lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
DNA ligase involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair.
Subcellular Localization:
Nucleus.
Sequence:
MNDCENFSPSPEFKWLCDELLGKIYETSSKKHLIGKPVTVRYLEIITNFIKLWRSTVGNYIYPALRLIVPFRDRRIYNVKENTLIKALCRYLRLPKSSETENRLLRWKQRAARGVKLSDFCVEEIRKRQKDYEGANRITIDELNGYLDEVSQEGNGKRMGYMALTDSRAFNYCLNHMTFMEMKFFFDIILKTRVLSGLENMFLTAWHPDATDYLSVVSDLDVLSQRLYNPNERLRQTDLSITISHAFEPQLAKRTHLSYERVASKLQHDFIIEEKMDGERLQIHYINYGEQIKYLSRRGVDFSYLYGENSSSGPISPSLKLHFNVKDCILDGEMITYDTEKDIVLPFGLVKSSAMNQIQSELAGIAPTESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMKAINAEAIKDSLEQAISMGSEGIVLKHLHSKYFVGSRNTDWIKIKPEYLEQFGENMDLLIIGREQGKKDSFFCGLSISDPNEVAEKPRFISFCTIANGLSNEEFKDIERKTWGKWHIFSEDPPSPNLLGFGTKVPYEWIHPEDSVVLEVKARAIDTKESEKRKYRSGCTLHFGYCKQIRYDKDWKTVASFSEFEDMKDARNFYNKRKSHQVTDGKKRASKRAKIGIVNSSEPTALVAPVSNTFSNCRFRVISDYFDSTKRRRISQEDLCSVILEHGGEIVYTSDENNLPQDNLYIIGEKLTRECKILLNAKNLIIRPSWIFSCIEEGYKTPFTESDIFRGELESSMDCSQFYTDFNTASLNHLLETANRGIKNPDSDLLLPEVPLFLFSNLKLAVLNSENVLDTSILEVEFAIKCHGGELVHIENASIIIVFNDFISREDLFSLRQKIASKAVKESTESTPRIPRMVDISWALDSIKDNYIAETEHYQCL
The following text describes a protein:
Function:
Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos.
Subcellular Localization:
Apical cell membrane. Cell projection, cilium. Cell junction, adherens junction. Note=grdn-1-dependent localization at sensory neuron dendritic tips. The coiled-coil domain is sufficient to localize to apical junctions.
Domain:
The coiled-coil domain is sufficient to localize to apical junctions.
Sequence:
MSTTTPEKPEEIIDATGTSDTAEKIEVVISKEEPAEQKNEVEEPDYAQVPAESEDDAAQELAPTDSAIQVVHVLEAPQKAELVTIPLAHSEAEDHKLADADRDQEEELVFNEERRKTVTMDDNASLRSASITFDANRDEQDLLNESFASNPTDETVLMQKTKDEMDATSERPRSPLDLPPPPASVVLHPSAPPPPPPPLSSTEVVGNTTTTTTTHYAPKTWNDPSITTAPKIPVSLLSGAQPLPSVLTQRTTTSSYSAPNYSASSMSGVPSDVAPPPPLPIPNQSSSSAASYQHHHASSISKSISSSREDLLSEHATSRSTVREIPVHRAPSTAPSHSSVFEYHMMPTTTSTYHHVETPSDEYYRREVMTRTIITRSTEALSQTPLGRPASPLDRYLPYPTTTTTTSGDGRTREEKTVDYKVTYHRDIEEQERRIREDQARRQQEEQDRRDREDNARRILAQREHQEMERLREQQNLSERALAERERADKERLQQERLLRQQREKKRREEWDRLESIRLAEEEAELARRRALEKERIDREKAEEERKTMERLERERARLERERLEEERRQKEKAETERIERERREHERIEIERIERIKRERIERERREREEKKAEEDRLLRERLELERIERERRELEARERQELELQRREAEDRERQRLEDEAREMRRREEERREAELVADVHRQAEERERLRKRQEREEAERLERIRLEQQKIDMERIDAERRERERKEEERREFELIEAARRKKEARDRDRLDEMERERVREEEERREKERREQERRIAAEKERKRRQEEEEEIARLNELQRAAAARQAQRNAELDRQRQRDELDRKAQELSEREMREKERRDRERANEEAQLADLLERERHNQLIRENERREAVERANNRRLEDRRSRDKLDHIVRERSEKEQFELEKRRLLAEKEAMNRKKNHLLSSETLAKLTQPMYYTTREPEVTTKVERQVIERIDRNVWVEDVPYAPSQSAMGYLDNDENNRDRLYNPNDLNRNGSSRSRYQRAKNEKARRDFYHSSQDSADPVTERFRKSTDDLTTRSRPEYRGPLLQKFHDSEFRTTALNETDGLPYRRMGPSPYEQPFAKLLEETERRYAHYNSRASNPSIYQSSRYYYPERHGQPQHTDNTRAESVVAYERESRRESPADQAHIRSRSADYLMDRRIREETEVPENQLQKTRVEPHDQSPRESRISEYEMRFRKSTEKLTVPDWYRENRPQGQTAQTSTYRYGNGVEPMSTTTTTTTVINGTSSHQQAPPPVPPQPIGNIGLPRGMFDRYKDDIEELRRSRSSLHQTGQQETSNRQGSTLSVGGIVDQGHALPGYTVSEVPNAWNLHTSRTSRVVEVADTFVGTSSHEYGNFTNRYGGRVTIEEVLDSIFQKVTPTNQRLNFDRSYPQADELFQGNVDGPGIYTNNYSVMRQVLKSPERAEHILQNEELFVRCTECHRTRELSAARLFFVSCKHCYTYYCSRECRHNNWPNHSGRCSFARINTLCKDVIMKVREDEQAQAFMSKVARDGFSVSGRGSVNIRLSSPQLAQAYVSNGWRALSAYPNDQLLYYYTVKALIAERKEPSLIALCNRYEPREKFILSVSIIADIEHCPETPPPETRELSAVQFSSPRSRYEAIQNQNAPYFSEFAHNV
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
Sequence:
MASIINKQIISPTGRNMEIINYEILKKYPLCDRCFGRLYAKLLHTTNTERGRALKLYKALELEAKIKKAKEKGINYEEELELLKALAKSGVDEIRLEDIEIEKENCPWCRGIFNKQKMEKLLNKAIELLKEYDFDTFLIGTHIPEEIKDLEKEIETEFMESIKQEFGREFGKMLAVRLDKAPDKEYPDIVVHINPYTEEIYLQINPLFIKGRYRKLVRGIPQTRWPCRKCRGKGCELCNYTGKKYPISVEEIIAKPFLEATKGVDAKFHGAGREDIDVRMLGDGRPFVLEIKEPKIRKIDLNKIAEEINKDGRVEVLNLEFGVRKDKVIFKNTPHRKTYRALVECSDKITDEELKLLEKELENRTIYQKTPKRVLHRRADLERIRKVYKVKTSKVDDNHFEMIIYCDGGLYIKELISGDDGRTNPSVSSILNKNCICKELDVLKIHDNNLLEKG
The following text describes a protein:
Function:
Protein transport. Probably involved in vesicular traffic from ER to Golgi.
Sequence:
MSQKKADFDFLVKLLIIGDSGVGKTCLLMRYCENLFTNNHLTTIGIDFKLKTIEVGGKKVKIQIWDTAGQERFRTITQTYYKGAQGIILVYGVDDRVSFQSIENWMKQINTHAQEGVSKLLVANKSDCADRVVQTQEGQRLADQYGIPFFETSAKNGTNIYEIFNSIAKMVIDKQNKDPLDRPSNVQLSQQPQSEVQKKQGGCC
The following text describes a protein:
Function:
Involved in pre-mRNA splicing as component of the activated spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MNPLTKVKLINELNEREVQLGVAEKVSWHSEYKHSAWIFVGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTVLAVDNFNGIKIKGRTIRVDHVSNYRAPQESEDVDDVTRELQEKGCGVKTPPSSPPEVSEDEDAKLTKKHKKDKKEKKKRKKEKTEGQAQAEQPSCSRSATVKEKKDERASRKHSSKTSERAQKSEHRESKKSHSGSPDGRSSYHARAEDPECKARKEKPKHEHKSASRREAEEKSRERERGRSSGTHSGRHRGHSDGRSHRSRSRSRSPDKSHRHKKYRHSRERDSYHGSDRRHH
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
Subcellular Localization:
Nucleus.
Sequence:
CAAIACRSADIVGLASLVSMEMNELVALDVGTVKGLILMLVIRKRKLSVAACDALLDLSTTLIGRQRLLKFSALERLVPASSILVSLYNEDGSSIACARIAFKEDGHSIPSKLSEKFLDSMKSLWEKVHNQMLLGNAWMSFQERDLNLSNVTVNNLAESIFSFSINTSEFVIPLPSVTEHPSKKEVHFFQKKFDPSCFRKHAFNAMDIMKCEEAFKEGYTIALSFGLQVLQLLQMLTSIYLTPPNSQGWDRHCDDHCVFLPRLYDPLDREQCFVEENSLAGYRKFLLREGDILYIPRGFPHEAYFPYVTFGIEVEPPFEWEGFAHVALHCWYQTQKQLHRASVEPLSGILDLMPVTLLHVMIELIGASDSTLREASLKTTFNNIIDQINKASRFLEVFSSVEVAIETNKETETIQEHDWNLAFYEFQNLFPSCAQVKSKFCDEVLFEDVIDSYKLLLEKYKKAIYEWNARATL
The following text describes a protein:
Function:
Thought to regulate endocytosis in coelomocytes through modulation of phospholipase C activity. Possible acetylcholine receptor.
Subcellular Localization:
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Sequence:
MIFPLMILVLFNTIPIRVSEADEESERHQAYLDHRKLKEDVLGPLDGSMPSELPVFIGAQLKLDHISRVDEKTGFLTLALTVKFMWSDERLQWDPSHYSGFTRTRLEFVDFWLYQIWKPRIYMTNTYERRQSKTIDLLSNTLVEMDIHSKGFVMTTTKILLKTFCFLDFKGYPHDFQNCSFSFIPNMNANDIFLGSSMLKAKFTKDFTDPQQVVRVQDFQINDVVTEDLYLFMNRIVLHDLTREPRSLVRSFVSFTIVLQRKNVYVHLQLYAPMIFICTCLIISGFLPSEYALPLLVFNLISEYLYFHNIKDVLPTDFDGTPTIALIATFTLAETMSIIGWKMFIITIMTKKQKAYFLNSSKFPLDSGFFNIRVLRRLLTIDKFLMYMLIAQSFGSIFIMLKD
The following text describes a protein:
Function:
Component of the ASTRA complex probably involved in chromatin remodeling.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MVVPTPFYVLRGHSSSVTSVLFDANEYLYSGDEAGFVICWCLTSMRPKCAWRAHTKTILGMQIVKGGALCTHGRDCRLVTWKIDFNCMTDNFMSLSKLAELQNYGPEASSETEKSSAFISIHSNIVVNSLTFCPFSYSPQSKIVVLCNTLNFEELDVYDDESLYHPQTHKEDCGKRLQTRIQPEESVGKTGSVMSTSVTVTDEKYVLLAAGYESGHVVQYICSLENVKTVTLDFKAVWKMVYAYKSHSQPVLSVEYAGSKLFSTGADDCICLHPTPSSIADDLGSLPHPIFRKTKHCGQQNIRIRSDNKILATAGWDGRGRVYSCQTLAPLAVLKYHSDGINSLAFHPGSNVIALASKDTRISLWKLY
The following text describes a protein:
Function:
Has antibacterial activity.
Subcellular Localization:
Cytoplasmic vesicle lumen.
Sequence:
MRLLVTLILLIFVLTVSGQYSCSNPCYGNMCCSIPSNNEYYLTTFCDESTACGTPCSAQTYFTADSQRFGCGVTLTICSTSGGSTTTGGTGSAGTSTSSGSGSGSGSGSGSGSGSGSGTSGSSSSGSSSGSGSGSSSGSGGSSGSGSGSTMETGGFYGVCVKAITIDAGPNISVEEEAGMAIIDASSQICQDLFGSSSCGWSDKRSITAVQSSVEDGFPVNKPFNVTFEDYNKIISNSLILDQQCSNKNNCKYNKLELMK
The following text describes a protein:
Function:
Plays a role in ascaroside pheromones biosynthesis, which regulates development and behavior. Specifically, activates the side chain of medium-chain indol-3-carbonyl (IC)-ascarosides for shortening through beta-oxidation. Converts IC-asc-C7 and IC-asc-C9 into IC-asc-C7-CoA and IC-asc-C9-CoA, respectively. May play a role in fatty-acid metabolism by activating and converting nonanoate (C9) into nonanoyl-CoA (C9-CoA).
Subcellular Localization:
Peroxisome.
Sequence:
MIFHGEQLENHDKPVHEVLLERFKVHQEKDPDNVAFVTAENEDDSLGFQQLGKKVLQISEWFVENGYKKGDVFLLASYNNWRCFAAALGAWRAGLIVSAAASQFTSFEMNYQIEDSQSQVILVDKHTLPVVQEACKNLKFVKQIISISANPPSPVIKFDVLTSRLVRNLKMPLIDPKNDIVFLPYSSGTTGKPKGVMISHLNFSMMLESSLRFFDANAKAIGLPPDFVLPYDLHFLPMYHAMGMFRTLLTSYRGTTQIMFTKFDMELMLKNIEKYSIMVLSLVPAIAVRMLNSPLLQKYDVSSLVSVTVGSAPFPESASKKLKQLLPNVNIVQGYGMTELTFATHLQSPGSPDGSVGRLVPGTSMKVKKEDGTLCGPHEIGELWIKGPQMMKGYWKKEQQTNELLDEHGFMRTGDIVYFDKNGETFICDRIKELIKVNAKQVAPAELESVILEHDDVADVCVFGVDDASSGERPVACVVSKRGRDMETSKAIMKHINQKLARYKHIKEIEFVSEIMRTGTGKLLRRAMKKAFLDAKKAKL
The following text describes a protein:
Function:
Participates in DNA repair and in chromosomal DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MDVEQVKKKLHTALKFGGFNIRREFCGKIVAKFLREGIDLENKHHFDNCVKNLCSSLENQCLLGHSIEKEHIDRALEVCLKSGYDRNETIFSVINAFDFPKVSYNLDRKQYYLTENKPRLLSSADSKAQLFADRYATILHRTKRNFIQKATENTNIKLELQTVDYLLTLSNVSLNHTLVLGSLLQVSEGKYYLEDPTGIVQLDLSHAVYYGGLFAENCFVLVNGHYEDKIIKVSTLILPPGEEYANSRPFFNTINYFGGPSPTPLKDSVKLRDHLQRNRGASFMFFSNVWLDHPSIFEKLELLFEGFNPSPPAAFVFMGNFMSESCSSNKMDTLRKLFKQLAELINKYENLATVTNFIFVPGLEDPCTSYVVPRLPIPSCITEDMTKMVKKAVFTSNPCRLQYCNKEITIFRADVLPKLLQASLHKPKKSELSENLTRTIISQGHLSPLPLNALTVHWDFDYTLSLNPLPDLVVIGDKAEPYEGKYKGCQLINPGSFCESGFQFKAYNPATDKIEECLL
The following text describes a protein:
Function:
Acyl-CoA-dependent lysophosphatidic acid acyltransferase with preference for oleoyl-CoA. Involved in triacylglyceride homeostasis and lipid droplet formation. Involved in vacuolar protein sorting (By similarity).
Subcellular Localization:
Lipid droplet. Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Note=Lipid droplets consist of a surface phospholipid monolayer and a hydrophobic interior. The latter makes embedding of proteins containing transmembrane segments difficult, and these may instead adopt a hairpin or monotonic conformation when associated with lipid droplet membranes (By similarity).
Sequence:
MEKFTRWRDPGTGIAPFHPINTETPSGFNFKWILIVVVMILRVPLCIISVTLWFLWSCFLKPILSIQPKLSFFIDSSLSRLLLLCFGCLKLSKSTSGSFVQGDSLQPGDILAVNHSSPLDVLVLSCLYNCTFAVCDSKTSNVSIISAQAYFWSCFFSPSKLKITDAKPLAKVAAKASKIGTVVILFPEGVCTNGRALCQFTPCFDSAKETDRIFPLYIKYLPPCVTLPVPSLLSFARSVLLTVSFEIRIRFSAEPLIPRNCTDVTESAQEVLSKLGRSRVVKLGKSDKLSYLDARSKKHV
The following text describes a protein:
Function:
Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs (e.g. leaves) and coordinating socket cell recruitment and differentiation at trichome sites. Regulates the positional cue and cell proliferation along the body axis.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MAPEENGTCEPCKTFGQKCSHVVKKQRAKFYILRRCIAMLVCWHDQNHDRKDS
The following text describes a protein:
Function:
Involved in the chaperone-assisted selective autophagy (CASA), a crucial process for protein quality control, particularly in mechanical strained cells and tissues such as muscle. Displays temperature-dependent chaperone activity.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MADGPGPFSCHYPGRLRRDPFRESPLSSRLLDDDFGLTPFPGDLTAAWPDWARPRLTSAWPGPLRSSLGRGPPLAPPGYGGRYEGPAEGRSPPAWPGEPWKVCVNVHSFKPEELAVKTKDGFVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYYQFGDGGFGGELPVGGQETTCA
The following text describes a protein:
Function:
A-kinase anchoring protein for GSK3B and PKA that regulates or facilitates their kinase activity towards their targets. The ternary complex enhances Wnt-induced signaling by facilitating the GSK3B- and PKA-induced phosphorylation of beta-catenin leading to beta-catenin degradation and stabilization respectively. Upon cAMP activation, the ternary complex contributes to neuroprotection against oxidative stress-induced apoptosis by facilitating the PKA-induced phosphorylation of DML1 and PKA-induced inactivation of GSK3B. During neurite outgrowth promotes neuron proliferation; while increases beta-catenin-induced transcriptional activity through GSK3B kinase activity inhibition, reduces N-cadherin level to promote cell cycle progression (By similarity). May play a role in cleft palate formation and is required for postnatal life through modulation of the activity of GSK3B during development (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
METDCNPMELSGVSGFEEEAELNGFEGTDMKDMRLEAEAVVNDVLFAVNTMFVSKTLRCADDVAYINVETRERNRYCLELTEAGLRVVGYAFDQVDDHLQTPYHETVYSLLDTLSPAYREAFGNALLQRLEALKREGQS
The following text describes a protein:
Function:
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Sequence:
MDRGMCVSLWCEEVEDDAAQDQGQGEDQAQGCTGGSPQLRAAWDPTVSGHRVIQRLLHLEERYMPSMLYTTLIQRDPERREELAKWALEVCCDCGCDEAVFPRSVSLMDRFLSASLSLAVSPYCLAAGCVLIASKLTECDGVTADSLCAAAEYSFQPSDLREMERVILSTLRWDTAAVTPQDFLPHFLASVGEQGDAEREMLSTLRRHSDTLAAMCACDSRFLGAPPSLVAAASLNCALRGLSNKGPTQLSKSSEALAELCQTDLVVLQCYSEMIESALRQRLRGGLQQPPMEKDEEMENERPGTPTDMREINF
The following text describes a protein:
Function:
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.
Subcellular Localization:
Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Sequence:
MTDLAVVICPLMAFLLYYNTLQAGFVYDDKRAILDNADVATESPLADLLSHDFWGTRLNASGSHGSYRPLITLSFRWTAQLVGLDRAYWHHWINVMLHCAVTSAVTLIAGRVSLFLFRRDYSYGSYVSGLLFAAHPVHCEAVAGLVGRADMVCTLFFLAGLFTYTKRNLTGTLILTLAAFLSKEYGIMLTPVCLLYDLVVFSRSRIKRTIFNWVVLTAWSIALMTFRFWLSGFHTPQFARADNPTAASPSWTTRSLTFLYLPVFHFGLLLWPRWLSFDWSMDAIQPVTSLKDIRNLATLIFYTVLAVAIRKIVSTRHPKYRIVLALAVITTTIPFLPATNLFAYVGFVIAERILYLPSVGFCLLVGLGVQMLIKQRQFHQMIFGSILILLLASGWRTIKRNGDWIDEEHLYRSGIEINPPKAHGNLGVVFQQSGRLTEAEWNFKRALSYRPNMADVHHNLGNLFQQQSRYEESLQAYNKAIHFRPQLAGKFRIAYSEKAKVLYKLKRWAEAERTLLDCTRLKDDFLRDSRAHQTAKVSATILLGDLLSKNSSREKEAENWLLQARQLAPKNPLVYYQLGEFLSARSRHNEAAEVLIQAAEMDPNNVAWTVAAAHALHDASRNVEAEVYFRRAANLFPLDISHRLNLGAVLHVQGKLDEAEQVYLKALRLSPNHPLTTVNLRRLRNSLLNMRSSQHQNHKCNQSLT
The following text describes a protein:
Function:
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
Sequence:
MKTKTNQSVKTFGIVGFPLSHSLSPLIHNSIYKDRNINASYLVFETQNLNVEKIQEFRNSGILGLSVTIPHKETAFTLADKADDTSRIMKASNTLLIGPDSTYAYNTDGEGAYHSILEFSPESLKTGKVVILGSGGSARGIAFSLAVSGKIQNLLVCSRNEITAKEICLLVTKNSNVKAEPISQDVLLTRKEEISLVIHTTPLGMKGQSPGPYLPEDFFNSNMTLFDIVYNPLETPLVKTAQKAGAKIIPGSEMLLYQAMKQFELFTGISPNAEDIIKTRERLSKALENR
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MSSRECLLAYELLQEHYGKIAADVASFLLQNGWQPLRYIALKANLKLDQVRKALCLLIQHKLAKFHVRKRKIVEYAINIENVLSILFHPKFIYTVKLLYGDAAELIVEEALQHGIILMSTAIKNVADRLPDENGSGKIEKAFKDLVQTHFLQREPEVEKNEEEEYIVPIFTQNEADLYRLPTLSEESLKRKRSDDGSDEPKAKRLKSEHETPSVKDDGVYWSVNISRFQQYFRDQSIVASVTQRFGTPCGEIVRAMLRISEVTTPANAQSTQPISSAEIARSLPQKLPMEHVEQHLKLLSNDEDQIVQLFDDSGSGGLYVVNLKNSALALATATVLSYVQQRYGSKACRIFRLLMLKKHLEQKQVEEFAMIPPKEAKGYLYHMLAENMVIMQEVPRTPDHAPARTFYLYSVNIQRLSRILLVKCYKTCTNLMTRHNHLIKTNKRILDKEERITAIKVRVNATLPDADEAQLEEIEEMMTSSERTSLTKHQHCCNKLHTAQNQLLNTIFVLDSYLNALSSA
The following text describes a protein:
Function:
Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity).
Sequence:
MDIVSVALQRYSTKAFDPSKKLTAEEADKIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYTFNERKMLDASHVVVFCAKTAMDDAWLERVVDQEDADGRFATPEAKAANDKGRRFFADMHRVSLKDDHQWMAKQVYLNVGNFLLGVAAMGLDAVPIEGFDAEVLDAEFGLKEKGYTSLVVVPVGHHSVEDFNAGLPKSRLPLETTLTEV
The following text describes a protein:
Function:
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (By similarity).
Subcellular Localization:
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex (By similarity).
Sequence:
MDSETRELRALEAEVAALQRECRMLQNAGEKASGAWKSFQKISQSDSEEWESLKDLRSQLEHLRSEHSFLSKLTGFNIRNYSKMEDIVNTEETEKDTKKVLQKHRLSGNCNMVTFQLEFEVLEMETKEKKSSIITDLSIIMEPTEYSELSEFASRAEEKRDLLMFFRSLHFFVEWCEYRENTFKHFKEKYPDTVYLLEGTCSHCMEIRSTRQPGFELVIVWKIQIDEEGMVFPKLDLLTKVPERALGLDKNRVIETAPLSFRSLLGVLGIEAALDSLIRLFSGDNN
The following text describes a protein:
Function:
Transcription factor involved in the control of neuronal differentiation in the brain. Regulates dendrite development and branching, and dendritic spine formation in cortical layers II-III. Also involved in the control of synaptogenesis. In addition, it has probably a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator; [CDP/Cux p110]: Plays a role in cell cycle progression, in particular at the G1/S transition. As cells progress into S phase, a fraction of CUX1 molecules is proteolytically processed into N-terminally truncated proteins of 110 kDa. While CUX1 only transiently binds to DNA and carries the CCAAT-displacement activity, CDP/Cux p110 makes a stable interaction with DNA and stimulates expression of genes such as POLA1.
Subcellular Localization:
Nucleus.
Sequence:
MAANVGSMFQYWKRFDLQQLQRELDATATVLANRQDESEQSRKRLIEQSREFKKNTPEDLRKQVAPLLKSFQGEIDALSKRSKEAEAAFLTVYKRLIDVPDPVPALDLGQQLEIKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKSQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKLQTLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLNAKNSTLKQLEEKLKGQADYEDVKKELTTLKSMEFAPSEGAGTQDSTKPLEVLLLEKNRSLQSENATLRISNSDLSGSARRKGRDQPESRRPGPLPASPPPQLPRNTGEQVSNTNGTHHFSPAGLSQDFFSSNLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSTIFSTGPYSTNSISSPSPLQQSPDVNGMAPSPSQSESAGSISEGEEIDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQRGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPVQASSTASSGNSDDAIRSILQQARREMEAQQAALDPALKPAPLSQPDLTILNPKLLSASPMSTVSTYPPLAISLKKTPAAPEASTSALPSAPALKKEAQDAPTLDPPGSADATPGVLRPVKNELVRGSTWKDPWWNPVQPERRNLTTSEETKADETNASGKEKTGSSQPRAERSQLQGPSATAEYWKEWPNAESPYSQSSELSLTGASRSETPQNSPLPSSPIVPMAKPAKPSVPPLTPEQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLNGELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPTIETSKEGKPPEPSDPPTSDSQPTTPLPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGIDYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQAGASDSPSARSSRAAPSSEGDSCDGVEAADTEEPGGNIVATKSQGGPAEVTAAPADREEATQPAEKAKAQPLSSGTPGQDDGEDAGRSRPPPEGLADAPAPVPNLAAPAAGEDAATSATAPAMATEAPGAARAGPAERSSALPSTSAPANAPARRPSSLQSLFGLPEAAGARDNPVRKKKAANLNSIIHRLEKAASREEPIEWEF
The following text describes a protein:
Function:
In complex with CCZ1, is required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis. The MON1-CCZ1 complex acts at the fusion of vesicles with the vacuole, through its regulation of the SNARE complex during the coordinated priming and docking stages of fusion, and particularly at the stage of tethering/docking.
Subcellular Localization:
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Sequence:
MEPTSEHSSIKEEVENDNVHRSHESECGSLLLNPGNVLMAAPSVSEDDQEVSRSTPELRSHVENVEQLLSDILHDNSSPLNVSTSVSSSSNNTAVDEIIKLLSLISFDLAKQKRTYLIFSSSGKPVFSNIVDDSIEPSTVGALQAIISSFEVSKEELTSFSTFSNVIVVLSKNPLYLVGVSPSTTLSAAYLLSELNLLYCQILTGVTAKAMQLTLNSRPNFDLRRLIGSNEQFLKELCDQLNDYELVPTLNAISPLPLRSSFRDQLSQLLLRETPKSLLFTFIAIRGRLVCMVKAKKLLLHANDLYLLFLSLFRTQSFNDSMEHWVPVCFPTLNPDAYIYIYSYFLCKDTVLIMGSSESGVFFEMQSVKCKVAQEIQDHGWLKKLIYCEEMDRTTPRNPGSPCISHYLFYSKKYSQFYTPGYSFSTPNFNTRTLYAIYASLHDQAFHKKNSFSINMTVHESLLLFTWSTASFDFHCIANATTSSQLLIANVNKILRWIRREENRLFIQTNLSF
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MKRIKKNPDSDSGNRSDPDGQNAIMRETERKCGGFNLNLMRVMGILVAILMVISVVFSVSVVLKDPPSDTALESSQAANVFQVKQEKGSEGFSRPAGDPYDKLLGGLLAAGFSERTCLSRYQSAFYRKELPHKPSSYLISKLRSYEILHKRCGPHTEFYKKALEQLKFGNQQASSDCSYVVWISYSGLGNRILTLASAFLYALLTNRVLLVDPGIDIIDLFCKPFPEVSWFLPTDFPLRDQFNSYNQMSPSCYGRMLKDSSSTNLHALKPPSHAFLQKIPWLIMKTDNYFIPSLFLIPSFEQELNSLFTNKETVFHFLGRYLFHPTNSVWGLITRYYHAYLAKADEKIGIQIRIFDSGTGPFQYVLDQILSCTTKEKILPEINRQDPSTSQSGDCKSKAVVVTSLSPWYSEKMRNMYWEHPSMTSESVGIYQPSYEEYQQTEKQIHNRKAWAEMYLLSLTDVLVTSSWSTFGYVAQGLGGLKSWILYKPENQSAPDPPCVGAMSMEPCFHAPPFYDCKAWRGIDTGALVPHVTHCEDMSWGLKLVDVKNWV
The following text describes a protein:
Function:
Positive regulator of FPS1 glycerol channel required for the glycerol efflux. As a component of the RNA polymerase II holoenzyme, is required for SSN8 destruction in response to oxidative stress but not heat shock. Required for cell survival in response to heat shock independent of SSN8.
Subcellular Localization:
Cytoplasm. Note=Displays diffuse cytoplasmic localization, but very rapidly aggregates into punctate spots that appear near the cell surface in response to hypo-osmotic shock.
Sequence:
MSDYFSSRPSQTLTPMGNKPSGGGGGDDASSIHSKSSQYLMDILPDSMTLNESVSSIVANNQAKEFILPETDERSPYFINVPIPKAQPTSTTETKKPLAGDEAIDGQFVKEYPTDILVDRFYKWKKILKGLVIYLREVAYAQEQFARINYQLKGSVKFPFLTDIDETTNTITDPFTTAPRGPKKAQPAQKKVGLTDSEQFQMQMQQEQQENAVQAPTDESKMSLAPHEYKPVQTTESDNTSAASGFVKFGSGSIQDIQVILKKYHLSLANQQFKISKEITSTVIPKLEELRKDLRYKITEIKDLHGDFKTNIGAHIQLTSQLLKKYIAAVKFMNAHGIGNDRASPTNKKPHKLDPKHDPYLLKLQLDLQLKRQVAEETYLQEAFINLQSSGLQLEKIIYTKIQHALLRYSALIDSEARLMIKNMCQELQHGIISKPPAFEWDNFVTQHPSCLLNWKSNDPIPPPRKVSDVIYPHMKSPLAKCIKAGYFLKKSELLPTYHQGYFVLTSNYIHEFQSSDFYNLSSSTPNSTKSSAYSSSVSIADTYANANNAKANNHHRQASDVHNSSTTTGGTAGANGIRGIRKKSYLAPIMSIPLNDCTLKDASSTKFVLVGKPTLNENADVRKSSSSTYLSGSSQASLPKYGHETAKIFSKAPFHKFLKGSKPKNKNTKSSELDQFYAAAQKESNNYVTWTFKIVSPEPSEEELKHFKRWVQDLKNLTSFNDTKDRIKFIEDRVMKSHRFKAGHMSRNSVNIGSHTPCLTDSTFTLQDGTTTSVNLKGRAEKPQYIHIQNNSLADFDGNGFRSKVNTPAIDDYGNLITVERRPAQSPHQYSDYMATSGNTTPSYSSGSRPQSMYNGYNPAVSITSNGMMLQQSTANNNTNPTTNLRHQRNISQTSSLPGFSYTSLSLPVNSPGSSNSESSSGGYFAIPLHGNNNNNNYTQRNSEGSSPCYNDDQIRQQQQPLQMQPLSRTSSSSVNVTAMRSTSAGNSITANAPVVPKVMVNNQNVKTVAADQSATAPSSPTMNSSVTTINRESPYQTLKKTNSTGNVPCLTAEKTHAHPAFYKRGNNSAQNLTTSSSTASRVHPIRKHKKNVSFSSLNSLMFSKKGANHGGNLMTNQFMSGGIQEDDGDSTNNDTIKLNQSIYS
The following text describes a protein:
Function:
Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Subcellular Localization:
Secreted.
Sequence:
MAQSLALSLLILVLAFGIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIPAILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSKGCKRTERSQTPKGP
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MASSANALRLGLRTCSRPTQTSNLRIAALQRRALSATATRCEGVPVPKREDDAKLEFTRPYNPGEFLSEKLRSDDLQDWERERYERALTSWEQTPDDLKRGWSTMIRDIEQAAAPLRRVVMPRRSTFWYEEEKDTDLITNEDGEDDFHENDIMSLGHGKLEEHREFREYARIAVWEMPLLSKYAKPFVPPTSEEVLRFRYTTYMGEFHPADRKVVVEFCPKDLRDLSEVQQRKLMKLAGPRYNPEKDIIKMSCEKFEHQAQNKRYLGDLIEKMIAAAKDPKDTFEDIPLDTRHHTFTKKISFPKEWLLTEERKKELEAARQQALLKDAEKVVQGALVDGADVVKQYLESGAAEALHAVPVMAGRGGKALPGGKGGKMQRSKR