lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for normal spindle orientation at male meiosis II and normal formation of tetrad of microspores. Not involved in female meiosis.
Miscellaneous:
MISCELLANEOUS: Diploid male spores in sp1 mutants give rise to viable diploid pollen grains and spontaneous triploid plants in the next generation.
Sequence:
MEVKEEKLMEEKQRLPEKTIPVFTVLKNGAILKNIFVVNSRDFSSPERNGSTVSDDDGEVEEILVVGRHPDCDILLTHPSISRFHLEIRSISSRQKLFVTDLSSVHGTWVRDLRIEPHGCVEVEEGDTIRIGGSTRIYRLHWIPLSRAYDLDNPFVSPLDASTVLEQEEENRMLEAENLEVAQHQSLENTTSGDEGVLHLDVTSEGTGSSVPSEDEDTYVTTREMSMPVASPSVLTLVRDSVETQKLQFNEDLQTSPKWDLDVIESVAEKLSGSFVRSTQQSGGDVEGLGCSELFDAAEADECDVRGDGGLHLNVISEKMESSVPNMIEAENLEVAQHQSLANTALGDDEDLHLDVTSEGTGSSVPSEDEDTYITTMEISVPLASPNVLTLARDSIKTQKLQSTQDFQTPTMWDLDVVEAAAEKPSSSCVLGKKLSGGYVEELGCFELFVAAEADKCDVRGDGSLHLNEISERMESSMSNKEDDPFLAAKETSSLPLSTDFINPETLWLVEDVQASPEFCTSSVKANAENPSSGCSPSTEQIDGCFETSGCSAFDLAAEVESLSLHQEVSEETEFVTKEVMGVSSEPLGKADIRSHEENGESEDSRQVIEVSAEPVAKADIQSHEENGETEGSRQVIEVSPKSFSEAEPTIEILTGEAQGIIGSEFPSELAVETESENLLHQKSIGETKNEIRSHEDYGETEDYGETECSWPDIAVSPSSVSPPEPTLEILTDEARGLLGSEFLSEVTVETEIENLLHQKSNVETKADILIHEDYGETEVSRQIITVSPNSFSKAEPTLETEDSRQQARGLVGSDSEFQSEVAMKTECENLLNQKRNGETKVSSRQASPVSDCLSTPKDRLSSINTDDIQSLCSSSQPPSESEVNPATDQDQESGIISETEKPKTELLIGSGRSEKYYSLSEIEGEENTDIGRLSRCPIPSALAAKTSEDTKLIEELSSSDSGSQENQTPETHAVRDDVLCDMDSSSTCNIWSRRGKAASVLKIRTNKSQGKQKQTGRQPKDKLHRKQALSDKSISLTIHHGAEILEPEIFTPDKENLTPSSHMLKRLQDIGDVKDSKSSLKLSGKSCSSLVHSSIAVLASEAFTEPEIFTPDKENLTPSSHMLKRLREFGDIKDTKGSSSKATRKPFFDIRMEENVMVEQEPEDLHSLGSKSKLKHEPLAPKKKAERAPFQPLLEKSSFQSQSYTEASSTASARNNISRGIRSSSNLSDAKSKMKWTIVLDTSSLLDKESRKPLQLLQGLKGTHLVVPRTVLRELNEVKRSRSFLFRRRTEIASSALDWIEECKVNSKWWIQVQSPTEETKAIAPTPPVTPQSNGSSAFPFSLHWNNYAPEIDSPTSEDQVLECALLYRNRNRDEKLVLLSNDVTLKIKAMAEGVICETPHEFYESLVNPFSERFMWTESTARGRTWSHLDNDVLRERYNDRACRRKSTYNRGESGAAAKGLKLILLHNSHYGHTH
The following text describes a protein:
Function:
Protein O-mannosyltransferase that catalyzes the transfer of a single mannose residue from a polyprenol phospho-mannosyl lipidic donor to the hydroxyl group of selected serine and threonine residues in acceptor proteins. Sec-translocation of the acceptor proteins is required for protein mannosylation, suggesting that O-mannosylation should affect only extracytoplasmic proteins. Is crucial for virulence. It may play a role in adaptive regulation of the mannoproteome during host cell infection; Overexpression in M.smegmatis decreases the cell envelope permeability and promotes microbial biofilm formation. It also inhibits the release of pro-inflammatory cytokines in serum and significantly promotes M.smegmatis survival in the lungs, spleens, livers and kidneys of infected mice. Overexpression in M.bovis strain BCG, the only effective tuberculosis vaccine in common use, leads to a strain that secretes more glycosylated proteins, significantly enhancing macrophage activation and immune protection against M.tuberculosis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTARPPESCVLAKDRPEEPVVPVVSPGPLVPVADFGPLDRLRGWIVTGLITLLATVTRFLNLGSLTDAGTPIFDEKHYAPQAWQVLNNHGVEDNPGYGLVVHPPVGKQLIAIGEAIFGYNGFGWRFTGALLGVVLVALVVRIVRRISRSTLVGAIAGVLLICDGVSFVTARTALLDGFLTFFVVAAFGALIVDRDQVRERMHIALLAGRSAATVWGPRVGVRWWRFGAGVLLGLACATKWSGVYFVLFFGAMALAFDVAARRQYQVQRPWLGTVRRDVLPSGYALGLIPFAVYLATYAPWFASETAIDRHAVGQAVGRNSVVPLPDAVRSLWHYTAKAFHFHAGLTNSAGNYHPWESKPWTWPMSLRPVLYAIDQQDVAGCGAQSCVKAEMLVGTPAMWWLAVPVLAYAGWRMFVRRDWRYAVVLVGYCAGWLPWFADIDRQMYFFYAATMAPFLVMGISLVLGDILYHPGQGSERRTLGLIVVCCYVALVVTNFAWLYPVLTGLPISQQTWNLEIWLPSWR
The following text describes a protein:
Function:
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
Subcellular Localization:
Cytoplasm. Mitochondrion intermembrane space.
Domain:
The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation; The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters; The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.
Sequence:
MTSSINILLLLHPTVVTDAQLVEQIKSKIYQSHNNNNNNNGGTTTTTTGTVNINLNQQIIDRVTKGIIELPYDYYDEIIYINPNNESQYREIPISLMQLIYKLLKSNGKFKGDLPLDQNLDVLMTGFIIEEEEKEKEKEENNLEGELVNVWVKPIPVDEPVVTLLKKKTTTSNTTTIKKSLPLFKKLNKDEINNSDKDINNDNITNNNNNNNNKRKLVETKLTYFSSDDENSSDGSVLENDDIDDDDELIDENDLLNFNNNNNTNGGSLLSDKLITPRKCDISLNGGKKRKKACKDCTCGLKELEELEVSNQQNLQDQILGKLAQSATLEAIKIEERLKQQQQQQQQKVKVKFTEEDLSEIDFTVQGKTGGCGSCALGDAFRCDGCPYLGLPPFKPGEVVKLDGFGEDI
The following text describes a protein:
Function:
Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity).
Subcellular Localization:
Cytoplasm. Cell membrane. Note=Associates with membranes through the PH domain.
Domain:
The PH domain mediates binding to phosphatidylinositol 4,5-bisphosphate.
Sequence:
MDLMNGQASSVNIAATASEKSSSSESLSDKGSELKKSFDAVVFDVLKVTPEEYAGQITLMDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSKEDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASREDLVGPEVGASPQSGRKSVAAEGALLPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNTAEFKSATFPNAGPRHLLDDSVMEPHAPSRGQAESSTLSSGISIGSSDGSELSEETSWPAFERNRLYHSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MTAQVEESNNPRRESDRAGRMSDVVSVRKAMYLDCIRNHAVALGQVGHCLDGCTEFVQPLGSRLNCEGCGCHRSFHRRVMFDVSISVSVSPTPQPQPPQRQPVPTAVLSGDSSATESDEDDFQRSVPAPQQQRRAPVAVAQQQQQQHYPAPLPMMVVAPEQVKRPRASFTTEQKTKMEELSERIGWFYKQRNRATIEEGCREIGVTSSAFKNWMNNTKTKRNKLRRASVSANNNNAAPPAAASCSPALPPPPPAST
The following text describes a protein:
Function:
Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MIPPGDCMYAGRKRRKPIQKQKPSSANEKTNPSKRHRDRLNAELDRLASLLPFPPDVISKLDKLSVLRLAVSYLRVKSFFQASQEKTSRKQMIGSASSNPNPRKESVSLDATISESNLLLESLTGFALVVSSDGMVFYASSTIVDYLGFHQTDVMHQNVFDYIHIDDRQEFRRQLHWAMCPPQHQGAPAQENQQASGAGEDFVVSSLFNSPEAGEIPPELSCFLNRCFLARVRCLLDSTSGFLTMQFQGRLKFLHGQKKKTASGVLVPPQLALFCIAVPLLLPPISEMKVKNILMRGKNKGGGVISAMDQSPHSDRGEHLRRHSLNGGMGDISDPVLLSCPNMGASQRGHHASWNAVCKDNHKYHPDGYLNQEEPLNYCKSSMAAHKGLHAGMGGGWPLQQNSGPLRGAQGCIPTNRLNRASQYGRPYRYSPSCHNGRSNEVFISKLYENVQLPTDPDAFCVDLVKSEGDYAECYDQHLMPAMQPIKVEQDSDSENGCDVYGQTWATRDQVPIDRRYGNGFYDPNSGLQLKSEADYYDQQYSPCQRGKVGISPPYNHSNYPNYAVNNGGGTAARLLKSDKDLSDSSHFSPQRLSHSDSLCNNQSVNHMDPHIYPQNPNKSYMHPDYNKHGTYEFKGHGRIHSIKREPMDSPPWSDSGPDINHSIMVGARNVMPCVMSTGHQRSSPYMYMP
The following text describes a protein:
Function:
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
Subcellular Localization:
Cytoplasm.
Sequence:
MGSKTPEGHGQGPDGSSSNTAINCSNPPKSAAASGLVHVALEGQGEDSDDDDEQIRLHLNGSGANGTKKKRKRTKKKSKKASETKQSIPPRIALDDIFNGRPYPEGEITEYTTKDDNLQRTTAEEIRHLSAVANMDDDFLHDYRKAAEVHRQVRQHIQIIAKPGISLSTLALEIDNAVRSLTGHPGLEKGDALKAGIAFPTGLCLNNIGAHWTPNAGGKEVYFQENDVLKIDFGVHVSGRIVDSAFTIAPNPIYDPLLAAVRAATNTGLRLAGPDARISHISAEMEEVMESYEVDIHGKTVPVKAVRNITGHNILRYKIHGDKHVPFIASKTSQRMEEGDIFAIETFGSTGKAVLRDGSGVYGYGRKEGGSVAGVHHASAKSLLRTIDENFGTLVFARRQLERLPGVEKWHLGMKTLVQAGVVESYAPLVDVEGSYVAQFEHVSFEIGMMR
The following text describes a protein:
Function:
Phosphatase that dephosphorylates some steroids such as ecdysone 22-phosphate (E22P), 3-epi-ecdysone 22-phosphate (E22P) and 3-epi-ecdysone 2-phosphate (E2P) in vitro. Also displays acid phosphatase activity towards 4-nitrophenyl phosphate (pNNP) in vitro. Has no activity towards 3-epi-ecdysone 3-phosphate (E3P) in vitro.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MPERRVFIIRHGERCDFAFGKSGLWINSFDSRGRYRPLDINLPRTLPKRADGWQGFAADTPLTEIGYLQSKLTGRALRDNGIEINHVFCSPALRCIQTTVGLLKGMGLDKRIQFSVEPGLYEWMVFARYARPCWIPPKDLKKLGYPVQENYVPCWTDKELRMNETLADFYQRSFGSINKILSECTEGNILIVAHGASLETCTRQLVGGDIRSTDDFYYLLQNTPYLSCVEVNSREGLWRLVGSPIPSFSHTYNRTFDPLQLVTKDLASLKREREGKDNMRTTQ
The following text describes a protein:
Function:
Involved in the protection against polyamine toxicity by regulating their concentration. Could also be involved in the negative control of sporulation as well as production of degradative enzymes such as alpha-amylase, levansucrase and alkaline phosphatase. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It possesses N1-acetyltransferase activity toward polyamine substrates including spermidine, spermine, aminopropylcadaverine, norspermidine, homospermidine, N(8)-acetylspermidine, diaminopropane and agmatine.
Sequence:
MSVKMKKCSREDLQTLQQLSIETFNDTFKEQNSPENMKAYLESAFNTEQLEKELSNMSSQFFFIYFDHEIAGYVKVNIDDAQSEEMGAESLEIERIYIKNSFQKHGLGKHLLNKAIEIALERNKKNIWLGVWEKNENAIAFYKKMGFVQTGAHSFYMGDEEQTDLIMAKTLI
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MTRHQYHFMAKNVGILRIATRAQPSAIFRSNGLRSFTPRAAPTMSATSASCFSTTSRSLAEPDKDGQEAAHHEESFEEFTARYEKEFDQVQDVFELQRNLNNAFAYDLVPSPSVVIAALKAARRVNDFPTAVRIFEGIKAKVENRGQYDQYLEELKPLREELGVSLKEDLYPEAK
The following text describes a protein:
Function:
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.
Subcellular Localization:
Nucleus.
Sequence:
MVEAELLTRGWHLSKDGIERCKDGVSAMSVDALTKRALDIDLKQIGSNALPADSGKAKSDKIQGPYVLQIQKVRNVGAPKANEESSMAPTLLRLQLTDGHTTCLGVVMETIPQISLNTPPGTKALLKGSVDMTNGFLMLTPSTLKVLGGKVEEMVERWELAKQLAHHTRSTLVGEGAPPPWVAFGQRNRIKNNTDIKQKMDGPGKKRTLNLDKNREQTEQDREFEEQRKAAIKELSQVRGQGGKKFGGGGTKAGGQDNESKENQGGTRSSYDRDRRGPGTGGTGPSESNRNSQPFGNYRELNYEKKPDDKSVSQLVSMGFSKEEALAALKKHSGNLEAAVDSLVSGASSQPSGSSGISNTRSTSDTRGTSDTRSTSDTRGTSGPPQRGRDRPERGSGFKGRRGRRGEDDEDDEFSSQPSAPTTLFDFLESKLGPKKAEAFKPKEKESKDNVEKNERSSRYDRDQSKPGRDASGNNYNHNVRETPPRFQKLQAQKQAQRQMGDTQQGSKDNRGGRRGDRPERFDDRRRDGKKSNEWTNDKEDASQGFKNESRFKNERRDGGYQDRNERRFDGQSRSGVADDQNDRGYQGRDRNNRSDKFQSERGRSSQNDGYQNDNGYQGRSNRRFDGQGKSGDTSRYNSNKNDNNTEKTYRLMERKKDNGPAQEENQSTKRSNGREAPQQDGIGNWKGPGQEENAKVKNQVNIRPDFKMLSQQSQPFIPQQQQQQMVSDGGRRVTDAGANQALNQGSVVRTKVMTNGPEMIPQSQSIPMLPFKVDDHCLSKYWEDHKFYKAQITAIHPSGKTCMVKFVEYGNFEEVLITDIMPCADHPWTAPPPSIAPVHHQQQQQPPQQQPPQQQQFMPAAPPFPQHYQQPPPIPQLVAGQTPLVQDYGNYDGSMNLTLEFRKGGEGPFIQKQGQDPGGFRGVDRRSQRPAQAFYQPPPRR
The following text describes a protein:
Function:
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
Sequence:
MGQDVRSPRGPRCIALVGPFQSGKTTLLEAILARTGAIPRAGSVDAGTSVGDATPEARHHKMTVGLTAATTSFMGDSYTFLDCPGSVEFAHDMRAALPAVDAAVVVCEADEKKLPQLQIILRELEELKIPRFLFLNKIDRANKRIRETLATLQPASRVPLVLRQIPIWKDELIEGFVDLALERAFIYREHKASEVIALAGGDRDREKEARFSMLEKLADHDDALMEQLLEDIQPPRDAVFDDLARELREGLICPVLLGAAARENGVLRLMKALRHEAPGVAETAKRLGAPESKDALGYVFKTLHSQHGGKLSLTRLLAGHLDDGATLQSSSGGAGRISGILAVNGAYDTKRAAAEAGDTVALAKLDPVKTGDMVSSGKTQPAALVTAEPTSAVLAISVAATDRKDDVKLGQALTRLHEEDPSLMVVQNAKTHDTVLWGQGEMHLRVASERLRDRFGVKVTSQPPAIGYQETIRKPITQRGRHKKQSGGHGQFGDVVLDIKPLPRGDGFKFAEKVVGGAVPRNYIPAVEEGVVDGLTRGPLGFPVTDVQVTLTDGSYHSVDSSDLAFRTAARVGLNEGLPQCQPVLLEPIHVVEIVCPTDATAKINAILSARRGQILGFDTRDGWSGWDCVRAMMPEAEIGELIVELRSATAGAGSFTRTFDHMAEVTGRAADQIIAAHQHAA
The following text describes a protein:
Function:
Involved in starch granule initiation in leaf chloroplasts. Binds and delivers suitable maltooligosaccharide substrates to starch synthase 4 (SS4).
Subcellular Localization:
Plastid, chloroplast. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Colocalizes with MFP1 to small patches distributed throughout the chloroplasts.
Domain:
Contains a C-terminal (456-532) carbohydrate-binding domain (CBM).
Sequence:
MVSINSGPISSFVSRYSMIDSDTLLHLSSFGSTFNPNYKAKACIRFARKVCGSTVLGFLEVKPRKKSCCSRCNGVSRMCNKRNLGWDSEGSKDLETEILEFMKNSEKPGMFPSKKDLIRSGRFDLVERIVNQGGWLSMGWDLDEQEEKVRVNENVTPQDLHIEKQLPNCNSPEMDKTLNHGDLDLSSNLSSSTEQVESRNDSGIEGILTRLEKERNLSLGISVRENGKSNGAMHDISPNGSVPWSSRIVTASEIQEVDGSRGSGEYAQSRYQGAKSVSGKPGLSDSPTSETWRTWSMRRAGFTDEDFEAAEISSSGLTGVKKDDTKKDSGDSMNGKDRIASSSEDVNKTHIKHRLQQLQSELSSVLHSLRSPPDKVVTSKDSETTAGNLENLSDDWEYKENEIIHAQNKLRSTRAKLAVLEGKMAMAIIDAQRIVREKQRRIDHASRALRLLRTASIVWPNSASEVLLTGSFDGWSTQRKMKKAENGVFSLSLKLYPGKYEIKFIVDGQWKVDPLRPIVTSGGYENNLLIIS
The following text describes a protein:
Function:
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
Subcellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein.
Sequence:
MFRSLFILCISLHGDDYASFFYRIYNFRFELCLLLDFWILKRTTFQTPKVSSFDEYYLKILLSDGTQKTYTNIPEIQLVLGATQPGAFYFSQKSLSQNEQDEIQAKTSNFTSNFFIDLLTEQVIKSIREIQILIFYEYDLDETISMNMQGYAFASLKSPHGISSASTIGQLRLSQRHPIFSGKTPRTKYNYSSYYNGLGQVLLDPIEIIENTIYNRNESIFYDYVSYIVPPTTALEVTNTPARETESDKDQFPIAFQTTTNDTTTNNTNTTQTVDIQKGVYLPVYLSHSSQLTINMTLQIPNKEMVMYQTEIIEALKFSWMQYLSIFLIFWFFGSLILEFVVQNKVFATQAVVNIPIALKSYSKLKLD
The following text describes a protein:
Function:
Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MLRRLACLTATLAAFSATPTTATTFTTLGGDNVANAVAQVSATDVSQYDTSTTTTQVNSTASVLGDNNTVTQVTSSGTSDQGQSSTIQQQQSTTGSAATQAGSTNTTHIQHSIRNGDVSSIGVNLGSWLVAEHWMTGAADFWKGVTDDDASKGEYTAISKASDPDTIRSNLDYHHSTFITESDIADIAAAGINTVRVPVGYWIVGFDNDDPSGEAAWEQFSNGTLKYLDVLIKDWAKTHNVAVLISTHAAKGSQNGADHSSPCDPGNSHWSAYDENVANTISMVTFLAARYKDEDAFLGIGLLNEPNASTDEDKLYAYYEQAYAAIRETGSDCVLSVAPLLYKQSADVMTDFMQAPTYINVWVEWHPYFVWGYENTSDYDLTNTAVKVNFQSSMSQWNARENHNRLFIGEWSFATAGKFGDDQEGYYEFCQAMVDVMYQAGAGFTFWSWRLYGDESGFNAWSLRSVLRDDRLKAIFFSGGSTQQS
The following text describes a protein:
Function:
Glutamine--tRNA ligase. Plays a critical role in brain development.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasm.
Sequence:
MAALDSLSLFTGLGLSEQKARETLKNTVLSAQLREAATQAQQTLGSSIDKATGTLLYGLASRLRDPRRLSFLVSYITSRKIHTETQLSAALEYVRSHPLDPINTEDFEQECGVGVVVTPEQIEEAVEAAINRHRAKLLVERYHFSMGLLMGEARAALKWADGKMIKHEVDMQVLHLLGPKTETDLEKKPKVAKARPEETDQRTAKDVVENGEVVVQTLSLMEQLRGEALKFHKPGENYKTPGYVTTPHTMDLLKQHLDITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAIYDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRDQAYVCHQRGEELKGHNPLPSPWRDRPIEESLLLFEAMRKGKFAEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDTWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVAAGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLEPLQVVITNFPATKALDIQVPNFPADETKGFHQVPFGSTVFIERMDFKEEPEPGYKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLKVTCRRADAGEKPKAFIHWVSQPLTCEIRLYERLFQHKNPEDPAEVPGGFLSDLNPASLQVVEAALVDCSVALAKPFDKFQFERLGYFSVDPDSNQGQLVFNRTVTLKEDPGKV
The following text describes a protein:
Function:
Involved in protein transport from endosomes to the vacuole.
Miscellaneous:
MISCELLANEOUS: Present with 2340 molecules/cell in log phase SD medium.
Subcellular Localization:
Endosome membrane; Multi-pass membrane protein.
Sequence:
MMEFKVSPLTKIISLSGFLALGFLLVILSCALFHNYYPLFDILIFLLAPIPNTIFNAGNKYHTSDFMSDSSNTGQDLAHFLTGMLVTSGIALPVVFYHCQLIGHLSCIMCMIGGLIIYSSIVIFKWFFKKDFNEDDSLFG
The following text describes a protein:
Function:
Involved in brain restructurization via hormonal control during metamorphosis. Implicated in N-glycan processing.
Sequence:
MSLAVSLRRALLVLLTGAIFILTVLYWNQGVTKAQAYNEALERPHSHHDASGFPIPVEKSWTYKCENDRCMRVGHHGKSAKRVSFISCSMTCGDVNIWPHPTQKFLLSSQTHSFSVEDVQLHVDTAHREVRKQLQLAFDWFLKDLRLIQRLDYVGSSSEPTVSESSSKSRHHADLEPAATLFGATFGVKKAGDLTSVQVKISVLKSGDLNFSLDNDETYQLSTQTEGHRLQVEIIANSYFGARHGLSTLQQLIWFDDEDHLLHTYANSKVKDAPKFRYRGLMLDTSRHFFSVESIKRTIVGMGLAKMNRFHWHLTDAQSFPYISRYYPELAVHGAYSESETYSEQDVREVAEFAKIYGVQVIPEIDAPAHAGNGWDWGPKRGMGELAMCINQQPWSFYCGEPPCGQLNPKNNYTYLILQRIYEELLQHTGPTDFFHLGGDEVNLDCWAQYFNDTDLRGLWCDFMLQAMARLKLANNGVAPKHVAVWSSALTNTKCLPNSQFTVQVWGGSTWQENYDLLDNGYNVIFSHVDAWYLDCGFGSWRATGDAACAPYRTWQNVYKHRPWERMRLDKKRKKQVLGGEVCMWTEQVDENQLDNRLWPRTAALAERLWTDPSDDHDMDIVPPDVFRRISLFRNRLVELGIRAEALFPKYCAQNPGECI
The following text describes a protein:
Function:
Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSEEEKAELENMQVESEAKTSENDQTIDTKVDVADVTTHVDEDLDNKEEALDFSEDELSDLDENQFENFDESKIGREAEEPTIYNLPTFKKKQEPNTIEENLEVPRKVRKEQKPRRRRGKRSSTVDALNDELNELGENEEEVLTEQKQLDPTLAAKKELDLQMDAVLKPTRTKKRSNEDNLEQMADDEVLRLREQMRLAALRDAELNSEQLPATEKLKMLPLVDAVLRKTHLYDTILDNNVLDSVRMWLEPLPDRSLPALNIQRSLMDILTKLPIQTEHLRESKIGRIVLFYTISKKPEPFIKRIADNLVSEWSRPIIKRSANYRDRAVGVASFNPEVFQTRRRRDLAAAESNDDAQASRTGRTVIPRSIDSRYQVAPRVRLNPTAMTIAGRMKPADTEQVRKLKAKMKAIRSKSSKKSGVSIEGRGL
The following text describes a protein:
Function:
Catalyzes the conversion of methylglyoxal (MG) or glyoxal (GO) to D-lactate or glycolic acid respectively in a single glutathione (GSH)-independent step. May play a role in detoxifying endogenously produced glyoxals. Involved in protection against glyoxal-induced cell death. Protects dopaminergic neurons from glyoxal-dependent neuronal degeneration.
Subcellular Localization:
Cytoplasm.
Sequence:
MAAQKSALILLPPEDAEEIEVIVTGDVLVRGGLQVLYAGSSTEPVKCAKGARIVPDVALKDVKNKTFDIIIIPGGPGCSKLAECPVIGELLKTQVKSGGLIGAICAGPTVLLAHGIVAERVTCHYTVKDKMTEGGYKYLDDNVVISDRVITSKGPGTAFEFALKIVETLEGPEKTNSLLKPLCLAK
The following text describes a protein:
Function:
RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPREVKKRGRRAAAKRAEEEKEDVDLKVYENDEDYVTFDADGGVAGGHDDEENDGYDNETPYNPLDLKQMPFFGFLDDQESEYFKTAESTLAVDAFGSPEEKLGFISGLLDEARGKELKLVTNQICSKLMERLILLANDEQIRALFEVFSGYFVDLSRHKYSSHCVETLLVRGAAIVEKEVLDPNFDGDSEDSMEKRFLTLANDMKDYIQDLISNPYASHVIRVLLLILGGQTLPSPTSSEGNSSVLRSKKSRTARRNIDIKDSEENDRAYQIPGAFHDALEAIVSGFSKRLKPTAARELAIGQVSSPVVQLLIDSEATTSEQRPLLNTIFADTEDRDSSEEAFVEHLLSDAVGSHFLQNVLQKAPEAFVERLYRLYMSQRVQKLVRRDYAGFVIETCMQRLPEADVHHIIDTAMGEIPYLVENNNLTMVRILLTRAAAANYKATDVANAVLKTFDTDSTDPKLLQKVLQLDEKNPYKPHEASSPGLHRCLVLQQLVEASPEVLATAFVGLNSGDVDVIKMAKHQSYSRLLEKCLRPSINTIERRKFLNKINGQCVDLARDPFASHVMDRLWNFTYKMNNFREKIANELVADEDLKENTYGKAVWRNWSLDKFLRRKSDWWVTLHATDDALAKEYEELGIPLDAKSLANPGQKRFGRGGARIITRGGGTFPRGGGRGRGGFRGGRGGAPRGGFGGSDRGGFKRANGGDGEDASGDRSRKKVRNE
The following text describes a protein:
Function:
Transcription regulator that modulates expression mediated by transcription factors of the GATA family such as pnr and srp. Represses transcription of proneural achaete-scute complex (AS-C), which is usually activated by pnr. Involved in cardiogenesis, blood, and eye development. During hematopoiesis, it is required to restrict the number of crystal cells, probably via its interaction with the isoform SrpNC of srp. Negatively regulates expression of sr. Probably acts by interacting with the GATA-type zinc finger of proteins such as pnr and srp, possibly antagonizing the interaction between the GATA-type zinc finger and some cofactor.
Subcellular Localization:
Nucleus.
Domain:
The CCHC FOG-type zinc fingers 1, 4 and 5 directly bind to GATA-type zinc fingers. The Tyr residue adjacent to the last Cys of the CCHC FOG-type zinc finger is essential for the interaction with GATA-type zinc fingers.
Sequence:
MLSSNTRGDCSDTAEEMTVDSRDSKDLSAQDIGEQKQQQMEDQLEDQLNDSRDPQNNNNNIDDDADEDAEFEEPEKANPQQDQDLGETEMEQEHDLQQEDLQQELPANSPSTPPRSPSSPQLIPKLEQPATPPSEPEASPCPSPSPCPTPKYPKVRLNALLASDPALKPDAKELTLPDSRLLAPPPLVKPDTQAQPEVAEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRIKDTDEAGSDKSGAGGSGATAGDAAGLTGGSTEPPAKMARTGKQYGCTQCSYSADKKVSLNRHMRMHQTSPAAPTLAGLPSLLQNGIAPPGVTPNPMEDSSSQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPDASPGAGSGPGSAGGSIGVSAQAATPGKLSPQARNKTPTPAMVAVAAAAAAAAASLQATPHSHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTIKPLATALVGATLEPERPSAPSSAAEATEAKSSPPEPKRKEAGLTRESAPLDLSLRRSPITLNSLSLRQRQLRNALLDVEEVLLAGVGTGKENVETPRGGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPGLNVAVPHLLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGSSGAAAFPPASLPAQTSSGNPGSGGSAGGAQQPQIYVKKGVSKCMECNIVFCKYENYLAHKQHYCSARSQEGASEVDVKSAVSPSIAGAGGLGAGAAEAASSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAVAAPAATPTDPGQLGMPKEKCGKCKTLHEIGLPCPPPVANPLAAPTVNPQPATNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEELYMTCIFEEDASALSQELVTPTGASTTTGHDSMDHPSQMFNCDYCNYVSTYKGNVLRHMKLMHPHVAINSPSISPDTRDQDVTSNPTTNQHSNSDVSNGEAPSFHIKSEPLDPPPTVNLVHENNNSPIATPHIKAEPIEVGADAAPGGLVPPMTSPLGNSSSVAAAAAAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPIRPEASDSPSPNHLGGGVAVGLGIGGLVGGHGQQKNKENLQEAAI
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSISVKVLTPETFLEDVPSIYKMEKIWECNGSFKKKQRIEGKPSTRLKTIQAVPPKEAGGSEYSKYSQTSSPEPDLFPQQGVSVVMQCQKGDKQRGSSTMHSNRGQYNQVYSRKKYPKVKKCQNVLGHERGNSFLQNNELCPRQRTDRKGKCTELTKRGKTDLAKRSHLQSSERWYKCNECGKAFRYEVSLKVHYRIHTGEKPFECSECGRAFCQRIDLIRHIRIHTGEKPFKCCDCGKAFSRSTSLTLHQRTHTGEKPYECNVCGKTFRSSSHLSGHRKSTHEGIRLHECNVCGKAFSRKYDLTNHSRIHTGERPYECSGCGKTFCLKSSFTFHFRSHTGEKPFKCSECGKAFYRKLDFINHNRTHTGEQPIQCMFSLGEIH