lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subcellular Localization:
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein.
Sequence:
MLRQTLTQASRMRPCISVVGFRGFHASSPCEATLKEIEQRLKSIKNIEKITKTIKTVAQTKLTRAQRAMEASNKYYRVSDEVFKEAGTKAPEEGKTLMVACSSDKGLCGGIHSSISRLIRRELHDPKTFENTSLCILGEKVRTQLLRFCPESFYLTFAHIGGASPSFEEALQISSNILEHAKDYDRIVLVYNKFASAVSFETVMKNLYTTKAINESPNLSAYEVSDEVHQPLMEFAFANAIFSAMAEAHCSEMSSRRNAMENASKSAGDMINKFSIQYNRQRQASITNELIDIVTGANSLA
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MEHAGVAERLHGKTVLITGATGFIAKLLVEKILRLQPRVKRLYLLVRARDQDSATERVRSEIMQLQIFLSLREKYQNHFTSWFWDKIFPVAGDVSLNNLGIGNVHLAEDIVKETNIIIHMAAAVNFRERYDTALAINTMGMKHLLDVALRCVKLELVLLVSTAYVNSKKSGVVLEKPLQQYRSYDGQSELDISEEIAFAEAKLEELVCSSASEDAIRHTMKKIGTERARKFGWMNTYVFTKAMAEMLAYEHRSRLPIFIIRPTSTTSTLMEPFPGWIEGIKTIDVWVTNYGMGHLKFLPGDVTTIMDIVPADIVVNAMLCIISCHPQGPLDLIYHIGSSMRNPLKIGDLLHAMFRYFLEKPFVGAEGEVIKVKQLVVPATMDSFYEHMDIHYKMPLEDMVRRGLSTTGEQDRYNHLKREYNFTVAVAEVFQAGTFFKRRFDDSNMQRLITFLNERDRELIPCDSKFINWKKYLMEIHFPSVMECESREATRARL
The following text describes a protein:
Function:
High-affinity potassium transporter that does not show potassium-sodium cotransport. Potassium transport seems to be independent of sodium. Mediates transport of the divalent cations magnesium and calcium in the absence of competing potassium ions. Selectivity for potassium is dominant over divalent cations, and magnesium and calcium transport may be small and may depend on competing potassium concentrations.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Localizes to the plasma membrane.
Domain:
HKT transporters are proposed to contain 4 pore-forming regions enclosed by transmembrane segments with each containing a potassium channel-like selectivity filter motif.
Sequence:
MPIRLHIFVSSARHAINSSALICRFIAFHLSPLLIHLSYFLIIDVLGFVALVVLRPSNHKYNPRYIDMFFLSTSAVTVTGLATTQMEDLSSSQIAVLTLLMFLGSEMFLSFLGLVLESSKQNKHDPENRRVSSVTVCEQSHLEEAIPQTPSMNSTDIKRSCHKYLVFVVLAYMIIILVTGSLLVFMYIAHVSSARDVLTRKSINKALFSISVTVSSFTNGGLLPTNESMAVFSSNNGLLLLLIGQILAGSTLLPMFLRLVIWALRGLRLAKAEEPDFMMNNSSSVGFSHLLPNLQTIFLAAVEVAFVGMTVILFCCLNWDSAVFAGLTSLQKITNALFMAVSARQAGENSIDCSLVAPAALVLFMVMMYTPSLTKLFSACQDHKQIGPESDDRTSKGKPFLKTMAFSPLAFNTTVIMLVCITERRSISTDPLNFSTFNIIFEVISAYGNIGLSTGYSCSRQLQHQDGIACHEKPYSFSGWWSEPGKLILVLAMLYGRLNSKDSTSARTR
The following text describes a protein:
Function:
Accepts electrons from ETF and reduces ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MITRQTTRRALRSLPGLSRVRLQIITGIQRGDEVINKSHHTNGTATLQGSRWFASSATLRKTAELPFSELSEEEQLLVGSEREVDKVDVCIVGGGPAGLATAIKLKQLDNKDGSGELRVVVLDKGSECGSHIVSGVILEPRAWRELFPDDCDEGIPIPSELVTKVEREEFRFLMGNLALPIPEPPVMVNKGNNYIASLSQVTRWLAEKAEEVGVEVYPGIAVSDVVYSSDGSSVVGVATKDMGLSKSGRPKGNFERGMEFHARQTVFAEGCHGSLTKQLVKKFALRENRDNQTYGLGIKEVWEVMPEKFNKGFVSHTMGYPLSNDLYGGGFQYHFGEGLVTVGLVVGLDYKNPWVSPYQEFQRMKHHPYYANVLEGGKCVAYGARALNEGGLQSVPKLHFPGGCLVGATAGFMNVPKIKGTHTAMKTGMLAAEEIFKALAPLPSLSELEEMDGASLVETPINLESYEAAFRKSWVYDELWQVRNIRPSFGSKLGGYGGMAYSAVDSYILKGRGPWTFHHHKSDAAVTGPASEYRKIEYPSPDGKISFDILTSVSRTGTYHDEDELCHLRVPDQDPKLHTAKAYPKWKGIESRFCPAGVYEYVEDSSSPEGVKFQINSQNCIHCKTCDIKVPTQDIDWVVPEGSDGPKYTLT
The following text describes a protein:
Function:
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.
Subcellular Localization:
Nucleus.
Sequence:
MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALKQYYLRYLEKYEKVHHFGEDDDEVPPGNPKPQLPIGAIPSSYNYQQHSVSDYLRQSYGLSMDFNSPNDYNKLVLSLLSGLPNEVDFAINVCTLLSNESKHVMQLEKDPKIITLLLANAGVFDDTLGSFSSVFGEEWREKTDRDFVKFWKDIVDDNEVRDLISDRNKAHEDTPGEWIWESLFHPPRKLGINDIEGQRVLQIAVILRNLSFEESNVKLLAANRTCLRFLLLSAHSHFISLRQLGLDTLGNIAAELLLDPVDFRTTHLMFHTVTKCLMSRDRFLKMRGMEILGNLCKAEDNGVLICEYVDQDSYREIICHLTLPDVLLVTSTLEVLYMLTEMGDVACTKIAKVEKSIDVLVCLVSMDAQMFGPDALAAVKLIEHPSSSHQVLSEIRPQAIEQVQTQTHIASGPASRAVVAQHAAPPPGIVEIDSEKFACQWLNAHFEVNPDCSVSRAEMYSEYLSTCSKLARGGILTSTGFYKCLRTVFPNHTVKRVEDSTSSGQAHIHVIGVKRRALPLPIQMYYQQQPISTPVVRVDAVADLSPTPSPAGIPHGPQAAGNHFQRTPVTNQSSNLTATQMSFPVQGIHTVAQTVSRIPPNPSVHTHQQQNSPVTVIQNKAPIPCEVVKATVIQNSVPQTAVPVSISVGGAPAQNSVGQNHSAGPQPVTVVNSQTLLHHPSVMPQPSPLHTVVPGQVPSGTPVTVIQQTVPQSRMFGRVQSIPACTSTVSQGQQLITTSPQPMHTSSQQTAAGSQPQDTVIIAPPQYVTTSASNIVSATSVQNFQVATGQVVTIAGVPSPQPSRVGFQNIAPKPLPSQQVSPSVVQQPIQQPQQPAQQSVVIVSQPAQQGQAYAPAIHQIVLANPAALPAGQTVQLTGQPNITPSSSPSPVPPTNNQVPTAMSSSSTLQSQGPPPTVSQMLSVKRQQQQQHSPAAPAQQVQVQVQQPQQVQVQVQPQQPSAGVGQPAPNESSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQVANNQAAGFGVQGQTPAQQLLVGQQNVQLVQSAMPPAGGVQTVPISNLQILPGPLISNSPATIFQGTSGNQVTITVVPNTSFATATVSQGNAAQLIAPAGLSMSGAQASAGLQVQTLPAGQSACTTAPLPFKGDKIICQKEEEAKEATGLHVHERKIEVMENPSCRRGTTNTSNGDTSESELQVGSLLNGRKYSDSSLPPSNSGKLQSETSQCSLISNGPSLELGENGAPGKQNSEPVDMQDVKGDLKKALVNGICDFDKGDGSHLSKNIPNHKTSNHVGNGEISPVEPQGTSGATQQDTAKGDQLERVSNGPVLTLGGSPSTSSMQEAPSVATPPLSGTDLPNGPLASSLNSDVPQQRPSVVVSPHSTAPVIQGHQVIAVPHSGPRVTPSALSSDARSTNGTAECKTVKRPAEDNDRDTVPGIPNKVGVRIVTISDPNNAGCSATMVAVPAGADPSTVAKVAIESAAQQKQQHPPTYMQSVAPQNTPMPPSPAVQVQGQPSSSQPSPVSASSQHADPVRKPGQNFMCLWQSCKKWFQTPSQVFYHAATEHGGKDVYPGQCLWEGCEPFQRQRFSFITHLQDKHCSKDALLAGLKQDEPGQVANQKSSTKQPTVGGTGSAPRAQKAIASHPSAALMALRRGSRNLVFRDFTDEKEGPITKHIRLTAALILKNIGKYSECGRRLLKRHENNLSVLAISNMEASSTLAKCLYELNFTVQSKEQEKDSEML
The following text describes a protein:
Function:
Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones.
