lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the tripartite ATP-independent periplasmic (TRAP) transport system DctPQM involved in C4-dicarboxylates uptake.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSVRHTIRAMYHMEQSWFSRVGQFTDSIEEFLIAFFMGAMTLLTFANVIMRYLFNDNILWALEGTVFMFAWMVLVGASFGVKRHFHIGVDVLINIAPARLRKLYALVAVACCLAFSILLLIGSWNYWHPFITERAWYETDDIPMPDMLQFLADWVNEGERYEKLPRFIPYAALPIGMALLTFRFLQIAWQIITGKLDRMIAGHEAEEDLEALKAELSEAGEAMMPKTQGKEK
The following text describes a protein:
Function:
Putative phospholipase.
Sequence:
MSSLNNGIPEPLLKFLAAQFNWTRSQVAANQDDVFWQQVGLIMAQYDGLRAGYGANVYDKHVLPEFAFQLLNGNGDFFDIIPKAVDVTKMSSREFHDWRMRNGRCSALIKLTGDFSDLFMSHSAWYIYQAMNRIYKHCASYNFQATITHAKKISFSSYPGYLESLDDFYLMSSGLVMLQTTNNVFNTDLQQYIQPESLQSWIRIRTATALAQTSEDWAELAGRHNSGTYNNQYMVMDLNKFTPGQPLLDGTLYVAEQIPGTWEYADVTKMLSLGYWPSYNVPFFEKIYNLSGYPAVVKQHGTDDSYELAPRAKIFRRDQTTVVDLDSFKAIMRYNDYKNDPYAKGDPYNAICSRGDLESDSPSPGGCYDTKVTTYSMALKLQSQVINGPTTSHGLPPFSWSQFPNASHLGMPEVFNFTFETMDAGW
The following text describes a protein:
Function:
Probable transcription activator that may act as growth regulators in response to water deficit; Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MVRHDSTRYLDYIILNNSFIHLLKNKDFMILKHVRMLGGASGSETNIDHEVFKPTAGAQIRKKSKSKNIINNSSRRFSDEQIKSLESLFKMENKLEPRKKLEMARELGLHPRQVAIWFQNRRARWKSKQVEQDYTSLKADYDALSHRFESLKKEKHALLEQLRDLCTRLKEPHEGSSSKDLDSGSENGDTNLELNNGNYSSGFSGALDMAIYSDEDDPRRKPNIIISSRKEESENVNVNQLISRHDDDDDDDADADDNEKASNYDLGSLFDQSCSNWWDVWSSNS
The following text describes a protein:
Function:
Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
Subcellular Localization:
Peroxisome.
Sequence:
MDIRVVALEREETHSVYGSAGIMLDKKYVITTANIVASLLNNSLKKYLGTISQRKVCSFSDTKNTTTFKIFWKETNCSKYHVTSGNIFATFICENLRLFLRRILMDWSIDTPKNNTGLDDILSVFFVIQINETGLIDGFTNCLRRWWDLIKNVEINQMDDILVKSAAFGNKTFLDSYSRGIVSNTVGPNNCLIVSDCALTPGSEGSPVFSKNTEIPVGIVISASSWWKGDWTGLTLILDIRAVLAELFQNDQIISKCMVHHRLLASTESSLIQIYCGPKWGTAIILSQEGVLLTNSHVIDLNHNVTLHVKGQSVGAKILYKTPNDEVFDLAVLQCDPAFLNSHNRKPIKSNHECLALGEEVYAAGFALFSKTISSHPMISKGCIVQSNEAVIRTTCCVNPGMSGGAILNRLGEIVAVIVCNSRLNGHVFPKFNMAIPYGTIKGTLERFLNSKDTAILSNLYSDDPKITSAWKKMTAKL
The following text describes a protein:
Function:
Single-stranded DNA-binding protein that may be involved in the maintenance of mitochondrial genome stability by preventing break-induced DNA rearrangements.
Subcellular Localization:
Mitochondrion.
Sequence:
MLKVSRLLHPRNQLLHKKLPGECVKGSIWQHAINTFAGFSTVRQNVVADAGKREGRVFAPYSVFKGKAALSAEPRLPTFNRLDSGGVKLNRRGVIMLTFWPSVGERKYDWEKRQLFALSATEVGSLISMGTRDSSEFFHDPSMLSSNAGQVRKSLSIKPNADGSGYFISLSVVNNNLKTNDRFTVPVTTAEFAVMRTAFSFALPHIMGWDRFTNRPSESISQSPSKVVPQLMEAEWDR
The following text describes a protein:
Function:
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Subcellular Localization:
Nucleus.
Sequence:
MASNETPNPSEGETPNVYRLNNRSSPPPSSIAGNSSQIGDGMDVPGYALSSQPGTLDSSARGMFDSQMNTAPHQRRAYNGEDSRRGSYVYGEDDGAADEDGPAFDGLRMRNLNAIKKVTDVTGEKVREAFEQFLEEYSTVSAETGEPTAVYRTQLEFMSHYELSTIYIDYSHLAERENGALAVAISEQYYRFLPFLLKGLRRFVRKHAPNLLMTSDSVMSQYQEENASQQVNSISQASGGSLGSRRPGHSTAATGGSTVSTPEQTERIFQISFFNIPVTNRIRDIRAEKVGTLMTISGTVTRTSEVRPELFKASFTCDMCRAVVDNVEQVFKFTEPTFCPNPSCENQAFWTLNIGRSRFLDWQRVRIQENSNEIPTGSMPRTLDVILRGDCVERAKPGDRCRFTGTEIVMPDVTQLGLAGMKPSSAPDTRGISRTMEGLNSGVSGLKTLGVRDLTYKIAFLACHVMGVGNNSNPQGDVLSHELDVNMLQHLNKGIDDTERDQELFLNSLSSDEINELKEMVKDERIYDKLVQSIAPAVFGHETVKKGLLLQMLGGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCAFVPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRGNLNMTAPIMSRFDLFFVILDDCNQKVDTELASHIVNLHMKCDDAIDPPFTMDQLRRYIKYARTFKPILTEDARQFLVEKYKELRKNDIQGYSKSSYRITVRQLESMIRLSEAIARANCVDEITPAFVAEAYDLLRQSIIRVDVDDVEIEDEEEAPATDAEPQAAAPAEPSTPDNRAASTKPLGRKKKSKLAISYDKYVEMMNIMVRKIADTDSQGGSELTAVEIIDSYLLQKEHELNTEAEYWSERKLALKVLKRLVKDRILMEIRGNTENIPFDVPEEILRERERVVYVIHPNSSVLDQLSQQSPR
The following text describes a protein:
Function:
Binds to beta-1,3-glucan. May play a role in recognition of microorganisms and in activation of the prophenoloxidase cascade.
Subcellular Localization:
Secreted.
Sequence:
MKGFVASVVLLACGALAADIVEPEDCTSFPCMIFEDNFDYLDNDIWEHEITMSGGGNWEFQAYVNNRSISYTRDSTLFIKPDLTSNWKGEDFLSSGTLDLWGMNGRGDVCTGNSYYGCSRVGSSSNIINPVTSARLRTMSNFAFRYGRLEVRAKMPRGDWLWPAIWMLPRNWPYGLWPASGEIDILESRGNDDFGTLGNQYGGTTLHWGPFWPYNFFEKTHAEYSANTGSFADDFHVWRLDWTKDNMEFYVDDVLQLTVDPGTSFWDFAGMGPFFDNPWAAGAKMAPFDQKFYLILNVAVGGTNGFFPDGIASKPWSNLSPTAFLDFWNARDEWLPSWKAGEDRISEGAAMQVDYVRVWKMESTEQ
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MSDSDEEEVPQKVSKGKSRKSKAKKPVKNFMQTIGNRIPKAKKKKNKKKQQPNKPRVSDDDDDEEDEEESEDSEVEMLCISSGDDEQDSTVDKKPKADDNKLPEGVEPTKWKQVNESELALRVRAMRESKAVPAPVVQKIERKQTQGLNNMQSLPRGMECIDPLGLGIISSRTMRLITERTATEPSNNEYVDADLRDKLTFFSERFDPVLFISRIHQFTSAADLEAGTLALKTDLKGWTQQRKQLVKENFDCFVSCKTTIDDIESKLKRIEEDPEGGSSYLETSIQGINSMANRAFEPLLERQAQADKIRAVQGTLQRFRTLFNLPSAIRGNIRKGEYDLAVREYRKANSIVLPTHAGILKRVLEEVEKVMHDFKRMLYESMEDPHIDLTNLENTVRLLLELEPESDPVRRYFGIQNRRIQILLENCTVDHESRMDHLQNKLNEKALLDETWKTIQQDLHESVDGGLVNSQPTDSGSEELDALRGRYIRRLTAVIIHLIPPFWKVALSVSSGKFGKNKSEEKAQGRYFGHSLEVVTGMIHEIISAYESKVQNTFLELEEANVICPYMSDAIMDISKACQAFDAKEAAPASAVESLRSLLFESTKLYIMKLCSWMRTSIDEESRNESWVPVTVLERNKSPYAISSLPLAFRSIMVAAMDRIDVMIKSLKNEATTEDTLMLLQEIQESVRVSFFNCLLGFAGQMEQIGGELGQIKENENGYYSHVEEENLFHHRPGSITDPQQQLLMVLSNIGFCKDDLFGEMYNKYKHVCLKFSAGEDDDKDKEELIESFSAIEEKVLAEYTFAKAQYVRTGATNYLLDAGLQWGGAPAVKGVRDPAVELMHTLVTVHAEVFAGCEPLLDKTLGILVEGLIDTLLSLFHEHKDTNLKLLDANGYCQLMLELEYFETILNQYFTSGASESLKSLQGILLDKATESCSRESDDDDKQQGGTISPDDLIALAQQCSSELLQSELERTRINTACFMESFPLEFAPESVKVAYASFRGSMDASSGVFMGAQAVGSTQRWR
