lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
Subcellular Localization:
Nucleus.
Sequence:
MLWVLDRVGFMDMSKFWDEDAIVQRVFIWIIMVNATKGIFISCDIPMAQFIINLNATQPASSKFIIHVLDSTHLFVQPNVTEMIRSAISEFRDLNSYEKPA
The following text describes a protein:
Function:
Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs.
Sequence:
MADAAAAAPAQEEDPPPPCDPETLARGYQLEALERAVAGNTVAFLETGAGKTLIAVLLLRAYAHRIRSAPPPCFAVFLVPTVVLVGQQARVIEHHTDLRVEQFYGEMGVDYWNADTWRRAVDGAEVLVMTPQILLDNLRHCFFRLRDIALLIFDECHHAHGNSPYANILKEFYHPQLNSRPSDPIPRIFGMTASLINSKTLQRSDYSVKISELENLMNAKVYTVESESALSQYIPFATTKVVQYDDSIISSELYCHAIGCLNRLERKHLEFLKGKLHDSSLENAEKRIKQLSATFLYCIDNLGVWLAAKAAEVLQSRKESCLSFWGEKLDEKVEEFVRNYMEDAYSDLSEIISKMTKRGIQRHIGEDFAADLQDGLLTPKVHFLIKSLLEYRHKQDLRCIVFVERVVTSIVLESFLSTIHQMSGWIIRYMAGKNCGLQHQSRKEHTEIVDSFRRGKVHLIVATQILEEGLDVPTCNLIIRFDPSATVCSFIQGDAVALSKTQKFLAGGQIMREESLRLASTSCQPLPNTMCQEESYCVQSTGAVVTLNSSVQLIYFFCSKLPSDEYFKPVPRFNIDKALGTCTLHLPKSSPIQTIYAEGEGSVLKRVVCLKACRELHAIGALSDSLLPELSVPYEDGPDIVVDKYQKEQPNYFPEQLVDSWLSFSRLGLYHCYEISLEWCSKTANSPAEIVLAVKCDMGSDFISNSFKMWGVQDHVSVTMRYIGIIHLNQEQVIVARRFQTAILSLLISNNQLEVRDSIKNSLEMQASPGVVYLVLPLVSGKIDWCSIKFSASPMLEVTNKDMRHCHSCKDTNLVQTKDGPLCQCMLQHAIVCTPHNGMLYAVSGFLDLNANSLLHRSDGSVVSYKTHFKTRHGLDLTCEDQPLLAASMLLKVRNFLHKCNYKNEKESTSTNAVELPPELCVVVMSPVSSDTLRSFLFIPSIMYRIQCMLLSVKLKIQLSQRMGQFDIPALKILEALTTKKCQEEFSQESLETLGDSFLKYITTQHLFNKYRHQHEGLLTEMKKNLISNAALCQLACSNNLVGYIRGEAFNPKTWIIPGIDHDACSDSKLILLSPNMYSVRKMSIKSKRIADSVEALIGAYLSAGGEQAAYLFLISLGMDIEFHKMPVERKITIKSEEFINLRSLEVMLGYDFNDPSLLVEAMTHGSYQIAGTTACYQRLEFLGDAVLDHIFTDYFYRQYPECTPELLTDLRSASVNNNCYAHAAVKAGLHKHILHSSSALHKRMADYLENFKQSFSGPSHGWEAGIGLPKVLGDVIESIAGAIYIDSKCDKEVVWRSMKRLLEPLATPDTLDVDPVKELQELCGREAYSITYNVIREDRVTSVVAEVQTKGTAFKAARTGLSKLDAKKLAAKAVLQDMKAADGAK
The following text describes a protein:
Function:
Methylates eRF1 on 'Gln-182' using S-adenosyl L-methionine as methyl donor. eRF1 needs to be complexed to eRF3 in its GTP-bound form to be efficiently methylated.
