lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MITNIFRIAGLHQVSWFQLIPDVERSSPSTSRMEKNRQDAMNMLVMMAHVRLQGEGHLSAWTVSPIKEGSITRPTNSDERLKLWIFSPGRHDNISPSVHPMIMGLKVVGAGLWCVPGDNEEVGAALSEALRNRLERSLRSLSYVRFGDVFVKCRRHGVLESRKVLPTCELMFMGSEEALFVHVVVRRKRVRLLSAHDMQLALAQQLVSDSPTENSLTVAVPPYGLSGRLTGCCPGDLVSVLYRSKLQAFTASSLPFRVVSSSSPSSNGGVAVQSCYAEVWVGQAQSTVEQAGFVGSSPGNTGSSQGNVDPSLDQAREADDEGQVKAGEDAKVDGKVLIYPMEAVLAPVLPPVPSRTYLRRCWLQEWAGTHWLEDSAVPGLNWNRTVVAPVKDKPQISGGGADSSSTSSSSSGSGGASIKSSSSRGSSGSSSGSSSSSESEVGTGEGELEGDADSLGSKGANTVGGGSFKRSSVSSVRNSAQNPDVAAGNSGSKRSRGKVSGLSGEPSAKVGKISTSPGGELSAMLDGGSSAAGRKGGGNTGELTLQGSMSIAVGTPREGGSQVGTPWEWTDEGMGLGMGMGMEMQTDADILAEFGDFGDFFEDDVLGFGEPPGTAESQSMIFSLADSVEGVNTPGTICMDNSDPMLLPILDFPTLEGFGGQSLLSMKEQTARGTKVSTSETTQPQSTGQMSPPTATPVVIDVLAKAEALLLFPPGYAPVELPVIKDEVSLSSTYMPETRKVIGDVTFRDVYVYSATPPPLPAVEVSKVKAEQITDPSHNEMGDGKTLHEAVTVSTGKQALNVTDPSGDSTVTNNLKFARHQILNDSGPGHSGTVMQDSPVQDSSGAGNPFLNKIDIRISAPPKSTTPVLATELECGLLQVSMLCATDFSTASINGNRAAGTPSSLSVKLPSGVKDGNSDYSQSQGEQVGRVMSKPPPAQKKKLLPSRIAGDADEDVQDGLRAAPIGVWRPVQTPKPQKTGNSTVDSRIGSSSASPDTGNMGADGNTVAIQKLNNWQSVVDAIPLLAQQAAVASDIALDGECGDGPLGWLAFQERQRHQCGCGPGINHIGCGGMFSIRHSLDNAGLEYIDPLAAEVSPATVANLLQSDFRVAISSAFGESNIDGPLTGLDWCRGRVQGDCGSATADSKEGMSAITMAAGEPVTPPHCNAGNPGVLKVPSGQDDLDLRRGSNSRILDTSSLSDQARGDDQRRTLDDAGTSDSELQPSASSHGATMIALPTPALLVGYQEDWLKTSPNVLHLWEKAPLEPYAPPKPVSYYVLCLGLDSLLTAASDFFQQLSSVYETCKLGTHAPAVTPGLTGSTSAGFSKSVLPGFMIVDSPCPSTQSAPTSTLIGDFVASMDSGWNFNEFRKSLSKVCKNVPILANPSSSQRDPDQGQSVVVYVVSPSSEPAELLQIVLDASQCFGSALSLSEKERRSSTYSQAVGTATDECSSSPVVGFSTSRFVLQVLPAEVVMKASTTLTSELSTLRDVAFGVYNKARRIQRKIALPESLHPSLPSSRVRSGILQSGTTLPGMWKDCNTVRNSAVNMGIESSLRSSWDGGWQSATSRFGDSSVTDGGSLVGDASSNEAGRFLYEPLFILAEPGIPDTNANYLSLRSGGKDSLRSSADEATGSTSGLTPGLSEPGAGAEGADGDSQGSGSQPAADLHCCYLWTDDWQWLISVWTDSRGELLDIHVLPLVGAVKDAGLQILFTQVLHQGLQLLTMAAEAGSQRPRNIMISRLGDFTERECQDWYRTVMLMGGDDSRRWPVQLWPGALNGNSSLQNQDIAYLSDRTLGLASSSSRPPSPNPSSSYTSRNKSSGMGMNLPRRQGQGLGLGSSQSGLDSKGLFQWVSSISLVSVRVEHALQTICVSDLTPSSGPGQGGSASATWPAGSVGNSSSSGITGVSTVKTLANTGASYLLVPTNTPRFLTPIIWQSPVVPPNLPPIAQLLQGSPIVSALASAYVISPPTPSPMSEFVQQAIKEEWPSTLHVGLIAFSGNPLSLESSSVSSFPHTKSLKDINKDSSNMEAHRTVSSVAAQVHALSWLTVSPSLNLRHSPLPFHCHVAQRLRRLLSYLDVEQGFPRHPHTPV
The following text describes a protein:
Function:
Important role in mitotic dividing cells. Microtubule motor required for spindle body separation.