lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Negative regulator of the transcriptional complex INO2-INO4 in response to phospholipid precursor availability. When precursors become limiting, OPI1 is retained at the endoplasmic reticulum (ER) and INO2-INO4 activates INO1 and other genes required for phospholipid biosynthesis, whereas abundant precursor availability results in targeting of OPI1 to the nucleus to repress transcription of these genes. Binds directly to phosphatidic acid, which is required for ER targeting and may act as sensing mechanism for precursor availability, as phosphatidic acid becomes rapidly depleted upon phospholipid biosynthesis.
Miscellaneous:
MISCELLANEOUS: Present with 1281 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum. Nucleus. Note=Maintained at the endoplasmic reticulum by SCS2. In response to elevated inositol levels, translocates to the nucleus.
Domain:
The FFAT motif is required for interaction with SCS2 and proper localization of the protein.
Sequence:
MSENQRLGLSEEEVEAAEVLGVLKQSCRQKSQPSEDVSQADKMPASESSTTPLNILDRVSNKIISNVVTFYDEINTNKRPLKSIGRLLDDDDDEHDDYDYNDDEFFTNKRQKLSRAIAKGKDNLKEYKLNMSIESKKRLVTCLHLLKLANKQLSDKISCLQDLVEKEQVHPLHKQDGNARTTTGAGEDETSSDEDDDDEEFFDASEQVNASEQSIVVKMEVVGTVKKVYSLISKFTANSLPEPARSQVRESLLNLPTNWFDSVHSTSLPHHASFHYANCEEQKVEQQQQQQQQQQQQQLLQQQLLQQQQQKRNKDGDDSASPSSSVTANGKVLILAKESLEMVRNVMGVVDSTLGKAEEWVKQKQEVKEMIRERFLQQQQQYRQQQQKDGNYVKPSQDNVDSKD
The following text describes a protein:
Function:
Transcription regulator that plays a central role in embryo development. Required for the maintenance of suspensor morphology, specification of cotyledon identity, progression through the maturation phase and suppression of premature germination. Ectopic expression is sufficient to promote somatic embryogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MDNFLPFPSSNANSVQELSMDPNNNRSHFTTVPTYDHHQAQPHHFLPPFSYPVEQMAAVMNPQPVYLSECYPQIPVTQTGSEFGSLVGNPCLWQERGGFLDPRMTKMARINRKNAMMRSRNNSSPNSSPSELVDSKRQLMMLNLKNNVQISDKKDSYQQSTFDNKKLRVLCEKELKNSDVGSLGRIVLPKRDAEANLPKLSDKEGIVVQMRDVFSMQSWSFKYKFWSNNKSRMYVLENTGEFVKQNGAEIGDFLTIYEDESKNLYFAMNGNSGKQNEGRENESRERNHYEEAMLDYIPRDEEEASIAMLIGNLNDHYPIPNDLMDLTTDLQHHQATSSSMPPEDHAYVGSSDDQVSFNDFEWW
The following text describes a protein:
Function:
Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Subcellular Localization:
Nucleus.
Domain:
The N-terminus is involved in transcriptional activation while the C-terminus is involved in transcriptional repression.
Sequence:
MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGTFPKSTKESRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGGFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEVLSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEEDEEEEDEEEEEEEEEDEEEEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSRNLKEGSKDNPEPLKCKQAWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPLEPDEQVTVEEQKETSEGKTSPTPISIEEEAKEAGEALLPQEENRRQETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEGEEEEEEGGNVEKDPDGAKSQEKEEPEISPEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENEEAFLDLNVQPSHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETGNANIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASKGHVSMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
The following text describes a protein:
Function:
Forms the simplified baseplate, together with the p132 collar protein, the baseplate tube protein p140 and distal tail protein pb9. Closes the tail tube and, upon infection, opens to form a channel thereby anchoring the tube to the outer membrane. These changes allow the tape measure protein pb2 to be expelled and phage DNA to be transferred to the host. Also forms the start of the central straight fiber, which is continued with the straight fiber protein pb4.
Subcellular Localization:
Virion. Note=Component of the tail. Located under the DTP-pb9 hexamer.
Sequence:
MKKILDSAKNYLNTHDKLKTACLIALELPSSSGSAATYIYLTDYFRDVTYNGILYRSGKVKSISSHKQNRQLSIGSLSFTITGTAEDEVLKLVQNGVSFLDRGITIHQAIINEEGNILPVDPDTDGPLLFFRGRITGGGIKDNVNTSGIGTSVITWNCSNQFYDFDRVNGRYTDDASHRGLEVVNGTLQPSNGAKRPEYQEDYGFFHSNKSTTILAKYQVKEERYKLQSKKKLFGLSRSYSLKKYYETVTKEVDLDFNLAAKFIPVVYGVQKIPGIPIFADTELNNPNIVYVVYAFAEGEIDGFLDFYIGDSPMICFDETDSDTRTCFGRKKIVGDTMHRLAAGTSTSQPSVHGQEYKYNDGNGDIRIWTFHGKPDQTAAQVLVDIAKKKGFYLQNQNGNGPEYWDSRYKLLDTAYAIVRFTINENRTEIPEISAEVQGKKVKVYNSDGTIKADKTSLNGIWQLMDYLTSDRYGADITLDQFPLQKVISEAKILDIIDESYQTSWQPYWRYVGWNDPLSENRQIVQLNTILDTSESVFKNVQGILESFGGAINNLSGEYRITVEKYSTNPLRINFLDTYGDLDLSDTTGRNKFNSVQASLVDPALSWKTNSITFYNSKFKEQDKGLDKKLQLSFANITNYYTARSYADRELKKSRYSRTLSFSVPYKFIGIEPNDPIAFTYERYGWKDKFFLVDEVENTRDGKINLVLQEYGEDVFINSEQVDNSGNDIPDISNNVLPPRDFKYTPTPGGVVGAIGKNGELSWLPSLTNNVVYYSIAHSGHVNPYIVQQLENNPNERMIQEIIGEPAGLAIFELRAVDINGRRSSPVTLSVDLNSAKNLSVVSNFRVVNTASGDVTEFVGPDVKLAWDKIPEEEIIPEIYYTLEIYDSQDRMLRSVRIEDVYTYDYLLTYNKADFALLNSGALGINRKLRFRIRAEGENGEQSVGWATI
The following text describes a protein:
Function:
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS to produce anthranilate.
Sequence:
MESLAAATFSPSRLAAHPAPPAAAAAGRSRAVAAGGRRSSRRGSSGLRCSSASATPVINGSAAAKAEEEDRRRFFEAAARGTGKGNLVPVWECIVSDHLTPVLAYRCLVPEDDMDTPSFLFESVEQGLEGTTNVGRYSMVGAHPVMEVVAKENKVTIMDHEKAEVTEKIMDDPMQVPRSIMEGWHPQEIDQLPEAFSGGWVGFFSYDTVRYVEKKKIPFSGAPHDDRNLPDVHLGLYDDVLVFDNVEKKVYVIHWVSVDRHASTEEAYKDGRSRLKRLLSKVHNANVPKLSPGFVKLHTRQFGTPLNKSTMTSDEYKSAVMQAKEHILAGNIFQIVLSQRFERRTYATPFEVYRALRIVNPSPYMAYVQARGCILVASSPEILTKVEKGKVINRPLAGTTRRGKTEHEDKLQEEQLLSDQKQCAEHIMLVDLGRNDVGKVSKSGSVKVEKLMNIERYSHVMHISSTVSGELDDRLESWDALRAALPVGTVSGAPKVKAMELIDQLEVTRRGPYSGGLGGISFDGDMLIALALRTIVFSTAPSHNTMYSYKSSDRRREWVAHLQAGAGIVADSIPDDEQKECENKAAALARAIDLAESAFVDKE
The following text describes a protein:
Function:
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of fgfr2. Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of fgfr2 (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MTVNPDYLVLLFTTTSGASGDKLGSDEKEIVQLVWQVVDLATKKAGQVNELLVKPDHIELSEECQELSGLTDEALTPVDPLEVAIDQLNQRLCAEVDTGAGNTFYLCTDGQLHVRQVLHPEASSKNILLPDCFFSFFDLRKEFKKEFPSEVKLKDLNLQVMADHLNVAVDSSLHAFTAYKVQQMVDIVLALISEPTCHEFTFPEKVNEKFETGTCSKMERVDDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFESEEHRDLALQRHKHHMGGRYIEVYKATGEDFLKIAGGTSNEVASFLSRENQIIVRMRGLPFNATAEQVLQFFSPACPVTDGSEGILFVRFPDGRPTGDAFVLFSCEEHAQNALKKHKDMLGKRYIELFKSTAAEVQQVLNKYSSAPLIPVAPSPILSVVAPPTFVPQTAAVPGVRDCVRLRGLPYDASIQDILVFLGEYGADIKTHGVHMVLNHQGRPSGEAFIQMRSAERAFLAAQRCHKRSMKERYVEVFACSAQEVNIVLMGGTLNRSGLSPPPCLSPPSYTFPHGAPVLPAGAVLPAGAVLPVESAGIYPSQFLLGPRPPPHTTTFYPASNTLYMNYTTYYPSPPGSPSNISYFPTGHTPSAGSVLSAQPTALIRMQGHAHSHAYNNGVKEILSMVQGYQPGNSDAFVTFPSMLSAKQPIGDQTVGGGAYLDLQLL
The following text describes a protein:
Function:
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MRNFKGVNFATLLCSKEETQQLLPDLKEFLSRSRTDFPSSRTDAERRQICDTILRACTQQLTAKLDCPGHLRSILDLAELACDGYLLSTPQRPPLYLERILFILLRNGSTQGSPDTVLRLAQPLHACLVQNSGEAAPQDYEAVTRGSFSLFWKGAEALLERRAAFSTRLNALSFLVLLEDGSVPCEVPHFASPTACRLVAAYQLYDATGQGLDEADADFLYEVLSRHLIRVLVGEGGSSPGPLSPQRALCLLEITLEHCRRLCWNHHHRQAARAVERARNHLEKTSVAPSLQLCQMGVELLEAVEERPGAVAQLLRKAAAVLINSIEAPSPPLRALYDSCQFFLSGLERGIRRHCGLDAILSLFAFLGGYSSLVRHLREVSEASSKQQQCLLQMHFQGFHLFTGIVYDFAQGCQATELAQLVDGCRSAAVWMLEALEGLSGGELADYLSMTASYTSNLAYSFFSQKLYEEACVISEPVCQHLGSATSGACPEVPPEKLHRCFRLHVESLKKLGKQAQGCKMVTLWLAALKPYSLEHMVEPVTFWVRVKMDASRAGDKELQLQTLRDSLSCWDPETQSLLLREELRAYKSVRADTGQERFNIICDLLELSPEETAAGAWARATYLVELAQVLCYHNFTQQTNCSALDAVQEALQLLESVSPEAQEQDRLLDDKAQALLWLYICTLEAKMQEGIERDRRAQAPSNLEEFEVNDLNYEDKLQEDRFLYSSIAFNLAADAAQSKCLDQALTLWKEVLTKGRAPAVRCLQQTAASLQILAAVYQLVAKPLQALETLLLLQIVSKRLQDHAKAASSSCQLTQLLLNLGCPSYAQLYLEEAESSLRSLDQTSDACQLLSLTCALLGSQLCWACQKVTAGVSLLLSVLRDPALQKSSKAWYLLRVQALQVLAFYLSLSSNLLSSALREQLWDQGWQTPETALIDAHKLLRSIIILLMGSDVLSIQKAATESPFLDYGENLVQKWQVLTEVLTCSERLVGRLGRLGNVSEAKAFCLEALKLTTKLQIPRQCALFLVLKGELELARGDIDLCQSDLQQVLFLLESSTEFGVVTQHPDSVKKVHTQKGKHKAQGPCFPPLSEEEPFLKGPALELVDTVLNEPGPIQSSVNSSPVLKTKPPPNPGFLSHLPSCDCLLCASPALSAVCLRWVLVTAGVRLATGHKAQGLDLLQAVLTRCPAATKRFTQSLQASLNHRTTPSCVPSLFDEIMAQVYTHLALEFLNQTSEKSLGKVLASGLKFVATRIQSLEIWRAHLLLVQALAKLAHFSCCTSELFASSWGWHPPLVKSLPVLEPAKIRRQKCSGRGRRRIASVPPPLHNSSQKGLEEEGPPCTPKPPGRARQAGPRVPFTIFEEVHPTKSKLQVPLAPRVHRRAQTRLKVIFSDDSDLEDLVSADTQLVEEPKRRGTASRTRGQTRKGRSLKTDAVVAIESTPGHSSVSGRTRRARKVASRNCEEESPKAPLCVWASQGPEIMRSIPEEEPVDNHLEKSFEILRGSDGEDSASGEKAAAADTGLPVGECEVLRRDSSKAERPVLYSDTEANSDPSPWLPPFSVPAPIDLSTLDSISDSLSIAFRGVSHCPPSGLYAHLCRFLALCLGHRDPYATAFLVAESISITCRHQLLTHLHRQLSKAQKQQESPELAEHLQRLDLKERPGGVPLARIQRLFSFKALGSGCFPQAEKESFQERLALIPSGVTVCVLALATLQPGTLSNTLLLTRLEKDNPPITVKIPTAQNKLPLSAVLKEFDAIQKDQKENSSCTEKRVWWTGRLALDQRMEALITALEEQVLGCWRGLLLPCSADPSLAQEASKLQELLRECGWEYPDSTLLKVILSGARILTSQDVQALACGLCPAQPDRAQVLLSEAVGQVQSQEAPRSQHLVLVLDKDLQKLPWESTPILQAQPVTRLPSFRFLLSYTVTKEAGASSVLSQGVDPQNTFYVLNPHSNLSSTEERFRASFSSETGWKGVIGEVPSLDQVQAALTERDLYIYAGHGAGARFLDGQAVLRLSCRAVALLFGCSSAALAVHGNLEGAGIVLKYIMAGCPLFLGNLWDVTDRDIDRYTEALLQGWLGAGPGAPFLYYASQARQAPRLKYLIGAAPVAYGLPISLQTP
The following text describes a protein:
Function:
Glycosylates adhesin TibA. Specifically adds anomer D-glycero-beta-D-manno-heptose. Cannot use ADP-L-glycero-beta-D-manno-heptose as a sugar donor.
Miscellaneous:
MISCELLANEOUS: Able to functionally replace the autotransporter adhesin heptosyltransferase (AAH) of the AIDA system in fully restoring activity to the AIDA-I adhesin depending on the modification of AIDA-I with heptose residues.
Sequence:
MSTLKNTFFITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGDLLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLTEQGVEATLKKGVSNE
The following text describes a protein:
Function:
Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
Subcellular Localization:
Peroxisome.
Sequence:
MMQKSEIYVSPACLITSNSKDNSLKINNSGILLNGGFIITPVLKDEGDSPIINDANHEFRVILEEIDEHGSSKTIHEVFAMYILTFNSSNNVRKHIKTLFSSSQWNYFPSPNHKINSSITSLEINFLLLKIENSRYSYRTNFNILASVTDDRLRTGEPILVVSTPFANLSPKMFMNSMSSGIISNVVGDDGEVFLIDGRCAPGCQGGTVYRYRPDCYDHVGDLIGLVLIPILWRGKEYVGLAVCCNIQHVLRTLTSFLAAASLNTELTPKLFPSVSSLENSIIVHNPLQHITISPNSSSNINISPSLPSPNISISSRPAFRNVVYVECRNSWGSGIVVDVEGGLVVTCYHVLASWNGDTENENLNCDAAVRIPHLKKRYSAKILNNCSSKNTQILNNNQNTQIHNSSSSSKNQPFYDVAVLKLAVTSPCELYECGMTTLKEVDVCLEFSLGMSVYACGHMLFDKWHSLKPSATCGIISKISYHRHEPVLIQSSSCVHAGMSGGPLLDGEGRIVGIIVSNIRHPIVLAIKNDTSGVCYPHINQHVPMSIIWPLICQYLKTKSDHVFEKLHTDDESLIDTWTLNASAKKPALMCHL
The following text describes a protein:
Function:
Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection.
Subcellular Localization:
Secreted.
Sequence:
MYTQSLLVSLLAGLAAAGPVEVRQLLGGTGSTSKEFSRGGCKDVLFAWARGSTEIGNMGTVVGPPTSDGLKRAFGRDAVATEGIGTNALPGGTDAASERLMATTLTNMASKCPDSVIVAGGYSQGAAVCHRSIEGLPANVKEQIAGVVLYGDTQKLQDRNQIPNFPKEKVKIICQPGDAVCLGTLAVLPAHLTYGVRANEGVQFLTAQIKGTQAKIKARNAKSEAEKLAKEVKRVAKEIVA
The following text describes a protein:
Function:
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments.
Sequence:
MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNSTDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGV
The following text describes a protein:
Function:
May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
Subcellular Localization:
Cytoplasm. Membrane.
Sequence:
ESALSSSVSFRQCSIHSKDPPPDKKHKIEKSSVSSHEFDPTDLVSRTSRSRVDGGKPELCVSAHTGLVQRCVIIQRDDNGFGLTVSGDNPVFVQLVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHVEVVKLIKSGSYVALTVLGRPPGLPQIPLTEVEGDAGPLGHGGSSVTSPHSPGQTAGEHTSSPSDRITAPVPVWEENNIVHNQKVDILQKMLSKEQQDLQISEGEDGAADADQGLSPRGDGAVDSPRPNSTAPSISSGLHSALTDSQCQRDTPCHSPKTAPREGLNSFESPEAEDTPDPDSHSQSSIGSPSSRLASQIIGAEDDYFETEDQQINGQCSCFQSMELLKSRPAHLAAFLHHVVSQFDPAPLLCYLYADLYKQTNSKETRRIFMDFHTFFMDRGANLKVAVPESISTELGGHTERRRPELIPEDLHRQYVQVMQDTLLPDIQKNLEDFRQKRSMGLTVAENDLTKLDTERMRDRVALEKERTCAEHIISKIEDVLLTSQPTEEEKCTTMQYVILSYMKHLGVKVKEPRILEQKRVRIGAFLPKIKVAVGRAMELHGKRLQKQMSQPAPSVPEHPEAGRTRGSQSSEGSDPTHTPSLATSPPHSASGGLSAEPGGRDFDSGAAPFSAAPKHGEGQHPGDSVDGLPRTPNTVFDFNIPGFEQLPEEEREVDRTLEVGTPKAIRRMDTLSGGEVQSEDDQCYEIDAELDPPNWQQLVSREVLAGLTPHEIKRQEVINELFYTERAHLRMLRVLDRVFYQKLSQEAILSLGEIKQIFANLEEILQLHVSISEQMVTIRKKNETSVIDQIGDDLLSWFSGGEEEKIKRAVGTFCSNQPFALELIKTKKKDSRFTAFMQEAESNRLCRRLQLKDIIPVEMQRLTKYPLLLENIAKNTEDAEEREKVKRAGECCRQILNYVNQAVKESENKQRLEDYQRRLDLSSLKQSEYPMISEFKNLDLTKRKMIHEGPLSWKVNKDKTIELYTLLLEDILVLLQKQDERLILKCHSKNLAGTADTKHIFSPIIKLNTVLVRSVATDNKSFFVLSMSDNGAQIYELMAQTVSEQKTWQYLITQRADSMKTKPHNVIPLPQPDSERDDADLISTTAHHKLSKDSDHISTASVQSPEKDVGVASPGMLQTPPSDSAPFEGLKSERSRQGVAVDDEELAAFHFPPSPARAEEALKSCEWKPLLCAELLETHTIKPRQNLVMCVRVAVLRSGAALTLCVSPSVSPDQVSDKTAVKYLCLTFSASAHRYLVLEGDEGAGESSTDDGLLGGPGELGERRGSAGDAGIDLRKLLSPSSLPASAPDFGRQVMTHIRVLQASLHHLKEVETKYNLLCQRLAGSASDTDEHKGTE
The following text describes a protein:
Function:
Essential for the formation of otoliths in the inner ear of developing larvae and for the perception of gravity and acceleration. May be one of the organic components of the ortholiths.
Miscellaneous:
MISCELLANEOUS: Otoliths are structures composed of proteins and calcium carbonate that are found in the fish inner ear in contact with the otic epithelium. They are essential for the perception of gravity and acceleration.
Subcellular Localization:
Secreted. Note=Detected on otoliths and the apical surface of epithelial cells in the otic placode in larvae 24 hours after fertilization.
Sequence:
MLSRTVFVPLILAFVGVSISAPVSNNNGTDNDESAADQRHIFTVQFNVGTPAPADGDSVTTDGKDSAEKNEAPGDSSDTTEKPGTTDGKDSAEQHGVTTDGKDEAEQHGVTTDGQDSAEKRGEADGAPDKPDTQNGTDDTDSDQETDASHHKTGDSDENKDKPSAEDHTDGNHAGKDSTDSKESPDTTDKPEGPDSDSAPDGDSASAEKTDSDHSPDEDANKSSTEADKDDTSDKDSSQTDEKHDSDASDKDEKHEDKDEKSDEKDSSKDSEDKSQEKSDKSDDGSNSEADEQKESVESKDHDSDSQDSDSAEKKEKHDDKDQDSSDSADSKDSDEDKDKDHSEQKDSEDHEHKEKHTKDKEEHKDSDEGKDDEDKSKSDEHDKDESESKEASKSDESEQEEKKDDKSDSDNSSRDSHSDSDSDSHSDSDSDSHSDSHSDSDSDSHSDSDSDSDSDSDSDSDSDSDSNSRDKDEKKDKSSESRDEDSSDSDSKSNSESSETAEEDTNDDKDSSVEKDKTDSSDSASVEANDSDDEHDDDSKDATPSSEDHTAEKTDEDSHDVSDDDDDIDAHDDEAGVEHGTDEASKPHQEPDHHDDTTHGSDDGRKTSMPIS
The following text describes a protein:
Function:
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
Subcellular Localization:
Cytoplasm.
Sequence:
MNILITNDDGIASSGIKALETILQKEHNTYLIAPLRERSATSMALSIYDSMRVERINDNHYIVDGYPADCVNIGLHGEIFPKIDLVLSGINRGVNMGHDVHYSGTVGAARHGAIHKKLSLAVSSGNIAKDYDYIREAEFVRKFINEYSSQLKVGVVYNMNIPSDFISSMENLRVTKLGKRTYEDTYSQKNIIGGIADFYLGGSELGHSTEEGTDFTAFFSGKISLTPLSLDQTDFSILTQLSDSLSKNIS
The following text describes a protein:
Function:
Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling. Modulates red light signaling through its interaction with the phytochrome B photoreceptor.
Subcellular Localization:
Nucleus.
Sequence:
MARDGGVSCLRRSEMMSVGGIGGIESAPLDLDEVHVLAVDDSLVDRIVIERLLRITSCKVTAVDSGWRALEFLGLDNEKASAEFDRLKVDLIITDYCMPGMTGYELLKKIKESSNFREVPVVIMSSENVLTRIDRCLEEGAQDFLLKPVKLADVKRLRSHLTKDVKLSNGNKRKLPEDSSSVNSSLPPPSPPLTISPESSPPLTVSTESSDSSPPLSPVEIFSTSPLSSPIDDEDDDVLTSSSEESPIRRQKMRSPGLD
The following text describes a protein:
Function:
Cell surface proteoglycan.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MHLAFGIIHGAGLLFIITQSALAERWRSEYEDERPVDLESSGDDDFFEDEDMDDVYSGSGSGNFELESGLDLGFRFTTKAPIPPPTVTALKPAPTDHFLPPIQSTWVPPTTQASVVHRHNPWVPPEAPDTPSLPAVPTPTIPSEQATTEATTTETVRTTEVRRLQPVVVVSTEIMATSSSTEKEMFTWEATDEQEATRFNTESGRVWPTEDWRTSLTSEEDSKLEGTEKMTPTLQPQTESWEVTAVTSRDSDFEIPISGGPSGDFEIQEEDVIPQTEPPTSPDLGNELLPPGTAPPDLARGRKPDTGLIDNTIDSGNTLAQMPQKNILERREVLIAVIVGGVVGALFAAFLVMLLIYRMKKKDEGSYALEEPKPASVSYQKPETHEEFYA
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MRESGIGSPRMYATPGGGAAATSGTIFARPAGPRPDGSSSSPQVPAMGRQIPQRVSAFSGYVSSGSSGGSSLDSEAWHACAGPLVCLPLVGDRVVYFPQGHIEQVLASTNQNAADLQIPQYNLPSQIFCRVLNLSLGAYRETDEVYAQMTLVPENEQLDQSLELDEPTASSKAKLSMFSKNLTSSDTSTHGGFSVPRRAAEECFPRLDYQQTPPAQEIIAKDLHGVEWKFRHIYRGQPRRHLLTTGWSVFVSQKKLVAGDTVLFVRGDNGELRIGIRRAVRTQSSVTSSSLLSSHSMQIGVLAAAAHAVSTKTMFTVFYNPRASPAEFVVPYHKYVKSFKMNILIGMRFKMRFETEDSSERSVRYMGTITGIGDIDPARWPGSKWRFLKVGWDEHAASERQERVSPWEIEPFIAPNVTPPVSTKRFRPTMLTDISVSRKSYDNHLRQILQANRNLQTSHKYEADERENFLLKSPTALYSEAKVTSRVTEGHSVPGFPSGLPSPGNEGLPSHRKVDMHQQQLRLCVQQFREQKVPLQFEKPQQPSPTSSFASRQAALSCPLYLQPQHTTDNSFLKLLMSPTLASLQQAPRVEEPLARGNANDSDRECKLFGFSLKPKTALASTVKDDVHKDLESEASGFRKCFTGQNWNQQQQQQQPSRTCTKVHKHGAVGRALDLSKFRGYTQLLEELQHLFGIDESLNGSEWQAVYVDNEGDMLLVGDDPWEEFCSTVRCIRILSPAEIQKLTVQARNSSTEEPSSRLSDQQDSSSPPATSDE
The following text describes a protein:
Function:
Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MQLTFCWLLLLPLVACIHPECKIFQQVMKDEAQCLDKNESLLPGFQGCSGIWDGLSCWPRAAFGEMVTVSCPGFFEEITNIHGFIHRNCTPGNYWSEPFPSYSVACGFKEGITEEPEDEKSYFLAFWHIYTAGYATSLASLITALLIFTIFRKFHCTRNYIHMHLFLSFILRAAAVFTKDAILFSDDSMDHCQMSTVTCKVALTFFQFSILANFFWLLVEGMYLQTLLVLTFVPDKQYAWRFILIGWGAPGVTTLAWIIARIYRQNTGCWDDEEESSAVLWIIKGPILLTVLINFAIFLNVIRILVQKLQSAETGGRHTKHFVRLAKSTLLLIPLFGAHYVVFAFFPESIGMVARLYLELGVGSFQGFLVALLYCFLNGEVQAEFKKRLRKWHYQHYLSFTRKHRSLSRDYSPTNYVTQLSLLDRISPKRSVCPNDLASV
The following text describes a protein:
Function:
Liberates mannose from p-nitrophenyl-alpha-D-mannoside in vitro.
Sequence:
MGTLVASLFVIVILEIVWSYGGVDGAYVKYNTGARVVEGKLNVHLVPHSHDDVGWLKTVDQYYVGSNNSIQGACIENVLDSVVKALARDPNRKFVFAEMAFFQRWWLEQSPETQEQVRKLVDAGQFEFINGGWCMHDEATAHYIDMIDQTTLGHGLIKSQFDKVPRVGWQIDPFGHSAVQAYLLGAEVGFDSLHFARIDYQDRATRKNDKSLEVIWRGSKTFGSSSQIFTNAFPIHYSPPEGFNFEVSNDFEPVQDNTLLYDYNVEKRVNDFISAAMTQANVTRTNHIMWTMGDDFVYQYAESWFKQMDKLIHYVNKDGRVNALYSTPSIYVDAKNAANVSWPLKTDDYLPYADRKDAYWTGYFTSRPALKRYARMLSGYYLAARQLEFLVGRRSSGPSTSRLGDALGLVQHHDALTGTAKQHTTNDYEKRLAIGAFEAAAVVDNALSCLVGKKPGGQCSSPALTFSQCQLLNISFCPATEEDIPDGKSLVVVAYNSLGWNRTDIIRIPVTDSDLVVHDSSGNTIEAQFINLDSVTINLRNFYVKAYLGLSPQQVPKYWLIFQVSLPPLGWSTYFISKAATEGWHLHT
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. PCC1 functions as a dimerization module for the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators (By similarity).
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MDHTLHLHVPFESARLADIAARALAPDPLLRPEELSVSFASDGASLNIKLAAIDARVLRVATNSIFEALKTVVETADELDF
The following text describes a protein:
Function:
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
Sequence:
MIQATGIVAIDPRGVMGALGKLPWSYPEDLRFFAETIRNHPIIMGRKTWESLPDKYKHGRDIVVFSRRMHPPQCIGVSSFAEYGTLSLNHPFLIGGAELFESFFQQNLLKACFVTHIKKEYWGDTFFPITRLSGWKKECICNTEDFSIYYYENNSDQNT
The following text describes a protein:
Function:
Involved in ribosome biogenesis, required for normal progression of rRNA processing. Seems to promote cell proliferation in leaves.
Subcellular Localization:
Nucleus. Nucleus, nucleolus.
Sequence:
MAAPEAPVKYVGICKDSAAFKLMKSMGWEEGEGLGKDKQGIKGYVRVTNKQDTSGVGLDKPNPWAFDTTQFDNILKKLKVQAAPTKTSKNDDDSDKEDESEDDAVKSEPAKLKTVAKVTRPQGRYKRREKGKLVNSYSSKDLEGILVKRTEDPSPAVCDIADSMDIEIISEDQDASIKEQKIEEPSSNWWGFKSGFVSGGLLGAKSGKKKLKASERKMFSENDQENLYNMVQDKATAGKQGLGIKDRPKKIAGVRYEGKKTSFDNSDDDDDDDDDDDEEDEEEDEDESEADDDDKDSVIESSLPAKRKHDEIIEPKIKLKNLCKQIVKKDAGKGGFMKLKQLKSLIDEQAPSVLSEFSSRKDAIAYLKLKLERSGKFVVEGKKISLVSSKK
The following text describes a protein:
Function:
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.
Subcellular Localization:
Nucleus. Endoplasmic reticulum.
Sequence:
MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