lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.
Sequence:
MPPRKKETVMSEFERKRLENIAYNNAILSGISTTADKIIPKPAPPKPKRASTPRVKREPVKKEAARPTRQSSRLAGLEADSAVLKRKLDVEAEEEAAKAKAKRMRVSGDLNLGDITVEGRKWESSADGLALLKGLGVRGAQPGVRTFTEKDVKHTKDKGLKDLRLRMSGLKLYEKWAVNDIKIVPQRIYSMCFHPTEEKPIIFAGDKEGAMGVFDASQPTPKIEDDDEDAEYPDPIISAFKTHSRTISSFHFSPTDANAIYSASYDSSIRKLDLDKGISTEIFAPSSSSEDLPISAIDIPTTDPNMIIFSTLHGSLGRQDQRTKPSSAEIWGLTDHKIGGFSLHPRHPYLVATASLDRTLKIWDLRKITGKGDLRHPALLGEHESRLSVSHASWSSSGHIATSSYDDRIKIYSFPSAGEWKAGHDIPAKEMQPTVEIPHNNQTGRWVTILKPQWQRNPQDGWQKFAIGNMNRFVDVYAEDGEQLAQLGGDGITAVPAVAHFHPTKDWVAGGTASGKLCLWM
The following text describes a protein:
Function:
Catalyzes the phosphorylation of thymidine monophosphate (dTMP) to thymidine diphosphate (dTDP), the immediate precursor for the DNA building block dTTP, with ATP as the preferred phosphoryl donor in the presence of Mg(2+).
Sequence:
RRGGPPRNPVLSREEGRGAWSASGVWPKRRRRAEPQATPLRDAPGIGAAEAAGPPRRAPRPPSAAPPQTDQRSTEIGKLLSSYLEKKTELEDHSVHLLFSANRWEQVPLIKAKLNQGVTLVLDRYAFSGVAFTSAKENFSLDWCKQPDVGLPKPDLILFLQLQLLDAASRGEFGLERYETGTFQEQVLLCFQQLMSEKNLNWKVVDASKSIEDVHEEIRALSEDAIQNAAQRPLEELWK
The following text describes a protein:
Function:
Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.
Subcellular Localization:
Cytoplasm.
Sequence:
MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNENFSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFADTYLKDSSRHCPSLWAGTNGGTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNGGE
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MSRFGAKKGRKLPGSEFTWDGTDANGEADTAPTPLFPKYNIPQPRPLSAREKTQVDLYRTLRERFHDGPYYSILGVSAGAAGYTGSSKANFDPFNGMQSYSGKYQKKKRLVPKIQGRPYVMKFFPRELWTTIQPNYKPDGILDGYVPQTLQTGTKRGFEEDDEDEDSAKRRREDGEEGEDLENNGLLEDEEDQEGEEEIEDDDFEDDDDEMGGDYNAEQYFDGGDDEYGDDGFGDGGGGGDEDTY
The following text describes a protein:
Function:
Binds to the consensus DNA sequence 5'-YCAGAGATGCGCA-3'.
Subcellular Localization:
Nucleus.
Sequence:
MSSTRPFCFVCGKEKSVGVFQLIEGCIVPGTFKPIKDILKYFEKIINQRLELLPNSAACRDCLEYLFNYDRLVRNLSQVQRQIADALLGCRQVEGKAETKQQAAKRARVQVPAFKIVQATALKEPERQPGEEDECEEFMKEEMLDEEFQFSEPDDSMPSSEEEFFTETTEIPCHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAEAKEATVTFF
The following text describes a protein:
Function:
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSLHEHLRPIPEPFSLTLLLGTRETPVTFLFHYYLYHALKAKESTCFLTFSKTLDEHAISMRKWGMDIKTKKNFFFIDGFSMLFAPISKPSKVQAPETKNHIKSVFAPVIQCVEENDFEFENSTIIIEDIDILQSTHALDSTKIQQAILELRKCFSRVIVNVTLGAPLPQQKSLGSSIGHMATRCISCRPLTSGSARRITGFLRLSRMPNHFRSGICETPEDDDKELLYEVTEAGAKVYSKGQVTLQL
The following text describes a protein:
Function:
Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths. Exclusively shows endopolyphosphatase activity, cleaving inside the polyP chain. Together with PPN1, responsible for a substantial fraction of polyphosphatase activity that is necessary to mobilize polyP stores in response to phosphate scarcity.
