIMEYVEAAMEMVPVLKKANIINTVSGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGIGKYLSDWILEGEPPFDLIELDPNRYGKWTTTEYTAAKARESYGFNNIIIYPKEERFAGRPTERTSGLYDLLKTKCSMGFHAGWEQPHWFYKPGDETGYKPSFRRTNWFDPVGREYKQVMERVGVIDLSPFGKFKVKGTDSVKLLDHLFANVVPKVGSTNISHMLTPKGKVYAELTVSQLYPGEFMLVTGSGSELHDLRWIEEEVVRGGYKVEIENMTDEMGVLGVAGPYARQVLQRLTAEDLSDGSFKFLQSRHLKLSDIAVTAIRISYTGELGWELYHRKEDSVALYNAIMDAGQKEGIDNFGTYALNALRLEKGFRAWGAEMNCDTNPLEAGLEYFVKLNKPADFIGKKMLKQIKEKGLKRRLVYLTLETDDVDPEGNESVWHNGKVIGNTTSGSFSYSAKQSLAFAYVPTELSKVGQKLEVELLGKNYSATIIQEPLVLTEPTRTRLQRKGQSPKI
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDSSAAASSSSSAGPLSVVHVAFPEVTGALLESLNQQRLEGKLCDIAIQVQGRVFRAHRAVLAASSPYFHDQVLLKNMTSVVLPSVMDPVAFEAVLGSAYTGHLSMAADEIVNFLTVGSVLQMWHIVDKCTELLKERRGALLLGSAAAPSSSLAPSSSSSSLAPSSKFILEMEDDEGSDGGEPGCSVPPGGSRRPPLHRPAYLRPSIVPQRQWVFVKKERPQEDLVLTCEEEDEDPVEEVELEEQVNFCESSEDFPSPYEGNHVVLFPAGSGPAAGASLAASTVEHGAVQLASGSGGDGNKIFMCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECDVCAKKFMWRDSFMRHKGHCERRHRLEPDGGQTWTFIMRDNRFFVWAPFSLS
The following text describes a protein:
Function:
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC/SPE1 monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.
Sequence:
MYEVIQKRKTKIINVLQSPELMRLIEDPSNLGISLHFPVSSLLKSNKCTPMPKLSTYSLASGGFKDWCADIPLDVPPEIDIIDFYWDVILCMESQFILDYNVPSKNKGNNQKSVAKLLKNKLVNDMKTTLKRLIYNENTKQYKNNNSHDGYNWRKLGSQYFILYLPLFTQELIWCKLNENYFHVVLPSLLNSRNVHDNHSTYINKDWLLALLELTSNLNQNFKFEYMKLRLYILRDDLINNGLDLLKNLNWVGGKLIKNEDREVLLNSTDLATDSISHLLGDENFVILEFEC
The following text describes a protein:
Function:
Catalyzes the attachment of glycine to tRNA(Gly).
Subcellular Localization:
Cytoplasm.
Sequence:
MVRMEDIISLAKRKGFVFQSSEVYGGLSGAWDYGPLGVELKKNIKKEWWKSMVYLHENIVGLDSAIFMRPEIWRASGHVDGFSDSMVDCKDCKSRFRADFIDLSKNCPNCKVGNNFTSPRSFNLMFKTHIGVVEDSSSEVYLRPETAQGIFVNFRNVLDSSRLKIPFGIAQVGKAFRNEIVTKNFIFRTCEFEQMEMQFFVHPKQIDEWFCYWQQNRMNFFIETLKISPDRLRFKAHDSTQLAHYAKAAFDIEYEFPFGFQEVEGIHNRGNYDLTQHAKFSNKPKVFEYHDLLTKEKYVPYVIETSAGLTRSVLMTLCDAYSEEELSDGDKRIVLRLHPKLAPYKIAIFPLVKKVELTEIARRIYMELCDDFHIFYDDSGTIGKRYRRQDEIGTPYCVTIDYNTIEDETVTVRERNNMTQKRIFINDLYSYIKTEILNYKEDFNK
The following text describes a protein:
Function:
Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.
Subcellular Localization:
Golgi apparatus.
Sequence:
MPGSSLWLIPPPSHPLYPILSFLISQHLPSDFPSEAGAADARLIPEFFAPHMTLSSGISPDLYGDDPQRWLDSIPWPSADEVQVRFEGISSQDTYYRRCYARVKLDEGIKKIAGLARARGVNGEDDAKGAKTQEWLEWWRKEFGPHVSLMYGDVPISDDRLKEVAKVVEEAGVKLAEPEGNVEGNGWNGGVVWLVPTDRDIRDWKPIAKRVL
The following text describes a protein:
Function:
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer (Probable). Required for septum formation (Probable).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTRNPFMVEPSNGSPNRRGASNLSKFYANANSNSRWANPSEESLEDSYDQSNVFQGLPASPSRAALRYSPDRRHRTQFYRDSAHNSPVAPNRYAANLQESPKRAGEAVIHLSEGSNLYPRDNADLPVDPYHLSPQQQPSNNLFGSGRLYSQSSKYTMSTTSTTAPSLAEADDEKEKYLTSTTSYDDQSTIFSADTFNETKFELNHPTRQQYVRRANSESKRRMVSDLPPPSKKKALLKLDNPIPKGLLDTLPRRNSPEFTEMRYTACTVEPDDFLREGYTLRFAEMNRECQIAICITMYNEDKYSLARTIHSIMKNVAHLCKREKSHVWGPNGWKKVSVILISDGRAKVNQGSLDYLAALGVYQEDMAKASVNGDPVKAHIFELTTQVSINADLDYVSKDIVPVQLVFCLKEENKKKINSHRWLFNAFCPVLQPTVVTLVDVGTRLNNTAIYRLWKVFDMDSNVAGAAGQIKTMKGKWGLKLFNPLVASQNFEYKISNILDKPLESVFGYISVLPGALSAYRYRALKNHEDGTGPLRSYFLGETQEGRDHDVFTANMYLAEDRILCWELVAKRDAKWVLKYVKEATGETDVPEDVSEFISQRRRWLNGAMFAAIYAQLHFYQIWKTKHSVVRKFFLHVEFLYQFIQMLFSWFSIANFVLTFYYLAGSMNLVIKHGEALFIFFKYLIFCDLASLFIISMGNRPQGAKHLFITSMVILSICATYSLICGFVFAFKSLASGTESHKIFVDIVISLLSTYGLYFFSSLMYLDPWHMFTSSIQYFLTLPAFTCTLQIFAFCNTHDVSWGTKGSTQESKQLSKAIVVQGPDGKQIVETDWPQEVDKKFLEIKSRLKEPEFEESSGNEKQSKNDYYRDIRTRIVMIWMLSNLILIMSIIQVFTPQDTDNGYLIFILWSVAALAAFRVVGSMAFLFMKYLRIIVSYRNKVEGSGSWEVSKLDLPNVFHKKG
The following text describes a protein:
Function:
Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum. Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3. By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis. Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens. This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MDLQQVYLAAVVLAALALTLADEEAKKLWDRLDHLDPNHDGVVTQEELKNFAFWERTKDLREDAAEQWDTLEVPPGEKLTFGHYKEKSYGEDFSEDDDLGPYGRTVQQDHARFNASDQNKDGALDKEEFLAFLWAEEYPHMHDIITLETMEDLDKNGDGAISFTEFAGDDEGVMEDSVDHMEFKESDKNQDGQLNHAEVKEWLLGPTLKEDDERVATVLSKLDKDEDGKLTRSEIEADPEVIETLMYEEDGGEYLHDEF
The following text describes a protein:
Function:
Mediates sugar transport across membranes.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MEALGDLLAPHSELIAKVAGTITTLQFLSGVVLMNDIRKKGSSDVYPVGPFLFGVVLTVLSLKLANIMNDAAMINTNLIGLVINFVFLFGFYYYASSASRSKIWKQIGYSSVFLLAITAYANFEDPAKIEFRLGMLITGILVWMVGSPLLHLPKIIEKKSTEGMPFPIIFAGNLVAFSWTLYAISIKNTVMVLQNLLLLVLGGIQLSMFAIYPNKPAAEKPKDSKKDK
The following text describes a protein:
Function:
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity). Required for primary neurogenesis and for anteroposterior neural patterning.
Subcellular Localization:
Nucleus.
Domain:
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain; The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
Sequence:
MSSKDNTCPPPGPGHINGFHVPHYAFFFPHMLGGMSXTGGLPGVQHQPPLSGYSTPSPATIETQSTSSEEIVPSPPTPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKESPKPEAIESYILSPETQDLIEKVQKAHQETFPALCQLGKYTTSFSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKSACLDILILRICTRYTPDQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQPVPLEMDDAETGLLSAICLICGDRQDLEQPDKVDKLQEPLLEALKIYVRTRRPQKPHMFPKMLMKITDLRTVSAKGAERVITLKMEIPGAMPLIQEMLENSEGLDTLGGGASSDAPVTPVAPGSCSPSLSPSSTHSSPSTHSP
The following text describes a protein:
Function:
Probable chloride channel.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEVIEVSGEDGGMYIENGDSFLIHFLHSFPRIDFSLTVVNSTFDLESTKYKESLLFWASLPVLGLLIVLISLLAYLIFRCICKSAYDDESTNRSRISESECEKTNKCISCVKWSISCLVLLACGSSAFGFYGNNEIRKGSNIVSDAIASTAINLYYAQTQVSQLRNLINSTNAEIKSLRETLKRHFGQYRHLNTTANEELGKHLELMSRRMTEVWNHVRDLVDRDEKRDETDSKVAIYSKLFEDFDLYRWITCISIFVWLIVLSLMLLLGAVKSSKCLLLVLILIGAIFKFTTFQILYMWYSNSCGLLVVMQLTSRINSSFTEYYIKCNPTKHPNPLVHHIKGAQNGVSEMNSNINEAANYIKNFLPQSEYTSGSICRQYSGLLNLSENCSTMRESIA
The following text describes a protein:
Function:
Involved in the fragmentation of the mitochondrial network (By similarity). Involved in perinuclear clustering of the mitochondrial network (By similarity). Plays a role in removal of ultraviolet C radiation-induced mitochondrial DNA damage. May act, redundantly with fis-2, downstream of mitochondrial fission, before the fission products participate in either mitochondrial homeostasis, mitophagy, or apoptosis.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.
Domain:
The C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission.
Sequence:
MEPESILDFHTEQEEILAARARSVSRENQISLAIVLVGSEDRREIKEGIEILEDVVSDTAHSEDSRVCVHYLALAHARLKNYDKSINLLNALLRTEPSNMQATELRRAVEKKMKREGLLGLGLLGGAVAVVGGLVIAGLAFRK
The following text describes a protein:
Function:
Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Required for the processing of 21 nucleotide trans-acting siRNAs (ta-siRNAs) derived from TAS3a transcripts. Associates preferentially with the microRNA (miRNA) miR390 which guides the cleavage of TAS3 precursor RNA. Seems to act as miR390 specific slicer. Associates mainly with small RNAs of 21 nucleotide in length and with a 5' terminal adenosine. Acts in the RDR6/SGS3/DCL4/AGO7 trans-acting siRNA pathway involved in leaf developmental timing. Does not seem to act on leaf polarity. Required for the production of the 30-40nt bacterial-induced long siRNAs (lsiRNA). Involved in antiviral RNA silencing by contributing to efficient viral RNAs clearance. Targets less structured viral RNAs than AGO1 which is capable of targeting RNAs with more compact structures.
Sequence:
MEEKTHHHHHSTNKHIPSSKSRTPLLHKPYHHHVQTNPPPFLLHPSSHQNLNLVASNLPSSYYYYYYCYFYSQFHNSLPPPPPPHLLPLSPPLPPLLPLPPPHSMTRFHKSLPVSQVVERKQQHQQKKKIQVSNNKVSGSIAIEEAALVVAKRPDFGGQDGSVIYLLANHFLVKFDSSQRIYHYNVEISPQPSKEIARMIKQKLVETDRNSFSGVVPAFDGRQNIYSPVEFQGDRLEFFVNLPIPSCKAVMNYGDLREKQPQKKIEKLFRVNMKLVSKFDGKEQRKEGEDWAPLPPEYIHALDVILRENPMEKCTSIGRSFYSSSMGGSKEIGGGAVGLRGFFQSLRHTQQGLALNMDLSITAFHESIGVIAYLQKRLEFLTDLPRNKGRELSLEEKREVEKALKNIRVFVCHRETVQRYRVYGLTEEITENIWFPDREGKYLRLMSYFKDHYGYEIQFKNLPCLQISRARPCYLPMELCMICEGQKFLGKLSDDQAAKIMKMGCQKPNERKAIIDKVMTGSVGPSSGNQTREFNLEVSREMTLLKGRILQPPKLKLDRPRNLKESKVFKGTRIERWALMSIGGSSDQKSTIPKFINELTQKCEHLGVFLSKNTLSSTFFEPSHILNNISLLESKLKEIQRAASNNLQLIICVMEKKHKGYGDLKRISETRIGVVTQCCLYPNITKLSSQFVSNLALKINAKIGGSMTELYNSIPSHIPRLLRPDEPVIFMGADVTHPHPFDDCSPSVAAVVGSINWPEANRYVSRMRSQTHRQEIIQDLDLMVKELLDDFYKAVKKLPNRIIFFRDGVSETQFKKVLQEELQSIKTACSKFQDYNPSITFAVVQKRHHTRLFRCDPDHENIPPGTVVDTVITHPKEFDFYLCSHLGVKGTSRPTHYHILWDENEFTSDELQRLVYNLCYTFVRCTKPISIVPPAYYAHLAAYRGRLYIERSSESNGGSMNPSSVSRVGPPKTIPLPKLSDNVKNLMFYC
The following text describes a protein:
Function:
Golgi-resident glycosylphosphatidylinositol (GPI)-N-acetylgalactosamine transferase that catalyzes the N-acetyl-beta-D-galactosamine transfer from an UDP-N-acetyl-alpha-D-galactosamine to the 4-OH-position of first mannose of the glycosylphosphatidylinositol (GPI) of a GPI-anchored protein (GPI-AP). This modification occurs after the fatty acid remodeling step of the GPI-anchor maturation.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Domain:
Contains three transmembrane domains, including a tandem transmembrane domain insertion into its glycosyltransferase-A fold. Transmembrane domain 1 functions as a signal for Golgi targeting; The conserved DXD motif is involved in enzyme activity.
Sequence:
MSTSTSPAAMLLRRLRRLSWGSTAVQLFILTVVTFGLLAPLACHRLLHSYFYLRHWHLNQMSQEFLQQSLKEGEAALHYFEELPSANGSVPIVWQATPRPWLVITIITVDRQPGFHYVLQVVSQFHRLLQQCGPQCEGHQLFLCNVERSVSHFDAKLLSKYVPVANRYEGTEDDYGDDPSTNSFEKEKQDYVYCLESSLQTYNPDYVLMVEDDAVPEEQIFPVLEHLLRARFSEPHLRDALYLKLYHPERLQHYTNPEPMRILEWVGVGMLLGPLLTWIYMRFASRPGFSWPVMLFFSLYSMGLVELVGRHYFLELRRLSPSLYSVVPASQCCTPAMLFPAPAARRTLTYLSQVYCHKGFGKDMALYSLLRAKGERAYVVEPNLVKHIGLFSSLRYNFHPSLL
The following text describes a protein:
Function:
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death (By similarity). Plays an important role during the formation of the nexine layer of the pollen wall.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MARQFVVLVLLTLTIATAFAADAPSASPKKSPSPTAAPTKAPTATTKAPSAPTKAPAAAPKSSSASSPKASSPAAEGPVPEDDYSASSPSDSAEAPTVSSPPAPTPDSTSAADGPSDGPTAESPKSGAVTTAKFSVVGTVATVGFFFFSF
The following text describes a protein:
Function:
Cytokine that acts as a physiological ligand for receptor tyrosine kinase LTK, leading to its activation. Monomeric ALKAL1 binds to LTK, leading to LTK homodimerization and activation. In contrast to ALKAL2, does not act as a potent physiological ligand for ALK.
Subcellular Localization:
Secreted. Cell membrane. Note=Following interaction with receptor tyrosine kinase LTK, associates with the cell membrane, membrane-binding is required to activate LTK.
Sequence:
MRPLKPGAPLPALFLLALALSPHGAHGRPRGRRGARVTDKEPKPLLFLPAAGAGRTPSGSRSAEIFPRDSNLKDKFIKHFTGPVTFSPECSKHFHRLYYNTRECSTPAYYKRCARLLTRLAVSPLCSQT
The following text describes a protein:
Function:
Produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Sequence:
MVMDIRVLTPDRVICSTTADEVILPGLTGQVGVLDGHATLITALDTGLLRIKLADKWTPIILCGGLAEIDRNRVTVLVNDVEELVAVELSEATKELEKATSAIENAETSKARLDASVELKKATARLEGINYLS
The following text describes a protein:
Function:
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Has been shown to bind to the direct repeat sequence 5'-GTT-N(7)-GTTC-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Sequence:
MLTRKQMELLDFIKTRMDRDGVPPSFDEMKDALDLRSKSGIHRLITALEERGFIRRLAHRARAIEIVKLPEAMERAGFSARAAKAAAAPLPKGAVTVETAGALDLPLMGRIAAGLPIEAINGGPQSVTVPGMMLSGRGQHYALEVKGDSMIAAGINDGDIVVIREQQTADNGDIVVALVADHEATLKRYRRRGGMIALEPANDSYETQVYPEQMVKVQGRLVGLIRSY
The following text describes a protein:
Function:
MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MDLSTILGLVLAVASISLGDILEDGNPLHIIHLSSVIIIVPTSLFAAMTGTHARYVKAAYKEIKIVFLNPKINLNETIKNLVELATLARKDGVLSLEGRVAQIEDDFTRNGLSMIIDGKDLKSVKESLEISIEEMEEYYHGAAHYWETAGETAPTMGLVGAVMGLMLALQKLDNPAEMAAGIAGAFTATVTGIMCSYAIFGPFGHKLKAKSKDIIKEKTVLLEGILGIANGENPRDLENKLLNYIAPGEPKKSQFEG