lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRPSGDEDRARRRRRRRRRRDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMTEFNVFTFVNLPMCGDH
The following text describes a protein:
Function:
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.
Sequence:
MTESGARFLHVGDIASLYAEGTVCGFICTLGLVDDRCVVQPDAGDLANPPKKFRDCLFKICPMSRYSAQKQFWKAAKPTLSSATDAVLLKKLHDDVQRIQTIFITCKYSICMSMHVLYYIPYVCASDEEASHFLSSHAAEMEKKQNEQEYGKLLGTTIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDTNGNEGSWFYVVPFYKLRSVGDNVVVGDKVIVNPVNAGQPLHASNHELVDNPGCKEGDVIRLFHAEQEKFLTADDYKSKMHVFLRTTARASASSATSSKALWEAEVVQHDPCRGGAGRWNSLFRFKHLATGKYLAAEIDHDPTPDVTREKLRGSAGGPVYHLVAVPHGHDIASIFELDPTTLQHSDALVPRSCYVRLRHLCTNTWVHSSQIAYDSDEDKPVMLKVGTASIREDKEAFAIVPVPASEVRDLDFANDASKVLADFASKVEKGTFSQTERRFVTQLLTDVVYFIVDMEPVGDALSVTTNKPDRERQKLTREQNILEQVFRLLKAPFSDIGTGCLLRMEELADQRHTSIRHICRLSYRILRHSQQDYRKNQEYIAKQFGFMQQQIGYDVLAEDTITALLHNNRKLLEKHITAKEIDTFVNLVRRNKEIINEESDSKVYLCSRDGNFSKSQRDLAQGAHEGNREDIELLKYYRYQLDLFSQMCLDRQYLAINSLCKQLDIDLIRRCMSDEALPCDLRASFTRLMLHMHVDRDPQEPVTPVKYARLWAEIPTKITIEEYDKSLMEQKVKEDMTSKFASTIKFVEAALPNPQWPNSVIKSIHGVGSVMTNIIVGNNASTNRRDAPAATHEMVSQVGSIGKTKSEDVLVMNTKLKIIEILQFIMDVRLDYRISCLLSMFKREFGEKGATTNSVAGTTKPDGCGGRTFLRVLLYLTMHDYAPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVSKSDIENYKQIKQDLDQLRLLVEKSELWVFKSKSNAKGDKKKKSKTDSKKSAEKENNNAKNQEKNKANDNTDVNLEKNIQAIIEKNAALGRYPSIDLEQSFGDNESVQNYSKIQQILERLSKLCISESTNKNRKHEQRLLRNLGAHTVVLELLQIPYDKLLEAETARSIFLNNSNLCNEITERVVQHFVHCIETHGRHVQYLKFLQTIVKAESQYIRKTQDLVMAELVNVGEEVLLFYNDKASFDGFIEMMRSERERFEDSGALSYHINLVHLLACCTEGKNVYTEIKCHSLLPLDDTVKIVCDQDCLPEVKIAYINFLNHCYVDTEVEMKEIYTSHHMWTLFENFLIDMALVCQSIDRRHADLRLEKYVTETIMTIITSFFSSPFSDSSTTLQTRQPIFVKILQGSYRVSLCRWLNGQQKYHVETCIRVLAEVAKNRGIAIPVDLDSQVNALFSKSLLAMKSTKQWISHSKNRRDSINSQNRDYRNIIEGLQDIVSLFEDQLQPLVDAEMSVLVDVLYRPELVFPVQTEARTQCANGGFISKLIQHTKKLLDKGEENLCLKVLQILREMMTVDVGFNNKGEELRNNLLIRYFGKNFRRPSIDGSLKLTSNGEISTGNNSRAHGVISLGKPKMDRISVHVDSHPGNVKLSRIDMTLCQIQCQLDKNGASDLVIDLVMTSISRRVFLESIELGIALLEGGNSVIQASFFDRFCQSKSEAFFKCICDRMKEAQLEIKNSISLMTTDQVTDGQKSNYGTQGNGSNTRSSGHNLSSSSGAVSSEMLAGTGVQNLKSDAKKAMMAPEIMCMGPILRFLQLLCENHNLDLQNYIRKQDNKTNYNLVLEALQFLDCICGSTSGGLGLLGLYINEHNVGLINQCLESLTEYCQGPCHENQNCIASHESNGIDIITALVLNDINPLGKHRMDLVLELKVDVCRQAYKQGMSERAKIDIGEDDEENQISPLEVGHNIFILAHQLVQHNKDLQSLLKSDPEDEVVNAQEGALQYYASHTAQIEIVRQDRTLERIVFPVPPLCEYLTEETKNRVYHTAERDDQGSKISDFFLKGDDMFEEMQWQKKLRSHRIFFWFSSQMTVWGNICFYFAVLINLFVAFFYPFSVNTRDLDPRLSLLVWTAMIISLAVILTAPRPSGIRTFIGSTILRLIFSVGLDATVALLGLLNVTVKITFMVSWLANKGKISKGYWQLLSDVELIYHLVYLIICILGLCVHEFFYSLLLFDVVYREETLINVIKSVTRNGRSILLTALLALILVYLFSIVGFLYLKDDFIIESEQRVIKKAKNSSSGSCPDGSCKEAPVNGKKTLTSLLLHNDRNIKFATVMKGQEDDDDEIEYDSDKERACDTLLMCIITTLNQGLRNGGGIGDVLRKPSSREPLFVGRVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQQKEEILKNTCFICGLDRANFDNKSVTFEEHTKEEHNMWHYLYFIVLVRVKDPTEFTGPESYVYEMIKRHDLDWFPRMRAMSLSVEEIDSEQNELRNLQNQLEATNTLVLNLSQQLNELKDQMMEQRKQKQRIGLLAPQHTANIMSGHNM
The following text describes a protein:
Function:
May be involved in glycolipids transfer.
Sequence:
MEGTVFTPCLEGMKHVKSDQGEMLTKPFLELCKTILPVIDKFGAAMTLVKSDIGGNITRLEKNYLSDPDKFKYLYTFVQVEIESKIAKGSSSCTNGLLWLTRAMDFLVELFRNLVAHQDWSMPQACADSYQKTLKKWHGWLASSTFSMALKLAPDRKKFMDVISGSGNIQADMERFCAEFGPFLHDNHKFLASVGMDDMKAS
The following text describes a protein:
Function:
Alternative, nonproton pumping NADH:quinone oxidoreductase that delivers electrons to the respiratory chain by oxidation of NADH and reduction of quinones (By similarity). Utilizes NADH exclusively, and electron flow from NADH to ubiquinone does not generate an electrochemical gradient (By similarity).
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Membrane-bound (By similarity). Interaction with the membrane is probably mediated by amphipathic helices and electrostatic interactions (By similarity).
Sequence:
MKNVVIVGGGAGGIELATFLGNKLGRQKQAKVTLVDRNATHLWKPLLHEIATGVMDDGVDSLSYRAHGKNHFFSFEQGSIIRINREQKYVELAPVYGQEGDMLVIARRIPYDYLVIAIGSKSNDFNTKGVADNCIFLDSSKQALRFQHKLLELFLKFSENRALDDIGEEEFKQKLVDENKVNIAIVGGGATGVELTAELYHAAEDLSSYGYGKIDSSCLQVTLVEAGTRLLPALPENLSAAVLDELKEMGTNVQLNTMITEAQPNTLITKDGGEIKADLIVWAAGVRASTVTQQFDGLEINRINQLVVKDTLQTTVDDSIFAIGDCAALIQSNGKLVPPRAQAAHQMAKACAKNIFALFENKPLKSFKYNDKGTLVSLSNFTALGSLTNKFGKNPLTVQGKFAQFAYVSLYRMHQHALHGCIKIGLIILVDKLNRYLKPRLKLH
The following text describes a protein:
Function:
GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Involved in protein trafficking by controlling ARF1 activity; may participate in COPI vesicle formation at the Golgi complex.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing AGD7 show a relocation of proteins from the Golgi complex to the endoplasmic reticulum.
Subcellular Localization:
Golgi apparatus.
Sequence:
MAAARRLRTLQSQPENKVCVDCSQKNPQWASISYGIFMCLECSGKHRGLGVHISFVRSVTMDSWSEIQIKKMDAGGNERLNNFLAQYGISKETDIISKYNSNAASVYRDRIQALAEGRQWRDPPIVKESVGGGLMNKKPPLSQGGGRDSGNGGWDNWDNDDSFRSTDMRRNQSAGDFRSSGGRGAPAKSKSSEDIYSRSQLEASAANKESFFAKRMAENESKPEGLPPSQGGKYVGFGSSPGPAPRSNQQSGGGDVFSVMSEGFGRLSLVAASAANVVQTGTMEFTSKVKEGGLDQTVSETVNVVASKTTEIGQRTWGIMKGVMAIASQKVEEFTKEEASTWNQQNKTEGNGYYQNSGIGNKTANSSFGGSQSSSSGHNNSYRNSNSWDDWGEENNSKKEAAPKVSTSNDDDDGGWAGWDDNDAKDDDFYYQPASDKKSVGHNGKSDTAWTGGGFL
The following text describes a protein:
Function:
Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes.
Subcellular Localization:
Nucleus.
Sequence:
MAALRGGAVLPAAGAGVGAGVCGASTGAASRGPAGGGASRQPALRAGSPLQCFSFEEDDLNLSLDAETIPEAEEILGTMQNYLDSSVISIIEDLSLSEGKACLDAQNELSLLTAITEILDSTDDETLSPFDTIMDAELLTSLRERENPSFQKFLSLSRPVLECKSPALEQPKGLWSLSSGGSMPETGKTNVDLAWDCIAHSLEDPSPPKKQTCSTPRVERKQGRPRAHEQLPLQRSDGEEEDEEAASSPELDSSMEAAEFCMNAPEVVAEEHEDPCVINTGDVSLSELVKSMHPYCLPTFTVCLDPESEPVAKELLNGPVVLEIVPREGENMEIPVVLQPLAPSFPDLEPQLLGTEGDAESIPVHGEEPPGDPAAETGMEEEEKPPGQEPSCAAPYSNTPVETAVSSKREICEKGRGRERARKSRKKKAEEGLSEDGRPGRGCVAHRLRSGRSRRAARPSLQVSDFLARQLEQARKEGQMELHAERAPRPRGRPRGVAGVSLPTKEPPELPKGLEPEMTDTVLEKGETAVPVEKTTEEPLAAKQPIPVEQEDKGAVQPDVGMPKQDVGVEPPQSVPAAEPSETLPKEAKPKALSLREYRMRMQHRQSSTGSRKEGKKQAASKWPSVPEPPTELADIPCLVAPARPPTETPSAQKSLEKSAGSPAGPPPANKAPAAPVPAPVPAPAPASAPAPASAPPPPVTPIPFVAPTMPPAAGVAPPGMPSPATTGAYAMYPSVPSWPCFGPQPLGCHALPPPPGAGPPGTFHMMHGLPPPPMAWPPPALPPPPPFVPGGPYGPVGWAPPSYWPGIPIPPPPVPPMAYGDPALQGAAASSVPAGGCPSTALLHGQAPPAPELPAIPVQPSPSREMETAGSQARPGVSRVSNPRRQARMVGESSFPKGPLAPAPTQPPVTPSGAAAQPSRAPPAAPAPNVAAPAQPVEEPPPLAPIQLSKAPPAVIPAEVSAAAVPAGGSPGTYPTEEPAGPAKTPVDKTPPEPPSHKPIIQALAPPPKPCRESSKPPAARPWRHQPLISPAQPSDSSQDIVQAFISEIGIEAADLSSLLEQFEKSEAKKEEAPVQPPEERRPARSAGSEPQPERKPPDSLQASELANVAGLTPPATPPHQLWKPLPTVSLLAKTKSPVSAPQEGIQRTAKLAKAKALPQSRLQGRSPAPGSAAPSHVCSGDHDYCIPRTAHLENSSIAGTQPPATESGSRWNVKHHRDITIKPISSLTKRTLDQPKPAPATTVGPSQESPGAACPTPLDYRTSVPSKAITGGDSPATSVLLSPAASPCRDQEVWTSSTQPGRVAAKKSLRCYRRPQDSPSPSAGSWRAGRSRASRSFSSSSDGASESSSSSSSSRSRSRSLSPPPKRWRGYRSRCSHSSSSRSSCGSCGRSRDRSSSSSSSSSYSSRSPSRRQSRSRSPSPCRRSNRRRRYSYDAQDHYQRQRILQKERAIEERRVVFIGKIPSRMTRSELRHRFSVFGDIEECTLHFRSEGDNYGFVTYRYAEEAFAAIESGHKLRRPDEQPFDLCFGGRRQFCRRNYADLDSNREDFDPAPVKSKFDSLDFDTLLRQAQRSLRR
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Domain:
The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.
Sequence:
MEKFLKYEIKVNNNQPTNTNPNYGIFEVAPLESGFGITIGNAMRRVLLSCIPGASVFAIAISGVKQEFSNVEGVLEDVTEMVLNFKQLVVRISDLLFEDGEMIEPPLERWPVLKVTAEKKGAVYAKDLECPAGFEVINKDLYLFSLQKDMKLTVSVYVKQGRGFTSFLENRELINSLGIIATDANFSPVLHCGYEVQEVKTSKQKLTDHLTFKIATNGAIKAVDAFAMAAKILIEHLNPIVSVNESIKNLTIIQEKAEERKVKSFAKQIEELDFTVRTFNCLKRSGIHTLQELLSKSLTDIREIRNLGKKSEREIIKKVQELGLKFRS
The following text describes a protein:
Function:
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
Subcellular Localization:
Mitochondrion matrix. Nucleus.
Sequence:
MYLSSFSVSTARCCKNVIIRNTLSKNGIACPSFTFSCKHSSTSSTSLSLGLLSRSRLKIVTENTNFLSICNVRRISSGKNWLNLRCTKTFYSDPFQSESQIRLSRSKWSFSSQFGIQRRAASSHWEMAADKAKLRFLKNRERRAQLDKAPQQSGVVSLQIVGNGSIDCPPSVLIITDTSRYIFNCGEGTQRLLMECGTRNLSKLEHLFLTRMSWENVGGAIGMTITLKNIGIPRVTMYGPPNMEEFKKAIQIFAKHEAIDINLKPYSEGPFMNDTMVVTAVPLFSTKNEDTIVSTETDDNQGEEGCSETSDREDNVSPVPSEESGVKRKAASPLDVIADMNVKLQSTGASAKKRKTERLPDMTIAYVCKLHDKPGKLLVKEAVQMGLKPNLHFELVKSGKSVTLDDGTVVKAEDCLGPVIPGQVFIVLECPSVDYIEPIVSNEVFTRHFSDCGEDAASLVLHMCPEEVLHDERYQQWITRFGATAEHIIFNESCESLRLDASRGQQTLLNQLHEGIFPILPTHTLKATPIPPQIKINGSESIAKVTYAEIYNKLHLKPAKGWERDFIISEDRQRFLDELGPLKGFQESLKTLKATLEETKSDHTESTEQKYPEVVFLGTGSAMPNKARNVSGILLNFSENKSMIMDCGEGTFGQLCRYYGDKVDGVMASIQCIFISHIHADHHAGLINLLKHWKRVTKSDDSGNNLILIGPKRMFIWLNLFDQHCESFIHRTRFVELADLNINQQGERSRHEASLLSRFNLKEFNTVYVRHCANAYGVTLTHQDGWKMVYSGDTMPCDNLIKAGKGADLLIHEATLEDGMEEEAKKKRHSMISQAIEVGQSMEAKFLLLTHFSQRYPKVPLIETSSTSKIGIAFDNMRVSFSELDLLPQFLPTLKYLYAAEIQELEVLREKKAERKVINKQMTKKKMPSTS
The following text describes a protein:
Function:
Global regulator of respiratory functions in yeast cells. It belongs to a complex that binds to the sequence CCAAT located upstream of genes involved in mitochondrial electron transport.
Subcellular Localization:
Nucleus.
