lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Putative uridine kinase identified in a screen for mutants with increased levels of rDNA transcription.
Miscellaneous:
MISCELLANEOUS: Present with 4280 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDRKAVEEKRIVISIGGGHATGVGAIALDLQNTFKSLYNSINIRVINLDNMIEGNIKSYNNNDYDFDNILNLVYEKHAVTSQNDMIQHDYEDPIDLIIVCGCYALYDKRINEISQLKVFLDSDADKRLISLIKKKNVGSNEQLAQLITEYMDHLRPEMQQYIEPTRTFADLIIPSTNENLGRAVLVDGIVKAIEDTKSQIEGNNTNNKIRPRLWDFEAETMDLEKDRYYDLS
The following text describes a protein:
Function:
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (By similarity). TFIID recognizes and binds promoters via its subunit tbp-1, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (By similarity). The TFIID complex consists of tbp-1 and TBP-associated factors (TAFs), including taf-10 (By similarity). Essential for early embryonic development, but not required for transcription of some genes; probably acts via activating transcription initiation by RNA Pol II, as part of the TFIID complex.
Subcellular Localization:
Nucleus.
Sequence:
MNDPEQYEPSSSTESVLMPPPALPQYFQRPAAAPQVYSTLEPSVQNLRSSLHKPLTGNQQQFVQKTLENVQKNPSQDDTHEFINQLADYPPTIPDSVTLHFLKSAGVDGSDPRVTRMISLAAQKHVSDIILDAMTSARMKGLGQTKKGTKDTKYTLTEELLDEILKEYGHQNTRPPYHT
The following text describes a protein:
Function:
Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Sequence:
MIYVKRLVEKAILPKKGSLKAAGYDLFSAEDSVVPAKGKQVIKTGISMALLEGTYGRIAPRSGLAAKNFIDVGAGVIDEDYRGEICVLLFNFGDNDFKVNYGDRIAQMVIEYVVQTDIQETDNLTETQRGEGGFGSTGVKLIQNTNNQSQQLKQKLQNIQQLNHDQPEPWQELTILDLYSLFSNGHINSKQKQQLGEITMKGDKKVYELFKKNEGKNEQIIIQQLHNLIEE
The following text describes a protein:
Function:
A probable ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
Subcellular Localization:
Nucleus. Note=Colocalizes with PCNA within the replication foci in S-phase cells.
Sequence:
MPKITLNGVAVDFPFEPYKCQEEYMSKVLECLQKRVNGILESPTGTGKTLCLLCSTLAWREHLRDAISAHKIAERVQGELFLDRTLSSWGDAAADAGAACYADIPKIIYASRTHSQLTQVIRELRNTSYRPRVCVLGSREQLCIHPEVKKQESNHMQIHLCRKKVASRSCHFYNNVEEKSLEQELATPILDIEDLVKSGNKHKLCPYYLSRNLKQQADIIFMPYNYLLDTKSRRAHSIDLKGTVVIFDEAHNVEKMCEETASFDLTPHDVASGLDVLDQVLEEQTKAAQQDELRSEFSADSVNSGLHMELEDLAKLKMILLRLEAAIDAVELPGDHSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRTGLFSNTAGLQKLSDIIQIVFSADPAEGTPGSLGGPGACQSYKVHIHPDAGHHRKGPRSDAWSSTAARKPELRLLVTRGWVCAGPPVAFGVKLACPGRGKVLSYWCFSPGHSMRQLVQQGVRTVILTSGTLAPVSSFALEMQIPFPVCLENPHVIHQQQIWVGIVSRGPDGAQLSSAFDKRFSEACLSSLGKALGNIARVVPHGLLVFFPSYPVLERSLQFWRTHDSAGKLEALKPVFVEPRNKGGFSEVVDAYYARVACPGSTGATFLAVCRGKASEGLDFADMNGRGVIITGLPYPPRMDPRVVLKMQFLDEIKNHRGPGGQLLSGHEWYRQQASRAVNQAIGRVIRHRHDYGAIFLCDHRFAHVDARAQLPSWVRPHVRVYDNFGPVIRDVAQFFRVAQNTMPVPAPLLAAPSLGEGAAAAVVAALPGPLSTRKAKSLDVHVPSLRRTPTGSPAARDTESSLCVEYEQELGLAPRRPVGLLAALEHSEQLAGGPGDKAPPGEEQALHLPTSSVPREKRAAQEQRAGRRKIRVLGDRQEGPAAETQAGRAKLYMVAVKQALSQASFDTFTRALQDYKGSDDFEALLACLGPLFAEDPKKHGLLQGFYQFVRPHHKQRFEEACVQRTGRSCGYQPEHSLPQRRAAAPAPRGSRECDLKLTLSQGVARQLDPGQHLNQGGPHLLSGPAPAGDPSSRPGEEPRDTAAQRQGPPAASAYLADVRTALGSAGCSQLLAALTAYKRDDDLEKVVAVVAALTTSRPEDFPLLQRFSMFLRPHHKQRFRQTCADLMGPAAPSTGAAPSTGPGSGPQEGAPTTPLDLTPPGAPQQEKPETTQSKISAFFPPRPVGDVGAPRQPPSAPRRHAQPEWAGLACQGCGLEDTVPFQCPACDFHRCWACWRRLLQASRTCPACHAPARKQSIAQVFWPEPR
The following text describes a protein:
Function:
Structural component of the gap junctions.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MGFSAVDKLIRPFLQLHEWDNGAERIVHTTTIQILLCFGFLVTSNMMFGQPITCLVLPETPDSSTNYFHDFCFYQDKLRISPMQPSLKREQDMGTMHLNFITREEVAVTYYQWTPFIIFLQVAMCLAPALMWKFFGLHYFYGNDFAAIIRSLASKKKDDKMDSNDSDYKVDARDTLRWLKLKKREQWGMHTTMLVYVTMKWMTFASLLLQFYMMANIYASGELLWGVHISYELLNGVYKNLYTGVFPQIVGCKTHRTQTGGVVNEFTMRCILPQNFVNSKVFLFLYWWYVLAMFVSIFSAVQFTLMLILPKYQRYATKSLLPTLEFFVEDAERNNRTIVHGHSDPLDHFVDYMGNDGYLLLQCASVPLSVVKIRFFLNSLYEVVLPQRGTDRQDPIFAKKKNRLLTEDDDDQSDYFQKKEHSAKDKQMLMTDANSFSEPLLSHSSVFQTRVISG
The following text describes a protein:
Function:
Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
Subcellular Localization:
Periplasm. Note=Is capable of associating with the outer membrane.
Domain:
The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.
Sequence:
MKNWRTLILGLVICANTAFAAPQEVDKVAAVVDNGVVLQSDIDGLLQSVKMNAQQSGQQVPDDSTLRHQILERLIMDNIQLQMAKKMGITITDQALDKAIADIAAQNRMTLAQMRSRLAADGLSYDTYREQIRKEMLTSEVRNNEVRRRITILPQEVESLAKQMGNQVSGDTELNLSHILIPLPENPTQQQVDQAEDLANKLVADIKGGADFGKLAIANSADSQALKGGQMGWGKLQELPSLFAERLQSAHKGEIVGPIRSGVGFHILKVNDMRGADQTISVTEVNARHILLKPSPMMTDEQARAKLEAAAAEIKSGKTSFATIAKEISQDPGSAMQGGELGWASPDIYDPAFRDALMKLKKGEISAPVHSSFGWHLIQLVDTRQVDKTDAAQKERAYRMLFNRKFAEEAQTWMQEQRAAAYVKILDGSNAQPQ
The following text describes a protein:
Function:
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MTREMRHTSLLKGLLCLFAIQLPLVNAQVAEIEKATNDSLLWGPYRPNLYFGVRPRIPKSLMGGLLWSKVEDYSSVQNTFRHTCEQHELDGYGWDEYDVRSGGRQTIHDPANNIDITTEFIKFPGGEHGGSWGARIKGTPREDASPNVRSTVVWYNTLEGLGSLEVDGADVDEPGFKGDVTLKGQTPELGEFEITVTEGTGKHPLTGHPSYDDKPLDRTLVHSGQVPEEALWQTKAVLFAHMKGQVDQLVAKWGEENPPPPAQVYTIQNLPGRGNMHLIQKVFEGPFEFDIIFSSASAPTKITSEDLTQQIGSVTSGFATRFASIFKPQPPFVKERYEEFSKSLFSNLIGGIGYFYGDSRVDRSYDSAYDEDNEGFWEDAAEARARNQADAVGPSELFTAIPSRPFFPRGFLWDEGFHLLPVIDWDADLTLDIIKSWFNLVDENGWIGREQILGAEARSKVPEEFQVQYPHYANPPTLFMVITSFLDKLDAQKTDSTNKQLLHEKSYFMQLANREAALQYLRTLYPLLKRHYFWFRETQAGDIKSYDREAFSTKEGYRWRGRTPQHILTSGLDDYPRAQPPHPGELHVDLISWMGMMTRAIKRIAIYLDEEEDAKEFAKYDEAIVRNIDDLHWSDKAKTYCDATIDDYEEHSLVCHKGYISLFPFLTGLVDKDSKRLGAILDLIEDEEELWSPYGIRSLSKSDEFYHTAEDYWRGPVWMPINYLAVSQLLNIAQQKGPHQERARKLYTELRKNLVNTVYESWKETGFAWEQYNPETGKGQRTQHFTGWTSLVVKIMAMPDLSSERVRDEL
The following text describes a protein:
Function:
Involved in the recruitment of clathrin to the Golgi network and endosomes to form clathrin coated vesicles. Plays a role in the trafficking of clathrin between the Golgi network and endosomes. Binds to membranes enriched in phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2) and, in association with VPS27, is involved in protein sorting at the multivesicular body (MVB).
Subcellular Localization:
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Note=Associates with the trans Golgi network (TGN) and endosomal clathrin coats.
Sequence:
MSLEDTLANMSLYDAKKYFRKAQNVVFNYTEMEGKVREATNNEPWGASSTLMDQISQGTYNFREREEILSMIFRRFTEKAGSEWRQIYKALQLLDYLIKHGSERFIDDTRNSINLIRILETFHYIDSQGRDQGINVRTRVKALIELLSDDNKIRAERKKARETAKKYKGVAGGSASADGSLNSKAGFTSTKVHGISVSADFDSDNEDNEDGSFSQNGYNDNASRATSTPGQGKQEPEDFVDFFSSESSKPSKELIQEDEKKADEEEDDDDEFSEFQSAVPVTNPANSFNLLNTSPIEGMPATTSSMPFYNSSTTDQGKITPAIAEPKKVDPFSSLFSTAKASAEAPSAPKASQAKAAASNPVSNSTTALSTDQDDDDEFGEMHGGAVQQEQNTNNNHTSSKEIDLLSF
The following text describes a protein:
Function:
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
Sequence:
MAARGLKGKAAAQEHGGLKIMLVSSDKQRFCLPEPAARVSKVISKSICGYLTDADITLEFPAEAVNMVVEYCKRKAADGVEMTHGWEREYLRDLGQAQLYEVLHAAGNPEIEELVDLACKRVANMISGKAPAEIRRIFGIDNDEFTSEQREEIRRDNSWIDMTAEEQAELELVFFFAVITSF
The following text describes a protein:
Function:
Endonuclease for the repair of UV-irradiated DNA. Involved in the excision of cyclobutane pyrimidine dimers (CPD) and 6-4 pyrimidine pyrimidones (6-4PP) which forms the UV damage repair (UVDR) pathway. Also functions in oxidative damage repair in vivo. Provides back-up AP endonuclease activity to apn2 together with apn1.
Sequence:
MLRLLKRNIQISKRIVFTILKQKAFKGNHPCVPSVCTITYSRFHCLPDTLKSLLPMSSKTTLSMLPQVNIGANSFSAETPVDLKKENETELANISGPHKKSTSTSTRKRARSSKKKATDSVSDKIDESVASYDSSTHLRRSSRSKKPVNYNSSSESESEEQISKATKKVKQKEEEEYVEEVDEKSLKNESSSDEFEPVVPEQLETPISKRRRSRSSAKNLEKESTMNLDDHAPREMFDCLDKPIPWRGRLGYACLNTILRSMKERVFCSRTCRITTIQRDGLESVKQLGTQNVLDLIKLVEWNHNFGIHFMRVSSDLFPFASHAKYGYTLEFAQSHLEEVGKLANKYNHRLTMHPGQYTQIASPREVVVDSAIRDLAYHDEILSRMKLNEQLNKDAVLIIHLGGTFEGKKETLDRFRKNYQRLSDSVKARLVLENDDVSWSVQDLLPLCQELNIPLVLDWHHHNIVPGTLREGSLDLMPLIPTIRETWTRKGITQKQHYSESADPTAISGMKRRAHSDRVFDFPPCDPTMDLMIEAKEKEQAVFELCRRYELQNPPCPLEIMGPEYDQTRDGYYPPGAEKRLTARKRRSRKEEVEEDEK
The following text describes a protein:
Function:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus.
Sequence:
MPPQQWEFHLPLAPEELLKSGGVNQYVVQEVLTVSQLRPQLTAFQGAFRFQGPLALLEHFDTFYSVLHHFRSADPRLPEDALELLMKVVSRHSQELPAVLDAAALSPADRGAHLNALKMSCYALTRLLESFEATATAGKTSLVGLDPGGKGRKGCPKTFGFDWEEERPQVLQLLTQLLQLDVRRLWPRALVEEEFVSLVTGCCYRLLENPTVSHQKNRATREGITHLLGVALTRYNHMLSATLKITQMLQHFEHVAPVLVGAVSCWATDYGMKTIVGEIVREIGQKCPQELGRDPAGAKGYAAFLTELAERVPAVLMTSMSVLLDHLDGESYLMRNAVLAAMAELLLQLLNGDQLDQRARDTRDQFLDTLQIHGHDVHSFVRSRVLQLFARIVQQKALPLTRFQTVVALAVERLQDKSVLVCKNAIQLLAAFLANNPFTCKLSCADLAGPLEKETRKLQEFGSLARRPAGRRAELDPEEEWAAMLPELKLTLHRLLAPGTGDEEPAPPAIDHADAAEQTAAHIRQLLAKASYEPAILLARAAVGHFQGAEPFNCSDPDGPEDVRLLSLLHRLFSAAGPPPPRSGEQPTAGEPGCWGWAGPGEQAREELVKQEMLVQYLQDAYSFSLQVTEAVGAVSKMMYENTSTVVQEAIEFFVTVSRFGVPQALMGVRRMLPLIWSKEPGIREAVLDAYRQLYLPAGRDPARAKAQTLVQNLSLLLLEASAATVQCLGEILREFVRNGELAPAVTQLLWEMVTEKVPCSPPERRTAVRLLGMMARGKPEIVGSNLDTLVSVGLAEKAPADYRLAREVCLAIAAIADGGKPTTGGSAPPFRLPQDHRLFEQLQEVVVAGFTSPDALWIPFAEVAVALVYQLAEGPEVICAQILRRCGQRATETLQEPLAPKEGSEEAPRLPTFVLSHLVSLAGDVALQQLVHLERAVSAELRRRRVLREEQDDKTKKAAEKNLTGETTMEEELGLVGASADDTEAELIRSICEAELLEDKQLLSAFVPLLLKVCNNPGLYSDPALSSAASLALGKFCMISASFCDSQLRLLFTLLEKSPLPVVRSNLMVAVGDLAIRFPNLVEPWTPHLYARLRDPAAAVRRTAGRVMTHLILKDLVKVKGQVSEMAVLLVDEDPEIAALAKNFFNELASKGNAVYNLLPDIISRLSDPQGGVEEQPFRTIMRQLLSYITKDKQTESLVEKLCQRFRTARTERQYRDLAHCLALLPLSERGLRKMQDNFDCFADKLTDEAVFGAFSQAVGKLRRWAKPEGKVLIDEFEQKLRAGHNRGLDSDEEPSAEQGPGEAQRASARPSTGMSPPPPLPPSPWGRWSHLARGWGARELYHGEAARPRGWSMLLGVGRSWVPVPAPPRVCSVTLGKTPHFSGPPLLHL
The following text describes a protein:
Function:
Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion. Plays a critical role in the determination of bone quality and strength by providing phosphate for bone mineralization. Required to maintain normal cerebrospinal fluid phosphate levels. Mediates phosphate-induced calcification of vascular smooth muscle cells (VCMCs) and can functionally compensate for loss of SLC20A1 in VCMCs.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Sequence:
MAMDGYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSVLLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVGSTIGFSLVAIGPKGVQWMELVKIVASWFISPLLSGFMSGVLFILIRMFILTKEDPVPNGLQALPLFYAATIAINVFSIMYTGAPVLGLSLPIWAIALISFGVALLFAFFVWLFVCPWMKRKIAGRLEKESALSRASDESLRKVQEAESPGFKELPGAKPSDDSAVPLTSLAGEAVGASEGTSAGNHPRASYGRALSMTHGSAKSPISNGTFGFEGHMRNDGHVYHTVHKDSGLYKDLLHKIHVDRGSEEKPTQENNYRLLRRNNSYTCYTAAICGMPVHTTFRASDTSSAPEDSEKLVGDSVSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMRLASELADPDRPHEDPTEEEKEEKDSAEVHLLFHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYQQGGVTQEAATPVWLLFYGGVGICTGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWIRSRKAVDWRLFRNIFVAWFVTVPVAGLFSAAIMALLMYICGLFSSSR
The following text describes a protein:
Function:
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
Sequence:
MSKIGFNPIKIKSFSKIKTYDDTLPSLKYVVLEPAGFPIRVSSENVKVSTDDPILFNIYARDQWIGEIVKEGDYLFDNSILPDYAFKVISTYPKEGGMITSETVFKLQTPKKVLRTQFKKAKFSEIIGQEEAKKKCRIIMKYLENPKLFGEWAPKNVLFYGPPGTGKTLMARALATETNSSFILVKAPELIGEHVGDASKMIRELYQRASESAPCIVFIDELDAIGLSREYQSLRGDVSEVVNALLTELDGIKENEGVVTIAATNNPAMLDPAIRSRFEEEIEFKLPNDEERLKIMELYAKKMPLPVKANLKEFVEKTKGFSGRDIKEKFLKPALHRAILEDRDYVSKEDLEWALKKILGNRREAPQHLYL
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MSLPLPPRVDPKIWQICVGPDVKIPKIHSKVYYFPRGHLEHACSSPTAATRTILDRYRSSIPCIVSSVDLFVDPHTDEVFAKLLLTPVTDQEPPPPVVPGQEDDDGDNLVSYVKTLTQSDCTRVLCVPIECSNLIFPKLDLDKSQSITVTDLKNQEWRYTYTYSNSSRLHTGWLNFVREKKLVANDSVVFIKNSAGKISVGIRRNTKFTTDEAAEGSENLTDEIKVLDAAELAEKNTAFDVVYYPTASGWRDFVVDAKTVDDAMKIGWKSGMRVKLPLKKYESSNSKMTISQLKGTISFVFNHSSNVPNWRILEVNWDGLDIPQIPNLVNPWQVEVYNIHAPSTSSSTVNNPRLAESSSPQQIPYSMPGTSGPMSQAPSEVSSLAYLCNIGLQSQLGTR
The following text describes a protein:
Function:
Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
Sequence:
MMACNQELLSPRGLDLLSKNSHSNLTPTIFYPSDHNIDLQSFSTHALSVVRTLKKAGYEAYIVGGCIRDLLLKTEPKDFDISTSAKPEEVKTLFKNCILVGKRFRLAHIRFPNQIIEVATFRSGSNEEDSLITKDNLWGSAEEDVLRRDFTINGLFYDPSAEIIIDYTGGVEDLKNRYLRTIGDPFLRFKQDPVRMLRLLKILSRYAFTVDPKTLEALQESCHELVKSSQPRVFEEIIKVLSSGESTIFFQLASEHRVLEILFPYMAKAFSLSKTLQDQTFACLTALDTKIQKRSFCSERHFLLAILLFPIVNFNVRYKYSQYPTMTIQSIFDYIRNFLTEFFADSFTSCSKKNFILTTLLLQMQYRLTPLNAMKKEKKSFFNRRLLRHAYFREALYLLEIRSKVYPKVEATYGEWLKHYELASE
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) signaling for stomatal closure in leaves, and controls water loss during leaf senescence. Activated by the NAC029/NAP transcription factor during ABA signaling in senescing leaves. Functions as a negative regulator of osmotic stress and ABA signaling. Acts as a negative regulator of response to drought.
Subcellular Localization:
Golgi apparatus. Nucleus.
Sequence:
MAEICYENETMMIETTATVVKKATTTTRRRERSSSQAARRRRMEIRRFKFVSGEQEPVFVDGDLQRRRRRESTVAASTSTVFYETAKEVVVLCESLSSTVVALPDPEAYPKYGVASVCGRRREMEDAVAVHPFFSRHQTEYSSTGFHYCGVYDGHGCSHVAMKCRERLHELVREEFEADADWEKSMARSFTRMDMEVVALNADGAAKCRCELQRPDCDAVGSTAVVSVLTPEKIIVANCGDSRAVLCRNGKAIALSSDHKPDRPDELDRIQAAGGRVIYWDGPRVLGVLAMSRAIGDNYLKPYVISRPEVTVTDRANGDDFLILASDGLWDVVSNETACSVVRMCLRGKVNGQVSSSPEREMTGVGAGNVVVGGGDLPDKACEEASLLLTRLALARQSSDNVSVVVVDLRRDT
The following text describes a protein:
Function:
Toxic component of a type II toxin-antitoxin (TA) system. An RNase. The cognate antitoxin is VapB8 (By similarity).
Sequence:
MTEGEVGVGLLDTSVFIARESGGAIADLPERVALSVMTIGELQLGLLNAGDSATRSRRADTLALARTADQIPVSEAVMISLARLVADCRAAGVRRSVKLTDALIAATAEIKV
The following text describes a protein:
Function:
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Subcellular Localization:
Mitochondrion.
Sequence:
MLLQRFFTRALHSTRQLYAGSGGSGGLEKSALAALRKKTGYTFANCKKALEKHNNDVGLAEKWLHEQAQTLGWSKATKVADRATAHGLIGVLIRGNRGAMVELNCETDFVARNDTFKRFVDHVACMCLQYTDLTDFDGDLWKLGFDADALRNLRTEEGRTLGDHLALLIGAIGENATIRRALCFKANNDLKLVGYAHPAPTNVGTTEGITQVGKYGAIVAYRSTHPLLDFEFHKSICQQIVGMKPTKIGEYDKDKPAENKDDETCLIHQEYLLDADKTVGEALQEHNCEIVDYHRFECGEHTERSLEAIIRSQHQSSN
The following text describes a protein:
Function:
Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.
Sequence:
MEMNPIITRVTQRIIARSAATRTAYLQRISAAKEHTVHRSQLACGNLAHGFAACQPEDKAALKNRVRSDIAIITSYNDMLSAHQPYEHYPQQLKDALHEVGAIGQVAGGVPAMCDGVTQGQDGMELSLMSRDVIAMSAAIGLSHNMFDGALYLGVCDKIVPGLLMAALSFGHLPAIFVPAGPMASGLPNKEKVRIRQLYAEGKVDRQALLEAEAASYHSAGTCTFYGTANSNQMVMEVMGLHLPGASFIQPNTPLRDALTAAAARQITRLTETGINCIDGNHIDVNHINSSHINSSYLPVGQLVDEKVVVNGIVALLATGGSTNHTLHLVAMARAAGIIINWDDFSELSEAVPQLCRIYPNGPADINYFQASGGVALLVNMLLQGGLLHEEVHTVAGFGLQRYTQEPYLAAGKLQWRPGPQQSLDATVIASLEQPFSAQGGTKVLNGNLGRAVMKTSAVPREHQVIEGPARVFESQHDVEAAFESGDLDRDCVVVVRYQGPQAIGMPELHKLMPPLGVLLDRGFKVALVTDGRLSGASGKVPSAIHVTPEAYCGGLLANVRNGDRIRVDGVSGELSLLVDEAELATRDSPLPAISAFHVGCGRELFGALREQLSGAEQGACCIRF
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MLLSTITAEIFTSMDQLQRLSTVEKNLHETLDLYIMQERKRLEDLKGIYAAKKEELKKRERDDEVYHPLDVFRVINRVSSEWSTVEKLVRFNPHKSEFIQEIRNYHASFPSDADFDGTRAAMLRLQKVYNISSQSISSGVIPGQRNAHARLSGIDSYQIGRKAYEDGNIIQAKAWMENTLRMMGTSESLQNLTGHVVVSRNDVLNHLAFLEYKIGDLARSLRFYREMLVNDPNDTELQSNIRKLKHLIAKQPHLNVTSPPNTANRIEDDGDDELSREEMAEYTRLCRPNSQTRLPSSNKQLTCSYLNKHPGLKLKPVAMEIVSVNPQITLFHNVLSEMEIEQMLELARPRLRRARVNNLETGEIEDVDYRISQIAWLSDSDGDIVRRINRRVGFITGLNTNTGECLQVNNYGVGGHYEPHFDHSLDMENSPIASLGQGNRIATFMFYLSEVEAGGSTVFIKTGVKTNPFKGGAVFWYNLKKSGEGDWDSLHAGCPVLIGNKWVANKWLHEHGNEFTRQCGLTEDED
The following text describes a protein:
Function:
Required for ciliogenesis.
Subcellular Localization:
Cell projection, cilium membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Sequence:
MSLFKARDWWSASLGEKEEFDQGCLCVADVDNSGTAHDKIIVGSFSGYLRIFSPHPLKPGDGMQAEDLLLEVQLRDPVLQVEVGKFVSGTEILHLAVLHPRKLCVYSVSGTLGNVEHGNQYQMKLMYEHNLQRTACSMTHGPFGGVKGRDLICIQSMDGMLMFFEQESYAFGRYLPGFLLPGPLSYSPKTDSFVTVSSSRQVESYKYQVLAVATDADSRKENEQQKMGAGKKVVADWILNIGEQALDISIVSFNQTSFSIFVLGERNFFCLKESGQIRFMKKLDYSPSCFHPYSSVNDGTINTLVGNHNNMLLVYQDVTLKWAAQLSQTPVAVKVANFRDLKGVIVTLSESGQLQCSYLGTDPSLFQVPKVESRDINYEDLDVEMKELQRIIKEATKTQDILPKMEKDDDLTLVATVLPDLDSVSQAVDGEVESEVIPSVSVKLCVRSRLTLQKAVLLISTPAPLALTQDQFIFDSLEPGVSKTASASVFLKGNYPPADLEGSAVVSYSKPTELNPEGVPRIVQCKFRLPLKLVCFPVQPSKVANHKLTIDTNKPPVNLINLFPEFIDQVEEDQVSVVGFQLLAGQKVTLLASKTSQRYRIQSEQFEDLWLITREFILRFQDYFLKQGIKDFTCSFSGPVPLQEYFELIDQHFELRLNGEKYEALLSERAVQFRAIQRLLLTRFKDKTPTPLQNLDTLLDGTYRQVIGIADAAEELQRNLFRAFTRLKSATQLVILLIGLWQKLNKEQIAILEGTFLPLLKDGQELGWEESVDAALSHLLRTCLSKSSKEQALNLTSHLSIPKDTSRLKKHITLLCERMSKGGRLSLSADSGSQQAAEMQGTPINPSVS
The following text describes a protein:
Function:
Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate.
Subcellular Localization:
Periplasm.
Sequence:
MQLRKLTTAMLVMGLSAGLAHAEDGAPAAGSTLDKIAKNGVIVVGHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLLQNGTFDFECGSTTNNLERQKQAAFSDTIFVVGTRLLTKKGGDIKDFPDLKGKAVVVTSGTTSEILLHKLNEEQKMGMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKKPDNWEIVGKPQSQEAYGCMLRKNDPEFKKLMDDTIAQAQTSGEAEKWFDKWFKNPIPPKNLNMNFELSDEMKALFKAPNDKALN
The following text describes a protein:
Function:
Modulates RecA activity through direct physical interaction. Can inhibit both RecA recombinase and coprotease activities. May have a regulatory role during the SOS response. Inhibits DNA strand exchange in vitro.
Subcellular Localization:
Cytoplasm.
Sequence:
MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQEIWRNFAD
The following text describes a protein:
Function:
Mediates the interactions of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA. ADP-binding activates Hda to hydrolyze DnaA-ATP; Hda monomers bind to ADP with about 200-fold greater affinity than for ATP. RIDA function can be genetically separated from viability, suggesting this protein has another function as well; Suppresses the toxic effect of overexpressing a TrfA N-terminal 163 residue fragment. Inhibits inner membrane-associated plasmid IncP-alpha RK2 replication probably by interacting with plasmid-encoded TrfA.
Miscellaneous:
MISCELLANEOUS: Starts with a CTG codon; MISCELLANEOUS: There are about 50 homodimers per cell in strains C600 and K12 / MG1655.
Subcellular Localization:
Cell inner membrane. Note=More protein is found in the inner than outer membrane fractions.
Sequence:
MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL
The following text describes a protein:
Function:
Probably part of a binding-protein-dependent transport system YphDEF. Probably responsible for energy coupling to the transport system.
Sequence:
MFTATEAVPVAKVVAGNKRYPGVVALDNVNFTLNKGEVRALLGKNGAGKSTLIRMLTGSERPDSGDIWIGETRLEGDEATLTRRAAELGVRAVYQELSLVEGLTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAQKQLVEIARVMKGEPRVVILDEPTSSLASAEVELVISAVKKMSALGVAVIYVSHRMEEIRRIASCATVMRDGQVAGDVMLENTSTHHIVSLMLGRDHVDIAPVAPQEIVDQAVLEVRALRHKPKLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLEEYEQGEIVINGEKITRPDYGDMLKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISANGVLQWSTIRRLTEEVMQRMTVKAASSETPIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVRELAAEGKSVVFISSEVEELPLVCDRILLLQHGTFSQEFHAPVNVDELMSAILSVH
The following text describes a protein:
Function:
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSSPTVLELFDVCFKQEDVDSLKKPNWFTDVSIDYVDELIEHLWFPSYPNQANEILLLRPSLVFLLAEAAISPEELKVALPKKLMNCKYLFMPINDLDKHAAGSGGSHWSLMVASIPDGQCYYYDSLSNGKTKDCRSALARVSDLFKKKFTIECMPVQQQRNGYDCGAHVCAFTLELVRRLLHSPMPTSSMWNLSTFQPDVTAIREQLSRCLDHIINSLGTRVSGDFDEDFPTGTVFFDLESHLPLLDVALPVLPKSSDSSETSHESSNSNLKKSSESGSTNHHNNHESDKDLHHEGHHHHHHHHHHHHSHDDDPSSPAEKKQNHVPSPSEKIQDHVPSPSEKKQDRVPSPSNNKEDHLPLLSDEKLDKSAIDKIEPTPLPSVHMNSHIAKGELPKFHNSTDNPFLTPPEELVSGDFPF
The following text describes a protein:
Function:
Immunity protein that plays a role in preventing early activation of toxin VgrG3.
Sequence:
MNNLLSAYVTMLLILLSISGGAIASENCNDTSGVHQKILVCIQNEIAKSETQIRNNISSKSIDYGFPDDFYSKQRLAIHEKCMLYINVGGQRGELLMNQCELSMLQGLDIYIQQYIEDVDNS