lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in a F420-dependent anti-oxidant mechanism that protects M.tuberculosis against oxidative stress and bactericidal agents. Catalyzes the F420H(2)-dependent two-electron reduction of quinones to dihydroquinones, thereby preventing the formation of cytotoxic semiquinones obtained by the one-electron reduction pathway. Since menaquinone is the sole quinone electron carrier in the respiratory chain in M.tuberculosis, the physiological electron acceptor for Fqr-mediated F420H(2) oxidation is therefore likely to be the endogenous menaquinone found in the membrane fraction of M.tuberculosis.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MRLGAGFRKPVPTLLLEHRSRKSGKNFVAPLLYITDRNNVIVVASALGQAENPQWYRNLPPNPDTHIQIGSDRRPVRAVVASSDERARLWPRPVDAYADFDSCQSWTERGIPVIILRPR
The following text describes a protein:
Function:
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
Subcellular Localization:
Peroxisome membrane.
Sequence:
MSLLLSGVVDDGKSKPEVEHTHSEREKRVSNAVEFLLDSRVRRTPTSSKVHFLKSKGLSAEEICEAFTKVGQPKTLNEIKRILSERPYVPTGPNSQHMTQPLRDESADSVPTPHPNQSRRHTSLLYAPQAPPLPEAAAATRGVDWRDLVIGAGAAVIGGFAAFKAFQLYSPYEIRLKDEGSKPRSRRSRRGGRHASSDSEAERSLVHREVPALPVPAIPVASESHVDAKQAEIERLKTELKETQEALEAEKKGKAELSITLGKLRGQVTAYSRTNEKQESQIKSLQEEVNRLKSEIERKEDSAKVNANSNVEETLDSKEEGLPSSDTESSNPNGASSEVARDTQQQDGPAPLSTETDGTVVGGEAA
The following text describes a protein:
Function:
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSTTSVVKLMPHEYLHVEDTNTCEVLTLVGPITYTLYDHHRQLHETPQPCVVVPPSRCVTVKNPMHAVPASLKDKADAPLVYTLLRSSPGSITGLAALPYSRWKVPYGSSELRFCDESPFPLLPGETVDEPSPMPLLTASEALTLEALAPHDVVDPVKGATVHRVAQECFLFKGPGLYTPRLDERIVSKVTGVYVSPPQVCYLSAKYDFVDDDGVPRVAGEQWVVQAHGIFFAHPAVTLQMRDAYVLASFEALTFVSYKAFYDEELQVAREAQKPYLISYADTKDGTYLPRPHETFRGRRRQVHLSATQYCVVINPIGAEGTARLHQAEVRVGKQSFMLQPGEYCTKPLTALVLSEDEALLHVALQTYTEADGTVREGGSRWLVHGPRQYIPPVYARVVERRRIIKVDENCGVYVRNIHTGKVRSAFGKPFMLGADEQLWERPISAYVRRLLAEPRQSLRVTDMSAKERAESSLEEGWAATRAEWDMQASSTAAAEVAGGGCYSASSSGESLDSDDDFMDRDECADELQLLDAATRNAHPPRLSRHISRYHVITANVEHNTLVRLYDTSTGLSRVVAGPATVFLEPHEHFTPLSLSGGRPKEPQQIHSLSLYLGPDYMADIIEVETRDHARLRLHLAYNWEFGSVASNGKAGRVDPELAFTIPDFIGEACKALASRVRSAIAGQAFEFFHCNSSTLIRQAIFTPAEDGSIVSHGDSLCFTANGLYITTVDVQSVEPVNIKTRTALAKSVQLAVEIITKAQESDASHQAALLEQEAKGALDLQVMHDRAKAEQQRTELLRVMGENTALEQAGASRAQALAESAARLAEAQGEVDATPIRCAAHSVGMDTELEVLRKRAVLDLAHRQSLNNLAIDKIRKLSDIEATKYEQIMASLGSETLIAIANAGPELKAKLLGELGLQGFVVTDGKTPINILNMADKMAVGPSATTTPSPAAPGAARVP
The following text describes a protein:
Function:
Membrane-anchored forms may play a role in cellular adhesion.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Secreted.
