lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a dual, essential role in magnetosome formation; required for magnetosome vesicle formation as well as biomineralization (Probable). Probably binds and transports iron (By similarity). Requires heterodimerization with MamM for stability (By similarity).
Miscellaneous:
MISCELLANEOUS: This bacteria makes up to 20 cubo-octahedral magnetosomes of about 45 nm in diameter which contain membrane-bound crystals of magnetite (Fe(3)O(4)); MISCELLANEOUS: Expression of just the minimal mamAB gene cluster (amb0961 to amb0978), including this gene, is sufficient to form a minimal magnetosome chain with small magnetite particles.
Subcellular Localization:
Magnetosome membrane; Multi-pass membrane protein.
Domain:
The C-terminal domain (CTD) is probably responsible for hetero- and homodimerization (By similarity). The CTD assumes a V-shaped, dimeric metallo-chaperone-like fold and binds 1 Fe cation per subunit (By similarity).
Sequence:
MKFENCRDCREEVVWWAFTADICMTLFKGVLGLMSGSVALVADSLHSGADVVASGVTQLSLKISNKPADERYPFGYGNIQYISSSIVGSLLLIGASFLMYGSVMKLISGTYEAPSIFAAVGASVTVIVNELMYRYQICVGNENNSPAIIANAWDNRSDAISSAAVMVGVIASVIGFPIADTIAAIGVSALVGRIGLELIGTSIHGLMDSSVDTELLQTAWQVAMDTPMVHSIYFLRGRHVGEDVQFDIRLRVDPNLRIKDSSMVAEAVRRRIQEEIPHARDIRLFVSPAPAAAARA
The following text describes a protein:
Function:
Serine protease which also acts as a protein chaperone. Plays a role in the parasite development in host erythrocytes possibly by protecting it against thermal and oxidative stresses.
Subcellular Localization:
Cytoplasm. Parasitophorous vacuole. Host cell membrane; Peripheral membrane protein. Host cytoplasm. Note=Localizes to the cytoplasm and cell membrane of host erythrocytes.
Domain:
The PDZ domain is dispensable for protease and chaperone activities.
Sequence:
MDIIFCTPTYCKIMLMIIMLISLRTRCDTNNFLNCSVEKEEGEEEIISTNLKRINDDMNILGRILNDERNIKITDIVEMLQNEYDDKKKKKKKKKYIYRKKKSNNKINEINSVQHFNVKENILNEKKKNPLNDNFKNPKLRKHSPNNKKNKNKIGQIKFHIVGYDKKKITKYLTPSMISSIQKRLMNKNKKTNVNVNMSNGRVLPFFPKEYFLHSSTHEKKDKMATKKNNKEESIINERLLENLENISLSRTIKDIRGEEGNERKVKEEDNNIKEEGNSFKKYFKGVVKLYVDITEPNLEMIWQNYPPKSITGSGFIIEGHLIITNAHNISYSTRILIRKHGNSGKYEAKILYVAHDVDIAILTTDDKTFFDDVYALHFGALPSLKDEIITIGYPAGGDKLSVTEGIVSRIDVQYYKHSNYKFLLTQIDAPLNPGNSGGPALVRGKVVGICFQSYKVSNNISYIIPSTIISHFLLDIHKNKDYTGYAFLGVKYEPLENPSLREALGLEEMERKKIIKKNVGILITEVFEGHMSKQDDKYHDMDNKHHNVGDTHHNVGDTHHNVGDDHTDNLQGDTDYCTYILNSNIITSDKKNIYSDKKKKKIYSDNNNNNNNFNYYYNMHGEDEQSCYGLKKNDIILRVDGKDINNDGSVILRDNETVGFQHLFNEKFINDLCIIKIVRNKKIKSVMVKLYKVKYLLNQHNWDKRNKYFIYGGIVFSILTRSLYVYTQNPEINKLMLYNNFKKKSKDEIVVLKNILPTKITTGYYYTDSIVLRVNNIKVKNLKHLIELIEMTKYTNRLMYLKNNKHTLQSYINYYNTKITSLNINTIIHILILTTSGQKVPIVLNKRDVEKYNEEIKKIYSITRDRYVY
The following text describes a protein:
Function:
Structural subunit of tRNA-specific adenosine deaminase, which deaminates adenosine-34 (the first, also called wobble position of the anticodon) to inosine in many tRNAs. Inosine-34 allows the decoding of 3 different nucleotides at the third position of mRNA codons, as inosine is able to pair with U, C, and A.
Miscellaneous:
MISCELLANEOUS: Present with 892 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Nucleus. Peroxisome.
Sequence:
MVKKVNNPLKIDYQNGIIENRLLQIRNFKDVNTPKLINVWSIRIDPRDSKKVIELIRNDFQKNDPVSLRHLKRIRKDIETSTLEVVLCSKEYICDEGEINNKLKSIWVGTKKYELSDDIEVPEFAPSTKELNNAWSVKYWPLIWNGNPNDQILNDYKIDMQEVRNELSRASTLSVKMATAGKQFPMVSVFVDPSRKKDKVVAEDGRNCENSLPIDHSVMVGIRAVGERLREGVDEDANSYLCLDYDVYLTHEPCSMCSMALIHSRVRRVVFLTEMQRTGSLKLTSGDGYCMNDNKQLNSTYEAFQWIGEEYPVGQVDRDVCC
The following text describes a protein:
Function:
Lipolytic acyl hydrolase (LAH).
Domain:
The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
Sequence:
MENVLKKKKLEDITLKETITQVIIPTYDINGLFPRIFTTAEAKMDELKNPTLLEVCMSTSAAPTYLPCHELKNYGDSRNLHLIDGGVAANNPTLTAILNEKREMIIRRQFKTEKNKEEESKMLILSLGTGSFKNVGKYDAADVSKWGLFDWIHKNKTSPIIDIFSDASADMVDIHVGTMFQYDHNLHKNRPDKKNYRRKKNYLRIQAQNLTGELRSVDIATEKNLTDLETVGEELLDKRVSRINLKTGEFEEVEKETKGKALSVKFEGLLVKKGTNRHALIKFAKLLSKERKLRQSS
The following text describes a protein:
Function:
Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Subcellular Localization:
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum. Cytoplasm. Note=Processes and cell bodies of neurons.
Sequence:
MSVPDYMQCAEDHQTLLVVVQPVGIVSEENFFRIYKRISSVSQISVRDSQRALYIRYRHHYPPENSEWGDFQTHRKVVGLITITDCFSAKDWPQIFEKFHVQKEIYGSTLYDSRLFVFGLQGEIAEQPRTDVAFYPSYEDCATVEKRIEDFVESLFIVLESKRLDRATDKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDSLVHYHMSVELLRSVNDFLWLGAALEGLCSASVIYHYPGGTGGKAGARRFPGSALPAEAANRHRPGALTTNGINADTSTEIGRAKNCLSPEDIIEKYKEAISYYSKYKNAGVIELEACVKAVRVLAIQKRSMEASEFLQNAVYINLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSISEPGWRACYKLLLETLPGYSLSLDPQDFNKGTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVTQSLENYTSKCPGTMELLTLPDGLTLPPVPFTKLPIVRRVKLLDLPASLRPQKMKSSLGPSVSAKSPFIYSPIIAHSRGEERSKKIDFQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFESLPAALSLPAESGLYPVTLVGVPQTTGTITVSGYHTTVFGVFSDCLLDSLPGIKTSGSTVEVIPALPRLQISTSLPRSAHSLQPSSGDKISTNVSVQLYNGETQQLVVRLENIGMEPLEKLEVTSKILTTKEKLYGDFLSWKLEDTLAQFPLQPGKVATFTISIKVKLDFSCQENLLQDLSDDGISVSGFPLCSPFRQVVRPRVESKPVNAAEGGRPGEPCHVKTLEAVLNFKYSGGPGHVEGYYRNLALGLHVEVEPSVFFTRVSTLPATSTRQCHLLLDVFNATEHELSVGARSDEELILHAGECQRMAIQVDKFNFESFPESPADKGQFANSKHLEEERQEARGLEINSKLDIHWTIPSLKRTGEASVEGLLNQLVLEHLQLAPLLWDVLVDGQPCDCQAAACRVGDPVRLEVRLTNRSPRSVGPFALSVVPFQDHQNGVHSYDLRHAVSFVGSGTFYLDKVQPSGQAACLGALLFLYTGDFFLHIRFHEDGPSKELPPSWFCLPSVHVRALEAQA
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Cgi121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. Cgi121 is not required for tRNA modification (By similarity).
