lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Extracellular zinc metalloprotease.
Subcellular Localization:
Secreted.
Sequence:
MKNKKTLTKVALTTGLALTAVAPYGVGHAEETDQLQVQIQEESFRSGELTQPSQKAPENVVKDALKEKTEQALSQKQVNGEAGVDYKVLQKRGSYDGTTLVRMQQTYEGKEVYGHQLTAHVDNKGVIKSVSGDSAQNLKQEELKKPINLSKDEAKQYIYTKYGNDIKFISEPEVKEVIFVDENNGQAKNAYQVKFEAATPNYVSGTYLVNAQNGDMLKNMVQESNLKASDKLVGALKKSKQSSLTSLTGTGKDDLGINRSFGISKQSNGKYALADYTRGQGIETYDVNYRDITKEESYYPGTLATSTSATFNDPKAVSAHYLATKVFDFYKDKYKRNSFDNKGQKVVSVVHAWDSEETNDPKNWQNALSANNGSMLVYGDPIVKAYDVAGHEFTHAVTSSESNLEYYGESGAINEALSDIMGTSIEKYVNNGNFNWTMGEQTGSVFRDMENPASVPSSLGVPYPDDYSEFNDFNGWDQGGVHFNSSIINKVAYLIAKGGTHNGVTVKGIGEDKMFDIFYYANTDELNMTSNFKELRSACIRVATNKYGANTAEVQAVQKAFDAAKIK
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Sequence:
MGNQQSQPEFVLRAPTEFSEKFVRHLQESTETDTSRYMDMENYIQKRVQDELKQLQLRQKKAIDAIQEEEWKSNAKTIKDSQGSLDSNLLSAEFRSFQEKLEKQSSINDKELKIKLKEVESIRSDLLKCMSEHPDKSLICHPLAEKFAILASKLHNPKVGSV
The following text describes a protein:
Function:
Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components.
Subcellular Localization:
Cell surface. Cell outer membrane. Note=The C-terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface.
Domain:
The signal peptide, cleaved at the inner membrane, guides the autotransporter protein to the periplasmic space. Then, insertion of the C-terminal translocator domain in the outer membrane forms a hydrophilic pore for the translocation of the passenger domain to the bacterial cell surface.
Sequence:
MNKIYRIIWNSALNAWVVVSELTRNHTKRASATVKTAVLATLLFATVQASANNEEQEEDLYLDPVQRTVAVLIVNSDKEGTGEKEKVEENSDWAVYFNEKGVLTAREITLKAGDNLKIKQNGTNFTYSLKKDLTDLTSVGTEKLSFSANGNKVNITSDTKGLNFAKETAGTNGDTTVHLNGIGSTLTDTLLNTGATTNVTNDNVTDDEKKRAASVKDVLNAGWNIKGVKPGTTASDNVDFVRTYDTVEFLSADTKTTTVNVESKDNGKKTEVKIGAKTSVIKEKDGKLVTGKDKGENGSSTDEGEGLVTAKEVIDAVNKAGWRMKTTTANGQTGQADKFETVTSGTNVTFASGKGTTATVSKDDQGNITVMYDVNVGDALNVNQLQNSGWNLDSKAVAGSSGKVISGNVSPSKGKMDETVNINAGNNIEITRNGKNIDIATSMTPQFSSVSLGAGADAPTLSVDGDALNVGSKKDNKPVRITNVAPGVKEGDVTNVAQLKGVAQNLNNRIDNVDGNARAGIAQAIATAGLVQAYLPGKSMMAIGGGTYRGEAGYAIGYSSISDGGNWIIKGTASGNSRGHFGASASVGYQW
The following text describes a protein:
Function:
Involved in vesicular transport between an endosomal compartment and the Golgi apparatus.
Miscellaneous:
MISCELLANEOUS: Present with 2350 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Note=IMH1 is recruited to the Golgi apparatus by ARL1.
Domain:
The GRIP domain may serve as a Golgi targeting domain through its interaction with the ARL1 Golgi protein.
Sequence:
MFKQLSQIGKNLTDELAKGLADDMSPTPSEQQIEDDKSGLPKEIQAKLRKFEKYEQKYPLLLSAYKNEKLKSEKLEAVEKILAENTPISNIDDAVDTLPAFFQDLNNKNNLLNDEIKRLTKQNSEIPESASSETLKDKEEEFLKKEQNYKNDIDDLKKKMEALNIELDTVQKEKNDTVSGLREKIVALENILKEEREAKKQKEEVSISELKEELAIKNHSLEDSRMKITELEQNLSSKSTIMEEKSSELAELNITLKEKERKLSELEKKMKELPKAISHQNVGNNNRRKKNRNKGKKNKGGITTGDISEEETVDNSINTEEYDKLKENLQELQEKYKDCEDWKQKYEDIEAELKDAKELENSQLEKSAKELETLNTELIDTKKSLKEKNSELEEVRDMLRTVGNELVDAKDEIKESSSKQNEEVKTVKLELDDLRHKNATMIEAYEAKNTELRSKIELLSKKVEHLKNLCTEKEKEQTTSQNKVAKLNEEISQLTYEKSNITKELTSLRTSYKQKEKTVSYLEEQVKQFSEQKDVAEKSTEQLRKDHAKISNRLDLLKKENETLHNDIAKNSNSYEEYLKENGKLSERLNILQEKYNTLQNVKSNSNEHIDSIKRQCEELNVKLKESTKKILSLEDELNEYANIVQDKTREANTLRRLVSDSQTDDSSKQKELENKLAYLTDEKNKLEAELDLQTSRKATELQEWKHTVTELKSEIHALKLREEGLKSEVDALKHVNNDIKRKTQATSDDSDQLEQITSNLKLSLSKADEKNFELQSANEKLLNLNNELNKKFDRLLKNYRSLSSQLNALKERQYSDKSGRVSRSGSIGTLANANIDSSPANNSNPTKLEKIRSSSSLELDSEKNEKIAYIKNVLLGFLEHKEQRNQLLPVISMLLQLDSTDEKRLVMSLK
The following text describes a protein:
Function:
Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
Subcellular Localization:
Cytoplasm.
Sequence:
MRVVVQGPGSLGSLVGGVLAGGETAVTLLGHQSEHLTRVREDGLRVVQPDGTTRVTRPSVATDPSVVADADLVVVCVKSYDTASAARALGRQCDGAMVLTLQNGLGNAAVLAEHVPADTVLVGTTTHGAARTEPGVVRHAGGGETTIGRYRGANDARVASVAAAFSTGGMETTVTASPQRAVWEKVLVNVGINAATALADVDNGALVECPPGERVLERAVTEGVRVAEAEGVSVSESVVERARQVAARTASNESSMRQDLAGGARTEVESLHGAVVERARDHDIAVPVIRTLADLVRLAQRDG
The following text describes a protein:
Function:
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping by DCP1-DCP2 and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails, trimming the tails from their synthesized length to the slightly shorter, apparently messenger-specific length found on newly exported mRNAs. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1. PAN cooperates with protein kinase DUN1 in the regulation of RAD5 mRNA levels and cell survival in response to replicational stress.
Miscellaneous:
MISCELLANEOUS: Present with 1600 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal zinc finger binds to poly(A) RNA; Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs (By similarity); The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.
Sequence:
MDKINPDWAKDIPCRNITIYGYCKKEKEGCPFKHSDNTTATTINDVPPPIDVGEATTPTMTSVPKFNAKVSASFTPMTVGSDSLTTVTNTTSAATNATGNIAMAATSATASTVNPMINPIVNSSLVNNNNNNSNISISIPTTASSSNYDPFNAPIFTPSSTSSIHTNANAHSFPFPSIANSGGININATDDNSNNMSMANNVPPPMQPPPIESSNLKYPRIYPPPHSLLQYHLYAPEQPSSLKSLLKPNERSADQLFIPNNIREDLTKKNLSILQVFPSSGKVIPSIVQDYFNLVPLNFNNNDFLNKTTLFKVFSNYDGKAYVLKRLPNIDKSMNPNKISKIYQIWSKINCTNLIKFRDIFQTTKFGDLSICLVFDYYPNSLSLYDYHFVNFPKFPITNNYLWIYLVQLTNVINSIHSQNLSIGNTLNWRKVLITGDPGRIKLSHCNFMDLLFNDDTDTVVSSGGSTIEGQQQLDYKYLGELLFNLSINIENSNNNTAPKEYRLEEITPQSIDDMRQIDDKFKDVLKYLISDNGDSKKSIHDLTSHFYDKMFMVLESSQTYTEYMESVLSRELENGRLFRLVNKLNCIFGRIESRIDINWSESGTKFPIILFYDYVFHQVDSNGKPIMDLTHVLRCLNKLDAGIQEKLMLVTPDELNCIIISYKELKDLIESTFRSITQ
The following text describes a protein:
Function:
Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs.
