lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
Sequence:
FHQKICSFLKRHKNKFIFTGVFLGGVIGSLKYAEYKLNSFVAEDQKKIMERKKQEKAFDQVQLHACSLVEVMLDSVLKKVLMLNDTEVILRRLKDKEYGKKLELWNQLKVGVFSRLVAGIYCLNLVTITVQVQLHQLAARGDVQTYNENMAVQVFLSLCHKHMLSEGIAQVSELCHKITSDIIGSMPLQHHVGGENIETALRSVFSCLMREMKIKSRNTELEGAFHPALPSYNTDDEFSQNEKLPQNWLELTFDILESSDCSDVFFECFRESVTFIAEAFTANVENMAISSKSSYIKDEDILPLSIPLAKALPLLNTKLKSVYSADFLQRLMINPIMGKFAFNVYKS
The following text describes a protein:
Function:
Involved in pre-mRNA splicing. As a component of the NTC complex, associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation.
Miscellaneous:
MISCELLANEOUS: Present with 1430 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MPSLRDLSLERDQELNQLRARINQLGKTGKEEANDFVGLNISNEPVYDTVIQTGQSSNATNSFVQETIQKTKQKESGQPYIIPQKNEHQRYIDKVCETSDLKAKLAPIMEVLEKKTNEKIKGIIRKRVLQEPDRDNDDSG
The following text describes a protein:
Function:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSRFFANGSESESESSEEEIQATNFNKASAFQFSDDEEEVKRVVRSTKEKRYENLTSIIKTIRNHKKIKDIPNTLSSFEDLTRAYQKALPVISKEENGITPRFYIRCLAELEDFINEVWEDREGRKNLSKNNSKSLGTLRQKVRKYIKDFEDDLSRFREAPDQESEAEDEVVALESDGGDAGDDSDAGVKPTEAVPKAVKSAPAKAAPADDDDSDDSIDWDSDSESETESSDDENQYQNMRERFLKRTTEKEEKDDDKRKDKRKEQKTKIRKRAEDDEDGEWETVVKGHVVEKPKMFEKDAEIDVPLVLAKLLEIMSARGKKRTDRRLQIDLLFELRDISDQHNLGTAVSVKIHFNIISAIYDYNQKISEPMKLEHWALLLEVMQSMMKLLLANADIIMSESVAEEHEEYATSPFYVRGCPLAAVERLDDEFVKLLKECDPHSNDYVSRLKDEVNVVKTIELVLQYFERSGTNNERCRIYLRKIEHLYYKFDPEVLKKKRGELPATTSTSVDVMDKLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQGNVKDAHHCLVDLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQMPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESDRVREMLTKFIKEESLRTYLFTYSNVYTSISIPSLAQMYELPVPKVHSIISKMIINEELMASLDDPSETVGMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDRGYNRNQNNQGGNWLGQRRDRNNRNRNQRGHHKNNQDRQQQQQQQVQTIDEE
The following text describes a protein:
Function:
Acts as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi (By similarity). Required for vesicle trafficking involved in plasma membrane protein composition. Probably involved in pollen tube elongation and other polar growth. Confers basal tolerance to long-term heat stress and osmotic stress, by acclimation of the plasma membrane.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Localized in the GARP complex in the Golgi and post-Golgi compartments.
Sequence:
MDKSSALEYINQMFPTEASLTGVEPLMQKIQGEIRRVDASILSAVRQQSNSGTKAKEDLADATRAVEELSHKIQEIKSKAEQSEAMVQEICRDIKKLDFAKKNITTTITALHRLTMLVSAVEQLQVMASKRQYKEAAAQLEAVNQLCNHFEAYRDVPKITELREKLNNIKQILKSHVFSDFSSLGTGKETEETNLLQKLSDSCLVVDALEPSVREELVNNFCSRELTSYEQIFEGAELAKLDKTERRYAWIKRRIRTNEEIWKIFPASWHVPYRLCIQFCKQTRKQVESILVNMKEKPVVAILLLALQSTVEFEKELEKKFGGGVPTKDIEDDIEEIGTWEDNSQNISKIRKKYEKKFAASQETEENGFQQEKTGNKDLSVTGAGFNFRGMISSCFEPHLTPYIELEEKTLMDDLEKIVQEESWDVEDGSQNNVLSSSTQLFSNIKKSLKRCNTLSKNQTLFNLFKVFQRVLKAYATKLFFKLPKGGTGIVAAATGMDGQIKVSERDERVICYIVNSAEYCHKTSGELAENVSEIIDPHYADGVDMSEVQDEFSAVITKALVTLVLGLETKFDTEMAVMTRVPWSTLESVGDQSGYVNGINTVLSGSIPVLGKLLTPVYFQFFLDKLASSLGPRFYANIFRCKQLSETGAQQMLLDTQAVKSILLEIPSLARQTSTAASYSKFVSREMSRAEALLKVILSPIDSVADTYRALFPEGTPMEFQRILELKGLKKADQQSILDDFNKHGPGFTQQSVAAAMPQPMPTPPAPPLAITNPATAAGFIANSEDVLTRAAALGRGAASTGFKKFIALTEAAKDRKDGPLRRLFNA
The following text describes a protein:
Function:
Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation. A member of the RNA-directed RNA polymerase complex (RDRC) which is involved in the generation of small interfering RNAs (siRNAs) and mediate their association with the RNA-induced transcriptional silencing (RITS) complex. RITS acts as a priming complex for dsRNA synthesis at the site of non-coding centromeric RNA.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGKVLLELHSVPWNEEGLSDNARLYSFLEFVSPKIEELKYRKLLLEKLQTHIREVVLDAELQVYGSMYIGTTLSISDVDVSLKSPRVGELEKRRVTMVLRKYLDADADFHSSARVPRINLVDVSGIGVDLTFGNDKACRTAELQKAYNEEHPIFGRLLMLLKHWLFERDLENVHHGGIASCALSYMLIGWLEMRFHKKGIDSEVQPIRALLQKFFYFWGVEWTYELFVLRPLTGQIVPKLQKGWLNEVQPNLLSIEDPIDRNNDIGKQSFQISMIKAAFVASANELLSDKTWFSTFAITEDEMFLCKQFENVINTKRSLVEGYDSDTESDELQAGG
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
Subcellular Localization:
Cytoplasm.
Sequence:
MAAALRRGRALGSRPSGPTVSSRRSPQCPVAQEGLRARSRPRVAPRSLARCGPSSRLMGWKPSEARGQSQSLQASGLQPRSLKAARRATGRPDRSRAARPTMDPSAHRSRAAPPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGGVGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICDCCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPLSLLAGTLSPGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYRVGHKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVLREMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGDVVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCLVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAQDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQHHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFQERQAGGGAAPGPRQTLGTPNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSKKLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAPCGSALSACPICRQPIRDRIQIFV
The following text describes a protein:
Function:
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLDNCKRLLFRKFPCFLSMAPSPLFLTQTPRLLDEFLKGGVVMFPLLLLSILALTTAFERGWFWSRLLIQEDQVVRDVLDAAVEDLVKAREIAEHARHLAIGRFLLAPLKLRHPSPETFRLAMEATADKEFARMRRGDKLLETIIALAPLLGLLGTVTGLIRTFNNLNIGGGGSSAEATQAASGIGEALITTAAGMMVAIFALLVFRVLVSLQSQQMDYFAAVGSELELIYREVWYEPHQPMPNLLMAARIAEP
The following text describes a protein:
Function:
May be a cytokine receptor for GPR15LG. May be a tumor suppressor; together with GPR15LG has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (By similarity). May play a role in breast tumorigenesis.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MKLALLPWILMLLSTIPGPGFTAGAQGSCSLRCGAQDGLCSCHPTCSGLGTCCEDFLDYCLEILPSSGSMMGGKDFVVQHLKWTDPTDGVICRFKESIQTLGYVDDFYQVHCISPLLYESGYIPFTISMDNGRSFPHAGTWLAAHPYKVSESEKSQLVNETHWQYYGTSDTRGNLNLTWDTSALPTPAVTIELWGYEETGKPYSGNWTSKWSYLYPLATNIPNTGFFTFTPKPASPQYQRWKVGALRISSSRNYPGEKDVRALWTNDHALAWHLGDDFRADSVAWARAQCLAWEALEDQLPNFLTELPDCPCTLAQARADSGRFFTDYGCDIEHGSVCTYHPGAVHCVRSVQASPRYGSGQQCCYTAAGTQLLTSDSTSGSTPDRGHDWGAPPYRTPPRVPGMSHWLYDVISFYYCCLWAPECPRYMKRRPSSDCRNYRPPRLASAFGDPHFVTFDGTSFSFSGNGEYVLLETTLSDLRVQGRAQPGRMPNGTQARGTGLTAVAVQEDNSDVIEVRLAGGSRVLEVLLNQKVLSFTEQNWMDLKGMFLSVAAQDKVSIMLSSGAGLEVGVQGPFLSVSILLPEKFLTHTRGLLGTLNNNPRDDFTLRNGQVLPLNASAQQVFQFGADWAVSNTSSLFTYDSWLLVYQFVYGPKHNPNFKPLFPDETTLSPSQTEDVARLCEGDRFCILDVMSTGSSSVGNATRIAHQLHQHRLKSLQPVVSCGWLPPPANGHKEGLRYLEGSVVRFSCNNGYSLVGPESSTCQADGKWSMPTPECQPGRSYTVLLSIIFGGLAIVALISIIYMMLHRRRKSNMTMWSSQP
The following text describes a protein:
Function:
Chemotactic transducer for aerotaxis.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MRNNQPITQHERVYPAEQRLITTTNLKGIITYCNEAFIDISGFSREELMSAPHNLIRHPDVPPAVFAHMWTTLKAGRPWMGIVKNRCKNGDHYWVSAYVTPIYDQGAVVGYESVRVKPTAEQIQRAEALYRRLGAGKPAIPRRDRWLPVLLDWLPFILISQIGFLIGIWLNSWWGFILAGLLAVPLGLAGLRWQKRGLKRLMRLAEQTTSDPLIAQMYTDSRGDQARLEMAILSQDARLKTCLTRLQDTAEYLTEQARQADTLAHHSSAGLEQQRAETEQVATAVNEMAATTQEVANNVQLTADATQKANELTSRGRDIAAETRNAIQRLSESVGETGAAVSRLAQDSNEIGGVVDVIKGIADQTNLLALNAAIEAARAGDQGRGFAVVADEVRSLAQRTAASTEQIHHLIAKLQNTANDAVHTMESGLQQAEAGVQRVLEADSALVGISEAVSNITEMTTQIAAAAEEQSAVAEEINRNISTIAALAEQTSDEALRTAKLSEELTTTAQSQYSLVERFNR
The following text describes a protein:
Function:
May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Sequence:
MGSCARLLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGRKLWADTTCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGAICTSKYSSPFPCTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGTHVEVNVKIKKVLKSTKLKIFRGKRTLYPESWTDRGCTCPILNPGLEYLVAGHEDIRTGKLIVNMKSFVQHWKPSLGRKVMDILKRECK
The following text describes a protein:
Function:
Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. The nucleocapsid is bullet-shaped with the tip containing 8 turns of a conical spiral before reaching the helical cylindrical trunk. Nucleocapsid assembly is concomitant with replication, therefore viral replication depends on the intracellular concentration of free N, termed N(0). All replicative products are resistant to nucleases.
Subcellular Localization:
Virion. Host cytoplasm. Note=The nucleocapsid is synthesized in the cytoplasm, and is subsequently transported via microtubules to the cell periphery. About 1240 copies of N are present in the virion.
Sequence:
MSVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKALDGVLPDGVSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTPDDSTGGLTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK
The following text describes a protein:
Function:
Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
Sequence:
MFDITPIRVFGTSSIGVFIATNNTVTFIPPDVPEKIDDAVRNTLRTSVARFTVARSPLLGIFTVVNDNGVLLPPLVLEEEVRLFKALGLNVDIINTKYTAISNLILAGNKVALVSPLLEPSARKVVADVLGVEVIVDTIAGNPLVGALAVLNSRGLLVAPEATDDDLKKLSEYFKVRVDVGTVNRGKSFLRGGIVVNDNGALVGDETAGPELMRMQQVLG
The following text describes a protein:
Function:
DNA-binding protein that recognizes sites within both the enhancer and the promoter of rRNA transcription, as well as upstream of many genes transcribed by RNA polymerase II. Has a role in the termination of RNA polymerase I catalyzed transcription.
Subcellular Localization:
Nucleus.
Sequence:
MDTSVLNPELQIHGFIGVDSLQSSRKRKNDFDDFPLNKGLKTNNNDYSGSIEPKFSPALSIKEDGKNDRNFEALMSLQAQDSNLSEQNTSIHLDALASSSIALGNDNVDSSAFLSKVNKGVNAMRNSTSNQTNDSILISPSEITNMDPFLKGSARWTAEHWDYLERRMQNFCQTYSLDHTQVADSLHEKRLHGPLSSLVKLLVQEMPSFTRRTILRHLRALYNIPGYEKYSRKNSSGRGDFGVQETAIISQEVHNFIMDQGWSEYQFCNQIWAGKCPKTIRMFYSNLYKKLSHRDAKSIYHHVRRAYNPFEDRCVWSKEEDEELRKNVVEHGKCWTKIGRKMARMPNDCRDRWRDVVRFGDKLKRNAWSLEEETQLLQIVAELRNREDLSSDINWTLVAQMLGTRTRLQCRYKFQQLTKAASKFELQENVWLLERIYDSLLNNGGKIHWENIVKEANGRWTRDQMLFQFINLKKMIPSYDNLPLLEATKSAIDDFKVVLSGFSN
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. Plays a crucial role in maintaining the genomic stability by controlling the degradation of multiple proteins involved in mitotic progression and DNA damage. Regulates epithelial homeostasis by mediating degradation of CDKN1A and isoform 2 of TP63. Plays a regulatory role in innate immunity by negatively regulating IRF3 activation and IFN-beta production. Mechanistically, inhibits TBK1 phosphorylation and 'Lys-63'-linked polyubiquitination independently of its E3 ligase activity. Alternatively, promotes 'Lys-27' and 'Lys-33'-linked ubiquitination of IFIH1/MDA5, promoting selective autophagic degradation of IFIH1/MDA5 to inhibit antiviral response.
Subcellular Localization:
Cytoplasm. Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MPSRKCRACASCISKRAARSAPAARGWRAAPHAPGAPAGGRRAAGGPAPPPARLPPLLPSPPPLPSPPPPPSPPPRPPGRSPAERRAPSPGRGAGRASPGRAAWRRGARGSLPGSPAAPGGPRLPCQRSRKLKNAEDRWMGSIGRLHYLTMTTENPMPGDLAPAPLVTCKLCLCEQSLDKMTTLQECRCIFCTACLKQYLQLAIREGCGAPIACPDTVCLNHGTLQEAEIACLVPMDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVQVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHGALFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKTHDPSTT
The following text describes a protein:
Function:
Involved in the degradation of 4-sulfocatechol which is a central intermediate in the degradation of substituted sulfonated benzenes. Catalyzes the hydrolytical desulfonation of 4-sulfomuconolactone to yield maleylacetate.
Sequence:
MLPADQAGIPPCQGPRARSAPISFAIPKGAWDTHLHVFGPTAVFPYAEKRPYTPPDSPLEDYLALMERLGIERGVCVHPNVHGIDNSVTIDAVERSDRRLLGIIKPHRVMTFTELRDLKTRGVRGVRFAFNPQHGSGALDTELFERMHGWCRELDWCINMHFAPDALEGLCDLIAGAETPIIIDHFGRVETAAGVNQLPFKILRDLATLDHVWIKLTGADRISHSGVPYDDVVPFAHALSEIAPDRLLWGSDWPHSGYFDPKRMPDDGDLLNLVARFAPDVALRHKILVDNPARLFGVI
The following text describes a protein:
Function:
Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules. Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore.
Sequence:
MSKESVRESKAATEYRLSISSNPGSRRSSFGGSSEHPAGSGIGNNKASNGELREATLVDTLLLPQVQELKDSMITLDANLTHMNFIHESLVDLNESVSALLYGLMCNSWCVDFPNMPHHTARELGISKELARLKEEKQQLLADLQGTAQAPSLVLKEKEPNTSKQKFQLPKPPMVSTRSVVAPVRTISEEEEDDNTAASFVSNPTVMGQPPHAPPPVARSNNAKGRRRYSILQQIRNHDLTGQKHMVANLGGTVKARAATHPIPESAGEKRKSLAVSAVRIGNNKRLQTSRPPSGGRDVTMARKRSGTQPAILNTNSITHSSTGAVPASSAQGRRPPFR
The following text describes a protein:
Function:
May act as a transcriptional regulator. May play a role in neurogenesis and neuroendocrine cell differentiation during embryonic development (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MPRGFLVKRNKKATPVSYRVRSEEDEQGAFVAQDVPCARRPVSPVQFGNPETVYRAMYSPTRPVSREHERACLERRFNLGSPISAESFPAAPNCSDQAPVDLKIGTSNSNRTGTTVTTKRPASDTERKGKPASKKAKAMRKLQFEDEMTTSPVLGLKIKEGPVEQKPRSQCASGDKPLGEFVCQLCREAYADPFSLAQHKCSRIVRIEYRCPECDKLFSCPANLASHRRWHKPKQSAESNKTPAPEKEETSSDRDTPSPGLSESGSEDGLYDCQHCGKKFKRQAYLKKHVTAHHDAPEKPQSHAPLNLSASECHLCPVCGENFPSRMSQERHIRLQHSAQVYPCKYCPAMFYSSPGLTRHINKCHPSENRQVILLQMPVRPAC
The following text describes a protein:
Function:
Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
Sequence:
MEPILVVAATRQELTLLIRSLGARERGGAGRRPSWLGKVGLLPVVLAETGIGKVNTAAALAALFENFIPRLVINTGCAGAYTASGLRVGDLAVASAEISGDEGVLTPQGWEGLDLIGIPALERKGVRYFNEFPLSLHPAEQAVQLATALGIPLRRGKFVTVSTCSGITARGDELASRFDAICENMEGAAMAQVALDYGVDCLEVRGVSNMVEDRDLSRWNLPLAVEKAQRFIIKYLETCGEEQ
The following text describes a protein:
Function:
GTPase that may function in mitochondrial ribosome assembly (Probable). Involved in a variety of growth processes during vegetative development and promotes growth and cell division in the developing integuments.
Subcellular Localization:
Mitochondrion.
Domain:
In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern; The DARXP motif is also sometime designated as G6 region.
Sequence:
MVMMLKKTVKKGLIGGMSFAKDAGKINWFPGHMAAATRAIRNRLKLSDLVIEVRDARIPLSSANEDLQSQMSAKRRIIALNKKDLANPNVLNKWTRHFESSKQDCIAINAHSRSSVMKLLDLVELKLKEVIAREPTLLVMVVGVPNVGKSALINSIHQIAAARFPVQERLKRATVGPLPGVTQDIAGFKIAHRPSIYVLDSPGVLVPSIPDIETGLKLALSGSVKDSVVGEERIAQYFLAILNIRGTPLHWKYLVEGINEGPHADCIDKPSYNLKDLRHQRTKQPDSSALHYVGDMISEVQRSLYITLSEFDGDTEDENDLECLIEQQFEVLQKALKIPHKASEARLMVSKKFLTLFRTGRLGPFILDDVPETETDHPNSKRVVVL
The following text describes a protein:
Function:
Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
Subcellular Localization:
Plastid, chloroplast stroma, chloroplast nucleoid.
Sequence:
MILLVNGGAATSIHPNAARFYRIGTMSRQIHGAVSSSKHISLKTQHPLSDSNSELAYGASGSETRVYTRKKRLKQEPFEPLEKYSGKGVNTHKLCGLPDIEDFAYKKTIGSPSSSRSTETSITVTSVKTAGYPPENWVEVLEGIRQMRSSEDAPVDSMGCDKAGSFLPPTERRFAVLLGALLSSQTKDQVNNAAIHRLHQNGLLTPEAVDKADESTIKELIYPVGFYTRKATYMKKIARICLVKYDGDIPSSLDDLLSLPGIGPKMAHLILHIAWNDVQGICVDTHVHRICNRLGWVSRPGTKQKTTSPEETRVALQQWLPKEEWVAINPLLVGFGQMICTPIRPRCEACSVSKLCPAAFKETSSPSSKLKKSNRSKEP
The following text describes a protein:
Function:
The major functional amyloid subunit in this bacterium. Upon overexpression of the endogenous six-gene locus (fapA-fapF), cells form large clumps during liquid growth, make large amounts of biofilm and produce amyloid fibrils.
Subcellular Localization:
Fimbrium. Secreted. Note=Part of an extracellular amyloid fibril.
Sequence:
MKATMVLTPLALAMAAVLSVSAYAGNEGGWHPPKPNPQSNNKGGATALVVDTQQNYNNKVSNFGTLNNASVSGSIKDASGNVGVNVAAGDNNQQANAAALASADASFVFGTATASTSVLQSGYGNTLNNYSNPNTASLSNSANNVSGNLGVNVAAGNFNQQKNDLAAAVSNGQYSTAGSAASQTSTGNTTVNSANYAYGGTYVSLKLNADGSYKGTSDQIGDVYLDTWEGQTHPGGSNTGHIDVDSQAQGAKDLNHDGGAFAFKEKGDVDLKGTVSGFIPAIVGFKTPVTNNASLSNSLQNVSGNVGVNIAAGGGNQQSNSLSIAAGCSSCPAGGESLGF
The following text describes a protein:
Function:
Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTATQLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIPERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLVTIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPAKELVGHQLALPRLHQDDEIGMLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHAITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGKNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQQPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDFGMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLAQSLNLQMIAEGVETEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK
The following text describes a protein:
Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MKTMENFWTLTRHNLEIPCILSEHSHKTEGFKFGSSLWCDYKARFILDISHIIQGLTAMKIQQAQTYKGIRWQVTFAIFLSCLCVSVCGQLQYSNFEEMQKSSSVGNLANDLGLNIKEISVRKLRIISRSSEKYFSVNLENGNLYVADRIDRETLCGTTEECFLTFDAVIENPLNVFHVRIDIKDINDNPPRFAHEIIELEMSEYTLPGALFALEKAEDLDVGKNSLKDYKLSENKYFVLSESTSTDSSTIPKLLLETTLDRETESIHELVLTAFDGGNPGKTGTALIRIIVTDFNDNLPVFTQEVYKVSINENIPINSTILYVSANDKDEGINSQITYYFSSSSKQIKNAFIINSINGAIVTKENLDFEKAKQYEISVQARDGGGLVSHAKVLIQILDENDNAPEISVTSITTPVSEDSPSGTVIALIEAHDLDSGENGEVDCQIIGSVPFKLLSSSGNFYKIVTTSNLDREKSPHYSIIIEATDKGFPPLTFRKTIRLDVSDINDNPPVFKNSNYLAYISENNQPGASIYSIQAIDNDSEENAKLIYSIITMNTEEPSISSYISINPVTGVIYAQRSFDYEQDREFQIQIMAKDNGYPPLNRSTIVTIRVTDQNDNSPLVLYPSADVGGSASYEMVPFSSEQGSLVTKVVAVDADSGHNAWLSYHFLQDSEISHFMIDRHTGEIRTSRVFQERDVLRHKVVVIVKDNGTPSLSASVTLTLVVADNFQHVLPEISNQPMKSDSHSNMQLYLVIAIALISFLFMLSVVIAIISKYRESKSPTSFCSLSTYPQTDHRFLTQFNNGTLPLPYSYDVCVTLDSSERDFAFLKPHSNVPVESLIDADDSGIGNEKDIAPVAGIVQQAQPNADWRISQAQRPGPSGAQPAEESGVWPNNQFETERLQAMILASANEAAEGSSALGGGTGTMGLSARYGPQFTLQHLPDYRQNIYIPGTTATLTNAAGKGKSAAPSGGNKKKSGKKEKK
The following text describes a protein:
Function:
Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.
Subcellular Localization:
Cytoplasm.
Sequence:
MTAQTTAMEALQKELDRLNRAPGLSATEDRVDNIIEMLTSVKDQIVQSGMDTHVASMSITKIQNPIKSSFEKINDDLKGVTATQRKLGKTLDKHFPLKDLPSTHDAMADQESLINRAISMHLLREGQFSVASTFIEETGDAATLENANAVVEGQDQVSASDNYDDEPMDEDRDDDDDDDDDEDDDDDEYMSPLEGAATGLGFRQLQNLSSLQSHELEAKFSQMYTILQDIKSRNLLSAIEWARSNSGELEARGSNLEFELSRLQYVWLFKGPRVNGLPDNELNGTAGALLYAQQNFWRFGNRYIGEIQQLANAQIYARNLSESPYRHTFSTETAFADVASSFTREFCSLLGLSAESPLYVAVTAGALALPLLMKYQQATRAKGTEWTTTNELAFETPLPERMLYHSIFVCPVSKEQTTEQNPPMMIPCGHVLAKETLQRLLKGTRFKCPYCPAEGLEKDARRIMI