lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Sequence:
MTKKRRNNGRAKKGRGHVQPIRCTNLARCVPKDKAIKKFVS
The following text describes a protein:
Function:
Flavonol 7-O-rhamnosyltransferase that catalyzes the transfer of rhamnose from UDP-rhamnose to the 7-OH position of 3-O-glycosylated flavonols, such as kaempferol 3-O-rhamnoside, kaempferol 3-O-glucoside, quercetin 3-O-glucoside, quercetin 3-O-galactoside, quercetin 3-O-rhamnoside and isorhamnetin 3-O-glucoside. Is able to glycosylate the flavonols quercetin and kaempferol to yield quercetin 7-O-rhamnoside and kaempferol 7-O-rhamnoside. Shows a strict specificity for UDP-rhamnose as sugar donor. Does not act on 3-O-glycosylated anthocyanins. The accumulation of kaempferol 3-O-rhamnoside-7-O-rhamnoside inhibits basipetal auxin transport, which influences auxin distribution and plant organ development.
Sequence:
MTTTTTKKPHVLVIPFPQSGHMVPHLDLTHQILLRGATVTVLVTPKNSSYLDALRSLHSPEHFKTLILPFPSHPCIPSGVESLQQLPLEAIVHMFDALSRLHDPLVDFLSRQPPSDLPDAILGSSFLSPWINKVADAFSIKSISFLPINAHSISVMWAQEDRSFFNDLETATTESYGLVINSFYDLEPEFVETVKTRFLNHHRIWTVGPLLPFKAGVDRGGQSSIPPAKVSAWLDSCPEDNSVVYVGFGSQIRLTAEQTAALAAALEKSSVRFIWAVRDAAKKVNSSDNSVEEDVIPAGFEERVKEKGLVIRGWAPQTMILEHRAVGSYLTHLGWGSVLEGMVGGVMLLAWPMQADHFFNTTLIVDKLRAAVRVGENRDSVPDSDKLARILAESAREDLPERVTLMKLREKAMEAIKEGGSSYKNLDELVAEMCL
The following text describes a protein:
Function:
Catalyzes the oxidative deamination of D-amino acids with broad substrate specificity. Enables the organism to utilize D-amino acids as a source of nutrients. Enables the organism to utilize D-alanine as a source of nitrogen.
Subcellular Localization:
Peroxisome.
Sequence:
MTDSKYVIIGAGISGLYTAWSLIDKGTGPSDIKVVAEFLPGDQSTLYTSPWAGGNFSLITSTDERSMKFDKFTYTNLHRIQELLGGPECGLDMLPSTEMFEQELDHAKLDSISQYLKEYRPMTKEEMPEGVVSGVKFLTWNFNCPLFLANFQKHLAAIGVTFERSKIDHISSVFSPSVDAVFNCTGIGAASLGGVKDENVFPTRGQVVVVRAPHIRENRFRWRPDSDTYVIPRPFSDGSIVMGGFFQEGNWSGNTYGYETEDILKRGLELYPEIGKRNELKIIREAAGLRPSRKGGVRIEVEHFDQVNGKDRYIVHNYGASGYGYQSGLGMANEATDMYFEAAK
The following text describes a protein:
Function:
Catalyzes the last step of the phosphorylated serine biosynthetic pathway, i.e. dephosphorylation of O-phospho-L-serine to form L-serine. To a lesser extent, is also able to dephosphorylate phosphothreonine, phosphoethanolamine, and histidinol phosphate in vitro.
Miscellaneous:
MISCELLANEOUS: ysaA complements E.coli serB and vice versa.
Sequence:
MKAVFFDLDDTLLWDEKSVRTTFAETCLQAEKKYGLAPEEFEAAVREAARELYMSYETYPYTVMIGINPFEGLWSNFSEPISEGFQKLNKIVPEYRRNAWTNGLKALGIDDPAYGEYLGEFFAAERRKRPFVYDETFAVLDQLKGKYELLLLTNGDPSLQKEKLAGVPELAPYFNEIVISGAFGKGKPDVSIFEHCLKLMNIEKDDAIMVGDNLNTDILGASRAGIKTVWINRTDKKNETDVKPDYIISSLHDLFPILEK
The following text describes a protein:
Function:
In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.
Sequence:
MYLKFDKKADKLIVTMAGELDHHSAEEVRNVIDDRLDRENLNKLILDFSKVNFMDSSGIGVVIGRYKKLSLRDGKVCLTNVQEAVRRVFELSGMFKIVNLYDSVDEAVENL
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC).
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane.
Sequence:
MSEIFSTGDQSSGSLEDSNDEVRRKNETAFKYSQLFHTTLCEKLYQELCALAIGEFDIPEGQISPVMWTRLHEIYSEVEMQTRKLPNGAKYSIDSQKYANEAVQIASILSIYTALAHEYDETLEVSLLSKLVVDDVEFRRLYALLLWSEKAISEQQYESGLGDKVRKIESTKSNRINSIMILKRPTFSAGAPKDASLDPDAPGTKEDQTLEQMAYTTFFQLVRCGETTKAANLAIDLGMSAIGAQLQLHSMLRNPLDVPLKVSSQNFGEVKRARRAKYYEMTQRLIEESNGSEDNAYWTLVSALRGNIAPMLKASKNVIEKVWAYANSAVLARLLLAEGAMDQETVATLFNVPLTAKSLLEELRTVSYIFSILINFSLFKEYDGSKEVYILLRVIDDMLNDDIEDLFKFANETVGEYVPDDKNCEVNVLALDIFFHLVAVAYASGFESNDDGNAVIVLGFDDLRVRSGSTSHKRMAAFYSRFLPEDMKIPEIVETMKMVESEKEREIFAESLKQSDINFGRCACTLIEQIRKDDEAKIVSLEAQIDHWNWLLVGGEETALAALEECNRLLRKIMLKKPMDEPVVRQIIRRAIQMELPKTLSQAVVNGTTLLSLIKDGTLYEQEKGSQLAIDKVEHAAYEFYALCSILDVNNFIITIALKLNLMVKYSPITDDELAAMGGGKRLDNVNALDWEASLRVRARAEQTFREDLCKKTAADHNTRLGMVHQHFDTVLPIFRGLVQNIGIRPEFFLSPRTNSDPMRDHRREIQMLRNHFITQFFLTLAEAAAKLNETTRFQEVVTSFNDDFGIDQSLVTTIKGYYAKVNIKLD
The following text describes a protein:
Function:
DNA-binding protein that binds to the 5'-CAAG-3' core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear.
Subcellular Localization:
Nucleus.
Sequence:
MAQDRECLCSAGFQRGDYTQGNTDRSTAAANSRPPAGQRGAEEPSSGGAGTPPPAAVLPTMPDEATENAGSTSARVSSFFIEDLLGTEGGGGTRRAAAGGGGGRGAPRCGPHSPLRLGASGCPLRDAAVGWYRRAFLGCASPDTSDRDSPELPEDTERAGGGGRAAARGPAGGRQSSGGREEEEERGEEAGEAEQRAAGRKKKTRTVFSRSQVFQLESTFDVKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAADLEAANLSHAAQRIVRVPILYHENSPASALGFGLPHMSPPLVGFSGGVSYPLGTFPAASLPFLRSQMTGLV
The following text describes a protein:
Function:
Catalyzes specifically the mono-ADP-ribosylation of GcvH-L (SAV0324). This activity is dependent on prior lipoylation of the target protein. May be involved in the modulation of the response to host-derived oxidative stress. In contrast to other sirtuin classes, lacks protein deacylase activity, being unable to catalyze delipoylation, debiotinylation, deacetylation and desuccinylation of proteins.
Miscellaneous:
MISCELLANEOUS: The SirTM-mediated ADP-ribosylation can be specifically reversed by the Macro domain-containing protein encoded by the same operon (SAV0325).
Sequence:
MMQSSKWNAMSLLMDEKTKQAEVLRTAIDEADAIVIGIGAGMSASDGFTYVGERFTENFPDFIEKYRFFDMLQASLHPYGSWQEYWAFESRFITLNYLDQPVGQSYLALKSLVEGKQYHIITTNADNAFDAAEYDMTHVFHIQGEYILQQCSQHCHAQTYRNDDLIRKMVVAQQDMLIPWEMIPRCPKCDAPMEVNKRKAEVGMVEDAEFHAQLQRYNAFLEQHQDDKVLYLEIGIGYTTPQFVKHPFQRMTRKNENAIYMTMNKKAYRIPNSIQERTIHLTEDISTLITTALRNDSTTQNNNIGETEDVLNRTD
The following text describes a protein:
Function:
Probable RNA-binding protein. Involved in the regular timing (plastochron) of lateral organs formation. May regulate the rate of leaf initiation and the duration of vegetative phase. Seems to be redundant to the function of PLASTOCHRON1, but to act in an independent pathway.
Miscellaneous:
MISCELLANEOUS: Plastochron is defined as the time interval between leaf initiation events.
Sequence:
MEEGGGSGVGGMQGAASNLLDAGAQAFYPAVGAPFPFQQLPHQLYCPQPPPPPYQVMPVPPPPPPVGLPVPPLPATMAPQPGYCVPAAATVVDGPASRAVVLSLVPPHAPEDEIARAMAPFGAVRAVDASAVASEGVATVYFFDLRSAEHAVTGVREQHIRQQCRLGQLYAAAAAAAASSPTWPPPAWDWPHDDNRGLVLGQAVWAHFAAASTVPDDGASRGSLVVLNSLPAMSVFELREIFQAYGDVKDVRESALRPSNKFVEFFDTRDADRALHELNGKELFGRRLVVEYTRPSLPGPRRRGHVSHQPLAPTPPRLQAAWRPAPAPSQSAQPSSSGSGKAREGVVLLRRSSGKGSSGSQSKGGGNAGHERKSKGGKSAAAACSTAASASSSTATAPSKQSQKGGGGGGGRGGSWRGQKSGWEARFLFKEPEAAAAAAGDAAASETHEPASCKDTRTTVMIRNIPNKYSQKLLLNMLDNHCILSNQQIEASCEDEAQPFSSYDFLYLPIDFNNKCNVGYGFVNLTSPEAAVRLYKAFHKQPWEVFNSRKICQVTYARVQGLDALKEHFKNSKFPCDSDEYLPVVFSPPRDGKLLTEPVPLVGRSPAPSSASGASSPPKSCAASVDPLAQELMTAPSSSGDGASSASSSNAHADEDDVHGETGGDRGDDAGLDLELQRLGYTD
The following text describes a protein:
Function:
Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSHTVIDELKRNQILELLEQGKRVDGRALDESREVSIETNAIPKANGSARVRLGDTEVVCGVKIQPDRPFPDTGDKGLFICTAELLPLSHPTVETGPPGPEVIELARVVDRGIRESHMIDVSQLVIEKDKSVIGVFADNVVVDYDGNLFDACSYAATAALLSSKSPKWNWVDDAPALVEGEEVDVPITTIPVSVTMGKIGNHIIVDPNGDEWASMDARITITSDSDGNICALQKGGDDGFTQDEIVQCGEISVRVGAKIREKLKAAQQGGQ
The following text describes a protein:
Function:
Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MVSVSPAAPQSLNAAAPAPLRILLDGIDRLGRLDGWIGGGCLLTLTLLMLCEVATRFLSNFLPFFPPTISIAWEYSSYLMAASFTFGAAMTLRVGGHIRVVLLLKNVPAPFQRAIEILSAAAGFAFMAFLTSAMAKFAYGAYVRGQVSTSSDTPLWFPEAVVTFGMLLLTLQFLARAIQATLGLPLEDHRMKASPVE
The following text describes a protein:
Function:
Probable metalloprotease.
Sequence:
MLNLEKIEKLLEVGDYADIRINFGESNTITLKDGKIEEISSGFGNGVAVRVLYKNGWGFVTSNIVSEEEIEKLINKAYKMAKISNEYSEKEIILKDYKAIIDNYKMIGKINPTDVDIEEKKEIIIDTYKNMTDEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNCVAKENGNLQYGAERTGGFGFEKIKDNYLNLALEAKNRALRLLKAKPCPKGKFKVILDPELAGVFIHEAVGHASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYKYDDEGVEGKKTVIIENGILKTYLHSRETAGRMDAELTGNGRAEGLNKPIVRMSNTFIKPGDWSFEELLEDTKEGIFLKGSRGGQVDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGEILDILFKVDAVTKDFELSVGYCGKDGQSVPVGDGGGCVRTIATVS
The following text describes a protein:
Function:
Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway.
Sequence:
MDGDEASLVANFCAITNSTPEKAQEYLSVADGDLSTAITLFFESGGVTDVQSSYIEAPSQTEPVEEIRAPIAPTREVLVDPLADMSAGTSIMGNNFGFGGFPRMNRRQRRRMGIFDQSPSQIPFPSSNTEDSSEESDSSSRASRLAKLFRPPYDIISNLSLDEARIEASSQKRWILVNLQTSTSFECQVLNRDLWKDESVKEVIRAHFLFLQLLDDEEPGMEFKRFYPVRSTPHIAILDPRTGERVKEWSKSFTPADFVIALNDFLEGCTLDETSGRKNPLGAKSQKPVEAMSEDEQMHKAIAASLGNGNSTTESQGESSSQQAESHGVADDTVHKIDSAECDAEEPSPGPNVTRIQIRMPNGARFIRRFSLTDPVSKVYAYVKGVAEGADKQPFSLTFQRKSLWTSLDSTIKEAGIQNTALQFEFQ
The following text describes a protein:
Function:
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
Sequence:
MSISYTGQLPTTSPLSLTQLITSDRYQQVIENADAARARVREQLKHAKKTGATEANGDIMPVIKALEEYMPHITSIVDNEGVFRFTSQIITCWRLPFQSQSSMANKTPLHGLSFEYIMVLFTYALALATLANQYVARDKEDRWKHASAYISKARGVVDYLRQCRSFQIICNEPPASVPRDLSSATMSALSHMLCGASHMLILYKCDAETYLDGGAPSAGANSGGFSSSLLLRTAIFARDQFETASALLGEPVSKRKLVTSLVKEKSSKFSLSKKLHLRKDDGSPSLAPVSSFESNRDLSSTSSGTLDSLLSWLSRARGVAEGFVFKHMAIQAYENNQIGKAVGAAYAAILQLEDVKIPQKSALYIPVTHLKETLNRHHADYKADNDRLSFEPVPSPSELAQEWPSGRQVISAQKWTPQTSLDLGEDTSSSAPKYSGQGSYY
The following text describes a protein:
Function:
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
Subcellular Localization:
Cytoplasm. Endosome.
Sequence:
MEQSLFFLSAEMTAMKAFNEKTQSIYQNMQFLDKKLKMKVPKLSLAITTHRLIFTNHTNIDQLNVNDVKFVYFVIPLQHVKSIQSKTGFLSSKIDHINLETNLGEVAIFGDNLEGPLLLIKGSIEKKEWLQKQEQQQTSSVYCGMKSEIMKKEKQTQQTIDTVQSTFKGGFEELFKNATELKEVSQYIKQNIKKGENNEIDEILSKIGQSRLDKSEDLFYEKLAEQVYKLCAELFPKMGGIISLLDVYYYFNKRRNSSLVSPEEILKAGLQFQKLNYQAKVERYDGISVIESTQYNSDKDYENTLGKHISYEIGLTAEQLAKKLGISVMICKIKLKNAINQGKVCVDNRIEGTRYFKNLIINI
The following text describes a protein:
Function:
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
Sequence:
MYDYEWYVDLVAEDQLHCYKIEEVIVDLVSPYQRIQIIKNPTYGKCLIIDGKMQSTEKDEFIYHEVLIHPALILHPNPQKVLVIGAGEGATLRELLKYENVNITAIEIDPNMVDFAEKYLWEWHQGAFRNERVKLIFEDGWNFVRDTCEKFDIVVLDLPEPYPDTPAYRLYTEEFYKMIYHILNPSGIVVTQAETVQLGQEYKHFNIKKNFSAVFKSSHSYQTFIPSFDGSWGFLIGSRDELNPFKPVEVINELIGKKIKGELKYYDGETHNHLFHLPKYLRKLI
The following text describes a protein:
Function:
Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEWNRETLVFLSQCFLNTLSPIPEPRRTAERALSDAADQANYGLAVLRLVAEPAIDEQTRHAAAVNFKNHLRSRWHPAGDSGISPIVDSEKEQIKTLIVSLMLSASPRIQSQLSEALTVIGKHDFPKAWPALLPELIANLQNAALAGDYVSVNGILGTASSIFKKFSYEYRTDALFVDLKYCLDNFAAPLTEIFLKTSSLIDSAASSGGSPPILKPLFESQRLCCTIFYSLNFQDLPEFFEDHMKEWMGEFKKYLSSNYPALESTEEGLTLVDDLRAAICENINHYIEKNEEEFQGFLNEFASVVWTLLRDVSKSPSRDQLATTAIKFLTSVSTSVHHALFAGDNVIKEICQSIVIPNVSLRVEDEEIFEMNYIEFIRRDMEGSDVDTRRRIACELLKGLATNYKTQVTEVVSLEIQRLLSSFSANPSANWKDKDCAIYLVVSLSTKKAGGASVSTDLIDVQNFFANIILPELQSRDVNSFPMLKAGSLKFLTMFRSHIPKPFAMQLFPELVRFLKAESNVVHSYAASCIEKLLLVKEEGARGNRYAAGDLSPFLLQLMTNLFDALKFPESEENQYLMKCIMRVLGVADISAEVAGPCIGGLTSILSEVCKNPKNPIFNHYLFESVAVLVRRACERDISLISAFETSLFPSLQMILANDITEFLPYGFQLLAQLVELNRPTLSPNYMQIFLLLLSPESWKRSGNVPALVRLLQAFLQKAPHEVTQENRLSQVLGIFEKLVASPSTDEQGFYILNTIIENLDYSVIAPYMKGVWSALFTRVQNKKTVKFQKSLVIFMSLFLVKHGQAYLVETMNTVQPNIITAIVEHFWIPNLKLIMGSMEVKLTAVAATRLICETPALLDPSAAKLWGKMLDSIVTLVSRPEQERVLDEPEMPEISENVGYTAAFVKLHNAGKKEEDPLKDIKDPKQFLVASVSRLSSASPGRYPQIIGENLEQANQTALIQLCNAYNCGIA
The following text describes a protein:
Function:
Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions.
Subcellular Localization:
Nucleus.
Sequence:
MMFSSQLDAFSPSQFTSSQNAAADSTTPSKFRGASSTTPLTVKQIADAQLSGSGDKGAPFVVDGVEIANIRLVGMVNGKAERATDVSFTLDDGTGRLDFIRWVNDATDSAETAAIQNGMYVAVIGTLKGLQDKKHATAFSVRPITDYNEVTLHFIQCVRIHIENTKSKVGSPAKTNSAIGTSLSNSLSEATTPTSLKSQAPVTSGTDGSGTDDLHTQVLKILCEPANAESEHGVHIDEITKRFKLPAEKIKEAIYYNVDIGHIYSTIDDFHFKSALVD
The following text describes a protein:
Function:
Binds bacterial lipopolysaccharide (LPS). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MLQIVFFSILFTFTFTESMKNDWTCNSQDAEITYSSCDAKKPIPIININPCLSWRKTRGNLSFYYVPRKDMKELYFNVHMELRSAIIVPKRKEVICRGVDDKYSFCRVLKGETINTTVPFSYSSLKFPKGLYIFIAEAFSGSTEDSMFCCNITLKLK
The following text describes a protein:
Function:
Protease involved in the processing of a variety of prenylated proteins containing the C-terminal CAAX motif, where C is a cysteine modified with an isoprenoid lipid, A is an aliphatic amino acid and X is any C-terminal amino acid. Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins, leaving the prenylated cysteine as the new C-terminus. The substrate specificity is only partially overlapping with that of FACE1. CAAX processing is likely required for subcellular targeting of prenylated proteins to the plasma membrane.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MATDGESISMSLAVATCVAMALFYVLILYVPTVILRLPSASSYTEFMIRRFICAAICTVASLVFTAFILPIKSWEASYILGVYGIRKDHLWQGVVYPLLLTSLVYAGSLVLKLFTLLESWKENGGGCSSFNYIRSFFQTIPASVLTSASNVSVWRNFIVAPVTEELVFRSCMIPLLLCAGFRINTAIFLCPVLFSLAHLNHFREMYIRHNRSYLRASLIVGLQLGYTVIFGAYASFLFIRTGHLAAPLFAHIFCNYMGLPVLYANGKGLVSAAFLGGVVGFVLLLFPLTKPLMYNDSTNDCPCWLGYCLWN
The following text describes a protein:
Function:
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Sequence:
MEDNFELEDCGDLSPILFACNLNSEIFTSNDLKTQLENQFLNFGLAHFVYLPSFRRMRVEYNTAEEAILAKISLHNTVFHDNEMHIYFSQSAMSTQDTTTSLAPPKAEKQFLISPPASPPIGWEPIEENKPMFNFDLISAVVELEPGQSHELHKATTTT
The following text describes a protein:
Function:
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
Sequence:
MTALRITSMDKQTLIAEAAAARLKAYAPYSNFKVGAALLTHDGKVFHGCNVENAAYGLCNCAERTALFSAFAHGYKPGDFNQLVVIGETDGPIAPCGACRQVILELGGTQLPVLLTNLKGDILETTAGEQLPNAFGGQDLKKK
The following text describes a protein:
Function:
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Sequence:
MGFNEFLSSIFGNKSTRDMKEIKPWVEKIKAAYPEIEALDNDALRAKTEELKKYIRESATDERAKVEELKASIESTELEDREEVFAQIDKIEKEILEKYEKALEEVLPVAFSIVKATAKRFTENEEIVVTATEFDRHLAATKDFVRIEGDKAIYQNHWNAGGNDTVWNMIHYDVQLFGGVVLHKGKIAEMATGEGKTLVATLPVFLNALTGNGVHVVTVNDYLAKRDSEWMGPLYMFHGLSVDCIDRHQPNSDARRQAYLADITFGTNNEFGFDYLRDNMAISPKDLVQRQHNYAIVDEVDSVLIDDARTPLIISGPVPKGDDQLFEQLRPLVERLVEAQKALATKYLSEAKRLIASNDKKEVEEGFLALYRSHKCLPKNKALIKFLSEQGIKAGMLKTEEIYMEQNNKRMHEVTEPLYFVIEEKLNSVDLTDKGIDLITGNSEDPTLFVLPDIAAQLSELENQNLTNEQLLEKKDELLTNYAIKSERVHTINQLLKAYTMFEKDDEYVVIDGQVKIVDEQTGRIMEGRRYSDGLHQAIEAKERVKVEAATQTFATITLQNYFRMYHKLSGMTGTAETEAGELWDIYKLDVVVIPTNRPIARKDMNDRVYKTKREKYKAVIEEIEKLVQAGRPVLVGTTSVEISEMLSKMLTMRKIEHSVLNAKLHQKEAEIVAKAGFSCAVTIATNMAGRGTDIKLSPEVKAAGGLAIIGTERHESRRVDRQLRGRAGRQGDPGSSVFFVSLEDDLMRLFSSDRIASVMDKLGFQEGEMIEHKMISNSIERAQKKVEENNFGIRKRLLEYDDVMNKQRTVVYTKRRHALMGERIGMDIVNMIWDRCANAIENNDYEGCQMELLQTLAMETPFTEEEFRNEKKDTLAEKTFNIAMENFKRKTERLAQIANPVIKQVYENQGHMYENILIPITDGKRMYNISCNLKAAYESESKEVVKAFEKSILLHVIDEAWKENLRELDELKHSVQNASYEQKDPLLIYKLESVTLFDAMVNKINNQTISILMRGQIPVQEAPADEQQPRRVEVRQAAPEQRQDMSKYREQKQDLSDPNQQAAASQDTREQQKREPIRAEKTVGRNDPCPCGSGKKYKNCHGQNA
The following text describes a protein:
Function:
N5-glutamine methyltransferase responsible for the methylation of the glutamine residue in the universally conserved GGQ motif of the mitochondrial translation release factors MTRF1, MTRF1L, MRPL58/ICT1 and MTRFR.
Subcellular Localization:
Mitochondrion.
Sequence:
MELWGRMLWALLSGPGRRGSTRGWAFSSWQPQPPLAGLSSAIELVSHWTGVFEKRGIPEARESSEYIVAHVLGAKTFQSLRPALWTQPLTSQQLQCIRELSSRRLQRMPVQYILGEWDFQGLSLRMVPPVFIPRPETEELVEWVLEEVAQRSHAVGSPGSPLILEVGCGSGAISLSLLSQLPQSRVIAVDKREAAISLTHENAQRLRLQDRIWIIHLDMTSERSWTHLPWGPMDLIVSNPPYVFHQDMEQLAPEIRSYEDPAALDGGEEGMDIITHILALAPRLLKDSGSIFLEVDPRHPELVSSWLQSRPDLYLNLVAVRRDFCGRPRFLHIRRSGP
The following text describes a protein:
Function:
Serine/threonine-protein kinase which plays a redundant role with pak-1 in embryogenesis but, in contrast to pak-1, is not involved in commissural axon guidance of ventral cord motoneurons or in distal tip cell (DTC) migration.
Sequence:
MNRTFSLRRKVKKSEISTPSNFEHRIHAGFDARSGTYTGLPKQWQALLGPPRSISRPKPMVDPSCITPVDVAELKTVIRGPSSSFRYNSPLPFGMTNSPMPSVARSNSLRISATASPVVNVSSARHSFRPTLPPVSQRGYPFNDPSYAPLPLRNQKPPMSTTFGVEKPHQYQQIITIVAPSRTTTPQLQPKSPSTPQAMRQQPKCTEGVSDEEFRNALKFVVDGTDPRSDLTDYKQIGEGSTGVVEAAYKISTKQIVAVKRMNLRKQQRRELLFNEVSILRQYQHPNIVRFFSSHLVDDELWVVMEFMEGGSLTDIVTATRMTEPQIATISRQVLGALDFLHARKVIHRDIKSDSILLKRDGTVKLTDFGFCGQLSEEVPRRRSLVGTPYWTAAEVIAREPYDTRADIWSFGIMLIEMVEGEPPFFNDQPFQAMKRIRDEHEARFSRHAKVSVELSELLSHCIVKDVNKRWPAKDLLRHPFFAKAQHSSSIAPLLLQLQGNTINGNNPPTHHHSSQITTVIQ
The following text describes a protein:
Function:
Functions together with the other V-type ATPase assembly factors in the endoplasmic reticulum to efficiently assemble the V-type ATPase membrane sector V(0).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSYWVELWESIFTPGVTPVLAKSAHVACGALVAVFLGLYIGTKSIHCLILFFLAICLWLSLTWFLVELAHARVNNDLQMSSQSANKNDDNSNNQNPSNNKEMSDKESDSATTTQTFSVPEELLRARTTANNS
The following text describes a protein:
Function:
Catalyzes the decarboxylation of 3-oxo-tetronate 4-phosphate to dihydroxyacetone phosphate (DHAP) and CO(2).
Sequence:
MQWEKERKEIVRVAKKIYKKGLVTANSGNFSVRTANETILITPRSKSYERLKFSDIIELNFDGKVIEGSREPSSEYRLHIEIYKRRKDINAVIHTHSTFACALASLNQSLPVILDEQRTVFGGEVRVAKYAVSGSEELAKEAVKALKNRKAVFLSKHGAVAVGKNISEADTICELLEKFCQIYVFMRLLQK
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MIQTGAVGSLKGHFQVSPSHEEPMGMWEEASDTGMKGKEDKNERNKRIVNLTLEMIYLLTGEHYIPRKKSDDGGALHAPGSVIQKENNKNDKKILELMSNIIQLLTGEERDYIKGNKDLYDEEIKEEPQQLSPLAVCEYKDESNVTANMEATLGCNNDGNLTEISPVEQSPPANGIKVEVDSWEEENQSDCSINPLTEQIQGTDTPTPIMGCSPSNNLSDNYISVVIKEEATSWEEENPFAEQTQVTDTSTLVGQSLNSSLIPKDTSDGIKEDLALWETDHNYCKINTITGEILQTDKLADVMGCSLNNNSQDDYISFVIKEEEASCEEGNQSDCSINPLTEPIQGTDTPTPNMLYSLVRDFLKTNGNKYDENANTSAHFSRNRDSDKHERTHTGKKLHSCSQCGKCFSSSSDLMAHRRQSHTREKPFSCSECGKCFSFRSRLIDHQRTHTGEKPFCCFQCGKCFSVRSRFLDHRRTHTGEKPFSCLECGKCFLFRSRLLEHQRTHTGEKPFSCLKCGKCFSVRSRLKDHQRTHTGEKPFSCLECGKSFSFRPCLIDHQRTHTGEKPFSCFQCGKCFSFQSRLINHQRTHTGEKPFSCSECGKSFSNQSCLRVHQRTHTGEKPYSCSECGKSFVTSSQLAVHRRRTHTGEKPFSCSECGKCFSNQSCLRVHQRTHTGENLFSCSECGKSFVTSSKLASHQRQTHTGEKPVSCSECGKCFTRKRSLKVHFKIHTGGKP
The following text describes a protein:
Function:
Involved in sister chromatid cohesion. Forms a complex with SCC2, which is required for the association of the cohesin complex with chromosomes. Binds to the nucleosome-free promoter regions of ribosomal protein genes and tRNA genes.
Miscellaneous:
MISCELLANEOUS: Present with 907 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Note=Associates with chromatin.
Sequence:
MENLGDKLSISQVYHLAQEYRDHAYSIANKIGSEEGLKQYYGLMNMSIQMFQLLKTKCTLSVLEDSKVTFEMVELLIQETYNFDLAELYISSLKERLQTHQSDTDLVEEIMRCEFLLLHDLPLMRDSKFHYKIALRNCNELVQYMVNLQDELYQNWASVFQYVGVMLCIKLKQHRRVKTSFHGLLSQCREKSQWKWFLNLCYVNYLLNERFPIPEDALQELRSTELHTVGPELYAWKLALEMVIQLCKDGNITDHLNEFKNFFDTNKQSLVTNEGKGCVIKIMPRIALKVELPMIFHYKELKNILLLLQSVSYIVNCYDEKGNFSRKFLPKVYSTTQKLIKNIAAGGVSMNELDSRIQTYKSILEFCEFYKVWEQTLLKGAVVTTESPKLGPSPGYVRLLQAMKVQFEGGGAVEEYTRLAQSGGTSSEVKMISLLNCYTVQAARVSRCSGDKQGELVEQCNKVWLQVEKLLQETDLQFNPIWECTVTILWLFSHFEPFSWNPLPCSDKQRAEYVSKLREFYSSNKFVAGEAVADNRFKLKKALLLQILVNYLGGRMLEHDLGEIYAISAKCFDMCRQQGGMRKVQYVIGIWHLMNCTVAMRGKDVALTNAKLEALVKQITSVKQ
The following text describes a protein:
Function:
Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.
Sequence:
MALNPHQRKKVDINAMTEEEQKLFRLYGKLPPKKNVAKHNLMERKYFDSGDYALSKAGKTAPQSVGTTIPSPENIHHASHTSTPTPTGQHPSMTHLNSESNSANPGVLPKHGTDGPILEAIDNAIVTDGNAHPSTEQAIEPSQPVNLQ
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
Miscellaneous:
MISCELLANEOUS: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MDLIYFIKAFFLGVIEGITEFLPISSTGHLILIGDWINFSSNEEKVFEVVIQLGGILAVCWLFRDKIINLINGVLKSDPVAQRFAVIVMISFLPSAIIGALFIHDIKNVLFNTTVVATALIVGGLIILWVENRKDSEKFKIENIEKIGFKQAIIIGIAQCIAMIPGTSRSGATIVGGMLSGVSRKAATEYSFFLAIPTMLGAAIYDASKNYHLLNTDDILAILIGFSAAFISALIVVNALIRFVAKHSLSVFAWYRIALGLIIFSVN
The following text describes a protein:
Function:
May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle pole. Nucleus.
Sequence:
MGGSGRAGARGLRRRRGAGNMASRPKRRAVSRVPPALGDEEEEDEVEEQDEDDSDEEEDEEDEVVNEEVNIEFEAYSISDNDYDGIKKLLQQLFLKAPVNTAELTNLLIQQNHIGSVIKQTDVSEDSDDEVDEDEIFGFISLLNLTERKGTPCAEQIKELILRLCEKNCEKSMVEQLDRLFNDTARPVGFLLSERFINVPPQIALPMHQQLQKELAEAHRANKPCGKCYFYLLISKTFVEAGKSNSKKKRSNQKKDELMFANAEEEFFYEKAILKFNYSVQEESDTCLGGRWSFDDVPMKPLRTVMLIPGDKMSEIMEKLKEHLSV
The following text describes a protein:
Function:
Represses ulaG and the ulaABCDEF operon. Two ulaR binding sites have been identified in each promoter. Full activity requires simultaneous interaction of UlaR with both divergent promoters and seems to be dependent on repressor-mediated DNA loop formation, which is helped by the action of integration host factor.
Subcellular Localization:
Cytoplasm.
Sequence:
MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNANPEILQQLEAQGVSILRV