lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MSSSRSWSRSLLLTCISLCLLSIARCESLLDDVVKRSNDSLLWGAYRPNLYVGVRPRIPKSLMAGLMWTNVDTYGSISRIRHACEQSEDMGYYGWDSYDARLGGHQVIDDYGMGIKLDVDFVKLPEAENGQNWALRVRGTPKKGAPEDIKTAMFFYTYLEGEGILEIQKNEENEGSRPYIVGETPDLGTFLIATKNRFGEHPTFLTAPNNFEDAEETVMDSDYYISLNVEEDDIWKMKDVLLQLLDQKIRIDLQAKGITSLEDLPPAFEELVLPNVAGNTNVQIVEKVFEGAFEFDIIYNSVPFLNVVTEDVITAQIESNKAAFKERFEQTFPIAAPFKNESSLQLFSQRAFANLYGGIGYFYGNSIVSTHGVEDAEDGDYEFAHGFENADMKLQEGTAKLDVERTLFTATPSRPHFARGFYWDEGFHLIPLGLWDTDLSLEILQSWFSLIDEKGWLGREQILGPEARSQVPAEFQTQYPDIANPPTLILALKAFIEQMKSYSGAGDFAERALNQEGDGVSGVTSEADLLRVSHLEFPELTTKFLRSLYPKLRKHYYWFRDTQAGDLESWERDAFSDVEGYRWRGRTYEHCLASGLDDYPRAQPPSFAELHVDLMSWMISFTKNLRFVAEFLGEEEDAATFAEYENNMMHNLDDLHWDEDTGMYCDASVDEYDDPLFVCHTGYVSLMPLMLGLLPSDSPKLGRLLEVLRDEDELWSPYGIRSLSRSDRFYGQGENYWRGPIWINMNYMVLSSLYKNYMQVSGPYQELATAIYNELRVNVVNTVYREWARSGIFYEQYNSETGVGQRTKGFTGWTSLVVNILSEQY
The following text describes a protein:
Function:
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivate expression in an agonist- and AF2-dependent manner. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway (By similarity).
Subcellular Localization:
Nucleus.
Domain:
Contains one Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which is essential for the association with nuclear receptors.
Sequence:
EQIMTNQMQGNKAQFNSQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVSNSPSQVMGIQGQVLRPPGPSPHMAQQHTDPATTANNDVNLSQMMPDVSMQQTSMVPPHVQSMQGNSASGSHFSGHGVSFNAPFGGAPNGTQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKQKKKKPPRKKKNCHQDLNTPDSRPAGLEEVDQQSLPGEQGINLDNTGPKLPDFSNRPPGYPTQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQPQPQPPPPSQPQSQQQQQQQQQQQQQQMMMMLMMQQDPKSIRLPVSQNVHPPRGPLNPDSQRVPMQQSGNVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNSSS
The following text describes a protein:
Function:
Involved in chloroplast mRNA stability. Binds specifically to two intergenic RNA regions of similar sequence located in the chloroplast atpH 5'-UTR and psaJ 3'-UTR, and serves as a barrier to RNA decay. Binding to a specific site in the intergenic region of the chloroplast atpH is sufficient to block 5'-3' and 3'-5' exonucleases. Acts as a protein barrier to block mRNA degradation by exonucleases, and defines processed mRNA termini in chloroplasts. Remodels the structure of the atpH ribosome-binding site in a manner that can account for its ability to enhance translation. Stabilizes a RNA 3'-end downstream from psaI. Binds atpH RNA as a monomer.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MEATGRGLFPNKPTLPAGPRKRGPLLPAAPPPPSPSSLPLDSLLLHLTAPAPAPAPAPRRSHQTPTPPHSFLSPDAQVLVLAISSHPLPTLAAFLASRRDELLRADITSLLKALELSGHWEWALALLRWAGKEGAADASALEMVVRALGREGQHDAVCALLDETPLPPGSRLDVRAYTTVLHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLDVYGRMGRSWPRIVALLDEMRAAGVEPDGFTASTVIAACCRDGLVDEAVAFFEDLKARGHAPCVVTYNALLQVFGKAGNYTEALRVLGEMEQNGCQPDAVTYNELAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTGFVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNRVTWNTMLAVCGKRGMEDYVTRVLEGMRSCGVELSRDTYNTLIAAYGRCGSRTNAFKMYNEMTSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKMRTKGFKPNEQSYSLLLQCYAKGGNVAGIAAIENEVYGSGAVFPSWVILRTLVIANFKCRRLDGMETAFQEVKARGYNPDLVIFNSMLSIYAKNGMYSKATEVFDSIKRSGLSPDLITYNSLMDMYAKCSESWEAEKILNQLKCSQTMKPDVVSYNTVINGFCKQGLVKEAQRVLSEMVADGMAPCAVTYHTLVGGYSSLEMFSEAREVIGYMVQHGLKPMELTYRRVVESYCRAKRFEEARGFLSEVSETDLDFDKKALEAYIEDAQFGR
The following text describes a protein:
Function:
Essential for recycling GMP and indirectly, cGMP.
