lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable transcription factor involved in embryonic patterning. Required for apical embryo development after fertilization. Its specific localization to the apical daughter cell of the zygote, while WOX8 is confined to the basal cell, suggests that the asymmetric division of the plant zygote separates determinants of apical and basal cell fates.
Subcellular Localization:
Nucleus.
Sequence:
MENEVNAGTASSSRWNPTKDQITLLENLYKEGIRTPSADQIQQITGRLRAYGHIEGKNVFYWFQNHKARQRQKQKQERMAYFNRLLHKTSRFFYPPPCSNVGCVSPYYLQQASDHHMNQHGSVYTNDLLHRNNVMIPSGGYEKRTVTQHQKQLSDIRTTAATRMPISPSSLRFDRFALRDNCYAGEDINVNSSGRKTLPLFPLQPLNASNADGMGSSSFALGSDSPVDCSSDGAGREQPFIDFFSGGSTSTRFDSNGNGL
The following text describes a protein:
Function:
Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MADHENEAEQESGDVSYFSSMLFTDQQYQPMVFFMRPSATRARLKLLIESGGGRVTSRHDPSEGDVIKILADGDEHSSPDCLLPSYIDDCVAANSLLDKFSYRAKSSTKEEQSTSVSEVTVSVSTKGRSYYTAAEDKAILEYIAKHPYQYCGNKTWQRMEIMKITNHSWQSMRDHFLKKLEGSLNKYTKKREENLLMKQQTDPDSDEDMSNSNDEDSNEREIKLSSDVAQTEENTAVEQHSDTSSFDMDLFQAASEDLKDKNADDRRDRGIEDGTTSSPRRTTSSPKRTTSSPRCTTSSPKRTTSFPRRTPRHTTSSPRRTTSSPRRTTSSPRRTTASPKHTTLSSRPTPRRTTSSPRRTTSSPRRKTPSPRRTPRRTTSSPRRTPRRSTAASSSDENQSQQTDRPVVHDHVVQRSTRQTKKEKDDATTTSTTKYSYKTRSKSDGMHVRDEKIVVGRKQGIERKAKNQRDSCHKEKHDVDRRTRREQILENQNKKAGEESDVKERNNVEMDSVGVQNGGTDDDGKQSGAMQVDEIDDGAMQTEGNGKEDISTHGRSSKEDFSTPEKIVVVRLSSAKKRKTPFKLKFGTDSIESQKEPTQPRQLPIVDSSSNRRTSSRRLRRGIEIVSDSSASEETMSDVLPMKRTRYTSTPHRNTSTELDNSDQPSDTQVEGTDLDNSDQPADTQADEETSLEETEDCINLIEELCTKYSQTKSKICTALYVNSGDVTKAEEYLQCSSQTNGPLWCSSQDKILLSSSCEQNTSMKYSKAVVSQRIKWLQS
The following text describes a protein:
Function:
Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic activity towards PtdIns(4,5)P2. Able also to hydrolyze the 5-phosphate of inositol 1,4,5-trisphosphate and of inositol 1,3,4,5-tetrakisphosphate. Regulates traffic in the endosomal pathway by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with endosomes. Involved in primary cilia assembly. Acts as a regulator of phagocytosis, hydrolyzing PtdIns(4,5)P2 to promote phagosome closure, through attenuation of PI3K signaling.
Subcellular Localization:
Cell projection, cilium, photoreceptor outer segment. Cytoplasmic vesicle, phagosome membrane. Early endosome membrane. Golgi apparatus, trans-Golgi network. Membrane, clathrin-coated pit.
