lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
Miscellaneous:
MISCELLANEOUS: Present with 6120 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Sequence:
MGIKGLNAIISEHVPSAIRKSDIKSFFGRKVAIDASMSLYQFLIAVRQQDGGQLTNEAGETTSHLMGMFYRTLRMIDNGIKPCYVFDGKPPDLKSHELTKRSSRRVETEKKLAEATTELEKMKQERRLVKVSKEHNEEAQKLLGLMGIPYIIAPTEAEAQCAELAKKGKVYAAASEDMDTLCYRTPFLLRHLTFSEAKKEPIHEIDTELVLRGLDLTIEQFVDLCIMLGCDYCESIRGVGPVTALKLIKTHGSIEKIVEFIESGESNNTKWKIPEDWPYKQARMLFLDPEVIDGNEINLKWSPPKEKELIEYLCDDKKFSEERVKSGISRLKKGLKSGIQGRLDGFFQVVPKTKEQLAAAAKRAQENKKLNKNKNKVTKGRR
The following text describes a protein:
Function:
ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
Subcellular Localization:
Nucleus.
Sequence:
MTNENDDLSITSCDRCPRMVAFGNILLDISVELKDGKILHDFDLKPDDQREVPADKLAALVSVAVETCGNPIYNPGGSALNTCRILRALGEKNIIFCGAVGVDENGQILQQILKDCALNTCIQTLPDEMTGTCMCLISGDKRSLNANIGASLHFKKEFVSSRWCQSKIGVCKSAAHTNIDEDVRIFYIEGYFVPEKFHICTYIYEQYCKGTANLLVTNLNASYILQEFTTEMRFLVEHADLVFGNLAEFIALAQIYNCDDVDALARLLIKPYRKHNRNKILIATDGCRSVRLYYGAGSKFVAECYPVPVIQGNLVIDTTGAGDSFVAGFLYKFMNDESPTLVDCIRYGCKVAGKVIRQVGCNLPSSVPSSPSIAPSAKEGMIP
The following text describes a protein:
Function:
May play a role in fatty acid biosynthesis.
Sequence:
MNLRAAGPGWLFCPADRPERFAKAAAAADVVILDLEDGVAEAQKPAARNALRDTPLDPERTVVRINAGGTADQARDLEALAGTAYTTVMLPKAESAAQVIELAPRDVIALVETARGAVCAAEIAAADPTVGMMWGAEDLIATLGGSSSRRADGAYRDVARHVRSTILLAASAFGRLALDAVHLDILDVEGLQEEARDAAAVGFDVTVCIHPSQIPVVRKAYRPSHEKLAWARRVLAASRSERGAFAFEGQMVDSPVLTHAETMLRRAGEATSE
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MHLTTVSRSASEKVHLAVGDDPKQWWLTLIWASRCFIPQHNLLVLVHIHRPAIPTVLGAPVPASTLTEESICVHMTNMRKIIENNFKKCLQLYEVHAEILIIDNDKDVGVALVEVIKEHKITTLVMGAKRRKHGWKSRRAVALEKQADCLCNILYLHNGFVVDSRHQHTDRKIGVPSLRGCHFSGSSSNATKSSSFFNSCSTADAFDVEHLDDPSLVMNTTYIYNDSRFNAIIGLKSFDSFRELVNQQILAEHSRDLYQAFHIKYCDIFTGCQFIGGFDSLIGVDSQNLGDAHWKSIKSWPAVLDYIVSVLKTLKMQLLMQNHRACNGFTHDDLSEAVKIPIRRLFAVASMVSDLEVRKSPEKLFCVLNMYTALVDAAPTLRKVFSTKSIRDVLGELEDSVRGILKELKGLIHTYNSPKVVLDGDILPISGYLMRYIVLLVKHKVSLDTILGHDYTDSLLKVEGMSLTGGLVSGLITDLESVIDKQSKQCAASKGLRCIFLMNNIHFILQEVKQSDVQLTVKAKWFEKRQSCIKGYIKSYLSALWVPVTSTLEVARSVPPSKRARTNLLNFWYTAPSLTPLQSFASAFNEACSCQICWKVPSPALRDELRVKILEFVSRAYHGHLESQRQSAEQNANDFELEWKRKISELFEG
The following text describes a protein:
Function:
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate.
