lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Acts as a component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis- Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. COG3 is also involved in actin cytoskeleton organization.
Miscellaneous:
MISCELLANEOUS: Present with 4140 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MARSRKNSLVRDIASHPTIPESQTIVGLLDDSYLFDKLKKLSLAVENSDSLQRTDVSEGCSEVNGSEATTSADVKKTNKYLYYTTYLDQLNIKIDEYKVVLDQTRQVNDQLDSSIKKFRKISQDTGAFIEETKTIYEKQSKLSNLTESIPKALHYFEVLDPIMRRLNHATSPAIVKKSSFTTMLATIDESLRFLDENSDLKDAAAYRIKFKQCLIRACELISHFLTNLLKQTNQEILDKTKNKNSLTGLPSTTRDAFLYSKFYTIADTFKIQVSEIVKRSNEKAYNKYHDELNSILYECFNHYFQTRLRLLTPVIWSHIDEIVVKDKDQGLVKFIQDGKVYFQQLCADEYKLFVEFFPEKECRFKINQWFLQLCEPLYDSIRVRVLKETDICTLCDSVTLFAPYYEFEEGSEEYVKQFTDIQYDKLFEPIVQKVQARLILRVQIYVQQNILSYRPTRDVFMISNRRRKSKTSLQGGNEDATTSDDNPDPLLESYLSSFKNRSILPISPNDADDKSIDSEESTDKISQLQTYYPPLLKTLALLSKIYEMINSVVFDDLAHHVVHDCIVSLRNAYDMVIKSSAGKSDFNNLDISLAYLKNLLMLRDSIQNFNIQYTVNETYLDFSGVEGFFKSLKENGRNVLKKTKSSSILTLARELVPKVVNNMVDARTELISELRNVIKDFTESTSLELIDDTLDINSDEDLLSKNVKLRENIKARLPRIYEQILNYIDDQEIVTNLLDAVQELITQSYSKYYETITELAENGKFAKDQVADVMYLDVFTDFFAKEVADLLRNGDIDTITK
The following text describes a protein:
Function:
Protein of unknown function; part of the gene cluster that mediates the biosynthesis of siderophore ferrichrome A which is contributing to organismal virulence.
Sequence:
MTIDLSLKSNQQKTIAVLGASYAGHRAIQVLVASLPEDWRVVVLERNTHANHLYAFPRMSVVRGHEQKVFIPYTNMFKPALDRRDQHVLLHANVLELDQEQRRVSYELIDDKQSGVQWLHWDFLVYALGSHLPDPINVWSNSEHVNTHDGSKMMGVKWLRDAQDRIEKAESIVIVGGGALGVQLATDIAVTYGSSKKVTLTHSRPQLLPRFDPWMHEKTAARLQELGVELALGSRVDLSTVSEDKKRFKLLDGRELQGDLTLFCLGQTPNTSLLGASSLNDSGMAKVEPTLQLSANERIFVIGDAADAFGAINAGHTAWDQAEVAAKNILALIDNKGQAMKLEEYKPTPPAIKVSLGIDRAIRQTMAGELVEVDSGSIDLNSTNMWTRRGLSTDDLWQ
The following text describes a protein:
Function:
Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol (By similarity). Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity). Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting (By similarity).
Subcellular Localization:
Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. Mitochondrion membrane; Single-pass type II membrane protein.
Sequence:
MDLDVVNMFVIAGGTLALPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVRHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSMVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIDGQVKRIHQFVECLKLNKKPFHLVGTSMGGHVAGVYAAHYPSDVCSLSLVCPAGLQYSTDNKFVQRLKELQESAAVEKIPLIPTTPKEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNTFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIANSQVELLENCGHSVVMERPRKTAKLLVDFLASVHSTDNSKKLD
The following text describes a protein:
Function:
Binds the lower part of the 30S subunit head.
Sequence:
MSSAKSMPIYKKFVQEGIVKYKLHEFMEKISDKAGFHGVEISSTPIRDIITVYVESPGVMIGRGGRTSKRISDILKEELGIQNPYIQAKKVDKPFLSTRIVASYIARRIAKGERYKKVAYSALGRVMAEGAKGVEIRLSGKFGSQRAREERFREGVIYRCGQDYIENVEYAVKHVLMPQGMIGVRVRIVKPGVRGPDAVVIKEDEIERIRERIKSEMESLSESEVVEIPEELEGELEVAGEVKEDESEQAR
The following text describes a protein:
Function:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Sequence:
MSEEIKSVTRFLKESPPGEYEDVVAALKGFVENTEIIDEGIKATKEDWLIHNCSTIEIDDHKAILCEEARRGKNKFIDPVTNKVFTYDFENQTIVTPEPQPAAKGEEPQPVEEETLESSSLREAIQPLALAFAKSTVHNGTCGTYDSKNGVKIVVRASTINKANFRTGIILMHFTCAEGNLKGSIELKGHFYEKGNCIGTQVSEFEDTYQGDDDGAKAEDIVKKLSKFFIKWNNALTQGFELLNSEGLNKLRRRLPINAQKINWQQELRGLGAMQK
The following text describes a protein:
Function:
Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.
Sequence:
MTDTFPAALVGPSSKERKYDRQLRLWAASGQQALEESRVLLVNSDGSWGDQGTGVSGVAGVETLKNLVLPGIGGFTIVDPAVVTEPDLGVNFFLESESLGKSRAEETCRLLRELNPDVEGSFRPKSISEVLQQEPDFLAQHRLVLISGPVKRSTLDTVCNAAKALNIPVLYLRSVGFYSVFSLQLPADFPIVETHPDPEATQDLRLLNPWPELAAAGASISNLDSMDDHQHGHVPYVLLLLHYLEKWKQAHDGKVPSNYKEKSEFREFVRASARTNNAEGGEENYDEAVAAVLKSLNPFSLRGSIREIFEMDQCKNLKQNSAEFWLIAAAVHEFYQTHKVLPLPGSLPDMKAQSADYVSLQNIYKSKARKDVEEVTATVRRLEAQLGPRAAVIPDKDIEIFCKNAAHIKVIHGRDIPRINGDAQTLKAITDNLSSSEALVPIFIACQILDDIVTDIQESNIADVSLDDESLWNTHIQQVISNLASDPTAIDERAREKILEATQELRRTEGGELHNISALTGGLVAQEALKVITRQYVPLDNTCIFDGVRSRSEMYRL
The following text describes a protein:
Function:
Secreted effector that acts as an elicitor of hypersensitive response (HR) specifically on plants carrying both defense protein RPP1 from several ecotypes including RPP1-NdA, RPP1-WsB, RPP1-EstA and RPP1-ZdrA.
Miscellaneous:
MISCELLANEOUS: The ATR1 effector protein of Hyaloperonospora arabidopsidis is a polymorphic member of the RXLR class of secreted effectors. The ATR1 alleles are differentially recognized by RPP1 genes from different Arabidopsis ecotypes (Niederzenz, Wassilewskija, Estland and Zdarec).
Subcellular Localization:
Secreted. Host cytoplasm.
Domain:
The RxLR-dEER motif acts to carry the protein into the host cell cytoplasm through binding to cell surface phosphatidylinositol-3-phosphate (PIP). However ATR1 does not bind to PIPs, even though it harbors the RxLR-dEER motif at the N-terminus, suggesting that the RxLR-dEER motif is insufficient for PIP binding; The tandem repeated WY domains are involved in the recognition of the RPP1 defense proteins of the different Arabidopsis thaliana ecotypes.
