lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Required for the correct development of pollen.
Subcellular Localization:
Nucleus.
Sequence:
MGANSSKLEKALAEAPEDERYYGLENFGNTCYCNSVLQALYFCKPFRERLLKYGASLPGNVEENLLNCLADLFTQINSSKKKVGVISPKKFVQRLKRDNELFRGHMHQDAHEFLNYLLNCSCELLEQEAKAAGGGGGGGGGSSQPITTWVHDIFQGKLVNETRCLHCETVTSREEVFMDLSLEIDQNTSVTSCLRNFSSMEMLDRDDKFFCDHCCCLQEAKKRMLLRSVPPCLILHLKRFKYVEAQGRMRKLMYRVVFPMELKLANTTSDDPAAPDTLYSLTAVVVHVGSGPHHGHYVSLIKSGSQWMFFDDETVELITESQVQSTFGSTSDYGQNNMDHGYILFYEKAG
The following text describes a protein:
Function:
Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
Subcellular Localization:
Endomembrane system. Membrane; Multi-pass membrane protein.
Sequence:
MISVVVPTYNEAENLAELVQRLDGALREGYEIIIVDDNSPDGTAEVARGLASRYPVKVIVRERRGGLSSAVVEGARAASGRIVVVMDADLQHPPEIVPALVREAERGCLAIASRYIKGGMVVGWPLARKIVSRGAVMLARLLLPEARGVKDPVSGFFAYSRDCIAGVKPTGLYKILLDVLAQCKPACIVEVPFVFGRRTRGRSKLGRRHIFDFLRQLLVLSRWRPLKFAAVGATGIGIALMVIYALGWLPPLISTAAAIEVSLTSNYVLNRSWTFADRQTPFLAGWAKYHLATAIGNITNYLVTNGLALLGLWIYASYVLGVIAGYIANYVFSELRVFK
The following text describes a protein:
Function:
Has a very modest degradation activity against heparin sodium salt (HS) in vitro. Involved in the pathogenesis of vancomycin-resistant E.faecalis infections.
Subcellular Localization:
Secreted, cell wall; Peptidoglycan-anchor.
Sequence:
MIKKIIVVVAFMLTGFSLTAMSASAEEITDLFLQKEVTYSGVEGGKIGENWKYPQFVGEKAVDGDETTRWSADKQDEQWLIVDLGEVKNIGELVLQLHAESPVYEILVSTDGESYQSIFKEENGKGGQPTKKYIDGNNVQARFVKYQQMKMWQHTNKQFYSSSIISFEAYEKKRLPEAIKLLTENLTISEKRKQQLAFEVSPAGVDITEDQIEWSSSDPTIVTVDQTGNLTAVKSGEAKVTVKIKGTEISDTIPVTVVAENKQYAEMRAKWKMRLLGTTQYDNDADVQQYRAQIATESLALWQTLNQAADREYLWERKPSDTVSADYTTQFTNIKKLALGYYEPSSELFEKPEVYDAIVKGIEFMIDTKKYNGTYYTGNWWDWQIGSAQPLTDTLILLHDDLLNTDAEKLNKFTAPLMLYAKDPNIQWPIYRATGANLTDISITVLGTGLLLEDNQRLVQVQEAVPSVLKSVSSGDGLYPDGSLIQHGYFPYNGSYGNELLKGFGRIQTILQGSDWEMNDPNISNLFNVVDKGYLQLMVNGKMPSMVSGRSISRAPETNPFTTEFESGKETIANLTLIAKFAPENLRNDIYTSIQTWLQQSGSYYHFFKKPRDFEALIDLKNVVNSASPAQATPMQSLNVYGSMDRVLQKNNEYAVGISMYSQRVGNYEFGNTENKKGWHTADGMLYLYNQDFAQFDEGYWATIDPYRLPGTTVDTRELANGAYTGKRSPQSWVGGSNNGQVASIGMFLDKSNEGMNLVAKKSWFLLDGQIINLGSGITGTTDASIETILDNRMIHPQEVKLNQGSDKDNSWISLSAANPLNNIGYVFPNSMNTLDVQIEERSGRYGDINEYFVNDKTYTNTFAKISKNYGKTVENGTYEYLTVVGKTNEEIAALSKNKGYTVLENTANLQAIEAGNYVMMNTWNNDQEIAGLYAYDPMSVISEKIDNGVYRLTLANPLQNNASVSIEFDKGILEVVAADPEISVDQNIITLNSAGLNGSSRSIIVKTTPEVTKEALEKLIQEQKEHQEKDYTASSWKVYSEALKQAQTVADQTTATQAEVDQAETELRSAVKQLVKVPTKEVDKTNLLKIIKENEKHQEKDYTASSWKVYSEALKQAQTVADQTTATQAEVDQAEAKLRSAVKQLVKVPTKEVDKTNLLKIIKENEKHQEKDYTASSWKVYSEALKQAQTVADQTTATQAEVDQAETELRSAVKQLVKVPTKEVDKTNLLKIIKENEKHQEKDYTASSWKVYSEALKQAQTVADQTTATQAEVDQAEAKLRSAVKRLTLKNSGENKKEQKNGGNNGHLNTSTGVDQTGTKQVKPSSQGGFRKASQFLPSTGEKKSIALVIIGLLVIASGCLLVFRKSKSKK
The following text describes a protein:
Function:
Probable malonate and methylmalonate semialdehyde dehydrogenase involved in the catabolism of valine, thymine, and compounds catabolized by way of beta-alanine, including uracil and cytidine.
Sequence:
MFINGQFVESKTTEWVDLKNPATNELITRVPKCTNAEMHEAVRSAKEAFRTWSQTSILTRQQSMFKLQQLIKENMKRLAANVTEEQGKTLADAEGDVLRGLQVVEHACGVTSLQLGETLPSITKDMDTMSYRIPLGVTAGITPFNFPAMIPLWMFPLALVCGNTMVLKPSERDPGCTMMLMELLKQTGVPDGVVNVIHGTHDAVKFICDHPDIRAISFVGSDQAAKNWIPELVERARKLKVNAGHEPGADLGPVISPEAKERICDLVESGVQEGAKLLLDGRGIVVPGYEKGNFVGPTVLADVTPQMRCYQEEIFGPVLLTLSVDSMDDAIALINSNPYGNGTAIFTTNGATARKYTQEIDVGQVGVNVPIPVPLPMFSFTGSRGSFLGDANFYGKAVRATVLVDLVD
The following text describes a protein:
Function:
Probable organic anion transporter which may serve as a transporter for some non-steroidal anti-inflammatory drugs (NSAIDs) as well as other organic anions across the luminal membranes of renal proximal tubules at the final excretion step into the urine.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein.
Sequence:
MADNRSSSEEASSSRVIRVVFLALLLDLLGFTLILPLLPSILDHYSQTGDNVYQSLQSVVDWFRGAVGAPMETKYNSVLFGGLIGSLYSLLQFLSSPITGALSDDYGRKPLLLLTTIGLMASYVLWAFSHSFTVFLLSRIVGGICKGNVSLCTAIVADLPCPKARNKGMAMIGVAFSLGFTLGPLMGAYFALRLKDAEVFYQGPAMLAVLFSLADLLFIFFMLPETLQKGASESSGLQQQSGDLLHPVALFNFTAVRRTENPPSEQKMQNLKVLGLVYFTYLFLFSGLEFTLSFLTHQRFQFSSMQQGKMFFFIGITMAVIQGGYARRIRPGHQIQSVSMAIITLIPAFLLVGIAWNLTLLYSGLFLYSFAAAIVVPCLSTQVSGHGSASQKGTVMGILRSLGALARALGPIVASSVYWLAGAELCLIISSVFFIVPLILLSRLKGQKEE
The following text describes a protein:
Function:
Involved in the export and assembly of PsaA (pH 6) fimbrial subunits across the outer membrane.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MKKLIVQFTTITLLMSTSFLVGAQRYSFDPNLLVDGNNNTDTSLFEQGNELPGTYLVDIILNGNKVDSTNVTFHSEKSPSGEPFLQSCLTKEQLSRYGVDVDAYPELSPALKNSQTNPCVNLAAIPQASEEFQFYNMQLVLSIPQAALRPEGEVPIERWDDGITAFLLNYMANISETQFRQNGGYRRSQYIQLYPGLNLGAWRVRNATNWSQSGDRGGKWQSAYTYATRGIYRLKSRVTLGESYTPGDFFDSIPFRGVMLGDDPNMQPSNQRDFIPVVRGIARSQAQVEIRQNGYLIYSTVVPPGPFELSDVIPSKSGSDLHVRVLESNGASQAFIVPYEVPAIALRKGHLRYNLVAGQYRPANADVETPPVAQATVAYGLPWNLTAFIGEQWSRHYQATSAGLGGLLGEYGALSSSITQATSQYHHQQPVKGQAWEVRYNKTLQASDTSFSLVNSQYSTNGFSTLSDVLQSYRQSGSGDNRDKIDENSRSRDLRNQISAVIGQSLGKFGYLNLNWSRQVYRGPIPAKNSLGIHYNLNVGNSFWALSWVQNANENKNDRILSLSVSIPLGGHHDTYASYRMTSSNGSNDHEIGMYGQAFDSRLSWSVRQAEHYGQPNSGHNSGSLRLGWQGSYGNIAGNYYYTPSIRQLSADVSGGAIIHRHGLTLGPQINGTSVLVEVPGVGGVTTTEDRRLKTDFRGYSIVSGLSPYQEHDIVLETADLPPDAEVAKTDTKVLPTEGAIVRASFSPQIGAKALMTITRANGQTIPFGAMASLVNQSANAAIVDEGGKAYLTGLPETGQLLVQWGKDAGQQCRVDYQLSPAEKGDTGLYMLSGVCH
The following text describes a protein:
Function:
Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles. Guides the V-type ATPase into specialized subcellular compartments, such as neuroendocrine regulated secretory vesicles or the ruffled border of the osteoclast, thereby regulating its activity. Involved in membrane trafficking and Ca(2+)-dependent membrane fusion. May play a role in the assembly of the V-type ATPase complex. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. In islets of Langerhans cells, may regulate the acidification of dense-core secretory granules.
Subcellular Localization:
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane.
Sequence:
MGRKLLFSFSLLFLCMVFSVSLDQILARKNVGSQASSSKEAIVPNGQRNSGEVKPVQNLTTVPITQTFNYNLSKAHWSTFSHHNPVKFSRDGIPCILFWTKRITVKFKNQTWLDLTDEALGQNTTVDTGNSNCSEENAVIKQMRKSKHRLWRTVRLSLKFGDAENPKDIDIRFTLSNYIKLSSQSWFSLHRVEIIFNNSVQATFNATGIYALSTYSYHCQRVSSLRRNDALLLLSSSDDVTSLWEVTFIDFQIQGFSIKGAQFSQARDCSSSFSPAVLIGLAMSLILLLVLAYALHMLIYLRYLDHHYEFITSPAHFPSLRALDIGEEKELLGSQGAECYELRNQQICKIYI
The following text describes a protein:
Function:
Deubiquitinating enzyme that specifically hydrolyzes 'Lys-63'-linked polyubiquitin to monoubiquitin. Required for the stability and translation of a subset mRNAs with a high abundance of rare codons by mediating deubiquitination of 40S ribosomal protein RPS10/eS10, thereby antagonizing ZNF598-mediated 40S ubiquitination. The abundance of rare codons in mRNAs can limit the translation rate and can lead to ribosome collisions that trigger activation of ribosome quality control (RQC) pathway by ZNF598. OTUD1-mediated deubiquitination prevents activation of the RQC and subsequent dissociation of ribosomes and stimulates formation of polysomes and translation.
Sequence:
MTGQKPRNHISHLITVTSYYPSFLKTLSLACFTLFILRVEGMFTARPSIITTEFVKPQPIARVSDNFLHADNSVETIGIPVRDDKQNMIRYPHLPGETGIHLDRVDKPPPIEYPVNPVPKPLADPKVGSPNLPQKTKQKWTWRRFKDHIKTKFKALIAKLKKLFTWRKKITPLDGKLEKPTSLRPPGPKANEAAQGQPTEVNPLVQGPPIKANAVAQAQPIMTNEVAPATHGPALYPSQDDGYLDHSFSSSSSSDSSYPGSSRWGSFSGTSGSWSPPRQPVAPRLSGSDDALHRLNNLKLITKLPESTTLVPIEHLPGYAKTQGFIEPDGNCMFRAFSYLLYQNQDSHWEIREKIVAYLKKNWYEFAESMVGDEDINIRAQQYIQRLEGGAWGDHIEETIFGRLYNRNIVVVSNLESAHAQVRQPDLSSNEFDALFLRGQHYELLVKDPHWKPASAYPNPSRSQTI
The following text describes a protein:
Function:
Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (LPS). By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria.
Subcellular Localization:
Secreted. Cytoplasmic vesicle. Note=Detected in urine.
Sequence:
MKFPWKVFKTTLLLLLLSHSLASVPSEDQPGDSYSHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQPQCHLYPLPQEAWESALEKARQVLRRSSTMKYPRSGRNICSLPFLTKICQKIELSIKKAVPFKDIDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSSLPQEAALPITNTLFPPPPPYFQAFTDEAIERYETLTGKSLFVNDEKGKTKGKEKKSDDRDMSVDIRIQDLTEEEQNEKLELEGKLEKPRADWVNEDGRWMCFGTMYTTEPIIPTAQSIGLPPFIDPAVEPQESLPPLLHSFLHTLLLLLDTLTMTARTPNELAAAGWASEGDQYIQHLTNLSANMMVASNQLRSAQSEATLVLLMEKELEERRKQTEKLRSKCKEIASGIRALKGL
The following text describes a protein:
Function:
Pseudouridine synthase that catalyzes pseudouridylation of mRNAs.
Sequence:
MQNSPAPCAWYLPWSLAAQQHQQKMLQMQSPFLDKMGATSVGGIFAGQPQMQQQLSPNTAAAPPANYQQPALHPSAAPGAPHFHMGSPYSHLAPQLLNAGQLNQNALMHSAMFSSLPLGAYYAPAAGAGHSAFGGVPLTTAAQQSLLAATGGATAGHLANQQTTAQVPVQVPVQMAQRTAPAACSMVQPLNCLPHQELNHLSSINLNLLRSPAPPLPAIQVLPSAEVPINKKTTSPRDSENLKIKVPEKRKTDDNDQIKELKKAKLETKALKAKRPGFTDERYQETSYYMENGLRKVYPYYFTFTTFTKGRWVGEKILDIFSREFRAHPAEEYERCIQTGTLTVNFEKVPIDYRLKHNDLLANIVHRHEVPVTCQPIKIVHMDEDIVVVNKPASIPVHPCGRYRHNTVVFILAKEFNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEQQIRNRQVEKEYICRVEGVFPDGIVECKEPIEVVSYKIGVCKVSAKGKDCTTTFQKLSQNGTTSVVLCKPLTGRMHQIRVHLQYLGYPILNDPLYNHEVFGPLKGRSGDIGGKSDEELIRDLINIHNAENWLGIDCDSDISMFKSTKDEADRESLSSEHTSVVHHSDDDGCVNSRETTPPCNEPQQPENSVKLLETTNAVKEYQVAAQKSSSEICPAPLDAVESPLNGGGCNVGKVTVDEHCYECKVHYRDPKSKDLIMYLHAWKYKGPGWEYETELPNWARNDWDHLDSA
The following text describes a protein:
Function:
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.
Subcellular Localization:
Secreted, cell wall. Secreted, extracellular space, apoplast.
Sequence:
MEFYHQHKTCLFSGFLIFCMIAVASSLGPIYTPPEAERLTDRFSRLSVNQGYNVFFGGANVRLTNNGSNADLILDKSSGSGLVSRDKYYYGFFNAALKLPANFTSGVVVAFYLSNQNIFPHNHDELDFELLGYDKRRDWVLQTNIYGNGSVSTGREEKFYLWFDPTQDFHDYSILWNNHHILFLVDNVPVREVVNNTTISSVYPSKPMSIYATIWDGSQWATRGGKYPVNYTYAPFVTSIKGVELEGCVSEQNASAASACARRSTSSLDPVDGEEFVKLSQQQMTGLDWARRKHMFYSYCQDTRRYKVLPPECTAT
The following text describes a protein:
Function:
Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.
Subcellular Localization:
Secreted.
Sequence:
MFKLHSFTAALAAGLLTTIVSAAGLHEAALAAGLEYFGTATDNGELTDIPYVTQLNNTADFGQITPGNTQKWDSTEPSQGTFSFTKGDVIADLADANGQYLRCHTLVWHNQLPSWVTSGSWTNTTLTAALRNHITNVVNHYKGRCIHWDVVNEEYGGAKAAGARAIVQLIKNAGVKIDGVGFQAHFSVGTVPSRSSLASVLQSFTSLGVEVAYTEADVRIQLPTSATTLAQQSTDFQNLAGSCVDTAGCVGFTIWDWTDKYSWVPSTFSGYGAALPWDENFVKKPAYDGLLVGLGGTVTTTTTTTATSTTTSATATSTATSPHWGQCGGIGWTGPTLCASPWTCTYVNDWYSQCL
The following text describes a protein:
Function:
Involved in stress response (By similarity). Does not function as cytokinin hydroxylase in yeast heterologous system (Probable).
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MLFCSVRILFIISSKQLVLISETEVTTTLTLHTTHKIESPTANPPQSKKNLFVIRMELLSTINLLAIALVLLVVPKIYGACRILVWRPWMLSRRFKKQGISGPKYRILYGNLREIRKMKNEAKLMVLDPNSNDIVPRVLPHLQQWKSQYGETFLYWQGTDPRLCISDHELAKQILSNKFVFFSKSKTKPEILKLSGNGLIFVNGLDWVRHRRILNPAFSMDKLKLMTQLMVDCTFRMFLEWKKQRNGVETEQFVLISREFKRLTADIIATAAFGSSYAEGIEVFKSQLELQKCCAAALTDLYFPGIQYLPTPSNLQIWKLDMKVNSSIKRIIDARLTSESKDYGNDLLGIMLTAASSNESEKKMSIDEIIEECKTFFFAGHETTANLLTWSTMLLSLHQDWQEKLREEVFNECGKDKIPDAETCSKLKLMNTVFMESLRLYGPVLNLLRLASEDMKLGNLEIPKGTTIILPIAKMHRDKAVWGSDADKFNPMRFANGLSRAANHPNALLAFSMGPRACIGQNFAIMEAKTVLAMILQRFRLNLSADYKHAPADHLTLQPQYDLPVILEPIDG
The following text describes a protein:
Function:
Probable E3 ubiquitin-protein ligase.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice site.
Domain:
The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.
Sequence:
MAYRNTVCTPQVIDLETEQGHSHIHSESFNRTGNDSSDQGAQHAVRGVGNATNIGLSDMRSYYDAGMNHPHQPVHNLPPNLGVDSGFVFPSSMYNPCMSTTSMNQYVSHTQSFGLPSNQVVLGSMDEGSRNENAGESARGFIKRKNAAVAGSYHCANGFASSSSSHASLNPTHRPWDPSFESNVLPNTASYNPSEYHSQTSWPSMEGSSIPSNGFNLMGAHPESAQHGNYAFPTSHISQCFQPTSNTWISQSANGIADGIPQWEYVNGMNNAPGRFSRSGMTETVNGSFREYQNGPSTLCRGPLPYFHQHAGMHAHNLLDHTQVQAPYQQCHNNPVLHGVNHSGNRFHLGPRIPVLFSNSERTFGPPHHPLLANPVNHRNIRILPPEHATIMDFSRLYEVSNVVDEHRDMRLDIDSMTYEELLALEEQIGDVNTGLAKSYIVEKLKTSLFVPGSSCMSNKSSESSMENDACIICQEEYQVKECIGTLDCGHRYHEDCIKQWLMVKNLCPICKTTALSTGRRSG
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. Its activity is stimulated by RbpA.
Sequence:
MSASTSRTLPPEIAESVSVMALIERGKAEGQIAGDDVRRAFEADQIPATQWKNVLRSLNQILEEEGVTLMVSAAEPKRTRKSVAAKSPAKRTATKAVAAKPVTSRKATAPAAPAAPATEPAAVEEEAPAKKAAAKKTTAKKATAKKTTAKKAAAKKTTAKKEDGELLEDEATEEPKAATEEPEGTENAGFVLSDEDEDDAPAQQVAAAGATADPVKDYLKQIGKVPLLNAEQEVELAKRIEAGLFAEDKLANSDKLAPKLKRELEIIAEDGRRAKNHLLEANLRLVVSLAKRYTGRGMLFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLARVQRQMLQDLGREPTPEELAKELDMTPEKVIEVQKYGREPISLHTPLGEDGDSEFGDLIEDSEAVVPADAVSFTLLQEQLHSVLDTLSEREAGVVSMRFGLTDGQPKTLDEIGKVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MWCCSGQGRQPYAIASCTSQTRVKPIRVKSGEEQEVPDDFDGPLSERSCRDVFFLLLFLAFWGGMGYVTYLALVGGNMFRLLYGVDSWGNICGVKNDVIGNVSLSGQDMTSKQFLFFYDLTDVSAIFATSTDTVRLCVKSCPSENVTSLEAIQTLAHNGTTVLCRYNVPTTSYVADGVTCPIVPVPRASPFLNRCVPDSLTSGVDGVLSSVSDAFSANTWKTILKDIELSWKDVLILTAIGFGFSLVMTALMRFFAAFIIYLTIVVFILGSLGGTGYLWYRWHSENTADPVGQNVQTFLIAAICATVVTVLVLLLLLIMRKRIGLVVQLFQEAGKAVARMPLLLLQPVWTTIATILFGAYWVVIFLYIYTAGTPVVQSNGYVTFQTDSLLEKLVWYHVFGGLWMLQFLIGCQHVTIAGAVATWFFTRNKKKMQSPISKSMGRLIRYHLGSVAFGAMIIALVQLARIILAYIQNRLKGRAGEVADFCLRCLACCLWCFEKVLKFINRNAYIMIAIYGYNFCKSAQRAFSVLVSNALRVAALNSIGDFCLFLGKVAVVAATVVVGIELLQNRADLTYYPVPIVLGAICAFLIAHCFFTVYEMAIDTIFLCFCEDEERNDGVTKPYYSSVGLRDYLQKQERAIRAKQSKKQQKQQQQQQGYDNDGYE
The following text describes a protein:
Function:
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
Sequence:
MIILMSFDGKTFEVDEAMALELETIKHMIEDDWANNTIPVANVTGKILAKVIEYCKCHVEVSKVEDKIAKEDLKSFDAKFVKVEQGTLFESHAVADMIKEKTPEEIYKTFNIENDFTPEEEEKIKRENAWAG
The following text describes a protein:
Function:
May amidate Asp of the extracellular death factor precursor Asn-Asn-Trp-Asp-Asn to generate Asn-Asn-Trp-Asn-Asn.
Subcellular Localization:
Cytoplasm.
Sequence:
MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLELEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL
The following text describes a protein:
Function:
Plays an essential role in sperm motility and male fertility by stabilizing the sperm flagellar axonemal structure. May be required for the stability of ODF2 and MANS1 proteins. Dispensable for the assembly and function of motile cilia.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Localizes to a polar structure adjacent to the basal body.
Sequence:
MPAKDKRKDKRKDKRKGKNKGKEPKKIIKSDEPAIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYNMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLAKTKEKAQEEKEKLEQKYALQVSELEGQFHQKAKEIGMIQTELKTIKQFQKRKIQVEKELDDLKENLRNSEKNYQETLRRLESRFFEEKHRLEQEAEKRIIMLAERAHHEAVVQLNTAGRNVFKENVYLHKALAYHLKEAEILQQNSKKIEENHSCLLQQKEINDLLVKEKIMQLTQQKSQIQTLQKKVVSLENALTYMTTEFEAEVLKLQQKAIIENQAGLVEIDKLQQLLQMKDREMNRVKRLAKNILDERTEVEQFFLDALYEVKQQILASRKHYKQIAQAAFNLKMRAACAGKTEYPRIRTFDGKEQSTNSVNQDLLEAEKWPTTQKNVDIRDLTWEQKEKVLRLLFAKMNGFAARKYSQSSKPPVPDHIIYGSGEMKETGDENNLLDQTFITQQAPVSDSNRMVSPDVIPQGLQDSDIA
The following text describes a protein:
Function:
Together with RPP13L4/ZAR1, involved in the regulation of the ambient temperature-sensitive intersection of growth and immune response in the absence of pathogens.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MGWWRKKKKPKSEIASERGAKLLKDLIECCDGKSNPIKFFSADEIRKATNNFGVSNLVSELSHDFDYKWYSGKNENHDMILVRKAFSQSVYYKDTFFRDIAVSSMVSGHKNFLKLIGYCLEFEEPVMVYHGVKKHYHLESSEQPWKRRMKIAEDIATALAYLHTAFPRPFVYRCLSLTNILLDEDGVAKLMDFSFCVSIPEGETFVQVDYIAGTVDYLKPNYLKHGVVSEETDVFAVGHSMQMLLMGEKIFDRIMRRPFPTSKFMEEPKMDEIADPEMGEISEEELCQMKAFLLLSLRCTGHVGEVPTMVEVAKELKSIQRCLHNDTFSPSVETQFDSHQDISSSVILSNQTKDTRALLRCIACHVFDEMFQWVMMNWFRFFRRNRRIC
The following text describes a protein:
Function:
Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MMPRLLLRDWPRCPSLVLGAPSRPLSAVSGPAEYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLSAQKPLLNDSQFRKTEVLCKDFENGIGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKTLRAGLLEPEVFHLNPARSDTDAFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRIPKPSRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNPSEIQAHLKYILSDSSPVPEFPLAYLTSENRDVWAELRQKLIHGGNEETLRKVDSAVFCLCLDDFPMKDLVHLSHTMLHGDGTNRWFDKSFNLIVAKDGTAAVHFEHAWGDGVAVLRFFNEVFRDSTQTPAIAPQSQPAATDSSVSVQKLSFKLSSALKAGVTAAKEKFDATMKTLTIDAIQFQRGGKEFLKKKKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASIFTKRCSEAFVREPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLFALRYLAAARGVTLPELYQDPAYQRINHNILSTSTLSSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVSSYSGRNAREFLHCVQKCLEDMFDALEGKAIKT
The following text describes a protein:
Function:
One of the sliding clamp subunits that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. Heterotrimer stimulates the Holliday junction resolvase Hjc. DNA polymerase I, DNA ligase and the flap endonuclease may be constitutively associated with the PCNA heterotrimer forming a scanning complex able to couple DNA synthesis and Okazaki fragment maturation.
Sequence:
MFKIVYPNAKDFFSFINSITNVTDSIILNFTEDGIFSRHLTEDKVLMAIMRIPKDVLSEYSIDSPTSVKLDVSSVKKILSKASSKKATIELTETDSGLKIIIRDEKSGAKSTIYIKAEKGQVEQLTEPKVNLAVNFTTDESVLNVIAADVTLVGEEMRISTEEDKIKIEAGEEGKRYVAFLMKDKPLKELSIDTSASSSYSAEMFKDAVKGLRGFSAPTMVSFGENLPMKIDVEAVSGGHMIFWIAPRL
The following text describes a protein:
Function:
Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.
Sequence:
MAQNQESTPEVETMASIEGSEAEKLEGAGASPEEGSVKLGGESCGLPEDDTQNTADPNCLPKESADATEEAKALNPPDASEEGKDTEPLPEASIQRESSGIDAIIENREELSDASAESGGNVTTEVRQDHNKMQVDDDNNGLNNDSETGEKVSPESCMQVDPIAAIPSTSDGKGVKGEEPLGAEGGEVSPGKLSAAQCLYQVKWIKWKGKDTPIVTQNENGPCPLLALMNVLFMTWKVQLPPGTEVVTSDQLMDYLGDCILSSAPKNCTEGQLLNYEQNFHDAMSVFHKLQTGLDVNVKFTGVRHFEYTPECIVFDLLGIVLYHGWLIDPQNLDIVTAVGNCSYNQLVEKIISSKSAQDSEVVSQGMMAEAYLESTASQLTYHGLAELSGTVKEGEFCVFFRNNHFSTMFKHKSELFLLVTDQGFLGEPNVVWETLSNVEGDSTFVDADFRTTVPNHGGSPQVPLSSQQQIDQVLKTVVSSLGDSFRTLARYAPLPPQSKQQMDQDYLVALTLQQEAAQDGEQQPAAMSDLELAKKLQEEEDARAQQLYAQQLQQQQQQQQRQQQQQQQAAGAAQPQPLPPQAQPIPAGQPPRKKEAPSQPKPPTPPQPSQPVSTGGQPPAAPKKKEDKCTIL
The following text describes a protein:
Function:
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MAQDPYALLQKADKAAAGASGGFSLFGGRQEKWENAAELYNQAANAFRMQKQNKEAGQAFERAADIQTNKLNEPDDAANTLTEAFKVYKKGDPLDAVRCLDVAINHYTSKGNFRRAATHKQNLAEVYEMEIGDMKKAIESYELAASWFEADNAEALANKLFLKVADIAALDGDYYKAIEHFEKVAASSVSNNLMKWSVKDYFLKAGLCHLAIGDTVATGRAFEKYRDMDPTFPSTREHQLLIDLAEAVDQGDQEQFADKLFQYDQMSKLDKWKTTILLKIKSAIEEKGDDFS
The following text describes a protein:
Function:
Probable transcription factor. May bind to the promoters of target genes, including micro-RNA genes, in order to repress expression, and acting redundantly with flh-1 and flh-3.
Sequence:
MVDTMMNTNTDGVTAVPPIFPLPSTTPNRNNNNELAMLAQKQIVAGLLLQQPTIVQAAVNGTNSQKHLADIDYTNVIQTLQALGTTNLKAFSLLLDPQSQTSQLISEDTRPSASSSPSSTATAVSNSGQSNATSTSSSSTEPEYKPRNVREKVYADGYIMSFDKKSCCGTKEFWRCERKNDCNARMHSDINTREIVRKLHPHNHEKPSPEELAFYEQDFSTLHPNYCHPVKSINRSYMQRKLSRASHVSQALPIAPQQIKAEPMEVDTTNQTIQNFQQNNNLMLLASINAAATAAAAATSAGISPPVVGQKRVSTTVMPITLKSQRTTPKEEEDSSQLMSQEEFRITYELTKKLMEMMKPKTEIGVRWQGDEGSILLFLSHDNGAEENVFFPVVVMNRDEKSLITALEGFTGKRCEGKLALCYSQRVNVLVHEALISNWTHGKLFLVNTDAPALWRLTPVDAFGEPLNHV
The following text describes a protein:
Function:
Required for the transfer of reducing equivalents from stroma to thylakoid lumen. Involved in the biogenesis of the plastid cytochrome b6f complex by probably transferring reducing equivalents from stromal m-type thioredoxin (Trx-m) to the lumenal thioredoxin HCF164.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Sequence:
MNLSVNRCITGGFVGGFSSCRLNHEKRWVRAGKHCELERERSLVSDAVSLERLESKSIKLAMLASGLGVANLVTLSSAKAADLKMIVLDQATSIYILAEGSLGDSVGNFLYSANQQANEAVQDQLSALSVTSLAVIFGAGLVTSLSPCTLSVLPLTLGYIGAFGSGKSRGQVIGDTVAFALGLATTLALLGIVASFAGKAYGQIGQGLPVAASGLAIVMGLNLLEIIELQLPSFFNNFDPRAAAANFPSSVQAYLAGLTFALAASPCSTPVLATLLGYVATSRDPVIGGSLLLTYTTGYVAPLIVAASFAGALQSLLSLRKVSAWINPISGALLLGGGLYTFLDRLFPAATMVM
The following text describes a protein:
Function:
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
Subcellular Localization:
Cytoplasm.
Sequence:
MIDLEALPHLPGCYLFKDEEGVVLYVGKAKDLKKRVSSYFQKRDHDPKTTSLVQAARGLDFIVTNTEVEALLLENTLIKKHWPRYNILLKDSKRYACIHLTGEKFPRIRIARKNTGDGEFFGPFVSAKERDYIFEVVRKTFQLRTCKKMPSRACLRYHIGACSGPCIGSISEEEYGEKVKRATSVLKGNIGELIESMEKEMKKMAAKQMFEQAMALRDEISALEYLQEKQNMERQKKHDEDILNYIVRDNTVYLMLFKVYKGTLEDKQDYVFAFGEDFLQEFLVQYYSENDPPEELIVPQVLEESLVEFLAHVKGKKVKVTVPKQGEKKELLDLALKNVEIGFFGDRKKLESLQSKLSLPKLPNVIECFDISHLSGTSTVGSMVQFRGGRPDKHNYRRFKIESVEGIDDFASIAEVVRRRYSRLLEDKHEMPDLIIIDGGKGQLSSAFQELRKLKIRVPIISIAKREEELYVPGLKSPLPIKRNEKASLFVQEIRDEAHRFAITYNRLLRQKSLIK