lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as a Ca(2+) sensor which upon Ca(2+) depletion, activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, orai-1. Essential for Ca (2+) and IP3-dependent contractile activity of gonad sheath cells and spermatheca. Essential for fertility. Does not play a role in posterior body wall muscle contraction (pBoc) rhythmicity, intestinal cell oscillatory Ca(2+) signaling or intestinal ER Ca(2+) hemostasis.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Note=Localizes to intracellular puncta in the anterior intestine and reticular structure in the posterior intestine.
Sequence:
MGRVSWIIALYLTINVVIVVNGDRVTRNVEVTAEEEKIRDKLGYEAIRDIHRDMDDDHSGSIDRNESTGFMKEDMQMRGSERTRRENKFHGDDDAITVDDLWEAWFESIERTWTNERLVEWLINDVNLPSIVEAVKAKKIDGKILPRFASPNSDFLNKELGIKSSVYRQKLRLNSLDVVLFGYKDNNNRTKDILLAFLALLLTSLIFLYVRQKQKAQQKVNELSNKLTELKCMETEFEDVQKMLNDERSKRSISDGVVNHTEMENLRVQLEEAERRLEANSNGSQAPLALQPLLRRTCENEMAFLEKQRQDCFKEMKEAIEMVDRLQKKQGSVLSSLKLATGAASTSDQVDSKIFALKSRMEKIHTLTRETQERWLQIESLCGFPLLYLNETEHINRSIASSHFYNKSHEGSSSSGSISNAHSNPNAVNSNFVKKVSPPIPPSQQTANLRFVPTEQSDSIHSEDTSPIVEDVAISRSLTQDLAEADMQSIVSGSTNGSGSVAALKKRKGIFPKLFRRNTSKSSSLGGTSN
The following text describes a protein:
Function:
Component of 1,2-phenylacetyl-CoA epoxidase multicomponent enzyme system which catalyzes the reduction of phenylacetyl-CoA (PA-CoA) to form 1,2-epoxyphenylacetyl-CoA. The subunit E is a reductase with a preference for NADPH and FAD, capable of reducing cytochrome c.
Sequence:
MTTFHSLTVAKVESETRDAVTITFAVPQPLQEAYRFRPGQHLTLKASFDGEELRRCYSICRSYLPGEISVAVKAIEGGRFSRYAREHIRQGMTLEVMVPQGHFGYQPQAERQGRYLAIAAGSGITPMLAIIATTLQTEPESQFTLIYGNRTSQSMMFRQALADLKDKYPQRLQLLCIFSQETLDSDLLHGRIDGEKLQSLGASLINFRLYDEAFICGPAAMMDDAETALKALGMPDKTIHLERFNTPGTRVKRSVNVQSDGQKVTVRQDGRDREIVLNADDESILDAALRQGADLPYACKGGVCATCKCKVLRGKVAMETNYSLEPDELAAGYVLSCQALPLTSDVVVDFDAKGMA
The following text describes a protein:
Function:
May be involved in the folding of the extracellular lipase during its passage through the periplasm.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Sequence:
MKKILLLIPLAFAASLAWFVWLEPSPAPETAPPASPQAGADRAPPAASAGEAVPAPQVMPAKVAPLPTSFRGTSVDGSFSVDASGNLLITRDIRNLFDYFLSAVGEEPLQQSLDRLRAYIAAELQEPARGQALALMQQYIDYKKELVLLERDLPRLADLDALRQREAAVKALRARIFSNEAHVAFFADEETYNQFTLERLAIRQDGKLSAEEKAAAIDRLRASLPEDQQESVLPQLQSELQQQTAALQAAGAGPEAIRQMRQQLVGAEATTRLEQLDRQRSAWKGRLDDYFAEKSRIEGNTGLSEADRRAAVERLAEERFSEQERLRLGALEQMRQAEQR
The following text describes a protein:
Function:
Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MALQTLQSSWVTFRKILSHFPEELSLAFVYGSGVYRQAGPSSDQKNAMLDFVFTVDDPVAWHSKNLKKNWSHYSFLKVLGPKIITSIQNNYGAGVYYNSLIMCNGRLIKYGVISTNVLIEDLLNWNNLYIAGRLQKPVKIISMNEDITLRSALDRNLKSAVTAAFLMLPESFSEEDLFIEIAGLSYSGDFRMVVGEDKTKVLNIVKPNIPHFRELYGSILQENPQVVYKSQQGWLEIDKSPEGQFTQLMTLPKTLQQQINHIMDPPGKNRDVEETLFQVAHDPDCGDVVRLGLSAIVRPSSIRQSTKGIFTAGLKKSVIYSSLKLHKMWKGWLRKTS
The following text describes a protein:
Function:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
Miscellaneous:
MISCELLANEOUS: Present with 538 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSKLVISTSIFQSQVADLLPCNNHQKSQLTYSLINAYDLLQHFDEVLTFPYARKDDLLEFHSKSYIDYLINGRFNKMMAQDVNNPMVESKWSELSELADNWNEKIDYNPSQDLQRFTTRENLYNYYLNHSQALENNMDCINNSEVPTNDKPTDTYILNSETKQYNLEGDCPIFSYLPMYCQVITGATLNLLDHLSPTERLIGINWDGGRHHAFKQRASGFCYINDVVLLIQRLRKAKLNKITYVDFDLHHGDGVEKAFQYSKQIQTISVHLYEPGFFPGTGSLSDSRKDKNVVNIPLKHGCDDNYLELIASKIVNPLIERHEPEALIIECGGDGLLGDRFNEWQLTIRGLSRIIINIMKSYPRAHIFLLGGGGYNDLLMSRFYTYLTWCVTKQFSNLRCGDNNSFQIDPFDVCDGDDSEQFIREHDLVEMYNEENYQYWIYEMEGSSRMKMLRNDNKDRDMVELMKFYEL
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MGSEGEWLTNILPVNGDSLCKSHQEFVGVTHLPDCDWLIRISSGSERDTMSETGEQGYMWPPGSDEEEGHSGFYGAMNGNNDEEDGPTYLHHAGVLLDCQDEESPPGEGEESEESLLGSDKKDSPTSGAPIRPSMSGSRKLTNIIAHLQSLASERESSKQEPPEEPDFHMGESSFAFVHHDIHFDHDEGALASPQGRSHSAEQRLKAFKAIKILQEPDGKEKKYICVECGKTSRYKSAYLRHKRTHTGEKPFSCNDCGKCFRRSSQLVTHQRIHTGEKPYTCLRCGKSFSCNSTLVTHQRTHTGEKPYICMECGKGFIHSSDYNRHHRVHRGEKRYTCKECGKSFSQSSYLVIHQRIHTGEKPFVCNECGKCFSRNSSLVTHQRVHTGERPYTCAECGKSFRQSSHLLIHQRTHTPDSHLALRAMM
The following text describes a protein:
Function:
Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis.
Subcellular Localization:
Early endosome membrane; Peripheral membrane protein. Late endosome membrane.
Sequence:
MAAGAERTDELVREYLLFRGFTQTLRQLDAEIKADKEKGFRADKIVEQLQQFVQAYDLAALREYWSYLERHLFSRLEDVYRPTVGKLKTSLFRYYLVYTIQTSRNDRAQEFFTKQATELQNQAEWKDWFILPFLPSPDTNPAFATYFSRQWADTFIVSLHNFLSVLFQCIFDAECRRTSLVQEENEVLRQKLFALQAESYRLKKEEQQQPEEEEATVHHKLPTYVSNMDRLGDSELGMMCSQRNASLSHSPRVGFLSSLLPQSKKSPSRPGSGPATPPLAARSAPPLGFQASRGKEAVGAAKDGKSPTGPPSGGEAGPGQRRHRRLHDHGKERKELLSKSPLQSAERRAEPGEAEVAAERSAERGEAPGEALTRAPAAGSEGGAARPERPFIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEINIDDDMPRILSLACSPSGASFVCSAAGNQVPGKLLLWDTKTMKQQLRFSLDPEPVAINCTAFNHNGNLLVTGAADGVIRLFDMQRHECAMSWNAHGGEVYSVEFSSDENAVYSIGEDGKFIQWNIHKSGLKVSDCALPAGATGPFVLSGYSGYKQVQVPRGRLFAFDSEGRYVLTCSPTGGVIHKMSGDERVLESCLSLGGHRAPVVTVDWCTAMDCGTCLTASMDGKIKLTTLLAQKA
The following text describes a protein:
Function:
Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification.
Subcellular Localization:
Nucleus. Note=Localization is independent of the other PAF1 complex components.
Sequence:
MSSSESASSDEETKRRAPATSDSDSDSDAGPKPGKPLSTDSSASDSDAEKPQAKPAKKKTLTKRKRRATGSSDDDQVDDDLFADKEDKARWKKLTELEKEQEIFERMEARENAIAREEIAQQLAKKAKKSSEKGVKTEKRRKMNSGGSDAGSPKRKASSDSDSEMDAAFHRPSDINRKHKEKNAMDALKNKRKEIEKKNAKNEALSIDAVFGANSGSSSSSSSSESSRSSSSSRESSPERVSEKDKIVKKDVDGLSELRRARLSRHKLSLMIHAPFFDSTVVGCYVRLGQGQMSGSGSKYRIWKIVGVEESNKVYELEGKKTNKIIKCQNGGSERPFRMQFVSNADFEQIEFDEWLLACKRHGNLPTVDIMDKKKQDIEKAINHKYSDKEVDLMIKEKSKYQTVPRNFAMTKANWSKQKELAQQRGDIREAEQIQTKIDEIERQADELEKERSKSISAIAFINHRNRSKIKDQVLSGQLKIEENSQDDPFTRKKGGMRVVSGSKSRLDGTLSASSSTTNLSDGGKDKSSSLAKPTQPPPSTQIKKKTDISSLHDFDLDIDLGKLKDFSTPESSGNKRPSISSSKGVSLSDYRMRRSGGGDAGSSTSAAPSSAV
The following text describes a protein:
Function:
ARL8 effector that promotes the coupling of endolysosomes to dynein-dynactin for retrograde transport along microtubules. Acts by binding both GTP-bound ARL8 and dynein-dynactin. In nonneuronal cells, promotes concentration of endolysosomes in the juxtanuclear area. In hippocampal neurons, drives retrograde transport of endolysosomes from the axon to the soma. Positive regulator of macroautophagy in dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE-type zinc finger. Positive regulator of osteosclast bone-resorbing activity, possibly by promoting late endosome-lysosome fusion by acting as an adapter protein between RAB7A on late endosomes and LAMP2 on primary lysosomes.
Subcellular Localization:
Cytoplasmic vesicle, autophagosome. Lysosome.
Sequence:
MATAPPPNPQVQKLIKDIEECITELKQQYFTEIQEPITDDNTTLHRFCAKLEILLQTDQKEKSSFLGGKKDYWNYFCDCLAGNKGLNDGIRYVKSQNEVKTNLGRGRAFLRYSLVHQRLADSVQQCVLNGKITSDWYHPRSVLLHHGTSSALVNHFYDLNDIQFDLTPHGHDLDAAWPTFARKMFGSPGQYWRPPSRTPSMSSLGSFSSQPATLSELSSPMMEPLPATPSEEEKYQELQMQLDQSELKERELWKKIKDLEAENEEINKLALDTEDRLSNVRTDLQKKISDLESSLKKSEDYLQEKTKMWKEQENQLEKAKKDAESTVTDLQKRVEVLRTQQESRERVFSEKEQELQERIKSKDTENSELRIELKSVQKELETQKSFDVQKDGSLQGLQQKIASLEAKNVELIATMEGMAKDKDQKAASHFESANKVHEMLNKLTEAEEANVTLKAQKEEMEKKCAGLESQLEERKTKTEKVVAHVKEMRRSLEQQVDSLEKKCENLQKIIEEKSNSEKELQGRLALLQAVTENQEKKTEEISRKADLYKTMVSLKDEESARKLEMAARNYEQKFESVQRSFTTYSSKAESVEGLFSKRLAAMEVANAELRLKAQTSEMSSGESKEKADSLERERTEYEERIQHLDSARKELEDRLLQVETSLSEITGKSQTLQKEKQELDKTVDKLQVQISELEVEKDTLQEEKTQRDKETMELKTKVGDLESEVEGGKEKVSLMERMLDELNMQNDEMRSNMSGNEQKLSQRIKDLSEQISKAESEHSSVKLDLERRLKTSEDNSVGKKNRCKELEDKVSSLEGHCKALIEEKEGVGEELSNNIARVQDLEKEIAEWRIKLETAEIKKLEMTNSMEELKRKVEEEKKERMLVEMKLGTEEAQGSELKNQVKSLEMRWKEEQEGARAVMLELAGLKTSVSRLENKEDELQRRLEEAKRDLRDKDTDVTKLKKKIEDGQSTAKEEKARLQERIATLEGEKGKLVGEIGSLKQQLTGKASNVEQLQDKLKNLEATVGKLGSSELGLRSTLGEKENLIEKKESKIKELTGKLGEMEGKKGALEKEIAELTTTLKARDEDIKELNSHHLTLQEEANAAQAKLEKDMGNLEEKLKRTEEEAANVTKEKGTIEGELQQVRQDLEREEQQRRQLETTVEDMRRLQEENVTQTQVFEERKKKMLQEHEEKMFSMREEMTHLQSQYESTKEEKTDLNKDYEQVSDELEATKEELMKVDQEKTDLKRRVERAESELAEVKVMVDEAVTERNELQGRLFQTSSECLEKLEAAATEKKDLDNHLASVTEEKESLERRASSLQENLEEATSLKQKLEAELERTKDELRTSQSTLEQEVSSLKFQISYDTMQHQGVLKEFEEKQEELKSLQEKSALQEHVISDLEQQILGDKEDHGIALQNVTVEVDELKSSLQSQDKECSSLSSDLQRTKKMLDEERNQTLKIKAELSDARRECEEKERELQEMRTDTMELKTELIKLIREKDQLWQKTDQLEYLQKLRTGERWMEDKEVKKCMKCETDFSIIVRKHHCRLCGRIFCHPCSNHWIMTSHSSSVFLPSTKKSRCCEECFHLHSQLDSRSTDMAGGDTGNTEDNNRVLSDDEDTVDHDERDANFDFVSEEEIAASAGSDAGQSYLGSSESSLTTSLTMSVEEIQGRTDGSCEMSVKAGRSFALPILVEAPGIVLCWEFQTEPKNIGFSVTYKESEAHEDSQVLIPMCKCNSHRQAVQGELIAKRAGVYTLMFDNSYSRFTSKKLTYKLQVKRPVTEASS
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MERVAEACGPSYYTYQVSQHSSDVLQQLNQQRKSGGRFCDVVLRVGEDSFPAHRAVLAACSQYFETVLGAAEGPTPRELEMHTISSKVFGDILDFAYTARIVIRLESFPELMTAAKFLLMRSVIDICQEVIKQSNVQILVPPARPDIMLFRSGSSDIGFPLDMSNGTILGSSGIAGSLGEEEEDSVRPGPAVPSQASLLALGGTPQILPPAYQLGGQSLGSRRGRGRPRKPSSLDSVLFNAVGGLREGGVLPCGLCDKVFTDPLRLRQHEAQHGVTSLQLGYGDLQASRLGENGLGQEEPGMPRKRNRVRKQVSCDLCGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCEKTAEGMSNEVRNDLEKGGGQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMVDHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGGLLSTGPRRPESVPNGAALFHCVRTCGVKDGEKCPHGEQESSDSYGDLSESSDLKSIEKQNANGSYSACELVIPKKTEAEPEKRYPCTECGSFFRSKAYLNKHIQKVHARPLGAGLGDLGPALGPTLGPTLGHSLGPALGPTLGPALGASLGPALGSALASPFSPQQNMSLLESFGFQIVQSAFASSLVDPEGEQQGMSTEGK
The following text describes a protein:
Function:
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity). Promotes the polyubiquitination and proteasome-dependent degradation of RELA/p65, thereby suppressing RELA-mediated NF-kappaB transactivation and negatively regulating inflammatory responses (By similarity). Plays a role in the regulation of spermiation and in male fertility (By similarity).
Miscellaneous:
MISCELLANEOUS: Partially overlaps and is antisense to the RAF1 proto-oncogene.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSTKQITCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHSPHPPSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSPEMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWDFIENRESRHVPNNEDVDMTELGDLFMHLSGVESSEP
The following text describes a protein:
Function:
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
Sequence:
MPAELNGLPAVNGLSNPTPAHPAFDSIPDVIQAFANDEFVIVLDSPSRENEGDLIIAASALTPAKASFMIRYSSGYLCAPLPVSRAAALHLPQMVSDNADPNQTAYAVSVDAADESVTTGISAHDRSLTCRLLADPNSKATSFRRPGHVLPLQARDGGVRVRRGHTEAAVDLCRLAGKQPVGVICELITDGEVVQGRPEFEGGGMMRRDECLSIWQGVGHQGLHH
The following text describes a protein:
Function:
Probably responsible for the transport of L-galactonate from the periplasm across the inner membrane. Is essential for growth on L-galactonate as the sole carbon source.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MEKENITIDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDPRKD
The following text describes a protein:
Function:
Involved in vacuolar transport and vacuole pH homeostasis. Also required for cytokinesis (By similarity).
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MFIISETQRTFASFFIFGLLNNILYVIILSAAIDLVGPSTPKAIVLLADIIPSFSFKVAAPFFIHAVPYIIRLWTLVALSATGMVLISLSPTNVISWKILGITLASLSSGLGEVSFLQLTHYYEENSAIGGFSSGTGGAGLFGSFLFMVLTNVMGFPVWVVLLICAVFPSGFIITYFNLLPLPMHEYQVILQQQQEREEEQEEEEYQQQLQDEARSQNIESIREVKYSVNYISKHVQNTIHKITPLILPYMLPLTTVYISEYVINQGISPTLLFPLKEVPRWLISSYRDIYVVYGFLYQLGVFISRSSVTMGIRIKRLYLLSVLQFINVMITLYQSIYDLPFHSIWWLFLLIFYEGLLGGASYVNTFKSVSEQVSRTKREFSMGCVSISDSLGIVTAGCINWWLELKLCHLQVARGRDWCLKGGSL
The following text describes a protein:
Function:
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrium between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
Subcellular Localization:
Cytoplasm.
Sequence:
MQRKPSQKSATDKLFNHRVNEKITGVSRVRLVSDDGVAIVSFEEALRKAKEENLDLVEVSADQELHVCKIIDYGKYKFELLKKSKEAKKKQHVINVKEIKIRPRIESHDYEIKKKHAQEFLGKGDKVKVSLRFRGREMMHSDLGMKVVYRMIEDLKEHGTAERDPIQDGKQIVVIINPK
The following text describes a protein:
Function:
La protein plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts (By similarity).
Miscellaneous:
MISCELLANEOUS: There are two forms of La, LaA and LaB, in Xenopus.
Subcellular Localization:
Nucleus.
Sequence:
MAENGDKEQKLDSDTKICEQIEYYFGDHNLPRDKFLKQQILLDDGWVPLETMIKFNRLSKLTTDFNTILQALKKSKTELLEINEEKCKIRRSPAKPLPELNDEYKNSLKHKSVYIKGFPTSAILDDVKEWLKDKGPIENIQMRRTLQREFKGSIFIIFNTDDDAKKFLENRNLKYKDNDMTVLSREEYHAKKNEERKLNKSEEKAKSKQVKKEAQKQAEDAERKLVEERVGSLLKFSGDLDNMTSREDLHALFQTHGDIEWIDFSRGAKEGIVLFKMNAKEALDKAKAANSDNLKLKGKDVKWELIEGDTEKEALKKILEGKQESFNKRKGRDGRKFKGKGRGGKGNDSSSRKRTQFQGKKKTFDSSDDEDDMEESESPQKASVKAEESAGTKNGAAAAPGSPKKRSLDDKAEDGPAVKQSKTEVGDQ
The following text describes a protein:
Function:
Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.
Sequence:
MNPKESQNPSAEPLSEREKHLLSIYGKLPHKGLLGAAAKHRTYFDSGDYALAAAHKVTDEGDIQTGTAHPLRESIPHPYAPVPSSGNVAGDANKDSHCRRSSSPE
The following text describes a protein:
Function:
Aminoalkylphosphonate N-acetyltransferase which is able to acetylate a range of aminoalkylphosphonic acids, including aminomethylphosphonate, (S)-1-aminoethylphosphonate and 2-aminoethyl- and 3-aminopropylphosphonate, using acetyl-CoA as acetyl donor. Is required for the utilization of aminomethylphosphonate and (S)-1-aminoethylphosphonate as a phosphate source via the C-P lyase pathway. Is also essential for the detoxification of (S)-1-aminoethylphosphonate, a structural analog of D-alanine that has bacteriocidal properties due to inhibition of cell wall synthesis. Also acts as a N-epsilon-lysine acetyltransferase that catalyzes acetylation of several proteins.
Miscellaneous:
MISCELLANEOUS: The sequence shown is that of strains K12 and B.
Sequence:
MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRDPNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAEEEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Nucleus.
Sequence:
MFFCPFCSTLLLVVPHVEGNALVCATCRYVHSVASASPQVPRNAFGEPILTIQHSFVAHNRQLMDAEEDPAMEAAASSSAAACHTTAAFTPVVKAETSAEGGQITTIPCQNEDNPCQSTKAYFIQIQMRSADEPATVFFKCVECGHQWRQD
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDNPSSDPLPSTLSGEEEKPLALLPPVPRGRRGRPPGAATTSNRTLKSSLPRKRGRPPRSVQETPLTAAVDSSGSSDLLLIDDQGVPYTVPEGSAADGPQGSGSKRAPHFCPVCLRAFPYLSDLERHSISHSELKPHVCKDCGKTFKRSSHLRRHCNIHAGLRPFRCVLCPRRFREAGELAHHHRIHSGERPYQCPSCRVRFTEANTLRRHYKRKHPELVGMPVRLCPPNPRPQPLWDDDEGVPVQEGVQEESPEGKEPAWPISSTSPLSGCTAGGSAGAGHGQEGQDTLVSGGIPAVEGDQKQGPKPLDSDAI
The following text describes a protein:
Function:
Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
Subcellular Localization:
Cytoplasm.
Sequence:
MAALGVEMNVAQDDGETNTAVKVPESVLRRDQARLEEAERRRDVKQSQTVTEEKSDFFTSTFNAEKTQLEEMISSCNDREKAAKTLEEATVKFQQLQKFLNDSVRFLTQYEIRQAQESLQKLQSSITDKREEILPKKKFAFRSRNTSKQQQPTPIQQQTADKPAPGSVGTVVVDAADQCGFSNVDNQVLVRQAEEIQQRDVLLSHLTHCKVRLYGCPSTLHIKNIRSCEIMCGPVSSSVFVDQCTDSTLVFPCQQLRTHNTTATRVYLHVTSRAIIEDCQGVSFAPFTWTYPGILDHFKVAGLSPDRNNWTEVDDFNWLAAGTPSPNWTVIPESERICSWDFVGTAAEQS
The following text describes a protein:
Function:
Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). Participates in ovule development.
Subcellular Localization:
Nucleus.
Sequence:
MRSGECDEEEIQAKQERDQNQNHQVNLNHMLQQQQPSSVSSSRQWTSAFRNPRIVRVSRTFGGKDRHSKVCTVRGLRDRRIRLSVPTAIQLYDLQDRLGLSQPSKVIDWLLEAAKDDVDKLPPLQFPHGFNQMYPNLIFGNSGFGESPSSTTSTTFPGTNLGFLENWDLGGSSRTRARLTDTTTTQRESFDLDKGKWIKNDENSNQDHQGFNTNHQQQFPLTNPYNNTSAYYNLGHLQQSLDQSGNNVTVAISNVAANNNNNLNLHPPSSSAGDGSQLFFGPTPPAMSSLFPTYPSFLGASHHHHVVDGAGHLQLFSSNSNTASQQHMMPGNTSLIRPFHHLMSSNHDTDHHSSDNESDS
The following text describes a protein:
Function:
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
Subcellular Localization:
Cytoplasm.
Sequence:
MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYLESLRNAPIKVYALNEDLIARGLTGQISNDIILIDYTDFVRLTVKHPSQMAW
The following text describes a protein:
Function:
Endonucleolytically cleaves ssRNA generating a 3'-OH and (presumably) a 5'-phosphate group. Cleaves preferentially at U residues, has no activity on dsRNA or dsDNA. Upon expression in E.coli contributes to the degradation of small RNA (sRNA) RhyB.
Sequence:
MIRSMTGFGSASKTQDDLSVSVELKSVNYRFKEVNARLPRPLLYFEDKLKQTILQHIQRGRIELFVSVDSDMLVEKRLEIDWPLLDEFVAAARDMKKRYQLSAEPDVMDFFKLDHVVQVHEEQTQNDKLEALIIDAAEEAVKGLCEMREKEGLLLAKDCLMHIDQLEELVRETELLAADVVSRYRERLYARIKEWTEDVLDESRLVTECAIFADRSDITEEITRLKSHFAQFRDILASGGAVGRKLDFLVQELNREANTIGSKANDHQITKLVVEMKSSIEKIKEQVQNIE
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MPLLDEIPFYWKYIYKIIGIIQFPTEENASNIVPHLWPLPQNCLFIYICVKYYVSINHLKFLGIFYFVDALTSIGTALSLVISITIFIQRSRDLKKLLLQLKEIKIDSVHRKTRSKANHYLRIILIITIFYYFLFIPFESEPLFYTLFFIYPGIILLFDHIFLSDILEIICNEFEQINREIKYQTTSHRIIFKTKKINDEEINDKMVRAEQLSLCHCDLTALTLNICHHFETTIIVAMITSFNYVTSTVYFLIYFLARSYEANLFVLFGNNFAFLSFYVFWLLLILEMFTRTEKEANITGRYIHDIWNKFEANGNMTKKLRHLQLVSIRFLNNKLEFRARNFFRLDWSFCHTMIAAITTYVIILVQFHI
The following text describes a protein:
Function:
Mediates influx of magnesium ions. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MECIKMTKWSWYHVKTSELEKLSSIIPRDVTSYFAQFVKKISSPCENGLYVYTLSPSQTCVYGSFLYDQDKKDAKIQKFLHYFVAHGILITVQEKEEEDFQKLIHNFPMGTKNCNSSDEGLCAISSMFISHYLRKVDYFENNFRNVLWDFYHHNNIAVLERIYHIRHELFMNTHVFRLIQEVLQGLKEAWLEKLTNTLCYKQTHVKLERGLQLVKEYQEELDTMIHLQEVVSSHRGNEIMKALTVLTAVSTPLTALGALWGMNFKYMPELEWKYSYLIALLFIIFTTAGMYMYMRFKGWTGDLLRVKKKKSFFKSN
The following text describes a protein:
Function:
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Kinase partner for the type I interferon receptor IFNAR2. In response to interferon-binding to IFNAR1-IFNAR2 heterodimer, phosphorylates and activates its binding partner IFNAR2, creating docking sites for STAT proteins. Directly phosphorylates STAT proteins but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors.
Subcellular Localization:
Endomembrane system; Peripheral membrane protein.
Sequence:
MAFCAKMRNSKKLEVDIAAKDGLEVHFYLPDKTAIYYPQGEFTAENLCIAAALHCNISPLCHNLFALYNERDQIWYSPNHIFKIDSNVSLNLNYRMRFIFTNWHGTNENEASVWRHYPKKRDGYDKKQNQEGTPLLDASSLDYLFAQGQYELVKCLAPVREPKNDQEVHEIENECLGMAVLAISHYAMKRNIQLHDLPKDIGYKKYIPEMLNRTIKQRNFLTRMRINNVFKNFLKEFNSKTLCDSSVSPHELKVKYLSTMETLTTNYGAEIFETNHLIIKSENEQNGFNNGDYDSMHHYEVSVTGNSGINWRRKPTCTASEKDRKIKWKKTESKSKNSDKKGKSKDEWHCFSYFPEITHIVIKEDTVIINNQDNKSMELKLSTPEEALSFAALIDGYFRLTADAHHYLCSDVAPPLIVNNIKNGCHGPICTEYAINKLRQEGSDEGMYVLRWSCTDFNNILMTVACSKMSQYDSKCLKQYKNFQIEVKKGRYSLLGPDLEFDSLKDLMKHLKGQVLKTDDVSFTLKKCSPPKPREISNLLVATKKALEWQPVYHLSQLSFHRILKEEITQLEHLGRGTRTQIYAGKLNYKDDNDSESYSTEKEIKVILKVLHPSHRDISLAFFETASMMRQVSHKHIVLLHGVCVRDVENIMVEEFVDFGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNILLAREGIDNDCGPFIKLSDPGIPITVLTRQERVERIPWIAPECVEDSRVLSVAADKWSFGTTLWEICFNGEVPLKDRTLAEKERFYGGCFMLVAPSCKELADLINHCMNYDPNRRPFFRAIMREINKLEEQNPDIVSEKSPSAEVDPTLFEKRFLKRVRDLGEGHFGKVELCRYDPEGDNTGELVAVKSLKPGTGGSHIADLKKEIEILRNLYHENIVKYKGICEDGDSGIKLIMEYLPSGSLKEYLPRNVNKINLKQQLKYATQICKGMDYLGSRQYVHRDLAARNVLVENEQIIKIGDFGLTKAIQTDKEYYTVKDDLDSPVFWYAPECLLHCKFYIASDVWSFGVTLYELLTYCNSEYSPMTMFLKMIGPTQGQMTVTRLVRVLEEGKRLPIPANCPKQVYQLMTKCWEQNPSDRTTFQDLIKGFEAIIITL
The following text describes a protein:
Function:
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MPEPKDTAIMFLSRMIRVPKRLLLRGHLIGALLTFLCIICPASGIPTQRDVQQTPKANDQKGNQIKFKDTTNRKPAAHLEANPFIKNSLNWRSDLDNSFICCGLLLNNNTLHITKNGLYFVYTQATFSGNTCLEGDSIFLSHSVVLDSKQFAEKTSLLSAQKTACSEQRKQGMQREKGSLVSKPHATETSVLWSRSIFLGGTFALENGDILYTVTQGQNHLALYPGEAYFGLYAL
The following text describes a protein:
Function:
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization (By similarity). Required for virulence and resistance to cycloheximide.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Sequence:
MELSEGELSHTSSSSSFVPVDQRQLQDAIQIIDENKHFNTGILDYINKTSPADVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMDESNRQQTTKGIWLAYSPVVSTTLGHTTSKSNILVMDVEGTDGRERGEDQDFERKAALFALSTSEVLIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLETHNDHKVLLLIVIRDHVGVTPVESLAKTFTSDLQNMWSSLAKPAELEHLQFADFFDVTFHALNHKVLQPKEFGEGINRLDDRLVVSNELFKPEYHHDVPIDGWTMYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLAKYQHHFKEVDAAPDFEELGALFADLRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLCNTLLEKFEKDLVALKGKDFAVNVKTLSTKLVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAKQQVIELNSIVNKSVKKLSASLSKSIQFELGDPNEETWDNVLQQFKGVYEKFGGDFGLGTSSTQNQQAIEKFKFKSWCQFYDVTHKLISREKLLALLQDRFDDKFRYDENGLPKLYLNEQDLEKTFAVAKQHALQVLPILTFAKLADGSEIVPDYDIFDSKLREQFLGGYDDSDDEEDHCFAEIITEQEKSEVLAKFKKEVDAKYIETKRSIVQHITQIPYYIYLIILVLGWNEFMAIIRNPLFFSLSIVLGATVYVLYYLGLLRPALVVAQRTMDEVIVMAKTKLREVLIDDHEVTGRQLNKMAGSKENIELDDM