The following text describes a protein:
Function:
Regulator of histone methyltransferase complexes (By similarity). Involved in the establishment or maintenance of higher order chromosome compaction and closed euchromatin structure. Accessory component of the polycomb repressive complex 2 (PRC2) involved in maintenance of transcriptional repression and regulation of transcriptional activation or elongation; functions in a PRC2-dependent and PRC2-independent manner. Reduces levels of H3K27me3 histone modification.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to transcriptionally inactive euchromatin regions on salivary gland polytene chromosomes. Partially colocalizes with PRC2 core complex component enriched polytene chromosome bands. Concentrated around transcription start sites. Can bind to chromatin independent of the PRC2 complex.
Sequence:
MVVSKDNNKRRRKETETPPPPPPVPPAGSSLAPPSAVAAIESSPEMPKRTKVQAQRKFAQGQSAPSSSSSIAYSAAAAAAGSGSGPSTSGADSNQPPIEILPNKCPKPQDFLTFLCFRGTRALPAHLDFLNQGKSKDSEASSTGANNNNNARKPNNSRASLAGNKKKRGRPAKGATKKVDVVAPIPDPTEKPSTAEKPASDKNNLIAAEAPKIPSRNPTPVLPGAVRKRAEVVTDGNRRGARGRGAGISHDKTTPAALSKDNKRRSNRASTKESKPVIDDDNSEDLDEQEADDDEDEFFSAHDATSRNGEEVKADSPVKAEPTKRGRPSAAKKAVEPAPEGQTVLKDKAPVKRVRQRESPIFIPSPESSGRMTRQRAFFEPVKVPPHKEEPGAHDPPKDEPKKQPETPPSKTEKEQEPTKQIKEAKEKTNSSIYAKEAKQQLENGDSLHGAVAKGKKSLNVFDFSSDDEQPLAKSIKLKKGAKGASPKKGGAAPIAPAARNRKAAAKKLDKEKEIEKEKQREKEEEIERDKAKEKKDKEKEKEKEKHPVPESKVEEPPSGGKRGKAGKKKAEDAPADEEDLAPPSSKKVATNARGSRKSAKSKASEDSAELEPQRSQRPSRKTKEAAAIYMGIIGHKLQLADDEEDDLSMSSFPDIPNVKEMEKMENEIKRNAAGKLNVPEASTVLSAGKSTRKPSPRPKDSPVTAPVEATRNESPSPPEAEEEKPPPPARRGRPPKQNKVNAGPAHKPRIEGMLVKKGSLAKMSEQQAKPKAKSEHSKVDSDEEEDFLINEELNETKRKLEKSFSDSDDEPLAIKVPAVAVKEKELLPPKMASPPPKLVPVPSPISVPTPAVSVAPSLAVPSILPTSTGTTQLTMLPLTAKATSSLGSMPMFPSIQASYSPLKTMEKKPPVPTSKILNVPATYALPGSASGAVSFQKTSSYLPQASPHYHSGYVRPPPTPTHQFGGGAPSGSKTPSQGSSPLKYQTPPTTYPPPIEAYQCPKINPNFLTPKYERSPLPRSSTSSFPSPSPVKFQPTSGTTATTVGTPSSATKSPLAPPPPSPPVSQVVIQTSSLNLSMSIAATVNAAPMPVASTSAAAAHQTTVATTVTATSTPPPAHSNSAATGGGAGANSDPLKDEIGSILAQATLMPSKEESGKIFGIASVSLAQSSGPDNTKCTLGKCGSIHKPVLGPVVPTEGYFGDQLSSKERRKAKVNMTHEQIQKWLIECSSNPDEIQDDLDDDFDDSLRPQQSTTPPPTRDDKELSASFSSSSKNTRGDLGKSESAWSAKGPSLKATPVLVTPPNRKELHEQADSKDCDALDYDKSSTPVNLTQKITSNESLAVEKKVNDRKGKESAKAAASKAATQPRSTAATPPTPISSTPTPASLTPSKSSPTPPPAVKQKAEKGKRNATAGGGATALASPPAAPTPANPKRTPVYNQKNAKAQQQQAETKPASNPPSGAGTKRESVYAFGKDDESGSKSGNRRRTDPSPVPAPALVPNALSERSPTKKRAAAAAAATAVQLTLSPTENCKIEGKPSKAPTGRGAKKQQQQAPAPPAPPVEASGDSDAEGATFYIPLQGAGVGGSGDGGIQGVAVKLGREGPDGPNQKVVMQATLVTKAQMDTNSKPLPESLNTNELVKTLLHAASNDAASTTTSLKSLPKASTSAAAGAAAAPGASSLVRVNSNSSLFSGSAKSRTAAQTSSTAAAVAKKYKDDTPIKMANNTAFPRHDDPTQMVEAPIFRPTEKEFADPIEFIERITPIAARFGICKIIPPASFKPECRISDEMRFTAYNQYVHKMLHRWGPSAKELSAIKKYLATQSIVMNHPPWIGGMEVDLPRLYHTVQELGGLKEVIEKKKWARVAEEMCIPKLAQDRVTKLDDIYCKYLLPYDTLSPAERQKLFDEVEADWAKREARARRNADRFVNTESVSNEEDDLSSDEDEESEEEIDGVSMECIVKGRSMPLSQFYRIARNTMALWFKSTDPTVNEVEAEFWRHVAVRDSHVCVHSGSIDSSGWGYGFPSPGPKGKGSNYARHPWNLKVLTNNSGSVLRSLGPVMGVTVPTLHVGMLFSACCWYRDPHGLSWIEYLHTGASKLWYGIPDDQSANFRAALTSLIPTHCQNKTIWLPCDTVMVPPHMLTDRGVSLCRIEQKPGEFIVVFPRAYTSSLATGYVVSESVYFATMSWLDLAKDDFRDIHESCEPAMFSLEQLLFALGYDQRVNSEALHQMLPMLNDVCEKESAAREQLRAAGVTSTEKVQAEKGQKAKKQQQPPYKSIESECDLCRANLYISMVRTEDGNIYCLQHALKNLNNGNIQAKQCKLIYAYNVDDIQQLIRQLQEKINHKAAVKKK