lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MLANTEEKPKMATFTDEIPYLETFTKDKHNIQTNAGERPSMDTYTGERPSIETNTDEKPSMETHTVERPSIETNIAEEPSMESHAGERPFFEINTEEKPFMGTHACETPSMQTHAGERPSMQTHTCESPNVQTHAGERPNVQTHAGERPSMQTHAGERPSMQTLAGERPSMQTDTSERPNVQTYTGERPSIQTHAGERLSMQTDTGERPNVQTYTGERPNVQTHTAEKCNMQTHTGKRPSIQTHAGERLSMQTDTDERPNVQTYTGERPNVQTHTGEKRNMQSHTCERPSMQTHTGEKPNVQIHDVEKPNAKTYAGKRPSMQTHTYEKPNMQTHAGERPSVETHAGERPSVETHAGEGPSVETHAGERPSVETHAGDRPPMQTHTDEKPNPETHTGEELYMQTITYTCGRCKQTFSSLCEITLHMHAHTGERPFRCYVCGKKFLNQGHLLAHVRTHSGEKPYRCEECGKEFNTQSARKSHMQIHAGEKPYKCEVCSKQFMLPSLLKSHMLTHTGERPRPYSCNLCNKKFQHKLGLKTHMLIHTREKPYGCMECGKQFRSQYNLKAHMYTHTGEKPYQCEECSKQFSTLSDCRRHMKTHSREKPYKCEKCSKQFKTSGYLKTHALTVGHTLTQIGGQTLSHADGHTLAHSDGHTLSHTDGRTLSHTDGQTLSHAGGHTLSHTDGQTLSHTDGQTLSHTDGHTLAHTDGQTLSHTDGQTLSHADGQTLSHTDGHTLAHTDGQTLSHTDGQTLSHTDGHTLAHTDGQTLSHTDGQTLSHAGGQTLTHTDGQTLSHTDGQTLNHSGEKPYACDVCEKKFQYQCNLTEHMRTHTGEKPYSCEECSRQFSFQCSLKRHMRTHTGEKPYSCEVCGKQFRDASSRNKHMWTHSQSGEKPYKCEECSKHFVTLSGLKSHTMTHTGEKPYSCDLCNREFRHRYGLKIHMQTHTGEKPYGCKECGKQFSQASNLKQHMFTHTGEKPYKCDQCSKEYSVLSCLNAHLKTHSGEKPYMCEKCGTCFRTMTNLKKHMLIHAGEKPHMCEKCGMQFRTLPNLKAHMRTHTGNKPYSCEKCSKQFGRMAHLRLHIRTHTGEKPYKCEECGKQFSDSSACRRHMRTHTGEKPYSCEECGKQFNQPSGLKRHMRTHTGEKPYNCKECSRQFSEPGALKSHMLTHTGERPYSCEHCGKIFCFASALRTHMRTHTGEKPYSCKECSKSFSHTNDLKKHMFTHSVEKPFCCEECNRRFCSAKDLRRHILTHTGEKPHKCEKCSKCYADSSGLRRHLENHHNEEKPTMNTGERPSKETHIGERPSMEALTGDNLHRKGDLKEDQRTHTGEKPYKCKDCGKQFKRRKNLKVHRQTHKGEKPHSCDKCGKKFKRRKSLKVHRRTHTGEKPHSCKECGKQFKRRKNLKVHVQSHTGEIPNLVA
The following text describes a protein:
Function:
Intracellular mono-ADP-ribosyltransferase that plays a role in different processes, such as protein translation and unfolded protein response (UPR), through the mono-ADP-ribosylation of proteins involved in those processes. Acts as an inhibitor of protein translation by catalyzing mono-ADP-ribosylation of ribosomal subunits, such as RPL14 and RPS6, thereby inhibiting polysome assembly and mRNA loading. Mono-ADP-ribosylation of ribosomal subunits is promoted by NMNAT2. Involved in the unfolded protein response (UPR) by ADP-ribosylating and activating EIF2AK3 and ERN1, two important UPR effectors. May also mediate mono-ADP-ribosylation of karyopherin KPNB1 a nuclear import factor. May not modify proteins on arginine or cysteine residues compared to other mono-ADP-ribosyltransferases.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
PGGPGSVGMQQPGQSPAVREAVRASLQSDPVAADLRCSLFVSAAQSYKRDSVLRPFPPRYVSGENKDFDALLADVSSIPSVRDVARLGPGEGEAQLGLVHWVLSSKNFTVKTLQREEFVRIQELAEPEGRCVPAPDFLFELQYCDQVNARFQETRGDRDLIYAFHGSRLENFHSILHNGLHCHLNKTSLFGEGTYLTSDLSLALLYSPHGNGWHESLLGPVLSCIAVCEIIDHPDVKCQVKKKDSERIDRRRARVRNSEGGDVPQKYFVVTNNQLLRVKYLLVYSEKQHRRRHTRQVSWLARHHFAITMCLYLLLLIVIGVFNSPAFQSFWNRLFNERK
