lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
Subcellular Localization:
Nucleus.
Domain:
The DBINO region is involved in binding to DNA.
Sequence:
MDRSRRQPSSDSRYATLFNLEPLRNFTIPRHEDEIENYDETRSNQVANYGNGVKKRKRWIEEAGDDDDDHYNQHVTEEHYRSMLEEHVQRLKSSSRESQGNHTSLMRKSNVGSYRGNGQRGRFYDADAISQRRGSYRGSAITPKIAYEPSYLDIGNGVVYKIPPSYDKLVASLNLPSFSDLRVEDFYLRGALDLRSLEEVMASVKRSGVRSRNGMGEPRPQYESLQARVKALSASNSNPNFSLKVSDDAMNSVIPEGAAGSTARTILSEGGVLQVHYVKVLEKGDTYEIVERSLPKKLKVKNDPAVIEKTERDKIRKVWINIVRRDIPKHHRVFTNFYRKQSIDAKRFADGCQREVRYKVARSYKLPRSAPIRTRKISRDMLLFWKRFDKQMAEERKKQEKEAAEALKREQELREAQRQQQRLNFLIKQTELYSHFMQNKTDSKPSESLSIADENLVDEKLREPAAAEPSEVEDPEEAKMKADALKATQEAVSKQKKITDAFDTESMKLRQTSDMDGPPNDFSVSGSGNIDLHNPSTMPATSTVQTPELFKGTLKEYQMKGLQWLVNCYEQGLNGILADEMGLGKTIQAMAFLAHLAEEKNIWGPFLVVAPASVLNNWADEISRFCPDLKTLPYWGGLQERTILRKNINPKRMYRRDAGFHILITSYQLLVTDEKYFRRVKWQYMVLDEAQAIKNSTSIRWKTLLSFNCRNRLLLTGTPIQNNMAELWALLHFIMPMLFDSHEQFNEWFSRGIENHAEHGGTLNEHQLNRLHAILKPFMLRRLKKDVVSELTTKTEVTVHCKLSSRQQAFYQAIKNKISLAELFDSNRGHFNDKKLLNLMNIVIQLRKASSLVKPALLVLLSHTYARLWLMVIYLCLPCQVCNHPELFERNEGSSYLYFGVMSNSLLPPPFGELEDVHYSGGKNPITYKIPKLLQKEMLQSSETFCSSIRRGLSRESFLKHFNIYSPESIFRSIFSSESSVDQAVSGSGAFGFSRLMDLSPSEVGYLALCSAMERLLFSILKWERQFLDEILDSVMEFVDDDLSGGNITRGKTRAVTRMLLMPSKLETSLLKGKRGTRPTCHSFESLVVSHQDRLLSNIKLLHSTYTFIPKARAPPVSVHCSDRNFAYGTTEEMHQPWLKRLLIGFARTSEANGPRKPNNLPHPLIQEIDSELPVVQPALQLTHRVFGSCPPMQSFDPAKLLTDSGKLQTLDILLKRLRAGNHRVLLFAQMTKMLNILEDYMNYRKYKYLRLDGSSTIMDRRDMVRDFQQRSDIFVFLLSTRAGGLGINLTAADTVIFYESDWNHTLDLQAMDRAHRLGQTKDVTVYRLICKETVEEKILHRASQKNTVQQLVMTGGHVQGDDVFGTADVVSLLMDDADAAQLEQKFRELPLQVRDRQKKKQPVKCIRIDAEGDAALEELEDAAERRDKEQEPSQEPEKTKPSNKKRKAAASTPKPRVPPKANEEGDAPLQPQRTKRVKRQTKSVNESLEPVFSASVTAANGEVNPSSSNPDAN
The following text describes a protein:
Function:
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CatSper complex targeting and trafficking into the quadrilinear nanodomains. Targets the preassembled CatSper complexes to elongating flagella, where it links the channel-carrying vesicles and motor proteins.
Subcellular Localization:
Cell projection, cilium, flagellum membrane. Note=Specifically located in the principal piece of sperm tail.
Sequence:
MEPPQETNRPFSTLDNRSGQVQVLSATPLLQRNPYSSPDIMHIKGSEASSVPYALNQGTTALPKNKNQEGTGHRLLNMLRKTLKESDSEELEITQETPNLVPFGDVVGCLGIHIKNCRHFMPKISLQHYANLFIRISINKAVKCTKMCSLLSKNDEKNTVIKFDEVKYFSVQVPRRYDDKRNNILLELIQYDNREKRAFLLGSVQIHLYEVIQKGCFIEEVQVLHGNIFVCRLEVEFMFSYGNFGYGFSHQLKPLQKITEPSMFMNLAPPPERTDPVTKVITPQTVEYPAFLSPDLNVTVGTPAVQSSNQPSVVRLEKLQQQPRERLEKMKKEYRNLNTWIDKANYLESILMPKLEHKDSEETNIDEASENTKSNHPEEELENIVGVDIPLVNEEAETTANELLDNDSEKGLTIPTLNQSDQDNSTADASKNDESTPSPTEVHSLCTISNQETIKAGRIPPLGERQSESMPDRKMKNVFFPLEVKLKDNYPSILKADSSLSEVAFSPKEYNSPSFRPEYIEFKPKFQFQKFNKNGFDPFLRNINKMSVRKRKDQDIYKYRNILGAEVIEHEDQDPPYPAQSKTAGPANTTWAHDPNIFTTKMLETENKLAPDPTINTIKGLDTKNSLKENLPNVSLPSIKGESSRAGNVQANTCHLSKSLNFTPHIEYLKQSMILKSILSENLQDLSDKLFSKPEVSMNSEAREKSSSPLLSIHDKSSSSMEDNVLEKKQDLNNWLSEKDILNSKTTLSQIIKNIPADSFSEGSQIIENIPADSLLEGGQVIKNIPEYSLSEGGQIIKNIPADSFLESGPGQSPEVEEHVSKKHFEADERDFPIKKNSSTKKKHLISEVPNSKSGSSGTVHDYIMRQIFTAPIFSELEIEVKEPSETPMNLENQLPTPWKRSLSSHILFHEENADEIELPQPRSATSQIIQAFPIDTLLESGIIKVIELDKEHHKSSLLGTGITSPKGNLKDSQEYYSEIRSETEPLSEQSIPIIPKDTTSVSRAEFIQEDQNMFPQDSSYYSIANKELYLPRNGQRLCKDKNDLSSTLESLTNSLMDKLSESDEIMLKSFLKNIFNVFFKYNHSERRGQPEKELERLIQPSFTSDTEHLEELQEDFDKADKLDRKPILSPKLRVFLEELSESEVKHLKSELSKQIQHYLVERLSESGHITKEDLPKIYQNLYLMNEKAEQKGPNSFQGKYSETVKEIMSFVNNFNHHFIDKHLEIKLRSFLKEILQNYFLKNISESSLFNETASETIYPNISSLRTKSVSISFHELEQDISKGSFGRRFEINMKYPLSKSLQNYLIALSENELLHLKADLSKHLQSLFIEKLSKSGLMTKKQLEGINQHINLLNSSSIPLKYIKTHLPFRDDCHFVEKHSEKQNKYSRIVQQTTLQTVSEDKLREAELIREKEKKYFPLQNLKGNSSLIKEQKSYYTKEEAKTPSLIKVQPSSNENIQASPLSKSSEILTDILLKKLRKEHVFTQLPQAENSVHKTEIQDPYSWGGKSKITQSKAWCEKTLKMKSLDRKEHVNIYKWTVQEKPEAVLTSYPRIPNARMPREDEYLNRITFPSWQSSTLTHFNTETGEKSKLEDQYCQTLKGNNNNNKKHLVTFAQYKKEIQTLYIKPDEICSEKCAKFPEIQSFQYKVVEDEKNLKPHLFPELFKIEDLKPKVRKERDRVAQPKKSFNKIVRILPTTLPTTRIHLKKSVPRTLLHWTARRTIHDCSDKFEDLHDMTSFTHLKKVKSRSRLLGKSSDDIHNHARHSARPYTAPEVNKQRESYSGKFTSRRMVSSGLVHINDKTSDYEMHKMRPKKIKRGY
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MAAAQLISRGKRRTAAYLKAFLSSDSETSRLQGHQDLHNLLEHFLSPERSIDDPENLEWLQWLVAGGDTPEDFAKIVRRHDNATTCGLVWTANFVAYRCRTCGISPCMSLCADCFQAGNHTGHDFNMFRSQAGGACDCGDTSVMKTSGFCHRHGPGRNMNVPPCPHDVLAVAEAIIPRILLRVVQHFRDHCRPGIDAYEADMDAVHDADSVLTYLHDLTRMGAAMRKVLTHFLTNPQTYKNFTYGSTPSVQKDAFTRTFVQHYSRVSVVLVKASDADTMSNRVVHISVQLFSNEDLTRQMVETHQLLEIVLAALVHMMENIQIQSALHDPDHNFHMVVNCSSSTLKDHRYWPLVSDLINILSHRSTAAMFMSNSSLLSMWAEFVSLFTGMNLNVRELEHHVEFEPNTYYAAFSAELEACASPMWTLVGHCKQKNTDHLCRAVIDSCLTTLQDWFDAICFQETPPPLQVSFHFPLHRHLAVFISQAVRNGAINIDTILGDPDFLVKLMAHPLQIQVALCEIHSGMWVRNGLQIKGQAMTYVQCHFCCSMIDLDIFLLQLCTSRLDPDYCVRTVLERFSVDEFLSLAVVPSALPMNLDQELSMLQGALLLLCTLQSTRTHLGLNERDLLRQEMVSQLCMSDRTHSQLMDLHPKMPERTTGSNQMKDFEAALKEVADFKAPNFEAGGMQQGTYTPKASVWEHEFDPIFILVRAVHRRDFQTAMDRYTTHMKQAGLMEGSESPWPPFRQLQKVLHTYQGIRKILNSKTLHGLLFCILWKALTLSQSLPEPIIYLCIYLLDMAVDPMCNKPAAAAKEDVAACVPDKRWEQWFPSSNILTNLRHEIQYISVPLPQQESMEDLEDIPEENEEDMDTASPTPSRLGFTLAPNVVRGGNVVVTRSREGQTRKSPDASTASSESRDQGSSSCDDTSGSEPMDTTSSSNELKIEVKQSILSMLVKLHDKLSKDTDHYQPPETWEDADLKWSRGSRKHKARDGAHVIGRLLDRIAATCQENLDKLKQLCCKTTPKKFHRRASDGGDREERRRKARDKQAKLLAEFAAKQRTFLESTSMDEDDSGEGASAESPEKEVAQEEEVYDCVICGQTDPSTPDRPIGRVVLLLASSVLGHRTSKDEPPRLPCSDGATLDMLNCGNTYDLRQTVMQDNFQMSSCLQSVSVGWFGGVYVQSCGHFLHSDCHKSYIRSLRSPDYQHTTQNIDVDKGEFTCPLCRQLANSVLPCQPHQHPLQKLAMEKKRYGSHKKTTPAKEQIKSEQEKAALAQKAAEASKPEEKQKADQAQASTSEELPSQEDKPEDKKDEESGRVSPEFPRSIPTPWRQQAHVMKENQTLDPKPEFQRMIKDLGEVLRKATNADCEDDSILRQGVEAIMEDITKATYPKYKVFPKSSVDESLNVFVHSVARTNLELELVQIGNTIVNHSSSSRKFGFVDLLHVLRFHFNATGMDSLWSKLTTLYSDEEERTCSVRLHPELLMLVEKRETPMVLRDASALLIQLTLSLPWPISKAHFTCIVRVLFTLLYTQSLVDISCRFSEEERKAWREAGTDKAASTECMMTESMLSCLISHLVHTPLYHDTDTDLQRVDISQSVWSPHSVEHHIQKYCIHSLRIAALLRRHLFKEDLPDCQNPEQEFQTLVKFLDLQHVPLPTRGDASAARERPFTSASCLHWAVPATQMISHWCQDFTSFVNRKQGPAKLQPRGGYKSLLLKNFAWQLPCLLRPPSSYDSIFQYHRQRQCTMCCSVPKEPALCMVCGELLCMKGGCCRQQSVMECVQHSISCGAGTGVFLVVNSSTIIVVRGPRACLWGSLYLDSHGEEDRDLRRGRPLYLSEDRFRVLTQQWISHSFDHMCKRWLWHHNRL
The following text describes a protein:
Function:
Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MSSLDEVAESRKQRLAELRKIKQLENKTRDSQEVQKNVIEHRNYDPEVQAPKMGFVEPPNMIESVEALSKEIEEKTKRKIEEQSSVPVEELDLVTLRPKKPTWDLERDLKERMRSLETQNQNAIAFYIQQLISERAHSTEKA
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere. Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MEGDRAGGPAAADLRRDMAACERRIAQGRDRTAAAASAFRGAVLSARSLAEHSVAHREKLNALKDQLRGLEAALAEALSTQLKKESECKHTSESISNATATNEQLRGLVSEQRARRDEYANVIAHQLEAVEALEANVDATGKKNLDEAITWYDKFLGFRVVAGEGVKFVFNKVDMQSPDDEYSFCIKVNKDEYSLIQCIPLLKDTEELVKDLNRTNDLFKFVRTMRARFQAAGIKGVHPATSLCQDTSSTPISSPPAVSVDTTSEGSTNQSHSRSRSKNQDTRAKRGAPPRSTASPLTSGSATRRSPRFAAADAGNKH
The following text describes a protein:
Function:
Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MLGDHSGLPADRALLSQPPKTGLRCKMVLQAVGKVLRKSKAKPNGKKPAAEEKKMYLEPEYTKSRITDFEFKELVVLPREIDLNEWLASNTTTFFHHVNLQYSTISEFCTGEACQTMAVCNTQYYWHDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVKKICKYLFHVLAHIYSSHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAVMDDLTEVLCSSGGRGGGSGDGAGSGGMGAQNHVKER
The following text describes a protein:
Function:
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.
Subcellular Localization:
Secreted.
Sequence:
MKVSAAALCVILTTAALCVPASASPYASDTTPCCFAYISRALPRTHIKEYFYTSSKCSNLAVVFVTRKNRQVCANPEKKWVREYINSLEMS
The following text describes a protein:
Function:
Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N-myristoylethanolamine > N-stearoylethanolamine > N-oleoylethanolamine > N-linoleoylethanolamine > N-arachidonoylethanolamine.
Subcellular Localization:
Lysosome. Membrane; Peripheral membrane protein.
Sequence:
MQGTGHPVRPVLELLLLLLLLAGVGGSTTASTPGPPLFNVSLDVAPERWLPVLRHYDVELVRAAVAQVIGDRVPKWVLALIEKGALKLERLLPPPFTAEIRGMCDFLNLSLADGLLVNLAYEYSAFCTSIVAQDSRGHVYHGRNLDYPYGSILRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDRGWWWENLVAALFLRHSPISWLLRTTLSEAESFEAAVYRLAKTPLIADVYYIVGGTNPREGVVITRNRDGPADIWPLDPLKGVWFLVETNYDHWKPAPEEDDRRTPAIKALNATGQAKLSLETLFQVLSVVPVYNNYTIYTTVMSAASPDKYMTRIRNPS
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MELLRRKRKGLEVLPLCSKSFASSAIIWSHLSLGDYSRQKKKCKEDEGKEVGSPRTVVKGIVTAPHCRSSCFNPPCRGLKRKIGCIDVATQLGRKKKIEQQYDLGATIGKGKFGSVVLCTRKVTGEDFACKILRKGEDLVHREVEIMQHLSGHPGIVTLKAVYEDSESFYLVMELCSGGRLLDQMAREGQYSEHHAANVLRELISVIKYCHDVGVVHRDIKPENILLTTSGQMKLADFGLAMRISNGQSLTGLVGSPAYVAPEVLLGDYSEKVDIWSAGVLLHALLIGILPFQGDSVDAVFEAIKKVNLDFESGLWESVSKPARDLIAGMLNRDISSRPSADEILRHPWILFYTEPTLKVLTVKPKFGNHVRLTFEKLTIKDELESERFDATTSSILSDETSLILSSGGSKRLSEQDCGLVDVLAVAISRVRISEPKRSRLCGPTSPIQRECSSNIKVNNLCTAF
The following text describes a protein:
Function:
Skin-specific kinase that plays a key role in glycerol metabolism, catalyzing its phosphorylation to produce sn-glycerol 3-phosphate. Involved in skin-specific regulation of sterol regulatory element-binding protein (SREBP) processing and lipid biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MSDDAKNSSQDDANILGNSSATEQPPNGPREQVPDSPKHQAGQNGPRDQYVVAVDVGTTTLRCHVYDKLANVKGSSSKKVHLLHPKPGWVEMDPEVLWTDFVDVVNEAIRAAGLTADQVAGMGISTQRSTFTMWDRETGKLYHNFLTWQDLRGAELVDLWNNSFTMKALHGGGGLLYYMSRSKRFLAANLLKFLPQQITMKVMWMLQNNLTLRRRAFNGLVSFGTIDTYLLWKLTGGQVYATDYSCASSTGLYDPYIKQWNKFFTNLLSIPISIFPPVEDTSKIHGVCETKLFGAPIPIASLVADQQAAMFGECCFDPGDVKCTMGTGTFMDINVGSNPHTSMAGLYPLIGWKIGDEIVYLAEGNASDTGNAIDWARSIGLFDDYTETVEIVESVEDSNGVHFVPAFNGLQAPVNDPRACSLFLGLSATTTKAHMLRALLESLVFRNKQLYETMLNETKIPITYIRADGGVSNNSFVMQLTADLLNRTITRPKHVDMSSLGAAFLAGLAVGFWKDKEEFRRLKDGMTNHVQIGMWTSKEELKDLQSSEKVFHPRPVSEGVWEKYRPVVEQWEKAVKRSLYWYPAKN
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Cytoplasm. Note=Septum.
Sequence:
MVGLISTSETLPKQESKSSSAPVSNFLSPNNLTEQTCSPLRAHSTFKEPVFLLSQRQYSHNSKILTELINSVKRPNKPDQNEEKSAVGIEEKSFKDEHLAQKKGLHHFADLKEIFLNKNLSTLDGLQDASLHDNIQSGKLDNPVISQNRRIVLEKLANPNSSKEYETIPTVENRHPLNKLSKTKTLAYEETINQLDETPGGTNYPMNKKKTLSSETNKYEYPQQSKFHECSQFASPRSSIVNGPRTLGKNSKRADDTARMASRMKPSNFNNNIQSSSYGHASQSTKLTSQRDNDHQKDLNFSPYKSIPLNNRPYSPMSEIVGFSGSTTPLDTYGNRPSGKKFNKNSKFRPPGSTISSYSSASTLRRLPRAPGSKVHAERQNSTFNSGISLRALRKEMGNTAPVSSNQLLKDADLVMENLSTRNTEKVLREVNILKRLRESCVAITAKSYDTLDERKIRSLTTFEYLEIKNFQKIYFTGSENCQKLSKQIPLDECNEALFDDDNGDYKAIQGDHLLYRYEIIDTVGKGSFGQVLKCIDHKRGQVVAIKVIKNRQKFHGQTLVEVGILKRLCEADPADKNNVIRYLSHFDFRGHLCIVTELLGSNLFDVIRENNYKGLPLIVVKSFALQGLQALRLLQGQNIIHCDLKPENLLLSHPLKARIKLIDFGSSCFYNEKVYTYLQSRFYRAPEIILGLEYGKEIDIWSFGCILAELFTGVPLFPGGNETEQLGYIMEVLGPPPMALIRNSTRSKAYFDSEGKPHPITDSHNRLLVPSTRTFSQLLNTKQASFLDFLSKCLKWDPKDRITVDSALQHEFILGKTSQKPMVSKGSHPLPDLPV
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (By similarity). Binds GTP with specificity. Plays a role in the root morphogenesis by regulation of the cell proliferation. Acts as a positive regulator in resistance to pathogen that triggers the salicylic acid (SA) pathway. Promotes the DNA binding activity of RTV1 specifically to promoter regions of FT and SOC1 in vivo leading to the activation of floral integrator genes.
Miscellaneous:
MISCELLANEOUS: Dark-grown xlg1-1 xlg2-1 xlg3-1 triple mutant plants showed markedly increased primary root length compared with wild-type plants. Dark-grown roots of the xlg triple mutants also showed altered sensitivity to sugars, abscisic acid (ABA) hyposensitivity and ethylene hypersensitivity, whereas seed germination in xlg triple mutants was hypersensitive to osmotic stress and ABA.
Subcellular Localization:
Nucleus.
Domain:
The helical domain (492-627) is required for self-activation.
Sequence:
MAAVIRKLLPFPSPNPKRDNRESDDDDETSSGYRIEYSFASEYKGPLIANVPRALPVEVDQIPTALPVSFSSLRSGISYPVAPLVMTKDTKRPPDSGIEKKNGFVDSAAGSSVVLIGRDVVSGSSSSSSSKRLDVPEEVKSPADFRLSPSSPLSASAREEDHLDDDRVSDVGPRAVRFVEPFQSSECDESSYVSDGESIAATHRAERKGKRGSCYRCQLGNRFTEKEVCIVCDAKYCFNCVRRAMGAMPEGRKCQACIGYRIDESKRASLGKCSRMLKRHLTDSELRQVMNAEITCKANQLPSRLIIVNDKPLSEDELYTLQTCPNPPKKLKPGHYWYDKVAGYWGKIGEKPSQIISPNNSIGGYISEKVSNGDTEIYINGREITKPELTMLKWAGVQCEGKPHFWVDSDGSYREEGQKHPIGNIWSKKRAKIACAVFSLPVPPASSAVEPYDVPLYEQKMLNKLLLIGSEKGGATTIYKQARSLYNVSFSLEDRERIKFIIQTNLYTYLAMVLEAHERFEKEMSNDQSSGNVGDETSAKPGNSINPRLKHFSDWVLKEKEDGNLKIFPPSSRENAQTVADLWRVPAIQATYKRLRDTLPRNAVYFLERILEISRSEYDPSDMDILQAEGLSSMEGLSCVDFSFPSTSQEESLESDYQHDTDMKYQLIRLNPRSLGENWKLLEMFEDADLVIFCVSLTDYAENIEDGEGNIVNKMLATKQLFENMVTHPSLANKRFLLVLTKFDLLEEKIEEVPLRTCEWFEDFNPLISQNQTSRHNPPMAQRAFHYIGYKFKRLYDSILEPVNMRGRSFKPKLFVCQVSLESDTVDNALRYAREILKWHVEETSMFQEMSTTSIEASSSS
The following text describes a protein:
Function:
Probable transcription factor that can both act as an activator or a repressor depending on the context (By similarity). Involved in posterior spiracle development. Acts downstream of ems and cut in posterior spiracle development.
Subcellular Localization:
Nucleus.
Sequence:
MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLIGAPTAAGQEDHPTEGKINGGADGEDLPKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGATAGGGATGAASKFDKLTGEGIKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRMDFPKRSRSNHVGGTTTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQPQTQAVKTPVQEGEGFQLSCEYCTMKFGNIAGLFQHMRSTHMDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPERESRPAEDDLPTDLSNNKRRPLTPNPQAQTPLAPPSAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGMSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGATSSAPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKEANSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGASGGAGSGGGGAQSGGAPPSANKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPSGNEGVGNSQPPAPQATAPPPPPNASTATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPDATEGPAKLCDKCCRKHNLNGKRGKHSEPATSLPAPPSAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMGEHGAHSRPYDCNLCPEKFFFRAELEHHQRGHELRPQARPPAAKVEVPSIRNTSPGQSPVRSPTIVKQELYETDTVESAGVEDEPENHPDEEEYIEVEQMPHETRPSGIGSQLERSTSSA
The following text describes a protein:
Function:
Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
Sequence:
MKKVELTEQALMILEKRYLKKDENGNVIETPEEMFERVAETIAKVDLIYDPNADVEAVKDIFYEMMSSLEFLPNSPTLMNAGRPLGQLSACFVIPIEDSLVSIFDGLKYAALIHQSGGGTGFSFSKIRPKGDIVRSTGGIASGPVSFMKVYDAATDTIKQGGVRRGANMGILRVDHPDIWEFVTCKDQEGVLSNFNISVAVTDGFMEAVLNDEEFSLINPRNKEVVKRIRAKELFDLIVEQAWKNGEPGVIFIDEINRKNPTPEVGEIESTNPCGEQPLLPFESCNLGSINLGRMLKKVGDKYEINWDKLRTTVHNAVHFLDNVIDANFYPLKPIEEMTKANRKIGLGVMGFYDLLIRLEVPYNTKEARDIAENIMSFIQKEAREASQELAKERGVFPNWDKSIYRDMGLRLRNATLTTIAPTGSISIIANCSSGIEPIFALAFKRKISLGEWNEVYPLFKEALIKENLYSEELIEKVIQKGTIQNITEIPEKLKRLFVTALDISPEDHVLMQASFQKYVDNAVSKTVNLREDATLEDIRKIYLMAYELKLKGITVYRDKSRASQVLAVEKEKKETKERDAHKLIPRPRPTITKGATIKMRTGCGNLYITINEDEFGICEVFSTLGKAGGCAASQTEAISRLISLALRSGVDVNAIIKQLKGIRCPNPARTEDGDLILSCSDAIGKALEKYLNLKEGKNNTLNDFIVRSEEKTEKSENYSGMPCPECGSPLQVAEGCLTCRVCGYSKCY
The following text describes a protein:
Function:
Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis (By similarity).
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus.
Sequence:
MATKIDKEACRTAYNLVRDDSSAVIWVTFKYDGSTIVPGEQGAEYQDFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIKNELKKAGGANYDAQTE
The following text describes a protein:
Function:
Probable RNA-binding protein that plays a role in meiosis and vegetative growth.
Sequence:
MQHSSQHFAFGPSKITSMSFSKVVGSGARDMLTGSDAYNDASSDTTLFSSSLPVLPHEKLISNNAENDFQSLEGNDLLEELEDHAIGNLLPEEDELLAGVIDGFDLNTFPSRADELEDYDLFGSGGGMELESDMDTLNVSMSKVGLTDGVVGNGVAHYTLANGVATVAGEHPYGEHPSRTLFVRNINSNVEDSELRTLFEQYGDIRTLYTACKHRGFVMISYYDIRAARTAMRALQNKPLRRRKLDIHYSIPKDNPSDKDINQGTLVVFNLDPSVSCEDLLQIFGAYGEVKEIRETPHKRHHKFIEYYDVRAAEAALRSLNRSDIAGKRIKLEPSRPGGARRNLMLQLSQEFEQDDTRSFRLQVGPSMANSPPGVWPQFGSPIEHSPLQSLSKSPVMGSMSPTLPGLASILHPQPARIAPIGKDHTRSNRTHLEQNLFNGNSNTFQHSHSLPESKLSQFNESISLSSFNGGGSTSTGGGSGIETLSGPQFLWGSPNIYPEQTQPQQQPKGPSPNHGFAIATRTRSPSISMGHPFATSKGLTTHGLPITARHGSLLGSTQVQHHHHHHQQHHVGSAPSGIPFEGHFGLGRYHESPETLFMSPPAFGGGVGVGVGLGHIDRGGFLGSHGCVENGSPSFSPRLSPMFLGNGHYPGLGPTIAETMSDRGRNRQVDQNGSQTDSKKQFQLDLDKITSGEDTRTTLMIKNIPNKYTSKMLLAAIDENHSGTYDFLYLPIDFKAFNGKKWEKFNSEKVASLAYARIQGKTALVTHFQNSSLMNEDKRCRPILFHSEGSEVTDQEPLSSSSLNIQMHRSNGSDSGDSSGSPPKDGAAEQS
The following text describes a protein:
Function:
Regulatory protein that activates transcription of mdaB, encoding a NADPH:quinone oxidoreductase, and represses its own transcription. Under the same experimental conditions, no regulation of transcription of pilus and capsule genes is detected.
Domain:
Each subunit contains an N-terminal DNA-binding domain, connected via a long linker helix to a C-terminal regulatory domain.
Sequence:
MKTNSEELTVFVQVVESGSFSRAAEQLAMANSAVSRIVKRLEEKLGVNLLNRTTRQLSLTEEGAQYFRRAQRILQEMAAAETEMLAVHEIPQGVLSVDSAMPMVLHLLAPLAAKFNERYPHIRLSLVSSEGYINLIERKVDIALRAGELDDSGLRARHLFDSRFRVIASPEYLAKHGTPQSTEELAGHQCLGFTEPGSLNTWAVLDAQGNPYKISPHFTASSGEILRSLCLSGCGIVCLSDFLVDNDIAEGKLIPLLAEQTSDKTHPFNAVYYSDKAVNLRLRVFLDFLVEELGNNLCG
The following text describes a protein:
Function:
Plays an important role in controlling cell cycle progression and DNA damage-induced G2 arrest. Involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Also involved in p53-independent DNA damage-induced G2 arrest mediated by CREB3L1 in astrocytes and osteoblasts. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex. Inhibits DNA synthesis by DNA polymerase delta by competing with POLD3 for PCNA binding. Negatively regulates the CDK4- and CDK6-driven phosphorylation of RB1 in keratinocytes, thereby resulting in the release of E2F1 and subsequent transcription of E2F1-driven G1/S phase promoting genes.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSNPGDVRPVPHRSKVCRCLFGPVDSEQLRRDCDALMAGCLQEARERWNFDFVTETPLEGNFVWERVRSLGLPKVYLSPGSRSRDDLGGDKRPSTSSALLQGPAPEDHVALSLSCTLVSERPEDSPGGPGTSQGRKRRQTSLTDFYHSKRRLVFCKRKP
The following text describes a protein:
Function:
Demethylates proteins that have been reversibly carboxymethylated.
Sequence:
MDPRRNGSDAPGLGAGGGRPPAMPSAQETYYSSAAHRVLTPLSWEGYFDSKHTTSKGFTYYRKGTTGPNVLLLHGGGHSALSYACFAKLLSELSDCQIVAYDARGHGATQVTEGSPEDLRLDRQVQDCRHIAEEALDSAAKTIIIGHSMGGGVAAHAAHGGFLPNLAAAVVIDVVEGTALDALSGMKSFLRSRPASFASEEEAIKWSIRSGQLRNTESARISMPAQVRLAEEGEAEELEEQAIPNTIVEEEEEEEENEPGVGSDSSRRSGRQQEGVLPPEDVMFAKPQRQAAPAEKQPGKYVWRVDLVKSAPYWQEWFEGLSSTFLRIPALTMLMLAGVDRLDKELTIGQMQGKFQLQLMANCGHSVHEDAPGQAAAAIADFLARFKLATRKHPA
The following text describes a protein:
Function:
Component of the NC2 complex which represses RNA polymerase II transcription through binding to SPT15/TBP and thereby inhibiting the assembly of the preinitiation complex. The NC2 complex may also mediate transcriptional activation from TATA-driven promoters through association with SPT15/TBP.
Miscellaneous:
MISCELLANEOUS: Present with 2950 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MAGDSDNVSLPKATVQKMISEILDQDLMFTKDAREIIINSGIEFIMILSSMASEMADNEAKKTIAPEHVIKALEELEYNEFIPFLEEILLNFKGSQKVKETRDSKFKKSGLSEEELLRQQEELFRQSRSRLHHNSVSDPVKSEDSS
The following text describes a protein:
Function:
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
Subcellular Localization:
Cytoplasm.
Sequence:
MQEILIPLKEKNYKVFLGELPEIKLKQKALIISDSIVAGLHLPYLLERLKALEVRVCVIESGEKYKNFHSLERILNNAFEMQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTTLLAQVDASVGGKTGINTPYGKNLIGSFHQPKAVYMDLAFLKTLEKREFQAGVAEIIKMAVCFDKNLVERLETKDLKDCLEEVIFQSVNIKAQVVVQDEKEQNIRAGLNYGHTFGHAIEKETDYERFLHGEAIAIGMRMANDLALSLGMLTLKEYERIENLLKKFDLIFHYKILDLQKFYERLFLDKKSENKTIKFILPKGVGAFEVASHIPKETIIKVLEKWH
The following text describes a protein:
Function:
RNA-binding protein involved in post-transcriptional regulation through transcript degradation.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm, P-body. Note=Localizes to P-bodies at high temperature.
Sequence:
MASHTLRPHRSPSPSPEPPVNLANPAKLTRQSLGPPTSGNSKGFGSLGLGPGLASPSSPSQPRHVSSSVAMGMGNRDSLSPRPSGVGSGRAVSATTGPRPSSEFIPTREAKTPEAEQIDQWFKHLANWEATLEEMAAASTDQNFTEELGAIEQWFRVLSEAERTAALYSLLQYSTPVQIRFFISVLHHMSQSDPMSALLSPSLSGSNAFQTQVESKLSNMNLKSPSAGGGAGFAGSSGNGHYLAPDDAAAKAAKARQNRISAPGTLQPHDRWQGQLDQVVERGTSPGLESNMSGRSRSKSPTPEPRPKSTDFSGKPRESLRRESAAFPRSPRVSAGSPGIGLGIGHESPMASPFGNNASWASMVNTPLVQNFNDGKLVAPASVADLSQALNMATLQLNNPGYLPLDDARKYRRPTGGLASGQTSRNVSGQYNDDGEIVNPHTTQPGTPSGLLPNQFGGGRSPLVDQFGLGGLGIGADSTTLANLGLNYNLAGLGGVNPGLNGLTAAQAQAAQMLAMQQQLQNSQYSPFNASAPSLQPGLNPSRRGAGRGQSSHLNQHYNQHQQQHQPGRRSPNPLKSHSPAPGQQTGGGGAGGGAGVAGPEDVDVKVLEDVPNWLRVLRLHKYTPNFEKSNWNDMVLMTDQDLQDNGISAQGARTKFLKVFYNVRTKMDIAHPPGQEEYAPGPKESK
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, flagellum basal body.
Sequence:
MAPKSATKKKAKKKPLTEEEKKAKADFDALKAVEMRKKAIRDRKSAFKNAMIDEEKLSVKSMLEIHKKWRSILRIAKIKEQRDDIDWLTKNHVRQMELKDHIIGLYREQLYESEAQRRSAQIKHLSMLDASIDIHYLRTAKMEEEFQEQVKNLEDSFMTERKLMTTNFSNEKKELKDVILAMKVQAEESIYDRRQNKDIEEFNMLKITLELGVEEIERRIERTHKSYLANTEATTISFKNLVAKDIVKSHLIERRMRTLINLHENISYWRVRMVIQGKEFNKVNQKMKDEKECLLNHYTALKRLLGRIKHHERDNLKEVSRNVSDAKNHLMDKLVVAQRVLHLAKRANKLETEHEKIFPFEPLHCFNIPTVPGLVLDRELAEDETTKKSEAKMLGHSVALLVPTQFQVEPKPPEVINGKNPFHWGTYALDENGNEVEESHYMANFNKRFNKVKLDLLTIQTERNRLSEENSKLINGLQKYMDSQIMPK
The following text describes a protein:
Function:
Heavy-metal-binding protein.
Sequence:
MAMRELSQLNRDSDGDEEVWVKHYSSNHQILLVGEGDFSFSHSLATLFGSASNICASSLDSYDVVVRKYKKARSNLKTLKRLGALLLHGVDATTLHFHPDLRYRRFDRVIFNFPHAGFHGRESDSSLIRKHRELVFGFFNGASRLLRANGEVHVSHKNKAPFSEWNLEELASRCFLVLIQRVAFEKNNYPGYENKRGDGRRCDQPFLLGECSTFKFRFSRVAKELYAEKVRSREVKERESMYPEAILNKQPVSFDHRYRLQTEFEAIAGTITLGKSKILWLSQEKGHLHWIFVTTKNVDVYSSKIPVFLICTLESRQRDIACFVKTFQFKLVKNHYPNTLTAGVEFLVKFITGKYEECQQVTYLRKNFSGYGDGNKQRIVLKMDMSDEKSMKKAMKIASAKPGVRSVSIQGQNDQLVLLGEGIDLAELTRELKKKVCMTTIITVQAAPPQQPPQPHPMGQYNQMPPARRCTCEIPNSGFCGFCRSMSQPNYQVVPSPYYPPMLYCRDETDGCRIL