lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
Sequence:
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELEGFNITIPHKERIIPYLDYVDEQAINAGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLNINQISLADAEKYLAEFDIVINTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQGAESFKIWTNKDADINSMKTAVLQQLKGE
The following text describes a protein:
Function:
Probable cell surface protease. Required to control the neuronal innervation of pharyngeal pumping.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MYTRFGPPIVFLISCYALILCGTVDALPRAPYFNDDINKTTTTSEDKTVGNTVVEEEKKTYTVGDSEGYQEASRLLQKSLNLSLDPCDDFFEYACRAWVDSHPIPDDLTSYSQFTATREKVLAEMRKLYEDNTSIPTSKSIALIKQIYNTCMDTEKHNAVGARDLLEKIKTYGYWPMVHNEKWRESTFDLTKLLSNTIQSRDVSVFFDFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYLDEKKYEKQMKAYRKYTIGKVRYYTEDAGMAVNESKIESDVDEIIAFEKEWAQILVAEEDRRNYTKLYNVRRFDDLKEYMSIIDWKKLTLSTTPFLVHSYLKTNPSIIISDVEYLQKMNTLLQNTDPRIVTNYILLRWAGSWSQEIGKKYEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKLSYASGSMYVRKYFDANAKNTTLDMITDLQEAFRNMMHANDWMDAETKKYALEKADQMLKQIGYPDFILNDEKLDDWYKGLEGAPEDSFSQLVEKSIQWRNNFYYRRLLEPVNRFEFISSAAVVNAFYSPTRNAIAFPAGILQQPFFDARFPKALNYGGIGAVIGHEITHGFDDTGRQFDNVGNLRDWWDNTTSSKFNERTQCIIEQYADVKLRGTDLRINGKLTQGENIADNGGIKQAFKAYKSYLEKHGGQEARLPQFESLTNEQLFFVGYAQVWCGAKTPETKTLLLLTDPHSPETARVNTVLTNQPEFAEAFKCPAGSPMNPTKRCVVW
The following text describes a protein:
Function:
Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1.
Subcellular Localization:
Mitochondrion.
Sequence:
MMAFLIQRLLRDGRTAGMIPVFRAAHFLRIENWRTVSTLSWQQCKRQVSCTGTSNIIVQSSSMSTSPSSLSPSSREVLSSYQSRQSPFCNYVSRTSKHHSHGRDCYPGGQSQRSLQTCGSALYAGHNKWSKVKYIKGPKDLEKSKAFTRIGIQLKLAVKERGPNPETNSSLAALISLAKSKSMPKATIDSMIKKASTSKQGDSQLTFEVRGPANSSLLVTVLTDNSRRVRQELTQLTSKNGGVFGEQGTAMFAFEKKGVLRVPCDPEDEGSMSLDEAEEVAIDAGAEEVSDETDEDGQSVFMFICDPSDLRSVRDGLAERSLPIQSSGLEYVPQTTIALDDSDLTAVATLIDAFENHEEVLKVFDNVISKD
The following text describes a protein:
Function:
Contributes to K(+)/H(+) antiport activity by supporting proton efflux to control proton extrusion and homeostasis in chloroplasts in a light-dependent manner to modulate photosynthesis. Prevents excessive induction of non-photochemical quenching (NPQ) under continuous-light conditions. Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Sequence:
MAKKKAFTPLFYLAYIVFLPWWISFSVNKCLESWVTNWWNTGQSEIFLNTIQEKSLLEKFIELEELLFLDEMIKEYSETHLEEFGIGIHKETIQLIKMQNENRIHTILHFSTNIICFIILSGYSILGNEKLVILNSWAQEFLYNVSDTVKAFSILLLTDLCIGFHSPRGWELIIGSIYKDFGFVHNDQIISGLVSTFPVILDTIFKYWIFRYLNRLSPSLVVIYHSMND
The following text describes a protein:
Function:
Involved in the biosynthesis of 4-methoxy-2,2'-bipyrrole-5-carbaldehyde (MBC), one of the terminal products involved in the biosynthesis of the red antibiotic prodigiosin (Pig). Catalyzes the conversion of L-proline to L-prolyl-AMP and the transfer of the L-prolyl group to acyl carrier protein PigG.
Sequence:
MTISTPVIIDSLIRHAQRTPEQTALLCGDQHWNYRQLVTRAHVMASALRQAGLSGQAILLNLPKSLDAVAAIYATWLSGNHYIPIDYSQPSSRIERIIAAAAPALIIDTAWLATLDSQPSFDAEQPVGRMVYHNPIAAILYTSGSTGTPKGVQISHEMLGFFIQWAVRDTQLTARDVLSNHASFAFDLSTFDLFASAYVGAATWIIRESEQKDCAALAQGLQRHAVSVWYSVPSILAMLEKSTLLNPTLGQSLRQVIFAGEPYPVTALKRLLPCLPQPCRVSNWYGPTETNVCVAYAIDRARLAMLKQVPIGLPLEGLTAQLEDENGDRHPLTAQLRLSGELLISGPCVTPGYSNVVVPRQAALHPHQCHATGDWVEMTPEGLVFRGRIDDMVKINGYRVELGEIESVLHQHPAIDRAALCVELGDLRQTLIMVISLQTGAVPPGLLELKQFLQQKLPSYMIPNKLVITESLPVNANGKVDRKQLAGVVAV
The following text describes a protein:
Function:
Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing OFP8 show flat, thick and cyan leaves, and enhanced apical dormancy.
Subcellular Localization:
Nucleus.
Sequence:
MEKRMKLRVSRIVRSSLSSCRPRDLYDVVETCAVTSKATSSERFFVTKAKTKTPSRPKSHASSCPRASPIFPPNPFYEESRSFRDLRKKVKTNRKQRSQFGSDPLFASRFKSTGSWYWSCSEEEDEGDKEESEDDDSDTLFSSRSFSSDSSKAESFAVVKKSKDPYEDFRTSMVEMIVERQIFAPAELQQLLQCFLSLNSRQHHKVIVQVFLEIYATLFSP
The following text describes a protein:
Function:
Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases. May also function in Wnt signaling by promoting the rapid degradation of CTNNB1.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Golgi apparatus.
Sequence:
MASSVAPYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYNLKFQPPTLGPEPAARTPEGSPVHGSGPSKDSFGELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDKELLEAQDRVQQTEPQALLAVKSVPVDEDPETEVPTHPEDGTPQPGNSKVEVVFWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAAAGGRAGAPGAPGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGGPEGGGAGSAPIPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHKMTRDPLNLALRRYAGMTLTNLTFGDVANKATLCARRGCMEAIVAQLASDSEELHQVVSSILRNLSWRADINSKKVLREAGSVTALVQCVLRATKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTYKCQSNSLAIIESGGGILRNVSSLVATREDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSARDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAKH
The following text describes a protein:
Function:
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
Sequence:
MAPFTITARDPESRARAGLLQTAHGTVATPVFMPVGTRATVKSLTPHELRDHGASIILGNTYHLYLQPGHELIARHGGLHSFMGWNGPILTDSGGFQVFSLVYGGIADEVKGRRPAHPTRLNDMVTVTEEAVIFKSYLDGSRHVFTPERSIEVQHHLGADIIVCFDELPPFRAGYDYTAQSMARTHRWAERCLIAHQRRDRSALPNPDQLLFGIVHGGIFPDLRRASACYISDMAFDGLCIGGSLGANKTQMYEVVDMTVPYLPDGMARHLLGVGDVDDLLEGVARGIDMFDCVSPTRLGRHGAALIRNRERNWRLNVTNAALRDDRQPLQEGCPCYTCRHFSRAYIHHLYRSKELLGIRLVSLHNVAFLLNLMADIRSALAAGRFGELYTEWLGKPLPVLPSPE
The following text describes a protein:
Function:
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
Subcellular Localization:
Cell outer membrane.
Sequence:
MRRLLIGGLLALLPGAVLRAQPLDWPSLPYDYVAQGESLRDVLANFGANYDASVIVSDKVNDQVSGRFDLESPQAFLQLMASLYNLGWYYDGTVLYVFKTTEMQSRLVRLEQVGEAELKRALTAAGIWEPRFGWRADPSGRLVHVSGPGRYLELVEQTAQVLEQQYTLRSEKTGDLSVEIFPLRYAVAEDRKIEYRDDEIEAPGIASILSRVLSDANVVAVGDEPGKLRPGPQSSHAVVQAEPSLNAVVVRDHKDRLPMYRRLIEALDRPSARIEVGLSIIDINAENLAQLGVDWSAGIRLGNNKSIQIRTTGQDSEEGGGAGNGAVGSLVDSRGLDFLLAKVTLLQSQGQAQIGSRPTLLTQENTQAVLDQSETYYVRVTGERVAELKAITYGTMLKMTPRVVTLGDTPEISLSLHIEDGSQKPNSAGLDKIPTINRTVIDTIARVGHGQSLLIGGIYRDELSQSQRKVPWLGDIPYLGALFRTTADTVRRSVRLFLIEPRLIDDGVGHYLALNNRRDLRGGLLEIDELSNQSLSLRKLLGSARCQALAPARAEQERLRQAGQGSFLTPCRMGAQEGWRVTDGACPKDGAWCVGAERGN
The following text describes a protein:
Function:
Component of the stereocilia rootlet in hair cells of inner ear. Bridges the apical plasma membrane with the lower rootlet and maintains normal distribution of TRIOBP, thereby reinforcing stereocilia insertion points and organizing rootlets for hearing with long-term resilience.
Subcellular Localization:
Cell membrane. Cell projection, stereocilium. Note=Localizes to hair cell stereocilia rootlets. Concentrated to the stereolocilia insertion point.
Sequence:
MKTLRARFKKTELRLSPTDLGSCPPCGPCPIPKPAARGRRQSQDWGKSDERLLQAVENNDAPRVAALIARKGLVPTKLDPEGKSAFHLAAMRGAASCLEVMIAHGSNVMSADGAGYNALHLAAKYGHPQCLKQLLQASCVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAHLNPQDRSGATPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLACEGASPETVEVLLQGGAQPGITDALGQDAAHYGALAGDKLILHLLQEAAQRPSPPSALTEDDSGEASSQNSMSSHGKQGAPKKRKAPPPPASIPMPDDRDAYEEIVRLRQERGRLLQKIRGLEQHKERRQQESPEASSLHILERQVQELQQLLVERQEEKESLGREVESLQSRLSLLENERENTSYDVTTLQDEEGELPDLPGAEVLLSRQLSPSAQEHLASLQEQVAVLTRQNQELMEKVQILENFEKDETQMEVEALAEVIPLALYDSLRAEFDQLRRQHAEALQALRQQETREVPREEGAACGESEVAGATATKNGPTHMELNGSVAPETKVNGAETIDEEAAGDETMEARTMEAEATGAEATGAEATGAKVTETKPTGAEVREMETTEEEANMETKPTGAQATDTETTGVEAMGVEATKTKAEEAEMQAYGVGAGQAEPPVTGTTNMEATGSRATGMESTGVSATGVENPGVEATVPGISAGPILHPGAAEASEKLQVELETRIRGLEEALRQREREAAAELEAALGKCEAAEAEAGRLRERVREAEGSGASGGGGGDTTQLRAALEQAREDLRDRDSRLRELEAASACLDEARASRLLAEEEARGLRAELAQREEARLEQSRELEVLREQLATARATGEQQRTAAAELGRARDAAEARVAELPAACEEARQGLAELREASEALRQSVVPASEHRRLQEEALELRGRAASLEQEVVATGKEAARLRAELERERVCSVALSEHERIVGTLQANVAQLEGQLEELGRRHEKTSAEVFQVQREALFMKSERHAAEAQLATAEQQLRGLRTEAERARQAQSRAQEALDKAKEKDKKITELSKEVFNLKEALKEQPAALATPEVEALRDQVKDLQQQLQEAARDHSSVVALYRSHLLYAIQGQMDEDVQRILSQILQMQRLQAQGR
The following text describes a protein:
Function:
Required for the pachytene checkpoint, the meiotic checkpoint that prevents chromosome segregation when defects in recombination and synaptonemal complex formation occurred. Represses meiotic recombination in the rDNA, probably by excluding the meiosis-specific protein HOP1 from the nucleolar region.
Subcellular Localization:
Nucleus, nucleolus. Chromosome. Note=The majority of the protein localizes to the nucleolar region containing the ribosomal RNA genes (rDNA), a tandem array of 100-150 repeats on chromosome XII. Localization is SIR2-dependent.
Sequence:
MSYIVDLQVRGSSLRVIKCMFREDEQISSLHSGSDSKQNSNKKLGEFLNLLKAVVKRKLESFPKDRLKTSIITGQELMREGQGSIEIKDPPTEAQQHLIRSLAKVLLHQFSSINGKVNTVNEGQDNLFLSLFVKKISIEQQSTSHVSIKLNFHEKINLGQHIDSILDSEETNESDTYHMGSVDEFIIYPFCCLEEQDELKNGSILSTEFDKIDLELDEDDGFEGETLNNCINSVGNFDIPLSKQTLNLVNISYLPGTTFEGQWESLYFGNNIKERLYSYATISLKIARFKQTGDSNQEDITTLITNNKLLLVHGPPGTGKTTLCKALCQKLSVRREFSDGSDTIDTNYKGIIIELSCARIFSKWFGESSKNISIVFKDIEELLKVNEGRGIFICLLIDEVEAIASSRTNLSSRNESTDGIRVVNTLLTQLDRLKKYHNFLALATSNLLDSLDDAFVDRADGVFYVGNPTAEGILHILKVCIEEMITSGIILFHARSTGVKFFNKYQDILRKIAIKCSTVDISGRTIRKLPLMCLSEYFRTFPVDDDEFVLALAMSARKLSAARK
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts closely together with MAB12. Involved in the regulation of embryo patterning and cotyledon organogenesis. May act through transient repression of specific genes such as the ones responsive to auxin.
Subcellular Localization:
Nucleus.
Sequence:
MWTNVFRIGGLHNVSWFQFLPSETELNPGFDRSSRAEQNEVATYLVLSSHLRLQKEGFLTTWTNSFVGPWDPSQGLYNPDEKIKLWLFLPGRHSSISDKAQAAVSKLRVVASGIWVAPGDSEEISVAFSQSLRNCIERALSGISYMRFGDVFSKFSPQSEEYLRRGQPTVEFIFAATEEAVFVHVIISAKNVRTLSSGDAERMLRSSLKNSSYRLPAFRKCLGLAKSEDNRLCYINTSHRPMLFPPVIVSPHGMRGSLTGFCPNDLVKQVYFSSGNLKTSTGYVGLPSHIGRGSRLINGNHCYVEVTLGCCQNRNDNTSQANSTFAVNLPHNQCPEPSVGSKDHRKGQSDLSSVCEKKFIYPAEAVLVPILQSAFAKFSLKRAGDFDCLGASENKSDGFYEKNGYNSSGSSRNSSISSTSSASSGSGWRMTSRTGDLDADADSLTCRQSGLTCNDDRLKMGSKRPRTGMAESFGQVGIENDQIGWDWDADDDDDDREVGMDIKALLSEFGDFGDFFENDALPFGEPPGTAESHVLVFPPDSADVGSSPVDMMDVSDQIVLPVGFSSFESFNPVPPIIDECLIKSQEVLHSSITSVPSNQMSISSTGEFDHLLKAEAMMTFAPEYGAVEAPMSEISSTFFKSPYLPKSHKVESSNSRTSNYVYGATPPTTDSDGAGDMILFGSKSCIGNNAGRTLYHSREHYTQVEGRKGRHDKLPTVISDNSSTKEGVSQSIHSKHSAANAVKVVQGKKTDGISAVVSTLLSSKTLLATDVGSVMFQAFMCRMRHIITSSKHSSPVSLTRLSGNFFLNQLSNEPSTLTDNISARNEIYKKDIPTRIAGDFDGGMLDSHMSAPVGVWRTVSVPKTAKPASSPNIEAGSSLPHSSFSEDSLLSYGQRQPLQDLLDGIALLVQQATSFVDLALDSDCGDGPYGWLALEELWRRELSCGPSAGHAGCGGTLASCHSLDIAGVKLVDPLSAEVFPSSVITLLQSDIKTALKSAFGQSDGPLSVTDWCKGRNQSGDGGSISEGFTAESALSEVNGVNISDDFIIDKYFGKQAVSNAIDGGKGDETAQSQDIYSSELLRPTLFVLPSPAILVGYQDDWLKISTNSLTHWEKAPFEPYALPKSINYAVVCPDIDPLTCAATDFFQQLGTGESTSLSFVKEVMLKHDRNWLGTHLPQSLGNQMEKDVGRLSSSGFVLLDCPQSMKIESNNTSLLGSLSDYFLSLSNGWNVNSYLKSLSKALKGLKLGSGLYTNQKEGSGSPCVVVYIVCPFPDPSAVLRTIVESSIALGSVIQSDRDRRSILNSQVARAFSSSTAVDEASISHIPVLSGFSVPKLVLQVVSVDSIFRITSPSFNELVILKDTAFSVYNKARRISRGMPNDAFFSSSLPSRSSSALTPMNSISGIWKDCGGSRMTGSTHPRDGEIDVSLRTSGWDTSTSWQIPRSGGLSCDPNRNGDFYLNDEIFYLFEPLFILSEPGSVERGVSPTFTSLGSESSKPIPEDGGRGSGPGMNSMEGITSGSSSQGDVSQLEGKAIPSLHCCYGWTEDWRWLVSIWTDARVLQQGCQILQACSSPDNGSFKPRDFVITRIGNFFELEYQEWQKAIYSAGGPEIKKWPIQLRRSAPSGIATNSNGSSLQQQDLSLIQERASSTSTLYSSHSKQSTFVKGSMGQSAGRKQIMGGQTISGTPRGLFQWVHSISFASISLDHSLHFVLPAELVSAGGGQSSTGMSSVNYIEGFTPVKSLGSTAFSYMMIPSPNMRFLHPSPLQLPTCLTAESPPLAHLLHSKGYAIPLSTGFVVSKAVPSMRKDSRINVKEEWPSVLSVSLIDYYGGYDNAHDKILQGIVKQGGGTKETRDFEVESHLILESIAAELHALSWMTVSPAYLDRRTALPFHCDMVLRLRRLLHFADKEVSRIPDKTGV
The following text describes a protein:
Function:
Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MDQRNKTLRDLPWEGERLSFFHDLVEYSFLRTAFVGGILVASLSGLVSPIVVFRRMEFIGDGTAHAVFAGLAAATLIGADHRLIAFATALLFAFAVSLFSRSRISESSAIGILLPFFMAVGVVLFSVSGRYQTDVMGYLFGDVLLVNSTDVAITAVVLALSVILTVVFRWDIKYFIVDEKMARFYGIKTDLIRFLITSFIAITVVTTVKVVGVILTGALLILPGLVSKIFGKSFWSLTTISVIFSTGVFFAGFLTAYTLDLPPGPVIVIIAFVSFLPMLKFS
The following text describes a protein:
Function:
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.
Subcellular Localization:
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Sequence:
MRSLVVFFALAVLTGCQARSLFQADAPQPRWEEMVDRFWQYVSELNTQTDGMVQNIKGSQLSRELDTLITDTMAELSSYSENLQTQMTPYASDAAGQLSKDLQLLAGKLQTDMTDAKERSTQYLQELKTMMEQNADDVKNRVGTYTRKLKKRLNKDTEEIRNTVATYMSEMQSRASQNADAVKDRFQPYMSQAQDGATQKLGAISELMKAQAQEVSEQLEVQAGALKEKLEETAENLRTSLEGRVDELTSLLAPYSQKIREQLQEVMDKIKEATAALPTQA
The following text describes a protein:
Function:
Displays low GTPase activity and exists predominantly in the GTP-bound form.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCDETQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGKRSSKQKRTDRIKGKCVLM
The following text describes a protein:
Function:
Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Also promotes autophagy-dependent peroxisome degradation.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein. Vacuole membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass membrane protein. Note=Is recruited to the preautophagosomal structure during mitophagy and imported into the vacuole along with mitochondria during starvation.
Sequence:
MVLEYQQREGKGSSSKSMPPDSSSTTIHTCSEAQTGEDKGLLDPHLSVLELLSKTGHSPSPMGQNLVTSIDISGNHNVNDSISGSWQAIQPLDLGASFIPERCSSQTTNGSILSSSDTSEEEQELLQAPAADIINIIKQGQEGANVVSPSHPFKQLQKIISLPLPGKEKTPFNEQDDDGDEDEAFEEDSVTITKSLTSSTNSFVMPKLSLTQKNPVFRLLILGRTGSSFYQSIPKEYQSLFELPKYHDSATFPQYTGIVIIFQELREMVSLLNRIVQYSQGKPVIPICQPGQVIQVKNVLKSFLRNKLVKLLFPPVVVTNKRDLKKMFQRLQDLSLEYGEDVNEEDNDDEAIHTKSRSYCRNKKAENSKKKSPKSNKKPKRKKQKFFTSWFTWGISITIGISFGCCVTYFVTAAYEHQTVKSLSLRPSILASLLSLDSSSDTINTPATASPSSTEQFLWFDKGTLQINFHSDGFIMKSLTIIKETWGKMNTFVLHALSKPLKFLENLNKSSEFSIDESNRILALGYILL
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv0299.
Sequence:
MTKEKISVTVDAAVLAAIDADARAAGLNRSEMIEQALRNEHLRVALRDYTAKTVPALDIDAYAQRVYQANRAAGS
The following text describes a protein:
Function:
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
Sequence:
MGILKGKKILITGILNEKSIAFGIAKSMYKQEAELIFVCQNKKIINKIKYLIKSINYNTIFFCDVSHDENIKELFFNIKKVWNNFDGLVHSIAYCPKKQMHEDFVESSSRKSFNICHEISSYSFLSMARECKNMLNKFSSLVTLSYLGSQKIVSNYNMMGLAKSSLEANVRYMANSLGKNNIRVNAISSGPIKTTSSYQIKNFNKIQKIHKLFSLTKNHVSSEEIGNVAAFLCSDLSIGITGSIINVDHGFNLNGINSII
The following text describes a protein:
Function:
Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins.
Subcellular Localization:
Cytoplasm.
Sequence:
MEAERPQEEEDGEQVSCPHQDEQDWPPVNATTRPWRSAPPSPPPPGTRHTALGPCSASLLSLQTELLLDLVAEAQSRRLEEQRATFHIPQNPPSIAPAPLRPLEEREQLYSTILSHQSQRMEAQRSEPPLPPGGQELLELLLRVQGGGRMEEQRSRPPTHTC
The following text describes a protein:
Function:
May be a cell surface adhesion protein.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MARLAILLVLLASSSALSAAQKAATTKAPATAKAAPGPAASSSGGGAADAAPPTDINKALKDEQFSEFKQLLHDTRVDTQINAQLTDSYNGLTIMAPTNTAFDKMKAGVLNGLSPQEQIQMVLYCVLPRFYSLSMLGTLDGKVNTQGSGHDGPYKYDIKRSGNNVNMSTGVNWMLLGSPVSKEFPLAIYPVDKVPLPYELFGPKPPTPAPAPAPAPAKSKTKKKKKSAGIAEPPTADDDTSTSDDQKAAAAPGVGAPTRWVTAALSVLGAAVLGGGLF
The following text describes a protein:
Function:
Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.
Sequence:
MSSARECVWICVDVTARRCEKGVALAIRVGLASPKITLYLAHSVNYIDNIGYMVSCEFNNPQILCVAEKPSIARSVTEILSGNQFTTRQSPNRYTKNFDFHYRLPPSPQLADFTVTSVLGHLTCTDFDADYKGWHNCDPFSLFDAPIHRFVNPDHTGIERNLKAEARRADKLMIWTDCDREGEHIGSEIVSVCRAVKPGIIVLRARFSAIIPAQIHNACQNAGQLDMNQVYAVQARMELDLRIGAALTRCQTMGLQTRFHQLADSLISYGPCQFPTLGFVVDQYDKVKAFVAEAFWYIHVVLERDDSKVEFNWKRHRLFDYHAAFVLHEMCIDEPEATVKDVNIKPTVKWKPLPLTTVELQKSGSRLLHLTPKTVLDIAEKLYQKGLVSYPRTETDQFDRDFDFMGLIEKQMNDSQWGDFATRDLKKGGGFHTPQNGEKKDITPSTNHPTAHANNLTADEKRVYDFITRRYLACCSKNATGKTTTVVIDIAAEEFTATGLVIIERNYLEVYVYDKWNGTLLPDFQIGEKFMPTSCELKEGSTSRPNLLTEADLVGLMDRNGIGTDATIAEHIAKIIDRNYVFKIREGSTQYLVPSTLGIGLVEGYNAIGLDKSLSKPQLRRETEDRMSLICEGSRSKGDVLTQTIDEYREVFIRTRRAFGTIVEQVARYINSAGGQDTNSGDEGEGDGSEGGGDGRGGGGGGGGRGGGGGGGGRGGGGGGGGGGGGGGGNSRGGQGRGTRGTRRGRGTRQTNPGAGPSRGNGRPPTSDDDSDDGDDGPSGGATRDGRGTRGATRAGRATRGTRGSKSTSAAASSRNTTTSASATRAGRSDSTAPLCKCGAQTVERPVVKDGPNKGRLFYGCPKPQSEGSCGFQGWADEGGGGNGGTSGNTSRASAQKRPAGEASLGFPSSRRPKTKESQGPLRCTCDLEAVRRVAGKDGPNKGRAFWVCSKVSKVAQCKFFKWEDELEGGGPAAGSSTTTSTSADKTGCFKCGQQGHWSSECPNPSQGNNNKSIQPSGSNYTCFSCNEQGHLSTTCPNKDGPVGGKGKAGGSTTGQKCFHCNQVGHWANACPSKNDGSAASSSRARGARRGSATRRPRKRASATSSRASSRRKINTPMDTSDDY
The following text describes a protein:
Function:
Histone methyltransferase. Dimethylates 'Lys-36' of histone H3, a specific tag for epigenetic transcriptional activation. Plays a central role in early development and is responsible for all H3 'Lys-36' dimethylation until about the 40-cell stage. Indirectly involved in the global inactivation of the X chromosomes in germline cells, possibly by excluding the mes-2-mes-3-mes-6 repressive Polycomb complex from the autosomes. Not related to transcription elongation. Required for small-RNA-induced H3K27 trimethylation. May suppress sensitivity to RNAi. May regulate the expression of genes required for vulval development.
Subcellular Localization:
Nucleus. Chromosome. Note=Specifically associated with the autosomes and with the distal tip of chromosome X. Colocalizes with methylated 'Lys-4' of histone H3.
Sequence:
MLPSSGDSSKENCAPQDGIVEKEGPNKPFKKKNVKQRNATPQGAGSETSSNAEDKQEEAPILTNAPKDIISMQIQETKAFLSEYEEFVDTDYPKTTFTHVPRKFLSVSPFTPIEADAEGEFLPDADSKCVICHEEKDKTGKSDLITCHGYINGEMDDGKRLLGNIPMFPCRSKFHASCMINYNSGGFHFQYAARLECQARLLCPLHCCNSCNLDHHKQSAYVGDIAECALCLRAFHLTSCYPSGGRDLNVSITIGGKVEKFEMIICPAHYLPGADVQFYNKHKKRKNAVTVVPKADVTMKSHIKACCVIGCEKSSNSKTIMCKTCCRSFHSGCREVETLNGKPIPDDQCESCVCGDPIPQNTLILAKWTDNSFWLALTLDWYKYPTGNRGNINFERLGYTVVQWLIPQENDKEKQPLMSIVPVSDIARLTKNYFSLAKNSTLRNLWEEKYEEQADTALKRCPYVCKTVFGRLRTSVYYKCEPKLEEYHNNEVCNCEGADRCTKLSCQYLADDYECPPSCSKKGVCHNRQVSMGIVSEKIKLAATLCKGYGVFAKGQIEKDEYICEYVGEIIDKAEKKRRLDSVSISRDFQANHYMMELHKGLTVDAARYGNISRYINHSCDPNAASFVTKVFVKKTKEGSLYDTRSYIRAIRTIDDGDEITFSYNMNNEENLPDCECGAENCMGTMGKAKREKPEVADSSEKAAKKNKSSKKKSVKNQNRKSQEAGKNGTASKKSEISPSKPSTSSASSTSFVQQASWPISQNKKNLKKNSNQPVADTGSTLSTSTELNFHEKPQELLSPVSSRSRAASSSTPRAQKSKSRRDDVESEAPPVKRATPSLQTIQETGKAIEFPATKSAITKARALSTQSVPSPHTVEVKVRAISTRGRVQKETKRFEPI
The following text describes a protein:
Function:
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Subcellular Localization:
Chromosome, centromere. Nucleus.
Sequence:
MNAYEKSALYCLVFDYVKSKSSDMFITTSNSHHNDPRAFSKGGMHLKSIPLDKIPPNTLTPIKDLEKLCIEEPCSSRTQAKKPNQLLPTTTALQSTLIQDATCPLEFPNLSVIKPSGGPQENESCRNDPAPLGTLGYFPSNDHDFVLESPAKIFQRMKAFSAQEKRLQTPIKNNRLSDLINCQRDMILTPITNLSVYSRERGSREFRKQSMNTNGKPACSNMYLDSEIPTDILTASPAKIFLLMKEKSLERQKLIHKDATPSQNPKGVDVNTPNTGLNLVSAAENPKEPAKNADFLKVSEECIVSSTNPSPDIALREKGNEADDEMSQQSQLSSLQNETLTPEICKLTSPKKSRENMKTTNEHLNNKTGFMVQPKLMPGIETLKNLGIKGSTICPEMCDILLISPKMHIPRKQKSREEVPAAVLYPDTNRSNSKGEENILLTEWIVTFSGKAGVCLEGKRVRDASGLYWHSNVIVERIQSDKVKTFSGRVYELKGEADKSTMQLEGFPPWFVQKFASGFPEDWKTHVDRVLKESQRAEVKVRIVNHMKSADLKQNSVKDIQERAKHCHSSSKSKELLNLLPSSPTMDSRFNLGDTDQRKTRAYSALRTEPKSNASKTVQSGSADGWDSSNSDTDRENTRRRRKIVSKQHTSKLPNSLSTTNAQTNPIHSNNCTYDLSSEESQDNVSTNVPKERLALVKSRNAVTDRQTKHLSVSEQSHSSLLPRPFSKSTNHTPVLAKNSTYDVSPSESDVHMHSRAIRRSTRNSASGKQRASPLSNDTIVSRSGRLIKPVLKYWCGERVVTDRNLNFVIDEGSTNYLEAETSLVKRKSETKCKEPLTPKELGKNSLRLNKSNLNMEQQQRSETQLKKTIWKEKACSESPNPSQTEESDTEERPRKAQKSPVVLLTPIHSKSQLREKCVKHNVHYESFEETATDTSVFESEIDTRTTLVKNSNGDGIAKSPRIAPVILGDKLSETESSEEDSPSAHISVKRKPRSLSKNSINKCKQDLHTAGDKYGSVEFLNNLRSSPKESLKQKDPHHKRSRTYKAAPQSNDLTSSADSDKEKRPNTRKSAVQKNRRSQRKASRSARRACRSILEDSEETCSSDNDQQQPKHPTARSSLGSIKTPASRLVLSKKIRSLPRNQGSTVSFPKMNHGEEWTEKEVERLYKAVSSLPKHKNGFWVDVAMSVGSRSAEECQEKYLEKQQSKATKAQSKKKPGARNKEVKGSGSEEKPVKITAKVGTLKRKQQMRQFLEQIPKDDHDDIFTATPFQTKRVKLPTFRTSQEDDVFQLSNTDPTTPSSSIFPLAYTPQCEHISPGMLGSINRSNNDKYMYRMQKTTKGALSGWGKLNKKPVGASYATPISRRTAAQGKAHKGCRDTSVIGKLFKSDGPAAPDDDDDDEEEDYYFSNPSP
The following text describes a protein:
Function:
Potential calcium sensor.
Sequence:
MTANHLYCLITMEKSSLFQCKHSSSSFLVDFFLTVFFRWVSFAQSFFSRFCHLPQHQHFVSEKKSKDLEIQSLIEHGNGLCIEDAEMVMQSLGLFTDQESEGLQKRYSSEELSNLFEEKEPSLEEVKQAFDVFDENRDGFLDPIDLQRVLSILGLKQGSNLENCRRMIRSFDGNKDGRIDFHGFVKFMENNFC
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MSNFSSSSSAVATASEVDASIWRAVAGACVQIPPPNSFVYYFPQGHLEHCSFSTAFINSFNFALGRPFIYCQVLSIRFFSNHLSDQVFVKITLQPINTYGPCPVSNAGGDRENNQGDVVLFSKILTPSDANNGGGFSVPRSCADMIFPPLDFAADPPVQNLTLKDTNNNAWEFRHIYRGTPRRHLLTTGWSKFVNAKRLVAGDSAVFMRKQSTDELYIGVRRAQRFGGIEGQNGGEALRAIENAVKGMAFEVLYCPTFGSPDFVVKAEKVCEATRTNWTAGMRVKMAVEADDSSRLTWSSGTIAAVSCPNTGPWCGSPWGLLQMTWDEPESMRNVNRVSPWQVEYLDPTLMLNPNFPPLKKLKLLSYSDMLLSAGEGEIPFPTAEFNSPLFNASIQGARLDPVYIPTTTTTNSQVSKEIPDKNEGEPERETVSTVLSIGSSYSDKDNVSPPSQSSVASATKLVRENSFQLFGQIIQMPQPGEDGACCSNAVSEENPVIDHQLPSPSARVQQQQRFRRPSDKS