lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Lipid transfer protein that, together with LTPG1, binds to lipids and functions as a component of the cuticular lipid export machinery that performs extensive export of intracellular lipids (e.g. C29 alkane) from epidermal cells to the surface to build the cuticular wax layer and silique walls. Contributes to pre-invasive defense against some non-host powdery mildew pathogens by preventing the penetration of the epidermal cell wall by the fungal agents (e.g. Blumeria graminis f. sp. hordei (Bgh)). Involved in seed and ovule maturation and development, probably by regulating the fatty acids homeostasis during suberin and sporopollenin biosynthesis or deposition.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Note=Targeted to the plasma membrane via the vesicular trafficking system.
Sequence:
MSNVVVIAVVLIVASLTGHVSAQMDMSPSSGPSGAPDCMANLMNMTGCLSYVTVGEGGGAAKPDKTCCPALAGLVESSPQCLCYLLSGDMAAQLGIKIDKAKALKLPGVCGVITPDPSLCSLFGIPVGAPVAMGDEGASPAYAPGSMSGAESPGGFGSGPSASRGSDAPSSAPYSLFLNLIIFPLAFAFYIFC
The following text describes a protein:
Function:
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Subcellular Localization:
Cell membrane, sarcolemma; Single-pass membrane protein. Cytoplasm, cytoskeleton.
Sequence:
MEVKTSSYFIGIFLAVLHPHLTQGLTVFSGVNFQHPILRTDYFDEYTLDSTDPIIFRPSLVSKPSLPSWLKFIQPAESSDGYLYGTPQGSNIGQFNLEIIGLNSRTYESARKLVPMTVEENTGSSSKYQADFFITNLNLADILDTEIQDDFRSGVNAFWGQGSQVTIQSLTSAQDLGLRVPLNPQPDQKYGVRITIGARQESETLAKVISDAVGPCQQDSTYTPPDINGFFQPAFTIDWCNVSMMEVSPTQLQNESTPVFLGGMYEPPIMQVEDTDRFLEFLLLVVVPCAIMFCSILVLGYLMCCGRSGRKEVASTSELQLTHHRTLRQACRDLRTMSNRRDGTASVATLTPIGTPTVGSQRSHSRSRGYDEYPWASSTPQVNHRGMATPPPYRTPPHPHKHRETSFSNQASDKRRLSEPSNARGGESPSMRPVPPFMGSTTSDRVRPRHV
The following text describes a protein:
Function:
Part of the adaptive DNA-repair response to alkylating agents. Could prevent alkylation damage by protecting DNA and destroying alkylating agents that have yet to reach their DNA target. Binds to double-stranded DNA with a preference for a DNA region that includes its own promoter. Shows weak isovaleryl-CoA dehydrogenase activity in vitro.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal region contains FAD-dependent dehydrogenase activity and the C-terminal region contains DNA-binding activity.
Sequence:
MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLASIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALCTNRVHNLAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPAPFQDWTTPLLSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFSVPQSDAHLVLAQTAGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDAIGWLLGLEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQPLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPFVAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLSEAFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLLGCGAQMLKYASPPMAQAWCQVMLDTRGGVRLSEQIQNDLLLRATGGVCV
The following text describes a protein:
Function:
Cleaves the 2'-5' phosphodiester linkage at the branch point of excised lariat intron RNA and converts them into linear molecules that can be subsequently degraded, thereby facilitating ribonucleotide turnover.
Subcellular Localization:
Cytoplasm, perinuclear region. Note=In trophozoites, appears to localize to the cytoplasmic side of the nucleus concentrating on the basal region.
Sequence:
MATEQIQHIAIVGCVHGKYREMYRQLSEYEKSTGKEISFVICTGDMQTLRYEADLVYLKVPPKYKQMGDFHLYYEGKEKAPYLTLFIGGNHESSNVLLHLYNGGFVCFNMYYLGVCSCININGLRIVGVSGIYKSFDEKKPYTYPPSPNDVVSLFHTRNYVIQMLSNLSQSSQIDISLSHDWPQGIVMKGNYKQLYRFQPGFKKDGASLGSPINKVILNTLKPKYWISGHMHCEYHAEEGPTHFIALGKIGYKNAISYLDLPLKQKTDLEYDKDWVCNLIMTWPAFSNKAQFPDLSYSISELLSKRTKELDKKIIELWEKYIGLKIIYDSDTFDIQFTSRRFYIEKIYNELNIN
The following text describes a protein:
Function:
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
Subcellular Localization:
Nucleus.
