lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Ribosome-binding protein involved in ribosome hibernation by associating with translationally inactive ribosomes. Required for translational recovery after starvation from stationary phase. May facilitate rapid translation reactivation by stabilizing the recycling-competent state of inactive ribosomes.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGNPKKRAEKAEAAKSRKQDEEKKKKDAEEDEKWSKGVKTNKKEQEAEKRKAALERKAERERLEKEEMESLPSKGGKGSKKAAKKNSSLDAFLNETPQTASYSARNIDDALDLLSLNNSSSKDKIDRHPERRFKAALTEYKQSRLPELRKEQPGLRLNQYEDIMYKEFQKHPDNPFNKMNVSYNTSQDEVEQLRKARKAELEARLRE
The following text describes a protein:
Function:
Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
Sequence:
MTHATSATSDMVAAALDRALTDHEDDIDSDARDRILTEATRNAYDDATTDERYDALLGALTGRIDRHPAYKTVAGRVLRERLERRLVDDYDPATRDAATRQAFRDGIQRGLDADLLDERMGDYDLNRLADAITPARDDRLDYMAMDTLRQRYFLREPDADPFELPQPFWMRVAMGVALREDPADREEYAIEFYDALSTLRFVHSTPTLFHAGTTHAQLSSCYLTTVPDDLDGIFDAYKEHAKLSKWSGGLGNDWTPLRAAGSLIESTGVESTGTVPFLKISNDVTAAINRSGKRRGAAAAYLACWHLDFPAFCDLRRNTGDERRRTHDMNTAAWIPDLFMERVRADKQWTLFSPKETGDLYELYGSDFAERYREYEAMADDGDIQRFERVDATDLWRTMLTRLFETGHPWLTFKDPCNVRSPQDHAGTVRSSNLCTEITLNTSEEETAVCNLGSVNLARHLDDGDIDREQLSETVETAMRMLDNVVDLNFYPTENAERSNMRHRPVGLGVMGFHDALQQMRVPMASDDALDRADALQEYVAYHAIGASADLAAERGTYESYEGSKWDRDVFPQDTVDRLESERGREIPVPREERLDWSDVRQRVATHGMRNSNTMAVAPTATISTIAGTTPSIEPVYSNLYVKSNMSGDFTVVNDRLVADLEERDLWTEELRDKLTYHDGSVQELDAVPEDVQELYRTAFEIDPRHQLRLAARRGVWIDQSQSVNVFFPETDGSKLSEVYQTAWELGLKTTYYLRTLGASQIEKTTLDMDEYDDTQFRGDDDGEDADGDGDLPSVEDPTCEVCQ
The following text describes a protein:
Function:
Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
Subcellular Localization:
Endomembrane system; Single-pass type IV membrane protein.
Sequence:
MDTQLKATREEIDNVQLLLIAIERQTGNHEVDRLIQDANSSLMKTETHMFRLESQLGREPAPVRQKASFKMDQLKSDVCLIKNSLRTMTNRHTNRKKQAEEKKALLKQRFTTNQETRVNLEFDEELNLNDKLKYSDNMIDQMLAQGASVFEDLQKQKYNLLSIRKRFHFLTKSLGISDTTIRLIEKRVREDKKLFMIGVICCLIFMFCFYYWWQYC
The following text describes a protein:
Function:
Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
Subcellular Localization:
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Sequence:
MTDLVYEQPLNEKIRSYLRLEYLSKQLCNNLNNDHQHRCFYPLFSLCELSERCDYRNEVLKDIERNLLQLSKWQELEHIDSKQITFYIEALTQARESLQRPERCGNQLKQDRFLSALRQRFGMPGACCNFDLPQLHFWLAKPWDERRQDYQAWVSHFEPLLTPIALLLQLTRSTADYAKATAHAGFYQGDSTQALSLVRVKVDAAHGCYPTISGHKNRFAIHFVQFDQQRHSDRSIEFLLATCA
The following text describes a protein:
Function:
Transcription factor binding to specific DNA sequences of target genes promoters, such as the motif R1BS 5'-NAKATNCN-3' and the motif P1BS 5'-GNATATNC-3' to trigger their expression. Nitrate-induced component involved in modulating phosphate (Pi) response and homeostasis together with PHR2; activates directly the expression of Pi starvation-induced (PSI) genes upon nitrate disponibility, thus triggering the nitrate-induced phosphate response (NIPR) promoting Pi uptake activity; [Isoform RLI1b]: Binds preferentially to the P1BS motif 5'-GNATATNC-3' in target genes promoters; [Isoform RLI1a]: Binds preferentially to the R1BS motif 5'-NAKATNCN-3' in target genes promoters, including several genes involved in the plant hormone signal transduction pathway. Involved in the shoot architecture; positively regulates leaf inclination by affecting lamina joint cell elongation via the direct promotion of ILI4/BU1 and BC1 genes expression, especially in response to phosphate (Pi) availability. Regulates both brassinolide (BL) biosynthesis and signaling by directly activating BL-biosynthesis and signaling genes.
