lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the regulation of root growth. May regulate sorting and/or transportation of trans-Golgi network (TGN) vesicles in root cap peripheral cells, thus influencing the extracellular secretion of mucilage components in the root cap.
Subcellular Localization:
Golgi apparatus, trans-Golgi network.
Sequence:
MLREMLGCCKVYISEARNKTALEAIERALKPFPPAAIVNKFEDAAYGRVGYTVVSSLANGSSSSLKNAVFAMVKTALDTINLELHCGSHPRLGVVDHICFHPLSQTSIEQVSSVANSLAMDIGSILRVPTYLYGAAEKEQCTLDSIRRKLGYFKANREGHEWAGGFDLEMVPLKPDAGPQEVSKAKGVVAVGACGWVSNYNVPVMSNDLKAVRRIARKTSERGGGLASVQTMALVHGEGVIEVACNLLNPSQVGGDEVQGLIERLGREEGLLVGKGYYTDYTPDQIVERYMDLLNNS
The following text describes a protein:
Function:
Secreted proximal epididymal protein required for post-testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pellucida. Does not have ribonuclease activity (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MKLTLVQIFFMMLLLLLGLGVGLGLGLQMAAAVLEESDQLLDEFLSSDSQDKAEATKEGLDSQSTETLLVSNKVVPPEDTIVNEDDVGGDRMLRAEVLSQSNKHYLRSDVMDRECNALMAPNLKSKDHPCIPQYVFIHEEPDTVKAVCKSPAVACDLKEGKCHKSPRPFDLTFCKLSKSGQVIPHCNYVTFILEKYILMSCSDMKVQITSKS
The following text describes a protein:
Function:
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
Sequence:
MIKVEIDEGSGFCFGVVTAIHKAEEELAKGETLYCLGDIVHNSREVERLKAMGLITINRDEFRQLRNAKVLLRAHGEPPETYQIAHKNNIEIIDATCPVVLRLQKRIKQEFRKEDFEEKQIVIYGKNGHAEVLGLVGQTGGQAIVIESAEEAKKLDFTKSIRLFSQTTKSLDEFQEIVEYIKLHISPDATFEYYDTICRQVANRMPNLREFAATHDLIFFVSGKKSSNGKMLFEECLKVNANSHLIDNEKEIDPTLLRNVKSIGVCGATSTPKWLMEKIHDHIQLLIKD
The following text describes a protein:
Function:
May be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MNSMTSAVPVANSVLVVAPHNGYPVTPGIMSHVPLYPNSQPQVHLVPGNPPSLVSNVNGQPVQKALKEGKTLGAIQIIIGLAHIGLGSIMATVLVGEYLSISFYGGFPFWGGLWFIISGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAYPDYYPYAWGVNPGMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSVIYPNIYAANPVITPEPVTSPPSYSSEIQANK
The following text describes a protein:
Function:
Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MPDDWKKDAYPEPPNRTPAADKQTALPNPAVIVGKLFNYAVDAPVTLFHDWVERQRLKNKYNYYHREYRRVPYLTECEVGDYLCYYEAEMQWKRDYKVDQEIVKVLQERMRACQQREGHSYIQNCAKEVAQFTEAAKGYQSRYGDLGAYGNARKCLMKQKHRMISERKAEAQDS
The following text describes a protein:
Function:
May have microtubule-stabilizing activity.
Subcellular Localization:
Golgi apparatus. Cytoplasm, cytoskeleton. Note=According to PubMed:16837464, it colocalizes with microtubules.
Sequence:
MAWPCISRLCCLARRWNQLDRSDVAVPLTLHGYSDPGSEESGADCSVSRGNPSVAGARESSRAVPLTQYQRDFGVRTARAGSRDAAQERPSGPGGRRGQSSAPPTRTVYVLPVGDADAAVVATTSYRQEFQAWTGVKPSRSTKARTARVVTTHSSGWDPSPGASFQVPEVRKFTPNPSAIFQTSAPQTLNV
The following text describes a protein:
Function:
Component of the trimeric PUCH (precursor of 21U RNA 5'-end cleavage holoenzyme) complex, that acts as an endoribonuclease processing the 5'-end of precursor Piwi-interacting RNAs (piRNAs). The PUCH complex consists of tofu-1, tofu-2 and either slfl-3 or slfl-4, with tofu-2 exhibiting endoribonuclease activity. PUCH-mediated processing strictly requires a 7-methyl-G cap (m7 G-cap) and an uracil at position three (U3). PUCH also exhibits a strict bias for piRNA precursors with an A or G at position 1. Mature piRNA production is enhanced by the interaction of PUCH with the PETISCO complex, which is stabilizing piRNA precursors and allows their processing by PUCH.
Subcellular Localization:
Cytoplasm. Mitochondrion. Note=The localization to the mitochondrion is mediated by slfl-3.
Domain:
In mammalian Schlafen proteins, two SLFN-folds come together to form the nuclease domain. In tofu-1 and tofu-2, only one SLFN-like fold can be identified, suggesting that the two proteins may interact via their SLFN-like folds to form a functional nuclease.
Sequence:
MADTSPRESKLNKQDQDLHLEIDETGLACKSEVKKRWLGARGTAGLYGNGKYYYEVTITSKGLCRVGWATLGGSLNIGKGLDSFGYGGTGMKSTHKKFDDYGLPFTLNDVIGCYLDLDSRTIWWSKNGEQFPAAFSIDVKYKNSNTCLFPAVLCQNSSLSVNFGSQPFKFPPGNQFTAVSDAPNENVNWWSYEEQNSFEHVVVKLPFAVEEDVHNEFRMHTKLMLTELKRTQCKQDKDGSIRRTLQPISKTICAFLNTDGGRLFLGVNDDKVIKGISMSKNMIYHFFGSLRHMCENFKPCSPLCRIKVSILEVIPVGVIKVKLRKADLLKEEAHDFPKLACHSVGGSFCDCFLEINKAPTKQYLLIIQVSPPNPNSRTTIFQNEEGLVYRRRMASNKCVYLDDLRRMMNEKNQVFVDLPDEARAEIDSFSKFD
The following text describes a protein:
Function:
May regulate endocytosis in response to extracellular stimuli.
Sequence:
MYIPNLRNYHDKVFPYGPSSNGYNPVIRLTDRTTQPDPSQHIYQEEKISKCEGLSYRAREWLLLSSNSNARVAIALAEPVLYLPGATSSEIQSEHSAVLRGSLCIQIYKPVKLKKIQLSFKGKSRTEWPEGIPPKLFDTYEENSIMNHCWVFFHSEQKVDENSHGAVWYKVLPHYADTAHYPRSMECFYPGEYVYNFELPISCTYPESIQTDMGRVYYFLETLVDRSSTFSGKSTGRIPIELIRSPCSTSVATSEPILVSKSWEDRLHYEVQVGEKCVVMGQVVPVNFKFTLLGEVKFHKLRLFLMERRYYYCRQRSVRRKEKTRQLLLYERSAPKNQCLLSDWKQVRPDVYELSDQVRIPGCHDMAANIVHFDTTYPNIKITHTVRTVLRFSCENSPELMGSAKYLEIYIDSPVRLLSCRCSDGSTMLPAYCPIIPSSEVNFCSIDNRIIAGMNRDLALDSDIIGNSPPSFDSWTAVPYQAPPPKYDDIFQSGSSHDENHDDN
The following text describes a protein:
Function:
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
Subcellular Localization:
Cytoplasm.
