lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction.
Subcellular Localization:
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Domain:
The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils; Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).
Sequence:
MSSDQEMAIFGEAAPYLRKSEKERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVKTDAGATLTVKEDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNRKPELIEMLLITTNPYDYPYVSQGEISVASIDDQEELIATDSAIDILGFTNDEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQGLNSADLLKALCYPRVKVGNEFVTKGQTVEQVTNAVGALAKAVYDKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSSNFQKPKVVKGKAEAHFSLIHYAGVVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLALLFSGAQTADAEAGGVKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQIITRTQARCRGFLARVEYQKMVERRESIFCIQYNIRAFMNVKHWPWMKLFFRIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVSLLKEKNDLQLQVQSEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEIGNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINDLTAQRGRLQTEAGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHVRVVETMQTMLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQLQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQQRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRSAEAIKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE
The following text describes a protein:
Function:
May contribute to the sorting of ubiquitinated proteins and transfer them for further sorting/trafficking processes to the endosomal multivesicular bodies (MVBs) pathway. Binds to phospholipids, such as phosphatidylinositol PtdIns(3)P and PtdIns(3,5)P2. These phospholipids are involved in the recruitment of the ESCRT machinery to endosomal membranes (By similarity).
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein. Note=Localized to discrete punctae throughout the cytoplasm which are distinct from endocytic vacuoles expressing endosomal protein p80.
Domain:
The VHS domain binds phosphatidylinositol PtdIns(3)P and PtdIns(4)P; The GAT domain binds phosphatidylinositol PtdIns(3)P, PtdIns(4)P, PI(3,5)P2 and PtdIns(4,5)P2; The Asn-Pro-Phe (NPF) motifs, which are found in proteins involved in the endocytic pathway, are known to interact with the EH domain.
Sequence:
MVTELVDKATNELLIQTDWTTVLQISDILNRDPIHARGVVRQVTKKLKDRSRVILLALELADSLLQNCHCTHVYFAERTFQTELCRLIMNKKTKLNVKEKTLEIVESWGNAFQARHDVPGFYETYSFIKRSGYKFPPKPSDAPILNFNNSPAKRTVSTTILTNNSHSTTPPQANVPSFNNVSSVGSNNAGGGGSSSQPIKNQEISSIKGSTSVFNEMISFLNVEDEDPQENDLIKELFETCKQSQIRVKEMIESGSTNERDLNVLLKLNDEINNALNDHEACIKRRRAFVENGYKPVPPPQQQQQQQQQQQQQQQQQQQQQSHSNNHNGTTTTTTTNNNNKNPSYLTKHKELEEIDFFKAPDGISPYSVQQQLQPFQQQQFNSTYNPFAQPQPQQFQQQPQQQLQQQPQQQQGFNQRIQQPQQQADAFDLFVANRQQSNNNNNNNNINNTTSSFGANNPFANNSSNNNNTNGAIQPYIPNTAKSLPPVSQQLQQPMQNQFSPQPQKFVGSSITPSAPPPFKPNTTQSNPFNTSPPLNNMNNHNNNMMQQQQPQQQQQQQPQQQFNPMYNNNAMAPSYPNYNAIGADNQHNTNPYGMMNHQQQQQQQQQQQPMMNQMNNFSAPTYSQFTNYAQPNQQPYNNNYGGMNQSNMYPNNNMSGKSSLI
The following text describes a protein:
Function:
Exhibits ATPase activity. Binds DNA/RNA in a non-specific manner and exhibits endonuclease activity. Probably involved in DNA repair. Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing. May also be involved in the regulation of chromatin architecture to maintain gene silencing. Together with MORC7, acts to suppress a wide set of non-methylated protein-coding genes, especially involved in pathogen response. Positive regulator of defense against the oomycete Hyaloperonospora arabidopsidis (Hpa).
Subcellular Localization:
Nucleus. Note=Accumulates in discrete nuclear bodies adjacent to chromocenters.
