lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.
Sequence:
MDNKGSPPTHSISLPEQIITFELSSYEWSQNLVCIALMDKLILGSVRFPEESENECFEWNQLKEIHHKSRPHSVAFAPETSLAVVPKKVVLASAGSDYKIRIFQSDLDQSDTVQLLEGHSSYVNHVSWDPDGEFLASCSDDNSCVLWKCKEDYSQGPSFFFGSAVQSAKWHPEESGHLLIAEKCGAIHLYKVHMKTSMLSVETDTNPLSYADWSLANAAYVAAMARGCIFSWDLKNASWPIENKPMHDECGHIVKFSPHSESVVASIGRPNATLKVIHLKNKLPQIEAKLLLYGGLCWHYQLPYVVAASDRKLCFWKVSI
The following text describes a protein:
Function:
Receptor kinase that detects X.oryzae pv. oryzae protein Ax21 to promote innate immunity. Following X.oryzae pv. oryzae protein Ax21 detection, undergoes cleavage, releasing the processed protein kinase Xa21 chain; The processed protein kinase Xa21 chain released by protein cleavage after X.oryzae pv. oryzae protein Ax21 detection translocates into the nucleus where it can bind and regulate WRKY62, a transcription factor. Confers resistance to the bacterial pathogen X.oryzae pv. oryzae (Xoo).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MAPQVFRTQPLIPPSYQSLFLLCTILIFLSSNTIIFSSAQATNKTEDDRQALLCFKAGISKDPAGVLGSWSNDSLNFCSWRGVNCSTTLPIRVVSLQFRSAQLTGTLSSCTAALTSLVQLNLWNNKLSGSVPEEIGELRSLQTLMLAANRLSGNIPLSLGTAASLRYVNLANNSLSGAIPDSLANSSSLSEIILSRNNISGVIPANLFNSSKLVAVDLRSNALSGAIPHFQKMSALQFLDLTGNSLSGTIPASLGNASSLRSLLLAQNKLARSIPETVGQIPNLKRVDLSNNMFSGYVPATLYNASSLTFFRLGSNRFTGQLPSDIGHSLPNLETLAMGLNGFRGSVPDSLTNMSKLRVLDLSSNSLTGVVPSLGSLANLSVLLLGDNKLEADDWAFLTSLTNCTQLLILSADGNILNGSLPKAVGKLSTKLQRLSFGRNQISGDIPAETGKLVSLTLLDMGQNMLSGPIPLTVWNLRNLVVLKLSMNRLSGQIPSTVGNLVQLSQLHLDDNELSGNIPANIGQCNRLLMLNMSVNHLDGSIPRELFSISSLSLGLDLSNNNLTGPIPWEVSNLINLGLLNVSNNKLSGSLPSELGLCVQLLSLQIKSNMLNGSIPEYFSKLKVIQQIDLSENNLTGQVPQYFVNFSSLNYINISYNKFEGPIPTGGIFRNSAVVFLQGNTGLCETAAAIFGLHICPTSSATRRKINTRLLLIVAPPITIAVFSLLCVVVTIMKGTKAQPSESFKETMRRVSYGDILKATNWFSLVNRISSSHTASVYIGRFEFETDLVAIKVFHLSEQGSRNSFFTECEVLKHTRHRNLVQAITLCSTVDSEGEEFKAIVYEFMANGSLDMWIHPRVGSSRRLLSLGQRIRIAADVASALDYMHNQLTPPLIHCDLKPSNVLLDYDMTSRICDFGSAQFLSSSIGRPEGFIGVGGTIGYIAPEYGMGCKVSTGGDVYGFGVLLLEMLTARRPTDVLCGNALSLHKYVDRAFPERIAEVIDPHMPSEEDEAAASVRMQNYIIPLVSIGLMCTMESPKDRPGMHDVCAKIVAIKEAFVETL
The following text describes a protein:
Function:
Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA.
Subcellular Localization:
Nucleus.
Sequence:
MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGSSGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPTSKRESNSRSRSKSPPKSPEEEGAVSS
The following text describes a protein:
Function:
Negative regulator of epidermal growth factor receptor (EGFR) signaling.
Subcellular Localization:
Membrane.
