lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Substrate-recognition component of the SCF(FBXO46) protein ligase complex, which mediates the ubiquitination and degradation of target proteins. In absence of stress, the SCF(FBXO46) complex catalyzes ubiquitination and degradation of MTOR-phosphorylated FBXO31.
Sequence:
MDRGSLLPFQLWCPRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGTADTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGGGRAGREEGR
The following text describes a protein:
Function:
Low-affinity transporter for external inorganic phosphate (Pi) probably involved in the acquisition of phosphate released by arbuscular mycorrhizal (AM) fungi (e.g. Gigaspora gigantea, Glomus versiforme and G.intraradices) during AM symbiosis; required for propper mycorrhizal arbuscule morphology. Acts as a Pi-sensing machinery at the root tip level, independently of AM fungi, involved in the regulation of early root branching and lateral roots formation.
Miscellaneous:
MISCELLANEOUS: Although related to the sugar transporter family, it does not transport sugars.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Present on the periarbuscular membrane in cells containing arbuscules during arbuscular mycorrhizal (AM) symbiosis with AM fungi (e.g. Gigaspora gigantea, Glomus versiforme and G.intraradices).
Sequence:
MGLEVLEALDSARTQWYHVTAIVIAGMGFFTDAYDLFCISTVSKLLGRLYYFDPSTNKPGKLPPSVNNVVTGVALVGTLSGQLVFGWLGDKLGRKKVYGVTLIIMVACAICSGLSFGSSAKSVMITLCFFRFWLGFGIGGDYPLSATIMSEYANKRTRGAFIAAVFAMQGVGIIFAGLVSMVFSGIFKAYYQAPRFNEDPILSTQPEGDLLWRLILMIGAVPAAMTYYWRMKMPETGRYTAIVEGNAKQAAADMARVLDIEIIAEQDKLAEFKAANDYPLWSSEFFNRHGRHLIGTMSCWFLLDIAFYSQNLTQKDIYPAMGLIRQDKEMNAIDEVFQTSRAMFVVALFGTFPGYWFTVFFIEKLGRFKIQLVGFFMMSFFMFVIGVKYEYLKDENKNLFALLYGLTFFFANFGPNSTTFVLPAELFPTRVRSTCHAFSAASGKAGAMVGAFGIQYYTLDGTPRKIRRAMMILAFTNLIGFFCTFLVTETKGRSLEEISGEDGRESELTATPNDRAPGIRQDSRTEKM
The following text describes a protein:
Function:
Transcription factor involved in phosphate starvation response. Acts as a positive regulator of phosphate homeostasis and phosphate signaling by antagonizing SPX4. Transcription factor involved jasmonate signaling. Regulates shoot growth inhibition in response to jasmonate. May play a role as transcriptional activator in the regulation of jasmonate-mediated stress-inducible gene expression. Possesses transactivation activity in vivo.
Miscellaneous:
MISCELLANEOUS: Overexpression of BHLH6 promotes shoot and root phosphate accumulation, and root hair growth and acid phosphatase activity under phosphate sufficiency.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDAEMAMGESFAYYWETQRYLESEELDSMYLPTQDDSNYESSSPDGSHSSSAPAPAAVGGDAAAAVAGSGGGMTTMMMGGGGGGGDDAGGANKNILMERDRRRKLNEKLYALRSVVPNITKMDKASIIKDAIEYIQRLQAEEQQMLREVAALESAAAASAAPAAANPFAGLGADEEHEYGHHHPSSSSERTKKVKRALSVSSISDALLAAAAPAPPVEIQELRVSEVGDRVLVVSVTCSKRRDAMARVCRALEELRLRVITANITSVAGCLMHTLFVEVDHMDSVQMKQMVEAALSQLVATGSPLSSMSY
The following text describes a protein:
Function:
Necessary for normal cell division and for the maintenance of normal septation.
Sequence:
MTDDKDAKLIEAGRKLFARDWQFIWASPSIQTLPPMDGVEIAFAGRSNVGKSSLINALTGRNALARTSHTPGRTQELIFFEVPGKKDLRLVDMPGYGYAKAPKSQVASWTELIHKFLLGRASLARVYVLIDARHGLKDVDLEILGTLDRSAVSYQIVLTKADQVKPSELASRIAETEAALAKHPAAFPNVLATSSRSATGMAELRAAMAKLLEERSS
The following text describes a protein:
Function:
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.
