lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Subcellular Localization:
Cell membrane; Lipid-anchor. Cell projection, filopodium membrane; Single-pass type I membrane protein. Cell projection, invadopodium membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein.
Sequence:
MGPGPRRVPRDPGWMLRALALMVAASGRVAFAFNLDTKFLVVKEAVNPGSLFGYSVALHRQTERQQRYLLLAGAPRDLAVDDDYTNRTGAVYLCPLTALKNDCERMDISEKSDPDHHIIEDMWLGVTVASQGPAGRVLVCAHRYTKVLWSGLEDQRRMVGKCYVRGNDLQLDPGDDWQTYHNEMCNSNTDYLQTGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKDWDLSEYSYRGSEDQGNLYIGYTMQVGSAILHPSEITLVTGAPRHQHMGAVFLLKQESGGDLQRRQVLKGTQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAVYVFMNQAGTSFPDQPSLLLHGPSRSAFGISVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSGGLLKQPQQIIHGETLGLPGLATFGYSLSGKMDVDENLYPDLLVGSLSDHIVLLRARPVINILHRTLVARPAVLDPSLCTVTSCVQVELCFAYNQSAGNPNYRRNITLAYTVEADRDRRPPRLRFARSQSSVFHGFFSMPETHCQTLELLLMDNVRDKLRPIVITMNYSLPLRMPDRLKLGLRSLDAYPVLNQAQAMENHTEVHFQKECGPDNKCDSNLQMRAAFVSEQLQPLSRLQYSRDTKKLFLSINVTNSPSRQRAGEDAHEALLTLEVSSALLLSSVRPAGTCQANETNTVCELGNPFKRNQRMELLIAFEVTGVTLHTRDLRAHLQLSTSSHQDNLQPMFLTLQVDYTLQASLSLMNHRLQSFFSGTVMGEAAMKTVKDVGSPLKYEFQVSPVGDGLAALGTLVLGLEWPYEVTNGKWLLYPTEITIHSNGSWPCQPHGNLVNPLNLTLSDPGVKPLSPQRRRRQLDPGGDQGPPPVTLAAAKKAKSETVLTCSNGRARCVWLECPLPDASNITNVTVKARVWNSTFIEDYKDFDRVRVDGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIIILLWKCGFFKRARTRALYEAKRQKAEMRSQPSETERLTDDY
The following text describes a protein:
Function:
Acts as an adapter to assemble/stabilize a Toll/wek/Myd88/tube complex; required for efficient recruitment of Myd88 to Toll. Dispensable for innate immune response; plays a minimal role, if any, in the immune defense against Gram-positive bacteria and fungi. Involved in dorsoventral axis determination.
Subcellular Localization:
Cell membrane. Note=Localizes to the plasma membrane in embryos when bound to Myd88.
Sequence:
MGVPTSDWIYWCRLCARDDVVYKVRERDDDLVRIISKCFDVEMTLEEPELGSMLCEECYSVIGQLITFSDSVSKVQAIFELLRHSEPQDSQDLDALRLEYGLPPACKQDLEFLDIDDTEDRCSLVEELTISDHSTSPSPDFEAQTVRTRANLKQCNSDPKVLASPTASIPEVETKRSRRQQFAAKRNSKVYTATESDDEEAILDEDEAVSPPPLKRKRGRPKGSGKQKNVDDSDNVTSREPDDNAKSKQDDKTSELSMSPHGSQSSNFVDYPCKICNETFMSFMALRRHKHDMHGGPKKYVCDHCGKGLKTFTSLVEHQLVHTEEKPCICPVCNAGFKNKARLRVHSQTHGEPKFECNVCGKKLQTRAILNKHKYVHTDERRFKCEVCGSGCKNSTALKIHLLGHTGLRPYVCKYCGKAFASNTNCRSHKWKKHPELASKEDETESSRVPVPTLEELRAITREMAKAKQD
The following text describes a protein:
Function:
Functions as a nuclear import receptor for serine-arginine rich (SR) proteins. Regulates nuclear import of SR proteins that are required for proper splicing of the two resistance (R) genes SNC1 and RPS4, a crucial step for their functions in plant immunity.
Subcellular Localization:
Nucleus.
Sequence:
MEHQNAVKEALNALYHHPDDTVRVHADRWLQNFQGTLDAWQVADNLLHDSSSNLETLIFCSQTLRSKVQRDFEELPPGAFQKLRQSLTTLLKKFHKGPPKVRTQISIAVAALAVHVPAADWGDGGIISWLRDEMHMHPEYVPGFLELLTVLPEETFNYKIAARPDRRRQFEKELTSQMEAALSILSACLKISELKEQVLEAFASWLRLRHGIPGTVLACHPLVHAALSSLNCDPLSEASVNVISELIHHTASPSSGGISAQTPLIQVIVPQILSLQAHLRDSSKDEEDVKAIGRLFADVGDSYVELIATGSDEPMVIVHALLEVTAHPEFDIASMTFNFWHSLQLMLTKRESYSSLGSEASIEVERNRRLHIFQPAYQSLVSLVGFRVQYPEDYQGLSYEDLKEFKQTRYAVADVLIDAALILGGDTTLKILYMKLLEANAQTGNNFQDWRPAEAILFCIWAISNYVSVVEAEVMPQVMALLQNLPQQAQLLQTACLLVGAYSKWLNAAPASVSILPSIIRILMSGMGTSEDCAAAAALAFRHTCDDCRKNLCGYFEDLFNIYCMAINGGGGYKVSAEDSLNLVEALGMVVTELPLDQAKGALEKLCFSAASPLEEAAKEDLEKKHARELTVHIDRFAFLFRYVNHPEAVAAEINKHWAIFRVIFDARPWDMRTMESLCRACKYAVRTSGRYIIDTIGEMLEKIQFHYQQHHQPCFLYLSSEVIKIFGSDPSCAVYLKNLIETLFAHTTCLMTSIKEVTARPDIADDCFLLASRCLRYCPHLFIPSPIFPALVNCAMIGITVQHREACHSILTFLTDIFDLEKSVNEEQFVRIRDNIIIPRGATITRILIASLAGALPSSRLDTVTYSLLALTRTYRLQAVSWAKESVSLIPRTALTETESTKFLQALSDIAYGADVNSLIGQVEELSDVCRRNRTVQELVQAALKPLELNLVTAPVS
The following text describes a protein:
Function:
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is involved in transcriptional regulation. Heterodimer of ARP7 and ARP9 functions with HMG box proteins to facilitate proper chromatin architecture. Heterodimer formation is necessary for assembly into RSC complex. Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Miscellaneous:
MISCELLANEOUS: Present with 1360 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Note=Localizes to centromeric and flanking chromatin. Association with these loci is dependent on STH1.
Sequence:
MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGTSHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN
The following text describes a protein:
Function:
Catalyzes the transfer of myristate from myristoyl-[acyl-carrier-protein] (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A. Can probably also catalyze the transfer of myristate to Kdo(2)-(palmitoleoyl)-lipid IV(A) to form the cold-adapted Kdo(2)-lipid A. In vitro, can acylate Kdo(2)-lipid IV(A), but acylation of (KDO)2-(lauroyl)-lipid IV(A) is about 100 times faster. In vitro, can use lauroyl-ACP but displays a slight kinetic preference for myristoyl-ACP.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFRDPILARLGRFAGRLGKSSRRRALINLSLCFPERSEAEREAIVDEMFATAPQAMAMMAELAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAMFHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSEFVDFFATYKATLPAIGRLMKVCRARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHTIARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK
The following text describes a protein:
Function:
Plays a role in pre-mRNA alternative splicing by regulating spliceosome assembly.
Subcellular Localization:
Nucleus.