Miscellaneous:
MISCELLANEOUS: Present with 3390 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MLPTPYVKCDYDKVYEPAEDSFLILDCLEKEHDFLKQKFGNRLAIVCEIGSGSGIVTTFLMQNKIIPQENSIHLAVDINPWALEATLDTAKLNSCKSSFLEVIQADLNSSIRNNQVDVLIFNPPYVPAECVPDVPGSREEADQWLDLALLGGKDGMAITDKLLRQLEQILSPDGVAYILFCARNKPKEVIKRFVDTYKWNVKLIETRKAGWEVLSVYSFTR
The following text describes a protein:
Function:
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MDITTDTQQPAPSRTPQPPATEDTRPGRGVTRPGDRIFVGLSRGSGILVLVIMAAIAAFLTYRAVLAIGEDEANFFTSFEWNPTGSPPEFGIAVLAYGTVVSSIIAMAIAVPVSVGIALFITHYAPRKLGGLIGYVIDLLAAVPSIVYGLWGALVLVPHLNGLYGWLDEYLGWTGIFEWNGGAGRSLLTVGILLAIMILPIITNVSREVFRQVPRMHEEAALALGATRWEVIRMSVLPFGRSGVISASMLGLGRALGETMAVAMVLSPTFDITPSLLDPGGGTFAQNIASKFNEATQMGRDALIASGLVLFVITLLVNGGARMIIARRKEYSGANA
The following text describes a protein:
Function:
Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs).
Subcellular Localization:
Endosome.
Sequence:
MSWRFPLFGSSQQQQADPSFQDIPTQSWYPPSVVGSSSRPSTPTSSSASLHQRASDSPQSSSRGQPSPAEAAGIIARLKDKSIEELQRLLKDREAYNAFFNSLDQVKTQNNVRDELKKETLQLARENLEKEQRILELRNQCTIIRTTELAAAQDRLTDLERQKDDIMRSYSPAALLNKLQTSMAKLDEESEELHQKFLEKDIDLPTFVQKYKKLRTAYHKQALLHLAGQTSLR
The following text describes a protein:
Function:
Involved, directly or indirectly, in spore cortex biosynthesis. Affects only indirectly the expression of late sporulation genes.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAKQTFLKGTLILIAAGMVTRMLGFVNRVVIARFIGEEGVGLYMMAAPTFFLATTLTQFGLPVAISKLVAEASARGDHQKTKNILVMSLTITGVLSLIFTPLFLFFAPVMAETMLTDKRTLYPLLAITPVVPIIAISSVLRGYFQGKQNMNPLAMSQVLEQVVRISLVAVCTTIFLPYGIEYAAAGAMLSSVAGELASLLYLFVCFKYKKTIKIRKHFLQSIKNGKQTFTQLMSVSLPTTGSRFIGNLSWFFEPIVVAQSLAIAGVATVAATKQYGELTGFAMTLLTLPSFITYSLSTALVPAISEGMEQKKLQVVEYRLEQAMRLCLLSGGISVVILFVFADELMRVMYGSSGAAVFIKVMAPFFLLYYFQGPLQAVLQALNLAGAAMMNSLIGALVKTGLIFVLATRPSLGIMGAALAIVTGMVLVTLLHAATVSKVLPISIKIKEYALSFAVIVICGFISSAIKQYISFGASEAVNLAGWIAASAAIYMILLLVFRLIKKDELRRIPIIGRLIIR
The following text describes a protein:
Function:
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity). Promotes the anchoring of Liprin-alpha clusters at synapses. Recruits and keeps Nrx-1 levels high in active zones in the presynapse opposite the postsynaptic region.
Subcellular Localization:
Presynapse. Note=Localized in the active zone of the presynapse.
Sequence:
