lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Probable serine protease inhibitor.
Domain:
The reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the carboxyl group of the serpin reactive site and the serine hydroxyl of the protease. The resulting inactive serpin-protease complex is highly stable (By similarity).
Sequence:
MDSKRKNQELSTSETADPSLSKTNKKQKIDMQEAMKNQNEVSLLLVGKVISAVAKNSNCVFSPASINAVLTVTAANTDNKTLRSFILSFLKSSSTEETNAIFHELASVVFKDGSETGGPKIAAVNGVWMEQSLSCNPDWEDLFLNFFKASFAKVDFRHKAEEVRLDVNTWASRHTNDLIKEILPRGSVTSLTNWIYGNALYFKGAWEKAFDKSMTRDKPFHLLNGKSVSVPFMRSYEKQFIEAYDGFKVLRLPYRQGRDDTNREFSMYLYLPDKKGELDNLLERITSNPGFLDSHIPEYRVDVGDFRIPKFKIEFGFEASSVFNDFELNVSLHQKALIEIDEEGTEAAAATTVVVVTGSCLWEPKKKIDFVADHPFLFLIREDKTGTLLFAGQIFDPSELSSALDRA
The following text describes a protein:
Function:
Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Localizes predominantly in the nucleus.
Sequence:
MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFPATATAAYPDFSASCLAATPHSLPQEEHIFTEQHPVFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGEDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPVSPNGQDPEDGDSTASPSSE
The following text describes a protein:
Function:
Accessory component of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Sequence:
MRPVVSTGKAWCCTVLSAFGVVILSVIAHLFNTNHESFVGSINDPEDGPAVAHTVYLAALVYLVFFVFCGFQVYLARRKPSIELR
The following text describes a protein:
Function:
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues (By similarity).
Sequence:
MSNKNQRKTKSKDREVRKTNDSSILSKASVEKCGYPGFTVGHSYYQPFIQKSPRRSPSVNRGYWTRCMAIRFAVYQFLKNKTGKRKAIVNLGAGYDPLAFQLLSSHEYNTDDVVFYDVDYPETIENRVQMIRSDSFLSSIVLEDKEFDLDGTEIHTKNYHSFGCNLNLLNQLESCLEKYGIDYCNDAILFISEVAAVYMPRQASEKLIRWMSKFPDAHSCFFEQIAPATFDHPFANVMVKHFKEWGTPLHGLYAYPTIESLKSRWVKNGWEYVEILDVCTFWNFLMDSKLKHLCEMVEPFDEWEEFYFFLQHYSIQHASSKLVGKYDLVESPDPCMQYIRYVKSEIIFNNSPLTLRNSIYSLKRTDLPACLKELPSLRLPAVCDLDDSVIVQGGLSTAGRSKDAYLISEKDDGSIMKITTDSLTSCMGQSVVSIDKKTCMFIGGRESPKKILSSCIYFADGNWSDFPSLPYASHRASSVSIKHNGSSYVVLLAGKPFGGCLIWSDSKRKWNTLKCKDPLFYSRWGACLHWSSKLKKGILCGGMNELNEPVREVLEWEMVLRDDDHFEIVTRVLNFDVQVEILLSRIGSKVVFFGDDSKPIIVGGAAVFRTILWEEESVCINMNDYSVTGVCIEETEKRPVFTMFGISGMGNHLQIFGGGCICFSFGSCLNENATFYKLVSA
The following text describes a protein:
Function:
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MSSGVPVLHWNFGIGPITCHAWNKDRTQIAVSASSNDIHIFEWRNGDWQSIHTLSEHDLPVTGLDWGTKTNRIVSCSQDKNAFVWTFDKNVWKPELVLVRFNRAATYVKWSPLENKFAVGSGAKLVSVCYYEKENDWWVSKQIKKPIRSTVTCLDWHSNNVLLAVGSCDFKCRVFSAYVKEVDEKPSPNPWGQKMPFGQLMSEYSVGGWVHRVAFSPSGCRLAFVSHDSSVSFVDSTVDSQKVQNLLTIHLPFTTVEWITENSVVTAGHDCSPVLFVVSQDVLKEVCKLDVPSAAKSSTVNSALQLFKNIDRNNAAEKINVALKTLHQNRITQILPHSGTVGNVVKFTTCGTDGIVALWDLKETIEFCRNHPSLV
The following text describes a protein:
Function:
Probable glycosyltransferase involved in pectin and/or xylans biosynthesis in cell walls (By similarity). Together with IRX14, required for xylan and pectin synthesis in seed coat epidermal (SCE) cells. Collaboratively with GAUT11, essential for the accumulation of seed mucilage, a gelatinous wall rich in unbranched rhamnogalacturonan I (RG I), and for shaping the surface morphology of seeds.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MTGLGVRSSSYGSLEKTGLNGVVLPIQITTTTRTKPSKMQKDREGIVHWICKFAGRKKVGMLLLFLISAVVFLRVLYVGKGEDSQEGQGPPSLHFNGSSGVNYSNMLQTNEELNMNIGNISFKAKEVIVFPPPPIHFLGYSLPQGHPCNSFTLPPPPADRKRTGPRPCPVCYLPVEEAVALMPNAPSFSPVLKNLTYIYEEPLNRETEFGGSDFGGYPTLKHRNDSFDIKETMSVHCGFVKGPQPGRNTGFDIDEADLLEMKQCRGIVVASAVFDAFDDVKAPQNISKYAEETVCFYMFVDEETESILKRERGLDGNKKVGIWRVVVVHNLPYSDGRRNGKVPKLLVHRMFPNARYSLWIDGKLELVVDPYQILERFLWRKNATFAISRHYKRFDVLVEAEANKAAGKYDNASIDFQVDFYKNEGLTPYSVAKLPITSDVPEGCVILREHVPISNLFTCLWFNEVDRFTSRDQISFSTVRDKIAAKTNWTVSMFLDCERRNFVVQRYHRAEQERFARQRPPVPNFPPPPPSPPPPVLISSDLPRKMSSGRATPPRRRGRDRRSGQRGHRKANLPVRLPDSA
The following text describes a protein:
Function:
Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface.
Subcellular Localization:
Cytoplasm. Nucleus. Secreted.
Sequence:
MRAAILLGFLGVALAAPLLPQPLLSASNSRELLMGLGNARLRGLPPGLQASANPLIFPLPGALHHGPRPLGLSWPSLGHFGGLVPNEVPLPGQARLAQRSQAVQQEAPRLQMLQQNQQDPYQIIPCFFSFGVPQVWGQMVPYYPVCVYGAQDPPLQLSALAGPPQPPEQVPSYPELGCLTQQAQPPIENVLPYTQREMVNLGYPYAGIFMPSYPLKHQTANILASPTDNVVPLELLEEEVKELKVFLMSEIKFLLLLLKRKGSGTYGWWS
The following text describes a protein:
Function:
Part of the yraHIJK fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim operon. Probably involved in the export and assembly of fimbrial subunits across the outer membrane.
Miscellaneous:
MISCELLANEOUS: The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein.
Sequence:
MPQRHHQGHKRTPKQLALIIKRCLPMVLTGSGMLCTTANAEEYYFDPIMLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQKKITFTANAEQLLQPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDFNHQQLNLSIPQIALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNMQNGANFGPWRLRNYSTWTRNDQTSSWNTISSYLQRDIKALKSQLLLGESATSGSIFSSYTFTGVQLASDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVSAGAFEINDLYPSSNSGDLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDSKEPEFAEATAIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDNQHSFHGYQWRTQYIKDIPETNTNIAVSYYRYTNDGYFSFNEANTRNWDYNSRQKSEIQFNISQTIFDGVSLYASGSQQDYWGNNDKNRNISVGVSGQQWGVGYSLNYQYSRYTDQNNDRALSLNLSIPLERWLPRSRVSYQMTSQKDRPTQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHNSSLNASYRSPYGTFSAGYSYGNDSSQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDANGASGVRIQNYPGIATDPFGYAVVPYLTTYQENRLSVDTTQLPDNVDLEQTTQFVVPNRGAMVAARFNANIGYRVLVTVSDRNGKPLPFGALASNDDTGQQSIVDEGGILYLSGISSKSQSWTVRWGNQADQQCQFAFSTPDSEPTTSVLQGTAQCH
The following text describes a protein:
Function:
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (Probable). Expression of the complex plus RibU in E.coli allows riboflavin uptake; uptake does not occur in the absence of RibU or the EcfA1A2T complex.
Miscellaneous:
MISCELLANEOUS: Structure 4HLU is probably in the open state.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MRIEVVNVSHIFHRGTPLEKKALENVSLVINEGECLLVAGNTGSGKSTLLQIVAGLIEPTSGDVLYDGERKKGYEIRRNIGIAFQYPEDQFFAERVFDEVAFAVKNFYPDRDPVPLVKKAMEFVGLDFDSFKDRVPFFLSGGEKRRVAIASVIVHEPDILILDEPLVGLDREGKTDLLRIVEKWKTLGKTVILISHDIETVINHVDRVVVLEKGKKVFDGTRMEFLEKYDPRFFTSKMLVMRRLVLKGEDPFSMSDDELLERVCNS
The following text describes a protein:
Function:
Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
Subcellular Localization:
Cytoplasm.
Domain:
The C-terminal coiled-coil domain is crucial for aminoacylation activity; ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.
Sequence:
MFKKELSISEIYKPQEIEKKLYSFWEEKGFFKPDSDSEKPSYCIVIPPPNVTGTLHMGHALNATLQDILIRWKRMLGYAALWIPGTDHAGIATQNVVERQLLQEGIDRYQLGRTAFLERVWQWKESCGGRIIEQLKRIGASCDWSRLRFTMDEGLSQAVKEVFLRLFEEGLIYRDLRLINWCPRCHTALSDLEVEHEELEGKLYYIKYPLKEDPEKFITVATTRPETMLGDTAVAVNPEDKRYKNLIGKVLILPLINREIPVIADSAVDMEFGTGAVKVTPSHDFNDAEMAQRHNLPYVCVINEEGRMTEEAGKYKGLERYDARNKIINDLTELGLLEKTEKHKHAVGHCYRCKTVIEPFQTVQWYVKIKPLAEEAVRVVEEGKIKFIPEGWVNNYYAWMRDIKDWCISRQLWWGHRIPVWYCAECKTIDGKEQGDLIEILFYKPITLNGKEIWGGSFNELKKLGVSKEEIEQRAKMIKIPKEIKHFANREEPKTCPYCGSKELIQDPDVLDTWFSSALWPFSTLGWPEETEDLKRFYPTNVLVTGFDIIFFWVARMIMMGMKFMKDVPFRDVYIHALVRDSKGQKMSKSKGNVIDPIVMIEKYGADAFRFTLAAFAAQGRDIKFSEERVEGYRHFINKIWNAMKFIMSFAHLRTKEEVKLEDVKSLKDRWILSKLSDAIYETNRALDAYRFNDAAGTVYQFLWHEFCDWYIELSKVVLYSDTEEKDETVNCLFYVFENILKLLHPFMPYVTEEIWLNILGKEKSLMISLYPTHDLINKDEEAIDKMEHIIEAISGIRSIRGELNIAPSLNVDVYIKSLTPQAENILNEGYQFILKLAKAKSLKIQKDLSRAKGSAVSVKKNFEIYIPIKGLIDIEQEKKRLLKELQKTEQDINFLNKKLMNEDFIKNAPEDVVKKDKEKYEGLLVKHDKIKENLSVIEELKN
The following text describes a protein:
Function:
An ATPase (shown for residues 80-506). Part of the ESX-5 specialized secretion system, which is responsible for the secretion of EsxN and a number of PE_PGRS and PPE proteins, including PPE41.
Miscellaneous:
MISCELLANEOUS: Part of the eccB5-eccC5 operon, which is essential for in vitro growth.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MAEESRGQRGSGYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEIEPGRRQTLAVVASVSAALVICLGALLWSFISPSGQLNESPIIADRDSGALYVRVGDRLYPALNLASARLITGRPDNPHLVRSSQIATMPRGPLVGIPGAPSSFSPKSPPASSWLVCDTVATSSSIGSLQGVTVTVIDGTPDLTGHRQILSGSDAVVLRYGGDAWVIREGRRSRIEPTNRAVLLPLGLTPEQVSQARPMSRALFDALPVGPELLVPEVPNAGGPATFPGAPGPIGTVIVTPQISGPQQYSLVLGDGVQTLPPLVAQILQNAGSAGNTKPLTVEPSTLAKMPVVNRLDLSAYPDNPLEVVDIREHPSTCWWWERTAGENRARVRVVSGPTIPVAATEMNKVVSLVKADTSGRQADQVYFGPDHANFVAVTGNNPGAQTSESLWWVTDAGARFGVEDSKEARDALGLTLTPSLAPWVALRLLPQGPTLSRADALVEHDTLPMDMTPAELVVPK
The following text describes a protein:
Function:
Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MSKPQTKIQYPFWYGGAASMAACLVTHPLDLAKVRLQTATKPGQSLLSMIYQIITKEGVFKIYSGLTASLLRQATYSTTRFGIYEFLKEQYMESIATTGGTEQKKPSTAVLLPMSMIAGALGGLVGNPSDVVNIRMQNDSTLPINQRRNYRNAFDGIYKICQQEGINSLFRGLTPNLIRGVLMTASQVVTYDIAKSILVDHIHMDPSKKSTHFSASLIAGLVATTVCSPADVVKTRIMNSKGSTGGGSGGDGVNGNAISILKNAVKHEGIGFMFRGWLPSFIRLGPHTIVTFLVLEQLRKFKLGMSRSD
The following text describes a protein:
Function:
Photoreceptor that binds cis-retinaldehydes. Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light. May be involved in the optokinetic visual tracking response. May be involved in the regulation of retinal hyaloid vessel growth and regression.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MNCGRRRRLRGRLLPEQAAPSSCDVSFLDRTCDVTASSPEGNFLGWCISAARLSESQAVVLPPSSQNIFPTADVPDHAHYTIGATILAVGFTGVLGNLLVIYTFCRSHSLRTPANMFIINLAISDFFMSFTQAPVFFASSMYKRWIFGEKACEFYAFCGALFGITSMITLMAIALDRYFVITRPLASIGVISKKKTGFILLGVWLYSLAWSLPPFFGWSAYVPEGLLTSCSWDYTTFTPSVRAYTMLLFCFVFFIPLIVIIYCYIFIFRAIQDTNKAVHSIGSGESTASPRHCQRMKNEWKMAKIALVVILLYVLSWAPYSTVALVAFAGYSHILTPYMNSVPAIIAKASAIHNPIIYAISHPKYRMAIAQNFPCLRALLCVRHPRTRSFSSYRFTRRSTMTSQASDISWLPRGRRQLSLGSESEIGWNNMEAGTTSLTSRNQQGSCRMDQETMETRELAAIAKAKGRSWETLEKTLEEMDDSSLLEVSVDMEQ
The following text describes a protein:
Function:
Probable component of an adaptor protein complex. Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
Sequence:
MNSSALNLIQFLESSKIQVPGGLKSVKGILDFDFYDLVKNIGESTSREEEVHIIQNEIIKLKSCFSKEQSKDKKRECLIRMIYCHMLGYDVPFGHIQALNMTQDSEILNKRTGYLTLSLCLPERHELLIMAVNSILKGLNSSNYLEVCSALTAMCKLIDNDTIPAFLQKVLQLLNHQKPIVRKKSVTVLHRFYRLVGDSFLDDDQIIDKLRQSLCDRDPSVMSASICIFLDISEKHSTLKDNNNQINNNNNNNNSNQIKKKNNEEINRSKNLISMLKELVPSFVGILKQVAEGRLPNSYIYHGIHHPWLQINLLKLLSNLGYQDKDSSNHMYTVLLFTMQQSQKFKNNVGFAILYETIKTLTLIHPNLQLIEQCSKNIAIFLKGKHHNLRYFGIKALASIVKVSPKLVLPYQVEVIESLESPDETLKRKSFDLLYKMTNQTNVVPVCSKLIEQLVLSKDQNFKSELISQITNIAEKYSPNDIWYIDTISTVLSILPNENNKDNNNNNNNNNNNNNNYQFAYNLIRLVSEEDDIKVKQHISEIYLNNIMISNEQQQQQQQENQNNLQQFSDIYIKIMSWVISEYSNLIVSNNGVIESDIISYLCDLLEKDYQGETKSWIIIGIGKLVAQLGKSLPMLELMTKKFKSSKSLICQQRSSELNEILKNPKSMSLILPLDAYCEDIDFNKIFNKFNDYSNKVGGKQYIPYEKRKNTPLVDISDGSSSHSNEKGLNFQYPPPPDPFNPHHNQQQLYPVHQHQPPSNHQQQQQQQQQQQQQQLQLFPQQPQQPQQLLLLGEDDTINLNNNSLVPVNNDQQLQPHQHQQQQQNQQQQQQNQQQQQQQNPQYPNNQLVTVPDQNAPKPIGLPKPSKVLWTKKGFVGNKQTPPQNATPQQQQQQQQQQTQNTLSQQQIQKHQQTHNNIDPEKEKLAKQLFGGFSENNNRNENSNNTDNNQNNVGITSKLQNKKSNNENNINNNKKESYLEELIDLSPNLISNINITNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNLLLVDVEGDEQKEVKNSSCSSGNSELINLNLDENTTKNINGNLLGDDLEELNKN
The following text describes a protein:
Function:
Acts as an adapter protein downstream of several growth factor receptors to promote cell proliferation, migration, and redistribution of actin fibers (By similarity). Specifically involved in INS/insulin signaling pathway by mediating MAPK1/ERK2-MAPK3/ERK1 activation and DNA synthesis (By similarity). Promotes insulin-mediated membrane ruffling (By similarity). In response to vasoconstrictor peptide EDN1, involved in the activation of RAP1 downstream of PTK2B via interaction with phosphorylated BCAR1. Inhibits cell migration and invasion via regulation of TGFB-mediated matrix digestion, actin filament rearrangement, and inhibition of invadopodia activity. May inhibit TGFB-SMAD signaling, via facilitating BCAR1 and SMAD2 and/or SMAD3 interaction (By similarity). Regulates EGF-induced DNA synthesis (By similarity). Required for the maintenance of ocular lens morphology and structural integrity, potentially via regulation of focal adhesion complex signaling. Acts upstream of PTPRA to regulate the localization of BCAR1 and PTPRA to focal adhesions, via regulation of SRC-mediated phosphorylation of PTPRA. Positively regulates integrin-induced tyrosine phosphorylation of BCAR1. Acts as a guanine nucleotide exchange factor (GEF) for small GTPases RALA, RAP1A and RRAS (By similarity). However, in a contrasting study, lacks GEF activity towards RAP1 (By similarity).
Subcellular Localization:
Cytoplasm. Cell junction, focal adhesion. Note=Localization to focal adhesions depends on interaction with PTPRA.
Domain:
The SH2 domain mediates interaction with tyrosine-phosphorylated proteins (By similarity). However, not involved in the binding to phosphorylated BCAR1 (By similarity). Required for cell cycle progression in response to INS/insulin (By similarity). Required for regulation of EGF-induced DNA synthesis (By similarity); The Ras-GEF domain appears to adopt a closed conformation rendering it incapable of carrying out canonical exchange factor function, this closed conformation is probably required for interaction with BCAR1.
Sequence:
MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLTEHRPDAYQDVSIHGTLPRKKKGPPPIRSCDDFSHMGTLPHSKSPQQNSPVTQDSIQESPWQDRHCETFTFRDPHLLDPTLEYVKFSKERHIMDRTPEKLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLRCLEERYGISPGQAREGSLTEGRPDVTKRLSLTMGGVQAREQNLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPCPNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKAPSSPSAWLNSEANYCELNPAFATGCGRGAKLPLCAQGSPTELLTAKQNGALGPRNSGINYLILDDDDRERPWEPAAAQTEKGQWDKGEFVAPLLETVSSFRPNDFKSKFLPPENKPLETAMLKRAKELFTNNDPKVIAQHILSMDCRVARILEVSEEMRRNMGVSSGLELITLPHGHQLRLDIIERHSTMAIGIAVYILGCTGTLEDRAATLSKVIQVAVELKDSMGDLYSFSALMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKILHEGRESTCVPPNNVSVPLLMPLVTLMERQAVTFEGTDMWEKNDQSCEIMLNHLATARLMAEATDSYRMNAERILAGFQPDEEMNEICKTEFQMRLLWGSKGAQVNQAERYEKFNQILTALSRKLEPPPVKQAEL
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
Subcellular Localization:
Secreted.
Sequence:
MCLALTPITIKDVIPIPTLHLNHYPQIFVAMEAQYSNNKTPILFVIILATSAIGQGTRVGFYRTTCPRAEIIVQSVVQSFVNSNTTIAPGLLRMFFHDCFVRGCDASILLDGSYGEKTAPPNNRLRGFEVIDAAKSQLETICPGVVSCADILALAARDSVVQSGGFWWEVRTGRRDGLVSRKSDATNLPGRKDSIEVQIKKFAEKGLNIQDLVTLTGKLSTKHTTTVYGHNITNGTDLVIKKSMDVFMGFHDHPGGHTIGTAACELFCYRLYNFNSTNGPDPAINQTFLPHLRSLCPEGGDDANRVDLDTGSVHKFDISYYENLKNGRGILESDSQLWNDPRTQRFVEWFLGGSREQQSKFSVEFGKSMVRLGDVGVKTGDEGEIRRVCYAIN
The following text describes a protein:
Function:
Transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MTQPEDEVMVFLSSILNLDLDKEEDGGLNEKKMKRKRKKRKMKNVDDDDDDKLFKFKRKLSEQQTMFLESKFKEDMKLDFGRKLHLASEMGLDPKQVAVWFQNKRARWKNKQMEDRYAKLKSQHQEILFQKCHLESQVLALRQQLIETQAQVQAVYSDQVSNGSGSDGRGSTTSPNTSFSIDTPQNCQFFPIEEDQFVYNTHDEHNFLDGGGMFDWYIF
The following text describes a protein:
Function:
Metal transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
TFHSFFCPCLQLPTVWPRPLPHLPLLIGSRYSFRFSLGGRRRRLTPDWLSCQRHRRGCSASSNMAVAVVGLLLLAGFGDTLVGSAHVDDNVEARVLGLRLEEGAGVSMSGGVIRARPGSSFRLRLYGSGLRNDTWPWVSIGSPGNNTCSPGSDSPLQLLQEFRVCGEHSGLVTVRAENESEGRGLMYPLCTRKGNSWAPFPGGDTLITVLGVGEEEEKPPWRGDEHQCSLGSFNSRLFTFRDEAPSVEPPETDARPYLSSWLLALLIVLCVLLSGLLRGLQLSTLALEPPELGLLRDWGTPSERHGATRLDPLRTRWGGYTLISMLALCCLTNSAVAVLLYHAIGSLPAAIFSAAGLLLLAGEALPAAVSSRWGPVLAPKCLWLTHFFLLLAGLLSFPLSWLLEAVFGQDPSCCRLRVRILEMARCGDPYSELVRDEFSKGALRNRTVEDIVTPVGKCFMLPSDAFLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPQDCTPLSTITRFYSHPVHFVFSDTKLDAVLEEFKKGKSHMAIVQKVNNEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESEDCMHKVKKKRQPAQPILIPRGGDDLSFFRSSEAEQKVKISPQLLLATQRFLTQEVDLFGTSRVSEKALLNLLKFPGVTQEVKFDDSDRLSPEHFLYLRSQPVDYFILILQGRVQVEIGKEGLKFENGAFTYYGVAALSPCLLGHQSPGIQNSPSDSSFYYPDYTVRALSDLQIVKVSRLQYLNAVRNSNSHTTTQSPDSMELKILPNSQTQLLNTRNMESESSKEKPTDIWPQNAGEEVMKEECLSDPPYHASEPGTLSLPPPQGPVTIAESIIMS
The following text describes a protein:
Function:
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTSSMLFNITTFTYLVSMLAFFAFLASRNRHLGMAGSLISYFGFFVHTAAILLRWKESYDIGHGHAPLSNLYESVVFFAWTIVLIFGIIDLKYKYRVVGAFVMPFALLGMAWAQLTLNSGIEPLVPALQSNWLLYHVVTCFLGYAAFAVACGISIMYLIKAGKEDSSQSAQAGGIISMFPPTKILDDLNYKAIMIGFPLLTLGIITGAAWANYAWGTYWSWDPKETWSLIVWFVYAAFLHARFTRGWVGKRAAILSIVGFAATIFCYLGVNLLLSGLHSYGGG
The following text describes a protein:
Function:
Not known; probably binds four calcium ions.
Sequence:
MSATVHYKDIRKGMEKDLESLFKKYDSDRNGKITYIEIVETLRKAGKKNPERIADLLFRDDTDKNGELTIEEAKLRIVRMNDEKIEKVLNWDVEKFINDNDKDGDRKITRDEVLQRFTEQGAEDPELITDSIFRQMDLDRDGVITCDEIKEFNRKKKFSFLKSSAPKQ
The following text describes a protein:
Function:
Promotes apoptosis when overexpressed.
Subcellular Localization:
Nucleus.
Sequence:
MALPPFFAQSRQGPPPPQPPPSAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRAPAEASRGGGGGGAFFPVPPPPLPPPPPQCRPFPGPDAVERPRPPPPGPGPPWSPRWAEAPPPPDVLGDAALQRLRDRQWLEAVFGNPRRPGGLRTPRTPAGPSLGEVRARLRSALRLVRRLRSLGQSLREAEADGAAWASLHAQAAPLRAELAERLQPLRQAAYVGEARRRLERVRRRVRVRERARDRRLSGRRGAQRTEREQEIDRWRVKCVQEVEEKKRDEELKAAADGVLAEVRKKQSDTKRMVDILRALEKLRKLRKEAAARKGVCPPASADETFEHHLQRLRKLIKKRSELYEAEERALRVMLEGEQEEERRRELEKKQRKEKEKLLLQKREIESKLFGDPDEFPLAHLLQPFRQYYLQAEHSLPALIQIRHDWDQYLVPSDHPKGNSVPQGWVLPPLPSNDIWATAIQLH
The following text describes a protein:
Function:
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
Subcellular Localization:
Cytoplasm.
Sequence:
MKNDKLFLTGKILEIIHGDKYRVMLENNVEVDAHLAGKMKMKRTKILPGDVVEVEFSPYDLKLGRITQRK
The following text describes a protein:
Function:
Degradation of glucosinolates (glucose residue linked by a thioglucoside bound to an amino acid derivative) to glucose, sulfate and any of the products: thiocyanates, isothiocyanates, nitriles, epithionitriles or oxazolidine-2-thiones.
Subcellular Localization:
Vacuole.
Sequence:
MRSKCLLLLLLINLACIGVLAKNHSSRPRLRRNDFPEDFIFGSATSAYQCEGAAHEDGRGPSIWDTFSEKFPEKIKDGSNGSIADDSYNLYNEDVDLLHQIGFDAYRFSISWSRILPRGDLKGGINQAGIDYYNNLINLLLSKGVKPFVTLFHWDLPEALEHAYGGFLGSEIVNDFRDYAELCFQKFGDRVKHWTTLNEPFTVVHEGYTIGEKAPGRCSSFTNPKCFGGDGATEPYIVGHNFLLAHGAAVKIYREKYQAIQKGKIAAARATAFTFDYFLEPIVYGRYPADMVNYVKGGRLPTFTPEESSILKGSYDFVGVNYYSSFYVKDVPCATENITMNTDSCVSIVGERNGVPIGPAAGSDWLLIYPEGIRDLLLHAKLKFNDPALYVTENGVDEASIGEIFLNDDLRIDYYAHHLKMVSDAILMGVNVKGYFAWSLMDNFEWSEGYTVRFGLVFVDFEDGRKRYLKKSAKWFMRLLKGEYNGMRQKVAVI
The following text describes a protein:
Function:
Acts as a transcriptional repressor of the pdxK gene, encoding a pyridoxal kinase involved in the vitamin B6 salvage pathway. Also represses transcription of its own gene. Binds to the ptsJ-pdxK intergenic region, but does not bind pdxY and pdxH promoters. Among all six B6 vitamers, only pyridoxal 5'-phosphate (PLP) clearly binds to the protein and acts as an effector molecule for PtsJ, inducing a protein conformational change that increases affinity for DNA. Thus, PLP stabilizes protein-DNA interactions, reinforcing repression.
Sequence:
MIDGKTANEIFDSIRQHIIAGTLRAEDSLPPVRELASELKVNRNTVAAAYKRLITAGLAQSLGRNGTVIKGSPSPVALEGGDPHTPLHDLSGGNPDPQRLPDLSRYFARLSRTPHLYGDAPVSPELHAWAARWLRDATPVAGEIDITSGAIDAIERLLCAHLLPGDSVAVEDPCFLSSINMLRYAGFSASPVSVDSEGMQPEKLERALNQGARAVILTPRAHNPTGCSLSARRAAALQNMLARYPQVVVIIDDHFALLSSSPWQPVIAQTTQHWAVIRSVSKTLGPDLRLAIVASDSATSAKLRLRLNAGSQWVSHLLQDLVYACLTDPEYQHRLTQTRLFYAARQQKLARALQQYGIAISPGDGVNAWLPLDTHSQATAFTLAKSGWLVREGEAFGVSAPSHGLRITLSTLNDSEINTLAADIHQALNR