lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB2 constitutes the catalytic core.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MEALDWMGPSVMNITTIAYDWVSTVFDAPLVSRAVVFGFPIDGHIVVEVLLIAVILFLLSRKSYKHPKKPLTEKEIDELCEDWQPEPLHPPITKEMLSQPRVLESAAGTHTTIEGRDIVNFSSANFLGLIGHEKLIDSCVVSLEKYGVGSCGPRGFYGTIDVHLDCEARIAKFLGTPDSILYSYGISTIFSVIPAFCKKGDIIVADEAVHWGVQNGLYLSRSTVVYFKHNNMASLESTLEKMTRGNRRAEKIRRYIVVEAIYQNSGQIAPLDEIAKLKEKYRFRLILDESNSFGVLGKSGRGLSEHFNVPVDKIDIITSSMGNALATDGGFCTGSVRVVDHQRLSSAGYVFSASLPPYLATAAIAAVDHLEQNPALLSKLRKNIGLLWKELSGITGLKISSSPLSPIVFLNLKNSSGSSKNDFKLFETIVDKVLKEDSVFVVASKRSVLDKCNLPLGIRVFVSAGHTKNDIFKAAESLKRIAETVLYDHCLNY
The following text describes a protein:
Function:
Required for intron-independent turnover and processing of mitochondrial RNA. It is a key control element in nuclear-mitochondrial interactions (By similarity).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MFLETLIHGVTFCVPFFSKSARIHTLSKDVFQQRKFPGNTLWAAALNRFTAYLFASKELSSKQAYLAQDFVNVCKDASVFQNVYYYELKKNILTDLGFSDLKNSDKSLALSKSSSTFDLQKIKKIHDCLLSEYRKYVRYQERIEETRPDLQKQLTDLKNPIEWYPGARKLRRHIIMHVGPTNSGKTHRALERLKTCKKGIFAGPLRLLAHEIYNRLQANGIACNLYTGEEIRNDYPFPQVVSCTVEMCNLSTTFDVAVIDEIQMMADPSRGYAWTQCLLGLQAKEIHLCGEESVVKLVRSIAKMTQDDFTVYRYERLNPLHVAEKSLNGKLSELKDGDCVVAFSRKNIFTLKSKIDQALGKKSAVIYGSLPPEVRNQQASLFNSKSSDENILLASDAIGMGLNLGVKRIVFSDLKKFSGVSTIDIPVPQIKQIAGRAGRHNPNGSKQSAGIVTTLYQKDFAKLNRAMNLPTKNLFNACIGAKDDLFFRYLSLFSDDIPQKLIFDRYFKLAKTTTPFVVSEGALSTFIIEYLDHIKGLTIKDKIKLLGCPVLKHSKYAPLFIREIGCVIAQGKRLQIYDLKSVPLEILERGIPTTETELQQLEQLHKLIVAYMWASIRYPAILQNGAAEKTKAIAEAFLIKGISKLQK
The following text describes a protein:
Function:
High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MALTPESPSSFPGLAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSAMGVVGVVGNAYTLVVTCRSLRAVASMYVYVVNLALADLLYLLSIPFIVATYVTKEWHFGDVGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLLTLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRRSQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYHQAPLAPRTARIVNYLTTCLTYGNSCANPFLYTLLTRNYRDHLRGRVRGPGSGGGRGPVPSLQPRARFQRCSGRSLSSCSPQPTDSLVLAPAAPARPAPEGPRAPA
The following text describes a protein:
Function:
Essential inner membrane component of the type IV pilus (T4P) that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility facilitated by cycles of extension, adhesion, and retraction of T4P fibers. Controls both pilus assembly and disassembly and plays an important role in PilB localization to the complex and ATPase activity.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLVKAHLRKQGINPLKVRKKGISLLGAGKKVKPMDIALFTRQMATMMGAGVPLLQSFDIIGEGFDNPNMRKLVDEIKQEVSSGNSLANSLRKKPQYFDELYCNLVDAGEQSGALENLLDRVATYKEKTESLKAKIRKAMTYPIAVIIVALIVSAILLIKVVPQFQSVFQGFGAELPAFTQMVVNLSEFLQEWWLAVIVGVGAIGFTFKELHKRSKKFRDTLDRTILKLPIFGGIVYKSAVARYARTLSTTFAAGVPLVDALDSVSGATGNIVFKNAVSKIKQDVSTGMQLNFSMRTTSVFPNMAIQMTAIGEESGSLDEMLSKVASYYEEEVDNAVDNLTTLMEPMIMAVLGVLVGGLIVAMYLPIFQLGNVVG
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MAPAVANLSISFKKSDNNNVNFLLAPVTDLYKDKKCVVIDLDETLVHSSFQPVKNADFIIPVEIDGTIHQYADPVTDLLDKWNVFQARLFRESCVFHRGNYVKDLSRLGRDLNRVVIIDNSPMSYLFHPKNAVPVMSWFDDPSDRELLNLIPFFENLATTRDSVYMFLNQSRQSAAFNSASLRTIEAVSLVTQQATLTNQQATFHPTSNEEIAPLNDTFSPAPVVVVIDDVDAVAAAAGFNVADSAEKVAVVCNGDAGSKECNDVIDGVRSHPLHKGDGDQQQQQPPPQQQQQMKLQQPQIKVQSAEQLKQQQQHHQERQQNKAILRQNHLQQQQHSLPQPALKVLFCCSNRNCSNDSNKNITTHNNKRAQQTINNKNFNGLHHSNNNNNSSSNNNNNSYIFHYINSLQIKYNNNNITLNSQQHQQLQHKRQHYRHVASLSAA
The following text describes a protein:
Function:
Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA.
Subcellular Localization:
Chromosome. Nucleus, nucleolus.
Sequence:
MQVLCKSEPWSSAKFFSIDTLKVKDRKKKKKKGQEAGGFFEDASQYDENLLFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTITAASFPTTLQRVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGKAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERKKEKIAKALQEFDLALRGKKKRKKFMKDAKKKGEMTAEERSQFEILKAQMFAERLAKRNRRAKRARAMPEEEPVRGPAKKQKQGKKSVFDEELTNTSKKALKQYRAGPSFEERKQLGLPHQRRGGNFKSKSRYKRRK
The following text describes a protein:
Function:
Protein phosphatase which antagonizes mitotic cyclin-dependent kinase cdc2, the inactivation of which is essential for exit from mitosis. To access its substrates, is released from nucleolar sequestration during mitosis. Plays an essential in coordinating the nuclear division cycle with cytokinesis through the cytokinesis checkpoint. Involved in chromosome segregation, where it is required for meiosis I spindle dissambly as well as for establishing two consecutive chromosome segregation phases. Allows damaged actomyosin rings to be maintained to facilitate completion of cell division in response to minor perturbation of the cell division machinery. Dephosphorylates the mitotic inducer cdc25 for its rapid degradation. Down-regulation of cdc25 activity ensures a prompt inactivation of mitotic cdc2 complexes to trigger cell division. Also dephosphorylates cdc2-phosphorylated nsk1, allowing nsk1-binding to kinetochores and spindle. Dephosphorylates ase1, which is essential for spindle midzone assembly and for continuous extension of the anaphase spindle. Tethered to the contractile ring by mid1, where it dephosphorylates cdc15.
Subcellular Localization:
Nucleus, nucleolus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Localizes to kinetochores in prometaphase. Cytoplasmic retention is mediated through the binding of rad24. Tethered to the contractile ring by mid1.
Sequence:
MDYQDDGLGEMIEFLEDKLYYTSLSQPPKAELYPHMHFFTIDDELIYNPFYHDFGPLNVSHLIRFAVIVHGIMGKHRQAKKSKAIVLYSSTDTRLRANAACLLACYMVLVQNWPPHLALAPLAQAEPPFLGFRDAGYAVSDYYITIQDCVYGLWRARESSILNIRNIDVHDYETYERVENGDFNWISPKFIAFASPIQAGWNHASTRPKKLPQPFAIVLDYFVANKVKLIVRLNGPLYDKKTFENVGIRHKEMYFEDGTVPELSLVKEFIDLTEEVEEDGVIAVHCKAGLGRTGCLIGAYLIYKHCFTANEVIAYMRIMRPGMVVGPQQHWLHINQVHFRAYFYEKAMGRAIQQATAAEPLATPPRHPLNATNGTSQSNISTPLPEPTPGQPRKVSGHNPPSARRLPSASSVKFNEKLKNASKQSIQNENKASYSSYEDSEIQNDDETRTVGTPTETISVVRLRRSSSQSNIEPNGVRSPTSSPTGSPIRRTSGNRWSSGSSHSKKSAQRSVSMSSLNNTSNGRVAKPKPSKSRLIS
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Sequence:
MAPHRRSSGGGSGGGGGAAAKQQRSIASFFSPGAPSPAAKKVLVINDATTAASNPAVTAPNEEGDDEKSKESPLKRPADDNVCGSPPAESSKSLKRLKQKVVLEDGDDEEFLEKMDLENSHCGKTRRSSSVSSASAAVKTSDGLGAPRKRLRKKYVVASSDDDSGCEVKGADVKEKRTMEDEATIGEIPKEDTRQRAEELEKITRFKEETVRQIEPATTRADECCEADRSLLLSGEALERFGGRISRKFSFLGKNRKDSSGRRHDWPNFDSRTLFLPAEFVKGLTGGQRQWWEFKAKHMDKVLLFKMGKFYEMFEMDAHVGAQDLDLQYMKGEQPHCGFPEKNYFENVEKLVRKGHRVLVVEQTETPEQLEERKRKTGSKDKVVRREICAIITKGTMVDSGMISDNAEPSFLAAVTEKADNYGSSLVGLCVVDASRALFMLGQVEDDSARTKLRSILTELRPVELVLPLGLLTDATQKALREQTRKPLISQLVPSKEFWDAEQTTKEIRTSYGASDAMPTVLQKILELGVSSEPVLSAFGGCICYLRQSLLDGQLLQLGRFELLPGSDLSFEHSAAIPEADPAEAHMVLDSAALDNLEILENSSNCGVAGTLLCLLDHCITPFGRRLLKQWIVRPLCNIESIVQRQNAVVDMQGVAENAVSEFRRELFGIPDLERLLARLSANSGENGRHSQKVVLYEDAAKKQIKELVAALRGFQKLVKAVSCFGNCLPQLKSARLRSLLTFGKGFPDLKPLLQYFEDSFDWSESEANGRVTGGDHSNLSASDPREKLESYLKSQQKFFKNPEISYVTVGKDTYLLEIPEELHTKVPSDYELRSSRKGFCRYWTPRVKELLQELSLCENEKEAALRGILQTLTKRFCDDHDHWLSAIRAVSELDALMSISSARLHMDGMTCLPTFVPASQLAKPVFRAKALRHPIVAVSTAASTPFVPNDVVLGGGSNPEVMLLTGPNMGGKSTLLRQVCLGMILAQIGSEVPAESLELSLTDRLFVRMGAKDQIMTGQSTFLIELLETAVMLRCATQNSFVALDELGRGTATSDGQAIAHAVLHYLAHNVQCRGMFSSHYHKLASDFANDPSVSLCHMACKVGGGNNELEAVTFLYKLTSGSCPKSYGVNVARIAGKRKFPSHAHRACCAEPYYSLPNSRKKWNLTVTKRTSSKPSSMPLLTVRNNFARLGRRQNLYKHEAGFATGFGRPSFEELRYGQGSIENRFLQGF
The following text describes a protein:
Function:
Catalyzes the first step in phosphatidylcholine biosynthesis. May contribute to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine but the activity is much higher with choline.
Sequence:
MSSRKVSRAHYDEDELASAANMSLVAEGHFRGMKELLSTMDLDTDANTIPELKERAHMLCARFLGGAWKTVPLEHLRISRIKGGMSNMLFLCRLSEVYPPIRNEPNKVLLRVYFNPETESHLVAESVIFTLLSERHLGPKLYGIFSGGRLEEYIPSRPLSCHEISLAHMSTKIAKRVAKVHQLEVPIWKEPDYLCEALQRWLKQLTGTVDAEHRFDLPEECGVSSVNCLDLARELEFLRAHISLSKSPVTFCHNDLQEGNILLPKASSGNIRMPSLSDETQALGNSLSAFNPADPRLVLIDFEYASYNYRAFDFANHFIEWTIDYDIDEAPFYKIQTENFPENDQMLEFFLNYLREQGNTRENELYKKSEDLVQETLPFVPVSHFFWGVWGLLQVELSPVGFGFADYGRDRLSLYFKHKQLLKNLASHQ
The following text describes a protein:
Function:
An essential component of the GATOR subcomplex GATOR1 which functions as an inhibitor of the amino acid-sensing branch of the TORC1 signaling pathway. The two GATOR subcomplexes, GATOR1 and GATOR2, regulate the TORC1 pathway in order to mediate metabolic homeostasis, female gametogenesis and the response to amino acid limitation and complete starvation. The function of GATOR1 in negatively regulating the TORC1 pathway is essential for maintaining baseline levels of TORC1 activity under nutrient rich conditions, and for promoting survival during amino acid or complete starvation by inhibiting TORC1-dependent cell growth and promoting catabolic metabolism and autophagy. In addition, this inhibition of TORC1 is necessary to maintain female fertility under normal conditions and during periods of nutrient stress. GATOR1 and GATOR2 act at different stages of oogenesis to regulate TORC1 in order to control meiotic entry and promote oocyte growth and development. After exactly four mitotic cyst divisions, the GATOR1 complex members (Iml1, Nprl2 and Nprl3) down-regulate TORC1 to slow cellular metabolism and promote the mitotic/meiotic transition. At later stages of oogenesis, the mio and Nup44A components of the GATOR2 complex inhibit GATOR1 and thus activate TORC1 to promote meiotic progression, and drive oocyte growth and development.
Subcellular Localization:
Cytoplasm. Lysosome. Note=Localizes primarily to the autolysosomes during amino-acid starvation.
Sequence:
METNVNPLAVILVYFDSKGDRLLYRYPYQTLGQTEVANDEQRKSRKRNPYAVANTDDLLQTPTHLGAAKSQGQLQGFADEVLSALFAVKPQLCNQKFELKLNDVRFVSHPTLIPQKEQRSGPMAKQQMLINIVFALHAQASYSIVKCYHELSKRLGLALKFEEQRSGYLTEQTAQMARTHDEQQQQPLERTLELIAERCSLAQALRSIFHDLCTTGLLSTSLNHNLTLCFCLPAKAHQLHKKGSMVDPETIDRCLRALKPYHGMLLLVDFAELLDCVPPTGARMLWQLVDVYDPLISLQSMSSNADLSIEHVYKLVSHLVYWAKATIIYPLCETNVYVIAPDAPLHTKSHLVEKFSARFAGMSLFEVISDFSLPTSIGHLTTPLQQPARQGILAQMVIWMLQHHLLMQLHTYVQFMPSEDEFGDSASCSNHLRDAISDEEGDQEPDADELHGSMLSMSSHPLPVPAVLVGGHRREASEDHSSLASDNIAVQPSSSHKSNFSITASMSTDNCDSLDSMEDEQKLKELLQVFSDADRAAIRRIPASANVDDLSLLVKLYQMGYFKSEHHLEEIMYFENLRRSQLLQLLDKFRDVLIIYETEDPAIASMYNTK
The following text describes a protein:
Function:
Trans-acting factors of the ribosome biogenesis process.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MDSKEYLISYGWKEGEAFREGGLKRPILVKHKRDKKGLGNAPGGNDGEAWWERLFDGHLKNLDVSTDSNNGSIKFTQNEAVATAVSKSSSPLYRWFVKGEGLKGTITNLGKKEEASFVVSSASSSKGKKRRRRDEDDNKVKRKKLKKDKKTSNDSESKKKKKKKSKKESKKGKKSKHSSDEGDKSKHKKSKKSKKHKKEESSARRDRKEHI
The following text describes a protein:
Function:
Matrix protein of the sea urchin embryo spicule. The function of the matrix proteins is to direct crystal growth in certain orientations and inhibit growth in others (By similarity).
Sequence:
MRGFVYVLVCVLALASFSRAQLPGGGGPVLPGGGPTIGPVNPDPTRTEVCAKFWVQEGNSCYLFDSGAFLRQVAASRPVVVNNENGLFQAAANMYCGQMHPNASLVTVNSLAENNFLYEWAVRMMVEPEPVWIGLHAGPMGQWQWYSGEPVTYTNWERMTAPMAEPGLGAMIFDADIIAQMFNNQVEITPQWVPEQAINDRHALICEYHPSGMTAAAAAATNAPTFPPMATAPPMAATTRGPVMFQNNPRNLVNSLTGGRFGGSLLHEIPRRQRMRPSNYRKNPYFGIQP
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MVSLARTIRHFRLVGFKEWFRQLTYIGDAKYGRLVGTDQFGNRYFEQLDPKEELPGRHRWIDYSQDDFNASQVTPEWHSWIHHIRKDAPTDDVIMKQLSPPWKAPYTENMTGTRGHFKTYSTTAPKIQAWDPVVKPRGGAQTQA
The following text describes a protein:
Function:
Functions as a component of microRNA (miRNA) and small interfering RNA (siRNA) biogenesis. May assist Dicer-like (DCL) proteins to efficiently process and/or recruit the precursors of miRNAs and siRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MGVDSDDEDLVVYGTPIEREEDTSARKRRAVAEAGQLRALPAWKQEVRDEEGRRRFHGAFTGGFSAGFYNTVGSKEGWTPQTFTSSRKNRAELTKQSIYNFLDEEDIKDMGGNALETSQQYDTFGFTAAEHARKQASKEQKERPSAIPGPIPDELVVPTKNSIGVTLLMKMGWRQGRSVRDSHADSLYESRRNARKAFLALSGAKDDEDQDQSAENSSLDKAVVGSVEEIPVSGNTPVYVLHPKEDFHGLGYDPFKHAPEFRDRKTLQKSKERDHKRNDASMRGNLLISNSGHYAPGFGIGALEELDAEDEDIYASGFAYERTEVDIEPSKAASDSNYKLDDRKRGFYLNFKIASNSEYKLERFLPPEIPDAFDAQHKFPTPVQSTEKFSDSAPLEVPPPEDTSLTLLIDGCAAMVARCGKHIEDFYKEKSKTNPQFLFLSGGDGCDYYMRKLWEHQQKHIGQQRHDSAKSKTSSDKLTAENRGKILGERPLDRTTKLHSPSLSAKDAVQLQSNLIDTFVKPISLDGLPESEKPFSNDLAKQVRFEQFLRDKYKGGLRAANVTPTSTMSEADRARERLDFEAAAEAIEKGKGKKVIDPSSVFSLPGMNEQRFVAATQPESSVVIQDEKPIYPQREQFEWRPSPILCKRFDIVDPFMGKPMPVRRPRSKMENLIFMTESNKGTKDEVESSSRSSQHASMEGVADVESQGATNDTDFEPSSLQRPVDLYKAIFSDDSGDDVDEILSNQPVDPVKTSEGANMALNRLVAEDFLESLGKELGLEVPPERPHVSSQPEKHLAAGASLPSQDERITTVLTKVKENQSYIGMVQVGNINEDIPLASAETLGMKYEKQENRTEKNRSLPMHRQSQNHSPRSDSSSERHRSWKRRSHHHIRNGTPESESSGERHRSRRRKKSHSRHRKGRSRSPDSDSPSDTQRERKRKEKRHRRTYTSDTDSSDHEHMERHKSSSRRSSDKDRSRKHPIHHKHRRRDHVNYS
The following text describes a protein:
Function:
Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSFRGGRGRGGGGSFRGRVVGSYIQPCEGDLVCKLENRNIPYFNAMIYLENKSEVGKVEDVFGTITDVHFTIKLSPGIKADGFNSDSKFYIDPFKLLPMDKFLPQPGGAKSRGRGRGRGGGRGGPMKRGGFGGRGGSFGGGRGGSFGGGRGGRGGSFGGRGGGGFGGRGGGSFRGRGGGGFRGGR
The following text describes a protein:
Function:
Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule. Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
Sequence:
MGVALRKLTQWTAAGHGTGILEITPLNEAILKEIIVFVESFIYKHPQEAKFVFVEPLEWNTSLAPSAFESGYVVSETTVKSEEVDKNGQPLLFLSVPQIKIRSFGQLSRLLLIAKTGKLKEAQACVEANRDPIVKILGSDYNTMKENSIALNILGKITRDDDPESEIKMKIAMLLKQLDLHLLNHSLKHISLEISLSPMTVKKDIELLKRFSGKGNQTVLESIEYTSDYEFSNGCRAPPWRQIRGEICYVLVKPHDGETLCITCSAGGVFLNGGKTDDEGDVNYERKGSIYKNLVTFLREKSPKFSENMSKLGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWRNQMTKRWEPSLNWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESEEDEEPPDHRQEASADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATEKARYT
The following text describes a protein:
Function:
Involved in the transport of the quorum-sensing signal autoinducer 2 (AI-2). Controls the transport of AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MAKPIITLNGLKIVIMLGMLVIILCGIRFAAEIIVPFILALFIAVILNPLVQHMVRWRVPRVLAVSILMTIIVMAMVLLLAYLGSALNELTRTLPQYRNSIMTPLQALEPLLQRVGIDVSVDQLAHYIDPNAAMTLLTNLLTQLSNAMSSIFLLLLTVLFMLLEVPQLPGKFQQMMARPVEGMAAIQRAIDSVSHYLVLKTAISIITGLVAWAMLAALDVRFAFVWGLLAFALNYIPNIGSVLAAIPPIAQVLVFNGFYEALLVLAGYLLINLVFGNILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIVKIALEQTAGGQSIAVLLSDLNKE
The following text describes a protein:
Function:
Glycosyltransferase involved in the maintenance of the outermost surface of the fungal cell wall. Likely functions in the synthesis of a currently unknown, potentially minor but widespread, extracellular or outer cell wall polysaccharide which plays a key role in facilitating many interactions between plants and fungi by enabling hyphal growth on solid matrices.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Secreted, cell wall.
Sequence:
MSESEHQNVGRSPLGFAGPLSLSMPSFDFWYSSTFWLYLFLGLWFHRYFRLLVHCVSHWTYKSKPIPSKPTFTSKDVTVVIPTIHNAFEELRPSLESILACEPAELILVTTHDKRKELQKLADSLVFPKVRVLDTPIANKRLQVCEALPKVETPITIMADDDVTWPSTLMPWILAPFEDPEIGGVGTCQRVRREHDGSWSTKAWNWLGAAYIERRNFEISATHNIDGGTSCMSGRTGAYRSEILSSHDFLHGFKNEKWRKWILNADDDNFVTRWLVSHQWKTWIQYEKECEIETTLENSTKFLYQCSRWARSNWRSNWTSMVTERYIWKQQLWCTYALHFATFTSLAFLIDPLLLASCWWGTADWDMQNRRYAFWSQFVFMFAFTKVVKLMGLFIRNPTDVMFLPVSVVFGYFHGLVKLYALITLNMTSWGSRADGDANDEQRLAPAPQPSIVLKTPPGKGSLIRYNARQKGRQTQAQQVSWEKSDYASYDSSTSYVPIRVHTPMATTPIDTKLYTNESSNTCWAI
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MSSYFVNSLLTKYQPGESLSSSNGFAGVPSCSYGELASTARGGYHAGAYGPYPATNSGPRDFYNGGAAGGYGSPNAHYQESPPVSSYCRGSAESASPPQSMSAMHGAACSYQQAEVRKDMAGVGGHPGHPVQQANPALNTAQMTTPIYPWMRSTAPERKRGRQTYTRYQTLELEKEFHFNKYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKLESLKQQPAESETSSTTS
The following text describes a protein:
Function:
Part of the ABC transporter complex MolBCA involved in molybdate import. Responsible for energy coupling to the transport system. Functions as a low-affinity molybdate transporter.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Domain:
The transition from the outward-facing to the inward-facing conformation is realized through the asymmetric motion of individual subunits of the transporter. Nucleotide binding is coupled to a conformational shift at the periplasmic gate. This shift is akin to unlocking a swinging door: allowing just enough space for molybdate to slip into the cell. The lower cytoplasmic gate, identified as gate I, remains open throughout the MolBC-A mechanism, and cytoplasmic gate II closes in the presence of nucleotide.
Sequence:
MNKALSVENLGFYYQAENFLFQQLNFDLNKGDILAVLGQNGCGKSTLLDLLLGIHRPIQGKIEVYQSIGFVPQFFSSPFAYSVLDIVLMGRSTHINTFAKPKSHDYQVAMQALDYLNLTHLAKREFTSLSGGQRQLILIARAIASECKLILLDEPTSALDLANQDIVLSLLIDLAQSQNMTVVFTTHQPNQVVAIANKTLLLNKQNFKFGETRNILTSENLTALFHLPMFEQQAQYKESFFTHFVPLYKTLLK
The following text describes a protein:
Function:
E3 ubiquitin ligase that acts as a key regulator of DNA repair in response to replication stress. Acts by mediating ubiquitination of the CMG helicase complex, promoting the unloading of the CMG helicase complex by the p97 ATPase (cdc-48.1 or cdc-48.2).
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MTSQPTSSLQGSCSICFEDLKQNDKISAIVCGHIYHHGCISQWIATKRQCPSCRRTVPKNGFVEKLFFDVQRMGGEAEKPPEIDYREEHYKLSTSLKVEQEKLGTLNTENKNLKDTVKSLEKKIIREKDKYRQEIPKLQATINHLTISSEETAYLKRELQESKNRLKTCEFYKILTVHSSEADKQLGEYLKKNGNLDTEKFFQLMKSTNKDLTDKRREAAKEIEQLKMEVQSLKRAAQEDAAIKKTLKKTVLDLRERANVDTPINNKRLRDVLETETPPPAKRKSMGFDESSQMIDPDGELSFFKQNENRTPVTSVPSTSKAVLPFNFDDDEDDEYFKTPKIAEKKKKLPEAMAPVSEDSFDFDIAVPQSIINRIPAKTTAQPAKKYPKIPNLSAKTSSKPTEAPKTENVLKIKSKSQEIAQKPQKSTRISSFFSRTTSSTSNLTEYVILD
The following text describes a protein:
Function:
May be signaling molecules that resemble neuropeptides.
Subcellular Localization:
Secreted.
Sequence:
MRRSRTADRRGDAPQRGMKTTCLWAAAGLLSLISLTCSAESQSFGNSHLRPKSKLKSYWTTSSKAVSISRLLAQNLYSKENFTSLDLSYDPTDSYSKHEQWSWLSNTSAARDPRSRTKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVGLVPPTKAVEFQIHQQHQQFHHFHQQQQQQQQTALETKDTKLFNCRVEYEKVEKGTKNSLCAHDPSQSCPQEQTQSHVSWLCSKPFKVICIFITFYSTDYKLVQKERNGAGSSKQHLHNENIPM
The following text describes a protein:
Function:
Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
Subcellular Localization:
Nucleus.
Sequence:
MGTGYRTQALYIGSTPDPARRLAQHNGLCKGGARRTADEKRRPWEMVMVVEGFMSKIAALQFEWAWQHPAATRHLTADAPSKEQSKTHEGIEDDDAVKKPQQKTKGLTDSRATGEREDDGKKKTKRKPPARRTRTSLKAHLEDLHLLLRSTYFKEWPLSLRFFAADVSQQWRWLCGRVNESIPTHIKMVADGNCADTSPQCDHSLGVGSVREIGVDYTPIRDYLEKATFLLDDMRGSYCKICKEQYVDNDWAVVCPEADCTSTTHLLCLSRTFLDATEDPERLVPLTGKCPTCAQTVQWPLMMKELSIRTRGGRLLHNMLKKGGKRTRTIQKAQDATAESDDNASAADIAVDASHEDSDDTDSLIDYWDRILGSDSESGASIHSQYGSKASGTEVNIEKNVFLDNGLLD
The following text describes a protein:
Function:
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MAVVAAAAATGSTTRSGGGGGEGTRSGRKKPPPPPLQERVPLGRRAAWAWRLAGLAVLLLLLALLALRLLRHHGGAGGDGGVWRVALVCEAWFAALCALNVSAKWSPVRFVTRPENLVAEGRTPSTTAAEYGELPAVDMLVTTADPALEPPLVTVNTVLSLLALDYPRAGERLACYVSDDGCSPLTCHALREAAGFAAAWVPFCRRYGVAVRAPFRYFSSSSSPESGGPADRKFLDDWTFMKDEYDKLVRRIKNTDERSLLRHGGGEFFAEFLNVERRNHPTIVKTRVSAVMTNAPIMLNMDCDMFVNNPQAVLHAMCLLLGFDDEASSGFVQAPQRFYDALKDDPFGNQMECFFKRFISGVQGVQGAFYAGTGCFHRRKAVYGVPPNFNGAEREDTIGSSSYKELHTRFGNSEELNESARNIIWDLSSKPMVDISSRIEVAKAVSACNYDIGTCWGQEVGWVYGSLTEDILTGQRIHAMGWRSVLMVTEPPAFMGSAPIGGPACLTQFKRWATGQSEIIISRNNPILATMFKRLKFRQCLAYLIVLGWPLRAPFELCYGLLGPYCILTNQSFLPKASEDGFSVPLALFISYNTYNFMEYMACGLSARAWWNNHRMQRIISVSAWTLAFLTVLLKSLGLSETVFEVTGKDKSMSDDDDNTDGADPGRFTFDSLPVFIPVTALAMLNIVAVTVGACRVAFGTAEGVPCAPGIGEFMCCGWLVLCFFPFVRGIVWGKGSYGIPWSVKLKASLLVAMFVTFCKRN
The following text describes a protein:
Function:
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules. Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Localizes at the cell poles through interaction with FimV where it increases the local pools of c-di-GMP (By similarity).
Subcellular Localization:
Cell inner membrane. Note=Localizes at the cell poles in a FimV-dependent manner.
Domain:
The GGEEF domain is required for function.
Sequence:
MSRDDVQRWKDKYLENIEQQERLQRRWDARIDLLRRGLVRSSLAAEGSDKAVDQCMKELREILRRDDMDAGLSGLIPRLEKAVLDSEQRRQQRTQQNIDALGELAQQLLALDLPRELRKPLKQFARDIEERARQSREIPILLSELSRLQRQALAERKGGDAEDGRPSLLQRLFGGKESETTAEPSASVPSVVAASNTPIQPAAAAPSLPVAEHDEAPGGPPQPLPARTVAAIESAPAGWVGVAERGEPNQILLDEPREIWLDSLPLPAGLSFSETLEEAGAEPSPAMPADVESAPEAPATPVDNLDGQAVDEAYELPPPIPEPGYSAVAPHIEASLLRLLDGLSLPSSHQPQAEALRERIDGSLNWYELVPVLDDLAVLVLSLADSGQRDFEEYLRQLNERLESFLGHLGDAHAGYTDVLDNARGFDQSLREQVSGLQASVQQATDLNSLKLAVDSRLNGLLASMDEHQREQAEHEQEVSGRLQALMERVNSMEQDAKAFHSHLEDQRQKALTDPLTGLPNRAALSERLEQEVARRHRDGGDLLLAVLDIDHFKRINDDFGHLAGDKVLKIIAGELRKRLRQADFIARFGGEEFVVLLPATSLEAGRQLLERLRAAIAACPFHFKGEPLSITCSAGITAFEGNEAGEAVFERADQALYRAKRAGRDRLEVA
The following text describes a protein:
Function:
Catalyzes Na(+)/Ca(2+) exchange. The transport is electrogenic with a likely stoichiometry of 3 or more Na(+) for each Ca(2+). Is K(+)-independent.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MITVNFLILLLGLVFLVKGSDYFVKSASTIAKKLGVSEFVIGLTLVAIGTSIPELASSIAASIQQASGIVIGNVVGSNIANVGLIVGVAALLSPMKTEIDMLKRDGYIMLFSAVLFFVFAFNRELSMLEAGLFVLLYIAYVFFLFEEAEKYEGKLHFKEFITYFFKFKYINSAMQKLNGNRNRNSDSDRNSDSGNGNERLEGGFAKDIFTLVLSCAAIVIGAKYFVEESIFFAELLGIPDTVIGTTLVAVGTSLPELVVTVSAARQGYGSIALGNVIGSNITNIFLILGLSGLFYPLSVAEMSLFFTTPVMIAISLILLIFISTGWEIKRWEGVVLMMFYVAFLVVLFYI