Sequence:
MDTTDQPNSICHVQPIQMYPLPPSEPSVSLPFKLLAGEAIFHHGKTVDGLIVLTNYRLYLQLGDNHYHLPLGLIESVEHRELFYLHIGCKDARTYRCIFGNNESCMEWFERISKAAEPPRQLEQIFAFYHFIWAKDKGGDEIDDKIRNLKRYTFDYKLFKEEMERLQFEGDSWRISDANKNYKLCPTYPPYLIVPSCINDETLECVAKFRSSRRIPAVVWRHTKNGAVIARCSQPEVGWLGWRSSEDEDLIKAISQACNFDQRNDKESILSHSPGSLHSEDSLQITTDLSTKEKKVLIMDARSYTTAVANRARGGGCECPEYYPNCEIQFMNLANIHSIRKSFNALRLLCTASADQPNWFSQLEGTRWLQHMSGLMKAAVTLVNAVEREARPVLVHCSDGWDRTPQIVALAELLLDPHYRTMDGFRILIEREWLAFGHKFADRCGHSSNDDPNERCPVFLQWLDCVHQLLLQFSCAFEFSQSYLVKLAQHVYSNIYGTFLCNTFQERMKIVNGKTFSVWEFLNSPRFKNHLYASPGNSCGNKVLWPQCNVRDLQLWREVYLGSWESNFSTDGGSGSCPGPPESSPSHMTKTRSYGDLLNAADVCSNQFRRSSDPSINIDKKLLMSQETATQDIVNGHSKQGDFLCNDTDEVECNKDCIYKDDKPKFQIRNGSAGGVRDGDFLRDHVINGDKTDTSDECEDEVRGGVCLHEFLTPSLSHNNCNEVDSDNELTEKSESKSENTVCEKLETSTDTLVSDNHNISSSPLEVNGFEKLQSPEEGADLPDGYNKLSAQLSLVNECHREAAKYCISPLYSRTSSSSGWDSGLSPHKPWHQTHPYSLGDDGLIPVTSVAQERLWQIIQEHKRKEELLEKELHTYRQALLKQSCHRCNNNDSEKLDDASSVVESVCSAGEGQASAVESLRSDMSWEALEENSILTECTTTLWVPDHAVSRCTGCQTEFWVGKRKHHCRKCGRIFCASCSENSTPLPSEQLYNPVRVCTGCYSKLRRDCGELPDQCKHSNPQPTNSNPQITASSN
The following text describes a protein:
Function:
Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSEADDTIAAIASPMTPAPRGIVRLSGHDCIDVLCRMKVLDTDEASGRRPFRSSKTLSLGEPLGAIEVDVMVWPTQRSYTGQPSAELHLIGSAPLLQSSLDAAIRAGARAARPGEFTMRSFLAGRLDLTQAEAVLGVIEAEDRGTLDQALSQLAGNLSRPLQAARSTLLDLLADVEAGLDFVDEDIEFISDEALIQRLDELRSLLLQTRSQLSDRGGASSTIRVVLRGLPNAGKSRLLNVLSRTESAIVTDQAGTTRDLVTVESSWGGHSFQLIDTAGSESREESDPEAPISQEAQLQAAEAARGADVHVWCIDATGGDGFESLKSPNAVLAEAKRSAQLICVATKRDLMPTDWNGESMRADLAVSSESGTGVDSLIERLVQFAEQRDAGETGSVIGTAARCQDSLAAAIEHLAQAIQWTEQAAGHELVAAEMRLAVEAIGEVTGQVYTDDILDRVFGRFCIGK
The following text describes a protein:
Function:
Non-catalytic component of the polycomb repressive deubiquitinase (PR-DUB) complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK118ub1). Important for maintaining stability of the PR-DUB complex. Probable epigenetic regulator involved in developmental pattern formation and eye development.
Miscellaneous:
MISCELLANEOUS: Named 'six-banded' due to its distinctive embryonic expression pattern.
Sequence:
MAAASAGQQQQQHQHQHKLNIAGSAETVVSGMQHQQQHQQQHQQINMFKQQQQMLPLQQQHHQFFQQQQTKFVSRVVTSAAVHQQQQQHHHQQQQQQQHQQQQQILPAGLVNGNGSGNMMQVANLHLQQQQQQRNSQQHIFVCPTSNQQLLLQQQQQQQQQQQQQQTKQRQAQIKLPIKSAATTGVTAATVAAATAATGATHCMSTTIAARQMSQNNQLYAKNVAKANNASSNGNINRKTATSYNGNLAPGWRRLTNNNEVAYISPSGKTLRTQFQIKDYLLTQGTCKCGLPCPLRPEYLFDFNAQVPNQPLKLPTEASTATPTPCRHQRRFLESQQLQLPQQQQQQQHLQHQQQQQQAVKDVSVDVAVSVSGPAAVSDVFSTLMTSTARTATMVTPTAATSPAQAATTTTHEMANKDADCHKYGNNKLPATNRTATTPTPAPTPPPQHPNGMPTSQALALGGVPVGVHPKRPTGGHVIKQPASVLGPPCTPPLAVGGANTVIQQQQPLQQHPNFKDDPAGYLQQQTALLHNSLGVGLDATKTAAGTSTARALPQEPIVHSSQQQQQQQQQQLQQQQQLQRQKIRRLSLFGKWETDPAPATNSQPTNGTRALQVDAAAFARPQKPQVTCVTLVPPPQESPVSSSAAETLEKRPEQVGAISTSHESPRQSLSSPTDSVDSAKSTPSASPKPQTQVPMQPQLLQMRPHLQANLSAQTPVTVPAHVRVMRQQQAQIIPGQRLPVASSSAAMATMTRSIVTSTAGTSTITGRPVATTLNNSNPTVAQLQSMANAMNGAGGGGQLIMTSSGQLLVIPTPSKQTTQHHRPGQPGQGVIIQQQQPAELHPQPGGGYIVSQPSPVAAASSSSSSSTVILNSGGAKLLHHQIITSQAGQINQATSGGSGNQPQTVLLNTLPNGGYIVQQQPQTQSPQQAEQILAMPQPPPAQTLIISSPDTKRRARKRKSSVCHTPPPSGSPAKIISPQISPSIPNQAPALLHQQAAAAAAAAPQFQQQFQLSPGIQGIVVNKPNPPQQPQTQQLLLQNGQILQQVNLIGQQLLMPAGLVMGPDATLLQIQNMPATSLMTPQGPVMLRTPSPQNKPSFISPSAGGQQYLVGANGQLSPIGQIYSTPMGLVMPTGQQGGASFVQASPTTTTIQIQQQPAPQPTQISLQPAQATYMTETVMSRQGTAASPPDTTTCSPRSPERPSSHRSSGSDMVQCVSSSEPDAAVSPQSTESRQSPSSTDCERSICKNNVFTQPSGIYKHSEPKIRRIHITSQTSAENGISLMQGQESPTTTQLLSSVPTAQPTVEKTTVRTPTKRSRRPQRGAARAAPSASDKSFPLPPRSFAIGELIWGPARGHPAWPGKIVKMPDGVCTPSQQFDHVWVQWFGGGGRSTSELIPVNSLQSLSEGLEAHHKAQKDTRKSRKLNSQLERAIQEAMTELDNISASSTPAATSSSSATISAVPASAGPAVIGGQQQYQQQQQQQQQQQSPSSTNNKINGLARSKRQANTSGASMVLTTSTAATLSGLFNQQRAKPIRIAPAPPVATTGTGNIGTIAAAGAAAASTGTGTATTSARSEILKLAK
The following text describes a protein:
Function:
May have a role in the transport of dicarboxylates from the periplasm across the inner membrane. Seems not to be essential for growth. It is likely to be a cryptic gene, as no or low expression has been found under a number of growth conditions and when tested with a large number of potential substrates.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MFGIIISVIVLITMGYLILKNYKPQVVLAAAGIFLMMCGVWLGFGGVLDPTKSSGYLIVDIYNEILRMLSNRIAGLGLSIMAVGGYARYMERIGASRAMVSLLSRPLKLIRSPYIILSATYVIGQIMAQFITSASGLGMLLMVTLFPTLVSLGVSRLSAVAVIATTMSIEWGILETNSIFAAQVAGMKIATYFFHYQLPVASCVIISVAISHFFVQRAFDKKDKNINHEQAEQKALDNVPPLYYAILPVMPLILMLGSLFLAHVGLMQSELHLVVVMLLSLTVTMFVEFFRKHNLRETMDDVQAFFDGMGTQFANVVTLVVAGEIFAKGLTTIGTVDAVIRGAEHSGLGGIGVMIIMALVIAICAIVMGSGNAPFMSFASLIPNIAAGLHVPAVVMIMPMHFATTLARAVSPITAVVVVTSGIAGVSPFAVVKRTAIPMAVGFVVNMIATITLFY
The following text describes a protein:
Function:
The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MLLAVLFSNSEGNILIERFHGVPAEERLHWRTFLVKLGADNLKGAKSEELFVASHKSVYIVYTMLGDVCIYVVGKDEYDELALAEVIFVITSSVKDVCGKPPTERLFLDKYGKICLCLDEIVWKGMLENTDKDRIRRLIRLKPPTDI
The following text describes a protein:
Function:
Lipolytic acyl hydrolase (LAH).
Domain:
The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
Sequence:
MAAFLRIAPIPNIPTKPSPPYSMNIRWSSNFSPSSLIIRSSNRQHKTCSISRPSPPSLLIASSNRPFSLLSIDGGGVRGAIPATILLTLENELQKLDGPDARLASYFDCIAGTNSGGVIASLLALPNLMGNPMFEAKDLQNFFVDYSESMFKPRNLLVQIGMKVKSLISGSPYNSWDLENVLSKHMGSTTLGEACTNLIIPYTDMKTRGQLTSFTTYQETDLNTKLIDVCLSTTSGYPTEKNPLGGALHEINLSGDRRIPSPWVPSLILSLGTGIVSLHGRGVFTPETLREKKWAKINRHKRWSTAMYSSIVSEYVGYDVQQSLGPKDFYLRIQDYRPDLINMDDNLASLDNSTRMESLVEAAVRLLQETNASGLPYLPYNKMGLPYLPYNKIVDEETTNETLLRNFANLLSEQKKIREGGN
The following text describes a protein:
Function:
Photoreceptor required for image-forming vision at low light intensity. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Signaling mediates the activation of phospholipase C (By similarity). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
Subcellular Localization:
Cell projection, rhabdomere membrane; Multi-pass membrane protein.
Sequence:
MGRDIPDNETWWYNPYMDIHPHWKQFDQVPAAVYYSLGIFIAICGIIGCVGNGVVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFMKYWVFGNAACKVYGLIGGIFGLMSIMTMTMISIDRYNVIGRPMSASKKMSHRKAFIMIIFVWIWSTIWAIGPIFGWGAYTLEGVLCNCSFDYITRDTTTRSNILCMYIFAFMCPIVVIFFCYFNIVMSVSNHEKEMAAMAKRLNAKELRKAQAGANAEMKLAKISIVIVTQFLLSWSPYAVVALLAQFGPIEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFRERIASNFPWILTCCQYDEKEIEDDKDAEAEIPAGEQSGGETADAAQMKEMMAMMQKMQAQQQQQPAYPPQGYPPQGYPPPPPQGYPPQGYPPQGYPPQGYPPPPQGPPPQGPPPQAAPPQGVDNQAYQA
The following text describes a protein:
Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
MSLTVHPDLNTSAWPGPSTNVSGQPAVRVTRLSPAQQVLVVMVTASLSVVTVLGNLLVILSIKVNSRLRTVNNYFLLSLAAADLIVGLLSMNLYTLYRVRGQWPLGAALCDTWLVLDYAVSSASVMNLLLISLDRYLCMTRLQSYSAWRTRKMAGLMIGAAWVLSFVLWAPAILCWQSAGSRRVVPEGHCYIQLLVSPAVTLGTSLPSFYLPALTMIVLYGRLSAASHARLSALQVERATPSTPTDGPVVDEDSTNNQTDLLSRKDLHWRASEALSTFRCQEGRRQRVMARERRVTKTILAILLAFILTWTPYNIMAVVAAFCHICIPDVVWSLGYWLCYVNSAINPGCYALCNTTFRRTFCSLLHLENAQNVRNASV
The following text describes a protein:
Function:
Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2), ccatalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity (By similarity). Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (By similarity). Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs). Exhibits high N-acyltransferase activity and low phospholipase A1/2 activity (By similarity). Required for complete organelle rupture and degradation that occur during eye lens terminal differentiation, when fiber cells that compose the lens degrade all membrane-bound organelles in order to provide lens with transparency to allow the passage of light. Organelle membrane degradation is probably catalyzed by the phospholipase activity (By similarity). Plays a role in phospholipid metabolism and adipogenesis.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Cytoplasm. Cytoplasm, cytosol. Cytoplasm, perinuclear region. Peroxisome membrane. Mitochondrion membrane; Single-pass membrane protein. Nucleus envelope. Lysosome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Note=During eye lens differentiation, recruited from the cytosol to various organelles, including mitochondria, endoplasmic reticulum, nuclear envelope and lysosomes, immediately before organelle degradation. This translocation is triggered by organelle membrane damage and requires the C-terminal transmembrane domain.
Domain:
The C-terminal transmembrane domain is required for the targeting of the protein to damaged organelles.
Sequence:
MPIPEPKPGDLIEIFRPMYSHWAIYVGDGYVIHLAPPSEIPGAGAASIMSALTDKAIVKKELLRDVAGKDKYQVNNKHDKEYTPLPLNKIIQRAEELVGQEVLYRLTSENCEHFVNELRYGVPRSDQVRDAVKVATVTGVGLAALGLIGVMLSRNKKQKQ
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Sequence:
MESRCKKGYFRLAVIGLSKAKDCWEKNACAVTFIGDGGTSEGDFHAGLNFAAVMEAPVVFICRNNGWAISTHISEQFRSDGIVVKGQAYGIRSIRVDGNDALAVYSAVCSAREMAVTEQRPVLIEMMIYRVGHHSTSDDSTKYRAADEIQYWKMSRNSVNRFRKSVEDNGWWSEEDESKLRSNARKQLLQAIQAAEKWEKQPLTELFNDVYDVKPKNLEEEELGLKELIEKQPQDYMMLKELIPNWILGIGTLALRYDFQETLFNGWHAIAELQQLKLKIKLNSLLNDQADTESLKAARNSALNVIQAMIIHLVLTLKGRFSLPLTEETVRFNEPIQLNQNMVKDGGYTAELFPIRKEEQGEVRR
The following text describes a protein:
Function:
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
Sequence:
MSETSITDSVETKIGLDDPALLINRELSWLEFNSRVLDEALDERNPLLERLKFLAIFSSNLDEFFMVRVSGLKQQVELGLTNKTPDGLGPQAQLDAIAHRLRPLLETQTMALRTQILPRLAEEGIRICDYGEIKILPRQQERLQRYFEEQVFPVLTPLAVDPGHPFPYISNLSLSLAVLVRDPVSRKELFARVKVPQGLPRLVPLGIPNQFVSLEEVIGAHLDQLFPGMEVLSRHPFRLTRNSDLEMAEEEAEDLLLTIEQSVRNRRFGEAVRLEITPQMPVHVRARLLEELELDEQDVYEINGLLDLRCLWQLAGLERPDLKHRPFSAQVPPDFRNPQLDIFQLIRQGDRLVHHPYDSFAATVERFVSAAADDPDVLTIKQTLYRTSGDSPIVRALIRAAENGKQVAVLVELKARFDEENNINWARALERAGVHVVYGLVGLKTHAKALLVVRREKGHIRRYVHLATGNYNSKTANLYTDYGLFSCRPDLGADVTDLFNYLTGYSHQTHYRKLLVAPARMRDQFVELIDREIAARSPEAPGRIIAKMNSLVDPILIRALCRASQAGVHIDLIVRGICCLRPGYAEVSENIRVISIVGRLLEHSRVFYFGNAGNSEVYIGSADWMPRNLDRRVEVMTPVEEPRLREELVAFLNLLLSDNRQSWELQTNGAYARRQALPGEIEISSQQVLIDRALSR
The following text describes a protein:
Function:
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSRAKKQ
The following text describes a protein:
Function:
Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Nucleus and/or cytoplasm.
Sequence:
MFIPQNKSKRLSLDKIGQLEEDLELNPLDYNKWQKLIDQLIIKDNQEQVRNTFDKYLKIFKFDGASWCKYIKYELNRDEKEKVENLFQQCLGITDNVELCRLYVDYVRGVTDFVTGGEKARGVVVQAFEFAINKVGIDITSESLWQDYIQFLQSWNPNANWEQQQKIDLIRKVYKKFLTIPTENIEVSWSQYTKWENELNPATASKFISEKSGEFMLARSWNTEFNRITDKSLKRNLNPGDHNDEDVVKQLKYWLRWLELEKENKLELKDETVNDKRIQYVYKQATYALPFVPEIWFQYVKYLLVQNEEGNLQESIRLLKEGGLVLNPKSMLLTFQLAELYERDNSFNNAKIVFKNLLDALQKDYNSVANQIAELKERIDPATDKDNIQEDDDDNEEEEEEENDNDNDNDNGGDSKQQPPSKKLKLNPNGGQNGSNSENNGEAVSAPSSSVKLPQVYRISLADSKQLLSFENEQKRLSDAITLTYVKFMIASKRSEGIKEARNVFKQARKFTDIGYQIFIESALLEHYSDKKSTALKIFDLGKKNFATNGKFLLNYLDYLIMINDVDTMRTVIQSSDANFTKEIGNLQEELKLTNLDPITRKKLEKQITNLKKFLKQLYKKYISFAATFLSLDVTHSFAKKCEQLFPKDDPIDLFTDRYKLDNINIIKKDELGRDDILTSFDGIIDEEELQRLKRRKLSNGSGSSSSYSFNEEESKSAIKNIEEQKTRVQQEQDQENQGINKPEESFVGPSIIALMSALPNASYFGLPSESVFNSEKLVTLFANLSNIPSQ
The following text describes a protein:
Function:
Negatively regulates antiviral innate immune responses. Disrupts the interaction of antiviral protein MAVS with innate immune receptor RIGI and inhibits MAVS aggregation, resulting in the repression of type I interferon signaling and innate immune responses (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Mitochondrion membrane; Single-pass type I membrane protein.
Sequence:
MNSVSTQLILVLASLLLILPVVEAVEAGDAIALLLGVVLSITGICACLGIYARKRNGQM
The following text describes a protein:
Function:
Vacuolar Fe(2+) uptake transporter.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MSVSRLEIHTPPPELIMAAGAEIKLSVNSNNNNNNNNNNNNNNNNNNNNTEDEEEKRVNLIQRAQWLRAAILGANDGLLSTTSLMLGVGGAKEDERLMIISGLAGAIAGAFSMAVGEFVSVSTQRDIEHATTTTTTTDIHKCINDNDKSIKPREISMPVDHEPSTDTQTNNPLLPNPYKAAGASGLAFLCGSLVPLLSGMLIPGYKTRAVGIVLVTSVALVIFGGAGARLGGRSSVRISALRVLFGGWISMAFTYGFLKALDTDRKGHDSD
The following text describes a protein:
Function:
Essential component of TORC2, which regulates cell cycle-dependent polarization of the actin-cytoskeleton and cell wall integrity. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway. TSC11 may exert its functions through two distinct mechanisms, one mediated by AVO1 and the other mediated by AVO2 and SLM1.
Miscellaneous:
MISCELLANEOUS: Present with 1840 molecules/cell in log phase SD medium.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSIPHSAKQSSPLSSRRRSVTNTTPLLTPRHSRDNSSTQISSAKNITSSSPSTITNESSKRNKQNLVLSTSFISTKRLENSAPSPTSPLMARRTRSTMTKALLNLKAEINNQYQELARLRKKKDDIEHLRDSTISDIYSGSYSTNHLQKHSMRIRANTQLREIDNSIKRVEKHIFDLKQQFDKKRQRSLTTSSSIKADVGSIRNDDGQNNDSEELGDHDSLTDQVTLDDEYLTTPTSGTERNSQQNLNRNSTVNSRNNENHSTLSIPDLDGSNKVNLTGDTEKDLGDLENENQIFTSTTTEAATWLVSDYMQSFQEKNVNPDFIAQKANGLVTLLKEHSEIRKDLVLTSFMSSIQNLLLNGNKLIAASAYRVCRYLINSSIFIDELLELRLDAFIIISLAKDNSFQIEREQALKMVRRFIEYNNGVTQGIMQAIISCVEKPEDSLRHMALETLLELCFVAPEMVKECRGMRVIEGFLQDYTSFSLASVILDTILQLMATHKTRQHFLEDFNVSVLTTVFSDTNTKSNVNVEKMQNASTLISITLNSYNGFMLFSNNNFKPLKQLVSFFQIPICAQYLIDIFLDVLKIKPLPYKPRGRHSHSFKPIPSQYYKECMSVNQRLALIVLILENSEFVPHLLELLNEEDRDDHLVAKGRYLLTEYFNLRMNLVDKKYTSVSKPIYKENFTYVNETFQFKKIAYKMNRNRNTIGMSGIDYAQNIKSFSKNIKENTLLREVDDFRFRRMVYDSKVLQTKDFTRWNWNIINELLEGPLLNKKQLEELVKSTKFIRRLLVFYRPLRLRFSNVNKGAKLSQKYVQVGCQFFKTLTATPEGMKILMDDTKIIPQLASLMFRAMEGNISGNIFNKNKLREKIIFGYFKFIGILTQSKNGVHILTRWNFFTVIYKMFQFESKLGLEFLLLTIPELDLKYSSHCRVIIGKALVVANEKVRIEATKHIGDKLKELLSTKESDLKLKANKVKLQQFKMEMLTRQLYDLSPSVVAVADQALYECIVAGNGSEELGTSFRMFLNQMVFIRSPILFELLSRPYGFQLLNEINFVKEERDSWLSKKNIEYVHIVEEFLKKNESINAKSLTFQQKSRLPLHFYESLTKTEDGILLLSQTGDLVTFMNVIKKYVNGNNMATVENAKEILDLKAALWCVGFIGSTELGIGLLDNYSLVEDIIEVAYNASVTSVRFTAFYVLGLISMTREGCEILDEMGWNCCVSVQDEPIGIALPNRLDRFLSYNEHKWSAFGEYSDEMIVFNKSDGDLIEKCLPIEFDLDKLLKEKDTAENPLNEKIITNKYDNDITSQTITVSGENSSLFANEGLSSPYVTQYRNDDDSIESKVLHIVSQLGNHILSNHAVKEITEINNKYGPRLFENEKMFFKVFNMMSKYRFKPHVRKFLCGLFINNRALENVIRHDNKRDKRPANFTR
The following text describes a protein:
Function:
Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter (By similarity).
Miscellaneous:
MISCELLANEOUS: Binding is severely inhibited by complete or partial cytosine-specific DNA methylation of the binding motif.
Subcellular Localization:
Nucleus.
Sequence:
MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSPAQTEKASVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLSSQDC
The following text describes a protein:
Function:
Commits homoserine to the threonine biosynthesis pathway by catalyzing its O-phosphorylation.
Sequence:
MSVISFKIKVPASSANIGPGFDVLGIGLQLYLTITVTIDPSIDTSSDPHHALLSYEGDGKVPFESNENLITQTALYVMRCNGIKDFPRGTHIHVNNPIPLGRGLGSSASAIVAGVYLGNEIGNLKLDKYRLLDYCLMIERHPDNIAAAMLGGFIGSYLNELSSEDSQLTTVPLDYILPKVKNGELITPQDKIVSQQPPNNIGQYVEYKWNKKIKCLTIIPNFELSTDLSRSVLPKNYQLPDIVYNLQRIAILTTALTQDPPNHKVIYQSMKDKLHQPYRFGLIPGLNTVLQKITPESYPGLCGICLSGAGPTILCLATDGFEKIANDVIEIFKQEGIECDSKLLDLAYDGATVEYGS
The following text describes a protein:
Function:
Plays a role in the regulation of cell morphology and cytoskeletal organization.
Sequence:
MAEREVETGPRKRFEQKSDAVFDEIVENCGVMDTEMSEDTDHNLTPTLASMSYGMPNQTGSENSLLDEDDYFLNSGDLAGIPVVSSDNEDEQDCSSKDNLVSSVHTDGSLEVERRAAHQESDNENEIQIQNQLKKDFPKQFDQVSVFKSIRKDFCLVRENSKETFSGKEKNRDLTYHEREKRLDKPHKGLDSRLKSSFFDKAANQVEETLHTHLPQNPETNFRDSSYPFASKESIGSELGNSFASNIRIKEEPLDDEYDRAVAPQQGLLDRVKDEPDNAQEYSHGQQQKTQEGELKISAVFSVSGSPLAPQLTTGFQPSLASPGMNKMLPSVPATAVRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPPARPPPPLTKKTCSSCSKDILNPKDVISAQFENSTTSKDFCSQSCLSTYELKKKPIVTINTNSISTKCSMCQKNAVIRHEVNYQNVVHKLCSDACFSKFRSANNLTMNCCENCGGYCYSGSGQCHVLQIEGQSKKFCSSMCVTSYKQKSAKITPCALCKSLRSSAEMIENTNSLGKTELFCSVNCLSAYRVKMVTSAGVQVQCNSCKTSAIPQYHLAMSDGSIRNFCSYSCVVAFQNLFNKPTGMNSSVVPLSQGQVIVSIPTGSSASAGGGSTPAVSPTSINSSAAAGLQRLAAQSQHVGFARSVVKLRCQHCNRLFATKPELLDYKGKMFQFCGKNCCDEYKKINNVMAMCEYCKIEKIIKETVRFSGADKSFCSEGCKLLYKHDLGKRWGSHCKMCSYCLQTSPKLIQNNLGGKVEDFCCEECMSKYTVLFYQMAKCDGCKRQGKLSESLKWRGDIKHFCNLLCILMFCHQQTVCDPPLQNNAVASISMVQAASAGPPSLRKDSTPVIANVVSLASAPAAQPTANTNSVLQGAVPTVTAKIIGDASTQTDALKLPPSQPPRLLKNKALLCKPITQTKATSCKPHTQNKECQTDTPSEPQVMVVPVPVPVFVPIPLHLYTQYTPVPFGIPVPMPVPMFIPSSMDNDEKATEGIEDIKEKLATHPFEADLLEMAEMIAEDEEKEKTLSQGESQTSEQELFLDTKIFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALKSNAVQDADSELKPFSKGETEQDLEADFPSESFDPLNKGQGIQARSRTRRRHRDGFPQPRRRGRKKSVVPVEPRSLIQGALQGCSVSGMTLKYMYGVNAWKNWVQWKNAKDEQGDLKCGGGELASASPCSDSLGSAQDHALSQESSEQGCKARSVKLKEDILSCTFSELSLGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPYSRFMIELTKLLKIWEPTILPNGYMFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLRNVTEHLKLSFAHVMRRTRTLKYSTKMTYLRFFPPLQKPESEPDKVTIGKRKRNEDDEAPVGVEMAENTDNPLRCPVRLYEFYLSKCSESVKQRSDVFYLQPERSCVPNSPMWYSTFPIDPGTLDTMLTRILMVREVHEELAKAKSEDSDAELSD
The following text describes a protein:
Function:
Probably part of the binding-protein-dependent transport system YnjCD. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MATPLRYALIFLLWAMVAVIYAPLIPAALTLISPALSLTHWQALFADPQLPQALLATLVSTTIAAVGALLIALLVIVALWPGPKWQRMCARLPWLLAIPHVAFATSALLLFADGGLLYDYFPYFTPPMDRFGIGLGLTLAVKESAFLLWILAAVLSEKWLLQQVIVLDSLGYSRWQCLNWLLLPSVAPALAMAMLAIVAWSLSVVDVAIILGPGNPPTLAVISWQWLTQGDIDQQTKGALASLLLMLLLAAYVLLSYLLWRSWRRTIPRVDGVRKPATPLLPGNTLAIFLPLTGVLCVVLLAILADQSTINSEALINSLTMGLVATFIALLLLLLWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLKLDGSWTAVVWGHLLWVMPWMLFILQPAWQRIDSRLILIAQTLGWSRAKIFFYVKCPLMLRPVLIAFAVGFAVGIAQYMPTLWLGAGRFPTLTTEAVALSSGGSNGILAAQALWQLLLPLIIFALTALVAKWVGYVRQGLR
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSELHNPDQSSRALFDLCRVLLKGIYGELSAVLVGSLLDYGRQTAAELAKTTKLPLSAVHSGLAALVQNRFVLYWANDRKSGRDTDDIGESSSIHYVANWKEIYQVVRAGGMVDAVRKDFGKGPGGKSNPESGERCAEIAQNLLVYGHMRVADYLEATPEHDRDSVEASIAVMLRKRFLVPVQAWQFKPETDLYARMFRDHLSKLPLSMAESARKNQAAVSAKTELERMQEERNSLNLGFVSGSVARTKGVPVLNRAEKLDHQAVLCANPDKFLVIARNEELAKLAEERCGKTAAEVYRQCLSKYVGRLHSCTQDTSPGAEFNITSMEIAKTIDPRLDGLRPRGKGSRSVSPRPQSKRVKTEEGYTKTGDYDEKEVDVEEDMEEELSGVALATAVSKQMQILAASPLKFVQSVGTKGGGEWYVNFKEATECLRGARYEQIIQWKYGRVAKRLLRAVKDKGKVDEKLLTNIALLPVKEILNHLHDLHSVGALDVQELPRTADRAASRTIFLWHHRANRAYSLISQDIYKSLSRCFERVAAERAKLPILLSKLQREDVKGHEDEFLTEQEKADLKGLRMREEKLLVQMNRLDGLIRVFRDY