lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MSDSHLMSTSNLQPLQSMAAGIDVATPLKKKNKPESQKRRDKKKNKKKRKIQKAKRAAAPKNKDWKPDPVLEALKQSTTFRKIDSVKGPKGDRTFEEYDTGTESGGQTTAQVPGDKEKKQQEKREKREKRQRKEERRARREAAITKMGVDMGPGEGTMVVEGIPEPDQVEEQEKNKSMPSLERSPTPPPLVAFPLPRLAPAPDASVLARQGLPKGLEDATFIDQSLRVEVEGLSVEGRDEALSVNMRRRLNEIGIEDFFAVQAAMLPRLLPLQLIPSPYCPLPDYLISAPTGSGKTLAYTIPILEILSQRTICRLRALIVLPTRDLVFQVRETMEALSKGTGLTIGTVTGQHSFAQERKQLVADLDTPLLGGSSKLDILIATPGRLMDHLASTPNFTLQHLRFLVIDEADRLLNQSFQDWLTQVLAYTRPPVEPIAPSFKRKPYDTVSSAFMEACGLVDKRGEWCDSSPSICQKLLFSATLTRDPSKVAALSLHHPQYYIVQSSSVPALPTSVGEQFALPSSLSEKMLILPPALKPLNLIHLIHHSEFNVDRALVFTKSVESAARLVKLLEFFEDAYVLGGGGGKRLVVEQYSGETRAKDKKQLLAEFGEGKVNLIVCSDLIARGIDLPSVSHVVSYDIPLDIRKYVHRVGRTARAGRQGTAWTLVEKQEALHFKGMLQNAGHLKAVKKVKVKEDDLSPYRESYEIAMKRLKDYYHHD
The following text describes a protein:
Function:
Vacuolar transporter that regulates zinc homeostasis by mediating zinc transport and storage into the vacuole. Plays a role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm. May also participate in the regulation of cobalt levels under normal physiological conditions and may be important in the supply of metal that is required for metalloenzyme or cofactor synthesis. Involved in the resistance to cobalt and rhodium ions.
Miscellaneous:
MISCELLANEOUS: Present with 2070 molecules/cell in log phase SD medium; MISCELLANEOUS: COT1 has a paralog, ZRC1, that arose from the whole genome duplication.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein. Note=Targeted to vacuole membrane via the AP-3 pathway.
Domain:
Contains 3 histidine repeat motifs between the 4th and 5th transmembrane, exposed to the cytoplasm, that may be involved in the binding site of zinc.
Sequence:
MKLGSKQVKIISLLLLDTVFFGIEITTGYLSHSLALIADSFHMLNDIISLVVALWAVNVAKNRNPDSTYTYGWKRAEILGALINAVFLIALCVSILIEALQRIIAPPVIENPKFVLYVGVAGLISNTVGLFLFHDNDQEHGHGHGHSHGGIFADHEMHMPSSHTHTHAHVDGIENTTPMDSTDNISEIMPNAIVDSFMNENTRLLTPENASKTPSYSTSSHTIASGGNYTEHNKRKRSLNMHGVFLHVLGDALGNIGVMLSAFFIWKTDYSWKYYTDPLVSLIITGIIFSSALPLSCKASKILLQATPSTLSGDQVEGDLLKIPGIIAIHDFHIWNLTESIFIASLHIQLDISPEQFTDLAKIVRSKLHRYGIHSATLQPEFITREVTSTERAGDSQGDHLQNDPLSLRPKTYGTGISGSTCLIDDAANCNTADCLEDH
The following text describes a protein:
Function:
Involved in pre-mRNA splicing. May also be required for cell cycle progression at G2/M (By similarity).
Miscellaneous:
MISCELLANEOUS: Present with 1770 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDGNDHKVENLGDVDKFYSRIRWNNQFSYMATLPPHLQSEMEGQKSLLMRYDTYRKESSSFSGEGKKVTLQHVPTDFSEASQAVISKKDHDTHASAFVNKIFQPEVAEELIVNRYEKLLSQRPEWHAPWKLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATALHPKEFSVASACTDDIRSWGLAEGSLLTNFESEKTGIINTLSINQDDVLFAGGDNGVLSFYDYKSGHKYQSLATREMVGSLEGERSVLCSTFDKTGLRLITGEADKSIKIWKQDETATKESEPGLAWNPNLSAKRF
The following text describes a protein:
Function:
Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. Forms a transcription repression complex with KNAT7 which regulates secondary cell wall formation.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing OFP4 show kidney-shaped cotyledons, round and curled leaves, small rosette size, late flowering, reduced fertilization and round seeds.
Subcellular Localization:
Nucleus.
Sequence:
MRNYKLRLSVMSPSEWFHKLKNMTKPRKKHSLPLYSINTTKKRKPSSESKSLPYSSTSYFFNRSRSRTSFESRILQISPRNSLHNIQSKRKTVYKPSPPSSSIVSAGFNKTFHQSHDSLSASSNLKVISSEDDIIIDMNNRDFKKKTFKEITKFDSTEKACRASNRTKETHIPHHLSVKVSKEKEDEEEDACRTKKKHQKTLVSSGRRSSAKSPRIKLRARSPRIQVSPRRSKSRSQNKQILDSFAVIKSSIDPSKDFRESMVEMIAENNIRTSNDMEDLLVCYLTLNPKEYHDLIIKVFVQVWLEVINSTFASK
The following text describes a protein:
Function:
VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MKQNSAAKLAFFELMVVVSNVQGNVGSADNSYVYKKLCTFVGLARNPTAPEAQLPVTPQELTDLETINATLSDPTWLDLFFKDGNDKDDIAEIPTQLKSNPGWSDNWGRWLQAAKLAKADTDKSTMKRFNLQTAAPANAKYIKTFVERALVIVNAKAAALADDITNTKQVTKEDIKKELVAAITGAADGVLTLPIKDNLFATAAAANMQTTCEAKDNTNGAATIGAVFACLCIKGNGQTGDQICDHSGAAIQWEAATGGPQMTDVKALIDGCPAMQDTTVTPELLVNTLRDIYSTISINSGNGYLRTFKTGNCQGHNANGFCVKISGLTSDDDTKFKQLPWVSKIINLSNDIGKVNKHNRAVHLLQAEARQQIAALKVLGRQPALTEFPPAPPTLDRRTQQAEEGKCKPQNTTPTECPTEHCEYDEKATDGNSCKPKPVKENTAETTGNQAGEAAATNRCTAHKDKLACENDKTGDKQNCAWRKGNGGEPEPEKEMCHDSSFLPDKKIAFSVVSAAFVGLVAFENYKDFCLIL
The following text describes a protein:
Function:
Binds DNA and may function as a transcriptional repressor.
Subcellular Localization:
Nucleus.
Sequence:
MNEHPKKRKRKTLHPSRYSDSSGAPKYIDNSGIFSDHCYSVCSMKQLSDNRGRFHYTVHSPDTDEDGSPVYAPWSGTQNNVMGSSFMDPKKKDKPSNNGIFKERCDSPLFSDSLTEEEKPLDIQTVEISTTEVQAVEVHDIETQTISPEKLEAEEAVEISVESCKVHDKNPPLNVTIQPKWPLLRANSSGLYKCDRCTFNSKYFSDLKQHIVLKHKTCSEGNICQVCKESFSSKKVLIEHLKVHEEDPYICKYCDYKTVMFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETSDPEDLHSHVVNEHAGRLIELSDSYHSRQQQGQYSLVNKISFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSGMLEYCKHLNTHMSEGIYLCQYCEYSTGQIGDLKIHLDFRHSAELPHKCTECLMRFGSEKDLLSHLQVHENA
The following text describes a protein:
Function:
ATP-dependent RNA helicase involved in pre-spliceosome/complex A assembly and mRNA splicing. Bridges U1 and U2 snRNPs during pre-spliceosome assembly and enables stable U2 snRNP association with intron RNA. Through its helicase activity probably catalyzes an ATP-dependent conformational change of U2 snRNP.
Subcellular Localization:
Nucleus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MSRRTRSRSPPRRSYNRERRDYRKYDDSEDQKGARYNRYVDDVSSRRDRHDSFRSHESNKIRRDNSWKHDKYSYEKRYQERDREYARSKNIPDQYIGRSPRPTSHRHAEEKEVDNKTKSDETNPVLQGSATEIKPQPRRSRFDRTERVGASLSVSEIQSENPRVDVIPKDKAVENNHQRNAEKPVASDKITDAKLLARLERVRAWKESKAKQEASKKEEHKLNTKPQVTAKDQNAMPSTGISGFEINRQKDTSDMKRNNRVHMDDEDGPRRMNLEDYQELWDQEDRGMLGNEQAASMEEDEVDPLDAYMASLVGTTDTIRPGLLNTEVIDPNANDDERMVISETLEEEENLLALAAKRSKKKDVITVDHSKINYEDFKKDFYVEPEELKNLSPAEVDELRASLDGIKIRGIDCPKPVTSWSQCGLSAQTISVINSLGYEKPTSIQAQAIPAITSGRDVIGVAKTGSGKTIAFLLPMFRHIKDQRPLKTGEGPIAIIMTPTRELAVQIFRECKPFLKLLNIRACCAYGGAPIKDQIADLKRGAEIVVCTPGRMIDVLSANAGRVTNLHRCTYLVLDEADRMFDLGFEPQVMRIINNIRPDRQTVLFSATFPRAMEALARKVLKKPVEITVGGRSVVASEVEQIVEVRPEESKFSRLLELLGELYNNQLDVRTLVFVDRQESADALLSDLMKRGYTSNSIHGGKDQHDRDSTISDYKAGVFDVLIATSVVARGLDVKSLQLVVNYDCPNHMEDYVHRVGRTGRAGHTGVAVTFITPEQEKYAVDIAKALKMSKQPVPKELQTLASQFLEKVKAGKEKAAGGGFGGKGLSRLDETRNAERKMQRKAYGEDEEDVETEAEAKSPLEKITPEKSTGDPTLDRVRAAVGGIAARAFANQTAQSNKLTQPISIIKTDGDEYKAKMEINDYPQQARWAVTNNTNIVHVTELTGTSITTKGNFYLPGKNPEPGEEKLYLWIEGPSELVVNRAITELRRLLLEGINHSLEGGNKPSASGRYTVV
The following text describes a protein:
Function:
DNA-dependent ATPase and 5'-3' DNA helicase. Unwinds D-loops, R-loops, forked DNA and G-quadruplex DNA.
Sequence:
MALSSAVKEQISQWYKALQQQIPDFISRAPQRQMIAEVAKTLSGDAGRHLAIEAPTGVGKTLSYLIPGIAVSRAENKPLVVSTANVALQDQIYSKDLPLLKKIIPDLKFTGAFGRGRYVCPRNLAAMCTDVSGQGDLSLFLGDELAPANGEEQATCLALSKSLNSYVWDGLRDHHQLALSDSLWAKLSTDKANCLGRNCHYFRECPFFIARKEIESADVVVANHALVMAALETESVLPNPKELLLVLDEGHHLPDVARDALEIEGEITAVFANMQLDMIVRLVDQCLVQYRPKNPPGLAHPERLKDHCEQLRELMLSVEQQVSQLLPTEGNPAVYRFEMGDLPENLTESCAKLFKLTDALRGVAEFVLNDLSEQTGKHDIVRLHRAMIQMSRTLGYLEAMSKLWRLAAMEKASNAPISKWVTREYRDNQTHIYFHCVGIRVSDQLDKMLWRKVPHVIVTSATLRSLNSFARLQEMSGLSEKAGDRFETLSSPFNHIEQGKLIIPKMRFEPTMANEAEHLAEMAQFFRAQHASGRHKGMLILFSSHRAMQTFLSHVTDLRLMLLVQGDQPRYRLVEEHRKRVNNGTASVLIGLQSFAEGLDLKGELLTQVHIHKIAFPPIDSPVILTEGEWLKSLKRYPFEVQSLPSASFNLIQQVGRLIRSNECRGEIVIYDRRLLTKGYGARLLAALPVFPIEQPDMPEGPLVTPTAVKGPAKRTKRVRKTRDKP
The following text describes a protein:
Function:
Antimicrobial peptide. Has low activity against the Gram-positive bacterium S.aureus (MIC>100 uM) and the Gram-negative bacterium E.coli (MIC>100 uM). Has weak hemolytic activity against human erythrocytes.
Subcellular Localization:
Secreted.
Sequence:
MFTLKKSLLLLFFLGTINLSLCEEERDADEEERRDDPEERAVQVEKRILPILAPLIGGLLGK
The following text describes a protein:
Function:
Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.
Subcellular Localization:
Cytoplasm.
Domain:
The UIM domain is required for protective effect on PP2A.
Sequence:
MAAEDELQLPRLPELFETGRQLLDEVEVATEPAGSRIVQEKVFKGLDLLEKAAEMLSQLDLFSRNEDLEEIASTDLKYLLVPAFQGALTMKQVNPSKRLDHLQRAREHFINYLTQCHCYHVAEFELPKTMNNSAENHTANSSMAYPSLVAMASQRQAKIQRYKQKKELEHRLSAMKSAVESGQADDERVREYYLLHLQRWIDISLEEIESIDQEIKILRERDSSREASTSNSSRQERPPVKPFILTRNMAQAKVFGAGYPSLPTMTVSDWYEQHRKYGALPDQGIAKAAPEEFRKAAQQQEEQEEKEEEDDEQTLHRAREWDDWKDTHPRGYGNRQNMG
The following text describes a protein:
Function:
RNA-binding protein which recognizes the 5'-UACUCAU-3' RNA consensus sequence. Binds sequences in both the 5'coding and the 3'-UTR region of rme-2 mRNA. Binds sequences in the 3'-UTR region of cye-1 mRNA. Binds to cyb-2.1, cyb-2.2 and cyb-3 mRNA. Binds sequences in the 3'-UTR region of tra-2 mRNA. Binds to the 3' UTR of Notch receptor homolog glp-1, thereby repressing glp-1 translation in the embryo. Binding to the glp-1 3' UTR is inhibited by pos-1 binding to an overlapping binding site in the glp-1 3' UTR. Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Represses translation of the vacuolar ATPase component vha-13 in the distal gonad. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation. By regulating cye-1 expression, prevents entry into mitosis in meiotic germline cells.
Domain:
The KH domain and the Qua2 region are involved in RNA binding.
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
The following text describes a protein:
Function:
Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MILLARRLLTLRGLRETVYSRHRALSGPASTDMIRRLPIKKVLCVAEKNDAAKGIAEIMSNGRMRRREGLSKFNKIYEYEYHLFGQNVTVSMTSVSGHLLALEFKAPFQKWHSCNPVMLFDAEVEKYCPDNYVNIKRTLEREVHQCQALVIWTDCDREGENIGFEVIDVCRAVKTSLQVFRARFSEITPNSIRRACETLIEPDINISDAVDVRQELDLRIGASFTRFQTLRLQKIFPTVLADQLISYGSCQFPTLGFVVERFKAIQAFIPETFFKIKVLHHTEDGEVDFSWKRHRLFNHTACLVLYQICMEDPVATVIDVTSKPKSKWRPLPLDTVELEKLASRKLKISAKETMKIAEKLYTQGYISYPRTETNMFPRDLNLTSLVEQQTGDNRWGAFAQGILERGGPTPRNGTKNDQAHPPIHPTKYTSSLQGNEQRLYEFIVRHFLACCSQDAQGHETIVDIDIGQEKFSAHGLMIIARNYLEVYPYDKWNAKVIPVYEPGSRFQPTAIEMVDGETTPPQLLTEADLISLMEKHGIGTDATHADHIETIKSRMYVGLTADQRFLPGELGMGLVEGYDSMGYEMSKPDLRAELEADLKLVSEGKKDKFTVLRHHVEKYKQVFIEAVRKAKKLDEALSAYLGQARELPPQDELQMEGPPVVRKCPQCSRDMVLKKKKDGQGTYLSCVGFPSCRCAVWFPDSVLEVSRDEEVCSTCRPHPVHKLKFKFKRGSLPPLMPLEFVGCIGGCDETLREVLDLKYLRGAGAGAPAANGTSSAGHLRNSQFLNRPRDRPSPAPRPASSKQ
The following text describes a protein:
Function:
Receptor for cAMP which may play a role in prestalk cell differentiation. May act as a negative regulator of cell growth.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MIQILLSTFISFIIIIVSSNDIRSGENDNFNNNKMINNFLTTITTNDTIIIKETESPNDYDFSKEQIESLDKIVYFSSTMGIVGALFIIVSFFLFKAARTFATKMIFFLSLSDLFAAIFYLPYYRDSDIMCNLQGMGLVFFLSSSYLWTMCISISLFMVFFTTIFELNHWFKYFHFICWGIPLFTAIISLIFHAYGKTGSWCFISDPTSIFRLLYYLPLIVVFFINLVVFIAIRWKISQHSNSLVSRVNIIVSFYLIAFSLSQLPTIINSIQNFSDPDNPQFSLFAFQLLLQPLQGFLNCVVYGINEGFINHYVEFFEKYIFRCRCRKSRELKEIESDKTSLLVDYENSDDEEGFDGMDKLIIDDYNRV
The following text describes a protein:
Function:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Sequence:
MDAADYPGASNESGDFSIIRPLSACGSHQQHVSYGEQLCVRLCASNFLLASGYGNSTGSWDGYPHFVNADGLHLSPVICNENQSLLLHASYGFTPEMSYGQYSPVGTPLPSLLVEGPLCASQQVPFPPIYRPLPASPNVPAAVPVIPTELMTLESSRENVHYGTRSGYLIQYGSYGVGNISGIFGSSAVTSPAAYSQPVGILGSYEHRQMVASYTRILLGWRSGSSVGHYPHDGSYQSSKFSSASVPFLGLMTRQDLFLTRARDERETRTQYVFLMSLRVKASGQFCGVAQMAGPVDFESDADFWQQDRWSGQFPVQWHVIKDVPNNGFRHILLQNNDNKPVTHSRDSQEVA
The following text describes a protein:
Function:
Probably acts as an electron carrier.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MAGVFKTVTFLVLVFAAVVVFAEDYDVGDDTEWTRPMDPEFYTTWATGKTFRVGDELEFDFAAGRHDVAVVSEAAFENCEKEKPISHMTVPPVKIMLNTTGPQYFICTVGDHCRFGQKLSITVVAAGATGGATPGAGATPAPGSTPSTGGTTPPTAGGTTTPSGSSGTTTPAGNAASSLGGATFLVAFVSAVVALF
The following text describes a protein:
Function:
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MEHSKQIRILLLNEMEKLEKTLFRLEQGFELQFRLGPTLQGKAVTVYTNYPFPGEAFNREKFRSLDWENPTEREDDSDKYCKVHLQQSGSFQYYFLQGQEKSGGGYIVVDPILRVGADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQALGLSRSCYSLADQLELNPDFSRPNRRYTWDDVGQLVEKLKREWNILCITDVVYNHTAANSKWIHEHPESAYNLVNSPHLKPAWVLDRALWHLSCDVADGKYREKGVPALIENDHHMNCIRKIIWEDIFPRIQLWEFFQVDVQKAVEQFRRLLSQENRRVTKSEPKEHLKIIQDPEFRRLGCAVDMNIALATFIPHDNGPAAIEECCNWFRKRLEELNSEKHHLTSCHQEQAVNCLLGNVFYERLAGHGPKLGPVTRKYPLVTRYFTFPFEEMALSAEESLLHRPDKACFLMAHNGWVMGDDPLRNFAEPGSNVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATHFQGVRLDNCHSTPLHVAEYMLDAARKLQPNLYVVAELFTGSEDLDNIFVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCLRPLMPAIAHALFMDITHDNECPIVHRSAYDALPSTTVVSMACCASGSTRGYDELVPHQISVVAEERFYTKWNPGASPSDTGDVSIHSGIIAARCAINRLHQELGAKGFIQVYVDQVDEDIVAVTRHSPSIHQSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERNTKPYRKDENSINGMPNMTVELRERIQLHESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSSHFKSGSLAVDNSDPILKIPFASIASKLTLAELNQVLYRCESEEQEDGGGCYDIPNWSSLKYAGLQGLMSVLAEIRPKNDLGHPFCENLRSGDWMIDYVSGRLISRSGSIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDVAWKQMSSFVQNGSTFVKHLSLGSVQMCGVGKCPCLPLLSPSLLDVPCRLNEITKEKEQCCASLAAGLPHFSSGLFRCWGRDTFIALRGMLLVTGRYLEARNIILAFACTLRHGLIPNLLGEGTYARYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDSAPLPAGTLDQPLFEVIQEAMQRHMQGIQFRERNAGPQIDRNMKDEGFNITVGVDEETGFVYGGNRFNCGTWMDKMGESDRARNRGIPATPRDGSAVEIVGLCKSAVRWLLELSKKNIFPYHEVRVRRHGKVVAVSYDEWNRKIQNSFEKLFHVSEDPSDPNEKHPNLVHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTAEKAWKALEIAEGKLLGPLGMKTLDPDDMVYCGVYDNALDNDNYNLARGFNYHQGPEWLWPIGYFLRAKLYFSKMMGPETAAKTVFLVKNVLSRHYVHLERSPWKGLPELTNENGQYCPFSCETQAWSMAAVLETLYDL
The following text describes a protein:
Function:
Required for the organization of the mitotic spindle. Maintains the structural integrity of centrosomes during mitosis.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Sequence:
MSGDQSSVISTTRPKEICWIDSQITSIKSLKLHSNLVTLNLHSNHISKIEGLQHLQNLRHLDLSSNQISHIEGLTSLGYLRVLNLSCNRIYLVEGLENLRKLTKLDLSYNFIENVSGLKDLHGNGYSLTTLYLHGNRIASLEHFISSVIGCISLKELTLQMYGEGNHVCNVSGYRDGVLSAMPGLAVLDGYDRTGRAAALNDDLDIPELEEYIQYLQSSSSCEIKTSDSSSSKETRFDVVTPRIDQVLNRFKQRGPLPSDSEQSSVNISPPSQEQARDRQIQGIQPPVDHEVRLGILENLLANFVTSQVRETISWK
The following text describes a protein:
Function:
Involved in determining which thoracic imaginal disk cells will form wings and halteres, perhaps by interacting with other nuclear regulatory proteins. When in combination with scalloped (sd), it acts as a transcriptional activation complex that regulates gene expression in the wing. Binding to sd switches the DNA target selectivity of sd. Required and sufficient for cell proliferation at the dorsal/ventral (D/V) boundary of the wing imaginal disk. Also required for cell proliferation in the wing imaginal disk, mediated via activation of E2f. By interacting with Dhfr, may control genes involved in DNA replication.
Miscellaneous:
MISCELLANEOUS: Loss of vestigial function selectively eliminates wing and haltere formation.
Subcellular Localization:
Nucleus.
Sequence:
MAVSCPEVMYGAYYPYLYGRAGTSRSFYQYERFNQDLYSSSGVNLAASSSASGSSHSPCSPILPPSVSANAAAAVAAAAHNSAAAAVAVAANQASSSGGIGGGGLGGLGGLGGGPASGLLGSNVVPGSSSVGSVGLGMSPVLSGAAGHSLHSSHRTHAHSLAHAHTHPHSHTHTHTHQTKEEDLIVPRSEAEARLVGSQQHQHHNESSCSSGPDSPRHAHSHSHPLHGGGGATGGPSSAGGTGSGGGDGGGTGAIPKNLPALETPMGSGGGGLAGSGQGQAQYLSASCVVFTNYSGDTASQVDEHFSRALNYNNKDSKESSSPMSNRNFPPSFWNSNYVHPIPAPTHHQVSDLYGTATDTGYATDPWVPHAAHYGSYAHAAHAHAAHAHAYHHNMAQYGSLLRLPQQYASHGSRLHHDQQTAHALEYSSYPTMAGLEAQVAQVQESSKDLYWF
The following text describes a protein:
Function:
DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Also has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Subcellular Localization:
Nucleus.
