lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.
Sequence:
MNKCIPMIINGMIQDFDNYAYKEVKLNNDNRVKLSVITESSVSKTLNIKDRINLNLNQIVNFLYTVGQRWKSEEYNRRRTYIRELKTYLGYSDEMARLEANWIAMLLCSKSALYDIVNYDLGSIHVLDEWLPRGDCYVKAQPKGVSVHLLAGNVPLSGVTSILRAILTKNECIIKTSSSDPFTANALVSSFIDVNADHPITKSMSVMYWPHDEDMTLSQRIMNHADVVIAWGGDEAIKWAVKYSPPHVDILKFGPKKSLSIIEAPKDIEAAAMGVAHDICFYDQQACFSTQDVYYIGDNLPLFLNELEKQLDRYAKILPKGSNSFDEKAAFTLTEKESLFAGYEVRKGDKQAWLIVVSPTNSFGNQPLSRSVYVHQVSDIKEIIPFVNKNRTQTVSIYPWEASLKYRDKLARSGVERIVESGMNNIFRVGGAHDSLSPLQYLVRFVSHERPFNYTTKDVAVEIEQTRYLEEDKFLVFVP
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MVSRVESVIVFALYKFLQRYFHSFHCFFLLCFTVMLCVVQQCSSAMTSFRCPTFSLSKYTCVLPASIPEMILFTFSSHTFQTPTKKGNKTKKKRKKEKKKETIVEKNKVLKSFALYKKINNYRSTRCVLVCQCKY
The following text describes a protein:
Function:
Might have DNA-binding ability.
Subcellular Localization:
Nucleus.
Sequence:
MFLEVADLKDGLWVWKVVFLQVCIEASGWGAEVRDSCGCGDSSSHQTDDPATALALHVACHSFKGQLVQQTLLLGTRPRVWVNNIPQEGPSLPLRQWLLPQCPSLNRSGSAMGTGWGLSGLSPTALSRDGYETETPFSPEGAFPGGGPAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGSQEKPTFVVQVSTEQLLMSTGGCDKEPPRGQGVDTRGDRTQEGGEKPREQREGPRPEQGPDIPGQQEESPQQEPSSERGDSVGEREARSPGHEGEGGGEWPGISGERRESPGEWGADVPRGRGEGAGEWGSDVPKDRGEGGREWGPEAAQEHGEAARDWTSESPRTLGEDARDWGSSSRDAAGSSPCALRGSLAPERLGDGPWPAWPSPQEREPGPRDRVESPREWGGTESPRGWEAGPREWGPSPGGRGDGPRRRPRKRRGRKGRMGRQLETTATSASATGGPAEEAGASAPEGQAGGGPRGRARGPRQQARRRHGPQRRRGPPQAGEEGPGDATLVLGLGTTSGEQRADQSQTLPALAGAPTAHAHAVPGPGPAAATLGGRGRRGSWRGGRRGGGAGASGGGRGGRGRGRGGRRGSGLSGTREDAGSPSARRGEQRRRGHGPPAAGAAQVSTRGRRARGQRTGEEAQDGLLPRGRDRLPLRPGDSNQRVERPGHPRGGHGAINAPSAPDASPPHHPRRWVSQQRQRLWRQFRVGGGFPPPPPTRPPPVLLPLLRLTCAGDPGASRPGSRRPARRPRGELTPQRPSPFAPQEEGLRAESCVDDGAIAPDTDTASGEVPEAGPSLSSTMCQMGRPRPSPKSPR
The following text describes a protein:
Function:
Transcriptional activator. Participates in neural induction (By similarity).
Subcellular Localization:
Nucleus.
Domain:
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
Sequence:
MYSMMMETDLHSPGVQPPSNTGQTGGGGGNKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLHAAGGGHMGVGLSPGGGGGGTGGVVVQRLESPGSGASAGGYAHMNGWANGAYPGSVAAAAAAAMMQEAQLAYSQQQQQHPGSGGHHPHHHPHHPHHHPHHHPHHNPTPHPPPPPPQPMHRYDMSALQYSPLPGAQTYMTASPSGYGALGYSSSQQQHQGSPSSAAVAAAAAAAAAAAASSGALGALGSLVKSEPSVSPPVSGGGPHNRPPCPGDLREMISMYLPSGGEAGDPAAAAAAAAAAAAAATSRLHSLPQHYQGAGTGVTGTVPLTHI
The following text describes a protein:
Function:
Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
Subcellular Localization:
Secreted.
Sequence:
MFKYVIPLCALTLAAPSFAAQTTLMLSQKSDVNYLGWSTDESKVARQEVYRGTTSNPDLRERIAVLDAETRTFKDADTNSGLNYWYWVDVVSENQAQVVSNAVTTAPNAGPLRAAKASSECKPGATFENRTVDCGGVTIGTSCPNDSDKQKPLIILKNATVKNLRISASGGADGIHCDSGNCTIENVIWEDICEDAATNNGKTMTIVGGIAHNAKDGYGGKPDKVLQHNSKNSTTVVKGNFTLTGEHGKLWRSCGDCSNNGGPRFLTVTSATVNGTIDSIAGVNRNYGDVATISGLKIKNYKEGKPPVCEEFKGVVKGQGSTEKYGEKWDTTNCKVSRSGVSKL
The following text describes a protein:
Function:
The rhoL-rho operon is regulated via attenuation by Rho-dependent terminators within the sequence coding for the RhoL leader peptide. It has not been determined if translation of rhoL is required for this Rho-dependent termination to function.
Sequence:
MRSEQISGSSLNPSCRFSSAYSPVTRQRKDMSR
The following text describes a protein:
Function:
Part of the Zra signaling pathway, an envelope stress response (ESR) system composed of the periplasmic accessory protein ZraP, the histidine kinase ZraS and the transcriptional regulator ZraR. The ZraPSR system contributes to antibiotic resistance and is important for membrane integrity in the presence of membrane-targeting biocides (By similarity). ZraP acts as a modulator which has both a regulatory and a chaperone function. The zinc-bound form of ZraP modulates the response of the ZraPSR system by inhibiting the expression of the zra genes, probably by interacting with ZraS (Probable). Also displays zinc-dependent ATP-independent chaperone activity in vitro and protects malate dehydrogenase (MDH) from thermal aggregation and denaturation.
Subcellular Localization:
Periplasm.
Sequence:
MKRNNKSAIALIALSLLALSSGAAFAGHHWGNNDGMWQQGGSPLTTEQQATAQKIYDDYYTQTSALRQQLISKRYEYNALLTASSPDTAKINAVAKEMESLGQKLDEQRVKRDVAMAQAGIPRGAGMGYGGCGGYGGGYHRGGGHMGMGNW
The following text describes a protein:
Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKWLRSAEMEYISLIVNEDAAHDCVQKLGDLGVLEFTDLNPELTPFQRRYVNYVKRCDEMERKLRYFEVELAKFSITPKPAGSIDQFLAGSADIRYGSQDTAARALDTLERLLEDKEQELLQLNSMHEKLTREYNERKELQEIISRAGEFFEIEIPEVQARRTSRTGSRSGGYSFVEASAGAGGEDSSTLRFRNVTGVVPADERLKFERMIFRTTRGNCFTRFSPIEEPLADPTNGQPVTKHAFVIFFQSTFIENKLRKICDAFHARLYSLPPMDDRAAIAHLIQSNAGELNQSSHILRRNRESCVLLCRDLAETLESWKWSVLQEKATYHALNMFRADVSGMLRAEGWVIKEALSSVRRAVTRAHTAADDKSMPSLVDSVAKPWPVPPTYFETNKFTDAFQAFVETYGCPRYREVNPSVFTAVTFPFLFGVMYGDIGHGLCVLLFGLYLILTERRLEHPGSMGEMTASIYGGRYMLFMMGAFAMYAGLIYNDFFSLPLNLFGSKFAYPDCLESHDREAKCVAEYIIDGKMTYVNATDVSAGDNVYAMGLDPVWKTSSNELLFFNSFKMKISVIFGIIQMTFGILLKGWNNIYFRDYSTFFFEFVPQIVFAVSLFCYMIVLIVMKWSINWTERMKHEVCPYNYAGEHTGCRPPSLVNTLINIALAPGNVVDPLYEGQLETQQTLLMMAFVSVPAMLLIKPIYLKIQHDRTAPPVSHHVDFDDEAEERLVTQHHGNSGGHGGHGEEFEFGEVVIHQGIETIEFVLGMVSNTASYLRLWALSLAHSELATVFWEKTMLSTINSDSFIAIFIGFGVFAATTFGVILAMDVLECFLHALRLHWVEFQNKFYKADGYKFHPFSFKQTIKDSQQV
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MFAVKGLKVSTDKLKVETEHGSVLATQPPRTVAAGEEGASAPKPKNKKRKRAGRSNNTDVNLDNVADLWEKVIEGGDAKAKKAKEDAKKEAHKAKKQKTEEGTTAEATTTTAAPQPATDKKNNNKKNKNKSKQESKPAAAAAEKKQDATTTTTTTTTTTESKPSAPAPAPAPAPAAPKLTPLQAAMREKLISARFRHLNETLYTRPSRDAFSLFSDSPEMFTEYHEGFRRQVDVWPENPVDGYISAIKTRGKLRNAPRSRPGGADGSTSSDGTKYPLPRDRNGLCTIADLGCGDAKLAQALVPLKRKLGIEVKSYDLQDGGKPELITRADIANLPLKDGSVDVVIFCLALMGTNWIDFVEEAYRVLRWKGELWVAEIKSRFVDPTRKKGGGPGNVVSHSVGNRRKAGAATAAGPGPALGKKDKAKMKEEEEAEEEQQLAVHVDGVELRQQETDVSAFVEALRKRGFLLQREYGQKAVDMDNKMFVKMHFVKAMPAIKGKCADLKKEALKTTQTDAKGRPIKTPKFIDADEEASFNENALLKPCVYKIR
The following text describes a protein:
Function:
Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR (By similarity). Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen without producing the toxic Cr(5+) species and only producing a minimal amount of reactive oxygen species (ROS). Chromate reduction protects the cell against chromate toxicity, but is likely a secondary activity. Can also reduce potassium ferricyanide, 2,6-dichloroindophenol, V(5+), Mo(6+), methylene blue, cytochrome c and U(6+). During chromate reduction, is able to use both NAD or NADP equally well.
Sequence:
MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIADIPLYDADVQQEEGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLPDQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQTGEVIDQGTLDHLTGQLTAFGEFIQRVKI
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
SGTWRRVRCGRCSVCSAYWPPGLCQRAGAEQPLWVPLRPGKVLGANEEPVSRGWLHPFSTATQRTAGEDCSSEDPPDGLGPSLAEQALRLKAVKLEKEVQDLTLRYQRAVADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADILEKTAECFSDGAEPQDHKLTLEKVFQGLSLLEAKLKSVFTKHGLEKMAPIGDKYDPHEHELICHMPAGVGVQPGTVALVRQDGYKLHGRTIRLAQVEVAVESQRRL
The following text describes a protein:
Function:
May act as a specific coactivator for the mammalian TEFs.
Sequence:
MAVTNFHYITRMSSGFKVYILEGQPNLRSEDRFRHMTSDRVRMRPAHPMKRKHSSDRGRTLEERRERALSKCVANSARRSSGFSIPESPTSTWSPTASPTHLIPSPVFSSPVMDEPLALIKKPRPEPEKTESQNKATTQIQMRPSVITCVSSASRSTKQDCCNHSTAVSKHSYDHVEEHFQRSLGINYHRATSISVSVDDHFAKALGDKWLQLKASSSSCHSSSSSSSSSPPSSPTFIHSPGYSPKRARKDSSSPTTTTPNFWSDK
The following text describes a protein:
Function:
Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
Sequence:
MPGIAVLLSGSGSNLQALLDAQAAGDLAGEVVLVASDRAQAYGLQRALQAGVAAAYIPLRATRGPQRQQWEQRLADIVACFEPDLIVLAGFMRVLSAAFLERFPNRVINQHPALLPADGGDTVTTTSGLVIPALRGAHVVADALRLGLPVTGCTIHRVTPRVDDGPILARAEVPIQPDDTVESLHERIKAVERRLIVATVNRLLAGE
The following text describes a protein:
Function:
Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA), with a preference for leucine, methionine, serine, valine and to a lower extent threonine and alanine as substrates (can also use glycine), and epsilon-lysine acetylation (KA) of several plastid proteins.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MGHLPQSLYSAAGPKFPYPGSSGLGVDQRKLTWSRFPVFLRCASTESLTSLTQNNAAEIELKYLVSQHGWDVRRLNRDDEDEIRRVSLVQAEAFHIPLALFDDFFFMFFQAEVLSALLYKLKNSPPDRYACLVAEQTSETETLSSSSVVGVVDVTAQTESSVLRYFPGVEEYLYVSGLAVSKSQRRKKMASTLLKACDVLCYLWGFKLLALRAYEDDAAARNLYSNAGYSVVETDPLWTSTWIGRKRRVLMSKRFS
The following text describes a protein:
Function:
Antitoxin component of type II toxin-antitoxin (TA) system VbhT-VbhA. Acts by inhibiting the adenylyltransferase activity of VbhT; competes with ATP-binding and prevents productive ATP-binding to VbhT.
Sequence:
MLSEEEIEYRRRDARNALASQRLEGLEPDPQVVAQMERVVVGELETSDVIKDLMERIKREEI
The following text describes a protein:
Function:
Component of the monoterpenoid pyrethrins biosynthesis; pyrethrins are widely used plant-derived pesticide. Acyltransferase that catalyzes the esterification of terpene acids and lipid alcohol substrates into pyrethrins; mediates the transfer of a chrysanthemoyl moiety from the coenzyme A (CoA) thio-ester chrysanthemoyl CoA to pyrethrolone, and, to a lower extent, to jasmololone and cinerolone thus producing pyrethrins (e.g. pyrethrin type I). Can also use pyrethroyl CoA as substrate. Also has esterase activity, being able to cleave the ester bond of pyrethrin I, p-nitrophenyl butanoate and p-nitrophenyl octanoate to produce pyrethrolone and p-nitrophenol, respectively.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MAVASRKLGALVLVAVLCLSLPTGCLSSQQAAALFIFGDSVFDPGNNNHINTHVNFKANFWPYGQSYFSSPTGRFSDGRIIPDFIAEYASLPIIPAYLEPNNDFTHGANFASAGAGALIASHAGLAVGLQTQLRYFGDLVDHYRQNLGDIKSRQLLSDAVYLFSCGGNDYQSPYYPYTQEQYVDIVIGNMTNVIKGIYEKGGRKFGVVNVPLIGCWPGMRAKQPGNTCNTEVDELTRLHNQAFAKRLEQLEKQLEGFVYAKFDLSTAILNRMKNPSKYGFKEGESACCGSGPFGGNYDCGRIKEFGLCDNATEYFFFDPFHPNELASRQFAEMFWDGDSMVTQPYNLKALFEGKPSTKYLPNDEL
The following text describes a protein:
Function:
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Sequence:
MGSQSSSGMSGGRGSSSGNPAEQSEAAEPNQSSSRGRRTADRQQGEEGQSASEEDVDLAEVLAYLLRRGQVRLVHGSGATGLQLVQSHSDSDDESEGAWDGRLGDRYNPPVDTQPDTHEIDSSEIRTQILLATASSSLKSRHSFTYMLTEREQGRCRGSSFSHGECSRIRTHFLPNHVSHKDTYQQKAFCGVYSEDGNLFLSACQDQVIRLYDTSKGRFHLQRTVRARDVGWSVLDVCFTPDARHVLYSSWSDYIHLCSIDGDSENHTALDLNPDERRFCVFSLTASTDGKEILGGANDGCLYVFDLEQNRRTLKIDAHEDDVNAVAFADSSSQLLFSGSDDALCKVWDRRTLREDRPQPVGQLAGHRDGITFIHSKGDARYLISNSKDQSIKLWDVRKFSPKEGLAASRLAVTQQNWDYRWQQVPQRALKKHKLTGDTSVMTYRGHGVLHTLIRCRFSPEFSTGQRYIYSGCSTGKIIIYDVLSGAVVSRLLGHDACVRDVSWHPYEASIISSSWDGAVRMWEHRQTHPLEEDREREHNRQ
The following text describes a protein:
Function:
Specifically hydrolyzes the glucosidic linkage in glucosylceramide. May prevent accumulation of aberrent glucosylceramide containing immature ceramide (By similarity).
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MTHPDRSAHDLNVPIQHSGRWFQDNLGRTLLLRGINVCGSSKLPTRPYPGSTHLYDDILFWDHRNVSFVNRPFPLEDAHEHFSRLSAWGLTLIRLLVPWESIEHEGPGCYDEEYIDYLRQLIEMMPRYGIKCIIDPHQDTWSRFSGGSGAPGWTFEVAGLNIKHFKETGAAYVHNTNAVPGDPLPMVWPTNYTKLASCTMFTLFFAGDTFAPHRTYQSQSIQQFLNHHFIEAYRHLAERLSDLEAVLAFEFMNEPHPGYIGLDHLDSFDPIMNLLFGDSPTPLQSFALGDGIPQTVDVYIKSWPFPTKKSHDRVINASQTSAWFSGCVWKEHGVWTVDDQGVPRLVNTHYFSKHPKTGEKISFYEDFYKPLVNRYVAAIQSVKKEYYCLVEPLANEKPPVYNEHDHHHNVIFSPHWYDLDSVFYKKFNARMTHDVQCLQRGGNVFSATYFGKRGAKKNYRGQIKNIKEDGLLNMGEKPCIMGEVGIPMDLNNKMAFEDDNYENHVHFMDAIIYALETNLISFTLWNYDVFNDHEYGDHWNGENFSIYSVKKSEEDYMRHDDGNSKLSKKHLYDGGRVLEAVLRPYAAKVAGTPVSAEFNIDTLQYTFSFIPDCKGSTTTEIFVPYFHYGNKTIKTDVSFGRCSYIEEFQTLYHQYELNDPLPKLVTITMGILTTESANSCSVM
The following text describes a protein:
Function:
Presilphiperfolan-8-beta-ol synthase; part of the gene cluster that mediates the biosynthesis of botrydial. Botrydial is necessary for colonization of plant tissue by the T4 strain. It is a strain-dependent virulence factor since highly aggressive strains like SAS56 or B05 still retain substantial virulence when botrydial synthesis is impaired, since they produce also botcinic acid. The first step of botrydial biosynthesis is performed by the sesquiterpene synthase BOT2 which catalyzes the cyclization of farnesyl diphosphate (FPP) to presilphiperfolan-8-beta-ol (PSP). The cytochrome P450 monooxygenase BOT4 then catalyzes the hydroxylation at C-4 to give a probotryane intermediate. Acetylation of the hydroxyl at C-4 is carried out by the acetyltransferase BOT5, followed by the combined action of the P450 monooxygenases BOT3 and BOT1, to yield finally the glycol, via the regio- and stereospecific hydroxylations at C-10 and C-15 of the probotryane intermediates, respectively. The cleavage of the C10-C15 bond of probotryane skeleton is an intriguing and chemically important reaction, which could be mediated by some of the monooxygenases or by a combination of them. It is possible that either BOT3 or BOT1 would oxidize either the 10- or the 15-hydroxy group to the hydroperoxide derivative, which would then undergo heterolytic fragmentation to give the dialdehyde botrydial. Finally, the dehydrogenase BOT7 might be involved in the conversion of botrydial to dihydrobotrydial.
Domain:
The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
Sequence:
MAIPALEPQLHDADTSSNNMSSNSTDSGYDTNSTTPLEKSEKPNTQELKQQQLDPKRPPFVRVPDLFGSIMSTKPVVNPNYFAAKARGDRWIARVMNFNKAVAARNSKVDLCFLASMWAPDAPEDRLVMMLDWNHWVFLFDDQFDEGHLKEDPAAAAEEVKQTIAIMGGNAPRYTAESNPIRYVFQQCWDRLKAVSSQEMQQRWIDQHKRYFDQLLVQVDQQVGGENFTRDVEAYMDLRRGTIGVYPAISLSEYGAGVNVPQHVYDHPSLQECMKVSADLVTLVNDVLSYRKDLELGVDHNLMSLLMQRDNLSAQQAVDVIGDMVNECYRRWYLALAELPSYGEKIDYNVMKFVEICRAVAQGNLYWSFQTGRYLGPEGHEVHETGIMYLPPAANLVVA
The following text describes a protein:
Function:
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQLMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MHRLTTEKCAYFRNLLVDTCRLAIRLSQWCCTAPYPLDPYQHIKPYQQSKSFQTINILRRLLAALLFGIALSVPFLLYFLKADHVNAFKIPLSIRLMFYLQALLQMGSLSYVLLVYQFRSSFHRFYFDRLVCVLEHFGRRDIDKSLSALQTNMCRLLIASLVFVTLVFSALVVRDHSWSNLLKVVIYLATQLMATSFTLQYLTVFGIVAVLLRQMNDTLELILYGTVVYDEGTNGSHSRLRTPVRFTRDDEQTIEKIRLLQLKLVQIVFHTNGGEYGLLLIVVLLTTFIFLNTELLQLYQGIKASAFTFDVIGAKLTNSALKFAMMVAYAIANRTIQTQNLRGLKLLFQLHSSSSSSRCHEITNRFISQTTLFLANGHEAYSMISIDMTLILSIVAGLTNILVVLVQFSDGKPSCN
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MSIQYGRVVSLILLERFGPVVEKVGTYLFQYGTVPLLYIKKHTDLPISKVKEALCILIKYRLVTFTPNRNENVANYTLQHERVLLMLRYAKYINLIKKKFGTECELIMEELLQRSYWTASELILKVIERLKKDHNKNVTILALREKIFSLLAAQYLIRLPYSMEDKPVPSLVIKETEQFSPPTIDFKQIALVQSNKAPVDSLPDQGVYWTVNFDRFHQDMRDKLIVNAFIKKFDENAGEFVRLLLQQMYIRTQPWAEVSNPVPIVEIRDLVRKQATHQHLLAFFDQYVNVLEQDSSKLIRQSGEAGGGSFQIFLKETFTQFAWETVEQIVLEKFDTKAARIFRLVKSKQYIEPDQIQQLAMIPAKEAKRLSYQLLEENFLQVQDLKKSTSNGPNKSFTLFYTNLDQIVRMTLELCYKTLFNIMTRKNHERLVHKRIIDKKQRVDTIIMGMRAQGAADEQLSDIEEMITPPEREILQKIDVIMKKLNTVELEVDETIFLLQMYLIYQ
The following text describes a protein:
Function:
Involved in G2/M transition (By similarity). Required for pre-mRNA splicing and endoplasmic reticulum (ER) to Golgi secretion pathway. U2 snRNPs associated protein required for the pre-spliceosome assembly. The involvement in ER to Golgi secretion is probably indirect and due to the splicing of the pre-mRNA coding for SAR1, a small GTP-binding protein required for COPII vesicle formation from the ER.
Subcellular Localization:
Nucleus.
Sequence:
MWGGGKMAVVSLSPHTAKMRKLFGQASTTMAYDGLKREAERRTRSDHNITMVAKDDELYLYHLTLKKQTNFVHSCIGHFVDLEAGSKREQSQLCVATETHLELYDTADGELKLIAKFQNLFATITSMKSLDLPHSGSRAKASNWPTFLALTSDSGNLSIVQIIMHAGALRLKTLVNQPLTRTTLRRVSPISYMEIDPNGRCIILSSVEQNKLCFLVDYAQKLRISSPLEIIRPHMVTLDMAVVDVNFNNPCFVTLEIDNAATQLSVHLIFYVLELGLNHIVKKADYLVNPSANFVLSLPDLSRYNITTSLSDNNYDADYDTLFNPFVVIGFENHILVKDMNGFFSLKVEIPKRSITNSRHKNVTIISGIVQKLKNDFFVLLQSNHGDLFKLTVSPDTNDRNRPLVQLSYFDTIQNSHQLHIFKNGYLFALSEMNNNFLFQFEKLGVEKNDFSNVLTSKDPNKSLVFEPSIKLQNLSILSQQLNLNPSIKSQIVSDSPLSIATKHFTNNKIITLTNAVNYSNLISTSLPPNATKLWLIPDPATTGDNNTLLFITFPKKTMILQIDNESMEELTPDEATRSAFKLSQDTTIHTCLMGSHSIIQVCTAELRHIVPTGKSRYSNKLTWVPPAGIRIVCATSSKTQLIISLSNYELVYFKIDVSSDSLIELTTHPELDTMPSKVAIVQDTQHADLLAIADNEGMIKIMSLKDQKEDFLTVISLQLVSEKISDMIMVRDSSIGQLNLHVGLENGVYMKFHIGDVDGSFTDIKRRFLGLKPVSLSYLREISVSLNNEEEEEEEEDDDDEKEEEEINSSGAKWMSCVVCHSSSTWVSYTWKNVWTIRQLKDQNMLSCSKFVNADVAINGVCSISSSGRLNIGRVSNFPTLDNWFHVHESSVNKQENGGGDESNEEEEDEMEEEMEMLQISTFRPRTILSFPNNPKSILFIDNHSGKKQCRISLQIDGECLKFGSSDHLYKILDDIDCVSAAIIDFTRQADHLIICAGDKRLLTYKILVNKDKLSFDIELLHQTEIISPIHAMLKFKNFLLTAMGSTIVLYGLGKKQLLRRSVTQTPVSITKIVSMHQWNYERLAVGDIHESVTLFIWDPAGNVFIPYVDDSVKRHVTVLKFLDEATVIGADRYGNAWTLRSPPECEKIMSNHDPSELSNGAIKYPLDVITLQQKLPNTYDCKFKFQLLNHFFVNDIITDFHILDSLSNSDRPGCIYMGLQGTVGCFIPLLSKGNVFMMGNIENIMAEADDTFYLDYESRKKNNNMRKEDDEEESGSVVLQGRHGIEDEIICEGSCSILGRDHQEYRSYYAPVRKVIDGDLCENFLRLSLNEQEFLAKNLKSVQVEDIIQTINEVRTNYM
The following text describes a protein:
Function:
Probable transcription factor involved in abscisic acid (ABA) signaling. Required for the regulation of the cross-talk between NADPH oxidase, hydrogen peroxide and MAP kinase in ABA signaling. Regulates the expression of the NADPH oxidase genes RBOHB and RBOHE, and the MAPK genes MPK1, MPK4, MPK5, MPK7 and MPK14. Regulates ABA-induced hydrogen peroxide production and antioxidant defense. Required for tolerance to water stress and oxidative stress.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing ZFP36 display enhanced tolerance to drought and oxidative stresses. A natural allele in the promoter of ZFP36 in the durably resistant rice variety Digu confers broad-spectrum resistance to rice blast (Magnaporthe oryzae).
Sequence:
MTAALQALLDPTALSLGLPTPAINKEEYLAICLAALACTRAGKALVGVGGQQQVQACNKWLCPAPAAPEELRFRCTVCGKAFASYQALGGHKSSHRKPPSPGDHYGAAAAAQQLASAGDSKEDSASSAAGSTGPHRCTICRRSFATGQALGGHKRCHYWDGTSVSVSVSASASAASSAVRNFDLNLMPLPESTAAAGIKRWAEEEEVQSPLPVKKLRMSN
The following text describes a protein:
Function:
Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway. Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production. Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect. Enhances Notch signaling pathway in a non-cell-autonomous manner via direct interaction with NOTCH2. Also promotes Notch signaling pathway in a cell-autonomous manner through inhibition of cis DLL1-NOTCH2 interactions, which promotes neuronal differentiation (By similarity).
Subcellular Localization:
Secreted. Cytoplasm.
Sequence:
MCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPETVRRGTELWERDREVWNGKEHDEN
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. May play a role in mitotic spindle formation and/or function.
Subcellular Localization:
Nucleus, nuclear pore complex.
Sequence:
MSKRGADHQLTKDQDDSDDDRHGPVEVPKEASADVMATRKIAKPKSRKRPTSGVSSPGIFANLAAKPVSLPASTTQFTFGKPAVTANNDSDIHLKKRGLNKSFIDAVIKSVDNNPFGNLSPLFDEYRQHFSSIEKKPAEEQPTSNAVVSEVNPQQQKSQDSSSFVTEKPASSEKEDKEKPLVPPGAPRFGFSAPALGSSFQFNSSAFTPKGSFGEKSATEAEAKEKETSSNQTATGTAATTTNQFSFNTAANPFAFAKKENEESKPLTPVFSFSTTMASADASKETKQTHETKDSKSEESKPSNNEKSENAVEPAKGNTMSFSWTPDKPIKFDTPEKKFTFTNPLSSKKLPASSDVKPPSAAAVGFSFGTTTNPFSFAAPKSSFPTSSTPASVGAEKSEETSNGNKSEQEEKENGNDETRSNDSLVSGKGKGEENEDSVFETRAKIYRFDATSKSYSDIGIGPLKINVDRDTGSARILARVEGSGKLLLNVRLCQDFEYSLAGKKDVKVPAASTDGKSIEMYLIRVKEPSTAEKLLAELNEKKVSKSEN