lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSENNPVKYLADSDTECQRCKAVPAVLITRKEAFCKNCFIRFIRGKQRKSMIDERYKVKYGAVQEKIGQQKVLLALSGGVSSLVLTDVVASLLQEQIESHKGRMGFELVLLNIDEFELESLNKRIEEILPILVERYAPVNIQYKVLSIESFLIDRAMIQKVLLNKDFTAIAQRLSDEQNKYTVADMLKLCPNKSSMEDLLTVIYEELILRTAFIENCETIIYGHSMTRIANEILALTVRGRGSSVYKAIADHTVQFMDKEFTILFPLRDVLFAEIIAYADLIELNKLEVKSTIVKSKITKNLTIRDLTTNYFSHLDATGYASTASTVVKTGEKLGAPQFKHSYGRCQICGVEIYQDPKEWLRRITVNDAAPIETEEEQEYVNLYKEALSSSETLDTENTHPVNICYGCIVTLSGAKQDTAFVWPLKDKDTNHEDKKVLDEYILTDDEE
The following text describes a protein:
Function:
G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR4 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Sequence:
MLSKVVLGVILSLLILLTVGGNVLVCLAVCASRRLRCLTNCFIVSLAVTDLLLGLLVLPFSALILISDDWPLGPVFCNFYISMDVMLCTASILTLLAISVDRYLAVTMPLRYGSIVVPWRVGVAMMSVWIVSVALSFLPIQMGWNTVNGTVQNQGPWASERRCRFELNRPYVLTDSLLTFYLPLVAMCWTYLQILRIARVQAKRIINTRPTCVTSYDCRSNPPTSTTLACSVTAVALREHKATVTLAAVIGAFVVCWLPYFILFTVLGLREHPDPAIVPAYPVVLWLGYANSALNPFLYGVLNRDFRAAYTHLLICHFHSYSGCRIKKSSPTTGAAREHLTEMILLCGQTPATCRAAITDQNVMHEGKNSRTATTAIHFANGTAVTDVTGNDRETALQCVFMLHFTYTNGKCCRVCPSGNMKNHNLE
The following text describes a protein:
Function:
Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKGGRQASKPQAQRQGFKRRQAPAAPEYDYEDEGPAGSDEDEDGMTPDQLRALKRFKAGPGGSDDDSDMSDEDEEGEGDSDDGGDGSDGGGRGRGRRLDRLGAARDDDDDDEGGEDEDEDEEDEDEDEEDDDDDDDDDNGGGASGRGNERTLEEQVADVPFEVLEAIKRDGRGLVGQAARVAAARADAASANFKRANKDRPQEMSSKRPVGRFREVIQVPNTKSVDPRFDSSGAPGGGKDTFRRRYAFLYDDMLPAEKAELQAKMKKEKNPKFKAKMQAQLQRLEAQLKDESLRRRTQALEREWKSKEKVAVGSGKQPYFLKAADKKKLELLAKYQELKEGGKLDKFMEKRRKKNAAKDHRYLPSARRADE
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDESTLHIKEEPCEISEFLVEEGQETEAKEENVNEDWGAEAFAGEETEDYPQDKDSCGFICPECGKTFESQFLLSVHQATHMRESHVCPACGQSFVQRSSLVHHQTLHCRGNCQLSTSSSSPALSVPSSYRCGLCHMVLPGPNELRRHLASHKGARRYTCKECNRTFSCNYFLVRHQRTHSGERPFVCPQCNKSFSCSSVLYRHQRLHMGVQPYKCELCVKHFSQKSSLITHMRTHMAERPYSCQLCGKSFSTNSALIRHQQRHQQGKLCTENQENGVSDKDAKWKLPKILLRKAADGFSFTAVGDRKWVEQQMDCGRIQGKLVMEMHVGDDEKLDIKKDYDEVSVQGSFLTRSPVKLENIEENSTGSPQHSSEVPMYQKTHPRDRPFICRGCGKSFGYQSSLIQHCLFHCSCKPMKYMSADVSGSLGQSLYKCGVCSAAFTGRAQLKSHLSSHSGELRYWCKECGRRFNSNYLLVRHQRIHTGDKSFQCQVCERAFSQKTTLVIHLRSHTGERPYLCQVCGKGFCSRSALVRHHHSEKDKERGGQQNNSKASRRRKEVRKPRGGAKRKKLSMDTESMRKVVIHDEDFEIIHTPAPKGSGRSSVACADCGKTFKSQTHLTIHSRMHTGERPFSCACGKSFGHRSTLIRHRNFHCNVKSDMVIPTHAATPTQRIYKCGICHSNFPSTGELKKHLSSHTGEQRYTCTDCGRTFNGNFYLVRHQRTHTGERPFVCHRCNKSFKCSSVLYRHQRTHYGEMPFKCEACGKGFSQKTSLIIHQRTHTGERPYLCHICDRSFCSSAALSRHEHSHLLDGIASVQSVVDQHPEEADFADGSVGEEAGEVGDTSKDGEFWEGSDRSLDSLKDKSSEADFRNGAEGSWADPAPAMEKSNNDLQIEVGENKAGGFICPKCGKFFTSQSLLRQHQRAHSAAPSHFMCPHCGKAFSQSSSLERHMSSYCKMRPVLEPSEAIDFIPAVQPMNKCGICDVTFPSRNELRKHLAGHTGNEPYTCKDCGRTFSCNYFLVRHQRAHTGERPFVCPQCNKSFRCSSVLYRHQRSHSGELPFKCEVCDKGFGQKNTLIIHLRTHTGERPYPCPHCARCFRCSSALARHEQTHKKNIDVKDID
The following text describes a protein:
Function:
Nonselective cationic channel with high permeability to Ca(2+). Component of a mechanosensitive cation channel. Confers mechanically activated (MA) currents with slow inactivation kinetics. May contribute to proprioception.
Miscellaneous:
MISCELLANEOUS: Tentonin comes from the Greek 'tentono' meaning to stretch.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note=Localizes at the plasma membrane. A portion co-localizes with LAMP1 lysosomal marker.
Sequence:
MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAARKSGVKHAPYISFAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNISGLVALCLASFGMTLLGNFQLTNDEEIHNVGTSLTFGFGTLTCWIQAALTLKVNIKNEGRRAGIPRVILSAVITLCVVLYFILMAQDIHMYAARVQWGLVMCFLAYFGTLAVEFRHYRYEIVCSEYQENFLSFSESLSEASEYQTDQV
The following text describes a protein:
Function:
Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MDLSKALNQECFDQTALDQAVLEYAVGLQHSLVNYLFQCYERSLTHGDEPEIHDVRKTIFSNLDLAFSQPELFPEQNLHEDFLQLLAFSSEDTSKFLDSFVQHLLAPENPASVTEVFLPLFASLNTKLTNMHLLMGNQSELDAMMVLSKQPTLAKDMVSTSILNENIIGRVGKQCEQTLLGSLFLCSCIPRVPGTPSDFFDRPSRSPPGVHATTEGNIWSASERIMDKVYKIFYNLFKSSPEVQNLTRKWLGQVLELNKARGQMWAQHDMTAQVHCVSDGFMTNLGAVLLQLCRPFCSIDDPKSCDRLSKIDATFCSAKETKDNGVHIADLHKETCLITQENRPAAKSLPYSFSTELFYMTHRALELGAKAVHSQMLQMSQNFNRLQRAYQDAEQSGQTPVAQQIQERMDVMMSSYLCFKAVLLVPEWLKMQFEFIMATSKWLCGTALGVHPSNVTSCDVNKEHSSELLTCIPEFCLSNVMDFVVFVNRFSPGTLDRGQLDDLLTLIVVFMGSPNRLKNPHMRAGMAEMLDGLMPPDRGHAAPPSSRTALFVKHPRANDVVGTLLHVFASIEMTGQGVAFEQKFNYRRPMYAAMKFLWSLKLHQRQFKVLAAEAEANMEAAQPPLFLQFVNLLINDAIYLLDEGLSYMAQLKEQQQQREDGSWPNVPAGPQRHQREATYQHITMLARFHNLMGRETIRILEMMTTEIKGVFVHSTMVDRVASMLNYFLLHLVGPKKRDFKVKDVGDYEFDPAELVSCICQIYCHLSSVDVFCTAVSQDGRSYSPQLFGLAEDVLSRIGRGALIGDLQLVAKKVSELASAKASDEDLISSAPDEFLDPIMSSIMMNPVILPSSRVTVDRSTIARHLLSDQSDPFNRSPLTMEDILPDDELREKIHKWIAEMKKKAVIPPVDERI
The following text describes a protein:
Function:
Transcriptional activator. Common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. With MYC3 and MYC4, controls additively subsets of JA-dependent responses. In cooperation with MYB2 is involved in the regulation of ABA-inducible genes under drought stress conditions. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the MYC recognition site (5'-CACATG-3'), and to the G-box (5'-CACNTG-3') and Z-box (5'-ATACGTGT-3') of promoters. Binds directly to the promoters of the transcription factors PLETHORA1 (PLT1) and PLT2 and represses their expression. Negative regulator of blue light-mediated photomorphogenic growth and blue- and far-red-light regulated gene expression. Activates multiple TIFY/JAZ promoters. Positive regulator of lateral root formation. Regulates sesquiterpene biosynthesis. Subjected to proteasome-dependent proteolysis. The presence of the destruction element (DE) involved in turnover is required for the function to regulate gene transcription.
Subcellular Localization:
Nucleus.
Domain:
The transcriptional activation domain (TAD) (149-188) overlaps with the destruction element (DE) (154-165); The JAZ-interaction domain (JID) (93-160) is sufficient for interaction with MYB proteins and most of the TIFY/JAZ proteins; The C-terminal half contains an active nuclear localization signal (NLS).
Sequence:
MTDYRLQPTMNLWTTDDNASMMEAFMSSSDISTLWPPASTTTTTATTETTPTPAMEIPAQAGFNQETLQQRLQALIEGTHEGWTYAIFWQPSYDFSGASVLGWGDGYYKGEEDKANPRRRSSSPPFSTPADQEYRKKVLRELNSLISGGVAPSDDAVDEEVTDTEWFFLVSMTQSFACGAGLAGKAFATGNAVWVSGSDQLSGSGCERAKQGGVFGMHTIACIPSANGVVEVGSTEPIRQSSDLINKVRILFNFDGGAGDLSGLNWNLDPDQGENDPSMWINDPIGTPGSNEPGNGAPSSSSQLFSKSIQFENGSSSTITENPNLDPTPSPVHSQTQNPKFNNTFSRELNFSTSSSTLVKPRSGEILNFGDEGKRSSGNPDPSSYSGQTQFENKRKRSMVLNEDKVLSFGDKTAGESDHSDLEASVVKEVAVEKRPKKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRAVVPNVSKMDKASLLGDAIAYINELKSKVVKTESEKLQIKNQLEEVKLELAGRKASASGGDMSSSCSSIKPVGMEIEVKIIGWDAMIRVESSKRNHPAARLMSALMDLELEVNHASMSVVNDLMIQQATVKMGFRIYTQEQLRASLISKIG
The following text describes a protein:
Function:
Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Thr-523' and 'Ser-573'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in postmitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation of gamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins to the centrosome. Involved in the UV-induced DNA damage checkpoint response, probably by inhibiting CDK1 activity through phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C (By similarity). In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1.
Miscellaneous:
MISCELLANEOUS: Protein synthesis is inhibited by the TSC1-TSC2 complex acting through TORC1 in neurons, leading to regulate neuron polarization.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Synapse. Presynaptic active zone. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage (By similarity).
Sequence:
MSSGSKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRRPERKSMEVLSITDAGSGGSPVPTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPGVGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSARSTPLPGPPGSPRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAAWRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKDKPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASGGPSVFQKPVRFQVDISSSEGPEPSPRRDGSSGGGIYSVTFTLISGPSRRFKRVVETIQAQLLSTHDQPSVQALADEKNGAQTRPAGTPPRSLQPPPGRPDPDLSSSPRRGPSKDKKLLATNGTPLP
The following text describes a protein:
Function:
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Sequence:
MKIYLFEISKTDLAGRIGTIDTNHGKIETPAYVPVIHPVKQTIPSKKIKEIGFDLVITNAYITRNNYGDKAVKKGIHKIIDYDRGIMTDSGGYQVLEYGDVPVAPTEMAEFEQGIMTDFAIPLDKPTGFGLPIKKAEAYVKHTLKVCKQTIEDSKDNGQIWIGPIQGGEHFDLVAKSTKGLIKMGYKMLALGSPVEFMESYEYRLLAQMIIAAKKQIPHNIPLHLFGAGHPLTIPFAVALGCDTFDSASYMLYAKQNRYITEDGTRDLSDIVVFPCNCEICTKYTPDELRQLESIEKINQIAIHNLHAIKLEVDKVKQAIHEGRLWEYVIKKARAHPKLFEMVEVMTENSEFLKIGTPKFKERAIFLFDKEDQFRPEVQVFHEIVRGFKSKKEKILITNESSTKPGYLSHQFVNLSKKLKDFEEVQICQYNPQLGLIPIEISDIFPAAHHETSRMNFDPKEFTEFEKTWKIFFENNKFSEIRYNKDDEFLKYFVKTLPKNIKKKSFL
The following text describes a protein:
Function:
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the second glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(1)Man(9)GlcNAc(2)-PP-Dol to produce Glc(2)Man(9)GlcNAc(2)-PP-Dol.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSKKSFVKGPSGLPKELNNDKQWNYSLVNIWVASLALKLLLSVGYHSTDFDVHRNWLAITYNLPISKWYIENTSQWTLDYPPFFAYFEWVLASFVPDFVKRDGCLKIVEKGLYSLPTVLFQRLSVIVSEVVLFVSLQWYINSSKTHTEAKRAFVVASSLVLSPGLLIIDHIHFQYNGMLYGILVLMINSARLKKYLMCGFWFSILICFKHIYLYLAPAVFIFLLRAYCLNLNFGKTKSSNILKIVRWKNLFKLSSIVIAVFSIAFGPFIYYEVMPQLIERLFPFNRGLTHAYWAPNVWAIYSAIDRLLIQIYYRIPISRPILLKIFKFNPQYLWDTKLVNKTTRGLIGDVEFLILPTITSQLTFFLTLFYQVMALIPLFLQPTFRRFMGSLTLCGFASFLFGWHVHEKAVLVVIFPMTFLVSRDRDLLGPFNLLVSCAYISLFPLIFTCDEWLIKITYMLLWYIVYYFSLKKVVRLPKTNGGYGKVILDRVNNGYILGLVPVITIVSLIDLFEHKFEILRKLQFMKLLIISVYCGIGIISSWNGFSWLYFVDESIWTDE
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MQRETTLVDELEVSANEVILGEMLSSCSVACADAILANNIAESAIARHSALLRVAVDSNQGSSLERSLRWESVKQAEEEMKVKKEEAKGASERAREELAKMKLMIERSPDAGSVGGSWEGMMEDVEGAVVKVTKREEEESMLEEYRALVEDARVKLDGKLTGLPPVGGDIDILLHNQHRVEQLQQELVELREEHEVALKEVEEKVREEWGGRRREEWEEEERRRREEVRGEWEEKEMMSQLKRQASSHAEHLAQAMSYLERQASERYEKMLTEITTELQREVREAREEHEARTTTIAEDFQSKLNLAQAKVAGIESVVDGRATIEGESRKAQELSLACDGLLFSLKYGEGGLPTPLHKDLESVKKVYNEHPVIEILTSAVPHEAVERGVYTEEMLRSAFSRIGKICRRVSMIDENKDSLLVYFLSYLKSLLTISSAQLQPPTEIDESKLDVFSIISYANYCVQHGDLEQAARFVNQLTGEPRKVVDGWLSEVRLFLETRQTIEALSLVSNSIVIGTQLE
The following text describes a protein:
Function:
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPAWPRFMSLRRQYLYKALDKNHQKHPIKHPHTRFLSRLFCALAVLFSYSIYQSFRTDLKQSGSWGCEMSWMSPSYRRLEWTEFISTRYALYLYREQGLDSEDTLSGHPVLFVPGNAGSYQQVRSIASSASKQYYEQVKARERNVVTGKKIDFFTADLKEEFSAFHARTVREQAVFIQHCIKGILQEYTHLPQEKRPTQVTLLAHSMGGVVARLAMDPITSISVDIIVTLSTPHILPPLALERDMDSIYSLIRWRRQHISTHPPLISICGGISDTQIVSDSCALPFFQAGNNSDIAVFTTGIPGVWTAVEHQAIIWCHQIRWRIARMLLDMSSRANTTAKLVTAKEWLLDYQEDETLKEPRSERQHDYSVSSRNMTFIGLHQPSKAFVAQQCNGLERCRTVPSVMSLLPFPNNPSDPFPLPGEGIKPSEVMLVAEISLSSTNTVVKINASQYGQTIAGSREHHLVKGNSWKVNSSLPSLTTHHLFHFENAFLSSLVTHSLDITLGHCKDFKPLIKHISQPALELQSATFESNYYFASGRPIHLHSHSTAGPFLPYQDRAGIYLEIFQSPLCPVQQVSLRKNYYNVLAKSVTRYRMVVLAWPVGWATVVLLFQLSDFINTGEILPWNSALERIARRRMPICIVLLLLGATIQSQLPDFPMLHTFFLGVNQLEMVPLVGILGVWTFGLLCVVSFVITACLWLLGCIIQQPHGHERLEDETKSKHDWLGVVMIGAAAVLVNQVIPHQLIFLLCVILLWLSAARSKALNDRYHLISTCAIFTTLLIPFKILHVAIWSRNIWTGSAALVSTDNNFYYAIPPVLLVKCASCGGTIQKRHVCLKACRIALIILIMSSFSVGARWTWILSPIANAVLILFVASII
The following text describes a protein:
Function:
N-acetyl-D-glucosamine binding lectin. Shows low hemagglutinating activity towards human erythrocytes. Has low mitogenic activity towards human peripheral blood lymphocytes.
Sequence:
APECGREAHCGDDCQSQVVTRDFDDRTCPKLLCCSKDGWCGNTDANWRCGVDFGRTCPNDLCCS
The following text describes a protein:
Function:
Catalyzes the conversion of L-glutamine and 2-oxoglutarate into two molecules of L-glutamate.
Sequence:
MSLYHPSFERDNCGFGLIAQMDGEASHRIVRTAIHGLDRMKHRGGIASDGRTGDGCGLLMQLPLQFFEAVAAENDWHLSRKFAVGMLFLSQDEELADQAKFILERELERETLSIAGWRKVPVNPDVLGEIGKSSLPQIYQVLINAPIGWREKDLERRLYMARRRLEQQITDDKDFYVASLSGQVIVYKGLMMPADLPAFYPDLADIRLKSSICLFHQRFSTNTSPKWPLAQPFRYLAHNGEINTITGNRQWARARAYKFNSPLLPDLQQAAPFVNETGSDSSSLDNMLEMLLSGGMDLYRAMRLLIPPAWQSNPEMDDELKAFYDFNSMHMEPWDGPAGIVMTNGRHAACAVDRNGLRPSRYVITKDRILTLASEVGIWDYAADEVIEKGRVGPGELLVLDTLNGRLYQSFEIDNDLKRRHPYKEWMAKNSRTLIPAEQLTTEQHGASELSPEQLLQYQKQFGYTREELEQVIWVLAKQGEEATGSMGDDTPMAVLSKKSRSLYDYFRQKFAQVTNPPIDPLREKHVMSLATCIGREQNLFNETTGHAYRVMFNSPILLFSDFNQLLGLDSTYYRANIVDLNYEPKEGLEQAIRRITSEAERLARSGTTLLILSDRAIDKSAQVIPVAMAVGAVQQMLVSKSLRCDTNIIVETASARDPHHFAVLLGFGATAIYPYLVYESISDLAKRHDLTDTTALMLNFRYGIEKGLRKIMSKMGISTIGSYRCSQQFEAIGIASDVIELCFKGVISRIEGASFEDIANDQALLHKAAYRAHVPLPQGGLLKYVDGGEYHCFNPDVVNTLQASLIDKNFATYKKFAELVDNRPIATLRDLIGIKAGQTAIELNNVEAASNLYPRFDSAAMSIGALSPEAHEALAIAMNRLGGRSNSGEGGEDARRFNTERNSAIKQIASARFGVTAHYLVNADVLQIKVAQGAKPGEGGQLPGHKVSVEIAGLRHARPGVTLISPPPHHDIYSIEDLAQLIFDLKQINTKALISVKLVSEPGVGTIATGVAKAYADMITISGYDGGTGASPITSVKYAGSPWELGLAEVHQSLVENGLRHKIRLQVDGGLKTGTDVIKAALLGAESFGFGTVPMIALGCKYLRICHLNNCATGVATQDKKLRDNHYHGLPERVMTYFEFVAEEVREWMATLGVSKFEDLVGRSEWLHTLEGQTDKQRGLDLAPILYQPNVRASTSRTWQETNPPADLGLLNQHLLNECQSAVDKGESFDAAYSINNTDRSVGARLSGYIATTLGVKGSKAPIKLSFNGSAGQSFGVWNSPGLELKLCGDANDYVGKGMSGGKIVIYPPLGSPFQSERSAIVGNTCLYGATGGRFFAAGQAGERFAVRNSGAIAVVEGLGDNGCEYMTSGIVVVLGKTGVNFGAGMTGGFAYVFDQFGRFNRRVNSELVDTQKLESPIQQQHLKGLIEEHVAETGSEHAKMILSDFANWLDCFVLVKPKNIAVADLLKLEQSSPELAVKAG
The following text describes a protein:
Function:
The dimeric enzyme acts as an E1 ligase for smo-1. It mediates ATP-dependent activation of smo-1 and formation of a thioester with a conserved cysteine residue on uba-2 (Probable).
Sequence:
MEVSKAEQAIYDRQIRLWGMEAQNKIRNSKVLIIGGKQLGAEVAKTLSLAGVDEMHLVDHRLVDTEEIGMNFLYDASVDNSKMTKWAASYNFLYNLNRNVKLFIVEEDVLSKNDSEIEEYLTKFTLVVVLDESYERTAKVNNICRKHHIRFISGAIYGWIGYAFFDFDGHAYLVKAKSPDCLNEEESETGKTSTVVTVDEEFVLETFSYPSFVETLNSDFTAKKIVRKCKRIVPTSYFLVKSMLRASSENKLTGVTENDIEKLIPIWNEEVAAGNHTIDMQPVQPDRFDHLFGPNFGPTAACVGGVIGQEAIKSISEGKNPLRNLFIYTGFESTGFMCNFPPV
The following text describes a protein:
Function:
Probably part of the binding-protein-dependent transport system YdhWXYZ for an amino acid.
Subcellular Localization:
Periplasm.
Sequence:
MKKMMIATLAAASVLLAVANQAXAGATLDAVQKKGFVQCGISDGLPGFSYADADGKFSGIDVDICRGVAAAVFGDDTKVKYTPLTAKERFTALQSGEVDLLSRNTTWTSSRDAGMGMAFTGVTYYDGIGFLTHDKAGLKSAKELDGATVCIQAGTDTELNVADYFKANNMKYTPVTFDRSDESAKALESGRCDTLASDQSQLYALRIKLSNPAEWIVLPEVISKEPLGPVVRRGDDEWFSIVRWTLFAMLNAEEMGINSQNVDEKAANPATPDMAHLLGKEGDYGKDLKLDNKWAYNIIKQVGNYSEIFERNVGSESPLKIKRGQNNLWNNGGIQYAPPVR
The following text describes a protein:
Function:
Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.
Sequence:
MQWLTLILVGLFASFLSISMCVAVQPPDDGKLRVCVVESRGVYRKTPKFCPLLEAKSNIECVIGVDRLDCVRRIHKGTAHFGVLTSEDLVAARWASVEILVASELRSHESHFEYEIVAVVDNHANIHTVHDLRGARLCHPGYGLGNHWTEVLANYFEAAMVSKTCDPEMTVTEDRIASTAKYFGPSCKAGPWVPDPKQDRILKNRYPSLCEMCYEPDSCDQTDKHWGRRGALYCLTSGGGNVAWARLDDVRSHFGFSGIPAQSNPSDFSYLCPDGHLQPLNASQPCVWVAKPWPVVAARRSHAAQVQRLVTGLNHDEPDSWQNALLSLLETYHVFTVPLDNVIAIDDYLDQATAFQSAYSFPECNPPRSIVFCTTSIIQHIKCSWLQEASQVYGVQPNIQCVRTMDEQQCLDNTKFKETDVVLVDQEMRVKAQRDYNLVPLLYEFAADMHDRYVTIALVHKDAKFESFRDLKGARACLPSFEGAAHLSVQETIVNATGKVQSLHSYFHRDSCLWNLQSGRKCPLHYQGDEGALRCLSEGADVAFLSSDVYKKYVVGNLTSNWLTPGNHKDFRVLCPYGGIEKRSNFEYCYLHWTTRGHLMTHNSSLTRRNEIYNSLRDMDQLFGRKYKSETRPFTLYGIFDKRNNVLFRDDTDGLLGLQELHRDNAKRVMEHIYDRYANTQYYRNFDESGAMKSSHNLWILLVCLLFVVGQPFG
The following text describes a protein:
Function:
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSTIMKHTVGFIASIVLTLLAVYVTLYTSLTFHAKLTIIFGFAFVQAGLQLLMFMHLTEGKDGRLQTFKVIFALVITLCFVVGTYWVMQGGHSSHL
The following text describes a protein:
Function:
Provides the tetrahydrofolates necessary for the synthesis of nucleotides and amino acids. Bacteriophage T5 induces high levels of dihydrofolate reductase in the host cell, probably for the viral replication.
Sequence:
MITAMYAVGPNGEFGLRGKLPWGSFKEELDAFYSQLDVLNPDNIIIGAGTYLALPYAVRERMIGASDLFIRADRPLPDDITHDIYTPISMIGDTLPTFLKDQQTVVLGGANLLLEMYQHGHIESAFVSTIFSEQKLEADTHLDSMILDYNYESTRLVYAVGANSDNSLRFVQELVTY
The following text describes a protein:
Function:
Glycosyltransferase involved in the O-arabinosylation of several proteins including extensins and small signaling peptides. Catalyzes the transfer of the initial L-arabinose to the hydroxyl group of Hyp residues. Contributes redundantly with HPAT1 and HPAT2 to arabinosylation of EXT3, but main contributor to arabinosylation of CLE peptides.
Subcellular Localization:
Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein.
Sequence:
MGKASGLLLFLLGFGFFVVTYNLLTLIVHNRSGVSNSDGSPLLDPVVQMPLNIRKAKSSPAPFHVALTATDAPYNKWQCRIMYYWYKQKKALPGSDMGGFTRILHSGNSDNLMDEIPTFVVDPLPPGLDRGYVVLNRPWAFVQWLERATIKEDYVLMAEPDHVFVNPLPNLAVGGFPAAFPFFYITPEKYENIVRKYYPAEMGPVTNIDPIGNSPVIISKESLEKIAPTWMNVSLTMKNDPETDKAFGWVLEMYGYAIASAIHGVRHILRKDFMLQPPWDLSTKGKFIIHYTYGCDYNMKGELTYGKIGEWRFDKRSHLRGPPPRNMSLPPPGVPESVVTLVKMVNEATATIPNWDTL
The following text describes a protein:
Function:
Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in skeletal muscle and heart development as well as in the maintenance of heart function. May play a role in vamp3-mediated vesicular transport and recycling of receptor molecules. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. May induce primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. May be involved in epithelial movement during corneal sheet formation and regeneration. May play a role in the regulation of cell shape and movement by modulating the Rho-GTPase activity. May also be involved in striated muscle regeneration and in the regulation of cell spreading (By similarity).
Subcellular Localization:
Lateral cell membrane. Cell junction, tight junction. Membrane; Multi-pass membrane protein. Cell membrane, sarcolemma. Membrane, caveola. Note=Detected at points of cell-cell contact in confluent epithelial sheets. Colocalizes with components of the adherens and tight junctions (By similarity).
Sequence:
MSNTTSALPSSVPAVSLDPNATLCQDWEQSHHLLFHLANLSLGLGFLIPTTLALHMIFLRLLLMTGCSLFIAWATLYRCTLDVMVWNVVFLLVNFMHFFFLLYKRRPIKIDRELKSVYKRMFEPLHVREALFQRLTGQFCTIQTLKKGQVYAAEDKTSVDERLSILLKGKMKVSYRGHFLHNIYTNAFIDSPEFRSTQMNRGERFQVTIAAEENCKLLCWSRERLTYFLESESFLNEVFRYLIGKDITNKLYSLNDPTLSDKAVKKMDRQPSLCSQLSMMQMRNSMASTSDTDDVLNQILRGGSTGSSLQKNPLTKTSTTMKPIEEGLEDDVFESESPTTSQNVSKTTKKDI
The following text describes a protein:
Function:
Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of complex I subunit MT-ND1.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MAAATAAGGLRPVSFPRLLRAVGARGGLPWPRGGRAAAAGWSRPEPGGEAQYCAELLRKRDYEGFLCSLLLPAESRTSAFALRAFNVELAQIKDSITQKTTGLMRMQFWRKAVEDIYCDNPPHQPVAVALWRAVKRHNLSKMWFMKIIDEREKNLDDRAYRNIQELETYAENTQSALFYLTLEMLGVRDVHADHAASHIGKAQGIVTCLRATPYHCARRKVFLPMDICMLHGVSQEDFIRCKQEKHVRDVIYDIASQAHIHLEHARSFSKKVPVKAYPAFYYTVALDDYLYNIRKVDFNIFHPSLQKRNTLLPLYLYIRTWKKTY
The following text describes a protein:
Function:
Coenzyme A diphosphatase which mediates the cleavage of CoA into 3',5'-ADP and 4'-phosphopantetheine.
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MKCVVSRADDLKRMLDLSDVPTKSQGEQDAGVLILLHDDGSEKLKVLLCVRSRQLRRHPGEVCFPGGMMDDEDGQNVRRTAIREAYEEVGVNENDDYLVLGNLPAFRARFGVLIHPTVALLRRPPTFVLSIGEVESIFWIPLSQFLEDTHHSTFLIDEFYMVHVFQFDEYPTTYGVTALMCIVVAIGLLGKLPNFNLMGNLTISDMLDKHLDSIEIIRHVYEFASRKFEPKSKI
The following text describes a protein:
Function:
Required for the restriction of long-distance movement of the pathogenic tobacco etch virus (TEV) without causing a hypersensitive response or inducing systemic acquired resistance. Seems to not be involved in heat resistance.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Note=Present in sieve elements.
Sequence:
MAARQQQKGTGFGVQYEDFVPKSEWKDQPEATILNIDLTGFAKEQMKVTYVHSSKMIRVTGERPLANRKWSRFNEVFTVPQNCLVDKIHGSFKNNVLTITMPKETITKVAYLPETSRTEAAALEKAAKLEEKRLLEESRRKEKEEEEAKQMKKQLLEEKEALIRKLQEEAKAKEEAEMRKLQEEAKAKEEAAAKKLQEEIEAKEKLEERKLEERRLEERKLEDMKLAEEAKLKKIQERKSVDESGEKEKILKPEVVYTKSGHVATPKPESGSGLKSGFGGVGEVVKSAEEKLGNLVEKEKKMGKGIMEKIRRKEITSEEKKLMMNVGVAALVIFALGAYVSYTFCSSSSSSSSSSPSSSSSSTKPE