lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses.
Subcellular Localization:
Plastid, chloroplast.
Domain:
IQ domain mediates interaction with calmodulin.
Sequence:
MASHHHHNHNHVCSRHQNHHNNTPQFATSPNCCNKSNHPSPPPAEDNLLHLVATYLQNHQQETQCSCETSCQNFNVIRSQNRVLRQHKNVPREYDQVVLSCLLRKIDDLESSLNKFSSFYDKRRDRHSTLRDSAARVIQTHFRSYLVHRSISFRQLKELAMIKASFLSLKSSVSGKLIFPFKVVSRKATDLLLQLDSIQGRIDPMIRSSKRSLSRDLVRFVQYVDDCVVKRYGFVVKSGSGIKLNGKKPQGFGTSSEDEDNNADMSDDSEEVPVSSIDKRKVASSKSRTGVVIEGDVVKPPVMKFVVLDKNRNVCQVYGNRHDLTSSAEDDSVDGDEETLVMSRDNGRKQSLKARNGVSVKGGGGKTTRVVKTVSFDENGNVCKVYGDTHDLTSSAEDDDSVDVGEETLVMCRDEGKRRSSKTGSRVLVKGSGGKTNRVVKTVSFDENGNVYKAYGDTPESSIISEEDDSTSGSNEGNGEEKGNVNEVEEIKYVPKENESFEEEEEKETDSENEVSSSEGSEGDKRVTKKEVQHQKGSLMFSPPLPLKMEP
The following text describes a protein:
Function:
Controls axon guidance across the CNS midline by preventing the delivery of Robo to the growth cone.
Subcellular Localization:
Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.
Domain:
The cytoplasmic domain is required for function in axon guidance.
Sequence:
MISTTDYPTVETTTTAEELYAEYISAPASSMSPAAIAEHLQQNQITFEIPSAHDLRHIDALNSFNALLQRIGNAAVSYDPAPPSGWSPDGSISTEQLSKSVVLDLADLRDRSEESGESSWWSQIFGDADMHVIINYLWIGVVSSLVILSLVFILFSCYFYRKFRTWKKCNKDIRAQIHAASDSYSSHLVGCDASRLLLHQQMQHPHHRSSEAGFYQIESPPCYTIATGLPSYDEALHHQPRHFAYGMKFVYPSLAAVHHHHHCISNWEKQEPLNKLQKCKLSAAAAVEEDKADSSSSTSASASPSSSESSNLATATPAICINMPSGRQDEEVDNSDSDSAIAVAVAVAQSLQPAAPADDDCASLVVVVAA
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Sequence:
MASGLQVFGQPASTDVARVLTCLFEKNLEFDLVRIDTFKRQHKLPEFIRLRDPSGQVTFKHGDKTLVDPRAICRYLCTQFPNQGNRNLYGTGSLERASIEQWLQAEAQSFNPPSSALVFQLAFAPLLEIPQDHMVIAENERKLQQVLNVYDEILSKNEYLAGDEFTLADLSHLPDSQYLVSSERGMKLFTSRKNVARWFDQISSRKAWEQVVKMQMEHPGAFE
The following text describes a protein:
Function:
Glycosyltransferase involved in the arabinosylation of xylan, the major hemicellulose (non-cellulosic component) of primary and secondary walls of angiosperms. Possesses alpha-1,3-arabinosyltransferase activity, transferring an arabinofuranose residue to the xylan backbone.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MKAGERPKLVRGVRQESRRFRLLVIVVGFFLVSLTFVFVSKPDAILFSLNGKLPVEQAPTSILIQQKVNEPSGESRKTSTDALRGDPKVVDDEADAKPKGTGGGSEEEEGRVLSEPDPTSGMMEPTHNKDGNGHKSHQETLGGGGDGESKGNDEEGEHAEQKHKVTLPTVSNYTIHDAAEDTENAKQEGMNNVQQGSKPLCDFSNFRANVCEMRGDVRIHPTATSVLFMEPEGSQRDEVWKIKPYPRKGDEFCLSHITEVTVKSSKVAPECTKYHDVPAVIFSLTGYTGNLFHDFTDVLVPLFTTASEFNGEVQFLITDMALWWTIKYQTVLQKLSKYPVIDFSKDDQVHCFKHAIVGLHAYMEFTIDSTKAPHNYSMADFNRFMRGAYSLGRDSVTVLGEYPKIKPRLLIIKRHRTRMFLNLDEIISMAEELGFEVVIDEANVSSDISRFARLVNSVDVMMGVHGAGLTNCVFLPQHATLIQIVPWGGLDWISRTDFGNPAELMGLRYKQYSIGVDESSLTDQYPRDHEIFKNPISFHQRGFDFIRQTFMDKQNVKLDCKRFRPILLEALDNLNP
The following text describes a protein:
Function:
Mitophagy receptor which plays a role in paternal mitochondria degradation in embryos after the two-cell stage.
Subcellular Localization:
Mitochondrion outer membrane; Multi-pass membrane protein.
Sequence:
MVDLSKNDGGSGKAGKGVSDAIDTVLYYVVDLKKQQPMVQLGVGAGFGTVTGYFVTKGGRLVAATVGISFLLAQFAIHKGYITLNESKIERDMKNLHKSVMNKVSGKKVINISDSFVSEYRWILGGFAAGMLIGFSVA
The following text describes a protein:
Function:
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
Subcellular Localization:
Nucleus. Chromosome. Note=Loaded onto the nucleosomes of condensing spermatids.
Sequence:
MSTSRKLKSQGMRRGKNRTPHKGVKRSGSKRKYRKSSLKSRKRCDDANRNLRSHL
The following text describes a protein:
Function:
Isomerase that catalyzes the conversion of deoxy-ribose 1-phosphate (dRib-1-P) and ribose 1-phosphate (Rib-1-P) to deoxy-ribose 5-phosphate (dRib-5-P) and ribose 5-phosphate (Rib-5-P), respectively.
Subcellular Localization:
Cytoplasm.
Sequence:
MKRAILIVLDGVGIGELPDAFKYNDEGSNTLVNTAKVVGGLNLPNMGKMGLSNIEEIPGIPKEEDPIALYGKMAEASPGKDSTTGHWEIAGLILEKPFPVYPNGFPKEIIEAFEKAIGRKVIGNKPASGTEIIKELGEYHMKTGYPIVYTSADSVFQIAAHEDVIPVEELYRMCEIARAMLQGDHAVARVIARPFAGSPGNFYRTPRRRDFSLPPFKPTLLDYLKQNDYDVIGVGKIEDLFAGKGLTSSFHQENNTEGINNIFKAWEKLREGLIFVNLVDFDMLYGHRNDPQGMTRALKEFDDALPDVMGLLSDFDLLIITADHGNDPTTPSTDHSREYVPLLVYSPNFKRTFSLGIRKTFSDLGKTLAEFFEVENDLCGESFLNEIEKGWKGS
The following text describes a protein:
Function:
Putative NADP-dependent oxidoreductase.
Miscellaneous:
MISCELLANEOUS: Despite its name, it shares more sequence similarity with the sugar epimerase family than with the short-chain dehydrogenases/reductases (SDR) family.
Sequence:
MRVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAGENILNPLRRWNETFQKEVIGSRLETTQLLAKAITKAPQPPKAWVLVTGVAYYQPSLTAEYDEDSPGGDFDFFSNLVTKWEAAARLPGDSTRQVVVRSGVVLGRGGGAMGHMLLPFRLGLGGPIGSGHQFFPWIHIGDLAGILTHALEANHVHGVLNGVAPSSATNAEFAQTLGAALGRRAFIPLPSAVVQAVFGRQRAIMLLEGQKVIPQRTLATGYQYSFPELGAALKEIVA
The following text describes a protein:
Function:
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.
Subcellular Localization:
Cytoplasm. Preautophagosomal structure.
Sequence:
MADTQVLKFQPWNSAPDVSFWQTLTSLKLDKFQLDDQAQRITGYFTPGRSENVPARFTIDESAFPNAEGTQRDGRDTDRARYEWQAPGLLYNTNTLEAFKKLDKAKLLRDAGEKILDLVLEGGNEDVSIDHLNSFVLITFADLKKHSFLYWFGFPALSPPAPFQYGAPPASVSSVLTLKEQVEVLRGLLKLRRVNRDTGVMEGNFASFFVVERLAGGTTSEQVVRVLDVQKWRAAAHNADDVLETIFGFVDPCPLKTNPGWPLRNFLALLTALPAGKVDCSQPLKVISFREHVHQFAEVPDDFEWKSSVVFEVKSDQSFMVNDRSRQDVRVMGWEANVRGKMGPRMMELGGILDPIRLAETSVDLNLKLMRWRQLPSLDLELLAQTKCLLLGAGTLGCYTARSLLAWGFRNITFVDNSTVSHSNPVRQPLFEFKDVGKPKGECAANALKRIFPLVNSQAVNLTIPMAGHALSSSQLMEEATKGLETLEQLIESHDVIFLGTDSRESRWLPTVIASSKRKILLNAALGFDSYLVMRHGVYPEHENGDSSQPSLGCYFCNDIVSPRDSLKDRTLDQMCTVTRPGLAPIAAATAVELLVAVLHSPQGKYAGAEKPTDGSAPMDYIPHQLRGFLNAFQNMVITGEAFDKCIACSSKVLGAYADDALGLLEKACNSSAYLEELTGLNQLTEEADSLMVDLEDSDEDGDMI
The following text describes a protein:
Function:
Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.
