lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Sequence:
MAQLGFDEIQQLVTEVQRLTTQLPQSIQSIHPQTSHDLYNFLYYAPFIFDLKLPLTLDMRKMIIAVLWYNLSMGRRSVFDQLVGNSLKIIIPMDDETTAFSSDAQRQQSVLVDDSDYLPLEYREGQQGKACGHVFDRGEGIYRCRQVTCALDDTCVFCFRCFDAAAHEGHDTTMSIALGSGGCCDCGDPEAWKLAVYCKYHSPQSSDAHVASMDTQSILDGKPDIEKIPLAVTDAIRQTITTVLEFAISSLARSCENPQFVNDPAIIKAKHAPDVVMGEDKLMNFSCVLWNDESHSFQEVIDQVAEATNCTEAYARSVAVAVDKRGRYPVRTSDSIPLLIGVASIISRISLTVSIRPTRDVFREEIAGVLVNWLKTLSRFIQGSQVIDGVHYESIAELVRSIICEELCNPLLTDLGTYNSTSPFIDELQSPTPVMLRPHRPRVHYFLVLDSYFWKEMRNSLRELYIGTLIVNGDIFKKSMAVHFVNSYLEVSRCYLFHDREIDLSIMNFTVQIFTVPTIANYLMHHTLILPYMLSLLKAHFLSDVLPDEYSLKTKYYETIQKATVEFKPIYPVLRFDGEAVRNKRHAHLLFDVRYLLSSRNVCNSASANNTLATATTNGRVSILLRFLDLCMVWQGMNPQMRSLHNHIEYETDDWLHAFNHSINILPLMRGFANCFFSSVSENSAANLLNAMSETRDALLKWTLHRHVESTKNWQTMQISIAGAMRRRETVRDGFHIVTLVPGRPCRIPDYHVAFQPISFHKCLHWLLANLLRNTAALLRHTDSVDKRASIVKHIFDIVADSPTIAIEPASIDSTHILDMDEMLRCLSVEDRMSLIFDFPLRSIVLVSQIKAGVWVRNGYNVREQAKHYADAVLREAHDHDMLLLQYATVCLGPDKLLTMLVDRYGLVSWFQGRTISSDTAHYESAQISSFVQDMLQVIMILLTERSNVAAISAADELRREIIHYLAVHRSGTAYSELSRRIADSLVDAAADCMPDVDDMNEPTVNSTSVDAILQSVANFKFPDGTADHGLYELKDEMYANVDPWFWHYTRNEREDLGEVLRKRLEKKRALNRHHSNDAALEEEAVRRPKLCQLVQGTGFDRLNNLVHSPIFNQIIFYSLWNVTRTVAESGQEPVNSEMILAEAVHLLMVGFEIVGASKTNVAHTNVSDIGFIQHAVLERVSIPVRKGAEMRPTTLLELILSLVDRANEEDIKEQAPRLRFLVRRFEEMGGLTAETTIVGWRDKSNWDLGKPRLSSDIQSTNSSNNDTESSEQEKRKLAVKARQANIMAQFAQAQKSFIANFGDDLDDLDDDEVDDPITGDGSHAEDSAASHSDHRTWKFAAGTCIVCQEDASSGDKMYGMLCLLRHTTVCRQISFGDVSSLAKIITALPESFDTVPEKNEMSSVDDIPASGSQTPVTLGHSVDAMGSDPNLKKFANLNSSGVSSSSPIASTNSVPLKQISVEGITATSCGHLMHYSCFDTYTHSIDTRHLSQPTRNHPEDTDAREFMCPLCKSLGNTVLPVVWSNRHESVNWRGSNVSWKHTEKYDDRQLLGEMRLWLTSSELVHVSGASKMDTSTGAQSDREACADLSSDGMVDILSNDMDADSNSSTGWTADESNDQNTAVHHSSISELFNKLFVDHLSLSTSTLTFKGGSDSTQSHELLGKMQSVYSRNMYAELKDLVEEMRDDGKPNPFETNLEPAMLICTRMWDLFAYTISSLEILGRGSSSSWTPGLLSSHANQLVHIGVLDTISSQMHMCLRLLSEATLGTAVYAKCPQATLMMYGNRFLASLFGDHSVGDVKENHVSERDSQAHPPALLRDGFSHLVALSMSIIPARVTQRTKNETEVFQWMRVMWVFELVRCVVSVVESILLHGDTWITDPQVVFALNEHTQDASTYFDTTPMTKDKNQSDYIVTEPANLQSELADTPVEDDSKYAGLAHLINVVLNGMKLMPDAKVYVEKTIRPDMVCALFKRVGLVYARRCAVLLYARFGLVPPGGAVGFGFDLAQSENSEDLGPDVTDRVNAANDENELMRLCLYLDLPKVDTLVSLPIVHDRVFGQMVLHWVHDFGRTMANHFGVVWSTEAARRREKERQKTVGATRSAMISISSDAMAPPLPPQVSLELPLVFELAKLPQRLAKLFEESRRKVCRRCGTVPLDPALCVLCGMILCSQSYCCSDEDHGECNQHIRECGGSVGIFLLIKQAMMILLLPNGKGTFMDLPYLDAHGEVDPQLRRGRPLFLNRKRYGEIRKLWLTHAIPSYVARKIDQAFDAGGWTTF
The following text describes a protein:
Function:
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MRALITFALLCLLYITVQGKVSTPKVHVYSHFPGEYGKPNTLICYVSSFHPPDISIELLKNGQVMSDTKQTDLAFEKGWQFHLTKSVAFTPEKGDEYTCSVRHMKETKKFSWEPNM
