lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Part of the ABC transporter complex CydDC that exports the reduced low-molecular-weight thiols cysteine and glutathione to the periplasm. Export of these thiol-containing redox-active molecules may be crucial for redox homeostasis in the periplasm, permitting correct assembly of various respiratory complexes and formation of correct disulfide bonds in periplasmic and secreted proteins. CydC contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Required for the assembly of functional cytochrome bd-type quinol oxidases and periplasmic c-type cytochromes.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Domain:
In CydC the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
Sequence:
MRTLLPFIRLFKFAKFPLILGLVLMILGLGSSMGLLTVSGWFLAATAIAGLGTLFNFFYPSASVRGLAIGRTVMRYFEKIVTHDATFRILSKLRVQVFEKIIPLSPAVLNRYRNSDLLNRLVSDVDTLDSLYLRLLAPFFTAVFVIIAMMIGLSFINIPLALGLGLFLLILLMIIPTVFYRLGQQFGERLIQARATYRTQFLEFIQAQAELLLFNAEDKLKEKMLVTEKTWQEDQAKEAKLSGFSTALVLFLNGLLISGMLWFASNADFGTDEYHTAYIALFTFAALAAFEIIMPLGAAFLHIGQVIAAAERVTEIIEQKPLVEFNGNEEFETKVRLISAKNLNFSYPEQETLVLKNLTLDLEQGKKIAILGKTGSGKSSLLQLLVRNYDANQGELLLAEKPISAYSEETLRHQICFLTQRVHVFSDTLRQNLQFASADKISDEQMIEMLHQVGLSKLLEQEGKGLNLWLGDGGRPLSGGEQRRLGLARILLNNASILLLDEPTEGLDRETERQILRLILQHAENKTLIIVTHRLSSIEQFDKICVIDNGRLIEEGDYNSLITKENGFFKRLIERV
The following text describes a protein:
Function:
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
Sequence:
MATSATSPHAPGFPAEGRCGYYVEKKKRFCRMVVAAGKRFCGEHAGAAEEEDARKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFYIQDINAGLRDATEIPEQLVPISSLSEEQLEKLIKKLRKASEGLNSTLKDHIMSHPALHDALNDPKNGDSATKHLKQQASILGNIENLKLLGPRRCFVEFGAGKGKLSHWVDIALKDAEKVHFILVEKVTTRFKVDGKHRKKNSVFERLQIDIQHLCLNKIPVLREEKLPVVGIGKHLCGVATDLALRCLVETYAASFEERNEEPLAKRIKNDKTEKEIYTLAKEGNEKNVPEKWNPVAGIVIALCCHHRCDWRHYVGKEYFRALGLGAVEFHYFQRMSSWATCGMRKTSLETSNSTTKRQDNQNDDSEEHDDGGYRITDDGADCLPGLLSVEDKKKIGHLCKLLIDQGRIQYLQQKGFSPALQYYTDPLVSLENVLLTALPNHSSSPETTA
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Miscellaneous:
MISCELLANEOUS: Present with 2600 molecules/cell in log phase SD medium.
Sequence:
MTAPHRSTIHILGLGAMGTVLAVDLLRFTNALVVPLFRSQERLAQFQKTNGNNISIRKLYLEGSPIFSYPVEKCECPETFSKKPIDNLVVTTKTYQTKEALAPYLPYINKNTNLILIQNGLGVLELLREEIFTDSKNRPHLFQGVISHGVYQDKAGVFNHAGWAGMKIAKLPWTEEEMIQKKSVVEDDAANNSLVKLLTEPKFAKEFGIEHSTYQEMLFGQLFKFLVNACMNPVTAILDCVNGEMKASCGPVFTSIIDECLQILRVAYRPLFQYHEKYSGNEEYPEMDVNAVLTTDNMVSEVTRIGCDINSRNSSSMRQDTLFLRDIEIEYINGYVVKLADNLNLDPNCCKVNKTIGELATMRLALNRSRSINGDWRKD
