lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
Subcellular Localization:
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Sequence:
MVHQSEMENYNIGQASIEEVSDPAYKGAKIVVIGVGGGGSNMIKHLVEYGVHQDVTPIATNTDGQHLKNNPAPVKILLGKESTGGLGAGGIPDIGRKAAEESANEIKEAIKDAKLVIISTGLGGGTGTGATPTIVKIAKEVGALTIAIVTKPFKYEGNQKRKRAEEGLKELEQSSDSILVIPNDKILLTMKKNASTTECYREVDDVLVRAVSGISTIITKPGNINVDFADLKSALGFKGFALMGIGEATGEESAKLAVQNAIQSPLLDDASIEGAKSIIVFFEHHPDYPMMAYSQACDFIQDQAHQDVDVKFGQHTSDNIPIDHVRVTIIATGAERNSGGASLESIATPSQPVVKQTRKVGNGEYLKIPTEEELSIPTTMRIQQD
The following text describes a protein:
Function:
Plays a role in inhibition of host innate immune response. Reduces TNF-alpha-mediated NF-kappa-B activation. Interferes with IKK kinase activity and reduces the phosphorylation of both components CHUK/IKKA and IKBKB/IKKB.
Sequence:
MAHEPIPFSFLRNLLAELDASEHEVLRFLCRDVAPASKTAEDALRALQRRRLLTLSSMAELLCALRRFDVLKVRFGMTRECAGRLLGHGFLSQYRLQVAAINNMVGSEDLRVMCLCAGKLLPPSCTPRCLVDLVSALEDAGAISPQDVSVLVTLLHAVCRYDLSVALSAVAHGHMTVGVGTPVQDEPMDVLEVDDAEPMEATPACDEIGVVKLAGAASAGAPLADGAFAACTSAGKGEDLATSDLTDSEPEDSVFAVADPVYADVDLSMFVRANATADSSMFVNADAGADSSLVNADAGADSSLVNADAGADSSLVNAVADANSSLMRTTSACTDSEPEDSAGPSCAGMALSMFGRAKSVSSLLLRTKASY
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity). Specific peripheric component of RNA polymerase III (Pol III) which synthesizes small non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs from at least 500 distinct genomic loci. Enables recruitment of Pol III at transcription initiation site and drives transcription initiation from both type 2 and type 3 DNA promoters. Required for efficient transcription termination and reinitiation (By similarity). Pol III plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-kappa-B through the RIG-I pathway (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSEGNAAGEPSAPGGPRPLLSGARGLIGRRPAPPLTPGRLPSIRSRDLTLGGVKKKTFTPNIISRKIKEEPKEEVTVKKEKRERDRDRQRDSHGRGRGRPEVIQSHSIFEQGPAEMMKKKGNWDKTVDMSDVGPSHIINIKKEKRETDEETKQILRMLEKDDFIDDPGLRNDIRNMPVQLPLAHSGWLFKEENEETDVKPRLAGPKEEDMEVDMPAVKVKEEPRDEDEEAKMKAPLRAARKIPGLPKDVSVAELLRELSLTQEEELLFLQLPDSLPGQPPTQDIKPIKTEVQSEDGQMVVIKQEKDREARLAENTCTLADLTEGQVGKLLIRKSGKVQLLLGKVTLDVTMGTTCSFLQELVSVGLGDSRTGDMTVLGHIKHKLVCSPNFESLLDHRHR
The following text describes a protein:
Function:
Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses (By similarity).
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein; Periplasmic side.
Sequence:
MNTFFRLTALAGLLALAGQSFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDEAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTVLGDELRTGKLDVFYDLYNLAQKRRFERYQYALKVLERPMDFTGNDTFNLDRSKAPWPKDEAELNALWDGKVKFDELSLKLTGKSDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSLVAGGPAAKSKSISVGDRIVGVGQAGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRIITLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVNSIVIDLRSNGGGALTEAVSLSGLFIPSGPIVQVRDNNGKVREDSDTDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYGRALIVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAAKYVKSDDLAPFGPELLKEHNARIAKDPEFQYIMKDIARFNAMKDKRNIVSLNYAQREKENNEEDALRLARINDRFKREGKPLLKKLDDLPKDYQEPDPYLDETVKIALDLAHLEKEKPAEQAAANK
The following text describes a protein:
Function:
Plays an important role in regulating the size of autophagosomes during the formation process.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Sequence:
MGDPSSSPWMSRKSTFLIALTLVALIGIVQSEDFYELLGIERDADAKDIRRAFKRLALTMHPDKNQDDPKAHDKFVRINRAYEVLKDDDLRKKYDRFGEEGLKEQNQRYNKYESWQFYKTEFGLYDEDPEIVTLSKSDFEQSVFGEDIWIVNFYSPRCHHCHDLAPAWREFAKEVEGVIRVGAVNCWDDRPLCTAQNVKRFPTLFVYPKHEEYTGTRSLEPLVKFALNLVDVTIHPLWIGNFKKVLLADEAKDHPWLISYCGSPVGTEDEDTHDMASVGCLDRDDQLKLAAILNKVVSVGSVDCSASSQLCTKLKIEESTIRFYNKAKEVTKGGKELELEQPKQMADEILKQLPDLSSFTSAELQEARQALEVGGEAPPVVTYFMKKAGDDDLELKKLPHLLTDMKVRKFNCSTDQALCDDLYLGTHLPKVALFRKGGGHEFHHGRLFAQDIAAFARHGLTSRLRVLGPKDFPDPVINSGELWFVDFFSPHCPPCKQLLPEVRKAASRVPYVNFGTVDCTTHQALCSQQNIRSYPTTVFFNDSKPHVSVGFSNSHAIQEFIEDTLNPKVITLSQDLFDSLVKNRAKGDLWLVDFYAPWCGPCQALMPEWRKFAKKLNGTAHVGSVDCVEHSSLCVQLGVNSYPTIRAYPMGRTGAGGFSAYQGWNRDVMALMGWVQNFLPTSVEIITQGNFRDLVLRSTDPWVVDFYAPWCGPCMAYMPSLEEVAKALKGYVRVGKINCQSYQSTCGQASIQSYPSLRIYKGTETKGYSQNWFGEQVYQKEPQYLIPYLKQKFTKNLESTGQIKDEL
The following text describes a protein:
Function:
Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein (By similarity). May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway (By similarity). Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (By similarity). Acts as a regulator of the cGAS-STING pathway by catalyzing desumoylation of CGAS and STING1 during the late phase of viral infection (By similarity).
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Cytoplasm. Note=Shuttles between cytoplasm and nucleus.
Domain:
The N-terminus is necessary and sufficient for nuclear envelope targeting.
Sequence:
MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNPSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGYNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHRTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTEKMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNIDLNLLEWTHYSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MADRLTQLQTCVDQMLTQYFSALTHINTNHGFKSLAGEELVKDDTVPVVTDEERERTLEELAKDLVVKSQQIDYLIDSLPGIGSSEEHQMQQIEKLQKELEHYDQVTEDVIKEKDELLEHCDELILKLAQRKAHIDVESM
The following text describes a protein:
Function:
Probable protease. Involved in axial budding.
Miscellaneous:
MISCELLANEOUS: Present with 623 molecules/cell in log phase SD medium.
Subcellular Localization:
Bud neck. Note=Mother-bud neck and division site remnants of haploid cells.
Sequence:
MSLREVTNYEVSFYIPLSYSNRTHKVCKLPNGILALIISDPTDTSSSCSLTVCTGSHNDPKDIAGLAHLCEHMILSAGSKKYPDPGLFHTLIAKNNGSQNAFTTGEQTTFYFELPNTQNNGEFTFESILDVFASFFKEPLFNPLLISKEIYAIQSEHEGNISSTTKIFYHAARILANPDHPFSRFSTGNIHSLSSIPQLKKIKLKSSLNTYFENNFFGENITLCIRGPQSVNILTKLALSKFGDIKPKSAVKERSISIRTRSFRRSKSLKKRQDSSKNDYSDLKTFKILNTTWEKKYKNTMCFQQFPECNSIFINSNKVPIMRLLFPVSDKNTRFTKDDIKIYSHLWCELFGDESPGSLSYYLASKGWLTGCFAFTSEFAIGDIGLILELELTNSGWENIKRITTIVLNRLLPSFYVMNIDYLITFLKEQNLIDLVSFLYQSSEDLPMEECSKLSGILQDDLECLTPPNIFKGFKSLIEIDDPNIEKYENTKANIQWWTGQAIKFQNFLKSFMNHDNMRLLLLGNIKSGNIFDKMKNKSDICTDFFYEFEYYTANVHLASDNKFHSNSSYEFNFPTGNLFLPDCVSDPLKLQQLFLECSLKSKFATLRPQIYSEPTRTKPQLVSENQNYEMWILKEDPNFASDNKSVVSFEVLGLGIKPSPEATIHLEVLAQALFIITSSFLYPALRIGYTYEIASSSKGNVTLRFTISGFPEGVFTIVKTFVDTLKLIATDPTFLSKDTLRKARILVRNKYKNASSDNCVKLASVGLLIVLEKYIWTLEDRINALELTELESFEKFCFLFWRNPKHLVLFMQGSLEYADAINRYLNNNFTQHLKISNEGSKPTIRLYPPPSTKDLDQGTNAFISYNGHQDDPNNSIVYFIQTAQRDDIKNLTLTFLTEYLFSLTLVPDLRNKKQIGYIVLGGLRVLTDTVGIHITVMSGSSGHNLETRINEYLSYLQLQVLNRFTEFDFRRILLEPFLNLLKQNSTKQFEGSAGPVDLLNEIVANVQNGDNYTLNNKQMRQHRKVRNKIAEGRLNFQEDHEMIDISFLQKLTLKKYLAFFESKISIYSAQRSKLSIMITSPMAEKEIASRKMFLQLEAFLKINGFAIKNEDLKKIVEHSKGNPILLVKNLFTYFRRRNEVFKLGTVVLQEILKIIGMNLKQRYGSILGFSSQDGEGQEIEKFWNNDTSPIVPLQELPEPNFFRKAAF
The following text describes a protein:
Function:
Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins. Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAIILKEVSAPTAGIKITTPNVQAFHNSDSLGNGTLYVTGSEVTWISSAPGSKGFSVTYPAIVLHAISTDTTTFPSEHVFMMVDQRKSIRRRRAPILRTIQEADEQRGLELAAAELEGEESDNDDEEGPGLEIRFVPDDKEALTPMYHEILKGQEENPEEDDMMFEDEEEQEDGEYEMEEGDEQAMGSGQWFTADNIDQLQMSEEGLANMQRIFGRGDQQPRQDDSME
The following text describes a protein:
Function:
Essential component of the GPI mannosyltransferase 2 complex. Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MREFRLIFVLLFFLPSFAIANTEIINVETGDSNKLLTSNSVCDIELSNNSSIPLLLKPNPTIPQAAGAPQQSKYTFSVCGLKPLQKYQIRASWPAVYPSDIILNYNITHIIVEINASFYSHNESLMKRPPLVPLRLVVEPLLLGFLPKSVLPIVGFVFVIILIALICMTNLFIKHKRD
The following text describes a protein:
Function:
Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate.
Sequence:
MTAPLVKVLHRMQELFSNIVAALEAMIVFPSLFRDPSRKRRKTFHGAYWRRRTLDNFAEEVDRLFTSPLSLRNMIIMSEKIREQFKSCLQSSPVCMLPSYNHALPSGTEKGTYLALDVGGSTFRVALIELGGAGAMKILQESSSPIDNDVKLLEGTLFFDWMAEKIESMLSAVGADYGREAVPLSMGLSWSFPIEQTSISSGLVIHMGKGFLCSNGTLGQELGDLIVQSCRRRSLNVRVDAIVNDSSAALLSRAYVDPKTRMSLILGTGTNVAVHFPVREIGLTKFGTRPPGWFDYAKHVIINSELSMFGGGILPMTRWDDILNQTHLRPDYQPLEYMVTGRYLGEIVRLIITEAVETANLFRGELPHSMRDPYSFDTSIVAFLEADTSPSLVPSAALLQKEHTFPVSPSVEDLRFLRRICQIVSKRAAGYLATAIHSMWCLRNDAEFSDPTESKASSVKDTQEITIVESEEDSRSLSIACDGSVINKYPGFRDRCQGYLNQLTQQTNSSQGPLDPATSPYIRLELAPESAILGAAVAVAVAVEDQKSG
The following text describes a protein:
Function:
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes adhesion and migration of various cells via the alpha-V/beta-3 integrin receptor (ITGAV:ITGB3).
Subcellular Localization:
Secreted.
Sequence:
MKTALILLSILGMACAFSMKNLHRRVKIEDSEENGVFKHRPRYYLYKHAYFYPHLKRFPVQGSSDSSEENGDDSSEEEEEEEETSNEGENNEESNEDEDSEAENTTLSATTLGYGEDATPGIGYTGLAAIQLPKKAGDITNKATKEKESDEEEEEEEEENENEESEAEVDENEQGINGTSTNSTEAENGNGSSGGDNGEEGEEESVTGANAEGTTATGGQGKGSSKTTTSPNGGFEPTTPPQVYRTISPPFGKTTTVQYEGEYEYTGANEYDDGYEIYESENGEPRGDNYRAYEDEYSYFKGQGYDGYDGQNYYHHQ
The following text describes a protein:
Function:
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
Subcellular Localization:
Nucleus.
Sequence:
MTDKPFFYSCYLLRSCQPGRRIPAYIGSTLDPSRRLRQHNGLIKGGAQQTIKWRPWEMVAIVYGFPSDVTALQFEWAWQNPHKSRHFKKDQFSETRSNMVVKGKLKVLSKMLHLEYWARWPLKIQFTVLDVQEMFKTFQAPPPHIVVTFGSVSTVNVGIVSPDIPDLQTETDCIICYETLNLQDQSSWLRCSRPKCKMRGHLVCLSSWFIEEECQSLQDRQCMQLLPINGTCPICRLNLVWGDLVADLKLRVSGLVQVRSSIDGECIDPNRGETNCTDLDAVDISDDDLVIDLNDFISNASLLDTPYASGSSRCIDTESAARSVLKPSGSHRSCAPTSDNGYMHQPAPSSRCISNRSASSIRQTLPSRPMPITITLLDDSDNESGHVQSKITRRSTASSNLVPSIGSNPSSHNGTTRLTNTRQLADHQELTSDDDDDLLNALLVGNR
The following text describes a protein:
Function:
Participates in the catalytic exchange of histone H2A for the H2A variant HTZ1, an euchromatin-specific factor, leading to chromatin remodeling and changes in transcription of targeted genes. Indirectly involved in vacuolar protein sorting.
Miscellaneous:
MISCELLANEOUS: Present with 358 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSDEGADKSLDTNTEFIIQTRSRRSNAGNKLQKLLEQELRDIESTKRQISSYKNGNDDEEDEIGLLFQEDEDDEDFEMMAKDDDDEGEEKEDETQSIRKEPSQASSEQAADDLMFSSSESEDSSNENDEDAEEKEIRRQELLSRKKRNKRLQKGPVVIKKQKPKPKSGEAIPRSHHTHEQLNAETLLLNTRRTSKRSSVMENTMKVYEKLSKAEKKRKIIQERIRKHKEQESQHMLTQEERLRIAKETEKLNILSLDKFKEQEVWKKENRLALQKRQKQKFQPNETILQFLSTAWLMTPAMELEDRKYWQEQLNKRDKKKKKYPRKPKKNLNLGKQDASDDKKRESEESIKNDGDVNSLGENSSSVHNQKRIEETSTNDTVEGESSPDAAVSRVNSDELKPTALPDVTLDAIANKQSTVDEAPNSQPQKNIITNEQKITNVGEPIQNLHNEEIKDEMVSALESRENTFENSSPAAQVVSQRDNSATPTPSNSTGTEDTILISPDTDIKGEPEPCLKTEGIENLSHNVPQETKSNTDVSFLKQVTFTDHPQVAIIDTEESPSKKDTANVDESSAENSLSTQTYEGPEQLTSRNFVTLYDFPNAPPNLKDFNTNLFGDRWSYTNGLSATQRPQDMKTVFHSILPSPPQSSVPSPTVDISLDLSALANFPSFGEYDKKIVHQINTEINKDLEIKIKTQPPTGVFLANGIRKKCLITNKECQYFDPRTGVPYSDVEAYKIIQRIQDPISKEEGRSDIKRDETTNEDSDDQVRFKWFGFKNGGIYLDLSQRPAKGVPEGF
The following text describes a protein:
Function:
D-mannose/D-glucose-binding lectin.
Miscellaneous:
MISCELLANEOUS: Binds one manganese (or another transition metal) ion and one calcium ion. The metal ions are essential for the saccharide-binding and cell-agglutinating activities.
Sequence:
ADTIVAVELDSYPNTDIGDPNYPHISIADENSLHFSFHKFSQNPKDLIL
The following text describes a protein:
Function:
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway. In vitro, the flavin reductase Fre can substitute for the function of RutF, however, RutF is required for uracil utilization in vivo.
Miscellaneous:
MISCELLANEOUS: The Rut pathway degrades exogenous pyrimidines as the sole nitrogen source at room temperature but not at 37 degrees Celsius, a restriction that is apparently a consequence of an inadequate ability to remove toxic malonic semialdehyde at the higher temperature (RutE/YdfG function).
Sequence:
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPAFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
The following text describes a protein:
Function:
Enhances the ability of BRLF1 to induce lytic infection by cooperating with it to transcriptionally activate the BZLF1 promoter.
Sequence:
MASSNRGNARPLKSFLHELYLKHYPEVGDVVHLLNTIGVDCDLPPSHPLLTAQRGLFLARVLQAVQQHKLLEDTIVPKILKKLAYFLELLSYYSPKDEQRDIAEVLDHLKTNRDLGLDDRLWALIRKLRQDRHHASVNVLMPGSDYTAVSLQYYDGISIGMRKVIADVCRSGYASMPSMTATHNLSHQLLMASGPSEEPCAWRGFFNQVLLWTVALCKFRRCIYYNYIQGSIATISQLLHLEIKALCSWIISQDGMRLFQHSRPLLTLWESVAANQEVTDAITLPDCAEYIDLLKHTKHVLENCSAMQYK
The following text describes a protein:
Function:
Lyase involved in the degradation of nitroaromatic compounds. Catalyzes the conversion of 4-hydroxylaminobenzoate to 3,4-dihydroxybenzoate (protocatechuate). Required for the catabolism of 4-nitrotoluene.
Sequence:
MNKRDELIGLCIDFLAKVKDKTANANIERWLNENYGPDSETYQKISTLVIDGVAEGWAANDEISGPHYRRSRLCEPCAETFYFSITAVYMDSKGHELDNQQRTFRGDYHSHPYGELNMVIPLDEGAVLAGPLGWQGAGWTAPAPGSQHYPEVKNGALIAFFFLPAGRISYDFQAQG
The following text describes a protein:
Function:
Exporter of leucine.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVGRGVKGGYLAACGVFIGDAILMFLAYAGVATLIKTTPVLFNIVRYLGAFYLLYLGAKILYATLTSKGRAATETVVPFGAIFKRALILSLTNPKAILFYVSFFVQFIDVTAPHTGVSFFILATTLEIVSFCYLSFLILSGAFVTHYIGTKKKLAKVGNSLIGLLFVGFAARLATLQS
The following text describes a protein:
Function:
Transcription factor involved in auxin response. Functions in auxin signal transduction and modulates lateral root growth. Interacts with ARF response factors to promote auxin-responsive gene expression. In response to auxin, binds sequence-specific motifs in the promoter of the auxin-responsive gene IAA19, and activates IAA19 transcription. The IAA19 transcription activation by MYB77 is enhanced by direct interaction between MYB77 and PYL8.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing MYB77 exhibit stunted roots and shoots.
Subcellular Localization:
Nucleus.
Sequence:
MADRVKGPWSQEEDEQLRRMVEKYGPRNWSAISKSIPGRSGKSCRLRWCNQLSPEVEHRPFSPEEDETIVTARAQFGNKWATIARLLNGRTDNAVKNHWNSTLKRKCSGGVAVTTVTETEEDQDRPKKRRSVSFDSAFAPVDTGLYMSPESPNGIDVSDSSTIPSPSSPVAQLFKPMPISGGFTVVPQPLPVEMSSSSEDPPTSLSLSLPGAENTSSSHNNNNNALMFPRFESQMKINVEERGEGRRGEFMTVVQEMIKAEVRSYMAEMQKTSGGFVVGGLYESGGNGGFRDCGVITPKVE
The following text describes a protein:
Function:
Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Subcellular Localization:
Mitochondrion.
Sequence:
ASRSQAEDVRVEGAFPVTMLPGDGVGPELMAAVGVIECLKLGDGLFLQCCEEVAELYPKNIANPTATLLASCMMLDHLKTSDMGGYATCQDFTEAVIGALSHP
The following text describes a protein:
Function:
GTPase that plays an essential role in the late steps of ribosome biogenesis.
Sequence:
MELAAEEGFDIEDVEGAIEEAGHGPLPVLAVVGRPNVGKSTLVNRIIGRREAVVEDKPGVTRDRVTYEAEWAGRRFKVVDTGGWEQDVLGIDASVAAQAEYAIEAADAVVFVVDAKVGATDTDEAVVRLLRKAGKPVVLCANKVDGPSGEADASYLWSLGLGEPQPVSALHGRGTGDMLDRVLEALPEAPAQTFGTAVGGPRRIALIGRPNVGKSSLLNKVAGEDRVVVNELAGTTRDPVDELIELGGVTWKFVDTAGIRKRVHLQQGADYYASLRTAAAVEKAEVAVILVDASESISVQDQRIVTMAVEAGRAIVVAYNKWDTLDEERRYYLEREIETELGQVAWAPRVNVSAQTGRHMEKLVPAIETALAGWETRVPTGRLNAFLGELAAAHPHPVRGGKQPRILFGTQAGTKPPRFVLFASGFIEAGYRRFIERRLREEFGFEGTPIHISVRVREKRGAKKK
The following text describes a protein:
Function:
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions.
Subcellular Localization:
Cell projection, cilium membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MSGKNPFFDEGTAGSGGAGSSWNDWEDVGKESTDYDSKNDYGFDFQSKQMEIDRRKQNMLSSTQRSMGLMYEAEQVGNETAAELLHQGEQLQRVDTKLDKMDKDLDISKRHITSMKSIFGGIVNYFNKPKPDQQEQAAPPRGPSKLKTHMERSEAEEEMRRANTDHPALKLRGVGASETNAGGWGPSSTAGFGAEDDGGVGSTSNVLQSPGMKDFDNQLNSNLDDITSGIGRLKGLAMGLNDELDKQNDDIDRITGKVGRVDVKLGQTDKEVKKILRR
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MYPCLHSSVLNHLFSYYEDENPEENLRDPVAAYKLLCRLREELIYIIETIQSIIDVSQCDEFQDELKTTLIPQYEDLDGAASGLIRLQEIYKLYPEDITKETSLDADEAFHVGRVAYKEYKFQHAFLWFSYSGIRWTENSSTNEKDLLHYLSLSAKHFGSLPWAIYYSQELLYLNPYDNEVKLQLNRLLHFQKSPNPNIFRLDSLSSNYEALCRGEVDERTSKRQRALSCRYSTSGGNPRLMYAPVKEEELWDEPKIIRFHDVISDTEIETLKDIARPQLSRSGVYQDGQGKISKHRVSQSVFLDDDDPVDAHVSQRIEDVTGLSMEKAEPLLVQNYGIGGRFEPHIDALGEENDRIATFLIYMSDVEEGGATVFIKVGIAVKPEKGSAVFWYNLQKNGESDFNTKHAGCPVLQGNKWVANKWIAEFGQVFRRPCSLHKSE
The following text describes a protein:
Function:
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.
Subcellular Localization:
Secreted.
Sequence:
MARKWNGRAVARALVLATLWLAVSGRPLAQQSQSVSDEDPLFLYGWGKITRLQYLYSAGPYVSNCFLRIRSDGSVDCEEDQNERNLLEFRAVALKTIAIKDVSSVRYLCMSADGKIYGLIRYSEEDCTFREEMDCLGYNQYRSMKHHLHIIFIQAKPREQLQDQKPSNFIPVFHRSFFETGDQLRSKMFSLPLESDSMDPFRMVEDVDHLVKSPSFQK
The following text describes a protein:
Function:
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
Subcellular Localization:
Cytoplasm. Mitochondrion matrix.
Sequence:
MAATFCSGPAASAAANPSSAGRRLQNPAPASVLQARWRPRLPAPAFLTRRPNAELRPLRIAAGAGVDPKVVNGEDFPPMKDLIQLYKTAFLDGNDEVLGEVEKAITSVEKEKSRVASQFESVTAEITSGKEKFIRLNADLENFRKQTEKERAKFTSNIQVEVVQSLLPLVDSFEKTNLENTPETEKEQKISTSYQGIYKQLVETLRYLGVGVVETVGKPFDPSVHEAIAREESSQFKAGIVSHEIRRGFLLKERLLRPATVKVSTGSGKQSASSVEAAKDAAV
The following text describes a protein:
Function:
Involved in the export and assembly of FimA fimbrial subunits across the outer membrane.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MSFHHRVFKLSALSLALFSHLSFASTDSELNLDFLQGMSAIPSVLKSGSDFPAGQYYVDVIVNQENVGKARLSITPQEESANALCLSPEWLKAAGVPVRLEGYASTLNAAGQCYVLSRNPYTRVDFSYGSQSLVFSIPQSFLVGKTDPSRWDYGVPAARLKYSANASQTSGQSTSAYANADLMVNLGRWVLASNMSASRYADGSGEFTARDITLSTAISQVQGDLLLGKSQTRSALFSDFGFYGAALRSNSNMLPWEARGYAPLITGVANSTSRVTISQNGYAVYSKVVPPGPYQLDDVRSVGNGDLVVTVEDASGHKTTTVYPVTTLPTLLRPGEVEYNVAVGRKSSNYKLKKPFADGENGMFWMGSVGYGFDSTTLNAASILHGKYQAGGVSVTQALGGFGAVSAGMNLSQAKYDNGDNKRGHSVSAKYAKSFSDSSDLQLLAYRYQSKGYVEFADFYSTDRYTRYNTKSRYEMRFSQRLGNSNLNLAGWQEDYWWMKGKAIGGDVSLSTTILDGVSVFLNGSYSKRPYLDKPDYSTSLSFSIPFTLGGVRHYSSTGLSYSSSGRMGMNSGVSASPTDRLSYGLNTNLSDKGDRSLSGNLSYGFDAIQTNMMLSQGRDNTTVSGSVSGTILGTADSGLMMTKETGNTLGVARIPGVKGVRINGSAPTNSKGYTVVNLSDYSLNRVSVDMENVPDDLELQTTSFNVVPTEKAVVYREFGAEHVLRYILRVKERDGRILNGGSAQTEQGLDAGFIAGNGVLLMNMLSAPSRVSVERGDGSVCHFSVKGIVPNTGKVQEVYCE
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Subcellular Localization:
Cytoplasm.
Sequence:
MTRPGRPSARKKPDTSRDLLPIRAGIQPEVPVGGQVVELYSDGACDTTKGHGGWATILRYGERELVLSGNEENTTNNRMELRGLLEGLRTLRRPCQVKVITDSQYLRKAFTDGWILNWQRNGWKTASKEPVKNQDLWEELIELAKVHALTFLWVKGHAGHGENERVDELAVLERKKLRK
The following text describes a protein:
Function:
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MENEAKELEKKAEQLNKKGFLASFFGTDNTDEIINCYNLAANKYKLSHKWKEASCCILKNALLHKKNNETSYCANAYLEAGNIAKKYDKLEAIKHIEEAVNMYATIGRFSNCGKCEKNIAEIYEDLYDYDNASKYYKKAAYYFEMDEYSKSIYTQCIVKYAELNSQYNHEYEDAISIFEKEAEKALKSTLLQYGARDYYIKAGILHIVIGDLVNAKISIDKYCMNDPRFLNSREKKFLDNIIDAVTEQNVEEFEEIVHEYDRITKLDNWKVHFLYKIKSKLSVEPNVELTADGNVDLT