lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
Sequence:
MTKKELIDRVAKKAGAKKKDVKLILDTILETITEALAKGEKVQIVGFGSFEVRKAAARKGVNPQTRKPITIPERKVPKFKPGKALKEKVK
The following text describes a protein:
Function:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MVVLLTFCILLPIIILILLILRFKYQKKRTIAFFHPNCSAGGGGEMVLWVIIKVLLQSFPNYSIVIFTADTSPKDKILEKVKSTFGFDFLDCNIKFYQIKHSYSLVIKKYPFLTLFFQAIGSMICCFDALIKCNAEYFFDTTGCAFTYPFAWLAGAKIMTYTHYPTISTDMLNVVQKREVSINNTNTIARSSILSTMKVFYYKIFAYLYYLVGNLASLVFVNGTWTKNHISQLWKIQPHLLYPPCDINVSNLNEKNSSCHLIISIGQFRPEKRHLVQIEAINILVQEHPEIKNKIKFVVIGGARDAEDLKRKEEVIKTIEKDKLTDIITVPESTSYEQKIEYLKNAEIGLHTMVNEHFGICVVEYMGFGVIPVAHKSAGPELDIVDDQCGYLATTPKEYADAIFKIINDPEKTAQMRQAAIQKAKKFSVSAFEKQCEKELLEFLK
The following text describes a protein:
Function:
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MDSAWVQQLPPELQNDIKAVVEKDQSSFAAFDNLHAFLTGGTTKKRKLNAEPEEIPPETIIFEINEISFYSPVRKRMNLTLHLVEEDGNPSPALSIVNPSNNIPELTFTGLDQAVKLCLLLPILGNTTNTQKKAICYLCFWMHDENMSKDPIVCQMNLDLVKKSMIKNGKLPADIESKFITPRDALPLNPIQERIIDYFKRQFQLCGISMMNYMPCVSIFRNTFSLNDDNAIAMNTDGASQPALVMVNCHKGAKEGVLILLQANKTNPAHIIFGFKKPILVFEASQVLHTSYSNITRQTFSLNVVVLNKKQEQRELEFGMIDEKFYKVIDDFIKLQGINDATFNQEESGDDSIEIVHVNNNDDDDDEEDDDFQSEDSGSDVEEEYNSDLNEPLAAHEEDGVFERGIEIE
The following text describes a protein:
Function:
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MVNNAIKGLKERGGSSLQAIKKFVAANYKVDAEKVAPFIKKYLKGAVASGSLVQTKGKGASGSFKLASSSASGGGAKARAAAAASAARAAAAAAAAATGERKKKSSAVSKVKKNTGKRSAVSAPKTGKKPSSPKAKKVAAEKKSVAVAKAKKAASVGAEKKTTAASSTGRAVAATASSKPKSPSKAKKSNKAGPTKKPKAPKPKSAKAISAKAKKSPASPKRKK
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MGPISDFPLMFIPPAMPSSPSSPELVHSEPNPNPIPEPEPNPESNTSHNAPSSPPQTTTNKPPPTAAEIAARYILQSPPLSFAPKPLSTSEVTAAFGVIDDLPSLTDEEQKPLSSILTTSSGDQFSGTSWWSNQLETGISALADLADLANPSDDDFGYQGYSIHTNLASYNSRKPFEIDNGGWSPVDYGYNFNNFFATASSPRSPSLKSVGAGITNMGNTCFMSAILQCFTHTVQMFLGLRYCTHASSCDVEGFCVICAFRDHLDDALERSRSPIVPRELVKNLNYFSAGFVIGNQEDAHEFMQYALNKLKRGFPVGEENLIDQIFGGRLVSKLRCCCCGHSSDKFEPLIDMSLEIEHVSTIQQALESFTKVEKMDGKFICSDCNQEVTMEKQLMLDKAPSVAAFHLKRFLKDGDSVKKIDKYVDFSKELDLKPYTCGSSSGDNVLLKYELYAVVEHRGPSPNSGHYFSFVRSAPDKWYLMDDDKVSSVSEEEVLNRKAYILFYAQQGTPWFSSIVENEETAPKSKYLHNKYGFDCDNNGEKDDNDSTDANYDNCVSDMDEECDSGMQDVSP
The following text describes a protein:
Function:
Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC) (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus membrane; Multi-pass membrane protein.
