lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of timm9/timm10 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By similarity).
Sequence:
MDDVEMKVMEMKMISKMFQGILDACSAKCISKYNEGDLNVGESVCAERCVQKWMETFKKVQSKMSGTQPGQEVPQEAPAAAPEKKGWF
The following text describes a protein:
Function:
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Rapidly and constitutively internalized to the trans-Golgi network at steady state.
Sequence:
MDTSRVRMLLSLLALLQLVAAGSPPRPDTMPRGCPSYCHCELDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLPASLLHRLRFLEELRLAGNALTHIPKGAFAGLHSLKVLMLQNNQLRQVPEEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTDVPVQAFRSLSALQAMTLALNKIHHIADHAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIKTLSNLKELGFHSNNIRSIPERAFVGNPSLITIHFYDNPIQFVGISAFQHLPELRTLTLNGASQITEFPDLTGTATLESLTLTGAKISSLPQTVCDQLPNLQVLDLSYNLLEDLPSLSGCQKLQKIDLRHNEIYEIKGGTFQQLFNLRSLNLARNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPVTGLHGLTHLKLTGNRALQSLIPSANFPELKIIEMPYAYQCCAFGGCENVYKIPNQWNKDDSSSVDDLRKKDAGLFQVQDERDLEDFLLDFEEDLKVLHSVQCSPPPGPFKPCEHLFGSWLIRIGVWTTAVLALSCNALVAFTVFRTPLYISSIKLLIGVIAVVDILMGVSSAILAVVDTFTFGSFAQHGAWWEGGIGCQIVGFLSIFASESSVFLLTLAALERGFSVKCSSKFEMKAPLSSLKAIILLCVLLALTIATVPLLGGSEYNASPLCLPLPFGEPSTTGYMVALVLLNSLCFLIMTIAYTRLYCSLEKGELENLWDCSMVKHTALLLFTNCILYCPVAFLSFSSLLNLTFISPEVIKFILLVIVPLPACLNPLLYIVFNPHFKEDMGSLGKQTRFWTRAKHPSLLSINSDDVEKRSCDSTQALVSFTHASIAYDLPSDSGSSPAYPMTESCHLSSVAFVPCL
The following text describes a protein:
Function:
Reductive dechlorination of ortho-chlorophenols. Dechlorinates in the ortho position with respect to the hydroxyl group.
Subcellular Localization:
Secreted. Secreted, cell wall. Cell membrane. Note=Associated with the cell membrane. Probably binds to peptidoglycans of the cell membrane and cell wall.
Domain:
LysM domains are thought to be involved in peptidoglycan binding.
Sequence:
MKKTLGIILSISLAFSVLALPIFAAVDTTTSATVEAATPAAPATPAATAPAAAPSVDTSKIAAGTYYTVVSGDFFWQIAAKHGLTIDALAKLNPQIKNVNLIFPGQKILVKAEEAAAASTSTSTAAVAPAAKKLYQGIGMAANYRDNTARQKDHDNLNITTVAALFDDAGKIVKLQFDVVEILPDMFPGWMDPEAADKSFYKDAQANGFNWETKKEEGDAYGMKASAVSGKEWWEQMNFYEEYFKGKTVAEVQDWFAKYCDANGRPYKMAYPEKLTDADKAKVATFTEAEKKMLVDVTTGATMSLQDPHSRFIDALVKAYEVRKEVK
The following text describes a protein:
Function:
Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. Stimulates the expression of Onecut3 in the developing endoderm.
Subcellular Localization:
Nucleus.
