lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTIVIGFEGSANKIGIGIIKDGEVLSNPRRTYITPPGQGFLPGETAKHHRSVILTVLQEALDEAGLKAADIDCVAYTKGPGMGAPLVTVAIVARTVAQLWGKPLLGVNHCIGHIEMGRLITNAQNPTVLYVSGGNTQVIAYSERRYRIFGETIDIAVGNCLDRFARVIKISNDPSPGYNIEQMAKKGNKYIELPYTVKGMDVSFSGILSYIEDAAHKMLSTDQCTPEDLCFSLQETVFAMLVEITERAMAHCGSQEVLIVGGVGCNLRLQEMMGVMCKERGARIFATDESFCIDNGAMIAQAGWEMFRSGHVTELPDSWITQRYRTDEVEVTWRD
The following text describes a protein:
Function:
Trans-acting regulatory protein that activates transcription of the CUP1 gene (metallothionein) in response to copper ions. Binds to the CUP1 UAS sequence 5'-GCTTCTTTTCCGCTGA-3'. Binds DNA only in presence of copper or silver. Copper seems to alter the conformation of the protein.
Miscellaneous:
MISCELLANEOUS: Present with 1760 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MVVINGVKYACETCIRGHRAAQCTHTDGPLQMIRRKGRPSTTCGHCKELRRTKNFNPSGGCMCASARRPAVGSKEDETRCRCDEGEPCKCHTKRKSSRKSKGGSCHRRANDEAAHVNGLGIADLDVLLGLNGRSSDVDMTTTLPSLKPPLQNGEIKADSIDNLDLASLDPLEQSPSISMEPVSINETGSAYTTTNTALNDIDIPFSINELNELYKQVSSHNSHSQ
The following text describes a protein:
Function:
Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MGVRGLQGFVGSTCPHICTVVNFKELAEHHRSKYPGCTPTIVVDAMCCLRYWYTPESWICGGQWREYFSALRDFVKTFTAAGIKLIFFFDGMVEQDKRDEWVKRRLKNNREISRIFHYIKSHKEQPGRNMFFIPSGLAVFTRFALKTLGQETLCSLQEADYEVASYGLQHNCLGILGEDTDYLIYDTCPYFSISELCLESLDTVMLCREKLCESLGLCVADLPLLACLLGNDIIPEGMFESFRYKCLSSYTSVKENFDKKGNIILAVSDHISKVLYLYQGEKKLEEILPLGPNKALFYKGMASYLLPGQKSPWFFQKPKGVITLDKQVISTSSDAESREEVPMCSDAESRQEVPMCTGPESRREVPVYTDSEPRQEVPMCSDPEPRQEVPTCTGPESRREVPMCSDPEPRQEVPMCTGPEARQEVPMYTDSEPRQEVPMYTDSEPRQEVPMYTGSEPRQEVPMYTGPESRQEVPMYTGPESRQEVLIRTDPESRQEIMCTGHESKQEVPICTDPISKQEDSMCTHAEINQKLPVATDFEFKLEALMCTNPEIKQEDPTNVGPEVKQQVTMVSDTEILKVARTHHVQAESYLVYNIMSSGEIECSNTLEDELDQALPSQAFIYRPIRQRVYSLLLEDCQDVTSTCLAVKEWFVYPGNPLRHPDLVRPLQMTIPGGTPSLKILWLNQEPEIQVRRLDTLLACFNLSSSREELQAVESPFQALCCLLIYLFVQVDTLCLEDLHAFIAQALCLQGKSTSQLVNLQPDYINPRAVQLGSLLVRGLTTLVLVNSACGFPWKTSDFMPWNVFDGKLFHQKYLQSEKGYAVEVLLEQNRSRLTKFHNLKAVVCKACMKENRRITGRAHWGSHHAGRWGRQGSSYHRTGSGYSRSSQGQPWRDQGPGSRQYEHDQWRRY
The following text describes a protein:
Function:
Transcriptional repressor involved in developmental processes (By similarity). Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes (By similarity). Probably plays a role in limb pattern formation (By similarity). Required for mammary placode induction, involved in maintenance of the mammary buds during development and branching morphogenesis in embryonic and adult glands; partially redundant with TBX2 (By similarity). Involved in modulating early inner ear development, acting independently of, and also redundantly with, TBX2 in different subregions of the developing ear (By similarity). Acts as a negative regulator of PML function in cellular senescence (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEDVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKETGTSDESSSEQAAFNCFAQASSPAVSTVGTSNLKDLCPSEAESDAEAESKEEHGPEACDTAKISTTTAEEPGRDKGSPATRAQLFPAEPSRARDTARLDKASPDSRHSPATISSSTRVPGADEHRSPGREGPVSAKVDEARALPAKDAFAPLSVQTDATAHLTQGPLPGLGFAPGLAGQQFFNGHPLFLHPGQFAMGGAFSSMAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNSMRPRLRYSPYSIPVPVPDSSSLLATALPSMASAAGPLDGKSAVLAASPASVAVDSGSELNSRSSTLSSGSVSLSPKLCSEKEAATSELQSIQRLVSGLEAKPDRSCSGSP
The following text describes a protein:
Function:
Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).
Sequence:
MAEFYSHNDEEVELPSSVQQMINQICKKERQNSPDDTVRRLLVAIGEERSLYILNEISKCQIKKTLSGFIVFMAKKYYQSETQQFYQKQNHEQPVLSAESFYHSPQIRRNSLSSPNSSCSSVNFSPRNRPIFQDRDIVGDTSDSPTSGPRIPSPPLSPVTTSFQKCHYDPSPSKFRDRASTRGISEQLLALNKLEFRKFFLILNYIGRRKVEDVITLHDVGDILDMIYQPMSHFESYIWNKYGHLCEHNKRVQYLDWDSGRTHLYHCHVHSDRSYTFKGPYLKAERTHLQHSLGDENVLIVKFEQNTPGCPEEIVQNGILVGLRRYRFFVYKDDGKKRRLKDKEEKIDSVKCYFVRMESLNPYENETYILHDKMVHEARCNFMHVHMVSSMAKYMARFSLILSTTVKLQVDLNSVNIDRIEDIYCHDKSGRIIYDEDGKPLIHTDGTGYISEDLARKCPQDFFNVKHKCANLVRYANGVKLGENSSELGEAEFQSGEPPLLMQCRLFYNGLAVKGTLLVNRKLPQRTIQIRPSMIKVEADPRLSRAHMFNSLEINTPSLKPRNTYLSRTLIALLTYGGVPVEYFYDILNNTLEETQRLYSDEVTALKVAVNHRDRDDASTATSMIMAGVPLTEPYLWCCLSSLAKEERNGLKGGRLPIADTFYLMGTADPTDTLNRHEVCVILEHGQIFGEVLIYRNPGLHFGDIHRLLAVPVKNLGDIVGNAKYGIFFSTKGPRSAATEIANGDFDGDKYWISQNPQLLKYFTASRPWSRIHSTPKALHREPNNFSAEEREHELFQTFLETRMPNYSMADASANWYALMDRLLILGKNNTIENEETKSVKEKLFELIDLYYDAIDAPKSGNKVYIPKRLKVDKFPHFLQKKESYHSTSVLGEIYDRVEKFKAEEPVAVEIKKLPAFEVGIPETCLRLWEERYRKYRFEMKEALNTSSESKNDLADQVIKKYKQLLYEAPDMEESIRSTTDIYNDALAIYRVTYDYAKAIGDVRKCGFAWKVAGTALCRLHAELHAKEHNQKVMAMSPSILHNLLNLRIHQRSV
The following text describes a protein:
Function:
Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Sequence:
MHTTPLTTMAMQYQAALQILQKTANDMSKRRTRTEELVPLEDSVGRTAAKDILSPDSTPPFDTAAADGFALVSSATINASPMNPVYFRVAGTITAGEKPPLMPPCRGPDGVLQCYEIMVGARFPDTATEHLIHMDACVWATDVQEVSVSEVPKADPQLGNRFIKITKPVTYNANRRRAGEDISKGDRLIRAGMKIRSSHVLPLASVGIKEVAVEPLVRVGVWSTGREIVRSDVDGPTATKRSSTRYTYDADGPYLMAALKEFGAEPHFLGLLPGDDPAVLEKALGETMATDKFDVLVTTGAATPGRSGFVRSVIEKLGGQVHFHGVAMRPGGTAMFASLESTAPNNGLVSFFGLPGDPCAMAASFRFLIVPYLQFVRGEKADEPLMATLELRCSTRQESEPNMDAGAPVEASMGNDCGPLCMDCFRHGRVTASEDGRRKVVRMTKDQGPGKVYPFIEANCWIHLPHGQEIVQGAMVPCLSLSACRDEKWQ
The following text describes a protein:
Function:
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.
Sequence:
MAALLRDPRIPLGASPPAAPRLLLLLLLLPPAQAAPGAHGRPLSKVVALNVNVNVNVACGRRYIQGKIVGGVDVLERKWPWQVSVHYRGFHICGGSIISEYWILSAAHCFDRDKNIVAFDMYVGLVDLRFASNHTQWFEVNKVIVHPTYQLYHPVGGDIALVQLKSRIVFSDSVLPVCIAPPDVNLHNVTCWATGWGLISPQGYVTDHLQEAQMPLISLPLCQLLYGHLSYIMLDMLCAGDIRNVKTVCEGDSGGPLVCELNHTWLQVGIVSWGRGCTYPMYPAVYTRVSYFSKWIHYHIKNTPPPSQPLPALSPMLGATISIPVTMLAVLSTL
The following text describes a protein:
Function:
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Sequence:
MQRAITLFSLLICMGITLTGCIYRPPVQQGNVITDKDLGALHKGMTKTKVESLLGTPVLTNMYADNRLVYVYIFKKGHHKMHSTRLIVYLRDNRVVSFWTDKINPATGLSCLTPNHSPNFTAFSPQ
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.
Subcellular Localization:
Cell membrane. Cytoplasm.
Sequence:
MTIMSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDDLYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQAYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGTVIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAPGNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHSTGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK
The following text describes a protein:
Function:
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MIAQLPRFHPALFSVGLPESIIAAACSRSGQRVLHVDSRNYYGGNWASFSFSGLLSWLKEFQEKSNRGEERAGWQDLLLETEEAIALNQKDETIQHAEVFCYASQDPEEEVEEAGALQKNPAYGAPLNSAAAQGPPSPPEEGPSPETESREAAEESRVEERPPEDGCSGEAAPARPAPSGDAPPEENRTRRPRSSPITYSQIVRERETSPLRLHWFAIFPSSVRCPLDTPPLKHVSVLFIQLLYSRGPLIDLLIKSNVSRYAEFKNVTRILTFRDGRVEQVPCSRADVFNSKQLTMVEKRMLMKFLTFCSDYEQHPEEYRAYEGRTFSDYLKTQKLTPNLQHFILHSIAMTSEAATPTLEGLRATKNFLQCLGRYGNTPFLFPLYGQGEIPQCFCRMCAVFGGIYCLRHSVQCLVVDRESGKCKAVIDHFGQRINADYFIVEDSYLPEKSCSPVQYGQISRAVLITDRSVMKAESDQQISILTVPPEEAGHPAVRVIELCSSTMTCMKGTHLVHLTCTSSGTAREDLEPVVQKLFRPYDETEPGNEDADKPGILWALYFNMRDSSGIARDSYTDLPSNVYVCSGPSGALGSDHAVKQAESLFQHLLPNEEFCPPPPNPEDIVFDGAGSQPEDPGFDHPSTPESETPEGGPGPEGGQEGEGSKLPEE
The following text describes a protein:
Function:
Required for the correct synaptic targeting of motoneurons RP5 and V to muscle 12 (M12). May be involved in the negative regulation of Tl in M12. Involved in the correct patterning of veins in the proximal (costal) region of the wing blade.
Subcellular Localization:
Nucleus.
Sequence:
MESNAFGSSHLPSQALVVLSEAASGLHEALRGQRPFPSRVIPFDFPLLQLPDAKDLHNMSLVGNYFNPHLLLNHGMLVANGAAAAAAAAGAGPASYFASDRSPLGKPSVLSNFSLPSAFSPPKYIGISLDQNLFNGSESFRTDSASPTCTSHESMEGSQDYDAVEKGESPRSNNSQDPRDLRHLHNAGKSHQALATSSSASSSSSSSCSTSNPAISTATSSVAVSMASHLAASSPHHHPHTHAHSHPHPLAHPHAHSHHHVGHHVGAPPVSTAVTTHHHMAHPHPLSHHHAAHHAALASLSMAGLRAVPGGLSLVSGLQAAAAGGAIPEMCPVCGLKLSAEEWHTHFLTELDRLYKLSAGFERASLQATYMFAPPCPAQENAIRTSHNRWETFQRIRNNRQNRLRLKVRKRKYGEMYMMESLYCSSCPICKRKYALETGKIPPEDDAKSQEEIETVDVESCNDEVPDSGSELATPSSGSSGTVMPPSSMHNSNSQPGKLDGILYRTGCVLSQKDPHPDEHDVSTNVTTASSSSWPGEAPTQAHISVKTVSELSSTTHHYYNADSCGVGVNDTNSSSSTHNNGGGSNKDLMMDTASCQNDSDEDVIVDDDDTVKLTSKINYGKIQRRQDEQNVGSSRSLENISPVEERPRSEPQVSSTEPGPMDISHNNNNNNNNNNNNSNSNNNNNPSTKYAESMENSLSQLSSMGVPGLTQLDTKA
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLANYALIGIFLVAAISFPLIPLVLAFFLRPKRPTPLKTSTYECGLEAIGDVHVQFKVQYYLYALAFVIFDIEVIFLYPWAVAFNAVGLYGLIAATIFLLMLFAGLLYEWRKGALEWV
The following text describes a protein:
Function:
Involved in the malolactic fermentation (MLF) of wine, which results in a natural decrease in acidity and favorable changes in wine flavors. Catalyzes the decarboxylation of L-malate to L-lactate. It can also use pyruvate as substrate.
Sequence:
MTDPVSILNDPFINKGTAFTEAEREELGLNGLLPAKVQALQEQVDQTYAQFQSKVSNLEKRLFLMEIFNTNHVLFYKLFSQHVVEFMPIVYDPTIADTIENYSELFVEPQGAAFLDINHPENIQSTLKNAANGRDIKLLVVSDAEGILGIGDWGVQGVDIAVGKLMVYTVAAGIDPSTVLAVVIDAGTNNEKLLKDPMYLGNKFNRVRGDKYYDFIDKFVNHAESLFPNLYLHWEDFGRSNASNILNSYKDKIATFNDDIQGTGIVVLAGVLGALKISGQKLTDQTYMSFGAGTAGMGIVKQLHEEMVEQGLSDEEAKKHFFLVDKQGLLFDDDPDLTPEQKPFAAKRSDFKNANQLTNLQAAVEAVHPTILVGTSTHPNSFTEEIVKDMSGYTERPIIFPISNPTKLAEAKAEDVLKWSNGKALIGTGVPVDDIEYEGNAYQIGQANNALIYPGLGFGAIAAQSKLLTPEMISAAAHSLGGIVDTTKVGAAVLPPVSKLADFSRTVAVAVAKKAVEQGLNRQPIDDVEKAVDDLKWDPKY
The following text describes a protein:
Function:
Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Subcellular Localization:
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus.
Sequence:
MFTQFSTTAENFSKASTMVFRIGTDAHLYDDPDDVSISPLLDSKFDSEKCEALKRLLALIAQGLDVSNYFPQVVKNVASQSLEVKKLVYLYLLHYAERRPNEALLSINIFQRDLGDQNPLVRAWALRTMAGIRLHVISPLVLVAVRKCARDPSVYVRKCAANALPKLHDLRLEENASAIIEIIGILLNDNSPGVVGAAAAAFASICPTNLPLIGRNYKRLCEILPDVEEWGQIILIGILLRYVSARHGLAKESIMSSLLPNIFSNEKSSESDTDYFEIKKTYEIGIQDPELVATVSRSYLAGPDKQLLNLNDSDVISPDYISSRFTSSKSDENVKLLLQCTSPLLWSRNSAVVLAAAGVHWIMAPMEEISKIVKPLLFLLRSSDASKYVVLCNIQVFAKVMPSLFAPNVEDFFISSSDAYQVKALKLEILSSIATDASISVIFQEFQDYVRDPDRRFAADTVAAIGLCAKRNPQVANTCVEGLLALTSPKTVNSTSGSMDDEAVVLIQAITSIKDIVKQDPLSHENAIIILIRNLDAIKVPVARAMIVWIAGEYNSIGNIIPKMVPVILRFLARGFPSESIETKYQILNAAVKVLLNSKEEDFHTAKSILNYVLELAKFDLNYDVRDRARVLRKLLSCYFSSSGPDEKPDNNEIRLLLAEHVFGDKTKPSTKTVNNRFYLPGSLSQIVFHAAPGYEPLPEPCSLTESDMVKGLEEPAQAEADDSDVDSGSLNEEGSYYSEDSVTTSTGTNNESAASESNNNDNTTDPLINFSDVGKPHEGTNDLSELMSKGALESWLDDNDSDNDNRGSSQNVAERIPSARISIGDISTITKPKVYTLLDPTYGNGLKVVYKYSSEASTISPSLVSVDTFFENCSSDPMSKLSMSNEDSESSDQGSSLGSQKDEPAFVPMEEITVLEPGQTVKRVIHVHFPHHLLPLKLILWCNDKKHPVKLRPDIGYFIKPLMMDLDVFSQKESQLPGMFEYTRRCSFTDHLAEVASDDKDGDVSSTKDSFLIICQCLASKMLSNANLHLVSVNMPVDANLNDVSGLCLRFSGEILSNSIPCLVSVTLDGKCFEPLNASVKVNCEETVFGLNLLNRIVNFLAEPRLTS
The following text describes a protein:
Function:
Participates in the second step of pre-mRNA splicing.
Subcellular Localization:
Nucleus speckle.
Sequence:
MDILKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKPINEKPSGEIQPKEEDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQVSSLESRELPWK
The following text describes a protein:
Function:
Putative RNA exonuclease which protects neurons from the toxic effects of expanded poly-Q disease proteins. It is unknown whether this is via participation in the pathogenic mechanism underlying poly-Q-induced neurodegeneration or if it is by acting as a genetic modifier of the age of onset or progression of neurodegeneration. Regulates gene expression in neurons.
Subcellular Localization:
[Isoform a]: Nucleus. Note=Forms aggregates in the nucleus.
Domain:
The Gln/Pro-rich N-terminus and the Arg/Asp/Glu/Lys-rich charged domain are critical in protecting glutamatergic ASH sensory neurons from degeneration. ASH neurons expressing isoforms lacking these domains show progressive degeneration.
Sequence:
MFNGGYGSGNSFNLQNYAPIDPMTGIPGFGPSQNAQQQQQQASAPGTSSGGPSQAVSGASSGASMKTEPVARQVSTAQMKRDLEQAAVYVPTPIPEGSTQPQQRQQQQSQPQARQMSTQQAANLRKNAAAAGTPPKQAMQGASREQGNAHQPTAGQIPQSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQVQNAPQRIPQHVPMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQTPARGRPANAQLAQNAQQRNPQQVPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAPVQGPHRGAPQMAQQPGPHGAAQHPSSGTVAPMHITSLPGNHPLNRTHLLFNRQVVPALDIRNLIAQHRLMVDDFVRAQICYRLPENHQDYWPPGGHPIPMQQQQMRQGAGLPNMAMPPPPLMRHPGPHQNPIHAMQSMQVQPPLSPDQMNMQMFQQRALMMQQQAMQMQMQNPPPVHQQPPPQQPPQQQRQKQQRSQPAPARVPPQVPSQVPVTGGVAADEPPPPCSYSPVAQSSESKIEPVDVKPRVAPVPPQVPVTPTKPVITNNKKKRIDVVTLDEDAPRRVQVKQEIPEVSSTSDATKSDAAPTARGAVRIKQEVESDVAPNTILISAKKFERMKAEAEDKEDMKKKIAALQEALFNIQEERRVEKEIAAFATTNQAVPQNQPASSVQIAQVSTSESDAPGTSEAAATETMTSPKTKNNVIVETEGEQEEDEDEIPIKKSKKRRAKIVSNDEEEEPVRHPKRRSDEKREKRHVSYAESDDDMPVVKKKRRNQSPEDPEYSAASPSEDEDDDIGSFVVSDNEDDDADSFVVGDDEPIEYEEEDEDDMIERRSSRKRRSDSRSKKSATPTDRRRSRDTPTGSRSMRSTSPNDRRKSRETPPGNRSMRRTSPSDGRKSRDTPTASSSMSSSTLSYCKKSKETPMSYEEIEQQKKAKRQRNCKTREENRERKRLAQLEELESSETTGVRRTLRSTQDNSDPLDASLATTIEEFRKTKKKDAKSSENRAKEKQKPMNKRPTSSASVDSNDDGVHIPAKRMAHASSVPGPSRSKPPMIGAVKNRPNHTEMLDKRNKESEEKRRKDRDELERLRNKKHTTEEEKIKMARLQNALKVVGKAAGLKATVKKELTGSPAKKQKPAPAVPKILDFSVGRTFTAIRQTAIKLVFDTFLERDSPNAAREAQEFELSIAKQYTDGQKYRINIGHKVAALRKENTSGILEVNKNAVSHDKILAGGPKDNCTVARGRKTHVDHRQLSIEKLHPLLLQFKLTTSELETNAYPMRRDGSTKAVSIADTVYTQNKKMFLDDYDMSRNCSRCNKEFKLSPNGTMIRSTGICRYHNRGVAINGKRDTFRKRYSCCNEEFNVALGCKFSDVHVTDQLFKKELSTFVSTPVPVPNDQRSTRVYALDCEMVYTIAGPALARLTMVDMQRNRVLDVFVKPPTDVLDPNTEFSGLTMEQINSAPDTLKTCHQKLFKYVNADTILIGHSLESDLKAMRVVHKNVIDTAILFRSTRDTKVALKVLSAKLLHKNIQGDNEDAIGHDSMEDALTCVDLIFYGLRNPESIAIREANTNC
The following text describes a protein:
Function:
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
DYGIWERGDKTNHGLPELNSSSIGMAKAALQALDDLDLFGGKGGPFSVIHVLADEAQKCNAVLQSMLPRESNSKEVDAALLSVIGYPAFAVDDLDLITLTRESILQKLRGKYGCKRFLRDGYKTAKEDPTRLYYESWELQHFENIECEWPLFFCYLVIDACFRGERLEVEEYSDALEQLLLRTEDGLKLVPEMYAVPPDKVEAEYKAPHSQQRVHVGMTPFMWAQSLFIIGRLLQEGFIVPGELDPLNRRLASEKKPDVVVQVVVLAEDHIIQEKLMHHEIFVQTIQDVPDFEVLPARVLGHIYTYLGRSSKLNLSGRQSRDVGILSTSKMYLFKDSLLVFTPQRFDMGRLPRTLYFFFQRMFLEHLKFLFFSENGKIPGEIIATIKKLKSGYTTGTRYVRGQNFARFQSSSNTPVKFFCVPAELRDYLNKEFSRKDLRRDSIFLRRQSICPKSPAVHGTSHRKLGVSGVVRRSRSIYADNFFSFEQPALPKDTLPSLQEGQSQGYGDSPSPAYDSDEEELCEVVDVPGKSSLGLSDLQLGNISEKELVDLLEESDSLEEHGDILHCLVLNKGLKWDTELGDGGQVITVRHLLKELYEKAYKERKWGLVRHVAGLLGKKVEDLAKAVTDLLVRQKQVTVGMPPMNEYTITRPQPAKQLRIIIYKTYGGDKSAVMLTQELLVYLSMFIRTEPELFQEMLRLRVGLIIQVMVSELSRSIKCSANEASEYLLNMRPYEMKMLLRQILSGKEFVICHTQQHTMRRDITSTKKSDDSFDRQGQWIRRRRLDGALNRVPMGFYPKVWKLLERCVGLSIEGKVLSQHLTREMTSGELKFALEVEHVLNSIPQPEFRQLNVEAMMVLTLLAEHNVVTFINKVINVDELVRSAYKMFLEDQKRCKGDSTLCCANDGNTPSKTNCNKVANICEHFYDSAPSGCYGTMTYLIKAVAQNVEDLPNTSLDCTIS
The following text describes a protein:
Function:
Role in flagellar biosynthesis.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Sequence:
MLDFIQELSTPHVRDFFLLFLRVSGVLSFFPFFENHLVPLSVRGALSLYVSAIFYPTLEFSNAAYTPEGFIIACLCELFLGVCASVFLQIVFASLVFATDSISFSMGLTMASAYDPISGSQKPIVGQALLLLAILILLDLSFHHQIILFVDHSLKAVPLGQFVFEPALAKNIVKAFSHLFVIGFSMAFPILCLVLLSDIIFGMIMKTHPQFNLLAIGFPVKIAIGFVGIILIASAIMGRFKEEISLAFSAISKIF
The following text describes a protein:
Function:
This protein inhibits elastase and trypsin simultaneously and independently.
Miscellaneous:
MISCELLANEOUS: Two forms of the inhibitor were isolated. The shorter form is probably derived by proteolytic degradation.
Sequence:
MMVLKVCLLLVFLAGVTTARMDLNHLIGSNHHDSSDEPSESSEPCCDICVCTASIPPICQCTDVRLNSCHSACKSCMCTRSMPGKCRCLDTTDYCYKSCKSSGEDDD
The following text describes a protein:
Function:
Plays an important role in the synthesis of 18S rRNA but is not required for the 5.8S and 25S pathway. Is necessary for the cleavage at site A2. Is required for efficient association of RPS27 with the pre-ribosomal particle.
Miscellaneous:
MISCELLANEOUS: Present with 2610 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MGIEDISAMKNGFIVVPFKLPDHKALPKSQEASLHFMFAKRHQSSNSNESDCLFLVNLPLLSNIEHMKKFVGQLCGKYDTVSHVEELLYNDEFGLHEVDLSALTSDLMSSTDVNEKRYTPRNTALLKFVDAASINNCWNALKKYSNLHAKHPNELFEWTYTTPSFTTFVNFYKPLDIDYLKEDIHTHMAIFEQREAQAQEDVQSSIVDEDGFTLVVGKNTKSLNSIRKKILNKNPLSKHENKAKPISNIDKKAKKDFYRFQVRERKKQEINQLLSKFKEDQERIKVMKAKRKFNPYT
The following text describes a protein:
Function:
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Sequence:
MEHPALGTLWLPSTKIPRPQFLPAHRIPLTNSPQSFPCKMSQFSAIPVSRQASMSDFWLEVEHIKQSRRSDVDECNSSDSGITEDGEAEAAWLQDTGLSTLIGDQSPLETNIIISTLTQTQAAAVRRRLDTYSYSLRERWKQPTRDVRDVFIAKGSADGFFRKNGKVHTSDPKQALGRVLTLPYKGSESQHRVPGGANIFDTDVAYSEQAATMQKEEQARVQDTGTLPKFQLHKGRLGTTCVSDLNPSDMKQVPALALIELTALCDILDLELKRNKAQKRKSAESHLFGVTLPSLLIKDQKLVPDTKVPLILQEIFACIEKNGIEVEGILRISGSQARIKNLQQRLDKDFYDGLFSWDDVHPHDASGLLKVFLRDLPAPLLTTQYLPAFTAVQNIPDLKQRLQALNLLILILPEPNRSTLKALLEFLQKVAAREKTNLMSLWNVSTILAPNLFLYHGGKNLNRGEKQIAEGTAALVMAMVHYQDLLWTVPTFLVSQVRKLNESGTKKHAFRDRRLRNFLRKIHTDKERSEKKQTELCKQVKIQSSLWLKETMAVRVDGGTQASDVFEQLKKLGQRSWDMASTVCFLRSSSEYPNLALFEVGGNLCERRLDPDTYLMDLYNANPNAEWVIKSSS
The following text describes a protein:
Function:
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
Subcellular Localization:
Cytoplasm.
Sequence:
MSEEKQTVEQNETEEQEIIEEQAAADEQQEETNESELLQNQINELQGLLEEKENKLLRVQADFENYKRRSRLEMEASQKYRSQNIVTDLLPALDSFERALQVEADNEQTKSLLQGMEMVHRQLVEALKKEGVEAIEAVGQEFDPNLHQAVMQAEDENYGSNIVVEEMQKGYKLKDRVIRPSMVKVNQ
The following text describes a protein:
Function:
Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
Sequence:
MAAAIDDVTVDKDCSENDEDQIEDQIEEQIEDQVEEKSEGNKNQGSELNGIECEVDHLNIASNNSAHGDSLNSRNTGKNDNLAQFGIPQYCWTVQLNHKFSEKWRPLTMVRPHQIKSFVLPSVRYAQMHLKMWRGGKRPFIDVLHPMKFKPVYGVPVGGIGCGAIDRGWKGDFCRWSLSPGRYTYDNVELNQFTVCVRRGGKTVYQQVLSPNKPHNKDLAQAWEWQFPGNRASYHGLYPRAWTKYLLPGQNITLVCRQISPVFPHNYQETSLPVGVFVWDVYNHGTAAADVSIMFTWKNGTGTSADKKGGRWNTGFSSASTSGVMFHDGHPTQPCTMCIAAADGDDVTVTTCASFNPSSQLKELWNDLKEDGQLNTTKGPTERTEKGETLAGAVVSSRHIEPNQQGLLEFALSWDMPKVQFDSCSYFRRYTRWFGRDGDSALALCSHALEEYGDWEKNINEWQNPVLENDRLPAWYKSALFNELYFMTDGGGIWVDVDEEYPNGENNAHTRASSLVREYGRFGYLEGHEYRMYNTYDVHFYASFALIMLWPKLELSMQYDFGQYVDHKDEDSFQDLSSGLRSIRKSAGCVPHDSGNPEEDPWLKLNCYWFHDTAEWKDLNLKMVLMVYRDYFATKDREFLDFMWPKCMTVMAKANSQDKDGDGLIDHFGTADQTYDVWTAKGCSAYCGGLYLAALKCMCEMADLLGDDKAKRQYSEILQRGKATYEKKLWNGRYFNYDSSDQSYHDSIMADQTCGHWYLRACDLVPERDQVFQVDHVRSALRTIFDMNVMGVKEGNFGAMNGIRPSGKPDHTSLQGEEVWVGTTYGLAGNMIQEGMWEEGFRTAKGCYTTCYEQAGLAYQVPEAYMSKKIYRSLGYMRPLAIWAMQWAVEKRQQQEQEQAPSS
The following text describes a protein:
Function:
May be a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death.
Sequence:
MAGKLRLGQQGGGRWGLGEAGCGGREGAVRAPTPNPPPPLPREIPAEAEAEAEAEAEAEAGPGVEAATGPGPGPGPEPGPGAALALQLGELELKEEWQDEEFPRPLPEETSTAPPDPRLVGRRPAGPRSTLALCGRRPMRKRLSAPELRLSLGPGGRPGGGSRTPGPAASPSPSSGGSSSSSDLRLDELETPSDSEQLDGGHDFDWEDELPRAGSELGVSAAAERLGRGCVWDMAGSDGRHWRVFRMGEREQRVDMSVIEPYKKVLSHGGYHGDGLNAVILFASCYLPRSSIPDYPYVMEQLFRYIVGTLELLVAENYLLVYLSGATARGQVPSLAWIRQCYRTLDRRLRKNLRALVVVHATWYVKAMLALLRPFISSKFSRKIRFLGSLRELEQLVSLEHAHIPDPVRQLDQDLHGPTDAQD
The following text describes a protein:
Function:
Required for activation of most nif operons, which are directly involved in nitrogen fixation.
Sequence:
MATILDDRSVNLELVTIYEISKILGSSLDLSKTLREVLNVLSAHLETKRVLLSLMQDSGELQLVSAIGLSYEEFQSGRYRVGEGITGKIFQTETPIVVRDLAQEPLFLARTSPRQSQDGEVISFVGVPIKAAREMLGVLCVFRDGQSPSRSVDHEVRLLTMVANLIGQTVRLYRSVAAERQQLQEEKRQLSRQLQGKYKLDNVIGISKAMQEVFAQVHQSAPSRSTMLLRGESGTGKEVIARAIHYLSPRKDGPFIKVNCAALSETLLESELFGHEKGAFTGAQGERKGRFELAHGGTLFLDEIGEISPAFQAKLLRVLQEREFERVGGSRSIKVDVRLVTATNRDLEKAVAKGEFRADLYYRINVVSIFIPPLRERREDIPYLVEHFLEKFRVENQRAMVAMSPQAMKVMMNCYWPGNVRELENCVERTATMMRGDLITEVHFSCQQNKCLTKVLHEPGQQQPVVVVPLERISAPYGAIFAEWDGQGQATGAAPPTSERERLIWAMEQCGWVQAKAARALNISPRQMGYALQKFNIEVKKF
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
Sequence:
MNGIIPLWKERGMTSHDCVYKLRKILHTKKVGHTGTLDPEVEGVLPICIGRATKLAEYVTDEGKVYVAEITLGKSTTTEDATGETVNTKELAEISAAELQAALTKLTGKITQIPPMFSAVKVNGKKLYEYARAGIEVERPSRQVDIYSLIRLDGDTALNQSNPTFQLEIACGKGTYIRTLAVMIGELLGYPAHMSKLERTRSGFFKKEDCLTLTEIDEMMQASDSSFLYPLEKGIESMAKLVIEEEVYAKVLNGGLLPTSLFAEVENEPRAALIFKDKLTAIYKPHPEKKDLWKPEKVIELNQA