lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate but with a lower catalytic efficiency. The mechanism proceeds via the intermediate compound alpha-D-glucose 1,6-bisphosphate. In vitro, also has a low glucose 1,6-bisphosphate synthase activity which is most probably not physiologically relevant.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MAAPEGSGLGEDARLDQETAQWLRWDKNSLTLEAVKRLIAEGNKEELRKCFGARMEFGTAGLRAAMGPGISRMNDLTIIQTTQGFCRYLEKQFSDLKQKGIVISFDARAHPSSGGSSRRFARLAATTFISQGIPVYLFSDITPTPFVPFTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDKGISQAIEENLEPWPQAWDDSLIDSSPLLHNPSASINNDYFEDLKKYCFHRSVNRETKVKFVHTSVHGVAHSFVQSAFKAFDLVPPEAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKTKARIVLANDPDSDRLAVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNQDRSALKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLIDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVISAELASFLASKNLSLSQQLKAIYVEYGYHITKASYFICHDQDTIKKLFENLRNYDGKNNYPKACGKFEISAIRDLTTGYDDSQPDKKAVLPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYAELCAPPGNSDPEQLKKELNELVSAIEEHFFQPQKYNLQPKAD
The following text describes a protein:
Function:
With MSL1, acts as a negative regulator of salt tolerance.
Miscellaneous:
MISCELLANEOUS: Present with 217 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MPPNSKSKRRKNKSKQHNKKNGNSDPEQSINPTQLVPRMEPELYHTESDYPTSRVIKRAPNGDVIVEPINTDDDKKERTANLTHNKDSMDSASSLAFTLDSHWESLSPEEKKTILRIEKEEVFNVIRNYQDDHSCSCSVCGRRHLAMDQEMERIYNTLYAMDKDKDPETNPIKFHLGIIKELQISKNQQQNDLSSTKGEVVKNFLSSSTVGSLKEEVLHFKQKQLSKQEQAHNETADNTSLLEENLNNIHINKTSSEISANFNSVSDEELQQKYSNFTKTFISSHPKIAEEYVQKMMMYPNIRALTDDLMNSNGQGFLNAIEDFVRDGQIQASKKDDSITEDEASSTDLTDPKEFTTMLHSGKPLTEDEYADLQRNIAERMTNAYDTASKKFKDVSQLEKELFTRFMSGRDKKSFRELIIQSFKNKFDGELGPSVLAATLSSCFSSQSKDTSLDTDSIYEDEDEEDYDDYSEYAEDSEEVSEYEGIEAVEKPEHDEKSNGIRETLHLSYDHDHKRQNHPHHHYHSTSTHSEDELSEEEYISDIELPHDPHKHFHRDDDILDGDEDEPEEEDENEGDDEEDTYDSGLDETDRLEEGRKLIQIAITKLLQSRIMASYHEKQADNNRLKLLQELEEEKRKKREKEEKKQKKREKEKEKKRLQQLAKEEEKRKREEEKERLKKELEEREMRRREAQRKKVEEAKRKKDEERKRRLEEQQRREEMQEKQRKQKEELKRKREEEKKRIREQKRLEQEKLQKEKEEEERQRLIAEDALRKQKLNEEQTSANILSAKPFTENGVGNPVSSQSHPNMTNYQEDNSCSINDEILKMVNSVAASKPVSPTGFNVHDLLLPSTNNQMPAMEQSHLPQPGNQNNHFGTTTIPNALDLATKSSLQTENNYLMNSQTLENTSLLMHNNSSPTKLLPNDFGLSSWGGLTNTMSINPTCKPPVIQTSEMESQAHKSSPQATMPSFGLPNGGTHRKSFTDELNTLTSMLSSSGFADTSLSSSGFPPSQRSVWNDQKSSFSGPSTAGNFNNSSIQSGMLLAPTLGSVESFPNRTSIWDSSTTPMMNKSELSGRNITSTAQDSPAFMASNIWSSNSQYNSPYLTSNVLQSPQISSGVDESHILDSIYNTYLAISPQDSLNPYIAIGTLFQNLVGLNLDYSTFINKLISMQGAYNCEFFTDNNGSITHVRFARQTPAGHSKGLLNQLFSGLNDPTATPFTSRPHTSTRASFPIASSTTQTS
