lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSLGGGGQQQLQQLSQEIQAIEEEVEELEADVASLRQEQTEIEEAKEALDVLETGATVQVPLGGDAYVRAEVKDMDEVVVSLGGGYAAEQDSDAAASVLDEKKATIDGRIDDVQAEIADLSEEAEQLEQQAQQAQQQMMQQQMQAQQQPQDGEQ
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
IAMPVGPAPVVTGISPKDGTPFTKVTIRGENLGTSQSDVLGVAICGKNCSMTVDWVSPSKIFCRTAAGIGKGDIIVITKSGGTGSSTVTFTGLPVKKVGPLETSAVWVDETEWVDQRLDRAQKSSNISLRTDPLGLNSEELGHKTQAYMQLADLFGKGSPDPTDQNFEPSWFLLERHCNTSFSKLKEGHAYMKRKANRNTNNAPLNHVKDSLPVFFEVHETLSGIHHKMQRDEGGRKNGNLTDKLESTLNEASENANKLFDTVLSCKDRADSIRNTLNVLQRFKFLFNLPLNIEKNIQRGDYGVVINDYEKAKSLFSETDVDVFKKVFAEVEKRIEKFREQLKQEVQELPSPLHRQKKLIRYLLGLGESGDPGWECLVHQHGWIQESMIKCKDRHIKTGEEHPKKHNVTPKATLIKSIVINYYYLLILYLLLLSAFKCTENLDEAGKVQVCHQYLEELTSIATSQIPEHWNLWQHYSTGVILSETGEKSSDVENLKEMASKHSKQMKGLLRDTVILFVNLLRAAFLPATLHVDDDEDLHERESYGVWPSEVPLPATVLYDCVRAARQCLIELSSLTLPHGTLQSLNDVIHDLRVLSLSTFLQEATDDIRGLRMKETWEVSNKGVTALPSQFHNITVALVSVVRDVLESLPGEEPVFARVAVQSRVTQDFTRLFTTFSSCLERCVFIEESESDSSKVPQESLPPLRKLVSPITPRMFLLQEQRLVIGISNLSYTKQNLLHPLIDHFRQLHFPNIEFFTQTCDSEFSKLDEKFFEAYVEHRVEPLTGALEPGMYAGSFDWNECLRPEGVRPYIKTALMSIITIHAEVYSINPDLVPRFLIQVIQMTSEEVLRLIQCIRKIGTNGSMQARLDIEALQQATAAFESTQSSTNFVEALDSIPDMSSAADRRFLDENINKFKSLLIFQLRCFS
The following text describes a protein:
Function:
The homodimer mediates transmembrane sugar transport down a concentration gradient. Transport is probably effected by rocking-type movements, where a cargo-binding cavity opens first on one and then on the other side of the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MENLIGYVAAFLTTVSFLPQVLRVVMTKQTRDISRNMYIMFFLGVVLWFVYGILRSDLPIILANVVTLFFVTIILYYKLTEGNQT
The following text describes a protein:
Function:
May be required for the assembly pathway of mitochondrial outer membrane proteins.
Subcellular Localization:
Mitochondrion outer membrane; Multi-pass membrane protein.
Domain:
Its C-terminal part seems to contain many membrane-spanning sided beta-sheets, that have the potential to adopt a transmembrane beta-barrel type structure.
Sequence:
MTEQFESTSFPSDIPAVNEESKLSAEETFKSLSEILAENSTLPVGISSIRVTGAHHTRPSFIRKVLKTCLDTSKPAKSRSLLETLNAIQETTGNLMAFNVYETANIKIDRASSSVSGDDDLDVTIQVKEKPRLYVETGTDVGNVEGNVHANVLARNVFGGAELLSGNVSYGTRNRSTMSVNFETPVNADPKTRLRFNGHSNLRDNKSISSHDLLTKGITLSLQHQDLWSGEHLLSQNLLWRQVTHLTEYASPSVRLEAGDSLKQSLSYTYTRDTRDHLMIPTKGDYVRQTLELAGFGFLPGDASFLKSEFWGQKAVALNSSRSVSLSLSARIGALHSLNKKQVSLCDRFMLGGSTSLRGFSEDRIGPKDGRDSLGGTAYMAFSMSLLFPLPKVDASKPFRLQLFANAGGLSNLTSPNPCGTYKSILSKPCISTGLGLVYATPAARFELNFTLPIATTEKDIGRKGLQFGAGIDFM
The following text describes a protein:
Function:
Transcription factor that contributes to plasma membrane sphingolipid incorporation and membrane permeability, decreasing fluconazole accumulation. Regulates 337 genes under fluconazole stress, including several related to lipid biosynthesis pathways such as RSB1, encoding a sphingoid long-chain base efflux transporter. Associates with the promoter of RSB1 in the region containing two 5'-CCCCTCC-3' motifs and increases its promoter occupancy upon fluconazole stress.
Subcellular Localization:
Nucleus.
Sequence:
MSTTTTIPGAAPKKKRNRIPLSCTICRKRKVKCDKTRPHCNQCTKTGVAHLCHYMEQNWAQDAKKEISKDNELKNLKERCKILEEKLARYMHNPAVTASLGASVVNSPVGLSSPVDAPIKLTNSPMVKLEDDTNMVDDMARPVKEHDYDELDLTRQFDLLHIKSNGTIHLGATHWLAIMKGDPYLKLLWTHIFTMREKLLEYYTNGSGHKRRKRQKNGGKCPIDHSKFKAAESEQKNHFVKTTPMVNDTPKSSIGKCPIDHRAMSNPVGVNSNAGQFQPMHPPHTHIVQNKCPVDHKVNDSNLTSANTDNKNAATKKCPINHSKYTKEKMQGAGLNDKPLTKQEVIEKLCQLLPPKRIIMLYIDKFFKHFYPVIPILDELNFKNNINQIFDLNSLISNTIMSTSSDLELEPITSMTLNKPTDYSNLGILIIIMRLVWLSLPMNSCKIDIENPLLNKLRTDHDFKNEDYESGSLASSLRLKDELQLLKYEVDGFALDLVKKHLIKFDEISSISNTNVNMSTIQFAVFFKFYLMNCANASSQGNSAGNFDNESHQILLSSIMMMAFSCGLHRDPDNFPQLNVVSANLTTDNTRSGPPSNSNRNGSETPSVSPKDTNVSIERAKHTWRKVWYYIVSLDVQQSLLLGSPRLIRNLNDISDTKLPSASKIDYVKDIKELIIIKNYTLFYQLDLCIVAVLNHTLNISIAKNVRKFELDALISNLQKLTDGEKGINDVINSLINHGLLSTSEVPIGLQKFDDIYDLPRMEDILLARKSEQEIVGDENERIGQDVDKKLDLPHEMTSKALFFSKHMTLRMLLYLLNYILFTHYEPLGAEDPTTTILAKNYAQKALDYALDGYRNCMLYFVGVSDQNPLFKYMNVILCFHSLDIGHRALQFIICLILRVKCGPLNGLKETQTIFGTSVPSSCNSSSVEDENTEEPNNLNQDNQFQDDLMQNINLDNSDSLAEKLMSRMVLFKQLTEKLAPKYSFSVRVMKSTGFFISLLTTPSGSFGSKKNGSKHKHGVGKLLLSNWKHPKISNIPALLSSDSDQLKKCPVYQDALGFMPSRPSVTNLPSISNVEGLLPNAQANGRMTPQLPPIRSYQPITYSSSHMRVTPNSESDARKLGPDSHQVTNPLIPSPLSPANQQQNQVNVLHMHQQRSMSPAPMPMMNPTAMTTNQNMIPERKYAPHSGAATPILPGTNSDIQQQTQMTRNDPYPTEQFSLPPISSAKNNMAWGTTPESEQGDHLTPNTTTSSLDTPDFEDFIIQNSNFNGLLINPNSLAEAMGSLPSGRDGAILNVNSFKDFTTSTNDKTITPNSADQTDLFSVDMASTDFLPIDNFAIDGFMDSANLDIGSIWE
The following text describes a protein:
Function:
May play a role in processing or organization of cuticle collagen proteins, including rol-6 and col-19.
Subcellular Localization:
Cytoplasmic vesicle. Secreted.
Domain:
The ShKT and Thr-rich domains are required for body morphogenesis.
