lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Regulates chlorophyll synthesis and plastid-to-nucleus signal transduction by binding both the product and the substrate of Mg-chelatase, an enzyme that produces magnesium-protoporphyrin IX (Mg-Proto). Also activates Mg-chelatase. Neither binds abscisic acid (ABA) nor is involved in ABA signaling.
Subcellular Localization:
Plastid, chloroplast membrane; Peripheral membrane protein. Note=Might be bound to membranes by specific protein-protein interactions.
Sequence:
MATTNSLHHHHHSSPSYTHHRNNLHCQSHFGPTSLSLKQPTSAATFSLICSASSTSSSTTAVSAVSTTNASATTAETATIFDVLENHLVNQNFRQADEETRRLLIQISGEAAVKRGYVFFSEVKTISPEDLQAIDNLWIKHSDGRFGYSVQRKIWLKVKKDFTRFFVKVEWMKLLDTEVVQYNYRAFPDEFKWELNDETPLGHLPLTNALRGTQLLKCVLSHPAFATADDNSGETEDELNRGVAVAKEQAGVGADKRVFKTNYSF
The following text describes a protein:
Function:
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Domain:
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
Sequence:
MAIPLVLVVLPLGLLFLLSGLIVNAIQAVLFVTIRPFSKSFYRRINRFLAELLWLQLVWVVDWWAGVKVQLHADEETYRSMGKEHALIISNHRSDIDWLIGWILAQRSGCLGSTLAVMKKSSKFLPVIGWSMWFAEYLFLERSWAKDEKTLKWGLQRLKDFPRPFWLALFVEGTRFTPAKLLAAQEYAASQGLPAPRNVLIPRTKGFVSAVSIMRDFVPAIYDTTVIVPKDSPQPTMLRILKGQSSVIHVRMKRHAMSEMPKSDEDVSKWCKDIFVAKDALLDKHLATGTFDEEIRPIGRPVKSLLVTLFWSCLLLFGAIEFFKWTQLLSTWRGVAFTAAGMALVTGVMHVFIMFSQAERSSSARAARNRVKKE
The following text describes a protein:
Function:
DNA-binding protein involved in the repression of transcription of a large number of genes, thereby arresting growth, in response to environmental changes. Binding sites are identified in promoters of approximately 200 transcription units, including genes involved in ATP synthesis, transmembrane transport, translation and DNA synthesis.
Sequence:
MRVPLDEIDKKIIKILQNDGKAPLREISKITGLAESTIHERIRKLRESGVIKKFTAIIDPEALGYSMLAFILVKVKAGKYSEVASNLAKYPEIVEVYETTGDYDMVVKIRTKNSEELNNFLDLIGSIPGVEGTHTMIVLKTHKETTELPIK
The following text describes a protein:
Function:
Catalyzes the addition of a mannose residue from GDP-D-mannose to GlcAGroAc2 to generate 1,2-di-O-C16/C18:1-(alpha-D-mannopyranosyl)-(1-4)-(alpha-D-glucopyranosyluronic acid)-(1-3)-glycerol(ManGlcAGroAc2).
Sequence:
MRVAIVAESFLPNVNGVTNSVLRVIDHLRRTGHEVLVIAPDTPRGQPPADRIHDGVRVHRVPSRMFPKITSLPLGVPRPRMIGVLRGFDPDVVHLASPALLGYGGLHAARHLGVPSVAVFQTDVAGFAESYGMGVASRAAWAWTRHLHSRADRTLAPSTSAMENLAAHRIPRVHRWGRGVDITGFVPSARDEHLRRTWSPDGRPIVGFVGRLAPEKHVERLAVLAARDDLQLVIVGDGVDRVKLQTVLPTAVFTGELRGAALAAAYASMDVFVHPGEHETFCQTVQEAMASGVPVIAPDAGGPRDLVAPCRTGLLLDVDGFECALPAAVTHLIAERRRYGIAARRSVLARTWPVVCDELIGHYEAVLGRRSLRAA
The following text describes a protein:
Function:
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
Subcellular Localization:
Nucleus.
Sequence:
MEEESISGLEVRFYQTQCLSEDNVIKFENNGYPMIDLILFSDAYQIQRNTSIPIETVTLIQRNLQRLFSSVPINGYQHYLDVKEFKTHYSSGIKLLDQLLGGNGFTSGEIYELVGNTSCGKTQISMCCSLNLSQQYNSNIIYIDSSNSFSPPRLIEIFKSNYLIKQRQKQQQKQQQKQHQKQQENNDKIEQDKILKILDRIKVFNCFDSITLLELLSTIDSTLSIISDEIPTFENQFYKGLKMVVIDSIGTLLAPIIGGKQTQGHYTMMMISRLIKYIADTYQIIFLITNNTVGGNSFDNKAALGEAWSMVPNHQLMINHQYNDDENEERSIYIEKSTRLPVSIIFIINLYWLF
The following text describes a protein:
Function:
Involved in rRNA-processing and ribosome biogenesis.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MRQKRAKTYKRVMTLYTQTFGFRQPFQILVSQDLLLEGAKSELNMPKQFVTVIQGECKPMITQCCMEALYKLGKPVQRTTDLAKTFERRKCNHRTALEPDECLKDVIGATNKHRYILGTQSTTLLTAMDRIPGLPVIHFNPRGVLVLSPPSTATIREKNKVEEERRLEGVKVLEGVVDGGNVVGADLAPVSGGPAEKRSRKVKGPNPLSVKKKKTPGQDKEGESKKRRRVEEEEVKEDENEVNAEGKRKRKRKKKKTAVGEAIEELNATNADRTEKAVVSDDSDGSEEE
The following text describes a protein:
Function:
Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
Subcellular Localization:
Cell membrane, sarcolemma; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MHKSTKIKIAVFVLFVGMACMFTAVVTDHWAVLSPQIEKVNQTCEAAHFGLWRLCKKFIYLSSENFVMGHGCGPISLPGEENCTYFRHFSPGQNTEIFEYKTQKEYNISAAAISIFSLAFMILGSLCLLGWCTGKGKGRDYLLKPAGMFFAFAGLCAFISLEVMRQSVKRMIESEDTIWIEYYYSWSFACACTGFVLLFLCGISLLVLSMPQMPRNPWETCMDAEPEQAE
The following text describes a protein:
Function:
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA.
Miscellaneous:
MISCELLANEOUS: [Isoform 1]: GPI-anchored form.
Subcellular Localization:
[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor; [Isoform 2]: Secreted.
Sequence:
MGLLRRRLLLLVVVVTTCVPASQGLRCIQCESNQDCLVEECALGQDLCRTTVLREWEDAEELEVVTRGCAHKEKTNRTMSYRMGSVIVSLTETVCATNLCNRPRPGARGRPFPRGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVTLQSTERSVKDEPYTKGCGSLPGCPGTAGFHSNQTFHFLKCCNFTQCNGGPVLDLQSLPPNGFQCYSCEGNSTFGCSYEETSLIDCRGPMNQCLEATGLDVLGNRSYTVRGCATASWCQGSHVADSFQTHVNLSISCCNGSGCNRPTGGAPGPGPAHLILIASLLLTLRLWGIPLWT
The following text describes a protein:
Function:
Could influence the NAM7/UPF1 function, possibly at the level of mRNA turnover. Participates in mitochondrial biogenesis.
Sequence:
MIASEIFERGVQDPFCQDCDYEDETDVQSFLGSNDLNDFVNSKLASFSFQNSSKSNNSHHSSSTNAGNTSRHIGNHTIGHHLRKIKTAPHHLYGFVPANSTNNSNEPIRPSPRRIRANSSTLIHQLSRQSTRQSSLGDAADSCFDHKCIKPRSRHSSCYGIPTHLYGLEKYVSSELDSLAVANDQSNDLTSPLTSVSTPASNSNSYLNLNSSSAAYPSSYLSNEKNNRLKLISHGKISSNNVPGHSGNLNHYHRERTPSNLRRESFSLLSNGSSSSPLQTRNNSYSNSLVKSPSNSSLNTSVASSNEESSPHTSNCLEERNPRRKSFIKLSLASSFSN
The following text describes a protein:
Function:
Transcription factor involved in endoplasmic reticulum (ER) stress response. Acts downstream of the ER stress sensors IRE1, BZIP39 and BZIP60 to activate BiP chaperone genes.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: Potent transcriptional activator. Induced by IRE1 in response to endoplasmic reticulum stress. IRE1 cleaves a 20-bp fragment causing a frameshift of the mRNA transcript.
Subcellular Localization:
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein; [Isoform 2]: Nucleus. Note=The bZIP domain is translocated into the nucleus in response to ER stress.
Sequence:
MDVEFFADLDLDALLASFSSSAAAAGSGVSGLFAPSPPHDAEAGSPESVSSRRPSPSREAALSEIERFLMEEGPAAEEGVGAEDFFDALLVDGGEEEEEEEGKGSEAGGSTDGDSGKENEVATPDAEKEDVEAEVDGDDPMSKKKRRQMRNRDSAMKSRERKKMYVKDLETKSKYLEAECRRLSYALQCCAAENMALRQSLLKDRPVGAATAMQESAVLTETLPLVSLLWLVSIVCLLPVPGLPNRNPVARSSAGRDLATVTGKKTSSEQQLEETLLLHGRRCKGSRARIKLDTGPFRLAAAAC
The following text describes a protein:
Function:
Cell surface proteoglycan that bears heparan sulfate. Functions as a coreceptor for growth factors and morphogens, such as the products of dpp, to regulate signaling and distribution of these ligands. Required for cell division patterning during postembryonic development of the nervous system. Plays a role in dpp/BMP signaling possibly by stabilizing dpp and thereby creating a morphological gradient during wing development. Might have a role in testis development. Functions with magu and fwe in a mechanism of scaling, which utilises apoptosis to ensure that the dpp patterning gradient remains proportional to the size of the growing wing. In this mechanism, fwe represses dally and Magu-dependent activity in expanding the gradient, and dally/Magu inhibits fwe-dependent apoptosis to keep cell death rate low. When the levels of these different proteins are optimally regulated the gradient correctly scales with organ growth but when this fails, fwe-mediated apoptosis is activated to trim the developing tissue to match the correct size of the gradient.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Note=Localizes to the apical side of wing disk epithelia.
Sequence:
MAARSVRLAQLLLFTLLCGFVGLSAAKHLDLDGIHHHQHHLHSATTHHRRRLQRDSRAKDAVGGSTHQCDAVKSYFESIDIKSSGTYSEKGAICGGNCCNNATELELRDKAAGMFEQLLHHHTSSLRGVLETNAKQFQSHVLELAQISENMTHSLFSKVYTRMVPSSRMMIHQLYTEIMNHLIYTSNYTNSNGQLGRRGIGSVQSNLEEAVRHFFVQLFPVAYHQMVHLSKNNLGDLHEDYVNCLQHNFDEMHPFGDIPQQVQSNLGKSVHMSNVFMNALLQAAEVLSEADALYGEQLTDTCKLHLLKMHYCPNCNGHHSSSRSETKLCYGYCKNVMRGCSAEYAGLLDSPWSGVVDSLNNLVTTHILSDTGIINVIKHLQTYFSEAIMAAMHNGPELEKKVKKTCGTPSLTPYSSGEPDARPPPHKNNVKWATDPDPGMVLFLSTIDKSKEFYTTIVDNFCDEQQHSRDDHSCWSGDRFGDYTQLLINPGTDSQRYNPEVPFNAKAQTGKLNELVDKLFKIRKSIGAAAPSNSIQATHDIQNDMGEGSGGGEGQIGDDEEEYGGAHGSGDGSGDGPHTPIEESEGTTTNEVESRDSGKTSGSNPLEGTATWMLLTLVTMLFSSCS
The following text describes a protein:
Function:
Palmitoyl thioesterase specifically expressed in the endoplasmic reticulum of neurons. Modulates the trafficking of the glutamate receptor, AMPAR, to plasma membrane through depalmitoylation of GRIA1 (By similarity). Also regulates AMPR trafficking through the regulation of SACM1L phosphatidylinositol-3-phosphatase activity by interaction in a malonyl-CoA dependent manner (By similarity). Binds malonyl-CoA and couples malonyl-CoA to ceramide levels, necessary for proper spine maturation and contributing to systemic energy homeostasis and appetite control (By similarity). Binds to palmitoyl-CoA, but does not have carnitine palmitoyltransferase 1 catalytic activity or at very low levels.
Subcellular Localization:
Synapse. Cell projection, dendrite. Cell projection, axon. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localized in the soma and dendritic and axonal projections.
Domain:
CPT1 enzymes are comprised of an N-terminal regulatory domain and a C-terminal catalytic domain that are separated by two transmembrane helices. In CPT1A, the regulatory domain, termed N, adopts a malonyl-CoA inhibitory and non-inhibitory state, Nalpha and Nbeta, respectively, which differ in their association with the catalytic domain. In CPT1C, the inhibitory Nalpha state is structurally homolog whereas the non-inhibitory Nbeta state is severely destabilized which probably contributes to the low catalytic activity of CPT1C relative to CPT1A and makes its association with the catalytic domain unlikely.
Sequence:
MAEAHQASSLLSSLSSDGAEVELSSSVWQEIYLSALRSWKRNLWRVWNDFLAGVVPATPLSWLFLFSTIQLACLLQLDPSLGLMEKIKELLPDWGGQHHQLQGLLAAAVFASCLWGTLIFTLHVALRLLLSHHGWLLEPHGTMSSPTKTWLALVRIFSGRHPRLFSFQRALPRQPVPGAQETVRKYLESMRPVLRDDAFDSVVALANDFLRLQAPRLQLYLQLKSWCASNYVSDWWEEFVYLRSRGSLVNSTYYMMDFLYVTPTPLQAARAGNAVHTLLLYRHLLNRQEIPPTLLMGMRPLCSAQYERMFNTTRIPGVEKDYLCHLQDSQHVAVFHQGRFFRVGTHSSNGLLSPRALEQQFQYILDDPSPACPLEEHLAALTAAPRSMWAQVRESVKTHAATALETVEGAAFFVSLDSEPAGLTRENPAASLDTYAHTLLTGQGHDRWFDKSFTLIVFSNGKLGLSVEHSWADCPVAGHLWEFTLATECFQLGYATDGHCKGHPDPALPKPQRLQWDLPKQIQPSISLALRGAKTLSGNIDCHVFPFFHFGKSFIKGCHVSSDSFIQLVLQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACQFVRAMENKERTDQQCLALFREAVDKHQALLKAAMSGQGIDRHLFALYIMSRLLHMQSPFLTQVQSQQWLLSTSQIPVQQTHLFDVHNYPDYVSSGGGFGPAHDHGYGVSYIFMGENAISFHISSKQSSTETDSHRLGQHIEDALLDVASLFQAGQQFKRQFTGLGESSGWKYSNLSCKTVDPNIPKSSTNL
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MPDKWDEESSSEESSDPTPAQAAASTRRKFDDEEDDDEVLDSWSAAEDSEVEREKAKVEAERKAKADALAAANKKSKKERVAEKQAERARQLAENSDESSEDEATRRERLRRTEQESDLKHAEDLFGNIGINSRKSTSAANAVQVDEKNPAATVDLTTLPLFDPRTKPQFEKLRETLVPLITNNVKKAQYIIFLQEFTKQISKDLPSDQIKKIASTLTALSNEKMKEEKAAEKGGKKSKAQKTKTTLNASRDAISHKDTQAYDDDFGDDDFM
The following text describes a protein:
Function:
Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Membrane.
Sequence:
MAVAKDTERDVQENILVRTFRETRSELRQVVWPSREETIRLTMLVIAVSIVIGLLLFIGDTIFTFLYTSLVSLVQ
The following text describes a protein:
Function:
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MAVDPRVLQQEAEKTLASASKGWGLFGNKEDKYQNAADQYIQAANAFRLQKSNTEAGKCFEEAAKIFTEKLKEPNDAANAMLDAFKVYRKDAPDNAVRCVEVAIKQYTMAGNFRRAASHKENQAEVYENELQNKPEAIKAYTTAAEWYENDGAVALANKLWLKVADLSALAGDFFAAIEKFEKVAEASLGNNLMRYSVKEYFLKAGLCSLATKDMVTAQRNITKYAEKDPSFTGQREYQLLVDLLEAASNNNLEMFQDKLAAYDKMSRLDDWKAAVLLQIKNNFEEADNEFS
The following text describes a protein:
Function:
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
The following text describes a protein:
Function:
Methyltransferase that catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion, including tRNA(Leu) (deciphering codons UUA or UUG), tRNA(Lys) and tRNA(Ser) (deciphering codons UCA, UCU, UCG or UCC). Catalyzes the formation of 1-methyladenosine at position 947 of mitochondrial 16S ribosomal RNA and this modification is most likely important for mitoribosomal structure and function. In addition to tRNA N(1)-methyltransferase activity, also acts as a mRNA N(1)-methyltransferase by mediating methylation of adenosine residues at the N(1) position of MT-ND5 mRNA, leading to interfere with mitochondrial translation.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLMAWCRGPVLLCLRQGLGTNSFLHGLGQEPFEGARSLCCRSSPRDLRDGEREHEAAQRKAPGAESCPSLPLSISDIGTGCLSSLENLRLPTLREESSPRELEDSSGDQGRCGPTHQGSEDPSMLSQAQSATEVEERHVSPSCSTSRERPFQAGELILAETGEGETKFKKLFRLNNFGLLNSNWGAVPFGKIVGKFPGQILRSSFGKQYMLRRPALEDYVVLMKRGTAITFPKDINMILSMMDINPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHWRDSWKLSHVEEWPDNVDFIHKDISGATEDIKSLTFDAVALDMLNPHVTLPVFYPHLKHGGVCAVYVVNITQVIELLDGIRTCELALSCEKISEVIVRDWLVCLAKQKNGILAQKVESKINTDVQLDSQEKIGVKGELFQEDDHEESHSDFPYGSFPYVARPVHWQPGHTAFLVKLRKVKPQLN
The following text describes a protein:
Function:
Specifically catalyzes the glycosylation of the pilin-like competence factor ComP.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNSIFKKIKNYTIVSGVFFLGSAFIIPNTSNLSSTLYKELIAVLGLLILLTVKSFDYKKILIPKNFYWFLFVIFIIFIQLIVGEIYFFQDFFFSISFLVILFLSFLLGFNERLNGDDLIVKKIAWIFIIVVQISFLIAINQKIEIVQNFFLFSSSYNGRSTANLGQPNQFSTLILITLFLLCYLREKNSLNNMVFNILSFCLIFANVMTQSRSAWISVILISLLYLLKFQKKIELRRVIFFNIVFWTLVYCVPLLFNLIFFQKNSYSTFDRLTMGSSRFEIWPQLLKAVFHKPFIGYGWGQTGVAQLETINKSSTKGEWFTYSHNLFLDLMLWNGFFIGLIISILILCFLIELYSSIKNKSDLFLFFCVVAFFVHCLLEYPFAYTYFLIPVGFLCGYISTQNIKNSISYFNLSKRKLTLFLGCCWLGYVAFWVEVLDISKKNEIYARQFLFSNHVKFYNIENYILDGFSKQLDFQYLDYCELKDKYQLLDFKKVAYRYPNASIVYKYYSISAEMKMDQKSANQIIRAYSVIKNQKIIKPKLKFCSIEY
The following text describes a protein:
Function:
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
Sequence:
MNKTELIAKVAEKQGVSKKEGAPSVEKVFDTISEALKSGEKVSIPGFGTFEVRERAARKGRNPQTGEEIDIPATKAPAFKPAKALKDAVKAK
The following text describes a protein:
Function:
Plays a pivotal role in regulating the expression of other pair-rule genes such as eve, ftz, and h.
Subcellular Localization:
Nucleus.
Sequence:
MHLPAGPTMVANNTQVLAAAAAAAAAAAAAVAQGPGPQQSSNATTASAIAINPAQSLANTSTHSASSTGSSTPDLSTNNTSSSSNATTSPQNSAKMPSSMTDMFASLHEMLQEYHGELAQTGSPSILCSALPNHWRSNKSLPGAFKVIALDDVPDGTLVSIKCGNDENYCGELRNCTTTMKNQVAKFNDLRFVGRSGRGKSFTLTITIATYPVQIASYSKAIKVTVDGPREPRSKQSYGYPHPGAFNPFMLNPAWLDAAYMTYGYADYFRHQAAAQAAQVHHPALAKSSASSVSPNPNPSVATSSSSAVQPSEYPHPAAAVAAAAGQPAAMMPSPPGAAPATPYAIPQFPFNHVAAAAAAKAATPHAFHPYNFAAAAGLRARNAALHHQSEPVHVSPASSRPSSSSPTQQHVLLKLNTSIETSSIHEQSASDGDSDDEQIDVVKSEFDLDKSLDVAPLRMRCDLKAPSAMKPLYHESGPGAVANSRQPSPETTTKIKSAAVQQKTVWRPY
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Sequence:
MCTRNKKDITTEYLNSKKIDRELKQESTTLQPLKLLLLGSGECGKSTIFKQIISFQDEATKKEYTPPSDYVIKNIFLNILTATSTFVRVAPSYNIEFSEEENQKIQSILNVFSDLENLDQTVFTSVSDNIKYLWNSKQIQSIYNNTNRIFQLNDSTEYLMSNIDRYSKPFKPTQNDFLRVRVKTTGIVEADFKIEAVPFKLVDVGGQKNQRRKWIHCFQDITCVLFVTSINDYDTLLEEDNSTSRFTDSLELFREMVNSNWFTKSPFVLFFNKIDLFKEKIKRIPVSQHLKDFNGNDHSYEETSQFIKNKFHTTIKNSNKIVYHHFTCALDSRAIEVVFNSIQHSLLMNVAEIL
The following text describes a protein:
Function:
Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity).
Miscellaneous:
MISCELLANEOUS: Present with 8120 molecules/cell in log phase SD medium.
Sequence:
MSQEFVEDYSRTGSSDDEDSGAYDEWIPSFCSRFGHEYFCQVPTEFIEDDFNMTSLSQEVPHYRKALDLILDLEAMSDEEEDEDDVVEEDEVDQEMQSNDGHDEGKRRNKSPVVNKSIIEHAAEQLYGLIHARFILTKPGLQAMAEKFDHKEFGTCPRYYCNGMQLLPCGLSDTVGKHTVRLYCPSCQDLYLPQSSRFLCLEGAFWGTSFPGVFLKHFKELEEYVERKSKESYELKVFGFRINDEAVSGPRMKWLRQYPSTEEDWEEFAKCEFETPAV
The following text describes a protein:
Function:
Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
Subcellular Localization:
Cytoplasm.
Sequence:
XTQDTNSWFLCRGLRASGVSVRRVAVVPDDVGEIAAEIAAMAPRHTFLLTSGGIGPTHDDVTFAAVAQAFGEPLHPHPELARLVQGFFGVSEPGSAPMKLALVPASARLHYGADPATGRQLRFPLVSAHNVYIFPGVPSLLEAAFEGLRHLFASPGTRFHLRELFVDADEAALAPALARAQARFGRRVGLGSYPDWLSNYHRVRLTLDSDSAESVEEARRHLLDALPPGCVVPLVAEPVAVATQEVYRLAQSGTALGLKVASAVQTIETALEQYPPSQICVGFNGGKDCTALLHLYYAVLRRKFPQAEDRVKALYIRIVSPFPEMERFLKDTIKRYDLEVYMVEGNIRQALIDVQEQHPELQAVLMGTRRTDPYSRTLTPLCPTDPGWPHYMRVNPLLDWSYHDIWEFLRTLYVPYCILYDKGYTSLGSMDNTTRNPALQFVDERGVVRHRPAYQLENEEDERNSRK
The following text describes a protein:
Function:
May play a role in axonal development.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIAFPLQDYGGIMAGLGSDPWWKKTLYLTGGALLAAAAYLLHELLVIRKQQELDSKDAIILHQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYFGGKLSAQGKMPWIEYNNEKVSGTEFIIDFLEEKLGVNLNKNLGPHERAVSRAVTKMVEEHFYWTLAYCQWVDNLNETRKMLSLSGGGPFSNLLRWVVCHITKGIVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAMWTLPGTRPERLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPMLDFSFYSRTETFEDEGAENSFSRTPDTDFTGHSLFDSDVDMDDYTEHEQCK
The following text describes a protein:
Function:
RNA helicase.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MVRPLKRTRTRKTEKEPREPEPEPRFDDNEPIGEIESETDDSQAPIPSFDMGTDSTKPTAFDKLPWKKVRLPDFLGDGLSFDPDGGGLLGLEELDGSVWEDIKQSSRKRNLDQLEETDTQLKIEGQEISQQPASEVTPSQATIDKELRKKAKKERLAKLRQLKKDAQANKPDIPNTDSVNDSKNGPKRRESNQVEDELDDIDWAATADLDGMSDMERDVDNQLIMLPFDDSLLPAWLDLKLASPIKRALYNLSFTKPTAVQEASLPISLSSSDSPRDLVVIAETGSGKTLAYALPILNALILSPPSPMLKSSPQILPIVTLVLTPTRELCLQVKAHIDTFLKAMCSETQSSQEEGATNEPSSSKNRTGITTVSICGGIAIAKQRKQLERSKKLMEPGKGGLGCIVIATPGRLWDMIQSWDEFAEGIKRKLDWLIIDEADKMIEKGHFEELEKILKLTKRPKDRRPRHTTDNNNADEDDGEEEEWEDEWTSQANDADNYIKEKIRTMVFSATMDKNLQINLKKRSFKGKPPAVGGSIPPADPMHDLLEQIDFRDPHPELIDLTPQGRMVGGLKECKIECVLKDKDLYLLHFMLRYTGRTIVFLSSISALRRLSPMLNLLLPDSTVLTLHSEMQQRSRLKSLDRFRSSSNSILLSTDVAARGLDIPQVDHVIHYQVPRSSDCYVHRSGRTARAGKGGVALALIAPDELKTWRSLMKNLGRADDLPSPPIEHSISNKLKELLELAKKIDTLEHKSTKQSHDENWMKKTAEMLEIDLDHSNDESDGDDQDKQPKKGDNKAMTQAKILRARLKEKLADPLIIKNNSLIIRSKANHQHRPRKINNCFIKDPQVIKNFLSNQNHSHLVGLDRSVNALNELS
The following text describes a protein:
Function:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MALPVLDLELFRRRLKSFYNSWRETTPEVDATVISVGSDDNIIYAKSIAVQAWLLGCELRDVIIVLCHDRLYICAGRKKIEFLQPLQECTDENIKSVIYLTKHKGVDDNRDNFTELIDAIKKSKDGKNVGVIPKDRLTSDFTEAWKDVLDNDNELAKVDITPTIVQAMAPKDESEINLIKKAAHITSEVFSKHYIMQIMSIIDLEKKVSHYKLAESISNAIESEKYLAPNMDPQLVEVCYPPIIQSGGKQNLKFSITSNNELLKYDIITCFFGARYKLYCSNIVRTLLVEPTERQQQLYNLLLEVEEIILQELKEGVKLAEVYDKAKNYVVKRKPELESNFVKSVGFATGIEFRESVLSISPKCTVSVKKGMVFVVNVGFSDIAYENDKANTYGLFVGDTVIVNEDTSATVLTSAKKKIRNIGIFLKNEDEDSEEEDESDVMPRRSTTILESRTRSEETAEDRRKVHQAELKRKLNEEAKVLFVETPSVYDIKIFVKEKLSYKNQSLMPRDPDISNLKIYIDKKQESIILPIFGIATPFHISTIKNVSQSVEGDYCYLRINFFYPGSALGRFDGNVFSQPDATFLKELTFRSLNTKQSGSTTSPSMNLMTAFRLIKEVQKVYKTRETEQRERAGIVEQEALIVNPNRSNPRLKEVYLRPSVSQKRVLGTLEAHTNGFRYTSVKGEKIDILYANIKQAFFQPCDHEMVILLHFHLQNAVLMGKKKVTDIQVYTEIGEISADLSKYRHMHDRDDLMAEQTERERRHKLKVSYMGFTEKIENLTNKQVEFDTPIRELSFYGVPHRSTVLLQLSNFCLVHLIEQPVFIVFFREVELIHFERVQFHLKSFDMVIIFKDYSRKVATINSIPMSSLDKIKSWFDQYDIRYTEGIQNLNWTNIMKTINEDPEGFFENGGWNFLDMNDEDNGNESLDESEEDDVYEPSTDEDEDEDYEESMSSAVETDDEEDELCELDSDESEGKDWDELEAEAAKADREKQPEYDEDNNSRKRGMSKSSANNRPKKKSRH
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
LLAGHWSYLLVLTTLKETSSPSSLYHSLVNKNVTSKIVKWNKEKRPASNINISSAALLMMKNRIYPGDMVAATEHRTMQLLQAVLEPEASGEEEKVHLVLSMEDGHKLQQALQLVPPHRKIVLVHIHRPAMMIPVPTMGGTVHASILKDNIVKGYRDEQRDQALLALKGYKEICTRAEIQAETLMIENDNVSAGLLGLIAEHKITTLIIIGIGKSWVNRSKRNLAAALQRGADSSCNILFMHKGRLISDGSVFDFETKGTPSYISSRLLSSCSSNSSPSPYIWDSRSTPSSILWDSRSTPDSLDPSQLDDPSLEIASSIFGDSKLIVILGHESINTFRELTGHLNLVEYSHELHQAFQSKYSEITSRCQFIGGIDSVLGADSENCGEEYWKTIKAWPAAFEHIVRVLNTVLELFKQDSLKCNGLTPGEILISAKELINRFLDVALAVTEVRKSPEKLFCTLYMCRAIVDSTPSLKKLFPADFVSRVDSVHTVLNDSARGILREFKVLIQNYSSQKVAQDGGILLITGYVMKYIRLLINHAGSLDTILDYGQSSDLFFSKGNNDLLLFKGISLTGHLVCGLIGDLNNVIEQKSRLYASEGLRCLFLMNNANFIIQEVEHSDIQLIVGSEWLRQRRDDFDMYMRDYMSSTWERVTSYLTIASPPHKRIRPSLLGIIHTNTRHFQRFVSAVKETCNSQMNWRVPCPILRSKLRDNISEHINRAYKAYLEVLKQSSMAGFARDLKSEVSVSELFEG
The following text describes a protein:
Function:
Component of the type III secretion system 2 (SPI-2 T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (Probable). SseC/SctE2 and SseD/SctB2 are inserted into the host membrane where they form a pore and allow the translocation of effector proteins into the cytosol of target cells (Probable); Required for the translocation of SPI-2 effector proteins. Required for systemic Salmonella infection of the mouse. Essential for SpvB-induced actin depolymerization in the host cell cytoplasm.
Subcellular Localization:
Secreted. Cell surface. Host membrane; Multi-pass membrane protein. Note=Secreted via the type III secretion system 2 (SPI-2 T3SS). After secretion, localizes mainly on the surface of the bacterial cell.
Sequence:
MNRIHSNSDSAAGVTALTHHHLSNVSCVSSGSLGKRQHRVNSTFGDGNAACLLSGKISLQEASNALKQLLDAVPGNHKRPSLPDFLQTNPAVLSMMMTSLILNVFGNNAQSLCQQLERATEVQNALRNKQVKEYQEQIQKAIEQEDKARKAGIFGAIFDWITGIFETVIGALKVVEGFLSGNPAEMASGVAYMAAGCAGMVKAGAETAMMCGADHDTCQAIIDVTSKIQFGCEAVALALDVFQIGRAFMATRGLSGAAAKVLDSGFGEEVVERMVGAGEAEIEELAEKFGEEVSESFSKQFEPLEREMAMANEMAEEAAEFSRNVENNMTRSAGKSFTKEGVKAMAKEAAKEALEKCVQEGGKFLLKKFRNKVLFNMFKKILYALLRDCSFKGLQAIRCATEGASQMNTGMVNTEKAKIEKKIEQLITQQRFLDFIMQQTENQKKIEQKRLEELYKGSGAALRDVLDTIDHYSSVQARIAGYRA