lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Putative Notch ligand involved in the mediation of Notch signaling.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MRTFFNDRTSERFQVPEDIKKGPRKRAGGQAGGESQDLELKTRDTDHVIERLAYSGLVLPSAEWHTLRHPGVRAQLAYRVRVTCAANYYGPSCWSLCKPRDDRFGHYRCSPEGRKVCRPGWTGSTCESPVCRRGCHPVHGYCDRPGQCLCRPGWKSELCDHCQPYPGCRHGYCNNTPWQCICDVNWGGILCDQDLNYCGTHEPCFNGATCEHTIGQDKYLCRCRQGFFGRNCELGQGQAQRPCLASPCLNGGTCSERNSTFECACLPGWTGNRCQKNVNECSSSPCLHGGTCLDLVAGYRCLCQPGWRGSSCETPDDTQASPAKHSGAPDRETPSPCAACPKGSRCVLGPRSQVQHYINDCATRPCVNGGTAWTAEQLPLPLPDGWEDLLHNNRNECHPNPCHNDGKCTDLIADFLCECQGQWKGKTCNLNINDCATRPCVNGGTCVDGLNSYRCLCPDGWEGPHCSNRDSHCDSSTCLNGGTCEDLGDAFVCHCPENYQGHTCQIAKGSSCESNPCQNGATCVNRGHSFSCICREGFEGRLCQQNVDDCRGQPCHNGGRCIDGVNWFRCECASGFAGPDCRINVDECASSPCAVGSTCQDAIGDYFCSCPPGRTGKRCNVGTVYPEGSRWQLDCTLCSCTSGSVTCSPGPCPESGCDPVGSTGQCPLGQTCLARAPEACFVNPCPTGGPRGDCSDVANASHAAKPSQCLPNSADPSNNCAKMTLLFDRRTMTPGTTVESLCNGVRQLSPRPSILILCAQRMADPDSIEVTLSMPGHASASTYAAVSESARRLADLISRKLTNSTALASVIEVKNEENVRRYCNPIREPTELCELDPRNKAHLFKALPLDTSKNTNHLAEVTNKQCQKDALLTTRPSTAGPKALLESSDDKLDAVVVLV
The following text describes a protein:
Function:
Polarity factor involved in localization of polarized growth and cytokinesis. Forms an intracellular gradient that serves to measure cell length and control mitotic entry. Controls the timing of mitotic commitment by regulating the inhibitory impact of cdr1/cdr2 on wee1 activity. Directly phosphorylates the tail of cdr2 which inhibits cdr2 activation by ssp1. Cdr2 phosphorylation by pom1 also modulates cdr2 association with membranes and inhibits cdr2 interaction with mid1, reducing its clustering ability, possibly via the down-regulation of cdr2 kinase activity. Acts as a negative regulator of mid1 distribution, excluding mid1 from non-growing ends, which prevents division-septum assembly at the cell ends. The pom1 polar gradient also mediates mitotic entry by regulating cdk1. Plays an essential role in proper localization and phosphorylation of a GAP for cdc42, rga4, which ensures bipolar localization of GTP-bound, active cdc42 involved in F-actin formation. Phosphorylates multiple other substrates that function in polarized cell growth, including tea4, mod5, pal1, the Rho GAP rga7, and the Arf GEF syt22.
Subcellular Localization:
Cell tip. Cell membrane; Peripheral membrane protein. Note=Forms an intracellular gradient that serves to measure cell length and control mitotic entry. Localized to the cell division site at the time of cytokinesis. Tea4 recruits pom1 to the cell cortex from where it then moves laterally at the plasma membrane, which it binds through a basic region exhibiting direct lipid interaction. Pom1 autophosphorylates in this region to lower lipid affinity and promote membrane release. Tea4 triggers pom1 plasma membrane association by promoting its dephosphorylation through the protein phosphatase dis2.
