lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Inward rectifier potassium channel that forms the pore of ATP-sensitive potassium channels (KATP), regulating potassium permeability as a function of cytoplasmic ATP and ADP concentrations in many different cells. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. In pancreatic cells, it forms KATP channels with ABCC8/SUR1. Can form cardiac and smooth muscle-type KATP channels with ABCC9.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MATANVAHRTSGSRAASCRNVFTTLVDLKWHHTLLIFTMSFLCSCCSSPWPGGLLAFAHGDLDRHGPVAGAGPGAGGERGLRALRDQHPLLRLGLPLLHRGPGDHRLRRPHGDRGVPAGHPGPHRAEHRGADGQRHHAGLHLHEDRPGPPAGRDPHLQQARGHRRAPRPPLLHAAGGRPAQEHDHQRHHPHAGGPQDHQPRGRVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSSSPSTTWRRATCTTTRTWRWSSSSRAWWRPRASPPRPAPPTWPTRSSGAGASCPSWPRRTGATRSTYSKFGNTVKVPTPACTARQLEENRSLLDTLPLTSPKSQLRKRSVAGARAKPRFSIAPDSS
The following text describes a protein:
Function:
Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1. Regulates cell shape, spreading, and migration.
Subcellular Localization:
Cytoplasm.
Sequence:
MSWLSSSQGVVLTAYHPSGKDQAVGGPGGKGREEATSSRKYGQCTMNQEITKVTEKPPFDRSGSQDSLDELSMEDYWTEVENIKKSSENRQDQEVVVVNEPDEGELEEEWLKEAGLSNLFGESAGDPQESMVFLSTLTRTQAAAVQKRVETVSQTLRKKNKQYQIPDVRDIFAQQRESKEKAPDGTDLQSVRTDENKHQGKDDQASSLVVGEKELTPLVPEEAPASETDINLEVSFAEQAVNQENSKEKPQKSKGNDASLPNFRLPKDKTGTTRIGDLAPQDMKKVCRLALIELTALYDVLGVELKQQKAVKIKTKDSGLFCIPLTVLLEHDQRKVPGTRIPLIFQKLIARIEEGGLETEGLLRIPGAATRIRNLCQELEAKFYEGTFNWESVKQHDAASLLKLFIRELPQPLLSVEYLRAFQAVQDLPTRKQQLQALNLLVILLPDANRDTLKALLEFLQRVIDNREKNKMTTMNVAMVMAPNLFMCHALGLKSNEQREFIMAAGTANIMHLLIKYQQLLWTIPKFIVNQVRKQNTENHKKDKKAMKKLLKKMAYDREKYEKQDKNTNDADVPQGVIRVQAPHLSKVSMAIQLTEELKASDVLARFLSQESGIAQTLKKGEVFLYEIGGNIGERCLDDDAYMKDLFQLNPSAEWVIKSKPS
The following text describes a protein:
Function:
Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e.g. YUC genes), as well as genes affecting stamen development, cell expansion and timing of flowering. Synergistically with other SHI-related proteins, regulates gynoecium, stamen and leaf development in a dose-dependent manner, controlling apical-basal patterning. Promotes style and stigma formation, and influences vascular development during gynoecium development. May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM).
Subcellular Localization:
Nucleus.
Sequence:
MMMIMGRKCEDCGNQAKKDCVYMRCRTCCKSKAFHCQTHIKSTWVPAYRRSHHKHQSQPLSTSIPKGVQIHTTPGHFPAELSSLADFRCVKVSSIDDGKEQYAYQTTVNIGGHVFRGILHDQGLHKVMVDHHYNKNSNNHQELLTPSTSSCPLKITSPFTDFMFGTRFSSVLRR
The following text describes a protein:
Function:
Antimicrobial peptide that may act by disrupting the integrity of the bacterial cell membrane. Has antibacterial activity against Gram-negative bacterium E.coli NBRC 3972 (MIC=10 uM) and against Gram-positive bacteria S.aureus NBRC 13276 (MIC=2.5-5 uM) and B.subtilis NBRC 3009 (MIC=0.5-1 uM). Also shows potent activity against antibiotic-sensitive and -resistant Acinetobacter baumannii (MIC=1.8-3.6 uM). Shows cytolytic activity against human and sheep erythrocytes. Toxic to cricket A.domestica.