Sequence:
MDRLEQVPSGGVSAIELKSGCKEPCLLILSQLHDGQYALVIHNQGKNSVSEDILPITSNFKFVQEAEETLLIDIPTNSGCKLRVQADPWSIERRFEIPDEEKCMELLAEMRHVQEGLVRHSQSEKKESSNWYQPGNKTDDTAGTSSKEPTQGTGTLGFEDNFSSINLEKRRNIQNQQMGSRREPPPPPPPPVERPLPLDRERDSSGWEKPRVTHSMRKLFTPNPQSGQREGLIKHILAKKESEFVNIKNFRFFVGTWNVNGQSPDGGLEPWLQADSEPPDVYVIGFQELDLSTEAFFYFDSGKEQEWLEAVERSLHTKAKYKNVRLIRLVGMMMLVFAKNEHFKHIREVVAESVGTGIMGKMGNKGGVAVRFVFHNTSFCFVNSHLAAHVEDFERRNQDYKDICARLNFTVPDQNIPTLNIMKNDVVIWLGDLNYRLCKFDAAEAKSLILKNDIQTLLKYDQLNIQREMKNVFSDFTEGTISFIPTYKFDPKTDRWDSSGKCRVPAWCDRVLWRGINIMQLKYRSHMELKTSDHKPVSSLFSIGVKVVDERRYRKAFEDIVRMMDRMENEFLPSLNLSRREFIFERVRFRQLQKERFEIKNDGQVTCHFSFIPKLNDTQYCKTWLRAEPCEGYLEPEETVDISLDVYVSKDSVTMLNSGEDRIEDILVLHLDRGKDYFLTISGSYLVSCFGTSLEALCRIKRPIREIPVTKLIDLGEDSFSEKEKSALQMLPVETDESVDKPLKIPKEIWLLVDHLYKNACHQEDLFQTPGKQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCIDCSHDTRLCRQVISQLSRCHRNVFRYLMAFLRELLKYTGDNNLSANMIATVFTSLLLRPPPNLIGKQTPSERQRGINFILGFLLSVDEE
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MLTRPLLALSRPMALGALRPAVLVRTLTTAGPTTTVRSTPIITPSHLSTLSRSTPFVSNCTLSLLKRSFHVSSDARSAAKAEGKPKVSAYEKANMRLAKIGVFFQLSWYLGIILAALGLFGLVWYYLIMELVMPSGDVRIFNRAFKEIEKNEDVMRVLGGQLSSMGEGGGGRWGRNQPPVSKRGIDKYGREHIWMNFYVSGDINEGRAKLELVQNTDSKLSSERFVYRYFVVDIPGHKRIYIAGNAAEKMEKKKSTGWLGVNWGKSDDE
The following text describes a protein:
Function:
Endonuclease that cleaves polypeptidyl-tRNAs downstream of the ribosome-associated quality control (RQC) pathway to release incompletely synthesized polypeptides for degradation. The RQC pathway disassembles aberrantly stalled translation complexes to recycle or degrade the constituent parts. ANKZF1 acts downstream disassembly of stalled ribosomes and specifically cleaves off the terminal 3'-CCA nucleotides universal to all tRNAs from polypeptidyl-tRNAs, releasing (1) ubiquitinated polypeptides from 60S ribosomal subunit for degradation and (2) cleaved tRNAs. ANKZF1-cleaved tRNAs are then repaired and recycled by ELAC1 and TRNT1. Also plays a role in the cellular response to hydrogen peroxide and in the maintenance of mitochondrial integrity under conditions of cellular stress.
Subcellular Localization:
Cytoplasm.
Domain:
The VLRF1 domain mediates binding to the 60S ribosomal subunit.
Sequence:
MSSSPELRSVFTLCGDQTVSCGLREVSALLDQTDPPQPIPYTEDAVPRKTMSAGEVSDRMFCHACQCPFESREEQMEHYKLDWHRFNLRQRLEGRSAVTVEEFEKKTGTGDISSISGSDSSDSEDGDLGDEVAPVQTDCALDTDQPQSRLSAKVVFQNAEGQFLSLYRCILQSKKDNEEDLVSSLLKISNNTVWVILMTGGGHFAGAVFKGKEILQHKTFHRYTVRAKRGTAQGLRDSQNRSHTPKSAGAALRRYNEAALHKDIHDLLESWVDYLKEASAIFLRAPSYNKTIFFGGRGAPLDKKDQRMRILPFATRRATFSEVKRVFDLLSTLHVYQKETEISSILSPSRRLWKKKTPKPVSHPVPNTNVPAEGEDAKEESSGEDDSGTLETVEVTLGTLVLREHEIYPNKKKRRKRKEKREDSSSRETNEDKADDENMDEGELEVESDSKEMQRKSRGRRKPKGKKPQPEEGKLILELTQMFNYEVDESWEYSLRDALYTACKTGDIQSLRSLLHLPEDEESRRERTTEEDPASQSSDLLNKPIDSAGFTLLHVASAAGQKSVIRLLMDAGSDPANKTKKGQTPYGVAPEKDTRNVFRKYMAEHPHKYDYTKAQVPGPLTEDIESKKAEKKKAQKAARKQKEKEQKEEKVKKQQEEEEKKRFTALSDREKRALAAERRLAEHLATTGGALNNIRRCFLCGESLLGKIPFEYLDYSFCTPRCVQAHRKANAAARP
The following text describes a protein:
Function:
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.
