lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
Sequence:
MDGFIVIDKPIGLTSHDVVARVRQTLRQKKAGHTGTLDPFATGVLPVAVGEGTKAIPYLDESTKVYRATLILGAATDTQDHTGQVVHAGDWRHLEPQSVRDVVSSFTGKLSQLPPMFSALKRDGVPLYKLARTGREVERERREIEVFSLVVDSIDLPLVTFTLSCSRGTYVRTLAHDMGERLGCGAHLTELRRLSSGPFNLDRAISLERLKELAEAGNLADVLVSPSDALGHLHALPLTAQGAERVRRGMPPCREDVEHGAGTGIPAGTRLRLLRDGIVVAVADSLAGLWSSDTKNLRLLRVFN
The following text describes a protein:
Function:
Involved in the regulation of plant growth.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing VUP2 exhibit severe dwarfism.
Sequence:
MENSVNNCVRQRVFSNHQIRMIHEEEDHEESSWIVYFEDIDHDDEMVETEGEMTHYYDNDSSMISDAASPVHTTKINNVVRRKANNINTNPKKRRIIHQHKEEEEEELQKGEEEEEDEEDTASSPSNKTKIFSVLDHANDNTRYGKTMDNVTSEEIGCITETGSKIKEIMNEEFSAELKKRGLCVVPLSMLSNFIA
The following text describes a protein:
Function:
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved (By similarity). Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion. This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7 (By similarity).
Miscellaneous:
MISCELLANEOUS: Some rotavirus strains are neuraminidase-sensitive and require sialic acid to attach to the cell surface. Some rotavirus strains are integrin-dependent. Some rotavirus strains depend on ganglioside for their entry into the host cell. Hsp70 also seems to be involved in the entry of some strains; MISCELLANEOUS: In group A rotaviruses, VP7 defines the G serotype; MISCELLANEOUS: [Isoform 2]: Produced by alternative initiation at Met-30 of isoform 1.
Subcellular Localization:
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Sequence:
MYGIEYTTVLTFLISIILLNYILKSLTRIMDCIIYRLLFIIVILSPFLRAQNYGINLPITGSMDTAYANSTQEETFLTSTLCLYYPTEAATEINDNSWKDTLSQLFLTKGWPTGSVYFKEYTNIASFSVDPQLYCDYNVVLMKYDATLQLDMSELADLILNEWLCNPMDITLYYYQQTDEANKWISMGSSCTIKVCPLNTQTLGIGCLTTDATTFEEVATAEKLVITDVVDGVNHKLDVTTATCTIRNCKKLGPRENVAVIQVGGSDILDITADPTTAPQTERMMRINWKKWWQVFYTVVDYVDQIIQVMSKRSRSLNSAAFYYRV
The following text describes a protein:
Function:
Plays a role in tubular endoplasmic reticulum network formation and maintenance.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Localizes to three-way ER tubule junctions.
Sequence:
MGWFFQKKKEFDFGGELDRLEMKLEEAQYNIDNIQSQKKKILFRYTVCSLAIYTIGMAVWASRSSILFQHPLFSKLFRISLYILGVFSLYMFRWAIAWFCEKRLSRARMNLHKLNAEKRKILDALKSRKEYFETQALLEKYGEQPTLAQKKLSNAAAAKSVPGSSSSSSDPMHPQHWYDRVLEGLVGANENSENNREALICSHCFHHNGLASYGEKASDVRYVCLFCKAWNGPPIDKSLPSSEMDSNLQTNPSSISKGKKNNSNNTTQKGPNIISSPQVINASSPVRKAGKKKSKKALPTSPLSSSSPDASYNSVSDSFHTVAASVPESLTPTK
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Sequence:
MRGEDEELVDQKKYLEERCKPQCVKSLYEYEKCVKRVENDDTGHKHCTGQYFDYWSCIDKCVSTRSQLALYRLSLSSQRRTNFLWNMHLQVASKLFKKLK
The following text describes a protein:
Function:
Has a role in cell morphogenesis and cell fusion and may antagonize the PKC1 pathway.
Miscellaneous:
MISCELLANEOUS: Present with 1350 molecules/cell in log phase SD medium.
Sequence:
MAGFSFAKKFTHKKHGKTPSDASISDQSREASLSTPPNEKFFTKQETPQKGRQFSQGYHSNVNKTSSPPMFARKQVSESRIQPSAVPPQQRNVSGPSTTLHKQLSKQREYTVWNRIKLQNSPFPRYRHVASAYVTDKNQIYVIGGLHDQSVYGDTWILTAFDNATRFSTTTIDISEATPPPRVGHAAVLCGNAFVVFGGDTHKVNKEGLMDDDIYLLNINSYKWTVPAPVGPRPLGRYGHKISIIATTQMKTKLYVFGGQFDDTYFNDLAVYDLSSFRRPDSHWEFLKPRTFTPPPITNFTMISYDSKLWVFGGDTLQGLVNDVFMYDPAINDWFIIDTTGEKPPPVQEHATVVYNDLMCVVGGKDEHDAYLNSVYFLNLKSRKWFKLPVFTAGIPQGRSGHSLTLLKNDKILIMGGDKFDYARVEEYDLHTSDIDMQRGTIVYTLDLARIKDLCPGVMDVPTDTPTPRNGNLDLATPVTPTSHQTKNMNVPISAAPLASAPSPAPKDFSDADRLNREVHNRNVSTEHQNQSHPVNSESHLIAEPNILTPYVPSESSQTPVMKITSNKPFDTPTIQKEPDLSETMDPTVGNQRIPSSIYGDNLTPANQIKNNSPILETLPSNEIKTPQNGNIEEIKHLPDADEKIDSTTTFDQEINGDKLGTSSMSKVEEDGNVADEDDEIGVAQMASSPSKDQFKIKHYNESSELSQNNTEIDKLSEPVDITIKKSDTAGHDSANHVIDASDEKNVSPMGDVPTDTKNEEASVPINRDATTEVVDRALFEKLRSELQSLKELTHEKALEAGAHIKELETELWQLKSQKNSGTTKEIDELDSVRLQSKCEILEADNHSLEDKVNELEELVNSKFLDIENLNEVIQFQNEKIKSLELEPNYKEKLEELQIEHENLSRENERLKNESKQHNEDIINNVANYSSQLGSLISHWKENRANSSFLESSSSLISVSDENGEKTVGEPYGDQSRHHRVVINKLTNRLDDLLERSQELTISKEKLSSEYHALKMEHSSLSQDVLVKENEIKKIQNDYKESISSMDSASKALMVSQRELEKYKSLNKKLIDELDELKFKNGVCSENFENGLRSTEESSNNVKNSNSIRENQFNIKINDLKAELFITNQERDDLKSEVLELKKRLLNLENNTKQVNEDADSDLL
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase.
Subcellular Localization:
Endomembrane system. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Domain:
The RING-type zinc finger domain is responsible for E3 ligase activity.
Sequence:
MGDETQTPQNVMNLDLNLGPVETDPVGGLNLENWLDGPAAGDSFGPRPMARRRRWRSIWRPVAGEGSVAAADQRPPPPPSPPELTKTCDNGDEENELVDGNGDGVTNNESEGGFFDCNICLDMASDPVVTYCGHLFCWPCLYRWLHIHSDVKECPICKGEMTMKTVTPIYGRGNPTRVVEEDSSLKIPNRPQAKRVESFRQTIQRNVFTMPMEEMIRRLGSRFDLTRDLFQGHSFLSENSSLLNRYLASRRLRTDQDQDHNQNQNQNPTLVETFHGRQEPAPSMEDRDSVSSIAAVIQSESQTVDTAVEIDSRVSLSTSSSRRRSESSRVSDVDSGDSRATRRRRLF
The following text describes a protein:
Function:
Involved in the biogenesis of the 60S ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPIYDFRTIGSIPSGKDLVDIVLSKTQRKTPTVIRKTMKICRIRAFYMLKVKFTQNTIGQKISAIVDEFPKIDEIHPFYRYWFNIMYDKDHFKIALGQLHQCKNLTDKVGQHYVKLLKHADSLFQCKTLKRAALGRMISLLRKQNEYLAYLEQVRQHMSRLPSIDPSTRTLLLTGYPSVGKSSFLNALTRANVEVESWDFTTQSLFVGHSDYKGLSYQLIDTPGLLDHPLEERNNIELQAVAALAYLNAAILFLIDISCGGDYLQKQVHLFQSMKLFFQNKPTVIVLSKADTWTPDQLSADDIQLLQSMSPAVSFLEALKLYDVLYPSKAEIDDCLARGGELSLNIQGRVKEEDELRQRILAQAASGDPLFIPASTVNMQGVERAMAIACEQLLRIREAQLFTARKQELLADRQYVANPVQRDSKQRGTYIPESVKALQEAHMPVRAHTIEDGFISERVLELENGGARVYKPDERKNWLLSNDDWKYDAIPYFYKGKNILDFITVDEDIDEKLRLLEEEEERLVAAESAFDDKGLFEKLALYRELTDNRRIKKATLKGMDLLGSSMPRLAQIHGTAAGAKLDRFVMKKTGQKFNSSVARTVFPNPNRPMKDKWRTLQERMEEQARRDGVSVEQMRKIDYQDRHYTGKGRFDYKKPAVTRQKHLLSGKISGQARDRR
The following text describes a protein:
Function:
Escort protein required for cholesterol as well as lipid homeostasis. Regulates export of the SCAP-SREBP complex from the endoplasmic reticulum to the Golgi upon low cholesterol, thereby regulating the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. At high sterol concentrations, formation of a ternary complex with INSIG (INSIG1 or INSIG2) leads to mask the ER export signal in SCAP, promoting retention of the complex in the endoplasmic reticulum. Low sterol concentrations trigger release of INSIG, a conformational change in the SSD domain of SCAP, unmasking of the ER export signal, promoting recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi: in the Golgi, SREBPs are then processed, releasing the transcription factor fragment of SREBPs from the membrane, its import into the nucleus and up-regulation of LDLR, INSIG1 and the mevalonate pathway. Binds cholesterol via its SSD domain.
Subcellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MHFKEEFSIIELVPLLATYLILFLYISFSVSKIEFVKSKWGLALAAVMTVIASLLMSIGLCTLFGLTPTLNGGEIFPYLVVIVGLENILVLTKSVVSTPVHLDVNIRIAQGLSKEGWSITKNLLTELAIACAGYFTFVPAIQEFCMFALVGLLSDFSLQMWFFATVLSIDIRRIELSDLQRQSDRQQGHKTDTATIQSETLTNQTLPRPPPTRLPRSKSAPGLHHLVSQQPRLVTPERPPASVESGEHPNQGLLRAQKRLKFVFFWARTRIVQRFIMLCTVVWIALIVYNTGLVDQLTNATTSRQPLMSPSDNKDSLRSLQDGLQTQADSLRKNHDLDLERKSDTFWNFDGETEGREQKEPWQDLSFRHWPKLFGCYNITLAGRYISILPPILLSLVVPPEEAMAMRHHSEQQEHAQKLQYFMESQVSSHIHDDMTFDPLLAMNKTVRLPFFSSKREYYLTIGLAVLSGAFLVVILMVLYKCVCPRDYGRWAPEGRRLKVVDDPYYIRQISDSVPLVLRGHTQDVECMCSDGPTLVSSCLLGDIRVWDANSGDCLTHISRRITPSSTRQPCYGGNEQYDAWSPQQSPPDLQYHHLTHRGRCQRSLSDSQDQRPKRRKSDLFTNLPNLTGSIDTNFVQLEKERKRETLNGFHHVQGSQPPSPPQPPPATESRPQQVETKSSPQDIPSSSPGYDFRSRFDTYYHEHASLYRRTSKGCSSPDMLVPPSPEQMLNASSSSERSLLSSGSAAELRRMSSTGELSRHDSLAGLYDSVFGESYGTEEEGVATPIWCLGCHDNLVVAGCSNGRIEVWDGLTGSLKCYYHEFAEGVTALCFVNNRIVASRLDGSLDFLIMEARGVVSASPPSMVPAGPVRGHRRNQSYDSFIATSSDTVCCVRLAQRVPHAHQQPINVLQCSAGRVVTGSQDHTLKVYRLEDALCLYTLHGHTNGVTALHLDKTPPLAAASGSLDGDVRLWDMLTGSCVHHLTGHEAGILSLTCTATHVLSSGQDDRICVWDRSRGALLYSIQQDVGCSSTIGVLNSSLLVSGGQGCLYLWNILRGEHLRTVLLGDNDQSQFVRQVQVIYASSVICNYGNQLQVVHFPSVLEKAE
The following text describes a protein:
Function:
Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking, together with YSC84.
Subcellular Localization:
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Localizes independently of F-actin.
Sequence:
MGFLSDHPHTAITETIFRIVSSRDYTLEVELAPLIQLIKADHNDYNYTVNQEEAARALRKKIKYGNRLQQSRTLDLLDLFISQGVKFTVMYNDDKLLQRLRGMATNSENSGSGEKYEPRIIKKCAAYAISWLNYITQNNLENARAYSGLYQLGQTVKQRYSKSSRSRRSGGGSGGRSNFMDDSADDTLYQSNSLTSADRLYRIPQINMNKEAPRIRLIISDALASAVSLQNSLIGLPKGKFSTDDEEATSKFIQARAIRRKVLRYLQLVTEGEFLGSLIHANDELVAALTAYDDRSAQDDSSDESDHGSYDDGIYDENEQDNSRYIDSESSEEESLSSYQPSTISNPFGDHNKI
The following text describes a protein:
Function:
N-acetylglucosamine-induced protein which plays a role in the N-acetylglucosamine metabolic pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MNPATIITNFNNSQLQTPPTSPVSFDKYYTYYNIQLEQSTLMPQPSKIKNGDPFTWSDIQFIIKSNQLEIFARSRQQTIKYHKFKQWLKDNKLSINDYLLDYELHWKESELREQQHELVSDKEYSIDYPEDLIFHNPNDISILYNKFPYYFEPNVKHICIWSKLKIPVDKNSEVGDISVMTKKLINRYLEKTFVAKGISWDQIVWFKNWLSLQSVRSISHIHVILKDVDDKFVDELISGGSGEVLTLDDYRNLE
The following text describes a protein:
Function:
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes.
Subcellular Localization:
Nucleus.
Sequence:
MDLEPAVMGGRRAQEELESLPNKDAFPMVEEMEQEPAVMGPRTKVVRRRRGAMSARPGQRRCRHCGTTKTPQWHRGPAGCRTLCNACGVRYKRERPEHAPSDQGLEVGGGEALGTVEPEPPELGSQTKRVVRQRRTLAWPPTPTAAEPEQQWCQHCGKMKKPQWREGAAAEEEREWLPNKNVPAVETMEPKPSVVAPRTEGAARRAVASPALSDLGQRLCRHCGTAETPQWRQGPEGRKTLCNACGMRYRAGRLVPEYRPLRSPTFSPELHSNRHSRVAQMRPAGAPHPLPPDK
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
Sequence:
MSSPAPNTPSPPSHTSGLPSSLLILERPELSHLAQWSVSSHKYGFGVDNLRDGNDSTFWQSEGAQPHTIDLAFPRKVMISAIAVHMSHPRDDSYTPSKIGIRCGTGVHDLQEVRYMEFSKPDGWHLIPLRPMEHTASRMEKEGPPIPCHFLRVLIFANHLNGKDTHVRGLKVFGPPGPKENTQVSSPSITMSQQAVDEIGSGRRLLELGHDGLSGFTSTEFKMHEWIR
The following text describes a protein:
Function:
Plays a role in the inhibition of host innate immune system by targeting the CGAS enzymatic activity which is the principal cytosolic DNA sensor that detects invading viral DNA. Acts by inhibiting CGAS-DNA phase separation: directly binds double-stranded DNA (dsDNA) in a length dependent but sequence independent manner and is able to form DNA-induced phase separation in infected cells. DNA phase separation of ORF52 mediates disruption of liquid-like droplets in which CGAS is activated, thereby preventing CGAS activity (By similarity).
Subcellular Localization:
Virion tegument. Host cytoplasm.
Sequence:
MSAPRKVRLPSVKAVDMSMEDMAARLARLESENKALKQQVLRGGACASSTSVPSAPVPPPEPLTARQREVMITQATGRLASQAMKKIEDKVRKSVDGVTTRNEMENILQNLTLRIQVSMLGAKGQPSPGEGTRPRESNDPNATRRARSRSRGREAKKVQISD
The following text describes a protein:
Function:
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
Sequence:
MSQTPPAEPTLRLFIALELPQPVRDELKRIQQRLQGHSRAARWTDPTGMHLTLHFLGETPERLVEPLLTGLRSVSAPALSLTLDRLGCFPANGALRVVWVGLRGDLAALATLHRSLATVIQSLGLPTETRPFVPHITLARARPNATAADLRALRTALDTVAPQSLTWQSDSPRLFRSQLTPRGAVYTVLG
The following text describes a protein:
Function:
May act as a negative regulator of salt tolerance.
Subcellular Localization:
Cytoplasm.
Sequence:
MNDKALRTEALSVGLEPPSFKDLLIPIPNSGTKKKNKKKKKPKAKKNVETQANVDLLGSAGTDSAVTDVGANNGVIDHQASLELSNLNSRISHPQLVSANGDDSSLINVEGISSTDWQFTLESDDTIEHSPQCILSTSSFVDEAEFPVHIPGLEDATSSNMSPNSVQNNMNLNTVALGSSTSSKRKKKKKKKSKANSASLNVDDQRDFEQVYSTDVAITYRNGQALSYYNGSVRQASMNNNVNNNKSKDIWSSSNTEEREQIREFWLSLSESERRSLVKVEKEAVLQKMKEQQKYSCSCSVCGRKRLAIEEELEVLYDAYYEELEQYANIQRNLANTESVNASDEGSDKSQKGIISDSPKLLSIPLNNVPSKSLNDDITQDELNSSNADVDEEVIETTSLEEKNVDNQEFVTSISNGNQTLEDTSHSPQTQPPFQPPYPSKADEKNSYHSDLYNFGSSLTVKGGILTVADDLLKNDGKKFIEMMEQLAERRMQREDNSNFHEPELYESGLEYDEDEEEDEEDVDEDELDLMTDEQRMEEGRRMFQIFAARLFEQRVLQAYREKVAQQRQAKLLEEIEEENKRKQERELKKIREKEKKRDKKKQLKLAKEEERQRREAERLAEQAAQKALEAKRQEEARKKREEQRLKREQEKKQQELERQKREEKQKQKEREKKLKKQQQEADREKMAREQRLREEEEKRILEERKRREKLDKEEEERRRRELLEKESEEKERRLREAKIAAFFAPNQTKEGSDGCTTSSQLGLFEKKGDLVNDEDKLSSHLLDSVPNALRQAPIGLKNTNNLSERNASSNLLNSSLFSSFNSVNPLISLEPNPLNRTLNNSVNLTDFGRKPNGLHSPSSLLSNSNNFGLNPNARHSLSRANSPVHHYPFATPPSQRANKYPLNNGANVPALLNSFSSPQLSPLVNRVLNEPSSSPLSSSSLKSPLSKEGVLNQQGHEQYNFSLSPSIRNKLSPICRPSQGSSPKLKNNLSNTEERMGSRALLDDKTDSVITASNSTTSGLSRDESSNPNNYELLNAFNQNTWKISRSTSNKSLIPESPWGVALGAFTPNASTQSIPWGNRTWTD
The following text describes a protein:
Function:
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Sequence:
MSWSDKRRHWRARKSQVNWYLWSGIGFLSLVIGSFVFGGYLLHKFLNDASTLPIEAVAIKGERTYTTDKDIQIALQDLMQRSFFSADITLVQQALEALPWVYRASVRREWPAKLRVYLQEQQPAAHWNGTAWLNVHGEVFEAPSHPELEHLPHLSGPDDMGTEVLTAYAQVNSLLKINGFTLASLNLTPRHAWHATLGNGIVLDLGREDKMARIQRFITVYPLLAKQDKPIARVDLRYDTGLAVGWGDAQTREPIINDEKPR
The following text describes a protein:
Function:
Component of the signaling pathway of IL-1 and Toll-like receptors (By similarity). Inhibits cell activation by microbial products (By similarity). Recruits IRAK1 to the IL-1 receptor complex (By similarity). Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates (By similarity). The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity). In a complex with TOM1, recruits ubiquitin-conjugated proteins onto early endosomes (By similarity). Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P) (By similarity).
Subcellular Localization:
Cytoplasm. Endosome. Early endosome. Note=Localized to endo/exosomal vesicles.
Domain:
Both ATG8-interaction motifs (AIM1 and AIM2) are required for the association with ATG8 family proteins; The N-terminal TOM1-binding domain (residues 1-53) is a disordered domain that partially folds when bound to the GAT domain of TOM1.
Sequence:
MATTVSTQRGPVYIGELPQDFLRITPTQQQQQIQLDAQAAQQLQYGGALGTVGRLSVTVVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHVTIPEALKQGKVVDEWYSLSGRQGDDKEGMINLVLSYTSLPAAMMMPPQPVVLMPTVYQQGVGYVPITGMPTVCSPGVVPVALPPAVSAQPRCSEEDLKAIQDMFPNMDREVIRSVLEAQRGSRDAAINSLLQMGEES
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSNLYATEPATNGKVIIDTTAGEIEVELWGKECPKAVRNFLALTMEGYYDGVIFHRVVPGFIIQSGDPTGTGMGGESFYGEPFEDEIHGRLKFNRRGLLGMANNGSRNSNTSQFFITLDAAPELTNKHTMFGKIVGNTIFNVLNIGNLDTDKEERPLIPPKIRRIHIIENPFDDIVPRITAEEKKAQQKAKLEAKKDMEQRERRAKAKKNTGLLSFGDSEEIPEEEVTVKKKSMTRQDLVDPSEAEHTKSKTSKMTETFVNIPPSLKDLGKSRENEASEEKKAVDLKNIRAQHEREKAGGSAARQAEIKRMEEDLRRLKKRSGSVSDSESDSSSRARRKGPSYLEQELAKYASKRGRAAMKAGNKRGRRDEEEDVLTEMRKFSKRVMQAGDEPEEEQAEEIEEGEAKEEGTGIGAAMAEEEGGIEVDDDVGWLTHKLKFQVDDKELTRRAEDEYAVIDPRAKARDLLGKPDKKKLKGNPNRRTVRNSGRNR
The following text describes a protein:
Function:
Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit; Required for proper chromosome segregation during mitosis and error-free mitotic progression.
Subcellular Localization:
Chromosome. Nucleus, nucleolus.
Sequence:
MASSKNDVKNVKIPRGKPKSGRVWKSEKKKKSTVINVKPLHSSWKKKQKDRLQLKLLKSYEKELKDNARNAKEERRKRTMEKQKRREENERKSQVVQVIKNTSKIKKMKKKQLRYIENR
The following text describes a protein:
Function:
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
Miscellaneous:
MISCELLANEOUS: In plastids the F-type ATPase is also known as CF(1)CF(0).
Subcellular Localization:
Membrane; Single-pass membrane protein. Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MINLSILISSSEVSGPGGLFDINATLPLVAIQFILLMVTLNIILYSPLLTIIEERKEYVLSHLAQASEKLAQAKELTTQYEQDLETARKEAQLEIANSQNIHKEILDIELDISQKYIDNLLETISSDLLNKKKTALDSLDTIVTSLCTEVETKLSI
The following text describes a protein:
Function:
Participates in maintaining the H3K27me3 mark at target genes by interacting with LHP1-PRC2 complexes during replication, thus contributing to H3K27me3 inheritance.
Subcellular Localization:
Nucleus.
Sequence:
MKSRSLKLREAHKVGGSAAFCSILWDHKAEHFVTSSSSDPSISVHDGLSTSTLPPTILRHHQDGVTSLALSNDSTLLASGSIDHCVKLYKFPSGEFQTNITRFTLPIRVLAFNGSGSLLAAAGDDEGIKLINTFDGSIVRVLKGHKGPVTGLDFHPNGELLASIDTTGTVLCWELQNGVVSFTLKGVAPDTGFNTSIVNIPRWSPDGRTLAVPGLRNDVVMYDRFTGEKLFALRGDHLEAICYLTWAPNGKYIATSGLDKQVLLWDVDKKQDIDRHKFEERICCMSWKPNGNALSVIDAKGRYGVWESLVPSSMLSPTVGVPDIVPKKRNEILDFDDEVEEEIYRASESLDDAMGDSDDGESHHTSRKRLRKKTLIDEDVDDAYEELNDGSSLPSASEYRKKSHRGHREKQGARSGAFKGISASTKYKMQSSFQPGATPPEPGKRTFLCYNMLGCITTIEHEGNSRIETDFHDTGRGPRVSSMIDIYGFTMASINETGCVFANPCKGEKNMSVLMYRPFRSWASNSEWTMRFEGEEVKVVANGSGWVAAVTSLNLLRVFSEGGLQKHILSLDGPVVTAVGCKDHLAVVTHVSDCLPSNEQVMEFRVFNISKMTQELKGRVALTPGSRLTWIGFSEEGSLSSYDSEGVLRVFTSQYGGSWIPVFSTSKEKKQEENYWVVGLNTSSLYCIACKYAEMFPQVTPKPILTILDLSLPLASSDLGAASLENELILKQLRLYETQRKVDDMALVGVDTTALEDEAFDLEVSQDKCILRLISSCCSSDSFARASELMELLTLEKSMRAAITLVTKLKLPFLAEKFSSILEERLLEEASEAAVTNPALNPNGEVVTRVESKVQNPPASIQTSENTEAVMKSSATKLSAPTLLKKSKVSEGLKLGKEQTKKDKSDDAKIKEIKKLNLKNPVNNVNKEDKGQEKEVNQGEARRSSNPFLKSTV
The following text describes a protein:
Function:
Transcription factor involved in stress responses (Probable). Positive regulator of the jasmonic acid (JA)- mediated signaling pathway. Triggers the up-regulation of LOX3, VSP2, PAL1 and PAL2 in a JA-dependent manner. Promotes drought and osmotic stress tolerance by preventing reactive oxygen species (ROS) production (e.g. H(2)O(2)).
Subcellular Localization:
Nucleus.
Domain:
Contains a slightly degenerated ERF-associated amphiphilic repression (EAR) motif, which may be involved in the activity of transcriptional repression.
Sequence:
MKRDRSDYEESMKHIDIVESLMMLSRSFVVKQIDVKQSTGSKTNHNNHFECKTCNRKFDSFQALGGHRASHKKPKLIVDQEQVKHRNKENDMHKCTICDQMFGTGQALGGHMRKHRTSMITEQSIVPSVVYSRPVFNRCSSSKEILDLNLTPLENDLVLIFGKNLVPQIDLKFVN
The following text describes a protein:
Function:
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MLAAAIVATTLSFVEPKFNHVWLFLFVVPVVRGVTMKKSRNLNMEKFQALGRNGLVFLALAVICWVLDRVFCPFMLSIRFPYLHAVWHILVLIAANMVFVFGAFDYANQTASRHEPYLAFVPLLGSYVGIWYVAFRLPNRKST
The following text describes a protein:
Function:
Required for arbuscular mycorrhiza (AM) development during AM symbiosis with AM fungi (e.g. Glomeromycota intraradices).
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MNINKMELTPILLLGFILLLSICQTSANKYQKLAAANEGLEDQSSLLTYIVHVEKPSLQSKESLDGWYNSLLPAATIKTQNQQRVIFSYQNVMNGFAVKLTPEEAKALEEKEEVLSIRPENILSLHTTHTPSFLGLQQSQGLWINSNLGKGIIIGILDTGISLSHPSFSDEGMPSPPAKWNGHCEFTGERICNKKLIGARNFVTDTNLSLPFDDVGHGTHTASTAAGRLVQGANVFGNAKGTATGMAPDAHLAIYKVCSSSGCPESATLAGMDAAVEDGVDVLSISLNGPTNPFFEDVIALGAFSANQKGIFVSCSAGNFGPDYGTTSNEAPWILTVGASTTDRKIEAIAKLGNGEKYIGESVFQPKEFASTLLPLVYAGSVNISDNSIAFCGPISMKNIDVKGKVVLCEEGGLVSQAAKAQAVKDAGGSAMILMNSKLQGFDPKSDVQDNLPAALVSYSAGLSIKDYINSTSTPMATILFNGTVIGNPNAPQVAYFSSRGPNQESPGILKPDIIGPGVNILAAWHVSLDNNIPPYNIISGTSMSCPHLSGIAALLKNSHPDWSPAAIKSAIMTTAYEVNLQGKAILDQRLKPADLFATGAGHVNPSKANDPGLVYDIEPNDYVPYLCGLNYTDRHVGIILQQKVKCSDIKSIPQAQLNYPSFSILLGSTSQFYTRTVTNVGPINMTYNVEIDVPLAVDISIKPAQITFTEKKQKVTYSVAFTPENIVNRGDKEISQGSIKWVSGKYTVRIPISVIFV
The following text describes a protein:
Function:
Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III (Pol III) which synthesizes small non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs from at least 500 distinct genomic loci. With POLR3H/RPC8 forms a mobile stalk that protrudes from Pol III core and functions primarily in transcription initiation. Pol III plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-kappa-B through the RIG-I pathway.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus.
Sequence:
MNTVQINSALLCDSEVLNFLQESTKRRSKKQNTATFQDLHTVEYEVVTYLSALPCKDQTKPQVNSFLEAIKTWSLTKAEKLQLLNLRPVSAIELSAIIEECEIRFTEDQLTELLQILNDTLPYDKPVLDNIQE
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MYTAFPCSSLFSVARRHCNPFNVVSSRSFATTTRVDCSTHLASSFPATTRQSHSASSSTCTSSSKMQPVAQLVSKNKAWSADFLAKKPELAAHLAQRQTPKMLWFGCADSRVPETTICDAEPGDFFVSRNIANQFRLDDTAANALLTFAVQSVGIEHVCVVGHSSCGGVLAAIGGATTPPSEKDIESSALLQHLIPLFKLAKEVCEANPGLSNDELAFKVVSASVKQQIDNIISTSIIQDNWNGVTSPLSGKVMNKVQVHGLFYDIGKQELIDLDLSRSAP
The following text describes a protein:
Function:
GTP-binding protein which is required for the light-dependent internalization of the TRPL ion channel from the rhabdomere on the apical surface of photoreceptor cells to the cell body and for the recycling of TRPL back to the rhabdomere in the dark. Binds to 3-phosphoinositide (PtdIns(3)P) and phosphatic acid and so may interact with membranes, particularly the early endosome membrane where PtdIns(3)P is predominantly localized. Plays a role in preventing photoreceptor degeneration.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MATLLSNGQQSVMASTSNGQEQQRHQDEPEQQQQVEIRKSSSPKPGAMPSLKLNRMGSVSPKDKRVYKIVLTGGPCGGKTTGQSRLCTFFENLGWKVFRVPETATVLLSGGVKFSDLTEKEAYKFQENLIRTMVQIENTYFELGNSSNRNCLIICDRGVMDASAYISKDKWEKMMAGNNWNPVEMRDNRYNQILHLVSAANGAEDFYSTEDHACRSEGVDLARELDYKSAAAWVGHPYFDVIDNSTNFETKMNRMIESVCQKLGIDIGDRLQATSRKLKYLVALLPPDSEFPPFQDFDVVHHYLQSAGPKVQARLRKRGQKNHWSYIHTQRRPNVHGQARIEVKTQLTHRDYMNLLAQRDDAHFTIYKKRRCFLINNQYFQLDIYKEPGHPRCKGLVLLETYSSLTGDALKNCMPKFLNIVKEVTGDPDYSMFNLSLKEDWSTTKKFCRSATHGKQEEQSPVPAKQYHPYDENSD