lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Auxiliary subunit of the mechanotransducer (MET) non-specific cation channel complex located at the tips of stereocilia of cochlear hair cells and that mediates sensory transduction in the auditory system. The MET complex is composed of two dimeric pore-forming ion-conducting transmembrane TMC (TMC1 or TMC2) subunits, and aided by several auxiliary proteins including LHFPL5, TMIE, CIB2/3 and TOMT, and the tip-link PCDH15. May contribute to the formation of the pore.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MAGRQHGSGRLWALGGAALGACLAGVATQLVEPSTAPPKPKPPPLTKETVVFWDMRLWHVVGIFSLFVLSIIITLCCVFNCRVPRTRKEIEARYLQRKAAKMYTDKLETVPPLNELTEIPGEDKKKKKKDSVDTVAIKVEEDEKNEAKKKGEK
The following text describes a protein:
Function:
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein.
Sequence:
MDRPNKSYPGGGYQGPNPAPHHYGSMEGTGQVNNPDCTASTSPAQIIPIEVEDELGENIYKMSPHVPISHDDTFKESSAIQGFAFMKTVSRLIYEYTHFAIYATLTLIIAPIMSFVWAIFFAIAHICVIWFSQPAIKMLYIFLRVCQLVYVPFVRFFLDPLYKSLSLVFSSIRGQFRLHSSDVTLNMKTIQV
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MRILPNISRATWFVGIFFVVNILLTACNQPSANSSAEPSPTETNSPVAQVTTDPYKDYKPRLNGKATVEMMVNGQPIIIEVDGENAPITAGNFVDLVEQGFYNGLTFHRVVDGFVAQGGDPKGDGTGGYVDKNTQRPRNIPLEIKVDPAVENAPETPVYSRALGNQAGFPVMLPHKTGAVAMARSQMPDSASSQFYFTLSDETGFLDGDYAVFGYVTQGMDVVLKIKQGDKIQSAKVITGQNNLEK
The following text describes a protein:
Function:
Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.
Subcellular Localization:
Nucleus.
Sequence:
MSSLRQSPLPTLQALSSSFTELNTILQPLLSHNYGSLNSALQSNSSSTKENTEDELHGRLDAARMQVSVAYVLLDLVWILLKTKGVDTKDHPVMQELERVKSYFGKIKSVQDKEKEPAGEQSVKVDRSAAGRFIRAALAGEPGTTQGKHTKFEEETPVKVKQTEETPKKTEAKEVKAAGSTPTSNKKKRPAMDPFEGYDKPKTIKTASATPTAKSTDSAASTPSKKHKKSKKTSASK
The following text describes a protein:
Function:
Does not exhibit calcium-activated chloride channel (CaCC) activity.
Miscellaneous:
MISCELLANEOUS: The term 'anoctamin' was coined because these channels are anion selective and have eight (OCT) transmembrane segments. There is some dissatisfaction in the field with the Ano nomenclature because it is not certain that all the members of this family are anion channels or have the 8-transmembrane topology.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Shows predominantly an intracellular localization with a weak expression in the cell membrane.
Sequence:
MAEAASGAGGTSLEGERGKRPPPEGEPAAPASGVLDKLFGKRLLQAGRYLVSHKAWMKTVPTENCDVLMTFPDTTDDHTLLWLLNHIRVGIPELIVQVRHHRHTRAYAFFVTATYESLLRGADELGLRKAVKAEFGGGTRGFSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSWVQAVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEADQTSRDVSCVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRRISPITRAEEFYYPPWKRLLFQLLVSLPLCLACLVCVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLALLVSVSAEGYKKLAIWLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFYLKDMERLKEMLATLLITRQFLQNVREVLQPHLYRRLGRGELGLRAVWELARALLGLLSLRRPAPRRLEPQADEGGGGGSGGGGRRCLSGGCGAPEEEEEAALVERRRAGEGGEEGDGPPGGKEEDEDDEEEEDEEEEEDEEEGEEGGLLDCGLRLKKVSFAERGAGRRRPGPSPEALLEEGSPTMVEKGLEPGVFTLAEEDDEAEGAPGSPEREPPAILFRRAGGEGRDQGPDGGPDPEPGSNSDSTRRQRRQNRSSWIDPPEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLIGQCGQLQRLFPWLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQHRYQQQQRRRREEEERQRHAEHHARREHDSGGREEARAEGSGLDPATSSEKASAKAKGSTAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAPSPSPSPSPQAVCWPSGWH
The following text describes a protein:
Function:
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.
Sequence:
MDSTSIMPRHRVGYWFSEKKSKKFNLEEFHGICDQAGLELVKINFTLPIEEQGPFSAIIHKMTDVIAQADLGDPECLTIVQSFERFICANPKIKIIDPFDNLRQLLDRYQTYSKINNSDLHKAGEVFVPPFVDLVSSDVDENIRKLREAGVRYPFVCKPAVAHGSKMAHQMSIIFHEGAVKDCEPPCVAQTFIPHDAVLFKIFVIGKKYFVVERPSLKNFSAAERPTIFFDSHDVSKPDSVSLLSILDDAEKSDVRPTTSGELLDKVISMLRFALEMNLFGVDIVVEKSTGHYAIIDINAFPGYEGVPDFFTHVTEVLKEIVESSPVSSSSSSVTTTSSSSSSGVGEEDSGIDTGDSSDEKRHQQNNQGSRVKRSSALFNSTSATIS
The following text describes a protein:
Function:
In the host plant, component of SCF(virF) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins such as the host VIP1, after its implication in T-DNA translocation to the host nucleus (By similarity). Required for the formation of tumors of a wild-type size on certain plant species only.
Subcellular Localization:
Host nucleus.
Sequence:
MRNSSLRDASGSNDAQVPHKTELLNLPDHVLTEVAKRLATNNPVESAENIANFSKSHRFTRDAVRTEPLEKFSSRLKILSRNAKLLSHAVRHAATLPDGEQLSEAQLSQMRSEVATRPVLGVAYTHQDGQPEERLSGNHLDHKINNIPNLVFNVAEPIMFNEISALEVMAEVRPIARSIKTAHDDARAELMSADRPRSTRGL
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MRLKLSVLEVCHTVLCIGLMLCGEGGVSSVLALGASIICRKMPGLSPRQRTICEARPDAMIAVGTGARLGTEECQYQFQHSRWNCTSLGEQSVFGQELKVGSRETAFYYAILSAGIAHSITNACSQGNLTYCGCDREKNGYRDPEKGWRWGGCSADVKHGIRFSREFLDAREVKRNARTLMNLHNNMVGRKLLEKNIRLECKCHGVSGSCTLKTCWVTLPHFREVGFALKDKYEKAVMVEAVRGRRQLVPTFLKLKIPQNNTKPAETDLVYVDRSPNFCEKDNTTGSIGTYGRFCNHTSTQTDSCELLCCGRGYKTFQYTRTWQCHCKFHWCCHVTCSTCSERTQAYTCN
The following text describes a protein:
Function:
Probable transcription factor involved in plant development.
Subcellular Localization:
Nucleus.
Sequence:
MVAMFQEDNGTSSVASSPLQVFSTMSLNRPTLLASSSPFHCLKDLKPEERGLYLIHLLLTCANHVASGSLQNANAALEQLSHLASPDGDTMQRIAAYFTEALANRILKSWPGLYKALNATQTRTNNVSEEIHVRRLFFEMFPILKVSYLLTNRAILEAMEGEKMVHVIDLDASEPAQWLALLQAFNSRPEGPPHLRITGVHHQKEVLEQMAHRLIEEAEKLDIPFQFNPVVSRLDCLNVEQLRVKTGEALAVSSVLQLHTFLASDDDLMRKNCALRFQNNPSGVDLQRVLMMSHGSAAEARENDMSNNNGYSPSGDSASSLPLPSSGRTDSFLNAIWGLSPKVMVVTEQDSDHNGSTLMERLLESLYTYAALFDCLETKVPRTSQDRIKVEKMLFGEEIKNIISCEGFERRERHEKLEKWSQRIDLAGFGNVPLSYYAMLQARRLLQGCGFDGYRIKEESGCAVICWQDRPLYSVSAWRCRK
The following text describes a protein:
Function:
Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endomembrane system; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MKNFLREHRNDYINATHLMYDTSRMTENERDRIDKEAQQFVFQCRELLKNLRKEVRNQSLTAQQLDHHEGVLFLLEGHLNSACNLYTEQKAIRVKKAYDRQKLSRLEPERKKAAVHDAEGGGEEVPWSQAENPPTAAPYGELPDLFSFDGWDENMVISYEEFQMFEQENKKLYEELNALSDEVRNIEGRVIEISQLQKVFTEKVLEQDEEMERIAHTLGGATENVKDGNEELRQAMKNNAGFRIYLLFFLLVLSFSLLFLDWYNP
The following text describes a protein:
Function:
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes (By similarity).
Subcellular Localization:
Nucleus, nucleoplasm.
Sequence:
MVQSCSAYGCKNRYHKDKNISFHKFPLARPDVCGKWVAAMRRNNFKPTRYSNICSQHFTKDCFKPECNNRVLKENAVPSLFCFSKLQIKAESLADPFPPEMDFPLTLPSLPLSDTEETQQEIQTETHHTVDPLPLVENLPHSMSISCDHNYTVEDTVQQKKRIEQLEEQLDKLRKKLKTVQQKCRRQERQLKRFKAIGEFQRVNRDPALGEGYVILPKQLYDALKGIEPVEGP
The following text describes a protein:
Function:
Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm. Nucleus.
Sequence:
MPYIDRLNRVCGFLDVEEKESSCRFQRRYFILDTKGNALLWYMDNPQNLPSGASSVGSLKLTYISKVSEVTAKQKPKTEFCFVINAVSRQYFLQANDVTDMKDWVAALNQASKITVPKYCPPPVRPDVTPEINVTHKGKRQQAYKTEIIGGVVVHTPIQNDAEETNGKERKGNRPGVLRCGYCVKQGNVRKSWKRRYFTLDDNAVCYYKSENDKEPLRAVPLREIQKVHECLVKSGDLLLRDNLFEIITSSRTFYIQADSPEEMHGWIRDIDSKIQEFRGPSRVPGSQFKRSSSLYRCPNASSASRRQPGDDRRPQLVKSCSVAPGWQPWTPVPVGEPSVMDTEEDEGSFSSLTTLISPSSSSSSTSSSSNSLTTPNPCLSTSPVPSSSGLGILTASADAASGRRRHRSQPQPPRSFPFSLDDDTIRTTDV
The following text describes a protein:
Function:
Necessary for the splicing of pre-mRNA.
Subcellular Localization:
Nucleus.
Sequence:
MLYCKQGVSVRVRRPTDYNPSLAAALGPGHPSPHLNLTAAGLMPGATGDAEEPDRIFVGGLPYLFTEVQIKELLESFGPLRRFEVVKDRETGNSKGYGFCTYQDPLVTDIACAALNGLKMGDKTLTVRRANSSSGQVKSEQECILAQARQHIAMQKMAFEAGGMTIPGTEIGPVVTAEIPTKVLCLTEVITPQELFDDVEYGEILEDMKEEGRKFGDLIDVVIPRPEPDHQIIEGHGKVFLEYSDVTGCSNAKAALGGRKFGGNTVIAIYYPEDKYYDKDYAA
The following text describes a protein:
Function:
UTP:RNA uridylyltransferase with a marked preference for uridine polymerization and a distributive activity for the first added nucleotides. Uridylates oligo(A)-tailed mRNAs to prevent 3' to 5' ribonucleotytic attacks. Reduces the accumulation of oligo(A)-tailed mRNAs. Prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis. Uridylation repairs deadenylated extremities to restore the size distribution observed for non-uridylated oligo(A) tails. Can prevent the 3' trimming of mRNAs still engaged on polysomes. Acts synergistically with HESO1 in unmethylated miRNA uridylation, leading to their degradation. URT1 and HESO1 prefer substrates with different 3' end nucleotides and act cooperatively to tail different forms of the same miRNAs. URT1 and HESO1 act sequentially, with URT1 mono-uridylating the miRNAs followed by their further uridylation by HESO1. URT1 and HESO1 are involved in the uridylation and clearance of RISC-generated 5' mRNA fragments. Has no effect on uridylation of heterochromatic siRNAs. Able to act on AGO1-bound miRNAs and the uridylated species stay associated with AGO1. Acts as post-transcriptional gene silencing (PTGS) suppressor.
Subcellular Localization:
Cytoplasm. Cytoplasm, P-body. Note=The P618L single amino acid substitutiontarget URT1 to the nucleoplasm.
Sequence:
MADGGAEPPAPPSSINAGEFLLSILHGSPSPSSQGPQHHQSFALDPAIAAIGPTVNNPFPPSNWQSNGHRPSNHNPPSWPLAFSPPHNLSPNFLGFPQFPPSPFTTNQFDGNQRVSPEDAYRLGFPGTTNPAIQSMVQQQQQQQLPPPQSETRKLVFGSFSGDATQSLNGLHNGNLKYDSNQHEQLMRHPQSTLSNSNMDPNLSHHRNHDLHEQRGGHSGRGNWGHIGNNGRGLKSTPPPPPPGFSSNQRGWDMSLGSKDDDRGMGRNHDQAMGEHSKVWNQSVDFSAEANRLRGLSIQNESKFNLSQQIDHPGPPKGASLHSVSAADAADSFSMLNKEARRGGERREELGQLSKAKREGNANSDEIEDFGEDIVKSLLLEDETGEKDANDGKKDSKTSREKESRVDNRGQRLLGQKARMVKMYMACRNDIHRYDATFIAIYKSLIPAEEELEKQRQLMAHLENLVAKEWPHAKLYLYGSCANSFGFPKSDIDVCLAIEGDDINKSEMLLKLAEILESDNLQNVQALTRARVPIVKLMDPVTGISCDICINNVLAVVNTKLLRDYAQIDVRLRQLAFIVKHWAKSRRVNETYQGTLSSYAYVLMCIHFLQQRRPPILPCLQEMEPTYSVRVDNIRCTYFDNVDRLRNFGSNNRETIAELVWGFFNYWAYAHDYAYNVVSVRTGSILGKREKDWTRRVGNDRHLICIEDPFETSHDLGRVVDKFSIRVLREEFERAARIMHQDPNPCAKLLEPYIPEDNNGQGHN
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.
Sequence:
MHGPDISDLDLPDLTLYPSTTGYSEQKRCFKQCVKDMSISYLNIDEESCSKNCLSKYLQAQIFLSQKMTNALTQLVTQDPSIKIAFKKPYKLPEQ
The following text describes a protein:
Function:
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Miscellaneous:
MISCELLANEOUS: Several bitter taste receptors are expressed in a single taste receptor cell.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MFLHTIKQRDIFTLIIIFFVEITMGILGNGFIALVNIVDWIKRRRISSVDKILTTLALTRLIYAWSMLIFILLFILGPHLIMRSEILTSMGVIWVVNNHFSIWLATCLGVFYFLKIANFSNSLFLYLKWRVKKVVLMIIVVSLIFLILNIFSLEIYDHFSIDVYEGNMSYSLGDSTHFPRIFLFANSSKVFLITNSSQVFLPINSLFMLIPFTVSLVAFFMLIFSLWKHHKKMEVNAKGPRDASTTAHIKALQTGLSFLLLYAIYLLFIVIGILSHKFMGGKLILIFDHICAIVFPISHSFVLILGNSKLRRSTLSVLRFLRCRSKHIHIMDP
The following text describes a protein:
Function:
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MPSSREIKRRIRSVKNVAQITRAMEMVSASKMRRAQRNVLATRPYADRMREVMANLTARVVGAARRGTLLEKRETVKSVALLVVTPDRGLCGSLVANVLRRAGRFITEQRAMGRTVDVYTFGRKGRDFFLRTGFAPAGEATRLGDAPKLEAILGVAISAINGFQSGKYDELYIIYSEFINTLVQRPAIKQLLPVESPDISTTTNVDYTYEPGEEEVLNSILPRYVETQIYQAVLESIASEHSARMVAMRNATNNAKDLVRDLTLSFNKARQAAITKEVSEIASGAAALTS
The following text describes a protein:
Function:
Lignin degradation and detoxification of lignin-derived products.
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MVQLLPALVALALLLVRPVADAAMAKYTFTVGSMQISQLCSSTSIIAVNGQLPGPSIEVNEGDDVVVKVVNNSPYNVTIHWHGVLQLMTPWADGPSMVTQCPIQPSSSYTYRFSVPGQEGTLWWHAHSSFLRATVYGAFIIRPRRGNAYPFPAPDKEVPIVLGEWWNRNVVDVESDAILAGQLPAQSDAFTVNGKTGLLYQCANETFTAVVEPSTRVLLRVVNAGLNSHLFFKLAGHNFTVVAVDAGYTSNLNTDTLVLAPGQTVDALVTTAAAPGSYYMAVLAHDTMSPLAFAASDTTTATAILQYNGTSSTNPPAMPAMPSSSDSGTANAFYFGLRGLGAPAVPAPVDVSMTIELGLGQLPCDPSQTRCNGTAAAAAMNGVSFRLPSPETSLLGAHVDGVAGVFTADFPDGPPPSGTAMSVGTKLKKLSYNSVVEIVLQNPAAVPTENHPIHLHGFNFFVLAQGMGTFAPGSVAYNLVDPVARNTIAVPGGGWAVIRFVANNPGMWFFHCHLDPHVPMGLGMVFQVDSGTTPGSTLPTPPGDWVGVCDAQHYAAAAAVAAAPVPVPAPAPVPAPILAPAPAESPLPPPRAVDHKPSPNLPQRREHTGTSNSAAGRRAKGHLACFLCSVLLFFLLRQHKA
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MDAQGSSSRALAGAGAGDGWPQPNWRVAYSYSSGSRGSSSSYSSTPGTTHSTPSPYSNTSGEGFTPSPQSFHGLDLMSYRGGGEGSKKKLEYIKYLLQEFCVAKGDVSILGSWLSEIMSVSRQIVAADASATSLMQFAGSWIRALTGITDSILAPYDCDTTTTSSCEIVVVGDGAPAGKLRPLIGVRGAVSRASQDIRLSFCSTSSEEAKRITDEMASLLLAKEARLDEAIWNTMEEVRTRLLASRDDDYSSWWGTQGIISPDIHKVTRAIVSYINILSTNCATVYMIVDQAVQIRGYVPKIHKCSPWASLIMETVSCLEEKLAEKSRSFPDQSMRFLFLINNSYFIWQQLYPTTASILESHMSDLARKIDNYIQTYLQVSWAPVLSCLSNSTPLCLGRSSSPAKFEAEFQKTYTAQKLWKVPDPKLRRRIRVAVIETVVPSFTKYLEYNDTNPSRITPEDLMDMLQELFEG
The following text describes a protein:
Function:
Required for initiation of gastrulation.
Sequence:
MDDNTAPKKNSEKKARVFDLQAMFAQTISNAPRTEEPTHVPQSVSVSSKSESGVSSSAVSDDEDDFMPDLPPGFQMQQSEAGPSSSRAEGPEDSDDSDFDETEAISIIKLIPAACEAKISHGTQAISALRVEPPGVRFASGGLDYYVKLFDFQKMDMSMRYDKELLPAESHVINSLAFSPNGETLVVASGEAIIRLLDRAGKQWSETVRGDQYIIDLNITKGHTATVNCVEFNPLNKNEFISCSDDGSLRLWNLDDHKVITKCINKHRKVIKTKGANGKRVSPQVCTFSPDGKWIAAGCDDGSVQAWKYGSQYVNVNYLVRKAHNGSITSIAFSPDSKRLLSRGFDDTLKMWSLDNPKEPLLVKTGLENAFKSTDCGFSPRAEVVFTGTSSPNKDTPGTLQFFDPMTFDLVYKIDYPGISCHRIQWHPRLNQIIAGLSDGTIHVYYDQTMSQRGVMSCVTKPLKRNRASEVVREDMVLSPLSLEMFQPRGEEGEEKEVTGWRIKKYLRMQDNKLRPEFRKPADMPINGKSANGRVAASGGSLHSYLAKQIGTARNAEFLKDTDVRASILKHAKDAEENPLYIDKAYRKTQPKKIFQETAVEPEDQDDEELQPVFKMPRTK
The following text describes a protein:
Function:
The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLTILKTGQSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSSAFWIFAALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNVGGGIVAPIVGAAFAILGSEHWQSASYIVPACVAVIFALIVLVLGKGSPRKEGLPSLEQMMPEEKVVLKTKNTAKAPENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKLFKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKLGWYGGFYLLMGGIVCCILFCYLSHRGALELERQRQNALHNQDSLQLADAQ
The following text describes a protein:
Function:
Acts as a magnesium transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MNEEYIDNVKHLIEQKDADKVKELLVDLHPADIAELCDDLNPEEARFVYRLLNNETAADVLVEMDEDVRKEFLEMIPSETIAKRFVDYMDTDDAVDLMRDLDEDKQEEILSHIEDIEQAGDIVDLLKYDENTAGGLMGTEMVVVNENWSMPECLKEMRQQAEELDEIYYVYVIDDDERLRGIFPLKKMITSPSVSKVKHVMQKDPISVHVDTSIDEVAQTIEKYDLVAIPVVDSIGRLIGQITVDDVMDEVREQSERDYQLASGLSQDVETDDNVLRQTTARLPWLLIGMIGGIGNSMILGNFDATFAAHPEMALYIPLIGGTGGNVGTQSSAIIVQGLANSSLDAKNTFKQVTKEAVVALINATIISLLVYTYNFIRFGATATVTYSVSISLFAVVMFASIFGTLVPMTLEKLKIDPAIATGPFIAITNDIIGMMLYMGITVLLS
The following text describes a protein:
Function:
Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.
Sequence:
MPSYKNMSLVRAGLRMVRQNRSGQSVIPSYRRYATSCKSPKGVVVGVYTKDGDKPSKTTANAVTLDDALGGKLLTLIRERGMDGTPGKGLLFSGFEGEYQAVAVVGVGKQGAAYNENEELDEGMENVRVAAGTGARALQLQGMYEVHVDSMDYPEQAAEGAALAVWRYNANKRKKNRIQTPKLDMYGKGDRDAWVRGLFKAESQNLARRLSDTPANMMTPSIFAQAAVDALCPCGVSVEVRSMDWIEDMNLNSFLMIAKGSCEPPLLLECSYCGTTPEDRPVLLLGQGLTFHSGGLCLKPKTGMDQYRGAMAGAAVCVGVLRAAAALSLPLNITAVMPLCEHMPSGMAVKCGDVVTLLNGTTMGIKNVDKAPVVQLADPLLYAQATYKPKLVIDIGTVAMGVNYAVGGGASGLWTTSKSVWQNFRKSGGLTGDRVWRFPLFKYYKQIVNKNITYDLCNTGRGPASSCLAAAILHTLVPCAEWAHLDIRGTGMTTTINPRPYLLKDSMTGRPTRTVIQFMYQMACSG
The following text describes a protein:
Function:
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
Subcellular Localization:
Nucleus. Chromosome. Note=Loaded onto the nucleosomes of condensing spermatids.
Sequence:
MSTSRKLKSHGMRRGKNRAPHKGVKRGGSKRKYRKGSLKSRKRCDDANRNYRSHL
The following text describes a protein:
Function:
Reduces the double bond in short-chain unsaturated carbonyls. Acts preferentially on alpha,beta-unsaturated ketones rather on alpha,beta-unsaturated aldehydes. Has no activity with (E)-2-hexenal and (E)-2-pentenal. Contributes to detoxify stromal reactive carbonyls produced under oxidative stress.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MNAALATTTATTPVLRRETPLLHYCSLTTKSPVYQINRVRFGSCVQTVSKKFLKISASSQSASAAVNVTADASIPKEMKAWVYSDYGGVDVLKLESNIVVPEIKEDQVLIKVVAAALNPVDAKRRQGKFKATDSPLPTVPGYDVAGVVVKVGSAVKDLKEGDEVYANVSEKALEGPKQFGSLAEYTAVEEKLLALKPKNIDFAQAAGLPLAIETADEGLVRTEFSAGKSILVLNGAGGVGSLVIQLAKHVYGASKVAATASTEKLELVRSLGADLAIDYTKENIEDLPDKYDVVFDAIGMCDKAVKVIKEGGKVVALTGAVTPPGFRFVVTSNGDVLKKLNPYIESGKVKPVVDPKGPFPFSRVADAFSYLETNHATGKVVVYPIP
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs. Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs.
Sequence:
METTDTHSEPDKLNINAPGRPVEKECNNVNQDTDCKNSATDVNINEKCSGEVEGGGTKDMDPEQAYAEGKISKKQLKRLRREEAWRKKKEFLKTKRKEQRRLEAQKRKEKGEPNKKRLRLEFEKRLETSDITISVDLSFDDLMMEQDIKKLMKQIERCYAVNKRAPVPVQMHLSSLGGRCRHRMETAIAGWQGWKVGMDSDLYTEVFERERIVYLTSDSPNTLSTLEPGKVYIIGGLVDHNSHKGLCYQRACEAGVGHAQLPIAQFVKIQSRKVLAVNHVFEIMLAYLELQDWQEAFLRVIPPRKGVEAITADQAGEVVTEIEKGEEPPNKGGPAVGEGNSALLDRDS
The following text describes a protein:
Function:
May play an important role during the early steps of organogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MYPSPVRHPGLNLNPQNYVPGPPQYSDFASYHHVPGINNDPHHGQPAAAWGSPYTPAKEDWHSYGTAAASAATNPGQFGFSPPDFNPMQPHAGSGLLPPAISSSVPQLSPNAQRRTPYEWMRRSIPSTSSSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAAALGLTERQVKIWFQNRRAKERKVNKKKLQQQSQPTSTTTPTPPAVGTPGPMGTLCSGSAPSLVSSSPLTIKEEFMP
The following text describes a protein:
Function:
Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endomembrane system; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MMDITSLFKASIKTVRTRNKALGLNNKPEDPNRIFPRSSKDLSKFQTKAKEIVSNVAKLKEFLTENRKAYLDTSVQLFNQVPKLSQADRAEFDHTTQLIIKTSNQYLQELKRENASQAHANAQTKEHRTIVISIIEQYFKSVCKTYSELKELYSKRQHELNKVTKLEGDGMASFRKSSLGYESPTDSPRVYSSYDDDDKKADEENVNFTVAEVQLFEKENSLLFNELNSLTEEVNQISGRVVKIAELQQVLTEKVLDQEKDIERIATTTVSATENIREGNEQLRQALQSNSGFRIAIIFFILVLFFSILFLDWYND
The following text describes a protein:
Function:
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MRSLHQPIRVASRCVPLPPSPPRSLPSPPPPPPPPRSVPAREATMAEVPSAALSQAGWYLSDEGIEACRSSPDKVNINDIILIALNTDLRTIGKKFLPSDINGGKVEKLEGPCVLQIQKIRNVAAPKDNEESQAAPRMLRLQMTDGHINCMAIEMNFMSKISLNTPPGTKIKLSGIVEVKNGFLLLNDSNTIVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCMSHIQVDSKELDQRKTLQVTIPIKPTSENDEFEKQRTAAIAEVAKSKETKTFGGGGGNARSNLNVSAGGNRNRETFQKEKISKPEGKHEGVYRELVDEKALKHIIEMGFSKEASRQALMDNGNNLEAALNFLLNGNKQKPSLGPPMRGKGKGRGRTRTEDEEELGNARPSAPSTLFDFLESKMGTLNMEESKSQSLPLHQVQHRVLNTEQNGFKDHNQPRHPFRNDMRQPRNEKPPRFQRDLQNSRQMLEAGGLPRSRGPERQNSLGPGVLTDERIRCDRPYPRNDRVKDLPYPTTSQQNDGAFKKRDNSMQNRLGKNPYLEAKENPIPQETIDLNNQARGKKENQMPNPDHFYDRKARTMSNETFSVVKNEKHFSMNSEYQNPIRTEGIMGVPNGEIEVLQKGRRMGPIKPTGPIMPAPFDDKMLYYISGPKRRSGPIKPEKVLESSFPAECGTIWKPGDECFALYWEDNKFYRAEIEALHSSGMTAVVKFCDYGNYEEVLLSNIRPIQAEAWMELPQCTFSHLREVMVNLGEVKGLRMDFECRPELATCVLFVFLLLCIPCPNPHPILAVHVTLSTSMPPSFPTHKYILFPSFLFDIPLHFLLVYLHLCWYVLPIRTYIPTSIGMCYPLGHIGRPFYYCQCPWTSLECMPMVPASCVMSFTITPLGRE
The following text describes a protein:
Function:
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by amyloid-beta peptides. Also protects against excitotoxic cell death. Prevents amyloid-beta peptide-induced spatial learning and memory impairments, protects against amyloid-beta peptide-induced suppression of hippocampal long-term potentiation, and inhibits amyloid-beta peptide-induced activation of STAT3 and inhibition of CASP3. Prevents glutamate-induced dendritic atrophy in hippocampal neurons and also prevents glutamate-induced decrease in SYP puncta number and total puncta area. Protects anterior pituitary cells from TNF-induced apoptosis. Plays a role in ovarian follicle development by acting as a cryoprotective factor for granulosa cells in the antral follicle. Increases androgen production in Leydig cells and promotes Leydig cell survival by preventing apoptosis.
Subcellular Localization:
Mitochondrion. Secreted. Cytoplasm. Note=Detected in the cytoplasm of anterior pituitary cells.
Sequence:
MAKRGFNCLLLSISEIDLPVKRLESPNKTRRPYGASIY