lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (polb), stabilizing polb thereby playing a role in base-excision repair (BER).
Subcellular Localization:
Cytoplasm.
Sequence:
MRPGEESQLVPKEIENAADEPRVLCIVQDTTNCKSVNERITLNLPASTSVKQLYEDVSNKAGYVSSTFSLMWGNGASNTDMAALDPTPDRTLQEAGFEAGKKNFLHLTDKDGEQPQLTSDESGTADSSGLDDSSQEKFIGPLPREESVAGTSNYVSQNYSYSSLLSKSDTGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVSSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINQLYQGKLKDYVKCLECGYESWRIDTFLDIPLVIRPYGSNTAFGSMEEALHAFIQPETLDGPNQYFCERCKRKCDARKGLKFLHFPYLLTLQLKRFDFDYTSMHRIKLNDRMTFPDELDMSPFIDMEDEKSPQTDSCTDSGAENEGSCHSDQMSNDFSTDDAVDEGICLETNSNIEKLNKSVAEKNSLYELFSVMVHSGSAAGGHYYACIKSFADGQWYSFNDQHVSRITQEDIKKTYGGATGNRGYYSSAFASSTNAYMLMYRLKNPARNAQFLEASEFPEHIKLLVQKEQEQEEQEKRQREIERNTCKLKLFCMHPVKQIMMESKLEVHKDKTMKEAVEIANKLMDLEGVIPLDCCRLVKYDEFHDYLERSYEDEEDRTMGYLLGGVKSSYMFDLLLETKRPDQVFQSYKPGEVMVKVYVVDLKTETVASPVSVRAYLSQTIIEFKQLISKSVDLPPDSMRVILERCYNDLRLLNVANKTLKAEGFFRSNKVFVESSDSLDHQLVFTDSHLWKLLDRHANTIKLYVSLPEHPRPTARSVGPKGGGDMNPQEDYCSRAKSVDAILEESTEKLKSLSLQQHQDGGNGDSSKSTEGSDFENIDSPLNEVDSSGSADNRELENRILPADPENNFQPEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADGTPIPLANGLDSHSITSSRRSKANDGKKETWDTAEEDSGTDSEYDESGKSRGEAQYMYFKAEPHAGEGCLAEGSKCLLVNVDKRITLAAFKQQLESFVGVPSSQFKVFRVYASNQEFESVRLNETLSSFSDDNKITIRLGRALKKGEYRVKIFQLLVNEPEPCKFVLDAVFSKGMTVRQSKEELLPLLREQCGLDLSIDRFRLRKKTWKNPGTVFLDSHVYENESISSCWEVLLEALDETEKMKSMSQLSLFTKRWRPSELKLDPFKEVVLESNSVEELRDKICEISAIPLENLEFAKGRGTFPCDISVLEIHQDLDWNPKVSTLNAWPLYISDDGAVIFYRDKTEEVMELTDEQRNELVKKESSRLQKTGHRVTYSPRKEKALKIYLDGPTNKDSAQD
The following text describes a protein:
Function:
May have a role in axon outgrowth and guidance.