Sequence:
MRYLCKSILLAVHTILLVGSVCCSTDVHNTDDKYALIHVSAHDEQSLHLIKQLQLNDFKYDLDFWKSPSSISDKADIMVKRGKSERMLRQILSFANVTVSMSVPDVEKLIMRNEGTTSKSHLGFGSLSKWLHDDPILDSEPDLDLTKVGALKKAKYPFGDYASYADMVKYMRTIEFYYPRIAKIVRIGATHEGKPIEGLKIGARSSHKKRAVWVDGNIHAREWASSHTALYFINQLVSEYGKDAQITNYVDTLDFYIVPCLNPDGYEYTRTSPIPTVRLWRKNRSPELCRPSLWGGEKCCRGVDLNRNFRFHWAERGSSYEPCSNIYHGEEVFSEPETRAVRNFLATPEMKDRVDAFVTLHSYAQLWIYPYSHEEQNYPEDIGELRKTARKAINRLSRVYGTNYRMGTGADTLSPAAGGSDDWAKSALNVKYVYLIELRPQMELSNGFILHKKELIPTAVETFEGFREVVDAVLTLNNSTSSIGLSSGSNTSRKTISDLQMRKQQYRMRLLASQAAGSTTRSTTTLKTSTTSVSTTSEATSPSKTSRHFDRFTADLNSSTRARPTPPMAPPIMSPSTEFSTTTTEEEDVTGVIRSSSIASRATTYGFFTATKPSAFLDPECRDMRYSCGFWLKNNKQVCEEQQSFMRAQCAYTCKFCTSFIKRH
The following text describes a protein:
Function:
Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and lymphocytes but not neutrophils.
Subcellular Localization:
Secreted.
Sequence:
MELPTAKWMLAAACFLLSVCGGSAAPTECYFNSRQCEFEGKHFLLGESWMDNSCMQCTCLHPVGVGCCELHRPVDFPAWCKVQIEPVSCKVFLVQTADPRLPCSPGEANHDPSHGSLHLQQQL
The following text describes a protein:
Function:
This protein is essential for differentiation. It may play a role in localizing of Nanos (a maternal determinant) activity in oocytes. Functions redundantly with BicDR. During oogenesis, plays a specific role, together with Rab6 but independently of Sec5, in the polarization of the oocyte microtubule cytoskeleton, in oskar mRNA localization and in the anterodorsal secretion of grk. Plays a role in the biogenesis of annulate lamellae containing nuclear pore complex components. During macrochaetae development, together with BicDR, involved in Rab 6 and Spn-F stability and distribution and actin cytoskeleton organization.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSSASNNGPSADQSVQDLQMEVERLTRELDQVSSASAQSAQYGLSLLEEKSALQQKCEELETLYDNTRHELDITQEALTKFQTSQKVTNKTGIEQEDALLNESAARETSLNLQIFDLENELKQLRHELERVRNERDRMLQENSDFGRDKSDSEADRLRLKSELKDLKFRETRMLSEYSELEEENISLQKQVSSLRSSQVEFEGAKHEIRRLTEEVELLNQQVDELANLKKIAEKQMEEALETLQGEREAKYALKKELDGHLNRESMYHISNLAYSIRSNMEDNASNNSDGEEENLALKRLEADLSTELKSPDGTKCDLFSEIHLNELKKLEKQLESMESEKTHLTANLREAQTSLDKSQNELQNFMSRLALLAAHVDALVQLKKQIDVKEQGKEGGQKKDELEQQLRALISQYANWFTLSAKEIDGLKTDIAELQKGLNYTDATTTLRNEVTNLKNKLLATEQKSLDLQSDVQTLTHISQNAGQSLGSARSTLVALSDDLAQLYHLVCTVNGETPTRVLLDHKTDDMSFENDSLTAIQSQFKSDVFIAKPQIVEDLQGLADSVEIKKYVDTVSDQIKYLKTAVEHTIDMNKHKIRSEGGDALEKVNTEEMEELQEQIVKLKSLLSVKREQIGTLRNVLKSNKQTAEVALTNLKSKYENEKIIVSDTMSKLRNELRLLKEDAATFSSLRAMFAARCEEYVTQVDDLNRQLEAAEEEKKTLNQLLRLAVQQKLALTQRLEEMEMDREMRHVRRPMPAQRGTSGKSSFSTRPSSRNPASSNANPF
The following text describes a protein:
Function:
Required for normal bone mineralization.
Miscellaneous:
MISCELLANEOUS: Membrane topology is controversial. The N-terminus is cytoplasmic and the C-terminus extracellular according to PubMed:24715519, while both the N-terminus and the C-terminus are extracellular according to PubMed:18442316.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDTSYPREDPRAPSSRKADAAAHTALSMGTPGPTPRDHMLWSVFSTMYLNLCCLGFLALVHSVKARDQKMAGNLEAARQYGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLSKLAKDSAAFFSTKFDEEDYN
The following text describes a protein:
Function:
Involved in the biosynthesis of homoterpenes, attractants of herbivores parasitoids and predators (e.g. predatory mites and parasitoid wasps) (By similarity). Component of the volatile terpenes biosynthesis pathways. Converts mainly nerolidol to dimethylnonatriene (DMNT) and, to a lower extent, geranyllinalool to trimethyltridecatetraene (TMTT).
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MELASTMSVAMALAAAIFVVLCSVVASARGRREKALKLPPGPRGWPVLGSLGALAGALPPHRALAALAARHGPLMHLRLGSYHTVVASSADAARLVLRTHDSALADRPDTAAGEITSYGYLGIVHTPRGAYWRMARRLCATELFSARRVESFQDVRAQEMRALARGLFGCAAGRRAVAVREHVAGATMRNILRMAVGEKWSGCYGSPEGEAFRRSLDEAFAATGAVSNVGEWVPWLGWLDVQGFKRKMKRLHDLHDHFYEKILVDHEERRRLAQASGGEFVATDLVDVLLQLSEESTKLESESEARLPRDGVKALIQDIIAGGTESSAVTIEWAMAELLRHPEAMAKATDELDRVVGSGRWVAERDLPELHYIDAVVKETLRLHPVGPLLVPHYARERTVVAGYDVPAGARVLVNAWAIARDPASWPDAPDAFQPERFLGAAAAVDVRGAHFELLPFGSGRRICPAYDLAMKLVAAGVANLVHGFAWRLPDGVAAEDVSMEEHVGLSTRRKVPLFAVAEPRLPVHLYSATE
The following text describes a protein:
Function:
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
Sequence:
MRIRLATNNPYKLAEVSHILAPFCIEVERLDAEKVEIQHDDVVVIARKAAEFLCSRYGDFVVVDDTGLYIEALGGFPGPYAEYVYRTIGLKGVLKLLEGAADRRATFKCAAAICIGGRVEVFVGEVRGYIAHEPRGRGGFGYDPIFIPEGMTATYAELGEEVKNKISHRAKAFSQLGAWLTNRNLFK
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
Subcellular Localization:
Cytoplasm.
Sequence:
MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
The following text describes a protein:
Function:
Probable DNA helicase that may play a role in DNA repair during meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MCDQYLLSYYKDEIIEILKDQDEHKHFSVNVNFVEMSGNEPNLVNDFLREPEKTLEEWNNALKRVETNLLLQFEDLYTIKNNIHCRIYSLPMYPELHRTKFPQNDDVNKFLQVTGTVVRTTQMKMLEYQRQYICTKCKHTMVVTAEYEMKNVITPPRQCTNPEGCKGTTIVNLGELDPTFCKDYQEVKMQETVNKLDIGCMPSSIWVTLEDDLVDSCKPGDNVTVCGLVKRRSSQFIIGGKIDIELVIRANHVHVNNNSSAVLSITPELKDMFQAFWHTYSGTPLAARDMILKSICPELYGLFIVKLAVAVVLAGGSSQHTKSDTGVRVRAEPHLLLVGDPGTGKSQLLRFASKIIPRSVFTTGVGSTAAGLTVTAVMENGEWQLEGGALVMSDGGICCIDEFNTMKEHDRTSIHEAMEQQTISVAKAGIVCKLSTRCSILAATNPKGNLDASQPLHMNVALASPLLSRFDLILLIKDKVDDGWDSQMIDYIFTARENSNSSKLIESINWTIETLQAYFAIIKKNHPMLNDDAHRILSGYYQAQRRKNCRNKSRTTVRLLDSLVRLSQGHARLMFHKEVEIVDAVLAVILVETAMECDSSVFNLNFDTRRDFPLDPEQNYRELAQIVLQELQLNDLLEKEFAKGVCALCPGNANCVHKNTKMFEKIIKVCEPQPSTSKINENEKINTAHNKNSDARPSSSHVNKDKIELDEKDTRKKQIGESITIANEEEIIKNKRNITKNVNKDITEEPVSNKKRNKRENPPNPKRIKLKSKENEIKDDLAALNAMPSVNDIFRMDNEIGVTIEQNKPEETEPSQVPSQRTKTRQFLHKFRFVPKEDRPPIADETTCENLEISFKDVKSSTMLEPEENVKKFKFKKASKHVEMFESLEDLDDLDLDI
The following text describes a protein:
Function:
Probable cell surface metalloreductase. May be involved in iron or copper homeostasis (By similarity).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MLEKRHGDHHNANIKYGTFVLVISLLVVCYIAVRNLTQPEVRARTKRDLRLPLWLSVLLWTALVIGMGVIHVEELNEAAKRFGRLCYALLPLIVFLAIRPSPLPRTFYLKLLPLHKWLGRLATLVGVVHGVLYTVHFVKKNEFYKVFKFDNFLGVIILAVFLVMVVTSLPFFRKRMYSLFYTIHYLSAWFVAIATIFHARPGVGWLFFWVALFMGSSLLYRVLASSTVQIESTEAMGPDLHRVTFPRSILPEFFVPASHIRVSRTLRNPLSWISSTHPYTISSLPSDDHVELIVRPTKFSLAHAASGTQFAVYGPFESLPDDFFSTANRVLVFAGGAGISFALPVVQTLAKAGISHKLVWVLRNKAGVSEVESRLGETPTDIYITGQDPFLGEGVVYAKDAEGTAGLLSEDMEMEEIGQEDEDRERDELDDLLSEDEGSSSQDSTKGAHKNKGKDQDNGKREASQSITYHDGRPQPADTASAYFLDRSAPEGKWILACGPNGLVVTAEQAAKKTGVRFCNETYSM
The following text describes a protein:
Function:
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
Subcellular Localization:
Chromosome, centromere, kinetochore.
Sequence:
MDSIELLNDTMKRLAAKEDSEITAEGWLIKAVSVGETFLKDLLCANKHNKRIALLQKNNRQNDTSHQNGDISLESDLDESKEESKDVSSCSLLNGEDRDSHLLPVEDARNILTMYTMLHSPLVQTNNQVDPESLLPLWILCDGKDPERTSLIGCELAHTGSGQESDSSPFILTTVTSDDPISSKADVPTLQQVILEAHEDLASKYIASQGFAQFEVVSQLSADTTLAETQSSDSSYIAVECTWNQVKKILESPRDASCKVLIRAVPGDMRNTPLEVYKELCLLKTFADSLETGEVNWITREKTSSIQDLITTFLDEIKGGPIYKRKTGDDADDLDAQLCWKAAFDRSDLDFTERLWNILRNNATCYEDITTAFSMVINELNRGQIQPMVHRSNQTTLAQELRMLYEDPAHMFSLNHSPMTHLVEIAIDKIQRDYTNFFLAKKLTTLYSLEWFVQSVDLLTPGELVKRLRSLHCILEVSMLASQSLGLPTNNILTLIRNALDYYRNNSPDVQHTFVLPVEQTSVVSLYQNQQPSVWRLTTQCGCRGDKTSSVYQLSSRPFIDSVIQTTDMAIDDEGEEQEPFHYFVTRVKRDLEPFVPVNSFETI
The following text describes a protein:
Function:
Phosphorylates NAD(+) to produce NADP(+) in a calmodulin calcium-dependent manner. Does not possess activity toward NADH. Has broad specificity for the phosphoryl donor, as ATP, CTP, GTP and UTP can be used interchangeably and produce similar efficiencies. May play a role in producing NADP(H) needed to regulate the elicitor-induced reactive oxygen species (ROS) burst by sustaining the activity of NADPH oxidases. Does not seem to play a role in photosynthesis-driven growth.
Subcellular Localization:
Mitochondrion outer membrane; Peripheral membrane protein.
Sequence:
MVKPLGEGTRDVSNVGCKSVDLLLASLGGLAAAVAAAYAGELLLRRRKLDQGASMGYKDVKIAPLIERKDSGRRSNLERFSHYVARQLGFEDPNEYPQLCKLANGYLLKTKGYDENVDEYLENEAERDSLYVHLLEEFDRCILTYFSFNWTQSSNLISQALSDESDQKVPKLKDFVMAATRKQRFERVTKDLKVKRVISTLVEEMRVIGSGSSEPHCTEVMSPVAHNKRSPVLLLMGGGMGAGKSTVLKDIFLESFWSEAQADAVVIEADAFKETDVIYRALSSRGHHDDMLQTAELVHQSSTDAASSLLVTALNDGRDVIMDGTLSWEPFVEQMIEMARNVHKQKYRMGEGYKVSEEGTITEKYWEEEEEETKENGKQQNLKPYRIELVGVVCDAYLAVARGIRRALMVKRAVRVKPQLNSHKRFANAFPKYCELVDNARLYCTNAVGGPPRLIAWKDGNSKLLVDPEDIDCLKRVSSLNPDAESIYELYPDPSQLSKPGSVWNDVVLVPSRPKVQKELSDAIRRIEKAQPKN
The following text describes a protein:
Function:
First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
Subcellular Localization:
Nucleus.
Sequence:
MDLRNVLNDSSSGPVAPRAAVSTPDRPPPHQQHQQHQQQQPPHPQYSQHPPPPPPQHPQPLLQRQQSYHLQQQQHQHQQQQQQQQHHPAYPQPPTTPGQAPPHPQQQHQQSYIDYNHQTRPSPVRHISQDPSYGTQRMPPAAFASTSPFTGPPAPGPSPYANRAPPPPPLQQVSAHDPRSPSLASGPGPSPYRHTPTSSISAQSGGYPFPPSAQHTPTSPVQRPYNQYPPSSTGAAYPSREGYPPTPGGSVGVAGPQQQQQQQQQQPPPPPPPPGPGPGPGPGPGPGSAGRAPYLQGPPVRVPQTPPISTAHNPHFQRSHSTHSSSTPTPTSAHSQGPPGHSHSHSHSHPQVVYGAPFGRASPVTGPQTGGGPQGGQFLVDPQQRQSSQPGTPVAGPGGGGPGPLTASTGPGTIPGTARPLPPQATVVSSQAQAQAQAQAQNFNHYSQPPSPYRQQRLPPSGSSAAATTHHQHLNLNSPRSSAQQQQQQHHHLQHQQIISSPHSHHPAPPQPPPPPPPPPPPPPQQQSLPRQPSAQSIYDAREREREVIRERSISISPKTRVPSLPSSAGRPATATSVVSIPESEPPRLNNHTAATPMARYRDEVRDGDLGHNAAATAAVKRKLDDRELRPDELERRDVRPPPFDNNRARPSHTPNKSVKRRAYDGPPPWAQQATRGTTLKEPNFVLYKPVHAPGQGPVQLNGHSRHASPEEKRPVPRAHEPTPRAHEIRHSERSATPGTQGPPPEAQAKWGPLGPWEPTLTGDVPQDTMAKVMADFFFHYIVLNENMGEIQSRGIQFEIEAKFGELIDRNTNQRIDLGVLSPAILKEDDYVYPFRSIMTEAQHRSYNEFLNHQVVVSKNPKSNIGRERPRVPISYEHKYEIDRFYAIPPQIRDKHLPVTVANLLASKGRDAKVRVSYKENKDGSREQIAKIVKARLKDLSIHFPEHRLDCRISINLEMPWEGPLEELEAYATSANKGQSPDRRKNRLSYGHCSYQFDLTQVVENVSGRDEKKHELEIELDPKAVLDQGRRAREGQPNQYFDLVEGFLNNIRIMAKMCA
The following text describes a protein:
Function:
Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II. Essential for vegetative cell growth and chromosome segregation.
Subcellular Localization:
Nucleus.
Sequence:
MGVPAMFRWLSQKYPKIVSTVQEEQPKKVGDEVIPVDRTGPNPNGEEFDNLYLDMNGIVHPCSHPEDKPAPKTEADMMMAIFEYTDRVVGMVRPRKLLYMAVDGVAPRAKMNQQRSRRFRAAREAKEKDEERAEFLKMLNSQKASRGEDINSLEEVVEKTWDSNAITPGTPFMHLLAESLQYWCAYKFTTDPSWKDMKVIISDASVPGEGEHKIMNFVRSQRAIPTHDPNTRHVIYGLDADLIMLSLATHEPHFRVLREDVFFDSGKDKACTRCGRKGHIRNNCEFPDDGKKLTEEEAAEEWAASEHPPKPYIWLHTNILREYLAVEMETPKRRFKYDLERSLDDWVFMCFFVGNDFLPHLPSLEIRDQGIDLLISIWRDLAAEMDDYVTKDGFPDMRRVQQILGALASREADIFKKRKEVSDRQAANRARREAQQNGRGRGRGDDTYSSGPPQKRVKESTDTYLNSGTIFFDPKDAQSNDTRRDHAAMRSPMPEAEGTQETDSATGVEAPVELGKRKADELEDADNGTPGRNTPVVPASPAAETPKKEDGTPEDTIKLWEDGYEERYYEQKFHVAPDDIAFRNKVARQYAEGLCWVLAYYMQGCPSWTWYFPHHYAPFAADFVGLEDMDPRKLFEKGTPFHPYEQLMVLPFIDSKRLLDAMATKYPELSDDERKRNEFGKETLMFSQEGGLFDDVEKALYRKGVKKHSIDPAQSRALHGDIEPHDLFVLDSQLVPPFDVDGDSEFEIVQDGSMRVYYEMPRLNSKNAHKSVLLPGTKMPTPALSPGEAESVRRSNERGGWRGGRGGGRGGGGRGGFNDRRNNDNMRGDYQNGGRGGYNNGGRGGYNNGGGRGGYNGNQGGYGAPQNFPPPFPNSWPPPPGGANFVPPPPPGWVPPPQQGGYQGGGGYGGPPGMPPAQRPAWMGNAPPHHGGPPPQQAGNNSSLRNEQYYRPADEILGRNGGGSGGYGGHRNDNPYNDRQPRNDRGGARGGRGGGRGGGGGGGGGYGGGGNRQSHNSNDYR
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MGLLLLQTQPGAKATEDLRLADGPLKTGCGKESFRGLCKGCLSRVSAREAPERDKQTGDERPSTPSPSPQLAAEKNSYLYSTEITLWTVVAAIQALEKKVDSCLARLLTLEGRTGTAEKKLADCEKTALEFGNQLEGKWAVLGTLLQEYGLLQRRLENMENLLRNRNFWILRLPPGSKGEAPKVPVTFDDVAVYFSESEWGRLDKWQKELYKHVMRGNYEMLVSLDYAISKPDILTRMERGEEPCPDGPWGPEEGKEREAARPKRPGAGLPPHPEHIPSPVSPAQEEPTETQVPDHQQDSETRVIPPETSTGPPACTSILSSVKQEEESSDGESSASPPRDILPSMGPGGGVVIKTEAQSEDEMMPEQLFLGKSPSQTQCRLPKGPRSGTGGPGGLHAGGVPRVRAGAPRPPGGLGEPPRILPRRRERTFPCPDCGQSFRLKINLTIHQRTHVEEEHREARGSSPPAWGEAHSTLEPGEVVVPGPVIRWLPEEPEGHRSLSGRSFVGRRPAATKVYHCSECLRFFPQRKSLLLHQRLHTGNGQGWPACPYCGKAFRRPSDLFRHQRIHTGERPYQCPQCGRAFNRNHHLAVHMQTHARGQAGPHFAAPPGRPGSPPLRRPSRIEEG
The following text describes a protein:
Function:
Low-potential electron donor to a number of redox enzymes.
Sequence:
MGKVLVIYDTRTGNTKKMAELVAEGARSLEGTEVRLKHVDEATKEDVLWADGLAVGSPTNMGLVSWKMKRFFDDVLGDLWGEIDGKIACAFSSSGGWGGGNEVACMSILTMLMNFGFLVFGVTDYVGKKFTLHYGAVVAGEPRSEEEKEACRRLGRRLAEWVAIFVDGRKELLEKIRKDPARFVD
The following text describes a protein:
Function:
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Sequence:
MITAALVGVVLYSCLLISTHSEIQILPTTSGWQPGDQHANYYKKSRQDGLLHTTDKKINIPLRKGTYTPSRKRLEVRSKAAVSCDVPQCSTMGTDILRRGGSAVDASITVALCIGSVNGFSSGIGGGGFMVVKDAKTRDLSFDFRETAPLAASKDMFKDDPKKAQFGGLAVAIPGEVHGLYEAYKRYTSGVLSWKELFEPVIELNERGWTVDKAFELALEVTEDDLSAYGNGDWSWLYVDTPSTNASPFKARPLKSGDVLARKALAETLTLIANNGSSAIFYDPKGPIAPKLVDAINRAGGVASLEDFEQYQTIVEEPVRGEFYGREVLVANNPSSGPALVVGLNIIDELDKKEREKDTNAPGRCVGILKKTANWFRQGFSLLGLATNGLIPRDSNPISIQRLTEAMKYTSSARTELGDPADVSNKKRVEYLLTQDWTDKAVNNISDYHTRPWEDYQPAYEVSDSAGTAHFSVLDENGMAVSMTTTVNLLFGSLVYDHVTGVILNSEMDDFSIPSRDNAYELRPSIYNYIAPGKRPLSSTTPTIVYNKKTDHVELVLGAAGGSRIVTCVLQAIVRKYSYGLSLLQTVAFPRLHHQLIPEIAYVEIGGRKSIGQALKARGHGVEYWIPRSVMNAVSREDNGEIHAVADYWRKGGGSDGY
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere. Nucleus. Chromosome, centromere, kinetochore.
Sequence:
MEGGGGGGGGAIELRRRMAAQCLAFERQIADGRERTKAAASAFSAALLSARSLSNHTISQREKSNQLKDQLRKLEADFAQALSIQGSNKTKYDLTGQSITNAIATNDQLSCLVTDKRASRDEYANVISSQLEAIEALEAKTDAAGKKNLDEAFMWYKKFLGFQVVGGEGVKFVFSKIDIQNPDNEYSFCIKLNKDRYNLLQCTPFLKDSEELVKDLNCSNDLFKFVRIMRERFQAAAINGFLPASSLCPDMSSSITDSSPPALSIDTGRESTTTTSQSHSRSRAKNQDNPTKRGARPSNLLSSTRRSPRVAVSALYHPLRHNFSWLLIFTWCLFCSQAADATNRY
The following text describes a protein:
Function:
Efflux pump that provides the dual role of gliotoxin export and self-protection by allowing the fungus to evade the harmful effect of its own gliotoxin production. Moreover, it also contributes to the virulence through gliotoxin secretion.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSRPSIEESKQELSSSPNDSVMGKDPAPEEEMQYPSGFALSVIMAGLLAAIFLISLDTTIVSTAIPRITDEFHTVADIGWYGSAFFLTLASFQGTWGKIYRYFPLKLSFLAAVLLFEVGSLICAVAKNSVTLIVGRAIAGIGAAGISSGSYTILAFSVHPRRRAAMTGAIGASFAVAAVAGPLIGGAFTSHTTWRWCFWINLPIGGVSAGLIAIFFKAPPQARAKDVPYKEILLQMDPSGIVLLLGAILCFLLALQWGGSAKAWGNADVVGTLVGFGLLLIAFAINELWLQEKAMIPPRLFKGQTILFSSLFTFFFSGSFYLLLYYLPTYFQSVKGASASDSGVRTLPLVLGDGLFATLSGAVLGIIGYYMPLLTLGGVLTTVASGLLYTLDLDSGANAWIGYQAMAGIGIGLAIQVPMMASQAVVRVEDLSTVSAIVLFFQCMGGAIFVQAGQAAFTNKLVQEVQRHLPNISAARVTSTGATELQSEFHGHELQVILEAYVAGLKDAFIVAIVLAGIATLLSFGSGWRSVKSKKEEPKAQP
The following text describes a protein:
Function:
Can degrade casein. Could play a role in tissues homeostasis and repair.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Domain:
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
Sequence:
MVARVGLLLRALQLLLWGHLDAQPAERGGQELRKEAEAFLEKYGYLNEQVPKAPTSTRFSDAIRAFQWVSQLPVSGVLDRATLRQMTRPRCGVTDTNSYAAWAERISDLFARHRTKMRRKKRFAKQGNKWYKQHLSYRLVNWPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLGNAFDGPGGALAHAFLPRRGEAHFDQDERWSLSRRRGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKRLGRDALLSWDDVLAVQSLYGKPLGGSVAVQLPGKLFTDFETWDSYSPQGRRPETQGPKYCHSSFDAITVDRQQQLYIFKGSHFWEVAADGNVSEPRPLQERWVGLPPNIEAAAVSLNDGDFYFFKGGRCWRFRGPKPVWGLPQLCRAGGLPRHPDAALFFPPLRRLILFKGARYYVLARGGLQVEPYYPRSLQDWGGIPEEVSGALPRPDGSIIFFRDDRYWRLDQAKLQATTSGRWATELPWMGCWHANSGSALF
The following text describes a protein:
Function:
Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.
Sequence:
MTDRHIFPDHKTLVFRSLRGLVASHPYLSLIPSQKVVYRADHDPSKVSLICGGGSGHEPGTVGFVGAGLLTASVAGDVFASPSARQVMEAIKRVHSDKGTILIITNYTGDNLHFGLAKLMAQSAGLKNVELVVVGDDVSVPKSRGKYVGRRCLAGITLVCKILGAASEVDVEFQNLVTLGRSLSANTASVAMALDHCHVPGRSGEADWHLPEGKIEIGLGFHNETGVFSIPQPPPDVLINKLLDLLLKQDDPERSFVKFKDGDELVLLVNNMGGMSVLEMGSVVDEVLIQLESRGIVPTRILNGPFMGSMNMPGISLSLLNLTNVAEECPFVDTSKLAEFLDAPHNSVAWPATSQVYPLPEKLANRKREDKFVDVEEEKKEEVTGGPQLFGNEELIRKAMKQAAEDVLASEPKLTKWDTIVGDGDCGETCALGAQATLKALEQGLGSDGELVHFFRVLTEVIDGSMGGTLGAIFSIFLAGLTTALIDAASSPNGAPELTPAFFGQVTSSALETLKARTAARVGHRTVMDALIPFGETLAESGDLKKAVEACRKGGDSTVDLQAKLGRATYVGQLEGDMPPDPGAMAFVTVVEGILKAYSS