lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPVLFVPGNAGSYQQVRSIGSVLFRKADFQRLPHHFDVFAVDFRDELSGLYGGHLAEQTDFLHECVKKIRHLYRSTNASLVILGHSMGGVVARALFTLPQFDAASVSLIFTYATPHKTAAVLDSHLQSFYGRLHETWSRDRGKFTDLTVVSIGGGDRDVLVRTELTTLPAHEGDVSATSTAVPAVWASTDHLSIVWCQQLVVVTARALYDLVVKGQNRLTTDPELIREVVRFHFVRQPYGKQLPQHAPPELVRFGQGGEWSEKLEASWRFRKNKVLSVQSVVMPFYDNESIVVVETGLLTTDPDLIREVVRFHFVRQPYGKQLPQHAPPELVRFGQGGEWSEKLEASWRFRKNKVVVVGERYKRSLRTRRLEVPSALSSFFGPPPTLLSVPLTEGAAFYNLTLSGFRHLWQAYDVTLASKVCRAGTKGEGIVRFVVPWSQEDRFFSIKYPQSKLSRAQTEMPLKIQNPLSEEDSRRFPGVQLHLYLDPECNYVMTAQFSFQRALGQAVKRYITMVPAYLVALMLAALSAQLCSISDTGLCLPFDRALNLASTFPALVLLPAFFECILWPLVSMVWPEPDNAGSSGFLENLALRTGLYSAAYGLTATLGLAFTGVVVLSGHLLTKVETINRYQTKPLPAPKDMSWSKSTLSVVLVLFVVAILTATAVSLVLGYLIYGFKVALLCGQQRMLEDRRGKSGPTSGWRLHVTILMLWACVMLVAMPSFLVWARGLGFFLRLADDPHLAYTAAILAASGVVWQAGVPLTHRFYYKASHCCIYGMAVLTVLYSTVTLYRIAYAASAAHAALALQQALGRDSSVKTV
The following text describes a protein:
Function:
Provides the (R)-glutamate required for cell wall biosynthesis.
Sequence:
MNSPLAPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLTIPEIRAHALAIGDDLVGRGVKALVIACNSASSACLRDARERYQVPVVEVILPAVRRAVAATRNGRIGVIGTRATITSHAYQDAFAAARDTEITAVACPRFVDFVERGVTSGRQVLGLAQGYLEPLQRAEVDTLVLGCTHYPLLSGLIQLAMGENVTLVSSAEETAKEVVRVLTEIDLLRPHDAPPATRIFEATGDPEAFTKLAARFLGPVLGGVQPVHPSRIH
The following text describes a protein:
Function:
Major hexose transporter. Mediates an active uptake of hexoses, by sugar/hydrogen symport. Can transport glucose, 3-O-methylglucose, fructose, xylose, mannose, galactose, fucose, 2-deoxyglucose and arabinose. Confers sensitivity to galactose in seedlings.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MPAGGFVVGDGQKAYPGKLTPFVLFTCVVAAMGGLIFGYDIGISGGVTSMPSFLKRFFPSVYRKQQEDASTNQYCQYDSPTLTMFTSSLYLAALISSLVASTVTRKFGRRLSMLFGGILFCAGALINGFAKHVWMLIVGRILLGFGIGFANQAVPLYLSEMAPYKYRGALNIGFQLSITIGILVAEVLNYFFAKIKGGWGWRLSLGGAVVPALIITIGSLVLPDTPNSMIERGQHEEAKTKLRRIRGVDDVSQEFDDLVAASKESQSIEHPWRNLLRRKYRPHLTMAVMIPFFQQLTGINVIMFYAPVLFNTIGFTTDASLMSAVVTGSVNVAATLVSIYGVDRWGRRFLFLEGGTQMLICQAVVAACIGAKFGVDGTPGELPKWYAIVVVTFICIYVAGFAWSWGPLGWLVPSEIFPLEIRSAAQSITVSVNMIFTFIIAQIFLTMLCHLKFGLFLVFAFFVVVMSIFVYIFLPETKGIPIEEMGQVWRSHWYWSRFVEDGEYGNALEMGKNSNQAGTKHV
The following text describes a protein:
Function:
Has no detectable activity towards cis-acontiate or cis-homoaconitate.
Miscellaneous:
MISCELLANEOUS: The fermenting yeast S.cerevisiae has 2 aconitases, ACO1 essential for the citric acid cycle, and ACO2 specifically and exclusively contributing to lysine biosynthesis. In contrast, in respiring filamentous fungi the ACO2 homologs (acoB) seem enzymatically inactive and the ACO1 homolog (acoA) is solely responsible for these functions.
Subcellular Localization:
Mitochondrion.
Sequence:
MVRQLVWQRATASRRLAPKCLSPQQLFARRGLATEASAARMPPYPKIVRNLEQVRKVLGSSRALTLAEKILYAHLDNAEESLLTGTNNGKDIRGKANLKLKPDRVAMQDASAQMALLQFMSCGLPSTAVPASIHCDHMIVGERGADTDLPASIEGNREVFDFLESAAKRYGIEFWPPGAGIIHQSVLENYAAPGLMMLGTDSHTPNAGGLGAIAIGVGGADAVDALVDAPWELKAPRILGVRLEGRLSGWASPKDIILHLAGKLTVRGGTGYVIEYHGPGVETLSCTGMATCCNMGAEVGATTSVFPFSPSMVPYLQATHRGHVAQAAAEIAASGPKNLLRADDGAEYDQLITIDLSTLEPHVNGPFTPDLSVRLSDFANTVRENKWPETLGAGLIGSCTNSSYEDMTRAEDLVKQASAAGLKPKADFFITPGSEQIRATLDRDQTLASFSEAGGTVLANACGPCIGQWKRTDGVAKGEDNAIFTSYNRNFPGRNDGNRRTMNFLASPEIVTALAYSGSTTFNPMTDTLKTPSGEEFKFRPPQGSDLPSAGFADGNPALQPSAGVPDASVEVIVSPTSERLALLEPFAPFPEGELSGLKVLYKVKGQCTTDTISAAGPWLKYKGHLPNISANTLIGAVNAATGETNVAYDDAGNKHSIPDLAARWKADGIEWLVVAEDNYGEGSAREHAALQPRYLGGRIIVAKSFARIHETNLKKQGVVPLTFADKADYDRIDACDQVDTVGLYETLQSGGQGSIQLQVTKKSGEKLTIPVNHTLSKDQCGFILAGSALNLLAKRAHQ
The following text describes a protein:
Function:
Heme-containing cytochrome P450 probably involved in the biosynthesis of xanthophylls. Hydroxylates beta-rings of alpha-carotene. May also have activity on beta-rings of beta-carotene.
Subcellular Localization:
Plastid, chloroplast membrane.
Sequence:
MVAAMAFPAAATYPTHFQGGALHLGRTDHCLFGFYPQTISSVNSRRASVSIKCQSTEPKTNGNILDNASNLLTNFLSGGSLGSMPTAEGSVSDLFGKPLFLSLYDWFLEHGGIYKLAFGPKAFVVISDPIIARHVLRENAFSYDKGVLAEILEPIMGKGLIPADLDTWKLRRRAITPAFHKLYLEAMVKVFSDCSEKMILKSEKLIREKETSSGEDTIELDLEAEFSSLALDIIGLSVFNYDFGSVTKESPVIKAVYGTLFEAEHRSTFYFPYWNFPPARWIVPRQRKFQSDLKIINDCLDGLIQNAKETRQETDVEKLQERDYTNLKDASLLRFLVDMRGVDIDDRQLRDDLMTMLIAGHETTAAVLTWAVFLLSQNPEKIRKAQAEIDAVLGQGPPTYESMKKLEYIRLIVVEVLRLFPQPPLLIRRTLKPETLPGGHKGEKEGHKVPKGTDIFISVYNLHRSPYFWDNPHDFEPERFLRTKESNGIEGWAGFDPSRSPGALYPNEIIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQKFDVELRGTPESVELVSGATIHAKNGMWCKLKRRSK
The following text describes a protein:
Function:
Plays an olfactory role that is not restricted to pheromone sensitivity.
Subcellular Localization:
Cell membrane.
Sequence:
MTTTPAFAIVSKKKRVVKLCCLGVLFLTLAYAVIVIDPTEVIVEDKLSMYEGSYLNRLWKKPPLEVFISIYVFNVTNPVAFMRGEERLRVQEIGPYVYQEFLEHRNSTFNQNGTLSFVPVRRQVFVPERSVGDPKQDRIMIPNIALLGVSSAAYRMSTFAAFAVAAALKPLGMSPILNITTHDLLWGYDDPLVRIASTLLPDIIHFQKLGVLDRMFDDGFDTVTINLPQSVHNQRHDAEIDILPEDISDDLIVGLEEEYYHDLISRSTTEELIRDYSIDVWNGSPGLAHWGYVAKDHWDANRRNTPCNTLQGSYDGSVFPRNISKTEVFKVYRKAFCRTLPIAFEREGEVDGIKAYWFSIKENAFESSMDDPYTSCYCKNNRCLPKGLGDLSPCWYNIPVAVSLPHFYKGDPSLSQAIDGLSPNKEKHDAVIIMQPQLGIPMKANIRVQISLLTNVSFNSELRPFHNTVIPLIWAEMSLEKLTPELILLLNLLFGIAPYLQTGFVCVLALLGASLIATAALVLLCSSDATTFEYDPRKSIRYSTVNIIPYPLRKELDKYGETEVIRREPLLIENVA
The following text describes a protein:
Function:
Secreted L-amino-acid oxidase that acts as a key immunoregulator. Has preference for L-aromatic amino acids: converts phenylalanine (Phe), tyrosine (Tyr) and tryptophan (Trp) to phenylpyruvic acid (PP), hydroxyphenylpyruvic acid (HPP), and indole-3-pyruvic acid (I3P), respectively. Also has weak L-arginine oxidase activity. Acts as a negative regulator of anti-tumor immunity by mediating Trp degradation via an indole pyruvate pathway that activates the transcription factor AHR. IL4I1-mediated Trp catabolism generates I3P, giving rise to indole metabolites (indole-3-acetic acid (IAA) and indole-3-aldehyde (I3A)) and kynurenic acid, which act as ligands for AHR, a ligand-activated transcription factor that plays important roles in immunity and cancer. AHR activation by indoles following IL4I1-mediated Trp degradation enhances tumor progression by promoting cancer cell motility and suppressing adaptive immunity. Also has an immunoregulatory function in some immune cells, probably by mediating Trp degradation and promoting downstream AHR activation: inhibits T-cell activation and proliferation, promotes the differentiation of naive CD4(+) T-cells into FOXP3(+) regulatory T-cells (Treg) and regulates the development and function of B-cells. Also regulates M2 macrophage polarization by inhibiting T-cell activation (By similarity). Also has antibacterial properties by inhibiting growth of Gram negative and Gram positive bacteria through the production of NH4(+) and H2O2.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: Uses the promoter of the upstream NUP62 gene and shares the first 2 non-coding exons with NUP62.
Subcellular Localization:
Secreted. Lysosome. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Secreted at the immunological synapse.
Sequence:
MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQPPALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MPSFDSSVLLFREVGKGIQLGTGRTWVFQRAKEGLLCTYNPFTSEYWRGLGGVLFLSLWGRWLTLIYKVFESSISPLLCSEMDCEFRLDLCSKGHRKESDKSRSRKDDDSLAEASHSKKTVKKVVVVEQNGSFQVKIPKNFVCEHCFGAFRSSYHLKRHILIHTGEKPFECDICDMRFIQKYHLERHKRVHSGEKPYQCERCHQCFSRTDRLLRHKRMCQGCQSKTSDGQFSL
The following text describes a protein:
Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAGSLFRSEEMCLTQIILQVEAAYCCIAELGELGLVQFRDLNAHVNSFQRKYVNEVRRCETLERILRFLEKQMELEQVVAENCGESCPLSPLPREVHDLESVLEKLESELLGMAQNQQSLRSNAMELIELKELVKTVQEFFEKETHFPDEFFTEENTALVESHGPSTAVASGKLGIIGGVIRSERMLSFERVLWRVCRGNVYIKQRDMDATVEDPDTKEEVKKKVFFIFFQGEQLGLKIKKICQGFHATVYPCPENSKERRETAASINCQLEDLQAVLKQAGDHQKRVLQEAASSIQEWKIKVQKMKAVYHTLNMCNIDVTQQCLIAETWCPVTDMDRIKTALQKGMDRSGSTVDPIVTEVSTRMSPPTFNRTNKFTAGFQNIVDAYGVSTYREINPAPYTIITFPFLFAVMFGDWGHGVIMLSFALLMIHNEKMFSKKKSNNEIWNTFFGGRYLILLMGIFSIYTGFIYNDCFAKSFNLFGSSWHVRPMFLNGTWNAHILEGSLLLQLDPAVPGVYSGSPYAFGIDPIWNIASNKLTFLNSYKMKMSVVLGIIQMIFGVILSLFNHMHFKNTVNIVFQFIPEIIFITCLFGYMVFMIIFKWCQYDVHSSQIAPSILIHYINMFLFNYGDSSNAPLYSYQQEVQSFLVVLAVIAVPWMLLFKPLILRAKHLKSQQQLIKGGREEIEVDILHVHSSNDTPPEGREEGEREVHQSVSENTEQIEMDKLQTHSSINSGGHNEIHDEGQKEFNFGDVFVNQSIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWHMVIHIGLANRSWGGVIGVFVIFSAFAVLTVAILLVMEGLSAFLHALRLHWVEFQNKFYTGTGYNFSPFDFKHVLSGSEED
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.
Sequence:
MEKTKQRAGLSSPPSRLFQLRDFLLVYNRMTELCFRRCVPGLLQRGLDGSEESCLEGCAGKLVRSNQRLMAAYVRLMPALVQRRLVLDSNSQHSSQPQAPSFSPSAA
The following text describes a protein:
Function:
Can convert acyl and alkyl dihydroxyacetone-phosphate (DHAP) into glycerolipids and ether lipids, respectively. Required for the biosynthesis of phosphatidic acid via the DHAP pathway, where it reduces 1-acyl DHAP to lysophosphatidic acid (LPA). Also has triacylglycerol (TAG) lipase activity. Involved in the mobilization of the non-polar storage lipids triacylglycerols (TAGs) from lipid particles by hydrolysis of TAGs. Lipolysis of TAG by AYR1 is essential for starvation-induced autophagy. Forms an NADPH-regulated cation-selective channel in the mitochondrial outer membrane.
Subcellular Localization:
Lipid droplet. Cytoplasm. Vacuole. Endoplasmic reticulum. Golgi apparatus. Mitochondrion outer membrane.
Sequence:
MEAEKFVLITGCSEGGIGNALALKFHQEGFQVLATARQVERMDNLTKAGLQTLKLDVTDEDSVREVEQEVRKFTNGSLHYLINNAGAPCSAPAIDLDIEDVSKVMDVNFYGVIRMNKAFQHQLIRAKGTIVNVNSLVSYVPFAFNAAYNASKAALLAYSNTLRIELAPFGVQVTSIMTGGVQTKIQSKPLGTMTEAAIPENSIYYPYRKLILENRNPVEKFVTIEEFADAAYPQLVGRGRWYQLFKPGVRPAQIWAGYMSSAGRVGSMLPVEVFSMSVRLIVKLPSTAVWRDHTVD
The following text describes a protein:
Function:
Helicase with 3'-5' helicase activity involved in genome stability. Functions in the RAD4-dependent nucleotide excision repair (NER) pathway and plays a critical role in DNA interstrand cross-link repair. Unwinds relatively long duplex DNA up to 120-bp and requires a long 3'-tail of at least 70 nucleotides for efficient unwinding of duplex DNA. Activity is significantly stimulated by a preexisting fork structure. Shows both processive helicase and DNA strand annealing activities. Affects telomere length by a non-catalytic mechanism, probably through inhibiting telomerase by competing with it for ssDNA binding.
Miscellaneous:
MISCELLANEOUS: Present with 259 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MEEGPIKKKLKSAGQGSGKTDAFRNFEQFFFRLNTLYTFLICRKHVVPTFKTLCGPIETALKRTVTKEDLAMVMALMPRECVFKYIDENQIYTETKIFDFNNGGFQQKENDIFELKDVDDQNQTQKSTQLLIFEFIDGTMQRSWSASDRFSQIKIPTYTTEEMKKMISKREALFKSRLREFILEKEKANLDPFSELTNLAQKYIPRERDYEDPIEAMMKAKQESNEMSIPNYSNNSVITTIPQMIEKLKSTEFYASQIKHCFTIPSRTAKYKGLCFELAPEVYQGMEHENFYSHQADAINSLHQGENVIITTSTSSGKSLIYQLAAIDLLLKDPESTFMYIFPTKALAQDQKRAFKVILSKIPELKNAVVDTYDGDTEPEERAYIRKNARVIFTNPDMIHTSILPNHANWRHFLYHLKLVVVDELHIYKGLFGSHVALVMRRLLRLCHCFYENSGLQFISCSATLKSPVQHMKDMFGINEVTLIHEDGSPTGAKHLVVWNPPILPQHERKRENFIRESAKILVQLILNNVRTIAFCYVRRVCELLMKEVRNIFIETGREDLVTEVMSYRGGYSASDRRKIEREMFHGNLKAVISTNALELGIDIGGLDAVLMCGFPLSMANFHQQSGRAGRRNNDSLTLVVASDSPVDQHYVAHPESLLEVNNFESYQDLVLDFNNILILEGHIQCAAFELPINFERDKQYFTESHLRKICVERLHHNQDGYHASNRFLPWPSKCVSLRGGEEDQFAVVDITNGRNIIIEEIEASRTSFTLYDGGIFIHQGYPYLVKEFNPDERYAKVQRVDVDWVTNQRDFTDVDPQEIELIRSLRNSDVPVYFGKIKTTIIVFGFFKVDKYKRIIDAIETHNPPVIINSKGLWIDMPKYALEICQKKQLNVAGAIHGAQHAIMGMLPRFIVAGVDEIQTECKAPEKEFAERQTKRKRPARLIFYDSKGGKYGSGLCVKAFEHIDDIIESSLRRIEECPCSDGCPDCVAASFCKENSLVLSKPGAQVVLHCILGHSEDSFIDLIKDGPEPNMPEIKVETVIPVSEHVNFSDDFKIIDVRRATKDDTHTNEIIKKEI
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MYSYKKISYQMEEVMSMIFHGMKLVKSLESSLPEKPPESLLTSLDEIVKTFSDANERLKMLLEIKNSETALNKTKPVIVSVANQMLMQMEPGLMQEYWLRYGGSTSSQGTEAMFQTQLMAVDGGGERNLTAAVERSGASGSSTPRQRRRKDEGEEQTVLVAALRTGNTDLPPDDNHTWRKYGQKEILGSRFPRAYYRCTHQKLYNCPAKKQVQRLNDDPFTFRVTYRGSHTCYNSTAPTASSATPSTIPISSVTTGHSVDYGLAVVDMADVMFGSGGVGTNMDFIFPKNDPS
The following text describes a protein:
Function:
Transcription factor involved in the expression of defense genes in innate immune response of plants. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Activates WRKY 29, SIRK and its own promoters.
Miscellaneous:
MISCELLANEOUS: Acts downstream a MAPK cascade and therefore might be regulated by phosphorylation. WRKY 22 and WRKY 29 may provide redundant functions.
Subcellular Localization:
Nucleus.
Sequence:
MADDWDLHAVVRGCSAVSSSATTTVYSPGVSSHTNPIFTVGRQSNAVSFGEIRDLYTPFTQESVVSSFSCINYPEEPRKPQNQKRPLSLSASSGSVTSKPSGSNTSRSKRRKIQHKKVCHVAAEALNSDVWAWRKYGQKPIKGSPYPRGYYRCSTSKGCLARKQVERNRSDPKMFIVTYTAEHNHPAPTHRNSLAGSTRQKPSDQQTSKSPTTTIATYSSSPVTSADEFVLPVEDHLAVGDLDGEEDLLSLSDTVVSDDFFDGLEEFAAGDSFSGNSAPASFDLSWVVNSAATTTGGI
The following text describes a protein:
Function:
Probable transcription factor, involved in regulation of dopamine neuron lineage specification. May play a role in maintaining robustness of the Wnt/beta-catenin asymmetry pathway.
Domain:
Third 'degenerate' zinc-finger domain essential for function.
Sequence:
MGPDTTSERVSEDLMQAVTCLKRVMVGMKSNGTDYVQEQTPSNSTTVICTLVKITGALERCIESNKAMNDVLNGKMKCTTCGATSVGLLSDCHDSATSTTTTVSHRSSEEPPRRKPSAAGGDHDDEELECSSIESRSIRSVSSSVHTSAEDDETNQTMMVPTDVADVINAIVAGTNGSSNSNTTSSSKSPQEEEEEHDLVMKSILSTTTSTSNTKLELSEKLENPLQDTALLDQFLQASLLGQTPTVTPASEENEEDKEQNAVLTSFLQILFANQQAGNAILDAGSSENDGSTSSSQPSPPADPTASLDSLAMFESLLAESMNGNVLDANTSSADQKAAARKRKSTPMKVPKSENGAGYICPMDGCNKVFKEKGSVHRHFVTHIGMRFNCDKCKASYTQKHALMLHQKIHANPDAYQCRGCGTNYTTQNGLRLHRQRNPACMEVSNALEFNTSLNTSISEALSGPLSKNSSPTKQMVSAP
The following text describes a protein:
Function:
Involved in the transport of maltose and maltodextrins. Indispensable for translocation of maltodextrins (alpha 1-4 linked polyglucosyls) containing more than three glucosyl moieties. A hydrophobic path ('greasy slide') of aromatic residues serves to guide and select the sugars for transport through the channel. Also acts as a receptor for several bacteriophages including lambda. Binds maltosaccharides; when LamB binds starch in soft agar, it inhibits motility.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEATDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVGFGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDYGRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSGVAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVGIRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFATYAKWDEKWGYDYTGNADNNANFGKAVPADFNGGSFGRGDSDEWTFGAQMEIWW
The following text describes a protein:
Function:
Binds 16S rRNA, required for the assembly of 30S particles.
Sequence:
MGKYKPPAERKYGKGVQSCQRCGSKDSVIQKYGIYLCRQCFREVAYELGFRKYW
The following text describes a protein:
Function:
Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.
Sequence:
MHPSTSSTSSATTAAAAAPGTKCTPITADDSIVISGIAGKYPRSDSVEHFADNLYNKVDLVDDKEDRWRHLYAGIPKRLGKLNKLGKFDAEFFGSGFQETHTMDPQQRLLLEHCYEALLDAGLHPDDIRGTRTGVFVGVSIAETEIYWTYKKTKSPYNRSILGFVRSMLATKIAYALDLKGPSMAVDTACSSSMYALDWACKAIRQGQCDAAIVAGTNLTLHPYITLQFALLGVLAADGYCRPFDKNASGYSRSEANAVILLQKAKDAKRIYAHVVNTKTNCDGYKLEGITFPSNKIQKQLLDELYSEVPYDPKDISYVEAHSTGTVVGDPEECDAIEKVFCPDRTEPLLVGSVKSNIGHSEAAAGICSVTKCVIAMQNRIIPPNINYTEPRTDVPSLLNGKLKVVDQCTPLGGPLVAVNSFGFGGANAHALLHNCTKQKINGGYPKDGLPRLVVWSGRTIEAVDHFLDSLKGKSYDAEFYALTHNIQRSEIPKMTTKGYAIFGGRQDGTAELLYKAASNKIPKKYKLPPVTLAFGQLEGNWKATVQAFNQFPEFANGIAECLQAIKDCGFDAFDQTMQANDPIQHILWTFMAQVGVYRLLTASGVTIDQYAGYAVGQITCAYLDGVLSLHDALRVAYAHGYIIRAHHTEKSANYGSGVSSNKQLTVKLATALKPLRLQAATPKWFNPCQLKTFEMYDPKVMTTLFHTLGANEAIVLQPLNASKDVLMHFLKSLGEVFLKGHPVNLLPVYPAIQFPVSQGTGMISSLLEWDHSADWHVTNFRTTRMVDQSTSEYTISLSEQDYISGHCIDGRILIPATGYLFYVWDSFSGRMGIIPEEMPVEFSDIEFLRATTLVGDQQVTLTVDLNEVTGSFEVSEGTALVVKGRIQALTNYTPPETKHRQSDAVMMPSKDFYKELRLRGYHYGGYFKSVMESRTDGSYAKIEWKYNWTALLDCILQVAIIAVDSRSLVIPTRIESIKIDPIQHKLTDQATGNEVPSYNVCFDPDLNLLQCGAIEIRGLNASTIARRLPPGVPVLESYKFHPYYPQHTMAPSSAVSTIVQTILENQATIFFTVTEIHSKTKDPIISLFGDAIGDLPLVKAHLTLLSTAKPEPIPNVTISEDKLMKQRNVLLLICENLFADDEFISDAINCLSDQGFILLRESPEYRLQDGHRRLQLVSTMSIEGETFLLLQQKKSAMNTSVDAHVIKVCSNDTTHNWLLELKQEVKTKPIILYAQNDPSSGIIGLVNCIRKEPNIQTVSCFFIDDPSAPAFDASNPFYKEQIELGLAINVYRKGQWGSYRHFKLQEEPRYEPATKHCFANCVKPGDLSSFTWMVGPLSEQPPSSPLARVVYSSLNFKDVMIATGRLTVETFCTDRLQQECILGFEYSGVTTTGKRVMGIIGAGSMATIVESDPIFTLDVPDNISLEQAATIPTVYTTVYASFFVCAQIRKGNSILIHAGTGGVGLAAIRVCLAYGLEVFTTVSTKEKRDFLLSYFPDLNPNNIGNSRDISFETLIKERTNGRGVDFVLNSLSEEKLQASIRCLARGGHFLEIGKYDMMKDSKIAMTFFQRGITFTAVLVDLLFQEKRDLLVELHKLIMKDLAKGIIQPLPTTVFQAHEIEQAFRYLATAKHIGKVVLKIRDNEDDLASVPISYLPRVYCNPEQTFVIAGGLGGFGLELADWLIIRGCRKLLLSSSRGITKPYQQYRINTWRTYGVQVTVSTEDISTYDGCRRLLQQAIQMGPIAGIFNLAVQLRDAIIENQSVDKFAECLAPKATATHHLDALSRELCPMLKHFVVFSSVSCGRGNAGQSNYGMANSIMERIIEHRVVHGLPGKAIQWGAIGEVGIVADMQEDKIDMEIGGTLQQRLSSCIQVLDQLLTTSEPIVASMVVAEKRSSSGGAKNIVEAVMNIMNIRDMKSVSVESTLADIGMDSLMAVEIRQVLERDFDIILTPQDLRTLTFSKLQKLADAKTESETAEATTQQLQLQDLLASFGDETASHHTVLRLPSKCNDLEYDRPVLIIPGIESVSSPAWTKIASEINAPTFVLQTFAKGSDEQTIPGIVDSVFEEMFETVFAKAEQFLVIGYSFGALLALEVVKRLEARPLRGKLMLIDGSPLYLQRFASHHLSGFDDEHLQMAILTLVLRFSLPSVSNEILSSIMGEATYENRVTKMLDIGRESNPFSEEYTRKMMRVLLFRLKAAMNMSTEVKEKLASPLVLVRSGTIGDIEEDYGLTEFTSSSMIVKIIDGTHQTMLANMELLEIINKDTL
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MKKVNWDEINRFIKNDCSQVISYGFNPYDFAVENWNNGTNAGFNVDDLLRQSRTFALQIADEYAVPLEVNAKTYTKKAELRKEIDDFLAAKNRVIEKTRARFTIDPEDLKQKWLKTVKLEKEIELFEQVENLVTVSPIVYSKIEQGKHDEAVRHICEELQIYSDRNFHQIESLDSVKEGIDKARSDMVGHVMNSLFSLLFIKQRLPGISFFRPYPHSEIRIPRVDTSQIEEYTILLICLEIQNDFFTQLRETVRDRLALLMSETAESIKVQKIRQFAQSKDGFEELVDIANNYNMSHPLVMFIDQLLSKMWVLMSRCKAFDQVFSVENTNGVAFANAYAAVDELIRDIVTAFTSVQGSITMYTANKLSYKFLSSETAHQNSTASQLRSELGIKPCSANSLHIFMMLDDFNSCLKEKYNISYSQLSNKMTIDLDVKKIFADQTKLISDSIDVSRPVKIEAHPVPVLISTPLLLDNIEKYGKIAGRFTYLQDMIIGFMIQFLKAFISRCLNEIGHVKSAESQEQILSSRILTSDKDIVLKYLGKVITTELVLKDNMGDYEDNIKDLSQMEEQNELDLVDKSQPLTIENTIREKFCLPTIAATAESIVVIKNSIESLLISQKYTDSNNSAIRSLITELEQTLVRAMIFIRLEMRCRTYVDIIQPLLNGNYTPLSSPTKPDQYVTDFISTYNSSTDNIGNCLTPARNSFVFIGIARLVYNIHIRYGPRIREISDKGAAQLTMNLSALNQHLSSIQYPEQSIYKKTLVFVSNISYSTDRILMQIAQQKDLFTYEEMEPVFNMQQKMNEHHAENLDKLRQLLKK
The following text describes a protein:
Function:
Required for arabinosylation of arabinogalactan (AG), an essential component of the mycobacterial cell wall. Probably acts as an anchor protein recruiting AftA, the first arabinosyl transferase involved in AG biosynthesis.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MRFVVTGGLAGIVDFGLYVVLYKVAGLQVDLSKAISFIVGTITAYLINRRWTFQAEPSTARFVAVMLLYGITFAVQVGLNHLCLALLHYRAWAIPVAFVIAQGTATVINFIVQRAVIFRIR
The following text describes a protein:
Function:
Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest. Binds to the consensus sequence 5'-CCCG[GT]ATGT-3'.
Subcellular Localization:
Nucleus.
Sequence:
MNTGDVPATVTLESVNSVTFTQDTDGNIILHCPQNDGEDLGSDETTEPVHKRIRLSSEDGEDPQDSASTEYSVVTLPITDGDESFEVTMTATEMRDEELESDDLSETTGKDSSAQKKGEDVSAVSQAWFTTKEDKDTLVNKGHKWKQGMWSKEEIDLLMTNIELYLKNRGIQDPAEIIFEMSKEERKDFYRSIACGLNRPLFAVYRRVLRMYDNRNHVGKYTDEEINKLKELRQKHGNDWATIGSALGRSASSVKDRCRLMKDTCNTGKWTEEEERRLAEVVHELTGTEAGDVVTQGVSWASVAELVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDDINLVRRIAELEVEDENEINWDILASGWSSVRSPQWLRSKWWTIKRQVANHKELPFPVLLKGLQDVVEAPPSTMNKVVVVGSRSANASPSPVTALQIPVQIPVQITHVSSSDGSSGTSDSETITLNSGALQTFELLPSFHLQPTGTPGTYFLQTGTNQSLPLTLSANPTVTLTAAASPSSPDQIILHSLTTDTENVTVQMSHPGIIIQTVTSEDLADPLGQSELEGEQVLVKEEPSENQTNPAIEEPSEEQSKQGEKTLDSSKVVETVLMVPSPGSFIPTNEDISSDSVLPLGTLTDPILENQEEGSN
The following text describes a protein:
Function:
Maleamate amidase that transforms maleamate into maleate and ammonia in the aerobic nicotinate degradation pathway.
Sequence:
MSDAQSARDNYQGVWGQRIGFGRKPALLMIDFMQGYTTPGAPLYAPGVVAAVEQAAGLLALARDCGTLVVHTNIRYQPPHFADGGVWVRKAPVMKDMVEGNPLAAFCEAVAPQAGEVVLSKQYASAFFATSLAPLLHAQGVDTVVLAGCSTSGCIRASAVDAMQHGFRTIVVRECVGDRHSDPHEANLFDIDSKYGDVVTRQDAMQQLRHLAG
The following text describes a protein:
Function:
Multidrug efflux pump that functions as a Na(+)/drug antiporter. Confers resistance to norfloxacin, acriflavine, doxorubicin, ethidium bromide, tetraphenylphosphonium chloride, daunomycin, berberine and sodium deoxycholate.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MNFRLLSQYHADIKKLIKISLPILLAQIAQNSMGLADTIMAGRVSSTDMAAISIGASIWMPLMFFGQGLLLALPPTISYLNGSGQHHRIAHQVRQGIWLVLGVSIPLGLLIYFCEIPLQYMQMESKMSDLARDYLHAMLWGLPAYLMLINFRCLNDGIEKTKPAMVITFLGLLINIPLNYIFIYGKFGMPAFGAVGCGIATAIVNWAMCLMMIFYSYTNTQERSLKVFSQLIEMPNPKTLKKLLRLGLPIAIAICCEVALYALTSLMLSPLGATIVASHQITLNTSSFIFMFPMSIGMATTILVGQALGAGSPQNAKKIGYAALLLGLTVTIVTALITIFFRYEIASIFVTDEIVIAMAANLLLFAALYQFSDTIQMVVGGILRGYKDTKVILYITLFSYWVIGVPLGYTLGRTDWLVPHIDAKGFWIAFVVSLTFAAFLLSLRMKKMQAMNDNAILQRLEKLK