Sequence:
MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
The following text describes a protein:
Function:
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Sequence:
MQRFTKLYIENNDDDNNNNNENIERSLEGKDAIFSNIIACITIGDIMKSLLGPCSRDKLIINKYNEIIVSNDGYTVLKSIQLEHPCSKMMVELSFSMDDQNGDGTTSVVVLSSFLLRKSLKLLNGSSTNISNNNNSGGIGSGGGSIHPIKIINGFVRASKIAIESIINQSKSFDINTDQGKNLMMQTCKTTLNSKLISHTNPILSKLAIDSILMISNLKGSISTESINIISIQGESVEKSTIYPYFILPHSLITPFYSNSNNNNGDFKILFLNLSNNGNNINNNNNILNIEDNINKEENNIKSIVISLKKKGISMIGILEDLNIPNLNISNLLLSYLTKAKISVLKPFSFEKMKYLSNRLNIPIIFDKSEIIKSDNFKTFKSIKYQTINNENLIHFENHIITTTNNQNDDSCCYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNILPTIILRGTTIMELKETERALHDALCVLRNLIRNPIVVPGGSACEIEASKKINDFFNNSIIITNGNNNNDNTTIINRDELLAMLSFAESLEEISETLCQNSGIDNHLEVVLKLKQIHLENKLNNSKNIGIDLKVNSIGDMFEYGVLETLSNKLAQITMATEIVTSILKIDEIVYYRNLVGKL
The following text describes a protein:
Function:
Component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for cell growth only in the presence of M1 replicon.
Miscellaneous:
MISCELLANEOUS: Present with 11900 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSDIKQLLKEAKQELTNRDYEETIEISEKVLKLDPDNYFAHIFLGKALSSLPASNNVSSNRNLERATNHYVSAAKLVPDNLLAWKGLFLLFRTTEVVPDILSYDEYFDLCGQYADALLKQEQSQVELINDIKLLKKTHPDCQKAFYQHLKPGSLMAETIGRHLSTPQDALLNLIKILSNIETTEIGKTLSQNRLKLKASDPDYQIKLNSFSWEIIKNSEIDQLYNQLVNILADDQKRSEIENQWLEYRIKVLKSMPLDVKKDFFTKVKEMVEDMVLVNHQSLLAWQKYFEWTDYEDLDNMDAPLIIKYFKKFPKDPLAMILYSWLSSKLSKYDIKSLESANKPPEGHKKTEKETDIKDVDETNEDEVKDRVEDEVKDRVEDEVKDQDEEAKEDEEEDLDDIEIGLLEEEVVTVLTENIVKCKNNILAHRILCQYYLLTKEYEAALPYIKNGISLIAYNIKDLGVHLPLTKREFSLDLATVYTYVDAPKDHNAALKLYDNILSGDFSNIQAKMGKGIIFIERKNWKDAMTLLTQVHEQSPNNLEVLSELSWSKAHMGYMDEALAGLDTVIKGIKGMDLRSIDFRALNLWRQAKVYIMKHASINDAKQENVKCAFKLLIQSIKILDTFAPGFSTLGDIYCHYYKDHLRAFKCYFKAFDLDAGDYTAAKYITETYASKPNWQAASSIASRLIKGEKAKAELRSNNWPFRVVGIAHLEKQEESDSIEWFQSALRVDPNDVESWVGLGQAYHACGRIEASIKVFDKAIQLRPSHTFAQYFKAISLCDVGEYLESLDILEKVCQEAATEESFQIGLVEVLMRCSLDLYSQGFLLKSVSIAKDTIERIKIIISELKCENQQVWIYLSQVLRLFIWIESKVDTLPVESLVSIFENSQFSGSEEIDSVDNIKIDTLLDSTTDDNVSIACKFLILASKYSVSDQKFTDIAGTVRASYWYNIGISELTAFITLKEPQYRDAAIFAFKKSIQLQSNTSETWIGLGIATMDINFRVSQHCFIKATALEPKATNTWFNLAMLGLKKKDTEFAQQVLNKLQSLAPQDSSPWLGMALILEEQGDIIGSSKLFAHSFILSNGRSKAAQFMYAKNVLENHINNGDDERDIETVEKLTTASIALEQFFKKSPDSQFALQCALLTLERLHHYENANELANRLIGILEKKFEKTQDERELFNFAIIKGQFARIHLGLGNFELSIENADLSQGIISESSDEKSMKTKISNHICLGLSYFFLNDFDQTLNQFQELLSISKDSKHLVVLIAKVLYDVGESDTKEIALQELTEYIATSGADLLVTLTIAAMSILDDKREDLSIILEELKALPLSKQIIDKHKDAPYLIEEITKRLYRNDTGKQVWQRSAYFFPNNLKVWERLDKNIQRRIASNGQNKVTAEEMSKLYCESKNLRSIQRGMFLCPWNVTAVKALNECF
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MSHFWQQSEPISLDECLLKPTRPTVQSFCKVLTASETNTHGRFSVLRKHATECMPALDMTQPNPTQDLLALDLHGAEWKFKHIYRENDEMRVGVRHQAHQQSSMPSSVISSHSMHLGVFATASHAVQTQARFTVYYKPRFTGTIVGVEDISPQWEDSKWRSLKVDKYLYNINYIINA
The following text describes a protein:
Function:
Probable transcriptional activator that promotes chloroplast development. Acts as an activator of nuclear photosynthetic genes involved in chlorophyll biosynthesis, light harvesting, and electron transport.
Subcellular Localization:
Nucleus.
Sequence:
MLAVSPAMCPDIEDRAAVAGDAGMEVVGMSSDDMDQFDFSVDDIDFGDFFLRLEDGDVLPDLEVDPAEIFTDFEAIATSGGEGVQDQEVPTVELLAPADDVGVLDPCGDVVVGEENAAFAGAGEEKGGCNQDDDAGEANVDDGAAAVEAKSSSPSSTTSSSQEAESRHKSSSKSSHGKKKAKVDWTPELHRRFVQAVEQLGIDKAVPSRILEIMGIDSLTRHNIASHLQKYRSHRKHMIAREAEAASWTQRRQIYAAGGGAVAKRPESNAWTVPTIGFPPPPPPPPSPAPIQHFARPLHVWGHPTMDPSRVPVWPPRHLVPRGPAPPWVPPPPPSDPAFWHHPYMRGPAHVPTQGTPCMAMPMPAARFPAPPVPGVVPCPMYRPLTPPALASKNQQDAQLQLQVQPSSESIDAAIGDVLSKPWLPLPLGLKPPSVDSVMGELQRQGVANVPPACG
The following text describes a protein:
Function:
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
Subcellular Localization:
Secreted, extracellular space, surface film.
Sequence:
MKESKRTLALSMIILFLTAIIVVGATLIGVYMTQKHTEAVIQMALNDHNGEKVQQTVMVSDKENIALFYVKANNESSTILYDYKQEVIAFRQMTSEKCYIMNMSQANVPKLKDILYDIKRFQATNTTRLNNMNYNLLEEEEADNTKLGITVNILCSDATIYWATMSKSERLRWKITIPFKIFGFQGSITIEFF
The following text describes a protein:
Function:
Transcription factors AN6788 and AN6790 act in tandem to regulate the expression of the non-reducing polyketide synthase pkfA from the aspernidine A biosynthesis cluster. They do not control the expression of the other genes involved in aspernidine A biosynthesis, nor do they regulate the expression of the highly reducing polyketide synthase AN6791 and the esterase AN6793 with which they are predicted to form a secondary metabolite biosynthesis cluster (Probable).
Subcellular Localization:
Nucleus.
Sequence:
MDGRGPYGLACQNCAKGKVKCIAMPDGDGCQRCHRLKKPCHPSHGVRKRESQHFQSPLIEEMDAKLDSVLSLLQSVYLQPSSPNGQAQQYKRKASTPELSSPTQPARTSVSESTYILPPGPLTSPDIVDAEGALNRFREEVLRFCPFLYLPPGLTARQLQQERPFLFETILSVMTRSVQEKMNWSKRIKSTIAHSMVMENESNIDLLLGLLVYACWSQDHYLKRMPTLTRIVELAVSVVMDLNLNKPPPPDAHRLTELGGGNDPNWTRKGPKIRTAEEKRAVLGCFFVSSIISSYFYQMDAMRWTLQMEEDLGSLAASPEWPGDAALAVHVRLQLLAENARKLRDEHGTKPVHIPFFLKSFRFELEAIRNSIPPDLQKDDTILSQLHYVELSIHETAFTANVIPHSINTNNPIGPDAVDCMWHSLLAIKSWDTIYRRMPPDDHTRWSIIQWIHLSRAVVTLYRLSTHPAPDWNRDAVYKTLNIVDVFTHIRASFDQLVPNPGGPFPNDFWAHGWLLGRAIATWLHAPGRLHPPNTDEPTAWAQTSSSHNGEQVLPTWNPPAPALQPQPIQESLQFTNPAWMDGLGLPPGDPTGGMHQAAGLHPTGQMHF
The following text describes a protein:
Function:
Essential for the initiation of pectoral fin bud formation. Potentially acts downstream of retinoic acid and Wnt signaling and is required for tbx5 expression in the lateral plate mesoderm of presumptive pectoral fin bud regions.
Subcellular Localization:
Endoplasmic reticulum. Secreted. Golgi apparatus.
Sequence:
MGTMASPLFILIACLLSMRVGGAFFAGPLYPEMSNGTFHHYFVPDGYYEENDDPEKCQMLFKMMDNRKCTLDEDQDSVIRDDFTIIKRHIEDAARVLEGIGKSISFDLDGEDSYGKYLRRETTQISEAFSNSEKSLLELEVKFKQSQENELKEEHKISDDFLNMIVHTRDVLKETLDISLGLKDKHELLSLIIRSHGTRLSRLKNDYMKV
The following text describes a protein:
Function:
Dephosphorylates the Ser/Thr receptor-like kinase RLK5. May function as a signaling component in a pathway involving RLK5. Binds and dephosphorylates CLAVATA1 (CLV1). Functions as a negative regulator of the CLV1 signaling in plant development. Dephosphorylates SERK1 receptor kinase on threonine residues in the A-loop. Dephosphorylation of SERK1 controls SERK1 internalization. Component of a signaling pathway which mediates adaptation to NaCl stress. Is not a component of the SALT OVERLY SENSITIVE (SOS) pathway.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MAMIGMNIIGLFMVLMLLLISLIILFACKPWRYFSRFRSSSRFSSTFKVGDLQRPLISDDGNLIQGQTSEVTREYDLEGACYQNDGLLHSSLTEGRFYKQRLPSSSPHFSQGESFVLEVISEPSDNALVGQTLKLPAEKGSLAEVQTYDWQNNRNENLQYNLEKDRLINLSPRLVEDQRSWLFLEVIAGPAIGLQHAVNSTSSSKLPVKLGRVSPSDLALKDSEVSGKHAQITWNSTKFKWELVDMGSLNGTLVNSHSISHPDLGSRKWGNPVELASDDIITLGTTTKVYVRISSQNEFQIPFKIGVASDPMAMRRGGRKLPMEDVCHYKWPLPGANKFGLFCVCDGHGGSGAAQSAIKIIPEVLANILSDSLRKEKVLSKRDASDVLRDMFAKTEARLEEHQYEGCTATVLLVWKDNEENFFAQCANLGDSACVIHLGGRYIQMTEDHRVVSLSERKRFQEAGLALRDGETRLFGINLARMLGDKFPKQQDSRFSAEPYISEPLRIDQSSKDVFAVLASDGLWDVVSPKKAVQLVLQMRDKERGRESSAEKIANGLLNEARAMRTKDNTSIIYLDFDTSL
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere. Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MTAPFSIAALQEDLAAAKAHFDKWAIARLNALEDAKVEHVDLMREADGRVQDLSEEEEKLNETAAALQKLLEEQRVSLEHYQKELADIREEEASLPPRLADLEDTVSKEKQEIDKEIIELEDEGAVKESKAEALLLGDELYRKHLGLRFEHTPRDLLRLVFTQIDPRDTKREFSCQLHVTSTYTVLDCSPQVSGIEELQTMVNETNDFSLFVRLLRRKFKELVST
The following text describes a protein:
Function:
Has aldolase activity with fructose 1,6-bisphosphate. May play a role in the biosynthesis of aromatic amino acids (AroAA).
Sequence:
MRPFEDSPISRDGKVLILAYDHGLEHGPVDFEAVPATKDPEAVWDVATHDAVSAMAAQKGIAEAYYPSYSDDVNLLAKLNGTSNLWMGEPDSAVNWTVDYAADVGADAVGFTLYGGSNSEVEMAEEFRDAQEAARDHDLPVVMWSYPRGQGLKNDKNPDTIAYAARQALELGADIAKVKYPGSTDAMSHAVDMAGPTNVVMSGGSKTSDRDFLESVKGAIDAGASGLAVGRNVWQREHPAAFLDGLEAVVYEEASVDEALGRI
The following text describes a protein:
Function:
Component of the cell wall.
Miscellaneous:
MISCELLANEOUS: Present with 1590000 molecules/cell in log phase SD medium.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP) found in young daughter cells.
Sequence:
MQFSTVASVAFVALANFVAAESAAAISQITDGQIQATTTATTEATTTAAPSSTVETVSPSSTETISQQTENGAAKAAVGMGAGALAAAAMLL
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MNEGEVMDLDVPEGDLTEFAAGGEDELVAQQVMEAMWGNLMPVEGGVALLAQDEDGGGEEEGAPAPNAWQMVVGGQVLAPGPTPFLGQAEGEVGPPERIAESEDEEGGDWEMEEVEDDDAVSEFEDLLESFLEAETDHGPGLASDDDDEPSNDSGSPDDHDMPTAAPAAERIAQTNGTAPPEASTAEDSSGGTEPRPSAPPPDVAGPSNPSPGEERGRDQAIEEQLRQFLAAEAAAEVAPGGSALLPGEGGEERGRVEGPVGEAGVDAALEEAAAAAFQRQLLAAHGAMFPAGPGAAARRAGGDGGQPDYAALQRVIEGALRDAEVQSGTGAGEGSAAAPARLSASEEGIPQFEQAEGSLQALSHALFGRPDDRSNEPGQTTDAGSGAAPEQELEWLRAAAGDDATVAGPSDDVMRGLYTKYVTYHRIAAEAQPAAEAEAEDGVGLHFRACGHAIHAKCLEGYFQSLYQSSMQRELFEGAHIVSLDAGEFLCPVCRRLANAALPMLPAAPSNALLTSAPSAVPASSPAGASAVGEVPPGAENGATSSPVATPGPSPGGASAAGEVPPRAQNGASSSTGPPAVSESPRDAPDTGPSSQAEARPGETGAGMPIAEYVRPAVKLILDAEVRTDPNGPYGIDESYWASGRNQAPVAPEVTGALENLATRGARLSGRTRPTHGLELWEALGFTVQATELAARRVSGSPERGAGILDKLGRSTSDVGAEGAVPDKGKRAVTDTGASVPKEESSQVERAQSDVTDHVSKRLEALAAAAGDEGRSVLRPLAQATIALRGASIPEQLFRARGLQILAGALLRGKSRDELPSELTAGHSDRTAAETRFWRLLADPVLFHDPFSTLVRLLYVLKGDLLDAEGMKALIRFLHLVLLEACNSCPHAPSNQEASVPPTEATRAERLRRMSLPFLRQSALLLEALHPGSVPSFRSPAESAAAAAARSAASRTRIVAPPEEAADVIEAGAGHLEALVLEADLGLALERITAAERADVAAPADTWQRHFEAEVEGWRGVETYRGERDARPFQLMQLPRNYHELFQRYVKAKCRLCKTVPVQPVLCLVCGAFLCGHSRKACCRVDNRGECYRHASECGVGVGVFLFLRRTTITLLRNGRQTVWLSPYLDAHGEEDIDLRRGKPLFLSEERYNALTEMVASMGMDHDSQVLARTVRRLPQAIE
The following text describes a protein:
Function:
Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Mediates the efflux of glycerol, formed upon triglyceride hydrolysis, to avoid its accumulation in adipocytes and to make it available to other tissues. In the kidney, mediates the reabsorption of glycerol, preventing its loss in urine, again participating to energy homeostasis. In pancreatic beta cells, it also mediates the efflux of glycerol, regulating its intracellular levels (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Lipid droplet. Note=Internalized from the cell membrane in response to catecholamine-induced activation of PKA; detected on intracellular membranes and colocalizes with lipid droplets (By similarity). Colocalizes with PLIN1 in adipocytes, probably on lipid droplets.