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MDRGRPSTEVLQEERGQEASPDHDQKTGPSHGPHGIFLRSSQWKAKDGGGGDGAGDGDGDGDGDGDLEMHPRKDRTLPDEDEGASPIANQKDGTGTGCAFCGKSLSSGPILGPEEGKGPPVCISCRKSSPNEGLSDGPRFDNRGGSCTVDVMKEEDCGNADPPGKDCSPEPFKLISRPIKEEIFEEDRESRMPQEKVKKEVSEEDEKSWMLKEEVKGEVFEEKEESWMLEKGVKEEAFEEEEESSMLEEEVKEEILEQEDLRIVEVKVKEEEFEEEISRTPKENSAEIEWSIPTPWLTDELSQSWIQIPKGKKKKNGRSSLGRTALTKSSPDSQTEENPNMCQERQKTRQCPECQKDPQRIKKGDKISLENISTEEKPYKCPECGMSFGNSKGFATHRRVHTGEKPYKCSDCGKSFGRKPYKCQVCGKTLSNKRNLTFHQRTHTGEKPYKCADCGKLFSQSSSLRIHKKIHTGEKPYKCTDCGKGFSHSTNLIQHLRIHTNEKPYTCSQCQKSFRSSTKLNLHMRVHTAEKPYQCSECGKSFSYKSYLRLHKRIHDGEKPYKCQECGKSFHQRQHLVSHQRTHTGEKPYQCLECGKTFSQSSHRNLHQRVHTGEKPYNCLDCGKTFSNNRNLTFHQRTHTGEKPYKCQECGKCFTQSSSLRIHEKIHTGEKPYHCLECGKQFSCSSSLIYHQKTHAREKPYKCFECGKSFGQSQRLMMHSKIHRIKVEAGQDILAVKIL
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MQLELLMEKLRHKTNHLNLTDCAKTFRMTILEKRYNNDSVEKLQYQKCLDLLQTNMKVTSLQSMLERLESISRQAGLKFTADGSGRAFFISSDMFYLEVIVEQGGSVCEVHIQHEGKSEPQTCIEIAVCLNSGNFSKFTSHLQGLCAIYQVSADKKLKAKAFAALSALEMDLVSVSKLQAYRQDIVTLVHKSPLGILMPRVGGLPLTLTYFLSPYDLVNVQSPTIAMTQEKIIENNAGISCTLGIDSSTNFQLPISPLFSVNRNSDGESVPAFSPLSATNSASLPANFVLRMRDPLVLCFSFAQQIKSITGMEIGNWDEPEYLFRSLVKTVSKGQMECPGNEDRISRALHVTLPDQQHSYFITESEDVALKCCCITSIPFCHPSHVPQILAILRRQGLLNVLLSSCIRPKSQTDSGAALTFEISAISLDHMSVTFEHPLLEQMCSVEIDLGMDPTFIRCSLFGADEERSSSDEYATKVLQRCLSIPVTMRAILRQMQSSSSRWTNGSDHQGSFERRFQPHINGDSDSHPGSNGQYGNPSFTGGVGGGFDAGHSPRTHNMGNSDVVMTHQSNPILHASTPKETDNECFGVEMEKSEDVVSLVEDTTSTNRSKTLFPPASESRIPTTLGNADSKYSAILHSSDSVLGVTLNNTTAHLNAVRKPNNDVSLKSDSIDMDVSVIEPVADGNQIIAEDADTLSSNDAVAALLNVTKSKESSSPKNKSAYPSVSITPVNSLHTSSLATTYPNINLERRPGIEIIPFSKDSPSSSIPSSLTITPVGGKPTKDKSKYKDFRLKEGLTLDSETKDRDREKERERKERKRRREGEKSPSSGGSGGKPTKMMNLSATLMGPPGALLKMDSSPKLNHKNSSSGSNSISTPPSNASLSPLTSPSKSSSKSSTPSSSPKHPSSGGKPSMSALSMSALKCTTSPSSKSKKSKDRDRERSDKERDRDKDRDRDRDRDKDKERDRDKERDRDRDRDKERSRDREKKSRTPTPTSNHHHSRGPPLLKTKSLDFSLAVEDKSEESKEDNSFNSILALATANSEMLPSQMDLQSSIHTVTQELLSFSPPILSDSENCKLSGNTGGISADGLMSCPSSGNPNKSPLRSRKSSLSAVIDKLRSQHNPESDIFQNSGPKYTGDSALRMEQSEGRSSYMDEFMEESDSSSSPKPNDAEDNMHFNRIHSGSNSPSDPFSQDDSGINETTDAHEGELNGESLPDKEFVKPFPPPSARGTYGIRPHGFLSNSEADLNPNSPSVSVHIVNVPSPLALQQTRSPLANQLALVTAASGPSPASSTSQSSPCIIDDDLMDEALVGLGK
The following text describes a protein:
Function:
Involved in mitotic DNA repair and meiotic recombination. Functions in the recombinational DNA repair pathway. Essential for interhomolog gene conversion (GC), but may have a less important role in intersister GC than spn-A/Rad51. In the presence of DNA, spn-A/Rad51 enhances the ATPase activity of okr/Rad54.
