lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
Subcellular Localization:
Nucleus.
Sequence:
MAGRMPPGGRYGPPPSWQPPNGYNGQVGYHPPSMHPPAFPSHHESHPYWQQPGHHRPNRHESEFDRHAHSRDQYRRRDQYRRRDHYQGRDHYQGRDQYRGRDHGRDSGHDRHRQYSRYEQSSGPPRRQRSAAPLSPAMQKELDSLFNKKYTFPAECFAPIEAKQLFVAPEEPIDPAMQALKDRANGVKGSLDDMDQEARPGLIFLASDSWFAFTLTGPACPLQLWYRTAKLHNPTKNVPFTLSRRFRVELPTIAWCKMYEILARYKLLQQHQEMPFATVHVCEAPGAFVAALNHYLRQLYHRELKWNWTGLTLNPYYEDNNPIDMVDSDTLILLTESHWHFGHDNTGNMMHAPNLKGLRDRVLQQEMRVELVTGDGAFDTSANPAEQEMLTAQLHYCEAVAALACLAPGGTLVLKMFTFFERCSAALVYLLGGLFETMDICKPATSKAANSETYIVAQRFRGCDHAILDRLLAHIDPSHPVDAAGQRLALLPSASFTPAFTQHLAQAADEISRFTEDHIQHVIDQSRRTVPANRDELINYQRAVAEEYIQRFGVTEVPARLQLSPAVYLDGHSNLSTSSRAGTGTRRPEDHGGLQGATLKERQAHLRSTVKRQQAERHKEKPDATNADDGTPSQKRVKIQAQGLQLDAEDRPSSERPADPPSRPLSIAERMMQKMGYKPGQGLGRDGTGIVQPVQAAPREERTGLEAARTAFAQRDVKAWQQHAGEAGIVLVSPAFDWGAFAGSGRGRAEIDMSTEALSQVAAGLHLLRPGGTLLVRLAETFTRLTASLLHLLCSTFATCRLVKPLTSAPFASECFVVCRDYRHVEVALQSVLSVWQAISTPAPGPDLGVRRELLAFVGMSQLLEPTFYRHVVNATERFTIRQISSVQALATLLSEADGPLIRVPVLLEEARQGEDCQELDVDTEDPMERLIVFLQQSQMTELQLDGAVPM
The following text describes a protein:
Function:
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
Subcellular Localization:
Nucleus.
Sequence:
MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKAPGRGEVGKLRIAKNQGRTEVSFTLNEDLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSDKLSLEGIVVQRAECRPAASENYMKLKRLQIEESSKPVRLSQQADKVVTTNYKPVANHQYNIEYERKKKEDGKRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYRHYQTEEKSD
The following text describes a protein:
Function:
Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein. Cellular thylakoid membrane; Single-pass membrane protein.
Sequence:
MVKKEAVRTDSTEDNSVDNVQARSNFIAATKDELAKVVWPSRQQLISESVAVILMVILVSTVIYFVDQIFGWITKQPFLFG
The following text describes a protein:
Function:
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature (By similarity). Mediates anti-angiogenic signaling in response to SEMA3E.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Cell projection, lamellipodium membrane.
Sequence:
MAPRAAGGAPLSARAAAASPPPFQTPPRCPVPLLLLLLLGAARAGALEIQRRFPSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVFRAPGLTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNPTSPQDCPRTLLSPLAPVPTGGSQNILVPLANTAFFQGAALECSFGLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQCLGREDLGHLCMWSDGCRLRGPLQPMAGTCPAPEIHAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKEGKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTIATLQLGGSETAIIVSIVICSVLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLSEEWLLRENIEAKPRNLNVSFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKKDNTLGRVKDLDTEKYFHLVLPTDELAEPKKSHRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNIYECYSEA
The following text describes a protein:
Function:
Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGLQLPLGATCVIERQNGSETHEVESEVVGFNGQRLFLMPLEEVEGVLPGARVYAKNISAEGLQSGKQLPLGPALLGRVLDGSGKPLDGLPSPDTTETGALITPPFNPLQRTPIEHVLDTGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKDFIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGGSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFKQLLSSFQRNRDLVSVGAYAKGSDPMLDKAIALWPQLEGYLQQGIFERADWEASLQGLERIFPTVS
The following text describes a protein:
Function:
An odorant receptor which affects chemotaxis to the volatile odorant diacetyl. Specifies AWA neuronal cell fate via the odr-7 pathway.
Subcellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein.
Sequence:
MDLTVFNSFLKTAQFVGTCIANPLNIFLIYLILTKSSKKIGNYKYLMIYVSIYEILFSCSAIVTEPLLHSFTTRVIVIVDVHNSIFSREICSILDCLMCAMYGVSMNVFALHFLYRYATLFPKSKKLFDGARIIFWLTVPQIYGVVWLVTYYAVFRESPEYTEFIRKTLMENLDINVDDVVYVGPYYYMEDKNGIHDMDWTAFWAMAIVWLLIMSSAVTVFICGYGCYKKITKGLEVSSNSKQTKSIQKQLFYALVVQSAIPFLLMYIPSTVVLFCTLIQLDVGSASLFISYSIAIYPVVDPLPTLFIVQNYRNAVKKMITRTWNIVTRKKDMNSSAQIPSSNKTTA
The following text describes a protein:
Function:
Potent plasminogen activator that converts plasminogen into plasmin. It forms a 1:1 complex with plasmin, which in turn activates other plasminogen molecules.
Subcellular Localization:
Secreted.
Sequence:
MLKRSLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASYFEPTGPYLMVNVTGVDGKGNELLSPHYVEFPIKPGTTLTKEKIEYYVEWALDATAYKEFRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVVIEKK
The following text describes a protein:
Function:
Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step. May play a role in detoxifying endogenously produced glyoxals. Involved in protection against reactive oxygen species (ROS). Important for viability in stationary phase. May negatively regulate TORC1 in response to nutrient limitation.
Subcellular Localization:
Cytoplasm, P-body.
Sequence:
MAAKKVLLALTSYNGDFYEDGAKTGVFVVEAMHPFNLFTEKGFEVDFVSETGKYGWDEHSLIPDFLSGKDKEDFDNENSSFHKALKNVKAAKDVKASDYDIFFASAGHGTLFDYPKAKELQGLAEDIYANGGVVAAVCHGPAIFDGLKDKKTGKPLIEGKAITGFTDIGEVVLNVDKIMKDKGLLSVEDIAKKYGAKYLAPIGPWDDFSITDGKLVTGVNPASAHSTAQRAIDALN
The following text describes a protein:
Function:
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Required for meiosis, but plays no role in conjugation.
Miscellaneous:
MISCELLANEOUS: There are three genetic loci for mating type genes in S.pombe, mat1, mat2-P and mat3-M. Cell type is determined by the alternate allele present in mat1, either P (plus) in a h+ or M (minus) in a h- cell. Mat2-P and mat3-M serve as donor of information that is transposed to mat1 during a switch of mating type.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSAEDLFTIQILCDQIELKLASIVINSNIKLQLKRKKKTQQL
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MEALTCDEDDYYTSLLLMEDSQIFEKKNTFFSDNDGDEDFAQKLQLQETLISSFTTSSQKPQRNTSSIEVGESSSSSKKRRRLKEEKESSSPSKKRRRSKEEGESPRRSSSTSSRFVCEICTEKKKKYKIFPFLNHNCSHKFCTECISKYLTTKLKRGKSPSIACPGPDCEGILGIEECVGGVVPKEVVTLWDEVICESVIIPSSQRFYCPYKNCSALMMNDSDTRNTMREAECPSCRRLFCVKCNVPWHSGFECGDFSRMRESESEREDLKLHALAKKKKWRRCRRCKFFVERNKGCLHMTCRLVNFVLYYIQNCYTVHFYYCDNLGL
The following text describes a protein:
Function:
Transcriptional activator of the bioluminescence operon. Binds to the OHHL autoinducer.
