lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis. Involved in miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Modulates cell cycle progression and global translation of pre-B cells, its activation seems to be rate-limiting in tumorigenesis and tumor growth.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between cytoplasm and nucleus/nucleolus.
Sequence:
MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSETIPVVHASIAGCRIIGRMCVGNRHGLLVPNNTTDQELQHIRNSLPDSVQIRRVEERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSAIATSMRDSLIDSLT
The following text describes a protein:
Function:
May act as a carbohydrate transporter. Required, together with ENODL11, ENODL12, ENODL13, ENODL14 and ENODL15, for male-female communication and pollen tube reception and burst at the synergid cell surface of the female gametophyte.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MASSSLLVTIFLCISVFFFSSVNANEVTVGGKSGDWKIPPSSSFSFNEWAQKARFKVGDFIVFKYEAGKDSVLQVTREAYEKCNTTSPKASYTDGNTKVKLDQAGPVYFVSGTEGHCQKGQKLRLVVITPRNSAFSPGPSPSEFDGPAVAPTSGAAKLAGGFSVVFGLVLGLWAFFF
The following text describes a protein:
Function:
RNA-binding protein that regulates tissue-specific alternative splicing events by binding to 5'-UGCAUG-3' and 5'-GCACG-3' elements. Also binds to poly(A), poly(G), poly(C), or poly(U) stretches of RNA. Plays a role in the sex determination pathway and X chromosome dosage compensation, and together with sex-1 is involved in making the distinction between one and two X-chromosomes. Binds to 5'-GCAUG-3' and 5'-GCACG-3' elements in intron 6 of the pre-mRNA of the sex-determining factor xol-1 to promote its alternative splicing and together with sex-1 negatively regulates the expression of xol-1 to promote hermaphrodite development. Negatively regulates the expression of the active isoform of xol-1 (isoform b) by promoting intron 6 retention and the deletion of exon 7 coding sequences in hermaphrodite embryos. Furthermore, binding to the pre-mRNA of xol-1 can also direct the use of an alternative 3' splice site enabling the xol-1 transcript to be trans-spliced to unrelated genes on chromosome 2, which also leads to xol-1 exon 7 deletion. Does not seem to regulate the retention of introns 1 to 5 of xol-1 pre-mRNA. Plays a role in the association of the dosage compensation complex proteins dpy-27 and sdc-3 with the hermaphrodite X chromosomes. Binds to 5'-UGCAUG-3' elements in intron 7 of the pre-mRNA of unc-32 to promote its alternative splicing in neuronal tissues. Binds to 5'-UGCAUG-3' elements in intron 4 of the pre-mRNA of egl-15 to promote its alternative splicing in body wall muscle tissues. Promotes binding of RNA-binding protein sup-12 to target RNA. Plays a role in male mating behavior.
Subcellular Localization:
Nucleus.
Sequence:
MAELIEEVSTATHASLNACDPIVVNSEALPMQALYQLSATGAQQQNQQIPIGLSNSLLYQQLAAHQQIAAQQHQQQLAVSAAHQTQNNIMLATSAPSLINHMENSTDGKVKDDPNSDYDLQLSIQQQLAAAAQAAQMGQTQIGPQIVGQQGQPVVATTAGSTNGSAAVTQPDPSTSSGPDGPKRLHVSNIPFRFRDPDLKTMFEKFGVVSDVEIIFNERGSKGFGFVTMERPQDAERARQELHGSMIEGRKIEVNCATARVHSKKVKPTGGILDQMNPLMAQSALAAQAQMNRALLLRSPLVAQSLLGRGAALIPGMQQPAFQLQAALAGNPLAQLQGQPLLFNAAALQTNALQQSAFGMDPAAVQAALLANEQARFQLAAAAAQGRIPSSGNASAFGEQYLSNALATASLPSYQMNPALRTLNRFTPY
The following text describes a protein:
Function:
Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MKNKKQNTTYFDIFGKVQTEVGVQEDSNTTEISPMQVRNFALSIFNVVSIPKWAKIEHSSLAKRVIFLYFNGIDLNRYNKYFDEISNFHSMKENGFPVTVLASLKGNRIVPPEQSLLGYAINPKELKCFSSFDEMLLSDHKLLDNGFPLPEDPNREDFQGKHRFEEFGIKPLTPEELSRFKCLPDHVDNANKVIALDCEMIETTSEDGAKHDELARLSVVNEKGEVIIDEYFKPIHPVSDLRTHVSGITQEHLDNAKLTSEDGVSALSAVADKETIIVGHGLENDFKALLLFHTKVVDTSLIYNNERGVTYPRKPKLSNLFQKYFKKEMRDQTKPHDSIDDARAALELSKFCLNHAVSNVPIPPKIPDMFSSLLKAVTSIDVLAHERMINFKDLDPRVHCILEDEDEPRKQKLMESVKNDSSEFVFAYFNGMSRCEVNEEEERKAAKFYNDVLGDVLSVMPKSSVLIVYSGGGSTRRISELKDIPAKNAEMNLCKQGLLWAKATPPEE
The following text describes a protein:
Function:
Inhibitor that slows proliferation of secreting cells (also known as chalone). May function by binding to cell surface receptors. Requires cfaD for activity. Overexpression slows proliferation.
Subcellular Localization:
Secreted.
Sequence:
MSKLLILLLLSLVASIFSTPLDDYVNAPDDTYKWTLNNTIEYETFTGYILELTSQTWMAEKSDWPVWKHWVSICVPKGVTTTTTFIYVDGGSNDNWKVPGSMDQTIEIVCLSSGSVSVGLTQIPNQPIIFNNDGVQRFEDDLVAYTWRQFLGNTSEPLWLARLPMTKAVVKCMDAVQEFGKTIGYNSENFVIAGASKRGWTTWLAGVVDPRIIAIVPIVMPILNMIPNMGHQFYAYGEWSFALNDYTGQGVMDYLNGPQMVELAAIVDPFSYRDRYTMPIYAIASSDDEFFLPDSPQFFWNNLTATPEKHLRIVPNAEHSLMGHQIDIILSIVTFVRLLITNQPRPTFTWDITYSEDLNSGTIVLTVPEGGIIPYKVKVWTAVTESTTRRDFRIITCMDITKCIQFIIWDPSDITPTSTGVYSITLSKPDAGWRAFFLEAEYLYAKNSIDDEYTLKFTSEVAIVPNTLPFGSCSEYNACGDGSQGDSASSTATL
The following text describes a protein:
Function:
Stimulates the secretion of gonadotropins.
Subcellular Localization:
Secreted.
Sequence:
MDLSNRTVVQVVVLALVAQVTLSQHWSYGWLPGGKRSVGELEATIKMMDTGGVVALPEETSAHVSERLRPYDVILKKWMPHK
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC30.
Sequence:
MALSIKHPEADRLARALAARTGETLTEAVVTALRERLARETGRARVVPLRDELAAIRHRCAALPVVDNRSAEAILGYDERGLPA
The following text describes a protein:
Function:
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. May be required for rapid internodal elongation in deepwater rice during submergence.
Subcellular Localization:
Membrane; Peripheral membrane protein. Secreted, cell wall.
Sequence:
MASSRAAAGPFALCILLLASPAVSATFLFDGGKSAAKSKGKGKEAVDVEWRPATATWYGEAEGDGSTGGACGYGTLVDVVPMKARVGSVSPVLFKGGEGCGACYKVRCLDHGICSRRAVTVIVTDECPGGGLCGGGNTHFDLSGAAFSRMAVAGAGAHLRDRGQLKVIYRRTACKYGGKNIAFHVNEGSTSFWLSLLVEFEDGEGDIGSMQLKQANSAKWLDMKHVWGATWCLYGGPTAGPFSVRLTTLSAPKTLTARDVIPRNWAPKGTYSSRLNFDASL
The following text describes a protein:
Function:
Hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane. May also cleave GPI anchor intermediates intracellularly.
Subcellular Localization:
Secreted.
Sequence:
MKNKIILLWLLLIVILCTISNVKGCGMTTHNTVARRAYNFSSFDGFEQYQKYVSENFDVFDAGAAFPDFGYDCGGLANESEAAHWPPFLRAATKYLLETYPQPWSLDGIRLAVFLLGVTSHQIADISWHSIGGIQQGLIRAMAGQDFNGTYELAHGNADEGGEFELAYNYDLSWLSDKWYVPITDIKNIFHSMNYPRVDDENLLRCNAILYAGAMGVKIGGRFFYPEIAKKSPFLVDHYQDYFIGGLDDMSIWTSYCWPVLMGWMDGEDIGDFCFIQPDPNNDDDNQHLRLHHKHSILKNGSKIKEALSKSILNEMKITNNGKGVTFSLPNSMEKAINQVLNKFNQNPIGTLLEKYLPNLFNNKNKFYQENENEQYNHDEEELNIIDIDIDIEEEEQEEEEDKPIRMLSKNNNFKNYEYLNDKKKSSSSKLKNKSKKNIIKLNSDSNDLGTNFTTIYGQNMYSYFGKDIRSKDLNGDGFDDLIISSPGFGVPGSMQTGCVYYIISNGSSVTIDGGSGFTSEFDIDQVATGKLCGNETHAKFGWNIDVLDFNLDGIFDIIIGAPSSSNANLQYLGMIYIYLGEKNNPAGEWSTESDLPSITIQGIEYADTIGTVLRVADCNADSNADLILGSPHSAGGGTQRGTVQIFYSSKKRISGIPISLNDADYYGHGEVDYEWFGYEIKVAGQGDSSTLLVGSPNYHDEETAIVNIGKITSFPYNVNLNSFDLNPKFVMVGVNKNDKLGYSYNMVNGSLFGLDNVNDIMVLSLPTRGFGDDFDQVGEVVLIDIDNLSGFVEIKNVNLLLSIKGTTKYSRFGESLLIGKLESTDEFARLFVGAPLWTDSIDTGPGCVFTFLPNQHLTNDPAVLKQNIINNTPVVIYDSTHSIKTFRIDDDSGSSGGRSFNNKRKDSRFGFRILLSDFNNDGKNDLIVSADRDSSKILEGGSINIFQ
The following text describes a protein:
Function:
Non-catalytic subunit of the NovJ(2)K(2) heterotetramer that catalyzes the NADPH-dependent reduction of the tyrosyl moiety of L-beta-OH-Tyr-S-NovH intermediate to yield the tethered beta-ketotyrosyl-S-NovH in the novobiocin biosynthesis pathway. Novobiocin is an aminocoumarin family antibiotic that targets bacterial DNA gyrases.
Sequence:
MTRVAVVAGGGEHTGPAVALRLAAGGFDVALLGSEFTSADKTVRRVEEYGRQCVTVRAELSDARSVAVAFGRVRTALSGPAVLVTCVGPQPLPDGLPEDESADEQRYTAVRRALRPVFVCCQAGAGQLLRHRWGRIIIVTEPADADGNTWRTSRPVLDGLIGFTRSAALELARSGTTVNLVAPADRAADSRAPAHRAAGDDSAGSYADGVAHVTEFLVDERAVGITGQAIRVAARADVPLLRER
The following text describes a protein:
Function:
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays no strong substrate specificity with respect to the carboxylic acid moiety of Acyl-CoAs. Hydrolyzes medium length (C2 to C20) straight-chain, saturated and unsaturated acyl-CoAS but is inactive towards substrates with longer aliphatic chains. Moreover, it catalyzes the hydrolysis of CoA esters of bile acids, such as choloyl-CoA and chenodeoxycholoyl-CoA and competes with bile acid CoA:amino acid N-acyltransferase (BAAT). Is also able to hydrolyze CoA esters of dicarboxylic acids. It is involved in the metabolic regulation of peroxisome proliferation.
Subcellular Localization:
Peroxisome matrix.
Sequence:
MHLLDELEELDVDLFRATTSWQPPFTQRIYGGQVIGQALVAASKTVDEQFSPHSLHSYFLRHGDPSIPVIYKVERTRNGRSYCSRNVYAIQRGLTIYTSQISFSKFEKSVIEHQNDMPNAPDPESLPTTKERLQGYLERGVRGDRNRSAIEKAIASEIPLDIRPCDRKRIGFFDPDFESKAPYQLVWIKTVDKIGPGFEKLHQCIAGYASDYSLLQTARLPHPKFRVNFASSLDHSMWFHLPFRADEWMLYELESPKANNGRALVFGKLFTQDGRLAVTVAQEGVLRGVIKDHPSRL
The following text describes a protein:
Function:
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
Subcellular Localization:
Cytoplasm.
Sequence:
MPAFETVVIAYRAEEAHSRIAADRCESLLHKVGCRVLKGPTGPQDNPYPHFLEATGGHIDLAIVLGGDGSILAAARYLAAVDVPILAVNVGGHLGFLTQPPEVLGGRYWERLLAGEWELEKRMMLQASLTGPPPLPERQPYFCLNEFCLKPASEMRLTSIILELAIDGEIIDQIHGDGLLVSTPTGSTSYTVAANGPIIAPSLQAITITPICPLSLSSRPVVLPATGTIEVSPLRDPDLNIKLWSDGAFAAPVHPCQTVRIEVARHPTRLLILEEDHSYFRTLREKLKWAGTRIQAERDPECLLPPQNHP
The following text describes a protein:
Function:
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P), and hydrolysis of thiamine pyrophosphate (TPP) to thiamine monophosphate (TMP). Can hydrolyze other substrates such as MeO-HMP-PP, CF(3)-HMP-PP and MeO-TPP. Is also a non-specific nucleoside tri- and diphosphatase that releases inorganic orthophosphate.
Sequence:
MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI
The following text describes a protein:
Function:
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex.
Subcellular Localization:
Chromosome, telomere. Nucleus inner membrane. Note=Localizes to telomeres during meiotic prophase. In leptotene spermatocytes, localizes to telomeres that localize to the nucleus inner membrane.
Sequence:
MEATKTDLRLLLECLKYQMKWPGSQKQALLTIISICKQNDQYVEFLREIGGISFIYNLSKSSTFSQVKETALFTLASLAELHESCKQALCREEMFRDFVQHLEQEMPLTEKRVAVYMLSVLVANNRCGQTLAKTSRCIEALLRLFRQSFPVPGESYEQLQLWITVSSALCGSVNNPQNEENQNVCMSVFPEIKPWLQEVALPRAELAQPLCSFIGMTVANNPCAQEYFVSVGGLDSLSDTLTRVLSQSTHSASVCKMATIITKTLSACISNNELLGSSLSKLRVIPGLLRLLSSPNLDPQDQLAVVLTTGHLTDACVEQQSQLLSAGGLPIIITLLTETSDEELKKAAIFVLHTCNRITESLGPGMSTIDPNECDREGQWRSAGQILQRIQLLEKKIGKKLWERDPESQPHSMKRSDSHVECDDELWEGSVMRKVKGNHRVYGEFRAIPAGTPITSEILQDQDSLQPDSSEEGLSPVQVNLFKGPNWEKSKKRKHKQKRENERSDNQETRREGVNKRELKRNVKSERVVKRLKMMNLESDDDGYELLQNCSTPTEGNRDTQGPDIFRHPDPVKRNQREPSLSDDNMSLCTELLDKEINKFLKPPSASKSNTLRCAGCVKHMNELNSRSFGAVLSSCRFQCDFHLTLREAEDRFRRSQPLKRTSHTPTHTHINTHRKIREHSTSAQEHKQKSKREKHKLSHQSSDRCYRLTPLRRPRETYSPDVKQWTDHRHLKKSSEDARSKNSSGRHRKRQNWSDKELCYLTKGVKRFGHSWNTILWKYPFHPGRTNVDLAKKFYHMQKAKAQGVDLSVAKAL
The following text describes a protein:
Function:
Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU (ISU1, ISU2 or ISU3). In a second step, the cluster is released from ISCU, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISCU depends on the function of the cysteine desulfurase complex NFS1-ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MTCLLSPFLFVPIARLDTITRRKPKPNGTRGESRDASYDSELRALPAAMMLRAAGRRLLGLGGGEAAPPVPPVATVAAVAIRGRGYHERVVDHYNNPRNVGSFDKDDADVGTGIVGAPACGDVMKLQIRVDEGSGRIVDARFKTFGCGSAIASSSVASEWIKGKQMEEVVAIKNTEIAKHLSLPPVKLHCSMLAEDAIKAAVKDYEAKKGKLAKAEEQDIPSP
The following text describes a protein:
Function:
Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP.
Sequence:
MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKELNYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIATGKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPLVDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNRIYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDSVNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK
The following text describes a protein:
Function:
Controls actin polymerization and depolymerization.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MNSCASINDEVITKYNELILGHISKGIIIKFSDDFKEVVFEDSFNGESFEDYINKFPQDDCRYGVYDFSYMDNKENKKNKIFFISWCPVETKIKNKIVHTATEQSIYKKLVGIDAIIKATDNTEISQSLVEERCK
The following text describes a protein:
Function:
Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure.
Subcellular Localization:
Vacuole.
Sequence:
MSDIQDISIISTKEVDTPKPHTVYIIQVTTPTRTWAVSRRYNDFVALDAELKSSTGQEPPSPLPPKTWGLSLGKNNRDRARERKPLLEQYLRSILNTKSHLWRSAYTFSDFLSIPSHTGSSSTQKSGTKFTPQSWLLEHAALQTVLRSARSALLKRDALASMSNATGSRSAGVEAKRHLKEVGNRLEALEKGLSQLRDIGQGELRRREELVEGLKVEAGSLTRMAEAGVRTAPSLSDNGTTGGSGTAGRRGEASPWTLPAQSMPGALPSGRVFGGHQPPQETEQTRPLDDRQLLQLQTNHMAQQDDQLQNLSRVLQTQRRMGEEIHQEIESQNELLEHIEQGVDKTGRKLGKAKREMNRLN
The following text describes a protein:
Function:
Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
Subcellular Localization:
Cytoplasm.
Domain:
Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
Sequence:
MTNPLRVLVVDDSALMRRLLRQMLESDPTIRVVGEAGDGKTAIALTAELRPDVITLDVRMPVLDGVETTRQIMAYHPTPILVLSAAVSGQDANISFEALAAGALEVMEKPSLTDPDSLDHLRRVLIRRVKLIARIKVVTHLRGRRQPPPVERVSLGDTPHYVRTPRIAPGQFPVLVIGASTGGPKVVRQLLAGLPRTFGAAVIVVQHIAQGFGAGMAEWLAGASALPLELASEGMLLRPGHAILAPDRADLLIKPDGTVHLSMSPLLLQRPSIDITMTAVAELYGASAAGVLLTGMGRDGAVGMRAIRRAGGLTIAQDEASCTIFGMPRAAIELGAAELVLSPEEMIVVLSERFAGSASMP
The following text describes a protein:
Function:
Neurotoxin that produces dose-dependent hypolocomotion and hyperalgesia in mice. May directly act on the central nervous system, as it is 6500-fold more potent when administered intracerebroventricularly than intraperitoneal.
Sequence:
MEDEDGYMAIESGRRDLYMQPSPKEAQGDSSSNCCKITTIVSLIGSLALNVALIILIIVFQVRNAPTSSCPLPLPNSCEWIPGSSTERVLLDPRTAHRRIIISPDQRSAKWGPVEQPLPNNTERFDQRVWVLGNKGYPSGKHCWEVEVKGNGEWAVGVAKESVKRKGLPDFSTTEGIWGIGEYWGLGNYLAFTAPQHTPLPLVKKPRMIRVFLDHGQGSVEFFDAEAKASIYTFTSAPFSGETILPWFRVWNGTELVLHP
The following text describes a protein:
Function:
Involved in the regulation of glucose homeostasis and lipid metabolism.
Subcellular Localization:
Secreted.
Sequence:
MGAALSQGALIAIICNGLVGFLLLLLWVILCWACHSRSANIDSLSESSPNSSPGPCPEKAPPPQKPSHEGSYLLQP
The following text describes a protein:
Function:
Transcription activator of STM and KNAT6. Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation. Required for the fusion of septa of gynoecia along the length of the ovaries. Activates the shoot formation in callus in a STM-dependent manner. Seems to act as an inhibitor of cell division.
Miscellaneous:
MISCELLANEOUS: Overexpressing transgenic plants exhibit adventitious shoot apical meristems.
Subcellular Localization:
Nucleus.
Domain:
The NAC domain includes a DNA-binding domain and a dimerization domain, and confers the specificity of the transactivated target genes.
Sequence:
MDVDVFNGWGRPRFEDESLMPPGFRFHPTDEELITYYLLKKVLDSNFSCAAISQVDLNKSEPWELPEKAKMGEKEWYFFTLRDRKYPTGLRTNRATEAGYWKATGKDREIKSSKTKSLLGMKKTLVFYKGRAPKGEKSCWVMHEYRLDGKFSYHYISSSAKDEWVLCKVCLKSGVVSRETNLISSSSSSAVTGEFSSAGSAIAPIINTFATEHVSCFSNNSAAHTDASFHTFLPAPPPSLPPRQPRHVGDGVAFGQFLDLGSSGQIDFDAAAAAFFPNLPSLPPTVLPPPPSFAMYGGGSPAVSVWPFTL
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Independently of its E3 ubiquitin-protein ligase activity, acts as an inhibitor of CPSF3 endonuclease activity by blocking CPSF3 active site.
Sequence:
MAASAAETRVFLEVRGQLQSALLILGEPKEGGMPMNISIMPSSLQMKTPEGCTEIQLPAEVRLVPSSCRGLQFVVGDGLHLRLQAQAKLGTKLISMFNQSSQAQEYCTFYCQSCGEVIIKDRKLLRVLPLPSENWGALVGEWCCHPDPFADKSLHPQENDCFIGDSFFLVNLRTSLWQQRPELSPVEMCCVSSDNHCKLEPKANTKVICKRCKVMLGETVSSETTKFYMTEIIIQSSERSFPIIPRSWFVQSVIAQCLVQLSSARSTFRFTIQGQDDKVYILLWLLNSDSLVIESLRNSKYIKKFPLLEDTLKADSSSAWSAVKVLYQPCIKSRNEKLVSSWERDISVHPLTLPSATCLELLLILSKSNANLPSSLRHMNSFQVAFLKM
The following text describes a protein:
Function:
Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MDACKMPQRFHLRNRNESPRIPRTVPNGKGVLLEDKTSAMLKNFSICDQVKLFVADHDSNIIENSHDGSENVYHKQITGSELNGGELKGDLATINNPSNSLLPSAKEIHSVNIISASTMIPSKQNTLKSIPDNALSGNCDLKFNPLFEPKCHFCGLFGFLRCTQCKQVYYCSVACQKKDWQKHSVVCKKVQLNTDKAEDNPKPSIEIKNKENVVSVKTNKTVEQCKKTMISDLGMLELRKNMKVEGTVTEFLNPHEFYIQIKTVEVQTNIRKLSKELKNQVGINLNEYFPIKGEVGIAQSSLDQNWYRVLIKEVDILKKNGHVLYIDYGNEDNIPLNKIKQLPKDIAQLPPCAAKCSVENALFVKEKWNAVSRNTVAPRLKGMRCFLTITNILRGEIPCFIVDVTLPDSGKHLHDMLLEIENVLNLKNVHIEMGNSTTGSANKSNIQENKCESKDHSDCLTPKVISLSIGDSFWGLVSHIQTPGDFFCQQIKNGSKLSKLQVSLNEHCEKISTMKDFSPAIGEMCCAQFTEDQQWYRALVLSFVSENTVLVDYVDYGNVEVLDLCKLRPIVPELMELPAQAIRCTLSGVKPVSETWSTEATSVMKKLFHNKVVIIKVLTMKENNFVVEITDDSMTPIINVSSYLLKSGYAVEESPAAVVTESRTTTSEEMSGQKLDQLDASWVTLTAKQVADVIVCVLFNPSEFYCQVYCHKDLVALEELNLSLMEYCEKAAPCVSKITKGELCCAYYSADGRWYRALVKDDASIEVQFVDYGNCEKVTLDKMRPISATFMKLPFQAIRCCLSGVCPINKEWSNEATAALQKWIVGKKLQAKVVSSIKNSAEIELTDNTTGSPILINDILVNEHLAFKKELMLNKKMPSVELAHDFQEMSLNVEWTTVKFAVGETVSVRVLDVINPELFYVMPTKPKVDLQELHKLMTELADFCSFQNGHPLKPKVGEPCCARFSGDNKWYRALVLRILVSEVKVVNADYGNVEMLPFSRLLPITSTFLELPFQILKCSLAGITAPATEKIKSLLFNECVIITVKGVNKNIHEVTIQKNCENRTLETADEMVIENSVCCISGNQCAEKDKFCFTDWKKRVVKLEKIVNFLLKDRFGEDEPPEIAKFLEQ
The following text describes a protein:
Function:
May act as receptor for class I MHC antigens.
Sequence:
MALVLILQLLTLWPLCHTDITPSVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGSYRCCYRRPDWGPGVWSQPSDALELLVTEELPRPSLVALPGPVVAPGANVSLRCAGRLRNMSFALYREGVAAPLQYRHSAQPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEGEGPEARPASSAPGMQAPGPPPSDPGAQAPSLSSFRPRGLVLQPLLPQTQDSWDPAPPPSDAGLQAPSPSFLIQESRPQPLLPGPRS
The following text describes a protein:
Function:
Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
Subcellular Localization:
Nucleus.
Sequence:
MVEETLVNNNSSLYGDDDEDSFFREIKEISRGRPKTRDEISINDRSRLSRWDSTPSMDSSPFSSIFKTLPPGLTDEQISALILRLRIDEITKKVTIGPIEITDRDRDRSPSPPPIYDSNGKRSNTREQRIKDKLQKERHHLIVTAQRISPTYKPPSDYQPPNEKKIRKIYIPIKDHPEYNFIGLIIGPRGNTQKRMEKESGAKIAIRGKGSSRDGKSTKIQFQENDELHVLLTADTTDQLDKAEVLVREFLVPVEEGKNEHKRQQLRELAEMNGTLRERPAYMGNRSWTPVDIKCSHCGETTHPSSDCPLRTNESNQQYIETEYQKFIDEMSNALGFDINQSNVEPPPQQQNNNGYDQGHYNRNSNENLGDMDESPPHHQQQYQGSNQPPYQQQWSNNNNGYNNNYSNNSQQQQQPFYNNQNSSPYGPPRNY