lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development.
Subcellular Localization:
Secreted.
Sequence:
MWFPVTLLFLAGVAVATNNHEHAWETGNEYQYSVFGRTLAGVDKLKRQYTGIQYNGILTIQVKSPELLQAKFDNQHYAHIHQELSNGPDDFDDPKNVNYKRMPMSEKPFEIKLKHGIIRDLLFDRDVPTWEVNMMKAIVGQLQVDTQGENAINSKSIQVPSDESFAATFKAMEDSVSGKCEVLYEITPLTVNEIQAKQDRIPMPSLHSDGNHYEVKKLKNYERCQERQLYHYGFDIKSAGKKWAGQDKVISQLSVTEMVISGDLKRFTIQSTEMKNEIAVQPETSDSPIGNVYTITRLTLKKKNSISNSWFGPHEISNLESTGNLVYTFNNPFSDSDNRRVRHHSVSQNSEQENSSESSKSSSQSSSSSSSASSSSSSSSSSSSSSSSSSSSSSSSSSEEENENVVQTKAALQNIFLAPNIPLLPYFIGYKGKTILKSDKQNVMQFAKNLISEIAEEVQITSEGYEATMEKYTILKKLLRTMNRKQYAELEQYVLQFNKGSDSRANAWTTFRDAVLHAGTGPAYVTIENWIKSGQVKGAEAARLLSQLPKNVYLPTPNYVQAFFELIKSPMVTQQEYVNVSAPIALAELLRNSYIGQNYYPIYSFGFITLKKNDEVVGKYINYLANQLQQGYQENNSRKIQTYIFALGVTAHPKIISVFEPYLEHSLPASTYQRTLMVAALSDLAKVQPKLVGPIFYKLYLNENEAHEVRAMAVHEFILTDPPMITLQRIAKNTNYDTSKQVNAVVKSTLESLVHTKRSEWRHLANKARNVRYLVTSNNYGNWHSSGYHLDFQDWLVNGLSLQTIAGDDLIPKYVYVGVNSVFDFLDQPSVEAGYGLSSHRQFFNEISKQWYSHQADDERRRSRVEKLAQALQIKAKEQNNLEGHFLFNSVYDSAFYPYDRHRIREAVAALKQFLNGNNKLEGSAFNNYENIMSFANEDGLPFVYTLDAPTFTKAKVNFKQGGRTANSGTFQALIANNVQQQFGFVALFEHQKYIAGINNNRVLRVPVEYDVEFNSNNAKNFALKIRPQNLPRMGNELKLLHYSVVPFTTQQDLLDLKPTSNDKNTRPVFTSPVYKTTVQKDTFSIKVESDSIGKESDTESFVADVLRLTNANDDHYTKISTILTSDQIQKSEGHITMTYDTVTIGGNNDNSGQSSEEMESLHSISWKSNSKERRKQIANNLSKGIKSGEVYIFDVSYSVPMLHENEYVFTFGGMKSNSNQKLRGYFYWNSHAPQEVNYEVCFSHEMQYAPRATPLNFKYALKNSPRDEYKAVLKYGKTCATGNKVVITGSSSQSQQLRDIIENSSLPNNVWKRFQTGNKAVENCMKANDIAQMRDQIDVQFDLSNIVPESVRRYAKKIIEYLEKYVYKVCDNVSREEESEENTIKNTLLFASPVNRMWPNWLPQSVSDITSGWSPSFNSFGPSSESQWQTMRLNVADYPDEFESEKQSCTLDKDKVYTFDNQLYNVHLGKCKHVLLTTYPQDFHNRRNYIPENSKVAILAEDADNDSRNVYIWLGKQEIKLKKAGNNVQAVVNGQNVEISDKGYQKINGNEITFEILSLPDDSLSVVSEKYGINAVYDGKRVVISASDAYRNAVRGLCGNFDSRPNTDFVTPKNCLLTKPEEFAATYAMTQENCQGPAPENKRRAEQSTCHEFPENEQMNVISDREAGRMMTEGVNWGYHQANRNKEHGRGNKSHQNNKKQYQANSQESGSSESRNDKKKHNIVYRTRVVEEGDEICFTTTPLPACRQGARPTERYPKKADLYCMPRNDQSLDLKRRVEDGANPDFTRKSVSRMQVFQVPVSCSAA
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MLPRPFYSKTRLQNKQTDLQTTTRMVMASAICAPTFLSSPVCSTKSAIYTTSSSLASHSKTPKLHLPKAVPPLGASLFSPWSGLKHLGIISITPKSLNSERKRRGKGMVIYASLFGVGAPEALVIGVVALLVFGPKGLAEVARNLGKTLRAFQPTIRELQEVSKEFKSTLEREIGLDDISTENTYSSSKPNTANPSSTTSTEGSQTLVDPNGAPSSNRAYTTEEYLKITEEQLKASAVQQQVQTSPLGEGELETETLPQANIREAATTMPPHRETESEK
The following text describes a protein:
Function:
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II.
Sequence:
MAPEQQRDSRTAPGSDVALPDPPPIHPSFIQVAKPYIFEQTIQQCLAAMGVNPLREESLRLQGVTWIDNVRRALNLPIRTFNTAVVYYHKFRLIHHDTDYNNMDAAAAALFMACKIEDTLKKSREILCAAYNLKLPQSEHISSDNQILDEPARGIIGLERLMLESSGFDFRTRHPQKTLIKLARQYRLTPQSEVSNVAYRISQDLYRTFAPLKQTTSTMAFSCLELAGRLLEQRIKEVELGTDYARWRTSREEVMETLLDLLELYTHNRSATTVGPHFPADRFLTVRIPLNKEAEEQNLPRYTNSIDEDKLTKDSRKGPATNSSKTEKGAPTTGALHHPLIPVTANGERPKPGEKGRDAAVRFIVDSEYAAAEKTQVAEYFKVEMEEYEVEE
The following text describes a protein:
Function:
The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MALPKTLHPALTPDELAFLAEHDHISIVPLFSMTRVRLISGIYGPFRPPSASRVPLWLGLSLKKKRKCRIVPPEWLSAERLQAFLRDEKENSEGFERLPRRFMEISKVLLDIASDDLSQPTLLRSLLKDIREVRQAKIRMGLQSEDVLQNDYLQVTNLTPLELCELKPFLVRAMGLMQTLRPPEEEEDEE
The following text describes a protein:
Function:
Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis.
Subcellular Localization:
Cell membrane. Golgi apparatus, cis-Golgi network membrane. Lipid droplet.
Sequence:
MALLPTLPGAGPRRGSMPLPIKHQLVRASAVDELDSPPSSPEVGSHAGVSPAGGRGPYKVMLLGESGVGKTALAAIFGGLKGSVHHEEESTEDSYERRFCVDDEEVILILYDIWDQADPGGWMQESCLQTGDAFLMVFSVTDRRSFTRVPPIILRLRAGCPRSDPPIILVGNKSDLARSREVSREESRSLAVMMNCKHIETSAALHHNTEELFEGVVRQIRLRHHRREAAEGLAKEGAGGRRESLTKKAKRFLSSLVPRNGRFFKQRSKSCNDLSVL
The following text describes a protein:
Function:
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane.
Sequence:
MALPLQPQASFPSISSSSSTFFAQGSKLLAPKLRNALLNRTTSYSTSSCKASWQELAGVLVFSAVPFTAVKAIANSPLGESLQRRMEERKKVAIQDSSKFQALAAKARKESLWYGEERPRWLGPIPYDYPAYLTGELPGDYGFDVAGLGKDSVAFQRYFNFEILHARWAMLAALGALVPELLDLLGAFHFTEPVWWLVGYSKLKGDTLDYLGIPGLHLAGSQGVIVIAICQALLMVGPEYARYCGIEALEPLGIYLPGDINYPGGALFDPLNLSSDPVAFQELKVKEIKNGRLAMVAWLGFYAQAALTGKGPVQNLLDHISDPFHNNLLSVLNFM
The following text describes a protein:
Function:
Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to centrioles and to the distal ends of basal bodies.
