lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May play a role as marker for the diagnosis of metastatic breast cancer.
Subcellular Localization:
Secreted. Membrane.
Sequence:
MKFLAVLVLLGVSIFLVSAQNPTTAAPADTYPATGPADDEAPDAETTAAATTATTAAPTTATTAASTTARKDIPVLPKWVGDLPNGRVCP
The following text describes a protein:
Function:
May be a cell surface adhesion protein.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MAALLLLALLLLSGAAAIREDKGPQHLLEFRGIDSPRHGRHASDKPPMTPQATTLTLTGLLSTSGCGRFAALVAATPNASEVLEQRFAANAGLTVFCPDDEAVTAFTPTFHNNLSAGCQAALLLHHAVGARGARGRVAATANGTVLPTLAATAIVFLNPRPPGAAVVRKTALDEARLGLAVHVLDAVIALPIAGEDRCVCGGFKVNWLGRLYCFPSWAVPFWAVLSGAVTGCLLVSR
The following text describes a protein:
Function:
Plays a major role in single RNA editing events in chloroplasts. Acts as a site-recognition transacting factor involved in the edition of the site 1 of ndhD (ndhD-1 site corresponding to cytidine-2), which is a plastid-encoded subunit of the NADH-plastoquinone oxidoreductase. The interaction with CRR4 is required for its function in editing the ndhD-1 site.
Miscellaneous:
MISCELLANEOUS: Unlike other RNA editing factors, DYW1 does not contain identifiable PPR repeats but does contain E(+) and DYW motifs. Therefore its association with CCR4, which lacks E(+) and DYW motifs, but does contain PPR repeats, is required for its function in RNA editing.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MALEAAFSMSFCSFSVPKAIFCERETSSFQRITSRAKGIAGESQVQSSDGVETQVKETSPKVFDKLPERNLDTWSGGRETARGLSGSVVRNTVRKDTTLRHISPSSHSTKVRGDKPEISGGEKKAIVDRSKAYVKLKSLGKEVRDAGYVPETKYVLHDIDEEAKEKALMHHSERLAIAFGIINTPPGTTIRVMKNLRICGDCHNFIKILSSIEDREIIVRDNKRFHHFRDGNCSCGDYW
The following text describes a protein:
Function:
Probably plays an important role in neuronal membrane skeleton.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MASRNSSRRSSAADSSRRSSMAELHEAKELEAEMEYKYKALQDEREMVQKKTFTKWVNSHLARVNCRITDLYTDLRDGRMLLKLLEILSGERLPRPTRGKMRIHCLENCDKSLQFLKEQRVHLENMGSHDIVDGNQRLTLGLIWTIILRFQIQDIRVDEEETKETRSAKDALLLWCQMKTAGYNNVNITNFTRSWSDGLAFNALIHKHRPDLIDYDKLQKSNAMHNLNNAFNTAERNLGLAKLLDPEDVNVEYPDEKSIITYVVTYYHYFSQMKDQQVKGKRIGKMVQSAIDNENMIQDYETMASDLLKWIEQTIVILNDRTFANSLQGVQQQLLAFNTYRTVEKPPKFMEKGNLEVLLFTLQSKMRANNQKPYTPKEGKLVSDINKAWERLERSEHEREIALREELMRQEKLEQLARRFDRKAAMRETWLSENQRLVSQMPVTSSEGSRVNLEDNFGFDLPAVEAATKKHEAIETDINAYEERVQAVMHVAEELETENYHDIERINARKDNILRLWAYLLELLKARRARLEASLSLQRIFQEMLYIMDWMDEMKVRLTSEDYGKHLMGVEDLLQKHQLMEADIAVQADRVKAVNDSAAPFARQDDDEYKPADPQIVGERMSHLEASYQELVALAADRRSRLEESRKLWQFFWDMAEEEGWIKEKSAVLASPEIGHDVTSVNLLVNKHKALEREMQARREYIDGVVGSGEELIEQQHFGAGKIRTRINEVNTQWDDLEKLAEIRKKRLHNAVDLYQFFADADDVENWILDTQRLVGSEDVGRDEASVQSLIKKQQAVSEELNNYQTNISQLHDQAKGLGEEDQQLIHDLQDKIAETKGERESPDVENRLATVDQRYKDLLEMAKLRKLRLEDALALHKLFTEADGVEAWIDEKEQMLNTMEFGNDIEELEVVRHRFEGLEQEMNAQASRVAVVNQLGRQLLQNQHPNSNEIMARQNQLNSRWAALRELVDAKKEDLNSAMGIQNFHIECNETISWIRDKAKLISSTEDLGNDLAGVMALQRRLTGMERDLAAIQAKRVVEMVKKELPLIEEKLDALQKEADKLAEEHPEEADAIRQKIAQIQDVWQELRVILKKRDEALGESGNLQRFLQDLDNFQAWLTQTQTAIASEDIPNNLAEAEKLMTQHAAIKEEIDGYEEDYAKMKEMGEKVTNGQTDAQYMFLRQRLGALDEGWEDLHKMWDNRQEMLSQCLNEQLFLRDAKQAEVLLAHQEHFLTKQDAPRRSGMDQNSLEAAESAVKKQEAFMQTMEANDEKINHVCQFANRLVDENHYAADKIKGKADTIQDRRDGNRKLADDNLEKLRDALQLQQFLQECDELGYWINEKLLTAQDALPEGTRNLHSKWQKHQAFMAELAANKDRLDKVHQNGDDLIREKPETADVVNDRLRQLQEQWDELENTTQSKAQKLFDANKAELFAQSCDDVDTWINDIDTQVKSEEYGQDLTSVNILLKRQQLLEKDVDIKRQQMLELQNQAEVLRNEGSIVDEVDGKRVQVEESLASLATSESVKERFSQLEGPLSERRKMLEASKELHQFHRDVEDEKLWVAEKMPQATSRDHGNSLLNVQTLMKKNQSLRAEIDGHQPRIDEICERGQAMVSRSHPSSDAIEHQIEDMQNQWAVLIDEVDARKLRLEDSEKAQQYYTDVAEAEAWMSEQELYMMAEDRAKDEPSANAMLKKHEGIENTIEDYAQTVHELSETSRNLIAENHPESDRIATRQAQIDKLYAGLKHLAEERRGKLDETLQLFLLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQDRFREFARDTGNIGSERVAAANEICDKLIDQGHSDAATIAEWKDGLNEAWADLLELIDTRTQMLAASYELHKFYYDCKEVLGRIQEKQQSMSEELGRDAASVTDLQRKHTTFEADIQAIGSQVVAVQEDANRLKCAYAGDKAKQIEQREAEVLEAWNNLNMGVEGRKVKLGDTLDLHRFFNMQRDLMLWMEGIIRQINTDERPRDVSGVELLMDNHRSVEAEINARDESFAECIQLGNSLIERQHYASKDVEEKLVQLKEERKTMVDAWERRWDFLQIMLEVYQFARDASQAEAWLMSVHGYLNKENLGDSVAEVEKLIKKHEAFEKSTGTQVERFTALERLTTLELREKKKSEEEDFRRTHPESPKAVSPPKSPESHDSDDEATWQASPEPQVVQASFQQHALETDLDSAEVAQHHVSFAEPGSPMWVEVHDTPVDDEHDPSSHLDVSTDIDTDPETNVDIGAREEAQAIVDGEVAEPAKPSPDRQQPVVNGEHEAAQEVAPAEPAVVNDSGEPAQAEPTMEGMLHRKHEWEAHAKKASNRSWSTVYTVLREGMLSFHKDQKAFSSNVTFHGEEPVTVVGGTCEAATNYTKKKNVFRLKLANGGEYLFQAKDEDEMNFWIHKISSIADVGESKEPARAATYPPTRGEAGDSSPQAPERKKRGFFTLKKK
The following text describes a protein:
Function:
Transcriptional regulator that controls expression of some virulence factors in a cell density-dependent manner. Acts as an activator of the gene encoding protein A (spa). Negatively regulates the expression of alpha-hemolysin (hla).
Miscellaneous:
MISCELLANEOUS: Mutational analysis of the spa promoter suggests that SarS might stimulate spa transcription by competing with SarA; MISCELLANEOUS: The regulatory events observed in strain NCTC 8325 are not representative of the events that occur in clinical isolates of S.aureus.
Subcellular Localization:
Cytoplasm.
Sequence:
MKYNNHDKIRDFIIIEAYMFRFKKKVKPEVDMTIKEFILLTYLFHQQENTLPFKKIVSDLCYKQSDLVQHIKVLVKHSYISKVRSKIDERNTYISISEEQREKIAERVTLFDQIIKQFNLADQSESQMIPKDSKEFLNLMMYTMYFKNIIKKHLTLSFVEFTILAIITSQNKNIVLLKDLIETIHHKYPQTVRALNNLKKQGYLIKERSTEDERKILIHMDDAQQDHAEQLLAQVNQLLADKDHLHLVFE
The following text describes a protein:
Function:
Component of the 19S cap proteasome complex which acts as a regulatory subunit of the 26S proteasome, involved in the ATP-dependent degradation of ubiquitinated proteins.
Sequence:
MSDEESNYVEPAVNKVPNYEVSEHAFLLTQPKLHNRHPESLEFVMKAIREEKMAPYYKYLCEEYLPSGLIEWDQALYDSLVDANTQDITELKEHLQEIEEKDEGELEKAQCWIKLGEYYAQIGDRKNAEETLTEAINKAVSMGAKIDIMLTITRLGFFYNDQVFVKQKLAQINSMIEKGGDWERRNRYKTYKGIHCLAVRDFKEAALLLVDSLATFTCVELTSYENIATYASVAGLYALERVDLKAKVIDSPELLSLMSTTPALQSITSLTISLYTSEYSSYFPYLLETYDNVLMPCKYLNRHADCFVREMRRKVYAQLLESYKTLSIKSMANTFGVSVEFLDKDLSKFIPNKQLNCIIDRVNGIVETNRPDNKNAQYHQLIKQGDGLLTKLQRYGAAVRLTGTDRSV
The following text describes a protein:
Function:
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability. Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1. Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway. Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation.
Subcellular Localization:
Cytoplasm.
Sequence:
MHKNSKRNSNSRVSHTEVNSVDAEKEKNESENNFVELLPQELTFKIFSQLDIRSLCRASLTCRSWNYTIRNSDSLWKPHCMTVRAVCRREIDDDLESGYSWRVILLRNYQKSKVKHEWLSGRYSNICSPISLPEKTMYPMDADTWGEILEAELER
The following text describes a protein:
Function:
May be involved in mitochondrial translation initiation.
Subcellular Localization:
Mitochondrion.
Sequence:
MNSYLQFPHRKLFIQFSYSLTSVFRKCQSRTFMNSQFASAKLSNSIKKYFDGRIDESIKYQEIFIRGLENKGKLSKTSLVEALARVRAKPETVLYKVADPNENNKYPICSIISYTELSKLRENQSSRLREAEKSKHKNKTRTRYVLFSWRTDVNDIERKLKSVKDFLQDGNIVEIHVQNKKRSQPVSQEVRDSILSKIQLEIEGLGKDMKPPIVNSHSATFLLQPLVSKSSEL
The following text describes a protein:
Function:
Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAGCAARVPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLSFSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSAAGLLMVIFGECLRKVAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVGL
The following text describes a protein:
Function:
Required for nuclear migration.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Localizes to the plus ends of microtubules.
Sequence:
MSEHGADLRFDSPEKEIKHWKSKVADMQDALRETESSLQDFVESSKELEQEMEKELSASNKTISDLKRRNEQLSGDLEDWKSKYSRALSEHNATLTTLQKELGQLRESVDIYKAKLRDTELTNDELENAERMVASSLADMEGKYNKTIEKTALLEEELIEKTRLDEENQRLKDELREMTEEMTILRDLVTRSRAISRADTMASSTYDDSTAPRSEQSFDSSPIKPSSAARATERPSSRQALSSPVTNRVPISRRLGAMGHNRRLSRDVRAAEAPSLAAVLDDSPTATTTSAAPTRSSTLSRRDPLAATPYHHGASTSHGLTSSPSARAQLRASVRAAARIGGAVSVSSAPRSTNLSANGGAAGSKRMMAEMISKMKALESRINSAKDLSRVVGPGDESAIPRPSSRMATIGSPSANGHNSIHMPTSTPRAPRASMDGNRTIGSSIPVPSRVRRPSSRMSERGTPPMPSLGLPRAQTPSSLHARGSSRADGPSPLPLHEFMDHDPASTLPHAARYAAAQASVAKRRTSMSGSGMSHSASHGSLAKVRSGSTLPRSTTPSTVAAPRVTQSSMTYYGAEASMSKRTPLSTRLASSHRNASSARGSINGPPSSWKTSAMPAQTLSRSRSSSLGSETETF
The following text describes a protein:
Function:
Sphingomyelin phosphodiesterase (sphingomyelinase) that converts sphingomyelin to ceramide (N-acyl-sphingoid base) and phosphocholine at acidic pH. Displays its enzymatic activity when secreted. May play distinct roles in signaling.
Miscellaneous:
MISCELLANEOUS: There are two types of sphingomyelinases: asm (acid), and nsm (neutral). Only acid sphingomyelinases have been found in worms; MISCELLANEOUS: Does not require zinc ions as a cofactor.
Subcellular Localization:
Secreted.
Sequence:
MRIIYLISTVLLIYTNATVLRTKESIQNKVTYDKYGFQPLCISCTGLISVASFFLKFDVSEPVILEFATIVCKLFAKQPWAVCDGISSQFRDEFFYVFRRLANESPSQICGIILPDCADPTDPSESGWMVALPPKPKRTRISKKKVQKKPNMSMSQNLNVLQLTDLHVDFEYKYPSEANCDDPVCCRVSVSEPKKAAGYWGSVGKCDIPFWTVENMLSHINKTHMIDMVIMTGDYINHVDWEYSIEEHLSVLRKLHRLVQNTFPSTPIYWALGNHEGVPVNSFAPHSVDERFWPTWLYKEFQTMSGPWLSEGAKDSLLKRGSYSTQVMDGLKLITLNTGFCEVTNFFLYLNQSDPDSSMSWFVKELFESEKKGEQVYVLAHIPPGDSECLEGWAFNYYRVIQRFSSTIAAQFFGHDHLDYFTVFYEDMHNVSSKPISVGYASPSVTTFEYQNPAYRIYEIDPYNKFKIVDFTTYYADLEKATEDKKPVWEKLYSARQAHGMDDLSPLSWNKVIQKLFTSEKKREKFYQYAFRNFSPQCDSTCQMQLMCNLRMGHHNSTLYCPTF
The following text describes a protein:
Function:
May play a role in mesoderm and/or neural patterning during gastrulation.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
Sequence:
MFWRKHVRILFTVTLIWQAIHLGKGREKEHEKDVKNFNDTAQKQSPKNSVTIIDAFSDMNQSYQSRKQQNSREFVPFTGITESKNLNRNCCQNGGTCILGAFCACPKHFSGRHCELRKCGSIIHGDWVMKGCWLCRCLYGTLKCLSQNTQDGCELRREEEIIRLYSNGLRLQQTMSALICLLTFLLELCCWQL
The following text describes a protein:
Function:
Putative phospholipase.
Sequence:
MFFVFLSGSLCVQRMISAYYHAETGEYMYKEGKYDSDAAARGIFDDTDFNSTGWYNLQIEGKRGTDALAETHAAGYIEGIFTASFYKNHRNNVYQHLCSKYIKCEDNYTIPKVIRDYFKNNYNWVKLTGLSNPDMSDPWYFAAATTMAQIEGMVEAYNKVSNDDTLTIEDLWMFMSHASIYDIARAQGFALQQDNAPLFTRRGTVIVGRTSSLDNVFIGQTAWRTYGESVRIAKRYRLRYNSTGNIVDRRSLSSYPFMLHSDDEFCISDMGLAITSTSIITTNDYAKTVQASFQGYPYWFRNIVATLASHSAGEWFDNYKSEYSTGTGIEYILLDIKKFKYKEGYQDEFVLAVDEIPGQNAESKDMTSRLIEKRFVGSYDVPAVESIFKTAGYDTLAQTSPEWYSYENSARAKILQRTCQSIYDDDKMKTLIRLNDKDRYSEQGDTTTNAIAGRFELIKPASDAMCFGAFDAKFTSIPRMLHSEWVGQVGASYDNLPQLNLLNADACDNSDYVGVDTQMYNGWVDQYFDIEID
The following text describes a protein:
Function:
Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).
Subcellular Localization:
Cytoplasm. Mitochondrion intermembrane space.
Sequence:
MSSLSAASVEPPALESTEKKPLKPCCACPETKKVRDACIIEKGEENCGHLIEAHKECMRSLGFKV
The following text describes a protein:
Function:
Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MELRRGGVGSQARARRMDGDSRDGGGGCKDAGSEDYENLPTSASLSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLNPDPKAHYTSVYGALKKIIRTEGFWRPLRGLNVMMMGAGPAHAMYFACYENMKRTLNAVFHHQGNSHLANGICKRLSGVRKVSPSTDPSPGFSSL
The following text describes a protein:
Function:
Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane.
Sequence:
MATEIDLLRDQKDKLNDILRQHQIEHIFRDPTMQNSMSKGGRGDTLVDSINEQSSLPPLIAEYEKHLEELNRQLTYYQKHMGEMKLQLETVITENERLHSKLKDAVEKQLEALPFGTGIGNDICADDETVRILQEQLQLANQEKTWALELWQTASQELQSVQKLYQEHMTEAQIHEFENRKQKDQLNNFQQLTKKLHVANENIEMTNHHFLKTVTEQNMEIEKLRKHLRQARLDLRVAVSKVEELTKVTEGLQEQMLKKEEDIMSAQGKEEASDRRVQQLQSSIKQLESRLCVAIEEADVLKTGKSNLEKQIKELQAKCSESENEKYEAISRARDSMQLLEEANIKQNQILLEEKQKEVDREKMKKTMSQLIQDAAIKARKEVESTKKQYEILISQLKEELSTLQMDCDEKQGQIDRAIRGKRAVEEELEKIYREGKQDESDYRKLEEMHQRCLAAERSKDDLQLRLKSAENRIKQLEINSSEEMSRSHEMIQKLQTVLESERENCGFVSEQRLKLQQENEQLQKETEDLRKVALEAQKKAKLKVSTMEHQFSIKEHGFEVQLREMEDSNRNSIVELRHLLAAQQKTANRWKEETKKLTESAEMRISSLKSELSRQKLHTQELLSQLEMANEKVAENEKLILEHQEKANRLQRRLSQAEERAASASQQLSVITVQRRKAASMMNLENI
The following text describes a protein:
Function:
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells.
Subcellular Localization:
Cell membrane. Membrane; Single-pass type I membrane protein. Secreted.
Sequence:
MPQREENMKVLPRLVCFIALLISSLEADKCEEREEPIVLVSSAYEIDVRSCPLNPNESNGTIIWYKNDSETPVSMERDSRIHQYKDKLWFVPAKIEDSGHYYCAVRNSTYCLKVKITARFVQHEPDLCYNAQAIFTQKLPLGEDGLLVCPYLEVFRDENNELPEIQWYKDCQPLLLDNINFIGKTDKLIVANVTEAHKGHYTCHISYTHLGKQYPITRVIGLITLDEIRPTKPLIVSPVNETMEVDLGSQVQLICNVTGMFTDFVYWRWNGSLIDDSDPVLVEEYKPVENPSLKRRHTLITVLNISAVESRFYLYPFTCLAKNSYGRSAAYVQLRQPVPDFQKHVIGIFVLLTVAITCSVFIYKLFKVDLVLWYRDSCYDFRPPKASDGKTYDAYILYPKTLGEGSTSNSDIFVFKVLPEVLEKQCGYKLFIYGRDDYVGEDIVEVTNENIKKSRRLIIILVRETSGLSWLGSSSEEQIAMYNALVQDGIKIILLELEKIQDYEKMPESIKFIKRKHGALRWSGDSRKGPQSAKTRFWKNVRYRMPVQRQLPSSKCQLLSPATRPDSKEKLQGEVHVPLG
The following text describes a protein:
Function:
Actin maturation protease that specifically mediates the cleavage of immature acetylated N-terminal actin, thereby contributing to actin maturation (By similarity). Cleaves N-terminal acetylated methionine of immature cytoplasmic beta- and gamma-actin after translation (By similarity). Cleaves N-terminal acetylated cysteine of muscle alpha-actin after canonical removal of N-terminal methionine (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MPHTNEDPTAQQAGVILDPPPPLPPPPQIHLLPPTVAKCKFFKKVAENSDPSTGGCEELKKMIKNRQSRFNGELKWLLYNQYVPSLIQEGPQCGLVALWMAGKLLNLAHEAPLQTIVEAAVSRGYTAQGEMFSAANMAVLAKEVFGCRSELLTGGMDGENKGKILQQLTSGLPVLIPYDEDFNHEPCQREGHRAHWAVISGVLFGVRCGSFSPDPDIPGLCYPSSDSPSLEDLNIQEIYLVAKQGKSLRYQLWEYDCISRSNGQLIHLDPKRSNDGNVYIVPSGGVKAGLCGQIVLFQPKDV
The following text describes a protein:
Function:
Acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Acts by binding to angiotensin receptors AGTR1 and AGTR2. Also binds the DEAR/FBXW7-AS1 receptor; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis; Is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets; Stimulates aldosterone release.
Subcellular Localization:
Secreted.
Sequence:
MWKRAPQSEMAPAGVSLRATILCLVAWAGLAAGDRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAIFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLALYTPVVLPRSLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYVHFQGKMKGFSLLAEPQEFWVDNSTSVSVPMLSGMGTFQHWSDVQDNFSVTQVPFTESACLLLIQPHYASDLDKVEGLTFQQNSLNWMKKLSPRAIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEADEREPTESTQQLNKPEVLEVTLNRPFLFAVYDQSATALHFLGRVANPLSTA
The following text describes a protein:
Function:
Putative phospholipase.
Sequence:
FCSPSSSTLYCNNLRYYLTRNTQHMLKKIKRNPNSAYWNQIHLLLVQAQGLIDGYYKRTHINANIRFKPFGLYYLNLLGDMETLQPIMKVVTSPDDVKPGSCSALVKLLPNNTDVFMGHATWTNYRSMLRMMKRYNLNFKDKSDTGNKIPGHTMAFPSQPGQLYSKNDFYTLSSGLVTMETSMSNFNKKLWTIVREQYWNVLEWIRNVVANRMAGDGEEWCEVFSRHNSGTYNNQWMIMDYNKFEPGVQPTKDSGLLYLLEQMPTLVTYRDITEHLVNQTYWPSYNLPYFKETNKLSQLYRISNIYKSFSYHGATRAKIFARNQTRVKDIKTMFKLMRYNNYKHDPLSACNCDPPYTAAKAIAARGDLNPANGTYSLKSYGLADYVATDAKVVGYSMMKNFEILAECGPTHDQQPPFVWSKSPFSHVSHKGMPDKYDFKPTLIIWDKFSPLKMLDKIHKSVNL
The following text describes a protein:
Function:
Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.
Subcellular Localization:
Nucleus.
Sequence:
MGRRKSKRKPPPKRKNIEPLDQQFNCPFCNHEKSCEVKMDKSRNTAKITCRVCLEDFQTGINFLSEPIDVYNDWVDACETAN
The following text describes a protein:
Function:
Transcriptional activator involved in the FRIGIDA-mediated vernalization pathway, but not in the autonomous flowering pathway. Acts cooperatively with FRI (FRIGIDA) or FRL1 (FRIGIDA-LIKE 1) to promote FLC (FLOWERING LOCUS C) expression. Required for the stabilization of the FRI-C complex.
Subcellular Localization:
Nucleus.
Domain:
The zinc-finger motif is essential for transcription activation.
Sequence:
MSDSDMDIDDDEVEQKVQVHTIVRESELFDKPPIQASNSHNDVKRHSVTTPLDEQSKIIKEQAFAQDNGTLPRFPAPGIPPRSFFTGGGGNEPEQKRAALPCKFFAKGWCFNGVSCKFLHVKENSNCTSQQLAENSMAGNGGIRSDLERRILDSREGVRVSQLSENGVTSLPTREDISFMNPQRVFSSMSFVNPPGSQRVFPFNNEMRFMPSFENIRRESLKQTYGADFTDNRSLVINNANSFALRSSFVHEHRPSISSYLKTDMGSAGPAWTGSLSSSVPMNDRASTVGDFENGNSLSGSGSLPTLQGVAVSSDKGAEANTTSTKKKVSSDDWEPSEPFKASFTIPPYILPSSDALYDPFTDIENLGDRPLNDSLSSKGEHARKSSCQQKDGDSASGPQARDCKNDDKSSSCSQNQHQETVARSLEAHGVVEGVATSVVDQNDTATPSKEISSATAAENRVVLKRIKPAGHDSWHRSDGSSYKKTKKSDEIDGEVRSDAGMKVMRLFRTAVVETIKEMLKPLWREGRLTKDVHNMIVKKAAEKVVGAAVQFHQVPTDTESVDQYLGLSGTRIVKLVEGYVEKYGKP
The following text describes a protein:
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Localization:
Synaptic cell membrane; Multi-pass membrane protein.
Sequence:
MTTTPKIKAPVSGPGLPLLLQMLMGMLLMGLTSVPGATATADPKNANVKALDRLHAGLFTNYDSDVQPVFQGTPTNVSLEMVVTYIDIDELNGKLTTHCWLNLRWRDEERVWQPSQYDNITQITLKSSEVWTPQITLFNGDEGGLMAETQVTLSHDGHFRWMPPAVYTAYCELNMLNWPHDKQSCKLKIGSWGLKVVLPENGTARGESLDHDDLVQSPEWEIVDSRAHFVSQDYYGYMEYTLTAQRRSSMYTAVIYTPASCIVILALSAFWLPPHMGGEKIMINGLLIIVIAAFLMYFAQLLPVLSNNTPLVVIFYSTSLLYLSVSTIVEVLVLYLATGKHKRRLPEALRKLLHGHLGTWLLLSVFSTTGESQAEKTKEMDEHPYEEADEQESSPLGINHTEVPGAKANQFDWALLATAVDRISFVSFSLAFLILAIRCSV
The following text describes a protein:
Function:
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
Sequence:
MEIKFVSKEIDNSFRCKKSYNNTEAPCDLCKAPVLNSDKKSHEENYCPKKKISCQYCNKSLKREKKEKHLASKCPKVKEKCIFNGCNVEKTREEMKLHKESFSEHISLINEMSNSLEETKKKQESHSEQINSLYRKSDFLEKMLKNNQFEMEKFINRFSPLEEKPVCNLTILNSFNKS
The following text describes a protein:
Function:
Possesses tyrosine phosphatase activity.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MRRLLEPCWWILFLKITSSVLHYVVCFPALTEGYVGTLQESRQGSSVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGSHQSPIDILDHHARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQALNDRVVSKSAVRDAWNHDLADFLDNPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKATISHISPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFGGGGISSFPSTVWPTRLPTASAASKQAGRPVLATTEALASPGPDGDSAPTKDGEGAEEGEKEEKSESEDGEREQEEEEKDSEKKEKSEATHTAAESDQTAPAPTPSSPHRTAQEGGHQTIPGHRQDHSAPVTDQPGHVDPGLDTLVDTATQVPPTATEEHYSGSDPKRPEMPSKKPISRGDRFSEDSKFITVNPAEKNTSGMISRPSPGRMEWIIPLIVVSALTFVCLVLLIAVLVYWRGCNKIKSKGFPRRSREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPDDMEAIPVKQFGKSQHGFSGDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIIMITNLVEKGRRKCDQYWPTENTEEYGNIIVTLKSTEVHACYTVRRFSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPDMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSSQLHSYVNSILIPGVGGKTRLEKQFKLITQCNAKYVECFSAQKECNKEKNRNSSVVPAERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQAPISSTFELINVIKEEALARDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLVSTKENGNGPMTGDKNGAVLTAEESDPAESMESLV
The following text describes a protein:
Function:
Transcription factor acting as a central regulator of arbuscular mycorrhiza (AM)-related genes involved at later stages of symbiosis (e.g. VAPYRIN, PT4, PT5, STR, STR2, RAM2, SBT and BCP) but not required for early genes of AM (e.g. common symbiosis signaling genes). Required for the morphogenesis of arbuscules upon symbiosis with AM fungi (e.g. Rhizophagus irregularis, Simiglomus hoi and Acaulospora scrobiculata). Also involved in restricting mycorrhizal colonization of the root meristem.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MGSLNNEVGSIKCEVGSLKSENSFTKLPSEESLASESKKVTPVSSDFELNCGSLAPTSLSFPAMKFEDDIEIQSPDNSIWESFFADHLEGDFMISSPVRNLPSPQPASSFSSSHNNGNNNNNNYNIYAHRQGIHGQDMMMCSPPRSPLGLYNHPSHKGKGLSPLQKVFNSPNNQFMQIESFNLPALESFLDDDYDKEEDLASSYSTLKVSGTGVAGSSSESFDALSVVPDDLLECLALPSSLSNTSGGFMESLLSDTSAVQVINPDDEIFRTGSIAPLSQQLHQERQQEKQQKQRPVTHARPQQQQIINHNVLVPLAAAPDQEQDSGLQLVHLLLACAEAVSKEDYMLARRYLHHLNRVVTPLGDSMQRVASCFTEALSARLAATLATKPSTSALKPFNPFPPNSLEILKIYQILYQACPYVKFAHFTANQAIFEAFEAEERVHIIDLDILQGYQWPAFMQALAARPGGAPFLRITGVGPSPEAVRETGRCLTELAHSLHVPFEFHPVGEQLEDLKPHMFNRRVGEALAVNSVNRLHRVPVNCIGNLLAMIRDQAPNIVTIVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPADSSQRAKLEQYIFAPEIMNIVSCEGPERVVRHERLEKWRRLMEGKGFKGVALSANAVTQSKILLGLYSCDGYKLTEDDGCLLLGWQDRAILAASAWRC
The following text describes a protein:
Function:
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MFKQLRPALASLLVLSLVTGVAYPLLVTGIAQLAFPEQANGSLLRDAEGKVLGSRLIAQKFDGEEWFHSRPSAGDYATVSSAASNLAPSNPALAERIARDAAQERIADQGPVPLALVTTSGSGLDPQLPPQAARYQALRVATARGLPLRLVEDLVESHTERPLVGPAVVNVLALNMALAGLKR
The following text describes a protein:
Function:
Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
Sequence:
MTRPPDLLADVLDGIDALLVFSPSGSYYDRVDDVEGVDVVVVATENAVGAETFVELPLAFDDVREQIRFGIEGALSEGVVADGDELGCVAPFLSEEVDMVTRTRANAGTQSSVYELFASTRAEPGVIRDVFDVAIELGRKGQKGKPVGALFVVGDAGKVMTKSRPLSYNPFEKSHVHVGDPIVNVMLKEFSRLDGAFVISDSGKIVSSYRYLEPGAEGTDIPKGLGARHMAAGAITRDTNAVAIVLSESDGLVRAFRNGELVLELDPEDN