lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions.
Sequence:
MAAAQAMAKMSVGSPACNRAAGSLCRWRGAVAVRLGGSWSWRKSPFLGGRMAVGPRRSRPVSRNPVASPVQMNLSFGKTMKWWEKGLQPNMRAIHTAQELVDSLINAGDGLVIVDFFSPGCAGCHALHPKICQFAERNPDVQFLQVNFEEHKSMCHSLHVHVFPFFRFYRGAQGRLCSFSCTNATIKKFKDALAKHKPDRCSLGPIKGLEESELLALAANRDLQFTYTKEQDLAPSMEDGAEVITHDHPRLPAAAKPLVRQGSEDRAVVSSGR
The following text describes a protein:
Function:
High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MDMFPLTWIFLALYFSGHEVRGQADQPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSVLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPDKYPHNLDCTFTILAKPKMEIILQFLTFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSATGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSMYSDGRWTPQQSRLHGDDNGWTPNLDSSKEYLQVDLRFLTVLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHSPLLTRFVRVRPQTWHTGIALRLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTREYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGAPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEHIQDPRTQQPKLFEGNMHYDTPDIRRFDPVLAQYVRVYPERWSPAGIGMRLEVLGCDWTDSKPTVETLGPTVKSEETTTPYPTDEEATDCGENCSFEDDKDLQLPSGFNCNFDFPEEPCGWMYDHAKWLRSTWASSSSPDDRTFPDDRNFLRLQSDGRREGQYARLISPPVHLPRSPVCMEFQYQATGGRGVALQVVREASQESKLLWVIREDQGGEWKHGRIILPSYDMEYQIVFEGVIGKGRAGEIAIDDIRISTDVPLENCMEPISAFAGENFQVDIPEIHGREGYEDEIDDDYEVDWSNSSSPTSGSGAPLADKEKSWLYTLDPILITIIAMSSLGVLLGATCAGLLLYCTCSYSGLSSRSCTTLENYNFELYDGLKHKVKMNHQKCCSEA
The following text describes a protein:
Function:
This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
Sequence:
METIAKHRHARSSAQKVRLVADLIRGKKVSQALETLTYTNKKAAGLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
The following text describes a protein:
Function:
Acts as a negative regulator of salt tolerance. Mediates sugar response during early seedling development.
Subcellular Localization:
Nucleus. Note=Colocalizes with UGT72E1 in the nucleus.
Sequence:
MKVKEETLKNLGDGVVLRPVDHCSSIWSMKMNMKNFLKKLHISPNQSDEAEGSISTTKSNHHKSIDVSSSSSPRSHHSNSPEIKPFSGLSNWLSSVGHRKIPSPPNSFNAKNRAATVDDTVVVNGSEHVDLGSKDPAVEEENQIQLALELSAREDPEATQIEAIKQFSLGSCAPENSPAELIAYRYWNYNCLGYDDKILDGFYDLYGVLNASSAERIPPLLDLQGTPVSDGVTWEAVLVNRSGDSNLLRLEQMALDIAAKSRSVSSSGFVNSELVRKLAILVGDYMGGPVVHPESMLRAWRSLSYSLKATLGSMVLPLGSLTIGLARHRALLFKVLCDSVGVPCRIVKGQQYTGSEDVAMNFIKADDGREYIVDLMGDPGTLIPADAAGLQIDYDESAYSASPGDNDSIHVASSSNGIESSYEENTEFRTGEHRSSTKSSGERNQSGGGGDLIVHPNISREDVKNQKKVEKAPFQNLSSRPIHSFTHMRSPSWTEGVSSPAAQRMKVKDVSQYMIDAAKENPRLAQKLHDVLLESGVVAPPNLFSEVYPQQLEATVESKNSTEAKKERGKDLETTQEGRHQNGFGPVRFLPPLPRVQSKTNAHDQRDNGKVVSQSDSSHSEASSTEYARTVPAAVAAAAVVASSMVAAAAAKSANSDSSPIELPAAAAATATAAAVVATAAAVSRQLELGSNSDGDDGSGGHEPQGSGDSNHGPNSGGERISDKSIGNESSKSDCDDVSDCEILWEEITVGERIGLGSYGEVYRGDWHGTEVAVKKFLDQDLTGEALEEFRSEVRIMKKLRHPNIVLFMGAVTRPPNLSIVTEFLPRGSLYRLIHRPNNQLDERRRLRMALDAARGMNYLHSCNPMIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTYLSSKSTAGTAEWMAPEVLRNEPADEKCDVYSYGVILWELFTLQQPWGKMNPMQVVGAVGFQHRRLDIPDFVDPAIADLISKCWQTDSKLRPSFAEIMASLKRLQKPVTGSNIPRPVPSSSSLPTEHEQKD
The following text describes a protein:
Function:
Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
Subcellular Localization:
Cytoplasm.
Sequence:
MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLRDFQWDSDHIYLIMEFCAGGDLSRFIHTRRLLPEKVARVFMQQLASALQFLHEQNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSVGVILYEALFGQPPFASRSFTELEEKIRSNRVIELPLRPPLSRDCRDLLQRLLERDPNRRISFQDFFAHPWVDLEHMPSGESLARATALVVQAVKKDQDGDAAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNQALLRQGTSAQDLLRDGPGQTSAPRGPGSGFGCHGQGGGGWWGAGCPGPVPACPGGVAGAAGSGAHRPEAGAASHRGSEPHGSSRIPEGAGQDEGVSLGSRDPGQGGTVRVRSYLVHPAVTPEG
The following text describes a protein:
Function:
Regulates expression of the homeotic selector genes by influencing higher-order chromatin structure through interaction with other proteins.
Subcellular Localization:
Nucleus.
Sequence:
MHLQNTHNTMESNAAMDAASPASRDVRQFHDLITCRLCRGYMIDPTTVDYCYHTYCRSCILKHLLRAVYCPECKASGGKEINELNLKSDDTLRSLIYKLVPGLYQRECKELADFKEQHDLVDEQTTDEPEFFTTTELISLSLEYHPAMLHQCGPGEVPPTIYLQCAAGLPVELLKRFLCSKYNIETDNGLVEVEVTYKDEVLPTNFTLMDVAYCYNWSRESPMAFCYRILLYDNEQTKNDENNLSRINQDIEPEHSVRRSKSAKSVTFAEDLESEIDSGSPRSKVRCKTPPKVSPSSKNKRLTSSKREAEPESPVSNFKSLRSNDMRYSDYAVSKVKSEPEQEQFLLPREREQQPLEANTNIVVSIPPSQLRKSYVDAEDFELKTANRKGVGHLPKLKIELNSMKSKLSMPLSAGPRLEDTSCSLSCSAQQLDLETYAKNIGLKPIEQPLQQSASNPDSKYSPNASPMSSCSSSTNGSSSSLGTADASTSTSTSSSHRKRKKKHSKEPKDANGKRKKLHAEISSQTDGKMKVKITAKPNHKLDFKRSHSLASGELDLQKLKLDSTSTSEALNRTLGEEARSINSLVVGGAPTPPPTPTAEPEQQQQQQQQQQQPQQQQQQQQQQQQQQQFVVLPKIKDLTLPTSPPLPPSLFKAYTPSTTPTAPHTVAGGKPKQQQQQMPQQPQAVLQQSLAKTNPAKPPLSSNNNRKPNSGHFAVPQAPTHRNMYHMQRYQSTPSSIASAANKMPKRSMSLDESHPAKQARLSQAQAMASSYAAKLHMQTSNQAKSQAAAFLPNPQMRSYGLPDLGSKPTLPMLCPASSSSQVTITPRPRATPSIYSFSEPNIHVPALEIVRLPVNKQSAGGKGLTMPPLSPPATSSARLMGPPAALPKHAGHGHGAAKRSCQMPTMPMPLPLPLPMPMTTIPAIVKSPPLSVALSGQRNNKGNSSNSNAYRTSPPALINLRNTAAPQHSFPSKSSPKVEANSKKSPPAAGCQGKTNGTAALDKSKTSLREFRPAVQSAVTATATTSVTTAAGAGAGAGTGTGTALAKDADILDLSANPGRSNNDAKLAPNSPPAGNNNNNNNNNNNNNNNNNNNNNNSTSNSLEAALNKIKQNISANSNGGPSTTSGSNSNGTTNGDDLQNLHMLSESATAREKISIKAASSGNGSGSTSSSSAKPKNANALVRPQNASVRSIPNPSALAFRNQPAAASTAASISKPLTVRAEEKPKVSTSNPGSLSPTNTSSSSSSSSSGSSGCSAATSPRAMTKKPTTIDQVAANLNIRAEAKAAALAEEAPPVLSSNAAKSPELAKTTTAVALRPEPKETPITVSAASTLLTIPSAVSSVSAVPETMAKPPVQIANAPVASSA
The following text describes a protein:
Function:
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Subcellular Localization:
Mitochondrion.
Sequence:
MLRTIRPARTTLVRAVRPVRPVSGRVGRLGRHVTTGTTSSTTSASSPDLSTTLAMAIEQQGPMSVATFMKHCLTNPSGGYYIDKDPLGAKGDFTTSPEISQMFGELVGLWLAAQWLYYGQKQPFRVIEYGPGRGTLMDDSLRALVSAKSTGAKEALKEVLLVEASPVLRDAQRKKLCGAESQFKTEEDGSITCVTKYGVPIRWYEDSKMLDKLASSNDPLHNYIVAHEFFDALPIYQFEKTDKGWRELMVNYGVENKTKESSILLPGQTHIKSSDLDKDKKKTFHLVTAPTWTVASKVIPQSHKRYRDLPEWSKIEVCPDAWDVANQMGRLVAKGGAAFIVDYAVKPGVPVNTLRGIRDHKICSPFEEPGKVDLSADVDFTAIGIASRSKNKENVSAFGPINQATWLKNMGIEMRTEKLMEGKEEYIKKRIESQYKRLVDIGINGMGKIYKAFFLTHSSHGYPVGFPIPEPKDLKEPHQKPEKDPKDTEPKVVEV
The following text describes a protein:
Function:
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MDFIVIDGSYLEGGGQIIRTAVSLSALTQKPVKIINIRKKRKNKGLAPQHVSAVKAVKKLCNAEVFGLNVGSEELTFIPSKLSPKDFTIDIGTAGSISLVIQTLLPLSLGINKKFTVKIKGGTDVKRAPPIDYVKNVTLKILRNFGVLTELKVLKRGFYPEGGGEVIFEVKPSKIKKFDLIEHSKSNLVEGISYVQNLDESIARRMRKKAVDLLNKEKLLPNIKIECSKGISTGAGIVLWNDTLGGSCLGEKGLRAEIVAERAVNELLKERESGMALDKYMGDQIIPFLAFGKGIVGVSEITNHTKTNMWVVKHFLDVDFEIKEYKENNCNGFTIEVV
The following text describes a protein:
Function:
Transcription factor involved in chondrocytes differentiation and cartilage formation (By similarity). Specifically binds the 5'-AACAAT-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes, such as COL2A1 and AGC1 (By similarity). Required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes: SOX5 and SOX6 cooperatively bind with SOX9 on active enhancers and super-enhancers associated with cartilage-specific genes, and thereby potentiate SOX9's ability to transactivate. Not involved in precartilaginous condensation, the first step in chondrogenesis, during which skeletal progenitors differentiate into prechondrocytes (By similarity). Together with SOX6, required to form and maintain a pool of highly proliferating chondroblasts between epiphyses and metaphyses, to form columnar chondroblasts, delay chondrocyte prehypertrophy but promote hypertrophy, and to delay terminal differentiation of chondrocytes on contact with ossification fronts (By similarity). Binds to the proximal promoter region of the myelin protein MPZ gene (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MLTDPDLPQEFERMSSKRPASPYGETDGEVAMVTSRQKVEEEESERLPAFHLPLHVSFPNKPHSEEFQPVSLLTQEACGPRTPAAQHSTMEVDGNKVMSSLAPYNSSTSPQKAEEGGRQSGESVSSAALGTPERRKGSLADVVDTLKQRKMEELIKNEPEDTPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQFYAAQLAAMQVSPGGKLLGLPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPASPTSPHMPALRINSGAGPLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQALDGKVAVVNSIGISNCRTEKEKTTLESLTQQLAVKQNEEGKFSHGMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYEEYEEEEEDPDVDYGSDSENHIAGQAN
The following text describes a protein:
Function:
Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.
Sequence:
MERVALYILTMDAINFCFWPVSEAKDATNSVKNGLEYEHLAIGLRKLAELDDGNSQVNVKTSESGVYELPDMQIRCQLLNELGKGLLEQHGGSALQMISKANQSADALVRIIMDTFPGFRDYVDTDASGEWETVKASLTAIHLHKRAQIATADIWAALGRCNDQSVQTTNTTNPEHAKLFTCCHFTDMDAVTTFPDYRVPQILRHVAVLRYGSQLANLIDNQLELEKSGMDEVSIRASTVVAVEELLSDDVSAVTIDWYLWQKGERLDRANQLEPHHRVRTTFY
The following text describes a protein:
Function:
Binds to actin, and functionally associates with actin structures involved in the development and maintenance of cell polarity.
Miscellaneous:
MISCELLANEOUS: Present with 3510 molecules/cell in log phase SD medium.
Sequence:
MNIVKLQRKFPILTQEDLFSTIEKFRAIDLDDKGWVEKQQALEAVSKDGDATYDEARETLKHVGVDASGRVELDDYVGLVAKLRESKTGAAPQTTFNVAPNSTPIVSTAATGLQHKGKGTQAKIIVAGSQTGTTHTINEEERREFTKHINSVLAGDQDIGDLLPFPTDTFQLFDECRDGLVLSKLINDSVPDTIDTRVLNWPKKGKELNNFQASENANIVINSAKAIGCVVVNVHSEDIIEGREHLILGLIWQIIRRGLLSKIDIKLHPELYRLLEDDETLEQFLRLPPEQILLRWFNYHLKQANWNRRVTNFSKDVSDGENYTILLNQLDPALCSKAPLQTTDLMERAEQVLQNAEKLDCRKYLTPSSLVAGNPKLNLAFVAHLFNTHPGLEPIQEEEKPEIEEFDAEGEREARVFTLWLNSLDVDPPVISLFDDLKDGLILLQAYEKVMPGAVDFKHVNKRPASGAEISRFKALENTNYAVDLGRAKGFSLVGIEGSDIVDGNKLLTLGLVWQLMRRNISITMKTLSSSGRDMSDSQILKWAQDQVTKGGKNSTIRSFKDQALSNAHFLLDVLNGIAPGYVDYDLVTPGNTEEERYANARLAISIARKLGALIWLVPEDINEVRARLIITFIASLMTLNK
The following text describes a protein:
Function:
One of the extrinsic, lumenal subunits of photosystem II (PSII), which stabilize and protect the oxygen-evolving complex. PSII is a light-driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating a proton gradient subsequently used for ATP formation. Required for dimerization of PSII and for binding of PsbQ to PSII.
Subcellular Localization:
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=CyanoQ (PsbQ) binds to the large lumenal domain of PsbC (CP43) between PsbO and PsbV.
Sequence:
MRFRPSIVALLSVCFGLLTFLYSGSAFAVDKSQLTYDDIVNTGLANVCPEISSFTRGTIEVEPNTKYFVSDFCMEPQEYFVKEEPVNKRQKAEYVKGKVLTRQTTSLEQIRGSIAVGADGTLTFKEKDGIDFQPITVLLPGGEEVPFFFTVKNFTGTTEPGFTSINSSTDFVGDFNVPSYRGAGFLDPKARGLYTGYDNAVALPSAADKFRTNKKETPLGKGTLSLQVTQVDGSTGEIAGIFESEQPSDTDLGAKEPLDVKVRGIFYGRVDTDV
The following text describes a protein:
Function:
Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication.
Miscellaneous:
MISCELLANEOUS: Present with 6080 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MATYQPYNEYSSVTGGGFENSESRPGSGESETNTRVNTLTPVTIKQILESKQDIQDGPFVSHNQELHHVCFVGVVRNITDHTANIFLTIEDGTGQIEVRKWSEDANDLAAGNDDSSGKGYGSQVAQQFEIGGYVKVFGALKEFGGKKNIQYAVIKPIDSFNEVLTHHLEVIKCHSIASGMMKQPLESASNNNGQSLFVKDDNDTSSGSSPLQRILEFCKKQCEGKDANSFAVPIPLISQSLNLDETTVRNCCTTLTDQGFIYPTFDDNNFFAL
The following text describes a protein:
Function:
The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.
Subcellular Localization:
Secreted. Host cell membrane.
Sequence:
MIKLKFGVFFTVLLSSAYAHGTPQNITDLCAEYHNTQIYTLNDKIFSYTESLAGKREMAIITFKNGAIFQVEVPGSQHIDSQKKAIERMKDTLRIAYLTEAKVEKLCVWNNKTPHAIAAISMAN
The following text describes a protein:
Function:
Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). In association with ABAP1, exerts a negative role in cell proliferation in leaves, possibly by inhibiting mitotic DNA replication. Participates in ovule development.
Subcellular Localization:
Nucleus.
Sequence:
MEVDEDIELQKHQEQQSRKLQRFSEDNTGLMRNWNNPSSRIIRVSRASGGKDRHSKVLTSKGLRDRRIRLSVATAIQFYDLQDRLGFDQPSKAVEWLINAASDSITDLPLLNTNFDHLDQNQNQTKSACSSGTSESSLLSLSRTEIRGKARERARERTAKDRDKDLQNAHSSFTQLLTGGFDQQPSNRNWTGGSDCFNPVQLQIPNSSSQEPMNHPFSFVPDYNFGISSSSSAINGGYSSRGTLQSNSQSLFLNNNNNITQRSSISSSSSSSSPMDSQSISFFMATPPPLDHHNHQLPETFDGRLYLYYGEGNRSSDDKAKERR
The following text describes a protein:
Function:
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLNHWFVLLNTNHFFSFPKTCLRFLMVKFEKKTKYTENSFPVKFEKKIKYTGNKIPDELPHAFFLGIVLLTAVFILYFVGFIFYSAIPVFESQGIINFITGDSWNNGNFGIRNFIVGTLIITAVTIILAVPPSIFTAIFLSEFASPKVVSVFRPLIELLVGIPSVVYGIFGLYVLADILKHVDPIISSIFYFIPFMRDTTPGQGDGVFLSSVVLSIMILPTIITISEDSIRAVPGVYREASFALGATKWETIRHVVLPAASGGILSAVVLGIMRAMGETMAVVMLIGNINRIPSSIFGYTLPMTTKIVTSVGENIGNPDVLSALFGIAAVLFALEILLAGFAKLLVRRCKY
The following text describes a protein:
Function:
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Subcellular Localization:
Nucleus.
Sequence:
MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDRRVIADDEIISLSIEFFHPSRSDRKVTKEKPKEEVNDKRYLRCPAALTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKMSQQRDGLTAAGELESDSGSDKANSPAGGAPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFASRPRKSSVNGSSATSSG
The following text describes a protein:
Function:
May regulate muscle-specific transcription in the embryo and may regulate transcription of a variety of cell types in the adult. Binds to the sequence 5'-CTA[TA]4TAR-3'. Acts downstream of nlk2 in anterior neural development, including eye formation.
Subcellular Localization:
Nucleus.
Sequence:
MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDDQRYFEEETFSKLIEDSDFVFKRDPALNKKENRGCDSPDPDGSYVLTPHTEEKYKKINEEFDNMMRSHKISPGLPQQTFPMSVTVPVSNPNTLPYSSPGNTMVTASLAASASLTDARMLSPPPTTLHRNVVSPGLPQRPPSTGNAGVMLCSSDLSVPNGAGTSPVGNGFVNPRASPSHLGPTGGNVLGKVMPTKSPPPPGGNLVMNSRKPDLRVVIPPSSKGMMPPLNTQRVTSSQGTQPLATPIVSVATPSLAPQGLIYSAMPTAYNTDYPLTSADLSMLQGFNSPGILPLGQVSAWQQHHVGQAALSSFVATGQLSQGSNLSINTNQNINIKSEPISPPRDRITPSGFQSHQHHQHQPRPEMDSLSSSSSSYDGSDREDVRNDFHSPIGLGRPANNEDRDSPSVKRMRMDAWVT
The following text describes a protein:
Function:
Ligand for members of the frizzled family of seven transmembrane receptors.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MRTTLPRCLVLSVCICLECNVALASFGVLSRSKPLVLDSDQNQSVKKFCQQHRKEARLRRFCSVDPGLVQAIVHGTRLTVDSCQSLFQWEPWQCDLLQDKRRHLLKKVYRETALVYALAAAGLTHSVARGCSSGRLSSRCSCNESGSRTLSATESDQNWKWGGCGDNYSFSAKFSRKLLARNKSRRPRTLRRPVDNHNLVVGIRVLRHGIRRVCKCHGLSGSCSAKTCWEELAHFPDVAKALKRKYSKAIMAQVENKPDFASTEVVSKLKKTLLTRTTQKPKWLRAVTAELQRLGRDRLVYLEESPSFCERNVLTGGMSQRRCRDHAHCEQVCCGRGHRSFSETVQERCHCRVVWCCQLECKTCTVLKYSHSCH
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MWREAMMELLDQLEAENPEDPALAPKDLSEWACIYIKYLQIMRKLETAYDQMVHPQKRQDMRKALEACIGRMLEIRHWMVKLNRGLDFINLDDILVDLKLGPEVLEVPVPKYFIEDRAKELDDRDKFLEALIEKYNVKGPAASPIIRIGAPLGEDEAILMIQKNERGRQARERARLAAITKRQRQIEDRRVRLGVTLSHEEAARKIQAAIRGFLWRRRIKKEADKELMFIGMKPKPRDPKRDPQMGEAKNLMRRKRVQLEHGREYDEAIVNLKGKVRELEGQDMRETIQDKVNAWFVEKRNPDTGEYPDFPDPDDGGSRAILNPPPPSLASLLEDAAGDGKGKGKDGKGDAKKDAKKDPKKDKKGGGDEPQAEEQKIGAVFIPAIEAAVQEFVAKWQDRDEADNFHQKYDAELVKDELRPIVFEEIRLQVDGEMRVLLQNLKDLVEAERAAKLGKKGKKKKGKKKEPFSRIKKELLKEAKTLAPGERVLVLGNSREPYLCAKKDEKDAAGDGKGKGKDGKGGGKPGTAGSKPGTADKKKKGGKKKSLCSDWSCGA
The following text describes a protein:
Function:
Involved in the maintenance of the midbrain-hindbrain boundary (MHB) organizer. Contributes to a positive-feedback loop of FGF signaling in the MHB, enabling the MHB to exert its role as an organizer for the tectal and cerebellar development.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MSPWIKHICLVLVAAFMLVKTTESKKDEALYCSACMAIADEINYSISQTDPKKMIHVGGFRLKPDGSLTDKKVPLARSETYLTELLEEVCKSMSDYALYENPDTKEKSYKRFAPRDNDGGNFPDFKNFKFDGPESSSALKFACESIVEELEDDIISLFASDSDHVAKTLCSEVSDHCKSSVFQHSEL
The following text describes a protein:
Function:
Involved in early steps in photosystem II (PSII) biogenesis and in maturation and stability of newly synthesized psbA protein.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Sequence:
MASVPCSFKLSAHRRSSSKLDGNNKQCSSLVERLRDKTKSQVPKSITCINRLEISRIAPLHATMNSPKGFGPPPKKTKKSKKPKPGNQSDEDDDDEDEDDDDEEDERERGVIPEIVTNRMISRMGFTVGLPLFIGLLFFPFFYYLKVGLKVDVPTWVPFIVSFVFFGTALAGVSYGIVSSSWDPLREGSLLGWNEAKKNWPVFWQSFWNSSDKR
The following text describes a protein:
Function:
Catalyzes the hydrolysis of glucose from the disaccharide unit linked to hydroxylysine residues of collagen and collagen-like proteins.
Sequence:
MALRLAGVSLRLLWVLVIAVTGLKPRKPSDTCFVTKELPFHVSTSSITESKAGNFMASIANGYVGTVVMSNSVHVSGLFNGKGWPKRYPIYPIYMSEHAHRARLPSTASISFKVHDNDVVYINGTRSYALDVKTGVFYSWFEETNENGSLFIEMRYYAHRERRNLLINEITIKNDLNKEITLDLSNNYGNFSKDVKLTQHTVSEKEELEIAFGKVNIPEEKFGLQPQVALAFRDIKEHIFINASEWRTWYYITAIATSIDTKFDPWRQAEGAWKEAMRDKRHLLWHHTKAWEELWESGKVDVVTKDKSSHLGQAIYGSLYYLLSSTRADWPYGLSPGGLPGGEEYMGHTFWDQDIWMYPVMVLLYPDLARASLRYRYDRLPAARRIARKWGYKGAMFPWESSLSGIETSPGEKYGRYQNHITGDIAYAAQLYWHATKDYQWLKEIGYALAYQTAEYWASRVSFDNRKEKYVIEYVMPPDEYQFPVDNSVYTNVVAKINLEFAVKVCTLLGRYYPKMWVKIAEQMYIPFDSDRNFHPEFDLYDLGYQAKQADTILIGYPLMYNMSRQVRYNDLLTYENRTDPEGPAMTHAMFAIGWLEVGEEERAAKAFLKNYEHIEQPFQVWTEQRRKRGAINFITGAGGFLQAVLFGYGGFRIREDQLYFDPKLPPTSNTFTITGVDYLGSSLKFIIKNKKMRITLTEREQIAPALELVIYKKVYPLEHKNTLLLLRGPGFIRMRRD
The following text describes a protein:
Function:
Required for loading and maintenance of stable association of cdc45 with chromatin during initiation and elongation of DNA replication. Also involved in temporal regulation of origin firing. Plays a role in meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MNNDHASKKSFCIKAPSNWEKSYLEVWPLVTVPRQCICLRWCISKEYHEFTCSSLQFIVIRPAGTSVLLGRVKSSKANQLVGIEHVEGSRYALIFLSEKLDFKSLKVIANHQLTKSSKSLSNVSNKPLGDQLFRSNSLMSPSLLKKELHRIQSDASQANERESQAPHSFVTHDLISSSKDGNSLTHEFANDSVTEMVQDYTPSCSRDVKSLLDHLYNSYFYQLLMTKTPVVFYVKQMVGKTRQLAVEVHNHVEEKALVDELLKFLDNLKSVDDRKSRLLQCFESHLNYKAWHLEFENEAHQYEIKGYRLWLQNILNRENCQITKLDFEREFSQLKLKEYEIRVLLYFEILYLFLKWDPEYARRRANDNSLLDSRDSGKRKSRKKNAKTLNPFETAQLKLEFTFDGLCIRRTIEQNATERSEDLLLKFCKETIVPYYSSKFPRITRNLLEKCNGLDLLPERSHKHRHSAPPRSKLISSKSEAGRALPGNTSGASISNTSSPHSEASISKDYEILKRRRSNSGVHSLTRSDSSFNGFERDTRRRSSDIARIKNREINLPSSSLSKQRNSMHDISTNFPRRNLSFTEKLTMASLQGQSEESVQPKTTSSLSRSKTLSILEGSVSKRSEPSMDSILVQATPRKSSSVITELPDTPIKMNSLDKASACTVENHIVTESPAHKSNKAQLFVCVPTTPVKKKSASP
The following text describes a protein:
Function:
Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSRGTNLFVAFSISGIVWIVTLFLSTGYVNEVAKSMPTYALILYFSYALFKVGGDLARLKDYPEEAQSLQKEVEEAKRFYKEKGLKL
The following text describes a protein:
Function:
In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links. Blocks inhibition of adenylate cyclase activity mediated by ADGRV1.
Subcellular Localization:
Cell projection, cilium. Cell projection, stereocilium. Nucleus.
Sequence:
MAHSSDTARKDMTNGAHPSAQPGPSGTSTLPRYLHKKQQRQRGVRSSSPMGRVILINAPVDGGDDSEDIHTITVDKSEDGHLGFSVRGGSEHGLGIFVSKVEDDSTAEMAGLCVGDKLVEVNGISLESITMSSAVKVLTGNNRLRMVVRRVGKVPGIRYSKEKTTWVDLIHRRMVVEESGRTPSEASSDGALRRIVHLYTTSDDYCLGFNIRGGKEFGLGIYVSKLDPGGLAEQNGIKMGDQILAANGVSFEDITHSNAVEVLKSHTHVMLTIKEAGRYPAYKEMVAEYSWLNKLANGGQPSSSQGSDSYSSTSSLSSGTPVSSLSGLSQVTFPPAFGSEMVDVCISTEDRSRRPSSERIETAIQTDPQDPDTISRTSRVMSTETSRMVGETVLLKDTVIRRGTAHSRTRTFSAGDKETLDSPKTAVLMALSKPRKAIRRSQSHITVSEFWFATERASCLCGCTSRSRQEDKQKKRKHQKGKVETEGSTLQRSKTFVTLPFKSGRRRERSSSRDRKDTGREDGHKGRSKSPKHLDNEPGKERGRPIINLLSSPRETRAGLREQSPMPSPETMALLEDVARKLLNEDEVAAVMRHCKRFLVDRVVEDLVRPLLAILDKPEKLLLLREVRMIIPATDLGRFDSMVLPFELEAYDILKSRSVRSPVLRSPRHGGTPRRHLITPIPDYRGGFHLQPVQDLERERQLIEDLERMRLAGLPTGRLPPPRAFTPLLDVPVDTYITDSLRNRSLSPARSGFSHSESPYSTERTGRSPLRRDNGFPHDSLSSRGDSVPERGRSPYRNGHRMKTDKSLNGKEVKYTVMSAHRRSRTPLSQVFAPSPEQHWKEPVNGHSDSQDRTEQDYVLTTVTISKTKQSLGISISGGIESKVQPMVKIEKIFPGGAASTSDVLKAGFELVSVDGESLQGVTHQHAVDAIRRAFSNKAKEPMEFIVKVPKRLT
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in proline-rich peptide sequences of plant glycoproteins and other proteins. Hydroxyprolines are important constituent of many plant cell wall glycoproteins such as extensins, hydroxyproline-rich glycoproteins, lectins and arabinogalactan proteins. Possesses high affinity for leucine-rich repeat and proline-rich extensins of root cell walls that are essential for root hair development. Hydroxyprolines define the subsequent O-glycosylation sites by arabinosyltransferases which elongate the O-arabinosides on extensins.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MRSYGKEKKLVFPYVFIACCFFLAIFGFCFFNLFSQGISFSEIPTTRRSVNDETDSLDHGSSVSNIPFHGLSWNPRVFYLPNFATKQQCEAVIDMAKPKLKPSTLALRKGETAETTQNYRSLHQHTDEDESGVLAAIEEKIALATRFPKDYYESFNILRYQLGQKYDSHYDAFHSAEYGPLISQRVVTFLLFLSSVEEGGETMFPFENGRNMNGRYDYEKCVGLKVKPRQGDAIFFYNLFPNGTIDQTSLHGSCPVIKGEKWVATKWIRDQTYD