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MAGPQRATSGLPTRRTTTRQPTRRAGSAIPERQTSTASPAVSTKTAAISRTRTLKSPGEPASVLAKRKERDIEREINEDTSIHVVVRCRGRNEREVKENSGVVLQTEGVKGKTVELSMGPNAVSNKTYTFDKVFSAAADQITVYEDVVLPIVTEMLAGYNCTIFAYGQTGTGKTYTMSGDMTDTLGILSDNAGIIPRVLYSLFAKLADTESTVKCSFIELYNEELRDLLSAEENPKLKIYDNEQKKGHMSTLVQGMEETYIDSATAGIKLLQQGSHKRQVAATKCNDLSSRSHTVFTITVNIKRTTESGEEYVCPGKLNLVDLAGSENIGRSGAENKRATEAGLINKSLLTLGRVINALVDKSQHIPYRESKLTRLLQDSLGGRTKTCIIATISPARSNLEETISTLDYAFRAKNIRNKPQINSTMPKMTLLREFTAEIEKLKAELIATRHRNGVYMSVESYEEMKMENESRRIISEEQRAKIESMESSLRHKVQELLTLTSKFNDLKKDNDDTLAALCSTNDVLQQTDIVLQNTRAQLEEEEMLRCAHEETEHQLQDVGKGLISTLGQTVEDINSLQSKLDRKAELDATNAELWRASSTEVSDVTKRIDQRVEAFQTRHAKLLETTSVKVNEFIATEISNIERTRSDLSEYNRSLDAACNNAKAETSSAHEDMNNVLEEIKDLREEVKSKVGEGLNGLSAAAARISEEVIGEFTQLHSQLHTSFNNLGKDLKSIFETMATHLSEQKNEINRLRAELQSSNRQNIETTHKASAHLAQAIEEEHVAAEAEREILMSQIKALVEESRQKQFARLRAKIDGVRTEISASGDMLEQATTQHDRQIDEWVFKSEQFAKDVNASKDEIRTKLQNDWEAFDQRNSTIRKATESVHKETVRIVDVQVDDMGRQMEALDDFVAKARSQNGRYRDAHIATLDTIATGVRDSYSSIEGRVENLTGRMNQFQQEATHHHATLEESIAPLSNDVRKPLTDLSSSFQNRSLEEYVATGVTPKKRKYDYISVLPSTESHEVLKSRLRTTKEMEVLPFNSDDQLSGPSSSPGGSPSKGFVYNDVEDEVGTHAPTVTNVNPSNTGLREVDANVAARPLVYSTGEKSTDQDGSPVVSPDSATEAEGMNGPPSKRRRSNSVVADTKLPNKMLARRMAGMMEGRENVPPPGISNGRRLRGRPSP
The following text describes a protein:
Function:
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
Sequence:
MREEAMKKQGVLVAPSIMGADLACIGREARNIEESGADLIHIDVMDGHFVPNITFGPGVVAAINRSTELFLEVHAMIYTPFEFVEAFVKAGADRIIVHFEAAENIKEIISYIQKCGVQAGVAFSPETSIEFVTSFIPLCDVILLMSVHPGFCGQKFIPDTIERIQFVKQAIQVLGREGSCLIEVDGGIDKESARACREAGADILVAASYFFEKDSINMKEKVLLLQGEEHGAK
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Controls the segmental transformation of the first to the second thoracic segment (prothorax to mesothorax) and of the labial palps into maxillary palps. In embryo, required for fusion of labial lobes and development of the T1 denticle belt. In adult, expression in the head is necessary for proper development of the labium. In the first thoracic segment of the adult, required for proper development of the sex comb and to suppress improper prothoracic wing development.
Subcellular Localization:
Nucleus.
Sequence:
MDPDCFAMSSYQFVNSLASCYPQQMNPQQNHPGAGNSSAGGSGGGAGGSGGVVPSGGTNGGQGSAGAATPGANDYFPAAAAYTPNLYPNTPQAHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMGPYGHPYHQFDIHPSQFAHLSA
The following text describes a protein:
Function:
Ras-related protein which binds GDP/GTP and possesses intrinsic GTPase activity. Involved in development of cell polarity during the cell division cycle, and essential for bud emergence.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MRDYKLVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDSDRVPMVLIGNKADLINERVISVEEGIEVSSKWGRVPFYETSALLRSNVDEVFVDLVRQIIRNEMESVAVKDARNQSQQFSKIESPSTRLPSSAKQDTKQSNNKQSSKGLYNKSSQGQAKVKQSTPVNEKHKPSHAVPKSGSSNRTGISATSQQKKKKKNASTCTIL
The following text describes a protein:
Function:
Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks.
Subcellular Localization:
Peroxisome.
Sequence:
MMEGSGTENPCSRRKDYMENKKVAVELKDVPSPLHAGSKLFPAVPLPDIHSLQQPKVQLSTVPKVSCCAHCTNDPSTSPVRFGGGSGGGAGSLVPPGALLDSQSTRTITCQVGSGLAFQSAPPLQNASARNTLAGVASDFPSMCLESNLSSCKHLPCCGKLHFQSCRGNVHKLHQFPALQGCPSSAGYFPCSDFTSGAPGHVEEHVSQSELTPHLCTNSLHLNVVPPVCLKGSLYCEDCLSKPARNSIIDAAKVWPNIPPPNTQTAPVTVPLCNGCGTKGMGKETTLLLATSLGKAASKFGSPEVALAGQMLENLPPIGVFWDIENCSVPSGRSATAVVQRIREKFFKGHREAEFICVCDISKENKEVIQELNNCQVTVAHINATAKNAADDKLRQSLRRFANTHTAPATVVLVSTDVNFALELSDLRHRHGFHIILVHKNQASEALLHHANELIRFEEFISDLPPRLPLKMPCHTLLYVYNLPANKDGKSISNRLRRLSDNCGGKVLNITGCSAILRFINRDSAERALKRMENEDVFGNRIVVSFTPKSSELCETKSSNATADKVKSPKKLKNPKLCLIKDISESPSSAKAAPGKGSQANSGSATRNANVKSLQELCRLESKTGTRSSEPQQGHLRLGAPPHRSSSAAAPAPKAPGLAESVYKTNPKKESLGARSVTSSPVEKKEKEETLFQVSYPSAFSKLIASRQVSPLLTAQPWSSRASPLAFNAAHSSVGADGPDPFAHGVDVQISNLDYRLSRKELQQLMQEAFSRHGKVKSVELSPHTDYQLKAVVQMENLQEAIGAVNSLHRYKIGSKKILVSLATGAANKSLSLLSAETMSILQDAPACCLPLFKFTDIYEKKFGHRLNVSDLYKLTDTVAIREQGNGRLVCLLPSSQARQSPLGSSQSHDGSSTNCSPIIFEELEYHEPVCRQHCPNKDFSEHEFDPDSYKIPFVILSLKTFAPQVHSLLQTHEGTVPLLSFPDCYAAEFGELEIVQENRGGGVPLEHLITCVPGVNIATAQNGVKVVKWIHNKPPPPNTDPWLLRSKSPVGNPQLIQFSREVIDLLKNQPSCVIPISNFIPSYHHHFAKQCRVSDYGYSKLIELLEAVPHVLQILGMGSKRLLTLTHRAQVKRFTQDLLKLLKSQASKQVIVKEFAQAYHWCFSKDWDVTEYGVCELIDIISEIPDTTICLSQQDSEAMICIPRRERTQDEIERTKQFSKDVVDLLRHQPHFRMPFNKFIPSYHHHFGRQCKLAYYGFTKLLELFEAIPDILQVLECGEEKILTLTEVERFKALAAQFVKLLRSQKDNCLMMTDLLKEYAKTFGYTFRLQDYDVSSVSALTQKLCHVVKVADMESGKQIQLINRKSLRALTAQLLVLLMSWEGTTHLSVDELKRHYESTHSTPLNPCEYGFMTLTELLKSLPYLVEVFTNDKTEECVKLTSLYLFAKNVRSLLHTYHYQQLFLHEFSMAYSKYVGETLQPKTYGFSSVEELLGAIPQVVWIKGHGHKRIVVLKNDMKSRVNSLGPSPASHETQPSAPERILEVPESPPASELRLGVGGDGPHPAEQELLRLTDDSPVDLLCAPVPSCLPSPQLRPDPVVLQAADLIWFEEHPQEPSEIMILNQEEKIEIPVPIRNENLPPDPSSPGVSAAVPAPPSPSSETPESLLSKDPTESPAKKQPKNRVKLAANFSFAPITKL
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Sequence:
MTLKFSYFGTRGIGEPIRMLLTDQEVAFIDHRFSWEQWADIKPTMIFGSCPCLTMGDKEIVQSGTIIRHLARIHGLNGTNEEETIFIDMFYEGVRDLHATYATMIYQNYENGRQPFIQDVLPEHLARLEKLFRTYENGENFVAGANISYVDYVLFEELDIQKILSPTALDRTPQLKKFHEQFGERKNLTEYLKKRAIMKTPVNGNGKQ
The following text describes a protein:
Function:
