lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MLRWLRGFVLPTVACQEDEDSFGYKILFQNLDRDGDGLVDIVELQEGLRNWSSSFGVNSGAEIFKAGNTNDDSGLDFGEFMQYLKDHEKKMRLAFNSLDKNNDGIIETSEIIAALKSLGMHISEAQAKKILQSIDGDGTLTVDWDEWKYYFLLHPATNIDEIARFWKHSTIIDIGESISIPDEFTEEEKRSGDWWRRLVAGGIAGAVARTCTAPFDRLKVIMQVHSTKSRRMRLIGGFEQMLKEGGIRCLWRGNGVNIFKIAPETALKIGAYEQVLKTRLALGKTGQYSGIIDCGKKLLKQEGVRTFFKGYSPNLLGILPYAGIDFAVYEKIFTTGDTNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGIIEASEIVQSLQILGLTISEQQAELILQSIDTDGTMTIDWNEWRDYFLLNPATDIEEIIRFWKRSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKVMMQVHGSKSGKMNIYGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAIKFWVYEQYKKLLTEEGQKVGTFKRFVSGSLAGATAQTIIYPMEVVKTRLAIGKTRQYSGIFDCAKKILKHEGMGAFYKGYVPNLLGIIPYAGIDLAVYELLKAHWLDNYAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMIEGNKPMNMVGLFQQIISKEGIPGLYRGITPNFMKVLPAVGISYVAYEKMKQTLGVTQK
The following text describes a protein:
Function:
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
Subcellular Localization:
Cytoplasm.
Sequence:
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQDALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKKNCIKDKKACIFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRIAKIQKIAPFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLNACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDTSHHSSSQCVGGMVVYENNAFQKNSYRRYHLKGSDEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGSFVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGIGEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI
The following text describes a protein:
Function:
Required for neoxanthin biosynthesis, an intermediary step in abscisic acid (ABA) biosynthesis. Probably not involved directly in the enzymatic conversion of violaxanthin to neoxanthin. Cannot convert violaxanthin to neoxanthin in vitro. Required for ABA biosynthesis in response to drought stress. Required for neoxanthin biosynthesis which is involved in photoprotection of photosystem II (PSII). Neoxanthin acts as an antioxidant within the photosystem PSII supercomplex.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing ABA4 have increased levels of trans-neoxanthin.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MGFSSFISQPLSSSLSVMKRNVSAKRSELCLDSSKIRLDHRWSFIGGSRISVQSNSYTVVHKKFSGVRASWLTTTQIASSVFAVGTTAVLPFYTLMVVAPKAEITKKCMESSVPYIILGVLYVYLLYISWTPETLKYMFSSKYMLPELSGIAKMFSSEMTLASAWIHLLVVDLFAARQVYNDGLENQIETRHSVSLCLLFCPVGIVSHFVTKAIINNQYK
The following text describes a protein:
Function:
Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
Subcellular Localization:
Cytoplasm.
Sequence:
MAARNLEKMASIDAQLRLLAPGKVSEDDKLIEYDALLLDRFLDILQDLHGEDVREFVQECYEVAADYDGNRNTEKLEELGNMLTSLDPGDSIVVTKSFSNMLSLANLAEEVQIAYRRRIKKLKKGDFADEASATTESDIEETLKRLLQLNKTPEEVFDALKNQTVDLVLTAHPTQSVRRSLLQKFGRIRDCLTQLYAKDITPDDKQELDEALQREIQAAFRTDEIRRTPPTPQDEMRAGMSYFHETIWKGVPKFLRRVDTALKNIGINERVPYNAPLIQFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYFSQIEDLMFEMSMWRCNEELRVRAERQRCAKRDAKHYIEFWKQIPANEPYRAILGDVRDKLYNTRERARQLLSSGVSDVPEDAVFTSVDQFLEPLELCYRSLCDCGDRPIADGSLLDFLRQVSTFGLALVKLDIRQESERHSDVLDAITTHLGIGSYKEWSEDKRQEWLLSELSGKRPLFGPDLPKTEEVADVLDTFKVISELPSDSFGAYIISMATAPSDVLAVELLQRECGITDPLRVVPLFEKLADLESAPAAVARLFSIEWYRNRINGKQEVMIGYSDSGKDAGRLSAAWQLYKTQEELVKVAKEYGVKLTMFHGRGGTVGRGGGPTHLAILSQPPDTIHGQLRVTVQGEVIEQSFGEEHLCFRTLQRFTAATLEHGMHPPVSPKPEWRVLMDEMAIIATEEYRSVVFKEPRFVEYFRLATPELEYGRMNIGSRPSKRKPSGGIESLRAIPWIFAWTQTRFHLPVWLGFGGAFKRVIQKDSKNLNMLKEMYNQWPFFRVTIDLVEMVFAKGDPGIAALYDRLLVSEELQPFGEQLRVNYQETRRLLLQVAGHKDILEGDPYLRQRLQLRDPYITTLNVCQAYTLKQIRDPSFHVKVRPHLSKDYMESSPAAELVKLNPKSEYAPGLEDTVILTMKGIAAGMQNTG
The following text describes a protein:
Function:
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Plays a role in dorsal closure.
Subcellular Localization:
Nucleus.
Sequence:
MKTPVSAAANLSIQNAGSSGATAIQIIPKTEPVGEEGPMSLDFQSPNLNTSTPNPNKRPGSLDLNSKSAKNKRIFAPLVINSPDLSSKTVNTPDLEKILLSNNLMQTPQPGKVFPTKAGPVTVEQLDFGRGFEEALHNLHTNSQAFPSANSAANSAANNTTAAAMTAVNNGISGGTFTYTNMTEGFSVIKDEPVNQASSPTVNPIDMEAQEKIKLERKRQRNRVAASKCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGCTVPPNSTDQ
The following text describes a protein:
Function:
Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.
Subcellular Localization:
Nucleus, Cajal body.
Sequence:
MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSEEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYFSSMAEFLKVKGEKSGLMST
The following text describes a protein:
Function:
Catalyzes the hydrolysis of N-((2S)-2-amino-2-carboxyethyl)-L-glutamate (ACEGA) to form L-2,3-diaminopropionic acid and 2-oxoglutarate. Involved in the biosynthesis of L-2,3-diaminopropionic acid (L-Dap), a precursor of staphyloferrin B and antibiotics.
Sequence:
MNREMLYLNRSDIEQAGGNHSQVYVDALTEALTAHAHNDFVQPLKPYLRQDPENGHIADRIIAMPSHIGGEHAISGIKWIGSKHDNPSKRNMERASGVIILNDPETNYPIAVMEASLISSMRTAAVSVIAAKHLAKKGFKDLTIIGCGLIGDKQLQSMLEQFDHIERVFVYDQFSEACARFVDRWQQQRPEINFIATENAKEAVSNGEVVITCTVTDQPYIEYDWLQKGAFISNISIMDVHKEVFIKADKVVVDDWSQCNREKKTINQLVLEGKFSKEALHAELGQLVTGDIPGREDDDEIILLNPMGMAIEDISSAYFIYQQAQQQNIGTTLNLY
The following text describes a protein:
Function:
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.
Sequence:
MNIKKEESLVYPQGSYSSECNYCGESENGRICFGMTCYQLTVEDYQSLIDIGWRRSGTFLYKPDNPNGCCPQYTIRLEALNFRPSKDNIKTKKKFQNYIAFDEKPNKTKIINEHNQMDEDDNRPSKTTQPSTSTSTTSTSTTSNPTLSKSPTLPNIIYDLNKFIIEILHKFEFASNSFSDINSKKTIENNLKIKINAKKSIKEKGNYSISFGIFNKFKKELEESLISIDQIIDFILNYYSNDKNQFIEQFKLTLGENNHINIIDLKNTDNHITSHNNSNNSNSNSNNKTSKLKNIDPSKVTPKHKFEVTIHKPQCTDEVFNLYCKYQTIIHKETDKKTKSGFSRFLVDTPLIEVPHAEGTDDEESNNDEAKEREDETRYLKTKKFGNIKVPKPGYGSYHQYYRIDGKLVAVGVIDILPLCLSSVYFFYDPDYNFLNLGKYSSLLEIDWVRRCATVEGISQLKYYYMGYYIHTCQKMKYKGKYQPSQLLCSENNVWVEFNKAISKLKDKRYSKFYFENEEQEQEQVETKGKSNEKTKTFYEKDNSLLDSTRFKQGNMYFKYSEITPRFQKMLKDHVIEYINHVGELSKDLIFTLK
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
Subcellular Localization:
Nucleus.
Sequence:
MSANPVILEDTFTVNGVNTEGTVYLRVSRIRCVNQDGSLTITTDINSEEFPVSTNDRLTIVLANSLELGGKTGSKYYDHSVYHRETRLNDCDYAMHGRVYGHEVVENGLEVNVHISCGGLLVNIVGKPQGLRDVHYNSDVYILIKRVKN
The following text describes a protein:
Function:
Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively.
Miscellaneous:
MISCELLANEOUS: Present with 1420 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MLGRALINKYGFLIHPRRFVHLNDKSLDGTFILPSKKNHMYDVPTNDPSGILNASDIDRINNLPFFDNTSPTKETNTKEGALLSEKLASVKELFGEDPENPSFINYRFPRGLENPYFDIQVNQLKKKRLSVTQLCTTQNWCELRNFYDFYSQNLSNQLLNLKFQVQKGKKIHKSLEDETHPELNQYKSFTHNFLALTKLSMDIDNDMDALLDNWFNSINRLVSLFTKGDGHAREIVCHGFINLEDGKLVEHLLNSDSKTKENVIISGVIDHLTLRNRHNHQVQKGAAHLDTEYQSWGNILTNLLSNLKELKSNNEIVISDIKTRSVPKIPSIESVIESSKLQTMYYKFFFSHLSQDMTQTYHSFLINAQRRGLDVDAPINPTKILTFILTNPLFANDVKNLLYGLPINHSAFDNDAKGSNTFDMTAFNDLLDRGPTSFNVPIEQDEDSSESTKCVSLRDYGHFYTKWKTPLTLKYFAARLSQIYFIVGNLVSNDLMIEYYYHNDNFHNIIFPYDPLKLGTHAHDSAMVWFGGRDMHPIEPTQKNFNTYCKFCDYRHVCSWKNKNELKLIDLGKELKKIILESSMK
The following text describes a protein:
Function:
Probable E3 ubiquitin-protein ligase which is a subunit of the N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation at the 5'-[AG]GAC-3' consensus sites of some mRNAs. Associates with MTA, MTB, FIP37 and VIR to form the m6A writer complex which is essential for adenosine methylation at specific mRNA sequences. N6-methyladenosine (m6A) plays a role in mRNA stability, processing, translation efficiency and editing.
Subcellular Localization:
Nucleus speckle. Nucleus, nucleoplasm.
Sequence:
MLQIRLRRDSPTETGNGARPSPTETVTVACPDHLVLADLPVAKGIGSVTPTTVIKPVGRRSRRQLGERVHFCVRCDFPIAIYGRLIPCDHAFCLECARSDSICYLCDERIQKIQTIKMMEGIFICAAPHCLRSFLKKLDFEAHVHDLHGSLLQADAEKEDGNQSDVQSTMQQSSASESTLRAPLRSQLQQSRELNRSASFAKSQSGFSQVQNYPPDSDNSRPPGFETASPKPGIRFPDYPQPMNLMQPPSLPVPMNQNPGLPQQFGFPSYPTTESGSSQQFFNGAQYEMTRTESGGSEQSSLLGYPPPSPMTNLNFQGSYPPPSWNPGMAPPHTTQQVNRGRDGQSFGWPQENRDGFGQE
The following text describes a protein:
Function:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MAELDVGRFYERLNKIHDHFLKHREGTMWNGANCISINRGASTDDENPYLKSTILHNYLFGYELPDTVLLLTKEGRCIILATKKKCEFMEPAVEKVTGSIAELKLLVREKTDGNAANFEIMLQAAKVDRNGVNVKIGVIMKEFKKNDGKEGSIVAGWEKKLGEDSSKVDIVDVTAGISLVMAVKDATELDLIKKSSVLSNKVLKHKFIPRIEAIIDEGLKATHDELAQEVDETIEDPSSINLKVQKDVVQSCYFPIIQSGGEYDFKVSALSSSKNVTYDVITVSLGARYQMYCSNIARTILVDPPKEVSANYETLLGMYQNCLHAMVPGKPLKGVHAAAVAYLQKQGKDDLIPLLPKSLGFSIGLDFRDPLLVLNSKSTVTFRKGMVFNLAVSLAGIKLSAAVNSKSADLSEYGLVVADTVVLHENGADAMTKYGKDLTDISYTINDDEEDEGEDSDDDDADAKLAKKLAKEEELDPSGGRRSGRLAANMSSAQETEGAAERERKQIDLMARKNEERLRELARASKKKGGDEKAKKAEELEAYKRTKDLPDNVLPNQVKVDMANQCVILPICGNPVPFHISTIKNVVLPDPDSAAYLRINFYTAGMAVGKDAPENTVKLIQKYSPYATFIREMTFRSLDSHSLTTAFRQISELRKRARMKELQDQEEANLVKQDKLVRTKNERVPRLSDLTMRPVFAGRKTQGNIEAHSNGLRFISSRGEIVDVMYSNIKHAIFQPCESEIMVLIHFHLKNPIMVGKKKQQDIQFFTEVVDASQAVDAGKRSMYDPDEMDDEQRERQLRKRLNEAFKEFCRKVESVARKNGYSLEFDIPYRDLGFTGNPHKEMVFIQPTLNCLCNLTETPFFVVDLSLVDHVHFERVTFMSKAFDMVLINKDFTKQPWRVDMIPNDDKDSIQEWLTDMEISYTEGPMNLNWKQIMSTVDGDDRFYMDTEEDEVTPKEAGWEFLRMFGKDDADSGESEENDSGYSENSGSEESEEEEEEEEEDFDSEDSGSEFDADEDLEEQGMDWDEMEREAAADDRRKKRDGDDEPARPAKRRQRR
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Subcellular Localization:
Nucleus.
Sequence:
MGKPKQQVISRFFAPKPKNEKDPSTSASTPPCTPPPKITATVTFSPAKRLRNSQLTSPPPTKHTKIPKLSPHVHNPPPPLPNPTLHQRFLDKLLEPSTDLLEPSKCYDIQNPKYTPLEQQVVELKAKYPDILLMIEVGYKYRFFGQDAENAARVLGIYAHMDHNFLTASVPTFRLNVHVRRLVSAGYKVGVVKQTETAAIKAHGSNKLGPFGRGLSALYTKATLEASEDVGGGDEGVGSCNNYLCCVVEKGMEDVDFGIEGCRGVDVKIGVVGVEVSTGDVVYGEFNDNFMRVGLEAMILNLMPAELLVAKPISKQTEKLLLAYAGPASNVRVEDVSSDRFSDGGALAEVMSLYEGMQEHYLSNVQEREEAEVKMHEHNRITIQGMMAMPGLAIQALALIIRHLKQFGLERVLCLGASFRPFSCNMEMTLSANALQQLEVLKNNFDGSESGSLLHCMNQTLTVIGSRLLRHWVTHPLCDRNMIAARLDAVSEIAESMKTYRTSYTSFLEVEGADVTISQPEIHHIISSVLSTLGRSPDIQRGITRIFHRKATASEFIAVIQAILTAAKQLQQLWIEEDKSTNLQRETLRSVLLRKLISVASSSTVINAAAKLLSALNKEAADRRDLHNLFFISDGKFPEVAEVTRRVELANEKLDSLIGVYRKQLHVRNLEYMSVAGITHLIELPLDTKVPPDWVKVNSTKKAIRYHPPEVLVALDELALANEQLTVVCQAAWNKFLTSFGGYFAEFQAAVQALASLDCLNSLAILSRNKNYVRPLFVKDDEAVQIHICSGRHPVLERVLQDNFVPNDTDLHAEREYCQIVTGPNMGGKSCYIRQVALIALMAQVGSFVPAFSAKLHVLDGIYTRMGASDSIQQGRSTFLEELSEASDILKKCSASSLVILDELGRGTSTHDGVAIAYATLQYLLEHKKCMILFVTHYPEIVSIKNEYPGSVEPYHVSYLTSQRDVNGDFKSNEKMDLINTEDITYLYKLAPGVCERSFGFKVAQLAQLPVACIQRAIVIAGRLEAAVSNYTVQNRTRRSSSISYSIDGCKESEPVEYVLEPDCLSAGRAERLDDMSELYRELFLNLNFALLEEHDDDRRLQFLMQARGLAAQLISSCISS
The following text describes a protein:
Function:
Involved in serotonin biosynthesis. Catalyzes the conversion of tryptamine to serotonin. Accumulation of serotonin may play a role in innate immunity.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MELTMASTMSLALLVLSAAYVLVALRRSRSSSSKPRRLPPSPPGWPVIGHLHLMSGMPHHALAELARTMRAPLFRMRLGSVPAVVISKPDLARAALTTNDAALASRPHLLSGQFLSFGCSDVTFAPAGPYHRMARRVVVSELLSARRVATYGAVRVKELRRLLAHLTKNTSPAKPVDLSECFLNLANDVLCRVAFGRRFPHGEGDKLGAVLAEAQDLFAGFTIGDFFPELEPVASTVTGLRRRLKKCLADLREACDVIVDEHISGNRQRIPGDRDEDFVDVLLRVQKSPDLEVPLTDDNLKALVLDMFVAGTDTTFATLEWVMTELVRHPRILKKAQEEVRRVVGDSGRVEESHLGELHYMRAIIKETFRLHPAVPLLVPRESVAPCTLGGYDIPARTRVFINTFAMGRDPEIWDNPLEYSPERFESAGGGGEIDLKDPDYKLLPFGGGRRGCPGYTFALATVQVSLASLLYHFEWALPAGVRAEDVNLDETFGLATRKKEPLFVAVRKSDAYEFKGEELSEV
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MARKGVLTIGERFCIWLLMVGGVLPFQYVVSTNRFVQSTFHYRGCIVGTVLYAMVGPWLYWISVTRILHPDSQLNQYMIVVQFICMYVVTLTSRLKTLANRERLCQLLNALLVLREQVLQGSTKAATFQQGLARSLLTKLIVFDLGMMVLSAAFFRTFIELKQSLIYSILGVCNLLQISSMNVAVNLLMFVLYSGINIYARINAHCNDLVYGSKAPNEIVRLYLMHTEASLVVQSIVEVISIPILLLSVWYFFIIVFSVSRCRWRVCALYGILTTVLYRSVQIFYTYTSLVQDLEAGSTNALRNIINPLAFFISEVGQVYFMVSSSATFSRQARQIIPCLSMYTGRITDVPGDRAIELLTIEYLNRDYAIRIKGLFTIDNTMLFGIVASTTSYMIILVQYYLQE
The following text describes a protein:
Function:
May play a role in apoptosis regulation.
Subcellular Localization:
Nucleus.
Sequence:
MSGLPREILKWIQSLDLSHPVKNTKRDFSNGCLVAEIFSWYYPQEIQMHSYDNGASLATKMGNWSQLQTFFQRQGFGIPKEVIDGTIHCKPGAAALLVEKIYTLLTNRVVKKVRTDDELDFTDTGYQAQLPAHARSTASMAIKNNIANTELSTDPDRILCQQKAQSIINSHVEHRRKERSDDPHRFGIKPTLGELCPRSAPRPSHHLSRNTEENFQQKQTSEQELSFSGEPPAHYTEVQVNQLPNGSDNIMHSTHSGALYNMVH
The following text describes a protein:
Function:
Member of the pre-replication complex. Component of the plastid division machinery. Promotes polyloidization and regulates endoreduplication. Involved in the coordination of cell and plastid division.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MSTPGSSRSIPFKSKKRLVMDSPSSKSQTGNPNPSSVALPTPEKPLENMLSRSRNRSVALSVKEIRQAAGSRRRSEDPVASSAKSRLFFDSSSSSPSKRKSSNKNAEKEKLPEKYENLGKFFEALDNSMLLSKLRGSKPTFSNISKQIEHLTERRFCYSHLAQIKHILPEAIEIKRVLIHDETTCCMKPDLHVTLNADAVEYNDKSKSESKKIALRKVFRARLADFVKAHPQGDEVPEEPLPEPFNRRKPVENSNVEVKRVSSLMEEMASIPASKLFSSPITSTPVKTTSSLAKPTSSQINIAPTPTKPTSTPAKQTLSEINILPTPVKPVSTLAKFPSTPAIIDSTPVITATPPEFASTPARLMSTSLAARPLKRSNGHTNPDDISADPPTKLVRRSLSLNFDSYPEDERTMDFTDDIPIDQVPEEDVSSDDEILSILPDKLRHAIKEQERKAIEDQNPAISLAKRRRKMIACLPKLFNVIHYLIQSIRRWVITKEELVHKIIAGHSDITDRKEVEEQLILLQEIVPEWMSEKKSSSGDVLVCINKLASPLTIRSRLEEENKQEMAPLLS
The following text describes a protein:
Function:
May negatively regulate Notch-induced cell proliferation in the eye-head primordium. May act in leg and wing primordia to negatively regulate body-wall specifying genes and thereby promote appendage formation. Required for tracheal development.
Sequence:
MLQSSNHHYLRPDYMTAAAAPTAQLDNKSSPLALLAQTCSAIGADTTNPKLLAANIEKSTKQLQHHPKGSSGSGGSGSFGLSQQASMDGSARDKSSPVSSHSSSVSTGSVEQQQLPPAHGSSSSSKPTPTTFKPYEPNNNISNITTAADCGATNLSSNNTSAQQRVKTPKSMTNGGGQRCDSNQSASSQHRESPTAAGSLRRTPTSGLAGGVMQHNGSPGLPPTASTTPGRSNSKESAAMHSPSAAAAAAAAAAQIASSNRLQEAALAAAKEANYVKALHAASQQGSASAAAAAASYYPPGYGSPYSMDLMTASSLMSPHHAMFKASAMNPYLNYARMKGLTEQSMMAATPNVCRDPYCTGCPASPHYINKAAGQPCPAGCPQCEGGGGGGGGSSKSSGSQGGSGGSSSAAAAAAAAAASSYHAQLAALAAASQMPYVCSWIGSDAAYCGKRFGTSDDLFQHLRTHTASVPDAVLSAAAAGGIPPNHPLFQRTYPTPPLSPLSAARYHPYGKPSMLPPSLAPPGMPGLPPHPALAQYFAPYSLYGPRMGSSHP
The following text describes a protein:
Function:
May play a role in the regulation of cytokinesis.
Sequence:
MATPAAPEGAAPADHRPALTVEELCFASAMSCFEGWLKMDPAIGPRTMSYVTKFISRTLEKTHNLKEVRETLSRSVEVWVWLTKSFAAALPSLTTRSIGPLQSLNDPEKGITPQESTALITKNYTSLKEDLQLLIKLMHIARNLLVVPEPEIPQDLCAAAQFDKMLYQTITLCVNVTSKAYDGDILEETARHKLSEITELYKKLLITCLQQAHNWIAKNDRNKMSFWCAVLFDDESGEEQQDAGAQFADFRPDVAKMEVHNWIERNSRMCDKARQLLIDYQRNLGSRGSPPGSLPENSVLSWNWMPHVRPRADDIGEETKITPQWKEDEQDKFEQDRLYGRVSREVDTWWLKVRDPNYDEWIISMPSVEKAHQLIEGCKLSSLNRYPHSFRNEDQEGSVHSAEDVQLPEHQGPEGEIRDDRHYNLPDYNDDMIEDEDADDDESYGEGPMSGLLTEVPNILDPKQIEALHMIVKSCILDSAGISLSRAGENLQKTRCRMFLSLECGRSLLREILVFIAVWEKSEQSLIFQLTTQIVEAIHHSALIPFAWQSLRIPKDIISPAQTVLLRLVNNMFRTRLQDPIQPGSKGHLRDIKLLQFLYIQFRTRIVPECTALMHLQAQIRNETCDPVDFPVDSWDMERAKDGLQQFLDLLMTVNEPIEWRTCLIQWEAVFDLLVLLKSLESAVPKKPMVDLPDRSAHRRPPPPHDDDRESHDYDSADPPPPPPPPPIQEHAHKFPWAGIKGQILHIIAGLLQPEAGRSGPGNPVVQKQILQHNGIISLLNCCVYDDHNRFARERVQICLKWLMDGSAEANKVLHDLVAVSPPPNLQSAPDASGLTQPVPLRVDGIAGEVKVRVKSNNAPPGSSPSSSAQQQQQHHPSAAHQQYPPRPSSAASNESGITTNSNTSTSSSTHDHDHLSSQAAPSASNNNKNNNTHTHQPPARVHGPAPPPPTPPSALTLPSLASPLISVSPSDYERFTKAYMNALPPLHSAATGVPGVGGHLNHPMMQAVRNHGGRPEDLFKDILTLADEAARLAIGQPPFVSPSGSGIGSGSGSGSGSRQRDAEETEEEDFM
The following text describes a protein:
Function:
Cadherins are calcium-dependent cell adhesion proteins.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MHCGKWLSLALTVAQFSPCFLCKPRCDSEDMEHIFVRSRSMKLSGILKMPFVHEERILTQPLISGQTKSDVQKQDSSLADNWPQFLDGPYEATVPEMSAEGTSVIQVTARGPDSMGARLFYSIPPEQPYFSVEPTTGIIRTLYPVDRETQDQYFVLIQARVGQASERSATTTVTINISDVNDNPPRFQHKRYDMYVSETAPIGSMLGKIMADDNDIGDNAAMEYIIEEEPPHIVYIITDNKTQEGAVILNKTVDYETQSVYDIRVKGINRHVDQRFLSEDMRFEDTAILRIRVQDVDEPPVFISKELLMEISEEEMNNSFVGAVSARDPDKANSPIRYSIVLSEYFSINAHNGTITVTRPLDREIAAWHNITVTATESMNLKQVSEVNVYIEVLDINEYAPEISEYYEMYVCENARSSQFIQTISAVDRDDPMEGHHFFFYLTEEATNISGFAIEDNHNNTARIVTTRNEFHHREQLLFPLLVLVADNGTPSLTSTNTLTVTVCECNEEVNVQSCRFGTILFSMGISVQALVAVVACILIILVFVLAIVALKQQTKPPLFHEKGEPFRENIVKYDDEGGGEQDTEAFDISALRTQPVLREHKPRRNITTQIQSLYRQSLQVGPESAIFREFIAQKLEEANSDPDVPPFDSLQIYAFEGIGSVAGSLSTLGSSSPDSDENEYYLLELDTHFKRTGTIHDSIPPKSGVLESAHGHKMEIF
The following text describes a protein:
Function:
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Miscellaneous:
MISCELLANEOUS: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Subcellular Localization:
Mitochondrion.
Sequence:
MSSLARWIITIGLEVHVQLSTKLKLFSRALAENHKAPNSAVSFFDISLPGTLPIVNPEAIRLATKAALVCNCEIAPSLEFDRKHYVYSDQRAGFQITQKRRPLGTNGFVRLNAALDGVEKDQLVEIKCLQLEQDTGKTVNELNEDLVLLDFNRANVPLIEVVTAPCFHSPHDAACFLRKLQTILRLANVSDAKMELGNMRCDVNVSVASAENPTKQLATVELKNLPSIRYVEIASELEAKRQIELLNNGSSPVPETRSYDVEKNATVFLRKKRGPSDYMYLPEADIPEITLTSAYVDDVRKSIGPSVDELLETLLQKKYFNLQDAKALLQTEDGLSYYQVLVGELEKVTSSMSPDVQLKAEKLIPFWLVNEYVGDCANAPDEKRDLDTIPPADLAFLLGNLANGTLSAYAAKHILQLAVQDPKKNSIYKLVNENANAEFDENTLKDLVNELIQANGDKVNALKVGKDGVLNWFIGNVMRRSSGKAKPDEIKRLINNTVLCENSSK
The following text describes a protein:
Function:
Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs). With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity). Required for normal duct development in the salivary gland and kidney (By similarity). Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (By similarity). Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (By similarity). Also regulates the expression of JAG1 and subsequent notch signaling in the collecting duct (By similarity). JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (By similarity). Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (By similarity). Modulates the placental expression of CYP11A1.
Subcellular Localization:
Nucleus.
Domain:
The Grh/CP2 DB domain is required for direct DNA-binding. The Grh/CP2 DB domain is essential to maintain the undifferentiated state of embryonic stem cells (By similarity); The SAM-like domain is required for homohexamerization.
Sequence:
MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGWRWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQEKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFGLGEGNASPTHPVEALPVGSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRDDLVQICGPADGIRLFNAIKGRNVRPKMTIYVCQELEQNRVPLQQKRDGSGDSNLSVYHAIFLEELTTLELIEKIANLYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESCFVLSTIKAESNDGYHIILKCGL
The following text describes a protein:
Function:
Believed to act as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons (By similarity).
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MLPAAMKSLGLALLALLLCPSPAHGLWCQDCTLANSSHCAPKQCQPTDTVCASVRITDPSSSRKDHSVNKMCASSCDFVKRHFFSDYLMGFINSGILKVDVDCCEKDLCNGASVAGRSPWALAGGLLLSLGPALLWAGP
The following text describes a protein:
Function:
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MADTTSVHETRFQAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCNISRPGFWDPIGRYKWDAWSSLGDMSKEEAMIAYVEEMKKILESMPMTEKVEELLRVIGPFYEIVEDKKTNRSSKLTSVRLEKVTKYLEELGNVLTSTPSAKTVNGKAESSDSGAESEEEEALEEVKQVKERENELKVEQESIANKDLEDVFTNGYDKDSLIDASSSINGTSTDEEVKKNQNLEQTGIATVWPQQDSNDDHVEDVSGIQHLTSDSDSEVFCDSMEQFGQEESLELLTSNRGALRYSPHCVAVDHSQLLENSGFPEEDRVSSENFRVEDMQERAGEGKGEVKRGGEDGRTNSGAASHREKRAGEKEEGSGFRRGRGHRMQHLSDGTQGGQMGSGGDGERWGADRGLRGSLNEQIAIVLMRLQEDMQNVLQRLHTLETLTASQAKSSALQSANYPPSSKPSWWPFEISPSALAFAIIWPFIAQWLVHLYYQRRRRKLN
The following text describes a protein:
Function:
Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Participates in the control of inducible RP4 gene expression in salivary cells (By similarity). Binds to the RIPE3 element of the insulin II promoter (By similarity). May be involved in the functional network that regulates the development of the GnRH axis.
Subcellular Localization:
Nucleus.
Sequence:
EFHDRLSYPPHSVSPTDISTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGARGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRAGGQAPSSPSYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCEQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPTSHSDIHSLLGPSHNAPIGNLNSNYGGSSLVTNSRSASMVGTHREDSVNLNGNHSVLSSTVAASNTDLNHKTPENYRGGLQNQSGNVVPTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAASAEPPTTLPGTHPGLSETTNPMGHL