Sequence:
MTDGTCLRRRGGPYKTPPATDLRHWRLSNEEGRQRWTYCPRGATQDPPREQTLLKTFCRGLATSHYFEELPPAQTALEGALKGLKFYSKLQAEDGHWPSDYGGPLFLLPGLLIACHVTNTSLPAEHRKEMIRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRLLGLGPDDPDVVRARTNLHQKGGALGIPSWGKFWLAVLNVYSWEGLNTLLPELWLFPTWMPAHPSTLWCHCRQVYLPMSYCYGTRLRGPEDELVRSLRQELYVEDYSSIDWPAHRNHVAACDLYTPHSWLLNLTYVILNLYESCHSASVRKRALATVFDHVAADDRFSKCISIGPISKTINMLVRWSVEGPTSPVFQEHVSRIADYLCGHSGLFSSWLQGTNGSQLWDTAFAIQAFLEAGAHKLPEFSACLKGAYKFLRLTQVSRTRASASEPGACGGVWGPQPQGRIMIDYSYVECTSAVMKALKRFQACYPEHRAGEIRHTLDEGLRYCLRVQRADGSWEGSWGVCFTYGTWFGLEALACMGHTYGADGPSSLLGRHPNIDAVERGVAFVLGKQQPNGDWPQENTTGVFNKSCAITYSNYRNIFPVWTLARFSLLYPQHRLAGSARTM
The following text describes a protein:
Function:
Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the CDC2 protein kinase to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
Sequence:
MNENDENGPSTRLTRAKAAALTTDAPAANGALKKPLQTKKAATGANGTQRKRAALGDVSNVGKADNGETKDAKKATSKTGLTSKATMQSGGVQKLSRSNLSRTAVGAKDNNVKKPATEAKRPGSGSGMGSAMKRTSSQKSLQEKTIQQEEPPRKKVDIEKVVEKQAEAVSVKGDVKAGAQTEELEKPQDFVADLDTEDLDDPLMAAEYVVEIFDYLRELEMETLPNPDYIDHQPDLEWKMRGILVDWLIEVHTRFRLLPETLFLAVNIIDRFLSAEVVALDRLQLVGVAAMFIASKYEEVLSPHVANFSHVADETFSDKEILDAERHILATLEYNMSYPNPMNFLRRISKADNYDIQTRTLGKYLMEISLLDHRFLGYPQSQIGAAAMYLARLILDRGPWDATLAHYAGYTEEEIDEVFRLMVDYLHRPVCHEAFFKKYASKKFLKASIMTRQWAKKYHHLYIDSALTEPYNSIKDNE
The following text describes a protein:
Function:
May act as a component of a corepressor complex that represses transcription.
Subcellular Localization:
Nucleus.
Sequence:
MDDVGALNHLLPVDALRLRVGLQCTSEVTTNQCYVEKLRTLKAFHAAKCTLQVHTQFLQTLALPAEGSAGVSAHPPSCALGNSEEENSEDEAPRDSMIRVGSDYQAQIPECKPDYTSPSNNVELKGMLVWSPNQLVCDTKLDEYITMAKETHGYNVEQALGMLLWHKHDVERSLADLANFTPFPEEWSVEDKVLFEQAFSFHGKCFQRIQQMLPDKMIPSLVKFYYSWKKTRSRTSVMDRQARRLQTKREEGAEHVTSYKLYFFILSLLFQVQNIKQINSSLKGSLEGGISEMRPPELNLKLNARWTTDEQLLAVQAVRKYSKDFQAISEVLGNKTPPQVQITSVSSSSQTAPPAAATTTAATTSTTAMSLPPPLLRPTIPSAPALHRQPPPLQPGRLLQPRPPPLVRPAPRQSPRAPPALLGSHAESTFS
The following text describes a protein:
Function:
May have a photoreceptor function.