Sequence:
MGNIDDFSSVDWGEDGGEFLDESMQSSTHRSGRNPSPPVRNRSSQSQAATPSPKLPGIREQLRIIRDAAAHGEIIDFDDNQVRLEPPPCHRAPRPLPPPVVAANIRNEEYNHEEALKTALGSDCEDDSDEESVSNEPSRSPSPSASGDENQEYKVEDDPEFAIADEDEMEDEEEDIPARRGSSEGNRSPRGSRHRRRAIRDDNSNENFFKRYNSLPVDDEDYTITRNVESESGLSSLPWKVDTKSWNRLFPFQKDGVQWLQTKMDHRSGGILADEMGLGKTIQTCIFLRSIAETQRTSYKYKGLDTCLIVCPVSVTHQWVEKLNEWFPRVRVFLLHQTSSTGRERNWADRILKKLGKKSRYYPDGAVVLTTYGTFTNLHKRIVPLPWQVVILDEGHHIRNDDTKCAEAMRQLTTTQRFILTGTPFQNRLKEFWKLIDFVNPGRLSDAKTFDKCFIRIINAGAYINCSPEAAAKAYQCLMALHCAIKPLILRRLQKDHRMELNLTDIEEVMISCELSPRQRRIYQEFCGSIEVQQILERNIKAFGGINKLGDICNHPGIYRKMKPGTEKFGRMHDSGKVVMLFRLFRRWFKNPNNRVVLFTQRLAVVDMLAFYLDKKQIAYCTLTGNNSLPERTRIIKRFEEDLSIKVFLMTTRTGGLGLNLASANKAVIFDPDWNPQADNQAKMRIYRMGQQHKVTIVRLVSNGSIEDRKYFKQIQKENLAEQLLNNADVNHTIPNNTLKDLFTLKPAGLKGSDIGVYIEGDIVPEEGLKSSNKDLKKKAKKDLKHKLEGFEDKKLLLSLFDDDKLVAMRNHARTVQDGACLRAPERKRINEAVESAVKSLLHSEGRLAHGWKKEFHRHLRHSGLKRIKSEYNVEEEKIDGSFWDSITPRFKCNDDKKELDKIVMCARLLHDFLQKCPDGKEEKFLKKILAKQLDFTDPTQTFFFREIISTIAIYNEDTDCWTLKKMYQEARIKRKDAVNTSEDHSPPRSKKHRRSMEDSSNQPSTSTQAYQTDN
The following text describes a protein:
Function:
A short-range repellent, controlling axon crossing of the midline and a long-range chemorepellent, controlling mesoderm migration and patterning away from the midline. May interact with extracellular matrix molecules. Repulsive ligand for the guidance receptor roundabout (robo) and prevents inappropriate midline crossing by Robo-expressing axons; [Protein slit]: Promotes midline repulsion of axons but not longitudinal axon guidance; [Protein slit N-product]: Promotes longitudinal axon growth.
Subcellular Localization:
Secreted.
Sequence:
MAAPSRTTLMPPPFRLQLRLLILPILLLLRHDAVHAEPYSGGFGSSAVSSGGLGSVGIHIPGGGVGVITEARCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRRLRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCSWDELRMKLSGECRMDSDCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCSSENSEGCLGDGYCPPSCTCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQPCQNQAQCVALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLEEGRFSCQCAPGYTGARCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNNSFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVSTMYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDPAQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQKITPGCALLEGEQQEEEDDEQDFMDETPHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYCDQGEGSTEPPTVTAASTCRKEQVREYYTENDCRSRQPLKYAKCVGGCGNQCCAAKIVRRRKVRMVCSNNRKYIKNLDIVRKCGCTKKCY
The following text describes a protein:
Function:
Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.
Sequence:
MKSIARSTHFSLAHLTVRLRNAVVTATSRRAALPSYQVALSSRTFGSTTVSSATSSSSSSVQGSVEIEDKKPKRKRRTREEIEAAKLAKAAFGVPIRSHRRTRRALSGTTVAQAEENPEQRAGKASSKDLIPEGQVNQKSRSVRLPVSEEGAAEQPLSAETMEELLLHMTYDHLPPRNEWKEEFPISKQHLTSYRYFVSNRSTIQDIISHLGITAPERNGEKVTVVEGYSGPGLFASELLKMPQVEKVIALEATPCYLKRIELLKEKLDEKQPGAGARLDTLTESAYLWDTYSHLVSSGKLAHLNNRVLTSDGRTVDFTTNEFVTGAHSDASWQKLSPVIFFTQLPNTVYGEQLFAQIVTAIATRSWLFRHGRIQLGFVCGESLAKRCVAEAGDRMFRGKLGTTVQCLADVQVHRYADDLSPHTHHFFPPTMSVGPRVTVAGSSIIPNSNPSTGLTRTGMAMMTVTPKAMPLVKPMEIEAFEFIARNLFILRTKPVAAALTHVAPGGQNVLKMTSPQQVEKGLIREDEVILPEEVVSDLTNVQWACLARMFEKWPFRPRHLFEEGRIKPDNKRRN
The following text describes a protein:
Function:
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.
Sequence:
MKIIEEIPQKNIIKLMPENLDDLWVLYNIIEEGDKIFAVTERRVQDKGDVIRADRGAKRKMFLGIEVKNVEFDENTKRVRILGTIIHGPDDVPLGSHHTIEIKPFDELSIEKNWKKWQIERIKEAIESSKRPKVLVVVMDDEEADIFEVRDYSIKEICSIKSHTSKKLDYKINEELKKEYYHEIAKVLSEYDVDNILVAGPGFAKNSFYNFISSQYPELKNKIVVESISTTSRAGLNEVIKRGIINRIYAESRVAKETQLIEKLLEEIAKKGLAVYGIDEVKKALEYSAIDTLLVSDSLVRNHEIEKIIDTTEEMGGKVVIVSSEHDAGKQLKALGGIAGLLRFPIE
The following text describes a protein:
Function:
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
Sequence:
MSGILRLAGAARSFSRALAPAAPHHRRLAASAAALAEDDACWTEWEEEEEEARRQRARASAPAAESCPADGGPRGVQWVVMGRPGPQKHAHAARLAEVLAVPYISMGTLVRQELSPTSSLYKKIANSVNEGKLVPEDIIFGLLTKRLEEGYYKGENGFILDGIPRTRVQAEILDEIVDIDLVLNFKCAGNCFMKKRSGGDICSHCGQHFGVSSLVSRERNLSLGSSTWPAQAQHASVIGLENPRMEKLRAYAEQTKQLEDYYKKHRKLVELKTSARPGETWQGLVAALHLQHLDPSPTPHKLTV
The following text describes a protein:
Function:
Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity).
Miscellaneous:
MISCELLANEOUS: 'Secern' is an archaic English term meaning 'secrete'.
Subcellular Localization:
Cytoplasm.
Sequence:
MSGAPPSYSFVALPPRAKDGLVVFGKNSARPRDEVQEVVYFPAVDHEAESKVECTYISIDQVPRTHAIVISRPAWLWGAEMGANEHGVCIANEAINAREPAAETEALLGMDLVRLGLERGTTAKEALDIIVSLLDEHGQGGNYYEDAHSCHSFQSAYLLVDRDEAWVLETVGKYWAAERITEGVRCICNHLSLTTKMDEEHPELRTYAQSQGWWTGEDEFNFAQVFSPADDHLDCCAGKDSLEKQEESITVQTMINILRDKASGVCIDSESFLTTASIVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKAQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAVIESDQEQGRTLRKTMLELEKQGLEAMEEILSSPEPPDPAEVGDLFYDCVDTEMKFFK
The following text describes a protein:
Function:
Involved as a receptor for mab-20/sema-2a in the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, involved in precursor cell sorting and in the formation of distinct sensory rays. Involved in axon guidance of SDQL neurons during neurogenesis.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MLFIESAFLVLTSLSAAEAATPFEGGVKQKVFHSAGHIDDFIVSRDQQTIYIASINRITSLHSSNLSIQNEVSIGPVQDSPWCSADGKSCLKDNRPFSTDVHTKILQILPSGQLLQCGSVKLGSCSTFNSKLSLITEASTPVAANSPDASTVSQIIDNRLVVAASPTKESPGCNPNLPGLNVENAGDLEGEAAVYLRAAYRSSFRFVTTFSHQHFIFVVATVTPRETRLPVTTRLIRFCKNDTKFVSYSEIELQCRGEDNTNYPFLTAVVQTGDKLIASFSASPTSSKNSICVFSMQKVKLTFWYNVDRCRSGTDSIKLSHIGRDTKCVNKAHIPLDEDSCELGVGGSIELVEMSTIDVLAKVTSLMAVDQKALFAGTSSSQIVMLKWDEQNSNKLEEYGRKEIGDGRTGSEVVKMTRFGDFILVQMPYGIVMEELSTCAHHESCTDCQVSVDPLCQWCHPTQSCTTSSRCSGPLTTQCPIVDGDPIPSMVSVNSSTSISFNIHHLPPPVGFVYKCYFGSKSHSKSTKATWTASGISCPSEMFGSPKTFEISLMTSISKNPISRHNFTVFDCAGYSTCSTCMSSEFGCQWCSHKCSSSCGSASAKACVKIQPMKVPIAIGSQQEIVLEALNLDTLDRKTEHFCKVNGQVAPAKIASDSIRCGKIQLAGSNETNANMVVPLSLMANDVVVDIANVSLYSCSNLAADCSSCLALSPSLSCGWCNRKCSHECHESKATAVCDPPKIDRFEPSSGPVEGGTVIKVYGNDLGMSVEDVRGKIYVAGSRCNIVEYQVSNMIACQVDKGVSSGPIKISVGRATMAVAESSDLFSFVRVSIFSAYPLYGPISGGTRITLYGQNLSSGSRISVTVGGLPCPIERINSSTVLTCLTPSGSSIGKSAKVVVHVDHSQIQLDQPFEYRSDPSVNSIFPLSSFKAGGRIVSVQGSSFNTVQSARMFLISSPTPPFEIISDLAPCHIINSTLMTCMTPKILETITRRVEYTRQPVGFLMDNVTAVANLGRRIQMSVYPNPSLSPFKGIRYHQGEQSLILEGHNLNLAAEPNDFKIFVGSERCYVTLVDVRQLVCSGPLKQPKPTDERGVPINGDNPLVTVIVGSLRMELGLIEYSDHALPSRLSFLILGLLLFTVITLIVMCLIFKRRRQEREKEYRKIQLQMENLENNVRKECKQAFAELQTNLVLSPKSTGTITSPELIHFPHFVENLLWADQNLTSAPSLARTLPVTLAQFHALLSFKGFIFTIVEAAESDVSISTSEKSTLASLLISVLLRNFSYCTEIVVDLLKAHIARSVQAKRAELLFRNSDSVVEKMFSKWMSICLYSHLTPQMNSYFYLYKALQYQTDKGPVDAVTGDARYTINEAKLLRESVETKTLKIHIVPFEKCDETTHLEVHACDAICQLKQKVASAVYKETPYSQRPRITQFELKLKCAKRGDIKLTDVSAVETLSQKKLPVKLLTLADYGIQDGATLEMTSAVYTAESYRNSLADSGQSSWSSLDRCSPIYSSSKYYHLTNPSSGTMTFKKRTSPSEIPKSIPEVYLTRLLTSKGTVETYVEDFLESVLYMHDSSYPPILKFFFDILDREASINGVSENICQQWKANGYVLRMWTNFVKNPQLVFDVPHSVSMDANLSTVAQTMMDCFSFSEPVLGAHSPSSRLLFAKDVARLRPLSVDLFKRVKNSPPLGMEELRTELVNMANDVSTCKGSSLALSELLSWVRGNGIRISQLLSSNQETSQQRLPQKLSQVLHVCLETDNHIYSTISDYD
The following text describes a protein:
Function:
Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
Subcellular Localization:
Nucleus.
Sequence:
MSRSMRSHGRDWDDDTPSRSSLISSFAACEARWSKLAEPADRLMRLPNKLTSTYVDRYGRTTFDDTYALGWTSTRPPPIGHNHPKIIRARNNGNWSEKLEAYYSELPPNYNIPLAGQACKKADEDWSSRSSTRVATPFRVDFGPFTILLEALAKIRKPREPTAGKKMWECRFTPKDVEKEKEDNFHNRPSIKLPLPDHVKALLVDDWENVTKNQQLVPIPHVHPVDEILKDYLEHERPNRVPESPQMDILEETVAGLREYFDRCLGRILLYRFERAQYHEQHLIWTAGTDEKHKSASDTYGAEHLARLLVSLPELVAQTNMDQQSVNRLREELIKFTNWFSRHTTKYFVSEYETPSQEYVDQARSV
The following text describes a protein:
Function:
Putative tyrosine-protein phosphatase required for protection against superoxide stress.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKIVPPMNFGLVEDGFYRSAQPSELCFSFLEKLNLKSIIWVGAEEPSDIFLSFIESQGIKLYNLAPQTSLNPHFPPPYTDSGVVPISGQYHLPPLPPPPEPLIIQALTLLLRPSTFPTLLCCNMGRHRTGTVVGCYRKLQRWALSSILEEYRRYAGMKVRVLNEQFIELFDTDLVSITAEQVTK
The following text describes a protein:
Function:
Involved in peroxisome biogenesis and matrix protein import. Required for pollen maturation and in vivo germination via its role in peroxisomal function, which partially involves jasmonic acid biosynthesis. Transported to peroxisomes via the interaction with PEX19-1. Required for peroxisomal protein import by acting as an anchoring protein for the AAA ATPase complex, which consists of PEX1 and PEX6.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MEATDIWGEIERSESYLVCSMYEEAESLSSSILKRIFGNIDVLSDEASQGDHQFHDMLESAGMVLVQSLHGIGRTVEIVNELRDVFGEVAAIPVQVLLTGVCLQISNGSYLGVRDILEEFFRIWVYKDNHYILNDAGVSTKGFHAKNCLDIDEYMEVVELYTFGVLAKFSNDMGLAISWVEKAALPEERRQGILRRLHSLLSLKTASSFEENSKDSSYAVVNNKKSLGNEKNDEIDSFLKLSKQHEPWSLWSSHPLSLKVGNTQFSMSRGKVAVSLVGLIICYALKRKRAALIRIIRRQMESTRKAIVDFWKLAFSYQVNPLAAIQSIPSTTT
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Sequence:
MKIIRSMRTQLKYYLENQSERVKTAVFHPTATLLMCSLHNGDIQIWDYRTKILLHTYPHAHNGAVRGLCFHPNRPLVVSGGDDCVIRMWNYRDSHSDNACVGEFKGHSDYIRSTYFHPTKPWILSCSDDRTIRIWNYLSFKCIAILTGHDHYVLSAHFHPRSEIPFVISSSYDTTVRVWDIKDLYENEPRGDGAVDLAGSVKFNITPEQFAVNNAIFHPTLQLIFTCGDDKTIKMWRYNDSSCWSEGTFRGHTHNVTACTVMGDYLISVSEDKCVNVFDIKTQKLIRSFRTNGRIWCIEKHPLENLFAIGCDTGLKVFKLESERPAYFVTGKSVYYQTASSINKFDMSTNEIKLMYSLNHVQSIVAIPQAKEMILASNGESHEAICAAFHRSNLQGTSLCYIGGSFYLSYEPRSNTVQKIDVGKSQVVGKIQLERSGTRISAVNRPNTFCLFGDDFAQIITVEGNILFKVDANGLKRTVATKETLVLFGSQTILLLKDSKDGYEIVTRYTETTHIKSVVIATRGVILYTTNAHIKYLLPTGEVGIVQGTGNEVLYLIAATANAKGLLTIDINGDIATKVVDLADVDFKAAVLRGDLAAIHKHLTNTVFIGDSIISFLMKYKFAELALLFVRDVHAKFAIALQCGNFKAALEAAKQLNLPQYWRQLSQKAISTGHFKVAEFSLVQLGDYSRVSYLSAYCGNIQSMVKLNKLEASNSQKLILSLLSNDQKTMVKECFIANGKLGYIAAKTRGFDEIAERISGEVEISEKLKEFATKERKPIPGSVIKMNLSSLKEWPHIGVEKSIEQDLIEAKEVNLNEEKPVFDGVKVDQIVMEKKEENKPISSKKQQEPITNEKKEDSDDENWDFI
The following text describes a protein:
Function:
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MAGSALIPGLNNWLVLGLLLLSGNTCSRIWQHPRFVAKKRGSTVEIRCHVEDDGLVSWFRKPKPDSEPKTLHAEQGRILQSHNKSEAVLTILSVQFQDNGIYFCKQECAKGTQRTEHGCGTELRVMGFSTLAQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MCFKIERNTIWYRQEIHQAELWCLGGIGCPSWRQVQFQNCCNNALYKELWDACAGPLVTLPREGERVYYFPQGHIEQLGAPIQQQSEHQMASLNLPSKILCKVINVQCKAEPITDQVYAQIMLLPEPEQIDVISPDPPLPEPERCVVHSFRRILTVSDISSHDHFFVDQKHAEHCLPPLDMSQQLPWQELVATDLNGNKWHFQHIFQGKSNKHLLTTGWSAFVSSKKLVSGDMFIFLRGENGELRVGVRRLMGRKTNILSSATSNQIRHSLLAVASYAISTGSLFCVFYEPRTSRSEFIVSVNKYIEARNHKFCIGMRFLMRFEGEEVPIERINGTIVSMETSPRWPDSEWRCFKVRWDEPSLIVHPERVSPWEMENISSSSQPVPRTKRSRSSSPGAMEISPSSTQPGPRIKQLRSTVFLSQTPDFGMWIFPAEVPGFSNCDLYLSSSSSTNSKTYSSDFRGDSSQASTSPNRVVYVTESAPSVNKDFGMEEDGCPVLSLENESDQHSETANINQSEKLSVISCDTEKLCSKKQITSCAEVRMQGIALGRSIDLTKFKCHEDLIKELENMFEIEGELSGSTKKWLIVYTDADSEMKLVGDYQWEVVCNMVKKILIYRLG
The following text describes a protein:
Function:
Could induce apoptosis in a BH3 domain-dependent manner. The direct interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.
Subcellular Localization:
Mitochondrion.
Domain:
The BH3 motif is required for pro-apoptotic activity and for interaction with pro-survival Bcl-2 family members.
Sequence:
MPRGRCRQQGPRIPIWAAANYANAHPWQQMDKASPGVAYTPLVDPWIERPCCGDTVCVRTTMEQKSTASGTCGGKPAERGPLAGHMPSSRPHRVDFCWVPGSDPGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLPLPDDYELFCQDLKEVVQDPNSFAEYHAVVTCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSPGF
The following text describes a protein:
Function:
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Testis PA2 may be important in the production of prostaglandins, by the release of arachidonic acid, which in turn are necessary for the contractions of the seminiferous tubules and the testicular capsule; they also seem to decrease sperm transit time through the male reproductive tract.
Subcellular Localization:
Secreted.
Sequence:
MKGIAIFLVFIFYWTTSTLSSFWQFQRMVKHVTGRSAFFSYYGYGCYCGLGGKGLPVDATDRCCWAHDCCYHKLKEYGCQPILNAYQFTIVNGTVTCGCTVASSCPCGQKACECDKQSVYCFKENLATYEKAFKQLFPTRPQCGRDKLQC
The following text describes a protein:
Function:
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. May participate widely in the construction of cell envelopes in cornifying epithelia characterized by either increased thickness or a requirement for extreme flexibility.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSHQQKQPCTVPPQLHQQQVKQPCQPPPQEPCAPKTKDPCHPVPEPCNPKGPEPCHPKAPEPCHPKAPEPCNPKVPEPCQPKVPEPCQPKVPEPCNPKVPEPCQPKAPEPCHPKAPEPCHPVVPEPCPSTVTPSPYQQKTKQK
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQ
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAFSFGQQGSSIKAPSIGSTGVFGQSNTTKPTAPFGSGSIFGSTNTNVGAGGPTGSSSAPPFGNSIFGKTQQQPTTSFSNTTTNAPQSTVFGQNAASRTGNSNTQPLFSWSTVNNPTKPVDETNATIPSSLLLSSGISPNATVSNAQYGPAQPPSVEEQVQKILNAWNLNHPDCAFQRFFYNKVPVEQAALYVKPPNYNQQKWDEAVANRPSNSVVPVLAVGFPDVQKRINMQIQQVNTYRIRMREIVETLGRLSNKHDLDFSIKLAEAKNRHVRLSERILRLAIKVHVLRHRGYALKPNEEELRKKLDDLTKSLNNPEIFGRLNEIWARITLIFEGEKISEDQRSNLAKGVVDWRKNSDQLEVITDVLRDHQVGLSYVVKLMQEDLATLNKQLTEHVPQSQK