lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the cell wall. Required for anaerobic growth.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Sequence:
MSFTKIAALLAVAAASTQLVSAEVGQYEIVEFDAILADVKANLEQYMSLAMNNPDFTLPSGVLDVYQHMTTATDDSYTSYFTEMDFAQITTAMVQVPWYSSRLEPEIIAALQSAGISITSLGQTVSESGSESATASSDASSASESSSAASSSASESSSAASSSASESSSAASSSASESSSAASSSASEAAKSSSSAKSSGSSAASSAASSASSKASSAASSSAKASSSAEKSTNSSSSATSKNAGAAMDMGFFSAGVGAAIAGAAAMLL
The following text describes a protein:
Function:
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
Subcellular Localization:
Secreted.
Sequence:
MGTQSNPWTSVVLLLALMHKIAALSNTQACNSAAGDSFHNYGAKTINGTQFIPFSHYAGKHVLVVNVATYUGLTFQYVELNALHEELRHLGFTILGFPCDQFGKQEPGENNEILSALKYVRPGNGFVPNFQLFEKGDVNGDGEQALFTFLKNACPPVGESFGATSNRLFWEPLKVNDIKWNFEKFLLDPDGRPVMRWFPRVNVSEVRADILKYFHQLLQTAQ
The following text describes a protein:
Function:
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
Sequence:
MAPEHKACLIVIDGWGIPSEESPKNGDAIAAAETPVMDELSKSATGFSELEASSLAVGLPEGLMGNSEVGHLNIGAGRVVWQDVVRIDQTIKKGELSQNEVIKATFERAKNGNGRLHLCGLVSHGGVHSKQTHLYALLKAAKEAGVPKVFIHFFGDGRDTDPKSGAGYMQELLDTIKEIGIGELATVVGRYYAMDRDKRWERVEVALKGMILGEGEESTDPVKTIKERYEKGENDEFLKPIVVGGDERRIKEDDTVFFFNYRSDRVRQITQLMGGVDRSPLPDFPFPNIKLVTMTQYKLDYPFDVAFKPQQMDNVLAEWLGKQGVKQVHIAETEKYAHVTFFFNGGVEKVFPLETRDESQDLVPSNKSVATYDKAPEMSADGVANQVVKRLGEQEFPFVMNNFAPPDMVGHTGVYEAAIVGCAATDKAIGKILEGCKKEGYILFITSDHGNAEEMKFPDGKPKTSHTTNKVPFIMANAPEGWSLKKEGGVLGDVAPTILAAMGLPQPAEMTGQNLLVKA
The following text describes a protein:
Function:
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein.
Sequence:
MSVNSTMEDNPPQNEHLVGTPATTYLISQGGQYYPLYNNNTSGYQAQAQARPCCHGALERAPNTAKYDDMNLYSLKPNVKVDFEETFQEPLGSENVSVVWNYNKVIFNWTSRGFYIFLSALLGPILGIAWGLVFAIMNFILVWLVNPALKVILQACRIVEVLARGVLRSSLDPLFQSIGQTFTSVRGNFTLTVPGLDGPGLKKESDKLKLPTLSHSHI
The following text describes a protein:
Function:
Can suppress the synthetic lethality of the hal3 sit4 double mutation when overexpressed, suggesting that it is involved in the G1-S transition.
