lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
Sequence:
MKEIDELTIKEYGVDSRILMERAGISVVLAMEEELGNLSDYRFLVLCGGGNNGGDGFVVARNLLGVVKDVLVVFLGKKKTPDCEYNYGLYKKFGGKVVEQFEPSILNEFDVVVDAIFGTGLRGEITGEYAEIINLVNKSGKVVVSVDVPSGIDSNTGKVLRTAVKADLTVTFGVPKIGHILFPGRDLTGKLKVANIGHPVHLINSINRYVITREMVRSLLPERPRDSHKGTYGKVLIIAGSRLYSGAPVLSGMGSLKVGTGLVKLAVPFPQNLIATSRFPELISVPIDTEKGFFSLQNLQECLELSKDVDVVAIGPGLGNNEHVREFVNEFLKTLEKPAVIDADAINVLDTSVLKERKSPAVLTPHPGEMARLVKKTVGDVKYNYELAEEFAKENDCVLVLKSATTIVTDGEKTLFNITGNTGLSKGGSGDVLTGMIAGFIAQGLSPLEASTVSVYLHGFAAELFEQDERGLTASELLRLIPEAIRRLKE
The following text describes a protein:
Function:
Is required for spatial control cell division during leaf development. Through an association with microtubules, acts both for the positioning of cytoskeletal arrays that establish planes of cell division during prophase and for spatial guidance of expanding phragmoplasts toward preestablished cortical division sites (CDS) during cytokinesis.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Note=Preferentially localized to the preprophase band (PPB) during mitotic division.
Sequence:
MVARSPNAKPDRQKAAALAAAAALNPALLRETLKKVDRCMARLQELQYTVAGGAKVVSGVSLSPRSTRGYLRTSLRCKQETVRMRGGASAQKRSPSGKFGGGVGGEGAQWRRMSLPAMLLGETVLEIVQASQFARDIVTAAGATNREPPRTPKPAPRTRKPAAGEPTPLRARRAREKQSHRGGAATRGADAATPPSRSRVRSRIQFKPVSPVAVGRPSVSANRVSPKNRPWAKKAVMFPNPTFHASTSAATDPCATPSPSKKQKRLYKTRSPVAARQTPHKFLVKSPPSALGSKLRMHGKALPARPAAVSPPPPVKAQASPAKTRRCSFSPSRLATRLMSPIKARLSLGRSRDSGVGVGGGPMSGLKQRPGVSLTVRTVSSKISSR
The following text describes a protein:
Function:
Catalytic component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Has a role in regulating heterochromatin propagation and euchromatic transcription. Also has a gene activating role.
Subcellular Localization:
Nucleus.
Sequence:
MMDLSSKDALSDVLKDTHAQSSDPSLWAIFGHQSSDNVHEGGNESVSVEQEIFDLSQLSERPVSETVSKASIPTNINGLSQVKPSALEKSQEVLSLQKLPIKGRRPAGRRGRPALNTSNSLERNGTRYVSAEAPISVKSSIPAIPRVTFERLCYESAIASNLPPNALSPLEAEMLSEILENPTWLSLYLSIRNGICYLWHRNPTLYVSFNEALGIVREKKAFPLASLAFEFLSRNGHINYGCIYIISSLKLDESLSQKTVAIIGAGMAGISCARQLTNLFAQYEQDFLSRGEKPPRIVIYEASERLGGHIYTHMVPLSDNEVSEKSSLATTVNATNECMVNLLTDSLIGMPTLDSDPLYIISSQQLSLDAVHTRNREFILHDIENGRIDTEHVQRIFRLFDALLFYFNASASKQPLHSLITPPEQEFIQKLDQIGWYISIEAFPLQIKDTLSEFLGNSANTLTSLLHLTVLDLKIFEWFKEYLSQSLSVSLENVYPGSIPNLNLLLGENVASYSFKHGMADMLNSLASTPSPLPILFDQCVHTVKLEDNTVNLSFVNETTVSVDKVVICIPMDKLNTHLITFEPPLEEKKLKAIDRCHFTNVKKVILIFKTQFWEPNISIFGSLPQDSGRNFIFNDCTRFYEHPTLSVFVKVEGIDFMKDDDIVNGIVSQLKKVYKPKSEAINPIRTIISNWENNSYTNHSSYQISNLFLEEDYAILSEPIDNTVFFASEAISQKNSGSIRGAFDSGILAARDVLASLIGNVVLPNTLVIEENLEQPRKTYGTKRNAQQALGKEGERENKEKRISYHTEYLRLRQKRLDKEQQECDLLIAELLGPSPVPPSRPSANPYLLYQKTQWHVCKTLADQDKQRVTGDPEARATKNEIRAKLGKTWRALDSLGKQPWVDEINARRANYSTRLEEYQRQINSYNVRVAQIKSEHQRRCESQPIPEDEAKLKLLAEQEDEHLHPEKEGMSVENSDDDYHDDLDYEDSISEVFPDNFS
The following text describes a protein:
Function:
GTPase component of the Dom34-Hbs1 complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. The Dom34-Hbs1 complex recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel (By similarity). Following ribosome-binding, the Pelota-HBS1L complex promotes the disassembly of stalled ribosomes, followed by degradation of damaged mRNAs as part of the NGD pathway (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MSRHRDVKNLDLDDYELDEEPGEEELTEEQEEEFRSAVATVRETLLGVPISEKEIADTVWYYYFDVEKSVNYLLQKASSKAGAKEKQNTDSQKEKKQNKSKEALADAKDPLDESSNGIKNLSLNKNDEPAFQTNGEVKMKNSSESDNQPEKKKIKKQNPTDLVSVPEIFEQSNPKPVVHLVVTGHVDSGKSTMLGRIMFELGEINSRSMQKLHNEAANSGKGSFSYAWLLDTTEEERARGVTMDVASTTFESDKKIYEIGDAPGHRDFISGMIAGASSADFAVLVVDSSQNNFERGFLENGQTREHAYLLRALGISEIVVSVNKLDLMSWSEDRFQEIKNIVSDFLIKMVGFKTSNVHFVPISAISGTNLIQKDSSDLYKWYKGPTLLSALDQLVPPEKPYRKPLRLSIDDVYRSPRSVTVTGRVEAGNVQVNQVLYDVSSQEDAYVKNVIRNSDPSSTWAVAGDTVTLQLADIEVNQLRPGDILSNYENPVRRVRSFVAEIQTFDIHGPILSGSTLVLHLGRTVTSVSLKIVTVNNKRSRHIASRKRALVRISFLDGLFPLCLAEECPALGRFILRRSGDTVAAGIVKELC
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
Subcellular Localization:
Nucleus.
Sequence:
MDDGGRRESRRHRMDCSKGGHAPWNVVPPYQMKDQEAFIMNTKIRMLCAERDAAVEERDRAVIEKNTVLAERDLAIQQRDTAIAERDTAIKERDNAIAALLFQESTMNGTLGCRTRGTKRPNQSKNHCDNSTDSICINRDVPLTDAFPISAISSEVAKALQVKRTKGNKGMSRKTKKVNEDLNRHLTTDGSKAEWDAQDLGSINQIKFDESSMPIPVCTCTGIPRQCYKWGSGGWQSSCCTTYLSEYPLPQLPNKRHARIGGRKMSGSVFSRLLTRLAAVGHDLSLPIDLKTYWAKHGTNRYITIK
The following text describes a protein:
Function:
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Miscellaneous:
MISCELLANEOUS: [Isoform Beta]: The alternative initiation site Met-94 is uncertain.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKMRVYEYAKALNVSSKEILTALKNMDLEVNNHMAMLEEKAIKKLDAKYKKGGARAKSQKPAETNKNKQPQGVNQQSAGNQPNKIRDGKKNDVQNNQFNKNKKNNNNKKNKRNNNNNKNQHQQKPVKPKKELPEKITFSGTLTVGALAEELGKEPSELIKKLMLLGVMATINQELDKDTIELIASEYGVETEEVIVLEETELEKYEEPDNEEDLEIRPPVVTIMGHVDHGKTTLLDSIRKTKVVEGEAGGITQHIGAYQIEENGKKITFLDTPGHAAFTTMRARGAEVTDITILVVAADDGVMPQTVEAINHAKAAEVPIIVAVNKIDKESANPDRVMQELTEYGLVPEAWGGETIFVPLSALTGKGIDELVEMILLVSEVEELKANPNRQAKGTVIEAELDKGRGSVATLLVQTGTLHVGDPIVVGNTFGRVRAMVNDIGRRVKTAGPSTPVEITGLNDVPQAGDQFLVFKDEKTARSVGEARASKQLEEQRSDKAKLSLDDLFEQIKQGDVKDINLIVKADVQGSAEALTAALQKIEVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDGNAKSTAEAENVDIRLHRIIYKVIDEIEAAMKGMLDPEYEEKVIGQVEVRQTFKVSKIGTIAGGYVTEGTITRDSGLRLIRDGVVIFEGEVDVLKRFKDDVKEVSQGYECGITIKKYNDIREGDILEAFVMQEIERT
The following text describes a protein:
Function:
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
Subcellular Localization:
Cytoplasm.
Domain:
2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
Sequence:
MLGHAAKLLARARFAIAFTGAGISAESGIPTFRGRNGLWKTYRAEELATPEAFKRDPHLVWEFYKWRMRKILKAEPNPAHKALAELENMGVLKAVITQNVDDLHREAGSRKVVELHGNIFRVRCVSCSYRENLKESGRVFEFVREKELPKCPKCGSLLRPDVVWFGEPLPREALEEAFSLAERADVVLVVGTSGVVYPAAYVPYIVKERGGKVIEVNVERSGITPIADVFIRGKAGEVMPELLRRVKDIMAERNHYG
The following text describes a protein:
Function:
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages; This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
Subcellular Localization:
Secreted.
Sequence:
MSSLSILHLLLLLLSLHAPQAQGLPLRTPRTPYSSLMEEIMDDLKKITPSPEGSLNSDEKNILANKSLLQANLKAFMTFATDTFGSDSKIMKNLKEFQPVLPTATPTEDSILIEDSNLGDFRMKLEEYLATIRGYLRHDLAAAETI
The following text describes a protein:
Function:
Part of the distal tail tip complex which plays a role in DNA injection during entry, and in tail assembly initiation during exit. The tail tip complex is assembled successively with three tail central fiber proteins J, one tail tip protein I, one tail tip protein L and one tail tip protein K. The tail tip complex interacts with tail measure protein to initiate tail tube assembly. The formation of the tail tip complex is completed by the addition of tail tip protein M, which is followed by tail tube polymerization.
Subcellular Localization:
Virion. Host cytoplasm.
Domain:
The C-terminus coordinates an iron-sulfur cluster.
Sequence:
MSLNADYQKLEPGNEVRLFSVDGTAFGMSDVLRFHAHNIAHTPEEIEAAGGDENKLPAKSIWWQGEEYKAWPCQVEGIEATTDGTSPQPKLTVANLDSSISALCLAYDDLLQAKVTIHDTLAKYLDARNFPQGNPTADPSQEKLKVFYIDARNTETDEVVEFILSSPMDLQGRMIPTRQLHSLCSWCIRNKYRTGDGCDYAGTRYFDKHNNPVDDPSLDECNGTLTACKLRHGDSNELPFGGFPGTSLIRS
The following text describes a protein:
Function:
Involved in pre-mRNA splicing and cell cycle control.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MRVIVKGGVWRNTEDEILKAAISKYGKNQWARISSLLVRKTPKQCKARWYEWLDPSIKKVEWSKTEDEKLLHLAKLMPTQWRTIAPIVGRTATQCLERYQKLLDDAEARDNEELGLGAGEDESSKPATDARGLRPGEIDTDPETRPARPDPIDMDDDEKEMLSEARARLANTQGKKAKRKARERQLEEARRLAFLQKKRELKAAGINLRAKPKKKGMDYNADIPFEKQPAPGFYDVTEEQAKVHAAPVGSTLRALEGKRKQELDEIEERKKRQKKGDGKSNQTQQFVAAREAQIKKLKEQEQIIRRRKLNLPIPQVGERELEDIVKIGQAGELARELVGDGNKATEGLLGEYEALGQAKMARTPRTAPQQDNVMAEARNLRNMMAAQTPLLGEENTPLHGPSVGTGFEGATPRHDVAATPNPLATSARGGVLTSTRTVPGVGTTPLRTPFRDDLNINDDASVYGETPMNDRRRLAESRRALKAGFAALPKPENNFELAETEEDEEEAEEAEPLTEEDAAERDARLKAAREEEERRELERRSTVIKKGLPRPVNVNTYKLLDDLNSAIVEQTDEEMAAAFKLVNLEVAMLMKHDSIAHPLPGTSTPGGLASEYDMPEDDFVAEAKNAIHTELANALGLPGASDEHLRLAIGAAAEENEAAFAEAWAEEREGLVYSPSTRTWVDKTSLSPEELSACYAAMINASRDRVIAEATKAAKAEKKLGKQLGGYQTLNEKAKKAIVDVMEEIHQTKRDMETFLMLKGIEEAAAPARLEKIREEVAVLKKRERDLQARYAELNDRRRENLAAIEQLEEDKIVLAAQVALEAQEGEVADGDVDMNGA
The following text describes a protein:
Function:
Co-chaperone required during oogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with Hsp83/HSP90 and is required for the biogenesis of all three piRNA major populations.
Subcellular Localization:
Cytoplasm. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Note=Localizes to the cytoplasm but is enriched in the perinuclear meiotic nuage (also known as germline granule or P granule), a germline-specific membraneless ribonucleoprotein biocondensate involved in post-transcriptional regulation of transposons and mRNAs. Also enriched in Yb bodies.
Sequence:
MEENFEPYTPQLLKNPLSYSDLVKKGVEFEVDNSQQNHARDLGLDSDSDSDYEDALDVDGEELRSPWTYSFDELRALMSEIDENIYKRITRTGHVDREAVPNKARVSVRYSGYWEGETAPFDSSLLRGSKFVFETGQGTVVEGLEVAVRSMRPYEQAEFIISYKLLFGELGCPPRIKPKADALFKVEVIDYSLIGDAKGIDAIPQEDRDKFCVVYPKAVDLHLHGKDSVKLGRYQSAATAFERAVSSLNYCRMANDEEERKQTELLTTLNQNLMIVYNKMNKPKRACIMMKALRHLTMGNPSCKALFQEGRALAALGEYNLARNAYLQAQAKQPANKEISDEIISMNKRISKYEEASRDIWARAFSLKNSKSDVRKTPAQLEKEAKEQDFNDKMEDLIRRFKNTSDQQVSFSRKSYSNAQFDATCKLAKEHNLKLTLSPIQEDVLTLSKPDVKFA
The following text describes a protein:
Function:
Part of the ABC transporter complex OppABCDF involved in the uptake of oligopeptides. Probably responsible for the translocation of the substrate across the membrane (Probable). Required for sporulation and genetic competence.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Sequence:
MLKYIGRRLVYMIITLFVIVTVTFFLMQAAPGGPFSGEKKLPPEIEANLNAHYGLDKPLFVQYVSYLKSVAMWDFGPSFKYKGQSVNDLISSGFPVSFTLGAEAILLALALGVLFGVIAALYHNKWQDYTVAILTIFGISVPSFIMAAVLQYVFSMKLGLFPVAGWDSWAYTFLPSIALASMPMAFIARLSRSSMIEVLNSDYIRTAKAKGLSRPAVTVRHAIRNALLPVVTYMGPMAAQVLTGSFIIETIFGIPGLGAHFVNSITNRDYTVIMGVTVFFSVILLLCVLIVDVLYGIIDPRIKLSKAKKGA
The following text describes a protein:
Function:
Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex.
Sequence:
MEACKALICGGGARLHTNDREVVAPSVWAVPWLEVTVRRRLRRRLWWRRWRLRRRPRRRRRKQKMADFLKGLPVYNKSNFSRFHADSVCKASNRRPSVYLPTREYPSEQIIVTEKTNILLRYLHQQWDKKNAAKKRDQEQVELEGESSAPPRKVARTDSPDMHEDT
The following text describes a protein:
Function:
May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid.
Subcellular Localization:
Secreted.
Sequence:
MEEPQLLGFLSSRACSQDNGKVIHINKVHHQPLRVGLSEPVALPCLFLLQPPTHLSPNEAADPPRIKWSKVQSASGQPEDISVLVAKDNVVKVSKGYEGRISLPGYPHRRYNATLLLSAARASDAGLYRCEVVAGIHDEQDLVPLEVTGVVFHYRAASNRYALTFPEAQRACEENSAVMASPDHLQAAFEDGYDNCDAGWLSDHTVRYPITLSRPGCYGDRNSLPGVRSYGERDGTEAYDVYCYARELQGRVFYASSPGRMTFPMAQKYCLSRGAQLATTGQLYLAWKEGLDQCDPGWLADGSARYPIRVPRKKCGGDEPGVRTAYQFPNRTGFPNPSSKFDAYCYKGIWICVHNRHHWGAVSFSVEHDSDVPLLVQNELFPKENEEAIISGDSKEPYSPFSKAGVPLLEDDEQLQLVTAFPDGTWDGKDEREVETSSPVYPGDRYHVVFTEKSTSVDPTQGTSPLVDESEDEVTDVVPHETASPQFPTSAFNPTSHTGQLTTEGSSALAESTRRSIYSGLNGRYFQRRREDEVDADEEAEGSTHLPTLLPVLALAVHRIVDNSIEAAASADHGSTAALRSGPSYALSNEVEGNTTSLLPFPTKEVGEEEQPMTFQSTQRQQRPTDPNPTLLGSPRMTEVEEENDGYFHPSSLLPMDADSGSGEEKGEASAVKEDEGLAWSEEANVTLMADTDPCDNDPCLHGGTCQSNGNISTCNCPRGFTGENCEIDIDDCLSSPCQNGGTCIDEINAFVCLCLPSYGGNLCERDTEGCDHNWHKFQGHCYRYFAHRRSWEDEHNFINGFGHENTWIGLNDRIVEQDFQWTDNSGLQYENWRENQPDNFFAGGEDCVVLVSHETGKWNDVPCNYNLPYVCKKDTVLCGPPPAVENAFPIGKKKEKYSVHATVRYQCEEGFLQRHLPTIKCHVNGTWDRPRVLCTKPRRSHRTRRHHRHRHRQHHRHKSRKDRRKHSKQQQPPHPKADWNEDDGNYF
The following text describes a protein:
Function:
Binds to the promoter regions of RNA polymerase II and III small-nuclear RNA genes, type 3 RNA polymerase III non-coding RNA genes, small nucleolar RNAs and transfer RNA genes. Required for expression of mature 21U-RNAs.
Subcellular Localization:
Nucleus. Note=Diffuse nuclear localization. Concentrated in foci within nuclei of proliferating and pachytene germ cells. Foci localization is dependent on prde-1 activity.
Sequence:
MSDLVMFEPGASTSTDVPTNTDQTAMSTTQVVDALECDTFEGLMNVNETYVEILDSALLSVQQHLDDNLKRQQQLKEEYRLYNRADITKRKVPVHLYMPPYFKDDNNMYPPMSSEAREKQVLKWFDPMMKEEKKWTPSEIKTLRTSVKNALVAHQVQPWCSRRDIVASKLRDADITTSNFDRRQWTMELEDLMRKIAYVREKSEEEVLTASADYTVVPWTAIANFDFKGSRTEWAVKSKWYNELNPKWNKEHWSNEEVEKLKYLRESPKFVSWPMLALNLGTNRTSYQCMEKYKTEVSQHSKEWSQDEDTKLIALTKITSINGHIQWDKVAQCMPGRTRQQVRTRFSHTLDASVKHGRWTDQEDVLLVCAVSRYGAKDWAKVAQAVQNRNDSQCRERWTNVLNRSAHVNERFTLVEDEQLLYAVKVFGKGNWAKCQMLLPKKTSRQLRRRYLQLIAAKLRLAAGFCNAVDAMKSGRRAPEEDELEQEDIVEAEQIPNELMKEVYEKFANENPDMNETPEEFYKRVSALERPAAARIRALKNKPDYQKIQDKINEIVQKHKNAAEIDKELHSSEILSSLTITEVDVRYMIERSKTLTRYYEARQFRKNVDQIGCRVRPIKIDLDPETMPTFDPNDAEDEKQMVIVESLCSVIRAHDVKEWGTKFWNEHRFTAPKYAKRFVENMVINKSKEVAEWYLHVNSKSCNQNDVHCPAKSTLPPTAASFDLHKMLQKARSGLNRLSAEHFYPLDVSLAQQFNFKNDEREGLDGDRRMHIGLSDEVTNSKEYANFYARMRSILLEPMRLGIARESSSDETKRLVRCLAEERACDEEQQVTCDQIRRRRMPDDEIYVTPTSISRELNNGMKIDTTELLANLDKNSAKKIRMKRKIGEVRCDTKIKLLPLVILATVATVAARPARPPRSSAGTPTPSHVSIDTESNISLKVELD
The following text describes a protein:
Function:
Involved in the secretion of glycoproteins and in nucleus architecture and gene silencing.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Domain:
The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.
Sequence:
MTTRKTASSLQLLGKITGTKAGTKQKKMNFINGLIWLYMCVWMVHGKVTQKDELKWNKGYSLPNLLEVTDQQKELSQWTLGDKVKLEEGRFVLTPGKNTKGSLWLKPEYSIKDAMTIEWTFRSFGFRGSTKGGLAFWLKQGNEGDSTELFGGSSKKFNGLMILLRLDDKLGESVTAYLNDGTKDLDIESSPYFASCLFQYQDSMVPSTLRLTYNPLDNHLLKLQMDNRVCFQTRKVKFMGSSPFRIGTSAINDASKESFEILKMKLYDGVIEDSLIPNVNPMGQPRVVTKVINSQTGEESFREKMPFSDKEESITSNELFEKMNKLEGKIMANDIDPLLRKMNKIVENERELIQRLRPLLDLKKTAISDDSFQDFLSMNANLDRLIKEQEKIRQDAKLYGKQTKGHDEIFSKISVWLALLIFIMITLAYYMFRINQDIKKVKLL
The following text describes a protein:
Function:
Transcription termination factor. Binds promoter DNA and regulates mitochondrial replication and transcription. Transcription termination activity may be polarized with highest termination activity occurring when its DNA-binding site is positioned in the reverse orientation with respect to the incoming RNA polymerase. Required for normal topology and maintenance of mitochondrial DNA (mtDNA) levels. Regulates mtDNA replication by promoting replication pausing, possibly by acting as a natural barrier to replication fork progression. Its function in replication pausing prevents unregulated replication that may occur for example by collisions between the machineries of DNA replication and transcription during mtDNA synthesis. This ensures the incorporation of RNA transcripts into replication intermediates at the replication fork and allow for proper fork progression. Shares mtDNA binding sites with the mitochondrial termination factor mTerf5 and thereby may antagonize mTerf5 function during replication to regulate pausing. Likely to function downstream of Dref which activates genes involved in mtDNA replication and maintenance.
Subcellular Localization:
Mitochondrion.
Sequence:
MIRSLLRSFETALKLHAGLNMHPMHCSRRLLFSQYENRASPSRLTSSGTLGSNEAENDYVPYRQDRETGTKTRVLLEALRERFRFTDAELQKIISDELVHRCYRGRSLTLVMDTLQLEGVSRRSFVEYPWLLSLDNKRLELKMQLLKSMDFKDINHFVPFLRLTVPRLRKLVGALNSERDAMPQRNRVYYISEKLDVSPDIVSKYLSKRLFILEMPFEMFEKNLQHMIDYNVSPINVLKDLWAFRYTPKSVQLRLERAKRAKKDKIMPWMVRCPEPILQRSLKLSLDELKVLGEFSSVVEYLAHRLGFSTSEAKAIMDKHPQVHTVRVTKIKEVLDYLLDEAQFTRFEVAQNPRILCHSLKTTKERMEELKSHGCRPSSLVILCRSRREYDKFLQNWISHERNPQSVSEG
The following text describes a protein:
Function:
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
Sequence:
MSRTVFCQYQQCDTEGLDFAPYPGELGQRIFAQIGKAGWQAWLAHQTMLINENRLSPRDPKHRAFLEAELQKFLFERNADKPEGYVDPLGEE
The following text describes a protein:
Function:
Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MGAGASTPSVPPTDSAPAVTCPVDHKTREVWLQQHKASGGAPHPLPGEEEKTKPKLQRPLSTDREVSSIPRAFDASSSASSSQAPAACPSPYAASHGTPSNAEAETGHDQNTGNWIYPSERQFFEALVRKGNTPATTSSASELATTVASIIPIHNAVNERAWKQILEWESLAPSSDPGSKKCGGPKLYSFRGLGVDPQFLSPRARFNSLLGYQKPFDRHDWVVERCDGERVEYVIDFYQGKSSGTDGAAAGLTANAGPGKLSFYLDVRPKLNTFEGWRMRFRRFTGL
The following text describes a protein:
Function:
Involved in efficient integration of the N-module into mitochondrial respiratory chain complex I.
Subcellular Localization:
Mitochondrion.
Sequence:
MPAGGLAAAQSLRHFIYRSHVLGLYRQYLRASRGLGTGSERRDLAVEVRRNFEAQRHVTDLQAIKFLLSEGRKRLEQLQDMLGLQR
The following text describes a protein:
Function:
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome (By similarity). Required for cellular differentiation in neuronal and myogenic lineages during embryonic development.
Sequence:
MPSNMNNKLDPVFSSGFVRREFNDSGIADGKLRTISTSSCATTMSSESYRISLGVGPLWWSDVPVHHRTDHDRASLLTGYSRKSSVDSAGGSLYEASSRASSLSSSQSDCSDLESQPDIHSLCSDDDCQEVLRQILQHDQPVQITIKLHVTEDQYTNWNTILNPVNNLLYVALPKDLPPAGSKQTFISLLEFAEEKLEVDGIVMVMPKDQPDRARLIEAFLFMGFEPLSRKAPQAPPAAINDNENYYFLYSIEE
The following text describes a protein:
Function:
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Sequence:
MTERGQEHRSLTGPGTDRRDRIAPNPVLTPPPRPRTSTRMNALPSPSVPPAGSAGRDVLRTLLERPLPAVMGVLNVTPDSFSDGGDFIAPDLALERARAMIADGVDIIDIGAESTRPYKGAKAVTAEDELARLRPVLSGVVALGVPVSIDSMKAEVVAFALDQGAAIANDVWGLQRDAGMAPLVAARGVPVIVMHNRESVDSAIDIIADMKAFFLRSLDIAAKAGIARDKIVLDPGIGFGKTAEQSMTALARLREFDMFGLPILVGASRKRFIASVSPSEPKERLAGSIAAHLIAAQRGARIIRTHDVAETLQALRVANAIESKQ
The following text describes a protein:
Function:
Contributes to the regulation of alternative splicing of pre-mRNAs.
Subcellular Localization:
Cell junction, adherens junction. Nucleus. Cytoplasm. Note=In heart, localizes at area composita, the mixed-type junctional structure composed of both desmosomal and adherens junctional proteins.
Sequence:
MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERAQQPGMSSGGMVGSGQPLPMAWQQLVLQEQSPGSQASLATMPEAPEVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPLGPDGLPLLDGGPPLGSFADGPLDRHYVLRGGGPAATLSRAYLSSGGGFPDGPEPRDIPSYGSLSRGLGVRPPRTGLLGPGPGDGCFTLPGRREAFPMGSESGPPSGRSLPEHFQAEPYGLEDDTRSLAADDEGGPDLEPDYSTATRRRPEYGRGLRARALEDTADDTGELVEERPPFPAATAPLAQPERGSLGSLDRVVRRSPSVDSTRKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGIKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDADNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEVEPGIPGSAATSQRRRKDDASCFGGKKAKGKKDAEADRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDQRNKDLIGSYAMTELVRNVRNAQAPAHPSAHLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALVASSQSVREAKAASHVLQTVWSYKELRGALQRDGWTKAHFQSASTAKGPKGTPNSGGFDDSTLPLVDKNLDGEKSTTRDVIPMDTLGPDGYSTVDRRERRTLGSDSIGDSSEKELLKGPGPAVCSSDHMEVIGRGPSGTDPVLGPGAPPFCVGLAKPLVYLALPSSLLS
The following text describes a protein:
Function:
Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Subcellular Localization:
Mitochondrion.
Sequence:
MFRTVRSCAVALPTRASTLRAYHSINLINTKPTEDYNPKTKKLLDAAMDLVPSLGFTDQALTLASRRLGYTDTTPLVLPEGPLDLIVYHLRREREKLAVASETAPADPPAAPTTPDFRTKDQRLDDACHELIVQRLKGNIPVIEHLDNALALMVQPQNMAESLSELGALSDEIVHQAGHRSSDFDWYTRRASISAVYAASEVYMCQDKSKNFEDTWKFVKSSLEARRGLQEGVGNVGQWVSFQGIASVMVIRSLMTRL
The following text describes a protein:
Function:
Essential transporter for growth and development under abiotic stress. Mediates shoot branching by promoting the outgrowth of lateral shoots. Required for salt tolerance via Na/K homeostasis, at least partly by regulating SKC1/OsHKT1;5. Necessary for hypodermal suberization of roots, which contributes to formation of the apoplastic barrier.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MATSGHIVVDVGTHEDASAGQPPVAPVPYRLSFTDLSYTVRTRGGRLASLLSRARASTDSPSPSTTRALLNGISGEAREGELFAVMGASGSGKSTLVDALAGRIERESLRGTVTLNGEPLHGRRLRAISAYVMQDDLLYPMLTVRETLMYAAEFRLSRALSPARKRERVDALIDQLGLTSAADTVIGDEGHRGVSGGERRRVSIGTDIIHDPILLFLDEPTSGLDSASAFMVVQVLLDIARSGSVVVMTIHQPSARILGILGRLLLLSRGRTVYAGTPAGLMPFFHEFGKPIPENENPAEFALDTIRELERQPDGAAQLADFNARWQADHRIIETVNAMPLEVAISESVCRGKLVAGTVTGTASSVPTYANPLTVEVWVLIKRSFTNTRRMPELFGMRLGTIMLTGLILATIFLRLDDTPKGVQERLGFFAMGMSTMFYVCADALPVFVQERHIYLRETAHNSYRRLSYVLANSVVSFPPLVILSLAFAVTTFFAVGLAGGGASFAFFALIILASLWAGSGFVTFLSAVVPHVMVGYTVVVAILAYFLLFSGFFINRDRIPNYWIWFHYISLVKYPYQAVLQNEFGDASRCFARGVQMFEGTPIAGMTEAVKLKVLGAISATLGTNMTAATCVVTGADVLRQQAVTDLGKWMCLLVTAAFGFFFRALFYVVLLVGSKNKRK