Sequence:
MSSAYSVRSFPVSIPAVIMETDWTEPWLLGLLAFHLLCLLLTCFSSQRYKLQIGHFLCLVVLVYSAEYINEVAAVNWRLFSKYQYFDSRGMFISLVFSAPLLFNAMLIVIMWVRKTLTVMTDLKTLQEERKERRRRRKEE
The following text describes a protein:
Function:
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MRRRRRGESGGRPELRLAYGARARSLGRAIIALLPPPPPPDSACPACRGASSGCLACRRWEFLLRDDDPAAYRRLVTRAVCTVAPVGSAPSPPRYSPGNAGNSQAKLVRETIKWILTDRYCRTKNVLCNGCREGAQAKCVSDLVSSPSWDILLHRIGDLLMCYILRHSSIFLPIKKSDYFQVTGVPLNVVLQKPIFASAMARNQQSRPMKGKCLMCYVWRNAMMVQNISGGNRGNGSKFGLYCSDNTQKIDALQSSRSSSDGCNCSNCTQKPRKRKRLYSWQRRSKQKEICYEDRSTELSKLDTSNYRVSDLLSDGSAAESIDRTHSLEPTVDNNSPAINNGVNFSAVEEPCNIPVMSSKKSPSSVMNISPSQGLYCGNSTSGLQRRSPQVPLPSYLQLDSGHFCFNCLMLNASKCVSVDSVISRQAIFYNRKISENVFRRSNLTNKRKRPDALSLIKRIFGIKGCCTKFFQCDCHGLSATNSNCLCHRLVQLLKKLLRNAKRCQYKKLFLRHCSVKSKVVNDGFPSNLAKNEDNIQYSMAGKSACGDKSFAQLEAYSTYQQVVSFVWAVLTRIIPQPLLGNASSKRCLRSNIWKFIKLRRFETFQLTDCIGELNVSNYSWLSEIGFSGCFCSALIKETGLLSGTEEQKQKNLLCCWIRWLFSDIIIPLISTYFYVTERETKRYDVFYYPKSIWRNLTSNTIASLSLQNFRILHGTSRRAIKHLYRASRVRFLPKLKDMRPLVNFKTQSKDVVLNKCHLIIKKLRDENPEVFGSSVFDYDGVHKNLLSFVSSVRSKLKKFKIYIVVADVSKAFDCVNHDVLLKIMDDVLKSDEYVLRKCTKVIYSSSKKAVYRFDSNVSVSKGNSSLDFSIQPSSSGGVLVDQGTVSTIRKEELRRVLFEQVKCNIVKFGQNFYLQQVGIAQGSKLSPNLCSLYYGHLENSVLLNLLHDGNTSSGEDVSVPEYLLMRFIDDFVFISFSKQHALNFFNRMRRGFGYYNSYMNDSKYSFNFDAGYSEHCNNRLYRGDDGVSFIPWSGLLINCENLEIQADYTRYLDITIISTITVKMHSSTKYLSSKLCHYMRPKCHPIFYDSSINSPGTVRLNIYQAFLLCAMKFHCYIWSMADSSISKPELLHILKKTFRYMHGLIVNRTKDVGLQSDVRPVLKLRRKETIWLGLSAYIRVLQKKQSRYKDLLALLTAEVGRFGQMDRSSDSLRYAVDDSHSSMFWKFKY
The following text describes a protein:
Function:
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MAPSYENLPLDDDEFDESNIDFTDIEEQFQVRLDEGLDAFVVIDGLPVVPEDSKGKLVKFVLRKLNTVGKVKEDGVHMPVGDNGKTEGYAFVEYSAPAEAVAAVKQLHGTALDKKHTMAVNKLTDIDRYGKEGRIDEEYHAPEIAPFEQKEHLRWWLGDPDSRDQMAFYRADKVGIFWNEKEETPEQIVDRENWTESFIQWSPRGTYLTSMHAQGVQLWGGKAWSRQKRFAHPGVNLVDYSPGEKYLTTWSHRPLQVDENNPVPSLSLEDDGKNYIIWDIATGKPLRSFQTIDVPAGTDAEGNPVKKKMQWPTFKWSADDQAIHVFVLITTGEVVPNAAVGPKTAVSFFAPEKLKGGAPGNFRHIRTIDKKNSNAIYWSPKGRFVVVAALQSQQSFELDFYDLSFEKPKDESEKGDKELNANLQLMETVEHYGVTDIEWDPTGRYVATVASAFRHRMENGYHLYDFKGTLLREESIEGFKQLLWRPRPPTLLSKEEQAEIRKNLRNYSKVFDEHDLAKRSSANRAVVEARREMLQEWKQWREDVLHRLQEEGADLELSAAKGEAPGKAEDGHLEEIEEIVEEIIEETEEVM
The following text describes a protein:
Function:
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MSEPVVDTAELSAEEKKRLLRERRQAKMSKGKATARLNDILSQGSSVKTSGVKSVLDQEKEATPSHDEDPEIQDITEITTPPPRTPPIGEDAPQDIDKIFQSMLQQQGQGADTAGDPFAQIMKMFNQVEGGDSPPSESATSTQDPAELKYRQELLEYNTYNQKLWKFRFLLVRVSVTLFNFFYHYINLSNFHASNYAYVRDLSSEKYPVRDFFTWFATTEVVLVAAYYSIFHSLGLFHAANQNSFVLKAMSMGSMVLPQLEHYKPLVARFLGYYELLGIVLGDLSLVIVLFGLLSFAN
The following text describes a protein:
Function:
Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
Subcellular Localization:
Secreted.
Sequence:
MSLAKKSMNPSQRQNRHPGDGPRPSFGGFQPLRYCFSDSTIKSIKLMKCTIRDPNQQVLVLENGVLKAVPDKGTTTPETFYISTSQLSTTSIKKENHIFLAVSKGELCLHCDTVKDPEHPSLQLKKKNIKELNSLNSKESLPFTFLKEQIGSYFTLESAANHGYFIYTSNIPRQPVGVTKDLGKEKNTQFEFENISVNLSVVQDGVYKLTMAKPCMTMEL
The following text describes a protein:
Function:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MEAAMGLMRRIPPKHTETALSALLSLLPEHSSDLLSQVDQPLQVLCDMESGKEFILCEYNRDADSYRSPIPGNFLPDVHIMEHLNMQCTSDDPLSPSSQSLWDSIQQNTTPRSPWSNKYHPPLEDAPQPSLELRKLEVEANEVFAVYRDQYYEGGISSVYMWEDENEGFVACFLIKKDGSKTGHGRRGYLQEGAWDAIHVIEVGPEEEEIVQYCLTSTVMLTLTTDNESSGSFNLSGSIRRQMSMKLSVSEGHLCNMGKMIEEMEGKLRNSLDQVYFGKTNEMVCTLRPPAELVQMKLPDA
The following text describes a protein:
Function:
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Sequence:
MIERKDKFYKEFLENNLFYATIILNLNGASIAYNKSPQMGEADQIIKGFKNIKKWNTIQLMGEQYNIYIRENNRVYGQNEKHGCIVVKTKKAYIIGVYIKKLELLPRVSYMEKFCKTYEEEDIIKADEKEKFVF
The following text describes a protein:
Function:
Required for the immune deficiency pathway, which mediates responses to Gram-negative bacterial infection. Favors Rel activation and nuclear translocation.
