lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation (By similarity).
Subcellular Localization:
Postsynaptic cell membrane; Single-pass type I membrane protein. Note=Localizes to the postsynaptic cell membrane of the neuromuscular junction.
Sequence:
MRDLLVVPLGHVLTLAALSLAETLQKAPFISTPLETVDALVEDVPKFVCVVESYPEPEITWTRNSIPIRLFDTRYSIQRNGQLLTILSVEDSDDGVYCCTADNGVGAAAQSCGALQVKMRPKITRPPVNVEIIEGLKAVLPCTTMGNPKPSVSWIKGETVVKENARIAVLDSGNLRIHNVQREDAGQYRCVAKNSLGSAYSKPATVVVEVFARILKAPESQNITFGSMVTLRCTAAGAPVPTVTWLENGKAVSAGSIAESVKDRVVDSRLQVYVTRPGLFTCLATNKHSKTFGAAKAAATISVSEWSKLYKGDAGYCSTYRGEVCSAILSRNALVFFNSSYADPEETQELLVHTAWTELKTVSSFCQPAAESLLCNYIFQECKPSGVGPAPKPICRENCLAVKDLYCFKEWLSMEENSQRGIYKPGLMLLALPECNRLPSLHQDPSACTHIPFFDFKKENITRTCYSGNGQFYQGWANVTASGIPCQKWSDQAPHLHRRTPQVFPELSDAENYCRNPGGENERPWCYTKDPSVTWEYCSVSPCGDASLSLGTRKPNGETQNLPPPPSYSPTYSMNVIILIISSFALIVILGIITLVCCRRRKQWKNKKRESETPTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEYLRDRSPRNLCSLVQGGLEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNMYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGMQPYYGMAHEEVIYYVRDGNILSCPDNCPLELYNLMRLCWSKLPADRPSFASIHRILERMYERAVASPQV
The following text describes a protein:
Function:
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
Sequence:
MRLFIGIEVPQSPKLLEIFEIVKNAGADIKLVEPYNIHITLLFLGEVREDRVEEVKDSMSGLKFNKFKVTLKGLGAFPNLTRPRVVWVGIVEGQQQLRQIRSYILNELLKRKIRPEDDKDFSPHLTIGRVKSYNSISNLINTINENMNVDIGTFEVNNVVLFKSTLTPKGPIYDKLFEVSSIDRGGSTEDNKTH
The following text describes a protein:
Function:
Mediates magnesium influx to the cytosol.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTKPPNNQASQFWRLPTDALCTRLGCSLQGLTATEAAERLGRFGPNSDAPPRIEGAARAVLRRLLEPLSLILLVAGIVSMLTGDDVGGLIIVLILAGSIGLDTIQEGHAVRAAEILRRSVALKAEVRRDGAFCEIDVDHVVPGDLLRVRAGDIIPADGLILESTAFTAGEAALTGEPYPVQKRAGAATDPDDTSNALFRGAVAQTGEAIALVVRTGRDTVFGAAASALAETQAPSPFERDLREFGLVIARATLALVLVVLTVRVVFGRPVLDSLLFAVALAVGLTPELLPMITTVTLSRGALRMAGRKVIVKRLAAIHDLGAMTVLCTDKTGTLTSAEITLARSLDAEGKDNARAAQLGAIAASLGGDRGSLDAALVAGRPDAAQGWTLAGRQAFDFSRRLGSVLATGPEGTLLIVKGAPEAVLALCTMDERARTAALARVRELASEGLRTVAIASRAWSGVLREVETEDETDLAFEGFCAFADPPKPTAAAAIAQLAARGVGLKILSGDDPVVVKRLASLVGLNPERVLSGTDVAALSDAALAVQVRSTDAFGRLAPDQKSRIVRALQAGGEVVGFLGDGINDAPALKVADVGLSVDGATGVAQAAADMILLASDLEVVADGVAEGRRTFANILKYVRMGASSNFGNMLSMAIASMVLPFLPMLPTQILLNNLLYDLSELGIPFDRVSAQATAQPQVWSMSNLARFAAIMGPLSSVFDFLTFGALIMLFHASPGEFRTAWFIESMATQILVIFVIRTNGRPWRNWPDPVLSASSLIALLVAMVVPFTPVGTWFGFVAPPPLMMAGIALLVVVYLACAELLKPFAIRSKRKR
The following text describes a protein:
Function:
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MESENKNNNKKVKEESKVKVKFITNDANIRVTDTPIAVPVRLGRLGLSEVIHHLREEENETSKPFDFLINGKFIRTTLDKHIKNANLSEEQIITIEYLEAITEPKREKECQHDDWVSCVDGSNFGLVVSGSYDLGVRVWGYDGELISTGTGHLAGVKSVCWISDKNADNLSFVSASMDKTLRVWNFNKSQSEIKALACLKEHTGTIESVYVSPDSSRIVSASMDSTIKLWSIKDIPNQHATTSSSIEKSNSKKRRLANNTNNETAAVDQQSEIIHNITESLASVTVPNSQGVTVVNWTTQFQMLSGSMDSKIRLWDVSTLVANDTIPTPAPLTDLDYSMESGLIVTAHKDRIVRIWDPRSSDETKSQTQSLISHKTWVTSVNWNPSSKYHCCSTSHDGTVKYWDIRTKIPLYTIDTLEKSKDKVLSSSFISNKNKNINDYSIVSGGTDSKLRIHYNDKQEQQQ
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MNRIKLNSLQQKVHEAIIMQVIPVIRDGLNTIISTPSGTGKTLCYSIPIIEQKRSIVLTPTKELSIQTYKTIRELDPNIRVSRIGSIGLIAPIVEMISDLEAKKLQNYAKERLQRMNDSLRGQLNWDLVDICISTPGQLAQLVKLGCRIQEVNCLVIDEADLTWGDVSFRESIYTIQRYLNINQFVLCNSVNTIKDEKEMKTVDGSKFTSYISKDYMQIPKRKIEFMDKPLQEYLDNQKTIIFVDGEKECQEVQKIVGPSKCFNSGQSVEERIRNVEEFRKNEWKTLICTGLGSRGLDFPDVTQIIMYDLPRNFEAFLLQCGRLRQENGRIIVRLKDSFESAIYSEYERYKYVFPNSCVKL
The following text describes a protein:
Function:
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MSFYTVVATFLSVVLASAVFWVLAPKENQTVWRSTIILSMSMMFLMWAVTYLSQLHPLVVPRRSDLRPEFAE
The following text describes a protein:
Function:
May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney. Plays a role in the regulation of lipid metabolism.
Subcellular Localization:
Apical cell membrane; Multi-pass membrane protein.
Sequence:
MVNFDKNRIILLSHLNVTLYALCFWIQIGTLPYLTQKFDVDPITFGNLQTTFAVVQLMGGPLFGRFGDLFGCKYALALAFISAFLSYFLLGVANTVFIIFLSRLPSVFMHAMQGAQMVITDLTEPSERPDKLGKLGLSYAVGMVLGPVIGGWCTTYANEQVAAFVAACGSLLSIVLVVLFIPSNTKGFILKENTEKTLKKSKKLLDFDVFTSLIWKNPSARKLLFVKMLSGLPVGILHGMFSMIALNHFHLSAEANGYVLSYAGFLSIISQGLVIGRLTKRGFNEWSLINGCVAVLCVSNALMSILVNGVIGFCISLIPMVVAGAVFSTVIQAMLTKTVQSEDTGSMLGVSMAVHSLIRSVSPTIGGFLFQYYGFWSFGAIGFLCNGLLLVYLLISNPR
The following text describes a protein:
Function:
Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation.
Subcellular Localization:
Nucleus.
Domain:
The QLQ domain and WRC domain may be involved in protein-protein interaction and DNA-binding, respectively.
Sequence:
MRMLLGIPYVDKSVLSNSVLERGKQDKSKLLLVDKCHYELDVEERKEDFVGGFGFGVVENSHKDVMVLPHHHYYPSYSSPSSSSLCYCSAGVSDPMFSVSSNQAYTSSHSGMFTPAGSGSAAVTVADPFFSLSSSGEMRRSMNEDAGAAFSEAQWHELERQRNIYKYMMASVPVPPELLTPFPKNHQSNTNPDVDTYRSGMFSIYADYKNLPLSMWMTVTVAVATGGSLQLGIASSASNNTADLEPWRCKRTDGKKWRCSRNVIPDQKYCERHTHKSRPRSRKHVESSHQSSHHNDIRTAKNDTSQLVRTYPQFYGQPISQIPVLSTLPSASSPYDHHRGLRWFTKEDDAIGTLNPETQEAVQLKVGSSRELKRGFDYDLNFRQKEPIVDQSFGALQGLLSLNQTPQHNQETRQFVVEGKQDEAMGSSLTLSMAGGGMEETEGTNQHQWVSHEGPSWLYSTTPGGPLAEALCLGVSNNPSSSTTTSSCSRSSS
The following text describes a protein:
Function:
May function as a transcriptional cofactor with a repressor activity.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MEITTKSSTTTDDLNNNNNKTVTPIKSENSATGHTSPPNNSTTTTTSSTSAQPITVLPTEIIKTFEHLLRKSQRLFIGLRDLPQFGRQWQPFFQKTFELYTKLWKFQQQYRSILEDKSKYGLKRCEIGEIASKIGQLYYHYYLRTSDTNYLNESYIFYEAIRLRSYFKDVSLDKTPDMMVKQLRYYARFIVVCLLLNKKKVVFDLIEELLKHVNDYTKIYKPSDAQEWSLVLQEIFSFLQADQCATFSDTNQSPSLTNSGNIINNNSNSNNNNGEHTNNTVQSHRLNHLNCPSPPFPLESTQILQQAILVGSQQNQIKFSEITLDMFRMTQSLEYEPMSEAKENDMKLKQQLTALQQQQQQQAAEAKEKNNGTDQQNTTIPSQPLQQHLHHQQQQQQNGNGSGIKKRNPHKYLLYRPTISQILLFLSYSFKELGDNKAMLLYICADGFTNEDNHVNQHIQPPPSIQQETVPSLIDDSNTNIPITTTATATNPLYNKLFTKGLTLNMQKPSQAINSPTVNNNNNNTTTNVTVPTTTTTATNVTAQTTTTTTTTNSTSTSTTSNIPIYKYNEAPFNTKVESLYPMDLLPFCRKPFFLIVNSQSSDIFNELPTFNQPFVSLLSPQSIPKKLVSNLKCGNLFTFFLHDPISAFCDISCGNKIPSKTFNNISLLAQNSLEIISKLLFECVDLHPSFSFFLLDDFLRSFIIRFIFCHATFYLHKEFQDNIYQVKSNPPLPKSLLYNQSILKSIHQLVSELDVSDQFLGLNENRLVIHEN
The following text describes a protein:
Function:
Indispensable for the control of thyroid structure and metabolism.
Subcellular Localization:
Secreted.
Sequence:
MSPFFMMSLLFGLTFGQTASVCAPSEYTIHVEKRECAYCLAINTTICAGFCMTRDSNGKKLLLKSALSQNVCTYKEMFYQTALIPGCPHHTIPYYSYPVAISCKCGKCNTDYSDCVHEKVRTNYCTKPQKLCNM
The following text describes a protein:
Function:
Activates transcription. Positively regulates six promoters upstream of the TTHB186, TTHB147, TTHB178, TTHB159, TTHA0771 and TTHA0176 genes in a cAMP-dependent manner. Regulated genes include clustered regularly interspaced short palindromic repeat (CRISPR) associated (Cas) genes, and the genes encoding a putative transcriptional regulator, a protein containing the exonuclease III-like domain of DNA polymerase, a GCN5-related acetyltransferase homolog, and some T.thermophilus-specific proteins of unknown function. The consensus DNA-binding site of this transcriptional regulator is 5'-(CT)NNG(G/T)(G/T)C(A/C)N(A/T)NNTCACAN(G/C)(G/C)-3' in which N is G, A, T or C.
Sequence:
MKGSPLFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQERTLALLGPGELFGEMSLLDEGERSASAVAVEDTELLALFREDYLALIRRLPLVAHNLAALLARRLREADLELDLLSFEEARNRVAYALLKLLRQGLGPLFQIRHHELAALAGTSRETVSRVLHALAEEGVVRLGPGTVEVREAALLEEIAFGLA
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MWRLSRVALQSNRAALYMPYTPVATNPVVYFDITAEGDALGRVSVELFRDVVPRTSENFRSLCTGERGYGQCLLYYKGTPFHRIIPGFVMQGGDILTKDGRSNVSVFGYPFPDESFEGKAGKHLPGTVGMAHSGPNQNGSQFFFNLGRNEQLDRKFVVVGQVLGGWEIVNQVVKLCGSRCGTPVSRAWISDCGQSGGYMAEETQEALQGERAQHVIPGKEVLDLIQPRY
The following text describes a protein:
Function:
Plays a role in the physiological regulation of the intracellular CoA concentration.
Miscellaneous:
MISCELLANEOUS: Present with 6190 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MPRITQEISYNCDYGDNTFNLAIDIGGTLAKVVFSPIHSNRLMFYTIETEKIDKFMELLHSIIKEHNNGCYRMTHIIATGGGAFKFYDLLYENFPQIKGISRFEEMEGLIHGLDFFIHEIPDEVFTYNDQDGERIIPTSSGTMDSKAIYPYLLVNIGSGVSILKVTEPNNFSRVGGSSLGGGTLWGLLSLITGAQTYDQMLDWAQEGDNSSVDMLVGDIYGTDYNKIGLKSSAIASSFGKVFQNRMTSNKSLENNENKLYSSHESIEKNNGQMFKNPDICKSLLFAISNNIGQIAYLQAKINNIQNIYFGGSYTRGHLTTMNTLSYAINFWSQGSKQAFFLKHEGYLGAMGAFLSASRHSSTKKTST
The following text describes a protein:
Function:
Probable protease.
Domain:
The JAMM motif may mediate the protease activity.
Sequence:
MENGVEHGVDESGENQVLSSSDGEGDCDGDGEVEGEVLQPPPPPPLQITNDCVGEGVQAEEGERAPATTGAVDVTPDPGPPPTDGAAPVAILEDNMCDKDVDSDAGDEDNDDETKENYEGFNGTGRTVTLQTLMAANVLQPGLGLMTIEYLGQKFVGDLLADGKIKSHETETIFLTPSAWAMHCKRIINPDKKSGCGWASVKYKGKKLDAYKNTYLRKCALQKETPLDDCELDAERKTDTPEIVVKRTVFAHNTVSNRNVVHDANMLIESVPFTSVGKLQPFLITVNSSALLLADFHCHLTVREVCGYLGGTWDMNTHTLSITKTYPCRSTRFDRQRAGEVERDIQKMMIQDQLLLVGWYHSHPKFQAEPTLRDCDAQLDYQIKMRGASDLTYTPCVSLIISPYYDENPTLESVVKCIWIVPPNENRQSMEYGRPMLMQYSVLPDKEIPEEVRSEIQLCVDYYSQYRSEMVKFRNIYNNDVTYNEKLKNTLYPKFPSKQSDKALWNWICAVLDCEQEDDFIPPKTIKIIDNDDLEVKEEDKPVVLMDLSGDVKINPPKEEQFSEAMGGLEDSGRKAEEESNAQAEQKASELKVMSLQEQLCMPSGLNMNPVRMLSPLATPNPTSLPPVLPNLGAPVLPATPSQLLPPQVPAVTAPPAITPAVTTSALTSALNASPRDSPITIQSNSASPAKFEVPVRASPSPAKSDTSSHASTSRTRNSPAPSPGKFSVSDIARNSPSITPNKYEAAAAALVPPAAACLPTANDLMAASLAQLAGQLPPNFLQGDLAALFQQQRKDYGSSSLNQLAAAAAKVGGSKQSNASASSGLNDPNVAAAVAAYSNSFNMPLPTGVGIGGSGNSNAHSSSKSKSERSSKSSSSSSSSNSSSTSNSYKTKLMKELDELKNDPLKMSELIRSPEYAALLLQQAEALGATTLGTLGFGSDYSYLTGAGLGVPAANALTGGQSSNSSSSKSSKSSPAAAAAAALSADYNNLIQASKLLGYDSYMQQSKQSNDLNAFLQQQMAVAAASIPPPPQTASSGSSNSSSSKKQQQLQQQQHQQQQQQQQQQAAAQADYTALLQTYTKLFDPNNQFAAAMSSNKHMAGAHNELSALLSSGVGVGGGASGGGSKQKQKDIQSDMLNQLLQLEKQDSEIKALLYRQNKAAADLDALFATPSGAVVGAGSSANAMKSGSSAGNSGVSGMSSPSSLSNQAAYYNALAQEKMQDYAAFFQQQHGKYGIPDPLSKTTLAANNMFMTPSALFKIQQESLSAMMMKPPKSTTPSSARTRESSASPALERLTPTKSASSGGSGGGGSNSNSGGKYNFSAVDLAISSVPSNTPSPAPSDGSSGSSHRRPSPDIGRLYGELAPPGALLGSGGVPKKRMEFASVADLAAPPPAKMPKNNMGDDILNLSHD
The following text describes a protein:
Function:
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
Sequence:
MSGKTELKPGRTKSRSAIVLAGGRGRRMGMVEKALLEFEGKTILERLLENLFRVVDEVILSVRDIPQKEKLLPVLEKFPDREIRFCFDSREDAGPLEGIRAGLLESRSEYSFVCAGDMPFVNSEIVDLLFEKANGHDAALPRWEEDRMYEPLHAVYSRKMLLEIEKTFEGERNSVLTPVFAMKDVVFVEVSEIRGIDPELRTFANINTVEDIESMIGSVVGKVEL
The following text describes a protein:
Function:
Inhibits cell growth by regulating the Tor pathway upstream of the Tsc1-Tsc2 complex and downstream of Akt1. Acts as a cell death activator during head development.
Subcellular Localization:
Cytoplasm.
Sequence:
MFKQCRNKKRKHFSFKKFMMEVSSDTKETFLGSKSLFGMNDSTRASRCSLYNVIEADYLQGWDFQENSDDKSISNHINPALLDLDHNSCHSTFYDIMEEELDECSVEMLRKKLTGVLSKDFTIRDRHCRLFVPMDLIKRISADVVRMSQLEPRGVDGGRLIVKLDFDGCETDLGRVCSSNSSTSANDDVNNEILYEINLTLKEDSKNWPSFKQLAFMLPSMVCCRLNQPKQTIVYVGPGYKLEKVKLYKNVNVLNSPNLYLSNGYLNNNNRILPNRNLIYSHNNNNSRNDANDNSVNNNKYINNNNNNNDSNMNIVDINANNLSSSSISVTVDHDNVITNNDDSTKDDANSNLLHGEYSPTH
The following text describes a protein:
Function:
Extracellular metalloprotease that contributes to pathogenicity.
Subcellular Localization:
Secreted.
Sequence:
MGATTTGLILGLASLASAVTYGYNHVPVTKDSETVAGAFANVDDIQLRSPAFLTPDARLPGFTNGTQGPSSQDDLEEFLEQLVGRNDYMTYGTANFTSQEHRSFPYVHLSASHSSSVRRGNSSSKVRVWIQGAVHGNEPAGDETTQALLGKFDDDPEWAASILDKLELVILPRYNPDGVFYFQRTLATNIDPNRDHIKLASQQTRDIKQFMNTFNPHVIVDMHEYSASRPYGGGRYVHGSDGLFSAAKNLNINEEIRKLSEELFAKNIADDMKAAGLRAEPYVTGTSVSNSSIVADFAEAGTDSKIGRNAMGLTQAVVFLLETRGIGIADQEFQRRTAAGLTMLGSIVQTAADNAEEVFTTVEDGIERFIKSADDIVVTDYSEIKIRPFTMVDKENGSVVHPSVRFASTTPSFANLTRARPEAYLIPPAWAHLAERLRVAGCEVETLDKPFDGVVEALTITSAEIDSSYYEGVIRVTATTESSERELSLPEGSFRVSTRQKNAALAMVALEPENIDSYVSFNIVPVEEGDEYPVFRIMSSK
The following text describes a protein:
Function:
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
Sequence:
MCGIVGIVGQSSVNQTIYDALTVLQHRGQDAAGIVTVDRGAFRLRKANGLVKDVFEVKHMQRLQGNAGIGHVRYPTAGSSSASEAQPFYVNSPFGISLAHNGNLTNTLELAEGLIKKRRHVNTTSDSEVLLNLLADELQKTTSLDLTADEVFDTIAKVHEQARGAYAVVAMIIGQGLVAFRDPFGIRPLVLGKHETPTGTEYMVASESVALDAVGFEVMRDVAPGEAIYISLDGNLYTRQCAKEPSYSPCIFEFVYFARPDSTIDNVSVYASRVNMGAKLGEKIKKEWYDHDIDVVIPIPETSCDIALEIARCMDLPYRQGFVKNRYIGRTFIMPGQQERKKSVRRKLNAINTEFKGKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVYFASAAPEIRFPNVYGIDMPTSNELIAHGRDADEIAKLIGADGIIFQNLPDLIEAVRMENPEIKRFETSVFDGHYITNDVDQSYLDHLTQLRNDDAKADRNKDIGTNLELHNVCHP
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MAFIKEESEDVKIEETFRIKQEDLQEQTDLMVLKEETHQWNEMEEKKHQEITTDEKPTLTKKTSSRGRPRKSKSGCNFSCKRCRKSFSQRSNLDVHMRVHTGEKPYTCKQCGKSFYTIGNLTVHMRIHTGERPYACQKCGKSFYTTGNLAAHMRIHTGEEPYSCLQCGKSYKQNGNLEVHMRTHTGERSFICTQCGKGFSQKQNLTIHMRIHTGEKPYTCTECGKSFRCKNTLDHHMISHTGEKPFACAHCGKSFTTKARLMNHTNGHTGTTCDHCGKSLTCKDSIKQHMKIHSGERFRCIECGKGFKHKRSLVNHMKLHNGEKK
The following text describes a protein:
Function:
Probable serine protease inhibitor.
Domain:
The reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the carboxyl group of the serpin reactive site and the serine hydroxyl of the protease. The resulting inactive serpin-protease complex is highly stable (By similarity).
Sequence:
MDVREAMKNQTHVAMILSGHVLSSAPKDSNVIFSPASINSAITMHAAGPGGDLVSGQILSFLRSSSIDELKTVFRELASVVYADRSATGGPKITAANGLWIDKSLPTDPKFKDLFENFFKAVYVPVDFRSEAEEVRKEVNSWVEHHTNNLIKDLLPDGSVTSLTNKIYANALSFKGAWKRPFEKYYTRDNDFYLVNGTSVSVPFMSSYENQYVRAYDGFKVLRLPYQRGSDDTNRKFSMYFYLPDKKDGLDDLLEKMASTPGFLDSHIPTYRDELEKFRIPKFKIEFGFSVTSVLDRLGLRSMSMYHKACVEIDEEGAEAAAATADGDCGCSLDFVEPPKKIDFVADHPFLFLIREEKTGTVLFVGQIFDPSGPCSGSNSDSDDY
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MTSLPNPIPISLRPAPTPAKSSIPLPLLIARINAERGGFRNLSEDSLRQEIAEAELGEDDEENESSSEDGEAEEEPDRMKELLTARDEILGQLDAAMISLDFISLLLSKDAPVQASLSISPSLRELTGTGTLGADKIADSRVTEEQKKENKKIAKGWKASNLSKTVDAILASATRLEKEIDAETKYWEQVLAVSESGWAVCRLPQEKHTLGVRFGFAEASPTFRNRSLGALRRNPDGSIYLDQGITSPEPQSLRVLVETNGVTTGETILPKAVPQDAPIQDLILQARNTIFTSELWQEMIREVRTLASHGLQSDSKTNTITFPLSPTKKILIELQTLPTDPFRPVLGPRPDSYLANGIYLTLHLLLSLSHRRHHRIRTNPPPPISGQPRPNNPFPILRSLLTRFAHETVISSLHSLLTPLCTALTSACLSTPPTYIITPGTSSSFQNLSTPERILTTLTNHLEFLTTITFPFPLSSPPHSSIPSSFSHTTPLTPVPSILQIRTLTITQNYSRPVYYLRITPDTSPLLQICPPPPAVAEWDYVKDYILWAMGCWLAYIFSSPFTKEEEGWKVTTQANILRKIFSGLNDEGGVKQMSFEVSSIPILGPEVPGRVGEKGKEKIRISVRWEWTTGIDQEWKERRDLKQGEGAYDWYSGVGAIGAGELEEVVRKIGDVVEEAGRGKL
The following text describes a protein:
Function:
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Sequence:
MFTGLIEDVGTARRLERRGEAARLAVATALPLESVNLGDSVAVNGACLTVVAKGGGELTFDVSPESLERTTIGSLATGAPVNLERALRLGDRLGGHLVTGHVDLVATVEGRREVSGNILFTFRMASGFSRYLVAKGSVAVDGISLTVNRVDADSFSVNVIPHTAVKTTLEHLRPGDRVNIETDILGKYIERLLGGGTEPSKGDGGVTLELLAKNGFL
The following text describes a protein:
Function:
Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells. Binds both phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate; the resulting conformation change is important for the release of the bound alpha-tocopherol (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MLVLVLLQSTLFATVAYASKQHGFSTAVVRLENMLLFESRLIDEIRQYITDTDGASEDLRRYVEDFEHNILRPGFADLAYHARHPVGAYRLVKRLSQTDSRILKHAQLLTGVGVARDGDDVIKISELPTEEDLRMSALALARLQDIYHLDLRSLTRGQLVMLSRQSDGTVVKQKRLSRVEPTFTLEAEDTVYIGDMAYNEEDYLNAVLWYLITLDLTEGKEMADITDDTANDSAPGRVQVLVKLGDALTKLQQHQRALPFYNEALQLEPNNQEIKSKVVESERQVTLQGDVTVKMGKLLQGAIPYQQDYENLCYRSALQNQAPSSRLSCTFVRTSPQLYLSPAKMEVLHETSPEIALYHDVISDQEAAMMRELALKELKRSPVVDKNGKAFLSNFRVSETGWLHDNTTELISKLSRRVSYITGLNTEYPSAESFQVVNYGLGGLYVPHVDYFEEDQVRHMKRPDNRILTFLIYLSEVEAGGATVFPQINLIVPAVKNAALMFRDMKRSGDFEPLSMHAGCPVLIGSKWIANKWILDRGNEFRRPCGLTPEE
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSIEKRVKEIVAEQLGVDEAQVTNDASFMDDLGADSLDTVELVMALEEEFDIEISDEDAEKIQNVQDAIDYITEHT
The following text describes a protein:
Function:
Vacuole membrane protein that recruits ATG8 to facilitate the degradation of vacuolar integral membrane proteins during early-stationary vacuole turnover (EVT) when cells enter stationary phase.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MDNEIVALCGFFVAIALVLSCISIITHLKNYKKPVLQRSVVRILMMIVIYSSVSFLSVYNEKIGSIFEPFREIYEAFALYCFFCLLIDYLGGERAAVISLHGHLPRPRLWPLNYLQDDIDLSDPYTFLSIKRGILQYTWLKPFLVIAVLLTKVTGVYDREDQPVYASADLWIGLVYNISITLSLYSLTTFWVCLHEELAPFRPFPKFLSVKAIIFASYWQQTVLSITNWLGLLNGTGWIYSLLNQNVLMCLEMPFFALSHWYAFRIEDYDTPTWLSCARLPLLKAFKDVIGLKDVWCDSLQTLHGDRYVYQNFEPGENLIPSRNDGRINRTSHGLRYSQGGQSKYWISRYDQSRVRLINNSQNSPQSNKSYFSIPGMSTSHFENGLQFEIDDEMEPLYNQAKQMRYGDYNYPVLLVNNTHASSSYT
The following text describes a protein:
Function:
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
Sequence:
MQANDRPRTFHLTVAYDGTEYCGWQVQPEQRSIQSELERVIRPLAGRPVRVLGSGRTDAGVHAIGQVARCVLPVWKADTVALQRAINSKLPNDIRVKAVRETRERFHPIADATGKQYQYLVQVGGSRDPFANRFVNRVGGPIDHSAMQSAAAKFVGRHDFKAFQGTGAERPSTVRTIHSARWIPRVATGPTGAELEGEHWCFEIDGEGFLYNMVRNLMGTMLEVGRGKKSPNWIDEVLASRDRKMAGPTAPPQGLFLCRVDYPDEVFQVEEPDVIE
The following text describes a protein:
Function:
Catalyzes the 2'-O-methylation at nucleotide C1920 in 23S rRNA. Enhances motility. Enhances biofilm formation. Involved in the assembly of 70S ribosomes. Involved in virulence by promoting adherence and invasion to host cells. Involved in pathogenicity by modulating secretion of host-protective chemokine interleukin 8 (IL-8). Involved in susceptibility to antibiotic capreomycin.
Sequence:
MRFDFFVSKRLNISRNKALELIENEEVLLNGKSFKASFDVKNFLENLKKTQDLNPEDILLTDGLKLDLLSEIYVSRAALKLKNFLEENGIEIKHKNCLDIGSSTGGFVQILLENQALKITALDVGNNQLHLSLRTNEKIILHENTDLRTFKSEEKFELITCDVSFISLINLLYYIDNLALKEIILLFKPQFEVGKNIKRDKKGVLKDDKAILKARMDFEKACAKLGWLLKNTQKSSIKGKEGNVEYFYYYIKN
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MDSNSLANRLGPQGNTGNTGSGRGGGGGGRGRSGRGGGRGRGRGGAGAGRGRGRGPRVGLAGASEQQSPLTATASSSVVATPDETPAASGTNTPTWTPKPIAPGTDAAVYLTENKFADLKGSVDDRLLSAIPFPTMSAVQAATLSTALSGKDVLAQAKTGTGKTLAFLIPSIHKLCALPKPPPQTSISVLVLSPTRELALQIEKEAHMLLANLQGTFGVQHVVGGTNIGAERKRLQKDRKDILIATPGRLLDHLSSNNSGLDLRRACQNLRVLVLDEADRMLDMGFRNELEKILKMLPDPVASERQSLFFSATIPSFVHEVAKLRPDHAFISTLTEQDTNTHEHVPQESLICSLRDCLPRALQVVLSEAVGYPTNHKILVFLPTARSTSLAAAVFTQLRNQKNSAYAKLGPIFEIHSRKSQAVRTKTMETFQTRASGILFSSDVTARGIDIPGISLVLQLGLPSSLEQYIHRLGRTARAGKQGRGVLILADFEAFFLNQQDVKKLPITKLDVAAVETESRVTLPQVATDVDGAMQTIDSTTRSQAYQAHLGFYKAYLKQLKWTSEQLIASTNDYARHILQWPADPSGTWVGPPLLQKTVSMMGLKGKPGLNIVKELPAKTNAGGRGSAGNELKRHGQTQGGRQANKR
The following text describes a protein:
Function:
Cadmium transporting P-type ATPase which plays a critical role in cadmium resistance by extruding intracellular cadmium. Capable of high affinity copper ion binding, but not active copper ion transport. May play a role in copper resistance by chelating and sequestering copper ions.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKPEKLFSGLGTSDGEYGVVNSENISIDAMQDNRGECHRRSIEMHANDNLGLVSQRDCTNRPKITPQECLSETEQICHHGENRTKAGLDVDDAETGGDHTNESRVDECCAEKVNDTETGLDVDSCCGDAQTGGDHTNESCVDGCCVRDSSVMVEEVTGSCEAVSSKEQLLTSFEVVPSKSEGLQSIHDIRETTRCNTNSNQHTGKGRLCIESSDSTLKKRSCKVSRQKIEVSSKPECCNISCVERIASRSCEKRTFKGSTNVGISGSSSTDSLSEKFFSEQYSRMYNRYSSILKNLGCICNYLRTLGKESCCLPKVRFCSGEGASKKTKYSYRNSSGCLTKKKTHGDKERLSNDNGHADFVCSKSCCTKMKDCAVTSTISGHSSSEISRIVSMEPIENHLNLEAGSTGTEHIVLSVSGMSCTGCESKLKKSFGALKCVHGLKTSLILSQAEFNLDLAQGSVKDVIKHLSKTTEFKYEQISNHGSTIDVVVPYAAKDFINEEWPQGVTELKIVERNIIRIYFDPKVIGARDLVNEGWSVPVSIAPFSCHPTIEVGRKHLVRVGCTTALSIILTIPILVMAWAPQLREKISTISASMVLATIIQFVIAGPFYLNALKSLIFSRLIEMDLLIVLSTSAAYIFSIVSFGYFVVGRPLSTEQFFETSSLLVTLIMVGRFVSELARHRAVKSISVRSLQASSAILVDKTGKETEINIRLLQYGDIFKVLPDSRIPTDGTVISGSSEVDEALITGESMPVPKKCQSIVVAGSVNGTGTLFVKLSKLPGNNTISTIATMVDEAKLTKPKIQNIADKIASYFVPTIIGITVVTFCVWIAVGIRVEKQSRSDAVIQAIIYAITVLIVSCPCVIGLAVPIVFVIASGVAAKRGVIFKSAESIEVAHNTSHVVFDKTGTLTEGKLTVVHETVRGDRHNSQSLLLGLTEGIKHPVSMAIASYLKEKGVSAQNVSNTKAVTGKRVEGTSYSGLKLQGGNCRWLGHNNDPDVRKALEQGYSVFCFSVNGSVTAVYALEDSLRADAVSTINLLRQRGISLHILSGDDDGAVRSMAARLGIESSNIRSHATPAEKSEYIKDIVEGRNCDSSSQSKRPVVVFCGDGTNDAIGLTQATIGVHINEGSEVAKLAADVVMLKPKLNNILTMITVSQKAMFRVKLNFLWSFTYNLFAILLAAGAFVDFHIPPEYAGLGELVSILPVIFVAILLRYAKI
The following text describes a protein:
Function:
The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane. Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus.
Sequence:
MQRQLAGLALTDVSGAAIYAQCYDPLLAEGYLSSFLPALHAATLDSISTSSQLHYCPYPCIYRKLGGLFLFVIGAEAENEMLLCDIASTVVEALVGILGERLSLAACKEQYASICITLGEIVDNGFYLSDNPAGPQVSERSFKQTLSDGARFLLGALMN