Sequence:
MPPLQLGFLLMLSWLGADAAPAGTYLCSSLALNETAACTSVRSLSSCCPTCSLRDRFVCYLSPSAVSNMSGDDALSLAQRINESCTLNTTLGRTKGKGAPSSLTTEELQVVSSLVRNFERFTPAVLRVLDQIAVGLSVSDIENKISGEDLEASIPILGKVRGWNADQSSAIINKLLSSGYQISSGQRLAKLGSLVAGLNSSTLRSLPPEVILEAIKLHEFVQQIEVLPSPLKRIFVEKISSSVANPSDLVKLIPAALASYIPKSLLIFEGEKLSVEDLNSKMWTREQAAMFFRDVIKTEPDFSRLSQSVLQGYTCAVANEMDPERVQELATVMKRKNVKLGADQLSCLVKMVTLRGVPKDLDSYPKDLLLFLSPSDYAATGSCKQYFANVGKANLDLLQRESSERKRLLLEALACLKIPGTQVNKENAKILGHLVCDLGEEYIRSSAGTLLKELSQCESFLPGQEEAIRSVISSGNTVFGPPQVWSASTLNELTGLIPVFDHSIWQKVPKDVLTLWLKNFAHDSPLSRAQLATIVAELLPSRQKRDVGCSDAKKITETVLNDEMMPIYYSPEELRACLKNVSLKDYFPQILTYPFTKEQLAVVKEKLDETYPDGYPESLLPRLGPLASLITAEDVSKWKITSADMLAALLQLDLQNEQAAAVISRYVALGNPLNATALNAIDTKYLCILNATLLNMIDPNSLKLASLHPSACSQLTKDILYVKAKRAFSDQHYLRSYYTLIEPYLGGAPVEDLRALSKDNVNMNVDTLVNLRRDALMSLTPAEVKDLLGINLRDLSNWRNTPPIQEWARRQKQTELDKLGVGFTGGTQEGYMNIVTPKFQPPSSAPLGTVATMLHLLPALLLSFLMMSVLS
The following text describes a protein:
Function:
Transcriptional regulator.
Sequence:
MGETIRFGVSIDEKLLESFDGLIEEKGYMNRSEAIRDLIRAALVELKWEVGDEETVGTVTLVYDHHVRDLSDKLTEQQHAHHDKVISALHVHLDAHNCLEVLVVRGKAREVKKIADELIGVKGVKHGKLVMTTTGEELH
The following text describes a protein:
Function:
Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto a terminal alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid of an acceptor, such as N-linked oligosaccharides of glycoproteins and glycolipids through alpha-2,8-linkages. Forms oligosialic and polysialic acid on various sialylated N-acetyllactosamine oligosaccharides of glycoproteins, including FETUB N-glycans, a2-HS-glycoprotein (AHSG) and alpha 2,3-sialylated glycosphingolipids, such as alpha 2,3-sialylparagloboside and ganglioside GM3 and to a lesser extent NCAM1 N-glycans. However, it is much more specific to N-linked oligosaccharides of glycoproteins than glycosphingolipids (By similarity). 2,3-sialylparagloboside serves as the best acceptor substrate among the glycolipids (By similarity). alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-6S-D-GlcNAc and monosialyl and disialyl N-acetyllactosamines are the best acceptor substrates among glycoproteins. May plays critical role in the striatum by mediating the formation of disialylated and trisialylated terminal glycotopes on N- and O-glycans of specific striatal proteins, regulating their distribution in lipid rafts, affecting their interaction with other binding partners, and subsequently modulating striatal functions (By similarity).
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MRNCKMARVASVLGLVMLSVALLILSLISYVSLKKENIFTTPKYASPGAPRMYMFHAGFRSQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA
The following text describes a protein:
Function:
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
Subcellular Localization:
Cytoplasm.
