lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for loading and maintenance of stable association of CDC45 with chromatin during initiation and elongation of DNA replication. Also involved in temporal regulation of origin firing. Required for the association of PSF1 with origins.
Miscellaneous:
MISCELLANEOUS: Present with 125 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
METWEVIASVKEATKGLDLSLDHPLIIKSEDVPSNILQLLQQKNRRQLKHICMKSRKEYFLLEEYGPGFWVKWPYNYFNGYSLPERRTEVVTTVERERAKRETLKTWDELKFKELLHLWSEEPKGSCKLEKDKDLKLDMNPPDMKGESKINDYYSDPKEYIESKYYDALFSIHTPLAYFVKSNLVRLKNTCRTKYGSDSYKIAYQAMLQKFLLSIVQFKDRHDNRLLLEPFSSPIADEKRKNCLTKFVIQDENKNSSTIADLCVVLKSREIKLQILLLLEIIGLNDLDWNFRDFEKKYKLKLKKRSLNLTKKGLVRRRSKKKTSEKDKGIERITTSLDYCEQLDLYLDRACILDILLSSETPNPDAIEASNGTIQEHKKNILDKSKEASLVGFINYVLIPYFNKKVPHAVEFIIQKLKGPSMRPKRALKKVNDSTNVSSPNTVETYNRLSTSQRASRSSIINSVPSSPALRRVDANLFSRKSIASPTPELLNSRTNSNLNEFLESETRSLKRPSQLGRTKSDLTMNHLQKRQFSVSDLSTTRVPNSSTITLKTPFSHSTINAYKTMNNSFRRVGKRKDINETIRLHERVDSEENVQVQATPAVKKRTVTPNKKAQLQSIIESPLNFKDDDTHEGRKNTSNITSTPTNKPPENSSKRRVRRRLFAPEST
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSLKSVNLVLKIGSLLALTPAKIKKNRVLFPSKAYAFFWIILFLTGVSVSAFYRKALYEEYSTIRIILQVATDIILLILNISTIVITRIKKHQWNKFIRILQTLKSNKESFSFLPFFITNVVLMIMLTYETYLWSSIMGVEYYEMYAVEYFQTYAQFIVYYLIYAFLNLILDRAENLSKKVSFLKLNRLNFNLKKIIKSDFCALAECLDTFNDIFGWLILLLIGFCLLQQLTYLHNLIIQPEIQEVKIIIYEIIYITWHMVGTFSSVFICDLIQQKVRNIETAASSSDENEFKESKKLRNVIVNDHFPHFTAAQFFDLNRKTILGVFNALVTFVIVAIQFDSVGV
The following text describes a protein:
Function:
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
Sequence:
MSHHPRMAEMKYVVVTGGVVSGLGKGVTASSIGLLLKSCGLRVTSIKIDPYLNMDAGTMSPFEHGEVFVLDDGGEVDLDLGNYERFLDVTLTRENNITSGKIYQAVLENERRGDYLGKTVQIVPHLTDVIQDRIQSVAKVPVDGTPNPPDVCVIELGGVVGDIESMPFIEALRQLQFYVGAENFCHIHVSLVPVLGVVGEQKTKPAQQSIREVRAFGLVPHLLVCRSAQKLEDYTKEKLSQYCDVLTSDILNIYDVSNIWHVPLILRDQEAHYAVLSRLNLSPAEPCVEKWSAMARSCENLTVPVRIAVVGKYTGLADSYLSVLKGLQHACIACSRRLLVDWVASSSLEDAKRHDMAEEYESAWSMLKDADGILIPGGFGARGVQGMILAAKYARENNVPFLGLCLGMQVAVIEFSRSVLNLENANSTEFDPATPYPCVVFMPEVSDTHKGGTMRLGSRATLIQTPHCITAKLYQKETHIYERHRHRYEVNPQMVEALEGAGLCFVARDETGRRMEIMELPSHPFYVGVQFHPEFKSRPGKPSPLFIVGGLFILSAA
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MADGKGESRTGLASNDKSPSTLSAASTHRLIDDLKELKDMLKDDDVSALSSSVYCGRFCEILMQHTEESTASENVITCAGVYGTALQSFATARPYLTTECEDVLLLLGRLMLSCFEVILSMTEDDLSCDYGLQLKKSIVESHNILVEFGNNNLQLLIDVVQNGGAWKNHVLVRILSQQPVEPEEVQKLISQEGSCFLQMRIKHLMKSNCIQQAMILSKICSDSAEMSNDFFFRQSFITCLCTMLPNEEAFKEISKMDGKEVLDTICNLESEGQDNTAFILCTTYLTQQLQNEITSCSWELTLFWSKLQRRIDPALNTFLERCRQFGVIAKTQQHLFFLIRVVHAEAGDEGIPIAIVLCIRALQIPSNESDATKTSVCKTIACLLPQDLEVRRACQLTEFLCEPTFDGLNILEELFQQPDQKNDEESSVISNSLRCELLLALKSHWMFDPEFWDWKTLKRHCLKLLGKEVSDEEEVNFDNPLVNETDVFNPSLGSYEDLVEKAQASPEYVTNELETTKVKKPVGSSERYKRWLQYKFYCLICNREVIEARILHHSRMHFADGIYTCPVCIKKFKKKDIFVPHVMDHMKMPMRHRPKKDKIQELKPDMNSAEDACDTMGYISFKTIQDKQLQDRDVYPCPGTGCSRVFKQFKYLSIHLKAEHHNSDENAKHYLEMKNLREKCAFCRRHFITGFHLKQHMRIHLASQPFLCASIDCNARFNTINELLIHKQSHPDPQYTCELEGCNLVFGDLGLLYHHEAQHFRDASYVCSFSGCKKFYYSSTEFQEHLVTHTKDSNNSKNAINETTCKLENNHLPPLNNEAYTLSDLDDVCGNSPMLQDRNMVPEKKLPTEAGDISCKQIHFCSSSHKPSEHLPTLTNCLKNSGGVHCTCKIANTVKVSLQRIDPLQFPQSLAGYSTVNTTDRKSKESTVAGTPKTPLLPETEHLNCVPSSDKTNSANECDEAHFSSGCHRSASENTINELLTSLKHLNLKNSNSCINTSGAQDSEGNASSSIDCCVPKNPLPQKQEKVSQYLTQLSCKPYLCELKGCTFAFATKDALLVHYVKKHHYTRERTLKLQIFQNKYTPFQCHICQTAFSRRTLLRIHYKKIHHLSKERGTRMLENNIKTHMDERHNNYIKFQENEDNTLIQERRSLIQELNNETYTDSLSDETDAGNGTGTSGSHSDNFKGGEERGRRRVVAQGKLCYILNKYHKPFHCIHNSCNSSFTSQKSLVRHYQLVHQYNKESLCLEKDKVDTRREYGKCRRIYTCKYKECRKSFICARALSKHYTEFHNHGENEEKELDDAYADNSSKPQTDDEKSSDETESDESEIYCDVEGCSAMFSDHASYTRHILSRHRRYKLYQGQRKRRLTVEQDEMQGNYIASRHGNNLVFNRKKRRVRKKEDQKESAELKSREEALQMCAQNIDITQFPCMVHGCSSVVKLESSIIRHYKLTHNLSATYVTDNTSKLVYCVKNFPHCKTEQDFSTEDHSPEMQYLIQEQKIPKLHLHGDIYNKCDQSDGVHVQSNKSDLSSSVEKVALNQDKMLHGCLRQSSMQSSPIECTSSSAEPSFASFHSSNMDNEMLQNSVDSDSLNSPNVDSEGQLTLNLKASFKPNGFESSFLKFLQETRDSDDEFEDAEWKPQQHFKLQNSVQTKKLRETSRNDKVCLPQDKRLGHDDLQRLRPLLSSNVQTATSVPTLQTLRTILDKALTNCGDLALKQLHYQRPVVVLERSKFNIPLIDLFSSKKTDELCVGIS
The following text describes a protein:
Function:
May displace the NuRD complex from chromatin.
Miscellaneous:
MISCELLANEOUS: The MBD3L proteins are encoded by strongly repeated regions of the 19p13 chromosome. The exact number of functional copies is unclear, and some of them may represent pseudogenes.
Subcellular Localization:
Nucleus.
Sequence:
MGEPAFTSFPSLPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRSPLEPTPGRFPAVAGGPTPGMGCQLPPPLSGQLVTPADIRRQARRVKKARERLAKALQADRLARRAEMLTGG
The following text describes a protein:
Function:
NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism. Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (By similarity). Wallerian degeneration is triggerred by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADPR (cADPR) and nicotinamide; NAD(+) cleavage promoting cytoskeletal degradation and axon destruction. Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (By similarity). Can activate neuronal cell death in response to stress (By similarity).
Subcellular Localization:
Cytoplasm. Cell projection, axon. Cell projection, dendrite. Synapse. Mitochondrion. Note=Associated with microtubules.
Domain:
The TIR domain mediates NAD(+) hydrolase (NADase) activity. Self-association of TIR domains is required for NADase activity; The ARM repeats inhibit the NAD(+) hydrolase (NADase) activity by binding to NAD(+): NAD(+)-binding to ARM repeats facilitates inhibition of the TIR domain NADase through their domain interface. In contrast to classical ARM repeats, the last helix of ARM 6 does not fold back to interact with the first two helices, but instead turns towards the N-terminus of SARM1. As a result, the two following motifs ARM 7 and ARM 8 reverse their directions and lie perpendicularly. Moreover, ARM repeats interact with different domains not only within each protomer but also of the adjacent ones.
Sequence:
MFLSLVVYLSKICRYLSMFSSDRLTVPEYVSSRLHNRRTAPDPRAVSPGISTDVQAVLDGSLPALRSAIRTLRSSKDTGDLEETRRAIAETFQLVEEAWVLPTVGRRVAEEICNRIRLDGGLELLLQLMQTPAVEITYESAKLLEQILVSENRDYVARMGLGVILNLTREQEDAQLARSVSGILEHMFKHTEETSAQLITNGALDTILYWCRGTDPTVLRHCAVALSNCAMYGGHRCQRLMIEKQAAEWLFPLAFSKEDELIRFHACLAVAVLAANREMEKEVVKSGTLELVEPFIASLDPDEFARNMLDSADSMQGRTAADLQHLLPLLDGTRLEGKCIAAFYLCVETSIKSRQRNTKIFQEIGAVQSLKRIVMYSSNATVCSLAKRALKMMSEEVPRRILSSVPNWKSGEVQTWLQQIGFSAFSERFQELQVDGDLLLNITEQDLIQDLGMTSGLTRKRFLRDLRVLKTYANYSTCDPNNLADWLADADPRFRQYTYGLVQSGVDRNNIVHITDQQLLTDCHVENGIHRAKILSAARRPSKPCLTDSQPKGPDVFISYRRTTGSQLASLLKVHLQLRGFSVFIDVEKLEAGRFEEKLITSVQRARNFILVLSANALDKCMGDVAMKDWVHKEIVTALNGKKNIVPVTDNFVWPDPTSLPEDMSTILKFNGIKWSHEYQEATIEKILRFLEGCPSQEKPDGAKTDKKEPQKK
The following text describes a protein:
Function:
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
Sequence:
MLSKPGLGVYLVASWPSKDTYEKAIRGLEGIADFFELGLPSKNPKYDGPFIRKAHREAGEPLWLRPQAPTYIMTYWEEHRGNLDGLFTLAAEIRARGVLAPDLLIDFPEELELYLKYAREYALAPAFFVPGKFPHWLVKRLTSAEPDFIYLGLYAATGVELPVYVERNVKIIRQLAGDVYIVAGFAIDSPSKAARLIEAGADGVVVGTAFMRRLQNSVDSALSFLKSIKEALK
The following text describes a protein:
Function:
Probable GTP-binding protein. Functions in innate immunity and more specifically the inflammatory response as a regulator of the Toll-like receptor TLR2 and TLR4 signaling pathways. Negatively regulates the part of the TLR4 signaling pathway that leads to the activation of the transcription factor AP-1. By retaining the phosphatase complex PP2A into the cytoplasm, prevents the dephosphorylation of the AP-1 subunit JUN which is required for proper activation of the transcription factor. Both inhibits and activates the TLR2-dependent signaling pathway. Positively regulates the TLR2 signaling pathway to activate specifically the downstream p38 and JNK MAP kinases and promote the polarization of macrophages toward the pro-inflammatory M1 phenotype. It may also play a role in the regulation of inflammation induced by high glucose through the PKB/AKT signaling pathway. Also involved in erythrocyte differentiation through activation of the ERK1/ERK2 signaling pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MAGMDSGNLKTARLWRDAALRARKLRSNLRQLTLTAAGACPGAGADALESPASPQLVLPANLGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWKIKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLKLLLMGHKAAGKTLLRHCLTEERVEGCPGGGDKEKCYPPSPPPVSKGIEVTSWTADASRGLRFIVYDLAGDESYEVIQPFFLSPGALYVLVVNLATYEPRHFPTTVGSFLHRVGARVPHAVVCIVGTHADLCGERELEEKCLDIHRQIALQEKHDAEGLSRLAKVVDEALARDFELRSASPHAAYYGVSDKNLRRRKAHFQYLLNHRLQILSPVLPVSCRDPRHLRRLRDKLLSVAEHREIFPNLHRVLPRSWQVLEELHFQPPQAQRLWLSWWDSARLGLQAGLTEDRLQSALSYLHESGKLLYFEDSPALKEHVFHNLTRLIDILNVFFQRDPSLLLHKLLLGTSGEGKAEGESSPPMARSTPSQELLRATQLHQYVEGFLLHGLLPAHVIRLLLKPHVQAQQDLQLLLELLEKMGLCYCLNKPKGKPLNGSTAWYKFPCYVQNEVPHAEAWINGTNLAGQSFVAEQLQIEYSFPFTFPLGLFARYSVQINSHVVHRSDGKFQIFAYRGKVPVVVSYRPARGVLQPDTLSIASHASLPNIWTAWQAITPLVEELNVLLQEWPGLHYTVHILCSKCLKRGSPNPHAFPGELLSQPRPEGVAEIICPKNGSERVNVALVYPPTPTVISPCSKKNVGEKHRNQ
The following text describes a protein:
Function:
[GLV3p]: Signaling peptide (root growth factor) required during root gravitropism in a PIN2-traffic dependent manner, thus influencing the formation of auxin gradients. Maintains the postembryonic root stem cell niche.
Miscellaneous:
MISCELLANEOUS: 'Golven' means irregular waves in Dutch.
Subcellular Localization:
[GLV3p]: Secreted.
Sequence:
MMRFTIIVIAFLLIIQSLEEEHILVYAHEGGEAGHKSLDYQGDQDSSTLHPKELFDAPRKVRFGRTTRAEKEQVTAMNNDSWSFKISGEHKQTNILADHDTTKNTFCKKMMIIVNDLTSLPTLEPSTSTNDMEKLARLLRDDYPIYSKPRRKPPVNNRAPDKF
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP192 is located to the NPC core at the nuclear membrane and is essential for de novo assembly of NPCs.
Miscellaneous:
MISCELLANEOUS: Present with 2520 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nuclear pore complex. Note=Cytoplasmic and nucleoplasmic side of the nuclear pore complex in the nuclear envelope (symmetric distribution).
Sequence:
MKWSAIPFQTLYRSIESGEFDFDLFKEVLPDLQNLNLNTDKLKNNASRSQLEKGEIELSDGSTFKVNQEFIFEAISLSDELNLDEIVACELILSGDTTANNGKVQYFLRRQYILQIVSFIVNCFHEDTELYQELIKNGALVSNILSAFKFIHTQLSEIKQQINKAQILENYNALFQQNIKFRRDFLLREYDILSQILYGLVDKGAIMKNKDFILSLLHHVSELDSNDFFIIYYTPAFFHLFASLRVLPDADVKLLHSQFMKDLKDDSIYTKPVKVALIFIFFAYFIGWCKEDPKRRADTMDFKTDVDEPMTSAVELGAIEQILIFAADTSIVEQDKSMELFYDIRSLLERHIPRLIPKQLLDDEKIFSQTTNSTYNPASATDNMSGRGLWNPSYPGMMSTTGTARLNSMPNNVNEYSYTTIVLSDQTQEFFLSSFDDVLQTIITDCAFLLTKIKDAEEDSLLSGEDLTLDDISLKADLERFFLSIYFFYASRPEYSCTFWSDKESNAYGFIEWCSRCNDNLMRSCFYLMVSSLSFGPENALNVYHYFGENSSISWKNIAQCLSDYTKKISNFNSSLHKRQQFSESTHNDIDSTAVALEEGLNEEAVIFLSSLLTLVGSVTYQVDEDVKSSLSKVFSDVLFEFTKINTPLVGAAFKVISNLVPKLESSRTKFWSFLDSLIFKDSSLNYSSESYRNAFTNVLTKYSDVLGFLQLFHNLISIHSRENNSEYMVFGKLAFPTRLGQGYRKVGIWPYFDYIFNDILAHVDQIVDIRNKRAVQLPILKIIYTGLCSFDYSVILNSIPAAANLDALVDCENFFNYVQECPAIPIFNYIFTEKIYKSIFNVVDVGVDQLSIELEGGKNQAELLQLAVKIINKVLDYQETYVEELFPIVKKHGKTDYFLPKNYSLHGLRSFYDAIFFNIPLVAHLGLYVGVDDQILATNSLRILAKLSERSNGSVASLSKRNKLLTIFDSVDESARIKDAFITQLESSITDAGVLALKLELLDFLTSNLSNYSRTMTISHLLLGFQVSNVISLGPNLATFISSGTSLLDSLISVLEASLNSITKDNIDYAPMRLATAALEIILKLCRNPLTSGLLYSYLIKENFFERIMILDPQVTRFTTWNGSPFDNSTEEKCKNFIESESVGAFLSFLAYRNYWTQYLGLFIHKISFSGTKSEVLTYVNYLISNTMYSVRLFSFLDPLNYGNICEPKETLSIFTNVPLNLEQVTLNKYCSGNIYDFHKMENLMRLIKRVRAESLHSNSFSLTVSKEQFLKDADVECIKAKSHFTNIISRNKALELNLSVLHSWVQLVQIIVTDGKLEPSTRSNFILEVFGTIIPKISDYIEFNITFSEELVSLAVFLFDIYNRDRKLITDKGTVDGRLYQLFKTCIQGINSPLSSVALRSDFYILANHYLSRVLSDQVGSEKVLQDLRLGSKKLVEIIWNDVVYGEGTSRVTGILLLDSLIQLANRSKENFILDSLMKTTRLLLIIRSLKNTDALLNSTTEHINIDDLLYELTAFKATVFFLIRVAETRGGASALIENNLFRIIAELSFLKVDPDLGLDLMFDEVYVQNSKFLKVNVTLDNPLLVDKDANGVSLFELIVPIFQLISAVLVSMGSSNKAVVQTVKGLLNTYKRLVIGIFKRDLLREKEDKKNSSDPNNQSLNEMVKLIVMLCTLTGYQNND
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Sequence:
MLSIRNLSKTFSSAAEPVHVLRGVDLDLKAGERVALTGESGSGKSTLLHLIAGLDAADGGSIRLEDTEVTKLSDAGRASLRRDRIGLVFQQYNLIPSLSVADNLAFQARIAGRHDAAWSSELVERLGLGALLKRYPEQLSGGQQQRVAIGRALATRPSLLLADEPTGNLDEATAEDVLALTRDLVTRTGCGFLMVTHSLHLAGTLDRHLTLHAGRIA
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSESWQQPPQTQPQQPQAPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQPPQHAPLQAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSSHTGMVKCSICDKTYKPAEAAEPATTTAPSLPSAPPPTNVAPVEQPEKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKCLPGSTERPFKCPVCNKAYKRASALQKHQLSHCAAAEKPLRCTLCERRFFSSSEFVQHRCDPTREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP
The following text describes a protein:
Function:
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
Sequence:
MVIKFDLIAAACENMGIGKNNDLPWRLKSELAFFSQMTTQTSDESKKNVVLMGRKTWDSIPPKFKPLHQRFNFIMSRAGVNLEGYKDCFSFKSLDEVISKLQDEKFQQLYENVWVIGGSYIYEATMASKYFHRLYLTKVLKTFDCDTFFPKIRDDLIEVRDPRVPEGVQEENGIQFVYHVYQNPDFNKL
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MEPNRRLRYFRSEIPQPVTEHRFPKRVEKLVFSVLSSNALMKLSEVQITTPILYEHYPSPATNGVLDKRLGLSDKVGKCATCGKDTKMCIGHFGTISLALPVFHPGLINDARTMLSIVCPFCSRVKISEADRLKYKVLNHKFSLAIVKEAQEQAKKQVNCPFCHAPSTICKKSQGFRVLREMHYEERATKILADVIKHQKDIEKIQELDQRLRNHVVDPIQALHILQKVPECDYPYLGIPWQSRNVYASQQTPDSIASNDASQLFSRGSSKLLARTASRFIAQHQGISDRATRLTSHAFLTRPQDVILTHIPVPPSCLRPSVQSGSGAGTTEDNLTSHLVRILTINDKLKEAMVSGAVATSKVYAKWDQLNMDVSLLYIGKIPGGVQPVKNKTDSGTKEGTGIIDRLKGKAGRFRSNLSGKRVNFSGRTVISPNPYLSMQQVAIPRLIAQNLTFPEIVTSRNIRFLRELILNGKTYPGANEVLLLNDTIRYNPALKRLGIDVKQSRDMEAKAMELVSRCVDTFNLNSLCADLPELQAAIQHLVSESSNAINSELKAEDLPQNQPLFAKEVYDPAQKGESNNIDNNVCEIDELKLEDTADYQVGESAGQASTVAVEQPPESRTVLKLNSIASLQLTNASSQHLSTFKLNTVSLLQKDRRGRQAIANSLRPNDIVYRHLLPNDTLLFNRQPSLHRMSIMQFNAVIHENRTFSFNPVVCSPFNADFDGDEMNIFYMQGQEARAEAGILMGSHENIISPRHGECMIGLTQDFLTGIYLLSGKGIFMTRQEYCQHVSYGCDGFGDATYGVSLYNYGREFIKSIHDRRGTEEDTVGFVKVPCLSQPCIVYPRQLYSGKQVLSVLMKGNDFDSVNINLEHGDKTYKKDSDRRALSVNDDYIIIQNSEHLVGRLTKTFLASSKNCIFYFLVQNYGPVSAARIMLRFAKVAARFLMNYGFTIGIDDVMPSQRVLGKKEVIVQEGYEKAQEKIRDYESGKLEAIPGSTVQETLEATLNQILSNVRESCAQIALKELHFTNKPLIMSLCGSKGSPINIAQMIIILGQQSFGGSRAPDDFYTRSTPYFYHYSKEPNAKGFILNSFYTGLLPFEFLAHARAGRDGVIDSACKTADTGYLQRRLVKCLEDLSVSYDFTVRNSKKSVVQFRFGHDGFDPIKLEVGTGQCFDLDTLLRHIILLNRSQDLAEGAFPVLLDRYKAEAELDVLLNKDFYGQEACLIERSNVTSYFQQSILPKLTTNTHIATTVAPALAASFLQTTLTKKDIDDFLRQVRRKYIRLNLEPGSPCGAVAAQSVGEPSTQMTLKSFHHAGLASMNITQGVPRLKEIVDGVVKISTPITTVELHVDVDKEELAATVTEKYLEKARMMKNIIECTYLGQISASIIECYSQSVCHIEVNLDMKIIADMGLAGIITVETVVASILHNDKAKKLVGQDQSSGSVSIHSATRFSVRPLTQSRDDLLFDIQSLKLLLPMIPVSGISTCSRAVINEYKEFCQGATSSAPLTKYNLLVEGIGLQNILNVSGIDFTRTLSNNIVEVANTLGIEAAVATISNEIKACMDSHGMAVDMRHIRLLADIMCFRGRVLGFTRFGLTKMKADSVIMLASFEKTGEHLFNAALGNKVDEANGVTESIILGKPMSMGTGSFSLLQAPYFDEKTGKTIEYQPKQTTRFLGEVLNKQYDEEVDAIVNAFWYDEKLYLTGAEAKAKLLRGRRHANKRSWSRGKERHASLKPKNR
The following text describes a protein:
Function:
Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Sequence:
MNWTSLVYLWFIFKSIFADLTSHQLKSKVVFLDTTISDEVARSYLGSEDGNVTHGNYEILSIANGANDGNITSYLCQLPRTKKMAPTKPKPTMSVHELKSRAIDLISESFVEGTSCVFSFNLHANYWTIGYCHGINVIQFHENLDDFISGIHKPHSPNHVYTLGNFSKQTSPLEFEFDTKERTISQRLLGEVCDLTGEPRTIDTIYRCDHILEIVELTEIRTCQYELHINVPKLCSLPEFKRTNLEEGVSEILCTRIE
The following text describes a protein:
Function:
MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDVGTIIGIIAAFLLILISILIGGSITAFINVPSIFIVVGGGMAAAMGAFPLKDFIRGVLAIKKAFLWKPPDLNDVIETIGEIASKVRKEGILALEGDIELYYQKDPLLGDMIRMLVDGIDINDIKATAEMALAQLDEKMSTEVAVWEKLADLFPAFGMIGTLIGLIQMLRNLNDPSALGPGMAVALITTLYGAILANAFAIPVANKLKKAKDMEVLVKTIYIEAIEKIQKGENPNVVKQEAAIMLGVELPEEV
The following text describes a protein:
Function:
Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).
Sequence:
MAEFLDDQETRLCDNCKKEIPVFNFTIHEIHCQRNIGMCPICKEPFPKSDMETHMAAEHCQVTCKCNKKLEKRLLKKHEETECPLRLAVCQHCDLELSILKLKEHEDYCGARTELCGNCGRNVLVKDLKTHPEVCGREGEEKRNEVAIPPNAYDESWGQDGIWIASQLLRQIEALDPPMRLPQRPLRAFESDVFHDRTTNQRNITAQVSIQNNLFEEQERQERNRGQQPPKEGGEDGANLDFMLALSLQNEGQASSVAEQDFWRAVCEADQSHGGPSSLSDIKGAADETMLPCEFCEELYPEELLIDHQTSCNPSRALPSLNTGSSSPRGVEEHDVIFQNFLQQAASKQLDSLMGLSSSRLVEESIIIPCEFCGVQLEEEVLFHHQDQCDQRPATATNHVTEGIPRLDSQPQENSPELPRRRVRHQGDLSSGYLDDIKQETANGPTSCLPPSRPFNNMTATYNQLSRSTSGPRPGCQPSPPRVLKLNNSDSQDIQGRNQNSQNGAIAPGHISVIRPPQSLYPENIVPSFPHGPAGRYGASGRSEGGRNSRVTPAAANYRSRTAKAKPSKQQGAGDAEEEEEE
The following text describes a protein:
Function:
Plays an important role in the elongation step of protein synthesis.
Sequence:
MVNVNELACAYSALILADGGVDVSVRSFCSKKSSLNTPIAKSYRDNRNFRPELHIPRIESPLKLRLCSLLSPDHITKLLKAANVTVDSLWPTLFASALKTVNIKDLVKSAGSAAPAAPSVAATTAATTAAAPVEKKEEKEEKKEESDEDDGDMGFGLFD
The following text describes a protein:
Function:
DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription of non-classical heat-shock genes such as PDZD2 and PROM2. Protects cells against heat shock and proteotoxic stress.
Subcellular Localization:
[Isoform 1]: Cytoplasm. Nucleus. Note=Cytoplasmic under normal conditions. Translocates to the nucleus in response to heat shock; [Isoform 2]: Cytoplasm. Note=Does not translocate to the nucleus in response to heat shock.
Sequence:
MEQFRKTMVPHFLTKLWILVDDAVLDHVIRWGKDGHSFQIVNEETFAREVLPKYFKHNKITSFIRQLNMYGSRKVFALQTEKTSQENKISIEFQHPLFKRGEACLLANIKRKVPTIKIEGASLYSDEFQKIVTEMQEFKDMQRKMDAKYTQMKQDYSNLYHEVTNLRKKYCAQQQLLTRVLHFILDLMSENHTVLKKRKRSLSFISEDSDSEWDHQYFRIPEDKKEAMEILKDGYELVEDKYKSLLDRVMPILKESKKLISSGDQPSGDDGEHPKVPVQDKPMNEESLTIQLDLTIPVLPEQITEESVEQEPKDISLELDLSSQDSILMKDKSDNLYNNIINRDKKDMHHTEGNLLELNSLLSRKALNYDSDHFSESLSLMKNEEEKSQLDLSGGKDNHMIQCMETPELFLLDEIPMCDFGENLQDYDRLLEDLKNPPNVISALCDHDYVTSNISTLQEDTIENSIPQLCMEANGESSVFPFLILNPVTNIF
The following text describes a protein:
Function:
Forms a fork protection complex (FPC) with CSM3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MEEVDRLVTASITSIVSALGGCDLASEDASYVLGEEALACLKDVKQWLRAFDEKLGRSDVAKCIASTTLVVSDIPSILSTWNTQSEAGQASKKMDRVALACLEILVPLLWPIEINDETPDNVVASADLLRQAQIRYKRALLGHPSKSILKAVVRLCIPSVAKSKADRDQRDIGIMKLVVFFIRNMLAIDPMEANGKTDDINRSAILEAFENQGVLDLMLTLGSCTGYDIVGVDLPLLDSLYQMVKGLDVVEIFETSPNEPDNQLKNLLDTERRNKPVGSSRHSRFASTMTVLHNGSKISVTGPTASIEKSLEKFDKSKQPGRRLTKPTTGVWEVPVFVGHSAKRYIRVFSELFNDSAFNPLMQTVRKALEQEDDIGPAFKHYLVVLKWFLGVEMHRKTPDFGLIASVVNQEAFIIIMRSIRQGVQAKNWTMVKTAMDSFKTTLVVVNLMSDEEVASNIKARLFYEEEYLTMLADLTRRWALPLTFLQSAVDMTHTLIKTLESFTKANTTLYVRRRRLRAQKKADDTGNVEDLESLPGEEHESAIESRERKFNFSSFESRYFHEDTFTTYRMVLSSFQQLDNCYLGWCLKFLDRAFNKRKCRVMLFRLDYLQLFRTMVKELNSSNPWRKPFEHFFKKYMRQMIPMMKERPCLMVEVIFAKIPGTLHYLESGEEKPVRELKERTSKFVYEFTEGDDIPEERKVCILVASLLDEEKKQLVEWFIDELDSLLRARTGDTQVLNPPKATDELNVPKSIDEDDKFRLLMELVGFTLSRIPKSSVGCKTLCSLPGEVSRADIERATGWLKQWYSTPVDFEPFNKIKRVRRDDKERRGAGGDKEGSQDAEEDDELPLFLASDSEDDIENINDEMFAPVPKEKQQKTKQKLKRKGTSKSTREREKQRDYTAKTTIDIPMSYKSADFIGASDDDSDDERDRKFFEKENELREELRKAEPTINLEEKVDKAFKRQYAYVSDGEEEPLSETESHKQYREKVDEDRDDLSHMAERENRQYDFGDEGHDSDNLEIIDDDSKSPVAAEGTTSSQPIRKRRIVDDSDDDE
The following text describes a protein:
Function:
Resistance protein interactor which positively enhances RPM1-mediated resistance to necrotrophic bacterial pathogens Pseudomonas syringae pv. tomato DC3000 harboring type III effector protein AvrRpm1 or AvrB, but prevents the hypersensitive response (HR) controlled by RPM1. Together with ARF1, promotes leaf senescence and cell death, probably by facilitating the translocation of ARF1 into the nucleus, and activates ROS-related enzymes (e.g. POD, CAT and SOD).
Subcellular Localization:
Nucleus.
Sequence:
MGSGNHVDIVDVSSGEEDVDTRGDVEYTDWLNGVMEPVDDTSDSTDIVEVLSEVRGGVNSQYRKPNSSNQALEDDDDCVILDCDPDKTRETTSVDDDDDDDVLVVGQKGEIACRDFPHPRHSCAKYAFNSTSHEKYCDMCHCYVCDIRAPCPYWCIAVSSIDHCHANDKEKIWKNQREYFRTGYMPTAPSSKPTPSILRVPKNTLLRKNHVEIRPCSSSTRVANPSSVKARHRIRQPIPHNQGLQSQPAQSLSTVRDSVIQKDRSSYRFSLRSRVASSAGNGISIRFNNAQVSQSSHHSSSTVAPTLNPETYTQQRNVRDHCTALPGSQSNVFTRHADQNIRGSGNRQFQTNVDRFAPSKAPLTAEDSHTATVQQQPGINENVLETKLSEFEKWLMENPNPTGPVSPLPEPGNQDYASTLSFDFETFLND
The following text describes a protein:
Function:
Displays a modest preference for threonine over serine residues. Does not phosphorylate myosin II, however can phosphorylate MBP, in vitro. May be involved in the regulation of myosin II function during cytokinesis. Overexpression leads to impaired cell proliferation in suspension culture and fails to develop beyond the mound stage. Both overexpression and absence of the gene can result in defects in cytokinesis and alterations in myosin II abundance and assembly.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm, perinuclear region. Contractile vacuole membrane. Note=Enriched adjacent to large spherical structures such as contractile vacuoles and Golgi-like structures (perinuclear).
Sequence:
MESKYVLSTEKESKTKPSGRVNVSDMDSISNSLSKTSLGTRKVPTSLKTDASRSGLSSGGSKTHISDESALRMVYGSTPRDEKTTTTKDSITLAKEKEKKIEKRNEEIKLTFKAIRASECVDLLFIVDCTGSMDPYIEQIKSDIVKLQEALKLKHSFLDIEFGFIRYTDFDVASNRCSTFQFSRSTVEFVRFVSEIRAGGGADGPEDVFGGMDLIKSMKWRPNSTRVVIHIADAPCHGTEYHSMADSYPGGDPNGIKLDDLLTDIISLNINYYFGHINLKETGQMIDFFDKKTKEISRNKKSINSFDSKETSKMNERIFISIEESISVSRSVLTEQYLGHNIDGSTGKQRSEREFEINTNMDIDFGELPYIQMLQTKFKMPSDIVTCLSSSYEMKLNEITISIKIAPNPFSHGACRLAYLGIDEHGKKVVLKQSKYIGGRENSKKRYFESMECQTVAAKFALEFNKQLSLTSSEHQITFTVAKVLQMKHSEKPMYFGIETFINGEYQKYNSNCGWLKDDAMSEILQTFSHWTYQESKNKAIVVDIQGVKTSKGYLLTDPAIHSTDTLRFGSCNLGKPGIIKFFQSHKCNQHCKKLGLTIPSFTSSSSTSSSSRSTSSSSSISYSY