Sequence:
MTRNILIALLRNDLRLHDHPILHVCSEPTPSTANFTQPITHVLPVYVFDQRHVEVSGFPRLEKARKDGGGKGSGEYAKTRELGLWRTGIHRIKFINESVFDLRDRLRRLGSDLAMFAGTPESVIASLIHQIRAHGDTVEAVYLSREINTEEVNIQKRLQRMLSDVQCRMHMFETKSLIHSRDLGFPVSKLPDVFTHFRKQVERNRIWRAPLASPDRLKPFAEVPVEDAAGVYSLSANKQHGLDRKNAVEKCLLQPLLDNPVLAHNELLARVMCKRGQVDVAHSAFPYRGGETEALARLDHYFDRSDSCPAASYKQTRNQMLGTDYSTKFGAALALGLLSPRLIAQKATELDNATHDATHNASNKGGGYWIIFELLWRDYFYFVGWKFGSKLFSLRGIEDDISARSAPSKASEWKSSASLSDRDDGFVRWCTAQTGVPLIDANMVEMVQTGFMSNRGRQNVASFLTKDLGWNWRHGAEFFESWLVDYEPNSNWGNWQYVAGVGNDPRSSRQFNPIKQGNDYDANGEYVATWLPLLSDMPPQYRHHPWTCPDAAWAEQAHSAHYPPTPIVEQQMWRKHYSNPEGAPPAHHKPDHVATGRRSANANANRRGARRRSRSTRASTQQS
The following text describes a protein:
Function:
Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MTDLLDPSALLQVLQQQLLPTSSPSPLLRNPADALAAIIHTIMTRLDFRLTGLSEDDRLAPSSSESPTSSSTNKLPPEWNAKGPDHYSFRYKHHQSSLDYLVKIVKLGNKAVIHGVALQGTKTSTMEVVLSDYLSSAFWPYPREGKDEEMLVNGYIGSSRLKDLTSAFKIQVLQQLVPGLRKDGYVEENSSNASSGGGGGERSSTQSSGPSRPTAGTTQPRPPLAADEDDPSLPSGYQPPFRNPLIIGDRDLDPLGGSPLALPPRFGGGGGAGFAPPPVFPGGDTGGGMFVGPNHPMFRNRYPPQGTGLPQGAVPPGARFDPIYPGGAGPEASHPDVGGARPQNFGGEPDWDELAPPRGENPFGARGARGRGGGSAFGGHSDTAGWYA
The following text describes a protein:
Function:
Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B. Necessary to mediate a specific antagonistic effect of inhibin B on activin-stimulated transcription (By similarity).
Subcellular Localization:
[Isoform 1]: Membrane; Multi-pass membrane protein; [Isoform 2]: Secreted; [Isoform 3]: Secreted.
Sequence:
MMLRTFTLLLLCIWLNRGMTSMAAVESQPELWIESNYPQAPWENITLWCKSPSRVSSKFLLLKDNTQMTWIHPPYKTFQVSFFIGALTESNTGLYRCCYWNEKGWSKPSKILELEAPGQLPKPIFWIQAETPPFPGCNVNILCHGWLQDLVFMLFKEGYTEPIDYQVPTGTMAIFSIDNLAPENEGIYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPILAPGESLSLRCQGPIYGMTFALMRLEDLKKPYYYKKPIKNEAYFYFQALKTQDTGHYLCFYYDGSYRGSLLSDILKIWVTDTFPKTWLLVQPSPVIQMGQNVSLRCGGLMDGVGLALHKKGEEKPLQFLDATSNTGNNSFFLKNVTYRDAGIYSCHYYLTWKTSIKMATYNTVELIVVAWPSSVFKVGKTITLQCRVSHPVLEFSLEWEETTTFQKFSVDGDFIITNIEGQGTGTYSCSYRIESHANIWSHRSEPLKLVGPAVTGFLPWNSILNEAIRVSLTVQFLSLLLLVLWLQWKCRRLRLREAWLLGTAQGVAMLVILIALLCCGLCNGALTEEIEIIMPTPKPELWAETNFPQAPWKNVTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDILPKPVISASLPIRGQELQIRCKGWLEGLGFALYKMGEQEPVQQLGAVGREAFFTIQRMEDKEEGNYSCRTHTEKQPFKWSEPSAPLELVIKELYPKPFFKTWASPVVTPGSRVTFNCSTSREHMSFILYKDGNEIASSDPVWGNPGTSTAHFLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELIVTEFYPKPTLLAQPGPVVLPGKNVTLRCQGIFQGMRFALLQEGAHAPLQFQSASGTSVDFLLHTVGAEDFGNYSCVYYETTMSNRGSYLSTPLMIWVTDTFPRPWLSAEPSSVVTMGQNVTLWCQGPVHGVGYILHKEGEATSMQLWDSTSNEGAFPIINISGASIGRYSCCYHPDWMSPIKIQPSNTLELIVTGLLPKPSLLVQPGPMVVPGENMTFQCQGELPDSTFVLLKEGTQQPIEQQRPSGYRADFWMPVVRDQDSGVYSCVYYLDSAPLVASNHSNSLEIWVTDKPPKPSLSAWPSTVFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSEDGDFVIGNMEGKGIGNYSCSYRLQAYPDIWSEPSDSLELVGAAGPVAQECTVGNIVRSTLIVVVVVALGIVLAIEWKKWPRLRTRGSETDGRDQTIVLEECNQDGEPGTATNSPSSALQGVSVEQTVPI
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTRVKTVMTNENNKYDFIFKGINLTKSIFIVGLVIRLVLIVFAEWQDANMLVKYTDIDYVVYTDASRAVVNGLSPYDRSTYRYTPLLAYLLVPNILIHPAFGKLLFVICDMIIAYLLKGILLERFPKITSRTLLICLASWLLNPFSINVSTRGNAESVIGAMVLASFYFLTKKNLTLASIFYGLSVHFKIYPIIYSIPMYLYIDENFFSRKPSEYTSLNNNFKNIFKNFFNKNRLKFFLISAFTFISLTFIMYLIYGYIFLFETYLYHVIRADNRHNFSVYFYQIYLNTPIVETVGDLVGKVNGSNMIVALASFLPQVILLLAITLVYFNDLEFCLLLETITFVAFNKVCTVQYFIWYYSILPLVIPSSSLGLVQYIILFAVWMGSQGLWFYSAFNLEFLGLQTFWNIWVAGLLFFIANIYILVKLILNHNPIKVNQYLKSK
The following text describes a protein:
Function:
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Note=Localizes in the kinetochore domain of centromeres. Colocalizes with PLK1 at the interzone between the inner and the outer kinetochore plates (By similarity).
Sequence:
DRPRPARLSHARFSKNHSGRTHSMKDKAGRKHRPLDVFDFPDHSQLSSFSRLGENEKDEESYETFDPPLHSTAIYADEEEFSKQCGSHLPSTPQEKEAKRSSDTSEIEASENESVKISAKKPRRKLKPISDESESPEESDVRRKVKPTENISTQHEAVSATALPGLSEKPAEAVTPQKTGPQSAESSAEKATLATEHQLETQKNKMLPGKRKKPRSYTTDTSDCAPVWCLKEKKASEIMELDVFLSAFENILLEYEQKIDSRVCKAAINKFHSNLKEELIKMVQEIQMLKTLKRKNAKIISNIEKKRQRLIEVQDELLQVEPELKQLQIKYEELQERKASLRKAAYFLSNLKQLHQDYSDVQEEEPSVKETYDSSSLPALLFKARPLLGAEHHLQNINYQLENLLDQK
The following text describes a protein:
Function:
tRNA uridine(34) acetyltransferase, which mediates formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. The proposed mechanism is the following: (i) recruits S-adenosyl-L-methionine and cleaves it to generate a 5'-deoxyadenosine radical (5'-dA) in the radical S-adenosyl-L-methionine (rSAM) region, (ii) hydrolyzes acetyl-CoA in the N-acetyltransferase domain and (iii) an acetyl radical is formed by the products of the two domains and (iv) is transferred onto the C5 position of uridine(34) in the bound tRNA molecule. Does not show protein lysine acetyltransferase activity.
Sequence:
MSSNADDGAFQAACEELVSRILAGDVGKDDIEDAKLDVCGEYAASKVPKHSDLLDVAPDGRRDELEDVLQRKPVRTASGVTPVAIMTSPHTCPHGKCLYCPGGPASEFTSSQSYTGHEPAAARGVQNDYDPYGQVTLRLHQLRQIGHPVDKVELILMGGTMTARSHDYQEWFVKRALQALNDFDPDQEPAPNQTESFAQDPAEYDFRYLEDVIADNEHGALRNIGTTFETKPDWCDPEQVDRMLDLGATKVEVGVQTTFERVNREMHRGHGVQASVDANRRLRDAAFKVGFHMMPGQPGMSKEMVLEDFRRLFDDERWKPDYLKIYPTLVVRDTITYDMWRNGDFEPLHNEEAADLVAEIKDMIPRYTRLQRVQRDIPADFIDAGVWKSNLRQLARQRMAEHGYTCDCIRCREAGMNDDDPENVSLDVETYAAGGGTEQFISIEDFQQDLLVGFARLRFPNEPAREELTDAALLRELHVYGSEVSVGDDTGDDQHQHQGYGRQLMERAEHLAADSGFEKLSVISGIGARQYYKQQLGYHQDGPYVSKRL
The following text describes a protein:
Function:
Catalyzes the cis-trans isomerization of peptidyl prolyl bonds and accelerates protein folding (By similarity). Also exhibits chaperone-like activity.
Domain:
Contains an N-terminal PPIase domain, an IF (Insert in the Flap) domain and a C-terminal domain (CTD). The CTD mediates dimerization. Chaperone activity requires both the IF domain and the CTD.
Sequence:
MVEKGKMVKISYDGYVDGKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDEAILEMDVGEEREVVLPPEKAFGKRDPSKIKLIPLSEFTKRGIKPIKGLTITIDGIPGKIVSINSGRVLVDFNHELAGKEVKYRIKIEEVVDDKKNIVKEIVKMYVPRLSDVKVTIRNGTVKIELPEFAPFIPNIQTAKMAIANEILKRLEDAEKVSFVETFERKKETKEENK
The following text describes a protein:
Function:
Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Catalyzes the equilibrium isomerization of retinols.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGNRVAREDFEWVYTDQPHASRRQEILAKYPEIKSLMKPDPNLIWIITMMVLTQLVAFYLVKDLDWKWVIFWAYAFGSCINHSVTLAIHEVSHNSAFGHYRAMWNRWFGMFANLPIGVPYSISFKRYHMDHHRYLGGDGIDVDIPTDFEGWFFCTTFRKFIWVVLQPLFYAFRPLFINPKPITYLEIINTVIQVIFDITVYYVFGIKSLVYMLAASLLGLGLHPISGHFIAEHYMFLKGHETYSYYGPLNLLTFNVGYHNEHHDFPNIPGKSLPLVRKIAAEYYDNLPHYNSWIRVLYDFVTDDTISPYSRMKRHQKGKVVLE
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSSQLLKLTHDALKILGIGPKSNKIYSFLLLTTLTLLVILSSIDRPYLKSYTYIKLVVSVLMDFIAYFFNFWTILFSRSDFFQQFECDNEPKLRHYLIFIFVNVFFWVIILMSNYAFTRIILLKSVLEIVIIDIEIYSQFLYGFMIYLILDTIKSKYRQMHRLLANYKVITSDEFFYLVSKIESLACELKNTVDDFNDIFGISFLLIISYSTLHFVNYIDDLFFFRFEKSKFEPFLISNISLVSLIFLFNCTLIIMCDCVRSEASKVVKNAQKLRHKFDLKTLVLNFPKFTAGGFFHVKKSTIFSILNTVSTLLIVMVQFDKER
The following text describes a protein:
Function:
Plays a role in the establishment of cell polarity and epithelial lumen formation. Also plays an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cell junction. Note=Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle.
Sequence:
MKPSLESDEEEELGALQKTLRERANRSIQHLSSMLAGHSSDSETSEPNQQELLSSVQQNPCSPVQQSEAVSQLRSLLQMKTKDANIQSLSPSRRKLAAKRATDDGSSSQPGVHNLVPIINNQSEYIQHLEAEVKFCKEELLEMKQRVRVVIVENEKLHHELKAKTIEDTLKEYTFVDSTLNMEHTAENTLKERLGSVNQAEDHKWRKEMEQLKCLYQAQTETLEAQVVSLKKDLACIQKEYEESKERLRHKEAMAVAAGTGQRVSGLCLKCAQHEAVLAETHTNVHVQSIERLTKERDELMTVLCSLRASQTDAQQREWGAYQQVKQAVEMAEEANLEKTRALVQCEHFHNELTRQRERLERELASEQDKISQAREAARSESKKEREELMQTLSSLSQKVAELQGLLDRGERDRNSLNSQLEEAYKKLTVQETDSSKMCAELRFLLSQAQLKKEEAERDVRDISSKLGRQLELAEQEVQKLGVELSGYRQRLEEAQRAEGRARAEAAGLAEGLSRAQRQLHLTRQEKEASERCCGEDMAALTFQAQRRERELTQTLQQMEAQHEKSVRETDALLSAQNSLIRKLKEECHTLGAKLEELAQSSRAEMEQLSLEREHLQESAEKLRGRCEEMEEQCVQHGRMHQRMKQRLQQLDQHCQASSQQVLQLLSRQKQLMQERQQLTEDLHSLKSQVHAGKRMDRLAV
The following text describes a protein:
Function:
Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MADFKKLHLQSYSLLNRKESLKDSPYWKNLQFPITIKNSGAVTQINFSPIEPYNYLVANSTRVQVYSIKSNAPSKTPHQFHDVVRSACYRSDGQLITVGCDDATLWVIHQKHFKQVFNGHSRSVYLAKFLDNYKLFSGSDDKTVKIWDLATKSEIITFNEHEDYVRCGNKGASNDLFITGSYDHRVKLFDSRCKLSVLTMNHGDPVESVVMYPSAGVIASAGGTSIKLWDVLSGGRLMGSMNNHHKTITSLCFCDNRRRLVSASLDRHVKFYDISTNNVTYSLDYPTPLLSIDIAPDDSLIATGSIDGMLTLKHRKSDEEVDRERLEKRMRKKRSSNSSVPIIKKFQPSADGNDVTLHHRRKEMLSKYETYLKTFQYSKALDEVLETTLRTIHPEVTMTMLDELRRRQALNGALAGRTDKDLASLLTFLLKNFVPPHISTVTEVLNTVLDVYQDQLMDFPLSLIQLSKLLQVSKDRIDFIDEGLGIVGILKSIFASSNINSNII
The following text describes a protein:
Function:
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MSSYGGSGGYQRDSYRSGGGGGYSNGYSNGHGGGYGGRGGGYGGGGGSGYGGGYGGGGYGGGGYGRGGGGAGAGAGGDRMGNLGSGLKKQDWDLDTLPKFEKSFYKEHPDVTARSQREVDEFRKKCEMTVQGRDVPRPVETFDEAGFPQYVLSEVKAQGFEKPTAIQSQGWPMALSGRDVVGIAETGSGKTLSYCLPAIVHINAQPLLAPGDGPIVLILAPTRELAVQIQAEISKFGKSSRIRNTCVYGGVPKGPQIRDLSRGVEVCIATPGRLIDMLEAGRTNLRRVTYLVLDEADRMLDMGFEPQIRKIISQIRPDRQTCMWSATWPKEVRQLASDFLNNYIQVNIGSMDLSANHRITQIVEVISEFEKRDRMIKHLEKIMENRGNKCLVFTGTKRIADEITRFLRQDGWPALSIHGDKQQQERDWVLNEFKTGKSPIMVATDVASRGIDVRDITHVINYDYPNNSEDYVHRIGRTGRAGAKGTAITFFTTDNAKQARDLVTILSEAKQQIDPRLAEMVRYSGGGGHGGGYGRWGGRGGGRGRGGNFTASNAAPLGNNRRW
The following text describes a protein:
Function:
Has antifungal activity against C.albicans. Has antibacterial activity against the Gram-positive bacterium S.aureus and the Gram-negative bacterium E.coli. Lacks hemolytic activity against rabbit erythrocytes.
Sequence:
MSAHKVQIGLSSGQFRVALQVPSVRLKGLGSFHTGSIVLPSQGSLREDQISLHNQDGLHKVMREVLGYERNSYKKFFLR
The following text describes a protein:
Function:
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
Domain:
Contains a central domain (substrate domain) containing multiple potential SH2-binding sites and a C-terminal domain containing a divergent helix-loop-helix (HLH) motif. The SH2-binding sites putatively bind CRK, NCK and ABL SH2 domains; The SH3-binding sites that bind to the SRC SH3 domain are required for interaction with CRK and are implicated in promotion of serum response element (SRE) activation. The SH3 domain interacts with PTK2/FAK1.
Sequence:
MAIATSAQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPKPSLCPASPTQPGSSCPTPERGCEEQEVYVIPPPARPCSASGLPARSCSPSSDSIYKVPRGNGMQLTASRDVAEVYDVPPNILRAPSSCPYDSPASFSCPVAPVVPQPPREDEAPYDVPLALKPPAELERDPEWEGGREPGPPLYAAPSNLKRASALLNLYEAPEELLANGESRDADEGIYDVPLLGPEPPSPEPPVASSSTDLDTVAQLPTRSSPPQHRPRLPSTESLSRRPLPALPVSEAPAPSPAPSPAPGRKGSIQDRPLPPPPPCLPGYGGLKPEGDPECREVANDPAGPHNEYEGIPMAEEYDYVHLKGVDTAQGSRPLDKAFPVDPELLERGLAERKEALSPEEPLVLSTGDLQLLHFYAGQCQSHYSALQAAVAALVASTQANQPPCLFVPHGKRVVVAAHRLVFVGDTLGRLAASAALRAQVGAAGTMLAQTLRATVLAVKGAALGYPSDTAVQEMARCVAELAGQALRFTTLLDGLLP
The following text describes a protein:
Function:
Controls the level of cAMP in yeast cells, together with the low-affinity cAMP phosphodiesterase (PDE1).
Miscellaneous:
MISCELLANEOUS: Present with 6510 molecules/cell in log phase SD medium.
Sequence:
MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDSLMVALYKDRVSPFPNVHNFETGVSIVLYDPSKFQLSVRQLDVLFKRFFPSFNISAIDHTREENLQRLECVERENSICRNRITRINHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEANIYTLLLHLNDSKAQHLRKASVPRLIRNIEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDNPVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLSISKKKFDFISEAILATDMALHSQYEDRLMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEFNDCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ
The following text describes a protein:
Function:
This is a 2S seed storage protein. Has antifungal activity. Inhibits spore germination in H.sativum (IC(50)=62.5 ug/ml) and P.betae (IC(50)=62.5 ug/ml). Inhibits growth of H.sativum, V.albo-atrum and P.infestans.
Sequence:
PVSRQQCSQRIQGERFNQCRSQMQDGQLQSCCQELQNVEEQCQC
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MCSLADLNPRSTARGGLVAPPRCRKQPGKPERSRFQCSYCEYRSEYKCYVVAHERIHTGERPYKCPLCSKAFTFKHHVTTHLRCHTGEKPFRCSMCPRSFAQKSNLNQHLLIHRNNVR
The following text describes a protein:
Function:
Reduces the level of nuclear PKM isoform M2 which results in repression of cyclin CCND1 transcription and reduced cell growth; [Isoform TSC22D2-4]: May protect kidney cells from hyperosmotic stress.
Sequence:
MSKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATDYGPEEVCERSSSEETLNNVGDAETPGTVSPNLILDGQLAAASAAPANGGGGGVSARSVAGALAQTLAAAAASVSTPGPSSATPSQPPATCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSNTLEQTAERDSGLGATGGSVVVVVASMQGAHGLDSGTDSSLTAVSQLPPSEKMSQPTLAQPQSFSVGQPQPPPPVGGAVAPSSASLPPFPGAATGPQPMTAAVQPTQLQGAVAGGALPGPVGQGLPPPPNVNLAQPVALAAQPGPAGGSSLSQQFAYPQPQIPPGHLLPMQPSGQSEYLPPHVALQPPSPAQPLSTSASATSASAASFPLGSGQSVSSLGAQMMGASAQPSEAVAPGPVPVGQAAPCQPAGVAPAALGGVVQPGSGLTGVGQPQPVQPPQQMGGSGQLPAVPGGPHTVVPGVPNVPAAVPVPSVPSVPTTSVTMPNVPAPLGQSQQLSSHTPVSRSSSVIQQVGSPLAQGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQAPLSLIAESKPVVKPPVADALTNPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTCQESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSNNDQLSQLPAQQANPGSTSQQQAMIAQPPQPTQPPQQPNVSSA
The following text describes a protein:
Function:
Sterol glycosyltransferase responsible for the glycosylation of ergosterol to form ergosterol-glucoside.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MSFYKKVTRGLATPLQGSINLFSGSPNVSGDEGTDADNENPEHRTTYHSLSGRVNHDDDDEDVAKLEDIVGFFTGLLNTTTVCAGLGSLNNLKKHYLDEFIKKSALNPLRPQNYGPETSSKLNNNSIEELLNNGDTSLEKVRKMSLYDFDEHTSDSEEEDSADKEEESIAENLKPGKSGKARNHPRDSRTTATLITTQITRTKTATTATPTPTPTSSVDTDVTDVTEPIGKVTTKIPEEQLQGLNPLQKSVVKNLDPHHVREGVLIKVKNSETPLKNDRQELLEKIQLRLKIADKLQRVFDLSDEDTFCGNYSAWLIKDVLLQGHVYLTKDALLYFAFLPKRFSLENSSEVLDEDNSSSIVYSGNLGLKSAKYGEVVLNTVLQHRYWAVLRAETLSIYSSSTNLYFPVLVIDIKKCLYTEIIDKEKLNREAISPVNRGTYSPNGGLSGTATPRASTLENTASELNSMLSGDSYSPTEDNVETTASTVWFKLVTKKKTYKFSCDSSFSARQWCNNITKLIFQHNNANSNGEVLIKIPISKIAEYNKRALFSEEEEEDRTLDVTMNDIPLNVTIKYLGDNDNERKRDKLKRKYKGEEPTIEEVHFLFPKSGVEFFETFDKLVNPVVSDNDNQSSKSSITSTNFSEKAISTLSKSPNHLVQTVLDFNKPVDDDISAFKKFGTTITSPTRIFKATITSPEMTSIDETSLRDSFDSDRLHLPRDMSERALKNLEVSFVTSLKKLEDASKRYEKPHMEHSQTNLASILSDPSEVKKESKTAISKSIKALYSVGTHWSATPNHYFELGKYYVNKVQDRDSSQRNFQSHFSTNSKLLASYYGHLLRTVPVYGKIYVSETDVCFRSLLPGVSTKMVLPMTDIEEVRASRGSRLTYHGLRLIVRGSEELDLEFGSSKSRDDFQKVVLSVLERLHSKEGFRPEPYQWGSNFEVELYKTRMEYSDSENREIQQYDNSIDIKFAEKKIEMARVRMFEDRLMAASGLDVPIILEDSPFFKTELRPSTSYNITLLTIGSRGDVQPYIALGKGLVKEGHNVTIATHAEFGDWIKTFGLGFKEIAGDPAELMSFMVTHNSMSVGFLKNAQQKFRSWISKLLTTSWEACQGSDILIESPSAMSGIHIAEALGIPYFRAFTMPWTRTRAYPHAFFVPEQKKGGSYNYLTHVLFENIFWKGISGQVNKWRVEELDLPKTNLYRLQQTRVPFLYNVSPAILPPSVDFPDWIKVTGYWFLDEGSGDYKPPEELVQFMKKASRDKKKIVYIGFGSIVVKDAKSLTKAVVSAVRRADVRCILNKGWSDRLDNKDKNEIEIELPPEIYNSGTIPHDWLFPRIDAAVHHGGSGTTGATMRAGIPTIIKPFFGDQFFYATRIEDLGAGIALKKLTAKTLGDALVKATHDLKIIDKAKRVSQQIKHEHGVLSAIESIYSELEYSRNLILIKDIHNQNYKRHHPVPSGVQTPAYDTDSDDYDDDEDDDESDKDDEEEEEENSYDGYDGNGVNNSPSQNSSN