lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.
Subcellular Localization:
Nucleus.
Sequence:
MSAQGEGGGAGGSGGGGAGSDGGGNAGQSSTGSGTVAVTNGGNSSAKNQLPLTPRFTAEEKEVLYTLFHLHEEVIDIKHRKKQRNKYSVRETWDKIVKDFNSHPHVSAMRNIKQIQKFWLNSRLRKQYPYRDGSSSNLSSGSAKISSVSVSVASAVPQQQQQQHHQQHDSVKVEPEYQISPDASEHNPQADTFDEIEMDANDVSEIDEDPMEQQQQQQQEAQAQAQAQAQAQAQVQSAAAEMQKMQQVNAVAAAAAANATMINTHQINVDQISAEKLTLNDLLHFKTARPREEIILIKHPEATATQIHTIPTQAQQHPMATITAGGYNQQIISEIKPQQITLAQYQAQQQQQAQAQAQAQAQAQAQAQAQAQAQAQAQQLAQQQLAAAQHQQLAAAVQVHHQQQQQQQAAVAVQQQQAAAAAAVKMQLTAATPTFTFSALPTVTAATTVPAAVPVPVATASSGSANSVAVNTSTASSVSINNTSLGGGGGNGATNSSATAADSFEERMNYFKIREAELRCKEQQLATEAKRIELNKAQDELKYMKEVHRLRVEELTMKIRILQKEEEQLRKCSTS
The following text describes a protein:
Function:
Glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where its binding to self markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop. As a cofactor of the serine protease factor I, CFH also regulates proteolytic degradation of already-deposited C3b. In addition, mediates several cellular responses through interaction with specific receptors. For example, interacts with CR3/ITGAM receptor and thereby mediates the adhesion of human neutrophils to different pathogens. In turn, these pathogens are phagocytosed and destroyed.
Subcellular Localization:
Secreted.
Domain:
Sushi 1-3 domain represents the minimal unit capable of cofactor activity. The property to discriminate self surfaces from non-self surfaces depends on the C-terminal region made of Sushis 19-20.
Sequence:
MRFPAKIVWLVLWTVCVAEDCKEPPPRKETEILSGSWTEQTYQEGTQATYKCRPGYRTLGSIVMMCRGGKWVSLHPSRICRKKPCAHPGDTPFGSFHLAEGTQFEYGAKVVYTCDEGYQMVGEMNFRECDTNGWTNDIPICEVVKCLPVTEPENGKIFSDALEPDQEYTYGQVVQFECNSGYMLDGPKQIHCSAGGVWSAETPKCVEIFCKTPVILNGQAVLPKATYKANERVQYRCAAGFEYGQRGDTICTKSGWTPAPTCIEITCDPPRIPNGVYRPELSKYRGQDKITYECKKGFFPEIRGTDATCTRDGWVPVPRCAWKPCSYPVIKHGRLYYSYRGYFPARVNQQFVYSCDHHFVPPSQRSWDHLTCTAEGWSPEEPCLRQCIFNYLENGHTPYREEKYLQGETVRVRCYEGYSLQNDQNTMTCTESGWSPPPRCIRVKTCSKSNIRIENGFLSESTFTYPLNKQTEYKCKPGYVTADGKTSGLITCLKNGWSAQPVCIKSCDRPVFEKARVKSDGTWFRLNDRLDYECVDGYENRDGRTTGSIVCGQDGWSDKAACYERECSIPEMDPYLNAYPRKETYKVGDVLKFSCSQGRIMVGADSVQCYHFGWSPKLPTCKVKKVKSCALPPELPNGKRKEIHKEEYAHNEVVEYACNPRFLMKGSHKIQCVDGEWTALPVCIEEERTCGNIPDLDHGDVKPSVPPYHHGDSVEFSCREAFTMIGPRFITCISGEWTQPPQCIATDELRKCKGSTLFPPEGRQAHKIEYDHNTNKSYQCRGKSEHKHSICINGEWDPKVDCNEEAKIQLCPPPPQVPNACDMTTTVNYQDGEKISILCKENYLIQDAEEIVCKDGRWQSIPRCIEKIGCSQPPQIDHGTISSSSSAEERREIHEQRLYAHGTKLSYTCEEGFEISENNVIICHMGKWSSPPQCVGLPCGLPPYVQNGVVSHKKDRYQYGEEVTYDCDEGFGTDGPASIRCLGGEWSRPQDCISTNCVNLPTFEDAVLTDREKDFYRSGEQVAFKCLSYYQLDGSNTIQCIKSKWIGRPACRDVSCGNPPQVENAIIHNQKSKYQSEERARYECIGNYDLFGEMEVVCLNGTWTEPPQCKDSQGKCGPPPPIDNGDITSLLQSVYPPGMIVEYRCQAYYELRGNKNVVCRNGEWSQLPKCLEACVISEETMRKHHIQLRWKHDKKIYSKTEDTIEFMCQHGYRQLTPKHTFRATCREGKVVYPRCG
The following text describes a protein:
Function:
[U10-myrmicitoxin-Tb1a]: In vivo, this neurotoxin paralyzes about 40% of blowflies (L.caesar) one hour after intrathoracic injection, when tested at high doses (28 nmol/g).