Sequence:
MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVGHRGSHLPPAHPRSMGMASLLDGGSGGSDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSGSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEGGSNSGSSSSSSSTCTKA
The following text describes a protein:
Function:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Sequence:
MEVYNVPGQGLADMYLIQGSEPIPQFISQFEPLESMYNEGAPDYFVDQGLYYPPTTNYGYICTGFESTGDWEDHQRIFGLDGQDLQYTGVTNENLPYVYYNPSYGYGQSPYNPYNPYIPGAMIGLDGSIVAPQQYYAIPSYENPISSPSYVPVVLQSRPESRANGIGDSFVDNAVSVSKVDGLVSRYNLPPNTPNSSLARLGDNSSRRNSSARMSEGGGANTGSVKQHWPNVTSVNFTNRASSQISLARDPQGTENALRGKASSASSQSKSAFTSAKGLSGFESSNHAQASVHRVKPNALYDRVTDAERASPDALREQNGGPLIEQNRGSRTNKLKNELVVRAYTTRAGNPDAQGNITIFKDQYNKIDFPVDYANAKFFVIKSYSEDDVHKSIKYNVWSSTPNGNKKLTTAYQDAHRTTLGDLRGCPIFLFFSVNASGQFCGVAEMTGPVDFHRDMDFWQQDKWSGSFPVKWHIIKDLPNSNFRHIILENNENKPVTNSRDTQEICYEKGLEMLRIYKSHTLKTSLLDDFMYYENRQRILQEERTRLLRKSYENQYLVPQLDPPRKLQYVHDFPYTGDVNGTNNDADNLTIVNKNKVSEDSETDSSVTKKHCASTEQVSSSDSSTNKLTSVSESGADGVPKTVDELKMSSLTINAEKTEPECPLPSVAVSSTTKKEQVKVVTIGSMAVKVTGNESCGFLTVGTIPLDPRALKGD
The following text describes a protein:
Function:
Necessary for the bidirectional replication of DNA. It interacts with the ori (origin of replication) region of the genome during the initiation of replication.
Sequence:
MTNTAKILNFGRGNFAGQERNVADLDDGYARLSNMLLEAYSGADLTKRQFKVLLAILRKTYGWNKPMDRITDSQLSEITKLPVKRCNEAKLELVRMNIIKQQGGMFGPNKNISEWCIPQNEGKSPKTRDKTSLKLGDCYPSKQGDTKDTITKEKRKDYSSENSGESSDQPENDLSVVKPDAAIQSGSKWGTAEDLTAAEWMFDMVKTIAPSARKPNFAGWANDIRLMRERDGRNHRDMCVLFRWACQDNFWSGNVLSPAKLRDKWTQLEINRNKQQAGVTASKPKLDLTNTDWIYGVDLKTSPHRWLTLTVSRCVGSPTTCRNSTTKSRRYSR
The following text describes a protein:
Function:
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability.
Subcellular Localization:
Nucleus. Note=Isoform 2 is not localized to the nucleus.
Domain:
The NAB conserved domain 1 (NCD1) interacts with EGR1 inhibitory domain and mediates multimerization; The NAB conserved domain 2 (NCD2) is necessary for transcriptional repression.
Sequence:
MHRAPSPTAEQPPGRGDNTRRTPQPRFKASAPAMALPRTLGELQLYRVLQRANLLSYYETFIQQGGDDVQQLCEAGEEEFLEIMALVGMATKPLHVRRLQKALREWATNPGLFSQPVPAVPVSSIPLFKISETAGTRKGSMSNGHGSPGEKAGSARSFSPKSPLELGEKLSPLPGGPGAGDPRIWPGQSTPESDVGAGGEEEAGSPPFSPPAGGGVSEGPGVGGVAAGGAGGGPDRLEPEMVRMVVESVERIFRSFPRGDTGEIASLLKLNKKLARSVGHIFEMDDHDAQKEEEIRKYSVIYGRLDSKRREGKQLSLHELTINEAAAQFCMRDNTLLLRRVELFSLSRQVARESTYLSSLKGSRLHSEELGGPPLKKLKQEVGEQSHNEIQQPPPGPESYAPPYRPSLEEDSASLSGESLDGHLQAVGSCPRLTPPPADLPLALPAHGLWSRHILQQTLMDEGLRLARLVSHDRVGRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPALVEGRRSSVKVEAEASRQ
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation.
Subcellular Localization:
Cytoplasm. Mitochondrion matrix.
Sequence:
MFRCGLLVLSPACFRGRIPSLLELASREIKDVLYIDIYGSKNESLGRFYGFLADVYGVHSCGSLDVRVLQPEQKQCETRKLSHVPEVAFLRDFSTDVGLDLQTLKRHVQRRFPTLEAERVKIIEPIIKEREEKHWPEPKTYAETVLGGTFDHIHAGHRLLLSVSCLLCTKRITVGLADGPLLSKKVLKELMQTFDERKKIVEQFIEDISPDLHHNVVPITDPIGPSGTDPALECLIVSQETIKGGDFVNAARRERDLNDLDVHVLELVNEDVGDFVPGQESGEVKMSSTMERHKLLGTLLKPSKPWNTRSANEHSRPYVIGLTGGIASGKSSICRRLEGLGAKTINCDLLGHKAYLPGTKAFDEIVKVFGQDVMSSDGTINRKALGAIVFSDKSKLELLNNIVWPEIMRMVEDKILEYGDLGKKVCVIEAAVLLEAGWDRVMNEVWVSIIPEDEAILRMTTRDGMSEKQARQRLQAQMSNSERVNRANVVLSSLWVPDYTQKQVERAWNGLQERLNNNIGPQSAL
The following text describes a protein:
Function:
Required for nuclear membrane fusion during karyogamy.
Subcellular Localization:
Endoplasmic reticulum membrane. Nucleus membrane.
Sequence:
MARKLLFTALCAVTATPSLAFSWGGERKVAVPDHQVNIDRNIQPSDLLRASSRLPNIYAVALSELQELESEPFCHRVAARLLVNNCQLVDGKNDATILTDTGRQVRDFVDSYAASLAICDLERGRFNIPAQCAKFREPALSQIAIRDQAQLHVSSHEIDHCLSAMKSSDAAWNTWISYRHKALRFCEAARADNEKAQNILLYQRLTNVMKNLTEGVEAQLQKQMNRLDLRTQQSMKNLDNLTPQIDKLRDGLAMVHEYLATDVEATLRRSFASLHDSQQQAEDLQKLLNLLLTGVLEGHSRVAHAHEHALQQVSVRANDGIGALVAVVATAAASTTALQQQIELSNQQAAALALRQDNLEQGMDRLLAVTETLATKYEDQTQRLQQASNITNDILDILENTAEAASSVNESLLTGASSRSWWPYIVCPTASLVMGSYGLPPSAVRNLALLALGEVAGFMISSFEQIAGALQSFEAPLYSSVWETSANTTALPYEI
The following text describes a protein:
Function:
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.
Subcellular Localization:
Cytoplasm.
Sequence:
MIVKTTVSKRQAFRTLNPLSSLFLLCACVACLYSVNLGAASYHPGGPAKYSNYQRLEILWITGCTRPVLTERGRQTISCFSDLNSYHPVQLTVRGRGFPQLGNLSIVLEEHTPIPHHGGEEDLDLISMPCLHVRPSSLFPRQILSCTLLNPMDSLRHKPLWLERLTTRSTWMNLKLLQTVTSDNSNKTTIVTLASVPRAVELDLTPYGNGSHSGGEEDEEEDAEDPLEYMFRRVRHSAMNDEWVSLGIGGLSEQLHELFRRVFLSRTRQLRGVVESLNIPPVRGVLLHGPPGTGKTLIARMIAKLEGKGTRVTIVNAADIISKYVGDSEKNLRRLFDANNMWGDDDDEDEHGGTRHASGADEETANSKSLHIVIMDELDALFKRRADLGEESSTKAVYDGLTNQFLTIMDGVNKARNILIIGLTNRLHAIDRALLRPGRFEVVIEVPLPDVKGRREMFFIHTRELRDKDFLAEDVSLDILAERTGGFSGADVAGTVRAAVSHALLRFRDSSLNTSIPTGDIGIEDELSGAATEHFKVTNSDFQLALRDVWDSKAQVNGGQDLAGDGKGLDNAVDKLVDFDGTISRGMGVVRRLMRSIQHSQITNAAVVVIHGSSGSGKTVFARNVVSSIRFSVTKFLTGRELSGRAARDIQEVIDALRDAGAFKGDYCLVVDNVERYVRSGDSGAADALRSAINEFKSVSSSGLFPHSEWDVSQPRRKRLLIITTAEEEVLQGALGSVEYDVRLNLQPIRREGVLKLLHHYGILPQTAKLPNEVVRAYPTSLTYRQFLRITDLALWRAHEEHHRTAETTSTGEAESLETSLYSSLNELFTKGGPQRSGGDHHSPPVLTESQQAELAAAIRDVASEMGISDAFDGVLNADGSIHGEEMY
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Sequence:
MGCGSSTPEEKVSKQSIETAPKAEQLKPAPAQNQPKKEDSTPKPAPPPPANPQPEPPKQAAPTPQPEPKPEPTPAPPPKPQQEKIVTKGVKDDSGDAYGLLLCGAGESGKTTFTRQLRIKYLDEFTSSERQNFVATMRGNMIEAMQTLLVWLERQRLELENEDLQDLAYEISQMDAFSCEFTEEIAEQLKELWQDGSIQEAFSHKDETIIPDHMDYFFNKIDKIVQEDFQPSDEDILKARIRTIGIDKVTINCDDALIRIYDVGGQKSERSKWEKCMSEVQGVIFCVSFAEFDKPMFESPEIPRIQDALSIFEQVTHKEKFQNAPFFVLCNKYDAFSDRIKNTDAFSKTFPQYQGNPHDPDECAKFMTELFLEKARPDVATRPINTYKLIALDSDNVVQTTNQICKYIREHYFE
The following text describes a protein:
Function:
Anchoring filament protein which is a component of the basement membrane zone.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix, basement membrane.
Sequence:
MRLCLGRPHPRGHSRVGKSERGRGARGLARQRTLEDEEEQERERRRRHRNLSSTTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEAAQAPIQERLEAEEGRNSLSPVQATQKPLVSKKELEIPPRRRLSREQRGPWALEEESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPATTKEQRGRALPGKNLPSLAKQGASDPPTVASRLPPVTLQVKIPSKEEEADMSSPTQRTYSSSLKRSSPRTISFRMKPKKENSETTLTRSASMKLPDNTVKLGEKLERYHTAIRRSESVKSRGLPCTELFVAPVGVASKRHLFEKELAGQSRAEPASSRKENLRLSGVVTSRLNLWISRTQESGDQDPQEAQKASSATERTQWGQKSDSSLDAEV
The following text describes a protein:
Function:
Catalyzes the dehydrogenation at the alpha-beta position of ACP-bound acyl chains. This results in the introduction of a double bond in the lipidic chain, which is further transferred to the epsilon-amino group of lysine residue in the mycobactin core by MbtK.
Sequence:
MTAGSDLDDFRGLLAKAFDERVVAWTAEAEAQERFPRQLIEHLGVCGVFDAKWATDARPDVGKLVELAFALGQLASAGIGVGVSLHDSAIAILRRFGKSDYLRDICDQAIRGAAVLCIGASEESGGSDLQIVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNVAVVAVPAAQVSVQTPYRKVGAGPLDTAAVCIDTWVPADALVARAGTGLAAISWGLAHERMSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIAEQGRLELRTAAAVKVTAARLGEEVISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVAAGMTPDHDGYAAVVGASKA
The following text describes a protein:
Function:
Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 20 in the D-loop of several cytoplasmic tRNAs (acp3U(20)).
Subcellular Localization:
Nucleus.
Sequence:
MAGGEDPFGCLKLASQECLNSLDRRTVCPKCQQSRKYFCYTCYVLVAELEGKVPKVKLPFKVDIIKHPKEVDGKSTAAHAAIIAPEDVRIYTYPIIPEFSDPSKVVIVFPGLNALSLEDLSKKQHGLLKGKDKPQNTEKTQTITPESTDTENGREEKQDNTAAQEEDVEKQSGEVREPPLKKQRTEERVSAPFERVIFIDSTWNQTHRIFTTNDSKVKAQIDALLSLQCVILKNHITHFWRHQRDKPDTFLATVEAIYYFLREFHDIFVGVVYDGRYDNLLYFFSFMFQIVQKSKQEKGRLKDNKDP
The following text describes a protein:
Function:
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
Subcellular Localization:
Mitochondrion.
Sequence:
MLKYAWQSGPKQRNRWLWHLSNQIWKRSYSSKIRNIGILAHIDAGKTTTTERMLFYAGKTRALGEVHRGNTVTDYLTQERERGITICSSAVTFPWNDHRINLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWSQADKHKLPRLIFVNKMDRPDADFEKCVSDLKDKLETQPVCLQYPVKNDDGVLAINDVITLERLSWQKKDLGRSYRNVKLEPSDDLRVLQEKRNELIDQLSGLDDELADVVISTESFDNVDNALIERALRRATAQQKVVPVLLGSAYKNVGIQRLMDAVNAYLPAPEERNQIYDCFGGEIKRGMRLISARGQAEVVSKLYEPLADEYREVGAVQSGDVVICAGLKSTVTGDLLTSTEEDDELDESAELFAIDPQIPDAVYFCSIEPPSVSSQTAMEQALKQLQREDPSLRVSYDSVTGQTVLGGMGELHMDIIKSRILSDYKIDVDLGPLQIAYKETIEAPALTTQSVEKEIAGSKQSVSITLEVVKNQAELFSLDKSPENLPNLNTLRPRILQVLRKGSISALERGPRVGGQVVETQIRLHNATIGRGTADSFVMATAAQCVQKLLSTSGTRLLEPIMALQIVAPSERISGIIADLSRRRALINDVLPKGERNKMILVNAPLAELSGYSSALRTISSGTGSMTMQPCGFSSMNSVDESLAERRAQGLE
The following text describes a protein:
Function:
Plays critical roles in regulating RNA replication and transcription through its interactions with multiple proteins. Tethers the RNA-directed RNA polymerase L to the nucleoprotein-RNA complex. Recruits the M2-1 protein, a processivity factor that is required for efficient transcription of viral RNA. Acts as a chaperone for neo-synthesized nucleoprotein by forming an N-P complex that preserves N in a monomeric and RNA-free state and prevents the association of nascent N with host cell RNAs. Recruits the host phosphatase PP1 to inclusion bodies to regulate viral transcription. Together with the nucleoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway.
Subcellular Localization:
Virion. Host cytoplasm. Note=Localizes in cytoplasmic inclusion bodies.
Domain:
The N-terminus is important for viral particle assembly. The oligomerization region is central. The C-terminus part contains binding regions for the RNA-directed RNA polymerase L and the nucleoprotein (By similarity).
Sequence:
MEKFAPEFHGEDANNRATKFLESIKGKFTSPKDPKKKDSIISVNSIDIEVTKESPITSNSTIINPTNETDDNAGNKPNYQRKPLVSFKEDPIPSDNPFSKLYKETIETFDNNEEESSYSYEEINDQTNDNITARLDRIDEKLSEILGMLHTLVVASAGPTSARDGIRDAMVGLREEMIEKIRTEALMTNDRLEAMARLRNEESEKMAKDTSDEVSLNPTSEKLNNLLEGNDSDNDLSLEDF
The following text describes a protein:
Function:
Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus.
Sequence:
MLILSPDIGSERYIFNFTVRDSPSYFINVNSWGREDYIKSLSDSFRVGDCVIIENPLVQTKEVERDEKFSPTTPSNYKLLLSENHSTVRICSPGEVDPQLLSLLNIPVKDPQDFYSLGDIVANGQSLDGRIINVLAAVKSVGVPKCFTTSDRRKGQRCEVRLYDETESSFAMVCWDNESIQLAQSWMPRETVIFAADVRINFDKFRNCMVATVISKTIITTNPDTPEANTLLNFIRESAEMLDLDDDLGEQFRESVNLQTIADVYTVEQLKSEVVQRVGKPEPFYGIIFAYISTLNIDTETPKIIRNRCVKCHFVVNENTNVCSFCPGFGASSDAMPVFPSFDLFVDLTDHTGTLHSCSFSDTVAEEALGYTVQEFQALTEAQRTALKWHFLLERSKIYFKIIPSASSRTGLRVNLLSCKLADPVEASQNLPLKEK
The following text describes a protein:
Function:
Catalyzes the anaerobic oxidation of oxalate using a broad range of electron acceptors, including ferredoxin and the nickel-dependent carbon monoxide dehydrogenase. Does not require coenzyme A as cosubstrate. Enables anaerobic growth on oxalate which is used as energy source by the bacteria.
Sequence:
MGKVRNISGCVAVAHGVRLADVDVICSYPIRPYTGIMSELARMVADGELDAEFVHGEGEHAQLSVVYGASAAGARVFTGSSGVGVTYAMEVYSPISGERLPVQMAIADRTLDPPGDFGEEHTDAECCRDQGWIQGWASTPQEALDNTLIYYRVGEDQRVLLPQYACLDGYFVSHILGPVDIPDEAQVKEFLPPYKNHHVLDPRKPQIIGPQIEPAMGPPLQYQRYQAVKGVHKVLEEACDEFARIFGRKYDPYLDEYLTDDAEVIIFGQGAHMETAKAVARRLRNLGEKVGVARLRTFRPFPTEQIKERLSKFKAIGVLDVSANFGISCSGGVLLSELRAALYDYGDKVKTVGFVAGLGGEVVTHDEFYRMFQKLKEIAKTGKVEQTSYWIPFEL
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MENKEEARKGPWTEEEDAQLVLYVNLFGDRRWDFIAKVSGLKRTGKSCRLRWVNYLHPGLKKVKMTSHEERLVLELHSKWGNRWSRIARKLPGRTDNEIKNYWRTHMRKKAQQSKKQKKSISPISSSGNSSSSSSISNSPATEDFTPAKETSFYDTGGVEIKDLMIPAAAAAVEPGESKKT
The following text describes a protein:
Function:
Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MFPCGTRIKLKRDSFKPENKPEPNKRRWTGSNVKPVCAVNPPVDGGSPKPATADPGTVSSKVSVITGADPEAMPASKNRLSEHKREIFCRLRLALCFARNKPRNGGKRVIVGPTDAHALSVINSVESGNVNVSVEPPELIPPARQSVKHGAQNTLSRPTVPRREKGTQRRLFAGEAKTAIRTEARRSRASLTGRTSANFSSKVELRRLRSEERSRKRSVKNACCALCGDVKYNPPPPPSSKNLVRLLNPRPRAGRPSLSAEKQRTPSASRHASALEKNPTVKLCDVGRVFRIASRDFSCVLPAVLKQTASRRAQQQCLQTEFGVLTHPHPHSIRKRRRSRKLSTATKHSCASLSSGDAPCGGAHISEGSLEESDACLVEDPETMRLSESPDTVAPACANNCPEKQKHCPVNHISGNTSSPERRVPPLVLRRVSVNGFGFRSEDDDRESGPDEDGRNQDSDAESANAPESFSCQRTQAYIFIPKSSCARTCKPWPFPRTGPPEELRSPRNGARWIITATFTNTAQDDEEKNERSEAAEEVYSRKSHADTPCRLISGDIPDVLNQQSSVLCENTSTCVLKRTSGFSVTAISEHAELNQSQEHSTEQVNSCKLDGCGFEASLEANGLLRHHSLLDHEDHPDAPGVWEPADHLVGDSKCAKFSILPISQFEDQSRKADEGAVYNPALLSQMCIKVGVLKAQDSSSVDQTEGESAAHSHSSNPEGEVKPASDGQTHTDMSSEEENQDAGGVSAPSSSSSDDDDDDDGVCSMNTNNNNNTQACSQSHRVEESFLDVSRAYEEDVLVLDVIQDDPELFGTVVSEAKTQQDAPTKNQDTLTKMEDQHCEVIWEQHTEGTSKVAEDVQTDHLSDSGSKVNEMQVCRSQPVQSLNTVKSENAGIDCNNNQPSRDSSNLNSISVISSRAPRPVTDSCFSGREVTAKEPPALRTPHISYCRFYFSDHSTCLRSGVCRFLHVPRDGDETFCMEMVKKFCHAGKVVLILRAVEVFMGYYSRCPPSGSFSQETVNSLLSILLNMGLLREFLAVLNLLLTHKKLPPPELVLAVFKFASDRRLINFVPELILLTSKIVESGCVFTVDQCEVMQSHLHLMQVPRQQMDIFMAVKCRALATNPHTSELSHLTQAVVRVEMLKQQEDWSGLALVFYSVCSGSHSNNELLRFCCCVTMALLKEPKDKHTVPYELFADAVCQREPSDEVKSILGRIGVSLIFRYHRTREWSKGVKLVNVMLRLQIEFIMQKGLMGNEHRVSRCQLVSMAAELFLHSGSIEGALKLLRADGWFVSSSVWPCEAADVEIRKRVLTLLAGKTSHRDAFEILTNLPGLRQPINGVQISDYTDMFNAHLRVCLLKQTLPVAADILEFMLTRSLVPETQQLQNLIHRLGKQNMWSRARALFRRARSAGFYSSVVCEADALFLPCGLSEIEMTLAFEMFITFINSSLSAHTHPLLITLRRQAGVENVTESVYLAAGCRLLSAALIPNPKLSIRYTAVNQQQEQLFTLDRASAHKWILQNSCWALEVWAS
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MSAIPTEQTRPPEADARDFVEGETQRPQLLIAVQERILQDPILAGHFAGLPTPGVPLLIGDPFNALSSPHQLRTSHRLVRAVDAFGNKYLNQYIVIKLLGCGRYGKVKLCLNAFDGKLFAVKVVDRKRLRDRRFLNEDGDSIMLQEYVHEIATLKKLHHPNIVALHEVIDDVQQRKVYLVLEYVEGGPVMEDNRWIAFPEELAQKYFRDICCGLDYLHYHKVLHRDLKPENLLQTADGRIKISDFGVSQKSRSFLLPKNISIQQACKRHFSTDALSSTAGTPAFLAPEACTKSSFEGRPVDVWALGVCLYVFVFGTLPFSGKTIPDIYHAIQHKQLSFHPSIVISKELKDLLKLILVKDPKIRISLPSIMEHPWLTLFGLQLLIPLSKSVHGAATMDFSKNDLKSAHTTSTSGLNPLSKVGEQEKRFQAGEYAKGQGKQGNKSCFMNCSKCEILVDADPELGGEMDECVVIKREPGKFGD
The following text describes a protein:
Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a/ATP6 in the membrane. Together with subunit g/ATP20, probably contributes to membrane curvature at the site of the ATP synthase dimer, ultimately contributing to formation of cristae.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein. Note=The F-type ATP synthase complex is anchored in the mitochondrial inner membrane via the F(0) domain with the F(1) domain and the peripheral stalk extending into the mitochondrial matrix.
Sequence:
MSATLNVLRWSALGAGVVYGFVHNRTLYSQAEKKVADAKFKKQEKLIEQAKAEWARLHPAPVASTGVVTDISDDKFDIEAYLNHAFPEKA
The following text describes a protein:
Function:
B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
Subcellular Localization:
Membrane; Single-pass type III membrane protein.
Sequence:
MGARRLRVRSQRSRDSSVPTQCNQTECFDPLVRNCVSCELFHTPDTGHTSSLEPGTALQPQEGSALRPDVALLVGAPALLGLILALTLVGLVSLVSWRWRQQLRTASPDTSEGVQQESLENVFVPSSETPHASAPTWPPLKEDADSALPRHSVPVPATELGSTELVTTKTAGPEQ
The following text describes a protein:
Function:
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
Sequence:
MSAIRQERRARAERLLVKLKVAYPRGLTLGLSSTNPFEYLVATVLATQCRDERVNKITPALFARYPDPAAFAAADYEALLPLVRPTGLGPTKARNLTAIGRLLLERHAGKVPATMAELTALPGVARKIANLVLADCHGIVEGVAVDTHVRRISKLLGLTDSTDAAKIERDLMDCLPRDAWRSWNNLMVEHGRQCCVAGAPRCTACPLVEDCPGGRELTAELERRDAAGAVLP
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB1 (By similarity).
Sequence:
MKILKKLKKKLEKEESKILVDTSVLIDYFKKRRLEELGGEAISIITAVEFIRGISEHKQEQVLNIFKELFEIVYIDEEIIIPFSKIYRQLKKRGMLIDDADLYIACTAIIKNYPLWTKNKKHFERLKEFGLKIYDK
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil.
Sequence:
MSAADATWLTLTVQPDQSAMRLDRWLAEQVADLSRARIQALIDQGLVLLNNRPCRPRDLVHSGDAVALTIPAPEPLAIEARPIALDIVYEDEELIVIDKPRGLVVHPAPGHSDDTLVNALLAHCRNLSGINGVLRPGIVHRLDKDTTGLLVVAKTDRAHQHLQTQIQAKTARRDYLAIIAGAPAETTGTIDAPIGRHPVHRQKMAVHPKGRPARTHWRVLERLGNFTLVEFSLQTGRTHQIRVHCLHKGWPIAGDPLYGSVKVPATLNGQALHAFRLGFEHPVTGERLTFESPMPAEMVKLLDALRRRTP
The following text describes a protein:
Function:
Seems to play an important role in controlling the expression of resistance responses like the regulation of salicylic acid (SA) and phytoalexin (camalexin) production. Involved in resistance to fungal and bacterial pathogens. Required for the regulation of cell proliferation in root apical meristems through the GSH-dependent developmental pathway. Also participates in the detoxification process, the antioxidant response and is essential for embryo development and proper seed maturation.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MALLSQAGGSYTVVPSGVCSKAGTKAVVSGGVRNLDVLRMKEAFGSSYSRSLSTKSMLLHSVKRSKRGHQLIVAASPPTEEAVVATEPLTREDLIAYLASGCKTKDKYRIGTEHEKFGFEVNTLRPMKYDQIAELLNGIAERFEWEKVMEGDKIIGLKQGKQSISLEPGGQFELSGAPLETLHQTCAEVNSHLYQVKAVAEEMGIGFLGIGFQPKWRREDIPIMPKGRYDIMRNYMPKVGTLGLDMMLRTCTVQVNLDFSSEADMIRKFRAGLALQPIATALFANSPFTEGKPNGFLSMRSHIWTDTDKDRTGMLPFVFDDSFGFEQYVDYALDVPMYFAYRKNKYIDCTGMTFRQFLAGKLPCLPGELPSYNDWENHLTTIFPEVRLKRYLEMRGADGGPWRRLCALPAFWVGLLYDDDSLQAILDLTADWTPAEREMLRNKVPVTGLKTPFRDGLLKHVAEDVLKLAKDGLERRGYKEAGFLNAVDEVVRTGVTPAEKLLEMYNGEWGQSVDPVFEELLY
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
SHVKRAGVLSRRRICRRRVLRVTARPPAHGKTGDQTSGIVDARASCTHARQRASARRRNARALEHQRRRRLPRRRRLIPPPAAARLDPACSSAARNRTTRWSSATVAATTTGRSGGGTSGGIGPPAPSASAAANPPSASPRPPPSPPAAAAATTAAASLVNRGHDIMVRFDGDAGGVVVDGETYALRQMHWHSPSEHAVDGRRYDLELHMLHQSETRDGRYAVVAQLFDIGHRRDATLDMLEPYIKRVAKRRKGHEVEIDDDVDPRWPVKGSGVYYRYTGSFTTPPCTEGITWTRICRCGACRGSRWSSSARSRPRCK