lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Odorant receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLTNGSIVTEFILVGFQQSSTSTRALLFALFLALYSLTMAMNGLIIFITSWTDPKFNSPMYFFLGHLSLLNVCFITTTIPQMLIHLVVRDHTVSFVCCMTQMYFVFCVGVAKCILLAFMAYDRYVAICYPLNYVQIISQKVCVSPHSDWPLLWGPSGNLCRCHRGNSQPHGAHCHFLCAHPGHHPQQKASSSSRGKTFSTCASHLTVVIFLYTSAMFSYMNPHSTHGPDKDKPFSLLYTIITPMCNPIIYSFRNKEIKEAMVRALGRTRLAQP
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. uS17m may have a meiosis-specific role as it accumulates during the middle stage of sporulation.
Subcellular Localization:
Mitochondrion.
Sequence:
MKLNYVGIVISRAMPKTAKVRVAKEKFHPVVKKYVTQYQNYMVQDDLNCNVGDAVTIQPCRPRSATKRFEIIKILSTANRMSPASEISKE
The following text describes a protein:
Function:
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Sequence:
MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVADENITVATVPGALEIPIALMNFASSEKFDALIAIGVVIRGETYHFELVSNESGAGVSRVALDYNIPIANAVLTTENDAQAIERIEEKASDAAKVAVECANLVNLLLEEQFEDEE
The following text describes a protein:
Function:
Required for endocytosis. Also involved in cytokinesis and cell division.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle. Nucleus. Golgi apparatus. Note=Localizes to endocytotic vesicles.
Sequence:
MSLASLPLEKLTKVADVDKRETIYIDLLNYEKQLRNLNKNTREDSLQTNLNPLLSLIKKYGNFIAYPTRKLLSNCIIALLKGLEGYHQHRVLLYFVDSIHEKKDYIEIINVLSVLTSCLEEYGNQINQQETFIRFFFKYSKTNLSYGVRSIALDGLSKCIETSIQSTNEDLIKEIWKCIKSNLNTSSTNVLLSALRCAYYILGSSRLRNSELEWFKSFLFKKSSIDNSLLHSSLGRCFSALASAQADKSIEAAANAVPSTPADDENNEEVENRSTTRRFDETESFRHALRILVENYHSKHAKYESSKAVLVFAVKHLFLMQRPSFVSLNYTTIVDIILLHQSHSTSKEWLSSLEQYHCTYLFRDVIGRRFLDQSSELQGIEILLKRVLEPYLKDQSKISEIAVKTAMASTADILSRSKGSATALYSQLLDTTLQILYLGKDSLKNEVAWLLRCLLSVMPSPLMPTLLALFNRLELEFKHLRSKPKEVSPKLNVGIFNNLTLSLMSIYVAAEENPLYVASSIFSKLFNFSLDLIKSSSKLDLLAAQAQIKTGWRLLSAYVSFGPSFTRMQLSQLLILWKNALSRVPSKIHSQNFMETNADMFNRFEALQCLLSFLEYNKILFTPDVRKRVIIFLNNCLKFYKAFSLTKRLEITMPIPASDYSHLELRSLLLARIFQCFFELSQLSGMSLDDQELLSTTVSTIAELSSLQGYDTADEIVQAKAFTSPRVIPGIGSRFYAQPEEEFQTTMDDILPCYICESSSDSLSVISRSNSAKLPYVPPSLTSLIDNAIQLFASMFCHQPPKVMESTLEIMVASVTNLKSGRDILRYKAVTANTLFSIYGFLSAFDNKKVTLPDKVVSLMIELLENLTAVNDPKLIPYISKSYAFLAYLYQSKPTSVLDTIIKRAAESGDPNCRAVLILAVGHILKKVGSGVPQTTLITAYQLLKVFNTDSNDLVRECSIRASSVSLGSIAKTIPSVLTAQTRILLSYMLLPECDIDVQLLKKRNSLFFPSTLFANYLDCLINELGPNLRSDSSTSHFAFDLAHQLLLLSRDTGDNIIHVYKCYQHLYLFTPLETNSDFFIRELCGNIIDLKQPKRREISIEVLYQILLQNHEFSESCYKRHFDRLIWQSLDTTPDNKLLKNILYIWLNDYKDSDIHSWVNILLFLVGIKNTSSSERSNEQDIQNNLDEDTVSLAYGTSENASNPLFQKNYRWQTQFYAATCLKTCISEVMAENKEPAKYLISRISDLVRAAFVLSTSDNFYLKQGGFELLDTIITDFSNVMDPDFDDVSLLDQFQAQISSAFSSAFVDDSSPEIVAMSLNIASNFIGTGLLKTESQAAKILNLLKEALESSLPERAGFEENRHFKYDSKYFLRIATLSAWASLLVHSANVSYLKEFLSSNIRRLSSHWIMALRGYSRLQFGPSLVKDFVADTSFTRVQSINPKILLNIYEKSWLNIAESLTILLSTDANLIYGILSGDELSLSEEDVFFQDNINYASNRYSFNFFLFSVCFQSLLIPSTLQGFRNPVFRIMRIMTEVLTEELCTKVLYDHNVFPEVVDLLVRLILTEDWETKASIVIFVKKLALANPAHNDLKFCETDSVTSMEPTVSESVEMLFQLVKILTLALTVRVPGLRSDPAESATNKKASEFVILCFNAFLDVSNIFPAIVRVDLFATAMHVYEVIMDDQQLLKNSKQELLAALRKLLSTMVEQNDHTCTTLIYTLFEHLLNIYKETINDSDKKEKNETAFMSMVLVLTLAAPILDSEQLVVHDFLEELFSSLKSSEEDFALRTRCVTSLMLVNSKHPSMSALCRFIIYKSVTMLQNGEVLKSGDYVTEFIPALLDMHVHIPEEKKKSFLSMSIPIAAHFSILVEHADARKRIGEKLLKIMAIQPDEAKAIIQQLSPRQKKCVEEILIQNVE
The following text describes a protein:
Function:
Acts as a negative regulator of abscisic acid (ABA) signaling during germination and early seedling development.
Miscellaneous:
MISCELLANEOUS: Seeds over-expressing ZFP4 are insensitive to inhibition of germination by abscisic acid (ABA).
Subcellular Localization:
Nucleus.
Sequence:
MRPILDLEIEASSGSSSSQVASNLSPVGEDYKPISLNLSLSFNNNNNNNLDLESSSLTLPLSSTSESSNPEQQQQQQPSVSKRVFSCNYCQRKFYSSQALGGHQNAHKRERTLAKRAMRMGLAGVFPGRGSSSNYAAAATAAALSCLPLHGSGNGNMTSFRTLGIRAHSSAHDVSMTRQTPETLIRNIARFNQGYFGNCIPFYVEDDEAEMLWPGSFRQATNAVAVEAGNDNLGERKMDFLDVKQAMDMESSLPDLTLKL
The following text describes a protein:
Function:
Plays a role in differentiation.
Miscellaneous:
MISCELLANEOUS: Overexpression rather impaired the progression of differentiation. Antisense RNA-mediated dia1 inactivation was found to enhance the initial step of cell differentiation.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MKFKLFLLVFFVFLLPYLSQSCENTFSCPTLNQTCTGQCSAGLVCNQTLSSCQEYEKCDSSLPLAEDTCSQDGYICVSNVCLPFIGTQYPSSQCKQNSNCLMSLCAGNICMVMPGSQCQTNSQCSPDQFCSTTFIGTTSTSPSTMTLPMTMTLPMTMTLPITMTMGSSSVCTNRLQLNSQCSTSDSCQTGLACINSVCSPIFSGAENATCFPGAIEPTKAACDVGLSCLNGANGYSCKSYVENQSCDPSDEYPVCNSDYQSCKCNSKGKGSCQSYYKLTQECKDSSNKLVLCAKSKNSIPSYKDYVTQINCQSQLCNYSRDCIDPKAKVSTCFNDLFLMCPSDYQEPEIGSSSSSSSSSSSSGSSSNSTSSSTSSTSSTSSESSESSNGSNSNSVSSESSSPSSSSVESSSNSKSNHTSSESSSSDDDLGNPSSSSILSVSKLIILLISIILYCF
The following text describes a protein:
Function:
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Subcellular Localization:
Cytoplasm.
Sequence:
MAASTEIETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFEGLTDKSKMETQPELFIHIVPDKINNTLTIIDSGIGMSKSDLVNNLGTIARSGTKEFMEAIAAGADVSMIGQFGVGFYSAYLVCEKVIVITKHNDDEQYIWESQAGGSFTVTRDRSDEKLGRGTKMILFLKEDQLEFLEERRLKDLIKKHSEFISYPISIWIEKTSEKEISDDEDEDEVEKKEEEGKIEEIDDEKNEKKKKTIKEVSHEWSLVNKQKPIWMRKPEEITNDEYGAFYKSLTNDWEEHLAVKHFSVEGQLEFKAVLFVPKRAPFDLFDTKKKPNNIKLYVRRVFIMDNCEEIIPEYLSFVKGIVDSEDLPLNISRETLQQNKILKVIRKNLVKKCIELFFEIAENKEDYTKFYEAFSKNLKLGIHEDSGNKDKLSQLLRYYSTKSCDEMTSLKDYVTRMKDGQSNIYYITGESKKAVENSPFLEKLKKKGYEVLFMVDAIDEYATGQLKEFEGKKLVSATKEGLKLDESEDEKKNAEKLKEKFEDLCKVIKDVLGDRVEKVVVSDRVVDSPFCLVTG
The following text describes a protein:
Function:
Acts on leucine, isoleucine and valine.
Sequence:
MQMSDLLIYLNGKFVPKDEAKVSVYDHGFLYGDGVFEGIRAYNGRVFKLKEHVDRLYDSAKAIAMDIPVTREEMTEIILEALRKNNLKDAYIRPIVSRGIGDLGLDPRKCGKPSVIVIAQGWGAMYGDLYEVGLTGVSVCVRRNAPDALSPNIKSLNYLNNILAKIEANEKGGDEAIFLDHNGFVCEGSGDNIFVVKDDRVLTPFTISNLKGITRATAIELLDEMGYKVIESNLGLFDLYTADEIFVTGTAAESAPVTRLDGRVIGTGKPGPLTMKMVEAFAKITQSTGTQIYK
The following text describes a protein:
Function:
Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Single-pass type II membrane protein; Intermembrane side.
Domain:
The CHCH domain contains a conserved twin Cys-X(9)-Cys motif which is required for import and stability of MIA40 in mitochondria.
Sequence:
MFAKNLLFRFPKCIRINGYNNMRRSLLQRNGFQAGICRKFGTATKTDVWKGRFLPIVSGVAAASLTAGYLLGKNTSNASSSQDNDHPVVGEHVHTETQSYNEPYMQRHRIEDAIEKKMTSETQPSTDEKGRKVSATENSAPKKTDKEKSSGETAGNILREQIATGKDDDEYARKFEEVEEESSEESAFNPDTGEINWDCPCLGGMAHGPCGEEFKAAFSCFVYSKSEPKGMECLDKFQAMQACFQKHPEIYQDMVGESEEEDAETNEKPSTTSDENNQPQSPPSDNASNPEEDVMNMEKEIVNLTPMSVIKEI
The following text describes a protein:
Function:
Has significant hemichannel activity. However, has only low-efficiency gap junction activity and probably does not function as a gap junction channel in vivo.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSLNYIKNFYEGCLRPPTVIGQFHTLFFGSVRTFFLGVLGFAVYGNEALHFSCDPDKRELNLYCYNQFRPITPQVFWALQLVTVLVPGAVFHLYAACKNIDQEEILHRPMSTVFYIISVLLRIILEVLAFWLQSHLFGFLVDPIFMCDVTGLGKILNVSKCMVPEHFEKTIFLSAMYTFTIITILLCIAEIFEILFRRLGYLNQPMT
The following text describes a protein:
Function:
Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.
Sequence:
MGYAQLVIGPAGSGKSTYCSSLYEHCETVGRTMNVVNLDPAAEIFNYPVAMDIRELVSLEDVMEELGLGPNGALMYCMEYLEDSLHDWVDEELDNYRDDDYLIFDCPGQIELFTHVPVLKNFVAHLQQKNFNVCVVYLLDSQQFITDVTKFISGCMSSLSAMIQLELPHINILSKMDLLQDKSNIDTYLDPEPRTLLAELNQKMGPRYAKLNKALIEMVGEYGMVNFIPLDIRKERSIQYVLSQIDVCIQFGEDADVKIKDEDEDFGDDQ
The following text describes a protein:
Function:
Probable ion channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MPKSGAHQPLVRHDTDDGGETGQSVKSLADVSEEEIDSRMSRRSSVIADLLSLFRRSSSVLVRPHTRLGNPNFDDDDDEFDEEDDKEASKDRILKKIQQKKEIIQKLRGQPWYMKRKRRTLKVAQKHLQQQEAKVSKARLYKAEAGRRLTQASRWLDNLKIYLIPWEAKIRKIESHFGSVVSSYFTFHRWVLGVNITITFIMCMFVVIPEWLADSRTQFGDDRYNKTKAIKVMPPAVRARADELSTVWDFGGYFQYSLLFYGFYSKETFFGETIKYRVPVAYFFCNIFILGFSLFIILRKMAANNRRGTLSSGKTQQYLFNWKAFTGWDYTIGNPETAGNVYMANVIKFREAINDDKQKPSDKHPWIRFVARVLTNLFICAMYVFSIWAIMQCGTLKGEHFFAQNATAITISLITLVFPNIFDLLGKIEKLHPRNALRFQLGRVLVLYILNYYTLIYSLMLQLEHLQKEKNASDNPISALGHPGDAIGRTIRETVLPRYPVDNNPHTYYSYAPVTTTPIPATSSWTTVLPDFGPFGVYNPKASVTKDDTVFSSPVVETHMFGPNSDWNETTVNAASPTGATTRASLRMSQGGLCWETIIGQEITKLVTMDLYMTVASIFLIDFLRGLACRYLNLYWPWDLERTFPEYGEFKVAENVLHLVNNQGMIWLGLFFVPLLPMLNNIKLIILMYIRGWAAMTCNVPASQIFRASRSSNFFFALLILFLFLCTLPVGFVIASKTPSKSCGPFGNQSFFYSVITDVLHENLDKTLVNGIKYSLSPGIIIPVLVLLSLVIYFLIAMVTGLSQANQDLSFQLMVERTEEKKKIFELAGGKKKKSKDNTFGKQKPKQLLPPPTKGVSSDDDSQHNRSTAKSVSGRQFVPSLGSVSEVDHSTGEEQSSDSESTTSSLPPKLSLRQRFLVCIGWADPNKYGRHDDIEMEEGGGRLRELSTGSETDSDDEDSEKSNRDMSYRTAIQSFDQNSQSASASSSKSTTTAPSNSEMRIEITENPLHTYITPLRIEKKSSASSSSSSHQPSSSIEKQAARRLLQPISTTHNIRYGVATVENSSQDPTRPPSTDDSLGDPALHEPLWANLNPHSSYTSAMMSPIMNEVMSNDETTDDEKGRLIPDRPPIPHSPRELKRLKREKDQQSESGSKPSTPRPPRFRISMSPPRKPPSEKNDSDSSNRKYEMRVEKSPKKPKKSDND
The following text describes a protein:
Function:
tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.
Sequence:
MAGPRLPVPRLAGVSQEQFMQQLYPQRKPLVLEGIDLGECTSKWTVDYLSQVGGRKEVKIHVAAVAQMDFIRFFCVYFRTLPFDKLIQRAAEEKHKEFFISEDEKYYLRSLGEDPRKDVADIRKQFPLLEGDIKFPKFFKDEQFFSSVFRLSSAGLQLWTHYDVMDNVLIQVTGKKRVVLFSPRDAQYLYLSGTKSEVLNIDNPDLDKYPLFSKARRYECSLKAGDVLFIPALWFHNVISEEFGVGVNVFWRHLPSECYDKTDTYGNKDPTAASRAAQILDRALKTLAELPEEYRDFYARRMVLHIQDKAYSKNFE
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MSAPQHHFMQGLNNSQQTALRNQFASTMQSQMGTTMQNQLPVHMGNQMNNPMMSQMASTLNNPTMPNSQIMGQLNQQYAMNPANQIAQHQGGNMQMQQGSMEFSNNLQHHAMQANQAQMVQQGGAVAPAPQIQAQQQQQQQSKEFNTASLCRIGQETVQDIVSRTQEVFQTLKTIQPPNGTPQSSNASNEKKAKVQEQLRTIRVLFKRLRLIYEKCNENCQLQGMEYTHIESLIPFKDEHDPKHDEKKNSEAYRLACEECKEVMEQVILKNKQLKDVIDHLRRIIWEINTMLTMRRS
The following text describes a protein:
Function:
Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Sequence:
MAHRLPDCSKLRLFNKGVSVGSSFFTPAPLVGYAALRHPRAISTSNTSKKPAVAIPTGPVSPLVPATHVGTSSASTSEVRDGNAFATLPLTWPHDGWKENVLLNVVPSHREPRTFGDWVAWKIVRTCRFWMDLVTGMRPEQQVDSKNPTTALAASKPLTERQWLVRFIFLESIAGVPGMVAGGLRHLQSIRRFQPDQGWIKSLLEESYNERMHLLTFLEMYKPGWFMRLVVLGAQGVFYNAMFISYLLSPKICHRFVGYLEEEAVHTYTRCLLELDHGCLKRWSDPNFRIPDIAVRYWNMPEGHRTMKDLILYVRADEASHRGVNHTFGNLDQVTDPNPFMECPGGGVVKAFPKHLSVTRPAGLEREEVVSKETH
The following text describes a protein:
Function:
Inhibitor for carbonic anhydrase 2 (CA2) (By similarity). Does not bind iron ions.
Subcellular Localization:
Secreted.
Sequence:
MRLLICALLCLGTLGLCLALPEKTIRWCVVSDHEATKCSSFRDNMKKVLPAGGPAVTCVRKMSHPECIRDISANKVDAVTVDGALVAEADLPHHSLKPIMAEYYGSKDDPKTHYYVVAMAKKGTGFQLNQLRGKKSCHTGLGWSAGWYVPLSTLLPSGSRETAAATFFSSSCVPCADGKMFPSLCQLCAGKGTDKCACSSREPYFGSWGALKCLQDGTADVSFVKHLTVFEAMPTKADRDQYELLCMDNTRRPVEEYEQCYLARVPSHVVVARSVDGKEDSIQELLRVAQEHFGKDKSSPFQLFGSPHGEDLLFTDAAHGLLRVPRKIDISLYLGYEFLSAFRNLKRGLEDSQRVKWCAVGQQERTKCDQWSAVSGGALACATEETPEDCIAATMKGEADAMSLDGGFAYVAGHCGLVPVLAENYLSTHSSGRLGSKCVNAPLEGYYVVAVVKKSDVGITWKSLQGKKSCHTAVGTSEGWNVPMGLIYNQTGSCKFDAFFSRSCAPGSDPDSPLCALCVGGNNPAHMCAANNAEGYHGSSGALRCLVEKGDVAFMKHPTVLQNTDGKNPEPWAKGLKHEDFELLCLDGTRKPVTEAQSCHLARVPNRAVFSRKDKADFVRRILFNQQELFGRNGFEYMMFQMFESSAKDLLFSDDTECLSNLQNKTTYKTYLGPQYLTLMDNFRQCLSSELLDACTFHKY
The following text describes a protein:
Function:
ATP-dependent specificity component of the ClpAP protease. It directs the protease to specific substrates. It has unfoldase activity. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins.
Sequence:
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRSEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDIVNFISHGTRKDEPSQSSDLGNQPTGDEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSVEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDNAIEALTEAIKMSRAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNLLLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMGEIKKVFTPEFRNRLDNIIWFDHLSGEVIHQVVDKFIVELQAQLDQKGVSLEVSQEARDWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNALTYDFQSAQKHKPEAAH
The following text describes a protein:
Function:
Seems to be involved in regulation of potassium-sodium homeostasis. Functions as a high-affinity sodium transporter, which mediates increased sodium uptake in roots under potassium deficiency and contributes to sodium accumulation and salt toxicity. Involved in nutritional sodium uptake and distribution in potassium-starved roots to allow plant growth. Functions as a sodium-potassium cotransporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Localizes to the plasma membrane.
Domain:
HKT transporters are proposed to contain 4 pore-forming regions enclosed by transmembrane segments with each containing a potassium channel-like selectivity filter motif.
Sequence:
MTSIYHDFIHNKLQSFGRIGRYFVNFVVLAHRFIALHIHPFWIQLSYFLLISILGSVLLMFLKPSNPEFRPGYIDMLFLSTSALTLSSLITIEMEVLSSSQIVVITLLMLLGGEVFVSFLGLMLRLNHKHNPEFSGDKVSSVPIELDTINSASTVISCEELQLEAAIPEVPSSTIKDLKRSKRLRWFLGFVVFSYFVVIHVAGFLLVLWYISRVSSAKAPLKKKGINIALFSFSVTVSSFANVGLVPTNENMAIFSKNPGLLLLFIGQILAGNTLYPLFLRLLIWFLGKVTKLRELKLMIKNPEELQYDYLLPKLPTAFLASTVIGLMASLVTLFGAVDWNSSVFDGLSSYQKIINALFMAVNARHSGENSIDCSLIAPAVLVLFIILMYLPPSTTFALSNGDEKTANKKAKRKLGLVVQNLAFSQLACISVFVIVAFITERSRLRNDPLNFSALNMIFEIISAYGNVGLSTGYSCSRLQKLHPGSICQDKPYSLSGWWSDEGKLLLVFVMLYGRLKAFTKGTGEYWRLW
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MPGDLNLKKSWHPGLHKNQAVVHAKEQEALEERRRIQERQKEIKQQRERDELQKLQEMATGKKRVQKVEWMYQDPTAVGSQQAFNEKKVDANSTDDYLLGKRRIDSIVKQKGDLEAFDDSLDRFQPKTDKSESAGIVHKVKDDPMVAVRQKGRELGYTDEANESERRSRRERSRSRERERRRPRRKREDSRDRRNRRDMEREGERRRRRRDGERTRRRERNRDPSPSVSDDDRGYRQSSREERDRKSSREEGGRSRSRDRYRNRSRERYRDRSREERSRDRSRERLRSRRDRDRDRDRDRDRDRDRDNVQSSGRSSGRSSVRSSARSERSLRDRSRSRDPDRDRDYRSRSRERDSGGGQGSDLSDEVGNGRSVLDERSTDMNASDGNSSHGYRADNEFSPSRSPVTRSHRDKRNSYRPEYKDEDDKRFAQRKDKEKEMNALPKGLQQMRAKLLASKKTTTVSGTSQTPTSAPSGSQRTPSAASGSSPTGKAATDAKLSDRLARLKAMQEDAKALEEERDERLASKTKHEEAERLRDALLRQKSAHLGRSEFAREEERKDLK
The following text describes a protein:
Function:
DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. Unwinds the lagging strand from forked DNA structures in a 3'-5' direction. PCNA, the DNA polymerase sliding clamp subunit, stimulates the helicase activity, and may alter substrate specificity. Unwinds branched DNA (Holliday junctions) in an ATP-dependent fashion; ss- and dsDNA stimulate ATPase to the greatest extent, although it preferentially binds DNA with a single-stranded region. Processes a RecA-mediated recombination intermediate between gapped circular and homologous linear dsDNA.
Sequence:
MRVDELRVDERIKSTLKERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAMVHRILTQGGKAVYIVPLKALAEEKFQEFQDWEKIGLRVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIKDVKILVADEIHLIGSRDRGATLEVILAHMLGKAQIIGLSATIGNPEELAEWLNAELIVSDWRPVKLRRGVFYQGFVTWEDGSIDRFSSWEELVYDAIRKKKGALIFVNMRRKAERVALELSKKVKSLLTKPEIRALNELADSLEENPTNEKLAKAIRGGVAFHHAGLGRDERVLVEENFRKGIIKAVVATPTLSAGINTPAFRVIIRDIWRYSDFGMERIPIIEVHQMLGRAGRPKYDEVGEGIIVSTSDDPREVMNHYIFGKPEKLFSQLSNESNLRSQVLALIATFGYSTVEEILKFISNTFYAYQRKDTYSLEEKIRNILYFLLENEFIEISLEDKIRPLSLGIRTAKLYIDPYTAKMFKDKMEEVVKDPNPIGIFHLISLTPDITPFNYSKREFERLEEEYYEFKDRLYFDDPYISGYDPYLERKFFRAFKTALVLLAWINEVPEGEIVEKYSVEPGDIYRIVETAEWLVYSLKEIAKVLGAYEIVDYLETLRVRVKYGIREELIPLMQLPLVGRRRARALYNSGFRSIEDISQARPEELLKIEGIGVKTVEAIFKFLGKNVKISEKPRKSTLDYFLKS
The following text describes a protein:
Function:
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MTSRPALGTHGSGAPSRNQVRRPSKPANALPPDCIDPTLEDERPAAHNGASEARPPPRGRPHIFYSTLASSAFDLPIHSFPYQPTVNLPVPPRPGSLHLRDASQQRQILPGGTGVKDAPKLGVPETVPIPVHFPGEKAADVFPWTGTNAEDTLSEALVKAGVSNKPQIMNETNTARPSLWSNLKNKSGITTLSTLFVAVLEKRQQNGRLQTPNTFKPPPRLTLRDSTREGWLHDLANPTVSLRRLSRTIPHGLTGKVLLDQCLNKNIPLPRALWLAKCVGINELRAHKRKGQAGTVTWGRGWTSSVEQFLDSVISTIGQGDWKLRITYALQLATHLYKEHLLDDDHFLGWIPFGLDMCSSERLFIWLLVVAVPHYWNDISSCRQRGKRLAESLLNHLAKLSPIEDLAAPSTALQFLENSLLKLVTTRPACLLLPISWPKHSAALKALVTKRNLPQTAQAVEKLDGRNTRLLSFVRNGKSSSRTGAARVFHKLDSINYAAPIRIEDLSYECMEITSNAVQLISTLLHWACSCYRAGSHRIYLATRLLRRWSHLGADVYEGIIVYLQSMSWVKSGEIHVLLRIVAELVRSKHFSVGRYLQWLIATGSLGCDASLSLPSSWPVRLITEVPLTGLSDQVRTLRSTLLRGTAHSTELEEQALVNVKQSISQAVPAIFGLSLTIPSRIELNFAKLSGTIRLEIGIWLRQQVAQHAEVNEQSYLEQCEDLAILADVIGITASSLDMAVLASVADTLLYHMKTFRAIGAFDPLLGRLAMRYAAIRTVKFPERELLLSFQNLARTAQPDGQLLQLLAYDLSRLDQKNAVAACSPASDNMGEVMQHAGTCSDDEIERILSSGTSMDQNMMSRVLRKLVRNLEEHVDKGYRQFENHPAWFWRLRNFDEATFDVVLREWLETSIMACQLHILQIAIPPLVASSCMELSSFLDILRSCLANAKATQVLEPATIAIDLLRLLLPSGLSAMSCSSQDAYRYRTEQYKLCFTSDTRIIHCIGEVADLVLSTPSNSMLQTVSSLLSSETVLSIVKEHVVSDPDCLSKMKTGQSGQASFNTCFKTLLNGLLDPSGQWCLADISPEEQIIAVFKAASELSLPLCQAMIEHIFASSSALDTHAVDRLSVTVLNAVRTSMEKDQSQGLELLTNLEGPLADKIRSHAEREVLDASYFLLRGSTDGIASDCIVTAKMMQKYLTVIELTMGETPQADEQFAMLAALTDRFKGIFHALSECGGLGTPTNQATASPVVQVLAALLSLVASHGPQLLRNATQSHQAALMVALQDIVTHASLELFPSIIEHVFDVLIVLSDHISEDVRNQIARLESAKSTNSDRAYFIHSQKAPIDGWLMLTKPVIPPLEPPQPPNPNTTQNQSSPYQSPQMTSNTAAPQHRYFNQQQQQSQTLQPSQQTQHMRTYPQYAQHAAQPNRHLPAQLQRTPSHHASLSPLQQMQHMQQLQGLAQQRASQPSPIHSQRPTSVASPGGMGGLAGGNAAPSKAHTSYVNQQRDTQQYPFVQPRWEILAESSGNPTLNETAISLSLFGARRV
The following text describes a protein:
Function:
Nucleic acid-binding protein that promotes Pol IV-dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA-directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II.
Subcellular Localization:
Nucleus. Nucleus, Cajal body.
Sequence:
MTEYWVSQGNKWCEFCKIWIQNNPTSIRNHDLGKRHRECVDKKLTDMRERSAAKDKELKKNEKLLQQIEAKATRSYQKDIATAQQVAKANGAPEDGTSDWMLDSASGYYYNQTNGLHYDSQSGFYYSDSIGHWVTQDEAYAAVKTSSGTKVPLVKKPVSSSGAGPSVGKPPGRLVTASLNPKRAVKGAASSVDLGNNKRKRQDEKPKKVSAEEKAALKAREAARKRVEDREKPLLGLYNRPF
The following text describes a protein:
Function:
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Subcellular Localization:
Nucleus.
Sequence:
MAGEEDLATAEAEGDKDELEDEEEKEVCEDQFHPGSQSQAMAPAIISIHPNSRAIVVSVGAGFRVFDLESNEAVTPVDDSSGHRAAIRASGFSHDGAFFASAGDDKLVKLWDTFSWKCSKTIPVNKKTSAVAFSRDGQWLLVADKFGVVYVIPTLAHDKSDTNEEPAQLLAHCCSIITSLETSPCGKFVVTADRDYKIRVSVLPKNPMLGAYEIQSFCLDHTSFVSCLAFVGDGSSEALLVSGGGDSTIRLWDHVSGHLLDTINIFNLLQTDKTDTFVAPAVVNTSASGSVVASTIERCLFLKISWQEPICPTGLQFDRKERLWLVAGAAETREVGDRALKPEQVTELTSLAQASAAGALTRLRVIQKSPATSSYEALDDTEVPGGDRMLKVLQGSPSDSSVSVAAAVAEAAQAAELAMKNLLSKRQYTETHREKRKRTRNDKKARAATSS
The following text describes a protein:
Function:
Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
Subcellular Localization:
Membrane.
Sequence:
MTTNTENQTNSLDIVKWGLAILLLAAAVIGNQMYSEASAVIRALAVIVAFAIAGFIVLQTEKGKKALAFARESQIEVRKVVWPTRQEALNTTFIVLAATGILALILWGMDAVLMRIVNFITGV
The following text describes a protein:
Function:
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU). DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. Probably also acts as a DNA helicase. Recognizes and binds specific regions of the genome, hydrolyzes ATP and allows the DNA base J de novo synthesis. Involved in initial synthesis of DNA base J, JBP1 being able to act via the basal level of DNA base J and propagate further synthesis. In contrast to JBP1, it does not specifically bind DNA base J, however it binds chromatin (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MLNGLTRVSTSSELESILDIVQSSGEIAVVFTSPSIGDLETIASETQRRQLRIAGIPRGGYTILPAIPLYDDELLQMCERYTAANEYEKAEMRNSLYMREYPLFAYSMRHQRALFHPADYVSRILQFCSYYVQAPDADVLSLQDRSPFLHISPIKEICTQLRLIARGTPVAASDSESPVPEQLRLHAESDVEKLAAERATAMSIAASSGGASETEQLSLFSGVAPSALFQKDAVEEVNKDAEDTMEDLTGEETVDAVHSFQAEYLTLDGFELVTKASIFYDREGEGQCIVAVYIPGGVPEDTCRAAAAVLEPAATKKNLRAPTNGGLPPDTGIVGYYDYLTNPTQHKCRETEFSRRNWGLLAQSEPLLKHLDKLYSQLAPMHHHLQRVAIPSQYQLCGTVFSTITVNRNFRTAVHTDRGDFRSGLGVLSVINGEFEGCHLAIKRLKKAFQLKVGDVLLFDTSLEHGNTEVVNPEIHWQRTSVVCYLRTGLMSSVCEMERRKHLNRLILEQLLNTEVRNTTVNINGADSSLPPLFVPTRLASHLAPVQLAALGFIVERTEKQSGCVVAMTMGLGKTLVALTLCFSQLYLAPQADILILTPKPIISHWVDEKNKWGMHGLHFPHFVASDGLNSLEFEQQLLEYERQKNNEKPKSGHIFVINGEYLAGFLRRFKRFTPLVMIVDEGHRVAAKGNKLTESLDRLRCNLRIVLSGTPLQNDASELYRLVGWVNKGVSRVLPPKRFQELANDINQFVEGDDGAFYNAVVAQEYIQDWMRGFVFREMENDLPPLHDYLLICGSSDVQREYEEKLGLTETAMTALKATEHRPHHLSTHPACYLAFISDSYQSMVSGWTVRALSNTSRQRVSQLEEIDTMRLEQYVQLVENEQLDAFIDLSGKMRVLVDIVLRVQARKEKLIVFSLYVGSQDLIHRTLTALRVCTFTVRGRDSQDRRRRAMQEFSENKDLIVLVLSTKIAAYGLDFTAANHVVLFDSWWNPQVDAQAIARAYRRNQRKPVTVYRLISATENKFVLRSQTRKIALFKCILHERTSRQALPDELEDCAANEKDEERRNFWAKLKMTSLAGDTRALLNVYRYQESVRESE