Miscellaneous:
MISCELLANEOUS: Fragments comprising residues 10-25, 1-19, 7-25, 1-22, 4-25 and 1-23 have been detected in venom but it is unclear whether they have a physiological role or are simply due to degradation.
Subcellular Localization:
Secreted. Target cell membrane.
Domain:
Amphipathic and cationic peptide with an alpha-helical structure.
Sequence:
MKYRKQLLVLFFAYFLVVNESEAFLGSLFSIGSKLLPGVIKLFQRKKQRALMKRDLQDRMDPYQRNLKLDRYLKQLALD
The following text describes a protein:
Function:
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
Sequence:
MAESSVAFFLAKLSNLVIQEASLFGEVEGQVKLLRNELKWMRLFLKDADSKCIYDERIKLWVEQIREVAHDAEDVIDEFIFNMDNQRQKRLKNLKFLKRLPTCVGFADKLPFIHELDSRVKEINVMIEKIMVNRSKYGLEALVTPSSTSTDHGVSQQERRTPTVEETDVVEIKDGMEVVKQMLIKEDPMQPRAVVSIVGMGGLGKTTLAKKVYNHSDVKQHFDCQAWVYVSQEFKPRELLLSIISSVISLSNEEKKEMREMGEDELGGKLRECLNDKKYLVAMDDVWSIEAWSSLRSYLPESRNGSKVLMTTRNKEIAAQANPHEVVGHTDSQALVYELRIMDGNESWELFLKKTFGARDITPLSLSKALEELGRKIVAKCKGLPLAIVVLGGLLSTKEKTEPSWERVLANIDWHLNRGPESCFGILALSYNDLPYYLKSCFLYCGIFPEASEIKASKLIHLWIAEGFVERRGKEKLEDIAEDYLYELIHRSMVQVARKKANGRVMSCRIHDLLRDLAISEARDAKLFEVHENIDFAFPSSVRRLSIHQHLVKNNISQHLHNSLLRSLIFFADPIERRDWRSIREHVKLLSVLDLGRIKGNYILPKEIGELIHLKFLCIKGTDRVTLPSSIKRLVNLQNLNLGYTDSYIPCTIWKLRELRHLNCRGGEISSQSKLNKCMNGYLGVEQLTNLQTLALRPGSWLEGDGLGKLTQLRTLNLTGWLTPYLEKGFFDSIAELTTLRTLVLKDSMGCKKKEELVIQFGWKWQQHFVEDKTLIPGLMSFSRHTYLYKVGLQGKVDKLPEQTEFYPPNLLELTLCDCKLKDDPMLILEKLPTLRSLTLSCGSYVGKKMVCSFGGFLQLESLELVGLSNLEELTVEEGALCNLRTLKIWTCCRMKKFPHGLLQMKKLEKLDLFKPGDELIEEVQQREGEEWDRIRLITSIKK
The following text describes a protein:
Function:
Transcription activator. May act as tumor suppressor.
Subcellular Localization:
Nucleus.
