lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable transcriptional regulator involved in cell adhesion.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MADFMDIEPSSHSAKASQYESSAPASSSLGNSHPNESLDYYIYDYFVKHNFEEAAQAFLRESKIQIPKSSSSTAFSPSNNNAPSPFPPKNSSLASPSKISESISGDRLYNHMSSAPSPNKKEETNVVHANEDISLDKRQSFGSSSLPPSEVSINVPEGFLVEWFNIFWDVFSARVSRVNSTPIQLYDPSTQRQMARPMSNLQASQPVPSSTFSRSAVVPNPSLPLNPSVLQGQVMNNPTIPKGTPSTSIEGAKTSIPPSHAMQNPHNSFPASADRLQKNHPVQSSNFNPYTPAPSITVPPNYIPNTAMMGPSYSSFGDTDPRTYPAGMGPNPTAARNGFYPPTPAQIHQLKAQQQHLQRQSKQMSEPAPINMKSNKDQQLQYVDFRGVGSGADLQKQQWNKSTSAEGLQPNGLVMRNFGDVRHQKLPTSSPPSQHPPVGQIPSQYLPYQAGLKVPGNTPIPVKQVGGMPLQSPLPVSMKPSADDHSRATPTRSVEAPTLPSYAPRHPTQANGSRYMNPSTSRMTPQSPYMQNYYRPHAQMQDQNNMMSYMLSQQKAMEIAKSREMAIQRNTQTLSSGNQPPQQSGPNPNEFSMSMDPANMQQGNHALSDYHMQLMLLEEQNKKRLMMARQEQGTGSLSPQSYMNSRYSVDVGKEHMSMIPNQTAPMIQPNVPVSANSPAQANTPAADSTKSGTIQPTNRNGEGLSYSPHQQFSPSAPQAEKLSRSMSPFVSQQQQLNQPVSNKPDGLTQNKEVTGMPLNKEELTNPAFPQSRTSWMMPQSFDTSSLNAPGAKDSSSFSSLHAQPGKSGIATMGVADNTIRTTERSTFSEIMKDSPSAHASPGAKTSPNASRAPEPTGGTNSISQDTTQSLQMQSNSVNSSSMVDASKSKEKSGGDTSALDSNAKNEPTAAKPISKLEDDALFNDSAGNAFGFSSKTDSNVEMLNDFDFESFLNDAGADSASVYY
The following text describes a protein:
Function:
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
Sequence:
MALLRWRRTRMVTLISKGGRNFKMPEAVALVSSRSCREALDYIEYRGNNTMMIKLLDIDPKPVSMLVNFCNHMAAAATSAASDDAAQRMREWEERFLGDDVDQALLYDLLSAAISIQADGLIDLVCKRVAHMIKGKTPQEIRTILGIQDDLTPDQRDEIRTDNSWIDI
The following text describes a protein:
Function:
Probably involved in mitochondrion division process. When overexpressed, induces mitochondrial tubule formation. Binds to and hydrolyzes GTP (By similarity).
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MSQFMIRYQIINLSKVFNSPKSLNFIKRYTTSTASTTTTTTNDDSNWISTPNITVCGIGGGGCNSVNNMINKELYGIDFVVANTDAQALAISCSRKMVQLGKTLTRGLGAGAVPEVGKKATEESIEELMNQIGDTQMLFVTAGMGGGTGTGGAAVIASAAKAKGILTVGIVTKPFHFEGKHRMKLAEQGLIELEKSVDSLIVIPNEKLMEQSQELYIGNAFQMVDDVLYNSIRGISDILVKPGLINLDFADVRSIMCNSGKALMGVGEGEGKGRDAIAANIALNNPLLENINISGAKGVLLNIAGSDLKLQEVDHIVSLVSSKVDPSANIIFGSTFDQQLEGKIRVTLIVTGMDQLIQQQQQQQKQTKIESQVEQKLHSTTIVDQELKPIEPQKSIIIEEEQEEQQQPKPIIPGIFVEQELLTTTTTANITPSQQKQESLTQNNIFSPPQQQQQQPSINLQPNYQQLYQQLYQQQQQQLQQQQPISFLKRLSNLFFTNGNNNKPYNNNKNTPGSNYE
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.