Subcellular Localization:
Cytoplasm.
Sequence:
MDETPKTKLSGRALKPGMCNKCKVETPSIIVKRAEFCRSCFLDSVGHRFRGNLSKSSIPEGSKLMVAFSGGPSSRALLQTMNDYCRVDPENSRKKRKFPEFCVCYVDQSSILDSHASDASKITAIVNSYQRELFIVSLEAVFEEHAPALLKTHIGVDDTISASSSFNIELEKNAKKVDSRLLVQQMFGTLSSMTSKEDLLHYLTLHTLVREAKAQGCAGILLGDTATSVAINVISNTCKGRGLSLPADIMDSEWYQDVHILRPMRDILSKEIGIFNRLSKLETVAHSSLTTFMAPKASISRLSQDFIVGLEKEFPATVSTVARTAFKIQTNHLSKKQCPLCEGPVDSTDNFASIDSSAETPGYPCKPICETKPSFECCSDDKTTTACCAQNVNKNEQVNVYPLLCYACRNIAHDFPKQKTTQSPSPNQHDVPLPAYIAHNSFRRLSQNELRNQISDFLIEDDNSVSY
The following text describes a protein:
Function:
Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.
Subcellular Localization:
Nucleus.
Sequence:
MMAQALQGIQQQYAPSGLPVQKRYTKETAAQILQLDNMDSDTSPVRLIIKRKIVTYLKGREQFYNLHPRYLLAVSKSIDEQLYKDAESKIHYMDFETLEVRLNALLSRGSFGNSRYALASSASLPTSHSEQLGIKVTDSSIQNGRAVPGSVNPPPPARDISHNVLYSQVGFAPTSHHDEAAASFAHSSADKIKQGPESLANATDAPCVSSLPKCSPCIAGDFSGGVPTGHTKYHFPGDVHQVDSQQPSTSGSSSSVSAMCDRTANSTNNNRYSAGQVSSSLQCRECGKVLYTRSHPIEESDQSNITAGSHDLYIHDQSKIRTDIKRECGLEGCMQMDETCFCREKCSTLNTKFSYDQCSYIAADSGNCVSIREAVKGAEQTSNSTVSKPTSPTSDESSGKHHPAKRLRINSPRPVHADKTKFPKELQPAANGTDVSSETVHSETTALPTKSPSGCSLLDSNASNNMEIIRLPETAMQAEEGLCHGNGDIEMKELSCYGNGDIEMKEGLCYENGDIEMKNSKLSSVDQTSLVACLTATKKRGGSILYALTAEELRDHMKSLNQHICPSQMMTEEHPSGLPDQNTCNLCGMERILFEPPPRFCALCFKIINSTGSYYVHVENGIDKASICAKCHHLSTAKFKYHKRSNYAETDAEAEWWVECDKCKAWQHQICALFNPKVADEEVEYTCAKCLLKERDIGDITLLESPTVLGALELPRTKLSDHIEQRLSVRLEHERLQRARASGKDIEEVPGVEGLTVKVVSSAARVLQVQPRFRDFFKDGKYPGEFPYKSKAILLFQKNEGVDVCLFAMYVQEYGSDSPLPNRRHVYLAYIDSVKYFRPEIKSASGEALRTFVYHEILIGYLDYCKKIGFVSCSIWACPSTKRDDYVLYCHPTSQKMPKSDKLRSWYQNLIKKAVKDGVVVERNTLYDFFLQPTSDRKASISAACLPYCENDFWPGEAERLLEKKDDNTSQKKEPQVGRLMRVAKRDDRKGNLEDNLEDILLVHKLGEKMRTMKEDFIMLCLQRFCKHCHQPIVSGKSWVCTCCKNFHLCEQCHAEELSAPLKDRHPATTKQKHAFQRIEEEPLPDTDDGDPTMESKYFDSRIDFLKHCQDNQYQFDTLRRAKHSTMMILYHLHDSACSACHRTMDQRFAWRCLVCAGCTFCDSCYKQDGEKLHIHKLKQTDNQQVLPNYTLQDYLEGLVHASKCFCAARSCAFKLCFTMKKLFFHGVRCDIRNRGGCRKCIFMWKLLLTHAKHCGDGACSVPRCRDIKAFFMDKAKMIAGPPCAVEC
