lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Negative regulator of the salicylic acid- (SA-) mediated resistance to pathogens, including the biotrophic powdery mildew pathogens Golovinomyces cichoracearum and Blumeria graminis, and the downy mildew pathogen Hyaloperonospora parasitica, probably by limiting the initiation of cell death and the establishment of the hypersensitive response (HR). Prevents ethylene-induced senescence. Binds to phosphatidylinositol-4-phosphate (PtdIns(4)P) in vitro.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein. Endosome membrane; Single-pass membrane protein.
Domain:
The pleckstrin homology domain (3-110) binds to phosphatidylinositol-4-phosphate (PtdIns(4)P).
Sequence:
MSKVVYEGWMVRYGRRKIGRSYIHMRYFVLEPRLLAYYKKKPQDYQVPIKTMLIDGNCRVEDRGLKTHHGHMVYVLSVYNKKEKSHRITMAAFNIQEALMWKEKIESVIDQHQESQVPNGQQYVSFEYKSGMDTGRTASSSDHESQFSAAEDEEDSRRSLMRRTTIGNGPPESVLDWTKEFDAELANQNSDNQAFSRKHWRLLQCQNGLRIFEELLEVDYLPRSCSRAMKAVGVVEATCEEIFELLMSMDGTRYEWDCSFQFGSLVEEVDGHTAVLYHRLLLDWFPMIVWPRDLCYVRYWRRNDDGSYVVLFRSREHENCGPQPGCVRAHLESGGYNISPLKPRNGRPRTQVQHLIQIDLKGWGAGYLPAFQQHCLLQMLNSVAGLREWFSQTDERGVHTRIPVMVNMASSSLSLTKSGKSLHKSAFSLDQTNSVNRNSLLMDEDSDDDDEFQIAESEQEPETSKPETDVKRPEEEPAHNIDLSCFSGNLKRNENENARNCWRISDGNNFKVRGKNFGQEKRKIPAGKHLMDLVAVDWFKDSKRIDHVARRKGCAAQVAAEKGLFSMVVNVQVPGSTHYSMVFYFVMKELVPGSLLQRFVDGDDEFRNSRLKLIPLVPKGSWIVRQSVGSTPCLLGKAVDCNYIRGPTYLEIDVDIGSSTVANGVLGLVIGVITSLVVEMAFLVQANTAEEQPERLIGAVRVSHIELSSAIVPNLESE
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MASSINNFEDNSNLDSSIETLLENLNQEYFTTALPCRSNEIEAISTFINNSYDTSRPIHDIHMKGRKPKQNDDIQPGILYITGNPGTGKTACVKYAIQTSAAAPYIKFSNCKTEKITLYKAGQEIPIIQVLDEVESYTDFAEIAANSIRMKYSLICISNASEDNSIIQKSSGLSLQQLKFNSYTAEELCQILTERIGGPCNNLVEVAIEHLAKTVLKDRGDARAAIARLATVLTAAIQENIKTISLKEMISLLSHPQGTIKFDLPLYQQIALAAIYLAGKNWVKKFNSIVAEKNLESFSDTKSVFDQLCDYPGLVKGNFKNPVAIVSKETIIANVDHLIKTVL
The following text describes a protein:
Function:
Required for 60S pre-ribosomal subunits export to the cytoplasm.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPKPKTARGILLTSNLPQLQNLIKRDPEGYKEEFLTQYNHYLSLLRLHSVASSTPSSSNDKSNELFADLITFISQVAQCYPEATKDLPMQLSGLLLGGESGTSNVVTGDLRKTAVKNLVMLRNKEIIDSIQLLQTLLPLLPTVPSTLRSIIRHTILTDIKTSNAKTKNHRLNRVVQSLLFGMVESGMGAEVVGDKGRNKGKGREKGGEAMWAVMMVKELWRKGVWTDAKTVSIVSLAAFHPNTKVQSAALHFFLGSENEDEDDSEDEDEVGEARRDVRKMEHRMEVSRGKRKKEKQVKQLKREASKKRKKRAEGAGVTPNFPALELLQDPQTFGEKLYDNLHRHDKIYSLDHKVLIMQLLSRVMGVHKLCVLGFYSYIIKYLTYHQLQVTLILVSLAQSVHDLTPPDVLTPVIRKLAQEFVHPGVGAEVIAAGLNAIREVCRRQPWCMEEDLLGDLIEYRKSKDKGVVTASRGLLQLFREVNPGMLKRRERGKAASMGLIGSQVLAYGHSADAAEGIEGLELLEEHYAKLRKEANGDVGDGSDVEMDVGEDDDEGWEGWEAESDSEADSNGWESVSSGGEDLEISDSEDESDKRRDKKDKREKKRLARGKGKAKAEDGETDEDEEMDDAVSVAATEATEASQTTKKLSLLAQQRILTPADFELLNELRLKAAKELAAAGGGSAAKRKLAALEASKRHVGEDEADRFLTEAEILGPRKKAKATWEERMESIQKGREGREKFGSMKGKKKKAAPSSSTNKEKAKNKPIMMALHSNRVVSKKKASLRDKQIRLRAAIEKRKKQKH