Sequence:
MEPIVKQENPVTTSTLSTWKPAARNKTIPPPESVIELSSSNEGSELGENLDEIAEIQSVDRTGGDDVSGTKRARSDSIASPAKRLAVMIPDDDEEFLLSTTSGQAILALPATPCNVVAAPSSWGSCKQFWKAGDYEGTSGGDWEVSAGGFDHVRVHPKFLHSNATSHKWSLGAFAELLDNALDEVRSGATFVNVDMIQNRKDGSKMILIEDNGGGMNPEKMRHCMSLGYSAKSKLADTIGQYGNGFKTSTMRLGADVIVFSRCLGKDGKSSTQSIGLLSYTFLKSTGKEDIVVPMLDYERRDSEWCPITRSSVSDWEKNVETVVQWSPYATEEELLCQFNLMKKHGTRIIIYNLWEDDEGMLELDFDTDPHDIQLRGVNRDDKNIVMASQFPNSRHYLTYKHSLRSYASILYLKISHEFRIILRGKDVEHHNIVNDMMQTEKITYRPKEAADVSQLSAVVTIGFVKDAKHHVDVQGFNVYHKNRLIKPFWRIWNAAGSDGRGVIGVLEANFVEPAHDKQGFERTTVLSRLEARLLHMQKDYWRSKCHKIGYAKRQGRKSAKDTEKDTEDRESSPEFDPKGSASSRKRTVPSSFKTPTAAPRFNTPTAASEKFNPRSNVNGGGKGSVKVSKDIGYKSSEKGGKLGNSFSKSNKRAKPQGARAVEVTNSDDDYDCDSSPERNVTELPGKSSELPKPQSGPRTLSQLEQENNELRERLDKKEEVFLLLQKDLRRERELRKTLEAEVETLKNKLKEMDKEQASLIDVFAEDRDRRDKEEENLRIKLEEASNTIQKLIDGKARGR
The following text describes a protein:
Function:
Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol. Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.
Subcellular Localization:
Cell envelope. Endomembrane system; Multi-pass membrane protein.
Sequence:
MDMGSGPALQYLLCLAWVAATLPIAAAALPIPTAAGGRFIHGLLCAFSSRGKTVRPSVSSSSKTRFTVPQKFFLHFYVVGAVVTTSLLLAIWFYAYMKMTPLMPEPSSYSTIASHLVGGSNSFSLANFWSSRPMEHKHRVWRTVFVLILMEIQVLRRLYETEHVFHYSPSARMHIIGYLTGIFYYVAAPLSLASSCLPEAIQYLQYQIAEFIVKGRARMPDLAIDPSHLLKPLLKLGWCQWIGAVIFIWGSLHQIRCHAILGSLREHKDSDEYVIPCGDWFGRVSCPHYLAELVLYFGMLIASGGSDISVWFLYLFVITNLSFAAVQTHKWYLQKFEDYPRSRYAIIPFVC
The following text describes a protein:
Function:
A benzaldehyde dehydrogenase able to act on substrates with 3- and 4-hydroxy and methoxy substitutions; converts vanillin (4-hydroxy-3-methoxybenzaldehyde) to vanillic acid in vitro. The physiological substrate is unknown.
Sequence:
MFQYEELNKQFIGGKWQEGSSPNVLENKNPYTQKTFTTFRKATADDVDEAYRAAALAKKKWDAVNPFEKRTILEKAVTYIEENEEAIIYLIMEELGGTRLKAAFEIGLVKNIIKEAATFPIRMEGKILPSTIDGKENRLYRVPAGVVGVISPFNFPFFLSMKSVAPALGAGNGVVLKPHEETPICGGTLIAKIFENAGIPAGLLNVVVTDIAEIGDSFVEHPVPRIISFTGSTKVGSYIGQLAMKHFKKPLLELGGNSAFIVLEDADIEYAVNAAVFSRFTHQGQICMSANRVLVHSSIYDKFLELYQAKVESLKVGDPMDPDTIIGPLINSRQTDGLMKTVEQAIEEGAVPVKLGGFNGTIVEPTILKDVKPFMSIAKEELFGPVVSFMKFDSEDEAVDIANETPFGLSGAVHTSNLERGVAFAKRIETGMIHVNDTTINDEPNVAFGGEKQSGLGRLNGEWSLEEFTTLKWISVQHEKRSFPY
The following text describes a protein:
Function:
