lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation. May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MGKRQHQKDKMYITCAEYTHFYGGKKPDLPQTNFRRLPFDHCSLSLQPFVYPVCTPDGIVFDLLNIVPWLKKYGTNPSNGEKLDGRSLIKLNFSKNSEGKYHCPVLFTVFTNNTHIVAVRTTGNVYAYEAVEQLNIKAKNFRDLLTDEPFSRQDIITLQDPTNLDKFNVSNFYHVKNNMKIIDPDEEKAKQDPSYYLKNTNAETRETLQELYKEFKGDEILAATMKAPEKKKVDKLNAAHYSTGKVSASFTSTAMVPETTHEAAAIDEDVLRYQFVKKKGYVRLHTNKGDLNLELHCDLTPKTCENFIRLCKKHYYDGTIFHRSIRNFVIQGGDPTGTGTGGESYWGKPFKDEFRPNLSHTGRGILSMANSGPNSNRSQFFITFRSCAYLDKKHTIFGRVVGGFDVLTAMENVESDPKTDRPKEEIRIDATTVFVDPYEEADAQIAQERKTQLKVAPETKVKSSQPQAGSQGPQTFRQGVGKYINPAATEQQRKSPQPVPLSPCPRRSPVGVLGTSAPGSSSNLQAVPLPFLFSSITDAEAAGLSPLSPWMLGGASSASLPHPIHCHRLPDDH
The following text describes a protein:
Function:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules.
Sequence:
MASGDFCAPGEGVEMLLQVCGKQFPPCALTEEDLIQNPRFSKLLLSLSQHVDESGLSLTLAKEQAQAWSEVRHRKTAWLRYEILQRVIQELLVDYYVKAQDTNLTSEDKKFHETLEQRLLVTELTQLSGPGQETELPPLLGLERTDLLELMPPSQDFVWMKARLQLEVEEQLKRKCFTLLCYHDPSSDTDGDTLKAAKVWTLTEVLVREKQQCLEAKSQQKEQLVLLEKKRTTYSQVLLRCLALLQRLLQEHRLQTKSELDRINAQYLELKCSAMILRLRMEELKVLSDTYSAEKVEMHRLIRDRLEGAIRLQEQDLEKSRLVLHTYEALGEDFESLVREYTQLRLAADNKRWALQELSKAQR
The following text describes a protein:
Function:
Component of the yop secretion machinery.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIADLIQRPLLTYTLLLPRFMACFVILPVLSKQLLGGVLLRNGIVCSLALYVYPAVANQPYIEVDAFTLMLLIGKEIILGLLIGFVATIPFWALESAGFIVDNQRGAAMASLLNPGLDSQTSPTGLLLTQTLITIFFSGGAFLSLLSALFHSYVNWPVASFFPAVSEQWVDFFYNQFSQILLIAAVLAAPLLIAMFLAEFGLALISRFAPSLNVFVLAMPIKSAIASLLLVIYCMQMMSHASKAMLLVMDPISLLIPVLEK
The following text describes a protein:
Function:
The main replicative DNA helicase, it participates in initiation and elongation during chromosome replication. Travels ahead of the DNA replisome, separating dsDNA into templates for DNA synthesis. A processive ATP-dependent 5'-3' DNA helicase it has DNA-dependent ATPase activity.
