lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MLKSSNKRKSKEEKKLQEGKYLGVRRRPWGRYAAEIRNPFTKERHWLGTFDTAEEAAFAYDVAARSISGSLATTNFFYTENTSLERHPQQSLEPHMTWGSSSLCLLQDQPFENNHFVADPISSSFSQKQESSTNLTNTFSHCYNDGDHVGQSKEISLPNDMSNSLFGHQDKVGEHDNADHMKFGSVLSDEPLCFEYDYIGNYLQSFLKDVNDDAPQFLM
The following text describes a protein:
Function:
Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.
Sequence:
MGKGYKLTSADGDGPKQCAFFFSDKGCRNGAVCKFSHEAAPPGGGAPSTSNNKTSPSVSSSSVMSSETESDGEIVETRAGAYSSMVAKNDDTNPFFSAVGAVVAPPPPAAVSAVHSAVASINNNATEPPTTEKKKKKRKKRSLSAGENPFELATETQAPNNAATAANQKGIVAPPPSVPQPKKQKATTTPAKETPQQSTSTPNNNATFRNLQLPIASFSLPISTAATTTPAAASKSPRPPSPQHEPAHAAPPLPLPVASANHLKWKNAVIATRDHANYDNAFNFERTKQLEFEQGISTPHHWITTRPYGDWCKNNPASIAIDCEMCETQDPVTGKTDTKALCRLSVINADNPTEVLLDTLVKSEWPVSNYRTWINGIKAKDLEGVQFTLRHAQMFMNALCSEQTVVVGHAVHNDLLALRMIHHCNADTAMLYNHSEEEGGTPSLKNLAYGVLKRDMPEVHDSVNDARVALACADHYCSKNGKVDPVEKVFRRNNGGGRDRDPADTAVLLVHRLPPTSQPGHIADMFLAYTCIKPKNVPEITFSGQHGKCHVEFTSKDHAELAYASLNGEEREDKTGKKQKRVGLKNGSYVCVRKMKKT
The following text describes a protein:
Function:
Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Domain:
The membrane anchor N-terminal domain is required for activity. The iron-binding domain is required for protein stability and function.
Sequence:
MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVNFLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLTYEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKAIDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSIMMGRVFMAKGEYAKAVESLQRVISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAVEENTGADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRAKESLMVLRDMVGEKVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL
The following text describes a protein:
Function:
Catalyzes the sulfuryl group transfer from 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S). The sulfation of trehalose is the first step in the biosynthesis of sulfolipid-1 (SL-1), a major cell wall glycolipid and the most abundant sulfated metabolite found in Mycobacterium tuberculosis, that is a potential virulence factor thought to mediate host-pathogen interactions.
Sequence:
MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT
The following text describes a protein:
Function:
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
Miscellaneous:
MISCELLANEOUS: The reaction proceeds by a bi uni uni bi ping pong mechanism.
Subcellular Localization:
Cytoplasm.
Sequence:
MKVITKVAELRRALADVRNAEKRIGFVPTMGYLHDGHLALISASREHCDVTVVSIFVNPTQFGPNEDLSRYPRDFARDEALCGSAGVSIIFAPSAEEIYPAQFESFVEPGELAKPLCGAFRPGHFRGVATVVCKLFNMVQPDVAYFGQKDFQQCAVIRRMTVDLNLPIEIVTVPTVREPDGLAMSSRNRYLCPEERDRSLAISRGLFAAAHEFASGERDAATLIALARRHLERVDRLQYLELVDPGTLRIADSPLRYPAVLCVAAYVGSTRLIDNVVLSWSPS
The following text describes a protein:
Function:
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
Miscellaneous:
MISCELLANEOUS: The reaction proceeds by a bi uni uni bi ping pong mechanism.
Subcellular Localization:
Cytoplasm.
