lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Exhibits phosphatidate phosphatase (PAP) activity in vitro. May play a secondary role as PAP in plastids.
Subcellular Localization:
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Sequence:
MAASSSLLLLLHCPTCNFYFDSSSYLKRSRLSSYSSIISRGSPLFVSSFGSMTVKRFSSRVGSRSNDGNEQFGALEQESFINNSSEIRKDLVTGGGIEAIVNRLSKWVVSVLFGSIILLRHDGAALWAVIGSISNSALSVVLKRILNQERPTTTLRSDPGMPSSHAQSISFISVFAVLSVMEWLGTNGVSLFLSGLILALGSYFIRLRVSQKLHTSSQVVVGAIVGSLFCILWYTMWNSLLREAFEASLLVQISVFLFAATFALAFAAYVVLNWFKDER
The following text describes a protein:
Function:
Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MPSPYSPRLPGGGGSAYERVTTVNHDDLNPAYPQQPRYHETQQYAQHYQHQAYPQESGYDAPTPALAADNYSPEYSMEDMRKTITPASHRFSITSQPHDYADPDAGWTEKRQSGTQFDQFTPAPPVRSRKKMMWTIGGAVVALVLIIGTVVGIVVARHRNDSNKASTSSASGNTKSLSGDPSKFKKNSALHNSFWGMCYTPFESQFQYGCGVDLASVVEDVQTLSQLTTRVRLYGSDCNVTALMLDAIQRTKVNLTIYPAIYLDSSDPGDVAWNRQVANITFALDSFGTDHIGGISVGNEYLLNGGSATNLLSYVQQFRTLATSKGWTFPVGTADAGSMFTATVAAGVDYFMANVHAWFAGTLVSDGPAWTWQFFEDNDANIAAAAPNTPAAYIAETGWPSGANSTAAATYVNEQGQVTGAHAGVSELQTFLDGYVCEANKNGTGYFWFELYDEEWKDALYGGVEAHWGLFDKTKKLKQITIPNCSHN
The following text describes a protein:
Function:
Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst. They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MDDSRKAYVVAQDLHNAIMQRDAITISEITGRYVSGYREKIALAFMEQYNVLPADLFKEWGTGYFESLMIRCWTNRHEARAKMLKEAIRGALDRDALVDLVILCSTDDWASTLVHYQKHFRIALKADIRLNMPADRPWKALIDRWMEHDRHYRNNVKTDAHMLLQALEGGNGAAIVDILVTTKPQEWEKIVAAYEEHTNKSLETAICMAFPGFEQTAFCAAHYWLCEPSKAAAFLIHRACEGKRGDFRRVCRITSLVLDQCLKCKYVYSVYGHLAADFRKTFSDNTAIPLISLWRAYDIGKILAEKHENIT
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MELDSILDFLDSKTILITGATGFLAKIFVEKILRVQPNVKKLYLLVRATDAKSALQRFNKEAVAKDLFNILKEKHGANLQSFLSEKVTPVAGDITYENLGVKDSGLIEEMWGNIDVVVNVAATTNFDERYDIALALNTFGAINVLNFASKCVQIKLLLHVSTAYVAGETPGLILETPYLLGKTLNDANGLDINTEKKIIEERLKELSYDKTSTDKSITLAMKDLGVERANKFGWPNTYVFTKALGEMILGHLKGDMPLVILRPTIITSTYKEPFPGWIEGIRTIDSLAVGYGKGQLSCFLGDPESIIDAIPADMVVNAMIATMVAHANQPSCEIIYHVGSSVSNPLKYKSIQQSGYKYFSKHPWINKEGKPVIVSEVKVLNSMASFQRYFSLRYLLPLQGLQVANLALCHAFNGTYTNLKRKTNFVLRLVELYKPYLFSKSFYDDMNTEKLRRLVRENEADMFYFDPKTINWAVYFENTHLPGAVKHVFK
The following text describes a protein:
Function:
Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS).
Subcellular Localization:
Cytoplasm.
Sequence:
MFKRLREDIEVVFEQDPAARGYFEVILTYSGLHAVWAHRIAHAFYKKNFFFLARFVSQVSRFFTGIEIHPGATIGRRFFIDHGMGVVIGETCEIGDNVTIYQGVTLGGTGKEKGKRHPTIQDNVLIATGAKVLGSITVGENSKIGAGSVVLKEVPAHSTVVGIPGRVVIQNGVKIGQELNHSDLPDPIFDKLKAMEVELDKLKKQLELKVERKDKNDYSHL
The following text describes a protein:
Function:
Binds directly to microtubules. Microtubule-destabilizing protein involved in the PIF3-dependent positive regulation of hypocotyl cell elongation via the modulation of cortical microtubules dynamic in response to light and ethylene signaling. Promotes submergence-induced and ethylene-dependent underwater hypocotyl elongation.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Sequence:
MESTNLKNAKHETLVMDPISFQSKAQEVSRFSENSNPNFVSHSTPLEKSSKSSAQKNPKWKPNPVPAVFSPRNRIRERRFVVVKKNSRKEKNDSASVDCKCGAKTISNMKKCVCIAYETLRASQEEFFNNRRESVSEIGESSQNLEDGNEQVEFGDSDETRVSLMKRRREKVLEEARMSIPEFGKVMHLVKAFEKLTCFPLSKVTSKEEEDQIKQPLKWELPGMSQPKCSESETDQFTWSSSFYPSSGLILTATNLGLEQPHASVSSSWDNSVSSLNSNGGRRGRRNSFESSASMGSRRSTKKQIKVTSLKPFKLRTEERGRMKEEEFAKKLHEMTLEKAKKRIPIAQGLPWTTDEPENLVKPHVKDITIPVDLKLHSDIRAVERAEFDYQVTEKINLVEQYKTERERQQKLAEEEEIRRLRKELVPKAQPMPYFDRPFIPKRSNKHPTVPRDPKFNIPQHKKIRCCSTSSWSDTGSYMSDLLYQQDL
The following text describes a protein:
Function:
Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Plays a critical role in bone formation and skeletal development. May be involved in early embryonic morphogenesis.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cell projection, cilium membrane. Nucleus. Note=The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner.
Sequence:
MKFSKEIEVFNPPLASSASSGPWVHSVFAFTHSWPRKTLFKRDSAVTHRLYGDISRDFQGTSENGVIFQKCAVVSVQSEWPSAHVRLFVNNTRTPTAANLSDLFLLDNITGLTIRESAGNQTSRGFQAFRKKFLQVGDSFSVSYTASLEARDVGSGDILLLPAQLSFQSSSPNRTQLKAPFTITAEEKITVLPNHGLHAAGFCVAFILSLVLTWAVLFFMVRYQCVKGSSLTRHQVQHHENKLEHSQFTSADGVNEDLALNDQMIDILSSEDPGSMLQALEELEIATLNRADSDLEACRTQISKDIIALLLKNLTSSGQLSPQVERRMGAVFKKQFLLLEKEIQEEYDRKMVALTAECDLETRKKTESQYQREMAAMEEAEEVLKRVSERSAVECSSLLRTLHGLEQEHLRRSLALQQEEDLAKAHRQLAIFQRNELHNIFFTQIKSAIFKGELKPEAAKMLLQDYSKIQESVEELMDFFQASKRYHLSKRFGHREYLVQNIQSSETRMQGLLSTASAQLTLLIQKHERAGYLDEDQMQVLLERAQTEVFSIKQKLDNDLKQEKKKLHQKLIIKRRREMLQKHKEQRREQLSIAEASGAAEDAGQYLGQWRGLMAEHSAALEELQERLDQAALDELRALTLSLSEKATEELRRLQNSGMTQELLKRGVPWLFLQQILEEHSRDLAARAERLEGEERDRGQEGVQSVRQRLKDDALEASTEEQAELRHWEHLIFTKLCSSAFSLSEEELLGMRQEVHGCFAQMDRSLALPKIRARVLLQRFQTAWREAEFLKLDQAMTAPELQPQSKARKPRSKSRSKIDLLKKCTEDKIQLFKEQAPEDLVEKVRGELLRERVQQLEAQEGLFAESLVSLQFQKAARMARTLWAYTALLSIQDLLLEELNSSETLTKSACMQILESHSPELQELERKLEDQLAHQEAAQLQRALDSWQQWAGEGPALLQEPEETDSERHVSAVLQRALSKGQKLLEYHQQSLREEQEDSVVLEDLLENMETDTFVTLYGQELRLASYLSKLTMLPGGTLRRLLTVALPAASQAELLAVLDSVGQKHQDHSVENDGSRVQADLGRRGKHQGWWQALESKLRGELINRGLEKMLWAQKRKESILKKTCPPLRERVIFSGKRSWPHLSLESTDELTPVPIVGAEAVDLLNTGEKLFIFRNPKEPEISLHVPPRKKKKNFLNAKKAAWALGLN
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKSIRVVLAIHSAGMFVLMVLIIVFVFINWAKVRHQVTQLVLIDSELKKHYQIHNETKLILVLALELVVFNILSGVYMAAIKPNNRVVFFVIITLPRIVVSHMFVIFTTIVVVLYQNFKIVNSMVTSDPSRIRHVLLLHKSLTRIGTTINSLFSLQLLVFITINFVVLLGDLYVTLYIILTNNQAKYCTTLIGLIKNCVIVIFELYYLSHVCQNVSTEANRTKFILVSTRIDISDEKKRNLVIGNILRLMHRRFEITALRLFTIDNKLLFGIFGSVASYLFIVLQLEVVPT
The following text describes a protein:
Function:
May play a role in actin filament architecture in developing stereocilia of sensory cells.
Subcellular Localization:
Cell projection, kinocilium. Cell projection, microvillus. Cell projection, stereocilium.
Sequence:
MLKRETKPENDRPRKVRFRIASSHSGRVLKEVYEDGQPAGSLDSECASICGRDGLSESEGQQNGHIGSEGDEHENDEDNLLVLARAASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLPKVLQQPSTDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECTSCGGFGFLPCSMCHGSKMSVFRNCFTDSFKALKCTACNENGLQRCKSCAR
The following text describes a protein:
Function:
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). Binds actin but does not nucleate actin polymerization, albeit slows down elongation by blocking the barbed ends. By promoting actin depolymerization, required for the elimination of presynaptic components downstream of the egl-1, ced-4 and ced-3 apoptotic pathway during larval development.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MGGTSLDPALAEIGKKNGLLVWRINKFVLEPVPEVDHGVFYIGDAYIALYQKYDGCWDVHFWLGKNASTDEIGVAAIKTVEIDDSLGGIPTQHREIQNYESPLFLSYFPDGIRYVSGGYESGYRHVDDQFKNWKPHLFHCKGKRNVRCTEVECEVNSLNLGDVFILDLGKDLYVWMPPESGRLERIKGMARAKNIADHERMGIPKVHILDDVEWDNDSTFWSYFGGVSSVRKVSKGKDDDDNYWKRLTEQITLWKVSDASGAAKVSMVSQGENIRKEQLDPKDAFILDAINGGIFVWIGHECTLEERSKALIWGQNYLKQHHLPRWTQVTRVLESAESTQFTQWFRDWVDEKKKNTFTPLLFQVSDESGLLHVEEIANFTQEDLDGDDVMILDALNSIYVWVGANANANEKKEALNTAKLYLEKDKLPRHKKTAIDTIFQGKEPPTFKKFFPSWDDNLFKNEVRSVQNMRRLLFH
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
Sequence:
MAGTHEVLSRKYRPQKFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCQNPIDNEPCNECNSCSEITRGISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFVLATTEFHKIPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWVAKKGDGSVRDMLSFMEQAIVFTDSKLLGAAIRKMIGYHGIEFLTSFIKSLVDPDNHSKSLEIIESLYQEGQDIYKFLWDSIEFTHTLNLIRDSLADPESVNFPKEDLVKMKSDFENVDSSKLNFLSGKLFEIYERIKTIRLRNSFEIKVFTEIQIKKLVEELTYPSLAGLIDKINHLILMVQGSKNVLSDVNQNTAFALKDTLQPETSKKKDKLSSDVILESQFESNQQDSNLENTKPAELSSRKFDTSTEIKKKFLGTEVDPNQTPKLDS
The following text describes a protein:
Function:
Alpha-transglucosylase that specifically transfers single glucosyl units from alpha(1->4)-glucans to the non-reducing terminal 4-OH of glucose and alpha(1->4)- and alpha(1->6)-linked glucosyl residues. Acts on amylose, amylopectin, glycogen and maltooligosaccharides, with the highest activity with maltotriose as a donor, and also accepts maltose. Does not act as a hydrolase: weak hydrolysis activity is only observed on the disaccharide maltose.
Sequence:
MFRRIAGFSPIFLMLFGSSLPTMGNPVKREIHPDAVFYKEHKLRNDGLVITTNQGNIRLQFKSEAAIEVLYRADSKQLPSFALAQPESAIKAQLTETENHLQFSGGTLTARIQKRPFAISYYRDSELLLAEESGFQVNTDKINFRFYLSPGEKILGGGQRILGMDRRGQRFPLYNRAHYGYSDHSGQMYFGLPAIMSSKQYILVFDNSASGAMDIGKTESDILQLEAKSGRSAYILVAGNSYPSLIENFTQVTGRQPLPPRWALGSFASRFGYRSEAETRATVQKYKTEDFPLDTIVLDLYWFGKDIKGHMGNLDWDKENFPTPLDMMADFKQQGVKTVLITEPFVLTSSKRWDDAVKAKALAKDPQGQPKAFELYFGNGGIIDVFSKEGSRWFSSIYKDLSKQGVAGWWGDLGEPEMHPEDTQHAIGDADTVHNAYGHRWAEMLYQQQLDQFPELRPFIMMRAGFVGSQRYGMIPWTGDVSRTWGGLASQVELALQMSLLGFGYIHSDLGGFADGETLDKEMYIRWLQYGVFQPVYRPHGQDHIPSEPVFQDEETKAILRPLVKLRYRMLPYIYTAAYQNTLTGMPLMRPLFFSDEKNPALIDNKTSYFWGDSLLVTPITQAGVESVSIPAPKGVWFDFWKDTRYQTDGAPLTLPTDLHTIPVLVKAGAFMPYVPAVSTTEDYRSDSLEIHYYADASVPLAQGEIFEDDGKDPNSIKRNQFDLLTLQATHTDNQLHFQLARTGKGYRGMPERRATTLVIHNASDQYQHLDINGKTIAIAQADCASTPALACYDQERRQLQLVFTWGREALNLRLH
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Predominantly nuclear. Localizes to sites of DNA damage.
Sequence:
MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGPHRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPSAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSGSSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPGSPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLAEGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTATGPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MTAPVLGATMLTIALHLVTSGSLATIPEGANKHEHAVLCEVLAIVDADLDIPPQESVDEASYNKIRNLNFSTSTTDWRKTFYSDDALTKPHPEAQPAHKKIADYAKYWPDWHGAATALAATKKPDEVEKAKLDELTHQSRQIAHARVRAIAETARAAKEKALQTAGEAEVIDKAEELKALKTVFFGADSAAAATVTTTNAFGTGTINARQTACEADPADGKAKTLVAQLMCVCTKATQGSALSKACTAAADGSQGWNSGSGSPADTDASAVAKTCANTGESKITATRLRQAITNVAKLVHLTSDGTGYIGVYQATGCTGADNAGMCVKIPNYKSNPTDGIKKLQWTSTLENLANKLEARTRYNTIISKLNEQLRSSSEQAEETIQLTKREEAARSTATKEQTQKSTTATQAQNTLINECEKITKAAQCKEKKPACEWQNKAAEDGPHCKLNATNVEQQATQAGTGDGAAATTTDKCGAAKTPEECAAVKGEIPKDKKAVCGWIEGKCQDSSIIINKKFALSVVSAAFMALLF
The following text describes a protein:
Function:
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
Sequence:
MGKTTSELLIDTISSQVTDVFGIPGTHGLSLYEELRKRVSRGEIRYYMPRLEYGGAIMADYYARLKGNVGVFLSVNGPGFTNSLTALVGAYSEGSPLVLISLNKEFKYRHRRQLHDSGYYDLQLEMARQATKASFRIYSPEDVPIIMERAFKIALEDKMGPVYIEVPVDVLEEKGDFENYKIKKVNRTLIYPTKEEVREALNFLSECSKPILLLGYGASRSNILNYIEKLGIPVFTTIRGKGSIPENHPLYAGTIFNLKEIPGDCLIALGTSFNDLETSRWSIKLPDRILHVDPDVNVFNTSINAEVTIKASAEAFLEEIVEKVNLPKWSYKVEEKNSDIVDNTSEITHDYLAKVLDETLSEDRVIISDAGTNQVMAMDIKVYKPNSYFNSLIFNAMGSAIPASIGGKIASPERQIVSIIGDLGFQGCFNELITAAQYKINFLTVLVEDGVQHFLRLNQKMRYGNTFTTDVFQIDYTKVVEGIGVNVIEVKDRKDLKKSVEEAVGLSLKSPTVLRVHVSPNSIPSRLLMKR
The following text describes a protein:
Function:
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Sequence:
MLDFIRKEADQRSKTLSPDENRDFIDAYLKKINESNGTNESFNLRTLMGNALNLFGAGTNTVRASIEWNLLYCARDPEGVQRKLQQEVDNIVGRERAPEWEDRHRMPYTMAFIWEMLRWRTPTPLGLIRTAERDTTMGGFHVPAGTVVLSNFWAVHHDPEVWEHPFDFDPTRFLNADHTVLLPKPAAFIPFSTGRRMCPGETLAIMEIFIYLTTLMQKFTVLPKEGETISMDIHEGITNIPLYSQELRFLPR
The following text describes a protein:
Function:
Lysis of bacterial host cell wall.
Subcellular Localization:
Host cell wall. Note=Binds to the choline residues present in the cell wall substrate.
Sequence:
MGVDIEKGVAWMQARKGRVSYSMDFRDGPDSYDCSSSMYYALRSAGASSAGWAVNTEYMHAWLIENGYELISENAPWDAKRGDIFIWGRKGASAGAGGHTGMFIDSDNIIHCNYAYDGISVNDHDERWYYAGQPYYYVYRLTNANAQPAEKKLGWQKDATGFWYARANGTYPKDEFEYIEENKSWFYFDDQGYMLAEKWLKHTDGNWYWFDRDGYMATSWKRIGESWYYFNRDGSMVTGWIKYYDNWYYCDATNGDMKSNAFIRYNDGWYLLLPDGRLADKPQFTVEPDGLITAKV
The following text describes a protein:
Function:
Component of an histone acetyltransferase complex.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MKQQSMAISATAGPSRVQPSTTRLKTGGKNAGIGGLPGGVVGPEAAGLDPSGPEHFFVTLAAYADALDALPLDLTRSFSDLRELDAVLGSHLNSLTARLNHLTALIEDPDIDQGQRLLALKEVAEEARAYKMGGEDKIRVALNTAETIISHTDYIDALDAQLDRFGEISTLLNPTKHLKLDQYYVPGQLKDRKLISSLETSTSSAGGAADANGVSGSKKKKVAAHVAAVSAAGGKSHKSADAASAMGSAAVPAGSSNSKKRKAISGAAIGGSSSGGSAKVAKTSGAGKGDEDVKSAANGSSSHKKKTDSSSHCTGASGSKASQSNSNTRLPRAAHAHIGYIEDDEDGPSGRKDATSRRAAGDNDESSSRNRNSRAIRASAAAQRSDDEDEDVDDGDVEEEEETHTRSNAKSRGRAGGRAGASNSRARGAAVATAASPHTGSTSASRADSPASNTGGGGDDADEARYCFCNNVSYGDMIGCDDDDCEREWFHLGCVGLTKPPQGTWYCEACLERRAANGRGSKAKKAKSAGGSKSKVRR
The following text describes a protein:
Function:
Part of the ribosome quality control system (RQC), a ribosome-associated complex that mediates the extraction of incompletely synthesized nascent chains from stalled ribosomes and their subsequent degradation. RqcH recruits Ala-charged tRNA, and with RqcP directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal alanine extensions (Ala tail). The Ala tail promotes nascent chain degradation. RqcP2 (YlmH) overexpression can compensate for RqcP's role in Ala tailing during RQC, restoring Ala tail addition to peptides in stalled ribosomes. Overexpression complements a double ssrA-rqcP double deletion, but not an ssrA-rqcH double deletion; The majority of tagged protein is associated with tRNA-less 50S subunits, suggesting it might also play a role in late stage 50S subunit biogenesis.
Subcellular Localization:
Cytoplasm.
Domain:
Has 3 domains, an N-terminal domain (NTD) which contacts helix 69 (H69) of the 23S rRNA, the central region which contains an RNA recognition motif (RRM) and the C-terminal S4 domain which interacts with the P-site tRNA and H69. The NTD and central region are required to complement a double ssrA-ylmH deletion and to bind 50S ribosomal subunits. The ribosome binding site of the S4 domain overlaps that of RqcP.
Sequence:
MSDIYQHFRKDERAFIDQALEWKRIVQEQYRMKLTDFLDPREQVILSAVTGQADVGLAFSGGYDRAERKRAILFPEYITPEESDFELQAFNVRYADKFVSVDHRSLLGALMGIGLKRQKFGDIVFSETAVQLIVSADTADFVAAQLTQAGKAAVSLEKIDLSDLNIPAVDVEIRDDTVSSLRLDAVCASMSRQSRQKSQTLVKNGLVKVNWKVVEDPSYIVAEGDMLSIRGFGRCSLTKIEGKTKKDKWRVTFERQK
The following text describes a protein:
Function:
Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MSNYYNKNKKSYSDVELPTNPNLPSWIITPKEEKAVFERWRKRAFARCDELINKYIECSNSYSNPVDAVKKCQKINEESLACVAQYQTKEYLDIEKDLFIKEKLEKKKLYKLYLEKQMQEKQQQQQQEKQG
The following text describes a protein:
Function:
Catalyzes the conversion of methylthioalkyl glucosinolates of any chain length into methylsulfinylalkyl glucosinolates.
Sequence:
MATDRPKEKVCVVGAGMSGLAAARELRREGLEVTVMEQRGDVGGQWLYDPRTDADDPLGATAPVKVHGSVYASVRLISPRECMGLSNFQFVPRPGRDARRFPGHREVYWYLKDFCAAFGLEDAVRLNTRVVRVAMAPPREACSGDLKWLVRSVHVEPNGSEDGVAVEEVFDAVVVASGHYSQPRLPSIKGMESWRRRQLHTHSYREPEPFRGEVVVVVVVGCGASGLDIAMELCGVANEVYLAAKSVEDAARPPPAVSKMLANHADIRLHPPVDQLCDDGTTVAFADGSRAAADAVIYCTGYRYSFPFLDTGGIVAVDDGNRVGPLYEHTFPPALAPSLSFVGVPMWVFAPWFFEAQARWVALVLSGKAALLPEEEMLRALHEDYRAREIAGVPAYHAHAITAEVWEFVYWHSDLPRMEDWKVELFTTSILMNLREDRETFRDRDDDSESVREGLRR
The following text describes a protein:
Function:
Involved in ribosomal large subunit assembly.
Subcellular Localization:
Nucleus.
Sequence:
MTETVKASDILNKSLSGHLVEGEDTLLYDLGNLCAFDHSSIDKNEYKENPTKYINELARKNVQLLISRLFQLPIKSIEEGSLALLPKCETKIPRERSVPQGKQKTRWEAFAELKGIKKQKKSKMQWDEKHQEYRPSYGYKKANDDSGEYIIEGKQSDKVGDDPFQKKEEEKNQKVQKQKKREQRNFDEASMRQMGNVGKSLTFSQENRPTIKSDMEKVFDVAKLSTASLGRFDKKVENEKDKTKRGNKKLAGLGADNVQKESESNQKLVDRMFKKEDVLNVDKAVRQEVKSQERENYSNKRRDFKQGGGSNKRFKK
The following text describes a protein:
Function:
Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').
Subcellular Localization:
Nucleus.
Sequence:
MDPGAGSDSSLTVNEQVIVMSGHETIRVLEVGVDAQLPAEEESKGLESVAAGGSQSGGPVEASGPAEAGSCDPDHSAEATVAARSPSESCPSDCHLQPSPEPASGITDPDAAGCTSCPPGQVAGQQGLAVWTIPTATVAALPGLTAASPTGGTFKPPLAGLQAAAVLNTALPTPVQAAPPIQASSPAQPRPPAQPQPLFQTQPLLQTTPAILPQPTAATVAAPTPKTVDATPQITVQPAGFAFSPGIISAASLGGQTQILGSLTTAPVITNTIPSMPGISSQILTNAQGQVIGALPWVVNSASVATPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPQPVAVRKPNTPESPAKSEVQPIQPTQAVPQPAVILTSPTPALKPSAATPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVLEKWLMEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQIP
The following text describes a protein:
Function:
Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity.
Subcellular Localization:
Endoplasmic reticulum. Cytoplasm.
Sequence:
MSSSGAMPAVSSASSSAAVGILSATTAKTKTKKKHFVQQKVKVFRASDPLISVFMWGVNHSVNELIQVPVPVMLLPDDFKANSKIKVTNHLFNRENLPSHFKFKDYCPQVFRNLRERFGIDDQDFQASLTRSSPYCESEGHDGRFLLSYDKTLVIKEISSEDVADMHNILSHYHQHIVKCHGNTLLPQFLGMYRLSVDNEDSYIMVMRNMFSHRLTVHRKYDLKGSLVSREASDKEKIKELPTLKDMDFLNKSQKVYVDEEQKKNFMEKLKRDVDFLVQLKLMDYSLLLGIHEVFRAEQEEEEDLEEDHTENESSPHMNVGSYGTSPEGIAGYLNSHKPLGPGEFEPIIDVYAIKSSDNAPQKEVYFMGLIDILTHYDAKKKAAHAAKTVKHGAGAEISTVHPDQYGKRFLEFVTNIFA
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MTDAEAASGVVDSVYFSFYTSEEVRKISVKKITKPDLLDAKNSPVPDGLYDPALGPLNDTDSCKSCGQLSVCCPGHCGHIDLARPLYNPLLFKTLQGLLQITCFFCHKFKINEEKVKRYVALLDLIVKGDINGARSLEANSWSEIFFPEEGTAESVTPSNFDKAKHLTWTSLQQSEALSVLSKFMRERRKKCDNCGKKNPTIHSPIFGWLNKTTQGSDIRANFIIDSNLDLSSSEAKYSSLTQSRGESASEMDEESPLPQKKVKEDKELCDLPPEFIKQMSSSGQKHLLPSEVELILNNLWKNEANLCMLISGIHCKSSSISRGNKGCAMFFLKTLLVPPSKFRPAARTSGRGVLEHPQNTLLSKVQQANIGLKNCIIADLDHPDILRRWMDLQKTVNVLFDGTKGFAKSDKEASGIRQLLEKKSGILRQKMMGKRVNFACRSVISPDPYLAVNEIGIPPYFALRLTYPERVTPWNVNKLRCAIINGANIHPGATHYKDKERMYKLQASQTMRSAISRKLPTSRGMTAQLGMGPESEFEGKVVYRHLQDGDIVLVNRQPTLHKPSMMAHVVRVLKGEKTLRMHYANCSTYNADFDGDEMNVHLPQDEISRAEAINIVNANKQYIVPTSGHPIRGLIQDHIVSAVLLTKMDTFLTREEYHQLLYASCVPPTSYSQRNGFGQKVSVSWSDYEIQPLPPAIWKPTPLWTGKQVITAILNFVTRGHLPLTIEKRGRIQKEYIGEDHTLLVLHIHNNDLVHGMIDKAQFGTYGLVHAVHELYGPDVAGMLLSVFSRLFTSFLQMHGFTCGVDDLLLSQKSDMERKKILEKSETQAEEVHMRFTRTKDGDGDPMELQREIEKVLRGNGDSATALLDRMMSNSLNSLTSEINQTLFPNGLSKPFLKNCLSLMTTTGAKGGLVNMTQISSLLGQQELEGKRVPRMVSGKTLPCFPPWDISSRSGGFISDRFLTGLRPQEYYFHCMAGRDGLVDTAIKTSRSGYLQRCLIKNLECLKVSYDHTVRDADGSVVQFIYGEDGVDVLKTSYISEFKMLSDNRNVVLQKFSDQIVDTSLAKSNAYIRELPCSLRDNATDFVLKKQKSSPHQINKKDFMKLMKLKYLSSLAEPGEAVGVVAAQSVGEPSTQMTLNTFHLAGKGDMNVTLGIPRLQEILMTASKDIRTPLMNCPLHAWKTKDDAERLAAKLRRVSVADVVERMEVCTVPFSIHRNQISTIYKLKMTLYPSELYPSFSELTLEDCREVLEMTFVEAMEDAIAKHVDTISKISDIKVVSGKEENDFEEGVDEDESRNKSSMEENADGGDEDDESGDDQGIDYKRRKQQANDEVEYDDGIEKESFVAAGEHDEETQSGFESEIDHLEADEDYLMGGGSPGVDMDLATPESPSKADSTPISEDDKKKSKSVEKGKKETKSKAKKPKRSKKKIRRTIYVMAEGLKFEVHYIFRSEPRILLAEIAQRTAKRVYVKEYKNIERCSLKENKKSTDPFMLQIAGVNFKTLWDLEEYLDINHIYSNDIHAMLNTYGVEAARATIIQEVTDVFGLYGIQVNIRHLSLIADFMTFHGGYRPMNRVGMGDFNTSPFGKMTFETATKFIVESAFHGEVDTLESPSASVSLGQPVKMGTGCFDLMQNLQL
The following text describes a protein:
Function:
Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MENSLGCVWVPKLAFVLFGASLLSAHLQVTGFQIKAFTALRFLSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKRQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEVKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSVTDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLNLDTMYYFRIQARNSKGVGPLSDPILFRTLKVEHPDKMANDQGRHGDGGYWPVDTNLIDRSTLNEPPIGQMHPPHGSVTPQKNSNLLVIIVVTVGVITVLVVVIVAVICTRRSSAQQRKKRATHSAGKRKGSQKDLRPPDLWIHHEEMEMKNIEKPSGTDPAGRDSPIQSCQDLTPVSHSQSETQLGSKSTSHSGQDTEEAGSSMSTLERSLAARRAPRAKLMIPMDAQSNNPAVVSAIPVPTLESAQYPGILPSPTCGYPHPQFTLRPVPFPTLSVDRGFGAGRSQSVSEGPTTQQPPMLPPSQPEHSSSEEAPSRTIPTACVRPTHPLRSFANPLLPPPMSAIEPKVPYTPLLSQPGPTLPKTHVKTASLGLAGKARSPLLPVSVPTAPEVSEESHKPTEDSTNVYEQDDLSEQMASLEGLMKQLNAITGSAF
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs) (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSAPAGRLQPQRFAALPNPVTAENKFWRSFKVPVVAKEYSAITSIHFSAESPYDFAVTSGARVQIYGASSRSVKKTIARFKDTAYSGNIRKDGKLLLAGDATGLVQIFDLSTRSILRALDAHQFPVHVTQFCPYANTTFLSGSDDKTVKVWDLSTGAVQYDLSGHEDYVRTASWMSATRLVSGGYDGTIRLWDTRIADPEVMSFSHGEAIDVVLPMQSGSTVISAGGPSIKVWDLVAGRQTPTKKLSNHQKSITCLAMNSENTRLLSGGLDGHVKIYNISDWKVVHGMKYSGPILSMGLSPDSCNLVVGMSNGTLSQRTRRITKQTSSKTPFLGGVGSAFGVVGKKKQIYKGENDEFYVEEARRKRLRPFDKALKSFCYSDALDMVLENGSPVLIITMLIELLHVGGLRIALSNRDDLSLTPLINFLRKYIRDPRFSETLCIVTSTILDIYGAALGGSVMVENAISKLREKVEQEVAVTQRANELVGMLQMLSA