The following text describes a protein:
Function:
A probable inverse autotransporter, it may be involved in biofilm formation and cell adhesion. May bind peptidoglycan via its LysM domain (By similarity). Upon overexpression shows increased mature biofilm formation.
Miscellaneous:
MISCELLANEOUS: 'Inverse' autotransporters have an N-terminal translocation domain followed by the passenger domain, as opposed to 'classical' autotransporters which have N-terminal passenger and C-terminal translocation domains.
Subcellular Localization:
Cell outer membrane. Note=The passenger domain (approximately residues 401-2641) is exposed on the cell surface, and may be processed and released to the extracellular milieu.
Domain:
Has a signal sequence, a Lys M domain, an inverse autotransporter domain (residues 125-400) predicted to form a 12-stranded beta-barrel, followed by the passenger domain with an invasin 3 domain (residues 513-605), 17 Big-1 domains and a C-type lectin domain (resides 2538-2638).
Sequence:
MGIKLRRLTAGICLVTQLAFPMAAAAQGVVNAATPQPVPAQIAIANANTVPYILGALESAQSVAERFGISVAELRKLNQFRTFARGFDNVRQGDELDVPAQVSEKKLTPPPGNSSDNLEQQIASTSQQIGSLLAEDMNSEQAANMARGWASSQASGVMTDWLSRFGTARITLGVDEDFSLKNSQFDFLHPRYETPDNLFFSQHTLHRTDERTQINNGLGWRHFTPTWMSGINFFFDHDLSRYHSRAGIGAEYWRDYLKLSSNGYLRLTNWRSAPELDNDYEARPANGWDVRAEGWLPAWPHLGGKLVYEQYYGDEVALFDKDDRQSNPHAITAGLNYTPFPLMTFSAEQRQGKQGENDTRFAVDFTWQPGSAMQKQLDPNEVAARRSLAGSRYDLVDRNNNIVLEYRKKELVRLTLTDPVTGKSGEVKSLVSSLQTKYALKGYNVEATALEAAGGKVVTTGKDILVTLPGYRFTSTPETDNTWPIEVTAEDVKGNFSNREQSMVVVQAPALSQKDSSVSLSTQTLSADSHSTATLTFIAHDAAGNPVIGLVLSTRHEGVQDITLSDWKDNGDGSYTQVLTTGAMSGTLTLMPQLNGVDAAKAPAVVNIISVSSSRTHSSIKIDKDRYLSGNPIEVTVELRDENDKPVKEQKQQLNTAVSIDNVKPGVTTDWKETADGVYKATYTAYTKGSGLTAKLLMQNWNEDLHTAGFIIDANPQSAKIATLSASNNGVLANENAANTVSVNVADEGSNPINDHTVTFAVLNGSATSFNNQNTAKTDVNGLATFDLKSSKQEDNTVEVTLENGVKQTLIVSFVGDSSTAQVDLQKSKNEVVADGNDSATMTATVRDAKGNLLNDVKVTFNVNSAEAKLSQTEVNSHDGIATATLTSLKNGDYRVTASVSSGSQANQQVNFIGDQSTAALTLSVPSGDITVTNTAPQHMTATLQDKNGNPLKDKEITFTVPNDVASRFSISNGGKGMTDSNGVAIASLTGTLAGTHMITARLANSNVSDTQPMTFVADKDSAVVVLQTSKAEIIGNGVDETTLTATVKDPFDNVVKNLSVVFRTSPADTQLSLNTRNTNENGIAEVTLKGTVLGVHTAEAILLNGNRDTKTVNIAPDTSNAQVTLNIPAQQVVTNNSDSVQLTATVKDPSNHPVAGITVNFTMPQDVAANFTLENNGIAITQANGEAHVTLKGKKAGTHTVTATLGNNNASDAQPVTFVADKDSAVVVLQTSKAEIIGNGVDETTLTATVKDPFDNVVIDLPVTFSTNPADTQLSQSTSNTNDSGVAEVTLKGTVLGVHTAEATLPNGNNDTKTVNIAPDASNAQVTLNIPAQQVVTNNSDSVQLTATVKDPSNHPVAGITVNFTMPQDVAANFTLENNGIAITQANGEAHVTLKGKKAGTHTVTVTLSNNNTSDSQPVTFVADKTSAQVVLQISKNEITGNGVDSATLTATVKDQFDNEVNNLPVTFSTASSGLTLTPGESNTNESGIAQATLAGVAFGEQTVTASLANTGASDNKTVHFIGDTAAAKIIELTPVPDSIFAGTPQNSTGSVITATVVDNNGFPVKGVTVNFTSRTNSAEMTNGGQAVTNEQGKATVTYTNTRSSIESGARPDTVEASLENGSSTLSTSINVNADASTAHLTLLHALFDTVSAGETTSLYIEVKDNYGNGVPQHQVTLSVSPSEGVTPSNNGIYTTNYYGNFYASFTATKAGVYQVTATLENGDSMQQTVTYVPNVANAEISLAASKDPVIADNNDLTTLTATVADTEGNAIANTEVTFTLPEDVRANFTLSDGGKAITDTEGKAKVTLKGTKAGAHTVTASMAGGKSGQLVVNFTADTLTAQVNLNVTEDNFIANNVGMTTLQATVTDGNGNPLANEAVTFTLPADVSASFTLGQGGSAITDINGKAEVTLSGTKSGTYPVTVSVNNYGVSDTKQVTLIADAGTAKLTSLTSVYSFVVSTTEGATMTASVTDANGNPVEGIKVNFRGTSVTLSSTSVETDSQGFAEILVTSTEVGLKTVSASLADKPTEVISRLLNASADVNSATFTSLEIPEGQVMVAQDVAVKAHVNDQFGNPVAHQPVTFSAEPSSQMIISQNTVSTNTQGIAEVTMTPERNGSYMVKASLANGASIEKQLEAIDEKLTLTASSPLIGVNSPTGATLTATLTSANGTPVEGQVINFSVTPEGATLSGGKVRTNSSGQAPVVLTSNKVGTYTVTASFHNGVTIQTQTTVKVTGNSSTAHVASFIADPSTIAATNSDLSTLKATVEDGSGNLIEGLTVYFALKSGSATLTTLTAVTDQNGIATTSVKGAMTGSVTVSAVTTAGGMQTVDITLVAGPADASQSVLKNNRSSLKGDYTDSAELHLVLYDISGNPIKVSEGMEFVQSGTNVPYVKISAIDYSQNINGDYKATVTGGGEGIATLIPVLNGVHQAGLSTTIQFTRAEDKIMSGTVLVNGANLPTTTFPSQGFTGAYYQLNNDNFAPGKTAADYEFSSSGSWVDVDATGKVTFKNVGSKWERITATPKTGGPSYIYEIRVKSWWVNAGDAFMIYSLAENFCSSNGYTLPLGDHLNHSRSRGIGSLYSEWGDMGHYTTEAGFQSNMYWSSSPANSSEQYVISLATGEQSVYEKLGFAHATCYKNL