lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group.
Subcellular Localization:
Peroxisome.
Sequence:
MNPNNTGTIEINGKEYNTFTEPPVAMAQERAKTSFPVREMTYFLDGGEKNTLKNEQIMEEIERDPLFNNDNYYDLNKEQIRELTMERVAKLSLFVRDQPEDDIKKRFALIGIADMGTYTRLGVHYGLFFGAVRGTGTAEQFGHWISKGAGDLRKFYGCFSMTELGHGSNLAGLETTAIYDEETDEFIINTPHIAATKWWIGGAAHTATHTVVFARLIVKGKDYGVKTFVVQLRNINDHSLKVGISIGDIGKKMGRDGIDNGWIQFTNVRIPRQNLLMKYTKVDREGNVTQPPLAQLTYGSLITGRVSMASDSHQVGKRFITIALRYACIRRQFSTTPGQPETKIIDYPYHQRRLLPLLAYVYALKMTADEVGALFSRTMLKMDDLKPDDKAGLNEVVSDVKELFSVSAGLKAFSTWACADVIDKTRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNILTLSAGRALIQSAVALRKGEPVGNAVSYLKRYKDLANAKLNGRSLTDPKVLVEAWEVAAGNIINRATDQYEKLIGEGLNADQAFEVLSQQRFQAAKVHTRRHLIAAFFSRIDTEAGEAIKQPLLNLALLFALWSIEEDSGLFLREGFLEPKDIDTVTELVNKYCTTVREEVIGYTDAFNLSDYFINAPIGCYDGDAYRHYFQKVNEQNPARDPRPPYYASTLKPFLFREEEDDDICELDEE
The following text describes a protein:
Function:
Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity). Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity). Also degrades other unstructured peptides (By similarity). May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
Subcellular Localization:
Mitochondrion intermembrane space. Mitochondrion matrix.
Sequence:
MLRFQRFASTYNQRAVLRKYPVGGIIHGFQVRRAVPVPELKLTAVDLIHEQTGAEHLHIDRDDKNNVFSIAFRTLPPDATGVPHILEHTTLCGSEKYPVRDPFFKMLNKSLANFMNAMTGPDYTFFPFATTNARDFVNLRDVYLNSTLRPLLKEQDFYQEGWRLEHSEVTNPKSDIIFKGVVFNEMKGQVSNADYHFWSQFQQNIYPSLNNSGGDPQKITDLHYQDLVDFHHANYHPSNARTFTYGSFPLEDTLKKVNEEFRAYGKRIINKKLPKPLELIETKELTLEGQIDPMLPAEKQTKTSLTWKCGEPTDLYETFLLKILGNLLLDGHDSIMYKGLIESGLGHDFSVNTGVESMTAANFLTVGIQGSQNVEEFKSKVFDLFKEFIENDVDSNKVDAIIHQLELSKKDQKADFGLQILYSILPGWTNGIDPIEGLEFDELIGRLKSDFKENGTKIFKNILDKYIIDQPYFHFTMKGSEEFSSKLAAEESTKLDKKLKELDETDRKAIFERGLLLEAAQNHKEDLSCLPTLGVADISRKVDTYDLNTNANITVRNTATNGISYIRGKKLINDMIPLELYPFLSLFAASLTHLGTKTTPYGAIDNEIKLHTGGISTNISVNADPTTLQPNLYFDMSGFSLNEKSDYIFNFLKTILMETDFSTHKDKLKVLINSIASSNTSHIADSGHTVARSFASGHLSTVAAIQEHISGVEHYKLISRLCSIMNDDKLFQSEVIDKLVMLQRIIVNSQNMEFFASVDCQAQENKIRKEVDYFVSTLPNTSSDISGAIQTACVPRYSDSQVLNLIKFPFQVHYTAQAYNGVSYTHKDGAALQVLANMLTFKHLHKEIREKGGAYGGGATFSALSGIFSYYSYRDPNPLASIQTFEKSASYVLNDAKWTQSDLDESKLSIFQQVDAPISPKSEGSTFFNLGVTDEMRQVRREQLLDTSLLDIHRVAERYILPNKSIATVVGPGIDGETVSPKWHIEDIKV
The following text describes a protein:
Function:
Plays a role in the regulation of phosphate uptake.
Subcellular Localization:
Cytoplasm.
Sequence:
MKRIEEKEKAIMDEIMEMHALAEKAVELSFRAMRGDKSVVREISRIEQQTDVLDTDINYACTTFIALFQPVARDLRFAISIMRISSSYERIADIAQEISLYESKLPEIVFKAEKYLKKMFDAVKEGYTKTEGLKERMTELDNAVDEIYVEAIEQLEESCDVNAVLTVRHIERIGDLLAKIAARQIFIKEGRRVWII
The following text describes a protein:
Function:
Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.
Subcellular Localization:
Nucleus.
Sequence:
MTKANGAEQLADWKFQYDLLTNELFHLHEFTSLLEFDPAFRHESDSFARFLADKHLELRMEEDAGAPGLEESSAMRRIRRRQKRGRGEEEGNALLKGVEELVEQKYADLRARLDRPMLKQGPRKRKQPGDAAKTALPHDSKKRKSAVVRKETNDEEHLKEEKSASPTVWSPESPQRDTYRTIHPSGDHEGYQSSSSDSFYFTTSSEDEEPTVKRSLKRKKAPVRRIKLIVHPPKQTVTNPLHILKPECSSLHEFLQSYKSLDEDISIEEFDSYIASQRKVVSAIRKGLKSGVLTYDRHTDSIQGISLKDVQNSQANKPEPITTFYQEQEKHTLRDHLNNHGVVMSRMFQDRKRGRIARARKISQMIEQHFKHVAGAEERKTKEEEKRRRALARAAVQAVKKRWNLAERAYKVLKKDEEDQLKRIQGKEHLSKMLEQSTQLLGAQLNQNDDSDDETSSQVLSENESSLGDEEMSSSSELDDSEVEAGEDDSKLTVEQLRAKYSALEHITIDGRSQNSEVSSMTENPEEDPQEYKILLSEREKAELHRTFETEENNILDEDHSSSSSFSESEISQTSSSENESLINSNSSQTPGLASLFGNVAEELSDDAHYSTEESLSSTPNEDQEGVQPNADAVSNMEIDSLEMQDKDESTNLEKLSVVDVPVPPLLRGTLRTYQKQGLNWLASLYNNNTNGILADEMGLGKTIQTIALLAYLACEKENWGPHLIIVPTSVLLNWEMEFKRFAPGFKVLSYYGSPQQRKEKRRGWNKLDAFHVCITSYQLVVHDQHSFKRKKWQYMILDEAHNIKNFKSTRWQALLNFNTRRRLLLTGTPLQNNIAELWSLLYFLMPQTALENGKISGFADLDAFQQWFGKPVDKIIAANDSEHDDETRRTVSKLHQVLRPYLLRRLKADVEKQMPAKYEHILYCRLSKRQRFLYDDFMSRAQTKATLASGNFMSIINCLMQLRKVCNHPDLFEVRPILTSFCMDRSVMSNYAHLNQLVLKNLNKHALDTVVNLQCTNLAFTQNDFNMETHYADSCARLQCVRQFSEAVEKLRKDASLPDAKDDPNVLNYQDMHEFYTGYTVRKRLRLIDQYRHTFYLNSLRCEKRPVYGINLVRLVSVHHRPPLECNVMSELMKPLETRLVTHKRIIDEFAIITPTAITLDTRVLSLGLDSEAAVHPVIKSDINTQLSRMKNPFHLLQTKLSIAFPDKSLLQYDCGKLQSLAVLLRRLKEEGHRALIFTQMTKVLDILEQFLNYHGYLYMRLDGATKIEDRQILTERFNTDPRITVFILSSRSGGLGINLTGADTVIFYDSDWNPAMDKQCQDRCHRIGQTRDVHIYRFVSEHTIESNILKKANQKRQLDNIVIQKGEFTTDYFSRLSVKDLLGSDETEEIADERPLLEDPATTADSKKLERLLAQAEDEDDVKAARLAMKEVDVDDRDFRESSTCANPSPDEDVDEEPVEDEYEGTRHVEEYMIRFIANGYLYD
The following text describes a protein:
Function:
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTSPDERKSFWERHEFKFYRYGHVYALIYGQVVIDYVPQRALKRGVKVLLIAYGHLFSMLLIVVLPGYFCYHFRTLTDTLDRRLQLLFYVSFTNTAIKYATVIVTYVANTVHFEAINQRCTMQRTHLEFEFKNAPQEPKRPFEFFMYFKFCLINLMMMIQVCGIFAQYGEVGKGSVSQVRVHFAIYAFVLWNYTENMADYCYFINGSVLKYYRQFNLQLGSLRDEMDGLRPGGMLLHHCCELSDRLEELRRRCREIHDLQRESFRMHQFQLIGLMLSTLINNLTNFYTLFHMLAKQSLEEVSYPVVVGSVYATGFYIDTYIVALINEHIKLELEAVALTMRRFAEPREMDERLTREIEHLSLELLNYQPPMLCGLLHLDRRLVYLIAVTAFSYFITLVQFDLYLRKKS
The following text describes a protein:
Function:
Probable transcription factor involved in plant development.
Subcellular Localization:
Nucleus.
Sequence:
MDNVRGSIMLQPLPEIAESIDDAICHELSMWPDDAKDLLLIVEAISRGDLKLVLVACAKAVSENNLLMARWCMGELRGMVSISGEPIQRLGAYMLEGLVARLAASGSSIYKSLQSREPESYEFLSYVYVLHEVCPYFKFGYMSANGAIAEAMKDEERIHIIDFQIGQGSQWIALIQAFAARPGGAPNIRITGVGDGSVLVTVKKRLEKLAKKFDVPFRFNAVSRPSCEVEVENLDVRDGEALGVNFAYMLHHLPDESVSMENHRDRLLRMVKSLSPKVVTLVEQECNTNTSPFLPRFLETLSYYTAMFESIDVMLPRNHKERINIEQHCMARDVVNIIACEGAERIERHELLGKWKSRFSMAGFEPYPLSSIISATIRALLRDYSNGYAIEERDGALYLGWMDRILVSSCAWK
The following text describes a protein:
Function:
May link the intermediate filament cytoskeleton to the M-disk of the myofibrils in striated muscle.
Subcellular Localization:
Cytoplasm, myofibril, sarcomere, M line.
Sequence:
MTLPHSLGGAGDPRPPQAMEVHRLEHRQEEEQKEERQHSLRMGSSVRTRTFRSSEEEHEFSAADYALAAALALTASSELSWEAQLRRQTSAVELEERGQKRVGFSNDWEGTEIAFLQTHRLLRQRRDWKMLRRRTEEKVQEAKELRELCYGRGPWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFPAGKYRITNNYGLLSLEIRRCTIEDSATYTVRVKNAYGQASSFAKVLVRTYLGKDAGFDSEIFKRSMFGPSVEFTSVLKPVFAHEKEPFSLSCLFSEDVLDAESIQWFRDGRLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRDAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYSIERCQGESGEWIPCHEAPGGTCRCPIQGLVEGQSYRFRVRAISRAGSSVPSKASELVVMGDHDAARRKTEIPFDLGNKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRGRAPLTYSLEKSVIGSGTWEAISSESPVKSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRDTQTSVSLTWDPVKDPELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVTQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTNPVLLEDKPGAHEIEVGVDEEGFIYLAFEAPEAPDSSEFQWSKDYKGPLDPQRVKIEDKVNKSKVILKEPGLEDLGTYSVIVTDADEDISASHTLTEEELEKLKKLSHEIRNPVIKLISGWNIDILERGEVRLWLEVEKLSPAAELHLIFNNKEIFSSPNRKINFDREKGLVEVIIQNLSEEDKGSYTAQLQDGKAKNQITLTLVDDDFDELLRKADAKRRDWKRKQGPYFEQPLQWKVTEDCQVQLTCKVTNTKKETRFQWFFQRAEMPDGQYDPETGTGLLCIEELSKKDKGIYRAMVSDDRGEDDTILGLTGDALDAIFTELGRIGALSATPLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRIRTGTTLDEIWLHILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRLKTLAIIEKNRAKVVRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKYGSETGQVTISVFKHGDEPKELKSM
