lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS
The following text describes a protein:
Function:
Controls stomatal patterning.
Subcellular Localization:
Secreted.
Sequence:
MCGTRRRKLRWLCFFFLYLPLLAMSQGGHGEQLVHAKEDQDARPLRVMNGGGRMGEQRLSRVGSRPPCCACERRCGGCAPCTAVQVRAGAGVQCANYEPIRWTCKCGGAVFDP
The following text describes a protein:
Function:
Transports pantothenate into the cell.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MALLNRLAKTFSPYYGLNKVEQKLLIKIDWFILSYCCVSYFINYLDRSSINNAYLSGMQEDLKMHGNELQDINVVFTCGYIIGQLPGSYALQRVPARLWFSVMNILWGLMTIFSFAVHSVRALMILRFFMAVAEASTFAGTHYILGAWYKESELCKRAGIFSASGLVGTMFAGYLQTAVHSSLNGKGGLSGWRWLFIIDGILTIPLSLYGLFLFPDVPETTKAPYFTEQEKELSFKRLPARPKKKPLTLKAIKDIVRSWRIYGLCILWIFSGETQAIAVNVLMGQWMKWSNKFSVAQINNYPTVITAVGVVSTLGASVISDKLAGNPRWPFGLFLCVITTVSATILLAWNVPDGAKFFAYFASGCTYAGQAVWFSWANDICRDNDQERGVVVFLMNMCQNIWHIWWAPIMYPNTDTPRFIKGLIGLLVVGGIVFVSSCIVSYMQIRDKRIKRSIQDAKDFDDVFTEHESLELKKIGKNDEESLNTTNAVKEISSPGLVITRQRISMPKETNAQD
The following text describes a protein:
Function:
Suppresses host programmed cell death during infection by binding to Z.mays WAK17 isoform 2 and Z.mays LRR5, to prevent activation of Z.mays WAK17 isoform 1 and the downstream hypersensitive response.
Subcellular Localization:
Membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Localizes to the cell surface of spores.
Domain:
The CFEM domain mediates interactions with host proteins.
Sequence:
MFSLTKSVLFTSIVAIAAQATTAVSSPTQTSLPGLASQVPNCVAVCLRNLHESIGCDVGDIVCLCKSKASLISKVGLCVVGSQCDFEDASSSTDIVRDMCDLVAEDPGTAVIASASKVLDAVVASATTSDIEAPTSTNAAGLVAYDVVKVVVVGAAAAIAI
The following text describes a protein:
Function:
Expression in E.coli induces sulfate uptake during early- to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQAMAYATVAGLPPAAGLWASIAPLAIYALLGSSRQLSIGPESATALMTAAVLAPMAAGDLRRYAVLAATLGLLVGLICLLAGTARLGFLASLRSRPVLVGYMAGIALVMISSQLGTITGTSVEGNEFFSEVHSFATSVTRVHWPTFVLAMSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDAKGIAIVGRIPSGLPTPGVPPVSVEDLRALIIPAAGIAIVTFTDGVLTARAFAARRGQEVNANAELRAVGACNIAAGLTHGFPVSSSSSRTALADVVGGRTQLYSLIALGLVVIVMVFASGLLAMFPIAALGALVVYAALRLIDLSEFRRLARFRRSELMLALATTAAVLGLGVFYGVLAAVALSILELLRRVAHPHDSVLGFVPGIAGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRRRALTVVDQDPGQVEWFVLNAESNVEVDLTALDALDQLRTELLRRGIVFAMARVKQDLRESLRAASLLDKIGEDHIFMTLPTAVQAFRRR
The following text describes a protein:
Function:
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MADDSAPLEPKGKQIASEDTLGDTTSIQAQVESENEEDNDETTTGATDTPATGKKKKSKRKKIKAALGVGASSTGSSGDTTRDDLSKAVAGLSKSQIGELLALNPALAQQIGAVDGDLSGKQAAEAVRKLSLEDIMTGLASSGKNVKEMGAYKFWQTQPVPKFGESSEVIEEGPFKIVDPEQVPKEPGPLISGFNWVTMDMTSDEALQEVFDLLYGHYVEDDEAMFRFNYSKSFLRWALMSPGWSKEWHVGVRATASGKLVAFISAIPVALRVRNKTLKASEVNFLCIHKKLRSKRLAPVLIKEITRRCYLQGTWQAIYTAGVVLPKPVSTCRYYHRSLDWKKLHEVKFSPLPPGSTPERQVRKFALPSNTSTRGLRPMESKDIDAVLDLLKKYLAKFDMAPVFTREEVEHWLFNRIENPAEQVIWCYVVEDPTTKKLTDFFSFYCLESSVIGHPKHTNVRAAYLFYYASTIALDPASSRTDLGKRLNELTHDALIIAKKFKFDVFNALTLMDNTLFLEEQKFGAGDGQLHYYLYNYKANNIAGGVDKMNRIHSAGSGVGVVML
The following text describes a protein:
Function:
Essential cofactor of the RNA polymerase L that plays a central role in the transcription and replication by forming the polymerase complex with RNA polymerase L and recruiting L to the genomic N-RNA template for RNA synthesis. Also plays a central role in the encapsidation of nascent RNA chains by forming the encapsidation complex with the nucleocapsid protein N (N-P complex). Acts as a chaperone for newly synthesized free N protein, so-called N0, allowing encapsidation of nascent RNA chains during replication (By similarity). The nucleoprotein protein N prevents excessive phosphorylation of P, which leads to down-regulation of viral transcription/ replication. Participates, together with N, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place (By similarity). Recruits host PI4KB and remodel the host endoplasmic reticulum membrane to form viral replication factories (By similarity).
Miscellaneous:
MISCELLANEOUS: The P/V/C gene has two overlapping open reading frames. One encodes the P/V/W proteins and the other the C/Y proteins.
Subcellular Localization:
Host cytoplasm.
Domain:
The N-terminus consists of a long intrinsically disordered tail (By similarity). The central part contains the coiled-coil multimerization domain (PMD). Forms a four-stranded coiled coil structure. The C-terminus constitutes the alpha-helical domain that binds to the nucleocapsid (N-RNA complex) (By similarity).
Sequence:
MDQDAFILKEDSEVEREAPGGRESLSDVIGFLDAVLSSEPTDIGGDRSWLHNTINTPQGPGSAHRAKSEGEGEVSTPSTQDNRSGEESRVSGRTSKPEAEAHAGNLDKQNIHRAFGGRTGTNSVSQDLGDGGDSGILENPPNERGYPRSGIEDENREMAAHPDKRGEDQAEGLPEEVRGGTSLPDEGEGGASNNGRSMEPGSSHSARVTGVLVIPSPELEEAVLRRNKRRPTNSGSKPLTPATVPGTRSPPLNRYNSTGSPPGKPPSTQDEHINSGDTPAVRVKDRKPPIGTRSVSDCPANGRPIHPGLETDSTKKGIGENTSSMKEMATLLTSLGVIQSAQEFESSRDASYVFARRALKSANYAEMTFNVCGLILSAEKSSARKVDENKQLLKQIQESVESFRDIYKRFSEYQKEQNSLLMSNLSTLHIITDRGGKTDNTDSLTRSPSVFAKSKENKTKATRFDPSMETLEDMKYKPDLIREDEFRDEIRNPLYQERDTEPRASNASRLLPSKEKPTMHSLRLVIESSPLSRAEKAAYVKSLSKCKTDQEVKAVMELVEEDIESLTN
The following text describes a protein:
Function:
Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of three 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. Thus generates the genus-specific LPS epitope of Chlamydia, composed of the trisaccharide alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Sequence:
MIRRWLTSRLYDAFLVCAFFVSAPRIFYKVFFHGKYIDSWKIRFGVQKPFVKGEGPLVWFHGASVGEVSLLAPLLNRWREEFPEWRFVVTTCSEAGVHTARRLYESLGATVFVLPLDLSCIIKSVVRKLAPDIVIFSEGDCWLHFLTESKRLGAKAFLINGKLSEHSCKRFSFLKRLGRNYFAPLDLLILQDELYKQRFMQIGISSDKIHVTGNMKTFIESSLATNRRDFWRAKLQISSQDRLIVLGSMHPKDVEVWAEVVSHFHNSSTKILWVPRHLEKLKEHAKLLEKAGILFGLWSQGASFRQYNSLIMDAMGVLKDIYSAADIAFVGGTFDPSVGGHNLLEPLQKEVPLMFGPYIYSQSVLAEKLREKEAGLSVNKETLLDVVTDLLQNEKNRQAYIEKGKSFLKQEENSFQQTWEILKSQITCMKI
The following text describes a protein:
Function:
Mediates export of peptides generated upon proteolysis of mitochondrial inner membrane proteins.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MDPIRFGLSRVPFAHCYNKRVIFRANYLVPLTWLKNNVAYKSTNTLLLPTPNAEYYSTSKLSSQVNVSLNSLSQKASSGSKIYPFKNSFPLPFSRSILPIRSLAFLKLCVRHNSTVPSKDEQAQDISKINTNGTLQTPNKKVNVFRLFTLARGQGWNFFIAGSLLLVSSGVTMSIPYIVGKILDAGSSGDSSVTHIMGIPSGTFYIGLLGLFFLGSACNFGRIITLRLLSERIVSRLRARLFAKCMSLDGAFFDFHKHGDLISRLTTDSSIVGKSLSMYLSDGLRSSVSAIAGIGMMLYVSMRLTGYMSLIVPPIALGAFFYGEYVRKLSRTTQDALGDLTRVSEEKLANVRTTQAFLGERQEVNRYNDYIRNLFVLAKREAFASGIFFGSTGFLGNATVIAILALGGRMVAAGDITVGQLSSFLLYTVYAGGSIVGLSGCFTDIMKGLGAASRLFELLDAKPKIAPTVGIPVPVTVGKAILSFRNVGFAYPTRPSASIFDNLSFDIHPGTNVAIVAPSGGGKSTISQLLLRFYAPSSGKILADGVDISTYNVHQWRSHFGLVGQEPVLFSGTIGENIAYGKSNASQEEIEDAAKRANCSFVLSFPEKWSTQVGTRGLQLSGGQKQRIAIARALLRNPAFLILDEATSALDGEAEVMVDKTIQSLMHNRSMTTITIAHKLATIRRADQIIVVGDGKVLEQGSFERLSRPGTNFYKLMRWQLGKVEP
The following text describes a protein:
Function:
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
Subcellular Localization:
Nucleus.
Sequence:
MDKTENLEQILKKASLENMSSNPILPLVATSSLVNKESDDSDSSNSLFKTQLSDSSSELEPFNLKVVFENWKKKKIQKKKRKYKPSGRPKGRPKGSTKTTQSLAIMPKKDLFKDKGLQFPLVESENGRKPLLWKKILGFEQAVARGFFNYVKEQKYESHLREALKHLGAGEDLVKEDFGVRRYKYLEDDDESISPIEEPNAENNQLDDQYDCDVKLVDNSCFIISTKFPKKTKSKMKKRRLDITLKITTREMKQICLGKRKIPLAKGREMEFALRKLMIYENFLDIKFLISYSEAYLLV
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSRTKKNKPGAAERAAKAAATAIESAATPVADAAPAAATAAKPATTASEAQATTSSKRGKLIRPRGKRGGIKNRKGGASAKSAQVQQSAVKDARKAKGNAAADSKDFTDSNAAPVPPAEHAEKIAKFHTLLKQLEQAKTAADKDEIQAGLDSLGGLAQYQAWSLTGSAKAGQTPTSKWCMEALATVYKHDRDLPKFRVLDVGAITGTAYEKYRWVDATYIDLHPQGDNVQKYSFFEFPVPTDTKQRFNMVALSLVINFVGDVRKRGEMLRHVHKYLPDNQDTPGFCFLVLPLSCLTNSRYMNQSHLRAILSSLGFNVVKQSDSNKLSRWLLQRKPLKERQEAAANNGNAAAASDEWDGTVFKKRDINPGKDRNNFAIVVDPKPEQ
The following text describes a protein:
Function:
Aminoacyl carrier protein. Can be charged with L-glycine via the formation of a thioester bond between the amino acid and the 4'-phosphopantetheinyl prosthetic group, catalyzed by the bll6282 ligase.
Sequence:
MHNTAINVQNRVLSVVRSVLQQNAISADVHPESRLVDIGLSSMGMVELMLKVEAEFDLILPQFEITPENFRSVKAMERMILNQLGSGSG
The following text describes a protein:
Function:
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues (By similarity).
Sequence:
METTEEVVAPATTQQPATEVGSAKPTTSTYSKKQKKPKATTTTTTTDGTTPTHNEHASAKDPRKAQDDQVMGTNNSSIVSKRSVEKLYYPNEPHFFRFFVKKFQRRAPLINRGYHFRLHVIDVLVRNFLQEQRTGDAKGKRKVVVNLGCGSDVLPWQCLARYPDACRSGEKDGAKFVDVDFPDLIERKKRTVLETPELLGPLTNVVVPEFAPVPSTPAATTTAAATTTTTTELKTTAATASSTSTEAPQKPKKSPKPKDKSKAARAPAPTTAPTGIVFTSDQYVQIGCDLRDLATLQDSLTRAVGGDLSSCTFLFVAEVSITYMETPGADAVIQWASSLGDSEFVLLEQLLPSGPTHPFASTMLSHFHKLNTPIKSVDVYPTVASQVERFRSRGWGSGDVRVWTLWEAWADAEDTFVNAAERRRLDEVEPFDEWEEFALFASHYCVVRARTVARDGQNKKKERGIPNGRELGLPVEKVKVRWDDVPGQRGQRRFAAGAVLTSSSPSSEKKEEVKLLNVMGLGTKSRLQNCDVYGRKKVGDADEADGTDEEKTAVPFTFREGGPSTRMCHSLTDFGTAQLLVGGRASPSTPLKDCWLLEKTNGSESEWAWKRTNDLPIPLYRHSVTRLGKTDMALLAGGRGVADIFPDWLLYEPKLGWIRCEIAGDVKPTSVYGATLACLRQESDSFSGVFTGGLSDDGLIADQLLAWNLDVSNSSRPVVTFVPLQVKSGDDGREEALSRLLLTRFGASCLPQSRTDFLVFGGVIKDHLLDMEDEILLCSLKGDGELTITRRLVPEAANAKSPSHPGPLLLVGTSPVVTPDDGSLMIVGGGATCFSMGTFWNKGISTLELALPAAVENEASPIPAYGWVHEKTVDIIPGEPRSLPLRNQAPNGAEGNANGSVSVRIQPIPRVRLENAEDFARIVREGRPVVLEGLNLGDCVSQWGNGDYVAKKVGTDRKVVIHESTTPAMDFTTKNFRYVTTEFGDFMRRVEKGDRLYLRALSTDKPTEKPAVLSDDFPSLATDFVLPPELALVGDRLFSSVLRVSGPVNMWLHYDVMANVYCQIGGSKRMILFPPSDVEHLGFAPGASSSSIDVFSTLFGESSDSRYLAQVTHPHEAVMTPGDVLFLPPLWLHTATPTSDSSIAVNVFFRDLEGGCYAAGKDVYGNRDLAAYEKGRTDLTRIANSFQKLPAEAREFYLLRLADELRRKAKGAQ
The following text describes a protein:
Function:
Is involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
VHPRGPQQQERPAPRQEPHPQEGSRSPPWRPRRLRIARHRRVHRRGVQRPAPPASRPLPPRHGSLLGSLHRPQGNIFFTRPSWLALWLEGEEQKGFLKETKENLALLEAQLGGKRFFAGDSIGYLDIAAGGLAHWVGVLEEVTGVSLVAGDDGDDEYPALRRWTNEYTANDAVKLCLPNRERIAAFFTPKDKYKIMARAMLRQQ
The following text describes a protein:
Function:
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity).
Sequence:
MQTSHSLPSAQLPLFQEAFWASNGAPLLDDVIDSPSSASIEEPAAFSELSLSGLPGHCLTLLAPILRELSEEQDARWLTLIAPPASLTHEWLRRAGLNRERILLLQAKDNAAALALSCEALRLGRSHTVVSWLEPLSRAARKQLSRAAQLGQAQSLNIRLG
The following text describes a protein:
Function:
DNA helicase that loads on single-stranded (ss)DNA and translocates in a 3'-5' direction, probably involved in DNA repair. Archaeal orthologs have double-stranded (ds)DNA and/or RNA:DNA helicase activity.
Domain:
Composed of 2 helicase domains, a winged-helix (WH) domain, and Lhr-specific domain 4.
Sequence:
MGRVEYLKKEYSDEEIYEILEKPVKEWFKRKYKTFTPPQRYAIKEIHEGKNVLICSPTGSGKTLSAFLAGINELIKLSMENKLEDRIYILYVSPLRALNNDIERNLKEPLKEIYDVAKEIGIELDEIRVAVRTSDTTSSQKQRMLKKPPHILITTPESLAIALNSPKFSQLLSGIKYVIVDEIHALTNKRGVHLSLSLERLNRIANFIRIGLSATIHPLTEVAKFLVGNGRDCYIVDVSYKKEIEIKVISPVDDFIYTPSEEISKRLYNLLKKLIEEHKTTLIFTNTRSATERVAFYLKQLGVEKVETHHSSLSREHRLEVEEKLKKGEIRVCISSTSLELGVDIGSIDLVILLGSPKSVSRALQRIGRSGHRLHEKSKGIIIPFDRDDLVENVVLAYDAKIGKIDRIHIPKNCLDVLAQHLVGMALEKVWDVDEAYNLIKKAYPYKDLSKKDFLDVLNYLAGGIEEKNVYAKIWLKDNKFGKRGKSVRAIYYMNVGTIPDETAVDVIADGKYVGEVEEEFAEKLMKGDIFVLGGKTYKYLGGRGNKIRVKEVFDEKPTIPAWFSEQLPLAYDLALDIEKFRKEVLSSDIEEIREKYDIDEKTAKAIKNYMDEQNKFAIVPDDEKVLIENFDEEKRRYYIFHFVAGRRANEALARAFANYISKIKKCNVRISVNDYGFALILPKNRKIKRADITELFNLDVVKNVKESIERSEILKRRFRHVATRGFMILRRYMNRKISVDRQQFNAEMLLKYCKEVNHPLYRETLREILEDSLDIDNALDYFEKIKRRKIYYLELPSPSPFAFNLVVSASSDVIFMEDKKKMIAELHKKVMEFISMKGKK
The following text describes a protein:
Function:
Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSEVPHKKKVRSKKSRNAPQELSTSKPCGRKLLDSEESHKITDPRFREECGEIDKVGFVKNYAFLQKNREQEISQMQKELEDDPTLADDPEFKKRLQSLKDQHKTMASKIDDVNASIQWHREERQRIAEGKRPFWMGKQDMKLMQQKKKFDELQSTGRLNAYLKKRNKKLLAKDKKSGII
The following text describes a protein:
Function:
RNA-binding protein that regulates alternative splicing events by binding to 5'-GCAUG-3' elements. Regulates alternative splicing of tissue-specific exons.
Subcellular Localization:
Nucleus.
Sequence:
MLSSPTVILQPYGLPVYPQTASCYPGIVQGAAAQEAGPGNGDPSLPQVYAPPPSYPPPGQAPPTPAARLPPLDFSAAHPNSEYADHHQLRVYQGPQHDGTESITASNTDDSLAPVTSDPQSLSVSVASGSGAAGGSDEEGGGKAQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFESAVEADRAREKLNGTIVEGRKIEVNNATARVVTKKPQTPLVNAAGWKINPVMGAMYAPELYTVASFPYPVPTPTLAYRGSGLRGRGRAVYNTIRSAAAAATPAAVPAYPGVVYQEGLYGAEVYGGYPATYRVAQSASAAATATYSDGYGRVYATATDPYHHSVGPTTTYGVGTMASLYRGGYNRFTPY
The following text describes a protein:
Function:
Serine/threonine protein kinase acting as a regulatory component of the plastid protein import machinery by phosphorylating import receptors (e.g. the A-domain of TOC159, TOC120 and TOC132). Supports preprotein import and contributes to efficient chloroplast biogenesis, thus being required for survival during de-etiolation.
Subcellular Localization:
Plastid, chloroplast outer membrane; Single-pass membrane protein; Cytoplasmic side.
Sequence:
MASKIIAGKPDDTEYEIIEGESESALAAGTSPWMNSSTLKLRHRIGRGPFGDVWLATHHQSTEDYDEHHEVAIKMLYPIKEDQRRVVVDKFEDLFSKCQGLENVCLLRGVSSINGKICVVMKFYEGSLGDKMARLKGGKLSLPDVLRYGVDLATGILELHSKGFLILNLKPSNFLLSDNDKAILGDVGIPYLLLSIPLPSSDMTERLGTPNYMAPEQWQPDVRGPMSFETDSWGFGCSIVEMLTGVQPWSGRSADEIYDLVVRKQEKLSIPSSIPPPLENLLRGCFMYDLRSRPSMTDILLVLKSLQNSEEEQVRRGIDSREIRKSSATLGYTEWFLSKDHLQVRDTVRSRKPANSCKHENMDVPEGMVVGLERDSTDPDGFVLVKVHGVHDPLRVHVSVLERVTNGLASGDWVRLKVRKDKRHSPVGVLHSIDREGNVAVGFIGLPTLWKGTSSQLQMAKVYSVGQFVKLKANVVIPRFKWMRKGRGIWATGRISQVLPNGCLEVDFPGMLPFGEEHGSYLADPAEVEIVNFNTCQGAVEKYQHLEDFHWAVRPLLIAMGLLTAMKLGICVRKKIGRSKDGKQRDGSTGQGDCKIPDGKGSDKSKWLVFF
The following text describes a protein:
Function:
Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
Subcellular Localization:
Cell inner membrane; Single-pass type III membrane protein.
Domain:
The transmembrane domain is a dimerization domain.
Sequence:
MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQTGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
The following text describes a protein:
Function:
Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAKGSHNSSVARPKPKAATVFEQDSDGSDTRSLQLDSGSELGSDMGESADEEEEEEEEEEEEEEEEQPKYAQFMDDSDLEDATDDESEDENEDDVEHGAYSIEEADSDDEQDDLRQQMNKLPFSALMKAKQQMNGFSSDDDQDVFSEPDISDLEEDEFAQDRQRLAAAKAGKRPDCKSNGSSNSSRSEEALEQKRLEVRERLRQLKGGSTSTVGSSSKGAADEAWAEARKQREQRRKDANQRKELAKRSNKNAPTEISSKRPVSRRRNVIETASSQVRDPRFESLSGSVNKDLFAKSYSFLPEMFKDELGTLKKTLTKLKKLEAAQAGPKAKSEQALAIREERAKVEAALRRAEGLAGERERRARESAVKGKIKSQNKERVEKGLLPFYPKKSEIKQMLLKDKYDRLSGGGNQEGKRASGQEKKQLKKALERRRKKNAQKEKRDMPAGIGFAREGNGALPKRKRNTAGGDSNKRARF
The following text describes a protein:
Function:
N(6)-adenine-specific methyltransferase that can methylate both RNAs and DNA. Acts as a N(6)-adenine-specific RNA methyltransferase by catalyzing formation of N6,2'-O-dimethyladenosine (m6A(m)) on internal positions of U2 small nuclear RNA (snRNA): methylates the 6th position of adenine residues with a pre-deposited 2'-O-methylation (By similarity). Internal m6A(m) methylation of snRNAs regulates RNA splicing (By similarity). Also able to act as a N(6)-adenine-specific DNA methyltransferase by mediating methylation of DNA on the 6th position of adenine (N(6)-methyladenosine). The existence of N(6)-methyladenosine (m6A) on DNA is however unclear in mammals, and additional evidences are required to confirm the role of the N(6)-adenine-specific DNA methyltransferase activity of METTL4 in vivo (By similarity). Acts as a regulator of mitochondrial transcript levels and mitochondrial DNA (mtDNA) copy number by mediating mtDNA N(6)-methylation: m6A on mtDNA reduces transcription by repressing TFAM DNA-binding and bending (By similarity). N(6)-methyladenosine deposition by METTL4 regulates Polycomb silencing by triggering ubiquitination and degradation of sensor proteins ASXL1 and MPND, leading to inactivation of the PR-DUB complex and subsequent preservation of Polycomb silencing.
Subcellular Localization:
Nucleus.
Sequence:
MSVVHHLPPGWLLDHLSFINKVNYQLCQHQESFCSKNNPTSSVYMDSLQLDPGSPFGAPAMCFAPDFTTVSGNDDEGSCEVITEKYVFRSELFNVTKPYIVPAVHKERQQSNKNENLVTDYKQEVSVSVGKKRKRCIAFNQGELDAMEYHTKIRELILDGSSKLIQEGLRSGFLYPLVEKQDGSSGCITLPLDACNLSELCEMAKHLPSLNEMELQTLQLMGDDVSVIELDLSSQIIENNSSFSKMITLMGQKYLLPPQSSFLLSDISCMQPLLNCGKTFDAIVIDPPWENKSVKRSNRYSSLSPQQIKRMPIPKLAAADCLIVTWVTNRQKHLCFVKEELYPSWSVEVVAEWYWVKITNSGEFVFPLDSPHKKPYECLVLGRVKEKTPLALRNPDVRIPPVPDQKLIVSVPCVLHSHKPPLTEVLRDYIKPGGQCLELFARNLQPGWMSWGNEVLKFQHMDYFIALESGC
The following text describes a protein:
Function:
Plays a role in biomineralization; might regulate pH in the magnetosome.
Miscellaneous:
MISCELLANEOUS: This bacteria makes up to 20 cubo-octahedral magnetosomes of about 45 nm in diameter which contain membrane-bound crystals of magnetite (Fe(3)O(4)); MISCELLANEOUS: Expression of just the minimal mamAB gene cluster (amb0961 to amb0978), including this gene, is sufficient to form a minimal magnetosome chain with small magnetite particles.
Subcellular Localization:
Magnetosome membrane; Multi-pass membrane protein.
Sequence:
MIGLLTLAVFVATFAVIYRWAEGSHLAVLAGAAALVVIGTISGSYTPVMALRSVYFETLALIFGMAAISALLARSGVYAYLAAGTAELSQGQGRWILVMMALVTYGISLASNSLVTVAVVVPVTLTVCFRTGIDPVPVIIAEIIAANLGGASTMIGDFPNMILASAGKLHFNDFIAGMMPVCLILLAVMLVFFERRLGDWKGSEIPVDPVWARGEALRHSAIDRRLLSYGLIIFGVTVAGLILAGPLKVRPGWIAFVAGVTALGLGRFKDDEFFSACGGTDILFYGGLFVMVGALTSVGILDWAVNWLEGITAAHDRVRAILLMWMAAAVTIFVGGGTSAAVFAPVAATLRLDGDGQAAWWALALGIMAGSVAALPGATAGSLAMTQYSGFVKRHPELASAAAAGLQFTHREYVRWGMPLMGIFLVLGTVYIAVLVG
The following text describes a protein:
Function:
Bifunctional nuclease with both RNase and DNase activities. Involved in basal defense response. Participates in abscisic acid-derived callose deposition following infection by a necrotrophic pathogen.
Sequence:
MIKMRDGRHLKCVHNNPQGGHLPDYAPHPATVLRMEDGTGLLLPIIVLEMPSALLMAAVRNVPNCKFSDLGGGKAILPNFLQRLFILLLKKTNVGARPTMYQVVNDMVEKMGYTVKLVRVTKRVHEAYYAQLYLTKSDNDAECISFDLPPDDAINIAVRSKEITCLKHLFYTRLTDTSLFWS
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MSSKAPSSNSVAHARRIVQQLKVEAGFERIKVSKASADLMTYCTENARNDPLLMGIQASENPFKDKKPCTIL
The following text describes a protein:
Function:
Sequentially removes dipeptide units (NH3-P2-P1-) from the amino termini of peptides and proteins. Is able to catalyze the removal of Asp-Arg from the amino termini of angiotensins I and II. Has slight endopeptidase activity on N-terminally blocked peptide derivatives which contain arginine residues at the P1 position. Does not hydrolyze Ala-Ala-Ala and Ala-Ala-Ala-Ala substrates or insulin beta chain.
Sequence:
MKPTSLLLAATVLMSTPITSALAASATPPDVAKKPHVVKAPHGAERNDEYYWLRDDKRENKEMLAYLNAENAYTDAVMAPLKPLEDKLYDEVVARIKQDDASVPYRERGWWYYARFVTGKDYPVHARRKDGPGVDAVSIQAANAAGDFAGEQVLLDVNALGAGKDYYNVGDYEVSQDNRLLAYADDTNGRRQYTIRFKNLDTGELLPDTVTNAEPNLVWSDDGRTLFYVDKDPETLLSKRVKAHVLGTPASQDALVYEEEDDSFYMGIGRSRDDKFICISVESTVSSEMRCTPAASPGVFTVLAPRERDVEYQADHLGDRWVIRTNADGATNFKIVTAPTDSTSRKDWKDWVAHRDDVFVEGFELFDGFSVVAERANALESLRVIKADGSSDYVKADESAYSMGLSANPETGTDWLRYSYTSMTTPATTYEINTKTGERRQLKQQPVPGYDASKYVTERVWAPARDGKTKIPVTLVYRKDVARDGKAPMLQYAYGSYGASMDPNFSITNVSLLDRGVVYALAHIRGGQEMGRAWYDDGKLYNKINTFTDFIDVTDYLVKEGYAAKDRVAAMGGSAGGLLMGAVSNMAPEKYKVILTLVPFVDVVTTMLDPTIPLTTNEYDEWGNPEEKGYYDYILTYSPYDNLQAKAYPAMFVGTGLWDSQVQYWEPAKYVARLRDLNTGKGPVVFRTNMEAGHGGKSGRFRQYRERAEMFAFMLDQLGVASK
The following text describes a protein:
Function:
NAD-dependent dehydrogenase that has high activity with L-rhamnose and L-lyxose, and shows only low activity with L-mannose. Has no activity with NADP. Catalyzes the first step in an alternative pathway for rhamnose utilization that does not involve phosphorylated intermediates.
Miscellaneous:
MISCELLANEOUS: Part of gene cluster that contains the genes for this rhamnose catabolic pathway.
Sequence:
MTGLLNGKVVAITGGVTGIGRAIAIEMARNGAKVVVNHLPSEEQAQLAKELKEEISDGENNVLTIPGDISLPETGRRIVELAVEKFGEINVFVSNAGVCGFREFLEITPETLFQTVNINLNGAFFAIQAAAQQMVKQGKGGSIIGISSISALVGGAHQTHYTPTKAGILSLMQSTACALGKYGIRCNAILPGTISTALNEEDLKDPEKRKYMEGRIPLGRVGDPKDIAGPAIFLASDMSNYVNGAQLLVDGGLFVNLQ
The following text describes a protein:
Function:
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
Sequence:
MSNNQVPNPRPEIVGPQEVQPPYPIFFQGEVVHGFGRGSREMGIPTANILESAVQELLKERESGVYYGFAQVADGEVYPMVMSVGWNPYYNNEKRTAEIHIMHSFPQDFYGQQVRAAVMGYIRPELDYEGIDKLIADIHFDIKVAHNSLSRPDYERYKHSSFFQSPSKSPARAEEQK