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKKLICLFAVFLMLCGRAFALDANDLLPPEKAFVPELAVADDGVNVRFRIADGYYMYQAKIVGKTDPADLLGQPSFSKGEEKEDEFFGRQTVYHHEAQVAFPYAKAVGEPYKLVLTYQGCAEAGVCYPPVDTEFDIFGNGTYHPQTDEPASAKDRFLQPSSQNGSGALPPPKGDEGGDSRFKLSWDTLNANLLAFFLAGLGLSFTACMYPLLPIVSSIVVGDKKAGKARAFVLSVVYVQGLALTYTLVGIVAGLTGALLTVWLQQAWVVLAASALMVVLALSMFGLFNIQLPNAVQSYFQNQSSRLSGGKIVSVFIMGILSALIVGPCVAPPLAFALGYIGQTGDAVLGGLALYTLALGTGVPLIAIGTFGGHILPKAGDWMNAVKYAFGFILLAVAVYLATPHLPYYLVVALYTLLMLVPAFMLLVNGRRQKRRPKAVAFALGGILLIGGAWFGWQGANGKTTALHHFLTLNPPAEAGKSSEHGKMFADTAALKAAMDTALKEHPDKPVVLDFYADWCISCKEMAAYTLNQPEVHQAVDMERFFQIDVTANTPEHQALLKEYGLFGPPGVFVVRSDGSRSEPLLGFVKADKFIEWYEQNR
The following text describes a protein:
Function:
May be involved in vacuolar sorting and osmoregulation.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MDRQSLRTTLRAMDASNENGSAKGAKKTTIGSFVRWTFGFNSVPLTTLVTITTVLLGLLVYVSTSVNPPDVTEAQKPLLNYAWAQLGEISRYPHPYFSHDNDRVRQHILKEVYTLAGREHFEGAQIEVDDSQTDIFIQKEDVFDKSAPPGKLTYFEGNNVVVRLSSKNSDKSLGAILLSAHFDSVPSSFGVTDDGAGIATMLAVLKHALAQNEGPKRDIIFNFNNNEEFGLLGAEAFMHHPWAQNVSAFINLEGTGAGGKAILFRASDYGVASHYSAAEMPFASSVYQEGFSNGFIHSQTDYKVYTEGGLRGLDIAFYKPRALYHTRRDNIAETTKNALNHMLVNTIDVTQSMTEADSFDHADQPAVFSDIGGYLFIILPLQYIFVISCLTLAVGPIFVGFLFLLVLRKQINAGTSETILGGWLRSIVSVLVSVVATYFVVETLHLGNELYVVRSFYTPLFAGLGTFIFVNYVLLGFFHFVRPVCDQKLIILLELSVVLWVLLLLSVIHEATHKATGEYHFLILYIVVATASILGLFGHLVTSTETSTFVEGPEDEEDTVDASEATETSPLLPEASPDNAAPSIHGAVDPENQQEDKTLQKIAVSMGYDWSIQFLLVVPITFFVTFGLAASLLDGLHQTPLESEKSADFVYTTITAMSVLVGITFLPFVHKLQVFVPIVVVGVAVTASFVHILSPPFSSNAPAKMRFVQNINLDEGTSYANVLGRQDVLQEVLEYIPSTDTFKPNCSSRGDGVEICNYIAPRPWLIDGEKVSSDGDFAGLPTNLLDVKVVPVNETSSGPFDRFDGRFKISALNNRGCVLRFNTTRFKSGDVETGVSPVKMVTLRHNRVGKTGITTGSGSRFSMFGWTRDPKTGKDEFRSFMHGVDDVTLHKLDWEDPEYDIQLSWIPRWYEVGDPEDEGNEALKNRLGVTVTCSWAEYLDPSSIVDEQGRRRTMDKIPAFTELNNFSPAWSIWSNQGRGLVEVSKYVEL
The following text describes a protein:
Function:
FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation in the endoplasmic reticulum lumen in parallel to ERO1.
Miscellaneous:
MISCELLANEOUS: Present with 259 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type III membrane protein; Lumenal side.
