lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Subcellular Localization:
Cytoplasm, cytosol. Membrane; Lipid-anchor. Nucleus.
Sequence:
MALYGGGRGRGEDGEKRARVGGIPPTHKISLGALSTNMYCFRRKWVAEVIIWTKLRKSEKRRMGKKRAKGIKKEQKKGRKVIRRKERRGGHTKRIFVRKTRATDLEYQDIMGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLESRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSTSTDDMW
The following text describes a protein:
Function:
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
Subcellular Localization:
Cytoplasm.
Sequence:
MMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQYGPALSSHTPAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVDRLERGVAYYIEASTLTAEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGLALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVKRVLHLPTVAEKTFLVTIGDRTVTGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTLAEMAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEALLAQYGLADCVHYLGQALAGDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDTDPGLNVKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPHPERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG
The following text describes a protein:
Function:
Required for insertion of 4Fe-4S clusters for at least IspG.
Sequence:
MNALAQKTPSPPTLVFTEAAVRKVKGLIDEENNPYLNLRVFITGGGCSGFQYGFTFDEAINSDDLVIEKQLEEEDDDEGGTGQMALVKLLVDPLSLQYLQGAEIDYREDVSGAQFVIRNPNAKTTCGCGSSFAA
The following text describes a protein:
Function:
GTPase that plays an essential role in the late steps of ribosome biogenesis.
Sequence:
MEDTARTDEQRRRVAGWTPVVKTLGDHRLRVAIVGRMNSGKSSLFNLLCEDPTMPAKKNIVKDFNGITRDCVEAHAALDDLHFTVIDTPGLLGGKLVEEAFRTVETADAAIFVTAVDEDVSAEEHDLIQYLAAKKMPTCLLVNKMDLVPEEEEALVLDVYNRLGLGKAVPFSARKREGLDMLSALLEPLYHIHAMRKVENDWDIEDLAMAGDEAAMEEIRDRNCTDRYIRVAIVGRTNSGKTSLVNRLVGYERNRAADESNTTRDPIEIACMYKGRKLKLIDTAGLARQRYRTDREFLSRIHSLSLNEIRYAHVVIVVFDATEGHPNKYDMSILHKVAQEGRPFVLCANKWDAVLDQSATAEAIDFKIKRQVQEVKYSNAVVVSAHTGMNLTLLMDQVLELYDTWNKRVRRSELTKFWRKLEKSVIIPYHVARVGRITQISTRPPTFLLQLQTKKEESQLPKALQEMMKNAITEEFGFRGVPLRLVQEVKDSNPDYI
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
Subcellular Localization:
Cytoplasm. Mitochondrion matrix.
Sequence:
MLRRVVLSSAAARGVARVSQQMRCVSQTSVRFADEKPADEKPADEAAAKPEEPKELSESEALQKQVEELTAKNQDMNDRLLRALADAENVRRISRVDVSNAREFAISKFAKALLDVSDNLKRAHESIDVEALQPEKQLDAIKVLHEGVVMTETQLQKVFREFKINQVGAVGDKFDPNVHDALFEYEDASKEAGSVGQLMKAGYLLNERVIRPAQVGVIKAPKTD
The following text describes a protein:
Function:
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtubule detyronisation regulates mitotic spindle length and postioning. Acts as an angiogenesis inhibitor: inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts.
Subcellular Localization:
Cytoplasm. Secreted. Note=Mainly localizes in the cytoplasm. Some fraction is secreted via a non-canonical secretion system; interaction with SVBP promotes secretion.
Sequence:
MPGGKKVAGGGSSGATPTSAAATAPSGVRRLETSEGTSAQRDEEPEEEGEEDLRDGGVPFFVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARDMRLKIGKGTGPPSPTKDRKKDVSSPQRAQSSPHRRNSRSERRPSGDKKTSEPKAMPDLNGYQIRV
The following text describes a protein:
Function:
May play a role in hematopoietic differentiation or inflammation.
Subcellular Localization:
Secreted. Note=May be targeted through the Golgi via the secretory pathway.
Sequence:
MGRQRRCRWAQPWTLLLLLLGPRLLVTHGWRRKGDKNSENTNILELYLPAVVEYALHVYNMRSQDMNAYKVVRVLRSWLELSEQKEEKGLVFSMELQFARTRCGKFDEDIDNCPFQATPDVNNTITCFFTVDTEPWKTEFQLLNDTCLEGSAE
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MWANPQNLSQVVSPIWTAWKYTGLPVYRFDTVNQKFVSVNTRTYFFGLLILSLVLFLCVQNVFTDDGFVVVNDGINFSQMLILFISNSCTVFLSYRKRKDFSRILSELDLTETRIEKLTKKRISYHADVRKVVLIILATKYGLIATGCLVDCANLVGEEVNMILYYILFSIYFHFEIIIVTYLVVLKRQYREINGYLKSLRVKVLTNYEIREILKVYSVLRQNFTMIKKGFDSIIVVKVIRDIIVTTTGIFFVLETYNVGNTQFLFTTLTNVIWGTTTALTNFLIPVILHDISDQDKFLKLHVAELLHNIKKHLKTFDNQLVLFTIKTVFSKIDLKISGLFSYDCTYITWMIASVTTYVVYLVQFEEPR
The following text describes a protein:
Function:
Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth. Can phosphorylate ROPGEF1 in vitro.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The protein kinase domain may be catalytically impaired due to the lack of the conserved Asp active site at position 486, which is replaced by a Asn residue.
Sequence:
MTAVLFLCFLLICFSFTPSLQNVSESEPLVRFKRSVNITKGDLNSWRTGTDPCNGKWFGIYCQKGQTVSGIHVTRLGLSGTINIEDLKDLPNLRTIRLDNNLLSGPLPPFFKLPGLKSLLLSNNSFSGEIADDFFKETPQLKRVFLDNNRLSGKIPASLMQLAGLEELHMQGNQFTGEIPPLTDGNKVLKSLDLSNNDLEGEIPITISDRKNLEMKFEGNQRLCGSPLNIECDEKPSSTGSGNEKNNTAKAIFMVILFLLIFLFVVAIITRWKKKRQPEFRMLGKDHLSDQESVEVRVPDSIKKPIDSSKKRSNAEGSSKKGSSHNGKGAGGGPGSGMGDIIMVNSEKGSFGLPDLMKAAAEVLGNGSLGSAYKAVMANGLSVVVKRIRDMNKLAREAFDTEMQRFGKLRHPNVLTPLAYHYRREEKLVVSEYMPKSSLLYVLHGDRGVYHSELTWATRLKIIQGVARGMDFLHEEFASYDLPHGNLKSSNVLLSETYEPLISDYAFLPLLQPNNASQALFAFKSPEFVQNQQVSPKSDVYCLGIIVLEVMTGKFPSQYLNTGKGGTDIVEWVQSSIAQHKEEELIDPEIASNTDSIKQMVELLRIGAACIASNPNERQNMKEIVRRIERVTL
The following text describes a protein:
Function:
Proteolytically removes the C-terminal three residues of farnesylated proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MFEFLQQNTIPYQSIILALSGGVFAFEQYLNIRQLPHLKLKVPPPSIAPYLVAADGPKTEADKKDTPKGEDGAPTEKPSTQETFMKSQAYALDKVKFSMIAGVIDQVETWALLSPFVAVYFGSDGAKPASGIASLWHLAIDLCQRWSRLAPAFLNIGTGEIATSLFFVSLLSLTGMITSIPSSLYKTFVLEEKHGFNKQTLGLWITDYIKTTILSAVFGLPLIAAFLWIVRWAGEAFVQYVMMLVMGLVLFMYVGYPYLIAPLFNKFRHLSEFPEYEEVKTRTEALAKRINFPLGRLWVIDGSKRSAHSNAFFFGLPGLTKHIVLYDTLLKQSTAAEVEAVLAHELGHWKLNHTVLLLGSSQIQIGLSLSTFRFFIWNAALFYSFGVPALAGGADKYPLIIGFILAQSLFTPLNSLLSFTSNALSRKLEFQADQFAADLGGDYAKDLKWALVRISAENKATTSCDWLYSAFHHSHPTLPERLGRLSTLTNKKK
The following text describes a protein:
Function:
Involved in the catabolism of quinolinic acid (QA).
Sequence:
MPEFKNLLPANGAWKHDITNWLQEDVPAFDYGGYVVGSATKTATLLCKQKGVLAGVPFADEVFRQCNLECQWLFVEGDELDPSATGKIPVAKVTGEARNILLAERTALNILSRCSGIASASRNIIASARAAGYRGTVAGTRKTTPGLRRLEKYAMLVGGCDTHRYDLSSMVMLKDNHIWATGSITRAVQDARAACGFTIKIEVECQSEAEADEAIAAGADVIMLDNFTGTSLRATAQRLKERWAGKKNFLLECSGGLRIDNLSEYLCQDIDIYSTSSIHQGTPVVDFSLKIDH
The following text describes a protein:
Function:
Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. Activates the transcription of the uhpT gene. Acts by binding specifically to the uhpT promoter region.
