lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLVRAQVRNEYGLGQPELYKEANREDPKAVLDGVAVAGLVGILRQLGDLAEFAAEVFHGLQEQVMSTASRSHKLMIRVQRIEAALPPLEKAVLAQTSHIHFAYTAGSEWHPRIHNEKNHFIYNDLPRFIMDSYEVCRDPPCLHLLDKFDAGGKGSCMKRYSDPTYFKRASGSCIEEDAEKVPRDKKTRKSKKRRSSHRNGELSRVASLSNRSGRMQYTSPIVNGRTSSSQTASTVDMALKSDMGEHSTSFDSRTGSGYINCVLNLGSSMLPEEQEHKEVSSRLMQETDTLSSDFPVGQTQVVDDNFSHSSSQEQIALSSYCVTWDEKAEIVESKAGNWDGDEAPEMNFDVDVQESGPANLGNGDQTDIPFNDTDAPQSSSIDNQNDEIESEPDNYMDALNTIESESENDIECHTKREVELCSENDVECQTKWEVEQIDDANAVNNENREDGMHAVMDSNANHHPSIIESSASSDILSNNGMSMSLSDPVPSENFASEQIPQISGKAPDPDHSPGTDLCMSDEIHNGSQVESAISDPSSSSGSTISDMQDLVSDRIINNVSDSEYSHTEFSGVHSVGFWTNGGLLGLQPSKPPDFAVSTAGQSFAAKSSEAFGPPNQTLMPIHDGPKGNTGTVVENAESAEKVPSSCSEKTSLPIADLAANLEKAVSSQCDNNLDNFNGAGLSLNTSLPHGNKHPVNPNIKATSVESDEENDDNSSRMFGLGHKLLVNGFRRKVSIAHYGESEPATSTKTGVLEPRNGHQSILYQKIPRTTFDEQIGNGSPVNSLTSSPPLEHMKISFNPIDGFETSKLRLQFPDGNHYQESVRDMFPSFQLVPGPVVPVHDVGSDSDDDTFCRSSPYMSDDCLSHCSESNSEQWESGETPESKDPALYDALSRLSSVESVSSSLHFGEAANNGIHVNGGHKSVVPGIGAEPSLPLSLDLPSFDAINPILQDETNSNSVHKNQPELQNSTDVTPLPPPPPPVQWRVSKPCLDETEERQHALSESLRHELDLKLFSAVSVESKPPSDDQQQISDEAIALKPEKKQVDQENLNRQKEANQVSSGRGVDEKEDFLHQIRTKSFNLRPTATAKPTVTSGPTTNVKVTAILQKANAIRQAVGSDDGEDDDNWSDT
The following text describes a protein:
Function:
Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
Sequence:
MAGRKGGRAKRRKVCFFTANGITRIDYKDVDLLKRFVSERGKILPRRVTGTSAKYQRKLTVAIKRARQMALLPYVGE
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MYLIVLLLPFINAFFLGFCGRLIGTIGSGVLSTICMGSSTLIALLLAYEILVNDAVVHIELYKWVESEILITHVGLLYDTLSVTMLLVISSISTLVHIYSTSYMSDDPHVPRFLCYLSLFTFLMMVLVTSDNYLQLFIGWEGVGVCSYLLVAFWTTRIQANKAAIKAIVVNRVGDVGVILGMILIYKTIGSLDFSALEAGFVKPPILDNGARLDPWAPWAPIGILLLIGCIGKSAQLGLHTWLPDAMEGTDSNGSRAPQHKWTAGVFLMIRSFPLFEKAPLALLIITIFGALTAFFAATVGLVQNDLKKVIAYSTCSQLGYMVLIIGIEGSHNVGLFHLFNHAFFKALLFLSAGAVVHSTNYDEQDMRKMGGLIHSIPFTYTMMLIGSFSIMGLPYLTGFYSKDLILELTYSGRNMGVPYFISEQGHHLESLEGSIGSQGGDKRPWGGAEGSGPAPLAPPLIALWPESEPSRGSAFAFWLGTFAAFLTAFYSIRLVYITFIISPNSSKESLISSHINIVDKRVLTVLSLLCFGAIFFGYLFQDILIGDIEHPIVPPFIKVLPTLAGVFGMSLSLLLYWGFDSIGPLFILPIYSFLGGAWQFNHTINKLIAIPFFNFGHWGTYKTLDRGWLELFGPQGAGYLGTRVSQAISNLQSGVISRYALVLLSFTIIFLSLWG
The following text describes a protein:
Function:
Phosphodiesterase (PDE) that catalyzes the hydrolysis of 3'3'-cyclic GMP-AMP (3'3'-cGAMP), leading to linear 5'-pApG. Also displays 5'-nucleotidase activity, further hydrolyzing 5'-pApG to 5'-ApG. Counteracts the function of the 3'3'-cGAMP synthase DncV, and is involved in the modulation of intracellular 3'3'-cGAMP levels. Enhances bacterial chemotaxis and inhibits intestinal colonization in vivo. Thus exerts a crucial role in regulating bacterial infectivity through catalyzing 3'3'-cGAMP degradation. Is specific for 3'3'-cGAMP since it cannot degrade other cGAMP linkage isomers (3'2'-, 2'3'-, and 2'2'-cGAMPs). Is also able to hydrolyze c-di-GMP but not c-di-AMP.
Sequence:
MRWSEIGCTMKSVNIEWNVNLRQAFFCIARALDSVGVDDINHGHRVGYMAYSCAQAMEWSEEECQLVFALGLIHDCGVAQKRDFYRLLENMQPDNTQQHCVRGNELLSNCPPLAPFADAILYHHTPWDELKNIAISDRNKRFAALIFLADRVDYLKELYPRDEYGNVTQEARNQVCLEIGRLSGSLFERDLVRTMQHLLSKEFIWFSMEHHHIEAMGHNLPSTPFFEQKLGVEEIMSIAMLMANVVDAKSQFTFQHSQKVAELCQHLAKELGLNVEMQKALYLTGLVHDIGKLHTPEEILHKPGKLNESEYLCIQRHSTDSRYTLQMVFGQSVVCEWAGNHHERLDGSGYPRGLQGAAIDLPSRIIAIADVFQALTQARPYRGSMSLNEVMNIMRHEVSCGRLDSQVFDVIVRNSQQYYQLSIAESPTEWA
The following text describes a protein:
Function:
Component of the autophagy machinery that is recruited to phosphatidylinositols on preautophagosomal structures, which are early autophagic structures, to promote autophagosome formation, and the subsequent degradation and clearance of engulfed apoptotic cells and P-granules in somatic cells. In particular, binds with high affinity to phosphatidylinositols including phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 5-phosphate (PtdIns(5)P), and more weakly to phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Plays a role in mitophagy, which is the autophagic consumption of mitochondria, in response to dietary restriction. Involved in xenophagy, the autophagy-mediated degradation of pathogens and pathogen products, such as toxins. Also plays a role in membrane-pore repair. In a daf-18/PTEN- and daf-16/FOXO-dependent manner, required for the proliferation of germ stem cell progenitors in the gonad during the late phases of larval development. By regulating the release of neurotransmitters and neuropeptides, involved in the control of lifespan in response to dietary restriction and daf-2 signaling. Probably through its involvement in autophagy, required for dauer formation.
Subcellular Localization:
Cytoplasmic vesicle, phagosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Partially localizes to the phagosome membrane of engulfed apoptotic cells.
Domain:
The L/FRRG motif is required for recruitment to phosphatidylinositols including phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), phosphatidylinositol 5-phosphate (PtdIns(5)P), and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
Sequence:
MSATTSEENPDSINYIGFNQDSKVICVGHKDGYMFYKTADILENNTLTYEGENLTHLGLNNCLIIERLFSSALMVVISQKDPRVLHVYHFTSRNIICDHRFNKSVLTVRLNRDRIVVCLEDCIYIYNLKDMKMMHNIMDTPTNKLGVLDLTSNPGNALIAYPGSTDTGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTVIRVYSVPNGHRLFEFRRGVTRCVNIYSLCFSSDSKYLTSSSNTETVHVFKLEKTEGVDNKPEASTEGGGWFDAINKTFSAYMPSQVLQVGELMTTERSFATAKLPGAARSNQVSLVSHKNQQYVMAATSDGFVYAYRLDPEGGELDLIKQHNIGPKSDTSRASPTSTGSGGAAKSAEASNQSVPNMDDPDDFPPMSHTSG
The following text describes a protein:
Function:
Pectin methylesterase (PME) inhibitor that probably targets root-expressed PME and PME3 in a moderate pH-dependent manner, mainly in slightly acidic conditions (pH 6.3 and 5.0) and to some extent at pH 7.5; this processus relies on changes in the protonation of amino acids involved in intermolecular and intramolecular interactions. Regulates de-methylesterification of pectins in roots and affects root growth.
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MELKNTIFLVILLSITILQSSSATPNRSESDQFIVSSCQTTQYPSLCVHTLSAYATKIRHNNDQDLAQTALIISLARAKSVTIFVAKLTKETPKFKRREYLAIKDCIEVLGNSVDRLAQSVKELARAGHAVASEDFMWKMSNVQTWVSAALTDETTCLDGFSERAMGGKVKRLIRYKVVHVAQVTSNALALVNQFAEKRSVKFP
The following text describes a protein:
Function:
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Subcellular Localization:
Cytoplasm.
Sequence:
MATVAFHTLGCKVNHYETEAIWQLFKEAGYERRDFEQTADVYVINTCTVTNTGDKKSRQVIRRAIRQNPDGVICVTGCYAQTSPAEIMAIPGVDIVVGTQDREKMLGYIDQYREERQPINGVSNIMKARVYEELDVPAFTDRTRASLKIQEGCNNFCTFCIIPWARGLLRSRDPEEVIKQAQQLVDAGYKEIVLTGIHTGGYGEDMKDYNFAKLLSELDTRVEGVKRIRISSIEASQITDEVIEVLDRSDKIVNHLHIPIQSGSNTVLKRMRRKYTMEFFADRLNKLKKALPGLAVTSDVIVGFPGETEEEFMETYNFIKEHKFSELHVFPYSKRTGTPAARMEDQVDENVKNERVHRLIALSDQLAKEYASQYENEVLEIIPEEAFKETEEENMFVGYTDNYMKVVFKGTEDMIGKIVKVKILKAGYPYNEGQFVRVVEDEITEHMRLSS
The following text describes a protein:
Function:
Required for nuclear protein import, its predominant substrate seems to be ribosomal proteins. Binds to nucleoporins and the GTP-bound form of gsp1 (Ran) (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Nucleus envelope.
Sequence:
MDAQFTLELTQLLFQSIAPDTTQITEATRALETKYLKEPGSLLSLFHIMGTCENPQVRQLAAIEARKLCHKYWSSVDADVQNQIRSNLLDITLKEPESIVRHAFGRVIAALAKLDLPEGKWNELSAFLVQATMDQNDSIREMAVYVLYSIAETVDLDNKLLLDFVNLFSQTITDSSRTVRVTSVQGLGAIAEVLESDDKKLLHAYRATLPGMLLVLQDVVQVGDVDASKQVFDVFNTFLIASGAIISKALGNIIEIITGIANSKQVDDEIRCMALSFIISCIRFKSRKLQALKLGKPLVLTLMEVATEETTDDIDEDCPARLALRSIDLLSTHLSPSQVFYPMFEAACAFSQSPQASYRKAALLSIGVAVEGSSESVAGNLPNIFPIIINGLCDNDMDVRQAALLALSQIAVEIPTEVSKHHAQLLPLVFELMSTQGVKVGKSACNCIDALLEGLDKSEISGYLPMLMERLVGLLEFSDTPDIKSCVAAAIGSAAFAAQDDFIPYFERTMASLSQCLHTTDDDEGYELRGTVMDTLGAIANAVGKQAFLPYTEQLIQLAYEGIQIDHSRLRECSFCFYAVLARVYKEEFAPFLEHIVPALFKSIDQDESDILSERIGAPTAEEISQLLDSVETNEEENDEELEKAMGVNSAIAMEKEIAADALGEICMYVGAPFTPYLEPTVEKLVACTTHFYEGVRKSALSSLWRCATTYYKVCNVPQWQPGLPLKVPVPDTVKNIFEAVRKCTFDTLEEEYEKTVATDILRNFAESIKTCGPVVLGDDYEKLCEVVMEVLQKQHIVQAGDVFDDDFEEEDIVSNEEVDDTEQDALLIDSACDVVIALAVALGGSFADSFKVFYPQIVKYYMSKNGNERAMAVACVGEVAGGIESAITPFTRDVFSLFMAALEDSEGEVRSNAAYSMGLLCQFSTEDLSSEYLNILQKLQPFFTQEVFRTALDNAIGCISRLILHNQNAIPVDQVLPIVFSKLPLKEDYLENAPLYHMILALYRQQNPCLVQHLGELIPVFASVLTGSPEQLNDELRSELLSMVKEIAPQYESVVSNYPQLVALLQ
The following text describes a protein:
Function:
Involved in glutamate biosynthesis.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MSAAQGLALKLRAAPAAGGVRGEKRRRAASATAAAAARPRHGAMSLEGGFLGGALPAEDRVAPRASASRQAEAGAGAGAARPPPRSMSKIPESSIGLYDPSMERDSCGVGFIAELSGEYSRKTVDDAIEMLDRMAHRGACGCEKNTGDGAGILVALPHNFFREVTKDAGFELPPPGEYAVGMFFMPTDDKRREKSKLLFREKAELLGHTVLGWRRVPTDNSGLGQSAVDTEPVIEQVFVTKSASSKADFERQMYVLRRFSVMSIREVLGVKNGGTKDFYMCSLSSRTIVYKGQLKPSQLKGYFFADLGDESFTSYMALIHSRFSTNTFPSWDRAQPMRVLGHNGEINTLRGNKNWMKAREGLLKCEGLGLTRDEMLKLLPIVDATSSDSGAIDNVLELLIQSGRSAPEAVMMMIPEAWQNDVNMDPERKALYEFFSALMEPWDGPALISFTDGRYLGATLDRNGLRPGRFYVTYSGRVIMASEVGVVDVPPQDVSRKGRLNPGMMLLVDFENHCVVNDDELKKEYSKVRPYGEWLKRQRIQLTDIIESVNEAERIAPSISGALPITKENKADMGICGILTPLKAFGYTREALEMLMLPMAKDGQEALGSMGNDTPLAVMSNREKLTFEYFKQMFAQVTNPPIDPIREKIVTSMECMIGPEGDLSETTERQCHRLTLKSPLLNTNEMEAIKKMNYRGWRSKVLDITYPKKNGRMGLKQTLDKICAQAREAIHEGYTILVLSDRGFSSERVAVSSLLAVGAVHQHLVSHLERTRIGLLVESAEPREVHHFSTLIGFGADAICPYLAIEAIWRLQIDGRIPPNDGKPYTQEQLIEKYFYASNYGMMKVLAKMGISTLASYKGAQIFEALGLASEVVSKCFEGTPSRVEGATFEMLAQDALRLHEIAFPSRTLPPGSADANALPNPGDYHWRKNGEVHLNDPFSIAKLQEAARINSREAYKEYSRRIYELNKACTLRGMLKFREIPNQISLDEVEPAKEIVKRFCTGAMSYGSISLEAHTSLAEAMNTLGGKSNTGEGGEQPCRMVPLPDGSKNPRISAIKQVASGRFGVSIYYLTNAVEVQIKMAQGAKPGEGGELPGHKVIGDIAVTRNSTAGVGLISPPPHHDIYSIEDLAQLIHDLKNANPGARISVKLVSEAGVGIVASGVVKGHADHVLISGHDGGTGASRWTGIKNAGLPWELGLAETHQTLVANGLRGRAVLQTDGQMKTGRDVAVACLLGAEEFGFSTAPLITLGCIMMRKCHTNTCPAGIATQDPVLRAKFAGKPEHVINYFFMLAEEVREIMAQLGFRTVNEMVGRSDMLEIDPKVLEGNEKLENIDLSRLLKPAAEISPGAVQYCVEKQDHGLDMALDNKLIASSTAALRKGVRVFIETPVRNINRAVGTMLSHEVTKRYHIHGLPSDTIHIKLNGSAGQSFGAFLCPGITLELEGDSNDYVGKGLSGGKIVVYPPRNSRFNPQDNIVIGNVALYGATKGEAYFNGMAAERFCVRNSGAQAVVEGIGDHGCEYMTGGTAVILGKTGRNFAAGMSGGIAYVYDVDGKFSSRCNYELVDLYAVVEEDDITTLRMMIQQHRLHTQSDLARDILLNFDTLLPKFIKVYPRDYKRVLDKLKEEKAAKEAEQKAREVVDKKPVEVIQAPNGISVKTEKVMNEEPSSRPSRVSNAVKYRGFIKYEREGTSYRDPNERVKDWNEVAIELVPGPLLKTQSARCMDCGTPFCHQEGSGAGCPLGNKIPEFNELVHQNRWHEALDRLLETNNFPEFTGRVCPAPCEGSCVLGIIDNPVSIKSIECAIIDKGFEEGWMVPRPPLRRTGKRVAIVGSGPAGLAAADQLNKMGHFVTVFERADRIGGLMMYGVPNMKADKEGIVQRRVELMAKEGVQFIVNAHVGSDPLYSVEKLRSENDAIILACGATKPKDLPIPGRELAGIHFAMEFLHANTKSLLDSNLEDGNYISAQGRKVVVIGGGDTGTDCIGTSIRHGCTNLVNLELLPEPPRKRAPDNPWPQWPRIFRVDYGHQEATSKFGKDPRSYKVLTKRFIGDENGNVKALEVIRVEWGKVNGRFQFKEVEGSEEIIEADLVLLAMGFLGPEATVANKLGLEQDMRSNFKAQFGNFATNVEGVFAAGDCRRGQSLVVWAITEGRQAAAAVDNYLSKDDEGETNGTEDIAVSSEGLVQPVVA
The following text describes a protein:
Function:
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Subcellular Localization:
Nucleus.
Sequence:
MSDTAVDTSSEISTKDLKEKKEVVEETENGRDAPANGNAENEENGEQEADNEVDEEEEEGGEEEDEEEEGDGEEEDGDEDDEAETATGKRAAEDDEDEDVDTKKQKTDEDD
The following text describes a protein:
Function:
High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MAPAMESPTLLCVALLFFAPDGVLAVPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVSSTKWFHNGSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAEVVMEGQPLFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTGKVWQLDYESEPLNITVIKAPREKYWLQFFIPLLVVILFAVDTGLFISTQQQVTFLLKIKRTRKGFRLLNPHPKPNPKNN
The following text describes a protein:
Function:
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
Miscellaneous:
MISCELLANEOUS: The Rut pathway degrades exogenous pyrimidines as the sole nitrogen source at room temperature but not at 37 degrees Celsius, a restriction that is apparently a consequence of an inadequate ability to remove toxic malonic semialdehyde at the higher temperature (RutE/YdfG function).
Sequence:
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPKFAQKAALFNIETFFGWVSDVETFCDALSPTSFAHIA
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MGSKYSDIALDLDISSPLSVLFQPLPGLTLSPSSFRTREEARNTTTQQEQLTIFYNGRVSVSHVTQGQASAILGLATEEDVDTTLRISPIDGNNNNTIVESSSDQSSDSSIPPFLLCQQPHMGFSAAAATGMKHSLQRFLQKRKRLHKNSPYRR
The following text describes a protein:
Function:
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
Subcellular Localization:
Cell outer membrane; Lipid-anchor.
Sequence:
MRLKHFKTFLFITMAIIVIGTGCANKKKKKDEYNKPAIFWYQGILREILFANLETADNYYSSLQSEHINSPLVPEAMLALGQAHMKKKEYVLASFYFDEYIKRFGTKDNVDYLTFLKLQSHYYAFKNHSKDQEFISNSIVSLGEFIEKYPNSRYRPYVEYMQIKFILGQNELNRAIANVYKKRHKPEGVKRYLERIDETLEKETKPKPSHMPWYVLIFDW
The following text describes a protein:
Function:
Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity). Appears to ensure that the proper number of prestalk cells differentiate at the appropriate time in development. May govern prestalk cell differentiation.
Sequence:
MMNGLGRQDIDFNTIWKNIADQVYKILTGSQNVSAMFLYEDVYKLCIAQPQPYCEPLYENIKKFFEQHVDQILLIILDTKSDTISEYLKQWKLFFSGCELCNKVIFRYLNLNWINKKILDKKFGHPPDVYEIQILGLMIWKERLFFKIKDRVLKCVEILIQKDRDGELVQHQFISQFMESLIKLDSVDKDRTLYLIEYEASYLENTRQFYTRESVAFIASSGISSYMKKAETRIDEEEQRSQKYLNSSSHDKMRRLLHSILIEKHKELLQSECINYLKDEKLDEIYNMYKLLSRIEGGLAPVLETVQKYIQHVGIDAIKSIPDRNNPDPKIYVETLLKIYLQFSSIIKKSFNNDVSFITVLDLACHKIFNQNHITRNTTKSPELLAKYCDMLLKKGNKQHEEIELEEKLGQIIVLFKYVDDKDVFQKFYSKMLSRRLINGTSVSDDIEKFMITGLKQACGFEYTSKFQRMFNDITLSAETNEEFKNHLIKNSLSIGKIDFSILVLTSGSWSLHSQTSSFIVPQELTLCISAFQQYYSTQHQGRKLNWLHHLCKAEAKSFFAKKSYDFQVTNFQLGILLIFNTQESVSLEEITKFTNLNENELSRTLQSLIEAKILISKKKDQNSINNNNNNNNNNNNNGEGNNSLVDSANNMQPSSSSSSTQEYTVNSAYSNKRSKVKVSSSLQKETPLQNEETYKGIDEDRKLYLQASIVRIMKARKTMNHVSLIQEVIEHSRLRFQPNIPMIKKCIEQLIEKEYITRAEGESDRYLYAA
The following text describes a protein:
Function:
Plays an olfactory role that is not restricted to pheromone sensitivity.
Subcellular Localization:
Cell membrane.
Sequence:
MLQSGQHPAADTEKATVVYQLASNGNHTNGDIGKVRSPSTGTGVAAPRRSKMLVKEFCNRRCILTSSGLLLVASGTFFILFFPIIFQDILHEELKLRPGSRSYDSWVSPPFPLAMDVYFFNWTNPEDITNHSTKPILEELGPYRFIEHPTKVDIEWHDANATVSYRKKSLYYFDEEGSNGSLDDVISSINIVAVSAAKRSKYWGYLKQKGVSLGLNVYEQKINVVKTAGELLFDGYEDNMVLMGKHMFDADEVPFDRVGWFYTRNNSADLIGHYNVHTGVEDIGMLGKMGEWNYKPRTDFFEGTCGMLNGSAGEFYPPGLSKERPIELFTPDMCRSLPLDFEEEVTIHGLKAYKYSGDRRAIDNGTLYPETACFSAGEIVPSGVLNISSCRFGTPVFVSFPHYYGADPFYLDQVEGLSPSKDKHQFYMSMEPTTSVPLDVAARLQLNIMIEPYENINLFSDVKRVFLPVLWFEQHVLMPSELAGEIGQALTIPSIVRLCGIAMVVFGALMLLWIPLERTFFRRRRVAGTIGTK
The following text describes a protein:
Function:
Structural component of the gap junctions.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MKIETPFYSKNITPTYDSDAIDRLRYFATVIILASCAFFIMAKQYVGQSIQCWMPKQFKDGWEQYAETYCLIENTYYVNMNDTNLPTEVTRENKELRYYQWVPFILFGLALVLYIPRVLWMTLQSVIGINISIVTSHLRKNATEGYASADPDIEKKTKQMQYKKKTANRSADGEFWGSRLTVCLMATKVFATVVILLSMGFMDYFMGMGPLYGWTVTKDLLQGRQWQESGTFPRVTFCDFQVRELGYVNNWSLQCVLMVNMFNEKLFIALWWWYVVLAVLSVYDIFRFIFRFTVHHQVSFISNILSSTGDFDDVSDTEVGEFNRKVLRVDGINLTHLIYANATIFEAADFYAPTWFNNFKVSASKTSKTVSRIARSPIQMVAVVS
The following text describes a protein:
Function:
Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins. Involved in activation of the JAK/STAT pathway. Catalyzes ubiquitination of methylated RBM15. Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA. As part of the PINK1-regulated signaling, upon mitochondria damage, ubiquitinates ABCE1 and thereby recruits autophagy receptors to the mitochondrial outer membrane to initiate mitophagy.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSRSPVLKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPYPEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRLADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVVVDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKLLQELYKLNPNFLQLSTGTVDKNKNKVTALQRYDVPNSNNKDAWPSLQNSNRSANGLEHRKSPPILDNGLDPDHMTPDGPDSDFGLFWESAEHNVAKFGRGIEDDTSSIDKSSESLSIGNGDNLQQILTSDTPSPPPGLSKPNPSAPISSANHSARSPFEDAMTESQSLFSDNFRHPNPIPSGLPPFPSSPQTSSEWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQQEDDLGFDPFDITRKALADLIEKELSVQDQPSLSPTSVQNPNPHLAPKGPSSGFLHPTPASNANSIASTFSVLPQRFPPFHHRAVYNSFSFPGQAARYPWVAFPRNNIMHLNHTANPTSNSNFLDLSHPPQHNTGLGGITVADHSNSIEGLNMKEWQDGLKALLPNININFGGLSNASTPSNATHSAPTSNTATTNSLNWDSSGSWMDPAIISGIPSSTGNGLESLQDDNPPHWLKSLQALTEMDGPSSSLLPHHPHNNLFSAQIPLHRGNWSPYPPPSNPASFHSPPPGFQTAFRPPTKTPTDLLQSSALDRH
The following text describes a protein:
Function:
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MAGGIVAVPLLGFSLLAVALIIERAYFWSQIQLRQNRLVNDVLKLYRSNPPGAIAKLKQNADLPMARIFLEALCLEGATPTEFRLALESATQAELPLLKRFNTLFQTIITVSPLLGLLGTILGLMRSFSSMSLGSTTAANASGVTGGISEALVSTVMGLVVAIATLLFANVFRSLYLRQFALIQEQTGQIELVYRRFHDQPEEKEYATSR
The following text describes a protein:
Function:
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. Also catalyzes the isomerization of glucose-1-phosphate to glucose-6-phosphate, but at a 5-fold lower rate.
Sequence:
MKLFGTSGIRMKNLDPLIAYKVGFAISKNFKKAVIGRDTRTTGNLIESAITAGLLNGGCDVTTIGMVPTPVLGYSAKDYDLGIMITASHNPPEYNGIKLFNKNGTAFDPKQEKELENIINNDDFNECTWDNIGCVVEDKTAVKKYFEYILQNLNLNTNFNVVVDCANAAGCVVSPNIFTEAGCKVISVNSHCDGRFVGRMPEPNETNLKETVDIIKGLNSNGRNYVGIAHDGDADRMIAIDELGRVTDFDKLLAAFCKYLVQKTGADKIVTTVDASMAIEEYLNEFGAKVIRTKIGDVAVAEELEKTGAIFGGEPSGTWIHRDIHLTPDGILSGLRVLEMMEFYGKKLHEIIDEVPSYCNMREKISCPDNLKQNVMDYVSKEGEKIFEKKPETLDGVRFSFENGWILIRPSGTESYVRVRVEAKEKDFAEKLMKTGISMVKTGISGK
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.
Subcellular Localization:
Cytoplasm.
Domain:
The EIIA domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the EIIB domain.
Sequence:
MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNMLSRMMCDALHEADSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMACRETMTSSEFRERIVELGAPEVSSLWHQQQKNPPFVLKHNLYEY
The following text describes a protein:
Function:
May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.
Subcellular Localization:
Cell projection, cilium, flagellum. Note=Localizes to cortex of the fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella.
Sequence:
MVGKSQQTDVIEKKKHMAIPKSSSPKATHRIGNTSGSKGSYSAKAYESIRVSSELQQTWTKRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSVVLEGEAKFEEVSKINSVLKDLSNTNDGQAPTLEIESVFHIELKQRPPEL
The following text describes a protein:
Function:
Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity).
Subcellular Localization:
Cytoplasm. Note=Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis.
Sequence:
MEQERIMQRVQKDVRSLLIASKNGLSIQELEQDYRMMIGSQIPLRSLGYKSTMELLLDMPNVVQIHTQMDGTVNLSAVVDEATRKIADLVSCQKDRSTARSRNRRRNIRPRCPVDLVRRGRVSPVLPATVKSDLRDLLSLSPLLLSELEKAFFSRFGRSFQYTRYGFYSMLEVLRSISDIVEVKQTRTGSLLVLRKSETGHISASLCVKKSLDCQPAAVPNKTSCVFEKCLNEPQRPEKKPSEPATSLKISPPEFQKFSSQEPQSITSSRSFLHSSSNKEPDVNRNVSLGESKKSIENKTSPAVPSNNVVLNNSLVKNSETFESLFTRMSKPVSHVEADHANASEPNSSDLNWLEKKLEKELKLCLARKGAGGSVSDDLRSDIKHVVNQHSNGLNISLLPTAFKSFTGKDLPFKELGFMSVMELVGSLGDILCLESTDEGKDWKLFGAKKEDLVDEFSAGLRSTNSSLSSWNSTRQSTAPLKPVGTIFSKVDEKLWWGPLELKVCSTEQIDIPPDAVRNQKLHCLPRIKHSLMIGVYVESIESPSQFYVRCCGKDTSEKLEDMMIEMRHCYSNECVSERYIVPDNCISVGQIYALRVPGDVWWYRVIVHSIKNSELLDVFYPDFGNVATVKKSWLRFLKNCYMKVPAQAVPSSLPFVTSTEAQWSTQAIKRFRQLCSCLPLVGLVLQYVQDVLVIFLCDTSSAEDVYLHQLLIAQGLAKMEPEHACKKVSRNTFMHYLTPSQEKPQEESSKSSVPSESSQSEVLCTKETILQVIDEVDPEMPYLEAFPTDTDVWDENWVFSDGAGGSNTTPTIPKVETQKQENKISKEQKQPFKFCMDSGDASVVHRPLEEFYISLIKSSKSQESTDIQQSSHTEEQHLAEKSHRCTAEQLQGGSSSSMLCEKKLYYENKDLTYCQQQSKCSFSPLIGFQKLQIPRSATPAALGPAARLATAGRLLYWASDSH
The following text describes a protein:
Function:
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.
Sequence:
MNIISNALFSTRNRCGYCKDREGAEPQGTLFSFNSVQMTAAQYQALIDRGFRRSGTYIYKPDLANSCCSQYTIRLNVEDFKASKSQRGVLNRWTNHVTDKGNGGKNSGKNNQFDLVAKIQEGETDAFNSRLEPNSFTKEKYDLYARYQKHVHNEGPEDISESGFRRFLCSDSFTDSTSDVCKGLDVPDRLSGGYHQLYYHNGKLVAMAVLDILPLCVSSVYFLWDPDYAQWGLGKVAAMREIALAKALGVPYYYMGYYIPDCVKMKYKGEYHPSFVLDPESLTISEQEIDDYPFPEGINVESRALAGVGVWVPLKEMSKNISTMDDSARYYSYVRRSAKTVDRPKEVAARVRYEDLSGAGYLKLEEMMKGLPKFANKKQFVAPQNVLDVIPFEGQKIEYFKYDDDMYSDSEDEEEVEVEEWDKKENEKQTVEGVLVSLASLVDKTNSAFANEMAMGLLAVRATAGSGLGDKTAILMG