The following text describes a protein:
Function:
Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
Subcellular Localization:
Cytoplasm.
Domain:
Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
Sequence:
MVDLKRLRQEPEVFHRAIREKGVALDLEALLALDREVQELKKRLQEVQTERNQVAKRVPKAPPEEKEALIARGKALGEEAKRLEEALREKEARLEALLLQVPLPPWPGAPVGGEEANREIKRVGGPPEFSFPPLDHVALMEKNGWWEPRISQVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSFGKDVRGLMRVHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLNNTALATPRILAMLLENHQLQDGRVRVPQALIPYMGKEVLEPCG
The following text describes a protein:
Function:
Magnesium-dependent phosphatidate phosphatase which catalyzes the dephosphorylation of phosphatidate to yield diacylglycerol. Acts redundantly with PAH2 to repress phospholipid biosynthesis at the endoplasmic reticulum (ER). May function indirectly as repressor of multiple enzymes involved in phospholipid biosynthesis. Is involved in the pathway of galactolipid synthesis in the ER, which is required for the membrane lipid remodeling, an essential adaptation mechanism to cope with phosphate starvation.
Subcellular Localization:
Cytoplasm, cytosol.
Domain:
Contains 1 Asp-Xaa-Asp-Xaa-Thr (DXDXT) motif, a catalytic motif essential for phosphatidate phosphatase activity.
Sequence:
MSLVGRVGSLISQGVYSVATPFHPFGGAIDVIVVQQQDGSFRSTPWYVRFGKFQGVLKGAEKFVRISVNGTEADFHMYLDNSGEAYFIREVDPAANDTNNLISGSENNNGNQNNGVTYRLEHSLSDSGTGELREGFDPLSRLERTESDCNRRFYDFQDDPPSPTSEYGSARFDNLNVESYGDSQGSDSEVVLVSIDGHILTAPVSVAEQEAENLRLNTPQFHLAPGDGTEFCEGNTEFASSETPWDTEYIDKVEESSDTANIASDKVDAINDERNDLDSHSRDNAEKDSHDAERDLLGSCLEQSELTKTSENVKSEEPGPTFEDRNLKEGEFPLRTIMENDRSEDEVTIESIDTLVDSFESSTTQITIEEVKTTEGSRISVDSNADSECKDEQTSAETAILFNNQESSISVDSNADSECKDEQPRISAETAILINNQEGGIIESEDQDSERVSIDSTREEVDKDNEDRKTVVSVGVTSSVDEGEPDTDQRYELSLCKDELRQGMGLSAAAEVFDAHMISKEEYINSATSILESENLVVRIRETYMPWTKAARIVLGKAVFDLDLDIQPDDVISVEENESPKPKDDETTITPSSSGTRWRLWPIPFRRVKTVEHTGSNSSSEEDLFVDSEPGLQNSPETQSTTESRHESPRRQLVRTNVPTNEQIASLNLKDGQNMITFSFSTRVLGTQQVDAHIYRWRWDTKIVISDVDGTITKSDVLGQFMPFIGKDWTQSGVAKLFSAIKENGYQLLFLSARAIVQAYLTRNFLNNLKQDGKALPTGPVVISPDGLFPALYREVIRRAPHEFKIACLEDIRKLFPTDYNPFYAGFGNRDTDELSYRKLGIPKGKIFIINPKGEVATGHRIDVKKSYTSLHTLVNDMFPPTSLVEQEDYNPWNFWKLPIEEVE
The following text describes a protein:
Function:
Protein kinase that may act as a negative regulator of filamentous growth and flocculation. Appears to have a role in normal cell wall and septum formation and in cell separation. May have antagonistic function in the regulation of beta-glucan distribution between the sites for cell wall and septum assembly.
Sequence:
MHSLKRRRNHAPDWQDFYKNGVPQEVIVIEDSASPRLTPNLPPPFSVHQLQSFVPPQPPSSSSPSTTGTVAVPINGANAVYPSTNSVSLPQSYDPWLDANGVVPLPHDVASHPSYMVQSPTSYHACSNNQSPFPHSHHPPLHNPLPVSCQPVLRPPPVPQVPSHWYPVSLPSPNLPHQPISKPPVIPNLPKLQVHPNRLPHPIHNHPYSSPTSYPPPLCPATYCPSNPPQLAPATAIAPSSQSSQHKSVNYSVTPSSINNHTAVPLSPTLAVWLPMTQPTFQPPSANVYQPASNANQVITPVSISDYRPPKKRKRAAWPPYKKVDRVNVPVVHDTTAFDPSTFDDDDGHYKVVPNSKFANRYTVVRLLGHGTFGKVIQCYDQSTGRHCAIKVTRAIPKYREASLIELRVLQTIAHSDPTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQMLSQQLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSATFEDEYHSSVVSTRHYRAPEIILGLGWSYPCDVWSIGCILVELFTGQALFQTHEDSEHLCMMEKILGPFDRNMISRSSRTSQRFFKSDGKVRYPLSNTPKKSINYLQSLQTLEQIFAVSSPEVALLLDLLKKVFVYDPKRRITAKEALWHPFFTQPISSNL
The following text describes a protein:
Function:
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with regulatory proteins of cell cycle progression including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
Subcellular Localization:
Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Nucleus, nuclear pore complex.
Sequence:
MAKRIAEKELTDRNWDQEDDGEEAGTFSIASDDVMKNRAIKKAKRRNVAEGESGGAFKAFKGFSLAPATATASFSGFGNGAGFKPMASLTNGSVASVAPSFTGFNVPASAKTNSGPLTFSSSTPSKPTDSEVTSNGSAPSSKEYNRQLTALNCSVRDWITKHVNDNPLCDLNPIFRDYERHLASIERKYGSGAADETPGKPLASCAAAPPTVSLKNKDDKPPAEKPAAPPGVSFNFGKKVDSSVLGALSSGGAPSFSFSSSSSSSAVFGSAVSSVSPVVNSDSNSQTADENGEDSEEPPVPVVKEIKEKDAFYSKKCKLFYKKDGEFKEKGVGTLHLKMTTESKLQLLVRADTNLGNILLNIMVPSSMPCSRTGKNNVMVVCVPNPPVDDKNPSVPVPVLIRVKTAEDADQLHRVLQEKKA
The following text describes a protein:
Function:
Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme.
Sequence:
MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLSDFTRRAYDPCKLSYPKGLLLRQTLLRG
The following text describes a protein:
Function:
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
Sequence:
MSLIRSRRGSFVRTLKDLDPDLEDLFYDGGLRASKRNQWFFEVAWEVANKVGGIHTVIRTKAAVTVDELGDQYYMIGPYVEQFVRMEVEVCEPTHNDAMMKALQHMRQHGMKVVFGRWLIEGTPNVILFDIGSGACKLNEWKNELWESSHLGIPWEDKESNDAVVFGYLTVWFLSKFKENMSPEPCIVAHFHEWISGVGLFTCHTRRLGISTIFTTHATLLGRYLSAGSCDLYNNLHTFSLDKEAGNRGIYHRYCIERAAAHCADVFTTVSEITGLEAEHLLKRKADLILPNGLNVQKFAALHEFQNKHALAKEKINDFIRGHFYGHYDFDLDKTLYFFIAGRYEFSNKGADVFIEALARLNYMLKRCNLPPICTHNVLNDDVDPVLCAFRRCQLFNSHQDRVKVIFHPEFLNSTNPLFGLDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMQQHIQDPQSYGIYIIDRHFKSVEDSVQQLAQCMFDFSHLSRRQRIIQRNRTERLSDLLDWKNLGIYYHKARNMALQRTHPELYGNSSEYPDGINKMPKPQSEPTSPSASRSSSPPPSLDDDEPDSEEEKQELSKIETETTSGRATPVNH
The following text describes a protein:
Function:
Serves as the scaffold for the assembly of a complex that links key players in the nucleation and termination of actin filament assembly with a ubiquitous barbed end-directed motor. This complex is composed of at least capping proteins (acpA and acpB), the Arp2/3 complex, type I myosins (myoB and myoC) and carmil. It has at least a modest ability to activate Arp2/3-dependent actin nucleation. CARMIL localizes along with the Arp2/3 complex, myoB, and myoC in the leading edge of cells and it plays a significant role in the structure and function of these actin-rich cellular extensions.
Subcellular Localization:
Cell projection, pseudopodium. Note=Found in dynamic actin-rich cellular extensions, including the leading edge of cells undergoing chemotactic migration, and dorsal, cup-like, macropinocytic extensions.
Sequence:
MSEEISPNDRKFITNLLTQKNQESLLLSIGDKISKKKNKKPSKRIILITKNRIFFLKPSQNKVKKDIHLLDIQEIKSSTSNEFTIVAKVDNKQFSYGLITNKTDEIINQIRVTFNHQFFGCPEESTFKCTDIKDSRLVEIEQKDLPCGGFVETYQSICDHLGVPPRDDICWDMTNIISSKNIRSFNIGEIELPTSAGDTIRCLLGALKYNNYFKSFNFNNYTFNKEQFGYLAEVLKCNSTVEDLSLNNVGLKHDTMPIIATALSSNKNLALTAIDISNNQIEDKGMTAFSSYVASSLRGIASLDVSNTNCNKAGISVLTNALKKNIKMSSTLSYLNLSGNKMEADGSAGLSSFLASPNTLKTLNISNTTPSMETIVGALVIGCAELKTIDISDNKLTKKEVPHLVRFIGASSTLKHFNLSGTKVPVENLKELVVAITSNIYLQDVVLDLKNNDLGIAGARMLASLATDKLSNVIYLDVSENDFGDEGVSVICDGFVGNSTIKKLILNGNFKQSKTKSRPSAIESVISLLESECPLETLHMTVGNSKSPLKADILSLIYSLATNSSLLELDISGHQMGPKGAIGLGKALQTNKTLHTLIWDDNLTTAIGFAGFQVGLERNLTLKNMPTPLNDIIQCHREPKFQQIWKEIDSCINRNQSPTRAFEGNGGNSIGATNLSFLASGQQQGVEKLLNKIKSIGRKVTDPNNILIVKDAESTEKVIGGIHLIKESIHASLEMELNQKLKDFVQVVNDVINAKKNEMTQQILESMQNTFQSMDGPTIKRLATTIQYGSKDVDEQQIHSTLVKGAGAELSSRAHECFISALDIASDYTYEKITIGLDSVFKDLILEESQAQNEASGATPIPDSPVPTRSPQPTSPPITPQPTPTTNVPPVTAPRTGAAAPLKPANPPPVSTTTTPPVSTTPKPTQPVSKFGAKLSANSAVAEAIARNMGGGAPPIRKPVAPEPEPEPVTPTKDVTPLKSKPVVAPRSTPTTSTPTKTPVKKPSGPSVPGSLSDAPESDSAELTHVTASRPHIASKRKPPTRRPRPPTEN
The following text describes a protein:
Function:
Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MDFTDPTTLGVLVAAVVGLITILLIVLKSLRSSNKNRVLFVGLMDSGKTTIFTQLSQKEAEYPTTTRTFTSMVENKITLRIKDKEREIIDYPGNDRLRQKLIDLIHSRSLLRIVFVVDSAAFSKNARDVAELFYLVALENTDKVPILIACHKQDLSLAKTEKVIRNSLEKEIGFINKSRAAALIGTDGSDEKRATLTDTGVDFSWEDLKKQEVSFVTTSSYSADFGVHEIASFVRA
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
ILFSNLSNIKAHLVSYPALTSLYGTSLKYFSVGILFTFNPIILLIFVYSIRESFYSVFSSLTSGMLSIIISEALLFFTYFWGILHFSLSPYPLSNEGIIITSSRMLILTITFILASASCMTACLQVFIEKGMSFEISSIICIIYLLGECFASLQTTEYLHLSYHINDTVYTTLFYCVTGLHFSHVVIGLLLLIIYFIRIIEIYDTSTEWFINSFGISYIVIPHTDQITILYWHFVEIVWLFIEFLFYSE
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MLPRQLSRAPRALGYVLPRFSPPSSVLRTVTPAFARSTQLSLRRILEKRGYAVSAVAEKDDDFFSGAELAPSSNTVVIPPQLDDPGHPASEPLVDTVPFESLKGRINHDTLKALTVKPFKFTAMSEVQKRVLGLLPHLSGGKLRSKAREEAEQEGEVEMKEEREDLLVKAKTGTGKTMAFLVPAIDARINTLERLSKAPNPDGTIPDKHAQGRNHRAISRSHLGALIISPTRELATQIAVEAEKLCTWHKDLTVHSFVGGESRLRQLKEFSRRSKDVVVATPGRLRDLISEPLVKDALAKTDMLVLDEADTLLDMGFSEDLKFIIDHLPKERQTLFFSATVSKEIAAIARHSLRKGHKVIDCVPKNESNVHLHIPQYATVVPSSADAMPHIMRLIAQDQMANPKSKIVLFLNTTKQTMLTATLVRELVDTLPAQTAVYEIHSKLDQNKRTRSSDKFRREHRPAVLVTSDVSARGVDYPGVTRVIQLGVPSTTEQYIHRVGRTGRAGKEGRGDLVLFPFEAGFLDHLKGIPIQRISTSDLTSDVIAKAPSSYASVIDSLPSAVESLLPTLDPKAVEEVFMSMLGYYHSKQQMLDASAQDILKGLKAWSVEGGGLIEPPYVSEEFLKKVGFSEKRRNTRNGGGGSRGGFGRSSGGFGRGSGGFGKRDGGRREDSGGFGGRGQGGGGSGFGARRDGGGGFAGKSRSGGFKRDY
The following text describes a protein:
Function:
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
Subcellular Localization:
Cytoplasm.
Sequence:
MFDLEYQLKNLPDKPGVYLMKNNLGEIIYVGKAKILKNRVRQYFQKSQKHSEKVKAMVKNIEEFEYIITDSEIEALILECNLIKKYRPKYNILLKDDKHYPFIKVTLAEDFPRVISTRKVTKDGSKYFGPYVDGSSVKDIIELIKKTFPIRTCKKNIVEEAKAIRPCLNYQIGLCKAPCAQYIKKSEYRETIDDVIKLLSGKHLDIVENFKLNMEKAAENLEFEKAAMLRDKINIIEKIGEKQKIILNNFDNEDYISLYSDGKDTCFQVFFLRNGKIVGREHFIIEDTFDTNSSTLISNFLKEFYGGTAYIPKTIYVPNIEDEALLEQWLTLKKESKSTIKIPIKGEKKNILVLVEKNAKTTLENFKLKYLQEKALYDNVLKDLKNILRLQEEPIRIEAFDISNIQGFDSVGSMVVFEKGRAKPSDYRRFKINTVKGADDYKSMKEILTRRFQHGLSEIKSIQDRKLEFSSGKFSVFPDLILMDGGKGQINIALEVLNAFNIDIPVCGMVKDNKHRTRGLIYNGEEIIINKYGSVMKFITRVQDEVHRFAISYHRSLRGKNSFHSLLDDIPNIGEKRKKDLLFNFKSIDNIKKATYEELLSIPSMDKKSAECVLEFFK
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MNDFDECSPSAASMYLPGCAYYVAPSDFASKPSFLSQPSSCQMTFPYSSNLAPHVQPVREVAFRDYGLERAKWPYRGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDPKTGAGGSGGSPCAKATTGSEPKGAAEGSGGDGEGPPVEAGAEKSGGAVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF
The following text describes a protein:
Function:
Is involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MASEADLKLLGTAVSPFAVRIRMALHMKGLPYEYLEQDLVNKSDLLVTSNPVYKKVPVLIHGGKPILESLAIVQYIDEVWSGKALNILPADPYQRATARFWAAYADDKLFAAYLGIFGAVTEVDRAEQVGETLAAVEQLEGAFIQSSNGKAFFAGDSVGFLDLVVGCHLFWLEAMGKMAGVAFLDTGKTPLLAAWAERFGETEVAKEAVPDADVVVEYAKKRQAAAAN
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC).
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane.
Sequence:
MAVYTQYVQGSASTSASVPPTLTRNTESSFNAFARVLQACKDLDPAARIDPDNGTALLFADACLRLGEEALDDAGYNARLQDQNLEDDDRAAWELEQSTWRLIHMLTSERLHRIGRKSQAPTEEQDKHAIQAYETPLAAIQSIFEKDEHLNELRIIREWLQETLIPRHIVEVRKGYLAFTKNRVRAEKRASVGGGPTSGDGRKLAFGSAASSSFAPRNRGKAVKNLDPDAVSRGEGGLELEDATYEKALLRTLFEYARAGRLDAAFDLCHQIDQSWRAATLRGAMLYHDPAVNAEPQDVDRVVGNRNRTLWKSACRKLSANPNLDEYERALYGSLAGELQSVIHVSQSWEELLWAHVNAKLEAAVDLKLDERHSWWSQESNPDLFDEGEHGAVQVLQGAIASIPTPAPQAGNASKSEIKVGSLHGVFDKLSQTQAHSIHLQANNPYRLVQRSIISNNLPDLFNRFADNLGDMQTALEPATFARLLRFFAHLILYLRLLSISLPDFACNAILSCYVQVLEAVGEVNLVAMYASSLEPQSATRSYANFLRSMDVNSSREAKANALRQAEQHDLDLTAVARCTVEMTFDELFPSIASEFDESSGLGGALKALGGSKKLDTIRFDVRLDGNEEALVKAIDWLTFDPTTYAEAITQSNALTRLFLSTGRLHAAKVLRERMPNEVLSSMDSLDLSMGQSIERAGWDTFFTALEAHVAYKHFWTTRPADAAASGARTADGMSKLERLNWVKALSQVVEQARDLDLVLLERDWLKIPLDTSGGGLETERRSRELFDIRQAYIPEIVFRLHDMLVESSSVVPINLNMALRLAEIVADERHKVYLEFIRSNANLLQDYMLRVREASLLLLNNGGDVFQKAVES
The following text describes a protein:
Function:
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (Probable). A molten-globule protein, it binds dsDNA in the RNAP, in vitro binds dsDNA but not ssDNA (Probable). Its position in RNAP implies it functions in both transcription initiation and elongation (Probable).
Subcellular Localization:
Cytoplasm.
Domain:
Forms a helix-turn-helix motif with helix 1 (residues 38-56) nearly parallel to helix 2 (residues 61-82); helix 1 contacts both Rpo5 and Rpo1N. The C-terminal region (residues 81-104) is required for DNA-binding.
Sequence:
MVSGMSTEEEKEGTNDEEVSEEREVEETSEEEFPKLSIQDIELLMKNTEIWDNLLNGKISVDEAKRLFEDNYKDYEKRDSRRKAKKAASKKVKKTKKKEKSVEG
The following text describes a protein:
Function:
Inner capsid protein that plays a role in viral DNA ejection into the host cell. Assembles into an extracellular trans-envelope channel completed by the internal virion proteins gp7 and probably gp16. This channel allows the delivery of the viral genome into the cell cytoplasm. Displays membrane-association properties, may therefore form a simple channel spanning the outer membrane (Probable).
Subcellular Localization:
Virion.
Sequence:
MLYAFTLGRKLRGEEPSYPEKGGKGGADKSAKYAAEAQKYAADLQNQQFNTIMNNLKPFTPLADKYIGSLEGLSSLEGQGQALNNYYNSQQYQDLAGQARYQNLAAAEATGGLGSTATSNQLSAIAPTLGQQWLSGQMNNYQNLANIGLGALQGQANAGQTYANNMSQISQQSAALAAANANRPSAMQSAIGGGASGAIAGAGLAKLIGSSTPWGAAIGGGIGLLGSLF
The following text describes a protein:
Function:
Hydrolyzes various disaccharides such as sucrose, maltose, and isomaltose with different efficiencies. Also hydrolyzes longer maltodextrins from maltotriose up to maltohexaose, but not maltoheptaose, palatinose, isomaltotriose, or isomaltotetraose.
Subcellular Localization:
Cytoplasm.
Sequence:
MSEWWKEAVVYQIYPRSFYDANGDGFGDLQGVIQKLDYIKNLGADVIWLSPVFDSPQDDNGYDISDYKNMYEKFGTNEDMFQLIDEVHKRGMKIVMDLVVNHTSDEHAWFAESRKSKDNPYRDYYLWKDPKPDGSEPNNWGSIFSGSAWTYDEGTGQYYLHYFSKKQPDLNWENEAVRREVYDVMRFWMDRGVDGWRMDVIGSISKYTDFPDYETDHSRSYIVGRYHSNGPRLHEFIQEMNREVLSHYDCMTVGEANGSDIEEAKKYTDASRQELNMIFTFEHMDIDKEQNSPNGKWQIKPFDLIALKKTMTRWQTGLMNVGWNTLYFENHDQPRVISRWGNDRKLRKECAKAFATVLHGMKGTPFIYQGEEIGMVNSDMPLEMYDDLEIKNAYRELVVENKTMSEKEFVKAVMIKGRDHARTPMQWDAGKHAGFTAGDPWIPVNSRYQDINVKESLEDQDSIFFYYQKLIQLRKQYKIMIYGDYQLLQENDPQVFSYLREYRGEKLLVVVNLSEEKALFEAPPELIHERWKVLISNYPQERADLKSISLKPYEAVMGISI
The following text describes a protein:
Function:
Probable transporter of a GTP-driven Fe(2+) uptake system.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MGHSDSSKTFRILMAGNPNCGKSTLFNQLTGLRQKTGNYHGVTVEKAEGIFHHLDHSVKILDLPGAFSLGGSSEDKQITSRVLIGHEAGDRILFVMDASLAERSLQFLLQILELNVPVLVAVTMKDVLEKKRVQLRLDLLSNEFGILFQYVNPKNGEGIKELKDRIVSPKAFCLPIRSFPWDSERENFLNDLLNSLSTEHSNSLKFVLTNSLKELSGEILQKGLPGLSLFSETPSKLIREKFERFGKRFTYLEELTQKSIYIKKILSNAIVGDPIPNERVLSKADKILLHPFWGLVSFLGIMALVFQALFTWSEMPMDWIESCVRNVGTFVGDFLEEGPLRSLIQEGIIGGVGAVLVFIPQISLLFLFIGILEETGYIARASFVMDRFMGKFGLSGKSFIPLLSSAACAVPAIMGTRTIENKSDRLTTILVSPLITCSARYPVYVLVIGAIFPSKNILGIFNVQALTMFGLFLLGMIASMFAALVFKKTFFKSDSSYFLIELPAYNTPSIKSLALTVFKKLKAFLSTAGQIILFISILLWFLANYPRIDSSLYPNLTDAELKKIQIRESYAGHSGKFMEPVLKPIGFDWKMGIGIITSFAAREIMVSTLSIIYGVGGEESTDDLKEALLKDTDENGKPVWGLSNSVSLLLFFAFACQCMSTLAVVKKETNSIFWPLFLFTYMTILAYSTSFIVFQVWQLFS
The following text describes a protein:
Function:
Transcription factor involved in endoplasmic reticulum (ER) stress response. Acts as a ER stress sensor and activates the transcription factor BZIP50 and the chaperone BIP1.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus.
Sequence:
MAIAEASPFADLPFPDDLPEFPHGPVGDDDAFALDGFDLDDLDIDFDFDLDLDLLPTDDVQLPSPPPPLATSSSSAGSPGGAGDSSSGSGAGADGGLKNDESSETSSRSASAGSDGKAMNGEGEDDKRRARLVRNRESAHLSRQRKKQYVEELEGKVKAMQATIADLSTRISCVTAENAALKQQLAGAGGAGVPPPLPMYPGLYPLPLPWMHPAYAMGAHGSQVPLMPIPRLKTKQPASAAAEPPAKKSRKTKKVASVSLLGLLFLMMLCGCLVPAVNRMYGAVDSREGIVLGPSQSRHGRVLAVDGPRDGVLEGVDSKLPHNSSETLPALLYIPRNGKHVKINGNLVIRSVVASEKASSRMCHSDGKTSCNQGQEDTSLAIPGHVAQLNSGEVMESAKAIKNKLMALPPGDGSIYRDDDELLPQWFSEAMSGPMLSSGMCTEVFQFDISPTTIVPVYSSGMHNASHNSTENLTSSQSDKVKNRRILHSMAVPLKGSTSNHTDHLKAHPKNESFAGNKPASSVVVSVLADPRVDADGRISSKSLSRIFVVVLVDSVKYVTYSCVLPFKTHSPHL
The following text describes a protein:
Function:
Catalyzes the conversion of dihydroorotate to orotate.
Subcellular Localization:
Cytoplasm.
Sequence:
MTPSLLKRVERAGAGAVTTKTILPRPSRGYENPVVVELPFGMLNAMGLPNPGIDEFEREFREARGSIEIPVIGSAGGNTPEEVAYVAGRLQDCGVDAVELNASCPHVRGHGLEVGSTPELMRELVSEVRRNVKIPIIVKLSPMVPDIASLGRSAFESGADALNAINTVRAMYIDVEAMTPVLSNKFGGLSGPAIRPIAVRCVYELAGICDVIGTGGVETWRDAVEMMLAGAKAVGIGTAIYRRGLEVFEEINRGLESYLLKKGLSLREIIGRARG
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MRLSSSGLPQQTQEGEQKCLNSELWHACAGPLVCLPAIGSRVVYFPQGHSEQVAASTNKEVDGHIPNYPNLPPQLICQLHNVTMHADAETDEVYAQMTLQPLSLEEQKEPYLPAELGTPSKQPTNYFCKTLTASDTSTHGGFSVPRRAAEKVFPPLDYSQQPPAQELIARDLHDNEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVAGDSVLFIWNESNQLLIGIRRANRPQTVMPSSVLSSDSMHIGLLAAAAHAAATNSRFTIFYNPRASPSEFVIPLAKYVKAVYHTRVSVGMRFRMLFETEESSVRRYMGTITGISDLDPVRWPNSHWRSVKVGWDESTAGERQPRVSLWEIEPLTTFPMYPSAFPLRLKRPWPSGLPSLHGGKDDDIGLNSSLMWLQDGERGIQSLNFQGFGMTPWMHQRCNSSILGLQPDMYQAMASAALQEMRAVDFSKQATSTVMQFQQHQNITNASAPLLASQVLQQMQPQSQQTLLQNLQETQNQNQTLYPFVQHQMQHCNSFHDQEQLQPRLLQQQEQEQLQSRPLQQQEQEQLHPRSLQQQEQKPQKQQIQQQQLSNQQIPNAMSTLSQFASTSQAQTLSLQKMASLCQQQNLPETIINRMSTSGVSPLHGILHPFSAEETSGLVSMPKTTPLIATSPWSSKRLAVESIPVLQSMQPEVKQLGSQINFSQNAVTVPPSSGRDCSLNQECGMDRQSNLLSSVNIDSSSLLVQNGMSNLRNFDNDTVSTLMPFVSTTGTDYALHQALTSSNCIEDSEFLQSPNSVGVMNPQNGTFVKVYKSGSFGRSLDITKFNSYPELRSELGRLFGLEGLLEDPLRSGWQLVFVDRENDVLLVGDDPWHEFVNNVSSIKILSPQEVQQMGKEGVDLLNAATNRRIPSHTSDEYISRQESRNLSNGMASVGSLDY
The following text describes a protein:
Function:
Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane.
Subcellular Localization:
Cell membrane. Cytoplasm, cytoskeleton.
Sequence:
MGEALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILHFRAPVRAFLPALRKVALTAQTGEQPSKIHRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQVSGRKQHLLGQFTLLFNPWSREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVIDLSLRLLSEDKQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQERALLNKRRGSVPILRQWLTGQGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYNEEGLQNGEVQRGRIWIFQTSTECWMTRPALPEGYDGWQILHPSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVKKEKMEREKDNGIRPPSLETANPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLALGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFHSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTVVAPELSA