lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
FYSTFHFIRTVGRIEGWKFLFRCLDKAHSHSTVIWKIWLTVLFVFRILLLGAVGEKLILVSTPTLVYLGHVLHVIHKEEKLRQRKLKEEQDESDNLLQKKTSKLPKYTDTKGKVKIRRSLLSAYMAHIIAKILLEVTFIVVQYYLYGFMLYLRFSCARSPCPHRVECFLSRPTEKTIFSLFMLVVAVVSLILNLIEILYVCGKQICNCTRKKSKNCTTSPTVPLTDVDNFRNEDHEL
The following text describes a protein:
Function:
May play a role in the regulation of cytokinesis.
Sequence:
MKVNSTTEIIKSLLECLSKEISNGEDEDTMITDITELFNLSKEFDVRKEISNKHNEFLNILMNYIIKSTTANGDNNEKLFKFNLTSIRFLRNLCANVSENQNIIISNSNFINFIINQLINENNNIKITLNKKNILTSLYQLLINGIVLNDKTQSLLWSNIYPNNLIILIEKYKDNDEFKLLPTNLMLIYNCILNSKDRMKDLVCNKRLVQLIIELIKEDDTFDHEYNTQNFHWIHLISKSLFINDLFIDLYKSLSDNKYSTELVKSTTESTTESTTTESTDSTTDSTTTTTTGKTNKNQVKLLNLLDSIIHDGDKKNIKEYIEKDSIIDLKTCYFMIDELASLYNLDFARKDLKVETQQLTTSLNQSDFDAIFFFIKIFANITSYTEEMLSLSLSIFKPNQIPTKQQEGEEDPVNQILNDPFSKDSAIDPSASKKFDLNTLLRKKGLVAICIGSLHGNYGSDTNKSSSSSSSSSSSTTTDGETVTSKGFNKNIESQDKGFKIELIRILGNLSYKNRGNQDEIRELGGIEIILNHCRFDVNNPYIKEWSVFAIRNLCEDNVENQNLIESLKVKGVANNDELKDLGLEVGVTENGTIKFKNVPKKEKENNQ
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MENGHMNGVRTHHDRNSWTNGVNGGVAKREGSPDKGKAHANMSGSSVMMNGGGASFMDVDSQPPGGTKFNDLPDEIQHITADIMPLSLLLTRLSQWTHTKLQDEIAYLASKPLPQGVLNGTTNHQSADNHDTSQESLEKKVHLLNFLQDMHSKWVKTLVITEWSRKAAQVGALIDIRVHLLTKQAHYQELFWELIRMKQDLHWAKVPGPDLKTALEVLTTGQASWMPELGYIEPPPITWEEKEAFIDNINTMLSVRLTFDEHEKLPAAFRDYNIANGRVTFKVKGEFEVDLTIGDEDFEQQFWFIDFRFLFTPAPAELSHGVRTFLENKVNTILGDQGLAGCYNYLHEFVLTQKIIEFRRQATELAMGRWVDTLKVEKLNRAMSIQYWLKPPHGLEGPSSQTAKSWILLGVWSGKGVEGDLDSKPSSYISLRWFRDNKEVKDFDIPLNVETISAEKLLTAVIASHVEYILRSISSKLLSKPRFAQKHARLDLEISKEEPQNSSLAVQLFDNDKAVIKIEPLTGFFTMFPRSPVFLKGQMKLNTSSNVAEEGANLMEQLRFDHAVKDLNSRVRSIGWFVCRPPITQEETKTIVYSDASGSREAFKAVWLRKANWMTRQWFVMISMSLGGDQWWLVDLSPPKPNFPAGRLRLFTKMPMTSNQLTLSDTFFRNLSVYAAGMISHITDLRKLHTLKKSHTALELPNHSLPPQVRLPTIYVRLSEMLQQRPGSSSRTLTWAKDFVPIIFKGVRSHTGDQEGPADATAVRRDTPASIRAEARLTVIDRNKFKSLRGNVDHDVVYNHRTGQFSLKLRADMGTPVVDLLADRVQALERLMEFVEAIRLAGSNAIPQSVALREVVFTYSNDPAEPVVGPPQGPRAWNVHLDLPKDAKVVLTLEKGNPHIRALDMLQDMAQSTKTELLPSYLPFSLPLYRVLDRIEDEWESIAAKNAGNVAIVVKAAEWVTVRFTLPAPTTRRLLCLDIKTMGRKGRLLWHVKRTDEKGHERPLNAPQDEFDTLLQRSVWHAHGDGRKTFGTSAAADPKVGIETLLWSISESVKSLVGTLPPPPGTSPHPGGGTQDLQQGPQKTPQEMVAAQAAQAAQAAQAAQGMPPQRPKQQPPTPSQPQQQHRNVNQPQAQAQPQLHTQVQLQQAQVAQLQAQRQAQARANNSSNNNNTFVNRAHPGQPPQQRQSGPQTQAQQQQQRYQIQQQAQAMQRMQQQQQQQAAQQHAQQQGQGPQGQRSVHGQAGPQGVPQGQPGHGGGANGGMGGKNAPVVVID
The following text describes a protein:
Function:
Catalyzes the attachment of tryptophan to tRNA(Trp).
Subcellular Localization:
Cytoplasm.
Sequence:
MIKRAITGIQASGRQHLGNFLGVMQGLKQLQSQYQLFLFVADLHAITVDFEPTMLKDNNLQLVKTLLALGLDYGKVNLFLQSDLMEHTMLGYLMLTQSNLGELQRMTQFKTKKLAQKRNSNNTITIPTGLLTYPVLMAADILLYQPDIVPVGNDQKQHLELTNDLAKRVAKKFKLKLKLPVFIENKDTNRIMDLSNPLKKMSKSNPDQNGVIYLDDSKETIIKKVRKATTDSFNKIRFAKKTQPGVTNLLVILTALLKEEVNHNLSKKIGSDLVKYYQNKSYLDLKNDLSSAVINVIESLKFKKAQITDEMVLKVLNDGKNQAKKVADETLKMFYKAFGLTSNQLFD
The following text describes a protein:
Function:
Photolyase involved in the repair of UV radiation-induced DNA damage. By using blue-light energy, catalyzes the photoreactivation of cyclobutane pyrimidine dimers (CPDs), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. Can repair CPD lesions in ssDNA as well as in dsDNA.
Sequence:
MSLKTAPVIVWFRKDLRLSDNLALLAAVEHGGPVIPVYIREKSAGPLGGAQEWWLHHSLAALSSSLEKAGGRLVLASGDAERILRDLISETGADTVVWNRRYDPTGMATDKALKQKLRDDGLTVRSFSGQLLHEPSRLQTKSGGPYRVYTPFWRALEGSDEPHAPADPPKSLTAPKVWPKSEKLSNWKLLPTKPDWAKDFSDIWTPGETGALDKLDDFIDGALKGYEEGRDFPAKPATSLLSPHLAAGEISPAAVWHATKGLSRHIASNDISRFRKEIVWREFCYHLLFHFPELGEKNWNDSFDAFSWRDDEKSFKAWTRGMTGYPIVDAGMRQLWQHGTMHNRVRMIVASFLIKHLLIDWRKGEKWFRDTLVDADPASNAANWQWVAGSGADASPFFRIFNPILQGEKFDGDGDYVRRFVPELEKLERKYIHKPFEAPKDALKKAGVELGKTYPLPIVDHGKARERALAAYAAVKKTT
The following text describes a protein:
Function:
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
Subcellular Localization:
Nucleus.
Sequence:
MSESELAVIKPEALKTYIWLQCFDGSIQQVEEEVAMFCPMICREIVKNGTGSSKNHAIALPERVNPTSLSLILDYCRFHQVAGRSNKERKSFDEKFVRIETERLCELTSAADSLQLKPLVDLTSRALARIIEGKTPEEIRDIFHLPDDLTEEEKLEPLKNINDDPRIRLLNRLYAKKRKELQERHQRQKLKGVQVQKEQKDERSLDELLCFINGDGGSGGKATKSKKKNKRRKDHAKNPPKADSEPLNAEGAACVVPCKVDSSNVSRLPCQNPDVQDDVEYPFEDADLDDGLDPAMKEELDREVEDFARRLNSVWNESHIGGNGSVQRFPGFNHR
The following text describes a protein:
Function:
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
Subcellular Localization:
Cytoplasm.
Sequence:
MLTKHRILFIGAGRMAEAIFSGLLKTSKEYIEEIIVSNRSNIEKLKQLQHQYNVSTTTDWKQHVTSVDTVVLAMPPSAHEELLAELSPLISNQLVVTVAAGIGPSYLEARLPKGTPVAWIMPNTAAEIGKSISLYTMGQSVNEIHQETLQLLLKGIGTSQLCTEEEVHQLTAVTGSAPAFLYYFAESLIEATKSYGVDEETAKHLVIQMISGSASMLEQTQNPANLREQVTTPGGSTAEGLKTLYEYNFSEAIQKAVEATNKKARGK
The following text describes a protein:
Function:
Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles.
Miscellaneous:
MISCELLANEOUS: Present with 11700 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MFSQIVLLLSAFIYVASATARRGTIKGRLDLAASNITGFVSTRTSFKLYQIGNFSTEYPYTSTTMFQDDEGNFEFANLPLNDGVNETTYYVMYPASMDFNLKPNRILIEFKNLENGTLQLNAFKNFFGREYFPSKDITYPEKLQSMKVHPYITVELLHKAPIRSYLQARNVSIFSTGIVGNILNSRWKLAGVITLIALVVFPIIVEKLDPETARAIREEAKRKQREKYAAVASK
The following text describes a protein:
Function:
May play a role in regulation of gastrulation.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MVPYHIRQYQDSDHKRVVDVFTKGMEEYIPSTFRHMLMLPRTLLLLLGVPLALVLVSGSWILAVICIFFLLLLLRLLARQPWKEYVAKCLQTDMVDITKSYLNVHGACFWVAESGGQVVGIVAAQPVKDPPLGRKQLQLFRLSVSSQHRGQGIAKALTRTVLQFARDQSYSDVVLETSALQQGAVTLYLGMGFKKAGQYFMSIFWRLAGICTIQLKYSFPSA
The following text describes a protein:
Function:
Nitrilase that mediates the hydrolysis of aromatic alpha-hydroxy nitriles to carboxylic acids. Has high activity toward mandelonitrile and mediates its hydrolysis to mandelic acid. Also mediates hydrolysis of mandelonitrile derivatives. Has weak activity toward aliphatic nitriles.
Sequence:
MQDTKFKVAVVQAAPVFMDAPASVAKAIGFIAEAGAAGAKLLAFPEVWIPGYPWWLWLGTPAWGMQFVPRYHANSLRADGPDILALCAAAAEAKINVVMGFSEIDGGTLYLSQVFISDAGEIIFKRRKLKPTHVERTLYGEGDGSDFRVVESSVGRLGALCCAEHIQPLSKYAMYSMNEQVHVASWPSFTLYRDKAYALGHEVNLAASQIYALEGGCFVLHASAITGQDMFDMLCDTPEKADLLNAEGAKPGGGYSMIFGPDGQPMCEHLPQDKEGILYADVDLSMIAIAKAAYDPTGHYARGDVVRLMVNRSPRRTSVSFSEDENAAVTFTET
The following text describes a protein:
Function:
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
Sequence:
MATAKDDANDLPRTKFFLRGKTGIEAMWGPPTSSKQDGKIERDENFDAPGTADIMEFSEDGKLVVLVRTASGFTVRDSENGSVQADVSNPGIHAVAWSPLGSHLLTWQRPQKDSSLGNLIVWETVTGKEVARFNHKSYTRDKWPPLQWSSDETICARQSANGVVLYSGRDIAAGQIGQINLPNVANFSVAPGSAPYKVALFVPEKKGKPASVKVYQFPNSLNLPTATKSFYKAQDVSLKWSPTGSALIIETRTDIDTSGKSYYGETGLFFLESDGDYDCIVPLTKEGAVHDVAWDPTGRGFVVIAGAMPAHATLYDNKALPIFEFGAAPRNHVSWSPHGRFLCLAGFGNLRGDMDFWERNKLKKMGSATSNSATTFAWSPDSRYFATATTFPRLRVDNGFKVFCYDGAGPIHQEERGELYDLKFRPAAQDTYPNRPQSPRRKGEDAGFGSSAAPKATPKPQAYRPPNSTGALAAMMRKEEGGSKKLDRNKYAAPRGGTPTTPGMTAARVIPGMGAAAAPKKLSKSARKKKAQEAAEARAAVEEALAKVGAAPVEEAPAKPTPTELTPEEKAKKVKGLLKKLKQIDTIKAKKEAGDSLNDDQLQKLTTEQALRDEVAELSA
The following text describes a protein:
Function:
Photosystem I assembly factor that assists the proper folding and integration of PsaB and PsaA into the thylakoid membrane.
Subcellular Localization:
Plastid, chloroplast thylakoid lumen. Note=Associates primarily with stroma-exposed thylakoids.
Sequence:
MASSAFAFPSYIITKGASTDSFKSTSLSSSRSLVTDFHLLFSRPISSGPKYQSAKSAKPESPVAINCLTDAKQVCAVGRRKSMMMGLLMSGLIVSQANLPTAFASTPVFREYIDTFDGYSFKYPQNWIQVRGAGADIFFRDPVVLDENLSVEFSSPSSSNYTSLEDLGSPEEVGKRVLRQYLTEFMSTRLGVKRQANILSTSSRVADDGKLYYQVEVNIKSYANNNELAVMPQDRVARLEWNRRYLAVLGVENDRLYSIRLQTPEKVFLEEEKDLRRVMDSFRVEKI
The following text describes a protein:
Function:
Lipoyl amidotransferase that catalyzes the transfer of lipoyl moieties from lipoyl-protein H of the glycine cleavage system (lipoyl-GCSH) to E2 subunits of the pyruvate dehydrogenase complex (PDCE2). Unable to catalyze the transfer of octanoyl from octanoyl-GCSH to PDCE2. In vitro, it is also able to catalyze the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes but this reaction may not be physiologically relevant.
Subcellular Localization:
Mitochondrion.
Sequence:
MILRLSSRACVLSGSVRLKSTLASFFDDLGKSGIILKSASSGIFENLALEDWIHDHVDLQNRSLLLLWRNSPVVVIGRHQNPWQECNLPATRRLGIPLARRRSGGGTVFHDFGNINMTFFTSKKKYDRHRNLKVVTSALKALRPNLDVAATDRFDILLNGHYKISGTAAKLGRSSAYHHCTLLCSVDRSVLSSVLKSNTAEVIKSNATPSVPSPVKNLLEVDPTFDSSTIMEAIASQYNSEFGFDSPVITVDPTHEALMPGIHKMAHDLQTWEWIYGKTPKFSVCTALVVDDVNIKLDMDVRNGTVERCALEIPADWLSPEIVNELISTLKGSRYCPNETAVLVAAFMRTRSMTDNVAEKIHRLCEEMLSVM
The following text describes a protein:
Function:
A probable role in capsular biogenesis. It is likely that the caf1A molecule binds F1 antigen subunits during the extracellular secretion process.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MRYSKLFLCAGLTLATLPCWGRAYTFDSTMLDTNSGESIDVSLFNQGLQLPGNYFVNVFVNGRKVDSGNIDFRLEKHNGKELLWPCLSSLQLTKYGIDIDKYPDLIKSGTEQCVDLLAIPHSDVQFYFNQQKLSLIVPPQALLPRFDGIMPMQLWDDGIPALFMNYNTNMQTRKFREGGKSLDSYYAQLQPGLNIGAWRFRSSTSWWKQQGWQRSYIYAERGLNTIKSRLTLGETYSDSSIFDSIPIKGIKIASDESMVPYYQWNFAPVVRGIARTQARVEVLRDGYTVSNELVPSGPFELANLPLGGGSGELKVIIHESDGTKQVFTVPYDTPAVALRKGYFEYSMMGGEYRPANDLTQTSYVGALGMKYGLPRNLTLYGGLQGSQNYHAAALGIGAMLGDFGAISTDVTQADSQKNKQKKESGQRWRVRYNKYLQSGTSLNIASEEYATEGFNKLADTLNTYCKPNTRNDCRFDYAKPKNKVQFNLSQSIPGSGTLNFSGYRKNYWRDSRSTTSFSVGYNHFFRNGMSLTLNLSKTQNINKYGEKTSELLSNIWLSFPLSRWLGNNSINSNYQMTSDSHGNTTHEVGVYGEAFDRQLYWDVRERFNEKGRKYTSNALNLNYRGTYGEISGNYSYDQTQSQLGIGVNGNMVITQYGITAGQKTGDTIALVQAPDISGASVGYWPGMKTDFRGYTNYGYLTPYRENKVEINPVTLPNDAEITNNIVSVIPTKGAVVLAKFNARIGGRLFLHLKRSDNKPVPFGSIVTIEGQSSSSGIVGDNSGVYLTGLPKKSKILVKWGRDKNQSCSSNVVLPEKTDISGAYRLSTTCILNN
The following text describes a protein:
Function:
Required for root meristem maintenance after germination. Involved in phloem translocation, starch accumulation and flowering. Promotes flowering in the photoperiod pathway. Regulates long-distance movement of FT from leaves to the shoot apex through the phloem stream.
Subcellular Localization:
Cytoplasm. Nucleus. Endoplasmic reticulum. Note=Mobile through plasmodesmata.
Sequence:
MLCASQASTTTLCSTMDQTSQPSSSSSATIRLGGRAIDRHNPIIRDGRRLTPPPSPNLNPSSSSSSTYHTPLMTRLGLESSEQKRLAKRKSKKGDSDVGKSPVSCFSSDTPQGSSRYLLSNPVFFDGFVDSDPIPIPIDEPEITKADDLNNFHEDRLIINASKYLSTSASFLEKKQPDFFEGFLDYEPVLSPDNPFSEPTKASPTASLSSLEDKDVSSPDFKFSPPPPPPPSPPQSSPPSPPEKNSSSDQVVVLRVSLHCKGCAGKVKKHLSKLKGVTSYNIDFAAKKVTVTGDVTPLTVLASISKVKNAQFWPEIIQK
The following text describes a protein:
Function:
This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression.
Subcellular Localization:
Cytoplasm.
Sequence:
MAAVNLRHIEIFHAVMTAGSLTEAAHLLHTSQPTVSRELARFEKVIGLKLFERVRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLPVFSQSFLPQLLQPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHTPAGTERTELLSLDEVCVLPPGHPLAVKKVLTPDDFQGENYISLSRTDSYRQLLDQLFTEHQVKRRMIVETHSAASVCAMVRAGVGISVVNPLTALDYAASGLVVRRFSIAVPFTVSLIRPLHRPSSALVQAFSGHLQAGLPKLVTSLDAILSSATTA
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSLFPCMKLRKLFQMTRRRFASGGDGIRLMVADRQVVGHGINGRPIYFDSPDCPFPAIRYREVSPELCALREKELDDWKKLSLDEKKQLYRYSFCQTYAEFQHITPEWKMCLGVALWLVSIGIAISITMKTVLYGKLPDTFNDERQSAQLRRIIQLQMNPITGLASKWCYRENKWK
The following text describes a protein:
Function:
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
Miscellaneous:
MISCELLANEOUS: The reaction proceeds by a bi uni uni bi ping pong mechanism.
Subcellular Localization:
Cytoplasm.
Sequence:
MTKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRESVSTNDITIVSVFVNPLQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDMYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQMVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTEYLESHISERIEEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE
The following text describes a protein:
Function:
Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine).
Sequence:
MAELTSTLGTIIPTALSDIFHGFVKSKVLFTACELGIFDVLCDKHSAEHVAENVKPSCKTGSTRRLLDTLVAMQLLVKEMDSDPPVYFNSQTAEAFLTRKSPKSLISYFEFLHATDYKLFDNLKHAVVEEQPQWQRAFDQPASEIYKIVHSNKEELVRIYSRFDCVHRLEAPGVMSAFDLNPFKHMCDLGGGTGCFSYEACKQYPALKITIYEMQPILDVAPAFKPTIADCPNQSNVTYVAGDFFKDPLPVADLYFLAHVLHNWAEEKVDLLLSKVFAVLPPGGGILLGEVLLPVDEPNPQLSAPFLDLTMLVTCESGARDRSGPEYKRLLERHGFQDVRMKSLPGAKTTDAVFARKP
The following text describes a protein:
Function:
Plays a crucial role in forming the pre-replicative complexes. Interacts with the origin recognition complex (ORC) and MCM2-7 helicase complex leading to the linking of those complexes and loading of the replicative helicase MCM2-7 onto the pre-replicative complexes. Required for the initiation of DNA replication and then actively participates in the suppression of nuclear division.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MSAIPITPTKRIRRNLFDDAPATPPRPLKRKKLQFTDVTPESSPEKLQFGSQSIFLRTKALLQKSSELVNLNSSDGALPARTAEYEQVMNFLAKAISEHRSDSLYITGPPGTGKTAQLDMIIRQKFQSLPLSLSTPRSKDVLRHTNPNLQNLSWFELPDGRLESVAVTSINCISLGEPSSIFQKIFDSFQDLNGPTLQIKNMQHLQKFLEPYHKKTTFVVVLDEMDRLLHANTSETQSVRTILELFLLAKLPTVSFVLIGMANSLDMKDRFLSRLNLDRGLLPQTIVFQPYTAEQMYEIVIQKMSSLPTIIFQPMAIKFAAKKCAGNTGDLRKLFDVLRGSIEIYELEKRFLLSPTRGSLNSAQVPLTPTTSPVKKSYPEPQGKIGLNYIAKVFSKFVNNNSTRTRIAKLNIQQKLILCTIIQSLKLNSDATIDESFDHYIKAITKTDTLAPLQRNEFLEICTILETCGLVSIKKTKCKGKTKRFVDKIDVDLDMREFYDEMTKISILKPFLH
The following text describes a protein:
Function:
Receptor tyrosine kinase which mediates actions of insulin. May be required for forelimb regeneration.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MGQGVLRGEGHPNNNPNSKVGWKSLVGIITIFMLILCDQSDGKICYSMDIRNNISQFSMLEDCTVIEGHLQILLMFTSKPENFRGLRFPKLTTITDYLLLFRVYGLESLKDLFPNLTVIRGTRLFFNYALVIFEMVHXKEIGLYNLMNITRGSVRIEKNNELCYLSTIDWSIILDSVEDNYIELNRDNKEECGDVCPGTVKGKSKCKHTLVNGALVERCWTQDHCQKVCPSDCKGSGCLPDGQCCHPECLGSCRKPNDPSECTACRHFQNEGVCVTACPKGSYQFQGWRCIDFNTCQELNSRCQNSRDNSCPPYVIHKGECMPDCPSGYIANSTTRTCTPCAGPCPKVCTIFQNVKTIDSVTSAQELRGCTVINGSLIINLRGGNNIATELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGEVLEAGNYSFYALDNPSLRQLWDWHKHNLTIIHGKLFFHHNPRLCLSQIHQMEEVTGTKGRQDKNDIATKTNGDQASCEDNLLTFNFIKTSHDMVLLRWDAYWPPDYRDLLGFMVHYKEAPFQNVTEFDGQDACGSNSWTVVDMDAPERSADGKTQSPGCLLRSLKPWTQYAVFVKTLVSGSDEGRTYGAKSKIIYIRTNETIPSVPLDPFSVSNSTSQIILKWKPPSEPNGNVTHYLVYWQEQPEDSDLYEVDYCNKGLKLPSRTWTPPTEIDENGNENQTEHTSVNKCCPCPKTEFQIQKEQDESAFRKTFENYLHNEVFIPRPVRKRRDLFGVANGTLPDPVTAPPLFNVSSTRAPDEPEPKIYSQKVWFKESVLISGLKHFTGYRIEIHACNHELSMGCSVAAYVNARTMPEATADKVVGPITYEYVEPNIIHLKWQEPKDPNGLIVLYEVHYSRVGGIEEVITCVSQKQYNTDKGGKLRVLTPGNYSVKIRATSLAGNGSWTEQAYFQVPDHPHSNIVKIITGPIIAVFLLLIVLVYCVVQKKKDAEGPAGPLYTSSNPEYLSASEVYIPDEWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVNESASLRERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYLRSLRPDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVADDYAVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLKDDLRPSFQDVSFYYSDENKPPETDDLEIDFENMESTPLDPSSCSLRDQSSRTNIYEEHIPYTHMNGGRKNGRILSLPRSSPS
The following text describes a protein:
Function:
The GINS complex plays an essential role in the initiation of DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MDDAYYSLDQLLAENQKIPCIFNIAVPGMGYLEGTNERDIQPYTPIEIPFWLASILSQQDNPEDESQNYLTIQIPKAFNLQIRNALSASTKNVNLKNLAANSGGGWYESGMALLDMIEDHKLKIVLHKTLFDRLPDIMDLASRPPLSSGEDRSTSTNTTSSHNNHDELSVGSDSWEKEILWTGQLMTKKFTDWEKGRIICL
The following text describes a protein:
Function:
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
Subcellular Localization:
Cytoplasm. Endosome.
Sequence:
MNRFVWCDENLRPDEVVLRKQPGVALYDGDRKSPFVGGELVLSSHQVYWVGSSERQRLGLHLSLVIFIEEQSATWSKSPKIVAHLSAPSEDKHVGAVQSSPFNYVRFSFRSGGASEFYQEMQKALQKKDWLKMPTVDSRGKKIRTGIVGIERQIQAKHDEADKNISAAFEDLSKLMDMAKEMVFLSKSISQKLKEKGSSLTDDETITFKSHLLSLGISDPVTKSMYGSGSTYHKELAKQLAQVLEQHVQLLSPEDLLNACKMMEALDLPLRLQVFPSGVTVLRLATQSDEKLAAETRQLLDEHGSLSAEDLSPLIEIPVILAKERLLSAESEGLACRDDSVEGLRFYPNFFLERCN
The following text describes a protein:
Function:
Required for the uptake of Fe(3+) ions. May participate in the transport of electrons from cytoplasm to an extracellular substrate (Fe(3+) ion) via FAD and heme intermediates (By similarity). Involved in iron homeostasis.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MNLKSIVSWFKEHLPSFDVDVDKHFRTLRVRKYSQICLLISFIIICVIIPLMNYLLLTDKFFKICHHLKHHVFNRRSWVHKTHMYHKQSLQLCLICFVFTSFFVIQGANGDLLEITKRMGRISVALMPPLLFLTLRPSPLPHTLYLALLPLHKWISRIVVLESILHTWFYLYYMYINDTLYVKMRKLPNIYGVIALGLFLLIAITSVRYARRWSYRVFYYVHYVSTWLILVFLHYHARPGISYYTTLNVLILTGQIVYRLHITNVTRVTIVPISSSLSLLEFPLTDLPKKPILPGGHLRINIYHRNFLRRFFSHLIPFQHPFTIASIPSDNLVRLIIRNGHFPLRTNEKYYITGAFEPELSFISKPTVPFNITTKSSKNPFRNNSSALINSPLNFLIKAQRVFMCVGGSGISFGLPLLRILNFNGVNVRLLWVSRDYKDLEVLNHFKNNFEGMEIYISGTEGNEQDIEIDYIDYHDCAADINDEVRSISSSGRVSELGDNSMLSDGNPQPTEPNENTALLSKKSTLRNHHPPKTSDIPDINADDEIDFTYAFSRSKSRKNTAQGTLTTHSSFNGSSVFRQPKIIEPPAQDPCLEAAPKKIRIPAGVKVFFGRPTLGDKDYEWCLQTECDAETDSIQCCRWANQGRDHAEYLSQVWVLAAGPRGLIESTKRWATDGGLHFHGESFAL
The following text describes a protein:
Function:
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Subcellular Localization:
Nucleus.
Sequence:
MTDTQPRKIRKVSTQEQIEDYEKLRQRIKNHFKDALKGKGSSMSLHYIDEITELYKRVQSQKVKDTRVHLEDSEVFKEASDFAALNARNIVFDDSGIALDDKEFFKCLRRFAVTDPSLLSRNDIGDNDGNNSNDEDDVEDDDSDEEEEAIADEYTFNKTNWLKLGILYHQVSKKSISVDFLNGPLKAEKRKIVRARNVDDTKGSGMAKTARQVQASDISGNQEQNTANMVKSVYQTYIEKYDGNGVNLFKFFINPRSFGQSVENLFYTSFLVKDGRLKLYVNNDGMPCIQRVSSDEIREAQLESNKIFASHHIASFNYKAWKKYTQLYNIREAFLGHRDEPEDQMPPEDIIDYNDEEPIPSSQRRDSNSSD
The following text describes a protein:
Function:
Transcriptional repressor of gene expression involved in embryonic pathways, such as LEC1, ABI3, and FUS3. Repressor of the sugar-inducible genes involved in the seed maturation program in seedlings. Plays an essential role in regulating the transition from seed maturation to seedling growth. Functionally redundant with VAL1/HSI2.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to a competing donor splice site.
Subcellular Localization:
Nucleus.
Sequence:
MESIKVCMNALCGAASTSGEWKKGWPMRSGDLASLCDKCGCAYEQSIFCEVFHAKESGWRECNSCDKRLHCGCIASRFMMELLENGGVTCISCAKKSGLISMNVSHESNGKDFPSFASAEHVGSVLERTNLKHLLHFQRIDPTHSSLQMKQEESLLPSSLDALRHKTERKELSAQPNLSISLGPTLMTSPFHDAAVDDRSKTNSIFQLAPRSRQLLPKPANSAPIAAGMEPSGSLVSQIHVARPPPEGRGKTQLLPRYWPRITDQELLQLSGQYPHLSNSKIIPLFEKVLSASDAGRIGRLVLPKACAEAYFPPISLPEGLPLKIQDIKGKEWVFQFRFWPNNNSRMYVLEGVTPCIQSMQLQAGDTVTFSRTEPEGKLVMGYRKATNSTATQMFKGSSEPNLNMFSNSLNPGCGDINWSKLEKSEDMAKDNLFLQSSLTSARKRVRNIGTKSKRLLIDSVDVLELKITWEEAQELLRPPQSTKPSIFTLENQDFEEYDEPPVFGKRTLFVSRQTGEQEQWVQCDACGKWRQLPVDILLPPKWSCSDNLLDPGRSSCSAPDELSPREQDTLVRQSKEFKRRRLASSNEKLNQSQDASALNSLGNAGITTTGEQGEITVAATTKHPRHRAGCSCIVCSQPPSGKGKHKPSCTCTVCEAVKRRFRTLMLRKRNKGEAGQASQQAQSQSECRDETEVESIPAVELAAGENIDLNSDPGASRVSMMRLLQAAAFPLEAYLKQKAISNTAGEQQSSDMVSTEHGSSSAAQETEKDTTNGAHDPVN
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MPCGRREVDLCTMILEDHFGPTVARVGQMCLREKLTLGGVIVAMQRVKGGEEKIPPKKVRRALSVLEQHNLLTIGLDSAYRATYETNPDAVQMMMTFPRACLTAKKLYGSAAEAICEELASKGRLSCSEAIRRVRERLELPAAELKQKFCWLAESQFLVRCPPIESKCRGTPVYAAVWEKFAMPDEIAEMPDTTEEEAAKQAACSMEEDIKPDINLLKASRKRKAPIAEVKKEETKKKADPDASVLWQINISRFRRYVRDEIVLEQVCGRMRSNDETGNSEKSAQNVEMALRALLKVAELKSPNPDSNQTPPITLMDVVRAAKEAEMTITKQDLDWAFALIVDDSRGIVRKAGDSGGGLFVLDFDKALLLAVDSHVDSLIREQIDSKAVRIRRLIRARGYLEEETIDKTVMMSAKQTRDLLYSMLEENYVCVKPIGRTNDFAPARTIGLYYVDQPQTVRTLIESTCMMLRNIIVRRLQLEKDSKHLLERQLKMVNIMNGIDASQNIDEEEKRQQKAEVEDMYMPADVRRDLEIFQKNLSLLHTSEIEIEKVLFTFRAYLKSVTTLRFQPPQ
The following text describes a protein:
Function:
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
Subcellular Localization:
Nucleus.
Sequence:
MDEVVFYIAQGDPADKHSQESYGYVTSIHSSKQYASYRQADSHINGTAITGIGPGERIFTAVPNKALINVYSWGKESVDQRIPIPEALTCITLINHPNGSNNNSDNDDNQLYKLPNYRVPWLLAGGSKSGKLYIWELSSGNLLCVRDAHYQGITTIKGSSCGTFLITGGEDARCLVWNLAELISIYDKSDHQVKPYWQITDNTLPLTDLCLNDTHNINDLKLYTTSEDSTVRIYDIVTKSLLTTFILPSSAECITKDPANRALYVGLNNGLVRSIPLYSINSHTSVLESIGGMNKIITVDADQNLKETFVAHQQKTKTGDDKPVVVTKLTISFDGTSIISGDSEGRVFVSDIVTKQVVKSFTPCNSPIAYIAVETVPDDFVNNLATSTTTNKADKKHRMIPQFKRVLASTNSEEHQIFLDIPGKTTATTNATGNIDFATWLQSKQSEELQFKNLSGINSIVKQVGNENVSDLEEKLQRVSQAYTELRNKHEELIKEHAKLLDKLE
The following text describes a protein:
Function:
Synthesis and degradation of fructose 2,6-bisphosphate.
Sequence:
MALTLNTASEQNNLTQTPLLKIWVPWMGFNLNRRRGSSVPQFCNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGQYRREAVKTYKNFEFFKPDNEEAMRIRKACASAALKDVAVYFSKENGQVAVFDATNTTRERRAVINSFAKERGYKVFFVESICDDPEIIAENIRQVKFGSPDYIDRDEDEAMEDFIKRIDCYKTSYLPIDDEKDRYLCSLRTIMMHSMILCISKFSLLFLLVSRNLSYIKIFDVGSRYLVNRVRDHIQSRIVYYLMNIHVTPRSIYLSRHGESELNLLGRIGGDSSLSPRGQKFASSLASFIRGQRIKDLKVWTSHMKRTIQTAEALGVQYEQWKALNEIDAGVCEELTYEEIQENFMEEFALRDQDKYRYRYPKGESYEDLVHRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKPADELPYLRCPLHTVLKLTPVAYGCKVESFYLNIEAVNTHRERPKVSLLQFTCRMMHFHQGTTSLVLVQS
The following text describes a protein:
Function:
Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate (Probable). This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA).
Sequence:
MKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLQSLNFNQFNLVEAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVEYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGFEGKKKINAIMTKFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSPKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPNFDDVAQKINAMIFS