lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a single-nucleotide gap, allowing further sealing of the resulting nick by a DNA ligase, points to a putative role in base excision repair (BER) during the B.subtilis life cycle. Moreover, also possesses a 3'-5' exonuclease activity able to edit unpaired 3'-termini in a gapped DNA substrate and likely involved in resecting unannealed 3'-termini during DNA repair. The same PolX molecule could perform the subsequent gap-filling step. Does not display 5'-deoxyribose 5'-phosphate (dRP) lyase activity, as predicted by the lack of the lysine and tyrosine residues responsible for the dRP lyase activity in some other PolX members.
Domain:
The 3'-5' exonuclease activity resides in the C-terminal PHP domain.
Sequence:
MHKKDIIRLLETIAVYMELKGDNPFKVSAFRKAAAALEQDDRSLSEMDDMMSLSGIGKGTYSVIKEYIDEGKSSTLESLQKEVPEGLVPLLKLPGLGGKKIAKLYKELGVHDAESLKEACEQQKVQGLAGFGKKSEEKILQALGEAGKQPERFPIGYALRIAREIEEHLSQFTHIIKFSRAGSLRRARETVKDLDYIIATDHPAEVREQLLELPNIKSVIASGDTKVSVILSFEYETSVDFRLVTEEQFPTTLHHFTGSKDHNIKMRQIAKERGERISEYGVETVETGEIKTFPSEREFYAHFGLPLIPPEIRESGQEVETYSDSIELIELGQIKGDLHMHSTWSDGAFSIREMAEACIKKGYQYMAITDHSQYLKVANGLTAERLKQQAKEIDALNAEFENFRILKGVEMDILPDGTLDYDDDVLAEMDIVIASIHSSFNQPEHVIMKRLETALTNKHVDIIAHPTGRLIGRRAGYEIDIDQLIELARKTNTALELNANPARLDLRTEHLMKANEQGVTLVINTDAHNIEMLDDMKTGVTAARKGWTETKNVLNARSLKDVEAFLKRND
The following text describes a protein:
Function:
Inorganic phosphate and probable anion transporter.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MKLSNIPQRYVIVFLTFLSTCVCYIERVGFSIAYTVAADAAGINQSSKGTILSTFFVGYACSQVPGGWAAQKIGGRKVLLLSFVLWSSTCFLVPLDPNRVGLLVVARLLVGVAQGFIFPSIHTVLAQWVPPHERSRLVSITTSGMYLGAALGMWLLPALVELRGPESVFLAEALAGVIWSLLWIRYATDPPRSEHPKAAAAGFGGALLPTNVNHHKVTHIPWKKIMLSLPVWAIVVNNFTFHYALYVLMNWLPTYFELGLQISLQGMDSSKMVPYLNMFVFSIVGGFIADYLITKRILSVTRTRKFLNTVGFLIASAALMVLPMFRTENGVILCSSVALGFLALGRAGFAVNHMDIAPRYAGIVMGVSNTAGTLAGIIGVDLTGKLLEASKLVYSDLSHPESWRVVFFIPGLLCIFSSVVFLLFSTGERIFD
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MDGNLEVSLDKLPVKRLDSIEENGVERFPPDVGYDETRLSLIRRIDFAWAVEKDDKKKQKKSSKESSTPWQWQSMVENLQLAHQELSVIIDLINTVEANDAVTVAGMTRPKPLPNELLSDLSASAATKLQCFRHLGKYFKQSANALDQQVAREARFYGALIRLQQNWKVKRQRGAASAPGSEGFTIDLFDNSLYDPAAVFRPSSLSTIRVDHDSAGMLSINLPPKSCHSLQFSFLGGHSGESLQEPYKTKTYSSVDYRLRESEKESMSDDECVKETHSLLRETHQAIFDEQVFDLVNREAFNPSLGVNVTGIRENYLQLSIGQGTSVFISLVPSGQGDQTAESLGSQNLENAILPLDSLEGVKLPEEEHDTPKKWGFPNHISYEIYLQQIFHEHILVKAKEKPVFTRSQVSGQGAKDGSSLLGHFCLSLAHRIFSNKVLMELENVVCRVPYLQLISHPTWHSRTSSWTVFMKVPQSILHAGCQARTSNNPRVKNVIKSQFRTKVVVNDDCINIEGEGAPNVLGLFKGNSEEISSMNRYDCDLADLPVTILQQVASQVIGWLHEEALSVGIKANRDFLCLSFELEQGEIVSLVAHVDPEDNQGCISWWLVMEDGFAEERKLHMDGSDGASEYRKFLGHLSLDVLYSTLMDLVSLCSGGGSQ
The following text describes a protein:
Function:
May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MTPSQVAFEIRGTLLPGEVFAICGSCDALGNWNPQNAVALLPENDTGESMLWKATIVLSRGVSVQYRYFKGYFLEPKTIGGPCQVIVHKWETHLQPRSITPLESEIIIDDGQFGIHNGVETLDSGWLTCQTEIRLRLHYSEKPPVSITKKKLKKSRFRVKLTLEGLEEDDDDRVSPTVLHKMSNSLEISLISDNEFKCRHSQPECGYGLQPDRWTEYSIQTMEPDNLELIFDFFEEDLSEHVVQGDALPGHVGTACLLSSTIAESGKSAGILTLPIMSRNSRKTIGKVRVDYIIIKPLPGYTCDMKSSFSKYWKPRIPLDVGHRGAGNSTTTAQLAKVQENTIASLRNAASHGAAFVEFDVHLSKDFVPVVYHDLTCCLTMKKKFDADPVELFEIPVKELTFDQLQLLKLTHVTALKSKDRKESVVQEENSFSENQPFPSLKMVLESLPEDVGFNIEIKWICQQRDGMWDGNLSTYFDMNLFLDIILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSEIYPELMDLRSRTTPIAMSFAQFENLLGINAHTEDLLRNPSYIQEAKAKGLVIFCWGDDTNDPENRRKLKELGVNGLIYDRIYDWMPEQPNIFQVEQLERLKQELPELKSCLCPTVSRFVPSSLCGDPDIHVDANGIDNVENA
The following text describes a protein:
Function:
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Sequence:
MRLLLLASHFTPTYLAPTPDTNSVGGGGARKDEASVKVPSKDPKKKDDKKEDDLSEEDLELKQNLELYVERVQDPNPDLQRAALKSMRQEIRASTSSMTSVPKPLKFLRPHYGTLKAFHQTMPASDLKKCLSDILSVLALTMSAEGQRESLSYRLIGTEGDIGSWGHEYTEEAPIDDLMELVQQIVAFHMKHNAETEAVDLLMDVEDLDLLLEHVDKTNFKRTCNYLTSAAKYLPGPDDMLVLDISYMIYMKFEEYPNALQIALFLDNTQYVKQVFTSCADLLRKKQFCYMIARHGITFELDDEMVADEDDREALQDIVNNTKLSEGYLTLARDIEVMEAKTPEDIYKAHLLDGRASSGASVDSARQNLAATFVKAFVNAGFGQDKLMTVPSDSTTRSSGNWLFKNKEHGKISAAASLGMIQLWDVEGGLAQLDKYFHSNDNPILSGALLGVRIVNCGIKSDCDPALALLGDYVDKEDSSVRIGAIMGLGIAYAAPLDVIAFASLSLGMIYVGSCNEEVAQSIIFALMDRSEAELGDALTRFLPLGLGLLYLGKQESVEATAEVSKTFNEKIKKYCDMTLLSCAYAGTGNVLKVQDLLAQCGEHLEKGDIHQGPAVLGLAMVAMSEELGIDMEIRSLERMLQYGEQNIRRAVPLALGLLCISNPKVTVMDTLSRPSHDTDSEVAMVRIAQGLVHMGKGLLTLTPFHSERFLLSPTALAGIVTLLHACLNMKPIILGKYHYVLYFLVLAMQPRMMLTVDKDLKPLSVPVRVGQAVDVVGQAGRPKTITGFQTHSTPVLLAAGERAELATDKYIPLSPILEGFIILEENADYREE
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MKSVTDGIFNDKIVTCDFRDAFKRGVWAQPQTYGSGVVEALKRQNVTCTLAHLRHVRTPSQYSGKVNDSRYPNKSHTGRFCPVETPEGENCGHLKTLALFAMISSHRDETDVLDNLSGYLQDVDEVPLQQLHVFDKVFLNGRLLGLSTRDEAKAAVLHLRNRRRRGAIHSEVRVLTFPAFHGELQIFTDGGRVLRPVFIVENNEWLLTDDNVSELHGLNNGEEKVRFLLQEGLVELLGPEEEEQCVIASRYSDLRSGIRYTHMELHPAAMLSITASTIPFAQHNLSTRVTYQAQKHSKHAIGYYSCNPSKRFDTTSDSLFYPQKQLVSTSMCRLLSPNDSAMMRGWPEKLMHGQSCVVAVACYDGYNQEDSLIFNQAAIDRGLFRSIHERTHRYNINLQSSEESFGRPVEEDGSPQQRYQHLDEDGFPEIGARLQSSQAVIGKTRKLKEGTVSNSSIFLKNFEEGSVKEVVRLPKIAQGSHDVNVKTASASFPHGGVKVKIASTRAPQAGDKFSSMHGQKGVIGCCLSQEDLPFTRQGIVPDVIINPHAFPTRQTLGQMLESIAGKAAAMGVRVNTTPFSSASPDQLGAALHRCGFQKSGNERFYSGLYGSMIKAEIFVGVCFYQKLMQMADDKIKWRRIGRHDSITRQPIKDRQKYGGIKFSQMERSSLVAHGAAASIQERMFHLSDPHQVEVCTRCDRMASIGRSRAPSCRFCKDKFPGFARLEIPYSCKLLVQELNSMGIDLRLVTDSSASLRGREDKN
The following text describes a protein:
Function:
N-methyltransferase that mediates the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine.
Sequence:
MTKNKSKNKSNNSNISNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNGESQLKNKNKNISENQHIYDKHNHDHSHDHNHDYDDNNEDDEEKEELEHYQLIVSTLLNYSQYSLHWVKDMQDFFHYKLSEDEKKLLPNYNAKMEALARAVLVNSQFLKKIGNEHCNIFSQSSDNSANSERIVDPTNLDHIKIDYFMMDQLKSTIRQLVREWSEEGKLERDQAFEPIKQQLLEIYGHIPFQERSKIRVYSPGAGLGRLCLEIASLGFSSQGIEYSFMMLIVSNFMLNKVEKINEFKIHPYIHQTVNVLRDIDQLRTVTIPDVLSSELLPKNNPALEFSMSAGDFTKNIEENSFDCICTCFFIDTAPNILEYVDCISKILKPGGTWINFGPLLYHHAKKKDSIELSYEQLRYLICKKQFQFKKEEIRDAEYCSNQKSLLRSIYKCQFFVVINNKPT
The following text describes a protein:
Function:
Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
Subcellular Localization:
Periplasm.
Sequence:
MENRESGIGNRLTGHRSVPITNRRAVHILEVSDAPPGFCDSRFPTPDSPKNGTQLARSSASSSGSGPMRLLLLVILLVSAPAWADGYQSVDSIRAAALATVGPDAEAEATLDPGLRMPACPIALQAQPTGTNTVEVACPQPAGWRLFVPLKVRRNQDVLVLRRGITSGETISLADISIEKRDAARIVGAVLADPATAVGKTARRILPAGTLLSANDLVTPRLVRRGDTVPLVSRNGGLEVRMSGRALSDAGENERVSVENSSSRRVVQGIVEASGTVVVSR
The following text describes a protein:
Function:
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
Sequence:
MNEDSALNILPEFSLRQLIQKIATNRIDDDDRSFYIANIGDVIYKVQRWMSLLPRVQPFYAVKCNNDINLLATLNALGVGFDAASKNEMEAIVKICAHSSKVIYANPCKQISHLKFTERHGIALMTFDNVSELHKIKRCYPEAKLLLRIKIDDFGTLYHLSEKYGVDIEDCPNQLQVARDLQLNVVGIGFHIGGGRYDGEIFASAIQLARKAFHYGKSIGYNFDILDIGGGFPGYADAKFETICAKIRQALDEYFPIEDQVKIMSEPGRYFAERAFHLVMDVIGKREINAKELTAQGEQKKYAYYVNESLHGSFGNVLHDFDNQSFLPVSKSLEGLFSSTVWGYSCSGLDYLLKECQLLEALVRISRYSIVLLMALANLLHTILSSYQFGRQLKKNYQNA
The following text describes a protein:
Function:
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.
Sequence:
MRDTMLDERTKKVLYAVVESYIEKPEPVGSRYIMKKYGFDVCSATIRNIMSDLEDAGFLSQPHTSAGRVPTDKAYRFYVDYIFQSELFSQSLEIKRVIENLTKKLRKLRNNMNSLFLETTQSLSQATRYLGLALLPATEKTALHRVDFIKFKDDLVIAVVVNDKGIVKNKIIKVYPEITQKELNSLADFVNRNYHGKTIDEIRDDLIVRIKKEKIFWDRLISKILKMCQEALYFSREDVYVSGFYHIMHLPDFSDIEKLREVAKTIQDRHLLLKLFENISEDDEVKVIIGQENPVEEFRSFSIIASPYKEKDKSLGVIALVGPKRMNYQRAIMLVNAFARSLTRTLSD
The following text describes a protein:
Function:
Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide. Probably involved in the nitrogen metabolism of H.pylori.
Miscellaneous:
MISCELLANEOUS: Asp-168 is probably not involved in the catalytic mechanism, but is probably involved instead in maintenance of the structural integrity of the amidase; MISCELLANEOUS: Expression of the amiF gene is stimulated in a mutant deficient in arginase activity, suggesting that production of this enzyme is regulated to maintain intracellular nitrogen balance in H.pylori.
Sequence:
MGSIGSMGKPIEGFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEEFLLDVPGKETELYAKACKEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQGEIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCICHDGMIPELAREAAYKGCNVYIRISGYSTQVNDQWILTNRSNAWHNLMYTVSVNLAGYDNVFYYFGEGQICNFDGTTLVQGHRNPWEIVTGEIYPKMADNARLSWGLENNIYNLGHRGYVAKPGGEHDAGLTYIKDLAAGKYKLPWEDHMKIKDGSIYGYPTTGGRFGK
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
ASPIDAYTTIKRLSVDWNEIVNQFREPDWLEIERLMMESNDTFPRQTDLVDAGEALIRLQKTYRLNLTDLTRGIIMGHQSMAYLSGADCFYFGQLLYNKADYEHATQWFQEALTKVNFEKQPSVTPRSIHSYLSSSLELRISVNRPLYSTANLLTGLHISAQKRESTFTFNRKFGNRPSHSSANVCTGLYTQTQMSEQAYTFERKCVNHSLHAYVPPDQAPNALCRGEKIRNASEEKDLFCLYDVPHPYFKIGPVKVEQMNKNPYVLQFYDVLWPQEIKAFRRMGDPQLERATVRDTARNTVSHARVSQVAWISPDSDVLLDRVNARVAMLTGLSHRLRKYNSYGPGGHYEPHHDYLEELDEVDKLGGDRIATFMFYLSDVNLGGSTVFPYAKAGVMPKMGSAAFWYNMREDGSYDRATLHGACSVLHGTKHVVNLWFRTNGQTFKRPCPVKRQDS
The following text describes a protein:
Function:
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
Sequence:
MALNNDVNRLGRILGQVLKEQEGEAFFNLVEQTRTLVREVRAGGDPAQLNALLGSLSENDASNLARAFTWYFQLVNIAEEYERVRVLQSRSGVRSQSLAQALADLREQGLSAEDVENLLARVNLELTFTAHPTEMRRRTVRSHLEHIARELPDLGRESAQERVAAHVEALWRTPELRRLKPTVLDEVKGGLNYISTIAQALPKLERDLSDAFQATYGRETAAHVPLRFSSWMGGDRDGNPFVTPEATREALQLHRERARELLLAALRQAYTDLSQEEEEDAAEGTYRTELRALHNAVRDGEPVELLPRLEALNARLHADGQERTAWQLLMPLLSVARVFGQHLVSLDIREHSGQTGAAVAELLKAAGVEADYLGLSEDAKLELLTRELRSHRPLWPAGATFTETLEAVIGPIREVQAAARRVGPLAFGHYVISMSESVSDILEPLILAREVGFRVLPVPLFETLDDLQHAPRIVTDLLALPEYRAVLGDDMQEIMIGYSDSNKDAGFLAANWALHEAQRTISDVCRRAGVRWRFFHGRGTSIGRGGGPASRAILGQPAGTIDAGVRITEQGEALADKYSHPVLARRNLEQALYGVLLAAARPVGDPPADFMAAMTRAAEASATAYRDFVHDPDFLPFFERVTPIHEISRLNIASRPVRRPGAPTLGNLRAIPWVMSWTQNRANLPGWYGLAEGLAEIGPELAAKMYAEWPFFHSMLDNAQMSLAKSDPLVFAEYLTLLEGASTRLADHLRESYARTVAAVESVIGGELMLGEQRLKESIALRNPYIDPIHRLQVELLRRSRSHEGGLDEYERPLLLTLQGIAAGVRNTG
The following text describes a protein:
Function:
There are two distinct cystatins in rice seeds (Oryzacystatin-1 and -2) with different specificities against cysteine proteinases. May be involved in the control of germination by inhibition of endogenous cysteine proteinases. May play a role in defense by inhibiting exogenous proteases such as those present in digestive tracks of insects and nematodes.
Sequence:
MRASSLFAESVFTTSAAAGRRRCPRLAAVPVTLFFSTGRGSPAMAEEAQQPRGVKVGGIHDAPAGRENDLTTVELARFAVAEHNSKANAMLELERVVKVRQQVVGGFMHYLTVEVKEPGGANKLYEAKVWERAWENFKQLQDFKPLDDATA
The following text describes a protein:
Function:
Catalyzes the hydroxylation of narbomycin to give rise to pikromycin, and of 10-deoxymethymycin (YC-17) to give rise to methymycin and neomethymycin during macrolide antibiotic biosynthesis. In addition, produces low amounts of neopicromycin, novapikromycin and novamethymycin. Requires the participation of a ferredoxin and a ferredoxin reductase for the transfer of electrons from NADPH to the monooxygenase.
Sequence:
MRRTQQGTTASPPVLDLGALGQDFAADPYPTYARLRAEGPAHRVRTPEGDEVWLVVGYDRARAVLADPRFSKDWRNSTTPLTEAEAALNHNMLESDPPRHTRLRKLVAREFTMRRVELLRPRVQEIVDGLVDAMLAAPDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVFPDDPAQAQTAMAEMSGYLSRLIDSKRGQDGEDLLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMYALLSHPDQLAALRADMTLLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRRDTAGHLAFGHGIHFCIGAPLARLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRWRRGREAGRRTG
The following text describes a protein:
Function:
Probable methyltransferase.
Sequence:
MNKILIRNFCTNIKNESTKPLIDNIYKNILKDNFKIVEIKDCKNNRGLFYNPIESPTQTLSVINPKTNKPNLIFKEEPFISYPSIIKSNENICNHCLKEIKKEEEEIKQECEECKVYKYCSIECKEKSSIEYHSVLCKSTGSGFNYLEKHASIEKRRFPLLAGKILARMIMGYHLEKSSKSTWLPLQMLSFAKKPPPLEWKDDYLIFSRSLLKGINNESMKKKFDYDWFVRVMQILYLNTIGIDIDPNQQSTKMSSPESGIGLYLLTSFINHDCDPNAFIHFPDDHTMHLSPLKPINPGDEITISYTDTTKDLVDRRSQLFENYGFNCECKKCLNDLLIKRNK
The following text describes a protein:
Function:
Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization.
Subcellular Localization:
Nucleus.
Sequence:
MVMVLSESLSTRGADSIACGTFSRELHTPKKMSQGPTLFSCGIMENDRWRDLDRKCPLQIDQPSTSIWECLPEKDSSLWHREAVTACAVTSLIKDLSISDHNGNPSAPPSKRQCRSLSFSDEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQRYSNGFSTMQRSSSFSLPSRANVLSSPCDQAGLHHRFGGQPCQGVPGSAPCGQAGDTWSPDLHPVGGGRLDLQRSLSCSHEQFSFVEYCPPSANSTPASTPELARRSSGLSRSRSQPCVLNDKKVGVKRRRPEEVQEQRPSLDLAKMAQNCQTFSSLSCLSAGTEDCGPQSPFARHVSNTRAWTALLSASGPGGRTPAGTPVPEPLPPSFDDHLACQEDLSCEESDSCALDEDCGRRAEPAAAWRDRGAPGNSLCSLDGELDIEQIEKN
The following text describes a protein:
Function:
Required for spliceosome assembly where it is needed to link the U4/U6XU5 tri-snRNP to the prespliceosome complexes.
Subcellular Localization:
Nucleus.
Domain:
Interacts with the snRNP via the Nop domain; The coiled coil domain is formed by two non-contiguous helices.
Sequence:
MSLADELLADLDDIEETTESTITDELGPDAKKRRLELQLEEGNGISAELENDLDITKISDSAQKLPSEVANKFNDNNENIYQLLNSTRLRDIIEGTEKYKGTEKQAITGNIEDDLEYHLIVDSNSIAMEIDDEILRLHRLVKEWYHDRFPELSSLVLNAFDYCKTVSSLLNDLDNSKTKLSFLPSATVMVIATTATTTVGKPLPDEMIKNVKNCCEAIQQLGEEKQKIIEYVQSRISVVAPNLSAVVGSTTAANLIGIAGGLTRLGKFPACNLPALGKRRLTTIGINNPAVSGDYGFLYMSEIVQKTPPDVRKQAIRMTAAKVALAARIDSIHEYPDGSFGISARKEVERKIEKLLEPPSQKPTVALPVPDDRPKRRRGGRRIRKMKEQYAVTELRRLQNRVAFGKEEAEVFNFDETEGLGMLGQEGEGKIRAVSIDSRTKLRLPKARKAQLQSMAQKNPLAASGLQSSLSFTPIQGIELVNPLLQRQQKVEEANKWFRDGVFTQIKKDSNEPKNKFS
The following text describes a protein:
Function:
Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'-CCTGCACAGTTCACGGA-3'. Binds to 5'-d(GCC)(n)-3' trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene. Transcriptional repressor of MYC and thymidine kinase promoters.
Subcellular Localization:
Nucleus.
Sequence:
MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTYFKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFLDKLCSQKRDVSSPEENNTQAKNKYCLKINRPIGESTDNQDDEVEEIGDQDDSPSDDTVEGTPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMDTSESKDLGSQTPQGLTFNDGISEVKDEQTPGWTTATSDMKFEYLLYGHREQIACQACGKTFSDEARLRKHEKLHTADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCSSCTKAFAKASDLKRHENNMHSERKQVPTSAIQSETEQLQAAAMAAEAEQQLETIACS
The following text describes a protein:
Function:
Involved in the biosynthesis of the siderophore enterobactin (macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine). Catalyzes the reversible conversion of chorismate to isochorismate.
Sequence:
MNEHIAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHREIENFPELVQATLSNAKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRISERLQLDTTNQLETNENVTFEMTPMPDPEVYMNGVKQGIKKIQVGDLKKIVLSRSLDVKSSEKIDKQKLLRELAEHNKHGYTFAVNLPKDEKENSKTLIGASPELLVSRNGMQVISNPLAGSRPRSEDLVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKDPNTSSLQLAIALHPTPAVCGTPMEKAREAIQHIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKALGLRDSSLNEK
The following text describes a protein:
Function:
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
Subcellular Localization:
Nucleus.
Sequence:
MPSSVTKHTIPPFYACYFLRSLSTPGTTYIGSTPAPPRRKRQHNGHLTQGAYKTSRARPWEMECIVYGFSSKIAALQFEWAWAKPHLSRHLKFLTTEHSVDGTPKNTSDWAGMSLFPSTSLTPGQTRWGRPKKRMARPPSSPNARLLAMRALLRSEPFCGWGLKLAFFTEWSWLAYQRLDACDPGLVAKSALSTLQNRYSRSGKPLHALYPVAVCDFSGVDGKREPLVHVSEPYRLDAGVAEHPVKKRQTSSRQKPHTEETSAWPETLPRSANLKGLDACMQDFATFPIPQPAAPNTDLTKKSKRAKKLSDKARPSALEDHDAENGVDDDDTEVEVVATDAANGSDLALSRPLYRMRFDDLNMEESEWKRFAESIAANVGASRSTTQAMSEFLHTCVQRHIAAQDARTANTALPAPTSLCSLCSIPIDLSQQLDFVLCPNPHASTLPLISSSSTASHETISECRETGCDSIFHLSCLARSFLEQQLGDQKATASSASTVLPTHGTCPCHRGEHKEPTMWADVVRAMYRRHERFERLIQFLIRSGRSLEQHLHPPLEVEMTVKGSKIKERVKASVKATEDAQVDIGDQRQVISGTTSRTKAALTRKRRQPTTSSVNAIQVDPLARNGSKIDGDGAGKDTKKNTTQKAKSNETSEVIDLT
The following text describes a protein:
Function:
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
Sequence:
MHEYSIACEIFEQVIETAKVHGALEVRHVTLEMGRLSHTNPEQLSFCFKAIAEGSIAENAEFIVETIPPSLECECGYTGTVDETQIGKNDELQSELLEYIAALECPVCGKNARIIGGRELIVKSIEIETEVEQ
The following text describes a protein:
Function:
The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
Sequence:
MEDFYVEDYLVKGDRYYTKEHEWVRVKNGFAEVGITDYAQKQLGDIVYVDLPEKGKEVDAGDTLANIESVKNVAPVYAPVTGTVVEVNEDLKDEPGIINDDPYEAGWIAVIEMKDPTEVEDLMTAQDYAEYLKEIVEEEKEEEVEVKEEELIETESIEELSEEELGYEENK
The following text describes a protein:
Function:
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
Sequence:
MLFLKDKRTTLDVAEHTVIIPSICVGNAAQLACDLLIASKELRRIGSITHPALIPVYGPSAYQHEPKEKVSSCELYEGTEDKLLVVQFRAPWVARHTAHFQKELVELLKGARRVVILSGSFGFEKRVIEESPWAYRASENFKEAHAAQLGNEELIKWKEHKGDAIYGGGNALQLFKAFDEQKVPVMLLFRYLLEGDNSTDASLIVRELNELCEDFLQLRNGGDGSFKLTVPKSWNLLFGNDVTELLF
The following text describes a protein:
Function:
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.
Sequence:
MKRERRQELKSPLHICPEVAKSGKVSACPYNDKCRFSHDVEAFKAERPADIEGSCPFLIYEGPCPYGLACRFAGTHRDDVSAPTENLPVKSSELNFFNKDTQKLLWKNKMKFPETESTLKLLGLKGNPKDKTLGGKGENGQVVPKEPATDTKTDNNEVANDSIIPFISPEDDADENNLADDTRPLKKAKSSVNEICSSQVSSGSSVQEGILDSSCDVNKLEPAADTVTDSDKSLKLHPREKKLIDFRDKLYLAPLTTVGNLPFRRVCKVLGADVTCGEMAMCTNLLQGQASEWALLRRHSSENLFGVQICGAYPDTVTKTVELIEQECSVDFIDINMGCPIDIVVNKGAGSALLTKPMRMKSVVEAASLTVGTPVTIKVRTAYFEGKNRIDSLIADMGNWGATAVTIHGRSRQQRYSKLADWDYIYQCVCKAPKSLQVLGNGDVFSYVDWNKHKTECPELSTCMIARGALVKPWIFTEIKEQRHWDITSGERLDILKDYARFGLEHWGSDSKGVETTRHFLLEWLSYTCRYVPVGLLDVIPQRINWRPPSYYGRDDLETLMASDSAADWVRISEMLLGKVPSGFSFAPKHKSNAYDRAENG
The following text describes a protein:
Function:
Acts as a protein phosphatase.
Subcellular Localization:
Cell membrane.
Sequence:
MGSCLSSSGGGGSRRSLHGSPHVPGPGRRKRPPKRRPGSCSSSFDNTEEPLLHRIPGRMFLNGSTDTVSLFSQQGKKGPNQDAMIVWENFGSMEDTVFCGVFDGHGPYGHIVAKRVRDLLPLKLGSHLESYVSPEEVLKEISLNTDDRKISEDLVHISANGESRVYNKDYVKDQDMIQMLIGSIVKAYRFMDKELKMQVDVDCFCSGTTAVTMVKQGQHLVIGNIGDSRAVLGVRNKDNKLVPFQLTEDLKPDVPAEAERIKRCRGRIFALRDEPGVARLWLPNHNSPGLAMARAFGDFCLKDFGLISVPDVSYRRLTEKDEFVVLATDGIWDALTNEEVVKIVAKAPTRSSAGRALVEAAVRNWRWKFPTSKVDDCAVVCLFLDSEPNRLSTASFSKEKHINNGVTEPEPDTASSSTPDSGTGSPELNGVNRIDTLVNLPVYVPTKE
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MVSSAMAAVAVAFAVVVAATMSSAQLDPHFYDGLCPAALPTIKRIVEEAVAAEPRMGASLLRLHFHDCFVNGCDGSILLDDTPFFTGEKNAAPNMNSVRGFDVIDRIKDAVNAACRRNGRADGEPGGGEQQHPGADAQPRRPRLQLRRAGPLRAGPRPPLRRPHAGLLPLHQLPRPPLQRDGHARRLPRRVARGDLPAYRRRRRRQPRAARPDAGEVRRRVLRLAAARQGAPALGPAAVRRRRPRRQPGRVPARLRRVHGEDGQPEPARREPRRGPRQLQEGELLLARTRDGLN
The following text describes a protein:
Function:
Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) to the melanosome in exchange for 4 cytoplasmic Na(+). Involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium-calcium exchanger in melanocytes.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Melanosome.
Sequence:
MDESDYWGLARSNGMNCTQPAIDDFPRDLFTEEQRQNGAVVLHAIASLYLFVALAVVCDKYFVPAVEKICQALNMSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMVVPLDWWPLTRDCLAYGITVAILICIIHDERVEWYEALILVLLYIVYIAVMYYDKSFQKCARGGLKHARKRRSHDTSSSLKSDSSRTQEAIEARTPLRIGHFQQNGNLKNVAHIDAPAELTSPAGGVDVEMQIKPFTSIDLRAPPGGTATATTDLETHKPSAGPSSVDPAPTEGEVGDVPERPPPPPSPATPPVQEQDAGVNGVKETVAGTLPPKEWNGENGHGTTGPVAEAVVRALESGSTGAEVDGNVEGGANGNDGESAPEKDDEDEFKLLKYPLGKSAFTQFSWIITWPIHLLFMFTIPNCETPRFRNWFPLTFIMCIVWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKQGHGSMGISNSIGSNTFDILLCLGLPWFIKAAFSPIEPGHHWVGINSAGLEYSAISLLSTLLMLYIAFSLNKFKLDRRVGNACLIMYAVFLILASLIELNVFFRVNLPTCGR
The following text describes a protein:
Function:
Catalyzes the addition of a phosphorylinositol group onto mannosyl phosphorylinositol ceramide (MIPC) to form mannosyl diphosphorylinositol ceramide (M(IP)2C), the major sphingolipid in membranes of S.cerevisiae.
Miscellaneous:
MISCELLANEOUS: Present with 606 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MNVIFSLASFVKNMYNASLNQRNLISLPFNFMLNFAPVFIWLSIFKRAGLIPIRLRPDIHSKFAFFADQFLFGDYWHELTVQLPDNTSKLFFWSFISSSAFLLVFLICIPFAIWYYIYYIKHVNYNLLEWFANIFHYPCKRKQRPIQKRFRTIFIPFALPLFTFVILNIDHFFAYQSDANFTKTKDLLAWFSYVILHLTAPILTAVYLYVFQPPGTLKCFSFALGLQNIAGVLTHLLVPMASPWFTHLYGIDDTEHVNYTQEGFAAGLIRVDSHLGTHLNTKGFHMSPIVFGAVPSLHSAIAFQCFLFLVSRSTSLKHRFSNAGGFTMHNNDSSTFKLSEEDSEDEGDNSIPPTIGPNDLEMEPLGTVEPVDISNERSSSPSSSFTVSSNERSTGGGDGSIINSNGNKKPLQFVHLYDEDTNFTNKWIFKIVNDGFIPKFWAILYIILQWWATMYLDHHYRFDLFVGVLYAMTSFIIINWFVLQPKVLKKWIHIRLGDKVDTRNEARTFGMRVFCGTKMEWFFDPLA
The following text describes a protein:
Function:
Efflux transporter. Confers resistance to a variety of toxic compounds.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MVDQVNLATEQTSLLYPEVSRKKEELSVNKWTILPALWVGGFLSALDMTIVASLYPVIGSEFKLMNNASYIVTAYLITNTAFQPLYGRLSDIFGRRPTVVFANAAFTLGTFWCGISRSLPELCMARALAGIGGGGLGTMSSIISSDIVSLRERGTWQGITNIVWGIGGSLGGPLGGLIAQRWGWRTAFHFQVPMGILSTILVAWRVRVKPTVRNSNASLLSRIDYLGSFLLVTGITALVVTFNMGGDAFPWVSPVIITLLVSSVLILFAFYWVEKNIAVEPIAPVEILSQPTPLNVCLGNFFNAFCSFVIVYELPLFFETTLLMPSSEAGVRIFPYVISTSVGSLCSGLYMKKTGRYRNLVIAGFFFMLMGIVSFAVLTSFGHRTPLILISLCLAMTGCSYGMNLTSTLIAIISSLAPEEQAVATGLSYLFRATGSVIGISLSQTTTLSILMKQLASNLKDDPDKDDLIRRLRESISIIPNLPKDIQKLVIKSYATAFTWTFALVAIIAFAGFWCSLRIKQFYLHTSVDRS
The following text describes a protein:
Function:
Required for processing of the 20S pre-rRNA at site D to generate mature 18S rRNA.
Miscellaneous:
MISCELLANEOUS: Present with 125 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKIEELPPSDTDDHSYSSKPGDVFLAFVDAPVKETDDILVEDSFIGGEPKWLHPDSEPPAELLKCGACKSADNMKLLLQAFSPLDDEQMSAIQQRLGINNMSYINPQDDRVLYVFLCTECQRKGNSVRCIRGVKKNKNVDSLSEKMASTSLEKDFQINPFDLSNNSDSKCNAFSSNPFGGANANPFGADSINSNISQSKDEGKKKESATVSAKTARKLHDLQKDKEYDGNKCFKSCLLYVEEETFKNKKPAHLQLPKNLKIDKEALDLTGDEDLEKDPIKLDPRTEKLSKFLDDDTFQKFQEVVGYNPLQVLRYDLGGKPLLYAETKVDILSTVPRPGYNPSSQRIFEMQLMPKMIFDLEEVVSVDNGMEWGTILVFTDVENYMPEFDEHGVGYVEECVKVQWESRT