lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in zinc transport from the cytoplasm to either intracellular organelles or extracellular spaces.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MENFKNNELESSPIINKNNSSHSINNEDNNYYSHNLEHNDNNNNDNNNTITNSHINNHDHKHNHEHEHKHKHNHDHNHDHDHNHEEEYGHGNELEHNNDQEHNVGNKNLLTNNNNQSKKKKHGHSHGGGEDGSSSGGGGGRHGHGHSHGGGSGSDHNHGSSDEDDEESKPLNQLRNLDSKKKARYSLILALTLTTIFMVGEIVGGYFANSLAIMTDAAHLLTDIGAMFLSLFAMWISQHPPTSSMSFGFHRAEILGALVSVLMIWALTGVLVYEAIQRILYPPDAVDGKIMFIIASCGLFINIIDAIILHWGSGGHGHSHGGGHGHSHGIGGGTQKKKSKKNRLLNNQGQDIEDLGGENGKNKKGVRNINVHSAYIHVLGDCFQSIGVMVASCIIWVHPHWKIADPITTLIFSVIVLGTTIKLLRESLGVLMEGVPPEIDVSEVKGDLSEIEGVTEVHDLHIWSITLGRPALSVHLTILPTIDPEEILSIANKILLEDYEINHTTIQIEKPLVKDKCKDHSCPPPKPKKKKIKNDNLSSPPNQ
The following text describes a protein:
Function:
Specific regulator of miRNA biogenesis. Binds, via the C3H1-type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA.
Subcellular Localization:
Nucleus.
Sequence:
MSDKNKDDDICRDFLRNVCRRGKRCKYRHPDEGEGAGGQQKQSYAFCHDYQNKGCDRNNCKFIHCTREEEDFYKQTGELPSSLQKQTGVGSGGVGAGMLGLGASNGGGSLGGGDIPIGRDFLKNECHRGSKCKLRHMAQDEYDYPLSSRDSLAPEPPLPSYTSRYDSYEPRYDDYEYDRLRLKRRRDDLDFDYRERERDYEPPRPRPLDYRFLEDENIMLRRKIDELKKQVSDLQATNEVLLEQNARYRTERALQRSGTPPRSENLPVTNYNHGIISQAITHTISHASVTNPQIPQAPSVTQLNSASLNQAQSRGLAQDLLSGPNAAAASAAAIPISHQGSTLPVSVAQAIASVAQQGLVSYPIMTGNMRTAMAQSSLSQSLPQH
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE).
Subcellular Localization:
Nucleus.
Domain:
The hydrophobic-rich region (HR-A/B) corresponds to the oligomerization domain.
Sequence:
MAAAAGGGAAPFVWKTYRMVEDPGTDGVIGWGKGNNSFVVADPFVFSQTLLPAHFKHNNFSSFVRQLNTYGFRKVDPDRWEFAHASFLRGQTHLLRNIVRRGSAAAGGGGGGGGGKRRDASADGGGGGGDEDMTMVATEVVRLKQEQRTIDDRVAAMWRRVQETERRPKQMLAFLLKVVGDRDKLHRLVGGGGNGNGAATAAAADNGFADAARAGCGEKRARLLLDGDNTGAFGPDAVDFAGFYTGADMFPDVAVDAAAAAAGGSAGCSFAFGVDSGY
The following text describes a protein:
Function:
Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between nucleus and cytoplasm. Nuclear export is XPO1-dependent.
Sequence:
MGKIDVDKILFFNQEIRLWQLIMATPEENSNPHDRATPQLPAQLQELEHRVARRRLSQARHRATLAALFNNLRKTVYSQSDLIASKWQVLNKAKSHIPELEQTLDNLLKLKASFNLEDGHASSLEEVKKEYASMYSGNDSFPQNGSSPWYLNFYKQTMDLLTGSGIITPQEAALPIVSAAISHLWQNLSEERKASLRQAWAQKHRGPATLAEACREPACAEGSVKDSGVDSQGASCSLVSTPEEILFEDAFDVASFLDKSEVPSTSSSSSVLASCNPENPEEKFQLYMQIINFFKGLSCANTQVKQEASFPVDEEMIMLQCTETFDDEDL
The following text describes a protein:
Function:
Metalloprotease.
Subcellular Localization:
Secreted.
Sequence:
MRFLALLPLFFALGLCGVLPHTKFEKEIEKQIDVDEFKKDMKILDAHLAVETDAERAELQNLLAAVEPVPSLEAEAEKDEEAVNADNKADLFEGDIVLTNEQLSYVMANETERAKRQASMNTAIWGTTPIPFSFAAGVSDEVKGIVRAATAFWTANTCVNFQENGAGENKILVVNKGGCYSSVGKVGKTQELSLQNNGCNSISTATHELEHALGVYHEQSRADRDTYVRVNKDNIPTQNQHNFDSYPTSSAMGLPYDFGSNMHYTSDSFAKDYKIPTLIAVGSYADYQNSMRGHMPSFLDILKVNKYYKCDQKCSNKANPCKNGGYLDVRNCAKCVCPEGLGGPDCTGNPDGCVVELQASTSYTKRTIEMGKYGQPAQLKYENCAYVAPEGKRIEVVFDAIYSGYGSGCRMGGIELKTKTNMLQRGFRFCETPTKKSYWSDTNKLPMLVWSNEGSFRADIHLNKMVRAFRCKLFSFLTIHSIKCTFA
The following text describes a protein:
Function:
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Subcellular Localization:
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Sequence:
MASPTNAPGSQSQTSVSSANHPDPIIHGREILETLVSHLLASKRSLSSISTVWRANEIVTSAKTALEESVILNARTGFLQSGINEQMKVLMKVRNSIECVYNDGQKDFKNVLHTLDAANARLESTMDVLRSTMVDAAFRPAGEEPRSLLDFVDEQGVEGMRDGLKELIRESKETQKEFDTSLLSFDDDLRSLRSGFKNTKVSPPSYSPIPSHLATLEGHAQEMAALLSSLSSHFDLCLNAIRHTEGGYAAVRNAASNPPPGAEPVSVSGVMNTSHDDINEEPLTEHEREEMLFVLEKDAAEVEDVVMELRDRQNEMEIKHDAILDHVSHLTEQFKQTTSIYKILEGVYERLPGYIIAGQDFRARWEDTKAQICGQMDDLEGMRLFYENYLSSYDGLILEVRRRKVAEEKAKTIAKKAMEQISKIYDADMKERHDFKHDVGDYLPVDLYPGINAAAPRWEFRLMEDEEAVNSSPSLERELVEVSSKRDGEAQG
The following text describes a protein:
Function:
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
Sequence:
MNKAQLIQRIATSLEQSQASTKPVVEQILQQIHIALSEGEKVFLPLFGTFELRYHLPKSGRNPQTGEAIEIAGFNQPSFKAATALKQAINE
The following text describes a protein:
Function:
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in mitochondrial distribution and morphology.
Miscellaneous:
MISCELLANEOUS: Present with 2250 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MHWAAAVAIFFIVVTKFLQYTNKYHEKWISKFAPGNELSKKYLAKVKERHELKEFNNSISAQDNYAKWTKNNRKLDSLDKEINNLKDEIQSENKAFQAHLHKLRLLALTVPFFVFKIMYGKTPVYKLSSSTSTLFPTFVSGVWSQGWLYVLLHPLRTISQKWHIMEGKFGASKFDDMALQSVSLGIWVWALMNVINGVEFIVKQLFLTPKMEAPASVETQEEKALDAVDDAIILD
The following text describes a protein:
Function:
Involved in de novo DNA methylation. Involved in RNA-directed DNA methylation (RdDM).
Subcellular Localization:
Nucleus.
Sequence:
MRIASSSGILMDANGKANGSAPSALVAYFLGMGFSREMVFRAIKEIGDTDSEQILELLLTYQAIGSDPSVGNSSHSACDPQILEEEDEEEDVNWDEDDTVDNFDRATYSDGSGDEDFLQEMSEKDEKIKSLVSMGFPEDEDTEFSSFGGRKKTKLIDGSKKKRERYRSRPQWNQVPFDGSHEEPMPLPNSMVGFSLPNDGLRSVHRNLPDQALGPPFFYYENVALAPKGVWTTISRFLYDIYPEFVYSKYFCAAARKRGYIHNLPIKNRNYTRGVSRTARYRALGNSFQVDTVAYHLSVLRDIFPNGMNVLSLFSGIGGAEVALHRLGICMKTVVLVEISEVNMTLLRSWWDQTQTGTLIEIADVQNLTAERIELFIRRFGGFDLVIGGSPCNNLAGSNRYHRDGLEGKHSALFYHYYRILDSVKTIMASIFGAKGKLFRHVRKALLLKQSSSLTLKTEQDPSNNSDKDSMDK
The following text describes a protein:
Function:
May have a role in autophagy.
Subcellular Localization:
Lysosome membrane. Late endosome membrane.
Sequence:
MSVEIVPLPLRINENESFLSYDDRLNRVVFKTSSGFGVVLLDDPEANRRYYSSDKPIIDAKFSPDLKYSAIQFSDYDIEILHLENGTRYIQTCKYKSSKATILGYYWTTKENILLVTNASLELYAMGLDGSCKLVKESKIKITNCVYSFNCNFGVLFLHSGGTSIQPYFFRTNSFDKLPKFNIEGNGNGFNIKNLYVTKLHEKFFCVYGDQEYIYLYEMTLETIYKIKPIKILLSGPNSIHFVDNLIIVHSELNISIVYDLKTIQRDRERGQTNKKEPEFPISAIPMTLSTINSNNLLYLMNNATKTHSTTSTPIINSINNNNNNNNNPSSSSSPSSSNNSQSSSPTMISSYEQRQIDQHKEQQLQKPNVTLYSKNWRFICPNYIFDPDSGIWYEVTLNFEKISNFLQFDSHKTIPFLQERTLLSAKFALLSIIKTIIEFKTDTLDGIGKIYDDLNKVLFRTTNRQLTESLHKSINQPNNNNNNNNNNNNNNNNNTAQTLNSTGNLSNSISIGGMNTSTDNLTTTTTTSSSISSSPSNSFIGNSKTNVNNLSYLNYKKQQQQQMEKQQHMPNDDEDSFSLIGDGGSGGSGGSFYNTNTNTTSTTNTTTSPSGKSNSNLKLSQSLNNTPNQSPNSRSSLNNSSNNINNNNNNNNNNNNNNNNNNHVVQNRQSRSNQYILINSHDMYDFVFNPIYEKLLIESQKEKEKENDNNNNNTNNNTNNNNNNNIEELNSNEKLELDSKYLIAVVIQYIKSLSFNHCTGISDKLYNLLISLLIDNNMFSRLHQFLQYYVITDSLSIAYKLLSIGEQYPPVLQLSLDMFKRLSMPNIIIETLLERGQVIQAIRLLRSTKETNEQAYQELLTPTYPIQFLASSSNQSNDTLFFSVFKFFETNNLIIPSHPSFDKYIKLFIEKFTEKSLSPLLLDILSNLNNNSTSGGDITPKKNVGGSFLNQSLNNSSPTLRSSNSLNSSPRLQYSNN
The following text describes a protein:
Function:
Essential for the embryonic synthesis of chitin, a component of the eggshell.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=egg-1, egg-2 and egg-3 maintain the homogenous distribution of chs-1 at the unfertilized oocyte cell membrane, thus ensuring the formation of a continuous and cohesive eggshell chitin layer. In the fertilized embryo, co-localizes with egg-3 to cytoplasmic foci in an egg-3-dependent manner.
Sequence:
MNDGENYWNAFRSHKRSATDGPTLSPWMVTVLQATKLLLFALCNIVLTLGSVFSKLIVLIMATNIVPRAHLIGKFARKCTKAAVRRTSTTTAGIYLSLLLIQCFPDTINLIRSGIDMWKGQCGQLVKSVVVLESLRAIGLAVLSFHVFPQLDLARCLVLSACFPLVAVLQRSLVAMVSAARTGRSFRNRLGRCFVAIPHVIMFLVLMSSCYVWALFDNKFTAIIALPIGVICTSAGFWESWIDTTHSGTSFDELYRLKYAVRKMNTTTKLIVSLMRIVCTVSVLVSAVYINDHKKLNSSHFVKAFFSFSTRQPHTRLLLLATGIIVLHFVMRGISRFLAALDLHPFSFVHPLSIAPLIAYGYVRYACQSPTCSIARRLARFGLHWVCDQWFQSARGIASPDFYICLIWLLVGCYRGWRLVRQRYFDTNEEIISSMPPVCNGLCIEQSLVVFQHSLNRQEKTMLTEEEDISDENDELRIRNDEVDRVSTVYGCATMWHETETEMRQVLRSILKLDVDHATRMNNKKANELRYRLEGHIFFDDAWEDVEEDGIEKRQPNEYFNMFFDLLNEMTGERLNEEGKMETRILVNTPYGGRLVVKLPSGTLLFVHLKDKKMIRHKKRWSQVMYMYYLLGHRIMDCPLSIEDRQQMADNTFILAIDGDSKFEPDALLRLLHLMNAKSDIGCACGRIHPIGNGIMVWYQKFEYAIAHWFQKAAEHVFGCVLCAPGCFSLFRASALMDDNIMHKYTKTASEPRHYVQYDQGEDRWLSTLLLKQGYRIEYAAASDAETYAPEGFEEFFNQRRRWTPSSIANTVDLLMDYKRASENNDAISYAYIAYQFLVIFFSMLGPAIIFTMLVFAQVAAFELRGSDVMLYNGIPIGFFIVLCFTTESNIQLIYAKYMSIAYAFVMLAVLVATSSQIVLETVLAPTSLFIVTMVGIFFFAACLHPKEFTNIIHGVVFFLMIPSTYVFLTLYSLINLNVITWGTREAVAKATGQKTKKAPMEQFIDRVIDIVKKGFRLISCREKKEHEERREKMEKKMQRMELALRSIESGADVKKILDATEEKEKREEETQTADFPIEENVEKTQKEIQKANRYVWMTSHSLKVCERGKLKSAEKVFWNELINAYLKPIKTTPAEMKAVAEGLASLRNQIAFTILLVNSLLALAIFLIQKHKNVLSIKFSPIKNFRWTKMNEMTGQYEETDEPLKIDPLGMGIVVFLLIILFVQTLGMLLHRLNTMIGAFQEVKNLYEYGVSPVINTKNDDERIMNNARLMINSLGVSTGHAADGYTRHRGEESDTGNVLYKLQKARLAKRMQRSALSTTE
The following text describes a protein:
Function:
Required for heat stress-instigated phosphorylation of BCY1 which is involved in cell wall integrity signaling. Regulates activity of MSN2, a transcription factor that binds to the stress-response element (STRE). Probably promotes formation of a complex between MSN2 and DNA. Regulates the stability of ROG1.
Sequence:
MLKVNNVFGSNPNRMTKLEDEHYFIDDIVSIKNRQKSKMYVREGKRIGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSIKNSQELQDSLNDQKFKKFMHWFPSIEFFDVEFLLKVLTYDATERCDARQLMAHEFFDALRNETYFLPRGSSMPVHLPDLFNFSASEKRALGEYYNLIVPSLD
The following text describes a protein:
Function:
Part of the ABC transporter complex involved in maltodextrin import. Binds maltodextrin. Can also bind maltose with low affinity, but is not involved in its uptake.
Miscellaneous:
MISCELLANEOUS: Maltodextrin can also be transported inside the cell after degradation to maltose by extracellular amylase AmyE, transported as maltose by MalP.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MVLLKKGFAILAASFLAIGLAACSSSKNPASSDGKKVLTVSVEETYKEYIESIKTKFEKENDVTVKIVEKQMFEQLEALPLDGPAGNAPDVMLAAYDRIGGLGQQGHLLDIKPSNTKSFGDKEMQQVTVDGKVYGMPLVIETLILYYNKDLLKTAPKTFKDLEKLTEDPRFAFASEKGKSTGFLAKWTDFYMSYGLLAGYGGYVFGKNGTDSGDIGLNNKGAVEAVKYAEKWFETYWPKGMQDNSSADDFIQQMFLEGKAAAIIGGPWSAANYKEAKLNYGAAPIPTLPNGEEYAPFAGGKGWVASKYTKEPELAEKWLEYAANDANAYAFYEDTNEVPANTAARKKADEQKNELTSAVIKQYETATPTPNIPEMAEVWTGAESLIFDAASGKKSTQTSANDAVNVIKENIKEKYVK
The following text describes a protein:
Function:
Catalytic subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase. Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
Subcellular Localization:
Cytoplasm.
Sequence:
MAVTSQANAQEVAAVKKDAVRDKSVYSPVQLSRIDHTPTLPAVLQGNFKLNHGPPTTAAGQPEEIQKLFPCLYGQPSVQLVESDAPTYNVDQKLKVGVVLSGGQAPGGHNVIAGFFDYLQTHAPGSVLYGFKGGPAGIMRNNVVEITADFLYPYRNQGGFDIICSGRDKIESPEQFQQAVDTVTKLDLDGLVVIGGDDSNTNAALLGEHFRAKKVRTHVIGCPKTIDGDLKSPEVPISFGFDTACKIYAEMIGNIMEVNAQKKTLRQVTNSIADIVCKRAVAGKQYGVVLIPEGLIDFIPEIQHLISELNDILASQGCDDHGHWKATLKPSSRALFDSLPHSIQEELLLERDPHGNVQVSRIEMEKMLISMIETELNARRHEGGYSGQFKGQAHFFGYEGRCGMPTNFDATYCYALGFAAGALMHLGQTGLIASVANLTAPAAEWTVGGTALTQLMDVERRKGRNKPVIKKAMVELGGAPFKKFASVRDVWAVEDSYVSPGPIQFAGPTADETNFTLKLELGASVNL
The following text describes a protein:
Function:
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Subcellular Localization:
Nucleus.
Sequence:
MFHPSAAELRRLMMLHGGQFHLYYSRSKTTHIIATNLPNFKIQELKGEKVVRPEWIIDSIKAGRQLSYIQYQLYAKQKGLNFTRVSGIEGQDPSSNHGPDIKPQPSHTLSKDVLKSTQANHMANYTEKTDHQLDIRLRNGLHSIISEVDAEKSRVNGIHDDDDDDDIACSILPRGSQDTLLTNGHVHPVNGALKPQDFADHHPHVVDKASNQSHLPQDKYREGEEPCCSYTESKANSHLRSLISAASPAKQPGPHNMQTDLHQKPTSNSGTLGAPQKASLHDQTTVRLNGSYHVTSNSSTLANSSNQSGKSSAEAGIISEFFSHSRLHHISTWRNEFSEYVNSLQSRRRAAGGAVFSGREKLKKLKANCNSGSLMAAPQVRQSCVLHVDMDCFFVSVGIRHRPDLIGKPVAVTSNRGPGRVAQRPGANPQLEFQYYQNKQKHYRKEKTDGDLEMTPSPQDGEVPSNGVHEDLAALSMAEIASCSYEARQAGVRNGMFFGRAKQLCPDLQSVPYDFHAYKEVALAMYEILASYTHNIEALSCDEALVDATALLVELGVSPDELARSIREDIKEKTGCCASVGMSSNILLARMATRKAKPKGQYLLRSEEVDDFIRDQPVSSLPGVGRSMSSKLTSLGVSTCGDLQQLSLSQLQREFGPRTGQTLFRFCRGLDDRPVRSEKERKSVSAEMNYNIRFTQVEEAESFLNNLSMEVQKRLEGAGLRGRRVTLKVMMRKPGAPVEPAKYGGHGICDNFARSVLLAQPTDSGRVIASEAIKLFHAMKLNVKDMRGVGLQVQQLDGSHADPSGQGPSRGRSIRDLLLAKQSAHSPSKESPSQDGLISASSSRAFSSNQKRVTPALSPPPSTSSSSSPPPSFTIIDPMPGTSKGDYHHPHTPNHVRACLNISIEVPSPSQVDPSVLKALPIDIRRQVEETWRYREEQPSTSSHYSTPPRPPSTPPPGPSLVLQLPNQPGQPCTTGIILELPDFSQVDPDVFAALPRELQEELCSAYRNKGNAQAQASTVVEQKNSFPQLKQPAVGKLKRRYKKRNTSPAKNGSSPLKKMFPGNSPAKTSPSKTLPLPLREQDLKCPSSLSTDVPETLPKPIPRPAPTLAGAHEFSEIRTLLREWVTTISEPMEEDILQVVKYCTELVEDKDLEKLYLVIKYMKRLMQQSSESVWSMAFDFVLDNVQVVVQQTYGSTLKIT
The following text describes a protein:
Function:
Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis.
Sequence:
MSSLNRELSTDSAFAAGRNSWNRHYHNSVVQPLLTDLYQITMAYAYWKSGKIDDHAVFDLFFRTNPFQGEFTIFAGLEECLKFLDSFHYSETDIEYLKHALPQGIEDEFFEYLSQLTAKDVTLYAIEEGSVAFPRVPLIKVAGPLIIVQLLETTLLTLVNYASLMATNAARYRMVAGKHIHLLEFGLRRAQGPDGGLSASKYSYIGGFDGTSNVLAGKLFNIPVKGTHAHAYITSFTGIDELKTRLLQHKEDGTTRDLLELAMEHRAAIASVLDVSTDESSEGELAAMVSFAIAFPDGFMALVDTYDVKSDKALGEPTEELSDPPDSVVCDSLCAGRLLDQDADAGSLLPVGCTALPEIPEEECNGCCAEEHGETPCTLHDDVDGEPSSAGDDQEQQAEEEATEPDAAEESCPPPSITVEDEDEVPVGEGEPGKGGSDENGNEDIEDQNVRNATEQEQEEQGEGDEAHQNQVVVPEEEIEEQKEEDDGGGDGGGGGGGEDEIIRCANCEALNTMIHHLKSVGKSFSRTCWLERSLAEFSRVAAHHIELLSYYDLTRHHHSLSRSGLLNFCAVALGLNDQGYRAIGIRIDSGDLAYLSCLARETFERIAERFKLPWFSKLTIVASNDINEDTILSLNEQGHKIDCFGIGTHLVTCQRQPALGCVYKMVEINNQPRIKLSQDVGKVTMPGSKNVFRLYGADGHALIDLLQRVDENPPEVGQKVLCRHPFQESKRAYVIPTQVEPLYRVYWAEGRVAQVLPSLEEVRERVQASLRTLRQDHKRTLNPTPYKVAVSDNLYNFIHELWLQNAPIGELS
The following text describes a protein:
Function:
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
Sequence:
MKKNIQCLNIFYKTKWRNIHNSSIVRSKENLNLQKIYTGEKQNFNKVSFKKEKIEDVIKEVKFDYYYFNEGKKNKYKDIPLNISIINESDFPPFKAVDEKLHFSVLENDLKIISTNRNNSVCSIGLYVKCGSRYEEINDKVNEQGMSVMLENMAFHSTAHLSHLRTIKSLEKIGATVSCNAFREHMVYSCECLKEYLPIVTNLIIGNVLFPRFLSWEMKNNVNRLNLMREKLFENNELYITELLHNTAWYNNTLGNKLYVYESSIENYTSENLRNFMLKHFSPKNMTLIGVNVEHDELTKWTSRAFQDYVPIPYTNQKEVTPKYTGGFISVEDKNVKKTNIAIAYETQGGWKSSDMITLTVLQTLMGGGGSFSTGGPGKGMYSRLFLNVLNSYNFIESCMAFSTQHSDTGLFGLYFTGEPSNTSDIIKAMALEFQKMNRVTDEELNRAKKSLKSFMWMSLEYKSILMEDLARQMMILNRILTGKQLSDAIDSITKEDIQRVVHNFLKTKPTVVVYGNINYSPHYDEICNILGHK
The following text describes a protein:
Function:
In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
Subcellular Localization:
Nucleus.
Sequence:
MSFGSPKNGEFIECTDPAIREYLIFLNSKEPAEHKFIITDIDDRYLFIKAGVSDKLKEKINLLVTSNTFSEEDRDSKKKKQRVI
The following text describes a protein:
Function:
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
Subcellular Localization:
Secreted.
Sequence:
RIFQICELSRVLKENGLGGFHGVSLEEWLCVIFHESGYDSQALNYYNGSSSHGLFQINQPYWCDDXDSESTEPSVNACQIPCSKLLDDDILDDIECAKKIVKEPKGITAWEAWQPFCNSDLDQWKC
The following text describes a protein:
Function:
Binds the poly(A) tail of mRNA.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAQNHENVNNDVAAAPVPNQLTTTSLYVGDLDHDVTDSQLYDLFNQIGQVVSVRICRDLASQQSLGYGYVNFSNPHDAAKAMDVLNFTPLNNKPIRIMYSHRDPSVRKSGAANIFIKNLDRAIDHKALYDTFSIFGNILSCKIAMDASGLSKGYGFVQFENEESAQSAIDKLNGMLLNDKPVYVGHFQRKQDRDNALSNAKFNNVYVKNLSESVTDDDLKNTFGEYGTITSAVVMRDVDGKSKCFGFVNFENADAAAEAVEALNGKKFDDKEWYVGKALKKYERELELKERHEQSMKETVDKFYGANLYLKNLDDSVTDEKLSELFSEFGTVTSCKILRDPQGISRGSGFVAFSTPEEATRALAEMNGKMVAGKPLYVAPAQKKEERKARLQAQFSQVRPVTMAPIAPRLPFYPAGVPGMGQQIMYGQAPPAFISQAGFGYPQQLVPGMRPGGAPMPNFFMPMVQQGQQGQRPGGRRGASPMQQLPHSLPMMQQQMHPRGRVYRYPTGRNPQGIPMPGVAGGTPMQALATALANAPPEQQRTMLGEVLYPLVEKIEHAGAAKVTGMLLEMDQPEVLHLIESPEALKTKVAEAVDVLRNVAQQQSNSPTDQLASLSLNDNLES
The following text describes a protein:
Function:
Guanine nucleotide exchange factor (GEF) regulating homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion, possibly through activating Rab proteins such as RAB27A and RAB27B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB27A and RAB27B into their active GTP-bound form.
Subcellular Localization:
Late endosome.
Sequence:
MAAAEVADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITTIEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLNADELEALQMCTGYVAGFVDLEVSNRPDLYDVFVNLAESEITIAPLAKEAMAMGKLHKEMGQLIVQSAEDPEKSESHVIQDIALKTREIFTNLAPFSEVSADGEKRVLNLEALKQKRFPPATENFLYHLAAAEQMLKI
The following text describes a protein:
Function:
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
Sequence:
MTTRDLTAAQFNETIQSSDMVLVDYWASWCGPCRAFAPTFAESSEKHPDVVHAKVDTEAERELAAAAQIRSIPTIMAFKNGKLLFNQAGALPPAALESLVQQLKAYEVEAGEATTQNGRAQQA
The following text describes a protein:
Function:
May be involved in cell wall organization and biogenesis.
Miscellaneous:
MISCELLANEOUS: Present with 799 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MPFITSRPVAKNSSHSLSETDLNQSKGQPFQPSPTKKLGSMQQRRRSSTIRHALSSLLGGANVHSPAVLNNTTKGGNNNGNIRSSNTDAQLLGKKQNKQPPPNARRHSTTAIQGSISDSATTTPRSSTSDTNRRTSGRLSVDQEPRISGGRYSQIEEDSTVLDFDDDHNSSAVVSSDLSSTSLTRLANSKKFNEQFLIEYLTARGLLGPKTVLSNEYLKISISTSGESVFLPTISSNDDEYLSRLNGLNDGTDDAEADFFMDGIDQQEGNTPSLATTAAATESGGSINENRDTLLRENNSGDHPGSGSELNTRSVEIDSSMVSYSIAVIVSVKKPTRFTDMQLELCSRVKVFWNTGVPPTKTFNEEFYNAASMKWNLNDENFDLFVPLSISPDDQMIENNSNDRQMRLFKNIPTEERLYLDKTKTKASLLNAIDVNKTHLYQPGDYVFLVPVVFSNHIPETIYLPSARVSYRLRLATKAINRKGFYRQDSNSPQPIVSPDSSSSLSSTTSSLKLTETESAQAHRRISNTLFSKVKNHLHMSSHQLKNEESGEEDIFAEYPIKVIRTPPPVAVSTANKPIYINRVWTDSLSYEISFAQKYVSLNSEVPIKIKLAPICKNVCVKRIHVSITERVTFVSKGYEYEYDQTDPVAKDPYNPYYLDFASKRRKERSVSLFEIRTKEKGTRALREEIVENSFNDNLLSYSPFDDDSDSKGNPKERLGITEPIIIETKLKFPKYEDLDKRTAKIIPPYGIDAYTSIPNPEHAVANGPSHRRPSVIGFLSGHKGSKSHEENEKPVYDPKFHQTIIKSNSGLPVKTHTRLNTPKRGLYLDSLHFSNVYCRHKLEIMLRISKPDPECPSKLRHYEVLIDTPIFLVSEQCNSGNMELPTYDMATMEGKGNQVPLSMNSDFFGNTCPPPPTFEEAISVPASPIVSPMGSPNIMASYDPDLLSIQQLNLSRTTSVSGPSGYSDDAGVPNVNRNSISNANAMNGSISNSAFVSGNSGQGVARARATSVNDRSRFNNLDKLLSTPSPVNRSHNSSPTNGLSQANGTVRIPNATTENSKDKQNEFFKKGYTLANVKDDEEQEGIVSSSSADSLLSHGNEPPRYDEIVPLMSDEE
The following text describes a protein:
Function:
Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Vacuole membrane.
Sequence:
MSSTTPTSQTVESKPAPAALQASSIDQPPAFSSATPTCDIANPLPKPALATPRESSASSNNLAHRPKRAVIADSEPDMLEKGQAGSSNEASSALSRTLSSSDPASSITARKRGVTRDASSGGEGLGGPFAGPPRRATMESRATTRRSFNDLFTPEHRLAKPPATLVSLKNLLFGSILNLLLVFIPISWALHFALDQSVTRNGIAVFVTSFLAIMPLATILSQATEELSLRVGETIGGLINASLGNAVELIVAIVSLFNCELIVTQTSLLGSILSNLLLVLGTCFFVGGLRVKEQVFLEAPAQLNTSLLMMAVISLVIPSAFHAVLGGIPDNTERGDILKFSRGVSVLLLLIYIGFLYFSLSSHKEFFEDDNEDEEEQPQMNMTAVIITLVIVTVLIGVTSEWLVTAIDVVTSSGAITRTWIGLILLPIASNATEHLAAVIFAWKNKIQMASSIAIGSSIQIALFVIPLLVIIAWIGDRPLTLLFDPFATILLFLTVLIVNFAIADNRSNYLEGFVLIMVYLIVALTVWFVPDDLADTLFSDAYCHNR
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSVLTPLLLRGLTGSARRLPVPRAKIHSLPPEEKLGIMELAVGLTSCFVTFLLPAGWILSHLETYRRPE
The following text describes a protein:
Function:
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MKIIKPQWISHSGLSIYSIDVHPDGTRLATGGGDAKIKIWSVAPISLSEVENDENTPKLLCSIENSHFQTVNSVKWSKDGKYLASSSDDKLCMIWGLSKSNYMKSSVENWVCVATLRAHSGDISEVSWSPDNKYLATCSFDKTIIIWETSKFAMVTKLEEHKGFVKGLTWDPLGRYLASQSEDKSLIVWRTSDWVIETVITEPFQHNGNSFFLRPSWTPDGQFIVATHGINNATHTGVLIQRTDWKLGLDLVGHKRAVVVSRCSPIIYKEFKFKDRNFCLILLGGQDSTISLWSSSSPRSLMVAHSLFDQSIQDISWCPDGLSFVVCSTDGTVGYISLSEEEIGGTPITAAEKQTFFRNYYGDSVQLDKDGNLIYGGGNIQSSAANSGSHAVLPENPDQLAMEESIGGSGNNSSNAQNLENNNSDLPTPTTTSNKEIQPTQVALQNQKQTIVNGKRRITPIFIGNSSQNITKPQPLAIPLHLQQQVSKTTSPSPSTTATPTISNDLNGTPFKGGVRDDIVMDVSPIQEKLMQRGRDKRKDDDDNIIDKKPVTTSDRDDHFISDSSSTPHHKKKKSHHHHHHKEKESQQKESQQKEQPENNFHNQIVSTSIPSGFSIALPIISNKISKKIITEPQQPLNQIMNRFSETNTTTNQPSPSPPIVVDVNIVETELHDETVEYFSMIRYLTYDTQLWEVKIPGRVTLVTGNKYWCAVTTQDSILHVFNKNGAVIMSNLVLRNQISFLESNKTTHLLAITCDGFVSVWNILKKKSVLSNRELPFIKNRENLTIKHAFVTEETGKPIVTFSNGDSFVFCKEVSEWVKITDRLGALSEFNSVDTSNTGILSTLQKMGNKLGNSGIGSISSGNNSNNANDNATLSNLLALTNSESQSNQQQLLSTLFLEKQLWLSQVLESPQEYHHWLLIYAKYLTNSGSILKLQDLCTDLLGPSSTLNILDDIDSNTSFNTSQFNSSSLFNNPLSSIIPSWEATILGHQKRNLLKEILPIMASNRNLQRLVGQFRESLNNFSKNIILSDPFENLK