lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MFEVSFTLVALLLLCIQPAIAAPPLNSNCTERCGNVNITYPFGMGKKECYLNEWFEIECNKSVYPHRPFLRRIKMEVLDISAGGSATVISPIVSSNCSGWEGDEPINLTGSPFYISNSNSFISVGCNTRALLMDEPLLRVGCDSSACNGTGCCKITVPSTVQVFNPILNQHTGGCELAFLAVDGGLLYRPEVSKFPMVLDWTINSTQTKAIDRETANCSSYLYGNGPEFQCYCNDGYEGNPYIGCTDTDECKSPNYHFCRRFTKCMNTKGSYKCVPDPKWIIIIVLCGVIGVLAIPLGCWRLYKVLRKLRDIQLKKKFFKRNGGLLLKQQLNSSDGSVQKTKIFSSKELEKATDRFSENRILGQGGQGTVYKGMLTDGRIVAIKKSKLLDEEKLQEFINEVVILSQVNHRNVVRLLGCCLETEVPLLVYEFIPNGSLFQYLHDQSEEAPLPWDMRLRIAGEVAGALAYLHSAASIPIYHRDIKSTNVLLDEKNRAKVSDFGTSRSITIDQTHLTTRVQGTFGYLDPEYYQTSQFTDKSDVYSFGVVLVELLSGKKPIYSRSSEEIMSLAMHFVVLMEENRLFDIIDARIVEHCAEEEITEVANLAKRCLNLNGKKRPTMKEVAAELDGIQTSRSKLNIVKKNNEEIEDNLSDDDSITESYETQETISDGIAIAV
The following text describes a protein:
Function:
Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSSDSGPLHRRTIPISVHIFSGFFYAPFYAPQLTQFIVTITMYSTYQRPAGYQPRQQPQGEEDRRPAHRRTVDHGSAFGKWHLDRLSGRTIQPANMRSEQSYIVDLLPPSAYTNINGSLRSTNPHITSVAATPAKFIQVALNKVRHPVYSATWTPDGRRLLTGSMSGEFTLWNGMTFNFESIMQAHESGVRSLKYSHSGEWLLSGDHEGNVKFWQPSLNCVNVIDKAHRESIRELAFAPSDHKFVTGSDDGLLKIWDFHESSNAESVLKGHGWDVKSVDWHSELGLIVSGSKDNLIKLWDPRSAKNVNTFHGFKNTVMKTTFQPTGTKRLLAAGCRDRTCRILDLRMLNSGSSEAGPTAGTDMPTRGDRSMAVLRGHDSDVFSLTWHPTHANVVTSGTKTGSIYTFNVDTTPAGGAYGPDSGILPVNTIPSAHDYCVSTLDYHPEGHVLCSGGLDRMTRFWARPRPGDPTSFRDKYYEPKEEGVSVKTLPGVNNATSRAGMARVEHVSTQHFNTAQPEVTDDEPVSIPGFAR
The following text describes a protein:
Function:
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.
Sequence:
MSAPGYPGHFPYPAPGGGYGDPNQAPPPGFNMGYNQGPPVMYQPGQGPEYGAPLVGAAPVPLVPIGIPPGLEYLAQIDQILIHQKVELLEAFIGFETNNQYEIKNNLGQKIYTAKEKNDCCTRNCCGALRSFDMKIKDNTDREVIRLIRPFRCVSCCCPCCLQEMEVQAPPGTTVGYVKQDWHPFLPKFSIQGANKETLMRLEGPCFACNCCGDVSFELKGKDETPIGRITKQWSGLLKEVFTDTDNFGIQFPLDLDVKMKAVLMGACFLIDFMFFEKVGEANQRSSVFS
The following text describes a protein:
Function:
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
Sequence:
MDYEEQLDRAMDEKPDVTGSETRFEVPDPNVRKEGNVTVYENFQATLDALSRTQDHVLKFLQNEVGTSASIDESGRARLTGEFGQRRVSDTLDAYVETYVTCPECGLPDTNLETDGDTIQLHCEACGARSTV
The following text describes a protein:
Function:
Catalytic subunit of N-terminal acetyltransferase complexes which display alpha (N-terminal) acetyltransferase activity (By similarity). Acetylates amino termini that are devoid of initiator methionine (By similarity). The alpha (N-terminal) acetyltransferase activity may be important for vascular, hematopoietic and neuronal growth and development (By similarity). Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation (By similarity). Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration (By similarity). Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development (By similarity). Acetylates HSPA1A and HSPA1B at 'Lys-77' which enhances its chaperone activity and leads to preferential binding to co-chaperone HOPX (By similarity). Acetylates HIST1H4A. Acts as a negative regulator of sister chromatid cohesion during mitosis (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Note=Also present in the free cytosolic and cytoskeleton-bound polysomes.
Sequence:
MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGSIENKMEGKGNSLPSSGEACREEKGLVAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
The following text describes a protein:
Function:
May be involved in the synthesis of NodRm-1, a sulfated N-acyl-beta-1,4-tetrasaccharide of N-acetylglucosamine which initiates a series of events in the host plant species leading eventually to nodulation.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MDLLATTSAAAVSSYALLSTIYKSVQALYAQPAINSSLDNLGQAEVVVPAVDVIVPCFNENPNTLAECLESIASQDYAGKMQVYVVDDGSANRDVVAPVHRIYASDPRFSFILLANNVGKRKAQIAAIRSSSGDLVLNVDSDTILAADVVTKLVLKMHDPGIGAAMGQLIASNRNQTWLTRLIDMEYWLACNEERAAQARFGAVMCCCGPCAMYRRSALALLLDQYEAQFFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPHSLRPYLRQQLRWARSTFRDTFLAWRLLPELDGYLTLDVIGQNLGPLLLAISSLAALAQLLIDGSIPWWTGLTIAAMTTVRCCVAALRARELRFIGFSLHTPINICLLLPLKAYALCTLSNSDWLSRKVTDMPTEEGKQPVILHPNAGRSPAGVGGRLLLFVRRRYRSLHRAWRRRRVFPVAIVRLSTNKWSADDSGRKPSVIRARVGCRRPVAPRH
The following text describes a protein:
Function:
Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.
Sequence:
MDLDAVTKQSVLHAKPDGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEEDNGVKLVDPLGEMLAASWEEHATCLANAEEQHLPRVLVDISEKAAVDLHQDAFVVIGRDTRPSSERLSQSVIDGVTVLGGQFYDYGLLTTPQLHYMVFCRNSNGQYGKATVEGYYQKLSSAFVELTKQAFCRGDDHRTLKVDCANGIGALKLAEMKHYFSPGLSVQLFNDGTKGKLNHLCGADFVKSHQKPPQGIEMRANERCCSFDGDADRIVYYYHDADGQFHLIDGDKIATLISSFLKELLLEIGDGLSLGVVQTAYANGSSTRYLEEVMKVLFSKAAETKIKQLAKESEDEKRKAAKMLENIIDLFNQTIGDAISDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVKVADRQVISTTDAERQVVKPPGLQEAINDLVKKYRLSRAFVRPSGTEDIVRVYAEADSQENTDSLAYEVSLAVFQLAGGIGERPQRGF
The following text describes a protein:
Function:
Sperm-specific solute carrier involved in intracellular pH regulation of spermatozoa. Required for sperm motility and fertility. Involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (sAC).
Subcellular Localization:
Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.
Sequence:
TAGIFFFSGCHKPWVVSLSIISSIQNYHLLFYMEYKKFNHPFCVAKKSVIFYNASHFQLTILSTFCYQLPFVKHIAEIDPVLFLHLFTPVIIFTASFEMDFYIFRKSFWQVLVLAVPGFLMNCGFLGWLTFKINKYNWSWDDSMLFGIILSTTDPILSVAAVKNIGLSKIVTNLIKGESLFNDATTVIIFELYRDLVHQSHQETSNFNILKEIFVQLILKFFASIAFGFLSSKLVSYWLAHIFNDGIIEVILSFSMAYVIFFLAEWFGMSGVISLCMLGLLLDSVSFSPGMDAFLYKFWAMLTFLAHIMIYLIMGIVIAQKTFPYINTRGFFSVITVYLSLNLVRALVILTLSPFLSRLGYGFNWRWGAVLVWSGMRGTFTLNMALALSQTPSITAADLQVKTMIFIFVLQNACLLIDCALNKWVLHLCLCNITLPKRMAMHNAVQRIRQMEANAFSMLKLDRFLADANWTMAEDSMTIEYPYKLDTEEIRQLSKTLKCPDCDADIAFERSPQQIADIMEEARLRLLTAQIASYQKQYNSGMLNQEAAQTLIGAAESYVDIEGKFMNIHEVKTYWESKGMLVTMKKWLSDWVYNVKDETTKAPKNKFLRLCHQIVFMEEFEYISTMITYLNSVPIILNFITSVNAEYLPQLKMCNYYFLCLYIGEAALKALAMGRTYIYYHWNQFDLIVIVVGIIDVMIINLFKNMTPSYPMINTIRIFRFGRLLRVFRLFKLTLPTLIFVLDKQINKQLTFRYDIAKGYVQGEEDIKRLIEQISGHEKVYIEITKILEKNKQEAMKELGLMQRDYPEIVTAVKTRQAVQTVLNTASETLKFMISGGIVDRNEGAELHKVILVKKKHLAKLPPTIAPPTAQQLLHNVMWLQDNKNQIEFIQKKAKILYYDYGDIICEEGELPQGIHLIVSGMIKVRSNVMKEGAKKTTHGHTAASSYTDYMVTGAIIGELNCLTKQEMEYAVSCETAVQTCFISIDDLLEAFDRFLEPPSLEYKIWLKIALDIALKTYKENLPNQDWSYKLCAQYSNMYVVDVLNHTKCDIYDEAMDDVILVHGTVQDCQLGQRYCAPCILPKTCHQSPYFADFHFSRVVLERNPRNK
The following text describes a protein:
Function:
Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
Sequence:
MVMAEGAAVLRRNRPGTKAQDFYNWPDESFEEMDSTLAVQQYIQQNIRSDCSNIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDKYENETFLCHRFTRFVMKYNLMSKDNLIVPILEEEVQSAASGESEA
The following text describes a protein:
Function:
Plays a continuous role in plant development probably in the structural organization of compartments (By similarity). Seems to be involved in resistance to oxidative stresses mediated by thiol-oxidizing agents such as diamide.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MMGQEAAPTGPPNRELYALLNLSPEASDEEIRKAYRQWAQVYHPDKIQSPQMKEVATENFQRICEAYEILSDETKRLIYDLYGMEGLNSGLELGPRLSKADEIKEELERIKRRNEEAKKMAHFQPTGSILFNLSVPHFLVGDGIMRGMVMASQVQSQLSKDDAIAIGGNLAANEKSGGGVATAILRRQISPVSSIEFVASTGLQSLIGVQTTRQLTIHSTATINISKSLSDGSINLTNTWTRQLSETSSGNIELALGMRSAITVGWKKRDENVSAAGDFKIESGGLGASARYTRKLSSKSHGRIVGRIGSNALEIELGGGRQISEFSTVRMMYTVGLKGIFWKVELHRGSQKLIVPILLSAHLAPVFATGAFIVPTSLYFLLKKFVVKPYLLKREKQKALENMEKTWGQVGEARARAEKAQQLLQTVATRKKNRQVETDGLIVTKALYGDPKAIERRNEGVEGLDSGVIDVTVPMNFLVSDSGQLKLHEGVKKSGIMGFCDPCPGQPKQLYIAYTYHSQPFEVIVGDYEELSIPQEGQ
The following text describes a protein:
Function:
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence.
Subcellular Localization:
Nucleus.
Sequence:
MFFHSGVAVSHCNQICCQVSNAGFSTQNCPLRIYPLEWYRRASLNCAAHERLGSPKENHSLDDACYSGTASDRDSPGISEPTEGNERKQEENTADGKEDDTLHTFHGLPDQETPEQKSARKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAADLEAANLSHSAQRIVRVPILYHENSTPPALGFSVPQVSPPLVGFSSTVNYPVTAFPSSMSFIRSQMTGFV
The following text describes a protein:
Function:
Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity).
Subcellular Localization:
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Sequence:
MGQYTVSTRKNVRILLVGDAGVGKTSLILSLVSEEYPEEVPPRAEEITIPANVTPEQVPTSIVDFSSVEQTEETLGLEINKAHVVCIVYSVDDDDSLDRITSHWLPLIRSKCNATLEGDAETEAETEAAGEGLRKPIVLVGNKIDLIDYSTMDSVLAIMEDFPEIESCVECSAKTLHNISEMFYYAQKAVLHPTSPLYIMEDQELTPACKKSLVRIFKICDTDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVIQKNVPDGIYNDAVTLKGFLFLHCLFIQRGRNETTWAVLRRFGYNDQLEMCQEYLRPPLKIPPGSSTELSHRGQKFLISVFERYDRDCDGALSPEEHKMLFSVCPSSPWSYSTDIRKSCPINDKGWVTLHGWLCRWTLMTLIDVVKTMEYLAYLGFNVHENDSLLAAIHVTRERRIDLAKRQSSRSVYKCHVIGPNGSGKTGLCRGFLVDEMQKLIGKEFKTNVVHCINSVQVYGQEKHLILRDIDVRHALDPLQPQEVNCDVACLVYDSSNPRSFEYVARIYIKYYAESKIPVMIVGTKCDMDERRQDYLMQPAEFCAKYKLLPPHLFSLRTNKKELYTKLATMAAFPHLRHFGLLTEDSKLLWKAGLGLAAATMLGFIVLKTLSAAGSHSR
The following text describes a protein:
Function:
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTPPPITTPPSTATTQIHHSIRPWLTDFLSLSSLSLPLSFPELSLRIQRNLYTYRTNYLFISFLIFLLTLIPHPITFILFIAIIIAWIYLIFYTNEPLFVLDFEIGHRLIVILLSVVTVGALAVTSVWWNVFLSVLISALVVLAHASLRTPDDVEESPYGALLSVVDDDVDAGPYTLVSDFELFHGTRTLLSSSASVSVMVRQNDCGKWGRAIV
The following text describes a protein:
Function:
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subcellular Localization:
Mitochondrion.
Sequence:
MSLLREAEKCIANQRSHAALNAFITTVQHLGPLREQVRDAELRRESGRSKSEVDGRLIAFKDNICTRDFPTTCASGILAKFTSPFNATVVEQLSEAGAIVAGKTNLDEFGMGSHCLNSCFGPVKNQRQCQEGRILSAGGSSGGSAVSVATDQCYAALGTDTGGSVRLPAAYTGTVGFKPSYGLVSRWGVVAYANSLDTVGILAKNASTARDVFRIVNRHDPRDPTNLSPRSRSRIASHLQQPALLSRMTSSLRIGVPIEYNISELSPSVRRAWALSIAFLREQGHTIHPVSLPTTKLALSAYYVLAPAEASSNLAKYDGIRYGSRCNSPDSGGQPESYLYAKTRGDGFGLEVKRRILLGAFSLSADAINNYFIQAQRVRRLVQHDFNAVFRAEQPISPSRQKGDTELKSKQAEVDVLICPTAPSCPPQLADLVETDSIFSSLNAYTNDVFTVPASLAGLPAASVPVRVNCRDEGSSDADLAGIQIIGQYGDDELVLKVSESLEGKIF
The following text describes a protein:
Function:
Intrinsically disordered protein which may negatively regulate mTOR signaling pathway by stabilizing the mTOR complex component DEPTOR. Negatively regulates angiogenesis (By similarity). Negatively regulates cell growth (By similarity). Negatively regulates neurite outgrowth in hippocampal neurons.
Subcellular Localization:
Cell membrane; Single-pass type IV membrane protein.
Sequence:
MEANQEASLFLVKILEELDSKQNTVSYQDLCKSLCAQFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCSVNNQQSKKIMVAADIVTIFNLIQMNGGTAKEKLPTSCHKVRKEEASFESCRSDAEVCSPTVCEPLNCELSERPFSRGYPTRQSSKCRKMDCKECPQFVPASEPNFLLGVSKEVKNRAASLDRLQALSPYSVASPQPCEMQRTYFPMNIENESISDQDSLPIGQGIKETFISSEEPFMVQSCVQKRNIFKEDFHNLMTVSPSLVGTTNKAEEDHGEPRSQKELHKPPFFNHSFEMPYHSQYLNPVYSPIPDKRRAKHESLDDLQASTYFGPTPVMGTQDTRRCPGRPSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSGNQTPNFSGPDRHPVYLVPKDQQKVLPAGYAVKPNGLKSKEIPSPVDLEKHEAVKKFKDKSISCTSGQHSSDTSSVGTQTEQHVLDPPKCKDLCSAGQAKYSDRHAMKHSDDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHNLAKITNGVSGSKGDKCNRPENVHHSEEELKSSVCKLVLRIGEIERKLESLAGVREEISQVLGKLNKLDQKIQQPEKVNVQIDLNSLTSEAPSDDSASPRVFHAHSGSHGPKLENSPDWCCSDVSGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYTNRMSLNEEEIKDAGPANNKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHPYPSSLKAHMKSNPLYTDMRLTELAEVKRGQPSWNIEEYARNTGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALITAAACTVILVIVVPICTMKS
The following text describes a protein:
Function:
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region.
Sequence:
MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIFVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGPQGEGEPSGIPIAMVLVPVFALTMVAAWAFMRYRQRL
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MDLSGTQGELPMAMHAGGGGGGSPYLGLHHGHHEQQHNHGANGRHMSPPDVVAEEAKNRQLAVVPVSGAGGGGGAGVRYRECLKNHAAAIGGSATDGCGEFMPAGEEGSLDALRCSACGCHRNFHRKEPPGGGGGGDARQLHGHGHHHHHHHPLSPLSPLAAAHHHRGLLVAALPPAPTRMVMPLSAMHHQQQHHNSSASAESDDAHNAPGHAHGQQQGPPARKRFRTKFTAEQKARMLGFAEEAGWRLQKLDDAAVQRFCQEVGVKRRVLKVWMHNNKHTLARRGHDGVGDPQQQGPHGGQLGMPLPEPGGPGRSPSRSPPPQLRLE
The following text describes a protein:
Function:
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid-expressed genes, thereby regulating the synthesis and secretion of alkaline protease XPR2 and acidic protease AXP1 depending on ambient pH. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for mating and sporulation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MASYPYLAQSQPPQQQQQQQQQPQQQSQQLPTTAPSAAPQVNNTTANKPLYPASPNSPISPSDYSANMNVGGDSVDMLLSSVSAHHRSSDAGQSDMGSISPSTAHTTPDATTYKTSDEEDATGKITTPRSEGSPNTNGSGSDGENLVCKWGPCGKTFGSAEKLYAHLCDAHVGRKCTHNLSLVCNWDNCGIVTVKRDHITSHIRVHVPLKPYKCDFCTKSFKRPQDLKKHVKTHADDNEQAHNAYAKPHMQHTHQQQQQQQRYMQYPTYASGYEYPYYRYSQPQVQVPMVPSYAAVGHMPTPPMHPHAPIDRKRQWDTTSDFFDDIKRARVTPNYSSDIASRLSTIEQYIGIQGQQQQASPTPQTATTTSATPAPAAPHQATPPQQQLPSFKQGDYQETDQFLNQLGSNIYGNIKSVDPQYEAPAEFHLPHPMGYRYAFSHAPAPHGAAPVAPQVAPPAHPGVHGVSAPHYPDLSYSRSTVPQLSSRFEDVRQMSVGVTQRAARTTNVEESDDDDELVEGFGKMAIADSKAMQVAQMKKHLEVVSYLRRVLQEARETESGEAEDTAANKDTSASKSSLYPTIKAC
The following text describes a protein:
Function:
Catalyzes the reversible conversion of 2-phosphoglycerate (2-PG) into phosphoenolpyruvate (PEP). It is essential for the degradation of carbohydrates via glycolysis.
Subcellular Localization:
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface.
Sequence:
MAKITSIEGRILYNSRGSKTIEVDVESEGKFVGRVCAPSGASVGKYEAVSFRNGRPEDSLQVLKENSQKFIGLESSDLKGIHDTLKSFDNSSNYSEIGGALAFAVTIASMESASKALDQPLFKTLSNESSFKFPFPLGNILGGGAHAGPGTPDIQEILICATGAKTIEESIETNLAVHKELRSVLEKEDPNFTNGRGDEGGWAPKLENQKALEVSAMACENLGFTLGKEVSLGVDFASSTQWNEEKSKYVYDRAGFENTTSEQIDFAADIIEKFKLIYAEDAVHEEAFEDMSELTAKFPNTLITGDDLTVTNKGILSKAIDKKSCNAAILKVNQAGSLYDALEFANLANENNIRLITSHRSGESTDSQISHIGLATKSKMLKVGVVGGERVAKLNELLRLSEHDLIRGMAEV
The following text describes a protein:
Function:
Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKNGGPNHHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTANTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIPQVSPMRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
The following text describes a protein:
Function:
Component of an histone acetyltransferase complex.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MARNFTLIHELDSTSYEVMRKVRLETDDFMSNVVSFTKEERKARLIKISALFKSCLKHGHDKVELAVQTYDMVDRHIRRLDDDLMKFEEEQMTGPKVLPSHSQPREDPRQYRSEKLTRETGSSRLSRRAQSGIGQVALPEVDTPTKKRRVPDDERPPLNESPVATPVSSTPQKPIVAPVPKPLVSAVSKKSSIKSKKTSTNVTPVPTPPMEVKIGKELVPVDLEIDPNEPTYCICKQVSFGEMIACDNDDCPIEWFHYTCVGLTDPVKGKWFCPICVEKRKI
The following text describes a protein:
Function:
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
Subcellular Localization:
Cytoplasm.
Sequence:
MLENLIKDFKEIFKYSGEVERFFSPGRVNLIGEHTDYNGGFVFPCALDFGTYAVVKKREDKTFKMYSKNFENLGIIEFNLDNLIYDKKDDWANYPKGVIKTFLDRNYKIDSGFDVLFFGNIPNGAGLSSSASIEVLTAVILKDLFKLDVDIIEMVKMCQVAENKFIGVNSGIMDQFAVGMGKKDNAILLDCNTLKYEYVPVKLVNMSIVIANTNKKRGLADSKYNERRTSCEEAVKVLNNNEVNIKYLGELTVTEFEKVKHYITDEEQLKRATHAVTENERAKIAVEFLKKDDIAEFGKLMNKSHTSLRDDYEVTGLELDSLVEAAWEEKGTVGSRMTGAGFGGCTVSIVENDYVDSFIKNVGKKYKEKTGLEASFYIANIGDGAGKVK
The following text describes a protein:
Function:
May be involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity.
Sequence:
MSQVSAEFIPTRIAILTVSSRRGEEDDTSGHYLRDSAQEAGHEVVAKAIVKENRYAIRAQVSAWIASDEVQVVLITGGTGLTEGDQAPEALLPLFDREVEGFGEVFRMLSFEEIGTATLQSRAVAGVANNTLIFAMPGSTKACRTAWENIIAPQLDARTRPCNFHPHLKK
The following text describes a protein:
Function:
Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. Blocks the activity of the SRCAP chromatin remodeling complex by interacting with SRCAP complex member ZNHIT1 and inhibiting its interaction with the complex. This prevents the deposition of histone variant H2AZ1/H2A.Z at the nucleosomes of key lymphoid fate regulator genes which suppresses their expression and restricts lymphoid lineage commitment.
Sequence:
MAHITINQYLQQLPSPEDKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPIMYAVALDLRIFANNADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIDDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSRAQRVTYRYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTVELLRKYHLMQFAEVTKAVSEGNLLLLNEALTKHETFFIRCGIFLILEKLKIITYRNLFKKVYLLLRTHQLSLDAFLVALKFMQLEDVDIDEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLSTVC
The following text describes a protein:
Function:
Probably involved in the defense reaction of plants against pathogens.
Sequence:
MGSFSQLCLLGLTLIMGSHVAHAQDSPADYVNAHNKARSAITTIKIPNIVWDNDIAAFAQNYANQRKDCKQIPSGSGGRYGEYLGENIAVSTGYISGAEAVKLWVDEEPYFNHYANSCIDGHECHHYTQVVWEKSLRVGCGKVKCDNGGSFVTCNYDPPGNIAGQLPY
The following text describes a protein:
Function:
Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3.
Miscellaneous:
MISCELLANEOUS: [Isoform 3]: May result from the retention of an intron in the cDNA.
Subcellular Localization:
Golgi apparatus.
Sequence:
MACAGLLTVCLLRPPAPQPQPQTPRHPQLAPDPGPAGHTLFQDVFRRADKNDDGKLSFEEFQNYFADGVLSLGELQELFSGIDGHLTDNLETEKLCDYFSEHLGVYRPVLAALESLNRAVLAAMDATKLEYERASKVDQFVTRFLLRETVSQLQALQSSLEGASDTLEAQAHGWRSDAESVEAQSRLCGSRRAGRRALRSVSRSSTWSPGSSDTGRSSEAEMQWRLQVNRLQELIDQLECKVRAVGPGPHKGGPSWYPPEPGPCWRPGPHSVPSQAPRLEPLREEDLAKGPDLHILMAQRQVQVAEEGLQDFHRALRCYVDFTGAQSHCLHVSAQKMLDGASFTLYEFWQDEASWRRHQQSPGSKAFQRILIDHLRAPDTLTTVFFPASWWIMNNN
The following text describes a protein:
Function:
Required for vacuolar assembly and vacuolar traffic.
Subcellular Localization:
Vacuole.
Sequence:
MEEERESGEVENMDRPQEAVVDLENSRPDQALDQLPSVSALIEETGQEEAIAIPQETKQIPPGNDREPSSDNVSVRSSGSSIPEDQDEEDDQEEEEEEEEEEEEEEEPLFKYQRLEGHIDKLFQNDNASALTTSEKHIGLGTHNGVVYILNHRIELIKRFRPHSATIYDIKIEVSEQFVATASMDGKISIVQLSGGNDVFILDLKRPMMAVAMEPLYHKHPNKRQFISGGLAGNLTLHEKGWLGNKETVLHSNEGSIWSAEWKNNLVVWANDTGIRIIDINTHQKVAYIPRGADEPRADLYRCHFSWSTPEKLLVGWADTIRVVSIKENSAPTSIHRGLIPTSSTSSPNLPVKVEMVFQVDCIISGICAWEAGGSPDIAILAHTSEPEDSDVDVTGNERPPSDDGTADSIAPRSSKRRPAQRPELRIISSNGEEISSDALNINSFQRYQPNDYCLCYLLPPSESGKKKKMDDESLYVMSPKDLILVELRNRSDHISWMIDHENYEGAMKEVEEAGLAGAHGYSLSEIGQKYLNHLISQGQFQVAANASPSILANDVKAWEDWIFMLTEKGQLDVIIPHVPTEAPRLSKVVYEIILVHLLRSNTQEMLNMIRKWSPELYSIPAVLSAALDRLSRDSGSSGILMTCIAELYILNHQPGKAVSYLLRLRKPEVFDLIKENNLFTDVQDQALLMIKFSDELNRKNLNRSDDERSGDEAKGLSKSPATQDEQSPREYGAAINLLVQHTYSIPVARVIAQLADHRRYQFMYLDALFEVDPSLGTDYGDLHVDLFAEFDRQRLMKFLRASTFYDLEKAYQICQDLNFVPEMVYLLGRMGNNKKALFLIIDRIGDVHRAIEFAKEQNDDDLWEDLLRYSETRPAFIRGLLDNVGSEIDPIRLIRRIQNGLEIPDLKASIIKILQDFHLQISLIEGCRSIMVSDCRDLSKVYYASQTLGALGDPSLRCQKCNRLLTEPSKPVAATDDGTELVADNSIAMMGSALSIMFLCRHSFHSLCVFDSNTVLAALAEQQLDRSRSALGDAIVDRAGERYNAINLKFAQTLILRSGDGSCPICTSGSKKSFLSHPN
The following text describes a protein:
Function:
Mediates uptake of riboflavin and roseoflavin, a toxic riboflavin analog; may also transport FMN. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKVKKLVVVSMLSSIAFVLMLLNFPFPGLPDYLKIDFSDVPAIIAILIYGPLAGIAVEAIKNVLQYIIQGSMAGVPVGQVANFIAGTLFILPTAFLFKKLNSAKGLAVSLLLGTAAMTILMSILNYVLILPAYTWFLHSPALSDSALKTAVVAGILPFNMIKGIVITVVFSLIFIKLKPWIEQQRSAHIH
The following text describes a protein:
Function:
t-SNARE that functions in transport from the endosome to the late Golgi and on the endocytic pathway.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Endosome membrane; Single-pass type IV membrane protein.
Sequence:
MFRDRTNLFLSYRRTFPHNITFSSGKAPLGDDQDIEMGTYPMMNMSHDISARLTDERKNKHENHSDALPPIFIDIAQDVDDYLLEVRRLSEQLAKVYRKNSLPGFEDKSHDEALIEDLSFKVIQMLQKCYAVMKRLKTIYNSQFVDGKQLSREELIILDNLQKIYAEKIQTESNKFRVLQNNYLKFLNKDDLKPIRNKASAENTLLLDDEEEEAAREKREGLDIEDYSKRTLQRQQQLHDTSAEAYLRERDEEITQLARGVLEVSTIFREMQDLVVDQGTIVDRIDYNLENTVVELKSADKELNKATHYQKRTQKCKVILLLTLCVIALFFFVMLKPHGGGSGGRNNGSNKYNNDDNKTVNNSHDDGSNTHINDEESNLPSIVEVTESENDALDDLL