Sequence:
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPQYEGHAAPPDEILKSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKDQETIDNEMDHFKPTETLKELSEALDTIKEQVDEVLDPILVIQAENDNMIDPQSANYIYDHVDSDDKNIKWYSESGHVITIDKEKEQVFEDIYQFLESLDWSE
The following text describes a protein:
Function:
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNLEPGECGMNSVSCGNGKLRQWLIDQIDSGKYPGLVWENDEKSIFRIPWKHAGKQDYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDPYKVYRIVPEGAKKGAKQNSMEEQPLMNHPFPITSPYTSLPSQVPNYMVPHERNWREFAPEQPHPDIPYQCASVPFAARGHHWQGPGCENGCQVTGTFYACAPPESQTPGIPIEPSIRSGEALALSDCRLHICLYYREMLVKEVTTSSPEGCRISQGQSYEVSSLEQVIFPYPEDNSQRKNIEKLLSHLERGVILWMAPDGLYAKRLCQSRIYWDGPLALCSDRPNKLERDQTCKLFDTQQFLAELQAFAHHGRPLPRYQVALCFGEEFPDPQRQRKLITAHVEPMFARQLYYFAQQNSGHLLRGYDLPELMTSPEDYHRSIRHSSIQE
The following text describes a protein:
Function:
Extracellular signal that regulates meristem maintenance. Acts with CLV1 as a ligand-receptor pair in a signal transduction pathway coordinating growth between adjacent meristematic regions and controlling the balance between meristem cell proliferation and differentiation; [MCLV3]: The secreted peptide MCLV3 activates a signal transduction cascade to restrict WUSCHEL (WUS) expression, inducing shoot and root meristem consumption as cells differentiated into other organs.
Miscellaneous:
MISCELLANEOUS: His-81 seems to be essential for the activity of MCLV3; MISCELLANEOUS: [Isoform 2]: May be due to intron retention; MISCELLANEOUS: [Isoform 3]: May be due to introns retention.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MDSKSFLLLLLLFCFLFLHDASDLTQAHAHVQGLSNRKMMMMKMESEWVGANGEAEKAKTKGLGLHEELRTVPSGPDPLHHHVNPPRQPRNNFQLP
The following text describes a protein:
Function:
Required for occlusion-derived virus (ODV) envelopment and subsequent embedding of virions into polyhedra.
Subcellular Localization:
Host cytoplasm. Host nucleus. Virion. Note=Within virion, localizes primarily to the nucleocapsid fraction.
Sequence:
MSGGGNLLTLERDHFKYLFLTSYFDLKDNEHVPSEPMAFIRNYLNCTFDLLDDAVLMNYFNYLQSMQLKHLVGSTSTNIFKFVKPQFRFVCDRTTVDILEFDTRMYIKPGTPVYATNLFTSNPRKMMAFLYAEFGKVFKNKIFVNINNYGCVLAGSAGFLFDDAYVDWNGVRMCAAPRLDNNMHPFRLYLLGEDMAKHFVDNNILPPHPSNAKTRKINNSMFMLKNFYKGLPLFKSKYTVVNSTKIVTRKPNDIFNEIDKELNGNCPFIKFIQRDYIFDAQFPPDLLDLLNEYMTKSSIMKIITKFVIEENPAMSGEMSREIILDRYSVDNYRKLYIKMEITNQFPVMYDHESSYIFVSKDFLQLKGTMNAFYAPKQRILSILAVNRLFGATETIDFHPNLLVYRQSSPPVRLTGDVYVVDKNEKVFLVKHVFSNTVPAYLLIRGDYESSSDLKSLRDLNPWVQNTLLKLLIPDSVQ
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.
Subcellular Localization:
Nucleus.
Sequence:
MDNNNNNNYQGDLADIVRASGGTTETTTTKVTTTNIGGQIPKWSFGSSNNDQYHQLKDDVYSLIPTAETLLRDMDDAIAISTSSSNTFLNNFSIDHSSATTNNNSNNNNNNNNNNNNNNNNNNNNNNNNNGVCDIFPPNMVQISQDSNKANNIEDVKLPIQSAAGALPKNVNGAASFGFMSNQMLSNFNASCSNSPKTGGFIDGANAIGGPHLQISSPRNQGIKRRKIQAKKVVCIPAPAAANSRQTGEVVPSDLWAWRKYGQKPIKGSPYPRGYYRCSSSKGCPARKQVERSRTDPNMLVITYTSDHNHPWPTQRNALAGSTRSSQPVSKTSSKPSNNNFHNVLIKEENQNNVSTTTTTTTLPVVKEEEIRLKNDGFESYRPLILAADPTTINNNEHEQQADQDFFTDLVEFESDDPLELFSTQGCKGFESFTGLFDWATTTNQEENDHTTIPKCSKADI
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).
Sequence:
MADIYPWQQALWSQLGGRAQHAHAYLLYGPAGIGKRALAEHWAAQLLCQRPAAAGACGECKACQLLAAGTHPDYFVLEPEEAEKPIRVDQVRDLVGFVVQTAQLGGRKVVLLEPAEAMNVNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCVQQACPLPGAAASLEWLARALPDEPAEALEELLALSGGSPLTAQRLHGQGVREQRAQVVEGVKKLLKQQIAASPLAESWNSVPLPLLFDWFCDWTLGILRYQLTHDEEGLGLADMRKVIQYLGDKSGQAKVLAMQDWLLQQRQKVLNKANLNRVLLLEALLVQWASLPGPG
The following text describes a protein:
Function:
Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.
Subcellular Localization:
Secreted.
Sequence:
MRLSTATLLLLLASCLSPGHGILEAHYTNLKCRCSGVISTVVGLNIIDRIQVTPPGNGCPKTEVVIWTKMKKVICVNPRAKWLQRLLRHVQSKSLSSTPQAPVSKRRAA
The following text describes a protein:
Function:
Core component of the H1 type VI (H1-T6SS) secretion system that plays a role in the release of toxins targeting both eukaryotic and prokaryotic species. Forms a dodecameric ring-shaped structure located at one end of the T6SS sheath. May properly attach the pre-assembled sheath onto the baseplate and/or stabilize the sheaths tubular structure.
Sequence:
MLDVPVLLAAVSPDSPCGDDLEYDAAFLELERIAQGQPERQMGDAVLPAEPPEWPRVRALASELFGRSKDLRVANLLLQSNVALDGLDGLADGLLLVRELLGQYWDGVYPLLDADDDNDPTFRINALTGLVAEPLLQLVWAIPLVRSRAFGPVNLRAALNAAGLQRFASETLSPEQIAGAFADADADALAATRRALDGAQEHALAIESGVAERVGSAQGLDLGPLRQLLRQALQVFDLYGPQGAGESLAPGAEAVADEQVGAAPVAAVAAPAPRASGEIANREDVLRQLDRLLEYYVRHEPSSPVPVLLKRAKTLVTADFAEIVRNLIPDGISQFETLRGPESE
The following text describes a protein:
Function:
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
Miscellaneous:
MISCELLANEOUS: Present with 358 molecules/cell in log phase SD medium.
Subcellular Localization:
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSSSAIKIRNALLKATDPKLRSDNWQYILDVCDLVKEDPEDNGQEVMSLIEKRLEQQDANVILRTLSLTVSLAENCGSRLRQEISSKNFTSLLYALIESHSVHITLKKAVTDVVKQLSDSFKDDPSLRAMGDLYDKIKRKAPYLVQPNVPEKHNMSTQADNSDDEELQKALKMSLFEYEKQKKLQEQEKESAEVLPQQQQQHQQQNQAPAHKIPAQTVVRRVRALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYVTPIVEPSKEEIEKEKNKEAIVFSQKTTIDQLHNSLNAASKTGNSNEVLQDPHIGDMYGSVTPLRPQVTRMLGKYAKEKEDMLSLRQVLANAERSYNQLMDRAANAHISPPVPGPALYAGMTHANNTPVMPPQRQSYQSNEYSPYPSNLPIQHPTNSANNTPQYGYDLGYSVVSQPPPGYEQ
The following text describes a protein:
Function:
Cleaves the arabidiol side chain at C15 to form 14-apo-arabidiol and a side-chain fragment. Involved in the biosynthesis of the volatile homoterpene (E)-4,8-dimethyl-1,3,7-nonatriene (DMNT) in roots. Involved in the production of DMNT by degrading the triterpene arabidiol. May be involved in the defense again the fungal root pathogen Pythium irregulare by producing DMNT.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MDAIVVDSQNCFIIILLCSFSLISYFVFFKKPKVNFDLLPSPPSLPIIGHLHLLLSTLIHKSLQKLSSKYGPLLHLRIFNIPFILVSSDSLAYEIFRDHDVNVSSRGVGAIDESLAFGSSGFIQAPYGDYWKFMKKLIATKLLGPQPLVRSQDFRSEELERFYKRLFDKAMKKESVMIHKEASRFVNNSLYKMCTGRSFSVENNEVERIMELTADLGALSQKFFVSKMFRKLLEKLGISLFKTEIMVVSRRFSELVERILIEYEEKMDGHQGTQFMDALLAAYRDENTEYKITRSHIKSLLTEFFIGAADASSIAIQWAMADIINNREILEKLREEIDSVVGKTRLVQETDLPNLPYLQAVVKEGLRLHPPTPLVVREFQEGCEIGGFFVPKNTTLIVNSYAMMRDPDSWQDPDEFKPERFLASLSREEDKKEKILNFLPFGSGRRMCPGSNLGYIFVGTAIGMMVQCFDWEINGDKINMEEATGGFLITMAHPLTCTPIPLPRTQNSLISHL
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MAEGVGNTPGQQTVDFSLLVKRTAEDAFSSLRELAGIAQEQSDSERKLSLLKNFLRTRQRLLRVLSLSKWCRQIPLVERCQQLSGTVSNHDTSFTQAADFLFFLHEGLQQARAPIYDIPTAAEVLLTGQYNRLPKCIEELGMQPMLAGEEREEALQKLDTMLRSRLLDISLPKEISDITVSEGRIILQVDGEFKVQLTAGYRGHLHLWRILHLELLVGESTGPTKFTDHQRLALGDDLERRMAASDDPFRILFSILHEFCTTLVMDTLFRQTGMLRQGRWKDAIRFEKISEASNISQGVGIGQGTGQGPGPPGDSDPERVGAKSRGSPGLRIWYWLDCPKGISGVDPNSPPHLRIEPGPDQHIVCSHQPSVIDPTTESEAEFSIDQSCIDVERLLLRAIACNIHTRLLEVQRGLKGSNQLWRVDCDVVLRSSFSEDGEVKSSPSPDENNSSGSSGEAGEEVLCVRAYGDSFMALGISIRNGRFLIRSPSTLLANSVLAEMEDALNQGSKDPVDIFLNLRSRSLLHVFASLGTNFNLKIYERGALALKFPSDGPKLGPDVLVLGFPNCGEVYFLSLHLDSNFMPFFMLLEAQPRTLSGRSTFSSGPINIIRCMKVNIETMLVTEDDASFSLLDEGRLELERQTISAVNVSKKGTGKELMEFVGKKTEVSVLDSRGFGRSLTGGTVLESVQTELTGEKFYRGSPAAHLSRTNNPLSPSFSPIQSPSGLQGMAASNPQYAGSNIINQGPNAGFSPGNSSLAASSLLQSNHRVGRIGNGIMASPARSPLHRGVTSLKSPYQGEQDVLQSKSPLHAGESAASPIDLDYDDISKLIDSISSKTPGVPPGASHTSPAGEPVPLASRQPRVGLTRSLPMVKSPAMNPRTPQTKSSSLQGLSSGRVSGQTATVLARLSSPRKPLGSQAGELAAEWMDLDQSSQAVQSPSMLLSPSTRPATGVQGHSYNRGPQSSEKLPSDFFKRKRSGPELLFSLPSIQAVATSGEKVKRRKTEQEGSQSLVGQLADVTSFRTLPVLDSFVGQPYSTIVVAANQGKAPMGSYTAVLLQVVRRCWLCIKHARLTRQMDALNIPYVEEVGLRKPSSNLRFRLPSREANRDSKKYDSAGWQQICLCLGKPGSDGWEVEVQDAHFKALWELQLQKPSSWGSGVQFATLPEEDSHISCTQKGLVLRYSAVEDDSVKKLVADLERLWSARMFAVGIRKLLEEKVEERAEGAQEKGEGEQDKGPRIHGRGRFSIGERSEGGEKKWEVMRRAFRVEAVGLTSTWFTYVGSLPGVMARFVVEWEAGNRGCTVHVSPEQLWPHTKYLEDYINGGEVELLLDSIRVSVGPLQALAAAIRPARMLGPATSAVIPSGSVQGVINSGLASKPTGGGLLLGQVSSPIPSSTTTASAIAQARLPNGSTSVLNMGNTGTNMQGSQAAGLASGPGRPIIPGLVPSSLLPTDVSVLLRTPFWIRIVYRRQFAMDMRCFAGDQVWLQPAPPPRSGGTSAGGSLPCPQFRPFVMEHVAIGLQTGETVSGAGPPGNLSGNGVSQTGFGPGMSAGWGGGMNATAPSLRGNSSSMIGPRMVNNAIVMAPRGGTLQGGPSNSSVMAVNTGRVLNNGPSAGLRSEYTAIFGLGDDGGYGGAWVPLAALKKVLRGILRYLGVLWLFAQFPTILREVLGEILKENEGALLNHDPEQPALRFYIGNCVFAVSMHRQQLYLQAINVKKFQQQQNAHAQGQSGGPDNELSDPEMAEIGDFFARRVASEPYDASRLASFVTMLTLPIPTLREFLKLIAWEKELQKASANQSQGGDGTQTSRPKIELCLENRVGSAFSPVQEEAGAQGTSSTAKSSIRHIRAQNIVEFTLTLYLDGHQLPPINVAGGAGWLPQCVAVRLSYQFSEPSRLSVVNVEGSHGGRACWVRQEDWEHSKVVITNAVDHYVPGNDQGLGRLQPVAELVQRTVQQAVLSLRKGGLNAPSPMASPYAS
The following text describes a protein:
Function:
Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis. Phosphorylates and restricts the asymmetry effector mex-5 (and possibly also mex-6) to the anterior cytoplasm of the zygote. Regulates mes-1 expression during early embryogenesis. Critical role in postembryonic vulval morphogenesis. Involved in the establishment of neuronal polarity.
Subcellular Localization:
Cytoplasm, cell cortex. Note=Colocalizes with germ granules (P granules).
Sequence:
MSSASVGKKPEHVNTPPGDNQQKSSKENQKSNKDKQSSNQPPGQIPHSTNSGTRKSSGSGLKTANLKHPARPSTESSTSSSHHRRPAQEMNGTSTATATGGGGTSGATTTASSGAPAASSGGSSARYSSSGRSHPTSGSSSSHARSTGQSGMSSRSAARRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWMNVGYEDDELKPFIEPPKDQIDEQRIEKLIQIFQLGFNKAAILESVEKEKFEDIHATYLLLGERKSDMDASEITMAQSLLSHSSINVSSSLGQHPAGVITREHVTSSSASGSSASPSRYSRSSATATGASITAGSALASAANAQKHQQSSAAPSSGSSSSRRSSQNDAAATAAGGTVVMSGTRHGGVQMRAQPTSRQATISLLQPPSYKPSSNTTQIAQIPPLFNRNSTATSSAAQPSTGITGTRKIADPKGRIPLNSTAVQGHRTATGAVAANNGGIPSHRDHAQQQQYMNQLTSSTMMSKLINKTPAAGGTAATSSSSSSSATSTAPLQKSGSQISHAPTEPVIREDDDENNSENQNGNVPLIGGVGPQTSPAVQVPTEDATSSSDKEQQQQKASSETPKESKPSMIHQSPSMPPSQMMTAMESLKLSESGQTGGPTVATGGPPQRATSQQMSRSATTNSANMGASSGGAAAAASATNQLSGAPSSTGASSQQYHPKAPSSSSSSSTNPPHQHQLTHNASFSVTPSSYQIPTSTAVNVTSTGMPTSSSSSAFPRNTRNRQTFHGKTEKDKGGDDSSDEIGETPGNVSIGATGPSANNAEATIWSKLSKLTRRDHNRESMTQPVSGRAGTIGASQGQQTAAALAAIREQSGPIAPGAGQVAPSLPIHEGDVKPRSLRFTWSMKTTSSLAPDDMMREIRKVLDANGCDYEQRERYMILCVHGDPNTDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIGFKNIASKIAQELNL
The following text describes a protein:
Function:
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
Subcellular Localization:
Cytoplasm.
Sequence:
MTQKLHIKTWGCQMNEYDSSKMADLLLSTHGLELTEAPEEADVLLLNTCSIREKAQEKVFHQLGRWKELKKNNPNLVIGVGGCVASQEGEHIRHRAPYVDIIFGPQTLHRLPEMINQIRGGKSSVVDVSFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTFCVVPYTRGEEVSRPVDDVLFEIAQLAEQGVREVNLLGQNVNAYRGPTHDGQICSFAELLRLVASIDGIDRLRFTTSHPIEFTDDIIDVYRDTPELVSFLHLPVQAGSDRVLTMMKRAHTALEYKSIIRKLRAVRPDIQISSDFIVGFPGETAEDFEQTMNLIAQVNFDMSFSFVYSARPGTPAADMPDDVTEDEKKQRLYVLQERINQQAAQFSRRMLGTEQRVLVEGPSKKDIMELTGRTETNRIVNFQGSPEMIGKFVDVKITDVYTNSLRGEVVRTEDEMGLRIAQSPQEVMNRTRKEDELGVGRYHG
The following text describes a protein:
Function:
Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 20a in the D-loop of several cytoplasmic tRNAs (acp3U(20a)).
Domain:
Contains 1 DXTW motif.
Sequence:
MEDDAWLDLVGISADPPNRRNKCEKCKRPVVVCWCPALPHPPEAVSSQIVILQHPAEEKRSLRTALMLQLGLEPGKCVVYKGKRFPNHRNHADLQRILDSPQTLLLYPSRDSVPLEEVDHSAGPYTLVLIDGTWPQAKAIYASSPALHRLRQVKLIAVGISDYIIRTQPTEGCLSTLETAAQCLAVLESRPELRQTLVRPLHTLCKYQLDNGAVEHQSKEFLLKNNQYPKPIGKRLSRLLRNTACDGNEET
The following text describes a protein:
Function:
Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. Seems to be involved in the phosphorylation of RPH1.
Miscellaneous:
MISCELLANEOUS: Present with 6900 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Domain:
FHA domains are phosphothreonine recognition modules, FHA 1 strongly selects for Asp at position +3 relative to phosphothreonine, whereas FHA 2 selects for Ile in this position.
Sequence:
MENITQPTQQSTQATQRFLIEKFSQEQIGENIVCRVICTTGQIPIRDLSADISQVLKEKRSIKKVWTFGRNPACDYHLGNISRLSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSNQLLSQGDEITVGVGVESDILSLVIFINDKFKQCLEQNKVDRIRSNLKNTSKIASPGLTSSTASSMVANKTGIFKDFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKMSPLGSQSYGDFSQISLSQSLSQQKLLENMDDAQYEFVKAQRKLQMEQQLQEQDQEDQDGKIQGFKIPAHAPIRYTQPKSIEAETREQKLLHSNNTENVKSSKKKGNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKLTQMMAAQRANQPSASSSSMSAKKPPVSDTNNNGNNSVLNDLVESPINANTGNILKRIHSVSLSQSQIDPSKKVKRAKLDQTSKGPENLQFS
The following text describes a protein:
Function:
Multifunctional enzyme that catalyzes the carboxylation of acetyl-CoA, forming malonyl-CoA, which is used in the plastid for fatty acid synthesis and in the cytosol in various biosynthetic pathways including fatty acid elongation.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MAESDQISELCKALGGDSPIRSVLVANNGMAAVKFMRSIRAWASETFGTDKAILLVAMATPEDLRANAEHVRIADQFLEVPGGTNNNNYANVQLIVEIAERTRVSAVWPGWGHASEDPELPDALKEKGIIFLGPPSAAMAALGDKIGSSLIAQAAGVPTLPWSGSHVKVPQETCHAIPEEIYKKACVSTTEEAVASCQVVGYPAMIKASWGGGGKGIRKVHNDDEVRALFKQVQGEVPGSPIFVMKVASQSRHLEVQLLCDKHGNVAALHSRDCSVQRRHQKIIEEGPITVAPPEKVRELEQAARRLAKCVQYQGAATVEYLYSMETGEYYFLELNPRLQVEHPVTEWIAGINLPAAQVAVGMGIPLYNIPEIRRFYGMEHGGGYHSWKDISAVAAKFDLDKAQSVRPMGHCVAVRVTSEDPDDGFKPTGGRVEELNFKSKPNVWAYFSVKSGGAIHEFSDSQFGHVFAFGESRSLAIANMVLGLKEIQIRGEIRTNVDYTVDLLNATEYRENKIHTGWLDSRIAMRVRAERPPWYLSVVAGALYEASSRSSSVVTDYVSYLSKGQIPPRHISLVNLTVALNIDGIKYTVKTVRGGPGSYRLRINESEIEAEMHSLRDGGLLMQLDGNSHVIYAETEGAGTRLLINGRTCLLQKEHDPSKLLADTPCKLLRFLVRDGSHVVADTPYAEVEVMKMCMPLLLPASGIIQFVMPEGQAMQVSDLIARLDLDDPSSVRRAEPFHGTFPKLGPSTAISGKVHQKFAASVNSAHMILAGYEHNINHVVQGLLNCLDSPELPFLRWQELMSVLATRLPKDLRNELDGMYKEYELKADFQKGKDFPAKLIREAIEANLAYCSEKDRITNERLIEPLMSLVKSYEGGRESHACVVVKSLFEEYLSVEELFSGGIQSDVIERLRLQHAKDLEKVVHIVFSHQGVKNKNELILELMDGLVYPNPSAYRGQLVRFSALNHTAYSGLALKASQLLEQTKLSELRTRISRSLSELEMFTEEGEWVSTPRRNMAINERMEDLVCAPVAVEDALVALFDHSDPTLQRRVVETYIRRLYQHCLVKGSVQMQWHRSGLIALWEFSEENIEQRNGQSVTLLKQQVENPMGKRWGVMIVIKSLQFLSTAIEVALKETSHYRAGAGSVSDGNPINSNRGNILHIALVGINNQMSTLQDSGDEDQAQERINKLSKILEDKTTTSHLNGAGFRVVSCIIQRDEGRPPMRHSFQWSFDKLYYEEDPMLRHVEPPLSTFLELDKVNLEGYSDAKYTPSRDRQWHIYTLEKNNKDPRSNDQRMFLRTIVRQPSVTNGFSFGNIDNEVCRAQASSSFISNSILRSLMAALEEIELHAHNEAVRSGHSHMYMCILGEQRLFDLIPVSRRTGEIGQDEETACTLLKHMATNIHEHVGVRMHRLSVCQWEVKLWLDCDGQANGAWRVVVTIVTGHSCTVDIYREVEDSNTHELFYRSATPTAGPLHGIPLHKPYKPLDALDRKRNAARKNETTYCYDFPLAFEKALKESWKSGISHVAQANGHNQGYAQVTELMFADSTGSWGTPLIPVVRPPGMNDIGTVAWNMNLSTPEFPDGREIIVVANDVTFKAGSFGPREDAFFDAVTNLACERKIPLIYLAATSGARLGVADEIKACFHVGWSDDESPERGFHYIYLMEQDYSRLRSSVIAHELKLESGETRWVVDTIVGKEDGLGCENLHGSGAIASAYSKAYREIFTLTFVTGKAVGIGAYLARIGMRCIQRLDQPIILTGFSPLNKLLGREVYSSQLQLGGPKIMAANGVAHLTVSDDLEGVSAILKWLSYVPAYVGGPLPILTPLDPLERPVTYFPENSCDARAAICGVQDDTQGGKWLGGMFDRESFVETLGGWAKTVITGRAKLGGIPVGVIAVETETMMQVTPADPGQLDSAERLVSQAGQVWFPDSAAKTAQALLDFNHEELPLFILANWRGFSGGQRDLFEGILQAGSMIVENLRTYKQPAFVYIPKAGELRGGAWVVVDSKVNPEHIEMYAESSAKGNVLEPKALIEIKFKPNEIEESMLRLDPQLARLNARLLKEIKVGTSEAEAVRIRSTMAARRKQLMPIYTQVATRFAELHDTTSRMVAKSVLSKVVDWEESRAFFYRRLRRRVAEDSLAKQVREAAGEQMMPTHGSALERIKEWYVASQGQGDGEKWNDDEAFFAWKDDSSNYDKHLEELKAERVSRLLSQLAESSDVKALPNGLSLLLGKMNPSKREQVINGLRQLLG