lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
Sequence:
MLGKGVVDYTREGSILSAEQRRFYEKNGYLLIRNCVPQYELNRFRQRFQDICEKKVKAPENMTVMKDISIAKSEFKDGEKAITKIQDFADDPVLFEYCKYPGVVDVVKDLIGNPKSNLMAMHTMLINKPPDNGKLTSRHPMHQDLQYFPFRPADFICCAWTAMEKITRANGCLVVVPGTHKGVLLPHEYPKWEGGVNKAYHGIQDYDTSTPRIHVEMEPGDTVFFHPILIHGSGANRTEGFRKAISCHYANDDLCRYVNVEGTTQETLAEEIIEIAKKRLTRYGLDPNTVTLDFADIWRVRAREVNGRRSNL
The following text describes a protein:
Function:
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. Subunit 1 binds to the primer-template junction (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MAKKANKEQSPKKTSPTSSQGSTATKKKTKTSEPAGTDIRNFFAVIKPSTSGENVKNDLFSKAKEDSNKEFSLSDKENDDVKIISNKKDTTNNDKKKPSENKSPKKKEPSKSIDLTSDEDKSSSEEDKKKPSSSSSKKKPSSSSSSLPNKKKSTLKRLKKKRDDSSSSSSSSESDFDSGSDLDIESIDQKPKTITKKKNLKRKSKPDSSSSSEDETKHQKDKKIKLKTPEKKIEEPEKKVEIPSSTSSISSSQKKIVYSFEDSEDSDADKPIPPSKKPSAVVVNAPSTKTFEKKKENTDIPPSPSKTKETTSTTTDTKPIKSPSKSNKSTTPTTTTPITTEKKKIAQLEFESPIVSITAIDTEKKKDGNKDNKNKEKDKDSSPFDEMEIEESKSKTIMPNNNNNNKSKESSSSTTNSKNNTSMNDDLIFDDFAFSPIKSGSNKTTPSKSTSSPSKETTPIKTRSKTVESKFDDDSIFDSPDKKTTTTTASNTKTKTPPSKKDKFNHDIIFEESDTPLNRAIEDSIVKRSLSGLNNIDKDSKTTTTTTTEKKQKLKSDPFDTETEEETEDEGDEPLYKQQSSSFGSGSINPTATPTTPTKKPAATSTNATPTKKPNPFMYMNGRPTPPNKGSKPRPQGKENCLRGKVFLVSGVMDCFERDEMHDIIKRWGGKVAKSAVKLLNYLVSGKDVGEKKLEGAKKVGAKIITEDEFLEMINKTLPKPVSTTETTHISLPTPTPTPTPTPASSSSSSTTTTTTTTTTTTNSTGIKGPSLPVRSGSGGSSTGIKGPSLPVRSGSGGTTSSSPPLTFTSSPPTSTTTATTTTTSSPPISMASVIVPKSISTIPKGHDILWVEKYRPKVIEDIVGNPGIFQEFGKWLDQWNSTAPRDASKKNAVLLSGPPGIGKTSAALLICKQKGFEAIELNASDARSKSEIKRLLSGVSDNQNITKFFGTTNQDTGKDVQANKKIKTAIILDEIDGSSGNSDRGGIAEIIGLIKKSKMPFICLCNDYYSSKVTSLRNHCMDLKLRKPTLNQVSSRLLAIAKHEGMKVSSYMIEKVYTSSHSDIRQSINTLQMMSRSKRDYNNDNVTQSLQEKDFDISPFTAAELILREDNSNINKKLDYFFSDFSLVPLIIQENYLKTRPYGGGSQSKYNDCELISMAADALSDSDQFGRAIGKEMAWNLLPTYGVTSCIIPSGYIRGSPPMPLSFPSYLGKYSNASKQQRFVRELQLHMRSTSNTFVNRDETRLYYVPMLKHHLIQPLVQDDNDGIENVINVMDEYGLTEDDRNNIIELSTWGKEDPLKDVKTQVKSAFTRKFRSTSHAIYDVSLLSSKGSGGGGTNIAEGYEEVEGESQNQIEEEDEETEEKDSLPNLVKKSSVKSKSDTKPKSTKSKSTTTKSKKK
The following text describes a protein:
Function:
Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.
