lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Sequence:
MAILYSEALRLIQAEAQRHRNAFLADGEHVPIGQARDRISRETVTSTISTPKFDTSAMDGYALSSSATQDATIDHPVTFEVKGMIAAGDEPLWIAADEQSGTPVCVEIMTGAPFPTGVGGNELDCCVRNEDVAVTVDETSNRRYIRVVKPAKTQQNRRFAGSDFKKSDILVDAGEVIHPGHILSMASVGMTQIAVTRKPRVAVVSTGSELLPPGLDQSPLHRISDANGPYLTATLESWGATVDFLGIIQDHAEDLEQALRLTLGQKAYDVIITSGAVSAGRCDLIRRLNARVVFHKVAMRPGHPVLFAQIPDSSNTDGHLRRETAFFGLPGNPVASAACLRFLVLPYLKYLQLQRPDDPSSASLLLPDDAETATTKEHPVVSTFCGDMDVFRPALVRGSSGHVQVKLIQDHSPGKIRPFLHSNCWIHIHRGVSELKAGDIVDIYPSH
The following text describes a protein:
Function:
Negative regulator of the mitotic exit network (MEN), required for multiple cell cycle checkpoints. Acts in the daughter cell to inhibit the mitotic exit pathway once MEN has executed its function. Through its binding ability to TEM1, interferes with the TEM1-CDC5 association, required for CDC5 kinase activation and MEN activation. Required for daughter cell separation and chromosome stability. Involved in copper sensitivity.
Miscellaneous:
MISCELLANEOUS: Present with 2020 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MKLERVSSNGSFKRGRDIQSLESPCTRPLKKMSPSPSFTSLKMEKPFKDIVRKYGGHLHQSSYNPGSSKVELVRPDLSLKTDQSFLQSSVQTTPNKKSCNEYLSTPEATPLKNTATENAWATSRVVSASSLSIVTPTEIKNILVDEFSELKLGQPLTAQHQRSHAVFEIPEIVENIIKMIVSLESANIPKERPCLRRNPQSYEHSLLMYKDEERAKKAWSAAQQLRDPPLVGHKEKKQGALFSCMMVNRLWLNVTRPFLFKSLHFKSVHNFKEFLRTSQETTQVMRPSHFILHKLHQVTQPDIERLSRMECQNLKWLEFYVCPRITPPLSWFDNLHKLEKLIIPGNKNIDDNFLLRLSQSIPNLKHLVLRACDNVSDSGVVCIALNCPKLKTFNIGRHRRGNLITSVSLVALGKYTQVETVGFAGCDVDDAGIWEFARLNGKNVERLSLNSCRLLTDYSLPILFALNSFPNLAVLEIRNLDKITDVRHFVKYNLWKKSLDAPILIEACERITKLIDQEENRVKRINSLVALKDMTAWVNADDEIENNVD
The following text describes a protein:
Function:
Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Functions in protein retrieval from the endocytic pathway. Required for proper sorting of the v-SNARE protein SNC1.
Miscellaneous:
MISCELLANEOUS: Present with 358 molecules/cell in log phase SD medium.
Subcellular Localization:
Endosome membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein.
Domain:
The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization of ATG20 to the perivacuolar punctate structures.