Sequence:
MTDASKYKKLTPIDHVLLRPEMYVGSIETQPTPMYIFDPEKGRMVWETMRVNQGLLKIVDEILLNAADNINNSKGSVRQTYINIHISDTGEITVENDGAGLPIVRSREHKMYIPEMVFGHLLTSSNYNNDSTSTTAGRHGYGAKLTNILSTKFSVVCRTDGREFHMSWTDHMRMATAPRVNRVDPKEKNVTRVKFMPDYAHFGFPSASISLDMKRVLHKRVMDLAAMFSKIEVRLNNVPFGFRTFTDYAGLYSLPGLDGSMPPEPFVYTSPNGSVAYVPQLTQSPKRIVSVVNGVVTYNGGTHCNAAMDILDACLDSLSKNFKKNGKVVDTNRVQRHFTVLVFLVQAQPKFDSQSKARLVSTVTMPRVPKNTLEKYLERMPFLEAHVNSMDDQLTNELNKEIGAGRRLSSKTLISSITKLVDATSSRPDGRNIRTLIITEGDSAKALALNSLSSEQKKYCGVFPLRGKLLNVRNKNLKRLKTCKELQDLFLSLGLELGKEYRSPAELRYQRLLVMTDQDADGSHIKGLVINAFESLWPKLLQNNPGYISLFSTPIVKIKVSGKSKEAIAFHSFRDFHRWQRAHPSARYTAKYYKGLGTSTTAEGKEYFADMEKNVMQLTVDARDHQLLDSVFDAAEVEWRKEWMTKANAFQGEVDIDRSKKTLTIPEFVHKEMVHFALVGNARAIPHCVDGLKPSQRKILWAMLRRHNSEASKVAQLSGYISEASAFHHGEASLQETIVKMAQNFTGGNNINLLVPEGQFGSRQQLGSDHAAPRYIFTKLSRFARLLFPEEDDPLLDYMDEEGTFVEPHHYVPILPMLLCNGAVGIGFGFATTIPSFHPLDVSAAVRAMINGESAKQVVRNLVPWAVGFQGTVRRGPDNEFIAVGKYTAHPNGRFHISEIPWMTSIEAFRLHISSLASADVVQRIADYSGANHIDIDLIVRDGSLTTWAECETDLALAQRIYINGTVFSPAGTLSPIDSDLSPVLQWHYDRRLDLYKRRRTRKIGLMEMDLARLQSTRKFVEHFRQGQIDFLNATDDTLHKTCVKLGLVRVDESFDYILKKPITFFTRTSTEKLQADIAKTQAQIEELKRTTPVKMWLTELDKFDKTFQEYERVLINSIQKEQRSSSITGGVELPALRQPLLLLEASVKGATAYRVHACQYEKPPPSKRRPGESFGGARSSDSAVRGVGKRLVGSRAVFKKKKPMGRKNNVKVSLSTRVAQFAGAQLGRLLPHILV
The following text describes a protein:
Function:
Catalyzes the production of cysteine from cystathionine in the reverse transsulfuration pathway for the biosynthesis of sulfur-containing amino acids cysteine and methionine. In this pathway, homocysteine sulfur is converted to cysteine sulfur (Probable). Also has cystathionine beta-lyase and cystathionine gamma-synthase activities in vitro. Cystathionine beta-lyase may be physiological, while cystathionine gamma-synthase activity is not, as the required substrate O-succinyl-L-homoserine(OSH) does not occur naturally in S.cerevisiae.
Miscellaneous:
MISCELLANEOUS: Present with 38300 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MTLQESDKFATKAIHAGEHVDVHGSVIEPISLSTTFKQSSPANPIGTYEYSRSQNPNRENLERAVAALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVETSFTNDLLNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVILVVDNTFLSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPSPFDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQHRDALGGGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPKEAREASGVFDDLVRISVGIEDTDDLLEDIKQALKQATN
The following text describes a protein:
Function:
Acts as a component of a SCF E3 ubiquitin ligase complexes.
Subcellular Localization:
Nucleus.
Sequence:
MHFSADVSIPVPSEFGTFSRLRTMQFVGTERPWLNLYGNRIRPVAPFGSVSSTPFTDPSLIHRCLPDELLLEVFSRMNPYTLGRAACVCRKWRYAIRNPNLWRNACLKIWQASGVETNYRIVHSLYDGSWRKMWVWRPRIRNDGLYVSRNTYIRTGVAEWKVTNPVHVVCYYRYLRFYPSGKFLYKISSQKVKDVVKCMNRASKADCVFKGDYILTEDQVETALLYPGLRYTLLRMRLRLRGTTLGANNRLDVLKLVTTGVNESEVRNHGDDMLGIVEGWEEDETHDPDVPAISHGRGLTPFVFVSFEEAETSVLNLPVDKMDYFVPG
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Sequence:
MTVNVLIVGAGAVGAFYGSRIAQVQDTQVSVICRSNYQAVVANGFNVTSPKFGEYKFIPHQTFSNPQEARKSDKYWDFIVVSTKALPDVCDDSKILEGLVKTGHTSVVLIQNGLGVEEPYSKRFPECTILSAVTIVSAEQSSPGIIKHNRWTRISIGPYLPGVTESTKLNDEEKIAVNRNSTFVKLLQAGGISDAQEYSHWKLQMVRWHKIAINASMNPSAVLSAGSTNNEMSLDPELYIHLKGVMDEVLETAPKILGTKLPEEFATSEQLLKSTQKNTSGSKPSMLLDWEQGKTMELEVIMGNPIRIARSHGLEMPRLQTLYALLRKAQENEMKSRAGSKL
The following text describes a protein:
Function:
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MTGKEENKQQQHVNFPWKRLVAGAVAGTADVWACHPLDRIKTQLQNNPGKSIVGTFGDIVSKGKGFTGGVNALYEGILPMTAEAIFKVGIRYFAFSWFTEQYKTTVYKGETLNKKQQFGANLLGGAFAGTIESFVVVIPCELLKVRHMTQEHNKSFGTVFRDVLREEGFQGLYKGGSATLLRQITNHMIRFPTFYAISDYLKGGDHSVHLPVWQNLSAGAIAGTASTLFNNPLDTIKTRMQKQGQNQTTMQVVRGIYQETGVKGYWAGVIPRILRVAPGQAITWAVVELVMGILEPSSKKH
The following text describes a protein:
Function:
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
Sequence:
MNEELTQRCEEIRKNLIEVVSKNGGHLGSNLGVVELTVCLDEIFDFKEDIVLFDVGHQAYIYKILTDRAERFDSIRTRKGLSPFLDPNESSYDHFISGHAGTALPAAVGFAIANPDKKVIVVVGDASISNGHSLEALNYIGYKKLENILIIVNDNEMSIGENVGFISKFLKKVISSGKYQNFREDVKSFINRIKADRVKRTLERLERSIKGYVTPFYALESLGFRFFNVFEGNNIEKLLPMLKKIKDLKGPTILLVKTEKGKGYCFAEEDKEKFHGIAPFNIETGNTYKSLVSYSEVFGNKILELGKEDENIYTLSAAMIKGTGLHKFSEEFPERCIDTGIAEGFTVTLAAGLAKSGKKPYVCIYSTFIQRAISQLIHDVSIQNLPVRFIIDRSGIVGEDGKTHNGIYDLSFFLSIQNFTVLCPTTAKELGQALEISKNFNLGPLVIRIPRDSIFDIENEEPLEIGRWKVIKKGSKNLFIATGTMLKIILEIYDKLQNRGIYCTIISAASVKPLDENYLLNYIKEYDNIFVLEENYVKNSFGTAILEFFNDNGIQKPLHRIALKSAIIPHGKREELLKEERLKGESLIERIEELIYGRKK
The following text describes a protein:
Function:
Transcription coactivator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences. May regulate leaf size, length of stem internodes, and seed size by promoting cell expansion (Probable). Transcription coactivator that plays a role in the regulation of grain size. Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable). Component of the miRNA396c-GRF4-GIF1 regulatory module that plays an important role in grain size determination.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing GIF1 exhibit increased size of multiple organs, such as leaves, stems, panicles and grains; MISCELLANEOUS: 'Makiba' means 'pasture land' in Japanese.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Localizes predominantly in the nucleus.
