lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Spindle pole body (SPB) component that acts as the gamma-tubulin complex-binding protein of the SPB outer plaque. Promotes nucleation of all cytoplasmic microtubules by recruiting the gamma-tubulin complex to the spindle pole body (SPB), to the interphase microtubule organizing center (iMTOC), and to the equatorial MTOC (eMTOC) during anaphase.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Localizes at the interphase MTOC (iMTOC) and at the equatorial MTOC (eMTOC) at the end of mitosis.
Sequence:
MEENSSELDSNNFNVLVDNLAGLSLTDEEVRRILSPRKEGSRQLPSSTSKDEDSEEASHKYDFEIDRDSLKSDSGSPRLHQNATAPTSSTPLQSPDESVNKLNSEDEEGNSSVAPFFLDTTNFDRLNDNITTDDEQLSPVLTANQGFQSQEQYEEDSYNNYDYTSDPSSPNYISSSLDQLPHLDDEDDLQLTPIKEERNYLHSQDAPTTNALSKKISDILIPASAMKDLKDRKNALAKEFEESQPGSSLTLKEQANVIDNLRKEVFGLKLKCYFLYDQLNKFHDQEVQDIMKQNIDLKTLTMELQRAVAGYEKKISGLESRIKPDQSFNLSTPSPAPSNLITLQSRYSQALSELETTKRAFAALRKEKSKKTNYSVGAYNEDRNVLSNMLDNERREKEALLQELESLRVQLSKKVPMPAKNTDERVIETLQRSNELLRMDISMQNEALLLRKQENDRLVKQVEELTVALNSGKMNAIVEAESSKNELWDSMMVSRMKTQEQSIELTRLYKQLQDIEEDYENKLMRMEQQWREDVDQLQEYVEEITQELQDTKEVLSKSSKESDDYEEVVGKLRTEAEREIEKFEKTIRENEESISLFKEEVEKLTDEITQLSERYNDKCHEFDELQKRLQTLEEENNKAKEDSTSKTSNLLEQLKMTEAEVDSLRKENEENKQVIALKESELVKSNDNKLLLNEQIESLNDQLSQLKTEMESVTTSKESLADYLSNLKERHNDELDSLNKKLREFEGILSSNSSLKSEIEERNNQYVTLRENFDSLQNAIMETFDKQVTHCSVNHLVQQIRKLKDENKKDQSGTDKLMKKIYHCEQSLKEKTNSLETLVSEKKELKNLLDAERRSKKAIQLELENLSSQAFRRNLSGSSSPSERSQSRELKLLQASEKRLKEQVEERNSLIKNIVTRFTQLNTGSKPVNTNVEALTTISSMNQAVNMNFRELDKSIQEFKRKCQSMEREFKTELRKLDGVLEARSKRLSQLEERVKLLGAGSTSSIPNSPRASKRVSLDSEDKKLVPASPDKSAVQRGITALKRDAEGMSHIWQLRLREMEFQLKAEQEGRKRDKLGARERLQDLIRQNRSLSRQIKTDKESNSRSPSISSQEHK
The following text describes a protein:
Function:
Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is unknown (By similarity).
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MKSLNTLVILTSVISTSVFAGAYVENREAYNLASDQMEFMLRVGYNSDMGAGIMLTNTYTLQRDDELKHGYNEIEGWYPLFKPTDKLTIQPGGLINDKSIGSGGAVYLDVNYKFTPWFNLTVRNRYNHNNYSSTDLNGELDNNDSYEIGNYWNFIITDKFSYTFEPHYFYNVNDFNSSNGTKHHWEITNTFRYRINEHWLPYFELRWLDRNVGPYHREQNQIRIGAKYFF
The following text describes a protein:
Function:
Molecular adapter that acts as a bridge between a variety of multiprotein complexes, and which is required for embryonic development and for normal innate immune response. Acts as a regulator of embryonic myogenesis by bridging Twist (twi) with the SWI/SNF-like Brahma complex, promoting expression of twi-regulated genes during myogenesis. Effector of immune deficiency pathway (Imd) by acting either downstream of, or at the level of, the NF-kappa-B factor Relish (Rel). Acts by bridging the NF-kappa-B factor Rel and the Brahma complex through bap60 interaction, leading to activation a subset of NF-kappa-B factor Relish (Rel) effector genes. Not part of the Toll pathway. Required for the formation of the heart by promoting expression ot tinman (tin).
Miscellaneous:
MISCELLANEOUS: 'Akiraka ni suru' means 'making things clear' in Japanese. The name is given based on the presence of the clear nuclear localization signal.
Subcellular Localization:
Nucleus.
Sequence:
MACATLKRALDWESMNQRPPKRRRCNPFGQAGSNAGPASPSRDGPSTSAGLPHTPSNRFAKDSTEPSPFSESSLAKMSPDKMAESLCNEIKRLHKRKQLPITSSALERMQDSESSGSEMGPESPRRPDSPQNLMRHGEKALFTFKQVQLICESMIKERENQLRERYESVLTTKLAEQYDAFVKFTYDQIQRRYEAAPSYLS
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MTTAHRPQLEARNGAKGALVPTGTEHARLLPGHTELKARKPKNKTTSQIQTSSDAGSVDDSTSAGTNIGTGSATLGPSQVQKMIQPLEVEDKKDIKLVKKEDDSVSWGKTAFSRRKKVVKPEKFTNDTVRSQKHKEFLNRFVK
The following text describes a protein:
Function:
Catalyzes the final step in the metabolic pathway of hydroxyproline.
Sequence:
MLAVGRASPSIFRALSCSSVVRSFSSGSDGRKIQLGGIYPPLTTPFNVDETIAFDKLASNLTKYSQIPFAGYVVQGSNGEYPYLEKEEKLQIVKFVKDFIKGSNKPLIAGSGCESTKATVKLTEAMADCGADAVMVVTPAYFKVSMNDAAMIAHYTTVADSSPVPVILYSVPANTGIDLSIDAIQVLAKHPNIIGLKDSGGDVTRIGSIVQKTRGQDFKVLSGSASFLLPSYLAGSVGGVCALANVLGDVLCHMHSLYENNIIDKELQRRLIDPNNMVTRRFGVAGMKAALDLFGYYGGPNRSPMLSASAEARQVIKKAFLDNEFVPQSR
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MDLKKFWLPVFIGILVFSPCDAANSRNSSAKNWSKSLDATFPEQLRRGLRSCATVASPGEGGVCKILAAMDEQLKILAAPKNRDPPPRNSCKFKSENGASLHRYATDRSPALQALLDRYSTMHSACVARDHDNLHHIIAKNTAKITNPSQCRYIVWSCTFGLGNKLMSLVSTFLYAILSQRVLLLEESPSWDRLFCEPFIDSHWKLPRGLSLKDDQSISFPDFYARCRGHLSRSDVCRSQPVLPIVFSANTKPEEHRFLVCPSAMASVRNIPVLNFRNSNQYFAAGFFLNPSLRPILEAIFPERRVFHNLAGFLLNPSDEVWGSIQSLHSVKFRGASRRIAVQLRESKGDYRDYYDASVPRCIRSKSGLCPIEIDEFLESKNKSIASDDYIAVYVASLVGEHAAKLNASLRDVESQTGQRFELVTLGADEEQRDDVDHQQRALVDIWSLSLADVLLTSHMSTFGYTAQGLAGLTPYFLKPWRDDPCWPSVSSDPCFHFAPSKKLSCREDGFSLSARESGGGAMACPDLPDTGMQLLEP
The following text describes a protein:
Function:
P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation also seems to be implicated in vesicle formation and in uptake of lipid signaling molecules. May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes. Involved in acrosome reactions and binding of spermatozoa to zona pellucida.
Subcellular Localization:
Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDGVHLGENLEDKDTEFTWEVKANDRTYHKQFKKKGFLCWRQKKYKSNAIHTAKYNIFSFLPLNLYEQFHRMSNLYFLFIIILQGIPEISTLPWFTLFAPLVCLFVIRATRDLVDDIGRHRSDKIINNRPCQILRGKSFLWKKWKNLCVGDVVCLSKDSIVPADLLLLASTEPSSLCYVETADIDGETNLKFRQALTVTHHELTSPKKMASFQGTVTCEEPNSRMHHFVGSLEWNSRKYPLDIGNLLLRGCKIRNTDTCYGLVIYAGLDTKIMKNCGKIHLKRTKLDLMMNKLVALIFLSLVIASLLLTVGFTFMVKQFKAKHYYMSPTHGRSDAMESFFIFWGFLILLSVMVPMAMFIIAEFIYLGNSIFINWDLNMYYEPLDMPAKARSTSLNDQLGQVQYIFSDKTGTLTQNIMTFKKCCINGCIYDSDDEHGTLRKRNPYAWNPFADGKLQFYNKELESLVQGRQDRAVQEFWRLLAICHTVMVQEKDNQLLYQAASPDEEALVTAARNFGYVFLSRTQDTITLVELGEERVYQVLAMMDFNSVRKRMSVLVRNPEGSICLYTKGADTVILERLRSKGVMEATTEEVLAAFAEQTLRTLCLAYKDVEEDAYKEWEPEHQEAALLLQNRAQALHQVYNKMEQNLQLLGATAIEDKLQDGVPETIKCLKKGNIKIWVLTGDKPETAVNIGFACQLLSENMIILEDKDINQVLERYWEDNVHQKAFKMMTHHNMALVINGEFLDQLLLSLRKEPRALVQNAVVDEVAQEPVVSALDFLQKRRISQMWRNAGPSLGTSHSADSKIRESPEVQRERAFVDLASKCQAVICCRVTPKQKALVVALVKKYQQVVTLAIGDGANDVNMIKTADIGVGLAGQEGMQAVQNSDYVLAQFCYLQRLLLVHGRWSYMRVCKFLRYFFYKTVASMMAQIWFSLVNGFSAQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVTAEKSLKMPELYMAGQKGELFNYSIFMQAITHGTITSMINFFVTVMVSSDMSKAGSSHDYQSLGVLVAISSLLSVTLEVMLVVKYWTLLFVGAVVLSLSSYVLMTSLTQSLWMYRISPKTFPFLFADYNVLFEPCSLLLIVLNVALNVLPMLALRTIHRTVLKQRPKGEEEAPSEEVAVEPAMRHLRRGIPARRSSYAFSHREGYANLITQGTILRRQTHVDDSDGGTVCESLNPPEEDIPLQNKDSVFNPRKISILAKKRRHFFGKGSQEEVHPNTSSQTMEKQPTIHRDSETQKLPTTTSATSGKLLPSASEDEAFYSVASQYTLASQPKHTDVHSSFWKSPLWRDSASSSPSQLEVPRKQS
The following text describes a protein:
Function:
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
Sequence:
MYRLFVAIDLPGSVRAQLADLGRELDGVRLVPPDQLHLTLRFIGNADDECFQRIKDSLATVTSPPFTLALAGVGCFPSPRRPRVIWAGITPNERLTLLQRAVEKAVAAAGIPPEERPFCPHITLARLKEAIPEGFPAFQSRHGGLSAEPFTVEEFLLYSSTLTAGSALHRREASYRLTG
The following text describes a protein:
Function:
Component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is essential for mitotic growth and suppresses formamide sensitivity of the RSC8 mutants.
Miscellaneous:
MISCELLANEOUS: Present with 2470 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Note=Localizes to centromeric and flanking chromatin. Association with these loci is dependent on STH1.
Sequence:
MVTQTNPVPVTYPTDAYIPTYLPDDKVSNLADLKKLIEMDSRLDLYLTRRRLDTSINLPTNTKTKDHPPNKEMLRIYVYNTTESSPRSDSGTPADSGKTTWTLRIEGKLLHESANGKHPFSEFLEGVAVDFKRLKPLGMGKKRKRDSSLSLPLNLQQPEYNDQDSTMGDNDNGEDEDSAEAESREEIVDALEWNYDENNVVEFDGIDIKRQGKDNLRCSITIQLRGVDGGKVQYSPNLATLIGMQTGSVNDAVYSIYKYILINNLFVTEQTEAQDGSNDAEDSSNENNNKNGAGDDDGVEGSTPKDKPELGEVKLDSLLQKVLDTNAAHLPLMNVVQTVNKLVSPLPPIILDYTIDLSKDTTYGATTLDVDVSHILHQPQPQPNLQKEEETDAEDTAKLREITKLALQLNSSAQKYQFFHELSLHPRETLTHYLWSSKQNELVLQGDQYFNEDAARTSDIYSNNNNDRSLMGNISLLYSQGRL
The following text describes a protein:
Function:
Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
Subcellular Localization:
Cytoplasm.
Sequence:
MCISKWVNHGVYGELKDRPMFLQRPNAHLHVRLPRVLDASQIKSSLPNYNLPQRRRSQTPSPTAQPRSGDPSLSFPSFCRPRSLAFPSTMAAAAGGGAVRALSQKEQDIQMMLAADVHLGTKNCDFQTERYVFKRRTDGIYIINLGKTWDKLQLAARVIVAIENPQDIIVQSARPYGQRAVLKFAQYTGAHAIAGRHTPGTFTNQLQTSFSEPRLLILTDPRTDHQPIKESALGNIPTIAFCDTDSPMRYVDIGIPANNKGRNSIGCLFWLLSRMVLQMRGTILPGHKWEVMVDLFFYRDPEEAKEQEEEVAAAPEFAAITDYQGADQWGGDQWTSDVAAPPVAPTGADWGAAPAPVPTGEGWDQAGAPVPADGTVPPVVAPTGWDQAAPPTAQGWE
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MEDDEEETTASTLRGKPRPPPVSAQSAFSYIPPRRLDPKEHSYYYRPARTGIISLYDCIFKRRLDYDQKLHRDDREHAKSLGLHVNEEEQERPVGVLTSSVYGKRINQPIEPLNRDFGRANHVQADFYRKNDIPSLKEPGFGHIAPS
The following text describes a protein:
Function:
Not known; mutations in apaG/corD give a phenotype of low-level Co(2+) resistance. They also decrease Mg(2+) efflux but not influx via the CorA Mg(2+) transport system.
Sequence:
MINSPRVCIQVQSVYIEAQSSPDDERYVFAYTVTIRNLGRAPVQLLGRYWLITNGHGRETEVQGEGVVGVQPRIAPGEEYQYTSGAVIETPLGTMQGHYEMIDENGDAFTIDIPVFRLAVPTLIH
The following text describes a protein:
Function:
Involved in pre-mRNA splicing as component of the spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MAAIAASEVLVDSAEEGSLAAAAELAAQKREQRLRKFRELHLMRNEARKLNHQEVVEEDKRLKLPANWEAKKARLEWELQEEEKKKECAARGEDYEKVKLLEISAEDAERWERKKKRKNPDLGFSDYAAAQLRQYHRLTKQIKPDMETYERLREKHGEEFFPTSNSLLHGTHVPSTEEIDRMVIDLEKQIEKRDKYSRRRPYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTAV
The following text describes a protein:
Function:
May play a role in the transmembrane transport of tetrapyrroles and similar compounds, and thereby contribute to the regulation of tetrapyrrole biosynthesis. Binds tetrapyrroles and promotes the photooxidative degradation of protoporphyrin IX. Binds protoporphyrin IX, hemin, and coproporphyrin III, but does not bind delta-aminolevulinic acid. Can bind bilirubin, curcumin, gossypol, retinoic acid, cholesterol and the benzodiazepine receptor agonist PK-11195 (in vitro). Plays a role in the response to low oxygen levels and in the regulation of the biosynthesis of photosynthetic pigments.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Cell inner membrane; Multi-pass membrane protein. Note=Outer membrane proteins generally mediate transport processes by forming beta-barrel structures, and unlike TspO, their transmembrane domains do not contain any helices. Detected in the cell inner membrane when expressed in E.coli. This suggest that TspO is in the inner membrane, even if experiments shown in PubMed:7673149 suggest location in the outer membrane.
Sequence:
MNMDWALFLTFLAACGAPATTGALLKPDEWYDNLNKPWWNPPRWVFPLAWTSLYFLMSLAAMRVAQLEGSGQALAFYAAQLAFNTLWTPVFFGMKRMATALAVVMVMWLFVAATMWAFFQLDTWAGVLFVPYLIWATAATGLNFEAMRLNWNRPEARA
The following text describes a protein:
Function:
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
Sequence:
MIKSQKEYLERIAYLNTLSHHYYNLDEPIVSDAIYDELYQELKAYEEKNPNGIQANSPTQKVGATTTNSFNKNPHLMRMWSLDDVFNQSELQAWLQRILKAYPSASFVCSPKLDGVSLNLLYQHGKLVKATTRGNGLEGELVSANAKHIANIPHAIAYNGEIEIRGEVIISKKDFDALNQERLNANEPLFANPRNAASGSLRQLDSEITKKRKLQFIPWGVGKHSLNFLSFKECLDFIVSLGFSAIQYLSLNKNHQEIEDNYHTLIREREGFFALLDGMVIVVNELNIQKELGYTQKSPKFACAYKFPALEKHTKIVGVINQVGRSGAITPVALLEPVEIAGAMINRATLHNYSEIEKKNIMLSDRVVVIRSGDVIPKIIKPLESYRDGSQHKIERPKVCPICSHELLCEEIFTYCQNLNCPARLKESLIHFASKDALNIQGLGDKVIEQLFEEKLIFNALDLYALKLEDLMRLDKFKIKKAQNLLDAILKSKNPPLWRLINALGIEHIGKGASKTLAKYGLNVLEKSEAEFLEMEGFGVEMARSLVNFYASNQEFIRSLFELLNPKNSDMAEEKQKSSSVFNNKTIVLTGTLSKPRQEYAQMLENLGAKISSSVSAKTDFLIAGENPGSKLALAQKHGVSVLNEEELLKRLKELD
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
Subcellular Localization:
Nucleus.
Sequence:
MAAAEAAWRCLSQCEEDGQLTGDKLAAADLACKHLRRAIAKEEDGPSVPDCLRPMPSVLVTLVKNKSVSALRLIGALALHSLASNRALAQQEGLIHTLVACLADAGSGKVLEACVNALSDLATSDEGSAALVAQGALPVLMDRLIDLAPTCPTTPRKRKRRASNTPTALFPLLDAIFALLFCQAAPAIGELPRGRSSLALEALSSATSDAEIRGELSPKQTAKVCALAARFSLEGGAADFSFENDVTASAEAHGTAIEEARSGFGTLVGFGAAGLGGFLQTVWEQRPAFFPADTSKEPEADGRGFPWPLSGVKGSEDSEEFFEFLEGAVGCPSPAAEECDVITALREASEELGGPLVYGRDVTLVKTVAGQLVHFDGKTGQSGSASEAVSKVGSAESARTDVDGPGGSLPVTETNLANPRFVSAGDCREAFKNGFSVAVRGLQCRISEIAQLANNMALALGQAGVGVNAYLTPANSQGLAAHYDDHCVFVCQLAGSKLWRLYEPLESEQMPRLYAPRLEPELAGSICSEFKMRKGDVLYIPRGWTHVATALDVESLHVTFGVEVEEPFSWEGFLNAAVQAATLPVDLSGFPSEQSVEVPPKCPLSMRDPVSSPSGGGHSEKSRVSSGSVAKSGDPRPCCRCYEAVHVVADSIPELRKACLLGAVQGSGSLASSISNEPERNRMPAEVAHRSALRVAKVSEPSHSDGFGASNVKWNEDPEKSLASRPLGKSNIEHISVFESALDTAVSQIGVETKATSASTALGDFILTEAAVESEFEYIWGRVRAQALGKSEKCADRRLSAHLLEKETLQKADSSLSSNGSDGQAAADLQAEGKNGSCSGCIEAARFGTGKKQYLQRLREYQKARRLWTEAMIAVQSFLKGYHL
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Sequence:
MWFEILPGLAIMGVCLTIPGFSTILIHKYTNGGKEKRIARNHYQWSLMERDRRLSGTNRYYESK
The following text describes a protein:
Function:
Subunit of STT3A-containing oligosaccharyl transferase (OST-A) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Within the OST-A complex, acts as an adapter that anchors the OST-A complex to the Sec61 complex. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.
Subcellular Localization:
Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Sequence:
METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG
The following text describes a protein:
Function:
Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase; Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
Subcellular Localization:
Cytoplasm.
Sequence:
METDNNNNNNNNINLSLNNYIINNDSFEINLDYINQNNVIKELGDWEDVYSLPTRMTLDSFWFTMQKWSMNPSYMIRNVKKFSLINKSTYSAEEKLLSKFVFEKNLSGIFYENEINTINKPQNGQNNDDSQEEEDEKEEKKHKNDEKKKPNKHDNDGENEEDENIFYNKEIYTKDNNESELTEEYLDDNVQTIVYRRHLIPRLLNRDPTIDELIIHHKSNSCVQFIPLLPKEDNKNSRLLPFLYPKVLGFKIQYQKLDQEKDKDQRKKLSEEQQKEEFEQGEDNQFKAILKIQVIYFSNFKPKFDRVSKSILEKINRWGINFEIGYKKKANLDQIIPKNIFLAQYEEMKPRYRNMVEGWEDVTKTDPQKFIYEDVAIAAYLICIWRKENEELGKTTKQRFIDIGCGNGLLVNILNKEGYDGVGIDLRSRKIWSRYDAEVQKNLIEEAIFPKDTYYPDYDWIIGNHSDELTPWVPYITSKLPNQKFFLLPCCFFNFCAKFKDNDVRIGRYASYLNYIEKVSVECGFNVIKETLRIPSTKNIAFISDFRNPQLTEEQLVERRQNLLKSSNYIDFKPREREIKWVAQKRYRVDQFNPHLDPNNPENQKRIERLNNNNNSNNNDNNDIN
The following text describes a protein:
Function:
Transports the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Is probably involved in the import of pseudopaline-metal complexes.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MRVSVSLVLGVGLGCSSPALWAETESPAELEVLTVTAEAERAEGPVQGYRANRTASATRTDTRIEDIPQAISVVPRQVLDDLDSARIERALDFAGGVSRQNNFGGLTMFEYNVRGFTTSEFYRDGFSANRGYMNAPDSATIERVEILKGPASSLYGRGDPGGTVNLVTKKPQAERFARLHASAGSWDRYRSTLDLNTPLDEEGDLLYRMNLAVEDSKGFRDYADGQRLLVAPSISWQLDPDTSLLVEAEVVRNRQVFDRGTVAPHNHLGSLPRSRFFGEPDDGKIDNNNETLQATLRHHFNEQWSLRLASHYKHGHLDGYASENSSLAADGYSLRREYRYRDFEWHDSITQLDLLGDLHTGSIRHQLLMGLEYERYHNDELILRSIPSRNPYAIDIRRPVYGQPKPPFGRDDRNHEEVDAMALNLQDQIEFSEKWRGLLGVRFDRYRQDMNATRLNNGRFRETSSQQTQRAATPRIGVLYQATPEVGLFANASKSFKPNGGTDMAGKAFDPEEGRGYEAGVKLDLLDGRLGMTLAAFHLKKKNVLTADPSNPGYQQTAGEARSQGFDLQFSGQLTEQLRLIGAYAYIDAEVTKDENIARGSRLLNVPKHSGSLMGVYEFREGWLHGADAGAAVNYVGERAGDSSDSGFELPAYTTVDLLARYPLASNATLGVNVNNLFDRRYYERSYNNVWVAPGEPRNLTMSLTLNY
The following text describes a protein:
Function:
Acts as a decapping enzyme capable of hydrolyzing monomethylated capped RNAs (in vitro). Hydrolyzes monomethylated capped RNA after alpha and beta phosphates to form N(7)-methyl-GDP. Shows low activity towards unmethylated capped RNA.
Sequence:
MITFVENKNSSVDNINTNNNNSSSNNNNNNNNNNSRSLFRNLIILLFLLTFLNLILLKKIDLNYKDSDIFYSNNNNNNNKGTTQKFNIDSLGIKLTNLDNLHNTANSIVINKMDKTTQTTTSQSLNDNDNINKNVMNKRVYWPNVYQRISNNNNNNNNNNNNYNNDENDDNSNNNNYVEKIEWNKCILSLMGIDSINKSIGYSFIELDIEDGKLILTSDTNQDEPRVNSGGDEPTTTTTTSSSSSSSDFFTSSINRKRVIMAHAKSCPFHELELSNSIIHKDLQIEKFYPPVKVGVSVLVEDSYNRILLTKRSESLRIFPGIWVLPGGHMEIGENFIQTGLRELNEETGITIDMIDTKTLQVIGIFESSYPNLLPVDKLPIDHHIVVFIYVKLALPTNNNNNNNNKVIIKLQESEVQLAAWTPKSLLLKLLEGTHPEFDLYPTDTYHHQSHKNTLNSASFAPTKDIELILPIGKENDPHYQDLTNDKIKDIFFKGTDNIATGTIYILKQYLREEEEEELLKNNK
The following text describes a protein:
Function:
Final heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading.
Subcellular Localization:
Secreted.
Sequence:
MCNSVRTALAASNCCSIVLCCVLLLTLTLTVAVTAQHNQADETCETLPSEIHLIKEEYDELGRLYRTCNGDVTVNKCEGKCNSQVQPSVITATGFLKECYCCRESFLRERQLQLTHCYDPDGVRMTDHESATMEIRLKEPVDCKCFKCGEMVR
The following text describes a protein:
Function:
Binds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with arachidonyl-CoA, barely with oleoyl-CoA, but not with palmitoyl-CoA.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MEVFLEMLLTAVVALLFSFLLAKLVSVATVENDLSSDQPLKPEIGVGVTEDVRFGMKMDARVLESQRNFQVVDENVELVDRFLSEEADRVYEVDEAVTGNAKICGDREAESSAAASSENYVIAEEVILVRGQDEQSDSAEAESISSVSPENVVAEEIKSQGQEEVTELGRSGCVENEESGGDVLVAESEEVRVEKSSNMVEESDAEAENEEKTELTIEEDDDWEGIERSELEKAFAAAVNLLEESGKAEEIGAEAKMELFGLHKIATEGSCREAQPMAVMISARAKWNAWQKLGNMSQEEAMEQYLALVSKEIPGLTKAGHTVGKMSEMETSVGLPPNSGSLEDPTNLVTTGVDESSKNGIP
The following text describes a protein:
Function:
May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity). Has a role in one of the several mechanisms underlying dendritic localization of Shal channels.
Subcellular Localization:
Golgi apparatus, cis-Golgi network. Cell projection, dendrite. Perikaryon.
Sequence:
MQIKPIITYSGSCPLFRSLESQILNAIPLDTCEWRRTFQRPTKHVRLEAQAQQFNVAALEKYKQGDWSILEHPILHIFVTECNDVDTYKATIREAIDIWLKTLTSYGVSDWMILLVETLDMRKTKNFMPRTTVLDKIRLDFGTKNDDRCISVLNPAKFEQKSTESFRCLVQRIRFLMLTSYNRNIVKYEELIRSKREKRNIEGWDFRQYFFMQEDLALIFEKLELPTEALIQYDELDAMFSQFITHTGLNEKQQWLNHFRKPLDAFHGICLTRADKFEMRNKIRDEGVSLLEFRNYLFERQAYLLLTCNDIPEIAKRLLNFLFSTLREVELIKLECQEGALCCWEFVCALEVLQLCEQAMEPNELTCFQHCAPIWNLAKDKLYELGKLCGLLPGCTPTSEQLHIVVQLSSGIGDAPSEQHQFLQATPQLRDRSPNRKPKKSGAEQLKEALGSNQAFQKLYLELAELAISTYKHVTRLRSARLVGLDLGNFYCALNEPHKAVGFFTDLLRELKAENWHMLSSQTLLELANCYRKMGDSLAYTKTCSSISCCAELETLVRTFYFDEFLKSLKTLKTTLSAQPSIENANYCVLEDHFRILDIEVVNQKPIIQDDYILVQLKVESLYPRGVVAENVKLCYELEASSLELAMENVSLTASPSTVKAKDTSSRLKVSLQLVYKQDNRLHSAAVACDLPKSKQPVRRTSSTKRKLSPSVQADFTNFVQAENIALQPGVNLIEMKAKATRVGCWQFKQLCISMSSLEFLSEQLPFMPATFEISTKPASATLEFKTLIAGIVQPISLNVSGGSFIFPPDAKITLRCSKNLRIRQARNTDDEAAYNDDQSFESTLQVPLVQFKSFEERRIPLEVLTDMPGRKVSKHHEHHIALNCPWSRTELPIAVDFQPAMEATCRLHTCGTQKFLQVIMKGMEAHLLLQHAQVKCDVPGVQLLDLNPESQQPIEIYKSLTVTYLYEIQVEPLKTEHELPVVKVHFVIKYASLSQPDVWRTYGCAFDLVDYTTLFKLQAQLEPNELCRLRTVCNMNLKITKVHENPYTDLMYEVLNDQNLWAVCGRSAGVVSMKDVDSHSISLDVMPLSTGFLPMPSIRLSKYTAGGKSKTDGHSKVHPFPPGQVYNSTKSMQIHVIASVAGDQ
The following text describes a protein:
Function:
Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.
Subcellular Localization:
Nucleus.
Sequence:
MGKRKAAAKPPPRKRMDKLDTVFSCPFCNHGSSVECRIDLKNLIGEANCQICQESFSTTANALTEAIDVYSEWIDECERVNTVEDDDGA
The following text describes a protein:
Function:
Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity).
Miscellaneous:
MISCELLANEOUS: The N- and C-terminal domains are separated by a 2-repeat G-Q region.
Subcellular Localization:
Nucleus.
Sequence:
MAQPLCPPLSESWMLSAAWGPTRRPPPSDKDCGRSLVSSPDSWGSTPADSPVASPARPGTLRDPRAPSVGRRGARSSRLGSGQRQSASEREKLRMRTLARALHELRRFLPPSVAPAGQSLTKIETLRLAIRYIGHLSAVLGLSEESLQRRCRQRGDAGSPRGCPLCPDDCPAQMQTRTQAEGQGQGRGLGLVSAVRAGASWGSPPACPGARAAPEPRDPPALFAEAACPEGQAMEPSPPSPLLPGDVLALLETWMPLSPLEWLPEEPK
The following text describes a protein:
Function:
Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Sequence:
MSRTLASAVPLSSPDYYERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLRSKDSLGLKEELTDEDREKVAVQEGINSGTAMSRGLYQPATIFMGRQMSAISSMGDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKTPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSRSEGSEGEILTREHIEVEEKRASPPVSPISVSEYCESENKWSQEKHSPWEGVSDHLAHGEPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQAPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEECGHRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAAAIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD
The following text describes a protein:
Function:
May be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNVAYAQGVV