lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Binds calcium and phospholipids. Regulates microneme secretion.
Subcellular Localization:
Membrane; Peripheral membrane protein. Note=Localizes in a punctate manner reminiscent of vesicles.
Sequence:
MILDKFKNIVNLSNSNTEKEEGKNAEINENNDPNTQLAHEPSIVEADEKTFFDEMLGAPQYTYDEFLQVLKNPIEERGDTEDMKKHWGYPRRWKVILWDLHIQNYMNNDFNAFVDFDFGGNREECRIQRGSTMKIYAKGKTKNCLRTPVVTNVATEQKKNMNFRNVFEYRGSYLDLENEKLRIRVWEYKQFTLNKLEGIYEEPLLSFAVGEIYNETTLYKFIKDSRVKRCRLYFQLYFQELYDFELSFLNWSFSDLLSSSYIQAKSYNYLSNKNNVKKRYIDDTSCNIFPHMCKNFKRFHKKKIYRKVRNYDIDKNFSFNTALSDDSDERKNKNDRTIKNLEKLFVRNLTLMQNIEENEDMSYKNLQNINLPNPRVTITLSHTPKGHEGLNIISIEQKSIRFPIWENLGEIYFRGTLRDLDVSYLNIKVEDMSAPKSAREIGTCQISLKGIVDYPYVMHELEAPSWLVKEAKYEGWENKLNEWKLGTVEGKVIINRVPRYRQRGDIYHIDSKQPYLIVHIFNIDKIITVDNIKELDTYVEVSFDETSRRTRLMKKTLSPNYDSQISIPLRFNNKNDINYENLSKKGLIYIDVWGKSEDIVYIGGISISPYEIFFNEKNVRRNKTKLEHIDLETNVKITYDTVVYRGCKKLCFLHDDQRMSNIHFSIWTYPDILGNSTNQKKIVAPVSFNTTMNFPIKLAEKYNKLKKLFMEVLKTIKSIPENCTDVNTSTRFYNYELINQRKEKHFLPTLITSIKSPYCAESMNAIFHYVRCIPFIHKKENIIFTPDFTLQLKGGNALDHSLLLCSLFLGIPVLAFVCFGTLWDKQKHSWVATFEYNDEKNYGIVKFWETTTGNVYILKKRFIDHNRLKGLELKLKESKYKSHLRNGFLQRYENNTDINYIKEQTKRHIKQLFKNRINDIPIGGPSLPYKTIDLIFNHKNIYVNLQHSSPLNIWYDYWKFDFWFPFSSIEYNLQPSFTIKSFTHKMEDMELDKIAKELRTNIEKNINIYRASRNLSTRWNRDETLEIFLQVGLELLHQLNTSRKEDVLLAKLKIEDWKKALYHKVPQSHRLLGFPYHFNTYKSKFISDKLISTLAILESRDRSLCLSLAVCLYSLPGNFISCYIYIITCVKITQRELRKMEIIKEKAQRMAEIKNSQKKKKSSDDQNIDIKTMDDVEEKETFSSTNLDDTLHDEHTDIDTEKKKHEKDNYKNKKIKNTKLKDANIDNEEKDDHHHITDKKVSKSSDLIHSFDKNDISKNTFDKEEFINNLDKDKKYSSFKKGNVVNKKVSIKNEPSINIYEDHKIYDDENISNNIDNMENNQDEIYNLRQGKTIINEFQQVKKPQKYTINEKRDDIKTKKKRSKEKKKQDKLEFEKLIQSNAYFEQEKKKLQEDIKKLEKDKEQFQKEKIRREEKEKQLLLEEKIKLQKEKELFENEKLERKMSYMLKINELEKKKNERNKMEKSYKRMIQKDKEKKKKKESRDKIRRGEEEKMSADENMKEEQKMREEQKVGEEQKVGEEQKVGEEQKLREEQKMREEQKMREEQKMREEQKMREEQKVREEQKMREEQKMREEQKMREEQKVREEQKLREEQKMREEQKMREEQKMREEEKIREEEQMKREKKMRREEKKKRVQEPIKIDEIQVYDIIKNEKMKKKEEKEEKKRKKKKEDIEDKYKIGKEASLDENNNERQIKSKNIQEISDYEYKNIKENKNLNKFDEKLDLNQIYSKASNFYDNQEKKRRTIKVHANRKENSDSTFSHIDDSIKNKKEYLEDSNIARYLYEKRKHDLIGKGNYNFDEPHYGKKMNNVAYQDIKGSNLFKGFIEEPSSKKSPQKKKIVIVRKN
The following text describes a protein:
Function:
Involved in cytokinin-mediated development.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
Domains SOFL-A and SOFL-B are required for function in cytokinin-mediated development.
Sequence:
MDFSDLDYSDAGDSGWTMYLGHSSSVSLHHFDYHNGETKQEHDEDSSMVSDASSGPPYYCEETVHEDHLQQNTQYWCKSKSKNKNKNKKKVHEEQGYSERFNSSFDDTASSLPVGEEVSAHKQHQNQYQRFHDFCQSYSTRRICKEKVNSGFLQQAFPVDKLALDNQGGDNQRKRRG
The following text describes a protein:
Function:
Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSGETEIDDPEVSDGASENDYSDHEQELDVVGKEDDNQEMAEQKVRPDGDENGNTVGAAATATKPKFDPKDPLRPRRKKARRACFACQRAHLTCGDERPCQRCIKRGLADACQDGVRKKAKYLHDAPPEALRPVLGPTYNQQVSNNRATAASTPTEPSTGMGNFFTQPDTSPSYPLFAANQQGQMPPPLQNRLSFGSNQPSPISPTFHTVGNRPAGMQGISLPQVSNDSHAAFGGGAFFDPSNPALFNFDLEGLNFGNHYGALEFGMLGHMASGSAETPPQDSSAGMPQNVGDLGYNNNPAFNNNPPFNQIYSHDALPDFAVAPPGAHRPAKRQDTKSGPSGKLGPSSALGKRNRDPSSIYDTVHEPYSYTTGFHSLTAFIQKRFSPNKTLRIAKSLASIRPSFISCTKTLNRQDLVFMEKCFQRTLFEYEDFMLNCCTPTLVCRRTGEIAAVNKEFTLLTGWRKEVLLGNEPNLNINTGNSGASSSGSSGRGSFTTPRMRPINLVDSNTASLNSTKILQD
The following text describes a protein:
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Domain:
The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.
Sequence:
MAAITSGDPQAEQIKQFKDFLVSYNKLSELCFSDCVHDFTVRHVRDKEDKCAMNCMEKYMKMNQRISQRFQEFQMQTNEAAIAASQKGFR
The following text describes a protein:
Function:
Plays a role in endocytosis and trafficking to the vacuole. Functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress.
Miscellaneous:
MISCELLANEOUS: Present with 5440 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm, cytoskeleton, actin patch. Note=localizes in cortical actin patches in a LAS17-dependent manner.
Sequence:
MSADLSIGNEIKDSFKETHKWVQNNLKWLKDIEQFYRERAKLEKDYSERLSRLSAEYFNKKSSTSVPISVGDTPTTTPGSIEAAGVVAWNEILSQTDMISKDHDQLSTDFENHVANQLSGLFTKLDMTLSKINGFNNDMVNKKDNIYHELEKAKKDYDEACSTMEMARNRYTKASNDRNKKKLDEKEMEMNKCKNEYLIKINQANRTKDKYYFQDVPEVLDLLQDVNEAKTLFLNDLWLKAASVENDLGANVSKRLQAANSVVKQNKPSLNTAIFIKHNLKNWKEPQDFVYKPSPVWHDDEKFAVPSSLEVEDLRIKLAKAENDYNSLQDKTQNELSKLSTLNKIKHEMKTNEDNINATKFYDTLKEYLNVVSPFTSHETLKLQAEVQIESIQNNVPEEYDLSTDNIDLSKTKKKSGIFSKFKHNILNVDSKPSSGGSTGNGNGGPLHITSLFNTSRRTRLGSAPNNAGEDSDNNSIRTTSTNNTKKTTQNSSDDGKNKVLYAYVQKDDDEITITPGDKISLVARDTGSGWTKINNDTTGETGLVPTTYIRISSAATVKANDRGPAPEVPPPRRSTLPVRTMEAIYAYEAQGDDEISIDPGDIITVIRGDDGSGWTYGECDGLKGLFPTSYCK
The following text describes a protein:
Function:
Kinesin-like motor protein involved in the control of the oriented deposition of cellulose microfibrils.
Domain:
Composed of an N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule) and a central to C-terminal alpha-helical coiled coil domain that mediates the heavy chain dimerization.
Sequence:
MESTECVRVAVNIRPLITPELLNGCTDCITVAPKEPQVHIGSHTFTYDFVYGNGGYPCSEIYNHCVAPLVDALFKGYNATVLAYGQTGSGKTYTMGTNYSGDCTNGGVIPNVMEDIFRRVETTKDSSELLIRVSFIEIFKEEVFDLLDSNSSALLKNDSGVQAKHTALSRAPIQIRETASGGITLAGVTEAEVKTKEEMGSFLARGSLSRATGSTNMNSQSSRSHAIFTITLEQKKIAGGSCTTTEDGGEDILCAKLHLVDLAGSERAKRTGADGMRLKEGIHINKGLLALGNVISALGDEKKRKEGGHVPYRDSKLTRLLQDSLGGNSKTVMIACVSPADTNAEETLNTLKYANRARNIQNKAVINRDPATAQMQRMRSQIEQLQTELLFYRGDSGAFDELQILKHKISLLEASNRELHNELQERRVASEHFSKRAYDAQVEKDKLIMIIESVRNGKSLDEIESCQNEDVGLVNKYVSKIQELEGELLHIKNLKKTSNHQYSDDSYDVGPRSNNVLFPSSNESSDCEDKVMDVTDELEFQEKEIEHCSLQEKLDMELKELDKRLEEKEAEMKRFSSGGTSVLKQHYEKKVYDLEQEKRALQREIEGLRHNLASIPSGPGDGAQKLKEEYVQKLNTLETQVSVLKKKQDAQAQLMRQKQKSDDAAIKLQDEIHRIKSQKVQLQQKIKQESEQFRAWKASREKEVMQLKKEGRRNEYEMHKLMALNQKQKLVLQRKTEEASQVTKRLKELLDNRKASSRETLSGANGPGTQALMQAIEHEIEVTVRVHEVRSEYERQTEERARMAKEVARLREENELLKNAKISVHGDTMSPGARNSRIFALENMLATSSSTLVSMASQLSEAEERERVFGGRGRWNQVRTLGDAKSIMNYLFNLASTARCLARDKEADCREKDVLIRDLKEKIVKFSSYVRYMEIQKADLVHQVKAQTSAMKKLSADENLKNEHSMKKQETRNSTIVLEDMDTSDSEASDHEREDPDLDDEWKPEHESERESEQESVIKLNRKRNFKVGRRRSSVVMRRSYEENSETPSDDAVKSDVCCCTCSKSSSCKTMKCQCRATKGSCGPSCGCSSVKCSNRNADGKENNSISESEALENGENSQESDEKDKGQQQQVLASRGAMLLQNALADKPEEETNDDGGTRRRRKPLSDIGNTTGKSNVPRPSQRKKWKKTVLQLVPVGPPALPPTHTNTHLIPEANSVTVDSDTARMPENSDSGESNSIKLKLPRAMRSASSNGSNLLRERNADQNGSESGGNSGFVQSNSGRASGSRTSDEKENHTRRV
The following text describes a protein:
Function:
Folate transporter with broad substrate specificity. Transports folic acid, folinic acid, pteroic acid, dihydropteroic acid, the folate precursor p-amino benzoic acid (pABA) and the human folate catabolite pABA monoglutamate. Can transport 5-methyltetrahydrofolate with low efficiency.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=In intraerythrocytic stage parasites, localizes to the plasma membrane and some intracellular vesicular structures.
Sequence:
MIEKSNNPFLSIDPIVERTKSNGEGLPLLSEKTKKGFDFTQIVVYLVGLSDGLTHLASLAIYYLFKDYFRLTPYQVSLILMYPYIPFILKPVIALITDSFSIFGMRRKPYLFLFSLFQSLNFLALAFLNLSVIQASLILFFISLCASFCTTVAEALVVESSMGQTYSQGTNKVTEFIASKAIGSLSVAYFSGYFLEKMPREYIFIATSIFPLIISLSCLFLKEKEYSTNRNIFNQLSDLIKFINTPIFLGPFLYIFVYMSGPDYDDAFFFFCTNKLGFRPSFMGTLRLTYGIASLIGIIIYRVFLKNCSLRKTLIITTLVSFPIYISPIILTEHINKFLGISNELFVLSGGFLIEAITEIQLLPLFILTANICQPGLEASVFATILSVKNLGSLTKKGTSSFITYLMKIDSYNFDNLSLYILTCGFFLLFSLTLVPLLPNEEHIEKLKNKETSKG
The following text describes a protein:
Function:
Involved in karyogamy. Component of a cortical adaptor complex that orients cytoplasmic microtubules. It may be involved in anchoring cytoplasmic microtubules to the cell cortex.
Miscellaneous:
MISCELLANEOUS: Present with 656 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton. Note=Localizes to the tip of shmoo projections and to the tip of budding cells in a cell-cycle dependent manner.
Sequence:
MDNDGPRSMTIGDDFQENFCERLERIHNTLHSINDCNSLNESTTSISETLLVQFYDDLENVASVIPDLVNKKRLGKDDILLFMDWLLLKKYMLYQFISDVHNIEEGFAHLLDLLEDEFSKDDQDSDKYNRFSPMFDVIEESTQIKTQLEPWLTNLKELLDTSLEFNEISKDHMDTLHKIINSNISYCLEIQEERFASPIRHTPSFTLEQLVKLLGTHTETTEPKVPKFSPAEDILSRKFLNLKKNIPPIEKSLTDILPQRIVQFGHRNITNITTLQTILQKKYELIMKDYRFMNSEFRELKVELIDKRWNILFINLNHELLYILDEIERLQSKLLTTKYTKDITIRLERQLERKSKTVSKTFNIIYRALEFSLLDAGVASKTNELAQRWLNIKPTADKILIKSSASNKIATSKKKIPKPKSLGFGRPNSVIGTITQDFQERVAINEGDSNKTPENSTTVALKGKKLGKALLQKMNIKPATSPNSSNAINPFFDPESPNKGKLILSSVPPLPYDETDETTLRVSRGENEKSPDSFITSRHENKVQITETPLMAKNKSVLDIEKDKWNHYRSLPSRIPIYKDKVVKVTVENTPIAKVFQTPPTKITTPNSQVWVPSTRRRTRLRPPTPLSQLLSPREGRLDKTPTY
The following text describes a protein:
Function:
Binds specific group II introns in chloroplasts and facilitates their splicing. Acts on subgroup IIB introns. The substrates of the subgroup IIB also require the CRM domain proteins CAF1 or CAF2, with a simultaneous binding of CFM3A and CAF1 or CAF2. Required for seed development. May influence the biogenesis of the mitochondrial small ribosomal subunit.
Subcellular Localization:
Plastid, chloroplast. Mitochondrion.
Sequence:
MAMKPSLHFCPTTVTKKFVYSFQSSFCFRFLRYSSSISLGSCKGVTFSSRNDQIASRRFSFSRDCNNGVWLENWNRIQKRNQPKPPKVVVNYRKEGRFSGSEIVSGDDNRSRDGDGSTMEKIVEKLKKYGYMEEVQNKEIEQERRIEKGSVEDIFYVEEGKLPNTRGGFTEESLLGGENVIGSNGDVGFPWEKMSAKEKKELEAEWTAKKENRYSLAEMTLPESELRRLRNLTFRTASKMRIRGGGVTQVAVDAIKEKWKSAEIVRLKIEGASALNMRKMHEILEKKTGGLVIWRSGTSISLYRGVSYELPSGKWNKQRREETPPEAVIENHDETTTMVDKSDEKVHLPQLEQETTSVEKKDQTSPVVEYEDELDELLDDLGPRFMDWPGDNPLPVDADLLPGAIPDYEPPFRVLPYGVRSSLGPKEATALRRLARSIPPHFALGRSRQLQGLATAMVRLWEKSMLAKIAIKRGVQSTTSERMAEDLKKLTGGIMLSRNKDFLVFYRGKNFLSREVADALVEQERFVRTLQDEEEQARLRGSSALIVPSTEPANKLVSAGTLGETLDATGKWGKNLDDDDHSDEVKQEVEILRHENLVRKLERKLAFAERKLLKAERGLAKVEVCLKPAEQREDPESITDEERFMFRKLGLKMKAFLLLGRRGVFDGTVENMHLHWKYRELVKIIVKAKTFDGVKKVALALEAESGGILVSIDKVTKGYAIIVYRGQDYKRPTMLRPKNLLTKRKALARSIELQRREGLLKHISTMQAKAKQLRAEIEQMEKVTDKGDEELYNKLDMAYASSDEETDEEDDDDAFPETYAEGEDGEEGEILAGELSETEDKDLDSNESETGFGDDSVLFAEDLHTKSEDLPNKKVRLQHQS
The following text describes a protein:
Function:
Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition. Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for STAT5.
Subcellular Localization:
Cytoplasm.
Sequence:
MASSAQSGGSSGGPAVPTVQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMRANNPEQNRLAECEEQAKAAKKGMWSEGSGSQTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKDGFARCVDWSIAVYTRGAEKLRAAERFAKDRRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVAPMLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGTLPPAFSTRVLPAQATEYAFAFIQVPQDEDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR
The following text describes a protein:
Function:
Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
Subcellular Localization:
Nucleus.
Sequence:
MAETAAAHPPSSVEQLVRTSAKRTRELFAADFASSAALDHAANPAFTITPSTASPSSTADQVNVATRIRNEYEHVRELPPALAAKMAAAATTAAERRKKIKSQNAEEKASDPKMQKIIEGASEKADKARDSQSMQLALRAGGKGAAPNATGPTPMRDTPSSALVRKDTVRQARPEWHRPWKVSRVMAGHLGWVRSLCVDPDNQFFVSGAGDRTIKLWNLATGELKITLTGHISSVRGVEVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYSLSLHPTLDVLVTGGRDGVARVWDMRTRTNVHVLGGHKGTISSIKCQEGDPQVITGSMDSIKQWMCPRGDFMLNFQPVNSIINTLSVNEDNVMFAGGDDGSATFYDWKTGHQFENSESVVQPGSLSAEAGILTSTFDRTGLRLITGHIDKTIRVWKEDEDATEETHPLDWKPTLGRQKF
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs.
Miscellaneous:
MISCELLANEOUS: Present with 861 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MVGGALICKYLPREEQLKLISDLIQNDSLEEVLELIETSPLDITTDSNIETPIFEKITEQVIAYASIDGEAREMFRSSRAEMNKALRTSAQLLCCLPSVWHKFQVWMSYRLNDIISENYKHLFNDNFGKKIVQPFFDSFAEEQNANIKHENLHLDILSLLHYLEVVYLFDECKNGISSKCLDFIIVPLLGCNSEEIADSCSKLMRWHIKYLSKCCNTDSNFDKLIWTFIKQLYAEGSQQAWKQKNSLSFLLRFLLAAELSPELITYIKTDAYWRHIQTELDNDVHEHRKLALSILKLTIQKLSSHGITLQTTFYKCNDLANIEMLGSWKKFTTLYEMIALDTSLNQIQAAKQDIIKIFDNEHLHHSWGLILLSTGLKSSMESVRKYMMTLMFSITNMSAFSSNLPLLTKTLLPAAMSAHYFDVKGVSCPHGEKLSLFVNNLLSQTTEGISDILFEILKLLVEKGTSFDPSRIYLSYGILVFFQNNKQKTINSDHLSLIRKLYDFAAEEEVLETTIQTIYLKFLLYIDPSVSASELLFTLVSHIKLKGGTYKYVEPLFEDYRDLAVSHFDDLQAKENLTTNIGKDTIFDLLASIIFDFKDIDITPDFLIEVAKSKQDIPVYTSKAVTFLTQLLSGEPSNGYTYENATALLSYPNFTISTWKSINVNNLFKSVMEKFSLDKFKFFAEIYQKTYECRFDTIELNFNDLLSLYEMVKKSANQCSRESFKVKDSAYSSYFELLNTFLKTYALNRDSSEGNDDELHILLRLVDENINKDNGNYLGNLAVCKLLYFIIDSYIHCSTSVSDDDIFIVKFIFEKFSFIWECINSERLVLKERDLHLMLIKGLFHPVILYFGSNQYIDTLTSKLEEHAQTIISLSYSRRSLLPLLGSQLRVFMKFYGKLLREDVNYWWLINIIVGVFKQPQMDVNLYKLKPVISSLFDHKLNNYYIKGDELYEKVYGPDEILARVSIIDSILYANDQLKIRLIEKVTEKTNALYAIKRTDGAEALQRLLQWQLLLLSLLTTNEKKLSETSMIRILKSIEDESSPLVRVYKEWFISSKVVDYYKTGNPKFAEDYLFSLLEDHSKPVFVVSAEKICFMVLKDLRNDEKKYGFTQLLDRFICTLVPNAASNKPLVRHFSNSLIISLWPTFKAYLSDHTLRNIIENLYSNAKKTQIFGQYRAGDANIWDLKGDRKLTNMFGGVLKKVTDHDCPYISESVFEKYLQEKDIVPIGTDERSLWLDKRDTNTESVNNANISCDTSPLQTKSGAWETVLDLDNKKSNDVVTRSELIVVSSLVDKPPNLGGICRLCDVLGVGLLTVQDIKVKNHPQFKNVAVTADRWMPMEEVALDEIASFMKEKKKEGYTLIGLEQTDKSVKLDNNFQFPKKSLILLGTEAFGIPGTLLSELDLCLEIQQFGVIRSMNIQTATAVIVHSYTVQHM
The following text describes a protein:
Function:
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Subcellular Localization:
Nucleus.
Sequence:
MSSKSGSTRKSQRARDFEESEETEKPSLTRRKSSRLSTQSVPIEKKKTPSSKTTKRVPVSERVFHEEVESSSEDELLPQTKMASEEKRKLLLSPGSSLADRVEKLEISSPRARGRPRKATNLKSQLTTPRTPEKQSRSRSGSQGTPEKKSRKESSSESDSEEIISTSSEGALKGRREEFDSLKLWIMKSKETNTSLSIYVSGQPGTGKTATTMRVLKSLGKSVRSCIVNCASTNTKSALFKTIFESLDLDGKPNEEIFEKHVKQFKTPLVLVLDEIDHLANRKNAALYAAFQWPETLSRKIIILGIANSIDLTERLLPKLMLAKPPKRLVFEPYTKDDIVEILNDKMKNEETSIDAKAIELTARKVAAMSGDLRTALHIFKQQKSRMIPDDSKVPGTPVNGCREVLGIINNVYSSPLARARLPLQPRILLAVSLTLSANKKCTFDRNSLLRAYYKACEALRMPALDDDELHSAFQTLESQSFVRQLNGGKLVLQVDAPTAKSAISDNAMLDQIGLLQF
The following text describes a protein:
Function:
Ubiquitin-protein hydrolase involved in the release of ubiquitin attached via both peptide and isopeptide linkages. Able to cleave 'Lys-48'-linked polyubiquitin chains. Involved in the direct or indirect regulation of AUX/IAA proteins stability (Probable). Acts as a linker between the TREX-2 complex and 26S proteasome.
Miscellaneous:
MISCELLANEOUS: UCH1 and UCH2 are not integral polypeptides of the 26S proteasome, unlike their S.pombe and animal orthologs. However, they interact with the 26S proteasome lid complex as well as to the TREX-2 complex.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MSWLPVESDPGIFTEIIQQMQVKGVQVEELYSLDFNSLDEIRPVYGLILLYKWRPEEKENRVVITEPNPNFFFASQIINNACATQAILSVLMNSSSIDIGSELSELKQFAKEFPPELKGLAINNNEAIRAAHNTFARPDPSSIMEDEELAAAKNLDEDDDVYHYISYLPVDGILYELDGLKEGPISLGQCLGEPEGIEWLRMVQPVVQEQIDRYSQNEIRFSLLAVVKNRKEMYVAELKEYQRKRERVLQQLGALQADKYAEKSSYEALDRELSEVNIGIETVSQKIVMEEEKSKNWKKENMRRKHNYVPFLFNFLKILADKKKLKPLIAKHHP
The following text describes a protein:
Function:
Catalyzes several different glutathione-dependent reactions. Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE. Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB). Catalyzes also the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (LTC4). Involved in oxidative DNA damage induced by ER stress and anticancer agents by activating LTC4 biosynthetic machinery in nonimmune cells.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Sequence:
MAGDSSLLAAVSLLSACQQSYFALQVGRVRLKYKIAPPAVTGSLEFERIFRAQQNSLEFYSVFIISLWMAGWYFNQEFPMMDLNEADCLEEKVLGFCNLSGSPVHIRPSQVFLGLCRSR
The following text describes a protein:
Function:
Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation.
Subcellular Localization:
Secreted.
Sequence:
MIPTTILISAALLSSALAGPWANICASKSSNEIRTCDSYGCGQYSAQRTQRHHPGVDVLCSDGSVVYAPFTGKIVGQEKPYRNKNAINDGIRLSGRGFCVKIFYIKPIKYKGSIKKGEKLGTLLPLQKIYPGIQSHVHVENCDSSDPTAYL
The following text describes a protein:
Function:
Involved in the digestion of the blood meal.
Subcellular Localization:
Secreted.
Sequence:
MRFPVLVAVLCAVIGGTAGRQSYSGYKLYSVEQNNQQQVDFLRELQQSAQDLDFWQLDRLVGSEARVLVPPAQLDYFRQLLKAQKLRHRELIHDFERVQDDHLYGTKRVTPSQGLPLNKYLRYNEMIDYINTLAKKYSSFVTVAEIGKSYEGRPIPAVTIQSPSLYKSHPNSSKPVVFVDAGIHAREWAAPAMAMYLISELVENAAQHQDLLAGLTWTIVPIANPDGYEYSHERERLWRKTRRPAGRNCVGVDGNRNYDFHWAEVGASNQPCSDTYHGEQSFSEPETRAIRDELLRLKGRCKFYLSLHTYGQYLLYPWGWTSELPEDWQKVDAVARAGARAIEQATGSTYTVGSSTNVLYAAAGGSDDYAYAVADVPISMTMELPGGGSQGFNPPPTRIEEIVKETFVGVRAMALEVARNYS
The following text describes a protein:
Function:
Involved in trafficking and recycling of synaptic vesicles.
Subcellular Localization:
Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Early endosome. Golgi apparatus, trans-Golgi network. Late endosome. Membrane; Multi-pass membrane protein. Recycling endosome.
Sequence:
MNFKSLSPLTTEFDNGRTSTSQISLLPTMSLHSITEYLDDLKMSRRRGRDYDHVDYTKLAPADKDNGFIDAQFITPAQKVPWKAICLATMLLVVGTFLLIFGSLVVSGHIILNYSDRMWPMIILGLLMFIPGAYHVRIAYYAYKQVPGYSFDDIPEFD
The following text describes a protein:
Function:
Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Sequence:
MTETTIRGHKGMTSVKEMSVLQDGPPPGGFPAVRYARRIANTGPSGVTVLLVSSAIISWGMYQVGQGNIYRRGLKAEKIAARQAILPLIQAEEDARFVRENNKLLEEEAKVMANVPGWKVGENVYNSGRWMPPSSGKLGMDS
The following text describes a protein:
Function:
Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Probably does not act as global transcriptional repressor, instead targeting a subset of genes. Involved in RNA processing mediated by Tar DNA-binding protein homolog tdp-1. Plays a role in linking epigenetic regulation with the innate immune response. Involved in the endoplasmic reticulum (ER) stress response via modulation of the unfolded protein response (UPR), acting mainly through the IRE1-XBP1 pathway and perhaps, to a lesser extent, through the autophagy pathway. May act in a common pathway with retinoblastoma-like protein homolog lin-35 and zinc finger protein lin-13 to influence the ER stress response in the intestine. Plays a role in the formation of the vulva and in fertility, acting together with a CoREST-like complex, and chromobox protein homolog hpl-1. Acting in concert with hpl-1 and histone H1 protein his-24, involved in reproduction, somatic gonad development, male tail development and vulval cell fate specification; perhaps as a result of modulating expression of Hox genes mab-5 and egl-5. In vulval cell fate specification may act by repressing transcription, of EGF family gene lin-3 in hypodermal hyp7, and of homeobox lin-39 in vulval precursor cells (VPC). Role in growth and somatic gonad development is antagonized by histone-lysine N-methyltransferase set-2/SET1. Required for larval development, acting redundantly with hpl-1. Plays a role in regulation of the developmentally arrested larval state known as dauer, longevity, and lipid metabolism.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to distinct nuclear foci, not overlapping significantly with hpl-1, in embryonic cells. Localization to nuclear foci overlaps partially with zinc finger protein lin-13. Localizes to foci in a lin-13-dependent manner. Localization along chromosomal arms correlates with localization of histone H3 methylated at 'Lys-9' (H3K9me), however, hpl-2 can associate with chromatin in an H3K9me-independent manner. Localization on chromosome correlates with sequences enriched in repetitive elements, or in well-expressed genes. Localized to gene bodies.
Sequence:
MSSKSTKRAKIEDPKDNVFMVEKVLDKRTGKAGRDEFLIQWQGFPESDSSWEPRENLQCVEMLDEFEREFSKREKPIRKRHSQKPEPSEDQADPEEDKDEKKETNQNDKFSLEGKQLKCIVGLTKGPGELHFLCKFSDDTARLLPAKEVNSRYPSQVIRYYESKLTIQDPKADEL
The following text describes a protein:
Function:
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MNKLQSFLTRGQDFWQKFYEKKGKKGVAQVAALGLGLLYLQYQVRKHNGWLKKKSVVNEHIFITGGASGIGKNMALRFARLGAKISIVDVNEDALNQVVGQINSLHGEKAAFGVKCDVSDPQSVKNAIKKCIDFHQKKIDILINNAGVVSGKQILENTDAGIARTMNINTTAHHWTVREVLGDMIANKHGHIVTIASIAGWVGVRGLADYCASKFGAVGFDESLRFELRATKSNVKTTCICPYFINTGMFDGAKSKFPLLFPILSENYATTRIVNAVLQDETVVIMPIILNLSIMVKAIFPTCIYDNMMELFGVSESMDHFKGRQQ
The following text describes a protein:
Function:
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
Subcellular Localization:
Cytoplasm.
Sequence:
MKIAQELRAGSTIKIGNDPFVVLKAEYNKSGRNAAVVKFKMKNLISGNISDAVYKADDKMDDIKLDKVKAIYSYQNGDSYIFSNPETWEEIELKGEDLGDALNYLEEEMPLDVVYYESTAVAVELPTFVEREVTYTEPGLRGDTSGKVMKPARINTGFEVQVPLFVEQGEWIKIDTRTNEYVERVKK
The following text describes a protein:
Function:
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MPTTTTTAEDGFPATGRLASVDYGTVRIGVAICDPDWILASPLEVHPVSTPEKDAQYFIDLAKSERIAAWVVGLPIHCDGGESDKSKESRKFAAWLKETTGLPTRLFDERFTTVAANAKIRQGKTTRKKTKQRVDAVAAQVLLESFLEACRYRGELAGHCLEDSTSDESLDDA
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLRKGVSFVGQAVQQTLKTQKNLRIQRFSATASQSSEEVNYEIRKDGKRLRGADYEEIVLTSIAGEDKTQIPKGAFDVLLKEYDDLQAESLDFKDKYQRSLAETENVRRRGIKQTDDAKVFAIQSFCKDLLEVSDILDIAVKSVKPEDLESGGKALKDLFEGVSMTRTVMAKTFAKHGLVTVDPTNEKFDPNLHEAVFQIPSANAKQPVGHIEVCTKIGYSLKERPIRPAQVGVVSK
The following text describes a protein:
Function:
Mediates both basal and acquired thermotolerance. Involved in the mechanisms necessary for quick response to heat and subsequent heritable transgenerational memory of heat acclimation (global warming) such as early flowering and attenuated immunity; this process includes epigenetic regulation as well as post-transcriptional gene silencing (PTGS). In response to heat, HSFA2 is activated and promotes the expression of REF6 which in turn derepresses HSFA2, thus establishing an inheritable feedback loop able to trigger SGIP1 and subsequent SGIP1-mediated SGS3 degradation; this prevents the biosynthesis of trans-acting siRNA (tasiRNA) and leads to the release of HTT5, which drives early flowering but attenuates immunity.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MALPPYDPNFTLAFSYGRRDNVFENDPEHDESASAAIVAVELISSARLALKLDSVRTEYSAQYLVDKAGSRNLRRRRKLTVKDCLNFALKKGGIPRAEDWPPLGSESKTPSSYEPALVSMKGEVIEPKDMDEVPELLVHQSAVGAKLHVFTPHIELQQDAIYLPRQVSMRATLDLEMG