Subcellular Localization:
Cytoplasm.
Sequence:
MTYRVVFIDDHDIVRSGFAQLLSLEEDIQVVGEFSSAKQARAGLPGLQANICICDISMPDENGLDLLKGLPSGMGVIMLSMHDSPALVETALERGARGFLSKRCKPEDLISAVRTVGSGGVYLMPEIAQQLARVAVDPLTRREREIAVLLAEGMEVREIAESLGLSPKTVHVHRANLFAKLGISNNVELAKKVLNL
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MKTTSPQDIRLCEHILTQLYGHACGEIGSILLNRGRLPFSSLLRMSCLTGNSIRAALVVLIHQNCVLHSDTSLLTTAAGDPNPSSSGPEYFEAIPDEILTRVRFGQFVNLAYEQFGIESKLIVECLLDNGKLRVGQLVTMVCEQYYSQRKRLDETDDGLQHSPVKMPQIVKSNVLNLLAERYLKPSHPKHSINPTDLELAYEKQLIAKLPGVPSPKEIKAVKEQVMDMMATEETQAFEEMCSFGQKQRASNSAQNDRKAQTKRQKTEDVSLQDDMYIRVNYARFNMKIRNSIFEQECFRSYNLEAGLVMRAMLILAETKQQDLNDLVSDPISAQAIVMKLGQQSNIVKTCFPARAANGQFNLKLKNTGDLVAEMLSVMGKQDDLATSTSSAFAPGSLSKGLAQLNPLAVVSEKKNNVLGGGSGSGGMREFKVEYARYSLELRKALVSRIIREKYGIEAARVVRILMHKGRLDEKHLAKFAMMTLKDSRELCLKLSAGKVIELQEVPKTNDRQPSRTFYLFFIDFQKLILNLTMMIRKSQTNLIIRIDQELKQRKNLLCKVNRTDVIEDQDGLLTVWERADLKKLKTLVQVLEVAKLRLERDLFILNDLPWLQ
The following text describes a protein:
Function:
Likely to be involved in the establishment of the head.
Subcellular Localization:
Secreted.
Sequence:
MKLLIALFALVTAVNAQNGFGQVGQGGYGGQGGFGGFGGIGGQAGFGGQIGFTGQGGVGGQVGIGQGGVHPGQGGFAGQGSPNQYQPGYGSPVGSGHFHGTNPVESGHFHENPHEYPEHHGDHHREHHEHHGHHEHHGHHRH
The following text describes a protein:
Function:
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein.
Sequence:
MVSAKFARNVVGIVGNVISFGLFLSPVPTFYRIITKKAVEDFSPVPYIATVLNCLFWIFYGMPFVHPDSLLVVTINSVGLALELIYLAIFYAYAAEQKNGRKKVLIGLAGEVVFTVLIVVITMLALHTHKNRSMMVGIICDIFNIMMYVSPLTVMKQVITTKSVKYMPFYLSLANFLNGCVWTAYALIKFDIYILVSNGIGAVSGAAQLILYAVYYRTTPKDDDNDNDVPQKPSNVQLSNA
The following text describes a protein:
Function:
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSADPTQVLAFETDCHIFDGCGFPSPGLHSFLFEPLWGDHDSNLYFNKPMLLALLGSIVIVGFFWAAFRKPKVVPGKLQMVAEAGYDFIRRGVVYETIGKKEGEKYVPLVVSLFFFVWMMNLWSIIPVAQFPVTSIIAYPAVLAAIVYVTWITLTFKRQGFVGFFKNVTGYDKSLGPVLPLAMLIEFFSNILIRPFTHAVRLFANMFAGHTLLLLFTIASWYLLNGVGIAYAGVSFIMTVVMTAFELFIQALQAYVFVLLTCTYIQGAMAEHH
The following text describes a protein:
Function:
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
Sequence:
MKIGILGGTFDPIHYGHLWFAEYAREKFKLDKVFFIPNRVPSHREIPIATSKQRYEMVLLATLNNPYFEVLPIELEREGVSYMVDTIRDLSTYFSNAELYLLLGNDAFRDFLKWKDPYKIVEKVSIIVGSRGEEYYTNDLKDFIKTFENKIFFLDFPYYPISAKEIRDRVKKGLSIKYLVPENVEEYIIKNSVYCEEDQKDVK
The following text describes a protein:
Function:
Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).
Miscellaneous:
MISCELLANEOUS: [Isoform 12]: Derived from mouse ortholog data.
Subcellular Localization:
Cell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Nucleus matrix. Note=Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.
Sequence:
MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMDLTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADANGNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPPTPLGPLGCVPTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTPPSFSPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDTPEENPYFPTYKFPELPEIQQTSEEDNPYTPTYQFPASTPSPKSEDDDSDLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILPREDRKTNLDKDLSLCQTELEADLEKMETLNKAPSANVPQSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQFSSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVGVPGRRSLALTPPLPPLPEASIYNTDHLALSPRASPSLSLSLPHLSWSDRPTPRSVASPLALPSPHKTYSLAPTSQASLHMNGDGGVHTPSSGIHQDSFLQLPLGSSDSVISQLSDAFSSQSKRQPWREESGQYERKAERGAGERGPGGPKISKKSCLKPSDVVRCLSTEQRLSDLNTPEESRPGKPLGSAFPGSEAEQTERHRGGEQAGRKAARRGGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
The following text describes a protein:
Function:
Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). Participates in ovule development.
Subcellular Localization:
Nucleus.
Sequence:
MGIKKEDQKSSLSLLTQRWNNPRIVRVSRAFGGKDRHSKVCTVRGLRDRRIRLSVMTAIQVYDLQERLGLSQPSKVIDWLLEVAKNDVDLLPPLQFPPGFHQLNPNLTGLGESFPGVFDLGRTQREALDLEKRKWVNLDHVFDHIDHHNHFSNSIQSNKLYFPTITSSSSSYHYNLGHLQQSLLDQSGNVTVAFSNNYNNNNLNPPAAETMSSLFPTRYPSFLGGGQLQLFSSTSSQPDHIE
The following text describes a protein:
Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Sequence:
MESLNSYGVPKAEFIEDIKAAAPTPEAAEKLYREKTELMSKYRMLETHFLEKQQNFKRSRPSVAENLNAIKKLEAMADKGDVKTNFQLADSLYSTATINSESTVCLWLGANIMVEYPFSEAKTLLTENLAALDKQIDDISKNLIFLRDQIITTEVTLSRIVNHLIQLNKKK
The following text describes a protein:
Function:
Plays a role in the positive regulation of NhaA.
Subcellular Localization:
Cytoplasm.
Sequence:
MLHLNYNHLYYFWMIKKKGSVAKAAEALYLTPQTITGQIRALEDRLNGSLFKRVGRNLEATELGELVFRYADRMFSLSYEMLDLLNYQKDNAILFEVGIADALSKALSSRVLLSVVPNDGSMHLACYEATHESLMSRLREHKLDMILSDCAGESLKYPEILSKKLGECGVSFFSAETYSADFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLNVSILGEFDDAAMMKAFGYLKRGIFVTPSVYPQEVVSHGMHLLGETLDVKEEYHVMFAERMIQHPAVKRLLETDFSDLFAGLDTQVQQC
The following text describes a protein:
Function:
Plays a role viral replication by forming a complex with UL26, thereby contributing to increase its stability. Mechanistically, prevents the proteasomal degradation of UL26 by inhibiting its ISGylation.
Miscellaneous:
MISCELLANEOUS: Major target antigen for the anti-CMV antibody response.
Subcellular Localization:
Virion tegument. Host cytoplasm. Note=Expressed exclusively at the cytoplasmic level during the late phase of the virus replication cycle. Also found in dense bodies (By similarity).
Sequence:
MSSRRRSSSRRSGEPSTVIYIPSSNEDTPADEEAEDSVFTSTRARSATEDLDRMEAGLSPYSVSSDAPSSFELVRETGGTGAAKKPSEKKRSSSRRQPQIAAGAPRGSPATPKAGKSPKVSRPPSVPSLPENGAGGGGDDNSSSGGSSSRTTSNSSRSTSPVAPGEPSAAEGDEFSFCDSDIEDFERECYRVSVADNLGFEPSVVAPQHVEYLKFVLQDFDVQHLRRLNECIPMPAFALTSLVDPVLNNVAPGERDLTRRIITHAVIINYYYVAQKKARHMVEAIRTTVRGDTVRRVAAQVNNQSRSGRAAALALHFLTSRKGVTDGQYATSLRRLDEELRHRGTPESPRLTEVYQTLRDYNVLFYTAHYTSRGALYLYRQNLQRLNENHRGMLRLLSVEEICEEHTLNDLAFLVGVELMITHFQRTIRVLRCYLQHQLQSISELCYLIYVQLPSLREDYAQLSDVIYWAVSQNYDYALYASTPALFDFLRVVRQQDAFICTDYVYCALRLLACPDRPIIGDTGGSSSSQRLVGEFMVRDPLLRDPRATHLRQKLITRDICVARLQAQPSSRHIPVEHTGVSSVTLLKIFSQVPPDEREEDTLREMALKAFMEANGNHPEQICRSPPPPLPPRDYPQRDERDRHRRDRRDSGEYCC
The following text describes a protein:
Function:
Serine protease involved in intramembrane proteolysis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MNRSGRVGPLPPLQLSPRRQSRMLTLEETTNASPGASSVFWAESAPQSPLRDTITPSHVNLIKSPTTATRHSRLGLFNSSHTTIVTQLSYRDDQSEHASLDLADASSPHVSKRGGTYLQGLLQYVVPHQGRLDPEFSPFGHMYTLYVPDSADQLYFDAGAYNGRVLINGEPPQQPVTVAHATTAQVVVLEVFSQPPTTVRTAPDLVTPDADLGGPTTETEGTEPDALMQVRVSYSLHIVRVPANDSRLAPPIKSRAQFLEEAVQQPPNDEAMMVVRARTSEFPDDLTLVPGTLLDAEVVTEDWAFGTTRSVRPESGWFPLACVEPMTQHAPRLQASCRLGLAWENWPTQLPSMPARGQQRRESHPSQREHANPDMPDRDGMSDDDDYSDSGWLGSIYCGGGVPYMTVLLCVTNLALWLASLGSDEGTATLQENPLIGASMKTLRDYGACDPHSLREGQLQLLVSPVLVSRGVIALIHDIICLALMGVPFEHAHGAWAMVVLAVCATSCGTAVAAVATAPWITTGPAALVAGLMATNVGVVVADEVQGARRRLVLWTCSMVLVTSVILALFPGASWWYLLGGFFGGAAAGLYFHCRSEDTLSAKLAVVDPSRRAFQTRRARYALLFLLVTFVVTLESRRKKQAVLPCPCHRLTCIDLATRPPTLN
The following text describes a protein:
Function:
Responsible for physiological and behavioral changes in mated female flies. May contribute to the toxicity of seminal fluid and the decreased life-span of mated females. May also affect neuromuscular events after mating concerning sperm storage and egg release.
Subcellular Localization:
Secreted.
Sequence:
MTDMWSLKICACLGLLLLFKPIDSMGWQGPKVDCTANGTQTECPVACPETCEYSGNGPCVKMCGAPCVCKPGYVINERIPACVLRSDCPKDVVRKEDMLLGVSNFKCFSRNYNCS
The following text describes a protein:
Function:
Cardioregulatory neurohormone that increases heart beat rate during adult wing inflation; has no effect on beat amplitude. The effect of CCAP is both ino- and chronotropic (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MRTSMRISLRLLALLACAICSQASLERENNEGTNMANHKLSGVIQWKYEKRPFCNAFTGCGRKRTYPSYPPFSLFKRNEVEEKPYNNEYLSEGLSDLIDINAEPAVENVQKQIMSQAKIFEAIKEASKEIFRQKNKQKMLQNEKEMQQLEERESK
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSNKTLAFLKINQSSPICHKISSVSTILAMLALYLWDIVGKINETYPKLELTSGIMDAMGDALVVGISVINTLSANILNRKQQLSINASVKKIDIQTNRSKLLHVSVHCVVCLTFSWDIFSRNRSLGWAAYKYNLVPLFFLYKFQLFALQIHNLATKIERRFNILHREMAQTCDVDQITNCMKTHYVLSKLMENISTIYGWQILLMYKMLALYIVGGLYFIHLLKSSGLNFHVAEAICYLLWNKFLIVGCVVLVFSCDRANQEAEKTPQLCRNLKKTKIMKQFLKQVDHLAPTIRLPQGSPVDRRAFFDIISDIINYVVIVLQFDG
The following text describes a protein:
Function:
Transcriptional regulator required for the aerobic growth on D-malate as the sole carbon source. Induces the expression of dmlA in response to D-malate or L- or meso-tartrate. Negatively regulates its own expression.
Sequence:
MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLEQTLNVVLLHRTTRRVTITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISSFGFGRQVVAPALLALAKAYPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARKLATNYRILCASPEFIAQHGAPKHLTDLSALPCLVIKERDHPFGVWQLRNKEGPHAIKVTGPLSSNHGEIVHQWCLDGQGIALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVSRLATSAKVRITVEFLRQYFAEHYPNFSLEHA
The following text describes a protein:
Function:
Has a role in the nucleotide excision repair (NER) pathway. Acts in both transcription-coupled repair (TCR) which removes damage from the transcribed strand of active genes and in global genome repair (GGR) which removes damage in untranscribed DNA. Involved in the repair of short-patch mismatch during meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MPPKRKASKNSVRGRKRRTRTNNLPLNPEVKEETVVSSTHRQTRSQSKKPSLSSSAEPPSESLDDNISALNSLQRSASSSEKGSDEDNEKLGSSEDDEFDDDFDTWEQVDLSPNKQEDKKDLHIVTQHITPQLTKESKKGSSSAMDKSIRLSIHIMHFTCLLYHGSVRNRWLMNSLLLDGLRDLLVEKQPSVVEAWVCSSQTHEDLLKLLNGLRMWWNKSFKIESHGLRKLGYRTLKQGFDIGFSPEIFHNFHEYQASLLSLKGSRDLAAQGFTALCRSLNLKARLIFSLQPLTFSTASYDDWSPHILPEETSTSIDDDLRYPIFWTEIYDQSEKKWIAVDAVVLNGVYTNDMTWFEPKGAYAESKHLRMGIVAAYDNDLYAKDVTLRYTDYQSSRLKKIRHVSFADKYFDFYKAIFGQLAKRNKDAEDIYEEKELESKVPIREPKSFADFKNHPEFVLIRHLRREEALLPNAKPVKTATFGNGKKATSEEVYLRKDVVICKTPENYHKEGRVIKEGEQPRKMVKARAVTISRKREHEFRVAETNEPVLQGLYSSDQTELYVPPPIKDGIIPKNGYGNMDCFVESMIPKGAAHLPYRGIAKIAKKLNIDYADAVTGFEFRKHRAIPVTTGIIVPEESAQMVYEEFLECEKIRIEKQQMKERKIIYGQWKHLLNALRIRKRIEEQYA
The following text describes a protein:
Function:
Essential for the fidelity of chromosome transmission. Required for the DNA replication block checkpoint. Component of the RFC-like complex CTF18-RFC which is required for efficient establishment of chromosome cohesion during S-phase and may load or unload POL30/PCNA. During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC. The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit. Dissociation of RFC from the clamp leaves the clamp encircling DNA.
Subcellular Localization:
Nucleus.
Sequence:
MVDTAPYIGSLGRSSLFDTGDIEQAPGNNAIGINEEDIHAFVSSTGETVQLKKKPAKLATGNISLYTNPDTVWRSDDTYGININYLLDKIEASGDDRTNAQKTSPITGKIGSDTLWVEKWRPKKFLDLVGNEKTNRRMLGWLRQWTPAVFKEQLPKLPTEKEVSDMELDPLKRPPKKILLLHGPPGIGKTSVAHVIAKQSGFSVSEINASDERAGPMVKEKIYNLLFNHTFDTNPVCLVADEIDGSIESGFIRILVDIMQSDIKATNKLLYGQPDKKDKKRKKKRSKLLTRPIICICNNLYAPSLEKLKPFCEIIAVKRPSDTTLLERLNLICHKENMNIPIKAINDLIDLAQGDVRNCINNLQFLASNVDSRDSSASDKPACAKNTWASSNKDSPISWFKIVNQLFRKDPHRDIKEQFYELLNQVELNGNSDRILQGCFNIFPYVKYSDNGIRKPANISDWLFFHDLMYQSMYAHNGELLRYSALVPLVFFQTFGDIANKDDIRMKNSEYEQRELKRANSDIVSLIMRHISVQSPLMASFTDRKSLIFEILPYLDSMISSDFNKIRNLKLKQAIMEELVQLLKSFQLNLIQNRSEGFDVRGGLTIDPPIDEVVLLNPKHINEVQHKRANNLSSLLAKIEENRAKKRHIDQVTEDRLQSQEMHSKKVKTGLNSSSSTIDFFKNQYGLLKQTQELEETQKTIGSDETNQADDCNQTVKIWVKYNEGFSNAVRKNVTWNNLWE
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MYSEWKSSSKIVTRTRVCTGRGEVLVTTRSGGVGTCTVHFRGILEVIGPTVESAIWVDESHMFSDAFGHKHPTSPAQLHPEDPLGISDESVRRFPEEELRQLFPEGSGNLLSENFNPTWYLLENYNSTSFSDLKAGLMSLKRKVGQLQEGPSSFLKSNVNAIVICLDVLHELQKAMEKDKQEMGSDLTEKLSEAVLRSKEEAENIFESILARKDQADSTRNALSILQKFRFLFNLPVTIEKNIQKGDYDVVINDYNRAKSVFQDTEVAVFRRVFQDVEQRVQRFRNALMDSLKQLPMPVEEQKRLIRYLISLEVPGSPAWDAVRHNYNWLLNSVETCKQKHLSVCKSLHVYLSVAKGDEDERKRSEESHPDLPRQVLFVEEVTALFQKHLCDFWKLGLSYFAGDFLVEDASVNDRERDEKELREMVASLVGQLSWEVRVALLPPTHHSLAKQAHRVSAWPGHKTNEKLGPWLPQCLRSIRQCYLSLLKLDIPEENTSLVQRLIFDLRVHSMTCLFGQAAEDVRNLLKSEVWRLEKDDRCGGTTQLPLMFENRVVETLQLVRENILQSGPREMEVFEQINVQGTIKQYAQAVLQAFVETLEKCALSPDRLSPIIDAIGSNVEILPPGQRAKSFKQKREDSLTTPPLEKRLLIVLSNCSFTSRVVIPRLQESFERHGYPDMSLVIQTTLSRLAELDRKLFQKLLEAKCDPIVGAIEPNMYAGAFDWKKCAEPMGVSSYIKEALMSMIEVHAEVYTISPPLVSRIMTPLAQNVAEEISRLYECTEKFTKHGNMQATLDLRALEEAVDSYRTQNTGKFFMICRSRLDPFSSTKDKELVDELLKRFRNQMRLQLLCFKEDVVVSV
The following text describes a protein:
Function:
Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MPDGGHRHRAQPVSVRPNRHRRTRVSRAQRRHAQQIRRRRRVAGGFALSLLVVVVVVAVVVGAKLWQTMLGFGNDYTGPGKRDIVIQIRAGDSTTAVGETLLKHGVVATVRAFVDAAHGNTAISSIQPGFYRMRTEISAASAVARLTDPHNRVGKLVIPEGRQLDDTTDMKTNVVNPGIFALISRATCVDLDGTQRCVSVADLRAAASRSTPTMLSVPRWAVGPVMELGTDHRRIEGLIAPGTFNIDPSASAETILATLISAGAVEYMKSGLVDTAKSLGLSPYDILVVASLVQQEANTQDFPKVARVIYNRLHEHRTLEFDSTVNYPLDRREVATSDTDRAQRTPWNTYMAQGLPATAICSPGVDALRAAEHPVPGDWLYFVTIDSQGTTLFTRDYQQHLANIELAKHNGVLDSAR
The following text describes a protein:
Function:
Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
Sequence:
MADVYLDNNATTRVDDEIVQAMLPFFTEQFGNPSSLHSFGNQVGMALKKARQSVQKLLGAEHDSEILFTSCGTESDSTAILSALKAQPERKTVITTVVEHPAVLSLCDYLASEGYTVHKLPVDKKGRLDLEHYASLLTDDVAVVSVMWANNETGTLFPIEEMARLADDAGIMFHTDAVQAVGKVPIDLKNSSIHMLSLCGHKLHAPKGVGVLYLRRGTRFRPLLRGGHQERGRRAGTENAASIIGLGVAAERALQFMEHENTEVNALRDKLEAGILAVVPHAFVTGDPDNRLPNTANIAFEYIEGEAILLLLNKVGIAASSGSACTSGSLEPSHVMRAMDIPYTAAHGTVRFSLSRYTTEEEIDRVIREVPPIVAQLRNVSPYWSGNGPVEDPGKAFAPVYG