The following text describes a protein:
Function:
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
Sequence:
MLDQLTLCLLLNFLCANVLANTSVFNPCVSQNELSEYEAHQVMENWPVPPIDRAYKCFLTCVLLDLGLIDERGNVQIDKYMKSGVVDWQWVAIELVTCRIEFSDERDLCELSYGIFNCFKDVKLAAEKYVSISNAK
The following text describes a protein:
Function:
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Subcellular Localization:
Cytoplasm.
Sequence:
METKGYHSLPEGLDMERRWGQVSQAVEHSSLGPTERTDENNYMEIVNVSCVSGAIPNNSTQGSSKEKHELLPCLQQDNNRPGILTSDIKTELESKELSATVAESMGLYMDSVRDADYSYEQQNQQGSMSPAKIYQNVEQLVKFYKGNGHRPSTLSCVNRPLRSFMSDSGSSVNGGVMRAIVKSPIMCHEKSPSVCSPLNMTSSVCSPAGINSVSSTTASFGNFPVHSPITQGTPLTCSPNVENRGSRSHSPAHASNVGSPLSSPLSSMKSSISSPPSHCSVKSPVSSPNNVTLRSSVSSPANINNSRCSVSSPSNTNNRSTLSSPAASTVGSICSPVNNAFSYTASGTSAGSSTLRDVVPSPDTQEKGAQEVPFPKTEEVESAISNGVTGQLNIVQYIKPEPDGAFSSSCLGGNSKINSDSSFSVPIKQESTKHSCSGTSFKGNPTVNPFPFMDGSYFSFMDDKDYYSLSGILGPPVPGFDGNCEGSGFPVGIKQEPDDGSYYPEASIPSSAIVGVNSGGQSFHYRIGAQGTISLSRSARDQSFQHLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGKCSWQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK
The following text describes a protein:
Function:
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAVNGTALLLANVTYITVEILIGLCAIVGNVLVIWVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVISLGITIQFYNCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYRRVTTQRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEHQRNVTFLSCQFSSVMRMDYMVYFSFFTWILIPLVVMCAIYLDIFYVIRNKLNQNFSSSKETGAFYGREFKTAKSLFLVLFLFAFSWLPLSIINCITYFHGEVPQIILYLGILLSHANSMMNPIVYAYKIKKFKETYLLIFKTYMICQSSDSLDSSTE
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLVRFAIKNEYGLGVGELYKDGVESEDPKAVLDGVAVAGLVGLLRQLGDLAQFAAEVFHGLQEQVASTSSRSRKLVNRVQRVEASLPSLEKAILSQTDHLRFAYTPGSERHAYIRTERNLFICDDFPHYIMDSYEECREPPHLQLLDRFDSGGPGSCLKRYSDPTFFKRASSCSQVSNSETCQRERKTRKTKKRRSWQQSGQLPKSTPNLNGSSRMQFSSTGHGQSSLSHTGSTFDMTFKSDMGDQSDSHGSKDGVDFMECVSRPSISTRPDETKNKGLSTSLIEAEVNNNGSIHPDEQISVASDDKPCSNDAETIVPHSSNATWDELLEIVEPTDVTYKIEDTRQMPATNCSPHELELKLVNKICVNQVNDLPEQGSNPKLKADAWHLRTTCDENFMEPIGLSCRMNEVQDLLKINFDLQEHYLEPPHLESCTQVVDSSEVHKSPKPNTNDNDPVYRRLETGAAPYFLEANFDVAEKELETVYSEHVSAVDAFTEGGSNVEAIEWNVQDPETVNAELVSQVDAFPVRVNHLNIIEWSERDLQTVNPEHDRVNAFSECGNNVKVIEWKRPESDTITTEHVSEMDTCSESVNSVKLIKWNQQELVTPNTENVSQLDTFSEGGNSVQVIEWSQFDDIDSGTENFVDALNTIESESESDFETEMIKEVPSTGSKEEEEEYAVNGQTSEVTSHLEPDHQHLATAEMGENAVNGQTSKITSHIEPKHQLLATDKIGENAVNDQTSEITSPLEPEHQCLTTSYNVQEEDSDDLERSATSMSSANTWSPDRTWSSHDKSESATGQKRDVPTCLSEEQSLQTIQSATLSNVPQGLDFCVDDPAGIVDPAICEITKFGSDAASDERITCAPHMPQEVSAGSSTSDPLAFWTNGTLFGLAPSKPIVFSMPDSVDSAPTSNGGKVGQCGLDAVQKVDPEGTRAASVNESEHGSSKHLSHQRFEKTCDTSVGHDKINFSDHPVTLDLSNGDAMPLGSKVPRGTNMKNVSSEATGASEDRSSLLSVLSRGLLKNGLRRSGSLGYYETHENSVPLKADERINRCQDDVSHAVPETNLKEKLTSPVNSPPPSPPLGHMKISFQPVDSFDTSRLKLKYPEGIDQYENTLDAFPTFQLVPESIMLQHDIGSDSDDDTFSRSYACMSDESHSHMSDSNSDQWESGDSAESNDHTVYDGLHRISSAESASVSPQLEEADHGSIHVGSGSFSDAHSLSNPLVGLPTLNAKSPFGCQKVEPCVSPALHSSHLQEPTHEPPPLPPMQWRVSRLFDEVMLKQNQVSDSLSQSFVPRLLNSAIAQPAKVDLAKLVSTAHESATIVEPKKVEDQKFVQEQTYHAEKKKETDDKGDFLHQIRTKSFNLKRTGPTRSTYTPTPATSNKITAILQKASAIRKVVGSDEGEDDSWSDT
The following text describes a protein:
Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Also a component of the nuclear pore complex (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Nucleus, nuclear pore complex.
Sequence:
MSKPAILKASDITDELRDEIFGISVQAVEQFQLEREVAAYIKKELDSKHGQTWHVIVGKNFGSYVTHEKGHFIYFYIGPLAFLVFKTA
The following text describes a protein:
Function:
Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity.
Sequence:
MNTKIRYGLSAAVLALIGAGASAPQILDQFLDEKEGNHTMAYRDGSGIWTICRGATVVDGKTVFPNMKLSKEKCDQVNAIERDKALAWVERNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQVIRRDQESALTCWGIEQ
The following text describes a protein:
Function:
Has antibacterial activity.
Subcellular Localization:
Secreted.
Sequence:
MKLPQLLLILLFVVLADSVQPKRCFSNVAGYCRKRCRLVEISEMGCLHGKYCCVNELENKRHKKDTVVEQPMEPRDKSKVQDYMVLPTITYYTITI
The following text describes a protein:
Function:
Neurotoxin certainly responsible for the defensive, persistent, and painful stings of the giant stinging tree. Inhibits inactivation of Nav1.7/SCN9A sodium channel in sensory neurons by directly interacting with TMEM233, a newly described Nav-interacting protein. Has virtually no effect on Nav1.7/SCN9A function in heterologous expression systems and in neurons that do not express TMEM233. Also weakly but significantly affects Nav1.8/SCN10A. Coexpression of TMEM233 with Nav also confers ExTxA sensitivity to Nav1.1-Nav1.6. On the Nav1.7/SCN9A channel, causes a significant hyperpolarizing shift in the voltage dependence of activation. Its effects on Nav currents are irreversible, with no apparent reduction in activity even after repeated wash steps over 30 minutes. Does not show activity on Nav1.9/SCN11A. Does not show insecticidal activities. In vivo, induces nocifensive behavior in mice (licking or biting and shaking or lifting of the affected paw) lasting for approximately 1 hour.
Miscellaneous:
MISCELLANEOUS: The name 'gympietide' is derived from the name in the Gubbi-Gubbi language for the stinging trees (gympie-gympie).
Subcellular Localization:
Secreted.
Domain:
The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.
Sequence:
MRFALVAAITIALLVAGSVADESSEDIDNIVIKTPLDLPRCDSPFCSLFRIGLCGDKCTCVPLPIFGLCVPDV
The following text describes a protein:
Function:
Sugar phosphate/phosphate translocator that transports inorganic phosphate, triose phosphate, 3-phosphoglycerate, xylulose 5-phosphate (Xul-5-P) and to a lesser extent ribulose 5-phosphate. Does not transport ribose 5-phosphate or hexose phosphates. Provides cytosolic Xul-5-P to the chloroplast, where it is used as an intermediate in the plastidic pentose phosphate pathways.
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MISLNLSPSLNPGLLHKTRTCQQPTRLSALLVTNPKPFNHRHPLGLSPIPNLQIRDVSAKPLLSLTNPESSSGFSRKPRSIAAVGSSDSNPDEKSDLGEAEKKEKKAKTLQLGIVFGLWYFQNIVFNIFNKKALNVFPYPWLLASFQLFAGSIWMLVLWSFKLYPCPKISKPFIIALLGPALFHTIGHISACVSFSKVAVSFTHVIKSAEPVFSVIFSSLLGDSYPLAVWLSILPIVMGCSLAAVTEVSFNLGGLSGAMISNVGFVLRNIYSKRSLQSFKEIDGLNLYGCISILSLLYLFPVAIFVEGSHWVPGYHKAIASVGTPSTFYFWVLLSGVFYHLYNQSSYQALDEISPLTFSVGNTMKRVVVIISTVLVFRNPVRPLNALGSAIAIFGTFLYSQATAKKKKIEVGGDKKN
The following text describes a protein:
Function:
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Sequence:
MNCEMVTSPESVNLGDSNRAVSPFCLPDCSENAVAQTRSKTLDNAALDLPYVGNRKKSEQDFFKMLSSRDRDAHSTLRKRSNSLSSFLSTKSTSASENKFHGGLNWLSLKLNLLLRLQGRMNSARTNTSMNPYSCDSNENLSTLSSVNQNFNSRQLLATIVPESIQNGCSLLRITKKKVRQRKVSLDPISGYLMLDKNTGKAYKKLCVDDIKEIRQGRDARNYREQYKISSENEKRWFTIIYCADNKLKAMHMISPTLDAHNQWIMALEGLKTYRLNEFIIGLNLVCHQGEKMIDYSENLNPWEKLEKEQSAQLDLGDVHRMCQMLHLNASMEFLEETFQKADADHSGKLSFEEFQHFVSLLKTRSEIVDIFKEYTSGSDKMSLEQFRHFLSTSQKARLDSDSIRTLYVSFCSNDDSKMGLIEFTSFLLSPHNSPVVPVIQDMSRPLNEYLISSSHNTYLLGKQFGGESSIEGYIRSLQRGCKCIEIDCWDGPNGPVVCHGHTFTSMIKFNDVIDAIRKYAFVVSPYPLFISLEIHCCPDQQRQMVSYMKQAFGDTLVMKPVTANESVLPSPEDLLNKILLKVKCSATPLHQFSTDILKVGITDSSTDTTESSELENSELTGLRKGKRRMKNIIVQELQQLAPYARSLKFRNFSLPESKTYSHIFSFSERTIKKHGKAMVPRLSKHNLRYLCRVYPGPLRVGSTNFNPQVYWRLGVQMVALNWQTYDTGLQINDALFIADPPTGYLLKPPCQRIIGTTVGEEGLPRKIKLTIDVISGQQLRRARELSNSETLSPYVEIQVHSMEESPFRWCSKVVHENGFRPFWGETMVYESIISDDFYSMIRFLVHHRGSNGNDSIFANFTCPIDRLQQGYRHIRLLDMQGENLLFSSLFLKIKKEDI
The following text describes a protein:
Function:
Component of an histone acetyltransferase complex.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MLYLEDYLEMIEHLPQELRDRFTEMREMDLQVQNTTDSIEERIRVLFCNAKKLKTPERDAEYENIRKDYFKVLDDADEKVQQANQMYDLVDRYLRRLDQELHKFKMELEADNRGITEVLEKRSLELDMHNGSHSQKENRHVTSHARVTERDRERDGRRQIGATQMNRQSSTASLPAMEKTWYGETPSASQAIPTTPLAVAAPISATLGHSSSGSSVIAAAASQAIAATQQMQQGRRSASMKASYEALQQFTQSTDVGVLGITPSLALSSSDAREAAANTTILASTATKKQKKRREPVIELPVAANEPMEVVTEETMETEESVEGEWAPDPNEPRYCLCNQVSYGDMVACDNPDCPLEWFHYACVDITAPPKGKWYCPRCATSMKRRGRKQ
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MPAFKQQTIVDFVTAESASATQQQLQAVHNGRGFCEQASVKVLETYLAEQVQNSTVDIDADLALLKLYLVYPATVNAENVAKVLVKGVMALPSTFFTGASTLVPESIREDASVTAVLHTGFLLQSCLFEDFWKEEVTFAKKVPGFLESVRAYILTAISRSHSAISTEVFKAKLNVSDKEVADIVAAEKWTVADNLVQISPNEDNQMQAKKVQENIEFEDVLKVIHTLSR
The following text describes a protein:
Function:
May act as a GTPase-activating protein for Rab family protein(s).
Sequence:
MSLGRLLRRASSKASDLLTLTPGGSGSGSPSVLDGEIIYSKNNVCVHPPEGLQGLGEHHPGYLCLYMEKDEMLGATLILAWVPNSRIQRQDEEALRYITPESSPVRKAPRPRGRRTRSSGASHQPSPTELRPTLTPKDEDILVVAQSVPDRMLASPAPEDEEKLAQGLGVDGAQPASQPACSPSGILSTVSPQDVTEEGREPRPEAGEEDGSLELSAEGVSRDSSFDSDSDTFSSPFCLSPISAALAESRGSVFLESDSSPPSSSDAGLRFPDSNGLLQTPRWDEPQRVCALEQICGVFRVDLGHMRSLRLFFSDEACTSGQLVVASRESQYKVFHFHHGGLDKLSDVFQQWKYCTEMQLKDQQVAPDKTCMQFSIRRPKLPSSETHPEESMYKRLGVSAWLNHLNELGQVEEEYKLRKAIFFGGIDVSIRGEVWPFLLRYYSHESTSEEREALRLQKRKEYSEIQQKRLSMTPEEHRAFWRNVQFTVDKDVVRTDRNNQFFRGEDNPNVESMRRILLNYAVYNPAVGYSQGMSDLVAPILAEVLDESDTFWCFVGLMQNTIFVSSPRDEDMEKQLLYLRELLRLTHVRFYQHLVSLGEDGLQMLFCHRWLLLCFKREFPEAEALRIWEACWAHYQTDYFHLFICVAIVAIYGDDVIEQQLATDQMLLHFGNLAMHMNGELVLRKARSLLYQFRLLPRIPCSLHDLCKLCGSGMWDSGSMPAVECTGHHPGSESCPYGGTVEMPSPKSLREGKKGPKTPQDGFGFRR
The following text describes a protein:
Function:
Probable protein kinase required for meiotic recombination.
Sequence:
MDFLSHAMLSRSESTQILCELSQIDESTMDPQYTEDDVLARLFVFSSSSPQTVLNVKKYEDVSVGRSNTCNYQLLQFTASYKHFRVYSVLIDDDMDPLVYCEDQSSNGTFLNHRLIGKGNSVLLSDGDILDVRHCASFLFQQKYTTDNDFHHEYAGERFNITQRLLGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFEDHEMTILRKLDHPNIIKVNMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQGLKYLHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFVGTPEYTAPEIQRLKGRSQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSPSFADGVKEKQVDFRDPVWKSVSRQAKDLISNLLKTNPPDRFTVKQCLSHPWFARHSSRLTKLYETRILKPLKHSRL
The following text describes a protein:
Function:
Seems to have esterase activity. Prefers ester of fatty acids from 4 to 16 carbon atoms.
Miscellaneous:
MISCELLANEOUS: Present with 35600 molecules/cell in log phase SD medium.
Subcellular Localization:
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP) found only in mother cells.
Sequence:
MSVSKIAFVLSAIASLAVADTSAAETAELQAIIGDINSHLSDYLGLETGNSGFQIPSDVLSVYQQVMTYTDDAYTTLFSELDFDAITKTIVKLPWYTTRLSSEIAAALASVSPASSEAASSSEAASSSKAASSSEATSSAAPSSSAAPSSSAAPSSSAESSSKAVSSSVAPTTSSVSTSTVETASNAGQRVNAGAASFGAVVAGAAALLL
The following text describes a protein:
Function:
The GINS complex plays an essential role in the initiation of DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MADGEEGAGLEDWTDPSIASSAEVSDAGLLQRAWRNEKLSPELLPFQGELVERVKEQILLEEENLAAFVEESCDELTVSLYRMDLDRTLFMLRSYLRARLLKIEKFALHILTVPEIWERLSSQEQDYAQRFADTLQAHFDSSVLNKLPEGYKSMLKQANSSNENDMIVEPPLDSFVFCKCRRPISAFQLDDKGESIVDMENGDLYIFNYKPIKRLLETDRIELF
The following text describes a protein:
Function:
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.
Sequence:
MASLPFGSTASVDSNQLLVETNGSTQTLILNRPKQLNALSSTMIKELLRCFIAYEKDDGVKLLIMKGKGRAFCAGGDAAIEGWKWGANFCRNLYLLNYIIAICIKHQVSLLTGIVMGGGTGVSLHGRFRVATEKTIFAMPETTLGLFPDVGGSYFLSRLPGFYGEYVALAGARLDGAEVLACGLATHFVHSNRLLLLEESLKKVDTSNPFIVLEIINKCFSKRTVEEIISSLEQVASNLPDEWVDATIQSLKNASPTSLKISLRSIREGRTQTVGECLRREYRMVCHWMPPRLEQVHNESVQQYFSTIDDPRWEELNLPTRHSHGRNIKSKL
The following text describes a protein:
Function:
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Note=Localizes to the apical junction complex composed of tight and adherens junctions.
Subcellular Localization:
Cell junction, tight junction.
Sequence:
MSSLSADRKPPLDYGVQIRFIKDLDDAGGGFPDKSRLANGVGGVSNGTSSPSKYGVAVRVQGISGQPYVVLQDGEKGDSYGVQLKTQPQIQSAPPVVSQTSPYNTLLLGQREGARTPQGSYNPTDQPSSPDEDFGSPLRRPPGDGQAGTQGEAEPRTTERFTPSALAPKLDKKDNDAFNEAGLRKVKQNGIGSSLNGTGLNGSFPPPSSAQDEDQAPAIDTKSLAPINKLISRFGGGGGGSGDILNSEAQTRPRLDNRVRSQSADALNKPSEEASSTSPTINPYAPNTSATVPKLNSTKPSSTGSLGRDATSVAKVAAIPNFKPLAFNQSPKLFAPKEAPPAVPKKPVTPDLIKSQTTSIENGNGEDDQTKQAIYNILKEGSIEKEEAIKRKASLIHERFCGVKAPQISVTDSNMKTELEQAFGRNTQLQQQLDKSRRELQENQDQMVELRMDREGAESRLRQQEDQLAQLQEELRRTLENSPQSDSMQLDLLTVQAELSESQLLRQKLEDTLRQRERELTALKGALKDEVASHDKEMEALREQFSQDMDALRHSMETVSQSQLEIEEERQKVNASILAMEEELEGYKEQSEQWKKQFSSANQELLKAQQGKRELEEKLLAVVKQTDETDSNSVMKELQQCRDSLKKAQSELEKQKAETLKKQEELKSATRASEKRETELKAEIDRLINQLKKEKEELSKAIEKTQQPLVSDQTKDPESNLELQEANARLRERIARMTRLHSSVPDSSSSDALEEENRSLKTQLEESRRAASRLGVEKEELNRRLEEREREREALRRGKSDLEEQKRLLDRSLDKINKEMESMMGDSRQSVQVLQSQLEEFRDRSRRELQDAQRLSKDRLVELQRAQALLKTTQEEVSRVKKELLSCTEERDSTQLDKELLSSRLKNMETELQTDRSSQTDRSREIRLLEDKVKTLEIELDEEKSGAELLNERITRCREQVDQLRSELMQERSARHDLEMDKSALERQIKELKSRIADMGTQSRPSAGVTMLENKVQELEDRLRSEEREKNTIQAAQRRLDRKLKDVTATLDQERNQHAEQRDQLSLRVKALKRQLDESEGEVERLEGVRRKVLRELEEQRELQAALQAKVNAMDNELRKIQQSRRSTLGSTLSSDEEDNYSDTKSITSILTDSPLQTTSC
The following text describes a protein:
Function:
Serine protease.
Sequence:
TMELLEDLIEQVRQLPMVNFIEKNSLVHANEFTVAKGAPWGLARISHRDPLSLGSFDQYLYDSNGGTGVTSYVIDTGVNVHHEQFEGRAKWGKTIPQGDEDEDGNGHGTHCAGTIGSNAYGVAKNAEIVAVKVLRSNGSGSMSDVIKGVEFAVKSHQDSVKKGKNSFSTANMSLGGGKSPALDLAVNAAVKAGLHFAVAAGNENQDACNTSPASAENAITVGASTISDARAYFSNYGKCVDIFAPGLNILSTYIGSDAATAYLSGTSMASPHIAGLLTYYLSLQPSSDSEFFIGAEGITPAQLKKNLIAFGTPDVLADIPADTPNILAFNGAGQNLTKFWGH
The following text describes a protein:
Function:
Putative odorant or sperm cell receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MWQRNQTFLADFILEGLFDDSLIHLFLFSLTILVFLIAVSGNTLTILLICADAQLHTPMYFLLSQLSLMDLMHVSTTIPKMATNYLSGKKTISFVGCATQHFLYLSLGGGECLLLVLMSYDRYVAICHPLRYTILMNRKVGLMMAIMSWLGASINSLIHTVILMHFPFCGSRKIHHFYCEFPAVVKLVCGDITVYETIVYISSVILLLFPIFLVSTSYGFILHSVIQMHSAGSKRNAFATCSSHLIVVSFWFGACIFSYMRPRSQRTPLQDKVGSVFYSIITPTLNPLIYTLRNKDIAKAMRRVLGRDILTQRQQLPLP
The following text describes a protein:
Function:
Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
Subcellular Localization:
Golgi apparatus, cis-Golgi network.
Sequence:
MKRRDAAMEAYAAMQASSEATPTPIQNPLSLYTEFFGIRAVKTGDLVAEQQANMQLCDQERSYNHSAAIIALLSQAMAQFKIYKCLRFRKKLAIDMAEEYLKSGDHAKALTLYSLMLPDYRQEKWTTIFTDVLLKTLRCALLSGSVADYIACSVEALSLRHQSDQSERILILENLWQVFQGVPPMPKTQLTPEAQALWTSALANVKSPIQIDLDKVNDVVEMCATFERVQLSNDDLLQLQLIVRVLTDIPLRIRSFHVILADAGNPQNSYKLEALKYFCFPTLTQLRGQKQPDDEQLENPSQEPKNFEKNMRLEPGSYYQLFCSTEAQQFHENTQLRIVRLEAHMGTDQVAALLTCSSNYSRQLFRHHTRSRDLDDNVTINPICYIAPTFHLDTQTNLGHGHDNGLTDDKEMVATKMLVNEYFPVVTTVSNPYNVYLQNVGVHISIPVGLRNSVFLTTDISPGRQKLHSQIQIDVGELSAHGSNTATFYIFSLTEAEIKLAQRLSYTLDVDRGPGGGGSNARVSTAPNSSESTPDHEVKSVIPSVAAISPVQIEYLDETRLRKSREDTLTVRCYGDFKFNARFYTMDRKPLNQVYRGENFLLRANTEVVAVDDVEILDSFFICDHNLVQSNYSFKQKKYTNKYSAGEQLESVIVLRTNATLRDWATARDLDHRGKLEGKAVASKFIRPVPKPSSEEPLAPTPPAGISAYMSKSLVTKIPTTMTIINSNSAVSNALQVANAGVMSNSTQSDDVNVAEEAINTHEGIKTTRLIYNKALEAVQGTGHCRGFIKKIYTLEGNPSAVPIFGVFCIRWRRANCKEENESKFVIRGLDIAEPPLNIYCTIEEKMFVKMPMAFKVVLKNPTTHVLHLIANLSISKTDNFICSGHKQLDISIMAYEEKELVYNLYPLQVGWQELPVLSLEYNTKADPQKKDSQNALLDELVQRALPKRVFVLPPLKQQNK
The following text describes a protein:
Function:
Type II glyoxalase, isozyme of GloB, that hydrolyzes (R)-S-lactoylglutathione to (R)-lactate and glutathione. Plays a minor contribution to methylglyoxal (MG) detoxification in E.coli, compared to GloB. The two isoenzymes have additive effects and ensure maximal MG degradation.
Sequence:
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDDSGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEECQPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGRSDFPRGDHNQLISSIKDKLLPLGDDVIFIPGHGPLSTLGYERLHNPFLQDEMPVW
The following text describes a protein:
Function:
Snake venom phospholipase A2 (PLA2) that has myotoxic activity but no significant neurotoxicity. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Subcellular Localization:
Secreted.
Sequence:
NLYQFGGMIGCANKGTRSWLSYVNYGCYCG
The following text describes a protein:
Function:
DNA helicase that plays a role in DNA damage repair and genome stability (By similarity). Exhibits a magnesium- and ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). Plays a role in restoring regressed replication forks (By similarity). Required to restart stalled replication forks induced by abortive topoisomerase 1 and 2 lesions (By similarity). May play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MASIPALTDELESVSSELHAVDIQIQELTERQHELLQRKSVLTKRIKQCLEDSAAEASGDCDTSPAAWSKEDFPWSGKVKHVLRDVFKLQKFRPLQLETVNATMARKDIFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLQQLGISATMLNSSSSKEHVKCVHTEMMNKNSHLKLIYVTPEKIAKSKMFMSRLEKAYEAGRLTGVAVDEVHCCSQWGHDFRPDYKALGILKRQFPNISLIGLTATATNHVLKDAQKILCVEKCLTFTASFNRPNLYYEVRQKPSSAEDFIENIANLINGRYKGKSGIIYCFSQKDSEQVTISLQKLGVRAGTYHANMEPEDRTKVHTQWSANELQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDWRADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRALIAQHFDEVWNADACNKMCDNCCKDDSFEKKNITEHCQALIKILKQAEGLNEKLTPLKLIDAWMGKGAAKFRVAGVAVPALPREDLEKIIVHALLQQYLKEDYSFTAYATISYLKVGPRASLLSNEGHAVTMQVKRSTQSSVRAASPEACEVDSKGKEKSSAVLC
The following text describes a protein:
Function:
Peptidoglycan polymerase that is essential for cell division.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Sequence:
MTTDRNLFFCASLLIFLGVLMSYSLSTYTTVVLYHYGEFHFFIRQLVSAIIGIVIMWGLSRVDPSKWFSRLGFFLLFVPPLLIIGMFFLPESLSSSAGGAKRWIRLGFFSLAPLEFLKIGFTFFLAWSLSRTFVAKEKANVKEELITFVPYSVVFVALAIGVGVLQNDLGQIVLLGAVLAVLLVFSGGSVHLFGLIISGAFAISVLAIVTSEHRILRLKLWWSNLQNSLFTLLPDRLANALRISDLPESYQVFHAGNAMHNGGLFGQGLGLGQIKLGFLSEVHTDMVLAGIAEEWGFLGLCVCFILFSVLIVLIFRIANRLKEPKYSLFCVGVVLLISFSLVINAFGVGGILPVKGLAVPFLSYGGSSLLANCIAIGLVLXLARYTKG
The following text describes a protein:
Function:
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. It functions as a gamma-toxin target (TOT); disruption of the complex confers resistance to Kluyveromyces lactis toxin zymocin (pGKL1 killer toxin). May also be involved in sensitivity to Pichia inositovora toxin.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGSVQRQDLVLFSDQSVLPAHFFQDSNSHNLFFITHQSCTQPLWMINALVETHVLGSPSSLNESSSSMLPSSTRSHAVLASFIHEQNYFTNSLNKLKIPSNNYNVLDFLSDFIVNNIHNKPRDKILSDVLAKFSAAIQNNPTDTIVIIEQPELLLSLVSGLTCSELNNKFITPLLRQCKVLIIVSNSDIFNIDEYDASVHSSNLQNFYKSSFIKSMINLNLNPLKTGFAKDVTGSLHVCRGGAPIATSNTSLHVVENEYLYLNEKESTKLFYR