lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MYQAENLLEPLLKKLIQSYTPNQDDASDSPEATIFASIVSGSCLETTTLRRVLELSLQSYISSVIECDTPKIMGAGSLLRQVYEKNVAILDSIIDAEFKLCNDTGDKGKLHRAALQKLMTSFLKGTMLESVDDKGTTLYLSLHHPQPEVRLLAIEKLQSILDTDLLTNEKTSMHDIARETLSVLITDQDQTVATAALSFPNLVSYVPINELSSFAADLLASKHTETRLRAAAAQVLCKLLDKPDCPMSCCEVLLGTIWRTEKSTVAATLLASFLPALLQRIGINTAASVEFGQKFVENVNLQQQQQSEQVQETPKDQSSPHTLMNIATIKFLGDALRTSTIFRAFVIQNAVHSKFDRARLVGILALAGEIKSVSQLDKDTLTLVPFLMKNLSEIPTTTRNPVTNIIGIIDSNRIVMSGKDAQTFAIVKIVLEIIKKLSQPASWLDSEAATQSVHTCTLKGVFLAVLAVKNQAIREHLVEKFLDLVGTRNIVSFCASLWIAANNSNIGILGLTIVKKFISSSSAKAFDYQLAIPSILLALVHADHHIRSAAMDIMKVICSEYGKLSGLQLKLSQENIYGYEYFYGSKSSEVGYLTVASAARFANQICNWQHEIIADACFLKNNIHTALRRGDEAKIKYQEDVLGFLLTNICAFGIVDAQIQLVSLLENVDSPLKLKGLFPLVESNTAIVFSEMTCADLGTEKSTKEVELVTKHATLLGLLTQSYSSAAVASLFQSRSGRYLKSFCNLLSPNTFLKISDAHKQLWCTVNACALEQITDTWISSIQVEKCQVVFTALIDLIAFGDGEISAKVKIMLKPLPLTGQAILPILERIQQHLSNNLNPSTSKRVKGQAADDNGSIVAGVALLELLQFKENMTDFGILIGPLFDILAALLNADIVQTLTEVDYFKQLLLSTLELIFKVDAEKEILSVNEDSIRIDLVVQCIRLTDNPQTHNSALLLLSTIASVAPQSVLINIMQVFTFMGANILRQDDSYSFHVIQQTLQTIIPALMQHLDGDDFAGVKPIMEVFVQALPHIPEHRRLRLFTLLVQILGVDKHLGSMLALIQSNSIISSYLVAQRASDANQAISFGLNLLQEFSHHDQLKALIKISVFQQSLPNQNVQCNSPLLEPNSEIKTVRRIKLQLTNFVSQALKSKALIHSATAEVAKSSENFSDLHLKLIELLLVEIDTTSLFATEVQIRPGSSDAKFSKLYLNALQEALGLVNNLLPLAMFMHVTGELLKRKEEGICHRSLVMLRQRLVSLEGTDELDHQVFVPVLTILVSMLKTKSTKAKILENKQLVMECISSTADLVGKNIPKVITECFTALLADHCIRSENDNIASSTIVCLSSLSVVLGPRIVPFIPTLLPTVIHNGQAALASNADTRSIVVSAVFGFIVIFIETLPQFVSPYLGDLIGFVAEPRIESMTPRITQLASAISSGLARHISARIIFDPMSKQLTTALKASEFSTVSICKLLADVIYNTPQPALIDCIKPLGAIMIQGFGYRCSGPGAPVAPKVTF
The following text describes a protein:
Function:
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Binds to the flavoprotein subunit SDH1 in its FAD-bound form, blocking the generation of excess reactive oxygen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit SDH2 into the SDH catalytic dimer.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLCAIKSTGYRYPRTGALNLLRGRPFNMATRKITTERIPGPPKLPREEQEEFERLQRIATSQEAIDQYNAQATGDRTKESLNSPLLTKNDIGSFSPEFSKTIPEFEGDVNPKTGEVGGPKQDPLRHGDYSFNGRVTDF
The following text describes a protein:
Function:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Sequence:
MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLVEHQAHDILT
The following text describes a protein:
Function:
Component of the glideosome complex, an inner membrane complex structure involved in parasite gliding motility and host cell invasion. During the asexual blood stage, required in schizonts to recruit MTIP and MyoA to the inner membrane complex where they assemble with GAP50 to form the glideosome complex. By regulating the formation of the glideosome, plays an essential role during merozoite invasion of host erythrocytes.
Subcellular Localization:
Inner membrane complex; Lipid-anchor. Note=Localizes to ring-like structures during the early schizont stage. In fully segmented schizonts, localizes around the periphery of each merozoites. During merozoite invasion of host erythrocytes, localizes to the interface between the merozoite and the erythrocyte membrane.
Sequence:
MGNKCSRSKVKEPKRKDIDELAERENLKKQSEEIIEEKPEEVVEQVEETHEEPLEQEQELDEQKIEEEEEEPEQVPKEEIDYATQENKSFEEKHLEDLERSNSDIYSESQKFDNASDKLETGTQLTLSTEATGAVQQITKLSEPAHEESIYFTYRSVTPCDMNKLDETAKVFSRRCGCDLGERHDENACKICRKIDLSDTPLLS
The following text describes a protein:
Function:
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
Sequence:
MSLAEFDADVVVDARDCIMGRVASNVAERALAGDRVAVVNAEQAVITGTEDDVFSTYRTRANLGSDRGPYYPKRPDGIFKRAIRGMLPYKQDDGREALDSVRVYVGNPMDEDGDVLDGTSLDRLSTIRFVTLSEVSEELGANVTW
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.
Subcellular Localization:
Nucleus.
Sequence:
MCSVFESLDMDNFQGDLTDVVRGLGSGHMTSSPGPPEGPFAINFHVDFPSVANSQMNPFGDPFVSMTDPLLSLPANFSGAGDSKSNNSFAVFPNTTVDDHVKNQCSVFPRIRISQRNIIQDASKCNSPAMATSSVTAASPWGMINVDSPNSPRNCLLVDNNNITSSSSQIQISSCPQNFGITRRKGQGKKVVCIPAPAAASSRSSGEIVPSDLWAWRKYGQKPIKGSPYPRGYYRCSSSKGCPARKQVERSRTDPNMLVITYTSEHNHPWPTQRNALAGSTRSSSSSSSNPCSKSTIATTSALSRVSQNKEEPNRSHLPFSSTPPPYVAKAVKEEDAEERKDNMEFDDVDDTYRPEFQHQLGDFFADLDELEEDSLTMLLPQGFSGDNSGGGNLDNKRMIPDVFSDFFDDDSPRSL
The following text describes a protein:
Function:
Binds selectively to the HSP27 20E response element.
Subcellular Localization:
Nucleus.
Sequence:
MSPPKNCAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQKCRLRKCLDIGMKSENIMSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNLDHYSGSQDSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPDRASQAINRLMRTQKEAISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGVEIISKIVDSPADVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRILNRILSGGGANAAQQTADRKPLLDKEPAVKPAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGVGEQPSTSSSHPLPYIANSPDFDLKTFMQTNYNDEPSLDSDFSINSIESVLSEVIRIEYQAFNSIQQAASRVKEEMSYGTQSTYGGCNSAANNSQPHLQQPICAPSTQQLDRELNEAEQMKLRELRLASEALYDPVDEDLSALMMGDDRIKPDDTRHNPKLLQLINLTAVAIKRLIKMAKKITAFRDMCQEDQVALLKGGCTEMMIMRSVMIYDDDRAAWKVPHTKENMGNIRTDLLKFAEGNIYEEHQKFITTFDEKWRMDENIILIMCAIVLFTSARSRVIHKDVIRLEQNSYYYLLRRYLESVYSGCEARNAFIKLIQKISDVERLNKFIINVYLNVNPSQVEPLLREIFDLKNH
The following text describes a protein:
Function:
Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system. Cognate E2 conjugating enzyme for the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSDNRSRRIAKELADVQQDKQAGIQVWTINDDISHLKGMFRGPEGTPYEGGYFVVDIEIPIDYPFRPPKMNFDTKIYHPNVSSQTGAICLDILKDQWSPVYTMKSALISLQSLLCTPEPSNPQDAQVAQVYLQNYQQFVRTAREWTSSYAAAPAGVDLDAENTEFGGIDPNIITNLQQFGFSTELIVRVLQREHIKSQEDLKDYPNGINGILDQLLH
The following text describes a protein:
Function:
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
Subcellular Localization:
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Domain:
Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
Sequence:
MEVKELERDKNRVVLEYVFGAEEIAQAEDKAVRYLNQRVEIPGFRKGRIPKNVLKMKLGEEFQEYTLDFLMDLIPDTLKDRKLILSPIVTERELKDVTARVVVEVHEEPEVRIGDISKIEVEKVDEEKVLEKYVERRIEDLRESHALLEPKEGPAEAGDLVRVNMEVYNEEGKKLTSREYEYVISEDEDRPFVKDLVGKKKGDVVEIEREYEGKKYTYKLEVEEVYKRTLPEIGDELAKSVNNEFETLEQLKESLKKEGKEIYDVEMKESMREQLLEKLPEIVEIEISDRTLEILVNEAINRLKREGRYEQIVSSYESEEKFREELKERILDDIKRDRVIEVLAQEKGISVNDEELEKEAEELAPFWGISPDRAKSLVKARQDLREELRWAILKRKVLDLLLQEVKVKVVEPKGEGDDSEGKEDN
The following text describes a protein:
Function:
May be involved in the coordinated dissolution of the cell wall matrix during abscission and in the secondary cell wall formation in xylem vessels. Prefers arabinoxylan, but may also use pectic arabinans as substrates.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MDMESWKLLRSVCVLSFLLGSCFVYQSLRVVDAQEDPKPAVTLQVDASNGGGRPIPETLFGIFFEEINHAGAGGLWAELVSNRGFEAGGQNTPSNIWPWSIVGDHSSIYVATDRSSCFERNKIALRMDVLCDSKGCPSGGVGVYNPGYWGMNIEEGKKYKVALYVRSTGDIDLSVSLTSSNGSRTLASEKIIASASDVSKWIKKEVLLEAKATDPSARLQLTTTKKGSIWIDQVSAMPVDTHKGHGFRNDLFQMMADIKPRFIRFPGGCFVEGEWLSNAFRWKETVGPWEERPGHFGDVWKYWTDDGLGHFEFFQMAEDIGAAPIWVFNNGISHNDEVETASIMPFVQEALDGIEFARGDANSTWGSVRAKMGRQEPFELKYVAIGNEDCGKTYYRGNYIVFYDAIKKAYPDIKIISNCDGSSHPLDHPADYYDYHIYTSASNLFSMYHQFDRTSRKGPKAFVSEYAVTGKDAGTGSLLASLAEAAFLIGLEKNSDIVEMASYAPLFVNTNDRRWNPDAIVFNSSHLYGTPSYWVQRFFAESSGATLLTSTLKGNSTSLVASAISWKNNGKDYIRIKAVNFGANSENMQVLVTGLDPNVMRVSGSKKTVLTSTNVMDENSFSQPEKVVPHESLLELAEEDMTVVLPPHSFSSFDLLKESAKIRMPISDSSSHQKTTTV
The following text describes a protein:
Function:
Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1, SLC16A6 and SLC16A7 to the cell membrane (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Synapse. Note=Localizes to the neuromuscular junctions.
Sequence:
MRALPGLLEARARTPRLLLLQCLLAAARPSSADGSAPDSPFTSPPLREEIMANNFSLESHNISLTEHSSMPVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYLVPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQIEQLKSDDSNGIENNVPRHRKNESLGQ
The following text describes a protein:
Function:
GTPase-activating protein for the ADP ribosylation factor family.
Miscellaneous:
MISCELLANEOUS: Present with 5350 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Golgi apparatus. Note=Associates with the Golgi complex.
Sequence:
MSTSVPVKKALSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVKSVDLDTWKEEHLVKLIQFKNNLRANSYYEATLADELKQRKITDTSSLQNFIKNKYEYKKWIGDLSSIEGLNDSTEPVLHKPSANHSLPASNARLDQSSNSLQKTQTQPPSHLLSTSRSNTSLLNLQVSSLSKTTSNTSVTSSATSIGAANTKTGNRVGEFGQRNDLKKSILSLYSKPSAQTQSQNSFFTSTTPQPCNTPSPFVNTGITATNNNSMNSNSSSNISLDDNELFKNVWS
The following text describes a protein:
Function:
Probable transcription factor that is required for uterine and neuronal cell fate decisions. Controls genes required for the specification and differentiation of O(2) and CO(2)-sensing neurons and for maintaining URX sensory neuronal cell fate.
Subcellular Localization:
Nucleus. Note=Localized to nucleus during interphase.
Sequence:
MSRRRKANPTKLSENAKKLAKEVENSQEENDCDMLAKPQTPTIIIPGHMDDTPNPAGSPHDASIKSSSSTISDHTSTSATTGISDFPDILAQTEHGCSVLIDGNHLREIINSVDTQDGKQDLLSDVIRQLTSIKERLTNDESPVKDDLKEDPDDMSPMLHAGNFDSEMLLRQHELMQHQQQQMIIANMLKATQSLPLLFNGGLNYEAILNNPVLNATIAGHLPNPLASNISLLQKSISAKLAAAGNMQTVEKVETPLNLSKDTPSPTAIPQSPLSGFRLPYSLGTNYGSDGQLFNNCSPNSSGKSTPGNTSVTSEVATPRPQAKSPNHIKRPMNAFMVWARDERRKILKAYPDMHNSNISKILGSRWKGMSNSEKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCVIDGKKVRVNEYKTIMKTKKDLMWGDEPGFSQPSDLQMDLASHVNLLNDLTQHHHQSHLLQTAE
The following text describes a protein:
Function:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification (By similarity).
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MLTTTIPQFPDTKLYISLFRNVSNAPEIVDSLAELPYSIIDARTLLSREQLLSAVYRAMLEKHCNKLRTRNLHTEVLLCLSPTSNVMSQIGDAMKRFGIKKDSTSVVLVKAVTGDETFDPKGFSEVIRGEELEFSDTALRESADIDTIRENYKLKCFECERLEELSAALVHAIQLRGL
The following text describes a protein:
Function:
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB subunit has 5' -> 3' nuclease activity but not helicase activity.
Miscellaneous:
MISCELLANEOUS: Despite having conserved helicase domains, this subunit does not have helicase activity.
Sequence:
MSLRFIYGRAGSGKSQYCLNSIKNRIEEDIDRPLILLVPEQFSFQAEKNLIEVLDEKTGFKTQVLSFKRMAYRVFNEVGGITAKHMNESGKSMLLYNIIEDNKNNLKVFKKAAKRQGFITTISDIITEFKRYNITPEIILNNLENIEGDNLKYKMEDLALIFSQFETRLHKNYIDNEDDLTILAEKLNKSKQFDNAEIWIDEFSSFSPQEYSVLEKLLLKSYRINITLCTDYLNQGRFVDTTDVFSPIKNTENKLLQIIEDNNIKLDKPIALNCDPCARFKNSAELQHLEKNMFSFPYKEYKNETKDICMLKTLNQFTEIENTAKDIIKLCIDKGCRFKDIAVITGDLEGYENIISSVFLQYNIPFFIDKKREINNNPIIVLILSALEVLSKNWTYESVFRYLKTGLLDINNEEMDILENYVLANGIKGYQWTNDKPWEHKFFSNYELEDQVEKELLAKINDIRYKAMEPIVTLNKNFKSIDKAKEFCEVLYEFLCNINLPDKIQNMIEDFKVEGEIEKASEYNQIWNIVMEVLDQIVEVIGEEKISLKEFFKILQTGLSEYEIGLIPPTLDQVMVGSITRLRSHNINTLYIVGVNDGIFPSPLKEEGILSDDDRKFLGDKGLEIAKDTKSIAFEEQFLVYSTLTTPSKYLRLSYPIADGEGKTLRPSIIISRIKKIFTNICEENDIVKLNGEEEELKNISSAKPTFNYLISNLRKDVEGAKIDNIWGDTYKWYLENEFWIEKLNRLIKGFDYTNQSKYIETKKIRNLYGKPLKISVSRVEKFSQCPFAYFVQYGLKAKDRKIFNLSYPDLGIFMHSILEKFSHELEKQGLEWDTMDLNWAEEEIDKLINEELDNKSLDILNSSKRYEYVTKSVKKILKRSIWLIGEHIKRGNFKPSYYELSFDIDGDYPPIAMELHSGEVVNLIGRVDRVDLLQKDGATYLKIIDYKSGAKEFKLSDVYYGLQLQLLIYLDAILTELAERSGINGEPGALLYLKLDDPIVKNTVDMSDEEIEKSIIKNLKMKGLILNDPNVIRDMDNIISGISDIIPVMVKKDGGVSEGRSSVATKEEFETLRKYVRYTIIEICEEMLEGNIEIKPYKKKDGSSCDYCIYSSVCKFDTNIRGNKYNILIDKKDEEVWDAIKKKLEYKNI
The following text describes a protein:
Function:
Antiporter that mediates the exchange of sulfate and oxalate against chloride ions across a membrane. Stimulates anion transport activity of CFTR (By similarity). May cooperate with CFTR in the regulation of chloride and bicarbonate ions fluxes required for activation of the ADCY10/PKA pathway during sperm motility and sperm capacitation. May play a role in sperm tail differentiation and motility and hence male fertility.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Note=Located at the annulus ring structure within the sperm cell.
Sequence:
MQTERSLQSFSNRYTQIPFVYDVKRSVYNEENFQQEHRKKGPTSGNVDIDITTFKHHVQCGCSWHKFLRCMLTVFPFLEWICLYRFKDWLLGDLLAGLSVGLVQVPQGLILSLLTRQLIPPLNVTYAAFCSSVIYVIFGSCHQMSIGPFFLVSALMINVLKDRPFNNGHLILGTFVKDDFSVPTFYLSYNRSLSMVASTTFLTGIIQLSMGMLGMGFMATYLPEAATSAYLAAVALHIILAQMTCILGIMVSFHAGPISFIYNIINYCIALPKANSTSILLFITSVVALRINKCIRITFNRYPIEFPMELLLILGFSLLTSKITMATENSKMLMNMIPYSFVFPENPEFGILSRVVLQALSLSFVSSFLLISLGKKIANFHNYRTNSNQDLIAIGLCNLLSSFFKCCVFTGSLSRTTIQDKSGGRQQFASLVGAGVMLLLMVKMESFFHNLPNAVLAGIILSNVVPYLEAIYNLPSLWRQDQYECIIWMVTFSSAILLGLDVGLLISLAFTFFVITIRSHRTKILVLGQIPNTNIYRNVNDYREVILIPGVKIFQCCSSITFVNVYHLKQKVLKEVNMVKLPLKEEEIYTLFHESETSIAENKLCRCFCDCEELEPEIRVVYTERYENRQEQDSSINLIRCSYLGSGDSSQVTSEEQIPYTVSSTSQRNIVQSYEDTEKAWLPNSPPRNSPLPPPEASESLAQSRSRSIIMPYSDTSVQNNTHTIILDFSMVHYVDNRALVILRQMCNAFYNANILVLISGCHTSVVKSFEKNDFFDEGITKAQLFLSLHDAVLFALSRKFSEPSDLSMDETETVIQETYSESDKNGNLSNLRLKTGKAIIEGSQHASPGFTKNLKPGKDDLEFDLELDPMLSFEQSSGMDLNLDLDLDLDQSELDPGSELDSEIQAKPELELESELETDAQTEPETEEEPELEPEPEPEPETEPEPEPERERKTRTRSQSPWRNYFTAYRFGSSNSQSRAPPQTRPEKRKPHNYPNSP
The following text describes a protein:
Function:
Plays an essential role in chain termination during de novo fatty acid synthesis.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MHFVYVQNFSRNRTIKKKEKRPSVPTKVKKKRGSIHTYSIILWTSTWLLLGKASTEPQIKQIKKSQFGNLIGNTKDSSLLLLLSSPPPPPPFPSSALPRPPVLSAIVSDRGEASLHTASGTLADRLRLGALVEDGLSYKEKFIVRCYEVGINKTATVETIANLLQEVGCNHAQSVGFSTDGFATTPTMRKLHLIWVTARMHIEIYKYPACKWVMMNQDTRRLQKVNDDVRDEYLVYCPRDLRLAFPEENNSSLKKIPKLEDPGHYSRHGLMPRRADLDMNQHVNNVAYIGWVLESMPQEIINSHELQTITLDYRRECQQDDIVDSLTSVEEVENGGKAVPELNGTNGYISSDKEDTRQFLHLLRLSSDGLEINRGRTEWRKKQQRRG
The following text describes a protein:
Function:
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
Subcellular Localization:
Membrane; Single-pass membrane protein. Membrane; Single-pass type II membrane protein.
Sequence:
MSRGDVVTAAASPYAGGCLAADSVYGIIRQFIGTSAGSTVAIDNKIEQAMDLVKSHLMFAVREEVDVLKEKITELLDRISQLEYFYITVLRDPVTRFRSEWRRFHQNRGWHGARPHPCSDDSPADAPTCFEARRPDNVSWAEFLACPANPALNRQTHMLADHGLVDGCTRNGSVDEPLAGGDRDTVLLASAKRNLRRMAFFGLAEFPRLSQSLFEATFGVRFRRTTVRQRGFLRSRWKGRPRGPRGDAEAVASANVLDVRLYGYAKELLFSRFRALKESNPDAEEDKAAGEGNWAEEEDFFDNL
The following text describes a protein:
Function:
Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate, oxidizes D-glycerate to hydroxypyruvate.
Sequence:
MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL
The following text describes a protein:
Function:
Plays a role in vesicular protein sorting.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MAFRIPEDDGTDECVVTLRGPVLTAAEEQKKWLQEALIAVDRKAAIMRNSMESQDSMAVVIRAAAQMLDELRTNLLEPQNYYELYMKVFSMMEVFVAYLEDEQRAKRHTLEEMYERVQFCGYIIPRLYLLIAAGAVYIDAGDQPALEIARDLVEMCKGVQHPTRGLFLRHFLLTMMKGKLPGDQNRRVSDVGNGPAGEGQEEYPHKEDGGTVADTANLLVQNFKEMNWLWIRMEAGSYVNRNGGSTNSVTACSPTTAALPATSLPPAASTAASSRSSDAATRPGSPSRSLRAARRTQQERRAMCVLVGMNVVRVAQLDGISRDVYASTILPQLLSIMVRYCEPLAQQYLFEVLIQVFPDEFHLFTIDKLFGAINRTVPGVEVSELLRSLMERLCKYAVAVQEGVTEVSSPEEEAKLRDVFPMLLNQMSCMSVSYSAQRSAATVIKRTSTVPPPTPMMLGTYVTTMRHLVNVVMTLYGKSAKRRFMSLSNIVDVVASKFPSAPADSSESKESSGVVETAVASAETLTHVSISPAAALAAGQFLVHIITESCATVQEVMAMEGIAALTSCLPFLQRREVAMAVCEVALRGSTAAPVLPSVSKAASSGAGGGGWKPTVVVTVPPPSPRPITALEDVARLFELLDPILVEQPDAPSDPRLIYKYNPAVEFVDEQNLVCRMLHLLANDDPAVYAKMLTGVRKVLLQGGARRIPLTYPTLMTLHRRAALRLYAQYQRLSSSSAKSDEGERDGDEADTAAAAASQAMKAIRKCFSHVHSGDSKGILEVFAVEAPTEALKEYLFCSNTADVCEQSETSYTLYVEALTLYEGHVEGHEQIDVLVACVNALCQMRSMPEENYEVLAAKVCQYASKMLKKHDQSYLVAVCAALFAKKQLSRENQQRVQECLRRSLKLAGQVLALAQLQLYVQLLNIFLHFFTSKSGYLVSVELVNELIEKISEASEVQRSEVGGDGNNSTADDDDSDNAANMFAKIRLVYRNITKYIRSRQSAEERWSEIDV
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.
Subcellular Localization:
Nucleus.
Sequence:
METVGIFCRSLFHASWTLLQIKEEMGKQGPCYHCGVTSTPLWRNGPPEKPVLCNACGSRWRTKGSLVNYTPVRARAEGDEVEIDDRRGGQKMMMINGMSMNKKRKPYQENFTVKRTNLEFSNGFKKRSLEEEASNNRSSSGSVVSNSESCDQSNVWETSFAACKKRTCVGRPKAASSSVEKLTKDLFSILQEQQSSCCVSGTSEEELLFENESPMVIGHGSVLLIDPHEDSEASSLLVESSKSSSIHSHNFGGKAIKQEQLKRTKSQVLGRHSLPLCNIDLKYVFNFDEFKEKFTKEEQQKLMKLLPQVDLPDSLLSMFESSQFKENFSLFQQFVADGVFGTSSSSGSKLEEFKTLAKLALSDPNKSHMLESYQMLKEQRKGIEDSSRVSNQTPSDNHSLVTIERPCESLNQNFSETRVVMKSPKEVMKIRSKHIETKEIIENSVSSLNHMSYGGSMVCGGYEDNDNSAQDLLLDVPSNGSFPQAELLHMI
The following text describes a protein:
Function:
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Subcellular Localization:
Endoplasmic reticulum membrane.
Sequence:
MFWPKEWLPNEVGFRHVRLHSYGYNSDWTARKGRALSIHDFGQALLADIYGGPHLRKNGDTPIVLVAHSMGGLVAKKAYLLATRDPMYASIAQRIHTIYFLATPHRGADSAQTVKLLLSSAGYGAKGFVDDLLPGSGTLDQINDEFRHHCGNVHLRSFFEGVPTSFAGIRSCLVVDKDSAVLGLPNETSRYIEADHRRICKFESPVSPNYTILQQSFLTTIEDIEADSGYNPKDEHRSQMKLVSSFLHVDQRPDATLLELKGKEHQGSCHWVTEERAFQDWMQEPFNLESCDPLETARQTDNKKVLWLNGRPGTGKSVVAGHVIRFLEACNFDCSFYFFRRNTQAATTVSGLLLSMAYQMAQNNFDIRRSIAAMAEDGQRLSHADHHMIWSKLFLERIFRTETTRPQFWVIDAADECSSKGLAAFISMISNLSCKVPIRVFMTSRPGGQLERLLHHEKTQYSVIRTGQKGSMGDIELFVRGRFPIEASQMLIDEILARSNGIFLWASLTMTKLEDCYTIEDKQDALRGIPSGMDDFYLRIVESVVDSPSCELAKCILTWVICAPLPLRAEELAEAVKRDIGRTLDALPGQLPSIAGHLIEVDDNHHVHILHLTTSAFLTQKRDEPSFWIDKQAAHGQIAQVCLELLCGTEFAPPKSRRAGAASKATPSPLSDYAATNFSYHLMHSSSACDTSLVLLDKFLRSNVLTWIERAARSGDISILYHTAQRLKAYLARRAKYQPPLSVETQTISGWITDMYHIAAAFYSGLLSSPSSIHFLIPHLCPPRSMIHSIFTKPSKLLRITGTFEEEWSDKLTCYLFAEEALSLGFCGRYLAVGLRNGNIELYQTGSRAFGSAQTLKHGKRVQRLAFNQSSTLLASFGARQVTVWDIRRSSSSAFQAMWSQRLEFAPSEIKFSPNDEILFLANPQQSSFSAFDVTSGSIKEPLLLHAPPGSPPDSDSSDEEAQRPKVWTPAQLIRLDESQKLAALAYRDGTAAIWNLEDFGKIGCFEKEGFEGVYPAPPILDLIFNPVFELELLAISYKDEELVICNPWSLMQQASYRLQYSLGILAATSDGRILAGGDEVGAIHLFSFETLQPLYRIERPDERFHIPGLVFSSDNLRLFDIRGQCCNVWEPLVLIPRGGSDDSSSEPHSKEVANNDTVAPSAHFFHWGEAITTIESAFDGIVVFVGRQDGTVDICESATGECIEKLKLHDSHAPIHQVDWNNEKKTLFSMDISGRCILTRLEFDPKKRTQIGVTKCLDHKEQTGCPFQAILSPQGLSIFLHTLAGIKVVAAMADSIEGTIVENNNFHWGSSDARARWVIHPSNSSHVLALRDKRVHVFDWSTLQPLTTADGILADKITWQTDLPWISRSGSTYVGCVSTVLSTPSCHFTAFDASQVTPETKSLALPTRNIEVVGLQTVAGLIRSTLYFLDTNGWVCSISLKNLDRTSYFTRHFFIPPTWHTGGNVVIKVISKTAVALARGEKLIVFHGFLEFGEKVLFDEKVIIS
The following text describes a protein:
Function:
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment'. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity.
Subcellular Localization:
Chromosome, telomere. Nucleus inner membrane.
Sequence:
MESENTKNTQEMKTDLKLLLECLKYHMGNPLTQKEVLITIHSVCKQNSDAGIYFREIGGLMFIIDLAKSSEHSMVKEAALYTLGSIAEENVYCQQSLCTSELFQDLTMFLTNDDSNTNLKRMSVYVLLVLVSNNRNGQTLVREMGCIEVLSEMFKTVLSNYELNLSDNNDFQSYLLWSSVCSTLCVCVNNPQNDENQLLCCSLFPYVNEWLMNCMKSEIIRPICSFIGLTLANNTHVQNCFVSSGGLDVLSQVLVRLESDSHSTFSSAKLAVVVIKTMDACITDNSAAFAVILSKYHIVSTLMALLLHESLDSGEKFSIILAIGHCTEDCEKNQYELLKNNGLPMMIQALVEFKNEDLNKAATYVLLNCKKITRKLSQSLGQNSFGENETELKDINEKETLGEHWQAANEIICRLKRFEKGMKEQQEDSSEHCMDNTPSMKVNIQTNSKHLCGDRIGGTRAEDKDTNQTRQLHSSKPSGIVSKACANENQPKTLIKDTNPVNPLYRAKGQDKILPKTTPSCAQNLNEEKTFDQRDSVSQSSDHVLKHLTHTVKNRKQQVPETDPFTLCLDIIDKEVGFQETDNCSRMLKYRCPGCIVVRKLLNSRNFSKLLHSCAYQCDHHKVIMEAEDKYKNELRKAFICAKRILLTPCRRRQLSKESTASEEIKIVHQKQNSKKLPGLEAQAFNTSIPEAKERRSPVPGQHGLHKKRRIRKNFTKEEVNYLFHGVKKMGNHWNLILWSFPFQKGRRAIDLAHKYHKLIKGPSCGGIQSLDS