lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Ensures, when in complex with COG2 and FPP2/VETH2, the correct secondary cell wall (SCW) deposition pattern by recruiting exocyst components to cortical microtubules in xylem cells during secondary cell wall deposition by recruiting EXO70A1.
Subcellular Localization:
Vesicle. Note=Present in vesicle-like small compartments which exhibit microtubule plus-end-directed and end-tracking dynamics.
Sequence:
MDRRSWLWRRKSSEKSPGETESTGSVSSHSERFSDDQRSQSPELNSKPVTREEEATADIKILTERLSAALLNVSLKEDLAKQHAKVAEEAVSGWEKAENEAAALKQQLDASTSKVSALEDRNSHLDSALKECVRQLWQGREEQNQKIEEAINNKCKEWETTKSQLEARIEELQARQDVTTSSVHEDLYPKLEALEKENSALKLQLLSKSEEVKIRTIERDLSTQAAESASKQQLEGIKKLTKLEAECRKLRVMVRRSDNSSDLKSSIDNQSDYSGRVSFSDNEMQSPSEKIIGKSSMATSVDIGLMDDFLEMEKLAALPHSEPGRKHSESNKELEKSNAHVNQLKHELKTSLRRISELEEKVEMVEVEKLQLEMALNGSKEQIEALQSRLKEIEGKLSEMKKLEAENQELELLLGESGKQMEDLQRQLNKAQVNLSELETRRAEKLELTMCLNGTKKQLETSQNRLKETERKLTELQTLLHLTKDAKEAAEDGLKAANGKTEAIESRLKDVEAEAESLILKIKSLEDVTEKERALSAKHNSKCNELQDEISKLKQELEHHQETEPAPNHIKGFELKQEKELAVAASKFAECQRTIASLGQRLQSLATFEDFLIES
The following text describes a protein:
Function:
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MIDRIPVPFLNPLFKFLFNREWDGPSTFSILMMIGFLTASYLLPKELKRRKLEPEHSDWLLLLGILGTLVGAKIFFVFEIWDQIFVETPGFDGKYIYPLTHWYGFPGRMSLWDNLFSGSGLVFYGGFLFGILFITLYMKYFQLDIASYLDAAVPSMAIGYAIGRLGCWVSGDGCYGFATNVEIPLLVFNYHGAHPSGVPVWNTPLIESIISFLFFFYFQFWARNQNFKKFSIGAQYLVLHGFARLLVEFLRVNKAVFPLMDPPAFVNIPNAEQNPEFLTQYYWHGFSQSQLVSIIIILVGAFFILKWKLWKKENTSNI
The following text describes a protein:
Function:
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
Subcellular Localization:
Cytoplasm.
Sequence:
MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLEAAGILEYEAIDIYNVDNGQRFSTYAIAAERGSRIISVNGAAARCACVGDKLIICSYVQMSYAAARLHHPKVAYFEGENQLQRKAKAVPVQVA
The following text describes a protein:
Function:
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Not required for IFT complex A ciliary localization or function. Essential for maintaining proper microtubule organization within the ciliary axoneme.
Subcellular Localization:
Cell projection, cilium.
Sequence:
MMLSRAKPAVGGDLPQADKRKKKGRKIPKLEELLSQRDFTGAITLLEFKRHVGEQEEDTNLWIGYCAFHLGDYKRALEEYENATKEENCNPEVWVNLACTYFFLGMYKQAEAAGFKAPKSRLQNRLLFHLAHKFNDEKKLMNFHQNLQDITEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGKAAEAELKSLMDNASSSFEFAKELIKHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHVKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEVFLLIQSEKMKNDYIYLSWLARCYIINKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMILAGREPKETLREVLHLLRSTGNTQVEYIIRIMKKWAKENRVPV
The following text describes a protein:
Function:
Function prior to stable branch point recognition by the U1 snRNP particle to facilitate or stabilize the U1 snRNP/5'-splice site interaction. Has a direct role in the assembly or function of a catalytically active spliceosome (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MDYGDIYIAEETEWDKYNRQINKNPDDFDAWEGLVRASEHLEGGVGRNSSKQAINTLRSVYDRFLGKYPLLFGYWKKYADFEFFVAGAEASEHIYERGIAGIPHSVDLWTNYCAFKMETNGDANEVRELFMQGANMVGLDFLSHPFWDKYLEFEERQERPDNVFQLLERLIHIPLHQYARYFERFVQVSQSQPIQQLLPPDVLASIRADVTREPAKVVSAGSKQITVERGELEIEREMRARIYNIHLQIFQKVQLETAKRWTFESEIKRPYFHVKELDEAQLVNWRKYLDFEEVEGDFQRICHLYERCLITCALYDEFWFRYARWMSAQPDHLNDVSIIYERASCIFASISRPGIRVQYALFEESQGNIASAKAIYQSILTQLPGNLEAVLGWVGLERRNAPNYDLTNAHAVLRSIINEGKCNTGITEVLITEDIKLVWKIEGDIELARNMFLQNAPALLDCRHFWISFLRFELEQPLNSKNYTEHHARVSNVMEMIRNKTRLPPRTIMDLTKLYMEYLCHQSNDPSVLQEYLLIDRDVFGPFSVRESHWKKLDEGQDLKQVSTRLLSTNGHPGISVNEAKIKSGESPYEKYYRLQGVVETVTSGVAANGSS
The following text describes a protein:
Function:
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNQTRVFLIFAWLMVAALLWMEWGKDKAAANAPTPIASQAVPAARDPDAAAPAANVPSAQAIPQAGSPAAVPATSTTTATPATTGAAPAITLTSDVLRLKLDGRSVLDAELLQFPQTKDGTEPVKLLTEDAAHPYNATSGWASERSPVPGVGGFRAEQPGTTFELAKGQNTLVVPFVWNGPNGVSIRRIFTLQRGSYAISIKDEVINKSDAAWNGYVFRKLSRVPTILSRGMTNPDSFSFNGATWYSPQEGYERRAFKDYMDDGGLNRQITGGWVALLQHHFFTAWIPQKDQASLYVLAQDGPRDVAELRGPAFTVAPGQSASTEARLWVGPKLVSLLAKEDVKGLDRVVDYSRFSIMAIIGQGLFWVLSHLHSFLHNWGWAIIGLVVLLRLALYPLSAAQYKSGAKMRRFQPRLAQLKERYGDDRQKYQQATMELFKKEKINPMGGCLPLLIQMPIFFALYWVLVESVELRQAPWLGWIQDLTARDPYFILPVLNIAIMWATQKLTPTPGMDPMQAKMMQFMPLVFGVMMAFMPAGLVLYWVVNGGLGLLIQWWMIRQHGEKPSKIIQANAK
The following text describes a protein:
Function:
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPQISPNAPLEGNVSPPPTQPHLDDNLHNGNGNGNGIHSSSSNINKHGSNINGNNDSNRSSPAKSPKRPVSSSFRIQNTSRYDNDEEDLAASEQVAGGDRQVPDYWQQRNGATTGATSGRQSRAISPGYLDNMSENSEQPPVVPLVRSKSRPEISSAAASRYNNLSYWKARRVVFYRNGDPFFPGVELRYRPGRDVTSLDNLLDKISPKMDLPRGARYVFSMDGDRKYHLDELEDGAFYVVSSFKAFKPASYGKKNGMWYASPGNQGWGSKPASRKPSIMEADLGTLSTTSGSIKRSAGRVIRIINNLDHSVQCRVLLNLRTSQPFEEVLEDLGQVLKINGAKKMYTGTGQEVRSFSQLRNEFADVDTFYLATGTALIAGSPIRRSRSRPSVVAAAPILPTDELPKVPLRGARPRSKSRPRILYAPESEILRPNGEYTMLDIMKEEPTKVTIRGLRRTFYPPVHHAPADNSPPDKKLQLQWVHGYRGIDARRNLWVLPSGELLYYVAAVAVLFDRDEDAQRHYTGHTEDIMCMDVHPSRELVASGQKAGRDRKSQAHVRIWSTESLQTLYVFGMGELDSGVTAVAFSQLNGGSYILAVDSGRESILSVWQWQWGHLLGKVATLQEGLSGAAFHPLDDNLIITHGRGHLAFWHRRKDGFFERTDIVKQPSRSHVTSVQFEPDGDVITADSDGFITIYSVDSDGAYFVRTEFEAHNKGIGCLIMLGEGTLLSGGEKDRKIAAWDSLQNYKKIADTKLPEAAGGVRTIYPQRPGRNDGNIYVGTTRNNILEGSLQRRFTQVVFGHGRQLWGLAAHPDDELYATAGHDKHVALWRKNKLIWTIQTGYECVALAFHPFGTLAAGSTEGHLLVINCENGAVMLTLRVCGSPLNCVAYNQVGDMIAMGSQNGSIYLFRVSRDGFSYKKVNKIRGSQPLTHLDWSMDGNFVQTVTIDFDLLFWDAKSLSPERSPIAMKDVKWLTNNCTVGFLVAGQWSNRYYSTTNTIVATCSRSAAHDMLASGDAEGYLRLFRYPCISPRAEFHESKVYSGMLACVRFLCGDHTLITVGGTDASLMVWDIVEE
The following text describes a protein:
Function:
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of Pdx1.
Subcellular Localization:
Cytoplasm.
Sequence:
MSEITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYKYS
The following text describes a protein:
Function:
Acts as an atypical protein-lysine deacetylase in vitro. Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues. Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo. Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate. May activate transcription.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAEVQIKESTVKVSGQTLFYREALPVAPGTNKPPVLLLHGIRFSSQEWQNLKTLHTLAAAGHRAVALDLPGLGHSADAVAPSPLGELAPPGFLQEVLESLNMVPAVLISPSLSGMYSLPFLLSSPQSVAAYVPVAPICTDKFSVQDYAHVQVPALIVYGDKDEQLGELSLRNLKNLPNHRVFCMKGAGHACYLDDPDTWHQGLMEFLSSLK
The following text describes a protein:
Function:
Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in the production of high-mannose type N-glycans during plant development and fruit maturation.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MPLLRLRAYLNRRTLKNLLRPIRKIFHMLAMSQPNSEPELQSSSASRPPPPFDPMEPSVPISYPIKTLEDLESQSYFNSFHYPFNKASVALQSGSSSSLPNRRRLLVCHDMKGGYGDDKWVQGGTNPEAYAIWHWYLIDVFVYFSHSLVALPPPCWINSAHRHGVKVLGTFMAEWDEGRVICDRLLSTKESAHLYAERLAELADSLGFDGWLINIEVKLDIEQIPILKEFVSHLNETMHSLVPGSLVIWYDSVTIHGDLRWQDQLNEKNKPFFDICDGIFVNYTWKENYPSLSAAIAGDRKFDVYMGIDVFGRSTYGGGQWNTNVALDVLKKNDVSAAIFAPGWVYETKQPPNFQSAQNHWWALVEKSWGILRNYPKLLPFYTNFDQGRGYHFSIDGTKVSDDPWCNISCQGFQVRSEGDSQLGLSLHFSSTMNESTSILLTSGDFNQFSSKFSKVIPTHRLEKPGNSFGWVLQEGSIALESGDMLTEIHAVCYRSKHESSACSSVKYFAELGHLTIRTSHEKKLDFLASSSWLVDGQFIKWASGSRGSKTLSIKIVWKLKHGTSTAFSNYNIYVKNVTKQVEEVAEYLGTAHVEAFYVSDLVVPSETSSLKFIVQICAADGTCQNLDDSPTFTVDAEGPL
The following text describes a protein:
Function:
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
Subcellular Localization:
Cytoplasm.