Sequence:
MNPYEPVEGLYVNAKQYHRILKRREARAKLEERLRGVQTTKKPYLHESRHKHAMRRPRGPGGRFLTADKVSKLRAQEAAEAAANGGSTGDDVNATNANDATVPATVSSEVTHTSEGYADSNDSRPSSISNSSESPAPINSATASMSPANNTSGNNITSPNVRGELDMSGNIAMSGGPTNTASTSGPVPHDMTVLPQTDSNTSNLMSSGSQLGSFATASTNGNNSTTTTTSSAAHPGSFHKGTNDYSSTLAGNEHSAFPGLDVYHDDSVSAGAAFIPHNPMDSIDHLDVNDPTATGLPVLPASDIDPLNLTGNTQDSMIIGQQTYPSHGSSGTMK
The following text describes a protein:
Function:
Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation; This promotes the activity of RNA polymerase II.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody. Nucleus.
Sequence:
MEVPAAGRVPAEGAPTAAVAEVRCPGPAPLRLLEWRVAAGAAVRIGSVLAVFEAAASAQSAGASQSRVASGGCVRPARPERRLRSERAGVVRELCAQPGQVVAPGAVLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVHSVPELMVSSEQAEQLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLGRGEPMLHTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFQGTGDMNAPPGSRESQTRKKVNHSRGTEVSEPSPPVRDPEGGTKAPGVEPSNGLEKPARELNGSEAATLRDSPRPGKPDERDIWPPAQAPTSSRELAGAPEPQGSCAQGGRVAPGQRPAQGATGTDLDFDLSSDSESSSESEGTKSSSSASDGESEGKRGRQKPKAAPEGAGALAQGSSLDPGRPAAPSLPGEAEPGAHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAETESQNSELSGVTAGESLDQSVEEEEEEDTDEDDHLIYLEEILVRVHTDYYAKYDRYLNKEIEEAPDIRKIVPELKSKVLADVAIIFSGLHPTNFPIEKTREHYHATALGAKILTRLVLSPDAPDRATHLIAARAGTEKVLQAQECGHLHVVNPDWLWSCLERWDKVEEQLFPLRDDHTKAQRENSPAAFPDREGVPPTALFHPMPVLPKAQPGPEVRIYDSNTGKLIRTGARGPPAPSSSLPIRQEPSSFRAVPPPQPQMFGEELPDAQDGEQPGPSRRKRQPSMSETMPLYTLCKEDLESMDKEVDDILGEGSDDSDSEKRRPEEQEEEPQPRKPGTRRERTLGAPASSERSAVGGRGPRGHKRKLNEEDAASESSRESSNEDEGSSSEADEMAKALEAELNDLM
The following text describes a protein:
Function:
Interconverts GlcNAc-6-P and GlcNAc-1-P.
Sequence:
MNEEQQCLLLSSASRFWPPKGVKLSYGTAGFRADASLLQSTVYRVGILAALRSLKTRSVIGLMITASHNKVSDNGVKIADPSGGMLSQHWEPFADALANAPSPQHLLLLINEFVEKEGISVDGDWHVEVLLGRDTRPITVSWRSLTLRGQMRPMWSQLGCRQPDTPKTVTLWLKSLLQTLFYNLEGIRGVTSIVGAVATDMGILTTPQLHWMVRARNKGMKASEQDYFEQLSSSFRCLVDLIPAEKCKFDGVNDKVVVDAANGVGGVKLKYLGKLLNGLIIEVRNSSEDGGVLNDGVGADYVQKEKVLPNSFGSKDTGIRCVSLDGDADRLVYFIVPPESSGRIDLVDGDKILSLFALFIREQLSFLNEKEDMKNCHQAHLGVVQTAYANGASTNYLKLLGLEVNFTPTGVKYLHEKATEFDIGIYFEANGHGTVLFSESFIESLEARTNEISLGSKGSEGEKAALRLLAVSKLINQAVGDALSGLLLVEVILQHMGWSINKWNELYHDLPSKQLKVKVADRTAIVTTNAETVVVSPPGLKEAINEETAKYPQGRCFVRPSGTEDVVRVYAEASTPEAADTLANCVAKLVDQFLGFNSS
The following text describes a protein:
Function:
May function as an adapter protein in a pathway that mediates recognition and phagocytosis of apoptotic cells during normal development. Promotes engulfment of cells at both early and late stages of apoptosis. Required for actin reorganization around apoptotic cells. Plays a role in protecting dopaminergic neurons from oxidative stress-induced degeneration. Mediates recruitment of E3 ubiquitin-protein ligase trim-21 to the apoptotic cell surface which promotes ubiquitination and degradation of ced-1.
Subcellular Localization:
Cytoplasm.
Domain:
The PTB domain is required for interaction with trim-21.
Sequence:
MAKDIYKTFKRSVSGIVGGNNINGEGSSSPSTSAPQVKYRGGTGRTWIHPPDYLINGHVEYVARFLGCVETPKANGSDVAREAIHAIRFQRDLKRSEQTRETAKLQKVEIRISIDNVIIADIKTKAPMYTFPLGRISFCADDKDDKRMFSFIARAEGASGKPSCYAFTSEKLAEDITLTIGEAFDLAYKRFLDKNRTSLENQKQIYILKKKIVELETENQVLIERLAEALRANSKADYENTGPPIYPGLGPPALPLSPMPQGPPPNIPPSSIYSMPRANDLPPTEMAPTLPQISTSSNGASPSVSPASTSPSGPAPSIPPPRPPALAPPPPVAPRRNPVVSPKNSTAGLLDGLELGSAEPAKKAPSNIFDDSFDPRAGEKKSTAAEYNPFGADFLSGIQNGKEAPPSASAELLASEAIARLPKPESSSVPPKKTAAEYDAMINEVEKKLAAMSSGSFEFGQLQTGDLGGIEGESDYGTPSDRLNPKMMNLKQ
The following text describes a protein:
Function:
Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, monomeric IgG binding to FcRn in acidic endosomes of endothelial and hematopoietic cells recycles IgG to the cell surface where it is released into the circulation. In addition of IgG, regulates homeostasis of the other most abundant circulating protein albumin/ALB.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Endosome membrane.
Sequence:
MAGPLAPRGPARSPCLLLLFFLLLLFLLRLPLALGSAALWSLHYHFTALSQPGPGLPRFWASGFLGEELVVTFKAAGTGGQEGQAEAQGPWKFELLPPWAWEQETTDLRSRHAEMEKALAAIVEQAGPGIGSHTLQGLVSCALRKDNRTEGVSRFGLDGRDLLTLDHLTTPEATWVGAGPAADSVRKAWGSQQAEKEVGFLQVTCLKRLQNHLKTGRGNLAWTEAPTVRKSTRRSPGQNTTLLCRAFTFHPPDLRLSWLRDGAVLPGETRAQAPLPSGDGTFQTWEVLKVPEGEEWRYACRVEHQGLAQPVILTWEQRGPSPAWLFAASVLILAAGAAGYLVWRRRKLGPPALWLRLRGEDTGSLLPDPATSDSDVPSAAI
The following text describes a protein:
Function:
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. It probably carries the active site for 3'-splice site cleavage.
Sequence:
MEESVAGEVTVPADPVEDSASGLGFIMKGSSFTDSSSVASTAASHASTADTSLFDSTPASPAPSVVGSIARPSLGQRHFVTPTTSYPPIPNPLDASSAQLPTVPKSYPLFRYLHSLGYYHMPGLRFGCHYNSYPGDPLRYHSHFAATGMGWDDEFELLDIVGGGRLATGTKKAYMIGGEDVDVVKKKQLASEEPDLFSDDTKEEGREVRAFSIEWAAI
The following text describes a protein:
Function:
Acts synergistically with RAB5A and VPS9A to regulate dense vesicle-mediated post-Golgi trafficking of major storage proteins in the seed endosperm during grain filling and maturation.
Subcellular Localization:
Prevacuolar compartment. Golgi apparatus, trans-Golgi network. Protein storage vacuole.
Sequence:
MTPQLQPKQMHWARADSSDFGGQIPAPRSGHTAVSIGKSKVVVFGGFADKRFLSDIAVYDVENRIWYTPECNGSGSDGQAGPSPRAFHVAIVIDCNMFIFGGRSGGKRLGDFWMLDTDIWQWSELTGFGDLPSPREFAAASAIGNRKIVMYGGWDGKKWLSDVYIMDTMSLEWTELSVTGSVPPPRCGHSATMIEKRLLVFGGRGGAGPIMGDLWALKGVTEEDNETPGWTQLKLPGQSPSPRCGHSVTSGGPYLLLFGGHGTGGWLSRYDVYYNECIILDRVSVQWKLLATSNEPPPPRAYHSMTCIGSRFLLFGGFDGKNTFGDLWWLVPEGDPIAKRDLVPNVDSDSKPSNVTGGAQHSASQESQAGESPMIDLAKRLGISLSLEASASFVDEINDKELIELSSMLFGESPPTGDQHACIQALRDHWTSIPANSIQLQELGPLLRDYQRLILRRYLENSFTSFYEKEVHRFFHLKNASELRMDDIPILLMEYGKLLST
The following text describes a protein:
Function:
Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
Subcellular Localization:
Membrane; Single-pass type IV membrane protein.
Sequence:
MSEKHSLLQVSPHRELVFTGPFSDVVTAHMTLKNITANPVCFKVKTTAPKQYCVRPNSGLLKNGESKQITVMLQPLEGIPTDAGRHKFMVQSCVAPAEDLQDLESIWKIVDPAELTYSKLMVTFTTTKRSLSTVTKKHLRLLDKHSKLIHIIFYLKIFAIYRELGSSFSAPSSQQDGTVASLRKSLKSTIDEKEELQKKVHGLEQEIEVMLKKNRKLQQNQSDGALVEGAFPTLQVVLIAVAALLIGLIFGHLF
The following text describes a protein:
Function:
Probable component of the chromatin structure-remodeling complex (RSC) which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. Probable component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Miscellaneous:
MISCELLANEOUS: Present with 1550 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MDPQTLITKANKVSYYGNPTSKESWRYDWYQPSKVSSNVQQPQQQLGDMENNLEKYPFRYKTWLRNQEDEKNLQRESCEDILDLKEFDRRILKKSLMTSHTKGDTSKATGAPSANQGDEALSVDDIRGAVGNSEAIPGLSAGVNNDNTKESKDVKMN
The following text describes a protein:
Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MAPLLRKRQANRPMVALLLFLCASEADTGTVRYSVAEEMESDSFVANVAKDLGLEAGELLARGARLVSDDSKQHFRLHRKTGDLFVKEKLDREELCGKADPCVLRFEIVLEEPLQSFRAEVRVFDINDNAPMFPNHGPVLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSANAYFHLHTRFRSHGPKYAELVLIKPLDREEQPQVCLTLTAVDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVYRAQILENSPNGSLVTSVSATDLDEGTNREIVYSLAQNPEGILQTFHINFENGEIRLRGPVDFEAIENYDIDVQAIDGGGLSAHSKVLVEVMDVNDNAPDVLITSISNRIPEDSPLNTVVALFGVRDRDIRVGGKITCFIQGDLPFTIKQTFRNSYSLVTGGTLDREKVAGYNLTIVAMDSGTPRLSSETIIEVVISDINDNPPVFKEASYTMTVRENNSPAVFIGKVQAEDLDSEENAQITYSLLPPESGDLSVFSYISINSNNGKLYALRSMDYEAIQAFQFVVKAVNGGPLPLSSQIIVRVVVLDVNDNLPMILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQNSWLSYELLKATDLGLFSVGRQSGEIRTLRLISERDSMKQKMVIAVRDHGQPSLSTTATLNILLVDGFSDPYVQLRDHSKRERKTNPSTKYLVISLAVLSSLFLFSVTVIFLIHIYQKIKYREKQFTTSEHFYYDCNFPNNLMDGQSRETLGRVCPYEVGSATGTSNSEFRFLKRFMPNFPAPSGVEERNKEETRSHLPSSLDLDSPRSEDCPRMSDEYM
The following text describes a protein:
Function:
Catalyzes the reversible NAD(+)-dependent oxidation of scyllo-inositol (SI) to 2,4,6/3,5-pentahydroxycyclohexanone (scyllo-inosose or SIS). Is required for SI catabolism that allows B.subtilis to utilize SI as the sole carbon source for growth. Cannot use NADP(+) instead of NAD(+).
Sequence:
MEHQVRCAVLGLGRLGYYHAKNLVTSVPGAKLVCVGDPLKGRAEQVARELGIEKWSEDPYEVLEDPGIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSLEESKAASEKVKETGVICQVGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGAPPAEFIKHSGGIFIDCSIHDYDIARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALTYIEFDSGAAGDVEASRTSPYGHDIRAEVIGTEGSIFIGTLRHQHVTILSAKGSSFDIIPDFQTRFHEAYCLELQHFAECVRNGKTPIVTDIDATINLEVGIAATNSFRNGMPVQLDVKRAYTGM
The following text describes a protein:
Function:
Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVKLPSLTPYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAIEMLASYGLAYSLMKFFTGPMSDFKNVGLVFVNSKRDRMKAVLCMVVAGIIAAVFHTLIAYSDLGYYIINKLHHVDESVGGKTRKAFLYLAAVPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILLHSHLECREPLLIPILSLYIGALVRCTTLCLGYYKNIHDKIPESSGPEIGGDATIKKMLSFWWPLALILATQRISRPIVNLFVSRDLGGSTAATEAVAILTATYPVGHMPYGWLTEIRAVYPAFDKSNPGSKLANSSNPVSKTHIKNXTFACMALSLTLCFVMFWTPNVSEKILVDIIGVDFAFAELCVIPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSILRIIVLISSLIVLPYLGVHGATLGVGSLLAGFVGESTMVAIASLYVYRKQKKKSETENAVEGEDSAMTDLPHNEELTDIVEIKEDGE
The following text describes a protein:
Function:
Plays an important role in the control of DNA replication and the maintenance of replication fork stability.
Subcellular Localization:
Nucleus.
Sequence:
MDEQEDSVSTSRRQQPRFLGDDAMDEETATNLPESLDRFFAGLEGEDQDEALPEMLDHAAIEASLAAKKVEALDPFALVSGEQAVKKKTARRPTVKLDEDRLLDPKLGIPHLISLSKNFKPSGKGNEKEDLKRLLKLYRLWTHSMYPKGSFKDTIETIGKLCHKRKMRNAMRGWREESTGGTKPAKKKAKLDGSTEVEPGLEDEAGRGTGETRPVDAAGASGGSLGTEPEMVSRVPDGMPLFRPAEEEDEFFPGDDQLCGFLDTIDSAAKPPVKQSPVIEQEQEQEEEDEFAEEEALLREADLADASLQKSSSLPMAGSGPSAPREEPGHDWDDLYQ
The following text describes a protein:
Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases (Probable). They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (Probable). Involved in the oxidative metabolism of thiabendazole (TBZ). Catalyzes the conversion of TBZ to its hydroxylated form.
Miscellaneous:
MISCELLANEOUS: Thiabendazole (TBZ) is used as a broad-spectrum anthelmintic to treat parasitic nematode infections in humans and veterinary animals.
Sequence:
MILILLFLTAITVITVRLYRKVLRFPPGPFPLPLIGNAHQIAYQAWRRGGILPALDYYRKKYGNAYTLWLGPKASVSITDFETSQEVFVKQGKKCYNRQLAPILEHVTGGVGLLIANGENWAEMRRFTLLTFRQMGVGTNIMEKRIMDELNGRCLEIDAQIARNDRAIVDVKFFDLTVGSVINSFLIGKRFEDEEEFLKIKKLFDESSETFNIFDLNVPVWFLKTFLPSRFKLTWDSRHQIMDHVMKGVEERIRDIESGAYKIDPKKPNDVVDAFLSKMKKEEEIAGGQHPYYNLKSLKLVLHDLWLAGQGTTATTLYVGFMKLVNHPGIIQNIQKELLDITENGARDLTLKDRPNTPYLNATIAEIQRHASILNVNFWRINHETIHFNDYQVDPGTMIAAQVGVLHVNEELFDNPKDFNVEKYLKNPKLLQQVIPFGIGKRSCVGEQIAKSELYLVFGNILLRYNVKKHGSTPTNEDVYPYSSAKLPDVSGKLEFVKL