lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in fat storage.
Subcellular Localization:
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Sequence:
MGALSKLAHSLGQPILTATCYETIHTWNPDCNGAFFDALPVGLIFSLKTYASFYLITNVVSKRGRLDKINWKKFGIDVCQSSLFLVTNMCFFLILLCKFRKWLGFFTPITMGLVSSILASGIAILVEKKSRRPALALYLINLASETYYRHLANHGYVTMHTYGECIPFGIGLMLFTWLQSIGRLPKSFNGFMNVALKSNVSENLINEKKIPDNFRLFLEKLRSDYKKTELCNHPHSCVSHSVESFAKNMTFGLTASSVLTVIRNVRTIIKNPLNLITLLVSKENLKLPLFAGFLPFIFNATRCSLNRVKYVPPVLNNVFSAGLASVAMAFYPTVSIAMYCLWKAIETVYFDLVDRGYLPKFKNGEVILYAITTGYVLWNAVVEPRAIRRGYLNFLFGLVGGKISLFNRRLYDHFGFVSRDVYTKIPEFDPKYAMINPMLYMPLVE
The following text describes a protein:
Function:
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MWRTNQVSSRQNMAGFTLIEVLVAIAIFASLSVGAYQVLNQVQRSNEISAERTARLAELQRAMVIMDADFRQMALRQFRTDGEAPSEQILQWKESLLDSDQHGLLFVRLGWHNPQQQFPRGEVAKVGYRLFENRLERVWWRYPDTPAGQQGLISPLLTGVEDWAVQFYLQGEWSKEWVPTNALPEAVKVTLRLKDYGEIERIYLTGGGSLNMTQESVENAG
The following text describes a protein:
Function:
Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MAEPLAVETKPLSNGNANGNAVGIAESASAVFQEKLKLQQQEESNEIAAVPKYGLKLKFDHVWPEKRIQNVRASIRQTLPMVPLVCRYAAYYWKVSREGRRVYMDYYYMENGKQIYGVPIGGIGGGTIGRGYAGEFCRFQMRPGIYEYNVVLANQFIVTIKDPKGCTIFQSLLSKCSTRDKTSDPDGDPDGERTKCQLPNCSSRAKQPLSAWHSNIEDTRCSYTGLYPRSWTEYDLSHYGVRLTCRQVSPVIPHEYRESSLPCAVFVWSVENVCDQERKVSITFTFKNGTGNKKQDAEGGAESQLISEGNAKGVSIRQKISEMPCSYNLACRVLPEISITRCPQFDPAGNGEQLWAQLKEHGQLSEHPTSEALKTKDIGVAVCGQVALKPMASHDLEFVLAWDMPKIQFPRKMQTHTRYYTKYFDDSGDSGPRICEYALRQYSTWERLIDAWQRPILNDETLPDWYKCAIFNQLYFISDGGTIWLKCDSSLGKELAYDDPRLAYGRFGYLEGHEYRMYNTYDVHFYASPALAHLWPNLQVSLQYDFKDAIAAELNDTRKMLYDGKVMPRKVKNCVPHDLGDPDEEPFTLINCYNIHDVNDWKDLNTKFVLQVYRDYYVLNELAQAQSDNASKFSSIEFIDKESLYELYSQDNKRKNSADEKQQNRKSASMYINETNGKVYLMDAIGYLKAMYASCKAIMERTIEYDKDNDGLIENTKMPDQTYDSWVMDGPSAYCSGLWLAALQAMSAMATILDQPNDCLRYQDILEKGKRSLEEKLWNGSYYRFDLSHSHRDTIMADQLCGHWYLKSCGFDYEIYPKENVRTALKRIYDNNVMGFHEGNIGAANGFIANASEPTKPGHVDNSNIQAEEVWPGVVYALAATMIQEGMFEEAFQTAGGMYKTLSQRIGMNFETPEALYGEKRYRSIGYMRPLSIWSMQVALERRRAQRD
The following text describes a protein:
Function:
Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
Sequence:
MDPSPQSTPPTGDDPAAAADPDLPRLTVTQVEQMKVEARVGDIYRSLFGAAPNTKSIMLELWRDQHIEYLTPGLRHMGPAFHVLDANRPWLCYWMVHPLALLDEALDDDLENDIIDFLARCQDKDGGYSGGPGQLPHLATTYAAVNTLVTIGSERALSSINRGNLYNFMLQMKDVSGAFRMHDGGEIDVRASYTAISVASLVNILDFKLAKGVGDYIARCQTYEGGIAGEPYAEAHGGYTFCGLAALILLNEAEKVDLPSLIGWVAFRQGVECGFQGRTNKLVDGCYSFWQGAAIAFTQKLITIVDKQLKSSYSCKRPSGEDACSTSSYGCTAKKSSSAVDYAKFGFDFIQQSNQIGPLFHNIALQQYILLCSQVLEGGLRDKPGKNRDHYHSCYCLSGLAVSQYSAMTDTGSCPLPQHVLGPYSNLLEPIHPLYNVVLDKYHTAYEFFSEE
The following text describes a protein:
Function:
Has a dual role in the assembly of cytochrome oxidase subunit 1 (COX1). It has a regulative function on COX1 synthesis, acting as a translational activator specific for the COX1 mRNA, and it also binds to newly synthesized COX1 protein. Together with COX14, may act as a chaperone that binds efficiently unassembled COX1 and prevents it from unproductive aggregation. When bound to COX1, MSS51 is unable to interact with the COX1 mRNA and translation is halted. This may be a feedback control that ensures that COX1 is only produced as long as potentially harmful assembly intermediates are not accumulating.
Miscellaneous:
MISCELLANEOUS: Present with 4800 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MTVLYAPSGATQLYFHLLRKSPHNRLVVSHQTRRHLMGFVRNALGLDPPPSPEDPTPENRFHPWDQSPSVDLRERAAKIRTLAHCPVTGKDINYTCPLSGIPTHHSREAWEMDKAYHDSKKYEILKKVNIYEHDLRSGRPFPEFDFPQQQGYDKAVNLTNWDLFFYTRSFYSMDTEFQLAAVTKMLSYPITIGSLLHKFSPYSLNPKGPITLEGLKSLAALRYTLYPLENRSLPTTTKNRAMRIFILGARAEAQLPGHVWKQLQFLFPEQSFEIHFIGPECLYKRDKQEYVKSTTPVVQRVDETLKFIYRTNFFEVFHEAQDFFPYDPYMDVFFTFHPGYASPESHGSWMGETMKALLETKCAIFTTGFNKKDLTDDINLVKSKYGKEMDVLMEPVRNVFGSTKWELNDMNPQEVYQFNMYIAGFRGKRYHTIKRQ
The following text describes a protein:
Function:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
AMLSRALLFPRLGQLSTRSLHTSVSAPSGHHIEHWWGPEKAAGRDVVGYGSNGDEAYQDRLDYWYPAIRFRKEDDISKALRIKEKSDWKTLSAEDKKTLYRYSFRQTLSEFEAPTGYWKVMVAATALVISLATFYAVFLNVYVYPVVPPTFQNEYKEAQVQRQIVLEKGAFLGPAKYWDYENNQWKK
The following text describes a protein:
Function:
Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MHPQLDKNRFNTCDKLMDALEECHRQEFLKQCLGMCNFEKEQLIQCLHYQRVEDSKLRILETREKRKNWELKKKQAEEEAYGKNGYLKKVLEAEAASKK
The following text describes a protein:
Function:
Has high processivity, a high polymerization rate and high fidelity. In addition to polymerase activity, also exhibits 3' to 5' exonuclease activity; Intein encoded endonucleases are thought to mediate intein mobility by site-specific recombination initiated by endonuclease cleavage at the 'homing site' in genes that lack the intein (Probable). Upon expression in E.coli PI-PkoI recognizes the minimal sequence 5'-GATTTTAGATCCCTGTACC-3' and cuts after T-10. PI-PkoII recognizes the minimal sequence 5'-CAGCTACTACGGTTAC-3' and cuts after C-10. Given the high intracellular K(+) content (>0.5 M), PI-PkoII is probably more active than PI-PkoI in vivo.
Sequence:
MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEEVKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKIREHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFDIETLYHEGEEFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKEKDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWETGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENIVYLDFRCHPADTKVVVKGKGIINISEVQEGDYVLGIDGWQRVRKVWEYDYKGELVNINGLKCTPNHKLPVVTKNERQTRIRDSLAKSFLTKKVKGKIITTPLFYEIGRATSENIPEEEVLKGELAGILLAEGTLLRKDVEYFDSSRKKRRISHQYRVEITIGKDEEEFRDRITYIFERLFGITPSISEKKGTNAVTLKVAKKNVYLKVKEIMDNIESLHAPSVLRGFFEGDGSVNRVRRSIVATQGTKNEWKIKLVSKLLSQLGIPHQTYTYQYQENGKDRSRYILEITGKDGLILFQTLIGFISERKNALLNKAISQREMNNLENNGFYRLSEFNVSTEYYEGKVYDLTLEGTPYYFANGILTHNSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIPSLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRAIKILANSILPEEWLPVLEEGEVHFVRIGELIDRMMEENAGKVKREGETEVLEVSGLEVPSFNRRTKKAELKRVKALIRHDYSGKVYTIRLKSGRRIKITSGHSLFSVRNGELVEVTGDELKPGDLVAVPRRLELPERNHVLNLVELLLGTPEEETLDIVMTIPVKGKKNFFKGMLRTLRWIFGEEKRPRTARRYLRHLEDLGYVRLKKIGYEVLDWDSLKNYRRLYEALVENVRYNGNKREYLVEFNSIRDAVGIMPLKELKEWKIGTLNGFRMSPLIEVDESLAKLLGYYVSEGYARKQRNPKNGWSYSVKLYNEDPEVLDDMERLASRFFGKVRRGRNYVEIPKKIGYLLFENMCGVLAENKRIPEFVFTSPKGVRLAFLEGYFIGDGDVHPNKRLRLSTKSELLANQLVLLLNSVGVSAVKLGHDSGVYRVYINEELPFVKLDKKKNAYYSHVIPKEVLSEVFGKVFQKNVSPQTFRKMVEDGRLDPEKAQRLSWLIEGDVVLDRVESVDVEDYDGYVYDLSVEDNENFLVGFGLVYAHNSYYGYYGYARARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPGADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGYRKEDLRYQKTRQVGLSAWLKPKGT
The following text describes a protein:
Function:
Not required for motility.
Sequence:
MLKGLYTATSAMIAQQRRTEMLSNNIANANTSGYKADQGSMRAFPEMLLSRIESKSPAGTSRTEIGSVNTGVYMQELKPLFTQGSLKSTDQPTDIALIENQVPMSAETNEKAALFYPVQTADGIRYSKSSTFSLNENNQLTINGRPILSTDRQPITVDNENFTVSENGTVTTNGRTAGQIDVRMAEDVRNLKRDGNDLYSTADGNDLPSAAGNNQVAYSLKQGVSELSNVDVTSAYTEMTEAYRSFEANQKVIQAYDKSMDKAANEIGKI
The following text describes a protein:
Function:
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
Subcellular Localization:
Cytoplasm.
Sequence:
MRIRIRGPSGQFAITLAEDATVGDLRNTIIEKTGLTAYDAKYGYPPKPISLEHAETDQKLVELGIQLDREQLIISAKDGPPGPSGKKEDTSSYAGQSSPKLSLSRKQNPVAEDTPKVPSPEHGGLFVLRVMPDDNSCLFRAISTALLPGEDTMVELRSAVAETIQNNPDEYSSAVLEQPPDDYCRWIKNETSWGGAIEISILSKHFDVEICSIDLGNLRVDRFNEGQSRRCFLVYSGIHYDTITLSPGENVPPEFDTTVFNASDSLALEKALAVCKLLQERNYYTDVAAFRLHCNDCGAILVGQQGAKGHTTQTGHRDFSQVS
The following text describes a protein:
Function:
Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.
Sequence:
MSEDIEFVQEKHIQYLESYTTIKNAEELIFNETLKMCGVFYFLCSCKILSHTIEKKEEFINFILKCQNVDGGFGNNINYDSHIVSTHHAILSLLLLNYSFDKINEYMDKANNHHDINNTNDNNKVDLNNTNNNNKLDFNNTNDNNYNVYSKSIRENTCKYILTLFNEDGSFKGDMWGEVDTRFVYSAVSCLTILNKINLVCVDKISSYLLTNYAICENGFSWVSGNEPHAASVFCCIATLFLIQKLYLINENKLAHWLSLRQTTNGGFNGRAEKLTDTCYSWWIFSTLIVLKKYNWINKNALKNYILLCQDIEKGGISDNPDCLPDICHTFFGLAALSLIDNLNESEKKYTLQQMHPVYAIPVHTVKMRNLPYHDIDII
The following text describes a protein:
Function:
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MDERFNKWLLTPVLTLLFVVIMYQYVSPSCSSSCANFGEQPRAGEAGQPAAPGPARRAQAPPEDWERRPQLPPPPRGPPEGPRGPAAPEDEDEEPGEPEDEEEEAEEEEEEPDPEAPENGSLPRFVPRFNFTPKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNAILLQSAKSNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVEINEGARRRIEELNFLDVQLYEYAKDLFQQRYHRTKQLERQRDRQRRRGERRLQRDHRGHRWPKQEGNPEGAVTEDYNSQVVRW
The following text describes a protein:
Function:
Pair-rule protein that determines both the size and polarity of even-numbered as well as odd-numbered parasegments during embryogenesis. DNA-binding transcription factor that acts primarily as a transcriptional repressor but can also function as a transcriptional activator, depending on the stage of development and spatial restrictions (By similarity). May function redundantly with odd and drm in leg joint formation during the larval stages, acting downstream of Notch activation.
Subcellular Localization:
Nucleus.
Sequence:
MEAVKHLSAAAAAAAAAATCSDSPAKAAASPAASSDIAEALGELKASATAAASSASKAATSKHHSNNNHKPSAAATATAAHKKSESCNSNGNKCTAATSPIGSKTSNAAMAAATATAAAATNDLAAAAAVVLSLQGTMVSSLQQAALLPANSAAAAALNLQALESYLALQRLTGKSDVFRFSNSNTGSSNSNNATTCNSSSSEADNNALPSLIDIANIELKSSCSSSSSGEPPLTAATASAAATSSPSSNNSNSTSTPTTSKCVPLPSIGTVSAAVAAAAAAAAAAASQQAALDCATAAELAAECDLPLLDGEDALSFEAGDLDSSYGSFMFNPSAFSQAETDSALHSLQATMYQDKMSVISGAAGGVGAGAVGGLEEAGSSAAAAAAQRSKKQFICKFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKEKPFKCAECGKGFCQSRTLAVHKILHMEESPHKCPVCNRSFNQRSNLKTHLLTHTDIKPYNCASCGKVFRRNCDLRRHSLTHNLSAGVGGVVGGNLSDPFGSGSSSSSELGLPTGSASTAASSRDLVAVSD
The following text describes a protein:
Function:
Required for diploid filamentous growth, haploid invasive growth and flocculation. Putative transcriptional activator of FLO1.
Subcellular Localization:
Nucleus.
Sequence:
MSYKVNSSYPDSIPPTEQPYMASQYKQDLQSNIAMATNSEQQRQQQQQQQQQQQQWINQPTAENSDLKEKMNCKNTLNEYIFDFLTKSSLKNTAAAFAQDAHLDRDKGQNPVDGPKSKENNGNQNTFSKVVDTPQGFLYEWWQIFWDIFNTSSSRGGSEFAQQYYQLVLQEQRQEQIYRSLAVHAARLQHDAERRGEYSNEDIDPMHLAAMMLGNPMAPAVQMRNVNMNPIPIPMVGNPIVNNFSIPPYNNANPTTGATAVAPTAPPSGDFTNVGPTQNRSQNVTGWPVYNYPMQPTTENPVGNPCNNNTTNNTTNNKSPVNQPKSLKTMHSTDKPNNVPTSKSTRSRSATSKAKGKVKAGLVAKRRRKNNTATVSAGSTNACSPNITTPGSTTSEPAMVGSRVNKTPRSDIATNFRNQAIIFGEEDIYSNSKSSPSLDGASPSALASKQPTKVRKNTKKASTSAFPVESTNKLGGNSVVTGKKRSPPNTRVSRRKSTPSVILNADATKDENNMLRTFSNTIAPNIHSAPPTKTANSLPFPGINLGSFNKPAVSSPLSSVTESCFDPESGKIAGKNGPKRAVNSKVSASSPLSIATPRSGDAQKQRSSKVPGNVVIKPPHGFSTTNLNITLKNSKIITSQNNTVSQELPNGGNILEAQVGNDSRSSKGNRNTLSTPEEKKPSSNNQGYDFDALKNSSSLLFPNQAYASNNRTPNENSNVADETSASTNSGDNDNTLIQPSSNVGTTLGPQQTSTNENQNVHSQNLKFGNIGMVEDQGPDYDLNLLDTNENDFNFINWEG
The following text describes a protein:
Function:
Acyl-CoA synthetase required for both the import of long chain fatty acids (LCFAs) (C14-C18) and the activation very long chain fatty acids (VLCFAs) (C20-C26) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. The transport and fatty acyl-CoA synthetase activities are genetically separable and are thus independent activities. Esterifies VLCFAs in the peroxisome matrix. The VLCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Peroxisome membrane.
Sequence:
MGDWEVFGFSALVVSLIVAGVKRNSIVNFIQDFKDVSSLAKALVGIKVAGRKNRTILHSLLEGASRYPDRPFLLYQDEKYTYADAEAESNRIARWVKTNSDLVQEETVAVLMRNEPAFIWVWLGFAKLGVGTSLLNHNLKAESLMHCIRVSNARFLIMSRAFIDIAKELLPELQQLGIKVWVLGSAFNGTVIPDGMVAMETSQMTGNPLPPDQLAPITHSTIASLIFTSGTTGLPKAVKVPHKTPIKAYHAWTLSGGLKPTDVLYVSLPLYHSSGLLNGVLSCLSSGCTVALAPKFSASRFWDDMRKHKATAFLYIGELCRYLLAQPEKPDDGKYPSPVRLAYGNGLGADIWERFQKRFNIERVVEWYTATEASGGFINTDGKVGSVGRYSWLAEKLAGNCVVVECDFATAQPVRGPDGKCKPVPRGETGLMLFKLDNFNKFLGYRGPSQQTQNKLVHDVKKTGDLFFNSGDLMMVDVDGYVYFKDRLGDTFRWKGENVSTTEVSNVMSRLSSIMECNVYGVEVPGCEGRAGMAAIVLHDGDSLDPKHFFDHAINHLPDYACPKFIRVMTEMDITNTFKHKKKQLVSQGFNLEMISDDLYVVDKVKGSYVQINPSIMESIQRQSYKL
The following text describes a protein:
Function:
Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair, and which is essential for nucleotide excision repair (NER) and interstrand cross-link (ICL) repair.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MAGNTGELLEFDRQIFLDLLNEDGLVIMAKGLGVDRMMLNFLKLYCSPKSFVLVLNTSNYQEEYFIEELKAHNVDLIPKIITSQYSSIEREEIYLQGGVLFVTPRILVVDMLSKRVPIHLINGIIVAKAHKMIESYQEAFITRLYRQNNKNGFVKAFSDAPSTFTSGFSQVEKVMKNLFVRKLFLWPRFHATVTGCLEKHKVDVVELLIPMTKHMVTIQTAIIDIIYTCLKELKKGNPSLDTSDLVVENAMSQAFDNIVKVQLEPIWHQLSGKTKQLIDDLKMLRLLILFLTQYDCITFLNYLESVRTNGTRLNKYSLWLFLDSTNVLFTLDTLLEPNPKWSLLTKILEEIKDMDCNSEEKRVLICALDERTCYQIKNYLIHGEREALMRNFNRTRSEKNKISLADGKESRFHLLWLNSQKNRKKNVKVMRQKIRKRLAKRRAKQVCCIAYDPNGFLCKECTNAIHLNPEEIEGLPLNAITIHPLHGCSDPYSLTRVLTSLNPRFVILYDPELVFVRQLEVFKASRPGQQLRVYFTMYSSSAEEQKYLTALRKEKEAFETLIREKAAMVIPEEREGKSDSCQQFSCDIQSIAMNVDTRIAGGRSQVNRNRKIIVDVREFRSELPSLIHKRGIDIVPITLKIGDYILSPDMCVERKSLSDLIGSLNSGRLYNQVVAMTRYYQRPILLIEFVKNKPFVLESKRFHPGEISFQDLTSKVALLTLQFPKLRLLWCDSPHSTAELFEQLKLNHDEPDPNYASEVGDEENAVVQYDMYTPKTQDFVLKLPGISIKNYRSIMNNIKDFQELRTANKERLIELLGNTNVGKNLWEFIHSVNQKVSATSTVSRKK
The following text describes a protein:
Function:
Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cPMP.
Sequence:
MMMMPLRCLSELARRRPDRAVDAMRVGLRCLMSTCPLSKATDDSQRLYATSSCANVPEVALSEAPLSDMLVDSFGRFHNYLRISLTERCNLRCQYCMPAQGVQLTPNSELLSHDEIIRVAGLFVTSGVDKIRLTGGEPTIRKDIEDICLHLSGLKGLKTLAMTTNGLVLSKKLPRLKECGLNALNISLDTLVPAKFEFMTRRKGHSRVMESIDASIQLGFQSVKVNCVVMRGMNDDEICDFVEMTRDKPVNVRFIEFMPFDGNVWNVKKLVPYAEMMDKVRQRFKGVERLQDHPSETAKNFKIDGHAGTISFITSMTEHFCAGCNRLRLLADGNLKVCLFGPSEVSLREPIRAGVDDAGLREIISAAVKRKKAKHAGMFDIAKTANRPMIHIGG
The following text describes a protein:
Function:
Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III (Pol III) which synthesizes small non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs from at least 500 distinct genomic loci. With POLR3H/RPC8 forms a mobile stalk that protrudes from Pol III core and functions primarily in transcription initiation. Pol III plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-kappa-B through the RIG-I pathway.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus.
Sequence:
MKLKNGNAGLLTNFELMDLFKSRGADRGNLGVANTLSPAEMKVYDYLEKTPAGSQTRENIVAFFKATEQYKLTKAEYLQVSNLRPASAVEVHLIVEDCDERLSSDAVDQFLGAIEEILPPIPELEEPAAEGDAGEEDAEADGDEMEA
The following text describes a protein:
Function:
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MMAAQPTANPGVRLGWKAPGALASPPRLALSRSAAAPLASHRVGRGKFSAAAITTDDYLPMRSTEVKNRTSVDGIKSLRLITAVKTPYLPDGRFDLEAYDSLINTQINGGAEGVIVGGTTGEGHLMSWDEHIMLIGHTVNCFGTNIKVIGNTGSNSTREAIHASEQGFAVGMHAALHVNPYYGKTSTAGLISHFDEVLPMGPTIIYNVPSRTGQDIPPAVIEALSTYPNMAGVKECVGHERVKCYTDKGITIWSGNDDECHDSRWKYGATGVISVTSNLVPGLMRSLMFEGENAALNEKLLPLMKWLFSEPNPIGLNTALAQLGVVRPVFRRPYAPLSLEKRTEFVRIVEAIGRENFVGQKEVRVLDDDDFVLISRY
The following text describes a protein:
Function:
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. Binding to F-actin is regulated by tropomyosin. It is the major component of intranuclear and cytoplasmic actin rods. Required for accumulation of actin at the cell division site via depolymerizing actin at the cell ends. In association with myosin II has a role in the assembly of the contractile ring via severing actin filaments. Involved in the maintenance of the contractile ring once formed. In association with profilin and capping protein, has a role in the mitotic reorganization of the actin cytoskeleton (By similarity).
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Note=Throughout the cytoplasm (but not on the cytoplasmic cables) and major component of the cortical actin cytoskeleton.
Sequence:
MSRSGVAVADESLTAFNDLKLGKKYKFVLFGLNADKTSIIVKETSNERDYDVFLEKLPEDDCLYAVYDFEYEISGAEGKRSKIVFFTWSPDTAPIRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESVLEKVSRGAGSH
The following text describes a protein:
Function:
Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B.
Subcellular Localization:
Lysosome.
Sequence:
MGAGPALLLAALLLLLSGDRAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQRILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGEDGYFRIRRGTDECAIESIAVAATPIPKL
The following text describes a protein:
Function:
Plays a critical role in intestinal function. Acts by promoting the development of enteroendocrine cells (EECs) of the gastrointestinal tract and pancreas (By similarity). It is thereby required for normal enteroendocrine peptide hormone secretion (By similarity).
Sequence:
MAAGVIRPLCDFQLPLLRHHPFLPSDPEPPETSEEEEEEEEEEEEEEGEGEGLGGCGRILPSSGRAEATEEAAPEGPGSPETPLQLLRFSELISDDIRRYFGRKDKGQDPDACDVYADSRPPRSTARELYYADLVRLARGGSLEDEDTPEPRVPQGQVCRPGLSGDRAQPLGPLAELFDYGLQQYWGSRAAAGWSLTLERKYGHITPMAQRKLPPSFWKEPTPSPLGLLHPGTPDFSDLLASWSTEACPELPGRGTPALEGARPAEA
The following text describes a protein:
Function:
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (Probable). Required for accumulation of the chloroplast NAD(P)H dehydrogenase (NDH) complex.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Sequence:
MAVSSLSIRCGGFSPTISHKTEILCPNPSLKACCLLSSGGKADSSESTYQKGSGNNWKRRQALVGVGTLVATSIPATLLLAEEIPKSYSPFVDREDGYSYYYPSDWREFDFRAHDSAFKDRYLQLQNVRVRFIPTEKNDIHEVGPMEEVVYDLVKHKFAAPNQVATIYDMKERVEDGKNYYTFEYGLRTPIYATTSFATVAVGNNRYYTLIVGANERRWRKVKKQLQVVADSLKILQI
The following text describes a protein:
Function:
Transcription repressor that binds specific DNA sequence such as the GT-box-like motif 5'-CGTGATT-3' in the AT2S3 promoter. Negative regulator of seed maturation genes during seed germination and seedling development. May target GT-box-containing embryonic genes by competing with the binding of transcriptional activators to this promoter region. Contributes to the maintenance and control of seed filling and may repress the maturation program during early embryogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MEDDDEIQSIPSPGDSSLSPQAPPSPPILPTNDVTVAVVKKPQPGLSSQSPSMNALALVVHTPSVTGGGGSGNRNGRGGGGGSGGGGGGRDDCWSEEATKVLIEAWGDRFSEPGKGTLKQQHWKEVAEIVNKSRQCKYPKTDIQCKNRIDTVKKKYKQEKAKIASGDGPSKWVFFKKLESLIGGTTTFIASSKASEKAPMGGALGNSRSSMFKRQTKGNQIVQQQQEKRGSDSMRWHFRKRSASETESESDPEPEASPEESAESLPPLQPIQPLSFHMPKRLKVDKSGGGGSGVGDVARAILGFTEAYEKAETAKLKLMAELEKERMKFAKEMELQRMQFLKTQLEITQNNQEEEERSRQRGERRIVDDDDDRNGKNNGNVSS
The following text describes a protein:
Function:
Acts as a negative regulator of fluconazole resistance, primarily through down-regulation of the ABC transporter gene CDR1 via inactivation of the PDR1 transcriptional pathway.
Subcellular Localization:
Nucleus.
Sequence:
MKTCYYDLLEVRSDASDLDLKKAYRRKALQYHPDKNPDNVEEATTIFAEIRAAYEVLSDPQERAWYDSHKEQILSDTPLNPNDEDDDYVVDSTVTGVTTEELMMFFNSSLYTSIDNSPAGFYQIAGKVFAKIAKDEVSWGLRLGLDGYKNYKDMEFEEHINSRGYILACDSSKANLSNLLFPIFGYSSTSYEELKLFYTKWSSFNTLKSFTWKDEYMYSRNYDRRTKREINKRNEKARAKAKEEYIKTVKRYVNFIKKLDQRMKEGAKKAAEKRLADERLRKENEMKLRKERLNNEQGAQFHLQSWQTIDQENWKELEKQYEKEFEKRNVDKDDELIGHEFTKNQFQTNNNSQHEDVDEIIIYDCFICKKSFKSEKQLENHIKTKLHKRNLDRVQKEMKKDSMALGLDELSDYNDFDSAESETEKLYSGMDLNDIDAELKKIEEQLAQSSVTDSEDFTDDNNDTEDQNSLVDKLSNTNYDIEIDDEINDDTNEEVQISGADNSETQNAEQDHDSNGDSEEEKEDELTRILRELEESKTSRSNFSDSDEEWSNKKKTKAKKKKNKANTPDKQPVTANKNDAKEVCGECRAEFESRNQLFSHIQTEGHVSPLSKVKKGKRSKKNK
The following text describes a protein:
Function:
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
Subcellular Localization:
Cytoplasm. Mitochondrion inner membrane. Mitochondrion matrix.
Sequence:
KATKPLDKRTAIQALNSLRIHEMPVELKSTSYVTDLMQAYMRRMQITDQDRDDMKIIHVAGTKGKGSTCVFVESILQKHGLKTGLLTSPHLVEVRERIRVNGKPISNEMFFKYFWEVSELLQVYDGNSELRKPNFVQMLTAMAFYAFKHETVDVAVVETSIGGAYDITNVIDTPVCCGVTSLGIDHTEYLGSSLKEIAWHKSGIFKPGAPVFTVPQPEEAMSVLQQRAVDSGSELMVVPEFDLYPGAKKLNLGLAGSHQKYNASLALQLTQCWLQRTSQQYVASALDSHTSQDIFPINQTVQEALRASRWEGRCHVIKFSSVTFYIDGAHTEESLHCATKWFKEETTKEKSALDSPCEKILMFNASTKRNFQKFLQILFPCDFSQSIFVPNVATFSPMENLDQANVSIPIENQIFQVFRNRDAWREICNSKNRPIPNDKSTAFLTVADALSAVEYTPMDFNGKHLQVLVTGSLHLVGSLLLILKNIN