lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Cell wall formation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSPVLSESQLRDFKHTLESSKIPFRSEVRLGILSSFKIGGVCPVIVEPEISSQVSEILHIFSKFDIPWKILGGGSNLLISDHPDNFVTLRLSGKFKEFVSLGDGKFKIGAATNTTPTFRQISQLGYTGAEFLSTIPGWTGGAVIQNAGCYGGELFDLIESVEFLRNGEMFVRKPSEIKYGYRFTEFLNQKDSIILGIEILLKEGNLEEIESSLKDKRDRRNSSQPENKKSAGSVFKNPKVFREDGKEIKAWELLDQAGLRGQIKGGAQISPEHCNFIVNLGTATASDVHYLIDLVVDRVYQTSGILLNREIEFFGDIP
The following text describes a protein:
Function:
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MSNCVKSSDQFTYAEWKANQMNVLLGAELDRASAERLTNETKRYIDEMRQASQHSDQRAEFSQERRMEEVRYWQNELNMKLDQIKLAINDLSSIDRRLDKAMDSIKENCHIVHKCLEARKRRKRIYLVYDPAEKQLCKEREIIEGVLALHCKTKSQVNDQLRLLRKLRHDIEKDVLMKLTNFDVEMESSEIRAKKAAIAAYNYDPNCEGAELCPCKLEGHCCQKTKKPGGLSSISDWLTQVKSVHTEAEKQRQNAANLTSIADSSLKQTKDDLQNIKVATDDAFRERIYELRDHKAKMEDHLQKVVKQIQEMETTSQSLINEINIYTKKLTFEQSKIQPLQNCPQNLLDSEEVLVTNYCTNKGNVEKLKDNLACVQCSLKSLQCRKVEVESDLKLCTEALTIDDYECLPMRQSIKYFLY
The following text describes a protein:
Function:
Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. May act by regulating the catalytic subunit PIGA.
Miscellaneous:
MISCELLANEOUS: PREY is derived from the same bicistronic transcript that encodes these 2 different proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MFLSLPMLTVLIPLVSLAGLFYSASVEDDFPQGCTSTTSLCFYSLLLPITIPVYVFFHLWTWMGIKLFRHN
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase.
Subcellular Localization:
Endomembrane system. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Domain:
The RING-type zinc finger domain is responsible for E3 ligase activity.
Sequence:
MEMEQYFEEASIQINSFGENKSSLENWKSVLDAMAETHCDASGLFDCNICLETVKDPVVTLCGHLFCWPCIYKWIHYQDSSLEKKARRLPQCPVCKAEVSDATLVPLYGKGETQDPFESKNPQLGIVVPRRPQGPACFESPRPTSHPTSHTVGPQFREGNSDSADQSNVYYAEMTGVFGEVVYARMSGAITNLYAYPNSYPLVWSMLVAIGRPLLALVSVVGVNKNFVITSLCGLLLHS
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase.
Subcellular Localization:
Endomembrane system. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Domain:
The RING-type zinc finger domain is responsible for E3 ligase activity.
Sequence:
MEIENQEDDLATLGDSGGEFDCNICLDQVRDPVVTLCGHLFCWPCIYKWTHCTNNTRQRVDQYDKKESSKCPVCKSEVSDATLVPIYGRGQKVPQSGSNVPNRPSGPVYDLRRGGQRVGESESQRYMYRMPDPVVGVVCEMVYRRLFGESSSNVTPYRGDRYTSLRLRRRTMQADESLSRIYLFLLCFMVMCLLLF
The following text describes a protein:
Function:
Potassium transporter that mediates K(+) influx, as well as Cl(-) efflux as a secondary function. TRK1 is the major K(+) uptake transporter that regulates membrane potential and intracellular pH. The TRK1-mediated Cl(-) efflux should serve as a Cl(-) detoxification route and may play a role in sustaining C.albicans on mammalian epithelial surfaces, or in physiological saline solutions such as saliva; Mediates candidacidal activities of cysteine-free peptides, but not of defensins. The hallmark of salivary gland-secreted histatin-5 (Hst 5) killing of C.albicans is the rapid efflux of cellular ATP and other small nucleotides and ions from the cell as well as concurrent intracellular uptake of propidium iodide (PI). TRK1 is the channel for Hst 5-induced killing and histatin-5 may directly or indirectly alter TRK1 function, allowing the efflux of larger anions, including ATP, and the influx of small cationic dyes, such as PI.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLYRVSGFYKRHTRNFTNIDYGYYIRNFIHHIASKIYPYAKVVLPNFRAAHYFYILTLVILGSILVYPVKTCAYIDVLFFTAGASTQAGLNTVNVNDLSLYQQIVLYLLATLATPIFIHGSLLFVRLYYFERHFDNIKERSLMDYRMRKSATLARLGSAPTMSSTRLNTFNNQVLGFQEREAEKGSSSSPQSSSSQTSQPVSTAYNDQGGNDIEHHSEPSDSDDDESGNGPVTFQEKIHFEEPQRPRSQRRHSRTDSGIKFSALPHPRRRKSIDPEDMYRSINMLQEHKKNQEAKSKGIQFLNIGSPVRRKSRSSNIEAFPEEDTNPSRGDEITPATNSVGTGNNDEDEDDILIIKPPIEIENSDEANPIFTKKKKLASQIQFKETPGKAKKWITTKTRKHYNPWTSKLKKTLSNSSKKGSLSVVPTDTEDDSEDEEYASIDSETSDISDNEHAADNAEGSDVDSVGSYEEDEDEDEHNSDDDDDGEGERRLGNGASLTKAQSHLVLPSKDETGGKKYTKRSNTLDTPQQNTSDGRKIRKKAPKRKTPRTQRNASFNQHSNVSIGDGSIENVDTNDSYQRLSRTMSGNYLSWTPTVGRNSTFIKLTDEQKEELGGIEYRAVKLLIKIIVVYYVGFNIIPGVMLSIWIYCMPHYKNLMISSSISPAWWAFFTSQSSFNDLGLTLTSNSMMSFNQNAFVQILCSFLIVIGNTGFPILLRFIIWVMFKTARPLSLYKESLGFLLDHPRRCFTLLFPSVPTWWLFFILVVLNGFDLVIFCILDLHDDTFKGVDMGYRVLNGLFQAFCTRTVGFSVMDLSQLHAATQVSYLIMMYISVLPIAISVRRTNVYEEQSLGVYAKENAEGVDESAPSNYVGSHLRNQLSYDLWYICLGLFIICIAEGKRLKEQDLRFSIFAVLFEIVSAYGTVGMSMGYPGVDCSLSGEFNVISKLVIIAMMIRGRHRGLPYTIDRAIMLPNAAMKRHDRLQEEHAINRHNTMERTTTLGRVATFGNGPIDGGNNLLTRAITNIEHRLRNRRDGRSESSTVSEDPRYVVRTVSEV
The following text describes a protein:
Function:
Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity).
Subcellular Localization:
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Sequence:
MKNNIKVILIGDEQVGKSTIINSFISESFSEITQKTLPEVTIPAEFNNEICSTRIIDTFDDGKNLKNQMNMEIRTADAIVIVYSVDRFDTFMSIRMKWIPLINQLRGSNKSPIIIVGNKLDLVDDKHENNKVQIEETIQYFRSTYSNTIQWLECSAKTMENLPELLYASQTSVFFPERILYNREENKMTEGCERALKRIFKLCDHDNDGSLSEEEINYFQTKCGHETMTSEEIQNIQQFVLSKIPDGVNSNGFTEKGFLYMNLLFLLRGPCQHTWTSLRSFNYDDDLVLLESYVHPTLQVPPNHNTILSSMGNEFFKSLFEKYDSDSDGVLSSFDLVSLFSTTPKIPWEIGFEKHFNTDKDSNLTLSGFLSLWNLQTYENYKVTLEYLAYFGSQTENNNIDMISILNSRELDIKSNQFTRNIVNCYVFGAEAVGKTTFLNTFIGKSFSTLYNATNGNDNFKVCGHLLKNKYLILSEYVGEKIPTAELKSKCDLVCLLYDCNSEQSFKFIENIYNQLKQQQLNIPIVFIRTKNNNNNNNNNNNNNNNNNNNNLNNNNNNINNNNNNNNNNTTTTNANVSTSKIIDSFFKSHKNYSPKDFSISRSNSIYHEMMETIVNSSFNDNSNGSNGSNNSNILTYLVIAAGVAGVGLLLSKYLAKK
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MDQQPPVQPQQRPPPSLTNPRFTLELEFVSSLANPYYLSHLAVTYPNLLGISKSSDDSNTSTEGPDPEAQAFAAYLAYLYSYWKTPEYAQFLTHPGATLRALRLLQEESFRRDIIRPQVIEALAGNGLENVQGGQNVEAGDTGHNEGDQGTQQDKENIALKT
The following text describes a protein:
Function:
Serine/threonine-protein kinase receptor which binds TGF-beta-like ligands dbl-1 and perhaps daf-7. Upon ligand binding, probably activates a TGF-beta-like signaling pathway.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MNITFIFILIFGFFNTQKCSKDYDHFDDEDLALSIPKNAIGVPKEFRQQVLKEMKLRNRPNDILKNRCYCNYDQSICGNNMTCVKQDGAACYHAVEEVYNKAEKRMETLHKWGCATLERGSGASHLTCNSWRAAHHSPKSIGCCYEGNYCNKNLIPPAYVHHHKEKALQEKTDNPEDYDSPLENMTRGGKMFIMVFATVMSVFAVIGCIYLCITRAEEKSKARARAKTVSLKTESTYMESKSMLEDSGSGSGQAALIQRTVRQDLTIIKTIGQGRYGEVRKALYRGSYVAVKTFYTTDEDSWKNERDVYQTNMINHENILQFVAADIWSEEDSMTKMLLITDYHELGSLSDYLCREETLTTDEALRLIHSCICGIEHLHAAVHGTGSFRKPEIAHRDIKSKNIIVKRPNVCCIADLGLALRYQNDKILPEKFNVQVGTKRYMAPELISNKLNPKDFSQFKMADIYSMALVMWEVAIRVEVNTCEEVLTVDETSPDHSASSGIGESVSSSGNISRMHLQKTNVEGHSTSLKAKQHVPPFDGIVHNDPNFDEMNDVICVRRIRPPPDLAWKNVPALNELSKLMEDSWHSIPHFRHSALKLKKEMAELIKNPDRQNQSQRKVEFQQQDSGLVESATNQS
The following text describes a protein:
Function:
Involved in ribosomal large subunit assembly.
Subcellular Localization:
Nucleus.
Sequence:
MTELKQQHTFELDVGNLLVTDRSDVDIEKFKSDSWKYIGEIAKEASKTLIDNIYAREDVSDHSDPSLGKVVILDEPEMKFPREKPLPASKEPTKWELFAKRKGIKKTKKSGKVWNQETHSWVPRFGMGSAKQIKKKTEGWIVEDKVGLSDNPFEGIDKKKLKEETKPSRSGKKIKKSLSKIKLTPGTIGKDGYMNKKDAQKLLKIAQRSSASMGNFSKNLTGEKIVAKKRKLKQSDFVKGGDKAKNMRVLDRLTKKKN
The following text describes a protein:
Function:
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Subcellular Localization:
Nucleus.
Sequence:
MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAQNEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAEAPTGKRVAEDDEDDDVETKKQKKTDEDD
The following text describes a protein:
Function:
Involved in cell division and chromosome segregation.
Sequence:
MTFSTQIKAELVQNKLIDKHWNVFLAGFFQNNLKLLYNRNWSFKVQSEALKEQFVQNLKFDFKTKASKKYFLFEFNADINVINTLLKLDVTTSELVVKQVYLIAAFLSGGSVSDLINSNNFHLQISSNNEFQIQQLLKLFSFFKKTVKQNQLVVYLKSYEKICNFLKLIQAFDGYLAFENKQLEKSFTLNQLRKSNLEVANLMKTIRSNNQTNQLQLKSFIKSSSFAKRPLNFQRYCLIKSDHPDWSLEQIANFFFTKYNIKISRSGIQHFSVNLKKLCQ
The following text describes a protein:
Function:
Serine/threonine-protein kinase involved in the regulation of auxin signaling. Plays a minor role in the regulation of cellular auxin efflux and cotyledon organogenesis.
Sequence:
MANSSIFYKDNESDYESSTVGPDSSRRTSWLSSSFTASPSCSSISHLSNHGLNSYNQSKPHKANQVAWEAMARLRRCCGRAVGLEHFRLLKRLGSGDIGSVYLCQIRGSPETAFYAMKVVDKEAVAVKKKLGRAEMEKKILGMLDHPFCPTLYAAFEASHYSFLVMEYCPGGDLYAVRLRQPSKRFTISSTRFYAAETLVALEYLHMMGIVYRDLKPENVLIREDGHVMLSDFDLSFKCDVVPQFLSDNDRDRGHQEDDDDISIRRKCSTPSCTTTPLNPVISCFSPTSSRRRKKNVVTTTIHENAAGTSDSVKSNDVSRTFSRSPSSCSRVSNGLRDISGGCPSIFAEPINARSKSFVGTHEYLAPEVISGQGHGSAVDWWTYGIFLYEMIFGRTPFKGDNNEKTLVNILKAPLTFPKVIVNSPKEYEDMVNAQDLIIKLLVKNPKKRLGSLKGSIEIKRHEFFEGVNWALIRSIKPPWVPKEETSHKTKGDNRSVNYYLPPRFMMSRKERNEPYHVSNYFDYF
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MVKSKSDLVNSKKTTQNINKSTPTVKIVNPFDRKINKVKHEVLNRKVRGVATDIGQSRYNAIEKRKKTLLVEMNQQKKTNKFIDSRYGENDPSMSEEDKMLARFQKEKMRNKNLYSLDDNEESHELTHLGQSLGQSLGDGVVAQDDYVASDDEVDEDNEFLSERQRFGGGEDEQNKRETHKSSKEVYQEIIEKSKQGKAERAREKLLKEAFSRELDEEFNLIRGDLVLSNQVKNSPVEDDAFLKFQAESRAAEQKEKDSGSSSKKEKHDDFDELMVQLQGETRARASDRTKTKEEIMKEEMERLQQKEKERLERASGDYVELEKDAQDSDKNLPKRVKDRLKEKDNKPKMLSADSLDDGNEVLNVNGIDTVFYNPQIDSDEEKQSGSDDDDEDEDDDEEDEDEENEEDGEEQDDEEENDSDLEDDEVISGEIEEDEEELEQERLKNKKSKKSEEEPVETIPYTFDVPSSIEELNEWLENRNDEEKQTILSRIRVCNHISIKPQNKEKMKAYLPILYQRFINTATASDEHSVDLKELDSLSTYIFEVSQDVPDISGSSAKELVNNTYKRICKKLEIQSKLNYWPNQSELLLIKLLGNVFPTSDFQHPVCTPAVESLNFYLSHCPIKNINDIASSLFTSNLLFFYLSSSKRYSPEISSLLISLLSTFVNQNQTVNSDQQNKTNNKKLTKQQQQQEKELQSQKSKQNQWATINSNILVPTILLPENYLKLSPSTKSEPISSIEPKKLEFSTLSKSNIQFTNSLKINLLNYLVSFIEKYIKFYSETQFSESLPSLFNTLLSIVNKLDTKLYHKELASKIESLRNTIEKINNEIINNRKPLILLTGKPQQLRQFNPRFNTTSFFNKDPDAERAEAKKKKALIKKETKGAIREITKDNQFIQAEKFKKAQVERAENDKKRKHIMSELQKEQQEGKAYKKMKDRLDGRI
The following text describes a protein:
Function:
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MAAADVRDMLDLPAEGQPRPHKKQKVVEKRPEGITRELFALLGERAPPIAINENRYKGRPKWQTKARVRPCARSDDLVLRHWQREPESTNIPAIEDTRAEGETKEQGEHKTADREYPFAKYNIKLKFSNRYTTDEYNRHLRSEDWSREETDYLMDLVEEYDLRWVVIADRYDFQPQRVDNTEETSSALVPSKQFRTMEQMKARYYFVAASMLALEHPPSEMSEAEFDLHERMMKFDPERERHRKELAALQLNRTADEVREETVLLEELKRITANEQEFVTERRELYSRLDVPISVSNATNYHNSQGLSHLLQTLLQADKSKKRRSILGPDGIAPTSGGQTPTIPNAPGSARDSSRADTPNGGTTQSTTTKKAAAAANREAAQQAIRTLTPAEEARYGVQHHDRLAPGVQFRSDRAQKLTQAKSHVQTQKLASALAELEVPLRLFMPTERVVKEFEKLIHSVNLLLDARKVAEKVESEIRVLEAAKEERERKAKELREKDKPEVKSEQQDNDVPIPPAPAPVAAGDASQTGQPAKTNEGQAELNGSSTTNNVADSEPSTQEQEGVSHKRSASVLSNGSDKSSKRQKK
The following text describes a protein:
Function:
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
Sequence:
MECPINPAELQKLKVFINLCQMTPQLLNLPQLEFLKSFIESLGGKVPEGQPDLAGMMGGQKAPTGDGGAAPGKPASAEPEPKPSTAAAPESDPESDLELDNEGCVEPDTEPDQPMGVADKEPTEEEFDQANDLRAQAAAAYSEQKYDEAVKLFTEAIQLNPKSALYYAKRGQAYLKLQKPNACIRDCNRALEINPDSATAYKFRGRANRLLGRWEEAAKDLRQACKLDFDEEADEWLKEVTPNAKKIEQHKQKQERRRQEREFRERQERVRMAQEANRKAAEEGAGADGAPNAGGMPFGGGGGFGTEELLNAFRDPEMSAAMSDIFSNPANISKYQNNPKIMSVLMKLYSQGQGGGFPGFPGFPGGAGGFPGGAGGFPNFGGSDGGAGAGPGAGAGAGAGAGAGAGSGGARVDDLD
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Cytoplasm.