Sequence:
MLNQKVSSQPIETPIGPDEVPEASKEEKDVWKSSRASASEDHVPAAEQLEEDDTENDTILRHYEMGDKLGKGGFGSVYKATRRRDGLEVAVKCTVKSPKMKEMTVPGYDKPLPTEIALTIMANNGPYVPEIIQLLDWEDNDGHYIIIMERPIPCMDLLGFLRHKDGPLDEKTGRHIMRQAIYAVSVCFDRGVFHRDIKLENLLVNPDTLEVKLIDFGCGAIVKKSGYKVFCGTRTYFPPEYELHGRYHAQPATVWSLGIVLFAMMCGALPTVSDHSLIRDYLWSSPGLSIECCQMICGCLQPNPDERLALQEMHLHNWFKV
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MLKEEATGTVVSASEGTPKRKKRKRKKKMQEQPESKQASPGVVRVNKIVSNKSENGCADGIEASGHADVNMDPINANVADVLIENCSENSSLLQESSAGRKRRKRKRKRGSSIRGPGFHDLSCICASCLVEAHKEKIKSIYSPRGSLVRFQRKKLLILDLNGLLADINQDTHNAHKAHAKVRGKLVFRRPYCDDFLRFCFENFELGIWSSRKRENVDSVVDILMRNLKPYLLFCWDMSHCTVTGCNTIDNKHKPLVLKELKKLWNKEEPTLPWEQGEFSPSNTLLVDDSPYKALRNPPNTAIFPQPYSYRNERDDYSLGPDGDLRIYLERIASADNVQNFVRDNPFGQNSITESDPNWNFYVQIVNKVEKQVVDKVEKQILDKVENQIADKVDSQIADKVGIKVQSA
The following text describes a protein:
Function:
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Sequence:
MSTNISCLNFYKGKSLLISGCTGFVAKVILEKILRVLEVKRVYVLVRAKKGQSVTERFNKEIINSQCFDRIRKQKGADFQKFIEDVVKPVDGDLIKPHLGLDKEVRQELIENVNIIINSAASVDFNSPIKVALEINYYGVQKVLELAKQCKNLENFIHVSTAYVNSDKFGFIEEKIYHPQKDVESFVSVLYRSSQNFDEKQQKLALDKFPNTYTFTKNLAEQMLAQLRPPNMQITIVRPTIVGCSFRDPIPGWIDNLVGGAAVIFFGGIGLVKIYKGKENLITDQVPVDFVSDMILVAGAYEANKNTFQIYHCGTSARNPAPWKLTKDTCVEYWNANPPSVKVSPCTIEINNNLCYYRYMNFKRKMGALALKTFADTFGNSSQKKNASRYLKVIDKADTINKTFKHFNRNEWVFSQENVLQLMNCLSRDEQGIFLLDVTEMEWRSYMMTFHYGLQKFILKENVQPPVDEEPTDLLRSWKSGNFTDLKWIVEKQKLPVENKNYTMNGLFNRQRAKL
The following text describes a protein:
Function:
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MAEPHKQDIASIFRRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNSNATIFFRQHGCSTNDTNAKYNSRASQLYREKIKSLATQATRKHGTELWIDVYGAPPLSPQQQEEEDFFASHSEQVNNTAQGAAPQVEETPLTISNKEAGEPDVGPSVDYLSMSPKASLESVSVLKKKSTAAKKGLGAKKGGLGAQKVSSKSFSEMEKHAQAVDKQNEQEAVTTTKKEEEPVVTSLRLAYKQLEIQKQKDDEKLKNLPPKKAAEAERLGMGFGTRSGISHSVLSEMKTIEQEAPKNVKAKKLYQQEEPEDLYFSAPRSRYREDPPEPLISSFLNWEEQSDDYWKNDKTSADPDVSLTSKTTSYNDRPATRRKHDVEPVPTTDDAQKKFGNAKAISSDMFFGKQDNADYETRSRLERLSGNSSISSADLFDEHKKDPAGNYNLTRVLPSAPDMGNFKQGVKSVAGRLSVLANGVMTTIQDRYGS
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MGRNDGETRDYGGADVPLIASAGGFFELRNRPRRDVSWLLAYLLFLGVSIGGGIFAFYHRNTRYGEFVSPDVWTDPKLCPVGSNHATRRLLQSPDDPDAPPSFDLGLFVKTAGAWIGASVGGAVLVGLLFVWLVRVSPAGLVGAPRPSARTHAHTHAHTHAHARAHTRTHARAQTHTHTHVAVPAAMGAVSLAQGATVPGIILLAFAGLTIILFLLWRPQVELVTRLLGLAGRGLSANPGLVPLALGLQVFLLGLLELPLLLACAAAYMNGSVAYNTQRADGGAATSADQCVDADGNQVLCCTWQVEPWVPGYLGLVGVAMTWSMFLAFQVKLFTVAGATAMWYFEPRQQQEARAAGSRTLKCLGFAAGSSLGSLCCGSAVLTLVSMIRQAMQKARQERDRNLLVACAAACLSLLLSLLEYVTRFATVRAAITGEAFFAAGRNVVALLSRNAMDAFGVWWLPPMILQSCSFILSFCWAVAVAFISYATTWRHQHPEPGTPAAAAGNQAATSAVLTAVVAFFASWAVLGFLASLLLNVIDALFVCFAMDRDAGQVSSVEVHAVLTKLPTVGAVVQQPDGGIAYGATAPPQEQHYPPRGYDTRV
The following text describes a protein:
Function:
Involved in transcription. Probably functions as a transcriptional activator.
Miscellaneous:
MISCELLANEOUS: Deletion causes a slow growth phenotype on synthetic medium at 37 degrees Celsius and leads to decreased transcription. Deletion has no effect on ribosome biogenesis or frequency of recombination. Deletion is synthetically lethal with a deletion of each of the THO complex subunits HPR1, MFT1, THO2, and THP2.
Subcellular Localization:
Nucleus. Note=Mainly nuclear, but might shuttle between the nucleus and the cytoplasm.
Sequence:
MTDEKRAFPKGNNHIRSETFNGSVSHKISESIKDIASLRPHGKYTVQDIDNIIASTSSHENRGQSGDSNGCINHDEEGDIPMCDLNDESDVEMISEYLSSQREMEAQSVANYMPKINDDLPLLNPPTLKTAFVVDTNFIISHLNTLEKLRSLSSTYHHLIIVPTTVIQELDGLKKSPDIARDNDDTTNQEHDRTIGTLARWGNDWIYKNLANLDSGLIGQKLKQSLNPGSLKDDSILDCCLYFKEILNCFVILLSNDKNLCTKALTEDILTVSFRKNMDAKIIAMRAYEENQLRFANLRDSTVNNFDQNVTSYAHIPGIETPPLQFDKVSQNVFEQVKETIFFAIDHTLRKEYGEDIGFIDYNPDKLTTIENASNYIYLFWVSVFSELFTCSKIKKNEWKSLPTVLKSKPTNLNDLRTFEQFWETVLHFLFSKFTNEEKQSLEKQIHEWKTSINAIST
The following text describes a protein:
Function:
Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors (By similarity). Involved in steering cell migration by controlling its directional persistence.
Subcellular Localization:
Cell projection, lamellipodium.
Domain:
The acidic C-terminus is necessary and sufficient to inhibit ARP2/3 complex activity.
Sequence:
MSRIYDNTALLNKPVHNEKLSFTWDPIVHQSGHGVILEGTVVDFSRHAITDVKNRKERYNVLYIKPSRVHRRKYDSKGNEIEPNFSDTKKVNTGFLMSSYKVEAKGETDCLDERQLREIVNKEQLVKVTIKHCPREAFAFWISEAEMDKTELEPGQEVRLKTKGDGPFIFSFAKLDSGTVTKCNFAGDENAGASWTEKIMANKSNQENTGKSAAQGEGADDDEWDD
The following text describes a protein:
Function:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MLLTAPLLVLCLLAALAIFARRGLSLYPRNAVGFLHPSAAAGGGGERVLWVAIDSIQKDDIKNGIDRLYVLYCTQTSGKSDDGRCEPPQEYLARVVQKQFHITLPRPIKVVHLRSSMTKWLDGGRYPFLTLLLQVVCGSILLFYESCVVNTMTPTVIESVGIPGVYPLLSIFAGSRIVAYTHYPIITPVMTQRVENGEMRYNNKGAVARHGVLRKAKVLYYKLFAHIYRWMGKFPDLVMTNSTWTKGHIQQLWGHDVPVLVYPPCAVSHFMPLRKLPHQRINTVVSVGQFRPEKNHMLQLQSFALALPRLPTDAKLIMIGGARNEEDKQRAEAVKVEAQRLGIADRVDVRVGAPFSEVSESLAQCCIGLHTMEDEHFGIVLVEYIACGCIPLGHRSGGVCLDIITSPNVGFLAATAEEYADCMAEIFRIKNDEPETYRKFQECGMATIARFSDESFGEKLTASLRRHLPS
The following text describes a protein:
Function:
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MDSLICGACSAIPPSCVCVVLEVFRRNRDHRLGVRMITAAAAAEDRGGAPQLVQFMTSCTGCQRGENPTWGLTNQEKTSTRVSSLVEWCVGGQSLSFRGRVALIEDVELSLACSCFCMYWFSRHTSFGVGGSFKVVVLYMNANFSGFRVGIFMECALHLVLSGYDRACPKSLILSASRTWLIAVHKLEQELLSQRDLRFCQCPDNLICDHRGFKTLASMAVDNLTPTNAPPPQAQEPGKSLPIKAWYYNPSDAHPSHPHQYSPNREVSTDHLHKLGVLTWTQIETDQFENNKFLNKIKTVRGYNYEEVLTVAPENLQNFEENTRRFFMEHLHDHEEIRFILDGVGYEDVRDFDGKWIRIEIKKGDLIVLPPGMYHRFSLDSNQFLKALLLYQGNPTRIQFERNPETDLMEVRLDYVQSVLEAQMLHAATEVEEKVLVEATEALGAIAV
The following text describes a protein:
Function:
Functions as an E3 ubiquitin ligase.
Sequence:
MTVKIVKCEREMSEHFAANLADHSMIESLIHKLNSIGPYDQWIATGEISRLTKRSPENRVAFAQAGAIPLLIDFLTSTDLQTQENAMTALLNLSIYEYNKGIIVSSGAIPRIVHVLSKGSMVARENSAATLFSLSVIDRKELMISSAKAISPLVFLLSEGTERAKRMATNALFNLCIYESNKKRAVRAGLVPMLMELLEESHGLLKDKAIAILAILSMHLKGRLAIGKVEAVPILIEILRSGSPMNKENAVIVLVELCLEDQKYLVEVQEFGAMDKIIHLLEHGTYRGKEKATKLLEKIKESE
The following text describes a protein:
Function:
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
Subcellular Localization:
Mitochondrion.
Sequence:
MLLRFITTTHQLNWASLYYFTKHTRPKAQPHREKTRAKAISDDKSGKIAKSDQEQEQKQQQENLKKKIELEKLRALQPKMHTWSSFYETHIPQTNKIPKTIYLSLDQQPEGRRKHYKKFVQPPVDITEENNQNFQIKQHTYEDPFAQPKRAGLIAVKVGMTAQWDKWGYRHALTVLQLDNNQVVQVVKNDTYTGLQVGAGAVNIKTLKKPQIGHFLKANIPPKKYIKEFPITPENVLPVGFMLTARHFTPGQYIDIQGISTGKGFGGTVKRHNFKTQPATHGNSLCHRQLGSTGQRQDPGRVFKGKKMPGHLGNDKVTCEAIQIYRIDAVRQLIYIKGSVPGKPGSIVYLRDSWKAQKKNKELLNFPTLAVENGKEYAKEIVMEAPLEDPEMEETHENDFPKAGEDAED
The following text describes a protein:
Function:
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.
Sequence:
MSSVIQLNSISIKNETNCGYCNGGKSNKLWVTSGFYCYKMKVDEYQQLMDRGWRRCGVYYYRPALAQSCCQAYALRVVASKFQMRVTHEKVLKRIKRIKPVLLDNSNVPLQQQQKDQIENDTFIDLIKQQLQTDLDLSDLIILEKVGQHYTFKSIQYKEEDHIKYFKSIIITSLQKITKQQLNETFAIEKEELSNLLYQNFINSISELQIYEILLIKGYLNKVESDWAFGCNLIPYLYSKITAFLKNYNLPVLKLEENLKYMELIQKYLQNLGFEFKISELDHQLLIKTPQTLKEKILKSNILYYLQKFDLQSNQPQEITKKNRHQIQIKWVKAQFQDDSFEVYKKYQRAVHDKERVSKMSYCNFVCVDALDSQELGCWHMKYYLENQLIAVGVVDLLPECVSSVYFFYDPDYKKYSLGVYGVLSEIEYIQKKQITNPQLQYYYMGFYIMDSKKMAYKAEYTPCELLCPRTYRWISLTKKIKEKIEKITIYVQDVGLVDERDQEHGYSINLDGRTIDDMNFLDVDIENFIQQNVKISQTGKQFTISQLKKNYQQYFMNLFKDFLKKIGKELMKEFLFAVN
The following text describes a protein:
Function:
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
Miscellaneous:
MISCELLANEOUS: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.
Sequence:
MSGFGGRGVDEKGFLRWLLGELGVEEDDVAYVDGLVVKVDGAAASTSRLPFQTWADFGWRNVAAAYSDVRVKFAEARLLLASVTAPDLGTAAEVVQGVREASQFFSLAYVGGDLNEGRDVVVDVVLVGWARARVGRAPRPGDVLVTIPQFGYTSLAYRFWQMGGAVVERGVEALKRPKPLWPLPPAECVTAAMDSSDGLGDVLWSMARGVDIVVKELPAPREVLEFAAERGLDVGEIVFNGGEEFLPVFAVRRDCPVESPYVSFAEVVPGEGRVWWRGEELKWRGWAYFRGWG
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MGTHMSRAVRAHDSSQSLRSLNFNKQEDSSVKNKSNTMKHHSSSEELDSMPDENEHSHHSTHSNQSHRSTPSSRDTPQKPMHRNHSFGDIHLMRNAAKHNNMPRNSSYGDVRKHRHHHDLHSVSKRFQQVLGRSESFRESREIQAITFKKDFQTHYSCDLRSPLSHGRYATVTAALSYLTAENVAVKIISKDRLRSKGVPAPRANAHERTMRTAILNGIKSCSWLYDKKSGRRCAGENVRVEVLALRNLANQPNVVKFVDVFEDEAFFYLVMELCKGGNLLERINKVKNMKEAQAGPLLKQMLAVTNVCHAQGIAHRDLKLENFVFHSETEDYPLKLVDFGSAAFFRHGQNRPFKGAAGTFNYMAPEVFESNYGPIADVWSLGVVGYSMLCGTLPFSGTTCEVLKEKILHDEVEFSHPAWGDVSECAKDLLKKMLEKNPDFRITVDEALSHAWFRQGGGGEGSNRCGGTESE
The following text describes a protein:
Function:
Transcription factor that regulates pH-induced filamentation with RIM101. Required for yeast cell adherence to silicone substrate and biofilm formation.
Subcellular Localization:
Nucleus.
Sequence:
MLSTMSNLPIVAGISTTATTGTTSTATASTSTSGSVNTTATNNNNNTSASNSTSASSATANGGIGTNSGNSLQYYYTGNNTSNSVDGNKYSLPSIYFTPQDSINNTSHTYNPYTTVSGAVTPQNYQLDYSQSSTVNNNYQFTLPNQQLSSPQQQQYNRSYSNSLMPNYHYNNTTTNINTNVGSNTSPQLSNSNTPNPISPVLIPDKDNTYNNTNNVLVSSYPSMTMNQIQQQQQQYLQPSQQYQYSYNQYYMQPYYHNPQQSAPQQVQKPAQTEKLPHLSVTNIDYSSLVSYTVSPSLKRKRRTAKKSLSPSSTSSLSMMINHDSTNNGTTSTATTTRSSSTSSATSSSIGVAAADSFPCPQCNKVFQKPYNLKSHMKTHSNEKPYHCNICFKRFARSHDKKRHELLHQGVKNFKCQGYLNDGVTSWGCGKTFARSDALSRHFRTETGWLCIRPLMEEAKRLEEEEQQRQQQAQQQQQVPQQSQVSEQIGVNVGEIKFNDEYYDNSNFIKKLLQSNK
The following text describes a protein:
Function:
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.
Sequence:
MTESVPGPFFTTATPTDHIQDEQSPYTGYFESLSENDIHLFFEIEATSEWIRNSNHQRIALQFPDSLLPYSKRVTKLIESKIGDDENPEIVKKTFVLADTTYRSCCVDEVAAAHANCTALVHFGEACHSAPTDKIDVKFVLGNLPTFIDEFRVKLKEIVNELSTDHIVLLMDSCFAHEQEKVVAVIEEIVPPTKKVSCASLPSEENLKEHRKNVYLGREISAALRDNLPADLIFCGFPNSPLLPIWLLSYPSCMTVTHYNPMDKSIQHENTRSSRLLRKRLFLVEKLKDADTVGLVVGSVGVDKHREAVKRMRELCKAAGKKIYVISVGKINVPKLSNFSTDIDVFVLLSCPFGVVLDSSDYFRPVVSFFEAEIALNPSKTWAADFGWSAEFAAFLEDKIETEVPEVDVGDFSLISGKVRVVTKEDEKEGDGPRSIAIYNPGYCNDRTWKGLDDGITASEDSTTVTEGRSGIAQGYSGK
The following text describes a protein:
Function:
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
Subcellular Localization:
Nucleus.
Sequence:
MLQACSPSHDWFCDSEPLLFDDEFSMSLMKDLQCIPTPPQSPPMKPGLAKNMSTVDQLELVSELLMEDTDFLQLDWNFTGPASSADDPLSEDCLWRPDGDKQTEDKLSAVLSTSPLLSDIDTQIFAEIAGSTLDCHTAALACQALESEDSPLDSQEQIESTSDYGSLSTGGESSTSDSEEEIDVVTVRRSSTLTRSQHQQQLEDSRREQQRALKRYHFEIQQQHNYAAPRPASPPPPPSPPLKRTRGSGDSQRGLQIPGRSRSLVVRQPVDTEDEEERRRTHNVMERQRRNELKNCFLRLRDNVPELSNNDKASKVVILKRAKESIRNLESENQRLTSKRDKLRERQEQLKARLEQLKRH
The following text describes a protein:
Function:
Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MELLYSLPFYVLEVPNLKLKKPQWLHQPSAMVVYSLVLLSYFLVCGGIIYDVIVEPPSIGSTVDEHGHSKPVRLSNSCGFLWRGATCSAELIFIQSKCPWTALHAKWRGVFFLWDPSTNVVNESLSLLRATKTKIKKSAHAPSVTNENAQLYKFTTGKSIPTLCIDDILPKLKTIPFPPSRA
The following text describes a protein:
Function:
May be involved in 20S pre-rRNA processing.
Sequence:
MASTAQSPSLFYQSIQAILKSWTGLQLAVAHGFGGLHSSEKAQWLVGVIETFFKENDDIEAYELEDFIDEIMATEFNTLSEDDGTKVISQEICNQFQYWKEGRYKEMKERLQKLECVNLAECMNGNMETSEQIPDEEANKILEGMTICGPDAISGDTSVKDTEKTFNETPGASDLIADDEWTTVTTRARRKRNK
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Sequence:
MTTPAEPLRYAILGSGAVGGLYGAMLARSGCDVHFLLHSDFEHVRENGLRIDSVLGDFVLESPQVYDSVESMPKCDVVIIALKSTRNALLDEWLPRVVADDGVVLTLQNGLDVEADVRRTIPAGRVLGGCCFLCSNKVGPGHIHHLDYGRIAFGAYQEAGVDPLRANEVGRRIEADMQSAGIDANWSDDLAKTRWRKLMWNIPFNGLSVVLDASTDRIIGSQPGRDLANQLIAEVHAGAAACGVEIDEKAIRATMEHTETMVPYDSSMRLDFLAKRPMEVEAIFGNPLRAIGDRASEIAPSISMLYQQLAFFNEAICQDA
The following text describes a protein:
Function:
DNA-binding protein that acts probably as a transcription factor.
Miscellaneous:
MISCELLANEOUS: Present with 672 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSSEEFKGLPIKRDISSTIYADRPPALSAPPCVGATGNDKIQVLPIPKKSRTIKTDKPRPFLCHICTRGFVRQEHLKRHQRAHTNEKPFLCVFCGRCFARRDLVLRHQHKLHSALVSKESINSKDKTEIDAINDKNIIQIQGNKQTILPTPSNPLAKTAVQLKKAAKEKKNGKQGKLDLSPSYGANNHSTDVSPSVGNSSTPAVIEETDSSSHFPLPDTNIPTKSKRHASFSASSAFTYSSDNFQKLHQQAKSDFDELQESIPHQVGFSTPQLTAQQLIENAIESGVVDLETLDLPPFLSLDGLPPASSSAAVAASEQIDICPSSATDTISGANSTPNQAATAPPFQLPIARESSSLFLANTPYLSDFLTMGSSYGGSGGFAKSITADPSLDYFNYKNHSHPDSRHNNSSSGINYSNNKNNNESIEKSQNNSNVINETIDHTDIHAHHADAHDDSFIESEEWLSKFIMDSQIDNDLKLNINHFNDIGFNNLHPQNPTTHSEPRNMHNENRDMHRSASKFQSVSENISPREQMSLFKTKQNKAISKFLSDEKIPSTASPSSSASPVQFDKKNVDINEFLLDESVSNLFTTRQIDLFKKNVNLYSPLFQNQKDAVSSTSLTPSLTTQTATTQSGPGWTDSSQKLTFFTEQLRNLIIKENNLKSNLFPTVDELNHYVDLYQVEFHKYFPFIHLYSIIPSSENYPLVISISMIGALYGFHSTHALLLSKIARTRVRMFLENTRSNHDKTPIWLMQSLVLLTFTSIFSNDMNAFRTVNTQIMILVQLIKISKLNYPLENFIKPPIESDHVLEYQDNPAVLNQFKAQYNTREQINRNFKYFILAQSRIRICHIVLLISNLFKSLVDFDCCFHSIDLKCGVPCYNEVLFFCENSRTWNENLTRFNIVLDSKFSLIEVSNGESNYEKCLMYLSNGNPYLYKNAKISFKTLLSLLISIHEKINIERDALKDSYESDFHAKNVQWRMHSRPLVATMLKHWELLYIKNGGILALSDENLPIINTNPSFRLIIPLYFFAKLRKCLDIAPTLRCIWNQDWNSMNSSLEKVCYERESLREATEYAVSVITFWIDTVSVMKGKSTQTPIFTITCIFVSILVIAGYMRRLEDFAQNKNSDCMIGSLKSTDRILWLKAFKTLKRIESHLSEREYKLQTFAEFLRVPDNGSLDIESLDSSLIENTLNSHDVTNQALDIITRTRLSSRTLYCGARILGDTPVWPVSLLFAHALQSRAIYNINHRKSVNSV
The following text describes a protein:
Function:
Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
Sequence:
MSPFPAKSLLIALVLSWPASFDAALAAPVPASTYKTSGIPAPEAIGNDASRYKVTIYPTVPGIGTRDVAPDPDGSVWFNGQWSGVIGHLNPKTGEVKLYPLGTGSHPHGVVMGPDGGLWICDESNAIRRFDRKTHEVKTFQLPPFSGSMGYGNLNTPVFDGEGILWFTAQNGYYGRLDPSTGDMKIFPAPQGFGPYGMTATPKGEVWYTSLAGNYIARIDTKTYLPEVFPIPDDKANGSRRIWSDSQGHIWITTWGNGALMRFNPQNKSWDSYKLPGLGPRGYSTYVDNQDRVWSSDFGTNSIHQFNPETMSFTVFPGNKQNVQTLQMNGVGDKIWAGQQGVDQIVLFERIP
The following text describes a protein:
Function:
May play a role in the respiratory chain.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLQVVQSPHNLVFMGSIRSVVACLSLAAVARKMTAATGQSVSGTSAAAAGLLRLTSVPGYDHNRVNDVLLLRPAAETQRRCDNETQNLQDGNDHVVFFPGDIQNFQQEMALQPDAAPWQCWSLERVGLTLAHRFPGCHIWVIRASQMYLHKFSCYQNFVESNLFGAPEHSADYGAIRHLRALLGHSMQQAGLPNPLPPLSGTSTPGPLPAGFSLTIVGFSKGCVVLNQIVYELAGARADPELQLFLDRVSALYWLDGGHPGGSETWVTDKCALGELASSGVAVHAHVTPYEVRDPMRAWVGREHRHFIKTLEDLGARVSHKLHFEDEPASIDNHFRVIQEF
The following text describes a protein:
Function:
Intercellular communication via tagB may mediate integration of cellular differentiation with morphogenesis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKFQFSSPSKIFLFSSVILILIFIGIKFELLEDTNSNRNDKFNNIINRFINYNIDDSIYKNKQQQQQFSNKIYSNEKKILLKNKIIDTTIKPSININNNNNNNNKLNNNNNNNNNNNNNNNNNNNNNNNNNNNNYYNSIEYYSSFVSRLLKSNDDDGIYYDDYQSKYKKNHYIVQFKDRINDETREQLKEFLIGTDITILKEQPFKSHIVHYIPHDSFLVFMTKEQSVLLSSKEWISWIGEHEPSNKIHLNYHEKSIGYPVYIILSGSTNSLIQRWENTLNSILTSYNSKVKLTLINQKKLKSIVYCNDESPSSSSSSSCSLIGSEKIVYKWISEQSESNYIERSEKLQTANRLSPTVIFGTKDKLVNNDRIDIPLRGKGQILSIADTGLDGSHCFFSDSKYPIPFNQVNENHRKVVTYITYHDNEDYVNGHGTHVCGSAAGTPEDSSWAISSFSGLATDAKIAFYDLSSGSSEPTPPEDYSQMYKPLYDAGARVHGDSWGSVSLQGYYGGYSDDAGGIDAFLYEYPEFSILRAAGNNELFASLLAQATAKNAITVGAEQTAHVNYVSDALEYYDFSDNANFQRPCLFDKKYCNYTTAKCCSEVSNVKGLQLCCPASIKQNASDSFTTQPQFYNENNMGSFSSKGPTHDGRLKPDIVAPGEYITSARSNGENSTDQCGDGSLPNANGLMSISGTSMATPLATAATTILRQYLVDGYFPTGESVEENKLLPTGSLLKALMINNAQLLNGTYFWSASSTNPSNAIFEQINGANLIQGWGALRMNNWLYVKSSNPTPPSRWIGIGGLGKNQKATEWKEDSLSSGLNKSYCFTYKPSSSSSGSGGGGGTPRIVATLVWTDPPSYSGAKFNLVNNLDLLLLNSDDDSIITIGNSGGSLQPAGKVAQPDTLNNVEGIIINPTKAMNYKFTIAGTNVPIGPQKFSFVFHGENGQFDWADSCPQCVDGVQFPCLITNGIGIQSCGSDLLWTKCIVQSCNEGYNYNSLKNTCDKFLSYNYIIIIVAGGTMVLIILLLMWIKYQEYKESKRDSFRRFDDGTGIFVRPKDKDAKVTPPDLYNLVSPFIIELTIATACSLVATAASILQPFYIGNIVNNIPTTKSIGEFKSDFIIIFILAFIEFLFTNVGSWISGIVNEKMVMRLQNKVFRALIAQDMGFFQRNNSALLMNVLIVDTPMLRSALTGILLSIATGVCKLVGSLVFIFTISWKLSLAFFAAVPILGLVTQIQSQFTKRLTRQLLFHNSKASQHGTESLTNMHVVTNYCKQEKEMVKYSDQLMNVFITARKLIITNTFAGTGKWLLIESLTFVILYFSAYLVIQKQFTVGLMISFSLYIGYVVDASSSLFGVYVSYIQCLASATRVFMILRSAPRKRTTLEEEEADRLAGLSGGGGGGGDNGDDKKDKQNIENGKDVLPSNIITPIDNVENSNGKQDDPNNNNNNIGNLDYSEQLDGVSTVADSTVGLTKRELKKQKEKEQKEYFKQTGISVAETPTFLPSSYTELTECRGEIEFKNVSFRYPTRPDVQVLHNINMKFEAGKCYGLVGPSGSGKSTTLELISKFYPLHGETGGKIYMDGIDIAKIRPNNLRSFVTNVHQHPFLFDATIGENIGYAIDNPTQEDIIEAAKLAYAHEFINDLPKKYDTQIGEAGNLSGGQKKRIAVARAICAKRKIMLLDEITAELDPESEEAITQSIKVLTQGHTVVMVAHKVAAVRDCDKIFVLEKGYLVEEGTHDELMANKGKYYRMFSEDKDDTPLQNNNNNKNNNNNNNNNEPSSSSTPPNDQPTPPPQEQQEQKNDQPPPPPPQEQQEQQEQQQQQQQEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQNDQPPNDYDQVPPPPPLPSESPSPPTGNNDGQPLVQMDEENDEER
The following text describes a protein:
Function:
O-methyltransferase involved in the benzoxazinoid glucoside biosynthesis. Can use 2,4,7-trihydroxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside (TRIBOA-glucoside) as substrate, but not aglucone TRIBOA, caffeic acid, ferulic acid, apigenin or quercetin.
Sequence:
MGHQAQHGTDDTEELLAAHRQLWCHALGYVKSMALKCALDLRIPDTIDRCGGSATLGELLAASEISASNHDYLRRVMRTLTAMRIFAASHDPAKADDAAAISYQLTPASRLLVSSSSSVDDAAGASKENTTTPSILPNIAHLVRPNTISLLFSMGEWMKDESAASVSLYETVHRQGMWACVEDDAANRASFYESMDADTRLVMQAVVRRCPHVFDGIKSLVDVGGGRGTAAAAVVAAFPHIQRCTVMDLPHVVAEAPAGTAGLSFHGGDMFEHIPSADALMLKWILHDWDEDKCIKIMERCKEAIGGKEAGGKVIIIDTVLGSRADDDDDDKTCRETYVLDLHILSFVNGAEREEHEWRRIFLAAGFRDYKITHTRGIPSIIEVFP
The following text describes a protein:
Function:
Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Domain:
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
Sequence:
MPGRAGVARFCLLALALQLHWPLAACEPGWTTRGSQEGSPPLQHELIIPQWRTSESPGRGKHPLRAELRVMAEGRELILDLEKNEHLFAPAYTETCYTASGNPQTSTLKSEDHCFYHGTVRDVDESSVTLSTCRGIRGLIIVRSNLSYIIEPVPNSDSQHRIYRSEHLTLPPGNCGFEHSGPTSKDWALQFTHQTKKQPRRMKREDLHSMKYVELYLVADYAEFQKNRHDQDATKRKLMEIANYVDKFYRSLNIRIALVGLEVWTHGDKCEVSENPYSTLWSFLSWRRKLLAQKSHDNAQLITGRSFQGTTIGLAPLMAMCSVYQSGGVSMDHSENAIGVASTVAHEIGHNFGMSHDSAHCCSASAADGGCIMAAATGHPFPKVFSWCNRKELDRYLQTGGGMCLSNMPDTRTLYGGRRCGNGYLEDGEECDCGEEEECKNPCCNASNCTLKEGAECAHGSCCHQCKLVAPGTQCREQVRQCDLPEFCTGKSPHCPTNYYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPALDLCFERVNAAGDTYGNCGKGLNGQYRKCSPRDAKCGKIQCQSTQARPLESNAVSIDTTITLNGRRIHCRGTHVYRGPEEEEGEGDMLDPGLVMTGTKCGHNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNKNCHCFPGWSPPFCNTPGDGGSVDSGPLPPKSVGPVIAGVFSALFVLAVLVLLCHCYRQSHKLGKPSALPFKLRHQFSCPFRVSQSGGTGHANPTFKLQTPQGKRKVTNTPESLRKPSHPPPRPPPDYLRVESPPAPLPAHLNRAAGSSPEAGARIERKESARRPPPSRPMPPAPNCLLSQDFSRPRPPQKALPANPVPGQRTGPRSGGTSLLQPPTSGPQPPRPPAVPVPKLPEYRSQRVGAIISSKI