The following text describes a protein:
Function:
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MKSNTESLAWENLRYDLHSWIKEAISSMGYPTMTPVQASTIPLLSGNKDVVVEAVTGSGKTLSFVIPVLQKISDRLYKPDSDGDLPEPVKRGHMLSIVLSPTRELANQIQSVFNQVLQYLPEDKGTRINTQLLVGSIGNVREDLNQFLTNQPQILIGTPGRILEFLGSSQSIKTSSLEIVILDEADKLLDFSFEKDVINILKKLPKQRRTGLFSATISSAGNTIFRTGMNNPVKVQVKSKNYFGEQSNSPKSLQLSYMMINPELKITTLLTILSKYQYKKAIVYFPTCTSVKHFYQIFNKVYQQESSDEPLKFFSLHGQLNTKSRLKTLDNFTQGDINLYKHILMTTDVAARGIDIPDVDLVIQIDPPTDPNVFLHRCGRTGRANKVGRAIVMLNDNCQEEDYIGFMEVKGIFLTKQDIPTSSATKNLHENFQIKLRQYMLEDRARHELAVKSYVGFIRYYSKHIASSIFRLATLDYLGIAKMYGLLRLPKMPETKYIDNSIMPTDGWLGEIIDMDKYSYADKLQEKTRLENLENDKLKKIQDAKRRKELKIKNEAWSSKSERKENKLDRKEKLKRKREAIEKQIMEEERLNDGGNKDEEDEVVEDWKDMVRKNKKKQKKNNSIQGSFDDL
The following text describes a protein:
Function:
Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (2',3'-cGAMP) from ATP and GTP and plays a key role in innate immunity. Acts as a key sensor of double-stranded RNA (dsRNA), the presence of dsRNA in the cytoplasm being a danger signal that triggers the immune responses. Directly binds dsRNA, activating the nucleotidyltransferase activity, leading to synthesis of 2',3'-cGAMP, a second messenger that binds to and activates Sting, thereby triggering the antiviral immune response via activation of the NF-kappa-B transcription factor Rel (Relish) (By similarity).
Sequence:
MENILNDINKRFISLPEEDVRGNKQILESVLRTFVEQMKTQDPLFKALFRRVFYGGSFYDGLKVGKPEEFDLDILLHIPIYAQPVLNESNVPGFVWLKLNNLDGWLRQPEGRVYKDFRKKFLADNDFLDTGKTLRWMESLVQKTLNTLPWVNNATCELTNEFGTFHINWWKGGPAMTLGISHSSGEKIMDVDLVACFVFSGDKWPINGYRSNPFPSTKPEFFIVPKKPQGPVNPQGRYWSLSFQEQERVLIDNKNRLKPAVKLIKKLKEKTHPNIASYYIKTVFLHIIEQKDQSFWNKSLREVFMTTLREYNEFIADQSIPYYWCRKNNLIGHLAPITLNNISNRIGYIIKDIENNPENIAKHLLTKEEYTKYIQGEDVMAEALPALPASQTSSCVII
The following text describes a protein:
Function:
Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity).
Sequence:
MNFNNNNNNNNNNNNNNNLNNNNNNVNNINNNNKKPLTNSLAGTPPAKKILVIKNLKQIPKTPDNYEDSSWNKLSSAITSINMKQATTLTQEELYKMVENLCFDKILASNLYNKISVQIEKHITLTIKHLVLTMSSDPIIFLKSINSIWKDHTNQMIMIRSIFLYLDRTYVIQNSNTVKSIWDLGLFYFGNNLSQQSNLERKTIDSLLYSIRCEREGDEIDRDLIHSLVKMLSSLNIYTKFEIEFIKETNRFYDMEGNSKINEIETPMYLKYVCERLNQEGERLMRYLEQSTKKQLMAVLDRQLIERHVDVILEKGFNAMVNGDRLEDLGKLYQLLNSVGEIKKIKESWQSYIKQTGIQMLNDKEKEATLIQDLLDYKDRLDRILSQSFSKNELLTYALKESFEYFINTKQNKPAELVARFIDSKLKVGGKRMSEEELETVLNKSLILFRYIQGKDVFEAFYKQDLSKRLLLDKSTSIDAEKSMISKLKTECGTTFTAKLEEMFKDIELSNDIMNSFRDSPMTQNFKSIEMNIYVLTSGNWPIQPPIEATLPKEFLEYQEVFNKFYLSKHNGKTLKWQNALSYCVLKANFIQGKKELSVSLFQTIILYLFNDVIDGGELSFRDIQANTGLAIPELKKNLLSLCSSKSDILIQKKSSTSSNTSSNTSSNTSSSASGSASGGASGGATKTKVIDETDTFLFNSKFSSKLFKIKVNSIQIQETVEENQKTNENIISDRQYQVDAAIVRIMKTRKTLAHNLLISELVSLLKFQPKPVDLKKRIEILIEKEYLCRDPENAMIYNYMA
The following text describes a protein:
Function:
This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.
Subcellular Localization:
Nucleus.
Sequence:
MNSGGRGGKRRGPPPLAPSGAAAKRVNPSPGTPHVPPPASAAAAVEEDMMDEDVFLDESILAEDEAALLMLQRDEALASRLARWKRPAIPTDLAAGCSRTVAFQQLEIDYVIGESHKELLPSSSGSAAILRIFGVTREGHSLCCQVHGFEPYFYIGCPSGMGPDDISRFHQTLEGRMKESNRSSNVPRFVKRVELVQKQTIMHYQTQQSQPFLKIVVALPTMVASCRGILERGITIEGLGSKSFLTYESNILFALRFMIDCNIVGGNWIELPAGKYRKAACIMSYCQLELDCLYSDLVSHAAEGEYSKMAPFRILSFDIECAGRKGHFPEPTHDPVIQIANLVTHQGEDQPFVRNVMTLKSCSPIVGVEVMSFDAERDILLAWRDFIREVDPDIIIGYNICKFDMPYLIERAEVLKIAEFPILGRIRNSRVRVRDTTFSSRQYGVRESKDVTIEGRVQFDLLQAMQRDYKLSSYSLNSVSAHFLGEQKEDVHHSIISDLQNGNPETRRRLAVYCLKDAYLPQRLLDKLMYIYNYVEMARVTGVPISFLLSRGQSIKVLSQLLRKAKQKNLVIPNIKGQGSGQDTFEGATVLEARAGFYEKPIATLDFASLYPSIMMAYNLCYCTLVPPEEARKLNLPPEFVNKTPSGEIFVKPELQKGILPEILEELLAARKRAKADLKEAKDPLERAVLDGRQLALKISANSVYGFTGATVGQLPCLEISSSVTSYGRQMIEHTKKLVEDKFTTVGGYEHTAEVIYGDTDSVMVQFGVSTVEDAMKLGREAADYISGTFTKPIKLEFEKVYFPYLLISKKRYAGLYWTNPEKFDKMDAKGIETVRRDNCLLVKNLVTECLHKILVDRDVPGAVQYVKNTISDLLMNRVDLSLLVITKGLTKTGEDYAVKAAHVELAERMRKRDPATAPTVGDRVPYVIIKAAKGAKAYEKSEDPIYVLDNNIPIDPQYYLENQISKPLLRIFEPILKNASKELLHGSHTRSVSISTPSNSGIMKFAKKQLTCLGCKAVISGASQTLCSHCKGREAELYCKTVANVSDLEMLFGRLWTQCQECQGSLHQDVLCTSRDCPIFYRRRKAQKDMTEARLQLDRWDF
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
Sequence:
MVALILSINIIALDGRSDGSIVDYDIRKDDRAICDYRGHRLEVCSLKWSELFGRYLASGGKDKLVHIWDTRMAVANHHPRQHQLLHKISNHTSTVRALDWCPTRSNLLASGGGRNDHCIKFWNAVNGVSLNSIDTGSEVCALLWDKNNSELLTSHGFPNNQLTLWNYTSMMRKAELFGHSSRVLYLAGSPLGGVVASATEDETLKFWNVFETPKPPKPEANTVPFAQFNVIR
The following text describes a protein:
Function:
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs). May play a function in the positioning of chromatin fibers within the nucleus.
Subcellular Localization:
Nucleus, nucleoplasm. Chromosome. Note=Localized specifically on the chromosomal surface region throughout mitotis.
Domain:
The PPC domain mediates interactions between AHL proteins.
Sequence:
MVLNMESTGEAVRSTTGNDGGITVVRSDAPSDFHVAQRSESSNQSPTSVTPPPPQPSSHHTAPPPLQISTVTTTTTTAAMEGISGGLMKKKRGRPRKYGPDGTVVALSPKPISSAPAPSHLPPPSSHVIDFSASEKRSKVKPTNSFNRTKYHHQVENLGEWAPCSVGGNFTPHIITVNTGEDVTMKIISFSQQGPRSICVLSANGVISSVTLRQPDSSGGTLTYEGRFEILSLSGSFMPNDSGGTRSRTGGMSVSLASPDGRVVGGGLAGLLVAASPVQVVVGSFLAGTDHQDQKPKKNKHDFMLSSPTAAIPISSAADHRTIHSVSSLPVNNNTWQTSLASDPRNKHTDINVNVT
The following text describes a protein:
Function:
Virulence factor which promotes fungal virulence by enhancing type 2 inflammation in the mouse host. Likely binds mouse Tlr4 independently of Ly96/Md2 and activates Tlr4 signaling to drive Stat3 phosphorylation in interstitial macrophages, which promotes the initial induction of Arg1/arginase-1 and increases macrophage sensitivity to Il4 signaling.
Subcellular Localization:
Secreted.
Sequence:
MFSIPPSVRRLVFLFLIAAPLLSIVLPVAAAPAGVDPPSKLQPRAPQPSRRMGATKRSKKIEPLKKKDYSSFLCPGGSVACPIPGDEVSPSSVEALEKSLNSLADWFKVGFECVELETELNSCGGCLALGSGQDCALIENARTTGCENGSCQVYSCFDGYVVSPDRTSCVKRGSTIPATPVTAVNVEEFVADDQLPFGQ
The following text describes a protein:
Function:
Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Can also transport low-affinity substrates such as alanine, phenylalanine, glutamine and pipecolic acid. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWDQCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANVINEKCITQNSETIMKFLKMGNISQDIIPHHINLSTVTAEDYHLVYDIIQKVKEEEFPALHLNSCKIEEELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTFKVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVCFVYGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKASEEFLSYPTWGLVVCVSLVVFAILPVPVVFIVRRFNLIDDSSGNLASVTYKRGRVLKEPVNLEGDDTSLIHGKIPSEMPSPNFGKNIYRKQSGSPTLDTAPNGRYGIGYLMADIMPDMPESDL
The following text describes a protein:
Function:
CAP-1 and CAP-2, but not CAP-3 are ligands for the Capa receptor. CAP-1 and CAP-2 are probably components of the signal transduction pathway that leads to Malpighian tubule fluid secretion via the second messenger nitric oxide (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MKAIFSLYNIVSAILLLVLLAEFSTAELNHDKNRRGANMGLYAFPRVGRSDPSLANSLRDASDAAVFDGLYGDASQEDYNEADYQKRAGLVAFPRVGRSDAELRKFAHLLALQQVLDKRTGPSASSGLWFGPRLGKRSVDAKAFSDASKGQQEFN
The following text describes a protein:
Function:
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
Subcellular Localization:
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Sequence:
MQSTASSFHARAPINIKLIGLGGCGGNLVSTLKLQNDQVDLVVANTDLQDLAGRTTIPTRILLGPQQTAGKGAGGRPDVGAAATVESEPMLAKALSGADLVVIVAGMGGGTGTGAAPVVARLARQLGALTLAFVTMPFQVEKGQRSRIAEQGLASVSKEADAVVVVSNQKILNFVDPRTTLSVALTYSNTILAAAISGVIDQLSLPSLMQLDFSHVRQTLSQAGQTMLGIGSATGSDAAQRAMQLALKCDLLEGNLQKARRVFASIIGGSNLGLIDVHQAIEQIHRVVANEIDLVIGVATSPLASHRDRVRVTLIASEVASFRQSLSSGQANPKASVTHTISSNDLPPFLKLHRRGCL
The following text describes a protein:
Function:
Plays a role in odontogenesis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSASPAANTFGASAPPANMFDTVPGYEGTLAGGGGGYLPPPMPSVPMPVPEQAPHPPDWHIPSISEERAREAFATYVSSNCCYSSGPVTDGVITNMQSFNTYRYRLETFTESRSTEWSQEPYSGQPVDAGVQPAPGPWQIAAQPPPFFQDQKQAIKVPFTSSIKNCHVCLGMGNKPCTTCAGAGNKVCWVCNGSGSRLNDERCSHCNGQGRENCSSCSGNGSSQCDTCHGKRQLIVFINLNVKWSTEKEDFVAQDLSGLKVEKLEKVSGKELFKDSQFMVYPVMGFPDASVAQASQRIVRDHQTKFAQTSRILQQRQTIELIPVTKVNYTWKGNPYVYYVYGNEFEVNAEDYPATCCCSVM
The following text describes a protein:
Function:
Transcription factor that confers sensitivity to abscisic acid (ABA) and salt, but tolerance to drought. Regulates secondary cell wall (SCW) biosynthesis, especially in interfascicular and xylary fibers.
Subcellular Localization:
Nucleus.
Sequence:
MMCSRGHWRPAEDEKLRELVEQFGPHNWNAIAQKLSGRSGKSCRLRWFNQLDPRINRNPFTEEEEERLLASHRIHGNRWSVIARFFPGRTDNAVKNHWHVIMARRGRERSKLRPRGLGHDGTVAATGMIGNYKDCDKERRLATTTAINFPYQFSHINHFQVLKEFLTGKIGFRNSTTPIQEGAIDQTKRPMEFYNFLQVNTDSKIHELIDNSRKDEEEDVDQNNRIPNENCVPFFDFLSVGNSASQGLC
The following text describes a protein:
Function:
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
Sequence:
MPPAVRVPGGLKFMIQPFTADPIRFVAEDGRPVLALPERYTPALLRELHRLMLQGREFDRKLITLLRQGRTSFYSQASGMEATQIGLAKAIRAGHDWVWGYYRDQVLGMGLGVPMFTLISQCLGSNTDECRGRQMPHHFSSRAHNFVSASSSIASQVPPAAGNARAQKYLGTDEITVVTFGDGATSEGDWHTGMNMAGAMQAPCLFVCENNQWAISTHIRHQTASENIHIKAKAYGMPGFYVDGNDVVAVMEVCHHAAEWVRAGNGPALVECLTYRVGSHSNADADAEKSYRTRDEVNEWLGRDPIQRVENLLEHLGDPISAEERAGMIAEIHKQIDDDVRRAEAAGYPDWRIMFEDVYSDMPDHLRQQAAMLREEQGGSA
The following text describes a protein:
Function:
Acts as a cell-specific local repressor of quiescent center (QC) self-renewal by cell divisions in the primary root. Counteracts brassinosteroid (BR)-mediated cell division in the QC cells. Regulates maternally seed size, especially before the heart stage, promoting both endothelial cells expansion and cell number in the outer integument layer of the seed coat. Modulates the expression of genes involved in cell wall metabolism such as cell division and expansion. Negative regulator of flowering via the repression of FT transcription.
Subcellular Localization:
Nucleus. Cytoplasm, cytosol.