Sequence:
MIEVGILKIEDPGCFWVTKKGHGPFLNHEMEYQKLTIEMNNFYNHACRGEDLKPLMLEEGQVCVVYCVELKSWCRAVVKSIMPSADHHLAECFLVDFAKYIPVKTKNIRVALETFMQLPYRAKKFRLYCTKPVTLHINIYKDNAEIVPAKRWDSAAILYFNKILKATTQIEAKLCAEQEDFFDVYLYVTIKNEKICVNDELVAKNFACYDTPKESKFGTPENIVKCTTKINSKPLPSEINPALALWPTLFQEKIPECLGASIASQAPKLPIGDFSPKQVLGNECKEKEHISSNEINNSTVTSGCYLPKRDMTNLADSVEQTASVLSPKLNENQSKWTKKRGCGERNGCVKLLQFLNPDPIFADGTHYLQKPNISMQQPFTVLRNKIEPCSTFETAPLSRNLKKALRRNKFQGPNHTESYCWPPIARGCDSVVISHHGKDPLLYIPPILTFMQIGNCYKSLPSRNGPLAVILCPGWKKAMLVFDLLTEYSRGTRPLHPMLVLVGLYKEEAKNMKLQKGCEVIITTPHSLSRLLKYHSLLFLRICHLIFDEVEALFLEASEQMHTILDYFKKMSIERDSSPHQIVAVGTHWSKHLEILIKEFMNDPYIVITALEEAALYGNVQQVVHLCLEYEKTSPLLQFLDFTPSVTQKTLIFTSSVDEEELIYKAVVNSSIFCIKSHRDMGFDSKNVLEQWKKKFSSGTHVVLVLTDDCIPSLAITDATCVIHFNFPNSPRIYGDRLYCMSDNFQNLIEQGASVEQGVSKAKSILLLTEKSACHAVGILRYLERTDASIPPELCNFTAGVLEAKEDMKVGRPLCQYLKDFGFCKNKRMCPDRHRINTEVDIPNIFSEKTPNDGYITIIPFYIVNATNYFGRIIDKYEDLYAHLSAEMNEYFKESTNKVPVKKVEKLKLYALYEKTLFHRVQVLKIGQEENRIFFNVQIKYIDEGRTDNIKSYHLLHLPERFHSIPPQAVEFIVCRVKPIDNEIDWSPKVTRYIHNKIKGTIHEAKIVLSLGNTVWIDPMIHVTRLSDLKTSIIEYNIRSEILSLGMGTDNPEHAENLKKLFEEAKTATHEESTIQNSIFAKSPDTVKKLADDLQSTETEDEVTKNASSEMNPEDPKSDFESENKGQTDIKGTASRTYPKSYNPEIKWFQKEDNIILKLKIRNVKDHKCTFSREGVIFSAWVGDKFYLADLQLHKSIFEEKSKCIIKNEEPMIILVKEKKEPWLTLLKHKSPNVSFDFDHWEEPEEESPFSNVVPAKRMHHFPDRIIEEMDDSSGDSESESD
The following text describes a protein:
Function:
Elicitor of plant defense.
Sequence:
MENLRNGEDNGSLIPFTFFDQSSVTIPLLKCSGLESSSSSSSSCDLSSSHSEEDESIDIKEEEEEEEEDGMTIEIKARGKNKTKPTPSSGKGGKHN
The following text describes a protein:
Function:
Probable ubiquitin-protein ligase mainly involved in pre-mRNA splicing and DNA repair. Core component of the Prp19 complex/PRP19C/Nineteen complex/NTC which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity.
Subcellular Localization:
Nucleus. Nucleus, nucleoplasm.
Sequence:
MICAISGSTTEEPVISTKTGNVYEKRLIEKYIDTNGKEPTTGEPLGLSDLITVKIGKTVKPRPTTATSIPSMLQLFQNEWDSLMLETFTLKQQHETVRQELAHSMYQYDAACRVIARLVKERDAARSALANARNIVQQQQQQTNNNNNNNNNKDVEMSSASTPSSSEDNLLDSTIYKRIAEKSEELIKTRKERTHQSLAEPDAIKQFKVSANVETDCQIKSLEVNSQDNNLIAMGGINGNVYVYSRETNELCTAIKGTSSAPINKVLFAPNNTIVSAGSDAVIRVVKGGESPSKKTYTQYKSTYQFAHKASVTDISLHVLGDYIISSSLDKSLNMYDIVNGTHLTSFGQSQQLCYTSVAFHPDGMFFAAGTQNGVVKIFDLKSKVNSFNFQGLSTAVNCISFSENGYYLTAADNNTVKLFDLRKAATKNSPDIQTITLDNQQIKSINFDYSSQYLGVASSNQINLYSCKSKQKPPISSIHSIDSDCLDFKWARPNSNFFVTSSSSKNIVNIFSN
The following text describes a protein:
Function:
May play a role in phthiocerol biosynthesis.
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Sequence:
MISARSAEALTAQAGRLMAHVQANPGLDPIDVGCSLASRSVFEHRAVVVGASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQGAQRIGMGRELYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADLLDSTEFAQPALFAVEVASFAVLRDWGVLPDFVMGHSVGELAAAHAAGVLTLADAAMLVVARGRLMQALPAGGAMVAVAASEDEVEPLLGEGVGIAAINAPESVVISGAQAAANAIADRFAAQGRRVHQLAVSHAFHSPLMEPMLEEFARVAARVQAREPQLGLVSNVTGELAGPDFGSAQYWVDHVRRPVRFADSARHLQTLGATHFIEAGPGSGLTGSIEQSLAPAEAMVVSMLGKDRPELASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWETPGADGPADAAGLGLGATEHALLGAVVERPDSDEVVLTGRLSLADQPWLADHVVNGVVLFPGAGFVELVIRAGDEVGCALIEELVLAAPLVMHPGVGVQVQVVVGAADESGHRAVSVYSRGDQSQGWLLNAEGMLGVAAAETPMDLSVWPPEGAESVDISDGYAQLAERGYAYGPAFQGLVAIWRRGSELFAEVVAPGEAGVAVDRMGMHPAVLDAVLHALGLAVEKTQASTETRLPFCWRGVSLHAGGAGRVRARFASAGADAISVDVCDATGLPVLTVRSLVTRPITAEQLRAAVTAAGGASDQGPLEVVWSPISVVSGGANGSAPPAPVSWADFCAGSDGDASVVVWELESAGGQASSVVGSVYAATHTALEVLQSWLGADRAATLVVLTHGGVGLAGEDISDLAAAAVWGMARSAQAENPGRIVLIDTDAAVDASVLAGVGEPQLLVRGGTVHAPRLSPAPALLALPAAESAWRLAAGGGGTLEDLVIQPCPEVQAPLQAGQVRVAVAAVGVNFRDVVAALGMYPGQAPPLGAEGAGVVLETGPEVTDLAVGDAVMGFLGGAGPLAVVDQQLVTRVPQGWSFAQAAAVPVVFLTAWYGLADLAEIKAGESVLIHAGTGGVGMAAVQLARQWGVEVFVTASRGKWDTLRAMGFDDDHIGDSRTCEFEEKFLAVTEGRGVDVVLDSLAGEFVDASLRLLVRGGRFLEMGKTDIRDAQEIAANYPGVQYRAFDLSEAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAFRFMSQARHIGKVVLTMPSALADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLASRRGDRAEGAAELAADLTEAGAKVQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKVDAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANAFLDGLAAHRQAAGLAGISLAWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVATLLDRAALDARAQAGALPALFSGLARRPRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTATGLTLPPTVIFDHPTPTAVAEYVAQQMSGSRPTESGDPTSQVVEPAAAEVSVHA
The following text describes a protein:
Function:
Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNDFGALCIITSFAILIFSILQTSYGIWKRDEKTIELGRYTLMANTAVILLGFIVLLVQLFRTDLSNYYVVMHSNEHLPLFYKLTSIWSGSSGSLLFWNLLLSIFTFIVLWQTKDLTQDRIPVLNLTLAVISAFFSYLAVFYPDAQPFREFQPAAVAGRGLNPLLQHWAMVIHPPILYVGYVSFAIPFAIAASALITGHLSENWFRFVRRWTIFSWFFLGTGILLGSKWAYEELGWGGYWAWDPVENASLMPWLLSTAFLHSMIIQERRGMLKFWNMLLIILAFHFCLLGTWITRSGVLEGPHSFSKSTIGTPFIIYIGISFLFFLGFLIYRRNSLKPEHNLDAMTSKEGSFLFNNFLLVIATLAILLGVFSPLLYGREFKAPWFNSWGVPAGILLILLMGAAPLLAWRKGADKIFFSTLLKPLLAGIAGAGMYILFYTKNFTISEYSLGDVLGEIYSVIAVGLGIFTTAGIVQEYHRGIIARKTAYPNENYFFSGFRMLLKNKRRYGGYLVHLAMVILFIGYAGNAFKQNTSIKFFYFLNAPEKNEIVYSSQDTGVLGNYQISANTLKIKPLVSGEAKNGLNIQNVIVSHEATFQVKRNLKEFSTMVTERRFYPQISHLSGDFETHIPTSEPAISSTPKEDLYIQLGAIEHSDLSDENPDLPILFMNYLFTNENQPVRKLENFNRFPRQLVANLEVWVNPLVKFIWVGSLLFFFSGLLILLPIGESRS
The following text describes a protein:
Function:
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
Subcellular Localization:
Cytoplasm.
Sequence:
MFLRRSASSFLASRPAVLRAACFSSVACEPKPLTDTLRELRASEHFDLIVIGSGPAGQKCAIDSAKHGKSVAIIDKRDMLGGVCVHTGTVPSKTFREAALHLTGYRHKAFYNGQAGPSKRFGVEDILQRVRKVEDAETDITRHQLMRNGVQLINGTARFLPGNKNMVAVLSNESYETATDAKRHTSADICKRVLTADKFLVCVGTRPARHPDIPFDGETIFDSDQLLWGKVKTVPRRLIVVGAGVVGMEYASMMTIIPGTDVTVIDGRKEILNMADKEVSEGLCYSMAQTGTRFLTEETIKSVEKADNGEIFVHLESGKTVVGDGLLYTVGRQGNVEGLNLEAVGLAPDKRGRIKVDNNFQTAAPHIYAAGDIIGFPGLASTSMEQGRLASVHMRTSKPLNNQVLSDDKKMDDPDRVRTRMRSGEVFPFGIYTVPEISMVGKNEQQLTKEQTPYEVGMARYEELARGQMLGGVPGFLKIIFCPDTLKILGVHAIGEGATEIIHIGQVVMSTGGNLEYFRNAVFNYPTLAEAYRVAALNGLRKIDRLRDFDA
The following text describes a protein:
Function:
Binds promoter DNA and regulates initiation of transcription. Regulates mitochondrial replication and transcription. Required for normal topology and maintenance of mitochondrial DNA (mtDNA) levels. Regulates mtDNA replication by re-activating replication after replication pausing. Likely to regulate replication pausing by coordinating with the mitochondrial termination factor mTTF which promotes replication pausing. Their function in replication pausing prevents unregulated replication that may occur for example by collisions between the machineries of DNA replication and transcription during mtDNA synthesis. This ensures the incorporation of RNA transcripts into replication intermediates at the replication fork and allows for proper fork progression. Possibly functions downstream of Dref which activates genes involved in mtDNA replication and maintenance.
Subcellular Localization:
Mitochondrion.
Sequence:
MLRNGQNQAQLLARSLGQLARGMASSKRVSSKKEDLKPKLPKPPTVEIPMEEPLNASYLSKTLGSSYRSWAAALEKHPELKTLKRKDLLSSYDTLKSLDYSVDDIIAKPMIIYYGATTLANRHSVLQECGFHNVTVQTLAKYVTVVNKPIEVLKAHNYIPFDVKVAERLAGYFKDIKLPVDLRELESETLTLKSLRQSLINAYLRERLQMDDNDLQKLWRVYTRIRHKSFRAVQDTIELLTKEFNFSAERLRKNSFLLYSEADNVRRILREVPTIDSQDIREIGFRRPKILMSTCDSLKQTLQHVHAFGISEDAVLRCLEVLTLGPDTVLERLRDLQEIEEFQVLGTNPRILRLVHYQNKARLRLDYLNQLRVRCASLHILSCGSEAFAKFARDGSDRTKGRDIVVYLSNVLGKDVQVLRNLLSRHPNWCHIPLLHVKQCLEYLRSKKFKLNEIFANIHLLLYPIKRIEEKMLLLQSPDAQEDLQLPVANFDSLSNNEILTLILYLIESEFHFTGDGIWTEQHTHHVENFNNLLPDFPESLNKVYKYGVKPAEKMIMERL
The following text describes a protein:
Function:
Required for assembly of the protein secretion apparatus HSI-I. Actively secreted during chronic infection of cystic fibrosis patients.
Miscellaneous:
MISCELLANEOUS: ATP hydrolysis by the first AAA domain of ClpV1 is required for Hcp1 secretion.
Subcellular Localization:
Secreted.
Sequence:
MAVDMFIKIGDVKGESKDKTHAEEIDVLAWSWGMSQSGSMHMGGGGGAGKVNVQDLSFTKYIDKSTPNLMMACSSGKHYPQAKLTIRKAGGENQVEYLIITLKEVLVSSVSTGGSGGEDRLTENVTLNFAQVQVDYQPQKADGAKDGGPVKYGWNIRQNVQA
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MGLDSSGRGGAAAMDEGGGGYLVAARATLMQTMERTKEMEAGIARSRQKLQGMREALPALEAAMRPLQAQALLQKGLGAKIDRASQPAEQVLRTFEVVRSLERILKGEPRHDLPEYLASLSQLEEAMGFLSGNCVRAVQWISDAVSFLASSKTADKYRMYRLNERLASVLQDMQSEADRGSNYDMGLLQVALGKLDLEFRRILLQHSAPLPPSELVLPPPPTPAPAPADSNSEFGAGVGVEEEPVSAPLPVLMPAEVTETLRTIVERLEGHRWTDNVLEIYRESRLAPIRQTVQEQMRAEYLVHGSAEKIDKLAWEELEGMIAQWTQHVQVACRVVFKAERRLCTRVFATVEKERWIRCWGRLGAAGFLPFLAFGEGVAQSETAPAKLFKLLDMYETMDQLLASVFEVFEGADAALGEIRVRARELQRKVVVRASETLAEFGRSVEEGAGDAPANGERSRLCSYVVNYVKYLVSDFYGPIMAKVLRVHNRRDGEGDESRDRDRWLAAGVQRMMQALEKHVTRQGKSYEDASLGHIFMMNNLWYMVSRVKDSELGPLLGDAWVKDTRGKVRQHTLYYQRETWGRMLAFLTREGLAVSSGNRGATRELARQRVRSFTQSFDEVTLRHGKWVIPDAELREGVELAVAQMVVPAYRSFIQTFRSLLDPGSTVGSRHIKYSPEDLERILDDLFQVRRAQDSKPRNGTTDGNLGDG
The following text describes a protein:
Function:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. FOS has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Sequence:
MISEEKMHPDSSSELQPSSSCSATSPGGDSPGSRQHPPDSLSSSVDQDSDLSAGAAFVPTVTAVSTSPELERMVQPTAITSAALKNKAQGAKQTPAGSKKAKPYSRKGQREQPSKEEEERRRIRRERNKIAAAKCRNRRRELIDTLQAETDSLEEEKSALEGEIASLLKEKERLEQVLASHNPTCRLPGDASMEEDAVDSIMQDPPASPHLLSILEKPPESSTDVPTAPDMASASCIPAAAILGNSNILLCSSAEEDDLEDLTGEDLDNLVPSLEMAVTSETAVSVPDIDLSGPFSLPDWETLYKSVANDLESFSPSVVSSSPSCSSYRTVFSFNYSEIESLAGGCDSVKGGLAASELIKDSLNSPTLLAL
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MVKEMPSSTVVNRDEECLKKSLMEVVKSDSSNLCRLCLSKEQKLTRAFSDERGIDDALLKKIFDCTTVKVKLKSVFPSAICAVCDLKLNEFYKFREKCIENDTFLHNLLDDRVVAASEVDQSVPTVEKQPKQQHLNRTSSKGGSGGSGSGGTHVKEFQTEQQAATSTTSIPEAQKRNNSEMMAIALNQLSSFGLRPLQELMVERNGTERHALLDDRSSARLPTNSGGNVVSSSSCAASQAHDSTVPPPLISSLDLVEQTKRQLEQQERTFALATLEMAGLQALHRTGTEGGSVGGSGGAGAGSTSGGKFECTVCRRMFRNAYTLRRHTNLHTETNLFPCEYCGKKFNDRSNWKIHQRTHTGDNLYTCLVCLKTFISPSTLKYHRRSHRRLESFDCRLCPGTFANYDLLEEHARNMHQDMQDMQPEEPMIDAASFVKIELEDGELSSSMAGGDVGTTTTTRLQHGNEEEEEEEEEEQESRERRQPVDSSGVEELHLAELYQTQQQVLELLEKQLQGGHVTVEPRIGAMAANGGGMGEQTMHEGGMAVKREMLVEHQQQYQQQRQHEVEVKEEPLDDSMEIDPSELLQQAMEEAGDGNEDSEGGDKQFSSSSSDDSSSPSTMILFRCDYCMKIFHFLDELNAHMLLHNGAKKGNAATGPIMLGTAAASNTSGPVPSTPSSKPMPLLTLVRPESSIPLLANGYATKAESKSPRSKPKRRRATTITVAPEEQTKSIPDAVSDSLLPPVPAPPPEHVCSKCPKMFRTEELKRVHEATHADDEQAHKVRSCRICNKLFKCELNLLAHMRKHSLSIHQTGLAGEGAESGAGDSSGNDESCSSSSNVGGGGGVLTAAASHELTAVQNHQHFSPDESDEGESPPGAPPSDVASPEGGEPAGEGTDSASLAVLSRSAFRKCEICAITFKDTVALDQHMLCHFERKEAIAFVPQTDRPFQCTECHKSFKRKDYLLIHIRTHTGERRYKCDLCSSAFVHPSNLITHRKLHSNERPYQCTLCGATFKLFAGLKIHRRRCEQKLPKGGSQENAAGTAVLSFGPDTAELHDSGTTAEQLLSAGSVHYPF
The following text describes a protein:
Function:
Transcriptional activator. Binds DNA on GT-box consensus sequence 5'-TTGGTT-3'. Plays a role in spermiogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MAGSHVDMAPASTTEGTGEKPGPTAPAPTPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCPKAFKGSSALLYHQRGHTGERPYQCPDCPKAFKRSSLLQIHRSVHTGLRAFTCGQCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGICGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHHRTHGPAPGPAPAPAPPGETSRADTKVLVSDAYLQPRSPPEPPAPPPQPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGPPVATQSQDVPAELPQADSALPQPPPATPGPPNFACLPCGKSFRTVAGLSRHQHSHGAASGQAFRCGSCDGAFPQLASLLAHQQCHVEEAAAGRPPPQAEVAEVTCPQEPVAPATPAPPPPPPPAPVVSAERPYKCAECGKAFKGSSGLRYHLRDHTGERPYQCGECGKAFKRSSLLAIHQRVHTGLRAFTCGQCGLTFKWSSHYQYHLRLHSGERPYACTECGKAFRNTSCLRRHRHVHTGERPHSCSVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFACPICGRGFVMAAYLQRHLRTHTPATTTSGTTGSAVASQPPAPLAAAPTPLAAQDVHVLPNLQATLSLEVAGGTAQPTPPGPAAPSSQTFLLVQTAQGLQLIPSSVQSPTPPPPPPPPKVILLPPASAGGPGSGAARPGPRSVGKAGQGTGVVWFPGPGGLGLQGGANAGASGGGQSLIVLQNVGSGETGPQEVSGVQLQPAQEVATVQLQPAQEVTTVQLQPAQEVTTVQLQPLTGQVSNSNGGAGTTEAPNLLLVQSGATEELLTGPGPGEVGDSEAGAGVVQDVLFETLQTDEGLQSVLVLSGADGEQTRLCVQEVETLSPGLAEPAATGPSGQKLLIIRSAPATDLLENSSVAGGTTTLQLLAPSAPGPVSAPVGVPVAPPSQMVQVVPAVAGPGVMAPQNLPSIQIVQTLPAVQLVHTF
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
SLRSDPLPRASLAPTADIAQASMETQLPTVMELDSSEPANFTQPSRRYSYLEKIRSLSVVSGEVAGWSSSASASSSRSARSSYYSSSMSSNASGGPHNHRYAPYSNSSPGDIDLHGAQDIARQMVHDGFMVNLIREFDRAPGPALERWFSELDVGWLLRSAAAADKEQSELGLADLVRRWTRGYTVMAEALSATQTKVAGVPAIILPQAQRDHNNIMCDQELEDDLRLQFARFVEATVSKMLAFVDALAAENTRLSIDNLSRLVGLCSCIYSCFYKCNVVVITDSEEIVDSELQCLGRKVVGAFIITTTTLCNAIESMAMVAEAVTPVLIGWDSCENFKQNAEIHEATRLIVDYVRLFWGYQSLRSNMRYLKWVQIPITMIPQMLINFEDQLEKISESFSDPSLRYLFLLNNSYFVREEFLEPSNYVFILPSGTTLKFMQYQEKYMLASWEPVLYCLHEKMPLWFPKHSSQLARFKSEFQKTFRHQKLWKVPNPRLRQKLREAIIDKVITGYKRYLEDHPELEKCSSDLQDMEDMVNELFEG
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSTSLSEQLKRLALPQTSLLQRDKKRPSLLFDPKEAAGLKRETVYQIGLDGLEELITKNPVFEQFKSNIFHITSKKFERAVQSADANKKLDKVIRKFLLQLSPYFLLNCAHKALEWLINRYNIHEFNRDDLLMLIMPYHESNIFVRVVQLMKFKDENDSWFFLKSIQKTGVHLTKQSLLNKASSDVYFLKFVAKFISLLVKQFEKPSLLTVAFNFYCTVFVGAIEYSSELNEAQITQMLPALLKGLNSDIPDFCAASYVILGRLVMKTPLTDAILDKFVEKVSVSKVETLKTESVLTLLILCQSQTHYTQLPESACYSLIGKNWLPKVLQDLSNGNCFVTPFLKVLVKTCLYGAVKLDLEEYRAFMKTLLAAIKFDDAFMEIFLSLLLDRTKTKKPYSEHLQKWLTEIIETLERQYPDQFDKEVYKILSTTQQGKVIKRRKSLQKILTETMNIRCKFDVLAKLYHPNVTYRKEAIKYLVNNYDSLRDREKEMIKSSFIDRLNDDSVEVVHETLNLIKNISVLKTDALKDVLTKLAYKCQSDLKTWGSVSTEIVLMLCEQSEANDWETFVAVLPYLLPNSENQLSAAQTIAESSFCRKNCLLKKINAKGEDCAQFCNSVFDSMRNNNKELVNDFIACIHKTTDRSVLSKYLIILILSIILPENSSIESNITIVKIFIEFIENCEIKYEKGNAFMQKHISVARAGQFHIEGFLLCLKNVIVKTLKPTVELGRVDLHEDTDFNQYFTLLATTLLKNKSNHKKYVHVFINYFCKTFRSKIEFLLNLVNSGKSQDLEFVTESVSLIAKLLSSVKDSNEMSSLLESDIFIPQLLALLLHKSEDVKQKSFRIVEILTEVKNDTFGHLFRELLDQREEIVVDNDQLPLIMFNYLSPSAVKDTKVSGNASTLKTLLIKTSCGKYPVYLKSKMLELLSHINTIEIFEETSHDCLHLLKTQSKNLDEVKSSIVVRNLQRCQPTIAGNIAVGTSIWTLIETCLKDSDFTLTVDSKPEFATVLLLKQFDREFFAQLDAKVETKLLDLIVETATLTKNPDVLPAVRHTIKVIELDAKLILSHFVKMRDVQSPKLDPNKLKRRISVVPTVDILDTLDWRKGLTALEFIQDKKKLTNIEVLFPVLFEILKKCLDFDEQAAVEYPKQLILLSILYLGEKIDRDSIGETTFNMELIVQCIRASQNPQTHYCALLVLAFSAELFPSQVLHHIMAIFTFMGSSVLRHEDAYSFQIITRIIDTVIPILVKDNNPETIARVLRVFVDALLDVPEHRRMPIYGHLLTKLQVKDNLYIFLLLIFESHVNHSHRDKNKEDDMKRLEIAASVCREFSPEIVIQNCINLMKYLKELPDEVDSDNTSSPFDIHYKTPKQFRHYKYTLIIFTARLLSSKEFVFQVASLKNDELLDLQQLYKDMIINILTYIYRISKIADKNANTQHAKYWKVILHLSYDILDSVNALLTPQMFLLVVKGLMLHNFSTIRRRSMELLNSKLQNNPSFFDDCTSEQIYSLIPPLISIIKNVEEAQSESDDELIVQTALLSLKLLTKFLVSDYHEKLAEILDFVTDLAKSGKVQNNVLASVLLCLAELCTNLRAHAIPSLPNFMPAILRILKQQKSQESSSLLLLSSVTTVQKIVETLPLFLSPYLEKLLYELSLLASNVAEEERLQPVVNKLSNLKQQIGTSIPPRVLIPVLGQSYDRLITKQAFSAVGFLLDTLAENLNHLNGSEIGANLPELTSFFLNALQFRTDQDTTFEQANEVEAQIVKALTKLILKLSESTFKPLYYKLFDWAARHEQKTERLITFYALSSGIAEALKSLFVLFAGHFLNNAAQILDSCNVTKTDALYFDDEKKNVLLLENVLKTLHSVFLYDSHKFVNKDRFEVLMQPLVDQLENTLGGVGGLERRNGELVTPVIVQFAVATADDSLWKQLNYQILLKMKHNSPEIRLISLNCLKEMVTKLGVDYLPLLPETIPVLAELLEDEEESVEKACRKAVQEMEKILGEPIEKYFKM
The following text describes a protein:
Function:
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular Localization:
Membrane; Single-pass membrane protein. Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MTIDQTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
The following text describes a protein:
Function:
Transcriptional repressor of flagellar motility genes, such as flaA, during extracellular growth at 37 degrees Celsius and during intracellular infection. Binds directly to the gene promoter region and probably prevents RNA polymerase binding. At low temperatures, MogR repression activity is modulated by the DegU response regulator in an unknown mechanism. Required for full virulence.
Subcellular Localization:
Cytoplasm.
Sequence:
MPKSEIRKLLQEIKKQVDNPGNSSTTEIKKMASEAGIDEQTAEEIYHLLTEFYQAVEEHGGIEKYMHSNISWLKIELELLSACYQIAILEDMKVLDISEMLSLNDLRIFPKTPSQLQNTYYKLKKELIQVEDIPKNKPGRKRKTQKNTKKEKTNIFGKVVPAEFKAPASIKEQISYDKSREKNLVDLLSGVKSNVQLLSENQGEENNVYDLLKSIYSLSSLAVQKEELDKKYQDLQTKCQELEQENSYLKQQNETMTDSFHTLVLQVADFAYASDLDQIQALPLFSQQLVVTLNQLGVFKENYKQM