Sequence:
MSDLNDVQENAKLNSETRNTGKAEPPHGTTEYVAEAEISKNGVGSPKKSPKKGKVGKGDNNKVETELVHTALLEKDNPFMEEGPTGFTKSALLEIPGMRSHNLKNPNEDYEDDSEGLLPLNQESNAETCRTSLSGSINSMNGETSASEEPSVSNRKKSARIHILEAKRVSEGQGRAYIAYVIQFENSTVQRRYSDFESLRSILIRLFPMTLIPPIPEKQSIKNYGKSITGSSSKYLLPSEGSGSVDLSLSVIHASVNNSDEKLIRHRIRMLTEFLNKLLTNEEITKTSIITDFLDPNNHNWHEFVNSSSTFSSLPKSILQCNPLDPTNTTRIHAMLPIPGSSSQLLLNKESNDKKMDKERSKSFTNIEQDYKQYENLLDNGIYKYNRRTTKTYHDLKSDYNEIGEVFAQFAHEQAQVGELAEQLSYLSNAFSGSSISLEKLVGRLYYNINEPLNESVHMATSARELIKYRKLKYLQNEMIKKSLNSKRAQLEKLEAQNNEYKDVDKIIDNEMSKSHTINLERPNNNTGSGGKSYGGKLFNGFNKLASMVKDSVKYQETDPHTASINLKKEIEQLSESLEVTENDLEVISKVIKNDQLPKFSKEREVDLSEILKHYSRYMRNYARQNLEIWKEVKRHQDFA
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MLSAYFPVFVFILIGLAAGVLFILLGTILGPKRHYAEKDAPYECGFEAFENARMKFDVRYYLVAILFILFDLEVAFMLPWAVVFKDLGAYGFWSMLVFIVVLTVGFVYEWKKGALEWE
The following text describes a protein:
Function:
Hormone that acts as a ligand for natriuretic peptide receptor NPR3/NPR-C and promotes bone growth and physical endurance in muscle. Acts as a regulator of osteoblast differentiation and bone growth by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production. Required to enhance physical endurance: induced following physical exercise in muscle and promotes cGMP production, probably by interacting with NPR3/NPR-C. May act as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle.
Subcellular Localization:
Secreted.
Sequence:
MLDWRLASAHFLLAMILMLWGSGKAFSVDLASEASEFGAESLQSPPTTREEKSATELAAKLLLLDDLVSLENDVFETKKKRSFSGFGSPLDRLSAGSVEHRGKQRRVVDHSKKRFGIPMDRIGRNRLSSSRG
The following text describes a protein:
Function:
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
Sequence:
MELPKEMEEYFSMLQREIDKAYEIAKKARAQGKDPSLDVEIPQASDMAGRVESLVGPPGVAERIRELVKEYGKEIAALKIVDEIIDGKFGDLGSKEKYAEQAVRTALAILTEGVVSAPIEGIASVKIKRNTWSDNSEYLALYYAGPIRSSGGTAQALSVLVGDYVRRKLGLDRFKPSEKHIERMVEEVDLYHRTVSRLQYHPSPEEVRLAMRNIPIEITGEATDEVEVSHRDIPGVETNQLRGGAILVLAEGVLQKAKKLVKYIDKMGIEGWEWLKEFVEAKEKGEEIEEEGSAESTVEETKVEVDMGFYYSLYQKFKSEIAPNDKYAKEIIGGRPLFSDPSRNGGFRLRYGRSRVSGFATWGINPATMILVDEFLAIGTQLKTERPGKGAVVTPVTTIEGPIVKLKDGSVVKVDDYKLALKIRDEVEEILYLGDAVIAFGDFVENNQTLLPANYCEEWWILEFTKALNEIYEVELKPFEVNSSEDLEEAADYLEVDIEFLKELLKDPLRTKPPVELAIHFSEILGIPLHPYYTLYWNSVKPEQVEKLWRVLKEHAHIDWDNFRGIKFARRIVIPLEKLRDSKRALELLGLPHKVEGKNVIVDYPWAAALLTPLGNLEWEFRAKPLHTTIDIINENNEIKLRDRGISWIGARMGRPEKAKERKMKPPVQVLFPIGLAGGSSRDIKKAAEEGKVAEVEIALFKCPKCGHVGPEHICPNCGTRKELIWVCPRCNAEYPESQASGYNYTCPKCNVKLKPYAKRKIKPSELLKRAMDNVKVYGIDKLKGVMGMTSGWKMPEPLEKGLLRAKNDVYVFKDGTIRFDATDAPITHFRPREIGVSVEKLRELGYTHDFEGNPLVSEDQIVELKPQDIILSKEAGKYLLKVAKFVDDLLEKFYGLPRFYNAEKMEDLIGHLVIGLAPHTSAGIVGRIIGFVDALVGYAHPYFHAAKRRNCFPGDTRILVQINGTPQRVTLKELYELFDEEHYESMVYVRKKPKVDIKVYSFNPEEGKVVLTDIEEVIKAPATDHLIRFELELGSSFETTVDHPVLVYENGKFVEKRAFEVREGNIIIIIDESTLEPLKVAVKKIEFIEPPEDFVFSLNAKKYHTVIINENIVTHQCDGDEDAVMLLLDALLNFSRYYLPEKRGGKMDAPLVITTRLDPREVDSEVHNMDIVRYYPLEFYEATYELKSPKELVGVIERVEDRLGKPEMYYGLKFTHDTDDIALGPKMSLYKQLGDMEEKVKRQLDVARRIRAVDEHKVAETILNSHLIPDLRGNLRSFTRQEFRCVKCNTKFRRPPLDGKCPICGGKIVLTVSKGAIEKYLGTAKMLVTEYKVKNYTRQRICLTERDIDSLFETVFPETQLTLLVNPNDICQRIIMERTGGSKKSGLLENFANGYNKGKKEEMPKKQRKKEQEKSKKRKVISLDDFFSRK
The following text describes a protein:
Function:
Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis (By similarity). Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane.
Sequence:
MRLLERARKEWFMVGIVVAIGAAKLEPSVGVNGGPLKPEITVSYIAVATIFFNSGLSLKTEELTSALVHLRLHLFIQIFTLAFFPAAIWLFLQLLSVTSINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVVTPVLLLLFLGSSSSVPFTSIFSQLFMTVVVPLVIGQIVRRYIKDWLERKKPPFGVVSSSVLLMIIYTTFCDTFSNPNIDLDKFSLILILFIIVSVQLSFMLLTFIFSTRNNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRPTV
The following text describes a protein:
Function:
May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSACVKLAAYDFFLVAAIRSAVQILLLQSAIIKQQKDLSSGCKRPQVYFVLGRTIAGTVSVCCQFYAYQNMNIGDASAIIFSSPFITGILAAILLKERFTVFNLLATLVSFGGIILVARPPFIFRSQADDAPFRFAAASIAFAASIATSIAILNIRKIGNKVDSYVITYYFSIVCFIVPIIIFSITTSYRLPQCGATRWLLIAVGVLGFLGQISFTNAIQLEKATLISIIRTTDVIFGYILELIIFGSSPSLLSIFGSLLIIAGASALALKKWYDIKSDRKDCNQSKTTEQSINQHQDFTETHL
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSRKCRKRPSTTGSPSRYRGERRNRIAVRRQTRQSRSFRGDEPTSPVRSPQSSYVTIAGSAFSCSDDDESSELSDFDVINDVIQDALLESSDSSDYDDDDGNMSILQELRPFLFCSLYTVEDRRRRSRKEVTAPPVRRVSTRRSQGKRKGVLLPQGGGPPGAPLCFVVDLDETLVAARGGCAHLRPHLKELFDVCHEEGCEVVVWSAGTASHVNELVQAITTVVQRRAWYHHIISRHHRWFKEDCGGVKDLSLLGRPLDRVLCLENNPLSVHRQPRHSILVEDYVQPANSDDTLRFVAGVLRRIASRLRSAGERGGDVAQLLSVDSGLVELVIPINPQLSVTDPLVNNLYSIHSRGLRYSPQSVFTQRCYGGQRPFPASGS
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MNEPSACSGPPVKSKSSKNEPFYTLKALLPPYSEIQGNHDLLMSYELGPVEGGFSGSRRVKEKISSFLPHIIGEFHLDATKEASSLRALIEKPPIHKEISNLTSSSMQGFKLSAGPVDERYRHLFERRKEEPNLAYSEKLNLIRVRQQYDAYGFDDDETEKGFPKKHKKKKKDKKRKKEKEELGDAEKRKRAADEPMEF
The following text describes a protein:
Function:
Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNPAQTIAQQFLQQYYQTLMTNKMGLIQFYTDASHMTYGGQQHDGLKQINEKLESLAFQKIVYKIDDMDVQPGALENSLFIFVTGQLQMDDAETYKFSQSFQILPNGQGGLYVHNDIFRLVY
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MVGAQHSDVLRSLGLVSRASRRHVALPLSWNTLLKHGKGKDLAMMLTLLGAGSMGAFIAMRYAFKTPVALTFSWTDNKKASADVKNKADPELTIAGLQNMGNNCFLNVVLQALASSDVLVSFMEECAGVIDTQGVQAERTTMPLAAAVADLLRELAQGQIARRILSPRKVMLALNLYSRQFDLSMQQDAAEALAYLAAGLQEERDKYLNLHRPVSQSFGSVLDMNLATPQLDQSLLHWPLEGTLGSLMTCQRCDFQFSTVFQYFNDISLPLSRRTDGSIIDNCTLEDCLDRFTAPEWVASVKCSHCAHMEASKVLRSQMDNTDLTTDQEQLDVHIIQEKIKIIEDCSCDDDCSCEALVLKQGGVWNSVRTNASKRLRIGRSPEVLCLQVQRAVVNEVGELRKLSGHVRFPMILDLFPYTVASQENKVRMIDTRTEDHGKSSIRMLGQRGVVFSHIRKLQGPGYSSLLFPLERGIKGGSKSSTQTDDVLSTTESADARVTTEDVVTDTVSDESLVLEDSLADLAAMNNQAITKNKEARDLTHQETPNSDGTSMVDISDASSSETITSSTPGCSGLDRHSIQVSGSIRPQNAQAERTLTSRKLLYELLSIVVHHGGPHSGHYTVYRKVRLPKSRDSKVKSAEEDCAGLLCHTEVREHSEKVEIDATVTSRVLEQLQDGRERLREATEEGNARDEEIVLWFKVSDSNVRRVEELEVLLANASLLFYERLTNS
The following text describes a protein:
Function:
Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.
Sequence:
MSSRRRVVVTGIGMINPMGWDVATVWSGLQESGSGVAPTTLFNASGFPTRISAEIKNWDITKAVEDGEKHVQRGRHTQFAIAAATQAMKDSGVLSSIKDPTRIGVYLGSGEGNQDFNTFSKMMVAALADGTYDPTKFIAAGLSLLDPAKELEQEPNMPAAHLAARFNAQGPNFNCLTACAASSQAVGEATEIIRRGEADAMLAGGTHSMIHPFGVTGFNLLTALSESNDDPTKASRPFDAGRNGFVLGEGSAMVVLEELESAKKRGATIYGEVAGYGTTADAYRITDIPPDGHGGIGSMRMAIADAGLNPSDIGYVNAHGTSTKVNDRVETKACREVFGEHAEQTPVSSTKSMMGHLIAAAGVTEMIVCLMAIRDSVLPPTINQETPDPDCDLDYVPNEARPAEIKHALNNSFGFGGQNVTLCLSRFDG
The following text describes a protein:
Function:
Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moieties to galactomannans and their subsequent pyruvylation.
Sequence:
MFANINIRKSVWLFLLAAVSCTLFIYGVTRTDLQTLKNPSSLTSPSSSTSVDKKKPLFTKSPRNSASCESTITLQSNLLFTYYKHYFAGIKKVALIGFPDHPNKGDSAIYVAEKKLLDALNIEVVYITAQEADYSASELKSIISDIPRDEFALAFHGGGNFGDLYPDHQHLRELVVRDFPSFTTISFPQSVWYNEQQLLEQASILYAENPNITLVTRDRQSYGFAVDAFGKHNEVLLTPDIVFFMGPIPEIREATPITHDVLILARLDHEGGQQHGAEDYYRDTLNAANLTYSVEDWLLWDPPVAQNPDSSFDDRGQARYEAGAEFLASARVVITDRLHAHILSTLMGIPHIVVENSQMGKITNYHNTWLHGCTLDGVSVVVDSVDKALSLLLEWNEAGYF
The following text describes a protein:
Function:
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
Sequence:
MDLVGVNYGRLASNPLPHDVAIRKIKDVGANAIKLFDSDSATLDALLNSGLVVMTAIPNRELHKYAYDPAAAPAYVSFIKRYIERNVLIQYVAVGNEITASWFGGQFEPLIMPALINIQKALDAGGLRNRVKLVVPLDLSILSVSYPPSAGEFRPELTGLMKDLLYFFRHNGGCPFVINIYPQITKIENPGIPLDFVLLEGQQHGYWDDGKFYKNLLEAQLDAVYHAIRKVGYETDNLMLGEIGFATGGAEVATFENARRFLRNFVNRRRDGTPLIRKSIPAFLFAFIDEDLKDTCGGHSNVDSGHCGFLGHYGKDVAAVSEDLWADGLACGACFQLECINSTACHAGVKRTVTVTDSCIGCGGFTDKGIEPGQHFDLSRTAFTAIADESAGFIQVKARRVACSGLSTSVYVRGTEWWLEVRFMGLPGEAGNAEHVTITDPQGIVRDLAKSWGGAFETIGQRLEAPLSLTVVDGFNSTWSFPNAIPRGWTSDRAFETQTEASPRGRELFAAGGVECAKNVAFQASGPRGGRELVEQREDYRVPEAEKEREILNDFRECHMPYQAARNAKFECLQLSKKMSTIFLEVGKLKEDAVGATASPTYSTSLGRAIRKPACRGWTSLDTLDSRTDRPKFFVYLGEGCFLTIVIPTMAPKKSSDYVVLSHTEHVRLRPDTYLGRTTPETATLYVADGPSSIRLRSVSDFVPGLYKIFDEVLVNCIDQSKVDDSLTKIKVSIDQEAGKVTVYNDGRGIPVEKHPSMTDCFTPEVIFGVLLPGSNYDDSVERVVGGRNGLGVKLTNIFSTLFELEVVDSERSLKLTQKWNKMQRKGEPKVTRLRENHKTASYVKVAFVPDLSYFGVERLSDALVAFFHKRVLDAAACTPERVGVYLDGKKVGVKSFNDYVSMYIGRPSESPRVEIDAGPRWKVVLARAPTTEDAEEYRSGDLQVSFVNGVLTAGGGTHVEHVMSLFLKQALSLLDAKAGSGVAGALRSALLLFVDATLVNPTFDSQTKVRRRAAGSLLPPTRAL
The following text describes a protein:
Function:
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Located at the polypeptide exit tunnel on the outside of the subunit.
Sequence:
MSEQPHKQRTRTKRASLHEKQDQVRATLSEELREEYGQRNVRVNVGDTVEVMRGDDAGEDGEVTDVDLRDAEVFVEGVTVEAADGEETPRPVESSNLRVTDLDLDDDMRVERLEGDNE
The following text describes a protein:
Function:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase.
Miscellaneous:
MISCELLANEOUS: Present with 9890 molecules/cell in log phase SD medium.
Sequence:
MPSLAELTKSLSIAFENGDYAACEKLLPPIKIELIKNNLLIPDLSIQNDIYLNDLMITKRILEVGALASIQTFNFDSFENYFNQLKPYYFSNNHKLSESDKKSKLISLYLLNLLSQNNTTKFHSELQYLDKHIKNLEDDSLLSYPIKLDRWLMEGSYQKAWDLLQSGSQNISEFDSFTDILKSAIRDEIAKNTELSYDFLPLSNIKALLFFNNEKETEKFALERNWPIVNSKVYFNNQSKEKADYEDEMMHEEDQKTNIIEKAMDYAISIENIV
The following text describes a protein:
Function:
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Subcellular Localization:
Nucleus.
Sequence:
MDKESKVIILPKTNSSSEFKIINLPNPTNLTTTKSYLLHHNEDSNNQLYELNIIGGEDDNDGNDDEKTDNGNAGTKNKGQKPKSKLKSENSIKSLIFEPGYVLQSPKIIISNKFNLSYLLISLFSNINQQKSQQQSQQSSLSSENLFNDNFKSLEDLKDQLLNEYREDTNNNDWVLEIPDQLYHQSLINLCDVITENIDESFYRFDLSKILHWLNEKVLALQKYILTNDNSILTKLKLELNPSMSNNNIEDQLLNDLGLLYSIDYIFNSYLDDGVNSFLRQKLLEEFKYDFTRVLKHIDDLKIQQSLIENVLESNLKSTTNNTKSSSTKKKPATGTTNKKVKRGAIDSFFKKAK
The following text describes a protein:
Function:
Co-assembles with BUD4 at bud sites. BUD4 and BUD3 may cooperate to recognize a spatial landmark (the neck filaments) during mitosis and they subsequently become a landmark for establishing the axial budding pattern in G1.
Sequence:
MEKDLSSLYSEKKDKENDETLFNIKLSKSVVETTPLNGHSLFDDDKSLSDWTDNVFTQSVFYHGSDDLIWGKFFVCVYKSPNSNKLNAIIFDKLGTSCFESVDISSNSQYYPAIENLSPSDQESNVKKCIAVILLQRYPLLSPSDLSQILSNKSENCDYDPPYAGDLASSCQLITAVPPEDLGKRFFTSGLLQNRFVSSTLLDVIYENNESTIELNNRLVFHLGEQLEQLFNPVTEYSPEQTEYGYKAPEDELPTESDDDLVKAICNELLQLQTNFTFNLVEFLQKFLIALRVRVLNEEINGLSTTKLNRLFPPTIDEVTRINCIFLDSLKTAIPYGSLEVLKACSITIPYFYKAYTRHEAATKNFSKDIKLFIRHFSNVIPEREVYTEMKIESIIKGPQEKLLKLKLIIERLWKSKKWRPKNQEMAKKCYNNIIDVIDSFGKLDSPLHSYSTRVFTPSGKILTELAKCWPVELQYKWLKRRVVGVYDVVDLNDENKRNLLVIFSDYVVFINILEAESYYTSDGSNRPLISDILMNSLINEVPLPSKIPKLKVERHCYIDEVLVSILDKSTLRFDRLKGKDSFSMVCKLSSAFISSSSVADLITKARILEKDTAFHLFKASRSHFTLYSTAHELCAYDSEKIKSKFALFLNIPPSKEILEVNNLHLAFFARFCSNDGRDNIVILDVLTKHDDKHIEVTSDNIVFTIINQLAIEIPICFSSLNSSMAKDLLCVNENLIKNLEHQLEEVKHPSTDEHRAVNSKLSGASDFDATHEKKRSYGTITTFRSYTSDLKDSPSGDNSNVTKETKEILPVKPTKKSSKKPREIQKKTKTNASKAEHIEKKKPNKGKGFFGVLKNVFGSKSKSKPSPVQRVPKKISQRHPKSPVKKPMTSEKKSSPKRAVVSSPKIKKKSTSFSTKESQTAKSSLRAVEFKSDDLIGKPPDVGNGAHPQENTRISSVVRDTKYVSYNPSQPVTENTSNEKNVEPKADQSTKQDNISNFADVEVSASSYPEKLDAETDDQIIGKATNSSSVHGNKELPDLAEVTTANRVSTTSAGDQRIDTQSEFLRAADVENLSDDDEHRQNESRVFNDDLFGDFIPKHYRNKQENINSSSNLFPEGKVPQEKGVSNENTNISLKTNEDASTLTQKLSPQASKVLTENSNELKDTNNEGKDAKDIKLGDDYSDKETAKEITKPKNFVEGITERKEIFPTIPRLAPPASKINFQRSPSYIELFQGMRVVLDKHDAHYNWKRLASQVSLSEGLKVNTEEDAAIINKSQDDAKAERMTQISEVIEYEMQQPIPTYLPKAHLDDSGIEKSDDKFFEIEEELKEELKGSKTGNEDVGNNNPSNSIPKIEKPPAFKVIRTSPVRIIGRTFEDTRKYENGSPSDISFTYDTHNNDEPDKRLMELKFPSQDEIPDDRFYTPAEEPTAEFPVEELPNTPRSINVTTSNNKSTDDKLSSGNIDQKPTELLDDLEFSSFNIAFGNTSMSTDNMKISSDLSSNKTVLGNAQKVQESPSGPLIYVLPQSSTKHEKEGFLRKKQKDEPIWVSPSKIDFADLSRRTKALTPERNTVPLKNNDSRKYKYTGEGSIGNMTNMLLTKDASYAYLKDFVALSDDEDEDGKQNCAVGGPEKLKFY
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDDEVYKQRLTALNNLRIVIFFDILIILLGYIGTWNLKTLQLVNPSLWSFSPSLWIYIRGTVLCADCIFTAGSANEYSAVQNSVFQVSSLMFYGLMMEFFGYSFDRVGCMELAFISFSAACYFNIRSIKSLSLKNKNWTIISIIEIPIKLHFILNVLLFLKFSEYMLPLLGRVHLSYHLFALWVINLYIWIKLIDSKDFVLGFLAGLSVLLLNTGSLITAKPLISYFNLLTSCLIIFPSIWIYAIEKKNFKNLSYEDDDYRNYW
The following text describes a protein:
Function:
Esterase that preferentially hydrolyzes short-chain fatty acids, particularly pNP-acetate (C2) and pNP-butyrate (C4). Also has weak activity with pNP-hexanoate (C6) and pNP-octanoate (C8). It can also hydrolyze short-chain tryglycerides such as triacetin and tributyrin. Important for intracellular survival.
Sequence:
MPRRSTIALATAGALASTGTAYLGARNLLVGQATHARTVIPKSFDAPPRADGVYTRGGGPVQRWRREVPFDVHLMIFGDSTATGYGCASAEEVPGVLIARGLAEQTGKRIRLSTKAIVGATSKGVCGQVDAMFVVGPPPDAAVIMIGANDITALNGIGPSAQRLADCVRRLRTRGAVVVVGTCPDLGVITAIPQPLRALAHTRGVRLARAQTAAVKAAGGVPVPLGHLLAPKFRAMPELMFSADRYHPSAPAYALAADLLFLALRDALTEKLDIPIHETPSRPGTATLEPGHTRHSMMSRLRRPRPARAVPTGG
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
Sequence:
MVENIGSGSAELVSYAKLNLYLDVLGKRSDGYHEIVGLFQTISLHDTLTVEICDRGFYLESSVALPSDNTIKRAWEMFRKNTGKEFGLKVTLKKEIPVGSGLGGGSSNAAAVLRYLGEVFKIPLEDLLNIAAQVGSDVPFFLYGGTALVRGRGEIVEKLEDIEGYSVDLFFPGIHSSTKEMYLSLTPEMYRKGPGRVEELHRAYLERNYEKIKELSYNVFEKVFLEKHPEVMDGLRNFGDGSIVKMMTGSGSVFFALYPLDKGNYSFVGGV
The following text describes a protein:
Function:
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). Does not show detectable N-acylamino acid racemase (NAAAR) activity with N-acetyl-S-methionine as substrate.
Sequence:
MIEIEKITLYHLSMNLKKPFKNSIETLQERKFLIVEAIDTSGVTGWGEVSAFSSPWYTEETIGTCLHMLKDFFIPNVVGREFNHPSEVPDSLARYKGNRMAKAGLESAVWDIYAKKKGVSLAEALGGTRDKVPAGVVVGLAPLDDMLKEIESYQKEGYQRIKIKIQPGQDVELVKAIRSRFPTIPLMADANSSYELKDISRLKELDDYHLMMIEQPLQADDIVDHRHLQKHLKTAICLDESICSVDDARRAIELGSCKIINIKPSRVGGLTEALKIHDLCKEHHMQVWCGGMLETGISRAQNVALASLPQFTIPGDISSSSRYWDEDIVTPDIRIDNGFISVSKQPGLGVEVNQDIMRKYVTKMDVFTQHG
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
Sequence:
MEFLVQKIGMSRTIDANSTPVTLLKVLQAKVCQLENGKALVAYAMHKKHNKAIEGQQKKYQLSKEFNHFATLKASQQKELGDLDLSALETLKRVKASFKTKGRGFAGVMKRWNFQGGPAAHGSRFHRRPGSIGNREWPGRVQKGRKMAGHYGNELVTCQNEVLSFDKESMVLVLKGSVAGFSGAYGRIRAV
The following text describes a protein:
Function:
Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd.
Sequence:
MKLVRPQKISDQVLSVLEERIAEGVYAEGGKIPPERVLAEEFGVSRPSVRSALNVLVARQVLEARQGDGYYVSVKPQQDFLQSWQELLGKHSNWEQDVFDFSCHIEGCMAALAAERRTDADLKRIGFWLEKFEEACESGNLEHQSEADVSFHQTIADAAHNLLFSHLSGGLLKMLYRQTRSSLIYLNQEEDPRPKLMAQHRVLYEAISNRRPGEASEAAKAHLNYVASSILKDREYQSRNRHADTLAQNDLKRVQDWAV
The following text describes a protein:
Function:
Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
Subcellular Localization:
Cytoplasm.
Sequence:
MARYDLVDRLNTTFRQMEQELAIFAAHLEQHKLLVARVFSLPEVKKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQVDNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQDIAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Sequence:
MIRRSSLIFTRSISTSFSLPVNKTLEILKATNANFEGLFTNNAINQLWFQRGQQLVQNLNQHLAQTNNGLLSDSNNINNNTSSTSDNGNGDGENVVNYSLNEIISITMNKPELFHIHKNATNLYNLQFFFENIRQLEQQPQEIIPSGSEVLLQTPKDQFKNVPSDKELVDWIEHSFGSIQELRNLIINSAKGIKGDGTVWLVAESTMSENYLSKSNFSSPLFHNLAIVNTYNGGMIDDSERSGQLRRMKSVLQQQQEQNEEEQDKSTENKQKHNNSTSEFELGSVEQAELETAFHNKRLVPALAIDVSPRNYLINYGAYGKQQYLENVWECIDWDIVSRRLPPRSKQVITV
The following text describes a protein:
Function:
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAETDAVNDDLLHQSIKRKKSSGKERQKAQAMVTSFLNNHLPPRYRISNENYLQVIQKSITLENKGITKIQKAKKKRCNITPYREKHREKLHCSLELSQRFDDYMPLHNLWVDYMSCLLNIQKRSTTSTCSLSKEYTQKLLKADYHGCWITVTRSRCPSYIGISGIVLQETKNALTLIAPSNKVKCIPKTNNIFTFKIGDLVFTLYGNQFRYRSTDRAARKFKLKSTIDL
The following text describes a protein:
Function:
Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.
Sequence:
MVILNFTLSEEGVSVFHDALACMYKFSDDVCLEARRDKLTLTTLNISKSAYVCFTFAANRFFSRYHFEGNAQYRDRFFCQLYIRSLLSIFRSRQGGDSARDKDASIERCDVAIDDGPGKKSRLIARISCRNGITASHSLPFESKPPTHAKFEKDEAGNRWSISSSTLRQLMDHFGPGIELLDINTDDDDHVVNFTCFTDKVQKRGPHGNEAVLKKPLHTNISVEMAEFNEVEVQDKLHIIISVKDFRAILQHAQIISGELATYYSEPGRPMKLSYSADGILCEFILMTVGEQDAITQKHKNTRARASKTPKPGSGPGPGPASKPDGSVANNEAKDVPKPAQKPPQQKTPPQPRQTQFEIRPPPIPPRSPVAARTDRSDSPLFVEQGDEDRQWDPVDREDEEEMDNARVEWNATGEPVLLRHFPLVARKKMANIHSRTRRPCELAVYWQDRLCPVMSQTDLLGDSSQPSSFLRHVSCCLLCLFFC
The following text describes a protein:
Function:
Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Cysteine protease with a preference for Met-1 and 'Lys-48' over 'Lys-63'-linked ubiquitin (UB) tetramers (e.g. Ub2, Ub3 and Ub4) as substrates.
Sequence:
MQNQIDMVKDEAEVAASISAIKGEEWGNCSSVEDQPSFQEEEAAKVPYVGDKEPLSSLAAEYQSGSPILLEKIKILDSQYIGIRRTRGDGNCFFRSFMFSYLEHILESQDRAEVDRIKVNVEKCRKTLQNLGYTDFTFEDFFALFLEQLDDILQGTEESISYDELVNRSRDQSVSDYIVMFFRFVTAGDIRTRADFFEPFITGLSNATVDQFCKSSVEPMGEESDHIHITALSDALGVAIRVVYLDRSSCDSGGVTVNHHDFVPVGITNEKDEEASAPFITLLYRPGHYDILYPKPSCKVSDNVGK
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MYTTKRFQQLLKEFEVALLLKFSKQLLLLGKIESYLNNGSSMKHEECKSQIYDCRMAVKIYVCSITANKSTNLKHFVRLFFLLGDSERVNLCIKRLIYTFIGSINSVIDKKEDIEQELYSSCMHCSIMSPKLQKVMLAQKSLILNKVFDYLFFLYGLSGTSILYTAGDHIRKLDFKDSGFITPFFQLLLLVLLFTLTFKSKHSLNAYSLTASQFSGHTVCNESSLKPNENSCDLNLSRTATIKLESAEDDACQRVLGLIKSYMRPRTLEELKLEFRFEHKSVQDITTCILDEVDGVQMARVLEINPDAPILAF