MQWKKKFTRLKAATGNSRVRRMLCCGRRKENGRSVPDVTASPGRAPPGPLPANQMPAMGNQQHHGNQQHHGNQQQHHGNQHSNHRGQSGSLSNAAGVKDPVMLQGDFRKVSGISSEIFRQIEAVENDHDPNTAAALEAVERRGEMIVRVLEPRCMGSKQAVDAAHKLMNKADARHTVQLVEIVKRPGQTLGLYIREGNGADRTDGVFISRIALESAVYNSGCLRVGDEILAVNLVDVTHMSLDDVVIIMSIPRRLVLAIRQRRGNRGTGSPGPPTLSRPEQKPPPVVVIKRDLRDEDLDETDRMPRPRSSRDRRTGDGREMTESRSRLGLGLNNYSPQSEQLDMYYNTRGGGGGAMGEPPNWGYKPPPPPSSVITEQPTKAHAFAPSHAYYQNAGTLESLAEKVHAFYPGQPGGPPVGPSRRMSTGTGNVGLAQQHARFPRSGSDQHLPRVEYSDYSNSLGRHSLLRSSLKPGTTGGAPMQVGVGGTLGRYGRYDQQRAGVSKYGPPSGGAQSLTRRSRPNLDYSSDTEATIGPRPSYYYYNRPAIGSMSRGSGGAGGGVGAASTAALLAGAADLNKFNSLPRERPGTRLQGIRSRMGDRLVDENDGNTSAPEFDVRRGRDLRQRITASPSIFTADEYRAWLRRAPSSSAIAEQMRMTRDMFAQPRAQRFSCSAENIHDALRNTESIYSSRNHILGTGTLDRNMGLTRPISALPVRSMSSQHIGGAGSIRSPSIRRMRQLLELSAGPASPSGSILSTGGHQSPAPTPSATLPRPHRQIDINPAEFAKYKLDKPIVDIGGISGMLWIHLLAGRGLRTAPEGAAGTATQGQTRDLYCVIECDRVHKARTVVRSGDLQFDWDESFELDLVGNKQLDVLVYSWDPQHRHKLCYRGAISLSSILRQSPLHQLALKVEPRGTIYIRMRHTDPLALYKRRGLPSLRAGYPTLFGADLETVVNRESKNAPGSAPVPIVLRRCVEEVERRGLDIIGLYRLCGSATKKRLLREAFERNSRAVELTPEHVPDINVITGVLKDYLRELPEPLFTRCLFQMTVDALAVCLPDDPEGNAKLMLSILDCLPRANRATLVFLLDHLSLVVSNSERNKMSAQALATVMGPPLMLHSASAQPGADIDHAQPIAVLKYLLQIWPQPQAQHQQMAQHMGGAAGAMMGGLVTAGSMSNMAGVASGRRGESTGQRGSKVSALPADRQQLLLQQQAQLMAAGNLLRSSTSVTNILSQGHPQLSATANNHLYQSVVGQLAQSHRALQQAVQQPYQLGGSVGSAIPDPSPLPLPGTPSPGSSSASTGSGSGSGKSTDTIKRGASPVSVKQVKIVDQPSSPYSIVMKKPPLQKDAPVEITTPTTQADTESTLGCKESNGTASRRGNVDFYDTHKTQAKSVVNEESSYSSKYTGSETKKIIPGNSSYTPSKANASGLSGGEDYKAMRNKSSATSSSSSSQATVLSAGSTATSAPTTSSDDSDDLVSYKSSASTNALLAQSQAMTTSQLMSKYLKREPRVQFTPIKSPESPSPPGSGDGLPKGTYQLVTPISGSSSKPGATTGAISKYTTGSVESSINANSQKLSSPSRLCNSKDSNSRTGTASSTTPATSMVSTGRRLFDSLASSSSSETETKTYIGGTTAASGAITTTIYTNDTKNSGSSSSKSGIGGGSGTGLGAVSGASSETRSFGSTLFGSSGLGNGNGSSHNHSSASPSPFTTTNGNGNHNTMHLYGTLPKNGTSTGAALFGGSANSSSYHSSASGSGAGTASSSGVSSMTGSTNSYDFYTSTSSTVSSSRPFANGGNNYHTLGTYRAQYAATNPFLDAFDEKPGSNGGNAHGEEKLGADKGHHRAAVMAFQSSGDSKNGSDEYDDIK
The following text describes a protein:
Function:
Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route) (By similarity).
Miscellaneous:
MISCELLANEOUS: Was identified as a natural substrate of the M.tuberculosis proteasome.
Sequence:
MSVVGTPKSAEQIQQEWDTNPRWKDVTRTYSAEDVVALQGSVVEEHTLARRGAEVLWEQLHDLEWVNALGALTGNMAVQQVRAGLKAIYLSGWQVAGDANLSGHTYPDQSLYPANSVPQVVRRINNALQRADQIAKIEGDTSVENWLAPIVADGEAGFGGALNVYELQKALIAAGVAGSHWEDQLASEKKCGHLGGKVLIPTQQHIRTLTSARLAADVADVPTVVIARTDAEAATLITSDVDERDQPFITGERTREGFYRTKNGIEPCIARAKAYAPFADLIWMETGTPDLEAARQFSEAVKAEYPDQMLAYNCSPSFNWKKHLDDATIAKFQKELAAMGFKFQFITLAGFHALNYSMFDLAYGYAQNQMSAYVELQEREFAAEERGYTATKHQREVGAGYFDRIATTVDPNSSTTALTGSTEEGQFH
The following text describes a protein:
Function:
Centriole-enriched microtubule-binding protein involved in centriole biogenesis. In collaboration with CEP295 and POC1B, is required for the centriole-to-centrosome conversion by ensuring the formation of bona fide centriole wall. Functions as a linker component that maintains centrosome cohesion. Associates with CROCC and regulates its stability and localization to the centrosome.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Midbody.
Sequence:
MATGDLKRSLRNLEQVLRSLNYPREVDCVGLVKGDIAASLPIISYSLTSYSPYVAELLVESNVELIAKNDLRFIDTVYKLLRDHFNYKPILTKKQFLQCGFAEWKIQIICDILNCVMKKHKELSGLEKTPSQQRKKISSIKSEPCSGAEKTSAEPVGIDVTGRFVTSGKKKAVVIRHLYSEDGVNIPEDPSADVHEAFDVCDLKTADLKIPELQVPEINCEQQDVKVNPEITALQVMLAECQEKLRKLTCLENRLDSLETKMKGKVMVNEKTWTNLLSRVTLLETEMLLSKKNDNYIEFNEMSEEYASSSDMDSLNPDRKSQEERQANIPLSSGYSTVSSDSTPRTSTVNYYGLKEISEETTIQKMERMKKMFEETAELLKCPNH
The following text describes a protein:
Function:
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
Subcellular Localization:
Cytoplasm, cytoskeleton, flagellum axoneme.
Sequence:
MDGKEKGSKKKKKSLSSFSAISNETNSSFMSSNVTNEEPNDEGDKTPENPEEESHMRILSLHRDLTAALINIQTAAVAIVATTKLENAQGTIAELQEKNEQSSQKIFEELIEGWSTAHQKEAHQDLLEALESQQHLCAAVIRDKKILINDLKQELNRRHESYVRTLRKNAEELNLVTVMMEEKMKIMTDVYREESEQMERIHQQEVEILLTKDKDQWEKQIKALCDKELQLLTERKKKVKEYEEKCHDKILGDVINNAKSKVSVKNLHKKVPSDLLVPKNNLHAQLAKQSKEMSTFLNGRIFSLKNDIKKLRETYTEKERELKNCTDKLYGEYQRSYQRVQRCNQMQMKTRHNSVDAKQFKELQQMIDGELNQLAQRALTIDSLICQYLGLPWKQDNMAMLELLSPIQEQVPNFGQLNYETDKCNQGMIESDNKEKEKLCKEALETSVDPLWDEMKSSAGCSGMMKAVEASPPTNSSIHHKPFLPPLKLHPGLKRESRESSEKQISSSWHGQVLDASEVGARWERLANVIPEEKVRMWEIAQKQLLQHHSVLREISDLSLETENLRQKNLQLKKQLQERGISVTNSCAFDPKEG
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MESTVPFLSPVSQSPENHFSFYHNFELFYMENIAQNNSFDQTQTLESPFSGLNVSGYPDLPDSGYQFGGGFARAGQDRNNNVIGEGTKVGPDVESWGAFMYSSYQLGSSRNTEFSILPSSNQTRLLSAAASAAGCTMPFGLNNNINRPSFNTSKLCNNNQTRPHWLHEPLNCLSLGDLRGRLVALAKDQYGCKFLQKSVEKASKEEIDMVFMEVIDHVCELMSNSFANFVVQKVVDVCSEEQRNQILLMVIKNRFRLVEICLNLHGARAVQKLLEKLTTQQQISLFMSALSPGAVALSKDLNGHRVIQYCLKNFSDEDNKYFLTVVANNCYQIAIDKCGCCALKHCLDHSNGEARSRLFQEIIANALNLAEDQYGNYVVQHILELKETQTTESLLRQLQGNYASLSCNRYGSNVVERCLLESEEPLTTRIIVELLRSPIVSTLLLDPFGNYVIQSALSVSKGFVFDALLNLVQDHYPIMRSHSYGKWVLAWFSRRKQLHM
The following text describes a protein:
Function:
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSSPSEFYKSLPPITKAYGTICLMTTVASHLGLYRLENIALIHELVFSEFQVWRLLTNFFFLGNFSMNFGIRLLMIARYGVQLEQGPFQRRTADFLWMMIFGAISLLALSIVPILRGAFLGISLVFMLLYICSREFPNAQVNIYGLVALKAFYLPWAMLALDVIFGSPLVPDLMGIIAGHLYYFLTVLHPLAGGRNIISTPRLVHKLVARARLEYPTNARVPQERTTGVAFTGRSYRLNSSTGRGFSLRRFWSS
The following text describes a protein:
Function:
Binds predominantly GDP, and also GTP.
Subcellular Localization:
Cytoplasm, perinuclear region.
Sequence:
MNHAELRRLFAACDGNQSGRVEYEDFTTVCRELNVPADDIRTLFNKFDLDGDGYINFNDFSSSFQEVSEALNLASLGNCLHSQRRAWDEFENTLDGDVAFYLGRQWDALSELYEGIHSTSDELLLQQFEDLIRALVTEIREHRMESEQLETSLRRTEEVSSSQLAEMEEDLQQQLIHTERRVREEEQKKLDESIAMLQIKHENELADLQTTIERLTKQYQEESKLNTPREDSVKLRAQIKDLMEENEELRASLMKAQMNVSILQVELDKLKNAFTDQKRQHERESDDLKKMVMEFQSYSSHIEMLQEMNKSLYDSNDGLRSALSQENASTKRQLSPRNEVLPRKMKPIRQSTMNQSSFTNEEDTLALVKCWAEKYLDSGVSVQSEMDAMSGIDYDSDDSHHSVETVHHSYSCVPSELEVSEVKPEALRSVARSTVGSISSSLRRRLSAFPVKQNEEDLLDTQDLAPVYRLVLAGDAGSGKSSFLLRLSLNEFRGDIQTTLGVDFQIKKMLVDGEKTNLQIWDTAGQERFRSIARSYFRKAHGVLLLYDVTSESSFLNVREWVEQIRESTDEDIPMCIIGNKVDLRAARPEGSCVSSIHGEKLAMNYNALFCEASAKEGTNVIEAVLHLAREVKKHVKLGRRSESQVKLSLHKRRKTLSNCCGV
The following text describes a protein:
Function:
Acts as an allosteric regulator of polarized exocytosis by promoting the targeted fusion of vesicles with the plasma membrane. Involved in maintenance of ion homeostasis in cells exposed to NaCl stress. May be involved in the targeting of the myosin proteins to their intrinsic pathways. Multicopy suppressor of RHO3. May also participate in the maintenance of cell polarity and bud growth.
Sequence:
MFKKSRHLKNVSNAIKSARVHDVSNGINSKFFDTKKICTYGINGRITVTTFDYTQSLLAVATTAGEIHVYGQKQIEVVFTLKNRPQIKHMRFIKGIYLIAVDEKSNIIVLSVHSKQILTTVFCPNSITCIETDPSLDWMLIGLESGSILIYDVDRNQMSKLKIENFQKSVFLPKERLSPVISIQWNPRDIGTILISYEHITVIYSFIDYKVKQHFFYQLEPYAPGGDLSTNIEKKRTPKVIQSLYHPNSLHILTVHEDNSLVFWDVNSGKLIHARSIFETHVNFPNPALKDCSFTETPAIFKVSWLCQRNPEYTSLLIATKATENPCLPQEITMIDLGGTPMYSVTSFDAMSKYYAKPVQQKLFSLIGKAPLINFLPLPKASPYFGGCHDTNLILLLLEDGELETLIYPAGSFSSKASIFPRSLAWVRPTVTTCIAQSVQKNLWLGMMTIAQSESFLKGGIPATRNIRRHETRSALLTGHSNGSVRIWDASHSEVTDNAVFEVNTAKVLNRATNLAIKNISFASETLELAVSSEVGDVILFKFETNKFYGQLPKSDALQLKFSRFSLDDSKTILVDVSDRGPTNVKQGFIPSTVIHAKKGAVSAIMNSNIGFVAVGFIEGTLIILDRRGPAIIFNENIRVISKAGSSYVSTVHFCVMEYGDDGFSSILMLCGTDIGELMTFKILPATNGRFEVKFTDATKTNNQGKILGINSFAKDTGYSCSATISKMQGLSKGIAIPGFVTISGANDIRLVSPGKSKDTHALFKYPIATSGLSFIPIIDGKGERKLSTIMIVLLINGDIKVLTVPELKEVKNLRCPVPLSAQYVENSSILENGDIVIRTGKFQASLISVLNESATGTNHTADISQHTPIDTLYNPDLKIGYRPQVNSLQWARGTIYCTPYQLDELLGGIERPESKYEESAIARGCISSSSSNAARKLPPGTEDHRYARPVRSSGRSNGYGVLKSVSRAIETRLDTVETTINDYATTMGQTMNDAMEETGRDMMKSAVGF
The following text describes a protein:
Function:
Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
Subcellular Localization:
Peroxisome.
Sequence:
MLQEACIVSVSGESSKSSGNHGEVTGHSCSGVIVDRQRGLVLSHGVAFSPYLPDEFTSHQVRRQGWYKPQDTDRFNIEVIVRPRSEKGQPEASDRFLQPIQQPIPAATTAGGKLASELDSPPEKKCSAELLLLWRCIDFDDAVRKLMPKYDNWHFDEPPNNPADSRRDPSHQIEAVQSCVKTDWMAEVSLSWFALLKLKESEKGAESSAVVGVEQAQIGSPVMAVGTPFGVLCPSVFMNSLAKGIVCNTAGKGGALILTDARCLPGTEGGPLLTVDRDGKWMLLGLVAAPLCWKANEWIGLSLVCSFHAVLDSLAHLVPWPLIPAAAVIHSIQEPPHPALSQVEKSIVMIEAGEIWGSGVVVHVDESKVYLLTCRHVIGSSSKVKVVMCHAQKVRVTGNVVYATPSESVYDLAVVEFPNPRVKLVPVRETRRYDQGEQCFAVGYALFGQNQHMKPTVTAGVLSNVVSWQGNPIMLQSTCAVHAGVSGGALFNQQGQLMGIVVSNAKDVQLKACYPHLNFIIPSTTFAKAMDRFVQTKDAGCLSEFDSNNHYLQDVWKLQEPKPLLQSKI
The following text describes a protein:
Function:
Putative ferric-chelate reductases reduce Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MMQALTMRSWLATLVTALLAVAIWPDPGQSLPQGAPETVCDTMLPFHSGGSVLPQNSVSPFSVETSSSTLGQGQTLRVDLTGVPAGLSFGGYMIQARNRNPPHQIIGQFGPARDGTIKLMNCENSVNNSATHSNAGPKQQVILEWQSPVDFLGQVVFNATIAQSYNEFWVGVPSQPVQIVRRDLSAAPPLPTQSPSAPAGTTRAPYVPPSYVAPNNVVAVSSDPIYNGCGQSKNCFGFPDGCVATKSCTSITVVTVRGDVFEFEIQSGKGTNAAYVAVGLSDDAKMGDDLTTECVPENGRVNLYSSLTSASPYSAVRSNVNQNSARLLDASIVDGVIYCRVQRDAVTNVQGRTFDLRNGKYHLLVASGSSLKENSVGYHDIGRLPSAQPINLAEVQDLSGSSRLLIQLHGAFMIAAWIGTTSLGIIFARYFKQTWVGSQSCGTDQWFAWHRLLMVTTWSLTVAAYVLIWVELKQAVWHAHSIIGLITVILCFIQPIGALFRPGPNDKKRPYFNWGHWLGGNLAHILGIVTIFFSVKLPKAELPEWMDWILVSFVVVHVLVHLIFSIGGMASERHLSQRANTFQMGDMSHHQQHAMRNGMSMERKMDAPYAGMRKGLLGVYGVVLILFVTVLILLVVLAPIEQFLGKS
The following text describes a protein:
Function:
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i)/G(o) and beta-arrestin pathways inducing cellular responses via second messenger pathways such as intracellular calcium mobilization, phosphorylation of MAP kinases MAPK1/MAPK3 (ERK1/2), TYRO3, MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MEDLEETLFEEFENYSYALEYYSPGTDLEEKAHLGVVHWVSLVLYCLAFVLGIPGNAIVIWFTGFKWKKTVTTLWFLNLAIADFIFLLFLPLYISYVAMSFHWPFGICLCKANAFIAQLNMFASVFFLTVISLDRYIYLIHPVLSHRYRTLRNSLVIVIVVWLLASLMGGPALFFRETLESNNRTVCYNNFHEQDPDLVLMRHHVLTWVKVIVGYLFPLLTMSICYLSLIFKVKKRSILASSKHFWTILAVVLAFLICWTPYHLFSIWELTIHHNSYFHQVLQAGIPLSTGLAFLNSCLNPILYVLISKKFQVRFRASVAEILKYTLWEVSCSGTVSEPLRNSETKNLCLLETAQ
The following text describes a protein:
Function:
Mediates responses to the synthetic auxin 2,4-dichlorophenoxyacetic acid (2,4-D). Not involved in the response to indole-3-acetic acid (IAA). May interact with RUB modification-related components and may regulate the culling-ring ubiquitin E3 ligase complex (CRL) activity.
Sequence:
MDRYWEQDPMRPMVYRDFLGEMEYPGYSMPMQMEIDEDDFGPMDMQFEVGGISPFQMKPEDSDFFNKFEDDFDDSDIN
The following text describes a protein:
Function:
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
Subcellular Localization:
Cytoplasm.
Sequence:
MARKKTLDFEQSLTELQTLVERLESGELSLEESLGAFEQGIRLTRECQTSLSQAEQKVQILLERDGELSEAPFDAEGDEA
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MTNLNATVAAVLVMLAFLAGQSVAGRYYYDKVQDKVRKEVEKAMAKNPSVGPALVRLVFHDCWVYGCDGSVLLDSTPTDGTNTEKKAANNIGLAGFEVIDAIKQKVGTDASCADIVAFAARDAADILSGGKIFYTIPGGRKDGVVSSAAVADANLPHPDFNFDELKDNFNASSRGSSFTVEELVVLSGAHSIGVAHLSSYQDRLGPDSTPIDSDYQEALNKATPPGLLKTGQNPTVTNNVRDETDAFQKDAAYNPVAMGVNPKRGVLDNSYYHNNLVNKVLFKSDWVLRTDDFAASKLDEYKNNPAEWNSDFAAAMVKLSSLPAQGNKLEIRKNCRVPNPQY
The following text describes a protein:
Function:
Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.
Sequence:
MIYPQIMHKPALPWVFRRPTQEDGLSIHELIAQCAPLDQNSAYCNFLQSSHFQTTCLMAEQQELLVGFVSAYRKPEQQNELFIWQVAVHPSARGKGLAYQMLKHLLAREDLADITVLETTITRSNQASWRLFQKLDREQGEQGSVSTFLDETCHFEGEHDTEYLYRIPLQSSN
The following text describes a protein:
Function:
Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development.
Sequence:
MAPKKNSAKRPQPSTPKPSAPARIVKVQSSDGHILQADVRALLLSSTLAATIKGYDDENKPLEKLEVNNVVGFTLKLVLEWCEKHKEDDPAIAQAEKDKKNIFIPSWDRHFLTKLPMGNLFDLITAAYHLDITGLINYGCKTVANSAKGKSTEEMRELFGIPEPWEQPSTSTATWDD
The following text describes a protein:
Function:
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
Subcellular Localization:
Cytoplasm.
Sequence:
MTEETPGFEEKPDVPSGATPDDAEPQAASEEGAAPAGDASENAGLVAQLDQVRTALNERTADLQRLQAEYQNYRRRVERDRVAVKEVAVANLLSELLPVLDDVGRAREHGELVGGFKSVAESLETTVAKLGLQQFGKEGEPFDPTIHEALMHSYAPDVTETTCVAILQPGYRIGERTIRPARVAVAEPQPGAQTVKPAEDAAEAQDSSGAEDDAGTKESGGPDEG
The following text describes a protein:
Function:
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
Subcellular Localization:
Cytoplasm.
Sequence:
MVRIVPSARRTRAPAKLDGRSTPDIAMSLVTTASPLTTADTYTPAADSDAPPAVRGELVINLPMRHAGQRELRLRYELVGAEQAPVVFVAGGISAHRHLAASAVFPEKGWVEGLVGAGRALDPASRRLLAFDFLGADGSLDAPIDTADQADAIAALLDALGIARLHGFVGYSYGALVGLQFASRHAARLHTLVAVSGAHRAHPYAAAWRALQRRAVALGQLQCAEHHGLALARQFAMLSYRTPEEFSERFDAPPELINGRVRVAAEDYLDAAGAQYVARTPVNAYLRLSESIDLHRIDPAAVAVPTVVVAVEGDRLVPLADLVSLVEGLGPRGSLRVLRSPFGHDAFLKEIDRIDAILTTALRTTGETA
The following text describes a protein:
Function:
Component of the phage ejection machinery. Pilot protein for the formation of the tube that conducts the genome into the target cell. Probably involved in penetration of the bacterial outer membrane and for making the peptidoglycan layer accessible to the viral transglycosylase. Essential for viral infectivity.
Subcellular Localization:
Virion membrane; Single-pass membrane protein. Note=Part of the capsid inner membrane.
Sequence:
MEKVKAWLIKYKWWIVAAIGGLAAFLLLKNRGGGSGGGGEYMVGSGPVYQQAGSGAVDNTMALAALQANTQLSAQNAQLQAQMDASRLQLETQLNIETLAADNAHYSTQSQLQLGMAQVDLSKYLGDLQSTTSTALAGMQSDTAKYQSNIQLQAENIRANTSLAEIDAQKYIVGKQADIAKYQAKTERRGQDYGFALGLLNFGGKFF
The following text describes a protein:
Function:
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
Sequence:
MHNYKLTIQYDGARFKGWQRLGNNDNTIQGKIESVISEMVGKEIEIIGCSRTDAGVHALNQVANFQSDEKLVEHKVKKYLNQYLPNDISITNVEEVHDRFHARYNSKAKTYLYKIWNEEHTNPFMRKYSMHVNKKLNVKSMKAAAKHLVGSHDFTAFSNAKSKKKSMVREVYTLDVMEEAGFVQIRVSGNGFLHNMVRKIVGALIEVGLGQLDAEAIPNILEEKQRNQINCLAEASGLYLENVEF
The following text describes a protein:
Function:
Involved in the negative regulation of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MDTSSVGGLELTDQTPVLLGSTAMATSLTNVGNSFSGPANPLVSRSNKFQNSSVEDDDDVVFIEPVQPPPPSVPVVADQRTITFTSSKNEELQGNDSKITPSSKELASQKGSVSETIVIDDEEDMETNQGQEKNSSNFIERRPPETKNRTNDVDFSTSSFSRSKVNAGMGNSGITTEPDSEIQIANVTTLETGVSSVNDGQLENTDGRDMNLMITHVTSLQNTNLGDVSNGLQSSNFGVNIQTYTPSLTSQTKTGVGPFNPGRMNVAGDVFQNGESATHHNPDSWISQSASFPRNQKQPGVDSLSPVASLPKQIFQPSVQQQPTKPVKVTCANCKKPLQKGQTAYQRKGSAHLFCSTTCLSSFSHKPAPKKLCVMCKKDITTMKGTIVAQVDSSESFQEFCSTSCLSLYEDKQNPTKGALNKSRCTICGKLTEIRHEVSFKNMTHKLCSDHCFNRYRMANGLIMNCCEQCGEYLPSKGAGNNVLVIDGQQKRFCCQSCVSEYKQVGSHPSFLKEVRDHMQDSFLMQPEKYGKLTTCTGCRTQCRFFDMTQCIGPNGYMEPYCSTACMNSHKTKYAKSQSLGIICHFCKRNSLPQYQATMPDGKLYNFCNSSCVAKFQALSMQSSPNGQFVAPSDIQLKCNYCKNSFCSKPEILEWENKVHQFCSKTCSDDYKKLHCIVTYCEYCQEEKTLHETVNFSGVKRPFCSEGCKLLYKQDFARRLGLRCVTCNYCSQLCKKGATKELDGVVRDFCSEDCCKKFQDWYYKAARCDCCKSQGTLKERVQWRGEMKHFCDQHCLLRFYCQQNEPNMTTQKGPENLHYDQGCQTSRTKMTGSAPPPSPTPNKEMKNKAVLCKPLTMTKATYCKPHMQTKSCQTDDTWRTEYVPVPIPVPVYIPVPMHMYSQNIPVPTTVPVPVPVPVFLPAPLDSSEKIPAAIEELKSKVSSDALDTELLTMTDMMSEDEGKTETTNINSVIIETDIIGSDLLKNSDPETQSSMPDVPYEPDLDIEIDFPRAAEELDMENEFLLPPVFGEEYEEQPRPRSKKKGAKRKAVSGYQSHDDSSDNSECSFPFKYTYGVNAWKHWVKTRQLDEDLLVLDELKSSKSVKLKEDLLSHTTAELNYGLAHFVNEIRRPNGENYAPDSIYYLCLGIQEYLCGSNRKDNIFIDPGYQTFEQELNKILRSWQPSILPDGSIFSRVEEDYLWRIKQLGSHSPVALLNTLFYFNTKYFGLKTVEQHLRLSFGTVFRHWKKNPLTMENKACLRYQVSSLCGTDNEDKITTGKRKHEDDEPVFEQIENTANPSRCPVKMFECYLSKSPQNLNQRMDVFYLQPECSSSTDSPVWYTSTSLDRNTLENMLVRVLLVKDIYDKDNYELDEDTD
The following text describes a protein:
Function:
Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
Subcellular Localization:
Cytoplasm.
Sequence:
MDGSNLTSDGQKELQTFLNFFNLKKQEAMREIELEFKDFSKFQVQDTLYNKDDVQELFKKLEGSLEVLMNKEVSKIIYMCGVYVKIFLSVCSDQDFHADFNFIENVKIIEQMKILEKGGTIVEDKPLQSKVRYSRLPTLDTALQKQMEETVKENDFLKQYNQKLQNELVVLKKEQVQDADQVGSFQDQINQLKQENQQLKQEMEKKLNDCVQFKTLKQMIQEKNQQIKELQMKLQ
The following text describes a protein:
Function:
Vacuolar Fe(2+) uptake transporter.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MKDFGSAMLLALETNDHCIQTIRELGEKAEAADAPGNELLQLARWLRAAILGANDRLLSTTSLMLGVNAARDDRQSMVFSGIAGALAGALSMAVGEFVSEAICEEEALPNPYKATAASALAFLCGSLFPLLPAIFVAQHTLRVVIVMVVASVKICLKFESNVKFRIFRIGYVADVRN