lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Ribosome-binding protein that acts as a regulator of mRNA translation by promoting ribosome inactivation (By similarity). Binds RNA (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm, perinuclear region.
Sequence:
MASLNPFDLLGDDAEDPSQLAVALSQKVEKAAAAVQPPKAAKFPTKPAPPSQAVRESRNAPQGGRGGTGGRGGFSRGRGNGGYNRDNRNNDAPGNENGFSGGYRRPSEDADGASRGGSVGGYRVGGGREGPRRGGVANGESGDVERPPRNYDRHSRTGHGTGMKRNGGGRGNWGTTEDDIPPTSEEPTTEVEKSPVAEKQGGEDETPEAKKELTAEEKAQKEAEEAEAREMTLEEYEKILEEKKKALQATKVEERKVDTKVFESMQQLSNKKNTDEEIFIKLGSDKEKRKDATEKAKKSLSINEFLKPADGKRYNGRGGGSRGRGGRGGRGEGGNQRYAKEAAAPAIGDTAQFPSLG
The following text describes a protein:
Function:
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via promotion of STUB1/CHIP-mediated ubiquitination and degradation of ICER-type isoforms of CREM.
Sequence:
MLWLALGPSHAMENQVLVIRIKIPDGGAVDWTVHSGPQLLFRDVLDVIGQVLPDATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGKRNIHGLKVNTRAGPSHHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKIPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMKKQPKERPAPEDLMGHPFIMQYNDGNAEVVSMWVCRMLEERRTQQGPQ
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Sequence:
MEKEKINILLYGLGAIGSFYAFILHRTNRVRLTVVARSNYEAVIKNGIYIDSANHGQHRFHPDLVIKSPSEVTHPYHYIICANKAIDQDAVAAQLAPAVDNNTTFVIIQNGVGNEEPFRRAFPACSILTCVTWVGATQTSPGVITHIKSEDMQIGLFPNPSVEASVENSRLEEFTSFLAAGGTKFQVVEDMQLPRWEKVVWNAAWNSITALTMVDTQTWLTSSADATPLTRRLMGEVIAVGRGCGVDLDKGLVDRLMDKINALPGIGSSMQVDCRNGKPMEIEVILGVPLRRAKELGIDTPVLETLTCLLRAVDGRFR
The following text describes a protein:
Function:
Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).
Sequence:
MATAASAPVSTATVRVSNIPPSAVAKKLLAFFDSAVAAAGAEYACEIAAARRGWLSRGNGIVQFDSTAAATLAAELASSGRLPRFLGSLLSVSPAPADLLPRAPDHSLRTAGARLLVGNRIAEREFEAADSWDGVRVEVIPGKRRIDLYLDHDSQMYRLEVFFEDIRNCYKCSFNGAGAILLQLIYAPRICTTISGPAVYSRFSDDRFHACKEDVKFTWVRALDFTPNHSFGKCSTLALVLDGAPGNSLMEFVGPSSKVVPLVDCLTGCSVSYEVLFRLNSLVHMGKIVAKHVNAGLFKALEEIPVHISRRIFEKMSKLERAHSRKRSHNALLSSKTEGEGKLMMCYRIHITPSKTYCLGPEEEVSNYVVKHHKKYASDFARVTFVDEDRSKLFPDAISARTGRGFFSQPLKTGLYYRILSILKEGFSIGPKKYEFLAFSASQLCGSSVWMFVSNDSLKAEDIRSWMGHFEEIRSVSNSSRQTVEILPWDVEEIPDIEVTTDGTKHIFSDGIGKISEKFAKDVAYEIGLDPTNPPSAFQISMKKFESKSTMFNITSWSKPQPRYMNREIISLLSTLGISDEIFELMQQDDMRELDEMLTNREAALSVLGKIGSTETKTASKMLLQGYEPSLEPYLLMILKAHQDNRLTDIRTRCKIHVPKGRVLIGCLDETGELKYGQVYIRITKNSKEQKDNGQPYFLKIMGKTKQQLLLEKLQYRKILVSILVTSECLKLSMTMDCMLTTWLIVFPQRGERPHPNECSGGDLDGDLYFITWDEKLIPEKVDSPMDYTAARPRIMDHVITLEEIQKYFVDYMINSLGAISTAHLVHADRHPMKARSPECLQLAALHSMAVDFAKSGAPAEMPQSLRPREYPDFMERWDKPMYISNGALGKLYRAAASRMQSSPAPSFAQPNPVFDPDLEVPGFEEFLESAEECYDLYTEKLSALMGHYGVEHEDKILTGNIRNRLLYLKKDNKRYFEMKDRIIDSVEGLHKEARGWFTSCPKAEAPRRASAWYRVSYHPDHRRREKKRFWSFPWIICDELLKIKESNNGDDPLQSHLSVENIH
The following text describes a protein:
Function:
Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system.
Miscellaneous:
MISCELLANEOUS: Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHSSQTDNITLG
The following text describes a protein:
Function:
Confers broad-spectrum resistance to pathogens.
Subcellular Localization:
Secreted.
Sequence:
MENKFFAAFFLLLVLFSSQEIIGGEGRTCQSKSHHFKYMCTSNHNCAIVCRNEGFSGGRCHGFHRRCYCTRLC
The following text describes a protein:
Function:
Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro (By similarity).
Subcellular Localization:
Cytoplasm. Midbody. Chromosome, centromere, kinetochore. Note=Detected in the intercellular bridges that connect male germ cell daughter cells after cell division.
Domain:
The protein kinase domain is predicted to be catalytically inactive; The GPPX3Y motif mediates interaction with CEP55.
Sequence:
MSRAVHLPVPCPVQLGSLRNDSLEAQLHEYVKQGNYVKVKRILKKGIYVDAVNSLGQTALFIAALLGLTKLVDVLVDYGADPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLHDEKGRNPQTWALAAGKERSTVMVEFMQRCAAHMQAIIQGFSDLLKKIDSPQRLISGVPRFGGLMQGNPNGSPNRPPKAGVISAQNIYSFGFGKFYLTGGTQLAYLGSLPVIGEKEVIQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELHLSTHPHCSRLRMADLLIAEQEHSSKLRHPHVLQLMAVCLSPDLEKTRLVYERVTVGTLFSVLHERRAQFPVLHMEVIVHLLLQISDALRYLHSRGFIHRSLSSYAIHIVSTGEARLTNLEYMMESQDGGAHRGLTRVPLPTQLYNWAAPEVIIQKAATVKSDIYSFSVIVQEILTDNIPWDGLDGSVIKETIVLGNYLEADVRLPKPYYDIVKSGLQVKQKDRTMNLQDIRYIMKNDLKDFIGAQRTQPTESPRVQRYEFHPDVNVCLGLTSEHPKETPNLEIKELKETGSQFHSPRGHSSPTGKATPEPPVPDVSPVAQQTHRQDAASPACSVAEEARNPSPDQTSLCSFEINEIYSGCLDTADDPEEECPGTGSSLEGAIPNQTDELKSMEEELEKMEREVCCSCDEDESSSDADTELSCEDWEWQNDALCSPSRPEPARGAKGATNNRSMTEEYISKCVLNLKISQTLIHQNADLLRNVQQKIEKLEMIQKEQAERRSLWASSREFAGIHDSPSALGPPASSYLPPVVQRPGDQQLDPGGSGLTLARSPRTLPTLCGPGKQSRGEQFQPTHGAKASLERDRNQNTSSQGRPRESSPQSKTTQLSSALLTVPSHPQGSPTSSKPGQDSTRISMQSVSSEIYNAKSRNNKDDGEIHLKWKTEVKEMAAKAATGQLTVPPWHPRSGVALDSEAENEPDPLPQLPIRVSEHMDWQQAADYLKKSDEPGGNDKCGQTDSSDQRGRQSGPQRFTSIRHLPPREDEQPEHSEVFQANSDASVAVEKSYSGQSAQSTCSPESSEDTEDMTDEFLTPDHEYFYSSIAQENLALETSSPIDEDFEGIQHACARPQASGEEKFQMRKNLGKNSEILTKSQFQPIRSPEGEQDETLKEPPKEVKEKDISLTDIQDLSSISCEHDGSFKEVSCKTPKINHAPTSVSTPLSPGSLSSVASQYKDCLESIPFQDTKTGSTSCGTSQESTQTLSDKFTSVREKAKSLDSLLTSSEVLPARLTNLKRLPAFTGAGSSSIAKAPDTSRCATQRRSLPKELVEAISQHHIDELPPPSQELLDEIEHLKGQQVSSTALDENTASRPGSTENDQRHLEEQETHSNKEDSSMLWTKETQDLEEDTERAHSTLDEDLERWLQPPEDSTQLPDLPKGPAREASSKDQEVGEKKRKGEESTKPEKRKPESFLGTSEEEELKPCFWKRLGWSEPSRIIVLDQSDLSD
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Sequence:
MFYRDDDQSWSGGAFQGGAFRDDRERYWRESNPDPYPDPNPSQLQQPDQVVSQQQIPNQPPQQIPQQVQNPNQFPQQVQNQNPNQPQVQNQNQNQQQVQSQNQNQQQAQNQNQNQQQAQNQNQVVRGFYDQSCPSAESVVRRTMVDSFRRNPLLAAGILRLFFHDCFVRGCDGSVLLDRKPGGPIPEKESDVNNNSITGFRVIDDAKKRLERMCPGVVSCSDILALAARDAVWISGGPRWSVPTGRLDGRVSLATEADNEIPPPDLRIRDLRKAFLAKGLNTHDVVTLSGYSFTGAHTIGRAHCPAFEDRLYNFSATNAPDPTVNLSLLDSLQKICPRVGNTTFTVSLDRQTQVLFDNSYYVQILASNGLLQTDQQLLFDASTAGLVRAYAADSSMFFRAFAKAMIKLSRVGLKAPGEGEIRKHCRRVNP
The following text describes a protein:
Function:
Cilium-specific protein required for cilia structures.
Subcellular Localization:
Cell projection, cilium. Nucleus.
Sequence:
MGDADRAMNEPEAAKTVSGIQVIPAEDVASIEDIITIDPDCYELDLNHRRIEKLENFEPLTRIERLFLRWNLIKKIENLSSLKTLIELELYDNQITKIENLDDLPHLEVLDISFNRLTKIENLDKLVKLEKVYFVSNRITQIENLDMLTNLTMLELGDNKLKKIENIEMLVNLRQLFLGKNKIAKIENLDTLVNLEILSLQANRIVKIETLEKLANLRELYVSENGVETIENLSENTKLETLDLAKNRLKGIANLEKLELLEELWLNHNGVDDWKDIELLKVNKALQTIYLEYNPLAKDVRYRSKLRDILPQLQKIDATLCKVPGT
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MAGLAPQGSQYDARHYDSKIIEVLGAKGQDFFTSYDEVYDSFDAMGLKENLLRGFEKPSPIQQRGILPLCEGFDVIQQAQQGTGKTATFCSGILQQLDYDLVECQALILTPTRELAQQIGFSSRIYWCPGRVFDMLRRQSLCSDNIKMFVLDEADEMLSRGLTDQMYDIFQLLPAKIQVRVFSATMLPEALEITRKVAITQSVIFVNTRRKVDRLTDKMQSHDHTLSATHGYMIKTEGTLSCRTFALVPLVCSLLLTSWHVVLMSSKSHLLSIMISRHSQRTASIELTVVDGLGGRVLLSTLSPRMMKECFLDIQKFYHVVIEELASNVADLL
The following text describes a protein:
Function:
Lysine-specific endoprotease. Involved in corneal virulence.
Subcellular Localization:
Secreted. Note=Experiments performed in E.coli.
Sequence:
MHKRTYLNACLVLALAAGASQALAAPGASEMAGDVAVLQASPASTGHARFANPNAAISAAGIHFAAPPARRVARAAPLAPKPGTPLQVGVGLKTATPEIDLTTLEWIDTPDGRHTARFPISAAGAASLRAAIRLETHSGSLPDDVLLHFAGAGKEIFEASGKDLSVNRPYWSPVIEGDTLTVELVLPANLQPGDLRLSVPQVSYFADSLYKAGYRDGFGASGSCEVDAVCATQSGTRAYDNATAAVAKMVFTSSADGGSYICTGTLLNNGNSPKRQLFWSAAHCIEDQATAATLQTIWFYNTTQCYGDASTINQSVTVLTGGANILHRDAKRDTLLLELKRTPPAGVFYQGWSATPIANGSLGHDIHHPRGDAKKYSQGNVSAVGVTYDGHTALTRVDWPSAVVEGGSSGSGLLTVAGDGSYQLRGGLYGGPSYCGAPTSQRNDYFSDFSGVYSQISRYFAP
The following text describes a protein:
Function:
Essential for actinomyosin ring assembly during cytokinesis. Has a role, in conjunction with F-actin, in assembling myosin II-containing proteins, such as myo2, at the division site.
Subcellular Localization:
Cytoplasm. Note=Associated with the actinomyosin ring.
Sequence:
MTHELSSTPQIDLLNDILKNSVESNVFSDYQKKQIVTLILKSKISTAIVLLSPKSTAASEWNYLCNLQDLHECVLCVDTILPANLQTIAKRIFSLVLLPPLNDWCKQLRDAFLRFVSQPSICPTDFPLKLFFLSTVGIELLIVNEKIIPQKTQKYLLYELFSSPSSITANEIARLCQEANNRNYLLQSLTSATDARRAFLNNPNYRLLSAIIFQDGPSNLAFVLAKDCVLLARQPETIPVSFERMSSLLLMCLPSHPDFISPEFCHEWTELAERNGLQEEWLNILNTACNFKECRAIIHKECSEFIKDNHTSRVAILISMKLAFQYQLSQVIPTLKLLLQSKVYDSVLLEALRQSSTLGPVKQLIADDSCLLNNLSKLLLDTNISPLDASSIATIIYNMCKFKITKSEHERELNQLRNMAEASKTIDYKEDETAPTERRIQKILEYDILSKLFSAAKHYNSLNGLLAMILVHMANYKLARRKLVQIGALKFLTRQCFIQTQDSNAAFALAKILISVAPHSIFTKAFPSNRAIHPMSKLLSTNSADTEYPILLGKFEVLLALTNLASHDEESRQAIVQECWRELDELIIETNPLIQRATTELINNLSLSPYCLIKFIGDKDSDFENTRLHIVLALSDTEDTPTRLAACGILVQITSVDEGCKKILSLQNDFNYIVRMLTDQDEGIQHRGLVCICNIVYSKDQEIFNKFIKTPKAVETLRTYITKQAALKELQHEALVMIDSRLQGSK
The following text describes a protein:
Function:
Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex. UAF seems to stimulate basal transcription to a fully activated level.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MSNPPTRPTLYNLVNADGELSYRARDLVQDFSVPIPHELPDPDLVHSIQDFATEYMLATGKKSFECLDESALLGLGYLVTEWMDAMVTDCLEEFEER
The following text describes a protein:
Function:
Involved in proteolytic processing of BAG6.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MVQSAVEVLLPSAWEIEVAVVASVFLIASYWLFAYRGGGDDDVVGVGFDRSRLMQNLDSGDAFDKDKIGHLRGDTQTNAAYIVKVELLAAKNLIGANLNGTSDPYAIVNCGSEKRFSSMVPGSRNPMWGEEFNFPTDELPAKINVTIHDWDIIWKSTVLGSVTINVEREGQTGPVWHSLDSPSGQVCLNINAIKLPVNAPRAVTGYAGAGRRRVTLDQQGPTIVHQKPGPLQTIFDLLPDEVVEHSYSCALERSFLYHGRMYVSAWHICFHSNVFSKQMKVVVPLGDIDEIRRSQHALINPAITIILRMGAGGHGVPPLGTPDGRVRYKFASFWNRNHTLKALQRAVNNYHAMLEVEKKERAQSALRAHSSSVKGGGKVQVKAPEDTAAVPVKFQAFIKEEVLVNIYNDVFASTPEQVLNVLLADDSTYTNEYRSARKDKNLNIEPWHTAEEYDGQVREIKFRSICNSPMCPPDTAVTEWQHVVLSPDKKVLVFETVQQPHDVPFGSYFEVHCRWRLEAKDETSSVIDIRVGVHFKKWCLMQSKIKAGAIDEYKKEVEVMLEVALSYLKSHSSSSSHGDIDKSALSSPTPENIS
The following text describes a protein:
Function:
Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHAVQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDFICTSLIAVILTIKLFLLINQFEKQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAGKDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKITTFDNRPLYVPNSLFSSISVENPGRMTNRRITTTIGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLVYFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSHGADFAFPSQTLYMDNITPPEQGR
The following text describes a protein:
Function:
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MRGSSNKKIDPRIHYLVPKHEVLNIDEAYKILKELGIRPEQLPWIRASDPVARSINAKPGDIIRIIRKSQLYGEVVSYRYVISG
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endoreduplication (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSEMASDEEENIIPFQLQFDKPIPFQIKIAEWNPEKDLLAMVTEDSKILLHRFNWQRLWTISPGKPVTSLCWRPDGKAIAVGLEDGTISLHDVENGKLLRNLKPHDVAVVCLNWEEDGQSNTDESGNFSVYEDRTSRFFPPAPRPPKMPGLVAGDSSFMDDGEDSLAELSNTSFRKFNILCTGDRDGNICFSIFGIFQIGKINIHELSLPVPHLDEHASCKLFNASIYKVALSKDLCRLVVMCTGELKDCDIKPREEKINVQDLPGLHCLAMDTSIFWKRKYELHQVAQQASNIEDLTEVIRASLSVMNKQWADAMKTFHEKFHSLSTLIIDNGLESSPQEEFLSLLGGARISPALNQFLVNSLGEVGVKRVLKSVCGTGKELQQVVLDHLQPAAEIIGFRIGELRGLSRWRARYQGIGLDEMLLNEATENTGLLLVQVQRFMMVLSSVVQQFSNFFNWLVRSIKYLMQEPNDQLLSYNSELLVVFLKFLYDQDPVKDLLELSEAGDDIEIDLKTIGRVKELLQFGGFSECDFLQRTLAKEFQHMESSFKMAFQMPFTTISRKISCMKLLPLCPLQLSTTQTPTTIPMSLSFYKNELSDDTPCQSGYTDYISFQVPDETFPEISNCIGIAKGYKQNSNNEKNGYTSLEAVLLSVPNGYTCVDLSLYKDKELVLLLNKTNTDSEGSGEACMMVVQTGDLAFISISGSSSLNQWELEDLKGSIVNLEMENEKVRKVPHSVIAPLAVSASRGVACVFAERRRALVYILEEDEDEEISDEK
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Subcellular Localization:
Cytoplasm.
Sequence:
MKIGIIGGGSVGLLCAYYLSLYHDVTVVTRRQEQAAAIQSEGIRLYKGGEEFRADCSADTSINSDFDLLVVTVKQHQLQSVFSSLERIGKTNILFLQNGMGHIHDLKDWHVGHSIYVGIVEHGAVRKSDTAVDHTGLGAIKWSAFDDAEPDRLNILFQHNHSDFPIYYETDWYRLLTGKLIVNACINPLTALLQVKNGELLTTPAYLAFMKLVFQEACRILKLENEEKAWERVQAVCGQTKENRSSMLVDVIGGRQTEADAIIGYLLKEASLQGLDAVHLEFLYGSIKALERNTNKVF
The following text describes a protein:
Function:
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Dispensable for SPC enzymatic activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDWKDPRLTEQILQYTLISSALIAIAAGYLTASLKTMFLVYGGCVFVTLLVIVPDWPYFCRHPREWMTPKRADAPFHHQQQRSSPGLESIRESALDASKRD
The following text describes a protein:
Function:
Polynucleotide 5'-kinase involved in rRNA processing.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSSNKKRRIDEKPMSALSALQARRREAAASPVQTTQTGSESDEKSVTTSVNPYQLLRKDSSQSTAPKTPKKNVVKDQYLPRGAESPASRSRGVVIASGNTDTLNPELAGASQKVVREYSSFRLSKQNHRVKTGGVVELNLSNSERFLVLGSFGIRVIQGEVSLAGATLYPSETIEWVHAPHCHAVPMLRTIDETILELHPDRNARGIRQLGRLSPLFRKIWNESPETNSSKTSKESTFEIIYTSEDAPKKCIIQKLVSPPEWNKKLSSLVATSRKKPSLSTLICGPKSAGKSTFSRLFLNGLLTDRSQKQGARSVVILDLDPGQPEYAPPGTLSLVFVTKPNLGTPFTHPSLKNSAFTVVRSHSMASATPAPNPDLYLACATDLFDTYSKHYSGAPLIVNTPGWIQGTGLDLLSSLIEKIKPQEVLYMSEAGPDEAVNALRAATKLMFTELPSQPSEFTSRTAAHLRAMQTMSYFHLQNTALKTSNLLDTSTRLKWDASPLSSRAPLLVQYSSSKRGVLGLLSYDYQCSPELLADTVNGLVLAAVEIEDRKAFSNFPQEVAPPPLVSTSPENIPFIPNYDDVALDPRYSRTIGLVLLRGIDTKSETLQLVTPIPLEEFRSIKSQGRSIVLLHGKFDTPNWAYTEELYERAGTEEGNDMVLEVTEEDTEDDQSGVEPEGADGVSDLTEVPWVEVLKGSQRRPVGSQVWRPLRHLGRNNTGD
The following text describes a protein:
Function:
Activates the diguanylate cyclase TpbB/YfiN by sequestering YfiR at the outer membrane, which counteracts the YfiR-mediated repression of TpbB/YfiN at the inner membrane and leads to increased c-di-GMP production. May act as a sensor of envelope stress; Part of the YfiB-TpbB-YfiR (or yfiBNR) system, encoding a tripartite signaling module that modulates intracellular c-di-GMP levels. The system is a key regulator of the small colony variant (SCV) phenotype, and plays an important role in biofilm formation and in vivo persistence. The c-di-GMP produced by TpbB/YfiN stimulates the production of the Pel and Psl exopolysaccharides, which promotes surface attachment, generates an SCV phenotype and confers resistance against phagocytosis.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Domain:
Dimerizes via its N-terminal region.
Sequence:
MLPQRLHPSRLLALALFSLVLGLAGCQTKPPQTGLSAEQIAVLQEQGFELRDEGWEFGMSSKVLFGNNLDRLNPDSRNTLTKIARALLAVDIDKVRLEGHTDNYGDEGYNQKLSERRAESVAAVFREAGMPAANIEVRGLGMSKPVADNKTRAGRSENRRVAIIVPAE
The following text describes a protein:
Function:
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Sequence:
MKSDCIQTTTCQERKKDPMEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVRSVKARDSEFTTNQGPYKPRMIDPGVRSAFLRALSSHLDSRLDSCLTASSLVRFQTIFQSAQSDLPKMWAMAEGYGACLINKPELVQDMVKQVRNQVENPRFSVSIKIRIHDDLTRTVDLCRKAEATGVSWITVHGRTVEERHQPVHYEAIKIIKDNASIPVIANGDIRSLKEAENVRHITGTDGVMVARGLLANPAMFAGYEETPLKCVSDWVDIALELGTPYICFHQHLMYMMEKITSRQEKRVFNALSSTSAVLDYLRDHYGI
The following text describes a protein:
Function:
GTPase-activating protein for RHO1. Must be involved in the normal assembly or function or both of actin. Plays an essential role only at low temperatures.
Miscellaneous:
MISCELLANEOUS: Present with 1420 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPNNTLKQGSKIENVSPSKGHVPSFWKQFINNPKSMSSENITVPRSPTSLSRNAQPTTLKRPPLSSRPYSYNTPTKDRKSFSKSAKQNNNNNNANSGTSPHAEFKNYRDMFLSNRNGFTGRVFGVTLAESLSVASAEVIVQSELVSFGRIPIVVAKCGAYLKANGLETSGIFRIAGNGKRVKALQYIFSSPPDYGTKFNDWETYTVHDVASLLRRYLNNLAEPLIPLSLYEQFRNPLRSRPRILRHMLTHEVSHPNANKTNNVTVKSSRQNYNDDGANDGDIEKEDAKDDEEKRRRKIRHKRRLTRDIRAAIKEYEELFVTLSNDTKQLTIYLLDLLSLFARQSQFNLMSGRNLAAIFQPSILSHPQHDMDPKEYELSRLVVEFLIEYSYKLLPHLLKLAKREQQERLSTENKKNNGDKQKTDPIEIPKITSSDSPPIVSSNKNPPAIDNNNKLDHTTLSPISTSIPENSSDLQTSKMLKPPKQRRPHSKSFGSTPVPPDVIASNKRRTSLFPWLHKPGILSDTGDNGDLTATEAEGDDYEEENVDPYGQSPSSVHSGSLPKQHYLPIPRMNRSLSGNSTNSSFNTRPISMILTSGNDNSADQLELLSNTHSNNERSNALPLTEDDGDERNSRSRKRESWFQRLTSRSGSANRA
The following text describes a protein:
Function:
Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
Sequence:
MTSRPGAPPEEQGRGGAEMVRAALSPPFLLPLLLLSWAPRSQAAADKDEIQCLPGLAKQPSFRQYSGYLRGSGSKHLHYWFVESQKDPKSSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGATLEYNPYSWNLIANVLYLESPAGVGFSYSDDKSYATNDTEVAQSNYEALKDFFRLFPEYKDNELFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDPDCVTSLQEVSHIVSSSGLNIYNLYAPCAGGVPSHLKYEKDTIVVPDLGNIFTRLPLKRIWHQTLLRSEGRANLDPPCTNTTAASTYLNNPYVRKALHIPEQLPQWDMCNFLVNIQYRRLYQSMYSQYLKLLTPQKYRILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVDYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPQAALTMFSRFLNKQPY
The following text describes a protein:
Function:
Protein kinase essential for cell division. Plays a key role in initiation of septum formation and cytokinesis.
Sequence:
MHNIQASSITLGDCLGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDIKGANILTTKDGTIKLADFGVATKINALEDHSVVGSPYWMAPEVIELVGATTASDIWSVGCTVIELLDGNPPYYDLDPTSALFRMVKDEHPPLPSNISSAAKSFLMQCFQKDPNLRIKTRKLLKHPWVIMNQTSSKFSDAIDEVQKYNERVKESTLTAIIEPTSNRINPTLHSGRQSSYHMPESPKTPIAESPDHDNWDNEFQGTLKISDDVLKKSEHFMDFCSNFKGKNNSSSITSSPSKSRHAFNSDQISESNNFNASPLSTPLKAQFDPSKPALNRSIDHQKTPQHKRYLSTEFKENIPDGIEKFVETPRDSEFTDIFPTSSIKVQGLRKETGLGTLVLNKCYGSWNNEENEDGEESDIFDSIETNLENLDIENNIALDKRTHLASLLSSLLGSLRDKNIGSKDTTVSQIASILSEDLSLKREIIQAHGILPLLETLREIKTPDVQLLLLKLINTVAFDDHTTLQKVCFAGGLPLMLSFSNREHSFEFRYESAIFIQQMYRTSALTLQMFLSSNGLNSLLLFIKEDYGTNRDFVFVGVEGIWKLLRQQDYIPKNDICTMVVNDSLEPLTKAMLKALATDDDSSRMSLTRICEILLALSQADNYVKESLLCESALRRILRILLYLPHSDMAITLQFFKQLSMVPSSLSLLRKVHIIPLLTHILGDSKIEKGRKEIRSEALAALFNVCKLDKKSQEEAVISGAIPLLQEVIIKDRLFKEFALPILLALPQAGPVSRIYLWQNKCLDFFLSLLSDLNWQSAVFDTIASWLQFELREVQRVLAEKRNVQLVLKVFCISQSASSNRMLDTLGRVCQISPRLAASYGQPIIFQKFKEKLTHKGTKPIVVLNIFQIMKSMCEASSQSVAYIAHCGLPDVVANLNQTSDSVLVKELAKDLLKYLKVPQGPINEHKSPISKPHMPPPRWQPKQPLTQ
The following text describes a protein:
Function:
Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
Sequence:
MEREFNYTPAHFNHARTILYRLAGIKLADSKDALVYSRLVRRIRQLKLAGFSEYFTYLAECESEHQEFINALTTNQTAFFREHHHFDILKQYLQTHPQTRRIWCAASSTGEEPYSIAMSVAEHFGTFQTPIEIIASDIDSVVLSKAEKGIYPIDRLSAVSDIRKKRFFHRGIGAQQGNVRVIPELRQMLQFTRINLLDESWPISTPIDVIFCRNVMIYFDRVTQEVILKHMMSTLTPTGLYIAGHSENFAMFPDIVTACGRTTYKPTKRNASGKTKS
The following text describes a protein:
Function:
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MSLQMLRSRVALARPTLVRPSVGQMTKRFAGTAPVPLTWERFLLLRTRRRQINFVASIFTGVATSVLAWGFISEAELDLEQQDVFFGLDAFTAAGLGVVAAGFMGSLLGPTIGQLIFKATNSKQWPAFLMKETDFLSHIQKNRVNPRYQSVSNPVPDYYGEKIGSLKDYRRWLRDCAKYNRAREV
The following text describes a protein:
Function:
TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.
Subcellular Localization:
Nucleus.
Sequence:
MDPSIVKLLEDDEDESMHSGADVEAFQAALNRDIGGDTSTSQLSGSDTGSNNSLSQSLPKWPTSSHDNQSDCHNQEPKVVQHQEQRHSSEMEQKPQQPLVEQLHNVASKDAINLPSSQKQSQDESVQGHTVQAPHQNSQTNGIQNSEKDPVFNHEAVNTHNSNHGSQYAKLQQMSNQQATVNEQPGSQVNRNKQVPFAMLLPMLIPQLPKDRAMQLQTLFNKLKKDEMPKDQFVRLMKGIVGDQMLRLALTKVQLQTRSNPGPAGQQHPPVRMPNVNSGATKFNDPHALAQLHQRSMNAAADQSNNTSSAVQVKNEPTYPTMEINAKKSQKLDVQVESEGVQLNQLPSSSSNAVSQEMERSSLHLQGLNKEQQQHLHFPSAYGSSGGNYNPFSGSTSSSTSSLRPQPLDSHMRQIPHQSISPNQLGGTTQGLIGLTKLDQQNSFNDPKRMPGGFVSPMVNNTASQLTTNSWQPSANKEQNSASFSSVPYVKKEPNDLSTEQQHRHNVSNQGTLKEEFSRGLPASTSMLHTTSSSLLPLNSSSPSVSQLDPSATLSSQIPSNTSVINARTPLKKPSPGQKKPIEALGSSPPPPSKKQKVSGASLEPSIEQLNDVTAVSGVDLREEEEQLFSGPKEDSRASEAFRRVVQEEEERLILQKAPLQRKLIEIITECGLKSMSDDLERCLSLCVEERMRGVISNVIRMSKQRVDLEKTRHRTVVTSDVRQQILTMNRKAREEWEKKQAETEKLRKLNDVDCNAGIDGDKEKDEGRTKAMKVNKEVDDKMRTNAANVAARAAVGGDDMLSKWQLMAEQARQKKRGGGMDASSGSQPAKDVSHRSSSTSGRSTKDNQAREKKGPTSGAGRKFGRSHATTPQTSIARSISVKDVIAVLEREPQMSKSSLLYRLYERIHSDTSTE