lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
Subcellular Localization:
Nucleus.
Sequence:
MDKYRLTPHKITICVLVEYYLNGTIKYHQKQSLSHLLIRHIKENNYQDTVKEVSLYDFIEKELKYVLPIQFINNEFLRMIQFDSVDDIYQFMSSLKELFNGSNDHESINSKQMQLLDSKSILGIFIKKVILNFNQILFDGLIKLYDQLDQYLNDFYNEINKIQQQQQQQQQKEHCENDNSIDMSMDQEQQQQQQEDYNEISNYENKIKFLSPLDEERFIYEETIRINSLIGIETPLEIENQVNRLKASLPNVKRVHLISLLFNIGYQDYDQSLEDLHRYFDYVNGQMTSSQWSSSASSFLFTPNDNYQSGNSNSSNYYYNNYNFIGGSGDTTNLMLPYAVLNLVRLHYHFGHYEESYLALREAIRIAQERADHSCLALADHWLARLLKKSVYNSMESSNLLQYLLASHSDSEILKKSIERSRDLEMPDLLALNHTAFSKYKLENGEFSTNINSNNYNSNNNNNNNNSNTNNNTNNNNNTNNANNNNNNNNNNTNNTNNNNNNNNNNNNNNNNNNNNNNSSNSNNNGGVNMFGKSFHLWNDIFQPIEISRLLDKSSSTAMIAHHLYSSSWELLGNNDLAQFFTELAMKSYHSNDLSLQHDPLRAVSSQNTIIYNIGTNNNNNNNNNNNQIKQQQQQNQQPPDLLSFCKLALLYSKKSKYNEAIQILIKCFSIYKTQHLCGNLLTFTVLSILFDHLMINIDNNNNNNNNNNNNNNNNNNNNNNDNELLISIVIESLINITNRFQSEDSVDGSGWSQIVICYQKIIKYYCNVRGMYEKSMNLIVKGIQISRDFGLDSQITHFYSLLSKIYEKSSPYRFSGLSDTLSALSLSNSYHLANSIADSNIALIKIHLSTDRLDKAITLIKETLPMVLSDKLLNSQLYLLWAKSLISTSTKQSIDYLNRSEQLFLQLFSNQSNNNNNNNNNNNNNNELLKEIYYLKSIIYNDLGDIENRNLYAKKFKSILVPSSSIQQQQQQQQQQQQQQQQQQQQQQQSNQSPVINSVQPTPKICLVPPILMKIR
The following text describes a protein:
Function:
May be involved in spermatogenesis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MTDFSIAKFNNYQEYLHSFTTVEDFRYLPFHKTVITLTKLGYREHRTFYEEDEFLNVKKQVEQLLNPTVSAQIYYSQYFKGTDPALWALAEREHGNVQQEISTIIFLEISGRSGFSKSGYIDFEASLRNYRFKGPNAVDWKAVFEERKLLKPQPSDIVFYDWKTRKIFANDNDNYTVVAHPEHGLMFAHKGDHKNIPVTTKKNPFSSNVRRSMIRSNLYGFIILYDHHVRKKT
The following text describes a protein:
Function:
Inactive carboxylesterase-like protein; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity. The first step is performed by the polyketide synthase VdtA which condenses one acetyl-CoA and 6 malonyl-CoA units to form the heptaketide monomer backbone of viriditoxin. The product of VdtA is then O-methylated on C7 by the O-methyltransferase VdtC. The O-methyl group is important for the stereoselective coupling of the monomers at the final step of viriditoxin biosynthesis. The short-chain dehydrogenase/reductase VdtF then acts as a stereospecific reductase converting the pyrone to dihydropyrone via the reduction of the C3-C4 double bond. The FAD-binding monooxygenase VdtE then converts the ketone group into a methyl-ester group to yield semi-viriditoxin. Finally, the laccase VdtB is involved in dimerization of 2 semi-viriditoxin molecules to yield the final viriditoxin. VdtB is responsible for the regioselective 6,6'-coupling of semi-viriditoxin, which yields (M)-viriditoxin and (P)-viriditoxin at a ratio of 1:2. The non-catalytic carboxylesterase-like protein VdtD affects the stereochemistical outcome of the coupling. The highly reducing polyketide synthase VdtX is not involved in viriditoxin synthesis, but might possibly play a role in the production of additional metabolites not identified yet.
Sequence:
MFMTQIVFGIAPTLLKTFSHLTALDLWRPSAPYVFDPVTSSTYLGTIADGVEEFLGIFYGQDTGGSNRFAPPKPYIPSRHSFINASTAGAACPQPYVPLPADPYTVLTNVSEDCLSLRIARPENTKSTAKLPVMVWLYGGGASVGTAYDVSYNPVGLIQQSVVNGSPVIYVAINYRVNLFGHAFSDALLKSKSTNLAMQDQRLGIEWIKNHISAFGGDPDNITLFGEDEGATYIALHILSNHEVPFHRAILQSGAAITHHDVNGNRSARNFAAVAARCNCLSDGDRQVDSQDTVDCLRRVPMEDLVNATFEVAHSVDPVNGFRAFMPAVDGYMIPDEPSNLLSRGQVPANISILAGWTRDESSMSVPTSIRTAADAASFISTQFPLLNASTIHHFLTSLYPESDFTTNSPSSPEKVTPAWRATSALHRDLTLTCPTIFQAWSLRLSSNCTTPVYLYELRQSPFATALNNSGVGYLGIVHFSDVPYVFNELERTYYITDPEENKLAQRMSASWTAFASGAFPLCERSERSLGRWEEAYGGDRVCRDRMPEHVRVKGIGDNGDQDDGDEIGKLMARCGFINRLEY
The following text describes a protein:
Function:
Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known (By similarity).
Subcellular Localization:
Cell junction. Nucleus. Cytoplasm, cytoskeleton.
Sequence:
MMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSGGGGGPGSGPGAATSASAAAVTVADSAVATMENHQHGAQVLLREEVVQLQEEVHLLRQMKEMLAKDLEESQGGKCSEVLSATELRVQLVQKEQELARAREALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAAALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKSLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCSPTRHSLSLSEGEEQMDRLQHVELVRTTPMSHWKAGTVQAWLEVVMAMPMYVKACAENVKSGKVLLSLSDEDLELGLGVCSSLHRRKLRLAIEDYRDAEAGRSLSKAADLDHHWVAKAWLNDIGLSQYSQAFQNHLVDGRMLNSLMKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREALQERRARCETQNTDPVVWTNQRVLKWVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAMATALGIPSGKHILRRHLAEEMSTVFHPANSTGIRESERFGTPPGRASSITRAGKEDGSSNSKYRTGRLPLGKIGRGFSSKEPDYYDDYGSLENEDCGDDDLQGRPEQCRLEEYSSLEVTNV
The following text describes a protein:
Function:
Has thioesterase activity against fatty acid thioesters with 14 -18 carbons, including palmitoyl-CoA, S-palmitoyl-N-acetylcysteamine, and palmitoylated proteins. In contrast to PPT2, PPT1 can hydrolyze palmitoylated proteins and palmitoylcysteine.
Subcellular Localization:
Lysosome. Secreted. Golgi apparatus. Endoplasmic reticulum.
Sequence:
MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG
The following text describes a protein:
Function:
Chaperone of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells, facilitating the establishment and dissemination of infection. Along with PscG, prevents premature polymerization of the PscF/SctF needle protein within the cytoplasm. Required for type III secretion needle assembly. Also required for cytotoxicity by influencing PscF/SctF levels.
Subcellular Localization:
Cytoplasm.
Sequence:
MMTALETRLSVADGTHAAALRQRLQAALAECRRELARGACPEHFQFLQQQARALEGGLGILSQLTED
The following text describes a protein:
Function:
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Subcellular Localization:
Mitochondrion.
Sequence:
MTRSAVTRALRSIPRATILSRPPQLPRTPSFRNRAPPSLANYNTRNLSVTARRLSDDDDERKWSTPLAKQLAEAITATGPVPLASFMRMCLTGDIGGYYTGAIEKSEQNRDQFGAKGDFVTSPEISQVFGELCGLWYVTEWLAQGRPSKGVELIEVGPGRGTLMDDMLRTIQNFPEMAKSIDAVYMVEASPQLRMAQKNLLCGKDAAMSESKVGYHSHCKYGDIPIVWTETIKSIPYDPEKTPFIMAHEFFDALPIHAFQLVQVPPTEPASPSSIATITTSGPKQSKQSRPSGSTGPILEWRELLVSPTPPFSTHTTLRTPASHNPHLTPPPDFQLTVSPSPTRHSLHLPDLSPRYRAIKSSSSPSSSSSSYPSQKPLAVLPDGTTQAGALIEICPDAFLFASDFATRIGGSPAHPKPSPRGAALILDYGPGDGSVPVNSLRGIRKHHLVSPFAEPGLTDLSADVDFTAIAEAATNASEGVEVHGPVEQAWWLEGMGGRERVEQLAKRSKRGNEEEEKDKFVKDLRRSWDRLVDRGPNGMGRIYKALAIVPENDGRRRPVGFGGDVVM
The following text describes a protein:
Function:
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MADKPDLGEINSFDKAKLKKTETQEKNTLPTKETIEQEKQAK
The following text describes a protein:
Function:
Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates.
Sequence:
MCQSSFGMSNWIPMGNRNAHGKKKRDIPVDDLLEVVKRFRNEELLVNKEGDEENSNMLPVGRPKEYKELPSGPLYPCAAASSEQNKTKDRYKNVIPYDNCRVILRSNPSGSDYINASYIDGYKEPKFFIATQGPLPETLADFWHMVWQEKSSVIVMLTALEEQNKVKCERYWPEEIQTYGDIRVSVESTSQTGAFISRSFTLQKVGDSAQRTVEHLHYLQWPDHGVPSKPSGLLQLMDQMNKCKLPGSGPVIVHCSAGIGRTGTLLALDILLKRARAEGKVNVYDCALQMRRRRPNMIQNQGQYMFLYDVLLETLVCSSTSLPVEGVLTHMRHMQTLDPGTNTSGFTREFQAVEKLTELYRICSYREAHENHCKNLHPDIIPGDHCRPILMSVMDQHGAPGYINAVFINSNSQEDQFIVTQLPKLETLPDLWSLVWDYRCTSIIVMHPAQDIRRLCPHFWPVSGESTYSNFQVKKISSLRDSGFSGATLHLQHKKEPILEVQLWHLDSWPKDKPVPQNPGAIISLIGKVERLQQQDKESHVLVICSDGATRSGIFCAGSLICDQIRSDGFLDVSQSVRSLKKRRRQLIPNVDQYSFCYSLAKTYLDSFETYGNFQ
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MDAGGGLVSSAKSILEKPLKLLTEDDISQLTREDCRKFLKDKGMRRPSWNKSQAIQQVLSLKALFEPGDDSGAGILRKILVSPNPTRVTATSAEPASEVGARIPFQEDDRRDSPRSAEFSGSEKDSYNTISPSRSPAETSALVGQMTIFYSGKVSVYDGVPPEKARSIMHFAANPIDLPEYGVSASARMTSRPMSSKEKMVEPPHYGLEKANASRDSDAEGQANRKVSLQRYLDKRKDSRRLFKNKKAPGVASSSLEMYLNRSQPVTNAYSQSLSGGGTGGEQHESPENQRRSPNLSVDLNSDLNSEGVEQEQLKRRQGMFSSSETWHKKVELEES
The following text describes a protein:
Function:
Magnesium transporter that may mediate the influx of magnesium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MRARGVGKHGVGIIEEERDKERHVLGLRVKKGLGVRTWLLIDVKGSAQVVEAGKHAIMRRACLPARDLRILDPQLSYPSTILGREHAIVVNLEHIKAIITAQEVLLLNFKDDSVAPFVRDLRKRLPVHFNALGQEVHNDDGGGGLSDYEGDGHQKFHSHSPDKPLATRLCTTKADKEALMEVPKLEAQTGEANKFSSFPQYDDDGSPGRARGGPNILPFEFRALEACLEAACSSLDNEALDLEKEAYPALDELTSKISTLNLERVRQIKSRLVAISGRVQKVRDEIEQLLDDDGDMAEMYLTDKLLAQQEGSVSPSSPGPGFGSVSPGADSHTTHLPFNPDDPTLQSDGQVSDDEDGVNGGPESLANGRIHGSRSSSSTSTVSAKPLDVEELEMLLEAYFVQVDGTLNKLSTLREYVDDTEDYINIMLDDKQNHLLQMGVMLTTATLVISAFIVVTGVFGMNINIPLFNIGGTPQFLAIVFGSAAICVVLYFAVIGWCKYKHLIE
The following text describes a protein:
Function:
Plays a role in the bacteriolysis. Is activated under conditions of high osmolarity by the factor sigma S. Entericidin A functions as an antidote.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAATKAQQ
The following text describes a protein:
Function:
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Subcellular Localization:
Nucleus.
Sequence:
MLSRLQELRKEEETLLRLKAALHDQLNRLKVEELALQSMISSRRGDEMLSSHTVPEQSHDMLVHVDNEASINQTTLELSTKSHVTEEEEEEEEEESDS
The following text describes a protein:
Function:
Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose. Known targets include Notch proteins and coagulation factors, such as F9.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Sequence:
MXXXXXXXXXXXXLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAPAAPSPPALELARGSVAPAPGAKAKSLEGGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKHFSAGSGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRHTFWQFRHENPQTRVGGPPPEGLPGFNSGVMLLSLEAMRQSPLYSRLLEPAQVQQLADKYHFRGHLGDQDFFTMIGMEHPKLFHVLDCTWNRQLCTWWRDHGYSDVFEAYFRCEGHVKIYHGNCNTPIPED
The following text describes a protein:
Function:
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-mannose and L-lyxose, but at reduced rates.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPNFWAYYSSFSLSTRLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLISTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKSLIIHNVLLSTLGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVAANIVGIGMAN
The following text describes a protein:
Function:
May participate in a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MAKRGYKLQEFLAHSANVNCLSIGKKTSRLLLTGGDDCKVNLWSIGKSTSLTSLCGHTSPIDSVTFNTEEALVLAGASSGVIKLWNLQEAKVVRGFTGHISNCSALEFHPFGQYLASGSSDANLKIWDIRKKGCIQTYKGHTRGISTVKFTPDGRWLVSGGLDNVVKIWDITAGKLLHEFKFHDGPIRSLDFHPLEFLLATGSADRTVKFWDLETFELIGSTRPEATGVRSIAFHPDGQTLFCGLDDGLKVYSWEPVICRESVDMGWSTLGDMCINENKFVGCSYYRNSVGIWVSDISKLEPYGAGSEDENECMVKRFSALDEQASERMKSGSRGSSSPDYETKEIKNIYVDSIGGNLKAAIRKSEKQNADDKSSRMHSVVDSDSGEESSHSRSESVASSKTSPGMMLRPAHVRKTLAKFEESASVHSGTRKKSSQDVEEETQTRNAEDSTIKGIMYKFEKALSSEPPTDEATRMLHKPPRVQRSSYNNNYNESRRAMSVDSATSNDSKAEYSGDLPSGKNLCKTERVVSPEKPGDEQTIKVVSGRTRSLVERFERGEKITHTEEADNTNAVEQDPDKTSRQAGETPVTHVSSQTDSDITENLMQTHEEFLSTLQSRLTKLQTVRHFWERSDVKGAIGALRKLTDQSVQADVISILTDKIEILTLDMFSQLVPVLTSLLGSRTERPVNVSLDMLLKLVAVFGTVIRSTVSAPRIVGVDLHADERIQICQVCSAGLHKIQRILPILARRGGLITRKAQELNLVLQQT
The following text describes a protein:
Function:
Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase.
Sequence:
MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELGLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
The following text describes a protein:
Function:
Catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate and carbon dioxide with the concomitant reduction of NADP(+).
Sequence:
MSMLVRAVRGTSQPTLLASRSMMSAASRSNPDAYDEHGNRRVTVAYGDGIGPEIMEATLRVLKAAGAKIAPEIVEIGEKVYERGVSSGIDKDGWESLKRTNLFLKAPITTPLGGGVKSLNVTVRKTLGLYANVRPVKSYAPFVPSLHDNIDMVIVRENEEDCYAGIEHRHTSEVTQCIKLITVPGTARVCKYAFDYALTHGRKRVSCITKQNIMKITDGLFHRVFKRTADQYPTLESEHRIVDIATAQVASKPHLFDVIVTLNLYGDIISDVAAEVAGSVGLCGSANVGDRAAMFEAIHGSAPDIAGMDIANPSGLINGAIMMLGHIGQRDVAVTIKNALLKTIEDGIHTADIYREGKNSKQKVGCQAFADAVIERLGQLPVILPAEEIDLDSDSVDVPTFELPERPVFTPPSKSLVGCDIFVDWEGTGRDPNILAQHLQACEGDHLKLEMISNRGVKVWPDGNPNTYKVNHWRCRFTSNSRDHLPSNTHICELMRRMDNSRLDVIKTENLYDYNGEAGYSRGQGHCDGGLSPSVCLLTLSLLEDRAMYPSLMFAAVRTAAMRVTGSVRFASAKAAAPKKDIVRDTFADKLKEYGKKHAKSLDDRVAQVLAERMGVAKKA
The following text describes a protein:
Function:
Essential for segmentation and CNS development. May modulate the actions of other transcription factors, including gap and pair-rule proteins.
Subcellular Localization:
Nucleus.
Sequence:
MATLSTHPNYGFHLGQAQGLEDYAPQSQLQLSPGMDMDIKRVLHYSQSLAAMGGSPNGPAGQGVNGSSGMGHHMSSHMTPHHMHQAVSAQQTLSPNSSIGSAGSLGSQSSLGSNGSGLNSSSGHQSAGMHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAGPQGGLQMQAGGMGQQKLGAGPGAGAGGYNPFHQLPPYFAPSHHLDQGYPVPYFGGFDPLALSKLHQSQAAAAAAVNNQGQQQGQAPPQLPPTSLSSFYSGIYSGISAPSLYAAHSANAAGLYPSSSTSSPGSSPGTITPNGMDGSMDSALRRPVPVLY
The following text describes a protein:
Function:
Required for pharyngeal pumping.
Sequence:
MGEEDWSDTQQQPRKRWTLEQLKGGNTFLSQQAGTNKFETQKGMTAVGMPRWNITKDKKQGYIAPDQRSENVLRVQCGTNQYASQKGETPIGASRFQVPKVTYKKEWETILDKEGEKIIPKQAGDYGLASQAGEVSMGGHRNQVALIRGRLPHDRRTHGVLCFQNGTNLFASQTGMSAPPGLGAVRQATQKIEGLELGEDILRRGTEFTPWYSGQNKFATQAGSGGFLKVRDVLPHTVGGKDIEEELKQKSEGIVPLQSGTNKLASQRGMTGFGTPRNTQLRAGWKKEWIEDYEAALKEWEETKPPGSASSVDPFGHYKKKFEERESSRQSEIDSQSVKASEPVEPEPEEEEEEEEEEKIEEPAAKEEEEEEEEEEEEEEEELEEEEEEEEEEEEDE
The following text describes a protein:
Function:
Inhibits cell growth by regulating the Tor pathway upstream of the Tsc1-Tsc2 complex and downstream of Akt1. Acts as a cell death activator during head development.
Subcellular Localization:
Cytoplasm.
Sequence:
MKMDVIAREQIIYGSLQGSNKNKDWTSRLPPPSAYTLDLMSKKAKTTTGGSSNGSNATATSTTTSTSSSIKHKQPAGSSNNNVGQSQSKKTKPSGSYNSNSNYYYYAADEEEGGSADYALSNYDKKAVEELSLRLLDELRAAKSRHLTCTEVSLPCDLTPSVAREIIRVSEKEPRGIRGCTIYIEFEDEPKNSRRIASIKVDSDTVSTFEVYLTLRQDHRGWTSLLPQFMKSLARTITISPEYTITKNKLYSADGLGARRSYSFGSHAHRPSAAIATPTN
The following text describes a protein:
Function:
The first enzyme leading to putrescine and thus polyamine synthesis.
Sequence:
MSKLKIAVSDSCPDCFTTQRECIYINESRNIDVAAIVLSLNDVTCGKLDEIDATGYGIPVFIATENQERVPAEYLPRISGVFENCESRREFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEALFRADLCNADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPVYLETARNPYGFIGGIDAHCFEESYLRELIAEVAPQRAKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCSPLLLDLNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYPLFAALNINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFQFVPGEHWHSFEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLVRFEKLLESDAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPRDAQSTLLKGEKL
The following text describes a protein:
Function:
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
Miscellaneous:
MISCELLANEOUS: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSWLEAMILGLIQGLTEYLPVSSSGHLAIGSALFGIQGEENLAFTIVVHVATVCSTLVILWKEIDWIFKGLFKFQMNDETRYVINIVISMIPIGIVGVFFKDYVEAIFGSGLMIVGCMLLLTAALLSFSYYYKPRQKDKISMKDAFIIGLAQACAVLPGLSRSGSTIATGLLLGDNKAKLAQFSFLMVIPPILGEALLDSVKMMKGEDVVGDIPALSLIVGFLAAFVAGCLACKWMINIVKKGKLIYFAIYCAIAGLAVIITQL
The following text describes a protein:
Function:
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.
Subcellular Localization:
Cytoplasm.
Sequence:
MRMPLILQFILPLASCLIGTSRAFSPVQRQPNTAHKTCTVSASIIIDIDTPSTPATTPSAEYEDPFNLLTTLAATTLLQSDRRRDAIGKETGAQASSATNWIDEGSAFRLRGVLDGMMLWLPGQQHTNGGGVGASVVGSRERQDEAITWLRWMRSVPRPMVVDLSLEARKAANETVSDDFLKLLNLGGGTVDDTDGNATTTTTTTTTSNKAISKAKMQQIRNEFLNRIGCKLILLPSGQSLQGGLLEPAGSLVFGKLLYGGVTRYRILPSSNNNSNGSNTSSPKPPRRAGERTERKSSTKQHIPSWVQYGGTERKYDGVDMGPALILELSLMPKIQSGSDGGGGGGSSEKSMHVKGDMVLKRLAWSPHRMFCYVADGEEGARNNNNLANGNQTTTQQSGVSMTLHGKERNDAFASDFRSRVGGLGPQIDSIVRRVLDGRVIRPAEVDESGEMLSYKEAISQTKSQDGFAMDGASKQLSLAALEASELALLGLNPVKGCLLYGPPGCGKTALAREIARALKARAPKIVSAPELLDRWVGGSERLVRELFYDAEAELAACNGDATKSALHVIVIDEIDAVFRKRSSAEDSGEATRSSTVNQILAKLDGVESIPNVLLIGMTNRRELLDEALLRPGRLEVQIEIPLPDREGRREILQIHFEALRNRGRLSHPLCCAIDGVAPSYSKDSTVEQSISSPLAEDDSNQTRGRKRRALKRATNNIFDYLSPGKKGVFDLAADEVTGGYSGAELAGLVRCAGSIALSRARKDGAGVEALLITLDDIEQALTEVKV
The following text describes a protein:
Function:
This is probably a receptor for the plant hormone auxin.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MVRRRPATGAAQRPQLAAVGRGLLLASVLAAAASSLPVAESSCPRDNSLVRDISRMQQSNYGREGFSHITVTGALAHGTKEVEVWLQTFGPGQRTPIHRHSCEEVFIVLKGKGTLLLGSSSLKYPGQPQEVPVFQNTTFSIPVNDPHQVW
The following text describes a protein:
Function:
Guanine nucleotide exchange factor that promotes the exchange of GSP1/GSP2-bound GDP by GTP and controls RNA metabolism and transport. Involved in yeast pheromone response pathway and in mRNA metabolism. Involved in nuclear pore complex (NPC) assembly and required for mRNA and ribosome nuclear export. Binds chromatin and is involved NPC-mediated transcriptional control.
Miscellaneous:
MISCELLANEOUS: Present with 12100 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MVKRTVATNGDASGAHRAKKMSKTHASHIINAQEDYKHMYLSVQPLDIFCWGTGSMCELGLGPLAKNKEVKRPRLNPFLPRDEAKIISFAVGGMHTLALDEESNVWSWGCNDVGALGRDTSNAKEQLKDMDADDSSDDEDGDLNELESTPAKIPRESFPPLAEGHKVVQLAATDNMSCALFSNGEVYAWGTFRCNEGILGFYQDKIKIQKTPWKVPTFSKYNIVQLAPGKDHILFLDEEGMVFAWGNGQQNQLGRKVMERFRLKTLDPRPFGLRHVKYIASGENHCFALTKDNKLVSWGLNQFGQCGVSEDVEDGALVTKPKRLALPDNVVIRSIAAGEHHSLILSQDGDLYSCGRLDMFEVGIPKDNLPEYTYKDVHGKARAVPLPTKLNNVPKFKSVAAGSHHSVAVAQNGIAYSWGFGETYAVGLGPFEDDTEVPTRIKNTATQDHNIILVGCGGQFSVSGGVKLSDEDAEKRADEMDD
The following text describes a protein:
Function:
Key component of the cytosolic iron-sulfur protein assembly (CIA) machinery that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. Acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as rad3/xpd and dna2, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSSNLVALYLFSIDRSQDEANDVVDRIVEEIVTDRMGIVDLVTSIGEYLTDNNISVRAKAVLLLSQTLGELPKDRLPAKHVSVLLQFYLSRLDDEVTMKENALGIGALLNMQNFPAQKIVDVCKALFSSTDMPKYAQATRLNILKVFETIIDNYLFFISSQTRDAFFSGICSTFAGEKDPRNLMLVFSMLKKILSTFPIDGFEQQFFDITYCYFPITFRAPPDATNLAITSDDLKIALRETLVANDAFSKLLLPALFERLKASTVRIKIDALNIYIEACKTWRVGAYLWSAKDFWESIKQEILNSTDAELQNLALGALNTLASKFYKEEGFSSSFTEFVDMILIQLSQRLLEDVNVKSCGSCAAVFASLASISVETFNYCSCNFLPSVLDLPMVNEPLEKQKGMLVFLEYVYKCLVLLYGKWRSKNQADIDNPLLVYKDKQLSFVSGSLMGTAKDETEIRMLALKVIFLMASIKNFLTESELTMVLQFLDDIAFDFSDPIKKKATECLKDLGLLKPDFLLLTSFPFAFSKLTDDVTAKSSSEETFKQYLSVLVSISEERSLFKALVIRLVEMLKDQFKSKEMSVDLVESIVQSLSVAFKERNDRNEQEIPFFFEELLKQLFTLCFANCESMNVRCLIYVSQTINEIVRVNHFEFQEKFVGQLWKLYMENSNSDLIETEGCEKAAERFTLAASLSDQKFLNLVVLLQGGLNGLSKKLHFIEKLNIELLNLLINVVFVTESPGVKISALRLISSLINKCEKDEDISSFISSKGVTSLWDKVYTGTPKESEAALDVLAWVDKALVSRKHSEGIPLAFKLLDTLNLQNVGDSSVKALSIIIKDDPALSKENSYVEKLLYKQRFYASVSPKILEHISTATGGEKSLYLMLLSNVIGNVPKEIVIPDMPSILPLLLQCLSLSDISVKLSTLNVIHTSVKELTSLLTEYLDTLIPSLLAIPKDMNNPTVVRLLALKCLGSLPEFTPTTNLQLFRDKVIRGLIPCLDDPKRVVRTEASRTRHKWYI
The following text describes a protein:
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm.
Sequence:
MKLYGLIGACSFVPHVALEWVKIRENADYEFEPVTRELIKSPEFLSLNPRGAVPVLVDGDLVLSQNQAILHYLDELYPNSKLFGSKTVRDKAKAARWLAFFNSDVHKSFVPLFRLPNYAKDNETLAHTIRQQAVEQILDQLAVANEHLESHIYFGENISVADAYLYIMLNWCKAVKIDFSHLTQLSAFMQRVETDQAVENVRKSEELKV
The following text describes a protein:
Function:
Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi.
Sequence:
MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEELQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGESDTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCLLAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPRPEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQLPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKAVPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTAMDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEAGEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTEFSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPDLPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCVSQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVPPPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFGNLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGHTFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHFQLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRHGPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTADISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRASIAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALEAEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
The following text describes a protein:
Function:
Siderophore transporter; part of the gene cluster that mediates the biosynthesis of siderophore ferrichrome A which is contributing to organismal virulence.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSNQAQDQPERRDSSSENSSPFKDDEVAADQSVSAHGNTSLNKKDRVSAVRDADASSAREGQQPGVTRIEALYRIFPRNSPIVYTVYASLAAVTICFALDQSTTAAYQLYATRTLGSHAKLFGVIATVEAILNAVSKPFIAKICDIFSRQTAYFLVAVFYTIGFVVVASAQTPAAFAVGRIITEVGQAGFDLVTDIVVADLSPLEWRGVVTALTSSPFIVLPWVGNLIQARLNTGRPEGWRWGYGMFAIMAPVCVAPIILVLMYVDRKAQKAGELSFASSRLETRRAQEQGTVKVQRDSLRDRFANLVQLCKEMDLVGLFLLALSFSLLLVPFSIYKDADKQWRNPSIIAMFVCGGVILGMFLAWEILLASHPVMNKRVWYNRTFLLAVTIDIFYFMGGNARSTYYGSFVLVGTNLSTANWGYVVNALATCALSVFGLAAGFYLRIFHRYKFLQIGGLVIRIVAMGLYLYGRNGNLTTMVVAWSQILNSLGGACSVVGTRVASQASVPHQDLASIISQLALWTRLGGAIGSAIAAGIWTGTLPDYLAATNLTPAQQSRAYNSPTTIKTSYPWNTPLRNQINQAFSKTMKPIFIVALVLAFIPLFAGLLMPNYYLGKTQNAVDGTDNSGRVIESAEDNPNAEINRKNVKYAKGTRLSWLW