Subcellular Localization:
Vacuole membrane; Single-pass membrane protein.
Sequence:
MEDKRKRRAATLSTALILFVACCVYTLYIFKFDNPRLSPPVSLLPTISTLKKIEHVTDLNKEYVFVGDVHGNYDEFIELIDDKIGGLGENITMILLGDFIHKGPDSDKVVSYILNHKDQVKCVLGNHEILVMMAYLNPDFSKWVRRPKLMTPLTFSTETNFIPQDISKISNAHGRLARELGFSKLSQLAEHCSMAIELDLDITGDILFGAHAGMVPGDFMKPNQIPGVSSLSNMKYVDKKNWSKTSREKENKNYVRWYTLWDKYGDHFSNAKVFYGHDASMGLNLRRQTKGLDTACIKNNLLSSMKVKYDIKKGQYDYELIQVQCS
The following text describes a protein:
Function:
Involved in double-strand break repair via non-homologous end joining (NHEJ); the repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity.
Subcellular Localization:
Nucleus.
Sequence:
MDEAKETVFTKPQNHSSTLEFYDFVTTLLEPLSRIGKTRKSKTSNLDPYELKRKILLDYFNKWRQHVGPDLYPLLRLMLPDLDRERGSYGFKEFGLGKLFIRAMHLSPTSEDAKSLKNWRGSESKHTGDFSTMLQDILQRRAYRTFPGAFTVGDVNALLDQLADASSEDTRVNILEQFYRSLSPLELRWLIPILLKVRKYGTSEKFILSVFHPDAARLYRLCSSLKRICWELYDPSRSLDETETDVEVFSCFQPQLANFKKKDLHQTLEAMGNKPFWIEEKLDGERIQLHMSSGKFQFYSRNARSYTYAYGSSYFDEQSRLTQYIIGAFDKRISQIILDGEMVTWDPVLETVIPYGSLRSIFEDSSSHSSYSPYYVVFDILYLNGKSLVKYSLESRRRILEKVIVRESHRMSILPYKVGSTIEDIEAELRNVIQEGSEGLVIKKPSGSYHLGERMDDWIKVKPYYLQGFGEDLDCLILGGYFGRGKQSGKINSFLCGLRMDYTPKDHSEKFQSFVRVGGGFTYFDRDIIRKETEGKWLPWSSDALEYMELAGTKQDFEKPDMWIHPKDSLVLQIKAAEVVVSNRFKTNYTLRFPRLEKVRLDRSWKDALTINEFFTLKNAVEKQDNVSFHVNKKRKVSQKREKQKKFLYDEPTFKKEASPHSDVLKNLHFVVLPPTELHETKAGLQQIIIENGGLIHQGVGNFGKERLFLVADRVSTRVSIERSKNMCTIIRSQWVMDSVNNQRLMPQWSYLLFSKDEKYSWKTALESLSAKSLSNLLVELKQLDLSKEYSKISDDTSILNLTISKEEASFVGAFPFLKFTVFLDLKGIENSELYDVRMGQYRLTKCILLWNGATIEKDISSKKLTHVVMFVEDSTRLEQLTKACELYQIEPKFVNFEWVVNEWKKASTNILG
The following text describes a protein:
Function:
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MAYYHLSNVDHEKVQGEGWHDERSLVTHQGIHASCWTEASSGNITDARFHRGIDETRTRYSSTFLLDVVDHDKAYEKLGKSDGEHSCYGYSTFKAMEYIMNNGIPKHSDWTFPRKCNNYIPRLPSHANRVHVLNDVRCFTDVHRAIHYLKDQPIIGAIALFSPEFPDIGGVSVYLCSSKFFFFEIFCLCVSDALIIFTFQNLEYLSGSNFTDVGRSNPLGVMKVTNVNKLTSAGCKVKIWIADWFAQLNNKLGGDLEKIKVVGEYFKEIWEAGGMNPEKVEFLWASDEISTRGNTYWPLVMDIARRNNLRRILRCGQIMERSETEVLSAAQILYPCMQCADIFFLEADICQLGMDQRKVNMLAREYCDDIKRKNKPIILSHHMLPGLRQGQEKMSKSDPSSAIFMEDEEYAVNKKISKAHCPERTVAGNPCFEYVKYLVLPRFNEFVVENEKNGGNKTFTSFEDIAADYESGELSREDLKKALIKALNIMLQPVRHHFKTNERAKNLLKQVKVINCFPLCVYGFTNHIACILT
The following text describes a protein:
Function:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Predominantly located in the endoplasmic reticulum and in the cis-Golgi.
Sequence:
MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFIVPAYTEQSQIKGYVWRSAVGFFLWVIVLSTWITIFQIYRPRWGALGDYLSFTIPLGTP
The following text describes a protein:
Function:
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLVLKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
The following text describes a protein:
Function:
May play a role in microtubule-mediated transport or vesicle function.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSLAVADKLLKNFEALKNFREGIPVTDTNPLAKKKEGLLPIKDRISHINSIPELLCSTSIKGLQEFPKLLAIGIDTLLGSCDEDESDVRLVAGEALNKLIKGLLDSNVGRLLVELYKEIKKNGSARSLRAAIQRFGEICHLIRPQKCRICMRTEEAIQETLAVAVQKIFPVLGSFTSDNEVKQLMKAFLPNLRADQAMTRRTAGTSLAIICHHSRKPSMFHEWLLNILLGMVLPFQEVKAAPVYLGVLNCLRQIIPNLDDMSSHEEIMRGSFGVHMAPRGSRLSEAQGINIKQLLQMYEVLMHCTKHSNHNVVNASLETLQQLLRTPPAPLLEMLLSSDGIVPTIKPDTLPEVDMDISDDKENKEETASIATTETSDTGLGSEVRSDFGSTADLLASQSTKGLISVDREGLVTPQDSDEQLAQQIQHLGTSDKDTQNQTDEEEQGEEADTIGDLSTPPPSSPRERSVSDPGYFGEGEDNVDEQGVAISQTDTNQDDTEIPDELPRKETDRLSADLGELGQDLEPIRTESVSTQEVRILVESSFEIEAVACEGVPLVHCVRLMCSFLLTGRPGEVLPDSNVRVSVKSLALACIAQAIRLYPESFLGYVVPSCDSSDGVNVPDNRTQLVRDILQFNAHPDPQLRGALASVIGLVISAGMKKGRLDFEEWSNRSCEEFNTPVLSLPSLLSVLGCILQDDSPVAIRQACAAVKVCFNLLCSSPHCSHALDLVHTLAKLKNNSYWLVKVELLELIAEVDFRLIAFLETSSSGPDKNHVELNDWLLSEVVFVLLGDADGRVRHAAADCCVSLVPRLLFCTGDKRQNAVVQSAEYTVHSLSSHTYGNPVLSGPPRSKPSLEPSVSRLVSLATETLGHSTSKYLTVGCIHLLYTLSQSYPVSTLPGAWGCSVGQHCHSPVSPYFTSSGSPPRPGSPSMTCTGGGGPLSLAVACVTSSWLGYDLNAHQNLLLLSGQLLFGIGCSGVQASLKLHAGLPQEESSPAMESWNPFADLTLAPVVEKLVNHLVKILNIYAHVIDGNVPGAHSFKLSFPGQNKDKDKPSSQSPVPGVATPHSSPAGVVTSPSVTAVPKRLLKSKRAMSEADLANTPEKSPSKTSASPAPDTEQTPPHPPPPKSNIGTFHQSSHYMKLYDVIRGTHHNYQVFISYVQKQFEYVDAGQIRDCDTFLPYVFQFLVLLSYDCYQPKFNQAKAIVGMAKLFGLFMLHVTHITSSRIVRFSNMAFTTSYQDTSFLVKQFTSLTLFATHVFMSKRYPRITQATASLCHSSPTHPIIPEICKTVNKIIPTHPLSVLQWCKHVEEILGYLQACAKVEPCKAFLSVQQLLRAMFGINAVSQPELVQSPIYPECLADSQVTLPLKPAERVNSTGSGLYYGCFVQPLEDFRATLEKSFKEEETEGSIRKGLGSFFKKFRKRSGSLIRPAVKLDKGSPIHSFIRLFEPLVIRALKEYTLSACATLQQQVLSLLAQLIKLRVNYALLDADQVFISYVQKQFEYVDAGQIRDCDTFLPYVFQFLVLLSYDCYQPKFNQAKAIVGMAKVIQLCDGIMASGQSAKTHGRDMEGWCLCFYGLYNMPRAGNGGVVSMLLRLVQHAEGTQGLMERSIETLAYIHPRAGNGGVVSMLLRLVQHAECYQREDEEKWKKLSRQVIDMLLPLLAKQQALVETSFGLDALRTLFQSVSEVALHPADVLLKTLFFPVHLGELLTLERWLSMVLVLLHTVAANITEEQLLSRISQMNIKLDCLQGIVDDSLDSSPNEMIDTNDDQAPPAQLFGLFMLHVTHITSSRIVRFSNMAFTTSYQDTSFLVKQFTSLTLFATHVFMSKRYPRITQATASLCHSSPTHPIIPEICKTVNKIIPTHPLSVLQWCKVLQSIGYADLSYWYNLIGTCSSEDKTGESTMNREIVRQGATLLYCDLLMDKEETSLEDMVRLDDEPPVTRLIRTLHGSADGSRVLLETFIATHALGTSTKNLQTSFPKRLVRCLVGVHSSQTCLLLKILAEFFLNSHCRAIRRLVENNICKRLEANLPQTKGSPSETVNQELIAVCNLLASKKSIQRNPRLHSLVHRILQTEHRPYGAETRTQHLVSSMKDYTIDQEWFSRLVSHCCCATGPADSTVRPRPARESVQLLSALEFSTVCNIMASEDFDLHLLEDCVLYGVERTLHFTARRMNAGQETAVYPYENTEHFESTGVDHLLLAAKLTLFRHLASTVEEITSTVHSTGSGEVPLSSRITLDKSKLDRYCKDASACRRLLDLSAGLMSYCSVTSSLPRQCELSPDERACLCRFAFIPLAVMHQKFQASDYPSSDDLGTAVECLGKASEDYTLPVNGVEFVTLLCAAINHVYSLLRAVALHAHEHLTHGCEDDDALQESAEFQTITFACDQISDLVHYVHTQLEPGPSSSSVLPLFLMAPFKSAIVGLARRPLVNSYARTPPLVWKFGWMPTPEGPLKTELPPLPIEILKEKDVLNEFVIRVNILGWINRQQFEETWAALLGVLSSPPLPDSVTPETTLYPASGNCTASGYLHGPRHRDLPFLGSRAGKKLAVVRGIMEEEFITSCCAGTYLTHEELQHERSASLHRTNSFTQNHGSTAVWTSNKLLFDHPLYGLNVDRIPGFHDYTLGQLSVQALHSQAQAELQESPDSDDEAAVVVSVPHMPRPEKLDIRSCLQFLLELFEQWMSPYVQPRTPLMLLSEATKALVVFSDLFVDGHHFEWVLDTLLDLHHNHPTENDLLTQYLLPVICKALAFLKTEGPTAERVCKIVESSLRSPHVPLQVSLLYKPYL
The following text describes a protein:
Function:
Probable arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan. May function as inverting enzyme using UDP-beta-L-arabinopyranoside. May be important for arabinan side chains of rhamnogalacturonan I (RG-I), a major component of pectins. Cell wall pectic arabinans are involved in thigmomorphogenesis response of inflorescence stems to mechanical stress.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MARKSSLLKRAAIAVVSVIAIYVILNASVSRSLPSSSDLPRQLIREDDDDEGRAPIQPRVRVYMYNLPKRFTYGLIEQHSIARGGIKKPVGDVTTLKYPGHQHMHEWYLFSDLNQPEVDRSGSPIVRVSDPADADLFYVPVFSSLSLIVNAGRPVEAGSGYSDEKMQEGLVEWLEGQEWWRRNAGRDHVIPAGDPNALYRILDRVKNAVLLVSDFGRLRPDQGSFVKDVVIPYSHRVNLFNGEIGVEDRNTLLFFMGNRYRKDGGKVRDLLFQVLEKEDDVTIKHGTQSRENRRAATKGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPLIVSDSIELPFEDVIDYRKFSIFVEANAALQPGFLVQMLRKIKTKKILEYQREMKSVRRYFDYDNPNGAVKEIWRQVSHKLPLIKLMSNRDRRLVLRNLTEPNCSCLCTNQTGLITSI
The following text describes a protein:
Function:
Required for hydroxylation of C-4 in the sphingoid moiety of ceramide. Involved in the response to syringomycin (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MVTTVEMLTTWNPVTVSLVSPVIIYWVASAFFGFLHYIELPVFEKYRIHPPEEIARRNRVPQMAVVKAVLFQQLCEVVVGIALAMFEGYPEPIDEAKQMLRYEAFFSKNLPALLQVAPFAPKLAYNFIVPAFQYFFAFFIIDSWQYFWHRYLHYNKKLYNMIHAHHHRLQVPYAMGALYNHPFEGLILDTFGAGVAYLAAGLSPQQAVIFFTLSTLKTVDDHCGYVFPYDPLQMFFANNARYHDLHHQPYGFQKNFSQPFFTFWDHVLGTYMPPKSETPYEKKQKAKNAKKVN
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MSRALEREYRVGEEIGRGKYGVVSTCHSSVTGQCFAVKSIDKRVIQNDAVDSQCISNEAKLMQLVSGHPNVLSIFDVYEDDDFLHFVLEFCGSGDLFERITARPVFGESEARRIMVPLMEAIAHCHRLGVAHRDVKPDNILFNSYNQLKLVDFGSAECFGNGGLMSGIVGTPYYIAPEVVSGRPYDEKVDVWSAGVILYIMLAGIPPFYGESAKEIFEAVLRANLRFPRSIFASVSSEAKDLLRRMLSKDVSRRFSADQVLRHPWMTSG
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Sequence:
MTTDPNPENQGPGRRSSRQLAPEFTITPTQLSELHNPKSLAAYCALFGHSENGLCDALKTDKKNGLALADEEVRETARCRRFGANRVPERTARGFLRLMWEAFKDKTMIVLMVAAVISFSLGLYEAIGQPPELDDDGTPMAQVDYVEGLAIMAAVAVVVLVTAANDYQKERQFARLNRKKEDTEVVVVRNGDKHVISVHDLLVGDLLSLQTGDVVPVDCILVEGKCECDESGITGESDTIKKVSLAMSLQVYRTVAADNPSADIGSSDNGHSLVPDPMLISGSKLLSGIGHAVVTAVGPHSVHGKMMLALKSEPETTPLQERLNTLADDISIYGSVAAFLLFVVLFLRFLSYLPKGRLYHDLPSARKGSRFMDIFITAVTVIVVAVPEGLPLAVTLALAFATTRMTKDGNLVRVLRACETMGSATTVCSDKTGTLTQNKMVVVKGFLGSSHFDDISEDSNCAQSDALRQDMSQHTLNDILANIALNSTAFENKQVADPVITENPYHKPRRSLFPWSRNNKPKYPAPKDSSVQSAEFFIGSKTEAALLSLAKGSLGLESLQALRDDPHHIGIASIVQMIPFESSRKWAGLVVRLVDGNYRFFIKGASETIFKSCHYMRSSNDDVIKLSPQKHGEIFGLINNLASDALRTISLAHKDFTDISSWPPAELRDASDPSTASPDLLLGDEYVPTATDRPSIITNNNSGLILDGVVGIHDPLRPGVKESVKNCQQSGVTVRMITGDNITTGRAIARACGILSESEYADHECAMEGPVFRKLSRRQMMDAAPKLKVLARSSPEDKRIFVDILKKMNEVVAVTGDGTNDAPALTLADVGFSMGISGTGVAREASDIILMTDDFTSIVNAIKWGRCVSLSIKKFIQFQLTVNITAVTLTCVTAVTSTEENPVLTAVQLLWVNLIMDTLAALALATDKPDPHILERIPTGRDSPLIAVSTWKMILGQAVLQLIIAFVLHYGGRKLFYPHQVPFTGRDQKRLDTLTFNTFVWLQFFKLIVTRKLDEADGISDWRKRITARNLNFFQDLGRNYYFLTILLLIGICQVLIMCFGGAAFSIEPLTPGMWVTSILCGMLSIPWGALIRICPDEWALKLYPKRLMHIIQHIFGLKFLRGRKKSNNEDMDSHMETSKASDLMAYEAFEKARSEMLNFKESSKSGMATYLNPVNIIRKWSHESSDYQSFDDEHSLIASLTMVPTLVGGAVGGFSHISTPLLQGSPTSAKSSAKTYINKDV
The following text describes a protein:
Function:
Receptor for the cytotoxic ligand TNFSF10/TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis possibly through ligand competition. Cannot induce the NF-kappa-B pathway.
Subcellular Localization:
[Isoform 1]: Cell membrane; Single-pass type II membrane protein; [Isoform 2]: Secreted.
Sequence:
MFGFFCSLVSSLSRWFLWRRLLLLLLLLLLNLPLQVKFAMLELHSFKCPAGEYWSKDVCCKNCSAGTFVKAPCEIPHTQGQCEKCHPGTFTEKDNYLDACILCSTCDKDQEMVADCSATSDRKCQCRTGLYYYDPKFPESCRPCTKCPQGIPVLQECNSTANTVCSSSVSNPRNRLFLLLSPLSVLIVSVVVFRIIRR
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MASRLLRGVGALAAQALRAHGPRGVAATRSMASGGGVPTDEEQATGLEREIMIAAQRGLDPYNMLPPKAASGTKEDPNLVPSVSNKRIVGCICEEDNCTVIWFWLHQGESQRCPNCGTHYKLVPYQMVH
The following text describes a protein:
Function:
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
Subcellular Localization:
Cytoplasm.
Sequence:
MNHIQDAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLELNTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
The following text describes a protein:
Function:
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MRKMKKVMLTTGGTGGHIYPALAVADRLKIKGIEAVFVGSMERMEKDLVPESGHKFIGVDISVPRGLKNIRKYLKAIRTAYKVIKEEKPDAIIGFGNYISVPVIIAGILLRKKIYLQEQNVNIGSANKMFYKIAKMTFLAFDKTYDDIPIKSQSRFKVTGNPLRKEIDGLKYATEREKLGIKPSEKVLLITGGSLGAQEINNIVMKYWEKFCADKNLRIFWATGNNFEQLKKVRKTKKENDRIEPYFNDMLNVMAAADLVVCRAGALTISEIIELEKPAIIIPYGSIKVGQYENAKVLTNYDAAYVFTRDELDESMKRVFEIIRNDEKLKKMRIRLKPLKKPNAAEEIIASLDIWRN
The following text describes a protein:
Function:
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
Sequence:
MPKPEKIQKVEELYQKMLNANALIFTEFKGLSVADLTQLRGKIRPLNAEYRVVKNTLALRAIQRMYPDKDLEKFFVGPTAITYCYDDPFGVLKALVDYAKDHELLKFKGGIIDGEVYSADEIRELAKLPPKEVILSQVVGSISAPLSSLVWNLKWPVNKLVWTLDAIAKEKEKISINQ
The following text describes a protein:
Function:
Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
Sequence:
MSALLSADDLNDFISPGIACIKPTVTENRSQEASEYGEVEIQIDENGKPLEISKIDGATKNLSPAQISLADCLACSGCITSAEEILVAQHSHNELIKALKEKKTNNKIFVASISHQARASLATAYYMKVSDIDRLLVDLLVNQMGFTYVVGTGLGRKLSLINESQSVIERKEHGFQGPILSSICPGWVLYAEKTHPHVLSRISDTKSPQQITGCLLKSLTAHQLEVERDQIYHLSIMPCFDKKLESARPEQDPSLVSNDVDCVLTPKELVTLLDECKDKFSLTFDALSHSSGSLTDLYQSCAPANWPYVELSWSSDSGSSSGGYGYNYLQLLQSHLCLRDPQQYQPQNFRLESVAGRNKDIYELRLVYNDNQVASSAIVNGFRNIQNLVRKLKPTSSTTTTKTNPLVARRKARLSSKRSESGAQDVQQADASKCDYVEIMACPNGCINGGGQINSPTDEDQKLWVSKTLTRYGSIPMVDLSSDSSLTLELMAWCREFCINYNVPESRLLKTWFHEVEQPTDQAAILVGSKW
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MGQENLLPPQVGAQVGRPTLVLDLDNTLIDGSVSRPGLDQFLHAVKDLYEVVLFTAGTRECAEKIVDEIDRKYGSIAHRLYGDSCVDFVIKPAALLGRDMKRVVVVDDKPETFKQNVENALPIKPFFSKGNGDDEDEELLKLIPFLTSLAKMNDFRAAIFKWKKQKTQKSSSSDGTAAPKNKGGATTKKNCR
The following text describes a protein:
Function:
Suppressor of the MYO2 gene.
Miscellaneous:
MISCELLANEOUS: Present with 486 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MIAPDSQRLFGSFDEQFKDLKLDSVDTENNNTHGVSTILDSSPASVNNNTNGAVAASVNTVPGSTFRSNTPLLGGRHPLSRTSSLIDSIGIQRAASPFSSMKEPFIPQSSGVMSSSFWHGDHPESRVSTPVQQHPLLQRNESSSSFSYAANLGVNLSTHSLAVDITPLSTPTAAQSHVNLFPSSDIPPNMSMNGMSQLPAPVSVESSWRYIDTQGQIHGPFTTQMMSQWYIGGYFASTLQISRLGSTPETLGINDIFITLGELMTKLEKYDTDPFTTFDKLHVQTTSSDSINLNLAPYASGVAATGTIKATENDIFKPLTHDNIWDMDGGTTSKGVDIKLASATTISQTDESHKQEYKSTTMLEKGKKEKSESVAKALLDEQEKRNRELKRKEEARLSKKQKQKEDDLLKKQKEQKEQKEKEALEAEKQKKSEKTKKDTQTQTEGFKTSKDLPSLNSSSANPAPWASKVKVNNAIETSIKNGVSSTGKKKGEPLGLQQRNSKEEKQKEELKSVLNWANKSSLPSNQTIDIKSQFQKSPKGMKESSPLKELEDPNFIEEQKKLWEKVQSSSKQVKSTSSASTTTSSWTTVTSKGKAPIGTVVSPYSKTNTSLNSSLTAKTSTTSTTTTFASMNNVSPRQEFIKWCKSQMKLNSGITNNNVLELLLSLPTGPESKELIQETIYANSDVMDGRRFATEFIKRRVACEKQGDDPLSWNEALALSGNDDDGWEFQVVSKKKGRKH
The following text describes a protein:
Function:
Formation of pseudouridine at position 39 in the anticodon stem and loop of transfer RNAs.
Subcellular Localization:
Nucleus.
Sequence:
MAYNDTDRNQTEKLLKRVRELEQEVQRLKKEQAKNKEDSNIRENSAGAGKTKRAFDFSAHGRRHVALRIAYMGWGYQGFASQENTNNTIEEKLFEALTKTRLVESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPRGRDSEDFNVKEEANAAAEEIRYTHILNRVLPPDIRILAWAPVEPSFSARFSCLERTYRYFFPRADLDIVTMDYAAQKYVGTHDFRNLCKMDVANGVINFQRTILSAQVQLVGQSPGEGRWQEPFQLCQFEVTGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFENVKWIYDQEAQEFNITHLQQLWANHAVKTHMLYSMLQGLDTVPVPCGIGPKMDGMTEWGNVKPSVIKQTSAFVEGVKMRTYKPLMDRPKCQGLESRIQHFVRRGRIEHPHLFHEEETKAKRDCNDTLEEENTNLETPTKRVCVDTEIKSII
The following text describes a protein:
Function:
RNA helicase.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MLPISRRSILTHSLKPSTLSRSLSSLPASSWSSRPSSFSSASLSHFKKTISSRAHISAISLSAKHAFSVSASDRNSTAALRARTDVEASQPEEIEEDSEKPTTQPFSSIESYISPALYRAVTQSPFGYSHMSAVQDQLLSDLPNLIQATEGGQSRTKDLLVKAKTGTGKTLAFLIPAIESRLRDLEAEQARFKSQNPDATHQNLIQHMRRYEAETTGIVVMSPTRELATQIAQEAIKLTSHLKQFGIRLFVGGASKAAQLREFERGRRDIVVATPGRLNDVLNTSPAVRQNLATAKTLIMDEADTLLEMGFKEEIDEIVKQLPPKEERSTYLFSATISPEINRIAQQTMKKDTKIVDCVPTGETNVHAHVPQYFTVLPNPDQQVKHIFNLLAHDQLTNPSGKTVIFLPTTKMTQLFSQMISNFRRHLPWNSTGLTKVYEMHGGRTQRERENIAKDFRAGSGGGYQVLVTSDVSARGVDYPGVTRVIQIGVPTSRDIYVHRVGRTGRAGKSGRGDLILLPFEAGYVPSTLREIPIKPLSVSGLKDELTEMISKIDEAGQEQAPTILQQISQQRSMMNSRNSRYSNQRSEPKTNIQEVQMQLPVSTRVEAFDQNLRENIIPAIGEEAIRESFGSLLGYYGSKASDIRTTKDAILSGLKDWAVSGMLLPEEPYVSPTFLQKLGFNNDRRMARFGGRGGNSRGGGAGSSWGRGAGGGGNAWAARGASSSFGRSGGGGGGGGYSQGRAGGGGGYSQGRAGGSSGGYSQGRPGGGMRDREGPQFNNRGSSQFGAPSSRRGPPGGSFGGGGGGGFERNSERKFRSRD