lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the final stage of protein secretion.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Localizes at the cell tip and barrier septum.
Sequence:
MTLLELQKELFLSKINSVECATKWKVLIVDTKTADIINHFITIHSLLEEKIAAVEILENPRTPNSSFEALYILHSEEKLVDCILKDEEYDKRYPGIHIVFLDMVKEPLINKLRTSRIASKIRTVQVAYLDFTSLESRYFQVHDSFSGLRLYHPSNAAIIRQELSKVAHGIFSVCVSLGISPNIRCYYPKNAPHASKTMSFILANQLSEIVEEYCSKHPGYHEAASKSTCLIVDRSLDTAAPFLHEFTYQAMIHDLLPIKNEQYPYEILGPQGTEKRTGKLDDDDLVYTTIRHMHMRDAIEKLMKDFNQFCIDNTLFLDKERATSLNDMRSMLAGLSDFQELRDQYSLHLTMAQECMNIFEKQQLNLIGAIEQDLSTGSNVEGKVPRSVLSELLPLLDEGNAEESTKIRLLLLYIIYRDGIILQDLFRLFRHSNLSTSREQIFQNLEQLGTRVIKNLTDQSSKRKEVANSLPAGEDVYELSRYVPTLKVVLENLIQDKLDPELFPYVRNTTPQTEVSMEQTSLRSSRPSWTRSRSMASKLPREKMLVFVAGGTTFSELRTCYELSDKYNKDIYIGSTVCYSPNEWLDFFSKFQQPREALKFPEDKPRHIPCLEARPSPNRIQEQPNIDVPSTRYENTSSSDAVSIHKDEKKSKGKSHKLGKLMMSSKKDKDKSKEKVPTYGTSDKKKKKRFGVF
The following text describes a protein:
Function:
Utilization of purines as secondary nitrogen sources, when primary sources are limiting.
Sequence:
MSVENVERLSPEQADAFFGQSSVDLISRALGGQVLGCSDDFFASCENLINPADPIRKAGVFVETGAWYDGWETRRHNTAPCDWVIVKLGPSSGRVTGCEIDTTFFNGNHAPEVSVEAAFLPEGNPDAKTNWTPILPKLPCGPTQRHIYRFKEIPQQNFTHVRLCMYPDGGIARFRLYGNVVPVFPADLDARLDLAHMYLGGLVVQCSDQHFGKKDNLLLPGRGVNMGDGWETARSREKGHVDWVIVKLGARGYIDDALIDTNHFKGNYPKEVILEAIDSPDHIPGPDAQWVTILPARKLGPHMEHVFTNLQNNSTPMTHVRMIIIPDGGVKRLRIYGRRAAN
The following text describes a protein:
Function:
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for neuroblast specification (By similarity).
Subcellular Localization:
Cell membrane. Cytoplasm. Nucleus.
Sequence:
MDLGIPEFTCDVSLEDGKKPQPLQFSFTLYDLDGHGKITKDDIAGIVSTIYESIGKSVVVPHYGSKTINVRLTVSPDGKTKQTASAVKKAAITPRRRYRPRKLISDDDGSDTSENCPRVMRTRANTVVANTTINNNVKHKDNNVAKDEDVVDGLTKSSEAVETTFHNNLNGKGKTLNVKNDNIYESINNLKCCNIQAAQASKPTVALSQSPGTLNNSTATTVICRDCSLEGCTIDETLPLGTVVIPATTPAAAISSRAKRKVVRKSRSSRKASKLTDDFSRPRARSLSVGNENCYENMIGTTQEECWKSSLCRRELIEIIRDSMVKNSLCFQPNRKPLENSPKHRHRSHTIAARIGAEHCGETVMATQQALVAAHETNLCGYDSYLHQTICAAANANHAALHLNGGVVGNGGVFTALPLTTSTPNRLLQHHSHHAHAKAKRKEHRLAVATRSQVHHQVAQPVKLSTAVLNQQYPNLSAEQKLSRSINQVEKWLDNRSPKLVNKLKLAEEIAEKSPRVAAAKLKRSKSKEEITHKSTKFENVLTTDLLLDNLKITEDIAELSVVTPKKIFNKECLISSATKKNIRTHHTTKTVSTTTAVVPPAVDKASKNLIQLQYASVPINAELSECENLIRISDAEEELHQSVQQQQGTHQQQQQPQSSVSSPTHHHHHHAGASLLGENSGSSASAASTTAVHRYVHEHIHHHYHHFENDPDES
The following text describes a protein:
Function:
MYB-type transcription factor controlling the production of volatile organic compounds (VOCs), including floral volatile benzenoids and phenylpropanoids (FVBP), in flowers of fragrant cultivars (e.g. cv. Mitchell and cv. V26) by regulating the expression of ODO1, a key regulator of the shikimate pathway, and of several biosynthetic floral scent-related genes (e.g. IGS, EGS, BSMT1, BSMT2, PAL1, PAL2, EPSPS, DAHPS, CS, CM1, ADT1 and PPA-AT). Binds to and activates the promoters of at least ODO1, IGS1 and PAL1.
Subcellular Localization:
Nucleus.
Sequence:
MDKRTCNSQDVEVRKGPWTMEEDLILINYIANHGEGVWNSLARSAGLKRTGKSCRLRWLNYLRPDVRRGNITPEEQLLIMELHAKWGNRWSKIAKHLPGRTDNEIKNYWRTRIQKHIKQADQNMKKPSKCEQNDQKAISTSQASTGPTDTIDSYSPSSYTENTNNNMENITFQGNFPTETNENIWSMEDLWSLQLLNDATN
The following text describes a protein:
Function:
Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. DIS3 has both 3'-5' exonuclease and endonuclease activities.
Miscellaneous:
MISCELLANEOUS: The association of DIS3 with the RNA exosome complex appears to be weak explaining its absence in some complex purifications.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus. Note=Predominantly located in the nucleus. According to PubMed:12429849, found in the nucleolus. According to PubMed:20531386, excluded from nucleolus supporting the existence of a nucleolar RNA exosome complex devoid of DIS3.
Sequence:
MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK
The following text describes a protein:
Function:
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
Composed of a large N-terminal cytoplasmic domain (CD) followed by a juxtamembrane domain (JD) and a transmembrane domain (TMD).
Sequence:
MSEMSSFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTCDEYKGKLQVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDTSDPKAAGMGAQGRAGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNVPIDIEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASFMLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVSKPNRERQKLMREQNILKQIFGILKAPFREKGGEGPLVRLEELSDQKNAPYQHMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIRTELRPVKEMAQSHEYLSIEYSEEEVWLTWTDKNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISQQLGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDKKNKFANTMEFVEDYLNNVVSEAVPFANEEKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQGPPAMLQAYEDPGGKNVRRSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEPLDRSKFEENEDIVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFDSTTANMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSGKGEEVEAGATKDKKERPTDEEGFLHPPGEKSSENYQIVKGILERLNKMCGVGEQMRKKQQRLLKNMDAHKVMLDLLQIPYDKGDAKMMEILRYTHQFLQKFCAGNPGNQALLHKHLHLFLTPGLLEAETMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYLDFLHTVIKAEGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGVEDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYVDTEVEMKEIYTSNHIWTLFENFTLDMARVCSKREKRMADPTLEKYVLSVVLDTINAFFSSPFSENSTSLQTHQTIVVQLLQSTTRLLECPWLQQQHKGSVEACIRTLAMVAKGRAILLPLDLDAHISSMLSSGASCAAAAQRNASSYKATTRAFPRVTPTANQWDYKNIIEKLQDIITALEERLKPLVQAELSVLVDVLHWPELLFLEGSEAYQRCESGGFLSKLIQHTKDLMESEEKLCIKVLRTLQQMLLKKTKYGDRGNQLRKMLLQNYLQNRKSTSRGDLPDPIGTGLDPDWSAIAATQCRLDKEGATKLVCDLITSTKNEKIFQESIGLAIHLLDGGNTEIQKSFHNLMMSDKKSERFFKVLHDRMKRAQQETKSTVAVNMNDLGSQPHEDREPVDPTTKGRVASFSIPGSSSHYSLGPSLRRGHEVSERVQSSEMGTSVLIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQGPCHENQTCIVTHESNGIDIITALILNDISPLCKYRMDLVLQLKDNASKLLLALMESRHDSENAERILISLRPQELVDVIKKAYLQEEERENSEVSPREVGHNIYILALQLSRHNKQLQHLLKPVKRIQEEEAESISSMLSLNNKQLSQMLKSSVPAQEDEEDPLAYYENHTSQIEIVRQDRSMEQIVFPVPGICQFLTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGSISFNLAVFINIIIAFFYPYMEGASTGVLDSPLISLLFWILICFSIAALFTKRYSIRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPNNHSTASPLGMPHGAAAFVDTCSGDKMDCVSGVSVPEVLEEDRELDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLNSTMKLVSHLTAQLNELKEQMTEQRKRRQRLGFVDVQNCISR
The following text describes a protein:
Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSIGTGYDLSVTTFSPDGRVFQIEYAAKAVDNSGTVIGIKCKDGIVMGVEKLIASKMMLPGSNRRIHAVHRHSGMVERNCVYGEPIPVKELADRVASYVHLCTLYWWLRPFGCGVILGGYDRDGPQLYMVEPSGISYRYFGAAIGKGKQAAKTEIEKLKLSEMTCREGVIEVAKIIYKVHDEAKDKAFELEMSWICDESKRLHQKIPDDLLEEAKAAARIALEEMDAD
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MARSETDSVGGPVSLGSNGRLCGGNRARSDGWSFQQRNVFASLLILCAVCCFIECNDVITSKGELPAVSSVKNTVMAVFSPMVKAPGPCKFLAGTRKQNHQCRRDIGLPEAIKEARRLAVTHCQEQFRYDRWNCSIETRGKRNIFKKVYRETAFVHALTAAAITHAVARACAEGKMTKCQCASERKPEATSLAWRWGGCSDNLKHGKRVARNFLELQPKAGDPVAEMLRHDSEVGISAITSAMTDRCKCHGVSGSCSMKTCWRRLGDFNTTAALLRTKYHLAIRKIPINNKTTRRSAPGIFRPRETVYDQLYYFETSPTFCSVTRGRRCLHPDNCATLCCGRGYTTKVIKTLEKCRCRFTNGRCCQVVCDYCEKYEDRYYCK
The following text describes a protein:
Function:
This protein binds to 23S rRNA in the presence of protein L20.
Sequence:
MYAVIRTGGKQYKVSEGDFLKVEKLEGAVGDTVELKDVLMVGGETVAIGTPLVPSASVVGRIVDQGKDKKILVFKSKRRKNFRKMYGHRQPRTVLKIEKINA
The following text describes a protein:
Function:
May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 and RND3. Promotes RHOA activation mediated by GNA12 and GNA13.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSSPMSSLGRGKKPPLQGGRPGQRPVPFRHPEYTNDEESMFQEIFGDSPSSSISNSPKTRSPFASVGASPRHSPKGGKNTPGPGPTDHELMSTMMKRIAQLESRVTHYSKEVIEKDKKIKVLEEKTKLLTKAKDASKDSPSRVQELERKCLLLQQQVYEMETFLADYGMVWVGEETRSDSSVYVELGGELEEDGDGEQQEEEEAGPEERIDQATVGTNTMWKPAASYRTGTSVVSSDFQVDFNTLIENIKDLNVLAGEGEQKIVKTSEGATLQRADFIPLTLYANGIFLFNGPFRPMSEPSTQLFLQDIMDGYFPSELQTRFPDGVPFTVSDKRDTVFKDKRWKEEFPGSGHVLGGNTKPSRLLPSNLRGREEHSWGIDAGLRETSEAPVPMMSVDQFLNKVPSSVIKGGRVIDIRASLGETLKGGSGDRSSVTVIDTPVAKEMKERLEKSEAERPPSARDITTLRIKAGEQNFILKMRFSDTIGDVRRQLEHYRPAGSGDYELLTTFPNKVYRDNTASLHSCGLTPNAALHIRTRKT
The following text describes a protein:
Function:
In the cuticle, catalyzes the hydrolysis of beta-alanyl-dopamine releasing dopamine and beta-alanine; dopamine is a metabolite involved in the pigmentation and sclerotization of the insect cuticle. In the photoreceptor cells, catalyzes the hydrolysis of carcinine releasing histamine and beta-alanine contributing to the recycling of the neurotransmitter histamine in the optical nerve system. Also, regulates the cuticular hydrocarbon composition in females.
Subcellular Localization:
Cell projection, axon. Cytoplasm. Note=Localizes to the narrow axons and expanded terminals of R1-R6 in the lamina and of R7 and R8 in the medulla.
Sequence:
MSSGKILPRRQAVPVLYTRGTHYEVGFDMGRTFGSMIKNFLILSKPLNETYLPLYQSPKGRQIYNETLGSVKDSFPQYVRELEGVADGAEVEFHKLFLLHLDEILPQALKHQPRSKNQPTGCSTIIVNQKNCRLLGHTEDALTETLNHYYFVVAHIISDKPQGKYNVKEEHFMSLCYAGHLPGYTMSHNHHGLVFSINTISAELLRSGKTPRHFITRALLATSNVDDAFRVLKDAGVGAADACSINFTFLADPRQMCYNVEMAPSPDRKNESHLNIKEVPLGEHNYHVNQFDRIRQDQANDLMISSSISRMQTFGAYNPPMSEQDVRHMLGDVSGGVYCVWRENNSCDEVVKTIAVGIFDLSARTISLYSDNPSETEPHCRLPLLYK
The following text describes a protein:
Function:
Catalyzes the attachment of arginine to tRNA(Arg) in a two-step reaction: arginine is first activated by ATP to form Arg-AMP and then transferred to the acceptor end of tRNA(Arg).
Sequence:
MSTKLKLYLGRKVIDSLSKSTKFTPIELLPLIHVGNTTLNNTFELHLPLSTLEDHFGVPNVNEILKIRPDDIIKNIETKKDRANRKICFEIDRTIFIQDVIENSPNPDLNLKPRNIVVEFSSPNIAKPFHMGHLRSTIIGNFIGNLNSFLNNKVTKLNYLGDWGTQFGFIKVGVDELQHTQEAIKNNPLKLLYESYVHANKLAEKDPTVADRARQEFNKLEKGAPEGLEYWKEYMQYSQNELEATYKRLGVVFDEYNFESNYSAKDIQNVIDILSSKHIVQKEGDGKLSVDVNKRKVSIMKSDGSTLYLTRDIAAAIDRYNRYSFDKMLYIVDNSQSDHFNNLKAILHKMSLPWAHKLQHVKFGRIRGMSTRKGTAVFLRDILDECRELMIKKQVESPNTRVPIEDSAVSDILGVSCVIVNDLKQRRQKDYEFTWDSVLQVQGDTGVKLQYTHCRLYSLERNSGATRPKKVIPEVLKEPEATALVREIARFHEILNRSNEQLEACILVTYLFRLCNQINKALKVLPVKNTDPEIASQRLLLFITARQVLGKGMSILGLHPLDEM
The following text describes a protein:
Function:
Receptor for cAMP.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSSCSSLSMDDRVKIGYGSIAGASLSIIGSIGTIILIKIRNKKQEKKLLIQRKQQLSINNLNINSGSSSNIITISNSTTSLSSNNLNIQPPSFPSYSPLPTSISLSNNNNNNKNNNQKTKVSHFIINLSIANLLASIFMITIKLMMIHFNDKFIKVLPSTANHSFNALISVCTIGNGVIGFSFISTFFWTLAISMYIYQQFLSSSTINSNNNNNNINNINNNNNNNINNINNSKNNNSINNFNNSNKSNKIIKMLFYFVCWVIPFVLGSILVSGSRLIELNSDLPWCSIDSNIQLISFYFPLIICLLATTFFTILIKYKFSNDKLACSSSSLINLQSKIIQRLILFLIVILVCWVPSLISFFISFFSKNCKQFLWLEIISSTIQSCQGILNFLSYLSIFKKLKLYFKNLKKKFNNNNSNNSNNSNNNNSNNFNGGGIFYSKGKKVNNQNSNNFYFTFSTFDFDNNQIQEK
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.
Sequence:
MAESDAQKLQLMQELEIEMMADMYNRLTTACHKKCIPPVYNDAEIAKGEAVCIDRCVAKFLDIHERIGKKLGQLSMQDEQLLKK
The following text describes a protein:
Function:
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
Sequence:
MERHPITCHILDTTRGRPAENVLCQIYRIGNVSGGPQRATSETEALGKARTNKDGRVALWTLENSFPEFTTAPLPGLYKIRFETEQYFVTAANGDVEKTKSFFPFVDVHFTIPSPADAHYHIPLLISNYSYSTYRGS
The following text describes a protein:
Function:
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MTSPSASPPVASSKVNLQASHHLLSGALSGLSSAVVLQPLDLLKTRLQQSQEGIGSKRQKLRGVVKQVIKDDGISGLWRGTIPTLVRNVPGVAVYFYSLSAIRNRLSAVPYFSITVPVSGNKILTPSGQVKREAGSRSAIVKLSSGGNLLAGAVGRTSVGFVLSPITVIKARFESNRYSNYHSILGALSSLYRTQGVKGFYQGFTATAVRDAPYAGLYLVFYEKSKELAGRLPGVPNAALHSCSGIMAATLATIITSPADVIKTRMQVNPAEHPTLRKAIARVVQERGPLGFFSGTSLRISRKAVSAAIGWTVYEGLLIFLRDRKGQPQTGAL
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system.
Sequence:
MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETIYLESTGTMDKVREREKDNSGTTNIDDIDWDNL
The following text describes a protein:
Function:
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MVPMTTLAPLGSGSDPDSFLRLGIPSKGRLSELATGLLNQAGLSFRRQNRGLFARVSGLPIDLIFLRTDDIPTLCAEGAIDMGITGSDLIEEAGANVEQRMAFGVGRCRLAFCVPDDEDYTDAAQLNGKRIATSFPHVTEQYLATKNAKAHLVSLSGSVEAMIRLGVADAIVDLVETGSTLAANRLRILEEIGHYETVLIQNGTHRCKEVADRLVSRLEGVVLARDYSLVEYNIPRSRVSEAEKITPGFNSPTINSLEDKDWCAVQVMVRRGEVVEVMERLKEIGASGIFEMTINNCRL
The following text describes a protein:
Function:
Is required for the expression of the adjacently encoded xylanase Xyn11E in an active form. LppX seems to act as a specific chaperone necessary for the correct folding of the xylanase during secretion across the cytoplasmic membrane.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MRKWLIFLLIAAVAGLSACSTSGNTTVSDDLVLVEGGAFKTSKSSYSDKNVTLSDFYIGKYEVTQKQWMDVMGDNPSGFKGEERPVERVTWYDAIEYCNARSIKENLKPYYTIDKETTDPDNKNENDNIKWTVTINEGANGYRLPTGAEWEYAASGGQKSQNFTYSGSNNPDEVAWYWMNAGEKPLTGDWNWPAIENNRNQTKPVGQQKANELGIYDMSGNVREWCWEWHSHPETPENTWRISKGGGWVSSVNTAEISYPGKFDANGLGPDQGLRVVRSK
The following text describes a protein:
Function:
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
Miscellaneous:
MISCELLANEOUS: Part of a cryptic operon that encodes proteins involved in type II secretion machinery in other organisms, but is not expressed in strain K12.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQRNAIERMRNETLALWIADNQLQSQDSFGEENTSSSGKELINGEEWNWRSDIHSSKDGTLLERTITVTLPSGQTTSLTRYQSIDNKSGQAQDD
The following text describes a protein:
Function:
Probably involved in the defense reaction of plants against pathogens.
Sequence:
MSLPYIISAAFSFLLLLHLAVAGVQPQSPPTSTSKNSMPATTASPRRRSYIREFLQAHNKFRSAFHIQPLTWDRNLTRFARRWGEQRAADCRMIHSYGPYGENMFWGKLEHWTPTEVVNSWAGEDKHYNLDTNECADGQTCGHYTQIIWKESLRLGCVRVNCDNGGLLVICEYDPPGNYVNEKPI
The following text describes a protein:
Function:
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Subcellular Localization:
Nucleus.
Sequence:
MEGVLAVSDGHDLYTNDVGSVRGNLEPKIISFVKNFSKHKNNIFDYREQLQRNIRMGKYFLEIDIMDLQNFDESLKEALFKHASEFISIFENVLSVQVLSMRGWEKKEDYIESDTGGPMMQVIIKDTQSKMIQPRMLQSSFLSKVIRVSGIIVSISRVEPKVTKAILRCRSCQKEIAVIVPSCCGIINYPKSCDGVSPVTGKKCPPDPYDVVTEKCKFVDRIVLKLQETPENVAPGEVPRTVTVILERYLVVGLTAGQRICIEGIFGASLQRKGTISTSYIRAIGIEISGQVVSQDDRRMKEVARTITKEKLIKSIAPAICGYDDIKEAVLCLMLGGSGKALPDGTHLRGDINVLLMGDPGTAKSQLLKFVQMATPIGVYTSGKGSSAAGLTAAVNKDSSTGEFYLEGGALVLGDGGVVCIDEFDKMNEVDRVAIHEAMEQQTISIAKAGITAVLNARSAVLAAANPSFGRFNERASFGDNVNLKTTILSRFDMIFMIRDKHDAKRDKEIVKHIMDIHRQDVKVDNLSTDILKEYIAYCKAYCIPRLTENASNKLSNYFVSIRQKVRENKLENDNDEGIPITVRQLEAIIRISEALAKMTMSDIADENHVDEAIRLFELSTMNSAVRQKEKHKKRRDDK
The following text describes a protein:
Function:
Controls the pigmentation pattern of the adult cuticle and larval mouth parts.
Subcellular Localization:
Secreted.
Sequence:
MMEVRGTPVALAFTVSCCMLLALLPVHIVANDNLRVAYQWKEIDFEFPSETERQEAIASKSYIAENVIPVGLEVYKKRLFLTLPRWKEGIPASLAYININETTTQSPRLHPYPSWSAHRRTSETEAPEIVSPFRIRADRCGRLWVLDTGVEELLGNTTVTSPTSLLVYDLHNDNLLRRYKFPADHLKENSFYANIAVEDNDCDDTYAYAADLGSPGLVVYSWKQQESWRVKHHYFHPDPLAGNYNITGINFQWDDGLFGIALKPQSDGYSTLYFHPLSSLNEFSVSTKVLRNQTYATESGNYHEFKILGSRGPNGQAGVAFVDQKTGVIFYALPNLNAITCWKTSNRAYTIKSLGRVYMSTVDMVFPNDVKVDDESNLWVLSDRLHQYMYESLNRNDVNFRVLTATVKDAIQNTACDTNIKPLPDIITNLGDILRPSTSTIAPKAGSSSAWPSPSHTNAIVVLSMLITMLRVSYCIRI
The following text describes a protein:
Function:
Component of the pid-1 variant of the PETISCO complex which is required for the biogenesis of a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs). Within the complex acts as an adapter which binds to the complex via erh-2. Involved in the biogenesis of 21U-RNAs which guide the piwi protein prg-1 to its DNA targets for silencing. Plays a role in small RNA-directed transgenerational epigenetic inheritance.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=Expressed predominantly in the cytoplasm. A small fraction is nuclear or located near the nucleus. Dispersedly distributes throughout the cytoplasm in early embryos. Localizes to puncta in the perinuclear region in the germline syncytium.
Sequence:
MSAKREFSHITLASTPFKKRIDQNSLKTDSDIEKDTNIAHKCAERFNYNTNLHRKVTLSDRFELAALGYEMKAKPRTIIEKHNDCDEFHFIYRKEKKNDYGTGSPLSAGLSLSNPLPAGRGFLSPAIQNTSNQFTFSGSPRITPQKHTPVSANHKPARSIFDDIPSNIA
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Sequence:
MSLLNKPKSEMTPEELQKREEEEFNTGPLSVXTQSXKTXTQVLINCRNTK
The following text describes a protein:
Function:
Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MAFRCTLRRLECYRASRLMPYKPSFLFSLISNVNEYERFVPFCQKSKVTEYDPKTGYPTKADLTVGFKGLCETFDSKVVCDPVALTVLADASHHRLFRRLKTHWSIEEASRGRVRVDLEVDFEFASKLHGMMSKFVGSSVASEIIQGFVQQAKIKHKLESENEK
The following text describes a protein:
Function:
Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MRNLVNREQTKAKVLVVYAHPDPQHSVANQVMMEKIADLEHVSIIDLYATYPNFFIDVHAEQQRLREHDVLVLQHPLYMYSCPALLKEWIDRVLSKGFAFGKQSELKGKLWRSVITTGGNHTAYDQRGYNRYPLNEILQPFELSAALCQMHWIEPLVLYWSRNISDQERAQHAERYRQWLQEIAHWQGEPYDATDQ