lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid for mycobacteria required for formation of their cell wall.
Miscellaneous:
MISCELLANEOUS: M.tuberculosis PgsA1 has been identified as a promising candidate for drug development because of its vital role in growth and proliferation of the pathogen as well as the differences between eukaryotic and mycobacterial PI biosynthesis pathways.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMAIPGKGDR
The following text describes a protein:
Function:
Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown (By similarity).
Domain:
The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to PYGL.
Sequence:
MALDIAMKFYLRSPLRRDRVECRITQSNEPLRPCIQTTDKTLLSELSNQENKVKKRVSFADSRGLALTMVKVYSDFDDELEIPFNISELIDNIVNLTTVEKEHFVLDFVQPSADYLDFRNRLKADSVCLENCMLKDKALVGTVKVKNLAFQKCVKIRITFDSWQTYTDYDCQYVKDSYGGSDKDTFSFDVSLPDSIQSNARLEFAVCFDCEGRIFWDSNKGLNYRIVRHGHRIPYDPVCVSVDQYGSPRCSYGIFPELPTYSGFDKLGPYY
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MGGDESSPVFHDFLGMSYGGGSLPAARWTKGTGIRRLPGEAEASGSASASVGVSSIGHRLISGSVDLGSEMQGVSNSEVSQHDGTEIAPSGLELGNTTGRKRNHFDSSYMGPMKDAVLPMGSGSLESSNATKMLGKEVINEQLGRANDVEMMSSMQPPIRPTKQIVHQTSHYGIGMYWDNIPSYACKYSTLGGAIISQSAADEGSRTGIRGSGVMNVLGHNRSSQTTEPKSYYHVPRNRATACVSRQMTIFYAGQAHVFDDVHPNKADAIMALAGSSGGSWSTTYSTAMNKAKVLGRDDTQKENVLLSNGGDRNHLLGQVTHTPVADPLSGHTSADHRGGVATRDASLMARAAEPNTEGKWMS
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
Sequence:
MNTGKPQKRAVNGVLLLDKPEGLSSNTALQKARRLFHAEKAGHTGVLDPLATGLLPVCFGEATKFAQYLLDADKAYTATLKLGEASSTGDAEGEIIATARADISLAEFQTACQALTGNIRQVPPMFSALKHEGKPLYEYARKGIVIERKARYITVYAIDIAEFDAPKAVIDVRCSKGTYIRTLSEDIAKHIGTFAHLTALRRTETAGFTIAQSHTLEALANLNETERDSLLLPCDVLVSHFPQTVLNDYAVHMLHCGQRPRFEEDLPSDTPVRVYTENGRFVGLAEYQKEICRLKALRLMNTAASAA
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
LVLFFFQAVFNYMIPDHKADVFNPPHTTNISNTFVSVLFDGLTNRWDAIYFIHIAEHSYTFENTLVFFPLFPLIVKLLTFSLFYPFTFFLSIRNVLQIVAVLINFILFILSALTLYKFGLAVLKNEHLSYRAAQLFCVNPASIFFSAAYSESLFSLLTFAGLLKLQSNKVLHASILFGLSAATRSNGLVNMGFIVYYFLHFHLKAILKFDLSFCHNLLLFFIYIFLCCSWFIFYQLFAYIIYCEVNKSHFKNLITNELRNYGKEKGYFTLGDSPSPPWCKLTVPISYSSIQNSHWNLGFLKYYQVKQLPNFFLASPMLFICFYLVLTYFKNRFYRSVFLEMMPRCLIKKLTNDYELKSKYSLHDVTKKEILVHVCHIFFLTIFALFFMHIQVITRLICSSCPVVYWFLAQKSITQEEKIAIAMWKENINDDQFKNSSVFDVCGKDICKSTVENNHSRYRSTTTIIKKVKVNKQKLNSLHERTKVITDTLTESELINWNESLFNKFFSAYTHIYLFVGVAAFCNFFPWT
The following text describes a protein:
Function:
Transcription factor that plays a role in larval and adult appendage development. Specifies the identity of ventral appendages (including legs and antennae) and suppresses dorsal appendage development. Involved in patterning the distal-proximal limb axis. May control the adhesive properties of cells during limb morphogenesis. Also has a secondary role in the normal patterning of the wing margin.
Subcellular Localization:
Nucleus.
Sequence:
MDAPDAPHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGGNNGGGSNSGSPSHYLPPGHSPTPSSTPVSELSPEFPPTGLSPPTQAPWDQKPHWIDHKPPPQMTPQPPHPAATLHPQTHHHNPPPQMGGYVPQYWYQPETNPSLVTVWPAV
The following text describes a protein:
Function:
Required for visual system development. May transcriptionally regulate genes necessary for optic lobe invagination and Bolwig's nerve formation.
Subcellular Localization:
Nucleus.
Sequence:
MLQHPATDFYDLAAANAAAVLTARHTPPYSPTGLSGSVALHNNNNNNSSTSNNNNSTLDIMAHNGGGAGGGLHLNSSSNGGGGGGVVSGGGSGGRENLPSFGFTQEQVACVCEVLQQAGNIERLGRFLWSLPQCDKLQLNESVLKAKAVVAFHRGQYKELYRLLEHHHFSAQNHAKLQALWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRSVLRDWYSHNPYPSPREKRDLAEATGLTTTQVSNWFKNRRQRDRAAEHKDGSTDKQHLDSSSDSEMEGSMLPSQSAQHQQQQQQQQHSPGNSSGNNNGLHQQQLQHVAAEQGLQHHPHQPHPASNIANVAATKSSGGGGGGGVSAAAAAQMQMPPLTAAVAYSHLHSVMGAMPMTAMYDMGEYQHL
The following text describes a protein:
Function:
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
Subcellular Localization:
Nucleus.
Sequence:
MGGAADLVLKAACDACGKASELYSTACRHATLCNSCAATMARSRARCNVCAAPITNVIREYNVRVDTTAGKALSIAKFNTGVPPFSKMKGAGNKWSLRKDGLTQGRQLTADMREKYYNRKPWILEDDTGEHQYQSQLEASQSATATYYLLIRRGKEFDAVPVGSWYNFSKIAQYKQLTLEEAEEKMNKRRSSATGYERWMMKTATHGAAAFGSDLKDLGDAKGKAADGVQSKKESSNEDGNHSDKGEEDEEEGVAKKAVRGLSTRGVDDEEDGGKEDFDLEDEIEIGDDWEHEETFTDDDEALDIDPEERPDVADTENPTGPDIKQDDDENEQGAGGNLSKSGKELKKLLRRADGQNESDDEDDGDTDEDESPLSVLAPKLEHQFGSEQQENNTAKLTATELAVSTPPAPRSNQKRKSGGDGAKTSNRAAVKKPKAEPEAKTLGVKKEPPSSVEPISKASASAGSDTDTSAITEEEIIRVLRAIAPVRSQDFVPRFKARIRTPEDKKHFHDIVMKYAYSHKTNGVSYLHLRKETTSAITEEEIVRVLGATAPVRSHDFVLRFKDRIRTQEVNPTGFVISFDLKSALKKKVLI
The following text describes a protein:
Function:
Seems to act as an ATP-dependent zinc metallopeptidase.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MHLFSHNSPQFTQIHQSKLQQNLKPSSMASATNTILSSNFFGSRILLSTPTPKTHKPSRTKFIIPQSILNRKPNSSNNFNLQSKATLAALLFSSIATPQALADTDLPPPPQTPLQAELVKQNPSTNSSPFSQSNLLTAPKPQSSDLPEGSQWRYSEFLNAVKKGKVERVRFSKDGGVLQLTATDGRRASVVVPNDPDLIDILAMNGVDISVSEGEATNGLIGFIGNLLFPLLAFGGLFFLFRRSQGGPGGPGGLGGPMDFGRSKSKFQEVPETGVSFADVAGADQAKLELQEVVDFLKNPDKYTALGAKIPKGCLLVGPPGTGKTLLARAVAGEAGVPFFSCAASEFVELFVGVGASRVRDLFEKAKSKAPCIVFIDEIDAVGRQRGAGLGGGNDEREQTINQLLTEMDGFSGNSGVIVLAATNRPDVLDSALLRPGRFDRQVTVDRPDVAGRVRILQVHSRGKALAKDVDFDKIARRTPGFTGADLQNLMNEAAILAARRELKEISKDEIADALERIIAGPEKKNAVVSEEKKKLVAYHEAGHALVGALMPEYDPVAKISIIPRGQAGGLTFFAPSEERLESGLYSRSYLENQMAVALGGRVAEEVIFGKENVTTGASNDFMQVSRVARQMVERFGFSKKIGQVAIGGGGGNPFLGQQMSSQKDYSMATADIVDAEVRELVERAYERATSIITTHIDILHKLSQLLMEKETVDGEEFMSLFIDGKAELYIS
The following text describes a protein:
Function:
FAD-dependent monooxygenase required for the aerobic hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the first hydroxylation step in coenzyme Q (ubiquinone) biosynthesis.
Miscellaneous:
MISCELLANEOUS: Partially complements the C5-hydroxylation defect of S.cerevisiae cells lacking COQ6.
Subcellular Localization:
Cytoplasm.
Sequence:
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVQEPLAANAPPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAHQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLVIGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQASEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFASHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR
The following text describes a protein:
Function:
Has a key role in phospholipid metabolism, and catalyzes the first step of phosphatidylethanolamine and phosphatidylcholine biosynthesis.
Miscellaneous:
MISCELLANEOUS: This protein is produced by a bicistronic gene which also produces the CPT1B protein from a non-overlapping reading frame.
Sequence:
MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLGGAWRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPENADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS
The following text describes a protein:
Function:
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cytoplasm, myofibril, sarcomere. Note=Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin (By similarity). Overexpression in cultured mammalian cells revealed colocalization with cortical actin, stress fibers, and focal adhesion sites, sites of potential interaction between microtubules and the cell cortex (By similarity). In skeletal muscles, costamere localization requires the presence of ANK2.
Sequence:
MASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTIHVVDKYSLGTRLQRPRAGASISTLAGLSLREGEDQKEVKIEPAQAVAEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDLQPVSASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECDEGDPDNINSTAKVVVPPKELILAGKDAAAEYDELAEPQDFQDDPDIVAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPVEEGDQGTEVIWLTQHVELSFGPLLP
The following text describes a protein:
Function:
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
Subcellular Localization:
Cytoplasm.
Sequence:
MVRRFFINEFPSFLKGSILQLSGQQNNHVKTLRLKVGNTIELFDSNGKNGVAKIIEINKNETILQLENLGIESTNSEEINKIDIATSLPKLARAEWMIEKLSEIGISNLILLETEFSKSSPQSSSITNNKLDRFERIVIESSKQSRNNQIMNIIPPVSLNQFLKDRFINQKEGDCKYSHVFIGDPYQGKELPLVLDDIKQEQQQLQQKQPQQPQQPQQQSNKAIIKKPKDILLFIGAEGGFSDRELYNIQSVVSNRNDSQLYLTKMGNNILRMETAAILSSGIVKLNLPFLFNYKNK
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MLFTIKPSFLKPVGFIQTRNLNRLYPKQRIPKRPKIPMGSKIAEVTETTSAYYNPPASSPDVRITPPVFRYDAPPIHQRDTSLSKESMFLPPAVSRKSKSKGKLRFSTHQLSSEDIKSIQDLRTKDPNAWTTGTLSKKFNTTRLLISRVCEAPKERIQKVEENFEAEKLAWGSKKREIRRQRASRQAFRTLERVAQV
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC).
Subcellular Localization:
Nucleus, nuclear pore complex.
Sequence:
MSADGPTTSVPVAPGSRLHFSWGLGSELRLMDVQDPSTQEGGEGGHATQLSWGQVSASNRIIAFGTAEQYAEVQRSRLAGTRDDAHLARVAAYARAVRERLLSLRDAGAGGGGEAEDGGLSALEAALWQLLELFFVDAPRNDGNLGEDFVSWLAVHGDALAALTGQPTLGGRLEELKADGAAADAAPDYWPLLRRLVALGRTGQALELLDCHDAKRAALGGAAGAGALQQPGLRAQLELLDCLHVLLKRLPRLAPSSSSGAAAAAGGAGQGQPQQHQHQQHRRDAAARAYGSLAEFGAARAVWRREAGDIAAAEQLFAAAAAASKRTAEGVRSVLGVLLGEPAALRAATTDWLEAAAAEVVHRAPDGLGAGGVGGGGSSNGGGGVVSANQLGALLAAAQAARGSEGASGLLDLLAELLQALCEADVAGVVTVLSNSGVASAWLMAHSLELIAAYVAAGGAAAGGGGSAAGGAIVPAGGGAAAAGGGGGGGLLSRRLVVSGCDLMEYFRLAWAESLLPVGVLGGGWALALGYLAWCPTHGAAAAEALMEALPVDSRDTRGLEKTLAACRRLGLGAAAAVLCRVAGVDALGRGMLGAGAQWMVRASDPRRTAAALALVGGAVEEALIARMVGGGAVAAGGAASGGSAVASLGGASYRAGALQLPGGDELEALLEWLPGGSSGGVAEDAGEGGATGSSTAGSGGRGLAAFLVDVLRLSRAMGALGAARDSNAPPEDARVTEALSAGRAALLSMARRRTPPRRLCLPLLFYCIPLLEATAGGGRLLSSADMQDLLTWAGECARGGATAPGAAWAVGPDGGLGGGPGPKGLGALAAAAGVPERYAKDVQLALVRAVARSHVMENSGGAGGAAAAGAGAGTGTFGASGLVAGAAGRQVAVGGRL
The following text describes a protein:
Function:
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.
Subcellular Localization:
Secreted, cell wall. Secreted, extracellular space, apoplast.
Sequence:
MAPSSTHNTGFYVLMLVGIVISTMVATCAGSFYQDFDLTWGGDRAKIFNGGQLLSLSLDKVSGSGFKSKKEYLFGRIDMQLKLVAGNSAGTVTAYYLSSQGPTHDEIDFEFLGNLSGDPYILHTNIFTQGKGNREQQFYLWFDPTRNFHTYSIIWKPQHIIFLVDNTPIRVFKNAESLGVPFPKNQPMRIYSSLWNADDWATRGGLVKTDWSKAPFTAYYRNFKATEFSLKSSISNSGAEYEANELDSYSRRRLRWVQKYFMIYNYCSDLKRFPQGLPAECRR
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLVRTAVRNVYGLGTPELYRDAEKEDPKAVLDGVAVAGLVGILRQLGDLAEFAAEVFHGLQEQVMVTSSRSNKLVVRVQKIEAALPPLEKSVLAQQSHLHFAYTAGSNWHARIRSEQNHFIYNDLPRFIMDSYEECHAPPRLHLLDKFDPGGPGSCLKRYSDPTFFKRASVGSDEEYIAKVLKEKKGRKIKKKGSWRRNGEVSRSASMPNYGSRMQFAYRNLDRRPSWVQSFSAYDTTLKSDIDSRHGSGLTDYVSQTSFSIQPEDGKSETVSSTIKMQHNQSFDYSFLEEKSDHTFNDIDKDFSQELTDLVSTSVSWNMKLPDTQESKGSFDSTSQLHLNNTFNHDFPEERREVVYDDIGNIVSEEQADRCTSSITWNDKTGREKQESRESFSSPSQIHHDNLPDCASPVRKGDDEYSDMGNSLTEEQIGRNLLPVALSDKMRTAEVESKEIFYSPLQMNPSASIEDDSPNEKLWVISDEESNNFPQGQVVLSSPFSSSSVKNEQLDLSIQKYDFDESLEALQENLVLDTQVLDIATSENIQQQSSEPEAEIIQRSISYESQFDDIESESDSFMDALNTIESESETDLDCQRKRAMELESSLKTESSLNGTHVNSAELSDRNLSTPIPEAAARNSPENRGFGGKTNLVSADSDPGDFSFSNKVKRKEIPENISSGFDEILSSPQIAGITLKLDSSIDVPSSKRSNFLEASQEEPLVSNHITSSPRNPSSALPVVNKIHCSPSDSEKPPPQLLATPKVKFWTNGGLLGLEPSKPPDGVINSVGQVYESNQNEEVIASRQDPVPSSEKHTGKQDDVQNTSREKADCQNSGQGVAFSIKNISSRFSAKDLDVKLDKSSNLYQQNCTGKPLHSSSNGYGMTSRTIGTVSPESPILAGQENGKNSSRILELGNRLLTNGFHGKLSLGWNDKTDSASSFNTGSNEPINDYQQCVGRTIKDFPGRVSPFTSPPSSPPLGHMKISFQPIDSIETTKLKLRFPESNNDMFPSFQLVPEPSIPLQEVGSDSDDDTFSGSSPDLSDDYLSHQSESNSEQWESGNFPNLKDQEVYNALHRISLTESTSTSFENGRTTHQDLHTCSRNHIPFAESSLEDSPSDNLFDLPVLDTQHSSFKHGVGNTTSARDFLEPLKESTPPAPPLPSMQWQNMQSHLDDEQDDLHLFSEHHHVFDHKEPGSTISHQPKPPPFKQNQVIESAFTLKSKQPQSIDTTGQQFADHAGNGRGINEKEDFLHQIRAKSFNLRRTAPAKPTGNTVPPASVKVNAILEKANAIRQAVGSDDGEDNWSDT
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MLEHFCECYFDLSGPILCPVLGSITPLFIPNSSIRPIRLIGLCVSLITFLYPPVPRIQFDPSTAKSQFVESLRWLPYENIHLYMGIDGLSLFFVILTTFLIPICISVGWSGMRSFGKEYITAFLIREFLMIAVSCMLDPLLFYVLSESVPIPMFIIIGVWGSRQRKIKAAYQFFLYTLLGSVFMLLAILLILLQTGTTDLQILLTTEFSERRQILLWIAFFASFAVKVPMVPVHIWLPEAHVEAPTAGSVILAGILLKLGTYGFLRFSIPMFPEATLCFTPFIYTLSAIAIIYTSLTTLRQIDLKKIIAYSSVAHMNLVTIGMFSPNIQGIGGSILLMLSHGLVSSALFLCVGVLYDRHKTRLVRYYGGLVSTMPNFSTIFFFFTLANMSLPGTSSFIGEFLILVGAFQRNSLVATLAALGMILGAAYSLWLYNRVVSGNLKPDFLYKFSDLNGREVSIFLPFLVGVVRMGVHPKVFPDCMHTSVSNLVQHGKFH
The following text describes a protein:
Function:
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTISVIKVSGHELDDPTFLGGLTAALRGFQQPLVLVHGGGKEISAAVERAGLQIEFVDGLRVTSPAVMDIMQMVVCGTINKRIVTALVNAGVKAIGLSGLDLGLLRCEPYRPAGRDLGRVGEVTAVDGAALLHLLALGWMPVIAPVALGATDGLSYNVNADMVAEAVAGALAGAELVFVSNVPGVLVDGRVVPALTPAAVEELIANGVISGGMIPKVRAALAALQRGASSVRIVNLAGLHDGGTRFTHGELSE
The following text describes a protein:
Function:
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
Subcellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein.
Sequence:
MMNLNAVHILTRRDERCRAEDGRPRSPRTAVPGPSPARLTSVSSLFLGPGPEQSPKRARTPSNSHVGRGEAPPAAARKVPGAPGSGRRRRGCHVGAGRERVNAGPGLESGKMKLKEIDRTAMQAWSPAQQHPIYLATGTSAQQLDASFSTNASLEIFELDLSDPSLDMKSCATFSSAHRYHKLIWGPHSMTAGERVSGVLIAGGENGNVILYDPAKIIAGDTEVIIAQKDKHTGPVRALDVNMFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPLEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHNNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFTSSPLRVLESHTRGILAIAWSMADSELLLSCGKDAKILCSNPNTGEVLYELPTNMQWCFDIQWCPRNPAILSAASFDGRLSIYSIMGGSTDGLRQKHVDQLSSSFGNLDPFGTGQPLPPLQLPQQTAPQSVVLPLKKPPKWIRRPVGASFSFGGKLVTFENAKPQQQPGIDQQPQHHYVYVSQVVTEKEFLARSTQLQEAVQSEGFVSYCQKKVDMAQADFERNVWSFLKVNFEEDSRAKYLELLGYRKDDLKNKITSALNLNKECCADGELGEAPTESDVPLLNKGDEGQTAEEHFLGERAKDSKQETEDLGSERKTFNISVSGDVDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLSRTQEKYFSKIQSKITRLITAVVTKNWKEIVLSCDLQNWREALAAVLTYARPDEFAALCDLLGNRLESEGDSLLRTQACLCYICAGNVEKLVACWSKVQDGNSPLSLQDLIEKVVILRKAVQLTQAVDPNAVGALLAEKMSQYANLLAAQGSIAAALTFLPANTDQPDIVLLRDRLCRAQGELPAGQEAIKAPYERQPMPKDRAGPVAGQVPGPQASAQQYYQQVRIAPTVTTWSNKTPTALPSHPPAGCPSDTQGDKPPPPGFIMPGAINPSAPPQQATSPSYSMYSQAGTRPAYPQTYQTQQYSFGTGETALYQPQQPVAAPASASYPSPASNTNPPYLPAAQPVPSPLYPGQPQPSPTSLNPASSFPPPPSGASFQHGRPGLPATSVAYALPTGPTGPQNGWNDPPALNRAAKKKKVPDNFMPPVPITSPIMNPLADPQAQMQQPPAAPVGTPSFQPQQLSAGQQAPLGPYAPQALGPCVVPPTTFKPRTEGAPGAPIGNAIQHVQALPTEKITKKPIPEEHLILKTTFEALIQRCLLSASDPQTKRKLDDANKRLEFLYDKLREQTLSPAIVSGLHNIVKSIETRNYVEGLNIHMHIVSTSNFSETSAFMPVLKVVLIQANKLGV
The following text describes a protein:
Function:
Required for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide. May assist the glycosyltransferase PgaC in the polymerization of PGA.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNNLIITTRQSPVRLLVDYVATTILWTLFALFIFLFAMDLLTGYYWQSEARSRLQFYFLLAVANAVVLIVWALYNKLRFQKQQHHAAYQYTPQEYAESLAIPDELYQQLQKSHRMSVHFTSQGQIKMVVSEKALVRA
The following text describes a protein:
Function:
Probable transcription factor that binds to the DNA sequence 5'-CAAT[AT]ATTG-3'; Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MDGEDDVPEWMMEVGGAGGKGGKGGGGGALDKNKKRFSEEQIKSLESMFATQTKLEPRQKLQLARELGLQPRQVAIWFQNKRARWKSKQLEREYSALRDDYDALLCSYESLKKEKHALLKQLEKLAEMLHEPRGKYGGNADAGAGDDVRSGVGGMKEEFTDAAGAALYSSEGGGGGKFAHFTDDDVGALFRPSAQPTAAGFTSSSGPPEHQPFQFHSSSCWPSSTTEQTCSSSQWWEFESLSE
The following text describes a protein:
Function:
The main transcriptional regulator of the Salmonella pathogenicity island 1 (SPI1) gene expression. Activates the expression of invasion genes by a direct action at their promoters and also indirectly by increasing the level of InvF. Also binds upstream of prgH and directly activates the expression of prgHIJK operon.
Sequence:
MPHFNPVPVSNKKFVFDDFILNMDGSLLRSEKKVNIPPKEYAVLVILLEAAGEIVSKNTLLDQVWGDAEVNEESLTRCIYALRRILSEDKEHRYIETLYGQGYRFNRPVVVVSPPAPQPTTHTLAILPFQMQDQVQSESLHYSIVKGLSQYAPFGLSVLPVTITKNCRSVKDILELMDQLRPDYYISGQMIPDGNDNIVQIEIVRVKGYHLLHQESIKLIEHQPASLLQNKIANLLLRCIPGLRWDTKQISELNSIDSTMVYLRGKHELNQYTPYSLQQALKLLTQCVNMSPNSIAPYCALAECYLSMAQMGIFDKQNAMIKAKEHAIKATELDHNNPQALGLLGLINTIHSEYIVGSLLFKQANLLSPISADIKYYYGWNLFMAGQLEEALQTINECLKLDPTRAAAGITKLWITYYHTGIDDAIRLGDELRSQHLQDNPILLSMQVMFLSLKGKHELARKLTKEISTQEITGLIAVNLLYAEYCQNSERALPTIREFLESEQRIDNNPGLLPLVLVAHGEAIAEKMWNKFKNEDNIWFKRWKQDPRLIKLR
The following text describes a protein:
Function:
Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
Subcellular Localization:
Vacuole membrane; Single-pass type II membrane protein.
Sequence:
MRPSVITVAVLFVQSTWASFAFGNPMSMRNKAHTNDLVNSKGKPLVGRFLHITDMHPDIYYEKGSTVDHYCHSYDHNSDDTPLGKSKVGYLSPGPGYECDSSPALIDKTLEWLKEHQDDVLGGIDFILWTGDNSRHDNDNHFPRTQSEILASNEDLVNKMIEAFPDVPIVSAIGNNDIYPHNIMEAGPSSMTRQLAGAWDALIPYEERHTFEKGSYYLCDVIPDKLAAISINTLYLSNKNAAVDGCPDDNLDEPGSLFMRWFKIQLEAYRLKGMKVWLLGHIPPTRGQWYEDCYTSFTDLLYEFRDIIVGQLYGHMNINHFVFLEFDKLPVDTESYGIKSAQPKYVKSLIDAQYAELPTFPENLTEEFLNGTVGNYSLATVGGSIIPEMFPTFRVYEYNISDIANQLDDREELTEITSFNWETLEEQSQSDYEIDKKKKKKKKNNKKKKKNKRKNIKPGPLGPAYVPSLFTPISFKQYFLNTSNYMDATKDTEISYELLYTSKDSPYNMPDLTVPEYMRLAKRIATCDKPEDPHQFKLQSGDQNTFRISKKKKPSICPIAYTYLWHAYIGSISDFED
The following text describes a protein:
Function:
Plays an important role in regulating the size of autophagosomes during the formation process.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
SACLIHWIMKLPKLNLLTYCFGEDYYEVLGVSKDASLKQIRKAFKKLALTMHPDKNVNDPEAHNKFIKINGIYEVLKDEDLRKKYDQFGEEGLKENGRGGGRYESYNYYRDEFGIYDDDPDVVTLDGSDFGNADAAVKSGETWFVNFYSPRCSHCHDLAPTWRKFAEELSGAINIGAVNCHDNRWTCNQKGVHSFPSLLIFYHQPIKYMGDRSKKDLMKFVLEHVNIDVVDLWDGNIAEEISSHPKLPWVVSFCGGDAEAHEDEDGEIIGDCPSRNTRMKMAGLLKDIANVGSIDCGTSPELCKRANASKKAGVYYFPLDTFPEPKKNDRIHSFSSLDAREIYSEFMLQLMPSLTKVTVTKLEKLVSRQATLAFFQFDTTNDVDVKETNLKKLPQLLKDHNIDVVKVYCNNTRWCFDNFHISQDAVLVFKGTGIEEYEIHHASKLTTAELSLFAHESVHARVATLNAQHFHENSLKESNQPWFVDFFAPWCPPCRALLPELRKASTSLLNIKFGTVDCTSFSSICEKFKIHSYPTTMLFNQSVVTEYNGQHNSHGILEFVQDLISPPYEHLNPESFKDKVLRRGVGVTWIVDFYAKWCGPCKAMLPAWRQMAKKSIKLLEGVVKVGAVDCAIPTNNQLCKTQGVNAYPEIRLFPSKKKPRSNPLYKVYTDWNRQALAMAGWAIESTNHDVKDMTMEDFDRGQLIDKQAWLLDFYAPWCGPCMAFSPKFILTSFRFVGRVKFGKVNCQQFPSICSQAGVNAYPSVKFYHPVKSDEKRSSVKSITSQDPDEITQLVEQFIQPYKHLIKKKSSQKKKDEL
The following text describes a protein:
Function:
Nuclear genome-encoded factor required for the accumulation of photosystem I (PSI) during plant development.
Subcellular Localization:
Plastid, chloroplast thylakoid lumen.
Sequence:
MAGVGCHFLLSLSPPLYSIRRPAAAHRPAKARSHISCCSRHDDAEACSTSKPLTNGKEEEKTTPSRRKCLACLCAVTLISASGPTMLTPNGLASDMMSKPAVCRNCNGSGAVLCDMCGGTGKWKALNRKRAKDVYLFTECPNCYGRGKLVCPVCLGTGLPNNKGLLRRPDAKKLLDKMYNGKILPDS
The following text describes a protein:
Function:
The H2 subclass of histamine receptors mediates gastric acid secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MISNGTGSSFCLDSPPCRITVSVVLTVLILITIAGNVVVCLAVGLNRRLRSLTNCFIVSLAITDLLLGLLVLPFSAFYQLSCRWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLITPVRVAVSLVLIWVISITLSFLSIHLGWNSRNETSSFNHTIPKCKVQVNLVYGLVDGLVTFYLPLLVMCITYYRIFKIARDQAKRIHHMGSWKAATIGEHKATVTLAAVMGAFIICWFPYFTVFVYRGLKGDDAINEAFEAVVLWLGYANSALNPILYATLNRDFRTAYQQLFRCRPASHNAQETSLRSNSSQLARNQSREPMRQEEKPLKLQVWSGTEVTAPRGATDR
The following text describes a protein:
Function:
The probable reversibility of the MTHFR reaction in plants suggests that they can metabolize the methyl group of 5,10-methylenetetrahydrofolate to serine, sugars and starch.
Sequence:
MKVIEKIQESVKDDRVVFSFEFFPPKTEDGVDNLFERMERMVSHNPSFCDITWGAGGSTADLTLEISNRMQNMVCVETMMHLTCTNMPVEKIDHALETIKSNGIQNVLALRGDPPHGQDKFVQVEGGFACALDLVKHMRAKYGDYFGITVAGYPEAHPDVIPANGLATLETYENELAYLKQKVVDAGADLVVTQLFYDTDNFLKFVSDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTRIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKIMASGIKTLHLYTLNMEKSALAILMNLGLIEESKISRLLPWRRPTNVFRIKEDVRPIFWANRPKSYISRTIGWDEFPHGRWGNAKNPSYGALSDYQFMRARSRDKKLQEEWAIALNSVEDIYERFMYYCLGKLRSCPWSELDGLQAETKIIDDHLGNINSKGFLTINSQPSVNGAKSDAPLVGWGGPGGYVYQKAYLEFFCSREKLNAVIEKCTAYPFLTYMAVNKKGNWMSNFNQIDVNAVTWGVFPSKEIVQPTVVDPASFMVWKDEAFEIWSRGWAQLYPENDPSRTLLEQVQNSYFLVSLVDNDYINGDLFAIFKDIWN
The following text describes a protein:
Function:
Catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MLLVLITIPVLVWFACKRWADAFYSLGSNRLLGVRTPLLLIAHPDDECMFFAPTVLGLLRNELPVSVLCCSTGNYYNQGEIRKNELIRSCAALGIPPSNVTLIDHRDLPDDPKVQWDPHLLSSLILRHIHEKKVDLVITFDEGGVSGHANHVSLYKAIRSLHCAQKLPEGCSVLLLESVNLFRKYLSVLDLPLSWLCPRDVLYVLPEKQYQQAKEAMTCHQSQLLWFRHLYLLFSRYMVINSLRFLLCANEPDTKEKSR