The following text describes a protein:
Function:
Serine/threonine/tyrosine kinase involved in the control of stomatal movement in response to CO(2). Functions as a major negative regulator of CO(2)-induced stomatal closing. Does not seem to be involved in stomatal closure in response to abscisic acid (ABA) or light. Involved in the control of red light-induced stomatal opening. Is epistatic to SRK2E/OST1 function during stomatal responses to red light and altered CO(2). Phosphorylates SRK2E/OST1 and GHR1 to prevents SRK2E/OST1- and GHR1-induced activation of SLAC1, thus preventing stomatal closure. Mediates the phosphorylation of CBC1 and CBC2.
Miscellaneous:
MISCELLANEOUS: 'Suu' means 'mouth' in both Estonian and Finnish.
Subcellular Localization:
Cell membrane.
Sequence:
MSGLCFNPFRLRWSLRSKLPLEPSLPNLPCNPSSSKTNRYAEAETMEKKRFDSMESWSMILESENVETWEASKGEREEWTADLSQLFIGNKFASGAHSRIYRGIYKQRAVAVKMVRIPTHKEETRAKLEQQFKSEVALLSRLFHPNIVQFIAACKKPPVYCIITEYMSQGNLRMYLNKKEPYSLSIETVLRLALDISRGMEYLHSQGVIHRDLKSNNLLLNDEMRVKVADFGTSCLETQCREAKGNMGTYRWMAPEMIKEKPYTRKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKRPDFSNIVAVLEKYDECVKEGLPLTSHASLTKTKKAILDHLKGCVTSISSPFSSSSVPVNA
The following text describes a protein:
Function:
Sphingosine-1-phosphate lyase that cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Prefers C-16 dihydrosphingosine-l-phosphate (DHS-P) as a substrate. Regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs). Plays a role in the regulation of global responses to nutrient deprivation in yeast.
Miscellaneous:
MISCELLANEOUS: Present with 13100 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Localizes to the cortical and the perinuclear ER.
Sequence:
MSGVSNKTVSINGWYGMPIHLLREEGDFAQFMILTINELKIAIHGYLRNTPWYNMLKDYLFVIFCYKLISNFFYLLKVYGPVRLAVRTYEHSSRRLFRWLLDSPFLRGTVEKEVTKVKQSIEDELIRSDSQLMNFPQLPSNGIPQDDVIEELNKLNDLIPHTQWKEGKVSGAVYHGGDDLIHLQTIAYEKYCVANQLHPDVFPAVRKMESEVVSMVLRMFNAPSDTGCGTTTSGGTESLLLACLSAKMYALHHRGITEPEIIAPVTAHAGFDKAAYYFGMKLRHVELDPTTYQVDLGKVKKFINKNTILLVGSAPNFPHGIADDIEGLGKIAQKYKLPLHVDSCLGSFIVSFMEKAGYKNLPLLDFRVPGVTSISCDTHKYGFAPKGSSVIMYRNSDLRMHQYYVNPAWTGGLYGSPTLAGSRPGAIVVGCWATMVNMGENGYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAHVVDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFLDALYKLGPGEDTATK
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNVYIPILVLAALAAAFAVVSVVIASLVGPSRFNRSKQAAYECGIEPASTGARTSIGPGAASGQRFPIKYYLTAMLFIVFDIEIVFLYPWAVSYDSLGTFALVEMAIFMLTVFVAYAYVWRRGGLTWD
The following text describes a protein:
Function:
Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia.
Subcellular Localization:
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Sequence:
TMSGSISYLGLVLTLISTIGIIFTTIYREWKRNSVQASQQVLDRLYSCEGLWVRCTSPTPGQFQCDDYDTALLGLPPSLQAQRAMMCIAAIAAVAGIVAGALGLQCIKVMEGSNAKVHTGRAGGGLMFLAGALTIAAVSWYAADVVYQFHVEVITNQSFTYEFGSALYVGWIAGGCALISGALMACCNCGNEETDSYPAYTYKPPKASGGGNNTEYV
The following text describes a protein:
Function:
Probable toxic component of a type II toxin-antitoxin (TA) system. The cognate antitoxin is VapB5. Has limited RNase activity on substrates; activity is seen with a VapC5-VapB5 complex.
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Subcellular Localization:
Secreted. Note=Following 6 weeks of nutrient starvation.
Sequence:
MSTTPAAGVLDTSVFIATESGRQLDEALIPDRVATTVVTLAELRVGVLAAATTDIRAQRLATLESVADMETLPVDDDAARMWARLRIHLAESGRRVRINDLWIAAVAASRALPVITQDDDFAALDGAASVEIIRV
The following text describes a protein:
Function:
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.
Sequence:
MEAPSEDTKGPVPTDNDNYNPPPPPLPITQQPLGYNPVNPPYPANPSMANPPYNPANPPYPANPSMANPPLMMNNPAPLQMNQVTLHQPGTAAYRATEVPNLALMGLQQQQQQMQWMMPPPPSPSCPPGLECLTQLDQIIIMQRLNIVELMRGIDMANRYDAKNKFGQEVFFLAEVPTPFSCNCCSRLFHMKILDANDKEVMHYSRPYRCGLCCCCCCFTDCMEDMTIESPTGNAIGSIRQTARIGPKFQVLDTEKNKIFNVNGPFGVVDTDGQNVGSIVKGWSGMRSVVSQDRLDINSVPMDLDVKNKALMMGAGILIDYMLFQRVMANNNRR
The following text describes a protein:
Function:
Catalyzes cross-linking of the peptidoglycan cell wall.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein. Cell membrane. Membrane; Single-pass membrane protein.
Sequence:
MKRQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQILRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTLDALRSVVDLNDDDIAAFKKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKGYKRRYYPYGSALTHVIGYVSKINDKDVERLDRENKLANYAATHDIGKLGIERYYEDILHGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVIVTDPRTGGVLSLVSMPSYDPNLFVDGISSKDYSGLLNDPNTPLVNRATQGVYPPASTVKPYVAVSALSAGVITRNTSLFDPGWWQLPGSEKRYRDWKKWGHGHLNITKSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIPVGIGQGYWTATPIQMSKALMILINDGVVKVPHLLMSTAENGKQVPWVQPHEPPVGDIHSGYWEIAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAERLRDHKLMTAFAPYNNPQVAVAIILENGGAGPAVGTIMRQILDHIMLGDNNTHLPAENPVVAAAEDQ
The following text describes a protein:
Function:
Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.
Sequence:
MESIVISGISGRFPESENVEEFWTNLLNKVDLVTEDDRRWKPGLWGLPKRNGKLKNLEKFDASFFEIHPKQANNMDSQLRMLLEVVYEAVTDAGVNPSSIAGSNTGVWVGNSSSEVREALTKDPDTTEGYVMTGCFSSMMANRISYFFDVKGTSVSMDTACSSSTLALQNAFVAIRDGYCDAAIVGGTNVIHKPHGSLMCQQFNMLSSDGSCKSFDSSANGYVRSEAVVAVYLQRKSMAVRSYCEILNARTNSNGKTTEGITYPSGIQQARLLEDTYSECGADPCAVDYVEAHGTGTRTKAGDPQELNAIDQVMCKEGRKQPLLVGSVKSNMGHSESASGLCGVVKCAVAMQMGVMPSNLHFKQPNPEIKGLLENRLRVVTENTKLPKTIMVGVNSFGFGGTNVHVILRSSEHDKPANEIKQPTIALLTGRTENGIKEKLEYFSNCPISRFSMTNKLAEVATSKHPYRGFIIKKGENDTEPIANFEKAKPRRDIWFICTGMGSQWNGMGRHLLQIPVFAKSIDACTDALKDYNFNVKELIIGSNSTTYDNLVNSVVGLVAVQIGLIDLLRSIGIRQSGVIGHSVGELACSYADGCLTLEQTIQIAYLRGVCIIEAKLPVGAMAAVGLTWEDCEKLCEGGEVAPACHNSNNSVTLTGPKDAITTIVEKLQKEKVFARMVNTSDIAFHSKDMQLVYPRFLNEIRKIIKEPKKRSKNWISTSIKKFTASYSHEENDIETLSCSAEYHANNLRNVVRFHEGVQKMPSDVIVIEIAPHALMQPVLKKSLPLNCDRVVLADRKEENGIQTLLKGLGKLHCLCVDINLEGILPRRPLPTPKELLQFPNDWDHAESWYVPGPEVFTQHKAGITNFILDFSSDSENSYLSGHVIDGRAILPAALYIQLAWKSFAKYHQVDMAGFPVQFNKVKIQRATTLPVSGKIEFVVNLIPTDNSFQVSENGNIVCLGKLQKFEGSIETFQKVQENCEKILTQKEIYRKMRLSGYQYKGKFQAIRSATQNGQYAEIPFDGNYVTFLDGMFQLELVETPRQELKLPISIGGIKIVPQTLESGSDEIVIPVMKRNFKKVVSSGCCEVSEIETVVATRRGQTEQPLLKKYTFVPNIETEVAEQDDVVQLYAKVLEEYINKFFTSSPSPSKTTNNNGLGKNFDFYDFERSVANVHLLRMNNVLLRNKSKEEMVKEHISDLVFDPLLNYCVSNTNCMATTLDVFLENADNYVRVAEIPNTYFVHHLREIITQHLDSDTTIEYDYSPLGFQEGELSSWDSWSHFKPPPSLMNLDLIVTHRLFQQGEKAAKQVLQNAIACVSANKGFILLHEITQQTLAQNMWKKGSVIELVQNIIFEQIKKSLKDLNLEIIVHKSDEKLGSHLLLCRSQIALRDNRIGITVDHSNGFSWVEELQESVANDAEEIWLIGKKTNSGLAGLMKCLRKEPGSKQIRCLIYDGDNLPISMDEIIKRNLTFNVFESGQLGTFRHTNIERQTQVKVNRAWVKQTVQADISTLKWITMQETSSEPLECAVAYASLSNKDVVMASGKLQEDTLADNPEWFDMFFGTGFSGFNEKNEKVMGIVQTGGLATHVQIETTYLWKVPDQWSLCDAATVPYAYCIAFYAIVEKGRIRKGERVLITDGESAFAEAAIGIAVGAECDITVTVSSEETKAYLKERFMGVPNLKINDSKTASLDYLMTKTNGRGMDLVLTNTTSTIRQNAFRSISKYGRIIEIENYETSSDVKSGSMHFRATASYCSVTPECLFDDAMLDREQLTNFLRDGINTGIVKPIRRTIFSKYQIQDALRQLTKEQDGRVTLIKVKDTDSEELYRGSIYNTNSTFRTTFDSKLTYVITGGLGGFGLELCNWMVERGARHVLLTTRSGANTAYQQLYIRKWKSEDVKVIISTADVSTADGAKEILTHNVGGIFHLAMVLKDALFMNQSPESFSEVCRVKCDGVQNLDRYSRELCPNLEHFVVFSSVSSARGNVGQTNYGYANSFMERICEMRERDGFPALAIQWGAIGDVGIAAEIIGDQKVGGSLPQSMQSSLKTLDVFLSQCKHVTVLSIVVAPKDTSLLVKKDSKITMPQAVANLMGIKDYKMEKQNVHIANMGMDSLMAVEISQMLERNYGFKLTGNDVQQMTFEKLEKLSANGGNKNYVRNDTEQDLFVTVHPEALIKLNDSNDVKTMPWFFVHPIGGSSLVFKDITKHLIGNGFGLNFTEKAPLTTIEELASHYLEVVGKQQSYNLVGYSFGACVAFEMAMQLSKKKETINLVLIDGSHSFIADSIQSFVDLMGDEDAKTVEELQEEIPNVKQYKAKLHNYTRLQFERASLTYENIRRETLDEEISRYSKRLEMAHFYKVKGKYPGDITLIRQKKSITHDYNLNEVCNGKVQVITQDATHENIIRAKGIYTVFSFTRKDMSEARNKFEEN
The following text describes a protein:
Function:
Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MRSEALLLYFTLLHIAGAGFPEDSEPISIAHGNYTKQYPAFVGHKPGRNNTQRHKLDIQLILIMNRTLYIAARDHIYTIDMDTSHTEEIFFNKKLTWKSRQGDVDTCRMKGKHKDECHNFIKVLLQQNNDTLFVCGTNAFNPACRTYKMDSLDTVGEEISGMARCPYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLGDSPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNSMGKVVFPRVARVCKNDRGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTNVIQINGRDVVMATFSTPYNSIPGSAVCAYDMADVANAFTGRFKEQKSPDSTWTPVPDERVPKPRPGSCAGSASVEKYKTSNEFPDDTLNFIKMHPLMDEAVSSIANRPWFLKTMVRYRLTRIAVDNAAGPYQNHTVVFLGSERGIILKFLAKMSSGFLNDSLFLEELNVYNPEKCSIDGVEDKRIVGMQLDKKGGSLYVAFTSCVVKVPLSRCERHGKCKKACIASRDPYCGWVKEETCTDISPDTKLAFEQDIEHGNTDGLGDCQNSFVALNDIPTSPQGREKSRNSLHVIGHTGFPFLTTSHTPAKEILEDRGRMLDQKDTGAPSDKKDPYMAGSPHNHHDTNGVIRESYQKGRDQLVPVTLLAIAVILAFVMGAIFSGIIVYCVCDHRRRDVEMVRRKDKETVHSRRGSMNSVTKLTGLFETQAKEPKPEAILTPLMHNGKMGTPNGTVKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREWERNQNLINACTKDLAPMASPVIPTDLPLRASPGHIPSVVVLPITQQSYQHEYVDQPHRVEMNQIAMEDQSATLEYKAIKEHLGSKSPCHGLNIVENDAIPPRVPQREASLGPPTGVPQMGKRLEVHSSAYGHDYKRGYPLSSQQKSHQGSALKKHNTNSSNSSHLSRNHSFNRVENPPPAPQRVDSIHMNAQAQAVTVSRQPSMSSYSSLPRTGVKRTPSLKPDVPPKPSLVPLSANINPNDACT
The following text describes a protein:
Function:
Involved in the transfer of acetyl-CoA into mitochondria. May also be involved in the metabolism of acetate and of ethanol.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Sequence:
MPNLKRLPIPPLQDTLNRYLARVEPLQDERQNRRTRRTVLSAENLDALNTLHERLLEYDARLAESNPESSYIEQFWYDAYLLYDATVVLNVNPYFQLQDDPTIKDTPETAAQGPYGAHTVQVRRAARLTTSILKFIRQIRHGTLRTDTVRGKTPLSMDQYERLFGSSRIPPGPGEPSCHLQTDATSHHVVAMYRGQFYWFDVLDTRNEPIFATPEQLEWNLYSIIMDAESAGSGSAPFGVFTTESRRVWSNIRDYLFHADDCTNWRNLKLIDSALFVVCLDDVAFAADQQDELTRSMLCGTSTINLDPHQHQPPLNVQTGTCLNRWYDKLQLIVTKNGKAGINFEHTGVDGHTVLRLATDIYTDSILSFARGVTKNVVDIFSDDDGKPSSSSLASAAHSANLITIPRKLEWRTDNFLQSSLHFAETRISDLISQYEFVNLDFSNYGASHIKTVFKCSPDAFVQQVFQVAYFALYGRFETVYEPAMTKAFQNGRTEAIRSVTGQSKLFVKSLLDQDASDATKIQLLHDACTAHSQITRECSQGLGQDRHLYALYCLWNQWYKDKLELPPIFRDKSWTTMQNNVLSTSNCGNPCLKSFGFGPVTANGFGIGYIIRDHSVSVVVSSRHRQTARFASLMEKSLLEIDRIFKRQQARAAKPAARTTASANTKSEDMKYLLSGYDYFDVSVSG
The following text describes a protein:
Function:
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.
Sequence:
MSESPLTGDRFRIGYALAPRSVSSFIQDSLLLHAKQRGVDLIKIDLDKPLVQQGPFDSVFHKLYDEEWKKQLEEFSILNPTTIIVDPIESIEKLHNRVSMLDADAVAANQGMKFPLIAKALLANATADAHQMFLALNKEGLNGIKPPIILQEFVNHGGIIFKVYVAGDHVKCVKRKSLPDINEEKLGNSENLIPFSMISYFADNEQSDESLAKLMEAAEMPPSSFVNEVSKQLRHALKLHLFNYDMIRDSRVENRYLIIDINYFPGYAKVPEYETMLTPCFLDIAHQKRSRENGNLDQSENNKTHEAESNGHKMDQLENNKAHEGESNGHKMEK
The following text describes a protein:
Function:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Miscellaneous:
MISCELLANEOUS: Present with 3050 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MDSVMVKKEVLENPDHDLKRKLEENKEEENSLSTTSKSKRQVIVPVCMPKIHYSPLKTGLCYDVRMRYHAKIFTSYFEYIDPHPEDPRRIYRIYKILAENGLINDPTLSGVDDLGDLMLKIPVRAATSEEILEVHTKEHLEFIESTEKMSREELLKETEKGDSVYFNNDSYASARLPCGGAIEACKAVVEGRVKNSLAVVRPPGHHAEPQAAGGFCLFSNVAVAAKNILKNYPESVRRIMILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMGKYYPGTIQGQYDQTGEGKGEGFNCNITWPVGGVGDAEYMWAFEQVVMPMGREFKPDLVIISSGFDAADGDTIGQCHVTPSCYGHMTHMLKSLARGNLCVVLEGGYNLDAIARSALSVAKVLIGEPPDELPDPLSDPKPEVIEMIDKVIRLQSKYWNCFRRRHANSGCNFNEPINDSIISKNFPLQKAIRQQQQHYLSDEFNFVTLPLVSMDLPDNTVLCTPNISESNTIIIVVHDTSDIWAKRNVISGTIDLSSSVIIDNSLDFIKWGLDRKYGIIDVNIPLTLFEPDNYSGMITSQEVLIYLWDNYIKYFPSVAKIAFIGIGDSYSGIVHLLGHRDTRAVTKTVINFLGDKQLKPLVPLVDETLSEWYFKNSLIFSNNSHQCWKENESRKPRKKFGRVLRCDTDGLNNIIEERFEEATDFILDSFEEWSDEE
The following text describes a protein:
Function:
Required for normal plant development. Required for pollen germination. Required for autophagic activity. Required to limit the pathogen-associated cell death response. May be involved in vacuolar protein sorting. Binds to microtubules. May facilitate efficient recruitment of other ATG proteins to assemble scaffolds for autophagosome biogenesis.
Miscellaneous:
MISCELLANEOUS: Plants silencing ATG6 exhibit impaired autophagic activity and accelerated senescence.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with ATG8I in punctuate structures. Localizes in punctuate structures and colocalizes with microtubules.
Sequence:
MRKEEIPDKSRTIPIDPNLPKWVCQNCHHSLTIVGVDSYAGKFFNDPPPSATQGSSIHGANSVLGSTRMDNSFVVLPRHKPPQSQGIPPRPRGASSPQPDATQSGKAMEESFVVVYKSEPVSDSGGSHNLSLEVGQNGPLHSNTSGFNATINVLTRAFDIARTQTQVEQPLCLECMRVLSDKLEKEVEDVTRDVEAYEACVQRLEGETQDVLSEADFLKEKKKIEEEERKLVAAIEETEKQNAEVNHQLKELEFKGNRFNELEDRYWQEFNNFQFQLIAHQEERDAILAKIEVSQAHLELLNKTNVLIDAFPIRNDGEFGTINNFRLGRLPAIKVEWDEINAAWGQACLLLHTMCNYFRPKFQCQVKIQPMGSYPRIVDSNNETYELFGPVNLFWSTRYDKAMTLYLMCLKDFADFANSKDQENNIPPDNCLNLPYKIEKDKVLGYSITQSFNKQESWTKALKYTLCNLKWALYWFVGNTNFQPLSATVSLPSNISAAGSLYAKRGPDSSKPSCKKT
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
Sequence:
MPVALYRKWRPQTFEEVVGQEHIVITLQNSLKYAHIGHAYLFAGPRGTGKTTVARILAKALNCAKGPTPTPCLKCESCVEIAEGRSIDVIEIDAASNRGIDEIRDIREKARLLPVRDRYKVYIIDEVHMLTNEAFNALLKILEEPPEHVIFIMATTEPQKVPLTILSRCQRFDFRRLTRDEIIKQLAKIAESEGAKISEGALRLIAIQSQGSMRDAISLLEQLLVYSDQEITEDFARNLLGLPTYEFTYKFAKALGEYNILEGYSLLQQVFQMGKNPQQFARELLQHFRNLLLLKADERIGNLLSITQEEFEELMEETKLYTMQRLQDIIDQLLILENRLRDLTNAPLVMEMILLPLFMKEETVEAQIIQTPTQPTTPIKTEEKEEKEKRGESTPGTLNIDELLDKWPQLLAKIKKRKISLEAMLREARIIEIDQEGKLVLGLPKNFSFLKERLEEKPNRALIEEEFKKLYGVPIQVKFITVEENPILKNPEKEDPKKEEKKLSTDDVKNMFKGKLIE
The following text describes a protein:
Function:
Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters. May regulate the expression of photosynthetic genes, and may be involved in chloroplast and amyloplast development.
Subcellular Localization:
Nucleus.
Sequence:
MSEGFDGTENGGGGGGGGVGKEQDRFLPIANIGRIMRRAVPENGKIAKDSKESVQECVSEFISFITSEASDKCLKEKRKTINGDDLIWSMGTLGFEDYVEPLKLYLRLYRETEGDTKGSRASELPVKKDVVLNGDPGSSFEGM
The following text describes a protein:
Function:
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
Subcellular Localization:
Cytoplasm.
Domain:
Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
Sequence:
MRLSQMLFVTLRDDPADAEIPSHKLLVRAGFIRRLGSGLYAYLPLIWRVLEKVKRIVQEEMNRTGAQECLLPQLQPSELWKMSGRWDTYTESEGIMFALRDRLERELGLGPTHEEVITAIAKEMIRSYRQLPVNLYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFHSDEASLKATYGAMDQAYRNIFSRCGLDFRPVDADSGAIGGSGSQEFMVLADAGEDEILYTEDGLYSANVEKAVSLAPDAKPSPFSGYKKQSAPNTATIAKMCQCLDCDASNVVKNVLYQAVYNSGKAVLVLVSIRGDQEVNEVKLTNELTKLAPHYESTNILSLTVPDEKEQQKWAAKPLPLGYISPGISDDYIATNKQVADKFLRLVDQTAVDLTNFATGADAVDYHVTGANWSTDFTLPKLVVDVRKALAGDRPVHDPTGELKTARGIEVGHIFQLGTKYSQAMGATFTNEQGEEKPLVMGCYGIGVSRLAQAAVEQSYDKDGIIWPTAIAPYEVVIVVPNVGDEEQMQVAEQIYTEFQAAEVDVLLDDRNERAGVKFKDSELIGIPYRVVTGKSLKQGQLEVVKRADKSVQNLAIAAVVPTLTAWIKAEKKTS
The following text describes a protein:
Function:
Component of the phosphopantothenoylcysteine decarboxylase (PPCDC) involved in the coenzyme A synthesis. Acts as an inhibitory subunit of protein phosphatase PPZ1, which is involved in many cellular processes such as G1-S transition or salt tolerance.
Sequence:
MTNKSSLKNNRKGVASNTLSGAEQANIGSSAMPDTNSTGPFSSVSSLDTPVVRKSTSPTGSQTKSIMNASGTSGAVVSNTPEPGLKRIPTVTFSDPKLGSLRSDVEQTPPNQVARQSSEKKATSVHIAAEGANQGRNLKDINTKVPKDGEASASSFSTPTSILSNADMGNNISSLLAKKLSFTGGTDSILNSDNSSDSPRKEHPHFYVEDPLHTPSVRSRSNSTSPRPSVVVNTFNPINIEREGSISKTGEPTLLESVLEEAMSPNAVSNPLKRENIMTNMDPRLPQDDGKLHVLFGATGSLSVFKLKHMIRKLEEIYGRDKICIQVILTNSATKFFAMKYMRKNKKQHNSIDTSFNSTNSNAGNITGNKKKVASLEKFSIQKTSSNSAASQTNNKQEEEKQMASTTGFPSTLGGSRTYSNSSNVVSQHPQIELPAHIQFWTDQDEWDVWRQRTDPVLHIELRRWADILVVAPLTANTLAKIALGLCDNLLTSVIRAWNPTFPIFLAPSMGSGTFNSIMTKKHFRIIQEEMPWVTVFKPSEKVMGINGDIGLSGMMDANEIVGKIVVKLGGYPDVSAGKEEEEDEDNDEEDDNKKNDTGGKDEDNDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDEDDEDEDEDDEGKKKEDKGGLQRS