lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Transcription factor. Interacts, when in complex with WRKY71, specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Represses specifically gibberellic acid (GA)-induced promoters in aleurone cells, probably by interfering with GAM1.
Subcellular Localization:
Nucleus.
Sequence:
MMTMDLIGGYGRADEQVAIQEAAAAGLCGMEHLILQLSRTGTSESSPVGSSEAPEQQVDCREITDMTVSKFKKVISILNHRTGHARFRRGPVVAQSQGPAVSEPAPVRASSSRSMTLDFTKASSGYGNDAGFSVSAASSSFMSSVTGDGSVSNGRGGGSSLMLPPPPSASCGKPPLASSAASTGAGAGQKRKCHDHAHSENVAGGKYGASGGRCHCSKRRMNDGTGRKSRVRRMTRVPAISSKAAEIPADDFSWRKYGQKPIKGSPYPRGYYKCSTVRGCPARKHVERDPSDPSMLIVTYEGEHRHTPADQEPLAPLPEL
The following text describes a protein:
Function:
Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin-remodeling complex.
Miscellaneous:
MISCELLANEOUS: Present with 2300 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MKFEDLLATNKQVQFAHAATQHYKSVKTPDFLEKDPHHKKFHNADGLNQQGSSTPSTATDANAASTASTHTNTTTFKRHIVAVDDISKMNYEMIKNSPGNVITNANQDEIDISTLKTRLYKDNLYAMNDNFLQAVNDQIVTLNAAEQDQETEDPDLSDDEKIDILTKIQENLLEEYQKLSQKERKWFILKELLLDANVELDLFSNRGRKASHPIAFGAVAIPTNVNANSLAFNRTKRRKINKNGLLENIL
The following text describes a protein:
Function:
Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Membrane; Multi-pass membrane protein.
Sequence:
MAARSRQRSSAPLQVLLFLNGWYSATYFLLEAFIFAYKVLLLPYPLTNLLLDVLLLLLYLGIEATRIFFGSKGNLCQRKVPLAVCLALTVPAAVMATYCLLLQTYALRLEAILSAILLLFYSVELLLGGLALASFSRVRYKGGVHPWRRSRPGWMWLWAAWAGGW
The following text describes a protein:
Function:
In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.
Subcellular Localization:
Dynein axonemal particle.
Sequence:
MTSKNEQDLIGYNQFPCLFHTSMWGSILASVKEQLPSFESDSSSSDSEDGELFIFQRDEENLIPDLTEELADDPDIQFLESVTNTEKNWNERIKDSAIFEGKDASEFLVVRPAFEDTEEISSGSHLKVPKESTKWQKGDTWDFFRSRVQALIRGSQVEEFPTLTCPTGLLTDNLRICNFSPSEESDSTSIKVIRKERRKMIEKNILHKEIKMSPLENLNRRQFIKPEIHESSESVGIEEKMPAKHEGLTLQYLEKLEEWDLDKILQNLEAQKGQGKRKTGATYWKVPSSFKGRGSLTSNSQEKLMEQLVALCAKQSQNTLPIPREKPSDKLLYPMEDQIQSRSSWCRSPLTPGQSQDMAKDTKLKWPVEPPTVFIDLRQPEPKKSVLLPLSDYRFQNQEDELSSSDSSTENEEETPDVRDEKGSRKRMSQRKRDQTGKSYLLQQLRAFQRETAEARGPETKVTAQQGHGAQNPETSEDVAMLGIGKKQPKTSLGGSKRLPLPDPKAKQRGEKQKGTSRSSDSESFVKDPVTPLIKKREISSSWKK
The following text describes a protein:
Function:
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
Sequence:
MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL
The following text describes a protein:
Function:
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).
Subcellular Localization:
Nucleus.
Sequence:
MKLGEFVEETKNHSPNYITSSMFAKLHHAQNFHHQLPPQPISTVAAPPSSSANDGATIEVVRRPRGRPPGSKNKPKHATFIIKTRDDHVEKPSMSPYILEIPTEVDIIDSIFRFCKKQNMGLCVLNGSGTVTNVTLKQPSNSTAASTVTFQGAFNILSISATIVLENSSLPNGFTISLAGPQGQVVGGAVIGPLLSAGTVYLIAATFNNPCYHKFPVEDEDGGQSPPVAVSGGGDSGHPPDQSFCTSNQLPSDMIWAPTARQPPPPY
The following text describes a protein:
Function:
Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation. Required for NSL complex stability and for transcription of intraciliary transport genes in both ciliated and non-ciliated cells by regulating histone H4 acetylation at 'Lys-5'- and 'Lys-12' (H4K5ac and H4K12ac). This is necessary for cilium assembly in ciliated cells and for organization of the microtubule cytoskeleton in non-ciliated cells. Required within the NSL complex to maintain nuclear architecture stability by promoting KAT8-mediated acetylation of lamin LMNA.
Subcellular Localization:
Mitochondrion. Nucleus.
Sequence:
MADQPRMQFPEKQLKTNHAPSTTAEKDVAALKAELEIELKNKKQCTYKPYECTQLTLDGFNYCLKHILQDKAAPYRQCSYIYASNGKRCQLAAPKIEKKDCGYCNDHAVKVTLEKNRQNSRLQPPQTAEVLIYSLGHYLKKPRNRATSGSGEEAERALLEEAEAKSTKCLDPFRDIDANALYNSTCNNVLDFCSESDSDVEASTFASVWHDAQNDSSDNESVDSDQEDVLKHANVYTAEEISSITREKLIKLQSLYIEQYRHLQHVFKECKRKYVYNLRREKETCCNIYNQIRENPKEQRLYKKLKALNKYHKPHGVEAILHKREHDSRAKITDGMFSKAPGYSRCLFTEGGVKCGERTLPLARHCRKHILEDQNQVLFRPCGKKRADVECKTPVEAIFEDSCCNLHMDIPPIKSYAQLRKNSESDFEDSFESPENMLMEAVSESDNVKTEFIDYGPNLEEMKTLPSVLFEESSMDASIKNEDTENEKPDEDVQIDVDDEPSPEGKLEIDIPEEDTNDIRIEDKMEEDSSQDKPAPEPPVTDN
The following text describes a protein:
Function:
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
Subcellular Localization:
Glycosome.
Sequence:
METRHHLNTKMVPSYQAPLSKVTAADLTVERLPGCKYMNPSKKHILRKEYRDKVEHIMYDPRPQEDLDAEYPVSCNKLVCELAAARKHLHFNPSETSIGIVTCGGICPGLNDVIRSITLTGIISYRVKRVVGFRYGYWGLSKEGSKTAIELSRTDVRQIHRFGGTILGSSRGPQSPKEMVDTLVRMKINILFTVGGDGTQRGALTIYEEAKRRGENIAVFGVPKTIDNDLAFSHRTFGFQTAVEQAVNAVRAAYAEAVSLNYGVGIVKLMGRESGFIAAQTTVASAQANICLIPENPLPKETVMRLIERRLQQSRNCVIVVAEGFGQDWETGTGGHDASGNKKLVDIGFILKKEVEGWLRANKEKFPQGTVKYIDPSYMIRACPPSSNDALFCTNLATLAVHEAMAGATGCIISMRYNNYILVPIKAATSVRRVVSLRGALWRQVREITVGLSDDVQQWNEQDLRRHLESLNVERERIIARLASKV
The following text describes a protein:
Function:
Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst (Probable). They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk (Probable). Involved in formation of the ventral disk.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Microribbons of ventral disk. Localizes to adhesive disk in trophozoites. Localizes to median body of the trophozoites, especially at G2 phase of the cell cycle. Localizes mainly to the trail structure of the adhesive disk in encysting cells.
Sequence:
MKSSFSTVSSYSDHKFAVKDAPTTIRDSLRLTNAVEDPGYMTLSLISENKVDDLMFNSKMFQDHMVNDFRPKFSHADSSEIMITLNNLKNDILSTKNIRELESTDLRSEVAKQFAARRAELVSHLNASLRPLIDEVFSMEQRLKAFDAENADFVGKTKQYKSTFRSEVHSRIRAGQSKLDALRHGLQTEINSLEAIIEREFAQAANRLNQEVSNFKESFDASERNIKLQKKHVISGMNEKIKSFAESVAKYLPILKKNSEERRFNQMMMQKNLAEIMTVLSDNSEHFGDYCFSDLVPDTRIFDAIMTTKVD
The following text describes a protein:
Function:
Binds the phosphorylated C-terminal domain (CTD) of the largest subunit of RNA polymerase II and functions as a scaffold for RNA processing machineries. May be involved in pre-mRNA splicing (Probable).
Subcellular Localization:
Nucleus.
Sequence:
MANNHQYPGIQPFQHPNASSIDLPRGFAPPMNFQFLPTIQAPQSEQVARLSSQNFQCVGRGGTVLSIGYPPQSYAPQLLQSMHHSHERPSQLNQVQVQHVPLGPPTLISQPNVSIASGTSLHQPYVQTPDIGMPGFGGPRALFSYPSATSYEGSRVPPQVTGPSIHSQAQQRASIIHTSAESSIMNPTFEQPKAAFLKPLPSQKALTDWVEHTSADGRKYFFNKRTKKSTWEKPVELMTLFERADARTDWKEHSSPDGRKYYYNKITKQSTWTMPEEMKIVREQAEIASVQGPHAEGIIDASEVLTRSDTASTAAPTGLPSQTSTSEGVEKLTLTSDLKQPASVPGSSSPVENVDRVQMSADETSQLCDTSETDGLSVPVTETSAATLVEKDEISVGNSGDSDDMSTKNANQGSGSGPKESQKPMVESEKVESQTEEKQIHQESFSFNNKLEAVDVFKSLLKSAKVGSDWTWEQAMREIINDKRYGALRTLGERKQAFNEFLLQTKRAAEEERLARQKKLYEDFKRMLEECVELTPSTRWSKTVTMFEDDERFKALEREKDRRNIFEDHVSELKEKGRVKALEDRKRNIIEYKRFLESCNFIKPNSQWRKVQDRLEVDERCSRLEKIDQLEIFQEYLRDLEREEEEKKKIQKEELKKVERKHRDEFHGLLDEHIATGELTAKTIWRDYLMKVKDLPVYSAIASNSSGATPKDLFEDAVEDLKKRDHELKSQIKDVLKLRKVNLSAGSTFDEFKVSISEDIGFPLIPDVRLKLVFDDLLERAKEKEEKEARKQTRQTEKLVDMLRSFKDITASSSWEELKHLVEGSEKCSTIGDESFRKRCFEDYVSLLKEQSNRIKQNKKVPEDVREEHDKGRDKYGREKDRVRERDSDDHHKKGAAGKYNHDMNEPHGKERRRSGRDSHNRHRERHTSVKENDTDHFKESHKAGGGHKKSRHQRGWVSEAEVEGKEKRRRKEEAREHTKEEELEDGECGRY
The following text describes a protein:
Function:
Unknown. Non essential.
Miscellaneous:
MISCELLANEOUS: Present with 15400 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPALLKRLLFQVGPHPNERTFTLSSVSTDGHYISLRPFVKPSGDELSFPFEWAFAGTNETVKANDQGNGVVTQDFNFWLDTNVYLNVPNTHRGEVNTTWKNWDSGCVEETGAVYPFGADKESVSFRELWQPVDPSREDLVIVSPNNEKFSSNARSIVLKVTDEAYDGLVIVIGRWIQGFLSQKNNNTIEGLNFIRLLEKDSGKSEFLLSYGKEVNKIPQSYENLKKGSTVTSNGLNWEVIEYHA
The following text describes a protein:
Function:
Inactive serine protease which plays an essential role in the innate immune response against bacteria, fungi and protozoa infection by activating the melanization cascade. In the melanization cascade, acts downstream of TEP1, SPCLIP1 and CLIPA8 to promote CLIPC9 proteolytic cleavage. In the susceptible strain G3, appears to be dispensable for parasite P.berghei ookinete elimination which occurs by lysis. Required for the melanization of Gram-positive and Gram-negative bacteria. Required for the melanization of fungus B.bassiana.
Subcellular Localization:
Secreted. Note=Secreted into the hemolymph.
Sequence:
MKVLLFCIVISLTTLIASGQDIEEELRCPGGYCVSKYLCPNGTFIDDIKHAQTTQLIGLRAGLDIDDFDDCNDYLLVCCQSAPAPTATSTEKPATSDELIEPPPSTNLACGQANEGGLIYDLRNNETLSQYAEYPWVVYILALKKQEANSGDFVCGGTLIHSRLVVTTAHNTDGKTDLVARFGEWDISTTKEPFPQQDIDVAEVIKHPQYVFNPIQNDIALLVLAENVQYAAHIRPICLPQPTDEFVGQRCVSNGWGKERGVYANVMKKLTLPVIGRANCTRMLRYAGLGPFYTLREGFLCAGGEVAVDMCKGDGGSPLACQTESGTYVLAGIVSWGIGCGGFNTPGVYVAVNRYVQWLNEHIVDQALNESFDIKL
The following text describes a protein:
Function:
Can function as a Delta(12)/Delta(15) bifunctional desaturase and behaves as a nu +3' desaturase. Introduces a double bond in the fatty acid chain three carbons away from an existing double bond to biosynthesize polyunsaturated fatty acids (PUFAs) endogenously (PUFAs are essential for membrane structure and many cellular and physiological processes). Acts on a number of substrates like oleoyl-CoA ((9Z)-octadecenoyl-CoA, 18:1n-9), palmitoleoyl-CoA ((9Z)-hexadecenoyl-CoA, 16:1n-7), and gamma-linolenoyl-CoA ((6Z,9Z,12Z)-octadecatrienoyl-CoA, 18:3n-6), to generate linoleoyl-CoA ((9Z,12Z)-octadecadienoyl-CoA, 18:2n-6), (9Z,12Z)-hexadecadienoyl-CoA (16:2n-4) and (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA (18:4n-3) respectively. Unlike plants, Caenorhabditis elegans desaturases seem to use fatty acyl-CoAs as substrates (Probable).
Miscellaneous:
MISCELLANEOUS: HPO-19 and T05H4.4 are cytochrome b5 reductases required for PUFA desaturation in Caenorhabditis elegans. HPO-19 knockdown or mutation alters FAT-2 desaturase activity. Although FAT-2 lacks a cytochrome b5 domain, its N-terminal contains a DUF3474 domain that may possess some oxidoreductase activity for electron transfer, obviating the need for an extra cytochrome b5 enzyme, but still requiring cytochrome b5 reductase HPO-19/T05H4.4 to become activated.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTIATKVNTNKKDLDTIKVPELPSVAAVKAAIPEHCFVKDPLTSISYLIKDYVLLAGLYFAVPYIEHYLGWIGLLGWYWAMGIVGSALFCVGHDCGHGSFSDYEWLNDLCGHLAHAPILAPFWPWQKSHRQHHQYTSHVEKDKGHPWVTEEDYNNRTAIEKYFAVIPISGWLRWNPIYTIVGLPDGSHFWPWSRLFETTEDRVKCAVSGVACAICAYIAFVLCDYSVYTFVKYYYIPLLFQGLILVIITYLQHQNEDIEVYEADEWGFVRGQTQTIDRHWGFGLDNIMHNITNGHVAHHFFFTKIPHYHLLEATPAIKKALEPLKDTQYGYKREVNYNWFFKYLHYNVTLDYLTHKAKGVLQYRSGVEAAKAKKAQ
The following text describes a protein:
Function:
Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 (By similarity).
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MYWKKLLFAIASAAALAAVDPETEGSELQTICSGGECYPRLFKALQDWSTIKEGQQIPPGLDIRVDLSTGKKQARLPIPNEASNMENGIQVVDDSSDYEFTKEFQLVRAQVASGAPDYNVVIKQLDDLVEYASDYTLGYKIITHEFTLLQELIFGQDVPISVKELSSRIIVACLRNNTPCLDFVNTRFPDFVRHLLQEAVDYGRQATDAVEARTQIKRYLSIVEPLLINEPQPINEEALKQLYEVNDQTVQLKVLLIMARLYKGRSHNDDISKRSLESTDVQRWTTELSKAIQSKHLDDFHVRELFHGLYALKKEHGRAVKTYPTFLGWLAEETEARKQRMTQDKQPRDLEQMEFDRLLIESRHMVFGNPMAHRIKNMEYDEL
The following text describes a protein:
Function:
Required for peroxisome inheritance.