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MILPLFPETQVHVFVYENVSNCAAIHEQLISQNPIYDYAFLDAATILYKKQVYSAIIRALEDRRDEQMKTKTIHSEVILSLSPKTEISSAFRQFSMTKKSKNIVVVKIDSKLTEEEEFERLDKLVEGNRVEFSDEELQKLIDFKVLKKNYKLDPSTLENPLASILSSIALRGYS
The following text describes a protein:
Function:
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. The QFR enzyme complex binds 2 quinones in or near the membrane; 1 near the [3Fe-4S] cluster (QP is proximal to the [3Fe-4S] cluster, on the cytoplasmic side of the membrane) while QD (the distal cluster) is on the other side of the membrane. It is not clear if both of the quinol-binding sites are functionally relevant.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGVVTI
The following text describes a protein:
Function:
Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
Subcellular Localization:
Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle.
Sequence:
MKLNERSLAFYATCDSPADNTGFLYKKGERHTAYHKRWFVLKGNMLFYFEDRDSREPVGVIILEGCTVELCEATEEFAFAIRFAGARSRTYVLAADSQPAMETWVKALSRASFDYLRLVVRELEQQLEEVRGSEAGGKRAQRCSPGHRRSQPEPVAPPRRDRPVHACPAGSKDNGCAVWSTDPSAWPNGTGPGPRAARLSHDGSPQPPPLPPRRRPSGTSVHSLALESPFSPGTASFGKLHEWYGREIVELRREWLESQGQL
The following text describes a protein:
Function:
May be involved in plant defense.
Subcellular Localization:
Secreted.
Sequence:
MEDKRVAMLVVMMLVMGNMLIEAEAVMSFKLCYGGCLVACALIAPPIKKLFCPFLCIKDCKRRPMLSFEANLNEIDQTGSYCELGCATDRCVSSSSIDDKGYYVNFSGIMWRKFHYAWIHAQKSAPTRTKIAIDFSL
The following text describes a protein:
Function:
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
Sequence:
MIKLHYSQGSVLIYDADDWATLRKTHRILGTLVGNTNTVQTLPLKLLPEEVLLLLDKKLAKLIDSSVNITPEIRNKYEQFENVLLEEEKIMYKNNRKRQLESMIGDIVAAKRKRGDNRSVEEIFTEELEKSSKVNREIMIWPTFLTPLSNDNELIEVSRDEILKNTTELKYSVYKDLWERGYYITTGFKFGADFLVYLGDPIAYHAIFIVHCIDNPDDVMHSSEIVSFGRLATAVKKRAVLATSQNEKISYITINWIDA
The following text describes a protein:
Function:
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
Sequence:
MAQFEQDGKRLHGKKILCVGLCNIDIIQVCDAYPAEDSDQRCQSSRWQRGGNASNNCTVLANLGARCELLASFSDAKMFHFALDDLRERKIAHDHCVYHRGAQVPLSTVWLSLATGSRTIVHSNPDLPELTFEDFQRINLQDYAWIHFEGRRNTSTIVQMIRSIVEWNERPENQSCKVKISVELEKPRHSNLDLLVDGVDVVFVGKDFARFLGHDSAREAIAGLKQLHPGSYIIICPWGERDTVAIDRQDRWFTQPTYPPEVIRDSLGAGDTFVAGCILKLAEEEPPGSLSVVLEFASRVAGQKLAIFGFDGIKRD
The following text describes a protein:
Function:
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system (Probable).
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVGRSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVGLGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRLEMQDLIVSLWQEHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVDIPRPRRLGSVRLAELEAEVLQRVMQRGESETRLRKQG
The following text describes a protein:
Function:
Cleaves the terminal sialic acid (N-acetyl neuraminic acid) from carbohydrate chains in glycoproteins providing free sialic acid which can be used as carbon and energy sources. Sialidases have been suggested to be pathogenic factors in microbial infections.
Sequence:
MTVEKSVVFKAEGEHFTDQKGNTIVGSGSGGTTKYFRIPAMCTTSKGTIVVFADARHNTASDQSFIDTAAARSTDGGKTWNKKIAIYNDRVNSKLSRVMDPTCIVANIQGRETILVMVGKWNNNDKTWGAYRDKAPDTDWDLVLYKSTDDGVTFSKVETNIHDIVTKNGTISAMLGGVGSGLQLNDGKLVFPVQMVRTKNITTVLNTSFIYSTDGITWSLPSGYCEGFGSENNIIEFNASLVNNIRNSGLRRSFETKDFGKTWTEFPPMDKKVDNRNHGVQGSTITIPSGNKLVAAHSSAQNKNNDYTRSDISLYAHNLYSGEVKLIDDFYPKVGNASGAGYSCLSYRKNVDKETLYVVYEANGSIEFQDLSRHLPVIKSYN
The following text describes a protein:
Function:
Ion transporter that can act both as an ion channel and anion exchanger. Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane. Also acts as a DIDS- and thiosulfate- sensitive anion exchanger the exchange of chloride for bicarbonate ions across the cell membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Note=Localization to the cell membrane is inhibited by WNK kinases (WNK1, WNK2, WNK3 or WNK4) in a kinase-independent mechanism.
Sequence:
MNQPRPRYVVDRAAYSLSLFDDEFEKKDRAYPVGEKLRNTFRCSSAKFKAFVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGCIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGIHQMVPGTFAVISILVGNICLQLAPESKFQIFNNVTNETYVDTAAMEAERLHVSATLACLTAVIQMALGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLIFALVSGVFLVLVKELNARYMHKIHFPIPTEMIVVVVATAISGSCKMPKKYHMQIVGEIRQGFPTPVAPMVSQWKGMVGTAFSLAIVGYVINLAMGRTLASKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGSYLYPLPKAVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCVWVVSFLSSFFLSLPYGVAVGVAFSILVVIFQTQFRNGSTLAQVMDTDIYVNPKTYNRAQEIAGVKIVTYCSPLYLANSEIFRQKVIAKTGMDPQKVLLAKQKYLRKQEKRTAIPTQQRKSLFMKTKTVSLQELQQDFESAPSTDPNNNQAPAAEAHISYITFSPDASTAAACELPASTRSPQEASDTLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYEKIGVQIFLVNIHAQVYNDISHGGVFEDGCVQRSHVFPSIHDAVLFAQANAREAPDRNFHGAPGDTEFSLYDSEEEGPSYWDLEQEMFGTMFHTETLTAL
The following text describes a protein:
Function:
Involved in ribosomal large subunit biogenesis. Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's.
Subcellular Localization:
Nucleus.
Sequence:
MGEKLPVVYKRFICSFPDCNATYNKNRKLQAHLCKHTGERPFPCTYEGCEKGFVTLHHLNRHVLSHTGEKPCKCETENCNLAFTTASNMRLHFKRAHSSPAQVYVCYFADCGQQFRKHNQLKIHQYIHTNQQPFKCSHEGCDKCYASPSRLKRHEKTHAGYPCRKDSTCPFVGKTWSDYMKHAAELHSEVTCSICNRTFKRKSFLKEHKKIHREERIVYRCPRENCDRTYTTKFNLKSHILTFHENLRPFVCEHEGCGKTFAMKQSLDRHFNTHDPEKKKMVKPPRPVRSLASRLSGYKPKKSKKKKKPSQTPAMESQEQQPDASKADPLPVLENLTLK
The following text describes a protein:
Function:
Involved in cell wall deposition where it has a role in the localization of mok1.
Subcellular Localization:
Cytoplasm. Note=Localized at the cell poles and septum.
Sequence:
MTSGIYYKGLQCWIPDEQSQWIPGSIKDCRVEGEKAFLTVQDENENETVITVKPDDLNYEGRNGLPFLRSINSDADDLTDLSYLNEPSVLDALSTRYNQLQIYTYSGIVLIAVNPFQRLPNLYTHEIVRAYSEKSRDELDPHLYAIAEDSYKCMNQEHKNQTIIISGESGAGKTVSARYIMRYFASVQALIQSTDSNFHEAPQLTAVENEILATNPIMEAFGNSKTSRNDNSSRFGKYIQILFDGNATIIGAKIQTYLLERSRLVFQPNQERNYHIFYQILAGSSSEQLEKWKLVENSQEFNYLKQGNCSTIEGVNDKEEFKATVDALKTVGIDNDTCECIFSLLAALLHIGNIEVKHSRNDAYIDSKNENLINATSLLGVDPSSLVKWLTKRKIKMASEGILKPLNEFQAVVARDSVAKFLYASLFDWLVATINKALMYSADKSNQTAKSFIGVLDIYGFEHFKKNSFEQFCINYANEKLQQEFYRHVFKLEQEEYAAEGLNWSYIDYQDNQQCISMIESRLGILSLLDEECRMPTNSDENWVSKLNDAFSKPEFKNSYQKSRFGNKEFTIKHYALDVVYCAEGFIDKNRDTISDELLELFTNSDVPFVKDLVLFRLEQTAPPADTKKIKTKPKSNTLGSMFKSSLVSLMSTINETNAHYIRCIKPNEEKEAWKFDNQMVVSQLRACGVLETIKISCAGFPSRWTFDEFVSRYYMLVPSAVRTTESLTFSKAILEKHADPTKYQIGKTKIFFRSGVTPLLESARDKALKHAAHLLYEAFAVNYYRTRFLLSRKRVRSFQAVAHGFLSRRHTEYELLSSNIIKLQSLWRTALKRKEFIQTKNSILKVQSIIRGFLLRQTLEEKTKHDATLIIQSLWLTFKAHKHYKELQYYAVRIQSLWRMKLAKRQLTELKIESTKASHLKQVSYRLESRLFEISKQLDNSEQENNKFRERIAELESHLSNYAEAKLAQERELEQTRVLISDQSQDGELKELLEEKENALIMMEEEMRQVNDANTELLRVNATLKSQLKNYDMIIVEQTSQLKEKNRIIASLTKATKILNSASSIEQSRNSEEKSRRDSSLMEMRTQKEMLVLLMNDGLKHDLDKLTEYAGRTFTTLKTLLLKDNDVEAQKLDHLFLAKLLFIIISQMWKSNLCQESVALVERYCVHTLEYVFQKTSSANERPDIGFWVANTHALLAFVYTKQQAFKHSSAFTLLSTESHESVQTIFEMIESHLSKIFFEWVRQVNNFLKPLIVQAMIITGTNTDAGDENRKLRIKFFEKPKYKITDVIHVLNKVHDSCQAYKVNYEIYNALIRSIYRFINVEAFNSLFIDERGSWKRGTNISYNYHVLKDWCLESGVPEAYLQLEELLQTSKILQFVKDDPNYVARVRDFYALNFLQIKTLLHRYDYADYEAHVPKKTMSELSKNIVAEGINQREQLTYEVLDYRLQDSFEESPSLEKIKIPDDCNVTYLRRIIDLASAEESVEQALITVGNVADNDVQNSSDEENQVPNGIKV
The following text describes a protein:
Function:
Transcription factor, which represses ZNF609 transcription.
Sequence:
MSVNVSTAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKDRQKFEMNNSTNTTTNTTKDCGGPASNGTCSTSALADGLKFASVQPSAPQGNSHKETSKSKVKRAKTSKDANKSLPSAALYGIPEISSTGKRQEVQGRPGEATGMNSALGQSVSGGGSSNPNSNGTSTGTSAATAGAGSCGKSKEEKPGKSHSSRGAKRDKDAARSRKEKHDLLQGHQNGGGGQAPSGGHLYGFGTKSNGSGASPFHCGGAGSGSVGAAGEVSKTAPDSTLMGNSMLVKKEEEEEESHRRIKKLKTEKVDPLFTVPAPPPPIASSLAPQIPPSYFPPSSSNIAAPVEQLLVRTRSVGVNTCEVGVVTEPECLGPCEPGTSVNLEGIVWHETEEGVLVVNVTWRNKTYVGTLLDCTKHDWAPPRFCESPTSDLEMRGGRGRGKRARSAAAAPGSEVSFTESRGLQSKNRGGANGKGRRGSLNASGRRTPPNCAAEDIKASPSSTNKRKNKPPMELDLNSSSEDSKPGKRVRTNSRSTPTTPQGKPETTFLDQGCSSPVLIDCPHPNCNKKYKHINGLRYHQAHAHLDPENKLEFEPDSEDKISDCEEALSNVALECNESSTSVSSYDQTKAPGSPGAGNPPGTPKGKREHVSNGPGPIIGSKTGKNSGKKRGLNNELNNLPVISNMTAALDICSATDSNLTAEMPKLEAEGLIDKKSLGDKEKGKKANNCKMDKNLSKLKSARPIAPAPAPTPPQLIAIPTAAFTSTTTGTIPGLPSLTTTVVQATPKSPPLKPIQPKPTIMGEPITVNPALVSLKDRKKKEKRKLKDKEGKETGGPKMDAKLGKLEEAKAASKDLSGHFLKDHLGKSEGLANGLSESQESRMASIKAEADKVYTFTDNAPSPSIGSASRMECSTLVNGQAPMAPLHVLTQNGAESAAAKTSSPAYSDISDAADDGGSDSRSEGMRSKASSPSDTFSNKDGVVKGHPSTSAQPSQLKESHSPYYHGYEPYYSPSYMHPGQVGAPAAGNGGSTQGMKIKKESEEDAEKKDKAEQLESKKVDHTSAPLQPQHQSVITQRHPALAQSLYYGQYAYGLYMDQKSLMATSPAYRQQYEKYYEDQRLAEQKMAQSGRGDCERKAELPLKELGKEDNKQKNMPSATISKAPSTPEPNKNHSKLGPSVPNKTEETGKSQLLSSHQQQLQADSFKAKQMENHQLIKEAVEMKSVMDSMKQTGVDPTSRFKQDPESRTWHHYVYQPKYLDQQKPEELDREKKLKEDSPRKTPNKESGVSSLPVSLTNIKEEPKEGKRPDSQSVEENKLKNDDRKTPVNWKDSRGTRVAVSSPMSQHQSYIQYLHAYPYPQMYDPSHPAYRAVSPVLMHSYPGAYLSPGFHYPVYGKMSGREEAEKVNTSPSINTKTASEAKALDLLQHHANQYRSKSPAPVEKASTEREREAERERDRHSPFSQRHLHTHHHTHVGMGYPLIPGQYDPFQGLTSAALVASQQVAAQASASGMFPAQRRE
The following text describes a protein:
Function:
Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond.
Sequence:
MSAPDGSGPEPVVMLHGDLDLTIHEARGLPNMDVLSTLLRRLCLFRPPRRSSRPLPPRSVSASDEEDNPSTSSSHHHRHHHLHRRRPRRPKQPHGPRHLLPTSDPYAVLLIPPATVLARTHVVRNADRPVWSARIRVPLAHAASRIVFNVRDADPFGSDLIAAASLPASDLLSGTPIVSRWLDLLRPDGRGGKPKPDSAIRISASFTPAYSSLSRGGGIIPAYFPERRGCEVKLYQDAHGGAAKGGCWEDVCMAVLGAQSLVYVAGWAVGARVRLARKGEMSPEMEEKAAEVMALSSAAGGGGGDEAASPELGEMTLGDLLKYKSQEGVRVCLLVWDDKTSHDKFFLKTGGVMGTGDEDTKKFFKHSTVMCVLSPRYPSSKLSMAKQKLVGTLYTHHQKLVLVDTPASDTTRRVTAFLGGLDLAAGRYDTPAHRLFAGLGTVFRGDVRNPTLGLGSGSGGGETAGPRMPWHDLHCRVDGAAAYDVLANFEQRWRKATRLNDALGRKRWMDDALLRLHRIPWILSPNNVAGAGEDDPALRVFPEDDDPRQWHAQIFRSIDSGSVKGFPRSWETQEMAERNLQCDKNVAVEASIHAAYVAAIRRARRFVYIENQYFIGSSYAWPESYYRSSAAGNLVPMEIALKVASKIYAGEDFAAYVVLPMFPEGGSPASGPAQEILFWQAQTMRAMYNIVADAIATAAGSSKLAGSRRAHPQDYLNFYCLGNREPLGGGDNGASRARPAPETTRWGTTTSSSSAPSASVATATALESARRNRRFMVYVHSKGMIVDDEYVLLGSANINQRSLAGSRDTEIAVGAYQPHHSGNSPRGEVYRYRKSLWEEHLGAAAMAAAAVESPEKEECVRMVNRTARENWERYAAEEATAEMPMRGHLMRYPVEVGADGSVGPLQGHEFFPDVGGRVLGSTNKLPDDLTM
The following text describes a protein:
Function:
Involved in the degradation of plant cell wall polysaccharides. Catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with equal efficiency, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc). Does not bind cellulose, cellohexaose and beta-glucan.
Subcellular Localization:
Cell membrane; Lipid-anchor.
Sequence:
MKLLFPILLLTGSYFLSACNNTQSLMSSTHTIAASDPHIQVMGRTHINDDASLTFGYPGVSLSTIVAGSRLTAEMQSSNGNSWIDVIIDNHPPTSIKLDAQQQTVELFHFPNSGEHRVEIIHRSENWHGQVTLKQLTLTGTQFLPAPVLPQRKILVLGDSVTCGEAIDRVAGEDKNTRWWNARESYGMLTAKALDAQVQLVCWGGRGLIRSWNGKTDDANLPDFYQFTLGDTGQAPQWDHHRYQPDLIISAIGTNDFSPGIPDRATYINTYTRFVRTLLDNHPQATIVLTEGAILNGDKKAALVSYIGETRQQLHSNRVFYASSSHHPGDNSDAHPTKDQHAAMARELTPQLRQIMDW
The following text describes a protein:
Function:
General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
Subcellular Localization:
Nucleus.
Sequence:
MTDRRMSGVAGGGGVTGSPAPAPGRDWAGRGWGAVPLQSTSLPPLCQSPACGRACGHGSGAMPKSKELVSSSSSGSDSDSEVDKKAKRKKPTPEKPVKKQKTGESSKGAASSKQSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDQEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL
The following text describes a protein:
Function:
Catalyzes alpha-1,3 glycosidic linkages of N-glycans. Plays a role in neuronal development by promoting ventral nerve cord formation, possibly by promoting interactions between migrating cells and the extracellular matrix or by promoting neural activity.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Sequence:
MRRPKISLKKYFYLTLICALLLIFGFSLKEREIWKTLSPRSSQITTQQQQHQHLHQLQSMDEEHPMATSSTPPPIAATLLPEVADNLVEEPEQTVLEEEESEADRLQEPPAEKAWFFKNGEYYPKPAKTYSNRKARKRHAPRLLPHQDPYSDRIINQLMYVPHNYEEIKSSGKLKTILLYNGLGPWNVKKGRDVFLKAKCPVDTCELTANRDLASTADMILYKDHYIPTGIRRPSNSKQVSMLYYLECPYHTQNVKVPDAINWTATYRRDSTIVAPYEKWQYYDTKVQQQEQDINYSVNKTKKVAWFVSNCGARNGRLQYAHELQKYIEVDIYGACGNFKCSRSTADKCFEILDNDYKFYLAFENSNCKDYITEKFFVNALNRRVLPIVMGARPEDYEVSAPRRSYIHVDEFSSPKELAEYLRILDHDDELYNSYFKWKGTGEFINTYYWCRVCATLHNEEQLRKPRWYTDLNDWWRGPGVCTTRSWRNFKARKDVISDSSDD
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Its function in the WMM complex is unknown.
Subcellular Localization:
Nucleus speckle. Nucleus, nucleoplasm.
Sequence:
MKAATTDPRDQELELDNELQGTNSSGSLGGLDVRRRIPIKLISKQANKVKPAPRTQRTVSRMPAKAAQGDEEGFDYNEEQRYDCKGGELFGNQRRFPGHLFWDFKINILGEKDDTPVHFCDKCGLPIKVYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPDRFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSSSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRMQGPPSQTPLPGPHHPDQTRYRPYYQ
The following text describes a protein:
Function:
GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
Subcellular Localization:
Cytoplasm. Note=May associate with membranes.
Sequence:
MEEVLQRAVLVGVNVGNEDDFAYSMEELTNLAEACDVEVIGQVTQNLQRVNPSHYIGKGKIEEVAAYVQEIDANMVIFNDELSPSQIRNLEEDLDCKVIDRTILILDIFAQRAKTKEAQLQVEVAHLQYMMPRLIGLRESLGRQSGGVGTKNKGVGEKKLELDRRKIEEQISVLNKDLEALVAQRQTQRKQRKKNEIPVVALVGYTNAGKSTTMNAMLEIYNGTEEKQVFEKDMLFATLETSVRNIDLPDNKSFLLTDTVGFVSKLPHHLVKAFRSTLEEVAEADLLIHVVDYANPNYEQLIDITNETLKKIGVENIPTIYAYNKSDMVDVEIPKVQEDRVYLSAKKHVGIEELVEMIRSHIYKEYTKCEMLIPYDQGQVVSYFNNHAHVLSTSYENEGTKLQIECKTSDYEKYKHFAI
The following text describes a protein:
Function:
Microprotein involved in mitochondrial respiratory chain complex III (ubiquinol-cytochrome c oxidoreductase) and complex IV (mitochondrial cytochrome c oxidase complex) assembly. Required for the formation of mitochondrial supercomplexes (SCs). Also required for the activation of the NLRP3 inflammasome.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Mitochondrion intermembrane space.
Sequence:
MLQFLLGFTLGNVVGMYLAQNYEMPNLAKKLEEIKKDLEAKKKPPSS
The following text describes a protein:
Function:
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MRSSPHWHVCLAPRKRAQCVLGAEKQASSFARPIRPKKPTEMDPLRAKATPAGNSQTESAPSQLPLKPLVVVGSINADIYVEVDRLPKPGETLAAGSGYTLPGGKGANQAACAAKLGYPTYFVGQVGEDGQAIMLRDELQQCGVRTDHLRSVSGPSGQAIVMLQPGGQNSIIIVGGANTAWPELSPGQRLTSEARSLIRGAGAVLLQREVPEEINLEAAAVAESAGVTVVLDCGGADGPVSEALLQKVSVISPNETELARLTGRPTDTPDEVNGAAGLLKRQQHLSVLVKLGEQGSLLFPAVGEPLRQPAVPAPSVVDTTGAGDTFTAAYAVATLEGRSSKDALAFAALCASLCVRSKGAMPSMPDRATVDKELKATQAVA
The following text describes a protein:
Function:
Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
Sequence:
MIGFLTTLRTVNERNFLGELNSISMQKSSSSEGVSHVRRSISLNKLKNQFADAAEAEHFTNESDSEKYNNLWDYCSLYLSKDVETIKQQIANHIEYTLACQRFDFKTKSLFTATAISLRERMTEYWNDTHQYFREIQTKRMYYLSIEYLIGRSLMNAICNLGLENEYRDVVSQFGSSLEELYEYENDAALGSGGLGRLAACFLDSLATMNLPAWGYGIRYQYVADIVNNDKTIDNMLKIVFIPNYSVSLAEVIIPANDINEQISTAGYEASGTSCMKFCMNGGLIIGTWDGANVEIAEEIGEENMFMFGAKKNEVELIRQQGTSYIDERLYDVLKAISGGMFGAADWFNKLIGQFWGGNDYYLVAHDFASYLEAQMKVDATWKKPQEWNHKCVMCVSKMGKFSSDRSMKEYAANVWNIHPCPLPETDMNDMMDIAKKQLLPEKK