General amino acid permease with broad substrate specificity. Can also transport carnitine.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTKERMTIDYENDGDFEYDKNKYKTITTRIKSIEPSEGWLEPSGSVGHINTIPEAGDVHVDEHEDRGSSIDDDSRTYLLYFTETRRKLENRHVQLIAISGVIGTALFVAIGKALYRGGPASLLLAFALWCVPILCITVSTAEMVCFFPVSSPFLRLATKCVDDSLAVMASWNFWFLECVQIPFEIVSVNTIIHYWRDDYSAGIPLAVQVVLYLLISICAVKYYGEMEFWLASFKIILALGLFTFTFITMLGGNPEHDRYGFRNYGESPFKKYFPDGNDVGKSSGYFQGFLACLIQASFTIAGGEYISMLAGEVKRPRKVLPKAFKQVFVRLTFLFLGSCLCVGIVCSPNDPDLTAAINEARPGAGSSPYVIAMNNLKIRILPDIVNIALITAAFSAGNAYTYCSSRTFYGMALDGYAPKIFTRCNRHGVPIYSVAISLVWALVSLLQLNSNSAVVLNWLINLITASQLINFVVLCIVYLFFRRAYHVQQDSLPKLPFRSWGQPYTAIIGLVSCSAMILIQGYTVFFPKLWNTQDFLFSYLMVFINIGIYVGYKFIWKRGKDHFKNPHEIDFSKELTEIENHEIESSFEKFQYYSKA
The following text describes a protein:
Function:
O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis. Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid. Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone. Also able to mediate the methylation of 3-demethylubiquinol into ubiquinol.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MRGVAADEVAKFAALQKHWWDPTGPLRSLHLLNPIRVRYVNSIVRSFGNVGGSSCDTSIGFSRDSGLTPQHQVLDVGCGGGILAESLARIGGTVTGIDACAESIEVAEKRRQQLAANFNASSQVFNWPQRLSYRHVSLFDVVEQEKRQFDVVVASEVIEHVSDARAFLQALCEATKPGGLLFLSTMDKSLKTVIAYIGVAEMLTGLVEPGTHDWRKFIPPDDVTKFAQRFGVRKVDQHYIVTYPDVCQSVVSCNFQVNFFLSKNVNTGHYLWAGRKSSLEAGKQASVPSGEGCVPHAPEYKKQELSLQPHGNGRPDATESS
The following text describes a protein:
Function:
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
Sequence:
MQLDCRRSLPFSTQRTVTMVSANILALDVDQLNRDWQWMLSALQSVLQRGGDEKLAELLPVPGCKLDPAKAPADSVQLTQAYSIAFQLLSMAEQSSAAQFRDRIESESGMADLPALWGESLQQLIDRGWTADMIAAELPSMRVELVLTAHPTEAKRATVLAHHRRLFRRFQLRHQTDLPPWRRSENEEAIESVLSILWRTGEIYLDKPDLQSERRNVMDYLTVVFPKALQPLDQRLRQAWREVGLSEKAIADPLALPRLTFGTWVGGDRDGHPLVTPEVTEETLMQLRRGAVELMREELIQLARLTSVSAYWLPPTSDFLTRIAERAHAMGPAGAAAIARNPNEPWRQFINLMLASLPSEKTMMSGKEQHTYQRSRELLADLRCLHESLVAVDLGDVATSAVAPTMRIAQTFGFHLAVLDIRQNSAKHDTAIEQLLRAAGMADWKFASWDEDKRMKFLNEELANSRPLTHPDSSAGEEADAVLGALRVVTQYRSKHGADGLGALIVSMTRKTSDLLAVYLLAREVGLLQRTESGAVCPLPVVPLFETIDDLERSPEIYDGFLQHPITRNSLTAIAQREGATAPVGQVMIGYSDSNKDGGILASLVGLRHAQRKLTQVARSHGVRARFFHGRGGTISRGAGPTHRFIKSLPDHTIAGDMRLTEQGETIAQKYAHEPTAIYNLELFLAGVTRKSLADSRSEEPDHPLEPTLVKLAAWARTTYHELLHSDGFVEFFREATPIDAIEQSRIGSRPARRTGQQTLDDLRAIPWVFSWGQARCYLSGWYGVGTALKKLQTECPDEFDAVKEALRDWAPLHYLISNVATSVTAVDIEVMKQYAALVENPALRERFVTDIETQWKLACEMVEAVYGGPMESQRPNVQRMIALRSEGLRLLHRQQISLLQRWRSYNKMGEHTQADALLPALLLSVNAIASGLGTTG
The following text describes a protein:
Function:
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis.
Subcellular Localization:
Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein.
Sequence:
MSEGNQPKRVLGLPDVDPSQQDTFETPDPPESISNLADESSELVNESIDRSSLKPAKSHLKFANRKFNNDNEDFSDSIYKKSVPRTGGLLKNQTVFDILPSDESKVETPLQKFQRLQYEVMSFREEMQVIADNGGEVEKDIKGVDLTHQLADLQNQLSHLLENEKLQPILDENKQVIHYSQIQNNSSKKLISEIESFTQQSLSSSTTEQNTQQPSNNNTTTNITSSSSITPNHVTYELFYTGEQSKSQQLQRIQDLEKRLAKLETATGNKTTDSVPITQSILEIKEKLSLLDTTKIDVLQQKMKTVSKEMESLKIQDETSTKALTTNEKKINDIFETMNKWDIVGQQVPAIINRLYTLRSLHEEGISFSNHVSNLEKQQNDITSLLISNSSLMNKMDDSFKSNLLTIKSNIQQLESRIETLQNRQQQQQQ
The following text describes a protein:
Function:
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.
Subcellular Localization:
Secreted.
Sequence:
MLRLVLLAASCVLATQAMTTREMNEDVTFDSVELAQGRKLAGATVDTTLWAEGYTPGEVTTATDEERAAGVWPTSKGTVPLTKPKIVGPTTPFDGGMKTYKRSNVAFKSGAKMAKSSAVFVVQAGATLSNVIIAGGGGVYCELHNCALVNVWFKDSIQSGLHINSGTGITTITGGGARNVAHRVIYGQASGTVVVSGGFYMENSGRLFESCGTCGPVKRGIIVDGVVSVNPTAELIRVNANYNDRGTISKASITTSTNYPVCTRFNGGATPKKVGNGASPPVCSYSAAAVKVKSPVTQS
The following text describes a protein:
Function:
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
Subcellular Localization:
Mitochondrion.
Sequence:
MAAPMKWKRLVFSAYTPAFSWVFTRITDRFFRAHDRRRGSAVLLLAPLLAEADSAPLASSRPPGFTGVESLHSRFHWMADHVPAFKVPGGHIRVLHSPDEFYQAMKARIKTAKSRVVMASLYLGTGPLEQDLVDCMEEALERSQEDHTPDLKVSFLLDYTRGSRGKHNSRTMLLPLLQRFPEQMRVSLYHTPDLRGLLRLLVPERFNETIGVQHIKAYLFDNSLIISGANLSDSYFTNRQDRYVLLEDCKEVADFFAELVGAVGDVSMQLLPDNSVEMMEGRVHPYKGNRADFSESAQRRIMEVVNTARIRQSMLKTECSDHPDSNGTSPNDTWIFPLVQMKPLGIHLDEQVTKRLLTEAGGDAVVYLTSGYFNLTRTYMQLVLGAEADYRILMASPEVNGFFGAKGVAGAIPEAYVHLARQFYNKVCQLGQQSRVHLHEYHRPDWTFHAKGLWYYVGGRDCPCLTLIGSPNFGYRSVHRDLEAQIAIVTENEELQTQLQQEQEVLYQSSTQVSNSTFNQPDRHVKLWVKLVTPLIKNFF
The following text describes a protein:
Function:
Produces ATP from ADP in the presence of a proton gradient across the membrane.
Sequence:
MSSQIKLTKNSYRAEKQKLNMLGMYLPTLKLKKALLQAEVQSAIRLAAESTVTNEQARDRMYAFAELFSIPLYTDAVEQCFSVDILEKDVENIAGVEVPLLKRVVLTSPEYSLLDTPIWLDSLLASVKEYVVSKIYAENAQERLLLLEEELRRVSIRVNLFEKKLIPTTSQTLKKIAIFLSDRSITDVGQMKMAKKKIQQHKE
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MATGATHIYEYLSLPESLLQQLDQQRKDGFLCDITLKASSGNCTWMAHKCVLSAFSGYFKSLLATNEASEVQLDPVTEKGFNALLDYMYTAKLVLTKETAQDILVAAGFLEIVNVLSDCSTYLSGPEEQPAANQPNSDGQKESTEPGESVPPTQPQPVKRGRGRPKGSKGRPKQSAVLSDDDDDEVDLGKLVLQGDGPYTCDICQAQFTRRSKILAHRRRHAVERLFTCDICDETFSKKGPYLSHRRTHRGEESYSCKDCEAVFEDRAGLKKHRKQHGGGDNTFPCEECGNSFSSKDALIQHKRRHTGEKPFSCNECDAKFAQKASLIRHRRRHTGERPFACDMCDKKFTEKNNMLNHRRIHTGEKPFKCSVCGVTFRQLSTLIGHRRQHTNKGEKPFQCDVCNARFTQKSNLISHQRVKHTGEARFSCTLCTAQFNNRFHYTGHMRTHTGERPYPCDVCNARFALKANLQRHQSLHLKEKTTPRSTVEQTISQAQPVQVQLQLPQGVSAASHIQALVSQSGETIPIRVAAVSQPSQIHEIPHSTAQAVQIREITLELPQGIQLQNAHVQADLQENGQEAVQLAQPTVIQPTVMEVTQAGVMEVSQSEVMEVTQAGVMEVTQAGMEVDPQQEGQGSEHQQLTTRTIHILPDGTQQEIHLSADRTEQVVQLSSQEEVHIVEIPTTQGDMAIPQGEENPTQVMSDAVQLEVLAAVSQIN
The following text describes a protein:
Function:
Catalyzes the transfer of a sialic acid from a CMP-linked sialic acid donor onto a terminal alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid of an N-linked glycan protein acceptor through alpha-2,8-linkages. Therefore, participates in polysialic acid synthesis on various sialylated N-acetyllactosaminyl oligosaccharides, including NCAM1 N-glycans, FETUB N-glycans and AHSG. It is noteworthy that alpha-2,3-linked sialic acid is apparently a better acceptor than alpha-2,6-linked sialic acid.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted.
Sequence:
MRSIRKRWTICTISLLLIFYKTKEIARTEEHQETQLIGDGELCLSRSLVNSSDKIIRKAGSSIFQHSLEGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISQDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCVKQ
The following text describes a protein:
Function:
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells.
Miscellaneous:
MISCELLANEOUS: Binds heparin.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Domain:
The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure; Domain IV is globular.
Sequence:
MPALWLRCGLCLALLLPAARASSGSQVCDCNGKSRQCIFDQELHKQTGNGFRCLNCNDNTDGIHCERCKAGFYRQRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGDRCDRCLPGFHTLTDAGCAQDQRLLDSKCDCDPAGISGPCDSGRCVCKPAVTGERCDRCRPGYYHLDGGNPQGCTQCFCYGHSASCHSSGDYSVHKIISAFHQDVDGWKAVQRNGSPAKLQWSQRHRDIFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLSKTLPCGITKTYTFRLNEHPSSNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYIDNVTLISARPVSGAPAPWVEQCVCPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIPECADCPIGFYNDPQDPRSCKPCPCRNGFSCSVMPETEEVVCNNCPQGVTGARCELCADGYFGDPFGERGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGVHCDQCKAGYYGDPLAPNPADKCRACNCNPVGSEPVECRSDGSCVCKPGFGGLSCEHAALTSCPACYNQVKVQMDQFMQQLQILEALISKAQGGAVPNAELEGRMQQAEQALRDILREAQISQDAVRSFNLRVAKARTQENSYRDRLDDLKMTVERVRALGSQYQNQVQDTRRLITQMRLSLEESEASLQNTNIPPSEHYVGPNGFKSLAQEATRLADSHVQSASNMEQLAKETQEYSKELMSLVREALQEGGGSGSLDGAVVQRLVGKLQKTKSLAQELSREATQTDMEADRSYQHSLHLLNSVSQIQGVNDQSLQVEAKRLRQKADSLSNRVTKHMDEFKHVQSNLGNWEEETRQLLQNGKNGRQTSDQLLSRANLAKSRAQEALSMGNATFYEVENILKNLREFDLQVGDKRAEAEEAMKRLSYISQKVAGASDKTKQAEAALGSAAADAQRAKNAAREALEISGKIEQEIGGLNLEANVTADGALAMEKGLATLKSEMREVEGELSRKEQEFDMDMDAVQMVIAEAQRVENRAKNAGVTIQDTLNTLDGILHLIDQPGSVDEERLILLEQKLFRAKTQINSQLRPLMSELEERAHRQKGHLRFLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ
The following text describes a protein:
Function:
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Subcellular Localization:
Nucleus. Cell projection, pseudopodium. Note=Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle.
Sequence:
MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGGSGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITVFKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MVKVEVEPRAPVEGGCGNIVGRGVVDGDGGEENHVVEIAGDATVNGIIAGSVAGEGEFSAEKVAQEARSTDAPSSDVPDPSTILPNQLTIFFGGKVCVFDGIPAEKIQEIIRIAAAATAKSIETKNSTSVKPVLSPALNRAPSFSSTSTGASPAALSLPINPIPFCRSAADLPIARRHSLQRFLEKRRDRLVNKNPYPASDMKKTDVPTDIASIKEESPIA
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MVKVSVKWQKEEFALEVDETQPPVVFKTQLFSLTGVPPERQKIMVKGGLLKDDGDWNKVGLKAGQKLMMMGTADKLPEAPKDAPVFVEDLPEDQQEAALTKDASVGLINLGNTCYMNSTIQCLHSVPELKDALSLYKPQDGIGADNNHKLTLAAKALFKELDTSYKPVMPFNFLMLFRQLYPQFAQTGEGGAYMQQDAEECWSQFIYALSTRLRDTQGGGSSAVVNDLFGIDMTSTLRSEESGEESTEAETVYKLGVHISSEVNYVHEGIKHGLKGELEKNSSVLGRSAVFQKTSRISKLPQYLTVQFVRFFWKKDTQKKAKILRPVHYPMNLDVFDFCTEELQEKLKPARKKLREQEDLKAGLEKKNKGKGIEGATSATDAKEEKVAGDTEMSEAHEVATADAPKETSTADSKGAGPSSSSSEAAGSSKELTGIYDLWAVLTHKGRSADSGHYTAWVKQDKGGWTLFDDDKPIPQREDDILKLAGGGDWHMAYICLYKARVPSA
The following text describes a protein:
Function:
This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the c-Myc gene. May play a role in the initiation of DNA replication and in recombination.
Subcellular Localization:
Nucleus.
Sequence:
MADRDSGSEQGGAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGGAPGGLQHETQELASKRVDIQNKRFYLDVKQNAKGRFLKIAEVGAGGNKSRLTLSMSVAVEFRDYLGDFIEHYAQLGPSQPPDLAQAQDEPRRALKSEFLVRENRKYYMDLKENQRGRFLRIRQTVNRGPGLGSTQGQTIALPAQGLIEFRDALAKLIDDYGVEEEPAELPEGTSLTVDNKRFFFDVGSNKYGVFMRVSEVKPTYRNSITVPYKVWAKFGHTFCKYSEEMKKIQEKQREKRAACEQLHQQQQQQQEETTAATLLLQGEEEGEED
The following text describes a protein:
Function:
The small GTPases Rab are key regulators in vesicle trafficking.
Subcellular Localization:
Membrane; Lipid-anchor.
Sequence:
MQEEVQDDDAQKVYKIIVVGDMGTGKTSMIRRFVEGNFSEFYKITIGVDFANKIITADGVKCDIQLWDIAGQERFGSMTGVYYRESVGAIVVFDITRPSTFEMTKIWMDDIQAKVQTSAGEAVPTLLIGNKIDLKPENWGNKTEEMQKYAEENHYLQYFETSAKDGTNLEEAIQALASYIVKNNIEPESTRDLKGVDISETSKVQKTGCC
The following text describes a protein:
Function:
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.
Sequence:
MAAQDELSEGGMADLVRALELIHNPSSTNDLRRQALTFVESQKESKLAARNGFLLASRVENAPLVRYFGLTLLDHVLRHTSFTAADQVAILRDFVLKLAESIRPEDPAYYRNKIPQLWVEIAKRSWGLDWLAMDEILVQFWGASLVHKELVLSILETLSEDIFYREDTVSSLRGTDLNRALVEICTPLSVFEEIYPKREHHVELRCGTEGWLARTCEFLIYCVENLQASIQARDAALKALATLKSILVWAIPKAIMSTNCVSSIVRPLTCSDEQVLLAAVEALHALYSRSNFEIEDFQPLVHLMYETEYLTLLRKLYEWSIVGPDDIDDTRYTISKKLSEMLSYLAGFLEEKGFSLETAHGMNLTFFFHLLISVIQNQSLTVSIPVLHVWCKLLASERIGSTDLVTGLIPVLLSICTERLIRWESLPADSDNPTVIFLNEDIDTVPERHAFVGNYRRYCSSIIETIVQKRPQDAIPHILAGVDANLDNLYNGVEPFDVKTFSKNSLSLMRADTQFAVVEATLKGYNKWVSGHGKMPQQDDPILKQRIIKLIVDISSRALDKNPSFSLKVLEHILMTRLPDLVECPAYSEAVKELHGLASHELRRLAMRYADYFSTFYDLLEPKIKEITMANRVDDKLHMEHTSILLIIINAHAFHNPANWGGLPHDMRGVVERILTDRFWQAGISTGSRDEFYAKITASRSSLEGFASSVRGKVRAVRESCYSMLFSMSRLREHFYGFAELPGPLSQALFKDSPHLSSHQFSVLLNISRCLIDDCPVRFRAQFLPPMLATLFTNIDRKVTAEWDLIEQRKEGLADGDLTDEMKSESILRQLTYSAVLMVASLLDPQRGDPDDEPAEPSAPQPPPALSDSIRHFVLSSPEIFEPVMLFCTHALRMRDTRCCSIITRVIRSILQDFAPPNHSPTIVTIREFISSEVLKACITSVHEPYFVDMQKDLAQLIASIWVLYGSSSPTPRSVILSLPGMDEQRVASTEAALLRSTAARQQRALVLDLLEGLRGVSIAEQGKILGSREERRKARSALQERYMSNEMEGQQISKVDINDGPDLGGVADMFG
The following text describes a protein:
Function:
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGPEFEDSIPLVHSDNRTTTIYSVYIIISDIFSFVQWLLFKVLNLIIIDSPAFVLRLLSKNFEINLHLSSILATLIGVSVVTYLVIRYKFLTGYSHSNDQKEGAGKKGIHPASSKVFVGKSKQDKKPSNYLDEFLLAIKVFGYLDKAVFHELTKSMTTQKLSHEEILCLDESLGFSIVVEGVAQVYTKKSKENSSKYKQRYFEEIEEERDEFLILGDKQYQLLNEVKSGAPLSSLFSTLDLFRPRNKNEEMALTPNDEDGNSVVALNMDYLSKSEPATDSKLSNSDDDENGQDYPEIIVRPKKSHNNGTITIAIIPHTAFERVQSKYPKATSHIVTMVLTRLYKVTMSTVQNYLGLTSEILKSEIKLNEENATSLPRYFVDGLLERLNKKEEAEAEAENLPKKLKHHHRNQLQRTTSRYVSLDSKVKSNHPGDLLSSVPISRSEFQKKVLPKSSTTSLSDGDNKRMNFTDEMEETEENSLRVAIIENIFKMVGIEETNGIVERTGYFQSLSSSTSSSIVGLDSLNQSIMSGATTPTTKRSHPVFNNQGSLMNTINLAELRKPSTAENSTLPKLSGKKRLLSDMNIKDAFAKSLEIKYIGPDSTIVSQNSAITGLYYVIDGSLEIYNRSADVSAPNRYIYTVESGGIAGYLTSVVGFRSMVTIKTPKKTGAVVAYIPKNDYNKLLDKYYFLQLPVALKLKNLLSKQILTIDYALEWCHIPAGEVLCSQGDLANGFHVVLSGRFRVVRSTNKNTEKEDVEVLGEYGHGESIGEVEVLTASRRSNTLIAVRDSETARIPRSLFEMLSNENPSIMVSVSRLVASKVLASQYQPRERNFITSTTSQESFTSANYKTITILPTVSGLPVRQFAEKLVQALRQIGRNVIALDQASILTHLGRHAFDESLARLKLSGYFAYLEEEYETIVYICDTPVQSNWTSTCISQGDCILLLADAEDDSTTIGEYEQLLVKLKTTARTDLCLLHQDKVVRAGSTSPWLKNRIWVQGHHHIQMKFEQGANVLPHKKSFISDLAAKLSQNKAIKSTFEATKQHIKWYVKENDQSKVLKIYKDDFMRLARILSNEAVGLVLGGGGSRGISHVGVVTSLERHGIPVDIIGGTSIGSFVGGLYAKEYNIVSIYAMAKKFSKRISSVWRMLFDLTYPVTSYITGYEFNRGIWKVFGFAEIEDFWIKYFCNSANITNSTMDIHEKGYAWRFIRASMSLAGLLPPIAFNGCMLLDGGYLDNLPVNEMKKRGVKHIIAVDVGSVDDRTPMNYGDTLSGFWVLLNRWNPFSSHPNIPTMMDIQMRLTYVSSVNALEEAKRTPGVYYLRPPIDPYATLDFGKFDEIYKVGLKYADDLFADWKSKGKFPRIAGLVEKKKDGEEKKILYRRNSI