Sequence:
MELQGIVKAFPKRKKTRDDSPKVVPSKVLKDEAGNKQGWMEPITIYVLQAGVGQARAEIFRKQILQNGGSVCSQISPEVTHVIVDEGMDCERAFRLLRLTKLPKGLQLVKASWLSSCISAQQLLDTTGYSLFIPEKYMDEEGHSKKQSQYLDKKTIHPQIENAVLELKAEPQSGANVPFSDVDPSGEQKDKEVISDDEGMEEEDCMVTLGELEALKSGQNPNNTFSGGSPVVPPTGKWVCAQSSESKKMNHNQSITEKLGLLEKAYSVQGDKWRSLGYSKAINALKSYHKPVTSYQEACKIPGIGKKMAEKIMEILESGHLRKLDHISESVSALEVFSNIWGAGVKTAQMWYQQGFRTLDDVRTKASLTRQQAIGLKHYEDFVERMPREEAAEIEQTVREAAQSIQPGLVCVACGSFRRGKSTCGDVDVLVTHPDGHSHQGVFSKLLDCLRKQGFLTDDLVSQEDSGNQKKYLGVCRLPGSDRRHRRLDIIVVPYSEFACSLLYFTGSAHFNRSMRALAKTKGMSLSEHALSRGVVRGHGGLKTVPGLALPTPTEKDVFLLLGLPYREPQERDW
The following text describes a protein:
Function:
May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity).
Subcellular Localization:
Cytoplasm. Membrane; Single-pass membrane protein.
Sequence:
MNSVLGNQTDVAGLFLANSSEALERAVRCCTQASVVTDDGFAEGGPDERSLYIMRVVQIAVMCVLSLTVVFGIFFLGCNLLIKSEGMINFLVKDRRPSKEVEAVVVGPY
The following text describes a protein:
Function:
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MQTFTMVLEEIWTSLFMWFFYALIPCLLTDEVAILPAPQNLSVLSTNMKHLLMWSPVIAPGETVYYSVEYQGEYESLYTSHIWIPSSWCSLTEGPECDVTDDITATVPYNLRVRATLGSQTSAWSILKHPFNRNSTILTRPGMEITKDGFHLVIELEDLGPQFEFLVAYWRREPGAEEHVKMVRSGGIPVHLETMEPGAAYCVKAQTFVKAIGRYSAFSQTECVEVQGEAIPLVLALFAFVGFMLILVVVPLFVWKMGRLLQYSCCPVVVLPDTLKITNSPQKLISCRREEVDACATAVMSPEELLRAWIS
The following text describes a protein:
Function:
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Sequence:
MQIVVASYGARIRAKKGLLIVEGREGRREYPLHQVDEVLLLTGGISISTRALRALLRAGAVVAVFDQRGEPLGIFMKPVGDATGAKRLCQYAAATDGRGLQLAKKWVWLKIRGQLENLKRWRRRLGKYGTYAESISKAINALASAATPREVMEAEAAAAEAYWAAYREITGFPGRDQEGRDPVNAGLNYGYGILKALCFKSILLAGLDPYVGFLHADKSGRPSLVLDFMEQWRPRVDAVVAQLAEELEAENGLLTHKSRLRLAAAVLEEFNATGRPLSAEIHREARSIAKALCTS
The following text describes a protein:
Function:
Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-L-arabinofuranosyl residues in different hemicellulosic homopolysaccharides (branched and debranched arabinans) and heteropolysaccharides (arabinoxylans). It is able to hydrolyze the alpha-(1->5)-glycosidic linkages of linear alpha-(1->5)-L-arabinan (debranched), sugar beet arabinan (branched) and wheat arabinoxylan. Moreover, it displays higher activity towards branched arabinan, a molecule comprising a backbone of alpha-(1->5)-linked L-arabinofuranosyl residues decorated with alpha-(1->2)-, and alpha-(1->3)-linked L-arabinofuranosyl units, than towards debranched arabinan. In addition, arabinoxylan, which has L-arabinofuranose residues attached to the main chain by alpha-(1->2)- and/or alpha-(1->3)-glycosidic linkages, is preferred to linear alpha-(1->5)-L-arabinan.
Subcellular Localization:
Cytoplasm.
Sequence:
MSEHQAVIQTDIAKGTINKNIYGHFAEHLGRGIYEGIWVGTDSDIPNINGIRKDVLEALKQLHIPVLRWPGGCFADEYHWANGVGDRKTMLNTHWGGTIESNEFGTHEFMMLCELLECEPYICGNVGSGTVQEMSEWIEYMTFEEGTPMSDWRKQNGREEPWKLKYFGVGNENWGCGGNMHPEYYADLYRRFQTYVRNYSGNDIYKIAGGANVDDFNWTDVLMKKAAGLMDGLSLHYYTIPGDFWKGKGSATEFTEDEWFITMKKAKYIDELIQKHGTIMDRYDPEQRVGLIIDEWGTWFDPEPGTNPGFLYQQNTIRDALVAASHFHIFHQHCRRVQMANIAQTVNVLQAMILTEGERMLLTPTYHVFNMFKVHQDASLLATETMSADYEWNGETLPQISISASKQAEGDINITICNIDHQNKAEAEIELRGLHKAADHSGVILTAEKMNAHNTFDDPHHVKPESFRQYTLSKNKLKVKLPPMSVVLLTLRADS
The following text describes a protein:
Function:
Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. Required for embryo development.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing OFP5 show kidney-shaped cotyledons, round and curled leaves, small rosette size, late flowering, reduced fertilization and round seeds.
Subcellular Localization:
Nucleus.
Sequence:
MMRWGRKKPVSSSSSSGLSRALPVSWFSKLSGSSDLKPAKEKKQDEKASQNISVKTSLSSTTRRSDIHENSKRFQRVSVEKENSATRSADKESNEKFEEIMSSVRKKVRDFQKETCGFLEVEAMDRDNGTVILTPRIQVNRDKQRCERRDQRLLEQKPKRSEQDAGVKVKKPARRTGTGGYSREDSVILGHTITKPAHQWEKLKEVKLREVKLKADQQRKSLYLKRELNRIGTKENNKVRVFSPRASEKCRVKAIEDLKKAKQRAREHELLIETADGGMENESFAVVKCSSDPQKDFRDSMIEMIMENGINHPEELKELLVCYLRLNTDEYHDMIISVFQQVHNDFNFH
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as non-selective cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHKFSFLLWFSNIHVIILGITAANESSEVEGIIGAILDSSSRIGQEHSVAINLALEDFNIKNNLSFALHVRNSQGDPLLAAIAARDLIDNQKVQAIIGPQTWAETSLVAEVCTQKSIPLLSQADATPEWAMKKWPFLLQSSPSQIMQMKAIAEIVKSWKLYNITMICEDGDSSSIEVLSQLSGALKEVGTELSNVIAILPLVSSSLSQQLEKLREGQCRVLIVHLSFPLALHLFETAKRMDMMGEGNVWITTGTFTSLVYSLNASTISNMQGIIGVKSYIQSLWYQNANFYHRFRKNFSSENFEEFNYEPGIFAAQAYDVAWIVVDAMRKTNQKGGQLLLDKILLSNFTGLSGTIQFTDNKLTPAHTFQIINVIGRSYREIGFWSDGLGFSKSLEQSAFYSSTVKELGKVVNPTCAIRLRIGVPSTSTFKQYVNVIQEDSGNDTSFKFEGFAIDLFEETVKKLQGIYHVEYDYLPFNGTTYDELVKKVYWKEYDAVVGDVAIVSTRYEYVSFTQPYTDPGVVMIVPVKSKTGNRAWLFLKPFTKLMWVLILVIIVYNGFVVWLIERNHCAELKGPILHQTTTMLWLAFCSLFSVNGDRLHSNLSRVATVVWLFVALIITQTYTASLASMLTVEQFEPTVDSIQQLKNSNAMVGYDRGSYLKIYLQDVLGIKAENIKQFDSQKSYADALRNKEIAAAFLDIPEAKIFLAKNCKGFVQAGPTYKIGGYGFVFPKGSPLLHSVNQALLNISENGTLRNLENNMLASEECEDITDPNVETTSLSPASFMVLFILTGGTSTIVLLIYIFSVNHIYPGQRTMWSLMMAVIQSWRSQKRLFSRRVHNVAESPLNSSNISNLPALA