lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MFCLASVIWKELNTSSVEWLPDTSDEATGRSISGLRGYPGSPPPRLDAYAILHISKNLPTFKKFEELAYSPIPNTLSLQTMAPNNTGQKGSQLNQLKQSLKKYGLSRVNSKGSFNSNNKNKSSISSKLKDPEFRQKKLAEIHTSQNVFDTKTSKVKFPTSNQLQRQGSNVSKLNQKNKAIKTVGKPSQSATQAHRRREEKLLPEYLNRHKSSQFLDKRFGEGDSTLTPEEKALERFTKERQDRSSRTKKRNVFNLDDEGEGLYDEDDNAPLTHGGLDLNLDDDDDDPAADDRDQPESIFTKRQDTDRANRSDLDSDEEEHPTKKKTKAEVMSEIITKSKTHKYQRQIMKEKDDQLRDNLNDDLNEIRSLLLSSQPPASSSSHKKKYLSLPSQAVEEDEDTEATEDSTGSGVDRALLETLIGSSSRSSSPAESRDDEEDAYDRFVRELAFDARAMPSDRLKTGEEAALEEAERLRQLEMQRLKRMRGEDDDDDEDEEAPSKNKKNRKRKPEADDLEDDFFPLEDTQETQWSLGDGLRPDGAFGAGADAEDESEEETDDSTSFESGSDDDEEADDDPERALEKIQSLISTESGSKNLKASGSSKAELAYTYPCPSSHAEFLSSLSSASVQSSDLPTVVERIRVLHHPSLGEGNKEKLAIFTDVLIDHLIYISSQPLPPGTSFSDATNGLLPHIISLCKSYTQTAASHFVSKLVLMQKNLTHALTHPNISGWPGASELILFRVIGLLWSTSDFSHPVAAPALLLMNQYLHQLRVKEFADLMSGLFLCTLILQYETHSKRFVPEVINFLVLAVLRMTQTNQTISQIKCLIPILEGSQLTFFPIHQKKMGNMEPQTLDFTGLFGKTASEEAREPSDQDLVDAFDVIISLLNNFSDLYGSLNLYPEVFSSVLVVLESIDLRNITEETKTRITELIGSIRTKIETLNRIRSLNPIKLQSHKPIPIKSQTPQFDSQFNPNQRKFNPDSNQVEVDKLKNLIKKEKKGAIRELRKDNRFLAAAQAKEKDLADAQYKTKIARITASLQEERSEEKKLDRLKIRLKKADKAKRGK
The following text describes a protein:
Function:
Recruited by UPF3 associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA (By similarity). Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Required for plant development and adaptation to environmental stresses, including plant defense and response to wounding.
Subcellular Localization:
Nucleus, nucleolus. Cytoplasm. Cytoplasm, perinuclear region.
Sequence:
MDHPEDESHSEKQDDEEALARLEEIKKSIEAKLTLRQNNLNPERPDSAYLRTLDSSIKRNTAVIKKLKQINEEQREGLMDDLRGVNLSKFVSEAVTAICEAKLKSSDIQAAVQICSLLHQRYKEFSASLTQGLLKVFFPGKSAEDLEADKNSKAMKKRSTLKLLLELYYVGVIEDSNIFINIIKDLTSVEQLKDRDTTQTNLTLLTSFARQGRIFLGLPISGQDEDFFKGLDVTADQKKSFKKAFNTYYDALADLLQSEHKLLLQMEKENAKLVNAKGELSEDSASSYEKLRKSYDHLYRNISSLAEALDMQPPVMPEDGTTRLTAGDEASPSGTVKDTSVPEPIWDDEDTKTFYECLPDLRAFVPAVLLGEAEPKSNEQSAKAKEKLSESSSEVVENQQTTEDTTEVSADSASMDDRSNAEQPKEKEEVEKEKAKDTKKEKGKEKDSEKKMEHEKEKGKSLDVANFERLLQRLPGCVSRDLIDQLTVEYCYLNSKTNRKKLVKALFNVPRTSLELLAYYSRMVATLASCMKDIPSMLVQMLEDEFNSLVHKKDQMNIETKIRNIRFIGELCKFKIVPAGLVFSCLKACLDEFTHHNIDVACNLLETCGRFLYRSPETTLRMTNMLDILMRLKNVKNLDPRQSTLVENAYYLCKPPERSARISKVRPPLHQYVRKLLFSDLDKDSIANVLKQLRKLPWSECEQYILKCFMKVHKGKYGQIHLIASLTSGLSRHHDEFVVAVVDEVLEEIRVGLELNEYGAQQKRLAHMRFLGELYNYEHVDSSVIFETLYLTLLYGHDTSEQEVLDPPEDFFRVRMVIILLETCGHYFDRGSSKKRLDQFLIHFQRYILSKGHLPLDIEFDLQDLFANLRPNMTRYSTIDEVNAAILQLEEREHASSGDKVSIERHSDTKPSNKSSSDVISSNGKSTAKDIRENGEAHGEESDSDSGSGSVVRDGQNEELDDGNHERGSESGDGDDYDDGDGPGSDDDKFRVRQKVVTVDLEEQADFDQELKALLQESMEQRKLELRGRPALNMTIPMSVFEGSGKDHHHFGRVVGENGEEVLDEENGEQREVQVKVLVKRGNKQQTRQMLIPSDCALVQSTKQKEAAELEEKQDIKRLVLEYNERDEEEANGLGTQILNWTSGGSRGSTRTGEGSGKSGGSRHRFYYHQGGGGSYHARRK
The following text describes a protein:
Function:
Involved in the activation of the plasma membrane proton-ATPase (PMA1) by glucose.
Sequence:
MRLHYRRRFNFLRRILFILCITSLYLSRDSLKLHAKNVLMDHNVAEYHGGMIDDIQILRCYHWYRQCSSLYAPKLHPSNTAKKIKDKNSILWTRVSKNITVETLYSLQSGPFYNSYLYVHLKDFQSNPKNTIKELAIARDSALIPLQVLRDINKLVKSSDSSVFHNHVYLREKPTSSWWKLLFGISVDTDNIAVFGEEWVYKGSGIWCKYILNDDDNDAPITNLEIYLGSSFIESRPSWKEVIHEFHRNNIPSLPISITRKLETKNHHHKFSNGLLGSLRTPSKDINIQVDADYKITSPHIQFSRGQRSFKILQITDFHFKCTDNSMTVINEIKTVNFIDRVLASENPDLVVITGDLLDSHNTIDYQTCIMKVVQPMISNKIPYAISLGVSDESNLATSAQIRDFIRNLPYTFNNVASEEGHMAIEVSFKKKLTKNTLLERDIDTEDETNPSEALFFVFDSFAPVNNFLQDYNDLIGKIDFGLAFQYFPLSEYRPHGLFPIIGQYNERSTLTVDTPRSRGQVSMTINGKHYKSFLDILSLWNIKGVSCGHEHNNDCCLQSKNEMWLCYGGSAGIGLPRIQGIYPTVRLFNLDDILDEITSWKRNSNLVDEVYDYQYIYKGKQ
The following text describes a protein:
Function:
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro) (By similarity). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro).
Subcellular Localization:
Microsome membrane; Peripheral membrane protein; Lumenal side. Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Sequence:
MWFYLVTLVGLYYLLRWYRERQVVSHLHDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEELKSKTSDRLETVILDVTNTDSISAATQWVKEHVGDKGLWGLVNNAGVFQAFAYIEWCRPEDCMSIFQVNLIGLAQVTLSMLFLVKKARGRIVNVSSVLGRVALFGGFYSCSKYGVEAFSDVLRREIRDFGVKVSIIEPGSFKTRMTDAELIIEKTKKTWEATPEHIRESYGQQFFDDFCNTTRRELKKCSTNLSLVTDCMEHALTSKYPRTRYSAGWDARLFFIPLSYLPTSLVDCLLAISRRKPAQAV
The following text describes a protein:
Function:
Transcription factor that is recruited by AHR1 to the promoters of genes involved in biofilm formation, which include several key adhesion genes. Plays an important role in cell adhesion, hyphal growth and virulence. Implicated in the regulation of opaque-phase-specific gene expression.
Subcellular Localization:
Nucleus.
Sequence:
MAIKEETNEFSQGNEGNSHSTNNNNNSNNSNSNNNADVSAPVDDDDDDDGTSQGKTQKERRKIEIKFIQEKSRRHITFSKRKAGIMKKAYELSVLTGTQVLLLVVSETGLVYTFTTPKLQPLVTKSEGKNLIQACLNAPEEGLGDDQENQSDGNTGDSPDQSPAPATNPNVMGAAGHAHHIQQQQQQQQQAQQQAQQQMAPMPSHGLPTHYSNPQGAGNPGVPPQQQGQHQPGIPLQGGYSDQYSYFGNIQNNNIPNQQQYQ
The following text describes a protein:
Function:
Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MWGPLIYALLGLAIVAAAFLFVRRSQAKEVVPVADDDDKENGAAADEVNPRQAGDQGHTDDEDGEEGNEGLKNFMYDENGKKLGVKKARKLQEKEERRRRNEEMAQAREQAKLLQHQEEEERKEREAEEAEDERQREAELEREREAQRQKELEEYNSLKSMFVVEESGELDVDHEAQAQSLLNEFVSFIKEKKVVQLEDLAAHFGLKTQDTIERIQQLEAEGRLTGLTDDRGKYIFISEEELSEVVKFIERRGRITIAELMDNSNRLISLSETDVEFPGDEPAPADVDETTTA
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Subcellular Localization:
Nucleus.
Sequence:
MDTPQAVAERYADGRLGLTFVRALRRRIAPASGYTEAVRRDRSGEPRMGTDNVPSSSVEAVQRCLQRLCQPIVFYRCDAAAPMSSAAGISPSFTTMPSTRALLVKPHSQSNFYAVDHVTAVHLLQEAVCERVVHSRYGVLGVRIMKLLLQHHFLEERTLAEQSIATYVKVREVLHQMFKDGFLLQQEVPRTSALVERSAKASVYLWGLSWSATLLPVVRERLAKTLTIAWAKLREAQQQASAVAKHAAGGRPTPAAGSSINSSAAHAEEIEAQWKYGMSRNIQQALQAQRAVTGLQSCVMSLMRLLLIVDFFFFKGVRRTVERQTSVGVVGVASLSLSPYRCFGCHARQGDGAVRPARRPSPLFSPSCAPARVVRGA
The following text describes a protein:
Function:
Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.
Subcellular Localization:
Nucleus.
Sequence:
MATAAAAASKPAARTTVNVAGAVFRVQMALLDGAAASDEPLLHAAAGVLSRADYDDVVTERSIADACGHPACASPLPDPANPKAAPRFHISLREHRVYDLEEARKFCSERCLVASAAFAASLPPDRPFGIPPDRLDALVALFEGSGDGPGLLGFRADGGKKGDEGRKVEIVEKETPGPGEVTLQEWIGPSGAIEGYVPRHHPIHEGPMPQAKQGKASRAELSGNKNVDSVAAVLGEHSMAVSSSSVETQVVSEDIAKKFDGMVLHENTKTKEKDANKTLSKIFQQDEDTDMLLPCITDSIAKQLEHVVLEERNDKKKKKSTRASSRASKSKPARKPAGSNGHEVGFTSTIIMGDPASVKMDQGPLGQYDFSSSILTDNQPSSSQYTVRDSMHAYTEQLHKEFSQAGDLEKNGTSDEKVTTALKSSLKAVGSKNRSQSVTWADDNGSILEASKAYDIDSDAKNLSMEDIDSSLRRESAEACAAALIEAAGAISSGTSEVEDAVSKAGIIILPDMLHQKQFENVHGKDTVEKVVSETDSDVVKWPTKTVLLDTDMFEVDDSWHDTPPEGFSLTLSAFATMWTTIFGWISRSSLAYVYMLDDSSVEEMLISNGREYPEKRVSKDSQSSEIKRALASCISNALPVLVSNMRMQIPVSKLETTLGYLIDTMSLVDALPALRSRQWQLLVLMLLDALSVHRLPALAPVISDSKLVQKILNSAQVSREEYDSMVDLILPFGRSA
The following text describes a protein:
Function:
Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm, cytosol.
Sequence:
MMDASRSQQPLDAWDDISDSEFLNIPSDEESIESQLPLIGETKGKHSVNLDKPSSSSSFHKCSEEAPKQEAVKTDDVRGLKRKSLHENSFSPMQRFRKQHLSVTLLCDQTWCEMKSVYNLLKPHIKRKEMQRTEVQIGQEIHLSRELEIQDVVPVDIRTREDGEAVKLLNMLHMIPLLEAGQRVREFPVFGVQEGVFIMGVIDELMYNQKGELVLNELKTRRQNSLPSSAQDKVNCFQVGLYKLLFDGLVRGEMKKNHIFDHLKLRSAQILGAGVQAHAKNLGVHARTFEELVETLLITVSCSDLPCIDLLQIEYFHQGSNGPIGTRVAPFDEAQIRGELQAYLSYWTGQREPKGVDIEEAWKCRSCLYEEICEWRKNRFTVSDQQAAHSSSHL
The following text describes a protein:
Function:
Component of an histone acetyltransferase complex; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in cell cycle progression and meiosis.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MPRDDLSIDFVRKMPPAAELDPALILDEWIHNTQNLPEEIRFMQDEIAEKDRQYDKLVKEIEKNDERIQKFIKANGSFQPNPKEEEYRATIIKNFDLAEQLSKEKLELTRKLQHTFDKHVRALDKQIKSLYDRGEPGFTDPDELPSLVRDSAANITSTPTLLRPVNGNHPISSALNGLANGTGSNAARSNQIRNIQASHHHSASAPATPAATIILNQRARESSAGPGGAVRKGAVRSNSGLSLQTSGIGRHASLGPGTPKSSTTSGGVQRAGSAGPRGIGKGSTSSTSRKSVPSGSSAASRKKGSSVPTAGSGSGSAGGVSASGVSGSGAGGGSSHKSNLSRVLKRAGTGTSGSGAKNSPNTTSRANSTGDSDLSDADSNLSGSESDHRRIGTGRNTPIGGGSHSRSASHHHTNSSFSHKGGADDLNHPHHPSHGHRPSSSLASNGGGGGGTGGGSGGPFQSRNPGGSGGGPLSNPSHPQSISSHNRSRSSTHHQLQEMHRSPSLSSNNRRRNNPGLTDEDDEDVDDDDMDLNVDQEDGMDLDDEEAGDDRKYCLCQNVSFGDMVACDNDECPYEWFHWSCVGLKSEPNGTWYCPVCAKNMERDNTSNSNNNINMNNNNSNNSSSSQGRSDNKKSGSGGSGGGGNSSSQGGGGNNSSQGGGGQ
The following text describes a protein:
Function:
Functions, together with Abl, trio and fra, in a complex signaling network that regulates axon guidance at the CNS midline. Required in part for robo-mediated repulsive axon guidance. May be involved in lamellipodial dynamics.
Subcellular Localization:
Cell projection, lamellipodium. Cytoplasm, cytoskeleton. Note=Expressed at the leading edge of lamellipodia. Colocalizes with chic at the periphery of cells.
Domain:
The EVH2 domain is comprised of 3 regions. Block A is a thymosin-like domain required for G-actin binding. The KLKR motif within this block is essential for the G-actin binding and for actin polymerization. Block B is required for F-actin binding and subcellular location, and Block C for tetramerization.
Sequence:
MAMKKLYAKTSFTSKKPSSAANSTPILAYHQQQHQQPGNGICEFQVVAPGHSGELMIRRSQSMHHKMSPPVGGLGSKSEYYSIEELQELDLLDYRHPMYHHYQQQELRQRYHEHEQLVLQLPKATSPKAGPIYEAPQRSQQQQDQMLYVPTAAQRDSSSSAAATSIASSSTLTSSPSPSSSSSLIFSTLRKCVSPSNPSVNPNQPSKTQPSKLGCSMSFSIRTTTATAATAAAANAATATLSTQQQQQQAQQQHKQHLYSNIHHYLIRQQQQKQHYTLQRRHNSVKDKFIGGITTIFAEQSIIGARASVMVYDDNQKKWVPSGSSSGLSKVQIYHHQQNNTFRVVGRKLQDHEVVINCSILKGLKYNQATATFHQWRDSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGNGYEEDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTSSAPPAPQPQQQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQQPQQQQFQQQQQQQQYQQMVQAGYAPSQQYQQPHYVLSNSNPNLTVHQYPTQQAQQQPPQAPQPPLQNGGMYMVGHGHLPSSASANSVVYASQQQMLPQAHPQAPQAPTMPGPGYGGPPVPPPQQQAENPYGQVPMPPPMNPSQQQQPGQVPLNRMSSQGGPGGPPAPAPPPPPPSFGGAAGGGPPPPAPPQMFNGAPPPPAMGGGPPPAPPAPPAMGGGPPPAPGGPGAPPPPPPPPGLGGAPKKEDPQADLMGSLASQLQQIKLKKNKVTTSAPENSGSSTSSGGSGNYGTIGRSSNGMASMMDEMAKTLARRRAQAEKKDPDPEAEVKKRPWEKSNTLPHKLSGGAGSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPMRKRFGSASEETILKVNGDGLSLALSNGDLDTLKAEIVREMRLEIQKVKNEIIDAIKSEFNRR
The following text describes a protein:
Function:
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSTSKAPEASAPTPDKAELPVAIVCVGMAGSGKTTFMQRLVSHIYTHPDPAQSEPSVSKTASPTPPYIINLDPAVHHVPFTPNIDIRDSVNYKEVMKQFNLGPNGGILTSLNLFSTKIDQVIGLLEKRTQPPPPVKETEQTTVEFMTNSGKEKAAAPAQQQQVKHILVDTPGQIEVFVWSASGEILLSSLASTFPTVIAYIIDTPRTTSTSTFMSNMLYACSILYKTKLPMVLVFNKTDAQDAEFAKKWMTDFEAFQTALRDEEEGGTFGGDGVGGGSGYMGSLLNSMSLVLEEFYKHLSVVGVSAMTGDGVDDFFRSIAAKKEEFQRDYQPELERRRAEREQEKQKSRQRELDKLMKDMKVGGAGTKPKPKSRPNKEEPETVSDVEDQDSDDSMEYRAHEDDEDSDNPDGSLEDRYQQALKNAGAGQDDDMSFARYMQAAKFG
The following text describes a protein:
Function:
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
Subcellular Localization:
Cytoplasm.
Domain:
Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex; The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.
Sequence:
MNQWQLSYQSPVELTEHLRKSYWAYDAKEKSATKMAFDQDVNLIWVGDTYGRVSSYDPSYSLYTRHTAHIGAEPVVELLSHKQGVLSLGGESLNFANRRSVTKLHVTSADIAQLCDMRAMCYGSNSQNTVYCGGTNLASGLVAVDLVKGRLSNTVQYSSKVKLMQSSNRLMAVARQNGMLDLLDPNSNTVVKTFSGHSCMVSSMDFRDHTLVTAGKSKRFNMMYPDQFVNVYDLRIMKQLPPISFSKNTEYMGNGACYMVGADFVQLHPILPTVVVIGSVTGAFDFVDLSNPTVRTQYCHPCQSVTQLQLSPSGDYIAFIEHDNNINMWSRSNGMTGFTSTATTILEYPDYPDDGILAGATSIDDYSYPLSSVGLPYYNEKLLSAWHQTVFRSDGTIPMKVPLPPKSSAASSSHTALSTSSDSRPNTARSGNPSSGGQKYRLLPYDRHKYGHRNVAVPYRSLRERKKKLLITDEDGKDKQELMNYKPSNDREVPPAFTKLQMVYGRFGVQDFDFKAFNKTRYSGLETDIDNVYTNAVLQMYRFVPEVYNFLVSCLKMENFSDNSLLTELGSLYDMMVRANGEICRSSNFQEALASIPKSYLLGLITDSIDNALEPNTTVSGTSISDSDASGSSMTAKLESMVLGDDKTTISCHDNNDNSLTTPQKFNTFLLNRLLFEELQMKINTTQSIVLEELLGIDVQVTTRSISPCANFTRRSDIIPVLTVTSPISNNIKYVNKKLNNQTILPYIESSMSRLKHTKAMCEKCFKCETVESEKTVRNLPPLLSLNISLTSDEWATAKTVRGWLTKEFYATISKDRPILKLQPTDLKTTNAIFKYELNGYVARICDYITEPHLVAYSKIFDPTTRTYKWYMFNDFLVQEVDEEEALNISYWWKTPEIAIYSDAEELTKPFVPASFYTINYSILYRDHFANGMRESIKKEYRLLTAEEAPKPGSLVALDAEFVALSEDQVEISCKGTKTLIKPAKTALARVSVLRGEGDLAGVPFIDDYIVNTKHIEDYLTKYSGIEPGDLDPDTSSKPLVTRRVVLRKIWLLLQLGCIFVGHGLYNDFRNINIHVPKEQTRDTALYYLQGRRYLSLRYLAYALLDKDIQKGNHDSIEDAYTALVLYRKYLDLREKGIFETVLNRIYEEGRASNYRVPGDLQ
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MAEALDASPRSKAGWLARLVKRGAGAAATSSQALPPLEQKASPKGSKKDSVSGVADIRAGSFTSTAGGLADKQAPAKQAAKQQLRSTKSMTSGASGGMLGDCASGSWHSITEFASRKEIGRGRNCIILSAVCTKTKMKVAIKAYDKKQLTPNSQTHIKREATLLKPIKHPSICQFYGAFEDATFIYIVMELCSRGDLMEMLVGEYGVGKLSEERAVQMVMVPLLSALKASHALGVVHRDIKPENLFLDSEGNVKLGDFGLAIDQSKERPKSRIGTLDYMAPEIFLKSWQYEQFGSSDPSAKYDEMVDIWACGVLAYEVTAGEAPFDAAKHGKETRELILYHEVPIKGKAFPPGASKEWLDFIKITLQKKPELRRSAEELLHHPWILKHSKSAAPAAPPPRPLVLDPIASSPPSSQPSSPTAAAASAAASAPTSPSTPSAAHSVSRFAKESVGTTSLNGRSTKPSVLSISIESEDASRDSGGSQPGSPLSSGPSSPLGSPLGSQKARKSALGRVKTANLDMTPKFQPSTPTQINTQRGNSQFSAFDKALEQAEKPWAIDGNDSPVSSLPNSPVTKVRKEPPHWQRSSWNGDKAADE
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MMRIPLLLGITLPLVLAGDYALLFLLPLGPLHWKEIMPACGGDNQSPINIVRRKSQWDKDLDEILFEGYDQAPPGRWRLLNDGHTVVLNLGGAPAAEQINITKGGLHGTYQALQFHFHWGDLNHNGSEHTLDGIQYPMELHIVHINSKYKTISEAKGHPNGLAVLAFLFKVSDADNTNYNTIVAALKNISQADNYVDLASTFPLSNLLPDMPLLSKYYRYKGSLTTPNCDEVVTWTVFEELIPLSKSQLDAFKKMLYFRKMATTSRMTNNFRPIQPLHSRKVYASRDATISSCSRLAPSFVIPLFLYVLVGLFSGPS
The following text describes a protein:
Function:
Efflux system for nickel and cobalt.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MVMIMELLYAITAFILGMLHALEPGHGKSVVAAYILGTKADLKDAILLGTTITISHTAVIFLLGILSIYLLESLNVDVVHDMMSVVGGLILIAVGIWIIRSYLHPHEHKVDTKKGVITLGLSAGLVPCPAALAVLLLSISSGNLIDGLIYVAIFSIGLAISLTGLAVAFVESKELIKKYVGNRKVSKLPLISGSIIILIGLYTIAHPILEHAIV
The following text describes a protein:
Function:
May function in the docking or fusion of transport vesicles with the prevacuolar membrane.
Subcellular Localization:
Prevacuolar compartment membrane; Single-pass type IV membrane protein.
Sequence:
MSFQDLEAGTRSPAPNRFTGGRQQRPSSRGDPSQEVAAGIFRISTAVNSFFRLVNSIGTPKDTLELRDKLQKTRLQISELVKNTSAKLKEASEADLHGSASQIKKIADAKLAKDFQSVLKEFQKAQRLAAEREITYTPVVTKEIPTSYNAPELDTESLRISQQQALLLQSRRQEVVFLDNEITFNEAIIEEREQGIREIEDQIRDVNGMFKDLALMVNHQGNIVDDISSNLDNSHAATTQATVQLRKAAKTQRSNSSLTCLLILIFGIVLLIVIIVVLV
The following text describes a protein:
Function:
Receptor for octopamine (OA) which is a neurotransmitter, neurohormone and neuromodulator in invertebrates. Stimulates intracellular accumulation of cAMP and Ca(2+) following ligand binding. Required for ovulation. Following activation on mature follicle cells by OA, induces activity of the metalloprotease Mmp2 which leads to breakdown of the posterior follicle wall, resulting in ovulation. Ligand binding probably also leads to activation of CamKII which is also required for ovulation. Modulates sleep/wake behavior by acting in neurons of the pars intercerebralis to promote wakefulness. Plays a role in courtship conditioning where the courtship behavior of males rejected by already mated females is inhibited with further females. Required in the mushroom body for appetitive olfactory learning. Specifically conveys the short-term reinforcing effects of sweet taste. In insulin-producing cells of the brain, plays a role in inhibiting transcription of insulin-like peptide Ilp3. Also plays a role in social behavior by modulating male agression.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNETECEDLIKSVKWTEPANLISLAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVLPFSATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAKSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLLNAPPQNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQGFKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYATRRLHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHGVASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCWCPFFTMYIIRPFCQDCVDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRIICRCFCSRQSVSLKSSRRGSDMSAIRIRARTPSITPSAAAHSFGDESELHHSEMSNDPR
The following text describes a protein:
Function:
Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Functions in protein retrieval from the endocytic pathway (By similarity).
Subcellular Localization:
Endosome membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein.
Domain:
The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization to the perivacuolar punctate structures.
Sequence:
MSSVLRNQDNPPTISEVSSTTKENTDNSNSKQEEKEKEKEISSTIENPTFVDDEEDNNPFSHHGEGLTSFMTANSFNEGPNTKSDKRTTKENNNSSSNNNRGDNNDDDDDDSLLLYNTSNNNKSNNVSRVNPMLKSTGEVFKTVNMNFESRVTKLLKPNTKIRIQITEAGNSNEGMSNSSKKYTVYTIKLINLEDPNNDILTRRRYSDFESLRDVLTKIFPLIVIPPIPPKNYFDFSMLNGLVGSNHENSSLSVAGSNGNSGGSGGGGASGGAGSGSGNGSIITSPKTYSYINSTHLTKGKLIEHRKRLLTNFLNNCLEIKQIRSLEFFAKFLDPNANWGDEIALIQSQLPKSIYLSNPENGLKTDPIYSNLPNPSNKNTISFFKDNKKKLTKKTNKLLSNGSENHDIGVGGGGGSIGNGGNGVNGNGTNSQSQYIANTSMLDDINKRIMENYIGLSNDYSKLGSTFNSFSLILAETTTTTTTGVSSATKKSNDNELNLIFDKIGQVFDRSYITINSLIGELETKFSEPLGEIVQYTSIIHYVAKYQSKKIKQKSMLDNEIKDKRKTLEDLLKIERESNRIENAINSQVKPKNGKYNLEQQQSSTVSPAPPPGPPPSSSSSSSSSSKFKFPSFKKITQYVSEIIDQNPEVTRKQKITNLQEKIQILEKCQNIMLADLSFITDEVNKNIQSFQKRQLKMIYKILLLYNKQLIGWAKKNIDIWEEVRDEIAKM
The following text describes a protein:
Function:
Plays a role in the repair and/or biogenesis of the calcium-manganese-oxide cluster on the lumenal face of the thylakoid membrane. Its presence in a photosystem II (PSII) preparation prevents binding of other extrinsic subunits PsbO, PsbU and PsbV, and thus assembly of calcium-manganese-oxide cluster. Psb27-containing complexes lack oxygen evolving activity and an oxidizable calcium-manganese-oxide cluster, but have a normal reaction center.
Subcellular Localization:
Cellular thylakoid membrane; Lipid-anchor; Lumenal side. Note=Associated with PSII on the lumenal side of the thylakoid membrane, its binding site probably overlaps that of PsbO.
Sequence:
MKRFWAMVCALFLSVSLLLTSCANVPTGLTGNFREDTLALISSLREAIALPENDPNKKAAQAEARKKLNDFFALYRRDDSLRSLSSFMTMQTALNSLAGHYSSYPNRPLPEKLKARLEQEFKQVELALDREAKS
The following text describes a protein:
Function:
Acts as a receptor for reticulophagy and nucleophagy. Directs autophagic sequestration of double-membrane vesicles derived from the nuclear envelope and perinuclear endoplasmic reticulum (pnER) into autophagosomes. Is not required for the cytoplasm-to-vacuole targeting pathway, mitophagy, pexophagy, and non-selective autophagy.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass membrane protein.
Sequence:
MSEEDDHWNLVRLRRLRKGREGEEQSSKSEISLDSLHESSFAGEDDEDFDADVLSNTSSEESAQMNRIYDFRTSNEFSNAGVNIDQTGVPTISESFDTLSGSNVGGTVLPSMEGSKLKDSTIRNSSTLSDHIIDKSEGKSAKLKMWHVIMLSSLLSMTFSYLALEYSLTGDVLAGFKSQQSLRNNERKLLYGNIDFVDKKSYDSSSDSLSQWAPSGKYYVDFDNHIAYPLKDDDLMGWRRYKTDLVILWYTTKARMKDGWHKRINKINGGRIKLHLFLKNSFKSAQESLRVLHKEQKRRWKRLFVLLHNKYRQFSPHIKRYFDHSCQKAKQCWSGSRLQLRKLRFKSMKPFRVFQFKVRKDTNWFVKQLKRFGLKLQHSRMYKAMSECRKKNYFKCKH
The following text describes a protein:
Function:
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Dispensable for SPC enzymatic activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDWSSLNIEEKMLHFILPLWAILSMASVYLTSSYRTMVGIYVLGVVIGLIIVVPDWPYFYRSPLSWNEPLGVEIVQPRQSLPNSHR
The following text describes a protein:
Function:
Phosphatase that is active on 2-deoxy-D-glucose 6-phosphate (2-DOG-6P), but not very active on fructose-1-P.
Miscellaneous:
MISCELLANEOUS: Present with 2400 molecules/cell in log phase SD medium.
Sequence:
MPQFSVDLCLFDLDGTIVSTTTAAESAWKKLCRQHGVDPVELFKHSHGARSQEMMKKFFPKLDNTDNKGVLALEKDMADNYLDTVSLIPGAENLLLSLDVDTETQKKLPERKWAIVTSGSPYLAFSWFETILKNVGKPKVFITGFDVKNGKPDPEGYSRARDLLRQDLQLTGKQDLKYVVFEDAPVGIKAGKAMGAITVGITSSYDKSVLFDAGADYVVCDLTQVSVVKNNENGIVIQVNNPLTRD
The following text describes a protein:
Function:
Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA.
Sequence:
MTTMDNTPQGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVKRGTTSISINIEVWVKKVASEPIGQRYKATEALFIYVAVDPDGKPRPLPVQG
The following text describes a protein:
Function:
Involved in the import of activated long-chain fatty acids from the cytosol to the peroxisomal matrix.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MSTTLAAPAKLKSLLLNLHTHCIGLHVNDVTPKVYFKLLIRHLLQISRSNAAHPKLRRRAQILLVSLFLSGVTLFSGVTYSTFKIILKCYKFYKFPWKRRNRRPLIRRTRSQMQLDSGARIMYIPEVELVDRQSPDDNKFMNATDKKKRKRIFIPPKDNDVYEHDKFLFKNVELERAKNSQLFYSKFLNQMNVLSKILIPTVFDKNFLLLTAQIFFLVMRTWLSLFVAKLDGQIVKNIIAGRGRSFLWDLGCWFLIAVPASYTNSAIKLLQRKLSLNFRVNLTRYIHDMYLDKRLTFYKLIFDAKASNSVIKNIDNSITNDVAKFCDATCSVFANIAKPVIDLIFFSVYLRDNLGTVGVAGIFVNYFITGFILRKYTPPLGKLAGERSASDGDYYNYHLNMINNSEEIAFYQGTAVERTKVKELYDVLMEKMLLVDKVKFGYNMLEDYVLKYTWSGLGYVFASIPIVMSTLATGINSEEKNMKEFIVNKRLMLSLADAGSRLMHSIKDISQLTGYTNRIFTLLSVLHRVHSLNFNYGAVPSILSIRTEDASRNSNLLPTTDNSQDAIRGTIQRNFNGIRLENIDVIIPSVRASEGIKLINKLTFQIPLHIDPITSKSNSIQDLSKANDIKLPFLQGSGSSLLILGPNGCGKSSIQRIIAEIWPVYNKNGLLSIPSENNIFFIPQKPYFSRGGTLRDQIIYPMSSDEFFDRGFRDKELVQILVEVKLDYLLKRGVGLTYLDAIADWKDLLSGGEKQRVNFARIMFHKPLYVVLDEATNAISVDMEDYLFNLLKRYRFNFISISQRPTLIKYHEMLLEIGENRDGKWQLQAVGTDEAITSIDNEIEELERKLERVKGWEDERTKLREKLEII