lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSPQRMKLSSPPVTNNEPTATASAVKSCGGGGKETSSSTTRHPVYHGVRKRRWGKWVSEIREPRKKSRIWLGSFPVPEMAAKAYDVAAFCLKGRKAQLNFPEEIEDLPRPSTCTPRDIQVAAAKAANAVKIIKMGDDDVAGIDDGDDFWEGIELPELMMSGGGWSPEPFVAGDDATWLVDGDLYQYQFMACL
The following text describes a protein:
Function:
Part of the ABC transporter complex PstSACB involved in phosphate import; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLARAGEVGRAGPAIRWLGGIGAVIPLLALVLVLVVLVIEAMGAIRLNGLHFFTATEWNPGNTYGETVVTDGVAHPVGAYYGALPLIVGTLATSAIALIIAVPVSVGAALVIVERLPKRLAEAVGIVLELLAGIPSVVVGLWGAMTFGPFIAHHIAPVIAHNAPDVPVLNYLRGDPGNGEGMLVSGLVLAVMVVPIIATTTHDLFRQVPVLPREGAIALGMSNWECVRRVTLPWVSSGIVGAVVLGLGRALGETMAVAMVSGAVLGAMPANIYATMTTIAATIVSQLDSAMTDSTNFAVKTLAEVGLVLMVITLLTNVAARGMVRRVSRTALPVGRGI
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSIMSKFEHGMERVLVPVANKLNSQRHIAAIRDAFILVFPLIMAGSIITLINFAVLSPDGFIAKILFLGKIFPNLADAQAVFSPVMQGSTNIMAILIVFLVARNLAIFFKQDDLLCGLTSIGAFFIVYTPYTVVDNASYMTIKFLGAQGLFVAIIVAIITGEVFSRLARSPRLMIKMPDQVPPAVARSFKVLIPVIIITILFSVINYLITLIAPEGLNDLVYTVIQAPLKDMGTNVFSVIIIGLVSNLLWVLGIHGPNTVAAIRDTIFTEPNLDNLSYVAQHGSAWGAPYPATWAGLNDGFANYGGSGMTLGLLIAIFIASRRADYRDIAKLSLAPGIFNINEPVIFGLPIVLNPIMVIPFIITPAINTLIGYFFISTKLIPPVAYQVPWTTPGPLIPFLGTGGNWLALLVGLLCLAVATVIYLPFVLVSNKIAASDAAMDKNATASTEQ
The following text describes a protein:
Function:
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
Subcellular Localization:
Cell membrane; Lipid-anchor. Cytoplasm, cytoskeleton.
Sequence:
MSEFWHKLGCCVVEKPQPKKKRRRIDRTMIGEPMNFVHLTHIGSGEMGAGDGLAMVLLSVTPTLSSPEEMLPPPDASYNQCPQGLSFPYSPNSASKGLGAGLPLLPLARAPPGDGVKAAGLTNDYWLARGAQLKPWTLSDLR
The following text describes a protein:
Function:
Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MVSCQTFFNTNTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTTRGALSLSLSLSLSLSHSFSLSLISFSLGHLRMGKKVKTGKDRRDKFYHLAKETGLRARSAFKLVQLNRKFNFLQQSKVCIDLCAAPGGWMQVAAQNMPPSSLIIGVDLVPIKPIKGCIGLVADITTERCRQMLRKEMKHLKADVVLHDGAPNVGTSWIQDAFTQASLVLKSLKLATEFLVEKGTFVTKVFRSRDYHALMWVFKQLFRKVQATKPTSSRNVSAEIFVVCQGFLAPDRIDPKMLDPKYVFEEIDDGQTLPDIFKDPKRKPRAEGYDDNVKQSMFTSITAEDFVKSDNHLDLLAMHNQIVFDDDSLIAKHPATTGEVRSLAVDLKVLGKKDFRTLIKWRQQMAMMLEEAAKLQRAAEGADGEGSEDEEEDEEGEGSEEDGESADSQDELETALAEAKAEEKAKLKRKRRLKAKEHRKLRERMALQMETPMDMAEDTNERILFNLKAVKNADQLAALDEGDMEAAMDPLMEVADEARPRRHITLDLSEEGSHAMMEEALERDYEQYLERKNKKKRVVRHHNKSSVIEARVDGQDADGDDADFAAAAPASVAADDEDEALENDTGLLVRSASKQRNTAAMWFAQNQFEDLDEDLDLDDEEEERAAALRKGATSSTNGGPASKRRKTAEELAKEYANEEWAEAMGLQFHADDLDESDGELDSADEFDDEDEDDMEGLNTASRRAAAVARARAQAEAAAEAGEDGDEATEQNADFDAAFAQLDQALGNDTKQLAVQAAVGDQVPTKKGDKGRNQGGGFEEVPMDTPESSTNRPGLDAAGLAMATEMIVRRKRREMIEAAYNRFAHNDDPLPMWFADEENPHRERIIPTSREMADEIKQRQREINARPLRRVLEAKARKKQRVGRALDKLTKQAEAIAENDSLTEREKGRQIQQLYKQYNRSRNQKRETTYVVAKRSLAAKRAVRPKGLTGRYQQVDQRMKADRRGMRASARRQKKAAKHRH
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MLRTTPKVNKIYLLIRAKDKEAAFHRLKAEIMESELFKCLEEMHGETYKLFIQNKLIPIVGNIYEPNLGMDIITSDKIAQEIDLIVDSAAITTFDERAKLYGWQDTYSFTKAIGEMMINNMRDEIPILIIRPSGITSSYKEPFPGWIQGFRIVDPLVFFYRKGDLPGLLADPNCLVDLVPVDMVVNTTMAAMAKHGNLQNPQLNVYHVASSSINPVSFSQIFDYSYDFFQLFPFVNSKGDKYEVKKMRFFDKISDFENYIWEVLSKQHEVQDGKELTKIQIRLIKKKVEYLKNFSKLYEPYLFYKGWFDNGNVRKLMGDMSEEEKRSFEIDVTKINWKNYIENTHIPGVQKYVLEGKRVN
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
Miscellaneous:
MISCELLANEOUS: Present with 3260 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MATSVKRKASETSDQNIVKVQKKHSTQDSTTDNGSKENDHSSQAINERTVPEQENDESDTSPESNEVATNTAATRHNGKVTATESYDIHIARETAELFKSNIFKLQIDELLEQVKLKQKHVLKVEKFLHKLYDILQEIPDWEEKSLAEVDSFFKNKIVSVPFVDPKPIPQNTNYKFNYKKPDISLIGSFALKAGIYQPNGSSIDTLLTMPKELFEKKDFLNFRCLHKRSVYLAYLTHHLLILLKKDKLDSFLQLEYSYFDNDPLLPILRISCSKPTGDSLSDYNFYKTRFSINLLIGFPYKVFEPKKLLPNRNCIRIAQESKEQSLPATPLYNFSVLSSSTHENYLKYLYKTKKQTESFVEATVLGRLWLQQRGFSSNMSHSGSLGGFGTFEFTILMAALLNGGGINSNKILLHGFSSYQLFKGVIKYLATMDLCHDGHLQFHSNPENSSSSPASKYIDEGFQTPTLFDKSTKVNILTKMTVSSYQILKEYAGETLRMLNNVVQDQFSNIFLTNISRFDNLKYDLCYDVQLPLGKYNNLETSLAATFGSMERVKFITLENFLAHKITNVARYALGDRIKYIQIEMVGQKSDFPITKRKVYSNTGGNHFNFDFVRVKLIVNPSECDKLVTKGPAHSETMSTEAAVFKNFWGIKSSLRRFKDGSITHCCVWSTSSSEPIISSIVNFALQKHVSKKAQISNETIKKFHNFLPLPNLPSSAKTSVLNLSSFFNLKKSFDDLYKIIFQMKLPLSVKSILPVGSAFRYTSLCQPVPFAYSDPDFFQDVILEFETSPKWPDEITSLEKAKTAFLLKIQEELSANSSTYRSFFSRDESIPYNLEIVTLNILTPEGYGFKFRVLTERDEILYLRAIANARNELKPELEATFLKFTAKYLASVRHTRTLENISHSYQFYSPVVRLFKRWLDTHLLLGHITDELAELIAIKPFVDPAPYFIPGSLENGFLKVLKFISQWNWKDDPLILDLVKPEDDIRDTFETSIGAGSELDSKTMKKLSERLTLAQYKGIQMNFTNLRNSDPNGTHLQFFVASKNDPSGILYSSGIPLPIATRLTALAKVAVNLLQTHGLNQQTINLLFTPGLKDYDFVVDLRTPIGLKSSCGILSATEFKNITNDQAPSNFPENLNDLSEKMDPTYQLVKYLNLKYKNSLILSSRKYIGVNGGEKGDKNVITGLIKPLFKGAHKFRVNLDCNVKPVDDENVILNKEAIFHEIAAFGNDMVINFETD
The following text describes a protein:
Function:
Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
Subcellular Localization:
Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm. Secreted. Note=Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha (By similarity). Does not have a cleavable signal peptide and is secreted by a non-conventional pathway.
Sequence:
MEAARCAPGPRGDSAFDDETLRLRQLKLDNQRALLEKKQRKKRLEPLMVQPNPEARLRRLKPRGSEEHTPLVDPQMPRSDVILHGIDGPAAFLKPEAQDLESKPQVLSVGSPAPEEGTEGSADGESPEETAPKPDLQEILQKHGILSSVNYDEEPDKEEDEGGNLSSPSARSEESAAASQKAASETGASGVTAQQGDAQLGEVENLEDFAYSPAPRGVTVKCKVTRDKKGMDRGLFPTYYMHLEREENRKIFLLAGRKRKKSKTSNYLVSTDPTDLSREGESYIGKLRSNLMGTKFTVYDHGVNPVKAQGLVEKAHTRQELAAICYETNVLGFKGPRKMSVIIPGMNMNHERIPFRPRNEHESLLSKWQNKSMENLIELHNKAPVWNDDTQSYVLNFHGRVTQASVKNFQIVHGNDPDYIVMQFGRVADDVFTLDYNYPLCALQAFAIGLSSFDSKLACE
The following text describes a protein:
Function:
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MSHPSPQAKPSNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGPTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDKEGLLSMANAGSNTNGSQFFITTVPTPHLDGKHVVFGQVIKGMGVAKILENVEVKGEKPAKLCVIAECGELKEGDDWGIFPKDGSGDSHPDFPEDADVDLKDVDKILLISEDLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQAELLKVKQKIKAQKDKEKAAYAKMFA
The following text describes a protein:
Function:
Component of the gamma tubule complex that is required for the regulation of both interphase microtubules and mitotic bipolar spindles.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Localizes to the SPB and also to the equatorial MTOC.
Sequence:
MVRSISSVLAKEESENGSPIPALEEGSVYHVSLKSEGVSPFSDRIQLNYLYDGKTFSDPSNLNIHQQEACLINELLNAFMGMEGVFVHLQDMKASSEFETIIMPPSFYILPGFDLGIKDIASEMLEMGSHYLSITAFIESRSHFEYGFVNHALCAALRKFVMDYVVLIMQCENQSRIDPNFSLQTLRLYTLPTSRSLRQVYLILRDLLLSMEKNASSSDDLGLSNIDDLLEQLNEGNDISHVVNATRSKKKVCKGGQVISFLTESLTKYAGDPVARKILTYLLREASRPYTKMLNEWIHLGLVNDPYDEFMIKIHKGITSMQLDEDYTDEYWEKRYVIREDQVPPQLLDLQNKVLFAGKYLNVVLECRKGVNNLASLNAKDDTQNQLLWPSTFDDDNFTLNIMNAYVYANESLLQLLQSSQSLYAHLYSLKHYFFLDQSDFFTTFLDNAQHELRKPAKYISITKLQSQLDLALRQPGTITATDPHKEYVTVEVNQTSLIDWLMHIVSISGLEEGTSSQGNEVWNESITKQADVGNETRNFESEHNRSTQGTSKVGSDKDINGFETMQLCYKVPFPLSLILSRKAIIRYQLLFRYFLLLRHVEMQLENSWVQHSKNSAWRLNSSNAKIEQWKRNSWLLRTRMLSFVQKIIYYTTSEVIETHWGKFMGELENARTVDNLMQEHIDFLDTCLKECMLTNSRLLKVQSKLLNTCAMFASYTSTFTRSLYLLENSEESFDEGRMDKMEEILRRYEDSFSRHLKSLVNACNYFASTETAALLSLVMKLTG
The following text describes a protein:
Function:
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
Subcellular Localization:
Nucleus.
Sequence:
MIQHENNRVQMTKMRLLREYHIKVLDNWLSECVSFCVQENPTISNEGVFQFAFSQWLLADLKEIGTGVLPPGLAQKGEQHTMSGSFPVQMQYLMDISEPAYDQWRALYDKKLDEADDEVQMRKSQAPNVKKRRMLKLELTDGKQTVVAMEHSPIRCLNTKLTPGLKLLLTGPLRCINQVIFLEPRNVRVLGGEVDVLLITNAYENVLLRALNKPANPTPKLDYEEPDVSEARHRANYSAIQSIPMGRNAGGGSSHHQVPNQRAHQRKSPAIVEDDVDDSLLMGIDLDMIESTQPKPEQVPTVSTLMDDDDMDAFAVQLVDVPREPEIMHHQVSSTKQSQSSPVARKVAPAPVRCPEPTYEGLIEDDIDVMNALEDQIQSELRGFDRLDEQYDEVAPPMAKKSRPSDEYRQEQREMETLPQPAASSKSKSPEPAPTTSKKFNQFTTSDLFEDSMDGMDALELNERPTTLSIISPSYPHRIDGTSLATIDQLMALPEEQRRSGAAFVVYCEVEAVTEQPRIRREQWNLSVELTDLSAVRLPVRLHDRVISRMTRHDAAELMRLRKTDRDGVMKLLDRILSELKELLQDIKCFWRVVYEPESDSALSGGQPLQPVVMETYEMSEERGAILLEKIIKENCSQLRKLL
The following text describes a protein:
Function:
Involved in nonsense-mediated decay of mRNAs containing premature stop codons. It interacts, via its C-terminus, with NAM7/UPF1. Could be involved in determining the efficiency of translational termination or reinitiation or factors involved in the initial assembly of an initiation- and termination-competent mRNP.
Miscellaneous:
MISCELLANEOUS: Present with 1280 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MDDGRKKELHDLNTRAWNGEEVFPLKSKKLDSSIKRNTGFIKKLKKGFVKGSESSLLKDLSEASLEKYLSEIIVTVTECLLNVLNKNDDVIAAVEIISGLHQRFNGRFTSPLLGAFLQAFENPSVDIESERDELQRITRVKGNLRVFTELYLVGVFRTLDDIESKDAIPNFLQKKTGRKDPLLFSILREILNYKFKLGFTTTIATAFIKKFAPLFRDDDNSWDDLIYDSKLKGALQSLFKNFIDATFARATELHKKVNKLQREHQKCQIRTGKLRDEYVEEYDKLLPIFIRFKTSAITLGEFFKLEIPELEGASNDDLKETASPMITNQILPPNQRLWENEDTRKFYEILPDISKTVEESQSSKTEKDSNVNSKNINLFFTDLEMADCKDIIDDLSNRYWSSYLDNKATRNRILKFFMETQDWSKLPVYSRFIATNSKYMPEIVSEFINYLDNGFRSQLHSNKINVKNIIFFSEMIKFQLIPSFMIFHKIRTLIMYMQVPNNVEILTVLLEHSGKFLLNKPEYKELMEKMVQLIKDKKNDRQLNMNMKSALENIITLLYPPSVKSLNVTVKTITPEQQFYRILIRSELSSLDFKHIVKLVRKAHWDDVAIQKVLFSLFSKPHKISYQNIPLLTKVLGGLYSYRRDFVIRCIDQVLENIERGLEINDYGQNMHRISNVRYLTEIFNFEMIKSDVLLDTIYHIIRFGHINNQPNPFYLNYSDPPDNYFRIQLVTTILLNINRTPAAFTKKCKLLLRFFEYYTFIKEQPLPKETEFRVSSTFKKYENIFGNTKFERSENLVESASRLESLLKSLNAIKSKDDRVKGSSASIHNGKESAVPIESITEDDEDEDDENDDGVDLLGEDEDAEISTPNTESAPGKHQAKQDESEDEDDEDDDEDDDDDDDDDDDDGEEGDEDDDEDDDDEDDDDEEEEDSDSDLEYGGDLDADRDIEMKRMYEEYERKLKDEEERKAEEELERQFQKMMQESIDARKSEKVVASKIPVISKPVSVQKPLLLKKSEEPSSSKETYEELSKPKKIAFTFLTKSGKKTQSRILQLPTDVKFVSDVLEEEEKLKTERNKIKKIVLKRSFD
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MDGVQLKVATQVENIKRFQEAIAKSGQLSRGMCGILSSFDDRLMKLERTILPVYHETGNLQRRQENIDKTLTLLEEVVSLYTVSQQAEPKIAKGPGDLKPFIEALEQIETALEYFERHSPHNPEAALLQSLFSTGASSLQTEFEALLARHSRPITPVAILDMVDADEAPAAQYEPLPPRVVEDLALMSAWLRKRNLTQHLDIYARLRSRNLQRSMQGLREHQKAGSGTSGSLAPPHGPGSSPQLGGRKSRVPRKLHEALMRGLRRGSEATPAEAPRDDLVDQEVDAYLTALTALCKLMQSERTLLQQVLGSADGKEPAALPLERVVLPALEATTAEGEALANRVKRCVARHDFVTVLCLFPVLQHVRALRRDYDALLAGPTGQPGTAAAARLPGLAVTLQTTLNKALEELVDSVKSDPEGKMPRDGTVHELTSNVMVVLEQLLGFVEAAGAVLAVWDLASFSQSRDPNRAALAQYVTRVLSALNLTLHNKSAKYEDTALQAVFRLNNLHYVLRALTRSGLLEVVEGYESSLGQQYLDQIRDQKRLYSQSWSRVLHYVLEVDRPLSPSAKLKDKDRQTIKDKFTGFNRELDELFRVQKAYAVPDVELRESLKRDNKEFVLPKYKLFYDKYTAVPFTKNPDKYLKYSPLDVSNLIDRFFDAAA
The following text describes a protein:
Function:
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
Subcellular Localization:
Cytoplasm.
Sequence:
MDLTSKSKLIEILRRNNIFLKKSLGQNFLIDKNILKKIIDALEISKEDNILEVGCGVGTLTLELAKKAKKVIGVEIDKRFKSILEELLKDYNNVEILFEDVLKLDLSRIINLPYKLVGNLPYYISGSFLGEYFQKGPYAHLMVIMLQKEMAERLTSSPGSKKYSPLSILLHITYSYEIISKVSPSCFFPAPEVESVVLKLKFNPKLDKIYNKEFFFKLIKESFNQRRKFLLNNLERAFPSIDWKYVFTELNIDGKIRAEELSPEGYITLSNKAFNLWKS
The following text describes a protein:
Function:
Cell wall formation.
Subcellular Localization:
Cytoplasm.
Sequence:
MRVALLMGGVSREREISLRSGERVKKALEKLGYEHTVFDVREDFLKKVDQLKSFDVVFNVLHGTFGEDGTLQAILDFLGIRYTGSDAFSSMICFDKLVTYRFLKGTVEIPDFVEIKEFMKTSPLGYPCVVKPRREGSSIGVFVCESDEEFQHALKEDLPRYGSVIVQKYIPGREMTVSILETEKGFEILPVLELRPKRRFYDYVAKYTKGETEFILPAPLNPSEERLVKEMALKAFVEAGCRGFGRVDGIFSDGRFYFLEINTVPGLTETSDLPASAKAGGIEFEELVEIILKSAFLKEGVRV
The following text describes a protein:
Function:
Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2). By binding to the F-box of FBXW7, prevents the assembly of FBXW7 into the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates. Plays a role in spermatogenesis.
Sequence:
MEDMKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPILQKHGITHVICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQTGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGNMQVATAQNG
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSTEEPPFSTSALSALDKPLHQLTEDDISQLTREDCRRYLKQKGALRDACSFRFLEAFFAFVFEFCLFDVRTGMRRPSWNKSQAIQQVIMLKALLEPAPESGDGSRKLYITSRQQQTPTTRVQNGTSADTEISLSAEESVPGHRNDTEKSDFLGDNDSAPPGIGGVIEEAKGQMTIFYSGKVNVYDDIPADKARALLQLAASPLQFPHEDPVDGNMLQQPQNINLPILQTVRTTDNYRLNKEESSISREEISAEGSASRKASVQRYLEKRKDRFKSKRKGGGTFDVYINSQQINEQSSRSTTCSPPPVRPPNTPNRFS
The following text describes a protein:
Function:
Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MFCAISGEAVREPVISRVSGNVFERRLVEQLVQENGKDPITQQEMSVDDLIPVKASKIVQPRPPSATSLPALLSLFQEEWDSVAIEQFRLRQTLSETRQELSSTLYKLDAAYRVISRLEKERDEAREALYKFSESLGGRTAVAGTPVGMQVDTEAAAAAASIAQTGGISKDNLRSIVEHSLRELTQARKKRKFGKTWVTADAVKTLLAASTQNLHNFPKSEQEQPVSDILPNGAHPEIVLVRRGQNVSCLNLSTASVMCHFEPKAAACAWFGETQVLVAALDESAVYVFDLKESETPVIPKLTVALPRNIRCVAGHPSGAFFAAASDNECYICSNEGPLYTVQPESVVRAIAFHPDGHLLAVGGENGKLEFYLSASGELATTLGPQAGSISQLNFAENGYWLATTDTTDNISIWDLRKAVVAHTLKASSVPVNIAFNLSSRLIAASTSAGVDVFRYEKPSKSWSLDGTDATKSALSVCWIDAEQALLCGSKDGSLSLRKA
The following text describes a protein:
Function:
Acts as a modulator of macrophage activation through control of glucose metabolism.
Subcellular Localization:
Cytoplasm.
Sequence:
MEATPAAAASAVIPPSPLPSASVRASGSAGLSAGANAIRITSSGEATAASEDSVGRRIHQRANYSVRKKRELIALAQVAGVREVCRMEGVPRRTLRHWLDDAEKINSFEGPDSRTSIGRSGRREILPFGREMSDFLEEGQREGRELTSSHMIEYIRQSHSQWLQSYMVDKKSAESGQAALARLCQRFAERHGFTQSASGATRAATATTNSSTGAASSSPPVVHAKMSSNEPVAQPALAETSEPQPTYVVEAQDDSPLLFGLDIGTTAVKCVVVKADGGETVAVANVSLNDVIVPTRPGEDAVENTVGVQNVDQVLLAVQRAVTLLPEAARRRVTSVGICGQMHGIVWWCSRAVHDAAERLLATGGNWEQEDDDTYEPMWSELITWQDQRCTPSFLDDCRKKIARTNATANAPLPSRIAAGYGLASFAHTLENSPRTLVGMDACGTIHDFVAFILCGHTLPSETFMDTTDAHSWGGFNLQTHNWDSRVLRALRIPSSMLPAVKKPGTCIGHSSTGHSGFGLPLNKPVFVPMGDHPCSVLAALAQRQSDPGSDANLTLVNIGTSAQMAMVLTGGDVAKLSSEPSSGSADTQENSSFEVRPFLFEDRFLGVAASLSGGNTFAWLVRQWQQWGMEMGVTPAFNDGDEEQAAQREAEVYARLISLGFQCQDTELTFVPTLNGERADPNATGSILNLRMNNWGMGDISAALSRGLVENLFAMIPTELQPLLPVQPMIGTGNALVRNQLLQHYLLRRLTQPSQLQLQTAADAAVGAALTPSLVGVVLKV
The following text describes a protein:
Function:
May be required for ribosome biogenesis.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MIKIKRKTAPPPVEQDSDSDSSFDEEEPQDLEVQEGPVTDSSDEEAASSSKKTAKQGEASEDLKEEDDDDDEEENDDDDEEEDDDDDDDKKTRIPVLNPLSWMRNKEQRLALYKKMKKEKHKKKMQERRARRKAGVPANPGHTIESLREKDQTEVANLNDSDNEELQKELQLDDFSSYFERSYEPKVLITFADNPVTKTRKFGLELSRIFPNALVKIRNKSSVKKICKSAEREEFTDVVIVNEDRRKPNGLLVIHLPNGPTAHFKLSNVKLTSDIKRDHKEITKHRPEVILNNFTTRLGLTVGRMLGALFHHDPEFRGRRAVTFHNQRDYIFFRHHRYEFTKEGKRVKLRELGPRFTLKLRSLQEGTFDSKTGDYAWIISNKRHAMESRRRFFL
The following text describes a protein:
Function:
Inositol phosphate kinase with both monophosphoinositol and diphosphoinositol polyphosphate synthase activities. Able to phosphorylate inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) on both the carbon-3 and carbon-6 positions to synthesize inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4) and inositol 1,4,5,6-tetrakisphosphate (Ins(1,4,5,6)P4), and then to subsequently phosphorylate and convert either isomer of InsP4 to inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5). Its predominant in vivo catalytic function is to convert Ins(1,4,5)P3 to Ins(1,4,5,6)P4 to Ins(1,3,4,5,6)P5 via 6- and 3-kinase activities. It can also use Ins(1,3,4,5,6)P5 as a substrate and act as a diphosphoinositol polyphosphate synthase to generate two different isomers of PP-InsP4. Also has a role in transcription regulation. Forms a complex with ARG80, ARG81 and MCM1 (ArgR-MCM1), which coordinates the expression of arginine anabolic and catabolic genes in response to arginine. Recruits ARG80 and MCM21 to stabilize them. Neither the kinase activity nor inositol phosphates are required for the formation of ArgR-MCM1 transcriptional complexes on DNA promoter elements and the control of arginine metabolism. In contrast, only the catalytic activity is required for PHO gene repression by phosphate and for NCR gene activation in response to nitrogen availability, indicating a role for inositol pyrophosphates in these controls. Inositol polyphosphates may be involved in the regulation of chromatin remodeling of transcription. Regulates nuclear mRNA export via inositol phosphate metabolism. Also has lipid kinase activity, transforming the lipid inositol phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) into phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) in the nucleus. Its kinase activity is necessary for the propagation of most [PSI+] prion variants.
Miscellaneous:
MISCELLANEOUS: The expression of this protein is not effected by the presence of arginine; MISCELLANEOUS: Present with 2720 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MDTVNNYRVLEHKAAGHDGTLTDGDGLLIFKPAFPQELEFYKAIQVRDVSRRKSSADGDAPLCSWMPTYLGVLNEGAKIEQSGDAALLKIDERLSDSTDNLDSIPVKSEKSKQYLVLENLLYGFSKPNILDIKLGKTLYDSKASLEKRERMKRVSETTTSGSLGFRICGMKIQKNPSVLNQLSLEYYEEEADSDYIFINKLYGRSRTDQNVSDAIELYFNNPHLSDARKHQLKKTFLKRLQLFYNTMLEEEVRMISSSLLFIYEGDPERWELLNDVDKLMRDDFIDDDDDDDDNDDDDDDDAEGSSEGPKDKKTTGSLSSMSLIDFAHSEITPGKGYDENVIEGVETLLDIFMKF
The following text describes a protein:
Function:
Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNESYRCQAATWVERGSSATMGGVLFSAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTHLLGKCLISPMVLAAYAQNRSLKELLPASGNQLCEAFAFLMSFFGLASTLQLLAMALECWLSLGHPFFYQRHITARRGVLVAPVAGAFSLAFCALPFAGFGKFVQYCPGTWCFIQMIHKKRSFSVIGFSVLYSSLMALLVLATVVCNLGAMSNLYAMHRRQRHHPRRCSRDRAQSGSDYRHGSPNPLEELDHFVLLALTTVLFTMCSLPLIYRAYYGAFKLVDRADGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKAFTRPLIYRNWCSHSWQTNMESTL
The following text describes a protein:
Function:
Regulates arginine biosynthesis genes.
Subcellular Localization:
Cytoplasm.
Sequence:
MKKKVTIDEALKEILRLEGAATQEELCAKLLAQGFATTQSSVSRWLRKIQAVKVAGERGARYSLPSSTEKTTTRHLVLSIRHNASLIVIRTVPGSASWIAALLDQGLKDEILGTLAGDDTIFVTPIDEGRLPLLMVSIANLLQVFLD
The following text describes a protein:
Function:
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MANFKLFLALAACLSGQALAAPTKTIGKRAAITDVAHGYASQNGGTTGGAGGTTTTVSSYAQFTEAVSSDDAKIVIVDGTITETADQVKVGSNTSIIGKDANAILEGFGLLVKEKENVIIRNLGVKKVLADNGDAIGVQYSNNVWIDHCDVSSDRDHDKDYYDGLIDLTHAADYVTVSNTFVHDHWKAMLFGHSDSNGDEDTGHLRITVNNNYLNNLNSRGPSFRFGTGHLYNNYYLDVSDGINTRQGAQLLVEGNVWSGGKKPLYSTDDGYAVARDNDFGDGENTAPEGTLTSVPYEYDLLAASAVKDAVVGTAGQTLTF
The following text describes a protein:
Function:
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MGSKRSVSSRHHSLSSYEIMFATLFAILVVLCAGLIAVSWLTIKESQRGAALGQSHEVRGTFKITSGVTYNPNLQDKLSADFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVTFELFFAQWVSDENVKEELIQGVEANKSSQLVTFHIDLNSVDILGKLTTTSHLATPGNVSVECPPGSSPCADTLTCIKSDLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSESSVVCQWIIRVNQGLSIKLSFDHFNIYYTDTLNIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNVTYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFPPFTGPNFDHTFGNASGFYISTPTGPGGRKEHVGLLSLHLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGENWNYGQVTLNETVKFKVGFHAFKNKILSDIALDDISLTHGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSMNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGGEADSLFLTVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCMEDNFQCKNGECVPLANLCDGHLHCEDGSDEADCVRLFNGTTNNNGLVQFRIQSLWHTACAENWTTHISNDVCQLLGLGSGNSSMPIFSTNGGPFVKLNTAPDGSLILTPSQQCLQDSLIRLRCNHKSCGKKLVAQDITPKIVGGSNAEEGAWPWVVGLYYGGRLLCGAALVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMTSNLNSPQTVSLLIDQIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPAGRNCSIAGWGTVVYQGNTANILQEADVPLLSNEKCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVPRFTEWIQSFLH
The following text describes a protein:
Function:
May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
Subcellular Localization:
Cytoplasm.
Sequence:
MNYKIYIIEDDLSISLLLKDYITKYGFDVKIAENFENIIEDFNEFNPDVVLLDVNLPKYDGFYWCRRIRQKSKIPIIFISARDSGMDQVMALENGADDYIIKPFYCDVIMAKIKSHIRRAFGEYAPKVDEKIVELQGLKFYKERSEIEFKDERVIITKKEGILLEYLMKKYPKVVNRDFLLEKIWDDIEFVEENTLNVNVSRIRKRLHKLGIEDGIETVRGVGYRLNKTW