Sequence:
MNTKDTTEVAENSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMEPVSWQCLYGCYVHSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHGIKWSCGNGLEEFSVEQLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLASISHSKPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLASQAEPRPPVSLAVVVGSEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVNPDFPEAEGTHTPCPALEPAAALEPQAAARGLPPQSGASGRRGNKFFIQDDDSGEELKGPGTVPPVPSPPPSSPSSPAALQPSGRATRGETLFGGSAGSTSELEPFSLSSFPDLMGELITDEAPGVPAPSPQLSPVLNTITDFSPEWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDSQFRMSILERLEQMEKRMAEIAAAGQAPGQGPEAPPIQDEGQGPGFEARVVVLVESMIPRSTWRGPERLMHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEADPLNVDHFSCTPLMWACALGHLEAAVLLFCWNRQALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQELSVEHPLALSPQSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPMLASEISMETIPGQLSFGAPETPLLLMDYEATNSKESAPSPSGLPLAQDDRAAPEDADSPPAVDVIPVDMISLAKQIIEATPERIKREDFSELPEAGASPREHTGTVGLSETMSWLASYLENVDHFPSSAFPSELPFERGRPAIPPAPSWAEFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRPSGPLPSRNKGTFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGLAT
The following text describes a protein:
Function:
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Subcellular Localization:
Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton.
Sequence:
MRAPVYVRRDSDSSLPIRRDSRDEGEEDLEHTGLRKKKLCLLITVLILLALFSFILLALNIMIIRTLEMSHQGMRLIKFYKVKNPTTGEQEKMVHFGGREMDLYRVVASSGKVHGTVDTDLNVYGSRVVIQGQPDGSRLILQEEGCVLDGLDDFQIISSKYSRPVFSARHPLLPLDKKIKRISSSTIITNKIRSAVNERLRVGVEDISIRGNEAVLFNGRAIHMASGNAVNFNTTKDGILHLRGSVFIGGSHSGLPLSQSPSLSASIEAFRLCVCSSPRPILFTVPGNKPCVAPQNICA
The following text describes a protein:
Function:
TQO plays a role in sulfur oxidation and is proposed to couple sulfur oxidation to dioxygen reduction; caldariellaquinone or sulfolobus quinone seem to serve to transfer electrons to the electron transport chain terminal oxidase formed by DoxBCE.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSGKQSEEFKRTEKMTRMEYLFPVRFAVGWMFLDGGLRKAVLKPAKLDPNSASFVGGKLVNFLPHAGPFKGLLLMTLENRSLDVTFLTVFSYIEIIAGLFIIIGLLTRLAALGALAMSVGFAPAYWLGSTCEDEWQIGALLTAGSVTLMLTAAGRVWGLDYFLYKKLGDRPIANVPILKWIKLW
The following text describes a protein:
Function:
Growth factor that supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Involved in the development of the neural crest. Might control the size of non-neuronal cell population such as haemopoietic cells. Acts by binding to its coreceptor, GFRA2, leading to autophosphorylation and activation of the RET receptor. Heparan sulfate-binding is required for signaling.
Subcellular Localization:
Secreted.
Sequence:
MQRWKAAALASVLCSSVLSIWMCRDGLLLSHRLGPALAPLRRPPRTLDARIARLAQYRALLQGAPDAVELRQLTPWAGGAAGPRRRAGPRRRRARTGSRPCGLRELEVRVSELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRVRRERVRAQPCCRPTAYEDEVSFLDAHSRYHTVHELSARECACV
The following text describes a protein:
Function:
Member of two distinct condensin I complexes, the condensin I complex and the condensin I-like dosage compensation complex. The condensin I complex is required for conversion of interphase chromatin into mitotic-like condensed chromosomes and for chromosome segregation in meiosis and mitosis. As a member of the condensin I complex, further controls crossover number and distribution in meiosis by restricting double strand break formation, probably by influencing higher-order chromosome structure. Regulatory subunit of the condensin I-like dosage compensation complex that associates specifically with hermaphrodite X chromosomes to reduce their gene transcription during interphase, possibly through chromatin reorganization.
Subcellular Localization:
Chromosome. Note=During meiosis and mitosis, localizes to condensed chromosomes in both sexes. Localizes to the spindle midzone in between separating chromosomes during anaphase and to the midbody during cytokinesis. During interphase, localizes specifically to X chromosomes in hermaphrodites after the onset of dosage compensation.
Sequence:
MPPKKRIRGPKLPALREEKSTGTDVASDESFNESADFLNNEELNNDQNDAENTVLSEGVSTLRINENMTKEDRACISAALFIKKRVVESIRTVFQSRDDINDEIHTSSRKLIAAFKKADQNRKKKVDLMKVFLDEIDVRLSMIIEEVTVPEHRARVFKLIAVTITEIQAFKLPSDLLDFIINFINTWGHSDNVAARINTTCFISYIFETGKRYLTTEGEYSGFEVKIAAKMFLQLKRALLDKEQTARVPAIRGLGFLQEIPIPSNWPVDAMKHSPRELLLRSCRDTAWECRLVAVQSMVPLETDVRLLSDIVYYDKCLNVRVAALEQFSNLRPNKHVREKIEMLDLCLKDHEVNIRDAAKEVLKNWVRNLSTRWSESQKSKDSNDVVILNSNSESTTGEENKMKGYILAAQALTLLWLTGALETLEGHSNLRRLITHTLDVIRQMYVCQADPINTFAEVLISDLREKMKSSAVPIITKSTVGSILDDSELADTQDPSTNRAMIFFWRCLVDYISDRKRNDADKINAMSRFVSPLRTMVEHVEKILVRVKNLDVYPNISQRADYEDHTFVLQMSIVENIICVMRHAPTDQPGVDAYKQMLISMLMNVFYQKKVIDLIVQELAQFYKEDPNALFTLFNDRIEEMRSKYKSGQFPVIENSVPVGETKVRKDLEEETRKTGRRTISDKDGIAVIDLYELKVLNALLKTGILLGWSTTYQNRYNNKLREGISSKDLSTRVLCTECIGIGAIYDYDQAENTLREMMKSFNTQDEPVQCSLIAALTDIQIEHGDQVDALFSWNSKQPNFAVFLSDIVVNAHVSGECETMLRAVEAISRLFLNTKIDPNQQKWQRTMVTLMTRASYAITNRFSAKVRSTIIVMLKFFCSINKNNQLLLIKSFHNFFDMWANSTTPERLTENRHEMVTKLKRCAATFVALTRHSTLPLEEQKKCKPTHVDLVDDIFHEMAGAPDSTSVDYYICALNFVEYQSLSRSALTKIHGDLESYIFLHELDGDKHRYNELRKAHRKIAKILGLNEDEIEEVPSKTDLRKEAAPSKTNKRNANLISTDIAVDNDVNMEEDDKPGPSRPATVRKPRAPRATPASATKKKPLVEEDALEILKSPPRNTKKPPSRPTTATRPTAVAARTAPPRSARKLRSEK
The following text describes a protein:
Function:
Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Required for correct chromosome segregation where it has a role in the formation and/or maintenance of specialized chromatin at the centromere.
Subcellular Localization:
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore.
Sequence:
MSSHGDASVLPKIALESINDYSYVKSVFRQAIQEKLAIHLPEQASREAGMGREDQLRIRVKEMLNELIESTFSIIQENVTINGFDANSALQDPKNSDQIEPFDLALRTRVQQLFNEVEDAHVLVARYRKSVPAQYEKAYVDAMEQQTAFLRNVKDDYVSLQDKEVENPDEQTSTTVFRKEDIDRYEQTIAKVAYLKKNLPRVVARLEKTP
The following text describes a protein:
Function:
Cadherins are calcium-dependent cell adhesion proteins.
Subcellular Localization:
Cell junction, adherens junction. Cell membrane; Single-pass type I membrane protein. Cytoplasm. Endosome. Golgi apparatus, trans-Golgi network.
