lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probably transfers the 4'-phosphopantetheine moiety from coenzyme A (CoA) to a serine residue of a carrier protein domain.
Sequence:
MLPQPQIWLCPTDRPLIPGYQALLSSEEMARGERYQRPQDKQRFLTMRLALRILLARQLDCLPQQLQFTYGPQGKPELVDRERRSPWFNVAHSGNYGLIGLSTEGEIGVDLQIMLPKPHYLKLAKRFFAPQEVQQLESLEGEKRTKLFYQLWTAKEAFLKATGKGISGGLNQVIPDENLAKYQYLPDSGDTNHWRLSSQPLLADQGSNDNYWMAIAWCTNEVNQVESNYLPNIQPFQWPRNLDSLP
The following text describes a protein:
Function:
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Sequence:
MDGFEDTQFQAAPAASGEGFNDFAAAPASNGGAAPTVPPPLDDFFSGSTPAVPAPPPGDDAPPASEAVIAAAGSQGAEPFEVPVVAVEGAAADDGDAFFEHYTPTPKPVPAPEPEAADPRVEWRKQNAETLKKKDATESAAKTKVKDSAAAHLAKFYEVRTTTLTQRKANNRKSEAHQKEVEVPASGTPWEKVNALVNMNTSHTKDVSRYKAVLITCKAKNVPIRAAA
The following text describes a protein:
Function:
Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol. Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Endoplasmic reticulum membrane.
Sequence:
MEDLWKPLLDNTTLAALLQRLNDITPSQWCQAYYLFAAGAVVAVAAMPNEVSRRLVDYGARKVQSVKVSRSGSRSSEGKEENDTGRGTGSEAEVKAKANRVERGGDKNWLLSLTDTLTSYGQVPHSWFITFYVASMACSLLWFWQFAVDGRVLRVVTCSQASPTAKGGDERGGVSASSVTLGQVGLAWTMMFLQGSRRLYEDSLVHGKSKSTMWIVHWVLGLSYYLFTSVAVWVEGSGAILEYQSTGAIDYTMPSFKSLVGTFMFLYASVNQYRCHRHLAGLKKYSLPDLGLFRYLICPHYFCECLVYLSLAIVAAPQGELLNKTLLCALVFVVVNLGVTAAGTRKWYAEKFGSKAVETKWDMIPFIL
The following text describes a protein:
Function:
Suppresses SRC activation by recognizing and binding to active SRC and facilitating PTPN13-mediated dephosphorylation of SRC 'Tyr-419' leading to its inactivation. Inactivated SRC dissociates from this protein allowing the initiation of a new SRC inactivation cycle. Involved in reorganization of the actin cytoskeleton. In nonmuscle cells, binds to ACTN1 (alpha-actinin-1), increases the affinity of ACTN1 to F-actin (filamentous actin), and promotes formation of actin stress fibers. Involved in regulation of the synaptic AMPA receptor transport in dendritic spines of hippocampal pyramidal neurons directing the receptors toward an insertion at the postsynaptic membrane. Links endosomal surface-internalized GRIA1-containing AMPA receptors to the alpha-actinin/actin cytoskeleton. Increases AMPA receptor-mediated excitatory postsynaptic currents in neurons.
Subcellular Localization:
Cell projection, dendritic spine. Cell projection, lamellipodium. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Synapse, synaptosome.
Sequence:
MPHTVTLHGPSPWGFRLVGGKDFSTPLTISRINPGSKAALANLCPGDVILAINGESTECMTHLEAQNKIKGCMDYLLLSVNRTETKSWAPAAPEDGKAQAYRINIDSDSQVLRWGSAWGRRSAANETLFCFCGCSEPIMSTDRGQLIEVTSNPYLLTPGWTLRWNGIDVESDVYKMLQDPGEPAPAPKQSGSFRYLQGMLEAGENGEKTDRPAGPRNLKSPGSKLGGAISGLQMLPECTRCGNGIVGTIVKARDKLYHPECFMCDDCGLNLKQRGYFFIEERLYCETHAKERVKPPEGYDVVAVYPNAKVELV
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
Sequence:
MLQDAQDVFNLENHGRVREVGSQAVWSVSSGRRGHGVSQLRDGDLDTFWQSDGELPHRIDVQFGRRLSIQAVLINVCHDLDENFTPNVVSVSAGNDPHDMRTVGGVSMTRPSGWVLIETEDSEERPPRAFCLRLYVHINHQFGMDSRVRQMKVYTPAQETVVSTLPEEVTFSSLECRMFSRIR
The following text describes a protein:
Function:
Plays as essential role in regulating terminal differentiation.
Sequence:
MSQSDPLNVVSRILNKISKDNFQVLIDQLVSKCQLLDKNESTLFINNIFEKVVEEPSSSSYYIQIINKIQPIFQQNFSIGVGNKLVENFNKRYQILTDQINSNEETFDFNSSKQSFLNLCKFMGECYYTLPSSFLVDVVNNHLPQVTKETADDMTLQQLMEIEIIATSFTSAGKTIESMGGFSSKHENNKTHNNNNNNNNHDHDDDDHDEEDNENNYENTTSTTNNINNNNIQSRENDLHFKGIQKALEDATSVLSFLIENRQLLPPRVRFMVKNLFELKNNKWIIPKAINDDLNAQREVVKVATNHGKTISKSLSEKCDDDSTLNTIFWKSFFQALGIQNYKILRQLMLDDKSNISPSSTSPTIPLSPFLRRSMNITSPSQFNLNNCNNNNNSININNNNMDIDASFDLNDGLMESSSNNNNSNSQLQFSLSSSSGIKDNHNVPTIDLNTISSNNNQQINLPSGFLSPKVARSNSPSLSSVVKQPQSQQNNNNNNNNNNNNTTITTTTSSNNNINNNNNNNNNNKIKESPELSSAPDSNLSVIVSIIDSKIWTPQKEIWKKKIMNKIIPMKSILKKPQKIEILAAIWQNMCDNNYEYGSYLDLCLNLIKMDEGDISPLYSLDGGNVPPVKPYQQSAQPPPPPPSSSSSSAQQPPNEPVNPLLNKLKGPNRRSSMATLQMKPSGISEARRSSISVPFELNRRGSLSGDIPSYCPPAPKLKSTPTLKSTPAIVQNGGSITSTSSSSSSSSSSSSSTTKNIHPTSESKKQPIAKKHKPDLDSFKDVLISSLQDDFALKMFVKKRSLTTYMELLKDLYREFIIEIPLLLKCISLVHNGLYELTDEECTMLFDLEEMAQEQQNLEKQNDQQQNLLTQNNQIFQWKTNTWEEKPQTPPPPPTSYFDLGSDVFVL
The following text describes a protein:
Function:
Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells (By similarity). Potentially links obesity to diabetes (By similarity). Promotes chemotaxis in myeloid cells.
Subcellular Localization:
Secreted.
Sequence:
MKALCLLLLPVLGLLVSSKTLCSMEEAINERIQEVAGSLIFRAISSIGLECQSVTSRGDLATCPRGFAVTGCTCGSACGSWDVRAETTCHCQCAGMDWTGARCCRVQP
The following text describes a protein:
Function:
Required for normal growth in the presence of linoleic acid hydroperoxide (LoaOOH).
Miscellaneous:
MISCELLANEOUS: Present with 4530 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MKYIPPLNFSPVVSTDVSLYRSGYPMPLNYSFIKHQLHLKTIIYIGDKDRPLEEYQSFLESEKIKYYHIFMDSSRDEGIQERMNQVLHLVLDVRNYPILVHSNKGKHRVGVVVGIIRKLLQGWSTAGICQEYGLFSGGMKDGVDLEFITMFETNLKIPRNVIPGFAKHCLYLNELEAAEGSDDESGSESILTAKQPI
The following text describes a protein:
Function:
May play a role in a signal transduction pathway used during gastrulation. Required specifically for the ventral furrow and posterior midgut invaginations, where it is necessary for coordinating cell shape changes; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Subcellular Localization:
Cytoplasm.
Sequence:
MSGITLTKLTQERISIPNNNVITNGVENNIDSDTLSGTLTHLMEEHRTRVGAVTGPEAATTSTDGLISNGAERLRLQGSRLQTSRFACFRCCGNIITYLVRLRSTPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEYQSVIYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNSLDVPKFMEYAPPISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEESKNIFDTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRRSSSISRIYHHFTTAIDTRNINVVFNSVKDTILQRNLNALMLQ
The following text describes a protein:
Function:
Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.
Subcellular Localization:
Cytoplasm, cytosol. Cytoplasmic vesicle.
Sequence:
MNNALDLGDFLLSFPLCSLPELLLFQSLFSKKNKQKGSSCSLVLRNLCCNQQRTIIIPYVGTILGGLVPGELIVLHGSVPDDADRFQVDLQCGSSIKPRADVAFHFNPRFKWSGCVVCNTLEREKWGWEEITYEMPFQKGRPFEIVIMILKDKFQVSVNKKHLLLYNHRISLERIDTLGIYGKVQIKSIEFVSNSVQGAQPSSVGVTKINTENGEMPDGLQFGVPYVGKLVSALHPGCTVAIKGEVNKNPKSFTINLKSSDSKDIALHLNPRLKNKVFVRNSYLHDSWGEEEKEVTDFPFSPGMYFELIIFCDAHQFKVAVNGVHTLEYKHRFKQLEKINLLEVTGDVQLLDVRSW
The following text describes a protein:
Function:
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Miscellaneous:
MISCELLANEOUS: The porphobilinogen subunits are added to the dipyrromethane group.
Sequence:
MNFVIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVKDIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLRKGAKIGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGVILAVAGLKRVNLDHLITDYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHSTIGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGISLAEHILKD
The following text describes a protein:
Function:
Could act as a modulator of transcription.
Sequence:
MNGDDAFAKRPRDDDKASEKRSKAFNDIATYFSKKEWEKMKYSEKISYVYMKRNYEAMTKLGFNVTLPPFMCNKQATDFQGNYFDNDRNRRIQVERPQMTFGRLQRIIPKIMPKKPAEEGNDSKGVSEASGPQNDGKQLAPGKANTSEKINKRSGPKRGRHAWTHRLRERNQLVIYEEIRDPEEDDE
The following text describes a protein:
Function:
Catalyzes the formation of N-benzoylanthranilate, in the course of methoxydianthramide B, a phytoalexin. Phytoalexins are produced in response to infection by parasites, and are essential for the expression of disease resistance.
Sequence:
MEVSIKSSSMVKPIEPTCKVVFRLSEWDQTGIITHVPTVYFYKPSQEWFISSKSIIDTLKDSLSRVLVHFYPLAGRVQWIGQGRLELICNSMGVELIEAESSINLSDFASKTNLFENLVPFVDYNKPIHELPLVSGQITKFRCGGICLGVNISHILADGQSALHFMSEWARLARDEPLEMAPYFNPNILRAQELPMTLAPSNMHTEFITPPLLIGQQNNLDERRKITTVAILSLSKYHVESLKKVANEGPNGPNTYNYTRYEVVTSHIWRSACKAREHHREQPTCLGFSVDVRNRLHPPLPPNYFGNAILDVVASSRSGDIITLPLGFTCARIREAIDKFDDQYIWSNINFWKSLIDFSPFQDFHSRKSKDAPFYGKPNLGVISWLTLPIYGLDFGWGTEIYMGPGAHDSDGDCIMLPGPMDDGSVKVAICLQLAHMDAFKKYFFEDII
The following text describes a protein:
Function:
Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5) (By similarity). May play a role in the regulation of Na(+)-dependent phosphate cotransport, possibly via its role in diphosphoinositol pentakisphosphate (InsP7/PP-InsP5) biosynthesis (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSPAFRTMDVEPRTKGILLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRRFTPQYKAVLIFVRCADEFGASGNIETKEQGVVSVRFEEDEDRNLCLIAYPLKGDHGTVDIVDNSDCEPKSKLLRWTNKKHHALETEKNPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYSVEKKGNVSSQLKHYNPWSMKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGTGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLRRELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKEWPEVTLDSDAEDLEDLSEESADESAGAYAYKPIGASSVDVRMIDFAHTTCRLYGEDSVVHEGQDAGYIFGLQSLIDIVTEISEESGE
The following text describes a protein:
Function:
Required for formation of the mei-W68-mediated double-strand breaks (DSBs) that initiate meiotic recombination.
Miscellaneous:
MISCELLANEOUS: Despite weak sequence similarities, may correspond to the subunit B of a mei-W68/spo11-containing topoisomerase 6 complex specifically required for meiotic recombination. Retains some of the structural features of the ancestral archaeal Top6B subunit (AC O05207).
Subcellular Localization:
Chromosome. Note=Localizes to foci on meiotic chromosomes.
Sequence:
MDRTTVVPSPASTYCSFMGGSQHSPLRRSQRLIDKENRDLQKIPPKSLSPQLFGNTEDDYSELLLQQGKVVHLKPAAKLVPVRSSDNLVHLGSRDKVVPLKTSNRIVHLKPPYKIIHLKSLDEVEKTVKKKNNIQKEVHQRNSQRRSIQCTPKKRGRKPKQPAKKLQSRISTDQLGSTPSPSKLPAKYPAHFVHQLPPAEDSSCATRRRSLSAPAMQLSDLSLTPDEIQTPERRGEIVNKSPSDLDSDVSLNFSLSDSIGEIFGTKDISSILTMQRPRQYILLEEHLPTLATMLNVDLERLRCVLDITQGLSHEQILRFPIKHEEDELEVP
The following text describes a protein:
Function:
Core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The SCF complex associates with CDC34 as the E2 ubiquitin-conjugating enzyme. The functional specificity of the SCF complex depends on the type of F-box protein. SCF(CDC4) controls the G1-to-S phase transition; it directs ubiquitination of the phosphorylated CDK inhibitor SIC1 and of CDC6. SCF(CDC4) directs ubiquitination of GCN4. SCF(GRR1) directs ubiquitination of phosphorylated CLN1, CLN2 and GIC2. SCF(MET30) directs ubiquitination of MET4. SCF(DIA2) is specifically involved in the pheromone induced degradation of phosphorylated TEC1. SCF(MDM30) seems to direct ubiquitination of FZ01. Involved in the regulation of methionine biosynthesis genes.
Miscellaneous:
MISCELLANEOUS: Present with 377 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSETLPRSDDLEATWNFIEPGINQILGNEKNQASTSKRVYKILSPTMYMEVYTAIYNYCVNKSRSSGHFSTDSRTGQSTILVGSEIYEKLKNYLKNYILNFKQSNSETFLQFYVKRWKRFTIGAIFLNHAFDYMNRYWVQKERSDGKRHIFDVNTLCLMTWKEVMFDPSKDVLINELLDQVTLGREGQIIQRSNISTAIKSLVALGIDPQDLKKLNLNVYIQVFEKPFLKKTQEYYTQYTNDYLEKHSVTEYIFEAHEIIKREEKAMTIYWDDHTKKPLSMALNKVLITDHIEKLENEFVVLLDARDIEKITSLYALIRRDFTLIPRMASVFENYVKKTGENEISSLLAMHKHNIMKNENANPKKLALMTAHSLSPKDYIKKLLEVHDIFSKIFNESFPDDIPLAKALDNACGAFININEFALPAGSPKSATSKTSEMLAKYSDILLKKATKPEVASDMSDEDIITIFKYLTDKDAFETHYRRLFAKRLIHGTSTSAEDEENIIQRLQAANSMEYTGKITKMFQDIRLSKILEDDFAVALKNEPDYSKAKYPDLQPFVLAENMWPFSYQEVEFKLPKELVPSHEKLKESYSQKHNGRILKWLWPLCRGELKADIGKPGRMPFNFTVTLFQMAILLLYNDADVLTLENIQEGTSLTIQHIAAAMVPFIKFKLIQQVPPGLDALVKPETQFKLSRPYKALKTNINFASGVKNDILQSLSGGGHDNHGNKLGNKRLTEDERIEKELNTERQIFLEACIVRIMKAKRNLPHTTLVNECIAQSHQRFNAKVSMVKRAIDSLIQKGYLQRGDDGESYAYLA
The following text describes a protein:
Function:
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
Sequence:
MNSISNQTIPHQASRYQAAFSRLKAEGRGAFVPFVTLGDPSPELSLKIIDTLVQNGADALELGFPFSDPLADGPVIQGANLRALAAGTTPTACFELLAKIRAKYPELPIGLLLYANLVFANGIDAFYAKAQQAGVDSVLIADVPVEEAAPFIQAAKAHGIAPIFIAPPNADSDTLAKVSQSGEGYTYLLSRAGVTGADTKAGTPVEEILAKLQEFNAPPPLLGFGIAEPAQVSAAIKAGAAGAISGSAVVKIIETHQQDEVKLLAALGEFTRTMKAAT
The following text describes a protein:
Function:
Regulatory subunit of the ATP-dependent BRF-1 and BRF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template. The BRF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the BRF-5 ISWI chromatin remodeling complex. Chromatin reader protein, which may play a role in transcriptional regulation via interaction with ISWI (By similarity). Involved in positively modulating the rate of age-related behavioral deterioration (By similarity). Represses the expression of mitochondrial function-related genes, perhaps by occupying their promoter regions, working in concert with histone methyltransferase EHMT1 (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MESGERLPSSAASSTTPTSSSTPSVASVVSKGGLSTGVASLSSTINPCGHLFRTAGDQPFNLSTVSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLASFPGAEWWRTTDAHTRTGATFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDERELRIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTKAFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSVMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAESVQIKEEMFETSGDSLNCSNTDHCEQKEDLKEKDNTNLFLQKPGSFSKLSKLLEVAKMPPESEVMTPKPNAGANGCTLSYQNSGKHSLGSVQSTATQSNVEKADSNNLFNTGSSGPGKFYSPLPNDQLLKTLTEKNRQWFSLLPRTPCDDTSLTHADMSTASLVTPQSQPPSKSPSPTPAPLGSSAQNPVGLNPFALSPLQVKGGVSMMGLQFCGWPTGVVTSNIPFTSSVPSLGSGLGLSEGNGNSFLTSNVASSKSESPVPQNEKATSAQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQKHLDYITQACLKNKDVAIIELNENEENQVTRDIVENWSVEEQAMEMDLSVLQQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFTKLCKEHDGEFTGEDESSAHALERKSDNPLDIAVTRLADLERNIERRIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFKVS
The following text describes a protein:
Function:
Involved in glucosinolate biosynthesis. Hydrolyzes the gamma-glutamyl peptide bond of several glutathione (GSH) conjugates to produce Cys-Gly conjugates related to glucosinolates. The gamma-Glu-Cys-Gly-GSH conjugates are the sulfur-donating molecule in glucosinolate biosynthesis. Converts phenylacetohydroximoyl-GSH to benzylglucosinolate. Can use the GSH conjugate of the camalexin intermediate IAN (GS-IAN) as substrate. Required for the biosynthesis of camalexin, a pathogen-inducible phytoalexin with antibacterial and antifungal properties.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MVEQKRYALFLATLDSEFVKKTYGGYHNVFVTTFGDEGEHWDSFRVVSGEFPDEKDLEKYDGFVISGSSHDAFENDDWILKLCDIVKKIDEMKKKILGICFGHQIIARVRGGTVGRAKKGPELKLGDITIVKDAITPGSYFGNEIPDSIAIIKCHQDEVLVLPETAKVLAYSKNYEVEMYSIEDHLFCIQGHPEYNKEILFEIVDRVLALGYVKQEFADAAKATMENRGADRKLWETICKNFLKGRVPTN
The following text describes a protein:
Function:
RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. Binds to the 5' side of the stem-loop structure of histone pre-mRNAs.
Sequence:
MRNKSEIQPLSLKDSKSEIQPLAGVRILVAEKYSIISLVFYTLFFFFFFFLFFAFLPFLGPLLRICFLRKEVCEESLSSRIEMVSVGVSTEPCRARWEVETDKTILQRRQKQIDYGKRTPGYQSFLQQVPKAQRLPGLHPQTPNKNRRYSRRSWDAQIRQWRRALHSWDPPTSLCRWGMENLLEPMDSSPLQPSGNLDGDQKGTQLADLVAPASSLSWICEEDPHHWLYVLADYNYLSQT
The following text describes a protein:
Function:
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKTGKVENLIQNAPEKPGVYLFKKGNRPIYIGKAKNLKKRLLQHLKASEYDSKERAIISNSDNLEWIVTRNEYEALVLEIDLIQQYKPRYNVLHKFGGGYPMLLLTKDEYPTIKVVRGTEHEGELFGPFLQSKKAYKVKKLIHNLFKLRTCDPLPKRSEPCMDYHLGLCSAPCCGFVSKEEYELAVSSARALLTGEVAEVLPKLYEKIEEFSKELMFEKCAHIRDQIIALENLAKGQAVSALPFREGDIFYKFGSRLGLLLVRSSKLVSKEIFDLESDEEVEEVILGYYYSNYVPRKVITNFELSEEVKEWIRNRAKGEVEFSGEIPKELKEVLEENLGEGINEEVLKKEFAEKLGMPVPRVIEGFDISHFYGEDIVGSCVVWKGGKMSKKDYRRYKVKTISRIDDYLALEEVLTRRAKRILKGEVEKPDIWLIDGGKGQLNVGIRVKKRTGLDVKVFSLAKEEEIIYTEDGREIRLKENPILYRVFGEIRDEAHRFALSYNRKLREKRYMEDILSKIKGIGEQKKKIIYKNFETLYDFIEAKDEELRRLGINPSLKQEVKKWLS
The following text describes a protein:
Function:
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
Sequence:
MYLQFCDQCKQYTLKQKCPRCGGQTRSAHPARFSPEDKNSAERIQTKAKFNLLPYQQPDIEY
The following text describes a protein:
Function:
Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
Subcellular Localization:
Nucleus.
Sequence:
MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL
The following text describes a protein:
Function:
Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
Sequence:
MAFSGALTLTDLNDYLGPSQACIKPVQAADVPSQDHSDVSALAASASTHIAIDHDGAYYESSTPPSSSLSAADSRPRQRTKLETAQISLNDCLACSGCVTSAESVLITMQSQDEMRRAIAELNQSNANKLVVASISTQSLASLSAKYTFQHPQPSSSRSASTSTLPLRVLLHRISYFLKTVFGFDHVYDTTFARHIALKEHQREFFQRRENARKRAKLSNAPADDDDRLHPDQVDGPTLPMLASACPGWICYAEKTHGELLPYISTTKSPQQVAGVIAKRFLPERLGLLAPSAPDQPSIYHVTVMPCYDKKLEASRPDFYDDITGTKEVDCVLTTGELDKLMLDEAFDICTPVPGEQEAIQESIAELSLQQAFNTPNPDVGSASVSMMPRLPRLPQLLDQPGSSSGGYLFLLMRAVWLDWISVHWDSLPLSVREQGILPKLDVRVIRTTDFTEFVLRAPTQLVEPCNDDTSQSSILFRGAQCYGFRNLQNLVRKLQKQTGVRNTRGAAARLVDADGNAIGAAAARNRASSAKARARGRGGMMRRARAGAAAVVKSSPLNPDAEAVDVTQLQLSTAHEEDERGYDYVEVMACPSGCVNGGGQIRPPTQSDVDVTRSSTTVDNHATDPEGYTKGGWAADQAGDHDGLELMLNKTCSNKTSAVPDEADEEKEVRGWQGTSKEWVRRVEEAYWQDSSVAQTRVTVAAVNRAVDQGGANDSGSSTPTLVGSGANTPLSSSNAKSIRVEDHQRLLESLAVSNAERAQRTRVVKLGGDAMAYADVLAELVVNELCLLAAPAGDALALDSARDKLFRTQYRAVQDEAVNGLAVQW
The following text describes a protein:
Function:
Involved in the assembly of the cytochrome c oxidase complex.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MASPTSLPPPAPRPTAWEALQSFNLNDSLQDRFARVPSQRKALMFGMAGGTCIGGLRFISTRRGWSSANWGVYSFVFLSSISYYQLSQKRQTEVEQIQQVVTKMNQVKPSPKLTANLASEGERLTEEKSESTGDQNLNKKKSWLW
The following text describes a protein:
Function:
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
Subcellular Localization:
Nucleus.
Sequence:
MATSPAEFDDIDEFDEFGLDDHALLQLDLIEHNLASNATQLCPAPRSSSQTKSAPAPPCIQKLSSLRKTTHARGPAALQPPATNGSTTRIDPAATLAVATTSRRPMQRVRSTDSHASTQLASSGGTRQMNLFGKPVTSTQTRSAKLVSSSPGHIVISSQTAPTAANHSTAPDNINASPSYRPPWQQKVGTKTWDREAYLHRENAKNRDKEAIDVDAFDSSSPKGNPKLERERDWDAESEFVNVLPPEPLDSRRQLAPVQSQKCKIDLEAAKTWIYPTNMERRDYQYNIVQKALFNNVLAALPTGLGKTFIAAVVILNFFRWYPDGKILFLAPTRPLVDQQKTACHRICGLPWDCAIDLTGNTAGSRRGDYWATKRIFYMTPQTFENDLREKRCDPRDIVCVVIDEAHKARGKYAYGNVIGRIMEVNPHFRVLALSATPGKDSESVQEVVDQLHINQIEIRTEEAIDVQRYMFRKREEIVNVTLGKDLNLVKEKWAKLMQTQMDPLMKAGLLHNQDPVLLHPFAVNSMMKDRRRAAILRENRWLQANVRELSHMALSMQYLMEQSPTMFYSRLKERSMGYNTKGKQTSSAKQQMYANSNTTFIEIIHDLEVMQDHKGRILHPKMLKLRNVLIEHFDAFKADQVHNAEAFEVSGHDVLGNTPTSGEVANLESSSQADTRAMVFCSYRECCDEIVGFLNESGFKATEFVGQSKSRSGKKGMSQKDQERVIADFKKGIYNVLVATSIGEEGLDIGSVDLTVCYEAVKDSIRMLQRIGRTGRKREGKIAVLVSEGREQHNWQHSKNNYKAVQKEVDSRMHVELFDDVDRMVPDHISPRPVLKEVEQPEFEPSMISNDKAIKAPRATKVAKPKKDPKRNMPEGGDIIEGFRKASTLTKRKQRSGSHDVSHVNDADAVGPLNETHSQKMLRLLTLPQDELEPQSEKENLSLKFRSSKDKARPSTQRIIASSPPSSPPFSPPPSFRWPATSLGVGPASDGFQTVGVPSASSSPLALVAGGGVTRGKKLGVGPMGSGRSSTSSGILSLRKSDDAIDSVSAWYGHSKSQDQSRLETKSPRSRGIAQAVTTLNDDDDDDDEFADLTMDMSMENAISRIEQEATYKPDLHSPNPSRIEAQISMESNNRLKDGHEQLEPILLSPPSPRRAISREKKAHPIIQAIIDEEEEKVLAKQRQEKTDTRSKAQELQGKGLSLMGPPDSVPRRAGGWRSKRVIRESPDIDSSGVLSKHLDYEVDDDTALSSPIKGPVKRRGRLQKASSSSKAADDVDTSPTAVKGRTRVRGKVRIADDSDDERDAETRRLQSKKRNEMAARQRGGGIKKRKITNSPTSRALFQYEAERSTDEEVHGERDEDDSGLGSSAEDDSDREAVGDFVPTQAPRGYHQQSIYLQSMLSQAAPPEFQRLRHAPFPGVGGRFGEPVTPSRPAWRPTSAQPVSSESRNAARMQMASDDMYSEDSFVVNDEDDIIYDSEPDGLPDSSQL