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the export of sodium and potassium from the cell. May be an inefficient sodium exporter. May transport other cations such as lithium (By similarity). Sodium/potassium efflux ATPases are involved in salt tolerance and maintaining the membrane potential across the plasma membrane in high salinity (Na+) or alkaline (K+) environments.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSSINTNVAEKHSYKERVNTDASSLSADGSVEAHRLTIEQVAKIFNTDIINGLSTSQANQTLKDFGANTLGDGDKISLTKIIAHQVCNAMILVLIISMVIALAIKDWISGGVIGFVVLINISVGFVQEYKAEKTMGSLRSLSSPTARVTRNGDDTTIPAEEVVPGDIVHIKVGDTVPADLRLIDLMNLETDEALLTGESLPITKNHLDVYDDYSVPIPVGDRLNLAYSSSVVSKGRGTGIVIATALDTQIGQIAKSLRNNNSVIRKVDKSNGKPKKREYSKAFCGTIKDIFYNILGINVGTPLQRKLSWLAIFLFWGCRYFCNYCNGIPKNRVNKEVAIYAICVALSMIPSALIVVLTITMAVGAQVMVMKHVIVRKLDSLEALGGINDICSDKTGTLTQGKMIARKTWIPNVGTFNVGNSNDPFNPKAGEVSFVNLSPKFIEETDEEIDFKQKLPSPFPENFNNWLLTATLANIATLNQSRDEETGELVWKAHGDATEIAIQVFTSRLNYGRDSLIENYEHLAEFPFDSSIKRMSAVYQSLQTNQIKVYTKGAVERVLNCCTHWYGHEENDELYDNQQLKELTDDDKHLIESNMNALSTQGLRVLAFATKDITNSSIDLSNRESIESNLIFQGLIGIYDPPRPETAGSVKSCHNAGINVHMLTGDHPGTAKAIAQEVGILPHNLYHYSEEVVKAMCMTANEFDSLSDDEIDKLPVLPLVIARCAPQTKVRMIEALHRRGKFVAMTGDGVNDSPSLKKADVGIAMGLNGSDVAKDASDIVLTDDNFASILNAIEEGRRMSSNIQKFVLQLLAENVAQALYLMVGLAFIDDSGLSVFPLSPVEVLWILVVTSCFPAMDLGQERASDDILEESPNSTIFTWEVIIDMIVYGFWMAVCCLVCFVIIVYGEGDPYLGVNCNKSSSSNSDVCELVFRGRSASFATMTWCALILAWECIHPYNSLFYMRQDTDHPWWKQTVIDLWDNQFLFWSVAIGFISVFPVVYIPVINTKVFLHGPIGYEWGLAVGFSILFLAGSELWKWIKRIHKRKANKKAKNPEYELERSDPFKKYASFSRSNTMDRPELMV
The following text describes a protein:
Function:
Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEIFYYLVFGVLGLVVAALELSKNNKDRINTSSAFNSFKNNYLLVYSLMMAGDWLQGPYVYYLYSTYGFGKGDIGQLFIAGFGSSMLFGTIVGSLADKQGRKRACVTYCITYILSCITKHSPQYKVLMVGRVLGGIATSLLFSSFESWLVAEHNKRGFEQQWLSVTFSKAVFFGNGLVAIIAGLFGNLLVDTFSLGPVAPFDAAACFLTIGMAVILSSWTENYGDPSENKDLLTQFRGAAVAIASDEKIALLGAIQSLFEGSMYTFVFLWTPALSPNDEEIPHGFIFATFMLASMLGSSLASRLLSRSTPKVESYMQIVFLVSGAALLLPILMTLFIAPSKVKGGGISFSGCFQLLGFCIFEACVGLFWPSIMKMRSQYIPEEARSTIMNFFRIPLNIFVCVVLYNVNAFPITVMFGMCSIFLFVASLLQRRLMMIVDKPKTNDWTPLEERNTEEDPLNI
The following text describes a protein:
Function:
NAD-dependent protein deacetylase (By similarity). Has deacetylase activity towards H3K9Ac (By similarity). May have a function in the safeguard against genome instability and DNA damage to ensure plant cell growth (By similarity). Involved in responses to ethylene leading to the transcriptional repression of some ethylene-responsive genes via the regulation of histone acetylation H3K9Ac.
Subcellular Localization:
Nucleus.
Sequence:
MSLGYAEKLSFIEDVGQVGMAEFFDPSHLLQCKIEELAKLIQKSKHLVVFTGAGISTSCGIPDFRGPKGIWTLQREGKDLPKASLPFHRAMPSMTHMALVELERAGILKFVISQNVDGLHLRSGIPREKLSELHGDSFMEMCPSCGAEYLRDFEVETIGLKETSRKCSVEKCGAKLKDTVLDWEDALPPKEIDPAEKHCKKADLVLCLGTSLQITPACNLPLKCLKGGGKIVIVNLQKTPKDKKANVVIHGLVDKVVAGVMESLNMKIPPYVRIDLFQIILTQSISGDQRFINWTLRVASVHGLTSQLPFIKSIEVSFSDNHNYKDAVLDKQPFLMKRRTARNETFDIFFKVNYSDGCDCVSTQLSLPFEFKISTEEHVEIIDKEAVLQSLREKAVEESSCGQSGVVERRVVSEPRSEAVVYATVTSLRTYHSQQSLLANGDLKWKLEGSGTSRKRSRTGKRKSKALAEETKA
The following text describes a protein:
Function:
Probable mitochondrial mRNA stabilization factor.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MSATPAVLRASACSACRFSALRLFVSSFASPRAPLPVARTRVLSPTAPYSTFRPSPRLLASPSSEEHAEPAAQEQPNKTEDAQAEASTEANNEGGADVPWYLQVDAPTHPTLVHEPPPLPDIPEGSPKLMEPLVKFVSDELGMDDLKLLDLREIDPPPALGPEVLMLFGTARSERHLHVSADRLVRWLRNRGVTAKADGLLGRNELKTKLRRKARKAKLLGTTGLPSGADDGITTGWICVNLGTLGWSDMEMEFKDEKGVTSGFGVPQSGTTLVVQLMTETRREELALEKLWSGILRRSLERQDKIAGKLPEASFTTSPDTVSGQSFSPSPIRSSGRNRKRPDRLYFSTSARQHAAAVDVSQTDLATAMAGWEYSNASPSTIDNLLAQDTDSKVQLLIQMQEYLSSLPRDQALSAVSLCEDGSPSTFMRLFNRAIENLPSAQAWEARLWVEKAARALQHPDHDLARLGDLIQEMKLSGAANVSREKFVDLLRMIFAIPETTDAGVRQQASLSMDVIDMLFSRGEKVIEYDVVVAVIESLLQTRARPPEARRLLSQFEDLLSEAQMDCPTEDEIIRLLDVYANHRAWDKFWNVWRVFPRHCERRTERMYTKVYERIAAEDHQGMATDALRWCVEEMWHEQPPVRVTAAMLKALEACIRIADPEAESLAKDIDDRISDAQYMDREFVRLWLTLHGSAAWGA
The following text describes a protein:
Function:
Appears to function during host infection, and may play a role in suppressing the host immune response.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Host cytoplasm. Host nucleus. Host cell membrane.
Domain:
The CFEM domain is involved in heme-binding and contains 8 cysteines and is found in proteins from several pathogenic fungi, including both human and plant pathogens (By similarity). The CFEM domain adopts a novel helical-basket fold that consists of six alpha-helices, and is uniquely stabilized by four disulfide bonds formed by its 8 signature cysteines (By similarity).
Sequence:
MKFSAPVLAIFLASASAQSTAELAAQIPSCAQTCLATAITGAGCTAGDYACQCGTSQNTITASATPCVISACTSEEALNTQRTTSQICALVAAGSASSPSASSSASASASSSASSTSGAASASASASSSASSASAAASALTLAHPIPNPSHPPSPTIQTNLRKKVRNSNRLTPASLSSVSSALVSSASSVRASASSAVSAATTAANPAATTAAGVKEEASFFIPAAVALFAVFAV
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.
Sequence:
MAITELCHQLGQIDKELPSLLVNRLEQVYENGSSGVVEFFKAIDELCADDNAIYKESLFGLFARRVGLLYHRMTFSQISHFFTLFERYMSSAKPDVDCMDESLECTENEMHMEDKQDHKSDFMSFISSSSRQAEFFLSSQASAIQSNESQALPPQELQSKIFQLQRASNDIPETHYLSYLNSLRVGEYKQTVDSLHQYFDQQQGNKASSKPAIEGAEVMEEKGQSFRYAAMNLAALHSRLGHRYTGRGLSRSGGKWVLYIWALHNVLVHRDMGMLRVWSPWVLIGTRVHQGCDHHGSSQEYGYIKGVFTIGVNRDMGTSGVWSPWVLIGTWVHQGKEALLALQEAINMAQEKDDHVCLEHCLLLLYRLEQEGSTQASELLDRSVTRAKELKLPYMTSLSMLTQTRHDVHVGMPPPKVLQVLSNISTINSQNSLQDLTETTFATRAAVWQLYGKSRMSSVFNQMVLYRNAPTCSHTSGTTHKPSDTQVSSLTGQQSDMQDGEARCLSLCNLAKVYADQGLYDESQEIIQFCKQNFPKPTNLSKIWMVTEAIISHDAAVIQGNQDKAQEAAKQIAGLDTQQARYRTAVNMLLEGRFSEAHTLLLSIQEKCSLASLPPSPHYNKSSNKPRGEVELIRSVLIALAQLYILSGNPLSALTHLIDCLTLAGAHYQTESAARASLLIAQLQLLLGLPGKALELVKSNMVQILAHGSLYTQSCALFLLVKCEVAAHSPEGANEKRKSTLLSALPTLARALEGFRKLRAMQRICDLLYYQARIYNELGYQEERNHYSAECCKLLQDPLVKNTAGRSFCCL
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC).
Subcellular Localization:
Nucleus, nuclear pore complex.
Sequence:
MATTPVPFKHDALQPAGASPHYRGPWRKCLAQETHGRSSLSLSLCQTPIIFTALQADLEQLGADGTDEPARLQALLSYSLQYRAALRSIADNVFQHVETTAGLAPAVMEEEARLVQEFGHLEEAWHLCEIFFPRSILIQQAGGFIIPHLLEWLNLHCTELDRELKSILQHQTQLIDQNAAYWTTQMVAAWTDRFDAYPQAQELCRILAAEAGSASYLAKLFPNWLHHVIVYAQYWRPLCRIGEIEDLLLDLGLHVDETDLYLIILQQEPEQTILSLLSHFPTFWSPAHLADLLQRSRWFGAAPRRGAHNMTLREHYVISYALELAREDTLWPLAASYLASCGSVGQATLVEVLESRPQPSLSAVRKSMALARKHGLDITAKRIAICEAKRRQNSGQLDVAVQYFFEAGDLDAVTRIADAMLRTYAATGELDPTDLAQRLGPAVLQSERLTFIAKYKEALALIAEMHYEQAANILINVLSKSTMAPRWLHLHVLLDMLPILEQPDIVFDAEQTQTLMQCLQEVELSHNLREYTRYLLAKQPCHGEEGEKLDEDWDKIPLDQLRTQLATLLEPLRLALARNLARALVVSR
The following text describes a protein:
Function:
ADP-riboxanase effector that inhibits host cell pyroptosis. Acts by mediating arginine ADP-riboxanation of host CASP4/CASP11, blocking CASP4/CASP11 autoprocessing. This prevents CASP4 activation and ability to recognize and cleave GSDMD, thereby inhibiting LPS-induced pyroptosis (By similarity). ADP-riboxanation takes place in two steps: OspC3 first catalyzes ADP-ribosylation of target Arg, and then initiates a deamination to remove one N-omega group (By similarity).
Subcellular Localization:
Secreted. Host cytoplasm. Note=Secreted via the type III secretion system (T3SS).
Sequence:
MKIPEAVNHINVQNNIDLVDGKTNPNKATKALQKNILRVTNSSSSGISEKHLDHCANTVKNFLRKSIAAQSYSKMFSQGTSFKSLNLSIEAPSGARSSFRSLEHLDKVSRHYISEIIQKVHPLSSDERLLLSIIINSNFNFRHQSNSNLSNNILNIKSFDKMQSENIQTHKNTYSEDIKEISNHDFVFFGVEISNHQEKLPLNKTHHTVDFGANAYIIDHDSPYGYMTLTDHFDNAIPPVFYHEHQSFFLDNFKEVVDEVSRYVHGNQGKTDVPIFNTKDMRLGIGLHLIDFIRKSKDQGFREFCYNKNIDPVSLDRIINFVFQLEYHIPRMLSTDNFKKIKLRDISLEDAIKASNYEEINNKVTDKKMAHQALAYSLGNKKADIALYLLSKFNFTKQDVAEMEKMNNNRYCNLYDVEYLLSKDGANYKVLEYFINNGLVDVNKKFQKANSGDTMLDNAMKSKDSKMIDFLLKNGAILGKRFEI
The following text describes a protein:
Function:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
Sequence:
MRQIILDTETTGLEWRKGNRVVEIGAVELLERRPSGNNFHRYLRPDCDFEPGAQEVTGLTLEFLADKPVFAEVVEEFLAYIDGAELIIHNAAFDLGFLDNELSLLGDQFGRIIDRATVVDTLMMARERYPGQRNSLDALCKRLGVDNSHRQLHGALLDAQILADVYIALTSGQEEIGFGAMDAGQHAEGGEGMIAFDPSLLLPRPRVVVTPSELQAHEARLERLRKKAGRALWDAPELDEVAVAS
The following text describes a protein:
Function:
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subcellular Localization:
Cytoplasm.
Sequence:
MAPSFDHLRDEDLDEDDFDVDEVDISDIREKYEVQLEQGYDAFVVVDGLPEVNEEQKPKLVKFLLKKLNTVGKTREDLIFMPMGEDGKSLRFAFVEYSSPAEAAAACRQLDLVPLDKKHTLRVNKLTDVDRYGREGRIDDEYTPPKIEEFQEKEHLRSFMADPSGRGRDQFVMFRGESVGVFWNNEKDTPENIVDRQHWTETFVQWSPLGTYLTSVHAQGVQLWGGPSWTRQRRFAHPFVNLVAFSPNEKYLVTWSNRPISIPEEGHPALSVEDDGKNYVIWDIETSKPLRSFAQLDTPAAAEGEAPKKAPKFPWPAFKWSADDKYVARLNPGQSISVYELPRMNLLDKTAIKIEGVVDFDWAPATVQRDGVKSYEQLFCFWTPEIGSNPARVGLMSIPSKQVVRSLNLFSVSDAKLHWQSEGAYLCVKVDRHSKSKKSQATTLEIFRVKEKGVPVEVVDTIKDTVINFAWEPKGDRFVIITTTEPVGATAVPPKTSVAFFCPEKAKGNAVGNFKHLRTLEKKNSNAIYWSPKGRFVVVATVANTQSSDLDFYDLDFEGEKPESDKDLTANLQLMNTADHYGVTDVEWDPSGRFVATWASAWKHSMENGYHLYDFKGEQLREEAIEKFKQFQWRPRPATLLSKEEQKAIRRNLREYSRIFEQEDAERISSADVAVVEARRRLLEEWFAWREAIRQEVAEEREIYGLPADPVADLIKAKTPELATDQEEQVIEEIMEEVLEETEEIVQ
The following text describes a protein:
Function:
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Sequence:
MEKFELHILGCGSALPTTRHFATSQVVNLREKLFMIDCGEGAQMQLRRSRLKFSRLNHIFISHLHGDHCFGLLGLISTFGLLGRTADLHIHSPKGLEELFAPLLSFFCKTLAYKVFFHEFETKEPTLIYDDRSVAVTTIPLRHRIPCCGFLFEEKQRPNHIIRDMVDFYKVPVYELNRIKNGADFVTPEGEVIPNHRLTRPSAPARKYAYCSDTIYRPEIVEQIKGIDLLFHEATFAQTEQVRAKETHHTTAAQAAQIALNAEVKQLVIGHFSARYEDESVLLNEAAAIFPQTVLARENMCITINNYTDTRDYDPL
The following text describes a protein:
Function:
This protein lyses red blood cells and has cardiotoxic and hypotensive activities.
Miscellaneous:
MISCELLANEOUS: Is classified as a P-type cytotoxin, since a proline residue stands at position 31 (Pro-31 in standard classification).
Subcellular Localization:
Secreted.
Sequence:
LKCHNKLVPFLSKTCPEGKNLCYKMTLMKMPKIPIKRGCTDACPKSSLLVKVVCCNKDKCN
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNGEFVAFFILSLSAIIGGVLMLNLTKVMHMMLALVLTFLSIAGLYFLLSAEFIGVAQILLYSGAITIIMIFGIMLTKHNAENESRLTLRKWIIFFAVVAFGAVMYFAVNNVDFANESTQGSLPLHENNTLQIGTLLYSKYIIPFELTSVILLVALVGAIILAKKDEKEEDSNE
The following text describes a protein:
Function:
Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.
Subcellular Localization:
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.
Sequence:
MSLKVYQAETGILLPLQRLVPGDTVDMLRADIEAVTFIPQKFQVLLGSNAQIVKQSMLTTLLSSQKDERIFIFNRLALMQQTGNKPVHMSIDIEPPVPSDTVVGLKVISPLAPNLSSKERVIAFKRAFSEHISYGQALRKIANKHAKTCERLLEEQSIQVEGLTMALCNLFTHRKSVLDSYDSFIAPAQIQISSHTELLHGIASDLDTLTMIPIHEAIVSESKVLNDYIPRDKLLRWINDCRVAHDELVDKVQSISVTMNDVRAGARIDQLEPEDFDLSKLDPLLDIVRKLVGQIESRQNILERDFTRVETILADISNGPDDQAGDRFEALEHLYKIHFEEYIPEITRCDRQVRETVVQFSDSKAHLTQALMEKLLELAKQQSTIYIIPQALMALDKELRVQAEAFLQLLHVHRMPPAWGAAFIEIVRRREHSKVLGDKVNQIMGILTSFQNQEEARRDTFRTEIERYLPKGLLKGLESATPSIKLSISEDEILLPNLTKDDVTAFSQMVASLRAIQDPSTVQTSGSLSKLHAMMVQMSPQVDSPLLDFEELISNSTFCDRIVKLEAENAKLRKEVVEMRAQAAPVSQTSTAFRHPSMNDVLSSSHSTKQEEKIKAYEARIKNLEQLLQQSYSTSGAVEKTHVTDRRLMQEMESTIQTMTLEKERILKENQQFCDQLQQSTQRISELTTLYQNVRESHDKLRNEKQTTDVQLSNTLVELKKLQDFLVEVREYMEGCCLSLRRDTGSEQKSDIEEQTPVQLNHIRSKPASIDELRRCMRVLKDDILWHAAMMESMKNSMQDSQDGSDVTQSVAAEMVTLIQRLGETEERLRIAENDLTVAQAHEAVLEADLESLKVLYERAEGHVAAAKVQRNEHQAQQEKNALELKRLQDLQESQIEQHRTSEVVLQKQIEQIKKELEQTQADSMADIESQKQAHTKAIEQMRLDMQQDLSQRELSRLAFSQVQQMREQIEDWNIVCRLSLQHLTGCLDALVRLVQHTLSEDVVYALIRNNGLTGSTENCCLSKLSDTFSISDAGAHYDDTKSLIEGFGNDDDALGGMSKFIEHYDLLLRELYSKVVSAGAYLDVSDSVDRIEKRWSDLTGQASFRVAFQNFKINDLVLFLPTRNPAAWTAFNVNTPHFFLDIQPNSVFADRIQQRGWILAYITGITDKTATDISLSPTNPFGLAEETRYHICQATPY
The following text describes a protein:
Function:
Catalytic subunit of the THUMPD2-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotides, most probably at position 72 (m2G72), in the U6snRNA of the major spliceosome. This modification in the U6 snRNA affects the constitutive splicing efficiency of introns that have suboptimal splice sites and can impact final mRNA levels.
Subcellular Localization:
Nucleus.
Sequence:
MFFRFIVSSMYPLSVKVEYVSGKVFFTTGADLDTLKKLKSAERLFLLLDKYPPLAVSRNKGKVVHDIQNLVKENPSCWLDIVAFWKHLHDQDSNPGVLPQKCPNSQKRKLEDERNIIKNKKQKSDPVLERVPAEGQVEKQQRCDISEAHKDSDVSQVSPFIETAPEHLQEKPLESNSYFSFRVSCRCSGLLAKTFTAQEMGRIIGIALMKNFGWKADLRHPDIEIFVHLNDIYCIIGIPVFRLPLSNRAYIRTIGLRSTIAWAMVSLAEIKAGAFVLDPTCGLGTILLEAAMEWPDVNYLGTDISDAQLQGAYTNIKAANLMDKIQLLKASVTALPLPSESIDVVLADIPFGKKFKITKDMELLPDVFQELERVLCAGGTLVLLLSRELYMCLAHGINSGPESENHISVEVANDCTQSAMISIKSSRKDKDPSLVNEVKEHITNHHRTAFGSLVLVESFEVSLGKTDAFICKYKKPIATPTKR
The following text describes a protein:
Function:
Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation (By similarity). Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MCTLQLHLLLLVVLMLSETARPQPSSTARAFPTSWGLEPVTPEVPTSAPPDSSESPTPWTLSMPVNATTDPFPALPICVCDLTPGTCDLNCCCDKDCDLLHPRTVFSFCLPGSVRSSSWVCVDNSLMFRSNSPFPSRVFTDSSGTTQFCVRVNNSKANYFQKLQTVNATNFQALAAEFGGQSFPSMPPETQPPVLFYRAGDPILTYYPSWSVVSLLRQPAAVGAGGLCAESNPAGFLESKSTTCPRFFRDLASSCTSEPALDAASYYNFRVLKVPRGVTDLQNMKFQVPVTLASQASPPLLAGNTCQNIVSQVVYEIETNGTFGIQKVSVSFRQTNLTVKPGVSLQQDFIVHFRAFQQRKAAAPAAPRSGNPGYLTGKPLLVLTGDTSHSMTLLQSEGNGLCSAKRHAVQFGVNAVSGCQLRPREVNCSHLQEEVYQTLHGRPRPEHVAVFGNADPAQRGGWTRILSRDCSVSAVNCTSCCLIPVSLEIQVLWAHLGLQSNPQAHVAGARFLYQCKSVQEHQRGIEVSLTTLVNFVDITQKPEPPRDQPRIDWKLPFDFFFPFKAALSRGASVQKDSLVLILCVLLLGLLNSQTK
The following text describes a protein:
Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MPQLVPFYFINILSFGFLIFTVLLYISSVYVLPRYNELFISRSIISSL