Subcellular Localization:
Cytoplasm.
Sequence:
MSDMSEQSVEIASSQLGTKDFWDQRYELELKNFKQHGDEGEVWFGTSSETRIVKYLIDSKTGKDAKILDLGCGNGSVLRKLRSKGFQSLKGVDYCQKAVDLSAAASKAEREEEEDEELVDIEFEQLDITTPPADFFSSKFDVILDKGTWDAMSLSDEREARLKAYLGFLDNGLSAGGRFVIFSCNFTFDEMCSQFGGGGGSTSLEIVCEVPASHSFSFGGKQGVTSTGAVFRKKTL
The following text describes a protein:
Function:
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons.
Subcellular Localization:
Nucleus speckle.
Sequence:
MHHHISQDPSRSTTPEYQESPSQKTSDSTKKPPTLAFGMWRADNQKKFDEMYPNKLPFEVVTKMKTAWRHHIPAEERDYYFAKERQLKIQRDNPSMAPTKVESPPRSFEVAREVESPKPQEEYVKRPLNPYMIFFRKRRADMSITEPNLPSSEICKRLGAAWANMSAAEKKPFYDEAGKLKKQVYEEHPNYKFHPRKRPAAQISETPTSTMTPIRPTSYSIPHGPPSHSQPSSPMRQSSFNMPPQQVQTPHTPSNVPPPGVPAQRQQVRFRFPPCLEYPRTSGRAIREGQENYGASYLPVWF
The following text describes a protein:
Function:
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
Sequence:
MTSSATSPTNGVDKNKNEEMVATPANCPYQLFNQEVVWNGKWIQTRQVGFKTHTGQVGVWQSVHRNTKPVEASADGVSIIARVRKQGKLYIVLVKQYRIPCGKLCLELPAGLIDAGETAQQAAIRELKEETGYVSGKVVMESKLCFLDPGLTDDSQCLVVVDVDGDAPENQNPVQVLDSTESIEVLLVEQSALMAYVTNLDSSSIVVESTLLAYAMGIQFATI
The following text describes a protein:
Function:
Subunit F6, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MILRRLFRLSSVVQSAISVHLRRNIGVTAVAFKELDPIQKLFVDKIREYRTKRQTSGGPVDIGPEYQQDLERELFKLKQMYGKADMNTFPNFKFEEHFFQRLRGWQASRLRDDAILIFHH
The following text describes a protein:
Function:
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids.
Miscellaneous:
MISCELLANEOUS: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.
Sequence:
MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MSSAAPPPPQPESPSAGAGAGGGGDKVLAAAQHIVKSLATSKNAADDMIRILSGFDNRLSSITNDHLFPSPDPSSGPASGSASASGSSASEISAAAAFDAADQLIQLWDATPEALVFEAPEDDVAQYLAAVDVAVDHLARGGPGGARAGVAVQLAMARLEEELRHLMVRHAVPIDPTGLFFSLRRLSLESMDDLDASSEFDAATPHSLDGTPAGPETARGAVLGSNPFEDQVFDPVRPEAVDELRAIADRMARAGYSRELADAYCGVRRDVLDEYLSVLGVERLSIDEVQRIEWKLLNDKMKKWVHGVKTVVRVLLAGERRLCDQVLTASDDLMEECFLESTKGCIMQILSFGDAVAVCPRSPEKVPRILDMYEALSEVIPEMRDLCIGSSGDGVISDVQAILDRLGDAVRGNLFEFGKMLQQETSRRAMTAGEIHPMTRYVMNYLRLLVVYSETLDVLLADDNCDQDAFRNSDDQDQEHLQSMTPLGRRLLKLISYLEANLEEKSRLYEDAALECIFAMNNLLYIVQKVKDSELGKILGDHWIKRRSGKIRQYSKSYLRISWTKALSYFKEDGHGSGSGSGSGSGSGSGSGSGSGHSSSRMSIKERFKNFNMAFEEIYRNQTLWKVPDPQLREELKISISENVIPAYRAFLGRYGNQVDGGRNPGKYIKYTPEDLESQLSALFEGSSVSANHSRRRT
The following text describes a protein:
Function:
Facilitates the release of the SAR-endolysin.
Subcellular Localization:
Host cell inner membrane; Single-pass type I membrane protein.
Sequence:
MDLISVLALWPYLLPVVAGGAVWAMRRSFASTERVERLENRMTEMETRYASIPGTEDVHEMRLRIAELSGDIRVLSQRVQSFSHQLELLLENAVNRSNS
The following text describes a protein:
Function:
Acts as a negative regulator of the type III secretion regulon (T3SS) expression. In the absence of inducing signals such as low Ca(2+) or host cell contact, the T3SS/injectisome is expressed at a low basal level and exists in a quiescent state due to ExsA sequestration by ExsD. ExsE binding to ExsC disrupts the complex between ExsC and ExsD, thereby allowing free ExsD to bind ExsA. Upon inducing signal, ExsE is secreted allowing ExsC to bind ExsD. In turn, ExsD cannot bind ExsA and prevent ExsA-mediated transcriptional activation of the type III secretion system.
Subcellular Localization:
Cytoplasm. Secreted. Note=Secreted under low-calcium conditions.
Sequence:
MKIESISPVQPSQDAGAEAVGHFEGRSVTRAAVRGEDRSSVAGLARWLARNVAGDPRSEQALQRLADGDGTPLEARTVRRR
The following text describes a protein:
Function:
Extracellular metalloprotease that contributes to pathogenicity.
Sequence:
MRGLFIVLVCIVSAFAAKDYSGYQVLRVTPGTDEHRQWLRELETSMADEIDFWSDIKNIPGSTVDIMVPKRLRATFLDIFAVKKMQVSIMIDDVGQLIHEQDEERKERRATTQDLTSFDYTVYHPYDEIQQWVTDIVDAYPTIATRFELPRTSYEGRTISGIQIKGTGGSSGMRKGVYFEGGIHAREWVSPATVMYITKELLQDFMDGDATAVRFFDTLDWYIVPSLNADGYVYTWTDDRMWRKTRSSNEDHALSGCTGTDPNRNWPFGWAGSGTSPFPCSNVYHGEYALSESEVEAVVDFLREKKDNGQDFVWFIDWHSYSQLVISPWSYSATVPDPDNLDDLQAAGEAMAAGIASHTSGTVYEVGPTAKLLYEAAGASNDWGYAPYDTFDKTEGGLGAPYSYVVELRDTGEYGFILPDTQIEDSGKESVLGVYAMGTYILDAEGL
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Sequence:
MARLWGSIFILVFFSLVSSLELVSSASEVTSSRSKAIASFQSWVDRVGANHSAFENTAKSSGSTGDLSRKVAEGVIVVDQSGAGHYKTINEAINAVPLHNKYAVTIKVNPGIYIERVMVPKSKWRITLQGSGRDVTKITSRNAAGDTGTTYTTSTFGVSAPYFTARNITFENSSPLQIGGAQQQAVALRTTGDFNAFYGCAFLGQQDTLYDDRGRHYFKESLIVGSVDFIFGDGKSLYQNCELRVLPSSGGSLTAQKRLSFSEDTGYSFVNCKITGSGPSTVYLGRAWGPYSRVVFAYSEFADIINPVGWYNWADPARERTVFYGQYKCFGPGANEASRVGWSVELTDAQAAPFMTLGYIDGGLWVTEE
The following text describes a protein:
Function:
Serine protease inhibitor involved in antimicrobial egg defense preventing contamination of table eggs (non-fertilized eggs) and protecting the chick embryo (fertilized eggs) (Probable). Inhibits trypsin, chymotrypsin, elastase, subtilisin and a proteinase of fungus Aspergillus oryzae. Inhibits calcium-activated potassium channels KCNMA1 (bovine) and slo (Drosophila). Has antibacterial activity against B.thuringiensis LMSA 3.06.004, but not against S.aureus CIP 103 811, P.aeruginosa PAO1, B.cereus ATCC6464 or B.subtilis ATCC 6633.
Miscellaneous:
MISCELLANEOUS: Prevents symptomatic gastoroenteritis in vivo in a mouse model of rotavirus infection. Significantly inhibits intestinal replication of EDIM strain of murine rotavirus in infant mice up to 4 days after intragastrical administration of the virus.
Subcellular Localization:
Secreted.
Domain:
Seems to have at least five separate non-overlapping active inhibitory domains; two for trypsin, two for chymotrypsin and one for elastase. They can be bound to the domains simultaneously.
Sequence:
MTDWVLHHKVGPLDMTTRYIFPLLPLPFLPHSESKRAVCAPRCSAMRTARQFVQVALALCCFADIAFGIEVNCSLYASGIGKDGTSWVACPRNLKPVCGTDGSTYSNECGICLYNREHGANVEKEYDGECRPKHVTIDCSPYLQVVRDGNTMVACPRILKPVCGSDSFTYDNECGICAYNAEHHTNISKLHDGECKLEIGSVDCSKYPSTVSKDGRTLVACPRILSPVCGTDGFTYDNECGICAHNAEQRTHVSKKHDGKCRQEIPEIDCDQYPTRKTTGGKLLVRCPRILLPVCGTDGFTYDNECGICAHNAQHGTEVKKSHDGRCKERSTPLDCTQYLSNTQNGEAITACPFILQEVCGTDGVTYSNDCSLCAHNIELGTSVAKKHDGRCREEVPELDCSKYKTSTLKDGRQVVACTMIYDPVCATNGVTYASECTLCAHNLEQRTNLGKRKNGRCEEDITKEHCREFQKVSPICTMEYVPHCGSDGVTYSNRCFFCNAYVQSNRTLNLVSMAAC
The following text describes a protein:
Function:
ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MAGPLSVEDMLAKQKAEKEAAAKPKFLSKAERQKIALEKRQSEVREQQEREDAERRQREEFDRAAEEERRRHEQERYGYNAGPSGRNDRDGYGRDGYGRDNRRGFGDRRDGSGPAIPSGPRGAALPVGPRSMQSRNGGGLPYDGFAQGSPSQLSSTPVAGSASPGPASTTASGDAVPPSQAELEALRARYLGKRTDGKKPRLRKAQDKKIIFDWNEQDDTSAADQSSWTREVRELVPGGTMFGGRLAGMDGAKKNETRSDNHADPLERRRAVKGKDDDRHWSDKPLDEMKERDWRIFREDFSIAARGGGIPHPLRNWRESAIPSQILDIIEEIGYKEPSPIQRQAIPIGMQNRDLIGVAKTGSGKTAAFVIPMLDYIGHLPPLNDDNRHLGPYALIMAPTRELAQQIETETRRFALPLGYKCVSIVGGRSVEEQQFALRDGAEIIIATPGRLKDMVDKSILVMSQCRYVVMDEADRMVDLGFEVDLNFILDSMPATFVKPDDSVALQPTKEGEWQGWRVTTLFSATMPPAVERLARKYLIKPATVVIGNAGEAVDTVEQRVEFVHGDEKKKARLIEILRTIGLPPPIIVFVNQKKTADMVVKYVQQAGMSGVTLHSGKSQEQREAALQALRDGEISVLVATDLAGRGIDVPDVSLVINWQMSDTIEKYVHRIGRTGRAGKTGVAITFLTNDDDEVMYDLRIEVEKSKMSKMNPELARHEAARTRVTREMKRKRGDEEE
The following text describes a protein:
Function:
Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAPKYFTSLRPHLPLLVLLLETAFILVFFFFASYDAKNPPDLHLYPEFQDVHVMVFLGFGFLGTFLARYGFSSSGFNVLVAAMTAQWAVLMNGFLFAFGNRTIVVNLRSLLTANLCAVSAFVSMGVVLGKTSPIQLLLMALLEVSGFILNQWILLRFLEVDLTESIRQLHVFGTYFGVMFSWATYRPGLEPRHEKEKSDTKMDLFSMIGTLFLWMFWPSFNSVLIEDTAQKISAVYSTYFSLAASTVAAFGLSVLTSKKGKINMVHVHNATVAGGVAVGTAVTVIQAPWVAMTIGVIAGLTSTLGLQYIKPRMASLFQVHDTCGVQYVHGIPGILGVFANITIQLATNWTSFILTAKEAVFQLTALSVTAALSLILGLGTGYLLKWNFWKAPHDKKCFDDQAYWKFPHLAMKL
The following text describes a protein:
Function:
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MGAWKVWTFFAIALVVAVKAYDEEAKCMSHDEDSQVKERQILHIVDSINKPISPDFRAPRGVIDEHKLRGLGTLKKREIFSLFDERNWDEASKVVRLLLDAKDFDDFIDVAEVIRLRVNEELFLYAFSVAVMHRGDTQGLQVPRIHDIFPDKFLKEDVIHRLLELSNRGEHYDRIPIIDATQISHNYLDPNSELEYFLEDLGLNSHHHHWHVIHPAIWVSELGNEKDRKGEFFYWMHHQMLARYEAERMSNGLARTRTFQNWNDPIDEGYAPHISIMKTGYTYAYRPPGYTLRDLPNLPKNKMVEWAKRVLYSIHSGIFHFSNGTDAHLDTEHGIDELGNIVESSLTSLNRDYYGNLHCYAHVIAGRIADPEGKYGEDNGVMYDVATSARDPLFYRWHKYIDNIFQEYKNTLPPYTTEELTPQNSEFRVQGISVVGETSARDTVHTYWQHSLLKVGQGFEFTKHTPAYVKVKHLQHESFTYVIDVENRGRTRTGFFRIFAAPKYNELGQKWHINDQRLIMVEMDKFIEKLYPGKNTIERHSEDSTVTMSSASIFSDISSEQSEDHCSCGWPDYLLVPKGNFEGFPMEVFVIVTDYEEDKVEGPDEGCACHDALTYCGGIDYHFPDKRAMGFPFDRPIKQRNFNAFKTKNMGKVTVDVKFTGETIAPEDFHNQH
The following text describes a protein:
Function:
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
Sequence:
MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSIGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
The following text describes a protein:
Function:
Acts as a histone H2A/H2B chaperone in nucleosome assembly.
Subcellular Localization:
Nucleus. Cytoplasm.
Domain:
The acidic domain is probably involved in the interaction with histones.
Sequence:
MAAAEQKGKKPRTDGAEAEPVDAALLQSIEKLQEIQDEIEKVNEEACDKVLELEQKYNEVRRPVYVRRNKIIKQIPDFWLTAFLSHPMLGELLTEDDQKIFKHLESIDVDDSEDIKSGYSITLTFSPNPYFEDTKLTKTYSFSDDEAVKVKATSIRWKKGMDIANDRAYTKKGDKRILIDESFFTWFNSEKNRSFAHGAMDEVADVIKEDLWPNPLKYFNNEFEEELELLDDDDEVSDDDDEEEDDEDQGEGEEDGEEN
The following text describes a protein:
Function:
Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Late endosome membrane. Membrane; Multi-pass membrane protein.
Sequence:
MDNPNLEAQNVISKCLKYFLFVFNLLFWAIGGVMFGVGMWSVTQKGSYSKLSSLSTDPGSVLIAVGLLIIIISFFGTVGALREQIILLEIYKWVIVVIVILQVLGGLLAFAFWPNVRKSVQNQISKGIVNYRDNLDLQNIIDGIQENFKCCGSSSINDWDANRYFKCGGPSPEECGVPHTCCVKKDGEVQHNFKIQSSRHERERCFYIIGCLDAVINWFRDHMYVVAAIAIAFALPEFAGIILTHIFVQQIKEQI
The following text describes a protein:
Function:
Probably binds lipids.
Subcellular Localization:
Secreted.
Sequence:
MIRAFLVVALASVAVFSAPIPEVPQNFDDIPAEYKGLIPAEVAEHLKAITAEEKAALKELAQNHKEYKTEEEFKAALKEKSPSLYEKAGKLEALLTAKFEKLDATAQALVKKIIAKGRELHQQYLAGDKPTLDSLKELAKGYIAEYKALSDDAKATITAEFPILTGFFQNEKIQAIVGQYVN
The following text describes a protein:
Function:
Required for gap junction formation, playing a role in anchoring the cytoskeletal component F-actin to the membrane of adjacent cells and thus facilitating the formation of gap junction channels in embryonic cells, muscle cells and neuronal cells. Plays a role in maintaining gap junction activity to promote pharyngeal muscle contraction.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell junction, gap junction. Note=Partially co-localizes with F-actin at gap junctions between EA and EP endodermal precursor cells in embryos.
Sequence:
MSGLCLVLLLSIFAVSQSSGECSDVSFSSVASKLDGLKRVTRLSVSGHISAYHVKVSISDDDFQLVRLSNGNPLVLYSTLSNTPSWTHVDFLATEVRIFPAFEQATEDVRGPLLILTICDYDTPITAFDDSSYTVEAHHAGLVSMYENDLCVVFRTYRSGVFFFSMADQGDVLIAQIIHGTVHVIFDFGSLTPSRISAGKALDDGRWHEMRWLHQFDSVQLSIDGVLLNQTAPTGLYRKLDLHSVVHIGGRPNDDFSQGIETTFTGCIARLQLNNADLLQLSPNEVHNQCQMPKPPSFTLHNSSRAVLPFTFLPFSFEFRIVPINGPLVTLFDAENGTLVDVVIDEESKLHLVSNITKFKQAANPAIDVADGAWHSFSLRIRGVRMEIDIDGYTVLWLEGHEVRRVSQRLSNFILSASGCYRSVTIDLTSVRVDGNVTRGECTFQEKCLPNPCENGGGCVQSALDDYVCNCKEGYKGKNCHTTDLPHSCEEWVFTKGNKQKAVQGRKVLIDIDGGGEMQPINVTCKTERDEIGIDGVSTILEHDLLRPMIVTGDNKPGAVRYSLTYGISTEQMDRLVEGFEACSQFMRYTCRGGARLMTQGDERSPSSWYSTRSDKHGLQWGEAPPYSRMCSCAINGSCLHNRMCNCDSGEDSTDEGVNPYSQLLPVTGLFLGGTTKSSSIEVEIGPLKCRNRATFDPVTFSNRNAKLSGAQTFNQRTFDVSLHVKFSHSQMSILSWHSTDDLHWFHLYVNDGKIVGEVVNGGESQQIVSEHRYDDGKFHAIYWEADSTGMFLKVDGQRKSVKTSFILPTVYMWIVGSRTEKGSTGFAGVIRNVHLCGVELALGQYARKETERGVAIGDDGYCRPDLCQNGGQCVDKYDGYVCDCSMTPFGGSDCTKEYGMMVPAGSSIQIPWQNPAHQAMCHRIAIQTTSRNTTILRSKALFADSTFNMTVDDNGNLQMMAYDGFFFHFKRQSKRHNLSDDIMHDISFCASKHHFNVSVDGMQVITIEGNWTFFESFNVWHFLDENFEGCVSRIQTGSAFPLKNPKTARLNYSGKIRFGTCPIEAVSRQQMYDFNPQPDLISSTIKTSTEDIKIFSVSQNKQDLVSKAIIGGGILALSLFILCMSSLICYMRSRPEGVYKTNETGENCSPSRSEEPLVHNTTSNNNNNPTYASNKEYFC
The following text describes a protein:
Function:
Essential component for signaling from various receptor tyrosine kinases such as Sevenless, TORSO and DER. Required for photoreceptor cell and wing development.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MDRTFYEGWLIKSPPTKRIWRARWRRRYFTLKQGEIPEQFCLEYYTDHNCRKLKGVIDLDQCEQVDCGLRLENRKQKFQYMFDIKTPKRTYYLAAETEADMRDWVNCICQVCHLHDTKQSNELPLGAVGADENRTQHTSSSGGLSNSTQNTTTTSLHSSAGTTAPQASVPNAGGSAQLRRPAVIEEQPMPSNAGNNNSDSVYVNTEYSNRETMLCDANFDQQELLSAAQQQPPPSPATALYLNHSALIQAQAAAAAAEQLQQQQQQAARLAVSANGVVRKLPEHLVLTQQTLAEAAAQQHSSVQASPALSTASGPYIPISECFSGSPRFLPGVPLPGADLAIPNNPTTPLNNLDPKFYDTPRSHNNIGLNLTNDQSYSPKITNLSLQQLANNNASKQRSDSDSESVFTDDDEWAHPLPLRENVDRSTRPSDSSIENESFVLTYSQRFSKMPEEGGAIVPPAEKSSKLAGAASLPEAGDQGTLDKLAKVLKNKNNLILDFKENEKIPRDLPQLSDTENTSPAIVARRNAHSAFIEESYDIPRSHQQPYYNVNQLLGERPVTSPHNSNPIAASTPNLMAADLGAVAAISAAANPGLMGEAQAVASSPTSARTLPRHCYTNAAPTKMEGNVFRYDFMEQADCPPVNRKLKPKVAGGLPVVEDKPPEEFPAKPPVGVDQLTNKLGAAQLQQPIGPPSVDRKCKPNAYKLGNSATMSPATRRSSGAPLSMVLPHETDVHSPAAANAFFHETRTLPRQQHRHHPNSPGSMSVQHQRTASAAAAMMSLTAAAAPKQQAAAQTEHKLQYFDLDVTNKPPLLNRSSMSVGNLYSQGGNGASGMRFAGVEAGGARAPVPSSVVYRSVDFVKTEAFKRIREERESSGNK
The following text describes a protein:
Function:
Catalyzes the condensation of 6-hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin-6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor in the biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT). To a lesser extent, is able to condense beta-RFA-P with another arylamine, 1-(4-aminophenyl)-1-deoxy-D-ribitol (APDR), to form 7,8-dihydropterin-6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol. Dephosphorylated beta-RFA-P is not a substrate.
Sequence:
MLMNIGKVDNIKIYTLAEDYAGYNSPFWSQHGLSFLIEVESNGIKKRILFDTATYAEPILFNMKLLNINPKSIDMIILSHNHFDHTGGLFGIMKEINKEIPIFAHPNIFKVSFATEPEFMLAGTLNKTLKEDIEKLGGRWVLSRDPIRLMPGIFTLGEIEDEEKINFEKKPTIGLYKLENGRVVLDNVEDEIGLAIVTEKGLIIVSGCSHPGIVSMVKKSIKISGINKVYAVIGGFHLIDADNERIVSTIKALKKLGVKKICTGHCTGFKAENMFMEEFKEDFERLHAGKIIKF
The following text describes a protein:
Function:
Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence:
MLEAINTSLFSPIGDDGMIGILLILNGLKVTLIVTFFAMLLGAVLGVGTTLMKMSSKWYIRFPAELYVGVIRGTPVVVQLVILYFIVLAALDVDKITAAIIAFGLNSGAYISEIIRAGIQAVDKGQTEAARSLGLSQAMTMKLIILPQAIKNILPALGNEFIVLLKETAVIGFIGGVDLMRAGEIIRSRTFEDSVPLFTCALIYLFLTYSFTFMLSKFEKRLKQSD
The following text describes a protein:
Function:
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the lumenal to the cytosolic leaflet of membranes and ensures the maintenance of asymmetric distribution of phospholipids.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPEALNENVSDTASNGPVAKTRAPPNTSFRQQRIKSWQPLLTPKIVLPLFFVLGIIFGPLGGGLLYASSIVQELVVDYTDCETLASYDEFSAVPSKKYTASFDQSGTIGFDKESTYWKLEKILDKDLDMDVNYCIIRFTVPSVLKAPIFIYYRLTNFFQNHRRYAKSVDEKQLQGVALTADEVKGGNCFPLEVNEDDKPYYPCGLIANSLFNDTFSSLRLLDDNSVYTFSTKNIAWASDKRRFLKTNYSPDDVAPPPNWVLRYPDGYTESNMPDLSTMENLQVWMRTAGLPTFSKLAMRNDNDDIFPGTYEIKIGLFFPVKSFDGTKSLVLTTRSVLGGKNPFLGIAYIVVSAVCVVLGTVFTLRHFIRPRKLADHRYLNWDSEENNLAPHLSDRP
The following text describes a protein:
Function:
Essential for survival of retinal photoreceptor cells.
Sequence:
MAACAGGPGSWSENILKYFLRNNQITAEDGAEILWSHAANHKSQMNEALKSAAHMIEADVLLPSDGSEHGQPIMAHPPETSSDNTLQEWLAEVVKSNKGIKLDFKSLAAVRASMLFLDNMKQHLQRPVWINADILPGPNGSSKVVDAKAFLDTVTSFFPDVTFSLGWTTGWHPEKVNEGYSWSMVKEMDYICSELTQPVTFPVRAALVRQSCPQLLWLLTKSNRYSLTVWTGKDDIYSTEDLLYIRDYFNKTQVFYDISEPQNHEFKQAIGIRGHSLRI
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular Localization:
Nucleus.
Sequence:
MSVLIVTSVGDIEVDLHTDELPITTKNFLKLCKIKYYNGCLFHKVERDFLAHTGDPTGIGTGGDSVYKILHGDQDRFFDDEFRPDLRHSKAGTVAMAGGSQFYFTLRDGVDGLDGKHTVPFMDIRIKHTYVLDDPFDDPPQLAELIPGDSPIGKPRAEIAEDRLDVPSDDALANIPGVEQADNVLYISKLNPITEDEDLRTIFSRFGTMTSAEIIRDCKTGDSLCYAFIEFEAKEDCERAYFKMEDSLIHDRRIQVDFAQNVSKLWGRFRQSTRNADKDGRLKCGAPDHLARDCDQGVEEENKGTNYVLEDQNTHRGGNNRRSYDLVFDDDGTY
The following text describes a protein:
Function:
Catalyzes the oxidative cleavage at the 15,15'-double bond of carotenoids and the simultaneous all-trans to 11-cis isomerization of one cleavage product. Carotenoids like 11-cis retinal can promote visual pigment biogenesis in the dark. Essential for the biosynthesis of the 3-hydroxyretinal chromophore of rhodopsin from zeaxanthin and for proper photoreceptor development. Also essential for larval light perception.
Sequence:
MAAGVFKSFMRDFFAVKYDEQRNDPQAERLDGNGRLYPNCSSDVWLRSCEREIVDPIEGHHSGHIPKWICGSLLRNGPGSWKVGDMTFGHLFDCSALLHRFAIRNGRVTYQNRFVDTETLRKNRSAQRIVVTEFGTAAVPDPCHSIFDRFAAIFRPDSGTDNSMISIYPFGDQYYTFTETPFMHRINPCTLATEARICTTDFVGVVNHTSHPHVLPSGTVYNLGTTMTRSGPAYTILSFPHGEQMFEDAHVVATLPCRWKLHPGYMHTFGLTDHYFVIVEQPLSVSLTEYIKAQLGGQNLSACLKWFEDRPTLFHLIDRVSGKLVQTYESEAFFYLHIINCFERDGHVVVDICSYRNPEMINCMYLEAIANMQTNPNYATLFRGRPLRFVLPLGTIPPASIAKRGLVKSFSLAGLSAPQVSRTMKHSVSQYADITYMPTNGKQATAGEESPKRDAKRGRYEEENLVNLVTMEGSQAEAFQGTNGIQLRPEMLCDWGCETPRIYYERYMGKNYRYFYAISSDVDAVNPGTLIKVDVWNKSCLTWCEENVYPSEPIFVPSPDPKSEDDGVILASMVLGGLNDRYVGLIVLCAKTMTELGRCDFHTNGPVPKCLHGWFAPNAI