lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTALLELCNVSRSYPSGEEQVAVLKDISLQIHAGEMVAIVGVSGSGKSTLMNILGCLDKPTSGTYRVAGRDVSTLDPDALAQLRREHFGFIFQRYHLLSHLTAAQNVEIPAVYAGIERKKRQARARELLLRLGLSDRVDYPPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILRQLRDRGHTVIIVTHDPLIAAQAERIIEIHDGKIVHNPPAQEKKREQGVDAAVVNTAPGWRQFASSFREALSMAWLAMAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRAMGTNTIDIHPGKDFGDDNPQYRQALKYDDLVAIQKQPWVNSATPSVSKSLRLRYGNIDIAVNANGVSGDYFNVYGMSFREGNTFNAVQQQDRAQVVVLDANTRRQLFPNKANVVGEVVLAGNMPVIVIGVAEEKPSMYGNSNLLQVWLPYSTMSDRIMGQSWLNSITVRVKDGVDSDQAEQQLTRLLTLRHGKKDFFTWNMDSVLKTAEKTTYTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGISLSMFIAFMLQLFLPGWEIGFSLTALASAFLCSTFTGILFGWLPARNAARLDPVDALARE
The following text describes a protein:
Function:
Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors. Inhibits B cell chemotaxis toward CXCL12. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (By similarity).
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
Sequence:
MRAAAISMPRLNKMPGMFFSASPKDSKEHSHSLLDDKKQKKRPKTFGMDVKTYLRSMIPHLESGMKSAKSKDILSAEEVMQWSQSLEKLLANQTGQNVFGRFLKSEFSEENIEFWLACEDYKKTETDLLHNKAENIYKAFVHSDAVKQINIDFHTRESTAKKIKTPTPTSFDEAQKVIYSLMEKDSYPRFLKSNIYLNLLNDLQANTLK
The following text describes a protein:
Function:
Catalytic component of the NuA3 histone acetyltransferase complex, that acetylates H3K14. The NuA3 HAT complex has 2 functionally distinct forms. NuA3a binds H3K4me3, through the PHD finger of YNG1, and acetylates H3K14 at the promoter region of actively transcribed genes to promote transcription initiation. NuA3b binds H3K36me3 at the coding regions of actively transcribed genes, through the PWWP domain of PDP3, and coordinates transcription elongation. In vitro, SAS3 acetylates free histones H3 and H4. It is involved in silencing the HMR locus.
Subcellular Localization:
Nucleus.
Sequence:
MSLTANDESPKPKKNALLKNLEIDDLIHSQFVRSDTNGHRTTRRLFNSDASISHRIRGSVRSDKGLNKIKKGLISQQSKLASENSSQNIVNRDNKMGAVSFPIIEPNIEVSEELKVRIKYDSIKFFNFERLISKSSVIAPLVNKNITSSGPLIGFQRRVNRLKQTWDLATENMEYPYSSDNTPFRDNDSWQWYVPYGGTIKKMKDFSTKRTLPTWEDKIKFLTFLENSKSATYINGNVSLCNHNETDQENEDRKKRKGKVPRIKNKVWFSQIEYIVLRNYEIKPWYTSPFPEHINQNKMVFICEFCLKYMTSRYTFYRHQLKCLTFKPPGNEIYRDGKLSVWEIDGRENVLYCQNLCLLAKCFINSKTLYYDVEPFIFYILTEREDTENHPYQNAAKFHFVGYFSKEKFNSNDYNLSCILTLPIYQRKGYGQFLMEFSYLLSRKESKFGTPEKPLSDLGLLTYRTFWKIKCAEVLLKLRDSARRRSNNKNEDTFQQVSLNDIAKLTGMIPTDVVFGLEQLQVLYRHKTRSLSSLDDFNYIIKIDSWNRIENIYKTWSSKNYPRVKYDKLLWEPIILGPSFGINGMMNLEPTALADEALTNETMAPVISNNTHIENYNNSRAHNKRRRRRRRSSEHKTSKLHVNNIIEPEVPATDFFEDTVSSLTEYMCDYKNTNNDRLIYQAEKRVLESIHDRKGIPRSKFSTETHWELCFTIKNSETPLGNHAARRNDTGISSLEQDEVENDVDTELYVGENAKEDEDEDEDFTLDDDIEDEQISEENDEEEDTYEEDSDDDEDGKRKGQEQDENDIESHIRKERVRKRRKITLIEDDEE
The following text describes a protein:
Function:
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
Subcellular Localization:
Cytoplasm.
Domain:
The VLRF1 domain mediates binding to the 60S ribosomal subunit.
Sequence:
MATGQHFPIADLTAEERHQMRTMRKRKADLLNEIESIKGELHSVEGELENLYYVDDLSKERNSMLSSGRKKFNQDPEAYVDDVQTRNLRSCIDIIIQQGLSYLYERGILERTPQSVASFLYQGGGLSKQTIGEYIGSNEPFNVQVLEEYVKLHDISNLFLVDALRMFLWSFRLPGESQKIERMMAKFADHFHTSSTRDGHAFDCPDTAHVLSYSCIMLNTLLHNPAVKDKPSLERFVAMNKESVQQNGVSVETIAQIYDSIAKQPFKLPDEENSRSHEPFIDSTREGWLYKQSSNQAFVVGPLLWKRRWFILSEGCLYYFDSSIDRAPKGIIPLKNVGVRRVEAPQRPHMLEIYALSPDDKIKACKTDQVGGRVSEGRHSNYRMCAASQDDLIGWIEAIAAQMSRRLSTIRDVRWTAGVEPLKRSKIKEQPEVAAASEVGGASCWSFDEMMKRAEEAQLVLQDGDEESTVSCSSCATRLGAERTQLLEHYASGWHRANVRRSLRGKQPIGEEDWESLVEGSDGEGGERGDVSDSSSDSDCTDEQTSAALGLGAARAYFVQSGTVFSMYSALLRDGEASVASTPSFFSRPLNCAIILLAGGHFAAGVFENDRLVVHRAIHRYVVRAKQGGAQSANDKSKGNAKSAGANLRRYNERVMREEIRGLLAKEWQVYLAAAPLVFLRCASYQRGIFISDDDEDAPLRRGDARLRTIPFETKRPLVDEVRRTWERLAEVQDHGAVEEFEKEMEERRERLRKRATALQRRGRRQEEAPSTFDDEKDLDEEDSRRDEKWRERKERKELAEKEAAEEKAAKDPFPEIDQDLRNSVYAAIRDNDKAGAGLEEVIKGVEEAERKEVLLRYIREARFPPINSSLLHIAAAKGADHSVKYLLDLGANPAMRNAEGKAPYNCAEGKIIKGVFSAWRAEWEEAEEDMEEGEKAKRRQIDWIKAQIPLPVEKSTEQLAREAEKKKAKRDRQRVKAKEKKEEERKEKEEQANKAAYLALPDREKRALAIEARLAKMDSCVPRCFMCAATISGTPFEYAANRFCSTALISFYMRGSTLTRLAGGLSRQMSSSSAAQEAYLDADNCLVVDESDRIVGGATKRQAHHRSTVQLHRAFSVFAFTPDRQLILQKRAATKVTFPLLWTNTCCSHPLTGMRPDETDGVGGVLRAATRKLDHELNLAAVSEDQLLFMGRYLYKAAPPELEWVEHELDYALILRGIDRARVASPNDDEGTVVGILHYCAHDGRSTLTPALFHLQLGESSSVEQVRCVDERELEDWIKKEPTSFTPWIRHFIEIGVLSKWWSVLDDKEKLQKMSSDKIVKMN
The following text describes a protein:
Function:
Gap class segmentation protein that controls development of head structures.
Subcellular Localization:
Nucleus.
Sequence:
MADSTPTLAAHTPLQVPRDTAASDSVFKVAAPWNFLPNQTNLFSSLAEFGAPQPTADYEKKVFEWLPPTPAGDHQTTPTGAWESPSPAAGLLRPQPQKPENGAALPAPSPRSASRSESPIDVVSTSAFSSVDQTSHAKDADAEIVRPQPLRVDSMDASVNPLLILASEQQQQLQPQPIVTLASAFGIPADTVIMSTEPGPSSSAPSEQPSSQSNNVSPPSRGCYTRAPGLGPPPETPTSGNGTASAYVCAVCGFSCASKFHYNSHMNTHGDHQCTMCDYTSRTEGRLKKHMRESHTVEQQIAAGLEVPETHQSSSSTNNSPSKDDGVALPSTDADMSEGTLDIGPSTLSSTLLGMIATSQASQMTSALEQMRAITEQPLLGDGSNEGLLLVGAPLGFVPMKEEGGGGGGGRRKQKVYKCKQCPHLSQTKEDQWAHARSHIPSDKQMSCDKCNFVTEYKHHLEYHQRNHAGIKPFQCKKCAYTCVNKSMLNSHMKSHSNVYQFRCADCNYATKYCHSLKLHLKKYGHRRNTEGMSEADLLQSLSAENSPPSMRKDSTASMSSSLSGPFTPFSALMKREEPTTPLTTPTMPNFGLAQSIPTSQSLSFATQMLLRQHQLQQLMQEPSHKCCMCEFTCGSKEEMLHHNMSHLPQLLSNSNLYQALGVQATLAIPDRSAEDDHHTTTGSPSGDDAVSHSNGSAGSPLGSGRGSSDEGEGGASRRKSKPSRIAIDDIGLQLMDKASPDHTNVSVIKTVEVKQEEPMDTADEPSATVELNSSSEQLVLPLPAPQPLRHQLLQLQQQHPLLLQAQHQEMNGGMPESGALRQAFLNHLMNQHRQQPAELYRYECRHCSMGYSDTNMHRVHMSYHSLDNPLQCSRCGMVCASALHFNLHLLQSNHL
The following text describes a protein:
Function:
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSVQSEIFCQSWIVFFVLDQLSRHSLSLASAIEFDAGVVGMEFLLELEALVIGMESGDLVLVEPRSSSAIEVIGSLQGGILSLAASPDGELLAIVSGLGQILLMTPANWDTVHEFSIKNNDRQEFSSSAVELSWRADGKYFATSEYNAQESSSVVKIWERETGKLHSSCEALPSTHRSSICWSPSGARIAASTSKADQAPSVTIFERNGLKKDYFQVTAPAGARVESLQWDSSGEVMKMVVRCDGWDAIQFWYCSNYHWYLKQEWRYTSKETVSTVWHPEKPLSAMVWTVLGNIKATTLGWKSAVLDSSVALVIDGPSLLVTPLAVCMTPPPLYFSKVRFPAPVNTVTLTSESSGFTTVAASLSDKSFGLAVLATSDGWNDLEDSEVVGYILQNFDGGVRNLISTGANRFCGLLDSSSGHGSLQFTEFEATDSGEGWTSRSLSLVYLDKPLIAAARSPLTESSQAFLQLNDGSILNHCAGELTPVGKFPVACPWMQAFEDKGQVQFVGLDERGQLHFRNSVISSECTGFALHITSTKARPSVVHLVYTTRQDLLHIIPLGSSNFTSSPPEVLDVGSGKRQPAPKDFNIQRVWERGARIVSTLGGSDVAVIMQPSRGNLETIYPRGLILHAVEAALAEQDFAEAITCARRHRIDLNVIVDFLGEKEFSRLAPDFVKQVGKLSLVTELVSCLGNENVLETTYKKTLSTLNPEDRMVPAVSSNKMQVVLEALRSAVENHVTDSPSREMCLLTILARNDPPLLEEALKRIKLLREGELGLGTSDDEEALEAIESQGKLVAESALKHLIWLADADAVFDAALGLYDLHLAAMVASHSQRDPKEFLPFLQELEDMPPSIMCYKIDCKLKRYASALRHLSSAGETYFNEALDHVQSHPELFSLALSIFTGESQRSSIMEAWGEYFLSQERFEDAAITFRSCSQLHKALAAYRAGGHWQGVLMVAGQLSMTPDEITNLALELREELQAMGQPKEAARVALDYCKDVKDAVGLLIEARDWMEVLRLCYLHAQPDIVDTIVQPAAVECANGLVGQFQEGVEKVGKYCARFVAVHQRRVLLEAKIKSDQGEDRFDDDTASEASSNLSGMSVYTRGTARTAATGRTRARRQGKVRAGSPGEELALVEHLKNMAISPQLADELRPLLQILVFVKREDLSCKLQQAASKFQATQAEAMRAVEENGITVDKTAANRVVNWSYQALERVL
The following text describes a protein:
Function:
This protein binds preferentially and cooperatively to ss-DNA. Involved in mitochondrial DNA replication (By similarity).
Subcellular Localization:
Mitochondrion.
Sequence:
MLFLKSSRAFSKRLFSSSTVRYRDIQRLTLTGNLTKDVERLQSQKGNEYMRYTVASNNGKDVAPTFHSVYVFDSYNFDRLQTILRKGTRVYVEADAVWRSVPAGNEGSQAKMSLRHVSADVLFYPRNKNGDESGEETHPELDADPMINSF
The following text describes a protein:
Function:
Involved in the biosynthesis of the enzyme cofactor mycofactocin (MFT). Acts as a glycosyltransferase that catalyzes the oligoglycosylation of pre-mycofactocin (PMFT), adding up to nine beta-1,4-linked glucose residues.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MTATRLPDGFAVQVDRRVRVLGDGSALLGGSPTRLLRLAPAARGLLCDGRLKVRDEVSAELARILLDATVAHPRPPSGPSHRDVTVVIPVRNNASGLRRLVTSLRGLRVIVVDDGSACPVESDDFVGAHCDIEVLHHPHSKGPAAARNTGLAACTTDFVAFLDSDVTPRRGWLESLLGHFCDPTVALVAPRIVSLVEGENPVARYEALHSSLDLGQREAPVLPHSTVSYVPSAAIVCRSSAIRDVGGFDETMHSGEDVDLCWRLIEAGARLRYEPIALVAHDHRTQLRDWIARKAFYGGSAAPLAVRHPDKTAPLVISGGALMAWILMSIGTGLGRLASLVIAVLTGRRIARAMRCAETSFLDVLAVATRGLWAAALQLASAICRHYWPLALLAAILSRRCRRVVLIAAVVDGVVDWLRRREGADDDAEPIGPLTYLVLKRVDDLAYGAGLWYGVVRERNIGALKPQIRT
The following text describes a protein:
Function:
Catalyzes the ATP-dependent phosphorylation of 5-deoxyribose into 5-deoxy-alpha-D-ribose 1-phosphate, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites. Is also able to catalyze the phosphorylation of 5-methylthioribose into methylthioribose 1-phosphate, but this enzyme may not function in methionine salvage in B.thuringiensis since it exists a paralog (MtnK) present in the methionine salvage pathway cluster. Does not act on 5-deoxyribulose, 2-deoxyribose, ribose, fucose, fructose, fructose 6-phosphate, and glucose.
Sequence:
MSKFTKYFLMEASDVIAYVKEKLSKFEHAKGLKCKEIGDGNLNYVFRVWDKKENMSVIVKQAGDTARISDEFKLSTNRIRIESDVLQLENELAPGLVPKVYLFDSVMNCCVMEDLSNHTILRTALINHQIFPQLADDLTTFMVNTLLLTSDVVMNHKEKKELVKNYINPELCEITEDLVYSEPFTNHNKRNELFPLNEGWIREHIYSDKELRMEVAKRKFSFMTNAQALLHGDLHTGSVFVRDDSTKVIDPEFAFYGPMGYDVGNVMANLMFAWVNADATMPPGAEKDTYMDWLQTTMVEVIDLFKKKFLDAWDIHVTEIMAKEEGFNEVYLQSVLEDTAAVTGLELIRRIVGLAKVKDITCIENEEARARAEQICLKVAKSFILRANQYRTGRSFVETLKEQSMHYAE
The following text describes a protein:
Function:
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide.
Subcellular Localization:
Cell membrane. Note=As unassembled monomer may localize to the endoplasmic reticulum.
Sequence:
MGKFKLGNWAAMIGMAACWCLIAGGIMGIWYERRYIAIYSICVGGVLYPLLYPLSFLGPLKAIFHQYYVAAALMAGLSVLCYFLVPTMLAAMVMDISAVVFLISAIKGERGDFFDKQD
The following text describes a protein:
Function:
As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
Subcellular Localization:
Nucleus.
Sequence:
MTFELSTGFFDAVENATSRDELPEKFRAPILQIVRPMSELPGKNRFKVTLFDGEKPGMVFGDLDNLPQERPGKFDIVKLSNFELVMAKQRGVVYVHQMDFLSHADAALGLDTEEDAELPGGAAATAPAAATSNPTPAKRMASTNEIPAGVQAQGFPATVMPIERLSPYQNKWAIKVRVTSKADKKKFSNTKGEGQLFNVTFIDETGEIRATGFNQEVDKFYPMLEEGQVYYVTQCRVSMANKKFSNVNNDYELVFGRDTVIIQADEAEAAAIPTANYSFVTLDKLQDVEVGNNVDVLGVVQNVGPLEDGVAKATGNPYKRRNLMLGDKSGFATRLTFFGEKATSFDEGTVPVGTIIAIKGARVGDFNGRNLSTSHSSTIAVEPAIDETYALKGWYASEGKQTSFKQLQTTTTNKPVAATPIDVATSSYGQSEKPDYYTLQAWVVHVRTGNFAYPACQTPDCNKKVVEHGDEWRCEKCEKNMDKPLYRYILSINVGDATGSMWLTAFNEPAEVIMGMTADQLTEIQTSQGDDEFEQAVQKVTGKQYTLRCRSKQEFYNEESKARHQVLTAQALDYLKDIDELIKDLDQYM
The following text describes a protein:
Function:
Unidirectional NADP(+)-dependent cortisol dehydrogenase (in vitro).
Subcellular Localization:
Secreted.
Sequence:
MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGHD
The following text describes a protein:
Function:
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.
Sequence:
MNLRQLEILRAVIRHRTTVAAADELALSQPAVSNALKTMEAQAGFALFERVNNRLFPTAEAMALYKESEAIFALHAKLENRVRDLRENRSGHLAIVATPPLAYSIIPSALSGFLRRRPETRVFFDVRRYEGIIEGVLSRVAELGFALGLTHHPGIAHEVVHTGEMVCVLPPQHPLADRPVISAADLSGLPFIGLERGTRLGEAVRDSFARAGAPFRPTVEVRYCNTACVLAAAGVGAAVVDPFSPRQNGGNGLVVRPFTPTTHAVAYMLWSEAEPLSRLAKAFLSEVRKQSALLEGPAPHQQHGAESD
The following text describes a protein:
Function:
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.
Sequence:
MPETALGSFPDVGASYYLSRLPGFFGEYVGLMGARLDGAEMLACGLATHFVPLEKLSSLDDALCKATTGDPKIINNIILHDFSNKNPTLKEKSHYFRLKTINSCFSRRTVEEIISALEEGDKKMDDWISWTIQALKKASATSLKISLRSVSTYTALRAGVYLESDILPHREIDAVDPKSRHKGNLETEILLESKGVNYTSIRPVYIYGPGPLNYNPVEEWIFHRLKAGRPIPIPKSAGGFPEPDIIHYNPKEFHYGKKKAFPFQDQDFPMIGVMGGAIPMGTFCYGRSCTV
The following text describes a protein:
Function:
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MTEKKSEDYFAVAPPKRSGWASFKIFLWNGETSEFLGRSASSWAKIFLFYVVLYAFLAAFFAAMLMVFFQTLDLYQPRWQNANGLIGTNPGLGFRPMPTSSNVESTLIHFKHGTAGNWKHWTSELEKFLYPYDTVASSGEYFTSCSFDKWPADGKVCNFDIKLLGTQCTKEENFGYERGRPCIVLKLNRIFGWIPEPYDDLNDLPANMPTELKEYIKTKATENKEQLKMIWVSCDGENSADREHIGNVTYTPFRGFPAYYFPYKNVPGYLSPIVALQFQKPEAGVLINIECKVWAKNIVHDRQRRLGSVHFELLMD
The following text describes a protein:
Function:
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used during anaerobic growth, and succinate dehydrogenase is used during aerobic growth. The QFR enzyme complex binds 2 quinones in or near the membrane; 1 near the [3Fe-4S] cluster (QP is proximal to the [3Fe-4S] cluster, on the cytoplasmic side of the membrane) while QD (the distal cluster) is on the other side of the membrane. It is not clear if both of the quinol-binding sites are functionally relevant.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG
The following text describes a protein:
Function:
May play a role in retinal photoreceptors development.
Subcellular Localization:
Cytoplasm.
Sequence:
MIQSDKGADPPDKKDMKLSTATNPQNGLSQILRLVLQELSLFYSRDVNGVCLLYDLLHSPWLQALLKIYDCLQEFKEKKLLPATPHAQALSYEVVELLRETPTSPEIQELRQMLQAPHFKALLSAHDTIAQKDFEPLLPPLPDNIPESEEAMRIVCLVKNQQPLGATIKRHEITGDILVARVIHGGLAERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILAMSRGTIMFKVVPVSDPPVNSQKMVYVRAMTEYWPQEDPDIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDPATCAGLVPSNHLLKRKQREFWWSQPYQPHTCLKSTLSISMEEEDDMKIDEKCVEADEETFESEELSEDKEEFVGYGQKFFIAGFRRSMRLCRRKSHLSPLHASVCCTGSCYSAVGAPYEEVVRYQRRPSDKYRLIVLMGPSGVGVNELRRQLIEFNPSHFQSAVPHTTRTKKSYEMNGREYHYVSKETFESLIYSHRMLEYGEYKGHLYGTSVDAVQTVLDERKICVMDLEPQDIQVVRTHELKPYVIFIKPSNMRCMKQSRKNAKIITDYFVDMKFKDEDLQEMENLAQRMETQFGQFFDHVIVNDSLHDACAQLLSAIQKAQEEPQWVPATWISSDTES
The following text describes a protein:
Function:
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.
Sequence:
MLREFVRCSFPLAYFDTLWQGNMLVLLVLGWMELKCLLVVLQPTLYHRIHQESKFDSHRQQLSKTSPTKILNGTPNHQNNNTGKGKKKKVQWIAQQNTLQPSSSNRQAKAPSQYNLERSKHPPEVIIYAESEVLDKKDDWISSTIQSLKKAPPTSLKISLRSHPFYCITRLTLLLQGCRAILIDRDRNPKISRFIHSCAYLFIYIQWEPSRLEIIRDDDVDHYFSKIDDEDWEDLKLPPRSNMSPYAIVKL
The following text describes a protein:
Function:
AGC kinase which plays a role in TOR complex 1 (TORC1) signaling pathway which mediates temporal control of cell growth in response to nutrients. Required for phosphorylation of ribosomal protein S6 (rps601/rps602) at 'Ser-235' and 'Ser-236'.
Subcellular Localization:
Cytoplasm.
Sequence:
MPVFMFDEHDNLNENYNSHLSSDDEIAEEGYDFEELEASASTITSSSDLKDGKNAKDEKGTVEFKVAAHGDFISSKGDNYVPSGKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADCRSFVGTEEYCAPEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPFYVTSDARDIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPCITNPEAAENFSVEFTKLPLSTTPILHEEFGNLTIGSHSSAFQGFTYVASPNFLNCEFLSNNAVSNH
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
LFAQPLNSQTISKKKKRNDKMSKKKETVKEIFASCCFSSLGLDSTLCDQLRERLGFEAPTKVQAQAIPVILSGRDVLVNAATGTGKTVAYLAPIINHLQSYSPRIDRSSGTFALVLVPTSELCLLVYEILQKLLHRFRWIVPGYVMGGGNRSKEKARLRKGISILVATPGHLLDHLKHTSSFLHTNLRWIIFDEADRILELGFGKEIEEILDILGSRNIASIGEGNEVSNVKRQNLLLSATLNEKVNHLTKISLETPVLIGLDEKKFPEDKSNVHFGSLESDVKEEVEHPNTTLSSSTEDFMLPAKLVQRYVKGIS
The following text describes a protein:
Function:
Essential protein involved in pre-mRNA cis- and trans-splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNA substrate.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Found predominantly in the nucleus.
Sequence:
MLTTAKANPLEALRSAKENKELSGQLEHHRSLRAIKLKVLLYREEREAAGVPPDVISRECATLHGSLLRNYMEEAQEARRLGAAELAQKTAERFASAFQVRPGSLGDAFDRRHREVERQAAEGARKEAIERRIVERVKRIKGE
The following text describes a protein:
Function:
Starch-debranching enzyme involved in amylopectin biosynthesis in endosperm. Functions by removing excess branches or improper branches that interfere with the formation of double helices of the cluster chains of amylopectin and crystallization of starch. Works together with ISA1 as heterooligomer. The heterooligomer ISA1 and ISA2 possesses higher affinity than the ISA1 homooligomer for various branched polyglucans in vitro, but no marked differences exist in chain preferences for debranching of amylopectin and phytoglycogen between these forms.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MASLPAPPTPLGSCPRGRGGGRVVARPRRAGLACAARSCYRFRTDDDGVVDVAVSGEDGDGGGGGYAVSVEVPGTRGREGGLVLRASGSGEGVPLAPAAGGASLAAELSFDPTRAPFYLSFLLTDASGAEIRTHRKTSFRVPVGVGPGSPAPLGMSISGDGAVNFAVYSKNANAVSLYLYAAAVGGGGGDEPALEIDLDPYIHRTGNVWHVSLASVDGYVSYAFCCGGIRRPLLDPYAKVIGDFVSSNSVYDEGVTAPSMRCFASLAIAPSYNWGRDRHPRLPLEKLVVYRANVALFTKDRSSGLPDDAAGTFTGLSAKVEHFRSLGVNAILLEPVFPFHQVKGPYFPYHFFSPMNLYSSKGLSVSAIKSMKDMVRVMHRNGIEVLLEVVFTHTAEGESECQTISMRGIDNSSYYIANGIAGCKASILNCNHPVTQKLILDSLRHWVLDFHVDGFCFINAPFLVRGPGGEYLSRPPLLEAITFDPVLSMTKIIADPWSPLDISNVQFPFPHWKRWAEVNTRFSIDVRKFLKREALISDLATRLCGSGDLFSTRGPAFSFNHVSRNSGLSLVDLVSFSNDDLLSESSWNCGEEGPSENSAVLQTRLRQIRNFLFILFVSLGVPVLNMGDECGHSAAGSVSYKDRGPLNWRGMKTTFVKEVTGFISFLTALRSRRGDIFQRREFLKLENIHWYGSDLCEPGWDDPTSNFLCMHINAEVDEMAADSVRGDLYICFNANEESVSAALPALAEGSVWLRLVDTSLAFPGFFATESNPKVQQVPGLSSYHVEAHTCVLFESKSALA
The following text describes a protein:
Function:
Involved in nonsense-mediated decay of mRNAs containing premature stop codons.
Miscellaneous:
MISCELLANEOUS: Present with 6090 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MTQYNFIIDASAFEKGLGNIKRWCSDCTEAVTLNFYIPTFTLNELDFLQQRRKSFAARESLKFIDRLDDSKFANLKVFIEFPEVLDIILWSDVMEHNDSSGKINIAKLPKRLKNLLKSCIYKCYLEGNEGLHWFLISEDPQIREMAMQCNIPSCSIVDVDSILSKDMNDKSFRESEKFNNMMLKNGTKEESENGREIIRTNFNKTVYASRGTGELWSP
The following text describes a protein:
Function:
Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.
Sequence:
MGVKKKREMQFAALTVCHQDLETLRSFADVEGKNLASLLLHCVQLTDGVSQIHSVKQIVPLLEKVDKNGVCDPIIQRCLDILASIYFSLTLKNPLKKVLASSLNGLPECFLNEAAHSFTFHLQEELDTADLHSYRKVMDNISSCMENFNLGRASVVNLLQNVLHFLQKSLIEVQEENRKFAGNHIVQTQLMNDLLVGVRVAMTLVQKVQGPQSNLWNDSSSPIWQSMCGLLSIFTRFLNDDDLLQTIQSTSGLAVILFIKTMFRPSEKLPGLISSLLLQSADCTSIPDWLMSSCRSLCCADVPASALLFLCQGTLAMLDWQDGSMGPSREALLLDTVHVLFTLSSQIKESTLEMFLSRILASWTNSAIQILESSSPSLKDHLNGDSSIPRRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHRLTIEGADLVTDPFFLELTKSLLQLEWHIKGKYACLGYLVESLGIEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKSQTVTNTWMDKWHETWVFPVLSVLCGGNLDQRSYVIDYYLPRLLNYSPESLHYMVQILQTPIDTETGSCNHRGALGALMACLRTARAHGHLQSATHAWENLVCSARVKQGLIHQHCQVRIDTLGLLCESSRSTEVVSREEMQWVQFFLTYNLNSQSPGVRQQICSLLTKLFCRIQESSQVLYKLEQRNSTPDSEKRSTREQPSVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSIAEVFPASKGNIQTVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMNLSSVTAGQLQGSEKLQDLFQAALELSTSTKPYDCVTASYLLNLLIWQDALPASLSASSAQQPTCGAGEKSAVVERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQKLPLHDLRLVSEWKPVLGKLLLLSYRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQVILNEIQPRDTNDYFSQAKILKECDSFDLEDLSTSVSNIDSSAEIKGKEEKACDVTAQMVLTCCWRSMKEVALLLGTLCQLLPLQPVPESAAGLLTVQQVKEIGEYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLWSVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEPKKGRMDLLRVTMRELISLALSADDSKGRVPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILGFTSPVWAVRNSSTLLFSSLITRVFGVKRGKDELSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDLGDPDGHPGMFLLLLVLERLYPSPMDGTASTLSLAPFVPFIIRCGRSPFYRSREMAARALVPFITIDQIPSTLHALLDSLPSSTDQCFRQNHIHGTLLQVFHLLQAYITDSKHRINADFLQELSDITVCTKAKLWLAMRQNPCLVTRAVYIDILFLLTHCLDRPEEGKHTALESLDFWEDVRRIILGSELITGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQATAVPLSFSQLLKSSFPEVRLLALDALLERAASSEQGQKGPPPLLYSMGEEFLLLAMKEDHPGCFCRVLKILYHLNPSEWLPQTECSVHLSPKEFLVWTMDIASNDRSEIQGVSLRLASKIIAYLVQSCEKNKDSVALELRRWVQLIVWSCGDHLPTASRLAVAEVLSGTAPLFLTSPQPILDLQDTLSLWRCVLTLLQSEEQPVREAATETVTTAMSQGNTCQSTEFAFCQVDASIALTLAFAVLCDLLQQWDQLGPGLPILLGWLLEEGGDLKDLMQSPHQGEEEHIFEKSEVNFWAETLTFVKYLCNQVFHLLCQSGCQSSHSQLSHLQRTASEQHRLISQLFRELPLSAEFLKTVEYTRLRIQEERTLAVLRLLACLEGKEVLRAEDCPREWRQEMAPRTEAAC
The following text describes a protein:
Function:
Participates in exocrine secretion.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MASTAVGLGGGEGDPGAGGPPAGSAHPDDASSMSDDVFEDAETTQARIEELRRRPFGDGSYNPPAAPASVSASITTTTTQQQQQHHNPSHHHQSSHHQPSHHHHHHHHSQLSLTGSHHYHDDAIMAPVQRSATGYPGYRPSREAMQMYAYGTDDYDDDYNDGWRSYRYDEVDMHPAPSNAHQQPFDDTVNHKTILLGDSGVGKTSFLVKYNTGEFRLGSFSATVGIALTNKVVVVDGTRVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKTTYDNIRAWLGEIREYAQEDVVIVLIGNKADCSGSERQVKREDGERLGREHNVPFMETSAKTGLNVELSFTAVARQLKSRGYEHGDDGKFNVHDFVRDNTKARSVCAQCRNM
The following text describes a protein:
Function:
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for the translocation of the substrate across the membrane. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFIIKSMLYRLMQMIVVLFVISTLTFILMKLSPGNPVDKILHLDVAQVSTEQINATKDKLGLNDSLLVQWWHWMNHLLHFNLGKSFESKEPVTQILFNYAPITLLISFSTLVVSLCISIPLGIIAAKRFHKWTDKVIRVISTLSISLPAFFIGIILLFIVTNLMNIDSVILSQFILPVITLSLGMCAYIIRLVRSNLLMLLQSNIVQASRLRGMNERYILIHDLLKPTILPIIPLLGISLGSLIGGTVVIENLFDIPGIGYLLMDSIKSRDYPVIQGCVLFIGFFVVIINTIADLLTLLLDPKQRLQLGNPKIKTNTPLISESSDRHA
The following text describes a protein:
Function:
Inhibitor of HGFAC. Inhibits serine protease activity of ST14/matriptase in vitro. Inhibits serine protease activity of TMPRSS13, via the BPTI/Kunitz inhibitor 1 domain.
Subcellular Localization:
Cell membrane. Cytoplasm. Secreted.
Sequence:
MAARRLAQASISTVCVWLLCALGLQGTETELPSAPPEFSGGAACLNRFTSGVPAFVLDTEASVSNGATFLGSPTVHRGWDCVRACCTTQNCNLALVELQPDGGEDAISACFLMNCLYEQNFVCKFAPKDGFINYLTQDLYNSYRELRTRGFGGSRIPRIWMGIDLKVQLQKPLVLRDADNTDWHLLQGDQDVSVKRNHPEEVELWGLKEGTYLFQLTRTDSDQLEETVNLTITVLTAEQTEDYCLASYKVGRCRGSFPRWYYDPKEQICKSFTFGGCLGNKNNYLREEECMLACKDVKGISPKRHHPVCTGSCHSTQFQCSNGCCIDGFLECDDTPDCPDGSDEATCEKYSSGFDELQSIHFLSDKGYCAELPDTGFCKENIPRWYYNPFSERCARFTYGGCYGNKNNFEKEQQCLESCRGISKKDVFGLRRESSVPSAGSVEVAIAVLLAVCIIVVLTILGYCFFKNQKKNFHSPLHQPPPTPASSTVSTTEDTEHLVYNHTTQPL