Sequence:
MDRMYEQNQMPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSTEGTLNEAGGPQYLAELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFKDIRDVLGQVYETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMYTVGIFSLEMGADQLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQGSGSRASDNRQQEVSEISRTLKALARELKCPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRGGDEDDDDDGGFEPQTNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDIDYAHADMM
The following text describes a protein:
Function:
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MLVIRWTVAICVFVLQAYAAVQDPASLREYDNFTNRSLLWAPYRANCYFGVRPRYVNAEPFLMGLMWMNTKTVEAIGKIRHFVDTQDDMTKYGWEMYDPRIGGKQVILDTVNNLNLTIYFVKSHDGVNWGFRVRGEALDKSSPLDSASIIYYMKQNGDSKENYLTSEQVTSDNKLRLTGYSGELGEYEVLISTVKGNSYKKAKVLSSEADPSRIAHLSMVVPDDRVWNANEIFQSLLVDSIQQYMAESDEDVELLQIPSAMTIRNIHNFAPSKFHFVQKTFDISESPFEIDFLYNKKGSQNPISSVDELIKPVLDTIRSKFDSRFEIKDARVRQFAIETLSNLIGGLSYFHGKQLVDRKTVFDEELFSSIELNHPEEEGPHDLFTFVPSRASYPRGFYWDEGFHLLQVMEYDFDLALEVLRSWLGLVEDDSGWIARELILGEEARSKVPKEFQTQNPHIANPPTLALAFSEMLNEVLGSGLLHFDLTDENLGSFSGNSGETLKKDHELLAAYSERLYEKLLAQFNWFRSTQRGMTEEYLDLADVDEDSIHVEDAYHWVGRTFTHCLPSGLDDYPRAQPPDMAELHVDALSWVGIMSRSMKQIAAILGRHQDAERFHKIEQNVIDNLNNLHWSEEHQSYCDLSIDDDLDTRKFVCHEGYVTLMPFALKLIATEDERRIRRMVEVLSDPDRLLSDFGIRSLSKMDEYYETGEVYWRGPIWVNINYLCIDALRYYFGEESDAEKYDHKLVKQAKQLYHQLRNNLLNNIIDVWEKDGYCYEQYNQNDGKGQRVQHFTGWTALAVNLAGKFPEYI
The following text describes a protein:
Function:
This is one of the chains of the nonenzymatic component (CF(0) subunit) of the mitochondrial ATPase complex.
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MPQLDKLTYFSQLFWLYLLLFTFCILLFNNNNGILGISRILKLRNQLLSRRGGGGGEIRSKDPKNLEDISRKGFSIGLSYMYSSLSEVSQWCKIVDYLGKRRKITLIYDFSKISGSRAMERQILYLISKSSYNTSSNWITCGKNVMLTHVPHGEGSIIL
The following text describes a protein:
Function:
Bifunctional enzyme involved in flavonoid metabolism.
Sequence:
MTHHKVCVTGASGFLASWLIKRLLLSGYHVVGTVRDPANEAKLAHLWNLEGAKERLHLVKAELTEEGSFNDAIMGCEGVFHTASPVLGHITNPREEILKPAVDGTLNVLRSCKKNPSLRRVVFTSSSSTVRVKDKFDPEKPVDESSWSSVEICEKYQIWYVLSKTMAEKAAWEFCNENGINLVTLLPSFLVGPRETERFKWHGRMGYVHIDDVALCHILVYEHEKAQGRYLCSSTVIDNDELVSILSSRYPTLPIPKRFEQHDRPYYEFNTTKITSLGFKFKSIQEMFDDCITSLVAQGHLSIP
The following text describes a protein:
Function:
SOSEKI proteins (SOK1-5) locally interpret global polarity cues and can influence cell division orientation to coordinate cell polarization relative to body axes, probably by guiding ANGUSTIFOLIA (AN) polarized localization.
Miscellaneous:
MISCELLANEOUS: 'Soseki' means cornerstone in Japanese.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=SOSEKI proteins (SOK1-5) integrate apical-basal and radial organismal axes to localize to polar cell edges in roots, pointing towards the endodermis, mainly to inner apical edges.
Domain:
The DIX-like oligomerization domain is required for polymerization, edge localization and biological activity.
Sequence:
MESNGGGGEVRRVNLVYFLSRSGHVDHPHLLRVHHLSRNGVFLRDVKKWLADARGDAMPDAFSWSCKRRYKNGYVWQDLLDDDLITPISDNEYVLKGSEILLSSPKEDYPNVEKKAWVTRNGGIDAEEKLQKLKLTSEKIQKESPVFCSQRSTATTSTVTEESTTNEEGFVLKKQDPKTVSGQRDGSTENGSGNDVESGRPSVSSTTSSSSYIKNKSYSSVRASHVLRNLMKCGGLDTNDAVLVPLNKSRSGAFGPAWEDERRYQYHQQHNARKSFEGAWSGIKMKETIEFCKPKVAPSKPSMAPLCSQCGKLFKPEKMHSHMKLCRGMKNSSANNDLMTSNNTVKPRQQRCRNIPGNPLGHQRVLTTTLKE
The following text describes a protein:
Function:
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.
