lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA; Ribosome biogenesis factor; required for recruitment of Myc to nucleoli. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in neuronal-lineage cell proliferation.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQLDENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHKWFWLLPVKQSGVPLAKGTLITHCYKDLGFMDFICSLVTKSVKVFAESPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISVKVTMEDTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQQPESLGKKPFPHLCSVPDLITILHGISETYDVSPLLRYMLPHLVVSIIHHVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKEIADLKKQELFHRFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRLLAINHLKKIMKTSKEGVDESFIKEAVLARLDDDNIDVVLSAVSAFEIFKEHFTAEVTISNLLNLFQRAELSKNREWYKVLKIATDILIKEEILSENDRLSNQVVVCLLPFMVINNDDMESAEMKIAIYLSKSGICSLHPLLRGWEEALENVIKSTKPGKLTGVANQKMIELLADNINLGDPSLMLKMVEDLISLGEEESVNQKQKVTFHVVMSVLVSCCSSLKETHFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPAELWAHYVEELNSTQRMAVEDSVFLVFSLKNFIYALKAPKSFPKGDIWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFSSVLWTYGSSLSNPLNCNVKTVLQTQALYVGSAVLSSQKTQCKHQLASISSPVVTSLLVNLGSSIKEVRRAAIQCLQALSGVASPFHLIIDHLIPKAEEITSDAAYVIQDLATLFEELQREKKLKSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVHGEMVLSQLLPMAEQLLEKIQKEPTAVLKDEAIVLHLALGKYNEFSASLLNKDPKSLDIFIKAVHATKELYAGMPTIQITALEKITKPFFAAISDEKVQQKLLRMLFDLLVNCKNSHCAQTVSSVFKGISVNAEQVRIELEPPDKAKPLGTVQQKRRQKMQQKKSQDLESVQEVGGSYWQRVTLILELLQHKKKLKSPQILVPALFNLLSRCLEPLPQEQGNMEYTKQLILSCLLNICQKLSPDGGKIPKDVLDEEKFNVELIVQCVRLSEMPQTHHHALLLLGTVAGIFPDKVLHNIMSIFTFMGANVMRLDDTYSFQVINKTVKMVIPALIQSDSGDSIEVSRNVEEIVVKIISVFVDALPHVPEHRRLPILVQLVDTLGAEKFLWVLLILLFEQYVTKTVLAAAYGEKDAILEADTEFWFSVCCEFSVQHQIQSLMNILQYLLKLPEEKEETISKAVSNKSESQEEMLQIFNVETHTSKQLRHFKFLSVSFMSQLLSSNNFLKKVVESGGPEILKGLEERLLETVLGYINAVAQSMERNADKLTVKFWRALLSKAYDLLDKVNALLPTETFIPVIRGLVGNRLPSVRRKALDLLNNKLQQNISWKKTIVTRFLKLVPDLLAIVQRKKKEGEEEQAINRQTALYTLKLLCKNFGAENPDPFVPVLSTAVKLIAPERKEEKNVLGSALLCVAEVTSTLQALAVPQLPSLMPSLLTTMKNTSELVSSEVYLLSALATLQKVVETLPHFISPYLEGILSQVIHLEKITSEVGSASSQANIRLTSLKKTLATTLAPRVLLPAIRKTYKQVEKNWKNHMGPFMSILQEHIGVMKKEEVTSHQSQLTAFFLEALDFRAQHSENDLEEVGRTENCIIDCLVAMVVKLSEVTFRPLFFKLFDWAKTEDAPKDRLLTFYNLADCIAEKLKGLFTLFAGHLVKPFADTLNQVNISKTDEAFFDSENDPEKCCLLLQFILNCLYKIFLFDTQHFISKERAEALMMPLVDQLENRLGGEEKFQERVTKQLIPCIAQFSVAMADDSLWKPLNYQILLKTRDASPKVRFAALITVLALAEKLKENYIVLLPESIPFLAELMEDECEEVEHQCQKTIQQLETVLGEPLQSYF
The following text describes a protein:
Function:
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular Localization:
Cellular thylakoid membrane; Single-pass membrane protein.
Sequence:
MATQNPNQPVTYPIFTVRWLAVHTLAVPSVFFVGAIAAMQFIQR
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MTRTWLSTSQSKEKKCVDTFQNMIDSNVAESLRQVTKSIDEVLGMIQVQQQHHLHRHNNVTAAPGSDPDPYDPALSRTADVTLSQNETQVSHAYGPSLDAIAAAPSHSQKQFVIFVKKGVYKEYAKIDKTKTNLVLIGEGLSVTTISGDRSNASGWATMKSATFAPLDKCSFACIQKLFGEDHGTCAKLHASEDDENSTNMVITYYVRAQGFIAMDIGFENTAGPNTTSPTRLHPDPQSMFKITSSNFFIFIFFHGYKFGQRFSLVVKNSTQLPNTRFPSSKSHAMTAITWATRRRKKL
The following text describes a protein:
Function:
Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MLRHPRVWMGFLLLSAISQANAAWTVNMAPGATEVSRSVFDLHMTIFWICVVIGVLVFGAMFWSMIVHRRSTGQQPAHFHESTTVEILWTVVPFVILVVMAVPATRTLIHIYDTSEPELDVQVTGYQWKWQYKYLGQDVEYFSNLATPQDQIHNRQAKDEHYLLEVDEPLVLPVGTKVRFLITSSDVIHSWWVPAFAVKRDAIPGFVNEAWTKVDEPGIYRGQCAELCGKDHGFMPIVVDVKPKAEFDQWLAKRKEEAAKVKELTSKEWTKEELVARGDKVYHTICAACHQAEGQGMPPMFPALKGSKIVTGPKEHHLEVVFNGVPGTAMAAFGKQLNEVDLAAVITYERNAWGNDDGDMVTPKDVVAYKQKQQ
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MPVGAVPAITGKLRKRLILDLTVALGGGTALGYGYWYAIHVPSVSRRDAFYAKLQAERTE
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli partially inhibits cell growth after one cell generation. Its cognate antitoxin is MazE2. Probably an endoribonuclease (By similarity).
Sequence:
MRRGELWFAATPGGDRPVLVLTRDPVADRIGAVVVVALTRTRRGLVSELELTAVENRVPSDCVVNFDNIHTLPRTAFRRRITRLSPARLHEACQTLRASTGC
The following text describes a protein:
Function:
An ATP-dependent DNA helicase which unwinds DNA in a 3'-5' direction.
Miscellaneous:
MISCELLANEOUS: Cyanobacteria do not encode always the HRDC found in most bacterial RecQ proteins.
Sequence:
MADRQSLEEALRRIWGYDHFRYPQGEVIDCLLARRDCLVVLPTGGGKSICFQLPALLGEGLTLVVSPLVALMEDQVQSLRRQNLPAACLHSQLSRPERKQVLYQLGQQQLKLLYLSPETLLSEPVWNLLRQPQVKLQGIMLDEAHCLVQWGDSFRPAYRRLGALRRGLGRDKGQIPLAAFTATADRQQQNLIVEGLNLRSPECFQVSPHRPQLHLKVKMVLSEYCRRQQLRRFLLKHLQESGLIYVRTRTMAINLAQWLQERGFDSEAYHGGLGPHQRRQLEQKWLTGQISSVVCTNAFGLGIDKPDTRWVLHYQAPLMLMDYLQEVGRAGRDLQPAECLTLVSEPTGWLDSGDRQLRQYFLSQASKYLQRAEVLSQQIPSQGNLGQLKAHFPDLEMALAWLHRRGNLEWLDPFNYRINPGHYQANPLEELKSQYRLMTQYLTTSRCRWQTILVAFGDNSPAARRPCGTCDNCLVGRC
The following text describes a protein:
Function:
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
Subcellular Localization:
Nucleus.
Sequence:
KQKLKVGKSKVLPSNFTDTSYRTKALVLPTQNALATETLSVDEKTKAQFAHSLGLLKHHNSNQRKDALEKIAANLEENPDLLKVSISMIVRVTAPLILDESPQVRNLLLTFFKNQILSVEPTLLQPNINNLFLFTHSAMTHISPPIRSDSTKFFDLLLDVCTTKLDDSVLSLHWNKSLDCFGNLLGWNKDTVSTHGSVRLSKSSSNSMVRHIKTCRKLFEIGLRKDSHKEEGSMCYKFSFPYFNCLTVVHPMFNKLYTPCTFSHLSLFSTTRHELVDSPEYRWDSIVPFLPGILSFIRDSWSDYCPLVAEVRNTQEQSITCDNILVIFTLIYQFYQRSEHQKSALTKKFAKVLQKIRHDAELLKLNFGYDKKWGVVLNKIDKFDDEEAT
The following text describes a protein:
Function:
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGKKDEKSQQGEELVKVNKWDGSAVKHALDDAVKTCLLGDRPQLKEQFGLVNTRLALCALAVSVAIMAHAWDFTHPFPESRPVLLFSVLAYFALLGILTLHSSFREKGTFAVALQKDKERERLWEASSDMRKYDDKYLLTLSVRDTKNGKRREQSSNKSCAAFIDQNGIVLDNLVANEVNRLFNALAADKKNASSLSSN
The following text describes a protein:
Function:
Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism.
Sequence:
MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE
The following text describes a protein:
Function:
Receptor kinase acting as an early component in abscisic acid (ABA) signaling. Required for darkness, ABA, high CO(2) and hydrogen peroxide (H(2)O(2)) induction of S-type anion currents in guard cells leading to stomatal closure, possibly via the phosphorylation and activation of the anion channel SLAC1 and as a scaffolding component. Seems to act in parallel with SRK2E/OST1 in the ABA signaling pathway which regulates stomatal movement. Binds ATP. Involved in the local and/or systemic stomatal responses (e.g. stomatal closure) to light stress.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MNLSRILLLSMFFLSAMGQLPSQDIMALLEFKKGIKHDPTGFVLNSWNDESIDFNGCPSSWNGIVCNGGNVAGVVLDNLGLTADADFSLFSNLTKLVKLSMSNNSLSGVLPNDLGSFKSLQFLDLSDNLFSSSLPKEIGRSVSLRNLSLSGNNFSGEIPESMGGLISLQSLDMSSNSLSGPLPKSLTRLNDLLYLNLSSNGFTGKMPRGFELISSLEVLDLHGNSIDGNLDGEFFLLTNASYVDISGNRLVTTSGKLLPGVSESIKHLNLSHNQLEGSLTSGFQLFQNLKVLDLSYNMLSGELPGFNYVYDLEVLKLSNNRFSGSLPNNLLKGDSLLLTTLDLSGNNLSGPVSSIMSTTLHTLDLSSNSLTGELPLLTGGCVLLDLSNNQFEGNLTRWSKWENIEYLDLSQNHFTGSFPDATPQLLRANHLNLSYNKLTGSLPERIPTHYPKLRVLDISSNSLEGPIPGALLSMPTLEEIHLQNNGMTGNIGPLPSSGSRIRLLDLSHNRFDGDLPGVFGSLTNLQVLNLAANNLSGSLPSSMNDIVSLSSLDVSQNHFTGPLPSNLSSNIMAFNVSYNDLSGTVPENLKNFPPPSFYPGNSKLVLPAGSPGSSASEASKNKSTNKLVKVVIIVSCAVALIILILVAILLFCICKSRRREERSITGKETNRRAQTIPSGSGGGMVVSAEDLVASRKGSSSEILSPDEKLAVATGFSPSKTSNLSWSPGSGDSFPADQQLARLDVRSPDRLVGELHFLDDSIKLTPEELSRAPAEVLGRSSHGTSYRATLDNGVFLTVKWLREGVAKQRKEFAKEVKKFSNIRHPNVVTLRGYYWGPTQHEKLILSDYISPGSLASFLYDRPGRKGPPLAWTQRLKIAVDVARGLNYLHFDRAVPHGNLKATNILLDGAELNARVADYCLHRLMTQAGTVEQILDAGILGYRAPELAASRKPLPSFKSDVYAFGVILLEILTGRCAGDVITGEQEGVDLTDWVRLRVAEGRGAECFDSVLTQEMGSDPVTEKGMKEVLGIALRCIRSVSERPGIKTIYEDLSSI
The following text describes a protein:
Function:
Positively regulates organization of the outer plexiform layer and Muller glia cells in the retina. May protect actin filaments from depolymerization (By similarity). May play a role in development of normal skeletal muscle morphology and muscle fiber type composition (By similarity).
Subcellular Localization:
Cell junction, adherens junction. Cell junction, desmosome. Note=Colocalizes with actin stress fibers.
Domain:
Xin repeats bind F-actin.
Sequence:
MAEVAKQKKATEAVCGDEDFPPPPPPLPRPQVLESLQKDLSQNFLPVPPPKETFSEIYQQRQKSELKRLFKHIHPELKMTVDDVVDDELIDAINPQAADAAYQGEVQSMRWIFENWTLDNIGDPHETKKLLCEENPQGGDVKGKSSLFEHSTFDSQHAAGAERAGVVRGDVRTATWLFETQPLDSISKSKIEDEEIVEVVLKEPVQKGDVTGARRLFETKPLDSLGRCCSVEDQHFLTLKSELQENKGDVKKTVKLFQADPCCALRDSNGKIHEIKSICREEIMSSDFKTARWLFETQPLDHINEGAHVQIIRGISLEEAQRGGVDKKKWMFETQPLDAIHEGVVEEQKFQGTAVEGFSGAADVHNKLQLFENQPLSSLKGDSEGDVLEKEAIVGGNVGSTLWLFETQPMDTLKDSYEVGRLQKVMVSSDEKGEVQDKRMQFEKSTAGKTAGDSGNKVQNDEKGDVKTFKSLFETLPLNVSEKAQSQIHDITSGDVKGHCSLFETTPLYAIKDCAGKFHEVTTVSREECIKGNVQNYKWMFETRPLDQFEEGSGKVELIKGITRQEDMTDDTRTAKWMFETQPLDCMSLNSRTDVDSTQKEFKKSNVKTCKWLFETKPMDMLYEKSEGKQDVEPVPKADVKSHTWLFETQPLDNIKDKENLGLKLCSTVQEDVKSDVNVKTVKHLFETEPLDRITDQADSGQNVRCVSQVDMQSGDVSRVKEIFESKSLGTESSKWSEEQKNEIQSGSVHKFTWLFENQPIGDINEKEERIVSCDVEAGDVGGKKFIFETLSLDKIKDKDELLEHPSMIIEKPLSSSVNVKSNTMLFESQPLYAIRDKDGQFHEVTTVMKEEVMRGDVRGARWMFETKPLDTIQADKEIYVIRAVTQEDVHKGDVKSARWKFETQPLDSFTPHEGPSVRVVEDIGNEKCVQQSRQLFETEQASQKKFVRMVSVTDVQQGDVRTSTWLFENQPIDTLKGEPDEQNNLTAVHREDNTKGDVKRCTWLFESQSLDKIKDNKPTEELVSSREEIPKADVKSTTWLFETTPLDKITVESVTDILYRLCHNSFIHSSGIIIQANDYKYVNMAKYQIMKDEGPKVLKEEVVEGNIRNLMLQLLFKPNIKPMVVLLKEDEQGKMHSTVLEIPFQQPGSATNPEAECKTQEAVKIIENLLVQQKEIKTGLVMQESEGGQPEMTVYSLHCESSLTESQTITRGDVKSTIGNLLATVHSQQTKQSCRMEEIERGNVNLYKSCIEKGDLKSLQRELSEEDLVTSCRDQIEIVQGDVKEAMRHLSQQREQVERTILDVVPGDVKNVKKVFSDVCTDLSIGNCVPREEIVRGDILSAKQQLGEAVKQQVMVQKEEIVSGDIKATLESLERAKQQSMQVEREVIKPGTIYDLNVEAEEMCSEENESKLVKEEIIPGDIKAAKRSLERAKNQSMKVEREPITPGKLYNLNETSQCQSSTTVEQSTTSTYSNHRITTTFRKVSDIEKDQESIKRLCCLNEVGGGGKNIYINTEDALRMVDISESVPDVVKGDVKATIQSLRSASTEQRSVDREEIVRGNMQETLQCLKKSSINISRGDYKAAMLYKQSGQPYTQSKITNDSGTKDCKQSFDHIPSSHTQLSSSVSVTRSEHPTSLALNSESVSSNADNSKNSSAFTGKDEHPPPILPKTGHQVKDQKPVIPPKPLHITTSSPPLFTETSNMCPNSTVSINDTQQTPAIPLKVTPSNKMFTHETEIAKTSNKIKDKESKIHEQVQRTNLTDPTDFQRMQYTEQWVQNSHMQITDTPSVNKTDSFKNGSFPGDSIGMEKNVVQRINAAEEIRMCYSKDNDELNKGFKAVLQNFGEKKTTTDTGSPFPKKIKVVQKENIQEQAKTSNKDELHFTSRDTSSTPNKHEVPSIHNNSENKVVLREKKAKRETEDERRQRLSIHRDEIMRGNVKAAMEIFENLMRREELKVILSKVQEIEGETFEVDVRSLKTLFENVPAWITNPKENTKRRHRPRVAKETEGLRDDLESISSVEAAFEDLEKASMDIVNLKEQTLAKLLDIEEAIKKALYSVSNLKSEADIAGLSGLFSESLSPDNVSPSTKNIRKISIVSSKTKPAQSNQMQSADNRALYKEVPHVPQVQVSKQSSNVPSSPSFISIHSAARKPAESPTDKPKTNADQSNAGSSSSQNSSASHICSPPSPRRKVSVLEVQRVPEVPSGIFGTKTVSEKYEETDCFGNTYYSSKRSTFVTRQSETELSSSYDVVTSPRRSEGMTSPVLQRSGQSFSSNSLSKGKDRKVFVTFGHPNTEKH
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42 (RPL42A and RPL42B) at 'Lys-55'.
Miscellaneous:
MISCELLANEOUS: Present with 4010 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MDDFSRDTENFVCWLKTTAEIEVSPKIEIKDLCCDNQGRAVVATQKIKKDETLFKIPRSSVLSVTTSQLIKDYPSLKDKFLNETGSWEGLIICILYEMEVLQERSRWAPYFKVWNKPSDMNALIFWDDNELQLLKPSLVLERIGKKEAKEMHERIIKSIKQIGGEFSRVATSFEFDNFAYIASIILSYSFDLEMQDSSVNENEEEETSEEELENERYLKSMIPLADMLNADTSKCNANLTYDSNCLKMVALRDIEKNEQVYNIYGEHPNSELLRRYGYVEWDGSKYDFGEVLLENIVEALKETFETNTEFLDRCIDILRNNANIQEFLEGEEIVLDSYDCYNNGELLPQLILLVQILTILCQIPGLCKLDIKAMERQVERIVKKCLQLIEGARATTNCSATWKRCIMKRLADYPIKKCVSIEKPSKGNSLTREELRDVMARRVLKSEIDSLQVCEETIDKNYKVIPDEKLLTNILKRKLTEEEKSSVKRPCVKK
The following text describes a protein:
Function:
Involved in the regulation of nitrogen fixation activity by the reversible ADP-ribosylation of one subunit of the homodimeric dinitrogenase reductase component of the nitrogenase enzyme complex. The ADP-ribosyltransferase (DraT) transfers the ADP-ribose group from NAD to dinitrogenase reductase. The ADP-ribose group is removed through the action of the ADP-ribosylglycohydrolase (DraG, this entry).
Subcellular Localization:
Cytoplasm.
Sequence:
MTGPSVHDRALGAFLGLAVGDALGATVEFMTKGEIAQQYGIHRKMTGGGWLRLKPGQITDDTEMSLALGRSLAAKGTLDVADICEEFALWLKSRPVDVGNTCRRGIRRYMHEGTTTAPYSEGDAGNGAAMRCLPAALATLGHPADLEPWVLAQARITHNHPLSDAACLTLGRMVHHLIGGRGMKACREEANRLVHQHRDFHFEPYKGQSSAYIVDTMQTVLHYYFVTDTFKSCLIQTVNQGGDADTTGALAGMLAGATYGVDDIPSGWLSKLDMKVEREIRRQVDALLALAGLD
The following text describes a protein:
Function:
Could be involved in nucleoside transport.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKTTAKLSFMMFVEWFIWGAWFVPLWLWLSKSGFSAGEIGWSYACTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGALLMYFAAQQTTFAGFFPLLLAYSLTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQILGYADISPTNIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILLRDKNFLVFFFCSFLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLLLGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGVSYDFYYVTAYIYVDKKAPVHMRTAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVNGLTFNWSGMWTFGAVMIAIIAVLFMIFFRESDNEITAIKVDDRDIALTQGEVK
The following text describes a protein:
Function:
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSDKPDMAEIQKFDKSKLKKTETQEKNPLPSKETIEQEKQAGESYWSGLPFPSPAHFPDEETDTNRIKGLVQGHTISKYLRPDLNSGR
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.
Sequence:
MDGLTPAEQREFQSRMERKQMKEFMGMFSNLVTHCFDACVDDFTTKSLIARESGCVSRCVQKFMAGSERIGQRFQEQQAQMMSQPPPGSR
The following text describes a protein:
Function:
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
Subcellular Localization:
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Sequence:
MDLNTILIIVGIVALVALIVHGLWSNRREKSKYFDKANKFDRTSLTSRSHTQEEMVQPNNISPNTYVENGHTPIPQPTTEKLPSEAELIDYRQSDKSVDDIKISIPNTQPIYDMGNHRSEPIQPTQPQYDMPTANNVASMTLEQLEAQSQNVGFNGINSSSPELRVQLAELSHEEHQVDYNLSFNEPKAETTAHPKQTTGYIQLYLIPKSSEEFNGAKLVQALENLGFILGKDEMYHRHLDLSVASPVLFSVANLEQPGTFNAYNLAEFNTIGIVLFMQLPSPGNNLANLRMMMRAAHTLAEDLQGVILTEEQEIFDANAEQAYLARV
The following text describes a protein:
Function:
Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds directly to 26S ribosomal RNA.
Sequence:
MPPKFDPTEIKVVFLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHNGNISMDEVISIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAVSKPLSHWLLVDLVAALLQSCLWVATCMAAPSFLFFLSTELNLPWEPMGFLNKERLTVSCLVVFHWFRPFIWLWVCSSGAGGGVDWL
The following text describes a protein:
Function:
Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.
Subcellular Localization:
Chromosome. Note=Specifically localizes to unsynapsed chromosomal regions during meiosis.
Sequence:
MNFNVWNIKEMLSIPSGSGNKKSSNWNNNQNDYSSLSDSQFLFGSQFCPENSETLSAPLDFGAHLRHSKQSQQNYLEGEPSIFTKYQTKPQLFGGDIKDGGLFPPPLSVGKSKGLLEQFEEKKKRAKDKCDSETLYNFVSNVRESILRLQTSVEKSEDHLSSRSQSILDSLETVAKTLQETIQAQNDLVFEAVQDKGNMEQAILEMKKRFEARQGEFIEMKSNLKHLEVLVAQQSQEFQQLCEQLGQLNVPSVLAELKRLISVPPVKDSASQTSPPLAQSLNLTRQEKYTSEKPVLWQAQALPAAWNPGMGSLQPGEFDVWGEGAKNDDLQEEAALPAFGSHERNRHVKDKVVQTNCKNWAVTKTGAKNHGSSVPGHKIPSDRDLVSQGASQLTSLEINFSTSIKNACQKYQAQSMFLCDPREHLVIKQKDGTVEMRGKDKKQQPRKAHRAHRGRLIASKQKQIPIQTCKFNSKYQSPQPAISVPQSPFLGQQEPRAQPLHLQCPRSPRKPVCPILGGTVMPNKTVRAVQGRLLQLSRCSSQDNWLLSSSSQGDHQMSWFSDLNLGCSETPLCKEAGKNLLYDLGFDSSDDDGF
The following text describes a protein:
Function:
Required both for centrosome duplication and maturation. Required for pericentriolar material (PCM) recruitment.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the centriole throughout the cell cycle and accumulates on the PCM during mitosis. Requires spd-5 for its accumulation on the PCM. Recruitment to the centrosome during prophase of the 1-cell embryo is regulated by the cye-1/cdk-2 complex.
Sequence:
MEDDAPMNLCNEQFEEIEDSPIDDNDNESFYNADGDVELEEEEVHETPKNFKNGGRFKTNMTNPKVNDLTTIEEKNEDLRSAASSRSASRPASVMSDKSFSSQFEFQSGGENAIEEYTNQVFADENKADLLFPETSKFMNGASPPKDKHHSWEPSIHHYDKQPPPDIQTNSPVFGNLNHRKNKLIPQARAKPGANDNEIVERDNDENVPTTSDKSAFITSPMNSTNHDEKTSTPKRPTNRKIGQYQGPNFDLSSIYVGSPQHQNTSISTGQQMPTSSYSHAHSETMMTNQTINESMVRRVLNGNNKNQDLFAALEEARKRRAAQPSKPDFRINTTRTRVPIKPTSARHSGNVVSSTSNDNTTAASSKDLTTSRKAMETFRQNASMADATNSNTASMTSILSTISTARTDISRSSRNHGGGFSNTSVSTVIPANNGNVSLSHGRDGRDSVSSVRTMSRASSTSTVYAGSTFSGVSKPLRIHAKRVAFGCVAVGETLRVEVEVENISDRQCLVRASTDSTTPVYQILDNKLTMVDPKKSIKFQVSFSPSSVGRYQVIMSIEVPAQNFIHKIPMWGNGGIAKFVPTSPDLQQTINQSEYAMCTSCAKRISFKISNSAGTRDGFAMIKVFDSAMRQLPDGCVAFFPAPGFIVKKKSDKRVDIRIDSSYIDLHDENNFRTSSSLSTASTTSSFQRRILPGAKFFVHVVWGEETMRTRLRLLEVRTGQHQLIDGHDFTSFQFSDEEVLRAVPVGFPAIKPEDRDLFAASYRSFFINFFTSTTEFRAATSRKKKEICSNDDSTLLETTAFRNQTFVNDVTIVPNTRFSNRK
The following text describes a protein:
Function:
Involved in cell wall beta(1->6) glucan synthesis.
Sequence:
MRQFQIILISLVVSIIRCVVADVDITSPKSGETFSGSSGSASIKITWDDSDDSDSPKSLDNAKGYTISLCTGPTSDGDIQCLDPLVKNEAISGKSKTVSIAQNSVPNGYYYFQIYVTFTNGGTTIHYSPRFKLTGMSGPTATLDVTETGSVPADQASGFDTATTADSKSFTVPYTLQTGKTRYAPMQMQPGTKVTATTWSMKFPTSAVTYYSTKAGTPNVASTITPGWSYTAESAVNYASVAPYPTYWYPASERVSKATISAATKRRRWLD
The following text describes a protein:
Function:
Component of 1,2-phenylacetyl-CoA epoxidase multicomponent enzyme system which catalyzes the reduction of phenylacetyl-CoA (PA-CoA) to form 1,2-epoxyphenylacetyl-CoA. The subunit A is the catalytic subunit involved in the incorporation of one atom of molecular oxygen into phenylacetyl-CoA.
Sequence:
MTQEERFEQRIAQETAIEPQDWMPDAYRKTLIRQIGQHAHSEIVGMLPEGNWITRAPTLRRKAILLAKVQDEAGHGLYLYSAAETLGCAREDIYQKMLDGRMKYSSIFNYPTLSWADIGVIGWLVDGAAIVNQVALCRTSYGPYARAMVKICKEESFHQRQGFEACMALAQGSEAQKQMLQDAINRFWWPALMMFGPNDDNSPNSARSLTWKIKRFTNDELRQRFVDNTVPQVEMLGMTVPDPDLHFDTESGHYRFGEIDWQEFNEVINGRGICNQERLDAKRKAWEEGTWVREAALAHAQKQHARKVA
The following text describes a protein:
Function:
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFDWVGLLLKVLYYYGQIIGLINFEIDWQRGRVVAAQRGILFAIAINVLICMVLLLQISKKFNLDVYFGRANQLHQYVIIVMVSLRMASGISAILNRWRQRAQLMRLVECVLRLFLKKPHVKQMSRWAILVKFSVGVVSNFLQMAISMESLDRLGFNEFVGMASDFWMSAIINMAISQHYLVILFVRAYYHLLKTEVRQAIHESQMLSEIYPRRAAFMTKCCYLADRIDNIAKLQNQLQSIVTQLNQVFGIQGIMVYGGYYIFSVATTYITYSLAINGIEELHLSVRAAALVFSWFLFYYTSAILNLFVMLKLFDDHKEMERILEERTLFTSALDVRLEQSFESIQLQLIRNPLKIEVLDIFTITRSSSAAMIGSIITNSIFLIQYDMEYF
The following text describes a protein:
Function:
Sperm-specific microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in flagellar axoneme. Forms an extensive interaction network in different conformations that reinforces the helix bundle composed by other tektin proteins (TEKT1 to TEKT4) and MIPs to anchor the tektin bundle onto the tubulin wall of A-tubule of the sperm flagellum.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MMEFLGTTQTASYCGPRKSCLLPEVAPTSLTHDSYQAYYLPGYRYLSSWRPSLFYKVSSFRPHEDGSGRLLAPLRPPTVLPSVRSALYARYSPQDWYKANANAIKGSEAYRHWAGHLNADSTRLMQDKDQLTRQQQESTGKNIGQRLADIDFWRSELSYELERLVTATRALDTAKRRLECAADEAQGPLQVVLECLYNREKRMGIDLVHDNVEKNLIQETDVIRSCQEKMRKLAERIDQQMAINRDAQHALERDLRDKNSAHFIDEKCYNLRNTSDSINYYHGVEKIDGTVTVPETWAKFSDDNIRYSQNARANTTTLCKEADHVLEVTSDDMWRQWTDTNLAFDSRISEIADSKNQMQAQLAKTLQQIFQTENTIMLLERAIMAKECPLKLAQTRLEARTWRPNMELCRDVPQFKLVNEVFTIDDTLQTLKLRLREAQDTLQLLIFNKAKLEHDLLVKANSLFIDKEKCMGMRKTFPSTPRLVGYV
The following text describes a protein:
Function:
Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids.
Subcellular Localization:
Cytoplasm.
Sequence:
MRAVRRGLREGGAMAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADEKQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSFTILLIHSGGYSQRLPNASALGKIFTALPLGNPIYQMLELKLAMYIDFPLNMNPGILVTCADDIELYSIGEFEFIRFDKPGFTALAHPSSLTIGTTHGVFVLDPFDDLKHRDLEYRSCHRFLHKPSIEKMYQFNAVCRPGNFCQQDFAGGDIADLKLDSDYVYTDSLFYMDHKSAKMLLAFYEKIGTLSCEIDAYGDFLQALGPGATVEYTRNTSNVIKEESELVEMRQRIFHLLKGTSLNVVVLNNSKFYHIGTTEEYLFYFTSDNSLKSELGLQSITFSIFPDIPECSGKTSCIIQSILDSRCSVAPGSVVEYSRLGPDVSVGENCIISGSYILTKAALPAHSFVCSLSLKMNRCLKYATMAFGVQDNLKKSVKTLSDIKLLQFFGVCFLSCLDVWNLKVTEELFSGNKTCLSLWTARIFPVCSSLSDSVITSLKMLNAVKNKSAFSLNSYKLLSIEEMLIYKDVEDMITYREQIFLEISLKSSLM
The following text describes a protein:
Function:
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Sequence:
MQRQLSQPGVVDNDLSDYWTEIKDIEENSESFGSEEDLCKTPDEFEHNTEWLKDSGLTGAASKLSAGNEVHNVYGEVDEVLMSTLTRTQAAAVERRVSNLNQTLRMKGRAQPRDVRDIFQPPSSPTSPTMPQEDAQRGAEGREIIPSPFLPQPREIIPSPPRSISPPLPSPLEDSRHPPVRRRVSSSSSINLGVTDAATGVRTMSVQPKSPGTHKELSRRVSNQELVSDTDISLDFSSDAKLEVGAKSDDEYSADQLPNFTLVKDKYGVTKVGDLSERDMKKVRSLALIELTALFDTHNIELKRRRPGKVKLKESGVFSVPLEVLVEQDQKKRDGIKTPLILQSIILFLEENALNIEGILRVPGSAARIKNLRKDIEERFNNGDFTWDRVRPNDVAALLKQFLRELPNPLLTYEYLSAFASVEHIPDRRQQLQALNLLILLLPTVHRDSLKLLLKFLSKVVSKEKENKMNINNVAMIMAPNMFLVKSGSKNVNYNEVKMAAGTSQIVRMLIKYHKILWTVPSFMVMQVRRLYQVESSKTKDSKGLMKLIGRHHKEKKTTIPSAGQEDPLPKGVIKVVAPHLTKTAMVLDLDPQLTAGDVVKRFRGRTASQDNSSEPGNAPPGCINPRQSAVYARNNTYLYEKGGNIGERCLDMDTNIATLVKVNPHAEWVLKPKSH