lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the MMS22L-TONSL complex, a complex that promotes homologous recombination-mediated repair of double-strand breaks (DSBs) at stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication. It mediates the assembly of RAD51 filaments on single-stranded DNA (ssDNA): the MMS22L-TONSL complex is recruited to DSBs following histone replacement by histone chaperones and eviction of the replication protein A complex (RPA/RP-A) from DSBs. Following recruitment to DSBs, the TONSL-MMS22L complex promotes recruitment of RAD51 filaments and subsequent homologous recombination. Within the complex, TONSL acts as a histone reader, which recognizes and binds newly synthesized histones following their replacement by histone chaperones. Specifically binds histone H4 lacking methylation at 'Lys-20' (H4K20me0) and histone H3.1.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus.
Sequence:
MLRAAGARSRGRGLRLGAREVRIPASGGLSMSAERELRQLSKAKAKAQRSGQLREEAAACHQLGELLASSGRYAEALREHQHELQLLESVDDALGCAVAHRKIGERLAELEDYSAALKHQHRYLELACSLSNHTEQQRAWATIGRTYLDIYDHCQSKDTLLQAQAAFEKSLAIVDEKLQGTLAKRELNEMRTRLYLNLGLTFESLQQMAPCNDYFRKSIFLAEQNHLHEDLFRARYNLGAIHWRKGQHSQAMRCLEGARECARVLRKELMESECCVLVSQILQDLGDFLAAKRALKKAYRLGFQKPLQKAAVCRTLKYVLAVVQLQRQLQESEGSDPQGAMAICEQLGDLFSKAGDFPKAAEAYQKQLHFAELLGRPGPELAIIHVSLATTLGDMKDHRRAVSHYEQELRLRGGDALEEAKTWLNIALSREEAGDAYELLAPCFQKALGCAQQAQQPRLQRQVLRHLHTVQLRLQPQEAPTTAARLQELSVPGDEEEDEEEEKEGDSDTPEASDVELSESEGDADGLSQQPEEDEELQGCLGQRRASKWNRRNDVGETLLHRACIEGRLARVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLDIVRFLLDHGAVVDDPGGEGCEGITPLHDALTCGHFEVAELLIGRGASVTLRTSKGHSPLETLQQWVKLYGRDLDSETREKAGAMERLLRAAAAGQAPHGLPRSHLFDPEISPPLSPCPGSPEPPGARPWRNRHTLASSSSSEGEDGPARPTPKRPRHSVPAQQVARRPGSSSSRDTAAEVGPRGLGEPDPHRAALIPEEDWLAGDWLEDDSPLTHSHQDGPVPRPQGTSRGAPGSGSRSPGRPRPRARTRQSRLPHLTSWNAPIGARGEGGAAAEPPRSPNTSRASGPGGDSPAAGQPSGPPVPPPIRVRVRVQDSLFLVPVPHSKEAHSVAWLAEQAARRYCQACGLLPRLLLRKEGALLAPQDPIPDVLQSNEEVLAEVTSWDLPPLTDRYRRACQSLEEEEHQQVLQAMGCQGSGPSFSACSLALRQTQLTPLLRALKLHTALRELRLAGNRLADGCAAELLAALGTLPGLVLLDLSSNHLGPEGLRQLATGLREQTALQNLQELDLSMNPLGDGCGQALAFVLQACPSLSTLHLQACGLGPGFLLSHQAALGSAFQDATHLKTLSLSYNILGTTALARALQSLPARTLQRLELSSVAASKSDSGLVEPVVRYLTEEGCALSHLSLSANHLGDKAVKDLSRCLPCCPSLISLDLSANPEITRVGLEELLSALQMRPQGLGFLGLSGCAVQGPLGQRLWHQVAARVQELQLCSRRLAPEDRTALSLLAGPPIPGACTLDRGSRLFFRRL
The following text describes a protein:
Function:
Involved in the activation and reutilization of phytol from chlorophyll degradation in plant metabolism, including tocopherol biosynthesis. Catalyzes the conversion of phytol to phytol monophosphate (PMP) (By similarity).
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MMFLSFNMISGGNTLQRFDPVACVSSVPLLLAPTTRPTFHFPSPFLSKPKPTYLFTSFSSSSSSSSSFFSSTTPPRSTMLHHDPLVSDVYATAISGVVALSFLRLFQETAKRDLFDQKLNRKLVHISIGLIFMLCXPLFSTETWASFFAALIPGINIFRMLVIGLGILKDEATVKSMSRFGDYRELLKGPLYYAATITLAAIIYWRTSPISIAAICNLCAGDGMADIVGRRLGGEKIPYNKNKSFAGSIAMATAGFLTSIGYMWYFSSFGFIEGSWKLVLGFLLVSIVTAFVESLPISTELDDNLTVPLTSILVGSIIL
The following text describes a protein:
Function:
Stimulates mRNA translation.
Subcellular Localization:
Cytoplasm, cytosol. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs in response to arsenite treatment.
Sequence:
MTSDQDAKVVAEPQTQRVQEGKDSAHLMNGPISQTTSQTSSIPPLSQVPATKVSELNPNAEVWGAPVLHLEASSAADGVSAAWEEVAGHHADRGPQGSDANGDGDQGHENAALPDPQESDPADMNALALGPSEYDSLPENSETGGNESQPDSQEDPREVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVDEKGEKVRPNQNRCIVILREISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETEADAQQAYKYLREEVKTFQGKPIKARIKAKAIAINTFLPKNGFRPLDVSLYAQQRYATSFYFPPMYSPQQQFPLYSLITPQTWSATHSYLDPPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREPPALKSTPGAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKSPQ
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDPVPGAGSPEPQPQMLQIKKEEPDPEDHQTPMESSAAPLTDGDVDLTHGDERDLVNSKSLLPQCNSLARESGDASPNTPKVPLQGPTQHRLSLNHKAAGPETSGVICCNYGKCFGSDSGNQCAAVYQREHAPPICTQRGFNHDALLGLQIPRLLHTGEKPFSCTECGKSFCHKSSLIAHERAHKGEKPFTCAECGRSFTIKNRLTKHQKMHSGEKPFVCSECAKTFSIKEELQKHMWMHSGEKPFACTECGKCFPLKNRLTAHQRTHTAEKPFTCTECGISFSLKSRLNIHQRIHTGEKPFTCTECGKSFSMKNKLQKHVRIHTGEKPFTCTECGRSFSLKSRLIAHQRIHTGEKPFTCKECGKSFSLKKGLQKHLPMHTGEKPYACTECGRSFSLNCSLRRHQMVHTGEKPFHCKECGKSFSIKNDLQKHVRIHTGEKPFTCTQCGKCFSQKSNLQSHSKTHTGEKPFTCPQCAKCFSHKCSLRKHQKSHSNPKPPIEKPFQCGQCGRGFSYKFTLRKHQKIHVTPQSARDSQEPPMHFVSCS
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MRFTSLLAAVPFLSLVALAADPAHWSKLAAKSRDGVIKLDSKTYDDILALDREYSVTVLLTAIPAQYKCQPCQVFDPSYSQVADSWARLPKSQRDQHFFARLDFADGQAIYNQLGLTSAPTVMYHPPLAGPRRNNKLSVINYDLNRNGLSAPPLHSWVSGLTPSPFELHTPLNPWPFIFVPLSLIAIGVSAYSLRSILVPLIQSRIVWGTASIILILTFTSGYMWNKIKNAPYIAAGRDGKVQWIAAGYQNQLGLESQVVGAIYGLLAFSIVALSVLVPAQTSAVKQRVGVYLWLGMLVIVFSLLMKLFKMKNGGYPFSLLF
The following text describes a protein:
Function:
May function as sodium-coupled metabolite transporter across the chloroplast envelope; May operate as a cation/H(+) antiporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Plastid, chloroplast envelope.
Sequence:
MARSVDCASDSSVKNVALDTLFLIVLQAAVVIALGKFIHLGLRRHNLPSATSQIIAGIIVGSLGLHDVIVHVDVENAEDTYGRYVSEARIFYMFYVGLEADVGALWNDMRRATVFTYASVATCLLLAAFVSGGMYGSMMHTPVRSPELLAAVLMLSIADTASVDVSRMASEMGLAATPSGRLVVATAIATNIICIVGEGVFSCMKLASSRTPDYSAPQRLGLGILALIKVGVAVTVLRVVVVAFFNRRNAGRHRVGNWELVLLLFAVSCVGNFPQRVGFDGMPVSLLLGLAFPREGPVARSIIETLAYPLHALALPFYFGAMGMRLNFSAMSGAILVPATLLTLLGLIGKCAGTMAAARFLQMPTADALRLGVLLNIKGHVNMIDMSFASSEGIWAEQALMAMVVGSMISTIIAGPVFAVVFRKEKEAYECSHQALEHMGTDQELRMLACVHGARGTPGMLSLLELLASKPHAQPTIHVLHFFDVARKHDGPRHYHQTVQDSEHKHMSRRKDATTQVNWAVDVFTCANGLVIRQIDTGDRGSAVNAKTIRRWTEDVRSGILLIPYHKEQHYDGTMVCRREDRRQLNLKVLEHAPCTTAILADRPFRRSGTSFQLPIKILTSNQGDEKVTTHVAAVFLGGPDDREAVAVACRLAKNESVRLTVVRFVLRESTDDRVATTSADIDGDVSVVVDDPDEECVSEFQREYVAKERAEYAEKAVTGPMDVVEALRGMAGAYALVVAGRGGRQPAELVVGLEGWAECAEVGPVGEILASDESLEMGSVLVVQQKTVPPFHLDLPPPAPAN
The following text describes a protein:
Function:
Bifunctional nuclease with both RNase and DNase activities. Involved in basal defense response. Participates in abscisic acid-derived callose deposition following infection by a necrotrophic pathogen.
Sequence:
MQGRCSLRVQQRCRHGRIAGLRSVVLTCRLLSAARSVTSAATPPAAGAGAPVAATQDASCPLLAMPWSRRTALLGFSVLSGVALNLGGSGTAAAAPLLRSMGWTVESELTVLNDLEHPIKIYWLNYDGDAELFGSLNPGSVFTVKTYESHAWRFVDSSTGYTVAEHVAAAGQQVVRVASKTGGVVAYTTAQSPGLAAPQQRTLAGRGSGGAGLAQQEQLAAPSATEPPRPLEPSSPAPPPAAFEGFDGLGNDEAAYSLAQLREVSIYPGGGNVLLLLPGSDTPLEVALAGPEALSLVAATGSLEQRRPSTLGTWTRSLMASGVEVRRVCITRMVDGIFYSRIVLSRPNEPGGGSEAGASSLCSLDATPGDSLSLALALRRPIYVNNEVVRLHRSVMDVFIRRREAMEAAAASGVFDEAAEAEADRAAQDALDSITRAIPSAPRAVHDLQLDHTLSA
The following text describes a protein:
Function:
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Sequence:
MIRFPTAFAASLVLVSSLTACGFHLRNSLALPPDTPAVKVQSALQYSELAKLLRRGLKAAGATLADEDAKSGFAQVQVLSERWGDLPIAIDSQGRAQEFSLRYAAIFTVTTANGAILVPQQVIELSRDYVSPPVDATGTATEREILADELRKDMSASILRRIDSVVRARVERGESLESTPTAPLQPSTTPPVQPSGTPESSVPASLPPAPQPSNNN
The following text describes a protein:
Function:
Part of a potassium transport system.
Sequence:
MKAVVIGAGEVGYHIAKFLSLTHDVIVIENNEDALRRADELDVQVVEGNGANADILASVLPDVDILVAVTGVDEVNIVACMTAKLIIRSHPGWKETKTIARVSNPDYIDVPVTSRAQVGVDIMICPELALASEVAEVLSNPSAIDAEMFAGGKVQMMEFAIRPDNRYVGKHMQDLRLDDCCIVSAIFREKEIIIPRGDDLIKANDRMVVVGKPRAMENLESVFGDKESHRNRILLIGCGIVGFYLAKIIDKDENADLKVIEYRKSRCIEVAEMLENALILNGDGTDVSLLKEENIEDMDVVVAVTDSDEKNLLCSLLAKQMGAKKVIARADRSDYVPLFEMVGIDIAVSPRAATVNEVLKLTMGKGIETLATLEGEKAEIIEYTASRQSKIVGKTLSKVKFPKGAIITMVVHKDEVVIPRGDSIIWEGDRVIVFALSSAVPYVEKLFK
The following text describes a protein:
Function:
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Sequence:
MILNQKSNYFLDWKEVFENENPIFLEIGMGNGEFIVHMAKENLNANFIGIDVSKEIFRKAVSRVKRSGLKNIRLMRIEGSEFLCKFVKSETLSGVYINFPDPWHKKSHKERRLVNEPFIYLVSDRLKNEGIFIFVSDNEEYTKSVWGLLKKFDNFSPLWDHGLRRDFPEYYKTKYARKWLALGLPIYYIGFKKTGNIEIPEYVKEYYPLLNLSKEDLYMPLVEFKIKKEKSSEFIKDILSILPKGLIYRDKNALIKVLDFYYNEESIIADIVCVEGSFRQRFFLDISLKKEVLKISIHDSDDPDPTFGIHKTLAIFASILKEKFTGLELLQNTTRIKEV
The following text describes a protein:
Function:
Catalyzes the production of 7-dehydrocholesterol (7-DHC or cholesta-5,7-dien-3beta-ol) by inserting a double bond (desaturating) at the C7-C8 single bond of cholesterol. Essential regulator of steroid biosynthesis as this reaction is the first step in the synthesis of the steroid hormone Delta(7)-dafachronic acid.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MLIEYLIRITVMVITSERLLILMGLCDESFHFPVMIRVVFNAAVAIVIALVMSKLYKVLFAPLDLRRKLEDVGYVHHDHSVSREENIRDTQRRKKLGNTPPVFPNGWFKVADSTWIKKGQVKSIYFFGEQLALFRNKRGLLRALDAYCPHLLANMAAGGKVVNSDCLECPFHGWKFSGETGKLVDVPYAQKVPTFVSVKKWSCCEVDGMAYLWYHCDGGEPKWVLPSSVTINTLKYAGKTEHIINSHIQDIPENAADISHLDHLHKPVIGSDVEKTNESLLNNLIFHSIQASWKPPTDPNEPHRSTMSIKDNIHLSIFNIKIPLLYLEFEIDQIGPGAVHIHVRTPFFRGLMLQNVTPIEPFVQKLTHSFYVSPWVPVCIAKAFYLLETTQIERDILMWNNKTYFRQPVLVKEESALAKHRRWYQQFYSENSPRMNHRGDLVYPGKPKLADW
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
Miscellaneous:
MISCELLANEOUS: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA; MISCELLANEOUS: Was identified as a high-confidence drug target.
Domain:
Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.
Sequence:
MSVLLFGVSHRSAPVVVLEQLSIDESDQVKIIDRVLASPLVTEAMVLSTCNRVEVYAVVDAFHGGLSVIGQVLAEHSGMSMGELTKYAYVRYSEAAVEHLFAVASGLDSAVIGEQQVLGQVRRAYAVAESNRTVGRVLHELAQRALSVGKRVHSETAIDAAGASVVSVALGMAERKLGSLAGTTAVVIGAGAMGALSAVHLTRAGVGHIQVLNRSLSRAQRLARRIRESGVPAEALALDRLANVLADADVVVSCTGAVRPVVSLADVHHALAAARRDEATRPLVICDLGMPRDVDPAVARLPCVWVVDVDSVQHEPSAHAAAADVEAARHIVAAEVASYLVGQRMAEVTPTVTALRQRAAEVVEAELLRLDNRLPGLQSVQREEVARTVRRVVDKLLHAPTVRIKQLASAPGGDSYAEALRELFELDQTAVDAVATAGELPVVPSGFDAESRRGGGDMQSSPKRSPSN
The following text describes a protein:
Function:
The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein: it acts as a negative regulator of bone formation and is required to limit bone formation without impairing bone resorption or mineralization. The carboxylated form binds strongly to apatite and calcium; The uncarboxylated form acts as a hormone secreted by osteoblasts, which regulates different cellular processes, such as energy metabolism, male fertility and brain development. Regulates of energy metabolism by acting as a hormone favoring pancreatic beta-cell proliferation, insulin secretion and sensitivity and energy expenditure. Uncarboxylated osteocalcin hormone also promotes testosterone production in the testes: acts as a ligand for G protein-coupled receptor GPRC6A at the surface of Leydig cells, initiating a signaling response that promotes the expression of enzymes required for testosterone synthesis in a CREB-dependent manner. Also acts as a regulator of brain development: osteocalcin hormone crosses the blood-brain barrier and acts as a ligand for GPR158 on neurons, initiating a signaling response that prevents neuronal apoptosis in the hippocampus, favors the synthesis of all monoamine neurotransmitters and inhibits that of gamma-aminobutyric acid (GABA). Osteocalcin also crosses the placenta during pregnancy and maternal osteocalcin is required for fetal brain development.
Subcellular Localization:
Secreted.
Sequence:
REVCELNPDCDELADHIGFQEAYR
The following text describes a protein:
Function:
Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
Subcellular Localization:
Secreted.
Sequence:
MNNILVATSRDSMTPEELLAVLPNHSLDPTLQPIFLGLNDKTRTLSCMESGDGEPLLNLVERNILDLYSSHEESKSFTFYSRSNNQQQTCCFESAAFPGWFMSTSTEINKPVRLSREGGPDITNFFCERKDPLE
The following text describes a protein:
Function:
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
Subcellular Localization:
Nucleus.
Sequence:
MSPEEYVRVWPDSGDLGGTELTLALPGTPTNASEGPKKFGNKRRFLETVDLKLGEAHENNYISSMVTNDQLVGWPPVATARKTVRRKYVKVALDGAAYLRKVDLGMYDCYGQLFTALENMFQGIITICK
The following text describes a protein:
Function:
Displays low GTPase activity and exists predominantly in the GTP-bound form.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MPSPLRSHTPTSPPRARTRPLPTERPFASDTPLRTGSVWGSSSRREPSGPRPPPPAWKMPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYQLIVQIKGSVEDIPVMLVGNKCDETQREVDTREAQAVAREWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGKRSSKQKRTDRIKGKCVLM
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.
Subcellular Localization:
Nucleus envelope.
Sequence:
MSSILGKRKNEEVVSFSPLKRISVEKSLLDSTAYNNSLDWLRSKNFKVSCLLKHFNSKIINDHPLSGSCYTDIGYALINSRKACFILSYRQSLGTAEPPTITFPLPEEDSNGFSGQNALTAFVPSDASDKEPGLLIVMPISGRIAYWTSIGNALAQSYICPQGMESLIKLLPKEKCEHLCCSNPMKFIISTNFGRLFSVQLRDPAGQPDVSVQLFASDISTFSTILQKMKIFNYPSIHIIALKSPPLFSPYQHLLYVAEASGLLEIYDLKLENKLVSGMNLSPIFKQVLREGCPDASGLEVLDLTICPTNGNLVSFLVCWKNSINYRYMIISLDFSDISSPSVMNIHPLYSFSSKSLESSKLHYSSSGNSLFVVLTDAVIIVHVQEDDKDIVSRTSWEEVIRMNTNVSGGIFMSTCYKYVLGKYSIPTESCFIATPYSGIAEIEVHSLEHPANNESLVKSKLEEAVFYSFLPGNPIDFSCNYLRSIKKPELERIIVDLGMDILNSRSTHLPPLFASLMQHLSCRLNSLNNLVRYIRSMSLDVDRQVLYKLRVMGEKCNSVRYLWNTIDTEFSTVSHSLIFQRIIYRLTQSASSDNALREWFLHNIESIDQLIAQAHEFCIDSGSRVQELPLEVLDVIMEANEVILAIQSSALAYRRESQKIYKLSIDTFGEEVPWTSTPETLVLLCRQFELTRSALVQSHQGTSDVENTFKIKDKGVLRNVVSNLEVQLVALTEVCFDAYSERIRWIEQRCGKDASEIQDVKEAFAVNRRFWVQTLSDIGKGSSAIRIAEKYSDYRSLVELCYQLYEDNELTDALNNYLDLFGIKFAFILYDYFVENGMALELLNSDRFNKSYLKQFFKSRDYNQISWMHDMRLGDYDAASHRLLQLATKQEKLVDKKESELSLSKLFLYAVPSNSGNIRDLVLVEQKLEQLHIQKMVSKSVMPVVERLRSQGKKYQLVEAVVDDLIGAKVAPVIARQVMQRVVKKFIAGQVVEATELLEYLSFSLYRREDLVEGEVTDYYLALRLLLTTRLTDDAKRFYENTIWRRAVLHDNWIQVLDTQGKNDAIIETQFRMSALYRTLEAVTINGLFHEGLIRPGSLSSCKFEGYDPQNLISIYPPARFGDVTEVTKVLNRESVKLDHYLTKTNLNTCYISMCLSCDTI
The following text describes a protein:
Function:
Needed for flagellar regrowth and assembly.
