lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MRSSLAPGVWFLRAFSRDSWFRGFILLLTFLIYACYHMSRKPISIVKSRLHQNCSEMVRPVNDTHDLNDTTWCSWSPFDKDDYKELLGAVDNAFLVAYAIGMFISGIFGERLPLRYYLSAGMVLSGLFTSLFGLGYFWNIHMLWYFVLIQICNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNILGSLIAGVWVNQHWGLSFIVPGIITAIMGVITFLFLIEYPEDVDCTPPRHHDDPEKEQDNPEDPVNSPYSSRESNVDIAASSSKEQGPEPEAISFLGALRIPGVIEFSLCLLFAKLVSYTFLYWLPLYIFNVAHFSAKEAGDLSTLFDVGGIIGGIMAGLISDYTNSRATTCCIMLILAAPMMFLYNYIGQNGITSSIVMLIICGVLVNGPYALITTAVSADLGTHESLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLISPTGWNNVFYMLISADVLACLLLCRLVYKEILAWKTACGRSSGYKQI
The following text describes a protein:
Function:
Essential for the assembly of the distal half of centrioles, required for centriole elongation. Acts as a negative regulator of centriole elongation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Sequence:
MPDGAIGQHEGFLHDVGCNVDVYTSRMREDILTMLGRYVNQQHQSIKESLHAEAVRRENAILDERRKIEVTAVGALREVERQKETMSRLVGGLGNANRRMWMQKRFHDWELWVLRKRHRKKLYKTIECHINGIRAYHVYTQWRLLAAARRHHRLAVAEQSQWKCSEAELVGQLEVLNKVIEEERRHSENLEEKMRTAFVRGVCALNKEAVQVLKGAQLADPQASPLCPGGMRATRTSPPRYGATRGVSNIFDGSTFHTGAGTTMTAGRTADAEDATPLTGQFLPEIRDCSPTPTKTTPARVTPPRHHACYAPATCAYSARTLPHQPFVVSVDPAAVRSYGDVPASKKPPYVARRPPMGFGSRSTR
The following text describes a protein:
Function:
Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA. Probably participates in beta-oxydation and energy production but could also play a role in the metabolism of specific fatty acids to control fatty acids composition of cellular lipids in brain.
Subcellular Localization:
Mitochondrion membrane. Peroxisome.
Sequence:
MGGGRGGAAGLDLQVLDRHLSRHLPGFALPPAPPLTVSRYRSGQSNPTFYLKKGPKAYVLRKKPHGSLLPKAHKIDREFRVLKTLFSNGFPVPKPLLYCDDASVIGTEFYVMEHVQGRIFRDFTVPGITPAERSALFVAAVETLAQLHSLNLKTLDLEGYGRGIGYCKRQVSTWTEQYRATAHQDIPAMNQLSAWLMKNLPANDNEENLIHGDFKLDNIIFHPKEARVVAVLDWELSTIGHPLSDLAYLCLFYFWPKTIPIPSVEELISIYCRCRDISPTLPNWNFFLALSYFKMAGIAQGVYDRSIRGNSSGENSCLFDSVVKPLAEIGLQLSQKTFSTSVPPTHTTEGLFPRTKRGKEILMKVKQFMKKHILPAEKEVMEFYTCNENSLDKWEQPFVIDKLKEMAKAEGLWNLFLPAISGLSQLDYALIAEETGKCFFAADIFNCQAPDTGNMEVLHLYGSEEQKKQWLEPLLQGTIRSCFCMTEPDVASSDATNMECSIERDGDGYVIDGKKWWSSGAGNPKCKVAIVMGRNKNSSSSRHQQHSMILVPLSTSGVKLIRPLSVFGYLDNIHGGHFEIHFNKVRVPASNLILGEGRGFEIAQGRLGPGRIHHCMRSIGLAERALQIMCERAAQRVTFKKKLHAHEVIAHWIAESRIAIEEVRLLTLKAAHSIDTIGSAQAKKEIAMIKVAAPRAVCEVLDKAIQVCGGAGLSQDFPLANMYAIVRSLRIADGPDEVHLSAIAAMELRDQAKQLVAKM
The following text describes a protein:
Function:
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
Subcellular Localization:
Cytoplasm. Nucleus, nuclear pore complex.
Sequence:
MDEKMSVLEELGRTSKGRLRYSKDVEIGTKSGDAAGWLGRLVVRINDVDQVLSALEAELQNEQNGESPRSKTQEGLSPPNKPSQRGTQHKETIHARPQASQDLSPKIIPPAKGPTGSSENGGDIVRAQLQKSVSVYEQERQETVKETVVKQKIQMEQQIAGLWQQAQQQLSILQDQHRLNSRRQQDKVNNLLLHRGEKSQQRIQQLEEDHRQRARHLDAQLQEAIVRQTQQQRRKQAYALEKLRQLIKQQEESNEAAQAMTTLLSDFGQKDALPADVLSDAHRAMMLTSNLTRQVSAASQAGGTTDQVLQLAQTTLAEVKAIKTKVVQAVEKAREEARKADEERARQAQEQARVQAAEQEKQAALKQAEKATAEKAAAKTSSTKPAVPADSKEAFLSTYTQNIKRYRDLQTNLDTCVQSCLPLAKPTDSQLKKYAFDLQKAVNTPLNAISSHSASHVTDKLERLCRLLQGQQVEVSDKRVSATSHPMATLYCKELLARKFMKQGIEQIASNHESAFPIAAVAVGVWMEFPDVGELLMAHFHRACPYIVPFYPPRLDGQSDEDFYKSKGYAYKEGTVEKQDKFLKRMSGIMRLYAAIVQTDTGSKKHPHGVAHGWCWLSSVINLDPEMDVTATLLYDFLQVAGHALMKTYGKQFHKLLHILCRDYFTQIQAVTGAGQGGPVSRLKGLLEECIKTQRIATPKGMLTSVFWTS
The following text describes a protein:
Function:
Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
Sequence:
MGFTLLIDNYDSFTWNIYADLASVGGNPYVVRNDKITLKEIEGMFSDGELERIVISPGPGHPRTDSGVSRDVIAWGMGKLPILGVCMGLECIVDLLGGEIAYAGEIKHGKTSLVQHDSIGVFHNLPQFLSSTRYHSLSAQIQSLPSVLQVTSTTKESGVIMGVRHRTYTVEAVQYHPESCMSEGGRGLMANFIQMKGGKWGGENAWCGVPAEGEEEQPKAKTNGAPSLPTILNRIHAQRLLDVEQAEKVPATSPANVSTSLSLYASPPLINFRDRMVSTPHTAVMAEIKRASPSKGDIAPTASAPEQALKYALAGASVISVLTEPTWFKGSLLDMLAVRNAVDSLPNRPAILRKDFVLSKYMIDEARLYGADTVLLIVAMLEPQQLKELYDYSVSLGMEPLVEVNNPTELSLALEIGSKVIGVNNRNLHDFNVDMSTTSRVNAALNGRDVVLCALSGISSHEDVEKYVKEGVKGVLVGEALMRASDTKAFLRSLIGLPPLEVVPKSRPLVKICGIRSTDDAKLAISAGADLLGVILVPGTKRCISTSTAREISALVQSARSQSSSKPLEPSLSSPWFTTQSDLLSSRRKPLLVGVFQNQSLSDILSAVEEIGLDLVQLHGDEPQAWAKFIPVPVVKVFRVSPEGIVRGGEFRRPGLNQAILLDAGGVSGGGGEGKAFPWEHAKRLIQSGEVGSEGHMPLPVILAGGLTPENVGQAIEQAGEGVWCVDVSSGVEGEGGKVKEKVEAFVKAVRG
The following text describes a protein:
Function:
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTLAGIFIGGGLGAMLRFWLGNVITAKTKGLSLPIGILTVNILGALGLGIFTGLHVANASVSLIIGTGFFGAFTTFSTFSVETIQLLMAKRVKESILYIVLTLCGSLFAFWCGWTITI
The following text describes a protein:
Function:
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
Sequence:
MHGRKKVPLDEAKKLEQKKAIAYIREEYEKVMDAQAHPEKINEVVESKTPILTRLDDFATCWNMRKKYFKEHATKEQLDIELEISENVIRSNPKSYWAFHHRRWCFEYMNITELDHEIQLCTLLLNADFRNFHAWRHRRWAVKRMGNKYEEELQNSYDFIQKDFSNYSAWHYRSQLPNLTDFKAELDIVQTCIYMDANDQSAWIYLRWLLNHEEIYNDAETLEQLESSIEELQEMEPNAKYVLLAQIWVLQKMKEVDQEKIAKITDKLVQLDPIRAPYYREITHTN
The following text describes a protein:
Function:
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
Subcellular Localization:
Cytoplasm.
Sequence:
MNRYELAQKIDHTLLRPNISLLDIERLCNEAKEFGFYSVCINPYYIPYAKELLKDTKVKICTVIDFPLGASTTSMKVYQVRESLKLGAEEFDMVINIGALKDKKRDYLISEIREVVKAAEGKVVKVIIETCYLTDEEKIYATEIIKEGGAHFVKTSTGFGPQGATVQDVRLLKSIAGNDLKVKASGGIRTFEQALEMINAGADRIGTSSGVSIINGLGK
The following text describes a protein:
Function:
Calcium-binding peroxygenase involved in the degradation of storage lipid in oil bodies.
Subcellular Localization:
Lipid droplet. Microsome membrane.
Domain:
Transmembrane regions are predicted by sequence analysis tools, but these regions probably constitute hydrophobic domains associated to phospholipids; The proline-knot motif may be involved in targeting to lipid bodies.
Sequence:
MGSTSDPSPSIITVAAEAPVTAERKQNLHLQEQLAKPYVARALAAVDPAHPNGTEGHEHHNMSVLQQRAAFFDRNNDGIVYPWETYQGFRAVGFGVLTSILGGFLINLGLSYRSQPSWIPSPVLSIHIKNIHRCKHGSDTESYDTEGRFEPSKFDAIFSKYALTQPDALTSEEISTMLQVNRNLLDFIGWVASIAEWRLLYQIGKDEDGLLHKETIRGAFDGSLFERLEKDRASRTKIV
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion outer membrane.
Sequence:
MADLMNSDVFLAFCTYATIVILKMMFMAPLTGYFRFTRKAFSNWEDTAMSKNPEARKKMLQTNPDVERVRRCHLNDLENIIPFVVIGLLYALTGPDLSTALLHFRVFVGSRFIHTASYVLALPQPSRGLSWVVGMITTFSMAYRVLTTALYL
The following text describes a protein:
Function:
Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (Probable). Other sugars are not used as substrates.
Domain:
The N-terminus (about 270 residues) binds NAD(+) and GDP-alpha-D-mannose and is joined to C-terminal domain by an exposed linker.
Sequence:
MRISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQTGRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVVVRSTVLPGTVNNVVIPLIEDCSGKKAGVDFGVGTNPEFLRESTAIKDYDFPPMTVIGELDKQTGDLLEEIYRELDAPIIRKTVEVAEMIKYTCNVWHAAKVTFANEIGNIAKAVGVDGREVMDVICQDHKLNLSRYYMRPGFAFGGSCLPKDVRALTYRASQLDVEHPMLGSLMRSNSNQVQKAFDLITSHDTRKVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYELRIFDRNVEYARVHGANKEYIESKIPHVSSLLVSDLDEVVASSDVLVLGNGDELFVDLVNKTPSGKKLVDLVGFMPHTTTAQAEGICW
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKKTTAEDLHRAWFVLQTRVNAHLDQGLCRIFKDSLPGVKQTIEKKEGLLRKNMMGKRVNSAARSVISPDPYLDCNQVGIPVEFAKRLMFSEVVHPRNFEELREAVINGPDEYPGAYSVQLENDQLISLHAKTRAQREAIANQLLTPTIINGYPSTDKKKVKRHLKTGDKMILNRQPTLHKPSMQTFSARVLPMEKTIRINYTPCKAFNADFDGDEMNAHFPQNEVARAEAFVVACAEEQYLVPKDGKPIAGLIQDHMVSGVLLTVRGRFFHRMQYQQLVYAALSNSQANIKLLPPSVYRPVCLWSGKQVLSTLLLNVIPDDKPALSLKGKSKISDQVRKKLMEQVENKLDPSYPFMSESDVLIVDGELLQGVLDKNHYGASAYGLVHWCYELYGGEVSSRLLTCLGRLFTYFLRSQHSFTMGVEDIIITEQGDKERIKKIKEVKECGQEVVARAMQLPAWADPQQIVDGLKRVQFSKKRMDLLELDGAINTQMTQFQDKIKKSCWPQNLIKSFPSNNLTLMVQSGAKGSVVSLILSYDTCARATLPSFKPYDLHPRAGGFIDNRFLTGLNVQEYFFHCMAGRDGLVDTAVKTSRSGYLQRCLIKHLEGLTSAYDETVRDSDGSIIQFKYGEDGLDVMRTSFLEKKHFSQLIENQYSIVNKELEAEIFSKINTVDALQHHLKMEEWRSTHENFTRKTAFQLFSERHWDEVRERMMMMRRVQMDGANQAFIERQLDEICKEELSNMFDNMNDKQSRRLQKKLMTCPDPVSSILPASRYLGCTSQHFHDVLEEYIKRDDNKVSAMRHPYKITTDDLKKMMYLKYQRSLIQPGEAVGILAATSMGEQTTQMTLNTFHFAGHGAMNVTLGIPRLREILMVASKDIKTPMMMVPLLSLGDKAERRVNKFIKKFRRVPLEKVLSSAVVKKTLIVSEFKKGHRLYKIRFNVAPHSLYKDDFNLNPAKILNYLESKFMGHLARVIEKQERELVASSDDDDDDDDAAAADDSGDDGERKRRADQDADEEEDDEAGDDDDDDGNDEGSGDDDGDEDGEEDGKEKADENSKKKKPTKNRSKNNEDDDDDDDDDDNNNKNNNNNDEGGDNDDEMTEKKKTKRRKAVCSKSHVIDYVYDVQDNMWGEVTFKFELAKKEMDIQWLVDSEIKRTVINQVANISNCIMKEIDINDSPAYMFESALNELERMTSRGLLCGRRKKLQVEGLNIQEMYKYQDRLCVDELYCNNIQAIALNYGIEAASQVIIEEIRQVFKAYGIDVDYRHLSLIADYMTYEGSFRPFNRLGLDSNASTLQKMSFESALNYLKKSIVDGSHENAESPSACLILGKPIKTGTGSFDLVVPVS
The following text describes a protein:
Function:
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MGDHEGRGDDFEKKADQKLSGWGLFGNKYEEAADLLDRAGNFFKLAKNWSRAASVYKKIADCHLQGDSKHEAASAYVEAANCYKKFSPQDAAQALNNAVNLFLEIGRLNMAARYSKDIGDIYQQEQDLENAAVYLNRAADLFDSEGQSSQANSMTQKIAEIYAQLEKYQKATELFEEIARKSINNNLLKYGVRGILLNAGLCQLCRGDTVAINNSLERYQDIDPTFSGTREYKLLADLAASMDEGDVDKFTDAVKEFDSMTRLVQSIGNFSVFSFIIWAGASSRVVYYLR
The following text describes a protein:
Function:
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
Sequence:
MAAPGDGAISINALKVRMQEVSEELSKYKTLFEASEKELEIEKAKTKALESEARELNHKVSLMENEYDQQAAKYVLLCEKLEETIKVAEECDKQRKLLDQKRVVDEERLAELEQIFRETSEIAFESEKKYDEVSRKLAASESDLEKDLAKTEAAELNVKNLQDDLKTMSAKLKSMQARVDKAATKEANFDKTIEDLRNQLKTCIKIMFQAEDCGNEADKTTCKLQRELDQLQDHLLQIKMQCQVLKHESDPRDISFN
The following text describes a protein:
Function:
Component of a regulatory phosphorelay system that controls B.abortus cell growth, division, and intracellular survival inside mammalian host cells. This signaling pathway is composed of CckA, ChpT, CtrA and CpdR. ChpT efficiently and specifically shuttles phosphoryl groups from the CckA kinase to the receiver domains of both CtrA and CpdR. Does not bind ATP. Overexpression of chpT results in a defect in cell morphology, DNA content, and intracellular survival in human macrophages.
Subcellular Localization:
Cytoplasm.
Domain:
Each ChpT monomer is composed of an N-terminal dimerization and histidine phosphotransfer (DHp) domain and a C-terminal domain that is structurally similar to the catalytic and ATP-binding domain found in histidine kinases but that lacks regions required for ATP binding.
Sequence:
MSLPVTLSALDLGALLCSRICHDIISPVGAINNGLELLEEGGADEDAMALIKSSARNASARLQFARIAFGAAGSAGVQIDTGDAQNVATEYFRNEKPEFTWEGARVLLPKNKVKLLLNMLLIGNGAIPRGGSLAVRLEGSDTDPRFVITVKGRMLRVPPKFLELHSGAAPEEPIDAHSVQPYYTLLLAEEAGMKISIHATAEDIVFSAE
The following text describes a protein:
Function:
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MRIAVPNKGRLHDPTLALLDRAGIGVEDGADRQLYADTVDPALTVLYARAADIPEYVADGAADAGITGHDQLRESDVDCVEERLDLNYGSCRLVLAAPEDGDVTAPADLDGATVATEFPTITRAYFADTTATPEIVEVTGATELTPHVEMADAIVDITSTGTTLRVNRLQVVDEVLSSSVRLFAHEDVHDDPKVQQVETALRSVLDAHGKRYVMLNAPADRLDDVKAVLPGLGGPTVLDVDEPGTVAVHAVVPERDVFEAISELKAVGASGILVTEIERLVD
The following text describes a protein:
Function:
Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.
Sequence:
MFQPVSCCKLVMLKLLNPGKNAENGFRYFSRTAISYKSKSKQSKIRDINRDVNVNVSTPEDFIYDLKQKLQGIPEKLTSTLKVMATDSQQGNVNQLEHVMVSKPKQEEHLLKDIAAISRVSGKVLNIKPYSPQDVKYIMKAITSSNLRMQPVLKDSVTIQVRLQETTLETLKALAKQIKEQEDRTKVAIRLVRTSFQKKLARRKLSKVWSEDECRKVEKDMQDTIQAQNGQLTTIIERYLKQLKEQSRNKPF
The following text describes a protein:
Function:
Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that TtgR binds these antibiotics.
Sequence:
MVRRTKEEAQETRAQIIEAAERAFYKRGVARTTLADIAELAGVTRGAIYWHFNNKAELVQALLDSLHETHDHLARASESEDEVDPLGCMRKLLLQVFNELVLDARTRRINEILHHKCEFTDDMCEIRQQRQSAVLDCHKGITLALANAVRRGQLPGELDAERAAVAMFAYVDGLIRRWLLLPDSVDLLGDVEKWVDTGLDMLRLSPALRK
The following text describes a protein:
Function:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
Subcellular Localization:
Nucleus.
Sequence:
MATNEQPKAANEEAKIDLFEDDDEFEEFAIDQEWDVKEEGNEVTQQWEDDWDDDDVNDDFSLQLRRELESNNEKKFRCDCFSVGCGGPKKELKKDDEDVKNHKK
The following text describes a protein:
Function:
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDYLTMFYDGWRDLMDNKSDPRTRDYPLMSSPFPTIAISLTYAYIVKVLGPKLMENRKPFELRKVLIVYNAAQVIFSAWLFYESCIGGWLNGYNLRCEPVNYSYSPKAIRTAEGCWWYYFSKFTEFFDTFFFVMRKRYDQVSTLHVIHHGIMPVSVWWGVKFTPGGHSTFFGFLNTFVHIFMYAYYMLAAMGPKVQKYLWWKKYLTVMQMIQFVLVMVHSFQLFFKNDCNYPIGFAYFIGAHAVMFYFLFSNFYKRAYVKRDGKDKASVKANGHANGHVKALKDGDVAPTSNGQANGFHNTFSKFTTDMCNPALNSSTRQRVLVNAGNK
The following text describes a protein:
Function:
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
Sequence:
MTDQKHPLLAGLQDATPLANWSSTELSNAAVEIRDVLCNLLATRTAHFASNLGVVELCLALHSEFDFRTDRLIWDTGHQVYPHKLVTGRYDRFETIRTAGGLMGYPNPHESVYDLFMTGHAGCSVSTAVGLRSGDILMDQKDRRTVAVIGDGAFPCGVVFEALNNAGELGDDLTIILNDNKMSICHRTGSVAQYLDRLRGNPFYTGLKHEVTKLLDRVPMFGDPAERLLAQMKEGVKAGLLGGMLFEELGIRYIGPIDGHDIPLMQKYLRLCKETPGPVLLHVVTEKGHGYKPAAEDPVFFHTPPAFEDRGGTPVTRGSDGRPPYTTHARDAIGEAMKRDSRVTVITAAMCQGNKLEPVREQFPERFFDVGICESHAVAFAAGQCKTGMRPIVDIYSTFLQRSYDQIFQEVALQDLPVVFMMDRAGLTAPDGPTHHGVYDIGYMRLFPNLVLMAPGYAEELSMMLDKALTLDHPSGIRYPKASALEATHTPAPIEIGKAEWIREGTDGTIVAYGAMLEQAIAAAEQLEGELEIGVVNARFVKPIDAEMVHKTLSDGRFVVTLEEGTRVGGFGSAFLESAVDQRLDTRAVHRLALPDEFVLHGDRSQLLDQSTLSAQKIAEVCREAASEVGSQVGI
The following text describes a protein:
Function:
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
Subcellular Localization:
Peroxisome.
Sequence:
MHCIKELEISVHIKLDTMNEYLHSDNTKVIPTDTIKNSIEALAKIRGINTIEQFGLDICDHFLTSFCHVVYCNAFIQEVPWQRLEKDGTPHVHAFLYSSEGVRFCEVEQSVDGAPIVFSGIKDLKIMKTTQSGFQNFYKDKYTTLPERRDRILSVEMLIKWCYGVCPEGLDYDCIWRTAHESALDAFAGPPETGHYSPSYQKTVNCVQEYILEKIPQVEEVEVICSNIHYSLTPLEKLGLCNDKEIFTPQDTPFGACASTLRRKKGPEEECDTVVESKTHCSAGWKPALKSN
The following text describes a protein:
Function:
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Sequence:
MKTLFFSLFSLFSVFSHFFSPLISPFYFSFALLLFLFLFLPFFSLSFLILSLCRLTAPKIPEGEKVDFDDIQKKRQNKDLIELQALIDSHFEARRKEEEELVALKERIEKRRAERAEQQRIRAEKEKERQARLAEEKARREEEDAKRKAEDDLKKKKALSSMGASYSSYLAKADQKRGKKQTARETKKKVLAERRKPLNIDHLNEDKLRDKAKELWDWLYQLQTEKYDFAEQIKRKKYEILTLRCRLQELSKLLSLSGTGLIRLRNTARRQEPKARLAGAGSKDPGRMALSDVPKPCWSLPSSFTNHLCSRASVITKIATSACVGYCCCFSSSWRGLVASSVKGKQVPCGTVETPCWHLQFLLSMSFILLTPALCCPVDCCVQISGFCK
The following text describes a protein:
Function:
Seems to be involved in regulation of DNA repair correlated to non-homologous double strand breaks (DSBs) repair. In vitro, involved in rapid but not in slow DSB repair mechanism. Required for effective immune responses that involve activation of DNA damage responses.
Subcellular Localization:
Nucleus.
Sequence:
MLKKKLSLEDEDDDRSYNLRSSRSNAKSKPRSSAGTATNPRASKRARLSGASATQEDSSLVDKIRLSFEDFDEALSGFKVSSGYERSKNTDLWVDKYRPRTLEELSVHKKKVDEVKLWFQESLDFLKNGLRNNVLLVTGQAGVGKSATIHLITSILGVTVHEWNAPIPTIWQEHVHNTSSGLKYTSKLDEFENFVESTRKYGVMASSSTDGIKAPVVLLIDDLPLANGRHAFERLQNCLLLLVKSTQIPTVILITDHNNADSSDQTARRMEDTQSSLERAGALKVAFNPITKNSIKKVLQRICREEHCKVTTMEIDQMATASGGDIRHAITSLQLFSVKPELNHTKIKSPRPGMEDNYHGNEQTMYSGLDSGISSCFGRDETLSLFHALGKFLHNKRETDNVIISECSSSLVHDEFARLPLKMDAPEKVLSQAHGQAGRVVDFLHENVLDFVSDGAIEDAWCVSSYLADADLLLADIRGKMSGHNNTEDVPQSAGASVAVRGVLYGNKQPCSSRWHVIRKPKLWQVEQSSIQTKKNLREQRNISYEGSRVADISVMATEYSPVLKWLSYRASPDAFPGMGEETDEEDSDISEDDEIQDW
The following text describes a protein:
Function:
Required for peroxisome inheritance.
Miscellaneous:
MISCELLANEOUS: Present with 639 molecules/cell in log phase SD medium.
Subcellular Localization:
Peroxisome membrane; Peripheral membrane protein.
Sequence:
MVLSRGETKKNSVRLTAKQEKKPQSTFQTLKQSLKLSNNKKLKQDSTQHSNDTNKSVKAKKNGTSSKKTGTQRKRISTQRFSLFTYGNVQVMNSFVPIHNDIPNSSCIRRNSQVSANNVTESSGVFFNDTQSQDSQNTIKLKPTSLMAKGPIEIYQICTGFDKLKENIAPFQKSSKASSHDGHVVNYLSIGRHGDIVHPVLPKLQITRLNGAGFKYFISFYNPERYWEIEFLPLISQSQSELENSVKAFENVISKICQFSHINEGATIGNNESLSDKFKLPPTSDIEPPNTEIINNDDDNDDDDDNYDDDDLNYLLDEEYEQGCTDNSFSVISNTCSNLNASFLYPSDPTDAVSISINEAFKNAIRRTAPVLNIPIAAPSIHSKQQNKRYSSYPFIDSPPYLQDRHRRFQRRSISGLGDL
The following text describes a protein:
Function:
Activates genes required for amino acid biosynthesis and acts as a master transcriptional regulator during amino acid starvation. Binds variations of the DNA sequence 5'-GAT[AC]GC-3'.
Miscellaneous:
MISCELLANEOUS: Functional homolog of the S.cerevisiae GCN4 and mammalian ATF4 bZIP transcription factors.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MNYNDTTEFCFPFGQPSFPTSAMTEGSFDGQFSEFDPTFTSPADTALSDIANLPIDLHKDALFANAPGKGDVDFDSVSMLQLLSDYPLAFNSTENNQKLQTNPSARWSLLDSMDFDNQRQCSDLESAQLGDSGLLKSTILSNSHIDIAALSSSKTSEPTPPFSYVQTPCIPTPSSALIDTPFPGALDSEFGFDESQAPLFPASDGDCQRAFASISYPTNYGCKLSNLGFMSPQSPVKRELNDSTSPSKLSESSSSLTGSSSALLSQSEFLGSVPSLSDSIATVDPFFSFESFETDEKARSLLMDASLKLPQFSTPNLSSNSSSLSLKSTLAEGMKGSTPLAAVKTEKASKAARVMKQKKHREHVCFNCGVTETPLWRRTSDKLNFLCNACGLYNKQYGVMRPLSPRNKGSSKALENLVCANCSSTKTSLWRKDRHGQTVCNACGLYARLHGHNRPIGLKKNKITRRRRGKGPGGEDGMSDEVKSEFPVLSKSVTMAEILSSKGLESPQLTNSVSVSKMPNTDADVSLEHAKISFDSLDNSVIVKKEEEIENKFSVSC
The following text describes a protein:
Function:
Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B.
Subcellular Localization:
Membrane.
Sequence:
MNTFYIFFLFVLTTCFVKGDLPIHALMGDVSGIWKIKQTKKMSQKPEHCGGGIPNRNLDNLNPSIRNYQRFLENEYGNLDMMIVNLTMEKVKIINQEKPRDKWTYLAVRDYERNEIIGHWTMVYDEGFEIRLNGSKYFAFFKYERKSNAHCPTSIEDKSYNDRDCYKTNPTQTHIGWVLNEKVKENTKEKIFYWGCFYAEKKESTPVSSFVLHNGMENKTNLVESHDYHFEEKKKKNLPPIGRRSNYKKFRFSNLQKIYGSTQTHLRDIYGRSGERKYGCRKRDILNLKIRLTLPKQFSWGDPFNDENFEENVDDQKDCGSCYSISSVYSLERRFEILFWKKYKKKVNMPRLSHQSILSCSPYNQGCDGGYPFLVGKHMYEYGIIPEQYMHYENNDYNNCIMDMGNYNHLNKQNRNIKEIYYVSDYNYINGCYECTNEYEMMNEIILNGPIVAAINATSELLNFYNIEDKNVVYDILPKDTHQVCDVPNKGFNGWQQTNHAINIVGWGEQIINQDKIKNDDANNNNNDNNHKLVKYWIIRNTWGKNWGYKGYLKFQRGINLAGIESQAVYIDPDFSRGYPKNILQSDSLE
The following text describes a protein:
Function:
Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid (ABA) biosynthesis from carotenoids. Required for ABA accumulation upon drought (Ref.2). Required for ABA-mediated regulation of anther/pollen development, including metabolism, cell wall modification and transcription level. Positive regulator of fruit ripening involved in the biosynthesis of abscisic acid (ABA); initiates ABA biosynthesis at the onset of fruit ripening. Modulates the degree of pigmentation and carotenoid composition as well as pectin catabolism during ripening and may regulate the ethylene production and action in climacteric tomato fruit.
Subcellular Localization:
Plastid, chloroplast stroma. Note=Partially bound to the thylakoid.
Sequence:
MATTTSHATNTWIKTKLSMPSSKEFGFASNSISLLKNQHNRQSLNINSSLQAPPILHFPKQSSNYQTPKNNTISHPKQENNNSSSSSTSKWNLVQKAAAMALDAVESALTKHELEHPLPKTADPRVQISGNFAPVPENPVCQSLPVTGKIPKCVQGVYVRNGANPLFEPTAGHHFFDGDGMVHAVQFKNGSASYACRFTETERLVQEKALGRPVFPKAIGELHGHSGIARLMLFYARGLFGLVDHSKGTGVANAGLVYFNNRLLAMSEDDLPYHVKVTPTGDLKTEGRFDFDGQLKSTMIAHPKLDPVSGELFALSYDVIQKPYLKYFRFSKNGEKSNDVEIPVEDPTMMHDFAITENFVVIPDQQVVFKMSEMIRGGSPVVYDKNKVSRFGILDKYAKDGSDLKWVEVPDCFCFHLWNAWEEAETDEIVVIGSCMTPPDSIFNECDEGLKSVLSEIRLNLKTGKSTRKSIIENPDEQVNLEAGMVNRNKLGRKTEYAYLAIAEPWPKVSGFAKVNLFTGEVEKFIYGDNKYGGEPLFLPRDPNSKEEDDGYILAFVHDEKEWKSELQIVNAMSLKLEATVKLPSRVPYGFHGTFINANDLANQA
The following text describes a protein:
Function:
Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Subcellular Localization:
Mitochondrion.
Sequence:
MNLHTNNNNNNNNYVDENLFWKVYKNLFIRNLIFYKIISTTVIYKYDDDDSLSSGKFIVPSDRVQFKNIISLSWIVKRNLWSLLKYKLISNEELIIKKKAIELLLQECKHDKDLLKLIYQNKYYQMNQIDLILNSIKHSNLMALKLFIEEYNLPTNNNSMDMALEIASKQYYRNEEEQKQSFEVFQFFWEKKKDTLQCTQSELFNQNRNYNAYMLQLILNNPSLYGESLQSNNNNNNNSSSNNIGLMTSREFFNLAVMSVIPEKIKIELLNRGFVKNEKSIYRDGDYIAKTIQKQSPYLPKSIYSYLEKSYQKNELYENRTISVFYFFKILIEYPEKEDSLSILKDFVNVAYKFTDLEIRSYNTLSLNPNSYKAGQKVEILQAISSFNFTLKIKIIESLFPIDSLTLESTRFIFDRLKSSIDNAGTMKHVSKAELIPQSLYHLNIIKTADVELLDQFLNHFHSDAERNLIFKIDDENPLNKDYFKDCSIQDSEKISKFIDKLSSVKEFNSNSKSFLNCLKSKLLPISSELYISSLLKFKETSRKQTYVHAKVLDETLCDFFSEKNNFKSNLTSFIKFINFRSLSITYLVEKVLFSNDFELIELLLNTICNNNNNYGAGIIMVPVSFKTSNPDIIKLIISKSNWHKLFDFKGLIDTVISDSNVCNISNPNTDSQTIELIETVIDFLHSNKIYQRNSKEGFGFGFGFGTTNQQENHTEKTIISNDATKIALLKKKSIKILQLLLKYKNLFDWDSQLFPKLPKLPTIQLDDEILPKSDKPIMSIYEQQELEDQDLYQSRRRKPKNKHGGGRGRRRIDTYNDTAYDGTNNNIPYIGSIGGSVFASTEDSVNGGGSGFYSSSSSIGSISSISSISSISSSNNNNELGSDQSQFILGGNFTGFSGNYQSKSKDKKKIRNLYNTNFLDKFKTHQAQSIFDTMDQLFTRNYTFSFAYTSDSVFQDSIYHSIKNRRIDVIEKLITIQMFTDNHAKLIYSDFLKRIIRNDDGVDLVTFKYLFSHRFLKIFSTEFLQTMSQELLICAVSECCFHLCHWLLSTDNPCNVYVEFLPFKTTYILNVEKKLSYCASPVFKDYMMKKIKPFIKY
The following text describes a protein:
Function:
Component of the sil cation-efflux system that confers resistance to silver.
Subcellular Localization:
Periplasm.
Sequence:
MKNIVLASLLGFGLISSAWATETVNIHERVNNAQAPAHQMQSAAAPVGIQGTAPRMAGMDQHEQAIIAHETMTNGSADAHQKMVESHQRMMGSQTVSPTGPSKSLAAMNEHERAAVAHEFMNNGQSGPHQAMAEAHRRMLSAG