Sequence:
MLGQFSPGEPYTTSLSSTPPWSPANQFQLFRFRSRTEPIDWRRLSTLDVDRVARDMDVSVLQDFIMTVTFCALEGERCPNCRGPVDPSLVKLLRMSQLSTEYLLQCQDFLSSQLAGLEERLQAATSLVQQGEGQRAELEKSLQETKQENRRRKQLIATQQLLLQASANNYHKCQFCEKSFVNYSYLQAHVQRRHPEVTDAEKQKKRKVEEMEDGIEELKEKLRLTQMQLQEEQQADNLRRQQEQEQQRRREQSEKEALERWKEDERRKFNQEIADLRQLFLQESKEMASKSSSIEAKLLVLQNKEMAGFNNASLQQDSDPEKEMRENRERELRERIARKKSEWRRKFQEAQKRHQQENKELKSENSRLLKALSVEKNSTSSVQKLQQQVVSLSSQLSQKDRLIKSQEEKIKKLSATPVPVSVVSLNDQDSSEEPVEQDRDSQEDSDEPQWKAPKIRKGKPALMRESKPILEESLEQKLENMGLRKGTKGISKQTFKSLSSLLAGQRLQKFRQQTNLQSLRDSLTLEVTRRVKSLQKSSGKPTPNTLKQRGKKTSTPLNEKSLRFRQDSKASDRREKSQQPKTLLPTPTPRSKAPPPNQTPKILAKKNSTPPFSSDEESVEDTAYITSSRGNLSSSVRVVQSGSLLNPTTEPDWTDSELSEDLDLPKIYKTCNPQGSVVQTLTRSLERQLSTPIKTPVGGTRVLPPSSTTPRPAIVKQQALSGEESDSELSSIEELTGRRAGGHKSLEVDRTSGTSA
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MVLDGDEYKEDERTKISVTHLSMNIGKLISNAYTSKLYKAYINSLGAGPLVSKKSFRDYLKEFLEIDKQSVFKTSEFCLRLSGKLIDIMCSCNILEVKVITSNDGKSSMAILRLTDEIEKKQNNQNPIAILPINLPMIVSPKKYSKRELGGYLLNNEDNEIYWAINNMMATPFKINKDLLNYLLKYNHLHRLLISSDYIHPLANIKRNKRQEREYQQFLSKVMLEKHILLIANIFSNVPETYIPLRLDQRGRIYPTTAYFHYQASELAKALILFARPDTIKRTNREAIEYLKAYGATCHGNGLNRKFYTIRLEWVENNWDRILDFENNKLFLEADDKYLFLYFCFEMRRLNNFLNNEFMLEFKPNLPIQLDGTCNGFQHLALSSNETSIFDKLNLGSSNKSKDPLDFYSHIVSLKDLLVHWEEYDVKVSTLTKEEEEESPDSQKGKEMIKELEEQIISIKRVQALGINRKTIKPVIMNKPYNATNRTLVSSIKGILAWDHTDEHKVLGDPDNLELDGNKKPRVDYTTWYKIDQGSNNLVNYKDIELLVKNIEEIIHVKYPKIKFLTNYFNEIGKILNKLNLPITWRLPHGLVVSQRYMKEHILKIKPFTYLSNSLSLSITDKIKKDKNKQLLAFRPNLVHYLDAATLTLLYVSLAKPTNQKDTKYIDLLIKRLRTVYINTYSDKGYIHKFDEDIINTITITQGESKCKYSPETRTIYINKKKIVLPDLSEFLNVPNKERVYERLSKSIFLVK
The following text describes a protein:
Function:
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
Sequence:
MKKYLIAPSILSADFARLGEDTAKVLAAGADIVHFDVMDNHYVPNLTIGPMVCKALRDYGITAPIDVHLMVKPVDRIVPDFAKAGATYITFHPEASEHVDRTLQLIKESGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPETLNKLRQVRKLIDDSGYDIRLEVDGGVKVENIRQIAAAGADMFVAGSAIFNQPDYAAVIDAMRNELAMAANG
