lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MQTVYLKEHEGNAHNFVGTLSSAASAPWWSAFGSQSVHQGESCGQVKPFSLELPNCIDQLAATKPLARGADQVLGKGHITQFTIFPDDCKMSDDAQKLQTTMSLQSSLTDPQSRFEIGFSLPTICAKYPYTDQFYGLFSAYAPQISGRIMLPLNMTSDDEPIYVNAKQYHGIIRRRQSRAKAVLDHKLTKRRKPYMHESRHLHAMRRPRGCGGRFLNTKNSVDGNGKIGNEVHKTVGEQLQSSGSQSSEFLQSEVGTFNSSKETNGSSPNISGSEVTSMYSRGGLDSFSLNHLGSAVHSFADMIDGGRGMIIPTKWVAAAGNCCNLKV
The following text describes a protein:
Function:
May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MGTPFVWALGLLMLQMLLFVAGEQGTQDIADASERGLHMQKLGSGSVQAALAELVALPCLFTLQPQPSAARDAPRIKWTKVRTASGQRQDLPILVAKDNVVKVAKSWQGRVSLPSYPRRRANATLLLGPLRASDSGLYRCQVVRGIEDEQDLVPLEVTGVVFHYRSARDRYALTFAEAQEACRLSSAIIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYPITQSRPGCYGDRSSLPGVRSYGRRNPQELYDVYCFARELGGEVFYVGPARRLTLAGARAQCRRQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRFANRTGFPSPAERFDAYCFRAHHPTSQHGDLETPSSGDEGEILSAEGPPVRELEPTLEEEEVVTPDFQEPLVSSGEEEPLILEEKQESQQTLSPTPGDPMLASWPTGEVWLSTVAPSPSDMGAGTAASSHTEVAPTDPMPRRRGRFKGLNGRYFQQQEPEPGLQGGMEASAQPPTSEAAGNQMEPPLAMAVTEMLGSGQSRSPWADLTNEVDMPGAGSAGGKSSPEPWLWPPTMVPPSISGHSRAPVLELEKAEGPSARPATPDLFWSPLEATVSAPSPAPWEAFPVATSPDLPMMAMLRGPKEWMLPHPTPISTEANRVEAHGEATTTPPPSPAAETKVYSLPLSLTPTGQGGEAMPTTPESPGADFRETGETSPAQVNKAEHSSSSPWPSVNRNVAVGFVPTETATEPTGLRGISGSESGVLDTAESPTSGLQATVDEVQDPWPSVYSKGLGASSPSAPLGSPGVFLVPKVTPSLEPWVATDEGPTVNPMDSTVTLAPSDASGIWEPGSQVFEEAESTTLSPQVALDTSIVTPLTTLEQGDKVGVPAMSTLGSSSSQPHPEPEDQVETQGTSGASVPPHQSSPLGKPAVPPGTPTAASVGESASVSSGEPTVPWDPSSTLLPVTLGIEDFELEVLAGSPGVESFWEEVASGEEPALPGTPMKAGAEEVHSDPCENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAERDCRRRSGHLTSVHSSEEHSFINSFGHENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQHHVATIRCRSNGKWDRPQIVCTKPRRSHRMRRHHHHHQHHHQHHHHKSRKERRKHKKHPTEDWEKDEGNFC
The following text describes a protein:
Function:
Cytoprotective ribonuclease (RNase) required for resistance to abiotic stresses, acting as a positive regulator of mRNA decapping during stress.
Subcellular Localization:
Cytoplasm.
Sequence:
MASTGWLKGRVKAVPSGDSLVIMGNSKAEIPPEKSITLGSLMAPRLARRGGVDEPFAWQSRDFLRKLCIGKEVTFKVEYTVPSIGREYGTVFLGDKNVSMLVVSAGWAKVREQGQQKDANPYLKPLQDAEEQAKQQGLGRWSRAPGASEASIRNLPPSAIGDASNFDAMGLLEQSKGKLIEAFVEQVRDGSTLRVYLLPDFQFIQVFVAGIQAPTMGRRATSESIINTSITSDEPNGESTTEPRATPTSAQRLASSAASVTEVAPDPYGREAKHFTETRVLNRDVRIVLEGVDKYSNLIGSVYYPDGESAKDLGLELIENGYAKYVDWSANMLEVEAKKKLKSAELEAKKTRLRIWTNYVAPATNSKAIHDQNFTGKVVEIVSGDCLVIADDSLPFGDPSAEQRVNLSSIRAPKMGNPRRDEKPAPYAREAKEFLRNRLIGKQVHVSMEYSRKVSMADGPAAPASGADSRVMDFGTVFLASKDGDGAAPPPSAAGNQLPGMNVAELLVARGFATVVRHRDFEERSNYYDALLSAESRATSGKKGIHSPKEPPVMHVTDLLTAASKKARDFLPFLQRNRRMSAVVEYVLSGHRFKLFIPKETCSIAFSISGVRCPGRDEPYSEEAIALMRRKIMQRDVEIEVETVDRTGTFIGTIWESRSNVAVTLLEAGLARLQTSFGTDRIAEMWENYVEGEEVPSGGAAERHQKEEVKVTVTEILGGGKFYVQLVSDQKVAAIQKQLASLNLQEAPVIGAFNPKKGDIVLAQFSADNSWNRAMIVNAPRGAVESSKDKFEVFYVDYGNQEVVPYSQLRPLDASVSSSPGLAQLCSLAHVKVPGLEDDYGQEAAYRLSELLLSGPKEFRAVIEEKDTSGGKVKGQGTGTIFLVTLVDPESDVSVNATLLQEGLARMDKRKRWEPKDKQQALDELEKYQKEARDKRRAMWEYGDVESDDEDSAIPARKAAGKR
The following text describes a protein:
Function:
A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Acts as an omega and omega-1 hydroxylase for arachidonic acid and possibly for other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. May down-regulate the biological activities of N-arachidonoyl-serotonin, an endocannabinoid that has anti-nociceptive effects through inhibition of fatty acid amide hydrolase FAAH, TRPV1 receptor and T-type calcium channels. Catalyzes C-2 oxidation of the indole ring of N-arachidonoyl-serotonin forming a less active product 2-oxo-N-arachidonoyl-serotonin.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MDVSAGLLLEYVFSPANIAGLIAFVLVFYVLQEYQWHQTYANIPPGPKPWPIVGNFGGFLVPPFILKRFVKNSKEFAKVVSNPLSPQAGLIEMSKLYGNIFSIFVGPQLMVVLTGYDAVRDAMLNHTETFSDRPHIPLVTIITKRKGIVFAPYGPLWRTNRRFCHSTLRSFGFGRMSLEPCIHEGLAIIKTELQSLIETAGPSGIDLTPLISNAVSNIISLMSLGQRFHHEDKEFRNMRDLMSHGLEISVNTSILLVNVFPWLYYLPFGVFKELRRAELDITAFLKRIIARHRATLDPENPRDFIDMYLVEMLAKQKEGSSEENLFSEDDLFYIIGDLFIAGTDTTTNSMLWSILYMSLYPDVQEKVQKEIDAVVGSERVPSLTDKSSLPYTEATIMEVIRMTVVVPLSIPHMASETTEFRGFTIPKGTVIIPNLWSVHRDPTVWENPDDFNPSRFLDDQGKILRKDCFIPFGLGRRVCMGEQLAKMELFLMFTSLMQTFTFRFPEGATAPSMHGRFGLTLAPCPFTVCVKTR
The following text describes a protein:
Function:
Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MAFGAWRHYPATGAVAHSQQLENVASYCPIACGNRTLTKKLDGVKNMITCFDFTSRAPNLEPSAELEVSADDSVTCLANLATKDGLIVFAGNGSSVDDRVKGQDTHFKAFELQVPKGKPASINFLSKTQLFSVPKNENARKEMYQRILKLSPPPRTAASTPTKRIGTIASGLGGDENEIVIFSATSNRPQAQDIIKRIKLSAGQEANDLDIWDQGEGRFQIAYCLDSDVYIQDVDYDFSKSKNRTESERRKVYTIPHPDAGARKGRSKVRSLRWLSPKHLVLLANKPNRTGVELLVLHMYEEGPGSIVSRKTLPAHVKAAVDFDVALLDADANGAYQIVVGVGGIDVSLSVYTIDYHGSAQDSLSHLYKYATYDEISAGSNKARHVIQTARTRQLYAGATYLVIAMVVAAVALMIQSLIDPEGSLTRGMIPAKFQNTAGNTFGEVHRAKRHAAVLNNADTPAIRAERRIRDLLHLHNPPMGSDAPQKEKAVVIHHDADAEELSTEVHEGGHEAVLKKHAQAKKWDDLSKEDQLLWKKKLSDAGMWAVEEGETILKSIFFGQIGGVIGGIAQGVIGG
The following text describes a protein:
Function:
Required for pre-mRNA splicing as component of the activated spliceosome. Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MDLKRKAMEGALAIVPAKKTRTDVVGFGTQVNNAIELLGGIRRTSKLQAPIMLLTGHESEIYCCKFSPNGKFLASAGTDRMILLWNVYGACDNIATLKGHSNAIMDLHFTTDGCQMVTCSVDKTLSLWDAECATRIRKYKGHQTFVNACDVSRRGPQYLCSGSDDGTVRIWDSRRKTSIQTLQSTFQVTSVCFSDTSEQVISGGIDNDLKVWDLRKNDVVYAMKGHMDTVTGLRLSPDGSYLLSTAMDNTVRIWDVRPYAPQERCVKIFQGNQHTFEKNLLRVSWSPDGTKIAAGSGDRMVYIWDTTTRRILYKFPGHGGSVNEVDFHPFEPIICSGSSDKQIYLGEIE
The following text describes a protein:
Function:
Core component of the smc-5/smc-6 complex. Involved in DNA double-strand break repair by promoting sister-chromatid homologous recombination during meiosis. Also plays a role in the DNA damage repair of ultraviolet (UV) radiation-induced DNA lesions. Promotes efficient DNA replication.
Subcellular Localization:
Nucleus. Chromosome. Note=Nucleoplasmic in the distal gonad arm and localizes on chromosomes during pachytene, diplotene and diakinesis in oocytes.
Domain:
The flexible hinge domain, which separates the large intramolecular coiled coil regions, allows the heterotypic interaction with the corresponding domain of smc-5, forming a V-shaped heterodimer.
Sequence:
MGKRDIPSPNENIAPRTIGMRDVDLTAAPAKKAKLDTGERIAVSGRVASVKLTNFMCHANLQIDFKTAQNNCFYIGGPNGSGKSALFAAINLGLGGRGSDNDRGNTVKSYIKDGTTQSKITITLTNAGLNAHPDFDDLISIERTINQASSTYIMKSVKVTSSDNHVERIVSRKKADVDRIVSRFSIHLSNPAFWMSQDRSRSFLANFKPANVYKLYLESTNLENIRLSYIRFADALDECFALIQLKAGEILNEQKKLKRMQEQRDLQAKLDQDRALVASFCWKLLFCKVRDYNDQIELTLKKQEAQKTLQDETKKEYAKNRAARTEVEKKIQEFRDEVEVQDAEIAEAREDLDAKKRKVLEFEEKIRECEQSIRKKTSEKKYMERTIVNAKNEVRILLEKQGNQDLTKRLTKVENDYKDISQQRENMELGGESAKLREKLDTVITDYKRKEEEKYTIQRDINQLRRKIEQDMETMRRSRATKKDAINKFGSHMAEILMEINRSKSRFQTVPKGPLGKYITLIDPKWAFTVEECIGNLANNFLCSSHLDAEILRNIFQSLRIPAQDRPTIIVAKCNGRAYTNLHEPSSDFKSIYRVLKFSDPDVHNVIIDKSNCEQFILIEDKTEAMELMGSNYPPQNAVKAYTLDGSQAYANGPNSQYRFYSGRGGHARGTFGNDQGDVDEGALARLIEDTKSEAMRLETQDLRKQDHELKVIYNERDQTKAAIDEFDRKLSNLRSQELQKERQAKDLRAELAQTANEDQVENLNESIEEMQKKIPLIEDEVKDILKNVADITADMAPVIQERKEAEHTLAEIQKETRDFASKSQKLQNELSKYDDAGEILKIRLDKVKADEGVFFHTEAKLKSERDDAMEMVENDKKNHPMPPGETDPPDLSSFPSTTEAQRKIEEMQKAVDRATVGCDTTITLECVKDFKDKLKRLKYLCRMIEDVLIELKNLHAARVKAYPSLKKFTELKVCNKFQELLAVRGHFIGGLEFDHEKETLNVNVQSSKEKDAMAGRRPEVLEVEEVDEHSYDDDSDDSTGPRRKKSKKSGQKKKRVRDLKGLSGGERSFVTAALVMSLWEVMEQPFRMMDEFDVFMDMMNRKLVMDLLVELATKKFPHNQFIFFTPQGIKELNMVDGLQVFEMNRVRD
The following text describes a protein:
Function:
Synthesis of fructose 2,6-bisphosphate.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSNTGSARTEEFTKGTGYEATKPNNDTDDDAKQNYPSKEPHMKLGDYTEETSFVDDSIFKREELTPDRNSPANDVEKMEVPKPTPQWMKLKDEGKLGKHRKNRLRRPGRFPVRQESTIDIPGLTVSKRTENDSNNASYGIREKLIIILVGIPATGKSYIGSKLSRYYNWLKYNCRFFSVGDKRREEGASTYSMSADFFDIKNEETFKFRENVALETLEDLLHWMIHENGVIGILDATNSTHERRKHLYDRISKEADIGIMFLESLCTDDILFEENIKLKIKGPDYEGYDTESALKDLRERVDLYKKYYEPLDERDEQLPFLQYVKVINVGIKVVTHNIEGFLAGQAVYFMLNLNIQKRQIWLTRPGESLDTVAGRIGGDASLTPIGKQYAQDLANFMDRQRVLWQLRYTNDLASTNKRFSLSEASSFNVWSSVRKRAIETIEFFNPDSYNVKKIRLLNDLNLGSREGLTLREFSEKYPDEFDVIKRKDYAYRFSGQGGESYLDVIHRLQPLIVEIERSSGNILVVSHRIVSNILMTYFLNYHPEDIIDVGLPLHTLFCIESDRYGTTCMAYRYDAANRQFIKDPMFDLRKRT
The following text describes a protein:
Function:
Required during nonphotochemical quenching. Involved in NAD(P)H dehydrogenase complex-mediated chlororespiratory electron transport which mediates electron flow from stromal reductants to the plastoquinone (PQ) pool during chlorophyll fluorescence increase after turning off actinic light, in response to photoinhibition conditions (e.g. high light intensities), and upon long-term mild heat stress.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MAAAANTSAVFASPSQPLSSKRSFLYSSRIGPILRRFPRKKLDLQVKAVATTLAPLEEIKEYKLPSWAMFEMGTAPVYWKTMNGLPPTSGEKLKLFYNPAASKLTLNEDYGVAFNGGFNQPIMCGGEPRAMLKKDRGKADSPIYTMQICIPKHAVNLIFSFTNGVDWDGPYRLQFQVPKRWQNKPIEFFNEGLANELSQDGACERAIFPDSNVVPTRCTMIANLTVEGGDRCNLDLVPGCMDTNSEHFNPYANVDDGSCPLELSDSDE
The following text describes a protein:
Function:
Xylan acetyltransferase required for 2-O- and 3-O-monoacetylation of xylosyl residues in xylan. Catalyzes the 2-O-acetylation of xylan, followed by nonenzymatic acetyl migration to the O-3 position, resulting in products that are monoacetylated at both O-2 and O-3 positions (By similarity).
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MWSALFSHLREVHKRSGVKEEKLIMKSPPAAGEAGCHKPQATATNKMTVLQSPLGLRTILTSLVAFFIVVSSVSLLFDRGQDAQAQLAVEQHQHQEVLLKQKPASAAVGEQKSVVVDQSSLRSQEAQVQWTSELQDVATDSGDGGFDGEEDCNWSLGRWVYDNASRPLYSGLKCSFIFDEVACDKYGRNDTKYQHWRWQPHGCNLPRFNATKFLEKLRNKRLVFVGDSVNRNQWVSMVCMVEHFIPDGRKMRVYNGSLISFKAFEYNATIDFYWSPLLLESNSDNPIIHRVEYRIIRADRIEKHANVWKDADFIVFNSYLWWRKQRDGMMMKVMYGSFEDGDAKLDEVQMVDGYEIALKKLTEYLGANINKNKTRIFFAGSSPAHSWASNWGGDDNNKCLNETEPIQIEDYRSATTDYGMMDKAKEIFGTLEPKGIHVQILNITQLSEYRKDAHPTIFRRQYVPLTKEQIANPSIYADCTHWCLPGVPDVWNEFLYAYIMHK
The following text describes a protein:
Function:
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
Sequence:
MAKKALVNKAAGKPRFAVRAYTRCSKCGRPRAVYRKFGLCRICLREMAHAGELPGVQKSSW
The following text describes a protein:
Function:
During early embryogenesis, controls asymmetric cell division and the asymmetric localization of P granules of germline precursor P2 and its descendant P3. Probably upstream of tyrosine kinase src-1, plays a role in endoderm development by controlling spindle orientation during EMS blastomere cell division. Controls EMS spindle orientation probably by promoting lin-5 and gpr-1/2 enrichment at, and let-99 exclusion from the junction between P2 and EMS cells.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Note=Localizes at the site of contact between EMS and P2 cells in the 4-cell stage embryo, between P3 and E cells in the 12-cell stage embryo and between P4 and Ep cells in the 26-cell stage embryo.
Domain:
The protein kinase domain is predicted to be catalytically inactive.
Sequence:
MKIHHFLTLLCTFLPLTTTALTNSTPLSLLGPCYKRCVTKFGETKEQLTNAETISLEYDVSNNTEFSLCKLGCNSHEYTDLNLAAFRYGQLAYQKILTTVEDVPTRGTVLNDVFIVCLDTSFMPSNNSAPSAKRLLSGTVLLVLDEDVAKADNVFLIEVLARNADKSAVQVISQQWCYSSNCNITFNAPTEVSSFDVRLRVSTFDSNGQVGGINFSKWHNINQILTKTFVDMSLKSVVWKAEKAAANFVFNLTASDHVPACSLQMIYRSSLSSELLHRNFYLDHTLEVFVNNLDFDKIYTMQLAPSGTHDRSTPSLASAVIEIPPCRHLVDDYSMCAPPPVSSLSYNWNLSPTSEYELLIKWKLLNYMDGLNVTEELSIPVAYFLLNAHPLITANNEQCEKYEKIRRVVSYGLRELVFHVPDTDCNYEVEMTAVDTNQRISEVKKIQVFRFNVPPYVSFLQASDIPTSVELMAVVLATSAIFALIALFLLYRKRKRDKKARFQMYKDAEAGVSYDYVATTESLGSVVQIRSTNFRFEPVENIDGNIEAALAQQQKFEGGTMNSMFRTYYNLDHPVKVPAHMAEASSDEDNGYENIRYSYFGSELSDDVFEEDIYMTHKSLSIYCQDSPLTTPMAPIAPYEHFDDIPSHQYRNFQVHNFNERIEKQAYWLMATVVDVVRRELYSLKVPKDYTPETISAMRKELEFLRTLAPHGNCRRFEGVVIGRWDDLPRQVIGILIENTRGGTLRNYIAAVGSVFRNCSLATDHDSFASQQDMNSTQHPFDKLSTEADENNSKKVKIQEITDSLSIRFCQFAEQVSSALEHLHSAGSVHTRVTTLNIYLLHNYSDPFDMLPDQVVKLGNFGFAVQNSEDVVLDDNLQPPEVIKGEKYEARGDIWQFGLCLAEMCSLGDLEQSEVGTLKSGHDTFKNLPSTQVLRDAAKRCLSARTRPSASDLCGVFKSVNVAATV
The following text describes a protein:
Function:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Miscellaneous:
MISCELLANEOUS: Present with 16700 molecules/cell in log phase SD medium.
Sequence:
MASTAVMMDVDSSGVNDLHHSEKKYAEEDQVQELLKVLNEISKTTLTLDPRYIWRSLKDLSSLRNQELLNAETLCFTVNVLYPDSSSFKKNLLKFITSNHKSSVPGSAELRNSYPASFYSVNTEKKTIEVTAEINCFMHLLVQLFLWDSKELEQLVEFNRKVVIPNLLCYYNLRSLNLINAKLWFYIYLSHETLARSSEEINSDNQNIILRSTMMKFLKIASLKHDNETKAMLINLILRDFLNNGEVDSASDFISKLEYPHTDVSSSLEARYFFYLSKINAIQLDYSTANEYIIAAIRKAPHNSKSLGFLQQSNKLHCCIQLLMGDIPELSFFHQSNMQKSLLPYYHLTKAVKLGDLKKFTSTITKYKQLLLKDDTYQLCVRLRSNVIKTGIRIISLTYKKISLRDICLKLNLDSEQTVEYMVSRAIRDGVIEAKINHEDGFIETTELLNIYDSEDPQQVFDERIKFANQLHDEYLVSMRYPEDKKTQQNEKSENGENDDDTLDGDLMDDMSDISDLDDLGFL
The following text describes a protein:
Function:
Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MASLPKPVRVSPLIKLCRWTLLIVGIYHGATKRNRLAKIEAVVREEEAACKAKKDQELAVAKEIANEKELIANTPTFVTRFLNKYVESTGRKIRANGKQIAAVVKIFITIASITEIWSDGNVKAGQLSLH
The following text describes a protein:
Function:
Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A and HDAC1. Required for B cell lymphopoiesis.
Subcellular Localization:
Nucleus.
Sequence:
MDQTRKRRLNNRKPGLSQCKVARAEEPEDISESRDVNVTEPAGSNFSSIRASSPQSDSTSQEQHAACTQTSEDDAENNLIITFDKEQAGTRGMGRRKGLRRKKDAINEVEAQQNEVEDEIQPEVEIDRELDRELENKSRQHNLTSANVRSIIHEVITNEHVVAMMKAAISETEPIPVFEPKMTRSKLKEVVEKGVVIPTWNISPIKKPTEAKKGPQFVDIPLEEEDSSDEEYRPDEEEEDETAEETLLESDLENSSSSPRVSRVQRSHSESEDGASRSRLNLCRSRHLTVAATPMGPPPPPDTSRAPPECSFLEKLHAVDEELAFGTDCMDSYQSLGGASGEESLISFRTRSKRPLRDVPLGRLEAELRAPDITPDMYEFGSAPEDREWTQWLQGLMISDMDNDEEGDDEDDPEYNFLADIDEPDVEDYRNDKAVRITKKEVNDLMEELFDAFQDELGGQDDEGHEEEEEKEEEESPLQEPPGILENIQYEDPLADVLKQRYRTVREQLAAVRKRKALLESKGVSVPPACPQRSSSPITSMTLNAAQRLQLQQQIQQHVQLLTQVNMLSSTVKGLETEASTSRQFLLELQMFGQRGEHNCGRAEHGFFTSIFNACNLQGAVSLLEELDQSLKGDPAVLSPCLPGCQFPASLAWLMATRSVFLYPELLPTIQLRPSKFKGPFTSAEDCLVVLGHKHLRGTLHPLQMTCRYLLATRSFISVKSHIRDACQKPFPSVIKTYFMAGKCPSMPLASKRVSPCDQRPPVEREQSLMPDWLSKNLKCIYKHVRTYNQASGNPQTTEATDPAGPGPHFCFPPGMRYPLSLPEDLAQTLEASALSAFKKKKDKTDKSAKPLKPPPSAEKLELVLNQLPAILPKTLSLSRPQPNPCLPGNRAITGPFILSRVPPVGSKQARAIATSPNISTTFKPSSSTSAPVKNAVETPMGISCSAAQRDIIITLPAAVTPELKSYPSGHITVNQTQIVTSNVVEPAVPRASNLIISFQPPQVANTFICPTPIINTNVQMPQNHISQRCGTLPKLLPKVSGGLAQVCPKPVNRFVLLPSGNVFANSSFGHQRAGQEQTLKQSSALKCKHVKLMRQQTSQDSLHSADRLKGDQSQMSFIQETPNDGFEETAEAELNDDDDDDDGGIVENEEEERGKIDSIEMSLTLSESSGSPMPSIDGEDAEMEMEKPEEQKEKEQEGCNRLFGDEETGGADNVSGVRLVPELQETMEKFLHLATKTVSEKEGRSNIKSKHQPSGSYWTQTERKTVLHNDASDHDPYRDAKDIAFAQAYLEKVYEVLHQVPGKVDEFLCILSDFVKNPESHTSLQLLMRLKPILEDWPELLQDFAAFLHPDQARECGLLAEQQAFERSRGFLRQLESTFGEQSYLYRKVVHILQGDQSQGLADLKEIKAEMALLLRDHTDLLEEFWEYFKQIYPQVQENVETNQVLEEKQPSQPSRNMLADKKLETDKTSIKHRRKTNKHAQMAEMRRNKVKNSSAMLDKDSEASLGDSQQSLFNATGSSVCAKNISHTSAGKKVVLWTREADRVILTTCQQRGAKQTTFHAIAAQLGNKTASEVSERFQDLIKLFHKSSKLHHTPDNWTQ
The following text describes a protein:
Function:
[CLE6p]: Extracellular signal peptide that regulates cell fate.
Subcellular Localization:
[CLE6p]: Secreted, extracellular space.
Sequence:
MANLILKQSLIILLIIYSTPILSSQARILRTYRPTTMGDMDSQVLLRELGIDLSKFKGQDERRFLVDSERVSPGGPDPQHH
The following text describes a protein:
Function:
Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer-coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein.
Sequence:
MNEDKLESKWLFSLTESQKLYLLISLIINKKLPEAKFVYKLLDYTKGNWLSLLLRFLPETTDPECYIPYIDIDSHYGNIKASVNDIEPIVLPDEELCQLRLTNMKLWNCKLPSLKDEAEFYSLFSKKIVEETDLVDLAYQLTKNSQAPAEIQQWNSGTFTVFHKLSQFAAVPINLEEMEAATIRDVISLAFPVLDSKNCVFIMDEIITVFINNSSNDPNLISENWDFVWKKLLQLVKTDGLAVVHTLVLNWNTIEPKLFLKLAKVALASCYISDDSSLYSVSLARDITEAIQNKLNFSDVNFGDLLKKPHDFSADGLLSLQNDLTTPSSLSTSLLMEITKAIALLTQLKVPAPTFKTSVSISCSNFDSQIKYLENVLLNALGTIQSPDYKDWHDLYSYIERFKQLSLFFLNISEDAISVVFLKQMLQEKSFLALKQMRNEIGLKDIEPKVLIDCLKTSFYENFRAASNMNKNRGKLALACKVLDVFVDCEPTIDLRRRLNSLVNACSLIQPFKLILEPGKPLSPSLVEANLNPDKLIKTIFSQNPSAYTLYDDILALDIELHKAAGDFDYSQVFTELRRITEHMITLTIDVSLEKDDIEYAKQIVEDRLMTLAEASEDVKFFLYEIAYKIGKFPSNHPNAKVIRLDMLQIAIANAPRQKLDEVVSYWTDFQSNSKVLEENLNTTDVEFHSSKKIKDYEDLEDANFDEEWSKAADLMSDDPENQVLYEGNLNSSLSLNEDPSVSDENLTQKVTSKLTNGLGWVLGVPPRK
The following text describes a protein:
Function:
Negatively regulates cell proliferation and cell migration.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: No signal peptide; MISCELLANEOUS: [Isoform 3]: No signal peptide; MISCELLANEOUS: [Isoform 4]: No signal peptide.
Subcellular Localization:
[Isoform 1]: Secreted, extracellular space, extracellular matrix; [Isoform 2]: Cytoplasm; [Isoform 3]: Cytoplasm; [Isoform 4]: Cytoplasm.
Sequence:
MAQSRVLLLLLLLPPQLHLGPVLAVRAPGFGRSGGHSLSPEENEFAEEEPVLVLSPEEPGPGPAAVSCPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
The following text describes a protein:
Function:
Aminopeptidase with broad substrate specificity. Has lower activity with substrates that have Asp or Glu in the P2' position, or Pro in the P3' position. Lacks activity with substrates that have both Pro in the P3' position and Asp or Glu in the P2' position. Lacks carboxypeptidase activity. Lacks dipeptidyl-peptidase IV type activity.
Subcellular Localization:
Apical cell membrane; Single-pass type II membrane protein.
Sequence:
MDSEAGYGAILLGSDRPQNFEEDQKTMSKGRYIILAVLCGAVALGVGVIIGWFSKSGLTEEDRVALDKFRALVRGADGTVGNTIMDEIDPERIRENLRELTRRPHMAGTVPDLEMAELIKQTWVDNGLDDARLVPYDFLLSYPPMGEMSENNTAVTVDEVGFVFEDTRTSHIEPELQGDPDAPQFFYAFSPPGNPEGELVFANYGRPQDFDYLEKNASVNCTGKIALVKYGREGRGAKATNAAAVGAAGVIIYPDPADVNVAGGAVYPDGWFLPGTGVERGSALSDPGEPLTPGYPATDYAYRKPLSDVDVFPPIPILPISYNDAQEYLRRLTGEEVPPGWNGSLPVTYRLGPGFTDDWAARKVRINVYTNTTTQRVYNVIGVIKGRVEPDRYVMFGNHYDAWVQGAIDDTSSTAISLELTRVFGNLVKEEKWRPRRSVVFAAWGAEEFGLFGSMEYVEQYAKLLGERLVTYVNMDVGVAGNYSLAVGASPSLQNAIYEATKRIPSPHNTPDKTVYDDWAQGQETPYIGGITLSTDHSSFALRVGTPVMTMAYDYDKTGYPTGTSYPVYHTGYDNMDVMERFVDPDFSVHRALTRTAGELLRYLSDEVLLPLEWKQYVTVLTASLNATLTDYGTSLEEQGISLDGLTSAVQNFSDAAAEFQNKLDRVDKDNPIQARIVNDQLVALNRAFIDPNRQHVFFKHILFSPPYCTLGTSNSFPGIIDAMCGGPQGEGWEEVKKQVASIAFTIQSAADVLNDVDSIAGPT
The following text describes a protein:
Function:
Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs. Is a critical activator of BACE1- and ADAM17-mediated pro-neuregulin ectodomain shedding, involved in the positive regulation of axonal maturation and myelination. Required for proper functioning of 2-oxoglutarate dehydrogenase (OGDH) (By similarity).
Subcellular Localization:
Mitochondrion. Cell projection, dendrite.
Sequence:
MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPITDIRAFTTTLNLLPYHKIVK
The following text describes a protein:
Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MNDTEVDYLEINCHEDVVWSAVAELLKNNAVQFHDTNESIIRNPGIESKLQTLTALYNNIQAIDKHISTLTDEFIQDDLDTTTDFQNHEPIINQFQLISDTYTQSINEYTSLHKNYKKIEIELKILNFIINSTDARPDNSSTDLSPQQDRSVYLESLLSNSNAKHIICGIIEEEKFRKFQSNVKQISAGKMEFKNSKYNKFKIYSIRTDENIRNSLKTVCNEWSILTMCFDDIETVAESIFNKNQKLNSVSERMEESKQRFINLIHTNLENYKKYRNLIKKLYKICSIISTSNYDQEKNRYTIYCWSLPKDFINIRKILEKSNRTDKIIYMDACNPTKKNYTNAPSHFEENKFFKTDKKFHINPNYFIPFHFALFGIIMGDFGFGLLALIYSLFLKLTSKFENKHFVIPIFSMYGGLIYNQFFGIPINFFPKSKFYPFGLKPSIYDMPKSFSKISLPRFAIMFMILAFNQIYAIHCKLVKLNKKISTITEYINFVFFCISFLFIPLLVTVKIFIFSITKKSDILIHIAYIFVYKDSSVFDMIYISIWYFSLFMYLFVFPVFKLVPFCHNAIEFLWTLFGSLSTLLVPVCSLLLPFLALLTNIVLTFLLNLSWNFYLRTFAFTFFFFCFCILLLIVFRGVYFLANLVAYIPPYAMFYDDHEFTHYQPSSFENEIQDL
The following text describes a protein:
Function:
Aminoglycoside acyltransferase that attaches the (S)-4-amino-2-hydroxybutyrate (AHBA) side chain from the acyl carrier protein BtrI to the aminoglycoside ribostamycin in the biosynthetic pathway of butirosin. The AHBA side chain protects the antibiotic from several common resistance mechanisms.
Sequence:
MCLTRYDEKFFDCRKSQIIAYLDSQQVPVIPLFYNSYQSTAEIYRQIFIENKSKWKYSEPSFSDDDLLRKGIRPVRASFPDFSQASDCLKDLLARHKLVFVWGDEYCLPYRKEAFQAIHSTHSLVVTGYDGENKAYYVEDWDGLYGYLPAVHLEAAFDSLSRQMRTLLVLELNDEEMRENKQEDTDLFRKWLQAFEDDYIFYDRVLLDMRDYEENRLISMDHGLRLIAASRHVFSKFLHYIDDAPEEVGLLIRNHQLANHIAAIVRRYIIAKQIDWDGAACKIRQLREQEDDFMRKLKSRYG
The following text describes a protein:
Function:
Enhances viral DNA replication and virion release. Mechansitically, optimizes viral DNA replication by interacting with host GRB2 to inhibit the negative effect of ERK signaling on B19 viral replication. Plays a role in viral infectivity. Induces apoptosis of primary erythroid progenitor cells.
Subcellular Localization:
Host cytoplasm.
Sequence:
MQNNTTGMDTKSLKNCGQPKAVCTHCKHSPPCPQPGCVTKRPPVPPRLYLPPPVPIRQPNTKDIDNVEFKYLTRYEQHVIRMLRLCNMYQNLEK