Subcellular Localization:
Endomembrane system; Peripheral membrane protein.
Sequence:
MFSIFMRIPDTAQVDAVFSGAYASIEQGLCYDEVNDWENTLAMYEKGLNLIVEGEKMKNARKSEMWKMLQESKSSVQHRINVLKKEGPKQPTPKKIKEAEESVENEKEAIRMQLDSFGSQEADLIYFLPEGVQLFTIDGEKTTAPTAPTSLQILRFPQPTDGGASSDTLAFMQVGPWAYPLMGAKTPVLRNEFGAYLVANPTPENPNMTVAILLSSDIERRLIEELHIVLREFTDFKEQAEPSTELSKEEKNRISTTISNFLIKGGQKIAWGVETTTVRVISRVEDNGEQYRTTLIATDKPMQVSPVIKGSVVYMHKGTKTVAKCTRYLLDKIGDMGVSMGKKLADSAQRRFGDGKSGGLVSGTIEILGGGITGVATVWMSLEDGSRHLCRSIANQTVQNVKLKYGDDASDTTHHALFAAGHGTLAAAQLWDLGPRSVAGRMARKAGIQMVSDLHHSRKGSRLDQEVPALELKKAV
The following text describes a protein:
Function:
Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.
Sequence:
MESLEPKAPTWTENDLLVLITEYWKRKEILRAKASESVTNLQKRECWIEITEVVNARCFSPHSKKTMDQLKRKWEKTIMLAKKAALSIQKRSGNLSDLAPAYQLALSIVCEDFPASLECQNGLAAADASSLTDHQHATYIDEVSSMVITELEEESSTDAPPPASEHKTRQPIRTEMLSEGAECPHPLGSRPFQPVLAVGPEDGAASAATLDAHSNHGAEADEDDRFDFPSKSGQKRKWDPDLIELQREKVRRQIQYHRTQHELQMSVLRAQMDFWDMKKAKLAAEIRQMAPARSPAPAVTPDDPS
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Mitochondrion.
Sequence:
MGSPSLTKTINASLSLHSITQPITLLKTMHYVLQLTILPSAMQHYATLRNFTHPACSVNKQAEQGKEQQQYAMKSQFQFRSGICSKVRSDELGFKGNSLQLNDLPKNPY
The following text describes a protein:
Function:
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation.
Subcellular Localization:
Cell junction, focal adhesion. Cell projection, filopodium. Cell projection, lamellipodium. Cytoplasm, cytoskeleton. Synapse.
Sequence:
MSEQSICQARAAVMVYDDANKKWIPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQESGPTLSRQNSHIPTQVQNGPSQEELEIQRRQLQEQQRQKELERERQERERLERERLECERMERERLERERLERERSERERLERERLEQERLEQEQLELELQERERQEQLEQELQEQERLEQERQEREAQEQLEKEQLEWERERRVSNADSSFDNSLYNTQHVDFSTCLPHAPSPITYAKAISVPVSSICTESIADYVLVTSTSINSTPPTPPLRHSASRFATSLGSAFHPVQPHYATVPRPVNKIARPPSPVNAAPPPPPPPPVKPLSWSASNFAPLPPSPPVMISSPPGKATGPRPVHLVSAHNQLAQMVHMSCAPSGHTDSSIYQVSSTPAANPFPPPPPPLPSFLPFSLSSSPSPSTSVVSAPSSQPSVLPSPSAASPASVENSLCSVLGDFSASQPDLTTPSQLIDPAAHPGVIPGPPTPPPPPPLPPGSSLSSATTPPAPPLPPPLPPSGPAPPPPPGPPPPPGPPPPLHSQAPPLAPPPPPAPPLPSSAASFGSEENHPLSGLAAALAGAKLRKVSRNEDSATQGVASATGTSSAAAKTEPSRGNGPLPMGGGGLMEEMSALLARRRRIVEKAPTVEADPKEDKAEESEPLPTKAPSASTPEPTRKPWERTNTINGSKSPVISRPKSTPSGQPSANGVQSEALDYDRLKQDILEEMRKELTKLKDELIDAIRQELGKSNSA
The following text describes a protein:
Function:
Cytochrome P450 involved in the biosynthesis of the phytoalexin glyceollin. Stereospecific for (6aR,11aR)-3,9-dihydroxypterocarpan.
Subcellular Localization:
Membrane.
Sequence:
MAYQVLLICLVSTIVFAYILWRKQSKKNLPPSPKALPIIGHLHLVSPIPHQDFYKLSTRHGPIMQLFLGSVPCVVASTAEAAKEFLKTHEINFSNRPGQNVAVKGLAYDSQDFLFAFAPFGPYWKFMKKLCMSELLSGRMMDQFLPVRQQETKRFISRVFRKGVAGEAVDFGDELMTLSNNIVSRMTLSQKTSENDNQAEEMKKLVSNIAELMGKFNVSDFIWYLKPFDLQGFNRKIKETRDRFDVVVDGIIKQRQEERRKNKETGTAKQFKDMLDVLLDMHEDENAEIKLDKKNIKAFIMDIFVAGTDTSAVSIEWAMAELINNPDVLEKARQEIDAVVGKSRMVEESDIANLPYLQAIVRETLRLHPGGPLVVRESSKSAVVCGYDIPAKTRLFVNVWAIGRDPNHWEKPFEFRPERFIRDGQNQLDVRGQHYHFIPFGSGRRTCPGASLAWQVVPVNLAIIIQCFQWKLVGGNGKVDMEEKSGITLPRANPIICVPVPRINPFPTI
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Sequence:
MSRPVIHYFPIRGRAEVLRLAIVAGGDDFDVVDVNYQEQKSDREKYPFGQCPRLVDGDLNIVQSNTIARYLARKYKLQGKDETEMVAVDEIMEGVESLRVKYVNLIYNDKLEEAAKDLYWKTYFDKTTSEGRNGGAHMVYLANFLAKNGGKHTVGAGLTIADLCLWEILDLHLRIFEDAIKKEYPELVVFHDHIASQPGIKEYLASPKRLAAPNANTLG
The following text describes a protein:
Function:
Binds to F-actin. May be involved in regulation of the actin cytoskeleton.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MTGSLFKGNFWSTDILSTVGYDSIIQHLNNGRKNCKEFEEFLKERASIEEKYGKDLLNLSRKKPCGQSEINTLKRALDVFKQQVDNVAQCHIQLAQTLREEARKMEEFREKQKLQRKKTETIMDAAHKQRNSQFKKAMDAKKNYEQKCRDKDEAEQAVHRSANMANQRQQEKLFVKLATSKTAVEDSDKAYMLHINMLEKVREDWQSEHIKACEVFEAQECERINFFRNALWLHVNQLSQQCVTNDEMYEQVRKSLETCSIEKDIQYFVNQRKTGQVPPAPIMYENFYSPQRNAAPPAKTAGPHPAR
The following text describes a protein:
Function:
Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.
Subcellular Localization:
Nucleus. Note=Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it accumulates on chromatin.
Sequence:
MDANSKDKPPETKESAMNNAGNASFILGTGKIVTPQKHAELPPNPCTPDTFKSPLNFSTVTVEQLGITPESFVRNSAGKSSSYLKKCRRRSAVGARGSPETNHLIRFIARQQNIKNARKSPLAQDSPSQGSPALYRNVNTLRERISAFQSAFHSIKENEKMTGCLEFSEAGKESEMTDLTRKEGLSACQQSGFPAVLSSKRRRISYQRDSDENLTDAEGKVIGLQIFNIDTDRACAVETSVDLSEISSKLGSTQSGFLVEESLPLSELTETSNALKVADCVVGKGSSDAVSPDTFTAEVSSDAVPDVRSPATPACRRDLPTPKTFVLRSVLKKPSVKMCLESLQEHCNNLYDDDGTHPSLISNLPNCCKEKEAEDEENFEAPAFLNMRKRKRVTFGEDLSPEVFDESLPANTPLRKGGTPVCKKDFSGLSSLLLEQSPVPEPLPQPDFDDKGENLENIEPLQVSFAVLSSPNKSSISETLSGTDTFSSSNNHEKISSPKVGRITRTSNRRNQLVSVVEESVCNLLNTEVQPCKEKKINRRKSQETKCTKRALPKKSQVLKSCRKKKGKGKKSVQKSLYGERDIASKKPLLSPIPELPEVPEMTPSIPSIRRLGSGYFSSNGKLEEVKTPKNPVKRKDLLRHDPDLHMHQGYDKYDVSEFCSYIKSSSSLGNATSDEDPNTNIMNINENKNIPKAKNKSESENEPKAGTDSPVSCASVTEERVASDSPKPALTLQQGQEFSAGGQNAENLCQFFKISPDLNIKCERKDDFLGAAEGKLQCNRLMPNSQKDCHCLGDVLIENTKESKSQSEDLGRKPMESSSVVSCRDRKDRRRSMCYSDGRSLHLEKNGNHTPSSSVGSSVEISLENSELFKDLSDAIEQTFQRRNSETKVRRSTRLQKDLENEGLVWISLPLPSTSQKAKRRTICTFDSSGFESMSPIKETVSSRQKPQMAPPVSDPENSQGPAAGSSDEPGKRRKSFCISTLANTKATSQFKGYRRRSSLNGKGESSLTALERIEHNGERKQ
The following text describes a protein:
Function:
GTP hydrolase that promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Subcellular Localization:
Mitochondrion.
Sequence:
GPLRVRTSKMALPAALLRAAALRCRLPLASVGRRHLAAEAFVRDRPHVNVGTIGHVDHGKTTLTAAITKVLSESGGARFQRYEDIDKAPEERARGITINAAHVEYSTARRHYAHTDCPGHADYVKNMITGTAPLDGCILVVAATDGQMPQTREHLLLARQVGVRHVVVYVNKADAVSDAELLPLVELELRELLAEMGYDAERTPVVVGSALCALQDRDPTLGRDSVLQLLEAIDTHIPLPHRDVQRPFLLPIEGVHSIPGRGTVVTGTVERGAVSKGDECELRGYGRVLKAVVTGLETFHKSLPRAEAGDNVGALLRGLRREDVRRGMVMGQPGALRDHRKLQAQVYVLSAQ
The following text describes a protein:
Function:
May have a role in cell division.
Sequence:
MWAYHFPSVPPLISFSPSAAAAVHNQSAMAQEQLVLRGTMRAHTDWVTAIATPIDNSDMIVTASRDKSIILWSLTKEDRTYGVARRRLTGHSHFVEDVVLSSDGQFALSGSWDGELRLWDLQTGNTARRFVGHTKDVLSVAFSIDNRQIVSASRDKTIKLWNTLGECKYTIQDQDAHSDWVSCVRFSPNTLQPTIVSASWDKTVKIWNLTNCKLRSTLAGHSGYVNTSAVSPDGSLCASGGKDGVILLWDLAEGKRLYSLDAGSIINALCFSPNRYWLCAATEASIKIWDLESKSVVVDLKVDLKHESEIAPEGATQSAAAKNKVIYCTSLSWSADGSTLFSGYTDGVVRVWGIGRY
The following text describes a protein:
Function:
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
Sequence:
MGLNITGLIPKHMENRGKLTLKENLKIIENILEQRKAPENGIDEEHIKLLLRLLSFMDTDKDPNVVQIGEREARVYTKLQRDGVFDFCHGVGRSGNLIDPQPKAPGASVMYKLTNKLLESFLKALGLKVNAIATPVATGMSLALCLSAARKKYNSNVVIYPYAAHKSPIKATSFIGMRMRLVETVLDGDIVKVEVSDIEDAIRKEINENNNPVVLSTLTFFPPRKSDDIKEIAKICQDYDIPHIINGAYAIQNFYYIEKLKKALKYRIDAVVSSSDKNLFTPIGGGIIYTKDESFLKEISLTYPGRASANPIVNILISLLAIGTKDYLNLMKEQKECKKLLNELLEDLAKKKGEKVLNVENPISSCITTKKDPLDVAGKLYNLRVTGPRGVRRNDKFGTCYLKEYPYDYIVVNSAIGVKKEDIYKVIEKLDEVL
The following text describes a protein:
Function:
Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the centriole lumen.
Sequence:
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVVPSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLREDSEDNIHKFAEATLPVSKIPKYPTNPPGQLPSPPHVPSYWHPSRRIQGSLRDPEFQHNVGKARMNNLQLPQHEAFNDEDEDRLSEISARSAASSLRAFQTLARAKKRKENFWGKT
The following text describes a protein:
Function:
Probable DNA motor protein. May track DNA in a ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind it (By similarity).
Miscellaneous:
MISCELLANEOUS: Although strongly related to FtsK, it lacks the typical transmembrane domains located at the N-terminal part of FtsK.
Sequence:
MRRLQREIRTYDEEQLKQVREELTTYDLMTRNALLQTAHDLRAKVEQEAVPEGEQATTYLKAVVDDRRHELSVFLPATQASAALENVRRHLVNQILSIGGKAKKLETERCAAERHLKRPTVEVVQREHDAHLRRLRQWQEVQSRFQTWHTYEQAYARWPDLAAAFDSGPTEAATRVATELHKRTLATMQEQDRWREFLRQATEQEHQRQLTPPEDDLPEDDLEEDTWAAAESSEPSGSLFSRLGHTLSRLMAPPGPDEVPSAATAPRETDGWDDVQPQIAPDPRSTVPGLWDDADDLTPVSPVAPARPAPSPPVYDAAAVPALDIDFSAAPRRSRTPAEQMPDPFARAARVRSARRTTTPLVPVPQQLDAAEMPAPRPARTPPGRPATAGNVAPPSAPRTARPPSPTLADFDLWDDEEDMPFGPPATPAPAAASVPQMVPTPRAAARPTPRPVSSPGPSPVPVSPASASVSHAAPWEEPAAGRPAPAPSGVSRRGATRLALPSEQLLDPLPNGARNTVQMDLDAERRGDMINETLRQFGLQAKVVDLARGPTVTRYEIEPAPGEKISRIASLSNDLARALAVGGVRVEAPVPGKSVIGLEVPNAEREPVTFHQATANPAFKNTRAKLPIILGKSIDGSMMVGDLAKMPHLLVAGSTGSGKSVCVNTLITSLLYRYLPTELRFVMIDPKMVELTPYDGIPHLVRPVVTNPADAAGVLLGAVAHMERRYKMMSQVGAKNLEQFNAKMRAVGEVELPHLVIIIDELADLMITSPKEVESAIMRLAQMARATGMHLILATQRPSVDILTSLIKVNIPARIAFAVSSSHDSRTILDTTGAERLTGMGDMLFYQPGLVKPLRLQGPYISEAESARITDELRRMMFDDDFIEAYGADFEGMISSSGPGGDRSQLDFSDPLLRQAALVCIEEGQGSVSRLQRRLSVGHARAGKLMDLLEAMNIVGPHQGSKPREVLIHEADLPEYFGK
The following text describes a protein:
Function:
Involved in ribosomal large subunit assembly.
Subcellular Localization:
Nucleus.
Sequence:
MSVHVEKELPLELDLGNMCAFDIAPVSKGIKEEQLRALARDNAQVLINQMFSLPTESTKDGLLLLLPDGTTPLPRAKPLPKPKPETRWQKFARIKGIAPKKREGKLVYDEASGEWVPRWGYGGKNKALDNQWLVEEGEKEAHEKIQKLKKQGKKIKRSRRH
The following text describes a protein:
Function:
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity).
Subcellular Localization:
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Domain:
The N-terminal and the C-terminal halves of the protein can associate with each other, thereby hindering interactions with ZYX.
Sequence:
MDLAVKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARHYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKLPREMDAQGPPRIDSPGGDRSTAAAVGAMDGKSAEHRRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCEELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVDDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNGFSWHAAAECFLCSCCSKCLLGQKFMPVEGMVFCSVECKKMMS