lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
Subcellular Localization:
Cytoplasm. Nucleus, nuclear pore complex.
Sequence:
MSSKHDLNIEDLLSGFDSMKLSALRNAAKLSPLIKERTIGPDCADLSRREVSITILPAAVDSNDTTKENDPNASNEGPSSIHGTPKSEEKKKNAPVTPQFTAIKHSDPTDCTAVQSKLHQQELERQRLASVQKALAERHNKIRLADEQREAQLAKSLHEASLNVARKVQDSEQRLLHAVREQEKLAQAAAAQRQAQMEEENKRLNDIQAQLKRRQEEMRRKAQLIETVRQSIGQFRVGTETFTKALTVIGVQHATKFTNQKKAIRTLQKDFEQLLQGINANQEVSQVEVDQAADYCRQLDQVNVEVTEILAQIEASQKQQQEQLQQQQLQQQQQQQQQQQQEQEQAKVAEAPAPAAQQADSKPTDSTDGSSAAAPADPTAQAVDNEPFFQPVSPECLQFYNEIKSFYEQHQTAVKQLMDDPSMKTYRFNCQKAINVPVNAISAVNREHFIDKYSKLAALLSGQNVKAGDGMVSINGHPLGRTYCTMLLAKKFVSQADTSISSNASAAFPVAAIAVALWQRFPDFGRFFLAYLHRECPYLVPYYLPQHEGQSQEEFLKTLGYRFADGGVLEKQDQYLKRMSGLARLYAAVIVTVPRKDDPTPHPHGLEYGWRWLTNILNRFPQPDICATLIAEFLQTAGSELHAAYGKQFLKVLRVLQGDYMSALNRIDTGGPKARLEGLIAKILTEGRIERPEGIMSVNFW
The following text describes a protein:
Function:
Induces a stably inheritable state of calnexin independence called the Cin state when overexpressed.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSEEIITESIVKNFGSAETSVGEKQPKRKRSEVRAEKLKARKLQKAAEIVQKQKENRKILKDVSLKRLSKSLDRSLPSENTIDQISFNHAMSEEDASGYQIGDKHKNLLLYKLSSSSGSVFTENLYSTIQEFLSAQKVDIADSKNTYVFGSTFDKKSHALVKTSDSVRSLKYGSFVKACAPLFRFASGIIKAHAPHFHQALLKLELAPSALRFGVFPNFSLQSVSNGYMSMESNFSSIKYGFVVIIIVGELNDVELKIPAISHSLKLKDGSILVLRSSLLHQWYSLPKQSILYEIRLFAMSSLWHYEKNKSIKIAKKDDI
The following text describes a protein:
Function:
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MASKPIPLHVAQPTLLTNLNITTLESDKYVCVRQVNSEANAPAETVIIDLKNTNNIIRRPIRADSAIMHLTEPIIALKAQGRTLQLFNLETKERLQTYSHQEDIQFWRWVSQTTLALVSTKAVYHWDVLDSKNSAAPRKIFDRGEQLENNQIINYVTNDDESWSCLVGITSNPAGGIRGNMQLFSKARNVSQPLEGHAATFGTIRLDGAATYTKLFAFAVKSTSGEAKINIVVECDHNASNPAFPKRLIPIHWPAEGTGDFPLGIHIAHKYGILIVITKFGFIHLHDLETGTALFLNRISEETVFTTARDDDGTGVVVINKRGQVLHTTIREDALIPYIMENPACAEIAYKLASKGGLPGADQLYSQRFENLMTQGNFAEAAKVAANSPRGFLRTMNTINRLRQVPSQPGQITTLLQYFGQLLDKGGLNREETLELARPVFVQGRKHLIEKWQKEGKLFCSEELGDLAKPHDLNLALAIYKDKVVAALAELGHYDLILQYCNGVGYTPDYNVLLQHVVRSNGEKGTEFASQLVKNEGGPLISIDRVVDIFQSQGMIQQATAFLLDVLSNDLPEEGHMQTKLLEMNLLNAPQVADAILGNEMFHHYDKARIASLCENAGLLTRALEHNEDPAAVKRIIVQTDKLPEEWLINYFGQLTVELSLDCLDAMLTTNIRQNLQAVIRIAQKYSDLLGATKIIDLLEKHRTAEGLYFFLGSIVNVAEDKDVTFKYIEAATTMGQLNEVERVCRESNAYDPEKVKNFLKEANLTEQLPLIIVCDRFNFIHDLVLYLYKKQQFKSIEVYVQRVNPARTPAVIGGLLDVDCDESIIKGLLASVTPSSIPIDELVSEVESRNRLKLLLPFLEQTLASGNQQQAVYNALAKIYIDSNNNPEKFLKENDQLKLVTLLERADSEIWDYVLSPNNMHRRSLVDQVTSTAVPSSTDPDKVSVAVKAFITGDMPAELIDLLEKIILEPSSFSDNPSLQNLLMLTAAKSDRGRMMDYIHQLEHYTPEDIAQQCIEVGMYEEAFEIYKKHGQHFDAANVLIEHVVSIDRAQEYAERVETPEVWSRVAKAQLDGLRVTDSIESYIRAGDPSNFLEVIEIATHAGKDEDLIKFLRMARKTLREVPVDTALAFCFARTNQLPELDEFLRGTNVADVEASGDKAYEEGYHEAAKIFYTSISNWAKLATTLVHLDDYQAAVECARKANSVKVWRQVNQHCIDKKEFRLAQICGLNLIVHAEELAELVKQYERNGYFDELISLLEAGLAIQACEAAHLWPELIFLYVHYDEWDNAALAMMERAADAWEHQAFKDTIVKATNVEIYYRALGFYLEEQPTLLTDLLQALTPRIDVNRVVRMFVKSDNIPLIKPFLLNVQSQNKREVNNALNDLLIEEEDYKTLRDSVNNYDNYDPVDLAQRLEKHDLVFFRQIAADIYRKNKRWEKSIALSKQDKLFKDAIETSAMSTKSEIVEDLLRYFVDIGSRECYVGMLYACYDLIRPDVILEMSWRHGLHDFTMPYMINLLSQQTAALTGLQKDNEERKAREASQQKKEEDTPILGSRLMLTQGPIASAPSPGPYGQANGIAPQPTGYRGF
The following text describes a protein:
Function:
Transports the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited. Is probably involved in the import of pseudopaline-metal complexes.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MTATAVVLRNAPSSLDFPRASRLSRSVRAALLSLAMAAGAAPLCASAAEAAAEQARPYAIPAGQLGDVLNRFAREAGITLSATPAQTGGYSSQGLRGSFTVQQGLARLLADTPLEAEDQGDGSFVLREAPAKDGDVLNMQAVEVFALGNNLGSTDGYLATHSQIATKTSKPLLETSQTVSVITREQIDDTASKTVQQAMRYTPGIFTGQVGASNRYDYVVMRGFADNSVDNIYLDGLKAMGDSGTFSSMQVDPYFLERIDVLKGPSSVLYGRSLPGGLVALTSKKPLYEDYRQITGSIGNMGQKEMGFDFSGPLDEEKRIAYRLIGLGKGSDTQFDHVKEERYAIAPTLAIDFSDDTTLTLQGYLQHDPNGGYHGGVPADGTLSHHNGRHISREFFDGEPSKDDFDRTQRMFGYQLEHRIDDVWSARQNFRYLDSDVDLSQVYAYGWSASEPNKLNRYFSGAREHLQAYIVDNMLQAEFATGAARHTLLTGLDYQRRRTVVDWRSGSASALDAFNPVYGDDAISYFPDDNHTRRLEQTGVYLQDLIDIDQWRFSLGLRQDWVSVTDKNRSTGSKADDDWEKFTGRIGALYLFDNGLAPYVSYSESFNPNAYSDASGTPLAPTEGKQWELGLKFQAPGSNSFYTASLFHITQENVASKEPQDNFYTSVGEVRSQGLELEAHTQLSDNLKLLGSYTYTDITYTKSLDGNQGHTPNQAPKHMASLWADYAFDAGPLSGLSIGGGARYVGETWADKENTLRVPDYTLVDARIGYDLGKLGLKGLDVSLNANNLLDKDYVASCYSLDFCYFGEKRNVTATVNYQF
The following text describes a protein:
Function:
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.
Subcellular Localization:
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Sequence:
MSALPPVYSFPPLYTRQPNSLTRRQQISTWIDIISQYCKTKKIWYMSVDGTVINDNELDSGSTDNDDSKKISKNLFNNEDIQRSVSQVFIDEIWSQMTKEGKCLPIDQSGRRSSNTTTTRYFILWKSLDSWASLILQWFEDSGKLNQVITLYELSEGDETVNWEFHRMPESLLYYCLKPLCDRNRATMLKDENDKVIAIKVV
The following text describes a protein:
Function:
Involved in the incorporation of a chlorinated tryptophan residue into halogenated forms of the secondary metabolites called chondramides.
Miscellaneous:
MISCELLANEOUS: Chondramides are secondary metabolites with antifungal and cytotoxic activity. They are non-ribosomally produced depsipeptides consisting of a polyketide chain and 3 amino acids (alanine, N-methyltryptophan and beta-tyrosine or alpha-methoxy-beta-tyrosine).
Sequence:
MQLPSSTKILVVGGGPAGSTAATLLAREGFEVTLVEKAIFPRYHIGESLLISVQPIIDLLGAREAVEAHGFQRKKGVLWEWGGERWLFDWKKLRYDYTFHVKREEFDEILLRNAQKNGVKVFEGIDISRLEFDGERPVAAKWSKSSTGESGTIQFEFLLDASGRAGLMATQYLRSRMFMKAFQNVATWGYWKGATIPEVEVEGPITVGSIPYGWIWGIPLRDQTMSVGLVIHQELFKEKRATQSVEEIYHEGLKASPLFQDVVLKGATLEPQIRTETDYSYISRTLAGPGFFLVGDSGAFIDPLLSSGVHLAMHSALLAAASVKSIIAGEVDMASATEFYQRCYQGHFLRWALIVASFYEVNARKETYFWTAQQLAHEELGVFNMSQADMKDVFATMVSGVVDLGDAQNAGRLQKGAERVHQYLDDDGREEDVTALLQKSKQRIFEYLDRVKNRDSRAAMQRYKAGGTETFSMGLDADGAVGGLYVTTEPRLGLLRKVVEERAEAATEAPAPAAPPPAVAEV
The following text describes a protein:
Function:
Component of the transcription coactivator SAGA complex. SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription. At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B. SAGA interacts with DNA via upstream activating sequences (UASs). During SAGA-mediated transcriptional inhibition, spt3 and spt8 prevent binding of TBP to the TATA box (By similarity). As part of the HAT module, involved in positive regulation of matings.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEAEESESFSYPMLLPSDGLYPEDDDDADMDQDKNPEENVMNEKEDEDVDAVDEKSGEEDVEMDTMEDENENDEDTEQTSEKKETEETPKENPLEKLKQKASTASFYDVVPTLAIPMATSINAFAFTSDLKWLFTGGEDGYIRKYDFFPSINGDLSLTVAQRHPFVDTVTKAGILLNYWENAYDGNKPSSVYSLAAHSRGLWVLSGVNNGDIILYSTRHQEGYPVTSLKKHTAPVSCLALHGSEKKVLSGSWDKMVYYWDLNTGDAISTYNCESGQISNIVYRPSGAVNPWGSESDDMRSLFGTPASSSSYDALFDEEVEKAIEEETKSVQANEENETEKPSQTESTTNNDNIKAPSESSSEESNIFLTTSIDGVMNVWDHRMVDSVLKYPVPKGVPPWAMSACWSPDGNNIYIGRRNGIVEEYNIHSGKEPVRSLKMPLDSGPVSNVYSMPNGRHLVISSFDNIRLYDLQSKAGIGFLIIPGHHGGLVSSLYVDTSCQFMFSASGNRGWQGTTTEVFLGYQIMTS
The following text describes a protein:
Function:
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MQLGSGAGMSSAASSTPASWRRTPWTEQTPSTPFLEEMSSMPDDVFESPPLSASYFRGVPSSASPVSPDGVQIPLKEYSSRAPGPGTQRGKRIASKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHILITLLVICTYGIAPVGFAQHVTTQLVLKNRGVYESVKYIQQENFWIGPSSIDLIHLGAKFSPCIRKDRQIEQLIRRERNIERTSGCCVQNDRSGCIQTLKKDCSETLATFVKWQNDTEPSDKSDLSQKQPSAVVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQAQSNRTGLLHIDCKIKGRPCCIGTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDEVCGLLPFLNPEIPDQFYRIWLSLFLHAGIVHCLVSVVFQMTILRDLEKLAGWHRISIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWQLLERPWKAFFNLSAIVLFLFICGLLPWIDNIAHIFGFLSGMLLAFAFLPYITFGTSDRYRKQALILVSLLVFAGLFASLVLWLYIYPINWPWIEYLTCFPFTSRFCEKYELDQVLH
The following text describes a protein:
Function:
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
Sequence:
MAKRTPSIDTKNLTAVQLMELDACVRCGECVKWCPTYAASGGKPGLAPRDKILRWRQYMNKSYGLKAKLFGPQEVSPSELEEFKDDVHGCTTCGVCATVCEAGINTVEIWEAIRTNLVKKGIGPYGKQSAFPKLVGQYHNPYMKDQKDRLAWVPPDVKIEDKADIVYFTGCTAGYNQLALAFATSRVLNKLGIKFAMLGEEEWCCGSALIRTGQVHVDDVARELARHNVEALQKKGAKKVLFACAGCFRAAKIDWPRLLGKELPFEVIHITQFLADLIQADKIKWEKPINKTITYHDPCHLGRHVGVFNAPRYVLSHIPGVKFVEMDRSKEFQRCCGAGGGVKAGMPDLAVAMGESRVKDALETNADILSSACPFCKRNLSDGRDALKSDIVVEDIIELVAEALGLSTS
The following text describes a protein:
Function:
Minus-end microtubule-dependent motor protein. Involved in apically targeted transport. Required for zonula adherens maintenance.
Subcellular Localization:
Cell junction, adherens junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic vesicle membrane; Peripheral membrane protein.
Sequence:
QIMDSIKEAADVNVELLHRYQKEMRLRKKYHNELVELKGNIRVMCRIRPAIDQDGPEPENIISFDKTDDSIINVAYRGSKKIFELDHIFKPNATQVEVFHEVGNLITSCVDGFNVCIFAYGQTGSGKTYTMEGPPDDHGIYQRSLLKIFHEIEERKPHWNYQVFVSLTQIYNESLHDLLGKDPMAKLDIKQKKDGSGLYVPNLNIVEVKCVKDVNNILEEGGRNRTTAATQANVVSSRSHALLCVEVIGTNANNTATSQGKLNLIDLAGSERVSKSGADGERLKEAQYINKSLSALGDVIHALRNKIAHIPFRNSKLTYLLKDSLSGNSKTLMMVQASPAEKNASETMCSLSFAQRLRTIALGAAQKKTESIVDVSIKQNKNAYYR
The following text describes a protein:
Function:
Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
Subcellular Localization:
Cytoplasm.
Sequence:
MSLEFHYSVKDLKESDPSWIGANWGKNQKKSKFDEILTSKWDKAVENGIFKYKLDDCKYKTLTSSKSNPMHCVAQLNPQRSFKRRKRETFSSMNENFTQNQFNFTKICDDEILFTMVPPNDSAATELQKTASRNVVVVNISPIDYGHVLLIPALDECQSQRLTAASLLLAFDFLQLSSNPGFRVGFNSLHAWASINHLHFHGMYLQHQLFLDNIPTSDHVAGSCYLIDGSSPMPAFVFNVPKQKEARVVVATDIEKLVNILHEGETPYNMMLTRGSVGTRCVIVPRKSTQNLEPSDSFDVACVEIGGQYPMKYEKEFCSVTHDSAFKILAKNAVSNKVFDDLVQKIKQIL
The following text describes a protein:
Function:
Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC19.
Sequence:
MRTQVTLGKEELELLDRAAKASGASRSELIRRAIHRAYGTGSKQERLAALDHSRGSWRGRDFTGTEYVDAIRGDLNERLARLGLA
The following text describes a protein:
Function:
Copper-transporting P-type ATPase necessary for the proper uptake of iron. Required for export of copper from cytosol into extracytosolic compartment. Retrieves copper from the metallochaperone ATX1 and incorporates it into trans-Golgi vesicles where they are acquired by the cell-surface iron transporter FET3. Required the production of inositolphosphorylceramide D, probably by delivering copper to a yet to be identified enzyme.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Sequence:
MREVILAVHGMTCSACTNTINTQLRALKGVTKCDISLVTNECQVTYDNEVTADSIKEIIEDCGFDCEILRDSEITAISTKEGLLSVQGMTCGSCVSTVTKQVEGIEGVESVVVSLVTEECHVIYEPSKTTLETAREMIEDCGFDSNIIMDGNGNADMTEKTVILKVTKAFEDESPLILSSVSERFQFLLDLGVKSIEISDDMHTLTIKYCCNELGIRDLLRHLERTGYKFTVFSNLDNTTQLRLLSKEDEIRFWKKNSIKSTLLAIICMLLYMIVPMMWPTIVQDRIFPYKETSFVRGLFYRDILGVILASYIQFSVGFYFYKAAWASLKHGSGTMDTLVCVSTTCAYTFSVFSLVHNMFHPSSTGKLPRIVFDTSIMIISYISIGKYLETLAKSQTSTALSKLIQLTPSVCSIISDVERNETKEIPIELLQVNDIVEIKPGMKIPADGIITRGESEIDESLMTGESILVPKKTGFPVIAGSVNGPGHFYFRTTTVGEETKLANIIKVMKEAQLSKAPIQGYADYLASIFVPGILILAVLTFFIWCFILNISANPPVAFTANTKADNFFICLQTATSVVIVACPCALGLATPTAIMVGTGVGAQNGVLIKGGEVLEKFNSITTFVFDKTGTLTTGFMVVKKFLKDSNWVGNVDEDEVLACIKATESISDHPVSKAIIRYCDGLNCNKALNAVVLESEYVLGKGIVSKCQVNGNTYDICIGNEALILEDALKKSGFINSNVDQGNTVSYVSVNGHVFGLFEINDEVKHDSYATVQYLQRNGYETYMITGDNNSAAKRVAREVGISFENVYSDVSPTGKCDLVKKIQDKEGNNKVAVVGDGINDAPALALSDLGIAISTGTEIAIEAADIVILCGNDLNTNSLRGLANAIDISLKTFKRIKLNLFWALCYNIFMIPIAMGVLIPWGITLPPMLAGLAMAFSSVSVVLSSLMLKKWTPPDIESHGISDFKSKFSIGNFWSRLFSTRAIAGEQDIESQAGLMSNEEVL
The following text describes a protein:
Function:
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis and membrane trafficking in synapses. In response to high synaptic activity at neuromuscular junctions, plays a key role in promoting efficient synaptic vesicle recycling and re-formation through early endosomes.
Subcellular Localization:
Synapse. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Note=At the neuromuscular junctions, present at both pre- and postsynaptic compartments where it associates with cytoskeletal neuronal microtubule structures and muscle Z-lines.
Sequence:
MLKSSNINSVLNELPNDPARDSTAQSSHNGKPKQDAETCCSSQDNEVMASLAALQLSAGVLQIAEPPLNHVRTQLRELIGRQNKTYIDLSKEKYKLDCSEVARLNDMMSDVKRYKDKLTKIKKEMQGVYQRTKELKKRAANVAACKQRDYQRKLERLQHEESLIGSQ
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MGKDRNNNRGPKFNPSSSGEAGSLLPGGFIGFSAFTTNLTNATDPDYYQVDPEYQVLLKKLQKKDSISRIKGLEELNKLFSKINIESPEFNPSSIKPLMNAWEFMYRRLVNDDDRHVRDLANICLGSIGSRIGKHMGPHVKVLLGPWVFSICDQKDQAVNSALNSFNNIFPEKKQKDVYKFGHDEALTYLCENLQETPQTIGDSKSVTPEVLQDRYERCISNSLLAIDYLINKTQEDTTTSTSTSTSTTTTDTNNKNLEIYENIFESQFFSFFQSKSSLIRKTSYRVLTTIINKLPMFVEKNFKDFSSKVLGLFSEKDSTTHLFMWEGVISFLKKYGDKAWDQVDVRKHVLPRLWSFFKSGCYGSYDLSYPSILPLLTFIPSSVIGEGTAFFKEFFGNLFKGLEVLDNVRLYGNPNNQDRPSNLMLSCYLECIVYSSKKWGSQQEEVNQYLIQDLFGSFYRDYFNLEYCSFTKSFLVTKLLETTRKLSSINEQLNVPQLEALFKLNVLNDVFVNLIKAEKEKQPETKEEKLVQSISNETFFDRFNLFLSYSSMSSGGNPSNNLVFIQEFIKRLFGLACNGLSVHQEYSIKMIDIILKNYKISQILLTTNDFQNFFSNTIVPSLNKAISEQNKQLVSNLISITITLLTAILKENNDQKDFNQYWSTILNVFINDRSGMINGSASLGLEAELSKLINTISSQETTSEKRSWLSNQLLDKLTKSIISNCNDNDEKEYKPIVPGDVIERLIKCLSSKLSQLMETIEMNLLLDFNLDYLVGLSLMVLSIDDYNQQLEPIKGLISQWIKFIIEIHHRPNLQSLYSKDLLSINNQIIATKYKDTNISTLIINLIIEYVEKLSEPDLDYLSNQLVQLINNNTDNNSCLDNLFKHYSNNNSNLVSQIKISWFRYNKVLPLYLITDKQPTTLNQQQVNQLFKTIIFNFNIINSIGFDEVTKYLISSPNTSLIINQILSCFIFINNDNKLEEGQQLPTYYYQVMNFIDITSSSFINNFIKSLFKFEDKSIFSTEWFKKLLNGATTSNSSSNQQIINLLSVKLFVDYLTKEEEESEEAKKYFHLLLEQASIFENFKKSNLTVQELNFIQILLPILSTSASSKDLIQFYKESLYEKISNITPSIPNDFTPTIVHLSLLSSILLQEQMNGNKEISSLISEKEFSVLLNGLQMIQQWYQKLKSPLLKDASENNKELELVLLNFIFIIIQYSLCKKSNLPSNLSQLVQSLLTVWLTNTIYDNEPLSNINNNTEQLNQLINYQSLKIYNLLLSNDNIKYIIPGSDQFIIDHSILVLNNWLHLSSSPLTSNSHLLELYSNTFEKMDSDIRYKISLTKIDNIISLLYSTSRGIQKTAYTILESYFSNENSQLVKSFLLSDNPEDDDDEKVQFIVFSKEFERILLDFDSSWKELKKNKNSSTINIKCVGQLILWNLLLKNYSKLDLNKRSVVNGWLNQTHKVSQLLNYIFTFAKKDEQPNYNYSEFPFNEIEENENNINNNITNITFRYSTIQMLCSHCIFSLVNYLPNMFRRWADDCSTNSKMNQQIQNYVTNYISPLIIQNEITRVNNYCDGKDSNFTVKGSTSTKEVIASYEKDDITISLVLSIPDTYPLRVLTVEFSKRVGVTESQWRQWLLSMTSLLLTQDGSVLDACLLWKNSLDKHFEGVEVCPICYSMFHNGTIPKFQCKTCRNKFHAGCIYKWFQTSHKSNCPLCNTLIEN
The following text describes a protein:
Function:
Integral membrane transporter that imports quinic acid to be catabolized as a carbon source.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKIYNVYFLCSFITLGGGLFGFDISSMSGACPGNSGVCELLPRGQRPGGITCAMPFGSLIGALCSSFIADRYSRVTAIQFSTVLWTIGSIFMTASNGIALLVVGRVIAGLCVGIASAMVPVYQAEVAPKEIRGRVISLQQWAITWGILIQYFIQYGSSNVDGGPDNPTQSTAAFRIPWGIQMVPGFILFVGLFFYPKSPRWLASKDRWDEAMEVLANLHGNGDRNHPKVLAQYQEIEEALALEREQASTSYQELVKPRILKRVFLGMSLQMWSQLCGMNVMMYYIVYIMQSTGTGSPLLTASIQYILNTALTLPAIIYLDRFGRRPAILIGFALQATFLYIEGGLQAGFGKPNPHDDPKLDAISWVVSDHPNVGKAIIALSYLFVCSFATTIGPTSWTYPAEIYPAKVRAKAVSLATASNWIWNCLLALFVPPLLWSINWKMYMIFAAFNTAAFIHMFLMAPETKGYTLEEMDEVFDSGLPAWRKLNKRSRLEELEQEIAQGKLKVAAHSEKDGPVAATTETV
The following text describes a protein:
Function:
Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
Sequence:
MSQTTEQLEKSDIKDILENSLNGKRPGPEDCMRLLESDDVHLMGLVSGHLTRKQFGKKASFVNNIILNYTNVCITDCKFCAFYRSPGADDSYTLTLEQIESRVKTAWDMFKIRQVLIQGGHNPNLKIEYYEDAFRMIREKFPKVGVHGLSTSEIDMIARVEKSSTKEILSRLKDAGLQSMPGAGAEILTDSVKEIISPKKISSDAWIRIMNEAHSLGIPSSATMMYGHVENKNDIVEHFFKLVKLQEKTKGFMAFIPWNFEPNNTLMHEEGLVEYGTGGIQLLKMIAISRLIFDGLIPHIQSSWLTNGIGMAQLALQYGADDFGGTLIGEEVVSCTGARSTELTDKIIMDAIHQIGYSVEERDNFYNPISVS
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
Sequence:
MTEKHTTPDGLVIVDKPSGFTSHDVVAKMRGIARTRRVGHAGTLDPMATGVLVLGVERATKLLGHLALTEKEYLGTIRLGQTTLTDDAEGEITGSRDASKVTWEAIDAGVAELSGDIMQVPSKVSAIKIKGVRSYKRAREGEEFEIPARPVTVSSFAVYDVRDAVADDGTPVLDLVVSVTCSSGTYIRALARDLGAGLGVGGHLTALRRTRVGPYKLDGARTLDQLQQELTVMPVADAAGAAFPRWGVDARRARLLANGVRLEMPEEYTGVGAVAVFDPEGRLLALVEEHKGKAKSLAVFG
The following text describes a protein:
Function:
F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity).
Subcellular Localization:
Cytoplasm, cytosol.
Domain:
The KEN box is required for the association with the APC/C-Cdh1 complex.
Sequence:
MGSTQSVSGTPARPLPRNKHVSRVADPRSPSAGIQRTPIQVESSPQPNPPAEQLNSLKQAQDPDPRSPTLGIARTPMKISGPDSQCPLVKELSEVFETEVSETEVSESISSPVLGLPQETPLSSELDLPPDPDPQVSLEDQLLPWSQTELNSKQVFAKEEAKQSTETMVSGQTSDKPSRDPETPQSSGSKRSRRKTNNKVLGRSPLTILQDDNSPGTLTLRQGKRPSALSENVKDLKEGVILGTGRFLKAGGGAWEQNEDHDKENQHFALMES
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MRYVGICKFATLHSTIPASAWARRLGRSPHGFLPYVKATVPAVHLAHTRPVTGFIFATVNRRAPELYPPVVHPKAETEAGVKGRGKGKKKKANQMAKSKAKKEANAHSQPAACVSVGAFIGGKSKSKVGKLSKKQRKRVAAAAAAMPSQMQADSTGPHGTSSQGSALSESAQPYPASAWNNGTLRMGGGNFEVDQNGFPTDASSPFPGLNPPTGNFGTLGFNPLAPPFTQQLPRGLPRGRGGSHQTPISTRNERRQKNHGKHDQQKITLPPSAASGGVPNPTPEYLNLASEKPIRLESPKPILIVLDLNGTLLFRPSRNPQAFVARPHALTFLNYLLSRFWVAVWSSAQPANVGAMIDNLIKDKEQRDRLVAIWGRDRFGLSSHDYAQRVQVYKRLTRLWVDPDVAASHPGIAQGERWDQSNTILVDDSTEKARSEPHNLVRVPEFVGDLNESPEVLPQVHDYLNELSFQRNVSSYMRATPFVMQ
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MYKNQPVSKDNVVFIGFCCVGSAVCIVLLIVLLLFLCTGCFICLTILFSFLALGAVIALTVIKGNLAARITLPIYCFIFPLLFCFKLCGKIRFSTCVLKSAVLLASKFPSTVILTLFVVILQAALNYAFEVGTVAVYYHDVSPWVYIWVILSYFFLTNTIKNFSYTVIAGVSSCWYFLNESPDMPRFPFWISFRHMIGPSFGPCALGGLLQGICDTINEVNDTSKTNPLFCIINCMCLCCKCIVTVLLLIVNRFALIYCAMFGVSTKDGVKRWFKQKSRKMVKQCIVATVIKATFDTYSWVSSSVCGAVASFFAARKYGVDSPEYVFSVIMGTFFGKQAVVFIGRSYYDNE
The following text describes a protein:
Function:
Strongly inhibits juvenile hormone biosynthesis in vitro by the corpora allata from fifth-stadium larvae and adult females.
Subcellular Localization:
Secreted.
Sequence:
MKTSAYNVYLGVVAAMLALLFVTINAAPMEADDETAENTLVAHPDGDMELSGPWDAINTAALRKLLLQLDAEDRMGGVTRSWPQAEPRGWGLRALDSRLARQWRADKRQVRFRQCYFNPISCFRK
The following text describes a protein:
Function:
Plays a role in the initiation of viral DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA. E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome. Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box. Repression occurs by sterically hindering the assembly of the transcription initiation complex.
Subcellular Localization:
Host nucleus. Note=Colocalizes with DDX11 at early stages of mitosis.
Sequence:
METACERLHVAQETQMQLIEKSSDKLQDHILYWTAVRTENTLLYAARKKGVTVLGHCRVPHSVVCQERAKQAIEMQLSLQELSKTEFGDEPWSLLDTSWDRYMSEPKRCFKKGARVVEVEFDGNASNTNWYTVYSNLYMRTEDGWQLAKAGADGTGLYYCTMAGAGRIYYSRFGDEAARFSTTGHYSVRDQDRVYAGVSSTSSDFRDRPDGVWVASEGPEGDPAGKEAEPAQPVSSLLGSPACGPIRAGLGWVRDGPRSHPYNFPAGSGGSILRSSSTPVQGTVPVDLASRQEEEEQSPDSTEEEPVTLPRRTTNDGFHLLKAGGSCFALISGTANQVKCYRFRVKKNHRHRYENCTTTWFTVADNGAERQGQAQILITFGSPSQRQDFLKHVPLPPGMNISGFTASLDF
The following text describes a protein:
Function:
Glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where its binding to self markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop. As a cofactor of the serine protease factor I, CFH also regulates proteolytic degradation of already-deposited C3b. In addition, mediates several cellular responses through interaction with specific receptors. For example, interacts with CR3/ITGAM receptor and thereby mediates the adhesion of human neutrophils to different pathogens. In turn, these pathogens are phagocytosed and destroyed.
Subcellular Localization:
Secreted.
Sequence:
MKLLAKIICLMLWAICVAEDCKELPPRKNTEILTGSWPDHTYPEGTEAIYKCRPGYRSLGNIVMVCRKGEWVALNPLKKCQKRPCGHPGDTPFGYFSLIGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVKPPENGKIISGAMEPDREYYFGQVVRFACNSGYKIEGDNEMHCSEDGVWSKEKPKCVEISCKSPDVIHGSPISQKIIYKENERFQYKCNMGYEYSERGDSVCTESGWHPLPSCEEKTCNVPYIPNGVYSPLRIKHRTGDEIRYQCINGFYPATRGNIAKCTSTGWIPAPRCSLRPCDYPDIKHGGLYYESMRRPYFPVPVGKHFSYYCDEPFETPSGSYWDYIHCTQDGWSPAVPCLRKCYFHYLANGYNENNGRKFVQGNTVEVSCHPGYSLPKEQTTVTCTENGWSPTPRCIRVKTCSKSSIDIKNGFISESQYTYALNKQAKYQCKLGYITADGETSGSITCRKNGWSAQPTCIKSCDMPVFKNARAKNNITWFKLNDTLDYECHDGYESNTGSTTSSIVCGDNGWSDLPVCYERECELPKIDVHLLPDPKKDQYKVGEVLKFSCKLGFTRVGPNSVQCYHFGLSPDLPTCKEQVQSCGPPPELLNGNVKEKTKEEYRHSEVVEYYCNPKFLLKGPNKIQCVDGAWTTLPVCIEEESTCGEIPELEHGYSELSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVATDQLKKCKSPNSIVIVENLTSKKEFDHNSTMRYRCRGKGERLHAVCINGRWDPEVTCSMAQIQLCPPPPQIPNSRNMTTTLNYQDGEKVSLLCQENYLIKEGEEITCKDGRWQSIPHCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEYGFWLSEENEITCYMGKWSSPPQCEGLPCKSPPEISHGVVAHTSDSYQYGEEVTYKCSEGFGIDGPPIAKCLGEKWSHPPSCIKTDCLSLPSFENAKPMGEKKDSYKSGEQVTYTCATNYKMDGPSTVTCINSRWTGRPTCRDTSCVDPPSVKNAHIVSRQMSKYASGERVRYECRSPYEMFGDEEVMCVNGNWTEPPQCKDSTGKCGPPPPIDNGDTTSFPLSVYAPDSSVEYKCQDLYQLEGNKRITCRNGQWSDPPKCLHACVISPEIMEKYNITLKWKAEEKLYSRTGEPVEFKCRSGYYLSSNSHPLRTTCQDGKLKYPTCVKRHYRS