Subcellular Localization:
Cytoplasm.
Sequence:
MHNDFNLLILSGPSGAGKSTLTKYLQEKIPKTHFSLSTTTRKPREGEVDGLHYNFVSEEEFKQGIEKGQFLEWAIVHNHYYGTSKIPVEKALKEGKIVIFDIDVQGHEILKKHYPNACSVFISTKNQEILKERLLLRGTDSKETIEKRLINAYKEMQCLESFDYLIINEDLEKSKEIILSIAKTLVHRLKAFNFEKICKAWKNETL
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system.
Sequence:
MAVGLIRRGDIFLTHFGPARAGEPDFKRPAVVITNNVANAKADAVTVIPLTSNLETLYDFQLLLPTERTGLNLDSKAQTELISCIAISRIGKHLGQVPADLMAELDARIRLHLAL
The following text describes a protein:
Function:
Non-catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. The TSC-TBC complex acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. In absence of nutrients, the TSC-TBC complex inhibits mTORC1, thereby preventing phosphorylation of ribosomal protein S6 kinase (RPS6KB1 and RPS6KB2) and EIF4EBP1 (4E-BP1) by the mTORC1 signaling. The TSC-TBC complex is inactivated in response to nutrients, relieving inhibition of mTORC1.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasmic vesicle. Lysosome membrane.
Sequence:
MADERNFRSTYYEKVGCRGVEERKSLEILLKEKPLNLTKLTQFCIRFTVPKIHRTVLWNSLLGVTPVYDKSREYVMEQRVAVYNDLLKALKIMRIVDENTPTSRVLYAMWLLEKKQLYLGRDITQESHFCNITKVLLEIFDNDIETYWMAKSLYDYSEEVSLEMGKLSDLTYTILEKEDSGLYIHLKSCDMLTALPLADWYRSFFAGVLSEPALIRIWDKICGGAIKIVVFVMIEILRMLRRRVLRCVDQKSLFECIDSIKNEQETADMIVNGAIELWQQNKGHEYIPQSKVKALS
The following text describes a protein:
Function:
May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MGSASPGLSNVSPGCLLLFPDVAPRTGTEKAASGAMGPEKQEWSPSPPATPEQGLSAFYLSYFNMYPDDSSWVAKVPEARAGEDHPEEPEQCPVIDSQASGSTLDEHSLEQVQSMVVGEVLKDIETACKLLNITADPGDWSPGNVQKWLLWTEHQYRLPPAGKAFQELGGKELCAMSEEQFRQRAPLGGDVLHAHLDIWKSAAWMKERTSPGTLHYCASTSEEGWTDGEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGVRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPV
The following text describes a protein:
Function:
Catalyzes the stereoinversion of LL-2,6-diaminopimelate (L,L-DAP) to meso-diaminopimelate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
Subcellular Localization:
Cytoplasm.
Sequence:
MGFSSLLTTCRYLLYSGAGNSFILGESMPSLEDVLFLCQEEMVDGFLCVESSEIADAKLTVFNSDGSIASMCGNGLRCAMAHVAQCFGLEDVSIETERGVYQGKFFSMNRVLVDMTLPDWKKAERKLTHVLPGMPEQVFFIDTGVPHVVVFVSDLSKVPVQEWGSFLRYHEDFAPEGVNVDFVQRKKDDLLLVYTYERGCERETLSCGTGMLASALVAADIFSLGQDFSIAVCSRSRNLIKIFSEKGKVFLEGPVSLLNRSENFGWLEPKSRRFG
The following text describes a protein:
Function:
Involved in chromosome segregation during meiosis. Involved in meiotic telomere clustering (bouquet formation) and telomere-led rapid prophase movements.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Sequence:
MMDGSITRKVTSTLSNQLATWKWKLQLSLLERKLATINNDYFLLQWELLFITNEVMKWKEMIAFLESQLFCTTQNFVAQETHDRETFQSLVDDYNKQLSENNLIISVLKSRPQLSSFPIYLSDEVCSHLKFVIAELNSLIIVFFISLVFLWVSIEV
The following text describes a protein:
Function:
Glycosyltransferase with a proposed role in glycosphingolipid biosynthesis. Involved in susceptibility to pore-forming crystal toxins in conjunction with bre-1, bre-2, bre-4 and bre-5. Involved in resistance to the nematotoxic C.cinerea galectin Cgl2. Has a role in determining brood size.