Miscellaneous:
MISCELLANEOUS: Present with 2200 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MDTSNHNQDHDSHVAAQRENDNNYMPPSPSMSESSMIFERNVEDPSYLYKTVSNNAANSLSRQSSRTSLFNHNNSSNRNFHNLSQRSSAVNLHLQPSRTNESIASYQTYNPDFVVQTPLDHRRTLENFVPPALDAGCSIVTDDTTGLDDVDMVYSRRPSTIGLDRALGRTRSLSSQSFDNETSPAHPRSPNDHGSRLLRFYSYADMLSDDNNNNVSNATSTSSTANPLRRPPMQGHYSFSSSLLNSPSHLPSPPSASASPPQHMNFTNPFIISRRYSNTTINNANGGTSAGSTTGAALSRSPSNQQYLLKQQRSPSGSARSRRNSNRPGSAANIMIGKPKSKFHMESSGSEGFSSEEEDNTMIERDKLNLKQKLQSQLAQPPSIANMVNDNHNNTNKHKNTINNNIKNSPAFTNSNPSSKSNSNSTITSMNPDTTK
The following text describes a protein:
Function:
Probable E3 ubiquitin-protein ligase that acts as a regulator of double-strand breaks (DSBs) repair following DNA damage. Functions in a non-canonical fashion to harness RNF168-mediated protein recruitment to DSB-containing chromatin, thereby contributing to regulation of DSB repair pathway utilization. Once recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168, competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby favouring homologous recombination repair (HRR) and single-strand annealing (SSA) instead of non-homologous end joining (NHEJ) mediated by TP53BP1. E3 ubiquitin-protein ligase activity is not required for regulation of DSBs repair.
Subcellular Localization:
Chromosome. Nucleus, nucleoplasm. Note=Localizes to sites of double-strand breaks (DSBs) following DNA damage. Recruited to DSBs via recognition of RNF168-dependent ubiquitin products.
Domain:
The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif also mediates interaction with ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
Sequence:
MAAAGPSTRASSAAAAAALSRRGRRGRCDETAAAKTGAPGPASGPSLLVLSPPLLQPPLPPRPEESGCAGCLEPPGEAAALPCGHSLCRGCAQRAADAAGPGCPRCRARGPGWARRRARDDGQADSEVLGECARRSQPERCRPRRDGGAAAAGPRPEQEPRAAPAEPDFIFRAPIKLSKPGELREEYESLRKLREEKLQEEKPSEDQIHKLLPEDTETGKRKMDEQKKRDEPLVLKTNLERCPARLSDSENEEPSRGQMTQTHRSAFVSKNNSYSLAFLAGKLNSKVERSQSCSDTAQERAKSRVRAVPGNKAKVTTMTPASNPIIGVLLSTQNNRCVSAPDLTIEKRLPFSSLSSLASLHKPERSVSPESNDSISEELNHFKPIVCSPCTPPKRLPDGRVLSPLIIKSTPRNLNRSLQKQTSYEASPRILKKWEQIFQERQIKKTLSKATLTSLAPEMGEELLGSEGIHSSKEKPLVAVNTRLSGGQVLSEYTGPTSADLDHFPSVSQTKAEQDSDNKSSTEIPLETCCSSELKGGGSGTSLEREQFEGLGSTPDAKLDKTCISRAMKITTVNSVLPQNSVLGGVLKTKQQLKTLNHFDLTNGVLVESLSEEPLPSLRRGRKRHCKTKHLEQNGSLKKLRQTSGEVGLAPTDPVLREMEQKLQQEEEDRQLALQLQRMFDNERRTVSRRKGSVDQYLLRSSNMAGAK
The following text describes a protein:
Function:
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity).
Subcellular Localization:
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSFFGGNKKTPEQELKDSKRELSKGQREMDRELNRLKIVEQEYIGKIKQLAKAGRNDEAKRMANDLVKLRGQMERMRATKTTLSAVSTKTTTIKANQTMANAMASATKAMSTMNKQTDLVQLQKTMMEYEKQTQRVEMTEEMMQDMFEDDEVDEEADDILSKVVDEVCLDNYQKMPSVAQKDLPYSSKTSTFKTEDEELNKLLQSL
The following text describes a protein:
Function:
Transcription factor involved, among others, in the transcriptional regulation of osmoprotective and inflammatory genes. Binds the DNA consensus sequence 5'-[ACT][AG]TGGAAA[CAT]A[TA][ATC][CA][ATG][GT][GAC][CG][CT]-3'. Mediates the transcriptional response to hypertonicity. Positively regulates the transcription of LCN2 and S100A4 genes; optimal transactivation of these genes requires the presence of DDX5/DDX17. Also involved in the DNA damage response by preventing formation of R-loops; R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus.
