lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in pre-mRNA splicing as component of the spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEREAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHRKHKHRSSSSGGSSSEDEQSQARSQKKMANSFPVLSKVPGYGLQVRDSDRNRGLQGSLGEQRAIKNNSRSRSSSPPRHASKKSTKEERPRDRRSRSPSRRSRSPRPSKPHTSKVNRKERDSPSPKKEAYQRRHASGYTRKLSAEELERKRQEMMENAKWREEERLNTLKRHAREDEREHRLERLDSRSGKFLHRMKLESASTSSLEDRVKRNIHSLQRTSVALEKNFMRR
The following text describes a protein:
Function:
Catalyzes C3-oxidation steps in brassinosteroids biosynthesis. Converts (22S)-22-hydroxycampesterol (22-OHCR) to (22S,24R)-22-hydroxyergost-4-en-3-one (22-hydroxy-campesta-4-en-3-one, 22-OH-4-en-3-one), 6-deoxocathasterone (6-deoxoCT) to (22S,24R)-22-hydroxy-5alpha-ergostan-3-one (22-hydroxy-campesta-3-one, 22-OH-3-one), (22R,23R)-22,23-dihydroxycampesterol (22,23-diOHCR) to (22R,23R)-22,23-dihydroxy-campest-4-en-3-one (22,23-diOH-4-en-3-one), and 6-deoxoteasterone (6-deoxoTE) to 3-dehydro-6-deoxoteasterone (6-deoxo3DT, 6-deoxo-3-DHT).
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MAFTAFLLLLSSIAAGFLLLLRRTRYRRMGLPPGSLGLPLIGETFQLIGAYKTENPEPFIDERVARYGSVFMTHLFGEPTIFSADPETNRFVLQNEGKLFECSYPASICNLLGKHSLLLMKGSLHKRMHSLTMSFANSSIIKDHLMLDIDRLVRFNLDSWSSRVLLMEEAKKITFELTVKQLMSFDPGEWSESLRKEYLLVIEGFFSLPLPLFSTTYRKAIQARRKVAEALTVVVMKRREEEEEGAERKKDMLAALLAADDGFSDEEIVDFLVALLVAGYETTSTIMTLAVKFLTETPLALAQLKEEHEKIRAMKSDSYSLEWSDYKSMPFTQCVVNETLRVANIIGGVFRRAMTDVEIKGYKIPKGWKVFSSFRAVHLDPNHFKDARTFNPWRWQSNSVTTGPSNVFTPFGGGPRLCPGYELARVALSVFLHRLVTGFSWVPAEQDKLVFFPTTRTQKRYPIFVKRRDFAT
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSAAHDIYSVVKPLLIFSKVFGLYPNTVENFETQQLTSPWSNGLDIVWSATIMIFLTFYSIYTMRMGEKPATSTELIVEIGDIIYMSVSLIDAFLLSLFSITKRTKMVQFLQKFANFEKKMQQLDLPLDLANEYTRAKVCVLFAIATAISLIISYVIIDIILFLGNVTFEDIGAEIVAYVYPLVTMMTMVMQFCTLCLLTRQKFRWINLKLDQIRKQWQGKNKTTYYSNKIKFVSPKETTKAITLEKLIYFLEQFRRRHYELCSLTENLNRIFNVQILFTCLNLFITITFTVYFYFISNSDAKIRSPVLYSTYYALNGFINVSALFGLVWAASQTKNEVKSEPKKTLSLKTNIERRSGKLGADVKSPSQFKQFQFPDNAFLVPTFAKQCRIFRLSCVVGAITTYLVIVIQFQYQN
The following text describes a protein:
Function:
Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Mainly cytoplasmic from the 4-cell stage to the morula stage. Becomes nuclear at the blastocyst stage. In ES cells, found in both the nucleus and the cytoplasm.
Sequence:
MTSLDNQGLWSEKDILKLLECMEHNIPSDDSREFKKSQADLNWSKVAFGLFSGEMCKQKWMEISYNLRKFRTLTELVQEAKFSFTKKTHKNKILTEHPDRPKRPLTAYLRFYKEQRAKYCQMYPKYSNAQLTKILAEKYRQLPAEIKQRYIMDFKKEKEDFQKKMRQFKKRHPVSGHPKKSVVPQSHPTKVPTKSQGDIKNVKSLVKTESPRTVSSDMKFQGEPRKPPMNAYHKFHQESWSSPELRHLSFRKRWVEISRRWHQVPENEKEHYSNQVKRLQKQYRVKLDLWLKRLSPEEYAAYKEAKATCGKRKNMSMSGGRSSKFGRTEQSSSEKGLQIKPGEVEELLDPGTDSSGTIQGHHDGAQSSRQDFTDDSEEDDSSTSSDSSSTDEDD
The following text describes a protein:
Function:
Involved in cell division and chromosome segregation. May influence the activity of FtsZ. Binds DNA, but does not seem to function as a transcription factor.
Subcellular Localization:
Cytoplasm, nucleoid.
Sequence:
MSFASETKKELTNLEVKDCCINAELSALIRMNGALSFTNRHLVLDVQTENAAIARRIYTLLKKQYDVSVELLVRKKMRLKKNNVYIVRFSENAKAILEDLKILGENFVFERSISKELVKKRCCKRSYMRGAFLAGGSVNNPETSSYHLEIFSLYKEHNDSLCDLLNEFQLNSKTLERKKGYITYLKEAEKITEFLNVIGAHNSLLRFEDVRIVRDMRNSVNRLVNCETANLNKTIGASLRQVENIKYIDERIGLEALPEKLREIAQLRIDYQEVTLKELGEMVASGKISKSGINHRLRKLDEIAEQLRTGQTVTLK
The following text describes a protein:
Function:
Independently of inflammasome activation, regulates the differentiation of T helper 2 (Th2) cells and has a role in Th2 cell-dependent asthma and tumor growth. During Th2 differentiation, required for optimal IRF4 binding to IL4 promoter and for IRF4-dependent IL4 transcription. Binds to the consensus DNA sequence 5'-GRRGGNRGAG-3'. May also participate in the transcription of IL5, IL13, GATA3, CCR3, CCR4 and MAF.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center. Golgi apparatus membrane. Inflammasome. Mitochondrion. Nucleus.
Sequence:
MAGEESTILLEALEGLTLEDFQEFKKKLPHTDIKGGWNIGRDELEKVTHPSSLISYMGDSYGEGAAMDIAISLFEEMNQRDLAEKILDEKVKEYKQKYTEHVAREFLQYKEANSCLGENLSVRDRYTNLTIARKSWDQHGDEPGDVSSDTVTTQTLFEPSKDGQVPLITVLVGASGMGKTMTIRKVMMEWVEGTLCTQFDYVFCIDCKELSFSKEVSMVDLISKCCPQQRMPAGRILGNPEKILFIFDSFEALGLPLAQPKDELSTDPTEAKPLETTLLSLLRRTVLPESSVLIATRPAALQSLGQCLEGKHYVEILGFSPAAREEYFHRYFGNDNKADVAFRFTRGNEVLYSLCVIPVMSWTVCTVLERELYERNQLLACSKTTTQMIMFYLSWLMKHRVSNAWQNLQQFLHKLCSLAADGIWKHKVLFEEKEIEDQGLNQPQLLSLFLNEKGLEKGTDHVNVYSFSHLHLQELFAAMFYVLEDQDGMVSDSRILAKDVNMLLESYHTSRMDLNVTVRLLFGLVNPKSVEYAGEGIGCRISLQPREDLLRWLQTRPRGTSHPREVMKIEDLDTFHLLFETNEKSFVQSVLGSFTGIALQDVKLTLYDQAALCFCIKQWAGLLSVTLRSCSFHQQHHRQEPAKGLPRQSWQQEELHSPLHPLCQALGHPGSSLQSLRLQWCGLTEGDSGALGTLLATLPSLVHLELGDGALGDDGVRMLCAGLRQPGCQLRVLRLRYTHLTSACCQDLAVALGTSTCLEELDLSFSAGLRDDGVKLLCEGLQHSGCQLRALRLGSCSLTGACCQALVAWLRHSHGLKCLDLSDTELGAGATLLLQHLRHHSCTLQTLGLSTSTLSKDALQELAALRALKPSLKITDLLEHEAPETGAMARLTFQRSVWAGRGAAVRGRKGLPSSRAAPPHSRSLC
The following text describes a protein:
Function:
Beta subunit of the SNF1 kinase complex, which is required for transcriptional, metabolic, and developmental adaptations in response to glucose limitation. Has a structural role, mediating heterotrimer formation, and a regulatory role, defining carbon source-regulated subcellular location and substrate specificity of the SNF1 kinase complex. Promotes the relocalization of the SNF1 kinase complex to the nucleus upon shift to nonfermentable carbon sources.
Miscellaneous:
MISCELLANEOUS: Present with 3590 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Resides in the cytosol during growth on fermentable carbon sources and relocalizes rapidly to the nucleus in response to carbon stress.
Sequence:
MAGDNPENKDASMLDVSDAASNTTINGKHSADSTNEASLAYTFSQMNVDNPNELEPQHPLRHKSSLIFNDDDDDEIPPYSNHAENGSGETFDSDDDIDASSSSSIDSNEGDIHDADMTGNTLQKMDYQPSQQPDSLQNQGFQQQQEQQQGTVEGKKGRAMMFPVDITWQQGGNKVYVTGSFTGWRKMIGLVPVPGQPGLMHVKLQLPPGTHRFRFIVDNELRFSDYLPTATDQMGNFVNYMEVSAPPDWGNEPQQHLAEKKANHVDDSKLSKRPMSARSRIALEIEKEPDDMGDGYTRFHDETPAKPNLEYTQDIPAVFTDPNVMEQYYLTLDQQQNNHQNMAWLTPPQLPPHLENVILNSYSNAQTDNTSGALPIPNHVILNHLATSSIKHNTLCVASIVRYKQKYVTQILYTPLQ
The following text describes a protein:
Function:
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular Localization:
Membrane; Single-pass membrane protein. Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MTIDRTYPIFTVRWLAIHGLAVPTVFFLGSISAMQFIQQ
The following text describes a protein:
Function:
Catalyzes several different glutathione-dependent reactions. Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE. Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB). Catalyzes also the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (LTC4). Involved in oxidative DNA damage induced by ER stress and anticancer agents by activating LTC4 biosynthetic machinery in nonimmune cells.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Sequence:
MAGNSILLAAVSLLSACQQSYFAFQVGRARLKYKIMPPAVSGSPEFDRIFRAQQNSVEFYPAFMITLWMAGWYFNQVFATCLGLLYIYARHQYFWGYSEAANKSCSLRTWARRGRRIPHLGQQSVLAGAALAGPGGHRECRAQGLQTRLPHLPLACLPLSQQGSAWHLVSTAVWKSGEMRPRGAVDWHLDLPLSASCSFAQFTWVKKTKKQGWVNILFLFHVKL
The following text describes a protein:
Function:
Tumor formation by A.tumefaciens involves the transfer and integration of a defined segment (T-DNA) of Ti plasmid DNA into the plant nuclear genome. The virD operon encodes a site-specific endonuclease that cleaves at a unique site within both 24 bp direct repeats flanking the T-DNA.
Sequence:
MPDRAQVIIRIVPGGGTKTLQQIINQLEYLSRKGRLELQRSARHLDIPLPPDQIHELARSWVQETGTYDESQPDEERQQELTTHIIVSFPAGTSQVAAYAASREWAAEMFGSGAGGGRYNYLTAFHIDRDHPHLHVVVNRRELLGHGWLKISRRHPQLNYDALRIKMAEISLRHGIALDASRRAERGITERPITYAQYRRLEREQARQIRFEDADLEQSSPQGDHPEFSQPFDTSPFEASAGGPEDMPRPNNRQNESQVHLQEPAGVSNEAGVLVRVALETERLAQPFVSETILADDIGSGSSRVAEGRVESANRTPDIPRAATEAATHTTHDRQRRAKRPHDDDGGPSGAKRVTLEGIAVGPQANAGEQDGSSGPLVRQAGTSRPSPPTATTRASTATDSLSATAHLQQRRGVLSKRPREDDDGEPSERKRERDERSKDGRGGNRR
The following text describes a protein:
Function:
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
Sequence:
MKKAVILLSGGIDSSTTLIIAKSEGFECYALSFDYGQRHKIEIEAAKKVAKHIGVKEHLIVSFDLRKIGGSALTSKMEIPKEEIEGIPITYVPARNTIFLSFGLAWAEVLQCPNIFIGANIVDYSGYPDCRPEYLQAFERMANLATKISVEGTLKFKINAPLLYLTKSEIIKKGIELGLDYSLTWSCYDPQGDPENPSPCLKCPSCIYRLKGFKEAGIIDPLVK
The following text describes a protein:
Function:
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLQEFVIAAAAGGSNPSAALSQMGFEHLITEMTSSPGDFAVSWVVLITLIAMSAASWYWTVINIFRATRLKSAADRVTTAFWDAPNAQDAIRAMEEQPASEPFSKIALDAAQAAAHHQRAEGSTGGMGESLSRSEFVDRALRQAVTRESTKLQSGMTLLATVGATAPFVGLLGTVWGIYGALIKIGATGSASIDAVAGPVGEALIMTAIGLFVAIPAVFAFNFFSKVNSSVIAKFDTFAHDLHDFFATGSRVR
The following text describes a protein:
Function:
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Sequence:
MSKSLGIPVKLLHEAEGHVVTVEIKSGETYRGTLIEAEDNWNVQLENITHTAKDGKVGQLEHVFIRGSKVRFLIIPDMLKNAPMFKRIDPKTKKQGVSGLGVGRGRAMATRTKGRGPGALGGRGGGFGGRGPGQ
The following text describes a protein:
Function:
May play an important anorexigenic role. Modulates arousal and anxiety as well as increases locomotor activity. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations.
Subcellular Localization:
Secreted.
Sequence:
MIGSLKLSFVLALSLSVMHVLWCYPVLSSKVPGKPDYFLILLSSCPARLEGSDRLAFLKPILEKTSMKRSFRNGVGSGAKKTSFRRAKQ
The following text describes a protein:
Function:
Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MSLVSYPRSESESDIEEETPLASKSFDPTLFQHARRKLSVDSTKKSPKRLKRQVDLQKSSFNDKTFNESDVISNERFKSNDLLELLPAPKNQAELAPKSSKRSDLDLNENYLLPNNSVSDLTSTGSSETVKKSTYSEKSGNVSLFNIVGSESKQASLVDSDQKPYQPILIKPKARANPPKLRNQPENDFISIANHSVHSNAEDINIINEDYIEIGRHRKEKGRIIDVDINKLPKPTQEALPSAPTIKSVAPGRHQLSSLVEMAISQKDNFEAYFEQQRSNKKASSQKYGF
The following text describes a protein:
Function:
Mitochondrial cardiolipin-specific phospholipase which deacylates de novo synthesized cardiolipin (CL). Part of the remodeling process of cardiolipin, which involves deacylation-reacylation of premature cardiolipin.
Subcellular Localization:
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Domain:
The HXXXXD motif is essential for acyltransferase activity.
Sequence:
MSQVKVAVRSEEAANSYTQTFGMSWRQWRQACSEEYAKQCEREVLHTVDFIRENEKDPERLVEVVDSKIYDNDGLVHEVCVSDKATGKANKRSIVYMHGYGAGLGFYFRNMDGLTKGVTKDFNSYFVDWLGMGNSSRPPFDIKGQTASEKVEETERFFTESLETWRIGHGIEKMILVGHSMGGYLSAVYAMQYPERVEKLLLVSPVAIPENPFASNDDAEVYNSVASSAVHAVMDEPPLSNVTNEVLQTQEETTGLEPSRPSKPKNPLPRFITFLWEQNVTPFSLLRLSGPLGPKLMSFWSSRRFSTLPPETFRALHNYCYSIFRLKGSSEYALGNLLAPGAFARRCIMNRLRMLKCRTIFMYGDKDWMDDVAGLEATNRLKEMNIEAEHHIISNAGHHCYLDNPEDFNEIVLKEIRMSLRSFSSISE
The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MRLDDEPENALVVSSSPKTVVASGNVKYKGVVQQQNGHWGAQIYADHKRIWLGTFKSADEAATAYDSASIKLRSFDANSHRNFPWSTITLNEPDFQNCYTTETVLNMIRDGSYQHKFRDFLRIRSQIVASINIGGPKQARGEVNQESDKCFSCTQLFQKELTPSDVGKLNRLVIPKKYAVKYMPFISADQSEKEEGEIVGSVEDVEVVFYDRAMRQWKFRYCYWKSSQSFVFTRGWNSFVKEKNLKEKDVIAFYTCDVPNNVKTLEGQRKNFLMIDVHCFSDNGSVVAEEVSMTVHDSSVQVKKTENLVSSMLEDKETKSEENKGGFMLFGVRIECP
The following text describes a protein:
Function:
Cell wall formation.
Subcellular Localization:
Cytoplasm.
Sequence:
MNDVSSAPSESLTEYFPEDLLHVVRENQPLRETLWLGIGGPARFLAEPVEIDQIEKLYTAAREKQLALRVLGQGSNVLVREAGFDGLVIKLSAPATSGLEIQGQKLVAGAGAKLTHAVIKTVGEGLGGLEHLVGIPGSIGAAVVGNVSAEGRDIGSVVESIEIIDEEGKRKTLTGDEAGFAHRQSTLMGTVVLSVTFNLEPKDVSALTKRMQKLWIHRGQRRPSESNRIAMPFIDPDSISACELINSTGLAGIREGDVSLDSAAPHYLIAHENATSDQCVKLIGRVREQVLMQTGIDLQLNLQIW
The following text describes a protein:
Function:
Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates with differences in substrate specificity between isoform 1 and isoform 2.
Subcellular Localization:
Cytoplasm.
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNAPDYRGQNCMKRHGIPMSHVARQITKEDFTTFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYHGND
The following text describes a protein:
Function:
Probable chimeric globin with a bis-histidyl six-coordinate heme-iron atom through which it could bind dioxygen, carbon monoxide and nitric oxide. Required for sperm flagellum formation and maturation of elongating spermatids, thus playing an essential role in male fertility.
Subcellular Localization:
Cell projection, cilium, flagellum. Note=Expressed within the midpiece and along the whole sperm flagellum. Detected in the annulus of the sperm flagellum in S12 and S15 spermatids and mature sperm.
Domain:
The globin domain is circularly permuted. The globin domain, which normally consists of eight consecutive alpha-helices from A (N-terminal) to H (C-terminal), is circularly permutated and split into two parts. The part containing helices A and B is shifted C-terminally and is separated from the main globin sequence (helices C-H) by a potential calmodulin-binding IQ domain.
Sequence:
MASKQTKKKEVHRINSAHGSDKSKDFYPFGSNVQSGSTEQKKGKFPLWPEWSEADINSEKWDAGKGAKEKDKTGKSPVFHFFEDPEGKIELPPSLKIYSWKRPQDILFSQTPVVVKNEITFDLFSANEHLLCSELMRWIISEIYAVWKIFNGGILSNYFKGTSGEPPLLPWKPWEHIYSLCKAVKGHMPLFNSYGKYVVKLYWMGCWRKITIDDFLPFDEDNNLLLPATTYEFELWPMLLSKAIIKLANIDIHVADRRELGEFTVIHALTGWLPEVISLHPGYMDKVWELLKEILPEFKLSDEASSESKIAVLDSKLKEPGKEGKEGKEIKDGKEVKDVKEFKPESSLTTLKAPEKSDKVPKEKADARDIGKKRSKDGEKEKFKFSLHGSRPSSEVQYSVQSLSDCSSAIQTSHMVVYATFTPLYLFENKIFSLEKMADSAEKLREYGLSHICSHPVLVTRSRSCPLVAPPKPPPLPPWKLIRQKKETVITDEAQELIVKKPERFLEISSPFLNYRMTPFTIPTEMHFVRSLIKKGIPPGSDLPSVSETDETATHSQTDLSQITKATSQGNTASQVILGKGTDEQTDFGLGDAHQSDGLNLEREIVSQTTATQEKSQEELPTTNNSVSKEIWLDFEDFCVCFQNIYIFHKPSSYCLNFQKSEFKFSEERVSYYLFVDSLKPIELLVCFSALVRWGEYGALTKDSPPIEPGLLTAETFSWKSLKPGSLVLKIHTYATKATVVRLPVGRHMLLFNAYSPVGHSIHICSMVSFVIGDEHVVLPNFEPESCRFTEQSLLIMKAIGNVIANFKDKGKLSAALKDLQTAHYPVPFHDKELTAQHFRVFHLSLWRLMKKVQITKPPPNFKFAFRAMVLDLELLNSSLEEVSLVEWLDVKYCMPTSDKEYSAEEVAAAIKIQAMWRGTYVRLLMKARIPDTKENISVADTLQKVWAVLEMNLEQYAVSLLRLMFKSKCKSLESYPCYQDEETKIAFADYTVTYQEQPPNSWFIVFRETFLVHQDMILVPKVYTTLPICILHIVNNDTMEQVPKVFQKVVPYLYTKNKKGYTFVAEAFTGDTYVAASRWKLRLIGSSAPLPCLSRDSPCNSFAIKEIRDYYIPNDKKILFRYSVKVLTPQPATIQVRTSKPDAFIKLQVLENEETMVSSTGKGQAIIPAFHFLKSEKGLSSQSSKHILSFHSASKKEQEVYVKKKAAQGIQKSPKGRAVSAIQDIGLPLVEEETTSTPTREDSSSTPLQNYKYIIQCSVLYNSWPLTESQLTFVQALKDLKKSNTKAYGERHEELINLGSPDSHTISEGQKSSVTSKTTRKGKEKSSEKEKTAKEKQAPRFEPQISTVHPQQEDPNKPYWILRLVTEHNESELFEVKKDTERADEIRAMKQAWETTEPGRAIKASQARLHYLSGFIKKTSDAESPPISESQTKPKEEVETAARGVKEPNSKNSAGSESKEMTQTGSGSAVWKKWQLTKGLRDVAKSTSSESGGVSSPGKEEREQSTRKENIQTGPRTRSPTILETSPRLIRKALEFMDLSQYVRKTDTDPLLQTDELNQQQAMQKAEEIHQFRQHRTRVLSIRNIDQEERLKLKDEVLDMYKEMQDSLDEARQKIFDIREEYRNKLLEAEHLKLETLAAQEAAMKLETEKMTPAPDTQKKKKGKKK
The following text describes a protein:
Function:
Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.
Sequence:
MSSLNPNRANKVDVSSLSPEEQRIFKLYGKLPTQKDVLSKKINERKYFDSGDYAMSRAGRVDSVDAGQVGLQHPNPEKISKLQHNGCGGGSCAPGGSSPPGVQSPIKESSQLSQNN
The following text describes a protein:
Function:
Involved in the biogenesis of the 60S ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MKESNLYRFKDIKPVVSAKELVDVVLSKTQRKTPTEIHKGFKITRIRNFYMRKVKICQELFREKLQNIINDFPKLDDIHPFYSDLANILYDRDHYKLSLGQCSYVSKSLIRICHDYIKLLKFSSSLYKCKMLKISALGRMCKLVKKLQPSLLYLEEVRQNLSRLPSINPHKKTIILSGAPNVGKSSFMNIVSRANVDVQSYSFTTKNLYVGHFDHKLNKYQIIDTPGLLDRAFENRNTIEMTTITALAHINGVILFIIDISEQCGLTIKEQINLFYSIKSVFSNKSIVIGFNKIDKCNMDSLSIDNKLLIKQILDNVKNPIKFSSFSTLTGVGVEQAKITACELLKNDQAESILLDQEQLLNTKLGETKNHLNRTPFIPESVIRERKLRQEKAQSTNNMFDSTNADSITSPCDPTNATEGDPNKQYTMRELKLKKKNKSRQSYLSNRTDDKVLQIDLQNENGGAGVYSVDIRNNYDIKEEYKYDVIPEIYNGKNISDFIDMDIEKKLLELEKEEEELYDKDANIDPLWFKTQKILEKMKLRLKSVRLDAKLKDQNVQIYNKRKKNIEEIEKKLLDLKLDKEKVIKSMTEKARNKNKQPVVKKQKVKKDISKKKQIKDNIYNDENKLSKIFLSTSTELQRKKAYKLNKMAYKKITKGTKGEADRSIPSLKPRHLFSGKRSIGKTSRR
The following text describes a protein:
Function:
Serine protease inhibitor that inhibits trypsin at a molar ratio of 1:1.
Sequence:
SASIPKEISTIFQRDGSEAPVGCCQQRVIVGPCRASFPRWFYNSTADECQFFYFGGCWGNCNNFQSEAACEANDDGGEEKGRCGGSSYI
The following text describes a protein:
Function:
Negatively regulates class switch recombination or isotype switching in splenic B-cells.
Domain:
The BTB domain is important for homodimerization and for its function in negative regulation of class switch recombination.
Sequence:
MSRGYSENNNFLNNNNQMVLDMILYPLIGIPQTINWETIARLVPGLTPKECAKRFDELKSSGSSPVDNQYNSLMAAGESPVETLATYIKSSLLDIHGEFQETPVGHDAVSKTGRHSIASTRNCSSESENCTTHNGGEMTEESEGPNMVIHVCDEAKNLKEDFTCPRDLLISEMKYFAEYLSMDAQRWEEVDISVHCDVHIFNWLIKYIKRNTKENKDCEMPTLEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVATPCNMNCINANLLTRIADLFSHNEVDDLKDKKDKFKSKLFCKKIERLFDPEYLNPDSRSNAATLYRCCLCKKLLTKETERRIPCIPGKINVDRRGNIVYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTINWLTCSRCYQAFLCIEFSHCQYHSETVVYPTAASSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVTLRDQGEGGDLPSCPTARMLDDLHKYRDVIVVPFSKDTVSDVGVGLCDEKGIECDVLLEPNTPWGPKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEVSKKQRKKEKPKKFTRQPKKQVSSPCAQRKEKALEKSASRDVSPFVMSMQKNKWDATRSLRFNQDAQREDDQRRMTEITGHLIKMRLGDLDRVKSKEAKEFAGGIYSRLEAQIKASVPVSARQSSSEKNTRSKSRFGQGRPA
The following text describes a protein:
Function:
Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis.
Subcellular Localization:
Vacuole.
Sequence:
MTLYIFLISLLLLSLLSAVASDDASFQKLPVPGKRSGPESFAFDSTGKAFYTGVSGGKILKYTPDKGFVDFAQITKTSTSSWCKGVFGTALAKKCGRPAGIAFNPKTGDLYVADAPLGLHVIHPAGGVATKIADSVDGKPFKFLDGLDVDPTTGVVYFTSFSSKFSPSEVFIAVGVKDASGKLFKYDPATKAVTVLMEDLSGAAGCAVSSDGSFVLVSEFIKSNIKRYWIKGPKAGSTDDIFSSSVSNPDNIRRIGSTGNFWVASVINKVVMPTDPSAVKIDSNGKVLQTIFLKNEFGNTLLSEANEVDGKLYIGTLTGPFAGVMKL
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of pyridoxal-phosphate (PLP). Can also hydrolyze erythrose-4-phosphate (Ery4P) and fructose-1,6-bis-phosphate (Fru1,6bisP).
Sequence:
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
The following text describes a protein:
Function:
Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINEDPNARLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGALPAVSSPPAPVSPSSPTTHNGELEPSFSPNTESQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREALLAEMGVAVREDGGTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVGQVDMDIKLTGQFIREQHCLFRSIPQPDGEVVVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHPEQARLERERGVPPPPGPPSEPVDWNFAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGDDSDKRSCEESWRLISSLREQLPPTTVQTIVKRCGLPSSGKRRAPRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMRELCRTYGKPDGPGDAWRAVARDVWDTVGEEEGGGAGSGGGSEEGARGAEVEDLRAHIDKLTGILQEVKLQNSSKDRELQALRDRMLRMERVIPLAQDHEDENEEGGEVPWAPPEGSEAAEEAAPSDRMPSARPPSPPLSSWERVSRLMEEDPAFRRGRLRWLKQEQLRLQGLQGSGGRGGGLRRPPARFVPPHDCKLRFPFKSNPQHRESWPGMGSGEAPTPLQPPEEVTPHPATPARRPPSPRRSHHPRRNSLDGGGRSRGAGSAQPEPQHFQPKKHNSYPQPPQPYPAQRPPGPRYPPYTTPPRMRRQRSAPDLKESGAAV
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MNSGGRSLLSSPLFASSSPAFRGGAAAASCSSSSSPSSSSRATVVPMVHDTGGGRASSTACHYSPSLVAAEPEEHVHGRSKDDDDDAAVSLMGEKALLELLLDMALEQHAPGKKLPAEEREESEFDIYLRDDKSHVLYHPEFSSTSVSSSPLSVKSSERSDLGTASAVLTKDVALLAEETDILATQLKASQLYSVDSSKSNEELQSKGQVFVRSTRLLERRSKRRYAPRASIADVSCSADNSKKKEKSKKYGRVLEPDEPFKLFLRDRETTEFLTAKEERHLFSKIQILMKIEEAHRKLEVQCGREPTLAEWAEAVGMSSKELQSSIRTGRRCREKMARSNFRLVIHVARKYEGYGLDIQDLVQDGCSGLMKTFEKFNPSKGCRFPTYAYWWIRQSIKKSIFKNSRLIRLPESVYALLRKVGKARMECIMEGEQPTNANVARRAGITIEKLAKLRAKTRKPRSMQDHVWSDEGVTFQEITEDPNVEPPDLSVDRMMMRQQVRDFLGILSPREKEIIEHRFGIHDGEPKTLHVIGDMFGLSKERIRQLQNRALEKLKRSASLQGFDVYFDLLT
The following text describes a protein:
Function:
Anticoagulant and fibrinolytic protease that modulates blood feeding of ticks on vertebrate hosts. Degrades host fibrinogen and delays fibrin clot formation. Promotes lysis of fibrin clots in the host by activating host plasminogen in the presence of soluble fibrin. Binds Ca(2+). Hydrolyzes serine protease-specific substrates. Required for the formation of a blood pool, an accumulation of blood and tissue fluid developed at the tick's feeding site. Blocks activation of host AGER/RAGE. Reduces AGER/RAGE-dependent production of reactive oxygen species (ROS) in human endothelial cells. Prevents AGER/RAGE-dependent activation of NF-kappa-B and suppresses expression of adhesion molecules, such as VCAM1, ICAM1 and SELE, and secretion of cytokines, such as CSF3/GCSF and TGF-beta, in human endothelial cells. Suppresses RAGE/AGER-mediated migration of mouse peritoneal resident cells. Reduces AGER/RAGE-mediated inflammation in mice tissues.
Miscellaneous:
MISCELLANEOUS: Immunization of mice against the protein induces protective immune response and results in slower tick feeding and smaller blood meals.
Subcellular Localization:
Secreted. Cytoplasm.
Sequence:
MTHRRLLWALCVAALLGVVAAQAGDQQQMQPNEADALRKKWSAVEVVRDLGHIKKDLAKMIELEGAGALSQDELYFYYFRMHDFDNNNKLDGQEMMAAMFHTNHHEEDDEHDGKVPLIIPEQDIASYVDSVLRADKNQDGFISYPELRTSDLTNQI
The following text describes a protein:
Function:
May act as a carbohydrate transporter.
Subcellular Localization:
Vacuole, aleurone grain membrane; Lipid-anchor, GPI-anchor.
Sequence:
MEASRRWPYAAWFMAVLGLVAVFSSSEAYVFYAGGRDGWVVDPAESFNYWAERNRFQVNDTIVFLHDDEVGGSVLQVTEGDFDTCSTGNPVQRLEDVAAGRSVFRFDRSGPFFFISGDEDRCQKGQKLYIIVMAVRPTKPSEAPEPAGAAGPVSSKSWSWQAFPPAGATTPPPLPPSWGSAPEHAQAPGKSSLGGSGGGEMSRSSSLGAPPPTSGAAGLAGVVASVVVGVLGALLMF