Sequence:
MRFKMAAGVYVFFVSSVVCLLFCLSFAELYSEEDAVVRLDAVSLNRTIYNVPNVFLVEFYSSWCGHCVNFAPTWKALARDTQDWAEVIQLAAIDCADSKNLPTCRQYDIKGYPTIKVFQPFTQNTSDIGKPLKVGRASDKLVHAMVDVIEQHSLLNKPQHWPNLQPAHSSEVSEFFQTWKNVEYLALLFEANDSYVGKQVILDMAKHDNIMVRRVLKNEEMLMKKLAVEVVPSLYVLYRNGSAIQLARGGETRFDFRLALKKLPHLDRSQRHGEQLLLQPSAPTLEKTTAPRTPSMDNFNRSAVHMTDLLSALTYSFKQEIAGRQELEGQTLQAVQDFVKVLAKYFPGPPGVSAFLHNINRRLNPRKTKMTYQEWAQLLDEQEDASALPQEVRWVGCQGSQPHGRGYSCSLWLLFHTLTVQQAAEPDPTQNSQSVLLAMRAYITTMFGCQECGKNFQKEAVTMETDVATPDEAVLWLWRTHNRVNKRLHGDLSEDPQFPKVQFPPPWLCPSCHLAQGPETEPVWDEGQVLQFLKRHYGSANFIHDNPSLQSKDQGPHFHVQPTMVRRSDPRQPHKQTSQQELVGVHVKDLQGRLQRRHDPNFGIKVEKLPGNENRANPSGWGFSNLDISMCVMLYVLSSGLVVGLYVMFIVKRRRRRRTPPV
The following text describes a protein:
Function:
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. In neurons and together with DNA N6-methyl adenine demethylase Tet, plays a role in the maintenance of transcriptional activation for specific sets of genes.
Subcellular Localization:
Nucleus.
Sequence:
MVPIGAVHGGHPGVVHPPQQPLPTAPSGPNSLQPNSVGQPGATTSSNSSASNKSSLSVKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKSDT
The following text describes a protein:
Function:
Binds mRNA.
Sequence:
MPSSSNSAAFSLDEFAKALDKHDYHAEKGQTVHGKICQHANEGVYVDFGGKSPGFVPVQELGLRPHAEIEDSFPLDSAWDFLVTSEQNDEGQVRLSRRQLQIQQSWENLAELEESGKTLEMVVTGTNKGGVVGDVEGLRGFIPRSHLMHKDNMDALVGQVLKAHILEANQDNNKLVLTQRRIQQAESMGKIAAGNIYEGKVAKIQPYGVFVEIEGVTGLLHVSQVSGTRVDSLNTLFAFGQAISVYVQEIDEYKNRISLSTRILETYPGELVEKFDEMMADAPNRLPLVQSKQNLGDKQEQLEKS
The following text describes a protein:
Function:
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
Sequence:
MIFTSGANKLNDNRNVRTKISSNRQSIKTAPTKAAEIPEYLQLYQTPPGDDISLTEFDDIAMERLKLLKSFENLKDSVSLYNDEFKDKFRKLCDGTKLIVFPDQKPPHQEEVYELWRRDNIGHFILRLAFCRTPENQKWLTQIEGDFLRFRLRQEREQVLDSALANVNFTIEKLGYTEKQAMIEDLEAACQFNLFEAPNKTFYKVDFIDAIELIRRGSVHLKKGFAYFPFDDLVTILVTKMKNNMMAAMARSFKHLAILEEEGRLLPRLSLLSNNAYSGKDYNGEQPDGSIIVTRHMIDKLSRRSFAPCMKQMHNHLRVNHHLKYGARRQYGLFLKGIGLSLDEAIAMMRDEFTKKITSDKFDKEYGYNIRYMYGKEGRRVAQTAMSCATIILRNPPSAVDCHGCPFRHSEKQVLKQKLGSDAILKKEQIERIAELAELNQYDKACTRYFEFMHNLEEGGLGQLITHPNQFYEESQKIVAERIAAKQESQEAPAPKIEKMDTE
The following text describes a protein:
Function:
Modulates transcription of respiratory genes in response to changes in cellular NADH/NAD(+) redox state. Binds to the DNA sequence motif 5'-TGTGAACGCGTTCACA-3' in the promoter of the cydABCD operon. May play a general role as a sensor of cellular redox balance.
Subcellular Localization:
Cytoplasm.