Subcellular Localization:
Secreted.
Sequence:
MRVSYLSLTLTIVVVIAIIYAPETEAKAWADADAEAGLGFLAKIMGKVGMRMIKKLVPEAAKVAVDQLSQQQ
The following text describes a protein:
Function:
May play a role in ribosome biogenesis.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MVPRASTRAQGKPYDRPAASTKSKGKGKAPVHDLGAPSTHSQPSRKGKKAWRKNIDITHEEEALEKAREDERVTGGPMATKSNNELFTVDVVGDAQVGAKAKRQHKPLRSLAILSERSAVPSLTSRVSKAAPQKKKPLLSSAEKERLKRIARKTQAFSDGTGLASADIQARGPVEKDVWEEEQEFEVEGGFGEETIVKKKVKVPVTIARQRAAYLGSVDKAVETPEGGVSYNPSAESHAKLIDEAYKEELAAVEREKEEAALIEKFGSVVEARRHIKRSEFAEDMLVGDGESDDEESSGDQDLPEKKASKRKTTAQRNRQARQRAIEEAARQEKEKRKLANSVSSLAAFKKEVERKQKEQAEKERIAKLAKKEKERRGKQEGEKVGKYRVQKKRVEVQLGEDLAESLRQVKPEGNLFKDRFLALQKRALVEPRVPQLPKKKALKIKEFEKHAWKRFL
The following text describes a protein:
Function:
Mitochondrial cardiolipin-specific phospholipase which deacylates de novo synthesized cardiolipin (CL). Part of the remodeling process of cardiolipin, which involves deacylation-reacylation of premature cardiolipin. Has a strong substrate preference for palmitic acid residues and generates monolysocardiolipin (MLCL) for TAZ1-dependent reacylation with unsaturated fatty acids. The hydrolytic selectivity of the enzyme toward C16-CL substrates contributes to the preservation of C18:1-containing CL species. Has high specificity towards peroxidized cardiolipids CL(OX). Required to mitigate oxidative stress by removing CL(OX).
Subcellular Localization:
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Domain:
The HXXXXD motif is essential for acyltransferase activity.
Sequence:
MFKSTLNSIIRRPLKGFQLLRGADSSNTRPQSPRASARDVTEKQILRTPSAPTAIPLREIIYRVPSLFPRPLEDSVKDFRDFIKNEDAFQTELLKTLPFYPTPSESKTARLIRTVVDDEGNYINEFCIRPRKTSVPEADLKHLVFIHGYGAGLGFFIKNFEDIPLLDNEWCIHAIDLPGYGFSSRPKFPFEYPRDNIHSVQDWFHERIHTWFSKRNLLNRPEKNIVMAHSLGSYLMALYLQKYKESPSFKKLILCSPAGVSYRDFNNTASEVEKWKPPPWWYVKLWDRNISPFTLVRNFRQLGSKITSGWSYRRFKHILNGDPEQSKRFEALHRYAYAIFNKRGSGEYLLSFALKCGGEPRLSLEQQLFDGKKSDILKNSNCDWLWLYGDDDWMDVNGGLRVSRFLKEKLKQKSNVIIVPHSGHHLYLDNYKFFNNILTKEMQKI
The following text describes a protein:
Function:
Lectin component of the HRD1 complex, which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). Specifically recognizes and binds improperly folded glycoproteins as well as hyperglycosylated proteins, retain them in the ER, and transfers them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 as well as hyperglycosylated HSP90B1.