Sequence:
MKQIVKRSHAIRIVAALGIIGLWMFFSSNELSIATPGLIKAKSGIDEVQGAAAEKNDARLKEIEKQTIMPLMGDDKVKKEVGRASWKYFHTLLARFPDEPTPEEREKLHTFIGLYAELYPCGECSYHFVKLIEKYPVQTSSRTAAAMWGCHIHNKVNEYLKKDIYDCATILEDYDCGCSDSDGKRVSLEKEAKQHG
The following text describes a protein:
Function:
Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MASLFGDDGVDDLFNDNIPTDPDQLPSDGEGEKLFADDEDNGVEPGSQDAQIVEPKKRAVRNPRPRLTVETLRGPRGIQTIEDYFKDIKFKGKGYEKTDLDEVLRRLQHWGHRMYPTYTFDDVLNNIERLGKKKPLQVHMARYRLGQLEQMRAHEAEALEEAQDEQQEGAGDEPFDEFDALLGEQIAMSRLAPPSPQQWKMSTASSNSTLATPSFSRGNAVMSTPYSGVNATFDRSGASVAPAFDRNGAPLASMDISDYGQPLPPSQPPTPAAKKLSNEQMARIAENRRLAQERLKAKQQQESGSKS
The following text describes a protein:
Function:
Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
Subcellular Localization:
Periplasm.
Sequence:
MKKPEKRKMHPKIDLHSHFITKCRAFCEIFYSFIGFLLFFFSLAANAATPEQLSMIKEAAENHVLSTVDMPAGGELVVNAANIDDRLFATDCPEPLTTNSSSSNGSAANITVLVECKPDNWRVYVPVRLTITIPLITAATPLSRGQMISAQDVTLSMVDLLRFRRQGFSTPENVIGAKIKKNIRVGDVIEQNDVCIVCRNESVVIRAGKSGMSITTKGTAMSDGVVGEQIKVKNDKSNRIIDAQVSGVGEVTVAF
The following text describes a protein:
Function:
Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate for bone mineralization. Acts in a non-redundant manner with PHOSPHO1 in skeletal mineralization: while PHOSPHO1 mediates the initiation of hydroxyapatite crystallization in the matrix vesicles (MVs), ALPL/TNAP catalyzes the spread of hydroxyapatite crystallization in the extracellular matrix.
Subcellular Localization:
Extracellular vesicle.
Sequence:
MSGCFPIAGLRCLSRPLLLFPLPHLSPRSWMCQRLWPWPANQPLPGRLPPRLPSLAPSSSSCSSLPCSQDDSRMAVQGSPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPDSLRATYREGFYNEYMQRVFQYLGEQGVRPRDLRAVYEAIPLSPGMSDLLQFVSKQGACFEVILISDANTFGVESALRAAGHFSLFRRIFSNPSGPDARGLLALRPFHTHTCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGSDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKTC
The following text describes a protein:
Function:
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
Subcellular Localization:
Cytoplasm.
Sequence:
MSVLEQEKKSGKVYIETYGCQMNEYDSGIVSSLMRDAEYSTSSDPENSDIIFLNTCAIRENAHAKIYNRLQSLGYLKKRNPNLVIGVLGCMAQNLGDDLFHQELPLDLVVGPDNYRSLPELIQRIRKGENSISLTRLSKIETYDEIEPRVVNGIQAFVTIMRGCNNFCTFCVVPYTRGRERSRDPKSIVREVQDLVQKGIRQITLLGQNVNSYKEQDTDFAGLIQMLLDETSIERIRFTSPHPKDFPTHLLQLMSENPRFCPNIHLPLQAGNTRVLEEMKRSYSKEEFLDVVKEIRNIVPDVGITTDIIVGFPNETEEEFEDTLAVVREVQFDMAFMFKYSEREGTMAQRKLPDNVPEEVKSARLTKLVDLQTSISHEQNRARIGRVYSILIENISRKSEKQLCGRTPCGRMTVFPLPQETNVSGMIGSTVSVQIESATSATLKGRILA
The following text describes a protein:
Function:
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKELQATLDKAEKTLVKVMQEDGTESDFE
The following text describes a protein:
Function:
Involved in brassinosteroid (BR) signaling.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MAAPPRASSSRAAVQATNDDASASKLSCVRKGYMTDNYVQYFVRRPVKRSPLINRGYFARWAAIRALLMQFLSQPSSKRKQIVSLGAGFDTTFFQLKEEENAPDVFMEVDFLEVTSKKAMIVAACKETARHLDSPVFAPEKGEISSEHYKLFACDLTDTARLDAVCEKANLDLSLPTLILAECVLIYMDPEASRALLRWAASKFSNAVFVAYEQIHGEDAFGQQMIRNLESRGCPLLGIHDTSTLESKMNRFLETGWKRAVAVDMDEIYNRHIDPVERRRIERLEIFDEFEEWHIMQVKEFFSCEF
The following text describes a protein:
Function:
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Subcellular Localization:
Cytoplasm.