Domain:
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro/Ala-Ala/Ser (NPA).
Sequence:
MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF
The following text describes a protein:
Function:
Tail protein that binds the portal ring and functions as a head completion protein. 12 copies of gp4 form a structural ring at the bottom of the portal ring. Together with gp10 and gp26, gp4 is required for stabilization of the condensed DNA within the capsid; perhaps by plugging the hole through which the DNA enters. Plays a role in ejection of the bacteriophage DNA into the host cell at the initiation of infection. Functions as an exolysin that catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycans.
Subcellular Localization:
Virion.
Domain:
The N-terminus changes its conformation when transitioning from the preassembly state to the postassembly state.
Sequence:
MQIKTKGDLVRAALRKLGVASDATLTDVEPQSMQDAVDDLEAMMAEWYQDGKGIITGYVFSDDENPPAEGDDHGLRSSAVSAVFHNLACRIAPDYALEATAKIIATAKYGKELLYKQTAISRAKRAPYPSRMPTGSGNSFANLNEWHYFPGEQNADSTTPHDEGNG
The following text describes a protein:
Function:
Mitochondrial GTPase involved in assembly of the large ribosomal subunit. Plays a role in expression of the mitochondrial translational machinery.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein.
Sequence:
MAAKFIPRQAFPSYASIPRSYYLGHHKAGLKKMQNMLSSIDYVIECRDYRVPITSINPMFEEALGKTRRLVVYTKRDLGAEPRSSAQRTAEKIIKKFDSSSAVFFVSSSSRADVSSILAHLRNDAEGPDKLVGCRVMVVGMPNVGKSTLINNLRNQGVKRAKAVQTGGQPGITRKIGTPVKIIERDNGAHVYVLDTPGVFMPYVPDAEKMLKLALCGCVKDSVISPVTLADYLLYHINLHNPGQYERWSQPTNEISPLLDSFARQTGLLAKGGIPNIDLAALHLIQKWRSGELGRFMLDDLQAEQRRIDEGIENDVGISISQALKAERMSRKQPASNS
The following text describes a protein:
Function:
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
Subcellular Localization:
Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis-Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface. Note=May be associated with receptors at the cell surface.
Sequence:
MAPLRDRVSTLPRLQLLVLLLLPLLLVPQPIAGHGGKYSREKNEPEMAAKRESGEEFRMEKLNQLWEKAKRLHLSPVRLAELHSDLKIQERDELNWKKLKVEGLDGDGEKEAKLVHNLNVILARYGLDGRKDTQTVHSNALNEDTQDELGDPRLEKLWHKAKTSGKFSSEELDKLWREFLHYKEKIHEYNVLLDTLSRAEEGYENLLSPSDMTHIKSDTLASKHSELKDRLRSINQGLDRLRKVSHQGYGPATEFEEPRVIDLWDLAQSANFTEKELESFREELKHFEAKIEKHNHYQKQLEISHQKLKHVESIGDPEHISRNKEKYVLLEEKTKELGYKVKKHLQDLSSRVSRARHNEL
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MDSSKQNLNQVIYSIDKTLEILHQLSSFDVNVASHLNNLVFEFDNMAKLGENCHSIKVPMEVLNLIDNGKNPDEFARDLLNNCIAKNQITKGKVDAFKDLRGHLLEDLEHAFPDEVEDYRQRRI