lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in thiamine metabolism. Does not possess 5-formyltetrahydrofolate cyclo-ligase activity in vitro.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MIRLSPGFAINPRFRSDSFVNSQKPPFLSVQIGSQRRNLSRIGSENGDGVAFDAVAYEADRLSLDAAAMEDMAETAKKELESDPDSDPKAWKWVIRKKMWDLMEARNYAMSPRPVHHRIPNFVGASAAARKLAELDAFRMAMVVKVNPDSPQKQIRFLTLSGEKKLLTPQPRLRTGFFSVLESDLLKPETIMEACTSVGVAKYGRAIGLDEKIKVDLIVIGSVAVNPQTGARLGKGEGFAELEYGMLRYMGAIDDSTPVVTTVHDCQLVDDIPLEKLAIHDVPVDIICTPTRVIFTNTPIPKPQGIYWDKLSPEKLRQIRILRELKNRLEKKTGRKLPTGPSEKLPPTAERKRR
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence:
MLSIGAMANIKHTLQKELFLASGERLLSVVTVVKKKDKKPCYLCVVTTAPPVPVVTLCLIKQSEQREGEYKRKRSWQLDEIKWVDGRNEQFETHEFDLQLEKLYKWYALNPHERQNFLAVLNRQIQKSVRGQRAEFRNVPAAWLSEKSPEKVALGRAVQKTQHMDDEEDEEEEAQEFTALTDKEANELGKLFSECDFAIKDAEQFIEQLSRELHDLDGANMQSVLASEQKVLKMMEHIDNAISEADKFENRLDSYEDILGHVKETMEKIGGKNAMIEIANNNNIKLMKELNKVISQLDLPHSQQQALDEPDLKTANGRKAAIAAAQCLQQAMNSDIDPALLRLEAVQDQRKRFEKWKQKFSATVSRFMNNLFIHLGNEIGDMQVTSTELTLPNHSNVHRELTPYTELMHWTKAMDRKTYDGLMRVYTASLSKIYDRDVRNFFNLAKIQVTEKLRNSREDLDMSTSSRKSAVSTIPYGTLGINRDQWGPGVETADRMRFDALLEKVLAELEPIALQEQLFCINFFQMDVISPTTKNTQTTLEMEKAVDMTQSIISGAVSPSGDGVPQKRIDRQINEDVRKLMMGLFGCLEPELVSFIQSFERVDSFYSLYVFVRLTQHVMSAQDTHSFLSMTFASALVQVKRSFDRFMQNQLLSIREAKLHKRSKAILPYVENFENFAQTAEGIFRKSDRRTDMEKWYLQLVNAIFEGIQLHSQEHPKTPVQVVRMENYHHMYALLAQLKVPGLDALKKEAKKCYNDALKAYVTQYFGRPLEKLNQFFEGVQLKVAQGVKETEISYQMAFSKQELRKVIAQYPAREVKKGLENLYKKVEKHLSEEENLLQVVWHAMQEEFIAQYNYLEERIQKCYAGAMINLEFNIQDILAFFSDIARSH
The following text describes a protein:
Function:
May be involved in the regulation of the cytoskeleton through interaction with the subpellicular microtubules. May be involved in parasite mobility and attachment to the surface of the host cell. Behaves as a strong immunogen during infection.
Miscellaneous:
MISCELLANEOUS: There are four copies of the KMP-11 gene in T.cruzi.
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Sequence:
MATTLEEFSAKLDRLDAEFAKKMEEQNKKFFADKPDESTLSPEMKEHYEKFEKMIQEHTDKFNKKMHEHSEHFKAKFAELLEQQKNAQFPGK
The following text describes a protein:
Function:
Inhibitor of viral mouvements which confers resistance to some tobamoviruses including tomato mosaic virus (ToMV) (e.g. isolates L, W3 and SL-1) and tobacco mosaic virus (TMV), but not to resistance-breaking isolates (e.g. B7, LT1, LII, Ltbl, ToMV2, and ToMV1-2) ToMV and tomato brown rugose fruit virus (ToBRFV). Elicits a hypersensitive reaction in response to avirulent (Avr) movement proteins from resistance inducing tobamoviruses (e.g. ToMV and TMV) strains, thus leading to programmed cell death.
Miscellaneous:
MISCELLANEOUS: Transgenic tobacco (cv. SR1) plants expressing Tm-2 exhibit resistance to tobacco mosaic virus (TMV) and tomato mosaic virus (ToMV), tobamoviruses that can multiply in tobacco (cv. SR1); MISCELLANEOUS: The Tm-2, Tm-2(2) and Tm-2nv alleles present in the tomato mosaic virus (ToMV/TMV)-resistant tomato cv. Craigella isolates GCR236 (AC Q71BH0), cv. Craigella GCR267 (AC Q71BG9) and cv. Yukang 2 (AC Q5MLE9), respectively confers resistance to ToMV but not the tm-2 allele present in the ToMV-susceptible tomato cv. Craigella isolate GCR26 (AC Q71BH1).
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MAEILLTSVINKSVEIAGNLLIQEGKRLYWLKEDIDWLQREMRHIRSYVDNAKAKEAGGDSRVKNLLKDIQELAGDVEDLLDDFLPKIQQSNKFNYCLKRSSFADEFAMEIEKIKRRVVDIDRIRKTYNIIDTDNNNDDCVLLDRRRLFLHADETEIIGLDDDFNMLQAKLLNQDLHYGVVSIVGMPGLGKTTLAKKLYRLIRDQFECSGLVYVSQQPRASEILLDIAKQIGLTEQKMKENLEDNLRSLLKIKRYVFLLDDIWDVEIWDDLKLVLPECDSKVGSRIIITSRNSNVGRYIGGESSLHALQPLESEKSFELFTKKIFNFDDNNSWANASPDLVNIGRNIVGRCGGIPLAIVVTAGMLRARERTEHAWNRVLESMGHKVQDGCAKVLALSYNDLPIASRPCFLYFGLYPEDHEIRAFDLINMWIAEKFIVVNSGNRREAEDLAEDVLNDLVSRNLIQLAKRTYNGRISSCRIHDLLHSLCVDLAKESNFFHTAHDAFGDPGNVARLRRITFYSDNVMIEFFRSNPKLEKLRVLFCFAKDPSIFSHMAYFDFKLLHTLVVVMSQSFQAYVTIPSKFGNMTCLRYLRLEGNICGKLPNSIVKLTRLETIDIDRRSLIQPPSGVWESKHLRHLCYRDYGQACNSCFSISSFYPNIYSLHPNNLQTLMWIPDKFFEPRLLHRLINLRKLGILGVSNSTVKMLSIFSPVLKALEVLKLSFSSDPSEQIKLSSYPHIAKLHLNVNRTMALNSQSFPPNLIKLTLANFTVDRYILAVLKTFPKLRKLKMFICKYNEEKMDLSGEANGYSFPQLEVLHIHSPNGLSEVTCTDDVSMPKLKKLLLTGFHCRISLSERLKKLSK
The following text describes a protein:
Function:
Transporter required for vacuolar uptake of at least histidine and lysine.
Subcellular Localization:
Vacuole membrane; Multi-pass membrane protein.
Sequence:
MQTLDETSNLLPPPEEAEAPPLEQKFHEYNLALPKFPILFSLWLGSFLSSLDSTIVANIMNRVAEEFSESSKKQWIATSFLLTNTAFQPLYGKLSDITGRKSALLTAQFFFGLGCLLTCFARNVTEFSIARAICGIGAGGLNAISSIAVSDICTARERGVYQGYANIVFGFGQLLGAPLGGVFIETIGWRALFGIQVPVIMLCSVLAIKNINIKLFHVPPMKERYTLKNLSRIDIFGSLSLVATISGVLFLCSSQLNKLYLALFTIGSFIVFILVERYYATEKILPFELLTRSFCLSSAVTVISSFVVFGEIFRSPIYLQLLQNISVTKTGLFLIFPSISVAVGSLVTGWVLRNTKINLAHCAYQIIFGGMIMQLLGLGLGYFLLSHLNPDYTIYDMLESITFRSNSIWWKLIYVFASVLVSFGYACLLVATLVSIVFTVEKSQQGTMTGVFYLWRSIGNVLGASLTLVSYENSLSSMLWNYMFKTKRDDEYHFTKKQYYSLINDSSYLRGPNFPTDIFVRILDVYKKAFLISYIPNIALAAVGIVLSLYLVKHTYKRSSSS
The following text describes a protein:
Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MARRLRLFKEQMTKAGVSPSMWSTRDDHFDLEHLEVKLEELEAELLEINANNEKLQHTYNELLEYKLVLEKVGELFSSAKNKAVAHQKELEFQTTVEGSIDSPLLLEQEETTTKQIKLGFIGGLVHREKSIPFERIIFRAARGNLFLKQGVIEHPVLDPLSGEMVHKNVFVVFYSGERVKSKILKICDAFGANRYAFSNDSSKQFQTIREVSGRISELKATIDAALIHRSTLLQTIGYHHGQWRLLIHKVLQRATMDCSSQVVAIFQVLETTESPPTYFCTNKFTSSFQEIVDAYGIAKYQEANPGVYTVVTFPFLFAVMFGDWGHGICLLLAALYLMIRERKFASQKLGDIMEMAFGGRYIIMMMALFSIYTGDASTTGFIKVRSTYPFGVDPKCHGTRSELPFLNSLKMKMSILLGVSQMNLGIIMSYFNAKYFKNNINIWYQFVPQIIFLNSLFGYLSLLIIIKWSTGSQADLYHLMIYTFLSPTDDLGENQLFVGQKLLQLVLLLLAVVAVPWMLLPKPFLLKKQHQERHQGQSYDLLCGTDDTLESESQSIAHDHDEFDFSEVFVHQLIHTIEFVLGAVSNTASSLRFLAHSELSSVFYDKVLLLAWGYNNTIVLIIGIFVFICATVGVLLLMESPSAFLHALRLHWVEYQNKFYEGDGYKFFPFSFTLLTDEDEL
The following text describes a protein:
Function:
Probable oxidoreductase.
Sequence:
MSRKCEFLVVGGGIAGVSCAESLAIYRPNASILLLTESSIVKSVTNLVPVARYLHKFDVREQDVSEMGASFQTLVDRLDHINSREHCIRTKAGLEIKYRYLCLCTGGTPKLFSGKVVNPLVIGIRDTDSVQLLQRKLATAKDVLILGNGGIASELAYELKDVNVHWVVKDSHISATFVDPGAAEFFHIAMNECNAKDSSPVVAIKRMRYSEVLPKEQTNNHGAALGPDWHRSVDLSGAREGEENRLPKIYYKSRISSVQDLADDAGAIVKLEHEDGSFQQLTCDFIVSATGVWPNTDYTCDSPLQFSDDGGISVDEMMRTNLVDVFAAGDVCTANWPAAMHWFQMRLWTQARQMGSMAGRSMAAASEGESVYQDFCFELFGHVTKLFGYPVVLLGRFNGQDLGRDYEILVRCTRNKEYIKFVLQNGRLRGAMLIGNTDLAETCENLILNGIDLEPYGDDILNPDIDIEDYFD
The following text describes a protein:
Function:
Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus. Nucleus.
Sequence:
MAAAGAGTSGSGAGGAAAAALELPEDVQAQLSTFRQLLGDLKAALGAAAGAVPGGGAELAGAVPDSLERARLCLALAKSVNALHHVYVRAHGRDPFTPATAGGVAVGRQELDRIRQYDKKVNRAVSEAELRGSRRALELDVAAASRFIDAAMPELSQQQRAALKRAGQAANERRGLPERKPKKARGWAGGGGRAGGADQEGEEADEQEEERQEEEEQRQGPDADATADGGEGAATVAAAAAGEAEAAVAGASQGTARRSTRSRGGAAAAVTDNATAAPTPSKGNKARGKGMAAAGGDGGAAAAAAEQFLAGFAAKG
The following text describes a protein:
Function:
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability. Involved in the behavioral responses to anisole.
Miscellaneous:
MISCELLANEOUS: The atypical heteromeric and topological design of the odorant receptors appears to be an insect-specific solution for odor recognition, making the OR/Orco complex an attractive target for the development of highly selective insect repellents to disrupt olfactory-mediated host-seeking behaviors of insect disease vectors. Odor-evoked OR currents are independent of known G-protein-coupled second messenger pathways.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MYPRFLSRNYPLAKHLFFVTRYSFGLLGLRFGKEQSWLHLLWLVFNFVNLAHCCQAEFVFGWSHLRTSPVDAMDAFCPLACSFTTLFKLGWMWWRRQEVADLMDRIRLLIGEQEKREDSRRKVAQRSYYLMVTRCGMLVFTLGSITTGAFVLRSLWEMWVRRHQEFKFDMPFRMLFHDFAHRMPWFPVFYLYSTWSGQVTVYAFAGTDGFFFGFTLYMAFLLQALRYDIQDALKPIRDPSLRESKICCQRLADIVDRHNEIEKIVKEFSGIMAAPTFVHFVSASLVIATSVIDILLYSGYNIIRYVVYTFTVSSAIFLYCYGGTEMSTESLSLGEAAYSSAWYTWDRETRRRVFLIILRAQRPITVRVPFFAPSLPVFTSVIKFTGSIVALAKTIL
The following text describes a protein:
Function:
Transcription factor. Required, in concert with signal transducer and transcription factor sta-2, for up-regulation of the vacuolar H(+)-ATPase and acceleration of lysosome maturation at molt. Involved in regulating hypodermal development, perhaps acting downstream of transcription factor elt-1. Modulates environmentally induced changes in collagen gene expression, including rol-6, sqt-1, lon-3, and dpy-13. Involved in regulating expression of various genes, including gst-4, sod-3, ugt-9, and col-144. In response to oxidative stress, required to up-regulate expression of gst-4 mRNA. Regulated by the Insulin/IGF-1-like signaling (IIS) mediated pathway. Plays a role in longevity. May regulate the expression of genes that control sensitivity to osmotic stress, in conjunction with the GATA region-binding transcription factor elt-2. May form a transcriptional circuit with GATA factors egl-18 and elt-6.
Subcellular Localization:
Nucleus.
Sequence:
METANYYLPSPPYSSTSSSDSRESRMNTPIPTTYSEENVNSLFHLMPDNTDQWMTSQKNFWQEGSPSSSEYLHQQAVQPSQQARLPGISNFMKDSQLSVKPAAYYCSPTMNDYRVEKVANTLLDPYVQLDQPTYADFTNAQVLNHQQEMLQMNFPTPLSTSYMNTAQVTQTHQMPFNIFELNLSNFATFQPACDTPLPLLNSSPTHPYTTMSNFTPPPQDPLVAEPKPMKKRMAAVQCHQNSICSNCKTRETTLWRRNGEGGVECNACNLYFRKNNRKRPLSLRKDGIMKRNRRPRNESPNSAIRNTHQRHGHAAAC
The following text describes a protein:
Function:
DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). Mediates interstrand cross-link repair in response to replication stress: acts by mediating DNA glycosylase activity, cleaving one of the two N-glycosyl bonds comprising the interstrand cross-link, which avoids the formation of a double-strand break but generates an abasic site that is bypassed by translesion synthesis polymerases. In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MVEGPGCALNGEKIRAKVRPGQAVLDVRGSALQSLGGPALPRAASLAVVSSQAAALNDNKDSSQNFSRLLNGCVYCGVQTLGKELLMYFGPKALRIHFGMKGSIMINPLENKNKNGVSPVLEIQLTKDLICFFDSSVEFRNSAESQQRVRMMEELDVCSPKFSFSRAESEVKKQKGRMLCDVLMDQRVLPGVGNIIKNEALFDSGLHPAVKVCQLTDEQTHYLVKMIRDFSILFYRCRKTGSVISKHYKVYKRPNCCQCCCKITVCRLGENNRMTYFCPRCQKENPQQVDICSLPRRDTTIRWPSSRGDHVARKSEEQWACVVCTLLNRPSSKTCDACLTSRPTDLAIKNEDNSIDFTNLVKYPCNSFGKPSTEVKINRKTAFGTTTLVMVDFSNKSSGLERKTSQNQILDGEFQNPPRTNVCSSDDPLHPSKERTNRTPQPSDKVNVSPAVCAQSKLFSPAYKKLKTTHPSSLDLKSAHPGFSNSEPGINMTDGACVLNADSPRCSKHNRLCALRIVRKDGDNKGRRFYACSLPREAQCGFFQWADLSFPLCDHGKRSVMRTVLKIGPNNGKNFFVCPLEKAKQCNFFQWAENGPGIKIIPGC
The following text describes a protein:
Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Interacts with beta-1 and beta-2, but not with beta-3.
Subcellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side.
Sequence:
MSSGASVNALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPRSCALF
The following text describes a protein:
Function:
Catalyzes the oxidative denitrification of neutral nitroalkanes, including 3-nitro-2-pentanol, 1-nitropropane, 2-nitropropane, nitroethane and nitrocyclohexane, and may thereby protect the organism against toxic compounds. Has no detectable acyl-CoA dehydrogenase activity.
Sequence:
MVDFKLSPSQLEARRHAQAFANTVLTKASAEYSTQKDQLSRFQATRPFYREAVRHGLIKAQVPIPLGGTMESLVHESIILEELFAVEPATSITIVATALGLMPVILCDSPSLQEKFLKPFISGEGEPLASLMHSEPNGTANWLQKGGPGLQTTARKVGNEWVISGEKLWPSNSGGWDYKGADLACVVCRVSDDPSKPQDPNVDPATQIAVLLVTRETIANNKKDAYQILGEPELAGHITTSGPHTRFTEFHVPHENLLCTPGLKAQGLVETAFAMSAALVGAMAIGTARAAFEEALVFAKSDTRGGSKHIIEHQSVADKLIDCKIRLETSRLLVWKAVTTLEDEALEWKVKLEMAMQTKIYTTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPLFDGGNIGLRRRQMQRVMALEDYEPWAATYGSSKVDKSRL
The following text describes a protein:
Function:
Tyrosine kinase of the non-receptor type, phosphorylates the marelle protein. Required maternally for the establishment of the normal array of embryonic segments: involved in the control of pair-rule gene transcription in a stripe-specific manner. Together with Hsp83 and piwi, mediates canalization, also known as developmental robustness, likely via epigenetic silencing of existing genetic variants and suppression of transposon-induced new genetic variation.
Subcellular Localization:
Endomembrane system; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated.
Domain:
Possesses two phosphotransferase domains. The second one probably contains the catalytic domain (By similarity), while the presence of slight differences suggest a different role for domain 1 (By similarity).
Sequence:
MALANGGEDRMDDSSSGRTSLADSASLTNSSLRSGTSSQSIHTNDGTIRVFNFTTGEFERFHPNMLCEEICNTMCRQLGIAPIAQLLYGIREHSTSRRPSPLVRLDLTWCLPGERLNCQLVYCFRMRFRVPELDSQLELIDGRSHKFLYRQMRYDMRTEQIPEIRYPEHKDKSTGLAVMDMLIDDQEQSEDQQAMRSIEKLYKLYLPPSLWRAHSFFVGSKIREVFRSLKANSLSVERLKWHYVHQVSHLAPTYMTEQFTCTVQYLPNEEVARGSGPIGTSLAHSTSTLASSGSTNTLSTLTTNTNSVALGGSGKKAKRRSTSGGIDVYVRVFPHDSLEPGLKVARVTSEATLKWILVGAVEGIFMISKINDTSVRLEIVGLPKGYEMQFQTEKEMKSFISYLGIYIRLSSKWMQDLCHSYRTPSLEELSSLHCHGPIGGAYSLMKLHENGDKCGSYIVRECDREYNIYYIDINTKIMAKKTDQERCKTETFRIVRKDSQWKLSYNNGEHVLNSLHEVAHIIQADSPDRYRIPASKYDKPPLLLLLLPKNLKAKKTDLQLSEAELQRRNPQIFNPRTDLQWYPDSISLSDDGMMFTMRGDWIQQSPVKDVSVTMKMLKSDGNFMEFFRLAQTWSLIQSPQFLKLYGLTLADPYTMVMEYSRYGPLNKFLHSMPNVTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKYDPNSYVLDAKISDPGYPRPYRESDSPWIPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKEDLSTLRQEQLLRQKNLDGNILKMLDQDICPAPIFETIMDGWSDDETKRFSHHDIFSRLNTIKAEILPNYMPPPEIATNGTGDETVIDRSDIPFLPFPRSNMLMVIPLTSECRVIYNMENMIGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNTMQVSTDFHREIGIMRTLSHPNIVKFKYWAEKSHCIIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGLIHRDLAARNILVDHNGDGDCVKISDFGLAQFANSDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGVTLFEMFSRGEEPNLVPIQTSQEDFLNRLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSFATIVDIITREVATKVTHPTDGHQSPPNQPTDAE
The following text describes a protein:
Function:
Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction. Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG. Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8. Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
Subcellular Localization:
Cell membrane. Secreted.
Sequence:
MRLPKLLTLLLWYLAWLDLEFICTVLGAPDLGQRPQGTRPGLAKAEAKERPPLARNVFRPGGHSYGGGATNANARAKGGTGQKGGLTQPKKDEPKKLPPRPGGPEPKPGHPPQTRQATARTVTPKGQLPGGKAPPKAGSVPSSFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGGNSSVKLEAGLANTITSFIDKGQDDRGPVVRKQRYVFDISALEKNGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGRQPAALLDVRSVPGLDGSGWEVFDIWKLFRNFKNSAQLCLELEAWERGRAVDLRGLGFDRAARQVHEKALFLVFGRTKKRDLFFNEIKARSGQDDKTVYEYLFSQRRKRRAPLATRQGKRPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR
The following text describes a protein:
Function:
Probable DNA-binding protein which plays a role in protecting yeast cells against copper toxicity. May regulate the expression of important copper homeostatic genes.
Miscellaneous:
MISCELLANEOUS: Present with 521 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MNYNCEIQNRNSKNVDNQVSLPPIQVLFNSIEKRSMPELAFSNIEYSHGNLRSSTEEQNYPAPVLLPQHHSIAYPAINSGGTSTTATPTASTVETSKTSSSAMDTQSQYGSSKKSKSASDDAKPCYKSAPIYEIINKEKDAGAQYNRPFSDFVESKSRRKQNSGRRSNLPKETVQILNTWLLNHLNNPYPTQQEKRELLIKTGLTKIQLSNWFINVRRRKIFSDYYTLVNSIPNDNANNTPVERVQNVSAYHNTLSATNNTMYDATSTCSTDYELSKRFAHAPVTRRKKLIDRLEELKKLSNPDMN
The following text describes a protein:
Function:
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs. Required for the maintenance of dsRNA killer plasmid.
Miscellaneous:
MISCELLANEOUS: Present with 981 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MGKKRAPQKGKTVTKPQEIIVDESKLNWKPVDIPDTLDDFGGFYGLEEIDGVDVKVVDGKVTFVTKKDSKVLKDSNKEKVGDDQESVENESGSDSESELLEFKNLDDIKEGELSAASYSSSDEDEQGNIESSKLTDPSEDVDEDVDEDVLKENVFNKDINIDDISPVNLPEWTNLAPLSMTILQSLQNLNFLRPTEIQKKSIPVIMQGVDVMGKASTGSGKTLAYGIPIVEKLISNFSQKNKKPISLIFTPTRELAHQVTDHLKKICEPVLAKSQYSILSLTGGLSIQKQQRLLKYDNSGQIVIATPGRFLELLEKDNTLIKRFSKVNTLILDEADRLLQDGHFDEFEKIIKHLLVERRKNRENSEGSSKIWQTLIFSATFSIDLFDKLSSSRQVKDRRFKNNEDELNAVIQHLMSKIHFNSKPVIIDTNPESKVSSQIKESLIECPPLERDLYCYYFLTMFPGTTLIFCNAIDSVKKLTVYLNNLGIPAFQIHSSMTQKNRLKSLERFKQQSAKQKTINHSNPDSVQLSTVLIASDVAARGLDIPGVQHVIHYHLPRSTDIYIHRSGRTARAGSEGVSAMICSPQESMGPLRKLRKTLATKNSVSTDLNSRSTNRKPIKWQNTVPLLPIETDILSQLRERSRLAGELADHEIASNSLRKDDNWLKKAADELGIDVDSDEDDISKSNSDTFLLKNKNKKMQKTINKDKVKAMRATLNELLSVPIRKDRRQKYLTGGLVNLADNLVKKRGHNSIIGHEKTNALETLKKKKKRNN
The following text describes a protein:
Function:
Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
Sequence:
MQNQLSEKQELESLYEGSLSHIERGEIIKGKIMGVRNDGVIVDVGYKFEGIIPLNEFSEEELKNIKEADEIEVFIEKIDDAQGIISLSRDRALKIKGWEILMDAYEKALPVEVKITGKTKGGVLTSFYGINGFIPASLLEIRKPKNLDEYVGKTFKVKIEKIEPPKNLYGQWRNLKTSLILSRKAYLQEEKEKMKKEISEKIKEGLKIKGTVKNITNYGVFVDLGGLDGFLHISDISWGKVRHPSQFFEIGSEYEFIVLKADTENERITLGYKQKKADPWENIDKKYHPGMKVRGKVTRVEDFGLFVELEEGVEGLVHVSELDWIAPKHPTYYAEVDEWINVKVLDIDRENRKISLSFKQLKPKPWEVVAKKYKVGDRISGKVKTITDFGIFVRLPEGVDGLIHISDISWTKHIDHPSQIFKKGQKVDAVILSLEPEKEKLSLGIKQLSEDPWIKEIPEKFKIGEIYNAKVIKKTEHGLFVDIEGIVEGLVYNSEIDKNRTVKEGDEIKVIVVKVDKEKRKIGLSMKKIDENEE
The following text describes a protein:
Function:
Can use acetyl-CoA to synthesize acetate esters from various alcohols, producing ethyl acetate, isoamyl acetate, isobutyl acetate, butyl acetate, hexyl acetate, heptyl acetate and octyl acetate. ATF2 seems to play only a minor role in the acetate ester synthesis, compared to ATF1. Plays an active role in the detoxification hydroxysteroids and possibly certain phytochemicals, in association with the efflux pumps PDR5 and SNQ2.
Miscellaneous:
MISCELLANEOUS: Present with 3000 molecules/cell in log phase SD medium.
Subcellular Localization:
Lipid droplet. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Traffics to lipid droplets during the stationary phase.
Domain:
Segments of the N- and C-terminal domains (residues 19-36 and 515-532, respectively) are predicted to be amphipathic helices and are essential for endoplasmic reticulum membrane association.
Sequence:
MEDIEGYEPHITQELIDRGHARRMGHLENYFAVLSRQKMYSNFTVYAELNKGVNKRQLMLVLKVLLQKYSTLAHTIIPKHYPHHEAYYSSEEYLSKPFPQHDFIKVISHLEFDDLIMNNQPEYREVMEKISEQFKKDDFKVTNRLIELISPVIIPLGNPKRPNWRLICLPGKDTDGFETWKNFVYVTNHCGSDGVSGSNFFKDLALLFCKIEEKGFDYDEEFIEDQVIIDYDRDYTEISKLPKPITDRIDYKPALTSLPKFFLTTFIYEHCNFKTSSESTLTARYSPSSNANASYNYLLHFSTKQVEQIRAQIKKNVHDGCTLTPFIQACFLVALYRLDKLFTKSLLEYGFDVAIPSNARRFLPNDEELRDSYKYGSNVGGSHYAYLISSFDIPEGDNDKFWSLVEYYYDRFLESYDNGDHLIGLGVLQLDFIVENKNIDSLLANSYLHQQRGGAIISNTGLVSQDTTKPYYVRDLIFSQSAGALRFAFGLNVCSTNVNGMNMDMSVVQGTLRDRGEWESFCKLFYQTIGEFASL
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MLQKQVSTTTTMTTQELAMEGEKQLEETIEAAFQIISAMNDELCNPSLWSTSATPSSAATTTGSNGSALVSADAAAIDGTSHHSESAGGGGGGGSGNSVLDEASLRYKNSVTSLRAVLAAIPNSQKAKASEMQNGLGSPESEDEIEKLEEQALSLRMEIAKKNVHVKELIDKLRELIADISTWQSPCSV
The following text describes a protein:
Function:
Probably part of the binding-protein-dependent transport system YdhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINLALLIGLVSIAPMFWKILPHRGRYIAAWAVIYPLIVWWLMYGGFFALERVETRQWGGLTLTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVILFQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQYLEKRFNTGRTPH
The following text describes a protein:
Function:
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MYKLALFSLLSGASAFTAPSTGRTATSLNSLNGWQPDESAFAWGLPGAPAPFADGFDPLGFAANTDLATMKKWREAEAQHGRVAMLAAVGMLVTEEPIEYHPLFEAYNKDIGPAIRHLDEVRAVSPFFFEVLAIVIGTLELNRAVKGFKSPEGEFGFQDLNDEYYPGDVGFDPLGLKPKDADEFATMATKELQNGRLAMLGAAGMIAQELTNGEEIFVNLGLATDRFDPSTLPVQF
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKAKSGNRELFESLLRFPKRDVFDCVPLHYLVLKMSGMGCITPRAGVRNGSTMTTLIDIGLFVTNLILAVTMMIYGMFITQRHMQSPIMFIGLKMVNFTCYASTIYGLISCFINRHDIWKFYNEAYAVDNMLEELGERTNFTRSFALFVAYYGTAIGMCVLVIAVMYSENLPWMLLLNLGYSYFSLTTFHILSLTCLDVVRARNVRLNKVFRKQFSLEGDVADPPALTVYDPKQTLILRQIMQIFDKISDLADKGSYYYGIQIMVSIAGSFVYLMFYTFAFTLVIRSVLPAEIVFNAGPIISYSMFAYNVFIVAFYGNALKQQCAQLCFASTFDFVLVFGLISTLCESVKLTLLRMFLMQLGHRSPMITCGLFPFDWTLIFSILSTAATYIIILLQFESAGSSSG
The following text describes a protein:
Function:
Appears to have a role in the stabilization of the DNA polymerase delta complex.
Subcellular Localization:
Nucleus.
Sequence:
MKKRTTQAKKSGQNTNIRDVFPHVVRSNSSQSHIGKKVSSEQSPTPDVTITTKTLDERIKEDDELSKEVEEAWNQIMAERISEPIHCENITKVEFILHHFDTTARYGPYLGMTRMQRWKRAKNFNLNPPETVGKILMLEEADEENRKRESLFYDLQTIPG