Subcellular Localization:
Nucleus.
Sequence:
MLQDIMNTKKIKLHDCHFGSPLCDPSPAPHLLSSAAAAGLSFHPGLVSSAAQHQQHGAGGWLHEEYYAPRSSPPSSLLAQTCVGSNATAFYAAENLPQFDFPALGTAAAAAAKAPFRSSESELYRPVDPLLLRADHSVRTYYVRPQKRDSGERTPLPPPSQQQHQDRIHGLFAGAPTTRLLSGEPKIHSFPPQVAAKPILPAMDAPSLQNQMENQLTRNCIGAATPVTPTGNLAGSGAPSKTRIRWTQDLHERFVDCVNQLGGADKATPKGILKLMNSDGLTIYHIKSHLQKYRIAKYMPASSEGKQLEKRATGNDMQNLDPKTGMQITEALRVQLDVQRRLHEQLEIQRNLQLRIEEQGKRLQKMFEDQLKASRSVMEPQELDDVVAFAAGDGDDDAFDDVDVQLLAVAGSGYDDAGFQSKIS
The following text describes a protein:
Function:
Catalyzes the conversion of 7,8-dihydroneopterin into 6-hydroxymethyl-7,8-dihydropterin, a biosynthetic precursor of the vitamin tetrahydrofolate. Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin.
Sequence:
MHSSLETTAPATLERRESNLGDKLILKGLKFYGFHGAIAEERTLGQMFLVDIDAWVSLKKAGESDNLEDTISYVDIFSLAKEIVEGSPRNLLETVAELIASKTLEKFHQINAVRVKLSKPNVALIKSTIDYLGVDIFRQRNTSSKN
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MSSYVANSFYKQSSNIPAYNAQTYGNYGSVADAPSSRYCYGRLDLSLTFPAPAPSGSAHGLDMATTARPAPERPACTAAHHCPGDPAPLGAGMYRRKVDSPPLEEPAPSSGGIKEEQSPALQAGGTPQPPTQPQIYPWMTKLHISHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKLKSKDSL
The following text describes a protein:
Function:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Sequence:
MDLQEHHDLIFGEEFCFPAATTYYPPLYVPTGINVVPAQLYQHQANSRCDNRAQTYMGHEVQGTPSMYYVVPNYGIAHSPHGPHPLHPCAIGDGRFVRTQEYYSETVEHTYQQPVPTSYCSIRPSAADRTPASTAQSLGYTNDLFVPGGLRQTVSVTSERGVAWNQSLQQATIASMEFQSHTSLPERGVTWNQSLQQATISSMEFQSHASLQKELPHTPPPWKRQLSGGVRASARLPRARRAPHPSPQVAVRSSLHTNLSYNNRVSNVGSDLCEMQSTEITQPYERTSSCANQRVSPMSQQNTSKAKMPIGSMPPEIIVKSYTSRLLVGNPDGKIVIRSDQYNRHDFPVVYPNAKFFVMKSYDEADIHKSIKYGVWSTSSVGNQKLDIAFREAQAISASSCTLCPVFLFFSVNESFHFCGVAEMVGPIDYQNDMDFWCMDKWTGSFPVKWHIIKNVHNSTFRSILLQNNEDKPVTSSRDTQEIHYTPGTTMLELFKYTRADGCVLDSFMLHEEKEASSRQLQKFKLRRGAPHFIPAWHGPRPYRHVLPKSDSVVMGKITTDFETSNLANKLQNLNLEKNQASWQDFRHLTSIASTKKRQKDCYPYGTRAHGRRNKDIVKAYHPMAPNKKSALDEEHRYWKKKPQPGTVASVSSKAPPEEHQQGVKNTDAHSALVAPEMTCEEQKIVGKACPPAVVSTTSKACSELLPGVVAIGSMLIPITMPN
The following text describes a protein:
Function:
Binds to actin and is involved in actin-ring formation and organization. Plays a role in cytokinesis and is involved in septation.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Localizes to the medial ring in an F-actin-dependent manner.