Sequence:
MATELTWHDVLADEKQQPYFINTLHTVAGERQSGITVYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAPPPSLVNMYKELEASIPGFVRPAHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDPQRHHILKAPHPSPLSAHRGFFGCNHFALTNQWLEQHGEKTIDWTPVLPAESE
The following text describes a protein:
Function:
Major surface antigen of procyclic forms.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MAPRSLYLLAILLFSANLFAGVGFAAAAEGPEDKGLTKGGKGKGEKGTKVQDEVEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPGAATLKSVALPFAIAAVGLVAAF
The following text describes a protein:
Function:
Involved in protein export. Probably interacts with other proteins to allow the postimport or conservative sorting pathway for inner membrane proteins in plastids. Central subunit of the protein translocation channel SecYE. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug (By similarity).
Miscellaneous:
MISCELLANEOUS: Cannot substitute for SCY1.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein. Plastid, amyloplast membrane; Multi-pass membrane protein. Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Predominantly localized to envelope membranes.
Sequence:
MNSSQACFFHFSLRPISLSHPSYAFLSKRDPFLCSQPRKCLTTNLNMSRTRQGHSIQMNRRHLLMKERKSFSINYSDKFRDDSMSSEEMHTDALDVEIIPPDSQDIRNSQNSAVSNTLQDDRPKSFRNRFLDFVRISSVLNTAAERFFKSEIRRRLFVTAVLLVLSRVGYFIPLPGFDRRLIPQDYLSFVSGSVEELGEFGAEIKLSLFQLGLSPQIIASIIMQVLCHVLPSLVKLRKEGLDGHEKIKSYIWWLSFFFAIVEALVVAYTSLQYSVFAATAQVKHVMMTSSLLVCGAMTMTWLCDTISESGFGHGSSLIICVGILTGYTETLHKMLNQISGSFSNWLPYLLGLLGIFTVVTMFAVVVTEGCRKIKLQYYGFKLASASREGSPITEVEPYIPFNINPAGMQPVLTTTYLLAFPSILASILGSPFLLNMKEILNPESTVGAPPWVYYSIYAFFVFLFNIFDIANLPKEIADYLNKMGARIPNIKPGKATIEYLTKIQASTRFWGGLLLSFLATASTVLDHYLRSINQGFSIGFTSVLIIVGSIIELRRSYHAYNVMPSLSKALKRYGV
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MVSIINLGKVKPFGLSYIINSNNNNNNNDDDDYNNEIRESESSIPYEYYFCQNPLKSCFNEEQKILLQSENDETDEKGMILVNNSFFEEAQLFWYQNTVVWSSPFTVKKKFTLPLLLSSMIYPKINNAIWSHFPFLKDLSKQQQEQQQQQHHQQSEYTTSSINNDIDDYYKYLCVLHNQGLNIYNSIGNSYQIVLPCKVINIWSSKFGLLLERDSSLDSTLLAGRDRSEIPSIFSILNPLEELKPVLTFSKSNNNNNNNNEALQQEFFSDTNQTIVFSSTDYPILITYSNIENVHIIYQVSHVKPSSNAENDNTNNNNNNNNTNTNISNNQTINNENGTTTTIINNSSIVNTSKPIFNFNNVSVNDQSFDYSNINISSSSPPFSSRNNNNNNNISNNNNTNNNTNNNNTNNSTSMMQQSIQQQQQQQQQQENSSFKFLNEDKSYFFDDESEFIIKSEIIFEEVLKDSTRLKSNTKSKSIFITLDNNQKPLLCIEINSTLFCYNLFIDQKIKSTQSSSSNKNNNNNNDRNEGIEEKLKLEFSFSISSVQSSSPIFIESFYNNNEYTIPKGINQPFIPLPTHILVLNDHLLSVYWGPFKILDLPIDNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKRKPLYIKDSTFNRVTIVYSDKEEIRFKITLGKSYLVSSCLGALSSFIPMNLLASIYQDFNDFHKFRINNLLNSNSNNNNNNNNSEEENDKEWISFQILLISLLEKSLLKRPTDADTNKKIKENNHIKKEENEDDWEFLLNSNYHKNYEKGLSFLSNLNISDSSKVYPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCNIFIESINDFNFKTSLNSFIESIDDIIIALHHQYEEFKILTFNINYIYKLSKFLIQLSLHLELFNYVDYYFRDFGDLIDFINQFKIKSKTSIDISSLKLQSLLNDDIFSIYKFVYNSFNENNSETQQQQQFNKEKFERNKLTKYHFKWIYKMKSLYSIQSKINDNNSNNKNNIKYISEKLIMKMVELDIKLEDLNSISFGLSLPLRESIKYCRSNPPIDWPLKAYSLIEREELIYKFNIDDVNNVKDGLKINSLLISGGKNKLLSNSTMNHGYNSLSTSITNTLSTASSSSNEMNSNSNITSINGQSNGLPMNSTTNQMNSHQINNNGGGGGGGDDHHHHHSNSTSFDLSKFYHGQDEFYKRITYLRFDTDQRIQEVYRLLSFSNRIQINHTQENGVSDHDYLSQLQSKLLLSVQRSISLPIACGMFTIRSIKPLPTETINIPPIILNGFVGGTKTNISLDPTMVQDNMMVWPEFHNGVAAGLKVSADQTEITNTWIIYNRPKQFNPSYSGLLMALGLQKRLSSLAFTKLFEYLASGHQLTSVGLLLGISCTKMGTMDMSIAKVLSVHIQSLHPPLSIDLDVPSYVQIAALMGIGLLYCQTSNRRMTEVLLMEIGRKPINDKPLDRDSYSLTAGMALGLVNLGKGANEGSLTDLHVEDRLRSFIGISKEDSFDHMSTFFNQSYSTPSISSNRNNNDLFNNGSNNNSSSNGGGGGGGGNNNGNNSNNGNNGSSQFKKSNTILESSKPNIDLTAPGAIIALSLIYLKTNNLKISNYLSIPDTTFGLNYIRPDLVLLRILGRNLILWDSIKPQFQWIIDSVPLVVRKNVTIDRNSEKVFQEHSNNNNNNNKSRSSSSLNDFESFILIFCNVIAGAAFSIGLKYAGSLNENAFSLLMDLIQLFRKRQVYLNKCLLKKKKIEPTFDKVMRVTTETCLNVVALSLSLVMAGSGNLETLKILRMLRSRIGNEITYGNHMAINMAIGFLFLGGGQYTLSTSNIAIASLVCSLYPRFPCSSTDNDYHLQAFRHLYFLAIDPRCLITRDVDTLAPCHVPIELTILNNDTMKLETKQLVTPCLIPELSSIRSISIKSPRYWNIFINRGFVDGGVDININNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNILKNHPTIFLKRKIGHLPYTEDPEGFRSLSKSFPKSESISLYSSSKGFQKNKEEFLKSFISDPNLLAFAKHFCTNQSNEFEHFNTTILYECLTQDTPEVIPLLLLLNDIANNFEKYSNSNTTIVLENLRIIFKFYSKWNNGYYLNNNNNKNNNNDGWLIHSTFLDSISTKIDEHFEKHFLNEQSNKKLLSNYLLTGELPNSLSTSIKRKFASFISYYNLPNNKQFQSFKSLLNNNNNNNSNAIYQLWSSLGNQINFNSINKIIELSTLSFDEDS
The following text describes a protein:
Function:
Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate in respiratory regulation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSAKEGPSSKEASLGSSVTQSLPGVCEELSKTFPWTSKKRKSGLSKLCKKKTSLTENGWNSYCLSSLAARNICTSKLHNSWTQLKSTSLSCSICNASSCSLLNVLALGESTQALPTSIRNPNKAIFTVDVRTTEILVANDKACKLLGYSTQEVIGQKLSQMISKSSWDIMEALKEEHADAEEHENVIPGIVVDVISRSSEKIPVSVWTRRIKTPQNKYCVVVLEPVERLSATVFFTSNGEIVSCDPLFAHLHGYAASEDVIGHYITDLIPSIQIPTPGKKIPQNIKIQRSVGRAREGTTFPLSLKLKVNLPDQDSILVRDNDEPEVEADISENNTPSFPVNCSFCATIWVFTTINGLITVQADGTIYGISNTFSLMLFGYEKKELLGQNITFLIPGFYKYMDKAGNSSLQLRRSRGSSDAENESKFKQTRMDGCGTVEINEGITPYTAGDMSSLGLQEQELTGSDEGQFHTGNGTQQGNGGSLLSFLSPPPQASTPVNGRDSTVSMNVSVADQILSSERVSEGVSTDHQATKPVNSQQCEISSPNKSQSELYALESRAEQQEKDFVGKSCGLLQGEEEEEEGDTIDTHSFCFPYEMMESVPIIKSDGAELQNREERQLDGEFNLPSLVLPHAEVSTSLNREDTADSHVLDPDVVFPSENLEDGHFTETAKPISSQENEACFPQQLHMEPSVLEDETKVQERVLSRNSADFLQKEGEDSLSDKHASGLLPETLKCQYTPTSNGKNGSLLDDETLAMNILDDFGHEISVPCDASDPTLDEPMYNTVCHLQETHGPLESRARNGGLGNVPLENLSSDLPAFLYEERSSNSPVSMGLLSPCDDLAVVEGKTTDVTDSLCCDLKDLGIRSGEVCSATPELTQLSLNEEDHGQFLNQTNNTSASNQIDLLLKGESPTGCQRNLLASKHSGLSSLDVARNCSSGSGESTGRHLEIHSPGNEERSQEEFMALKQVTSTPVKVLSPGISLNNEIHEGSYSGNCYHRDGSRLSILFEVKRVELQDPAALFCIWVMRDHFQSQKEAAAKTHLLLSRLASSSHTVVDVSAVNLAELIKTTPLFENSRRVEELEKLKACEGEYEKKYDTLGLIGKGAFGFVWTAKCRKDQKEVVVKFIWKERVLDYCWVEDPELGTITQEILILRKLQHPNIIKVLDVFENRQFFQLVMEKHGSGLDLFTFIDNQPNLDEPLASYIFRQLVSAVAYLRCQNILHRDIKDENIIIAEDFTIKLIDFGSAAYLEPGKLFYTFCGTIEYCSPEVLSGNPYLGPELEMWSLGITLYTIIFGENPFCELEETMDPVLRPPYSVSDGLMDLLSGLLQPFPEDRTTLEVVVKHPWVTQCVNLANYTWEEVFASVKSEGSRFKIFSTVCSHGGIWAAPSIESEQSFNDDLYNFEQPNPPPTRIGTSLEQEPSTSLQCQD
The following text describes a protein:
Function:
As a component of the decapping complex, involved in the degradation of mRNAs. Promotes P-body formation. Translational repressor.
Subcellular Localization:
Cytoplasm, P-body.
Sequence:
MAAEAPPSSSSGARAPAASGGAASPETYLGSLISLTSKSEIRYEGVLYNINTEESSIGLRNVRSFGTEGRKKDGIQIPASDKVYEYILFRGSDIKDLQVKSSPPPPQPQPAPLHNDPAIIQSHYPQAASASSSLPSAGGAVLPDLSSQAAQYGIQRPSFQSNIPLYQPGNVQWGSSGPPPAGSVSALSVPPMYWQGYYAPPGLPPHLQQPPFLQSTPGLSVPQTLQYPGLNPSLPSGQQKLSELQPPLLQPSASGQGPTSSITPATTAPSASLLGPDTSKPLLPNMVPLFTPPVPSHGAPLPLASQPIPMTETSATASQSLASLVSSKTAVAPGSTLSKTAVVPGSTLSKTAVVPGSTLPKTAVAPGSTLSYQTASQAISSTVASSTPAGMEMPAPLLASSGQLLQNAPSMLSSSQSMQTPLHMSNSIGKPVDPKPKAAEPLLPDPPARALPENNEPILPLPKQTPQKYNGAGSHSQQQHNFRGRGRGRGSAFSQSVTKFTEEFDFTAMNEKFNKDEVWGHLGKKSQSRDKDGELGDDVFDEDLQYEETDNPELDVKPVYVKDDFFDSLSGGTFGRGGQNGRPRFSEQRKMDTETFGDFPRHRQPYRGGGRGYRGGGGRSRGYYGGRGYGNTGRGGGQENYYGGGGYGNMGRGGQDNSYPQRGSYGRG
The following text describes a protein:
Function:
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSLKGKTLLVSTITLAAVVLVALLGGSVFLKAGQNVRKAFEEYELAVEALDKLGELETKVALFVNNAAKIEEVSSLFNELKKVADKIPSLKEHMDALERNISEIISGKTEVVSRIQSSVDQVKEDIMANLDRTRENLDKEISYSSELIRNVLFIVLPIVAVASGVFLFVMISRSLRLLKPVMEASRSLRNNDLTINIQEAKGKDEISTLLNEFKASIEYLRNNLKDVQTETFSVAESIEEISKANEEITNQLLGISKEMDNISTRIESISASVQETTAGSEEISSATKNIADSAQQAASFADQSTQLAKEAGDALKKVIEVTRMISNSAKDVERVVESFQKGAEEITSFVETINAIAEQTNLLALNAAIEAARAGEAGRGFAVVADEIRKLAEESQQASENVRRVVNEIRSIAEDAGKVSSEITARVEEGTKLADEADEKLNSIVGAVERINEMLQNIAAAIEEQTAAVDEITTAMTENAKNAEEITNSVKEVNARLQEISASTEEVTSRVQTIRENVQMLKEIVARYKI