lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Multifunctional protein that may modulate protein degradation pathways, apoptosis, transcription, signal transduction, cell cycle progress, and genetic stability by directly or indirectly interacting with host factors; Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC). Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation. This host complex would otherwise bind to viral episomal DNA, and prevents its transcription. Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
Subcellular Localization:
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Sequence:
MAARLCCQLDPARDVLCLRPVGAESRGRPLPGPLGALPPASPPVVPTDHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHRNLPKVLHKRTLGLSAMSTTDLEAYFKDCVFTEWEELGEEVRLKVFVLGGCRHKLVCSPAPCNFFTSA
The following text describes a protein:
Function:
Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Cytoplasm, cytosol. Endoplasmic reticulum. Mitochondrion inner membrane; Peripheral membrane protein. Nucleus membrane; Peripheral membrane protein. Secreted, extracellular space, extracellular matrix.
Sequence:
MRSLGALLLLLTACLAVRASPVPTPPADIQVQENFDLSRIYGKWFLVAMGSTCPWLKKIKDRMTISTLVLGEGATDGEISTTSTRWRKGVCEEISGTYEKTDTKGKFRYHKSKWNLSIESYVVQTNYDEYAIFLSKKFSRRHGPTITAKLYGRDRQLRESLLDTFREVALGVGIPGDSIVTLADRGECVPGEQEPEPMPFSRARRAVLPQEEEGSAAGQLTPEFSKKEDSCQLDHAEGPCLGMISRYFYNGTSMACETFQYGGCLGNGNNFASEKECLQTCRTVAACNLPIVQGPCRAFIRLWAFDAAQGKCVLFTYGGCRGNGNKFYSEKECKEYCGIPGDGDEELLRFSG
The following text describes a protein:
Function:
May act as a scaffold to regulate the recruitment and assembly of spindle midzone components.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle. Midbody. Note=During early anaphase, localizes along overlapping interpolar microtubules between the separating chromosomes. During late anaphase, localizes to the center of spindle midzone. Concentrated at the midbody during telophase.
Sequence:
MGSKTSKMCCPQLRKKKRQKAHKEGPSSQELNDLNAKSQGPNELLQKIKEYEQEIRNILQKHQEEKTALADAHKADVEARTLVLQAQAQKDRDAETVKLLSEQAATMKAEMEEMFAELQKSYEQEKSSLTEIHQQLTDALQESVDELNSQLASFREKMKRVEESILSQDYQRHIQDYGSPGQFWEKELQSLHFVIEMKSELIREQDKRLQRHKSTMERSLELEERSRTLQQENEALKVQTQKQGAITVRLSEELLSIQTTLEKQTHRCEQLEREKEQNLYRAVIGDITQQFSLQELPVMVL
The following text describes a protein:
Function:
Oxygenase component of a two-component system that degrades 2,4,5-trichlorophenol. Uses FADH(2) supplied by TftC to oxidize 2,4,5-trichlorophenol (2,4,5-TCP) to 2,5-dichloro-p-benzoquinone, which is chemically reduced to 2,5-dichloro-p-hydroquinone (2,5-DiCHQ). Then, TftD oxidizes the latter to 5-chloro-2-hydroxy-p-benzoquinone.
Sequence:
MRTGKQYLESLNDGRVVWVGNEKIDNVATHPLTRDYAERVAQFYDLHHRPDLQDVLTFVDADGVRRSRQWQDPKDAAGLRVKRKYHETILREIAAGSYGRLPDAHNYTFTTYADDPEVWEKQSIGAEGRNLTQNIHNFLKLLREKDLNCPLNFVDPQTDRSSDAAQARSPNLRIVEKTDDGIIVNGVKAVGTGIAFGDYMHIGCLYRPGIPGEQVIFAAIPTNTPGVTVFCRESTVKNDPAEHPLASQGDELDSTTVFDNVFIPWEQVFHIGNPEHAKLYPQRIFDWVHYHILIRQVLRAELIVGLAILITEHIGTSKLPTVSARVAKLVAFHLAMQAHLIASEETGFHTKGGRYKPNPLIYDFGRAHFLQNQMSVMYELLDLAGRSSLMIPSEGQWDDSQSGQWFVKLNNGPKGNPRERVQIGRVIRDLYLTDWGGRQFMFENFNGTPLFAVFAATMTRDDMSAAGTYGKFASQVCGIEFGGAEPTAYAATADYAKALDKGLAPEPAAAESATS
The following text describes a protein:
Function:
Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm. Required for the nuclear import of the complex composed the large subunit (TOA1) and the small subunit (TOA2) of the general transcription factor IIA (TFIIA). Required for the nuclear import of the RNR2-RNR4 heterodimer, also called beta-beta' subunit, which corresponds to the small subunit of the ribonucleotide reductase (RNR). May play a role in regulation of pleiotropic drug resistance.
