lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
DNA polymerase II participates in chromosomal DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MSFRKGVENTGKFVPEKESDAAKRREDSSELRYQRSVLNDEVDAKFGFTRYKESAERIGWLINFHPVSLPCQPYFYIMTKKDCERDVMMYLTKKFVGRVQSVEIVVKEDLDLPNHLVGLKRKFLKLSFSTVEALIKVKKDIKPFVRRNRASCGSNQYDSNSLDSNKLTDHMENIIDIREHDIPYHVRVSIDLKLMVGRWYSISSANQEMPIIKIMEDLVDVPDPIVLAFDIETTKLPLKFPDSQVDQIFMISYMVDGQGYLICNRDIVSEDVEDFEYTPKPEFEGPFIVYNEPNEASALQRFLDHILDLKPNIFVTYNGDFFDWPFIEARCVANNLDLYRELGFQKETQSGYLSRACIHMDCFMWVKRDSYLPVGSQNLKAVAKAKLRYDPVEIDPEDMCRLAAEQPQVMANYSVSDAVATYYLYMKYVHPFIFALCTIIPLEPDEVKTDIKRKLAVLRDSSIRSENPIIYHLDVAAMYPNIILTNRLQPPAIIDEASCAACDFNKVDAKCLKKMFWTKRTEFMPASRSEYSRIQQQLENERFPPLTPGGPSRAFHQLPPEEQASIEKRRLAGIEDTNSKDLLRLRKAFLMTFAVWKNKVVEAEKKGDASELKRANALLVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGVVCHTGANIITKAREIVEQIGRPLELDTDGIWCILPATFPENYVIKTKDPKKSKITISYPGAMLNVMVKEHFTNSQYHELVDKERLRYEVRSENSIFFEVDGPYKAMVLPASKEEGKKLKKRYAVFNFDGSLAELKGFEVKRRGELHLIKIFQSSVFEAFLKGTTLEQCYANVAKVADYWLDVLYSKAANMPDSELFDLISENRSMSRKLEDYGVQKSTSISTAKRLAEFLGDQMVKDAGLACRYIISKKPEGAPVTERAVPLAIFQAEILDWEYYIERLGSAIQKIITIPAALQGVHNPVPRIAHPDWLHKKLLEKTDIFKQKRINEMFVVKNKSDDIEDLMSSSSSHQGSSSSIVPVATVVSRKREAEDLTLSWREALGNPPPMGKSEAELQTWLEYQKKKWAFQIKQKKHRLKRARYDDGSLLGTGVGGVIRQTTSTIGGFLKKTARNVYDWPWQIIQLAETDQSGIFKIWALIGGDLHSFKLIVPRIFYVNQRTSKVEGEGSMWKRVNRLLPRSHPVFHLYEYSVPEHMYLEHINEINADLSSPDVEGVYETQVPLMFRALVKGSKQMLALFIPSSKKVSVFVTDTVRTNQMPNLNNMYNSERNNKLQEKNNNNNNNNNNNNNNNNNVPGAGYTFDIRVETDVKKVYRSLQRLLTSYKDEKKGPTYIAIQSNREQKYLTSSVSILNDFPLVSLLVPEEENMYGVLDWQRAGSKHMINSFLNSDAILNATLEQCRYLHVPLGNLNRDVTQFGCDLFYARHLLKHNHILWCSMTDRPDLGGKEADDCRLILGSDVNGFDRLTVNHPGCYSTICVELDIVSLAVNALIQSNKILDNEGTSALSSFEALISQTSIEDLVQSSLTAAVTSSAASAVTSSAAAATLSSSLALASYDDTALCFTAFRILKNMVHGWIQEVATNQNVYADQQIVHFYRWLRSPTSLLYDPALGKSLLNLMEKLFAQLMAEFNRLGSGVIFADATRLIVCTKKREITDALSYVDYITSVIRNKDLFQIVEISYRQCWQILLWMDKANYGGIKGVLPLVDSSDRDQSLANQSQAFSTNQNNSETDSAYNNRNSIDDNINDDTMDEDNTKCSYKKLIREEFGQKLFGITQKIKKKHSANQRSFIFPTLPGSHLHFTNPALEFVKSVCQILFLDENIKEEVTRLKRDLLKLIGIGEFSDQSEWRDPCLSYVLPEMICKQCNNIRDINLCRDPYVDNIGIWYCNQCKCEYDLEEIEMQLVQAVRQTLVSYTLQDLTCDRCKLVSATNLAEHCSCAGTFSTMQPTKNFKQLILTFLNISKFYNLAYLHETISWVISMSSGILN
The following text describes a protein:
Function:
Protein kinase which is essential for the initiation of meiosis and sporulation.
Sequence:
MVEKRSRQSSSSGSEFSVPPDVDNPPLSIPLKTLSDRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRSDFVNTNHITAPPPGGFWDDASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATAQELCEMPFFENTVASQVDARGNVTNTEQALIFAGINPVATNTKPIYFNSSTKLPAETESNDIDISNNDHDSHAMCSPTLNQEKLTLVEFLNEFVEEDNDDHSIPDVGTDSTISDSIDETELSKEIRNNLALCQLPDEEVLDHSLSNIRQLTNDIEIINKDEADNMEQLFFDLEIPEKDEFQRKQPFNEHADIDEDIVLPYVNNSNYTHTDRSHHRGDNVLGDASLGDSFNSMPDFTPRNFLIPTLKKSREKFEPHLSNSNQHFGNVTF
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
Sequence:
MELATESIEGVLLVDKPQGRTSFSLIRSLVRLIGVKKIGHAGTLDPFATGVMVMLIGRKFTRLSDIMLFEDKEYAAVAHLGTTTDTYDCDGKIVGRSKKVPTMDEVLTCTSYFQGEIQQVPPMFSAKKVQGKKLYEYARQGLSIERRFATVTVNLRLVKYEYPRLHFVVQCSKGTYIRSIAHELGNMLGCGAYLEELRRLRSGSFSIDQCIDGNLLDEPGFDVSPYLRDANGLILQPAPVL
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MSRIGSWLWLPLMLAVTLNHSHQHINALTLHTSRYAHQSHRVGRSQVKLYMTSTTTSWDKLTVPELKSQLKERSLPVSGVKAELIKRLQEHEASASPTSSPDDNQPSKKKTTSFPPPKDETEVQVIEKEVQETVRMLEGLKLGSSSQYVKIELQSTSGESPQQKQQKKMMKSLQDSLLQSQQQSSPSTNTEQSQPASPAQFARAERMKHHVEQLRQRPANELKEELASFRLANKGRKPDLVSRLAEYYVSQEMGDDTEGDLEDDDDYSEITSLPKSTFNAPKSLDKDVSISFAGIPRLSTTASNAIYQAFSSHDGKSTKQPEPTPIQSVAIPKLFYPPHPSALLHAPTGSGKTLTYLLPITETLWREVDSDEGIDANDMGNGVAIVLLPTRELAAQVAGVATVLAPRGMVRLVPRPMDLMNCWKDEGDRGEDFAYYEENEDVEDDAENAGEKYSPRILVGSAKSISVSLFGDGKMPGTPTSKPEGKRLLSCTRWVVMDEVDRLLNVKKTRTDKTNKRHEKPAAMLAAAISRLTLGRAQVIAASATVGRPLRRELSRVLGLHSSECPETLRGDDDSDRLEAKIKSSNEDDKHIGRAVKIPDTVRNYVLPVDGSTTGSLLTSAAFASKSLLNTQDQTESSKKVLVVLTRNCDIKVHNALGALRHFGIRPEPQSLLDALEADGTDRLMEAHRRVSGVVGVGGSKKRAKNDDNGYLLVTHEDNVRGLHLDGLDAVVVVGRPGSPDEYTHIAGRTGRAGQSGSVVSIVSFEQAAALASWSKMLGVDFLPLDETEVAGVLSD
The following text describes a protein:
Function:
Confers azacytidine resistance in high copy.
Sequence:
MNVTRLYFRVAGTKQFARYVHKYAAYSSTSFQKKKSHFPSPATLDHPDAGEDAFINLRNENYILNAVFDGVGGWANVGIDPSIFSWGLVREIKKVFNNSDEFQPSPLTLLSKAYAALKKSNTVEAGSSTACLTLFNCGNGKLHSLNLGDSGFLILRNGAIHYASPAQVLQFNMPYQLAIYPRNYRSAENIGPKMGQATVHDLKDNDLVILATDGIFDNIEEKSILDIAGVVDFSSLSNVQKCLDDLAMRICRQAVLNSLDTKWESPFAKTAKSFGFKFQGGKVDDTTITCLLIKSKNYE
The following text describes a protein:
Function:
Transcription activator that plays a regulatory role in gibberellin-induced stem elongation.
Subcellular Localization:
Nucleus.
Domain:
The QLQ domain and WRC domain may be involved in protein-protein interaction and DNA-binding, respectively.
Sequence:
MMMMSGRPSGGAGGGRYPFTASQWQELEHQALIYKYMASGTPIPSDLILPLRRSFLLDSALATSPSLAFPPQPSLGWGCFGMGFGRKAEDPEPGRCRRTDGKKWRCSKEAYPDSKYCEKHMHRGKNRSRKPVEMSLATPPPPSSSATSAASNSSAGVAPTTTTTSSPAPSYSRPAPHDAAPYQALYGGPYAAATARTPAAAAYHAQVSPFHLHIDTTHPHPPPSYYSMDHKEYAYGHATKEVHGEHAFFSDGTEREHHHAAAGHGQWQFKQLGMEPKQSTTPLFPGAGYGHTAASPYAIDLSKEDDDEKERRQQQQQQQQHCFLLGADLRLEKPAGHDHAAAAQKPLRHFFDEWPHEKNSKGSWMGLEGETQLSMSIPMAANDLPITTTSRYHNDE
The following text describes a protein:
Function:
Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.
Subcellular Localization:
Nucleus.
Sequence:
MMAAERRDGPLVLGSPRDTGSEPCMKRICPGLTCTVCGDISSGKHYGIYACNGCSGFFKRSVRRKLVYRCQAGTGCCLVDKAHRNQCQACRLKKCLDAGMNKDAVQNERQPRNMAHVRLDSVPSVTTAEPHELAASPLTRDPNPSSHSTSTSSSTSPSSSYGGPMSSASAHAAAFAFTANHRFMAGLMTAETCAKLEPEDALHDTCEIDVTGDTDPRVDLRSDHHHQRRPGMILSGSELASTPKEIAVYPSSNDSIYESSARLLFMAVKWAKTLPSFSGLPFRDQVILLEEAWSELFLLCALQWSMPLDSCPLLTGLHEQSQTDKAATCVSDIRLLQEIMSRFRGLRVDPAEFACLKAIVLFKPETRGLKDPQQVEILQDQAHMMLTQHIRAHQPAQTARFGRMLLLLPSLRFVTSDQVERLFFRCTIGDTPMERLLCDMFKN
The following text describes a protein:
Function:
Endonuclease that is involved in the suppression of homologous recombination and thus may have a key role in the control of bacterial genetic diversity; Acts as a ribosome collision sensor, splitting the ribosome into its 2 subunits. Detects stalled/collided 70S ribosomes which it binds and splits by an ATP-hydrolysis driven conformational change. Acts upstream of the ribosome quality control system (RQC), a ribosome-associated complex that mediates the extraction of incompletely synthesized nascent chains from stalled ribosomes and their subsequent degradation. Probably generates substrates for RQC.
Sequence:
MSDSTNLTIAEETLALLEWPRLCQHLSTFTQTPLGAIAARYLLPPSQWEESRELLAQTQAVESIENSPESNWHFKGIADITEPLARVERGGLVTGLELLAIAGTLAGVRRLRRVIEERDDLEILQTLVAEVRTLPELEQAIHHCLGEDGKVAERASPKLGEIRQKLKAVREQIQQKLQKIIQRQSNALQEAVITQRGDRFVLPIKAGYKEQMPGIVHDSSASGNTLYVEPQAIVELGNKLRQARRQEQTEEERILRQLSDQVLEVLLDLEHLLAIATRLDLATARVRYSFWLGAHPPQWLTPGDEKPITLRQLRHPLLHWQAEKEGGPAVVPITLTIDSQIRVIAITGPNTGGKTVTLKTLGLVALMAKVGLYIPAKETVEMPWFAQILADIGDEQSLQQNLSTFSGHICRIIRILQALPSGVQDVLDPEIDSPNHPIFPSLVLLDEVGAGTDPTEGSALAIALLRHLADQPCLTVATTHYGELKALKYQDARFENASVEFDDQSLSPTYRLLWGIPGRSNALAIAQRLGLPLAIVEQAKDKLGGFSEDINQVIAGLESQRREQEQKAANAQKLLQETEIFYQQVSQKAASLQARERELKSYQDQEVQQAIAAAKEEIAKVIRQLQRGKPSAQKAQQATEILGQIQAEQKAKVAPKPIGYQPTVGERIRIPSFGQTAEVTQVNATAQTVNVTLGLMKMTVPMADIESLNGKKVEPPPKSEPVPKKVKAEPPATEAKSPPVLVRTEKNTLDCRGDRLERAESRLEKALNQALDAGVLWIIHGKGTGKLRQGVQEYLSHHPLVKSYALAPQNDGGAGVTIAYLR
The following text describes a protein:
Function:
Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction (By similarity). Regulates epithelial cell proliferation and side-branching in the mammary gland. Required for neural tube closure and skeletal patterning. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 2. Isoform 2 may inhibit transcriptional activity of isoform 1 by interacting with it and retaining it in the cytoplasm. Transcriptional activator of EIF4G3 (By similarity). May also involved in behavior.
Subcellular Localization:
[Isoform 1]: Nucleus. Cytoplasm; [Isoform 2]: Cytoplasm. Nucleus. Note=Displays some nuclear localization when expressed with isoform 1, suggesting that it may heterodimerize with isoform 1 and shuttle to the nucleus using the nuclear localization signal of isoform 1.
Sequence:
MEDSDSAAKQLGLAEAAAVAAAAAVAAAAAAAAESEAEEPVLSRDEDSEEDADSEAERETRRVTAVAVMAAESGHMDMGTEALPSPDEAAAAAAAFAEVTTVTVANVGSSADNVFTTSVANAASISGHVLSGRTALQIGDSLNTEKATLIVVHTDGSIVETTGLKGPAAPLTPGPQSPPTPLAPGQEKGGTKYNWDPSVYDSELPVRCRNISGTLYKSRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMTLSGPVRLFVPYKRRKKENELPTTPVKKDSPKNITLLPATAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAQGDVFAGATVQEAGVQPPCRVGHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPSTPTKAVSPTVVSGLEMSEHRSWLYLEEMVNSLLNTAQQLKTLFEQAKQASSCREAAVTQARMQVDTERKEQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHVCGQSASVTVQADDVHVEESVIEKVAV
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.
Sequence:
MEGDNARRNLRDFLSMYNQFTETCFTRCVQNLNYRVLTPAEDSCTSNCISKLINVNHREISTYMEINPLNRRLNEMNSEEGLQPETPDLALEVEKVIGKDAIITLPSETESVAESSEAAHITPTALDGDVNQNSATMMNPDVTSVEADET
The following text describes a protein:
Function:
Tumor suppressor that is a key regulator of the G1/S transition of the cell cycle. The hypophosphorylated form binds transcription regulators of the E2F family, preventing transcription of E2F-responsive genes. Both physically blocks E2Fs transactivating domain and recruits chromatin-modifying enzymes that actively repress transcription. Cyclin and CDK-dependent phosphorylation of RB1 induces its dissociation from E2Fs, thereby activating transcription of E2F responsive genes and triggering entry into S phase. RB1 also promotes the G0-G1 transition upon phosphorylation and activation by CDK3/cyclin-C. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Inhibits the intrinsic kinase activity of TAF1. Mediates transcriptional repression by SMARCA4/BRG1 by recruiting a histone deacetylase (HDAC) complex to the c-FOS promoter. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm. Note=During keratinocyte differentiation, acetylation by KAT2B/PCAF is required for nuclear localization (By similarity). Localizes to the cytoplasm when hyperphosphorylated (By similarity).
Sequence:
MPPKAPRRTAAAEPPPPPPPPPEDDPAQDSDPEELPLIRLEFEKIEEPEFIALCQKLKVPDHVRERAWLTWEKVSSVDGILEGYIQKKKELWGICIFIAAVDLDEMPFTFTELQKSIETSVYKFFDLLKEIDTSTKVDNAVSRLLKKYNVLCALYSKLERTCGLIYLTQPSSGLSTEINSMLVLKVSWITFLLAKGEVVQMEDDLVISFQLMLCVLDYFIKLSPPALLREPYKTAATPINGSPRTPRRGQNRSARIAKQLESDTRTIEVLCKEHECNVDEVKNVYFKNFIPFISSLGIVSSNGLPELESLSKRYEEVYLKSKDLDARLFLDHDKTLQTDTIDSFETERTPRKSNPDEEANMVTPHTPVRTVMNTIQQLMVILNSASDQPSENLISYFSNCTVNPKENILKRVKDVGHIFKEKFASAVGQGCIDIGAQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMATYSRSMLQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKVEANLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDGEGPDHLESACSLSLPLQSNHTAADMYLSPIRSPKKRTSTTRVNSAANTETQAASAFHTQKPLKSTSLSLFYKKVYRLAYLRLNTLCARLLSDHPELEHIIWTLFQHTLENEYELMKDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAAQETFKRVLIREEEFDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFSSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGGNPPKPLKKLRFDIEGSDEADGSKHLPAESKFQQKLAEMTSTRTRMQKQKLNDSMEISNKEEK
The following text describes a protein:
Function:
High affinity receptor for triiodothyronine (T3).
Subcellular Localization:
Nucleus.
Sequence:
MPSSMSGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENREKRRKDEIQKSLVQKPEPTQEEWELIQVVSEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFSLDDTEVALLQAVLLMSSDRPGLTSVERIEKCQEGFLLAFEHYINYRKHNIAHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
The following text describes a protein:
Function:
Involved in pseudohyphal growth, cell wall metabolism and required for the separation of the mother and daughter cells.
Miscellaneous:
MISCELLANEOUS: Present with 907 molecules/cell in log phase SD medium.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=GPI-anchored cell wall protein (GPI-CWP).
Sequence:
MKFNFSTIFNILFFLFTLIEANSNGETVKLITSDGIVYSYAVYTKTLAPARVVVKTISYTTTRVYPITLANSVVSSTTEKITEVSTVSASEQVSATQTNSLVSTSTVSTISPTISSGSSTSSSSTYDIESSQSIESSGTSSATAEPSASSGFRLTSSSAFVSSTAPFSSQLSSSSSSETSSSSFSTSSSSAPLSLTSSSSSSSSFATIITLAPSSSKSGNSQLTLASSSSTSAVESSQTGSTIARTTSTLVPSSSVDTTSRATTSMPLESSSTQSISVSSSDGTCYVFYDDDDYYSTVYLTNPSQSVDAATTITSTNTIYATVTI
The following text describes a protein:
Function:
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1.
Subcellular Localization:
Nucleus.
Sequence:
MSINIVLEEIKGTPSSIIPLLSILHNDKQILSTITKTELNHLISRTLNLVRSSDVYNKWCGINLIRVIVEEYSILASEGNNLMNSLLQVLEAYQQQQHHHHHQTTIDLKILTSCIETINYMGDLIRGKPTLTREILTPKLNSIIGYYFQYLHFAPLLILNSLQTLLKFHPTTFRPFGNKLKTKLINLIDGGGGEEFINYPQDLQLSIYNTLAMLPIIEKIEPETKWYNDVINILGEINGLIQIYQEFLNFKDDQDLSNLIQKLPNRPTTTTTTTKLLTDLSIDFNKPQTILSISNHLNILMGVLKSYLTVETLFTVKLPLGLILTTCELICSINTKFLSFKGDIRDETIKKLIKFSLIENYKTTLGVLIELIELYKGSLIPHLTTIWSFLETLIPFQNQNKRIVNEEIIESESLYVEILQFMKQSLSLLGNVSENTQLLRFVDMALILVEPRINPTTTTTTTNNNNNNNNTKQTNVQQGKKQKKRKNTSSVALSDILSHEHLFMTNIPTITITTVRSFINQIITKIILPPTQHYKIMRYLIIESIHAKYYNLYHNVPIELKKLLINAVLYPGYDKISILPIISTILSDDPLLGVFNNPKFPPLPKYINLVNNIEEEEQKEEQEEDAIIEDEVEEPIKEELTTPLKKRKLDIESNEETDNNNIIPVEDQSKIFTATKVEKLTTTTTSSIENNPVVIEELTSSKEIVVESPVDEPTKVDNIIPTTTTTTTTTTSLTSNTANANDDNDNDDDDESSDFEMPEINLDQDSDDE
The following text describes a protein:
Function:
Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.
Subcellular Localization:
Nucleus.
Sequence:
WKISKPPLKGRDSLFQSLLLFRDVVIISEMLIFSDLDVDSTFKKAQVSSAGMQFSSHQSGHYPTPARRRHRTTFSQEQLEHLEAAFNKNQYPDIYCREDLARVTKLNEARIQVWFQNRRAKHRKQERAAQKPLPAVIPGCSGFMGGVCAVSSAGRQYQYSHTISHIPRFSSVIPSSYVPAPAVSQFSCASSHPHLSSGPTPPLQHEDWYSPLRAIGGPAPSLPPPMLSLASMPGLEPPPHWS
The following text describes a protein:
Function:
Component of the type III secretion system 2 (SPI-2 T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (Probable). SseC/SctE2 and SseD/SctB2 are inserted into the host membrane where they form a pore and allow the translocation of effector proteins into the cytosol of target cells (Probable); Required for the translocation of SPI-2 effector proteins. Required for systemic Salmonella infection of the mouse. Essential for SpvB-induced actin depolymerization in the host cell cytoplasm.
Subcellular Localization:
Secreted. Cell surface. Host membrane; Multi-pass membrane protein. Note=Secreted via the type III secretion system 2 (SPI-2 T3SS). After secretion, localizes mainly on the surface of the bacterial cell.
Sequence:
MEASNVALVLPAPSLLTPSSTPSPSGEGMGTESMLLLFDDIWMKLMELAKKLRDIMRSYNVEKQRLAWELQVNVLQTQMKTIDEAFRASMITAGGAMLSGVLTIGLGAVGGETGLIAGQAVGHTAGGVMGLGAGVAQRQSDQDKAIADLQQNGAQSYNKSLTEIMEKATEIMQQIIGVGSSLVTVLAEILRALTR
The following text describes a protein:
Function:
Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
Subcellular Localization:
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Sequence:
MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQNAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV
The following text describes a protein:
Function:
Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
Sequence:
MASIVSIETNAEHSTILGKRLGYCEACTANAAKYTCPRCDVKTCSMECLNIHKTELKCNGIRDRTQYIPLVKMTKMDLMNDYYFLEDCTKFVQDRKRDQRKRFTYHKKNLPIHMMRLQQAALDRGIVLKFMFQNFSKRQKNTSFLDFKTEKIFWRIEWCFPQTNENYVYIDKHICEDSKLCDIVDTYLQPSSKHIVPGIDKLANYQARGVAGVSLLLKAEGVQQSYDRVTLLNIHDTLRDSLRGKTIVEYPTIYVVLNDQLDQFNIIDSDDDLKDEICHINHTLHICACGVQPYNDGSLSNAKNERKNLSKRINFFSFEMLQNDSSDSDDTTLNENSISKRFKS
The following text describes a protein:
Function:
DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.
Sequence:
MDEETAYELERQKTIAENRALLDSLGLDPAGASSPFGSSPAPTSNKTKPKPKPAPKKRKAAAVIAVDEGPRRRSGRIAGLEADGDAFKAKVEEEEKEREILRVVSRKEREKVMDVGKMVEDTPEDEIKDMEKYLQSIAELSNPRTYPAGTVSAREAYADSDTVPSEVQRLKDAFKDMSLKGNTKVTNERVFSMCVHPEKTKTLVLVGDKYGQLGIWDALGPPMEKPENEDDTSGLLRAEGEDEYQEGRVWRVQAHAKNSISCMKVDPVNGSGLFSTAYDCSLRHLSFSTLQSTELFSFQDEDLLINHFDLLPSAQEAWMVDKNGGISHWDTRESKRESGRRRWVVQEEGRGAKLGGVSVNPLMPHLICTAGNDQHVRIWDTRHLFSISSNLVPSAAAIEEEEEGTSTLSGQSSSLPHDTHPTRESDYSTVTSYLASPRGKGLMRAKWQHGKSCSSAYWDPWGRRILTTSYDDHLRVFNIDPGSSLVDDRAVGSLLQPNGFKPTKVVRHNCQTGRWLTILRAQWSLNMEYMPHFTVGNMKRTLDVVSATGEKIVGLWTDDVTAVPTVTASHPNIVDRVVGGNTSGRIQLWSSGDHI
The following text describes a protein:
Function:
Palmitoyl acyltransferase.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Domain:
The DHHC domain is required for palmitoyltransferase activity.
Sequence:
MDSSEIEVVPLDSNSHQSPTESPTITDVFSASAYGDLHQLKHFVEHNGSSVSLPDDNGFYALQWAALNNSLHVAQYIIQHGGDVNSADNIQQTPLHWAAVKGSIDVADLLLQHGARIEAVDVNGFRAVHVASQYGQTAFVNHIIVDYAADYNALDIEGRSPLHWAAYNGFTETVRLLLFRDACQNRQDNTGCTPLHWAVIKENVEACTLLVHAGTKEELILKDNTGSTPLKLASDKGHRQLALFLSKAMRTRKNSFVDKIFCGKLGETSYAPMLFSLIVILMVLFITSIVSASNLPKITAMVGLWACFGLSCGVYALITFYRVSRKDPGYVKRTGEANSQHTANDPLIDINFKNPSWKGNWSQLCPTCKIIRPVRSKHCPTCKRCVEQFDHHCPWISNCVGKKNKRYFLVFVIMGALTSFVGGTTAVQRLWRGIPQVHHGESWIKHIVIEHPDAAVFLFFDLLIFIATMTLTISQSYMIARNITTNELWNAKRFSYLRGPDGRFYNPYNHGLRRNCTDFLVHGYTRDDEVVPSSIL
The following text describes a protein:
Function:
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays no strong substrate specificity with respect to the carboxylic acid moiety of Acyl-CoAs. Hydrolyzes medium length (C2 to C20) straight-chain, saturated and unsaturated acyl-CoAS but is inactive towards substrates with longer aliphatic chains. Moreover, it catalyzes the hydrolysis of CoA esters of bile acids, such as choloyl-CoA and chenodeoxycholoyl-CoA and competes with bile acid CoA:amino acid N-acyltransferase (BAAT). Is also able to hydrolyze CoA esters of dicarboxylic acids. It is involved in the metabolic regulation of peroxisome proliferation.
Subcellular Localization:
Peroxisome matrix.
Sequence:
MSSPQAPEDGQGSGDPPGDLRSVLVTSVLNLEPLDEDLFRGRNYWAPTTRRLFGGQIVGQALVAAAKSVSEDVHMHSLHCYFVREGDPKVPVLYQVERTRTGASFSVRSVKAVQHGKAIFICQVSFQQAQPSPMQHQFSMPTVPPPEELLDSETLIDQYLRDPNLQEKYRVGLNRIPAREVPIEIKPVNPPPLNQLQSMEPKQMFWVRARGYIGEGDIKMHCCVAAYISDYAFLGTAALPHRWQHKVRFMVSLDHSMWFHAPFRADHWMLYECESPWAGECGATWDKGTDLGVAGSPSTSCGALHRSFALLPPRLWHPCLQNDSERFEDRTPAQLLISITCWEYDLLYLIDPLQILCMIFGKSHLLPELQFPHLSKQGHIRTVVSKPGGPSDRHLGELFQNRLSDFIPKILTQQVLDEVQETIFKKLPK
The following text describes a protein:
Function:
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Sequence:
MKIFLSVLEVSADVHGSKLINALKNKKKDIYFYGLGGERMKEEGMEVMYDVTQYSTVGFIEPIPYIPKLLLVQEKVKKIIKETKPDLIIFIDAQGFNLPLAKYAKKLGIQTIYYFAPQYWLWGNQEKAREVLDTVSYVVATFPQEYNLYKKFGDNVVYFGHPLVDYLLPYENLEKENDLIGLFPGSRIQEIKNLVPLFLEISDRLKEEGYRFVMPIASEKFSEMIFRYIRGKNHIELVSGRESQKYLKLSSLSLVASGTVTLEAAILKTPVMVFYKISSITYNIAKRLVHYSFIALPNIILNQMIYPEFVQKIDIKEVMDSINRILKDEDYKINLENKLRELEFKLGEPGVLERISKFILEII
The following text describes a protein:
Function:
Regulatory protein of the TOL plasmid xyl operons. XylS activates the xylXYZLTEGFJQKIH operon required for the degradation of toluene, m-xylene and p-xylene.
Sequence:
MGSILSLRHYSHDQIVHSHDHAQLVLGLSGCLDFEVEGRGSRVLRQTFAVVPAQARHACSSPSGSRCLVLDLPCDGSLLLGLGEHAEAGRRLFERPQALSLTPAQGQLVNWLASGPINDPVIAHQGAGLLLASLASERQPPRQQPRLPLASLDAYLDRHAAHPLQVADLARLAGLSVARFHSLFLAETGQTPMDYARSRRLHQAHELLLESSLAVGEIAARVGYASQSAFTAALVREFGVTPRQLRRESRDKTG
The following text describes a protein:
Function:
Cell surface proteoglycan.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MFRAGSQNADLCWLILLGFSCLQEASGRAADAGGCHEVKTAYMMRQIGPVELVPDRPGTGESLRLCSHPGPTCCTGKMEDSYMTAVRTETQQKMRSYSFELKYLIAGHTKAYQETFDSLVSFTSDLTSTLFDSAYSTLASDSRPLVLQLFSDVKRHLSGDPHSSLDTAVRRFYDDLFPLVYRRVLNPGLGHTSRSFPSTNHDDCLRMTRQDLSPFGPHPWLLTSSLSRALRPGRTLSQLLRLAGEVVNATEKATLSRECGRALVRMQYCSHCKGLTLIRPCTGLCINIMRGCLLGVSELGAPWSSMVVLLQRLSGTLATSSNQNSLELALLAVRNHVNDAILHAQLHGPRITTLVEKVCGSQVPGPMISTEHSSHWHTTTRETSSFKRSQVTSPSSLQQSLQSRKSLPLKSSGGGKSRSLKKLSREFEGSIQRYQWFFSELPEMLCESEMEVEQHTCWSGQDVVESYAGHVAGSSLKAQKENPEMSVRNTDAVLKGAKKKLEQRTQELLVELGWASKGREREDRGGSMEKKEGGSGEDCDDEDGCETSGQESGDEISSGHSPETKDLAAPHHLHPVPPHLHSPPQVVVRDSAHLLTSGPLTSVILLLLLLCPWAPR
The following text describes a protein:
Function:
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Subcellular Localization:
Nucleus.
Sequence:
MALQERLDKFKKQQEKCQTTLSTIAATKAAAATQKSATHASANGRNAAPAVKFSNDTERLQHINSIRKAPVGAQMKRVIDLLLETRQAFTPEQINEACYVDMKANKDVFENLRKNPKVNYDGQRLSYKSKYGIKDKTELLQLVRKYPEGLAVIDLKDAYPTVMEDLQAMKAAGQIWLLSNFDSQEDIAYPNDPKVHIKVDDDLKHLFRSIELPRDMIDIEKDLQKNGMKPATNTAQRRSAAQIQGISSKPKPKKKKSEISKRTKLTNAHLPELFQNLNSS
The following text describes a protein:
Function:
Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.
Subcellular Localization:
Secreted.
Sequence:
MGGCFAWLRLPMAVLGLAASAAGLQAYPETQVCRLTDVSVEWVHGTMKRQGVTEYDIWGHSRGHVDVQVPRSVAEVLEGCEVMVEDVDALLQEQAARPGAAGRDGAAQVPLGYAGTVGDVFFDDFQDLETIYMWLDMLEQTYPGLVTVERVGQTYEGREMRAVHISAGNEQRNPDKKTVVITGGVHAREWIGVSTACFVVERLLSRYGRAPKETRYLDALDFLVIPVFNPDGYAYTWTHDRLWRKNRQPTYMPGCDGVDIDHSFDYHWTGQHAYPCSGDYSGQQPFEAVEARSWNDYVNKTKAELDIYAYLDLHSYSEEILYPYAYSCDALPRDLENLLELAHGLARAIRRKSGRNYDVLASCKDRGSDLSPGMGSGSALDYMYHHRARWAFQFKLRDTGSRGFLLPAAHIKPVGRELYAALMYFCDFILNPEL
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence:
MSLQDGQDYYALLDTNRGQVLIDLYEQETPVTVNNFVTLARNHFYDGLRFHRVIDGFMAQTGDPKSADDAQKDAWGSGGPGYQFPDEVRSKLTFDTGGQLAMANSGPNTNGSQFFVTFGPAAFLDGHYSLFGKVVTGDDVLAKLTRTAETSGGQETPIAGAVPDKLLSVRILTKNK