Sequence:
MATGRAHRPATRSRGIPEATVARLPLYLRALTALSERSVPTVSSEELAAAAGVNSAKLRKDFSYLGSYGTRGVGYDVEYLVYQISRELGLTQDWPVVIVGIGNLGAALANYGGFASRGFRVAALIDADPGMAGKPVAGIPVQHTDELEKIIQDDGVSIGVIATPAGAAQQVCDRLVAAGVTSILNFAPTVLNVPEGVDVRKVDLSIELQILAFHEQRKAGEEAAADGAAPPVAARKQQRSTGSADQGPDGDVPAVMPA
The following text describes a protein:
Function:
Binds together with bS18 to 16S ribosomal RNA.
Sequence:
MAKVNTYETLFILDSNHYARDPGGVAKQLEELIAENGGEVQVSRMWMEQKLAYPIDKHQKGTYYLIYFSMEGPNLTQLARAFALAEPVIRELTIKLDPRLVEPILANARGEHFTGPAGAEGSDDESTESTDEAVAETADA
The following text describes a protein:
Function:
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKETLEITPDLLKNPYQKIINASASVFDEKHGRSFFSTQFYEKIEPYLKEVLTHPIDLECDLNTAKKKNRLTPLKQLFKACFNTEEILIVNNNTSAIFLIANALAQEKEIIVSYGELVGGDFNLKDILLNSGARLHLVGNINRAYLRDYRLALNENSKILFKTHNPHFKKDTPFKDLQTLAKEHDLIDYYNLGDVDLSNRVALEEILALKPSLLSFSADKFFNSAQAGIIMGQKERVEALKNHPLYRVLRVGKITLTLLFCSLKAWINHQEDITIHALLNQTKDALLQKALKLYALLKPLELNVSIASSFSKIGNLFGRELESFCVKIQPKNTRALNSEKLYLKLFQKGVIARISCEFVCFEVFSLNEKDFEKIALVLEEILNKA
The following text describes a protein:
Function:
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity). Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity). Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
Subcellular Localization:
Peroxisome.
Sequence:
MNPRLRHWREAASVLLAAGAPGRRSPSPLGPCDYELLFLQRSSRSGFMPSAHVFPGGLVEAADFSAEWLRLLPAAPRCGLGAVRPPPPGGSRAPLFATDRQPLGSPLPGEVAFRICAIRETFEEAGILLLAPGGRPREGSGPAPSLPAEQLLPAAELGEWRRRVQEDPACFLQLCQRLGRVPDIWALQEWSNWLTPVGRAGRGGRRYDTAFYLCCLETRPPHTSQDNQEIAAFLWSSPPEAIERFKSQEIWLAPPQFYELCRLCNFSSLNDLHKFSSDRALEGCERWLPVTLTAADGFIQLLPGDELYPEDPDYTGEKKITMSTDKMVEDLMKEGSVFHRIVIKNTHSLAVYVNIQAKYKHMNPLMINTDSSNYNSRL
The following text describes a protein:
Function:
Putative role in tail stability.
Subcellular Localization:
Virion. Note=Component of the tail. Located on the side of the baseplate, at the level of the cone formed by the BHP-pb3 trimer.
Sequence:
MSLSDLARQIIKEQLDTASRSENNKNTVVYSVETGLKDPTRDGTVAQVSFKFSKPVSQDLLNIRTASILKAVSSSLDLSGDLGALENLIQATAGKKSSVGKKRSTGRVQVNFGDPSDVEDGYSGAVTGASGRFVSNSNMKIILEIVAKEYLIKDMKKAGAPLKFRTGRFANSLKIKDVMLRDSETSKGSPELNVTYNYMTRPYSVFNPAVSTYRRLSLRPYPGARNPQKLIGEAIAKAARDLIHSRYKIKVNQGT
The following text describes a protein:
Function:
Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia.
Subcellular Localization:
Endoplasmic reticulum. Golgi apparatus. Melanosome.
Sequence:
MPVDLWLLSIRGLPGSRKNQKMQLKATEPSLKQGLGMPEETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIVDVFLMLGPSVLDVFRQHASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPQMRAWWANMFNFHNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHQEGFPVMRPLWVQYPEDMSTFSMEDQFMLGDALLIHPVSDAGAHGVQVYLPGEEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKEDPITLFVALSAQGTAQGELFLDDGHTFNYQNRHEFLLRRFSFSGNTLVSSSADPKGHLETPVWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLTLRKPGVNVASDWSIHLR
The following text describes a protein:
Function:
Centriole-enriched microtubule-binding protein involved in centriole biogenesis. In collaboration with CEP295 and POC1B, is required for the centriole-to-centrosome conversion by ensuring the formation of bona fide centriole wall. Functions as a linker component that maintains centrosome cohesion. Associates with CROCC and regulates its stability and localization to the centrosome.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Midbody.