Sequence:
MIVGVGIDVLEVERVPEKFAERILGESEKRLFLTRKRRREFIAGRFALKEAFFKALGTGLNGHSFTDVEFLESNGKPVLCVHKDFGFFNYAHVSLSHDRFAVALVVLEKRKGDIIVEGDESFLRKRFEVLERSVEGWEIETSLPPFTLKKLLESSGCRLVRYGNILIGE
The following text describes a protein:
Function:
Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSIEENPFAALLQEGANSDGVPHKLVEEVLLFTLNKASSSAVLCLADVVVETSEEMLSEDLVAHALFERLMLAETSQYAAGNASEMAMERRAMRYLKGAFTRCGLIQAERKIDCSKILALILNNASTCMRQPDLFAPQSFGAQWMEMFEQDEDEHDTSTQEFLIRVTCKVMEEVEPIEALGALKAIFYPVLTELQKNIAKLNLITMKKNTFWILGYFVRDKRAAVLGELLIDYTTPNPRASGSEYMDTLLGSLLCISILPKTQTGKYEFFQELSINQTDEALWALLSHHQQSIFLLVKQLLVLSPETKKKTLQWVGNCLDANVPRGHLWSSINASLEQTAHSTSSDAFMTNLTAVLVRLCAPLCMPSLKVLLVDPTYCAVPNKDRQAKGVSMLRAHAETCLLTSEEGEERLTAEKYNFVTEIFYMTHKCFELSNIPCIERFVRVLRELQNTQMAYGEIVNSDPNSEVAKNLFRMIRDQIQQVLTIKNTLAEPTNDMYLLKFFEASAIWLTEIAMLPREIYEQCLDKRDFSPQVFRNMELLSDTPPFVAPYMQSVPESIIDNISAFLNAARKLNGEQYINIYFSAHDAFFKMIILFMGSSALVKNPHLRAKLAEALEFLLPSRIMGSHRKTFVSHVFDNHPDRLKVVRSLLNVFVSIEMTGQSVQFEQKFNYRRPMYAIMEFLWTKPEHVQCFRDLAVEAEQNMDAIEPPIFLRFINLLINDAIFLLDESLSNLEQIKQLQQAQDNGEWESLPHTEREQHMTNLQHLGMLARFDNIIGRDTINLLKLLTSKIKSIFCHNSMVDRMAAMLNYFLLNLVGPKKERFKVKDKKEFEFDPAQTVIEISHIYINLSSDESFCLAVSQDGRSYSEQLFSYAENILIRIGGGQLIGDMSEFAVKVARMGAQYKEEQELLADAPEEYLDPIISTLMTDPVVLPSSKVTVDRSTIARHLLSDQTDPFNREPLTMDKVKSNEALKQEIESWIQGKREAARSNS
The following text describes a protein:
Function:
Acyl-CoA synthetase required for both the import of long chain fatty acids (LCFAs) (C14-C18) and the activation very long chain fatty acids (VLCFAs) (C20-C26) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. The transport and fatty acyl-CoA synthetase activities are genetically separable and are thus independent activities. Esterifies VLCFAs in the peroxisome matrix. The VLCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Peroxisome membrane.
Sequence:
MSSSWNISQKAALLAGASIPPGYALLRWKYPKLWTDINFYLKAKAYFKTMEHMQISKLFILDIFEEHARVKPNHPCILYENERYTYGEVAGNVNRTARWVIGSDPSLKKGDVVCVLLHNGPAIVWTWLGLQKKGIIASMINYNLKGSALLHCIKASQPKHIIFGSEFIDAILEIQASLRDLKIGLWMINDARIPGLLPPDDAVTMEISTMSGEHFPSAPTTGLGDTGSYIFTSGTTGMPKPAIIPHSKPLGGALFYHQNTGLSADDVYYIPLPIYHSAALLMSVSGSLYFGATMAIAKKFSASHFWDDVRRFRATIFQYIGEICRYLLAQPKKENDGDYPRPLRAIGNGLRLDIWEEFKTRFNIDPIYEFYGATEGNFAFINTDNHLGSVGRYSWLFKRNLANVEIVDYDYETGEPKRGRDGLCIQIPRGSTGLMLLQITERAAFVGYRGPEEMTQKKIVRDVKTKGDAYFNTGDLMKIDVDEYVYFIDRLGDTFRWKGENVSTMEVSHALGLFPAILEANVYGIHVPGHDGKAGMASIVLHKGAILDFSALYQHVISSLPDYARPKFLRLLDEMDLTGTFKHKKTELVKRGFAPDGYGEVYIVEPSRKTYEPINHDHIKMLTAGHSKL
The following text describes a protein:
Function:
Microtubule-associated protein probably involved in the regulation of microtubule organization.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Colocalizes with cortical microtubules and binds directly to microtubules.
Sequence:
MSRISTTSTTPSRVRAANSHYSVISKPRAQDDNGLTGGKPKSSGYDVKNDPAKRRSILLKRAKSAEEEMAVLAPQRARSVNRPAVVEQFGCPRRPISRKSEETVMATAAAEDEKRKRMEELEEKLVVNESLIKDLQLQVLNLKTELEEARNSNVELELNNRKLSQDLVSAEAKISSLSSNDKPAKEHQNSRFKDIQRLIASKLEQPKVKKEVAVESSRLSPPSPSPSRLPPTPPLPKFLVSPASSLGKRDENSSPFAPPTPPPPPPPPPPRPLAKAARAQKSPPVSQLFQLLNKQDNSRNLSQSVNGNKSQVNSAHNSIVGEIQNRSAHLIAIKADIETKGEFINDLIQKVLTTCFSDMEDVMKFVDWLDKELATLADERAVLKHFKWPEKKADTLQEAAVEYRELKKLEKELSSYSDDPNIHYGVALKKMANLLDKSEQRIRRLVRLRGSSMRSYQDFKIPVEWMLDSGMICKIKRASIKLAKTYMNRVANELQSARNLDRESTKEALLLQGVRFAYRTHQFAGGLDPETLCALEEIKQRVPSHLRLARGNMAGNLS
The following text describes a protein:
Function:
May function as sodium-coupled metabolite transporter across the chloroplast envelope.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Plastid, chloroplast envelope.
Sequence:
MAAAAPAAALARHHVLLPPAPPSSSCARNGAAPASVSVCCVLLPRRRRAAPARLVASRRGGGWASSRSRFRAPRAGMDMDLASGAVEVINDLGFDTLTFLGVTVIVVPAFRVVRASPVKYLSPVHPSPPRRIPSLSPCSRVEFQMLLLLLQILGFFCAGVVLNQFGLIRNLTDVKLLSEWGILFLLFEMGLELSLSRLKALARFAFGMGLPQVLLSTLAFTAFELPPNGAIGTKILQFLFNSRPDLVNIRSIDEAIVIGAALSLSSSAFVLQLLAEKGELPTRFGSATLGILLLQDIAVVPLLVILPVLESQNIVEQSVWPILLAESLKALGGLGLLSLGGKYLMRRVFEFVAESRSSEAFVALCLLTVAGTSLITQQLGFSDTLGAFLAGAILAETNFRTQIEADIRPFRGLLLGLFFVTTGTSIDMQLLIREWPNVLSLLGGLIAIKTLIITAIGPRVGLTLQESVRIGLLLSQGGEFGFVVFSLANRLGVLPLELNKLLIIVVVLSMALTPLLNEVGRRVAGIIDENAEEKEKPAEMVNYGATEPIVILGFGEMGQVLANFLSAPLSFGLDQDAEGWPYVAFDLNPAVVKSARKSGFPVLYGDGSRPGVLQSAGITFPKAIMVMYTGKEKTIESVNRLRQAFTAVPIYARAQDLSHLLDLKKAGATDVVLENAETSLQLGSLLLRGLGVMSDDVSFLSKLVRNSMEVQAQEALKDVGDKELDIMMPLQVRVSDLVESDGNGSRMIAQEQSLSLSSRPNLNIIKPPVGSRIPDMKVEKDQPGYDFDGIDSADGVRYCLLEADDETDEASGASKEMIDQSA
The following text describes a protein:
Function:
Binds to mammalian-wide interspersed repeat (MIRs) sequences in euchromatin and promoter regions of genes at the consensus sequence 5'-GCTGTGTG-[N20]-CCTCTCTG-3', consisting of two anchor regions connected by a linker region; the linker region probably does not contribute to the binding specificity. Required for cell homeostasis. May be involved in transcriptional regulation.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MEREASPWGLEPQDVQSSDEMRSPEGYLRGNMSENEEEEISQQEGTGDYEVEEIPFGLEPQSPGFEPQSPEFEPQSPRFEPESPGFESRSPGLVPPSPEFAPRSPESDSQSPEFESQSPRYEPQSPGYEPRSPGYEPRSPGYEPRSPGYESESSRYESQNTELKTQSPEFEAQSSKFQEGAEMLLNPEEKSPLNISVGVHPLDSFTQGFGEQPTGDLPIGPPFEMPTGALLSTPQFEMLQNPLGLTGALRGPGRRGGRARGGQGPRPNICGICGKSFGRGSTLIQHQRIHTGEKPYKCEVCSKAFSQSSDLIKHQRTHTGERPYKCPRCGKAFADSSYLLRHQRTHSGQKPYKCPHCGKAFGDSSYLLRHQRTHSHERPYSCTECGKCYSQNSSLRSHQRVHTGQRPFSCGICGKSFSQRSALIPHARSHAREKPFKCPECGKRFGQSSVLAIHARTHLPGRTYSCPDCGKTFNRSSTLIQHQRSHTGERPYRCAVCGKGFCRSSTLLQHHRVHSGERPYKCDDCGKAFSQSSDLIRHQRTHAAGRR
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MKLLLVLLTIASVALAAVDDVAVNNFKVGILAKDQQPSDENLKTVALFSKLPNELKADASQRLYVSFTVAKKSDNAKVKPHQVFLRFVAQNGEDVVVVVNPDANGNYVYDNVLRTAAKSFRNLSGQFKISLLVGDVTIKNPINWQFANIDAALPVAYEPTPKSQQVHFEPLNEISHIFRQPEKRPSALISDLFTIICLSPLLILVVLWSQVGINFQNAPASPWVPIFHVGLIGIFGIYFMFWVQFDMFVTLKYLAVLGFLTFVAGNRVLRAISESKQKSE
The following text describes a protein:
Function:
Probably acts as an adapter for other myotubularin-like phosphatases (Probable).
Sequence:
MRDPDKVKSGPICDTVAVIVLEESDDENALPDVLHEVQSPHTSDNIPTSSIKKFARPRGWYNQSVSSPSEFFYQILTTERGTRRIAYVLSTWEEDEKTLNFKAVSIVLISQNFHPKAFKEILLEISNDLRTPEFSSSSELIRFLTYELVEEGSTIEIRTKTLHVELGFELIPISPVTGKDVAMLFKMLGFQNVIKIIHALLSDCRIVLASSSLMRLSRCQNAILSLLYPFEYVHSCVTILPDSLAEVLESPTPFLIGVLSEFVTSFGDENIVVYLDNGEVHVPDHAEIYKSDDYYYNSLHQRLRDVMFTTTSQEDLSIPNEERIEVDDFILDKKLRACFIYYFAELLYGYQYYILYTRIKGNFEKKLTTSLTFHVGAFRGFRKLTDMMSSSLLKSVYFQTFILTRALPRRKHDLFDEISCFKELDQLIFKQNSTSSESKKIIEHISCELIQKERYMEKCSARKQEIFTKIHWISGKELAQNNNSIIHTVKPKMRSNVILQAMLPVVNTHAEYHANQFEAYAHRIEALRNCLAAIFEGKVAFASKSLDAVKSSMRFAPLRIELCRLLNQKCSHDKLTDKQFEDIALLMNAALQAECEEDKDGVVRSLMYLSNVYSRKVAQGMQQYMYTAVQEHKVWKNQRFWTSCFYYEVHEMLFSEMLQKDRKITESLWCHTLRPCAMEMINTDDTDQEELVKQENEMIQAQAKHFANILISLQIPLSEEFFEHEDAHRSVLNEKCKWIVNTLDSILGVTGRINGLSLSRIQTYVEAHVESLRDVYVEMSTGEHLKKGNFDPVLAHGEFLISDPIDCYLLTSIEESEMSLNRLENLLPADGSLFLTNYRVIFKGKSVDINATNGTIVQTIPLYSMESFKKLTNKKLIPTQLIEKGVKIEHIISIRSSCASSIIIAFDEDEINNMAIEKFLEVIETNSHNSFAFYNTRKDMKVVENGSHKFGTLNSAIRGFTKKKTDTRRIRSHSSHRGSIQLSFDKMEELDYLKKNAHIRYAVIDYPRIGLNSKIVKLRMSHSNLDYTICPSYPGNFIVPSETNESELAKVAKGFVEHRLPVVVWMNENGALLVRASAFTSIDMVKKLKKVVNYRRNASKLTGSMTGSQQTLHSKASSNEESSSNIVAGAEIKSAEVQMNYIAKLSNSSQRAVSYALPTQYADKFSTFNDGCTLTQNNANGFPTTRIHRKALYVLLEKGHGVKIPIDSNAEAIMVRSVKESELRRSLQRARQICSSEFQVENRTSFLESWNASNWPQCVSRMIELSNSIVALMNLYNSSVAICLEAGRSITTILSSLSQLLSDPYYRTCDGFQVLVEKEWLAFGHYFHKDTETSSPSFICFLDCVYQISQQYPTAFEFSYFYISFLAYHSTAGYFRTFIDDCEEKRLQSDANEFYLPDNLATINVWEFIKLRNRVSAAFYNELYEQIGDIVIPSSSIPQIHMWPFLAETHLKYGSPYDIEPASHEQQLVDPDYEEEEDWSKLNNTDIDERHLNRRVRSPERDPANMDMIRLLQKSYLTELFDASDRKTTTNGESNGKETIHELTPFTVGARPVQCCYCTNILTRWSKAVHCKKCRIHVHEGCVNRNITIGNITHTWDAKPFEDIKMPSGAIQIGTPQAEKMLHSPNNTLTRESMSPPTANTIPPLCTGYLSKRGAKLKLWVPRFFVLYPDSPKVYYYEDFENWKTAEKPSGCIDLVDFKSFNLEQTGRRGLIELHMKNKTHRLLSENINEAIRWKECIEQVIRD
The following text describes a protein:
Function:
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MKCIQSTPFRKWCSLIGFNLITLILLTISVQNIFIDIDPNTCTMTYMVPNYFLVPTNHSMYSLYYYKEGRDLGSANSKLLINDLNQPLKGMPVLFIPGNSGSYKQIRSIGAEAFHHINKGRSSNRFDIENPNKTKKKRSIDYQNELDIFTLNFEEELSAFGGDVMYSETEFVNDCINTILKLYENNNNIHKKPTSVILIGHSMGGVVARMSILLPNHVYGTVTTIITLNSSHRNAPVYSHISTANFYLELNKHWSKSIQPKHFKYNEKGDLTHLPSVYDDIVVVSIAGGHRDTLIRSELTSLDGLVRQDRSFSVVTTSVPDVLIETDHQCILWCNEVVLSLVSGLLLLGNPETKQNTFGPTERLSLLKSVLHSHVPEILGITTFSDQPQFTKENRKNTRYDIDTLSDIAKKKPFESYSMISLIHKPIVSYKSNPRVRITSSASSLTSFYFHFKISDWIGEENYFSLTTSLAQGDFTAILYKDKDFTDAVDVSFNSYSYPPLPPLTNSVIESPSTQLILTHEEMKGHHSLLIAFPKSIRKDRFVAVAQFYNSTSSKVVIPSVSFFDEYRFVLPIGHPIIMNFTLPKYTNKFPIKAVLQTKYLDIDNVNSLRDEDVEASKYSRSLVVNNLKHPEPYTTSISTGISQQQQQQQHQSDPDSNNEGFEDFDIRLAFSMKFIDKEAVIPNNYPIFLPISYHFIPQLMEEGKFVTNCTVTKIKFHQSSKAQLAYRENNNNNNNNNNNNNNNNNNNNKKSFKAINGKLKYLDQKVDSVDNVEYSNNNNNNNNDNSNEEEEEVVVLVVDRFDEQNEQQIQQQRAASDLIKFNQKLLYVQEDPELIDTIPTNSAENTINENGQMEIDINNPHLLMILDPFFSYEIVITYDWIGSIGSLVFSYALSLISCTFALFLWVFSAQLNSFIRNDKFPSLLITLRDQSVQLVPYLIYFPSLVCIVFTIFGLPIPSFYGEFLPDPFIDSFMLERIPPFWSIPFLFIVSICILTILILVTNILFTIGSICSSVCLSILNLINSHPSKNTPIHPRRPNAQNVSFNMDRLDLSNDDGLLNNNNNNNNNNNNINNNNNNNNNNNNNNNNGGNNTNNINSNNNNSNSNNINSTDYINNNNNNNNNNNNNNNNNNNINNSNSFVNNQNLDGTNFNINIENGANNMDSNNLNIERVENTNSFGVNNNNNINNNNNINNNINNNINNNINNNINNNINSNINNSNINNSNINNNNINNSVNNINNIILNNMNNINSGNSDYNNINNNNNNNNNGNSEYNNIYLNNNNINNNNNNILNKDNSNDLLYNNEPIVISNRCTTSTTSSPVTGSFCLGSTVNSRLNGNPQFSSSKWVIIGCIMVIIIHSALGLAAFLLFLMFSSSKQFNGTSNGNSASVNSPSSSISSVSPLLISSISASVKKKSLKIQNAIRKELYYRQSIFLMYIFSAFIMAPNLVIWIKHLSFEWQVFDSFELFILLAITHIFLSTIELNQSNLFILRIALMIASVLVSIYCILFLYRMLYFNLVLSLLYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATVF
The following text describes a protein:
Function:
Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MAIRSLELFEVYYDDSDALAMVCAFASLIPQIILIVYATLIFSRREMETLMLLGGQVACEVANNILKRAIKQDRPRYGPGYGMPSAHAQFVAFLATYLCLWMFFRMRQLYSPVKRVARSVGLVAMTLVVSYSRVHLYYHTPAQVLAGVALGCVLGLAYFLFVSLIRDLGLVDLIVDLPILRAFYVKDTSGDSGSFVKDEFLRWRDKRMKARLIKVE
The following text describes a protein:
Function:
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
Sequence:
MALVSMRQLLDHAAENSYGLPAFNVNNLEQMRAIMEAADQVDAPVIVQASAGARKYAGAPFLRHLILAAVEEFPHIPVVMHQDHGASPDVCQRSIQLGFSSVMMDGSLMEDGKTPSSYEYNVNATRTVVNFSHACGVSVEGEIGVLGNLETGEAGEEDGVGAVGKLSHDQMLTSVEDAVCFVKDTGVDALAIAVGTSHGAYKFTRPPTGDVLRIDRIKEIHQALPNTHIVMHGSSSVPQEWLKVINEYGGNIGETYGVPVEEIVEGIKHGVRKVNIDTDLRLASTGAVRRYLAENPSDFDPRKYLSKTIEAMKQICLDRYLAFGCEGQAGKIKPVSLEKMASRYAKGELNQIVK
The following text describes a protein:
Function:
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Subcellular Localization:
Chromosome, centromere. Nucleus.
Sequence:
MKQEGYPCQFIRKFMFGFPENWKQYVEDFLQDLRNRQKKRKKGGRVQVQKQEAKDQGLGRGKSVEIEERTKVARQKIRSTTFDVDPEKSEKHSELSPVSHNPSKVSELRYSRVGRPLKSPLQFWRGEREICDHEMNVTLHEGGVDHLQSLETTGKMEKKKLSLARKKVKKEVKTNERMNKSHHRERTGALQQEGKEEIQPRQSQSQAEPSLSGVRENEWRSPCILLTPLHSKAVLSQKCMKYNLSRNTMRKISALTMASCNEESKGDKTDLSEAERTLEKSLENLCTNEDWADLIKNPPDSLKKKAKTTSPSRKEPGQKTGNLQRDLSKSSKLKRSKTPVVSRRKSSTRLLSTSSDSEVEQRSQKKAHPVAKPGQRDSNGSVASQRRSPRLAHRESLETAGDKKSTPVVQVKQEKAIFSSDWPVQKSLPRSKYSSGKAELKEVGKAWEPKSSDRFPPLNVEDDWTEEELQRFQSAFVSLPKHRNGFWLDVAMYVGTRSAEECQKKHMEDWQGNGLRPQATKKAVLDQQARNGDANKEPVRITARLGTLKRKQQMRDFLDQLPKDDHDDIFSASPLRARKVKLPVFSVKGDDEVLPLLSTDPATPSSASFPLATTPQCEHISPGMLGSINRNDCDKFVLRMQKDKKGSGGLTWGNVKKQKVGTDFTTPTSRRTGCRRTAVCTPRGADRSGVGKFFTCPTNSHSDEEEEEEDNYFSSSDSEE
The following text describes a protein:
Function:
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex. Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking.
Subcellular Localization:
Cytoplasm, perinuclear region. Lysosome membrane.
Sequence:
MMEVDLGIETVYGSDDTSTGVMSEKVSALASSVYQEFERMIKKYDEDVVKELMPLVVNVLENLDIVTHDNQEQEVELELLRDDNEQLITQYEREKQLRKHAEQKALEMEDVHELQRRDLQNRTEALEMQTRQLELKCKNYSDQITRLEDRESEMKREYQQLHQRHTEMIQTYMEHIERTKMAQSLGQDVAASPKAKLHSILNRPSSPNYYALSNQDVGSPASPKTPQAMSLIEGEDVLGRSPAREPVGLKNTTDLKDEQGGTENGAAQLHGDEKHDGIESQVAEVDVSRDSVHEPGDTAGSEEVVSHDPVSKDDKTATGDVSHNSEHETRPTSTEANEFILLEDNANPVESEIRQTMTDKSLDIQAELCALPPLPLWGSGSEDLRNGGSDRRIQDILNTTPELSQTQPIDVPGATSTPLKANQDSLFQELTSQDSEALGEMDEGADITVSDSFFGMGKEVENLIAENTQLLETKNALNIVKDDLIAKVDELTSEAEMLQNEVSALQTSKQRLKLKVNDLEEELRKARAEVEEMKKGPHDEDDDVPMAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENPELAAKKNKSSIWKFFSNLFSSSSSSSTASKKSYPPVNVRYNAPASQVQPAGNPDRVRSNTFSAMGDKSKAFNFLAEDSNLSEIERKRREKQEQYKRVRAHVRKDDGRMQAYGWSLPAKFKGPSLTEASRNCVVSVPVPVYCRPLLEKEPGMKIWCAAGVNLSGGKTRDGGSIVGASVFYSDSLPDEPEEGKKRGSQTSIDKLDAELKEREKLLPTTENMSSMVWICTSTHATSKVTVIDANNPQEILDTFSVCSSHLLCIASVPGAMEDDYPPEDFVIKGNVVVDADSTETNKSDASSESGIGGITVVGCATGAVPPSQNGKAPGTKDVESPVEIAKEATEIPTPAQEQAPSALEEKMVVKVEGVTPEQEEKEGGEEDGEPEVEEEAGPGEEDEFADPLGATAGGDGPEYTAVPLTQTAPVPRDTLIKDPNSLFKDGMATVPEGAGLPGAEVAKMSSVLPTMWLGAQNGCLYVHSSVAQWRKCLHSIKLKDSVLSIVHVKGRVLVALADGTLAVFHRAADGQWDLTNYHLLDLGKPHHSIRCMVVVYDKVWCGYRNKIHVVQPKTLKIEKTFDAHPRKERQVRQLACVGDGVWVSIWLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRITALLISCNRLWVGTGNGVIISIPLTEISTAPPAIPASNKPTGPPAAASVSRPGGVIRVYSDANSDTVTPGSFIPYCSMAHAQLSFHGHRDAVKFFAAVPEIAVQISYTDLATKQGIAAGLSAATMPSPQPEPSKTAQGSSKNVLVISGGEGYIDFRVGDEDDDEPAPSGPGTGAFGDMSPMAKPSISKGERSHLIVWQIANAE
The following text describes a protein:
Function:
Component of the phosphopantothenoylcysteine decarboxylase (PPCDC) involved in the coenzyme A synthesis.
Miscellaneous:
MISCELLANEOUS: Present with 2940 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MTDEKVNSDQNMNGKQGVNLISSLPTTQVPVSILTNKERRKSIHDESNFERSDSHEDQSKSNSNRRNIYKNDYSTNLRDFSFANLKQNSERNKDGHEIQINTSMPANTNGQQKRFSPSLPSAVSFTVPEVERLPYHRYSISNKPGKQQQQQEQLQQNQQQEEQQKAQLQEQNQRAKQQEEVKQIQEQVQKKQTERQQLIDEKERIANAIFKENTTNDGTDIRKHSVSSGTSNSEDEVDSPSMEKNSIVHMPGDFIYFNPKSNASKPITAKAAPLSANNSTHKNKEVITAPTGPRVPFTEFFQKEDDKKFHILIGATGSVATIKVPLIIDKLFKIYGPEKISIQLIVTKPAEHFLKGLKMSTHVKIWREEDAWVFDAVNKNDTSLSLNLILHHELRKWADIFLIAPLSANTLAKLANGICNNLLTSVMRDWSPLTPVLIAPAMNTFMYINPMTKKHLTSLVQDYPFIQVLKPVEKVLICGDIGMGGMREWTDIVEIVRRRINEIRKARDEETGDKEQEQEEQEGADNEDDDDEDDEEDEEDEEEEEALNETASDESNDEEDEEDEEDVKTEV
The following text describes a protein:
Function:
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MASANDARYGQKDSAEQNFDYMFKVLIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEDSFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVAGQRGRQLSEQLGFEFFEASAKDNINVKQTFERLVDVICERMSENLESADPSMTGNKLGPELSEQPQRSHKDCAC
The following text describes a protein:
Function:
Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs. CPSF6 enhances NUDT21/CPSF5 binding to 5'-UGUA-3' elements localized upstream of pA signals and promotes RNA looping, and hence activates directly the mRNA 3'-processing machinery. Plays a role in mRNA export.
Subcellular Localization:
Cytoplasm. Nucleus speckle. Nucleus, nucleoplasm.
Sequence:
MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTVGDDVGKGAAPNVVYTYTGKRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDRDRERDREREYRHR