lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition and for maintenance of filamentous growth. Through binding to CDC28 controls the phosphorylation of CDC11 and SEC2 upon induction of filamentous growth.
Sequence:
MTSLQQQRVKYGPPHHIKRRPYHPILESLEFQTNQHLIQEYSLDIVNTLSQLESLTLVNPAMIDLQPEIQWFMRPFLLDFLIELHSSFKLQPTTLFLCLNIIDRYCAKRIVFKRHYQLVGCTALWIASKYEDKKSRVPTLKELTIMCRNAYDEEMFVQMEMHILSTLDWSIGHPTLEDCLQLAIDSNNLSNNTTNDIENKSVRPNRKSSISSAVTAVARFLCELSLYDKYFLSVPPSLIAITANLLSCSMLQIPHASITLKNLIEQEIINPQQKKQKKALSSNSSRTTTASYTHQNQSDVRHSSFDEDIDLDSGDEEDDDEDYIDEFYETNNYDDTNATTFDESISKSTTVNDENQPPQIHTPFLSGLDEDSILSIKKICLMLIIQLSKVTEVLSKKYENLGVIQVINNFHSNYKFIIQSIYENQELLLNTINDSTNNNEIDYKLIQSSEILLQFPKFDEYLTEDEDENVSTDDEANSQPQGYDGSGSDGNNQLFTPKSPNAFSSNSSLTLNNHPQSMVPVTPPSATSQYSLFSNKNNRTHESTSGLNSTCNTPTHISISSFAPPQPPPGSILKPKLTSINSTNSLKIKKLTSNSNSSNINIHHGHHNTKQEKRYSHISIGSNSSSKYDGFSPIKSISTNGSLITNNGSLITNNGSFTNIVNNTNSSSPLMNQQQQQQVTQSSLYQHHHQYHQ
The following text describes a protein:
Function:
Cleaves the N-terminal amino acid of tripeptides.
Subcellular Localization:
Cytoplasm.
Sequence:
MNLKQELIERFTRYVKIDTQSNEESHTVPTTPGQIEFGKLLVEELKEIGLTEVTMDDNGYVMATLPANTDKDVPVIGFLAHLDTATDFTGKNVKPQIHENFDGNAITLNEELNVVLTPEQFPELPSYKGHTIITTDGTTLLGADDKAGLTEIMVAMNHLIHNPQIKHGKIRVAFTPDEEIGRGPAHFDVEAFGASFAYTMDGGPLGGLEYESFNAAGAKLTFNGTNTHPGTAKNKMRNATKLAMEFNGYLPVEDAPEYTEGYEGFYHLLSLNGDVEQSKAYYIIRDFDRENFEARKNNVKNIVKTMQEKYGEDAVVLEMNDQYYNMLEKIEPVREIVDIAYEAMKSLDIEPNIHPIRGGTDGSQLSYMGLPTPNIFTGGENYHGKFEYVSVDTMEKAVQVIVEIARRFEEQA
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSTLTKIVLLSILVRLISFLLLLLTNPLLISSFDHSAQSNTTIIINSSHSSDGTPSTSSPPTPEQQTATASILSTLILYQLTLKLSSHSTSYSALVGLLHLFSPSPSTQVVPYTEPFYALFSFAAIYLIEAKHHWPAAILAGIATSFRPIGVIQCLLWIPQWTNHLKQLINNPKQSSALIRFISTSLKTLLLALITSAPFIYDQYSAYKHYCYQSSSPRPWCSNRIPSIYTFVQSHYWNNGFLNYWTFNQLPLFIISFPIYWASFAGIWNYYGSTRFTTPKTHQSKPDEARSIIKQSGYRPFLDPRLQIHILIQLLLTSLLLFNSHVQIILRQIATIPAFWWGLADGISRHWNQQQSSNQHNSHRIARSYWAWWFPWIVVWAPISLVLWAGFYPPA
The following text describes a protein:
Function:
Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.
Subcellular Localization:
Mitochondrion.
Sequence:
MYRRSLILRHSNLPSRCINIIRNYSNSQPSDNKYKDYDFIIEENRSPQDIVKNYLSPEQIEGHIESEGVLPPQEMSPFRNPDGTFIKGKNSAEARLDDRTLEGKIDHSITELPHRIAKTIQNNIIKLSIPARLRTRVAHIYQNLQKNQIQQAPSTPLDCNAHIAALFLQDYSHAKQVLSELQRRVGKDKFKPQRILDIGYGPATGIVALNEIMGNKWVPEEKEAYIVGRKNNEMKKRAKIILSRQLNENYSGKELNLDENVVQKDQRPVQEEEDYVEEEEENSSEENDYVGHIDVKRLHIRTKLRDTLPVTKNYDLIIIHSSLLSKEFNFPKDVDDNIHMVLPLLAPGGHLVLIERGNSVGFETIARARQIMIRPESYPQELGKIPRPYIKGSKGKPQKMKKEDQFITQEDVEFEKELLAKLDYQEALEKARELGEDFEKELNEKFGAVSEEELKFENEDSEELEVFDVNTPREDMYDKVDYHLSVIAPCPHHRKCPLQLGDPKYYKIPDHRHRLNFCSFSKIVARPPYVIELKKGKKLAIRWDKSAEDGIGSISRNAVKRLAGSGRPGGRDTEVGSYSYLIVERSANDLETIKKIEDLRSYSDNVIDENDITNWPRIIATPNKLKRNVKLTVCSTEGNVETWQVPKSLGKQTYHDARKSQLGDSWALGRKTRTIKNQIPEAVKDKLDVLYKTSKKTFKKEQQRKRWKKKVGTSVEEFEDGFFATEVMASQLESSKKYKQQARQAQFEEDPSKFDGN
The following text describes a protein:
Function:
Represses the expression of the STM4065-STM4067 operon.
Sequence:
MQVDKTSFTPLYKQLFFIICQQIQNGSLPLGSQLPTQKEIARSYNVSLIVVKQAWSELINAGIISSQRGSGSVVCSVPEGVSYGHTFRGITRDLQDASVAIENRILEIAPRRARDAQADGLSLPAQHHYLYISRIRCLNNRPFNHEKIYLDLSFFPGLELTPQALEHTSLYSLLNVTSDSAIEKVEAILPSADLCEKLQIAANKPLLSVARQTFQAGKDSPFEYCRYYVLSEYFGEIHYH
The following text describes a protein:
Function:
Transcriptional coactivator or corepressor of the p300/CBP-mediated transcription complex. May be involved in sex determination, early gonad development, left-right patterning during embryogenesis and differentiation of the adrenal cortex.
Subcellular Localization:
Nucleus.
Sequence:
MQMLLMSMADPMMMPVMHGGHPNYRVGMNPMQAPPCHQTRTMPMHSGHMMQYGFSNTDENMRARMGMQQHVPAHMMYPTQSQSYMGSTQQLMATMHLQRLNTQYQGQPLMSNPGLAQTHQMYRTASAQHQHMPTLNVTDTDLVDEDVLTSLALELGLDRIEELPELYLGHNEVDFILDFVCKQQSSSVTC
The following text describes a protein:
Function:
Dual chitinase/transglycosylase that plays a role in cell wall architecture. Chitinase and transglycosylase activities are coupled (By similarity). Required for the polysaccharide cross-linking at the septa and the cell wall (By similarity). More specifically, transfers chitin to 1,6-beta-glucan in the cell wall (By similarity). Plays an important role in fungal pathogenesis via its functions in cell wall assembly and regeneration, filamentation, and adherence to host cells.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Sequence:
MYKQILTFLILFLRYILSEFPDDPYEDDDTSDDNNSDYEGQKCNPYRDKACLVNDEALGKKIFESFAEGTKYFTITSSTRGVRFGSEGLALTIQDEFDNPALVSSFYIMYGKVEAEIKGAAGKGIISSFYLQSDDLDEIDVVEIFGSDPYEFQTNFFIKGNTTTYDRGRYHEMHPSPLSEFHKYGIEWSPDLITWYLDDKPVRMLGRRNKHGLPCSPMFLKFSLWSVEDDDEGTIAWAGGAASFSEGPFTMHIKNLKVQDYSKALTYSYGNLRDGNWLDLRADGGYLYEGHKYCLPPKMLDKLKPTPKQETDDDQVLTSSKSQRVATTISEDKNTVSYYPPSATNSHTTWDRLSEWETEQDETGTDDTENSDNEEEESITAIPISKSRKGSTRRLDISTQLPPLSQNESKIAEIKNITTTKHIHNTTTSLQISKIKSKKVGVTTTIYSSSTPQSTSKSRMPYNIFFNYPGKENSRFKSGVSSILATSFSSVVIAEILVIVVLLL
The following text describes a protein:
Function:
Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTLILAIIPVLLLIVLMAFFKMSGDKSSIISLIVTMLIALFGFAFSVDNLFYSFLYGALKAVSPILIIILMAIFSYNVLLKTEKMEIIKQQFASISTDKSIQVLLLTWGFGGLLEAMAGFGTAVAIPAAILISLGFKPIFSATVSLIANSVATAFGAIGTPVLVLAKETNLDVLQLSTNVVLQLSVLMFLIPLVLLFLTNPKLKALPKNIFLALLVGGVSLVGQYLAARYMGAESPAIIGSILSIIVIVLYGKLTASKEEKARKSTLKTKDILNAWSIYLLILFLIILTSPLFPSLRSTLENNWVTRISLPVNATTVNYTISWLTHAGVLLFLGTFIGGLIQGAKVKELFIVLWNTVKQLKKTFITVICLVGLSTIMDTSGMIAVIATALATATGSLYPLFAPVIGCLGTFITGSDTSSNILFGKLQASVAGQIHVSPDWLSAANTVGATGGKIISPQSIAIATSAGNQQGKEGEILKAAIPYALAYVVITGIIVYIFS
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTTVLVTTPTLLKYSYKLTGVVPFPFTTSKPTKISQVVSHIWPIFFCLYFISIYLFYTSVNNETKIFSYINFLVYHWNVLYMVVYVVMLHKRSTKVKKLLTEISKIQLITNNNSKSNERYVRIIQIVTLVCLLVTFLLRNIPLTYTIYFMYPCTISTFDNLFINDVLNEFCNKFKTINRKFENIVAKFGTSESDFNIEIIQKLSHHHYNLVSLVLEMIKQFEITLIVAITQTFIVMVDSVYTVTFLIFNKRVLTFHFGCNLFFVHYAICWLFNLIRKFSETQEETNKAGSYVHCIWNKYSLRGNIEKKMRYLELVSLRLLNTKVNFTASGCFNLDWTLLQTIIAGVTTYWVILVQFPN
The following text describes a protein:
Function:
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MKKQLFWAPQNEIPSTLWTANERSWLTHPGSLTQRLRKTTDGQIQHHLLREVFDAPVDEETQLLGISQPELALIREIEWRYFESLWVAGRVVIPKKTLEREGSPLNHIGERSLGDILFANAKFTRGDLEFRQITADHPYYFYVKEIANGSCIWARRSLFYFERDPLLVSEIFSPALFLESSVSND
The following text describes a protein:
Function:
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSEVETSTEEQQEMQDTVVSPEKAEEIKLKARYPHLGARPGGSDLLRKRLQKGQQKYFDSGDYNMAKAKMKNKQLPAAAAEKTEITGDHIPTPQDLPQRKQSLEASKLAF
The following text describes a protein:
Function:
Involved in the biosynthesis of sterol glucoside. Can use different sterols such as cholesterol, sitosterol, and ergosterol as sugar acceptors.
Sequence:
MDEFTSDSLTTSRLLRQISHSDSLSSVGSSSNRSNSNYENKINNGIINDFDSTNANDGISNNSNNSNNNNNSSSILKIHQSPQSILSTEQQHQIQQYQQYHQQQIYESGYVPPHVYIFDPDYKSNNDEEDKEKRSLIELNKSTDLSNIKTTTTTTTTTTPPPLMIPENEEENKQLRQEILNELSKSESFTKIKEPGEIYGFCECSLLYNHLTCANLVITSNYLIFLPQQQVDSDYVLENYLYKKGDFFWKKYWFVLTPDSISWYKSSILKETHYPNGTILLSKIVTVDKLDPEETGKPFCLQIMTNTSIHLIQLDTEPQLEHWYHEINRMQKNLNVTIPIGDIVSITMESNAALFFDSLCLTLKKGENCLVTPSSSSNEVYSLLIKLWNRNRGVTVVEPEKQQRLLEFQKTFKLSQGVNLLIETPCVFYQDEEFSYEGVLYATTEGTLYFSSLDSVLIIPESDIYAITIDRKSDNRDALKVYTTDYDVLFFDSIDDIETFFNVISTSLARSNPKIFFSTVGQIPPIDEPKHDEKEHKSTYQTISSGIRSWKIPIPSLPNFSIPIPKSIPIPLFRSKSSSHLDPQNSQQQQQQQQQSSSLQLDDNNNNIVIPHTSNPTTIIPSTSSSSAIPPPPSSTSSTSSTTHEKTIIIQKNSSINSTFHDIFPLLPLDETVIMFQNCSLYYYSYDSNVEGIVYITKSYIAFNPSPLDKQQQQQQQQQQQQPNSSSITSTTYDRDLDTDSDTDSESDFDYPKQSQHDNSVVMVNNNQYKVKEVLMKKALIPIEDIVSVTKERFLLFFNQCVKIITLDHKWIFGSLNNINSFYNLILETWKQIPKTLLDSSSSSSSSSSSSLLSSSPNNNNSDLNINGNSEGSIFTPLESIKIKNKLGLPADEVLITWFNCTNFKGAQLKYGFLYISNNNICFRSKFGFQKRTIVIPLSQVIEIKKYSAFIPNGIKITTASHHEFQFASFIHRNRVYQILYETWLKANNKKSNSSNSLSSSPTITSPLAISPSIASPSITPPSSTPPSSTTPSSTTPTITSPTIHSTLPSTVVYNDIQEIIDGENNSNNNNNNNNTNNTNKSNSFIGNVEEDVDKIKRSIKSLPILKIHSAQQQQQQQPKTTTTTTSTTTTNLISPRLLTPLTITQSPGFSSLVNSPILPVKPLRITILTIGSRGDIQPFIALSLGLKEYGHNVTLATHELYRDLISKEFGLNYQPLGGDPRELMDLCVRNGIFTPKFIKEALSRFRSFIDDLLLTCWKAVQNSNTQVLIATPGCFAGPHIGEVLQIPFFNAFTMPFTRTRTYPNPFAPFASHQMGGVFNLATHVMMEKVLWQPISGQINQWRTETLKIPPWNSSVSINETYRMPYLYCFSKYLVPKPPDWSGEIAITGYWTLKNQANSDSPPDDLIQFLNEESSTENDDIPIYIGFGSIVIDNPTALSLLLIEAIKLSGKRAIISQGWGGLSIDEHNNNNNNNNNNNNGENSDSNKSSLQSNRIYLLKKPVDHSWLFEKVSLVISHGGAGTVAASLLAAKPTIVVPFFGDQFFWGERIKQTGIGTSIPFDILTAKSLSSHIISILNEPSVRAKVNKMSHLLKREDGVKTAIDFIHRYLPFSFIPPREIPFSSAPNSCMGCKQPFTLLHVMKARVHCHCCGKIFCESCTSHKCPIKKYRINTPVRVCDKCFNDLQSNPSSNSFILND
The following text describes a protein:
Function:
Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase. Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MLLQSAAGWSLALVALVALTSLRAVNAEEAVAQQVNAEEFETLRQQTALFVKFYAPWCGHCKQLAPTWDKLNGLIPDDLAVNVVKVDCTQHGSNKPLIARVSSKDDLATRLVAAKTTPFVLFVQDKAPATALERAAGDMLPNVACAVATPAVVADAGLSLTPGIYLCKDEETLTYTGEPENLADWALLHRFPRVFEFNSQNARGFYGNKNPPSVAVLLVEDADSTGAAQALKLANVIEDQQFAFMQPKMIPFLVNKIWQADTNQLPILVVHDQANMVFFMYDGDVADTAAVQAFLADVKAGKVEGSSINSSSRFLEKQLQSIMAGFVYLRDEQPILMGVTLFCAMCAMIVAFQALFREDKAQAKVEQAAKSAQSKKAD
The following text describes a protein:
Function:
A putative methylase that may protect DNA from cleavage by an unknown endonuclease.
Sequence:
MNVIDLFSGCGGFSKGFLDENFRILGAIENFKPVVKTYLYNIKAPVWMDDIKRIPPKAFDEFIKNEKVDVIIGSPPCEPFTKANKLIKDNPLDRLYKDKVGRLVLYYIDYVNYFTQRNDDLIFVMENVPQIKEIKDELKKLFGDIGHKVYFNILRAEDYGNPSKRARMFISNIKLKPKKVDKLVVVEEALKDIPKDAKNHEIKKLSKEKVEMISKLKWGEALYRYRGKKKLMFNWYKLHPKKLAPTVKGRSRFIHPYEDRLLTVREQARLMSYPDDFVFFGGRDVQYNQIGESVPPILGRAIAKEIKKQL
The following text describes a protein:
Function:
Supercoils relaxed DNA in an ATP-dependent manner. A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state, also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes. At comparable concentrations has a stronger decatenation activity than E.coli, which is inhibited by ciprofloxacin and novobiocin. Cleaves dsDNA at the sequence 5'-AT/GGCC-3', leaving a 4 base overhang. Relaxes negatively supercoiled DNA in an ATP-independent manner; Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
Miscellaneous:
MISCELLANEOUS: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
Subcellular Localization:
Cytoplasm.
Sequence:
MAAQKNNAPKEYGADSITILEGLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGFATRVDVKIHADGSVEVRDDGRGIPVEMHATGMPTIDVVMTQLHAGGKFDGETYAVSGGLHGVGVSVVNALSTRLEATVLRDGYEWFQYYDRSVPGKLKQGGETKETGTTIRFWADPEIFETTDYNFETVARRLQEMAFLNKGLTIELTDERVTAEEVVDDVVKDTAEAPKTADEKAAEATGPSKVKHRVFHYPGGLVDYVKHINRTKTPIQQSIIDFDGKGPGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRAALTSVVNRYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVAEPQFEGQTKTKLGNTEVKSFVQKICNEQLQHWFEANPAEAKTVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDPSKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQSIITALGTGIHDEFDISKLRYHKIVLMADADVDGQHISTLLLTLLFRFMKPLVENGHIFLAQPPLYKLKWQRSEPEFAYSDRERDGLLEAGRAAGKKINVDDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVEARRSFITRNAKDVRFLDV
The following text describes a protein:
Function:
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
AFTRCPALSTIQGNEISHLFLTADSQEVLSVIPAQRNLQEKGKSHLKHPEDHGKPLEDFPSLSRAPLSGNLSPIPPGSSQPLLAFGNGSPIRSSVSPTFRGRKRLSSEQNVPYDVKRQRFHSPHHESTAVHPTVPLRDERRYSIPGAITPSLFPTHYIPDLVRCVPPLQETSFLEPREITLPVAKDKLSQQVLDLFQECQQQACDLKKKELCRTELQREIQRIYPQSRLFLVGSSLNGFGTRSSDGDLCLVVTEEPVNQKTEARYILSLVQNHFSTRLSSYIERPQLIRAKVPIVKFRDKVSCVEFDLNVNNVVGIRNTFLLRTYAYLENRVRPLVLVVKKWASHHDINDASRGTLNSYSLVLMVLHYLQTLPEPVLPSLQKKYPNSFSPSMQLHLVHQASCTIPPYLSKNGATLGDLLLGFLKYYATEFDWNSQMISVREAKAIPRPNGIEWRNKFICVEEPFDGTNTARAVHEKQKFDMIKDEFLKSWHRLHNVRDLNSILPLRATIQKR
The following text describes a protein:
Function:
Putative odorant or sperm cell receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MFSSRDELTARVSNVTEFILLGLTQNPELQKLLFGVLLTTYLITLAGNLLISVTIFISPALASPMYFFLSYLSLIDVFYSSSIAPKMIFDLISGTNTVSFKGCMTQLFAEHFFAGSEIIMLIVMAYDRYVAICKPLHYMTIMSPPVRAFLVGMAGALGFIHGGIQVLFMVQLPFCGPNVIDHFMCDLIPLLELACTDTHTLGPLIAANSGPLCLVIFCMLVASYGAILRSLRTHSSEGRRKALSTCASHVTVVILFFVPCSFLYLRPMTSFPTDKVVTVFCTIVTPMLNPLIYTLRNAEVKDVFKKLWGQIMKTGGK
The following text describes a protein:
Function:
Acts as an actin nucleation factor and promotes assembly of actin filaments together with spir. May play a role in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to membranes via its interaction with spir.
Sequence:
MALQLGKKLAQVLGSGAGSPLTPGTMEPCAAGSGSPLANGELFNVSKAKKVELQNLSSRFTAAVTQTPPGVTSSTPNESGVTGPAGPLGATTSSPSLETQSTVIISFKSSQTPVQSQTNSAASENVEDDTAPLPLPPPPPGFGTPTTPLLSSNVLKKVASFTVEKSSAGNNSSNPPNLCPTSDETTLLATPCSSSLTVATLPPEIAVGAAAGGVAGGAGSRRGSSYVPEKLSFAAYEKFEGQMLIKWLISTMQSNPKSSSGDANQELFNTLALQFCNNLKYVGVLKQISNEHLDCGFSPYEMYQWTHTEQPTTSLPLTPGKLDKVAAWPFSSTPSGIRALESASLASLGAGGVAGSLATIATASTASSDNQKTLQQILKKRLLNCTTLAEVHAVVNELLSSVDEPPRRPSKRCVNLTELLNASEATVYEYNKTGAEGCVKSFTDAETQTESEDCEGTCKCGQSSTKVSDNESAKEDGEKPHAVAPPPPPPPPPLHAFVAPPPPPPPPPPPPPPLANYGAPPPPPPPPPGSGSAPPPPPPAPIEGGGGIPPPPPPMSASPSKTTISPAPLPDPAEGNWFHRTNTMRKSAVNPPKPMRPLYWTRIVTSAPPAPRPPSVANSTDSTENSGSSPDEPPAANGADAPPTAPPATKEIWTEIEETPLDNIDEFTELFSRQAIAPVSKPKELKVKRAKSIKVLDPERSRNVGIIWRSLHVPSSEIEHAIYHIDTSVVSLEALQHMSNIQATEDELQRIKEAAGGDIPLDHPEQFLLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQADGFNLDILGKLKDVKSKESHTTLLHFIVRTYIAQRRKEGVHPLEIRLPIPEPADVERAAQMDFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEIMEPFKSKMEEFVEGADKSMAKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFKDIWKKEITSLLNELMKKSKQAQIESRRNVSTKVEKSGRISLKERMLMRRSKN
The following text describes a protein:
Function:
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction (By similarity).
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Sequence:
MGFQPPAALLLRLFLLQGILRLLWGDLAFIPPFIRMSGPAVSASLVGDTEGVTVSLAVLQDEAGILPIPTCGVLNNETEDWSVTVIPGAKVLEVTVRWKRGLDWCSSNETDSFSESPCILQTLLVSASHNSSCSAHLLIQVEIYANSSLTHNASENVTVIPNQVYQPLGPCPCNLTAGACDVRCCCDQECSSNLTTLFRRSCFTGVFGGDVNPPFDQLCSAGTTTRGVPDWFPFLCVQSPLANTPFLGYFYHGAVSPKQDSSFEVYVDTDAKDFADFGYKQGDPIMTVKKAYFTIPQVSLAGQCMQNAPVAFLHNFDVKCVTNLELYQERDGIINAKIKNVALGGIVTPKVIYEEATDLDKFITNTETPLNNGSTPRIVNVEEHYIFKWNNNTISEINVKIFRAEINAHQKGIMTQRFVVKFLSYNSGNEEELSGNPGYQLGKPVRALNINRMNNVTTLHLWQSAGRGLCTSATFKPILFGENVLSGCLLEVGINENCTQLRENAVERLDSLIQATHVAMRGNSDYADLSDGWLEIIRVDAPDPGADPLASSVNGMCLDIPAHLSIRILISDAGAVEGITQQEILGVETRFSSVNWQYQCGLTCEHKADLLPISASVQFIKIPAQLPHPLTRFQINYTEYDCNRNEVCWPQLLYPWTQYYQGELHSQCVAKGLLLLLFLTLALFLSNPWTRICKAYS
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that acts as a negative regulator of NOD2 signaling by mediating ubiquitination and degradation of RIPK2. Also catalyzes ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum. Could have a role in spermatogenesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MGRALARGAVQVSLILCALLAPSRAVVRVVLTGNGSAVDFAGSQALFGAPLAPQGVRGYLMEAKPANACHPIEGPPRPGNGSLGAIVLIRRYDCTFDLKVLHAQRAGFEAAIVHNVHSDELVLMAHVYEDVRHRITIPSVFVGEAASQDLRVLVRCDKLAHVLLLPDYLPCPEPDCHPLLAASWVLGRALALLASAAFVLRRLWRWLWARWHAERTVETQACQKAQVCTFTRHSNLCAVCLDEYEEGDRLKILPCAHTYHCKCIDLWFSRGARRACPVCKQSVAGTEDGSDSTADSFGDEDPSLPGRRPPVWAIQARLRSRRLELLAQASPARHHRGATSLGTVEAEASSEGSPGAP
The following text describes a protein:
Function:
Polymerizer-type lectin that may facilitate the correct polymerization and activation of BGLU23/PYK10 upon tissue damage.
Sequence:
MAKIYRKLTGYGGEGGREWDDDVYEGVRKVYVGQDINRITYVKFEYVKEDGQVVTTEYGKIIQQPKEFVLQYPDEHIIAVEGNYRGVALCATEVITNLVFKTSKGRKSPLFGPNLLGITTGTKFVIEDGGKKIVGFHGRSGNALDALGVYFVHGSLTTSPPVYKLDAQGGTDGRVWDDGSYDGVKSLRIGQDNSRITYLEFEYEKGGKLETCRHGVKQERSLKFELNPDEYIKSVEATYDKPDIFRNVVITSLTFETSKGRTSFSGYKGGKKFKLEQKGRRLVGFHGKEGSAIDALGAYFAPIPTPTPIIPAKKLPAIGGSGGVAWDDGVYDGVRKILVGQGNDGVAFVKFEYNKGKDLVSGDDHGKMTLLGTEEFVLEDGEYLTAIDGYYDKIFGVETPMIICLQFKTNKRESTPFGMDSGEKFSLGEKGHKIVGFHGQASDVVHSIGVTVVPITNTK
The following text describes a protein:
Function:
Required for the expression of gene products mediating border cell migration. Among the DNA sequences that this protein binds with high affinity is a conserved site within the promoter of its gene.
Subcellular Localization:
Nucleus.
Sequence:
MLNMESPQMYADAVQTLAQLDLKKEPPLQQATIGQITLTAMSTAQQQQQQQQQQQQQQQQQQQQQQQQPQQQTTDANNNTSQDAALLVKQHAMHQMQQVAALGSNNNLLQKQMLQQYSTQTDLDELTTQEITLDLQHLIDDQFRDTETLGIFSDMVTSPGGLSATLPPSGMVSAAAKVLQQQTLRNQHGYGGRGGGGGAGGALAYMPQPVHATYNNSSDENSSVGSDSSTIKEEPIDPEYRRHLQEAASQQAAFMGNGAGLYNGYGSGANGLTGGGNPLNGGNTTPSSNGSNGSTGSSNGSQFTNLTTANVLAHHNLPHLAAAAGAHNLLKQHSKLHAQQQHQQHQQQQQHRKHSNKHVDKGTDEYRRRRERNNIAVRKSREKAKVRSREVEERVKSLLKEKDALIRQLGEMTNELQLHKQIYMQLMNHANPEVSRVCRSFLNTNEHSL
The following text describes a protein:
Function:
Lignin degradation and detoxification of lignin-derived products.
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MEYSWRKVLLLEILGFLLFDGLLCMAAGAVYRHDWVLTEKNYTRLCYTKPVLTVNGLFPGPELHVHKGDTVIINVVNQATYNITLHWHGLKQPRNPWSDGPEYVTQCPIQPGANFTYQLIFSDEEGTIWWHAHSDWSRATVHGAIMIYPKHGTSYPFKKPHGEVPIILGNWYNGDVMQIIEDALQSGGEPNQSNAHTINGLPGDLYKETYSCANPGTFEMIVKKGRRYLLRIINAGMNEEMFFKVAQHNLTVVGSDGAYIKPITTETIMIAPGQTMDAILTADQTPARYYMAVTVYASGNVPYDNTTGTAILTYKNYKKSSSPVMPSLPAHNDTDTADSFTKQFRSLESAEQVPKDYDLRIYTTITVSTLPCESGSTCLGPNGTRLSSSLNNQSFVNPSIDILEAYYKSIAEVYTTDFPSEPPHPFNYTGDDLPSSLLTATQGTKVTVLDYNTTVEVVFQGTNLNGPENHPMHLHGYSFYLLGSGYGNFNNVTDPASYNLVDPPLINTVSVPKNGWAAVRFRADNPGVWFMHCHFERHASWGMNTAFIVKNGSSVNESLIPPPPMPPCSNFNYEPNGTLVLAQLLTFQNHKMTSPTTDQLHLIIRFCMLEIQIQTFINYLYIHKSTKSLVQESGTNKDFLSTNKMWPRRKQLLGLHQFLLGFLLLNGLLSCRASVRHRFVVKEAQYTRLCSTKNILTVNGKFPGPTIHVHKGETVIVDVYNKGNYNITLHWHGVRQPRNPWSDGPEYVTQCPIQAGGKFCYKIIFSKEEGTLWWHAHNDWNRATVHGAIVIYPKHGTTYHFPKPSSEQLIILGEWWKADVMEVLQEASKTGGQPNASDALTINGQPGDLFPCSAPETFRILVEQGKTYLLRVISAAMNDILFFSIAQHSLTVVGTDASYTKPLTRDYILISPGQTFDVLLQADQPPNQYYIAARTYSTGQGVSFDNTTTTATIQYSSGNYNASGPPPSLPVLPYYNDTNAAVNFTGALRSLANEEHQIDVPLAVDTRIVTTISINTLPCSNTSCIGPNGTRLSASMNNISFVNPSIDILEAYYNRITRVYGTNFPSRPPFLFNFTADSLPQNLRTPKLGTEVKVLDFNSTVELVFQGTNLVAGEDHPMHLHGYSFYMVGWGFGNFDKHMDPKRYNLVDPSEHNTILVPKNGWAAIRFRADNPGVWFMHCHLDRHLIWGMNTVFIVRNGAQEEERMLRPPPDMPPC
The following text describes a protein:
Function:
Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
Miscellaneous:
MISCELLANEOUS: The reaction takes place in three steps, mediated by a phosphocarrier histidine residue located on the surface of the central domain. The two first partial reactions are catalyzed at an active site located on the N-terminal domain, and the third partial reaction is catalyzed at an active site located on the C-terminal domain. For catalytic turnover, the central domain swivels from the concave surface of the N-terminal domain to that of the C-terminal domain (By similarity).
Domain:
The N-terminal domain contains the ATP/Pi binding site, the central domain the pyrophosphate/phosphate carrier histidine, and the C-terminal domain the pyruvate binding site.
Sequence:
MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVSVPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQPELENAIREAYAQLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAVKHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQVVFITSAWGLGEMVVQGAVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHGKQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQARPETVRSRGQVMERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVLVTDMTDPDWEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGENVTVSCAEGDTGYVYAELLEFSVKSSSVETMPDLPLKVMMNVGNPDRAFDFACLPNEGVGLARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLTEGIATLGAAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFALECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIPSNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRAAKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK
The following text describes a protein:
Function:
RNA-binding protein that binds to the consensus sequence 5'-UGUGCCAUA-3' in mRNA 3'-UTRs. Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. By binding to the 3'-UTR, represses phosphatase lip-1 expression in the distal part of the germline mitotic zone. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform b 3'-UTR. Suppresses germline tumor formation by preventing the dedifferentiation of secondary spermatocytes. C-terminal disordered region probably auto-inhibits RNA binding; auto-inhibition may be reversed by interaction with lst-1.
Miscellaneous:
MISCELLANEOUS: Fbf-1 and fbf-2 are >90% identical on both nucleotide and protein sequence level. Experimental approaches often do not distinguish between the two genes, which are collectively referred to as fbf and are considered to be functionally redundant.
Subcellular Localization:
Cytoplasm. Cytoplasmic granule. Note=Recruited to P granules by dlc-1.
Sequence:
MDQSKMRRTNQFRKTSQKPPSTGIDSYPTPAQSPMAQHETPMWDFNSLNPYFSMLNMNDGINYARHQQNHIVTSRPPTPLTDLMSLRSFQSFPNVFMPVSRSRTSSFIQSDTDSSRLESDDFSQNVRCFSADIDRSKSYGSSKHYHLKYSRPALSRNSRSFTRSNNVLPTWSLDSNGEMRSRLSLSEVLDSGDLMKFAVDKTGCQFLEKAVKGSLTSYQKFQLFEQVIGRKDDFLKLSTNIFGNYLVQSVIGISLATNDDGYTKRQEKLKNFISSQMTDMCLDKFACRVIQSSLQNMDLSLACKLVQALPRDARLIAICVDQNANHVIQKVVAVIPLKNWEFIVDFVATPEHLRQICSDKYGCRVVQTIIEKLTADSMNVDLTSAAQNLRERALQRLMTSVTNRCQELATNEYANYIIQHIVSNDDLAVYRECIIEKCLMRNLLSLSQEKFASHVVEKAFLHAPLELLAEMMDEIFDGYIPHPDTGKDALDIMMFHQFGNYVVQCMLTICCDAVSGRRQTKEGGYDHAISFQDWLKKLHSRVTKERHRLSRFSSGKKMIETLANLRSTHPIYELQSSGHDSFKTDYFSTASEHDGPELEKNGIEEGSLMLEPRSNKSSVSVKFSSSGSHGDD