lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKEQKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDGYLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFRNRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVNSPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRLREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLFRVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNSILMFRHSQELPEEDIASGQEVRG
The following text describes a protein:
Function:
Required for the formation of the blade-sheath boundary in leaves. Promotes flowering.
Subcellular Localization:
Nucleus.
Sequence:
MVQGEESSWRMERAALPLNQALAYGVQAHAAAAAAPPTCFLDFQPAAASAAYFGFGELEEALIHGGGAASAGGGVDPGVIIKNDVAQAKSAAGYLAGAGTGRPPTLEIFPSWPMRHQQQLHSGNSQSVGSTGTDSSSAQNTMSQMELVSPASSAPRQEVMMVTTDDYSYKPGLAAAPAAAAPPSFQQHHPLPLQLHGGEGGGDHDKRKHGSTRKDGKLVDAKTERRLAQNREAARKSRLRKKAYVQQLETSRIRLQQVEHELQRARSQGLFVGGCSAAGDMSSGAAMFDMEYARWLDDDTKRLAELRGGLQAHLLDGNLGLIVEECMQHYDELFQLKAALARSDVFHLLTGSWATPAERCFFWMGGFRPSELLKILIPQLDPLTEQQLLGICNLQQSSEQAEEALAQGLHQLHQSLADTVAAGTLNDGAAAPNYMNIMAVALEKLASLENFYQQADNLRHQTLHQMRRILTTRQAARCFLSIGEYYSRLRALSNLWASRPRDNFIGTESLSPTATELQALHHQQQNQFAGF
The following text describes a protein:
Function:
Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity (By similarity). Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface (By similarity). Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell membrane, sarcolemma, T-tubule; Multi-pass membrane protein. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, cytoskeleton.
Sequence:
MGHVLSFTHCKDAPSTASSTPDSCPPEGEEDDSPVTEVNFWPLPSPHEPTFSYITIGSTAPLSRPPVRARRGLGQSRVHAAPREETEEKEVKDVVTYVLLEKTCQLKKLSPPHVQEEVVFVAKPQPQLEVFRAVKDLLYWRDILLSAGCLTGVTLSLLCLSQFSVISVFAYGCLIILSVTLTLRLYTKLLHALKRGNGANPFQYYLDADLKLTTKQAEEITARVLSLLSTTICTLRSLFLVEELKDSLKFLVIIYLLTYVGAVFNGITVLLLCVIGAFTFPILYKQHQTQVDHYVSLVSKKGNAFRSKIQGTVKKPPAKQK
The following text describes a protein:
Function:
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Subcellular Localization:
Mitochondrion.
Sequence:
MSWGQGAKRPILGLLFRAQQQSCRGHRYSSSTFQAHQLGTHVPQDGVFLRRFSSEVPASEQMNLIRQLRQRTSAPIKDVKASLVSCNWDIEAAHKDLRKRGVALAAKKSSRTAAEGLLAIAQDEKRAAVASSLAKMVLSAQGPGELFLPFGPEYMENMSINLDHPKLNGETTVQSAVTEVDAMVGENVKLRRGFMLSTTGHGVVSSYMHTCPPPGLGRIAGLVTLEAEDSSSLLDALKRVPLENERDILRTQAESSGKSQMAMDKMVEGRLRKYFEEVVLMEQKYILNDSINIKTVLNDLSKEVGSKVTIGKFIRMQVGEGIERYNIIVPHVISADKCFFFLD
The following text describes a protein:
Function:
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MKSALFSRFFILLPWILIVIIMLDVDTRRPAPPLTPRPYFSPYAVGRGGARLPPRRGGPDSGPGRGWEKRNESRPHARPRPEPPLPTIYAITPTYSRPVQKAELTRLANTFRQVAQLHWILVEDAAARSELVSRFLARAGLPSTHLHVPTPRRYKRPGLPRATEQRNAGLAWLRQRHQHQRAQPGVLFFADDDNTYSLELFQEMRTTRKVSVWPVGLVGGRRYERPLVENGKVVGWYTGWRADRPFAIDMAGFAVSLQVILSNPKAVFKRRGSQPGMQESDFLKQITTVEELEPKANNCTKVLVWHTRTEKVNLANEPKYRLDTVKIEV
The following text describes a protein:
Function:
Positively regulates the expression of PE13 and PPE18. Can also regulate expression of some other genes. Plays a role in modulation of innate immune responses.
Sequence:
MYSTNRTSQSLSRKPGRKHQLRSHRYVMPPSLHLSDSAAASVFRAVRLRGPVGRDVIAGSTSLSIATVNRQVIALLEAGLLRERADLAVSGAIGRPRVPVEVNHEPFVTLGIHIGARTTSIVATDLFGRTLDTVETPTPRNAAGAALTSLADSADRYLQRWRRRRALWVGVTLGGAVDSATGHVDHPRLGWRQAPVGPVLADALGLPVSVASHVDAMAGAELMLGMRRFAPSSSTSLYVYARETVGYALMIGGRVHCPASGPGTIAPLPVHSEMLGGTGQLESTVSDEAVLAAARRLRIIPGIASRTRTGGSATAITDLLRVARAGNQQAKELLAERARVLGGAVALLRDLLNPDEVVVGGQAFTEYPEAMEQVEAAFTAGSVLAPRDIRVTVFGNRVQEAGAGIVSLSGLYADPLGALRRSGALDARLQDTAPEALA
The following text describes a protein:
Function:
May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Secreted.
Domain:
The N-terminal domain is sufficient to interact with BMP4.
Sequence:
MKLHYVAVLTLAILMFLTWLPESLSCNKALCASDVSKCLIQELCQCRPGEGNCSCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELSHHENLVSFLETVNQPHHQNVSVPSNNVHAPYSSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF
The following text describes a protein:
Function:
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
Subcellular Localization:
Cytoplasm. Endosome.
Sequence:
MSSWESCEDGNLVRTGEIVLFVQNETRYHEGDGNLNYDEGKLTLSTDNIFFQPKGAGPIFLRIPLGNIDSPSGGPTVVAQSDGRSPKLHIPLTESGQKAVFSFKVGNIKEFCETLRDVLQQKLLLLRHSEMLTEPLPSITGVVQGSSKATRDDSSAAPANETLLAFTDKAGIAGLMRASAEKTAQGETLRDIDDVMRNASSLVASIRNLQQKQQNIAGTTKAEDNMTIESIEATLGLGATVRASGAGWGLVSAHAGFHKELAWEIHSWITHEKNHHVFGSMPLIPLIELFSLYNKARGECDLVSTNDVLHACRALDQQEYAQYTLKRLSSGRYALQRKDPSIVLKKLEHILGPRLCNEKESGKFTTSADSSPIHNGRDGGVTQPVTQTAVFPESSSMLKGVNEVTFASVLHVTCSVSMDLLEELELQGYLCRSGGEFGCFTFHWNIFVF
The following text describes a protein:
Function:
Co-chaperone for hsp90/daf-21. Involved in regulation of longevity, larval entry and exit from the dauer stage of development and response to environmental cues, such as oxidative stress, in a temperature-dependent manner. Role in daf-16 and hsf-1 inhibition at elevated temperatures.
Sequence:
MAKQPTVLWAQRESLVYLTIEVDEAKIEELKGEGNKLHFQGSSKTDKYEATLEFFDEIDPASVKHTGSSTRVVEITVQKKTPAWWPRLLQNKGKVHWLKVDFGKWKDEDEDDEAEDAGAGIGGGMANGFDLNQYMSQMGGAGGADFGGLEDDEEDDDMPDLEDNEEEEGKNGTRA
The following text describes a protein:
Function:
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
Subcellular Localization:
Nucleus.
Sequence:
MESFLDYIGQNGFGNQKPDFVTSKDVLQTATCSEKQINPRMQKSQMESFLDYIGQNGFGNQKPDFVTSKDLLKSVTSLETHLIHVCKVGGVIFVLKMDKENAMESKNQLIFNHLMTKKSENEPIRNDSIQKGVWKAEMLNGGKKEYSILYSGKVDAIQKTKMGKSRNYELEVAFGGCENDAFWWEKSCKLFWKSFFGASPSIIIASRTGEFALKKKINDIMITYPKNSIYEIKELSRDELPSLAAPNNQRPLWTVSDGKKNLYNFLKLVKSHVKRDGDCFVISRIPGSQKWNFKQDIASVGTFKEAIQISIPNL
The following text describes a protein:
Function:
Involved in translational control mechanisms operating in early stages of oogenesis. Required maternally in many stages of oogenesis, including cystocyte differentiation, oocyte differentiation, and specification of anterior-posterior polarity in the developing cysts. Essential for the formation and/or structural integrity of perinuclear nuage particles during germ cell formation. Required for gus, Fsn and aub accumulation at the posterior pole of the embryo. Required for the localization of vas to the perinuclear region of nurse cells. May have a role in production of piwi-interacting RNA (piRNA).
Subcellular Localization:
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Note=Component of the perinuclear meiotic nuage (also known as germline granule or P granule), a germline-specific membraneless ribonucleoprotein biocondensate involved in post-transcriptional regulation of transposons and mRNAs. Localization to the nuage is dependent on spn-E. During late stages of oogenesis seen in the pole plasm at the posterior end of the oocyte.
Domain:
The B30.2/SPRY domain-binding motif mediates recognition by proteins containing a B30.2/SPRY domain.
Sequence:
MSDDWDDEPIVDTRGARGGDWSDDEDTAKSFSGEAEGDGVGGSGGEGGGYQGGNRDVFGRIGGGRGGGAGGYRGGNRDGGGFHGGRREGERDFRGGEGGFRGGQGGSRGGQGGSRGGQGGFRGGEGGFRGRLYENEDGDERRGRLDREERGGERRGRLDREERGGERGERGDGGFARRRRNEDDINNNNNIVEDVERKREFYIPPEPSNDAIEIFSSGIASGIHFSKYNNIPVKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVNKYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAADLVKILEGSGQTVPDFLRTCGAGGDGGYSNQNFGGVDVRGRGNYVGDATNVEEEEQWD
The following text describes a protein:
Function:
Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
Sequence:
MRLIGRLRLLMVGLVVICGACACDRVSAGRWSESPSATSWPVRPVNTTTPSGPVPPVSEAARAAGLVDVRGVVPDAAIDLRYATANNFTGTQLYPPGARCLVHESMAEGLAAAAAVLRPHGQVLVFWDCYRPHDVQVRMFDVVPNPAWVARPGKYAHSHEAGRSVDVTFASAQRQCPSVRRSGELCLADMGTDFDDFSSRATAFATQGVSAEAQANRAHLRAAMQAGGLTVYSGEWWHFDGPGAGVDRPILEVPVD
The following text describes a protein:
Function:
Involved in a novel pathway of export of proteins that lack a cleavable signal sequence. May be part of the export machinery or may also be a substrate for non-classical export (By similarity).
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MSQPYLISKWMDPLFGIFVGTYGYYLYEKEHRPRGRSLRELALRKWNKQAVSQQSMKN
The following text describes a protein:
Function:
Vacuolar Fe(2+) uptake transporter.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
METTNGTSINNHKFTIPAVNDVEQQQASMELEPTDDFNYSKRSQWLRAAVLGANDGLVSTAALMMGVGAVKQDIKAMILTGFAGLVAGACSMAIGEFVSVYSQLDIEVAQLKRDKLRDENRETTDEEEEQEGSKGEKESLPNPLQASAASALSFSVGAMVPLLAASFIKEYKVRLGVVVGAVSLALAVFGWLGAVLGRAPRVRSAVRVLVGGWLAMAITFGLTKLIGSSGL
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MFHKYQKSRSQVKEEKQKERKAFDDEVDSINERLNQIAHNNYIDPGMTDEFSSLPILESTKKSLEKSKFTKMSPIQKQTLLYTLCGRDIIGAAETGSGKTLAFCIPIVESLKKAKFSKMSGIGAIIISPTRDLAAQTFDVLKKLIKDTDISAGLITGGMDFEMEQEGLSRLNIIICTMGRLKEHMETTSTFNADHLQILVLDEADKLMNKEFIRDLKHVIADLPDTRQTMLFTATATKAIKDISKLSLSNPARVNLTEERSTVMPESLIQFYAIVNLSEKWNTLFSFLKMHLNDKIIVFMETVKMVRFAYEAFKHLRPGLPILHLTGKQNSNLRFDVIREFKSQKRCAIFTTDVAARGLDFPDITWVVQMDCPSSTDTYIHRAGRTARFHKMGKSIVFLTPSEKMMVEKLAKLNIELKGAQIIGDNLVDIRPRLVDICARFSDVKHLAMKAVTTYIRSVKHHEDGEVFVVQNILDELEDFSKSFGLLSVPVRKQTKKVIEEKSDNENESSDDGEEDDEEEKSDDFFEVVDDEDDKESKEIAESSGPKPTTMEFRSPDEPIPQEEYEAWRNRLKNLLSGEKKPKSEKKTKEQHRKEREEKRMAKEEREEEEEEEEKKEKTLEEAAAEALLDDLD
The following text describes a protein:
Function:
Catalyzes the transfer of a sulfate group to position 3 of non-reducing beta-galactosyl residues in glycerolipids and sphingolipids, therefore participates in the biosynthesis of sulfoglycolipids. Catalyzes the synthesis of galactosylceramide sulfate (sulfatide), a major lipid component of the myelin sheath and of monogalactosylalkylacylglycerol sulfate (seminolipid), present in spermatocytes. Seems to prefer beta-glycosides at the non-reducing termini of sugar chains attached to a lipid moiety. Also acts on lactosylceramide, galactosyl 1-alkyl-2-sn-glycerol and galactosyl diacylglycerol (in vitro).
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MLPPQKKPWESMAKGLVLGALFTSFLLLVYSYAVPPLHAGLASTTPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKFAFPNGRNDFDYPTFFARSLVQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRDPARLFESSFHYFGPVVPLTWKLSAGDKLTEFLQDPDRYYDPNGFNAHYLRNLLFFDLGYDNSLDPSSPQVQEHILEVERRFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNARRDSPVPRLSGELYGRATAWNMLDSHLYRHFNASFWRKVEAFGRERMAREVAALRHANERMRTICIDGGHAVDAAAIQDEAMQPWQPLGTKSILGYNLKKSIGQRHAQLCRRMLTPEIQYLMDLGANLWVTKLWKFIRDFLRW
The following text describes a protein:
Function:
Transcription factor that regulates specifically the 4'-methoxyviridicatin/aspoquinolone biosynthesis cluster.
Subcellular Localization:
Nucleus.
Sequence:
MPKRVLKGAAKRAREAKHARDAAKARRLSSFLNVRLNQEHIPHEILPNSASDDKLLDRPVTGADLFAPSSGPSSNSVYPSLLQEEYFWNYFWQTYHVSLCPILDDAQFKQHYQSLLIADGKGRKPSALVDIVVAACMQYHISTLPLGSQSGLVEGKDASVAGRWHYWRGQTLLTYELESLSISTLQCHVLCSIYLCGGSFHNMMDTAMAQAVRTAYILGLHRDLPSTLPEAKREMRRRLWWTVYFMDTRATMKLGRSFMLSESHSMPALCIDSLRVAASSGSTFVPADEDMTWLSFNLRQITLCRTFRAAYTSFHNTDFHLQEGQPIWDRPDALQAGAEIIAKHIPSLDAWCDSVPDALKLKRQDSNSRPFSTDGARVVLELSAPEWLQRQRMLLENTYHHVCVNLFRSMICFPYQPASQVHISENSLPGELATRCAAHAIALTKLTHQVLEETSLLDGWHEAFYCQWDAVMTLIGFVLAYPGSGTVTLEAKSAIHLAIAVSENFGFKFAVGTSASKIVQGLCAKSETLTANEYASAYIGASTQNANIYRIYGGQICGVIDWQNS
The following text describes a protein:
Function:
Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
Domain:
Atypical domain architecture: contains 12 HAMP domains and two receiver domains.
Sequence:
MELELDELLNQCIHCCPHCKNKISISQLSACNLIKNRFYELNNKYNNFKNNNIYDIDCNNNSNLNNTNNNNNNNNNNDNNNSNNSFRNILNKDKDITNNNSHFNISDSFINFNNKIKNKSNKIKNGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGESYNLFLDSLLKSLETVKGGDFKSRVKSNEQLFTEKENKIISTYNEILNFQDSTVTEFKRIEKQVGKEGNVMSRAFLPNAVGSWEFCIEFVNNLIGDMIQPTEEVIKVITSVARGDLSQTINLELGQGRKLTGEFLRIAKVVNTMVSQLNSFSSEVTRVAREVGTDGKLGGQAVVTGVDGIWKDLTDNVNTMAANLTGQVREIALVTTAVATGDLSKKITLDVKGEIQELKLTINTMVDQLKSFSSEVTRVSREVGTEGILGGQAQVKGVDGVWKDLTDNVNTMAANLTGQVRSIAEVTTAVAEGDLSKNITIDAQGEILQLKNTINTMVQQLKGFSSEVTRVAREVGTKGILGGQAEVTGVGGVWKGLTDNVNTMAANLTGQVRSIAEVTTAVAKGDLSKNITIDAQGEILQLKNTINTMVDQLKSFSSEVTRVSREVGTEGILGGQAEVTGVDGVWKGLTDNVNTMAANLTGQVRSIAEVTTAVAKGDLSKNITIDAQGEILQLKNTINTMVQQLKSFSSEVTRVSREVGTEGILGGQAQVEGVGGVWKDLTDNVNTMAANLTGQVRSIAEVTTAVACGDLSKNITIDAEGEILQLKNTINTMVDQLKSFSSEVTRVAREVGTEGILGGQAQVEGLGVGGVWKDLTDNVNTMAANLTGQVRSIAEVTTAVAEGDLSKQVSINAQGEILQLKNTINTMVDQLKSFSSEVTRVSREVGTEGILGGQAQVKGVGGVWKDLTENVNTMAANLTGQVRSIAEVTTAVACGDLSKNITIDAKGEILQLKNTINTMVQQLKGFSSEVTRVSREVGTEGILGGQAQVEGVGGVWKDLTDNVNTMAANLTGQVRSIAEVTTAVACGDLSKKISIDAQGEICELKNTINTMVDQLKSFSSEVTRVAREVGTEGILGGQAEVKDVGGVWKGLTDNVNTMAANLTGQVRSIAEVTTAVACGDLSKKISIDVRGEFLELKITINTMVDLLNSFSSEVTRVALEVGTEGILGGQAQVEGVDGVWKYLTQNVNTMAANLTSQVREIANVTTAVANGDLSKKVNLDVRGEILQLKITINTMVDQLNSFSSEVTRVAREVGTEGMLGGQAQVEGVGGVWKDLTDNVNTMAANLTTQVRSIAEIAKAVTKGDFTRVISVDAKGEVNLLKLIINEMIHNLKETTLKNTLAKETAEAASRAKSDFMANMSHEIRTPMNGIIGMTDLTLDTELTAEQREYLSMVQSSAGSLLTIINDILDFSKIEAGRLELDQAEFSLRAHLYDALKTLSWRAHQKCIELVCDIASDVPDSLIGDPGRLRQIVNNLVGNAIKFTSQGEVDLVVKVEKSLSCGEVVLKFSVIDTGIGIPKDKLHLIFEAFSQADGSITRRYGGTGLGLTISTRLVELMKGKLSVVSKSGKGSTFEFTAQFPTSPNQLPLTEKLNDVHTLIVDDNKSTLKVLKQILSEFGITSEVSNNTQDAFNMIVKATKTTKPFEFIFVDAQLGTSLIDMMVEKNMNHCKTKIIMLISGGGQRGYPDSSSNFITGYLSKPVSPSEIFDILTRQGITRQIPKQLCKKIQLTSEIFGDILLAEDNAVNQRLAIRLLEKFGHRVQLAENGLQAVASSQLRKFDLILMDVQMPHCGGFEATAQIRKREHEQGIHTPIIAMTAHALARDRVKCLEAGMDDYISKPINPDQLKAMIEKYLFISKSCNSYEQFQQLQAQKSANYINSTSYYGQLTPTTTTTTTTTTALPSPQKILSIEDDKNLNSNDNNEKDNNNQNNNNNQNDNNKNDNNQNDFDQIKTISNNKESGVGENKKTTRNTSDNERIPKKSDMFDGDFVVQPQLVNRSSSNNKKSNDINGKPQQSQQQPHQQEQQQDIYSSKHQQQSNSPPLANTKRKENDLSNSSIPASKKNNTKQ
The following text describes a protein:
Function:
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).
Sequence:
MNSLLLRSAQENDTKDKYQEAFQEADVDCVSLSPIGFEFIDLDTLYAHISHPEDHSGLIFSSPRTVQSVALCLERHDTNDEWNSRLRDEWSKLHAFSVGTSTGGVVRKLGLHPVGEDSGNAENLCKIILEAVKPGSKPLLYPCGTMRRETIPKTLKKEGILFTEDVAYQTVPNPDLEQELAKYMQEKGAPFCIVFFSPSGVQYSKEVFDKFKADLHNTKLLAIGGTTRVAMQEHGYMVAGVAEKPNPTALLQAIQQCQGGTDG
The following text describes a protein:
Function:
Involved in the maturation of the plastid protein translocation channel. Required for the biogenesis of plastid internal membranes. May also function as a thylakoidal processing peptidase.
Subcellular Localization:
Plastid, chloroplast envelope. Plastid, chloroplast thylakoid membrane. Note=May be located at the envelope membranes in premature chloroplast and at the thylakoidal membrane in mature chloroplasts.
Sequence:
MMVMISLHFSTPPLAFLKSDSNSRFLKNPNPNFIQFTPKSQLLFPQRLNFNTGTNLNRRTLSCYGIKDSSETTKSAPSLDSGDGGGGDGGDDDKGEVEEKNRLFPEWLDFTSDDAQTVFVAIAVSLAFRYFIAEPRYIPSLSMYPTFDVGDRLVAEKVSYYFRKPCANDIVIFKSPPVLQEVGYTDADVFIKRIVAKEGDLVEVHNGKLMVNGVARNEKFILEPPGYEMTPIRVPENSVFVMGDNRNNSYDSHVWGPLPLKNIIGRSVFRYWPPNRVSGTVLEGGCAVDKQ
The following text describes a protein:
Function:
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MSTAGLPFTVLAMCSLSCWYRALAAETTSIGKAVNVKWSSINGKTIIEWEPKPTNYTYTVEVAGEGANWKRKCIHITATECDVTDLLENVKDKYTARIISDVQDAEDFTEEFPYTDSPPFVPYEQTIIGKPVIDSYNFSKDDTKLTVIIKDPFTPYRFSNGSFKSIREIFNNDLKYTVFYRRASSTGKKQETSSSNEIVINVDQGESYCFYVQATIPSRSQNRDSQVSDEKCTTSNKNELDVTVLVAVIISVVLIVLIVIALSVMLCKRKRAKPDKASDNDML
The following text describes a protein:
Function:
Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion. May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum.
Subcellular Localization:
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Sequence:
MCDTVDSGTQVAIHELGNRDGEDQGWREDIKQGCSRFLRSCCTVKTAKTRLPILTWLPTYRLAWLFRDFVAGFTVGLTVIPQGLAYAALAELPLQYGLYSAFMGCFVYCVFGGSRHVTLGPTAITTLMVAEYVNGEPVYAVVLCLLAGCVQFLMGVLHLGFLVNFISFPVLAGFSSAAAITIATSQVKLVLGLKNIPRSFIKAVPTIFQKITHTNLSDMGMGIVCFVVLIVLKKLKEVDWDKKKGTLQKPPLWQKILRKVLWLFGTVRNAVVVVAASLVAYGLLTRGISTFTLTKEIKPGLPAFQPPQFWLVKNGTVVKNGPEIIQDIGVGLVIVPLIGFLESIAIGKAFARKGNYRIDATQELIAIGVTNMLGSFVSAYPVTGSFGRTAVNYQSGVKTQLGGLFTGILVILALAFLTPSFKYIPSAALGAVIISAVIQMVEYSVIPVFWRVKKLDLLAFFVTFFGVLLLGIQYGIALGVGVSLIILLYPSARPRATVYPASIAPDDVLIVQLESGLNFPAVDYMRDVVAKDAFKEKPYKNVVMRCCCVSDIDCTVVQALDQLIEEFEARGLKLHFSCMRPDIRAALVRSKIKGFRYFKTCEDAIAAMRAVSEPDQENGEVIMTDHALLSNIDTPDDDTPGNTPDNVPCTIHIPAVNVSKVTAV
The following text describes a protein:
Function:
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLSRFCNTGWRVLLFAKSTHTGSTTSCNRRFLSQSSRLNYRKPFSASLIRGERDKKQPEGFPEKDDHEKHVNSEENDKSNEQPIRKTEETASSQNDTTPQDGEEDGEASAGSIPEVYPQLMVLPIMRRPLFPGFYKAVVTKNPVVSAAIKELVKKRQPYIGAFLLRDEDKDTDVITDIKQVYPVGVFAQITSIFPAKNAGENALTAVLYPHRRIRITELIPPKSTQEAVKANVKDIENEQQEETKEEEEPEQPHQSAEDSTALLPNKDEQSLLVPDENTPGGTPPSTSSSVPKNDYLPLQNASAILKNFNVSLVKVQNIPKEPYDRQDPVIKAVTSEIVNVFKDIANLNPLFRDQIANFSISQSTGNVFDEPEKLADFAAAVSSGELDELQQVLEASNVADRLQKALFVLKKELFNAQLQSKISKDVDQKINQRQKEFYLMEQLKGIKRELGLETDGKEALVTKFRERTKDLRMPPEVEKVFNEELSKFQHLEPVASEFNVTRNYLDWLTELPWGRKTTENFNLERARTILDEDHFGLKDVKDRILELVAVGKLRGTMQGKIICLVGPPGVGKTSIGRSIARSLNREFYRFSVGGLTDVAEIKGHRRTYVGAMPGKVIQALKKVQTENPLILIDEIDKVGKSHQGDPASALLELLDPEQNSAFVDHYMDVPVNLSSVLFVCTANTLDTIPAPLLDRMEVIELSGYVLDEKINIAKGYLIPQAKEACGLKDTNINITDGAIKGLIRYYCHESGVRNLKKQIEKIFRKMSFNIVKKMGEEKLPEEAGVTKEGSEALEAQSEQVSEHATSFKPRVPIKIPEVINLTITDNDLKDYLGPATFLSDRLYDITPAGVVMGLAWTRLGGATLYVESIVKNKLTSSSQPSLERTGQLGDVMKESSLLAYSYVRSLVAKRFPDNQFFQKAQIHLHCPEGAVPKDGPSAGITMATSLLSLALNMPVAPDIAMTGELTLTGRILRIGGLREKAVAAKLSNVKKIIFPKDNLSDWEELPPYVKVGLEGYPVEWYEQMFDIVFPTATYEKCNSLWPELLKEDTVQKSSRVTAVVN
The following text describes a protein:
Function:
Member of the two-component regulatory system EvgS/EvgA. Phosphorylates EvgA via a four-step phosphorelay in response to environmental signals.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKFLPYIFLLCCGLWSTISFADEDYIEYRGISSNNRVTLDPLRLSNKELRWLASKKNLVIAVHKSQTATLLHTDSQQRVRGINADYLNLLKRALNIKLTLREYADHQKAMDALAEGEVDIVLSHLVTSPPLNNDIAATKPLIITFPALVTTLHDSMRPLTSPKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGHNDYFIGSNIITSSMISRYFTHSLNVVKYYNSPRQYNFFLTRKESVILNEVLNRFVDALTNEVRYEVSQNWLDTGNLAFLNKPLELTEHEKQWIKQHPNLKVLENPYSPPYSMTDENGSVRGVMGDILNIITLQTGLNFSPITVSHNIHAGTQLSPGGWDIIPGAIYSEDRENNVLFAEAFITTPYVFVMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIQVDNASAAFHKVKEGELDALVATQLNSRYMIDHYYPNELYHFLIPGVPNASLSFAFPRGEPELKDIINKALNAIPPSEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKVIQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENSDSPFKDVFSNAHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASDNAVYICGWQDITETRDLINALEVEKNKAIKATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSSTFPEHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLGHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPVEISQQVATVEAKAEQPITLPEKLSILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFELTRKLREQNSSLPIWGLTANAQANEREKGLSCGMNLCLFKPLTLDVLKTHLSQLHQVAHIAPQYRHLDIEALKNNTANDLQLMQEILMTFQHETHKDLPAAFQALEAGDNRTFHQCIHRIHGAANILNLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEIAVFCQKND
The following text describes a protein:
Function:
Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFARTFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIKDTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKIL
The following text describes a protein:
Function:
May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. May also be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAQPFEDWYKNLPIVTKIYMTGCVVTSVSVYLGLVGPLRLYLNFPLVFGKYEFWRLFTNFFFYDEIGMNFFFHMYFLVRHSRLLEESSFRGRSADYLFMWIFGSFLLLIMDAFLFYTKIVTKVLFLAPSIAFMVIYVWSRRNPNMHISFLGLFTFSAPYLPWVILIMGYLFNHDLTTDLLGAVAGHAYYFLEDAYPLISNRRLLKTPGFLKNLMDGQEQPIVDAHQQQEVQQAQQQEVQQPVQNFLNEDDLDQQ