Subcellular Localization:
Cytoplasm. Note=In punctate structures throughout the cell.
Sequence:
MNCEVKHALHCAVLVAWIVCFAYFCGVFTEPVEGSVPESPVASYGLIWTVCLYLLRFTALLVLPQCLCNLGGLMMFNAFREKVQLKAAPLLSPFVCFRVVTKGNFPLLVKENIDTNMKTCFEAGMENFIFEVVTDKAINLPPNPRVREVVVPTVYKTKSGAKFKARALQYCLEDDVNILQPTDWIVHLDEETLLTTNAICGILNFCEDGKHQFGQGVITYANGDIVNWLTTLSDSFRVADDMGKLRFQFKLFHKPLFGWKGSYVVTQVEAERDVSYDHGMEGSIAEDCFFSMVAMKHGYSFDFIEGEMHEKSPFTMWDFLQQRKRWLQGILLTVHSSKIAVVHKALLALSLYAWATMPLTSLQVFLCPLFPLPRCLPFDFLLSFVGALNLYMYIFGVVKSFSHKYRNSLLRLAMYLAGALMTIPFNILIENAAVLVGMFGRKDQFYIVNKDIQTV
The following text describes a protein:
Function:
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Domain:
Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
Sequence:
MASATLRRSLLLAACLACGFAFAVAQEAPRAHPLTNLPPAGEISTGFFFPEFPTKQFIAGQPVKVVVGIRNEAAEKYNISAVMGSLNNAQDFRAYYWNFTQQVYFQVVEPSKELSVEYTFLPPKDLPPNDYQVALTVFYEAADGFKSSTFFNQTVSVSEKPQLIDWKLIFLYVIFIGLVAAGGYYVWTTIKDVPLVKSMVGKKKSVKTDESRTFNNDEWVAGTHVANFYNKKTAPAKAGAKKAQ
The following text describes a protein:
Function:
Involved in nucleotide excision repair (NER) of damaged ribosomal DNA (rDNA). Required for the repair of the RNA polymerase I-transcribed strand of rDNA.
Miscellaneous:
MISCELLANEOUS: Present with 78 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MAKRLLESSQNDQANRKNSKIEKKEVSFYEEEETDDSFDSFYQDEEDDLSDIDWEEVSLDGSLTVTFGNIRRDREKVSKYKRKHNKKAFNYQRLKYGLHLIMIPFMLFLLKSRMKWIDDERLNRRLRRSVPKLIGKKFKDWDVRDPAFKMDSLRTLLLGLVLWFRSNYKMNSNGIRQNFNRLQYLIKYADNQNENSISESTYKKVLENQQEFYGNRPLINHGVEDIRKMAKRKMANRDILTLFFFIILENVLPGPKKLYLCFALPLHDYDIRCNKVKWQIEHGIGKVPNRFDSDLIQPYFWIELEVPTLSDGELYIIDPIAHLGEREMVLKTREDQFVPTYQPSVDMKYNLNQKFHYVVRINHAEKVLQDVSPRYVPNVCYRYFELSESSPILKSKHYTSYQYLSKWLKVLNKKKASVHHYAIMKKIALTNFTLPKSVTEIKRTDNFVIPSLLKSNEVLKACAKQAATFTKGDNSQEPIFWRRDVIQLKSKQHWAILGRSILPNAQPLKRKKYLPMRERMVRNLDKYVIKELFSYEQTMKSPKYPSTYCDHLGQEHVITDLSHYKNKFGNIEIYSKETKPDGFELIPLSKEVDIKCLIKEYNKGKRKMQKIKYLDVVSGFDFKQKKGHAIPKIESILVKETDYKAVQLLKQQTKVLLGLSFWDILLRKLRVNDRLNAEYGNVGNNEETLDDH
The following text describes a protein:
Function:
May be involved in neurite outgrowth.
