lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable transcription factor required for the initiation of inflorescence trichomes in response to gibberellin (GA). Mediates the induction of GL1 expression by GA in inflorescence organs and is antagonized in its action by the DELLA repressor GAI. Acts upstream of the trichome initiation regulators GL1 and GL3, and downstream of the GA signaling repressor SPINDLY (SPY). Does not play a significant role in the cytokinin response. Controls trichome branching through GA signaling. Acts downstream of the key regulator STICHEL (STI) in an endoreduplication-independent pathway. Controls trichome cell division indirectly by acting downstream of a key endoreduplication regulator SIAMESE (SIM).
Miscellaneous:
MISCELLANEOUS: Plants over-expressing GIS have delayed shoot maturation and flowering, and a strong production of trichome on the inflorescence.
Subcellular Localization:
Nucleus.
Sequence:
MDEATGETETQDFMNVESFSQLPFIRRPKDKNPKPIRVFGKDFTGRDFSITTGQEDYTDPYQTKNKEEEEEEDQTGDNSTDNNSISHNRRFECHYCFRNFPTSQALGGHQNAHKRERQLAKRGVSSYFYHPDNNPYSYRHYPSWTNGPLTAARSYGGFSSGPKPSGYYTRPSYGSQLGLWRLPPRVQGVYNSNAAFTSNGSSSSSNSTLPLLTRSQTQLSSQVGGSAAQNRMSSYGYGLSPNVQDHVSLDLHL
The following text describes a protein:
Function:
Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone) also known as VAI or N-(beta-ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3-furanyl)-hexanamide, an autoinducer molecule which binds to LuxR and thus acts in bioluminescence regulation.
Sequence:
MTIMIKKSDFLAIPSEEYKGILSLRYQVFKQRLEWDLVVENNLESDEYDNSNAEYIYACDDTENVSGCWRLLPTTGDYMLKSVFPELLGQQSAPKDPNIVELSRFAVGKNSSKINNSASEITMKLFEAIYKHAVSQGITEYVTVTSTAIERFLKRIKVPCHRIGDKEIHVLGDTKSVVLSMPINEQFKKAVLN
The following text describes a protein:
Function:
Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box via its ATPase activity (By similarity).
Subcellular Localization:
Nucleus. Note=Localized on chromatin.
Sequence:
MTTRLDRLVVLLDSGSTSVVRETAAKQIGDIQKVHPDELYNLLGRVVPYLKSKNWDTRVAAAKAIGGIVENVPVWNPNRTSPVKKEETEDLPSFNGDTEEKPFIKTEEGAPASSQSQVVVSSNLTSNSEVSKLEEERLSTRSHSQEIKPIVDFGPDEETAKELNTELKGKFENSLLSFESFDIANVLKAGKKLLGSASRDYDVNPANYSTHYLQQLSNLKSRLDLAGEYLDDSIMNDLGDNVGSNSKGSPTTSIPEHKTSINNNKPEDTPTPSENVHLSARQRNALKRKARQMKNSQKVRVIDVAPTLVHQQNSTSSADKKTGADYNFTAQSRSDRLVVEHKAPIVPSAAVAVTSDSVWPFETLVELLLIDMFDPSWEIRHGACMGLREIIRYAGFGYGRVVGKSEAENEQLNKKYFDDLLCRIACVFALDRFGDYLADQVVAPIRESVSQVLGVALIYVPNDSVFSMYKVLHSLVFQNELGLTNTVWEAAHGGMLGIKYLVAVKYPLFFSHSDYLDSLINTVIHGLANHDDDVRAVSALTLLPIADKLVQEKLSSCKNLLKVLWDCLDDVKDDLSSSTSCVMDLLSSLCSFTEVMNLMQETANSDPEFSFETLVPRLFHLMRYTLTGVRRSVVYALTKFISVQTSCSWITGLTLRLCFQNVLLEQQEDISKSSCELAQRVMDILYRDGPESFSKLLYSHIEPMLKVSITPIGSFRRPYPLDTTLIVKPSGQPYAPSTSRERNNNISELSNSRTKHRAKDDPKGSFCFSVDEPMLNGDVEFVGEERMLKARLRASSLLGRIIGRWKRDEILLFFKPFLQACLTSSFSTPVVLGSRLIESFFEVEDNDLTIQKDELYHLLCDQFATVPRENYANLVSQLHVVRAQCNALLNTFLDVGRLSRSKIPSLAVVVKGDPEAGPIAFGIADAEKLVGPTYENLCKLLSPSQKAQSSKALNEIKYLIIDEISIYKIAKERQDIQCSASIASAMVTYDKLPKKLNSIIKGIMESIKKEQFSCLQMHSASAMMKLISACYKESRQVISEKIVRNLCAYVCMDTTETPIFHDSGKNGILSLHSIGTSDDNDEQVSGKLVDDSDDVSNDRKSSLSSVSDKDAAVLQRMGAQLTLQQMAQNFGSSLFSRVPVLSQCLFVPLQQYAESGFPSEVDQASCTVGQDLLDAMSILRFLVAYLDSGLQSEIVSTLPHLLATLQSNYSAVRNMASKCFAAITESNAAGSKALHLLVEDVVPLLGDASSTIHRQGAIECIYHVVQRLGVRILPYILYLIIPLLGRMSDADQDVRVLATTSFATLVKLVPLEAGLPDPPDLPQYLLDSREKERKFLEQMLNPSKVEAFSIPVPISADLRKYQQEGVNWLAFLNKYELHGILCDDMGLGKTLQTICIVASDHYNRQKLFEESGSPKFAHVPSLIVCPSTLAGHWQQELSTYAPFLKVSAYVGPPAERAKIRSKMKKSDVVVTSYDICRNDVDELVKIDWNYCVLDEGHVIKNARAKLTKAVKSLRSYHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKTFQERFVRPIAASRDAKSSSKERERGTLALEAIHKQVLPFMLRRLKEDVLADLPPKIIQDYYCDMSDLQRKLLNDFVSQLNINEELEDDETEKTQGTRKKKSQKAHIFQALQYMRKLCNHPALILTEKHPKRNAIVKQLAKENSGLHDLKHAPKLTALGQLLRDCGLGNSSVNSNGIDSALTNAVSEHRVLIFCQLKDMLDMVEKDLLQATMPDVTYMRLDGSVEPTKRQEAVTKFNNDPSIDVLLLTTHVGGLGLNLTGADTVIFVEHDWNPMRDLQAMDRAHRIGQKKVVNVYRLITRGCLEEKIMGLQRFKMNVASTVVNQQNAGLSSIGTDQILDLFNTTADEQQTVQNIDKEESEDAAGRGLSGTSKKALEGLPEMWDESQYDEFNLDGFISTLPKDAS
The following text describes a protein:
Function:
May act by regulating membrane trafficking and cellular morphogenesis.
Subcellular Localization:
Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle. Recycling endosome.
Sequence:
MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSERSSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVEIRMAEGEAEGSVKEIKHSPGPTRTVSTGTALSKYRSRSAEGAKNYLEHEELTVRQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSEFNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNHALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDAFEDGGRQSLMEMQSRHGARTSDSDQQAYLVQRGAEDRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII
The following text describes a protein:
Function:
Acts as a guanine nucleotide exchange factor (GEF) for Rho GTPase. Has a critical roles in the generation of rhythmic behaviors: feeding, defecation and ovulation by dynamically regulating the concentration of intracellular calcium. Plays a role in male tail tip morphogenesis.
Domain:
An acidic domain (AC) contains three highly conserved tyrosines that are involved in the autoinhibition of GEF activity.
Sequence:
MSRRSTTTSTNFGLSWSLVDVISSSTAVFKVPMNGGCDLWIGCARWLRDMKVLTTDKNGTMLEFASVLRDGILLCRLANTLVPNGIDQKKIMRTNQPSPFLCCNNINYFAMFCKTYFNLEDADLFTAEDLYYMNGFQKVLKTLSFLSHTKESLSRGVDPFPDTDNNQEGTSNGSEFEDDVEIYQSLHDNIENVDPNRTIYGPITSADPEEQQSEQLYDRIVTNRKPSMNENDLQNTPTLKRNRCIRELYDTEKNYVAQALVTIIKTFYEPLKGIIPTSDYNIIFGNIEEINVLHTALLADLEYPVKVALGLSDATPPRPISLNECVPQTIGEVFIKYRDQFLAYGKYCSNLPDSRKLSNELLKTNEFISRNINELTAQGNCKFGMNDLLCVPFQRLTKYPLLLKELQKKTDLASPDRKSLEEAVEVMEDVCNYINEESRDTNAIKVIDEIEQSITDLSMPLNVKLHDYGRVNLDGEVKMAESTLTQAGKPKQRYIFLFDKVIVVCKAANKVMAAKTTGASARTNTFTYKNAYVMSELTIDKNASLDVKSGGTITRRTQYVIIMTRDRNENNEITQLTFYFKNEATRNNWMTALLLSKSNVSPTDYLRDTNHKVAFHSFRVDVKNPATCDVCDKLMKGLQYQGYKCESCNMSMHKECLGLKKCEAVRKSTHETRSSQSFNCNRPRFHIHEGDIVVANSNSTPSDLSYLQFAKGDRIEVIKMQGHNRFTGCLINNRNRTGLVHLDHVSQSRTTSMIGLSPIDSPAGSIAPRVVRNESTVLPNKLLSDGSSRSLSGPHGSRSSRNSSSSTINGSMDSVPRQQDYVNTEISEFLWYMGEMERAKAESTLKGTPNGTFLVRYSKNRKQTAISLSYKNDVKHMIIEQNSDGKVYLDEDYIFNSTVELVQYYRSNNLIEIFAALDTCLKNPYSQCKVFKAVHDYDAPSPNNEGKFLSFKTGDIVVLLDTVGEDRGWWKGQVNNKSGFFPLSYVKPYDPATEGSSSPVTPTSSSS
The following text describes a protein:
Function:
Involved in regulation of lifespan. Required for dopaminergic CEP neuron degeneration in response to Mn(2+). Inhibits the skn-1-mediated up-regulation of tatn-1.
Sequence:
MGNWITSTFLRFDLFQRHQPNRFLEYTRVQHSNQSPAYSVRTAAEIVAHQRMKPNHSNDSDTDFSSDDEGCPKMTPHEEQQMFEREQHIAFSGRCHIGDPESCTQLRNEINSRCGPRPSTSNNMEFILNRDLQKRGTSISNPRTVARVLNSHLPNQKRRVDRVATKSFCTQYIQNGTKIVVASQDEKIRFYQRNPDKSKYRSKYMKSDELRVDQCGWSILDTAISLNGDLIAYGTWKDAVFVGKLDFTERQNITWFPIDLNGEPGRDHCAVFCVKFSDSSEQIVCGTSQYSIHVFDVEQRRRIRTIVNAHEDDVNSVCFADLGSNLIYSAGDDGLVKVWDKRAWSDGDVEPVGVFAGHRDGVTHVDSRQDERYLLSNSKDQTIKVWDLRKFSNMSGVEATRACVQSQHWDYRWQPAPPGLCQPVAGDTSVMTLRGHSVLHTLVRANFSPESTGRRYIYTGCARGEVVVYDIMSGTVSRRLKGHTAVVRECDWHPTENEIVSSAWDGVTTVWTWDERQEGVIAPYDHPNISQFGDEDSCDELFQPVKKQCRRQRKTMSSRGHPCSSSSISQN
The following text describes a protein:
Function:
Probably involved in membrane trafficking.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein.
Sequence:
MIRQNDPNLIDEEEVNPLLKVATTPGSRSSVPLTASANLGFNEKYDAVVDIPLDTSNGSNKKKRTCSLGVSIDAQRLQYLAFTSWLGIVLCLVFNIIAVTDYWIKGRGTKIFLLVIIYVLVGCPLSYVLWYRSLYRAMRMNSAMNFGWFFLVYTIHICFCIVFTIAPPIVFEGKSLMGNLAAIDLFSNHVLVGDLITYQIRHRLHP
The following text describes a protein:
Function:
Mediates influx of magnesium ions. Mediates Co(2+) uptake. Has high selectivity for Co(2+). Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Domain:
The central ion permeation pathway is formed by the first transmembrane domain from each of the five subunits. Mg(2+) binding strengthens interactions between subunits and leads to the formation of a symmetrical homopentamer surrounding a closed ion permeation pathway. Co(2+) binding also induces a conformation change. Low Mg(2+) concentrations trigger both a conformation change within each subunit and a loosening of the interactions between subunits. This results in an open ion conduction pathway. In addition, this results in a less symmetrical shape of the whole complex.
Sequence:
MEEKRLSAKKGLPPGTLVYTGKYREDFEIEVMNYSIEEFREFKTTDVESVLPFRDSSTPTWINITGIHRTDVVQRVGEFFGIHPLVLEDILNVHQRPKVEFFENYVFIVLKMFTYDKNLHELESEQVSLILTKNCVLMFQEKIGDVFDPVRERIRYNRGIIRKKRADYLLYSLIDALVDDYFVLLEKIDDEIDVLEEEVLERPEKETVQRTHQLKRNLVELRKTIWPLREVLSSLYRDVPPLIEKETVPYFRDVYDHTIQIADTVETFRDIVSGLLDVYLSSVSNKTNEVMKVLTIIATIFMPLTFIAGIYGMNFEYMPELRWKWGYPVVLAVMGVIAVIMVVYFKKKKWL
The following text describes a protein:
Function:
Required for the use of extracellular DNA as a nutrient.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTGSAEARIDAVLLQAEQQLARSLQITKPRLLEQQQLREQRSQRQRQRQFTRDWQSALEALAALLPEHAWLTTISWQQGTLEIKGLTTSITALNALETSLRQDASFHLNQRGATQQDAQGRWQFEYQLTRKVSDEHVL
The following text describes a protein:
Function:
Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTLLTVNPFDNVGLSALVAAVPIILFLLCLTVFKMKGIYAALTTLVVTLIVALFVFELPARVSAGAITEGVVAGIFPIGYIVLMAVWLYKVSIKTGQFSIIQDSIASISVDQRIQLLLIGFCFNAFLEGAAGFGVPIAICAVLLIQLGFEPLKAAMLCLIANGAAGAFGAIGLPVSIIDTFNLSGGVTTLDVARYSALTLPILNFIIPFVLVFIVDGMKGIKEILPVILTVSGTYTGLQLLLTIFHGPELADIIPSLATMVVLAFVCRKFKPKNIFRLEASEHKIQKRTPKEIVFAWSPFVILTAFVLVWSAPFFKKLFQPGGALESLVIKLPIPNTVSDLSPKGIALRLDLIGATGTAILLTVIITILITKLKWKSAGALLVEAIKELWLPILTISAILAIAKVMTYGGLTVAIGQGIAKAGAIFPLFSPVLGWIGVFMTGSVVNNNTLFAPIQATVAQQISTSGSLLVAANTAGGVAAKLISPQSIAIATAAVKKVGEESALLKMTLKYSIIFVAFICVWTFILTLIF
The following text describes a protein:
Function:
Plays a key role in the control of the eukaryotic cell cycle. Required for entry into S-phase and mitosis. Acts as a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II. May function in concert with npp-16 to arrest prophase blastomeres in response to anoxia.
Subcellular Localization:
Nucleus.
Sequence:
MSGQPSIDDYAKIEKIGEGTYGVVYKGRHKASGRFVAMKKIRLDSEEEGIPSTAIREISLLKELVHPSIVTLEEVLMQEGKLYLVFEFLSMDLKKYFDSLPIEKLMCPNLIKSYMQQILEALLFCHRRRIIHRDLKPQNLLIDAKGMIKLADFGLARAVCIPMRAYTHEVVTLWYRAPEVLLGCPRYCPAVDIWSVGCIFAEMASKKPIFRGDSEIDQLFRIFRTLTTPTEENWPGVSEMPDYKATFPSWKVNNLRQAAKYMDDDALDLLEGMFIYNPTKRISAVTALKHKYFDTDVHMKENQSARANF
The following text describes a protein:
Function:
Component of the endoplasmic reticulum (ER) quality control system called ER-associated degradation (ERAD) and involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Functions as an ERAD substrate-recruiting factor that recognizes misfolded proteins for the HRD1 E3 ubiquitin ligase complex. Targets the misfolded LRR receptor kinase BRI1.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MRILSYGIVILSLLVFSFIEFGVHARPVVLVLSNDDLNSGGDDNGVGESSDFDEFGESEPKSEEELDPGSWRSIFEPDDSTVQAASPQYYSGLKKILSAASEGNFRLMEEAVDEIEAASSAGDPHAQSIMGFVYGIGMMREKSKSKSFLHHNFAAAGGNMQSKMALAFTYLRQDMHDKAVQLYAELAETAVNSFLISKDSPVVEPTRIHSGTEENKGALRKSRGEEDEDFQILEYQAQKGNANAMYKIGLFYYFGLRGLRRDHTKALHWFLKAVDKGEPRSMELLGEIYARGAGVERNYTKALEWLTLAAKEGLYSAFNGIGYLYVKGYGVDKKNYTKAREYFEKAVDNEDPSGHYNLGVLYLKGIGVNRDVRQATKYFFVAANAGQPKAFYQLAKMFHTGVGLKKNLEMATSFYKLVAERGPWSSLSRWALEAYLKGDVGKALILYSRMAEMGYEVAQSNAAWILDKYGERSMCMGVSGFCTDKERHERAHSLWWRASEQGNEHAALLIGDAYYYGRGTERDFVRAAEAYMHAKSQSNAQAMFNLGYMHEHGQGLPFDLHLAKRYYDESLQSDAAARLPVTLALASLWLRRNYADTVLVRVVDSLPEVYPKVETWIENVVFEEGNATILTLFVCLITILYLRERQRRQVVVVADPVAADVAQPLDADVAQHLAAFPR
The following text describes a protein:
Function:
NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis and drug metabolism.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MDILTAPVLIGVSIVVITVLYLFLKPAGSNSTPPKPQNKIPKALQDPSVKYPLPLIEKEEINHDTKRFRFGLPSSSHVLGLPIGQHIYLSAKVNGSLVVRAYTPVSSDQDQGYVDLVVKVYYKNTHPSYPDGGKMSQYLDNMKIGDTIDFRGPNGLLVYNGKGKFAIRPDKKSEAEVRKFKHVAMIAGGTGITPMLQLIRSITADSFDETVCSLIFANQTEKDILLRNELDEVHRNHPSKLKLWYTLDRPSEGWKYSEGFVNAAMMKDHLPPADSDVLVVMCGPPAMIEKACLPNLLKLGYKKENIFAY
The following text describes a protein:
Function:
Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing (By similarity).
Subcellular Localization:
Cytoplasm. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell projection, bleb. Note=Predominantly cytoplasmic.
Domain:
Regulated by intramolecular binding to a C-terminal auto-inhibitory domain. Effector binding abolishes this interaction and activates the protein (By similarity); The DAD domain regulates activation via by an autoinhibitory interaction with the GBD/FH3 domain. This autoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2 domain to then nucleate and elongate nonbranched actin filaments (By similarity).
Sequence:
MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSAQIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYGSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIQAVNAVASATGTLPWANLVSILEEKNGADAELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQRFLGTAGTDVDLRTQLTLYESALRLEDGDMEEAAAAAAAGGRRERRKPSSEEGKRSRRSLEGGGCPVRAPEPGSTGSASPVGSTPSTGSAPPTNPAFSSTGPASGLLRTSVNLFPTISVGPSVDSSCERSVYKARFLENVAAAETEKQAALAQGRAETLAGATVDDTDGSSGTRELWDSPEPASAPRTPQSPVSRILLRTQRSLEPEPKKPVSPPSPKAEPIQEPPTCVPKLCIGDLDFSDLGEDEDQDTLNVESVEAGKASPFLSSLSPSLSGGPPPPPPPPPPITGSCPPPPPPPLPPPATGSCPPPPPPPPPPIIGSCPPPPPLAAPFTHSALDGPRHPTKRKTVKLFWRELKLTGGPGCSRSRFGPCPTLWASLEPVSVDTARLEHLFESRAKDVLPTKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGPAENFLMTLASIGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLYHLCSLVLQTRPDSSDLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELSPALRARLTHFLAQCTRRVAMLRVVHRRVCNRFHAFLLYLGYTPQAARDVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERNKTRGRMITETEKFSGVAGEAPNNLSVPVAVGSGPGQGDTDNHASMKSLLTSRPEDATHSRRSRGMVQSSSPVSHTAVGPSAASPEETAASGLPTDTSDEIMDLLVQSVTKSGPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAPGLEV
The following text describes a protein:
Function:
Regulatory protein of the TOL plasmid xyl operons. XylS activates the xylXYZLTEGFJQKIH operon required for the degradation of toluene, m-xylene and p-xylene.
Subcellular Localization:
Cytoplasm.
Sequence:
MAGLQHARIGASLEVASASLAGHRFEKHSHDEFVISANLCGLEDVWLDGRTFQADSGDLTLYNPGQIQGGGVRDGQPWRFASLYLPAAELASSLDLSSVEFDRPLLRSPALGRELAASIEALLASDRFARERGEERLLEFLGRLLAASGTRLPQRADPGRPAVARLQALLAERLAEPPDLDGMAEQVGLSKYHLLRAFKKATGLSPRQWSMQLRTRRALGLLRRGLAVGEVAHALGFADQSHLTRYFTSAYGISPGRYQRAVRG
The following text describes a protein:
Function:
Involved in embryonic dorsal-ventral patterning which is generated by a series of serine protease processing events where gd processes snk which cleaves ea which then processes spz into the activating ligand for the Toll receptor. Required during this process for the secretion of ea from the developing embryo into the perivitelline space and for ea processing.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MLTKALILFGLLALAQGYSFTSREVKCHVCKAVVTELEEAIAKEDPHKMADVSGFRLDAQGNSISKKVRLVKSEMFLTELMEKICEKMDDYLKATYKSNGKFTLLKMIINGQMNPDSSLVDFVQDGDLNKSLGHFCNEVLEDNDEIFVKAFQAEELGNDLDIKICSEQASYCDESPVQEEYDFDGKEEL
The following text describes a protein:
Function:
Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes. Associates with sites of DNA damage and modulates the MEC1 signaling pathway and the activation of RAD53 in response to DNA damage at phase G1. The complex also physically regulates DNA polymerase zeta-dependent mutagenesis by controlling the access of polymerase zeta to damaged DNA.
Miscellaneous:
MISCELLANEOUS: Present with 238 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSFKATITESGKQNIWFRAIYVLSTIQDDIKITVTTNELIAWSMNETDTTLCQVRFQKSFFEEYEFKPHEIVFGENGVQVIEDTYGNSHKLYSFRVNGRHLTTISRKPDGDGIKSFTIAVNNTSTCPESLANRLIVVIEMDSLIVKEYCPQFQPIKYDPIIINLKYKRRFLDVFGTAASDRNPQEPLDPKLLDVFTNTERELTSALFNEEVESDIRKRNQLTAADEINYICCNSTLLKNFLDNCNVNVTDEVKLEINVHRLSITAFTKAVYGKNNDLLRNALSMSNTISTLDLEHYCLFTTIEDEKQDKRSHSKRREHMKSIIFKLKDFKNFITIGPSWKTTQDGNDNISLWFCHPGDPILMQMQKPGVKLELVEVTDSNINDDILEGKFIKTAISGSKEEAGLKDNKESCESPLKSKTALKRENLPHSVAGTRNSPLKVSYLTPDNGSTVAKTYRNNTARKLFVEEQSQSTNYEQDKRFRQASSVHMNMNREQSFDIGTTHEVACPRNESNSLKRSIADICNETEDPTQQSTFAKRADTTVTWGKALPAADDEVSCSNIDRKGMLKKEKLKHMQGLLNSQNDTSNHKKQDNKEMEDGLGLTQVEKPRGIFD
The following text describes a protein:
Function:
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (By similarity). The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity). Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (By similarity).
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MRRSPPKPWENNSGGGGSTSMTGSGGISRPMSGPQRTTSPGGGSSTTTQTSTLNNTGSPSTSVGGPLVTRPRTPMRPWESGGAGSSSIDSFGGGVGGSSGYRSSYGGGYRDSYSSGGYGSSGYGSSYGSGGSGGYGSSLYGGGGYSSGGYGGSGYGSSYGGGYGSSYGSGYGSSYGGSGYGSSYGGGYGSSYGGGYGGGYGGGYGQRGYDNMDGKGGALQSVVSSGHSWMEALHSIVDTFSRFSRLLDANFDAVHGSFSSIIRLCQSMSHFSYEIMAIIKTYSLFRMFQSVASRFLRVFRYLLGKKSKSNSSNNNTSSKFGSNAITESLRQANMDVSDFRNFQNEKKQSVGTLILIIAATFIGVPMVIGQLLNLRRRGQASRLDKGWEEQQGGGYGQVKAIYEFNPETTRDLPLRVGDIVNVIDKPHDNWWVGECNGLSGFFPVDFTEKISPNDINNNNNNNNNNNNNINTSVQIYDNNNGFNRNNSNNNLNNSEYSDYSSSNNNNNNNNNNNNNSNYQLQSNFSSNNDGISKNIIYNNNNDNQRPISPSKTSQQLSRSELMDKPYVEES
The following text describes a protein:
Function:
Serine/threonine protein kinase involved in a signal transduction pathway that plays a role in yeast cell morphogenesis and cell growth. This pathway seems to start by SMP3; then involve the kinase PKC1 that may act the BCK1 kinase that then phosphorylates MKK1 and MKK2 which themselves phosphorylate the SLT2/MPK1 kinase which itself then phosphorylates and activates the transcription factor RLM1. Directly phosphorylates BCY1 upon TOR complex 1 (TORC1) inhibition.
Miscellaneous:
MISCELLANEOUS: Present with 3230 molecules/cell in log phase SD medium.
Domain:
The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
Sequence:
MADKIERHTFKVFNQDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADEPVCSEKFEFSFESVNDMEDLKQMVIQEVQDFRLFVRQPLLEEQRQLQLQQQQQQQQQQQQQQQQPSDVDNGNAAASEENYPKQMATSNSVAPQQESFGIHSQNLPRHDADFPPRPQESMMEMRPATGNTADIPPQNDNGTLLDLEKELEFGLDRKYF
The following text describes a protein:
Function:
Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MNPWILAIRPRTLPAAIGPLLIGNILALHLERFSWLIAATSMLCAILLQIAVNLANDYFDFKNGIDTAERIGPVRVTQSGMIPPNTVRNAMVLCLLLALAVGSYLIWHGGWPIAILAAAAILGALGYSGGPYPLASHGLGEVAAFVFFGLVAVVGSYYLQAGDTTINAWLLGCAIGLFNAAIMLVNNTRDIRTDTQAGKHTLAVRIGEAQAKVLYQALIYLPFGLVIAGFLLGILPGLPVLLAGLSLLIARKLSSDFYAVSGEALNPLLGRTAKLTMIFSTLFSVGLVFTA
The following text describes a protein:
Function:
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.
Subcellular Localization:
Secreted.
Sequence:
MTTTRALALVVLSCWACLGLDVSKTDPAGQAAAALVQQMTLAEKIGMVHGNQSAADPVQAGYVGFSLGVPRLGVPGITMNDGPQGFRGPPGTSTQFPSGMTVRDRFYQYPHETAQAHGAPSCSLTDSTLPQVGMAFDTELMYEFGAAMGREFAGKGCFVQFGPGLNIHRLPWGGRNFEYCSGEDPFLGQTLARAVVQGIQDQGIIANPKHFINNNQETDRHAVSENVDERTEMEIYLPPFEGAAQAGALSAMCGNNRVNQAFACANNHTINMLFRELAGFKGWMLSDYQGTQSTVASALGGLDQQMPGCSHPNATNPLNCASDSIRPNYFGEPLEEAVRNGSVPEAVLDAKVTRIIRSLIVSGAFNRTRDPDQTASTNVTNGQQREVAHRLALRAATLLRNQDHQLPITSNHRVAVLGTAGHDRPITGGFGSGAVTPSRIVTVLDGLRHAGVNVSYANGTDVHHARALAQTADIAVLVLATLSGENQDRATLDLDQAELVEQIAQVQPHLIVVAAAPGAFVAPWINATTALVHMGYPGQEMGGAVADLLLQSATCISQGCPSGHLTFTMPNRFNETNMTMLQFPGLDHESNYTERLQVGYRWYNQHHLLPLFPFGHGLSYTSWGFEALGIGCNEQLECAASVTVSNIGPDTGRAVVQLYLTYPAAGLGQDEPPRQLRGYNTSLISPGSRTQIQFPLNARAFSAWDVGARAWTVQDGIFLLEVGLSVADIRATTSIMVAR
The following text describes a protein:
Function:
Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy. Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis. Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways. Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway through induction of RB1 expression. Plays a crucial role in muscular differentiation. Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis.
Subcellular Localization:
Cytoplasm, cytosol. Lysosome. Nucleus. Preautophagosomal structure.
Sequence:
MLYVFLVDTGTMLTFDMSLALQPVNVLQQEVARSLSVPADKQVMLISGGDMLESKSRVCSYSAGTDTNPIFLFSKVTIESAVPPSPSVDLGSDSDPRLQVEGCLNMPATYETVVARAQLALQFHDLAKDTVRSCEQLVHEQHLQQQGWAAVIANLEDCSSQFKIRVDSFEGLYSQYLVTRPKFMDIIQTFPNTIKLLEKIPLLPCLQGAPMQGIQSSGGVVTSRVFQPQTLLQWINAKDPSHTLEQLMEQCVRCMEQLDETVLQGLMAECNNILSSLNNPQMKEIKGLEDRLYGLEQLMAGTRKIVQEQGDMAQAFVQNQSRCSNLGDPSILPDLCASHRKQLLVMLNNHKQLRDIRRRCVIAKDELSANLHTRLRWIMYIEKAICELDSKLTIYYENIKRLKKRLEIVEQVSEAPTVYCQAVAETCRRRQFSEQFLQWAGNLSQDFTQLREEEVNRRKEFKNIFRKHFLKMMFPGMEDYPPGFATKPPDSFDKDLPFITQDDIQILQDTVPELSDSLRVPSPEELQQMSQHSSRFMHFSLTSHEPPLRDQKSQDSQATLVGPSRSSSETSACPQTTPTSEYSRSQSQDTISSKSSRNEELASVPEKEEGTQPPVAHTETPQVAEASHAPRPVPHRSAPPTNVTVRRMQQQQESGSYSPDSIDSHSVDLEYGSPTKRPVSDSFVSVNESPDEFMSATDVWQFQEGGYKSPPSSVGTPHESVESSVVETLGNTLVVKTEGAKVKSPSQSHTHLQRSLQERKSTIDMLERQLVSAQRDLAKSEDKCKKLHELHNKIQLQLKLGLVDLRQQVQDNRKDMSSHVALVTKQVFEVVSGLEKTMASEQEVAVQDAVGRVNEEKQALALDLEAKIQSEVSKCTKLNEEVQSLQEQLKERKVDEQNMTREWDIRVDNMKTEFEASQKALQERLEEEHKVKMNDMNETLAQKEQFVLELQREKEVMMEDIAERFNSEKGEVVMTLRKEYEEAKKQAVTELQEKLKVDHGKALAALKDEHDTHLKSACETIQHAMEQEKRGLEKQIKDLAEEVESLKAERDEEIERVRESMSEDKKTEVDMLISQLEIHKEKCEEALQECVAKEEEIAKMKEIFKIEKETAIKAAVDMEKEKAQSEIQKLKDKQDEELRDRENLVQTMKKSFEMEKKEVEQEVNMEKSRSLETVEGLKTQHEKELKEKQHTIEKLEKHFQEQKEELQKSVSEDQQKFEGEMEKLRTELERQLQQKDQELKLLRDIVEQEKSELMEKTISQEKHKHDSIVAEMQDNFDKQSKEKEDELTALQSRLQEAEGAKQTLEAEVAAVKEQQENAIAEIKASSTQQISSQESEITHLKQQLGELKKDKDDETNLAAGLKADLQRQLEVKETMISKMQAQQDSLIAEALEAEGQKLGAELDRLREEKLEESRIFEMQLEKLKESFELQKAAAVKEALVGVRQESIAGLSGAGSSEGAVTMAIGEERKKHEQELDSLKKSLENKMSSLKASLQAERQVAFNEAVSKVVAEKDSEIEALRQNHHKLMEAWGTDKEALEMAQSAIAAAVDERERALRLAQWREEELRALQADLDDANKKLEERSVVSERTPSIEQAMEAGDVEGATGMSVSTMSAITTISDSPGSDVQEDRIRTLEMTLRKKEEECMTLSQRLMQRSMSALGGPTEKVAIKDFQIGDIVLICLDERHDNYVVFTVGLVLYFLHSDSLPALDLKSAKAPGAPRKPWVLGQITDKEYCQAKKPQNRFKVPVGTKFYRVKAIPWGRKL