lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Putative single-stranded-DNA-specific exonuclease.
Sequence:
MEYRLIGDNDYNFDPLATILKNRGIEDPKLFVNVDQSSVIHYSKLNNIDKAADCLIRHLNNKNKLFVQVDSDVDGYTSSSIIINYIKKICPKANIHYRIQDGKEHGIFIDTIPDDVDLVIIPDAGSSQFEEHEALNKRGTEIIVIDHHECERVSEHAIVVNNQLSPNYSNKTLTGAGMAYKFCQAIDEKLNKNEAEQFLDLVSIGNIADSADSRNLETRYFMNEGLKKIKHPLLKKLFKKQEFSTKGDKSIQNTQFFINPLINAAIRVGSSEEKDQMMRAFLLSKEKVPYKKRGQSETELVSIHEDTVRILGNLKAKQKRIVDAAGVEIKNRIEEKSLTANKVLIVYIEGILDKSLTGLVANQLAEEYKKPVLLARNDPEKGKDILSGSIRGYDKGFIKDFKKELIDTGLFEFVEGHPNAAGFAIKRQNLILVNKVLNEKFKDINIEEDIQNVDFEIPAKRLRKEFILQLDGYKDYWGYKVEEPLIAITDLEIEVEQIEHLGKKNKTTVKFKHGDIEYIRFKSDENYFNQLTASNGTLVINVIGKAKANEYKGKKTPQIEIYELEVVRTKQKELVF
The following text describes a protein:
Function:
Involved in signal transduction through the Wnt pathway.
Subcellular Localization:
Nucleus.
Sequence:
MSTEQEKESFSLKRNRGGEAGLDVLAGPGLLLGSPDKKRRKSSTQAPPFSPLSEYAPPPNPSADHLIAANPFDDNYISPSLKPYFGHSHYPASNSYGSSRMPSPYGPTIQTQPQYFSQNPTGFSRTHRFNYSPNYVHAFCGGSNNNNNMHFGSVEHGDQIPLQNLNQRSPGFNPDANTTRNMSPNLNNFTQSNTKQDHSEAANKKYSHNVNCEENATQDNKTKGGPEKLNGVFHSNNEKKSPDYRRSALRMNKVKRRSTSSSSEPVFPCGICLNEVNDDQEAILCEASCQKWFHRVCTGMTETAYNLLTAETSAVWGCDTCMEDREVQMMKNSDGQS
The following text describes a protein:
Function:
Involved in the synthesis of tocopherol (vitamin E). Catalyzes the condensation of homogentisate and phytyl diphosphate to form dimethylphytylhydrquinone.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MATIQAFWRFSRPHTIIGTTLSVWAVYLLTILGDGNSVNSPASLDLVFGAWLACLLGNVYIVGLNQLWDVDIDRINKPNLPLANGDFSIAQGRWIVGLCGVASLAIAWGLGLWLGLTVGISLIIGTAYSVPPVRLKRFSLLAALCILTVRGIVVNLGLFLFFRIGLGYPPTLITPIWVLTLFILVFTVAIAIFKDVPDMEGDRQFKIQTLTLQIGKQNVFRGTLILLTGCYLAMAIWGLWAAMPLNTAFLIVSHLCLLALLWWRSRDVHLESKTEIASFYQFIWKLFFLEYLLYPLALWLPNFSNTIF
The following text describes a protein:
Function:
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Subcellular Localization:
Nucleus.
Sequence:
MSEASSITRHPYKANTGPLLKFQQSSDASSLPPMARPMASRQLATSHTAASNVSVAGDDGIDAELWYACAGPQKALPPVGSVVAYLPQGHIEQVASFNNQELDAQIPRYNLPAVIPCMLNDIQLSADPDSDEVYATLTLCPMSEQHEDSSDCAEPPPPPKRKSRSFTKTLTVSDTSTHGGFSVPRRAADDCLPKLDMSLNPPNQELVAKDLHGNEWRFRHIFRGQPKRHLLTTGWSVFVSQKRLVAGDAVLFLRGENGQLRVGVRRAPRQQQLQPKVLTSPTMHIGVLAAAAHAATEKSRFSLIYNPRSCPSEFVIPYSKYLKAVKSNFNVGQRFKMKFESEDPSDRRHTGTITGICDFDPARWPGSEWRSLQVNWDESSSSERQERVSPWEVEPFSPSTTITPSVSTRKRLRPVTQPHSESVNRNAVETSKAQTQTMRLARAFHGGHEMLPSSAEEEDAESLSAKMSWIKREDNFKSEAQSVGSRQGPDSWMSIRRPDPVQVPDMFRNLPASGVPDLRGMIGIERRQQEHLKFCVKQYRENKDEISGTTLQLSSPRPPNLQNYVKSSTDLNLSVSSPASSNKGSSLLWSNSQSVTLPSYNGHESTNASSWLSFRPGQSDVAASSPHCTTLSMSNLPPADSETSSHPSTPKSYLWEKRIRMEPDTNRAAAPVQSEQKCKIFGVPLDKPTPIVIPSQVPGSKAVRSTDDGSGPSSSRGLEKVVSPSPTSSAVGGQEQDKGPQRSNKTSQNFQQGPVRSYTKIHKQGSFGRSIDVQSYDGYTDLLRKVENMFELNGELFDKKSGWQLVYTDHEDDVLLVGDDPWMEFVSCVRTLRLLSPGEASSSGKSGQSHDEDAGAGKDGAKRCDSSSPSAGARGDDM
The following text describes a protein:
Function:
Probable cell surface protease.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MKPENGAATWHPAKRSCLGRLTTLETLLLVFLGLLITALLSVLFLWLWVLDGYKTFTDGRPIYPLPFENSSVAVDRSAKNHNDVVCTSRECVRLAGFLAENLNSKINPCEDFYEFACGNYGLNKNLPANKPLRHTISDVQSRLNKQVKSMLQSPISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRIGGWPTLEGDKWQEWSHSWEEQIALVLNLTGVNAVILEMAVTHDPSNSSRSVIELDQPKWGAGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAIAEKEMNEAMEFELKLVNFSADDMVRRDPERGNNRFELWQLKSVFPFINFEKYLKTVFKELVALSPNHTVIVREIDYFVGIQHVLQSTPKRVLANYISWRLVQGFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFVENFFEKERAMKKMTELTSYLKNEFIKQLHVLDWMDEITRRRAISKANMIEYKSGFPMVLFNDTWMEKNWGMIIKPREYLLHLTIRVKLVRFTEELLRLDQPLDRSMWFQSPAQVDAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEKTRCFVRQYENVHVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAWKSNTTGISEPALPGFQNFTSQQMFFLAYANNWCSLVRPKHYIQIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPIGSPMNPERKCQVW
The following text describes a protein:
Function:
A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
Subcellular Localization:
Cytoplasm. Note=Binds to ribosomes.
Sequence:
MATRHDIRNVAIVAHVDHGKTTIVDGMLKQAGAFAAHQLEGVDDRMMDSNDLEREKGITILAKNTAVKYHPKDGGDVITINIIDTPGHADFGGEVERGLSMVDGVVLLVDASEGPLPQTRFVLRKALSQRLPIILCINKTDRPDARIDEVVNETYDLFLDLDADEEQIEFPIVYACGRDGVASLTKPEDGTVPSDSTSLEPFFSTILDHIPAPTYDEDAPLQAHVTNLDADNFLGRIALLRVHQGELKKGQTVAWMKRDGSVQNVRISELMMTEALTRKPAEKAGPGDICAVAGIPDIMIGETLADVENPVPLPLITVDEPAISMTIGTNTSPLVGRGATGKGADNKAVVKDRKVTARQVKDRLDRELIGNVSLRVLDTERPDAWEVQGRGELALAILVEQMRREGFELTIGKPQVVTKEVEGKTYEPVERMTIDVPEEHMGAVTQLMGVRKGRMDNMSNHGSGWVRMEFVVPSRGLIGFRTEFLTQTRGTGIAHSIHEGHEPWFGTLTTRNNGSLVADRSGAVTAFAMTNLQERGVLFTDPGTEVYEGMIVGENSRADDMDVNITKEKKLTNMRSSSADSFEAIVPPRKLSLEQSLEFCRDDECVEVTPEAVRIRKVNLDARERARAASRAKHG
The following text describes a protein:
Function:
This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).
Sequence:
MKAKDIAELLDEPACSHNKKEKSGCAKPKPGATDGRCSFDGAQIALLPVADVAHIVHGPIACAGSSWDNRGTRSSGPDLYRIGMTTDLTENDVIMGRAEKRLFHAIRQAVESYLPPAVFVYNTCVPALIGDDVDAVCKAAAERFGTPVIPVDSAGFYGTKNLGNRIAGEAMLKYVIGTREPDPLPVGSERPGIRVHDVNLIGEYNIAGEFWHVLPLLDELGLRVLCTLAGDARYREVQTMHRAEVNMMVCSKAMLNVARKLQETYGTPWFEGSFYGITDTSQALRDFARLLDDPDLTARTEALIAREEAKVRAALEPWRARLEGKRVLLYTGGVKSWSVVSPLQDLGMKVVATGTKKSTEEDKARIRELMGDDVKMLDEGNARVLLKTVDEYQADILIAGGRNMYTALKGRVPFLDINQEREFGYGGYDRMLELVRHVCITLECPVWEAVRRPAPWDIPASQDARPSGGPFGER
The following text describes a protein:
Function:
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Is also required for urease maturation.
Sequence:
MHEYSVVSSLIALCEEHAKKNQAHKIERVVVGIGERSAMDKSLFVSAFETFREESLVCKDAILDIVDEKVELECKDCSHVFKPNALDYGVCEKCHSKNVIITQGNEMRLLSLEMLAE
The following text describes a protein:
Function:
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.
Sequence:
MEFKFAVNDVFKQPIVKIGNNLLPPGFTGDRRAFWDVVGKVSEVVNAMGEASAAAQGLTKPITTAERLRNSEHSVYLLIDQNAGNGRGAVTGMLKTGMKGLYVFDRNGQHYQVSPPCVLDFYVHESRQRTGLGKRLFEHMLQTESIEPVKMAIDRPSEKFLGFLNKHYSLNNPVKQMNNYVVFDGFFPGAQDKNGTVESHSSHSNTPVGKKQSANGLQTSTYASPLGRYGAPRPPCSMGQIIHNQTSTIAKTPEPTGVRSAPETNYQSVTTNSPNISQSTPNMYYQKYDGLAPNAEQMQYYQQQQQTSQPIIQATSQPVIQSVPQETTKVSSVPHMSQPTLLPPQYSQSQLAQNQNMEQTQPNVQNVHQIRPQANIYTLPSSEYQMQYTGQQNNDTSQPPQQNVSKTQMKPIENEAQNQQVDNLNGNETTDQSAMVNGGKGDMANPVSDESGLRYGYPPQVNEPMRQASMKMISVKGR
The following text describes a protein:
Function:
Pore-forming subunit of the CatSper complex, a sperm-specific voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.
Subcellular Localization:
Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.
Sequence:
MSQHRHQRHSRVISSSPVDTTSVGFCPTFKKFKRNDDECRAFVKRVIMSRFFKIIMISTVTSNAFFMALWTSYDIRYRLFRLLEFSEIFFVSICTSELSMKVYVDPINYWKNGYNLLDVIIIIVMFLPYALRQLMGKQFTYLYIADGMQSLRILKLIGYSQGIRTLITAVGQTVYTVASVLLLLFLLMYIFAILGFCLFGSPDNGDHDNWGNLAAAFFTLFSLATVDGWTDLQKQLDNREFALSRAFTIIFILLASFIFLNMFVGVMIMHTEDSIRKFERELMLEQQEMLMGEKQVILQRQQEEISRLMHIQKNADCTSFSELVENFKKTLSHTDPMVLDDFGTSLPFIDIYFSTLDYQDTTVHKLQELYYEIVHVLSLMLEDLPQEKPQSLEKVDEK
The following text describes a protein:
Function:
Controls the reversible conversion of biologically active glucocorticoids such as 11-dehydrocorticosterone to corticosterone using NADP(H). Participates in the corticosteroid receptor-mediated anti-inflammatory response, as well as metabolic and homeostatic processes (By similarity). Bidirectional in vitro, predominantly functions as a reductase in vivo, thereby increasing the concentration of active glucocorticoids. It has broad substrate specificity, besides glucocorticoids, it accepts other steroid and sterol substrates. Interconverts 7-oxo- and 7-hydroxy-neurosteroids such as 7-oxopregnenolone and 7beta-hydroxypregnenolone, 7-oxodehydroepiandrosterone (3beta-hydroxy-5-androstene-7,17-dione) and 7beta-hydroxydehydroepiandrosterone (3beta,7beta-dihydroxyandrost-5-en-17-one), among others (By similarity). Catalyzes the stereo-specific conversion of the major dietary oxysterol, 7-ketocholesterol (7-oxocholesterol), into the more polar 7-beta-hydroxycholesterol metabolite. 7-oxocholesterol is one of the most important oxysterols, it participates in several events such as induction of apoptosis, accumulation in atherosclerotic lesions, lipid peroxidation, and induction of foam cell formation (By similarity). Mediates the 7-oxo reduction of 7-oxolithocholate mainly to chenodeoxycholate, and to a lesser extent to ursodeoxycholate, both in its free form and when conjugated to glycine or taurine, providing a link between glucocorticoid activation and bile acid metabolism (By similarity). Catalyzes the synthesis of 7-beta-25-dihydroxycholesterol from 7-oxo-25-hydroxycholesterol in vitro, which acts as a ligand for the G-protein-coupled receptor (GPCR) Epstein-Barr virus-induced gene 2 (EBI2) and may thereby regulate immune cell migration (By similarity).
Miscellaneous:
MISCELLANEOUS: [Isoform 11-HSD1B]: Kidney-specific.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MKKYLLPVLVLCLGYYYSTNEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDMAFAERFVVEAGKLLGGLDMLILNHITQTTMSLFHDDIHSVRRSMEVNFLSYVVLSTAALPMLKQSNGSIAIISSMAGKMTQPLIASYSASKFALDGFFSTIRKEHLMTKVNVSITLCVLGFIDTETALKETSGIILSQAAPKEECALEIIKGTVLRKDEVYYDKSSWTPLLLGNPGRRIMEFLSLRSYNRDLFVSN
The following text describes a protein:
Function:
Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC3. Participates in the incorporation of the c-ring into vestigial complexes. Additionally influences the incorporation of subunits MT-ATP6, MT-ATP8, ATP5MJ, and ATP5MK in the ATP synthase.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MSEAGTSADAVAAEKERKFRIQAAAFLGLVGGVSALFGFSRTLATAKKTDSKVLQQAGTRQGMILMDEGATLALRALGWGTLYAVMGTGAFCYGFWKLSGAKDFQEFRLKMGNALPRITKDEPPASRTDFESLTDLMKYLAAWNKE
The following text describes a protein:
Function:
Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Also modulates progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR (By similarity). Required for normal spermiogenesis. It probably plays a role in acrosome formation.
Subcellular Localization:
Cytoplasm. Nucleus. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mainly nuclear.
Domain:
Contains 2 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs. The first one is essential for the association with ESR1 and ESR2 (By similarity).
Sequence:
MRSSEGAPSWAVALPPPLRPCAYGVSEVTRCWHQLSLGAGESSMNPSATLYRRQNIGSEVETSTIEKQRKELQLLIGELKDRDKELNDMVAVHQRQLLSWEEDRQKVLTLEERCSKLEGELHKRTDIIKSLMKKVKTLESNQAECQTALQKTQQQLQEMAQKATHSTLLSEDLEARNENLSSTLVDLSAQVGQLQAREQALTTMIKLKDKDIIEAVNHISDCSGKFKLLEHALRDAKMAETCVVREKQDYKQKLKALRIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELIFTVEREKRKDELLDIAKSKQDRTNSELQNLRQIYVKQQSDLQFLNFNIESSQELIQIHGLKMEEPKALECSKDMCLSDLDNNYPKIDIKRERNQKSLVKDQTFEVMLAQHNGSDKSSCDACREKKLQVNTALGEKSVIALSSLFTKDLLDKQKSWSLGGKIQTEPENKVTLCKVHAKSPKCDGVGLPTEEKQLSETSVSLSDEKQWHDINVYLGLSSCSKQPDRLDGDGHDRTGTSEVSCCTPNVVCIGDNDLSESKCCHPSNIIIEAPGHMTDTEWMNIFKPSRAQRIVRHKTMCTCSRSVSAMKYNSSASELIGMQPSQCVGSLKSAEREEESAALPDRRTSANEKDDFSPTSKLQRLLAESRQMVTDLELSTLLPISCENLNRSKLEVSEEPDEKTTLVSH
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MLRNFVPMATRVSTRPLAGQPTKSYTDGLGNMEQTLKEASLRKSAAESKKQSGSAAHQADSVREENDYHSSMLGSEYIVGGENEMVGGYPDMQTRPLPRVAHIYQQNEWNQTTWKIDYADDDFMESKLTGPSFGDLLPNVSMHMRFASKNDAIEFCKENNWKYQVLPKY
The following text describes a protein:
Function:
Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSNLKVACFTLVVLFGSSSWMGTNSVWMQLPLLTSSLPEGWSLPSYLAMVVQIACIGPLVYGLLHKCCCSLSSAALILAALLMAVSCQSGLAVFWSYTAGGYSVLLYAFMFGLALVNATSNVLFMPFMSQYHPSLLHAYFVGMGLSSLVPSLLSLGQGTSNFECVANNGTMQPVFQPPRFSVSVYLWLIAAWTALATAAFVVLQYREWSDEQQGEKHECDSCTEEATPLKDGRGNEVRTTSVEDPSSHCPSSSPPSYHASPFMLLLLTAVVNAQMNGVIPSVHSFAALPYSQSVYHLGLTLSNIVSPIASFLPMFVGVRSLAILSGLTALSTVTTAFIVYLGLLSPGYLAESQTAGGVFSVLSVVVAAGLHSFLRTTFASSLRESGGGRSEHWLFWCGVFIQIGSFLGSAVMFPLINYTSLFQSAPMCQ
The following text describes a protein:
Function:
Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length (By similarity).
Subcellular Localization:
Cytoplasm.
Sequence:
MTKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVHISDVGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRTINRSLVLAIADGTVSVDGREIYSAEGLRVGLFTSTDSF
The following text describes a protein:
Function:
Plays a role in stimulating adipocyte differentiation and development.
Subcellular Localization:
Membrane; Single-pass membrane protein. Nucleus.
Sequence:
MKYPLVPLVNELTFSFLASWLCLPVGLLLFLLIVWLRFLLSQDSEENDSDLCFDWEPWSKGPAEFCQEETLHSPEEERPCW
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. Involved in the export of mRNA from the nucleus to the cytoplasm. May play a role in mitotic spindle formation and/or function.
Subcellular Localization:
Nucleus. Note=Nuclear rim.
Sequence:
MQVDPVVYQLQRAVSQDPIAVKDAEGHLNNWKKEPGFFGKLYSIFLDKQNDMSLRWIAIIQLRNSIDIIWRKNTKMSLLPEERDFIRCNALLGSIKSENLLSIQNALVVSRIARLDYPTEWPSLFHDLLGKLQQSLGTGDYDVALRLLITLHHIIKAMAGNRLLRSRQIFYKLAPELLTILQPILHSSLSSWMMILESSKEIKDSTLLSYMQISRYTLKACRRLVVFGFQNPSESEFSERMLAFCAVHQRKLLSMLGTMLQSSRSPIVVGECLEMAFAHAFLFNKPFFDFSFYSPCLTKFPATIDYISLHYDFLGQISSHLSSYKEKFEESSKNFEKLVIMSLRVFILVIQEFCNTKSSHPETAQVLYNSFLVDNRINNLLDLLITKLLILKEEDFEEWTDSPQQWVLEQSTQDVEFNVRPCAEKLLKCFFDAYGDIIVSPFKDMIYSVFECPKTLTQAVQQDTLISSFGVGYTQLKSIFPFAKWLQEAAVPNMASINDIGISRVYRRRIAIFLSQWIEDSSSEQLLEVIYKLYCSFLNLTDPCNDAVVILTTIDAFKTVLDDWNFSENSFLSIKENLFVHVLSLFKAFESVDARTSILSLLGTLLARAGEHVAPMESTIASLLSQLWDGWKKEPLLRARVLAVMHQFVNAIKAKSFEFSTFLYTVIEYCVNPESPEHVIFEADAMELWSTFLMYIQKLPETFTLLIPHLLYHLSQATSTLPFVLMIVSSYQLLDNTVLMKDYSFTIFEKLNDLLDDVKNETLQALCKTVCLLIETTPMDMIYESLLNSSLLSRLLLSIATNDKHPQVLIEYLLVVSRISLREPELILKVCQTKNINIAMLIGNWILLNDHINHSKDRKLNTLALSSLLRTNHPDVLAVLDSIMNLWFSVLSEVEEDANGDATIYYKNDDYSAVGFYLDETSEEMTRRKQLLLKDPVHSVNSRSFFISVFMFCRDANGGMENFQNQYLSTVNPALLEQFQSML
The following text describes a protein:
Function:
Deubiquitinase with endodeubiquitinase activity that preferentially cleaves 'Lys-48'-linked polyubiquitin chains. Shows only weak activity against 'Lys-63' and 'Lys-11'-linked chains. Has a role in meiosis.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKCLQQLKRQLQHFGIDGCSLADGDIDYFFTVTGIDRGWGCGWRNIQMLISWLQYTNPNWFKRNFSSGNYEINSLQSLLLSAWMKGIDAEGYAQLGDNLHGKWIGATEVYSLFTGLFVNVALVDFDFRSEASASNALFLYVKKHFESSNDTSNVSPCYLQFQGHSIIIIGFCSSLETLVVLDPDRYQSVQKKFVNIADFNHCYMRKKRSLKFSQFQLVHFKQNIFLNDFSSKLEVRSTRISDF
The following text describes a protein:
Function:
Catalyzes the exchange of ADP and ATP across the membrane.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHEDAGVHRGRKFLTDLCIGGTAAVISKTVMAPMERVKLLLQVQNTHAGIASSQRYSGIRDALIRVPNEQGIASFWRGNATNVMRYFPTQALNFAFNDLFRSRLTSEGEKKGSLSYLGRSMAAGGLAGSVTMCFVYPLDVLRTRISVDVGRSRQSREYKLYFLYRSIYFGLYDTARGVYETDNGSEKRKLNFLSSFLLAEGVTAGASYLVYPWDTVRRRMMIMGALSHFTAIETVKAIVRTEGVVGLYKGALANLLRATGSALVMSLYHELQQFVK
The following text describes a protein:
Function:
May be involved in protein secretion and Golgi organization.
Subcellular Localization:
Cytoplasm. Golgi apparatus.
Sequence:
MINTAKYFALLESLRFSKALANTANNSGTAEALEINLRILEKYAKLEIGQQLHELCLEYQLTDDHESSIDPDSDRTICYIIRLQHVLHSIMRNINFHSDAKEDLISVAHLKLCIQASQELSYYSLRCQLHEDFYKSPIFCEAQGKIKANFSLMLLSIQFFINLLHIRQYHIANSMELVQRDLLAAIVSLRVQQDSPLLDKAIAYLWQYESKADFFRNILLFKATTLCPTLAQLLHRQLLGKLHLPQGFASLVEALHQNPNVNSSRNAEIVASIVARKGFSQLAQEKMVLQVLEYCKFYLQNADKMCAGVLSLRRLYDLSDTNQKLIKEILFKHWETLCNPEDIINGLILMDHQELCNRILLWQHLFCSSTVACLPSNLLVPYLPLLLQLYDGLPMELPASSQISAIILRCLDNREMKNELPAILQKLFKWEIEKEPPWKCLNPRIIILPSMNTTQIQVKVAHKDHLADHDMGRILPGLLTSSSHHSLTCKVFLSLLGFIAKQINDKSSASVDFISSEAELKDFLHSKYQLKLDLLIALNQMVAHQPLRAQLSQHTKELLHILKDLLVHRSREQDTTDQILLLVLNLLQEILEGSENIQLSEACKELKEQLHLLGTRSSNPLIQQSVKSLLTIIHGAWRPSEAVKIQPFQRARSLIEEKQSHMQVYGIQMMIDLLKKRDPATLAQGQLIIALALTTLKDKESYTFLNCVRLFVSLVHVMESDVLDKLSDEYLSETAHLDYRLVVGEAILKVAQELGPLCFRYKAVLLNCFMYGSRSPVHEFRMSAFANLAQLCRLLAFQVQNFFHELLQLVNSELTTGGYVPSKRAAVLVLAELLNGMENLLDYQEMLLPIYRLLKAIEADESCDPQMRQHAANGLKILNKKCTKLIQSALEEKSLQKQIKVLGIKDDDSPQRRNRHILELN
The following text describes a protein:
Function:
Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.
Sequence:
MATTTKRAWKLQEFSAHGANVNCLALGSKSGRVLVTGGDDKKVNLWAIGKPSCIMSLSGHTTAIEAVRFSPTEELVCAGSAAGAVKVWDLEAARMVRTLTGHRAGIKALDFHPYGDFLATGSTDTNMKLWDIRRKGCIFTYKGHSSTVNSLRFSPDGQWVASAGDDGYVKIWDLRAGRLLSELREHTAAVTEVVFHPHEFLLASGAADRRVLFWDLENFTLVSNSDPETSGIRSIYFHPEGKCLFSAAQDGLRVYGWEPCRILDCIPLPWGRIQDMAVTSGQLIGVSYNLSNVSIYVIDLKKVAPFVGIGGGGGGGTAFQHGVSFRKSFNKERPPGGLRQSQIKMNHDTIESDEKSSTETEDDGIAADIKDLNHYHNIFQPRGRELSRTPPPLEINSDKESSTVLIGDKVKLDPAIPQVIRPPPPDLVQQHSPLPTPASGNSPVHRPSPSPSPPFVKTPQSGPGRPAAGLSTMRERRNSTSSVTLSSNKTITSITSVERESYNLHTPTNLIAMTSARPDVTHLSGGPPVLPPTGPHTSRGRNPLRRDLVHRKDSIKEVLQPSLSDPENPPKLNNIRHSPSEPSLNMRSHSTSRSSSLTRNRPDLTVPTPKARVNSLYSPFMSSQPPMSTHNVHQDFVPIMSDKPSGLDLEDFMPRKFNSVSMGGGSPSVSGMSSPYEESSSLALEQTEMEIVTNIVQGHQPMMTVLSSRHRNLQIIYNLWQNKDAKVAVETAVTMNDPAVVVDLLSVIIFRPFLWSLDLCVLLLPAIADLLQSKFEVYVNTACNSLRLVLKNFATVIKSNIETPTQSVGVDISRQERFNKCMSCYSQLVPIKAFVLKRQAMAGKMGQTFRELHILLQVFD
The following text describes a protein:
Function:
Vacuolar v-SNARE required for docking. Only involved in homotypic vacuole fusion. Required for Ca(2+) efflux from the vacuolar lumen, a required signal for subsequent membrane fusion events, by inhibiting vacuolar Ca(2+)-ATPase PMC1 and promoting Ca(2+) release when forming trans-SNARE assemblies during the docking step.
Miscellaneous:
MISCELLANEOUS: Present with 1885 molecules/cell in log phase SD medium.
Subcellular Localization:
Vacuole membrane; Single-pass type IV membrane protein.
Sequence:
MKRFNVSYVEVIKNGETISSCFQPFQKNENYGTITSANEQITPVIFHNLIMDMVLPKVVPIKGNKVTKMSMNLIDGFDCFYSTDDHDPKTVYVCFTLVDMPKILPIRILSGLQEYESNATNELLSSHVGQILDSFHEELVEYRNQTLNSSGNGQSSNGNGQNTISDIGDATEDQIKDVIQIMNDNIDKFLERQERVSLLVDKTSQLNSSSNKFRRKAVNIKEIMWWQKVKNITLLTFTIILFVSAAFMFFYLW
The following text describes a protein:
Function:
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Subcellular Localization:
Cytoplasm.
Sequence:
MLHAWRFVPLARSTSALGSGLLRPSRVLRQKRLAYSPFRPPPTWNALQKVEVGHRQTDTGEPTLDGTLDLVGYQLSRDGLLPQTNILGRTLPVPDTSGISAATRRKLERERDVAVAHMKRHGVRLRRSIKETAVTIGCDEAGRGPLAGPVVGAAVSRIPVSSFNNEFDQLYEAPEQFQIFDSKSVSERQRDLVFAMITGHVDFFDIASCKKFVVHHCAGDEATSLTLSSKKLDSHVKLSKLPFKKLLSMQTPYLITYHGYNSAGNYVYFWSIGIANHTYIDEYNIYNASMNTMHRSAQSIWHMLSDARFSHEAAPRPRSSSIAQYLFSRFCTAANHDNEKRYQVPHHLELLKGATEYFDFEPIQPPLVLIDGHAVPGPSYDYFTSVRIGGDVQPIIEGDKRSLSIAAASCLAKVTRDELMNYIDALYPGYGFRDNKGYPVEQHMKYVAKNGLCPIHRKTYRPCRTVLEKGLQRK
The following text describes a protein:
Function:
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MVSRELRTRKGKNTKMAATFGILRLANRNMLLSPQLMTRPFVASGLVHRNRLQPAPTTQFHTSPRSLAAMASSHWNAERVLVLGMLGIFPLAYFVHNPAMDYCLATAVVLHGHWGFEQIVTDYIHGPLLPRLSKMALYGASILAFAGLCYFNYNDVGITKALSMIWHDL
The following text describes a protein:
Function:
Probably facilitates nickel incorporation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEDKEGRFRVECIENVHYVTDMFCKYPLKLIAPKTKLDFSILYIMSYGGGLVSGDRVALDIIVGKNATLCIQSQGNTKLYKQIPGKPATQQKLDVEVGTNALCLLLQDPVQPFGDSNYIQTQNFVLEDETSSLALLDWTLHGRSHINEQWSMRSYVSKNCIQMKIPASNQRKTLLRDVLKIFDEPNLHIGLKAERMHHFECIGNLYLIGPKFLKTKEAVLNQYRNKEKRISKTTDSSQMKKIIWTACEIRSVTIIKFAAYNTETARNFLLKLFSDYASFLDHETLRAFWY
The following text describes a protein:
Function:
Transcriptional repressor. May repress NR5A1, PPARG, NR1H3, NR4A2, ESR1 and NR3C1 transcriptional activity.
Subcellular Localization:
Nucleus.
Sequence:
MGDSARGEPEEEEGEDEEEEEDEEEEEATSVAVGAVGDEEAAPGGGRKGRGGRKARGRPRLTESDRVRRRLESRKKYDVRRVYLGESHGPWVDLRQRSGWSDAKLAAYLLELEREQRAGRRGKPWEQMPYEPQRKKRRRRNVNCLKNTVIWYEDHKNRCPYEPHLSELDPTFGMYTTAVWQCEAGHRYFQDLHSPLKPLSDSENECDNVANGTGARSSDSSEESSSSETEEQHKSHKVQAQQPLAPPANTEGESASGLITQDGIHIPFEHHIENLTSEQGANGNHNSPLNGPETMETVVCVPVPMQMSSGHGTLYENVTQETLGEVVASCPVQGMVQGSQVIIIAGPGYDALTAEGIQLNVTSTGGEELPCAMIEGVAAYTQAEPESGQPSSMESMEYIEIKKENEELFELKKEEPQPLAEIETPCDSEAYHDDEGLEREPEPEDETEGSNMSSIIYEIPKEPEKRRRSKRGRVMDADGLLEMFHCPYEGCTQVYVALSSFQNHVNLVHRKGKTKVCPHPGCGKKFYLSNHLRRHMIIHSGVREFTCETCGKSFKRKNHLEVHRRTHTGETPLQCEICGYQCRQRASLNWHMKKHTSEVQYNFTCEHCGKRFEKLDSVKFHKLKSHPDHKAA