Subcellular Localization:
Cytoplasm, myofibril.
Sequence:
MSTPGPSKWHPTTGYYDYNYGVGINFYQPMVDYIDQKERGGRTSYPHLPWTDELGLSQYDPKTIKSYSNEALDRVARQTEASAKEKLRDFRATTKSSFMLSKCVSAASITEKVNVKNRKKKEIVRQIKTLKSKMADDLGYDHRKEDRDVELVLKGSQKYLRGRSAKGIEAFLQSESYKNIAQGVEFDLANTRNIENRRFVDTQQFTKHLKVMDKRLLNQLEEKCVEPLDALSRELKGFDKRTAEYFFDTSKATSIEIEQLNARVVEAETRLKTEVQRIKKKLQIQITELEMSLDAANKTNIDLQKTIKKQSLQLTELTAHYDEVQRQLQVTLDQLSVSQRKVQALTAEAEEIRGNYESALRGKRAAEQACEEAGTRINELTTINVNLASAKSKIEQELSTIVADYDEITKELRISDERYQRVQTELKHTVEILHEEQERVVKIEAIKKSLEIEVKNLSVRLEEVEANAIVGGKRIISKLEARIRDIEAELDEEKRRHAETIKILRKKERTVKEVMIQCEEDQKNIALLTESLEKANGKVALFKRQLQEQEGVSQQSVTRVRRFQRELEAAEDRADTAESSLSLIRAKHRTFVTTSSVPGSQVYLVQETRSSEQI
The following text describes a protein:
Function:
Transcription factor involved in regulation of RNA polymerase II-dependent transcription. Also involved in regulation of mitochondrial DNA recombination, maintenance and repair, and generation of homoplasmic cells (By similarity).
Subcellular Localization:
Nucleus. Mitochondrion.
Sequence:
MAQYTKAMGTVRKYTPATLKRDGKPAFVYVYRHLQTGQVAYTQVPGVTEHHLNRQFKDPNWENKRPTMRQDLWRPMAVADFGDHQAACDAYDGLVYLRYKRTHDGKKDIKGWRKTNAAGNVWQDGQYRPVYTQEALADLSTVTEAVKVPVTIHWEDLWRRGAAESWPENADHSVLKRWDAIYPQSLEKRLAKEAKVPGETTAEQ
The following text describes a protein:
Function:
May contribute to coordination of muscle contraction as regulatory subunit of a nonessential potassium channel complex.
Miscellaneous:
MISCELLANEOUS: Gain of function uncoordinated rubber band response is phenocopied by exposure to the unc-49 agonist muscimol.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Note=In body-wall muscle cells, localizes to dense body-like structure which connect the myofibril lattice to the cell membrane. Colocalizes with sup-18.
Sequence:
MRYAVFIFLIVLIDLIYCWNSKRSFFIPDFLGSGDGTPKSKTESVIEERMEYGRMILLVCNKTCAKHRSDIPLWLKEFNQKKGYQEPETITYYYHTYRQAVSFIDTNETDVFPNLIYFIGVKRVVFNGDVNIREDVNDWIASLDQLILLEPRVYEDLNVILSDTSNCSSKYLLLADRPKCPQPSWSIVARIAQDHGIQPVKIGHPLDGLTHVLLYKRMPYLSEASCHLSVLLYENSYSDFGDDINPLVVSDWITTLLPLEEGSCPALFETYWHPIVDELTELQQIFYSAELEISERNKRPAFVLVGLTGGIAVIILAFSIFWGLNGSGFNKD
The following text describes a protein:
Function:
The monopolin-like pcs1/mde4 complex is essential for accurate chromosome segregation during mitosis and meiosis II. May clamp together microtubule binding sites on the same kinetochore, preventing merotelic attachment of microtubules. In contrast to its S.cerevisiae ortholog CSM1, is not required ofr mono-orientation during meiosis I.