Sequence:
MNKISDTIIITSTSNEDEVDNNNNNNNLKEIDRSPRVNNNNNNILTNVNNNKNNTITSSGGSDSSSSSSNNNNNKIKKSKKHKEKEHMDSIVKLYSGKFDSWMVICHLFKYRDNPGIVDFLCNKMYNLEDKDIDFYITQLCILLINQPHDQKASFSSLARFILDRCASSFRFAIKAYWIFQAFEEDGEKNLFSIEGSVYLHSPSTSPKDVPMYSNDQIVPIDLDKIYNQSQYDDDDFDLSDDDGGFEIIKKNDHHYENDHHIENDPKKDINSNNNNNNNINNNNSNNDDNNNNEILPNENSDNSINDENNQYGNSNNNNNISGENDNIKIDINSQNKSDSNIETLNSTLCEETKTSPIKDDMENNNNNNNNNNNNNNNNNNNNNINNNNINNNNINNNNNINYGHINGSLSTLDGIGQPYISQPNDPIENITQILKRNRIIYKKVEEKKELATRLREFCEMSVITCSRPLITRPRTSSLPSPLISYNSGKIGGNYHKILSPSSVDSTSLISEDDKIIEKEEEDNVVEDDDDDEVNSEDFIPTATTTATTTTTTIPNHLSKTTSGVGINSNSSTPININSAGAGAGGGGEINHIGYDDISYLDKCKTPPAESKLSDHDFEFELSKSHRCDYLNDILSFIQKLAHISKILLPIPIDLRQAKLKHEISLLNINLPLGLYVPLWQSSNHHCVVRIPPEEVKILNSRERVPFLLVLEVIESEHEALSSNIFEVVSSYLQYTTGNSALKKDDIKRKYYSEKFKKSFLNSSINSTISNSSDSCTTETTTTSPVATSPTLPINIPHSKLINDGSNSISKSLPVTPTQSTVLNNLISTSTAISPPSQQQQLPSPSNTTTTTTTTTTNTNNTTTTTTTTTTTLSTSPTNEKILNENKQNSSPFGESWQEKIERYKKISPFGDYPNWRLYSVIVKTGDDCRQEQMAVQLISKFDEIWKETRLPLYLRPYSILVTSSGGGIIETIPDTMSLHNLKKSTPGFTTLLNYFKSTYGDPSGLRFRTAQSNFIESMAAYSIVTYILQIKDRHNGNILIDKEGHIVHIDFGFILSNSPGNISFESAPFKLTQELVDVMGGIQSGQFQYFKVLCVRGLIEARKQVDKIISLIEIMMSGPKMSCFVGGKEVIEQLKARFFLDVNERECSTLVENLISYSIDHFKTRYYDKYQSWLNGIYQ
The following text describes a protein:
Function:
Extracellular aminopeptidase that releases a wide variety of amino acids from natural peptides and contributes to pathogenicity.
Subcellular Localization:
Secreted.
Sequence:
MVTMKLLYLTSFASLAVANGPGWDWKPRVHPKVLPQMIHLWDLLQGAQQLEDFAYAYPERNRVFGGRAHEDTVNYLYRELKKTGYYDVYKQPQVHQWTRADQALTVDGQSYDATTMTYSPSVNATAPLAVVNNLGCVEADYPADLTGKIALISRGECTFATKSVLSAKAGAAAALVYNNIEGSMAGTLGGATSELGAYAPIAGISLADGQALIQMIQAGTVTANLWIDSQVENRTTYNVIAQTKGGDPNNVVALGGHTDSVEAGPGINDDGSGIISNLVVAKALTRFSVKNAVRFCFWTAEEFGLLGSNYYVNSLNATEQAKIRLYLNFDMIASPNYALMIYDGDGSAFNLTGPAGSAQIERLFEDYYTSIRKPFVPTEFNGRSDYQAFILNGIPAGGLFTGAEAIKTEEQAQLFGGQAGVALDANYHAKGDNMTNLNREAFLINSRATAFAVATYANSLDSIPPRNMTTVVKRSQLEQAMKRTPHTHTGGTGCYKDRVEQ
The following text describes a protein:
Function:
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain (By similarity).
Domain:
Composed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.
Sequence:
MSCLMVERCGEVLFESPEQSVKCVCMLGDVRLRGQTGVPAERRGSYPFIDFRLLNNTTHSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGTWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENVQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQHRRRGSGQDLAGPAPETLEQTEGATP
The following text describes a protein:
Function:
Cohesin cofactor dispensable during the meiotic division but playing an important role in DNA repair by homologous recombination (HR) probably by helping SMC5/SMC6 complex. Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Subcellular Localization:
Nucleus.
Sequence:
MAEDASPPAPQMTPEEVQAETELRLRDIGQRFGALPQEKEELLRLLSDAETWLSRVDQSPDEDMHNTLRPTMAILITNELLEHPDPNVKVAVTSCLTEVTRITAPEAPYDDDVMKDVFKRIVEAFAELDDMNSPSFQRRVSILDSVARVRCCVLMLDLDLDHLILDMFRHFFKTASMGHSEQVTNCMETIMVYVIQESDDVHAELASCLLQNLTKEAQETLPASFGIAERVLGLCKDKLKPVLLELLKGTPLDDYSNVVTLLFQDAGENNVDASGKDMAAEGKLSEKSVSDESPQETSKLEQDVNCVGQDGTSPISTPATTISNVGAPVDNVKSPGGPASSKQNQEVPSGDEQIKISDQLISGDKEVPEPVTAENEKLSDISSKKSHKLGSSTGPEMTEQSKVVKDNESLVASEELSPETNDGDKKQLTETSNRAAADSSKPVDTKPAVVKPKRGRPPAAKSQEKKSFGKKQGSNIESAKVDAVSDSGGRATRRLNKDDAKSLSTKAAEGESGKKQHKASMKLQKEDAASDKDTDEDISLKEMVSPTKMDKSKGQQEDSGGSKRKHLQEAEEATPSKKNKMLDENLVGSRIKVWWPDDKMFYEGVVESFDASSKKHKVAYDDGDVEVLMLRKEKWECIVEEQDDPDAASNMPRGRRAKGSSGQQMKEVKTGTPQSGSDSKNPPKKRGRPKGVRSSNNTPNSDSPVTPSKLKGQGAEKDNQEAPKTGSNSKKEGARPSRSTGKAKDDVVKASNKDETGSTDNSKDEAGSEDKDSKDEVKSSDVDGSKTNGLSTKRKPKEKEDESSEEEEKGSAKTFIRKKRRRKSRN
The following text describes a protein:
Function:
Amiloride-sensitive sodium channel subunit required for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNRGPPNPRMFKFQPNPKVKNRFQDEADLRSLRSFKTDFSNYLASDTNFLNVAEIMTSYAYGESNNANEKEIQCDLLTENGGIEIDPTRLSYRERIRWHLQQFCYKTSSHGIPMLGQAPNSLYRAVWVFLLLICAIQFINQAVAVIQKYQKMDKITDIQLKFDTAPFPAITLCNLNPYKDSVIRSHDSISKILGVFKSVMKKAGDSSAEASDDGVEYDMDGITIQAKRRKRGAGEKGTFEPANSACECDEEDGSNECEEKSTEKPSSDNDMCICAFDRQTNDAWPCHRREQWTNTTCQACDEHYLCSKKAKKGTKRSEIKKEPCICESKGLFCIKHEHAALVLNLWEYFGDTEEFSDISTEEREALGFGNMTDEVAIVTKAKENIIFAMSASEEQRILMSQAKHNLIHKCSFNGKPCDIDKDFELVADPTFGNCFVFNHDREIFKSSVRAGPQYGLRVMLFVNASDYLPTSEAVGIRLTIHDKDDFPFPDTFGYSAPTGYISSFGMRMKKMSRLPAPYGDCVEDGTTSNYIYKGYAYSTEGCYRTCFQELIIDRCGCSDPRFPSIGGVQPCQVFNKNHRECLEKHTHQIGEIHGSFKCRCQQPCNQTIYTTSYSEAIWPSQALNISLGHCEKEAEECNEEYKENAAMLEVFYEALNFEVLAESEAYGIVKMMADFGGHLGLWSGVSVMTCCEFVCLVLELLYMAVTHHITQERIRRRENAANEF
The following text describes a protein:
Function:
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Subcellular Localization:
Nucleus.
Sequence:
MQKLTTNNSDLCSGHPTSPYTAKSSSWWNSSGIQVPKGKRCMTLNLEMDSSLSHPGSLKHLETSLPEQDSCSSQSTGQSEEAAGVIGGSGGFQGSSAQPVDDETGRKGLQTFMKAGLPAGPTEYFSPLPQMEYGHSFTHVPCPYMAASYFGGALAPYGSQTMLTSQTLGLQQTRMLLPLDWTEEPVYVNAKQYHAILRRRQSRAKLEAQNKLVKSRKPYLHESRHLHAMKRVRGRGGRFVNTKNNNKSEEANISSGAASLQAGSSASSEVLQPENANIGHGISEVSSSLVAYLPESGNGHDSFGEFFRHSNFRLSVYGSDSKQNSA
The following text describes a protein:
Function:
Self-incompatibility (SI) is the inherited ability of a flowering plant to prevent self-fertilization by discriminating between self and non-self pollen during pollination. In many species, self-incompatibility is controlled by the single, multiallelic locus S.