Sequence:
MNPNLLEKDLRGKETTNGSIRYKEANNFRSLPNSHTAACKTSLNNPSISRNHPHNKSASVLESEDEHGNERGENEKSLRMRGKSGINTKVCSRGHWRPTEDAKLKELVAQFGPQNWNLISNHLLGRSGKSCRLRWFNQLDPRINKRAFTEEEEFRLLAAHRAYGNKWALISRLFPGRTDNAVKNHWHVIMARRTRESQRQRQQPPPTLSRDAEMTVSSSCRYNQGKFINEEDDDDDVSAVSTCTTELSLTPPSSAYQPRFFNYDSTLASGKDGQCVQRAEVNGIYGKKMDHQNHHTISVSERKVEMKMRSGYYYFDFLGVGAS
The following text describes a protein:
Function:
May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.
Subcellular Localization:
Cell projection, cilium, photoreceptor outer segment. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.
Sequence:
MLININSILWMCSTLIATHALHKVKVGKSPPLRGSLSGKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIDDTQDTVSLAVDGVVFHYRASTSRYTLNFEAAQKACLDIGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDMMGKAGVRTYGFRSPQETYDVYCYVDHLDGDVFHLTAPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRPDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQTFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPSAYQRTYSMKYFKNSSSAKDNSINTSKHDHRWSRRWQETRR
The following text describes a protein:
Function:
Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling.
Subcellular Localization:
Cell projection, cilium. Cytoplasm.
Sequence:
MASAEDEVLTGLHQLLKNIEPTLKSASGSLDVAEDVLLHLEETDESFHKHDFVKYIRENIETYIGPLVDEEIEKRSISGAPNSVSRQETLVQAVAESAVESRLFSDLTQKICSSTSSAANTLLRSLDEEHNSMGSDEEVESQLSKRMSEGASTCGSSFNQDSLRRCSEQFHCIADEMDCRKPIDIRRDALTRLCHVPPSDVMASESWSQLRVSLMDALADPDPFLSHTTLSFHAKMFAVSNYQIMRETYTCLAEHLIRWFKSSSQSLPSIYEPLDITKSEVVLLIKRIRLLNEFQCEVPSIWVRYPESFLEVIVDSSLSLLCLQLKLGKNSNNSDKLTALHFLSLIDIRANWFRKWLHGNYSRATLINSLEGKYQPVLQDAVLQCLTFCRDSLSKPKSHPHHTPQDGRRTTYTPNEIRYARFVHSLCFVSRLLFYTGGRELFPVSIDIFPHPISVQHLLISWIQLIGLAKSKPKHGHKAYEPASLVCKAICNLCLSNAFVEQCVGDEVISVLLIPIRTWLGKIEPSSKRYSESCMLHIAEILACLTSTCAGRKLLLHGSGSEKKSAAAHVIAEFAQKSLNSKLPSGTLQSAGNIPSYSVVGAFVFVCRQMYNVCEGLLLLLEYNLHQGIAAAWKQAHEKWGDSHAVPLKFDDSNENIDEQSSPTQSSSRNLVLWEETLLDNLLNFAATPKGLLLLQQTGAINECVAYMHSRYTKKLQVSKCEKFGYGVMVTQVAATAAGTSALYKAGFLRAIIHELWSHLEHATDEIRMTAPRPFPLHPIDRSVHKSFMGLVNVLSSYPAVHELFYQQQLPNKTSYTFREMPESPINLIDRLVMINSEAKIHALFNYEQSHVFGLRLLAVLACHLDSWLLLETQYNIQHTLLELQKNNRTIEGYMILNFREIIIDRLSIERNYLLVKTHMIGGEGERLLPSRSLDDNSQQRRQRHYVWPLFYHFPIPKEYTPTIASQTSMKKESALSRFLASSKSSEKNRQWLEQLRSTFCKVMKTAASTVRGGVLIETIEKTIQALERMPEERVFKKTPTRGQFRDSGSASNNNLQNIGVKLAIRYGKQINALKANPETAAANLVTVLRTCSQFLAQQQSYSSVLKLTSGPYPCYDWFVSSIFLMVSGSKDRSLSILMKLSELLCSGYLWPARLHASIHLSEGVRASGIPPVFSCTGHHVELILQAEHPLIYSAFRMSGYTPSQITQHWLTQCFWNYLTWTQVTHYIVTVITMGCDYQVYICVSILKHLQHEILSHRQTQDLQVFLKENPIEGFVVSEWFDYMNKLEQTYRNTVLTSMRNIA