lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the perception of CLV3 and CLV3-like (CLE) peptides, that act as extracellular signals regulating meristems maintenance. Required for the sensing of the root CLE peptides (e.g. CLE8, CLE9/CLE10, CLE11, CLE13, CLE14, CLE16, CLE17, CLE18, CLE20, CLE21, CLE25, CLE26, CLE40, CLE41/CLE44 and CLE45), which also involves CRN and leads to root growth regulation, mostly in the phloem and protophloem. Involved in controlling the stem cell population size in shoot and root apical meristems, and during organ development. Promotes the formation of CLV1 multimers. In complex with CRN, perceives secreted CLV3-like effector proteins from plant-parasitic cyst nematodes as ligand mimics of the plant CLE signaling pathway. This recognition is required for proper feeding structure (syncytium) development and ultimately successful nematode infection. CLE14 perception by CLV2/CRN complex triggers root meristem differentiation.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Requires CRN for export from the endoplasmic reticulum and localization to the plasma membrane.
Sequence:
MIKIADFTLFFFIFVFSPSLPLAQSQLPDLDPQDKASLLIFRVSIHDLNRSLSTWYGSSCSNWTGLACQNPTGKVLSLTLSGLNLSSQIHPSLCKLSSLQSLDLSHNNFSGNIPSCFGSLRNLRTLNLSRNRFVGSIPATFVSLKELREVVLSENRDLGGVVPHWFGNFSMNLERVDFSFCSFVGELPESLLYLKSLKYLNLESNNMTGTLRDFQQPLVVLNLASNQFSGTLPCFYASRPSLSILNIAENSLVGGLPSCLGSLKELSHLNLSFNGFNYEISPRLMFSEKLVMLDLSHNGFSGRLPSRISETTEKLGLVLLDLSHNSFSGDIPLRITELKSLQALRLSHNLLTGDIPARIGNLTYLQVIDLSHNALTGSIPLNIVGCFQLLALMISNNNLSGEIQPELDALDSLKILDISNNHISGEIPLTLAGLKSLEIVDISSNNLSGNLNEAITKWSNLKYLSLARNKFSGTLPSWLFKFDKIQMIDYSSNRFSWFIPDDNLNSTRFKDFQTGGGEGFAEPPGKVEIKISAAVVAKDELSFSYNLLSMVGIDLSDNLLHGEIPEALFRQKNIEYLNLSYNFLEGQLPRLEKLPRLKALDLSHNSLSGQVIGNISAPPGLTLLNLSHNCFSGIITEKEGLGKFPGALAGNPELCVETPGSKCDPANIDASQEEIYQNELVEGPISIWIFCLSAFISFDFGVLGIFCSARARSYILQTKA
The following text describes a protein:
Function:
Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
Subcellular Localization:
Nucleus.
Sequence:
MVSIESIREQFDELGIEPSDEVVNKCIEICINNDITDPVEFVEQWMAYSVSKLSGAEPTVAYLNEMEAHEYTSKARKLTKVSSIAATSGSIGTSPRMDSKVSKITTYRNVDSVEQDVLEMYGCITPKAKKTVSRLQHNVNTPNGVRGGGSGGSPFTTVTYSPLSASSKKNDPDAPSKAGQIVYTYGSAKLLKQFNWLPTTTDGGKEPIPIDDDLSLGDRNRRTGAGRGKGIGFTIKSAQFANDGCKYMYDSSYDRVMILGDRIYECGNAICKRVALEAVKPKSHEQPAKNNDEPDVKSNSASALDTPLPVKEEPASEETDVDIEREEDRLSSWFEGIKVHHVDYPSSELIRVLGRIVVESSSTTTNSSSGTTSDKQVASNRNPTTTSKLSIVDFDEHTLRYTRLDLSKVQVPSWWSLFPGQTVLLEGINPRGTLFSVKQIHCERTLALPRVPTSLDKTLTCVIASAPFTDRDDLLYEKLSSLLVYCSNNPPDVLILTGPFADANCKLYAEVAETFDEYFEKIISTIMSSIGIYTEVFVVSHHDDLVSSFVYPTPPYKVASFYKNLHFLPDPCVFNLEGVEIGITTVDVIKHLIESECTVANVTIGSAPPLGGDKIKRAYGHLFHQASFYPLNPPPEDVPLDVDMLNEFGRLSRVPNIMICPSALNRYVREINGCVCINPGFVDGHSADGSYARLIIQAPEIDEQQQRESQSDSIQPSPASYIACQIVKT
The following text describes a protein:
Function:
May be involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MHGHGGYDSDFSDDERCGESSKRKKRTVEDDLLLQKPFQKEKHGKVAHKQVAAELLDREEARNRRFHLIAMDAYQRHTKFVNDYILYYGGKKEDFKRLGENDKTDLDVIRENHRFLWNEEDEMDMTWEKRLAKKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKSWEVNFGYIEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEEFDEYFQDLFL
The following text describes a protein:
Function:
Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MMNEVMQGDTFRCIECGFSARELYHDYGNGIIKISHCEKCKQVVDKYVEFDPVIVLLDALLFKPQAYRHVLFNKVITFHWRVCIVCLLCDAYMKWAHKSAAPTEGESKPFLTYALQWDFYAMFMIAGLELLAFIAGVVGICFLHSALSNSREHWKARSSRLVKALLLSSAGKLLVIPVVIWGETHIYTTLLLTRLFMAVASTQAITVILDCPHITSISLIGCGFITEALVSLLTPSIESILFVS
The following text describes a protein:
Function:
During FMRFamide-like peptide (FaRPs or FLP) and neuropeptide-like protein (NLP) precursor processing, catalyzes the removal of Arg or Lys residues from the C-terminus following the initial endoprotease cleavage. By processing neuropeptides, modulates basal acetylcholine release at the ventral cord neuromuscular junctions. Involved in egg-laying, defecation and locomotion. By processing FLP neuropeptides, regulates the turning step of male mating behavior. Involved in reducing pharyngeal pumping in response to high CO(2) levels.
Subcellular Localization:
Cell projection, axon. Perikaryon. Cytoplasmic vesicle, secretory vesicle lumen. Note=Predominantly localizes to axons in the nerve ring.
Sequence:
MLHAMRPVLLVAALLAVTAHAFLGFGSGSTHKDDAEWGHYHNQAQLEAKLGEINEKCPEITTLYEIGQSVEGRPLVVIQFSTTPGEHIPTKPEVKLIGNMHGNEPIGRELLLRFAETLCNGAINNDKEIVQLLNSTSIHILPSMNPDGFELALGTEPAQRQWLTGRSNINGVDLNRDFPDLDSIFYELQKIGVPKFDHLLSLFEDNVDRQPETIAVGQWTLSLPFVLSANFHEGDLVANYPFDAAIDENSQKTAYSASPDDGTFRWLAKSYADNHAHMSKNDHAPCDGTSQDAFARQGGITNGAKWYSVAGGMQDFNYLATNAMEITLELSCEKMPEGSQLPRFWEDNQKSIFEYVWKSHSGVKGMVVDAMTGEPIKRAVVWIRNGTETVPVKHPVTTWSEGDFYRVLPAGKYEIIVAAEGYDIAAKNVTVENKVRDSALVVNFALSPAADEPSENEQEQIAELVNEIARRR
The following text describes a protein:
Function:
Has potent antibacterial activity against E.coli (ATCC 25922).
Subcellular Localization:
Secreted.
Sequence:
MKIHYLLFAFILVMLSPLAAFSQLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK
The following text describes a protein:
Function:
Stimulates specifically the GTPase activity of YPT6.
Miscellaneous:
MISCELLANEOUS: Present with 2990 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MKDVLQWAIDHYETRDQLVQKGIWKGELYHDSIFKENSRGWLWKALLLCDENNNCLLTDNFKGLDLNQFGLVPVPMLADGDNYDENHNANVPKRVLHSNVSSSVGIRRLTPVEAVEKHPLSDDNDKTKGSLSKGSDEKPLTLRETLEIIDLDLSRIMLDDIFQEPKVHAQMRQLLYNYLLIHQSEHLQYKQGFHEILSVIYLQLYHGTDLDNTDLQNVLIIFNKLMNQIEPIFYNEENLINWDKRVFTKIFRICLPDLFSKVFYQPPKTGSGKKKNVDHLIHSNLIWLIRWTRLLFLRELPLKYVLIVWDHVLTFNYPLDIFIACTIITLLLSIYDELHELVSQGDYEHTNNNDEFVELILHFKKIFEKEDASKDDEKFLDLCKVTGNLCELWYGKNYDDMRLICDTFINAKFGIKTSDVLSMETAKLTIDPNRQSLENKLRERVRQTILKNKKKISQ
The following text describes a protein:
Function:
Acetylates the N-terminal alanine of ribosomal protein bS18.
Subcellular Localization:
Cytoplasm.
Sequence:
MSAMNAPMPTALRAMRESDLDAVMDIERRAYPFPWTRSIFRDCLQAGYPGWVLEQAGQIIGYGVISIAADEAHVLNVCIAPEAQSQGHGRVLLRALIKAACDRGARRAFLEVRPSNPSAIALYHSEGFNEIGRRPRYYPAHTGREDALVMAIELFFEGIS
The following text describes a protein:
Function:
Involved in cell cycle arrest when DNA synthesis is inhibited by hydroxyurea, and in mitosis arrest after treatment with DNA-damaging agents. This protein is S phase-specific.
Subcellular Localization:
Nucleus.
Sequence:
MMADESFDLESLGSDEIFEGVNLDELEQQAQTQVQAQSSQVVVPSEKQKQNLNLPNSYTNSSQKVRESTVNSQASLSSNDLRTELLIKSGENAILRANLLKQSEANNAALESLNNSIKQKQDEYQRKLEELKKEIEYAKTKSLFHEREAQDAIETMKKMKRDVKNSPIMKKSHEEDGDNKLLSSSDQLAKSTKHAAKNSPSKKKRKTSVATAEDASTDSVSSSIAISDASLSLSLMKDLLSLQKREDLYFSSRTLAYVFGGCMHSLETIEGEEEGECLFNNLKALIYSPDLSMDSSNYVQSVVQTSSSILNYSMKKLLYNASFAITSLFNALLILDPKSSTFIFQENVVSLISGFLLKEYEKSNFLDSKFYVLIDFLYLYLSIARESADDFANITKAVDPSLFESCIRVQNAPSLIKCGVCLIISSTTPSFCASVNLLNADDKSQESLMQLFTTMAHILVVTTRERINFPELNEWITLHRFVISFFTVFIQMSGNIGKEILKVCNPLIVCIGLAITWYHQQLLSSMYPQNECVEILVSLVRLLYILSSEDLSSKFMLAENALQPRFVYAIACCAFGDTEQKAFGNLGEEMYFLTTELLEVCVSPEELEQLYTNF
The following text describes a protein:
Function:
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.
Miscellaneous:
MISCELLANEOUS: Present with 172 molecules/cell in log phase SD medium; MISCELLANEOUS: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MYKTWRLCRTHTVGGLCHDGSHRFVSTGGAKIGKKFENMNQIRDYLSRPVWSVHEYLGINTKEEKLEPPSAEAVKKLLRLSGLPLEGADIKEIQMRLAKQLSFINKLHNIPVEGEKHTKEYDARLVQRNTKQLNYTKLLEGISHQKQDAELGEVSGSWKATGLAAESKNAYFVVKEGLLKNRK
The following text describes a protein:
Function:
Catalyzes the formation of 2'-nucleotide products from 2',3'-cyclic substrates. May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
Subcellular Localization:
Melanosome. Membrane; Lipid-anchor.
Sequence:
MNLKRRRRIIKNKYCPSSYADFPFLVDRPTISYLKKTYNKVVFILRGLPGSGKSYISNKIVRCYPLSSYVCSADFYFTSNKDGLYNICPEKLPEAHQLCKKSFFKATVVGKRHIIIDNTNIQRWEMDSYIKIANQHNYLVLIVEPKTPWKSNVEKLQKLNKHGCTSEYIECRKCLLHPITPYFWGFFVNEYESYLFTKFAEKNFYECLSLFKEFGNDLVSTYSKSLEYKMIYNVNFQKLLHCTTYFEKELKDLDSNEDSYSSQSDVIGSLGKHFKLTVSGFIFTPRTSGVLIKLDKKCLKIWKSEDAFMYKLDKDGKLIPSCSDEKTSCKDEISDAIYKKISLLSLNNELSKNRLCNVSEFIPVNQRIELKVGSRAHLTIGCTDGIEAVQTGFDVLSLKYKYLQSDCLKICYKNDCSYIYYGEGECKVLFDWPLQVESLFASYYQ
The following text describes a protein:
Function:
Translational regulator that ensures constant high levels of translation under amino acid starvation. Plays a role as a negative regulator of the GCN2 kinase activity; impairs GCN1-mediated GCN2 activation, and hence GCN2-mediated eIF-2-alpha phosphorylation in amino acid-starved cells and subsequent down-regulation of protein synthesis. In normal conditions, it resides in a actin complex and has no activity.
Miscellaneous:
MISCELLANEOUS: Present with 3030 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDDDHEQLVEELEAVEAIYPDLLSKKQEDGSIIVVKVPQHEYMTLQISFPTHYPSEEAPNVIEVGVCTSLAKRDLYDTKYLQHLFQEVMDSVFHRGSVCLFDFLTELDGVLYVEPEEETEPVQQSDIPTDPFEGWTASDPITDRGSTFMAFAAHVTSEEQAFAMLDLLKTDSKMRKANHVMSAWRIKQDGSAATYQDSDDDGETAAGSRMLHLITIMDVWNVIVVVARWFGGAHIGPDRFKHINSTAREAVVRAGFDS
The following text describes a protein:
Function:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC1 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Sequence:
MVQSQSGGHGPGGGKKDDKDKQKKYKPPVPTRVGKKKKKTEGSYAASKLPLVTPHTQCQLKLLKLERIKDCLLMEEEFIRNQKQMEPLEEKQEEERSKVDDLRGTPMSVGTLEEIINDNHATVSTSVGSECYVSILSFVDKDLLETGCLVLLNHKVHAMIGVLMDNMDPLVTVMKVEKAPQETYAGIGGWTTKFRKLRNLWIAEEYALSIMFIDEIDAIGTKRYDSNSGSEREIQRSALELLNQSDGFDSRGDVKVIMATNQIETLDPALIRPGCIDRKIEFPLHDENTKKCIFQIHTIRMTLANDVNLDDLIVTRDDLSGADIKAICTEVGLMALRECRMQVKNEDFQKSKENVLYKKQEVLMCLCFQSYLLQKIN
The following text describes a protein:
Function:
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells.
Miscellaneous:
MISCELLANEOUS: There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).
Sequence:
MSLHFGSQVFSSRSAAFPGRGTQVRLSSVRPGGFGSSSSLYGLGASRPRVAARSSYGAPVGTGIRAVTINQSLLTPLQVDIDPSIQQVRQEEREQIKTLNNKFASFIDKVRFLEQQNKLLETKWALLQEQKSAKSNRLPGIFEAQIAGLRKQLEALQLDGGRLEVELRNMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDVAYMNKVELEAKVDTLNDEINFLRTLYEQELKELQSEVSDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIANRSRAEAEACYQTKFETLQAQAGKHGDDLQNTRNEIADMNRAVQRLQAEIDSVKNQRSKLEAAIADAEQRGELAVKDARAKQEDLEAALQKAKQDMTRQLREYQELMNVKLALDIEIATYRKLLEGEESRLTGDGVGAVNISVVSSTGGSGSLLTFGGTMGNNALRFSSGGGPGTLKAYSMRTTSATSRSPRK
The following text describes a protein:
Function:
May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane.
Miscellaneous:
MISCELLANEOUS: Present with 5350 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MVPAESNAVQAKLAKTLQRFENKIKAGDYYEAHQTLRTIANRYVRSKSYEHAIELISQGALSFLKAKQGGSGTDLIFYLLEVYDLAEVKVDDISVARLVRLIAELDPSEPNLKDVITGMNNWSIKFSEYKFGDPYLHNTIGSKLLEGDFVYEAERYFMLGTHDSMIKYVDLLWDWLCQVDDIEDSTVAEFFSRLVFNYLFISNISFAHESKDIFLERFIEKFHPKYEKIDKNGYEIVFFEDYSDLNFLQLLLITCQTKDKSYFLNLKNHYLDFSQAYKSELEFLGQEYFNIVAPKQTNFLQDMMSGFLGGSK
The following text describes a protein:
Function:
May be required for ribosome biogenesis.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAKAGDKNGGGGKKGLKRKAATLEPQEAAVSEDGTTESGVQPTTAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETIVDPNDEEVAYDEATDEFASYFNRQTCPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCISRDFTDLIVINEDRKIPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHTPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFKSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL
The following text describes a protein:
Function:
Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane. Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins. Does not mediate insertion of beta-barrel transmembrane proteins (By similarity). Also acts as a receptor for the truncated form of pro-apoptotic BH3-interacting domain death agonist (p15 BID) and has therefore a critical function in apoptosis. Regulates the quiescence/cycling of hematopoietic stem cells (HSCs). Acts as a regulator of mitochondrial fusion, essential for the naive-to-primed interconversion of embryonic stem cells (ESCs). Acts as a regulator of lipid homeostasis and has a regulatory role in adipocyte differentiation and biology.
Subcellular Localization:
Mitochondrion outer membrane; Multi-pass membrane protein.
Sequence:
MADAASQVLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFCYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQYYQESEKPEELGSVTVQKEYSSSFDRVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIVTIYREEGIVGFFAGLIPRLLGDIISLWLCNSLAYLINTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGSPPYSPIYTSWIDCWCMLQKAGNMSRGNSLFFRKVPCGKTYCYDLRMLI
The following text describes a protein:
Function:
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein.
Sequence:
MAFSTQDSDEVLSEINVTPLVDVMLVLLVVFIVTAPLLTNSIPINLPKTESVAPPEQKDPLVVSIDGAGKLFVNKDEIQPELLESNLAAAKAKDAEVRVQLQADEGVNYGQVAKAMASIERAGITRLAVITAR
The following text describes a protein:
Function:
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Sequence:
MLPSIAKHAASHQINPLKKYGQNFIFDSSLCDKIVHASNLAENSRVLEIGPGTGGLTRSILQKKPESLTVIETDERCIPLLNEIKEYYPNLNIIKQDALKINLTDLSYDIVNSSKSIDYKVTIISNLPYHIGTELVIRWLKEARLINNMTLMLQKEVVERICAMPSTKAYGRLSVICQLIAKVEKCFDVAPTAFYPPPKVYSAIVKLIPLENPPSIALINKVEQITKLAFAGRRKMIKSSLKNLVPNIHEVLTQLKINDNYRAENLTPQDYLRIAEIL
The following text describes a protein:
Function:
Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
Sequence:
MNIGDDKSEVDVIIDSSSITLNNNESSNNNTNIGDVLKFESGLYNSFECELINQVFNSVPIMMGVCDLYDNSNSDFQIQDSQNYDFKFVISNRCSYDNLHMFLDKGKGLDGHYSAKELHLPAYFITLWIENMLRSLRKKKSVKFMYPRYVDNGETPSSDDFYSQKIVWKKSTMCFMGQVLVPLDDINSNSNNNSNQKQTACRFFFTSEEVTKEKFKKEELINDFKSRLETLENKIDQRVDERIETRFKYVLESIPQMVWVTDNHGKIEFVNRQWKDYLGIDHSGQYLNWGSISYQQHNNNNNNNNNNNNNNNNNNNNNSNNKSPIINSPNTTSPTNTQIDFDSQWHYSLKEMKRFEMEILLQSMSGEYRWFLVRAEPYIEPNLGHPSSPLPSIISACVDNCDIMTDDNSSGILINNNNNIQQPYLNNDNISGDNVNNTPTCIDNNNNNIDGSNNSVNSTGTEQLDIKWIGTCTDVNDQKTAQDRIENAEKSKALFLQTMSHEMRTPLAGIMGINSWLSTSSPQLTSEQLDGCHTIDMCAEALLVLINNILDLSKLEENKIILEETEFYPTKIVEDSVDILSSQAEQKKLDIIFQLKYNCLSKVVGDFYRIRQVLTNLISNSVKFTPANGQIIVGCEIYHETTPSTRKRSSLDSIEITIPCNHNNSNNSNNNHNHNNNNNNNNHLNCSGSFNNNGFNHGHHHHHHHHHHHHHHHDKHCDQKIIVPGKYGKLLFWVIDNGIGIPEEGREKLFQTFSQYDASTTRKYGGSGLGLAISKRLTQLLGGDIWFESQKGKGSSFHFLVEVFFPDYPTIYNQQLQQQQQQPNLPHQFNIGTSAPQPIDSILTSYSSNNSNNNINNNNITTSVISQSPIVDKSNLCTYIFLLSTNQVLVNSLSQWINEWIGNATNNNNSNNDNNNNNTTSTTTTTTTTTATINTNINQQVKILYDIDSIEQISNSAIQSGKRLDFLFLIEDTFWNNYSDKISNSQEIIESLINQNYQQQQQQQQEQRQQHNIKNVILSFSNSAQIYGNSIILKKPIKYSPLKDCIYTNLLYFKSIYSVNSFDVIIATQMSSSVSPSSLSSSPSIQGLTNSSLSINNINISGNNSNNNINNNNNNSGSSTPKKLKKSNSDQSIHFSPSLTSSSLPSLDLNNNNNINNNNNINNNNNINNNNNNNNNNNNNNNNNNNNLNHYNSDSILSSDLSPQQHQYHHPNPLLANYQKKRRNSVVNDTDIPLEMTGIRYPLKIMVAEDSLVNQKVACRFLTKLGYKKEEIIFVVNGQQAIDHIENVEMVDVILMDMQMPEVDGCEATTRIRMRYPTTGPHIIGLTANAFNEDKDKCLLSGMCHYLAKPVKMDILAVELKRAWLIRNKFRVCLCAVL
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Localization:
Nucleus.
Sequence:
MPSSSLSSPHPLVTAAILLETSLGELVVDLYGADCPVATAELVNLCRCKYFNGCIATEVVPDNVMILAHPVEELRRQTFASLLEASGQCHQLGGDTASDGRAVKQLIYNEWKRMRRHTAQLRRNSGASGKAEAGRLEFVPQSASNAVGAIRRSGLLLLEVPKVDGGGSNDEVSPKMQLLITLSNRHQDYFEDNFMVLGEVREGNNVVEKMRVAPHRRLTSVSGITTRPSRLIRIRHMTVLPTAGTDAFADISHRDRRKTMEENNLSSRLAQVGCFRHWATLGAVQAANKGLVSLLKREASKSTARKGRKGSSDETESFSGCEFLVIPEDSAQGGARNFPNHDTNNGDDYDILSVKYNSHFHGDYLSSDDDTDGDGNFGSRKEREKRQQEKMRLHQDKLNETRALTLNLLDGIGDASGELKPEGNVLFVCRLNPLTTSEGLEMCFSQFGKVKSVQVIRDSKTGDSLCYGFVEFADEETCYRAHQKMDNALIDDRRIHVDFSQSVSKLWMEKQRELRKRVRQ
The following text describes a protein:
Function:
May play a photoprotective role in the thylakoid membrane in response to light stress (Probable). Involved in photosystems I (PSI) and II (PSII) core proteins function. Forms a trimeric complex with OHP2 and HCF244 that is required to promote PSII core subunit assembly. The trimeric complex forms a transient PSII reaction center-like complex with PsbA, PsbD, PsbE, PsbF and PsbI subunits in thylakoids for early assembly of PSII as well as PSII repair. The trimeric complex is required for the recruitment of ribosomes to the psbA mRNA during PSII biogenesis and repair. Forms a heterodimer with OHP1 that binds chlorophylls and carotenoids, and that may function in the delivery of pigments to the PsbA subunit of PSII.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein. Note=Associated with both photosystems I and II.
Sequence:
MSSSPLSSSLFHPLSTLSTHCHGRRQNLCFNRKQQPFVVRAAKLPEGVIVPKAQPKSQPAFLGFTQTAEIWNSRACMIGLIGTFIVELILNKGILELIGVEIGKGLDLPL
The following text describes a protein:
Function:
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
Miscellaneous:
MISCELLANEOUS: [Isoform 1]: Mitochondrial. Produced by alternative splicing; MISCELLANEOUS: [Isoform 2]: Cytoplasmic. Produced by alternative promoter usage; MISCELLANEOUS: [Isoform 3]: Cytoplasmic and nuclear. Produced by alternative promoter usage; MISCELLANEOUS: [Isoform 4]: Produced by alternative splicing; MISCELLANEOUS: [Isoform 5]: Cytoplasmic. Produced by alternative initiation.
Subcellular Localization:
[Isoform 1]: Mitochondrion; [Isoform 2]: Cytoplasm; [Isoform 3]: Cytoplasm. Nucleus; [Isoform 5]: Cytoplasm. Membrane; Lipid-anchor.
Sequence:
MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEVCSEKTGHAEVVRVVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQKVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVSCPVGIKK
The following text describes a protein:
Function:
Multifunctional aminotransferase with a broad substrate specificity. Catalyzes the conversion of glyoxylate to glycine using alanine as the amino donor. Catalyzes metabolism of not L- but the D-isomer of D-beta-aminoisobutyric acid to generate 2-methyl-3-oxopropanoate and alanine. Catalyzes the transfer of the amino group from beta-alanine to pyruvate to yield L-alanine and 3-oxopropanoate. Can metabolize NG-monomethyl-L-arginine (NMMA), asymmetric NG,NG-dimethyl-L-arginine (ADMA) and symmetric NG,N'G-dimethyl-L-arginine (SDMA). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure.
Subcellular Localization:
Mitochondrion.
Sequence:
MPATSFQPQPYEGPDFDKIRSIRANHLNPALFTYYKSPLLIHQGHMQWLFDHNGVRYLDLFGGIVTVSVGHCHPKINEATKKQLDKVWHTTNIYLHPKIHEYAERLVATLPGDLKVVYFVNSGSEANDLAMMMARMYTGCYDLISFRNAYHGMSPATNGLTAHSTWRYNIAGNFGIHQTMNADPYRGEWGGKHCRDSPVQTTRSCNCSPGQCAASGKYVDQLDEVLRYSAPKGRVGGFFAESIQGVGGTVQYPKGFLKSAFELIRNHGGVCIADEASVQTGFGRTGEHFWGFEGHGAIPDIVTMAKGMGNGYPMAAVVTTPAIAKTMSAALHFNTFGGNPVASTVGMAVLDAIEADQTQANCRDVGTYFLLELAKLRDEFPNLVGDVRGKGLMIGVELVSDPETRAPLAPADVLTIWEQCKDMGVLYGKGGFYGNVFRIKPPMCITKSDVDFAVAVLRKSIASFLEK
The following text describes a protein:
Function:
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
Subcellular Localization:
Nucleus.
Sequence:
MAPLKNLEQDYTIIDSNFLNFCASHGIFSVEDFLIHDLYKLAAFAEQNISSERLKEGITQVLSIIDDMHQPWLNGMELLEDAKRNKHSLPTGIQGIDFLLGGGIRVGQLTELVGPSSSGKTQVCLQTASNVVSNHMGTVVYLDTGNSFSPQRIAHFLGVTNDLASSEIKNQILQRVMSNILCHSVFDIFEMFDVLHKLEYQLRSQDRGGCQMRLLIIDSISLLITPVLGGTSSQGRALMVSAGYLLKKLADQHNLAVLVTNHTVGGEGGTSKPALGESWKSIPHSRLLLSCDRGSNVCNVSILKHPSMASGEAARSELRGRDCNHEARVDVKGQHFQLLPFGTGRRDCLGISLALQELATVVAAIIQCFDLKVFTQVVTPDGMKSCGRDVVDMTDRPGLTAPRSLESQDSLSNLKKWKKPDPNWPTPGSITTLILCFFFSSSSYSFLFSFWDNSALHILFPIFSQFFMGIKTFFSLLMFHSSSRVSRPINQIQRILVKHFVIIHRHSKHYHTFGPKKPTTKPDHETPQKTTKNRRRKWPPNPFVTNLKEIQEPDEALSLFHEYYQMGYKHDYPSYSSLIYKLAKSRNFEAVETLLGYLQNLNIHCQETLFNALFESYGKARLIEKAIELFHKMPSFNCVRTVQSLNSVLNALVDNDRFFDAKVIFDKSPKMGFRPNSTTFNVMIKGLLKREAFDEACCLFDEMLERNVEPSVVTYNSFIGFLCKKGEMENAEGLVEDMVKKGKYPNAVTYALLMEGLCSLGKYKEAKKLMFDMEYKGCKTKVINFGVLMTYLGKRGEIEEAKSLLREMKKRRFKPDVVIYNILVNYLCKEGRVGEAYKVLIEMQVKGCEPNAATYRMMVDGFCMVGDLEGALKVLNVMFTSGHCPRLETLCQLVTGLLKCGKIDGACFVLEEMEKRKMSFDLEAWGALVRDACGGDDTNDLQTQLILVASD
The following text describes a protein:
Function:
Na+/H+ exchanger which mediates the transient acidification of the coelomic space and plays a role in contraction of posterior body muscles during defecation. Probably by regulating the defecation motor program, required for fatty acid uptake by intestinal cells.
Subcellular Localization:
Basolateral cell membrane; Multi-pass membrane protein.
Sequence:
MWIKLLFFFTTLLVSTSGLGDDGITALLDPNSTEFSTVLPSNNSEKFSYMLASVKNMNMTASEFEEFIKVLKHRQSKDHSGEHVGNEHDESHGISVVSWHWDYVKNELVLTLFFIVIGLFKLVYHHTFVTRKILPESCCLIFIGIAIGFFFVGDATHASIKFLEFKSKVFFFYLLPPIILESAYSLKDRAFIENIGTILLYAVVGTILNIVLLAAALLILIWVGIMGKYNLSVMDILTFASLVAAVDPVAVLAVFQEVGVNKMLYFMVFGESLFNDAVTIVCYNLAIEFQTLPDFTWYHGFLGLLSFLCVSIGGLIIGLICGAISSFVTKFTTDVRVVEPVVLFGMAYLAYLGSEMFHFSGIIALIACGLFQTHYACCNISYKSFTSVMYITKVCSTLCESLIFIILGVMLVNEREWFWTDWHPVFSAVSVVLCVVVRFGVTFFLTYFVNQFTGGVRHISFQEQFIMSYGGLRGAVSFSLVFMISANPDVKNTMLGATYAVILFTNIIQGSTIKLFVKWLNIRLAKKEDHFRLFIEFNNGMVQHLSQGIEDLCGDKSLSLINRMSELSKKYVRPLLEKNYTANKAKKEGKLVELNRAVAMREALNNSPSQSSFQRQHTIDEMAESGALPHDLLDEEHQGHHHHGQVHPDNEDADQRANELIKDVSSIRQLMHNPFEDCYLDRNLTHEEEKEQARLKMKKTRAFKFSSVRKTIGFFGKKKSVRRHATQQGILHSAIATIGVQSVDRPSTSTRVSVEDEEQGLTMKEMEEEHPLMTITESEETSF
The following text describes a protein:
Function:
Required for nuclear membrane fusion during karyogamy.
Subcellular Localization:
Endoplasmic reticulum membrane. Nucleus membrane.
Sequence:
MLELKRLEEEPICHRVAAQLLMSNCEGLEDINQKEYDLYSGRIQRHYVESLAASLAICDMERSSMVVPDSCEPFRLPSLLRASQEADGKLQVSQNEVGACLKGLGKDPSHWLSWTSYRDNCLLICQAARSDIDKDQSILLQKKLVEIMRQFAEDLEYDLQDLKRNVADHARAAGSYFEEVMMRTEVLKTKVEGAFEVISSEALDLLIPVITSMSDRQDTLDQRFEALSNVVINMTTLIQDHSESLGQASFTVTGIRESLGKAAEAANSWNGIMGMGEPFVNNALRILSPPVTLFFGSHGLPPSLFRNFGLLVGGWAVAETTIQLRQTEHWIPRIQRPRASTQLARDRVLQEEAQITFGTSSSHNGIGSIKKAHTGGMK