Sequence:
MAIMHKIGCAGSEVETDRVLEKDQANNGHFVDSDCCFQETGSTGTANSICTLNDSEDDNSSLNSVDNNECTNLDCGGKKHKNLSPNPSFHVNINAAEFIPKSHNGYAPKSMNPPPEQLDSPCYPHFDQDSSSVIYPSPPSTYYPNMYVSANTFIPMPYAHYTDNMYHAKPVNRPNFLPREGTPPPFAQQPAEQFSPFNSEYESLLDFRALILGNLPVDYKISELLSLIHSGPLEKIQSNPGKRRIIITFLDSADAFFFYERYHPRGFIFHGRPLKLTFARPSPLPESIQNFCSNTAASRNVFIGNLPSSYHEKEIEEAFGKFGKIEHIKILSKKNIAFVHFLNIRDAIKVVRTLSCDPDYHSWRIFFGSDRCANHPPSFDERSCFTSKQNPDTTSDRCRQQESKDNGNRTVFLGNLHTKTKGHEICDLIRHGGLQDFHYIPEKHICFVTFITYSAANAFHDYLAEEEVLLHGRRIKVGWGKESGPLPRVLEDSILMGASRNVYFSHISDSLTTEELELILRQYGEIESIKYLKNRSSGFVAYTNISNAMKAVNGLPIHPLFKKSKIRYAPDRCEQELQKSKSNSPIQQNVPLQQFITPPFSYPVAYCPAIPPGSDPILNFGIQYQPFIPFTAVPSFPFNCNVPNYPQTSDHEND
The following text describes a protein:
Function:
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Sequence:
MYVTKKDGRLELLDKNKILQRLQSLSTNLSTPYLSLPTLATSILHGTYPNLPTREIDTLASETAASMSTQHPDYGRLAARICASANHKSTPDSFSKAMLLLNEEGGGFVNNEIADLVKRRGKEIDDRIKHERDFEMTYFGYKTLERSYLLKLNEDTIVERIQYLWMRVALGIHCYANLQAAFETYDLMSRGYFTHASPTLFHAGTTHPQLSSCFLVQMSDDSINGIYDTLKRCAVISKAAGGIGLCVHKIRARGTFIKGTRGVSNGLVPMLRVFDVTSHYVDQGGGKRPGAFAIYLEPWHADIFDVLNLKKNHGKEEQRARNLFYGLWVPDLFMKRVEEDGVWSLMCPHRCPGLSECHGEKFEELYAKYESDGRYTRQVRARELWAAILEAQIETGTPYLLYKDAANKKSNQQNLGTIQCSNLCTEIIQYTNEEEVAVCNLASICLPKFVVSDRGNFGSTEGSGAYFDHEQLHKVAKIVTKNLDKVIDVNQYPIEGAKKSNRSHRPVGIGVSGLADTFLRLGLPFASEEAKTLNEAIFETIYHASLEASNEIAREKGSYETFAGSPASEGKLQFNLWGVDDVETPSHRKDQSALAFQKYSTQVNGGGYDWETLRQNIIEGGLRNSLLVAPMPTASTSQILGVNECFEPFASNLYVRRVKAGEFIIVNPHLIQDLTDLGLWNQSVRNQLMRDGGSVAKIECVPDRLKGLYKTVWEMKMKDVIDMAADRGKFIDQSQSLNLFIADPTVDKLTAMHFYAWKKGLKTGIYYLRTRPAVNAIQYTVEKDALPEVDASPQQNIPTLDDSETCLSCSA
The following text describes a protein:
Function:
During meiotic DNA recombination, binds to and activates DNA double-strand break (DSB) hotspot sites.
Subcellular Localization:
Cytoplasm. Nucleus. Chromosome. Note=Localizes to chromosomal double-strand break (DSB) hotspot sites during the meiotic cell cycle.
Sequence:
MKKRSETLGSDQSSSEIIEHVLEELNLKNIERRVKKYDQIESEYKTNIENEKKAFIKDVSQVQQKIKEFEIQKANQIKQLNEEKLSIEARKQQLEIEIRNQLLQYAEKLRIVVKTPMNQPTNTEV
The following text describes a protein:
Function:
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (By similarity). Acts in sensory neurons including AWC to regulate starvation-induced thermotaxis plasticity and salt learning behavior.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Note=In neurons, localizes to the sensory endings and to cytoplasmic punctate structures.
Sequence:
MSSGAPSGSSMSSTPGSPPPRAGGPNSVSFKDLCCLFCCPPFPSSIVSKLAFMPPEPSYTITEDNKLVLIEGRAAWPHQEVDMANCVEMRITRTRRRNRVACTMIRPLPNSHFTLLFSHGNAVDLGQMTSFLYGLGFHLNCNVFSYDYSGYGCSTGKPSEKNLYADITAAFELLKSEFGVPKEKIILYGQSIGTVPSVDLASREDLAALVLHSPLMSGMRVAFPGTTTTWCCDAFPSIEKVPRVKCPTLVIHGTDDEVIDFSHGVSIYERCPTSVEPLWVPGAGHNDVELHAAYLERLRSFIDMEASAIRVTAPITNATSTNSRTISNGTSS
The following text describes a protein:
Function:
Specifically binds to the promoter of the spliced leader (SL) RNA gene and thus is essential for SLRNA transcription.
Subcellular Localization:
Nucleus.
Sequence:
MSTTTDFVGRNCPHCSAVDSLQTDDVMGEVACTACALVVAMGLEENVFTRYNENATYEDVDHHRERNANPTAATSAAGSLSAADPHMSSTSSKVVLHPTMLNCMRGLHKKAVLPEPVLDRGIELARAFVGGRRARGQRVERQPDVAAACLMIAAEEAQQPLPLAEVRCLDSSLGDVELRRADIVRELHLEDSERRLRDTFADNLLVKYILKLGLQVSLYLPHCKRLLTALGRVEALAGLTVADRVTTALLLARTAQTLSWEQGTHISKGKECDLGMEAIYANFSSKAHLEVTKVNKIMHLAVDVLPLIQAAFQDCGEPTAGKRKVDKNSEPEASGGTKRVKREET
The following text describes a protein:
Function:
2-oxoglutarate-Fe(II) type oxidoreductase; part of the gene cluster that mediates the biosynthesis of endocrocin, a simple anthraquinone interesting for many biotechnological applications. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) encA. The atrochrysone carboxyl ACP thioesterase encB then breaks the thioester bond and releases the atrochrysone carboxylic acid from encA. The atrochrysone carboxylic acid is then converted to endocrocin anthrone which is further oxidized into endocrocin by encC. The exact function of encD has not been identified yet, but it negatively regulates endocrocin production, likely through the modification of endocrocin itself.
Sequence:
MTKPQPPPILDFSVFYGHDSQAKAQLVQRVRECCLNNGFFQITGHKVSPELQRRTFDCAKRFFDLPLIEKKKIERSPDAFNRGYEAFQSHMSQPGSAPDRKEGLFLGPDLAEDHPYCVQKKLNCGPNRWPQGLDDLEEFKLVSMEYYAALFQLAKDVVAVLALTMDYEETFFDPLTEGAIATLRYLHYPPQPVGDAEAGLGTGAHRDYSCITLLLQDGTGGLQVLDEPTGQWLDVKPVPGAYIVNLANVFARMTNGHYKSALHRVVNKSGMERYSIPFFFTGNPDYVCECLSRFRKEGEPVRHPPATVHEVVAEAVRGTVERANRYNAERQGIHAAQ
The following text describes a protein:
Function:
A putative protease, its function overlaps that of the related putative proteases HhoB and HtrA.
Subcellular Localization:
Periplasm.
Sequence:
MKYPTWLRRIGGYLLAFAVGTAFGIANLPHAVAAADDLPPAPVITAQASVPLTSESFVAAAVSRSGPAVVRIDTETVVTRRTDPILDDPFFQEFFGRSFPVPPRERRIAGQGSGFIIDNSGIILTNAHVVDGASKVVVTLRDGRTFDGQVRGTDEVTDLAVVKIEPQGSALPVAPLGTSSNLQVGDWAIAVGNPVGLDNTVTLGIISTLGRSAAQAGIPDKRVEFIQTDAAINPGNSGGPLLNARGEVIGINTAIRADATGIGFAIPIDQAKAIQNTLAAGGTVPHPYIGVQMMNITVDQAQQNNRNPNSPFIIPEVDGILVMRVLPGTPAERAGIRRGDVIVAVDGTPISDGARLQRIVEQAGLNKALKLDLLRGDRRLSLTVQTAQLRNPTS
The following text describes a protein:
Function:
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MNRKVTAIALAAIIWATAAQGFLMFKQGRCLCIGPGMKAVKMAEIEKASVIYPSNGCDKVEVIVTMKAHKRQRCLDPRSKQARLIMQAIEKKNFLRRQNM
The following text describes a protein:
Function:
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Sequence:
MPSLFHGVYQALYDYEARTEDELTFSENSLLYLLEKSSTDEWLKAKKAGPAGTNEIGLVPLTYIEPAPAKRQAYALYDYDKQTEEELTFKEGDALTVYDDSDSEWLLVCRGGDEYGFVPANYTGDAPPSAAPAPVAAIPTPVAAIPTPAGQPTTPITKDSPLPPLPKDAFPPPPQAYRPPASTTHASTEPVYANGRDEESPPPMPARPGGSGNGSGRPSSGAGDSRSRGSSVSRSRNASSANDKPSSSSANFFTWPVQEVDGRKKRKATLAIGNGMIMFSPERSSGQPQQWPVKDLVNYNSEKKHVFLDFKHPTVSFDLHLGSKDTADEVIYALGELAGAYNSSGLTEVMMAANSAGQKLGKVLYKFDAQGRDEVSVEEGENVFIIDDTKSRDWWMVKNSSGVAGVVPSSYIEIAPSEKTLKKVVDQQRKASGSSRDKSRDRSRDDRSRDRADKRSSRSSRDAPKSKPDPRKVRTWTDRSGAFKVDAALLGCVDGKIHLHKVNGVKIAVACSKMAIEDLEYVEDVTGVDLEEDKPLSRDRGGSSRDRRRSTSRSDRRKSSSGAASSANAPKPTPESDYDWFGFFLDCGVDVHACQRYATSFTRDQMDESILPEVTPSTLRSLGLKEGDILRVTKKLDEKYGRSGTGTSASTPVGGNPSGGLFSDTTGALKNNTSKTLTKADDTDPWSSLDKQQAPPQQQAPPVQQQPPVQQQPIQAQPTAPIQQQPIQAQPTAPIQPVRTGSINDLMNIKPLQPTPTSSNLQTQATGGIMQPIQQQYTQQPMSQSTSALPQQSMNTGILPQTTGPLQQSLTGSAPVQNPFLTGGPNTLLSQQTGGLVGVPTGGLVGVPTGGLQGVPTGYTAQNVLGMNQPANTGGYSMNAITNALAGASLNKQQQQQQPMVQQLTGGSMFGQQPMQQQLTGSSIFQQQPMQQQFTQQQPMQQQFTQQQPMSQQLTGGSIFNSQPQQPFQQQPMQPQQTSFQQQQPFSTGASASPFGSQPTTPFGQPQQSAGLSYFNNIQPLQQQQAFGQQMQPQQTFQPQQPFQQPFQQPFQQQQQQPFQQQQQQPFQQQQQPFGGLQSQPTGFGFGNSSSPFGGMQSQQTGAPSTSFGQQPLQPTATGRQRANLASATPNNPFGF
The following text describes a protein:
Function:
Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis.
Subcellular Localization:
Cytoplasm. Early endosome. Endosome. Recycling endosome. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Sequence:
MSGSSKQPHAKGKTLIIEDDCEAEALDEANPFSFKEFVKSQTFPGFVSSNSKRAFSKDSNQSTTQFRGPSECPDGNLEFQETYFRDPTLYDDLQEDEDDDWSGSYHPSVIENTHGPKVPSPAGTDGDESYGYGASDMSGDGLITGWQQAVLPSPPAGLHGKTQHRPDSTSDSEEGLRLLQINCEELQEENLHLKSKICKLKELNDSQNEKVRQLERKLEERILEEQKEAQDLESMVQQVEKNLQMMTKRAAKAEGNVTKLKQEMALLQIELTTYKAENEALRRGETAGMNAVKQNSNLALENLQKVVSGAQSSIKQLVAGAEALTLVAELLRSIDKIAEIHNDGVP
The following text describes a protein:
Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Sequence:
MDKNELVQKAKLAEQAERYDDMAACMKRVTEEGGELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQEMSREYREKIEAELREICNDVLNLLDKFLIANATQPESKVFYLKMKGDYYRYLAEVAAGDAKSDIVGQSQKAYQDAFDISKTEMQPTHPIRLGLALNFSVFYYEILNCPDKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTHGDEAEQGEGGEN
The following text describes a protein:
Function:
Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSTTVDIIDPVPFDKGIGDVRSDVSPINWMVAGHVSMNPNVLGFRASGCGGLEEMATHLNDDEAMYALVRLQEKVDLSSTVKFVYIHWVGESVPFTKKGRYGVVHGSIKEKIGQYHCIVETSSKADLTEEAIMKILMETSGTKSMVMEKSEAATRMDRGFTSSSNIIKTGKQARGVQVPDAIAMIIGSSVMDAIAEVRSDEHPINWCVAVYEGNNPKLPIILGGKGSGGLPEMASCMKEDYVSYALLRVTDIVDQISTVKFVFIQWIGESVKPMTKGKISTHKPTMQKVFGVSFHLVLWPFYCK
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane. Mitochondrion membrane.
Sequence:
MFKVIRRLVGPASLSLLTFRGYAAPKEDSAPGSYKRMSELSLYSVPEGQSKYVEKPRTLLEENISQLRHLCEPYTSLYQEMYSHTKPKVEYLVQWGVSNYNHLKNAPPGFLPRLGVIGFVGLLFAKGSKLKKLVYPPFFMGLGASVSNPEKVITIAQISGEKLYDWGLRGYIAVGDLWKQNIQKPGSVKNPLGSK
The following text describes a protein:
Function:
High-affinity transport of uridine.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPVSDSGFDNSSKTMKDDTIPTEDYEEITKESEMGDATKITSKIDANVIEKKDTDSENNITIAQDDEKVSWLQRVVEFFEVKNDSTDLADHKPENPIRTFKDLQESLRSTYLYNTDLRPVEAKRRTWTWKQYIFFWISGSFNVNTWQISATGLQLGLNWWQTWICIWVGYTFVAFFLILGSKVGNNYHISFPISSRVSFGIYFSIWIVINRVVMACVWNSTLAYIGSQCVQLMLKAIFGTNLNTRIKDTIKNPNLTNFEFMCFMVFWVACLPFLWFPPDKLRHIFALKSAITPFAAFGFLIWTLCKAKGHLALGSLNDNGGAISKTVLAWSVIRAIMSALDNFSTLILNAPDFTRFGKTYKSSVYSQLIALPVCYAIISLIGILSVSAAYTLYGVNYWSPLDILNRYLDNYTSGNRAGVFLISFIFAFDQLGANLSGNSIPAGTDLTALLPKFINIRRGSYICALISLAICPWDLLSSSSKFTTALAAYAVFLSAIAGVISADYFIVRKGYVNIFHCYTDKPGSYYMYNKYGTNWRAVVAYIFGIAPNFAGFLGSVGVSVPIGAMKVYYLNYFVGYLLAALSYCILVYFYPIKGIPGDAKITDRKWLEEWVEVEEFGTEREAFEEYGGVSTGYEKIRYI