lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development.
Sequence:
MTTSTLLFVLAFVAGGLAAPWGADVPRCSTECPVTGSPKLAYQPDKTYAYAYSGKSTVQLKGVDNGDTETEWTAGVDLTWISPCDMAISFRNTKMDGARGPTAARTLERYPLVVAVVDGRVQHVCAHPEDEAWAINLKKGVASAFQNSIPSLSAVSSGITVTETDVVGKCPTKYEIETEGEKVIVVKEKNHRHCQERYPTPAALPAPWLKAPLPIEESKSQCRQEIANGIYTAITCQDKNIVRPAIGIYKYVEASQYSTLRFISESSDTSAISGIPSGELNIESLLYNHETMKDPQLAPELDELMKEICDKTKDTVEAEAGALVAKALHVLRRIPDTVVVETAQKVRQGHYCSDSARLESIFLDAVAFIHESGAVKVMVNEIENGRATGGRLALYTAALYLIPRPNIEAVKALTPLFESPRPMPSLLLAAATMVNHYCRHTPACYEKAPVARIAEILANRVQTHCSPSAGVEDNEVALAIFKTIGNMGVATPAVTRAAVHCIEVEGLETSVRVAAAEAFRQANCFRPAVEKLVDIAVRPAFETEVRIASYLAAVRCAEQEHLETIIEKISKEENTQVRGFVLGHLINIQESTCPAKENLRYLLANVIPTDFERDFRKFSRNIDVAYHAPAFGMGAGLESNIIYAPGSFVPRAVNLKMKADVDETHMDIAEIGARFVGIESIIEEPLGPQGYLRTATFGKIMEDITGFAGEKGYKVMEQLKHTLRTRRSIDSSVIADFFGKLYGKSRSHTHAELFARFMGHEITYADVAGSLKGVTADTLIETFFSFFENSLEHMKDLNLNTARTAQLSMDYSLPTIQGTPLRLRLAGTAVAGLKMEGNVNIAQILSDLGNSQTGVKFFPGLSVHATGFVGFDWLLARVGIEMQNTISSATGAAIKIRTTENKKIEMELEVPEKMELLNIKAETYLVKAVGKKMTEISPSSMRDVRIQRNSCIGALEPVFGLKVCYDMNIPDVFRANALPLGEPAIAKLYVEKADPSMRGYLVTAAIKNKRGNKVIKMNVEAAGASTPRRAEMTLSYTKEEGSHIVSAKLDSSSIAAGVWTTLTNEQGHKAMETYVNFNYGQIAISRGIKLEAIAREASVGEEFQVNVFSSGTRSFPSESHIVEARFIKKTSGPEFNVDVICRTKNALAELFDLNIEVGADFMKFSPKNLYPARYIPKTRIVLPVNLRKMEINAATAAWKLISYIRAGSQSGGSREFISALKLAKGRKDFISVQATHTIEGTFPQNIIIKNVATAEVGRSSYKAMYDLFYHSEKMGASLEVLQAAGNEKVAHLEAIYELSGSKYCTKFLAEIPGYIQPVKVEAGIEQGAEGRYTLESAITYGQRTVLEASGPIMARFSSKIAKLQANIKVRAMASEPYIIGANVAFGSKKQMIAMEIKGRSEAVIGLEWKMVRESSEKTTVGIVFVLPALIENKIDAEITDGLIHVSFNNLVLPKTSSRRRVKGFADVHIAEKKANVEFSWDADNAPEKKLVLDASLISSSANPGHAEIHGNIVIAGEPFHAKLVLTAANLVEHMEGENGFKLILTTPSQKTIVLGASCDVQVAGATTKVISTVEYKNMKDRKYKYASVIAYEKLGGPFDYAVEAKVTYKQPGTAEIKLGTAVKHHWTPEEHVVAVRVEADAPILKTPATIEFSIHNAPNAFVGFCKIERNAPATVFEWNVQITPEGGIEAVEAGVDMKAIIEVLKIVHAAATLQEESYETYGPHTSQYQYRFTRPSPTSYTMQMRTPTRTMEGRAKLSPRESGIKFYPNKGKTESKYEIGYKANHEGRWGGHASKLEVRMNHPVLPKPIMAAVQYTVAEETTKGTIELDIFPEEANKITGSLETQRISENAIRAEAFLTSRMLKVNPKAIITAAYAPETVAFDVVFHKTPSAAPIFAIAAKYDKTAAHNAAATFTVKMEERPVFEITAVTEPEEAATCNGIRMRAVAYAATFGKYNVISKMCRPAFIEVTAMRPGGAKEYIAKLGLRYPDAAEAGVYVASGRAGETHGVAVAAVKLASPTMLKVEMAYEPQEAEAIINEMTEEFEKIAASFTSVEMEVVEFLKQEAAAKGIQFPSSQLVNLLGVAKEEIAEIYRDIVSEAIIFDTEILGDILGSPVVSFISRVYFGVWSEIIHLQHHLSVSLIQTIERFQQELGSISEILMEVVMTAARMAETGEVPGVVFDALEEIKATKVFRIVRREVDAILEEYPEEYEAVKHIVHNVVAILKRDVGIVRERLMEIPAVLKIIDYTMYHFHSERAFAAEAEKLVSLMLNELLFVSMEREGNGVAVRIPLHRPLYSLTQVAQEAVPNPVTMLENLIFAYVDYIPIPVSDAIWAFYNLVPRYITDVLPPYPRTATVVGGSEILTFSGLVVRAPRSPCKVVLAAHGSHRLMMSHPQASAPAQFELKTPAATVMIKPDFEVVVNGQPLAGSQQTIGNVRIVNTAEHIEVGCPLMKVVVAKAGEAVAVEASGWVFGRVAGLLGPNNGEIAHDRLMPSGAAASNPRDLVAAWQEDRQCSTPEVPRAETTVARLIQCEALLGIRSRCNPVVHPQPFIKMCHAAHKACDAAQAYRTVCSLRGVGEVFPLGC
The following text describes a protein:
Function:
Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
Miscellaneous:
MISCELLANEOUS: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
Sequence:
MDEEAEVAEIAVLGGVGFNSHKDCESHPVTTPYGRITAYLTSIKGRSVVIIPRHAEEIHIPPHRVNYRGNIWAAHSLGAKRVISTNSVGSMRGHPVGSFVVLDDFIDFTRSRPSTFHDDKTVHVDVSEPYCPEIRASLRYSLEKRGISYTEGVYACTEGPRFETRAEIRMMSQFADVVGMTGVPEVVLAKELSLCYASLSIVTNQACGMTTQKLTADEVTEVVGKAQASIFKILSDAIGKIPETRNCMCRFAKEGACL
The following text describes a protein:
Function:
Probable S-adenosyl-L-methionine-dependent methyltransferase.
Sequence:
MGVTVANGGGAAASAGASSSTRTAAKQMKKSKKARKALHIAPPRMKSRRKARQVTTNFHRLTHELDRLKQQKPAAPEQQQQQNERLSEINKQLEQLGGRQAYQDASILNTSFHRTSKWVFQLLTRFERRPKAKQPPLRVLEVGAINTQLLSCPWLDVRAIDLNSRHERIEQRDFFSLKPTGEFHVLVSSMVLNCVPGADKRGEMLRLYREHLKEGGLLFLMLPLLCLRHSQFMTYARFTKILEAVGFRVRETKDSPKVAFFCLERTEAPDDKASFPHKLLVHGGKRNDFSVVI
The following text describes a protein:
Function:
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
Subcellular Localization:
Cytoplasm.
Sequence:
MMIKVASITKLENGSIVTPKGFSAIGTVNGLKKEKKDLGAIVCDVPASCAAVYTTNQIQAAPLQVTKDSITAEGKLQAIIVNSGNANACTGMQGLQDAYEMRVLGAEHFGMKENYVAVASTGVIGVPLPMDIIRKGVATLIPTKEESEAYSFSEAILTTDLITKETCYEMIIDGKKVVIAGVAKGSGMIHPNMATMLSFITTDAHIEHNVLQTALSQITNHTFNQITVDGDTSTNDMVIVMASGLSETRPINMEHTDWETFVGALQKVCEDLAKKIAQDGEGATKLIEVNVLGAQTNEEAKKIAKQIVGSSLVKTAIHGEDPNWGRIISSIGQSEVAINPNTIDITLQSISVLKNSEPQTFSEEKMKERLQEDEIVINVYLHLGEETGSAWGCDLSYEYVKINACYRT
The following text describes a protein:
Function:
May function as sodium-coupled metabolite transporter across the chloroplast envelope.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Plastid, chloroplast envelope.
Sequence:
MKEIKQKELYQKIKWKFMAVNMTKSWMLDTTTCILQSKKKATSNGSFQGDNPLDFSLPLIILQIVVVVAVTRIISYIFKPLRQPRVVAEIIGGVLLGPSGMGRSTVYMNTIFPDSSMINLDTIENIGLLFFLFLVGLELDLRAFRHTGKKTILIAIVESYILALVVSLSGSGSPLISLLVFLCRIGFVVFATVVICPFIIWLAFKSPNGEKVKEIHICITLLKVLVGGFNTDMIGIHALFGAFIIGIIIPKKGPLAGGLVEIIVLNIGKDRGVLNDESFAILVTMALFTTFITHPGSYGSFQTSTGPSKVLTSKTKSSRGMLRRGITMYFMHLMDLSEIPSDISLVNKARRNNGLPFWNNRRSKGENVAIAVAFKSFDQLNHVKIRSMMVISDLVDIHEDIVDSSQQKCAALIILPFHKYQRFADDMESLGIEFLLTSEPESITSRHLFRRDPHRPWPRRIISKKRMGTKEEVIVELKGLGKFNIILVGRMPPIKQLDDRSDCNELGPIGSYMTSQEFSTTASVLVIQQYCSKETEKLSFRATEVYDIVESSQSECPHCRQTRLYRWS
The following text describes a protein:
Function:
May act as a co-chaperone and regulate the ATPase activity of heat shock proteins.
Sequence:
MASNKQKLAVSILNFLKVSMKEDAENAESLQVAVECIRDVFGVDENDSTLQVSAPLSEIFDKFIGENNTNTTTTTTTTTTKLSKEELLNQTYSEIPYELLESFKQFITILEQKGAFANEDSCETVIKATKQKFMESKAGEVKAIAEKLKNEGNAKLNEGKHQEALSCYNKAILYDNTNAIYFANRAATYSALQNFEKSIEDCLEAIKRNPNYGKAYTRMGSAYTSLGKFSEAMEAYNKAIELEPNNETFKASLANAERLAAAANNQAPAMPNIPGMPDLGGLDFGSLLSNPAIRGLANNLMSDPKMKEMMDNGDMASLLNNPDLLKMFGNLGKK
The following text describes a protein:
Function:
Involved in cellular auxin homeostasis by regulating auxin metabolism. Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGFRSLFGVASMLVLQVLIICVMGAFMATGRCNLLPADTRKVLNKCSSPSRPSPIFTSLTKTVTLQDIISWWFMPIDVGISFFAGGVLGLLLVKVLKPLTHLEGLIIATCSTGNLGNLPLIIVLAASFPMALGGFYIWTYTCQLIQTSSSKYKELQAAKDASKAPNIHQNAGRESHLLKERDGEQRTVVSLRSSRIRPWAIAGVICVHYVILPVIGIGVMKAASKLDFLASDPWYHYVLMVQTVTQLFDVGQEECSVLFLWTYLFAFIVLTIWSTVCMWILS
The following text describes a protein:
Function:
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MGLGDFFNEKLNNGFSAVLTGIVALSTLFTILLLTLPKQYDPYEDKAIKYVDENGKEIQVKTKDGKTALRWKQGRTVQILVLGDIGRSPHAESCAESEIHPDIVSNPLIEVVPLVPAPESLRPSSKLLFPIIAPLKVLWQVYSLWRALGYRSGPARWMFVQNPPSIPTLAVAGLLCFLRNTDLVIDWHNFGYSILALKLGASHPLVKISALYEKLFAKAAAHHITVTNAMARVLRDDYGVTAQALHDRPASLYRPISSQEKAKFLARLPETAQYAQDLLPSSKTPWRLIVSSTSWTADEDFSLLLEALSQYSAEATSKVHLPKIVAIITGKGPQKEHYLEKIRKLNQENKLINVVILTAWLTPEDYALLLASADLGVSLHTSSSGVDLPMKVVDMFGAGLPVVGWGKFEAWPELVKENVNGKGFESSQQLAEQLIDLFGESDALLKQLKEGALKESENRWDDEWDKVGGQLFKLI
The following text describes a protein:
Function:
Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
Sequence:
MYQVAICDPIHAKGIQILEAQKDIVLHDYSKCPKKELLEKLTPMDALITRSMTPITSDFLKPLTHLKSIVRAGVGVDNIDLESCSQKGIVVMNIPTANTIAAVELTMAHLINAVRSFPCANDQIKHQRLWKREDWYGTELKNKKLGIIGFGNIGSRVGIRAKAFEMEVLAYDPYIPSSKATDLGVIYTKNFEDILQCDMITIHTPKNKETINMIGAKEIERMKKGVILLNCARGGLYNEDALYEALETKKVRWLGIDVFSKEPGIHNKLLDLPNVYATPHIGANTLESQEEISKQAAQGVMESLRGSSHPHALNLPMQAFDASAKAYLNLAQKLGYFSSQIHKGVCQKIELSLCGEINQFKDALVAFMLVGVLKPVVGDKINYINAPFVAKERGIEIKVSLKESASPYKNMLSLTLNAANGTISVSGTVFEEDILKLTEIDGFHIDIEPKGKMLLFRNTDIPGVIGSVGNAFARHGINIADFRLGRNTQKEALALIIVDEEVSLEVLEELKNIPACLSVHYVVI
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Sequence:
MTIALETQNLEKQFGGLRVTRDLSLKIEQGARHALIGPNGAGKTTVINQLTGVLKPNSGRILLEGQDITDLPVHKRVLRGLSRTFQINQLYPDLTPLETIGLAVSERLGHGGDWWRRMGTRSDVNGEIADLLTRFHLLDVMNEETVTLPYGKQRLLEIAVAIAAKPRVLLLDEPAAGVPESERHDILAVVGALPRDVTVLLIEHDMDLVFSFADRISVLVSGALLTEGPPEQVARDPQVKAVYLGEEAVNV
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
Subcellular Localization:
Nucleus.
Sequence:
MALSPASRSSSSSSETNQRQLNHRVIFPLLLATIANIRYAHSRSILKRTLQNYMIIIKTTPPPSVEALLPHGLLSLLPVLISTTETYPSLCILTAEVIGSIALNSMDANSELAADDEILGSFVGALCYCTRMVKEEKKKMKKKVVMALCNAILDLSTNPCSRELISQSLAGFCADMWADKFMKNKLLIVVLDTLLMLVNTYSIDILASIPRELLSTTLASLKKLWIMLQNQQSPTQSGEEGQEYRCRKKHDLAVAIFRLSMNDVQYPSYDIDMVKRDIFGSSSKFDFEHFLSNYWEDSPFLFVGSSLNSDNKNIVFGSLMKTFVGKSMDALLSSILNCTISCPPLNSDEPDIFNFLEEMKGELGSPLVYGQDIRVIKTECIHSSLQKEIDFFDYDKTNLKGILVDDIQKYKQAFHQGFTIALRGMEFRSKKIAAIAEGLAYLFGMPSVGVNLYLTPSGSQGLSRHYDDHCVFVCQIIGQKKWILFPNPAAPVLPRLYEPLENLSCLNCQGKPLDLHEGDILYIPRGSPHEARTMIDDIKDKPVESSVSSLHMTFSIEVERPFEWEGFAHTAVDYWSKTQNYASHPYHGHSQLQVPDFLVNLLHLAISTIGVNEPIFRKACMVSMCSSNAESNKSIFQCIVNAIDWKCSFLEVMKTAKVIVDEGNDEALHWVRWVQYLVPRNNKRENDKRDAFCEVHEELECFIELSDEKNNVDCIETMFIELKSEFCRQVVFDDVCKSFQKLLEDYRKIRQQYTNGMLSLHCDGF
The following text describes a protein:
Function:
In vivo, intraplantar injection in mice cause spontaneous pain behaviors and paw swelling. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Miscellaneous:
MISCELLANEOUS: The secretion of this protein into venom follows a seasonal pattern. This variation is synchronized with melittin variation, i.e. their production increase in the same months.
Subcellular Localization:
Secreted.
Sequence:
MQVVLGSLFLLLLSTSHGWQIRDRIGDNELEERIIYPGTLWCGHGNKSSGPNELGRFKHTDACCRTHDMCPDVMSAGESKHGLTNTASHTRLSCDCDDKFYDCLKNSADTISSYFVGKMYFNLIDTKCYKLEHPVTGCGERTEGRCLHYTVDKSKPKVYQWFDLRKY
The following text describes a protein:
Function:
Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.
Sequence:
MAPVVLLSVLSLDWEMGSCLAGDYVHELSVFKMPIKGYFCHCIDFPPKYQNWEQTDPLDLFGAPALKNEALASRLVSFKENMATWTRASSRRLHTQIITLVPKPFWTLYPRLSKGGHSLQVGWERGSVFEQAKALKSGSLKVLDVSQREELKARPTGLNTVNMLKLFAWILTTPCKSHKLPRPEDANRGNGNKPHLLMAKPTPMRKDYTLESTSLRCTRGVVDHAGFQLVLDCPSGLRWACHCHFVISPSKGCTLQWGKMRNLLSLLRHLGGSCSGPYHCVEDCPTPSSRYGPGNAADGLSRLRGKPLKAPRKRKVASRMGKLRPGLGLLVLLLPRIKLQGRNDCLYTSQRSHEPPFELYKFSVVHLRESGGLVKELLLVQGPKVGGAFAAFDGNHGAVLQVIHRFPT
The following text describes a protein:
Function:
Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.
Sequence:
MTKRMKYKELINELYKKRTNGIKLGLNRVISVLEKLGNPHHSFKSIHIAGTNGKGSVSKIIYCLIRAQGLSVGLFTSPHLTRFTERIIVNDIEISEEEVEHLIEKIKPFSDELTFFEYVTVMALQYFKEKGIEYAVIETGMGGRLDATNVVNPLISVITNIGLDHQEFLGADLASIAKEKAGIIKNGIPVVSSSQKKEVEKVIIKKAEEMESPLFIYDRDFIGVLKSMSLEGIVFDFYPFSFQPSTSSLQSNLFLPLTGFHQLENVSVALKAFINIYPMYNENAIKEGLKNVKIPGRLEIIYDKPLAVFDIAHNPDAAEVLIKSLKTLTDKKPVVVFAMMRDKNVNEFIKCFENYAYKMIFTVPNYERALTYKELLKRLNDKKIDFVPEPLEAFRNAISLCKNNSDIYVLCTGSAYLVGEIKERLGEKTLHRSLGEIL
The following text describes a protein:
Function:
Functions both as a transcriptional activator and a repressor of multiple genes encoding virulence factors as well as genes involved in environmental adaptation. Plays a role in alginate production via the activation of AlgD which is the first gene in the alginate biosynthetic operon. Also regulates the transcription of genes responsible for type IV pili localization and twitching motility. Mediates transition of P.aeruginosa biofilm infections from colonizing to chronic biofilms through repression of the psl operon. Also represses its own transcription by binding to two sites on amrZ promoter, amrZ1 and amrZ2.
Domain:
The C-terminal is essential for tetramerization as well as efficient AmrZ-mediated activation and repression of its targets.
Sequence:
MRPLKQATPTYSSRTADKFVVRLPEGMREQIAEVARSHHRSMNSEIIARLEQSLLQEGALQDNLGVRLDSPELSLHERELLQRFRQLTHRQQNALVALIAHDAELAQA
The following text describes a protein:
Function:
JanA and janB regulate somatic sex differentiation.
Sequence:
MPLADIADVDIDPKGVFKYILIQVTDNSTKQQKFVVRGYYRCSFHDDILQETKSSAPSDLKLKCVGGGRIKHDEIGKDILVYGYSYGYGRADHQIAVDILKQKYPDYNIHFSNDGY
The following text describes a protein:
Function:
Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MLVKTFEAVDMSEALRMVKAELGPDAMIISSKKERKKGFLGFFSKPVIKVTAALEVKPRQPAPNPYREAQEQHLSAKEMLENSMLAPLARELKDLRLKVEQMTRQEAEAKAKAAEAQSREESAAAAEAPAAREFNPRSIPKQDLEEMKKILFKTLAAKEAGAEQSAEKADADPAPAKAPQTETEKASGGIKAALRVVVTELHRKGLERGAIRAVMDHLKPEARKGGTVEAIRSFLPQAFKSAIKCSGPLTVKKNGPRIIALVGPTGVGKTTTIAKLAAHYALREGHRAALITIDNFRVGAVEQLKTYSRIMGVPVEVAATAAELEAAIELHSDKELILIDTAGRSHKDSEKIEELKGFLESRFAIEIHLCLAATTRDREVLEIVERFGVLSVSRVIFTKLDESESYGSIVNAHLRTKFPLSYFTTGQRVPEDLEIATPGRLAGLVLGESKQ
The following text describes a protein:
Function:
Converts protoheme IX and farnesyl diphosphate to heme O.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MLTDFFWWSISYESTTVLRRALSSLSAARVCRFREPESCRTIKQVGKTMLHITAARHAQLFRLTQRRLQSGTFKACPYHRTKEGSPTVMAQGAMEHCPVVGTTPHMGCPVEARLCDRRPPTMSIMVSQMGKSQLSAYVAATALAGYVIAGGTVPLVAAAVTAGTMLQSCSANTANQIIEAPYDKLMKRTCRRPLPMKFLSPQAATAISSMELTLGTGLLYCVSPPAAALGVFNWFLYVCIYTPLKRVSALNTWFGSIVGGVPPLMGGVAVAGIITPPVWLLATFLFVWQIPHFNGLAFHCRRDYEAAGYKMLAFYNPWRASFYAVALSVLMAFLTLVCPTLAGMEVEGMWYYSVTAAANALMIYKSLLFHNEPVRHCRGCFVFSYVYLSVVLAAIMLNHIQPMHLAQRAIDYVAAEATKASTPSSAVVSTAET
The following text describes a protein:
Function:
Binds to the 23S rRNA.
Sequence:
MFSHTKKVGPTGRFGPRYGLKIRVRVRDVEIKAKKKYKCPVCGFPKLKRASTSIWVCGKCGAKIAGGAYTPETGAGKAVMKAIRRIVERKEE
The following text describes a protein:
Function:
Catalyzes the addition of fucose in alpha 1-3 linkage. Unlike fut-1, does not add fucose to Man-alpha-1->3-(Man-alpha-1->6)-Man-beta-1->4-GlcNAc-beta-1->4-GlcNAc-beta-1-Asn (M3), Man-alpha-1->3-(Man-alpha-1->6)-Man-beta-1->4-GlcNAc-beta-1->4-(Fuc-alpha-1->6)-GlcNAc-beta-1-Asn (M3F6) or GlcNAc-beta-1->2-Man-alpha-1->3-(GlcNAc-beta-1->2-Man-alpha-1->6)-Man-beta-1-4-GlcNAc-beta-1->4-(Fuc-alpha-1->6)-GlcNAc-beta-1-Asn (GnM3F6) acceptors.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MRVRPASVYRYLLLGVCALLGIYTVYSIIGYDDGSHVPIHRPQRHLYLTVSQDRIGSRFGKLAPKRILYWTTIFGATVPSTALSDCPGLTDRCVIDTNRHQLDSADAVVFHAADISKFPLPVSRKPDQIFVFNSMETPDNSGRFAVPDGFFNWTSTHLYSSDAIHKYGTFLIPTQIAESRGFKVQSYYVQPKRLVKTMKGIFGLISNCHTKSKRELALQELGKHINVTIGGKCASDDRLKSICPAGVECIDVFEQYPFYIAIENTVCNDYVTEKIWSRITVPSIPIVMRRRVYQNILPPKSFIAMDDYKNPSEMANHLRSLEANSTAYGEYFEWRQKGLWTSAPWNAPGYRNGLCRVCELLWKAKDNETEVYKSYDNIWKWFDNESQCETDEFVRSWLSG
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MDRLTQLQECLGKLTEIFFTSTGVLQRDAPLMSTNPDLPITSWKSEQIETNWLANKDLAKTAAKDIVETAKVIDFLIDQLPGISENEEEQIRILGALEEENRIAGIEMEQAIEEAEKLRGEIQTSLRRIADEHTDLHVKISTMLK
The following text describes a protein:
Function:
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MIVSLTISLFWCEELIMNPLVSAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
The following text describes a protein:
Function:
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
Sequence:
MQQHNPIQIHVEDTNAEATMAKISAIKHKYFQDEFSEEFVKGTSKKDVLIHRGYWCRFNIFHRIVSTYISKQQKCNVISLGSGYDTLPYIMWQTYQNKEFTFVEVDLPVVVDRKIKKLKESNKLKTLLGEYIISQNKLSAKSENKNYLLFGEDLCNTEQLHQSLQSLDFTIPTLVYAECVLTYIKSEATTRLLDGLTKWFPHLTFLNYEMFNPSDQFGKMMVRNFEYRGCPLVGIDAFPSLQAHKDRLNQWFNYVEIYDMKTLYQIATDPEERKRIEKLELMDEWEEWNIMQSHYLVSLANKDQTELIVNLKV
The following text describes a protein:
Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence:
MDPNCSCSASGSCSCASCTCKACRCTSCKKSCCSCCPAGCAKCAQGCICKGASDKCSCCA
The following text describes a protein:
Function:
Catalyzes the last step of the oxidative degradation of choline to glycine. Converts sarcosine into glycine.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MASLSRALRVAAAHPRQSPTWGMGPCNLSSAAGPTAEKSVPYQRTLKEGQGTSVVAQGPSRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTSIRVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTERIEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFSLFDLDWEVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGWFHPQGPAPVLEYDYYGAYGSRAHEDYAYRRLLADEYTFAFPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSRPPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAVGGAVAQHNWSHVTTVLQDQKFQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGHLVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLKSPVLFLGREALEQQRAAGLRRRLVCFTVEDKVPMFGLEAIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGARAHLKSPFDPNNKRVKGIY
The following text describes a protein:
Function:
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Sequence:
MSRHHQGVVLTAYHSSARDEPQTGPGPDPQLAASSRKMGHYTLQQNHDPQHRDKHETAISADSSLLPKPNSAPSTKSQLSSSPKSTISPRHSPNTRPRPTCQRSSSQDSLDELQMDDYWKEVENISCSGGGGGKGEGEPQEEEHQKNPEEGEQEEAWLTEAGLARLFDDSLAADDQDQEEDSAVFLSTLTRTQAAAVERRVQQTLLRRRNRQHLPDVRDIFKPPEKDEECHQLQRRSENGPKDASAAETETELDVEVAFSEQALSYWDNQQKAKVTNNLNPPDDKLPNFKVLRVKTGQTRAEDLSPLDMIKVRRLLLVEMTALFDTAGIDLKTHKPVKLKTRDSGLFGVPLNTLLDQDQRRVPGTKVPLILQKLISHIKEEGLDTEGLLRIPGAATRVKALCQELDSSFCEGTFPWQQVKQHDAASILKLFIRELPHPLLTVEYLNAFIAVNKLPTKKQQLQALNLLVLLLPEANHNALKALVEFFQQVIDHQAQNKMTLNNVSVVMAPNIFMFKGFRSKVSEHKEISMATSTANIVRLLIRYQNLLWTIPKFILDQVRQHNMESQRKPNNQRAVRKLLKKITTDKPSEKPIPEESSQGFIRVQAPQFSKVSMAVQLTEDLQAVDVLTRFLSQDRLVTAKKEDLCLFEIGGNIKERCLDGETYMKDLHHLNPTAEWVIKLVQR
The following text describes a protein:
Function:
Structural component of the short tail fiber. Adhesion protein that binds irreversibly to the lipopolysaccharides component (LPS) on the cell surface of Escherichia coli B strains during virus attachment. After at least three long tail fibers have bound, short tail fibers extend and bind irreversibly to the core region of the host cell LPS.
Subcellular Localization:
Virion.
Sequence:
MSNNTYQHVSNESRYVKFDPTDTNFPPEITDVQAAIAAISPAGVNGVPDASSTTKGILFIPTEQEVIDGTNNTKAVTPATLATRLSYPNATETVYGLTRYSTNDEAIAGVNNESSITPAKFTVALNNAFETRVSTESSNGVIKISSLPQALAGADDTTAMTPLKTQQLAIKLIAQIAPSETTATESDQGVVQLATVAQVRQGTLREGYAISPYTFMNSSSTEEYKGVIKLGTQSEVNSNNASVAVTGATLNGRGSTTSMRGVVKLTTTAGSQSGGDASSALAWNADVIQQRGGQIIYGTLRIEDTFTIANGGANITGTVRMTGGYIQGNRIVTQNEIDRTIPVGAIMMWAADSLPSDAWRFCHGGTVSASDCPLYASRIGTRYGGNPSNPGLPDMRGLFVRGSGRGSHLTNPNVNGNDQFGKPRLGVGCTGGYVGEVQIQQMSYHKHAGGFGEHDDLGAFGNTRRSNFVGTRKGLDWDNRSYFTNDGYEIDPESQRNSKYTLNRPELIGNETRPWNISLNYIIKVKE
The following text describes a protein:
Function:
Unknown. Cellular response protein to viral infection.
Subcellular Localization:
Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein. Note=Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption.
Sequence:
MMGLGNGRRSMKSPPLILAALVACVIVLGFNYWIASSRSVELQTRIVELEGRVRRAAAERGAVELKKNEFQGELQKQREQLDRIQSSHSFQLENVNKLHQDEKAVLVNNITTGEKLIRDLQDQLKALQRSYSSLQQDIFQFQKNQTSLEKKFSYDLNQCISQMTEVKEQCDERIEEVIRKRNEAPGSRDLAETNNQHQQALKPQPKLQEEVPSEEQMPQEKGDVPRNKSQIPAPNSESLGLKPQVQNEETNEIQAVGEEHQQASIQGQAVADGTRVGAEKLDQHTQLPAGLLARPEEDSQYPEREQLVIRDRQEQQRASEEGGGQKNPGDEYDMDENEAESEREKQAALAGNDRNINVLNADAQKRGIINVPVGSERQSHILNQVGIHIPQQA
The following text describes a protein:
Function:
Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.
Subcellular Localization:
Secreted.
Sequence:
MEQLGCPDVSRKGCGLRSILLQVRDLGLGYDSDETILFKYCSGSCPHTRSNHDLTLNNLLLSGLLLHPPPGEVWHNAPCCRPTHHEDMAFLDNSHRWHKVEKLSAAGCSCVG
The following text describes a protein:
Function:
Essential for vacuolar biogenesis, maturation and function. Involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeting to the vacuole.
Sequence:
MTTDVKEKATFKLLDLIDSVTGKKSLLLERDLSGILGQIVTTNTLQEHGIPQVYWFNENIPNDIEKKTIYLCRPTYENAKLVATHVRQFQRDMLRIESTVIVLPTSNILFETVLQEEGVFGELLVTEWPLHAVPLDKDLLSLELGPEKLEESLLQRSTDALIDFERTHGRFPRVSGRGPYAAKMLELLEKTYQEEATINFGKVEGEISALYDSVLLVDRSLDRITPFLTQLTYFGFLDEILGIQQMNVKLPSSLVNRNEASNTGPMKKFSLSSSSSQITKEIRDINFNCIGPYLSKIARKLSSDFEGRRQAKTVNQIRDFVSKLGSLQSEHTSLNIHTGLAETLVQHTKNNYFQKLLQLQHLLVSHADSFTQFNLLDEIIYAEAPVEEVFRVLCLASITTNGLRRKDIDHYRREITQTYGYYHLLTFQALIDAGLLRLRQSTNISLQKSLSYSTWLNTYPLVKDEVDEQNPEDIAYTYSGYGPLSVHIAYDILKGRDNEEKILKLQNMPGTYVDKWTLDQEKVMPKNLKTNVPGKRRVLVFFIGGCTYTELAAFRLLQEKEDLYEFTFMTTGMVTGSSLIRAFIPNIESLNE
The following text describes a protein:
Function:
Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
Sequence:
MATTNDHPGERAAADPVKLIGIRETPLSVDEVFGAVGDDASGGTALFVGTVRNHDGGTDVDRLGYSCHPSAEAEMRRIAEKVVAEYPVRALAALHRVGDLEVGDLAVVVAVSCPHRGEAFDACRKLIDDLKHEVPIWKHQTFSDGTEEWVGA
The following text describes a protein:
Function:
Binds to the 23S rRNA.
Sequence:
MIIMDVSVQRRMAAEILKCGIERVWIDPTQLDRVKMAMSKDDIRALIKEGVIKKKQKKGISSARVKKLKEQRKKGRRRGPGSRRGAAGARTPPKERWMATIRALRKTLKQLRDSGKIDRKVYRKLYRMAKGGAFRSRSHLFLYMREHELLK