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MDTSSLLNVNNRLLKIWNGKMDAIYLSKHDKDTENKENIILSSKFGQQYQCQFDSYNEISEKVREDGVSNSKLLISDLLKPLEDKPCLILTTGWWTYEFCYKKQIKQYHISDKKISGDIIILGHYSEDFNWSDAQSAQAPEATMHYHSQQYVNGTVCDLTKSLRRTEIRFRCKEGLQDTLDGVEEPLTCTYILHVSTNLVCRHPLLRTTTNKNLLPIICNPVLNELEYREYLEVQKQLEELEAEESKEKLKKLEGRDLERYGAEALNRFGVIEVDGASIKFFVLSTDGFQNFDDTLNDGSKDGDEKSEASSSADSKEPIDPTQQQQQTQQSLIDRKKSAVWKLKEMMSKEFQGTFGKREIITKKVNKVARDEIRSNGDSEGDEQVVPATADADDKDDDTIVAATGEDKLHDDVVKGEIITKKVNKVARDEIRSNGDSEGDEQVVPATADADDKDDDTIVAATGEDRVDGKKDVDKVSDAGKKFANGDDDDDDSMITWQGYGNKEIKFKNTKINIKAVDRQVRDLMKKKNAAAADDENVGGGVPAGGDEKDAEARYKQSMSKINDGSAADKTDSVDKAGNGYVIAVDSNEDDVKSKATVKTVEDETDDAVENKLEAFMNDISNYLNEQLTSVQNMMDVADDEVASQINELLKVRGDGEVGEGSDVDKKVTSSQVKVDSAAAADDKGDDKSDDGDEKSKSTSRKLSHIHKLKAKLSQLSKRIFNYLNGDDDDQDADGLTKLVEDTKLSFSLSDSNSDGDDGDGVGGNEKKVDNKAYDEKVVGDSRVEEDGLKKVHSRDNVAVEGASAENVGSGGGVTKDAVVEDVDTEAARNDDEDKSADASKKLKTSIFGSGGQMTDREKSLRHMILTIMKQNEQNTRDGQRHGKIEENYAFDWKERKKKLNLKKDEL
The following text describes a protein:
Function:
Involved in the activation and reutilization of phytol from chlorophyll degradation in plant metabolism, including tocopherol biosynthesis. Catalyzes the conversion of phytol to phytol monophosphate (PMP) (By similarity).
Subcellular Localization:
Plastid, chloroplast membrane; Multi-pass membrane protein.
Sequence:
MVSLISAHLLSLPSSAPRSRPQSRPPLSPPAAAAAASCSFDLPRPRRLVADGSRRKGTMAAAIPPEASGLAHDLGSAAVTAGVALALLRFFEELAKRGVFEQKLNRKLVHITIGMVFLLFWPLFSSGSYAPFLAAVAPGINIIRMLLLGLGVMKNEAMVKSMSRSGDPRELLKGPLYYATTITFATSIFWRTSPIAIALICNLCAGDGIADIVGRRLGQEKLPYNPNKSYAGSIAMALAGFMASIGYMHYFQSFGFIEESWSLAFGFLVVSVTAALVESHPISTHLDDNLTVPLTSFLVGSLVF
The following text describes a protein:
Function:
Possesses chaperone activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MSLIPSFFGNNRRINNNIFDPFSLDVWDPFKELQFPSSSSSAIANARVDWKETAEAHVFKADLPGMKKEEVKVEIEDDSVLKISGERHVEKEEKQDTWHRVERSSGGFSRKFRLPENVKMDQVKASMENGVLTVTVPKVETNKKKAQVKSIDISG
The following text describes a protein:
Function:
Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TGF-beta. Acts as an adapter that mediates the specific recognition of LIMK1 by CDC42BPA and CDC42BPB in the lamellipodia. LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation.
Subcellular Localization:
[Isoform 3]: Cytoplasm. Cell projection, lamellipodium. Note=Co-localizes with CDC42BPA, CDC42BPB and LIMK1 in the lamellipodium.
Sequence:
MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAARAPDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMVGLRQLDMSLLCQLWGLYESIQDYKHLCQDLSFCQDLSSSLHSDSSYPPDAGLSDDEEPPDASLPPDPPPLTVPQTHNARDQWLQDAFHISL
The following text describes a protein:
Function:
Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
Subcellular Localization:
Endomembrane system. Membrane; Multi-pass membrane protein.
Sequence:
MLVEKPNNQISIIIPTYNESQNILNILKSIKENLPKNISAQAIVVDDNSPDGTGKIVDDYLKNLKKITNYTIEVIHRKTKDGLGSAILKGIQQATGDTIVVMDSDFSHPPQIIPKLVESIKKYQYDIAVASRYIKGGKIENWSAKRKLISKFATLIAKKGLGINTKDPMSGFFAFKKNILNGLNIDAIGYKILLEILVKTKNVSITEIPYTFQDRELGSSKLSMKTVFDYYKSVWKLYRYGKPEEEKEKRKSVKFLYKAARFYTVGASGFVVNYLISLLFAGGISDMWYLHANVIGIIASISTNFILNKAWTFGDRDFRIKKTMSQYGKFALFSSLGALVQLGMVYFLVDSAEISYPLALILAVATAAFGNFVLNKKFTFKEKLLN
The following text describes a protein:
Function:
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MLLLLEREHPAVHAAVERILRGDSKIPVSVVRDFDGCEYHIRVEWDKEEKEMSQTSGVDSKDTGSGEVGTVNVGGTASVTVSLRSFTPFAELNTHGNFYEVLTTLFPSELQKFVVCDTHKGDGEDFTVAVHIPSNVPAKMLKEAMHSTAQLRAWSFVPAFARQFELFLTNPEVVQPLQLHYHDGEEMVVYNNRGSFIVAIALRVPSKDDAVLTRHFLQAMVEVRKHERSFCGSSAFIFEQGGPPDSVVAVTGPRGRVRDPNTFWCSFQLYKQQMEPPPRLVETVMHLVNFRTTLAYHIRAGRTYMHGIMRKRVESSLQWLNKAKARVAEETKITIT
The following text describes a protein:
Function:
ppGpp hydrolyzing enzyme involved in starvation response.
Sequence:
MRLKKQELINSLIIYYLKMNLDFDFFLSVLEFATHKHRFQLRKDGTAYIEHPIKVCKILKDAGINDIEILSGALLHDTVEDTDTTFEELEEHFGKQITQYVREATDDKKLDKVTRKKLQIEHSKTISYGGKMIKYADKIHNMGSIISTVPCPFKPYEVAQGYMVWGKKVCEAFRGINGVLDSQFDEILKGHITDNNGKTYPALPEGNLDEFLSHYYDLIHDQK
The following text describes a protein:
Function:
Functions as a two-component phosphorelay mediator between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction; Functions as a two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.
Subcellular Localization:
Cytoplasm, cytosol. Nucleus.
Domain:
Histidine-containing phosphotransfer domain (HPt) contains an active histidine that mediates the phosphotransfer.
Sequence:
MDSETLLWDLLGPILTHHDEGLAEVRVGYLDEQFRQVEDLQDEASPNFVEEVVVLFFKDSAKLMSNLEQALEKYPRDFNRWDAYMQQLKGSCSSIGASRMKIECLSFRDNCGQGNVEGCMGSLQKLKREHALLRQKLESYFQLLRQAGPAGAATRPVM
The following text describes a protein:
Function:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNLLPQLESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIVQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA
The following text describes a protein:
Function:
Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MQVLLNAFKRHELSEVVDVELSRDEDSVTSLAAAQSNDTSIVTFVGINSSLALQKENKNRHLRSFKIDYPPRRTNSASAEFKSPNGSTPGQTVKLSEESVFRTVAGSKGSTETYQRITRLSPWKGEGATRVAAIATGLASSGEIVFFNANTTKPSEGDVIGRIRLKSDEEAEDIDIAGQDEEKGLFPVAYTNGVDVFTCRISPETRSNAAPDVRCVYSPPANTNGKGPRPKFRALRFLSPTTLLLLQNAPNRKGCELIILDLRPTTSSSQATIIRRYKLRKSINIGLSLDVCNLGTSSSIKQQSIIAVSGSDQSLEILTIDVDSSRQYRAAAGYSQIRRYATIRDVHPFSMTRICFSHFVPPPAPVTPETPPQYIKLASVSLGNTVVVHTFPLSPTPPSSRNPRYVLVRPGESELLTGFSSTLAAVLSIVLVIFLLQAFTEIRGVMPPYLGITDYLPTDIRTKIAVPYNAPLPHFPSSPTPILQTQAFPSTSAAPDEAQSRTLRDIIQDSEASILISCDPLNSKIIVEPHNPHPSSTTPEPDLDAEVTPESDLTTRPAQQWTDLSVEDRQTWKTYLINAGFLDQQQDEDESILSRVFFRDSCPRRQPSSNDDHDYTSVDSADK
The following text describes a protein:
Function:
Probable polyketide synthase.
Sequence:
MSLSTLSPVLSLLSSGSNEDNQNPRTGVFLAISIISLIIYAALSIICKVKFYRGTVIFFYNPITHKYLNYEVFITFGYFIPDIIPTLIQISIIHSNMKNEQEDQTYINMLYEEENDNEDYNGMGNYALNESYYGASQDYSDQNNNSGGGNNEIQTIGGDGYSYYNSPSRNGSNSSFDSPSFVYSPSAKNIWESLEDAHIDPIKLRGTNTSVYVGLSTNDYQNNLKNSEEVLQNIFGSHNHAASNRISYCYDFRGQSMSIDTACSSSSTAIALGYQSIIEGRSNYSIVAGTNLLLDETFPKAYTYLNMLSKNGRCKVFSADADGFGRCEGVCVAVLKNLEQAINDGDRVYCVINGVNSNADGNCDKNNFYSPSKTSQYDNIKEMFRLCSSQVTESDVDFVECHGTGTPTGDPIEVEAISMAFKQYHNQQNPLLIGSLKSNIGHVECCSGIASLIKCCLMFKHRQFAPNINFNIPNPAIKFDEWNLKVITEVEPFPSNKKVSMVINNFGITGSNVCMVLSELSRESESTYYQYEENKQYLVPFSANSKQSLNLYISSIQNDINNLSRNCEFFDFVQYQIFSKSTKLYQRSVALANKWSSLKNTDSFIKTNNSITSNLKLSEKENIDTNICFIFSGQGTQWNGMGEQLYTNDSYFKSTIDLIDSKLNKYYGYSILERLRSTNDETIHHPIIAQPSICMIQIALFETLTKQWNINPDYIIGHSLGELTSQYFSGSIDLDTFCYILYHRSIAQQKTIGSGRMLSINISSDQFNDQFSTEYPTIEIAFITQQIQFQDKVKKDLIDLKFESFKPKIPVLSTIYQDFFNGQDNKFNSEYCFRNIREPVYFTQTIQKLYQHIESNQSCKNLIFIELSPHSALAYHIKQIQPPSTQSIQSTVLTTLNKTKGDINQISQLISTLYCSHNYPINFTNQLKTIDKDNQTSLQYKHKDLNLPRYQWDDKIFWREDSKQKQYRLHGPAIEILGNKNTTSPFITYNTTIDVEKPQFQYLKGHQVKGKYYFPGSGYIENIINSFPNEDLIISHLEFKVPLIFIEGVNKQLQTNIYQTSKKDYRAQFHYYEPNTNKWILSSCGNFQTFRFTNANEKKLDIEHLKSKCKFTMLNSQTFYDHIKVKTGIVYTGFFKSVKQSFIGDNCILNQVKFNHIHNNVKTIIDCATLDCCIHSPLCLIEENTQLVFDRVDNIQFYSSNLPKNYSSDLFVFSKYHGKKGDSFEFSTTIMLNDGTVIFEIEKITMTSTIQVMDPLKIQYPQEEFQTTFLQLKDCEAVTNIELFNHQQNNTEWDKENYSKFIPSIIYFYIKNKIPDLKIEDIKHNTIQMLRDRYLMNQKHSRLFNFVFETIKEYYQQEYIESEWNEDKLVFCNIITKSTKIMVDLLFPFGDKDLLETPSSLYDNGLLEEFYLHPYYTRNQKILSDILIDSLNPLTKKKNVIRIIEFGGGTASLSFEILNKINQLLKSKESNDIEIEIEIEYTFSDVSQTFIPSAKEKLSSFGIDNVSVLFKTLDLENNLISNQQLKPNYYDFVVMSNVIHVVKKISFGLNEIHQILKHNGYLLFIEPCYKSLVGDSIFGVFDQWWSFEDTEIRTDRCSMTEDQWYKVLSENNFKNINVSESNGISNILIHSQKQESQSFINTNNSNIIVYSDINNNNNQSFINNLLKDQKNQVVINTIEQFNNISKDINQNTIIYFTKTINQLNTNNFKQISLEYIQIVQYLLKNKLTSTKLVLLSKNCYYKESSNYLASSVTGSFRFFLDQLDTLLLFSIDFDDKSLMNISNNQLINQLIDTNNTEREFIIRENKVYIERIKFETNIFNKYTSNSIEKLNGNNKDNLYSILNENLEFQLESKKQLGEDQIEVQVQAIGINYKDYLAYTRNLPAELINHNSDIHSPEFGAECSGIVKSVGKNVDNFKVGDHVYTLNNRTSSSTIILNKNQICHKPNNITFVEAASVPGVYTTSFYSIFKIGKLDIEDQESILIHSATGGVGLSAIELLKWKGFKSHLFVTVGSEEKEKYLKDRYGSLITGIYSTRNKDYVQQIKQKLKELGSNKQGVDVILNTLPAEYLESNFRCLNKGGRIVDLSITHLNPNEFIDFNKFKYNYTYSNVELLLLDFEYINEILKKISEGISNGSLSLIPITEYSVLNIKEAFEYINQRKHIGKIVVNYDKDISDHLLQNKYEGTKETNQPIIKSNYTISSELGKTILITGQSGIALEIIKWISKYSKSVENIIILSKSTLKWELELLMNKSKSNSNKSINYYFKSVDVEYQDQIETAINNIFNEHPSINNIDSIFHYAFVHDICEPINIDTESINRSHGAKTIGAINLHELSLKYKWNVNNFILASSISSLFGIMNQCTYVSANCVLDSLAKHRKSLGLSALSVNWGNIGTSGIVARIESIGQLLDGIGLEPIPTNILLGGLDLLLQNKQKLHEDYNNIIINRTNFENIQFSHLYTHKFGFKINSLNDKKISTKVNKNEEHIDEFQNAVLSKLADLLSINESNINTNTILSDYGFDSLLVVQVKNWLDKKFKKNLFNISDLQKLSINDIIKKLISQ
The following text describes a protein:
Function:
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MVSSSSSPTVSSRARILLSLLKTNPFRKLETDDLNANPPTFSVFCGGTELYSFPASQSDATERVQENVRHFIGNYISVFVVIFLISLYKQPIAFLTLLASFPVKDYLDHLITKRGLDQTYPFIRRLLLFISKAGW
The following text describes a protein:
Function:
Component of a histone deacetylase complex responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Has a role in silencing of mating type genes.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MADDTAYILSEYLQTLDNVPNETKHIFDEISVKEVAVHDIWKRIQAADSQIQSYIKSHGSLTPHPKEDALYSTIREEYQKAINIQNEKVQLADRARLGLTRHIKRLDDRLAKAGHGFTAAELLNAPDYYASSPYGGYSPSGASSARQTPAPSRSGASTAGRRRTSATTRGAIQNGVYHSPYTASLADSGSTRGQKVSNATATTQLETKADSTTPNEMVSEEDMEEDNEKYCFCQQGSYGQMVACDNANCEREWFHMECVGLKAPPEGTWYCEACRDQKLVDAK
The following text describes a protein:
Function:
Essential for the maintenance of cell size and integrity in response to osmotic stress.
Subcellular Localization:
Cytoplasm.
Sequence:
MGNNPSKSKGGLQSYPSFSRSDTQGSTRSGRSIRSRLSSMSNNSEASYKTAGGETEPQNVPGAPTSTQDPGNVSTEHITPVDNATLPPSMQQIEPKDPILVRADGSSGSAHDTNDAHSQPVTPAAVPSAGSSPKDGTPGPLSADVPGGSGSDYFARRQLFSPPPGTPATPGNDSFNNSGASTPNIISENNMTLNIDEVIQRLLDAGYSGKITKAVCLKNSEIALICRRARSILLSQPTLLELLPPVKIVGDVHGQFGDLIRMFDMCGFPPAANYLFLGDYVDRGKQSLETILLLLCYKIKYPENFFILRGNHECAKVTRVYGFYDECKRRCNIKTWKTFVDTFNTLPIAAVVAQKIFCVHGGLSPSLSSMSEIRSIVRPTDVPDYGLINDLLWSDPADTQNEWEDNERGVSYCFSKVAINKFLTKFSFDLVCRAHMVVEDGYEFFNDRSLVTVFSAPNYCGEFDNWGAVMSVSEELLCSFELLKPLDSAALKQEMKKGKHQRRLSLETRSAPATPQSV
The following text describes a protein:
Function:
Required for normal heme biosynthesis.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MQKDSGPLVPLHYYGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGTSLLMVAKLGLSMLSSSHP
The following text describes a protein:
Function:
Involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
Subcellular Localization:
Nucleus.
Sequence:
MNLCLIDPFKQSDVPETVEYYLVDPKNIKSNCASFNRRGTLLAVGCASPIGKILVWDFDTKKIVRTLYHHTGCVNSISWSRNGKKLLTASNDGSLVLWDLATSKILYSLELESPILFAEFHPRNNDLCLIVLQKGTDPILLNFKSSEKTPLNIKSLVTSYIKREENSTGVIPTSVNSNYNGVATFASFNRRGEKIFFGDSCGMISVLDFKSMTIDRQFKVASSNTTVKQIEFSRNHRFMLVSSSDKVLRLISLESTNLYQQMREYQDSVNRMHWKKCCFSSNNEYVVGGMNHKSIHSIFIWSVSGSLVKDLEGPKEGLVDVVWHPLRPIIVSISFTGVIYVWTAYFEENWSSFAPDFQELEENLDYVEDEDEFDAKDSDNENQEVNNNNNNNIGRNPYKKIKTQQELNDKNSEEEEFVDVDHNDRITEFSSDEEEDLFCFSAIDDRYVSNVKFDDPRHPLYEKYQKDKEDSSSTTSNSTISSSSSPSPSSSSTTTTTTTSQKKDETQKKEKSTKKERNSDSKKRK
The following text describes a protein:
Function:
Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSNGRAVNGFLLDITGVLYNSIYKSDGVAVPKSAEAVNFLYQHSKVKFLSNAKGNSNRNVARRLQRLGINVREEDVITPAPVVAQYCRENKLRPHLFVRDDVLEYFDGIDTSSPNCVVMGEVEEGFSFDRINRAFRILIDMPKPLLITMGNGKFFQRVDGPCIDVGAFAAALKFSTNCEVLNIGKPSRFYFEQGMNALGMKPEEIVMVGDDLMSDVGGAQACGMRGVQVRTGKWRPDFEKMPVTPDLTADCLYDAVKLIADNGFRL
The following text describes a protein:
Function:
Transcription factor probably involved in vascular development and shoot tissue organization. Binds to the DNA sequence 5'-CCGAGTGTGCCCCTGG-3' present in the promoter region Box II of the phloem-specific rice tungro bacilliform virus (RTBV) promoter. May regulate tissue-specific expression of the RTBV promoter and virus replication.
Subcellular Localization:
Nucleus.
Sequence:
MDKDKSPAPGGGGGGGSGRGLPPHLPRYSPFGSPSSSFSFMGDLSASSSSQPSSNSGHFAYETPSDARRFSYDVSRMPDFPQRNAGHRRAHSEILGLPDDICFDSDLGVVGSHGGPSLSDEAEEDLVSMYIDVEKFSSGATSAALSIGEVSQSALPPVQAPLQGENVASSSSEKPRIRHQHSQSLDGSTAIKSEFLLSGGEGPLSAEAKKAMSAAKLAELALVDPKRTKRILANRQSAARSKERKMRYIAELERKVQTLQTEATTLSAQLTMLQRDTNGLTAENNELKLRLQTMEQQVHLQDALNEALREEVQHLKLATGQMLPNGGQSTNTIPPSLGANHQFYHQNQAMHSLLAAHQFQQLQIHSQHPQQLQPSHQIQPPSSLQHLHTLQPQQQPPADLRMKGSSTSQNQRGEATSDNNSAQE
The following text describes a protein:
Function:
Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MASIVYDGVGGGEALFEGMKFFILQRVPMRSRWIELIQSNGGEVTKFEKKAQIIIADGARKDAPPGSVSWKFIEESAKAGKLVDMEAYRCGAQAGTISERATAQPAKTSRTPYTAEDDRILTKWVLKAERMGRSTKGNQIYMELAARYPHHTYQSWLDHWKRYLLPRHEAGKLHYDIEDGDSPSPERQPKSAKREPAKPPPTRIPHERVQPCAPKERVPVPDPSSLQRHSSSQSSRPAFSKASFPEGDTRKPVDRRPFTKEDDDLLRKEFVGICKLDPSKEIAAWEACNRAHPDHTAQEWRNYFHEEFFPREMKEREMKKQAKIKPVPSTTSRHVSNPSQDEVHKASTRTKHSTNDPEKASVKAAVKSPVIPSQNFRSRAHQEPKSTPEVISGKVDLEQRPYTNSLLKEEAYFTHTLKEFSEALGFEPDDLNFYPVVCGKEISIFKLWQIVMLFGGFAKTNADSRWQEVADRLSFPIVNRAKAAKDLKSCYEEILSELETAVDEAQNDTENPEFTTSQEEVMIASQLEATILRSVQRSSDHEDGIEDNDEVSKLPPPRTKPKQQFTTPTKKRTIDSDGLSNRTGSSVTKHEIKRRKVQKGKGKEVEIPSTPEHIFNATQPPISHHTAPPKYPFDENSEDDDREARERIRRIQKRKPEGSSGKPSAKDPLLEPETQDFHYPDIGKEASIASPTPAPKNRAAKDIIDLTQDSTTESETEPEPEPDSESDSEDSINAEFAKYLDLGYSREIIAEALIASTYVYDVASVIMEQLKMGHDIPDNMEGAWTKRDDDALLKGTGPEYERIREKHGDARIAARKKFNRHIQSLQELD
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Sequence:
MASSNKKQSSILSFFKSNEEKTNKSSCLNEINNKVGDGKGHKQNEINNNVPEKRKSGDDKSGVDSKNKNEKENLGSNKKINMLDMFLSKGEMYNKPKIIDNINKEPINGDMLSTDKNMNVNKTNKMHNLFLDEEKTDMSKTKCSNDDVYDNNVYNNNVYDNNVHNNNVHNNNVRNNNVHNNNIHNNNNYGNIYRNDNCVVKSNECNNNGVELDEDSNYQNMVHNQMLEGRNYMDNLESSTEDDIIIKKKRKIILDSVSDKECSDAKENNINKNNCSVDNKLTNLLYEPNKEIDDNLLLLDDNNNNNIKKCIEKRKGDDSKKSQELDGLRNKYLNLPISITNDKFRLYIEHYFLYCNTFEFPKWIQPQYIRDINLRTPDHADYDSSTIWTPPPDHKWAIEYKQAHYTPGMQQFWKIKSRNFDKIIFFKMGRFYEIFYIDACLMHTICSLNWMSGEHKPHLGFPEQSLHFYAKKVINSGHKVVVIEQMETPKELEQRNKESIGPKDKAIKREINEIYTKGTILHDNMLSAETKYLVCFYFDEIENMTNVNNNIKDNDDDHNNIKDNDDDHNNIKDNNDDHNNIKDNNNYTFSQYDNKNKCNFGFVVSDIATSYIAVGYCNDDESRIVLRTILAQLCPAEILYSSKNINKEVLSIFKNIPTSPELTCLNSFPNIISSFDEINKYFENMPSNLEIYKEQTSVICAFGGFIVYLRSLLLDKKIFRFCKIEKYDLFKRETYMVLDATALKHLEILETQSGDTKNSLYDYVNKTCTNFGARNLRRWICSPLLDCEKIRERLDVVDFLKNNEQILSLIRMKLKKLPDIERLLNKICIQASQSERGAVFFDNVVNTKLKEFVTFLNAFKEIDTMLIDVNRIERDGELPSRLFQICNTPDICKDNIKGSYPNIGLITNEFLEKIYFDGDKEYKPAEGCDEDIDKINEKEKNVENKLNNVLEHMRTQLKIPTLKFVHAKFKYEVECPDNIPKSFLKNVEITSAKKGYVRIHNDEIKSLVEKLEDIEQEKKDAIYPFFQKLFHLFYAHYEKYVSACRLVAELDCLQSFAYVVLNTAFPLTRPILHPMDSKQGEEKTPFLILEDNIHPVVAMLMPNFISNNIYMGCDKEKQSTLLLTGPNMGGKSTLLRQTAISVILAQIGAFVPCTYCELTVVDKIFTRLGSSDNLFEGKSTFLVELEDISNLLKQSTKYSLAILDELGRGTSSFDGTAIALSTLEQISDVIKCRCIFSTHYHLLVEEVKHNKNISNYHMSLSIDDEQEKIIFLYKFIKGVCPKSFGIHIAKLAGLPKEIIDLAHEKSLLFENVTDEFCKIIKYKNITRSLLNEEADEKLVTLFHKYKKEFA
The following text describes a protein:
Function:
Replication termination factor which is a component of the elongating replisome. Interacts with nascent DNA.
Subcellular Localization:
Chromosome. Note=Localizes at the replication fork.
Sequence:
MGLDGGTIPTRCELVKTKKKEVKVFDKDQVDFGKWFLCALAQDTLSEPIVLDDLGNLFNKDNIIEALLNGSLETSKNFSHIRSLRSIYTVNFSPNPAHEKDSTVSPWLCPITKIEVGSSNYKFKFLKTCGHVFSEKAFKELKNDDSNNNNNNNNNNKKEIDSSKDNLSCFLCSKEYITNDLITINPSGEEFEQMKVTLQEKLANSKKKSSKKSDKKPDNKKRSLESNLASESSFTSNTLAQTNEEISKKMKSEAFSSIFKSNSNNDTTKTPNK