Sequence:
MAATGDLKNNIHKLLSELKHIKYPMELDYQGITTGTTSAFLPVLHHALLEFSRPVSTEINDMGIELYGKTDQRFVEGVYKVLRDVFQYKSTITKDKFLNAGFAEHKVILAYDVLKMVQEKHRRITGPKAKPAPSQTNAGAGMFQRGTAMRRSLKQQKNRERNLSPVQRSSVDSSSMSGSPKETSMLYSAGSVEVIDLDNTGLPGPPKVISAPPLMLDELPAMTEPMDIYAENPRGDPPRKKGGADTGYHSTETSPKDQVSLKHRVESLEGRMKVMEEKLETVVQTSYKNIQGENAPPTGFTLTPEQVESILGRLLLVENRLRIVEAKNQASSAGESTSKVVLPQGLPTDGCSILNNLNSPSSQPAKTLTFDPLDLSTKSPVSSPPRKMTNDGQPGSTPSAHVAPFQFENKQTEEKMAKLEKMFEETMSLLKKSHDPSNNS
The following text describes a protein:
Function:
This promotes the activity of RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MAATAPLEISLPETKSCKISKLKVKSGSKVSRGSVLLLYKFENGDGSGGEKESEQKLKSQQVGTVQDILANEGDEVKPGSVVLRIARCSHPTVMKDMCAECGEDLRKDEEVKQTPATKACVSMIHSIPELHVSKEEAAVLAKLDEDSLIKHRKLVLLVDLDQTLIHTTLDEVPADMPGVHHFQLRKGPMFPWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKFFSHRILSRDECVDPHSKKANLRSIFPRGDKMVCIIDDRDDVWNFAPNLIQVPPYRYFEGTGDINSPVNLNDRNNAPVKKPRESPTKYTSSPASQKGEGDDNSRDAESKEAKGAVSKEAEEEEKTTKEENKAVDEKSEVCSSEVSSTTKDSEEESSDKVDEGRGKGSGEGDKKEASKDEMEEGELAQEKESDSDKVTTTDGTSTGATSPEEDKDEYLLYLADTLARIHRTFFKQVEANPQELPDLKSIVPAMRMSVLKGCNIVFSSVFPTNMPPEQSRVWKVALALGAKVSPQIVTKSKEEQAKGRASTHLVAAKVGTSKVHAARRSKSIFIVEPDWLWCCWERWERVDERLFILADVSKHGSRSSTPGFSDTESTGSQKAKKGKGKAKASTNGNPGSTGMPGQRTKSRPLSMSEDYNPMYSFSSEDLASMGKEVEDMFGSSSGESSSSSSSSESEDEARSNPTSLGSVTRPASSSSSEESLTAENPRGWKRKRDEMEDKDDDVNDFDPFQRPVEDSSSSAGLSEGEEWFSEEEGQKMANAIDDLLTYKRSVRKWDEG
The following text describes a protein:
Function:
Cell surface proteoglycan.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MLHQQQQQQHLHCRRKATATTTARLVIFSSPLLLLLLTTHLPPTLQADNGPAPQVAALAAPNPAGGVAGSSIIDQFSPNCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGYTEKPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKRSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGKSGNGGGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIASSSDVDGMCWNGHTIDRYMHSITTEHGSNPEFTGNPASTKQTAQMASQLSHLKNAIVHLRNAYNGQDVEWSEQELPYAGSGAGSGSGSEDDEDDDEGSGLGPFEPSHKPDVERPSVDADNDDDEDAGGRGHMPTHTSRPTSGVDDKNPLIHTTHFDQDHNDLDEDHRQLDEDEDTDAGHDGANDNRSSDAPEKMTLRRALVVYLLPLYMAWFGGVCADLL
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MAEPPEQASSDPTTPPQEDNQSTKTNSKKNRGTKKSKRAGASSLCSSTMVEDPFFVLAGGKEGGFLELEEIDEADFGIVGGYVEEVGADEGKAGKDRGKKKKKRKRKRGGDDQVLSGDGDSFLKQCDGDSVVENEQEGEKEKKNAKGKRDRKKRKVKDSEKSGESGKDIADDDNAEDVQDKNENMEQDKDDDLILGEDDVFAWHELRLHPLLVKAMRRLGFKEPTPIQKSSFPAAAHQGKDVIGAAETGSGKTLAFGLPILQRLLEEREKASRLHQEDEKMEESAGESPLRALILTPTRELAQQVCDHLKEAAKFLGIGVIPIVGGISMEKQERLLKNKPEIVVGTPGRLWELMSMNNQHLVELHSLSFFVLDEADRMIERGHFHELQSIIEMLPLTNGSDEQAARTMPNCETVPILQIKKRQTFVFSATLALSSNFRKKLKRGLSTSKASTDDVSSIEALSKKAGMKPNAEIVDLTKASILPEKLEESFIECSEEDKDAYLYYILSVHGQGRAIIFCTSIAALRHISSILRILGINALTNHAQMQQRARMKAVDRFRGSENSILVATDGFARGMDFDDVRTVIHYQLPHSTDVYIHRSGRTARKSLAGCSIALISSADKSKFYSLCKSLSKENANKSWLQRNAESMGLILETSDSEEERVKGHKQRKATSAHLQKLQQELSDLLQRPLQPNTFSRRYLAGAGISPLLQKQLEELAKRKVSNNRSKTENKGSRFVVIGQDRVEPLQALQNSGQEVCVNLDKQREKRRLAQNWKQKKHEEKKRSREQKRKEKRKAKAMD
The following text describes a protein:
Function:
Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.
Sequence:
MPHKKRCHGRKKNKKENGDTSFQKQEYAPQTSRFMSQQVTPTTTSQVSTVKPAQYEKGATQSSTAAATVKSGAGDPATTQKGSSQVKPQVTDSKSTPASSAKVSAVSSGTGVAGTTGGAGVKPADPAKDTPQSTTIPSTKLGPAKVDPAAGKPSGSAGAQKQTSAQKVQVEVGPSAAKVSADADDPFDALSGTLPSSQPLAPKVHYTGPEIKEPKLKSEKGVLCGERDDTLPPGYRKEDLEKKHGAGVPAGVPEKPKEVPKPISTDDALESLSSTFVSPAQAAPKKTDVKTETIGAVDVKSAGTTNFAPPPPSQQKQPASSQAAAVTKSPAPPADKKAKMETHAQPAKAKTESDSSISLDALDALSDTLGASKPPQKLPELKPGQIVDEKKQTSEKGVRVGERDDTLPPQYRFKEEDLKKYPPPAKEPSLNTDDAMDILSGDFTTPASAPVVKAPVPPAQDTKKHAAVPEKTKDIPKTKADALSSDFVAPAHSAPKVSSAAPKTIPPGPPQTPDEDPFSALGDTLSAPEPPKKQPDLKPKDIVHEKDVTSKKGVRVGERDDTLPPEYRFKEEDLKKYPPPQKDPSLDANEALDILSGDFTTPSAPSAVSPASKSSAKSSDSALDALAGDFVASSSASSVHSAVSGPPRSDRLLSDGTSSALDALSETLGDIKAAPEPAPVLPKTVVKEKTVIEERVSKPGERDDSLPPDQRFTAEDRKAFEEAKKKDAKPKQPSMDDSAALDMLSSDFSDVPTVKPTVSDGKSFTPEPTPPTFKATGPVLDKLADNVLSNLTDPKAKDSKAKGKGAKPKSKPKKQAVEDSSATDLLSSKPSSDVVPSASTKAGKR
The following text describes a protein:
Function:
Plays important roles in both rhabdomere development and in photoreceptor cell survival. Might function as a calcium-sequestering 'sponge' to regulate the amount of free cytoplasmic calcium. It binds 0.3 mole of Ca(2+) per mole of protein.
Subcellular Localization:
Cytoplasm. Note=Hypodense compartment.
Sequence:
MEPGTIPSPVSAPVAAPVTPSAVAAPVQVVSPAAVAPAPAAPIAVTPVAPPPTLASVQPATVTIPAPAPIAAASVAPVASVAPPVVAAPTPPAASPVSTPPVAVAQIPVAVSAPVAPPVAATPTPVAPIPVAAPVIATPPVAASAPTPAAVTPVVSPVIATPPVVPANTTVPVAAPVAAVPAAVPVVAPVLAPAVAPAVAPVVAETPAPPPVAEIPVATIPECVAPLIPEVSVVATKPLAAAEPVVVAPPATETPVVAPAAASPHVSVAPAVETAVVAPVSASTEPPVAAATLTTAPETPALAPVVAESQVAANTVVATPPTPAPEPETIAPPVVAETPEVASVAVAETTPPVVPPVAAESIPAPVVATTPVPATLAVTDPDVTASAVPELPPVIAPSPVPSAVAETPVDLAPPVLPPVAAEPVPAVVAEETPETPAPASAPVTIAALDIPEVAPVIAAPSDAPAEAPSAAAPIVSTPPTTASVPETTAPPAAVPTEPIDVSVLSEAAIETPVAPPVEVTTEVAVADVAPPEAAADLIIEPVEPPAPIPDLLEQTTSVPAVEAAESTSSPIPETSLPPPNEAVASPEVAVAPITAPEPIPEPEPSLATPTEPIPVEAPVVIQEAVDAVEVPVTETSTSIPETTVEYPVAEKVLDPAITEAPVTTQEPDVANINDGAPATEITTPAVEIVTAAAEVSDTAIPLIDPPVPQEIAVAEIPETETKPAEVIVEQSTIPIEAPVPEVSKYAEPVISEAPAAEVPITAGDNPDNTSVGISEVVPTIAEKAVEEVPTSEIPEQSSSPSDSVPVAKITPLLRDLQTTDVSLLAIAATLDAIGEKLKDQKARNQQVMDRLCEIEKILGPPKSN
The following text describes a protein:
Function:
Binds double-stranded RNA.
Sequence:
MATTAAAAAPVPGAIPAAAPAAPSAQPHPVPDKCTNYKNHLQEWTQRNDQKLPAYNTESKRDHHRLEFRSTVEVGGERFQSARNHSRRKDAEQDAARVAYEILVTKTVNDDDHTDALGLIDQGVVFCKSILHEFAVKTKVDQPTYSADHPEGVSPMTLFVSSVLFAGNTYTGEAATCKKDAEQKAARVAVKSILATKNTCMHQIVRSKKELIIAITSSGFNKERGVVSQENCNAPTNAITPIKFVPAGEAAGLTADQGATNVPEDDPCAQAVSGSEKRKKHRKV
The following text describes a protein:
Function:
Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration.
Subcellular Localization:
Vacuole lumen.
Sequence:
MLSQSFLIALAVIPVTLASPYYNPYFGKYFHGQRTSGDSSSSGNFYPVKDCSAFIDQNPETSWSCHNKSPVSSANSCCFEENGIILSTQFWDYNTTLLEIAVNGSTSDIVEAELKSKLDTVYNDLSRTFTIHGTWDDFCNGSYPQYCNKSLEVSDEKDNLTHILVDQFKEVELYNIMSKYWIDTIASNVDSSASTALWEHEYNKHGTCMTTLSPSCFTSQSYTRFENVVNFYKKTVEIWSQLDTFEFLAAAGIYPTVSRKYKLSQVQEALQKAHGAEVYVGCLNNSISEIWYFYNLQGSILTGTYKPIDTTTNTKCKDEVWYIPK
The following text describes a protein:
Function:
DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Subcellular Localization:
Nucleus.
Sequence:
MFPLSTVNLTNNRIKTLRNLIERNGGTIELNSRTIMIVGSDATSESCQKQLEKMHLNFEQYRQQFINADWISQSLQAKNLLDFKKYQLFSEIEQKQKRVSPQSTDTKFVYIESLAKTVPLKEDAEDSLDMESGEYTIIKPEMREKYEKKKQEFKRQMIKENRFLLDYEYDKDLDNYHHQVDDGYEFLLDNFQILKKEEFDAPQQNKFYGDEDCQITEIRKPSIDIFQGLDMGKALVNVDQPLVNAQIKETKQFQPGSKQQIQYWENKREFFICDAGSAQKCYNNQIIEELEKLLKIYTNEKDKGRCIAYRKAIGYIKSLTFPIRSSEDLKEMPTIGEKIKNKIIEIIQTGQLVKVQKLQGQEKNVAITQLSRVWGIGPTTAATFYFKGIKTLDDLRKNQHLLNRNQQVCLQLVEELEQRIPRDEATIIYDIVKREIDDLSGVPGLYKATACGSYRREKETCGDMDILITRCDGKNTDGFLLNLIQRLEGKLLTHHLTIPRRGEHDTESYMGIGRISNNAIHRRIDLKFYPKEQYGCAVLYFTGSDQYNRSMRLWAQKIGYSLSDHGLYPTQRGSQNKELWKGEVIACEEEIDVYRILGLQYKPPKERSV
The following text describes a protein:
Function:
Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MPAKQRMRIASEKYSKNVTQRGAVPKTQYYAILWCYRNTKRKRLVIAFNHVCMLFPLSINNNVDQGYLMPFAQELLCLHATNNFEEIVECAIDRYNKSRLFTAASGDTAYKGPLYSRRLYSTYKTCKTVHSPKQDKAPVGPIVLGLFIFLVCGSGLIIIVTPVDCSVRKKTPDTTKIGALTCKFKNDHTET
The following text describes a protein:
Function:
Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.
Subcellular Localization:
Nucleus.
Sequence:
MAKRRSRTSKLIKTKKVQPKLEAAFTCPFCNHDKSVSCTLDKKLKVGEAQCGVCKESYATTIHHLTEPIDIYSEWVDECEMINESEELRVDDHRPTEPIGIYTEWVDECEEVNESEKLRDDTRPSKKRRSVTDFWDDQVASL
The following text describes a protein:
Function:
Involved in the biosynthesis of the siderophore staphyloferrin A. Catalyzes the ATP-dependent condensation of a citryl-D-ornithine intermediate, produced by SfnaD, and citrate to form staphyloferrin A.
Sequence:
MVYLEWAKADRNIQYRVINAIIKERIYPEQTFISQKGSLIEIQYHMHVLTIEVVRKSALERYEFTGDITYLNKGETSLIITLEGLLDVLNHDFDIPISERLREELIHSRDSLVETYKQMSHRQTLISQSFKFSRLPQDINFFSWLQHVKDSDKTDDLTYSESLVPEGHPTHPLTKTKLPLTMEEVRAYAPEFEKEIPLQIMMIEKDHVVCTAMDGNDQFIIDEIIPEYYNQIRVFLKSLGLKSEDYRAILVHPWQYDHTIGKYFEAWIAKKILIPTPFTILSKATLSFRTMSLIDKPYHVKLPVDAQATSAVRTVSTVTTVDGPKLSYALQNMLNQYPGFKVAMEPFGEYANVDKDRARQLACIIRQKPEIDGKGATVVSASLVNKNPIDQKVIVDSYLEWLNQGITKESITTFIERYAQALIPPLIAFIQNYGIALEAHMQNTVVNLGPHFDIQFLVRDLGGSRIDLETLQHRVSDIKITNDSLIADSIDAVIAKFQHAVIQNQMAELIHHFNQYDCVEETELFNIVQQVVAHAINPTLPHANELKDILFGPTITVKALLNMRMENKVKQYLNIELDNPIKKEV
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MKRFSFSDSSGKLLYPTEEKNTENLGYSNEFQAMLDGLEDEDGIEESGCGTGKKRRLRVDQVQALEKIFEVDNKLDPDRKVKIAQELGLQPRQVAIWFQNRRARWKTKQLEIDYNILKANYEALQHNYSKVEQEKEGLITELKGLKEKLGEETISPAFQRPQELILNKLKNSSDFVDSKDGSSDSDSSGVMNEENYTNTTTLNYQQLMPKVSSYNNALDHLSLSSSTYTQLLDHPRASNSTSSSMRGYNNNNDHQQQGVGRMEEQNGFTTEDSCNIYSVDQAPNLYWYFSDHRN
The following text describes a protein:
Function:
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
Sequence:
MKTGILGGTFNPVHVAHLRIAEEVRDTFALDRVLFIPAASPPHKAMEGEVPFETRCAMVRLATADNHAFAVSDMEGGRPGKSYSVDTIRALKEEYPGDEFFFIIGSDSFLDIGSWYDYEAIFASCNLVVAARPGAEAADLLAALPVAITAQFCYYPAEKRLAHRSGYSVYWLAGVPLDISSRSIRGLARLGRSIRYLVPEAVERYINEQRIYAHDG