Sequence:
MALIDSNPIPNVTLEAPLYTCGQTTPPTLPVHDFFGEKPYPVGRLLWSADPQSSDFVPADNEHIRKCMRRAAEIHRQVRTYARSVLKVGVSMYAAAEDIESRIRLLCGHSEDEFCTYKPDDNAWCAQAFPLGLSYNHCAAHYTPIKHDDHIIAEKDVIKVDFGIHCDGYIIDSAFTIHFDPMFDPLAQASLEATTEAIKLAGPDVLISELGNKIEEIICSYEMDYKNQNAPIKLQPVRNLSGHMVGKYKIHSGKSIPNCRGKGKEYGRMLEGETFACETFASTGRGMISDEYPVSHYMVSSKSMSLQPAFIKGPEMSKKLFTKLRTMFGTLAWSPRTLESMGEKNFQLALDTLVKNGVVNAYPKLSDKSGCHTSQFEHTFMVGSWGTEVFSAGDDY
The following text describes a protein:
Function:
Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. May play a role in clathrin-mediated endocytosis and intracellular trafficking, and in the dynamics of clathrin assembly/disassembly.
Subcellular Localization:
Cell junction, focal adhesion. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Golgi apparatus, trans-Golgi network.
Sequence:
MSDLFKSAYEYFSGPTNGQSDNNFVGQVIEISNVKLRIKKVIAEGGFAVVFVAQDVATGKDYALKRLLAADEEAKNNIMQEINILKKLAGHPNIIQYLSASFIDKSQTTHGKAEFLLVTELCTGGSLAEILQARSAPFEPEIITRIFYQTCRALAHMHSQNPPIIHRDLKLENLLISRDGTIKLCDFGSATVEIFRPDLTWSANQHDSLEENMAHCTTPMYRAPEMVDTWNNYFVGPPVDIWALGCLLYVFCYMKHPFEDSAKLRIINANYNLPPDPKYSCFQDIIRGCLQVNPEQRLTVSGVLERVAAIAESNGFNLRAPLQFQQKQSPEPDHSSGDGVHNNVKPPPRPVPPKPQPAPERPPQPPQRPAMPVQRPPEGKQSGLFSSLKGGAGSFLKNLKDTSSKVMATMQQSIARTDLDVSYVTSRILVMPYPSEGIESAYKTNHIEDVRVFLDSRHPNLKYSVYNLSGKSYHSKFGQARVVDCTFAYPEHFKAPLLNSLYQLCEDIYQYLAGDSRNVVVVHCTDGKATSATLVCGLLIYSFLYEVPEDALQMFAVKRCPPNMRPSELRYLYYLADIVKNPPAYPHYKPVTFVSIQMQPVPLFTKIRDGCRPYLEVYSENRCLLSTLQDYEKMRLYNVTEGKVLLPINVSVCGDVCITIYHARNILGGVMTQGKATGIKICQLQLHTGFIPEEETCLKFNKSELDEISDGQDHYQDRFMVLLNVFVSDSERKPSQPPPWLTDKTQRVCDTMFSSKLEQDETIDNFASKQPKRVQVSPQKPSERPNRPAPPSPRPAHVELEQKDSSDSEAEQVKPTPKPVEPPLIEAVDLLNLNTTPNPSTIKPSASSNFDLLSGLDSSNDNFPSFPSNPAPNPQPSLFDPFGSSDPQNNLLGDWGNFNSAPPTKPPEPQPQKPTDFFSDLGNLGGGAWNSNASSPIKVPPTTPQQGGTPQHKPVTPQHQAKSPDYSRSHFDAFGDKGEKGKPKSDDVFGDLLGSQGYKFSAKKDNAPRTINDMRKEDMATYMDPDKIKIMEWKEGKKNNIRALLCSLHTVLWEGTKWNKCDMSQLVTPADVKKAYRKACLAVHPDKQTGTDNENMAKLIFMELNNAWSDFENDASQQNIFTS
The following text describes a protein:
Function:
Required for normal spermatogenesis. It functions as a scaffold protein that attaches the sperm head-tail connecting piece to the nuclear envelope, thus maintaining sperm head and tail integrity. May also be involved in the general organization of cellular cytoskeleton (By similarity).