Sequence:
MQANQWQSVQNRTFTKWFNTKLSSRDLPSVFDLRKDLSDGILLIQLLEIIGDENLGRYNRNPRMRVHRLENVNKALEYIKSKGMPLTNIGPADIVDGNLKLILGLIWTLILRFTIADINEEGLTAKEGLLLWCQRKTANYHPEVDVQDFTRSWTNGLAFCALIHQHRPDLLDYNKLDKKNHRANMQLAFDIAQKSIGIPRLIEVEDVCDVDRPDERSIMTYVAEYFHAFSTLDKVETAARRVERFTEVLMSTHDMKIDYESRMKRLLGSIARMQEYWHTVQFENNYTDVKSHSNNFAKFKATEKREWVKEKIDLESLLGTIQTNLKTYQLRKYEPPAGLKIVDLERQWKDFLSEEANQSKLINTHMREIKESMRIAFADRANSFSKMLSTISNEITNLQGDWRDQLDHVEFLQEHLGPLEVELASVKVLYDNCFQAGIEENDYTMFSYEDLEHEFGITANIIANKIKYLENELLEREKRTLSKQELDGITKVFRHFEKKKSNMLNEVEFYAALASLGLVYDTEEGTALFHRAANSEEGVTYERFTEIVMEELEDRDSARQVLYAFCDVADGKSYVTSDDLLRSQVRPNIVKFLECNMNKHSEGLDYLTWIKQLLAEDKEIV
The following text describes a protein:
Function:
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from the precursors of K1, K2 and K28 killer toxins and a-factor (mating pheromone). Involved in the programmed cell death caused by defective N-glycosylation and also contributes to the active cell death program induced by acetic acid stress or during chronological aging. Promotes cell fusion by proteolytically processing substrates that act in parallel to PRM1 as an alternative fusion machine, as cell wall components, or both.
Miscellaneous:
MISCELLANEOUS: Present with 8550 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Sequence:
MFYNRWLGTWLAMSALIRISVSLPSSEEYKVAYELLPGLSEVPDPSNIPQMHAGHIPLRSEDADEQDSSDLEYFFWKFTNNDSNGNVDRPLIIWLNGGPGCSSMDGALVESGPFRVNSDGKLYLNEGSWISKGDLLFIDQPTGTGFSVEQNKDEGKIDKNKFDEDLEDVTKHFMDFLENYFKIFPEDLTRKIILSGESYAGQYIPFFANAILNHNKFSKIDGDTYDLKALLIGNGWIDPNTQSLSYLPFAMEKKLIDESNPNFKHLTNAHENCQNLINSASTDEAAHFSYQECENILNLLLSYTRESSQKGTADCLNMYNFNLKDSYPSCGMNWPKDISFVSKFFSTPGVIDSLHLDSDKIDHWKECTNSVGTKLSNPISKPSIHLLPGLLESGIEIVLFNGDKDLICNNKGVLDTIDNLKWGGIKGFSDDAVSFDWIHKSKSTDDSEEFSGYVKYDRNLTFVSVYNASHMVPFDKSLVSRGIVDIYSNDVMIIDNNGKNVMITTDDDSDQDATTESGDKPKENLEEEEQEAQNEEGKEKEGNKDKDGDDDNDNDDDDEDDHNSEGDDDDDDDDDEDDNNEKQSNQGLEDSRHKSSEYEQEEEEVEEFAEEISMYKHKAVVVTIVTFLIVVLGVYAYDRRVRRKARHTILVDPNNRQHDSPNKTVSWADDLESGLGAEDDLEQDEQLEGGAPISSTSNKAGSKLKTKKKKKYTSLPNTEIDESFEMTDF
The following text describes a protein:
Function:
Probable amino acid transporter of unknown specificity.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MSELGEYSKLENKELRTEFELTNFPFPGTTDNDSDDGSQGQNSLNIITPDMDDTLVNDVLRENDKKSSMRMAFMNLANSILGAGIITQPFAIKNAGILGGLLSYVALGFIVDWTLRLIVINLTLAGKRTYQGTVEHVMGKKGKLLILFTNGLFAFGGCIGYCIIIGDTIPHVLRAIFSQNDGNVHFWLRRNVIIVMVTTFISFPLSMKRNIEALSKASFLAVISMIIIVLTVVIRGPMLPYDWKGHSLKLSDFFMKATIFRSLSVISFALVCHHNTSFIFFSMRNRSVAKFTRLTHISIIISVICCALMGYSGFAVFKEKTKGNVLNSFPGTDTAINIARLCFGFNMLTTFPMEIFVLRDVVGNLLHECNLIKNYDEHTQLSGKQHVVITSSLVFITMGISLTTCNLGALFELIGATTASTMAYILPPYTNLLLTSKKKSWKERLPFYLCICFGFMIMIISSTQTIIDAVNGSDGQHCQI
The following text describes a protein:
Function:
Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Binds RNAs which might negatively affect its histone methyltransferase activity. COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face.
Subcellular Localization:
Nucleus. Chromosome.
Domain:
The RxxxRR motif forms an adapter helix that bridges the nucleosome and ubiquitin.
Sequence:
MSYNPYRSRNYGGGYSNNGYRQRHYYSDYNESSYNSSYRDQYDRNGSYSGSKGRHYNSGTSRNAPPPSSSAYSSDSSSRTYANSSSSGPAKIPVGPKSLTIDGSTNGDLPTAGTQKHNIPPTNAISGTDATTGVNPNDSNFTQLLLHQDLSKQIEFSGEIDSKRNYKVIYDPELDKSLSKAERKTKQKKIRFNGESLSSHDVTDPRKSSTGSTSAYFLKPNKKSKKFPFKQLPQPKFIYDKDSLGPPPQNEIVVWDLPSTTSEVYLSNFFKSYGDSIKDLKFINDPLNAVPLGIATCKFQGNPDKSMRIAKKFIANVRINHTKIDGAELKIALNDNDNKLLDDKIKVAQDKLRISRIKIEEEEKKRLKKQQAIEDQKRRETEKAAKEKKLQESANSSHESRFKPNTTTLSIRHHNEVIPGVFLPRELRKYIRDRPYIFINDKYVPTRKVSSQDIKKVLNKYDWTRVLPDRSGFFVVFNSIKECERCFINEDGRKFFEYKMFMELALPENFNESSSSTSNNDNTDLSASNRKQNDVVEEASNMLIKEFQNFLAKDIRERVIAPVVLDLLSHDKYPKLVEELKAKELATKKAASPIVTNAVRQVKSKPNVLSSLAIKSKPQAILPSFRKKKDLPNAGLNSANKAKKNVIPMQHALNYDHESDESDEDDSTRSTTPLTPTLKRERSPTVSSVSNDNDIEDKLEDIQKPSKKKQKKTKLHQSFLYDSASDEDMEAVSEEKEVEKDESEGEEDIDYSHIDKIYQPTEDYPRPVYEEVPRFPSDPLDLDALQSIIKDDEDITLLQTALADVTSESNIKNMEYWAWKQKDIKAKAGVQEISEDLEVIGPLDSRFDSKSGAFKSEGYRKIPDADKIEYLPHRRKIHKPIKTIQHDDDELNANNSTTNNNSNNIQSSRVNRANNRRFAADISAQKQMLGSETDILNLNALTKRKKPVSFARSAIHNWGLYALEPIAAKEMIIEYVGESIRQQVAEHRERSYLKTGIGSSYLFRIDENTVVDATKKGGIARFINHCCNPSCTAKIIKVEGKKRIVIYALRDIEANEELTYDYKFEKETNDAERIRCLCGAPGCKGYLN
The following text describes a protein:
Function:
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine. Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate. Also has adenosine deaminase activity.
Sequence:
MYKQDFPEGKEALNLEIRLGNKLVRFRKFTGKEKIYLPIQRHTDKVIKLIDKDSPPLEGDAVITNLKNVEIGVRTADCVPIILLGKEWVGAVHAGWRGLKKGIIAKTLKALKEEGEDDITALVFPSAKGCCYEVGKEFKEFFRRNLKERNGKLFFDPQREAVEQLRENGIKSILVWEKCTICSPELPSYRRDKTKERMLTSVVILF
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MKGAKLSEPTLSFLRDNMKFTTMAPVQARTIPLFLTNYDVVVEAITGSGKTLAYLIPCLEMLLRPRCREVAKEYKNAVFAVLVLPSRELAQQVFQIVKRMLHFVTKGYKNGSPANGLPAYSYQCYIGGRDIKHDVEEFSKQGGNVLVGTPGRLYELLVSSKYANLFHLSQFELLILDEADKLLEFGFRAKLDALLKRLPRQRRTGLFSATQTKELAELARAGMRNPVSVTVRINPLNAPDSDTAKPQIPEQLSNFFAFTRASEKLDRLVEFLASHRGEKVLVYVMTCASVEWLYEALSAVLLKDEADSVFALHGQMKLEKRQQVHRQVTRRSRCVLVCTDVAARGLDIPEVGVVVQYDPPVDPNTFIHRIGRTARMGRSGKSVVFLMPQELEYINFMRLQNVPLQSLDGEQDSVDVAKDAVRNMNARRTLLSSELPDKRKAIHQAHREKQLSRRERRQQLHEAHQAMVEGKSQRLAKRKEVLGDMCTSPSILALRREGCRNAKLLSLAARAFVSFLRAYKEHECRYIFQLQLIDLTDLTHGFALFKIPNCGEIKRMRVLRIPLQDEFAPFVRQMVTELREKRQRAAEEQSAMAALDGGSDDGPGAKRHRTERNEKLETLKLLKMSKSERSRAWKQAELDELLKDSYYVKMERRGKVNRHVVDEKMGVEAIENSFMSARERKEAQLARKAR
The following text describes a protein:
Function:
Transcription factor required for the maintenance of pluripotency and self-renewal of embryonic stem cells.
Subcellular Localization:
Nucleus.
Sequence:
MSAHLAMPSYGSVRCGHYYWPSPGSMDSASAAEAPAADLSLTTEQKTPCHPDASPASSSSGTLIQYTPDSATSPTADHPSHRPTFQKVKDKGESGTRKAKSRTAFSQEQLQTLHQRFQSQKYLSPHQIRELAAALGLTYKQVKTWFQNQRMKFKRCQKESQWVDKGIYLPQNGFHQAAYLDMTPTFHQGFPVVTNRNLQAVTSAHQAYSSGQTYGNGQGLYPFMAVEDEGFFGKGGTSCNTQQAMGLLSQQMNFYHGYSTNVDYDSLQAEDTYSFQSTSDSITQFSSSPVRHQYQAPWHTLGTQNGYET
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MANLSLYAVEAVVILDNDGQRIYAKYFNPPHQAVEEDSLSSNVKLQKELEATLFKRTHKQNADILILDEHLVLYKECADVCIYLLGPLDENEIVLQDTLGAMKLALEMVLNTDLDKRSLQDNYEIVCLVVDETVDDGIILETEARTIASRVTKSPTQETVVIDLSEKGLLSAWGFAKSKLAERLQQGL
The following text describes a protein:
Function:
Endoribonuclease that cleaves single-stranded RNAs; unlike its paralog EndoU it does not appear to preferentially cleave at uridylates and releases linear products instead of products that have 2'-3'-cyclic phosphate termini. Preferentially cleaves single stranded RNA at sites with AU, UC and poly-U sites cleaved less efficiently. Targets mRNAs encoding proteins involved in lipid metabolism, particularly those involved in lipolysis, to regulate their expression.
Subcellular Localization:
Endoplasmic reticulum lumen. Secreted.
Domain:
The signal peptide is not required for the protein's role in lipid droplet maturation; The EndoU domain is essential for the protein's role in lipid droplet maturation.
Sequence:
MRCLALSAVFLCLTLAGHFHLSDAYKNEVQITPDPLDAVETTTKKSSWFGGFKKFFGSDGTTTTTSTIAPPVVTSPKSVVVTPTAANKPPPLVISHAPLMPLGPRPDTPGSSPFGASQNPQTPPQWPSSTRATPSHPSQPSQPSQQPPLPGFASYRPQKPQPNSYDLSYGGGPQPAPAGTGRPGFGLGISSTTSTTTTAKPITSTTGKTPQQKEDFPALPGPRRPSQKEDFPALPAPKTPPGSPTPTPGSPSAWQSPLPTPQHPVHPPTKATSAATPTPTPTPSFSSSVTPTPAHGSSVGPHKDGGGGGGGGTTTVRPGFQSSGNSVATDDEIRQLTELLYTKESNSQIGNIQVNLQGRTRSIDSADEAPNPLLTVDSKALESPTIVKMRLLFNNYEHDTHVNEHVTPNERKEENDFLDAVMATPVMRQAMLFLQQKGVVSPDPKTHRDLVKELWFTQYSRGQGKIGSSGFEHVFVYEVKDGTIIGFHNWVYIGDEEKDGRFDYKGYMKEQDIGTKGKIVKIRFSHQGLNKPVNTVFVGTSPELELALYTVCFQLRPDRTCPVSLGNSKFGIVTYSWRYRGKNLIGSAYPEI
The following text describes a protein:
Function:
In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.
Sequence:
MSLGIDMNVKESVLCIRLTGELDHHTAETLKQKVTQSLEKDDIRHIVLNLEDLSFMDSSGLGVILGRYKQIKQIGGEMVVCAISPAVKRLFDMSGLFKIIRFEQSEQQALLTLGVAS
The following text describes a protein:
Function:
Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.
Sequence:
MAHSAPPSYTGESVRSSICRLYGQRSDLPLTVLHATVPPVAASLVQQRSHVLDAIFDCIHDQLYPKDSAVGENADTRSSAITNHWLRSVPESLLFDEAAVVNYLGMVVAIDFCHWAEVPCKAGRTATASVGEEVTGFAGFYAAVDPPSGASAVGNGGTTASAAVAELFAEPPSAVGKELGTLSTAAAAAPTLLRGSAAMMYLLRRAVEVHRLPWFCPDFLQRFRGDTAAATSALRVCFLGCEQDGVTPLWMPCTRERVELLLSLADAFVARQTSYYKLLRACGGLLFAPDAAAAATAPCGFVPTLVRLHRRYADFARVPVEGPGCTGGNTGEAAPDVCIVPVLKLSQLTALAIEQALPVLWRYQAASSVSSKSLHSKLPPSAPANCWLTDRAARIARSGAESRTAEPESSLSGVFTDSAKLSICCDYQIPKALRAAGLLVYDDHLARIVDRHVLLMPGSAEEVSIRVATLIAAERLLQFLNTPPQRQSSLARELDATAAGVPGAPAQLPAKRLCSGIHLDYALWYVGRYMLPSEARHHLCRTIMY
The following text describes a protein:
Function:
Required for chloroplast biogenesis.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MEIFSASASLTLTGFVPRLLPLLSPQARTTLCKPLLSSSSTRLISCHSRIAPSRSLADQSASTGISVVDSDPIDVVKRKAMDIAPELKGASIFLVGINNSIKTNTGKLLAEALRYYYFDSDNLITEAAGGNVSAQALKEADEKAFQESETEVLKQLSSMGRLVVCAGDGAVQSLRNLALLRHGISIWIDVPLDITAKGDDDSFHSEPSPELFDTLKASYEKSRKGYETADVSISLEKIATKLEFEDLEAVTSEDIALEILKEIEKLTRVKKMMEEASRPF
The following text describes a protein:
Function:
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Localization:
Cytoplasm.
Domain:
The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
Sequence:
MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFTSSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPPQDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLAVAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMASGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPIPDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKLRPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSPKLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVTSNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNPNVFSEDEDDLPVTGASGVPENSPPCTVNIPIAPIHSSAQAMSPTQSIGLVQSLLANQNVQLDVLTNQTTAVGTAEHAGDSATQYPVSNRYSNPGQVIFGSVEMGRIIQNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSPPPADLQSHLGTEVMVETADNFQEVLSLTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKEARTLSDFNSLISSPHLGREKKKVKSQKDQLKSKKLNKTNEFQDSSESEPELFISGDELMNQSQGSRKGWKSKRSPRAAGELEEAKCRRASEKEDGRLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQVMQFGRIDGSAYILDFQYPFSAVQAFAVALANVTQRLK
The following text describes a protein:
Function:
Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
Subcellular Localization:
Lysosome.
Sequence:
MGLEQGWGTRWKSHDRSQTFSLNGRWEIRNSNGSYKLKGEVPGCVHTALAERLLIEDPYIRFNDAVYKWVAQDDWIYSRSFSLPPDIRFWQKVILVFEGLDTVSTILLNNFSVAKTYNMFTRYTVDVTNIVTKDNYIEVRFQSAVNWAKERSGNSSYKVPPDCPPPVQKGECHVNFIRKSQCSFSWDWGPSFPTQGIWKEVTIEAYNVFHLDYLSFVPVFDDKTSQWTVLLESVLDVITNGPLPGNVTVKIPDLNVDEMQKFVLIPGQQELKMAVKISKNIKVNLWWPNGYGSQNSYTITVKYLFEGGSTAENTTKIYFRSVELVEEPVPGSPGLSFYMKINQVPIFLKGSNWIPADSFQDKITLDRLHNLLQSVVDANMNTLRVWGGGVYESDEFYRLCDELGIMVWQDFMFACALYPTDIWFLETVEAEVIHQMRRLRSHPSIIVWSGNNENEAAIADNWFSVPAASQEVYRMDYVTLYIKTIMPLVLKMDETRPFISSSPTNGKESVQENWLAKNPYDNHYGDTHYYDYMTDCWDWKSYPKPRLASEYGFQSWPSLSTLEKVSDPVDWHYTSNFSSHRQHHSSGNEQMLSQAKLHYKNPENNDPIKEFQYTLYLTQVMQAQCVKLQTEFYRRSMREVVAGLGHTMGALYWQLNDIWQAPSWSSIEYGGKWKMLHYFAKDFFAPVAVSAFEDKDVLHIYGVSDLTKTISLQLEIKVYRWNSQVPVCEQLTEELLFNVNTSQIYTEPIPELLRRCQNSTRENSVVVFSLINQGQPYSSRNWHYLSSLKDAQGLLQPNITVSITQENTGFAFYLVTSAVAPFVWLDVWDIRGRFSDNGFLLADKTKTVYFYPWQTTSVDELQKSLNVTTLRDIY
The following text describes a protein:
Function:
Essential lysosomal hydrolase responsible for the degradation of glycosaminoglycans (GAG) such as heparan sulfate (Probable). Required for lysosome function and autophagy. Consequently, has an essential role in the development, maintenance and function of various cells, tissues, and organs, including the muscles and the central nervous system (CNS).
Subcellular Localization:
Lysosome.
Sequence:
MLSLLLVLTTLARIHAHYTSGDVVYHTMPHFWTGVGFCPAGRIDHEGISAALGDPALRLNLRLIAALPVGAVTHIRIHWLLELIQFWQYDPSGIPIYDFSKFDDFIDFLHEELRLSPVLEWMGNLGGVFSENPMQQSFYWEHLVKTTINHQIARHGSSRLVNWRYETWNEPDLRGYNKQNFTAHTFLDYVQAVRRGLSKAGNLDNQDGKVPLPMYRSLRGPAGLFKDSNHPLCWNLLELCSQRVVYCPIDILTFHRKGIEGTATEIVNGSLSLMAKIYEEYPNLKQLPVANDEADPVAGWSTSRDFQADVRYGITLISTVMQFWHAKLAGGPLSRLESISHDNAFLSYHPHEFTQRTLLAHFRMNETKPPHSQLVQKPVYAALGMLAKLGTRAADVEMVNMDTKHSVQVLRTVSGGLGGPGQYMATIFLSPEEAGPKMTAFHHKYTLNMSIANESAFVTELLVPKETDPYYIWQQAGSPAYPNATLREAMRRAQAPRLYKTGPIWQYNSELVINSASIPLPWAMLLRVCSASWPKLRRPQQLSIAEVTQREVFISWMEHPKSTQCLLSYEVWFKERDNLGRSADWMLISQGWHLPYPSFQYAPGDKGSVNGFYKVRGVDVFNETSPYSQIVEYLEL
The following text describes a protein:
Function:
Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
Subcellular Localization:
Membrane.
Sequence:
MSKDLTQSGTAGAGGSSLSSELFHAGVYKANQGRIVRQLTALAVWVIVALGCWRLYSFLPSAMGESSLAARAIPAALLAAGLWFGFRVVNWPRFADFLIAVEAEMNKVTWPSKDELIRASVVVIFTIFFLAITLFLFDVLWQFIFNFIGVTS
The following text describes a protein:
Function:
May operate as a cation/H(+) antiporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MENITKTYNYGGVDWICETWIGASSMGIAHGENPIKFALPLLLLQISVVSLFSMFFQFLLRPFGKFAFLSQILAGICLGPSIIGRNKQYMSTFFYTRSMYIIESFEAICFLFISYVTTCQIDTHMIKRVGRLAFINGIVLFLIPFLWGQFTAVLISKRLGGRPAGVSPAEFHHVAIVQSTMFFQVVYGVLSNLKMLNTEPGRLALASMMVHDCLSWCFFMFNIALKHNTHLADKNHAYYLSAAQMLMIVMIVYVFRPIMEWMMKRTPEGHSLKASYLTVICVLLFISSLWSEFVGLPYFFGAVALGLATPKRPPLGTGLSEKMGCFIWYFLMPCYIIGIGYNMDLSLFSLGDLIRYEILFGMVRFAKVVAVALPSLYYNVPLWHAILVGFIVNIQGIYDVQIYKQNFNYRKISKKTFGAMVMSAMINSTILIVVVKKVYQTMSKRNPYKRRTVQHCRIEAPLRILTCFRQREAVRPVLDLVELSRPAIGSPLSVFALNLEELNNHSLPLLIHHTQEISPFVVPSPRDQIVKAFHNYEKTNPETVLIECFTAVAPRKTMHEDVCTIAFDQETDLVVLTLDAGMESWERLLCRNLLQTCPCSVALFIDRGRLPDFRFVPIKKLCITICAVFLGGPDDREMLAYATRLANHPSVELHVFRLLDQNGASPLRDMVERNHDMRVINVFRKENSENNIIFREVRIEEAVELMELLRKEGDDFDVMMVGIRHEENLLMLEGLSEWSKMKELGELGDLLISKDLQLSVSVLALHQ
The following text describes a protein:
Function:
Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Sequence:
MAPTAKAAKQEKKPDDKKKSSKPRNYDLGNGVMRFSRTRMYHKKALYKFMGKKVKATKKPAKPAFVTKQIGGDKNGKERKVFLKKRRNYYPTQDKIRKHPAKKTFKQHKRHLRSTLTPGTVCILLAGSHKGKRVVFLKQLHSGLLLVTGPMQINSCPLRRISQRYVIGTQTKIDVSGVKIPETINDEYFRRKREKRAKKEEGDIFQAKKEAYKVSDQRKADQKVVDKQVFEAIKKHPDRKVLLAYLSAMFGLRSSQYPHRMQF
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MNSIVVAITENKNGYESGDNDIELQQILFYSTQFHSGKNFESSSNHGVGKKPIEIKYSVIPNSLILKKKTSKKGESSCTVCEICKNVFSLPNKIIRGTNCNHRYCEECIQNYIGKKINKDIHEMISMKCPASDCNGILDIDSIMPVDFLMRVRDVIRLTKVLASPIVIDFPFMDCMGTLVDDLREYLIRACPECWRLFCVNCKCLHLGMTCENYRFGRQLNLLDSQHHYGGYHDELEEDEEEEEEDEDVDDEEGEEEERGGEGEETP