Miscellaneous:
MISCELLANEOUS: This protein is translated by readthrough of a stop codon. Readthrough of the terminator codon TAG occurs between the codons for Arg-1631 and His-1633. There is currently no sequence that provides the identity of residue 1632.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MLYQLSKATTRIRLKRQKAVPQHRWLWSLAFLAAFTLKDVRCADLAISIPNNPGLDDGASYRLDYSPPFGYPEPNTTIASREIGDEIQFSRALPGTKYNFWLYYTNFTHHDWLTWTVTITTAPDPPSNLSVQVRSGKNAIILWSPPTQGSYTAFKIKVLGLSEASSSYNRTFQVNDNTFQHSVKELTPGATYQVQAYTIYDGKESVAYTSRNFTTKPNTPGKFIVWFRNETTLLVLWQPPYPAGIYTHYKVSIEPPDANDSVLYVEKEGEPPGPAQAAFKGLVPGRAYNISVQTMSEDEISLPTTAQYRTVPLRPLNVTFDRDFITSNSFRVLWEAPKGISEFDKYQVSVATTRRQSTVPRSNEPVAFFDFRDIAEPGKTFNVIVKTVSGKVTSWPATGDVTLRPLPVRNLRSINDDKTNTMIITWEADPASTQDEYRIVYHELETFNGDTSTLTTDRTRFTLESLLPGRNYSLSVQAVSKKMESNETSIFVVTRPSSPIIEDLKSIRMGLNISWKSDVNSKQEQYEVLYSRNGTSDLRTQKTKESRLVIKNLQPGAGYELKVFAVSHDLRSEPHAYFQAVYPNPPRNMTIETVRSNSVLVHWSPPESGEFTEYSIRYRTDSEQQWVRLPSVRSTEADITDMTKGEKYTIQVNTVSFGVESPVPQEVNTTVPPNPVSNIIQLVDSRNITLEWPKPEGRVESYILKWWPSDNPGRVQTKNVSENKSADDLSTVRVLIGELMPGVQYKFDIQTTSYGILSGITSLYPRTMPLIQSDVVVANGEKEDERDTITLSYTPTPQSSSKFDIYRFSLGDAEIRDKEKLANDTDRKVTFTGLVPGRLYNITVWTVSGGVASLPIQRQDRLYPEPITQLHATNITDTEISLRWDLPKGEYNDFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVVVRSGTESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFGPEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQIRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLDVQSYSVWLPYQAIDPYYPFENRSVEDFTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFYGDIKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLEGKENIVGPAREMHDNEGYEGQQVQLDENGDVVATIEGHLSHHDLQQAEAEAIDDENAAILHDDQQPLTSSFTGHHTHMPPTTSMSSFGGGGGGHTNVDAPDRXHSVVNQSDNNNSVVIVLVDNKPSSMICKDSKGGNIDVLESQQQQQQQQQQQPNQGGHNITTISAINGYNTLQHRRKSQLITFSSSSCDIKNSLSHEYINGSNGSAANGPPSSGSGSGSGPGSNRASRANVRLSFAEEDVMILPQNHSQQSNHQDDEVFTRRRSLLEVEIGVEVGEDGELAPHEMEEDLEEEDEDEELYMHDEFETHIDTKSNNANDDSGGGSYEDSHALHSSLGGSNRNSLEKDDDDIEVDVISTDVSCYDQLLGSSCNTRNGDDDDIATLVGDGDYSTTKLSKASRLSGAGVGGLVVSGGGGGTAIGGGIAVNGGGVLGNGVGSEAGGGIIYANPFMDDEGIAESGM
The following text describes a protein:
Function:
As part of the mitochondrial 3' processome (MPsome), involved in the maturation of guided RNA (gRNA) precursors.
Subcellular Localization:
Mitochondrion.
Sequence:
MRRLILSQTLRVAGRHRPPVAMFLQRFYRGHGISTALPLHYSKRHRKREGRMYGKPLRPVSDGENGASGDGGVLTRWEAVVSSRHQCESPVQTLAKSEKPKKAENTVAGKMTGSSRFSHRRDHSAYPSGVQPAPLATSGLPTQSSERQQQKQIGQQQVPLDALHRLFKVHAVMRTNYEALGKCTKVLKSFSTACAEALLQLGVLQKEQPSAMERKGFIDVQLCKSRVTEASKNGTSSPCFVLPPESPLYRTTIKFPTITVEHVLTTTVPAGCGAKDSGGDIMSVDMEGAAPFPMGHCESRPSTSAGNGVTVEYDCEGDVLSHGAAWNSIIEGFGQLALNLKQNASVSDFAQLAETLAYFKWVKDEEQVGWGTEDCVVKKFREAMANAKDTSASGSDPNTSDVSAALAAIAESFLRKIPRVDCIGSAVVHRGGERTAPSVHAIDVMLNLALRMCLSQWHAMSHFERMNIVLFCTYPWFAEDLSIAAGLCLTQSYLQSLLRADADVTYQHTFHYVRRVSRLCWPCIHDTDSAPVKKLLFPRDPQGTAVSSHALEAVSVEEKDNQLNQKEGLQGEEQATTTSESKLMWLPSFKDASCVSYGSSMKQRAAYELLLLWMTCVNPSGLHRSSPHGRYVSATGIAIIDVDLFVTQRFRTGKSKDEWLLLHPVEGDVVASVTIRTMVQHCETPYALTRLFFCNFHSVLPHIWGGIGARRREIIWTAWCRAVAQPLVNTLSGSDEGQREDDGGMQTLQITVDNADRTLDYLKPLISALTSDELFLRLIMRCADKSLEEMACEIGSGNNTLPLSKWCAQLAGFVYSVAFALHCRAKREGCNRDGGPSRPNTATDSANKKVVSGKQTDNLPKGTQEDISDLQLQFKAAVSALLRKLSAGDTQVAEQLLHHFYEPHFSGDQEREVVEDIQRHLQQVCDSQSRDALHAWIECSARASCEATVPLKEELLCKWQRTVLEADAGLPVVLPTIVECCRGLVGLVKKRGRNISGRRQGQQRGTESTTVGEESSCKEVFSKEELPVVITVLSRAMLTRTSTVSTVGLTKISSEISTLLSSCGYETADGNTSGGGRNGRELCDTNTATITSATAGERTVELELILSGEIDQKAGELPWITILEAVQLQLVPYTVVKNLLTSFKGGCDNGKERLRWQELQRDFQRKRHHRLVGNTLVFRWYGCAVPNDEGWEDGSGLMRPMAEDRDNVHSASHQGRTSTELGAFTRRLLKTLARAEVTRLDDRKEITTQTFVVGPSDDSATRHPTPGQEEDANLQRLDLLFRVHTLAAHILMTASTKKPHMIHELYDTLLHLVERVMPTTPNAPGNASDLLLLWLVGSAVAVGLRFRPNFLIKWPSTPEVSSGNLKSCPSAEEKTVHILRDIEPYLQSELLRPTVRLRFVINVLVALRSLELLGARIDVEGLHMDQLLVRASADRRLLSRHVNLFLIGCSALQSTQSSILHTALHLREAKYNLSFAEIERAFVAIALSADTFARQHEALMEQNYQQQQNRTLSVTVAANNTTPALRVSPVQLRHAWSALGRRVLENAGESPTDLFVRGLQCAAAVGCIDSALYQQLLSYVVEFRWEDLHILDWVMILRTVRQSFENRRNLEAYLKEPLQAFMLTMTDSGDNSTEQSVQKVNLKNHEGEQLLEGLCLFAEALPGLFIGDRELWGLLWQALGSQWSACFNAASNIEEQQRITAWLQEINASYAWAARAAGFRGLDEPTAL
The following text describes a protein:
Function:
Maternally-contributed central cell peptide regulating suspensor development and correct auxin distribution in early developing embryos.
Sequence:
MKSSHTTLICIIMLSLFALHECEKMEVKEIGRSSKIILPACMHETCSGGFSLKNDCWCCLRLKTKQARCWKEKEFPNAKELCFANCPPLE
The following text describes a protein:
Function:
Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
Subcellular Localization:
Cell inner membrane; Lipid-anchor; Periplasmic side.
Sequence:
MRLTRYFAISICTMVIGCQPQPTPKMVKIEGEAQGTTWHISFWSPNNINVKLVEDNINNRFDELDKNLSNYRPDSTISLFNSALSTEPIVVGEEIVELVAQAKIVSDKSLGCYDLTVKSLFDLWGFDKYQLMNPSAIAIAETLKDTGMQHIKIKSNSMAKDRAQVHVDLSSIAQGYSVGELAEILERYNIKNYLVEIGGEMVVKGYKPNGESWKVAIERPLPDKNILHKLLMIKQDQAIMTSGTYRHYFDNNGVRLSHILDARTGYPVTHNTVSVTVLHKNPMLADAWSTALLCLGHEKGIDIANENSINALFITDKNNELIEYSTNGFDLFTTSAVKSDGNKKH
The following text describes a protein:
Function:
Plays an important role in the control of DNA replication and the maintenance of replication fork stability.
Subcellular Localization:
Nucleus.
Sequence:
MQKSGGGAGSAPTGCFKCGRPGHWSRDCTLSPATTDPNLNVNDPSSVSKFGNKDGKNPLVGATELSGPKRGKQPRPKLTAEILMSDDGLGYVLRHFPRAFNYHGRGHEANDLGNLISLYAQWHSHLIPYYSFEQFITKVEQLGTTRHARMRLRELRERVADGGDPTKLHEPPTEQISDIDEQETEFSAKNEPITIPSEEAADTAMEDIFDADDMQDDVLEEIFRKATEETTQAGAESNRPHILENTAVSEESSRNSSYINVNCPAKIQITDEQRSRMEANRLKALQRAAAARAYASS
The following text describes a protein:
Function:
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
Miscellaneous:
MISCELLANEOUS: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MMFTKSTALALAAIVALSNVNAFSTSIHQPITSKAAHITSSSSLQAANNGLDTDTTLPSFSTKEEYTSYLQKAGRLPSGFAVGTAKGTFVSVEAPALGPLPIKATVIHLTEGPTDSWAAVFTKQSGCPVKVGKARLSGGHPLQALVINNKVSNVCPGGDGIAAAESVCAAVASSLNLPGGANSVLPSSTGVIGWRLPAKELAEDVAPRAIEALQTESAYAAAEAIMTTDRYPKLRSKTLSDGVRVVGVAKGAGMIEPNMATMLGYIMTDATIEKSKLQTMLTEACNRSFNSISVDGDESTSDTVVAIASGLKPLSSEDELKDALFEVCEGLSADLVRNGEGTGHVIRVTISNFPGSEYDARRMGRHLVNSPLVKCAISGNDPNTGRIAGAIGSFMGKFFPTESVAEMSLTLGGRTIFNNGQFVLEGDAVEKELSGHMSDAQLGEHDDFPKHQKFVEIGVDFGGSGSDVIVLGSDLTKEYVEVNADYRS
The following text describes a protein:
Function:
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Has an essential role in mediating growth by negatively regulating insulin signaling. It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae.
Subcellular Localization:
Nucleus.
Sequence:
MESDSPNPQQSGDSAPIPSGSNERDIASRRNRLMRITQRTIDTDESGRSSSSSSNSSFDAMEDNNNEVDGRVDRDDFSAHHSPSQQQQHGLNAEELPEDEAARLFENYIRERESAATEIYNTELPTEHAYLGKMERVEGVDYLEPGKTYRLPIYSHHSIVYPGEIVPLMLNDSTLYSGRSNDSSDGLKFGLVFQNQYRDGGRVYGVTCQVYERGAEGLSALMKTVAQQRFYIVRQSQERRADVKILPEIVLPDPLISTCSNAMVRYAHSSRKDRLSTFKRLLTQTTVWPQFVYDQYDTKEVMAKVERFLSSLNITSVQTDKVKLSFWLARNIPLTEEYRKMIFCTDSVLRRMLIINKALDHMWYFICKRCESEIANYDDMFAMSKQGVQTSYCNPAGYVHDTLTVHKTKENSTLPVERPSTNFSWFPGYSWQIIVCANCRQHLGWKFVAEKKNVLPKSFYGLSGTNITVKSHGDLKKTEGEFDLTARTASNEEQLDYEELSEFDSSTDEEMY
The following text describes a protein:
Function:
Catalyzes the adenylation of p-hydroxybenzoic acid (pHBA) to form p-hydroxybenzoic acid-AMP (pHBA-AMP), which is converted directly to p-hydroxybenzoyl-S-FadD22 (pHBA-S-FAdD22) thioester intermediate in a CoA-independent manner by attack of the phosphopantetheine thiol of FadD22. This intermediate primes the biosynthesis of the phenolphthiocerol (PPOL) by presenting the pHBA starter unit for elongation by Pks15/1. PPOL is an important intermediate in the biosynthesis of phenolic glycolipid (mycosid B).
Sequence:
MRNENVAGLLAERASEAGWTDQPAYYAPDVVTHGQIHDGAARLGAVLANRGLCRGDRVLLCMPDSPELVQVLLACLARGILAFLANPELHRDDHAFQERDTQAALVITSGPLCDRFAPSTVVDAADLFSEAARVGPADYEILGGDAAAYATYTSGTTGPPKAAIHRHCDVFAFVEAMCRNALRLTPADIGLSSARMYFAYGLGNSVWFPLATGSSAVVNPLPVGAEVAATLSARFEPSVLYGVPNFFARVVDACSADSFRSVRCVVSAGEALEVGLAERLTEFFGGIPILDGVGSTEVGQTFVSNTVDEWRPGSLGKVLPPYQIRVVAPDGAAAGPGVEGDLWVRGPSIAESYWNWPEPLLTDEGWLDTRDRVCIDDDGWVTYACRADDTEIVGAVNINPREIERLIVEEDAVAEVAVVGVKEATGASTLQAFLVPASAEGIDGSVMRDIHRRLLTRLSAFKVPHRFAVVERLPRTANGKLLRSALRGQTPAKPIWELASAEHRSGAPGQLDDQSASALVSGSREVSLKERLAALQQERHRLVLDAVCGETAKMLGEPDPRSVNRDLAFSELGFDSQMTVELCHRLAAATGLRVPETVGWDYGSISGLAQYLEAELSGADRRVTPQSARSGARALPLIEAQLNKVEELTAAIADGEKPRVAERLRALLGTITEGQEHWGQRIAAASTPDEIFQLIDSEFGES
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Part of the enzyme membrane arm which is embedded in the lipid bilayer and involved in proton translocation.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MELMKMTLYTTFMITIIALSLQQKHLMLALMCVETMMLIVFTMLVMFNSNSLTVSQTPMPIILLTISVCGAAVGLSLVVAITRTHGNDFLKNLNLL
The following text describes a protein:
Function:
Specifically deaminates adenosine-37 to inosine in tRNA-Ala.
Sequence:
MWQASPEADADFAERLGSLCLNFYRCKLKKSGKPQAGREWTVMAAIVKSEAVSLRGSQAKNEMTVVAMGTGSKCLGRNQIPADGGRVNDSHAEVLARRAFLRYLYHQLSLTKSDKKSIFCYNSEKRFYRLRDNVTFHLFISHTPCGDASIFPKGPESVGDKEFIDILECNSNIKRPIDKTENEGTVIGNSIYRSIPDVERGSVNKKLRTEDTESKRDDSFIETGLGNGILHYQAKLSKELRTWSDKFMDIYRTGAKCVPRAAQDPCLPGVNYHVLGVVRTKPGRGDPTLSTSCSDKIAKWNVLGLQGALLSHFIHPPIYLSSIIIASCPYSETALKRAVYDRILNINDLPQGYKVNEPLLLQISSVFEECKAEVIKRCNDRSSLQPSICSSGIIWCSDDTCQQQVVVDGRRQGFSKKNAASPKARCYICKYELFKSFLRAIKSTNADNIPRTLQDTELTTYIHYKIASAEYRRAREKFFERFPYWPRKPTSLESFSVDLADNVTSHNETV
The following text describes a protein:
Function:
Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
Subcellular Localization:
Nucleus.
Sequence:
MADKDKKKKESIFDLSKYIDKHIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFIQQQDG
The following text describes a protein:
Function:
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MEILNVFAGYPIITRTILIMIISLFVLMKVRIIHISQLSFDVDAILSGEIWRLVTPFLVYSDRFSIWFLFELLFISQALSQIEQTYRSWLHCLWVIFIGCSGILVLSFTFHFIGYVPGQLPLLFNSFSNFIIYLWSKQNREQRVVMFFIFVIPLVYFPWISLLLHVSFISEAINDIYGIFIGHVVYWLETVFPMYYNWKPLELPKFLYDLFIHPIHLEEEQNPNIELNEENQIEGQQLNEENQIEGQQLNENDE
The following text describes a protein:
Function:
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MSIEIRNVSKNFNAFKALDDINLDIQSGELVALLGPSGCGKTTLLRIIAGLETPDAGNIVFHGEDVSQHDVRDRNVGFVFQHYALFRHMTVFDNVAFGLRMKPKGERPGESAIKAKVHELLNMVQLDWLADRYPEQLSGGQRQRIALARALAVEPKILLLDEPFGALDAKVRKELRRWLARLHEEINLTSVFVTHDQEEAMEVADRIVVMNKGVIEQIGSPGEVYENPASDFVYHFLGDSNRLQLGNDQHLLFRPHEVSLSRSAVAEHRAAEVRDIRPLGAITRVTLKVDGQDELIEAEVVKDHDSLAGLARGETLYFKPKAFQPVANL
The following text describes a protein:
Function:
Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.
Subcellular Localization:
Endosome membrane; Multi-pass membrane protein.
Sequence:
MEIATRRSRVVLEVAVLSLICGVSLVFAGDIVHQDDIAPKRPGCDNNFVLVKVPTWIGDTEEEEFVGVGARFGPTLESKEKDATKSRVTLSDPPDCCSTPKNKLTGEVILVHRGNCSFTAKAHVAEAAGASAILIINNQTQLFKMVCEADETDVDIGIPAVMLPQDAGASLKESLENKLNISVQLYSPRRPLVDVAEVFLWLMAVGTILCASYWSAWSAREAAIEQDKILKVLTFYHLRTNSQIFTRVDETYNLILILINNNNNVVESWQDASDEYLNTESCRSSAVVDINTTSAVLFVVIASCFLVMLYKLMSYWFIEVLVVLFAIGGVEVVCKHVWWPCYHDSAETFVKVPFLGGVSYLTLAVSPFCVVFAVVWAVYRRISFAWIGQDILGIALIITVIQIIRVPNLKVGTVLLCCAFMYDIFWVFVSKWWFHESVMIMVARGDKSGEDGIPMLLKIPRMFDPWGGYSIIGFGDIILPGLLVAFSLRYDWLSNKSLRAGYFLWVMIAYGLGLLITYIALNLMDGHGQPALLYIVPFTVGTLLTLGKYRGDLRHLWSKGEPDRLCPHVQLQHEEQ
The following text describes a protein:
Function:
Probably part of the binding-protein-dependent transport system YphDEF.
Subcellular Localization:
Periplasm.
Sequence:
MPTKMRTTRNLLLMATLLGSALFARAAEKEMTIGAIYLDTQGYYAGVRQGVQDAAKDSSVQVQLIETNAQGDISKESTFVDTLVARNVDAIILSAVSENGSSRTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKIDQPKIAVINCEAFEVCVQRRKGFEEVLKSRVPGAQIVANQEGTVLDKAISVGEKLIISTPDLNAIMGESGGATLGAVKAVRNQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDISGKKMGNAVFAQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLATHVDGLP
The following text describes a protein:
Function:
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
Sequence:
MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNRFREIIQDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITGSILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGQLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPSDFVENYDKYLPTAMLSKAVYADTEGFISAMDTRALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDSIDGQRPLAVIHAKDEASWQEAAKAVKAAIILDDKAPASTPSVYRRITE
The following text describes a protein:
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein.
Sequence:
MINCLLIFLLLPITKTSAAKFESTEGRLANYLLNGYNPQFRPYNKKYENKTFVDVMMTLSQIISVKEKSQEFTTSVYMQYDWLDDRFGWVPDDYDGITTVRIPCASIWVPRIVLQNSIDGNFDVSLRTNALIQHDGKVSWLPPALYKSTCTIEVALFPFDWQNCTMVFRSATYDRTEMEFGIPIDTVYIDLSAFQSNGEWDILQRPVKINSNENDKTYQDITFYFIIRRKPQFYIINLIIPCILMSSLSCFVFYLPSISCEKMTLSISILLGETVFLFLIAQRMPETSLAVPLIAGYLLFVMILVIISVICSVVVCNVHYRSNTTHSMPDWIVWIFMEKLAPLLKVERPSEEESGACSARPRRCSSVSTRKAMKQRSEWKPPSEILFDHQASRLGFRARHYLNEYGMTGINVAAPENGSFVPPSFKKLPKGFQPAADSIDYIANQKKEENEMGQSQDDWGYVALILDRLLLWVYLATFTLGTLFFFLQTKFAYYPEKLN
The following text describes a protein:
Function:
Plays a role in type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. Substrates include proteins required for biogenesis of the type II general secretory apparatus.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MIYFTMFLLGGILGIALWFYLSGFITRLQQNIYAIYVELFPQNRSPFQPHFASIQQKKCGHILRYFFSIGVGFIFLQIAFKDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGADNNFSLLTLSESIKSAASFFIVFYVIYWLAKFYYGKEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHRKKKEFLPFAPFMNLSAVIIYFVKYYGY
The following text describes a protein:
Function:
May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Cell projection, neuron projection.
Sequence:
MTSCSNTCGSRRAQADTEGGYQQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSSVFWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFMVVDTHAVKYNGALDTCKLAGAVLFCIGGTSMAGCLLMSVFAKSYSKEEKFLQQKFKERIADIKAHTQPITKAPGPGDTKIPVTLSRVQNVQPLSAT
The following text describes a protein:
Function:
Required for utilization of free heme at low concentrations.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MRFSKLSLAITTTLVTANALAQSVELDSINVIATRDPSRFAYTPEKQSKDSLLSKQATSVADALEDIPNVDVRGGSRSIAQKPNIRGLSDNRVVQVIDGVRQNFDLAHRGSYFLPMSLIQEIEVIKGPSSSLWGSGALGGVVAMRTPNALDLLKNNDKFGVKIRQGYQTANNLSEKDVSVFAANDKFDVLISGFYNNADNLRTGKGNKLNNTAYKQFGGLAKFGWQINDANRVELSHRETRFKQTAPSNNEVENELTNEQITDQIKKFHGQKDDLLPPTTQPSPSERSEFYSKVKTRLGSVSYLTDQQIPDQSTVFNYYLTPDNPYLNTHIALYNNKTIEKEQRKVSGVKDQTKLTTRGINLRNSSELSHISFVYGVDYMRDKIRTERGTNGSDAKFRADPYNANSNTTGVYLIAHIPLFGEKLLVSPSVRYDHYDTSSKTVKYKDNHLSPATKLTWIVTNWLDFTAKYNEAFRAPSMQERFVSGAHFGANTLGLDHINRFVANPNLRPETAKNKEITANLHFDSLFKQGDKFKIEATYFRNDVKDFINLKIFNDAKTSASAGANPNTNGALLPKNSQYQNITNARLSGIELQAQYQTERLTLFTNYGSTKGKDKDSGEALSNIAASKIGVGVNYALVKDKFTVGATVTHYAAQRRVPKDHSVTYPSYILTDLRATYAPLKGEWKNLRLDFALENLFDRKYQPAFSLMEGTGRNAKISAVYSF
The following text describes a protein:
Function:
Multifunctional transporter with an impact in cell morphology and differentiation. In the presence of borate B(OH)4(-), acts as a voltage-dependent electrogenic Na(+)-coupled B(OH)4(-) cotransporter controlling boron homeostasis (By similarity). At early stages of stem cell differentiation, participates in synergy with ITGA5-ITGB1 and ITGAV-ITGB3 integrins and BMPR1A to promote cell adhesion and contractility that drives differentiation toward osteogenic commitment while inhibiting adipogenesis. In the absence of B(OH)4(-), acts as a Na(+)-coupled OH(-) or H(+) permeable channel with implications in cellular redox balance. Regulates the oxidative stress response in corneal endothelium by enhancing antioxidant defenses and protecting cells from reactive oxygen species. In response to hypo-osmotic challenge, also acts as water permeable channel at the basolateral cell membrane of corneal endothelial cells and facilitates transendothelial fluid reabsorption in the aqueous humor. In the presence of ammonia, acts as an electrogenic NH3/H(+) cotransporter and may play a role in ammonia transport and reabsorption in renal Henle's loop epithelium (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Sequence:
MSQNEHCQDSGEYFSAGTQGYFKNNMEDNLEVREDSLGDEVFDTVNSSIVSGESIRFFVNVNLEVQPSKSDLEAATGGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAQASIILNETATSLDDVLRTMLNRFALDPNHAEPDCDLDLLMAKLFTDAGAPMESKVHLLSDTIQGVTATVRGVQYEQSWLCIICTMKTLQKRHVCISRLVRPQNWGENSCEVRFVILVLAPPKMKSTKTAMEVARTFATMFSDITFRQKLLKTRTEEEFKEALVHQRQLLTMMMPRAAGHSMSSLHTHRHPQPPKCKDFFPFGKGIWMDIMRRFPVYPMDFTDGIIGKSKSVGKYVTTTLFLYFACLLPTIAFGSLNDENTNGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLAIYTQVIRVICDDYNLDFNAFYAWTGLWNSFFLALYAFLNLSLLMNLFKRSTEEIIALFISITFVLDAVKGMVKIFGKYYYGHHYHTKRTSSLVSLLGIGRSPNSSLHTALNASLLASPVEMATTSSPGSTHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVRETLSDCALPIAVLSFSLIGSYGFQEIEMSKFRYNPSESLFEVAQIHSLSFKAIGSAMGLGFLLSLLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYETIVDVKETRLTALGASVLVGLSLLLLPFPLQWIPKPVLYGLFLYIALTSLDGNQLFSRVALLLKEQTSYPPTHYIRRVPQRKIHYFTGLQILQLLLLCAFGMSSLPYMKMVFPLIMIAMIPIRYNLLPRIIEAKYLDVMDAEHRP
The following text describes a protein:
Function:
Putative acid-stable proteinase inhibitor.
Subcellular Localization:
Secreted.
Sequence:
MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPARGTAPGCPGQANSDLGSVALHLSWGPTERVHDGRPGALPAGQHYLYQRWFQPSDNHWPADTSLQPIHPWFLLLGVKVHSLSSEEGLCITPVLCTTAIRASHPS
The following text describes a protein:
Function:
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MAAEDTSVSGVSGRYATALFELARDQKAVDEVKADLDRFEALLGESADLKRLVRSPVFAADAQSRALTAVLDKVGIAGISANFLKVLTANRRLFVVADVIRAYRALVAKFKGEATADVTVAEALSDKNLDALKVALKSVTGKDVALNVKVDPSIIGGLVVKLGSRMVDGSLRTKLNSIKHAMKEAG
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MADHWGYDKHNGPDKWGESYPIANGSRQSPIDIKSSTTTYDEKLTPLKLKYDPSTSLDIQNNGHSFQVSFVDDQNSSTLTGGPVTGTFRLKQFHFHWGSADDKGSEHTVNGKCYPAELHLVHWNTKYPSFKDAVDKPDGLAVVGIFLKIGADNPKLQKILDAMDAIKSKGKQTPFPNFDPSVLLPSSLDYWTYLGSLTTPPLLESVTWIVCKQSISVSSAQMKRFRSLLFSGDGEKACCMVNNYRPPQPLKGRVVRASFK
The following text describes a protein:
Function:
D-arabinono-1,4-lactone oxidase that catalyzes the final step of biosynthesis of D-erythroascorbic acid, an important antioxidant and one of the virulence factors enhancing the pathogenicity. Is also able to oxidize L-galactono-1,4-lactone, L-xylono-1,4-lactone and L-gulono-1,4-lactone.
Sequence:
MTDIPESLKPFVTKKVIHSTWAGTFLCKPQAIFQPRNVEEIQELIKQARLHGKTIMTVGSGHSPSDLTMTTEWLCNLDKFNHVLLEEPYYAPKSPTDDTPEIKFVDLTVEAGTRIFELNEYLKRNNLAIQNLGSISDQSIAGLISTGTHGSTQYHGLVSQQVVSVKFLNSAGELITCSSVDKPEYFRAILLSLGKIGIITHVTLRTCPKYTIKSKQEIINFETLLNNWDNLWLESEFIRIWWFPYTNKCVLWRANKSTDPLSDPRPSWYGTKLGRFFYESLLWVSVHLFPRLTPFVEKFVFGQQYGEVETLGKGDIAVQNSVEGLNMDCLFSQFVNEWSSPLNSGPEILTELKKIITDASQTGDFFVHAPIEVRCSNVTYSDEPFTDDKNQKSLYPSQEWLSNRSKTSAGPIPGNNLRPYLDNSPKLPYSKDGKITNDQLTLFINATMYRPFGTNVETHKWFQLFEDVMSKAGGKPHWAKNFIGLTQDEKYDKQQDLKTQLEFGGKPFYTMLGFKPVMQDWFGKDLVAFNKVRKETDPDGVFLSGKVWAERNGILLD
The following text describes a protein:
Function:
Putative gamma-glutamylcyclotransferase.
Sequence:
MMMVADGRQAGHPLRAWVHRARLKMVCYKWDGPGQSQLDWRHTHHQPPPPPRGSSSSSDQIFIRSIRTATGRRQSSMGAAGDPAPLVFTYGTLKRGFSNHRLLEELSASGDATLVGPAVTSARLPLVCGPYRVPFLLNLPVPAVAAAHRVRGEAYAVTPRGLARLDELEGVATGHYERLPVQVEVEVEGEGEGGTRVVEAIAYFAHRSYAGDLWRRSGEEGVPEYTHGVAAGYVRRKDRPQGQTFLDQIRVFVSS
The following text describes a protein:
Function:
Involved in the assembly of the cytochrome oxidase complex. Required for the maturation and subsequent assembly of the mitochondrially encoded cox2, the precursor of subunit 2 of cytochrome oxidase (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSTPNEPEKPGIIDAFKSLKMSDFAHMVHHPCFKESLITSVVCGLGVGCIHLFLRAPISRAANWGFGTYFGMSIVSWEGCNYRKQLETNNFNIKITEAAEKTPKHRSSRSAQEIDEGFNE