Sequence:
MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILDNYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLITGFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSNNDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILTGAIDCPYFKN
The following text describes a protein:
Function:
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
Sequence:
MLEEINYDTKLFGLIGKNIKYTLSPYIHNFSFRTLGINAVYLVFDLDEMKFKRSISGILEIAEGLNVTIPYKDEVMKYLDNTDTHSTRIQAVNTIYKKSGYNTDYLAIKNLVRKKIKNVSGYECYIYGAGGAAKAAAFALSELGCSSISIVNRTKSRAYELAELLNKNGYNASIKENCNITNNILIVNSTPNSSVVPEDCVKKSDLVIEFVYRPVETELIKNAKKYGIQYINGLEILVNQAVEAEKIWFNKSVADEKIIEYLYARELVW
The following text describes a protein:
Function:
Putative transporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MATRLSDLFGNSRIIAGLLVNLLSSICIVFINKWIYVHYGFPNMTLTLIHFVMTWLGLFICQKMDIFAPKSLRPSKILLLALSFCGFVVFTNLSLQSNTIGTYQLAKVMTTPVIIAIQTMYYRKTFSTKIKLTLVPITLGVILNSYYDVRFNLMGMIFATLGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAFLLVLVPFFEPLTGDGGIFGPWSFLALFMVLLSGVIAFLVNLSIYWIIGNTSPVTYNMFGHFKFCITLLGGYVLFQDPLSLNQGLGILCTLTGILAYTHFKLAEQEEGKSRLTQRP
The following text describes a protein:
Function:
Important for normal assembly of actin bundles during bristle formation.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Colocalizes with actin filaments.
Sequence:
MGNGYFRTSQTSSSSRQREKRGKDSYSYQHNYVDRVRLEDTTGGHYHNNQHQQTTHDPRCPQLRAAGWRHTHKSVSHLDLATSCHDAAGTGLGRHSQQLHHHHSNQVNQHHHQQQQSHHHLQHANLHSHHPHAQPHWTQCRVGGAGSGNGQLRNARSLDYTQLEREENALDIAEFYWRFDAEAPLDQVDSYAVLPINDNFEPSAATSTAVGSKETTTTVANKANGSATTNATTAAANALLDILGSESCSLRRSRSLAVIREETFSDLQIGSANSSRRRSQLIPRARLVNRGFFRESPRSRHKFQFKQFKKKPPAKLLRLNGKPNQATLVGEQPADQPTADDTQSQRSNSATCDSHQQQQQQQHQPQQQHQQQQHRLSGESRDFDVYYDNLKRLDALALNLSEQLHPWHNDKSDLESLNSDYFKNSLHQNHLDQQQPSSLEFEALEQVAASLLKERPRIYQSRRQQQKRNNHHSNCLQRHLDTGGESCPEHSQSSVFPETTTSNSDDQTDSPSLSEQEYDLTHIEEIYQQGNNGEESYEIISLTTTTRTRFESSEEGEEEQTGEEVVDSLTTPTEPQTSDSESTLRQNHNEQLDKLIAYDSVYLSSEDSSDCTLVGESCESFEQRTFTSCGESGELETRSLLHISIEDTVYEPQAKQHKKATNQEDQPAPLLTTTAKVEAQIFTQVLKVEHTPKPNILAVVEKRKLKQEEVKHQPPELKRQATDSFVVTANKSNLAENQYHSLPDVNIGVSLKVCESIDKELRSSYNQQRQQQRKEAKKEQQVTRAETYDSIRRFGRAHQKARQREYQEREREREKEASAALQEKDKEREREKPKINKEFSAQERQIEVKETTKSQDIIKEKEQVSRKEEAEDDEEEEPLPPPPPPLTEESQQEDTVADVEEEDNLSVSISQPEQPKEAPVIEVANFSKLIERRAQEIRERQEQIKPSFQIIVTDAQNNIIQKEAIQENKETSQRIEPKPSPKTNSNSSSTCNLVQRPLRRSVSSSSGKPLEHRILSTGAPIYKARPVRVLPSSSSDSSFSRGKMSRPQILHVVDGRGGVAGGGAGGTLRRRSSARSIASTISSPGGEVANEYLQKVDAVRCYWNKLAGNEPETLKTEQPAKETQPGIHFQLGGETTTQGTDKSAVGNDFCSMMPHPSIEIVELGEGAQKATIVKAAPEREEDPDEDQDQFDHIRYKVLKSQQLIRNNFLSTRNKKEAQFDGLIQYLQEYSFQELLSNNNVVIVEPVRTKIERPLQVGINSGSTTTPTTVPPPKPPRVVNASASQPRKTRQKQTGGAAAKRHFFYQPVRVNRELYEDELPDPDTVRNVRRFFEQNVLPTPGQGLLVQSQQKFGGSACQLSPKSRRARGYRYLTIDTSYGGAEEQPKGMEMLEEHKAKHWDNASLSSGISSGVLSSPCGEYHHQESPVMACKDVHVQDVVRRHNSNAANAKARAKFASRRTWCMGAGGPGANESLYRQIYENNLGNSEQQENGEHLEEEDDEQDDQYEDDVEQDMCENYYVSNDVLAKIRECGSTVTYYGGRVLDKTATSTAAPSTKTTQPMTGSATRSRIRQIEACNVCLPSERCEHRLQTKQAAAKQQQDSYQGIKFKLVKSNSCSSRLELAGTGEDEVTADSEVVRKMVHHFEANQTTASNDVQVTINSQSQITSTKKEPEEDVPRRQVTVNNHINVLGDTMPQASQEKAENFNGRPEENGYGAVETVPTYESQAMNIRLDATENKNILQTAAATAAANKVCRNKNVDLAYTLVKTTTNSPKGKPIEAPRQKIGKQLREVEENVEKAAVTKATIKLTKGAPSQIIVPVDIHSQASIVAHTAPIPERRLSNASSSNSVVDKTVVRHYVANDKSIYERRKYDEIEFEEFEVYDPSKEPPPQVEEGTDKIPTDAELYDSLDDKM
The following text describes a protein:
Function:
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
Subcellular Localization:
Cytoplasm.
Sequence:
MAGQPEKKPQSVYDFSLKDATGNDVDLSIFKGKLNILIIICLVVYSGMTNSNYTELNQLYEKYKDQGLEILAFPCNQFGEEEPGTNDQILNFVCTRFKSDFPIFDKIEVNGENASPLYKFLKSGKWGIFGDDIQWNFAKFLVDKNGQVVDRYYPTTSPLTIEYHIPTTTTMAGQPEKKPESVYDFTLKDAKGNDVDLSTYKGKVLLIVNVAGLTDSNYKDLNHLHEKYKDQGLEILAFPCNQFGAQEPGSNDEIVEFACTRFKSEFPIFDKIEVNGENTSPLYKFLKSAKWGLLGDNIQWNFAKFLVDKNGQVSDRYYPTTSPLSMESVYLR
The following text describes a protein:
Function:
Facilitates initiation of meiotic recombination and DNA double-strand break (DSB) formation at DSB hotspot sites by enhancing the interaction between rec10 and rec15.
Subcellular Localization:
Nucleus. Chromosome. Note=Predominantly localizes to linear elements (LinEs) on meiotic chromosomes, the S.pombe equivalents of synaptonemal complexes. A proportion also localizes to DNA double-strand break (DSB) hotspots.
Sequence:
MNSYKEEILQTKSDFTLKNLIFFAISTLCYKRALFNENCYKKVNFEIEHFKGADFDCQLKPTVVSLQAGVDKEADSFLEMMKTYIFSLVSMKVPFTVYLIISSQCKSILEDDAVEKEIFSFTINPGSEEKICCESFVSYQRSERFVIKLFLSGNVKTECKDEEKVVQIITKMERFQLSKGEATKAGVFLNTVETKDCMSWLNRGEFKDIVSFYESNNGIAISHCSHAFVPISTEKIMINKESSLFDSQEKIDSQLEKFLQPLKYDEIGSTQILDEQSVEKSLSQGKCEKMQNESRGLREIKNNNPCEEVKKSNWLKKNISGSDKVDKAEKKKALLNCECGDSTEDSEMFQCERCDGWVHCACYGFESDSDPRQPNQLLCYTCLLVDSESSLYDRMTMLVAYRRAIRCIWASEYQGFQKLAARLNCSYADAKRIEERLVNENIIYKEKKRKWIYFTNKSPEMVSYLREKYFTPSRWISHLNFQNYRQENQRVNMRSFLRPERMEVIERPKKVSKTSNTKETDTMKPLRI
The following text describes a protein:
Function:
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular Localization:
Nucleus.
Sequence:
MSDYDSDDAANIQGAPNTEKRRRLRADYRSAIAQAEENMQEVLNGKTKIDLHSELRQVNELFLDVKATQDAALDSKALLLIAEMSSYKVQRLNFGGGSFTLEDFVSKVAARLGGSEQSAVRNHDDASVHSLNSDNLKWDALAETIARISTRVCIPGFMYGAIAVEPKQREFKRRTAKLVKDGSKLRQPEQLAEEDIVQQENETSSNVQLIYRCLEQVQPVNFFKFFINPDSFSQSVENLFYLSFLVHDGLARLEDKNGKLLLSTEVPPTESDLQRGVTKLQHILSLDMKTWKDAIETFDITKPIIPTRVSHSVKDNGKWYG
The following text describes a protein:
Function:
Substrate-selective channel for a variety of different sugars. Could potentially facilitate the diffusion of diverse compounds, dependent on the presence of a hydroxyl group, but is presumably restricted to carbohydrates. Involved in the transport of glucose, mannitol, fructose and glycerol (sugars able to support the growth of P.aeruginosa). Facilitates glucose diffusion across the outer membrane.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MYKNKKTRPAARTVGCLFALGALGLGSAAHAAEAFSPNSKWMLGDWGGKRTELLEKGYDFKLEYVGEAAANLDGGYDDDKTGRYTDQFALGVHMDLEKILGWKATEFQFTVTERNGKNLSNDRIGDPRAGHISSVQEVWGRGQTWRLTQLWLKQQYFDGALDVKFGRFGEGEDFNSFPCDFQNLAFCGSQVGNWAGSIWYNWPVSQWALRVKYNFAPDWYVQVGAYEQNPSNLETGNGFKMSGSGTKGALLPVELIWQPKVGAEQLPGEYRLGYYYSTAKADDVYDDVDGQPQGLTGNDFKSRGSKHGWWVVAQQQVTSHNGDASRGLSLFANLTVHDKATNVVDNYQQLGVVYKGPFDARPKDDIGLGIARIHVNDDVKKRQRLVNQVNGIDDYDNPLYQPLQDTEYNAELYYGVHVTDWLTVRPNLQYIKQPGGVDEVDNALVAGIKIQTVF
The following text describes a protein:
Function:
Receptor for neuropeptide Y and peptide YY.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNISHFLGLLFPGAPQGQNRSKAKGIPYNFSDHCQDSIDPMVFVVTSYSIETIVGVLGNLCLICVTIRQKEKANVTNLLIANLAFSDFLMCLICQPLTAIYTIMDYWVFGEVLCKISAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSVSQAYLGIVVIWLIACFLSLPFLANSILQNVFHKNHSKAVEFLADKVVCTESWPLEHHRIIYTTFLLLFQYCIPLAFILVCYVRIYQRLRKRGRVFHKGAYSSRAWQMKRINGILAAMVVAFAVLWLPLHVFNSLEDWYHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEVKALVLTCQQSIPVEESEHLPLSTVQTEISKGSLRLSGRSNPI
The following text describes a protein:
Function:
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSYQQQQCKQPCQPPPVCPAPKCPEPCPPPKCPEPCPPSKCPQSCPPQQCQQKCPPVTPSPPCQPKCPPKSK
The following text describes a protein:
Function:
Probable heavy-metal-binding protein (By similarity). Required for female gametophyte development and function.
Sequence:
MVTGNFNLEKLLKNLKKKTGKKAEILTMNEKVEKEDVVQNEANEQETVTKKNEEGDIVDKKDETPEVEEKIDKPETSTRKLEIHIAFLSEKYEADIGKVISKFEGVKTCKVDVENKKVVITGDFDEEKLWKELEEKMRKRIVKMEKEKKDDEPITKDEENEIDRGVYMNPSSDDEKEMARWMMFSDENPNACSIS
The following text describes a protein:
Function:
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MAMNRNERVVLGMMALRLLPLLVVLAAAEVSSHVSPAVPSLTCTNDYINNISCEWRSSEAYSNTSCRVHLVRRRKQFQCDLIASDEPTVCSCSIQVTKNANTQSFTSVDECDIEVRCGDSKEPAAKIKDFKPSENVRMRPPDAPIIVNSTVSWGAGERVSRLIYEYEFQIKYKRADQTWEEAESRVVVNKENSTQLNENMLEKGALYQVKVRVRPAAKGPLKGVWSHWSPVSEWTSTVGIVKPAVKRAYNPGSNDKEIMDITLAVAIPAVIAVFLTICICGIWSPKWSYKCLHVPDPSKYFDPLNSVHGGNFQKWLSPTFSPESFDTLNSEPVSPVEVFEAKDTTSLFKKAYPSLQEHWDSSGQSSCFSNMGYFYSKHPSSYEIESCSVYFSYQPAEFDSEEGGSGDGGDTPIQTSSSYERLDPSSREQSDPEHPDSGCGMERGEEGDQETEDGREGGEEANPSLLGPGCPPPPFNPAFLPAFPPPFRLPGSHPQLLAHPPFPFPLPGFDFRAFGSGQALDSALSKASSALIQPSGGGYLSVKDVQNRYCNKSI
The following text describes a protein:
Function:
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Note=Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli.
Sequence:
MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLLKDIKFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKPNYKLDHIVKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFLHYVIAARALRKVFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQLLNLHYPPKLESQAQTEAKTSEDTYALDSESSMEKLAALGASLVRMVVPVEEEAEMDEFPADGEMTVQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFVIRSFGGDVSWDKSLCIGATYDVTDSCVTHQIVDRPGQQTPVLGRYYVQPQWVFDCVNARLLLPVADYFPGVQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEHPGNTDESEEEDEEGDDGDEGGENEEEEEEDAEAGSEKEEEAHLTALEEQRMEEKKPRVMAGTVKLQDKQRLAQEEENEAKRLAIMMMKKREKYLYNKIMFGKRRKIREVSPCHLPETPGVATRCGCTGELWSQLTLLCADSRPFLSPPCPQSPSRPFLSLSLRLPVWLDP
The following text describes a protein:
Function:
Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).
Miscellaneous:
MISCELLANEOUS: The amino acids 62-79 are situated in the membrane and are important for channel structure and properties.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Domain:
The cytoplasmic C-terminus is involved in the gating mechanism.
Sequence:
MPPMLSGLLARLVKLLLGRHGSALHWRAAGAATVLLVIVLLAGSYLAVLAERGAPGAQLITYPRALWWSVETATTVGYGDLYPVTLWGRLVAVVVMVAGITSFGLVTAALATWFVGREQERRGHFVRHSEKAAEEAYTRTTRALHERFDRLERMLDDNRR
The following text describes a protein:
Function:
Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
Sequence:
MEFLRLNLLAPLLLSLSLLLPLTLAVDVTYCDKNADYDVTVQGVEISPYPVVRGSPATFSISANTGETITGGKLVIDVSYFGWHIHSETHDLCEESSCPVSSGDFVISHTQVLPGFTPPGTYNLKMKLVDKKNKELTCIGFDFSIGFVSPVADS
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MEVAMSKDLQQEANLAKKRYIDLCRQGRIFDARNRIIGGDTQAWDFQVRDQKIKEITDKARHEAFAAEMKHNDKVMCMAHDREQRHRKQLCRAINDFQQNFQKPETRREFDLSDPLALQKELPARISDNDMRNTISGMQKFMGEDLNFQERRRFQKEQSREWFLQQHGEREKARADHLLAEHLHTQTRLKFDETARELMKLEGSTRKEVCAAVKAFNKNQVVELTERKRQEKQQEQEDNMTEITNLLHGDLLSENPRPVASSFGSHRVVLDRWKGMNREQLEEIWFTQKRQIQEKLRLQEEERQHSMDWDLRRIRKAHASLLHERQQQRLLREQRRALDCSNLNLARQQYLQKKQMNTASSSQPTEDYFSQFNTRSR
The following text describes a protein:
Function:
Required for the transposition of the insertion element.
Sequence:
MALPQSALSELLDAFRTGDGVDLIRDAVRLVLQELSELEATERIGAARYERSDTRVTDRNGARSRVLSTQAGDVELRIPKLRKGSFFPAILEPRRRIDQALYAVVMEAYVHGISTRAVDDLVEAMGVETGISKSEVSRICAGLDEIVGAFRTRTLGHIEFPYVYLDATYLNVRNGTGQVVSMAVIVASGIAADGSREILGLDVGDSEDETFWRGFLTSLKGRGLGGVRLVISDQHAGLVKALKRCFQGAGHQRCRVHFARNLLAHVPKDKADMVASMFRMIFSAPDAEAVHATWEGVRDRLAASFPKIGPLMDDARAEVLAFTAFPKAHWQKIWSTNPLERINKEIKRRSRVVGIFPNPAAVIRLVGAVLADMHDEWQASERRYLSEASMALLYPDSDNAVVAAISGGQ
The following text describes a protein:
Function:
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
Subcellular Localization:
Early endosome membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane. Cytoplasmic granule. Recycling endosome membrane; Single-pass type IV membrane protein.
Sequence:
MATSAASSEHFEKLHEIFRGLHEDLRGVPERLLGMAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRTYRKDLAKLHREVRSTPLTATPGARGDMKYGTYAVENEHMNRLQSQRALLLQGTDSLNRATQSIERSHRIAAETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSIVILLELAILGGLVYYKFLRRH
The following text describes a protein:
Function:
Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MDAVKRVQEFELTWVVYDPTDPLGVVLALFTLSPIFLVITYLTIVASQRDLDSISMLVGQLVSVVFNKVLKKFINQPRPEGAYMTGPGMPSAHSQFMGFFAAYVVIYTWKRMNSRRRLEQWFTIFSVIMMAVLTCYSRIHLNYHSTDQVVVGAVFGVLTGVVWYMLVSSVSPWLFPRVAESSLAKFFYIRDISHISDLTVYQHEICRSKAPVASPSKKSQ
The following text describes a protein:
Function:
Acts as a co-chaperone and mediates the association of the chaperones HSP70 and HSP90 probably facilitating substrate transfer from HSP70 to HSP90. Stimulates HSP70 ATPase activity and, in contrast, inhibits HSP90 ATPase activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MAAEQAKDRGNRAFSAGLYADAVACFSEALAVAPNAPNAHVFYSNRSAAQLKLRKADEALKDADQCVARQPSWPKGYSRRGSALYALGRYADAYRAYQDGLKLEASNAGLLEGLRAVEAKLSTQRAGTSHGAASASHAPPPATTLRTFLLGSKRSMFQLYQFVLRSLMLLCFVNFWVPVLLSGYSAYANFFKLALVNHASYLAFTHGVPKWNAAYAQRLLLDPAAQAFFFCLVFWVSAPHGMALMPVFLLEMVHYFSFLQSLLQVLGLADSSVVMLVTSKALVPLTALIISDPSFPALATRAKWAKLYTRMPQVAANLDVAIGVALVLEMVTPSRNFLLLVLYWQVLRVRYMISPQLQEAFRSLHATILTLVNHPRCPAVIATVYGKIHAFAVKMGDTAQQQQQAASGAGGLASRCNIM