lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MELPNYSRQLMQQLHALRKDGHFCDCTILIGQALHRAHKLVLAASSLLFKSLMEGSDTISIDSSVVTSQEFSCLLEMIYTGKLPPGKHNFTRIIAAADSLQMFDVAVSCKNILNDLIKPPATTEPPADATDLALGGSEHTSSPVVAVPSSSEAAEVFLDPTPAASEEAMEGGSAEATCEKTGNPLMDEEENPAKNGDSAIPRVWESSVENSPPCKRGRLALTVTKESQKKKSSRHFGKESEEYLEFLQQNKNKIAGAIGNVQPVINAVEKWEEISSVEKLVILDCCKGEPDVTDIFHSLLNYVVSKKLSTRTLLTLLEALREFCPDLATVLENPLQGEQNVERDAHQVPDEKPASRLLADHAEELIVSISHLRPIIEVLDNMKEDFLTETEKQTVFQCCQDVCTREAIQSLLNKVKVEKVLEESSFLKLLHAVKSSFPVLQQLLDTTVAEGTTFQSKEDRGQEEYETDLLRRYHQRLSESICDPQPLLESLAAADDVSAEDQKWMKQVLEEEASPRCLDKLLSLAVEKGSVQVLAVWKLLVRTEIPALSLLIQDIRKDPEADRLIHSVLDLESQLLEILSRHKDLITETISSLGALLDSVTGEPECPSGDAIEFIKNCSTQVNLNESVKTLLDKILHEKSMAAQPFCKLVSLNKGFFPSLRPLTDELEQAGKIKNKNNKKKMFIFCASGHLPASSKRVADRKSKLEEPQTGEGEKDPGDGVEKKGGKKGGAKQSFPCEWCGKTFEFKCRMEVHRKRCRLSEQTQLKCPQCPEKMSTPKALQQHLAKSHGSPPRKRKKRRHEPVTCDICGKSFAHQSGMLYHKRTDHFDEKPYSCEECGAKFAANSTLKNHMRLHTGEKPFFCKHCDMTFTQAAALAYHYKKKHSEGKMYACQYCEAVFAQSIELTRHVRTHTGDKPYVCRECGKGFSQANGLSMHLQTFHNIDDPYDCQKCRMSFSCLEEHRKHIQESHPKEFHPCVVCGKIFNAAALLEKHMVIHVGGKPYSCEICNKAYQQVSGLWYHNRTNHPEVFAGQSHRSVKISQFQCSSCDKTFPSSETLSKHEKAMHPDVKLFKCQDCEDVFPDAELLKTHTKEKHEGAQLFNCLYCPSSFQTTAELQQHLCVQHFNQQGEAFGCGHCDLIFPSQQELQEHFLSQHPAELQSSSEASSAQMVKVIRAAEQPGAAEQMITLEQSQVGSPQVYVALADSQNSTSGSEIVAVNVEDLLDGTVTFICEDTQ
The following text describes a protein:
Function:
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
Subcellular Localization:
Lysosome.
Sequence:
MIRWHALAWPSDSFQSNVKYQTKYFKQRLDHFSPADDRKFQQRYLISQKYWKKGSPIFFYTGNEGDITWFAKNTGFMWDIAPEFNAMLIFVEHRYYGKTLPFGKDSFKDKEHLAYLSSEQALADFAQFIVDFKAETHGTQNSSVIAFGGSYGGMLTAWLRIKYPNIVDGAIAASAPIWQLEGLTPCDRFSSIVTNTFKLAYPECPKNIRNSWKVIRKLGSTKSGRHTLSTTLKLCNPLKSPSDVDALVNWLSSIWVNLAEVDYPYPANFLEPLPAKPVKAVCASLQKPLANDTLLIRGIAKGLNVYFNHTGNSKCFNTDQDATSHLGIAGWNFQSCTEMVLPVCMDGVHDMFEPTPFNLTAMAAICKEQYGVRTRPFWAQTLYGGKRIKAASNIVFSNGNLDPWSGGGVLKSLSKSLVAIVIEGGAHHLDLRHANKDDPATVKHARKIEKMHIAKWIKEASNE
The following text describes a protein:
Function:
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MQCYTELISPTGVTHALAVPFLSATANNLIVARTSLLQIFSLRDVSLSALDTEVRPAQHRQETCKLVLEREYQLPGTVTDICRVKILKTKSGGDAVLVAFRDAKLSLVEWDPERYGLSTISIHYYERDDMTRSPWASDLSTCGSILSADPGSRCAIFQFGARSLAIIPFHQPGDDLVMDDFGSEPDYENRVEGNSRSHEAKDKDAAEYQTPYASSFVLPLTALDPSVIHPISLAFLYEYREPTFGILYSQVATSHALLHERKDVVFYTVITLDLEQRASTTLLSVTRLPSDLFKVVALPPPVGGSLLIGSNELVHIDQAGKTNAVGVNEFSRQASSFSMTDQSDLALRLENCVVERFSDDNGDLLLALSTGVFALVSFKLDGRSVSGISVRPLSGPSKEFLASTASSSAFLGNGKVFFGSESADSVLLGWSSASSATKKSFSGSTSNDESEDDAYEDDLYSSAPAAMTDNPQNQPSNSSVAAFGDLRIHDRLSSPGPIRDIVLGRSSEASSRDTKDGVLELVAAQGSDEGGTMVIMKREVDPYLVASMAADTANSLWTVSLLPDNNDQKRDYVILSKQEKPDKEESEVFVLEDKLRPITAPEFNPNHELTVEIGTLASKSRVIQVLRNEVRSYDAVWDEDDSDERVAVNATLVDPYLAIIRDDSTLLLLQADDSGDLDEVTLSEDVVSQKWLSACFYSDNAGFFTAPFASILFLLNQDHQLYVYRLPDFAVISVIEGVGCLPPILSTEPPKRSTTRENVLQIAVVELGDSYSSLPFLILRTENDDLVVYKPFFTNSKELTGLRFLKEANHTLPKTPNTTDELQSEMKPLRILPNIAGCSSIFMPGPSAGFIFRASTTSPHFIRLRGGFIKGLGCFDSPDKGFAYLDSHGLHLAKLPEGTQLGYPWIMRTVPIGQQIDKLTYVSASDTYVLGTCQRCEFRLPEDDELHPEWRNEEISFLPEVNQSSLKVVSPKTWSVIDSYPLEPAEHIMVMKTMSLEVSENTHERRDMIVVGTSLARGEDIPSRGCIYVFEVIEVVPDPEQPETNRRLKLIGKEPVKGAVTALSEIGGQGFLIAAQGQKSMVRGLKEDGSLLPVAFMDMQCFVSVIKELKGTGMCIFGDAVKGLWFAGYSEEPYKMSLFAKDLDYLEVLAADFLPDGNKLFIVVADSDCNLYVLQYDPEDPNSSNGDKLLNRSKFHTGNFASTVTLLPRTLVSSERAMSGSDKMDIDNTAPLHQVLVTSHNGSIGLVTCVPEESYRRLSALQSQLTNTLEHPCGLNPRAYRAVESDASAGRGMLDSNLLLQYLDMSKQRKAEIAGRVGATEWEIRADLEAISGGGLGYL
The following text describes a protein:
Function:
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
Sequence:
MRPDGPRDPVAGPDSGPEPPYPVRLSGPVIKGFGRGSKELGIPTANIPAEGLEEYPDLQVGVYYGVVALDPAKFQYQEGQGSTSTSSTGGAEAAVLPAVLSIGYNPFYKNKTKSIEIHIMPPLSSPSPTADGAGEVKFHKLPDFYGTQLKLLILGYIRPEYDYVSLEALIEDIRVDCEVARKSLQRPAYACYIDGDEKECSDVVREQRRWLVTF
The following text describes a protein:
Function:
Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MTAKAQTKEKMGSCFRLCERDASSSLRLTRNSDLKRINGFCTKPQESPKAPSHTYSHRVPLHKPTDWERKILIWSGRFKKEDEIPETVSFEMLDAAKNKIRVKISYLMIALTVAGCILMVIEGKKAVKRNESLTSLNLEKKARLREEAAMKAKTE
The following text describes a protein:
Function:
Member of the two-component regulatory system BasS/BasR. Autophosphorylates and activates BasR by phosphorylation. Plays a role in the adaptation of the organism to the host environment, in particular to neutrophils, and therefore it plays a role in virulence as well.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MRFQRRAMTLRQRLMLTIGLILLVFQLISTFWLWHESTEQIQLFEQALRDNRNNDRHIMHEIREAVASLIVPGVFMVSLTLLICYQAVRRITRPLAELQKELEARTADNLAPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSGVRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVILPSYDELNTMLETRQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHITIHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGLGLSIVSRITQLHQGQFFLQNRTERTGTRAWVLLKKA
The following text describes a protein:
Function:
Plays a role in nonsense-mediated mRNA decay.
Subcellular Localization:
Nucleus.
Sequence:
MSNRGISCNEPVSNKLYEQLYRDGVTKLQRLKELIQGHNREKNACNGVEKGASGSDGKREGTQLSKDVTVSSEGHDLDELFALSKKITKDFGQIIREDLEFSNRKELLTLLWGKVHYRLVVFTKKLVWQKSDGNNISRTATRVRGSGSRRSSPGANTAVANRGIVKQFTRSIALHVRYLDECVQFYQQLIREMVLAFEVQELQPLLEWLQLKRDGDNNGENGTTAAGKTVSLKRGSTFAHNKKATKTGTYSSVAKCAASISARKQFYSSTVQKNQLVWTVYRSLISLGDLCRYLAQAKSPKQPDYGAAVEFYRLAGYVMPDVGIHFHQLGLIAASAPKSNVLQSVAYFYAATTSLVRSGVSSAYDNLGLALRKFLRECDSQVTNSSAPKQEVHRGKTKEPSVVQQFLKLHANYECNSENDALPPKPNRLLGQLRSMLNNHQLPEKQLLAMSFCNIAVLRLSTEPSATAGLNLSETSTKAPELVSFMEQFILSFFMTLLDVANEKLPLQSLTAAAQSSSEQTSENPVFSRLLSSIALLLSFMARHPKWAPKQLISQAKRLHNRLSFFWENSGRSPPTANAVKLFTASEPLLLPFICQPLPLGAYPSASTAEIEFLSSVLISYYRPSEHHGNSISKCSYDTCLDAVYLLLQGVVMESANPNASGPVLNLPTCAPLKTVPSQPWNSLQTSSTSLINGSSSPINGIGTEFAWNFSALQTGDASSVTTSPSRLNPFQTDSVLPSLQLGRMVDSLVGPAPEVRAQPTGGSMHSLQFRVSTPAISCSPTFGSVSSLPSRVTSPPSPRSDSNGVEENEDGGLSDGEHVLFRPIMADSASSSDEDDDDLTPSEDAGTPISHPLTDYSSTSLVETLKSSNQHTLLSSMLRNALRIHASNS
The following text describes a protein:
Function:
Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion. Plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU. Probably involved in the assembly of the membrane components of the uniporter complex (uniplex).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MDCGSVGGQRTQRLPGRQRLLFLPVGLSGRPGGSETSARRCLSALSDGLGALRPRAPAARGGVSRASPLLLLLLVPSPRLAAAAPRRQLGDWERSRLGYAAPPAGRSSAWRCSPGVAAAAGALPQYHGPAPALVSCRRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGFYRLWI
The following text describes a protein:
Function:
May be involved in hepatocellular function and development.
Subcellular Localization:
Nucleus envelope.
Sequence:
MPPFLLLTCLFITGTSVSPVALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWYHFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLESDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDIEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVSNGTHVNILFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESLVESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQTLTGGPIHIDWED
The following text describes a protein:
Function:
Architectural component of nuclear structure that plays different roles in controlling nuclear size and morphology.
Subcellular Localization:
Nucleus matrix. Nucleus lamina. Note=Localizes at the nuclear periphery.
Sequence:
MGRVEDMGLNAKLMKLETELFDYQYNMGLLLIEKKEWTSKFEELQQVYTETKDALKQEQEAHLIAISDAEKREENLTKALGVEKQCVLDLEKALRDMRSDYAEIKFTSDSKLAEASALITKVEEKSLEVESKLHSADAKLAELSRKGSDIERKSHELEARESALRRERLALNAEREALTDNISRQREDLREWERKLQEDEERLAEVRRLLNQREERANENDRLYQQKQSELDGEQKKIEIIMVSLKNKEDDISSRIAKLNIKEKEADAVKHSLEVKEKDLTEFEQKLNAREQSEIQKLLDEHKAILEVKKQSFEMEMDKRKNDFENDLQNRAVEVEKKEVEVKHLEAKLAKREHALDQKHEKLKEKEQYLASKLQDLNEREKSMKLEENKIEDERNQLLSDKQEMLCLKAEIEKDRASTEEQRLKLSEEIERLKITEEERLELARLQSELKQEIENCRHQRELLLKEEDELKQEKMRFEKEWEDLDERRTALMKDLKDITVQKENFEKLKHSEEDRLNNKKLDTESYVQKELDALRLTKDSFAATMEHEKAVLAERTSSEKKQMLNDFELWKRELETKLFNEREDMENALRLREKQFDEEREKELNNINYIKEVISKEREDIKLERSRIAKEKQEILMHQKHLDEQHVVMQKDIGQLVSLSEKLKDQREQFFKERECFIRFVESQKSCKNCGEMTSEFVVSDLQSLAELENLKALSVPQLAENYLRQDLQGTPDKNLSTVTPGAVGLGSPASGGTKSWLQKCTSKIFIFSASKKNNSPDQNTSRRLHVEASPNKLLNTEVIPELPSGVAGETLEMQNMQVSNSNREMESNLNLSGTEQSNIDSKALDVEDSQQSDVRAGNRKPGKRAKGRVRRKRSAKEVAEEAKTVLADPIELNENEHSNGLASAYTNESRGDSSLVGKRTRNSRKRNPSQPSQSAAGDVGADSEGHSDSVTAGGRQKRRRKVVPAVQAPTGRYNLRRHKTAAPLVANGALSDPNKGKEKEIDDGGGIGEEIPDEVDGNTHLVQVTTLKKRINVVNEFSSAGFHGINATSESQDRDAANQLVSDTMLSEEVNGTPEQSRGYQNQGDTSGAEGEDEDGDEVEHPGEVSMRKKVWKFLTT
The following text describes a protein:
Function:
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
Sequence:
MALLASVGKYIHYIHPEIAHRLGALLFSIPLPSCKCERSWEIGGVKVCGPVGVAAGLDKTGLYSRFLSFFCPGFIVVGSTLPRARRGNRPPRAARLRPYSMVNAMGLNSPGIAKVVSRLRGLRYPLFISIAGFSAEDFAVQLLYLQRHFKPDAVEINISSPTYRGFWRDAPTLVKTEFPVFVKVGPSADIRSVVRRVREVGWGLVVTNTLPVEDPRLSVGRGGLSGLLLYKYGFKLLERVRRLAGKDVPIIYSGGLYTCGQLREVLKLADAAEVLTSILYFTPYVLKLLNRCPDIRL
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Sequence:
MANKAATASIIAAVGVVAVIGTIAAVTASKKAHDGSDGGSAMSTSIKLSALCSSTLYPTKCEKSLSPVVNETSDPEEVLKASLQVAMDEVAAAFARYAYVGKGATDGTVTKSAIGECKKLLDDAVGDLKDMAGLRADQVVSHVKDLRTWLSGVMTYIYTCADGFDKPELKEAMDKLLQNSTELSSNALAIVTRVGEFLKGQESAQKNGTSIGAGSRRLLGWPAIISDAETRRRRLLEISGKLDEIASVRDASRRLLVETMDEIDQMSHDGSRRLDNFVFGDHFSNLTDIPSQSKESDFVRRRLLSMSFDDASSKATDDSDRDAVRRRRRLLSAQLESIADMSAQLNRRLLAMDVPTGDDMAGKKRQRLSNSLVMINDAAAEAQAQLEEIDDNCGNDFTPPEEEERRALTSDVIGTIEDLDHKHHQRKMLTTDVVGTIDDLDHKHHHRRKLLTFPEWVPAQARRLLQIPGLQKPNAVVAADGSGNFKTITEAVNAAPKKSTARFVIYVKAGEYKEYVTIPKDVTNVFMFGDGPTKTRVVGDKSNKGGFATIATRTFSAEGNGFICKSMGFVNTAGPDGHQAVALHVQGDMSVFFNCRFEGYQDTLYVHANRQFFRNCEVLGTIDFIFGNSAALFQNCLMTVRKPMESQANMVTAHGRTDPNMPTGIVLQGCKIVPEQELFPARLTIASYLGRPWKEYSRTVVMESTIGDLIRPEGWSEWMGDLGLKTLYYAEYNNNGPGAGTSKRVAWPGYRVIGQAEATHFTAGVFIDGISWLQSTGTPNVMGFIK
The following text describes a protein:
Function:
Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation.
Sequence:
MFRGLGSWFGLEQPPAGGEPWREPPPQQGEEDEREEEEEEEEERERQSHGDQEPLLHQARGLGNYLFNFASAATKKISESVAETAQTIKKTVEEGKIDGIIDKTIIGDFQKEQKKFVQEQHTKKSEAAVPPWVDSNEEETIQQQILALSADKRNFLRDPPAGVQFHFDFDQMYPVAMVMLQEDELLNRMRFDLVPKHVKEEVFWRNYFYRVSLIKQSAQLTALAAQQQAVGKEEKNSGREGDLQLTETVRPKTPPVAIKSQLKPQEDEEEISTSPGVSEFVSDAFDACDLNREDLRKEMEQLVLDKKEEEITVLEEEPADWEKELQQELQEYEVVTESEKRDEKWDKEIEEMLQEGN
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
Sequence:
MCSLLTKQAEFGGDPLGNKRACASQLPQTSPSLEQDTMTSQSQGIQQLLQAEKRAKDKLDEAKKRKGKRLRQAKEEAVAETDQYRMQREKEFRLKQSKIMGSQSHLSDELEEQTLEKIKELSGSYHKCMDSVIKQLLSMVCEMKPEVHVNYRATS
The following text describes a protein:
Function:
Plays an important role in chromosome segregation during meiosis I by allowing meiotic rec8 to establish cohesion at the centromeric central core and thereby promote the side-by-side structure of kinetochores at meiosis I. Enables monopolar attachment during meiosis I. Required to facilitate kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Acts in collaboration with plo1.
Subcellular Localization:
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes to the centromere. Does not require rec8 for centromeric localization but instead cnp3.
Sequence:
MAINNENELEYKLIKKNKNPKISNSKKKNSTRPALQDKTNQTLPIHQNQAFSNILPSDFSIIKTPETKTADDFPVNGYEGLNILKFDLELFYKLKPVATSTPKSCMRTGSNLFLNETVKHVPDERLVSNIKNTQTKDSITRDSAYYHRKTMTESIIKTLAAFDAEVDEIILF
The following text describes a protein:
Function:
May down-regulate transcription mediated by NF-kappa-B and the serum response element.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTRWARVSTTCNKRPLPATSWEDMKKGSFEGTSQNLPKHKQLEANRLSLKNDASQAKHKKKKKKEYLNEDVNGFMEYLRQNSQMVHNGQIVATDSEEVREEIAVALKKDSRREGRRLKRQAAKKNAMVCFHCRKPGHGIADCPAALENQDMGTGICYRCGSTEHEITKCKAKVDPALGEFPFAKCFVCGEMGHLSRSCPDNPKGLYADGGGCKLCGSVEHLKKDCPESQNSERMVTVGRWAKGMSADYEEILDAPKPQKPKTKIPKVVNF
The following text describes a protein:
Function:
Functions in trans to edit the amino acid moiety from incorrectly charged Ala-tRNA(Pro). Has weak activity on correctly charged tRNA(Ala), tRNA(Gly) as well as tRNA(Cys), tRNA(Met), tRNA(Pro), tRNA(Ser) and tRNA(Leu).
Subcellular Localization:
Cytoplasm.
Sequence:
MDMDAKQAVIAKLDELKINYTLIEHDPVYTIEEMEKIDIENVDYIVKNLFLRDAKGRQHYLVVADKDQKIDLKTLQDKIGSTKLSFASEDRLQKYLKLTKGAVSPFGVLNDETAEVEVVFDKNLVGRSCVAVHPNDNSATVVLSYEDLEKIVKANGNTFKAIEL
The following text describes a protein:
Function:
Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTGWIVLPISLTVFSIPGIWIVYAMAVMNHHVCPVENWTYNLTCTDDNTKAGTPKSCCTLEDVPLISKCGTYPPESCLFSLIGNVGAFMVVIICLLRYSQVIEVSQRSWLNTTALIAGCTNAAGLVMVGNFQVDYAKSLHYIGAGVAFPAGLLFVCLSSILSYQIAASALDYWLGHLRVSLTIVALISLVLSGVFFIQESFLMQHLAAICEWIFVLDILVFYGTFAYEFGSVSTDTMMAALQSSSARSCKSPGSSSTSTHLHCNAERIAMI
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit; With S5 and S12 plays an important role in translational accuracy.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MRKLKFHEQKLLKKTNFLEYKREGGHREALVTQRYRLVERDDYKKYNGICLMVQKLVNIIKQMDPRDPFRIEMTDMLLDKLYNMGVIPTKKSLLKCENLSASAFCRRRLATVMVKLKFAEHLKEAVTYIEQGHVRVGPETVTDPAFLVTRNMEDFITWVDSSKIKRKVMEYNDALDDYDAMF
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Subcellular Localization:
Mitochondrion.
Sequence:
MRLHLLLPPPPLPPLSLFPLLPPPPLLSSPSLLPPRSSFPSSCFSSPSSPPSFSSPSSLPFPSSSLLLLPSSSPLPPSSPFPSSSLLLLLPSSSLLLLLSSSLLLLPSSSLLLLLSLLPSSSSPFIPLPRFLPPPSLPVLPPPSLPVLPPPSLPVLPPPRPPSSLPSPPSPSVLLALAAACSAGPARQGVAVPGGAGPRGARVRVPGRRGALWVWSAMAARVLWARGLWACARRLPAARQDPTPTPAPTPAPTRTLSGGPAIAVTPRLGMAHANAGYAQISSTFVQWSRQYSDLPPLTLESIKERVLYVLKLYDKIDPEKLSVSSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE
The following text describes a protein:
Function:
Catalyzes the hydrolysis of the amide bond of streptolidine lactam, thereby conferring streptothricin (ST) resistance. Can hydrolyze streptothricin-F and streptothricin-D. However, this strain is believed to be a ST nonproducer, which raises the possibility that its true role may not be its involvement in self-resistance to STs. May catalyze the hydrolysis of naturally occurring cyclic amide compounds that are structurally related to STs.
Sequence:
MIRPDRCPWQPCPSGRYLSRPSGRVPRSTMMTPMTAMPAVTAMPPETAAPPETAAPARPLRPVQALLVVDVQTAFVSGAEAVPEAARVLDRTRGLLARARTAGALVVHLQNDGAPGAVDAPHTPGWELHLPVEPGPREHVVRKTEDDGFADTGLGALLDAAGVTELAVCGVLSEMCVAATARTALELGHRVVLPHDAHATYDIPAAPDISDTVPAAMSSRAAEWALGDEVEIVPRAAAVPFVAPPLAPAPEAPAAAAAPAAGTGLSPAGPPPAPAR
The following text describes a protein:
Function:
May be involved in the synthesis of homogalacturonan. Required for normal cell adhesion and plant development.
Miscellaneous:
MISCELLANEOUS: Co-expressed with the galacturonosyltransferase GAUT8/QUASIMODO1.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MSMPLQRGISGVRVSDSSDDLRDSQMKDKTERARSTENNNLTLRFPFGFLFSNQSSSKHGGGGENGFSADPYSARSRHRLMLLFLKISLVLIVVIALAGSFWWTISISTSSRGHVYHNYRRLQEQLVSDLWDIGEISLGPNRWKELEYCNIESENFVPCFNVSENLALGYSNGDENDRFCGPGSKQECLELPPVKYRVPLRWPTGKDIIWHSNVKITAQEVVSSGSITKRMMMMEDDQISFRSASPMSDEVEDYSHQIAEMIGIKKDNFIEAGVRTILDIGCGYGSFGAHLLSKQILTMCIANYEASGSQVQLTLERGLPAMIGSFISKQLPYPSLSFDMLHCLRCGIDWDQKDGLLLVEIDRVLKPGGYFVWTSPLTNPRNKDHLKRWNFVHDFAESICWTLLNQQDETVVWKKTINTKCYSSRKPGVGPSVCTKGHDVESPYYRPLQMCIGGTRSRRWIPIEGRTRWPSRSNMNKTELSLYGLHPEVLGEDAENWKITVREYWSLLSPLIFSDHPKRPGDEDPSPPYNMLRNVLDMNAQFGGLNSALLEARKSVWVMNVVPTAGPNHLPMILDRGFVGVLHNWCEPFPTYPRTYDLVHADNLLSLQTSQPRKTCLLIDIFTEIDRLLRPEGWVIIRDTAQLVEKARETITQLKWEARVIEVESSSEQRLLICQKPFTKRQSI
The following text describes a protein:
Function:
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
Subcellular Localization:
Periplasm.
Sequence:
MRTQRLKKLALVCALGFACITTAQAAERIAFIPKLVGVGFFTSGGKGAVDAGKALGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIVVSAVSPDGLCPALKRAMQRGVKILTWDSDTKPECRSVYINQGTPNQLGSMLVDMAANQVKKEQAKVAFFYSSPTVTDQNQWVNEAKKKIQQEHPGWEIVTTQFGYNDATKSLQTAEGILKAYADLDAIIAPDANALPAAAQAAENLKRANVAIVGFSTPNVMRPYVERGTVKEFGLWDVVNQGKISVYVANEMLKKGDLNVGDKIDIPNIGVVEVSPNRVQGYDYEAKGNGIVLLPQRVIFTKENISKYDF
The following text describes a protein:
Function:
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MFDFIKYKYVSICISLALIVFGFSYTYAVHGGFANSLDFNGGLRTVVEFDQNMDRKKLENYFAENKIEAVLLLLDKEKHHYQIDIGLGSVDSILLKYREKNGLKPTDKVELSGIDALISILIADFRIDKSNILSANQVGAIVGGELSSTGTTLLGLTMAIILAYISFRFQFKFALGAILALTHDLILTVAFIGFFQIKPSVPIIAALLTLLGYSINDTIVVFDRIRENSAGNLNQTFGQTINSAINQTLGRTFNTSFATLISIVAIIIGGATELFDFAYVLTFGIVIGTYSSIFIAAPLVDIYDQVIRKARD
The following text describes a protein:
Function:
Component of a FANCM-MHF complex that promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork (Probable). FANCM-MHF promotes non-crossover recombination.
Subcellular Localization:
Nucleus.
Sequence:
MMEEERFKAEIFHVTQEVCNRTASELTESESRNVIVDELFCVGVTEMVWEQIRVLAKDIEAFAEHAGRKTVQPQDVLLCCRRNEGLYEIINNFHKESIKSKKKKKENSTT
The following text describes a protein:
Function:
Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity).
Miscellaneous:
MISCELLANEOUS: Tyrosine phosphatase activity has not been demonstrated for this protein to date.
Subcellular Localization:
Cytoplasm, cytoskeleton. Nucleus.
Sequence:
MALVTVSRSPPGSGASTPVGPWDQAVQRRSRLQRRQSFAVLRGAVLGLQDGGDNDDAAEASSEPTEKAPSEEELHGDQTDFGQGSQSPQKQEEQRQHLHLMVQLLRPQDDIRLAAQLEAPRPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSSPSCTLGLVLPLWSDTQVYLDGDGGFSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQERLNSEQSCLNEWTAMADLESLRPPSAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVTSKEIRQALELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSHVWEQKVGGVSPEEHPAPEVSTPFPPLPPEPEGGGEEKVVGMEESQAAPKEEPGPRPRINLRGVMRSISLLEPSLELESTSETSDMPEVFSSHESSHEEPLQPFPQLARTKGGQQVDRGPQPALKSRQSVVTLQGSAVVANRTQAFQEQEQGQGQGQGEPCISSTPRFRKVVRQASVHDSGEEGEA
The following text describes a protein:
Function:
May act as a lysosomal receptor (By similarity). May be involved in macropinocytosis and fluid phase exocytosis.
Subcellular Localization:
Lysosome membrane; Multi-pass membrane protein. Note=Localizes to membranes of endolysosomal vesicles and macropinosomes.
Sequence:
MKHIGRIVSFPIGLVLIAVGIIIFVVVNRTIKDEFKKAAVVIPDNGAEEIVDPWVRFIGNEGDPNNVRTYTFMAYNLTNPIETMQGHLPKYQEVGPYSYNYIYERINANLYEDDEKLSFKLWKRYFPIVADGYRDPTKDTIYHFNLVYGAAVKQAGSEVALSVALTAAAMGKIITGLTDPSFKVKAGFAAAPTVTAGAFSNLLTAAGNDPATACGLWQTSTSSSTPLVPFSVPIIAGSPSDISQAQCQALFDPSNKFSLTDPTNVGVYLLNPAGSKAALLASPFGLTSVQADLIMKYQLALTSTFVPTTLVSRFAECSDPKTCTNNPLYFGLLQWAKNPSLLGQSVFAIPNSGVPAAPEFGIYTSSELSLTKAGSLFLNTSTINLITPTSIGTILVYGQKLKADPTSIPPALYAPFSSGEFDAIVKYTGYIMAAFVDGDIIKNQIFKDYQGGPIVKHTVHDFLFNSTDPLLKLMYPDTPSAWVSSPLDNIQDVKVANATLHTDEIYTGVGDIDLVSSPITFEGEEELNYNKKIKVSGSFAEQLPPSYLSKDPEAPVNVFTDEFARSLSFRKEVGGNFGGIPYYRYRINESNWEINPDYFQTIPYLLNLTSIKSGAPAYLSRPRLKGIDVGYYYKAGITDLINDDEDLDVFADYEPRSGKAIHGRYSLQVNTYIQGSDGTNSTLYNKYSAFRSDVVHPMFWGVNIIAATQEQIDILTKAYKVDSFRYAITVILIVVGGFLSLISGGLFVLDKIIDL
The following text describes a protein:
Function:
May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasmic granule. Membrane; Peripheral membrane protein. Note=Found on the surface of sperm tail. Stored in cytoplasmic granules during spermatogenesis.
Sequence:
MEKRGRGVKSSPIQTPNQTPQQAPVTPRKERRPSMFEKEAYTQILRERLRESIHNVQYVEPPFDDSIADIGKEWKSALAKLKFANSYRMEPLKKFQAHSVETKVQQILTESLKDVKYDDKVFSHLSLELADRILLAVKEFGYHRYKFIIKVLFIQKTGQAINIASRWIWDIAWDSWVAAKHEAESYVALVLVFALYYE
The following text describes a protein:
Function:
Involved in post-transcriptional regulation of gene expression.
Subcellular Localization:
Cytoplasm.
Sequence:
MRKAGANRNNERQGRNLGQQGPQMSPPGPSMMYPHHHQHQHHHQHQHQHQHQHQHPHQHPHQHHHHHPHHNGVYGNAYDNIRQPQMPPHSFGQGVSGSPWNSPPQQTPMYNQGYNQMSPGTGGGYGDMGGMYRDVHGGQYPSSPSHMGGGANIPYGRNPAMHNGLPAGAPLPGGYGALPHQGAHTPMGFGRGGQPLMEHMQPSGMYGAPMMRHDGYPDTRVSPPAQVGYGAGAPVGPPPPPPMPAGPPYGGVLPGAGVGPGGPMNASRPPAGIGGGGGGGGNAGYLEMRARGMGPQMPASNASRPPRIGTPDPGMMPPNRMNQSPMMGQGLPPQVGNFMPLPGVSPSPHAMIPTTPSMGDTFPGDDANMSGSTEALYDFLHDRGLVSVDNISKFFPEGYGKDDPALKVAVDGNFCLTSLRDELRKRDSLWFLHSTLPEELLMLVQQHVEWMRNMKLEPIWVFNGLSVSGDVETFLTTEAELRARDAVWSKLEDGEIPDEVEIQEAFDQPLGEDVQMAVARYLKEELGVMAVTAPFLNWAQMVAFHKEGIADLLMGPPEMLLLPYDEMKVIVQIDVSNSSVNYLDRDRVLRALFPNHVTETNTRVAGDRLMDLGLITATHAALSSARVTLNLSMQEVYEELSTPTPKFRSIKDFINAHACSQETGKKAGLSIKHSKGRGYLRYSAVFSTKSRDTPLVYLVRVLDPDLTNADMPTNLAGVLGHLVPLSLFYMQFSGLLSVRIMTAITQSYLRDECPVSDTKDYHTTLGLLMTMRSQVIGQILKRIAHPPPIKRTECLSWVRWFQPILAPMDRPRDLIDLDEWEISDSDQLKKLDEDCLADYSIASVLSVTADASRPAVEESNRPAGRVPIRYNSKRETFLAILLKSFDFLGYFSHSTAPNDAVDGMEMECCGMDGHDRGGSVPAAYHEKDLSSMKRSEASDINFMADEGLKDYPSVYFPIYLRATIKANPLDVQASFVLLTELVRVRIINSNPCRYINPANQQVEISMDDQDTNSDSRVLLASRIACLVKLPYRRASENLPFVWAPVYSRHLCAFTVMVRAMCRCLRELVEVITSTVFLSGNSSCSLQDFAEFASILPFGDVPSTIGGLLLHYVLVFPSDYQANLTSREERIEYLQGKFRDIPDLADHLHLVMSFTLQALYLINAYMLNDKETIVAKDQLTGTIVEDTIEMMWQKWRDHIDDNPPGDIHNLYPPRHQEPIPH
The following text describes a protein:
Function:
Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.
Sequence:
MLNNNIDERKILKKGYHISTKSTYFQVLYDVYLSKRDDWISVNSHIAPVGNNFQETLDLIKNQTKDSEVPLLFTNLAWERNCSITYIRNQVYFDENQEKKLYEHCRAIESSSIIRNSVGNSNILTDKYLLYKYLLNGEKYFAVPTILINKGRVDETKGKFFEGAEFTKNDGLWYLKDSMRNKSEGIYLFTNKEEAFEFSKRDENINRRFLLQKEITPMLIDYHFKFDVRVYIVSVFTPEYTKCYLFNEGIVRSTNSVYKRGDLHKESQLTNFCYQKQVSPEFQRIYRLSDITKDQLDIDPSEMFEKIKECTASCFGDVLTKLNQYKHHGFTLLGLDYIFDHEKKPYLLEINYSPSAFQDSPNNVPLVVQELCKQLPLIALDPILENKSPILNDFIEINSINHHCSKNGGNEDHNTEDFELF