Miscellaneous:
MISCELLANEOUS: Present with 9760 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus envelope.
Sequence:
MSSIHEVVALIEELYSPHPKHDVNQIQQSLQSIQKSEQGFHLANELLSDDKYSANVKYFGALTLTVQLNTRGENDYETLWNVFRSNLLYLTKFSTLYVSNPNMYGQSLIIIKKLMSNLSLIFTKINDPQLNNAGNENMIKQWNNPINTFIQLMSVQNQNINADQLLLDSINCSLTYEQLSQFVSLSQKHNELALTFTEVIVEDLTKFQTKRHSMSQIHEVVHEHLYISTMALINLNLTAQAVFNPTVFDCITAWINYISLTRSVSSSGRMDLSEIFQNLIDLMYQSTEGSDGYENAEKILTIFGNVFANDPLLMSYDLRQQIECIFLGVVRPDSGITDISNKNSWMLQYMNYLVTNDFFSELKELAICIVDFLQINTLSVCNKLFTNIQAADNGQVQDEYIQEYIKVLLQMTNFPLTPVLQEFFSVRMVDFWLDLSDAYTNLASETLRPNSIELSTQIFQQLINIYLPKISLSVKQRIIEEEGESTSVNEFEDFRNAVSDLAQSLWSILGNDNLTNVLIDGMGQMPAASDETLIIKDTDVLFRIETMCFVLNTILVDMTLSESPWIKNIVDANKFFNQNVISVFQTGFQTSASTKVSQILKLDFVRTSTTLIGTLAGYFKQEPFQLNPYVEALFQGLHTCTNFTSKNEQEKISNDKLEVMVIKTVSTLCETCREELTPYLMHFISFLNTVIMPDSNVSHFTRTKLVRSIGYVVQCQVSNGPEEQAKYILQLTNLLSGSIEHCLASSVQLQEQQDYINCLLYCISELATSLIQPTEIIENDALLQRLSEFQSFWSSDPLQIRSKIMCTIDKVLDNSIYCKNSAFVEIGCLIVGKGLNLPDGEPYFLKYNMSEVMNFVLRHVPNCELATCLPYFVYLLEKLISEFRKELTPQEFDFMFEKILLVYYDAYIINDPDLLQMTIGFVNNVLDVKPGLAIGSKHWTSFILPQFLKLIPSREKFTIVAVAKFWTKLINNKKYNQEELTTVRQQVSSIGGDLVYQIMYGLFHTQRSDLNSYTDLLRALVAKFPIEAREWLVAVLPQICNNPAGHEKFINKLLITRGSRAAGNVILQWWLDCTTLPNYQG
The following text describes a protein:
Function:
Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MAASERLYELWLLYYAQKDLGYLQQWLKAFVGAFKKSISLSSLEPRRPEEAGAEVPLLPLDELHVLAEQLHQADLEQALLLLKLFIILCRNLENIEAGRGQVLVPRVLALLTKLVAELKGCPPPQGQGTQLENVALHALLLCEGLFDPYQTWRRQRSGEVISSKEKSKYKFPPAALPQEFSAFFQESLQNADHLPPVLLLRLIHLFCAVLAGGKENGQMAVSDGSVKGLLSVVRGWSRGPAPDPCLVPLALEALVGAVHVLHASRAPPRGPELRALLESYFHVLNADWPAGLSSGPEEALVTLRVSMLDAIPMMLACEDRPVLQATFLSNNCFEHLTRLIQNSKLYLQSRAPPEGDSDLATRLLTEPDVQKVLDQDTDAIAVHVVRVLTCIMSDSPSAKEVFKERIGYPHLQEVLQSHGPPTHRLLQELLNMAVEGDHSMCPPPPIRNEQPVLVLAQWLPSLPTAELRLFLAQRLRWLCDSCPASRATCVQAGLVGCLLDTLSTGLALEARCQEQLLALLQALGRVSIRPMELRHLLRPPPGLDSEPGRAEAGKARHAGAVIRALSGMARHQGPARALRYFDLTPSMAGIMVPPVQRWPGPGFTFHAWLCLHPMDTAPTPAPTRPLQRKQLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYLTMSLPEVSFADSAWHCVAIVHVPGRRPFSQNLVHVYKDGHLVKTAPLRCPSLSEPFSSCCIGSAGYRTTTTTTGLPTPPVPATLAYTHPALTRSQSVPASTGLGWGSGLVAPLQEGSIDSTLAGTQDTRWGSPTSLEGELGAVAIFHEALQATALRTLCTLGPNETAPFKPEGELHELSTRLLLHYSPQACKNNICLDLSPSHGLDGRLTGHRVETWDVKDVVNCVGGMGALLPLLERVAAQPKEAEAGPTETHDLVGPELTSGHNTQGLVLPLGKSSEERMERNAVAAFLLMLRNFLQGHMVNQESLVQCQGPAIIGALLRKVPSWAMDMNVLMSAQLLMEQVAAEGSGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSIVREHRQKLRKKYGVQFILDALRTHYSPQRERPLAADDLRTVQTSLLGLAREFLVRSLSADDVQVTQTMLSFLAATGDDGQVVGALDLLLALLHGSLAQESLAVFLLEPGNLEVLLALLVRPGSLPLLPDRVCKILRRLQQNERLPERSRQRLRLRECGLQGLVACLPEGTVSPQLCQGLYKLFLGADCLNLSDLLAVVQLSLQADLSVRLDICRQLFHLIYGQPDVVRLLARQAGWQDVLTRLYVLEAATAGSPPPSSPESPTSPKPAPPKPPTESPAEPSDVFLPSEAPCPDPDGFYHALSPFCTPFDLGLERSSVGSGNTAGGGGSSGTLTPASQPGTPSPLDGPRPFPAASGRHSSSLSNVLEDGSLPEPTISGDDTSNTSNPQQTSEEELCNLLTNVLFSVTWRGVEGSDEAAWRERGQVFSVLTQLGASATLVRPPDCIKRSLLEMMLESALTDIKEAPVGVLASLTQQALWLLRLLQDFLCAEGHGNQELWSEKLFEGVCSLLDRLGAWPHLANGTADLREMAQIGLRLVLGYILLEDPQLHAQAYVRLHMLLQTAVPARREEACYVLSKLEAALGRALNTSSSESATDEAGSPPAAAAAAERCSWLVPLVRTLLDRAYEPLGLQWGLPSLPPTNGSPTFFEDFQAFCATPEWRHFIDKQVQPTMSQFEMDTYAKSHDLMSGFWNACYDMLMSSGQRRQRERAQSRRAFQELVLEPAQRRARLEGLRYTAVLKQQATQHSMALLHWGALWRQLASPCGAWALRDTPTPRWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEVPLTPTEEASLPLAVTKEAKVSTPPEELQEDQLGEDELAELETPMEAAELDEQREKLVLSAECQLVTVVAVVPGLLEVTTQNVYFYDGSTERVETEEGIGYDFRRPLAQLREVHLRRFNLRRSALELFFIDQANYFLNFPCKVGTTPVSSPSQTPRPQPGPIPPHTQVRNQVYSWLLRLRPPSQGYLSSRSPQEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEPHPTRLSAEEAAHRLARLDTNSPSIFQHLDELKAFFAEVVSDGVPLVLALVPHRQPHSFITQGSPDLLVTVSASGLLGTHSWLPYDRNISNYFSFSKDPTMGSHKTQRLLSGPWVPGSGVSGQALAVAPDGKLLFSGGHWDGSLRVTALPRGKLLSQLSRHLDVVTCLALDTCGIYLISGSRDTTCMVWRLLHQGGLSVGLAPKPVQVLYGHGAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLGATFPGPIFHLALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLRASLPLAEQPTALTVTEDFVLLGTAQCALHILQLNTLLPAAPPLPMKVAIRSVAVTKERSHVLVGLEDGKLIVVVAGQPSEVRSSQFARKLWRSSRRISQVSSGETEYNPAEAR
The following text describes a protein:
Function:
Protein kinase that functions as a regulator in the pheromone-induced mating pathway downstream of mitogen-activated protein kinase (MAPK) FUS3. Diminishes transcriptional induction of genes in response to pheromone signaling.
Sequence:
MSLSRILRYNQRNNKTTASLTAEHAYSDNWAYSVSLGDPTSVGVNMAAKTGEALNKSYDSVFSSLPVADSVPRTDFTASSRDDENTDVQKLTTSWMEKIDTKMPENISKIDSNIISSPMVSKVEARFIVPKGRLRKNSTDFTSSFSNSLSLPKSYGKLIFFTSKKNSSSTKKNLANDISDNKHNNNSSNTIGHNIPVTTATATCDEIACTSTEHEYNVYEEERMFTTRVYSLEDSVSSLSTNPLDDTYSEAVQVNTRHIEDTESTAHIRKHSYTTSLSSIKRLFKITSFSNNNSNSCDHQESTVADDCAISSSLKETTSSPVSTGSFSLMIENEDSDRDQIIQALYSNIEASTDLVSRKYRDLDVVLGEGSGGKVKLVQRVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQILEYCEYDLFSLVMSEKMHYEEICCLFKQLINGVKYLHDIGLSHRDLKLDNCVVTRRGILKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRFPWKYPKVKDVQFKAFCSGRGVSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLPEETHKIMRRILEVSPFRRITINGILQDGWIKEIETCQVVGAASPNEASLRIINKGNHIHTNIDQRYAHIGGLHQRT
The following text describes a protein:
Function:
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
Sequence:
MAAKIRQNDEVIVLAGKDKGKKGKVTKVLATGKVIVEGINLVKKHQKPVPAMGVQGGIVEQEAAIDVSNIAIFNAKTGKADRIGFRFEDGKKVRFFKSNNEIVSN
The following text describes a protein:
Function:
Required for assembly of cytochrome c oxidase (complex IV).
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MPLVPKSSYYDKNYKQSAALIRARRPYLVKNALTGAGIFAFALGVFAFTIRAVSQDEFEDVKVPAAPTKRDS
The following text describes a protein:
Function:
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MKRFMQIWKPAVIGFLLLTLVCGVLYPGVVTVFAGVAFHDKANGSIIEEKLADGTTGKVGSAEIGQTFTEPEYLIGRAASDGVATNLNPTSEEQKQLVEKRIAWWHKLDPTNNRVIPMDLVTASASGVDPDISEAAAAYQVDRISRERGISTKEVKEIIAEHTSNRLLGFWGEPTVNVLQVNLALDRLKM
The following text describes a protein:
Function:
May be involved in the processing or stability of mitochondrial mRNAs.
Miscellaneous:
MISCELLANEOUS: Present with 2080 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MIRLAQQTQVLKGKPPNQFVPHPTKNSLTHPMKFNGTIAMEHHEHNYAIPYTPATFNNPALATYQVSPANHFVPHFGGNIGANNNNHLAQNNSNNSNNHHNNNRNHHHNNNRNHHQNNHNHSKYNNSNQGNSISPDSPWFHKVCAFEDCVSQTLYMSQTPRRQNMKHHSEHPNSNANPLFWDSIGRAMGLYHDLLTTPELNSDRVSKLVHLLHNGLRANRNQLTRMNKKPDYDSQSFHKEMTNYLCKSLREISEDVLNGKVELNEYGAMHLITAFKELLLFEEAVDIWKAAINGQNTYTSNIFLNPRVVGVILPILYDNGVSYPEIQALYEKSSSMINYFHPNLSVGMIRASLSASENDMALKLFQKLCQESTEMKYGYLIETHLSFIGECKDLNVAQTFFDKALNDEMPYKIDLQVSYVKSFLRNIWSQTRDFNHIYQIWYKSSLHYGRNVNHGISSSLNDTFFDIFFENYAVDKMQGFQTLQNIIQTYNNIKHIDEPFFNIILAKCTVWHDRSILEYIDKSYEAYHIPKTIVAYRILLKSMGSVDDASNAEILQRWMDLIRKSDEIGQRFIANADWAALRDATVTWTQNDRDSKKSNMNSTQISRTATPSPSLTPMDTPAPEHLFNNPQNPMDFYSHPALQAATASGAFDEFAAEAASSSIPVDGRMVLYLKIVKRYSPYCRDSRQLARLTTGTAVKYSVLQEVLNQFQTLIVNDIPIPELHNLKPTCV
The following text describes a protein:
Function:
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSDANPVNQELETFNKQKLKKTNTQEKNHLPTQAGRSKEGTHKKNNLPAPFYPFFFFLSRPIYSIFLCVAMISKK
The following text describes a protein:
Function:
Part of the iron transporter system efeUOB/M involved in iron import (Probable). Mediates the uptake of Fe(3+) ions, delivered by EfeM, across the cell membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MARGLALILFSLLMVFGSAAHAEDDPIAALIQLNKQMIKSVKDGDMDSAQQTFDTFKAKWKKEEPSIKKENLSSHSEMDANIAMISLSFINQDARKLKTQLEELASHLETYQQAVVLKKTSSGQSRASLTAYIQSLKDTKQFIEKKQLDEASSAIDNLVTSWLAVEGDVVSQSKEAYTTSEENLALMKAEIGSHPEKVSKQIDEMIQLLEPIASSSYSWWDAALIPVREGMEALLVIGALLTMTKKARVTRSSTWIWGGASAGMAVSLAAGIGVTVLFSSSVFGENNFLLGGVTGVLSAVMLLYVGVWLHRNASMDKWREKINIQKSQALKKRSLLSFALIAFLAVVREGLETVIFFIGLVGKLPLTELIGGTAAGLIVLVIVGVLMIKLGMRIPLKPFFLLSMAVVLYMCVKFLGTGVHSLQLAGILPSDAESWLPSVSVLGIYPSVYSTIPQMLILLFLLIALVSEAAKHFTNGKELTK
The following text describes a protein:
Function:
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Subcellular Localization:
Nucleus.
Sequence:
MPKYYCEYCDKYLTHDSPSVRKSHTIGKVHQQAVTLYYKQFEAEWFKSQMQQKGGQVPMMPPFGMQPGLLPPNMVPGQFNIPMMPPGQFPFPPPPGQPMGGMPPHQQQPMSFNPHHPYPPPHLQQSAQQFNSNSPPSNNDQ
The following text describes a protein:
Function:
As part of AP-5, a probable fifth adaptor protein complex, it may be involved in endosomal transport.
Sequence:
MAERNSASWNRKVASFCSEPKTFLCDSSVDGFLGELLKDLQSEAIHGQTKILMMDLLLEFPEFLCPDQKTVEMTAETLMNILKKMPSSERSMTLRCHLLLAIETVLITCESFNQNSKMAQDFASLLMHIISDVNDKKQGVANRPLRTTACECLRELESCYPGFLSQRMEKLYLMQQQEVTAAHQSYTLLYTVVLKNAIRFLAQKEGPSNGALKNALLSNEDFFWSATENMVELQPSSNEQLLLLPSNSETKDLKSILALLLEDSYLLTPVCQNTLFWQIVQVVAMARTISPVIFKSQLVRLFSTMDLSCFHSILQMKAVFTDSLFTGEDEHFLIQRLVGMTQHPLLSTPVKLFYLDCLLHFPENRPLTSNSEENLPVLLTVQMTSSLFPNVFNDHSTMLCRQNVLSMVYLENEGSYSEKGIAFLFEHVMSLYSMVHKNGNREITATFFRAVHLFVQYFNFCEKHMENLTEKLLKLYMSNSSLAPNFINLINQTQILLEFHVWPVTLSKALQKEIVNLPTDKWTMKNLGWHLKILSRVAQENSISQSSTALFLRRVVFCSDLCSKGDWRTGNALLSVCKHVLQHQKLSAIFVHLADLLQYLMHRFEDIDVQDRARLYYVLLTNVSSDKLGKILTMSPARGQTKSRSLSSIMTENENFSTMLTIRNAEKTLLCLQPVLEGIKAFTCISDSPSLYCIVLQFENTDCRFESISDINVPCLFVDRKPPVVTINLVPKEPYPTIFSVSATYSTQDGITYQTKLDPLYITFREMFIPLPLPALWPLESRFDLFGKLWSAFKPDEQNQFEESIFCYEMSNNSLHDIVLDNFSKFAVSCNGGEYKIAVFLPPQFHILMHIKSQDDTACFSVRTDNWNLLPYLNSHLLDITLQ
The following text describes a protein:
Function:
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
Subcellular Localization:
Secreted.
Sequence:
MNKILAITVFVAFLALGAESFRVPRQAEDEKGTIAVVVDTLKSYYDQSVDTASGYVETIKGYKLEEKAKTIYSDTVRAVGTYAGIFQDQLYHILYSQDSH
The following text describes a protein:
Function:
Probably involved in copper export.
Subcellular Localization:
Cell membrane. Endomembrane system; Multi-pass membrane protein.
Sequence:
MKCSHCQLEFKESELFKEVINHKELHFCCTGCARVYALLLDLNLESFYDKLNDSTLAPVTPQDSMSALELEQALEENNKGDFILNLLLEKTHCNACLWLNQKVLERLSGVKKVSVNFTTHHLQIVFEKSLNPKEIIQKIESLGYGAKIYNAQNYTLKAQKEQRSYLLTLSVGFFATMNLMFIAIAKYASYGGASYGGANYGAGMDKLMQRNLDLVSLFLSLLVLVVVGRFFIKGAFYGLKNGVLGMDLSVSFGALSAFVYSVYAMLVSQETYFEASSTILTLVFGSKFLELKARLFANEKCLALESHEIHSVIVVENGKQTEKHPKDVAIGSVVWVPSGAKIALDGVLLNNASVDASLISGEFKPLELGVNDPILGGYVNVGVPFSYQVSANFQNSRLSGLLETLKKSFLEKPLIESSANQIADIFSKAVLFLAFVSFLLWQFGLGGNFEKALMVCISVLVISCPCAFALATPIALVIGVFKNPLIVFKEALFLETLAKVKKIFIDKTGTLTQKEVLLKEKIIYEEFDGRLLKSLLKVREHLAHSAILKSLDGDEVSLEKIEFFAHGLKASYQNETLLVGSLKFLGSMGVDIPMKESANIMVGFAKNETLCALFILEERLKANAKEVVQALQNKGLELEILSGDNESSVKECAKKLGISNYHAHLTPEDKAQTISSYKGVCAMVGDGNNDALALKQASVSLGFEKSALSKSACDILLLEEDLSLLKKAFDNAQKVYQVVLQNIVLSLIYNAILIPVAMLGYINPLIASLSMSASSLLVVLNSLRLKRS
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MEESHCSDLISKRQRLDSYIAGDITNPKGEGSSKLVQFADNVVYRLYFKGLVSDEVAAAESGERTVTAGFGVAICDVADNLLYEMKESLSGGGEVKRRGVEIRALIHGLSEAFNMGIRHVRIHSDDYPIFQFINGGDKPKQNDMRQLVNELAREAIVSQSSSLDLKAAQGTTCAICLEETDAGRMFSTEQCLHRHCFSCVKQYVEVKLLSGIVPTCLGEGCKLELTLESCSKILTPRVTEMWKRKMKEDSIPAAERIYCPYPNCAMLMSKSDLSSHADQSKVQECVKCRGHFCIDCKVPSHTDMSCDEYKKLHPDPLVDELKSLANDNKWRQCVKCRHMIELSHGCNHMTCRCGYEFCYKCGVEWKKNQNSCPSGCLLTGHGDYDDEDDDDGDSEHSCEEDMCECYYDDDGVRWRDWEDFVDHQPRVYDMSPLPPGAVHEYEAFDIEEGNDDEYDDYNNYGGLTESDHDGGFNEDVYREYYSL
The following text describes a protein:
Function:
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSEDNQKVLPFLEHLVELRKRLIIIIVAVVVGMGFAWNLSNGLLHFVTKPITGETYLTDIKKQVYQEVGKRFPAAYKQFELEKAMNAAPKERKLNYSAPLEPFFVQCKISVIAGFILALPVVFYQLWLFIAPGLTRKEKRMVLPFVTVSTVSFCVGALFFLVVIWPVIINFSLSYEAEGLNSLFNMSAYINFCLRLILMFGLIFELPILMLLLSRFGIVTYQFLARNRRYALLASSIVAAFHADLITMFVIMVPLYMMYEISVWLVLLFGKKKPVEAVAGEGPTGAAS
The following text describes a protein:
Function:
Component of the clr6 histone deacetylase complex I' responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Has a role in silencing of mating type genes.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MGTSGIEIFAALNDFTDAIVSVPESVCGKFTSLKEIDAQVRDIRQNVIQEIGVVLKNEKNDELSGEERCERLQKTLKEILPYSDSKICLATDAMNNIKSCIDRLDAGFEYVELEIPQQLRLGYPDDRALMNYHSTVTPQTSERRRETRRHQNNQHSQQYSSQERSSSYNNFEDASSPQSSYHTPTKRRKNAVPRKSSSPPLSSTKHAPQSTERRPVRRSESRLKQTNGEPLVKHDTLDSSDISREGEQLYCYCQQVSYGQMIGCDNENCKREWFHLPCVGLVEPPKGIWYCKECEELAKSSESRQ
The following text describes a protein:
Function:
Probable carboxypeptidase.
Subcellular Localization:
Secreted.
Sequence:
MANDYISSVLKWLLLILQLVFLIQHRAYSASIVKYLPGFDGPLPFELETGYIGIGEKDEVQLFYYFIKSEGNPEEDPLLLWLSGGPGCSAISGLLLENGPLAMKLDVYNGTVPPLVSTTYSWTKSSSILYLDQPVGTGFSYSRTHLVNKPSDLGEAKQIHEFLQKWLGKHPEFSSNSFYAGGDSYSGKIVPALVQEISKGNYQCCNPPINLQGYVLGNPVTDGKIDSNHRIPYAHGMAFISDELYESLKRNCKGEYTYVDPLNTKCLELIDEYHKYYRCLLVTYWANDKTVRKALQINEESIGEWVRCRYGIPYTYDIISSVPYHKNNSINGYPSLIFSGDHDMAVPYLGTQAWIRALNYSIIDDWRPWMINDQIAGYTRTYANKMTFATVKASGHTPEYKPDESSIMFQRWINGQPL
The following text describes a protein:
Function:
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Miscellaneous:
MISCELLANEOUS: Present with 1630 molecules/cell in log phase SD medium.
Subcellular Localization:
Endosome.
Sequence:
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC
The following text describes a protein:
Function:
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
Subcellular Localization:
Nucleus.
Sequence:
MAAMNDLVPLGRPKTKHNALGGFGAQRTGTVKPKEESKPPPQLPPLQQLGPACERCGVSKDLYGSQCGHLTLCQACGKALKLEGAPCKSCGEKLDKLVREYAISSIHHPRSHFIAKYPDGSTPPPLNNRKRWFMQRDAPDGRPTGPDAREKLKGLRWIMGDMTEKNIFKGSLEGGQQASYMALIMADNKLTTFPISSWYNFRHQISLKTRTLEEAEEHMKRREQSSTTYQQWMLRTANSGTGAFPVQNGGGAGRGTVPREEGGAVSDDDGQEDARRTRPARRDEDGDEEAGRGEDWEHDEAFSDDDEAPGTGEPEEREEQEQDKKAPPPKEMQEELEGQRSDSEGEGSGEGKQLQRLLKETGEGDDDEEEEEEEDEDEEENEDLLEKIGALGAGAESRPAPKAREASVEPGAGAGPSGRPGTAGGKRKDMAGPPQAAQKKQKVETAPKPPVAAPAGPSKPPAAAPKAAEKPANPRMLTVEFLKETLRETGPMTLKDLLALLKKRNCNPQTKEEKDNLQAVIKKAVSVEKINGVSMLRAKN
The following text describes a protein:
Function:
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Subcellular Localization:
Nucleus.
Sequence:
MMEGSNSLDDSPSRQAQAQTRTHSGGGGGGDAPSNPSQPQPQLQSQSQREGEEVDETKKEEEELIEKAQKRIDKITSSPDNPNPTLLHALSSLLETQESLARQLPEATLENNIRAADERSLADLDESSLESVGEDNDDIDIDGGERRHGRDLRDVKIKFAELDESGRDDLLRHRPSRGWTRHRGRGRVNETALKNEQVSTSPDSGSRSGSGPGRSARDRNSKNLLDVKKGPDTRKFQGNILSDGLNVERDDNDDCFQGCRIGTKDISDLVKKAVQAAELEAIGANTPAGAIKAAGDAAAEYGSRLLIAPAPSPTAGDTAAGINGCLLLLRHPKSGNATNYLLSHDNEGAVLQELHWFKQSYTSWFLGDYVSQDGSLYTATPVDPVFILLPIFEEARMKKRDDLGKFRQLDEIIFINDYPGYHHLMSIAENCMGVVCEIKEIGSSKFFRLDDSKVLAWLYCKVFQLKKALCSLDKNYAAQDEKYTLAGAVSILGEYVKDEPWLMLLLDHLKLNLLEVTSKVPEAENFPTNAEHNPVSSSLLQEKDRSEDKTKRSGKQAKKAKVETESRNIREMFRRACRKS
The following text describes a protein:
Function:
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
Sequence:
MKQNFFAVDLGATSGRTILGSFIEGGLNLEEINRFPNHLIEVGGHFYWDIYALYRHIIDGLKLVAHRGESIASIGIDTWGVDFVLLGKDGNLLRQPYAYRDPHTVGAPEAFFSRISRSEVYGKTGIQVMNFNSLFQLDTLRRNHDSALEAADKVLFMPDALSYMLTGKMVTEYTIASTAQLVNAHTQRLEPELLKAVGLQEENFGRFVFPGEKIGTLTEEVQKITGLGAIPVIAVAGHDTGSAVAAVPALDRNFAYLSSGTWSLMGVETDAPVITAETEALNFTNEGGVEGTIRLLKNICGMWLLERCRLNWGDTSYPELITEADSCEPFRSLINPDDDCFANPADMEQAIREYCRTTGQPVPEQRGQIVRCIFESLALRYRQVLENLRALSPRPIETLHVIGGGSRNDLLNQFTANAIGIPVVAGPSEATAIGNVMIQAMTVGEATDVAGMRQLISRSIPLKTYHPQDMAAWDAAYIHFKNCVR
The following text describes a protein:
Function:
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
METPPAAAPAPLPPPARPSTPSYTVECIFRDFTCRRAALIRALTTDEKAFSRKYNAGTESLYLYGNSDGNWELRPPKLLMPPGQPDPRMFGIKLVRGNMKHPKWLAYIATHCDAWLIRISFFLGANLGTQARQHLSALINSLQTVHEAFVASDTYHRICHLEKMNVEIEDEDEGCGTEPTVCASCGNHYRRNGFWICCDECDRWFHGKCVKVTAAQAEHIGHYECPECCSDKKGHDYNVDPLLSVLYKRY
The following text describes a protein:
Function:
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.
Sequence:
MEHLQEELYKQIKEEKGTVTIFLKSGVRIIGEVVGVDKFTLLILVDGKQQLIYKQAISTIMK