lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Sequence:
MEWVVATKMQAVEMAKVILQGRDEELAFRLQVEETVRVSVMEASEIRVNLEQCQSDSGSHANWDVNFDAALEVACQELETFVEQLEETLLSVIEINRLAHLEEGTQFVLVTDEVVDDQFETYVIQTMEFWCPKTSGLSCHDERKSRRRVQSSEPGTSRNRGLKLRVYHSGMEQDGKRKRILEDSSDEELLESFFRMAQLEDDRGANQADDEDTQNLCQICFDATPEQRPFITLNGCGHQYCQQCVSSHAMTLIANGKIHITCLQVKCPSTLSRRQLTSLLDKKTLDILISRRRESYIPASEIIYCPFKDCLKMATKPSTHGQQPQTSSDQHPSDFSKVKCGACHRAFCFQCNIAWHEAMSCGEYNASQKNQRLLGDEKLLMMAAESKWQRCSKCGTVIERSGGCSHMQCRCGHNFCYGCGVSWQGAGVNCMCP
The following text describes a protein:
Function:
Important for mitochondrial DNA (mtDNA) stability and repair. Recognizes and binds to base-base and small insertion-deletion mismatches in mtDNA. ATP binding and hydrolysis is crucial for function. Binding to a mismatched base pair attenuates ATP hydrolysis. Also involved in proper sorting of mtDNA during mtDNA transmission.
Miscellaneous:
MISCELLANEOUS: Present with 1670 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MKHFFRLPTAFRPISRVSLRYSSTDTAQPKISKLKISFNKISESNSEKKDNLGSIDTRNCLSTQQDDKLSSTEPSKASLPPSLQYVRDLMDLYKDHVVLTQMGSFYELYFEQAIRYAPELNISLTNRAYSHGKVPFAGFPVHQLSRHLKMLVNNCGYSVTIAEQFKKKDVADNEANKFYRRVTRIVTPGTFIDEAFENLRENTYLLNIEFPENCMSQVADTSLKVGICWCDVSTGEIFVQQVYLRDLVSAITRIQPKEILLDERLLEFHIESGTWYPELVELKKFFIKYQKMPSQHRTIESFYGLFNLGGKEATERQLKIQFQTFTQKELAALRNTLIYVSNHLPDFSINFQIPQRQLATAIMQIDSRTSTALELHSTVRDNNKKGSLLSSIRRTVTPSGTRLLSQWLSGPSLDLKEIKKRQKIVAFFKDNRDITETLRTMLKKVNDLSRILQKFSFGRGEALELIQMARSLEVSREIRKYLLNNTSLMKATLKSQITQLTESLNFEKNLIDDILKFLNEEELAKSQDAKQNADVTRMLDIDVKDKKESNKDEIFELRDFIVNPSFNTKLRKLHDTYQGVWQKKTEYNALLKGFFVGDLGAKTFTLKERQNGEYALHVTGTASSLKKIDELISKSTEYHGSCFHILQKSSQTRWLSHKIWTDLGHELELLNLKIRNEEANIIDLFKRKFIDRSNEVRQVATTLGYLDTLSSFAVLANERNLVCPKVDESNKLEVVNGRHLMVEEGLSARSLETFTANNCELAKDNLWVITGPNMGGKSTFLRQNAIIVILAQIGCFVPCSKARVGIVDKLFSRVGSADDLYNEMSTFMVEMIETSFILQGATERSLAILDEIGRGTSGKEGISIAYATLKYLLENNQCRTLFATHFGQELKQIIDNKCSKGMSEKVKFYQSGITDLGGNNFCYNHKLKPGICTKSDAIRVAELAGFPMEALKEAREILG
The following text describes a protein:
Function:
Responsible for physiological and behavioral changes in mated female flies.
Subcellular Localization:
Secreted.
Sequence:
MKAIIVFILFISSVHAMSKCNQAIYLNLDPHCGILPDCNLDGPNPSYLKRVSCERKENGKPGFIELIPGKCLHGKPRCSLK
The following text describes a protein:
Function:
May play a role in cellular stress response.
Subcellular Localization:
Cytoplasm.
Sequence:
MAAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNAKYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDHSKFWAYADYKYFVSLFEDKTDIFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHTVTLSPGQVRERKWQEGTQLLLLVKRRMDFGGRQSTRVIFIKVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVCALKTAENPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELNVCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDKDGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTKAPSQTFISTDDLLDCLVNPQVTRMVAQLLIQGRSL
The following text describes a protein:
Function:
May be involved in vacuolar sorting and osmoregulation.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MKCYNPSAFVPMAVTLVTVVIYLGVFIPLLIIHETVPSAPDDPTLYNGLNLTEAWLDLQSLSDGYHPFNSRKNDDVRNWLLKRIDEILDHNQIQYTTENETADTSDVQLESDFDKDVPESMSGPNNFNDDSVEYHEDLRTRKVSPAVTVFNDLRSNYSSNALTSIGVKGRRLGISTYFEGNNIICYVRGNDDEEGEWWKTGSVNSKGKMHGRGGVMVNAHFDSVSTGFGATDDGVGVVTALQLIRYFTTPENRPQKGFVALFNNGEEDGLYGAKAFLSHPMAKFVHTFLNLEGAGAGGRATLFRSTDTEVTRAYAHAKHPFGTVVSSDGFSSGFVRSETDYVVFRAEGYRGLDVAFWQPRSQYHTDQDDAKHTSIDSLWHMLSASVATTRSLTRDTSNTFVGPRSDDKIGKVSNGKGSDGVWFDIFGTVFAVFRLRTLFAWSLTLLIASPLILFAVSYLLNRQEKFYFFAGSIKSKNPEDEPISLGGWRGAFRFPITLFITSAITFACASLINKINPMIIYSSPYAVWSMSATLFFSVFWFIMAGCNFVRPSALQRGYAFMWMFVFGWILLVVATVYEDRFKISGGYLFVFYEAAIFLATLIAICEQFALPRKSTYIEDSQNDHSDNQDHHHQAVMGTDGANGADEPNADDEAAEEDQEETVNATAFPHETTPLIGGGQPSHRASVSTSFANRYRQVVPESYDGPADHDDKKGHKKHPYGGEQEWSAKLPIWTWLVQYLLVGPFILVILGQVGLFLVAALHQTGTDGSPLFLPYLIVAIFSILLLLPVTPFIHRLTHHMPTFFFLVFIGTLIYNLVAFPFSPNNRYKAYFQQTVDLDTGVNRVTLVGIEQYIRNIITNIPSAAGQSINCEANPRIRSGLSFCSYEGIPPQVVDNVVEGVPPEKGYSDWLSFNVSRVPNENKATFHISGVETRACILRFDDPFSEFKVHGGAKSEERWDDVPDSGSDQIKLWHRDWNKEWVVDVEWAVGEDMKPGDEGRSGRVVCLWSDANKRGVIPALDEAQRFSPQWTSVVKLMDGLVEGSKRRVGELVRVGGWKKGRRDDFSLALGLAFLLAYV
The following text describes a protein:
Function:
Acts as a Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms. Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity. Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects; Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane.
Sequence:
MEPVKRVAVIGAGVSGLVSVKACLEEGLEPVCYERNDEIGGIWVYRDKNPNGQTDAAIYEGLVTNSSKEMMCFSDFPFPREWAPYIQGKQLNEYYHAYAKQFDLNRHIHLNTEVLCVEKTKDHDTTGRWSVLVRNQDGTESESLFDAVMVCTSIFNKPFVPTYPGMDVFRGETCHSKDFRKGERFEDKTVLAVGGSHSAGDMAVNSSRFAKQVYLSTRTGTWLANRMQSNGLPRDMTIHRRYMTHVPVNWKLKRFEQDSVQRVDPTLIGIRSSKRYGTTTVMINDDLGTMVLSGKIKTKPGIDHFTETGVVFKDGSTIEELDAVVFATGFQICNPYISHDIVPDRLEDLEMFHFVWPAKEKHHTLAAIGFIMIVGPHAPALELQARWAVQVFKKNVGLPPREVMMKEITGRKMGTFKRFGKHKIQTLPLPYQDIIAGFIGARPDLRSLIFSDPWLAYELFFGPAYPAGYRLFGPHTWSKAREHIARGIDNVVFPTKTRSVETAQSAGSIFRLTVNGFLKTAFMALMIIFILSVLT
The following text describes a protein:
Function:
Involved in the biosynthesis of theobromine.
Sequence:
MEVKDIVFMNKGDGENSYVKSAGLTLKVIAKTQPMVQKAVQSLFKGTHSAPLQVVNVADLGCALAPQPLESMSIVIESIVEKCGELGCEMPEIQFHFNDLAGNDFNTLFKGLSVVQEKYKNVSWFAMGAPGSFHGRLFPRNSMHLVHSCYSVHWLSKAPKITSEEGLPLNKGKIYMSKTSXXXXXXXXXXXFEEDFSSVLRFRSPELAPDGRMVLILNGRQSADPTEKDICYLWDLLAEALSYLVSEGLIDEEKLDSFNVPYYNPSQEEVERVIDKEGSFTTEFSDTVVLEIGGKNAWSDPGLRIKGYRCFSEPVLSHQFGEEVMDKLFDKAEEILAEDYKQGKEATKNISIVVVLKKKTNQTWT
The following text describes a protein:
Function:
Plays a role in type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. Substrates include proteins required for biogenesis of the type II general secretory apparatus.
Miscellaneous:
MISCELLANEOUS: Part of a cryptic operon that encodes proteins involved in type II secretion machinery in other organisms, but is probably not expressed under laboratory conditions. However, GspO is functional when expressed from a stronger promoter.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTMLLPLFILVGFIADYFVNAIAYHLSPLEDKTALTFRQVLVHFRQKKYAWHDTVPLILCVAAAIACALAPFTPIVTGALFLYFCFVLTLSVIDFRTQLLPDKLTLPLLWLGLVFNAQYGLIDLHDAVYGAVAGYGVLWCVYWGVWLVCHKEGLGYGDFKLLAAAGAWCGWQTLPMILLIASLGGIGYAIVSQLLQRRTITTIAFGPWLALGSMINLGYLAWISY
The following text describes a protein:
Function:
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
Subcellular Localization:
Cytoplasm.
Sequence:
MKFFITGTDTGVGKTYVSTLLLHQFNNKGFSTFGIKPIASGCRKINNKLHNDDALALQKVASIKTTYEHVNPIALEPPIAPHIAAKLNNQVLSKNDLAKTINQIFNLPADVFIVEGAGGWFVPLNEKEFLSDLVKLLKIPVVLVIGIKLGCLNHAFLTAKAMLREKIPLVGWVANCIEPDVLAMAENIQTLKKGIKAPCLGVIPYDGTVEDLSIQPLLDHFNKVVSPEENIRSEPSESWTVK
The following text describes a protein:
Function:
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Involved in the regulation of lymphangiogenesis.
Subcellular Localization:
Secreted.
Sequence:
MWQIVFFTLSCDLVLAAAYNNFRKSMDSIGKRQYQVQHGSCSYTFLLPETDNCRSSSSSYVPNAVQRDAPPDYDDSVQRLQVLENIMENNTQWLMKLENYIQDNMKKEMVEMQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVLDMEDKHIVQLRSIKEEKDQLQVLVSKQNSIIEELEKQLVTATVNNSVLQKQQHDLMETVHNLLTMISTPNSAKNSFAAKEEQIIFRDCAEAFKSGLTTNGIYTLTFPNSTEEIKAYCDMETGGGGWTIIQRREDGSVDFQRTWKEYKAGFGNPSGEYWLGNEFVSQVTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEEFNYRIHLKGLTGTAGKISSISQPGNDFSTKDADNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF
The following text describes a protein:
Function:
Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate. The mechanism proceeds via the intermediate compound alpha-D-glucose 1,6-bisphosphate. This enzyme participates in both the breakdown and synthesis of glucose.
Sequence:
MVFKVSKVSTTPIDGQKPGTSGLRKKVKVFIQPHYLQNFVQSTFNALTPEKVRGATLVVSGDGRYFSKDAIQIIIKMSAANGVRRVWVGQNGLLSTPAVSAVIRERVGVDGSKATGAFILTASHNPGGPHEDFGIKYNMENGGPAPEAITDKIFENTKTITEYLIAEDLPNIDISTIGVANFSGPEGQFDVEVFDSASDYVKLMKSIFDFELIRKLLSSSKFTFCYDALHGVAGAYAHRIFVEELGAQESSLLNCVPKEDFGGGHPDPNLTYAKELVARMGLGKSDSAVDPPEFGAAADGDADRNMILGKRSMPTSAALDVVAKNLNLKFFEVPTGWKFFGNLMDAGLCSICGEESFGTGSDHIREKDGIWAVLAWLSILAFKNKENLNGDKLVTVEDIVRQHWAIYGRHYYTRYDYENVDAGAAKDLMAYLVKLQSSLDEINSSVKGARSDVSNVVNADEFEYKDPVDGSVSKHQGIRFLFEDGSRLVFRLSGTGSEGATIRLYIEQYEKDSSKTGRDSQEALAPLVVVALKLSKMLEFTGRSAPTVIT
The following text describes a protein:
Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity).
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MVLLRLLVFLFAPVVSDLCSLPCFINVSESQGPGTVLQFLSFNCSSYTPTPTLELLNVQPPTTFFNPPSLARWQGTYVGKLTLSSSAQLDALMVNHYKVQLKFTCGNHVMEGSLSVDVQRDLSHIQCAGQFASPAGEMIQVPETVTPGARLYTLLLPGLELHGAQMSIISAQDLPHFPGPFSINEQGWLQAPSQGLLGQAQKVFQLQISVSFGQRQSCQGMVIVKVLPVPSSQVSFLEQAQNITIPENLAPGSEVVQVQARGVDLRYEILSPVPSPLFSIGRADGVVRTTTPLELARTSGTAVSRLQVKAFEQGQLWASAKLNLTMNVQLVNLWPPRCLPALLVSQIPETAPVGTVLNTLTCEDPDSVGATLDYKLWFRSSSNPASLCLYDRVLEVNATLDCDTPGACFQHAASILVLDGGQPQMTTEVPVLVMVTPINEFSPACAPRTFRVQEDAAPHTLLGSVVGTDMDYPHDNIEYYTSGGPTTFAVDRLSGEVHLLGPLDYEQQRLYRLTVLVIDHGQDQNPNHHLSGSCTITIEVEDVNDHAPECEPPFQELTIYAPLGRSVEVTKMSCQIPQEPQRLIYSYSIVGGNSQNRFILQGAILVHSDLVLGPFWPEQPRTYELLICVADAGPSTPHLSTTATIIVHLVPRRASTVATSTHRTTVPSTMTPMLVTDTEAFWQPQPWFVVVLTATGALLLLALGWLLGRLLQGLAQLLQAPSKPAQALLLNSIQGTEGSIEGFLEAPKMEMSQAPSSVMSLHFDGRAQDSRTGRDYLFNTHTGARRWL
The following text describes a protein:
Function:
Has a role in establishing cell polarity. Also required for maintenance of cell wall integrity, sexual differentiation, calcium tolerance and cell morphology. Involved in Ras-MAPK signaling pathway at cell cortex. Has a role in meiosis.
Subcellular Localization:
Cytoplasm. Note=Localizes to the septum and cell cortex.
Sequence:
MSSSSVSNTLSIETKSDPKDPAFVASQESTECNEHDTTQLSGSSSEPLENNSSLTRSTDDPSVEIRSKLVSPDNEANLLSDQNITISNENNNENDTTEEAETSSGNEAADDEDSSSDAQSSVPSFSEIHDGMSEEELDKERKTLTHLRRISLQGADDPEIPTDWSVAMSPPETEQDASTLFWVPANLHPELNPTGWKSFLDLQVKNLKSPTATDTSSSPLEHIRSLRRRKSLLSRQVKADDAVINYQDGSPIVEKAYLKRHRSLRLNELEHLESLARDPHRMVSLVDGMSNGSPEDSPLLVSPNHFLQRSSRTTIRRTGASIRTIHRGKTSTLSGNRSHSILQKPTDTSPLHKIEPISADELVESDDSRTSALSNSQNPSDDVENQSDQALEVLSLTNPPKIDNASADTTLHKETNKIDKLYVSENKAESAVASESSLSEGTLALKAPAPENKPEKSSTSKPPVPENKAEDSVVLKSSVPEDKSENSIASKPSATEGIPENAIALQSSVPENKAEDSVVLKSSVPEDKSEDSVPSKSSVLEDKHENSVEIDKKADDSLPSNNKTEGYTPSVVREEKNYSEPNASPSVIPPRVPTPVPGRTLSPKPTRIPTPIPSSLNVSLESSKKPEIFHERHIPTPETGPNKPSKNNILKSTQVPVTPKQKSSTANKGSTSSPSPPSSESKKTKRSWGRLFVSGDSDKEHKEHKKDKQKKKNDQISSSSKSASSFKKDRDKESIFGSLFGSKKKQTEIPPVSSSPPHNDAPPKAKPISAPSELPNTTSVAEAKCQTVTDDEGTDQQSDEKSTEPKTFIPDKDYYWSRFPICTERAIYRLSHIKLSNAHRPLFQQVLLSNFMYSYLDLISRISSNRPMNNVQQSTAKPIRKDINGQQRRSEFSAENVKNELENLSYQFGDQRKRNLNRKGSTIHTVSQNIQKVSKNAK
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.
Subcellular Localization:
Cytoplasm.
Sequence:
MAIKLLIDNPKQVKPIKSYLEDHNWLNKSFKIQKKNDIFHIFTNLNEIPSQLSQYNHETYEQEDDGDLNTKNKTTTLTLASIITDYCHANNIENIEIPKRWSIYPPMILFNSTGSTSESNGHPTSDTIFNPQHQKLWENVLSNQKSIFGTSEITHIALNKPIIESDIMRRPHNLIPIIGDFGPDISIDNKPPSPTESDFNRAFWCHVIQNGIYQTWAPKYTMFSRGNIKEKKRVLDWFKNLDQTIVFDFYCGIGYFSLSYLKNGGKLLCWELNPWSIEGFRRSLEKMKINYKIYTSGDKFSINDLNQFDACLFLESNEQITTRVIDQVKDNSLPISHINLGLLPSSKQSWTLANNLIDKSTINTNVHIHENVHIDDFEKIKTDVKKVFTNGKVLHLEKVKTFAPDIWHIVIDIENIKSC
The following text describes a protein:
Function:
Acts as a catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MYGKKLDERDLDKVSNNPNHTKICREPPPNHEFSYRWFRGPTVEPCAYEGCPRRTSFSPHDWSKHALGGSGCSLQCVSTQSSLYKATFCNANCFVKAWKTQYTVQSDVPQARSSTPQRRRLGSYADDDDTRSVNSVNSGRSDYNPPGTPREITVGGNANTPRGNNGGYNDHHGQSEEWIEISRDQLYVPNENDVGRKLKLEAAAYAIDSGELLMHRVVKTDLVLSRTSELDKRNFITSKPSGGGGARFRIVTYNILAEIYATQQQYPHADLWSLSWDFRFQNIIREIVDVGPDIVCLQEVQADHYESHLYNAMHDAGFEGVFKQKTRQSMGMTGKVDGCALFWRRTKFHLIESYSIEFNELAQRQVTQVMGLNPRSEEGAAILSKLSKDNVAQLVVLELAQQSISRSSREPINQVCIANTHLYSNKDYPDVKLWQTLHLLQELETFIMARGTNLPLMICGDFNSTPDTAVYDLLSRQAVHPGHPDVNLGDDNGPNVLPDIMNITHSHMLGSVYNTVLGEEPKFTNYTMQFKGVLDYMWYSTQNLRPLSAAPIPDESVLTRYGDALPSTQYSSDHIMQISDMQIVSVGRPP
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MNLMLTLFTNATLASLLILIAFWLPQSYAYAEKVTPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQATNLNLVLFMALALITLLALSLAYEWIQKGLEWVE
The following text describes a protein:
Function:
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MANKIQVAISCVSALNLLIFIISALFQKFEKGPTISSTCDFSHAAVACDTETCSLVGRDILKDGGSAVDAAIATLLCIGVVHPQSTGLGGGAIFTIYENPVQGTVKVINARESVPKMAKKIEYGERKSIIKKGPQWIGVPGLIRGMEKAHSLYGRLPWEKLFEPAIKLAKEGVNVSEILSWYLNSPNLKNAVETSPLCHSGVLCDENETVLKTGDKMRAIALAQTMQIIAEKGASAFYNGSVTKTFIQDIQQNGGGITADDLESYRVQVTGVMKAQVGEYTMYMPPPPAGAALVSFVLNVMKGYNTNFQSVQGDQKLLTYHRYIEALKFANGQKKQIRDPEFNGWNDILRLISDEFADFVREMISPSETHPLPYYNITPGPSSDRPGTTHVAVIAEDGSVVSVTSTINDIFGSMVFSESTGVILNNQLTDFCGRAESINAVLPSSTLLFQQAGEKPPSSTSPVVLFSQSRNEILVIGGAGGSTITTSVVSVSTPYLNVPNSITNFVIQSLKHTLIFCSILQAIMNYLWWGKNLTSAVGTPLVYVDSKNRLHVEENDFFKSIKENLKKFGHTFMDTLLFENAVNAISKKGNCINAVSDPRGKEKPAGY
The following text describes a protein:
Function:
Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Required for correct segregation of chromosomes and for maintaining the inner centromere structure.
Subcellular Localization:
Chromosome, centromere. Chromosome, centromere, kinetochore.
Sequence:
MLVELLEFTPLSFIDDVINITNQLLYKGVNGVDKAFSQTRFAKKAPQEIEEGLHKFEVLFESVVDRYYDGFEVYTLRNIFSYPPELKGYMRTFGKDVDYSITTEQDAAMDQAIQEAAEKLVVKMQLRRDLRMRLSRKREKKTEIEKHLERISFLNKVPENWQVTLPETTDFLLDQLGNLQHAVKRVVEASPTVHSREVDERITYLEKGYERLSNPIDQQKDFWSHHLSKLESTANTETANNIHKLLLSSEKDVGHTDEP
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MHLIALSLIVCCSVSFSWANEWGYPDLDNNQDEPFPKWGGLCDSGKKQSPINLHVKGALKGEFDALKFENYDEHQKNLRMVNNGHSIQLSGFDHELTLSGGALLQDFVVEQIHMHWWSEHTINDIRYPLEVHIVHRNTIYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVKSYDSMNKPVLVADSLAVDDLVPSVENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEFKEIEYDEGKQLHNNYRELQSENNRAVVLVEQPEQRSGSAGLTASVSLGLMTLILAGQKFLL
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus.
Sequence:
MNRQSAGRASMSSMGSRRSSVGPLRVKHDNNAASTSRAAGNGFMRRSSGSSGTSAGGRKSTTSKSTFGFSNTRRPSSGYGRSNMAREVLRESRPISDKSYMQKEIRRIIEFLQENGFSNPISVKQLMSPTTKDFVRVFQFLFSFLDEDYVVGSKIDEEIPAKFKEMKYPFTISKSSMCTLGSSHAWPHILAALHWLFDSIQYAMNTSVAELLFTDEEMPGCLDEQAYSEVHFDYLENTYSEYMNGQDRYDVHETKLRNAIQTTKGGEVNMDNLVAEEERLQAELQELEQQQSRIPNLQEQMKAKTIDCERFSNYLVSLREHKKTHDLKMQEIDLHLGQMELEESELDGTMARLQYQLENQELSAKDVERMQTELRQANSSLDQVERENQALDQEIWAEERSIAKKQEELERKVNAYNSLARKLKLIPADAENAHGIDYELRLNFHSIHTQHSPMLDFVSTIKPALIQLKKNINSEVHKLHSQRLNEEEAHDQVKEMTEGKREEIRKLDSQVQRLEKDVNAFKEKTRDETQAMTARLSDIEQQKEMARASGSTDIAQTQEQVRQMQSRYEEGCQNMQMERENYNKFLTQVCTMILEHKTKLQNHVGHLQQEAHNHLEVIRGMEFPQHPNPST
The following text describes a protein:
Function:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Binds specifically to double-stranded DNA.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MTDGHLFGNILLAGRGGTKPGQMRVHSGGIAWKRQGGGKVIEVDKADIAGCTWMKVPRTYQLGVMVKDGLCYKFTGFREQDVSSLTSFIEKSFGVTMEEKQLSVCGRNWGGIELNGNMLTFMTAGKHAFEVSMADVAQTQLQGKNDVFLEFHVDDTTGANEKDSLMDMCFHVPNSNTQFVGDENRTSAQVLMEQIAQKADVGSSSEEAVATFDGIAILTPRGRYTVELHLSFFRLQGQANDFKIQYSSVVRLFLLPKSNQPHTFVVITLDPPIRKGQTMYPHIVMQFETDNVVETSLSMSEEQLTTKYKGKLEEHYKGLIHEVFTMILRGLSGAKVTRPGKFRSAQDGYAVKSSLKAEDGILYPLEKGFFFLPKPPTLILHEEIDYVEFERHGAGGSSSMSSHYFDLLVKLKNQQEHSFRNIQRNEYHKIFEFMKDKGLKILHIGDAQTSNGVAAVLADDDDDAVDPHLERIRNQTGAEESDEEDEDFVAEKDDGGSPTDDSGGEESDASESGGEKENIVKRDPKKEVVMPRASVKKKIKDDGEAEGSKKKRQKKKKDPNAPKRAMSAFMFFSNTERDNVKKSHPGIAFTDIGRILGEKWKKFTADDKKIYEDMALKDKKRYVEAIANYKVSTSTSAVPMNIDSGIDDSN
The following text describes a protein:
Function:
Required for the utilization of the prevalent host lipid lysophosphatidylcholine (LPC). Functions as a lipase that cleaves exogenous LPC and generates free fatty acids, which are then transported into the cell by fatty acid transporters such as FadL, and used in various metabolic pathways.
Subcellular Localization:
Cell outer membrane; Lipid-anchor. Note=Surface-exposed.
Sequence:
MKQVIKLSLLCSALWLAGCGDETNSSGASTEVVYESYIQQALQRDTTIKFALSGKDANVPLPSFALMNAKDGTLEIPPGSNTSGSNPLVAMGQVDGWPITMPLFLDFKGAGLADNIITSGIYLYELTDSMTGSPSIKALLTNGVDYTAVSSAASDKILIMPTKALNASSEYILAVTSEVSDANGNPVGTSASYAALKSKNKIYSEGDIATLQKVTQGVEKIFQLSGVDETQIVYSTWFSTQSVSNTLFATRGATASAFASGSNQLETVWKQTGLGLDTAYTIQLGTPVDFAAALTADDNFSTYVGADKKTAILGTYTANTVDVTKGTVRLPYYLETGSNWNTQPFESAMPSLAKIKAALADSKEQLTIGSQLLAAGIDTTKLATDASEQLKLMGLTLTKSDGTALDPERYITRYSPVPKVKSVQDVPFLLFTPAGAAPTDIVIYQHGVTTAKENAYAFAKNLTAVGLAVIAIDLPLHGERSLDSTRSANSDPLAYINLTYLAVARDNLRQSILDVLGLRAALTLSQPLFTGTRLSGINVGTGSKVRMLGHSLGGIVGTSAIAESNKTLGSTAADAMYSFSGAAIQNSGGQISNLLLGSAFFGPKIKHNVALSASTEYKGFADAQCASLDDSACYNLFTSLATQEQLAQVTSGFQMFSYAAQTLLDTIDPYSVVSTKLNNGGLTTPLYFSEVDGDSVVPNKVSNPTGSLVYLSPQFAGTEPLATLLGLTTVNAGQTAPNATKSFVQFNSTAKHSTFVAPQDAGYADLAHHTEMQTETADFLADDSLGAVSNSNSVLK
The following text describes a protein:
Function:
Involved in peroxisomal fatty acid beta-oxidation. Required for wound-induced jasmonate biosynthesis. Possesses enoyl-CoA hydratase activity against short chain substrates (C4-C6) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C16). Possesses cinnamoyl-CoA hydratase activity and is involved in the peroxisomal beta-oxidation pathway for the biosynthesis of benzoic acid (BA). Required for the accumulation in seeds of benzoylated glucosinolates (BGs) and substituted hydroxybenzoylated choline esters, which are BA-containing secondary metabolites. Required for salicylic acid (SA) in seeds.
Subcellular Localization:
Peroxisome.
Domain:
The epimerase and isomerase activities are contained in the N-terminal region while the dehydrogenase activity is in the C-terminal region.
Sequence:
MAKKIGVTMEVGNDGVAVITISNPPVNSLASPIISGLKEKFRDANQRNDVKAIVLIGNNGRFSGGFDINVFQQVHKTGDLSLMPEVSVELVCNLMEDSRKPVVAAVEGLALGGGLELAMACHARVAAPKAQLGLPELTLGVIPGFGGTQRLPRLVGLAKATDMILLSKSISSEEGHKLGLIDALVPPGDVLSTSRKWALDIAEGRKPFLQSLHRTDKIGSLSEARAILKNSRQLAKKIAPNMPQHHACIEVIEEGIIHGGYSGVLKEAEVFKQLVLSDTAKGLVHVFFAQRATSKVPNVTDVGLKPRPIKKVAVIGGGLMGSGIATALLLSNIRVVLKEINSEFLMKGIKSVEANMKSLVSRGKLTQDKAGKALSLFKGVLDYTEFNDVDMVIEAVIENIQLKQNIFKEIEKVCSPHCILASNTSTIDLDVIGEKTNSKDRIVGAHFFSPAHLMPLLEIVRSKNTSAQVILDLMAVGKAIKKVPVVVGNCIGFAVNRTFFPYSQAAHMLANLGVDLFRIDSVITSFGLPLGPFQLGDLAGHGIGLAVGPIYAKVYGDRMFRSPMTELLLKSGRNGKINGRGYYIYEKGSKPKPDPSVLSIVEKSRKLTNIMPGGKPISVTDKEIVEMILFPVVNEACRVLDEGVVIRASDLDIASVLGMSFPSYRGGIVFWADTVGPKYIYERLKKLSETYGSFFKPSRYLEERAMNGMLLSESKSSRSKL
The following text describes a protein:
Function:
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
Sequence:
MNRKGNMKRKTLKNIVEYDGIGLHKGEIIKMKLIPAKSGGIIFRMVNMPEGKNEILLDYRNIFDLTRGTNLKNEHGAMVFTIEHFLSALYVLGITDLVIELNGNELPICDGSAIKFLDLFQESGIVELDEYVEEIIVKEPIFLSKGDKHVIALPYPDGYKLTYAIRFEHTFLKSQLAEFEITEKNYRKEIASARTFGFDYEVEYLKQNNLALGGTLENAIVIKKDGVLNPDGLRFDDEFVRHKMLDIIGDLKILNRPIRAHIIAIKAGHLIDIEFAKILDNIK
The following text describes a protein:
Function:
Involved in miRNAs and siRNAs biogenesis and thus promotes gene silencing. Modulates auxin (IAA) transport-related developmental programs by regulating protein phosphatase 2A (PP2As)-driven auxin efflux carrier PIN proteins recycling and polarity. Required during development. Necessary for abiotic stress (e.g. chilling and salt) tolerance.
Subcellular Localization:
Nucleus. Cytoplasm, cytosol. Note=Colocalizes with miRNA biogenesis components in distinct subnuclear bodies. Localized in the nuclei, excluding the nucleolus, in all cells of the root apical meristem. In young cortical cells of the root, localized in the nucleus and cytosol.
Sequence:
MEDSEKRKQMLKAMRMEAAAQNDDDATTGTETSMSTGHLSNPLAETSNHQQDSFETQRFDYYTDPMAAYSSFKKNKTPKQQYISSPSHQGSSPVPPQFPPSVPPGSLCSEYQAQTNHGGFHAAHYEPRGMAHLSPSHRGPPAGWNNNFRPPPVNHSGPPQWVPRPFPFSQEMPNMGNNRFGGRGSYNNTPPQFSNYGRQNANWGGNTYPNSGRGRSRGRGMNTSFGRDGGRRPMEPGAERFYSNSMAEDPWKHLKPVLWKNCSDASSSSSTGQAWLPKSIAPKKSVTSEATHKTSSNQQSLAEYLAASLDGATCDESSN