Sequence:
MQQQHLMQMNQGMMGGYASPTTVTTDLIQQYLDENKQLILAILDNQNNGKVEECARNQAKLQHNLMYLAAIADSQPPQTAAMSQYPSNLMMQSGARYMPQQSAQMMAPQSLMAARSSMMYAQPALSPLQQQQQQQAAAAHGQLGMGSGGTTSGFSILHGEASMGGGGGGGGAGNSMMNAGVFSDFGRGGGGGGKEGSTSLSVDVRGANSGAQSGDGEYLKGTEEEGS
The following text describes a protein:
Function:
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. Acts as a regulator of mitochondrial fission by modulating the phosphorylation of DNM1L at 'Ser-616' and 'Ser-637' which activate and inactivate the GTPase activity of DNM1L respectively.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Translocated into the nucleus upon activation by IFN-alpha/beta.
Sequence:
MAQWEMLQNLDSPFQDQLHQLYSESLLPVDVRQYLAVWIEDQNWQEAALGNDDSKANMLFFHFLDQLNYDCGRCGQDPECLLLQHNLRKFYRDIQAIPQGPTRLAEMIFNLLLEEKRILIQAQRAQLEQQEPALEAPGENQQHEIESRILELRAMMEKLVKSISQLKDQQDIFCFRYKIKASAKTHSLDPHRTRQEQVLQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKVQQQKACIGAPMDGELEQLEKWFTAEAKLLFHLRQLLKELKGLSSVVKYDEDLLFKGVDLLKAQVTELLQRLLHRAFIVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTAEVSIDRNPPKSQGFRKFNILTSNRKTLTPEKGQSQGLIWDFGYLTLMEQRSGGAGKGNNKGPLGVTEELHIISFTVKYTYQGLKQELTTDTLPVVIISNMNQLSIAWASILWFNLLSSDPQNQQFFSSPPKAPWNLLGPALSWQFSSHVGQGLNSDQLGMLRDKLFGQNSSTEGLSLSWVDFIKRESPPGKLPFWTWLDKILDLVHDHLKDLWKDGHIMGFVSRSEERRLLKKTISGTFLLRFSETLEGGITCSWVEHQDDDKVLIYSLQPFTKEVLQSLPLTKIISQYQLLTEENIPENPLRFLYPRIPRDEAFGCYNQEKANLQERKKYLKHKLIVVSNRQVDELQQPPELKLEPDLESLELDLGLAPGPEPGVGLDLEPLLEAGLDLGPELEPMLQSTLEPVLEPILDEVLQGVPEPNLGPELKLEPILEPVSQPVPEPDLPHDLRHLNTDEMQIFRNSMRIEEIMPNGDPLLASQNTNVDEACVFHRSHFYTDGPLIPSDY
The following text describes a protein:
Function:
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
Sequence:
MADLDQGSAELGVPSPIVAVARHEHEAVQSTNDDATLAKWCGEPHGAADVQKTPTTCGSHPAVLSCAVRRGYWADPYVSLFAAGMKTHPCSPLIHRGYFVRVQAVERTVRSFIAQHGAQAQILSLGAGFDTLFFRLMNDNVTLRRYVEVDFPAVVEKKRQICSSKAPLRSVLSDLASPSEVASLLDRGRLDPGLPLLVISECVLVYMAPEAVANLIQWTSSTFDLAYWLDYEPVCGVNQPAWADFLFYLMNRDMDGSSVSNR
The following text describes a protein:
Function:
Antimicrobial protein which is essential for the homeostatic regulation of sleep. Promotes sleep following sleep deprivation or bacterial infection and increases survival following bacterial infection. Likely to promote survival to bacterial infection in two ways; by contributing to the innate immune response and by promoting sleep during sickness to aid recovery.
Miscellaneous:
MISCELLANEOUS: The name 'nemuri' means sleep in Japanese.
Subcellular Localization:
Secreted.
Sequence:
MSAKYTLIFALAALCCLVFSTEAAAQRSRVLSSRRGSELVEKTSDNKEDSELAAQEQDLERQEQEEQNDRLEGRSDDVAEGSDNKEDKETATNNKDTIVKPNKDDARARRIVRAGRRRGGRRGGRRGGRRSARKSVRRGGRRGGRRRGGRRGRGGARRRTSVKRRSGKGNKA
The following text describes a protein:
Function:
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity). Required for growth at alkaline pH.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNLWRHSPEELAAYNSCHPMKLGSGVLIQLPLYDNSAVYAEDITFRSFCCERVPVYVSTVLRNSSPYRYLDEVINDWQKFIQVSDYVGGSAEYAIYAVILSITSNFVITVFLTVICCINISGRAYKRILQLLRIASLLASLNLTIFITKVLRRLEKEHNVYGVVRAHSIMHIFSDDMTFVVLDFLATLMFQFCQVGIVIRLFQRAQEKRIIFFIGVILTITANILWVIPPFANHTTKHRNDWQILRPFVYLFRIAIATSYASIVIYHIWQKKKLWFKFNQMGLLTLLTILVVLLLPGFFLADVSNLWISELGEVFNTTCYVTSTVITWEWLDRLNVLERKEEAQSILGRPIFEEEQQDYRFAKYALRVQNALTRRESQDASTDRHDTSSNSEVCDLQTISRYDPEDQISVGRSIDRMHFNDRGTYKDVALKKLGYARDKILYFTDQIVQKSVGHNNSSSSKNEKTKQRKAMVRKRLGLDKPGIYIYSTKDVVFNSDEDDDENAEDEDDDEYEVGSEGNNNSSATFTSDHIGHI
The following text describes a protein:
Function:
May play an important function during spermatogenesis and/or in the male genital tract.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MLRLCLPTRAGYVRNFSNDKPRKPETHYEVLNIRNDCSTREVRNAFVQLSKLYHPDVKSNAACPERTARFVQISEAYKTLIKPERRRDYDDSLLWQPSRSDRSPVGETVNPGQAWDVRPNYDPNPGPYYGIRGLKRVSNWQVAVVLMALGFVGALFGFTSVRSSFKLSRQIQDEISAEANSHHAAVVADAQKYGNEEQVRRMVDRMSRSPFNQSSAK
The following text describes a protein:
Function:
Mitochondrial protein that is involved in citrinin resistance.
Subcellular Localization:
Mitochondrion.
Sequence:
MQSISNCPIGLVSKNTINSASTIAEWVACPWKYINVVGSGRYVSNKPDKITRYDLLKAAQEAEMQELLTRNDMKGRHKRNKKSKIALETIAEENSSTESLF
The following text describes a protein:
Function:
Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Domain:
Consists mainly of an outer membrane-spanning beta-barrel formed by beta-strands both N- and C-terminus residing in the periplasm.
Sequence:
MQFLKKNKPLFGIVTLALACATAQAQPTQGGVSLHYGIGDHYQRVTLNYETPTLWSHQFGGNWGRLDLTPELGASYWWADGSRSPGHVWQASAIPMFRWWTGERFYIEAGIGATVFSSTSFADKRIGSAFQFGDHIGLGFLLTPSNRIGLRYSHFSNAGIKEPNPGLDIVQLTYTYQF
The following text describes a protein:
Function:
Aspartic protease. Appears to act as negative regulator of constitutive exocytosis. May act at the level of secretory vesicle docking and fusion as a competitive inhibitor of SNARE assembly. Acts as a linker between the 19S proteasome and polyubiquitinated proteins like the HO endonuclease and UFO1 via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control.
Miscellaneous:
MISCELLANEOUS: Present with 6510 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MDLTISNELTGEIYGPIEVSEDMALTDLIALLQADCGFDKTKHDLYYNMDILDSNRTQSLKELGLKTDDLLLIRGKISNSIQTDAATLSDEAFIEQFRQELLNNQMLRSQLILQIPGLNDLVNDPLLFRERLGPLILQRRYGGYNTAMNPFGIPQDEYTRLMANPDDPDNKKRIAELLDQQAIDEQLRNAIEYTPEMFTQVPMLYINIEINNYPVKAFVDTGAQTTIMSTRLAKKTGLSRMIDKRFIGEARGVGTGKIIGRIHQAQVKIETQYIPCSFTVLDTDIDVLIGLDMLKRHLACVDLKENVLRIAEVETSFLSEAEIPKSFQEGLPAPTSVTTSSDKPLTPTKTSSTLPPQPGAVPALAPRTGMGPTPTGRSTAGATTATGRTFPEQTIKQLMDLGFPRDAVVKALKQTNGNAEFAASLLFQ
The following text describes a protein:
Function:
Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAEHDYHEDYGFSSFNDSSQEEHQDFLQFSKVFLPCMYLVVFVCGLVGNSLVLVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWVFGQVMCKSLLGIYTINFYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLPQIIYGNVFNLDKLICGYHDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVFLLTQMPFNLMKFIRSTHWEYYAMTSFHYTIMVTEAIAYLRACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL
The following text describes a protein:
Function:
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
Sequence:
MAPSRGLALLRARLGLSARSSASCIGVGGVRNFASFTDTLSDPKNKLQSYISTSNDPYLNLAIEDHILRKSPPHSTVLFMYVNRPCVVIGRNQNPWTEVNLGILHAARNGNAQDMETEPPGIGAIDLVRRRSGGGTVFHDEGNLNWSVTCPRSDFTRDRHAEMVVRALRKLNVDRARVNERHDIVLDQGHEKLPSDPEDTHRTPYTVPDGALPKPLKVSGSAYKLTRLRALHHATTLLSSPNLHIIPRYLRSPAKRHIQAKGVESVSSPVGNIGLDVKPFQQRLQEEFANMYAAVGDADVVATVGTDHLKVPDIKKGYDELRTEDWMWSQTPQFDLLLDTPDDIGISMNVHHGIIKSLELKHSRLSPRTQDQLRKALVERKLQDIREWSTFLQTQLGKLEDRTSGIASRLDELMPVPRLADS
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum. Nucleus, nucleolus.
Sequence:
MAADKPQPGGGGGGGGGGGGGGGRGPTREENKENERPVAANKPKRSAALGDSLGLEILQIIKDSQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEELLSDSRYLLLILMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYMAYLSGMLRFEHQDWELAMEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQTAISELIQMRLRSGGTEGLLAEKLEALISQTRAKQAATMSEVEWRGRTVPVKIDRVRIFLLGLADSEAAIAQAENEETKERLFESVLSECRDTIQAVREELKPDQKQREHLPEVESGKVSNLQYLHSYLTFIKLSTAIRRNESMAKGLQQALLQHQPEDESRRSPRPQDLIRLYDIILQNLLELPQLPGLEEDKAFQKEVGLKALVYKAYRCFFIAQSYVLVKKWSEALVLYDRVLKYAREMQAQAGDSDTSLKELPDVQELISQVNAEKYSLQAAAILPLVERFETFSLDPSLVSKQANLVHFPPGFQPIPCKPLFFDLALNHVAFPPLEDKVEQKPKSGLTGYIKGIFGFRS
The following text describes a protein:
Function:
Component of the gamma-tubulin complex that is required for the regulation of both interphase microtubule organization and nucleation, and mitotic bipolar spindles. Required for correct septation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Localizes to the SPB and also to the equatorial MTOC.
Sequence:
MTMSRADQILQHLLRELIHNDSLVASEWLKHSKKIIQNVPSSTLVFHEMIEHIKGICDKMGIQGREDLEMPLRNACEVLNRQTVSVKQSILHAQILKLFLELSKPPSDIHVPQIPVYKDCNKNEQEAIIQLLTSCEGDHWLMPDWSSMPDDETITEDSEEETFNGNANEITIPANIHIPIIEESDNASNNKLCTLFKKSKQPNLDFLQIKPFMFWDSSLNETVRISERSIIRDSIYMLIGYPSFFFLKNGSKIETRLSLLPKLHHMSEEILRSIMTELADYGSNLEFFRQKLTSPSDSFFKSDDQSTKNEPFLSVVFIYPQIKPHLLSCLKNTHQELIKLETEVYNATKNCTLFQFFQHVKKFVDPLLCFRFAYEKSATNMWDFVKTLEFIYSTRNYSSQMFKLYKASAIAMLLWMVNQASQITSSMTIARPLYNILILCKDFPNNFLEKDNIALQLGSIVFDQSPTLNNLLVEMEILIRSKILKLGKSLDLSFDFQSLMGEFENLIKQQEEAKKSLWSKRFSRFYYGHYVFVNTCHNFFLTLYQSFTEVDENSIFNGVFETLNNDVDDESVIGEKEKLILKQKQKCLSEFFVDDIKKLLNEELLNCQKQELPDVMENTYQISTVSGIKNDPLFTLDQTCNIIAKLADNLIHPSVPIGSSAYRCRRNLADLLFLIMP
The following text describes a protein:
Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MARLLDLGNIDLWRSEEMQLVQLMIPADNAHDTVEALGEIGLLQFKDLNVDKSAFQRTYANQVRRCDEMARKLRFFKEQIEKAHIPVPSRSLLDNRASVTLDELESLLEAAEREAVEMNANHDRLQRAHSELSELSLLLDCAGKFFDSARRAAVGAGTVAGGLGAVGSAGGVGSGLGGSAADVSSPLLGGGSGGGGLSAMEAPTQYEPKIGRLGSIAGLIARERLPGFERLLFRATRGNNYFRSMSVGKVMDPATGESVEKAVFVVFFAGERARTKIGKICEAFGANRYPLPEEPNRQRAMAAEVGGRLTEMKTTLEIGDLQRTRLLQKVAADLDVWTSLVRREKAVYHTLNKCSVDVTRKVLVAEAWVPSSARPRVQEALRAVASSAAQVGSILQPLVSHENPPTYFKTNKFTNSFQAIVEAYGVARYREVNPAVFTIVTFPFLFAVMFGDLGHGALMTVFGVWLLINESKFAKQQLDDMFGMLYGGRYVIFLMGLFSLYMGLIYNEFFSMPMSLFGDSAFTCFVNGVKDSSIDRRDCSHAGGEVRMDRTRGPYWFGVDPIWHGTKTELPFLNSMKMKMSILLGVAHMNLGIIMSLLNNNYFRDRLSTICEFVPQMIFLNSLFGYLSALIVGKWLTGAVTDLYHVMIYMFLQPGNVDEAGFLFTGQAGLQVFLLLVAFAAVPWMLLPKPLVLKKRAEAAARVRGEYHRLNEDTETGRQHAGSTDTATHGGAAGGGGHGGGGGHGGHGEQFEFGEVIVHQMIHTIEFMIHTIEFVLGAVSNTASYLRLWALSLAHSQLSAVFYDRVLMAAVESGSPAAMVVGFFVFACATLGVLMVMESLSAFLHALRLHWVEFQNKFYRGDGYSFAPFSFHANQDEHAAS
The following text describes a protein:
Function:
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but also occur in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Subcellular Localization:
Mitochondrion. Nucleus.
Sequence:
MLRNWRLLVRSFATNSSEEIAPKVDVSFLRPRHRIIAAGGMPPVQFDSERERASRRERFGKYGLKSGVPVEELFPTAEEIEEEEAIGLFREFNNAKKEYKELQKKKRESELARIAELEKNLKKYPATLAKYEASLVKQEQEKDEKEVALEKRIRDIQEYFGYWMDPKDPRFEVMLQQKEAEEKKAVKMAKRDEIQKKRFAENVQG
The following text describes a protein:
Function:
Initiates the restart of stalled replication forks, which reloads the replicative helicase on sites other than the origin of replication. Recognizes and binds to abandoned replication forks and remodels them to uncover a helicase loading site. Promotes assembly of the primosome at these replication forks.
Sequence:
MKKYVDVILPLPLPKYFTYSLPDECAEEVEIGCRVIVPFGRKKFYTAIVRNVHYCAPTEYEVKDISALLDASPILLSTQFKFWEWLADYYLCTQGDVYKAALPSGLKLESETIVEYNPDFEADAPLSEREQRILDLLSVDSQQCVTKLEKESGMKNILTVIKSLLDKEAIFVKEELRRTYKPKTEARVRLAGSADEKRLHILFDILSRAPKQLALLMKYVECSGILGRETPKEVSKKELLQRAGVSPSILNGLVEKKIFEIYFHEVGRLNQEMKEVVELNALNEFQQRAHDEIVQSFQEKNVCLLHGVTSSGKTEVYIHLIEETIRQGKQVLYLLPEIALTTQITERLQRVFGSRLGIYHSKFPDAERVEIWRKQLGDKGYDIILGVRSSVFLPFRDLGLVIVDEEHENTYKQQDPAPRYHARNAAIVLAAMYGAKTLLGTATPSIETWQNARNGKYGFVQLKERYKEIQLPEIIPVDIKELHRKRRMVGQFSPLLIQYMKEALEQKEQVILFQNRRGFAPMIECRTCGWVPKCKNCDVSLTYHKGINQLTCHYCGYTYQLPKFCPACEGTELVNRGFGTEKIEDDIKVLFPEAAVARMDLDTTRTRAAYEKIIADFEQGKTDILIGTQMVSKGLDFDHVSIVGILNADTMLNYPDFRSYERAFQLMAQVAGRAGRKNKRGRVVLQTKSIDHPIIHQVIGNNYEEMVDGQLAERQMFHYPPYYRLVYVYLKNHNEALLDQMAAVMAEKLRTVFGNRVLGPDKPPVARIQTLFIKKIVLKIEQNAPMGRARELLQRIQKEMLEDERYKSLIVYYDVDPM