The following text describes a protein:
Function:
Transcription activator that binds to the DNA motif 5'-CACGTGG-3' in the promoter of iron (Fe) deficiency-inducible genes as well as of genes involved in iron homeostasis, thus contributing to basal tolerance to iron deficiency, iron uptake from soil and iron transport, particularly during seed maturation and germination. Promotes the accumulation of mugineic acid family phytosiderophores (MAs). Required for ethylene-mediated signaling during iron deficiency responses. Improves growth and yield, especially in calcareous soil with low iron availability. Promotes iron concentration in shoots and grain.
Sequence:
MGHQLPPLTPWTNLDLDLDLDLDLDIDEGTAVAVRDATAANGTSSGSGSGSHKKLSHNAYERDRRKQLNELYLSLRSLLPDADHTKKLSIPTTVCRVLKYIPELQKKVEDLEKRKEELTSANCKPGVILSGGIALAPTVSATCLNDKEIMVQVSLLSTTDAATTTTLPLSKCISVLENEGLRLISSSTFSTFGDKTQAHIPLQARYKHLT
The following text describes a protein:
Function:
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MAHMRSVLRGRLCGMREILRCQKASYTEASRKETHFGFQAVSEEEKRERVYKVFENVAHNYDIMNDAMSLGVHRFWKDWLLQLMKPTPGMQLLDMAGGTGDISFRFINYIRAQREKWIRQELKFQQDLSWPDISKTYQNKEEGSLMGSRAVICDINKEMLKVGLQKSLRLGYSEGLSWVAGDAEELPFGDDKFDVYTIAFGIRNVTHIEQALQEAYRVLKPGGRFLCLEFSHVNNPLLSKIYDVYSFQVIPVLGEVIAKDWKSYQYLVESIRRFPSQEEFKAMIEDAGFSKVNYHNLTSGVVAVHSGFKL
The following text describes a protein:
Function:
Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MAQSSATQSYTCSLSGLSPLPPGDAVVTPSGYICSRKLLLTKLSENGGVDPFDDKGVRALDESSLIELSGGRQPAAVVPPRPPTGTSLPSLLSSLQNEFDAVLLELYDTRRALEETRRELSGALYQNDAAVRVVARVCRERDEVRLRLEGVLKEGVAARDSSSSSGSEVAKRVRDEQDVSTDRSHGGADSSDANPAKKAKVDSSSIPPADLEAMSATWATLSKNRRTIAKLKRTPEEIAAIEGTDGIYAKLMTANNGEDKKVNLHKSNAKAGVLALAHVTGGDGGEYVISGGHDKQAIVYNASTGVIAASLTGASDDVVAVDGMMVDNGLVVVVGSNDGSVRLYSVGEEGELIGAVNVDDSPIVHVAVHPSSTKDEVRILAATKGGSVAVLKYNSEGGIMKVITQLRSEEGAVLSGAAMHPDGLIYAVGSEDGKMVVWDLKTQTCAATLEVFEGKPINSISFSENGYHLATSSSVASIPVLIWDLRKQKIIGTIPPSDEVGRVSSVAFDPTASYLAYSGEECTKVCVVKDWDRVVCTLNKGGKKGKKKSDGLLPGGVVWGGEGFGLGGRGGKVWLCAGCDGEKPVRFWGVE
The following text describes a protein:
Function:
May act as a receptor in regulating T-cell proliferation.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MGSQHLPLAALYLLELLVTSCLGGLKVEVQGLTMRLSGSGSRCQGRLEVSNGTEWYAVHSQSWGQLSLYQVAPRQFLKLCQELQCRDPLLLSSSRYFKEVQFQKLIICHGQLGSFSNCSLNRGRQVDSLALICLEPPRTTAPPTTSPPTTTPEPTAPPRFQLVAEPGGLRCAGVVEFYSGGLGGTIGIEPQNDIKDLGQLICAALQCGSFLKPLPETEEAQTQKPEGQRPLPIRWEIQNPKCTSLEQCFRKVQPWVGGQALGLICSDFQPKVQSRLVGGSDVCEGSVEVRSGKGQKWDTLCDDSWAKGTARWEEVCREQQCGNVSSYRGLDPSEKTLGGFYCPPGILSRCHKLEEKKSHCKRVFVTCQNSSRAGLGAGAVMSIILALLLLAVLLVVCGPLAYKKVVKKFRQKKQRQWIGPTGMNQNMSFHRNHTVTVRSQVENATASHVENEYSQPPRNSQISAYPALEGALHRISTQPDNSSDSDYELHGAQRL
The following text describes a protein:
Function:
Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport (By similarity). Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections (By similarity). Acts as an adapter protein that facilitates the interaction of KIF5A with VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 and the ZFYVE27-KIF5A complex contributes to the transport of these proteins in neurons. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a KIF5A/B-dependent manner.
Subcellular Localization:
Recycling endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, growth cone membrane; Multi-pass membrane protein. Note=Localizes at both dendrites and axons. Localizes to endoplasmic reticulum tubular network.
Sequence:
MQTSDRDLSGPEASPSGMPEVLSECPPAPTKSAAFDLFNLVLSYKRLEIYLEPLKDAGDGVRYLLRWQMPLCSLLTCLGLNILFLTLNEGAWYSMGALMISVPALLGYLQEVCRGQLPESELMRRKYHSIRQEDLQRVRLSRVHLSRPEAVAEVKSFLIQLEAFLARLCYTCESAYRVLHWENPVVSSQFYGALLGMVCMLYLLPLCWVLALLNSTLFLGNGDFFRVVCEYRACLQRRMNPRQEECACESSALQGAGGRGLLDSSPAPTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLEDEEGTPCPAEDELTLQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCAGCAATFSVLKKRRSCSNCGNSFCSRCCSFKVPRSSMGATAPEAQRETVCVCASCNQTLSK
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MKKTKKIVRNLETFLVTEYHIKKALKQNINININSYIYISRWGLGRLFTMGDNKMVMANLLSVIMLMHAIVALSSNVRGLSKNYYMKSCPTAEQIVKNSVNNALQADPTLAAGLIRMLFHDCFIEGCDASILLDSTNDNTAEKDSPGNLSLRGYEIIYDTKQEIENTCPGVVSCADILAMAARDAVFWAGGPFYQIPKGRFDGKRSKIEDTKNLLPPSFNASQLIQAFGQRGFSPKDVVALSGKFLFEILGAWRRILCAKQVISLVETMKLPLTTYMEVFWSMQRLVLQLTFKCPHKYVYEWI
The following text describes a protein:
Function:
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation. Required for histone H3 phosphorylation during segregation of homologous chromosomes in meiosis and mitosis. Required for histone H3 'Ser-10' phosphorylation. Phosphorylates tlk-1 at 'Ser-634', which enhances its activity. Phosphorylates zen-4 at 'Ser-680'. Required for the recruitment of bub-1 to the ring-shaped domain between chromosomes during meiotic anaphase I. Also required for the localization of the condensin I complex subunit smc-4 to mitotic chromosomes. Acts at the spindle midzone and the midbody to prevent cleavage furrow regression upon chromatin obstructions during cytokinesis.
Subcellular Localization:
Cytoplasm, cytoskeleton. Chromosome. Midbody. Cytoplasm, cytoskeleton, spindle. Note=Meiotic and mitotic chromosomes. During each division, relocates to the midbody microtubules. Localizes on chromosomes during metaphase and on the central spindle during anaphase. Localization to homologous chromosomes during segregation is dependent on lab-1.
Sequence:
MENKPPVINLPEKETVNTPQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTMDYLPPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDLIGRLLVVDPKARCTLEQVKEHYWIQGMMEAKIRAEKQQKIEKEASLRNH
The following text describes a protein:
Function:
Mediates the import of L-serine into the cell. Is energized by proton cotransport.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKSTEKLKWNKFDATWMLNLFGTAVGAGVLFLPINAGMGGFWPLVLMAIIVGPMTYFAHRGLAYFVLSSKNPGSDITEVVEEHFGKTAGKLITLLYFFAIFPILLIYGNGITNTVDSFIVNQLGMASPNRVILSFVLIAVLISVMLFNEKVMLKITEWLVYPLVLILFVLSIYLIPEWNSAVLYEFPTVGGFLTTLWLTIPVLVFSFNHSPAISSFTCSQFREYKTFDGAERHISHTEKGASTILLFFVMFFVFSCVLTLTPEELVAAKEQNISILSFLANKFDNPYISYFGPLVAFLAITSSFFGHYMGAREGLEGLYLKMKGEAVNRKKLNYATALFFLLTLWGVAIINPSILGLIESLGGPIIAMILFIMPMYAIRKIPAMKRYSGRFSNVFVTIMGLIAISAVVYGLL
The following text describes a protein:
Function:
Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Secreted into the lumen of the colon following cleavage of the GPI-anchor.
Sequence:
MKGILVAGITAVLVAAVESLSCVQCNSWEKSCVNSIASECPSHANTSCISSSASSSLETPVRLYQNMFCSAENCSEETHITAFTVHVSAEEHFHFVSQCCQGKECSNTSDALDPPLKNVSSNAECPACYESNGTSCHGKPWKCYEEEQCVFLVAELKNDIESKSLVLKGCSNVSNATCQFLSGENKTLGGVIFRKFECANVNSLTPTSAPTTSHNVGSKASLYLLALASLLLRGLLP
The following text describes a protein:
Function:
Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging. Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Note=When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation (By similarity).
Sequence:
MDGFVQEWSNLPRSDNGLHMDQLVGELPTDGGFEPQTRARSNTWPCPRPENFVEPVDELDSTKASNQQLADPQQAMQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVAYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWMLNPDAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGAVGLNDATPSPSSSVSEGLDHFPESPLHSGGFQLSPDFRQRASSNASSCGRLSPIRALDLEPDWGYSVDYQNTTMTQAQAQALDQLTGSMADELKLQNDMLQQQGFSAASGLPTQPPPPYQQQQQQQQQQAQQQSQLPQGYTLNGPVSAPGYNTLQPQAQQQQQQQQQQQQQQQQPQCLLHRSLNCGCLHSTRDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNSILLDAASDNGSLLVQQQQQQQQQQQQQQQQQQQLSSGLEGQCLEALNSEQIDEFNLENFQGGLECNVEELLQQEMIYDGLLDINIPLPAVNTNATNVILTNNSTNNSSSGCNISAGVQLSCSQLQAELQLQQQQQQQQQQQQQQQQQQQQQQQQLLLSNNNNNNNNSLELATQTATRVQYTQPSVVTSPPSWVH
The following text describes a protein:
Function:
Peptide hormone that functions as endogenous ligand for the G-protein-coupled apelin receptor (APLNR/APJ), that plays a role in the regulation of normal cardiovascular function and fluid homeostasis. Functions as a balanced agonist activating both G(i) protein pathway and beta-arrestin pathway of APLNR (By similarity). Downstream G proteins activation, apelin can inhibit cAMP production and activate key intracellular effectors such as ERKs (By similarity). On the other hand, APLNR activation induces beta-arrestin recruitment to the membrane leading to desensitization and internalization of the receptor (By similarity). Required for mesendodermal differentiation, blood vessels formation and heart morphogenesis during early development and for adult cardiovascular homeostasis. Acts as a motogen by promoting mesendodermal cell migration during gastrulation by binding and activating APLNR. Acts as an early embryonic regulator of cellular movement with a role in migration and development of cardiac progenitor cells. May act as a chemoattractant for the activation of angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Positively regulates sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel sprouting. Plays a role in placental vascular development; promotes placental trophoblast invasion and spiral artery remodeling in the uterus (By similarity). Involved in the regulation of maternal cardiovascular homeostasis to prevent gestational hypertension and for potent cardioprotective functions during heart failure. Mediates myocardial contractility in an ERK1/2-dependent manner.
Subcellular Localization:
Secreted. Secreted, extracellular space. Note=Found in blood plasma. Found in serum of pregnant mice, peaking at midgestation; indicating a maternal and zygotic origin of circulating APELA during pregnancy.
Sequence:
MRFQPLFWVFFIFAMSLLFITEEKSVNFPRRRKLYRHNCFRRRCISLHSRVPFP
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSSPAPSSTGGAKEKKPLEQITFRFCSECSNMLYPREAEDENKLLFTCRTCNFSEPATSTCIYRNILNNAAGETAGVTQDVASDPTLPRAIKECPACHHPEAVFFQSQQRTSETGMKLFYVCCDCGNIYQ
The following text describes a protein:
Function:
Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
Sequence:
MQSWYLLYCKRGQLQRAQEHLERQAVSCLTPMITLEKMVRGKRTSVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGAHPAIVPSSVIHQLSIYKPEGVVDPETPYPGDSVIITEGAFEGLKAIFTEPDGETRSMLLLNLLNKEVKQSVKNTGFRKI
The following text describes a protein:
Function:
Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL.
Subcellular Localization:
Secreted.
Sequence:
MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG
The following text describes a protein:
Function:
Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity).
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
LHHQIIPVLSQQQTPTHALQPHHHIPVMAAQQPMQPQQPMMPMPGQPSVTPTQHHQSNLPQPAQQPFQPQVPQQPPHQPIQPQAPAHPMPPMPQPPLPPMFPMQPLPPLLPDLPLEQWPAT
The following text describes a protein:
Function:
Putative odorant or sperm cell receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MERGNDPQNSEILLRFSEEKELQPLLLGLFLLMYLISILRNLLIILAISYDSHLYTLPCASSSPTYTEKIATYKGCIMQMYFCVLFAELYIFLLTVMAYVQFVAVCRPLHYTVIMNSWLCGLWVLVSWITSALYSLIQSLMVVQLSFCAHMEIPHFFYELNQVVQLACSDTFLNDTVMYFAAVLLGGGSLTGILYSDPKIVSSMLGISTAQGKYRTFSTFASQLSVVSLFYCVVLGVYLSSAATHSSYSIAMASVMYTVVTPMLNPFIYSLRNKDINGALKIVFGEKTIKVQLSWSWRSSPECKAQNLRTRGWLCGRVVSLHAPLWRPRVSLVWILGTDMAPLIKPC
The following text describes a protein:
Function:
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. Specifically associates with both 40S subunits and 80S ribosomes.
Sequence:
MSSQFFLKTSQDIELFQSYPTFEQSNTNSKDFPVISSVLSPCGRFLALSTKENVKVFTGPCLDNVLLTMKLSDVYDLHFSPAGNYLSTWERASIQDPNHKNVKVWYLNKPFKKDCVSEDIVPAYEYQAKSQSGWFLQFSKLDNYGLRLFKHDLKIVKLSSANADNFDFQSPFAVLSDDETSQHFTTYLISPAEHPTICTFTPEKGGKPAQLIIWALSEGKITKKIASKTFFKADSCQLKWNPLGNAILCLAITDFDSSNKSYYGENTLYLLSFQGVNGTLGGNSVRVSLTTGPVHDFTWSPTSRQFGVIAGYMPATISFFDLRGNVVHSLPQQAKNTMLFSPSGHYILIAGFGNLQGSVEILDRLDKFKCVSKFDATNTSVCKWSPGGEFIMTATTSPRLRVDNGVKIWHVSGSLVFVKEFKELLKVDWRSPCNYKTLENKDEAFFENHIINNWEPLPDSTTSSLDPKISNKSELQIHSSVQEYISQHPSREASSNGNGSKAKAGGAYKPPHARRTGGGRIVPGVPPGAAKKTIPGLVPGMSANKDANTKNRRRRANKKSSETSPDSTPAPSAPASTNAPTNNKETSPEEKKIRSLLKKLRAIETLKERQAVGDKLEDTQVLKIQTEEKVLKDLEKLGWKDE
The following text describes a protein:
Function:
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (By similarity). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (Probable). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Sequence:
MAKNTLSSRFRKVDIDEYDENKFVDDQLQEEPAEPQGPDEAEVDSLIRQGELLRAFQSALRNSPVNSKNQVAKERTQAIVLKVLTSFKSNEIEKAVNTLDPNGIDLLMKYIYKGFEKPTENSSAILLQWHEKAFVIGGLGSIVRVLTSRKTV
The following text describes a protein:
Function:
Involved in the nuclear retention of improperly spliced pre-mRNAs.
Miscellaneous:
MISCELLANEOUS: Present with 2205 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus membrane; Peripheral membrane protein; Lumenal side. Note=Associated with a subset of nuclear pores opposite to the nucleolus.
Sequence:
MEKDALEVRLKSIRHSLDKNTKLLPGKYRNTLGERLITKWRYKKKSHNGSSMLPEKCKSHVQLYDDLVQESSKHFVGFRLHDLRALLKRICSIQNYTRHVLIEWDVRWVNPLTLASKGWEPYQSASQSQVPFKCCCCHAIMTIPLLKNGDDVADYTMKLNEKIWNSNIIGNHLQKCPWRENQVDLNKEYYLSSQNLIREIERIHTEIDRIVSGSNEFSLKRNSSRIFHYLSEKEIQKLAFFFDCKDYSLVGLLLLGYTKFQKDDLVQCTACFHRASLKKLEYTEFNGHALWCRYYNKELLPTMLLELIGKEDKLITKLGVGERLNKLEAVLQTL
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNLLPNTPLLLQHIYKLLGITQFFSNDSIYSKIFGRLLCLPLYVYYFYTHVTFSISFYHSNLVIILIGRFIQNMINFTYILISLVFFYKRSDKIRSSLITLHKLNLDKNTNSWNKWMRVILVLLFASNILQFPFFGESFGYAFCSCYTGTVFLFETLFLDDIFSLVLIKFKSINQQIPSLQHIDELDNITHHYCLLVDLTNEIINHFAMNLLLTFLFWFGYFVVTIYFALCFVTLKVVWWRSFFSVSAFILYETQWLFMVINSFSQIQIEAEKIGSHVHEIWNQFTTKGKIDRRIRHLELLSIRLFYIKVELTVNGFFNLDWAFCHLIIAALATYSVILIQFLM
The following text describes a protein:
Function:
Involved in the transport of molybdenum into the cell. Part of the binding-protein-dependent transport system ModABCD.
Subcellular Localization:
Cell membrane.
Sequence:
MRTVMKNLVFAFCCILFLSNAAPAAELSLSVAASLKEAINELTAEYGKKKPGITFLKNYGASGALAKQIEQGAPADLFISANREWVDYLQNRKLTDEASRCAFAYNSLVFAGTTKQPVAGMKDLAKLRKIAIGSPGSVPAGEYAMESFKAAGIDKALDGKLVMAKDVREAMKYAELGEVDGAFVYRTDALLLGKQARILFAVPEGLHDRVIYPMALTTTGTGKKEAVEFLRFLQSAEARKVLEKYGFAVK
The following text describes a protein:
Function:
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MKALVINYGVGNLYSISSALKRVGFEVTIDNKPRNDYDLIVFPGVGAFSAVAEFILRYRELFNDLRRSGTNFLGVCLGMQIMFEKGTEGKESNGLGWFKGIVDKINANVKLPHIGWDLVFEVKDSCELTYGLDKKYVYYVHSYVAYPTSGDYVYMKSQYGIEYPALVCDKNVVGTQFHPEKSSNTGKIFLENLKGWIKR
The following text describes a protein:
Function:
FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
Subcellular Localization:
Bacterial flagellum basal body. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MTGTDKAAILLLYLGPEATSKVFEHLDDDEIKKISKSMATLGHVPRNVIQDVVTEYSSLTNPDTGIFSQGEEFVRKILEQTLGPQKAEILLKELQSSSFGDMVDVLANLDAKSIANFLSQEHPQTIAVILAKLRAKQTSEIISMLPQGLQAEVVMRIADVDQVSPEILADIDEVIKRELTAMGGVQRYKVGGVEKVVDMFNHLDRSKEKQILEKLDTLNPPLAEVIRKHLFTFEDIFKLDDRSIQAIMREVSNDTLTLAMKTAPDEIKDKIFRNISSRAAEMIKEDLEVMGPVRLSDVEKGQSEIIKIVRRMEEEGKVVLAGRGGDDVLV
The following text describes a protein:
Function:
Negative regulator of transcription elongation.
Subcellular Localization:
Nucleus.
Sequence:
MTRSSRIRKPSQKAREIAEAALLLSSSKTTPSSSGDQSKNSSNKSARRSSNQTTAATGRNQSSSSSVRAKVKIGRKKGRATINSNGDVDVEEEAAKLGNQRRRTNSKQQPQQPQEEEDDDDDDDHATQPSNSNDTETEEDPDVLYCICLGHDDHTPMIQCEGCENWFHFSCINLDPTEAQKIEAFYCQLCNASGNGITRKIDEENPTTQPEQTPSVALIPNSSNRTSENLPETIPKSEDGTPGDSTAETVPRLPSPQPVDLKHEAAPPVPTSREAVKHETAPSVPTSHEVEKKVLCDSSKDNQPDGPSRSSVESITVQPPQSTKATRRKQRLAEGLSSEGETSDEDFTGEESLRTVDRKRKTPTSVDSRPSTQPRISTSTPSSTTPSTPSTPVLGVEKTRKACIEQFFKLFGPIFSKNLKQDEDAAMRFSEAVELELYESFGELDAKNQKVPRRQYMTKLRSLLFNLKNNPAFLNSLSSLELSPKLIVFMSNEDLQTPEQKALAEQVRQRSLHDSVKTLDPVLEPTTSPQADEPIIGSLPPSKAAENHVAVDQPQSATTTEQTPIELNQSRENPSSPSVPPPAQVPVSQSLEQIPLPDPPSVTQPETSAGPDKPVESSQSSPSAAPSHPENATTKCITPSLLSSFDLEKVFAAIRSVPPPQITVSGSDSTATKSQSAGGEVQKEAKEGDSDDSMDLENTPEREVATGDGSGTVKAEVKEKNLPDDYDPFVVANGVDADLEAILHGDQQPGTQNRPNGEPSSIIKESETQSTGNAQAMPSVWTGNVMTVDVGGFAACAVQVGGRPIGTDGLTWSKLIPTDTMAVAGRLPVKDSTNYLVQSHFAPSRELILLELKPNLNGPPELPSPERVLQHQQNLIEFFTKKGRHAVVAVNEKAKQAVRDIYLVPILRQDPLPEFVQLLDDVSIPESTPRARDMMVAVMVLSKGGAPSAWKSAPTLMNPSTSSSSVSVPTPNHQAQVQVAPPLTSSAQNLVGAAQSLSSSASNHGRSPAPVNSSSYSLPARQPPNPSAPIDPIPLLQSLSSKISSVSSQLAFPLLSQIAPSVSTTTPGPPPGFVPYVQPQQSKLPSVPSSSSTPALNGLDLSKVDVSALQALLSHQQAFKPILSHPQPTAIQPTNLHLAPASASTINQPVHHPSVAPEPRTNTGRHPGLPAPPRPANLPLNPHFAHQAAPSVSDSSSSPPPSVRHPSYPQSQQQQQQQSSGWPTSDHQHHPSSSSSPTAALKRPAPFIHPSREKQHRKGLMRMGDVIRSSPPAPHEDPRRRTSSSASASSLNHHHHPHHHPVPPSSPNSVFLNHHHGPPQNHGHPQNHASGRGSKRHSNEFVAPPRDGGWAGRGRGRKLA