lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase component of the GID E3 ligase complex recruiting N termini and catalyzing ubiquitination of proteins targeted for degradation. GID E3 is regulated through assembly with interchangeable N-degron-binding substrate receptors induced by distinct environmental perturbations. Required for the adaptation to the presence of glucose in the growth medium; mediates in association with the substrate receptor VID24/GID4 the degradation of enzymes involved in gluconeogenesis when cells are shifted to glucose-containing medium. Required for proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBP1), malate dehydrogenase (MDH2), and other gluconeogenic enzymes.
Subcellular Localization:
Cytoplasm.
Sequence:
MSELLDSFETEFAKFYTDSNLEETNLQKCLDHTHEFKSQLKKLKAHLNKHIQESKPEVYNKLSDKEKQKFKRKRELIIEKLSKSQRQWDHSVKKQIKYVSQQSNRFNKSTLNKLKEFDIDSVYVNKLPKETMENVNEAIGYHILRYSIDNMPLGNKNEAFQYLKDVYGITNKESTEFIEMGQIVHDLKKGDTESCLKWCSNEMESLSSNHTALSSLKFDLYTLSAMQIVKHGNPVELYYQITQNAPLDCFRHREKELMQNVVPLLTKSLIGQPIEDIDSKVNKELKECTSLFIKEYCAAKHIFFDSPLFLIVLSGLISFQFFIKYKTIRELAHVDWTTKDELPFDVKLPDFLTHFHPIFICPVLKEETTTENPPYSLACHHIISKKALDRLSKNGTITFKCPYCPVNTSMSSTKKVRFVML
The following text describes a protein:
Function:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MIFNVSHGFQNLKAPTNNPKTESFSLLPADTVIVIENAPEVGTSTSSKAFKDVAYSFNDEEEEQKPKPKFEMNGSNGFLSKTTLRLDNQEMTKEEQRRQHQAELACQKNEETARRLASGIGSSDGHGAVRTSNDLIAYKNVDDVMNLKEVMIYVDQKNEAILLPIHGSLVPFHIATVKSVTSQQDCNRGYEMEAEWAIYIKEVTFRSKDARHINEKVQLIKNLRKRVASRESERAERATLVTQEKLQLSKTIPIRLSDLKIRPAFEGQGESVDIMYANIKHVFFQAAEREMITLLHFHLHNHIMVGKKKAKDVQFYVEPHQRNLQLDFDQPLREPGFHGVPQKSSAFIIPTPNCLIELIETPFLVITLSEVEIVNIERVGLGQKAFDMAMVFKNFKKDVLRIDAIPIAALDGIKEWLNIINVKYYESKMNLTWRIILKTISEDPEKFIEGGGWEFLNLEASDSDTENSEESDVGYEPSDVEEVSHSEDEESDSESLVDSDEGDVEDKDSDDLEGKSWDE
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MTAVSNIIATFIGLVVATLLLSRGTQADPAAELTKQDTPCKSAHYLIKLAAAAEGKLKSLLEKTTEAVDEHRALEVYAATTDTGAANAAIAGLSEYASRRTATLAKAAVTCAQAVSQLTRTLNIEAGKNLALSSATEIKSATGTAQAMSNTGQGQSVSGHLKLDKLTDDSCAKTYTATAANTDNDPDTRQLESIRIHKLEGKTTADTAAGVCQVACVGAACSTAETNIKVSSAAATLFKAGELAQLAVKTTDAKPKRSDTPQGLKKELEKHQTSIEHRLYDFLKNKPCDADMASVRNMAVVQNDEGVRKAVLIELQGPAAKYDASSDSQKKAITDGIKAMFGGTETEFNAKIWEKVKANSVKQKIAGTDIDSKIEQLSTDTNRGLVLAYHASQRKNKPSCKTETSTQKPQQCGSQTTPEHCQKEGCYLDENKTPKCFPKKSKDDKKNGDYAKATNTTGSNSFVIHKAPLLIAVLLF
The following text describes a protein:
Function:
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
Sequence:
MGEINNNKEINEKDDEINNKRLKYEGFIKKEKKKKQKIDHSIPLKEKPTQEDIDSHSECLFWIVNKKKHRAEFCKYKRAKDSILCNHHKPIDQISSEPQPQLTDYNGDDVTENNNNSTTTTTATTQDDNSKPKERKRIHCPLNPTHIIYECKLQKHLKACPNAKVGQKNAHIELSKKEPYYKENINDLNENVKLTLEPIILSQVSTENLINISIKLDQFFEKFFKNEIQSLNQTHKSFDKIFNSDQQLKHIQQESSIINLLENSNLYNSDNVYLEFGAGSGKLSNHIFMSHEKKSGHILIDRMKFRSLKKVDRLIKNEKGCHHFSRLLIDIRHLNLSNLSILEEKPFVITSKHLCGCATDFTLDSIFNLLNNSNEKVNNNFKGIGIATCCHHICNFNTYSNQSYLKDQLNITPLEFQLICSISSWATIDENKCNNDDDDNEVEEDDELIKKDKKEKKEFENQLKIEFNKQDVFSIKRKEELGYKAKRLIDYGRYLFIKEKLNLPNTKFWIYTNQSKENLFLVSNK
The following text describes a protein:
Function:
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to muscle actomyosin ATPase activity.
Sequence:
MSEEAGEDAQRKAAEREAKKAEVRKRLEEAGNKKKAKKGFLTPERKKKLRKLLMVKAAEDLKRQQLLKEQERQKALADRTISLPNVDSIDDKGQLEKIYNDLWARLTQLEEEKYDINYVVSQTEAEINSLTIEVNDLRGKFVKPSLKKVSKYDNKFKKSGESKAGTKEDFRANLKIVKKDVMEAIVNVKKKDDKPDWSKKNKDAKAEDSAPAAVAPEAEPVAEEAEAEPEAEEEEGEEEEEE
The following text describes a protein:
Function:
May have an important role in the development and/or progression of some cancers.
Subcellular Localization:
Nucleus.
Sequence:
MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCPVPFPETFNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQCFGWDDDEDDDDEEEEDDY
The following text describes a protein:
Function:
May play an important role in the regulation of microtubule assembly and interaction.
Miscellaneous:
MISCELLANEOUS: Phosphorylation of various serine residues may play a regulatory role. The basic domain contains numerous sequences that match known consensus sequences of several different protein kinases.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Associated with cytoplasmic microtubules and with the mitotic spindle.
Sequence:
MEHHEDNAQLDNYLQNRLAESLQICGGAGEHNPHLADATGGNGCAPGIAPSKSDEVDGEEDEEWKYIHEVRQSEKLQQEKLPLTKETGNGFGPGRDSDNQVHGNGAAAVFNLYEEDVEVIKNDGDFSTNSNTTTSTDEVVARQAQEPNQLPEQLQQQQQIESQGVHEDPRQEDEDEHSSVATTYGTSSLSENNSSPLDQEEVVMVAQTVGQEQLVDFDNKENSYFVKNLEENHSQLNPNAVAFVPGVGSQSSSPLPAAEDPLPGVQPRPFLPGGTLDDLVAESPRKEFARINMDGIAVPDEREFDIEADMRPHELEQESDTFGAGHLEMQLLNGIGTADQAALRDVLDHGPETSVDMELPLDQVPNDADIMKQSIYAEHNSSIEDILNSVQPLPIQTCDDKELIHVEEKEHVSKSPSTEELQFQSDFPNNQESHTLFNNTEQDPMQASFYLEHTSQKAQEGCQEQMQLPAECSDIFADQSLLLDTSAPQLSSEADSPVAKLELESQQAGIVDITPSPLSSTAEKHLVEDTKELVEEYTLDPESHFFGVVSSQAPLQLFGKHTLPSIIHSCKHRVASEQNDEENAVFESVSGYETQNFDEISSPPEGINPFAQPFTPAHLVIEQANTMMEDVGGMPIPASEDFAICDKVASKSSNEVEDHRSEQQAFVKEELLHPVGDVVAQVENLGTEKNFVVEEERLPISVSDEIPLSSASKEKLLPDTTDEQLLTSALEEKLRSVAPEESVSTAADGQSISQFDEYVIASNKPLEDILEPEKDVEVAKSLSEKTSVATVAGGAVVGATKTHSATKAGSTAASAKSKTETLVMKKTTASSTSVYGANKSAAPRPSTARLGIKSTSIATKTSTTSSLTGNPRKSLSSNVGSTVKPPTKLSGTRPATAPVSKVTLGAKTITNKPTASGTASDNVTRTTLRPLVSTNARRPATSGTGSVASSTARRPVTNAKGSAPGSAASTKVRPAATMTAPVKPKVLSPRSTISSTTTVRKVPSTSTPSFSTRSPNKQQSNGLGKNTSSTTTSTATATITKSFTARSAPKFTHSASLTYNNGSTSRRLLVPGSSSTTTTSSLRKSSPLKAAPGKAASKPLTPQSKDGTAKSSPAVLKARNSTLMGGEGVAPSNECVPTPNGQINAEEVVKLKGKGLAEEVKIIEEQKLHEQDVPAHNAEVPLLDF
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MLYTKLGSPFRLVRPTAAARQLSTLSNRSAIRARIVLTAVSANLLQATSSSLQSARWAPLDRHPGLSQAFRGLSQSTKATEAATAAATSTKEPFELENVAATDSSESEISQQSTKRIKDETFASLKGSVNPSILKALTVKPFAYTNMSAVQQSVLHLLPEIADSVGESAAPMPDGQGRDMLVKAKTGTGKTIAFLVPALEARLRSIEDVRKGKFPKPWSEMLERHRPGLDVSSLQKKELDEIVKQFVNNTVGALVLSPTRELATQIADEAKKLLSHKPELKVQLLVGGASRNFQINDWRRSRPDVVVATPGRILDLLNDVGMIREAMTACRTLILDEADTLLEMGFRDDLQAIMRHLPAKVDRQNMLFSATVSPEIRAIARASLQKDHRFIDCVPAGEENVHKHIPQYATVLESAEEQIPHVVRLIAHDQLINPGKSKTIVFAPTTKMTELLADVIRGVQRHLPASTGSNVYEIHSKKDQRARFNTSDRFRKDQSGASVLVTSDVSARGVDYPGTTRVIQVGIPSSKDQYIHRIGRTGRAGAQGRSDIVLQNFERGFLYYQLDDLPVTQLHVDDLVQEVETLSKRFDEAPEEFAVPEELVKAAKAKAKGYVVKKGVRGRDEVVRAAKPPAQICGPLTGKYSTKTLMPLIEDSLQSLEEEDAVRETFNSLLGFYLGKGDELRTSKMSVLEGVKQWSVEAGRLEQPPYLSDAFMQKLGISLRDRNGGSGFSRRHGGGGNSRSFGRGRFSKDEDAGGSGGRFAIDGRGRTGSRSSGGRGSSWGSGRDARESRFSRDSSSSKW
The following text describes a protein:
Function:
Preferentially hydrolyzes para-nitrophenyl-beta-D-galactoside. Can hydrolyze para-nitrophenyl-beta-D-fucoside with 5 time less efficiency.
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MVLNFRDKSCIFLAILCCLSLSCIVKASVSYDRKAVIINGQRRILLSGSIHYPRSTPEMWPGLIQKAKEGGLDVIETYVFWNGHEPSPGQYYFGDRYDLVKFIKLVHQAGLYVNLRIGPYVCAEWNFGGFPVWLKFVPGMAFRTDNEPFKAAMKKFTEKIVWMMKAEKLFQTQGGPIILAQIENEYGPVEWEIGAPGKAYTKWVAQMALGLSTGVPWIMCKQEDAPGPIIDTCNGYYCEDFKPNSINKPKMWTENWTGWYTDFGGAVPYRPVEDIAYSVARFIQKGGSLVNYYMYHGGTNFDRTAGEFMASSYDYDAPLDEYGLPREPKYSHLKALHKAIKLSEPALLSADATVTSLGAKQEAYVFWSKSSCAAFLSNKDENSAARVLFRGFPYDLPPWSVSILPDCKTEVYNTAKVNAPSVHRNMVPTGTKFSWGSFNEATPTANEAGTFARNGLVEQISMTWDKSDYFWYITDITIGSGETFLKTGDSPLLTVMSAGHALHVFVNGQLSGTAYGGLDHPKLTFSQKIKLHAGVNKIALLSVAVGLPNVGTHFEQWNKGVLGPVTLKGVNSGTWDMSKWKWSYKIGVKGEALSLHTNTESSGVRWTQGSFVAKKQPLTWYKSTFATPAGNEPLALDMNTMGKGQVWINGRNIGRHWPAYKAQGSCGRCNYAGTFDAKKCLSNCGEASQRWYHVPRSWLKSQNLIVVFEELGGDPNGISLVKRT
The following text describes a protein:
Function:
Subunit of the tubulin polyglutamylase complex (TPGC). The complex mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Associated with microtubules.
Sequence:
MEETTPPLQAGSKPHLEKLTLGVTRILESSPGVTEVSIIEKLPAERHVISSWEQKNNCVMPEDVRNFYLMTNGFHMTWSVKLDEHIIPLGSMVINGISKLTQLIQSSVYSLPNAPTLADLEDDTQEGNEDHQLEKPHFDCRSAIFELDSCNGNGKVCLVYKNGKPGLAHDTEIWFLDRALYWHFLTDTFIAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTSLLTEESDNFANKLDPSKVFKSKNKILIPKKKGPVPPASGQKGPGPLPPPTSKPTTGSGNPVRK
The following text describes a protein:
Function:
Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Sequence:
INGTVTIRQCTPDDAEKIKEVLVMWADVMKLDLILTTGGTGFSERDVTPEATRAVITKEAPGMAVAIIQKSLEVTPMAMLSRLVCGIRNQTLIINLPGSFKGSQECLQFASPAIPHAIDQLRGCKEKTDKFHASLSCTAKDSPINLSSEKREPGVANRPRHSPYPLLSVKEAQDIVLRECFKTGIEAVAFKGTKLGPAELGLLATVGRTTVNVFCLPSVAVLSTGNELVVPGSDVQPGKIRDSNKTTLLSLLSSNGFEAIDAGIALDSRADLCGKLRRAFEAADVLVSSGGVSMGEKDLLKAVLSEEFQATVHFGRVFMKPGKPTTFATLQYLGRPKLVFGLPGNPVSATVTCHLYVLPALRRMSHHINVFPTEITAKLADDIQLDPRPEYHRAVLNWSPGSLPVATSSGNQISSRLLSFRGVNALIVLPGSKEGAETFRAGSLVTALVTDRL
The following text describes a protein:
Function:
Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins.
Sequence:
MQNVSRDLQAALRGCSAKEQNQQELLDRVTQERAIGSLVQRGDVSALVVQRIWRGRTVARKVAAQARVEWDEKFLSRHSEDESPVSANVISNQILRPLFMILKPSSPFNLRQIAEDAGRLTTCFRLLLQSIHNPDMRFNYCNLSVGSPEEMSKWMYQARELLRLACAALQKESYADQKGTKTNHLAQADSNLARLAIQVMVSLTDSSTWKCLGGPEQVVRKRKADLVVLSLLEWLASESAGFFLAVRSYILENFLVPGIKNQEVSPCGKEDKLIITALLRPLLVLSAECRKDGKGAENSKNYKDYTFAAERAAALFSVHILTIPFLTQRLPQPLLPALQDPLVLSPCLRFFEVPIRDPPQIVTATSVLPCLPSFQGRVDCELVDVPLSAWALSNVVCLASHTLKHNPRFMKSSPCQKYVQALCCLLEDLNMWIETIRKRREAEKSVSEEEGDKDVENTKNVVIGDVISKSCEGIIIQLLVESLSPLHQQWHLVELVEKATFNQSTPMVFISVAKGSIKGAKEKLFTLSDVAKIYSILLQVFAVLNPFGGALPIVNLIAFTPSIVPLLWSWLHASPGLAHLLKLNLQEQGNAKHQLETQAIQAEKAILIRTGVGVWAAVLGLRNKLTRHDAALERRAVNERTETSRSADVGSYRSGTRIDPELARRWAAEIRDMRTISNSPSRASGSNESLGMSKSIRDMKTEGNVAPQITDMDNVKSGSECVPEEVLPVLLLFCEAYSHFLFVLDDEDFYERQEPFTLAQQKVISGMLNTLVYHELLSTCKRSNFLLMDVAIKCVKPLYERDCRRSFCPPYLWIAPAVATQLPSRAAAGASEGNGCKSSQMAALGAILRTIPHVLSFEERVHIFREFVRTDKLLKGMEGGTVSPVPGTISIVVKRDNLFEDGLAQLNPLGPRLKSCINVSFENESVLAAADLDHGGSLKELLTDLANTAFDPEYGLFVQTATDGLLLPRAAAGNLDSELRKLKFLGQIVGKALYEGILLEHSLSPLFISKVLGRCSFLDDLSSEDSELHRKLVYLKKASEDAQDLKLNFTVKEDLFDEHWIVELQPGGADIPVTNENKLQYVNSVVNHKLNRQMKPVTAAFVRGMADLIDPEWLGLFNAKEFNRLVSGGDHDFDVDDLRIHTCYANGYSKSSLTIKIFWEVVREFEEEERSALLKFVTGCSRPPLFGFEYLQPAFTIERVVSETSAWAKIFGQDVNCLPTASTCNNTLKLPMYKRASFLKEKLQCAMKSSTRLKHP
The following text describes a protein:
Function:
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
Subcellular Localization:
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Sequence:
MSISSCSAQDGCASTAMTRTAMRQNKFATSAPASVPRLTGTEPQLGSMQGAQELLEQLKASFTSSHLIQAIGLSGRQLPLLTKDQEILPYLFNAAGVRYVQPHPNGDASQRILLLNVPASSPTPDVVLSAILKHRLELIHEFELSLGYEHLSSDQILEALLPTSIVDTDGVPTGFTIVGHIAHLNLLSVYKPFRFLVGHIILSKHIGTLRTVVNKLDSIDTQFRFFEMELLAGEADFVAQVSESDCSFQFDFRSVYWNSRLHAEHMRLIKKCRPNQVLADVMAGVGPFAVPAAKRGTWVLANDLNPSSYESLTKNAEINKVLLREGEAKPDKDGGLVATCMDGREFVRWSMLEVWKRGFAGRPMGFDGEQFDVQDDKLRQSARKMRKEQAKKNRALYAVRQAENTLEGAAESLANLSVDEPDVAATMGQVERHPERKLVDHFVMNLPAIALEFLDAFRGAYTHLATIVGKQRLLCQLELHKLDASIHRLPMIHVHCFSKDPFTPALDILTRANEALNIPRDAPYRLMAKPILPPAQTFAGLRKLCDASQSASYLSSHPNYSKYKHLESQHDFMQYVHQEWLERDAAQHTPNLSIHYVRDVAPNKQMYCLSFQCPSQVLWANTSTSQHT
The following text describes a protein:
Function:
Could be involved in the sensitivity control to chloramphenicol.
Subcellular Localization:
Periplasm.
Sequence:
MMKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTVNLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLAGYRNEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRAVEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE
The following text describes a protein:
Function:
Involved in the transport of copper, in cooperation with SWEET11 and COPT1. Contributes to the removal of copper (Cu) from xylem, and thus to the sensitivity toward bacterial pathogens such as X.oryzae pv. oryzae (Xoo).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDMGGNGMAMPPPPAPVKKARYMHMTFFWGKNTEVLFTLWPGARGGMYALAILFMFALAVLLEFRGYRVLEARLARRRAPRAAAALRTAVHAVRVGVAYLIMLALMSFNGGVFLAIVAGHAAGFLAFRAGLCGGGPAPPLEEDRKNDPVCC
The following text describes a protein:
Function:
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Subcellular Localization:
Secreted.
Sequence:
MDGAARRGVLAALLACGLLLLGAAATPTPPPAGSSPQDTCTSCGFRRPEEPGKVDGDFLEAVKRHILSRLQMRDRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPSLDGQASAGPPAHDPVSEIISFAETDDLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQDPDTSNKWNVVEKKVDLKRSGWHTFPMTEAIQALFERGERRLNLDVQCEGCEEYSVLPIYVDPGEESHRPFLVVQARLADNKHRIRKRGLECDGRTNLCCRQQFYIDFRLIGWNDWIIAPSGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
The following text describes a protein:
Function:
Component of the core of the flagella.
Subcellular Localization:
Periplasmic flagellum. Periplasm.
Sequence:
MIINHNISALRTNNVLKSVNKELDKTMEKLSTGLRINRAGDDAIGFAMSEKMRTQIRGLAQAERNVMDGVSFIQVTEGTLEQVNNILQRLRELSIQTSNGIYSNEDRKLVQLEVDQLIEEVDRIGKSAEFNHIKPLSGDHSKQSNKPIQLQVGPNQNEKLDIFIDSMNATGLQLVANGKKQALSSPASANAMIGILDTAISKVNQQRADLGAYYNRLEITSQGLQSSYVNMVAAESRVRDADMAEQIVDYTRNQILTKSGSAMLAQANMRPDQVVKLLSDRFG
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLVRLQVRNEFRLGDAKLYDEGKSDKDDSKAILDGVAVAGLVGILRQLGDLTEFAADVFHDLHEQVTATAARGRKISTRIQNIEFALPFVEKAVKGQRSHIHFAYVAGSKWHARLQDEKSQLVPSELPYFMIESYEECREPPQLYLLDKFDHHGTGACLKRYSDPSYFRRAWAASETEKAEGLQRKKVQKIQRKGSQPRIGEVQREAYISCKNSSTRFASPSIDGQSFTTEDASVHDAGLNSEFSSRSPSFGSRIREQTLDVNNSAVPGGLKDNEVSESEILCNHSDLNANGSHDNSKGRLGDSSNQGSLHRSSAVRSYSVTWDEKTEIVKPRNSVSCDVTLINTVQDSESLQVDSEPQNQNHTKAGAFSQADILLDTGKVRVSLSGANCMDEVTSEAENHADARNTLESDAEKEVECQTKWEVNPPCDFSSREMQPGNIRKQDRAAPNPSIVKLPNASQSSLKQDSSSMFMVLKPSGSSGHMPPPQETVDSSPNHEYSFGNNIHDNSEGKFDRGNRNSHLPESDIADSQIMMADKSRPKTSVACAPSIQLWANGGLFGVGASKPLFLGVMNNSSVDVTSGSRNCSSNLPNNILKTSKRINGSSTTSDAIFSFSESISRASKSAQKIDGESPVSRSLVQSNSSVNRFPARTNDLVQLNDSSKYPSSCHRNQQYDKDVKQKSQVPARSLSLGVCDMGRENHSIVTNVSSNRPVTTKNSAVVDGVPLSVVYNTKSQYHAYNQSTKGSSSGFSEPGQRFLANSLETKGSIANTDGSVPSGDKRKSEDISRLNNRMKAPSEAASLAFFGQGIKKQFDGESLERSTSSTSYLPEQSSPPLEHMKISFQPMNGLETSKMKLKVLNGSLPETSEDSIFPAFQLIQGPVDSSPDNGSESDDDTFCISCPSSEDLFSPLTDANSELWDKDERSECEDHELCDVSPRISMLNASFSGYMKLEKVNQSMMDMESGLGRYGVGNTEGTFQDVATLKLPVRGSAVSLGNQQRRHDSSSDEPASVQMKTNGHLPPPPPLPPMKWRISKPSITSGGDEAANFTDNTNYLNGLQTPTSFSPHQQDQSAPRQPCDSDLMMPYSNKTQDQQKPNKQKNLREGASNKEVDLWGELLCQIRNKSYNLRCTSMSKISLQPQATSM
The following text describes a protein:
Function:
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
Domain:
The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.
Sequence:
MSMILKEIRMNNFKSHVNSRIKFEKGIVAIIGENGSGKSSIFEAVFFALFGAGSNFNYDTIITKGKKSVYVELDFEVNGNNYKIIREYDSGRGGAKLYKNGKPYATTISAVNKAVNEILGVDRNMFLNSIYIKQGEIAKFLSLKPSEKLETVAKLLGIDEFEKCYQKMGEIVKEYEKRLERIEGELNYKENYEKELKNKMSQLEEKNKKLMEINDKLNKIKKEFEDIEKLFNEWENKKLLYEKFINKLEERKRALELKNQELKILEYDLNTVVEARETLNRHKDEYEKYKSLVDEIRKIESRLRELKSHYEDYLKLTKQLEIIKGDIEKLKEFINKSKYRDDIDNLDTLLNKIKDEIERVETIKDLLEELKNLNEEIEKIEKYKRICEECKEYYEKYLELEEKAVEYNKLTLEYITLLQEKKSIEKNINDLETRINKLLEETKNIDIESIENSLKEIEEKKKVLENLQKEKIELNKKLGEINSEIKRLKKILDELKEVEGKCPLCKTPIDENKKMELINQHKTQLNNKYTELEEINKKIREIEKDIEKLKKEIDKEENLKTLKTLYLEKQSQIEELELKLKNYKEQLDEINKKISNYVINGKPVDEILEDIKSQLNKFKNFYNQYLSAVSYLNSVDEEGIRNRIKEIENIVSGWNKEKCREELNKLREDEREINRLKDKLNELKNKEKELIEIENRRSLKFDKYKEYLGLTEKLEELKNIKDGLEEIYNICNSKILAIDNIKRKYNKEDIEIYLNNKILEVNKEINDIEERISYINQKLDEINYNEEEHKKIKELYENKRQELDNVREQKTEIETGIEYLKKDVESLKARLKEMSNLEKEKEKLTKFVEYLDKVRRIFGRNGFQAYLREKYVPLIQKYLNEAFSEFDLPYSFVELTKDFEVRVHAPNGVLTIDNLSGGEQIAVALSLRLAIANALIGNRVECIILDEPTVYLDENRRAKLAEIFRKVKSIPQMIIITHHRELEDVADVIINVKKDGNVSKVKING
The following text describes a protein:
Function:
Bifunctional aspartate kinase and homoserine dehydrogenase that catalyzes the first and the third steps toward the synthesis of lysine, methionine and threonine from aspartate.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MPVVSLAKIAASPAVTAGDFTVRVPCIYGKRLLSNRVSLRRSSVSHRVRSELQSPRVLGSVTDLSLDNSVENGHLPKGDSWAVHKFGGTCVGNSERIKDVADVVVNDGSSRKLVVVSAMAKVTDMMYDLIHRAQSRDDSYLSALDAVLEKHRATALELLDGDELASFSARLHNDINNLKAMLRAIYIAGHATESFSDFVVGHGELWSAQMLAAVVRKSGLDCTWMDARDVLVVVPNSSSQVDPDFAESEKRLEKWFSQNSAAKIIIATGFIASTPENIPTTLKRDGSDFSAAIMGALFRSHQLTIWTDVDGVYSADPRKVSDAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMKYDIPIVIRNIFNLSAPGTMICRQIEDEDGYKLDAPVKGFATIDNLALVNVEGTGMAGVPGTASAIFSAVKEVGANVIMISQASSEHSVCFAVPEKEVKAVSEALNSRFRQALAGGRLSQIEIIPNCSILAAVGQKMASTPGVSATFFNALAKANINIRAIAQGCSEFNITVVVKREDCIRALRAVHSRFYLSRTTLAVGIVGPGLIGGTLLDQIRDQAAVLKEEFKIDLRVIGITGSSKMLLSESGIDLSRWREFMKEEGESANIEKFTQYVKGNHFIPNSVIVDCTADADIASSYYDWLLRGIHVVTPNKKANSGPLDQYLKIRDLQRKSYTHYFYEATVGAGLPIISTLRGLLETGDKILRIEGIFSGTLSYLFNNFVGNRSFSDVVAEAKQAGFTEPDPRDDLSGTDVARKVTILARESGLKLDLDSLPVQSLVPKPLQACASAEEFMQKLPQFDEELSKQRQEAEAAGEVLRYVGVVDAVAKKGKVELKRYKKDHPFAQLSGADNIIAFTTKRYKEQPLIVRGPGAGAQVTAGGIFSDILRLAFYLGAPS
The following text describes a protein:
Function:
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo. Mediates mei-3/katanin targeting for degradation at the meiosis to mitosis transition via deneddylation of cul-3.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTTFFNKLFTGASSSSSAAASSGMDLGSMESLCAAINELCSEKHVSENVGELAAGIVRKNKELFEKKSNDVEAFLLHCSPNVGSAAMVAAIKGMFDTSAAKNNETGTDRAVELLNHYVDENNFVGGHLKLVPEIIFPLLRDVGLYCLEKKNKPEIGQRIIMKALGSMFPRNGSNAPNVLTSAHGVLFACALETKDYASVEPFIDLHVDEIANENCIQDQEKSDNRERDFGDVFLGRMKKGAAFGSQPVAHNPHLHPKYVLDYLYNGACILIELKRFEDALFLLEICVGMPAFSVQDQHLDSFKKYVLISLILKGKVDVTENGDKSAIRHFKTKSPEYKQFSEIRFSRSSNTHSAVESLVKSAKDRLRKDGNTEIAKYLVVEMKKKTIMSLTRMFTSIRISEIEELAFLKSRDQVTELIGQLVEEQRITVRIDGDMVFWTELSPVPSKNDVENKIRIVDHLNTLLHEKNTTMKAGSGRMRPSVMYNEDEGLSMPPTESKFFS
The following text describes a protein:
Function:
Component of the SSU processome, a pre-ribosomal particle required for the maturation of the 18S rRNA from the 35S pre-rRNA precursor.
Miscellaneous:
MISCELLANEOUS: Present with 7520 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSKTRYYLEQCIPEMDDLVEKGLFTKNEVSLIMKKRTDFEHRLNSRGSSINDYIKYINYESNVNKLRAKRCKRILQVKKTNSLSDWSIQQRIGFIYQRGTNKFPQDLKFWAMYLNYMKARGNQTSYKKIHNIYNQLLKLHPTNVDIWISCAKYEYEVHANFKSCRNIFQNGLRFNPDVPKLWYEYVKFELNFITKLINRRKVMGLINEREQELDMQNEQKNNQAPDEEKSHLQVPSTGDSMKDKLNELPEADISVLGNAETNPALRGDIALTIFDVCMKTLGKHYINKHKGYYAISDSKMNIELNKETLNYLFSESLRYIKLFDEFLDLERDYLINHVLQFWKNDMYDLSLRKDLPELYLKTVMIDITLNIRYMPVEKLDIDQLQLSVKKYFAYISKLDSASVKSLKNEYRSYLQDNYLKKMNAEDDPRYKILDLIISKL
The following text describes a protein:
Function:
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSYAETLAAKLLDAQNKVRTNPLEALQSVLEEMPVREKKANPEGKKGVEGAKLFKDAKDAAAKSVLTIVTSIEKSKLAATIKGLTDEERDTLMKFVYRGFQEEYDHMYLLTIHEEICKVSNLGPIIRSIHTRLEV
The following text describes a protein:
Function:
Could be an iron transport multicopper oxidase, which is required for Fe(2+) high affinity uptake. May be required to oxidize Fe(2+) and release it from the transporter. Essential component of copper-dependent iron transport (By similarity). Involved in meiotic prophase and synaptonemal complex (SC) assembly.
Miscellaneous:
MISCELLANEOUS: Present with 589 molecules/cell in log phase SD medium.
Sequence:
MKVILLKPVQLPMLLLILLKFIMAAKEGKIHVLEFNASSEYTLDKRRVISINGYSATFGPEIRVKSGDTLNLKLTNWICSEEEASKDSDVWKDYCSTALHFHGVVPLANEFDGIPGLTQPTIGYGESYWYNFTIDQSTCGTFWYHSHSSVQYGDGMRGVLIVECDDYDNHVANTINSVRDIETLDDGVVTMKKDKHTKELTDYEVQERIITLSDWYTNWNLDILNDKVLSSTGGTDPKFDGSLINGKSSDGETIKIGFNTEYLLLRIVNSGMSGTQVFHLDGFQLIVLEADGIMIKPFIVQTINLAVGQRYTILVKLKSDTSFIRMINGCNKMMGYITKQWWFYKEGAHLDLPKNPNDVSIEHLPGFTKAELYRDIEPTQEENKKLRTKADPVAVFEFDYAYYKDESTKQKYGTGMYKVNERTFSEYVKDPVRFGFNETYDIVINSLDHMRHPWHMHGHHFQIISLGNKGDGPFHKDVQEGKAWSRYQNDLRHLARTGKAPMVRDSINIAGNSYAVLRINTEMPGKWLLHCHVEWHMMKGLGIVFEVPTTTEDSTKQATTAVLSYPTKEPDPNTVVHTAALEQNKSKVIAVYILIMCAVDAIFYWLLM
The following text describes a protein:
Function:
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
Subcellular Localization:
Cytoplasm.
Sequence:
MRIPLLAPDNYAFPDPAYALARCDGLVGVSGDLDAGRLLEAYRNGVFPWFSRDGWFFWYAVGPRAVVFPDRLHIPRSLAKTLRNGSYRVAVNGCFAEVVAHCAAAARPNQDGTWIAPEFQTAYLKLHEMGYAHSFECHYPDESGETRLAGGFYGVQIGRVFYGESMFALQPDASKIAFACAVPFLADLGVELIDCQQDTEHMRRFGSELLPFADFAERLRMLNAVPLKEEIGRREVACKGL