lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Specifically methylates the guanosine in position 748 of 23S rRNA. Confers resistance to the macrolide antibiotic tylosine.
Sequence:
MRKNVVRYLRCPHCAAPLRSSDRTLRCENGHTFDVARQGYVNLLRRPTKLAADTTDMVAARAALLDSGHYAPLTERLAGTARRAAGAGAPDCVVDIGGGTGHHLARVLEEFEDAEGLLLDMSKPAVRRAARAHPRASSAVADVWDTLPLRDGAAAMALNVFAPRNPPEIRRILRPGGTLLVVTPQQDHLAELVDALGLLRVRDHKEGRLAEQLAPHFEAVGQERLRTTLRLDHDALGRVVAMGPSSWHQDPDELARRIAELPGIHEVTLSVTFTVCRPLP
The following text describes a protein:
Function:
Involved in mitochondrial genome encoded proteins translation. Involved in the binding of tRNA to the ribosomes.
Sequence:
MLSSISSFRLLRLSSATLPRRNYYSVLAPTEPSQPSSTDPSQTETDRQQSNSIEDYVTQLAGSSSSISSPVRPPQSTSQAKELIHIPANPGWAMRAHPELYDPPVLKPTHRIHVATLVIEAYNPEKEQLPLVAGFALQAAYHLGIPVTRPAAMPIKTELHTVLRSGFVHKKSQENFWRLTHRRVIKAYDANEEVINRWINYLRTDAVRGTNVALKAQRFLYRPIGWGKDVDELARRELELEQLEKPKSTNGRKKSARARANLSSSSTQAELTQAEAVKALAERLIKEELIPKAEAHEAMLASTGTKDGKKMAELQIKDSDNNNK
The following text describes a protein:
Function:
Catalyzes the hydrolysis of dihydroneopterin triphosphate to dihydroneopterin monophosphate and pyrophosphate. Required for efficient folate biosynthesis. Can also hydrolyze nucleoside triphosphates with a preference for dATP.
Sequence:
MKDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVEEGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESWFCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA
The following text describes a protein:
Function:
Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons 9 and 10 of the acyl chain. Converts palmitoyl-ACP to (4Z)-hexadec-4-enoyl-ACP by introduction of a cis double bond between carbons 4 and 5 of the acyl chain. Catalyzes the desaturation of saturated fatty acid 18:0 and 16:0 to generate 18:1 (delta-9) and 16:1 (delta-4) intermediates, expected to give rise to 9-alkenes and 12-alkenes, respectively.
Miscellaneous:
MISCELLANEOUS: Flowers 9-alkenes and 12-alkenes function as attractants to the pollinator Andrena nigroaenea by mimicry of the bee's sex pheromones.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MELHLALRASPLPAADPGRRPPPPRGNFATNCTAAINSTHISQEKFRSLDSWVEHNMLTFLKPVEKCWQPQDFLPDPSHLSAEELGDAVREIHERAAEIPDEVWVCMVGNMVTEEALPTYQSLISSVLGGTVAGSTPWDRWIRGWSAEENRHGDLLNKYLYLTGRLDMRQVEKTIQYLIGSGMDVGVGNSILCGFIYTCFQEKATFISHGNTARLAKHHGDTTLAKICGLVAADEKRHAVAYTNLMKKLFEVAPNESMLAFAHIMRAHVTMPASRMFDGRDPRLFTHFSAVTQKIGVYTVRDYGEMLDFFLKEWEISAVVDDLSPEGRQAQEYVCGLPEVMGKMAERADDRRKKLVNVGEPRYIPFSWIFNKQVCV
The following text describes a protein:
Function:
Disease resistance (R) protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Contribution of Pik-1 is required to recognize the effector avirulence protein AVR-Pik.
Sequence:
MELVVGASEATMKSLLGKLGNLLAQEYALISGIRGDIQYINDELASMQAFLRDLSNVPEGHSHGHRMKDWMKQIRDIAYDVEDCIDDFAHRLPQDSISDAKWSFLLTKIYELWTWWPRRVIASNIAQLKVRAQQIADRRSRYGVNNPEHLDSSSSARTRAVNYEIAEYQVTSPQIIGIKEPVGMKTVMEELEVWLTNPQAENGQAVLSIVGFGGVGKTTIATALYRKVSEKFQCRASVAVSQNYDQGKVLNSILSQVSNQEQGSSTTISEKKNLTSGAKSMLKTALSLLRGNCICQPENDGNPDNTPIRLQETTDDDQNPRKLEQLLAEKSYILLIDDIWSAETWESIRSILPKNNKGGRIIVTTRFQAVGSTCSPLETDRLHTVDFLTDDESQNLFNTSICESKIRKDSNKVDEQVPEEIWKICGGLPLAIVSMAGLVACNPRKACCDWSKLCKSLFPEQETPLTLDGVTRILDCCYNDLPADLKTCLLYLSIFPKGWKISRKRLSRRWIAEGFANEKQGLTQERVAEAYFNQLTRRNLVRPMEHGSNGKVKTFQVHDMVLEYIMSKSIEENFITVVGGHWQMTAPSNKVRRLSMQSSGSNRGSSTKGLNLAQVRSLTVFGNLNHVPFHSFNYGIIQVLDLEDWKGLKERHMTEICQMLLLKYLSIRRTEISKIPSKIQKLEYLETLDIRETYVRDLPKSIVQLKRIISILGGNKNTRKGLRLPQEKSKKPIKNPSPQGKTKEPAKKGFLSQEKGKGAMKALRVLSGIEIVEESSEVAAGLHQLTGLRKLAIYKLNITKGGDTFKQLQSSIEYLGSCGLQTLAINDENSEFINSLGDMPAPPRYLVALELSGKLEKLPKWITSITTLNKLTISVTVLRTETLEILHILPSLFSLTFAFSLSAAKQDQDIIKDILENNKLDSDGEIVIPAEGFKSLKLLRFFAPLVPKLSFLDKNAMPALEIIEMRFKDFEGLFGIEILENLREVHLKVSDGAEAITKFLVNDLKVNTEKPKVFVDGIVTA
The following text describes a protein:
Function:
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Sequence:
MVQKKTTEMKGFHRSFKGQNPFDAAYEMEARNMSSVFNFDCPSRPDVPSSAPIDIPDAKKRTKKKKRCRATDSFTGRFEDIYQLQQEILGEGAYAKVQSCINLINNKEYAVKIIEKRPGHSRSRVFREVEMLYQCQGHSNVLELIEFFEEEDKFYLVFEKMCGGSILNHIHRRRHFNEREASFVVRDIAEALNYLHNKGIAHRDLKPENILCESPHQVSPVKICDFDLGSGIKLNSDCSPISTPELLTPCGSAEYMAPEVVEAFNEEASIYDKRCDLWSLGVILYIMLSGYPPFVGHCGSDCGWDRGEACPTCQNMLFVSIQEGKYEFPEKDWAHISTGAKDLISKLLLRDAKKRLSAAQVLQHPWVQGNAPDNTLPTPIILQRNSSAKGLTSFAAEAIAMNRQLMEREEEEEGTESSLSCPIVVKATSCSMQLSPPSESKLAKRRQQGSKGGLSPPSLAPLLIVSD
The following text describes a protein:
Function:
Plays a role in phenanthrene catabolism. Catalyzes the transformation of trans-2'-carboxbenzalpyruvate to 2-formylbenzoate and pyruvate.
Sequence:
MTSPAVTSADITGLVGIVPTPSKPGSEAPDAVDTVDLDETARMVELIVASGVDVLLTNGTFGEVATLTYEELLAFNDTVIRTVANRIPVFCGASTLNTRDTIARSLALMGLGANGLFVGRPMWLPLDDEQLVSYYAAVCDAVPAAAVVVYDNTGVFKGKISSAAYAALAEIPQIVASKHLGVLSGSDAYASDLAAVKGRFPLLPTADNWLPSLEAFPGEVPAAWSGDVACGPEPVMALRRAIAEGLWDDARAVHEDIAWATEPLFPGGDISKFMPYSIQIDRAEFEAAGYIVPGPSRHPYGTAPAAYLEGGAEVGRRWAGIRQKYVATLAEP
The following text describes a protein:
Function:
An RNA-guided dsDNA endonuclease. When guided by an RNA derived from the right-end element of its insertion sequence element (IS), cleaves DNA downstream of the transposon-associated motif (TAM). Cleaves supercoiled and linear DNA in a staggered manner 15-21 bases from the TAM yielding 5'-overhangs. Binds reRNA, an approximately 150 nucleotide base sRNA derived from the 3' end of its own gene, the right end (RE) of the insertion sequence (IS) plus sequence downstream of the IS.
Sequence:
MMARLKVPEGWCVQAFRFTLNPTQTQAASLARHFGARRKAFNWTVTALKADIKAWRADGTESAKPSLRVLRKRWNTVKDQVCVNAQTGQVWWPECSKEAYADGIAGAVDAYWNWQSCRAGKRAGKTVGVPRFKKKGRDADRVCFTTGAMRVEPDRRHLTLPVIGTIRTYENTRRVERLIAKGRARVLAITVRRNGTRLDASVRVLVQRPQQRRVALPDSRVGVDVGVRRLATVADAEGTVLEQVPNPRPLDAALRGLRRVSRARSRCTKGSRRYCERTTELSRLHRRVNDVRTHHLHVLTTRLAKTHGRIVVEGLDAAGMLRQKGLPGARARRRALSDAALATPRRHLSYKTGWYGSSLVVADRWFPSSKTCHACRHVQDIGWDEKWQCDGCSITHQRDDNAAINLARYEEPPSVVGPVGAAVKRGADRKTGPGPAGGREARKATGHPAGEQPRDGVQVK
The following text describes a protein:
Function:
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
Subcellular Localization:
Cytoplasm.
Sequence:
MPDTEEVKPETTTEAAAPQSADKAVAETPDTTVEAATSEAADPAAVIADLQNRLAQAEAQAAEYKDQWMRAVADYRNFKRRTETERTELVRNAGAALILKLLPVLDDFERAIANIPPDIAETPWWQGTQLIAQKLRTILESEGVKPIEALGQEFNPNLHEAVIYEDAEGQEGKVIAELQRGYLLHDRVIRPSMVKVGRG
The following text describes a protein:
Function:
Probable ubiquitin-protein ligase involved in the degradation-related ubiquitination of histones. Contributes to the post-translational regulation of histone protein levels by polyubiquitination of excess histones for subsequent degradation.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Localizes to DNA double-strand breaks (DSBs).
Domain:
Members of the RBR family are atypical E3 ligases. They interact with the E2 conjugating enzyme UBE2L3 and function like HECT-type E3 enzymes: they bind E2s via the first RING domain, but require an obligate trans-thiolation step during the ubiquitin transfer, requiring a conserved cysteine residue in the second RING domain.
Sequence:
MSDLLDDEFYEEEFENDLLDASEFEDEFDEDAEIDDDGFTVERKRRRAHSVSYRVVSVRDLRASLNEKINQLTSIIDLTREQVLGLYRYFKWNRERLLERYIDAPEESLQKAGVGLSGSKQREVVHHEGTCEICYDEGCLPFFSAECDHEFCLACYRQYLDSRISEGESVIQCPEESCTQIVSIQSITKVLDEKSLDRYHRLLDRSFVDDNDHLRWCPAPDCEFAIECHVTQASLSSVVPTVTCNCGKQFCFGCGHDNHQPTICPLVKIWLQKCQDDSETANWIHANTKECPKCSTTIEKNGGCNHMTCKKCKYEFCWVCLGPWTEHGNNWYTCNRYEEKSSTSARDSQSKSRASLERYLHYYNRFANHEQSAKLDHELYEHTHKRMTQMQVDSNLSWVEVQFLKNAVDILFQCRQTLKWTYAFAYYLARNNQTEIFEDNQRDLELAVENLSELCERPCQDCSLSVFKQRVLDKTVYVRSRRDVLLDDTARGLAEGRWEYVVDV
The following text describes a protein:
Function:
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).
Subcellular Localization:
Cytoplasm.
Sequence:
PQGCSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPGLGLRLFRHFDPFRILICSGDGSIGWVLSEIDKLHMDKQCQIGVLPLGTGNDLARVIGWGSVCDDDAHLPQLLERYEKASVKMLDRCVSHLLSFFFDSHPPRVDEEDPPNNCVMNSYFGIGIDAKITLDFHMKREEHPEKCRSRARNYMWYGVLGSKEWLQKTYKNLEQRVLLECDGTRIPLPSLQGIVVLNIPSFMGGTNFWGGNKEDDCFIAPSFDDRVLEVVAVFGSVQMAASRIINLQHHRIAQCHSVKITILGDEGVPVQVDGEAWLQPPGLIRIVHKNRMQMLCRNRVLQIPFD
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MRRTISVLVQPRCLLLYLVLFVLLIFAFSKPKTKTKTKIKQVEEKAEEVPEITHRVYLDVNIDKQRQGRIVIGLYGQVVPKTVENFRALCTGEKGKGASGKKLHFKGTPFHRIVSGFMIQGVVSMVNSGPNSNGAQFFITTVKTSWLDGEHVVFGKVIQGMDIVFAIEGGAGTYSGKPRKKVVIAESGEIPKSKWDEES
The following text describes a protein:
Function:
Odorant receptor; Putative odorant or sperm cell receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
STFPQHLLPIFFFLYLLMYLFTLLGNLLIMATIWSERSLHTPMYLFLCALSISEILFTVAVTPRMLVDMLSTHHSITFVACASQMFFSFTFGFTHSFLLMIMGYDCYVGNCHPLCYNVLMGTQGCASLMFWSWAGGSVMGMMVTLIVFHLTFCGSNMIHHFACYVLPLLKLSCGRETSSVTLGVILVCVTALMGCLFLIFLSYVFIVATILRIPSAEGRHKTFSTCVSHLTVVVVHYGFASIIYLKPKGPHSMDSNTLMATTYTVFTPFLSPIIFSLRNRELKNAIKKMRLQKTLSCELLTNSLEVRNYDRRAEIMICPHKAVVRAQVCENTYTP
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MDNNNWRPSLPNGEPAMDTGDWRTQLPPDSRQKIVNKIMETLKKHLPFSGPEGINELRRIAARFEEKIFSGALNQTDYLRKISMKMLTMETKSQNAAGSSAAIPAANNGTSIDSIPTNQGQLLPGSLSTNQSQAPQPLLSQTMQNNTASGMTGSTALPSSMPPVSSITNNNTTSVVNQNANMQNVAGMLQDSSGQHGLSSNMFSGPQRQMLGRPHAMSSQQQQQPYLYQQQLQQQLLKQNFQSGNVPNPNSLLPSHIQQQQQNVLQPNQLHSSQQPGVPTSATQPSTVNSAPLQGLHTNQQSSPQLSSQQTTQSMLRQHQSSMLRQHPQSQQASGIHQQQSSLPQQSISPLQQQPTQLMRQQAANSSGIQQKQMMGQHVVGDMQQQHQQRLLNQQNNVMNIQQQQSQQQPLQQPQQQQKQQPPAQQQLMSQQNSLQATHQNPLGTQSNVAGLQQPQQQMLNSQVGNSSLQNNQHSVHMLSQPTVGLQRTHQAGHGLYSSQGQQSQNQPSQQQMMPQLQSHHQQLGLQQQPNLLQQDVQQRLQASGQVTGSLLPPQNVVDQQRQLYQSQRTLPEMPSSSLDSTAQTESANGGDWQEEVYQKIKSMKETYLPDLNEIYQRVAAKLQQDSMPQQQRSDQLEKLRQFKTMLERMIQFLSVSKSNIMPALKDKVAYYEKQIIGFLNMHRPRKPVQQGQLPQSQMQPMQQPQSQTVQDQSHDNQTNPQMQSMSMQGAGPRAQQSSMTNMQSNVLSSRPGVSAPQQNIPSSIPASSLESGQGNTLNNGQQVAMGSMQQNTSQLVNNSSASAQSGLSTLQSNVNQPQLSSSLLQHQHLKQQQDQQMQLKQQFQQRQMQQQQLQARQQQQQQQLQARQQAAQLQQMNDMNDLTSRQGMNVSRGMFQQHSMQGQRANYPLQQLKPGAVSSPQLLQGASPQMSQHLSPQVDQKNTVNKMGTPLQPANSPFVVPSPSSTPLAPSPMQVDSEKPGSSSLSMGNIARQQATGMQGVVQSLAIGTPGISASPLLQEFTSPDGNILNSSTITSGKPSATELPIERLIRAVKSISPQALSSAVSDIGSVVSMVDRIAGSAPGNGSRASVGEDLVAMTKCRLQARNFMTQEGMMATKKMKRHTTAMPLSVASLGGSVGDNYKQFAGSETSDLESTATSDGKKARTETEHALLEEIKEINQRLIDTVVEISDDEDAADPSEVAISSIGCEGTTVRFSFIAVSLSPALKAHLSSTQMSPIQPLRLLVPCSYPNGSPSLLDKLPVETSKENEDLSSKAMARFNILLRSLSQPMSLKDIAKTWDACARAVICEYAQQFGGGTFSSKYGTWEKYVAAS
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Sequence:
MQRQKSLLSFFQKSPSDNRSSDGCASSVGQRLTRFQTKPSAAGLEQPAIQTTADSSLEIRGTDTPPEKVPRQILPVIEKNRGSSLFSSIMHKFVRVDDKRKANERDEVQKDSSQNEVGKDSPQLPSISGKVNDPTEFSKLDVASRRHGKFDVANLNGHRGPVLNIESNEDIAGPETPGMRPSVSRLKRSQEVSLVNCSGDSLQDSTKRIKLLQDSINLNKIHNEISDATSKFEWLNPSQVRDANRRRPDHPLYDKKTLYIPPDVLKKMSASQKQYWNVKCQYMDILLFFKVGKFYELYEQDAEIGHKELDWKMTLSGVGKCRQVGVPESGIDEAVQKLVARGYKVGRVEQLESAEQTKSRGANSVIPRKLVQVTTPSTKADGDIGPDAVHLLAIKEESCGLDNNSISYGFAFVDCAALKFWTGSIKDDASCAALGALLMQVSPKEIIYEARGLSKETHKVLKKYSPTGSTALELTSGSPVTNFLEASEVKLLVQSKAYFKGSLNLWNHESTVHDDIALCALGGLINHMSRLMLDDVLRNGDLLPYQVYRGCLRMDGQTMVNLEIFRNNDDGGLSGTLYKYLDNCVTSSGKRLLRLWICHPLKDVEEINNRLNVVEELMAQSDIMVLLGTTYLRKLPDLERLLGQIKATVQSSASLVLPLIRKKLQKRRVKLFGSLVKGLRTGLDLLIQVQKEGLIISLPKVVKLPQLSGNGGLDQFLTQFEAAVDSEFPDYQNHDVTDSGAERLSILIELFVEKATEWSEVIHALNCVDVLRSFAIIAHSSRGSMSRPLILPQSNNSMLSPEKQGPVLKINGLWHPYALVESGETPVPNDMILGLDQDSYHPRTLLLTGPNMGGKSTLLRSTCLAVVLAQLGCYVPCETCTLSVVDTIFTRLGATDRIMTGESTFLVECSETASVLQHATQDSLVILDELGRGTSTFDGYAIAYAVFRHLIEKVNCRLLFATHYHPLTKEFASHPHVMLQHMACTFKDHELIFLYRLRSGACPESYGLKVATMAGIPGRVVEAASRASQMMKQTIKENFKSSEQRSEFSTLHEEWLKTLITVLEFKGNNLGENDAFDTLFCLWYELKRDRITARI
The following text describes a protein:
Function:
Required for regulation of peroxisome size and maintenance. Has a role in the import of peroxisomal matrix proteins. Imports RHO1 into the peroxisome. Also promotes peroxisome division and biogenesis.
Miscellaneous:
MISCELLANEOUS: Present with 2420 molecules/cell in log phase SD medium.
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MSQFGTTDIVSGSETPPYSGASYQDAQDDNTHPHSSDAGAEKFSAGSGSESHTESSRSDDEDSQAKTKMVDNITILKYILDSLSGRDKLAKIIKYALDILKLFIEKSKRNLTVLDPSVLTYYTKILKNLTVKVALRHPITVIKVLLLSLLRNFDKKIDFISQQLSTFRYILRFGGTPFRVCSFLGKFNKTRKCNFQIDQIKKIWFNEASLREFLDLYYGIFDELDLLYKLKIWTNKSFYSFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQLELEVQLKVQNNALLLSPILMHQAHKDDGSQSPIRKQLLNDLNVNNDAEVLIHKQLKAIKDEKTLVYLDIARLSFDCMANTSDILNLKTPKGTYAVLSLGSGLTGLVKLWITTKRSLCSSKD
The following text describes a protein:
Function:
Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
Miscellaneous:
MISCELLANEOUS: Defined as class II fido-domain containing proteins, in which the inhibitory helix is present at the N-terminus of the Fido domain.
Sequence:
MEWQAEQAYNHLPPLPLDSKLAELAETLPILKACIPARAALAELKQAGELLPNQGLLINLLPLLEAQGSSEIENIVTTTDKLFQYAQEDSQADPMTKEALRYRTALYQGFTQLSNRPLCVTTALEICSTIKSVQMDVRKVPGTSLTNQATGEVIYTPPAGESVIRDLLSNWEAFLHNQDDVDPLIKMAMAHYQFEAIHPFIDGNGRTGRVLNILYLIDQQLLSAPILYLSRYIVAHKQDYYRLLLNVTTQQEWQPWIIFILNAVEQTAKWTTHKIAAARELIAHTTEYVRQQLPKIYSHELVQVIFEQPYCRIQNLVESGLAKRQTASVYLKQLCDIGVLEEVQSGKEKLFVHPKFVTLMTKDSNQFSRYAL
The following text describes a protein:
Function:
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MARGEGAEQFSSGLLPTAKSVTQNEIKMVKLPKQQERKRALTVWSKVCFAIGGAPYQITGTALGFFLQIFLLDVAQLNPLNASVILFVGRAWDAVTDPTVGFLVSRTPWTRHGRMMPWILVSTIPAVLCYFLIWVVPPIEQGKMMWYLLFYCLFQTLQTCFHVPYSALTMFISTEQRERDSATAYRMTVEVFGTVVGTAIQGQIVGMANTPCKNNTSPNNSSNDLIQSNNSHIPLKSNIFDERCAYMIASAVISLIYVVCAAVLFFGVREQDVQGELKAQKRVSFQKGLRLVMGHGPYVKLVLAFLFTSLAFMLLEGNFAVFIKYTLGFREDFQNILLVIMVSATVSIPMWQWFLCRFGKKTAVYIGITWAVPFMILVVSVNSSLIVSYIVSIAAGVSVGAAFLLPWSMLPDVVDDFKLQNPTSQGHEAIFYSFYVFFTKFASGVSLGVSTLALSFAGYETGVCVQSDSVNLTLKLLVSAAPVSLIALGLLIFMTYPIDEERREYNNKQLQLLLRNEEEEDEMEVLKPDITA
The following text describes a protein:
Function:
Endonuclease for the repair of UV-irradiated DNA. Involved in the excision of cyclobutane pyrimidine dimers (CPD) and 6-4 pyrimidine pyrimidones (6-4PP) which forms the UV damage repair (UVDR) pathway.
Sequence:
MPSRKSKAAALDTPQSESSTFSSTLDSSAPSPARNLRRSGRNILQPSSEKDRDHEKRSGEELAGRMMGKDANGHCLREGKEQEEGVKMAIEGLARMERRLQRATKRQKKQLEEDGIPVPSVVSRFPTAPYHHKSTNAEEREAKEPVLKTHSKDVEREAEIGVDDVVKMEPAATNIIEPEDAQDAAERGAARPPAVNSSYLPLPWKGRLGYACLNTYLRNAKPPIFSSRTCRMASIVDHRHPLQFEDEPEHHLKNKPDKSKEPQDELGHKFVQELGLANARDIVKMLCWNEKYGIRFLRLSSEMFPFASHPVHGYKLAPFASEVLAEAGRVAAELGHRLTTHPGQFTQLGSPRKEVVESAIRDLEYHDELLSLLKLPEQQNRDAVMIIHMGGQFGDKAATLERFKRNYARLSQSCKNRLVLENDDVGWTVHDLLPVCEELNIPMVLDYHHHNICFDPAHLREGTLDISDPKLQERIANTWKRKGIKQKMHYSEPCDGAVTPRDRRKHRPRVMTLPPCPPDMDLMIEAKDKEQAVFELMRTFKLPGFEKINDMVPYDRDDENRPAPPVKAPKKKKGGKRKRTTDEEAAEPEEVDTAADDVKDAPEGPKEVPEEERAMGGPYNRVYWPLGCEEWLKPKKREVKKGKVPEEVEDEGEFDG
The following text describes a protein:
Function:
Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
Subcellular Localization:
Endomembrane system. Membrane; Multi-pass membrane protein.
Sequence:
MVYFPLPSPATALTVPKLGEADGIFLSLVLPTYNEGENIQAMVTTLVKLLENRWSGQYELIVVDDDSPDLTWQKAFNLSDTYPQLRVIRRTEGRGLSTAVIRGWQEARGNFLGVIDADLQHPPQVLLALLAEMERGADLAVASRHQSGGGVSQWSLVRRLLSRGAQMLGLLILPEVIGRLSDPMSGFFLVRRQAIADCPLSPVGYKILIEVTARGRIRWLAEVGYVFQERRSGQSKVTWRQYVEYLQHLCKLRLSLSSRFLQFCAVGLTGVAVDMAILFILTEPSLGDLPLSRSKIIAAQLAILNNFFWNDRWTFQDLTQGQNSPSQVSKRLLKFNLICWAGLGINLGLLNFFFNFSHFNRYLANALAIALVTLWNFWFNLKLSWRVTDV
The following text describes a protein:
Function:
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. Does not appear to be essential for chromosomal replication. May be involved in generating antibiotic resistance.
Subcellular Localization:
Cytoplasm.
Sequence:
MFDILWNVGWSNGPPSWAEMERVLNGKPRHAGVPAFDADGDVPRSRKRGAYQPPGRERVGSSVAYAELHAHSAYSFLDGASTPEELVEEAARLGLCALALTDHDGLYGAVRFAEAAAELDVRTVFGAELSLGATARTERPDPPGPHLLVLARGPEGYRRLSRQLAAAHLAGGEKGKPRYDFDALTEAAGGHWHILTGCRKGHVRQALSQGGPAAAQRALADLVDRFTPSRVSIELTHHGHPLDDERNAALAGLAPRFGVGIVATTGAHFADPSRGRLAMAMAAIRARRSLDSAAGWLAPLGGAHLRSGEEMARLFAWCPEAVTAAAELGERCAFGLQLIAPRLPPFDVPDGHTEDSWLRSLVMAGARERYGPPKSAPRAYSQIEHELKVIAQLRFPGYFLVVHDITRFCRDNDILCQGRGSAANSAVCYALGVTAVDPVANELLFERFLSPARDGPPDIDIDIESDQREKVIQYVYHKYGRDYAAQVANVITYRGRSAVRDMARALGFSPGQQDAWSKQVSHWTGQADDVDGIPEQVIDLATQIRNLPRHLGIHSGGMVICDRPIADVCPVEWARMANRSVLQWDKDDCAAIGLVKFDLLGLGMLSALHYAKDLVAEHKGIEVDLARLDLSEPAVYEMLARADSVGVFQVESRAQMATLPRLKPRVFYDLVVEVALIRPGPIQGGSVHPYIRRRNGVDPVIYEHPSMAPALRKTLGVPLFQEQLMQLAVDCAGFSAAEADQLRRAMGSKRSTERMRRLRGRFYDGMRALHGAPDEVIDRIYEKLEAFANFGFPESHALSFASLVFYSAWFKLHHPAAFCAALLRAQPMGFYSPQSLVADARRHGVAVHGPCVNASLAHATCENAGTEVRLGLGAVRYLGAELAEKLVAERTANGPFTSLPDLTSRVQLSVPQVEALATAGALGCFGMSRREALWAAGAAATGRPDRLPGVGSSSHIPALPGMSELELAAADVWATGVSPDSYPTQFLRADLDAMGVLPAERLGSVSDGDRVLIAGAVTHRQRPATAQGVTFINLEDETGMVNVLCTPGVWARHRKLAHTAPALLIRGQVQNASGAITVVAERMGRLTLAVGARSRDFR
The following text describes a protein:
Function:
Acts as a transcriptional repressor.
Sequence:
MYAFVRFLEDNVCYALPVSCVRDFSPRSRLDFDNQKVYAVYRGPEELGAGPESPLRAPRDWGALLLHKAQILALAEDKSDLENSVMQKKIKIPKLSLNHVEEDGEVKDYGEEDLQLRHIKRPEGRKPSEVAHKSIEAVVARLEKQNGLSLGHSTCPEEVFVEASPGTEDMDSLEDAVVPRALYEELLRNYQQQQEEMRHLQQELERTRRQLVQQAKKLKEYGALVSEMKELRDLNRRLQDVLLLRLGSGPAIDLEKVKSECLEPEPELRSTFSEEANTSSYYPAPAPVMDKYILDNGKVHLGSGIWVDEEKWHQLQVTQGDSKYTKNLAVMIWGTDVLKNRSVTGVATKKKKDAVPKPPLSPHKLSIVRECLYDRIAQETVDETEIAQRLSKVNKYICEKIMDINKSCKNEERREAKYNLQ
The following text describes a protein:
Function:
Transcriptional regulator of leaf development. Acts as an adapter-like transcriptional repressor recruiting TPL/TPR corepressors to inhibit the CIN-like TCP transcription factors.
Miscellaneous:
MISCELLANEOUS: Knock down expression of SPEAR2/TIE4 and SPEAR4/TIE3 by RNAi in a SPEAR3/TIE1 null mutant produces lines displaying epinastic leaves.
Subcellular Localization:
Nucleus.
Domain:
Contains 1 EAR motif required for the interaction with TPL and TPRs.
Sequence:
MGSSFFGRPKMGGSSSSSPTSSSSSPAKRGKNKNGSDKPKQPQRGLGVAQLEKIRLHGEYNCNSFNTYPSYHPSTYQEDVRIQGGYPSIPSSSPSFSYASSSPPPAPYGFHPNMMMNANNDQYERTTIRYGDSQPHRAPSWNPSYGILESQHFVEPNTTRHFLHEDQRNISLGSGIQNFETSEANELDLELRL
The following text describes a protein:
Function:
Symporter that selectively cotransports sodium ions and amino acids, such as L-glutamine and L-asparagine from the lysosome into the cytoplasm and may participates in mTORC1 activation. The transport activity requires an acidic lysosomal lumen.
Subcellular Localization:
Cell projection, axon. Lysosome membrane; Multi-pass membrane protein.
Sequence:
MAQAAGSINTDYRDWEWSADAGERARLLQSPSVEAVPKSGESQGNGAGATSALGAVFIVVNAALGAGLLNFPAAFNMAGGVAAGIALQMCMLIFIIGGLVILAYCSQASNERTYQEVVWAVCGKVPGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAALVTEPEEAGSSHWYTDRKFTISITAFLLILPLSIPKEIGFQKYASSLSVIGTWYVTAVIIIKYIWPDKELVPVEIPTSPSTWMAVFNAMPTICFGFQCHVSSVPVFNSMKQPEVKTWGAVVTAAMVIALFVYTGTGVCGFLTFGASVDQDVLLSYPSNDIPVALARAFIILCVLTSYPILHFCGRAVLEGLWLRYTGVTVEEDVVRERRRRLLQTISWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGTPWDAPWALPDSSQTLRDPRNQSSQLVGPGRLRGIHGHPWSLHLRTDHCQRHLRGSCSLTPPPGRTLLLLRGSRFPIRLRGSGEKTF
The following text describes a protein:
Function:
May bind and inhibit the beta-glucanase activity of host plant thaumatin-like proteins.
Subcellular Localization:
Spore wall. Secreted.
Sequence:
MQFTTIASLFAAAGLAAAAPLESRQDTASCPVTTEGDYVWKISEFYGRKPEGTYYNSLGFNIKATNGGTLDFTCSAQADKLEDHKWYSCGENSFMDFSFDSDRSGLLLKQKVSDDITYVATATLPNYCRAGGNGPKDFVCQGVADAYITLVTLPKSS
The following text describes a protein:
Function:
Transcriptional repressor.
Subcellular Localization:
Nucleus.
Sequence:
MAAKMEITLSSNTEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGPQEALSQLRQLCRQWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTLVEDFHRASKKPKQWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPAEPSQAGAYDRLSPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSKGNGLQNPEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVEYISSPLKSHPLRELKKSKGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPYTCGECGNCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
The following text describes a protein:
Function:
Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
Subcellular Localization:
Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Sequence:
MYLFYTKGNGAPTAVPCIGPDELPPPYQQSTNTGGVPMVTCRVCQHMIDITTKREQHVVKCTHCNEATPIRNAPAGKKYVRCPCNCLLICKSSSQRIACPRPNCKRIINLAPSPVTPPVPTMPGMCRVTCGHCSDTFLFNTYHNALARCPHCRKVSSVGSRFANSRAVMFAIVALVFLITGIAVTIGTYSIASDHGGMYFLYVALFVISGCMLARSAYYFRLKVSAIDGPM
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
Subcellular Localization:
Cytoplasm.
Sequence:
MSNFIVGLTGGIASGKSALAAEFEKLGVPVVDADVVARQVVAPGLILDAITNRFGQGILLPDGTLDRQALRKIVFADPTERRALEAITHPAIRTELQRAAKAANHPYAIVAIPLLAEAGARATYPWLDRILVVDVPVALQHARLMQRDGSTSALAGQMIAAQASRAQRLAIADDVVSNEGNTDQLAQQAQRLDATYRAALQTHRIEN
The following text describes a protein:
Function:
Functions as an intracellular glutamine sensor that directly activates the TORC1 signaling pathway, to promote cell growth when glutamine is available. May play a role in repressing NPR1 activity independently of TORC1 signaling.
Subcellular Localization:
Vacuole membrane; Peripheral membrane protein.
Domain:
The FYVE-type zinc finger domain contributes to vacuolar localization.
Sequence:
MTALHSVSKTPAIKEEEEDGDERDGRGVPLGPRNHDYRGRKGDEESGADTVTSPITFEKKKIAPRASTHSEQSILSSISLKSMVNQHRQQQLQQESSTGAGTGFVDRKQQIQSPAMVSILRKNSAEENVRSSHSSKLGEGQIDGRKASASKEIGKTLPFTDDQRSNPELDPTNSVVDVSRGKNTKSKTVFNELEDDADDDDEVRQKNLTTQALRKLSSFKMNASSNLRLSKENKAKESSSSSTSSVSSSSTSKVENIVDKLTTTNSSSMSQLRFGNTNVIIDSVNHAAKPPHQQMLRKPSLEFLPQPASSTNLNFNSNKHKSNVRQISNPKKPLYIPAVLRKVSETNITNDDLLNATLSSYYKKASNLEHGFNPSKSQSASVQNANNLRIISSQSSVQSNTSSILESYKNKISSYLFPNSIPNSDRINLIPTISNRNSARVNPPTKDHWIPDSKRNSCRYCHKPFTLWERKHHCRHCGDIFCQDHLRHWLYLDSQANFIMINELNNGGINGGGTLCKICDDCLVEYENLSTTNHNANTNEDNINVEEGEDDDNDNRKKLRNYYKNRQMNALFRPKKGGSSQEHATVDRDTTTPIQVKSNDEEADNENTGGEQEEGNDVLGSVIGSVPANWNWSSF