Subcellular Localization:
Cell projection, cilium, flagellum. Note=Localized at the sperm head-tail connecting piece. During spermatogenesis, it is first observed in the cytoplasm of round spermatids, it later appears in the implantation fossa region of the sperm nucleus during sperm head elongation and differentiation, and finally it localizes to the head-tail connecting piece (By similarity).
Sequence:
MKDEAGERDREVSSLNSKLLSLQLDIKNLHDVCKRQRKTLQDNQLCMEEAMNSSHDKKQAQALAFEESEVEFGSSKQCHLRQLQQLKKKLLVLQQELEFHTEELQTSYYSLRQYQSILEKQTSDLVLLHHHCKLKEDEVILYEEEMGNHNENTGEKLHLAQEQLALAGDKIASLERSLNLYRDKYQSSLSNIELLECQVKMLQGELGGIMGQEPENKGDHSKVRIYTSPCMIQEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHRYPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLPQWSVPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGEKDHLHSVMVHLQQENKKLKKEIEEKKMKAENTRLCTKALGPSRTESTQREKVCGTLGWKGLPQDMGQRMDLTKYIGMPHCPGSSYC
The following text describes a protein:
Function:
Promotes efficient viral DNA replication. Recruits the DNA polymerase processivity factor to pre-replication foci.
Miscellaneous:
MISCELLANEOUS: [Isoform p43]: Most abundant product which level of expression remains constant throughout infection.
Subcellular Localization:
Host nucleus. Virion. Note=Found in subnuclear structures known as promyelocytic leukemia oncogenic domains (PODs) or nuclear domain 10 (ND10) during the early stages of viral infection; [p20]: Virion; [p26]: Virion; [p28]: Virion.
Sequence:
MDLPTTVVRKYWTFANPNRILHQSVNQTFDVRQFVFDTARLVNCVDGDGKVLHLNKGWLCATIMQHGEASAGAKTQQGFMSIDITGDGELQEHLFVRGGIVFNKSVSSVVGSSGPNESALLTMISENGNLQVTYVRHYLKNHGESSSGGGGCGAASTASAVCVSSLGGSGGTRDGPSAEEQQRRRQEQRHEERRKKSSSSAGGGGGGGAGGGGGGGGSGGQHSSDSANGLLRDPRLMNRQKERRPPPSSENDGSPPLREAKRQKTTAQHEGHGGGGKNETEQQSGGAGGGGGGGSGRMSLPLDTSEAVAFLNYSSSSSAVSSSSNNHHHHHHHHNAVTDVAAGTDGALLLPIERGAVVSSPSSTSPSSLLSLPRPSSAHSAGETVQESEAAATAAAAGLMMMRRMRRAPAEAAEAPPQSEEENDSTTPVSNCRVPPNSQESAAPQPPRSPRFDDIIQSLTKMLNDCKEKRLCDLPLVSSRLLPETSGGTVVVNHSSVARTAAAVSAAGVGPPAAACPPLVTTGVVPSGSVAGVAPVAAAIETPAAPPRPVCEIKPYVVNPVVATAAAASNSSSSSSAPLPPPPPPSGGRRGRARNNTRGGGGGGGGRNSRRQAASSSSSSSRRSRRRNNRHEDEEDNDPLLRLSQVAGNGRRRGPSFLEDGLEIIDPSEEAAIAAASIAAFFDD
The following text describes a protein:
Function:
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
Subcellular Localization:
Nucleus. Secreted, extracellular space, apoplast.
Sequence:
MQAPQMGPYTGTMITTELIQKYLDENKQLILAILDNQNLGKLHECAAYQSKLQQNLMYLAAIADAQPQNPLPGAQSFFLLALFFLLCIPCYVIKADSRKAQQRQQQFQQQQRLVTAAASAGMLLQPPHSELELGGAGNVSNGNNMTGMGGAFPDYAGNAANGDLMRNSAAAAVSGDASKGTSAVAGSSGATAADAATAANSLQLQRKISFFVRRNWENNPPPSSSPLSSGMGIVRVIDSPIHGTRSNSSECIGRLQGYSITDAAGSSTLFYLTSSFNGSTIKGNLIYQGRASSSARTPEVSVTGTSGVFRFAKGYSLLYMDSQGMPESVESYLYKTL
The following text describes a protein:
Function:
May be involved in 20S pre-rRNA processing.
Sequence:
MLSFQSCVASIVDCWSSFNISLSNGCAGSHAAAKKAWLPGAVIQWLMENNCSDAYELEDTLSSILFNEFHLLVEDGTLSLVCSQIIDALTLCESGRASEAVEKYCNKSNRPVANPPVTIQQDDDDDDDDEEVSNGQDEDVVMVIMDTTAPDSSTSAEHHHQPQPEQQQLQQPQHPQSSQQQQPQQPREQRRNLYNQPDQDGWTTVSKQHKKK
The following text describes a protein:
Function:
Involved in the regulation of pedicel length and of CLAVATA pathways controlling stem cell identity at shoot and flower meristems.
Subcellular Localization:
Nucleus.
Domain:
The N-terminal domain (1-233) has a regulatory function and inhibits phosphatase activity; The conserved PP2C phosphatase domain (271-833) is interrupted by an insertion of approximately 200 amino acids.
Sequence:
MGNGTSRVVGCFVPSNDKNGVDLEFLEPLDEGLGHSFCYVRPSIFESPDITPSNSERFTIDSSTIDSETLTGSFRNDIVDDPSFLNRHNSKGLAETTFKAISGASVSANVSTARTGNQMALCSSDVLEPAASFESTSSFASIPLQPLPRGGSGPLNGFMSGPLERGFASGPLDRNNGFMSGPIEKGVMSGPLDVSDRSNFSAPLSFRRKKPRFQRFMRSVSGPMKSTLARTFSRRSGGLSWMHRFFLHPETRVSWAVGKDGKLHGEDPESCLESNRNLQWAHGKAGEDRVHVVLSEEQGWLFIGIYDGFSGPDAPDFVMSHLYKAIDKELEGLLWDYEEPSEDNQLQPDQEPPTEENMCDPESISEQHSKSVVAESEEVMIDDISSLGNTDTQIADGPPGDSAGPGKKSMRLYELLQLEQWEGEEIGLKRYGGNVALNNMTNQVENPSTSGGGAGNDPCTTDRSALDGIPNSGQRHGTKKSQISSKIRRMYQKQKSLRKKLFPWSYDWHREEGICVEEKIVESSGPIRRRWSGTVDHDAVLRAMARALESTEEAYMDMVEKSLDINPELALMGSCVLVMLMKDQDVYVMNVGDSRAILAQERLHDRHSNPGFGNDEGIGHKSRSRESLVRIELDRISEESPIHNQATPISVSNKNRDVTSYRLKMRAVQLSSDHSTSVEEEIWRIRSEHPEDDQSILKDRVKGQLKVTRAFGAGFLKKPNFNEALLEMFQVEYIGTDPYITCEPCTVHHRLTSSDRFMVLSSDGLYEYFSNEEVVAHVTWFIENVPEGDPAQYLIAELLSRAATKNGMEFHDLLDIPQGDRRKYHDDVSVMVVSLEGRIWRSSGQYYPERKQKFNR
The following text describes a protein:
Function:
Plays a role in the inhibition of host innate immune system by targeting the CGAS enzymatic activity which is the principal cytosolic DNA sensor that detects invading viral DNA. Acts by inhibiting CGAS-DNA phase separation: directly binds double-stranded DNA (dsDNA) in a length dependent but sequence independent manner and is able to form DNA-induced phase separation in infected cells. DNA phase separation of ORF52 mediates disruption of liquid-like droplets in which CGAS is activated, thereby preventing CGAS activity. Targets also the HDP-RNP complex composed of DNA-PK subunits and paraspeckle proteins. This complex is a key nuclear regulator of DNA-mediated activation of innate immune response through the cGAS-STING pathway.
Subcellular Localization:
Host cytoplasm. Virion tegument.
Sequence:
MAAPRGRPKKDLTMEDLTAKISQLTVENRELRKALGSTADPRDRPLTATEKEAQLTATVGALSAAAAKKIEARVRTIFSKVVTQKQVDDALKGLSLRIDVCMSDGGTAKPPPGANNRRRRGASTTRAGVDD
The following text describes a protein:
Function:
Required for arbuscular mycorrhiza (AM) development during AM symbiosis with AM fungi (e.g. Glomeromycota intraradices).
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MKRNPIFLILTFYSLFLLGELKSSLATQPKNENQVYIVYMGGVDSTNGSLRKDHDHVLNMVLRRNEKALVHNYKYGFSGFAARLSKNEANSIAQQPGVVSVFLDPILKLHTTRSWDFLNSQTYVEIDNTLSSSTPSSSDICIPTGWNGTCMTSKDFNSSNCNRKIIGARYYPNLDGGDDNDVAGTPRDMHGHGTHTASTAAGNVVSGASYFGLAAGTAKGGSPGSRLSIYKVCNFGCSGSAILAAFDDAISDGVDILSVSLGGSPDPQPDLKTDVIAIGAFHAVERGIVVICSAGNSGPEQSTVVNDAPWILTVAATTIDRDFQSNVVLGNNKVVKGQAINFSPLSKSPNYPLITGESAKKKTADLTEARQCSPSSLDKKKVKGKIVICDAINDIYPTFSKIETVQKAGGLGLVHISDQDGAVVNNYAKFPATVVRPKDNSILIQYINSTSNPMGTILPTVTIIKYKPAPMVAIFSSRGPSSLSKNILKPDIAAPGVNIVAAGTSSPYSMKTGTSMSCPHVSGLAGSIKSRNPTWSASAIRSAIMTSATQINNMKGPIATDLGLIATPYDYGAGGITTTEPLQPGLVYETSTIDYLNFLCYIGYNTTTIKVISKTVPDSFNCPKDSTRDHISNINYPSIAISNFGGKGSVNVSRIVTNVGEEEEIVYSAVVNAPSGVKVQLIPEKLQFTKRSKKQSYQVIFSSNLTSLKEDLFGFITWRSGKYSVRSPFVLTV
The following text describes a protein:
Function:
Has aminomutase and, to a much lesser extent, ammonia-lyase activity. Primarily, catalyzes the rearrangement of L-tyrosine to S-beta-tyrosine, which is probably incorporated into secondary metabolite myxovalargin. The aminomutase activity exclusively produces S-beta-tyrosine.
Sequence:
MDIYAVAVGRVGVELDAAQLERVRATHLRVQGWGMEKYPMYGVNTGFGELINVIIPPQFKSDLQHNLLRSHAAGGGEPFPDEVVRAIMTVRINCLMKGYSGISPEALQLLATMLNRGIHPVIPMQGSLGASGDLAPLSHMALPLIGDGHVRKNGVTRPTMEVFQEEGLTPLKLGFKEGLALVNGTSAMTGAASLALYRARHLLRLSLLASADIVQAMNASTRPFSHTGNAVKNHPGQVVIARLMRDLTEGTGLMRDHQDIMRAISERTSHSNDVEETEIYLQNAYSLRCMPQVLGVVLETLQMCQRFIEEEANSVNDNPVILDTPAETYHGANFHGQYVAMACDYLSIAVAEMGVLAERQLNRLLDPHINKPLPGFLAHAKTGLFCGFEGGQYLATSIASENLDLAAPSSIKSIPSNGQNQDIVSMGLIAARKTLALCENVGTILSVLMAALNQASHFTEAAKYSAPIRSIHEKLGKVAPRYEDERPMSTVIAQVRGVLLQEQGLALAQSLVNLDLTPDLSLEPRA
The following text describes a protein:
Function:
Baseplate protein that is located next to the tail tube (inner baseplate). Involved in sheath assembly. The gp25-(gp6)2-gp7 module is involved in sheath contraction.
Subcellular Localization:
Virion. Note=Present in 6 copies in the baseplate.
Sequence:
MANINKLYSDIDPEMKMDWNKDVSRSLGLRSIKNSLLGIITTRKGSRPFDPEFGCDLSDQLFENMTPLTADTVERNIESAVRNYEPRIDKLAVNVIPVYDDYTLIVEIRFSVIDNPDDIEQIKLQLASSNRV
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of 2-phosphoglycolate.
Sequence:
MIKLVLVDLDGTLTEDRESTRIDLDAIYAIRLLQKSGIKVSLVSGNSYPILRGLYTYLYLDGGFVAENGCIVFYKEKYRMCRQMEQSLVDEFKSLFKLRDTWQNEYRECDFGFVPAKITDEMINWAKERNLYIKSSGYAVHIAYNPAGKRIGVEKLLQLLGLKKEDVAAIGDSSTDIELFQQVGFKVAVGNADDELKDIADYITSNKSGKGVREFVDKLLKGEFDGIK
The following text describes a protein:
Function:
Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Miscellaneous:
MISCELLANEOUS: Present with 1030 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSSEIAYSNTNTNTENENRNTGAGVDVNTNANANANATANATANATANATAELNLPTVDEQRQYKVQLLLHINSILLARVIQMNNSLQNNLQNNINNSNNNNIIRIQQLISQFLKRVHANLQCISQINQGVPSAKPLILTPPQLANQQQPPQDILSKLYLLLARVFEIW
The following text describes a protein:
Function:
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Miscellaneous:
MISCELLANEOUS: Present with 3260 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion intermembrane space.
Sequence:
MAVKGLGKPDQVYDGSKIRVGIIHARWNRVIIDALVKGAIERMASLGVEENNIIIETVPGSYELPWGTKRFVDRQAKLGKPLDVVIPIGVLIKGSTMHFEYISDSTTHALMNLQEKVDMPVIFGLLTCMTEEQALARAGIDEAHSMHNHGEDWGAAAVEMAVKFGKNAF
The following text describes a protein:
Function:
Plays a role in GABAergic and V2 interneurons differentiation. Involved in motoneuron development and in neuromuscular junction formation.
Subcellular Localization:
Nucleus. Cytoplasm. Postsynaptic cell membrane.
Sequence:
MADEQEIMCKLENIKEIRNKTIQMEKIKSRLRTEFEALESEEKHLREYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSESDLNKLLESTRRLHDEYKPLKEHVDALRMTLGLQRLPDLSQEEEKLSLDYFEKQKAEWQTEPQEPPIPESLAAAAAAAQQLQAARKQDARQTATFRQQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKPDE
The following text describes a protein:
Function:
Involved in cell division and chromosome segregation.
Sequence:
MSYSSNVKQEITKKIPATNLECLAEISSIFENKSMSLKDGVEIKMENSILAKRVYSLIKNTSSLKFGIKYSVTKKFTEHKVYTITLYKQKGLKEFLDSFKFSYLDIIQNDEIFRGYIRGFFLSCGYIKDPKKEYSLDFFVDNEELAGKIYNILFSKKKKIFKTNKKNKILVYLRNSEDIMDILVLMDALQHFFEYEETTIIKNLKNKTIREMNWEVANETKTLNTGNYQIKMIKYIGEKIGLNSLSPVLEEAAFLRLNNPEDSLQSLADMINISKSGIRNRFRRIEEIYNSLLEEEKNS
The following text describes a protein:
Function:
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases (By similarity). The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. The MRN complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11, to initiate end resection, which is required for single-strand invasion and recombination. Within the MRN complex, NBS1 acts as a protein-protein adapter, which specifically recognizes and binds phosphorylated proteins, promoting their recruitment to DNA damage sites. Recruits MRE11 and RAD50 components of the MRN complex to DSBs in response to DNA damage (By similarity).
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to DNA double-strand breaks (DSBs).
Domain:
The FHA and BRCT domains are likely to have a crucial role for both binding to histone H2AFX and for relocalization of MRE11/RAD50 complex to the vicinity of DNA damage.
Sequence:
MVWALTPVDTVRGAQRCYIFAAGTYKVGRKDCDVIVQTDTSISRVHAEIVVEKMVAWDPQSGAPANPSYVRVVDRSKYGTFFNKVQGTQGSRLHKDEDAMLADGDTVTFGTGSATFRLSFVPIVVFFHGKKSGRISPSLQAVMTSIGAYATRKWSDECTHVLVDESCSLTPELLDAVLAKKQIVLGDWFKVMAEKNIHTAMPSSTQYIPKLTLDGMEIQVVEIKLIESCLAGYTFILGSSEKYKFGDKLHALLESTGAKYLHVDEFCANSQDSGAGENDKDILLVPAKSPLEFSKISGLFPLSKITDVKLFAAILSGHLEATAIEPPAYIVASSNSTDETIVVDSDVEIDTATSDHTVAASKSEHHIEHISDDKKEVVAISEEDAVNLVEAKTSINLHSYQEKDEIVKPMEEDVKVIEKTATMRGFKVEGEDIPVMTKVPKDETLDSRDETCHVIYTQNLVVKSILQSARAESIETGGINFKRFRKRGAVSGNSFKDLIPYSREPYRESDYKRGTVIDFMREEKKRRQMEAIAEDLFNNAKPKKKAAAGSSIHTMLTGRR
The following text describes a protein:
Function:
Involved in the coordination between cell elongation and cellulose synthesis by promoting the expression of genes involved in cell elongation and cellulose synthesis. Acts as a regulator of plasmodesmatal permeability. Maybe a glycosyltransferase.
Subcellular Localization:
Secreted, cell wall. Cytoplasm. Cell membrane.
Sequence:
MAGLYSSSSSSKPTLSSSPSSSSSSRLFLLVTLLPLSLACFAFVLQWRGGLDDPVTHWSIDHHEFPGMVTTQEKRSLRRSVSDSGCVDLLGQSRSPSFPYFRNWKFDYHSDLKPRICITTSTSAGLEQTLPWIYFHKVIGVSTFYLFVEGKAASPNVSRVLETIPGVKVIYRTKELEEKQAKSRIWNETWLSSFFYKPCNYELFVKQSLNMEMAITMAQDAGMEWIIHLDTDELIHPSGTHEYSLRKLLGNISADVDVVIFPNYESSVERDDIREPFSEVSMFKKNFDHLLRDVYFGNYKDATRGNPNYFLTYGNGKAAARVQDHLRPNGAHRWHNYRKSPNEVKLEEAAVLHYTYPRFSDLTSRRDRCGCKPTKVDVKRCFMLEFDRAAFIIASTASSEEMLQWYREHVVWTDEKLKLKLLRKGILTRIYAPMVIIQELREAGVFSSVVIAAHKSPSKNSSTADSTSGITRESSQETGKRRVLEFHLDVDGESQASAVPPQSPPGLEATQMEL
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Miscellaneous:
MISCELLANEOUS: Present with 3460 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Sequence:
MSYGLTGTSSKLRGTSSIFSWTQVRHFSRRRIAYPFYPFKKLGRQHPKKHDTNLKTAMRQFLGPKNYKGEYVMNKYFTVPTNHVPNYIKPDLERGQSLEHPVTKKPLQLRYDGTLGPPPVENKRLQNIFKDRLLQPFPSNPHCKTNYVLSPQLKQSIFEEITVEGLSAQQVSQKYGLKIPRVEAIVKLVSVENSWNRRNRVSSDLKTMDETLYRMFPVFDSDASFKRENLSEIPVPQKTLASRFLTIAESEPFGPVDAAHVLELEPAVETLRNLSTVGEHSSGHQQSTNKNTKVIYGELVEGERSQYKFTNAKVGKVGYRYGSGNRDNKKDRRIGFNKLGQMVYI