lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable transporter of a GTP-driven Fe(2+) uptake system.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKALTIGLIGNPNAGKTTLFNQLTGARQRVGNWAGVTVERKEGHFNTAQHQVTLVDLPGTYSLTTISEQTSLDEQIACHYILSGEADLLINVIDAVNLERNLYLTLQLLELGIPCIVALNMLDIAESQHIEIDINTLSKKLGCPVIPLVSTRGRGIDELKNSIDQFQPATCRTLVSYPPILLSEVDKLVAAMSDALPMQQRRWLALQILEGDIYSLNRAGVAPSMVEQARQQLREQQHEDPALIIADARYQSIAHLCEAVGNSQQAEPNRLTQALDSVILNRWLGVPIFLFVMYLMFVLAINIGGALQPIFDIGSAAIFIQGLQWVGHTLHFPPWLTIFLAQGVGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVGFGCNVPSIMGARTLDAQRERLITIMMAPFMSCGARLAIFAVFAAAFFGQDGASIVFSLYLLGIAVAILTGLVLKYTIMRGEASPFVMELPVYHVPHLKSLLLQTWQRLKGFVLRAGKVIVIASIFIGGLNSFSFNGKPVDSINDSALASVSKVLTPLLMPMGIHADNWQATVGLVTGAMAKEVVVGTLNTLYTAEQINNDPFDAENFNLLDELAGAVDETWQGLKDTFSLSVLANPIEASKGDGEMTTGSMGMMSSKFGSSISAYSYLIFVLLYVPCVSVMGAIARETSRGWMTFSILWGLNVAYSLATLFYQAATFRDHPQESLSIIVLVIVVNALILFGLRRARSRVTVRLQNSEPANCCRSSGSNCH
The following text describes a protein:
Function:
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).
Sequence:
MSKAKNSKYPPPGIWYWVWAVWGFFKTIYICIYWHAFYPKVAAINRVKLLEKYKQETKLVNTTTWDFIKFLFFDIDNLVGTSFEPFNPGRIKVGQVAPAAKKYGDRANFLTVYIAEAHPSDGWALDLSNDSIGVCYRAPRKVEDRIYIAKEFIKNYNYPVPLYVDSITDDTLKTYSSMPERLYIIKDGKVAYKGGPGPYCYSLEEMEEHLLKLF
The following text describes a protein:
Function:
Involved in vesicular protein trafficking.
Miscellaneous:
MISCELLANEOUS: Present with 3190 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MSNLCVLFFQFFFLAQFFAEASPLTFELNKGRKECLYTLTPEIDCTISYYFAVQQGESNDFDVNYEIFAPDDKNKPIIERSGERQGEWSFIGQHKGEYAICFYGGKAHDKIVDLDFKYNCERQDDIRNERRKARKAQRNLRDSKTDPLQDSVENSIDTIERQLHVLERNIQYYKSRNTRNHHTVCSTEHRIVMFSIYGILLIIGMSCAQIAILEFIFRESRKHNV
The following text describes a protein:
Function:
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
Subcellular Localization:
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Sequence:
MSAVDSSTSSGHPEREAQHETGLPPLETLISHLVAAKRSLSAINHVWRANEIVTSARSALEESVVVSARTGFLRSGLNNQLRLLYNVRAEVEEISLRGRSEFANALKSLDAADARLKKTLGLLRETIVHASFRPEGEEPKSLHDFVDERGVEELHSTLKSSIDRTNAAQADLDASNNAFDVELQSIKQALSTYRATTKLASSRGSVSSSGSQSGSSSSLPSISSMPSMVHSLEMHAQEMANLLESLVRHFDLCVTAVKHTEGGGAAAQSITGDMPAGVMGSHPGPGHGAGTGPTIEGDFNANPNAPLDPLSASEYREMVSVIVNDAAEAEDVVMEIQDRIGEMESVLETLTAQRDSFAAIYNATKEVFSYLSSLASTRLPGYIAQAHAFTAVWNDEHDRIKGGLADLSDLNALYDGFLDAYDGLIIEVARRRHVRHRVEKILRDARNKLDALYEEDVNARETFRVEQGDYLPSDIWPGLSREPMRVEFHRISGGPLKGVLQSPDQAQSPQPNEGEQLGHQDPQNPGDADSRFGEVIPDLPQELVEQALARLKSKRQR
The following text describes a protein:
Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Subcellular Localization:
Late endosome membrane; Peripheral membrane protein.
Sequence:
MESFRDKTVDELKDLQENSEEIERLALESNEVQDLQLEREMALATNRSLAEQNLTFQEPLETGRANLSDKYRELQKLVEQCQEQKAKLEKYSKAIQPGTLLSLLQVEGQKIEEESEAMAEKFLEGEVPLETFLEQFSSMRKLSHLRRVKVEKLQEILRKPQSSQEPPNSTAFNHQHPSGIPAGPVIQQPQTSVAGGPPFPLPYSLSPGMPIGPSAHGALQPAPFAGTSAIEGYAASQSYPQPPFPYKHLSGPGYPPLPAGGSGPQSQASDPSSSSPGYSWSPSRTPPTRPGYPQPPLASSTRPGFPQPQYFPSSGKPLCPYPTQPTVPNFPVPSQSQYPTGPSQSFGYPPLPPRGPNWSGY
The following text describes a protein:
Function:
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
Sequence:
MASYWAVCVVLVAGSHLVAGTAEVMSHVTAHFGKALEQCREESGLSTAVLEEFQHFWRDDFEVVHRELGCAILCMSNKFSLMQDDARMHHENMHDYVKSFPQGEVLSAKMVELIHNCEKPYDDIKDDCERVVKVAACFKVDAKKAGIAPEVAMIEAVMEKY
The following text describes a protein:
Function:
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular Localization:
Cytoplasm, cytosol. Rough endoplasmic reticulum.
Sequence:
MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMRRQCFRQYAKDVGFIKLD
The following text describes a protein:
Function:
Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
Subcellular Localization:
Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein.
Sequence:
MDILLNQTNRLIHEIQSYLQQIAYQDDEQAKVSENGITCRLQQLSTNCEKLQIQVSKLPAAQRQNVKYRIDQVVYDYKHLQSGYNQYLQAKETKQREAREREELLSQDYKTNQETAIDMDNSLLHNRSLTNANRQMDDLLTSGANIMSDINNQKSILKNTHKRLLDIGNTLGLSTTVMRMINKRAAQDYRIFIAGVIVCCLFMYVIIKYLT
The following text describes a protein:
Function:
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of the antibiotic 2,4- dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde (DHMBA) and its derivatives. Is probably involved in the transport of the metabolites to the environment (Probable).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTEQPPQNHSVDLNQNEDNNENDYRSSSATDAERPCEPKIEESTAKPPTGPPAPPPPPNGGLVAWLHVIGGFMLFFNTWGIMNAFGVFQTYYESGALFERSSSDISWIGSIQATMLLLVGFFTGSIYDRGYLRALLVVGSFCIVFGHMMLSLCKTYGQVLLAQGFCVGIGAGCLFVPCVSVLPTYFSSRLGTALGLAVSGSSMGGVIYPIVLNELIGPLGFGWSVRVIGFIALGTLLVPIAVMKQRVKPPRARALIDWSAFSDIPYMAFTLASLLAFMGLFALLFYISYFGAAKPITDTRMAFYIVPILNAASCFGRTIPNAMADKIGPFNLIAPCCLAVGVLILCLLAVTTEAGLIVIALLSGFFGGALIGLPPLCFVALTKDKTKIGTRIGMGFGMVGLGVLAGGPAGGAILSHSHHSNWTGLWVYGGVTSLVAGFIICIAV
The following text describes a protein:
Function:
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
Sequence:
SNPVLTCLYNNLVYEYTDGSAGESRKKVTITALRKLYNTKTPITVMTAHDYPTGLLVERAGFDICLVGDSLAMVGLGYESTNKITFEDMIHHTRAVARSSKCAFLVGDMPFGTYEVSPEVALKNAIRYIHEGNVEAVKLEGGIELKDTIKRLTDVGIPVMGHIGLTPQRQTSLGGFKVQGKTLDKAQKMLQDALALQDAGCFSIVLEAIPYPVAKFITDQLSIPTIGIGAGPDVSGQVLVMMDILGIYDKLSPKFSKVYANIGEQAVTGLSTFIDDVRGSKFPVIGLHTYKMAASEEERFKEWVAIYESSKITTL
The following text describes a protein:
Function:
Component of the A-type ATP synthase that produces ATP from ADP in the presence of a proton gradient across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFRPEEMVKLEVITLNRYKDTLLTYLHEAGAVEVREVKVELAQKDTPNEYHRKAASYSISMSRLVEFLGTYRKAAGGGIKEFFFPKEKPKRTYRYERLEKLIKDVEEFLGKVEPEIKAIEGRMNSLSTEIERIKEQIGILDILTPLNIDVSYLRHCGVVEVTVGLVDRTRVKELADALKKETENHVAIITKEASDKALVVIVNLARDHDKVNTLLAKFSVEKLEIPEGEGTPKELMKEYSKKLAEKEKELEEAKKEASKLAEKYYDDVLFYKELVDNERDKSTVLPMLARTNMTFALTGWVPRPDVQKILEGIKRITEGKAYINVREPRKEELEEMPVKLKNPGWARPFEMLTEMYGVPRHDEIDPTPIIAFTYSFFFGFMLTDFLYGLIVGIVAALLVKGHKKFNDGTYKFAYILLWSAFFTMLLGALFGSYFGNAADIMLQYITGDQNAHAWRLLDPLREPMPMLLAALAIGLAHLFLGYTLGFVIKWKNGDRKGAVFEQLPWMIIIIGVALLASQREGLDAAAKAILGTGIALFAVGELVINGGLAALMIISDFFGFVGNWLSYARLMALALATGGIAMVINVLVGMVWAIKFLYIGPIIGLIIFFGGQLFSTAINALGAFVHALRLHYVEFFGTFYSGEGKRFEPFKSKREVSKLELEV
The following text describes a protein:
Function:
Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA.
Subcellular Localization:
Cytoplasm.
Sequence:
MWWSTLMSILRASSFWRWISAQTERIIRALRAHFDRIMDEPSPLARLALELNQHSRFIIGSVSEDNSEDEISSLVKLDLLEEKEGSLSPASVGSDALSDLGISSLQDGLALHMRSSMSGLHIVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFTKRILNVPQELYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGLSPWGDAPIDFENSAHVPCARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVVMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIHSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHTSLYDEDKVPRNEPIHILNVAIKTDGDIEDDRLAAMFREFTQQKKSTLVEHGIRRLTFLVAQKVLDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTHAFLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGVENLRSSGMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAAALNKVLGREVYTSNNQLGGIQIMHNNGVTHSKVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSILEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSAAERKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGIINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVVRILSTMDSPST
The following text describes a protein:
Function:
Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
Sequence:
MSTASSSSSLPRNPVGGHVPVAGGLHSVGLSYARELKAEAVQVFVANPRGWATPAGNPKQDEAFREACAAGSVPAYVHAPYLINFGSHTGATVERSVESLRHSLRRGRAIGALGVVVHTGSATGGRERPVALKQVREHMLPLLDELTHDDDPYLLLESTAGQGASLCSRTWDFGPYFEALDAHPKLGVCLDTCHIFAAGHDLTGPSGMHQTLDLLVDTVGEGRLRLIHANDSKDVAGAHKDRHENIGAGHIGEDPFRALMTHPATDGVPLVIETPGGKEGHAADVARLKKLRDG
The following text describes a protein:
Function:
Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MEKLKEFLKGVRDELKRVVWPSRELVVKATISVIIFSLAIGVYLWILDLTFTKIISFILSLRGSL
The following text describes a protein:
Function:
May function as a transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MAELLMECEEEDLEPWQRRIKEVEDDEDDDDDELIFVREISGAKQPPANNAQVTQPNPFPCAENGTPIRGNTASFCPSNNHYKTASTGNTIAQPANTMYQPVTRPATSSAIVQPLPRPVGSPEPLKRPLTGCFPSHQPPRPSPTILQPVCRPATAPSNAQPACRNNAFPTAAQPAVRPVATITAQPVILNQGYIVNSPQVSSSNPPNVMYTLRPSTTLTQYQGVHPLSVTVNATPLVRPVQPLSQSLPVSVPTRTVPAAVHRPFPQMATVAKNLNLVTEPQQCLILNSQKTHQGISTQSSGASIGWNDNTVSEKRPAPIEISDDSPKKTKNAENECDNRLTDLSTSVKPPTLSQSSPTKVNAGTSSGTTPKHGPPFPRACPKCNIHFNLLEPMRKHMKFCCPDKVDHFFSGLANIEAMNAPGMIEDAEKGKLIMLVSDFYYGRYGGDLDLTQQEQKTHTFKCYSCHKVLKNNIRFMNHMKHHLELEKQSSESWENHTTCHHCYRQFPTPFQLQCHIESSHTLYESSTICKICELSFESEQILLQHMKDNHKPGEMPYVCQVCNYRSSAFAEVDSHFRCAHENTKSLLCPFCLKVIKSGTPYMQHYMKHQNKGVYRCAKCRLQFLTCKEKINHKTQHHRTFRKPRQLEGLPPGTKVTIRASVGSIMNSVPSPTNTVCTSPPSTAFQASPKVTDAKITQDLLVKSNEQNTKTKVSSPTPKKKPVSTTTTKRIKMINTALQNLRSVAGYYKCIECQLEVKDFEGHFHTYVHCSKCKFSTSCNKAYMNHMLSFHGRGSSKRAKASKKPLKDKRRITLVCLNCDFLTDVSGLDDMAKHLSESHNHSCQVVLENVSIFSSTLEGDMAKSRNESSVGERLKYCKIMLYDTKKIQSKGENNTVKTMEESGTSESSKISDVHRDFSSHDKHVTPVEPVKDSDQTTQDACNTNPIIGIAGTNSDHKDLMSTVEGEISNRDLTSETDQNIDSTYISDTLDESKASLEDVTLNIESQKPSFAGEENSFVQFLRGREEPESICSDVSEQSSVHLEPLTPSEILEHEATEILSSN
The following text describes a protein:
Function:
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
Sequence:
MSIDFTPDPQLYPFESRWFDSSRGRIHYVDEGTGPPILLCHGNPTWSFLYRDIIVALRDRFRCVAPDYLGFGLSERPSGFGYQIDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAVERADRVRGVVLGNTWFWPADTLAMKAFSRVMSSPPVQYAILRRNFFVERLIPAGTEHRPSSAVMAHYRAVQPNAAARRGVAEMPKQILAARPLLARLAREVPATLGTKPTLLIWGMKDVAFRPKTIIPRLSATFPDHVLVELPNAKHFIQEDAPDRIAAAIIERFG
The following text describes a protein:
Function:
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
Sequence:
MIISLIAALAADRVIGMENAMPWHLPADLAWFKRNTLNKPVIMGRKTFESIGRPLPGRLNIVISSQPGTDERVTWAASIEEALAFAGNAEEVMVMGGGRVYKQFLDRANRMYLTHIDAEVGGDTHFPDYEPDEWESVFSEFHDADEANSHSYCFEILERR
The following text describes a protein:
Function:
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of fumonisins B1 (FB1), B2 (FB2), B3 (FB3), and B4 (FB4), which are carcinogenic mycotoxins.
Subcellular Localization:
Nucleus.
Sequence:
MAGSIVFVTDNQISANSRHKPRFRRRRGACESCKRRKVRCNGTNPCNQCQKSSIECLYSSSSWKANDGDTERGPSGSPVQHTRGSLTPPQTSPYGGMACNGSAEESSRFDGSDAHSLLMSLSNTDCTTNTEATEMSQWQNWFVSDLPLGSDVQLTGTSDESLTDWLDPQLVNPADTAAIMQTLSGEDLFKSSGPSYGMSEPPSRDSDPGFNTARNEQIAGFIQKLRSQRPFVLRDENPEAPPGNIRGFYDAKFISQCFDACDADPEGVRVLLERKSMDLIADEITKYALAVDTETSVLFHSLMAIGCHSLNLDQGHRAIGKGKYPASKFFKEALNARQHLRDSPSLGGLQAILTMAYFSARVGDDSTSSFLADAAFCVQTLQLHNAGAIEQKYNSFLEQQVAKRALWFLYSLEKPRCLAQGLLPLIHDDFVDYDPPPSANYSTSEVDWFAINARFARICSSIIKERLGCKLGRTPSRRGKDRASEYSASSVIKRLESLLEEWRDDLPFAGDFDATRSDEFAASTCAERRHRIKCLNKYWSAIIATHSGQARGVAEDGGAGVRLSRARCIDAAQAILQNSHYVTSTDILSDISLYYYITVATRVIMTVVIRDRFASDITGDPVQKNTATRKRETTHGRSIMSYVGIAIGLFSRLSLDIDVPVDEVTELGKLGR
The following text describes a protein:
Function:
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Sequence:
MKDLLRTNTSLHESVEKLLNLQSKIESDASTKYLAMAAWLDRNGFENTAGYMYKQSEEEREHFLKVFKYITEMGGIAVTPSVSEVQQEFASFREVFEIALQNEIAVTHAVNKVIAKCRQENDYATEEFMMWYVKEQREEERNARRALELFDLIDEDSATGKFQLDKEIAKIGAAE
The following text describes a protein:
Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAGLSAGYDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKMIKKNSYNRIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISLYIHAYTLYWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYKDINVRDAIEDIYKFILTSDDHMNKNNLQNLVNFSWICKESSYEFQNIHEEILTPALNKAVEYIEKLN
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MQDIPLKTNSCAESTIDISSNSDLIPESTVDNNSSLIEAQYNSGLAYLENKKKVKGQQNQNRDNAPTMDSTESTVDVSSNPGLIEACDNSPLMRSGNKKNRKRRRRKRKSSAPKTDNTDADLQEVTSKTMTAPFGMALVDMITKAVSETDPLEVEASGDTSLKPVLAAAPKETNGSVDTSVKLDFPKNLSRSKRKRLRRKLHKESLHVLERDAKDCALAGDKSLKNNMLQEKHSSLQPSVDICSQNELVVKQSNGDVCLFNGHNAFENNGVIDLHMANGKQLEKKEAKCAPKVTELDLTTMRKDFPISEKQSSSSNSANRSLMENDDVHPESHPVSSETRTIIAYKRKKRVKTYIWTKKKKCSNLLVNGVDCIKEDGDSLMKNVSLLTEGHIEQKLSDKLDKIQITVHDASHGNDVSDEIPSHPKEYNISGHDRSCKLPKKQHVEVETKTTEGFPPSHLGVVESGTGLHDSSEEENHSQTLQYPPGNVCIGHSKKKLLVLDLNGLLVDIVASPYHRYRPDKMVSNKAVFKRPCCDEFLSFCFERFNVGVWSRGSRKIWTM
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
Subcellular Localization:
Nucleus.
Sequence:
MTVSQNHSIKSPLFHNIIAVPPQFCSTLTLSPPIMDSMDSSRTIPSHQSQSPCKNHISIPLETENFHEDSEKRGKKLTKRGNNDNTGRRYLGVRQRPSGRWVAEIKDSSQKLRLWLGTFDRAEEAALAYDSAARLLRGRNAKTNFQYHGVMNTYEENCNLLGKNPRLYQLLQLTITKNHARSTFLKSIGTVPWQNQNIGNKVDPVDFDTLVEETIFCSPTSDQDEGCNNNLSQLSLGSSKVYSSVVVAPSFCASLDQGGGEGKSCQDA
The following text describes a protein:
Function:
Involved in DNA replication and cell separation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MVNPPQPRQMPKSPRLSTSTSSGPSAVPNLLGSPRPSPPQLQHQPSSASTSSTTSTATTGGSISATAPGSTQHYLHHHPSRKTSIVEILSSPPPLPTDPNDPIHQLSLSRHASTSSNKSSSQSIAPGSTAITNHAFSLVDWSEIPLTELTESNKLISIHSSHSVQSAFETLLKNNLTSVPVSISKSDPHDLTNCLTFDYSDLNTYLLLIMNKINYSELNVDDIGDPNISPQERHEFVTQTISKAKRGEEVPVEFIIKLHPKNPFIKFNETDTLFSVMETLGNGVHRIAITNEEGNKITGILSQRRLIKYMWENARRFPSLDFYLTSTLQDLKIGSSNPITIYEDQMLIEALHKMFNERVSSLAVIDRSRTLIGNISIVDVKNVTSSKNSHLLFKSVLNFISYNLSQKGIEEGQDQFPIFHVNNQTSLGRVIAKLVATQSHRLWIVDSSRQASSMSSASASAPNSGMNNGVTVGYPAPADSSITDKAEEVEASSMSSPQLNAAAAAAAAVATGAPTTATSAQPDFSYTSGTGKLVGVVTLTDILGLFATSKGRRTDPQAARNQRRRSSTSTTRSSIDSALSAEGILPSGSAIIGSSNAANTGRRGSVEVSSDVFRKSYTKAQENAFSKE
The following text describes a protein:
Function:
This is a Na(+)/H(+) antiporter. Can also transport lithium.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MELMMAIGYLGLALVLGSLVAKIAEKLKIPDIPLLLLLGLIIGPFLQIIPSDSAMEIFEYAGPIGLIFILLGGAFTMRISLLKRVIKTVVRLDTITFLITLLISGFIFNMVLNLPYTSPVGYLFGAITAATDPATLIPVFSRVRTNPEVAITLEAESIFNDPLGIVSTSVILGLFGLFSSSNPLIDLITLAGGAIVVGLLLAKIYEKIIIHCDFHEYVAPLVLGGAMLLLYVGDDLLPSICGYGFSGYMAVAIMGLYLGDALFRADDIDYKYIVSFCDDLSLLARVFIFVFLGACIKLSMLENYFIPGLLVALGSIFLARPLGVFLGLIGSKHSFKEKLYFALEGPRGVVPAALAVTVGIEILKNADKIPASITKYITPTDIAGTIIIGTFMTILLSVILEASWAGMLALKLLGEYKPKYKEESHH
The following text describes a protein:
Function:
Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation. In the 4EHP-GYF2 complex, promotes translational repression and decay of mRNA targets by recruiting and bridging the association of the 4EHP complex with decapping effector proteins, such as me31B and Patr-1, and the deadenylation CCR4-NOT complex. Involved in regulating starvation-induced, developmental and physiological autophagy, which is critical for eliminating ubiquitinated proteins and dysfunctional organelles in order to maintain tissue homeostasis.
Sequence:
MTDSMKFGPEWLRNMSAEPSGSPSTYNVGNAAQNNSIGGHNLGNNTAASASRNLFPEYRYGREEMLSLFDRNCLLPQILPSFKKLFVEKVQCPLALTPSSEEDINQNSLGNNSRPAWLQRSPSGFGSASRGSGRGGTVDRGRMRGKSAYHPIYQRPSGLYDESLSVISKAERTWSDRNGTGDSAATTTSTSGSGALDWNGTPSSSPRKDYSNNHRNLENWRRTRNEDGSGDGPSSSGSMSGPDIAGWRSGVVGGSTNAGFGTNSHRWGRSTSWRDEDPSVDNAASLQRSISTVATLSTDRTGNNKGSGIGAAEGVGSISHPRLSSSKISQLWTVNNAAGVDADENLPEWAIENPSKLGGSFDASGAFHGDTDLKPIKSSHNTLKTKSLDSYDDVKRPKSKDLSDPDSGNDITPETSLTKDTNTTAVQEEVESSLSPISSTTTKEVIHGDISDRIKEVADEVEKLIMDDDHKISSNQSQHQNHDGFTAALPRMADIEINVKPSVTAVHRQAPSTMPIQITPTITDVAPPSHAVVSFSDHETMQHHNMHHLPQFPMIPTPHIITPNLNELWFYRDPQANVQGPFSAVEMTEWYRAGYFNENLFVRRYSDNRFRPLGELIKFCHGNMPFTHSHLLPSPIELENIPVGQIPAPLTASLSITPHKPSPIPIALSVVEQQLQQQRDEQLKANVTATAEALRAAIKGSFGGNSIGNTSHLLTMRFQMLQDQYIQHQEYQILAELSKNECFQRLSAVEQETVVRRKVQLLGLPEYLISLNGLSNSLSVLNPVAGRQLYRAVVEHAKKDQQHIFANTEQQRSVGNLLDANNFILNAQIMIQQSQQEVGPLVSSVDCIMQGGTAADLNKPNEIPRNELDLINEYNLRMLLRGQPTSTQQQPPALTNSATENLPGVDFLTETQLLERQNLMIPIWLPPNNNKQQETDQQWAEMSNADASLWETANLNEERNEDQQLLIQKSSEACFADTEKDVKIAQLFQVQSGNVVNHTALEELDQSPQNLKGSHNQKIVKSLVSDIQQNHNEELNSHQHQVKQANKQNLNTKQNAAQSALKPINNENDRKREQTEEKKRQREERKRQQLEDDKRRALNESEEQTRQIQEEKERQQQIQAQRRKALLGNVHSLSVQNGMSGTLASAQSKKNDDAKTAEPQVSSRLPSTSVAPWSFQLQNSMRSAPGLAEIQKAERRERRADQQRHQELLDKQLRANAAAAAEANDALLKWQSTPASAPVMSLAEIQAEEARRLANDLVDRQRRRELEHHQQAPLSSAVLVTSATSNIWGNANKAWSSSAAQSLSLKTSSGTGLWDEPNPLGSNGSGTSGTSSVTAAAVLAGGLNSANKSTLQAQNKSSALFASPRNLRKSQTLPALSNPEKSNKNGPGQRPEKQKLAQTRSKGAAVSIEEKDRERKLNAKSQQSSTDQAISKVNEYENEFTSWCIKSLDNMSAKVDVPTFVAFLQDLEAPYEVKDYVRIYLGDGKDSLDFAKQFLERRSKYKSLQRAQKAHNDDMCKPAPAITPSANDYADSKNKQKKIKKNKMTKMDARILGFSVTAAEGRINVGIRDYVEGP
The following text describes a protein:
Function:
Plays a role in vesicular protein sorting.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MSYAESVEQATGVIKQQTVLIQRHLAQRKLLDALKHISIMLTELRNPSLTPKQYYELYILVYDALSVLSQYLVENHPKRHHLADLYELVQYAGNILPRLYLMITVGTAFLQIKDSPREEILKDMIEMCKGVQNPVRGLFLRYYLSQRTKEWLLPQNGPAGNASEGRSQENVENNVKKFNVEFIINNFIEMNKLWVRLQHYGPLRERELRTKERRELQILIGSNLVRLSQIVEDDSKLYAEVILPQLLDQIVQCRDVVSQEYLLDVICQVFPDEFHLATLPTLLETTLKFNPDVSINKVVSNLVERFNGYVERQSGDIDSVQNTFRKLCIQGQPTSASGDTISSSGGLFFVFWRYLEKLSEQRPDLPLNDLFPLVQGILKLSLTWYPDVLSNVDCLFKFTVRKCQENGGPDANPDYEYLFQDLLLSMTSSSMFYRVLTECESYQKLLSMQPVGLQKLVVNCILDTIFKAGITITNRIHLEKILLLCESLIKVNNPKIHNSGEDAEQHSAQDDDPTSCLLNIEQEKLAQVVHICRSQSIEKQVELLLTCKSWFYKGGIQMRYTYPAVVTAFWKLIRKTDIKKSKYPSREKKYRQLIKQLFKYVSRCLSELGNTVGAPCADLVFKMNLQSAAIADHLGLSEISYDFFTQVFTIFEESLSDSRSQFQAIITMAQTLQKTRSLYVENYYDSLITRCTLYGSRLLKKQDQCRAVYLCSHLWWATEIPLIGEEEGITDTFYREGKRVLECLQRSLRVADSIMDNVQSCQLMVEILNRCCYYFVHGDESATHVGPKYINGLIELIETNLKSLKIEESVEFAESKLPKPSYANFVVGVDGSYIQVPTSPTATVAAVMSKPPNITISSLVPIVTGYLQRTLNYIEDQKVVDDRFRAIIV
The following text describes a protein:
Function:
May operate as a cation/H(+) antiporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MNQNSTTELVCEAFEAHKMIRFKHDDENYFSFSPVLVQIGLVTLLKTFFQFLLMPFGQQRFVPEILGGIAISPSFLGHMERINKYLFAPRSVMILDTFEVFGLVFVLFLLSLRLDITVVKKCGKLAVVIGLASFLVPTVITTLIASYLRGFFKLELHEEVHVVAVIISTTSFHVVFSILEDLKLLNSELGRLALSSSMVSGLFSWSFIVFLANFKEASKLGSKKGIILAQITRIPMIMIIVFAFRPMMWWMVRRTPEGQPLKQSYILIISTMVLFCGFLGEINGHHFLFGPLVLGLATPDNPQLHSCLMEKIGTFVNSFLVPCFLVDVGRGINLFLATFKHVAFALMLVFISTLTKLSAIIATSLYYKMPFRDALSLGLILNCKGFVDALLYNAANKFEGLKTELFSILVVTAMLQSVFVTLLVRLLYDPSRRYIAYKPRTIQNTGLRSELQIVACLHQQDDVRSIINVLEATNPTRASPIAVYVLNLKKLIEGALPLFISHRLNNISSAEKIDIVSNAFYQFEQQNQGLVTVQCFTSFAPYATMHDDVCTMVLEKSTSLVIVPFQRYDSPSMRAVNRNILVKAPCSVALLVNRGNLDRYILSGRLTMKVCVVFIGGADDRETLAYAQRMSGHPNIRLIVLRLVSVDQTFTDLIEKRRNSNMINEFRLNNNDCPRVSYKEEMVRHGNDTVRLLGAMCNDFDLIMVGRRHDPDSTQLIGLSEWGEIDQDLGVIGDIMASKDFECKASILVVQQQASVVVEMIQNQKYVSIYNSDR
The following text describes a protein:
Function:
Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle pole. Note=Uniformly distributed along each microtubule bundle of spindles in addition to centrioles during mitosis, expression promptly diminishes at interphase.
Domain:
The KEN box is required for the association with the APC/C-Cdh1 complex, ubiquitination and degradation.
Sequence:
MVGPGPTAAAAVEERQRKLQEYLAAKGKLKSQNTKPYLKSKNNCQNQPPSKSTIRPKNDVTNHVVLPVKPKRSISIKLQPRPPNTAGSQKPKLEPPKLLGKRLTSECVSSNPYSKPSSKSFQQCEAGSSTTGELSRKPVGSLNIEQLKTTKQQLTDQGNGKCIDFMNNIHVENESLDNFLKETNKENLLDILTEPERKPDPKLYTRSKPKTDSYNQTKNSLVPKQALGKSSVNSAVLKDRVNKQFVGETQSRTFPVKSQQLSRGADLARPGVKPSRTVPSHFIRTLSKVQSSKKPVVKNIKDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQVCIPQTSCVLQKSKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDSKLKKAVPQNHFLNKTAPKTQADVTTVNGTQTNPNIKKKATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLELSSKINNTLTECLNLIEGGVPSNEILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIGLYEEAIKNGATPIQELRKVVLNILQDSNRTTEGITSDSLVAETSITSVEELAKKMESVKSCLSPKEREQVTATPRIAKAEQHNYPGIKLQIGPIPRINGMPEVQDMKFITPVRRSSRIERAVSRYPEMLQEHDLVVASLDELLEVEETKCFIFRRNEALPVTLGFQTPES
The following text describes a protein:
Function:
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
Subcellular Localization:
Nucleus.
Sequence:
MSINREIANVKAFFTSIQLHLSDEWLKSCVNWCREEVLGRHYTFEDLRSKVYEQWLVLDLRDAPIAILPSNLSSKQNFTLNGSFCLQMMQLVDISKPKLWQLQKIRNSNVLTRGTQQDADVAGTGKRLLQMTLTDGIQEIEAMEYKPINCLSLNLAPGTKVRIVGPVMIRSGYLMLETKNVKILGGDVEELSVSHAAENVLARFLKLPENPTPKAIEEKILCVERGEETNEGYVSNVTLPKNVAKKRNLNEDEDIFALPKTDYKNNVAKKLEDDEMAKEIDIMMEVEAELNQENCQIKQKVDERNDDDDDVFASLDIDAHLDQVDAIFNTNSEPIPISKLSENRENNTTHKIKAKFKSVIEKLTFAENEYKLVIEVEDASGTLKVRLHSDVIANFAQCSPSEFSSLKNSITSPDDAAVEKVMKVVIQVKNKLLELDDVMSVQLEKNRTPLVTKIS