lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal domain of the MobA region determines nucleotide recognition and specific binding, while its C-terminal domain determines the specific binding to the target protein.
Sequence:
MFTHLDENQQPRMVDISQKVAGDRRAVAQCIVQLPKAIKDYLTGQEIFLKKGPVIQTAIIAGTMAVKKTADLIPFCHTLPIHGCKFDINIVYQKRDYLEIFLQCAVNTNYKTGVEMEALCGVSVAALTIYDMCKSISSEIIIKNTKLIEKTGGKADVSQTPLYGLVLTGGKSRRMGKDKALINYQGQPHGQYIYDLLAKYCEQVFLSARPSQWQGTPLENLPTLVDRGESVGPMSGILTALQSYPGVNWLIIACDLAYINSTMVEKLIAQARQDLVATCYENADQGFPEALCGFYTPLALQLFTKAQNIGLHCPVKILQMADCQLIKPDNLFDIANINSPEDYGQIN
The following text describes a protein:
Function:
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins.
Subcellular Localization:
Nucleus.
Sequence:
MTMEQEIEVLDQFPVGMRVLAVDDDQTCLRILQTLLQRCQYHVTTTNQAQTALELLRENKNKFDLVISDVDMPDMDGFKLLELVGLEMDLPVIMLSAHSDPKYVMKGVKHGACDYLLKPVRIEELKNIWQHVVRKSKLKKNKSNVSNGSGNCDKANRKRKEQYEEEEEEERGNDNDDPTAQKKPRVLWTHELHNKFLAAVDHLGVERAVPKKILDLMNVDKLTRENVASHLQKFRVALKKVSDDAIQQANRAAIDSHFMQMNSQKGLGGFYHHHRGIPVGSGQFHGGTTMMRHYSSNRNLGRLNSLGAGMFQPVSSSFPRNHNDGGNILQGLPLEELQINNNINRAFPSFTSQQNSPMVAPSNLLLLEGNPQSSSLPSNPGFSPHFEISKRLEHWSNAALSTNIPQSDVHSKPDTLEWNAFCDSASPLVNPNLDTNPASLCRNTGFGSTNAAQTDFFYPLQMNQQPANNSGPVTEAQLFRSSNPNEGLLMGQQKLQSGLMASDAGSLDDIVNSLMTQEQSQSDFSEGDWDLDGLAHSEHAYEKLHFPFSLSA
The following text describes a protein:
Function:
Required to maintain a pool of extrasynaptic AMPA-regulated glutamate receptors (AMPAR) which is necessary for synapse development and function. Regulates AMPAR function and synaptic transmission during development but is dispensable at mature hippocampal synapses. Plays a role in regulating basal phosphorylation levels of glutamate receptor GRIA1 and promotes GRIA1 and GRIA2 cell surface expression.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein. Synapse.
Sequence:
MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPIPPPQTAPSSHHHHHHHYHQSGTATLPRLGAGGLASAAASAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAPTAQAPGFVVPTHAGAVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGPGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP
The following text describes a protein:
Function:
Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P). Involved in the control of PI3P-dependent signaling and in the maintenance of endosomal system integrity.
Miscellaneous:
MISCELLANEOUS: Present with 1080 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MEYIKIAKVSNVVLHRRGTATQGTLHLTTHHLIFESPQLSTEFWFPYPLIYGVHKNPGSTLLSKLTSTNQIQLEGTDSQNYKLYQGKDLWSFVNIKVIGKDYAVFSLDFGGDLHLQARKVYDSILNLTVLSNITQLYAFIYISNNLERKLPSPDSWDIYDPIKEFRRQGLDSKDETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQDEKLVWESFNSFCNKDIRRTKHVIVDARPRTNALAQMALGGGTENMDNYNFFLADNNMGVDKSLKLPTVTRLFLGIDNIHIVSNTAAYMTEVICQGGDLNLPLEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDIRFHDNTMHSNFNDVDTNGDDLDIGVNTQDDYAEDDEGGEDETNLINLSRISKKFNENFKLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQRKRSGMNEHDQNLEEEEKVEWISPDLKKVQWWWQLYGRKDSEMNDELRHKRDSVPISVDKKSKEHSNSDGGKGLNLSIFGFDMFNRK
The following text describes a protein:
Function:
Casein kinases are operationally defined by their preferential utilization of acidic proteins as substrates.
Sequence:
MRLLLLLPPPPPTLPLIVWRHLHLPCTIGALSYLTVDCRYTNGSSFDPHLDPYSLDEEISLRIVMSKACVYTDVNMIRPKEYWNYESLNVEWGEQDDYEVVRKVERGKYSEVFEGINMNSNGKCVIKILKTVKKKKIKILQNLCEGPNIVKLLDVVRDEHSKTPSLIFEYVNSIDFKVMYPTLTDYDIRYYIYELLKALDYCHSQGIMHKDVKPHNVMIDHELGKLRLIDLGEQDDYEVVRKVERGKYSEVFEGINMNSNEQCVIKILKPVKKKKNLYGGPNIVKLLDVVRDQHSKTPSLIFEYVNSIDFKVMYPTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELGKLRLIDWGVSLSFIILEKSITSVWPQGTLRDPDFVDLQDYDYSLDMWSLGCMFAGMVLGTDELNAYLNKYQLQLDAQLEALLFLPRNLRILRIVSNHIIHSAETQVPSVALYTTLHLESDLIASYAYS
The following text describes a protein:
Function:
May be tethered PEX4 to the peroxisome membrane and may be involved in a late step of the matrix protein import. Does not play a role in the biogenesis of the peroxisomal membrane.
Subcellular Localization:
Peroxisome membrane; Single-pass membrane protein.
Sequence:
MAESSSPSPTEEIVRLIKRLSAYVAFKMSSLFSTTSIRNLDSRSIGAIAGLAIAVIFTWRAIRTPGEQRQRRQPKRRIHNAETSSAAAAASQSNLASSVAPEVSSPREDNAVQDVVDQFFQPVKPTLGQIVRQKLSEGRKVTCRLLGVILEETSPEELQKQATVRSSVLEVLLEITKYSDLYLMERVLDDESEAKVLQALENAGVFTSGGLVKDKVLFCSTEIGRTSFVRQLEPDWHIDTNPEISTQLARFIKYQLHVATVKPERTAPNVFTSQSIEQFFGSV
The following text describes a protein:
Function:
Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
Subcellular Localization:
Cytoplasm.
Sequence:
MVSVNIEAKKIVDRMIEGADDLKISVDKLENGSTVIDCGVNVDGSIKAGELYTAVCLGGLADVGISIPGDLSERFALPSVKIKTDFPAISTLGAQKAGWSVSVGDFFALGSGPARALALKPAETYEEIGYQDEADIAVLTLEADKLPGEDVTDKIAEECDVSPENVYVLVAPTSSLVGSIQISGRVVENGTYKMLEALHFDVNKVKYAAGIAPIAPVDPDSLKAMGKTNDAVLFGGRTYYYIESEEGDDIKSLAENLPSSASEGYGKPFYDVFKEADYDFYKIDKGMFAPAEVVINDLRTGEVFRAGFVNEELLMKSFGL
The following text describes a protein:
Function:
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates (By similarity). Promotes starvation-induced muscle atrophy.
Sequence:
MANHAKLVDQEIYRSPVDDFELNYQEYLNDDDDDKQEAPVAVSKAPKGKGSNHGLGCRMKGLFDGFGGTDLKTIMRHLRRRRPKSGQALTNFMLSGNMEKVVDQHVKDFVHHFGRINPENGRIMGALRGNDFFNFGGLHNNLGNTGKVYLDNLMKGKCGKKRKVHKFKPIVVEELDFGAPKPAVPATPKAPVAPVAPVIPAPAVTPQKPKVDEPTYADSVSDFGLDFETEREKCLRNKTLFEDPEFPATAASLYYRTPPRDRIIWKRPGEIIANPQLITQGESRFDVKQGALGDCWFLAALANITLYDALFYRIVPPNQSFTENYAGIFHFQFWHYGKWVDVVVDDRLPTVNNQLYYLHSADNTEFWSALVEKAYAKLHGGYENLDGGTTAEALEDFTGGLTEYFDLRKSEKAAVLAALVKGMEMGSLFGCSIDADANIKEAQLRNGLVCGHAYSITAIHSITYYGEDTTLLRLRNPWGNEKEWNGAWSDGSSEWSKIDEATKKQIDVQFARDGEFWMSFEDFFSNFTQMEVCNLTAEIFDEIAEMTGVNRATETVEEEHQWHEIMEDGEWSSKKGTAGGCNNNPSTYPKNPQFSTFFTAPQSSIEADGNVTVIVAVLQKYRRELRSKGKDVLPIGVSIYSLGAEGTARSPLTAQFFSQNRPIARTTVFVNTREVTVRFRVPPGQYVIVPCTFDAYDDAEFLLRVYANGTLKSSLL
The following text describes a protein:
Function:
Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane.
Sequence:
MFRMKSMRSFMFLICPVMVLVFFYYSSGRLQLKNSVQKSLYDKQGFLLKLDKKLPLELQYKYGNLSKGECKQGFAQAKMTLIYPKFSKPAPMFLDPNYKRLSKISSYPPPFGVRTQERIIDNILAATRSYSLGPELDSIPCKKCIIIGNGGILFNKSLGTKIDQYDVVVRLNEAPVAGFEKDVGSKTTMRITYPEGAIQRAERYEKSSLFVLSAFKSNDFKWLRHMVYKDRLTPGGPLTVNQIQTDAFETCGPEYSLSWRMDGFWKSVARVVPRAPQDMRILNPYFIQEASFRLIGLPHNNGLMGRGNIPTLGTVAITMALHNCDEVAVAGFGYDMNTPHAPLHYYEKLRMSAIKESWTHNISREKEFLRKLVKAGVIEDLTHGI
The following text describes a protein:
Function:
Probable RNA-binding protein that plays a role in meiosis and vegetative growth.
Sequence:
MELESKESLSADMPSLLRRSAEAFNGGSEYRSATDLSIFSSSLPTLFHEKLNMTDSDSWLSLDDNSPNLNKLVMGNSEKDSLEDAEPHSLEILLPEDENELLPGLIDELNFSGLPDELEDLDVFCTGGGMELDAESQRDAASSFVTRKRSNTSFRVSVEHPNGEHPSRTLFVRNINSSIDDSELTALFEPFGEIRSLYTACKSRGFVMISYYDIRAAHAAMRALQNTLLRKRTLDIHYSIPKENPSEKDMNQGTLVIFNVDSTVSNDELLKLFGAYGEIREIRETPNRRFHRFIEYYDVRDAEAALKALNRSEIGGKCIKLELSRPGGSRRVSVPSTSQDMDRHEVSSFLASQVANSPPGNWPIGSPLKGSPTHAFPRPPGLGIIRPFNRDNMPGLASVLPGQTSSFHGFSPVSNDQGLLNHPNQTILNNALMHNVSYGQPHSLPEHIGGGISNSMRFVAPPQSSGFGTSSDNSYRWGSPPQHMNYPGASSSSSSPTERPFAVRHGFPFAERQVSLLGKYQHHVGSAPSSTHFNTYTGPSEVSSLIPLGFGDMGINKSYINPHGKANLGVSLQGNHNKQDFSGFGMSSLPFGGSRGHEPFAEQGRIQHIDGGQYHIDLDRIATGDDTRTTLIIKNIPNKYTYKMLVAEIDEKHKGDYDFLCLPIDFKNKCNMGYAFVNMVSPLHIVPFQQTFNGKIWEKFNSGKVASLAYAEIQGKSALASYMQNPSTMEDEKQLFPEVSHHNDEGQDSKDQDRRFSSIWNIAAPDSDWSYTMDVIENPRKNIDSKNFVQESS
The following text describes a protein:
Function:
May be involved in rRNA-processing and ribosome biosynthesis.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MVLKSTSANDVSVYQVSGTNVSRSLPDWIAKKRKRQLKNDLEYQNRVELIQDFEFSEASNKIKVSRDGQYCMATGTYKPQIHVYDFANLSLKFDRHTDAENVDFTILSDDWTKSVHLQNDRSIQFQNKGGLHYTTRIPKFGRSLVYNKVNCDLYVGASGNELYRLNLEKGRFLNPFKLDTEGVNHVSINEVNGLLAAGTETNVVEFWDPRSRSRVSKLYLENNIDNRPFQVTTTSFRNDGLTFACGTSNGYSYIYDLRTSEPSIIKDQGYGFDIKKIIWLDNVGTENKIVTCDKRIAKIWDRLDGKAYASMEPSVDINDIEHVPGTGMFFTANESIPMHTYYIPSLGPSPRWCSFLDSITEELEEKPSDTVYSNYRFITRDDVKKLNLTHLVGSRVLRAYMHGFFINTELYDKVSLIANPDAYKDEREREIRRRIEKERESRIRSSGAVQKPKIKVNKTLVDKLSQKRGDKVAGKVLTDDRFKEMFEDEEFQVDEDDYDFKQLNPVKSIKETEEGAAKRIRALTAAEESDEERIAMKDGRGHYDYEDEESDEEESDDETNQKSNKEELSEKDLRKMEKQKALIERRKKEKEQSERFMNEMKAGTSTSTQRDESAHVTFGEQVGELLEVENGKKSNESILRRNQRGEAELTFIPQRKSKKDGNYKSRRHDNSSDEEGIDENGNKKDNGRSKPRFENRRRASKNAFRGM
The following text describes a protein:
Function:
Multicopy suppressor of the HtrA (DegP) null phenotype. It is possibly a protease, not essential for bacterial viability.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRVNNLSEQYKEMKEELAAALMDSHQQKQWHKAQKKKHKQEAKAAKAKAKLGEVATDSKPRVWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQRLRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENTEEGREKFREELNETHQLFKDFVKRMRPSLDIEQVATGEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKRLIDRFTGSAAESADRLLLRWWQRGQKPLM
The following text describes a protein:
Function:
Could regulate proteolytic events associated with testicular germ cell maturation.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MGARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLLFFPLLWALPLLGPV
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MLNNSDTTTPPPQIIQIPPQVPQQRLSFSVPIKAQVSSFPNTTTVAAQTARRVFKILFYLHLFLVAALVTFLTIYGLVSDSHTHHFHPKKWYPPLLASTACAGIVGFTWQWITASHSTRVVRLVFWLSPLLTCAMGIMFVCIGTAVSLAVGVIALVCALVQSLYFCWVNPRFEYATKILSVSVAFPPNRTQGLTLYSILIGILYCCFLLAGIGGARAIENRTQLAEFFIFLILLSLGWTMQFLKNAMYVTISRVKYMHFAGGVDMDTRVAVCDTIKHLTGSVSMGSILVPVIVLFRGFARTTSLVGGDTDEFMFSCVSCYMGVASLLVVRGNRWGFVHVGVYNKGFVQASCDTWEMFIRVGLEQLIDLDLTGAFCFLSGVGTGAICSLVSGIWSIVMHKSYATEVSIYAFLIGYFMCRLAIAWVQACVSAYYVAYAENPQSTQFDSTIPIRLEQLNRSQALQIFRANNLS
The following text describes a protein:
Function:
Probable transcriptional factor. Binds to the promoter of the SQUAMOSA gene.
Subcellular Localization:
Nucleus.
Sequence:
MECNVKWMMFGSKDPKTDSGSFNFSGFDTVGVYDFDDVDPTSDSKPSNFTFHVEKSIVKLSTTSPPMDAYDGPFKLGKRTFESNSGESSVDLPSFSISPISSLIAPKKTKFSTHNPLIPHCQVDACNLDLSSAKEYHRKHRVCHTHSKCPKVIILGVERRFCQQCSRFHSLSDFDENKRSCRRRLSDHNARRRKPQQETIQFNSTRLSSLFYDNRQSMNLVFNNDPLVHSKPTADSTWETSEVSKFTLTRGLTLKPYKADSINGQSLVGGVKLSGTTEMRNNASNLYSVSNGTTAEVLSQGVKETTFSLNMGVAPELPRALSLLSNENEFISIGHSTHVNQIIIPEQVMHAIPQSLPFESTEHWQAETTSIQSTHSYFGCEWSQW
The following text describes a protein:
Function:
Shell component of a type 1 encapsulin nanocompartment. Assembles into proteinaceous icosahedral shells 24 nm in diameter in the presence and absence of its ferritin cargo protein. The center of cargo-loaded nanocompartments is loaded with iron. The empty encapsulin nanocompartment sequesters about 2200 Fe ions while the cargo-loaded nanocompartment can maximally sequester about 4150 Fe ions. Does not have any detectable ferroxidase activity.
Subcellular Localization:
Encapsulin nanocompartment.
Sequence:
MNDLMRDLAPISAKAWAEIETEARGTLTVTLAARKVVDFKGPLGWDASSVSLGRTEALAEEPKAAGSAAVVTVRKRAVQPLIELCVPFTLKRAELEAIARGASDADLDPVIEAARAIAIAEDRAVFHGFAAGGITGIGEASAEHALDLPADLADFPGVLVRALAVLRDRGVDGPYALVLGRTVYQQLMETTTPGGYPVLQHVRRLFEGPLIWAPGVDGAMLISQRGGDFELTVGRDFSIGYHDHDAQSVHLYLQESMTFRCLGPEAAVPLRGLSQAATKA
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MVNHNNDDRTTDVDSHLRQKEQDKLLFHDFLGSKTETLASTSMADHSLPLDKAVKLAMTSASSVGGRGGLSSTSDLVERQGSGGGNHLDGRQLFGPRSEVSGSIMSNRFSGTKRSNSDSQFTSQEHPETLHWSKMLRNGPGSLSMNMNHMANQSPRGGGQISHLLHQLSSSRFKDENVGPSVISQTAADESSRTGMKGPGIMSHFTMPNPSKVECFAPSSTGNRKELTSSTKQMTIFYGGQAHVFDDVHPNKADVIMTLAGSSGGSWSTDLSHKPKTKNNTSDGPYKLSQMYEGGSSRETPFLSSEFRARPGHQATSSACQRIFTQPGREHQGSIISRGRETRDLVHVSDPEKKPRD
The following text describes a protein:
Function:
May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal.
Subcellular Localization:
Nucleus.
Sequence:
MLERKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEAVLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSHPQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRKQPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAARDSQAEPTQPEQAAEAPAEGGPQTNQLETGASSPERSNEVEMDSTVITVSNSSDKSVLQQPSVNTSMGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGEKKPYECTLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin Rv0910.
Sequence:
MGILDKVKNLLSQNADKVETVINKAGEFVDEQTQGNYSDAIHKLHDAASNVVGMSDQQS
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MGEKRKITSGEEAPERPQKAPRLDVLAEAGTESSAAAALLELSESPSAGKVEVAMSHSTSEIERCEHLLLDSEDLDMLVFDIKAGEMLWTCQSYVCSHRGSSVGGKAMRMVCLDCHSTFCTEHAQLHAKLTHHWVALVYDNPYVGYCYLCECVLKLGEDKWKEDDWEMATSKGTDEQGMVASNTKDEQRIVAGDDVCGYIIRGMPNLGSTCYMNAVLQCLLALGKLRTMILRPDARLGTIGQYLQQLFVETSSGNDATCLLNPRMLLHCMRMYNQEFWGNRMQDSHDFLTSLRDALDEEVKELNRLHCMQGGAVFPTIGQLIFKVQMCQTVSCKSCLNSAVQHVEFDDLQAAVAQPSKGPPARSVAPAPRITSPRSPRKHRKKLFQQSDKNDGEKIQTIPGSGDSQIPGSELGDVTMEKNPKPLQVDSNEAKDVVHDHFKTQKNDVPEEVIGVPIKVLDFIPKLFDDSDSEEMGALTIGLRNPKDIGPPPLGNMEAKEYAFSVEVCEQDKGKPCKKLFQQSDKNDGEKIQTIPESGDSQVPGSELGDLAMEKNPKPLQVDCTELKDVVHDQFKTQKNDVPGEVIGVTIKVLDFIPKLFDDSDSEEMGASTIGFRNPKDIGQPSLRNIEAKEYAFSAEVTKEDKGKAQSSDIIHDVAEHINSLSSIEDCLALLLIDQPLEWTCGNCSKVNRTNNGEQMMANTNVNTAVGGDQTEQSDRKTCPSEQSSELNSLSVGYSSPSRQPHGGCDAQGQLILSGDSTTEDTSGTSCGEKDSASKKPESPEGVQEAVPKCLPTEKQTNQLSAQDSQDTSTQNQGCGTQVKLEEDQTEQKDGNCGATQTILLTNLPPVLTIQLKRFVGDISKLRGHVSFKEILNVGPFVHPSCVDKDNASYRLVGVVEHLGPLLNGGHYIAYVRAGCNQQSSGSSSWVCANDHTITEVSLQEVLRCEAYILFYERMDG
The following text describes a protein:
Function:
Heterochronic protein which controls the choice of stage specific cell fates. Regulates the timing of the second larval stage events (L2 events) in the hypodermis (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSTVVSEGRNGGNERYSPQDELPDLENLKLTDDMRVPSFDRLPSPTPRYYGSCKWFNVSKGYGFVIDDITREDLFVHQSNLNMQGFRSLDEGERVSYYIQERSNGKGREAYAVSGEVEGQGLKGSRIHPLGRKKAVSLRCFRCGKFATHKAKSCPNVKTDAKVCYTCGSEEHVSSICPERRRKHRPEQVAAEEAEAARLAAETAASSPRGDHDD
The following text describes a protein:
Function:
Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes; Regulates also the sphingolipid metabolism.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MASNRCVTCAIPVKYLFTEYGQDNFVLEICPNCKRFTDPYIEQSSIILILDLFLLKPQVYYHLLFNSKHSFQSFNSQLPPSTPTLSHLASDQPRSSNQVDHQNRKACKRVHLQLSGLIYCLILVLESSFQALDEAQSVELFLDSNPVKQIMMKLLGLLFHIFNLVFTATIISRVVSYGGSYQGLDPIKQGILNSIQGIIISLSPGIVLYSTIMIFQNSYGTRPPPPLFSPTENVYSSHVLHFLRAHLGYDVSGMLDGLVGIDMDQLGSTKLKRLLIRNLMGSLSCSVGIAASFAQSWTFGFLVLCFCSILKRLLAHLLHQLDLLSPS
The following text describes a protein:
Function:
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
Subcellular Localization:
Membrane.
Sequence:
MCPICLLLLLLSLFIPVFGKVPRPQNVRMDSVNFNNILRWDPPTTNGSEAYTYAAEYKLDLQRATNYTKICQTNETQCDFSVITYDSIVRMRAELNSSISEWVTIPFDPYSQTVISAPEVRVASRAGYLDVSFFGPMRESDGMSLKDLYGDFKYKLFYWRQSEPSLVTSMDSIQNFETLADLDKWTNYCIRVQAYAPDFNKTGELSKAICEKTTHDGLIPGWKIALTFIIPLFISAVIIVGMFYLGSTIYKVAKYLCFPKYSFPEHLKEYLSQPFYNPPHLPTQGPDDVGETYGTLTLVSEENQEV
The following text describes a protein:
Function:
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. Increases tolerance to penicillin possibly by inhibiting the formation of the CidAB holin-like complexes within the membrane, thus reducing penicillin-induced lethality. Possibly plays a role in programmed cell death (PCD), triggering PCD in response to penicillin, and possibly other antibiotics, and environmental stresses.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
The following text describes a protein:
Function:
Can catalyze the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose and trehalose.
Sequence:
MKISDGNWLIQPGLNLIHPLQVFEVEQQDNEMVVYAAPRDVRERTWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAEFKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGETVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYMTNRGYGVLVNHPQCVSFEVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTSFTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRRLKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNPDACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWNVLKDTVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFWSHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTQLKCRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEAGDVQFYLPEGRWTHLWHNDELDGSRWHKQQHGFLSLPVYVRDNTLLALGNNDQRPDYVWHEGTAFHLFNLQDGHEAVCEVPAADGSVIFTLKAARTGNTITVTGAGEAKNWTLCLRNVVKVNGLQDGSQAESEQGLVVKPQGNALTITL
The following text describes a protein:
Function:
Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MEMGMDNLHSTGVYIVKYLQENFIKSQDWFVFVSFAADLKNTFLILFPIWFHLSESVGVKLVWVAVIGDWLNLVFKWILFGQRPYWWVHETTFFVNSSAPTILQFPVTCETGPGSPSGHAMGSSAVYYVMAHAVISALLENKTTFRSRFERCALWLFFWSVQVNVCLSRVFVAAHFPHQVIAGVFSGMLVAEIFNHVQCIYKTSFKRYIYATLFLFFFALGFFLLLKVFGVDLLWTLEKAKRWCARPEWIHIDTTPFAGLLRNLGVFFGLGLALNTQMYRDSCRRKKGAQFTFRLCCIMISLLVLHLFDSLELPADNEILFYFLSFCRSVTVSLAVVAVVPYCISHALQWQKKKFT
The following text describes a protein:
Function:
Histone methyltransferase that specifically di- and trimethylates 'Lys-20' of histone H4 (H4K20me2/me3). H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression (By similarity). Contributes to dosage compensation of X chromosome-relative to autosome-linked gene expression, possibly by converting H4K20me1 to H4K20m2/me3 on autosomes. Involved in the regulation of growth and body fat metabolism downstream of the TOR complex 2 pathway.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MQLHEQIANISVTFNDIPRSDHSMTPTELCYFDDFATTLVVDSVLNFTTHKMSKKRRYLYQDEYRTARTVMKTFREQRDWTNAIYGLLTLRSVSHFLSKLPPNKLFEFRDHIVRFLNMFILDSGYTIQECKRYSQEGHQGAKLVSTGVWSRGDKIERLSGVVCLLSSEDEDSILAQEGSDFSVMYSTRKRCSTLWLGPGAYINHDCRPTCEFVSHGSTAHIRVLRDMVPGDEITCFYGSEFFGPNNIDCECCTCEKNMNGAFSYLRGNENAEPIISEKKTKYELRSRS
The following text describes a protein:
Function:
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
Sequence:
MLNTPRICVVVIGKTLEEFLSQLEAAQTAVDFVELRIDYLEQINPNWVRIIKNHTHKKAILCCRARADGGKFLGTPEAQQEILQAGNDLGFDYLDIDLPVANKISIHEKKAKIIISYHNFLHTPPITELNFLLENMRLFNPDVFKFATKSEQYEDVKTLFKLLINKKNNENMIVLGMGEQGKIIRLLSPLLGGYLTFSSINGAISAPGQIDFKTMQDFYQRFYKISSPLKGED
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MARLCAKLRVLFFVSNVLYLVPCRYCRKENKFKVNPYLSLLAFGINISLASVHLCFDWLQIWNGERRDASRIFNFLQMLHTLTLPVTIVYMHLIAFTKRVRITALFNALFTDRSWRFFGDRSNSWYESSRWLGRFATAITIGTMLYLSLLILSQYNSSTKFPLYVTILEAVRVYVTMIAILIYIVCVLVVKMHFRQLQDRVEQFGASVYTARQWCLIVDRYGAAVNLVNEINHIFSELLLVMLVQVQVQLCCQYFILFCSTVDGLVPIVTGLTVLHTQLWESLFLLMLLVVGYACDSCHNQIQDVNVAVRNNVGSLNTQRVEARKWVDRFLLQKLSQTNQQRFMAGGLFVLDNKLVCTALTSMITYLVILIQFRKYDFEDYVVTFRNDSNISF
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Sequence:
MALEGGKKKKYTVIAIATMLVVAAVVGTIFHVRRSTKEIEIHTEEKTGAVILLAATVVTATTIIILCKYTDFRDICRETLERIKAGIKAPSQLIKASFAHAVERIQFAIDKSSTIRQSEKDPRAVVALDQCKELLGVSIDDLKRSINKVSLFDVPKLKDNTIELRVWLSGSVTYQETCIDAFDNTTSNSGPAMVKLLDLGIKLTRNSLAMLDGIIELAGGKPPISKIFVPRVPQEPEPTTTVIDIDNNQPELPQPEVPQTKPKGFIFDWRINRKGPQPEVPQPNPKTINVDIDQNIPQPNPKTINVDIDQNIPQPNPKTINVDIDQNIPQPKSKTKTINVDVQGNVPQPKPKTKTINVDIQGNVPQPKPKTKTINVDIQGNVPQPKPKTKTINVDIQGNVPQPKPRTTVWKKEVTIVHSHGTKPVEVTGRRMLDQTPIDDQEPESQSENEPIMLHETDTPYPTWADTSRRSLINADPGTLKPNAVVAQDGSGQFKTIMEAVNTAPKRSPQPFIILIKAGVYKEYVTIPRGIDNVVFLGEGPTKTKITGNKNYIDGVATFHSATVAVNGDGFMARGVGFENTAGPDKHQAVALRVSADMSIFHNCVMEGYQDTLYTHSYRQFYRQCSISGTIDFIFGNAAAVFQDCKMIVRKPMSNQACMVTAQGRKDQHSVGGLVFDGCTITAEPDFLSAAPMPKSYLGRPWKEFSRTIIMQSFIDKNIDPEGWAPWVGTFGQDTCYYAEFNNKGPGADTSRRVKWKGVKKISQQEAASFGPGTYIQGDTWIKASSVPYDAGLMRI