Sequence:
MYYFPVFIIVITVESHLSKPLDYPSHFCSQYFQYIVIFWCQIHKYGNYNITLLCIELLFLSNLLYNMMSFPLTLALSLPVTFTDCTDRTQVPFLSDDTRLRLRPDGTLVVKRPLRLQSHHHSFSVHGWDAAGKKHSAQVTLRLRHGHRHHEQHSQRHPPHMLGHGEVLTFPQSGPGLRRQKRDWVIPPIYCSENEKGQFPKQLVQIKSNKDKDTKVFYSITGKGADSPPVGVFSIIRDDGWLMVNHPLDRELIDRYVLFSYAVSANGQSVEDPMEIIIKVGDQNDNRPEFTEKVFQGFVAEGATPGTAVMTVTATDKDDSVDTYNGVVTYSITNQNPKEPHSQMFTINNQTGLISVITTGLDRERYPQYELTIQATDMLGQGYSTPGTAIITVTDKNDNPPIFDPKTYVASVPENVANYTVAQLTIIDADQENTPAWKAKYTISAGNGAGNFAIETAPDGNDGLLTTVKGLDFEFQQKYILEVTVVNEEPFSVTLPISTATVTVNVQDVNEVVATVSAKDPDTFLQQTVRYSIGSDPAGWLRINAENGIIESRSELDRESPFVQNSTYVALVLASDSGSPPATGTGTLLVYLQDINDNGPEPDPRAFDICSRSPEPQVLGIVDKDLPPNTDPYSAMLELGSSANWSARVNNDRLTLQLTKVLDPGDYNVAVKLTDGQGLSHLTMVKARVCDCEGAAQNCERRGAIGSAGMGVPAILGILGAILGFLILLLLLLLFVRRRKVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDYDLSQLHRGLDARPEITRNDVAPTLMPAPQYRPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGNGSEAASLSSLNSSGGDQDQDYDYLNDWGNRFRKLADMYGGGEEEEDN
The following text describes a protein:
Function:
A flexible structure which links the flagellar filament to the drive apparatus in the basal body.
Subcellular Localization:
Bacterial flagellum basal body.
Sequence:
MSVTSALYTGISGLNANGEAMSVIGNNISNVNTIGFKQGRMLFSDVLSSTISGGSQIGRGVQIQTVENQFTQGSFESTESGTDLAIQGDSFFVVQNTSGRYYTRAGAFSFNKDKTLVNPEGYQVMGYGIIPSSGLSDGVLKPIDLTNFATTPPKQTSTVKFVVNLDSTQTTPTLAWDPANPVATSNYSTSLSVYDSQGNAHTATVYFRKTADNAWDWHVILPDAAAGTPGSTTTPIDGTLTFDATGALTAQTPLAGAAQNITFAGGVTAPQPIFFDLGVGATTQYASSSVVSSQTQDGYYQGTLTKVTIDDKGYVNGVYSNGQLQKLYQVALAKFSSTAGLSKAGGTLFEETLESGQPLFSDASTPGVGKILANSLEQSNVDMAAQFVKMITTQRGYSANSKTITTADEMLQEVLSLKR
The following text describes a protein:
Function:
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
Subcellular Localization:
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Domain:
Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
Sequence:
MLDKLGENLNKALNKLKAAAFVDKKLIKEVIKDIQRALIQADVNVKLVLKMSKEIERRALEEKTPKGLSKKEHIIKIVYEELVKLLGEEAKKLELNPKKQNVILLVGIQGSGKTTTAAKLARYIQKRGLKPALIAADTYRPAAYEQLKQLAEKIHVPIYGDETRTKSPVDIVKEGMEKFKKADVLIIDTAGRHKEEKGLLEEMKQIKEITNPDEIILVIDGTIGQQAGIQAKAFKEAVGEIGSIIVTKLDGSAKGGGALSAVAETKAPIKFIGIGEGIDDLEPFDPKKFISRLLGMGDLESLLEKAEDMVDEKTEESIDAIMRGKFTLNELMTQLEAIENMGSMKKILSMIPGFGGAMPKELSHLTEAKIKKYKVIISSMTKEERENPKIIKASRIRRIARGSGTTENDVREVLRYYETTKNAIDKLRKGKMLRIGGPLGQIMRQLMFKEG
The following text describes a protein:
Function:
Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit polr2a, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs).
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MITSNNNNKNNNKKDVEMKSNEEEGDEIFFSILSGDTNNLFKFLNNNNSNNNNNNNNNNINNSIDIYLPYIIVGILEKNKDLLDEDENLKKLFYSPIYSKSIHNINQYQSLNFDHINEFIKDQVRIRKKLNHVNQDKKDTYLDNIDNPKYQFENGDKEVKMKLVLSDIIALLEFSEMQQSLTISKETKYDAPFIDTPIYNNELNLIFPIICYKCLKHIDFNKLTLSILFLNQANYLIKLLLSNNPNEFNEIIEIVISSIGLIGVEKVKRVLLEICKLSKYCSRFIRTELINRQMLPDLVLLITSQFVKDEIDLLSNIISNRIENQWLKEYISQKDQFSTFNEIRDSLFSTLELISKEISSNSNNNSNNLEHSFIVKSIIRLYCGFSGLLGIKMNQQEISISLSFIEKSIFKNYSKIFLCFLLVCEGLVKTIHPKKELVGYLNHLCKVGNCDELLLLISIYFHTHQLQNIALLVKNILGFRPSIHTESLNQIGEILTKEIYTESLVAKRAQQLPIIEKLNTNHQNISIVCVYHLLSERIFEKYETDVGNWCWSQLTKSSTPIHYLLPSLLDQLCKNIIEPSINNNNTSSTTSIINTSTTAAAASTTASNANTTAATTTTTTAATITTATTTGTTTGISPSSSTTTTSSTGGATSTSISSPNSTSLGNSYLFSTFSSTSSSSSSGLPFYMKRISESIIMNSIQQSQSNLSVQILIIYFVLRYNDSVIKFKSEQKGKPIQFLIETTQLREYNIEFLSKLPIQNCINVILSNQSDYFYIIPPFLYLILSQFPQFFNINLLLLEEERLLNPIEKFIYLPNFYSINGGANNNSGGITNEFLKDTLKRTLSQPTSVQLILRYLNTLSVKELLPFTTTLLDNLLPIIIKNRSLPSVSALISPFVEIWERVFPISQSSIALKTINILTCINDDKSTNNNKDLEDYNNNNNNNNDDVKMKDKEKEDKEEEEEEEILLPISNYTYTDIISDPLVIFRSHPTVFTCPPLFKILLQILFFYMVSSKKNLQNQLHTSSGSGSGTTSNVTLNKQQQEDVSTLILTQESTIIQILLEICLIDGIDTKGLNKILRNKNKKFKESYDPVDIEEIRCQICSFIHQMFIDKPLIIKLVHFQGYLSQLLPITVTLIPSMHICFEFIPELLAQPSLEKQIFAIQLLSYLSEKFPIPKSLKICRQSQTRISFNLNSNTLSYDDRIKFLHSILPSITRITKTFPLLAEDFVSILMEQLPNKHNYQQNLKSFISSIDFNLNSNLNNYTNSIYLQNNKNNNNSSNNNNSNNQNDLLNIDIDNNINSNNNNNLRNINFKKVSNDDKSFFSKVSKNESWLSIKENNDPFNIPIEQEIHQAIQIIIKNLSK
The following text describes a protein:
Function:
Putative Notch ligand involved in the mediation of Notch signaling.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MRNLFVFFSLSSLFLLSNAMFIDPGKSGALELVLKVESSQTTQIAVNSNVTSIDLHTNSTHYIEYREMDFRGIISIRLQTKFMKSRYGSRNWHMVVFDPLQGIINVDQLPRPFDGMVVKVKCERNWFGEYCDKYCDEDAAHLVGMRCNKKGVMGCNEGFCGPNCDQTKSQCSMMCACENDAPCYSSTDPRTSREYVYCECLTGFEGKYCQNVTFPPEMPKFRTVMLGANGKIFKVLENKNLVKNEFYWANSSAKFELLAENAENFPAPESFWQLAREFLEDLFSETDPWTPVIFIGIFGLFLVFHCQAVDVESSKKLIVFDV
The following text describes a protein:
Function:
Could play pivotal roles in cell cycle and DNA regulation. Involved in innate immune defense against viruse by positively regulating the viral dsRNA receptors RIGI and IFIH1 signaling pathways. Involves in NOD2- and NOD1-mediated responses to bacteria suggesting a role in innate antibacterial immune pathways too. Could play a central role for the formation and/or maintenance of the blood vessels of the circulation system.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Detected around the nucleolus.
