lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Associates with STAR2 to form a functional transmembrane ABC transporter required for detoxification of aluminum (Al) in roots. Can specifically transport UDP-glucose.
Subcellular Localization:
Membrane.
Sequence:
MRRLGLSLHHDTSPSFAALACNQRPPPNGTVHACSKSRPPQLEPGKVGKKPIKKTMRIARIPTSIPPHLRLPLDLSAVSPMGSASEHDVREHLLDVDGVGEEGAAAAAGPKIRVRGLTRRSEARGEEILRGVDLDVPRGVVVGVIGPSGSGKSTLLRALNRLWEPAPGAVLLDGVDICGIDVLALRRKVGMLFQLPAMFDGTVADNVRYGPQLQGKKLTDAEVQSLLSLADLDPALCSKPASELSVGQAQRVALARTLANDPEVLLLDEPTSALDPISTQNIEEAIVRLKKTRGLTTVMVSHSVKQIQRIADLVCLLVAGEVVEVLPPSELSEAKHPMARRFLELS
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MSYNQRETPRVYSVLARHGRQTLAALARASYLNGRQIKYGLVILLQQHLLFHSGNDGSVTYYEIDWQNSYALVRFGKVAKLVEDRFGKKAANVISNLLTLGHTRIADLKEAYFPPPVESDDESDDGMVNGAGSKRKRANGTQVNGHGTKTNGVVNGLPAELEDSKPDPELLKNGATNGAPKTEKMNGSAHDSAHDDGTELEQDEIASVDEFYDIIQILIERGWVRTVTDSQYLSPGDMHDMLQAAAIEQELNGNAMTGIKDKEKVHRATLQMKRQMRDEWLVAPKFSRKRQADDTHHVHPNKRVKTNGLFHSTAGTKSAEDDLVIRVNPEKVAVAMRTQQLVQLVENRLGPTTAHIYEHMLRMLEANTPRCYEEFPEPPMVGEAVGEAPIDPRLLVTARDIAKKIDRDLDICEGLDPNAVVGVARKGHVRTSNALSQPIDPEKLSIDERTQLVDKHIRLLAEDPLHFATWHSRAGFSQWQIEFEEIAKQLIQAEVENTISARKGALGVKLIRALRKKGKLDERATCNAMMMSANDIRGIVNDLTVQGFVQTQEIPKVERREAKHSLHLVWYDRQRAREKLLHDTYKGMVRILQRIAFEREKVQPLLSKAERSDVVGNEAKWLSKAELDALQKWKEVQEKLLLQLFREDDLVATLQTGLGFPGLAHIGQAQKASLLHKATYMKSITRMTDCAAYRSTNTDLQNMAKDTPIRRSTRSKKPSEKFLANIAQAHVEKRRSRRLALLEKGEGMIDTPIKRRPLIQKRLSEFVVGDTDSAASSSSEDESHDGDSDFEAAPSPSPEPEERIDLTRDHFEYMAADELDRRESYDSRLEEGNEEYERDGFVVGDEESEYDGKEGTVWDSESDEVTIVGEGEEGDSVMSDSDSDSDSISIPHASPDSTPTSPGLFVSSASSTSSVSLSALFHPLNPSISPADVAEEINDAVSRFSRRCNRHSAPLRLELSAQVWADDEVSEAVERAVVLHLGQYAEVHGGSVIVTIGLPGMWVMDSYLR
The following text describes a protein:
Function:
DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MENKNFENLNLNEDVLKAIQYMGFETPSAIQEKSIPVVLEGADVIAQAQTGTGKTLAFGAPVISALCDKEKKKGVKALVLTPTRELALQIKDELKRLSKYSKTKVLPVYGGESIERQIKDIKSGVDIVVGTPGRILDHINRRTLKLGGIDFLILDEADEMLNMGFIEDIETIMESTSEEKQTMLFSATMPAPIKKLALNYMKKDVEHIAILKKSLTVDKIAQHYFAVKNKDKLEAICRIIDSEEPESAIIFCRTKRGVDELVEAMQSKGYNVEGMHGDMSQNQRINTLKKFKKATLNFLVATDVAARGIDVENISHVINYDIPQDAESYVHRIGRTGRADKEGTAYSLVTPREVSSIRQIERIIKSKITKKELPTLEDILEKKYDNLLNDITSKIEENKYEKFMPMVKTLEQNFDLSQVSAALMEMLFSKEMSFDYTNDKLEAEVPVRLFLSVGRKDSINVKSLLTFIQDEASVKNHEIGDIDILDKFTFMDVSSSTAEKIINKCSGKKLNRRKVNIEIAKSKK
The following text describes a protein:
Function:
Transcription factor that acts as a regulator of embryonic stem cell differentiation during the preimplantation stages of embryonic development; [Isoform 1]: Transcription factor that acts as a positive regulator of embryonic stem cell differentiation; [Isoform 2]: Transcription factor that promotes embryonic stem cell pluripotency; [Isoform 3]: Transcription factor that promotes embryonic stem cell pluripotency. Also involved in extraembryonic tissues development by promoting the expression of placental prolactin family genes.
Subcellular Localization:
Nucleus.
Sequence:
MEASPRSLTSCTLGPLDQKFSWEQLSELEAYFKVEPYPDLQDRKIMATRLKLKEEQVEAWFIQRSLEEEMRPPLARLQQSALDGTSSPSHKALCCRPPSWKYRLIPINPPESSTSCLKDSKTVLISKTELTDEQFQKLRKHFETDRCPNEETLQAFAEELKLRKDLIRSWFITQRHRMRGYRRLFMRYYRDWKTSREYSTTRSFDRQKNSKECSQNDPGLPEALEALKRLKLSSGYQSRDGMSQDF
The following text describes a protein:
Function:
Acts as a catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MRRSRFVAQVFSDVTFADASTISAPIFTMSTRAPYRGARGRGRGRGGRSFSDRPYNDDAGRDQFVTGDSHFQSVHDANFRFRHGEPYRQHQPPLDQRQQPPFNQNYEFRPPPPSRGQWQQFRQPNQFPSNQNYAACPPPPFYQNQMSRPPPQQSFRQRPRSKPSDYREWEYAKTPPSPGSEKFVVLSYNILADYLANDHWRSLYFHIPRNMLSWGWRKSKLVFELSLWSADIMCLQEVDKFQDLEEEMKHRGYSAIWKMRTGNAVDGCAIFWRSNRFKLVHEESIQFNQLGLRDNVAQICVLETLLTSHTKENETPPPESSAGSHRVVICNIHVLFNPKRGDFKLGQVRTLLDKAHAVSKLWDDAPIVLCGDFNCTPKSPLYNFISDRKLDLSGLARDKVSGQVSAEFRPPRPENYTTRYQSANKSPQGQVQPPNLITNAHMENNSNIDVGTAPSEKTSELPCGDTILAGHEATSSSDQVLPCENMASDCQFGIENRKPDDSGNLSTAEDLSSLTISDTEPQHASSAREDLNTDRSVSSGLSETEQTPEEICSSDQDISSSLSTKVDTFVAEMKLDGLKLDEPVVFAQDEESLGEDGETFLAKLHDNNENLSQKGELVSEVPLKWSSEALNSDKITYSPSSWTPMEIATATGDPERTTVEHALELKSTYSEVEGQANTRDENGEPVVTSYHRCFMGTVDYIWRSEGLQTVRVLAPIPKQAMQWTPGFPTPKWGSDHIALVSELAFCSSKTLPKS
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
Sequence:
MAEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFTIPDFKVGTLDSLVSLSDELGKLDTFAESLIKKMAQCIVEVMEDAKGKVQENLLANGGLKEKMKCLKIDLTTFVTRFEWDMAKYPAKQPLVAVVDTLAKQLAQIETDLKTRTAAYNTLKGNLENLEKKSMGNLFTRTLADIVSKEDFVLDSEYLITLLVIVPKTSYAQWQKTYESLSDMVVPRSTKLIAEDNEGGLFTVTMFRKVIDDFKSKAKENKFIVREFFYDENEIKNEREELAKLVSDKKQQYQTSRVALKKGSAALPDHMVKVTPLGNTDRPATGQTERERESEGEGEGPLFRWLKVNFSEAFIAWIHIKGLRVFVESVLRYGLPVNFQAVLLQPHKKSTKRLREVLNAVFKHLDEVAAASMMDAAMDIPGLQLSNQDYFPYVYFHIDLGLLD
The following text describes a protein:
Function:
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSLASFPKPHYGSLPSPSSSNSTTYFVTCATTSTRSSFATHQPWEEVFTLYSFTHPYSIEEATMRVRRNLDHFRMNYSMMVLFVLFLSLLWHPFSIIM
The following text describes a protein:
Function:
Transcription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs). Binds to the GCC box (NF-responsive box) of ENOD11 promoter. May act as transcriptional repressor of NF-responsive box-containing target gene promoters in root hairs.
Subcellular Localization:
Nucleus.
Sequence:
MDYQNQKSNENKHGEKLMMKNRSKFVGVRQRASGKWAAEIKDTSKNIRMWLGTYKTAEEAARAYDEAAFLLRGTNTRTNFSTTHSIPTNSPISLKLKNLLHRKSISNLSQSKNQCTLMSSSLQGAPIDNSIMVMENENKSSCSSEESKSLFWVQNQLVSEYNPYGVDMNMMNCSIGITPNTLQIDYSWPLPQQRINELPTLNDSVNVYGMNECYVEGTYESKYEYDVNYPLSHLFCFT
The following text describes a protein:
Function:
Involved in DNA damage-induced apoptosis: following DNA damage, accumulates in the nucleus and forms a complex with p300/EP300, enhancing p300/EP300-mediated p53/TP53 acetylation leading to increase p53/TP53 transcriptional activity. When nuclear, may also act as a component of some chromatin regulator complex that regulates histone 3 'Lys-4' dimethylation (H3K4me2); Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC).
Subcellular Localization:
Cytoplasm, cytosol. Nucleus. Secreted, extracellular exosome.
Sequence:
MLEVTVKTLDSVSRPFTVDEETTVREFKETIAESVNIPPDKQRLIFQGRVLKDHTKLKEYNVHGNVIHLVERAPPPRQPPTSSSSSSGASTSTSSSSSQSAGTTQGGGDRNGNNFVIGAFTLPADVVDPNQIQNVVQSVLSGMGDLGRNARVTSRASPDGSSVDVHINLGQIAMPQLQSESQLRIDQAQRMVREAHDCLNRLENPPGRQRSNSLPSSLGEQPPQGEGAGVTSRDAESIPSSTTNTTSTEEPMETETATPRETGGQTQETGGSASDTAPGTAAAPGTAAAPGASGPSSTSQPGATGANTQTSTPTTSGTPTSSAAGTARPGPQHPAPAVLADVFDEIQALNERLRPHMERYHQILRNEVDYTGQFEEYRENQRLVNIISQILHNLSHAYHSLSDIMLDLSRTPPRYLRAPPAPQIQMMGPVQTASQIRIPILQQFQNQATFTTSAPGMGAAASRTSTGTSAVPQTSSATSQTPPAPQAQVSTATTQTAHAPDTTAAPTSSQDASAANNDLASAHTQTDGTPLASAQTQTQTTEMRTTTTTTQTNQGQPGATFRQVIGGGGTPSDPLVMLEMGPQGFYINRITATIHPPGQGPQQASTAGVSAGTSTTGSTASSTAQGAPPASSAPGPSVTVTRHFTTTTNPAGARFSTGAIPMAPPQLMQQIMQQVSQHAASATATAAAAAATAAATAAANMAGPGQRQGQQPPQQQPAGNGRTSTAAPGRPGTQPPGNMGRPLPRFTTGQPGRGPMAVPGTVALNPTDPFLPCSSRHFLVVRQNQNQQPRAPPPQQPQPQAGVVSTGDGQLGDMIQGVLQGLMQQQNPYLHPQGAPGTGPRGPPTQPLNPQAIVNMFDAILQPPASSAGGQAPPPATPQGAQSFSTTFQDIVQDGIREAGSQSTMSSSSTNTTTTTTAGSPTTEPSPGTQPANQSDQPPAPPPRAGVSDETFHSLIGGIGGFMQQAAVGQPSAETIADFLTRISPEYNIQEEEGFLAELFQLLTSSFTFLDLMRLFFGQSAPLANVRPQLEQFVTSQLQDQPPTQANIQAAVGRILDSMQCYITDAINDAQVQGHDNIDLVRTHTEFCRHHMYRVMNIIANSTDDDAGFAQRLFEACRVAVQEWLRLSTSCITDGLRGVERIINSRMRVLAGEVNPAILTWMQTMSTGHLRNLMQTVSVPESQIQHYYVRREPQPAQVEQAAPDSTPAAPDTVAEEVTPTPDNRAQEVTRAEEVTSCQGQKRDRANAEESRPQENTGRSEKAGSLNGVPEPEAMDDEEEPAGAPGLPWQSVVPADWVPVIQRDIETQRSLQPQPPFSDAYSTGIPAKRRKTSHAGREIGSMSSVVPEALKQAVLSSGVQPTTSMEEFTEEAESSATLHAAYEQQVRSSVRRRLRNDPNYTPERFPSTHKYFEEDNQ
The following text describes a protein:
Function:
Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSSPALLRHPEDSMPATAVAEAGPAPTAPPKTPPSFGTLALRWYRLNQGRLRATAIGIASLIAFLLVWHLLTTYRVVFFVRFTNVPSPLAVYASFTKAIHDPKFLMHIVLSCRRIFIGFSLAAIVGVPLGLIMGRFKLVHEIIFPVAEVLRPIPAIAWVPMAIMLWPTNEQSIVFITFLGSFFPILVNTLHGMSLVDPVLVRAAQCLGARERSIFREVYFPASLPHIFTGLTVGMGVAWVSLIAAEMISGQYGIGYFTWEAYSLVQYADIALGMIAIGVLGLGSSLLIRGAGQLVMPWRST
The following text describes a protein:
Function:
Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MESRTNSALFKRAEQLRRWEESETNKEPASARVVSRRIQFSDGCVFLSACAAGDKEEVLKLIRQGADIDTPNVDGLTALHQACIDDNLDMVEFLVEHGADINRGDHEGWTPLHATASCGFLSIARYLIENKSDVAAVNNDGELPIDIAETEAMEELLERETQLRGIDCDAARSQEERQMLADTSRWLEGDPASARLLQPHPRTGATPLHVASAKGYIRVMSMLVQGGGELNIQDIDGWTPLHAAAHWGQREACQLLCENMADMEVRNYVGQTCFDVADPDIIRLLEECKKRQAIILRERPEVYNNRGNARNQSPPKRRSSVTRTPQTEKAAIQASSKITDKVPGAVIMVDEEKENSSGELSSPVAPLAVQESFDERAKPATTPATTTTSVPTSTKDNSPRVTSSSGPPSRPPPPPATDVDNLPSSPSQQSGQMIETEEDVPSWRRPGSFRSRQAANAANGSATLNHTPVKSEREGLNRSISQPLTPVAAVTSSSSATPQSSSTTSSNLASTASSISSSTSALSTDTEVTLRRAHSFESDERFYSRLLELRRRIKANSLPLLAASSLTPIVSGGSNSVGEDVNGGGPTSTNTIHSTNNRSRVEQTLQPIDDLEPVVLRFVISIEYTNFLKFVVVFVPFCSRLGTECPVEQTTTATLVLSQPNVPSSANQPIRSPSANTVVTTTATSSLTNVKLSPGTIIKNFFKSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLEEVKTAEQLAKKKQAETTSIPASVTPDATESADSKSELERRPSWRLCINDNNKNKFSLEDSRSKNNGGGGVNASSTITSTTADTVITIPLRRSKAQEEEMKETTKENAAAATPATIQRRRRPKRRSTGVVQIDMEDFDPSGKDNTSSSQTGDSEPHSDDSEG
The following text describes a protein:
Function:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
GSNAQKKKLQHNKHKTQGTNVVHRSPRALFCLRLNNPIRRAAISIVEWKPFDILILMTIFANCVALGVYIPFPEDDSNVANHNLEQVEYIFLIIFTVETFLKILAYGLVMHPSAYIRNGWNLLDFVIVVVGLFSVILEQFSHKPGEAHHMSGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKAMVPLLHIALLVLFVIIIYAIIGLELFIGRMHKTCFIIGSDLEAEEDPSPCAFSGHGRECTVNNSECRGKWEGPNGGITNFDNFFFAMLTVFQCITMEGWTDVLYWMQDAMGHELPWLYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQMEEDLQGYLDWIMQAEDIEPDDEGDEADEKHTPSLPASETTSVNTENVGDEEHHEKNCCDVCLGKLAKTKFGRRMRRINRLLRKRCRLAVKSVSFYWMVLILVFLNTLTIASEHYNQPDWLTQIQAYANKVLLSLFTLEMLLKMYSLGLQAYFVSFFNRFDCFVVCGGILETVLVEFEIMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDTFPQALLTVFQILTGEDWNTVMYDGIMAYGGPYFPGMLVCVYFIILFICGNYILLNVFLAIAVDNLLECEEEEEEEEAEEGSEEHKQEFIQICSSNRLLIYDGLNSHLQTHHQDPTPGRQLYLATSEEEEEEGDQQSLAESHLDKVEDTPTEKVMPIPDGSSFFCLSKTNPLRVGCHKLIHHHIFTNLILVFIILSSISLAAEDPIRAHSFRNNILGYFDYAFTSIFTVEILLKMTAFGGFLHQGSFCRNWFNLLDLLVVSVSLISFGIHSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYSCTDEAKHTPNECKGTFIVYKDGDVAHPMVRDRLWLNSDFNFDNVLSGMMALFTVSTFEGWPALLYKAIDANAENEGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIITFRAQGEQEYKNCELDKNQRQCVEYALKAQPLRRYIPKNKYQYKFWYMVNSTGFEYIMFVLILLNTIALAVQHYEQSQPFNYVMDLLNMVFTGLFTVEMVLKIIAFKPKHYFCDAWNTFDALIVVGSVVDIAVTEVNSSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQILAYITFGKVAMQDGTPINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGKRCDPESDYEPGEEFTCGSNFAIVYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPAAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNADGTVTFNATLFALVRTSLKIKTEGDLDVANKELRAVIKKIWKRTKPKILDEVIPPPEEEEVTVGKFYATFLIQDYFRKFRKRKEKGMLGADGSPSNSTALQAGLKSLQDLGPEIRRAMSCDLEEEEEEEENGETVCEEETVTYKGIFLYGGTINYVFIMSMKTKLFSCPSSTEALYGSAPDQSAAPASPEQEGKTLMNGLVGSRHPSSTSLSHVANGPTHYEDNVGSHDEPTELPSMPTRRRLSRRSSDGSCIPPTVKEETNHNEDYGEDTSVEQGYYSREEDSESLASRERPTSNYSQLSVCLGQGQPSLHNPRPHRHHWDNGYGGSLPLPSRRMNNGLVNGMLDSRQPKRRRLLPPTPTGRKPTFNIQCLQRQGSCDDIPIPGTYHQNAPPCRARAQQVFSLGYGSYDSWQSGGRNSTASSQSWATPPKRSRLLYAPLILVEGDELPGHSWEKNSSLPPMSRARWYMNEPEMPYRTYSHLHVPGPLKHSYDKRGSADSLVEAVLISEGLGLYARDPKFVAFTKREIADACHMTIDEMESAATDLLSRKYVGSENGSRSSSGGGHALYSSDGEHSGVGSVGPVYSDEEPFRSPREEEDLADEMACVTSY
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTQSVEDNSVLSKLNVSNGDNMMAPNSNGNLKGKNCLESELESILLKQQQQQHQHNRDLVGERERDLNMSRSGSAPPTVEGSLNAVGSLFKNSNLAQSSGNNSNNNGNSTSSEILTEEQIRSHPAYLAYYYSNVNLNPRLPPPLLSREDWRIAQRIEQGGNSSLFAMQPGFPTQRAENEMINLRKTAARNLSRGTLEPSSGIGVRKKSFADIVQEGLDQPARSSADLSHSPSTETTEALHTGKAPPGFSGVEKVQNPKPCHPNSFTSAIGSSQRSRTPEPHPFRKSPSPQLSVGHGDGIDIAFLSQLHYNDNMQQPWFQIRVSNGYMQGDHQQFMEYCGAEKLATASEFADLVKDKYVLRDHNSTFYVDGRANFLRTLSPEFVSQKSNVQHQVNNYQNVDSTGYIPGGYKYNQKLNLALNGNLGVQLNGVSANGRHLRSDSKEATQYLQKTSVDNSSKGRNLVGASHGNTDLKVLGTMYADTSLPQQKQQYPSSFLHNCYSLRDQYHSTHALGSGIIPCQENKLANSWHSDNVAEGRVVPSLLDDLKNNPRSLDLLDVLNHVVEFSKDQYGSRFIQKKLETATVEEKMKILPEILPHAHSLMTDVFGNYVIQKFLEHGTESQRKELARQLIGHVLPLSLQMYGCRVIQKALEVFDVELQTKMVTELDGYVMKCVRDQNGNHVIQKCIEHVPQDRIHFIVASFFGQVVSLSTHPYGCRVIQRVLEHCNDSKTQKIIMDEIMQAVGTLVLDQYGNYVIQHVLQHGKPHERSIIIGKLTGQIVKMSQHKYASNVVEKCLIFATPEERQFLVNEMLGSTQENEPLQAMMKDPFGNYVVQKVFETCDDQSRELILSRIRIHLTALKKYTYGKHIVSRVEKLIATGEKHVALSSNSSRGNPVFKN
The following text describes a protein:
Function:
Involved in vision.
Subcellular Localization:
Cell projection, cilium, photoreceptor outer segment. Membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum. Golgi apparatus. Note=Localizes to photoreceptor disk membranes in the photoreceptor outer segment.
Sequence:
MCTTLFLLSTLAMLWRRRFANRVQPEPNGVDGAVSGSSLETDLQSSGREKEPLK
The following text describes a protein:
Function:
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
Subcellular Localization:
Nucleus.
Sequence:
MASSTSNSAAARMQTHLQTEPQNRSQNQLQGSVTITQSQTHTSAPVLRLRGESTGESESSTNGERGLGRGRRIQWAEDVVDNEGLGRKKSKVCCIYHAPRPIDESSDESSSDSDDSSSDDDGGAKPSGGNGDKHDHGDECAHGHAHGKGKGKGKERKRSPNAYERQPNYKGKDKGKGGG
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that acts as a regulator of antiviral immune response and inflammation by mediating ubiquitination of substrates. Acts as a regulator of innate immune defense against viruses by mediating 'Lys-63'-linked ubiquitination of MAVS, promoting MAVS polymerization and formation of three-stranded helical filaments on mitochondria. Acts as a negative regulator of the NLRP3 inflammasome by catalyzing 'Lys-48'-linked ubiquitination of NLRP3, leading to its degradation. Regulator of Src-induced anchorage independent cell growth.
Subcellular Localization:
Cytoplasm. Mitochondrion. Note=Predominantly expressed in the cytoplasm but a fraction is associated with the mitochondria.
Sequence:
MAGQPLACQLQEEVTCPICMEILQDPVTIDCGHNFCLQCISQVGKTSEKIQCPLCKLSVNKNTFRPNKLLASLAEKIQSMDPADIQAEKEDSRCQRHKEKLHYFCEQDGAFLCVVCRDSKDHKSHNVTLIDEAAQNYKVQIESQAQDLGQKDKKIIEEKKQGEGAIWAFRAQVDLEKLKIHEEFKLLRQRLDEEESFLLSRLDWLEQQGAKQLRQYVTVTEKQLNSLRKLTKSLKIRLQSSSMELLKDIKDALSRGKEFQFLNPNPVPEDLEKKCSEAKARHESIIKTLTELKDDMNAEGKRDKSAFMNSLNKEEKESWSLLQKNNSVLPTSVPVTLDKSSADPDLTFSQDLKKVTLYIVAGKASNRQAKPRPFYPFHCVRGSPGLSSGRQVWEAEIRGPSGGACIVGVVTELARGAQSQTVSAQSYIWALRISPSGCQPFTNCKAQEYLQVCLKKVGVYVNHDCGEVVFYDAITSKHIYTFQTSFDGKVFPLFGLQVACSHITLSP
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MKAPSNGYLPNSGEGERKLMNSELWHACAGPLVSLPPVGSLVVYFPQGHSEQVAASMQKETDGIPSYPNLPSKLICMLHNVTLHADTETDEVYAQMTLQPVNKYDQEALLLSEMGLKQNRQPAEFFCKTLTASDTSTHGGFSVPRRAAEKIFPPLDYAMQPPAQELMARDLHDQTWTFRHIYRGQPKRHLLTTGWSVFISSKRLCAGDSVLFIRASPSEFVIPLAKYNKAMYAQVSLGMRFRMMFETEESGVRRYMGTITGVSDLDPIRWKSSQWRNLQAMSLIESSVATPDQCLLAFWFMFLVVGWDESTAGERPSRVSIWDIEPVVTPFYICPPPFFRPKFPKQPSFPGDESDIENVLKRGMPWINDELGLKDAQNSIFPGLSLVQWMSMQQNNHVPVAQSGLPSVLHSNIGSDDHSKLLNFQSPALATPGLQFNKPNQLNQPFVNRCVSPNQIPNQTFPQAAVYGQLQQQQVLSASTQSQQNVPVSRNSFPSTSLAQDFQFQQQMEQQSNLLQKSQQQQTIPQQAPLQLLQQSLMQRSQPRMPQQQQNRQPQELQFAHQQLSSNIVTTVTHLQSTHHAFNQLQNHHKSPITIKALSGGTEGDAPSCSTSPSTNNFQVSPPNFLTRNQGQAILVDESVVDPSQEQNKSECRIKHELVFSKGSELSKYKGNNTENLEAASSTTSYGLDSSGFNFSLPALCVDGDVQSHSRNILPSAANNIDGLNPDALLSRDYDSGKDIQNLFSPFGNAPRDIETELSDAGINSQQFGVPNMSYKPRCANDLAVNDNGILNNNAWTNQTQRMRTYTKVQKRGSVGRTIDVTRYIGYDELRHDLARMFGIEGQLEDPQRTEWKLVYVDHENDILLVGDDPWEEFVSCVQSIKILSCAEVQQMSLNGDLGNVPVPNQASSGTDSGNAWKGHYDDNSAASFN
The following text describes a protein:
Function:
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.
Subcellular Localization:
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Sequence:
MSFLLNLIPAISHTNHDEMHEPNQTHLHRHADTSPTNQHNTSHKMTTTEPIHVTTGSGESRDHTEPRHVTPTSPNALDGRRITIAYATETGNAQDFATLLGNACTRLRFESHVVQMNDLSPETLAQDVSVLVIVCSTTGQGEIPLNGKKLWKFLLRKKLPPNLLSHVTFTTFGLGDSSYPRFNWAIRKIHKRLSQLGASEVGSRGECDDMSPDSIETMYNEWQARFCESLLKAFPLPEGVEVIPGEKLLPAKFPVKVLTNKPKRDTSDADHVACTRKDVLQGTVVGNERVTAKGHFQDVRFFQIDANTEDNDMADLSRDFSKLNSDSRDLHDVSRAVSAGSSIDFSTGDTVSLFPQNSVADVDLLLRDQGWEDIADYKLDAPSLPPIEGGYVTPLTLRSLITHHLDIMGIPRQSFFTYVFHFATSERQKERLQEFSQPGEGLEDLFDYANRPRRSILEVVTEFDSLKIPLKYVLDVFPLMRPRLFSISQKAHTMPIQLCVAIVKYQTIIKRIREGVLTRWLGGLAIGQKIVFTKHSTPIPDLDNYDVIMVAPGTGVAPMRSLILSRESEKETVLFFGNRFREKDFLFQADLEKAVGDKKLNLFTSFSRDENSGGYVQQEMYRQKELVARVLCSKQGVLYVCGSSGKMPREVRITVVTCIQEVNGWTEEQAEEWVKGMEKSGRYLQETW
The following text describes a protein:
Function:
May function as regulatory subunit of ATP-sensitive potassium channels (KATP) and form KATP channels with a member of the ATP-sensitive inward rectifier potassium channel family (By similarity). May also have channel activity by itself (in vitro). May protect the heart during hypoxia. May protect against heart failure under conditions of tachycardic stress.
Miscellaneous:
MISCELLANEOUS: Drosophila is predominantly active around dawn and dusk, and has large sleep periods during the day and during night. Knockdown of Sur reduces sleep duration during the first half of the night, but has little effect on sleep during the day.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKQLFNIIHCDHLNGHVRSIYDNLNTDICGIDRVRRVFTFFSIFLLLFGLMFVCSRYKKCHKTLLTFHNGRAAISLLLLALNSFDLARIFLPHQNVRNLNRLFQSSPRDLNYLVVIGSGELWNALFSTLLTLMLMLYHRMVERKKATVFLYASTAVEALTFALLSNELFELVRYEDFLELQTCLVAMSAMCMVSLAMLDGLTVYKECYHDDYLDDYGKIGYKHSMATFYSKSCFWWLTPLLWLGYKEPLELEDLGQMKLEDSARSHYDHFLYIYTEKKKKSNSSPSLWYCYIKNSWQMFALGGILKLAGDLFALIGPLAIQKIVEYIEQLYAQASEPPAKSPGNEVANVLLSTSRILGTEFDEVFGTNIDKGLIYRKSLLLNADGGCDSSDSAGQVQSTSSTSDEKQKNDDSMATPEHVDNPSEPNISHDIGSITNHMTEDTRNIMEFFLIIHYAWAIPFKIAVVIYLLYMNLGISAVIGSIACIVIMTPLQFFIGNAMSKNAEVIAGYTDERLKRIHDTLVGIKVIKLNAWDEVFLKKIQEARRKELKYLNKDATFWTLMAVLTHIATVLITFVTLGVYVWLHRDQEFDLNASRLFSSLALFQQLTVPLLIFPITVPIIIAARVSTRRLERFLKSSEIQKQFEGIRNMARILSKSDASLDMYETQEKSNMTMRTAQAENRLNEKRLAQKSQTPELATNSTPLLQNAEESAEDISPSTVQELGHNKLVQQRRELLRNTPYVAIRPPKMRGSVMERPVEFSVIRARNTDSWRRDSLLLKMPDDIAVSINDGLFTWQPQSQMPVVQLHVPGIIVPKGKLTIVVGKNGSGKTSLLSALLMEMPLLAGNMFWHKTCTISYVSQQPWLLNDTIRENILFGESFRPKRYDFVLEACALKPDIELMPRGDLSIIGERGINISGGQRQRIAIARAIYSSANVVIMDDPLASLDNEVGEHIFQHCIREMLQKSNRTFILVTQQLHRIKEAEYLIAIKDGRVEACGSYADIELMQPRITAEWNAIIAMAKAKNDNPSQNPGEKTAGERWKLLKNVSKLGLQRSISVTMDANVACHADAIDGSGCISVANMQSNVVEEDDQVSVSYPIGNASCGGFNLQRKRSSIYGSRHLMYDVPLPIDECQGDDVIMRPRRRHTLGRRGSRNTNSSHRLSGLSTLTATSESSSISGDVLSRSVLATSCSSYAESSVDGGDLATAAPEPRVQSWQPPQHVTHHQPLSRNASSPPAMEVANPDVKKSEEARRSNTSSESPLDDHVRGSFQQFLRRMSMRRSNKPKNHHHPLSATNSILSISEESPPVVHFPASILATDGNKNETQSEEKPKKCVNIDSKETTINCDDNCYSASDKELRANVTSSPADQEQHNERHVLAEVAGESGRESMPLARLAIDTERKYGKISDDIYLMYIRAAGLPIITIFFITALIWQCLRVYTDIWLQQWSNVHGRVASKGHVVLHPSEQDHEVTYYFRMYAAISCVCIIMALVSTPAGQYAGCNARRNLHDKLLQTILHKTLHFFQVTPLGRIVNRFSNDMAVIDKKIAATGQRLLQFTLLCLSAILINVTITPWILVLTLPICGAYYLIQKFYRCSARELQRIENATNSPVISHLSETIQGVTTIRAFNQQTRFTEILFKRLEANTIAYALLNTSHRWLGVSLDYLGGCIVFVATVTALTAASVSCRRHYEATTSPSASASPSPFETYAVTKSPSELRPSPSLVGLAINYTLLVPIYLNWVVKLLADMEMYAGSVERIAHYAQGQDADADADADADADVDADLDHEPSSNEDVSAEVDRSSQSDAGDKVYPGATTAAGDVDEDGDQQRIGGARGGGGDCGYRQGHENGAEANADKLNAGNVTGDGNHLNFHHPPATAGDKVEQATTKTSVIKDKQLPPQQDDKDKKVVLPNEPARKLERYQSVPISWPQRGDIHFDNVSLRYEGQKQNVISNLTLKIPAGQRIGICGRTGSGKSSLGLSLFGVLQTTRGHIYIDDVDIQRIRPDELRTRLSIIPQDVHLFNATIRENLDPHGYFQDLQLWNCLELAQLKEFVNGHLPLGLDTVICDGGLNLSAGHRQLLCLARAILRGSVCLVLDEATSVLDSSTESALLKAADLAFRGRTIITIAHRLTTILDYDRLIVLDQGRIVEDGNPRELQQLEGSVFRGLLEKGASKW
The following text describes a protein:
Function:
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNAWNTIYDQFNPIAFSLGSIEVHWYGLAYACAIVTAFYMALRMIQKDPKRFPIERKEFESYFLWAELGIVLGARIGYILIYEPNSGYYLTHFWQIFNPFDSHGNFVGIRGMSYHGGLVGFLIASYLYSRKDLKKLLIYLDLIAISLPLGYVFGRIGNFLNQELVGRIVPKDSHLGQIIGIMVDNELRYPSQLIEAFLEGVIVFLMVMWAKKHTKTHGLLIVVYGLGYSLMRFIAEFYREPDSQMGVYFLNLSMGQILSLFMVIVSLGILLYATKNSKKIKENQ
The following text describes a protein:
Function:
May be a cell surface adhesion protein.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MKHQFIVLALLFLINTAPTSAQPAASPTAPMVLPPPPVSLAPVSPAPDSPPPPAPPQAHLLKILQKAGGFTVLIKLLRGTHVSDQVDSELSDLNDGITFFAPDDAAFSALKAGTLNTLSNEQQVQLLQFHMVPTYLTMSQFQTVSNPLMTRAGGVGGKEFPLNVTTKGDKVSVFTGVDGASGEDSAQGPAPPTKKPAELSVSGSSEVGKVKTGDVVRLVVGVGVAGVVASLGL
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that regulates cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA. Also involved in protein trafficking and localization.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Nucleus inner membrane; Single-pass type I membrane protein.
Sequence:
MLLSIGMLMLSATQIYTILTVQLFAFFNLLPVEADILAYNFENATQTFDDLPARFGYRLPTEGLKGFLINSKPENACEPIAPPPLKDNSSSAFIVLIRRLDCNFDIKVLNAQKAGYKAAIVHNVDSDDLISMGSNDIDVLKKIDIPSVFIGEASANSLKDEFTYEKGGHIVLVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPIHKFKKGDEYDICAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSETDSSQEENEVSEHTPLLRPVASVSTQSFGALSESHSHQNMTESSDYEEDDDDNEDLDSSDAENEVNEESVVVQLQPGDRRDYDGANTV