Sequence:
MPLKLNKFLISLKMAIFSAQFASAVALIVVASLCLIEANQTGIGIEIGSRKQREFDYFNLALQWPGTFCQHTRHCCSSNACCRGANSPTVFTIHGLWPDYNDGTWPACCTQKSFDEKEISTLHDALEKYWPSLSCGRPSSCHGGKGSFWGHEWEKHGTCSSPVARDEYSYFLTTLNVYFKYNVTKVLNEAGYVPSNTEKYPLGGIVSAIQNAFRTTPKLLCKKGALEELHLCFYKDFKPRDCAIGSTSPNGRLYSSSSCPDYVSIPAYASMGLGSGETEISSA
The following text describes a protein:
Function:
Involved in the catabolism of quinolinic acid (QA).
Sequence:
MDYKNLVSKVLVESLVNQWIQEDIPNFDYGGYVVGEKVETAVLLCKSEGVIAGQPFVQGIYDKLGCQIQWKVEEGTLIQPIAQVAQVQGPVNKILMGERISLNCICRASGIATRARYLHNLAKSAQWHGEIAGTRKTTPGFRTVEKYSLLVGGISTHRFNLSSMVMLKDNHIWSVGNIEAAVKKARQACGFSTKIEVECRSLEEGCQAAKAGADIIMLDNFEPDALHRSAAALKVHYPHVLVEASGGITVDTINSYFVPNVDVISLSSTIQGCPVVDFSLKILKEETVPRIHKTKT
The following text describes a protein:
Function:
Acts as a negative regulator of disease resistance. Acts on basal resistance, age-related resistance and resistance mediated by the LRR receptor kinase XA21. Plants over-expressing NRR display enhanced susceptibility to the bacterial blight Xanthomonas oryzae pv. oryzae (Xoo). Binds to and represses NPR1/NH1-mediated transcriptional activation of LG2 in vitro.
Subcellular Localization:
Nucleus.
Sequence:
MDATTTAKRKRPAASDIADDAPTTVDEVSDAEVEEFYAILRRMRDATRRLGARPPPPRAPAWRPSFSWEDFADAPPKQAPPPPQQPADHERVAENATPPRRPAPGLDLNVEPPSDAPATPRSARAPA
The following text describes a protein:
Function:
The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.
Subcellular Localization:
Cellular chromatophore membrane; Lipid-anchor.
Sequence:
MSPAQQLTLPAVIVVASVMLLGCEGPPPGTEQIGYRGVGMENYYNKRQRALSIQANQPVESLPAADSTGPKASEVYQNVQVLKDLSVGEFTRTMVAVTTWVSPKEGCNYCHVPGNWASDDIYTKVVSRRMFELVRAANSDWKAHVAETGVTCYTCHRGNPVPKYAWVTDPGPKYPSGLKPTGQNYGSKTVAYASLPFDPLTPFLDQANEIRITGNAALAGSNPASLKQAEWTFGLMMNISDSLGVGCTFCHNTRAFNDWTQSTPKRTTAWYAIRHVRDINQNYIWPLNDVLPASRKGPYGDPLRVSCMTCHQAVNKPLYGAQMAKDYPGLYKTAVTQEALAGSAPASEAAPAAATEAAPEAPAQEVPAAEAVPAAAEPGAAEAAGSVEPAPVEEVAPAPAAQRL
The following text describes a protein:
Function:
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MAVRSRRPWVSVALGLVLGFTAASWLIAPRVAELSEKRRRGSSLCSYYGRSATGPRADAQQLLPQPQSRPRLEQSPPPASHELPGPQQPEAAPGGPSFRSSPWQQPALLPQRRRGHTPEGATALPGAPAAKGEPEEEDGGAADPRKGGRPGSSHNGSGDGGAAVPTSGPGDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQSPSAALGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNTEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNSEVSKEDQQLGRTPSFNHFQPRERNEVMEWEFLTGKLLYSAAENQPPRQSINSILRSALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQPFSKPFFREVEELDVNRLVESINSGTQSFSVISNSLKILSSLQEAKDIGGHNEKKVHILVPLVGRYDIFLRFMENFESTCLIPKQNVKLVIILFSRDAGQESIKHIELIQEYQSRYPSAEMMLIPMKGEFSRGLGLEMASSQFDNDTLLLFCDVDLIFRGDFLQRCRDNTVQGQQVYYPIIFSQYDPKVTHMRNPPTEGDFVFSKETGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTMQLAELWLEKHLGVRDNRTLS
The following text describes a protein:
Function:
Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
Miscellaneous:
MISCELLANEOUS: Present with 12200 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane. Endoplasmic reticulum membrane.
Sequence:
MSQQNILAASVSALSLDESTVHTGGASSKKSRRPHRAYHNFSSGTVPTLGNSPYTTPQLNQQDGFQQPQAFTPKQFGGFNNGSGSVMSTPVMVSQERFGASEASSPYGQSMLDMTAPQPTSHIVPTQRFEDQAQYLQRSFETCRDSVPPLPTTQFYCVDQGSCDPHLMSLSMYNIPESEHLRAATKLPLGLTIQPFSTLTPNDAEVPTIPLPMDGTPLRCRRCRAYANPKFQFTYDSSVICNICRVKMQVPGEHFAPMGPNGQRSDLNEKSELLHGTVDFLVPSIYNAIQEKELLPLHYVFLIDVSLLANENGSSLAMVEGVRSCIEYISDFQPNCEVAIIVYDNKLRFFNLRPDLDNAQEYIVSELDDVFLPFYNGLFVKPGNSMKIINDTLIKISGYISTDKYSHVPQVCYGSALQAAKLALDTVTGGQGGKIICSLNSLPTIGNGNLSLKRDNAHIAHVKCDNGFYKKLASDFLKSYISLDLYVTNAGFIDMATVGHPVEMTSGILKYYPHFQQETDAFTLVNDMVTNVSNIVGYQALLKVRCSTGLSVEQYYCDSSDNTDHDPIIPVLTRDTTLDVLLKYDSKIKTGTDVHFQTALLYTDIDGVRKVRSINTSGAVSNNIREIFKFINQNPVMRIMIKDVIKTLGDCDFVKIRRLIDDKMVEILTQYRGLVSSNSSTQLILPDSIKTLPAYMLAFEKSELMKPNAQSTRGNERIYDLLKYDSLNSAQLCYKLYPQIVPFHVLLEETDLTFYDANDKLLQINSSSINNLSVRASHSNFINGGCYLIFQGDTIYLWFNENTNRMLLQDLLSVDESLPVSQISLFSGTLPETGTSINQKASNVIKNWQQVVNKSSLPLVLLRPNVDQYYSNVMSQLLCEDKTVNRIESYDNYLVIMHKKIQEKLQKDDFIKVSTAATHENIHQKFVQF
The following text describes a protein:
Function:
Could act as a receptor for an unknown ligand.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MQPSPRGKTTGVYGAERIPGNYVKTLTGVVRGEELFCRPDLERPWRSADKQGSAATIALKEKEIEELMRLCSNLRTELSNTKSDSLFLEYSLTERTKLQLAEKQNEVDALQRRVEVLEKEKKEAAAATESQIRLLRSQAENESIGFKNEARVAIERCAELVKTFQKQLEDVKAAGVREVEFLEARFAAKVNEVTTELKSVRESKKALEEHYRAVEAQSSNMVHRVEADYKERLRSLEQRIEEQRLEYEAQLAKERKEKEAVVGESKRTTEKVAVLIADKEEFLQKQKLWNSYILSHLDTFYHSFIAVAPELAVDPTGVQLQQVPELYAPRCVLEDPESKVNVERIAYRVAQLKLLKALQPLGEAAARRGAKPPSAAQLDQVVESQERLWRALRELEDQQSELEATVRNFTSRLYFFSDNLEESLRCGPRPVPPPLRDVVFLCLGVPNGRVLWAANTELMRTSVQLLYSTLRLKMGEYGAYECYSDDVSMLLAFADATAACRFCTESQEWLMRLPWPAALLKLPEAQEERAEGGRLVYRGLRVSMALHAGEAYVEPSGIPLNGVYRNHYYGKAVSQLVHLCSLTQGGQIIVSIAAWNLCMRRQHELGAVVAKSLGTLPIVSFNSQSGVQEKQSIELLQILPIELEGRTFTPPGKAVVPPVSSLTGVKESVLAAEVAAVEAQRERVHDALAILQEECNSIQSSMGTLVARSRAALPHFHLLPPSEMVAQLNDLYSVMERVAVRAEELYTDLQDVAHAQEELGAQAQSIKDYFQQQEASAAREDDLRTKTEVVRRSMNHTLQLEKDRRRAETERLQLALQDRDQLIRKLHQESQSS
The following text describes a protein:
Function:
Can cleave 4-methylcatechol at lower rates than catechol, but has no activity with 3-methylcatechol, 4-chlorocatechol, 4-carboxycatechol or hydroxyquinol.
Sequence:
MSQAFTESVKTSLGPNATPRAKKLIASLVQHVHDFARENHLTTEDWLWGVDFINRIGQMSDSRRNEGILVCDIIGLETLVDALTNESEQSNHTSSAILGPFYLPDSPVYPNGGSIVQKAIPTDVKCFVRGKVTDTEGKPLGGAQLEVWQCNSAGFYSQQADHDGPEFNLRGTFITDDEGNYSFECLRPTSYPIPYDGPAGDLLKIMDRHPNRPSHIHWRVSHPGYHTLITQIYDAECPYTNNDSVYAVKDDIIVHFEKVDNKDKDLVGKVEYKLDYDISLATESSIQEARAAAKARQDAEIKL
The following text describes a protein:
Function:
Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MASNIPDLFYSCEICGLEGLSEDEFRTHTRTAHVDGNAVCPFCELSAVSPAELILHVNQAHLDYLTPESESNMTFIDDVSPSEYNGINGESSDNWNIPSLPSHNKTNINNINLSPKVNGGGELSPKNSTHGQGSPLRSSLALKLKSAAPRMQCPMCNYTSNSPNELEEHVNRRHFDVTSPSMGGTTSEIYSCPLCVKSFNSAPDLELHVNIEHRDVLSPASPPTHSCPVCGMNLDNASNSESAARHVESHFPATSPQPADRAALREREQREFEMLRAQYGMDNQGNFREQSVTNMQRAVYAGEMSVADYYERTLDLRAAESCGIDDGSSITRSIVPRVRAISTTAPNVVRTLLCTCVDHYASSYGDRGWGCGYRNMQMLISSLLTHTGYNERLYKLWQGQKPPRSSVPSISRLQSLIEQAWSQGFDIQGSEQLGCRLVNTRKWIGATEVVTLLSFLRIKCQLVDFHRPTGPGGTHPELFTWVLKYFENSVGGEFVPPLYLQHQGHSRTIMGIEVHRDGSLILLVLDPSHSPQQMAQFGDTNSSAVALRLLRKSEAAMKARQYQIVAVVGTIDSEQQYQQSKILRGTRIPQDR
The following text describes a protein:
Function:
Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX) (By similarity).
Sequence:
MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR
The following text describes a protein:
Function:
Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. Involved in immune regulation.
Miscellaneous:
MISCELLANEOUS: Ido1 and Ido2 are 2 distinct enzymes which catalyze the same reaction. Ido2 Km for tryptophan is much higher than that of Ido1. Ido2 may play a role as a negative regulator of Ido1 by competing for heme-binding with Ido1. Low efficiency Ido2 enzymes have been conserved throughout vertebrate evolution, whereas higher efficiency Ido1 enzymes are dispensable in many lower vertebrate lineages. Ido1 may have arisen by gene duplication of a more ancient proto-IDO gene before the divergence of marsupial and eutherian (placental) mammals.
Sequence:
MEPQSQSMTLEVPLSLGRYHISEEYGFLLPNPLEALPDHYKPWMEIALRLPHLIENRQLRAHVYRMPLLDCRFLKSYREQRLAHMALAAITMGFVWQEGEGQPQKVLPRSLAIPFVEVSRNLGLPPILVHSDLVLTNWTKRNPEGPLEISNLETIISFPGGESLRGFILVTVLVEKAAVPGLKALVQGMEAIRQHSQDTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSGWKDNPAMPVGLVYEGVATEPLKYSGGSAAQSSVLHAFDEFLGIEHCKESVGFLHRMRDYMPPSHKAFLEDLHVAPSLRDYILASGPGDCLMAYNQCVEALGELRSYHINVVARYIISAATRARSRGLTNPSPHALEDRGTGGTAMLSFLKSVREKTMEALLCPGA
The following text describes a protein:
Function:
Binds to the 23S rRNA.
Sequence:
MVVRREKKSRKMRGSRTMGWGIRGQHRDRGSQGGRQIGMHKEKWSWLVKYGKGWYGKHGFRNPTTKLTSAISLRKLNELLESGYIKIKEMDGKKIVDLNELGYNKLLGGGSISIPVTIKVGKATNKAIQKVKEMGGEVILSPTE
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MAALPTTPDSPAAQLERTEAGSECDPEQDGEEEEAKGQEMEAAMEEEAEDLAEELEAEGARAGPAEQAEQDDDVAEVVAEERSPVLGTQERLGLGRGGGDTESPALREKALQASQAPASPSHEDVDEDEEGEEEEEDGSLVSGSQGLVTFEDVAVYFSLEEWERLDSEQRELYKEVMQENYGILVSLGYPIPKPDLISRLEQGEEPWVPDSPRPEDGDIVTGVYTGAWFWTDDIEDHEEDDDEDFLAEVAEEENEPPGLWSAAYGVGDVPGTWGPDDSDSAQTPDGWSLDPGGLGVLAEGPEAKPFLPGREPGASLLAPWAFPSAVAAPAGRPETTCEVCGKVFPHRSRLAKHQRYHAAVKPFGCDECGKGFVYRSHLAIHQRTHTGEKPFPCPDCGKRFVYKSHLVTHRRIHTGERPYRCAFCGAGFGRRSYLVTHQRTHTGERPYPCPHCGRSFSQSSALARHQAVHTADRPHCCPDCGQAFRLRADFQRHRRGGGCSEPSADGPRREPCETVPTAGPEEAETGPEGPEEPEVGEADGEAEAEAEEREVAVELPAPGSKEDPEPDRRFLELGNGLGEGEGPSSHPLGFHFPVHPKSWLHPDGFPILGLPDFGERLQADRRPLPGPLGGRLSLVEGAGLACDPFGGSAGAGGGGGGLRAFAPAVGGLLAEPAPAALAEEESPWICSDCGKTFGRRAALAKHQRYHAGERPHRCADCGKSFVYGSHLARHRRTHTGERPFPCPECGARFARGSHLAAHVRGHTGEKPFVCGVCGAGFSRRAHLTAHGRAHTGERPYACGECGRRFGQSAALTRHQWAHAEEKPHRCPDCGKGFGHSSDFKRHRRTHTGEKPFRCTDCGRGFAQRSNLAKHRRGHTGERPFPCPECGKRFSQRSVLVTHQRTHTGERPYACANCGRRFSQSSHLLTHMKTHRGAAGAAGPAPAAPASKAEAPAKGPPGAGAGTGPGEHGGILLEFAGGTSFGSEPTTAFAGPSGAYEESVM
The following text describes a protein:
Function:
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MFRTEIVSDTTFTVLKRYEDLKVIGAGSQGIVCAADDTKTGNRVAIKKLSRPFQNVTHAKRTFRELVLMLIMKHKNTIRLLNLFTPNRSLEEFSELYLVMELMDANLCQVINLELDHDRMSYLIYQLLCGLKYLHSAGILHRDLKPSNIVVKSDCTLKILDFGLARITGNEFMMTPYVVTRYYRAPEVVLGLGYQENVDVWSVGCIMGEMIRGTVLFPGDDHLDQWNKIIQQLGTPPDDFLDKLGHSTRNYILSQHGNRAGLPFKVLFPDSLFPNGSEDDDDDNYTNQARDLLSKMLIMDASKRTSVVDALQHPYVRQWYDASECEVPPPTRYDHTIDDAKYPVEKWKGKDLHQEKLFLDFCP
The following text describes a protein:
Function:
May play a role in the regulation of cytokinesis.
Miscellaneous:
MISCELLANEOUS: Present with 8970 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MPMNNFLDEFNLFDSIITMMKNDPCCVEDYEPIVENLNRIFQRTFNDEEHRKSMANSQLFWERLRDTLEAMLLPASLNENSSIPYTRTVRGLILMMRNLAAENQEIPQKLLLQNLVIRGFLHATSEYVVDTPLIKHLYIACLTCLFNIQQNYSTVDMTTFPALLQFLQYPYGIKLEDGEEEEHFWLPYLFLFKTYLNNDEFSNEFFRDNDTPQKDYYCVRDRIFFDIVTAKFIQDQENSFLIEKGRNYLDDSKLEITSIDLSVLECISKSLTTASFGKYLNGLEERQPGKFTTLLQILQLVVTSKEDWNTYELTAIMSWCYPILQRLACKDIPAFFNKSCNDYAPSVAIQLHSTLLSCLDIISDLCKFNHVRKFLISYDSVKILVSLLDTFQKNLLRINFLKGNGDTVNEIKITDHEGNKIEDRLLIFNRVNTNESFIRADNFPHCKLVIIEILASLVYAHPEIQDQIRELGGLALILSNCVIDDNDPFIKERSIVCLKFLLKNNAKNQEYVKKMEAQDVVQDDALSKAGFEISVEKGGKVRLVSKEEDPGNENSEIISIDED
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MDFLVKKEQPIGLEDENDNDPLVMASCLDFKVAALKKKKKQKKMCFDHHELTDDRSSQILSMFRKYLYSKTQNDVVGKTNMEESEAIKLKHAARFTPRQASLLEQKLLRGIRKEEKQSEFDGKSSAAQLTIFYAGTINVYNNVPAHKAQAIMLLAGESSTSKPASVELPAKMETNGISSSVNLTSVCKLQADLPIARKLSLQHFLEKRRCRIISKSPYSSPATPRAEENSEETKPRADGDDSNAVHGSISLSPFPSRLGYFFPVSANKDL
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MTTSHRPQLEARSGAKAAAYTPTGIEHARLLPGHTTLKYRKFKEEENLRANCAQEDRSNDKSLEEAVMNEEKQDVVGSGNLQETRSEKDQKDSLQELLVTQKNKVEDKAELEGNEQLKGGNSSRRSWRKGTAFGRHKVTKETNIKEHATKKSASGYINDMTKSEYHQEFLHKHVR
The following text describes a protein:
Function:
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Regulates the inflammasome signaling pathway by deubiquitinating 'Lys-63'-linked polyubiquitination of the PYCARD/ASC adapter protein. Regulates the ubiquitination and stability of the ACE2 protein. Acts as a negative regulator of the G2/M checkpoint pathway, by preventing serine/threonine kinase WEE1 degradation, thereby repressing entry into mitosis following activation of the G2/M DNA damage checkpoint.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus.
Sequence:
MASRCPPDDFKIYYVLTECTDYSDSSSAKESNMAQQHSQGVTGLRNLGNTCYMNAILQCLCSITPLVEYFLSGKYITALQKDSGEAATAFAYLMTDMWLGDSDCVSPEVFRTAIGKIYPTFLKRTQQDAQEFLIYVLNELHEALKKYRRKKPHEKVTTKCYRKVASSESSIITRLFEGQLNYDIVCLKCENCTYKNEVFTVLSLPIPSECECSLQECLGCFFQQDTLTWNNQIHCAFCESKQDAAVRASIAKAPKTVIFHLKRFDCQGRMKRKLRTDIHYPLNNLDLSPYIYPLFRKHPKYSLCGVVNHFGDLDGGHYTAFCKNTVSQTWYSFDDTRVCEIPDSSVQTAAAYLLFYSCQPFSIPTPKCKC
The following text describes a protein:
Function:
Controls stomatal patterning.
Subcellular Localization:
Secreted.
Sequence:
MDSSRKYKRCGFGAALFVANIFFSLLSLHCISGAHGHQQRMKESVMGSEPPVCATKCRNCKPCLPYLFDIRGAHDDDDDSEPYYPVKWICRCRDRVFEP
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MAAKGNSADRNAPELNRVLSFYRNSTILLTGGTGFLGKVLLEKILRCLGVRKVFLAVRIKDGRKPAERLQELLKDALFDRLRQDATVEQLLERVEPVEISLEAGDGLGLGMDETTETRLLQQTDVIFNVLASVKFNESIKNAVDTNVGGTRRVLQLARRMQRLKAVVHVSTLYSNCDRTHIRERVYDDTLLRPEAVLNLSKLLSADEMDGLQHCLLGSLPNTYTYSKKCAESLIQQHFSDLPVGIFRPPIVLSTYREPIAGWTDNLNGPAGLCLWTVKGYVRVIHGNGRKKANLVPVDYCVNALLVAGFDVADRSMARDPAQDSRSGWETVQPVPVYNYLYDRPNLTWGRYMGTVSMGFDGWIKRLCWPHSYTIVPNRALFRVLSLCCHTVPAWLLDFVRQLRGKRPLYRRMAAKTNRFLETMAYFGLREWQIANENVVRLRTLLTPTEASLLEFDLSTVDWDEYFQAYIPGIRRYYLGELPAARDRTNPAQPLAWNRRIQFLCRLLHRLMWVLICLKLGHRLYVRRNLFSILIA