Sequence:
MEKATVPAAAEGEGSPPAAAAVAAPPAAAAAEVGGGARPASSPRGMVRVCDLLLKKKPPQQQQQQQPPHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGTSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLAAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANLAATLPVRSKAASKQKSNSHLPANSQDVQGYITNQSPESIVEEAQGKLTELEQRIKEAIEKNAQLQSLELAHADQLTKEKIEELNKTREEQIQKKQKILEELQKVERELQLKTQQQLKKQYLEVKAQRIQLQQQQQQSCQHLGLFTSVGVGEQLSEGDYARLQQVDPVLLKDEPQQTAAQMGFAPIQPLAMPQALPLATGPLPPGSIANLTELQGVIVGQPVLGQAQLAGLGQGILTETQQGLMVASPAQTLNDTLDDIMAAVSGRASAMSNTPTHSIAASVSQPQTPTPSPIISPSAMLPIYPAIDIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGKGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQATADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFPSDSECMRYIATITDKEMLKKCHLCMESIVQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEEEPEVLTEPPSATTTTTIGISATWTTLAGSHGKRNNTITTTSSKRKNRKNKITPENVQIIFDDPLPISYSQPEKVNGESKSSSTSESGDSDNMRISSCSDESSNSNSSRKSNNHASAVVTTTMASKKQPSVLVTFPKEERKSVSGKASIKLSETVNEGTSNSLSTCTKSGPSPLSSPNGKLTVASPKRGPKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNINAIRECTGAHIDIDKQKDKTGDRIITIRGGTESTRQATQLINALIKDPDKEIDELIPKNRLKSSTANSKIGSSAPTTTAANSSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHFGGTFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTASSSASAVPGTTSNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNSTAPTNATYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKGASASEQEASSPPVVEPANSRPPHSSSSSGSSSGHSTQQQPPGSVPQEPRPPLQQSQVPSPDVRMTVPPTATSSAPVAVPSTAPVTYPMPQTQMGCSQPPKMEAPAIRPPSHATAAPHKTPAPVQSSSASVLNVNHIKRPHSVPSSVQLPSTLSTQSACQNSVHPANKPVAPNFSAPLPFGPFSTLFENNPTNAHAFWGGPVVSSQSTPESMLSGKSSYLPNSDPLHQSDTSKAPGFRPPLQRPAPSPSGIVNMDTPYGSVTPSSTHLGNFASSLSGGQMYGPGAPLGGAPLGGAPTAANFNRQHFSPLSLLTPCSSASNESPAQSVSSGVRAPSPAPSSVPLGSEKPSSVSQDRKVPVPIGTERSARIRQTGTSAPSVIGSNLSTSVGHSGIWSFEGIGGNQDKVDWCNPGMGNPMIHRPMSDPGVFSQHQAMERDSTGIVTPSGTFHQHVPAGYMDFPKVGSMPFSVYGNAMLPPVAPIADGAGGPIFNGPHSAEPSWNSLIKMVSSSTENNGPQTVWTGPWAPHMNSVHMNQLG
The following text describes a protein:
Function:
Has antibacterial activity.
Subcellular Localization:
Secreted.
Sequence:
MKIHVFLFVLFFFLVPIATRVKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANCYM
The following text describes a protein:
Function:
Stress-induced membrane protein that can bind heme and may play a role in the transport of tetrapyrrole intermediates during salt stress and contribute to the detoxification of highly reactive porphyrins in the cytoplasm.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing TSPO show increased sensitivity to ABA and salt stress. Cultured cells overexpressing TSPO have reduced greening and chlorophyll a content under light-growing conditions.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Plastid, chloroplast membrane; Multi-pass membrane protein. Note=Localizes in chloroplast upon salt stress.
Sequence:
MDSQDIRYRGGDDRDAATTAMAETERKSADDNKGKRDQKRAMAKRGLKSLTVAVAAPVLVTLFATYFLGTSDGYGNRAKSSSWIPPLWLLHTTCLASSGLMGLAAWLVWVDGGFHKKPNALYLYLAQFLLCLVWDPVTFRVGSGVAGLAVWLGQSAALFGCYKAFNEISPVAGNLVKPCLAWAAFVAAVNVKLAVA
The following text describes a protein:
Function:
Helicase with 3'-5' helicase activity involved in genome stability. Functions in the nucleotide excision repair (NER) pathway and plays a critical role in DNA interstrand cross-link repair. Unwinds relatively long duplex DNA up to 120-bp and requires a long 3'-tail of at least 70 nucleotides for efficient unwinding of duplex DNA (By similarity). Shows both processive helicase and DNA strand annealing activities (By similarity). Affects telomere length by a non-catalytic mechanism, probably through inhibiting telomerase by competing with it for ssDNA binding (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSQTPIKKEESNDQDDKFEFKKYINEGKLPLKADNPKKKPQLGTIQANQPIPSIFDNLFNLFKVINTTYTFLYLRNSLTITFPLLNSSVKQSLKKELTIGDLSQLREICPQIIELNYKSLASLALEINKNVYTDLNPELYTGSTVSQSSEYVLVIELLETQERSSKRRRREGPTMKANIQRQKLDFNNLKKAIELRNQKFLQGIKEYIKKCQLTELDPTQQLLTQSRKNQPVPPDSPSIPNDSIENCNLNTKACSIEELLNEIASESSYEGQIVQEALHTYPAVEAQYGALSRPLSQELINALYTSRNIEKTYKHQADAINHLWNGFHVIVSTSTSSGKSLIYQIPILQSLLEDNQSTAFFVFPTKSLAQDQKKSLIDILSYMPTLKNIRVDTFDGDTPLESRESIIRSANIIFTNPDMLHQTILPNANRWYYFFKNLKLFVLDEAHVYNGIFGVHVAFVLRRMRRIAEYFGNSQYRFVSCSATIEDPLQHMKKIFGVDNIKLINYTSSPSGSKKFVMWNPPYVDPKHPDDGKKSAISEASKLLIKFAEKRVRTIVFCRVRKTCESLMRLVRQELKTKQKGDLLSKIQSYRAGYTVQERRKIESEMFNGKLYGIIATNALELGIDIGSLDAVITIGFPYSLSNLRQQFGRAGRRNKSSLAVYIVETFPVDQFYLKHPILIHTQPNAELTLDLTNEVLLASHLQCAAYELPINIRSDEKFFGNQIQDICEANLEMVEESYRPHPKYLPFPASQVRIRSVSEDMFTLVDVTNDKNVILELLEPFRVALTAYEGAVYVYQGKTFIIRLLNINKRIITAHQVDVEWSTLQRDFTDVDPVRSLMKKTMHGSTNIYFGAVKATLHVFGYFKVNKQKDILDVVDITDHPVEIDSRGFWIDVPWHIIEVLSLKKINGAASIHAAQHALLSLMPIFISNSGNDIRTECKAGEKEYKEAKSERRRPSRLIFYDNCGDSSGAGLCNKAYEHTDELITMAIERIESCDCKVREGCPGCITSSKFEGGVCSGEVLDKVGALILLKMLLCQHVNLDIYADGPEIDSYHALRTLIPSC