Subcellular Localization:
Cytoplasm.
Sequence:
MRITMSGERKRGFIRPGTDDATVTPQRWGLPDYGAESNKAAKQTAFNYDPGWIPNFDEPEQVVEHEFSEEEIALIRTAAQQEGFEAGQAEGYQQGFEQGKAEGFQAGHQEGQTQGYQDGVAEGQALIQEQVKTFMALANQFAQPLDLLNAQVEKQLVDMVLALTKEVVHVEVQTNPQVILDTVKASVEALPIAGHAITLKLNPEDVEIIRQAYGEQEIETRNWTLLSEPALSRGDVQIEAGESSVSYRMEERIRSVLKSFCGINRHHPGE
The following text describes a protein:
Function:
Required for contractile events in embryos that occur prior to mitosis, such as cortical ruffling and pseudocleavage. Promotes membrane ruffling by organizing cortical patches of septins and myosin II. Not generally required for cytokinesis in mitotic cells. Required for the asymmetric cleavage events that extrude the two polar bodies during oocyte meiosis. Not required for meiotic contractile ring assembly, initiation or closure but is required for the transformation of the contractile ring from a disk above the spindle to a tube around the spindle midzone. Promotes astral microtubule-directed cortical myosin polarization and cleavage furrow ingression. Regulates neuroblast cytokinesis during mid- to late-embryogenesis and is required for ventral enclosure.
Subcellular Localization:
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Midbody. Cleavage furrow.
Sequence:
MGDQFDSLMERIRVRQAEMSGEGEVAKENGPVTSKITSVKQEVASPTKVFGSSSKCNDGPSTPVHFHPQEPKETTPNMKENAENSLNSFKDATVNESSSKKTSRFSMLAQEIDEYEYDYQSQYNKPKEAYMKGRSPRMSIGETRPAVLCTPAGAQAMKSPNVAVSSKSAPEIALGMSDFEARRIKFAQPIVNVNYLPNESSIFSGGSGSSVNDQSTVLGGSAEMMNVTTSSLSCGELSMNQHITHENTIINAQSCDNREAILRERQQVSNEEYGPHTFMRKKVPKEASSATSSSSSTTTLTTISGASGSTTSGISNAPQDSASTKTTTNTFTSSYLLTKTSNNNINALVSSSPKPFSKDIGRSMFSPVHFTPKSTSSPKTLSESIFSPSKSAAVEGSIATTRRLQFEEKLKKSSSANVTAPPAPTSAPVPTPRHVAPLAPTVAQQSHLTPNHRHAAQQKKHLFPVVGIVATAPIPVQTQWRGQSNTPVVQGARADEKTAGNEPPVGAGVGKLKNLKSRWEFSSATGTPIHPDATEDSLIATAIKMKESAIPKQLGHRSERKGPSASSLYSQGARSNTASPASKSTRYEQEEEDDVFEAPEFNDGGDVISEDGILQEEEEDTSKFIDNAFGFMEGSGAGTPSPYREPPLQRLEKNRPPAEVIEEETENEDESEPYEPEEEEDDDATTQFPVPERSRKSSSQLAYSVSFYRKIQRDRNEESSTVLAGPVISQISPSAPPMSSSLTSQQKLRQLTTGPANGARIVESAKDAHDRIKRAIQVEEQLVAQSKRAMILARDKPSFRGSREEFEAQWAMLRHVEKHRALLTEYDRLKRDGPRIIDGPRGTITVSQLSVNMARDYVSANIASSKKSDEVFYFAAILRYGEQVDVSKMVTSDGGLNRRGVLEFPVPLMLTGIPPDFRATVEIYGQRSMRESTSHEDKYKLKNSTFKAKTRNTFLGGGSTSSANQSLFVDPAASSSSTSSTTSNFNLLGTFSFDINCPGKHLYNMSHTVYPLEGITQMKVRKQAIDGADITYHGFLSMYQRTGEGLGSWTRYWCALENGEMKFWKQPEDEGTKGYTALMDLSTCCRSEGASVVEDICPFPNSFHIDVWAPKMDTSDPRGIERLRVMLAADTAQDLQTWLSLINSTSKQLCTWRNPIVNQ
The following text describes a protein:
Function:
One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MSNTGTTGRIPLWLVGTVVGTLAIGLLAVFFYGSYVGLGSSL
The following text describes a protein:
Function:
May have a role in germline development.
Subcellular Localization:
Nucleus.
Sequence:
MEYEKMLYMPAASEMPHSPQLKPHQFQAHTPTDQYSSYADNFDLSLLPQESASIPTTVFQYNAPQIKVECAWDSQPIQQQQQPTAPYTNPSSHQLIPPPAYPHSAYPSPQSSPLQSEFAAYGLGRFGGSYDSLNSPSPSLEAVSIKQELHILPPSPPESNCETPSPRSSCGESIKAEPLDADIESLIDLNSLLQQQSLQSPQNLQDTKPDHQLLRECLEDTSFQKRHNLKPLALESFIGGLAEVRGDFEPVISLALEHAKREADAICAELQISQDPNGWSPAQVHAWLRSTLAQFRLPPVADLELHFCENGAALALLSEEEFVRRLPESGSTLHAQLEIWKMAYADQPAHQQHSQQSASTDHWPASYAMPHLDLDYNEDSEDDDDMEADAQVAPLNGSTTSPPATNASNGGTATVKRPNGGRTGGGGSHIHLWQFLKELLASPQVNGTAIRWIDRSKGIFKIEDSVRVAKLWGRRKNRPAMNYDKLSRSIRQYYKKGIMKKTERSQRLVYQFCHPYSQ
The following text describes a protein:
Function:
Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus. Note=Localizes to the apical part of cytoplasm.
Sequence:
MVTPCPTSPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDLFESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFRKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRLGDHPEAALEDCMGKLQLLVAINSTSLTHMLPVQICEKCSLPPSSK
The following text describes a protein:
Function:
Testis-specic protein that plays an important role in fusion of proacrosomal vesicles and perinuclear theca formation.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle, acrosome. Cytoplasm, cytoskeleton, perinuclear theca. Note=Localizes predominantly in the equatorial segment of the sperm head and neck regions, with some localization in the acrosomal segment of the head. Colocalizes in the acrosomal and equatorial segments of sperm with ACTL7A. Colocalizes with PLCZ1 in the equatorial segment of the head of capacitated sperm.
Sequence:
MDVNGHPKFQPSPETDGPLPLTSSTLMVSKSLQQDSLSMVGDRLPPKTGAVVIDMGTGTCKVGFAGQSQPTYTVATILGCQPKKQATKDQSELETFIGEAARSRPELRLVKPIRNGIVVDWEAAELIWRHILEHDLQVATHEHPLLFSDPPFSPATNREKLVEVAFESLHSPALYVASQSVLSVYAHGRVNGLVVDTGHGVSYTVPVVQGYNLPHAIQRLDLAGNHLTAFLAEMLLGSGFSLQQEDLDLVENIKHHYCYLAPDFQKEQARPDEECKQSLKLPDGRTVTLGKELFQCPELLFHPPEIPGLSPIGLPAMAEQSLLKVPQELRPHVARNVILCGGSSLFTGLEGRFRAELLHSLSPEDHVVVMAHPNRNLSVWIGGSILASLHAFQSCWVLREQYEERGPQVVYRKCY
The following text describes a protein:
Function:
Transports electrons between ferredoxin and NADPH. Provides electrons to heme oxygenase (pigA) allowing anaerobic heme degradation. Provides electrons necessary to reduce and mobilize Fe(3+) in a heterooligomeric bacterioferritin (BFR) complex to Fe(2+). Reduction of Fe(3+) in a pure FtnA BFR does not require Bfd. Reduction of Fe(3+) in a pure BfrB BFR does require Bfd.
Sequence:
MSNLYTERVLSVHHWNDTLFSFKTTRNPGLRFKTGQFVMIGLEVDGRPLMRAYSIASPNYEEHLEFFSIKVPDGPLTSRLQHLKEGDELMVSRKPTGTLVHDDLLPGKHLYLLSTGTGMAPFLSVIQDPETYERYEKVILVHGVRWVSELAYADFITKVLPEHEYFGDQVKEKLIYYPLVTREPFRNQGRQTDLMRSGKLFEDIGLPPMNPQDDRAMICGSPSMLEETSAVLDSFGLKISPRMGEPGDYLIERAFVEK
The following text describes a protein:
Function:
Required for the accumulation of subunits 1 and 2 of cytochrome c oxidase complex. Thought to play a role in either mitochondrial copper transport or insertion of copper into the active site of COX.
Miscellaneous:
MISCELLANEOUS: Present with 2550 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MLKLSRSANLRLVQLPAARLSGNGAKLLTQRGFFTVTRLWQSNGKKPLSRVPVGGTPIKDNGKVREGSIEFSTGKAIALFLAVGGALSYFFNREKRRLETQKEAEANRGYGKPSLGGPFHLEDMYGNEFTEKNLLGKFSIIYFGFSNCPDICPDELDKLGLWLNTLSSKYGITLQPLFITCDPARDSPAVLKEYLSDFHPSILGLTGTFDEVKNACKKYRVYFSTPPNVKPGQDYLVDHSIFFYLMDPEGQFVDALGRNYDEKTGVDKIVEHVKSYVPAEQRAKQKEAWYSFLFK
The following text describes a protein:
Function:
Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3). Involved in regulation of flowering time. Required for the expression of the flowering repressor and MADS box gene FLC. Involved in the control of seed dormancy and germination.
Subcellular Localization:
Nucleus.
Sequence:
MVKGEKRSEMMLNLFGDNSEEEEIESEHECNRRQPNYASDEAEGGVEPEGEGEAEVEVHGEAEAESDGEQGDVELDPGESEGEREQSSQEADPQEESEARDSDSDNKEEEHGGRVAKKRRQEVVESGSERSGEKHYESEDEEVDQTRSPRSPSEEKEEVQVAQSDVNIRNVFGSSDDEDAEEYVRNDVEQDEHRSPIEDEEGSEKDLRPDDMVLDDIIPEEDPQYESEAEHVEARYRERPVGPPLEVEVPFRPPPGDPVKMNMIKVSNIMGIDPKPFDAKTFVEEDTFMTDEPGAKNRIRLDNNIVRHRFVKSRDGKTYSESNARFVRWSDGSLQLLIGNEVLNITEQDAKEDQNHLFIKHEKGILQSQGRILKKMRFTPSSLTSNSHRLLTAIVESRQKKAFKVKNCVTDIDPEREKEKREKAESQNLKASTKLSQAREKIKRKYPLPVERRQLSTGYLEDALDEDDEDYRSNRGYEEDLEAEAQRERRILNAKKSHKGIPGRSSMTSARPSRRQMEYSESEREESEYETEEEEEEKSPARGRGKDSEDEYEEDAEEDEEERGKSNRYSDEDEEEEEVAGGRAEKDHRGSGRKRKGIESDEEESPPRKAPTHRRKAVIDDSDED