Sequence:
MLARCVSYQGSCDNINGILTRDYAEIYTDWANYYLERAKSKRKVTDLSADCRDGLLLAEVIEAVTSFKVPDLVKKPKNQQQMFDNVNSCLHVLRSQSVGGLENITTNDICAGRLKAVLALFFALSRFKQQAKQTKSIGVGCGGGVGGSSSTLTGSGSVLGIGIGGLRTPGSSLNQDKNQQEQQQQQQQQQTPQQLAQSLENGNEMVNRQIAPAYAKVNGGTAIPLPATVMVQRRCPPDKVRPLPPTPNHTPSIPGLGKSGSDFNTSRPNSPPTSNHTIQSLKSGNNNSLRPPSIKSGIPSPSSPQTAPQKHSMLDKLKLFNKEKQQNAVNAASVASKTQIQSKRTSSSSGFSSARSERSDSSLSLNDGHGSQLKPPSISVSSQKPQPKTKQSKLLAAQQKKEQANKATKLDKKEKSPARSLNKEESGNESRSSTMGRTGKSSLVRAVGGVEKNTPKTSSKSSLHSKSDSKSSLKAPQLLQSPSSGGLPKPIAAIKGTSKLPSLGGGAGHLPAAESQQNQQLLKRETSDISSNISQPPPAEPPISTHAHIHQNQTPPPPYYANSQPTSHISSHGFLSEPSTPQHSSGIYGSSRLPPPKSALSAPRKLEYNAGPHILSSPTHHQRQGLPRPLVNSAPNTPTASPNKFHTIPSKIVGTIYESKEEQLLPAPPPASGGSSILPMRPLLRGYNSHVTLPTRGARGGHHPHQSYLDFCESDIGQGYCSDGDALRVGSSPGGSRFHDIDNGYLSEGSSGLNGPSSSAGGISPGKHFLSMMRARTQLPTTIEERIRNSRGSLDSIGTAANGSSAASQASSSGGSTTTHAQNNNNNNNNNSGGGAKMDGSPHHRPGSRNGRDNWSKMPEPLNGQKVEKSDKSSPSRRSMGGGGSGSSSKQGSPSSSSRTKGVPPSFGYVKRANGSIASTAEQQNIAMMMAAGGAGANGLPCGRTAHVSAVPRTASGRKVAGGTQTLPNDMNKLPPNTQHRSFSLTGPTATQLSQSIRERLATGSHSLPKPGSDLHVFQHRISNRGGTRHDGSLSDTQTYAEVKPEYSSYAMWLKHSNTAGSRLSDGESVEQLQIGSPALTRHGHKMIHNRSGGPGQMAGQMSGNESPYVQSPRMNRSNSIRSTKSEKMYPSMMSRAGEVEIEPYYCLPVGTNGVLTAQMAAAMAAQSQAAQGNPGVGVNVGGVAWSQPTSPTPLTRGPFNTAAGASVLSPTHGTTSAAGLVGPGGGAGGGAMVGHRLTYPKKNDEVHGSAASLLSGGSSLYGNAEERQAHEIRRLKRELQDARDQVLSLSSQLSTNAHVVTAFEQSLSNMTNRLHQLTATAERKDGELTDMRQTIELLRKQSIQAGLTTAHMQSMGVQTQGQGQVQGQALGQALGQPGSDQKPPNSGSQRAINANNGSMPLGMQRQHSTDSMCSLNSISSGCSAAQDKNKANKKKGWLRSSFTKAFSRNAKISKTSRHVGHHHHHNHSQQELASGKLPLHNGHGEPLGLASLATQPAPPLPNSKQSSPAKTVTLIDNAKPIDAIDQEDQHVVEDLKKQLREKDLVLTDIRLEALSSASQLESLKEMMNKMRAEMMSLKHNNERLQKLVTTRSLAGSEASLGQAISPNGSVAGSSEVSRRYSLADSNSRPPMELPARLSEELELEEDCLPPAPAPEQPPPPAPNGVSVAPLSPSTHVDLTPPPPALEAAPMASPVHMASATEELADVCDGKKIAIACYLGQPEAFAKYCEELQELDGFYANGHEADSQSQSERKSNYTSASCNEFVIACTYISGKTTWQNLDYVVRKTFKDYVARIDPGTNLGLNTDSITSYHLGEAKRGPEMGFPELLPCGYIVGSVRTLYICLQGVGSLAFDSLIPRSIVHRYISLLTEHRRLILCGPSGTGKSYLARRLAEFLVARSARGNPSEAIATFNVDHKSSKDLRQYLGHIAEQAAIANGVSELPSVIILDNLHHASALGDVFSCLLSAGPANKLPCIIGTMSQATCNTTNLQLHHNFRWVLTANHMEPVKGFLGRFLRRRLFQLELQTQHPQPELAAVLAWLPSVWQHINRFLEVHSSSDVTIGPRLFLACPMDLKDSQVWFTDIWNYHLSPYLVEAVREGVQLYGRRGGAWNDPSAFIRNSYPWPYGPDSVPPLRQINAEDVGLEGVALTNGDQQDPLLNMLMRLQEAANYSEAQDQESDCASLDSNVTPESSAGAE
The following text describes a protein:
Function:
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MNSENSFSSSEHITVLLHEAVNGLALKENGIYIDGTFGRGGHSRFILSQLSSNGRLIAVDRDPRAIAEAHKIQDLRFQIEHNSFSHIPEICDKLNLVGKIDGILLDLGVSSPQLDEAERGFSFMKDGPLDMRMDTTQGLSAEEWLKQVSIEDLTWVLKTFGEERFAKRIATAIVDFNKSAVKNGTEFLSRTSQLAELISQAVPFKDKHKHPATRSFQAIRIFINSELDELESLLNSALDMLAPEGRLSIISFHSLEDRMVKHFMKKQSKGEDIPKGLPLREDQIQRNQKLRIIGKAIQPSDAEIQANPRSRSAILRVAERI
The following text describes a protein:
Function:
Plays an essential role in phage DNA replication by participating in the removal of DNA-linked RNA primers. Participates also in T7 DNA packaging, host DNA degradation and phage genetic recombination.
Sequence:
MALLDLKQFYELREGCDDKGILVMDGDWLVFQAMSAAEFDASWEEEIWHRCCDHAKARQILEDSIKSYETRKKAWAGAPIVLAFTDSVNWRKELVDPNYKANRKAVKKPVGYFEFLDALFEREEFYCIREPMLEGDDVMGVIASNPSAFGARKAVIISCDKDFKTIPNCDFLWCTTGNILTQTEESADWWHLFQTIKGDITDGYSGIAGWGDTAEDFLNNPFITEPKTSVLKSGKNKGQEVTKWVKRDPEPHETLWDCIKSIGAKAGMTEEDIIKQGQMARILRFNEYNFIDKEIYLWRP
The following text describes a protein:
Function:
Transcription factor involved in the regulation of root hair elongation. Is sufficient to promote postmitotic cell growth in root-hair cells and is a direct transcriptional target of RHD6 and RSL1. Involved in the regulation of root hair elongation in response to low phosphate. Controls root hair cell growth by regulating the expression of genes encoding proteins involved in cell signaling, cell wall modification and secretion.
Subcellular Localization:
Nucleus.
Domain:
D-box [RxxLxxxN] motif functions as a recognition motif for the ubiquitination machinery.
Sequence:
MDVFVDGELESLLGMFNFDQCSSSKEERPRDELLGLSSLYNGHLHQHQHHNNVLSSDHHAFLLPDMFPFGAMPGGNLPAMLDSWDQSHHLQETSSLKRKLLDVENLCKTNSNCDVTRQELAKSKKKQRVSSESNTVDESNTNWVDGQSLSNSSDDEKASVTSVKGKTRATKGTATDPQSLYARKRREKINERLKTLQNLVPNGTKVDISTMLEEAVHYVKFLQLQIKLLSSDDLWMYAPLAYNGLDMGFHHNLLSRLM
The following text describes a protein:
Function:
Non-catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. The TSC-TBC complex acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. In absence of nutrients, the TSC-TBC complex inhibits mTORC1, thereby preventing phosphorylation of ribosomal protein S6 kinase (RPS6KB1 and RPS6KB2) and EIF4EBP1 (4E-BP1) by the mTORC1 signaling. The TSC-TBC complex is inactivated in response to nutrients, relieving inhibition of mTORC1.
Subcellular Localization:
Cytoplasm, cytosol. Lysosome membrane.
Sequence:
MRRDFRTAYLNALGFKGGSQLKTSLEAIFEHRVIDLGKLKKICNLFDIPNQYRSKVWRILLGVTSSYQESWDLVLEQRTIEYEDIKDAVLSVKRNLTVPLNSFYSSWKENSQSTDEQVIKNAIQLASTGLTIIYTTKEQYFNYQNSLYYIATAANLNQANNNIQNNQNNNQNHNTNTNNNTNNQISNHNNNNNSNNHYQHNNTHHNNQHNQHNQNSTSFQKKPQMDLSFSIFDLQKANSNDNKNNNNNNKNNNNNNNNNFNHNSGISKHDLDDLIKRYTTQMNVNNNNKSNLQEFQVDETLRSMAEVFCYVCESEVDAYWCLNNFLNLPLKQYGHKDIGLCHQINSLTRLLEIHDRGLSFHFKHHKIHVDMFSTVWFKSFFTCCFPTNSMDRIWDRIIGVSLDYMAYISLAILQSKKPLILDKTNKTDILNYLLNKDLNVDMILEKSVELFGVSVNEETDPDE
The following text describes a protein:
Function:
Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLRARSAVSQSWKGFKTFSCVAVEVKNEPVLEFKEGSKERAELEEALRNLKGKTEEIPCVIGNEEVWTKDIRFQLSPFNHSHQVAKFCYADKDLLNKAIEASVAARREWDLKPVSDRAQIFFKAADIISGPKRAEVLAKTMIGQGKTVVQAEIDAAPELIDFFRFNAKHAIELEDQQPLDSDGSTNTMLYRGLEGFVAAVAPFNFTAIGGNLAGTPALMGNVVLWKPSDTAMSASYAVYKILRESGLPPNIIQFVPADGPVFGDTVTSSEHLAGINFTGSVPTFKRLWKQVAQNLDIYKNFPRVAGECGGKNFHFVHKSADVRSVVTGTIRSAFEYGGQKCSACSRMYVPDSLWPQIRQGLLDVYKQIKVGDPVEDFSTFFSAVIDDKSFSRIKGWLEHARSSPHLKIIAGGNCDDKKGYFVEPTIIETTDPQEKIMNEEIFGPVLTVYVYPENDYKKVLHLIDNTSPYALTGAIFPQDKSVIEEAGKALRNAAGNYYINDKSTGSIVAQQPFGGARASGTNDKPGGPHYVLRWTSPQVVKQTHVPLTEWKYPYMS
The following text describes a protein:
Function:
Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSAEGEWSCDANDAVQITIVHPDQQKPKTLSSFHPQFTYPIFGEEERIFGYKGLIIRLRFAAHNLRPHVHVSYDEKFTAVDDAEPVDIIGALKEFLPEEAFSSLPEFESAVQEEDAKEFVPPGKLSHSYSIRGRNYEIWAASLADPQVQLLLNRFQIMVSFYIEAGTPLSTDDPEWTLDRWTVYFVLTAARYEKVEPPTPTASSYSIVGYATTYRWWFYKRDRSENPMPRDGPFPPPELVRPGELPSRLRIAQFLILPPHQGTGHGVNLYNTIHKTCLDDPTIMELTVEDPNESFDVLRDSADYHILRPEFLKHNIQINPDPWSDFSKKTKRVPTSSLLPLKTLNEIRTAYKIEPTQFAHIQEMFLLGQIPLKNRRKGGANMARLLVKKYRDDDPNNRRYYWWRMLTKQRLYKRSRDVLIQLKMSERHKALEDTVTNVEDGYEQLFGFFNEREERLRAQQEEAETSNNRDQRTKRKFTVEDEDDEDESAAAKRPKA
The following text describes a protein:
Function:
May play a role in plant defense. Probably has no oxalate oxidase activity even if the active site is conserved.
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MAAIPSLLRRLAIVVATTAMVILLPSPSVAGDPDLLQDICVADLTSTVKVNGYACKAAAAVTADDFYFSGLGGAGNTSASAYGSAVTGANVEKVPGLNTLGVSMSRIDYAPGGGLNPPHTHPRATEMVFVLQGTLDVGFVTAANNRLVARTLAPGDVFVFPRGLVHFQRNAGDGPAAVLSAFNSQLPGTQSLAAALFAASPELPDAVLAKAFQVGTKEVDKIKARLAPKKA
The following text describes a protein:
Function:
GABA-dependent positive regulation of genes required for catabolism of GABA (UGA4, UGA1, and UGA2).
Miscellaneous:
MISCELLANEOUS: Present with 1200 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MNYGVEKLKLKYSKHGCITCKIRKKRCSEDKPVCRDCRRLSFPCIYISESVDKQSLKKIKADIQHQLISKKRKHAPDSAQKAAVATRTRRVGSDEQDNQVYLSKPLEDCISQKLDSMGLQLYNYYRSHLANIISIAPMNQNYYLNIFLPMAHENDGILFAILAWSANHLSISSSNELRKDEIFVNLANKYTYMSLSHLKTNEGSSACAKLGFLYSLAQILILCGSEICQGDVKFWKILLNIGKNLIENHVGKDVSRILTTTTEEPSLEERIIFPNFNSVVKYWLIVNFIYHDILNFNTTSFPIEQYEKFFQRDQNSLPSSANFIESIDSPIEEIDPLIGINKPILLLLGQVTNLTRFLQTMEQEEMLEHGDKILSLQVEIYKLQPSLMALEHLDDEKKFYYLELFEIMKISTLMFFQLTLLKIDKDSLELQILRNKLDSKLDKVIGTFLEGSLCFPLFIYGVCIQVEDMEKKIDLEAKFDDILKRYKCYNFQNARLLIRKIWQNEADGISEHDLVHMIDELDYNINFA
The following text describes a protein:
Function:
Part of the ABC transporter DppABCDF involved in dipeptide transport. Responsible for the translocation of the substrate across the membrane (Probable); When a foreign outer membrane heme receptor is expressed in E.coli, DppABCDF can also transport heme and its precursor, 5-aminolevulinic acid (ALA), from the periplasm into the cytoplasm.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ
The following text describes a protein:
Function:
Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation.
Sequence:
MTNISLTIKAANDQKYAVTVDSESSVLALKEAIAPVADIEKERQRLIYAGRVLKDEESLKTYKIQDGHSIHLVKTLGQNPAAAATNVSDRTQQVPTNIQAGQGANNPLANLTSARYAGFNIPMPSASMFGPNPENPVPPSTEELANMLSNPMVQSSINEMFSNPQMLDMIINSSPHLRNAPPYVRQMMQSPEFRRAMTDPDTMRQMAQLHQQMGAAGIDPMSLMGGGLGGAGLGGLGGAGLGGFGGANNATAGIAGAAPVDQTAAANTIQNLLNNLGGAGFGAGLGDAGLGAGLGGAASPPAPAQDTRPPEERYAEQLSQLNEMGFVDFERNVQALRRSGGNVQGAIESLLSDL
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDPQPPPPAQGSPPHRDRGRGRGRGRGRGRGRGRGRGGAGAPRAPLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGHGPQPPLRCAACPRTFPEPAQLRRHLAQEHAGGEMDLTTQRAVKEEPEASWGPQDEGVEQPSTVVVAGVAEEATAQWPAGDPASVAAPTSTDPRESEAEEAEAGAAELRAELALAAGRQEEKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGEQEGEGGPPPRPKRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCPDCGLAFRLASYLRQHRRVHGPLSLLAPLPGASKKDDKASGGRNSGKGPEGVEGAECGGASEGGEGGQNGGDATPARPPAGEPRFWCPECGKGFRRRAHLRQHGVTHSGARPFQCVRCQREFKRLADLARHAQVHAGGPAPHPCPRCPRRFSRAYSLLRHQRCHRAELERAELERAAALQALQTQAIQSSQPPQPFKQEAEGLPLPISHIKEEPPSPGTPPQSPPAPPVFLSASCFDSQDHSAFEMEDEEVDSKAHLCGLGDLAS
The following text describes a protein:
Function:
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
Subcellular Localization:
Peroxisome.
Sequence:
MATLIDNRYGKARVRVLRVFKGPNDHHKIFDFDCRVLLRGDEFQETYLTGDNSKVVATDTMKNTVYVIAQKEEFKSLEEFGIILGRHFINTYSWVSGVEVSMKENMWHRIVTSNGKPHGHSFTRDREVHTAVVTSTRGKSPVVVSGIDDVLIMKTTQSGFEGFHRDKYTSLKETKDRVFATVVTSNWTYNTLDVDYTKAYETLKQSVFDIFANTYSKSVQETLFLIAKDAIGKCSAIEQVHLSLPNKHAFGFDFSRLNIENKNVVFQPVEEPSGLIEGTIKRVHARL
The following text describes a protein:
Function:
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
Subcellular Localization:
Nucleus.
Sequence:
MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK
The following text describes a protein:
Function:
Not involved in actin polymerisation, instead functions to stimulate nucleotide exchange on monomeric actin and influence turnover of the small amount of cytosolic actin microfilaments. Essential for erythrocytic schizogony (By similarity).
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton.
Sequence:
MVSGVKVSDECVYEFNKLKIKHIHKYIIYRIENYEEVIVDFLEQDNSLKSYKDIIIDIRNNLKTTECRYIIADMPIPTPEGVLRNRIYFIFWSPDLAKSKEKMLYASSKEYLVRKINGIFKSLEITCDLEDFEDELRTIILNT
The following text describes a protein:
Function:
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
Subcellular Localization:
Golgi apparatus, trans-Golgi network.
Sequence:
MEEDYAKRSERVKALLSQYYGDGSAGPAAGAPGQSAQQPSAAPGRGQQGGHVAGLAAIDTPTFNADQHTSDILRIFSLEKLMVEHRNMAREIKNLDSDMQQLVYENYNKFITATDTIRTMKSSVDNMESEMQRLEQTASVVAEKSLSVSNKLQQRRESMEQLYKVQRLLRKLQTVFELPRKMRAALEEDALDTAVGLYAEAQPLLHKYGNRGTFKVIALESDFVAQEISQLLKKRLTERKDDAEQCVLLLRKLGEPDDTLQDKYLSGRVARIKRVLAEAAVVADAMAAAASGQQQVPLPNKAQVAAPEAWNWTAAGPPPLRAFVRSLDEKFISGVQETVVNVIRFFLPEGSEDSPEAAAAKRKPLVALSRELFTEYFGIIRRVVTDAAKAGVLRGSLLREARAEAAAAAGGKGGPGGAAAVLSVNSPSLQQLGSDWGAEPIAQALSTVSTDVGLLATHLPELGLKERAAEVVQAAVQQHVTLSFAALKQRVIDAAVCVRTALQGAPGGGAAQGGAEAGAGSGGGGGSGAGGGGGGGGEARGGVLRAGSEYLVELLQRGLAALLQGLRGYESAGGPRLLASWRDAWVELVQGGLQGFFVGLLTASLELAALRYDGGDLMREALKAGSGTAATAGPDLMGPPPGAAAGGQELLVKPALVLLLAKLCKFLEQVMVPWVMETIAASFASSGGPGGGPGGSVDMPPAFVPGEVARRLSAASSAMVLAYVEMHGRQLSVMVRRSTGSVSWLTCKEPRGPRPVCSLLLERLAKLQAEAAALLEEGDGVASMLGGGGGGPGRKSDEHHRGAGDGRGMYGGAGAFGGGDTAAVERNVAKLFREKVHMTGSVALTCPAILAAVAAVALKSLLESIRLETLGRAGLQQLQLDVAFLRPQLRRCLLRGGGGKGDGTAVVEQLLEDVVLSGTERCVEPALLEAAVVERILASASSAEDR