Sequence:
MGYLQSQKAVSLGDENTDALFKLHTSNRKSANMFGIKSELLNPSELSAVGSYSNDICPNRQSSSSTAADTSPSTNASNTNISFPEQEHKDELFMNVEPKGVGSSMDNHAITIHHSTGNGLLRSSFDHDYRQKNSPRNSIHRLSNISIGNNPIDFESSQQNNPSSLNTSSHHRTSSISNSKSFGTSLSYYNRSSKPSDWNQQNNGGHLSGVISITQDVSSVPLQSSVFSSGNHAYHASMAPKRSGSWRHTNFHSTSHPRAASIGNKSGIPPVPTIPPNIGHSTDHQHPKANISGSLTKSSSESKNLSTIQSPLKTSNSFFKELSPHSQITLSNVKNNHSHVGSQTKSHSFATPSVFDNNKPVSSDNHNNTTTSSQVHPDSRNPDPKAAPKAVSQKTNVDGHRNHEAKHGNTVQNESKSQKSSNKEGRSSRGGFFSRLSFSRSSSRMKKGSKAKHEDAPDVPAIPHAYIADSSTKSSYRNGKKTPTRTKSRMQQFINWFKPSKERSSNGNSDSASPPPVPRLSITRSQVSREPEKPEEIPSVPPLPSNFKDKGHVPQQRSVSYTPKRSSDTSESLQPSLSFASSNVLSEPFDRKVADLAMKAINSKRINKLLDDAKVMQSLLDRACIITPVRNTEVQLINTAPLTEYEQDEINNYDNIYFTGLRNVDKRRSADENTSSNFGFDDERGDYKVVLGDHIAYRYEVVDFLGKGSFGQVLRCIDYETGKLVALKIIRNKKRFHMQALVETKILQKIREWDPLDEYCMVQYTDHFYFRDHLCVATELLGKNLYELIKSNGFKGLPIVVIKSITRQLIQCLTLLNEKHVIHCDLKPENILLCHPFKSQVKVIDFGSSCFEGECVYTYIQSRFYRSPEVILGMGYGTPIDVWSLGCIIAEMYTGFPLFPGENEQEQLACIMEIFGPPDHSLIDKCSRKKVFFDSSGKPRPFVSSKGVSRRPFSKSLHQVLQCKDVSFLSFISDCLKWDPDERMTPQQAAQHDFLTGKQDVRRPNTAPARQKFARPPNIETAPIPRPLPNLPMEYNDHTLPSPKEPSNQASNLVRSSDKFPNLLTNLDYSIISDNGFLRKPVEKSRP
The following text describes a protein:
Function:
Required to activate transcription of PDR3, a gene involved in retrograde regulation of multidrug resistance, a phenomenon that takes place in cells that have lost their mitochondrial genome. Also required for ubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. Its precise role in H2BK123ub1 formation however is unclear and is independent of retrograde regulation of multidrug resistance function.
Miscellaneous:
MISCELLANEOUS: Present with 2060 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSGYTGNNYSRYSSTPPRQRGGYHHARRSRGGAGGSYYRGGNASYGARYNSDYEQPPQEGDLRQTGAYYRNGYTDTRPYYSANSRHYQAQPSPRYNNGTNSYHLPQRGNSQDTNGRTTSASQEDNDEKRVKSRYRNMQADHPRQQPMSVGSTSSRNGSSGNSSTSSTSNGLPPPPSVSSITNNRSYHSSAYPYSSSHTYNNYHHRETPPPPPSNGYYAKGYPVHVPENRSNSDGSSSSVVKKKRILDMKDSPFIYLTDFDKNVKKTNNTESECEKAREVFKESDSIDSALEELNLKINSNELELRLLNNQCDKHALNIQLTQEKLDSLLLMQ
The following text describes a protein:
Function:
Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Subcellular Localization:
Mitochondrion.
Sequence:
MCLWIHTASADQTPQSRLLEASLAHVSEHGWTLQAIRQGARSLGYTDVTHGLLTRGPIELVEYFIQSRTKMIGPALAKEQVDLSQMGVTARVRTACIARLMMTGPYIHKWPQAIALLSQPQNLANTARDLGGLVDEIWFLAGDRSLNWYTKRLILSGVYTSSELFMTTDKSKGFEQTYKFLDRRLKDVGGFGKAVSDVSNVVNFGVRSAMGILQSVSSAVDLPTV
The following text describes a protein:
Function:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Sequence:
MPGLVTATGVLAFLADEEPELKVFALKTLNDDIDTVWTEVAGALTQIEALYEDETFPERQLAALVLAKVYFHLQAYNESMTFALAAGPLFKLDAPSEFEETIISKCIDQYIAVSSLHHTPSKKDLPALETDLGSGAIDSSALISPTTPFSQSSVPSKSLLARASSDDNTILDPTFQPTKETRSASIAQVHDTATQVALQNVIERLFESCLKEGKYRQVVGIAVEAKNLDVLRRVIKRANQDVKSGKAKVQEGSQGPAEELMDYALSICMDIVQERGFRTEILRLILDLLNDIPNPDYFAIAKCVVYLDSDEEASRMLRQLVAKGEQDSIAIAYQIAFDLYDNSTQEFLGKVIKALPSGEPAKPKPAEGSNDAAAEREPLLEGQESSEEELPEEVAKVYKNIRTILDGSKVIKLNLEFLYRNNHADMSILNKVRDSLDGRNSIFHSAVTFCNAFMNAGTTNDRFFRDNLEWLGRAVNWSKFTATAALGVLHRGNVTQSRKLLEPYLPRPSGVSTGSVYSQAGALYAYGLIHANHGADALDYLHQQFKDADQEVIQHGGALGLGIAGMGTGDQKIIEDLKEALYSDSALNGEAVGAAMGLIMLGTGHAATIDAMFTYAHETQHEKIVRGIALGIALIMFGQQEGADRTIQLLLANPDPILRYGGVLTLAMAYCGTGSNKAIRKLLHLAVSDVNDDVRRVAVMSLGFILFRKPGSVPRMVELLAESYNPHVRYGSAMALGIACAGTGLDEAIDLLEPMMKDPTDFVRQGALIALSMILVQQNEVMNPKVAAIRKTLKKVVSDRHEEQMTKFGAALALGIIDAGGRNCTIGLQTQTGNLNMAGIVGMAVFTQYWYWFPFTHFLSLSFVPTSIIGLDSDLAIPNVKFHCATRPSLFDYPPEQEVKVEEGPALVTTAVLSTTAQAKRRAQKKEKAQRRESMDIDTPAVSKTASQPAAEDKMDIDDDKKAAAKPEESKEKKEGESGEKEATGATDAKKKAEKEKVGYEIENMSRILPGQLKYISFPAGRYKPVKKPTGGPLLLFDTQPSEAKSLVEEKLNKVTTERAPVAGAGASGASDGTPRLSGGAAQSLLSQLQGTGAFNRSSMRELSELLQLGQRMEQDASAGLGESRARGAGGAAAGSGTGASATAGSGAGAAAAAAVLNAVDEDAEGDEEAPTPAEFEYFTDAEADDEE
The following text describes a protein:
Function:
Transcription factor that regulates alternative transcription start site usage when cells switch from growth in exponential phase to stationary phase, and acts on genes involved in translation, glycolysis, glycogen synthesis and mitochondrial proteins.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MDPSLLHSSEEVKPTSNTSSGGSNYPSPNTAGQSHTTDNTSPSTVPQSQSTSQTHNQPPQPSSQSQSQPGQDTSALDDNESAKRPRLRLAHACDRCRRRKIRCDTQHPCTPCQQSNNVCTFETPSRRTVKSKGNSERVSSTGGVKRPHSPGRVFASLATGRGESQSNLEARLAALESMLRDVPPNVHNAFLSTLDARLGSGTGVGLKEGGGGGEGVGVAVEALAGTSLANLNLPGNLGYNMGGSELNAQRRLGQNTLSPDWAATGGLSGWLNDAVLGKKKEEAGMDELAKRLGGMSFFYEDEIGQAKWQGATSGFPLLHLLAAHNAPKEEDEADSADGDVSGEMMASPAADSIPSTSPNTSVILPRRISSSSTPAGRASSVHAKARSSSIGLGAIGRRASSADRRKKERFFPDRTPRPHQTLNPEASWKVITGVIPPDLMDTLVRCYLSTSHLLWPFLHVPSFLTDYANPAQWGEPGFTCFIVAVCTLSSRHVDDPRVRANPADPSTAGKQYFELFKRLRDLPSADRPTLYSIQAAFLAAIYAFGLGNLSKAFSLQAESITLCLDGGLHRSVDAYDHFDAIEKETRKRTFWSIYAWDKQSAALFGRPPIIHLRDCDVTEPLIVDDENLSPEGIKDESINSKSRMCAFVATIRLHVILEGVIDSATQPSAFPTSPFLARAAATIARRTAQNETLRDEEELLEEWKRILPKYWCYDTETANSRDPIRITQAERLHCLEHLVKMIIYRHRFSGFVAMPASTAEERARHLDLCRKAMQCALTIIADHVHISQRGMMTYYGVHVIHQLAQAGRTLVAVILNCRNADFRPIIAPSVEGLRSCVGLLRRFSGRYLCGLRSADIIDEFCRVCNIPVDSPRVPNSAGRPSPAWLRPVRKRVATPPPIADSPGSSGMMNFDPNTLTANSGAHASGVNDNMGISAGGVGNIGGPASDLDALFNTAAYFNVPGGEVSGGMAGTSTGSAPNVGNHNVNIGPSNSFLPTLGGLGEASAPYDRFETLSPNAELGNGNTMLSNYQDSHAGFSLSGDTDHPMGNGLGTSAGAGAGHISFDYGLNGHGFGGESLATKGMDNVSDGLKQGTGGSNLSAATILSLMEEGSFDYGSIFTDQAP
The following text describes a protein:
Function:
Affects mRNA transport from the nucleus to the cytoplasm.
Subcellular Localization:
Nucleus.
Sequence:
MNTNSNTMVMNDANQAQITATFTKKILAHLDDPDSNKLAQFVQLFNPNNCRIIFNATPFAQATVFLQMWQNQVVQTQHALTGVDYHAIPGSGTLICNVNCKVRFDESGRDKMGQDATVPIQPNNTGNRNRPNDMNKPRPLWGPYFGISLQLIIDDRIFRNDFNGVISGFNYNMVYKPEDSLLKI
The following text describes a protein:
Function:
Inhibits elastase.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MKIIMCIFGLAALAMAGETDLQKILRESNDQFTAQMFSEVVKANPGQNVVLSAFSVLPPLGQLALASVGESHDELLRALALPNDNVTKDVFADLNRGVRAVKGVDLKMASKIYVAKGLELNDDFAAVSRDVFGSEVQNVDFVKSVEAAGAINKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKGSWKDKFVKERTMDRDFHVSKDKTIKVPTMIGKKDVRYADVPELDAKMIEMSYEGDQASMIIILPNQVDGITALEQKLKDPKALSRAEERLYNTEVEIYLPKFKIETTTDLKEVLSNMNIKKLFTPGAARLENLLKTKESLYVDAAIQKAFIEVNEEGAEAAAANAFGIVPASLILYPEVHIDRPFYFELKIDGIPMFNGKVIEP
The following text describes a protein:
Function:
Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglycosylase (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MLSFTSVFSFFLHALLLKTAFSYVIKRNNPVFDYTSEKVRGVNIGGWLVLENWITPQLFTQFSSMSNPPTDEWGFCEVLGADEAASQLAAHYSSFYTESDFATIASWGVNVLRIPIGYWAFNVVDGEPYVQGQEYWLDQALTWAEQYGLKVWIDLHGVPGSQNGFENSGKTGSIGWQQNDTVTRTLDIITYVANKYTQSQYASVVIGIETVNEPLGYGLDMDQLKQYDLDAYNIVNPLSSSVATIIHDAYVDLSIWDYGVVSPSSYNLVMDVHRYQLYESDECSKTLDDHLSDVCSIGDSIASSPYITVTGEWSGTLADCTIFEEGVDSSTFIGPNSGDISTWTDEYKGAVRLFIETQLDQFERGAGWIYWTAKTGGPSPTWDMGLLIEYGVFPQPFTDRQYSSYCG
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MGIGAKKNAQKQKKINPFELKFNKSKYDILGRKKGAQVGAPTASRKRAHEQREKTLGVEFDRKNKISKIVDKRLGERDDKTEEEKGAMRFTEERVKNYKRASKFNLADDQDEEEVTITHKGKSLSDIEKYDKSMISDSDDDEEPGNLGSQMVRIAHFGGGEKTAEEMVKEKISREDMISNLIAKTKLARHEKQQQKDELVSELMTESLDSKYAALMAKMKSSFRPTGRQQLEKDDYDRLAITLKTEADARATPADRKLSEEEEALKEKERLDSLEAARISKSNASLNSRSHVSADADVDVDAGAKADSRKLKAKNARFEVKFDDEGGLIDGDVERSRILKTSGDSDEEEEDDELDDEEEEEDLDDLMEDEEELEDSEEDEEEEEAGVKKGKKSKETVATDLPFVFEMPKNYKKFCALLEKHAESMDLVLERLVKCHHPSLKEGNKKRLNKMFLMVLRWFDDMAKEEVTMQSVKEMNLAQATMFSLMKFDIQYGVRCVRALIRQHWKGRQEKEAKSPASFGLISAIRLVSGLFPVADQWHPVVVPAFFLATEALCSAKIPNLGVLARQIQLANAIVEYVAESKRYVPELVAFARSALLLAVTEKPEKFSTNGFPISAPHSEMLCVREKITDAALQPISLGSIFNETLPDSPSLKITVLRALLSLIQHLRVMYTAQNETYNIVFEPFLKTLNAIQTENLPKEVQEELETLIASMKAEIGAKRRLVHLSLVKTEKSMLKMLEPRFEWDFDPERPHKGPKDDKKKLVKNLRNEQRGAIKELRKDTAFLARKQMSNVKSKDRARIAATKRVMGGLMQQQGEWNKEKRTADVEKKKTKK
The following text describes a protein:
Function:
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Sequence:
MSEFEALGVHQWLSKQCAYMALHHPTPIQKLCIPSILAGKCVVGGAATGSGKTAAFVLPLLQILAEDPYGVFALVLTPSRELAYQILDQFVALGAPLHIRAALAIGGVPHEQQVSVLHGRPHVVVATPGRLKFLLGTFPEARKAFSHLRFLVLDEADRLTTDDMEGDVSDVVELLQPPRPTRRTLLFTATLEQHLVRVEKGGWLERLGISDAAGQLEVHATNTVMNMPDVARKSDNESSGSGNSVGTSYTVADSLRQTYLFIPNMVKLAYLVAALRSVGSDQTTIIFANSCMRCEIVRLTLQLLGFPVCSLNSIISQKHRIDNLATFKLGIARVLVATDIASRGLDIPAVGAVVHYDLPKQSSTYLHRVGRTARAGRKGLSVALITENDVSLVKRLEKKLQCTLELWKVKGVGEKDVLKILDEVSSAKVQAKLQIEDQFGERVETLKAHAAAKKVIRQVKQKKTKNGAFAATPNKRDKMQVGKHLPNLLAGEAGTQTKGVRKPTKRDRNDSPEETSMAGE
The following text describes a protein:
Function:
ATPase component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Acts as a molecular motor to provide the energy that is required for the export of proteins (Probable). Required for type III secretion apparatus (T3SA) formation, proper protein secretion, host cell invasion and virulence. May play a critical role in T3SS substrate recognition, disassembly of the effector/chaperone complex and unfolding of the effector in an ATP-dependent manner prior to secretion (By similarity).
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal domain is required for oligomerization and ATPase activity. The six N-terminal residues are necessary for proper oligomer formation, though their absence does not entirely preclude oligomerization. The extreme N-terminus is also required for interaction with MxiN/SctL. The N-terminal domain, not ATPase activity, is responsible for localization of Spa47/SctN to the injectisome. The binding of ATP induces a conformational change of a highly conserved luminal loop, facilitating ATP hydrolysis.
Sequence:
MSYTKLLTQLSFPNRISGPILETSLSDVSIGEICNIQAGIESNEIVARAQVVGFHDEKTILSLIGNSRGLSRQTLIKPTAQFLHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDFGEYKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR
The following text describes a protein:
Function:
Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
Sequence:
MSDDGGGRKNLRMPEDDEVFAEVTDMLGANRVQVRCADGEERTARIPGRMQKRIWIREDDIVLVEPWDWQDDKADVTWRYEKSDADQLREEGHIE
The following text describes a protein:
Function:
Has dehydrogenase activity against corticosterone (11 beta-hydroxysteroid) and estradiol (17 beta-hydroxysteroid), with similar activities to both sterols in the presence of NADP(+), but negligible activity to either sterol in the presence of NAD(+). May be involved in signal transduction regulated by various sterols.
Subcellular Localization:
Lipid droplet. Membrane; Single-pass type II membrane protein. Note=Surface of oil bodies. Exists at a monolayer lipid/water interface.
Domain:
The proline-knob motif may be involved in the targeting to oil bodies.
Sequence:
MDLINSLLNFVVPPASLLMLAFTWPTLFFITTCEWLYNTYLNSENMENKVVLITGASSGIGEQIAYQYAKRGANLVLVARREHRLRGISENARRLGAPNVLIMAADVVKEEECRRFINETINYYGRVDHLVNTVSLGHTFYFEEASDSSVFPILMDINFWGNVYPTYVALPYLRESNGRIIVNASVENWLPLPRMSLYSAAKSALINFYETLRFEVKNEVGITVATHGWIGTEMTRGKFMVEEGAEMQWKEEREVHVTGGPVEEFAKQIVSGACRGDPYVKYPSWYDIFFLYRVFAPKVLDWTFRFLLTNGGARRTSFIGTGRPLLETSSPRRSAVMEGSSPRRLPPGPLTFSPAFQQQKSE
The following text describes a protein:
Function:
Transcription factor involved in the regulation of multidrug resistance genes. Acts in concert with YRR1.
Miscellaneous:
MISCELLANEOUS: Present with 125 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSKRGSLQDRASPSEETVKKAQKRRKPIKSCAFCRKRKLRCDQQKPMCSTCKTRGRSGCLYTEKFTHKIETKELFGSTPNIELLKRIEDLEKRLDDKELTEKDVALSTSPFRNPYANFYYLQCKGSGRRIVYGPTSLRTHLSNDDNRFVNTYNQLWSKVKIERNRWKARHKWTMKPETQLLEGPPLEKTGSDILQQVCNVLPSFEQSSKIITDFFNTELETNEVSEVLDKTKIINDFTSSFLPSDELLPNGERRIEKLLPSTKKNYYKIGVILMILCIRHFYKNTPEEIEKFLIMLTGLSTAKVYFIERAQFLLLKYYHRELIWACGDDSHMISLVDLLCSTAIMLGLHLNIREIYKNQENIVGSMESLENLWVWIILSDFNVSLNIGRCLAINSSYFQVDECENGERLPKNTNNYSSTVFFDQSNSCMGKLKRFLRLARPMLDQIYDRSAFPDLAENCKKLRNFVETEFHPISYYTDSELISKVPLCEIKVLAQVLNLLLTFYSLRYLIYKEKSVVLENNILQTILVSFSLVINTTILCFNLDEKHFPEFFDHNCVHLPPFMALSLVYTNFLFPRASTGFCAFLYHKLTLFEKGYYLSSNIKDQEVTDWDLSTLNIPLDKAMNLLTAFKIHSDIFAKWSNDNNKQLRIIMARSYTFVINIALESIYRAVLEKVIKYRTEVENTWLQQLQDELNGSYSLTDNVNTPIDPSLSDLGVTSASPLAGNSPGLPPEEVRNNSENASHNNETGPIETELAQTISNEFWTAYNLGWEELMSQPDYKYLFDTQ
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MQSVPTDPHEFDELPISNVLKKALKDNKFTKMKQIQSMAIPHLLAGRNVLGASPTGSGKTLAFLIPAIELLTYARARPANGTLVVILSPSRELALQTFSIANTLMKQLSPTVGCVVGGSTSYKNEAYQLTKKGYNMLIATPGRLRQHLEAGNVKLDNFQMLIIDEADRMLENGFAQDLFQIFKSIKTPAQTALFSATLTKDVEGLMRVNISSAPVFCCPTEANVVTTLEHCYTIVPLKMRIATLVTLLMKLKGKRIVVFVNSRKEAEFLGRIFNAIDIDNDCIHGDLPQEERSLAFVRFNRNERSVLIATNVVSRGIDFTGVDWSISLGPPDRVKDYIHRAGRTARNENFGRSLILLCENEKPFVDSVRRAKITIKRINLKLEGVEDEFEHIKQTIPESRAFKELAEDAVDAFESSYSARPAEEGISVKDIDINDLRESFGLQPLK
The following text describes a protein:
Function:
Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSLKAKIDVFPFDGYLLQDPSVVSVMQAVVRGNKTGGTGVGNSGGASGNETGSGGVGGGNANKRREAGGGTTNSERRIKTPLEKLMSLRARCREQQRVQSVEGVLLVHAHDHPHVLLLRHNVKTTNRSRVLPATNTNSTAVYRLPGGRCRNGEPEELCLLRKLGRDLLNESKRLTSSSTAEEERSEVVVDVGSAHPNGTAVTASSSSFRVGEVLARWYRPHFDPLMYPYVPAHVAENDVREVRTIFLVHMPPRMLLTGTYGDEELVAAPLFDLYDNTAKYGVLIASIPTLLSRVNINYCR
The following text describes a protein:
Function:
Possible ligand of InR/insulin-like receptor.
Subcellular Localization:
Secreted.
Sequence:
MTRMIIQNSGSWTLCGAVLLFVLPLIPTPEALQHTEEGLEMLFRERSQSDWENVWHQETHSRCRDKLVRQLYWACEKDIYRLTRRNKKRTGNDEAWIKKTTTEPDGSTWLHVNYANMFLRSRRSDGNTPSISNECCTKAGCTWEEYAEYCPSNKRRNHY
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MYLSKIICKKVPMKLLCTRNAATVSAAATNALQKEQPSGEAMIARPRLVDLDKRWGIMSQEEKDGLITDLYARQKQPWTTLSIEEKKAAYWIAFGEHGPRAFSHISQKTVFWGTVAGLTIGVVLFGLIRTQAAPSPRTMTREWQEKSNEYMKENKINPISGEASEGFKGRGQISGGIFSPSEKDKK
The following text describes a protein:
Function:
Cell wall formation.
Sequence:
MADKPQTRSQYRNKQSGGSKKKSQKRGKRVAANIFKTIFFVGLFLAFFGIAAGATVFYDYAKDAPKLTDSKLRDPLSSKLLDKDGKVFAEVGTERREYIEYKDIPETLKNAILTTEDARFYEHDGIDPIRLGGAVIANLTDGFGAEGASTLSQQIIKMSYLDYTNKTLARKAQEAWLALQLEEKYSKNDILEIYVNKVYMSDRVHGMQTASEHYFGKNVKDLTLAQTALLAGMPQSPNNYNPYEHPEAAKKRRDQVLTNMYTHDKITKEEMTEAQKTPITTGLRSKKDREDKIYKYDSYVTQVLSEIPKEYDVYRDGLTIHTALDRDAQEYTEKMLNTNEIVNFTDDEMQAGIVLQDTKTGRVQAIGGGRKQKVTRGYNYATQVKRSVGSTMKPIADYGPAFEYLDWSTAHILEDEPYTYSGGTPINNWDFGYKGPISVRQALYQSRNIPALKTLQAVGLDKSEEFVNKLGITYDEGQNVESNAIGANSSNPMQMAGAYAAFGNKGIYNKPHTVTKIVLSDGQTEIDTEPQSTVAMKESTAYMVSDVLKDVLSIGTGTSAAVPGVPAAGKTGTTNIPPEFTSKYYYPSGAARDSWFAGYTTNYSIAVWTGYDDKKKYVSASEQKIAQRMFSKLMAHASAGKTTADFKMPSNVVSVPILKGSNPIARAAQGTSSDKVSYELFLSGTAPTKTASTPEDEKKKAEEAAKKKKAEEDKKKTDEEKKKEEEAKKKAEEEAKKKAEEEAKNLTAPAGLRASYNAGSKQINVSWSAVEGATYEVTVNGSTTTVSSTSVSVSGGNPGDTVSINVVAVKDGKRSPASSTTVKIPDS
The following text describes a protein:
Function:
Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of nanometer-scale pores (pinholes) causing host cell membrane depolarization and endolysin refolding and release into the periplasmic space. Once the pinholin has permeabilized the host cell membrane, the SAR-endolysin is released into the periplasm and breaks down the peptidoglycan layer. Determines the precise timing of host cell lysis. Participates with the SAR-endolysin and the U-spanin protein in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell.
Subcellular Localization:
Host cell inner membrane; Single-pass type II membrane protein.
Sequence:
MMLDTATEAGKGTLAVTGVGIAVYSPYEIASLCAAVLTALYVGAQLITLLPKMLDSIAELRRRFKK
The following text describes a protein:
Function:
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and abscisic acid-inducible transcription.
Subcellular Localization:
Nucleus.
Sequence:
MPSEIVDRKRKSRGTRDVAEILRQWREYNEQIEAESCIDGGGPKSIRKPPPKGSRKGCMKGKGGPENGICDYRGVRQRRWGKWVAEIREPDGGARLWLGTFSSSYEAALAYDEAAKAIYGQSARLNLPEITNRSSSTAATATVSGSVTAFSDESEVCAREDTNASSGFGQVKLEDCSDEYVLLDSSQCIKEELKGKEEVREEHNLAVGFGIGQDSKRETLDAWLMGNGNEQEPLEFGVDETFDINELLGILNDNNVSGQETMQYQVDRHPNFSYQTQFPNSNLLGSLNPMEIAQPGVDYGCPYVQPSDMENYGIDLDHRRFNDLDIQDLDFGGDKDVHGST
The following text describes a protein:
Function:
Involved in autophagic vesicle formation.
Subcellular Localization:
Preautophagosomal structure membrane; Peripheral membrane protein.
Sequence:
MTQDYEICRGVWESKIPVEIVLESDEVLEQPKPFYAMLPRVSYFPLILPKVINYFTSTCEELRLEQDKLWLEYSRQPIKMYYPIGVLFDMMKTDDFLPWTISLRTKDAPSNGANIGKEALESMFMQSLKEADYLRRKADVITSMKSEDHKQLWRGLAHDNFDEFWSVNKKLVDSSEKVAYLPIRLYKTGSPMSQIPLSPWKSPSSPNLLSDALTSLESSLDLSTHSIISHGIEVPLDTPLSWHYDRYAHRCRQFYFGGCGGNENRFETKEECDSQCQFVDNSVLERCSQPYDAGHCHSDISRHYFDMAKGACICANYTGCGGNNNMFYSFDQCMSVCGQFAKPNHIQIHDNTAEYSHGGSAPLTPLQLLHKQNAQHSSQSHHHQQRVLQSPSHHQQQEHHQRYKELLRHHGEQQKRNHPILTRPQSSHSDHAEELYEDDIGHMKQKREDSSESKTVELSIGTTQIFRHTQDGDQFVTKINGHPLVITEKIMEMVRSGRARSIDDAIDQLAASNQNLHLTATGNPAPNYVYLNEKLNPVYKNVPQQTLQQKSSSSSTYQNLPREAFIRPVDPEERRRWKEKMKKKINPVRRIEPSPSTFYDVFTTPEPVTTTTEPVTTTTTPTTTTTTTTTTTTIRSPVRVPTTSTIHRPVVSTQSSSFYQESFDLSKIRKHKEAVRNGKIPPQRPIDDYDDDRVPYETDTDSVLPTLPPTVSTTTQRPTPRPTVPSTVPPTTTRATVVLPVSREELAPAPHTEKVLPSLVYPKNNYFDLDEGKEKEEEEEYEEYEEDDDDGLDDIDHQLTITQRIEPPTTSVPSTTTTQRPTARPHRPTVPYHVPTVAPTFASRSKEAMEKPLQLIPPSFDQTTSSTTTYRPLVAVTTPRPRIAPTEPAEPTVAATRKSLWGSYESESSIFDLLREVPIDCIYGNSHTLFVIMHMNRYLFLS