Sequence:
MLIIRNKQELKEVILKQKQANKTIGFVPTMGFLHEGHMTLVSHARKESDFVVMSVFVNPTQFGPNEDFDAYPRDEAHDAKLAEEGGVDILFVPTVEEIYPTELSTKLHVDKRVSVLDGADREGHFDGVVTVLTKLFHLVSPDNAYFGQKDAQQVAVVSGLVEDYFFPVNLRIIATVREADGLAKSSRNVYLTEKERKEAPVIHEALQLGRKLIESGETNQAKIVQMMTEKINEQTSHELIAYLAIYSYPEFTPVTDWSKGIIIAAAVKYSKARLIDNELINVKRR
The following text describes a protein:
Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MAWHIVQKLVEGVGEHSTLFGKFWITLFFIIRFLFVVTLAESTWTDNESGIVCNTLSPGCKNVCFNAFSPISPIRYWCFQLLATALPPIMIAVSLHFIYKSFQREQSFAWKNXYFDIEIVKQNTQFLHGKYILTYGSKVFMRLVIEVGFMVGQYFLYTYKFVVPELWQCSHWPCPNVVDCFVSRPKEKTIQTCIFYVTGCIMVVLNVIELYHIGGNVGKAWSNRSN
The following text describes a protein:
Function:
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular Localization:
Nucleus.
Sequence:
MSDEDIYDASPPRARNLEVRNKGKRVSDSNEGPSATRRRIRDPSPPNPDANGDLDEYDPAQSMQERRQIQRKLRDMQREMRENPDQFMQDKSSDALINYFDQSDTIMRDVKQTNEATIDSRGLVFAADLSARRAQRLTSGNIGNGIDVDEFVSKCITYMRHGRGFEDDDAPELTSTQRYRRRPGRAAADTEDEEDMGDEGDMLNWPHLGRYAAVPSVRRPALPGFLSGPLSIEKKVRRMTQRNAPFKINSLIEVRPQELRAEDLKKSDKNDLPSICKNILEQLENKQNAAQDAVESLLNNGEVDDPEQEFLIMEKYALHSSGGIDLLRFVINPRSFGQTVENMFYVSFLLREGGLKLEFDSYGRPSLSAHVHADEHEKAQGRHGTTRHQAIMSIDMDIWKDIIDAYNIKEPMIDHREEESQQGPGAQGWYS
The following text describes a protein:
Function:
Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MSSFGKNSSYRDTGASLKELGDYLDSKQEGKPTHQKTIGFDTNTSPVSIPTIISPPLGSNNSNYGKSPKSSYDNKQTSPLLSASNNRKNNNNNNNNNNATSPKDSSIIGKNNVNSDLSKVSSSLNELKFEKQPIGSTSSTPTSTPSSTPSSSTPSSTPSTPNTNSQQQQQQQQQQKKQQQQQPKQPQQPKQQSKQQATQQDKKDKEQQQQQQDKQDKESNEIKGSKEVAKDGQHGVKQFDDPKQRGKITKKKIIKVGESSRSVQLFNHLPQYNSEFSMGVSVSTDEPNEKYPIHPDIISLGLKYAEFKIAGSNARAIAMMTAFIQIFKDYVAAPDKVYSRELDSLLKRNIQFLVDCRPISISMGNSINYVKHKLSLTNNMSHEGARDYLIKSINEFIERIQMADNAIVKHGCSKINDGDVILTYASSHVVELIIQQAIQDKKKFRLIIVDSRPKHEGRELLHRLVLHGVKITYIMLHAVSYIMKEVTKVFVGAYSVLSNGNLISRSGTSLVASMAKFYNVPFIVCCETYKFTERVQLDSICFNQIGNPQDLVQNLGEKEGSKSLLENWESYSTLKLLNLMYDLTPIELIDMVITEFGMLPPTSIPVVLREYRKEVISIN
The following text describes a protein:
Function:
Gap class segmentation protein that controls development of head structures.
Subcellular Localization:
Nucleus.
Sequence:
MSSACSVPASATVNRSLQTQPAGVPSSDNRSVSKSNDPQHINADPTGDGGISYEGRLSLLDPTAVHPSAMDFDQAVVLRRIKAECDMLDFQSIHHHHKDNFMGVDMSLYSAGFSPGSHPANGSAAGLFSSLGQAQQASGAIVDRSAIKTPEYPSTPVRQPQPTTASGMMMDPSGSSGRQQNDSGISPGSTGPAGSTNSSDDNKKRNGHSESCGEDPAAGSVASGSPYSDHYSGDERRMLLTPTEEDDDDMMDGADDDDDLLDEEGSSSRGAGSDVVGEALSRLERALLAQSGGMGGGGVLTEGSSMPSGALYQCNMCSYSAASRFHFQAHLNSHFDVKCTHCDFTARTEGKLRAHIRNAHSDVTGMDDGEMGNTRVPRVSTQGKLKTHKCKHPQCGFVAVTKLDFWEHTKTHIKAEKLLTCPHCPFVTEYKHHLEYHTRNHLNSKPFKCPKCSYSCVNKSMLNSHMKSHSNVYQFRCKDCAYATKYQHSLKLHLRKYNHTSTSNLSLNDSGPMDGFENEVHKVKGRRNAKKPRQSKSVQPANADAMTPTSVSSAVLQGGECGINSNPPPINAGTPPSFALQAFNFPMYPGSHPLMAQQPVGSFEPEKNKIRIPSAEELKCGLCDYATASKDQFSQHLLAHAAADQHHRELANLFGVIPADLLHSPPNPLGHHHQQSVTPLKGSSNTPQQHQMKDYFNWMMANPTLLFSTPTAPASIQQQQQQFTERKKLSEISRTPTPEAPKTAPTPPVSTGPPGKPTQTPLDLSREKDELTPASGPVGPTTNKHRRKGQAFKLERSAAPSTTTTIASPRPVATQSPSPSAPIPAHPRESVEEEIDEEVEEEEEEEAEEEKLLDEDAEMEQDGKAGSPLWRPPSNRNEIRKQRNTKCLPGGGEWGGAYQCSYCDIAFKDVVMYTMHMGYHGFQDPFTCNMCGQSTHDKLAFFLHIARSSHS
The following text describes a protein:
Function:
Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MQIFVKTLTGKTITLEVESSDTVDNVKAKIQDKEGIPPDQQRLIFAGKQLDDGRTLADYNIQKESTLHLVLRLRGGV
The following text describes a protein:
Function:
Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
Subcellular Localization:
Nucleus.
Sequence:
MRKLRKGVARKEGADMANVEGLRRSSRLKRKAEHVLDGGDPVAAPGANASSPRERKRGKRCSLSSQQEKVPDQIDAAASGARAARVRQMTKQASGGLRGRRGRGASSSDGLGTSGTGGDGKEKGADELAPEVEGGELPAGDTAVSDIVAAKEGLRWNQGDFERLTAAKHHGNDRASQNKSGAGDEGERAEKGPEEGTDKAPITTPPGECLPKLVESRTSEGGVDLQLDATPPSSAARLAAALEGFSYRGVSGTPPRRPAHSDCSSGGVRSRLSRGQPSAQKRSANSARFQTPSKSGGSLSTGFPVASPSVSFEAGHSANSSAVGGSAPDQDGDSHRPPRKVSRRRQRATLKVIAQGEKVRETALALIAEGKRVTAEEIRKLIPEEAGKKGTEGRGGGGPKRPAGVVDPDWVPPVSPYGLIQEELWRTPWKLLVACLLLNVTTGGAMRRVIWDLFKLIPTAEAAMAADTDAIGKVIHSLGLQNKRAATIQRFSQEYLEHLKDPLAKPLDRVHGIGKYAADAHAIFCEGRWQEVVPHDHMLNRYWEWMWETQGQGAAFKREDGT
The following text describes a protein:
Function:
Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.
Sequence:
MPSAATASHLAHRLGRLAVCALHAELACAPKPGLVTPFDAGSHTDMDASTFLRSLFALRGYFVAIAQAGIAQAPFEHLRQLGIAAEAAMARATGGINTHRGAIFSLGLLTAQAARLRAVHGRQPSGEQVCCAVQAWSAALQAAPLDSQSHGQRMRAQYRVAGVREQAAAGYPLLRDVALPSLRAALAGGASREAALAQTLMQLIAEVDDLNLLHRGGQAGLAHAQQQARAFLAAGGIAQAGWRAQLARIGDGFVVRRLSPGGSADLLACAWFLHAQEAL
The following text describes a protein:
Function:
Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.
Sequence:
MMSGEHTLKAVRGSFIDVTRTIDNPEEIASALRFIEDGLLLIKQGKVEWFGEWENGKHQIPDTIRVRDYRGKLIVPGFVDTHIHYPQSEMVGAYGEQLLEWLNKHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINMRMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQMAMAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHCVHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFNMLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEPTATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN
The following text describes a protein:
Function:
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of trypacidin, a mycotoxin with antiprotozoal activity and that plays a role in the infection process. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) tpcC. The atrochrysone carboxyl ACP thioesterase tpcB then breaks the thioester bond and releases the atrochrysone carboxylic acid from tpcC. The decarboxylase tpcK converts atrochrysone carboxylic acid to atrochrysone which is further reduced into emodin anthrone. The next step is performed by the emodin anthrone oxygenase tpcL that catalyzes the oxidation of emodinanthrone to emodin. Emodin O-methyltransferase encoded by tpcA catalyzes methylation of the 8-hydroxy group of emodin to form questin. Ring cleavage of questin by questin oxidase tpcI leads to desmethylsulochrin via several intermediates including questin epoxide (By similarity). Another methylation step catalyzed by tpcM leads to the formation of sulochrin which is further converted to monomethylsulfochrin by tpcH. Finally, the tpcJ catalyzes the conversion of monomethylsulfochrin to trypacidin. Trypacidin is toxic for human pulmonary and bronchial epithelial cells by initiating the intracellular formation of nitric oxide (NO) and hydrogen peroxide (H(2)O(2)), thus triggering host necrotic cell death. The trypacidin pathway is also able to produce endocrocin via a distinct route from the endocrocin Enc pathway.
Sequence:
MITVIKWLVSGCCALAAVTTRAPLPKDCRNTPNSRGCWKDGFDILTDYTDPKRAPPGKLVEYNLTVSQQVIAPDGYEKLGMVANGQFPGPTIEADWGDTIRISVYNNFTDNNNGSAIHWHGLRQFENNVQDGVPGVTQCPSKPGETQVYEFRATQYGTSWYHSHFSLQCECPLNGLFGPIVIHGPSSMDWDEDLGPWLLHDWYHDDVFSLLWVGETKNRGAIPESTILNGKGKFDCNHHNDTRCTGTGGEYFEVNFRKGVRYKFTIANTGTLLEYMFWIDGHNLTVIAADFVPIEPYVTDVVNVAMGQRYEIIVEANADFTHGSNFWIYAQYCDEVDLLPHKAVGIVRYDEQDRQDPRTPPLSDQHRDFGCEDPDLDNLVPVVQQSVGRRVNRMEMKDYLRMGQEGYPDPMNFDGDLHKWVLGDVPMFVDWKNPSLKKLAVDEHPDFPPETVPILLDFDTGDWVHFVITNNYTFEKVHFPRNLTPVMHPMHLHGHDFAILAQGRGEFDPSIVPKLDNPPRRDVVNVDTGSYVWIAFQVNNPGAWLLHCHIAFHVSSGLSLQFIEQPKKVKPLMEAAGVLGEFHDRCAKWTEYYDSVNIPDNHTIDDSGI
The following text describes a protein:
Function:
May be involved in the mitochondrial lipid metabolism.
Subcellular Localization:
Mitochondrion.
Sequence:
MFSRSILLRSVRKSLGRYYSSQAHPQTYIYNLLSDTKCRSCGIQLQDKFPDKPGYYRLPGQNDSNTDKKAKTSELNKKYEKILQNLDISDRNLLINNFSAPKQDDEKVASVPSLQQITPVEADTRDTTKDQQTHSGHSLSCKRCNDVIYNSKTRSIYDPNRDNLNKSEFPIPKLQQVLSTIPVDAPLVYVFSANDFPMGINKDIFQYRPPQQIYFVMTKSDILIPKTNVAFYNNFKKFLQNYMFKKFNVPRENVFIASGKDRWKMTDLYHFIPNYSYIIGDTNCGKSTLVKSLLINHHVKHWKYEALQQRPDEKQSSSASLKNKDFKKLDRLIDSFSSKNGPGTSHIPGFTRDVVPVDIDGIKELFDVPGFTTNENLQDIFDKLNHKQIARITKGANTSKYGSLKSKFDTVKNGQVLSLNGVGYLQFPGQDSMYQIRNVTKFALHKFKNLEKVDSILQRNEIPKSMSSHFIVNRQQQQQQRNELRGYYKRYIIPPFYGTIDLVIKDIGYINIKPTGKKLTNELMVLYLHPSLEAIIRQPILNYIDSPTPKKSPDGTNRKTITSDISKTPFYSRLIPSTVLSDPSSLVLSPPSSDYNQLNQYLQIDESSESAYNDLLELDETNKYDYWIE
The following text describes a protein:
Function:
May be involved in some transport function.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKRFDYLTPVGFVLGTIIIVIGIISGSGVSGFRSFLDLTSFFIVTGGLCAAVFISFPPSELKKAPSVLKQAFIRQEDNVKDLVKTFVSLSDHARKHGLLSLDDQAREIKDPFLKKGLLLAIDGWDEETIRLVMDSEIAAMEERHRKGRRVFEKAGEFAPAWGMIGTLVGLVLMLKNLNDPHMLGPNMAIALLTTLYGSLLANMVFNPIAAKLEEKTESEIFIKQVMVEGIIGVQSGKNPRNLESQLVVFSSREEWQKQPKQVKTKKGSVHEA
The following text describes a protein:
Function:
Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration. Binds copper. May be involved in copper trafficking and distribution to mitochondrial COX and SOD1.
Miscellaneous:
MISCELLANEOUS: Present with 259 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Mitochondrion intermembrane space. Note=Imported into the mitochondria via the mitochondrial MIA40-ERV1 machinery.
Domain:
The twin Cx9C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system and the subsequent transfer of disulfide bonds by dithiol/disulfide exchange reactions to the newly imported protein.
Sequence:
MEQNKDPQMISKHSSRLPIWVLSPREEQQARKNLKTETYKKCANFVQAMADCAKANGMKVFPTCDKQRDEMKSCLLFYQTDEKYLDGERDKIVLEKINKLEKLCQKQSSTK
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSSLQQQLSRLSSETIVFSSTGARKNVPSLLYGDNAKSISVETIHEIALAALTELQGIDPSFAAFRANIFHPSAPQYDREAHTEEHNLTFIDKPMSLFLDQVIPYLHLPAAHRAIEFLIRRFRADIKCVEQLVMAFLPYHETVIFSYLVTCLFSMNDPEKLPSSHILLLLGRDGWPGPRSILLKQLRRNSYSLYAKLISKVVDLERVSPESCLFYMRFCFAVTYDLLGFPSLGQDQVLLRETLRLVSWALGPKAHSECRDAACLLLLRAPPVLLHGLAESKQGRNVMKLFLLHPVSGDRRRALKVLLGLTHNALENNVPTVLTLTDMLYSLCQGDWVLELTGSAFSDLVNTAAKRKTDDKCRTLLVSFTYIFSDSLFRFTVVPWKSTSVPDKDRPSLLAAFRNGLRSITAALRAIVEGDKQKEKTLRVGLSKLIRHVAFLIAKYTLVDPDPSSNLELQELARLAADIDVRSFASGAMQSVEETSAEPRDSGADVPNRVLALLFGENREEYWMLAPVAAPSGVPCILALDSSSTELRTMGYSQVQVLIEKFVNQKPVNINGLLKTLPLLCTRLLSEGDTKLLETLCGCISHLISSLPRRLSTSLPSDELMTLLSETVFFYKRLISNGMLTDTYLSTLAQLRECLFCLTKEEIGQEYAYLGAHLELLQSPDASHRVLSVEELIFPFGSIAGMLEAVMLSIKNGYASKHSDIIITHVLQIDAAVSEGSKEGAVFEAFISQVLASPGYSHLFVDVLCQHIAGCSAFLLNTAIKHSTSPDVLTRIGTAYVADKDLSAWSTPLFSGSFDKLLASCILHNIFTDQTWVSRAVEHFQSASSKKASKRSSAKASRGSSKRESTVIQSPNVEGNSTCDPDFLIACAFYVLDNKDEQGTELLRTASQGLHLLGSKISKDIYGPICEALQSALGTGEPFDLSGSITELLTLIAGSTRMCHVFIAQFISKALICCIDQCEEGSNPVEMLTDIAMFINNASSESSPTTMVLFGHALEKSVLTLLGRLSYTDRIGMLLLPDHGDCADPMISTFCEQSSLSPNFLQTSLSSSRMTNPVKSSLINLAESCYVCMVSIADSITDKEVSACEIPLQQARLYAVLAVLGTIPELVSLSHDISSLAFILLGGCDCASVPEELATIYKDLAVSSFEYLLPIPLSVATELRRLASDYVSRAPLAVAYVNDYISTFPIEFLESLTRRRHLIDDPGALLSILIAQIAGGDIQINPESRREVLILRLVLRMMSFSSSDRSIDSYQEKNVYGEFADKDQKTPEDDDNSKTLSLLRSLEAFDQMSCIVPSQTDAESLSGLCFYHPELLACAQTVAPDRFQTLFIARMVNRLTAEPYPSPLPPEKISQVIINLFQLATKIYPDTSLFWSTAVTLIRTSVDLTSRELISALDQQRIFLAILSLTEQVHHSIYLLIFILSNIYSKANDTETKKAPKVLQDQLIGHFVTRVDMERQLQALYLLCHGVVWNFLKTGVHEQNLEDAINVLSKTAHCIDPDRKMLESSATMRSLGFSLLFDDLSSSLNFLNRNVSEEEDVNSVFEDNPVGGERGNSEQDDEAVACEDNFLSTLLIHVMREIWKIRSIDGTEKSLKKKAQSDPALMGALKAVQMSIDTMIVYLDTYAFYVTTQTEQSVVRYAMSSIIGASILRVNDKERGSKLLEKLVANLSVTSLSMACVKLYQNILDGINLQQPCVTLFLLLRQKISGTLEGRRVDVEDVKQAFLVLYNVFVDVIAEDVDRDLKKLILDVLVEFCTGFPTVLDPAAAVAITKAISSAEFYVSLSSLTDGASNILHGSLYALGHLVEACDCSIIPVLKELVPPLLGYLNAQVVREGISARMESFDVSFYSETTLAVVTVLSSLMISQGRFMTPYLSEVITLLCILCPLGPCVGEVFAIDNDSASPQDIDVKLDVVRRVFKALLPELPMETRHGITDYALKILTTAVAGLSAISRVVALRLLLPAMHVVLDKYVVLVRKYALQYVEPLVHAITLVLYPTLSEAVLTNELRVDVVKFVLSVVAMRADNSCYPLLFSQYDRLETCAIYLLAELDLKMQEKSLGGVIEQCWSWCMECTSNSLTEDNTGDARATKFNLSLFGSLFEKTYTEAVTSIQLTSPPSVPRMTACAHILAVLGGQDPQRLVTGVGKLLYEVIGTYLFAITSPLGCVPYSLDTKTIAQLLDTRQRAVELSSAPMGMFITCGLESSASISGIAEDSFYEVYSMGRYFNLFLFACGHVVGALRDDVYIAAISFMVAIVCSAVAPCNELKDVVYPSLKVALQAVEGNNNTPMLWEYLHDMSITLTKNSNDAFRLRGIELLEVFLCVVLPHDTHWLTRAAGVIDEAIEDLHEGVSAAAQHLIRSVESVTGKLYRDLVSAGV
The following text describes a protein:
Function:
Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected, using 5'-AMP as the substrate, in the presence of diverse divalent metals and with various pH values.
Subcellular Localization:
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase SrtD.
Sequence:
MLSVEMISRQNRCHYVYKGGNMMRRILHIVLITALMFLNVMYTFEAVKAAEPQQPISIEKAIQQKEGQALVEGYAVGQAVSPQHYKLTSPFSNDYNVALADRKNKTSPEHILPVQIPSAFRSQFGLQTNPLLLGKKITVQGKLENYFNTTGLKNVQSMNVTDDTKTPPAEQQVTINEARGRLNEEVTIKGIITADQNAIGGGKLSTFLQDETGGINIYSPSPEQFPELKEGMDVTVTGKITSYQGLKEIVPNSSGIKINQSNQSLPAPKHLTINELINGSLGDQYEGRLVKLTAFVSSIPSSPAGGGYNVTMIDDDHHAMTLRVMNETGVINELDEGKWYEFTGVLSRYQTFQLLPRKSADLKLLEEQPAPPSAEGEYEGIVDRVVDGDTIHLKSPVLGTTKIRFVNVDAPETYHTPKNDADENQLRFGKKASDYLKTVLSPGDKITVKVGSEAKDSYGRLLGQVITESGSNVNLELVKNGYAPTYFIWPVDNEEDYQQFQAAVAAAKKDQKGIWNENDPLMEMPFEFRAREQGKGLTRYVGDSSNKTYVQPADWKKIAVENRIFFASASEAESAGYKKRQTAPQEHVPLRILSMNDLHGKIDQQYELDLDGNGTVDGTFGRMDYAAAYLKEKKAEKKNSLIVHAGDMIGGSSPVSSLLQDEPTVELMEDIGFDVGTVGNHEFDEGTDELLRILNGGDHPKGTSGYDGQNFPLVCANCKMKSTGEPFLPAYDIINVEGVPVAFIGVVTQSAAGMVMPEGIKNIEFTDEATAVNKAAEELKKKGVKAIAVLAHMSAEQNGNAITGESADLANKTDSEIDVIFAAHNHQVVNGEVNGKLIVQAFEYGKAIGVVDVEIDKTTKDIVKKSAEIVYVDQSKIEPDVSASAILKKYETIAEPIISEVVGEAAVDMEGGYSNDGDTPLGNLIADGMRAAMKTDFALMNGGGIREALKKGPITWGDLYNIQPFGNVLTKLEIKGKDLREIINAQISPVFGPDYSISGFTYTWDKETGKAVDMKMADGTEIQPDATYTLTVNNFMATATGAKYQPIGLLGKNPVTGPEDLEATVEYVKSFDEPIAYTKEGRIKLAEASDIEDPVTEDPITEEPGDDPGTEDPIKEDPRPGEDLPDIKETPGTAPVHQLPPSAISRFNEIPINNTKTADTANSISTLPLQTETAESGSDHQLPDTSAGYYNFMVIGAAVTLSGTYLYVRRKRSASRT
The following text describes a protein:
Function:
May be required for assembly of mitochondrial respiratory chain complexes.
Subcellular Localization:
Mitochondrion intermembrane space.
Sequence:
MAGLVDFKNEEEVKDYLDNLGTEYSYQCFKEKQPDGCNRLAEYFENIKKNFESAAGILKINCDQNEHSESFYKLGAYYVTGKGGLPVDLKAAYSCFLKSCNKGGKKSIDSCHNVGLLAHDGRVNDEKADAVTARDYYNKACDGNFAASCFNLSATYLQGAPGIPKDMNKALHFSEKACSLGHVWGCANASRMYKLGDGVAKNDEKAESLKNRARDLHKMQQERTPQISFGE
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, flagellum basal body.
Sequence:
MDNADQEIDTKQEELRRKKQEKLLAKKAAAREAQNQLYRDHLKRERDFSDQTERAFFADWETLCAQVQSGQLVEELRQQQQCFGTVFDRKNECIRRLVGAQEEVQEIHTKCLARLGNVLDYYIRLKDFLTATVLEHYESESQKLLKEFREEVESKESFSTSQMELLDASLAELLSKIKLDESNDREWLLAANNQNISAQVEKCEIIRDHKFTEMSALYRQLRATLDDYFQTVLYPERQAAYHGLVQRTEDDDKIFNKNCCEMAVLQSKKTQLEHTLKLARIGARRKLRTRHNYRRLLEMKVLLLKKQQQQLDDEHQRCLKWICSFTHQLRKLLAEHFAWGERIAKMALICTQYETEQDQRYAARWFQPEPDEGKRLHQPEAHDGTFDYLIHKINRVEAINIVLREEKLRLKRENDELQTKFKAYCGLHNITAPEKLHLCGRGADERTSQP
The following text describes a protein:
Function:
Acts at least in part as component of the WASH complex which may regulate wash nucleation-promoting factor (NPF) activity and is required for its membrane targeting during endosomal sorting (By similarity). During embryogenesis, not involved in the wash-dependent developmental migration of hemocytes anteriorly from the tail.
Subcellular Localization:
Early endosome.
Sequence:
MSFLDDNNACGQNLLNIVSVGNSIIAEILRLKDYVPSIYRLDNKADKAKYGELILDFSYFKIAEDHERRIEQSPELTELDDEARAQLPLITRFYLAFQSIHHYASDLQQYIEELNTGYYIQQTLETVLQEEEGRQLLCESLYLFGVILLMVDFHIPGDVRERLLIAYYRYSGGDATPSGDESNIHDVCLLLRSTGYVHPSIAAKVLGLGGKQAGARAASLVVPRYPEAYFSRFRFDENFVDLVVARLRCDDIYNQLNLYPHPAHRSTALSTQAAMLYVCLYFCPQVLHSQGSQMREIVDKFFCDNWTISVYMGMTVNLVDAWLDFKAARSAIENVISPPAIKALCQQQKEQLGKITQKTQEIVREGVLNDNFVLEHANKIIHLMRQSNVLLRWFCLHTSREVFIFAHTATLTGQVQKCVLHELQFNRNTLYNLLLNCSQMELSVREFLAEIQQTKEERWTKSREEAMQRLNELSEAFAGSRPLSKIEQNPQLQQWFGEVAGRLQKLELSRPQKSGRLIIQVMQALDDVQEYHNLHSNMLVKQQLQETRDMLNQMAQLINLKEDIEIHIQMITDFSYAWHLLQFDFTPPMQEHIKRQPQAVIGIRAVFLKLASTLEVPLMRINQARSEDLVSVSNYYSTELANFLRRVLQIVPETMFSILAKIIYLLTNVIKEFPTKVEKERLKDYAQFEERAKVAQLTNSIAVFTKGILMMKTTLVGVIELDPKQLLEDGIRKELVNHLANAYNLGLIFTPEKGKTPVQLLQQKLQALAKTIEGYRRSFEYIEDYLRVQGLRILLEESQRIINYNVEKECNAFLRNKVQEFQSEHQSQIIPIPNFPPLLGDPSNNFIGRLAHEILRCTDPKQTIFLDLKSTWYEKKAPHQEVLAGSGFFEILREALAPAGMVGLERLYAHMLADELKRNLERLQRNLTSDRMWVDTLAALTRELEARDFPTPEVSKQPLKYYQAYTQRWLKVWPTLLDWVLCIGQKQLLRREIAGELSFSSKCDAKLLENTADTLNKALLLELSLSKDLCDEKGVVMLTELQETLLYTGNFEPLEQVFLITKNTHNMALFMFLFTIAHLGRMQHSTITDCLLPKSAKDNIDNVPFIVGLVTILQQFHKNVKMLYISYMSQYVVTVSEAQLLDKEILGPEVVTALHFLLAFIRIARLPLGVLEQRIPNIILSEYEYLSTLLK
The following text describes a protein:
Function:
Probable transcriptional regulator involved in cell adhesion.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MADPGLRSGVGLPSQQGQKHDLQKDQKQPHVNNADRTTQSLLNSYIYDYLIKKDYCEAARAFGREAQVQTLVRSQEETNSLAKRHKRMSPVAVKHEGISNNESSDENMNVNNGNLDSFSSSSAPPPPPILPIDSAGGFLIEWWNVFWDIYNARRGQGSEPAKAYMSHISNLRKKSRLNLQEIQKNSLHTGNTSHPYANASFPHDPANAMGQQIDSSQFHQGAGGLNDRNQHLMRQAMLNNQSRETFPPTAAQLQQLKQLHYRQLQSVQQQQKQHQQKKTPQSGSTPQMQNTTSQPTTHDTHPPKQQGPISDFRSIPSSPKTEGAPSNAQFRPSLPATPNGSVPQSNPLYDTTGLNGGQYPVVQNSAQPLLHEINFASNRNPHLKQGGAVPSSTLPQQQKSLDKPKPAQQPSTGQFSGNQMNQYGFSNSPYSQNMLYNFNGNANPSRLNPALKNYMEELKLLEQQNKKRLLLVSQEKERKGYTSASPDRPLSQTITESSVAKTKSTTPKSTDTPTEATTSPVKVSTKNSNTTENLNGINESNMPMLQNGLPLRTSGDHPSNYSNLIENSSTSDTNNADNGMDVMGNWQLQQTHSSRPTPNASSPLDVRSKQKPSSANSNAPTPAPTVNTTNPESSTNEATSVGPALEPSQGANVHKSDSELDNQNQSGKSNPDTSATPSAPTESTTVATKSSDNQLLDVGNSTDIDAALLNDFDFDKFLKDTSTGDDLWFGLFNLPDNEDSTAA
The following text describes a protein:
Function:
Interacts with photosystem II (PSII) core complexes and participates in the maintenance of normal PSII activity under photoinhibitory stress. May protect against photodamage or stabilize PSII under high-light stress. Participates in the maintainance of proper PSII function under high-light stress by protecting PSII from photooxidative damage.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MSNVLLSPNGYVFASPKPLGRFINSKSGGRKLFFSVVRASSDDADCNAEECAPEKEVGTVSMEWLAGEKTKVVGTFPPRKPRGWTGYVEKDTAGQTNVYSIEPAVYVAESAISSGTAGSSADGAENTAAIVAGIALIAVAAASSILLQVGKDAPTRPKAVDYSGPSLSYYINKFKPSEIVQPSTPSVTEAPPVAELETSLPETPSVAQQETSLPETMASEAQPEASSVPTTSSTS