lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Upon overexpression shows increased adherence to polyvinyl chloride (PVC) plates, increased mature biofilm formation.
Sequence:
MGIKQHNGNTKADRLAELKIRSPSIQLIKFGAIGLNAIIFSPLLIAADTGSQYGTNITINDGDRITGDTADPSGNLYGVMTPAGNTPGNINLGNDVTVNVNDASGYAKGIIIQGKNSSLTANRLTVDVVGQTSAIGINLIGDYTHADLGTGSTIKSNDDGIIIGHSSTLTATQFTIENSNGIGLTINDYGTSVDLGSGSKITTDGSTGVYIGGLNGNNANGAARFTATDLTIDVQGYSAMGINVQKNSVVDLGTNSTIKTNGDNAHGLWSFGQVSANALTVDVTGAAANGVEVRGGTTTIGADSHISSAQGGGLVTSGSDAIINFTGTAAQRNSIFSGGSYGASAQTATAVVNMQNTDITVDRNGSLALGLWALSGGRITGDSLAITGAAGARGIYAMTNSQIDLTSDLVIDMSTPDQMAIATQHDDGYAASRINASGRMLINGSVLSKGGLINLDMHPGSVWTGSSLSDNVNGGKLDVAMNNSVWNVTSNSNLDTLALSHSTVDFASHGSTAGTFATLNVENLSGNSTFIMRADVVGEGNGVNNKGDLLNISGSSAGNHVLAIRNQGSEATTGNEVLTVVKTTDGAASFSASSQVELGGYLYDVRKNGTNWELYASGTVPEPTPNPEPTPAPAQPPIVNPDPTPEPAPTPKPTTTADAGGNYLNVGYLLNYVENRTLMQRMGDLRNQSKDGNIWLRSYGGSLDSFASGKLSGFDMGYSGIQFGGDKRLSDVMPLYVGLYIGSTHASPDYSGGDGTARSDYMGMYASYMAQNGFYSDLVIKASRQKNSFHVLDSQNNGVNANGTANGMSISLEAGQRFNLSPTGYGFYIEPQTQLTYSHQNEMTMKASNGLNIHLNHYESLLGRASMILGYDITAGNSQLNVYVKTGAIREFSGDTEYLLNNSREKYSFKGNGWNNGVGVSAQYNKQHTFYLEADYTQGNLFDQKQVNGGYRFSF
The following text describes a protein:
Function:
Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer-coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex.
Miscellaneous:
MISCELLANEOUS: Present with 6020 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein.
Sequence:
MNGIDDLLNINDRIKQVQNERNELASKLQNLKQSLASNDTEVALSEVIAQDIIEVGASVEGLEQLRAKYGDLQILNKLEKVAVQQTQMQAGVDKLDSFERQLDELAEQPPDQFTLDDVKALHSKLTSVFATVPQINNIDSQYAAYNKLKSKVTGKYNDVIIQRLATNWSNTFDQKLLEAQWDTQKFASTSVGLVKCLRENSTKLYQLSLLYLPLEEETQNGDSERPLSRSNNNQEPVLWNFKSLANNFNVRFTYHFHATSSSSKIETYFQFLNDYLAENLYKCINIFHDDCNGLTKPVIHEQFINYVLQPIRDKVRSTLFQNDLKTLIVLISQILATDKNLLNSFHYHGLGLVSLISDEVWEKWINYEVEMANRQFINITKNPEDFPKSSQNFVKLINKIYDYLEPFYDLDFDLLVRYKLMTCSLIFMNLTSSYLDYILTVDSLNETRTKEQELYQTMAKLQHVNFVYRKIKSLSSNFIFIQLTDIVNSTESKKYNSLFQNVENDYEKAMSTDMQNSIVHRIQKLLKETLRNYFKISTWSTLEMSVDENIGPSSVPSAELVNSINVLRRLINKLDSMDIPLAISLKVKNELLNVIVNYFTESILKLNKFNQNGLNQFLHDFKSLSSILSLPSHATNYKCMSLHELVKILKLKYDPNNQQFLNPEYIKTGNFTSLKEAYSIKYLKDTKIQDALYRIIYGNIL
The following text describes a protein:
Function:
This is an intracellular thiol proteinase inhibitor.
Subcellular Localization:
Cytoplasm.
Sequence:
MGEQQASVSLLCQFPVTSSIPLLTTVILLRVVLPFKWLGCYLVKPLLEEKTNEKYEKFQAVDYKVQVVAGKNYFIKMDVGHIKVFQGLSGEDDLELSGYHTNKTKNDELTSF
The following text describes a protein:
Function:
Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver.
Sequence:
MYTLSAGIWEKFFKKKDYYVVIVGLDNSGKTTFLEQTKSHFVKDYGVLNPSKITATVGLNTGKVELNNTCLHFWDLGGQESLRELWATYYDDANALIFVVDATRSDLFPTVASQFKEVMSNEIVQNLPVLVAVNKSEMEGSAAAAEVRMLLEDDNHRSDLAVLPVSALEGTNIERCVHWIVRSLASQPLYL
The following text describes a protein:
Function:
SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Golgi apparatus, cis-Golgi network membrane. Melanosome.
Sequence:
MVLFAMISRVSDGMAMSASTDLDMHFELKESKKQAKTLARKANQFPIKCWMRSGNHNIYFIKAVGVCFLAVCEMTYPTVLAFCFLDEIQREFMVTFQSQDVQRAKRPYSFIEFDAFIQKTKQRYNNTRTLTTRINVSEMSEELQNSPPYNINSTELG
The following text describes a protein:
Function:
As a component of the decapping complex, involved in the degradation of mRNAs. Promotes P-body formation. Translational repressor.
Subcellular Localization:
Cytoplasm, P-body.
Sequence:
MATTEASQSADSYVGSFISLISKSEIRYEGVLFRINPHESSIGLKNVRSFGTEGRKKDGPQVLPSDKVYDYIYFRGSDIKDLQVLSSLSVQSVAAIPDDPAIIQSHYQHPAASSSLPHSSTSSMTSFSSNSQLALPSSNYQGSVPQYHPVGHMVSWGSSTPPTVNSNEHTVPMYWQGLNGPSGGYSYLHPSLLRPPPGLLASPGTQQMEHSTVDASIPSGATHLPEIPHLLLPTSSASSLNSTLLPSSSASSQNSILFPPSSASPQNSTMQPPSSASSQNPTVLPPSSASTLNSTFVSISSSALHSKLPIVHAASLVSNEASNYTAYFDPNAPGLTLSSNLSLASSLTSSVDTNNIALQFGEKSKSTLGSTSSYPNMPTPTPPIVGTSGSNQLEVPTPSLVTPGQLLQSAPTSPPRILSSSLPLQTAQKDIEVVQTSTLEPLSTDADEAQAPMLPTASVSSGKMNEASLDSQHHDKGLVRGRRNGPHVATSHTHRIIRGYVEERENNSNRVTLQSHHTNKVHVRGRRNGLYGTASHFQPSNRSHTGGMEKMNGTAPRPYYGSRGRAQGRTNGISRSVTEYPTDFDFEAMNEKFNKEEVWNQLGKSSKGISEDNGDADDSQEDDRQHEDAEGLLKADIKPVYVKDEFFDSLSSNTFDHKPKKGRSKFSEQKKLDAETFGGFHINRGGHGGRRAGHGGWSRGSRYGRGYEHGGRGQGRAVWSRVT
The following text describes a protein:
Function:
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MKTAALLLSALSMASAFAPASVSKRTTSLNACISRETVLSEPDTVEFGQKWDPLGLSDLGSDETIAWFRHSEIKHGRVAMAAFVGWWAVGAGWRLPGELSYGLDFASIPSKGLDAWEAVPGWGKVQMLLFAGLIEFHDEIFFSKRGTHYMKGGIPGKNMVPGLYDPLGFSKGRSEEAKARGRASEIKNGRLAMIGVAGMYAAATIDGSVPLQPPC
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MKIIKKDKEEIITNFEVLQLLKHKRRIEEQVLLNEFVNNVIRYLETTPASKQTIESVKECKKSVTKLADTSGCKILTGEMLQILNIAPSSEVEVHLVIEDCEDRIDAKEVLKEIKNSLGEEAVIRDEDNL
The following text describes a protein:
Function:
Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor.
Sequence:
MNASAASLNDSQVVVVAAEGAAAAATAAGGPDTGEWGPPAAAALGAGGGANGSLELSSQLSAGPPGLLLPAVNPWDVLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYLVPSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGIMLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSHEDPAVYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLLCGCFQSKVPFRSRSPSEV
The following text describes a protein:
Function:
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MQSIKEGYAFFILYLSQILWALYLIWAFIFDDILILLYFPFPSKYWAAVIPCAIIFTCFCFFLFTIIYSYVQTEPPHSMDLVKDKYSTFENLITEHSMNCMNDISIEQINKLFYDTSLYFD
The following text describes a protein:
Function:
Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
Subcellular Localization:
Cytoplasm.
Sequence:
MLRVIGLGAVGSLFTYFLNRAGVVPEVVQRRRCGEFLFCVEGDCEKLKFREGGAADDVGYTIVAVKAYDSRSVVPHLKGVAVVAQNGIGGYEEIKEAYPNSVPAVVTYGVYREGCRAELRGVGEIYLPSAVSTLAELLERGGGRVRLVEDIEPYRWLKLAVNAAINAITALLQAPNGVIISSPYAQTLALEVAQEVLNVATALGVKMPRNPVEEVLRVASATAKNLSSTARDVAACAKTEIDYINGAVVKYGEALGVATPVNKALFNLIKARESLCNSG
The following text describes a protein:
Function:
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDISGPEVWYNNLPNVTKYVITLIFLVTLLITCNLLNVVYILLDWNLIYYKYHIWRIFLNFLYVGKFSLSWVFFMSLFAQFSSSLEKNGIFTSPGSYLYFITIQCTFLSLISILFYWPRGYPFLGNSLLFAIIYYWSRREAWSHVSIYFFTVKGYQLPFALIFLHLIMGQSLWVDIMGLLSGHVYYFFREILPREGGPNLLDKTPKIFDKIMLKLQEFRLNNGIRNNFSRYGYTNINNSRGTNNNNGTNRRVFIGRGVRLGDS
The following text describes a protein:
Function:
Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MKYFVAVRPFSFVASAFPVTVGAMLAEEFSLIRYILSLIASIFLHAGVNTTNDYFDYKKGVDTKDSLGSSGLLVSGKITPREELLLSVFCYAVSVVLGLVLIKISGPALLWLGLTGLVLGYAYTGHPFYLKYKSLGMFLVFILMGPLMVLGAYYVQTGRFSLEALLVSIPVGIATDLILLANEIRDSEFDRRSGIKTLPILIGDRAASFLYAVLTGLIYVFIVILVSTGVFRVISLVSLVSLPLYIRVIKQLFQKSAGRKNAREIADVDKMSALAEMILFVSMILGLLR
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MSRYLTRQRKRRVYTWNGKPTLIDRKLQFFYYDGFFMYAEGTSEASSIKLGQYILIEGDDDDNPFIAKLLKLYGSGPRERENKRAEVQWFARFSEVPSNKRKMLGRAPHPQEIFLYDVTNCDCEIDVETILGAVEVRHVEPQAPFPVEQSNGTLYVKLSWNGKAFRAVTAEQVGQGSGASLAPAPRGSLPTPDVAVMKRALAGAVSVGVPASSQAESHHSSSKYSQSKGLSARRQAKCSSTPGVRKKLQLSSPGKSAGARLTRDDVLEELLHTEIENQKSELTSKVLATPPRPLAITVRLSPIRSVAITSPAVRICPLQGAQDPAGSTRPDRNQESAKDTSGVSPLDGEVDKVRVSTRSSKTPCKKEDTPRKSAVRPQKNRLVFYCSDRPAVKEDNCLWFSREEAKDNNADTEQTAMTPRSKRKSAMLVSSRIRKQLNLLNGVQDAHSDVDDDEDEGFIPSKKDLESSSEEEAEADSEGDSIAEKKSRRAAGACTPRARRKASTPSRTPRKTPSKKIAPSTPRTPHNATPSIPSRSLPAKKPGNILEEARARLHVSSVPESLPCREQEFQDIYSFVESKVIDGTGGCMYISGVPGTGKTATVHEVMRCLLHAADQDEIPPFNFIEINGMKMTDPHQAYVQILQKLTDQKATADHAASLLEKRFSTPAPKRETTVLLVDELDLLWTRKQNVMYNLFDWPTRRHAKLVVLAIANTMDLPERIMINRVASRLGLTRLSFQPYTFKQLQQIITSRLNRVRAFEEDALQLVSRKVAALSGDARRCLDICRRATEICEFSNNRNSSSGLVGMSHVMEALDEMFSSPYITAIRCASLQEQLFLRAVIAEFRRLGLEEATFQQVFQQHRALCRVEGLQPVSLSEGLAACLRLGACRLLLLEPSRCDLLLRVRLNVSQDDVLYALKED
The following text describes a protein:
Function:
Catalyzes the fourth and sixth steps in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. The C-terminus mediates the fourth step of the pathway and catalyzes the removal of UDP from C-1 of UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose. The N-terminal part mediates the last step of the pathway by mediating activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid.
Miscellaneous:
MISCELLANEOUS: In publications, PseF (HP_0326A) and PseG (HP_0326B) are separated into 2 separate ORFs. However, these 2 enzymes are fused into a single protein in strain ATCC 700392 / 26695.
Sequence:
MRAIAIVLARSSSKRIKNKNIIDFFNKPMLAYPIEVALNSKLFEKVFISSDSMEYVNLAKNYGASFLNLRPKILADDRATTLEVMAYHMEELELKDEDIACCLYGASALLQEKHLKNAFETLNKNQNTDYVFTCSPFSASPYRSFSLENGVQMAFKEHSNTRTQDLKTLYHDAGLLYMGKAQAFKEMRPIFSQNSIALELSPLEVQDIAHFRRFRISQAQIQPFEKRMPVKILCDCFLTSGLGHVRRCEKILSFIEKLGVEASLYLHKQNNISAFLEGVGGNDFLITDSYCLNSKDFYLLKEKAKSLMVIEDTEHAKGFYPKNTKILNFTLNALKHYHHLSKDYQYYLGVGFYPVDARFIYDRPINTENKEVLITLGGSEQKTLKEIVKILENKNVNLHIISPYTPKNPPKNTHYYSPLNPLEFSSLMKSCACAISAAGQTLYELALSQTPSLILPIASNQIIQSKEFESLGIFKQTSLKTLAKDFENLQIQKNQAWAKNLVFGDKLEGALREFLEI
The following text describes a protein:
Function:
Involved in the assembly of cytochrome c oxidase.
Subcellular Localization:
Mitochondrion.
Sequence:
MSTASKLCIVGAGVFSVYMVYFVHNNQIIEREKMSAGVQKDDERKRIKKERFEDLKRQQELRKFYESQLPVEEDEKGLRQTTQTTVND
The following text describes a protein:
Function:
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
Sequence:
MDYFTLFGLPARYLIDGNQLTTRYQELQRQFHPDRFATQPERERLASMQQAATINDAYQTLKHPLKRAEYMLSLQGFDLGNEQHTMRDTAFLMEQLELREELDAIERKPDAETLLAEFSRRVAQMTTTRTQQMVEQLDAQLWVQAADTVRKLRFLDKLQQQVEQLEERLFDDFA
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAKLVHNVQKKQHRERSQTQSRARYGLLEKKKDYKLRAADYHKKQAALKALKEKAKLHNPDEYYHAMTRKKTDDKGILISERDNEVLSVEQAKLLKTQDVNYIRTMRLNELKKIEKEKEGKLFGASGKHTVFVDSIEEQESFNPEEFFDTDAALLDNRENRLRMNQLYDNSGLLTSNDLDIDTKNKLDLKKLKQYKLLQRRLKKEKELKEVESIMSKNLEKMKKGNKKKVVDSNGKVHFKWKNERKR
The following text describes a protein:
Function:
Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
Subcellular Localization:
Nucleus.
Sequence:
MSNRDSANPPGFNDAVPLAICYIDSSTSSHDEYLTLLQSKVSAPDKNFRDETVDGAPFLAGDAISKGHRYSPPVRSDRASAQGLLQQHLEKSSTLENLKRYSSTLLGRQNDAVIDEPFAPFRPPPRVTLSESRRDRWLQGLSDPMVPLSSLIKTIPHGLWGEDILRMLVKFRVPFTRAIWFIRCAGVNEARSFLRKVQTTDITEWVKNWTDVAAGFLISFISSFLNADIYSFADDYTYLLKLFGRLLAEELVSPKHFLLRIVSFSGDSSLKSFSLHFFALQFFSTSLIQYTHICRKCVITILQSYQQLIVDQPANLLKFSLLSKKVSHFLFTLAQKNIESFFFPTEWDKLKPTIILLWKDFPNYSTLLSIMQERNSKAMYMYKPVTSSIRFLQIISCLSFPVGWRTLAKDLFKLLPVYTGVPLLLHWCINCRSIFSGDRNFIVSSIFDNANFDRNLIVDLTLSFVLKLHPLEYNECVAAAQLLDHLAACGYFFFSKYIARLASLGYLRESMLNSSFMDDQRKILVQLPILRMSQQLKNKIYYILSKGNYFVDWSICDEYVKRFKEDHFSFMFKKEENYAIITLSLVKIASTPMSKLYEDYLVMLFAFHYSMFQVMTKLIADNLVHFSFQSCACQTLFFICSVVPKTESQKLLLNEMGKLFQVELNFSYDSPDVNLLIEQFYEITSYESNYDDAFVEYKDATVANRKDFIEFLFHNITVSSKHTAVIFTSDLLMVLKIALNHPPYFDDLATTTFSSLLKRDECTILSFFKILQFYGCKLLSVDQIWAVVSDVYEAQDNNTTLKQFFNYLLDESTWPEGYLEERHWRSILCKEARKHDSGLKLFKLGIKLCTRNEQIMKTIWSFIHVHDCNVISEVIPDQRFLRTLTEHFMIDLRQLDIVTCLKKALVTLDEFSAPLYATWLTTLDDDELSELTDDVVQKKVLESLDNYKSGIWKLVLSGLPNCKTVFEHLLLFSLEERLDLPAAFLQDLIGASAYVMEQVPDSWFLEKLPCPLTQSLQSFSHLSNHIEVLDSTRQSRLTFLCHLILHMHGFVELTDQLATLESLTIRKCIYRNQELLDLLLFSIHLVKPNVETNDEVCNTLKAWENIESRPYTIDFPEALQQYSPRIVLYEPTFW
The following text describes a protein:
Function:
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
Subcellular Localization:
Cytoplasm.
Sequence:
MSTHVTFDYSKALSFIGEHEITYLRDAVKVTHHAIHEKTGAGNDFLGWVDLPLQYDKEEFARIQKCAEKIKNDSDILLVVGIGGSYLGARAAIEMLNHSFYNTLSKEQRKTPQVLFVGQNISSTYMKDLMDVLEGKDFSINVISKSGTTTEPALAFRIFRKLLEEKYGKEEARKRIYATTDKARGALKTLADNEGYETFVIPDDVGGRFSVLTPVGLLPIAVSGLNIEEMMKGAAAGHDDFGTSELEENPAYQYAVVRNALYNKGKTIEMLVNYEPALQYFAEWWKQLFGESEGKDQKGIFPSSANFSTDLHSLGQYVQEGRRDLFETVLKVGKSTHELTIESEENDLDGLNYLAGETVDFVNTKAYEGTLLAHSDGGVPNLIVNIPELNEYTFGYLVYFFEKACAMSGYLLGVNPFDQPGVEAYKKNMFALLGKPGFEELKAELEERLK
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MYLKRNIINMQRSFSRQFHISVRNSIQSSKPLSNSTPLKGCSVGTILIRSPILTRQPSEFEKSIYKYNAELWNELSDPLPAEFYFKKGSVGEKDWQERQKTLKGKESPFETIFGKERKEMESNKLLDSATHLQSRVTEADTKNDERSTLRSLDKSLYLLVKKSKSSGWQFPNTPVTSSEKALHLLCQDLLKNILDENSLTWLVARHPLALLKTEQEKTFLLRARLLNGLDVPNLQNVYDWVWCTYDELKNKLSPSSWDSVKNILSDRL
The following text describes a protein:
Function:
May play a role in TRPCs intracellular trafficking.
Subcellular Localization:
Golgi apparatus membrane; Single-pass membrane protein.
Sequence:
MLNKSGESRYPALFPVLGGSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV
The following text describes a protein:
Function:
A transpeptidase that forms peptide cross-links between adjacent glycan strands in cell wall peptidoglycan (PG). Part of the elongasome machinery that synthesizes peripheral PG.
Miscellaneous:
MISCELLANEOUS: Structures 2WAD and 2WAE are from strain 5204, a clinical, drug-resistant strain with 58 mutations in compared to strain R6.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Note=Localizes to the midcell division sites, colocalizes with StkP.
Domain:
Comparison of drug-sensitive and drug-resistant protein structures shows the active site is highly flexible.
Sequence:
MRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETAKKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNNAVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFNSELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSVVKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSNTYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFVPKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGDLIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTAESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYHPMN
The following text describes a protein:
Function:
Plays a role in L-cysteine detoxification. May transport both D- and L-serine (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
The following text describes a protein:
Function:
Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP-2A (pbpA) in determining the rod shape of the cell during vegetative growth and spore outgrowth.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MTEIGREPKKKSKGNRAIRMNLFFLAVFVLFTALIFKLGVVQIVEGEQHEEDAEKSNAKTAYYPAPRGKMYDRNQKVAVDNQSVPEIVYVSTSSTKTEDKIKTAKRLASFIHIDTEFLKERDLRDYWIAAHPKKAAALLKESESNLKGDQAYKLQIERVPDQELKAIQQDDEEMETAAIYTRFSSGNAYEPQIVKAMNPNKSNSNGKNGALLDEKKNSSQRPKNDLTYDEISIVSEHLEELPGIDIVNDWTRKYPYDKTLYSVFGGVTTPDQGLLSDRKDFYLTRGYANNDRVGKSYLEYQYEEYLNSHKEKVEYVEDNKGNVVSQKTIDKGSRGYDLQLSFDMELQAKVEKIIEEEVRNSRARGNYMLDRAFAVMMDPNNGDILSMAGKKIDLKTNKIEDYAIGAFTTQYEMGSAVKGATVLAGYQDGIPHYKYYIDAPMLLGTNLIKKSYTNMGTINELTALQKSSNVYMFNVAMHIAGVTYKPHGSLPADQNDLLKMRNYYSQFGLGVKTGIDLPQESAGMQTTPKTVGGLILDLAIGQYDTYTPLQMAQYISVIANGGYRVQPRIVTSIHKPGKKDQLGKAIEHRKPKVLNKINNSESDLKQVQTGMKLVTSSGTAKNTFTEDVSGKTGTAETFYYGTNRNWWGKKTYNLTFVGYYPSKKPKVAFSVVVPSVDDDDKINKIIAKRAIHAYAELEKKHSKK
The following text describes a protein:
Function:
Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.
Sequence:
MSSGKTFKLSNGVTIPAVGFGTFASEGASGETYRAVKKALEVGYRHLDCAWFYQNEDEVGDAVRDFLKENPSVKREDIFICTKVWNHLHRPEDVRWSIEDSLKKLKTDYVDLFLIHWPIAAEKESQDKPKIGPDGKYVILKDLTEDPKPTWQAMEKLYEDKLARSIGVSNWTIEGLEKLLKYAKVKPHVNQIEIHPFLPNEELIQYCWKNDILPEAYSPLGSQNQVPTTGERVSENKTLNEIAQKGGNTLAQVLIAWGLRRGYVVLPKSSNPARIESNFKTIELSDEDYEAVNAVAKGRHFRFVNMKDTFGYDVWPEETAKNISA
The following text describes a protein:
Function:
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates. In addition to ATP, is able to cleave other nucleotide triphosphates such as CTP, GTP and UTP, but hydrolysis of these other nucleotides is less effective in promoting proteolysis than ATP. Moreover, PAN by itself can function as a chaperone in vitro.
Subcellular Localization:
Cytoplasm.
Domain:
Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
Sequence:
MVFEEFISTELKKEKKAFTEEFKEEKEINDNSNLKNDLLKEELQEKARIAELESRILKLELEKKELERENLQLMKENEILRRELDRMRVPPLIVGTVVDKVGERKVVVKSSTGPSFLVNVSHFVNPDDLAPGKRVCLNQQTLTVVDVLPENKDYRAKAMEVDERPNVRYEDIGGLEKQMQEIREVVELPLKHPELFEKVGIEPPKGILLYGPPGTGKTLLAKAVATETNATFIRVVGSELVKKFIGEGASLVKDIFKLAKEKAPSIIFIDEIDAIAAKRTDALTGGDREVQRTLMQLLAEMDGFDARGDVKIIGATNRPDILDPAILRPGRFDRIIEVPAPDEKGRLEILKIHTRKMNLAEDVNLEEIAKMTEGCVGAELKAICTEAGMNAIRELRDYVTMDDFRKAVEKIMEKKKVKVKEPAHLDVLYR
The following text describes a protein:
Function:
Mediates the transfer of lipids between membranes at organelle contact sites.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MFESLIADFLTKTIGKYIEDLDVNSVSVSLWNGNVQLKNLQVKKDACSAFNLPVIISKGILKTLEVEVPWKSIKTDPFKIKIKGLHIISQPQTVFVFDAEQYDLKKKEHRKEIIDRFEIIQQIAETKAGGDESGVWTTLVNKIIENLELEIEDINFIYKGDENEGIIGFHLNSIVVKNSMSITDTINKVCQLNNLSIILYDELNEMNDKESEQQNEKGLNSFDLMNKTVLATIPSFQFNLSIEKTMRHKVTLGGEIQQIFFSLNKKQYSNVMHIVERMTNYTQTIKYLYCRPTVSALEQPKKWWKFAFIATRDYLREREEEKNPIRFDFCSTQRERFIELFKKVRKIPWVIPATNDEIEEYNLIENQLRNQEICYLRQIAYKIVSEEKKIYESTRGWFGFGYQVPELSEEAINQIYNAIDYKHEEYSLPPETIVFEIKTIIQKIQFKLIDEDKIVCKMKIEKMNIGFEARVIGLKLNLSFDNGEVKENKVGLGKIWTKLSDEKSFKMEFEESPIDKHCDAIISIDCAPSVINCSKGFFDSLVDFLTLPSNLNLNYVKQFAEYQLQQLYSSAASQIDIFADEPPLLDIRINLTAPVIYFYYDGKEKGMDNNIALFQLGNVKITNSQRDENYQNYDIRIDDVLIKFLDSIQDQFDSKKNIVVQKTGATLQLSTLYSSEPIPKIKLGINIDPFIAQLSKRKYDKLIAYIYLLLSFFPSDNETTINTNQTEDIDVVLVKELVKKQSELSYFIADINIPLFHVLLSRMNDITEESTMTSVKIERSIFGVNVTPSAVTINISLGQLIMDNGYNTEIPYLVTSDIQSKTIQKHLKEERGFQIGIEQPFLQCSIKVIENKVSVDVAIDTFTLIYEPQIISEIIIFSMSLTMLPESDSTTNYIYNININLSHFYTIFQSEIAVLAICYFDGLNVQLNMDSKIIDLTLKINEIDLKNTLYEKEDPRYTSIVSVGSQVFLLHYTNGTETSDILELKIGEVICNYVMNDFFKIINVIYNDQVKKAIDLTSVQKKIEEQYEYLKKTVTSSLLDIKKEPRKTTDIKIKAPTLIAYLPSGQVIVRIGAINIEDGNNGWEILFDKMKITTNINRKKDRCINDFTFSVNIPLVEEGKQPTIITEFPCADIALSPNQFKLLLDFVKTFFSSDQSNEESQSIKRIELCKLPPISKNINLSIGISIKQFEISIKEDCDIPNGVSKLSLINFIGNVDLTDNSYAMFHFTTDNLMIIDTRTKVEMEEYRNIFKKSKIDKILTVVGNYSIQYGNIQSNLDIYSSSLILTPQFITKLINTLNIMFDGNDIILVNPNDILLHPSTKVVVNCKTEENIQQSEIEESTNNFTENQSIINSKPNSNISSPHKNTIPINLNNSNKSELINSQYVKENLIHLGDDQDSFKNTFINKGLKRKSQKPSEIIKYLNEACPMEMTFAEVILVLKANYEWSYPQYVCEYICEELVKIGVLVPTIPMGRHIPNIDSSITYVTCNIPNIDTFHIDLTSFQPCRPISSAISPDQIHVFTISLHDTAIIAVQDDSPDTALLHVTIDATICHTVTQCGSTSLAELNIIDVRSCFSRGHHFDLKKGIQLSQGISLSTSIIREGWDNWFGIRGSVTVNNAELITTFSDWKLILYFINLLGKFGGETNYEIDSECSIRIDLNGFKLIVGNPLRKDPLFRMKIPSATVVYRSRNDDSILRVLGQIKVDGYNPQTREYDVMLEKTLMEFSRRSVVDCIQGSVVTRVLTNIDLGNIECILTVDLMKEMKRVFQTDFWTPKEENLDFIPIQFIDEYSAYEKDSLMVSITNCGVLKLNNKLQHFENMTLKREYTELKKCMVFTPEGEGIEVPIICEGEYVHKLRSGYLVISVIIQQDSSKIIKFSSLLAIQNDFEEELFISIQIPNPIKINKLKNNNLRGLFDTPRHRLGSNNVVKSCHSTNIEATPRPRLFSTSDKSSDKFTQQNNDVPQLKNLLNVEDNHDEESQDDIPDFIEVQASIPSKGIFYVPPQFFNGQISLCSSRLSNYKMPLKDLMTEKYVEVNSSKCILTRISTREIVGFVQTTISLAPSLIVTNLLPMPFSLKTPTSVFPVRSLSSISTFINPDSPVFITIAGYNETLIPKSGELKIFGKCKGYNSIRYFWDIGTLRIDAEEWVFNRSFIPLKFSLDKKNYIGGKIGLRNNSQPLPITRFSKPLYIGTGNSWSRALLLEKAEEVIRIIENGITYDLVVGISIIDGIARQITIRPAFMAVNDLGCELYCSVGSNYKDVIIIPPKGSIPIYGSFSISSSINVSIRCKGPWCRVPIDKDTHFQLLLLTKENGSIEEGQATTISIHYQQSVIIHFQEIQETSKYVIENDTDYSIIFKHIHSDEQTQIEPRKSQPVVFPNTSHISTIQIKSEFSINEFVTYSLDNPEVYEAKAGIHGIVYPYTWIFNGVNKLVFTDKWEKMKGDIGGLIRKEKMNTTEFNITINKLGIDLIDEDREELAYISLKDITYNKQGTLFKNKHRLFIGPIQVDSNARDCSVAVPFVSKGINICVDIVSQQNNTYKHIPHCFIQFQNMFISLETPFLNRIIHLIRLFSNPKDNKSLQIEIPKLYIEPIPYSNSQTITFETLQISPVDIILNTMLSSSSLLNIGYNSFTAPLLMIGNSLLTIKSARIHLNDFISNKLSATPERLSLFFIDFYRSQAIQQLLLAVSSMEFIGAPGVLVHSVYDGITDFITIPQKEKHSGNGIATGLAKGTESLLLHSIHGISSTAASISNTFGNLTASLTFDEDYIKERERKKKPFSASEGMAQGLGCVVNGIVDGVKGVITQPIKGAQTKGVSGFVGGVGKGLIGVVLKPTGGVVDFVSKMTEGIAEESGDIIPRSRIPRVGNKRRRIMSYNEEEAKIAWILQRKGLGDFVIYVTIDDIWVVLTETSFVMMKESGVMVSRLFQDLSIKVGPKTVTFSHFGHQLLTVSYRQGKHMPYLNEHLFKQRDKES