The following text describes a protein:
Function:
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MRDRRPLLRKDAETAATELSMPAETAQERYQHAKKRQAKDMQRGVLSYLLFILVFLGVPLLIVAYCTPFFVLQNLRCRLQEKYFWSDTTVRAMEDGYTRYFNEPPLYPSTEYNRTMMWGTYEPSRIFAVKSRSLKPVTVGIAWYDSAMAHPLRHTMPYLHNKVSAPRSTQKKGIDVEVMQVKWVVNDGLHYAKEVVEDRGNKASLEIELLKSPFADAWHVRIHARVESDSPLVMVVYMSHADTQERIELEAPTEYNDGDWSPVLKSRMQPEGETEHTDFTLRVYDDHSPLHDTAPWHVYGLHTDVEAAFQRKAVDAVGTTPAERAAAGGRGIGGGVHVGDLQQQQLDLRRLPESAFTYIQAKDPQSFRTPPSWTSHNVMILRKSYDSSFRLELSLSPADHAQGNGAPGASATNRIGNLVPRYEALSTCQLTNALRWRSKAISLHSAKIFRPFLSVFNSSKDLYERIATVTLAELFGSLTFTSGHYLHVGADMDDAWDQQGRAKTMWSDAKLQSSRQRVSAIAVVGSRTDEAFGQPSLTGLPLLFLTRWNKEVVKDILASWLLGAQDAETGFVPNRAVFGPETRSFTPQAQRYEHPALASPPTLLLGLQELLKEMSRKSARLATANHRKARNTPEYLERERAADEAFLRAILPALKRWRKWWHHTQCGGATDELARQCRSRKPLEEWPLRPAEDQPESLLVYRWRGRDGHRLPTSGMEDYPRPICAGEHHREAHVDAFSWVALLSTLISRIETEFLHEAESVSLDWEAHLNAVHWDAAEMRYSDRIGCSSWTHSPYFGYANLYPVMLGVVRRDLSRAARTIALAQRELESDYGLMSVSFSSVRLARESGLPHHNMWMGYVWPSANLLFLYGVKSHYLEALDSTSAAAGGLTEARLRDFYTSLRVNIIEAIRGGSRWWEYYSPLDGRGEGSKTHVATRSLLLGLLDDFA
The following text describes a protein:
Function:
Enzyme of the diterpenoid metabolism involved in the biosynthesis of antibacterial oryzalides such as phytocassane.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MEDKLILDLCLSALFVVVLSKLVSSAMKPRLNLPPGPWTLPLIGSLHHLVMTKSPQTHRSLRALSEKHGPIMQLWMGEVPAVVVSSPAVAEEVLKHQDLRFADRHLTATTEEVFFGGRDVIFGPYSERWRHLRKICMQELLTAARVRSFQGVREREVARLVRELAADAGAGGDAGVNLNERISKLANDIVMVSSVGGRCSHRDEFLDALEVAKKQITWLSVADLFPSSKLARMVAVAPRKGLASRKRMELVIRRIIQERKDQLMDDSAAGAGEAAAGKDCFLDVLLRLQKEGGTPVPVTDEIIVVLLFDMISGASETSPTVLIWTLAELMRNPRIMAKAQAEVRQAVAGKTTITEDDIVGLSYLKMVIKETLRLHPPAPLLNPRKCRETSQVMGYDIPKGTSVFVNMWAICRDSRYWEDPEEYKPERFENNSVDYKGNNFEFLPFGSGRRICPGINLGVANLELPLASLLYHFDWKLPNGMAPKDLDMHETSGMVAAKLITLNICPITHIAPSSA
The following text describes a protein:
Function:
Part of a type III secretion system.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSEKTEQPTEKKLRDGRKEGQVVKSIEITSLFQLIALYLYFHFFTEKMILILIESITFTLQLVNKPFSYALTQLSHALIESLTSALLFLGAGVIVATVGSVFLQVGVVIASKAIGFKSEHINPVSNFKQIFSLHSVVELCKSSLKVIMLSLIFAFFFYYYASTFRALPYCGLACGVLVVSSLIKWLWVGVMVFYIVVGILDYSFQYYKIRKDLKMSKDDVKQEHKDLEGDPQMKTRRREMQSEIQSGSLAQSVKQSVAVVRNPTHIAVCLGYHPTDMPIPRVLEKGSDAQANYIVNIAERNCIPVVENVELARSLFFEVERGDKIPETLFEPVAALLRMVMKIDYAHSTETP
The following text describes a protein:
Function:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MAFNLLENVKKYVHEGNDSILAEKYREIYDVGQVAVLNGLIDYFSSNIETHFELSQLEQLYSLCANFHELPSASKNKIVDLVSSIILSESSLLEELISQNRTDFSVPQENLEAFGIAFTLIVNALSKNNQLNIVGNLSSAKDRKKDVGNNGKGWAGSAHVCSCLDAIYSLLQKRLSRAWITNSEKEMFLSMFLRPTYLFMESEVNMKLVPLRTRIFKVIALAVKSHDHGSAAQTTIIQQLQYFEHLPEHLAELLHITTDQYAEEDLIQSVLCELCSLQFNNNDTKGPKHISAFLIRLSALNPRPCLKQLTQLVKFLGTESYTLRCAVMEVVGNILLDLLKVEGSEAELVSANINSLLDLLKERMLDINPYCRSKILQTYLRVFELPIKYPQRRQEVAEISCICLQDRSSNVRRNSIKLISKLLATHPFSAMYNGLLKREQWEQGLEAINKQLDVLKPDTSILNSEQEVDESLLEDATIIQEEGTANSPKTSNAASASATRIEEADLAKDDLLKLQLTKQFYLDALKFITTVEKSSTLIGQLMGAKNKSEVIDVMDFFVFAESFGISNASAYIKKMIHLIWVKGTSEEGNSIQNHLIECYSVLFFNPPPQVSSNDAANYTARNLITLTYNSSLAELTSLEQMLCILMQRNFFVKLVINKLWQVYGYLRKEISRTQRRGAIIVLSMLALGNSEVVLQGLDLLVQVGLSEPGFKDLILARYTCTAIKRIGGKKNNKRASLPNSHLICQKLAQLLCRPIDTDDWYALAEQAVDAIYAVSQHPDELSTEIINKFTGMVFSRFSNPKSNDMDEDKDEVEEIPAFSPTRQLAHLLFLVGHIGIKQLVYIESFEAEFKLRKAELDKGPSDDDQMNVDKSEPSEFDMIAGTSEDDFTDAMTYIRERELLYGENSLLARFSPLVVELCSKNTTYSNKHVLAAASLTLTKFMCISQSFCAKHLPLLITILEKSDNSLVRNNLVIGLADLTMCFNQYIDQNSEYLYRRLSDDEPSVKKTCFMTLAFLILAGQIKIKGQLGIMARCLEDKDPRVSSLAHMFFSELSAKDNAVYNNFIDIFSVLSKSAEELDADDSMFKRIIKFLMSFIEKEKFTRQLAERLASRLNKCSSKRQWDQVVYALSLLPHKLENIQKQIADGYRY
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Miscellaneous:
MISCELLANEOUS: [Isoform Short]: Lacks the C-terminal transmembrane domain, but has an ER retention motif at its extreme C-terminus.
Subcellular Localization:
[Isoform Long]: Membrane; Single-pass membrane protein; [Isoform Short]: Endoplasmic reticulum lumen.
Sequence:
MFSLRRLLLAATLFLGAMLLFAQSAEAAKGPKITHKVYFDIEQGDKPLGRIVMGLYGKTVPKTAENFRALATGEKGFGYEGSTFHRVIKQFMIQGGDFTKGDGTGGKSIYGDKFPDENFKLKHSKKGLLSMANAGKDTNGSQFFITTVITSWLDGKHVVFGEVLEGYDVVEKIENTKTGPRDAPAEPIKIAKSGELEVPPEGLEGQSEWASPAYANEDEKPAAPVPVTDAKPPAHDSIPAATADDDDTGAPLFAKVLFFGVLVLGLVLYIRLRRAPKGTYGKGME
The following text describes a protein:
Function:
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
Subcellular Localization:
Cytoplasm, cytosol. Peroxisome membrane.
Sequence:
MELHVQLKHSTDCFVSLPPKIVHSLLLLSEKQSKSLGTLGLEITWYDKINKKENKGYVGWAGGSTDPRFTDSIEMSQEMAQCLGGIKNEQKLKLKALNNIELAHSVQVEPLTSDDWEIMEVHQQYLEEQLLNQVNILYSGQIVPIWIHHKTIIKLKVTETLPTPVVKLSSNSEIIVAPKPRNLPTTTTSSQQQQISKETLKPRFLQIKDFKIDYNNNNTFINEIYINKELLNQFQWNIGDIIEISKVSKNNNKNNKKEKNNNGGDEEEDDDDNEEFDDDDDDDNNNNEDDTSKLQKQLDNKNNNNKKNKKNNKTIYARVFINDKSNNQQVLIHRNIRTIGNFYINTIVRLKYTTSHSLPICPIGSILVKQVIWKQNSLSNLIKQQSSQKIYSVEQIKEQIKVWSNNNLSNNQRYPLLNGSIVSINSNLDLSFNFNNLTSSIIPPTSSSSSSPSNNLDSQRSNNNNNNINNDQLNDITNNMNNPYLSSIQQIGDIMSNLNTNNNQNNQNNNSNKLMNQFQMNNGIFMLSLEILSNDKLLKIESGGNNSIEKKKSLEDYNEIGDRLFQRIGGMEKQIKQAKEFLSLYMYKDLSVIREQLNTPGVNGMIIAGSHGSGKSLLATSLGGYYSTDSRSNAFIIKLDCNQLKELKVENIRKQFNKLFYKSCKESGNTLSATTSTNTTPPPIIIILESLDLILGTPNDQDPGSKIRCEQLVSHIKSLCFKYQNRSSPIVMIATVISSQSLCQSIQIPELFGLTIELQAPTREERVEILERYLKYQGKQLKDQQSLNLMKFSASMEGYLGCDVEQIVDRSIHLSSIKEIENNNNNNDDNDDDNIIEFSIIEKAKEGYTPITLKGIKLHSSEIKWQDIGGLDSVRAMLKETIEWPTKYPKLFQSSPLRLRSGILLYGPTGCGKTLLASAIAGECGLNFISVKGPELLNKYIGSSEQGVRDVFSRASSAKPCVLFFDEFDSIAPRRGHDNSGVTDRVVNQFLTQLDGVEGLTGVYVLAATSRPDLIDPALLRPGRLDKSLYCNIPEFNERLDILTCLKSKMNLSPSISLEQLSTNTQYYTGADLRALMYNAQLKSIHEWMNHLEEEKKRKRKEKEDQSNKNSSQQQDDFIIFQPKNNDNSISKSNLTFEEKTNLQKQIDTIKSQFINSNTSTLNKSNLSNEQPPLITQSHIDLALKESSPSISESERKKYERIYNNFLKERGSVTGNKKEGVPKQTLA
The following text describes a protein:
Function:
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm.
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side.
Domain:
The FG repeats are interaction sites for karyopherins (importins, exportins) and form probably an affinity gradient, guiding the transport proteins unidirectionally with their cargo through the NPC.
Sequence:
MPVCNFFLQGRCRYGDTCWNEHPTGGRGGDYRGNQQPSNRGGFGNRVWINPSQRGGGGSSSAGGSNEWGRGAASARDVQSSEFSFSQNRFSALETQRAGAEDTHTTLDTIQKEMEVWQTSGQWPFSCYSAVNRQISGFIELCPEELRLEYYTSRASGDIQPYINSVQQLANQWRSRVQELRNMSSSTQISVIAELKSSSPPASAPGFGSPGPGFGSATSGFGNTSLSSPPAGFGGAGFGSGPQSSSTFSFAQSKTDFGASNTQQASGFGSSAFAQPSSGFGNPAPSAASFSFAAADSESKPSAGGFGSASGFSFKTATAGQGSGFGSGFGSSSGFGSSSGFGSSSGFGSAFGSAAPAQSSSFGSTGGAADTQSGHGLFTANSELTPEELKEFMAKRFTLGQIPLRPPPADLLMI
The following text describes a protein:
Function:
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
Subcellular Localization:
Cytoplasm.
Sequence:
MAVEKFETALKKLEDVVRKLEGGDLSLDDSLKAFEEGVKMASFCTKKLDEAEKKVELLLKKKDGTFVREDFRLDDE
The following text describes a protein:
Function:
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Sequence:
MAKVIEKFFIASMLMWAVPVAILIAFNKNLFPGSADMSPYSLTLLSGFLAVISVNIVIAFYIHLAMKEPSEKHEPDPKFVSEAEAGVKHLVKSESSSTNKKDECVLKNVSHGQVDNGNQCWGHLGYARLNRLMHTVSFCWRTPFNMHFIAPLIKFKIKV
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MSEHSSPAIAAVVFFVGFFLVFLCIECSPAPVAGGRRHHQTPHAHPLTHEYYSNTCPQLDHLVSLVTSQQFREFPISAPATIRLFFHDCFVEGCDGSILISSERGGLLVEREAADNKNLAPEAFDTVNKAKELVEKKCPGVVSCADILAVAARDFVHLAGGPYYKVKTGRKDSKVSLHYKVQFNLPRPNSTVEELLLLFSKKGLGKDDLVALSGAHTIGFSHCNHFLSRLYNYHGTNRPDPSIEPRMLKELQMLCPPFGGSADVVAPFDVQTPFEFDHMYYRNLEAKMGLLATDQALWLDRRTRPLVLKLGQDKVKFFQAFALGMEKMGAIGVKKGRSGEVRKLCYRPN
The following text describes a protein:
Function:
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein.
Sequence:
MVGRNSAIAAGVCGALFIGYCIYFDRKRRSDPNFKNRLRERRKKQKLAKERAGLSKLPDLKDAEAVQKFFLEEIQLGEELLAQAEYEKGVDHLTNAIAVCGQPQQLLQVLQQTLPPPVFQMLLTKLPTISQRIATSVFWKQSRRHVEGEQLVPTGTSLRSKIHVAQPFLCYIRKWTELRWPFRLSCGRGGIFLKPEPVSLRRVTHKTRPREVEHVY
The following text describes a protein:
Function:
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Sequence:
MERLTRWLLVMMAMLLAASGLVWFYNSNHLPVKQVSLKGNLVYSDKKTLGSLAKEYIHGNILRTDINGAQEAYRRYPWIASVMVRRRFPDTVEVVLTERKPVARWGDHALVDGEGNVFEARLDRPGMPVFRGAEGTSAEMLRRYDEFSTVLAKQGLGIKEMTYTARSAWIVVLDNGITVRLGRENEMKRLRLFTEAWQHLLRKNKNRLSYVDMRYKDGFSVRYASDGLPEKESEE
The following text describes a protein:
Function:
Glutamate-gated receptor that probably acts as non-selective cation channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRLLVGAGILSLLTFLNTRPSVTAALPPPVRVGLVVDLTSDVGRKSLTCLCMALDDFYQKHPDYATRVELRLNDSHGDLVTSAHASEELMDKNGQLQAIISPQTSPEAAELITGTAEHSNIPILSSSATSPASSSSSRSRFFVSTAPNISSQAAPIASIFKVFAWSAAVLLHEDSPYGVGILSALVHAFQGSPGLTDSVAVPGDATDSRLDAALLALKTMPTKVYVVHMPPALAARLFRRAGVAGMMSEGYVWIATAGVGNVADSLPNPGDIDYMQGVVSLRPYVQATDRVRSFWRRFKMRFQQENPGVEQDEPVTLLWLYDTAWAAAAAAEASFRTAQPTALIDALLVTKFDGLAGRFGLVDGQIQVSVYEIVNIIGNGARTVGFWTPELGISTSLHPKVENTASTDSASKELKVILWPGETAAIPIGWNFASRRPGGLRVAVPVKGGLGQFVKISSDPAIAGDRVSGYCIDVFKAVMTRLGYPVDHLYVLADGIKIYDALVNMVHDKKFDVVVGDVTISSSRMKLVSFTMPFTETGWSMIMAEKGGSGSMWIFTSPMTLELWLTILAFFFFTGFVVWAIEHRINPRFGGTPQKQLGVLFYFAFSTMVFSHKEKLESNLSKLVVIMWVFVVLILTTSYTANLTSVLTIQQLQPAISEWTDRDYVGVQENSFIEDILREMGFDEARFRRYSSIDEYADALNRGSDNGGVTAIFDEVPYLRLFLSRYCRGYSMVGPTNKSGGFGFMFPKGSPLVGDMSRAILELAEDGVLTRIENKWFSHPGSCVGNNGGSNARLGLWRFRGLFLINGVVSCLMLLIHLARFVYQERARGQVKANTAGVLPWLCAWLRRYCAFEGQRGGEPVSDGRAAVELNHMQDSAAEEAAQQEGAMGDSYSTHVDATDF
The following text describes a protein:
Function:
Negative regulator of the mTORC1 and mTORC2 complexes: inhibits the protein kinase activity of MTOR, thereby inactivating both complexes. DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy. In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity.
Subcellular Localization:
Lysosome membrane. Note=Localizes to the lysosomal membrane when associated with the mTORC1 and mTORC2 complexes.
Sequence:
MEEGSSGGSGSSDSNAGGSGGVQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTYPNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKDDGTFALDSEVKAFMRGQRLYEKLMSPETTLLQPREEEGVKYERTFMASEFLDWLVQEGEATTRKEAEQLCHRLMDHGIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLMELLNETSPSSQETHDSPFCLRKQSHDSRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSPPVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGPAAAAGMKVCQFVVSVNGLNVLNVDYRTVSNLILTGPRTIVMEVMEELDC
The following text describes a protein:
Function:
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54.
Sequence:
MSFSVEVLAGIAIELQRGIGHQDRFQRLITTLRQVLACDASALLRYESRQFIPLAIDGLAQDVLGRRFTLEGHPRLEAIARAGDVVRFPADSDLPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDAMTPEQFEVFSDEELRLVAALAAGALSNALLIEQLESQNMLPGSSGVFEPIKETHMIGLSPAMTQLKKEIEIVAGSDLNVLIGGETGTGKELVAKAIHQGSPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLFVPPLRERGDDVVLLAGYFCEQCRLRLGLSRVVLSPGARRHLLNYGWPGNVRELEHAIHRAVVLARATRAGDEVILEAQHFALSEDVLPAPPAESFLALPTCRNLRESTENFQREMIRQALAQNNHNWAASARALETDVANLHRLAKRLGLKD
The following text describes a protein:
Function:
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
Subcellular Localization:
Cytoplasm.
Domain:
Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
Sequence:
MKPKSVSEIREIFLNYFKDKSHNVVPSSSLLPAGDPTLLFTTAGMVQFKPLFTGAVELPYTRATSCQKCLRTTDLEVVGKTERHCTFFEMLGNFSFGDYFKEEAIEYALDCSVNHFGFDKNKIWVTVYTDDDEAEKIWLSKGIPKERITRLGKKDNFWGPAGDSGACGPCSELYLDRGIEKGGPNCATSGTCKPGCDCDRFLEFWNIVFNQFNQDTEGNLHPLKQTGIDTGSGLERVALLLQEVDSVYDTNELRKIISFYEELSGISYEDKTLSEISEKKNNNQQISSQVRNETKSIQDSRKTAFRVVTDHIRSVLFSIGDGIYPDRTGRGYVIRRLIRRATLFGRKLNFKEPFLYKLVDKVIEIYKARYPELQRNAAAITKTILVEEELFLKTLELGLEKIESLVQKTKAGGKTIFSGADAFLLYGTYGFPAEMTEEIVAEQGLDFDKKGFQEELEKDRQFSRESWKVNKVSLMTGLNVDKTEFLGYSSVSGKGNITHLFYNSPKSSNSLSQVDSKLQSSTPAGTGSYDSKQVSSLKEGQAGAIVLNKTPFYPEGGGQVGDIGFLRQGKNVFKVFDTQKENDSIIHFGEVLSGEFIVSQELEAEVEITRRERLKFHHSGTHLLNGALRTLLGDHVLQKGSIVSPEYLRFDFSHPSSLTSEEIRQIESWVNESIRKNFPVETKELSIEDAKKTGAVATFGEKYGERVRVVQMGDASIEFCGGTHVSRTGEIGYFFIKKESSPGAGNRRIEGVCGPAVIETFQNRFSELTESVQNLNLKIKSELGEEGTKILILSFIPGPDEIREKLEKEGASAVSFFRDLSENIATKIEENTSSFLKIKKNLAERDFENNTSVIENVLASSVDTGIGKIVSAIFEDKDPNSLKGLSDNLKVREKNLLVILGSRNSENASIVITCSSELTLKGIHCGNLIKTACELLGGKGGGRPDMAQGGGKEKQNLESAIAGVINEAKQILTGERV
The following text describes a protein:
Function:
Polynucleotide 5'-kinase involved in rRNA processing.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSDDFVVPTYEVGGSDSGSDQDISDIEEGSFNGISATPLPTADVEYVSEASPMDATASLGYLSGAEGANLYVAREGANYFNDAANKAVVLCLHSYEQLAISGVFKLQVMKGGITYNSIHYNCGLHTYDFWHPLSESIPPIAASFAADWEEHSYGLSPWLPADIKEEYECILRISEGSNIGDVGRLMAELGQLWTRHTGCTFSILRPEDYARPLILNKDWDNLQAELMIHHMNSEHDMRVMCIGGKNSGKSTLLRLLLQKFLHGNKSTTKATGVSHEADVVNYLDMDPGQPEYSAPDSISWSKLTSETLSLGQHLAQGHREMIQTTYIGSSTPQTWPEMYLTAMEHIIHKWEMEGQMNTALLNLPGWIKGFGITIINKAMELFKPTHIIFLTHGGKLISKELVVPNMFETMQKGKYKPMIYNLQAFTQHNIPGLPAQDPRYHAANIRSFRLLAHLHRLSEQSYYPGPLLSSPPLQVSFGSQGIMAFRFLQDPSSGYHQDDISAALQGCVVCLYHSKMPPDIDMCGVFPMLKHSADYTSMDFVTLALIHSIDVERKFMNIYIPGHVSGRVHSLKNNFVLVRGATDLPLCELYPQKLLSSSYRNREIPYVSFSKRKKYEYVWKIRKNVRRRGHYNK
The following text describes a protein:
Function:
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Sequence:
MLVRKLTLIGAALARAALALQQEDFVVNGELLPGVREIDRAEVPEMHAGLMPLEEDEDGRALFFWRMGEQCGKRCSNELIVWLNGGPGCSSMDGALMETGAFRVAEDGKLYLNSGSWHTRGTMLFVDQPVGTGFSRPGRDGRLRTELSQLADDFLLFMERYYAVFPEDRRRTLVLAGESYAGQYLPYFADAVVRRNAERAPEERYKLQNVMIGNGWVDPDLQSLSYVPFVSSRGLFGPETRNFQDILRDQEACQNAINHGPAKGFSHPECEGILPKLLSSIPGPDRPVQQCINMYDIRLRDVFPSCGMNWPADLPNVHKFFGTPGVLEALHVDPQVAGPWVECKSAVSEALVNAHSRPSVHLIPGLIEAGVKFVFFNGDQDVICNNMGVEMLIAELRWRGHMGFSNATENFDWYHSDADAKTLVAAGVVKRDGPVTFISVFNASHMVPFDVPRISRGIIDIERSATILGVKGDSRMLITVDTEEDVTLSTNAERNQQIRHNQLKRLNGDTRKFTIAVFGLTISSIIGVIVYFSMRLHYGAKIRAILTNPKSGTSSADDFSMDDEYTGTVMGDFHHGTHKKGQYYAVPDTDISSSELHSV
The following text describes a protein:
Function:
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MPPASDSAKATTAAPPTPPLTSYRDSALGIFALLLAFRIANALTLRTFFQPDEFFQSLEPAWQLAFGEESNAWITWVNASLDHLHVPVVGFYRISAKLADICGLTLPAKAELLLVTPKVTQAVFAALLDCYTWKLAEKAYGRGSRTGTVTLALSVCSPWQWFCSTRTLSNCIETTITTVAIYHWPWHWPGTARDSTTAGKDQSQSVEKHLGSPAKLRLSLLLAALACILRPTNALIWVSVFVPTLWQATKRQRSAVLACSVASDRLYYGIWTLPPLRFLYFNIAQSLAVFYGKNRADYYFTEGVPLLLTTVLPLGLIGLVRALRGKELRHSPITGSPSIHSPAPEYIHDAAQRRVLIRLAWTCVVTIVALSLISHKEVRFLYPLLPFLHILAAGPLSTTFPANGPFTRKALLISLLLTNILLATFTSRIHQRGVIDVLDHIRHKHEARNNLSTLTQPPSSLSNTTVAFLMPCHSTPWRSHLIYPEISAWALTCEPPLNTPLSDRSSYLDEADEFYIKPGPAVWLRDNMESLDTIQAGGSRSGRHWIRQDPKLKAKYRRAWPQNLVFFEQLEGVLGQVLGGSRYRECWRGPNSWMHDDWRRKGDVVVWCLDGE
The following text describes a protein:
Function:
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MAGKKLKKGKSGNAAQYITRTQAVRKLQLRLSEFRRLCILKGVHPREPKKKPKGANKTYYHLKDINWLAHEPLLNTFRSIKAHDKKVRKARAKQNKELAKRLAALTPTYRLDHLVKERYPSFVDALRDLDDSLTMVHLFATLPAESKYDIPQRTVQLCRRLALEWQAYVVRSGALRRVFVSVKGYYFQAEILGQSVTWLVPHALSQVLPPDVDYKVMLTFLEFYNTLLQFVNFKLYHNLGLRYPPVLDPRLEEAAAELAAIMKDIAGMRDAAEGDRAAEAAAIAAADGDEAAAEAAAAAADPTMRARIDSLQTRLREIVGTGKGAAAGEEEDGKDGDEEEEEPEEVDSEAGDEDDDDLPVLDSGGEDEEEDEEDDEEEAAAAQRNTAAARSGGRASTSAVALLGEDDEDEDDDMPLARVTADADADVDAGTRAAGGACGPGVDPSDEAAVCGSLFRGRVFFLGREVPREPLMLVIRAFGGVAAWDGDGSPHAETDEAVTHQIVDRPKQGHKFLSREYVQPQWVFDSANFRVLMPTDLYAPGTVPPPHLSPFVGEADEDGYTPDFAKTVRRLQDAANAARLRAAGLALKGADGSEFVGEGADGAAAADGEGAAGEDLAAAERQYASELAKEVKQAAKRKRGEEAAAEEEDDEEDEDEEASGSEDGEDDDDDDEEEEDEEEEERPAKKSKPAGKGKGGAGKDEDEEAAMADIMMTRKARKMYNNMKQKEAAKQERVQQLESKKAKLAATGAAGPMGQVKPAAAGKAAAAKAAAPAKVAASGGKGAAAKGKEAPAPAKGKGTPAAKGKEAPAPAKGKGAAAAKEAPAKGGKDAAPAKRQRR
The following text describes a protein:
Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex (By similarity).
Subcellular Localization:
Cytoplasm. Endosome. Late endosome membrane; Peripheral membrane protein.
Sequence:
MSDHAINEHPSRILNTIEKIRFWKNGLAEELELLFRKQCEDTFTLQAINIEVDTQDENKIEEVRIYLSTPAFDKTILTSACITVRSYYPSQPPIVQLLDEKGGKHKYTSLLLQLWKNERSVFNIYRLVQALIKQDFEREHTSPPELPTKLVNTIEKLKVKEENEAPPVIPAKPFSSSSEQHFRKVPALPSKLPPKPLKITANSSLGQETNSNSSSFQSTLFSLNTAPFSATSQQLVHDSVSLRRPSSNIPAQKPIPPKPEQNEIIITKDTPSLKDKYSKPALLPQKPKVSKGQIVQQVSVFSTGKKIESQSLLNLIDTDIETPLKGSSELLYSEDFKPNVDPVKIQQILHKQNKIIEEKWISQIRISKNLEVKQRLLDQERHALETLAKNIENNRFILGKRRRKAREALQKLDNLKDLSVQELFIIPSERELKYYELKRKDEKLDEGIRALNQALHHESIMPASWLKGIKLLARQQFLIRDEMLQYS