Sequence:
MGSLKNETKGLMEEHQLCEKTDDGERQVNSKQNSAGDGRSCQEDNQPELFQNTNSEEDTVKNAISKEVLSEEKGDKDEMPWAQQPAADEATATKNNITISKIRPSDGEAQDTDAVFECESDAATDSISLPVPLTPDPSDPRSPAPFGQNHIRTQVSLEVVQCRSAATSPMTPPQGESSFFFPSTFGKSDAGGDTTDTGLQVGQQVEFCSVATSPMTPKTPYATAFPALVGKETVQMKEKEKNGQEQSNNSQQVVSIVTSQEEVESQKTNAVKMVAKESDPVSSGSPGNASTFLTAGSRDSKGTVENSNQQNKQQRMGSMDQDITILVTHHGNNEDEDEEQADSYVVESETIKVDECEEGRANKNDEKSTDEKTHDTSDPEQKQKQAKEEGKPCMRAESLEVTERKDACEETADASPIKSPIPESPAPFGCHNIRTQVSLEVVQCQSAATSPMTPPEGDQAFCFPSTFGKFAAVCTETKDAELQVGQEVEFRSVATAPMTPRTPIATTFPDIKRGVSIEEKITEEEEKKEPVTEDEKEEQVNKDEKAEDKEETINCNNTDDEKCEEPVQEVSWDEKGMTWEVYGAVVEVAVLGSAIQKHLEKQVKKQKRQTSLPPPPPLNPSATPLTTELVQGGSGKGCGGKRREDRKVNRRRRNPFRQLMENMQQPHCCSRAHTTE
The following text describes a protein:
Function:
Involved in ER-associated protein degradation (ERAD).
Miscellaneous:
MISCELLANEOUS: Present with 1270 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MAIKPTKSFQNCLEAEVPGYNDCPTVLFSIDPNSGPRSKSKQRTKSKRCVSGRLATEVLDLYGNTKTATTPPPVLRRPSVTAAQQESACEGVLVKDQGDRQLQPILCSKEELVAKINDLCVCGSKLSSKELEFYKKKLDSNITKILQNEHTKTVLSQIFNEKDKNMAVKTIKHWMVTDTTISNWCPAFLKIFENAMPN
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
Miscellaneous:
MISCELLANEOUS: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
Domain:
Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.
Sequence:
MDLLAPLAAVILTYREVDADTLGRVGEEMKKCIEILGVKRPMFVLHTCGRVEAYLYNASEEEINSVTLRYRRYAESIRVVRGVEAARHLFRVAAGLESMLIGETDILGQVEEAFDRQVKAGFTKGLLKTIVERAIRAGKRVRAETGISRGPAGLGSLSIIYVSQLLDLTKSKVAVLGAGAVGAGLAKELAERGVAKLYILNRTLEKAVEIANKLGAEARPLTREEVQKCLMECDVVFSSVHSLEYVIDRVPDGAVVKIIVDLGVPQTVAPGLPVRVVRLSDLKQLAEKYSEARKQEAARAEAIVEEELAKLPQILARRYIEEAVSHLLEKAMEVAEEEGKRAGCPTAVLAARTTVKRTLFPIIEVLKKMAEDGRLEDAVKVVEILRSQKPLLRQSEE
The following text describes a protein:
Function:
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
Sequence:
MYFNSVGVPECPNWTGFSLIMPAVSVGNIGQLTCDLLINTLKLTKMGCFSDQSLQPLCGNDAFHSTGIAAGKLVTSAEVFESQEKKIVVIQQRAALVQGRAGEFRRKLIEWIKEKGFSRVILITSCFAYEKTDAIIQSNTCRYLMTPSLEAKKDEFVSNLLKYPQLEKKPAEEGLELPRQPDDIPEAARDIRLSGGGIAKKLFIDCCKEDVPMAVLLLFCAEGDNTPHAMMMASFTNALLHLIPEPTKLPAGTPPWKAMWRPPASWTMLFGGPVDPTIY
The following text describes a protein:
Function:
Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of excision-repair.
Subcellular Localization:
Nucleus.
Sequence:
MGVNGLWTVLQPCARPTNLSTLNRKRLAIDASIWIYQFLKAVRDKEGNALRNSHVVGFFRRICKLLWYGIKPVFVFDGGAPALKRATIQARRRRREGRRDDATRTAGKLLAVQMHRMAEEEDERRRKRAEAREGNKTAAAAAAAEEEEQEVLPDMDKVVYADELGMSKQERQKSRRFHKQDAYHLPDLDGGIEAMGKPDDPRIMSVEELEEYARQFENGEDINLYDFSKIDFDGEFFKSLPPADRYNILNAARLRSRLRMGLSKEQLDVMFPNRMDFSRFQIERVKERNHLTQRLMYEMGMTGLDLTLAVNATRVAGDQNREYILVKNEGAEGGYALGVVSTEKDKGQMTNPIDVDELEFQFQGKGEEEEDSEEDVEFEDVPIEGLNRLPKLTRAAGYRPRGTANSRRQFYEPRQSEEAEDEDEDDEALFVDNGQDAVYGEENAVEADEEEDLNKAIAMSLQNQHGVGLSEEKEDEDMEFEEVTPPEWTQKAVEAPKPIVSTSGRMVAHIVNNRASAAVPRRRESTDSSDSEGDIRAAMAAARRKQAKAPAPKPVVENRPAPTNTPFKGPLPFEKLNWKQLLGGNRPKAKSQKEKVSEPPKPVETGEMEPQSDDDAGGFEKEPKDAPRPLPPWLANNDEDIRDTVRKQREQDRQMAEEDENLAREEQARIRKQREDEVMMIESSDESDGDLEILDAPPSPKKLTQMPGPSLPSLDDEVSQEPVETSRQSPSPNEEEGDDIVFEDVTLPSQTMTLSFGPPATQAEEDAQIEADLFKDVLPPPAQQERVEGLAAVPDDTTTDIVPDPDAPALSEFEDDFSDPEEQELLASLAQEAEEHARFATQLNHKTFQENQAAYEQELKALRTQQRKDRRDADEVTQIMITECQALLRFFGIPYITAPMEAEAQCAELVRLGLVDGIVTDDSDTFLFGGTRVYKNMFNGNKFVECYLSSDIERDLSLSRDQLIALAQLLGSDYTEGLSGVGPVTAVEILSEFPPEPTPISSLTTFKEWWTKIQSSPQPDPSLLSTPFRRKFRKAQATKLFLPVGFPNPAVFDAYLHPEVDSTPEPFQWGVPDLEGLRQFLMQTIGWSQERTDEVLVPVIRDMNKREREGTQSNITRFFEGGVGSGTVRNLGGGGNEEAFAPRRNEVKGSKRMAEAVGRLKARNSKGNSGGGGLSLALPVMAMGPLNGEEEGGNKKRKRGKGKGKGKGKGKKAAAVEEEEEQEDVDGEKEDDAQEGDGDEDDHVVGASLKGKRGAARGRGRGRGKRARA
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MAGAQGDPQKWGMPGWRIEQRYSNKTLIGNWCEETKLFQRGQHSNSSTHRTDFKLYVDHKPDTIIRRSALMRNEGLRKQHLFTHHGNTYSNNMISWYDEQFNKRDREEGDKLPDLRKWDGHKLAWAPERSDYPMQGVPTNFGLHNKMSRRWTSELKAERQGHYITDYRKAYTQHPHTAFPHRFASAPKYLSSHFNPITKINKDLWLRRTPFNMAPEYPPQVTPPSAV
The following text describes a protein:
Function:
Multidomain scaffolding Mg(2+)-independent protein kinase that catalyzes the phosphotransfer from ATP to proteins such as NRXN1, and plays a role in synaptic transmembrane protein anchoring and ion channel trafficking (By similarity). Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking.ontributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein.
Domain:
The first L27 domain binds DLG1 and the second L27 domain probably binds LIN7; The protein kinase domain mediates the interaction with FCHSD2.
Sequence:
MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHHVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPERFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFPPFVVFIAAPTITPGLNEDESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.
Subcellular Localization:
Nucleus.
Sequence:
MNQNTTEPVAATETLAEVPEHVLRGLPEEVRLFPSAVDKTRIGVWATKPILKGKKFGPFVGDKKKRSQVKNNVYMWEVYYPNLGWMCIDATDPEKGNWLRYVNWACSGEEQNLFPLEINRAIYYKTLKPIAPGEELLVWYNGEDNPEIAAAIEEERASARSKRSSPKSRKGKKKSQENKNKGNKIQDIQLKISEPDFTSANMRDSAEGPKEDEEKPSASALEQPATLQEVASQEVPPELATPAPAWEPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEEEEEDDDELEDEGEEAASMPNENSVKEPEIRCDEKPEDLLEEPKTTSEETLEDSSEVTPAMQIPRTKEEANGDVFETFMFPCQHCERKFTTKQGLERHMHIHISTVNHAFKCKYCGKAFGTQINRRRHERRHEAGLKRKPSQTLQPSEDLADGKASGENVASKDDSSPPNLGPDCLIMNSEKASQDTINSSVVEENGEVKELHPCKYCKKVFGTHTNMRRHQRRVHERHLIPKGVRRKGGLEEPQPPAEQAQATQNVYVPSTEPEEEGEADDVYIMDISSNISENLNYYIDGKIQTNNNTSNCDVIEMESASADLYGINCLLTPVTVEITQNIKTTQVPVTEDLPKEPSGSTNSEAKKRRTASPPALPKIKAETDSDPMVPSCSLSLPLSISTTEAVSFHKEKSVYLSSKLKQLLQTQDKLTPPAGISAAEIAKLGPVCVSAPASMLPVTSSRFKRRTSSPPSSPQHSPALRDFGKPSDGKAAWTDAGLTSKKSKLESHSDSPAWSLSGRDERETVSPPCFDEYKMSKEWTASSAFSSVCNQQPLDLSSGVKQKAEGTGKTPVQWESVLDLSVHKKHCSDSEGKEFKESHSVQPTCSAVKKRKPTTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQDVVVQETFNKNFVCNVCESPFLSIKDLTKHLSIHAEEWPFKCEFCVQLFKDKTDLSEHRFLLHGVGNIFVCSVCKKEFAFLCNLQQHQRDLHPDKVCTHHEFESGTLRPQNFTDPSKAHVEHMQSLPEDPLETSKEEEELNDSSEELYTTIKIMASGIKTKDPDVRLGLNQHYPSFKPPPFQYHHRNPMGIGVTATNFTTHNIPQTFTTAIRCTKCGKGVDNMPELHKHILACASASDKKRYTPKKNPVPLKQTVQPKNGVVVLDNSGKNAFRRMGQPKRLNFSVELSKMSSNKLKLNALKKKNQLVQKAILQKNKSAKQKADLKNACESSSHICPYCNREFTYIGSLNKHAAFSCPKKPLSPPKKKVSHSSKKGGHSSPASSDKNSNSNHRRRTADAEIKMQSMQTPLGKTRARSSGPTQVPLPSSSFRSKQNVKFAASVKSKKPSSSSLRNSSPIRMAKITHVEGKKPKAVAKNHSAQLSSKTSRSLHVRVQKSKAVLQSKSTLASKKRTDRFNIKSRERSGGPVTRSLQLAAAADLSENKREDGSAKQELKDFSYSLRLASRCSPPAAPYITRQYRKVKAPAAAQFQGPFFKE
The following text describes a protein:
Function:
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subcellular Localization:
Mitochondrion.
Sequence:
MSARIGRLRGLCLRHVSSTRQTSPIQRRSLNQFISRVQQHDQPALEQRQFRLAVKDNIATVSPNSEEETPLTTTCGSNFLANYRSPFEATIVSQLRSRGALLVGKTNLDEFGMGSHSVHTAFGAVAQEGEHEQQAVKHSAGGSSGGSAVAVATGEADIALGTDTGGSVRLPAGYTGVVGFKPSYGMLSRYGVVPYANSLDTVGLLAKEVRPIAELILGGADKVTRGLWAEHDPLDPTSLSHGARRRCASQRDCYTGPLPKDPYPLKNLKFGLPLEYNITELSPSIRHSWSAAAAKLQSLGARLVPVSLPSTRHALSAYYVIAPAEASSNLAKYDGIRYGTRFTSPTESDAAISEGPEGREEEEEGILYARARTAGFGDEVKRRILLGAYTLSSAAMDNYFLKAQKVRRLVRRDFNRVFALPNPLLDKPERFELSELPETVGLEDKWGPTEVDFLLCPTAPTTAPRLDEVLSEEEKDPVSAYMNDVFTVPASLAGLPAISVPMRVEDKEGAGMAGLQLIGQYWDDARLLAVAETVADVVREEL
The following text describes a protein:
Function:
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Essential for the beta oxidation of unsaturated fatty acids.
Subcellular Localization:
Peroxisome.
Sequence:
MCSLEKRDRLFILKLTGDGEHRLNPTLLDSLRSTINQIRSDPSFSQSVLITTSDGKFFSNGYDLALAESNPSLSVVMDAKLRSLVADLISLPMPTIAAVTGHASAAGCILAMSHDYVLMRRDRGFLYMSELDIELIVPAWFMAVIRGKIGSPAARRDVMLTAAKVTADVGVKMGIVDSAYGSAAETVEAAIKLGEEIVQRGGDGHVYGKMRESLLREVLIHTIGEYESGSSVVRSTGSKL
The following text describes a protein:
Function:
Catalyzes the NADH-dependent reduction of hydroxypyruvate into glycerate in the photorespiratory core cycle. Mediates fatty acid beta-oxidation in germinating seeds when malate dehydrogenase is absent.
Subcellular Localization:
Peroxisome.
Sequence:
MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASPPNASPSIVNSKALGLPVSKL
The following text describes a protein:
Function:
Specifically methylates the N7 position of a guanine in 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MQDPEQFSIESILQRLKERFPTEADEISSFFDWDLVHKFTVFLKEKNEAGGFFSKRDSEEILDRHVLESIYHVYRITKKIGSWKGTQLGDAGTGPGIPGFFFRCLKEHPIVVLIDSQKRKLSHTENFVRSNQIDGVKFQFIRAEESKLSLNYVTSRGFIPYPYSIEAICNLLKINGTYVPFLGKHDMDTNLEKKVLSYSGFKLEFSEDLVPLEFLGMRHIKFLKKVSSPRHGYPRAWKEISKESKGANGKDRID
The following text describes a protein:
Function:
Metalloprotease.
Subcellular Localization:
Cytoplasm. Lipid droplet. Note=Found in ring-like structures resembling invadopodia. In migrating cells it relocalizes from internal structures to the leading edge of cells.
Sequence:
MAAEWGGGVGYSGSGPGRSRWRWSGSVWVRSVLLLLGGLRASATSTPVSLGSSPPCRHHVPSDTEVINKVHLKANHVVKRDVDEHLRIKTVYDKSVEELLPEKKNLVKNKLFPQAISYLEKTFQVRRPAGTILLSRQCATNQYLRKENDPHRYCTGECAAHTKCGPVIVPEEHLQQCRVYRGGKWPHGAVGVPDQEGISDADFVLYVGALATERCSHENIISYAAYCQQEANMDRPIAGYANLCPNMISTQPQEFVGMLSTVKHEVIHALGFSAGLFAFYHDKDGNPLTSRFADGLPPFNYSLGLYQWSDKVVRKVERLWDVRDNKIVRHTVYLLVTPRVVEEARKHFDCPVLEGMELENQGGVGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTGRQMLSPYCDTLRSNPLQLTCRQDQRAVAVCNLQKFPKPLPQEYQYFDELSGIPAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPEIFKNYGAEKYGPHSVCLIQKSAFVMEKCERKLSYPDWGSGCYQVSCSPQGLKVWVQDTSYLCSRAGQVLPVSIQMNGWIHDGNLLCPSCWDFCELCPPETDPPATNLTRALPLDLCSCSSSLVVTLWLLLGNLFPLLAGFLLCIWH
The following text describes a protein:
Function:
This promotes the activity of RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MSLVTDSPVHSSSSDDFAALLDAELEVGSSGSSPDEEDVEADGDNNNDNNDDHDDDDDLDSQRNKRCKTEKLEDLEESRGSTSQGLIEDKIVIHAELSLKKDICTHPGSFGQMCILCGQRLDDESGVTFGYIHKGLRLGNDEIVRLRSTDMKNLLRHKKLYLVLDLDHTLLNSTQLMHLTPDEEYLKGQSDSLQDVSRGSLFMLDFMHMMTKLRPFVRTFLKEASEMFEMYIYTMGDRPYALEMAKLLDPRREYFSDRVISRDDGTQKHQKGLDVVLGQESAVVILDDTENAWMKHKDNLILMERYHYFASSCHQFGYKCKSLSQLKSDESEPDGALASVLKALRQIHHMFFDELDCNLASRDVRQVLKTVQEEVLKGCKIVFSHVFPTNFPAESHPLWKMAEQLGATCSTETDLSVTHVVSTDAGTEKSRWAVKEKKFLVHPRWIEATNYLWQKQPEENFPVSQGKNQ