lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
Sequence:
MSRPMVADDPVELDQLTTLPNGVRVATEALPGHFSGIGIYIDAGSRYENEDLRGVSHIMDRLAFKSTSKRSSDEMLESIESLGGNIQCASSRESLMYQSATFNSAVPTAVALLAETIRNPLITEEEVEQQLETAAYEIGEIWSKPELILPEIVHMAAYKGNTLGNPLLCPKERLSEINSDTIQAYRDTFYRPERMVVAFAGVQHDEAVKLAEQHFGDMPKSAPLLSQTGSETSFDSSSSETSSNSSISSSSSSPPPPSPTQKPSTLISRIPFFKNISTSAPKNASVRNGFINPLDLNHPSHYTGGFLSLPSLPPPMNPSLPALSHIHIAFEALPISSPDIYALATLQTLLGGGGSFSAGGPGKAFNHSYTDSGLFGISASCSPGYVKNMLDVMCRELQSLTLDTGFNALQTAEVNRAKNQLRSSLLMNLESRMVELEDLGRQVQVHGRKVGVREMCKKIEELTVKDLRRVATQVFGGLVNNAGQGSGSPTVVLQEGEEEGRVYKTFSWDDIQERIHGWKLGRW
The following text describes a protein:
Function:
Thiol-disulfide oxidoreductase that possesses disulfide reductase and insulin disulfide bonds reducing activities. Heat shock causes oligomerization and formation of high molecular weight (HMW) complexes with concomitant functional switching from a disulfide reductase to chaperone.
Subcellular Localization:
Cytoplasm.
Sequence:
MAAEGEVIACHTVEDWTEKLKAANESKKLIVIDFTATWCPPCRFIAPVFADLAKKHLDVVFFKVDVDELNTVAEEFKVQAMPTFIFMKEGEIKETVVGAAKEEIIANLEKHKTVVAAA
The following text describes a protein:
Function:
Serine protease inhibitor. Inhibits trypsin (Ki = 30 nM) and weakly inhibits chymotrypsin (Ki = 550 nM). Does not inhibit bacterial subtilisin.
Sequence:
GRRPCCNECGICDRSLDPMCICEDLVPQCHEGCQACEKVDTGTPMYQCRSFEYYHCGPICY
The following text describes a protein:
Function:
Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
Subcellular Localization:
Nucleus.
Sequence:
MTSEGDVIRENDPVFIRLPSENVRFIHAKPNNTISLGKFGSFLTNSLIGQHYDEYFEIYEPRKIRVVQRFTNEELEDESKNNKELVDSGSNQKLQHEEIEKLKGNLKTGSLKDEKLIEQIAQSSTTFDKKTSFAQAKYLARKGEKYFQKFHALKPCMEVIARYMLERDPTKVLDLTPETIGLMLTLANVRPGGRYLVVDESGCLLLGSLMERVNRKCQVMLIHPNEQPNNSCLELWGSSFTEEALKKNESLRTLNWLHAVDPEEELREFEVADIDPEAFEALKPRHKKRYLHRKAFYAKLKSDMEDYAAGNYDALLYVSNYHPKTTLKYLLPKVGLSCPVIIYSPYQNTLVETSHALVSYTHPVSHSEVQEGTEKPVEVEAFDKLLGLDIHEARQLSYQVLPGRTHPLMTQRGDMGYILSAIKVRNFNNILAAGRFPKRSLRAKNSKSAKRTKTETPVQTPVTEPADTPMQEAAEACAK
The following text describes a protein:
Function:
In the process of mRNA degradation, seems to play a role in mRNA decapping. Required for silencing a subset of endogenous miRNA targets.
Subcellular Localization:
Cytoplasm, P-body.
Sequence:
MLIALFALAHLPIFRKTPLSASSSPPPSVHRSPRCGKASTAYHPPPADACISITASAIDAASGMSNSAEQDKPIAANGNAAEPQEIEVIHFQAQEKQCCRVIRSNKTKVLTSGGVHTRGSSKVKLKNIVDYKWERKYYYPGHLVAVHRDGKHLAYAINVNNKATGMEGMVRVCNIATSMRALIKGMSGEVLDLQFAHTDCERILAVIDVSSLFVYKVDQIEGNLLCNLVLKVEDPIANYVPEYDMVSWCPYVCSSSATVPINDDDDENQLLIWSRSSQFQCFQVKMIVSEHGRGKIQPAALESGYLKIEEDSLITCAALSPDGTTVAAACADGLVRFYQIYLFDVRNHRCLHEWKPHDGKKVCSLFFLDNINKPVEESYWQHVITTSDANTEIKLWNCSLWKCLQTINVVASPSSLQPRNFIAGIDRSANYLVLSCLDSLAVYVMQIGSTGGADSENRSSDSEGEGCDTSKRIQNVAEFKLSSGILSFSIVNASMRRVKNSIESYYPIEEPDDFDDDSNSTSALVLHMFVVQAKSLQECQIIYQPCVAEKTERSSLNSKRSQTPEDNLLIKEEPESPNSGTVGAVQLDALFAKSAKRASTGSSSAMVAVAAAAAAAPSAILQDATKEAAKSESPQLSSAYTQQVNLMTPDAFSASGTAAAAAVFVSTSTTTSIGTDSSTTTSGQDRSIDSAVLQTIRMLATVTSKTSENPNAEVLLNLMNNTLIEDREQQKLKEKLDARKKFIAIDRNPERNVAENLASGSSSPSREVQEIMATQDDADAYEAELENLDDDDDDEEEELANSSPLPEAVDGTWPIVKLSSHSAELQNAAQIMSQAVQNTNNGNVPPTLGGGHNNNTSVGSNSNNNTATTLSTSNTSSSNNAGGTCVDSSGTGELNAKMELLIDLVKAQSKQINKLENEVNKLQKQQEAAAALHSKQDTSLEPKNLSQLAYKIEMQLSKLMEQYLKRYENEHKKKLTEFLAARESQNRELRDSVLQVLNQYVMNHFTDIIGNVLNMELQRQLLPRVNANMDQLQAQMQVEIVQKLSVFDKTVKENIAQVCKSKQFLDTFGKSVLIGVQTSLQTAFIESMSSTLIPAYEKSSQNMFKQLHDAFSVGIKDFMVQFNTYLQHMPQPQAGSGNTEEINNKLSMLKQLVESSLHKHRTELTDAMLETQREVKSLEILLARQVQETIRAELRKHMEAQNVAMRSQAATPAPPYDLRDSIKQLLMAGQINKAFHQALLANDLGLVEFTLRHTDSNQAFAPEGCRLEQKVLLSLIQQISADMTNHNELKQRYLNEALLAINMADPITREHAPKVLTELYRNCQQFIKNSPKNSQFSNVRLLMKAIITYRDQLK
The following text describes a protein:
Function:
May be a ligase forming an amide bond. Shows ATPase activity (By similarity).
Sequence:
MKRVTGFPTRPDMVQQLLNVGFDYYNLPSSDGSHYWSDNVAYEFTLAEIDRIEDTTNELHSMCLDFAADEIKKGDYENYHFTELQKQLIETSWRNQEPYLYGRFDFGYDGNNLKMFEYNADTPTSLLEAAVVQWQWLEQIEGLKHRDQFNWIHEELIKHFQFLKQQSGKTDFHLSAMQDAGREDWGNVDYLADVAYNAGWNIHQLAVEDIGYNSETKKFVDLNDQPIEMLFKLYPLEWLSHAEFARHITTAETRFIEPAWKMLLSNKALLAKLWARYPNHPHLLPAYFTPFELPKDLSMWVKKPLLGREGANVFYYEKNNGVEFAAKGSEHSTFYGNSGYVYQQKFELPSFDGMYPIIGSWVVGDVACGMGLREDFTAVTGNDSHFIPHYFVP
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm.
Sequence:
MLLVIGSKNLSSTNM
The following text describes a protein:
Function:
Regulates silencing of the mat2 and mat3 loci. Organizes the chromatin structure of the mating-type region where it also participates in establishing the 'cold spot' for recombination. Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing repressor complex (SHREC).
Subcellular Localization:
Nucleus. Chromosome, centromere. Chromosome, telomere. Note=Associates with major heterochromatin, centromeres, sub-telomeres, rDNA and the mat locus.
Sequence:
MAEPDISSSETLTELQQLRLLYFFCFYHAAPFNVKTLVHSLIPPGALSYLLSTYDILRPWLMALRVREGPVNDISTIVQLYEEIVKTGFFINPPPFESYSQTLVARITTLGRPKLQVQQEAQSEVYQRASTNTQQQVSNVSHGNFKPNSSVNTEPNTSILSNSKYAGIKPFDFQSSSQNPGLVCEQKTFYQHQFRPFSNLPSNKSSPVKHVSPNVKNNSKKTASSVNSNHSSIPSSITKSNISSLDVYGSEKLISSGSQQPGHGMVQTTSDKVNASASLYDRSPSKKDITSSRNTSSYNLGSMRNPSTLKNAAHANPFEGLRFQGSSAVLKEGLNSTVKKTFFDNLNSEKVCPSVSPFLTPDNIASSILYSTASFSRSKPDRPRLNLSLELKLMQNELNKGQLKKQFKGDLRNLADWNNLSLVSSKFPSLPITNLRPDGSFLKHRRFNEEIAYNRQTLEKAIKQLDLSPDKVIQLREQNGVAVNGRVCYPTRNKHSEISAQSSSSLGVTKSLASEVYSSSTVDTISKLNTDKDNYLIKSKKEPIQQKSVSSETTLVKPSSTSSYIDTTNNVLKTNSSFKSSGLTSGPRNEKELLPEGIPTSHNNSETQAQTADVSNIAASADGIYNSDQEKPPEKLDVTKRAFGREIENSNEKELLTSTFLSPSAESQVCLAEIKTIRPGLVPKKQFSVDQNNVISDNTDCSLPKPSNSKLSSISSDGDASSNRMAVPDKSPFVHAAPNSKALTKDSFSTHISVSSLLHSDNEISPIDSTRKDYFTSKDSNLQTLKEDASSTKQAKDSGTNDFDKLISGNDVSKNNSGEEQSRSALKPLISGKLSSCESINLTKDISTVKRKEYFGIESTSSKQPFHDTGSIKIPAKRSFDTIDKDFRSSNIPFADKIKEDGGDKNVISSIHITTELPKSMPVEVPTNAGAQSDQSNVVDSESLNLRENISTSVADVSLSQAGNEAVLSKKACKPLVLIDPFEEKVLKAFNMLSKGYAEYRCQWEGCLANLHSLENFIKHVLLLHHPKSCSVVKCLWASCDMVLPSEEFEMHLRGHLNNIRLNCEVSNCKKCFSNYEDMFKHLQHSHLPFKFTPESFIKIRNGNVKEEARRTRNAYTQKSGEVECFMETCTPIAKPAPANWYPVPPPGFNSSLLSRLTQSNQSKDKIIAALAKRNVYKSFAGLYDSKGKNDNTGYDFDSNYARVGRHGSFILPVSKSVPTPSLLIEGSIVQRKNIKIE
The following text describes a protein:
Function:
Transcription factor that activates the nmt1 promoter. Regulation of thiamine repressible genes. Positively regulates conjugation during meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MNEEIGFLKNQLFADVKDLERKKKRRVPPEQRRRVFRACKHCRQKKIKCNGGQPCISCKTLNIECVYAQKSQNKTLSREYLEELSERQLCLEYIFSRMCPNFNLETKNLISISKKLSENENLPVSKIAEVTNELDTLVRINDQLSRNHISGTTEEMQSSSSLIAGEVQPGISFRDQLKVGKLEDTLYLGPTTSEAFIERLQNELELESISEDDLYSKRLSPSVSYSEFDEQLLLHARSLIPSKAVVEFLINSFFINVQTNLFVYHPHFFKCRLEIFLAMENQIDAGFLCILLMVLAFGNQYTAEQQEDVSKSNFHASNIGNRLFSAALSIFPLVLLQSDVSAVQSSLLIGLYLQSTIYEKSSFAYFGLAIKFAVALGLHKNSDDPSLTQNSKELRNRLLWSVFCIDRFVSMTTGRRPSIPLECISIPYPVILPDLEIPGSQSIVENMRAVINLAKLTNEICDSLYWNPSPSFESQVNSVRRIYARLELWKSDLHSSVVFDESAVQHPLFRSNAHVQMIYDNAIMLTTRVIMVKKLKDKDLTAENRRYIQLCVESATRVINIAHLLLTHKCLSSLSFFGLHVPFASAPILLLSLHYENSQDIQAVVTKLWQVLEFLSSRCEFARESLNYLKSFNKQLSRRNAPDINNPIADFQNSFQNWQSWVGDMSHGDMLSTFKLTGESSNGSNSTPNEAFQPFDQTSSLYNVPGLNKSYVSNQPSLLTPETFLPDPVLNLEVDKQWTAPTFLSWTELLGPTNVSEQSSHTAEQTSNLTLEKNG
The following text describes a protein:
Function:
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid (By similarity). May function in both olfactory and gustatory systems.
Subcellular Localization:
Secreted.
Sequence:
MKFTLFCIALAAFLSMGQCNPDFRQIMQQCMETNQVTEADLKEFMASGMQSSAKENLKCYTKCLMEKQGHLTNGQFNAQAMLDTLKNVPQIKDKMDEISSGVNACKDIKGTNDCDTAFKVTMCLKEHKAIPGHH
The following text describes a protein:
Function:
Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
Subcellular Localization:
Cytoplasm.
Sequence:
MLSILICFIIFAVTMFFFHLREKRSSHSQTTVIAPLAITYPKPDISGYPLPDLDHATKKPKSRKSKSRQTKPDVSCNPSKRPVLPITPENKEGEDLVEQIQQLKAALIKSNSDLHQQQQTTQSVELREKLQIERNETLTKELLEQTTNNEQLRQQVSSLLAEKEELTAQLELDRVQTNKVLEMQAGCYAKKVRKLKKEFADANKSDKPITKEMGCGPDVDAVATTPTESIVKDVGTPQVIPPRTRTTQQIDKNKSTAPKPKVHFPVGDVRYKDKPVSGYVVNPDGTQVTYGDAVPSTRKPAAANPTNNTEAAGPLVLEQPKPKPYTNNGPVKIDDLVITTTPVERISLPGNRLMLKNVPEGDYGKIIGGGGSNIRRLETRYQIVARINTSPDGNVSFLITGNTEEVRQAAADDVVDGLTVTAEFPNSKLLKRIKTFRLHEIGRKYFVRINRPSDINGMITLTGRLGSCQSAYAEMMGQEIN
The following text describes a protein:
Function:
Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MYNLCGSLLDRWYNVKFNLIQYVYDIDKQIRQNDKVIHILNETIKNDVGIEVRNPSFILKQRIEKLKRICSSIIWFSYRKKIPQFQISSLTSDTGWGCMIRVAQMALAQVIRHYHSFTQPEQLIVLIRHFLDDDDDELINFIKQDQKNQVQYYHAPFSIQKIVYHAKVEFKKEPGDWYKPNEILETLNYLFKYSQYSLNMQIYINYQCAFILQDAIKQMFNYDKGNQEWLKECIKNNNQFISQHDKGIAIFLPARIGLQRVNQDYLEVLNILMTLPYFQGIIGGVTNRAFYIVGRIQDYLIYLDPHFVQNAQNFEDLSKTQASYTCQNIQLIHNKSIDPSIVVCLCVRNGLELLDLWHSLNHMKQEFQEFFFISILDTNVELQISESFQYLDENHELVNILK
The following text describes a protein:
Function:
One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Bacterial flagellum basal body.
Sequence:
MSGEKLSQEQIDALLKAVNEGEEMPAFAQEAGKQEKFQEYDFNRPEKFGVEHLRSLQAIASTFGKQTSQTLSARMRIPIELEPSTVEQVPFTSEYVEKMPKDYYLYCVIDLGLPELGEIVIEIDLAFVIYIHECWLGGDSKRNFTMRRPLTAFEFLTLDNIFLLLCKNLEQSFESVVAIEPKFVTTETDPNALKITTASDIISLLNVNMKTDFWNTTVRIGIPFLSVEEIMDKLTSENIVEHSSDKRKKYTSEVEVKVNQVYKPVHVAIGEQKMTMSEIEQIEEGDIIPLHTKVSDELLGYVDGKHKFNCFIGKDGTRKALLFKSFVE
The following text describes a protein:
Function:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by taf1), facilitation of DNA opening and initiation of transcription (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Note=Localizes at the barrier septum.
Sequence:
MSQLVDVPARGHQKVAIDIDFASQTIIGRTDITVNPIDSNLQKIVLDCYQAEIHSVYVNGDLTKFSYSDALKKLRIDEPNSTVNQHHQLNLQYEALMNDLGGINIFLSKPPGDELRPLIVSIDFSVHQPIFGITFVGIDPVDHRYPHVFTNNSIIPYSTCSWLPCVDGIWERSTWEFEITLPKTLSSLMHREKTQPSDLNNGANGVDGHDDNYENNRFDHQFNLSNEPDLLEDHDIEVICCGDLLDQVTHPKDMRKKTVYFSVTTPVAPNYIAFAAGPFKHINLTDFREPEDDDAMGSSAIDITGYYLPKYAEEVENTCVFLYKAMDFFVREYGSYPFNSFKLCFVDETNFPIISTPSLVISSNSILYPKDSLDQIYDSTKTLTWALASQWIGVYLIPKAWSDLWLIYGLSYYICGLFLKKLMGNNDYRFRLKKQVYRLLELDIGKPPISQRNINIPIDPNTLDFIALKSPLVIHILERRLTKTGGSLGMSRVIPKLLLQVMSGDMLNGCLSTSHFLKTCEKASHMRLDVFAQQWIYGYGYPIFRVVQRFNRKKMIIEMGIDQVQTKEAPRAPMSDKNFLSDAIRHLNNESIPTGLPVFSGPMTIRIHEADGTPYEHVVELKDSFTKLDIQYNTKYKRISRNRSTKNVKRDGDHNGDDSDYVIRSLGDVLQSDEDIERWHLYDYTKEEEDTMATEAFEWIRVDADFEWICDLRVRQPEHMYVSQLQQDRDVVAQLETIRHFTSESFTVSQQVSTVLLRTLLDNRYYYGIRQEAARALARCAIPELDWVGYYHLRMAYLEKFCFKDSTIPKSNDFSNITEYYVKCAMLESFPNIRDRKGVTPSSVKKLLLDLLCYNDNANNEFSDAYFICLLIDSLVEGLIPRGETVQYAFSDPEHMEFVNQVINEIDRYMRIDACMPSFKNIITCKSLKAKLRLAQTFHLEFGPKELLPYTQEGNYVLVRCIAFNLMLQAGALKYTPLIKYIFYILTNDLSPVVRRSLLYSVQDGLGALARGGTKSDVASEDLIVEEDITKAVEKRIDITSRASISGAIEALRNDLGQNHDFATEIWNAINNPKSDLLTKRNLLMICRVLYKAKSSLLVTLKIPSLIPRLRAIHLGKGKIVIKKAPLKQITSKTKEKSTSPTPPSITINPIKPKGPTLKIKLTNLRSTPPSH
The following text describes a protein:
Function:
May play a role in regulating cellular proliferation.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.
Sequence:
MALKRLKTKKSKRLTGRLKHKIEKKVRDHNKKERRAAKKNPKKGSKKQKLIQIPNICPFKDDILKEVEEAKQRQEAERLARREAFKAEREQNKFKTLESMVEDADMRSTVHGIMHENDAQDQDEKKYKNAVTKEQSLKQYFKEFRKVIENADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNKADLVPRENLNNWIKYFRRSGPVTAFKASTQDQANRLGRRKLREMKTEKAMQGSVCIGAELLMSMLGNYCRNKGIKTSIRVGVVGIPNVGKSSIINSLTRGRSCMVGSTPGVTKSMQEVELDSKIKLIDCPGIVFTSGGENSHAVLKNAQRVGDVKDPFTIAESVLKRASKEYFCTMYDITNYDTFEEFFAKKAARMGKFLKKGVPDVVAAARSVLNDWNTGKIKYCTQPPEVQEGQSVHISASIVHSEAREFDVENFESMETEILEHCAVKTDDIMEITSTGPLEIRQPREEAEPADKITASLVIDEKEKPAKGRKRKLDEEKEKVDPSLLLEENQSLNKGIKQMQKLKKKQNVRNEKKISKITDVLDSFSLGPSSSKAEKYDFDEDYVIE
The following text describes a protein:
Function:
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MVALSNALSRVFGSLAGYKFPSFIQKGINALYVKIFKIDLSEFEPLENYRSLNALFTRSLKKERPFDKSPNICIAPCDALITECAFLDNDSALQIKGMPYKAHELVGEINPLSPSFFYANFYLSPKDYHHYHAPCDLEILEARYFAGKLLPVNKPSLHKNNNLFVGNERVTLVAKDIQGNRLYFVAVGALNVGKMRFNFDKNIQTNAKARFTQTYSYNPPIKVKKGDNLGNFEMGSTIVLFIQNTAFKDLKEKNVKFGESIGEFHAN
The following text describes a protein:
Function:
This promotes the activity of RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MNPMSTQAFMGTQAVPSVLHPDNLQQQEQLLLSLLTHIKDQYSTLITTEQTKQIDAIVDSFVSEGHKTEKEQYGGTRNHILTNLTQEPAISPGDYNEGGHSASTLEIVSVGGTTNSRKRKRVEEYVPLDHTTKKLTGSELSLNNSPFKSNETGKTPQSASMVRPGIQSLCDRFIYFFFFSYLFLPEAICKETLNGHVNVLTRNHCSYLLQSEWPCQCSDCNIVYCSPDSASTCCNLNGHVNVYLLLTRLKIFAFTCCNLNAHFNVLISSQNDRRTIHLKPREPRHSLFRNVAGASEPNKVNRVIAGPHDTTGHGKQAPTVASTTAVPHGNIRLAPRKASKVEDAKPTPTPAPAVASPESAKGDTNHPLDGRSLERKAAIQRERARRLVEQNRMFASRKLSLVLDLDHTLLNSTKEELFKRKEEQDRAKPQRHLFRLRHMGLWTKLRPGIWNFLEKANELYELHIYTLGSRPYATAMAKLLDPTGSLFGGRVMSGRDDGDRMVSQRKDLKGVLGLECAAVIMDDTPSVWPSSQPNLIAVERYHFFPSSRRKFGVPGPSLLEMDRDEREEDGTLASSLAIIQRIHDDFFSRHADGDFRKLLLRS
The following text describes a protein:
Function:
Chorion membrane (egg shell) protein; plays a role in protecting the egg from the environment.
Subcellular Localization:
Secreted.
Sequence:
MMKFMCICLCAISAVSANSYGRSRGGYGGAPVGGYAYQVQPALTVKAIVPSYGGGYGGNHGGYGGAYESVPVPVSSAYSGANVGSQYSGSGYGGAPPVDAQAIALAKLALAAPSAGAPLVWKEAPRYAQPVYPPTSYVNQEYGHSEKVKGGSAAAAASSVAAGKKGYKRPSY
The following text describes a protein:
Function:
Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Catalyzes removal of a phosphate group from ADP-ribose 1''-phosphate (Appr1p), but with low efficiency.
Sequence:
MEVLFEAKVGDITLKLAQGDITQYPAKAIVNAANKRLEHGGGVAYAIAKACAGDAGLYTEISKKAMREQFGRDYIDHGEVVVTPAMNLEERGIKYVFHTVGPICSGMWSEELKEKLYKAFLGPLEKAEEMGVESIAFPAVSAGIYGCDLEKVVETFLEAVKNFKGSAVKEVALVIYDRKSAEVALKVFERSL
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MFEDLKPHLQELRKRLMVSVGTILVAFLGCFHFWKSIFEFVKNSYKGTLIQLSPIEGVMVAVKISFSAAIVISMPIIFWQLWLFIAPGLYKNEKKVILPFVFFGSGMFLIGAAFSYYVVFPFIIEYLATFGSDVFAANISASSYVSFFTRLILGFGVAFELPVLAYFLAKVGLITDASLKAYFKYAIVVIFIVAAIITPPDVVSQIFMALPLVGLYGLSILIAKMVNPAPKDNENNNENNNENNTKENTKSES
The following text describes a protein:
Function:
Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.
Subcellular Localization:
Nucleus.
Sequence:
MAAPEQVPLSRGCQVPSTPPLPRANRTLLVRHLPAELTAEEKEHLLKHFGAQAVRVLSDKGRLKHTAFATFPNEKATIKALSRLHQLKVLGHTLVVEFAKEQDQASSFCQTSYSEKKKRSDEPVEEDKEKKEPSCLTIENGIAPNHGLTFPLNSCLKYLYPPPSSTILANIASALASVPKFYVQVLHLMNKMNLPTPFGPITARPPMYEEYMPVHVPLPPVPPLPPEEPPMPEEGEGSSGEESEYESGDDEARERMTKLMELANFQPKRPTTAKQRRVRKRQKIKDMLNIPTSTSHSNLHPALLPSDVFEQPQPVEHKKIEFNISSGIPTSFVKDLEGEQNSDLSAPGDTTNEGFGKIFPTPILNDKEEIQEDSDEIPAEFVSRKELEKGRISKEEMETLSVFKSYEPGDPNCRIYVKNLAKQVEENDLKFIFGRYVDFSSQTERIMFDIRLMKEGRMKGQAFIGFPDEKAAAKALKEANGYVLFGKPMVVQFARSARPKQDPKDGKRKR
The following text describes a protein:
Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MQEAIILLALLGAMSGGEALHLILLPATGNVAENSPPGTSVHKFSVKLSASLSPVIPGFPQIINSNPLTEAFRVNWLSGTYFEVVTTGMEQLDFETGPNIFDLQIYVKDEVGVTDLQVLTVQVTDVNEPPQFQGNLAEGLHLYIVERANPGFIYQVEAFDPEDTSRNIPLSYFLISPPKSFRISANGTLFSTTELDFEAGHRSFHLIVEVRDSGGLKASTELQVNIVNLNDEVPRFTSPTRVYTILEELSPGTIVANITAEDPDDEGFPSHLLYSITTVSKYFMINQLTGTIQVAQRIDRDAGELRQNPTISLEVLVKDRPYGGQENRIQITFIVEDVNDNPATCQKFTFSIMVPERTAKGTLLLDLNKFCFDDDTEAPNNRFNFTMPSGVGSGSRFLQDPAGSGKIVLIGDLDYENPSNLAAGNKYTVIIQVQDVAPPYYKNNIYVYILTSPENEFPLIFDRPSYVFDVSERRPARTRVGQLRATDKDLPQSSLVYSISTGGASLQYPNVFWINPKTGELQLVTKVDYETTPIYILRIQATNNEDTSSVTVTVNILEENDEKPICTPNSYFLALPVDLKVGTNIQNFKLTCTDLDSSPRSFRYSIGPGNVNNHFTFSPNAGSNVTRLLLTSRFDYAGGFDKIWDYKLLVYITDDNLLSDGKKAEALVETGTVTLSIKVIPYPTTIITTTPRPRVTYQVLRKNVYSPSAWYVPFVITLGSILLLGLLVYLVVLLAKAIHRHCPCKTGKNKEPLTKKGETKTAERDVVVETIQMNTIFDGEAIDPVTGETYEFNSKTGARKWKDPLTQMPKWKESSPQGAAPRRVTAGEGMGSLRSADREEDELSGKAWAEDAGLGSRNEGGKLGNPKNRNPAFMNRASPKPHPGK
The following text describes a protein:
Function:
Has weak antibacterial activity, mainly against marine Gram-positive bacteria like C.maltaromaticum (MIC=200 uM), C.mobile (MIC=100 uM), C.divergens (MIC=200 uM) and C.funditum (MIC=200 uM) but also against C.glutamicum (MIC=50 uM). Has very little or no activity against Gram-negative bacteria.
Sequence:
MGPMKVLLVLLVVMVAAPHIADAWQQPSCSSICDYSCGKSACISYSGRCGCCASCRRGPIYG
The following text describes a protein:
Function:
mRNA-binding protein that binds to the SECIS (selenocysteine insertion sequence) element present in the 3'-UTR of mRNAs encoding selenoproteins and facilitates the incorporation of the rare amino acid selenocysteine. Insertion of selenocysteine at UGA codons is mediated by SECISBP2 and EEFSEC: SECISBP2 (1) specifically binds the SECIS sequence once the 80S ribosome encounters an in-frame UGA codon and (2) contacts the RPS27A/eS31 of the 40S ribosome before ribosome stalling (By similarity). (3) GTP-bound EEFSEC then delivers selenocysteinyl-tRNA(Sec) to the 80S ribosome and adopts a preaccommodated state conformation (By similarity). (4) After GTP hydrolysis, EEFSEC dissociates from the assembly, selenocysteinyl-tRNA(Sec) accommodates, and peptide bond synthesis and selenoprotein elongation occur (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MASERPREPDGEDSIKLSADVKPFVPKFAGLNVAWSESSETRVFPGCAATYYPFVQEPPAAEQKMYPEDMAFGAPTFPAQYVSSEIALHPFAYPTYTLESAQSVCSVPTLQYDYSQARCHPGFRTAKPRHEHVCPPPQEAKGVFKKKPSDERRACEEQKSSSRRADNAVPCEARPARGSSHLSSRTESSLKSDGYHKRPDRKSRILAKSASTSKPEFEFSRLDFPELQSPKNSNMPETQKPPRWGPLGPAASNMPLLGDVGKPVADMVEGKMVKSDHTDGAVTSNATTSSPSCTQELSWTPMGYIVRQTVSSDSAAATENVTSMINLKKTTSSADAKNVSVTSEALSSNPSYNREKRVYPAPKAKASQGGELEQNESSKKNKKKKEKSKPSYEVLTVQEPPRIEDAEEFPNLSVASERRHRGQSPKLHSKQQTQNEFKTSGKKSQVPVQLDLGGMLAALEKQQQQQHASHAKPSSRPVVFSVGAVPVLSKDASSSERGRRSSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERMQQRLQESAVSLTVASDDSQDVESGASNQTPSQDNPTGPEKTEESVSSTPVVEGESEEPAGTEFQRDPEACQPAPDSATFPKIHSRRFRDYCSQMLSKEVDACVTGLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKTQSKGGLDDTLHTIIDCACEQNIPFVFALNRKALGRSLNKAVPVSIVGIFSYDGAQDQFHKMVELTMAARQAYKTMLETMRQEQAGEPGPQSPPSPPMQDPIPSTEEGTLPSTGEEPHYIEIWKKHLEAYSQRALELEDSLEASTSQMMNLNL
The following text describes a protein:
Function:
Transcription factor that regulates expression of the genes related to ergosterol biosynthesis, including erg3B, erg24A, erg25A, as well as cyp51A that encodes a target protein of azoles. In coordination with ffmA and ncaA, is responsible for the expression of the ABC transporter abcC/cdr1B/abcG1 related to azole resistance. Directly binds both the cyp51A and abcC/cdr1B/abcG1 promoters at a conserved 34 bp region called the atrR response element (ATRE). AtrR also binds to the promoter regions of both the sterol response transcription factor srbA and atrR genes themselves, the latter suggesting the possibility that atrR is autoregulated. Also regulates iron uptake, most likely via cooperation with SrbA. AtrR is necessary for hypoxia adaptation and virulence.
Subcellular Localization:
Nucleus. Membrane; Single-pass membrane protein.
Sequence:
MDGIGDGTESMGFDMPMLMNQQPHLFGSYGHDGSPVAPIFSNPTFQDEPSIGAADDNSDAKRRRIARACDMCRKKKIKCDGKMPKCSHCTNYKTDCVFTQVEKKRNPPKGAKYIEGLENRLGRMESLLRLSGLLSEDDGGKTDLGTLEKRLADRYHASGSNTPHNPQKINIPSQSQIAMSQQNSSSHYSTPRLESQSSPRTAATSPESQKESETEVEGLSDMMCSLVTNNCGETRYIGSSSGFSIFSPKGIQWVNEKTGDNSFQEMISSAYVDDNKWMYWKPEIFSDIFARRVFKPLPPKDEAMSLFKDFFDNFNCMFPLYHEPTFMHLVERQYSRDPYEGSGWWASINVVLAIAHRLRVMSNLVPQEEDRKAWLYLKNAMGVLTELTMRNTDLLSVQALLGMSLFLQGTPNPQPSFFLVAAAIRLSHSIGLHKRGSGFGLNPVEVEQRKRVFWIAYLLDKDICLRSGRPPVQDDDDMNVELPSDDPPDNIGNVPLSDGRSKFNLFRSMCRFATIESKVYKRLYSAKASKQSDGELLNTIGELDKELEDWKDSIPLDFRPEHEIKASHTPLILHVVVLHFAYYNCLTTIHRMSVHHGYWTSRLSNYAIQGLNARPLNPRVFLSAVLCVTAARASINLIKYIPQGDFACVWLILYYPVSALVTLFANILQNPSDARARSDVKLMNVVVNFLSTLVSDESNGSIKRMLGLCGEFERIAKVVLDKAEKESYSKKKRKSPEEPVNLQQSTPEEHPAPSPSTTQPTQAPSRNVPMSSPLFAENPGDPGGNTMADDAGGFASSREIPGTTGVSTNIPPNIQAMPGIAQDYQDMLSPDPLEGVSFADQPPYSATANTPLSSFQQPFVPQDLWQMPMTIEWDWADMSTNFPVFDTNGPPHGGL
The following text describes a protein:
Function:
Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction (By similarity). Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway (By similarity).
Subcellular Localization:
Early endosome.
Domain:
Coiled-coil domains of PPP1R21 are essential for RNA binding.
Sequence:
MTDLQSKYSKLAQEYSKLRAQNQVLKKAVVDEQSSCNSLKDELKQKEQSLRRVEQEMDSLSFRNQQLMKRVELLQEELLLSESKSKKSRSKGDSPSQVSLQAQSVFDEDLHKKIQENERLHIQWLEAQEQHQQQEAQLSSRLQQLQEEAQEHQAQLEELSCRHAHTIHTLQEDKATLEVKLQTLEREARDCRVRTEECQQQLRKYQSEVSSQLKHSSSVIQEKVPFNDTQLSDYNSLNVPAHNRRHQLRAREVAAQALVFLQNLVSALLNFHSYSEQRVQIYPRDSSIETISAVNQKFSQYLHENASYLRQLEEDLLQLHQSITEDLPAATQKFCTTNECLLSSLASLTSSSGKMATFFSNSLDFLTSCAGYSPSGALLKPLQADSVMQSKRRAAAYISSVRQARAESVPYGEALANRHILTSSTESREGLMQQVLQSQQKISRLEQEKEHWLLEAQLAQVRLQKESARIAQLEAQVCVSAPQSQLCASAAESPVCVSAAESQVCVSAAETPSEPALADAPEPLQDTSVVGVLSIRSCSESSADQDSREQLIKTHYMSRVSELTTQLQICDSKAVHFHAECRAVAKRLAMAERSRDTLGEELKLANQNITRLQDELSTTKRSYEDQLSMMSDHLCSMNETLSQQRETIDTLKLSAKGNAKKNKSR
The following text describes a protein:
Function:
Alpha-ketoglutarate-dependent dioxygenase that in vitro catalyzes the regio- and stereoselective hydroxylation of L-lysine, leading to (3S)-3-hydroxy-L-lysine. Can also use (5R)-5-hydroxy-L-lysine as substrate, but neither D-lysine nor L-ornithine.
Sequence:
MKNLSAYEVYESPKTSGESRTEAVSEAAFESDPEVSAILVLTSSEASTLERVADLVTAHALYAAHDFCAQAQLAAAELPSRVVARLQEFAWGDMNEGHLLIKGLPQVRSLPPTPTSNVHAVAATTPMSRYQALINECVGRMIAYEAEGHGHTFQDMVPSAMSAHSQTSLGSAVELELHTEQAFSPLRPDFVSLACLRGDPRALTYLFSARQLVATLTTQEIAMLREPMWTTTVDESFLAEGRTFLLGFERGPIPILSGADDDPFIVFDQDLMRGISAPAQELQQTVIRAYYAERVSHCLAPGEMLLIDNRRAVHGRSIFAPRFDGADRFLSRSFIVADGSRSRHARSSFGRVVSARFS