Sequence:
MQGSATGLAYRGRTASIGFAHGPLVRVGADTNGERVAGNLAEEALALRAAIDAASGQIADLAGIAGGEAAQILEFQVALLEDEDFIQAIFASIGDGDPADVAWRSALDAQIADYNSAADEYLKARSSDLADLRDRVINILRGDGGPALEIPSGAVVCADDLPPSRFLEIDWSGGGGLALLRGSPTSHVAMLARARGIPMVVQLGAIPDVRANALLDGEGATLELDPSAEQVRLFEKRRESHRKSRASARAILRRPTASWRGERIKLFINIQRVDDLEHPDAQYADGIGLMRTEFLLTERGSLPDEETQFQAYDAVLRWADQRPVTIRTFDAGGDKPVAGFTLDGEANPFLGVRGLRLCLARPEIFAIQLRALARAAVRGNLKVMFPMVTSAAELEAGRKLFADVVQRLQADGIAAMLPELGIMVEVPAAALAITSFKTSFFSIGSNDLAQYVLACDRSNGALAPLMDPLHPAVLELIARTAEHGRRAAISVSLCGDMASDPRCLPALLNCGLRELSVNASALAQIKQTIDRLSSGGGLD
The following text describes a protein:
Function:
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections. The first step of the pathway is the formation of the heptaketide backbone by gsfA which is initiated by priming with acetyl-CoA, followed by sequential condensations of 6 malonyl-CoA units. The resulting benzophenone can undergo a spontaneous dehydration to form norlichexanthone. However, the true precursor for the griseofulvin biosynthesis is not norlichexanthone, but the heptaketide benzophenone that is O-methylated at 3-OH by gsfB to produce griseophenone D which is further methylated at 9-OH by gsfC to yield griseophenone C. Griseophenone C is then substrate of halogenase gsfI which is responsible for the regio-specific chlorination at the C13 position to form griseophenone B. The cytochrome P450 gsfF catalyzes the coupling of orcinol and phloroglucinol rings in griseophenone B to form desmethyl-dehydrogriseofulvin A which is further methylated at 5-OH by gsfD to yield dehydrogriseofulvin. Finally, gsfE performs stereospecific reduction of enone 18 of dehydrogriseofulvin to afford the final product griseofulvin.
Sequence:
MTVLFILSAGLVAVFGYLVSWFIYCRTLHPLSKVPGPFWPSVTRLWLTYAVSRGELDVVQRDLHRRYGPLVRIAPDEIACADPEAIRKIYSTTSPLNKSDFYHIWDVGAFSKYPNAFAIVDENMHFERRRIVSSVYSMSTVLTLEPYIDNCSRLFVKRMTERTVPHEAIDLGDWFLWYAYDVIGELFFGHSLGFIENRGDEGGFLASLEVMLPVLTIAAASSPLVRGLIMGLFTLSSTARKGLKGMNHIIETARASVDKRASAVAEPGKGERKDLLHNLLNIVSSKGDKLDFGIEDVKNEAFAALTAGADATMIELQAIFYYLVKDRSVYEELRKEVDQAVETGKLSEFPSYSEVVQLPLLKATIKEALRLHPAVGFTMPRVVGQAGIELLGMYIPPGWKVGMNAAVVGRDEGVYGTDANTFRPERWIERTDSDMDRCNNLVFGAGTRTCIGKQIALSEIYKMVPLLIRKFDFALVDPSKSWTTHDYFFNKQSGVQVKVTVRGL
The following text describes a protein:
Function:
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAHKRSIHDQSMAKLQLASGWTPSRSGMNQALRPLVAAALRKLRHSLPHLLASAHHYERRNPAAYSGSVATSRLCRNLGYFRVNYATVVAFSLTALFLAHLFSLLVLLGILGTWCFLYVFRDCDQPVVLFGQTFTDREMEHEPNLLAGLAQHVLPAVTFSEDCMP
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Golgi apparatus.
Sequence:
MDNQQRKVQGSSSNTFIKRAFQHLKSLFTVCFTGADYLESDIELICQNEIQPQGLEKLNADSSNFYCNSLTSNQSLTTSMEALDLSSSLTTPHADKLLKLSNLIAAKSFTTERKLSAAEFLDSREIHNPFTYGFLGILYGTSRTPYLHAQYANSFMSESAVPISIELNNREAKASMNLAEKNFPEGFEDFVSFLENPNIPLTVLLHHVMLYDLYSNNLKDAVWVAVTNYMKNLVGNYGYTELHIRAAQQMFGHPRFLLVHPEDIYCISGSSDWVCVSTQHFHCNIHVHSVSGNAIRKSRNPIIQDLSSICQNSTEFGWLALTHALRKKGAIFPIHAYLNFNAKLYEECIPPSILYFNKNDENINVGNIEDITNYMYETFINEASLCDKFMKRKHERIETPLSSQGREISNTLSRKRGAKGSNPFEIENMMPHA
The following text describes a protein:
Function:
This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
Sequence:
MSESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKQLVVLDEEHEGISPDELKDELPERQPRFIVYSYKYQHEDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVSTKITAKGDSLERRKELLQSDEGSRFCISASLRLLLNDLWYLRLCPCSGTLHLEFFTVHLECFCFFHLRISALDAALQVLQKAN
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MLQDAQKAAQVFQGLKRDNPTVLGKLVPVIGDILLPGLGLSQPDLQTLIENVTVVYHSAASVRFDEPLRKAIDVNVLGTRRVLELCHKLKSIAAFVHVSTAYCFCNRDHVDEIVYPEKIPYQRVIDVSEWLEDKLQEKILGQVMGGRPTTYHYTKALAESLLVHEGGNVPIVILRPSIVTCSVKEPMSGWVDNFNGPAGFVIATGKGVLRSMVIRPNSSADIYPVDMVANMMITSSWHIWKQPPMNAPFVINCTSGSFRRLTWLQIFQYSKPLVLKYPSSEIFRYPGGSYKTSHFWHSIACQLDHNLPAFIVDTLARICGQKPFLGDVYKRIHRAMGMLEFFVTHEWTFAVDNLRLLMTKLEGSDRQTFDFDIRTIDWVPYLENYILGVRKYVLKEDPSTIPAARKKLHSCNGAKAQTKAKKKAETKATSWTAMCNSASEPAQRIYYVGLLSQLLLLAGAMRLLVKHSQTFNDLWWTLLSNLLQLSVRISLALRSTRTS
The following text describes a protein:
Function:
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May play a role in the protein folding, transport and assembly.
Sequence:
MPPEVRGNKRAFFDISINGEPAGRIVFSLWNHCCPRTVENFRAFCTGELGKMNGHYASYQGSVFHRVIKGFMIQGGDITHGNGTGGYSIYGRTFDDENLALKHKKPYLLSMANRGPDTNGSQFFITSEEVPHLDGKHCVFGEVIKGVEVVKAIENLETGNEDKPVCKVEITHCGEMVRKGDVVGNAGAAASEPEPTGVKMEDEPKTRNWLMRYSKSPESREEKKKDKHGREEKRDRRRRSNDRHGRDRRSRSRSQSRDRNRRRDDRSGRDGRVGRNERDDRSGRDERRDDRRSAPTKDGIKVRGRGKLTFLGGRTRSTTPPHWKREESKKLTLEAHQKRQEELEERQKRAAQREKEEAERNARLEKERVERQNQRELERQKQEAERELKRQQENEESGNRRRRRSSRSGSENDESELEEPKNRSASPRKRSSSSSSSSSSGHSSDSD
The following text describes a protein:
Function:
Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal.
Subcellular Localization:
Early endosome. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
Sequence:
MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGDESPVVMHHHGRHFIHIRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDYGYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLPSKSQALNVRLHLPLPRGVVSLSQELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFELPRHTCSGLQVRFLRLAFRPCGNANPHKWVRHLSHSDAYVIRI
The following text describes a protein:
Function:
Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
Subcellular Localization:
Nucleus.
Sequence:
MKIYAVREPVFSGPTPSFQNVSNDIPLVIDNGSWQLRAGWGGEKDPKLVFDNLVSRYRDRKLSRTSTLVGNDTLIEVGSRSIARSPFERNVISNWDLMEQVLDYTFLKLGIDRMEHPICMTEPLANPTYVRSTMTELLFELYNAPSVAYGIDGLFSFYHNTKPSSSGIVLNLGNAASHVIPVLNGERILSEAKRISWGGSQSSSYLLKLFQIKYPSFPIKMLPSQAELLMHDHCHVSSDYTHDIAHALDRDILERDEIVLQFPYTEAAAQEKSQEELELIAERKRESGRRLQAQAAIKRKEKAAERDRELATLTELQQQSLVLSRRAFQRALEEAGFEDESQLNAQVKNVQAKIRRAQRDQQRQEESEGSLDVTEIDVEQAFPLLNVPDAELDEAGLRQKRHQRLMKANYDARVRAKAEKAIEEAAEAERAEADERLRLENFSTWVNEKRETHKILLEKISKNKRLKFELNDRKSHASQMRMKSLATLASEQPIQKRKRKDQSEDNFGARDEDWKVYHDVLTAEQLEEERKKLLDQIYSLEKQLLEYDSQFTQANTYDTLNDPRATLLYAFTRGVSDFDVNDVAQAFQLHLNVEQIRVPEVIFSPSIVGIDQAGILEIMRSILQRHSLEEQQKLVSNVLITGGLGSLPGMETRIKRELTSIMPVGSSINVFRASNPLLDAWKGASEWSVTEKFKAAKVTREEYLEKGPEYIKEHSLGNINS
The following text describes a protein:
Function:
Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8.
Subcellular Localization:
Cytoplasm.
Sequence:
MALVPYEETAGMGLQRFHKPLATFSFANHRIQIQQDWKQLGVAAVVWDAAVVLSTYLEMGAVELRGCSAVELGAGTGLVGIVAALLGAHVTITDRKVALEFLKSNVQANLPPHIQPKAVVKELTWGQNLGSFSPGEFDLILGADIIYLEETFTDLLRTLEHLCSNHSVILLACRIRYERDHNFLAMLERQFTVSKVHYDPEKDVHIYKAQKRNLREDL
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MFGRNNHDRETEVNCEMEDGDGGKKLRTSHMFCKTLTASDTSTHGGFSVPRRAAEDCFPPLDYEQLRPSQELIAKDLHGMKWRFRHIYRGQPRRHLLTTGWSSFINKKKLVSGDAVLFLRGNDGELRLGVRRAVPLKNELLLEAVNSTDSKLRTLSAVASSLENRSIFHICFNPRTGASEFIVSYGKFLKGLNYPFSTGMRFKVGFENEDANQRSHGLISGISEVDPIRWPGSKWRCLLVKWDDDTKCNHRNRVSPWDIEGISSSISMTNCLSSVSKRTKLCFPQGDLDAPILDGNGRPDSMETECFHRVLQGQELVRTRTHGVAWSHSSDTPKCQGSCERRFSADVWNCKMNDAMSGFRHRNANGFAYQPLGFSESVRFSEVLQGQEMSQAVPSFLGAALDARVQNGRIGSFDYVHRSTVSQGYPLQQFNLPATEVHSPSSVLMVNQTTALQPELEGMTNREEANGSRYAPIAVRREAERWPSTQQPRASGNGSEVFNTTEASAPATAAKPVDRGVGRSSCRLFGFSLTDKILGAEEDGVKEGNYEADHQTPRALDLFGHSQSAPSALHALCAAPLGI
The following text describes a protein:
Function:
Mitochondrial-specific pseudouridine synthase catalyzing the formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of mitochondrial transfer RNAs.
Subcellular Localization:
Mitochondrion.
Sequence:
MLLGYCGSGYYGMQYNPPHKTIEGEILTKLFDVGAISEENSLAPKKNSFMAAARTDKGVHAMLNLLSLKITLREDTVAKLNAALPPEIRVWGIQPVNKKFNARSACDSRWYQYLIPEFILIGPPRSSLLHRNVGGCYREDGSQEVWDTFLEQTRGRFSGDELCRLQDTAQKLSESDPLVQDYVGLLSGTLSGYCLSPSKLDAFEAAMQEYVGTHNFHNFTTGKLWGDPSAQRHIKKVVVSQASPGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQGLLLEGPVFDGYNTKLRNLLYCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNRLATPLI
The following text describes a protein:
Function:
Sodium-exporting ATPase. Required for the extrusion of Na(+) from the intraerythrocytic parasites to maintain a low cytosolic concentration of Na(+).
Miscellaneous:
MISCELLANEOUS: ATP4 inhibitors cause swelling and partial lysis of infected erythrocytes, probably due to the osmotic swelling of the intracellular parasites because of Na(+) accumulation in the parasite cells.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSSQNNNKQGGQDINNKKDSDDIKPSVSKEDLINSLKNDELNKNTTMDQNDMKKNENMNIKKNEVLNNSNNVEDGDNENSKFMNKSKEGLNNINGEKNDDNNSIVKVEESPKSIGYNYYASESIENLCKEFGLESINTGLNSEQVKINRDKYGENFIEKDEVVPVWLIFLSQYCSPVVLLLLVAAVASLALNEVVEGVAIISIVTLNACLATYMEKSSGDAIGKLAEMASPQCTVLRNGQKVVIPSREVVVGDVVLINTGDSISADLRLFDVIELKTNESLLTGESEDIKKTIVADNLSTPFATNLCFATTSVTSGSGKGIVISTGLDTQVGKIASQLKKSSKGSKLTPLQVALNKLGGLIGLIAIIVLVVIISLAVIIKYRDPAHADKDPTFVIIIIGVGFAVSSIPEGLPMVVTITLSAGAKDMVKKNANVRKLPAVETLGCCSVICSDKTGTLTEGKMTAINAVTICKNSSLSDENNKLTKTFDFYPTKGFEPCGGLFDSNELTSEKKKEIVIAKNQNTSYDKVLYNYGNPSNKSVIVDKTRSLMFAAYLNSYDTTLSRDPKTLKWGIHGNMSEGPIVVAAAKVGYSFINNPNHKSYLDNFQRLDDLEVTFNSSRKMKITFYKLKTVNVFENVYLDKPGKVYTHVALIKGAPDRLLDRSTHLLEETSMKKVQVSWNSTITQEERNVLIKKNLELSQKALRVLSICIKPLTDQNIEELKKLEDADERLKYVNYDENGGFIPMGYVASFDPPRPGVKEAIQTCREAQVKVIMITGDQKPTAVAIGKLIGLIEEKSEQVEDINSLAIECSELHINKNPNEPILPNDQLDEFTDKILIYSRAQPEDKITIVQSLKRKGYLVAMTGDGVNDAPALKAADIGVAMGINGTEVAKGASEMILIDDNFCTVVSAIDVGRTIFSNIQKFVCFLLGTNIGEIIYLSVAIVAQMPFPLEALQILFLNLMTDGCPAVALSREPPNDDNMKTPPRPKKQPIMTKRWWFYGILPHTIFEALCVLLSLAFSLYICTGFYNLNGIHNLCKTVNLVDVNDANVYHEYKYFCSSYEYRISTDYVGWVTNVSFWDPQNNEAVNFWGAAKGKVENINPLSDIVHPELRLRMQDGCSGDLTLDENGWCRPKDNKTSDGYNDELEGILKKGFEDVTAKGSKRGRTMAFISAVWCEMLRAYTVRSWEPFYKVFNRNMWMHLACSISATLTFLSTCIPGITSILNTTCLLWWQYLLAIFWALLNLFLDEIVPKVIYRRKYMTIKN
The following text describes a protein:
Function:
SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MAASRLELNLVRLLSRCEAMAAEKRDPDEWRLEKYVGALEDMLQALKVHASKPASEVINEYSWKVDFLKGMLQAEKLTSSSEKALANQFLAPGRVPTTARERVPATKTVHLQSRARYTSEMRSELLGTDSAEPEMDVRKRTGVAGSQPVSEKQLAAELDLVLQRHQNLQEKLAEEMLGLARSLKTNTLAAQSVIKKDNQTLSHSLKMADQNLEKLKTESERLEQHTQKSVNWLLWAMLIIVCFIFISMILFIRIMPKLK
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MLAASARSTSAKVAAGVSLAMIGATSSTLVAKPIYNDEASSSDASKLSIYPEPDAKVEVVPVQTELERQVGSARRAISHVTADTRSSVRSLIDRWISVERSIEGEVKSIIPPTEPLTPGLLYVGVATLAGSIFTRYRAFPVRLLTPPLALVVSLNYFNPNLASNLGAYYTQVEHKYAPALTEQRRTWQKHAQKYLDSTTNSMHELKDKTEQGLRSGLHSVEQQTGLKVSQVVAAKDEAKSAIKDQIKAV
The following text describes a protein:
Function:
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MFNRSEKVAEAIHELVSGLIVKGMKDPRIGFITITGVKVTDDIRQATIYYTVMGDDEARVSTARGLASATGFLRREIGKQLRLKFAPELHFKYDQSIEYGNRIDQLLKEIETEKGSDD