Sequence:
MTLCTIPTVGVRSQVRERRPGRPPSGKRLAMVRDMPAKVRSAFRRSLDPCDNSNDSGLGFDHHADPLHLNSMSERLTWNGERAEPKRLKMDIKLENEDVNDRYCFPDTLRSCKDSTTLIRTAPAGSIPSLSMNNNQTSSSGRAVPRCIPLSNRQPSSSPVPLTTQLSTTSKYASEVSLTIVKQPEQQHRARYQTEGSRGAVKDREGNGFPVVQLVGYYQPTTLQVFIGTDVGKVAPHMFYQACKVSGKNSTPCVEKKIDGTCVIELQLDPSKEMSATCDCVGILKERNVDVEHRFPDQLGNRSKKKSTRCRMIFRTTLTHDDGTVETLQVCSQPIVCTQPPGIPEICKKSLTSCPASGGLELFVLGKNFLKDTKVHFQQIDDDRHIRWEQAVVPDKEYLQQTHFVCVIPPYRRPDITEPVTVRLCVVSSGKTSEPHQFVYTPVNGAIPSVHVDPPPATTQAPFFNKMLWSSNISKREQDLGMMPPPESSLVPMASRRPSISLPSTSDNLSPPLRTLKQEYIDENSQGSIDHSERYRHISESSLDVHPGDSNMSMINENSIDMLSHNNMINENSNMSVSNDEIMVRRGSISRSVCENSMDVNLSNSQMSDNSCSNVMQHCSNSVVTDRLVLSQPVLMQNMLVSGATAEELKVMDLRMKMPMATVADLGNSSAPSMATLQSFGVTEANNAPLPAQSAQSVENFLTNIEATKALSSDFQIKKDKMNEIISPFRRNNSTEPVFLSSQRPFLSGTSESENLLVAKSEAAAIAEQTITEQASAITTISTIENVVTTEKLDQLVNSTVESHIGSPTRSEPVNKTSSDDVIHDVMLNSRSSLMVAPMINTTLPPMNHDLNQNSANLSPAVILNSQISPSLMCRNAPEALLQPNVTVEAHTSPLHSPVANPLSLTADPEKVVLFKAAVDLLETQKKISELDSRKAMESKEPMMNKMMMNDIMTTCTSNDVMPSSRLSQLQGNNFVPQAPLLNTVPTIAQDNKSDFVIPVPVKEMTGVADKKNEDRMIPQSFTSLTENELINLINPSCFDQGNNSNYH
The following text describes a protein:
Function:
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
Subcellular Localization:
Cytoplasm.
Sequence:
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDRRHIQNEDVLKLLEISPLPINIECSINAEITDFLCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRAYHNKGIEVSLFIDPLKDALHFAREHQVKQVEFHTGVYANLHNALYSNANNQIHAISVLKDKSPKELKEELHNAFLQLRRMSKEAFFMGITACAGHGLNYTNVKELLKIPSLRELNIGHSVVSKAVLVGLEKAILEMAQLIKR
The following text describes a protein:
Function:
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Plastid.
Sequence:
MALRLASLKRAAAESCRIFETRSFSNVAAMPSPFNSVIDRPIGTPPLISPEFDQNQSQPGSIDENRFGFGFPSFAFSGSMDLMAVPKKKVSKHKRGIRNGPKALKPIPLIIRCSFAGSFSEKATRTIRRFSPQLAAKMRPPLAPVIRGRPSAKRAIYICGQPRWVFVLISSLVSFALWYISCGLFTVSLALLIGLLATILHATLRTPNLKARLNTFREEFRAVWRNYSEI
The following text describes a protein:
Function:
Transcriptional repressor (By similarity). Involved in pharyngeal development and required for the formation of the pharyngeal isthmus. Plays a role in modulating cytoskeleton in the muscle cells of the isthmus. Regulates expression of the acetylcholinesterase genes ace-1 and ace-2. May regulate its own expression.
Subcellular Localization:
Nucleus.
Sequence:
MDQKFYISSLLQEDTPSKEKPETSSESPIPTGSECSLNESSDTTLDQKMEPNKKMFNGTLDFNPWICHVSQQLAAQLSQNGKNRPGAPNQVPLLNMNVNQTMGNMWDPRLSWLYPYMSKSPQKRKGGQIRFTNEQTDALEHKFDSHKYLSPQERKKLAKSLSLSERQVKTWFQNRRAKWRRVRKDGEDEDEMPNGASARSLGQLQSSNPFLSHG
The following text describes a protein:
Function:
Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth. Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (By similarity). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (By similarity). Phosphorylates ERO1A, enhancing its activity which is required to maintain endoplasmic reticulum redox homeostasis and for oxidative protein folding (By similarity). During endoplasmic reticulum stress, phosphorylates P4HB/PDIA1 which induces a functional switch, causing P4HB to change from an oxidoreductase to a molecular chaperone (By similarity). This is critical to maintain ER proteostasis and reduce cell death under ER stress (By similarity). Phosphorylation of P4HB also promotes its interaction with ERN1, leading to reduced activity of ERN1, a key sensor for the endoplasmic reticulum unfolded protein response (By similarity). Required for osteoblast differentiation and mineralization (By similarity). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1. In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (By similarity).
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. Endoplasmic reticulum. Note=Resides in the Golgi apparatus membrane and is secreted following propeptide cleavage. Retained in the endoplasmic reticulum (ER) in response to ER stress where it phosphorylates P4HB.
Sequence:
MKMILVRRFRVLILVVFLLACALHIAVDLLPKLDRRATRSSGEPGCSCAQPAAEAAGPGWAQARSRPGESAGGDAGWPNKHTLRILQDFSSDPASNLTSHSLEKLPSAAEPVDHAPRGQEPRSPPPRDPAHRPLLRDPGPRPRVPPPGPSGDGSLLAKLFEHPLYQGAVPPLTEDDVLFNVNSDIRFNPKAAENPDWPHEGAEGAEFLPTGEAAVNLYPNWLKFHIGINRYELYSRHNPAIDALLRDLGSQKITSVAMKSGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDYERHNAEIAAFHLDRILDFRRVPPVAGRMINMTKEIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGRPDQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSGHRILDIMDMTVFDFLMGNMDRHHYETFEKFGNETFIIHLDNGRGFGKYSHDELSILAPLHQCCRIRRSTYLRLQLLAKEEHKLSLLMAESLQHDKVAPVLYQLHLEALDRRLRIVLQAVRDCVEKDGLSSVVEDDLATEHRASTER
The following text describes a protein:
Function:
Catalyzes the 2-beta-hydroxylation of several biologically active gibberellins, leading to the homeostatic regulation of their endogenous level. Catabolism of gibberellins (GAs) plays a central role in plant development. Converts GA9/GA20 to GA51/GA29 and GA4/GA1 to GA34/GA8.
Sequence:
MVVLSLPVLDNGLPHIIKTSKPTSNTFTGIPVVDLSNLANAKTLIVNACKEFGFFKVVNHGVPMNLLTELEAEAVRFFESPQHQKDKSGPPNPFGYGNKKIGPNGDVGWVEYLLFCTNPHNPNAAAVPGLQQTLRNLVNEYVSAVRNMACEVLEMIAEELQLAESDALSKMIRDEKSDSCFRLNHYPPCPDLGELSGRRSLVGFGEHTDPQIMSVLRSNNTSGLQICLKDGAWVSVPSDPESFFLNVGDSLQVMTNGRFRSVKHRVLAADNMKSRVSMIYFGGPPLTERITPLSEIMEEGEESLYKEFTWSEYKKSAYKTKLGDDRLEFFLKSASSA
The following text describes a protein:
Function:
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.
Sequence:
MEASSPLAAIRPAPPSFSQPEVLGPRNGNLAPPTGLFNFKRSNADLFNTKHAGRSSPKGSLVAGSSENFKLNEAGSPLPPTPRRALFTSTGIENAVEGRGYATTPPPPASSSPAVNRLDMSPVPIKAPFLSRLAASPSPAAVDSGDEDTLPDSPAAVRQLSQESKGIGAERRRLGLSRPPLARAKGYSTSSIPGRSNGSGSGLPPFRFGARNLKVPISPSVSLSLSECFEESPPQERRTPVLPGSPCSNAAAARCKTHFGSGSSINSVRKRSPTNNARTPSNPFARQRKTFRRSLSMFESPGDIVKPKERTSLPSSLKSVVDVNEPQEPLLPHFFPSGENDSIPRISRDTLLEVLDGKYGSQYSHRMIIDCRFEYEYEGGHIDGAINYNDKELLARHLFETPMEGRTLLIFHCEYSAHRAPIMARHIRSEDRTINAEFYPKLTYPDVYILDGGYSGFFQNHRERCCPQAYIEMNDAEHVNTCEREMGRLRQTRKGFSRAQTYAFGQRERKSDKFEAVSPTAPGRKVSRDDEEDMIGASPILGNDRSHSRRMATF
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MATALDPDQPKKQKILVEEMAPLKGVQEQQVRHECEVTKPEKEKGEETRIENGKLIVVTDSCGRVESSGKISEPMEAHNEGSNLERHQAKPKEKIEYKCSEREQRFIQHLDLIEHASTHTGKKLCESDVCQSSSLTGHKKVLSREKGHQCHECGKAFQRSSHLVRHQKIHLGEKPYQCNECGKVFSQNAGLLEHLRIHTGEKPYLCIHCGKNFRRSSHLNRHQRIHSQEEPCECKECGKTFSQALLLTHHQRIHSHSKSHQCNECGKAFSLTSDLIRHHRIHTGEKPFKCNICQKAFRLNSHLAQHVRIHNEEKPYQCSECGEAFRQRSGLFQHQRYHHKDKLA
The following text describes a protein:
Function:
Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
Sequence:
MSTEKTITPADILAARRRISGIVQPTPLEVSRPLSALTGAEVWLKLELAQVTGSFKLRGAANALRQLPPATHVVACSAGNHALGVAHTAALTGTPATLVVPTTASPAKVTALRRYPVEVILHGAGYDEAETEALRLAAHHGWHFVSPYNDPAVIAGQGTLAIEVWDALPDVDMVVVAVGGGGLASGVGIWARAMNPRVRIIGVQAAASAAMAAALRAGRVVPAPDEPTLADGLAGGIASDTITLPILQQVLDEMILVEEAAIARAMRWLIDEHHLIVEGSAAVTVAALLEGQITHLVGKRIVALLCGRNVAISTLHHILAVPPKDGASSH
The following text describes a protein:
Function:
Involved in cell wall metabolism and required for the separation of the mother and daughter cells.
Sequence:
MDALVNSFEDLNTSHTTSRYRAKRHHARTKSSPGSIKRNQSIRRHSRTLSTHYDSSNPYQDASTSYAQLSMGRRTEGSSTKPRPKSYVEPSHTQTQAHYATDSHHPSHSRSHSQTGHGPRATFRHHHHRSKSHTNPRSRFELRPQSHHETYTYLPDDPSPQFDEPNFSWMEEAENQLSELQSKYKPEPMAASTSLSWQIPDESHHLTSVAVHESSPLIAVGSGGKENNLFVYETTQDKGLIHHQTISLPAIHGLKWLSPSQQVADLGNILATSHSNGLAHLVLLPDCYSSDPAEILKRFNHKHHVSIKDTLSTRIKHLELTTPAWRSSVSSSLATLYSQHLFLWDPSRGDTPVLTRKVKRAEAFSLSPFQDGQVAAACGKYTSLLDLRAKSGSVNLLAGNTNLCAYSPMNSNLLATAHSDVSGLQENCVRIWDSRHTAGPLHKLEGHTDQIRSLEWSKFNPCELHTSSNDGSLRLWNIGRQQETKARPSLEVYSGDLAAQWDEQKASAQWLPRSARQMQQRGLAFNVAPLNIQKKEKKEKKPALYSSSVIAKTPHAAVASASFMPTGSMHPSVVTVDSYGSLGIHSMPSATPYNTEPETPRTLTARMSVQSFASTDMSSDFTEADMSSASDTSPMTSPSMASAATFQSSYDSPVKACIPEARPATYETSVSSSFIPPLQIKKRVPSGPRPEGSHVRRPSRESRNMLPELDLDFDFGLTA
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MGNTFSFMSNVTGSEKLSSFKIQKTPTYDEISRELSEVLVSSELIDDIFERCCFMTIDFFFDTYKSDDTLKCQHSPTKSEWFFTCSKCCLANNSCICTLCFLSGNHISEGHSFSLFEANQAAVCDCGNSEAIKREGFCSEHINVNEISKKERIDKLPFFIKKDVHIFFRYLFQYLQNLSIKSTAAAATQKNTEKLEIEGDIQTIINWLSEVCKESSTLIHIMAEEFTQRVLEFENDDNNEKVEKEEEKENNSDDDEYYYSKFKLYQHKPLPYKNDNESIQQQWEGHHFLGYIFSKIELLDQFLPLLVLLIDNHSAFKIVLFEEYLKNYISIFSPRDSKSSSITLTIASFYMENKILVPFSTGYSRHNVLELILRSHKTIYVPLLLPFYQADSKVEKEVMLQSDLSAFTKLMKNPLVVKYFSKQEDKFKLLFEFAEQLHRFTSPQFVDPSITTTKFLLLMEHRLLLSIRSMFQTAESIRDQDPEFYQFLTDKVTENLITNMEKIKKRPTFDRCGMQLPHQDFFQKFTYSEIPVHFPLYRMLSTMLLMTKMDPMLLISKYNFQEADIIDMLTTLLLFRVCYVSYDDNNSIENCTDITMVSDLHMIQISISLLGPRKFLYIFFNVLTSIDTNPAAFTDIFSMFIGSLQLRATLTPTKQDIVYNLLQGVFSGIFFKLHFRSFDAVLLDVTEDQINDIYLPEITGKGNQAKELLNNDMWQYFDPYYPLFSINYRNLIKTNAKDRFKKYQTLKKIPESNPLPPIMDPLPLELSGVSEIYNDPTLFEIILCVVADCVFPSTFVGYDDSFEMQPILKMLISKPDTILSEMFYIFVLGIKSFKEFTLPKLTQSEKQLIIETIFDYFNSTTTTTTTTNQEENNDKKDDHNDEKVENQENQENQENQEGKEKESIENVEEKEEDRIRRENNNSRFKFDFTLKTKNNYAIYNLLRIYNVEIDIGVKEKLSFLDILFKFWDLMTNKSQYLELRSSLLYIFNFLLEFDPIFEKVFSDNKIDLVRDVETSAQDELAQKKLMAEKKERLLQQMREQQKSFLENYNKILVEGDEEEEEEDDDDDDNDDGDDTDENHYENEQDNYNKESEENQGKEGNEEDGDKDDKDDDDEEEAAPLKLRNTIKAPDTYENDDEGCNDDKDVENFEKQKEQSTINIEIQSGGIDENEINNEITKEKQNEGEGEEEVEEIEIGEEEGEEVEIKVDVKKSNKNNKHHKHESRKIEISIEEEGEFEPCIICKSGERGGRLFTMGYIDLSSVNHQNSVQNNFNLANDTEMGLDPLYQHFIETFYLTDIKPGTTHYIPYKDDPAGLFACYIFQRSPSTYISSCGHNIHKNCLDKYVKEQEQQKTDEFITAFNCPLCSRPSDFILPLGEPLDSNQYRSDANDMFTKLCYYDFLVLMDPEKKYSIDKYLWKFVLQNIETLELKSRKTNLYSQEDYFIISEIDFQKELTTTTRLFNVITSANVEPDQILPIYDPSSFFMDPFTSSSYSIFLSKKDHLSLIFEGISKYLFNVVLFHCIKKRVVPENQLNNNVQTQKLVENEFQLLFSNNNNNNNNTSMDKDIELEFKNQIHPYIRKVLILYSLISNTTIIDTKDDFPTVPSSSTPLTVELLSDFDKCIGYFGYSNVQSMFNHLLNKDTFELTLSKFMKKKKITSTISTTPTLYCSYPPPSDYRSLPRFISLPEKFVTLMQENICAGNCDCDSLLKLVCLLCGQSVCTVNACKKGGAVSHCYVCSSTPLGFFHLIDKPLIQVYHFQFGSFKNSFYTHIYLDKDGQKSSTTSVEISLSQKRLKKLYKYWMDTTNSRKFLITK
The following text describes a protein:
Function:
Regulates plant architecture, shape of epidermal pavement cells and branching of trichomes.
Sequence:
MVSRSYSNLLELASGDSPTFGRMNRQIPRIMAVAGIMSNIDNDSKDTDLSPKDRIIIVANELPIRAQRRVDGNGSGSSSSSTCCSKGWNFSWDENSLLLQLKDGLGDEAIEVIYVGCLKEEIPLNEQEEVYQILLESFKCVPTFLPLDLYTRYYHGFCKQQLWPLFHYMLPLSPDLGGRFDRTLWQAYVSVNKIFADRIMEVINPEDDFVWIHDYHLMVLPTFLRKRFNRVKLGFFLHSPFPSSEIYKTLPIREELLRALLNSDLIGFHTFDYARHFLSCCSRMLGLTYESKRGYIGLEYYGRTVSIKILPVGIHMGQLQSVLSLPETERKVGELIERYGRKGRTMLLGVDDMDIFKGITLKLLAMEQLLMQHPEWQGKVVLVQIANPARGKGKDVKEMQAETYSTVKRINETFGRPGYDPIVLIDAPLKFYERVAYYVVAECCLVTAVRDGMNLIPYEYIVSRQGNEKLDKILKLEANNRNKKSMLVVSEFIGCSPSLSGAIRVNPWNVDAVADAMDSALEVAEPEKQLRHEKHYKYVSTHDVGYWARSFLQDLERSCGEHGRRRCWGIGFGLSFRVVALDQSFRKLSMEHIVSAYKRTKTRAILLDYDDTLMPQGSIDKRPSSKSIDILNTLCRDKGNLVFIVSAKSRETLSDWFSPCEKLGIAAEHGYFLRLRKAVEWENCVAAVDCSWKQIAEPVMELYTETTDGSTIEDKETALVWSYEDADPDFGSCQAKELLDHLESVLANEPVTVKRGQNYVEVKPQGVSKGLIARRMLSMMQERGTLPEFVLCIGDDRSDEDMFEVICSSTEGPSIAPRAEIFACTVGQKPSKAKYYLDDTTEIVRLMHGLASVTDQITPV
The following text describes a protein:
Function:
Supplies CDP-diacylglycerol, which may play an important role as both a precursor to phosphoinositide biosynthesis in the plasma membrane and as a negative effector of phosphatidylinositol 4-kinase activity, thereby exerting an effect on cell proliferation via a lipid-dependent signal transduction cascade.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle. Note=Exclusively present in the ER, and not in mitochondria. Also associated with post-Golgi apparatus secretory vesicles destined for the plasma membrane.
Sequence:
MSDNPEMKPHGTSKEIVESVTDATSKAIDKLQEELHKDASESVTPVTKESTAATKESRKYNFFIRTVWTFVMISGFFITLASGHAWCIVLILGCQIATFKECIAVTSASGREKNLPLTKTLNWYLLFTTIYYLDGKSLFKFFQATFYEYPVLNFIVTNHKFICYCLYLMGFVLFVCSLRKGFLKFQFGSLCVTHMVLLLVVFQAHLIIKNVLNGLFWFLLPCGLVIVNDIFAYLCGITFGKTKLIEISPKKTLEGFLGAWFFTALASIILTRILSPYTYLTCPVEDLHTNFFSNLTCELNPVFLPQVYRLPPIFFDKVQINSITVKPIYFHALNLATFASLFAPFGGFFASGLKRTFKVKDFGHSIPGHGGITDRVDCQFIMGSFANLYYETFISEHRITVDTVLSTILMNLNDKQIIELIDILIRFLSKKGIISAKNFEKLADIFNVTKKSLTNHS
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Subcellular Localization:
Cytoplasm.
Sequence:
MANTVILVDQPTLEKMKQTYLPFSNPKLPPGAVFAAKKPGVSITGYKSRKVMFQGVNGEAEAKKWVATLPESKAKAPSVSKGILPANFASKNVIGSDEVGTGDFFGPITVCAAYVDAEMMPLLKELGVKDSKAMKDPEICRIAEKIMPLVPHSVLLCPNPKYNELQKRGMNQGQMKALLHNRAIENVLKKLAPIKPEAILIDQFAEKNTYYRYLAKEPSIIREDVFFATKAEGLHLSVAAASIIARYKFVQAFDAMSKEVGIPLPKGAGPHVDAVAAEIIERFGLETLAKYTKQHFANTEKALKMVKK
The following text describes a protein:
Function:
Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through targeting of proteins to the cilia. Plays a role in organogenesis and is involved in the regulation of the Hippo signaling pathway.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium axoneme. Note=Predominantly cytoplasmic. Localizes to the proximal region of the primary cilium and is not observed in dividing cells.
Sequence:
MEKYERIRVVGRGAFGIVHLCLRKADQKLVILKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNIHTDVGSVRMRRAEKSLTPGPPIASGSTGSRATSARCRGVPRGPVRPAIPPPLSSVYAWGGGLSSPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGTLLPGAVELPQPQFVSRFLEGQSGVTIKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGNLTDISQPTIVEALLGYEMVQVACGASHVLALSTDGELFAWGRGDGGRLGLGTRESHNCPQQVPVAPGQEAQRVVCGIDSSMILTSPGRVLACGSNRFNKLGLDHLSLDEEPVPYQQVEEALSFTPLGSAPLDQEPLLCVDLGTAHSAAITASGDCYTFGSNQHGQLGTSSRRVSRAPCRVQGLEGIKMVMVACGDAFTVAVGAEGEVYSWGKGTRGRLGRRDEDAGLPRPVQLDETHPYMVTSVSCCHGNTLLAVRSVTDEPVPP
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP85 is involved in nuclear poly(A)+ RNA and pre-ribosome export, in GSP1 nuclear import, in NPC assembly and distribution, as well as in nuclear envelope organization.
Miscellaneous:
MISCELLANEOUS: Present with 7920 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Sequence:
MTIDDSNRLLMDVDQFDFLDDGTAQLSNNKTDEEEQLYKRDPVSGAILVPMTVNDQPIEKNGDKMPLKFKLGPLSYQNMAFITAKDKYKLYPVRIPRLDTSKEFSAYVSGLFEIYRDLGDDRVFNVPTIGVVNSNFAKEHNATVNLAMEAILNELEVFIGRVKDQDGRVNRFYELEESLTVLNCLRTMYFILDGQDVEENRSEFIESLLNWINRSDGEPDEEYIEQVFSVKDSTAGKKVFETQYFWKLLNQLVLRGLLSQAIGCIERSDLLPYLSDTCAVSFDAVSDSIELLKQYPKDSSSTFREWKNLVLKLSQAFGSSATDISGELRDYIEDFLLVIGGNQRKILQYSRTWYESFCGFLLYYIPSLELSAEYLQMSLEANVVDITNDWEQPCVDIISGKIHSILPVMESLDSCTAAFTAMICEAKGLIENIFEGEKNSDDYSNEDNEMLEDLFSYRNGMASYMLNSFAFELCSLGDKELWPVAIGLIALSATGTRSAKKMVIAELLPHYPFVTNDDIEWMLSICVEWRLPEIAKEIYTTLGNQMLSAHNIIESIANFSRAGKYELVKSYSWLLFEASCMEGQKLDDPVLNAIVSKNSPAEDDVIIPQDILDCVVTNSMRQTLAPYAVLSQFYELRDREDWGQALRLLLLLIEFPYLPKHYLVLLVAKFLYPIFLLDDKKLMDEDSVATVIEVIETKWDDADEKSSNLYETIIEADKSLPSSMATLLKNLRKKLNFKLCQAFM