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MASSAPIAISFLVDLTARKSQQELVRLLAVTESQSQYERKQALQQYAHNTLARLLRLLSLLRWSTRYQKALTQMTTRAQGSHQFVVETADILVQQAQELLPVGILNAETPRPLHEACLQCAKLAARLQLQVLAAKAQRLMQGMWAGVVRLTENKNERLKLEFWPGFDEPQQQVSVLISGTELDDDQHLSVTVHPALRDVETDRLIKPHIDLASLDPLELVTTIWAQLWRMKVTRLNAIFSTCASRLARPLKVTLCSDVPPQPNVAQGPWLELAFADAQSATLVIRLRPLGNGTMTLSWASSHVPTDVDIGPLRRALNDVTRQTETVLQPILNELYADLLATAERQRLSDNSRFHFYPTPPYSSSAFWPPAKAKVVGVLLAPFHAHVAVGTTLDLETLQLACHLLLAQPVAERELLAGRRMGPSTPSVGASVNMDSGTKADGSVPALPPSTAEWLLTDPLSIALHFSHVAKEPFNSGFAHVQSLLEALPIPSSSLSDDARALDAVLEPLVGLTAVCRQLSLLSVEFAVHTLPSGHLVIVIKDVPREAASGPILASTCCTIALGADGSSCFEILATNGNSYRSPPIPAAAVVSKLEPTARALSLLAEVNRVMAKKQLPFLSGEMVPSQAKLRFRMDLEDGQVVGAQPWLTGELGLDQKTQALGLQQLCFADKTPCQLPSLSLLEEFCNTSGGFGKCMYALHRTANVMTAVQQTIEAGLEVLMVTPTRFCLYDNLLGRHGIEVAVRSDNMVVIRDLTGVVKLNSQLTGVSPVMGISVSGSPTHFQSPRREDLVQTVKRKLLRLHELLDCHENKEALYFVNTDVLLRLLAAPDAVSPLACHFGACRIAEGLERFASFRKVDCEVLKSHREGSFAVKYRVTHGREVGREVDWSYSQDSCAATATIKSLSPDEASFIAFCQKKCLFMTAKPSEGDALRLSAARSNGLFFDDVWNRRGDALSQDIEAVSCIVELDQGDGKSCIVPLTLQVGQRVVPWAAKKGCTPAVAQYLRRLQFLIDDLSEVDAISLPAAVKALRQELVR
The following text describes a protein:
Function:
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with tbp mediates transcriptional activity (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSNSIVGEVYHHVILDVIANSRSDFEENGVDDATLRELQNLWQSKLVATDVATFPWAQAPVGTFPIGQLFDPVSGLRTDSLDVTAPAVANSPILNNIAAIRAVQQMDTFAQQHGNSNYYSPPTPSLPQSATNISFDSSAIPNVQSNPNNTAPFPSYSSNSLQLPTNQTADSPIINDHSTANVTSTGQEHAPDSSSTNSFGGLLLPNQNSPKKSELGETESSNTTPANSRNDVPQTDGAIHDLDDAGSPSNFESNRFAIAQKADAEIYEVLKKNRILQIDGTIEDNEDEKKPPVDTPSDEAINSDLDDPDSDEAPETEEGSDIGQAIVLCLYDKVNHHKNKWKCVFRDGVVGVNGKDYLFFKANGEFEWI
The following text describes a protein:
Function:
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
Sequence:
MATPEKAAAVAELTDKFRSSNAAVLTEYRGLTVAQLKTLRRSLGENAQYAVVKNTLTKIAANEAGITLDDQLFAGPTAVAFVTGDPVESAKGLRDFAKDNPNLVIKGGVLDGKAMSADEIKKLADLESREVLLSKLAGAFKGKQSQTAQLFQALPSKLVRTVDALRAKQDEQGGAE
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MASTNNERDNMKHNDGSTELVVSGMANSSEPLSTPDASKAISTFSVTPERMLDLLDPKNPELYLEWGKAAGLAKSLQTDLKNGLAKDSSLHQDRLDFYGTNSLPEPASKNIFQFMWDALQDKTLIVLCVAAFVEMAIGIYKFRFAPIGKRDNLGLIDGAAIVVAVLIVVLVGSISDYRKQNQFRQLSDFSKSLSETKVVRDGETIFVPTEDILVGDIVMIETGDIVVADGVLVEGFQVKTDESTLTGEPNSVNKDLARDPFLLSGTKVVNGVGRMIVVATGINSLNGRSLLALEVEPEATPLQEKLGRIADMIAKFGVIAAFGMTVVLLISYFVASPPAGKDSFQISQDIVALLILAITIVVVAVPEGLPLAVTISLAHATLCMLKDNNLVRHLAACETMGNATTICSDKTGTLTMNRMTVVEGVMLQVDFKHADIPETLKKSIFSNVTVGAVEKLLGFIAMSLNVNSTASESKDKEGVLCFNGSKTEVALLEFTRLLGFEYQKDRDTAKLVAIQPFSSDRKRMSCVMRIPVNSDLENQLGLAPNEMSSSDATTKDWVCIKGASEIVLGLCDRYVDANGKVQPLTEQDRAHYTELISSYASNALRTIGAAIRPLQIDDRTTANGKSDLIPSGDQAEEQEQSIPDDSNLILIGIFGIQDPLRPEVPAAVASCQSAGIVVRMVTGDNIQTARAIARGCGILTADGLSMEGPKFRMLTEAEMNDVLPRLQVLARSSPLDKQILVNNLKRLGETVAVTGDGTNDAPALAAADVGFSMGIAGTEVAKEASDIVLMDDNFASLVKAVIWGRCVYDSIRKFLQFQLTVNVSAVLLTIITSFYTTVSGPKTVVSVLSAVQLLWINLIMDTFAALALATDPPSPDLLNRKPSNRSESIISPDMFKMIVGQGVYQIAVCLVLFFCGPKWWGTHTGSIDEIEAIKETGVDITTASIIFNSYVFCQVFNEINCRSITSAEKNIFRGFFANKMFLGILALTIFLQAIIIQFVGVIFKTSPNGLTGVGWGISLLVGSGSLIVGFLVRCLPDFPLPKFLYPTQPKKTGRGVDGSIVDTPVTVTVTKPSLDGFRPDGTAGAIMPASDKDSYTEKLIVTGADIPVKIHGEEKEEFGALAIGDSDHLNSVTERNNSRQLWNSAIKKTRIQLRVVGHFTAPAGSRVRAMSSGKYHFTSTAPPELSSTFGSLHLPATSATPSGVSMRSPPLDSTFNTASAFLSPGMGGSKIDSTTADSAGADGKQGSYFLDKHTAEHSATQSASTAPTSSSSQWLTVRDLVRTVSVVNAFRTGRSKRIDFTTLQVVDVNSIRRTRAIHARQMIASRASHLPPNSRAPAVKSSIDAGSNSGSVSGSNRLA
The following text describes a protein:
Function:
Involved in protection against replication-dependent DNA damage. May act by restoring active replication forks, repairing unusual DNA structures, and/or preventing aberrant DNA rearrangement at arrested replication forks.
Subcellular Localization:
Nucleus.
Sequence:
MNSFLLLDHVSDSQDSGSEWSNTHGSLISQRGNEYDGITPATKEKNQNKLEILNNETTIGSTKSSVSSLPELNRNVSFEKSDQNLAETKREEENKRTEVFKKDAEHEAVVVKRDFRPRRPEQTRPYTYDFLRHQIEFKRIGLVPITVPHGFSSDRSITSKSSHKPVNVIVRNRASSRKPPLTSTHRFRRYGAVISDSDDDESNTEQDHSKESNLNTADNDLALSSTIEGKKTSTSKEALESESLLSDSDQSMTNISSNSTVSDLNLKTLKKRLRGVLPPSFLTLQEKKKLENRGVKKKTSLHKSVIEGEKIKGVARRKLHPRSTAKLSSELGNEISDSDNSISTPTPTDDSRFDTSEFLDSISRDNGWLKEDVVDQLWLPKRSLSALKKSSSLTSENPFQLNVAANAVSTIPVYRTTKTKMKKNRFKYVEVEKLPDLILESYGKKAPKFLRVFARSSSHIPKMIRRKRQMDSKKYFSFDKESDRQVIDQVLSDWYSGKHELVQQSHSYKKPSDSKSVGGNIFSVNSKKHSVNINAKTAANNGLSHLQNFSEELLKKRKLFSSLFSNNVSYKKSKKLKRTHTVHDKCQKVAKLDHYIRDNIELNSKEREHDCYEGTLAVPQVNTEIRKSSRKQKAQRFIRDDFDTVFFQSSSNPNYFTDVNPFWNIGIWSTTFNVITFRPGLSLPNNSFIKTQGLNSILQLDIVTHPFKSVYAFSCLFNIQDDVFKTFEKLKDTFETVLENLPYFTNSETVDLYNLLSFCSAFILHSQVSMGLVNLASSFLETYALVNDRVSSISGLNRSQLVEKIAVLFQTFQVVFYCEFELGNQQNINKVSWLASDLISKLLSAGQSGLLECYRNLRIQASDTTVIDTLFLESWSILNHILFHVYKKKYALWEQVNSFFDLQKKELSILEMEKIWYVIMTLNPVFQIGLNGTTHSPGNNSFWPLIIRVSESAFKMHKDGHNVKVVERYLRTVFLRIHFLISEWRWEDVAQILFLIFDFFSHRKFNDLSSEISEDTPTDFPDFVKSLDRPPNLHVTALDTCFVIYLKVILISISRLRQVDENTNSIKRIVSRLQPLHSRQYTRESPFSIKDFMSLEHTHTLLICLYWAAPENCRPSLNRIRDIVIVDNSHLKARLISLKAWLHLMKYVIKEGTDYELAQGMEWFNSILKVTFDEYLALFSNGTSVGEMQLAEYSKHQLENALIVAFHSLQDLIPNSSVYISRINVLVTEQSCRRILKDSHFFPPRVTLECILFLKKFLQYQSNTEPPKVTVVGSTSHDSQDAYFDSDVLDDNTLILEQEKFERKYEVAQILRTFVSPFLYQTISYLVGNDEDKENYIRILLLPLMECMAICASFAVEAKINDWSYYIDFGSESWERIRNTPLKRSLSTTFYSFLISYNDSFIKKHEEKVLTVWFESLGALDEDHAAQFTILLLQKNLKNPILLNLPISVKIEEISINYFKSVHLNLLTAVFCNMAKLYADAKTNGFASSQYLQSLFIHYLSSLLSSMQHSYETNGHSSDTHSLFVINSQRVVGDILQYCSQFANDRNLPALRYFMDSTKFPQPPERLEYTALRLRSYARKTLTNSASQNALFSFLKANFDVALLEQKQTETSNLLRLAMGFHNQNSSSKWDVEISSLRKFCVKELLLSYLGEGSLAAMFYSLLLLEGLSRTYNSFRRIYLQPYIQQLLCEEISVFVADLEKYALLYENKRPLLSGRIYYLISSFVAISMTNKTSGLPSSLICNLQNFLARIARDFLLELCWNIEGSEFPPPYNTVDCRSKFVKTIQQHCSADWYDNVTNIVHKSRKKKLVLPSQVEQEEEYWSGLMEVTIQIWKHDKGFLEPELDRFLNVICSYAPDMSGLPTKIKCFLDKIGYSWMTEENDFDIVLF
The following text describes a protein:
Function:
Required for efficient pedestal formation in host epithelial cells during infection. Acts as an intermediate between Tir (via host BAIAP2) and host WASL/N-WASP. Directly binds and activates WASL/N-WASP, which stimulates actin polymerization and leads to the formation of actin pedestals at the sites of bacterial adhesion.
Subcellular Localization:
Secreted. Host cytoplasm. Note=Secreted via the type III secretion system (T3SS). In host cells, localizes to the tip of the actin pedestal.
Domain:
The N-terminal 21 amino acids are necessary and sufficient for translocation into the host cell. The C-terminal region, composed of several highly conserved proline-rich repeats, interacts with the SH3 domain of BAIAP2 and BAIAP2L1, and the GTPase binding domain (GBD) of WASL/N-WASP and WAS/WASP. The N-terminal translocation signal and two proline-rich repeats are sufficient for triggering actin polymerization, but each additional repeat gives higher activity.
Sequence:
MINNVSSLFPTVNRNITAVYKKSSFSVSPQKITLNPVKISSPFSPSSSSISATTLFRAPNAHSASFHRQSTAESSLHQQLPNVRQRLIQHLAEHGIXPARSMAEHIPPAPKWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPXWXAPTPPVQNEQSRPLPDVAQRLMQHLAEHGIZPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLXQHLAEHGIQPARNMAEHIPPAPNWPAPXXPVXNEQSRPLXDVAXRLMQHLAEHGIQPARNMAEHIPPAPNWXAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS
The following text describes a protein:
Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Domain:
Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.
Sequence:
MDPNCSCSTGGSCSCATSCTCKACRCTSCKKSCCSCCPAGCAKCAQGCICKGASDKCSCCA
The following text describes a protein:
Function:
Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MASPDDPLRSDHMAKEPVEDTDPSTLSFAMSDKYPIQDTGLPKAKECDTVNSNCPPNSDDQPQGEENDFPDSTKDPLSGVSRNQPCKDRKGSCSCPSCSPRAPTISDLLNDQDLLDTIRIKLDPCHPTVKNWRNFASKWGMPYDELCFLEQRPQSPTLEFLFRNSQRTVGQLMELCRLYHRADVEKILRRWVDEEWPHRGHSDSSMHF
The following text describes a protein:
Function:
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTKSLSELLEELTPKRVVEELNKYVVGQEEAKKAVAIALRNRWRRQKLPENLRNEVIPKNILMIGPTGVGKTEIARRLANLIKAPFVKVEATKYTEIGYVGRDVESMVRELVEVSFQMVKQEKMKEVRERARRLAEERLLDYLVPHQFTSFGIRESRDAGKREELRQKLRKGELDDRIVEIEVKEKTVPMVGIAGPPGLEELENQIKEMLSGLIPSKRRRKVKVKEALQILEQEEAEKLIDMEEVAREAIYRAENFGIIFIDEIDKIAVKTPGAGPGVSREGVQRDLLPILEGTTVNTKYGPVKTDHILFIGAGAFHMAKPSDLIPELQGRFPIRVELKPLTKEDFKRILVEPENALTKQYIELLKTENVYLEFTDDAIEEIARIAEEINTKTENIGARRLHTVMEKLLEDISFNAPEMAGQTIIIDAKFVKAKLENLVKDEELSRYIL
The following text describes a protein:
Function:
Upon binding a putative inducer it probably interacts with TorS and allows it to play a role in the induction of the torCAD operon for trimethylamine N-oxide reductase.
Subcellular Localization:
Periplasm.
Sequence:
MRVLLFLLLSLFMLPAFSADNLLRWHDAQHFTVQASTPLKAKRAWKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWGAEAILLGSSTTSFPDLQKQVASLPVIELVNAIDAPQVKSRVGVPWFQMGYQPGRYLVQWAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQEMLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASDQMVWQGELAVEQAIRQLQGQSVSDNVSPPILVLTPKNADREHIRRSLSPGGFRPVYFYQHTSAAKK
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Required for proper complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MASTAGTVIKSGVKQVRPLLSVDNAEARKRVLNLYKAWYRQVPYIVLEYDIPKNESQCRAKLREEFEKHRHAKDVRVIDMLVVKGQMELVETVKRWKQKGHVMNYFRTPINPKPNDFLSKFIAGSA
The following text describes a protein:
Function:
Component of RNA polymerase I core factor complex (CF) that acts as a SUA7/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment. After binding of UAF (upstream activation factor) to an upstream element of the promoter, CF is recruited in a SPT15/TBP-dependent manner to form a pre-initiation complex.
Miscellaneous:
MISCELLANEOUS: Present with 398 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
Although it shares weak sequence similarity with SUA7/TFIIB, displays a similar subdomain organization as SUA7/TFIIB, with a N-terminal zinc finger, a connecting region (composed of B-reader and B-linker regions), followed by 2 cyclin folds.
Sequence:
MSTFIRGPICGTDNCPSRLWRIIDGRRTCQYGHVMEGDVEFNDDEDDLNGLGAGVITRRLNLTTNATGSFQSSQLTNSQLLQQQQRQSHKKFKKLIGHEAKLLFLKSFQFILKRQIRWLITEMRFPKEFEHVAKIIWLKILKTINDQPQEELKLQLHMTSTISILYLASTHLSLPVYTCDYIKWICTAKMPYFQASEILPKSWRIQLPNYYVSILEGSISPFNGQLYNKIALTCGMIHFKEFFNSEISCQGLLLKLVMQCALPPEFYFYTKQVIEFEETDIRNLTLWERTDERHTGRVSNHAELRVLSYFMLTINWMLSFDRDRQYPLKWILSLTESLTQRTTTSESIGRNIVKVVYPDKPTSSDYFQWSEEETLEFLKWMEKQFLPTQTKSLHNENGSMEMTIDQKIARRKLYKIFPLDREANHDGEFNDSTHQLTFIEDLQERYAKQTPFFESNKIRDSLNYQEANPPARKEAIGRLLTHIASQLLVDFAISKEQLKDCISRIKNACLHRMN
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
Sequence:
MSSKLKIFELLDVLDNLKHLKRTGWVKCGVTEPETVACHMYRMAVLAMALEGEIDNLDAMRTVKMALVHDIGEAIAGDITPHCGVSDQDKFDLEKKAIDTIASYVPNVGDEWTMLWKEYEEAASLTARVVKHLDKFDMIVQADKYEQTHAIDLQQFFTSTTGVLTMEPFATWDRALREKRNQRINKE
The following text describes a protein:
Function:
Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast. It is thought that it phosphorylates the STE7 protein kinase which itself, phosphorylates the FUS3 and or KSS1 kinases.
Sequence:
MSHIEFLERAGCSQYADLFEEYSLTDINDLMHIDRDILLEIGVKKLGDRIRILKESKKLQEPKDDAKHVQQLQELISNISELSTTSTNINEEVITERHCVIFILNDGSAKKVNISGCFNADSIKKRLIKRLPSNLLAVNTDGQTTQESSDYDVFIVDYSKNVLRLLYDIELVTICHSNDRVEKNRLIFVSKDQTPTDRAINASKKLYLKTITALNHIESYYDAQSGMPNTPVTQDGTLRIHKEGKDKLRKIFDQRPPSEFISTNIAGYFPHADTKRLEKALRESYRQSARISMKSNNSRHISSESNRVGDILLKHSNAVDMALLQSLDNNNAPSSKPEVIPPSTPQEEDNEGKIKLMEETESIDDYYMNSDEEHGTVSLPTKIVTPKNWLKGARIGSGSFGTVYLGMNAQTGELMAVKQVEIKPAIAATADANVEDKNAEKNVAKAPSTNLHRKMIDALQHEMSLLKELQHENIVTYYGSSQEGGNLNIFLEYVPGGSVSSMLSNYGPFEEPLIVNFTRQILIGVAYLHRKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNQENQDKRTSLQGSVYWMSPEVVKQTATTSKADIWSTGCVVIEMFTGKHPYPDFSQMQALFKIGTNVTPEIPSWASPQGRDFIRKTFELDYQRRPTAIELLQESWLESHII
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
CVICLEDVQDADIYTLAECSHKFCSSCVKQHVEATVTTGRTFPVACPQVECTKKFTEGECKKLLSEAALKVFMKKIEEERIPDAERVYCPYPKCSDLMDRRTFLDPNPRKLCGACHRYFCLDCRVPWHTFSTCAGYQRLPLDLKDAADAKLYRLAENQNWRQCKKCRWMIELSEGCYHMTCRCGYEFCYTCGMEYR
The following text describes a protein:
Function:
Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
Subcellular Localization:
Cytoplasm. Endosome membrane. Note=Interaction with PIKFYVE and subsequent phosphorylation recruits it to the endosomal membrane.
Sequence:
MKQLPVLEPGDKPRKATWYTLTVPGDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANPNRSFSDVHTMDLGKHQWDLDTCKGLLPRYEHASFIPSCTPDRIWVFGGANQSGNRNCLQVLNPETRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHWTLLKFDTLLPPGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMSHSGDSHEESQTATLLCLVFGGMNTEGEIYDDCIVTVVD
The following text describes a protein:
Function:
Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MLRSLVFVAPLLVWGHDIKGFDDTVLFDIHWPGENTDFANAENMIVTTSHQEKYRCILPNIQEKETSSEEKYEGPTALEVISPLFTQSSCTYRLESYWTYEVCHGRFIRQYHEDREGKKVKLQEYTLGRWDEKLYEKMLSQAKEAEKDKSIQVPVKKIDNVNLPYVEILMGNGTQCDLNQNKPRETRVLYVCYIHGKHEVYSLKETSTCQYEIIILSPLLCSHPKYKPKETGENKINCVPLDNSPPQPYNLAKMKIESTKLRRKSDLDRIKIEFVPPPDFTDKEEVSKMPETKPHDASPVQSFLAGKNCLTGGTGWWRYEFCYGKSVEQYHIEKDGSKVTIKLGTFNKQKHIEWMEQHPHKRPKPLAQRTQLSHFYSEGTVCDKTGKARQTEVKLKCLEDSTSLNTVSLYLLEPRYCEYILGVESPLVCDILARADENGLIDVGEEEGDELPTVNIRL