Subcellular Localization:
Nucleus, nucleolus. Chromosome, centromere. Note=Nucleolar during G2. Localizes to the centromeres throughout most stages of vegetative growth and meiotic development apart from the horse tail stage of prophase I. Localizes to the central core of the centromere.
Sequence:
MRKNNMQTSKDSELKEQAKGKSSKLIHKLPKQRTRISQGQMHSTQDFVNNEDQDAYSVRENENELHINNSGMSELNKKLQLPNVELSTLSHTQEQEFNELNKLIRKINELQEFYLLEDLAKPVTNAGADADDTIVKDLKKELENEKKANHSLKNELLKTREQIKNYSKINILIKELFGLEVADCIEDEDGYRFNCKNTGRRGTLEYQLLLDDQNFTFTPRLNVQTDEELMKHLPDYLLEEIIFTKEQGKLFSARLMKALQD
The following text describes a protein:
Function:
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
Sequence:
MSDIPFTLDQLRILKAIASEGSFKRAADTLYVSQPAVSLQVQNLEKQLSVPLFDRGGRKAQLTEAGHLLLNYGEKIITLCQETCRAIEDLQNLQGGTLIVGASQTTGTYLLPRMIGMFRQQYPDVTVQLQVHSTRRTAWGVANGQVDLAIIGGEVPAELQETLTVLPYAEDELALILPVLHPLAQAETIQKEDLYKLKFISLDSQSTIRKVIDKVLSQGEIDTKRLKIEMELNSIEAIKNAVQSGLGAAFVSTTAIEKELEMNVLHIAPIKNVEIRRVLSVIINPNRYRSKASAAFIREVLPQFSTHPDALDPERLFANPYSSNNGDRQGDGKDGKGSIEIDSVT
The following text describes a protein:
Function:
Catalytic ribonuclease component of mitochondrial ribonuclease P, a complex composed of rswl/MRPP1, scu/MRPP2 and mldr/MRPP3, which cleaves tRNA molecules in their 5'-ends. Essential for the structural and functional integrity of mitochondria. Function is essential for pupal development.
Subcellular Localization:
Mitochondrion.
Sequence:
MYNLRLLRNLLPIAGHAHPRWLASQHKRRPQPGSLPADRLDQLRSDLFERRHELSGAEWTEVRRSLVDGYKHINGHNVDAVILGVCSAPNQLSLAKSYVEFLRSRGSKPNAATLGRLLRVYNAAYHERPLSEAEQSEILQICRSLQAEHETLDASSCENVIHGLVATSGDDWQRGLPLLEMMKVTSTPSVAAYSALAEKAFSVATPEQELAWRLLEEMATARKPPKCEVYLALLNRLANETAQLPAQLSLLLQFLERHEILVSQRVAIRLQELSSQVPQLLHTRTTHLGGLGKCQSCQQHLQPVAISDEEFRQLSECFLERVLIRRDVFQRSTPEEVARFKKFVEKTAPYDCVIDGLNVAYSTGTKKTPQQLAKLVATVVRHFREQDKRVLVLGREHMRNWSKQAMHYVHCNASLFLTSNLSHDDPFLLYATLRSGQETDFFSRDLMRSHAFHLGTELKPIFRRWQQEHQFSLVTQTQTGQIIVKEPVRHRLCAHQVADTWHVPYCAQYTPHPTDSFEVPANWLCIQMKEQTIPATKTKTKTTR
The following text describes a protein:
Function:
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNFVFLWAALGGAIGSSLRYFVGKMMPSKFLMFESFPLGTFSVNIIGCFVIGFMGHLAVKKVFGDDFGIFFVTGVLGGFTTFSSYGLDTLKLLQKSQYIEAVSYALGTNILGLTGVAIGWFLAKNFVGIH
The following text describes a protein:
Function:
Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGITYNGGKSLMNLILTVLPPTLELCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGLSIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGFPVIDMWFMEVPYRTKIVQNILQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFPLLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILIDTFTKIFTFILDPFKKKGWYAK
The following text describes a protein:
Function:
Involved in the co-transcriptional or post-transcriptional endoribonucleolytic cleavage that generates sequence-homogeneous 3' ends during late transcription. Involved in postreplicative transcription elongation on intermediate and late genes. Also involved in DNA replication and in multiple steps of virion morphogenesis. Required both for inclusion of virosoplasm into crescents as well as for maturation of immature virions (IV) into mature virions (MV).
Subcellular Localization:
Virion. Host cytoplasm. Note=Early during viral infection, diffusely localizes within the cytoplasm. Following DNA replication, localizes specifically to virus factories.
Sequence:
MAWSITNKADTSSFTKMAEIRAHLKNSAENKDKNEDIFPEDVIIPSTKPKTKRATTPRKPAATKRSTKKEEVEEEVVIEEYHQTTEKNSPSPGVSDIVESVAAVELDDSDGDDEPMVQVEAGKVNHSARSDLSDLKVATDNIVKDLKKIITRISAVSTVLEDVQAAGISRQFTSMTKAITTLSDLVTEGKSKVVRKKVKTCKK
The following text describes a protein:
Function:
Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner. Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes. Participates in ophthalmate biosynthesis in hepatocytes.
Sequence:
MEPVVPLPLDPSTMDSLAVSAKDQAILNGLAYLTDPQNDSSDLVSFKPFVLLPSPVPRFLFDQARAVQKDFNLLVHRVSHDRAFLTRCLSSVIKVDNFTAGLFHIYEQVQKEGVAQPICLGVHRSDYLLDTTNNAVMETHGVTANRQFQLKQTEINTIAAAGAGFAEKMASVHSPFFILLFTCRHVLNLLGVTNAYKHIPENRALDSQVEGFVAAWERYGSQRAIIVFVVEEERCRNVFSQRLMEFSVMEKYPSITVRRYSLRQIAEDAELKSDKTLFMHGSEVAVVYFRAGYSPDHYPTEKEWNARLMIERSRAIKCPCISYHLAGTKKVQQELAQPGVLERFLEDPKSVGRVRATFAGQHTLEMGLEGDRTVQMAMRSPEDYVMKPQREGGGNNIYGEDIKTILDELKNSEERTAYIIMDLICPAVVQNYFMRPGHRPKLLGSSCELGVFGVFMAEGDQVFHNKQGGHYLRTNDTTTDGGIDVGHAVVDSPYLV
The following text describes a protein:
Function:
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome; This protein binds specifically to 23S rRNA.
Subcellular Localization:
Plastid.
Sequence:
MTSFKLVKYIPRIKKKKSGLRKLARKVPTDRLPKFERVFKAQKLIPMSVFKAQRVLDEIRWRYYEQTVMIMNLMPYRASYPILKLVYSAVANATHYRDFDKANLFITEAEVSRSTIMKNFFRPQARGRSFPIKKHVSYNNCTKYSKEI
The following text describes a protein:
Function:
Ubiquitin-like modifier involved in autophagosomes formation. May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.
Subcellular Localization:
Cytoplasm, cytoskeleton. Membrane; Single-pass membrane protein.
Sequence:
MSSTVGLCVVALLLICITHWIFKRSRSPKIDGILPPGSMGLPLIGETLQLIIPSYSLDVSPFIKKRLQRYGPVFRTSVAGRPVVVSADPEFNHFILQQEGKLVESWYLDLFAKVFKQGENRPDGAYIHKYMRNLALGHFGAESLRTKLLSQLEELVTDTLRTWSSQESIEVKRAAAAMALHFGAKQMFSYDPEESAVDLPEKYINFSKGLLSFPVNIPGTAYHKCLEDHEKALSVMLDVLNKRRASPEETHHGDVLDQLIEDMKVENFLTDDFVVQLMFGLLFVSFDSLSSALTLAFKLLAENPTVLEDLTAEHEAILKRKANPDSPITWEEYKSMTYTLYVINETLRLGSVAPGLMRRAKKDLHVNGYTIPAGWTILAVTSALQLNPETFEDPLAFNPWRWKDLKANVVSKHFMPFGGGMKQCAGAEYSRVLLCLFFHVLVTKYRWKKIDGGDIVRTPILKFRKALKIKISENLLMLLVFSVVWVGLVRNPRLVRRQAESAQIMEKYPDRIPVIVEKAEGSEILDIDKKKLGLLNPKTHLLEFQLQYF
The following text describes a protein:
Function:
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Domain:
The F-box is necessary for the interaction with ASK proteins.
Sequence:
MALNFSHRPFSSHLSEEPMMIANGNWCSSFDNGRKNTGGDASSVDILDVLPSDPFGMDINNTFTAITGWLEDLEDDYNNQYGRRRRDDIWIGDGNRQQLFAGLSFFWNNAMQFQSSGYSYGSESLFGGAFDGSLFSTCKFPESSGENNGFGGALDGDGSCHGAFISASSVDEVLSHENARNGEVVGSSDRCNNGEEDAYVHPAIGFCLYHLRGKDLLSVSMVCKSLHTTVCDDTLLWKHIHICRPLNEKITEEALLHLTERAQGTMQCLRIVDCCRITDDCLKRVVARNRQVVKIGVPGCTRITIDGILSVLRDLKSAGKLQVKHLQLRGLFGVTKDHYDELIDLLNIDNKVKQTIQKPRFYHRGEACVSCDDDRALDIEMCPKCQNFKLVYDCPAEDCKGKKKGSEECRACSLCIQRCYHCGRCIIDTEYEEMFCLELLCAVCSKPTPKLTL
The following text describes a protein:
Function:
Xanthone prenyltransferase involved in the conversion of monodictyphenone to the prenyl xanthones such as emericellin, shamixanthone and epishamixanthone. Monodictyphenone is first converted to variecoxanthone A via a paeciloxanthone intermediate by the consecutive actions of the FAD-dependent monooxygenase mdpD and the xanthone prenyltransferase xptB. XptB catalyzes regular O-prenylation at the hydroxy group of C-7 of the xanthone ring. Variecoxanthone A is further prenylated to emericellin by xptA before being reduced to shamixanthone and epishamixanthone by the dehydrogenase xptC.
Sequence:
MLKHSSAATKENDSPKLKVLDIVSKLEPSLDHSHTHWWKLTSPQLALMLEAADYSIEKQFETLLFHYHWVVPYLGPKPDADGNFKWRSLVSDVGIPLEYSWKWDTATSGPDVRLTIEPINELSGTRVDPLNQAPSLELLHRLAEILPRLDVSWASHFLSTFYDHDKLKYIKESESETGMPLRSTMLVCFEFGRNGITTKTYMSPRKLGQQGFAPLSDYHSAIAALGPSCALDAVTEFLNNSPEGPHLSPFMLAVDNIIPCSSRLKLYFATPRTSYNSIREVLTLGGRLSTVTLESKLRAIHELVKAIMPFPPDLPDDADIPFPEQVLSPTVQDLAESSDMANQRPAFVAGYQYYFDIAPGASLPDIKFYIPIRKAQMNDQAVATGLTNWMRAQGRGAFCNAYTRVLEGLAGGRDLSKCHGLHTHICVMLKGNGEFDVTSYLAPGCK
The following text describes a protein:
Function:
Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting RIGI for autophagic degradation. Interacts specifically with ISG15-associated RIGI to promote interaction between RIGI and the autophagic cargo receptor p62/SQSTM1 to mediate RIGI degradation via selective autophagy. Also plays a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Cytoplasm.
Sequence:
MGGTLAWTLLLPLLLRESDSLEPSCTVSSADVDWNAEFSATCLNFSGLSLSLPHNQSLRASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAARCDLDLQADCNCALESWHDIRRDNCSGQKPLLCWDTTSSQHNLSAFLEVSCAPGLASATIGAVVVSGCLLLGLAIAGPVLAWRLWRCRVARSRELNKPWAAQDGPKPGLGLQPRYGSRSAPKPQVAVPSCPSTPDYENMFVGQPAAEHQWDEQGAHPSEDNDFYINYKDIDLASQPVYCNLQSLGQAPMDEEEYVIPGH
The following text describes a protein:
Function:
Synthetic BmK-YA activates human opioid receptors in vitro, with highest activity on the delta-type/OPRD1 receptor (EC(50)=2.5 uM) and lower activity on mu-type/OPRM1 and kappa-type/OPRK1 receptors (EC(50)=17 uM and 30 uM, respectively).
Miscellaneous:
MISCELLANEOUS: Four additional, similar peptides (containing a substitution of Tyr-4 to His-4) are predicted from this sequence: however, there is no evidence that they exist in vivo and the synthetic peptide has no known function.
Subcellular Localization:
Secreted.
Sequence:
MIFHQFYSILILCLIFPNQVVQSDKERQDWIPSDYGGYMNPAGRSDEERQDWIPSDYGGHMNPAGRSDEERQDWIPSDYGGHMNPAGRSNEERQDWIPSDYGGYMNPAGRSDEERQDWIPSDYGGHMNPAGRSNEERQDWIPSDYGGYMNPAGRSDEERQDWIPSDYGGHMNPAGRSDEERQDWIPSDYGGYMNPAGRSD
The following text describes a protein:
Function:
Venom protein with unknown function. Does not induce paralysis when a high dose is administered by intrathoracic injection into the blowfly Lucilia caesar.
Subcellular Localization:
Secreted.
Sequence:
MKIVKLITIFAMIATLMVTVTNGEAVFLTPDQIKAMIKRHG
The following text describes a protein:
Function:
GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.
Sequence:
MDTDTATAMGALEEAHLAAAACACEEEEESDYIGFLAGEAAAGDAVEPAVRALLLGLGEDDRREGLLRTPKRVAKAFRDGTRGYRQKVKDIVQGALFPEVGVDKRTGSAGGTGGQVVVRDIELFSYCESCLLPFSIQCHVGYVPSGGRVVGLSKLSRVSDVFAKRLQNPQRLANEICGALHASIQPAGVAVALQCWHIPLPENLECKTLEGWIRTSHSSRSGVFEGESSTFWSDFLALVKLRGIDVEAKDRTVSIPWCPLRSHEVPLSNGLCKKNSTNGMVSAVTSMLLSLGEDPLRKELLGTPQRYVQWLMKFKACNLLDVKLNGFTLSNVSLYERTGGGTTDHGAIRSELHLPFCAQCEHHLLPFYGVVHIGYFGNGSGEGIDRSHFQALVHFYGCKLQVQERMTRQIAEAVYSVSHNGAMVVVEANHICMISRGIEKIRSNTATIAVLGQFLADPSAKACFLQNVLDSVGSAV
The following text describes a protein:
Function:
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
Sequence:
MNRINQLFNSNKKDILSIYFCAGNPTLDGTVNVIRTLEKHGVSMIEVGIPFSDPMADGIVIQNAATQALRNGMSLKILFEQLRNIRQEVSIPLVFMGYLNPIMQFGFENFCRKCVECGIDGVIIPDLPFRDYQDHYRIIAERYGIKVIMLITPETSEERVREIDAHTDGFIYMVSSAATTGAQQDFNEQKRAYFKKIEDMNLRNPLMVGFGISNKATFQAACEHASGAIIGSRFVTLLEEEKDPEKAILKLKDALK
The following text describes a protein:
Function:
Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes.
Subcellular Localization:
Cytoplasm.
Sequence:
MENRIDRIKKQLHSSSYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLTELKVVDKINFGDGVSRYDLRKEGAAHFHHHLVCMECGAVDEIEEDLLEDVEEIIERDWKFKIKDHRLTFHGICHRCNGKETE
The following text describes a protein:
Function:
May act as an auxiliary subunit of the unc-2 voltage-gated calcium channel which appears to trigger calcium-activated signaling pathways that control the serotonin response. Inhibiting serotonin sensitivity of the vulval muscles results in egg laying defects. May act in both neurons and muscle cells to enhance motor activity as it is required for coordinated movement. Has a role in neural depolarization-induced calcium influx and pharyngeal pumping. Involved in restricting the expression of the putative olfactory receptor str-2 to only one of the two AWC neurons.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MRVVHLLVVLATYVSTTSSFNKESIKECAKVLSEHMKETFSKISHETILKQNYEKLVEEEQFDPRAELKKSKHRIEDYLKVRSQFAYKAKISLEARSVRNDSTVNDPQSKSFIRFMSAKQGNDGTTIYESNHLGKRLKVNETKSFNLTQNANFYTLPTSSVSSAVHIPTPLYDRNEDLLRKIDWSDIDAVYRTNREETKDLAFQLFCSEAGYMRYYPAASWFWDNQDEHLDLFDCRNTEWYINSATNSKNVLIMLDMSGSMLGQRYEVAKQTTEAILETLSHNDYFNIMTFSKNTFLLDGCNGTNGLLQATMRNKKALRRKMDTYQSEGKAEYEKALPLAFSVLLDLKGSYALYTKEEMSMMSANATNEYQFHLELPEHVLAATKQYIDSINNGGGDNNRGACENVIMLITDGAPNAYKKIFDMYNADKKVRVFTFLVGDEAIDFNEVREMACNNRGYMVHVANMADVDEKIHHYIRRMSRVVGRHYKESGQLSWWTGVYRERLYLPRPEIFAEPVPITNQSFAVMNKMASRRKIRLQKSEARSRMFVTTVSYPVIVNETFMGVAAVNIPLTEVAQKSHPANIGSKSYFFMLDQNGFVMTHPQLRPIDPFTKYHKQNYNNMDLLELEVGQNQNVRSSQKSQAVSDLVCESGANYAECVDDLRKAVRKMIIDCDNSDVQQLDVLYATELLDRVYPQTNTYYAECINHANFVLGLAVAKGDDYRVVKKQKKYDFGRVKMDWMGDKRWRLHPHWRYCFLNDTDTHMSKEEAFEIYAQQMSDSGKAPLLCEYRRNLVEKLLLDMEATSNLIDSWDTQFNFMKNNLIHLAFFATPSGMIRYYNLTLQDYDYIDPYWSIFEHIGHLLSIEHAQESYNHFITDLNRKSTDDRYYRRAVRMKDTIMFDVSNNSKIWYKSETQLTGYGLNENLTMLGQAFKAIYLDKAVLGVSGFEFAYDHVVDTMAEHGCPASDDRKWCVLLDEHAYVFFSNQNDISYEDYLVGKGKHISQYFGGLNRIAQRAMALLVENKFYTKLTYTDNQAVCKAEKVVTTSGNRLRPFYPIFRFLMQTFNFMVRLASQISGGFLIWLPNIQFTEAYTASFHEGTDVYPCPKQSSFYFSNKDGKNRPGTTHLVNGNRSERPCKMNAKCSVKMEASFVDGTNLVMVWITQDKASENCYDESECSMEISNQVPFGFEEVKNEETCEENEKRKSKANDVCYSIDDDDSENERRPCSTSPTIVSIFQILFGVFLHFCIF
The following text describes a protein:
Function:
Cleaves the N-terminal amino acid of tripeptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MTLVDRFLKYVSFDTQSDESTGLTPSTPKQMVFAEYLKTELESLGLEDITLDEHGYLFATLPANIDKKVPTIGFIAHMDTSPDMTGKDVTPRIVKGYDGTDIVLCAEENIILSPAQFPELLDHKGEDLIVTNGKTLLGADDKAGIAEIVSAIVYLKEHPEIKHGKIRIGFNPDEEIGEGAHKFDVGKFGCEWAYTMDGGEVGELEFENFNAAAAKITFKGRNVHPGYAKNKMINSIRVANQFIAMLPSTETPEQTEGYEGFYHLISIQGDVEQSTVSYIIRDHDRAKFEKRKEEIKRLVAQVNTEYGEGTATLELRDQYYNMREKIEPVMHIIDTAFAAMEAVGVKPNVKPIRGGTDGAQLSFKGLPCPNIFAGGLNFHGRYEFVPIQNMEKAMNVIVKIAELVASK
The following text describes a protein:
Function:
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides. Has a low but significant activity for the purine nucleoside xanthosine.
Sequence:
MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAESTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH
The following text describes a protein:
Function:
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Sequence:
MNNYQEFKIIDNIAKLIESSFGIHGKLKLISQVFDHKNDEGENDNVVNSTQKIIFTNDGLLIFKSLNNDSPYYKIILQQSNYIKNRFGCGVSQYIILTNNILKRSIKLINNKGSSSSSTSTFSINQILNIFQECRLFIKNNFNERFIINLKDEIFSSSGGKNDQLLESIIKTNLSKNILSIYFKRISKIFKKLIKILPNLDKNKIKIKTIISSNEDHNNNNEDEDEKKEEEDDDDNDEIEIKLLNGILIKSKFSFAGRDKLIKVIENPKILLLDYEIELKHQKEFANIEISNVNDYLEFINAEKSLISKQLENIYNLNINLILNKKVIGDLAIQEFVKISSQNQNNNNKINCIGSINNINEFEFIKKSIGGNTQSSLQNLSLDSSFYGTCKKYKQIIIGKKSYELFEGCQFSDTQTIILKGSSKKFLKEAKLGLESLLTIFRSIIIDDDFKFVGSSSNFEFIIINLLNELIKNKQNSSSSSSSSLSTNLIKEVLIIKSLQKSIKDIIKLLLLNSDLNLDLIDQLFQINNNNNNSCINIEENKIGDILDLNLFEPKSMKLSILNSSIETSCILLKTITT