Sequence:
MRVCYFVLVPSVALAVIATESSETSGTIVHVFPLRDVADHRNDALINRALRAQTALDDDEERWPFGPSAVEALIETIDRHGRVSLNDEAKMKKVVRTWKKLIERDDLIGEIGKHYFEAPGPLHDTYDEALATRLVTTYSDRGVARAILHTRPSDPLSKKAGQAHRLEEAVASLWKGRGYTSDNVVSSIATGHDVDFFAPTAFTFLVKCVESEDDANNAIFEYFGSNPSRYFSAVLHAMEKPDADSRVLESSKKWMFQCYAQKQFPTPVFERTLAAYQSEDYAIRGARNHYEKLSLSQIEELVEEYSRIYSV
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MTHDDEKPMVGSYRPKSRRCCVATVLSVSLVVVLVICIAIPLGMRSGKDDGNGDPAACVATDYPDTCRESLAGSDGTPVGMSKASIKSSDEQVGQLSDGTTNEQCKELLTSARELFARVYASMDITNQTLREQTCADIQTQLSAALTNVNTCKDVLEESGSPEFASFLERSSKSEQCIGNTLAIVNGFCMYGNEIKNWAGLATGLSMPDLGSFLGNGAHRRLMNVEYSTNEAQEENLLPNWMDSATSRHLLTLPPSYNVIVAKDGSGKYKTVGEAIQRASTSGATRYVIYVKAGVYDEQIIIPKKLAKLTIIGDGIDKTIFTGKRNVGLMKGMTTYLSATMIVQGEGFIGKMFTCRNTAGAAGHQAVATRVTADKVAFYRVKFDSFQDTLYCHSLRQFYRECIVMGTVDFIFGNANAVFQNCQIVAKKTTLQGQQNTYTAQGRSDKHQNTGLAFQDCNFDGTPDLKRNVQYYPTFLGRPWKAYSVCVLLRPSIQAHVDPKGWLPWNTTDFGLYTSFFAEYKGSGPGSNRRYRVKWSHGISDSKTANKYQAASFIDGKSWITDLGMPYSNAAV
The following text describes a protein:
Function:
S-layer protein. The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of the cell.
Subcellular Localization:
Secreted, cell wall, S-layer. Cell membrane.
Sequence:
MKRFAALSLAALMLLTVFASAASAVDVIEIRGPVYNGSDIDDIIDTYGDGTILTMDATDFAAFYYDIDDNVTTETLSIEDVPDTEGNVIGEGGLIYETTIQEVEYEYYNPDAGWDNYSLMGFFAEKYIPINPDKADKLSKLILDSDDKYTIRTGEMLDLGEGYAIEAKQVDVDGEKVWLEFTKDGEFVDDEIISVSTADDEANTWDVELDDIEDEDDVIVLKVHVNQVFQGAVDSIAQIEGLWLIDYANAMTIESDDEFGNLDDVSIDGDTLTITNEDTFTLTRDDEEEIGEGLYFATADTPSNVLRFYAMKEITDPGTYEIRGQVASGFGDQSWDASSFAGFYYDIDDNVSTETLTVSDLDGNVIPEGGLVYTTTIADVDFEYYNPDAGWDQYPVMGFFAEEYIPINPDKADKIAKLVLDSDDKYTIRTGEMLDLGEGYAIEAKQVDVDGEKVWLEFTKDGEFVDDEIISVSTADDEANTWDVELDDIEDEDDVVVLKVHVNQVFQGAVDSIAQIEGLWLIDYANAMTIESDDEFGNLDDVSIDGDTLKISNEDTFTLTRDSEEEIGEGMYFMIADTSSSDLRYYPYVEKTIGEEVSGEEETPEETPTGEVTETEGEEETPTEVTETPTEGEPAPEETETTESEGTTPGFGFMFGLVGLLAVVYLVRRNN
The following text describes a protein:
Function:
Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation.
Subcellular Localization:
Mitochondrion.
Sequence:
MAVYVGMLRVARLCARSPRVLGARVGLSRVWQEARLWGVRPLSSGELDHTVPLPVGGFSYVQGHVGLHLSNKTVGRCLDATAQRVPDQEALVVHHENIRLTFAQLKEEVDKAASGLLSIGLRKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYALKKVGCKALVFPKQFKTQQYYNILKQICPEVEKAQPGALKSQRLPDLTTVISVDAHLPGTLLLDEVVAAGSQEQNLTRLRHTQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNANMIGQRLRLHQKTPEESRVVLPSPLYHCLGSVGGTMVSLMHGVTLILCSPVFEGKKTLEAISRERGCFLYGTPTMFVDVLNQPDFSSYDISTMRGGVIAGSPAPPELIRAIINKLNMKELVVAYGTTENSPVTFMNFTEDTVEQKAESVGRVMPHTEAQIVNTETGTLTELNTPGELCIRGYCVMLGYWGEPQKTEEAIGQDKWYRTGDIAMMDEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPQVQEVQVVGVKDDRMGEEICACIRLKEGEKTTAEEIKAFCKGKISHFKIPRYIVFVTNYPLTVSGKIQKFKLREQMEQHLNL
The following text describes a protein:
Function:
By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
Subcellular Localization:
Cytoplasm. Early endosome.
Sequence:
MFAVAHDYSSFSSSSCPCCALPQLRAGPGSPTGQLHCSLCLPPATSSPTGELALTRSSSLGEFSWSQRKLVTVEKQDNGTFGFEIQTYRLQNHNTYPSEMCTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTHKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQVLKQTLKKKWVEFRSLQLQEHRLLHGDATNCPSLENMDIDESTLFGSLPGLGPALLDRNRLSSESSCKSWLSSMTLDSEDGYQTCISEDSSREAFSRQTSTDDECFVPKDGDDFLKRSSSRRNRSISTASSGSMSPLWEGNFSSMFGTLPRKSRRGSVRKQLLKFIPGLHRAVEEEESRF
The following text describes a protein:
Function:
Involved in silencing within the mating-type region, at the telomeres, and according to PubMed:12867036 also within centromeric DNA regions. Required for the localization of swi6 to the telomeres, silent mating type region, and according to PubMed:12867036 to the centromeric DNA regions. According to PubMed:15545655 not required for the localization of swi6 to centromeric foci. Deacetylates histone H3 on 'Lys-9' and 'Lys-16' of histone H4. This has a direct role in heterochromatin assembly.
Subcellular Localization:
Nucleus. Chromosome, centromere. Chromosome, telomere. Note=Nuclear throughout the cell cycle. Binds to centromeres, telomeric sites and sites between the silent mating-type loci.
Sequence:
MASNPLDNNMPTTPVEEKIPVASYSPSSSGSSSGASLLVDIMCGSKETEDEEVDSDEWDKPETENISDLDERSEMVRYLRASGYAKFLEKYLIEEELPVRSILKKLGINLPSALEEFEDIDLLPLLKEVLKREVARRIKLPHFNTFEDVVNLLKKAKNVVVLVGAGISTSLGILDFRSDNGFYARLARHGLSEPSEMFDIHTFRENPEIFYTFARDLLPETNHYSPSHAFIRLLEKKNKLSTLFTQNIDNLEKKTGLSDNKIIQCHGSFATATCIKCKHKVDGSELYEDIRNQRVSYCNECGKPPLKLRRVGQNKKEKHYFSDGDSESSEDDLAQPGIMKPDITFFGEALPDSFFNKVGSGELEETDLLICIGTSLKVAPVSELISVIPPTTPQIYISRTPVRHTQFDVNFLSPYCDWVIVEICKRAGWLNELQALCDLPECHSGSKTRAFETDLDIKFEEPSTYHITSTTNGSC
The following text describes a protein:
Function:
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
Sequence:
MQKIKGAFPVLITPMDEFQEINWDGVKQNVNYFIEQKVAGIIINGSTGEFVSLSKEERFKMVETVLKEIDGRIPVIVGTAAETTKETIEYTKHAEAHGADCALIINSYYCKPKEEEIYFHFKEISNSVNIPIMLYNNPFTSGVDMSTELMLRIGKECENVTHIKESSGDIRKVRDLVRQSEGAFQVFCGSEDLVMESYLVGASGWVSVAGNIVPGLVTKMYEHFQNGELEKAWEINDAILPLCEFLEGSGKYVQIVKRSMELHGQAGGPSRYPRLGLTADEDQKLQMILSNIAAHAAV
The following text describes a protein:
Function:
Orphan G protein-coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function (By similarity). Couples with the heterotrimeric G protein complex of the G(i) subfamily, consisting of GNAI1, GNB1 and GNG2, thereby acting through a G(i)-mediated pathway (By similarity). Plays a role in the attenuation of D1 dopamine receptor (D1R)-mediated cAMP response in ciliated cells (By similarity). In non-ciliated cells, involved in the inhibition of the beta-2 adrenergic receptor (B2AR) response (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell projection, cilium membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Note=Localized to cilia in ciliated cells; whereas in non-ciliated cells, distributed throughout the cell membrane (By similarity). During cortical lamination, subcellular location shifts, on the day of birth, from expression at the plasma membrane and in the cytoplasm to the nuclei of neurons. This intranuclear localization remains throughout adulthood.
Sequence:
MTNSSSTSTSTTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPAGSAEPPGDWDSGGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQVLYQRRHTAGMLALSWALALGLVLLLPPWAPKPGAEPPQVHYPALLAAGALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPAAPHAPGAGGAAHPAQPQPLPAALQPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGVGDAAAAAAAATAVPAMSQAQLGTRAAGQHW
The following text describes a protein:
Function:
Efficiently inhibits forskolin-induced production of cAMP. Acts as a potent negative regulator of gonadotropin synthesis and secretion. Induces secretion of prolactin; Efficiently inhibits forskolin-induced production of cAMP. Blocks morphine-induced analgesia.
Subcellular Localization:
Secreted.
Sequence:
MDTILVRRLTILTITTSVLVISNSLCVDESMMTNLLSRENVDAEYSKPREAQERMQRSLNVEELRDWGPKNSGFMKLNSAANRAPNSLNNLPLRFGRTFQGERSIKPFVNLPLRFGRHFESGIPRHLPNLPQRFGRTTASGVSKAFSNLAQKLEKPFPPYLLRYSTTRQPWTFRRPQHRNFRNQNFNSYLGKKSGGGELSQENLESRILT
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLCRHHIRSAHALADPELRRAADIDDSEALLEAVAMSGLVGFLRQLGDLAQFAAEMFHDLHEEVLATAARGHNLVSRVQQLEAEVPALEKVFLSQTHHSSFFTKGGIEWHPNLRSEQNLVTRGDLPRFIMDSYEECRGPPRLFLLDKFDVAGAGACLKRYTDPSFFIVESASSGKVTVEVQREKKIHKVKQKKGTRLRNGETPEVVPSHAKLHQLLLQERIENACGDPARLVKLKKKQLNGSAVEAKTWKSYMEKILEIPSPDHKMVCETSIPQPGKLVSDDSSESGIKILEISSITPMNRSLGNENTWSSPNEQELEVNSYAEMDREMDGYIVEVNEQISGGVTEEMSSDYLKVLDEAGLVFDEQNKREFNLDSYHSDDVISEVDDYMDALATIESELDTDNECGPTKKLLNIQNLTDSNGKGEPQLRAQFSDSQSFGDSLTSAEEISSFEQDRNGEHNEVQGQLSDSLSTGTSWASDDNSPFRRDISEEHSQLQQFSDFQYIRNSTSRIEDMSSDQLPPTFEFQRTYCREFVVDDDEHAQGEVISDSRPVSSGSCLMDSEHLMLYSDLGAASPVSLSAGTGRQSDETPSGPVELHLRIEDDEEKKCLVESIVARSDACYPIRDDAFPVVSFDNNSLNNLDVCDPYVHSNDLLQTSNELNLAHEGESGGHSGIEVFQAESLNECSSEILVSGDVGLQGEDPICPSMEVDLNPDTKLLLDVQNLKSEDDIIATQLNSEDLFPVAETTSKSSITQELCFDFTSGNKPDLAEVEFLPPDHQVNFEEVPRILPGDEISGSTCSLDLVEDDVHIKHSSSDIISSPMSNLTKLEETLSIFADPCEKEMIVSEADSRESLTELAAQKVVDQPEITSIDVQLSMSRSVPCDPSDSGIRNNMQHSSIKEKIHYSSSINGLKTVPVCSELDTQRLSGQGINPTKRVMNPLKPLIPDFLPKASKNSLEEMPPMPPLPPMQWRTGKVQHASLFTQREDIEVNLASLQPIQPNKLDDKSQFGLPTSEKETLPYQNLFLPVMAVESNIHQYSSGFSVGMSEQPVSIPFQFPVMVNEANGQYNFLVPEQSQIQNPFLTLQDRSPLGYAVALEGEINPSPCPPSLLAECVVSRADPILQQEKPTQSPSELTEGTSLEVTKDRPGELHLVLPAECPDSGDDPISPKEKPTQSPSQLMEETSLEVKTLEQSSINLEREQEDPSTSPMSPPSLEIKETNHSLLPSEGEMAFPLDTSSQTSKRDNTETPNGKPKNKRPLPQEDPVIDPVAALDKSRLRKVTERVMPPRAPKEDGRESLLEMIRSKSFNLRPAAVQRPPRIQGPKRT
The following text describes a protein:
Function:
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
YRVLWKQNKIVSVLYFILCAFCMTVDGGLVVNCSAQNYPNTSCLIPPTTATLDLSHNNIEKIEEQDFTEVKGLRKLYLQFNQISFIDHRAFEDNPELEYLDISNNYLLEGSVLPFKNLVALNYLDISNNIGDKIQLGPQVSLLKHLQVLKLGNPQIISLGKNIFQGLGSLHLKEFHLITGDLDEYEHSLKILYGLEKLTLEVNIWHDLELLQHMFQDIKNATRTLQLKNADLVRGGTFVSLFSTFDDSELRSIAFQNISMNDEFVTSLFNTVGKANLEEISFDLIHFDAIGHWKVDITHFQDIHLRRLFIRHIYNPNFYRFTSLEFMVEFFKPLIEVSIVNASVFYIPCAIADVMQSLEFLEVSYNLLHEYTLFPNCHRPLPGLRSLVVDRNNFGDLKKLAAMTSHMEQLVNVSAAFNTLDFSSKEPCPWTPTIKFLNLRGNHLSSNVFMCLPNSIEILDLSLNNITIIANLEKMQYLTQLYLSGNNILSIDHLPPLTYLTILHVDKNKINAVDIATLKALNLTELKLSYNPFDCYCNINNLCEYFVGSLTRIEEWPEGYKCEIPLSLRGSEICLQDLSFVQCNPGMLAGVVVACVAVLVALCICICIRYNGPWYIKTIWIWIRAKKAPDIDLGERNLEYHAFLSYSEQDSTWVMNNLLKQLESDDPPYRICIHERDFTPGKAIIANIIDCISKSYKTVFVLSKNFVQSEWCHYEFFLAQHRVFEERRDSLILLLLEPIPANSIPDRFCKLRKMMNKSTYLEWPPDEACQSMFWKRLKAVLNLEVK
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
Sequence:
MPRRREVPKRDVLPDPKFGSVELTKFMNVLMIDGKKSVAERIVYGALEQIEKKTGKVAIEVFNEAIANAKPIVEVKSRRVGGANYQVPVEVRPSRRLALAMRWVRDAARKRGEKSMDLRLAGELIDASEGRGGALKKREEVHRMAEANKAFSHFRF
The following text describes a protein:
Function:
Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MSLPTSLDQSPKHWWCSQKEEYSWLGFSYHVGGCPSRAVMTNTFGWMRLSKKARYVRLYGGCDHDGFDDDVIEAAAEAGVGIYALIWFGFDNDDKWKGRKARLLHAIKENPKAPYVIRTVTCGSEPLYDKVLPVLKLVAQIEDLKNQLEPFGIPVTLSEMPAGYKANNDTPEIFKAVDFVCLHSFAFFEGNATTADHAQVAIRNDVEYGLKHGRGKKVVITQTGWPSNTKSWKANSPDAIADIAQEKRYFEVLDEHCDYFKANRISWFAHIYNETTLAGWGIYYGNGTEKFHFNPRTSC
The following text describes a protein:
Function:
Binds the promoter region of at least fabA and fabB, but probably not yqfA. Represses the transcription of fabA and fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
Miscellaneous:
MISCELLANEOUS: Probably part of the fabR-yijD operon.
Subcellular Localization:
Cytoplasm.
Sequence:
MFILWYSASSTFGKDSDIVMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE
The following text describes a protein:
Function:
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
Sequence:
MILKRVTEALEAYKNGEMLIVMDDEDRENEGDLVLAGIFSTPEKINFMATHARGLICVSLTKDLAKKFELPPMVSVNDSNHETAFTVSIDAKEARTGISAFERHLTIELLCKDTTKPSDFVRPGHIFPLIAKDGGVLARTGHTEASVDLCKLAGLKPVSVICEIMKEDGSMARRGDKFLSDFALKHNLKTLYVSDLISYRLENESLLKMFCQEEREFLKHQTQCYTFLDHQQKNHYAFKFKGAKTHDLAPLVRFHPIKEDFDFLTTDAFEVFFKALEYLKHEGGYLIFMNTHSKENNVVKDFGIGALVLKNLGIKDFRLLSSCEDRQYKALSGFGLKLVETISL
The following text describes a protein:
Function:
Involved in vacuolar transport and vacuole pH homeostasis. Also required for cytokinesis (By similarity).
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MVTIEALPLRPIEGEQQALHVGAHSSASDPRRTMVTNTSESPLASRQATLTTSTRQKHTSYRLNTAFFLFGLLNNSLYVVILTAALELLPQGVPTGLVSFANIFPALIAKAIWPYFLRGQVRYSKRVWSCAALSFIGMLLVSFFPALAMRLVGISLASFSSGLGELTFLQLSTRYAPKSSETRSGLTAAQAAGAGLETSFAGDAVGWFASGTGAAGLIGAAAWWVVRPLGVQTGMAILSVLPAFMIMAYAIILPSVQELLEGKDGKGGAMYAPLSTEDDAVERSSSDDQPTTANDDRQDSTIHIGPGSEQDVKVRLSFQEKMALLKPMLQPYIIPLVIVYAMEYTINQGIAPTLIYPLPTRSSHPLLSHIIRKLTDYYPLYQLVYQTFVFLSRSSISIFKLPAIPRHLLWLPAVLQTGLLAVLLTESLYAWFRESIASPLVIVLICVEGLAGGSAYVSVFYSIGVDEQGRGIALPSTGEEVDDEGQEEDSAYTMAKKAQEHEFRIGCVGFGDSLGILAASLISMPLQVSLCDAQVRSGRDLCKQT
The following text describes a protein:
Function:
Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 acetylation (H3K14ac), critical for DNA damage checkpoint activation; May also function as a sugar alcohol (polyol) phosphatase that prevents accumulation of toxic levels of polyol phosphates, which can impair glycolysis by inhibiting glucose-6-phosphate isomerase.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAQKKQLYVFSDFDGTITLQDSNDYLTDNFGMGNANRVNLNQQVLDGSISFRDAFAKMLDSVHLSYDEALEVLKKNVAIDPSFKPFYEWCKSQDIRVIILSSGMEPFIRALFEQYLGKEEASSIEIVSNDINVHPDGQWNIVYHDDSHFGHDKSLTIRPYAQLPESKRPHMVYCGDGVSDLSAAKETEHLFAKKGRDLIKYCEREKISFSEFETFADIHKDLQKLFFSS
The following text describes a protein:
Function:
Protects DRG1 from proteolytic degradation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPPKKQQQPAGSSKKADQKKKEKIIEDKTFGLKNKKGAKQQKFFKAVTHLVKFGQQYPRQAAQTESEKKLKKEDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLSLERKCEKRSVYIDARDEDLEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKYFLDAIENNKYGWFWVCPGGGDNCMYRHALPPGFVLKKDKKKEEKQDEISLEDLIEKERAALGPNVTKITLECFIAWKRRKRQEKIDKAEQDMERRKADFKAGKALVISGREVFEFRPELVDADDEEADDTRYTQGTGEDDEVEDPVCVNDVDLSLYVPKAVDETGITVASPERFSTYASIEKDDNKLSEASGGEINSSEQNDLEDRDGDEELENGVMDAVPVDENLFTGEDLDELEEELNTLDLEE
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MEAFKQFCSTYPVIQLVEVTVLISCSFPTVLLLFTIQRAPFHANCKILITLWTLAQSILYMSSLKFIYRMLQYEDNYAPKSFLSPPERHDYMRLQLSVATVAGFCELGITLERAASVRNPGVYHNNSPARLVIGVYLLFAILCGAKLGWMMGEGAESSSALIAAGILNCIDLFSFGSNIGVMLYCRRQYARLFAKTSLNARYQVREANDVAHAMISAYISGMCFKILIAALTWLFTFGFEKTGLYFLNESCWIIVRFPAISVSKRLFQLQHLNAGCGAAMFVLKHDRIRIRLAAFLLRRFFKFAKYKQKSPGITSRHIVTWRSILSNAKRTLEVNIGKFTMPDLMPPINSLYAGRSVFITGGTGFVGKVVIEKFLRDVPDIDQIFVLFRPGKNATAAQRWAHFSKALIFNRVRAENPKSLEKVVPVDGDISLDNFGMSEAHLKLVLENTSVVLHCAATVRFNEPLRQAIDLNLKGTDRMIKLCKKMPKLECFLHCSTCYVNADKEGAIEEKLYEPACDPHKLIEASEWMSEEMLEGITSSVTKKYFNTYTFTKHITEELVRRDCSSLPTLIFRPAVCASIWKDGIPGWADAFQGMTANAAGFGTGTIPRKPANPANVLDGVPVDAVSSMMIACAAYRMHLAAKGDRSSLPIFHCSTSDLNPMTVQHYQNLCGTFLTTYPLEKIILSPSVGTRGSPELEDTFHAIKQHFLGPALDVAVGLLGRKPEFAKAFTKARQMFNVSQFSTKSWTFQSRGMLELLNRMQPKDRETFDFDVRKLDWNEFISDVLFGMKHFLSKNDIFSDEKLEAARKNVKVMQALELAASLLFPYLVTVLATGDFKSWKTALPLGLALYYYFHCNQYSQLLLGLLSCLLVVFGAAADDVAVGAAVAADAGDEAAAHPVDLPTAAGPVIDYHWCGRRDGVICGVRASCLRDKNDNEVNVKDDKVTFPEGRSTLVFMAVSDAREWTVENDRTVGLCIWPLLADTWIVKMNGFEPHGPHAIWLQTRKRNHPRAWREGSGETFMEFVLTTGIYDTLASNGFEKFKDLLSRTLHCKGHSKLYAAMPGQTAKPAKSVMCMKDPTSPPGTVRWIYEIKYSNGRDRCQVRENYSQIFFLDFLLATSKAIGDCFLVATWCTETDYQGEQGPEFKREDGSGKCPKNKWLINNEHYYTGLAECKNSLTQTNNASWIVKIGGKDVEMTMAECTEDQKLPMEKIECNLKKGIWTNYANLTMELNRDANVYFETDKVEAKLRMDAKTLRGISYGAIGVVILVLIIFAVKEIAS
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
TEPPSFPLLEQLDGMPVTLEDVAVYLSREEWRQLDPAQRNLYRDVMQEKNGLTLGEEPFACGFYAGSGFSSFLEPFLDACLGGLYSLGSTFMLTVSPDSSCECQRKTQKPNICQDKGSRGPPAYSFSQKTYTCQKCGKDFSWHSHLVTHQRIHTGEKPYTCIDCGKCFSRSSHLIQHQIIHTGEKPFTCPVCWKSFSHHSTLIQHQSIHTGEKPYVCDRCAKCFTRRSDLVTHQGTHTGAKPHRCPECNKCFTQSSALVTHQRTHTGVKPYPCPECGKHFSQRSNLIAHQRTHTGEKPYSCSDCGKSFSHSSHLTAHQRTHRGVQPYPCPLCGKNFSRRSNLLRHQKIHTGPKALAVLCVQCSPGSAPLTLHHFLEVVPVSMEFLHFIIPFCTILFHHQHIPQFRSYEYFIQVFCPLSLWGTDPAVLWLDQRVDILLLPFGHSSKLPSRMVGSIHNSTSNELVSLLCHIPSSIHYFPLLLC
The following text describes a protein:
Function:
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Subcellular Localization:
Cytoplasm.
Sequence:
MLEGIFDINHVFDEEGIKTLKRFGWDGSVAVQNHNEYSEEKINTAVEYGENCEFKVYSGVKISTKNQNEMEKAVKKYRNKVDILLVEGGDVKINRRVLEMNDVDILSTPELNRMDNGLDHILARLGSTNRVAVELNFGNLLKSKNYDRSKILWAFQRNLKLSKKYDTPVVISSGANDIYGIKAPGDLRGFLNTVADPLYSKKIIETTSKIIDYRLYLKNKNVLMPGLEIVEE
The following text describes a protein:
Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Sequence:
MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAAAAAAAASGFPLAPEPAALLAVPGARREVFESTSFQGKEQAAGPAPAGPHLLHHHHHHAPLAHFPGDLVPASLPCEELAEPGLVPAARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPCSGPTSASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQHGREVHSWQGSRAGSEAVARQLQSPQPSEALLHISDESLGVTSGALGCWVGGLGGNLGVCLSGLPREHHAGPAVPSTYAVSRHGSSPSTGASSRVPAASQSSGCYDSDSLELPRQEEGPSEDSGPGGLGSRAQATNGGSERSQPPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPSDVPRPGPAVAGPLNSCRLSARPEGGSGRGRRMERGSPSRSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCRDIVSLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQALRRRPGFSKILHIKVEGGC