lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane.
Subcellular Localization:
Cell outer membrane.
Sequence:
MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSVHSIAWQNNNIARQEAEQARAQANLPLENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDNKTALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTTLGSDLSVATATTHVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQADGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERRELVVFITPRLVSSE
The following text describes a protein:
Function:
Interacts with host ephrinB2/EFNB2 or ephrin B3/EFNB3 to provide virion attachment to target cell. This attachment induces virion internalization predominantly through clathrin-mediated endocytosis.
Subcellular Localization:
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Domain:
The N-terminus four-helix bundle form the stalk and the C-terminus form the receptor binding globular head domain.
Sequence:
MPAENKKVRFENTTSDKGKIPSKVIKSYYGTMDIKKINEGLLDSKILSAFNTVIALLGSIVIIVMNIMIIQNYTRSTDNQAVIKDALQGIQQQIKGLADKIGTEIGPKVSLIDTSSTITIPANIGLLGSKISQSTASINENVNEKCKFTLPPLKIHECNISCPNPLPFREYRPQTEGVSNLVGLPNNICLQKTSNQILKPKLISYTLPVVGQSGTCITDPLLAMDEGYFAYSHLERIGSCSRGVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVYHCSAVYNNEFYYVLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRSIEKGRYDKVMPYGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQYSKPENCRLSMGIRPNSHYILRSGLLKYNLSDGENPKVVFIEISDQRLSIGSPSKIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPGQSQCPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTVFKDNEILYRAQLASEDTNAQKTITNCFLLKNKIWCISLVEIYDTGDNVIRPKLFAVKIPEQCT
The following text describes a protein:
Function:
Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MANPFVRNQSFKSVFFKNLVGITLWVPVLMFVEQHVVSVGTIEGRSMKPAFNPETNMLQRDRVLLWKWNKDYKRGDVVILRSPENPEELLVKRVLGVEYDIMKTRPPKKLSLVPVPEGHVWVEGDEQFHSIDSNKFGPVSTGLITAKVIAILFPFSRAGRIDHEGFRKNAVFLSGKRSVK
The following text describes a protein:
Function:
Specifically methylates the adenine in position 2030 of 23S rRNA.
Sequence:
MNYRHAYHAGNHADVFKHLVLARIFALLGRKDTPYAYLDSHSGVGLYDLQGDEASRTGEWEQGIARLWEREGLPEQLDDYLDVIRHLNPDGSLRYYPGSPELARRLTRAQDRVLLNELHPEDGRLLKANMAGERRVAVHQGDGWLLPRAFLPAPEKRAVLLIDPPFEQADELQRCVAALDEAIGRMRQTVVVIWYPIKDQRQLKRFYQALERSVAPKLLRAELHVHPIDDAERFNGSGLAIVNPPWPLEDELRDLLPWLAEVMAQSQGGWRLDWLVAE
The following text describes a protein:
Function:
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine. Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate. Also has adenosine deaminase activity.
Sequence:
MNFEKINVGAYTFLKSEFKNANFIFSTGENHLNFNKNIDEGKENLNNIKKWFLLEEVCYLDQVHSSIVRNFKDKDKEGDAIITNKFNRAVGVFTADCVPILLYDKENEAIGAVHSGWRGTYENIVINTLKKMKENYNTKTENIIASIGPHIKDCCYEVSYELINKFKEDKIYNDYNINYKRNLNMEACILAQLSNVGVKNKNIIRANLCTMCSSDPKFYSYRKEGNIGRQFSFVYLNKQ
The following text describes a protein:
Function:
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MAREDMDRGSSWIKETEGGSQTSGPSKGADMQVSVTLDEQQPLVGGQRADEEVLARWRGRWVFPAWLLVCFSTGPTYVMMRSFVPASLQTIAHELGHPKGHPAAHCRPRGDDCYIYVGGRDVQFTAYVLYMRALYTSIEGLIAIVLMGLADFSNYRKWLMTLSIVMYGALATPFVSQGSKTYGALILMSVLYCLMLCCNTIYTITEGSYIPVFMDMARLAAARDAASAKLGDGVEERTAGEPVNPMLRRGAKVSVLGLIMGNLGSIVAVLVGIIITYSRGKPQAEGYSAFLLTITIAGCATIVLGSVASLGIPAIHGSRFPFDPQENKLITICKFPFRRFMYILRDLTHYREAFKYVVAWVLWNIAYSNFMQLFQLSFRATLGSTADKEYFVWQLMTSVIACVGSLTWMAVFRHFSARRTLRAQTQLLKTCLYAMMAVGVVVNFWGSLGASSRVPIGFKHRWEFWFFQVIYVSTSSAIRSLNRVAYSAMLPAGRENQYFGLEIMLGLATGWSQSLLVSVIQDRTGNARFPYIPNTLLLIVSLGFYYWSDLSHGMLAAGKAELHRAAPQDAS
The following text describes a protein:
Function:
Probably part of the ABC transporter DppBCDE involved in dipeptide transport (Probable). Responsible for the translocation of the substrate across the membrane (Probable).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MARYMIKRFWAMAATILVITTLTFVLMKVIPGSPFNEERGTNEAVQKNLEAYYHLDDPLIFQYIFYLKSIITFDFGPSIKKPSDSVNDMLERGFPVSFELGMTAIVIAVISGLVLGVIAALRRNGFLDYAAMSLAVLGISIPNFILATLLIQQFAVNLKLFPAATWTSPIHMVLPTAALAVGPMAIIARLTRSSMVEVLTQDYIRTAKAKGLSPFKIIVKHALRNALMPVITVLGTLVASILTGSFVIEKIFAIPGMGKYFVESINQRDYPVIMGTTVFYSVILIIMLFLVDLAYGLLDPRIKLHKKG
The following text describes a protein:
Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MNKLRAEQLKQTMDRIHRIEGHTNVSGVLVINTKGLILHTSLDTTQTTAYTQQCVPLVELARATIRDTDPEDDLRFFRVRTLKHELIIAPEDKYTLIVIQKTDAQANRFIL
The following text describes a protein:
Function:
Intercellular signal essential for a variety of patterning events during development.
Subcellular Localization:
[Warthog protein 6]: Secreted. Cell surface. Note=Also secreted in either cleaved or uncleaved form to mediate signaling to other cells; [Warthog protein 6 N-product]: Cell membrane; Peripheral membrane protein; Extracellular side; [Warthog protein 6 C-product]: Secreted, extracellular space. Note=Also secreted in either cleaved or uncleaved form to mediate signaling to other cells.
Sequence:
MTLLNLFYCFCLLFGAVLADSIHDGGSCGTNSIPYKMEVDSEGKPVISCEAPSCLGVSSSAARRPRVLDVSCDPFKEIVCVKDLQWTSGLVEINNGTHRTLKTECCSYEGMSDAKTIKSIFLGPGQSFVGGMVEKDGEQSGFDLIKEIRKTVNADNQVQYIVGVYRMPCEATSDSSEEALPLLSRNRRKLRDRVGKYDDYEEDRNYRSERRRPFAMRRRALLQRLEDMYDDYDYEFRVVRRPFRKSRLPYNENALWPLQYSSPQRSRTFADNTYNKETVESGPLPPPPSSNYIDNVAPASPVVQSPAYPQTPAEMPLPPQSGSYSGSYSGYPTADASQYNAYPAMQQPAYQPAYQPAYQPAYQPAYQPAYQPAYSARGYSPNLNGLFGGTGMQCFSGDMEVETEDGIKMIKDLKIGDKVLSMDEAFVTYSPVIMFLHKRDEEIAEFNLIETANGHSIKLTDNHLIYVSDCRTRSDLKLVAAKEVKMDDCIHVTTDSNVVIKKKVSKISKVIETGIYSPLTSTGDIIVNRVLASCHSNLALKSLQQTFFSLYKRTSSVFHNLMFFKSSTEEGDLPVGVETLTSVMDLFIPQSFV
The following text describes a protein:
Function:
Probably involved in the defense reaction of plants against pathogens.
Sequence:
MMLCKLPLALCFLISTALTILSYAQDTHQDYLNIQNQARADVGVEPLTWDDKVAAYAQNYANQRIIDCNLVHSEGPYGENLAWGGGDLSAIDAAKMWVDEKPYYDYDSNSCAPGQVCGHYTQVVWKNSTRVGCAKVTCNSGGTFIGCNYDPPGNYIGERPY
The following text describes a protein:
Function:
Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
Subcellular Localization:
Nucleus.
Sequence:
MLKTSSTSNDNGSSITKVSECNVVDESPSSQRQREGQQPPPTEQSTADGGEICYDLAHFRTVRVLNNNSTHKCVALLGRFSNLSPDQQAIVVLEKRAFTEAEITTTPAEREKSAQHGESETEKSEQQPSSEQGRTFFTTSSRLHKEFVNDVYGNFLCTVDPELNRLKVSIIYPASEKHIVKHTAQHRYMIEETIDQYNKITLPHLEEEQLSLEWLYNVLEHRKEKERILYEDPCDENGFILLPDLKWDGKTVEQLYLLALVRRRGIRSLRDLTAADLPLLRNVQTRGIAAIEKRYGIGASQLRIYLHYQPTFYHLHMHFTYLRYDPPGAGCEKAHLLSTVINNLELAGDYYQRATLSYTLKETDKLYGKFLLAQEAADEPVAKRSKTTVLDESQ
The following text describes a protein:
Function:
RNA-binding protein involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MDCTFTERLLRAKLCWRLQNSLLDLGSSSASACLVVRAQTGPLASLGLDLPFSRAESLHSPGGKRSAARVPGGGRRRPRQSEAQRSHGPHGQASLPAASVKPSEAPKELVIPLIQNGHRRQPLTQAPGPSTDTEALADGMLSQAVKELIEESKKSLEERENAGVDPTLAIPMIQKGCTPSGEGADSERWAETVPEEADYEAVPVEAYGLALLRGMGWKPGEGIGRTFNQVVKPRVNSLRPKGLGLGANLTEVQALAPTGPHRLPRPDEEQEKDKEDQPQGLVPGGAVVVRSGPHRGLYGKVEGLDPDNVRAMVRLAVGSRVVTLSEYYLQPVSQQEFDKNSMELSQRNRSSPGQQNGTASSWKALRDQDLHIRQEDSERKRKHLPDRQDGPAAKSEKAAPRSQHWLHRDLRVRFVDKLHKGGQYYNTKMTIEDVLSPSTCVCRTDEGQVLEGLREDMLETLVPKIEGNRVMVVLGPKAGRVGRLLGRDGERSRALVQLRRENRLVELHYDAVCQYVGPSDSEED
The following text describes a protein:
Function:
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MILLEINNKIVEDTLTVKIKNSLAGNKPDSVNVVIADFDGVLFHIANPDSDKSKVRVSISLKFYKDLQEHGADELLKREYGNLLCQAEDGYNISLVLDLDNIPGNWEEIVKKIGLLKRNCFASVFEKYFEFQEKGEEGHKRAVINYRDEETLYIEAKADRVTVVFSTVFRDEDDIVLGKVFLQELREGRRASHTAPQVLFSHREPPLELQSTNAKIGDNIGYITFVLFPRHTNKNVRENTINLIHLFRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEPKTVEKKTITGRTFIRTP
The following text describes a protein:
Function:
Essential for tRNA splicing and maturation. Acts by directly joining spliced tRNA halves to mature-sized tRNAs. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends.
Miscellaneous:
MISCELLANEOUS: Ligation proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RtcB reacts with GTP to form a covalent RtcB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.
Sequence:
MAPKSMLKHIRNNVVWELPEDYKGCMKVPGRIYATEKLIDGMEKGVFDQVANVACLPGIYGYSIALPDAHYGYGFPIGGVAAFDVEEGVVSPGGVGYDINCLAPGTKILTEHGCWVKVEDLPKMLTDQKLKVYDVDEGREDDSEIKFVMERGIEEDERAVVLVTESGLTIEGSEDHPVLTPEGYVELGEIEEGDLVVVYPFEGVEYEEKEGTILDESDFEDVDPQVLRYLEERDLIPLRWSDPKVGTLARILGFAMGDGHLGEQAGRLTLSFYGDERTLRELKRDLESLGVKANLHVRKRRYEIETASGRYEGEATSVELRVASRSFALLMEKLGMPRGRKVETPYKVPDWIKEAPLWVKRNFLAGLFAADGSVVKFKRYTPLPINLTQAKVEELEENLREFMNDVAKLLREFGIETTLYEVKSKKNVVYKLAIVGEENIKRFLGKVGYEYDPEKKVEGLAAYAYLKLKERVKKDRKEAAETAAEVYEETGSITKAHEAVADVVNRRFVERVVYDGGISSVRVPEDFPTFERFKEERVLAGGFVIEEVVEVKGVEPEYDRFYDIGVCHGAHNFIADGVVVHNCGVRVMKTDLTEDDVRPKLRELLETIFRNVPAGLGSRHRRVRLSTQELRQVMLYGAEWAVEEGFGFDEDLDHIESRGNMTHAYETIGWEEYGPRDDVASKRAIERGRPQLGTLGSGNHFLEVQVVDEIYDKEAAEKMGIREEGQVTIMVHTGSRGFGHQVCSDHLRIMERSMRDVERRFGVRIPDRQLACAAMGTDEAKRYFNAMNAAANYAFANRQMISHWTRESFVEVFGDEYGDADDMGIEVIYDIAHNMAKIEKHPVDGEERWLVVHRKGATRAFSEEALKKHGEPVPFEGLPQPVLIPGDMGTGSYILIGTEKAMEETWGSTCHGAGRTMSRAAAKRKFWGEDVARELERQGILVKAASMPVVAEEAPPAYKDVDEVVRAVAEAGISDPVVRLRPIGVVKG
The following text describes a protein:
Function:
Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MDFENDQLYNWLQLANLESFYPNFIKKNVSCDSFLSFTMQDYGNVGITSLQDRKKLFHLLQQLKKQTPPISNTSSPVINSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSGLRQPTSTSSLLSNNNLMSTQTQQSSSSSSSSSLSSKSNSNSDFMQKAQQLLKQRELERQQYAKQQQQQQSTQTKYQSSLKDFDITSSNKNNNLDDFFEDDNLYSQQQQQQQQQQQQQDFEFEEEEEEEDQQQQYDEEEEEEEEYEEDFYKEDLGEIDDGNVLDISDDEPDPNSSCIIVEGSPDEEDDDVEYIPQNESLVNGFGSMKIQQQQQQQFQPLQQQQQQQQQQQQQFYQQQIQQQQQQQQQQQQQQVQQQQQQFNNFNYSGLNEEQIKYYQQQAQYQQQVQQAQQAAIQQAQQAAALAQASQQQLQQQEQQRQQASNFFLDMNEYGQRIRVCVRKRPLNKKEIAKSEKDIIEVLPKKDLIVNEPKTKLDLSKFIEKHKFTFDGVFDESANNYQVYLHTAYPLVDSIFHKGKATCFAYGQTGSGKTHTQMGQQGDGLYALAARDIFHRLETYFKDQLQVCISFFEIYGGKLFDLLNERKKLACRENELQNVVIVGLSEKHVTSPQELMNCIIDGNKIRSTGSTGVNSDSSRSHAILQISLKNIKTNKLHGKFSFIDLAGSERGSDTYDNDKQTRKEGADINKSLLALKECIRALDQSSKHTPFRQSTLTQVLKDSFVGNSRTVMIANISPNQSSSEHTLNTLRYADRVKELGTSESNSNKKPVATYNIPAPLPPPDHLKQNFNDPILIPSTTTTTTTTATAINSQQPIIQQTSQPVSKIKQPVKQQQESQIPQTPQQQQQQQPPQQQPQQQQYNIPQTPQQTQQQFNIPQTPKQQQPIQTQPPMSPPKIDFVNYHRNHVDQFADILKKELISINQFESSKGSIPLENYINNIEQFLDSKQLLINHLRGIIQQHQQQPIQQQQQQQQPIQQQQQSTPQPSQLQTPQQRERARSQLQPPKPSIYSSRN
The following text describes a protein:
Function:
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDVDSDPAASSKPTQMDLEDQTDTKGKGKAEEGNGKGEELADSIGSLSIGPGRTNFKKKPVIIIVIGMAGTGKTTLMHRLVCDTQASNKRGYVVNLDPAVMTLPFGANIDIRDTVRYKDVMKEYSLGPNGGILTSLNLFATKFDEVVSVIERRAEQLDYVLVDTPGQIEIFTWSASGAIITEAFASTFPTVVAYVVDTPRSTNPVTFMSNMLYACSILYKTRLPLVLTFNKVDVAKHEFAIEWMQDFEAFQTAVESDKSYSATYTRSLSLVLDEFYNNLRSVGVSAISGSGVNTFFEAIEASAKEYMETYRADLDKRIAEKERLEEERRKENMEKLQKDMMKSKGQTVVLTTGLKEKNSVSDMMDGADEEEEEEALEDFGFSEDDEDEDEGEDEEVAHFGF
The following text describes a protein:
Function:
Involved in DNA recombination.
Sequence:
MHQELSKTTQDYNQLASKFDELSSIKNQFEQQTIKVQTENQGLQYRLTERDEQIHHLTQERQNLTEKLTALSQELTGLQTTLTEKEKYFSAQQQNFEQSKQQLGVEFQNLANRILDEKSRSFSQSNQTALETLLKPFREQIEGFQKRVNEIHSESVKGNAGLEAEIKKVLEIGLNMSQEASNLTSALKGEKKTLGNWGEVQLERALQLAGLEENVHYRAQAHFKDEQGGRNYPDFVLNLPDEKHLIIDSKMSLVAYESAVNSEDDFERERLLKEHISALKTHINDLHKKDYSNLIGMCSPNFVLMFIAVEPAYIEALKADPALFNYGYERNVIMVSHTTLMPILRTVANLWRIERGNAEAKEIAEKAGEIYNQICLVAERLNKLGNTLSTVSNQYNSTVTALVGQQGLVGKVERFKTLSAKANKTMPDVDLLNNQLDLARLNVLNQENLQ
The following text describes a protein:
Function:
Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries.
Subcellular Localization:
Nucleus.
Sequence:
MKRESPSLATVTYSDEKGERWKVLKWKRLRALHARTEGFVHRCSPGPEPAGGGAGGGARARLRGVSTERPARKLSFPGAATAAAAAAAAAPDHVRSRPASDPAGQLGRQGRSPEQPQKGRKASVETSTMSFVEYEELIKEGDTAIIFLGHGSMFPVQVQRGAQTQTKYGVIRHSAHLIGQPFGSRVTCSKGGWVYVLHPTPELWTLNLPHRTQILYSTDISIITMMLELKPGSIVCESGTGSGSLSHAIIRTVAPTGHLHTVEFHQQRAQKAEEEFREHRVDRWVTVRNQDVCKNGFGVSHVADAVFLDIPSPWEAIGHAKDALKVEGGRLCSFSPCIEQVQRTCHDLTEHGFIEVTTLKILLRKYNVRTSHLPMQHLVEVLDPLPVLGQAQIKIAVPLKETVGHTGYLTFASKSLF
The following text describes a protein:
Function:
Transcription factor that regulates asexual reproduction. Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity). Regulates dimorphism, virulence, and the sporulation program. Required for mating, gall induction, and sporogenesis in maize tissue. Regulates expression of the filament-down-regulated gene UM00205 and the teliospore-specific gene ssp1.
Subcellular Localization:
Nucleus. Note=Accumulates in the nucleus during teliospore germination.
Sequence:
MSTASPLHHGHGNGSYANSPAPTGVTGRDAGVAAAAVADSAVRSGSVPASASGSAPGSASGSMYGEAHTQHHTGHHHYSAHHTHSHGALTSPVNGGHSSSWSPYGYPAAPVYGGSPSPYGHNAYSQYASGYGYANGTAHHVATAPTTPSATSTAYHTGVNGMMMHHGQHAGYGYSSHHLGSHTPTHTHTHSSAYFMNGDGAHSHLNSSAHLTSPSYTTAPQYSTQLPLAGRHRVTTTLWEDEGTLCFQVDARGVCVARRHDNNMINGTKLLNVCGMSRGKRDGILKNEKERIVVKVGAMHLKGVWISFARAKQLAEQNGIADALYPLFEPNIQSFLYHPDNYPRTAAVIAAAQERQAQRQRAPGGQPSPGANGTSQAPPLMRANTTPSNGDTSTFSSGLSSLGSWTGSHDQGHASAPTTAQPSPSSMHNGATQMHMSLSNHGTASPTYAQSQQQQQQQQQQQQQQQQQQQQQQQQAYPMTAAQQLARPSVGDRRQSAPISLNNSVGHAENPYGATNLGGAANGGLVNGARKVSGLKRSWNDADDLNGSAAASPTERDMQRSGSGGSNGLKLDGDDLHSPDSSDDRLAKKTRGMPQRGGGATTAMPSMSTNMLMGVGNGSGIHHE
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MQSSTGNDGYDSYDSQPEDLTIETSEPPSHHTFPPVSFQFHTTFPDVYLPPSIPNQTTASTFVPFPFLDSHVEAEVPEVLTLGNTHTSEDLLTTQTPSASITSLKSSTVPNTGAGDGGMATFLINGVPSRMALLDTNNKTDQSVKRVQTGPSAASLTAAQLHMTAMSKTVGWEPDEEPLYVNAKQYHRIMKRREMRAKLEATGKIPKKRKKYLYESRHKHAMARTRGNGGKFSKEN
The following text describes a protein:
Function:
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
Sequence:
MALTKAELAENLFDKLGFSKRDAKETVEVFFEEIRKALESGEQVKLSGFGNFDLRDKNERPGRNPKTGEDIPITARRVVTFRPGQKLKARVENLKADQ
The following text describes a protein:
Function:
Gamma subunit of the heterotrimeric guanine nucleotide-binding protein (G protein) involved in glucose-induced cAMP signaling. The beta-gamma subunits (git5-git11) promote binding of the alpha subunit gpa2 to GPCR git3, which senses extracellular glucose, to activate cAMP-PKA signaling and repress sexual development and gluconeogenesis.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
METEALLNEKISVQQARQEFANYANNIPEPMMVSVAPPKANPSVSSKTKQQQHFKPGKATKDKATTKCCTIS
The following text describes a protein:
Function:
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MLTIKRYPGAIEFTVHTSKSYGTQMFALCFISFVIGATSLAIGRSPKIIITLVELSFLLSLFHIISGVNHESLFVIRDLGVQTNCHSIVPWKSSSKLIPLDSIRDIFINEGFRKFDVCYYMGIAIESETEIHVVFPTLLPRHDVLQKVYKETVILLANNS
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as non-selective cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRMISRRSNGAVVPVLVVLSSWLLYVLLYVMSHESKLGEAQSSGTPSRAVQVGALLDLGTAGGKATMATISLALEDFYASQPGSTTTVALHVADCEDDEITATSAAKHSKYFVRTALDDSSQVPAIASLVQLFNWHQVVPIYEDSDFGRGIIPHLVDALQDIDAHIPYRSVIPSVPTEDQIKAELNKLKTMQTRVFVVHMSSDIAARLFVLAHDAEMLTDGYAWIVTDSVGNMFSSFDQRTINSMQGVLGVRPYVPPSDKLINFPPWFVARYRQQNPGAPDPANPNVFHLWAYDTAWAIATALRKVGPLTLGFQMPSPQNSNSSNDLSMLGVSQDGPGLINAIRATRFQGISGDFVLADGQLQASVFEIFNVIGNSYQNAGFWTPKFGLSKNLIVSSGPSRTVGLNMVLWPGGSVQPPRGWEWPVAGKKLQIAVPVKPSVNPFVNVKKNVATGKFDVTGYCIDIFEAVMREMPYAVPYEYVPVVDPNIATNITLSYSEICYQVSLKKYNAMVGDTTIIINRSKLWLDKLVVYIFADPKLKKWLSKFALINFLLLVWLLEKLYSASLTSMMTVRQLQPTVADLNQLISNGEYIGYQSGSFVKDLLKSLNVDERKIRSYRTDQYAEALMKGSWNGGVAAVVDEIPYLKLFMSKHCRNHSIIGRVYKTGGFGFVFPKGSPLVADVSRAILKVTEGDEIVGIERKWLGLDKVTCNSMTNALEMGSVVTWSSLKGVFFITFGLWGIAGIIYIVIKFWPWRQTESTVQEAIAELVLEHSNGDEQDDTIWPIERNSHLVFHLRGHPPQAQVAGPQGDPAEPPPAQC
The following text describes a protein:
Function:
Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
Subcellular Localization:
Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MDVKSKFFQNGNTMNGLVKFITELRTCRARDLEEKRINKELANIRLKFKDSSLSGYQKKKYVCKLLYMYILGWEIDFGHVEAVNLLGSTKYSEKQIGYLAATLMLNETHELTRLVVNSIRRDLESHNEVFNCMALHAIANIGGREMSESLINDIFKLYTVSSRSPFVKKKSGLTLLRLYRKFPDLVPGAEWADIILPIMSSESLSVALSATNLVVALAQQYPDAYSGCVTRVVSILYKIIVRGDYPSEYAYYKIPAPWLLVKFLRLLQYYPVPQSQTVLDELLTILSKILSNPERPKNPQQLNAQNAVLFEAVNLAIHLESRHSLISQAVVILGEFIVSKETNLRYLALETMSHIAALGDPLSSLRNHRITVIDSLKDKDISVRRRALDLLFSMCDVDSARDIVTDLLTYLNSADYEIREEMVLKIAILAEKFATEYTWYIDVIMSLMTTSGDHIGDAIWHRVVHITTNNEDLREYATYTTLQALKQPNCHDKMIKLGGYLLGEFGHVIVESPGCSPLDQFLALHNNFSMCSPACRSLLMSSYLKFANLFPEIKPQIIQVFTNLSHVLDVELQQRACEYLAIVTLPEDKILQAVCDEMPRFPDRESSLLCQLHRKLHDTEDVRIWTIGGKDAQADLQTHRDNAKLNKPSEAQTLEKSTPQAKIIDPIAALAKIPSNTDVHDLIGVDEPTISAPELADSNDITEKFNALLLTQSGVLYEDTVIQVGIKAEYEGNIGRIAIFFGNKSSVLPLTNFQTVLSSTDQIKMDLIQPISSSIPSATQLHQMYNAECIDIPVVQLMLTITFNIGGHSVSRNLKMPVVLTKFISPIVLDGDDFFLRWRQIGGAPREAQKVFSANGVIDIRASKAALVGFQFASLENVDPNPNNCVLAGVFSSTHLGKVGVLVRVEPSLQHQMFRLTVRATNETVSQKVCDALSEALLRQ
The following text describes a protein:
Function:
Probable E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled (By similarity). Acts on both canonical and non-canonical Wnt signaling pathway (By similarity). Plays a role in the migration and axon guidance of different neuronal cell types including CAN, HSN, AVK and AVG. Promotes the differentiation and regulates the anteroposterior polarity of AVG unpaired interneurons by sequestering the Wnt signaling proteins cfz-2, mig-1 and mom-5 to endosomes which thereby reduces their cell surface expression and negatively regulates Wnt signaling. May also regulate AVG polarity and axon guidance through Wnt-independent mechanisms involving unc-53/Nav2, unc-73/Trio and cytosolic protein vab-8.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Early endosome. Late endosome. Perikaryon. Cell projection, axon.
Domain:
The RING finger region is required to block Wnt signaling and is also required for endosomal localization.
Sequence:
MRLLLFILLNTTLLSTNYVHARPSVSHTTLASQFKFAEKADIFVTHTNINEDRTQDEKTIKLSGTFSPVGSNYETGGDIVQVSSFRACDARRKGLDNTVFEHVPVVFYDDVEKFLTGCVALDNQARFAEKSGAMALIVGPASRVERTTRPMMIGGSKIPVIVLDDEQTERLRSELRSASERGAVTKLRISFIDEKPTKVLKLQVFRPTVLNITLLGLLIILIVFVSLLVVVKIRCQPTMHRELWLRALARTALTKMEIRSFQKEKNVEAGQKKKTSSTFARLKQHRSSSSRHSSYLAVFGSLTSVAQSSSHSAQERCVICLEEYEEGTELRVLFCGHEFHPKCVDPWLLSKRRCPLCQFDVVYKHYPKVDSPEKLSGRSDDTTSLLPRTSPSEDLPSAPSSRSTRLTRPYRTTHHLIPSSTRPSSHQRPSLQPTAPRTRSCPRRRQLRSRNQIDFSIRIGGYSSDVSSSHAEQSRSFEIEPRTSQQL
The following text describes a protein:
Function:
Recognizes and binds polyubiquitin chains. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Aspartic protease. Appears to act as negative regulator of constitutive exocytosis. May act at the level of secretory vesicle docking and fusion as a competitive inhibitor of SNARE assembly. Required for S-phase checkpoint control (By similarity).
Subcellular Localization:
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Domain:
The UBA domain specifically recognizes Lys-48-linked diubiquitin units (Ub2), which is mediated by the two binding sites within a single UBA domain.
Sequence:
MNNLTPENIRQTILATPFLLNRIRTEFPQLAAVLNDPNAFATTWQSINASQLLQIPSSTYSMGMPSFSEDDLFDVEVQRRIEEQIRQNAVTENMQSAIENHPEVFGQVYMLFVNVEINGHKVKAFVDSGAQATILSADCAEKCGLTRLLDTRFQGVAKGVGMAKILGCVHSAPLKIGDLYLPCRFTVIEGRDVDMLLGLDMLRRYQACIDLENNVLRIHGKEIPFLGESEIPKLLANVEPSANAHGLGIEPASKASASSPNPQSGTRLGTKESVAPNNEGSSNPPSLVNPPTDPGLNSKIAQLVSMGFDPLEAAQALDAANGDLDVAASFLL
The following text describes a protein:
Function:
Insulin-like peptide which plays a role in ageing as a consequence of daf-16 activity.
Subcellular Localization:
Secreted.
Sequence:
MPPIILVFFLVLIPASQQYPFSLESLNDQIINEEVIEYMLENSIRSSRTRRVPDEKKIYRCGRRIHSYVFAVCGKACESNTEVNIASKCCREECTDDFIRKQCCP
The following text describes a protein:
Function:
Involved in the import of sulfate.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MELAAILFSLFFAMNIGASGAAASMGVAYGSGAIKKKTYALILCAVGVFAGAVIGGGEVVKTISSGIIPEQTITLTIVCIIIGAAALSLFTANLLGIPLSTSEVTVGAVVGVGVAYKVLFVNNLLIIVSFWVFVPLFAFGFTYFVSKLFRYFKIEVKSSKKQKILGIVLLVAGFFEAFSAGMNNVANAVGPLVAAGVLDVGKGTLYGGAFVALGALLLGRRVLETNGKKITRFSKGEGILLSGTGAGLVIISSVFGMPVPLAQVTSSSIIGIGMAKNGPNVFHKQVVQTMLKVWIVSPFLSLSISYLLVSLFLKADYYSIFIMVSVLLAAGGAISLTKAIRKERRSVHEQGGGI
The following text describes a protein:
Function:
Involved in regulation of pyruvate dehydrogenase activity.
Subcellular Localization:
Mitochondrion.
Sequence:
MNFFTSAVGSKVFKRNNFKYVAIAASSIGLAAYHIRKDAIALDIPNSTYQHVSKNRVPPTDGDGITKRLKEFERTVTVNKDGIFRYDFNQVASNDPCEDDHVEVIDRNIDEGNWYFWGIFDGHSGWNTSLFLRQHLVPAVVRELQKCTASYYHQNACPSSLALDKSISEAFAKVDHQIVHEHVSHVFNNPESLQVAASLLLPALSGSCALLTSYSAKSKSLQVACTGDSRAVLGECTPDGSWEAIPLSRDQTGMNPDEASRLEVEHPGEEVLRNNRILGRLMPSRAFGDARYKWSQEISERLHREYFSASPIPVKTPPYVTAVPEIESITVNPKKHRFLIMASDGLWDTMSSEQAVQLVGEWADTVLGKTTNEKNTTQDDKQSWSLFKKTSKVIDDNAATHLIRHSLGGSDQRISALLTLTYPISRRYRDDITVTVIFFDEKTL
The following text describes a protein:
Function:
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Sequence:
MLAGNFTVSSTAFSQMARCQVTTVGGGDDAFNTFSETGAGEHVPRAVFVDLESTVIDEMRTGTYRQLFHPEQLISGKEDAANNFAHGHCTIGKEIVDLFLDRIHKLADDCTGFQFCWWWYWFSVLSTHSLLEQTDVSILLDNEAIYDICRRSLDIERPTYTNLNRLISQVISSLTASLRFDGALNVDVNEFQTNLVSYPRIHFMLSSYARHFF