lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
APWLTVKMADGEGGSRLDGRARPQDAGEHSLCAMDSLLDTLGGLEDELRGQGVSETSTAEYCNRFCQALMQYAGSRNSVEHGLPLLEVYRLSIQSFAAVRPLLSCDSDSVALVLKRLALSCFELLLSVPDNEIPYDSWLQFHHTVQVAHNTLVEFGNTDLQALLRITSEGGAWKNAVLVSLFTAQPVDPEQVSKYIALEGAAFLEMRIKHLLNAGEVAKAMILAKICLENEHISNKTSLREMYISQLCSMMPSEEAIKEISSVDGKEVLDIICNLEADGQENNAFILCTTYLTQQLQQENIYCSWELTLFWSKLQKRIDPSLDSFLDRCRQFGLIAKTVYHLLFLVKVIQTEAEQLGLAASIELCVRALQIPQQDDAETKTSVCKMVACLLPDDLEVLRGCQLTEFLLSRSQEAYDSLEELYLKPDQKYDEENSIISNSLRCELLLALKAHWPFDPEFWDWKTLKRHCLKLLGLLSKQEQEEIECGSNAVTTDQRQETEDDQQLDQKQDRQPLKQVMKKKKEIGTSERYQRWLKYKFFCQICKREVIEARILHHSKMHLENGVFTCPVCLQKFQGKQEFMPHITEHIRMPARKNTHSQKKKKVKKKKVIKLEEDVDEEDMDDMEPGEIKLDPSLMMYYQSTADPDVLEQLLQQTKPSKPAEDDYITFSYIDTHFELQDRDVYPCPATDCTRNFKHFKYLSVHLKAEHAKDDDNIKHYLEMKDRREKCTFCRRHFFTAYHHRKHRRVHYGEQPYMCVAIGCGARFNTTNELVSHKQGHGYRLSYHCELKGCTLTFSDLGQLYHHEAQHFRDAAYSCVHPGCKKFYYSKKEFLKHLAVHGLTFTEEDFIAQRNMKRKPVDPFAEQEAVESIKKETESLPLSNTCTSTSQPSASKELTGTVTSVAVCFDGKRFTCGFEGCGRTYTLARDIQKHLKTVHPAQFKHEKKGQSLKKQSKEKSSKLKSIKQQGHQDQSARSHSSSQPIPTTSQKNSVPPSGDMDNSTSASPSSCIDDYLKDILLGFSQLSLNNTILPGSEVPCNSISGSSISQISSPPPSCASSPAKAVGKKVSSKPQADPCSVSKGQPPTQKSKAEASQSPSPSPQKDKHINQFLVQPTTKPFVCEVKGCSFRSVTSSALMVHYLKKHGFSKEKVKEMEIFKSSKFKPFRCHLCPRSFSKKSELRVHFISKHHLSENLVEQMSCSLKRRSESSKNLTANAPDPPDSGVYLKDTSRPEKKQCVKVQQNKGATDCTQKYQKNKQCTWLTEGKWEKGTKLEIKQEDKNKKDNAEEEDEEEEVTREGRGSRRLVAKNNLCYILTKYHKPFHCVHKGCSSAFTNQNGLIRHLQSVHRYNRSQLCLRFLCKHKGCGKHFHSSSGLARHYREFHRLNRETQDSTTPASEDPIPRFSCTYNDCTASYHLYSSLLRHLRHIHRDHGPQKTAPCQLRCSFEHSSYKQHVFYSHWDYYNSFVLRLQNDEKDKSASGCQKKLIIAGTQPLPRKTSPTPRLPLRQSLRNTSRSQDTPKEQTVKKESSSRRDRNLVFRTPEEALQMCQDRCFAVAYPCMLQDCDSVVTLEKSLRRHYVRCHRLSSTYVKLNYEKLVNNAEKLEELIQKKSALSTHSEVDRAPNGVLKVEYQAEPENHVGPKLPMSLHSIKTDPLDGQDPMGFGEESSENNLLVDADDLLYGEALKNGHSDRRERTLKNSHEEKPKLLATPPSSLRFTIDEGFLDYSGKGGGKGLGPLNNPSRQPLKRKNELEEPLPGPKDIQQSRLPHSPTSRTFDLTAYKPMGFESSFLKFIQESEDKEDEFEESGPWDSRHPEPQVVPRRRDLHRRSCSVKENSQSGLALARTRNCSLHGKLSAFKPRLSAGESATVKNLRSILDKALTDCGDLAIKQLHYLKPVVVLERSKFSTSLLDLFPTKKTD
The following text describes a protein:
Function:
Regulates senescence either by modulating WRKY53 or by activating SAG12. Affects the natural variation of cyst nematodes sex ratio and susceptibility to parasitic nematodes, depending on single nucleotide polymorphism (SNPs) between cultivars.
Subcellular Localization:
Nucleus.
Sequence:
MSEEFQESEVIFSDESFTRKDNKISHNNENYERKSTEKDKISSPVRIPSRTTIRYTEEEGEMTPPHVIIEKRRTEAQMAFSFCTLKGRDLSRHRNTVLRMTGFLEV
The following text describes a protein:
Function:
Gamma subunit of the CTDK-I complex, which hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit. CTDK-I phosphorylates 'Ser-5' if the CTD substrate is not phosphorylated at 'Ser-5', but will phosphorylate 'Ser-2' of a CTD substrate if 'Ser-5' is already phosphorylated. CTDK-I is also more reactive toward substrates that are prephosphorylated at 'Ser-2' or 'Ser-5' compared with an unphosphorylated CTD substrate, therefore efficiently creating doubly phosphorylated CTD repeats. Involved in RNA polymerase I transcription and RNA polymerase II transcriptional elongation, and as part of the CTDK-I complex, pre-mRNA 3'-end processing and SET2 mediated H3K36 methylation. Together with CTK2, required for CTK1 CTD kinase activation. Required for DNA damage induced transcription. Involved in the adaptation to alternative carbon sources, including galactose, glycerol and ethanol, but not raffinose. Required for the integrity of the rDNA locus.
Miscellaneous:
MISCELLANEOUS: Present with 2640 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus. Cytoplasm.
Sequence:
MDSLEARLQFIQVLKNLQKTLHKTRDSITSSSTTTPPSSQQKLNNDPIQFYLRNYRHHYEDFHQCLFDTTMKMDPLDRLDVVIYYVRIIRNLYPHSHSNTNVTKVLNEVLLMDIDLVFELCLPCQDWKSLTNQATCKELFLDLSKLIHYDATSVTHTPSDTTLIDATTWYSVKTERTTKDYKESLQRTESLLKDRDLKKLAFFQQFNSDTTAINPDLQTQPTNANILLHRMEADRELHKRSKETSWYIERPSNDILDESEFKSLWTHFETTDSGFDKDDYKNIKALNDIAKASYIY
The following text describes a protein:
Function:
Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system (Probable).
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGSLTIDGVDHTTMPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAVQQGKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELLSGKASASALLGITG
The following text describes a protein:
Function:
Plays a role in controlling the transcriptional activity of MyoD, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity).
Subcellular Localization:
Nucleus.
Domain:
Lacks a classic transcription activation domain and instead possesses an N-terminal region capable of inhibiting heterologous activators.
Sequence:
MKTKNRPPRRRTPMQDAEATPGEQTPDRSQSGSGASEVTKGLRSRTARASGTRAEVSRRRQGSSSRRENSVQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTMSSSRLPGLEAPGPAPGPKLYQHYHHQQQQQQQQQQVAGAVLGVTEDQPQGHLQRYSTQIHSFREGS
The following text describes a protein:
Function:
Involved in mitotic spindle assembly checkpoint signaling, a process that delays anaphase until chromosomes are bioriented on the spindle, and in the repair of incorrect mitotic kinetochore-spindle microtubule attachments. Phosphorylates MAD1L1 to promote the mitotic spindle assembly checkpoint. Phosphorylates CDCA8/Borealin leading to enhanced AURKB activity at the kinetochore. Phosphorylates SKA3 at 'Ser-34' leading to dissociation of the SKA complex from microtubules and destabilization of microtubule-kinetochore attachments. Phosphorylates KNL1, KNTC1 and autophosphorylates. Phosphorylates MCRS1 which enhances recruitment of KIF2A to the minus end of spindle microtubules and promotes chromosome alignment.
Sequence:
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQTSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKTESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQKHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQLSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGESHNSSSSKTFEKKRGKK
The following text describes a protein:
Function:
Co-chaperone that regulates stress responses (Probable). Acts as a negative regulator of saline-alkaline stress tolerance. May participate in stress response through regulating the homeostasis of iron, manganese and zinc ions.
Subcellular Localization:
Mitochondrion.
Sequence:
MGSYHYTSTSHFFFAGGGEGEYSSYKGTGSTDTHRPTTVRIPVTTPGPERPPDDAAAARIQAAFRGHLVRRHAAAVRGADDEATRLERLLRRQETVDAVRGDERERARFSEALMAVLLRLDAVPGYYPAVREARRAVTRRVVGLQEVFDAVLAAPDAADTCGVPASLDQVLEGIWGESPAAPPPPPPPPPPAAVEVEEEVVRSPCWRRFFGGV
The following text describes a protein:
Function:
Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
Subcellular Localization:
Cytoplasm.
Sequence:
MHCAILKAEAVDGAHLMQIFWHDGAESLYPAVWLRDNCQCSDCYLHSAKARKLLLEALDVNIRIDDLTFDRKKVYITWPNDHYSEFEANWLKKRCFSQQARARLQGELFLPECQYWGSELQLPTLNFEDVLNDDDHAYKWLSSLKKVGIVRLTGAADKRGEIIKLGKRIGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKEKNPQAFHILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRVNFNNATRDTVFDVPIERVQPFYAALKEFVDLMNSKEYKYTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVTNGN
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MGKQLKKGRAPPGGNQFSKKVAKQSAETVMEQRSCVHFDKCVDLNKLLKKMKACERIKCRDCKEGVDMKRRSEGEVSSFSCDAAKRAVWLCLECGRYCCGGVGLPTEPQSHVMRHIKMTCHRLVIQCENTRLRWCFACQSLLPFEKEVNDSRSSSSISGEIKGSGYGVRGLVNLGNTCFFNSVLQNLLSLDRLRDRLFKEDQSCGGPLVSSLKKLFTEAASEAGLFNSVINPWDFFGTLCSKAPQFRGYQQHDSHELLRCLLDGLSIEETSLRKKHDGDESEKPTLVDSVFGGEVSSTISCLECGHSSKVYEPFLDLSLPVPSKKQTLSQEERSKLTPPTKVFKNVEDSKDSSEPVSTMTFDNNQVPEIIVTQKEMEEVGKVSHNETDLVSQGGVSDNDDGSAKQKDKEAITHSTETLMPDNDGSAKPDKEAMQFAEDKGETSSSYVSGHHDQQTVDYVDFSWFFEEPDVAFDDKTVRESGFMGVSSNSDAEVVLDDLDSPVSVESCLAMFTKPEILSEDNAWHCENCSTNLKLQRLREKRELVGSGWVYDTIFNQSFTDFKNWDTIYDDEAVDSEEVVVRSAAIKRVLVNKAPPVLTIHLKRFSQNARGRLSKLRGHVAFNEFIDLGLYMDMEQDEEDQPVYMLAGLVEHSGTMGRGHYVAYIRGDDKERRDSSVWYRASDYFVRQVSFEEVLRSEAYILFYQLI
The following text describes a protein:
Function:
Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Subcellular Localization:
Chromosome.
Sequence:
MPTLRKRKSTSPGNPAANKGRQSKTRTPKRRKVTKTNFFVDGDVDENERVTASEDEINDEEYTPASQKKGKNNRAKNLTSPRKRSLNKTEDSTPVAKRKRRSTAKKVLNVEHDASIFAAVLSGQAMQMTIDDWITHYNQNNKKGLIELVQFIVHCCGCKGVVTEEMLKESENIKSIQELTLKFDEDSNEYPIIMTGPKYKKLKGYLRDFIVQFVAACQNDIIYDDDVMVVVVSWLIRLADSQVRAFRHTSTFLGMHLGNGLITVITTVKRELEVSQLKENVSFLENLLKNILTGVFVHRYRDINPQIRTLCIEQLGNWIRYYSPLFLNDNCMKYIGWTLNDKVSSVRIAAVKVLQELYSVANFSSQLNIFTKRFCERMIIMTSDKECDVCVESIKLMTILLRYEDILDDVACAQVYRLVFCSNPNISHAAGEFLSTWLFSGDNDTEKDDGVSTDLMKKKAKIRMMKDLIRFFIDTEVHELADYLVDSLWNSTELLKDWEIMTGMLLGQHLKEDEEPLDDEEEFRLIKIMCCAIKQGSVGHGPPGRQMGKKGFISSKEKRAQRSLKDGISTHFSFILPKLLAKVLEALLKQIEGILDKHTDMEVLDVCAKTLRCLLGEESNVKTAVEVTRHKIMDRVTDEFKEIFGGTGGKEAINDNVERALSECDHDTEINMLTYLRKIIVMHKEFNIKAWECIPYFNAVVDYGLRKSINDEMLCLAMSGVQLSLAWEFSDDEAEGGQLKTGPLLENFNHLLRMCDELMQFGNSIVQKKVFCILCDTLMMVSKPLMESDPATILAYETDRSIQIRCRDFIVSCVFDVDEDFDLESRKDDVPDSDYEMFCEKRNLLAAFCKLIVYKIFDTELAAPVFANYLKAFESVKFENLASPSSVLKDIEPLKELARRFGLTFGVESLKSQSTRQNLINLHRDGIKYALEKSDDVPTYPRLPFLVILNEFSCRLLDVDKSSKTAGVRSPDVAIIDVITSLTIRLPFLEDLLPSELKSNMRNEELYPLRIYFEGLKGEKNNAEEAADIEDDKDDKADSEPVEEPQEDEWLSKDKAVKEQKGKRKSKGRRSMRSSGRTAARQSNNSINNSNDTTSKDRSMDVEDSQKGAKVKKGKEVKTKDNSGKHDESEIAESISKEAVESESSDSESDYIDAPDSQESWLASQPKEKKSSRKIRYNYSKLMEKA
The following text describes a protein:
Function:
RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.
Sequence:
MSLLSAASPETGRRDHDERTSSNSGNVEIHTLSGGREISGHKHSNPCISSPDPLATSKLGNLQSPVGQKNDNASNKKQKLEHTSNTLPLTGNSEMERLLAKLSPKPQLSDSKQTINQDILSKLSEQQLLLDQQKSILAKNKVVGPGHLEERDKPLTMPQRMDAKQAASPKEVARFEAFDTEGSELLRLKRELQAANSKIALQEQELAQTRVIKHTLDQALGPPSEADFSGRDISEQTISNLQSAFNASIPAPHLLQDGWNTQEDSQSDISDALSAGAYNRSRGFWGPPAQQVYGVGLNSDKAYADSNMPLPGTAFGHDSSRFWGPSNTNPSIPANSSFQPHRVLSGPSTAPCSFDGPFSDDQVDKIVCNNDQQASIFLQQKLKVGTTEQKFDIIEAIIQQAYSLMVNRFGNFLVQRCFEHGTSEQIVAIANAIKGNTLSLSMDPFGCHVVQKAFDCVPEEHKAVMVHELLRRIPETVIHRYACHVWQKLFELRWSGEPPQIMAKVNEALRGMWHEVALGETGSLVVQNIFENCVEDEKRPAIEEVLAKIDVLAHGQFGNWCIQHICEHGAPHDKSRAIEHILLWVVDYSMDQFASKIVEKCLKIGGSEFLDRYLSRVCTGRTDRPRMPLIDIAGDQYGNYLIQWILMNAAPHQRELVATHIRHPINMGVASAEEASGIPATPLFVKRLTNQVSQDLKHLEKYEPARPTQDIDSILDVICVHECPANQTSSFPDLHGCTRLKKLDILCLVLISYTHLVELLGSLLFILSIVRAPHVLLQGSRWRYSDGSTECLRQWSVCGTAL
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MASYVTCPFLIEKRKRNICTGYYNSTTPPEFKTPTNVSFLSSAMERDFLGLKRKDSSGTLTEITSNNIFNDSALTKKEHVDFPKLRLSWRKNLFYFVGGMQRWWSEDSSWSQFQPFGATRDDTPDTLASPVYAFDFTCNPLSTLPKRSFNSTTPWKFPFQEETIPTSKQFLGGFPFAERSATSSPTDPRNKSKQVEAADDRLTIVYDNKVHVFEDISPNKAEAILRLARDEYYSFLTADDDRNQVVLPEQTTMDLLCWTSNGNQHALDPPSIINSSAEFDSHTYSAITLPQARKATLEHFLEKRKDRLTNGMFYKFMKTVLYSPELLR
The following text describes a protein:
Function:
Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSYKTRKEVLPRSEIEALIADGHHIVIYNGKVLKLDNWLDRHPGGDMAIFHVVGRDATDEINAYHSDEALATMGAYQIGITGEKIWENFLPPIQGGVFRKRGSIAADEGISLSSSASSSSQEAVTQKPAPIFTNEQILKAERLKLIEEDENRQLQHDLEIFPSLDYNTQTEIGTKYKALYKRVEDAGLFEPNYRGYFSDFLRISTMFSLSWYLFDKSMFLSAICLGMGWHQLVFIAHDAGHIGITHGYQMDNWIGMTIAAWIGGLSLGWWKRNHNVHHIITNDPVHDPDIQHLPVFAVSNRFFSSVKSTYYNCVLKYDIFARYLIPLQHMTYYPILCLGRFNLYALSWGHVLLGRGPRHGKAAWFRWYELMGLSFFAYWFFYLIVYKSIPTAGQRWMYVIVSHVATMPVHVQITLSHFAMSTQDLGLSESFAQRQLRTTMDVDCPAWLDFLHGGLQFQAIHHLFPRMPRHNLRRAQRYVLEYCKDIGVEYHIYGFVHGNQHVIGKLGEIAKQAEIFRDCERHLREEHVAEMTEAK
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MEQFEIIRESDADPYYFNKNLRLEECEIDGFTSIYKAPPPYSFVAGLSKNTSSNSFVIHKCLPPLQRNNTIRKRKRNPFLADRPYCINSEDMPLSDDRDMLKERHVKSRKLLLKEKGNRFYRRS
The following text describes a protein:
Function:
Ferric chelate reductase involved in iron uptake by shoot and leaf cells. May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDDYETPLLSKDSSSSSSVITSSLKWILKVVMSMIFVTWVVFLMMMYPEQLGDDFLTFVSSKTFLGTTGTMFLIFSCPILVISVLASLYLIISGEDKVFTKKKISKFPRFRLWTFPVLVDGPFGVVSAAEFLGIMVFSVFFLWSIYAYTLRNLDLLERFHVLPKNRSILLLEVTGLRLGMIGLLCMVFLFLPISRGSILLRLIDIPFEHATRYHVWLGHITMAFFSLHGLCYVVGWIIQGQLLELIFSWNAIGIAILPGVISLVAGLLMWVTSLHTVRKNYFELFFYTHQLYIVFIVFLALHVGDYMFSIVAGGIFLFILDRFLRFCQSRRTVDVISAKSLPCGTLELVLSKPPNMRYNALSFIFLQVRELSWLQWHPFSVSSSPLDGNHHVAVLIKVLGGWTAKLRDQLSNLYEAENQDQLISPQSYPKITTCVEGPYGHESPYHLAYENLVLVAGGIGITPFFAILSDILHRKRDGKACLPSKVLVVWAIKNSDELSLLSAIDIPSICPFFSKKLNLEIHIYITRQSEPRLEDGMVHKVVHPSVKLPRTNGCSMSVLVGTGDNIWSGLYLIISTIGFISMITLLDIFYIKRYNITTWWYKGLLFVGCMVASVLIFGGLVVVFWHRWEHKTGEVEANGNDKVDLNGEETHNPSAAELKGLAIEEDVQNYTTIRYGTRPAFREIFESLNGKWGSVDVGVIVCGPATLQTTVAKEIRSHSIWRSANHPLFHFNSHSFDL
The following text describes a protein:
Function:
Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Acts late in the proteolytic pathway in conjunction with the 26S proteasome. Plays a role in avoiding DNA overreplication (By similarity).
Subcellular Localization:
Cytoplasm. Endosome.
Sequence:
MSDDYFDRLFELAFVYINEDETIQSCSFRGQRWLEEAQTLEQKNSLLKAYYYYLKALKLAYEIPCRFEISVKSTHYGEFKQFQKLAIQAVSKAFTIKSKLAVKHYLPVIQISDALSLSKKSSLKVLFLNFYSQESSKGYVFSKHTIAIPISCLQSMDSSKIYDFLKSAPFHPSMVICYSLERYFEDVSLAYKLYSMLRSLKLDPHFMELANPKKVDSSLSYENYQPIGLTNLGNTCYMNCVLQCLFACKDLTIPMLQGRGLLQNINTKNPLGTGGKITSAFFSLLQSVLLNHGQRSISPRNFLEIVQSLNRDFSIDGQCDAQEFLNFFLDKLHEDLNSNASRSPIAPLTEDQLSAREELPLSHFSHIEWNLHLRSNKSIVVNNFVGQLCSRTQCMTCGRTSTTFAPFTSLAIPIDDVSHVVSLQECLLKFSAPELLQGHDGWHCPVCKVQRSAKKVIMISKLPEYLIIQIQRFKISVMGRKKIDTPLGLSLQIPSKMLVPPSFQSGIGYIPSNYNLFAFICHYGQLENGHYISDVLFNNEWCHIDDSIVRTVGGITDLREDFSSSYILFYKRSSLLEEFEDKCPKMTLKRNVK
The following text describes a protein:
Function:
Component of the 40S subunit of the ribosome.
Subcellular Localization:
Cytoplasm.
Sequence:
MVKFVLSGHHKKTLILPSSNTLPYPAKTRCSALLCISPSENPKKEAKMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGAKKRKKKTYTKPKKIKHKKKKVKLAVLQFYKVDDSGKVQRLRKECPNAECGAGTFMANHFDRHYCGKCGLTYVYQKAGGD
The following text describes a protein:
Function:
Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGVTGTPSYYSDKNCTIENFKRDFYPIIYLIIFVWGALGNGFSIYVFLQTYKKSTSVNVFMLNLAISDFLFISTLPFRADYNFRGSDWIFGDWACRIMSYSLYVNMYTSIYFLTVLSIVRFLATAHPFQMLHITSVRSAWILCGIIWVFIMASSGLLLKHGQEKKNNTTLCFELNLQKFKNLVILNYIALGVGFLLPFFILTICYLLIIRVLLKVEIPESGPRDAQRKALTTIVIAMIIFLLCFLPYHALRTIHLVTWDADSCMDELHKATVITLTLAAANSCFNPFLYYFAGENFKARLRAIFSKDHL
The following text describes a protein:
Function:
[Cytochrome b-c1 complex subunit Rieske, mitochondrial]: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. The Rieske protein is a catalytic core subunit containing a [2Fe-2S] iron-sulfur cluster. It cycles between 2 conformational states during catalysis to transfer electrons from the quinol bound in the Q(0) site in cytochrome b to cytochrome c1. Incorporation of UQCRFS1 is the penultimate step in complex III assembly; [Cytochrome b-c1 complex subunit 9]: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII). UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer. One of the fragments, called subunit 9, corresponds to its mitochondrial targeting sequence (MTS). The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function.
Miscellaneous:
MISCELLANEOUS: The Rieske protein is a high potential 2Fe-2S protein.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MLSVAARSGPFAPVLSATSRGVAGALRPLLQGAVPAASEPPVLDVKRPFLCRESLSGQAAARPLVATVGLNVPASVRFSHTDVKVPDFSDYRRAEVLDSTKSSKESSEARKGFSYLVTATTTVGVAYAAKNVVSQFVSSMSASADVLAMSKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTKKEIDQEAAVEVSQLRDPQHDLDRVKKPEWVILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPAYEFTSDDVVVVG
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MSNQFNTRKRLMAMLANEMRLEQEENAIAKQSAKFHSKFATTMENIKRQQHESKKLNTLLNQRRDEVEKRNALKNAVRDKLAEEEQHCAEMQAQLGKKKQERDKLIACAHILSEAANTYINRKALPERVKGVAVSPDNGQWIPFDFNAHDRQGLAALWTQVNRSSRNINKWRQLSSVGNSSMPAPSGKENANVSMTSVIEIDLTSPPSQK
The following text describes a protein:
Function:
GTPase that plays an essential role in the late steps of ribosome biogenesis.
Sequence:
MFTVAIIGRTNVGKSTLFNRLIQKPMAIVSDTPNTTRDRIFGIGEWLKRKIAFIDTGGLIAKQTPLQQLIALQVQAALSQAKAIIFLVSLQEQLNSDDFYVAKVLKKNKDKPVILVVNKAENFNPKTAEETLKDYYSLGFGRPVVISAAHGIGIGDLMDLLVKQNQLLPNENNDDLAKIRFCVIGKPNVGKSSLINQLVKQNRVLVSNESGTTRDAIDVPLKVNGEKFLLIDTAGIKRKGKINMGIETASYIKTKLAIARSNVILLMVDGSKPISEQDEVIGGLAQAALIPVIILVNKWDLVLKNNNTTNAYKKMLKLHFKHLDFAPVLFISVLKNQRLNTIFEQLKIIQSQLETKVATPLLNDVIQQAQLYNQPPLFKGKRLQITYAVQTKSQIPHFVLFCNDPKYLHFSYARFLENKIRENFGFNSVPISLYFKSKNARIRTKPEV
The following text describes a protein:
Function:
Probable methyltransferase.
Sequence:
MDDLKTISSNCIVKNSKDQGNYVVASKDIKAGDFIVFREKPYSCCINFKIEENEKKICHYCFTINNNNNLNNNIHNMHTDNFIICNNCKLNWYCSEKCKNEDYQTSHQYECKIWKKIQSASQFNNECKTTIKLLIKILILQYNEIKINNNNDNNDNNNSYKEIKFKDIIGLESNSNKFSTQRITDFMKISKFIEKSVDKEIIDTIYPTVKEMSLFQKNMIKLMCILECNSHDISFPFRTNSSITTFNYYSIGIGIYFNSSLFNHSCQPNICKVIESCKNNFGCHSMVAIRDIKENEEISFNYIQLNQNKQERIEKLQSSYYFTCNCPSCCTNNPNPHKEFLNKYKCKKLNCSGLEYPNNNNNNNNNLICNICLPINFN
The following text describes a protein:
Function:
Transcriptional repressor which binds to the consensus sequence 5'-GCCTCGA[G/A]G[C/A]-3'. Represses CLN1 transcription.
Miscellaneous:
MISCELLANEOUS: Present with 195 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MKYPAFSINSDTVHLTDNPLDDYQRLYLVSVLDRDSPPASFSAGLNIRKVNYKSSIAAQFTHPNFIISARDAGNGEEAAAQNVLNCFEYQFPNLQTIQSLVHEQTLLSQLASSATPHSALHLHDKNILMGKIILPSRSNKTPVSASPTKQEKKALSTASRENATSSLTKNQQFKLTKMDHNLINDKLINPNNCVIWSHDSGYVFMTGIWRLYQDVMKGLINLPRGDSVSTSQQQFFCKAEFEKILSFCFYNHSSFTSEESSSVLLSSSTSSPPKRRTSTGSTFLDANASSSSTSSTQANNYIDFHWNNIKPELRDLICQSYKDFLINELGPDQIDLPNLNPANFTKRIRGGYIKIQGTWLPMEISRLLCLRFCFPIRYFLVPIFGPDFPKDCESWYLAHQNVTFASSTTGAGAATAATAAANTSTNFTSTAVARPRQKPRPRPRQRSTSMSHSKAQKLVIEDALPSFDSFVENLGLSSNDKNFIKKNSKRQKSSTYTSQTSSPIGPRDPTVQILSNLASFYNTHGHRYSYPGNIYIPQQRYSLPPPNQLSSPQRQLNYTYDHIHPVPSQYQSPRHYNVPSSPIAPAPPTFPQPYGDDHYHFLKYASEVYKQQNQRPAHNTNTNMDTSFSPRANNSLNNFKFKTNSKQ
The following text describes a protein:
Function:
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Subcellular Localization:
Mitochondrion.
Sequence:
MLSYTSCAKLICSRYIVSKISFYSLKRCNSTAVVRTRFAPSPTGFLHLGSLRTALFNYLWAKKSNGKFILRLEDTDQKRKVTGSDLEIYKVLKQFNLQWDEGPIVGGPYGPYEQSSRLQIYQKYAQHLIETGRAYVSYSVPIATTKIDSSTKYHEISIDDLTDAQRKLYKSKKFPYVVRFRMKEPSPFTDLVYGKIAIKSDSREIEESNNFVILKSDGFPTYHFANVVDDHLMHITHVIRGEEWVPSTIKHIQLYEAFGWKPPKFAHLPLLVNPDGSKLSKRQNDAHVSSLLQEGFLPEAILNFIALMGWSSRQKSDFLPMKELIDLFSIDKLTKSSSIVAFEKLYFLNKNYLRRAISDVNRLDELIELVQPRLIQKFSHSSRSHDKSYTKKLLLLLKNKVHTIKEFEKIVFYFYEASDLQQIRSLVSSLITVEELPKILTTILNKFETIEWNTHEIQISLKEIAMEHQMPLKKIQSLLRYGLCGNLPGGGISDTISLLGKETVKSRLERLLLSLKHELPKRSCIV