lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3 (By similarity). Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (By similarity). In association with ASH2L and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPPDAVPSSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSTKGKVQAELSQSLAAGGAISELL
The following text describes a protein:
Function:
In conjunction with KorA, inhibits the transcription of the kilA, trfA and korAB operons. Is also involved in the negative control of the kilB operon.
Sequence:
MTAAQAKTTKKNTAAAAQEAAGAAQPSGLGLDSIGDLSSLLDAPAASQGGSGPIELDLDLIDEDPHQPRTADNPGFSPESIAEIGATIKERGVKSPISVRENQEQPGRYIINHGARRYRGSKWAGKKSIPAFIDNDYNEADQVIENLQRNELTPREIADFIGRELAKGKKKGDIAKEIGKSPAFITQHVTLLDLPEKIADAFNTGRVRDVTVVNELVTAFKKRPEEVEAWLDDDTQEITRGTVKLLREFLDEKGRDPNTVDAFNGQTDAERDAEAGDGQDGEDGDQDGKDAKEKGAKEPDPDKLKKAIVQVEHDERPARLILNRRPPAEGYAWLKYEDDGQEFEANLADVKLVALIEG
The following text describes a protein:
Function:
Calcium-binding protein involved in larval development and metamorphosis. Likely to function as calcium buffers mediating the transport of calcium from the sea water to the blastocoel where calcium is required for skeleton formation.
Sequence:
MAAKIIFTEQQIAEFKKKFEALDKKSDGTFPTRHLKYAMESVGHVLTEDELDKSRADDGTMTFPEFLEIIAGKVRSNWRTAMPQYRTAFKALDKDGDNLLCADELRQAMLSIDRPMSEEEINAMIDKADFTNDGKVDFKEFIKMMMNFC
The following text describes a protein:
Function:
Involved in the mitochondrial expression of subunits 6 and 8 of the F0-F1 ATP synthase.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MIASRYVASELESVTRKLELQLYERAAISEVLEQTSTDLELAKANEVLQTIKEEADACVAAINGGQKFYTIKYDQILSGLESLSGGQWSVGSPLEPLIRDGISDYLHILLYYALLSKNLAKLPQLLLDQEYYGHVSRCSWFMRLFYGLQIMPVKLIEFFRGHALQELPSKLRQTLRIHNFQLVGLPTQRAWQWTKLPIAMVDTDIIQKTASLDSQLDINVKKFGKLLREFPRQKSDRLEVLSDFLDLKPGSSEFAVVRAVQKWNVDSCAPQPNWIVRYWPTILIALAGGPAGIAAIWNARNDIAAFIKHNLFEFARDLVKNWLVEPLRNIWSTVHHDPTSSIAIMSQGTLDTEINSLQRMLIDFLKEHEYANTVDTSVLMKEIEQGNLTQFMEIYEAQLRKPIRNLVTGDLIRSLLIQIQKGKVDGSLAIHGIDKLLQSQQLVFGIVSISPALLILYVLCNSLTKLVKYGTVWSKGAKYRRSVSVSLNNVERLLNSPIEEFDGDKGNWNLGLLTLEMANLREYGAKLVPHSRTAEWCRDIDEMASSSALSTTGKLNVINRIYHVYGKYF
The following text describes a protein:
Function:
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Subcellular Localization:
Endoplasmic reticulum lumen.
Sequence:
MFRLSIILSLLCVFPVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQIDEQQNDRGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQEDLHGATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSEWLLEARKRLHGKPLGFISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEEALKNKILYEGQLARERSFAPRKQVELPQIAEKEQKESYKLYTQVCRGELHQSPREQRNLRCWLYHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKVGQSENSTTSEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQSVFSWKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQGSKWICNEWFHVGAQEFRRPCGLSSDEGKFLHLKDI
The following text describes a protein:
Function:
Catalyzes the oxidative deamination of D-amino acids with broad substrate specificity.
Subcellular Localization:
Cytoplasm. Secreted, cell wall.
Sequence:
MCGMRGRVVARAVVVGCGVAGLSAAIALRERGFGVRVVAREPPERTTSAVAAAVWYPYRAYPEERVLSWGARTFEVFRGLAADPRTGVRLGEGVELLRRSAPGEPWWREAVSGFRRCREEELPPGCRGGYRFVAPVAEMPAYLAYLLDRLRGAGGTLELREVSSLEEAGEGADVVVNCSGVWARELARDPSVFPIRGQILRVANPGLERFVLDEENPAGLTYIVPRSGDCVLGGTAEEGRWSTEPDPATAEAILRRCSALEPRLRGARVLEHRAGLRPGRPEVRLELEELPGGTPCVHNYGHGGSGVTLSWGCAEEAAALAGAALS
The following text describes a protein:
Function:
Involved in the transposition of the insertion sequence IS3.
Sequence:
MTKTVSTSKKPRKQHSPEFRSEALKLAERIGVTAAARELSLYESQLYNWRSKQQNQQTSSERELEMSTEIARLKRQLAERDEELAILQKAATYFAKRLK
The following text describes a protein:
Function:
May play a role during embryogenesis.
Subcellular Localization:
Chromosome, centromere, kinetochore.
Sequence:
MSGCEEEAGDGYSSAEDEDYVPSGAEYSEEDESELLREEEEEAAGPRPTRSRNSPRQATRRKKKKRRGLVLEVDEKEEGKAQENEDEEDDLKQSEKDREEEEKKKEDALWASFLSDVGQKPKAAATQATHADKAGEVKSVNKLQGKPKESEKPKDSGKVTITKVFDFAGEEVRVTKEVDSSSKEAKSFLKQQEKWQSSAPGSLPTVSGSETQDQIRSHCTQLLVGAPPLFFHAAGIHHCLAVLHLLRTGDGNAAGVKRPSGISSLLGKIGSKKQKMSTLEKSKLDWENFKEEEGIVEELAIHNRGKDGYIERKAFLERVDHRQFEIERDIRLSRMKP
The following text describes a protein:
Function:
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
Sequence:
MKEEKKLLLREVEEKITASQGFILLRYLGFTAAHSRSFRNNLSGVSAEFEVLKKKIFFKALETSGVEMDPEGGEGHLGVVFAYGDPVSAAKQVLDFNKQHNDSLVFLAGRIDNASLSGREVEAVAKLPSMKELRQQVVGLIAAPMSQVAGIMNSVLSGVISCVDQKAEKTQE
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSELFGVLKSNAGRIILKDPSATSKDVKAYIDSVINTCKNGSITKKAELDEITVDGLDANQVWWQVKLVLDSIDGDLIQGIQELKDVVTPSHNLSDGSTLNSSSGEESELEEAESVFKEKQMLSADVSEIEEQSNDSLSENDEEPSMDDEKTSAEAAREEFAEEKRISSGQDERHSSPDPYGINDKFFDLEKFNRDTLAAEDSNEASEGSEDEDIDYFQDMPSDDEEEEAIYYEDFFDKPTKEPVKKHSDVKDPKEDEELDEEEHDSAMDKVKLDLFADEEDEPNAEGVGEASDKNLSSFEKQQIEIRKQIEQLENEAVAEKKWSLKGEVKAKDRPEDALLTEELEFDRTAKPVPVITSEVTESLEDMIRRRIQDSNFDDLQRRTLLDITRKSQRPQFELSDVKSSKSLAEIYEDDYTRAEDESALSEELQKAHSEISELYANLVYKLDVLSSVHFVPKPASTSLEIRVETPTISMEDAQPLYMSNASSLAPQEIYNVGKAEKDGEIRLKNGVAMSKEELTREDKNRLRRALKRKRSKANLPNVNKRSKRNDVVDTLSKAKNITVINQKGEKKDVSGKTKKSRSGPDSTNIKL
The following text describes a protein:
Function:
Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.
Sequence:
MRFSNAGGEKGSFDTGRNVRGFAVKFRTPKGNWDLTIRDPAKFPLLIQALSTNTQTGRHDPDATFDYLGSQCRGLCPNTSVFYPTLGLPKTDAFSGHVYKWVKQDGSWVYVKITFKSLQGNYNYTAAEQGSIQNPGQASQELFESIQAGERPGWKVYAQVMTPRDAEKFRYNVLDLTKEWREDLVPLNEIGKVELTQNPTNYFAEVEQAAFTPSNIIDGWEPSDDPVLQMRLFAYTDAQRYRLGANYQQIPVNCPLSAVANYQRDGASSYLGDQGNRPAFDASYAHLAVVPRAYNNDNHTIWKSGAIRYLSQIAPIDFEQPRYFYDNLSPEQKSNLVGNFAGGLSQVKNRNVVQRVLQVVQQASPELAQKIYFAMFASRKAN
The following text describes a protein:
Function:
Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to 5'-pGpG.
Domain:
The EAL domain contains a functional active site loop (loop 6), which plays crucial roles in stabilizing the overall protein structure and participating in catalysis, and also controls c-di-GMP and Mg(2+) ion binding.
Sequence:
MATPPYPEDEHSRQAYVDQLGLLEEGADEVFEEILAAATSYFQTPIALISILDHQRQWFRASIGLDIRQTPRRDSFCAYAILGKGVFEVADATLDPRFRDNPYVQGEPRIRFYAGAPLATAEGLNLGSLCVIDREPRGPLAERDVAMLEHFARLVMARIHTLRSTNYIDEPTGLYNRLRLQEDVSLRLQRDGALTVIAADLLPLALLNTIIRTLGYPFSNDLMLEARDRIRAELPDFTLYKISPTRFGLLLPRQQQEETESVCLRLLRAFESPVVCRGIPIKANVGLGVLPLADDTLDGDQDWLRLVVSAADDARDRGVGWARYNPPLDQAQQRAFTLLTSLSQAIGTEEGFHLVYQPKIDLPTGRCTGVEALLRWRHPQLGFVSPAEFVPLAEKTALMRPLSDWVLRHAMAQLAQWNARNIPLRLAINVSASDMEDSSFLEEAVRLAKTYDIDLSALELEFTESVLIRDASAVGSVLLRARELGMGIAVDDFGTGYSNWTYLRDLPITAIKLDQSFTRDLAGSPKAQSVTQAVIGLASQLGYRVVAEGIETHDTFHLLQAWGCHEGQGYLIAQPMLPEQLEDWLRR
The following text describes a protein:
Function:
Potential calcium-dependent cell-adhesion protein.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MNLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGSSTSLVYRLVSKAGDSPLVKVSSSTGEIFTTSTRIDREKLCAGSSNSDENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSTVINISIPENTLINSRFPIPSAVDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNKPVFKESQVEVHIPENAPIGTSVVQLHATDADIGSNAEIKYIFGAQVTSATKRLFALNNTTGLITVQRPLDREETAVHKLTVLATDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPINTKIALITVSDKDTDVNSKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGIKEFSFKIVAADTGKPSLNQTALVRVELEDENDNPPIFSQPVIELSVSENNRRGLYLTTVSASDEDSGKNSDIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITATDSDAGENKAVTLSILNDNENFVLDPYSGLIKSNVSFDREQQSSYTFDVKAVDGGQPPRSSTAKVTINIMDANDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDTDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPSAADVGLHRLVVNISDLGYPKPLHTLVLVFLYVNETAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIVAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDTVHEPINGTISLPAELEEQGIGRFDWGTTPPTTFKPNSPDLAKHYKSASPQSTFHLKADTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQNPTPGTGGKTLSPCRVPCGLPSGVPTVHCNCLACTATLLHTPSDYGKLIYRTDAAPSLATDTFSPTLVFSVRGQDLPLHEILSASCDNSAMQSQRRVTFHLPDGSQESCSDSGLGDHDPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQQPKSPLSTFAPQKDWLTKDRLVNGHTLTRNWKEDSNKNQFNDRNQYGSSDGHFTSGNHTSDIPLATLKPYKQVSGAVDSPKEQQL
The following text describes a protein:
Function:
Potential outer membrane protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion. This protein may be required for secretion and assembly of the CdiA toxin protein; Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of CdiA.
Subcellular Localization:
Cell outer membrane.
Sequence:
MSRFYYSILVAGVLLKIVAIPDASYGAELAPVQQSIHQQERQRALEERLAPPTPDVRLSAPSAFFSRIIFPLETPCFVINRIKISGAEPLPRWLPLQRIADQAQGQCLGAKGINLLMSQMQNRLVDHGYVTTRVLAPQQDLNSGTLALNVVPGKIRGVELTPDSNRYVTLFSAFPARAGTLLDLRDIEQGLENLQRVPTVQANMVLIPGSAPGETDIILNWQQRKMWRLAASLDDSGTRSTGRYQGGATLFLDNPLSLSDLFYVSAGGALQRRGDKGTNNLTGHYSLPFGYWTAGMTASRYDYYQAVAGLNGDINYRGESENVAFQLSRLLHRNASQKTTFTYDVLTRSSKNYINDTEVEVQRRRTSAWRIGLQHRHFISQAILDAGISYQRGTRWFGAIPAQEEYFGEATALSKILRLNAQLDIPFVVMAQNLHYNLQYQRQSTNTPLTPQDQFSIGGRWSVRGFNGERTLIADRGWWVRNDIGWYLPLPGHELYVGVDYGEVGGRSGAYLLGRHLAGSAVGVRGNVLNTRYDLFAGKPLSKPNGFKTDSLAVGFNLNWLY
The following text describes a protein:
Function:
Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici; Promotes hydrogen peroxide H(2)O(2) production and cell death.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MHLLVFFFFLQLLPLAISVHFNIPRFGPELSNLLYHGDAKPSSGGIVELISNYDYTCRVGWAIYAERIMLWDSTTGKLSDFTSHFSFNIDTRGLSRYGHGLAFFLGPVGFEIPPNSAGGFMGLFNTSTMDSPQSQIVMVEFDSFPNPEWDPKPLVEHVGINNNSLISAVHTPWNASFHSGDTADVWVTYNANTKNLSVFWTYKRTSNAQENTGLFYIIDLKEVLPEWVNIGFSAATGQFGERHQLQSWEFNSSLNFQGENRQSSKRTRIIVGVAVSVCVLAGGAIAGILISFRKRTKKQMMVRREGHTRNLTSINEDLERRAGPRRFSYEYLASATNNFSDERTLGKGGFGAVYKGYLIDMDLAIAVKKISRGSRQGKKEYITEVKTIGQLRHRNLVQLLGWCHDRGEFLLVYEFMPNGSLDAHLFGERRPLTWAVRYKISLGLASALLYLHEEWEQCVVHRDVKSSNVMLDSNFNAKLGDFGLARLTDHEVGPQTTGLAGTLGYLAPEYISTRRASKESDVYSFGVVALEIASGRRAIDHSDQDHEMNLVEWVWELYGHGNLQLAADKELHMDYEERQVECLMIIGLWCAHPDHNLRPSIRQAIQVLNFEAPLPKLPAKMPVPTFRAPSPSVSNGQSFTTSSSGLGLGV
The following text describes a protein:
Function:
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.
Domain:
The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
Sequence:
MASTSVPENYYVVPIGETQMVILKRYENLRLIGSGAQGIVCAATDMVTNKPVAIKKLSRPFQNVTHAKRAYREFILMNLVNHKNIIGLLNAFSPQREVEEFNDLYIVMELMDANLCQVIQMDLDHERLSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAVEAFMMTPYVVTRYYRAPEVILGMGYGENVDVWSVGCIFGELIRGRVLFPGADHIDQWTRIIELLGTPEPQFLARLQTTVRNYVENRQKYQPVPFETLFADNMFPPGADNARLTAAKARDLLSRMLVIDPEKRISVDDALAHEYVNVWYDASRGSCSSAGPSTILLVDGEHTVEEWRAMLFAELQNYYRTHDVYGVGQRR
The following text describes a protein:
Function:
Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.
Subcellular Localization:
Nucleus.
Sequence:
MGGTNAPPTLVGESFPSAEKRRKLQGELRARRLGRDFLGWKWPASRMAKVEARGRLWLESPPGGAPPIFLPSDGQALVLGRGPLTLVTDRKCSRNQVELVADPETRTVAVKQLGVNPSTAGAQELRPGLEGSLGVGDTLYLVNGLHPLTLRWEEARTPELQPDTPPGTPPVPPHEEEEEAEPPKKQMRKSSPGWESFEKLLVFTAPGVKPRGKVASFDLDGTLITTRSGKVFPTGPSDWRILYLEIPRKLRELDAEGYKLVIFTNQMGIGRGKLPAEEFKAKVEAVVEKLGVPFQVLVATHAGLYRKPVIGMWDHLREQGNEGVPISIGDSVFVGLLVCRPPGEAAPPCPAPRFALNLGLPFATPEEFFLKWPVARFELPAFDPRTVSRSGPLCLPESSSLLSPDPEVVVAVGFPGAGKSTFLREHLVSAGYVHVNRDTLGSWQRCVTTCEAALKQRKRVVIDNTNPDLQSRARYIKCARDAGVPCRCFLFSASLEQARHNNRFREMTDPSHVPVSDIVIYGYRKQFEAPTLAEGFAAVLEIPFRLHVAPQLERLYRQFSEG
The following text describes a protein:
Function:
Putative oxidoreductase.
Sequence:
MTTITPCFIITGASSGIGEKLAKIYSERNINIVLAARSTDKLNKLALELKSINKFSNKYLVVSYDASKESDCKNLIEIVIKQFGRIDLLLLCAGVSYHNSFKDTTDLNVYRQMMDINYFGYMYTTYYALPYMIKQQQKQSTNNNNNSNNKPQIAVISSISGALGLPLRAGYCASKFAVNGFFQALRLEVQSYVDITLLLPTTVNTPMRSHSLGDPNEKKLIHFHGEDDSKKMTIDQCCEIVIAAIDGRKKKVAFPFSNFLASVLHPIFPNYIDKILLKKAGGTNLINSNSNSNNNNNNTLKSKL
The following text describes a protein:
Function:
Integral part of a neural sensory system in the antenna that provides the neural basis for the response to environmental changes in temperature (thermosensation). Specifically, required for thermosensing by the cooling cell. Plays a role in heat seeking and heat-stimulated blood feeding behavior.
Subcellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein.
Sequence:
MFKRIVLAVINLVFLIVSTTAFASLHYPESFNQQLIRYKGRDSSNGYFELASEAYYTGTYDLVEELNETATCLRADCREQSNSSPVVRDRRRVDPTFYGHPKTREQIWERNFAHVIEDNRQTLSLVTLLNKIILKYLHSCIPIVLFDTYVATTENYMLEALFSDFPITYITGRIGPNYTLDNPGILEPTGPQCRSYIIFLADVMMTRKVIGPQMNSYVVLIPRSSQWKLQEFLAAKQSRDIINLLVIGESYSVDKRINNEQPYVLYTHELYIDGLGANRPQVLTSWIGNKFSRNNVNLFPRKLRKGFSGHRFTVKAAHQPPFMIKRLSTDGVGNVNIRWEGLEMRLLRVMAQYLNFTYDIIEPGRTELGPGDAVVEEIKRGQGDMGLAGIYVTIERNLATEMSVSHSTDCAAFLTLMSSALPRYRAILGPFQWPVWVAVILIYLLAIFPLAFSDKMTLRHLLGNWSEIENMFWYVFGTFTNSLTFQGENSWSNTRKTSTRMLIGIYWVFTIIITACYTGSIIAFITLPVEPERIDGIEQLSRGFFRVGTLDRGGWERWFLNSSHKQTNKLLKDLRFVSSVDEGIRNVTEAFLISYAFIGSKGELEFLIKSNLSHQFENKRYGLHVSRECFALYGVSMVFPPNSVHRDPINNAILYMQEAGLIGKLNRDVTWETMKTKDGRRKEASVGEVLRSTAPSERGLTLADTEGMFLLMLFGYVVALGVLISEWVGGCTNKCREVLKERAERLKAAAAEIAAAATAGSDNGSLPVSSPTSTNRNSPHKRTGPNGVENSLPASGNGSATVRRIRLTGEDSENEPNEYDVPPDAASDGGSSLQRHSLSECLSEVSAHTMQDLYNGPDRRHSTIVFLDGQLMSEEEAQRKVARSKSRHRHSLSSVLEREVSQLFRFLGKESPHSARADESSDAGGLVRRGAGRERKEMKVAVEINARATEEGQQGPGAAVGRRSIEATFGEKLLH
The following text describes a protein:
Function:
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
Sequence:
MEVFRAVMLTGSINAAAKMLYVSQPAVSKLVAHTETTLGLRLFERAKGRLVPTAEAQALYREVEQVYQSALRVDEFARALALGPASLLRVACSPSLAPGVVAPAIVELKRQLPGLSVDWHTALMADLPLEVLSKTVDVAITSLPIEHEHLEAVPFMRGRMVCALPPDHPLAARERIALADLAQEPMILFRRDIPFGTIIVRACQQANVELTSVVD
The following text describes a protein:
Function:
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MVEVHAKSKMGLNGSSGSGTQPINRRKNLSQQIWDVVQLIGDVVLLWVLVLYSLGERFYRYIVPVPERPVKGEIVLITGTGHGMGKELALLYASKGATVVGWDVNTKSNEETISEINARGYPKAYAYYCDVSNKDSVFEVAKKVLKEVGDVSILINNAGIMPTHPILDQTKEEIEKTFAINVFAHFWTIQAFLPTMKKNNHGHIVALSSCAGLFGLENLVPYCGTKFAVRGIMEALHEEFRQEKNCKIETTCVCPYMVDTGLCKKPKVRFERLMPLLNPRYAAKSIMKAQQTQQKLVSIPGYLVNLNDFVRVLPLKAGLYIKDFINSGVESDL
The following text describes a protein:
Function:
This endogenous retroviral envelope protein has retained its original fusogenic properties. Together with Syna, participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. Synb is specifically involved in formation of syncytiotrophoblast layer II (SynT-II). Promotes myoblast fusion, and may play a role in regeneration of damaged muscle tissue in males. May have immunosuppressive activity.
Miscellaneous:
MISCELLANEOUS: The mouse genome contains a high percentage of proviral-like elements, also called endogenous retroviruses (ERVs) that are the genomic traces of ancient infections of the germline by exogenous retroviruses. Although most of these elements are defective, some have conserved a functional envelope (env) gene, most probably diverted by the host for its benefit.
Subcellular Localization:
[Surface protein]: Cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the membrane, but localizes to the extracellular surface through its binding to TM; [Transmembrane protein]: Cell membrane; Single-pass membrane protein.
Sequence:
MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT
The following text describes a protein:
Function:
DNA-binding protein which binds to the promoters of let-60, lin-14 and lin-28, possibly to regulate genes involved in hypodermal and vulval development. Together with miRNAs mir-84 and let-7 may direct terminal differentiation of the seam cells, exit from the molting cycle, and vulva formation. Does not regulate the expression of mir-84. May promote hypodermal differentiation in association with swsn-9, a component of SWI/SNF chromatin remodeling complexes.
Subcellular Localization:
Nucleus. Note=Localizes to nuclear foci in embryos and larvae. Localizes to DNA. Partially co-localizes with swsn-9 in hypodermal nuclei.
Sequence:
MLKPPIITSNDNNNTKVAENLNDLNNKGKMSGQQIESFSPWHAQTSSSAVTGTSELFGSTYAMLSDHSVYPEQWSGKQLSQSVLFEQPQIQPLVGNSYDPPVRFDPPYAYRATATGYMPTVPGLSTNSSPYYPRTSGYAAGQQFYAPSLSGVPNTQQLILAAQVAQASNVQQQLQQQVLRPEPLRPATQKSTNGVHRSTSNSSAETLRNNSVSAATVSPSDDNSLNSPALTSSGSAGSGTPPLGIDLNNTDLESGDEERVMCMACRGVYPSRRSLTGHIGRNEKCREIIGRNYLDALAQGVNPPIPGTDAAIKSGAITTGADGMSPVCPFCDRFISHYKGNIRRHINQCRKSAEPMKRHRVEAHEKQSPKKKVKKEQNEMYQHEYNDHDSSSMSGGMMNSPKISPPSSSFYGANSSDLCSPGEYSNSAYEPYPTPMLENTERTSTETAVLQDAYICEDCDFVTVYKGNMKRHLNTCHPQPEFKSLKEWDQKLEGMRASNLGISGDRLQERLAAHKANSSRGRKPRKKKENNTEESESIDFKNILNSETGALLESLASSSSSMGGYSNGNNFQPPPPPPPMLL
The following text describes a protein:
Function:
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MISHLLPTTSLTIHMPSIILYPIYFDKSRPRRFRCVPKDKAILNPLAKNIADVVRDLGYKCKLEPLKTHPADWVNPGRVEMVLPEKIQKKYVINEIAKVLLLRPTVKTDPLSLPIQNVPARLPENPPAYPKGVLGNTILPLHSPALSGGGISENMFQEMMQEMQKQPGLAGGMNPMAALAGMGGPAPPMPTPQASSSQRKQKSIEPEYDLDLE
The following text describes a protein:
Function:
Has a role in meiosis.
Subcellular Localization:
Nucleus.
Sequence:
MSFPYQHTSRSQVQPPLAAPGLSMFAPVSSSNSANSASSVAALLSHAPMYGLGQRRPSFLPGVSVPDTLSVRSGFSIPSSSHHPSAVPSLLSQHRLQQPQPRLYPSAPLNYYWPSYQSVPSAAPPPPSQQRYMPDSAVAYNPNQDQFGNSVNVSAACNNVSAPLIANNCAPSFYQSRHPVADVPVTNNTATTTSETDNTIPGNLNMPSVANVQQRISPVCKTNMEDQEETVYTGGVAAKLDYKMDQMVEYLSIMTCKLYARFLNNAQMHSLANSLPGLVFSFRKVVTQILTSTRLPRASCLLALSYLSDRLDAASQTTDFVNQWTKESLFFQICALLTTALILANKFLDDNTFTNQSWSQVTGFRTALLNSFEQDWLASMSWNLSPGPRGQKAWEWWSASYSLFTSSNATYSGEQKTYSPTTLSTNAPPSPSSGRSCSNCNYYYPYTPVGYYPVYNRYAMT
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication.
Miscellaneous:
MISCELLANEOUS: Present with 80 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
Sequence:
MNDDSQDKIIHDIRIQLRKAATELSRWKLYGSSKWAAEALAGLAEAIDVDQTHSLADESPLRNKQGVPKQMFEIPQNGFGLSETEYDLYLLGSTLFDAKEFDRCVFFLKDVTNPYLKFLKLYSKFLSWDKKSQESMENILTTGKFTDEMYRANKDGDGSGNEDINQSGHQRANLKMVSNEHESQSNISSILKEINTFLESYEIKIDDDEADLGLALLYYLRGVILKQEKNISKAMSSFLKSLSCYSFNWSCWLELMDCLQKVDDALLLNNYLYQNFQFKFSENLGSQRTIEFNIMIKFFKLKVFEELNGQLEDYFEDLEFLLQVFPNFTFLKAYNATISYNNLDYVTAESRFDDIVKQDPYRLNDLETYSNILYVMQKNSKLAYLAQFVSQIDRFRPETCCIIANYYSARQEHEKSIMYFRRALTLDKKTTNAWTLMGHEFVELSNSHAAIECYRRAVDICPRDFKAWFGLGQAYALLDMHLYSLYYFQKACTLKPWDRRIWQVLGECYSKTGNKVEAIKCYKRSIKASQTVDQNTSIYYRLAQLYEELEDLQECKKFMMKCVDVEELLEGIVTDETVKARLWLAIFEIKAGNYQLAYDYAMGVSSGTSQEIEEARMLARECRRHM
The following text describes a protein:
Function:
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
Sequence:
MRVLVIGAGALGGYYGACLARAGGDVTFLVRPARAEQLRRDGLQVVSPHGDFAVQPKIILASDLKEPFDVVLVGVKSYSLDDAMAQFAPAVGANTMILPILNGLKHIDALTARFGAARVLGGLANVSAGLDADGRVVQFMANQTIVFGEIKGSLSERALALEALLQVPGIDVRASEAIMQDMWEKFVQLSTLAGITCLMRASIGDILAVPNGEQSIFRLFAECCTVATASGFEPRAPFIEFDRKLFTTLDSPLKASMLRDIERGSITEAEHILGDMANRARALGIDTPLLDLARAHVAAYEVGRRRAAG