lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of TORC1 complex, which is an essential cell growth regulator that controls plant development. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy.
Subcellular Localization:
Endosome.
Sequence:
MESVQTELISGDQNGNIRVWDLTANSCSCELVDTSMRSLTVMWDGSLVVAVNNKGTCYVWRLLRGTQGTNDRYGHTIDNDVLIVTETLHKRDFLRICMSSVDQYMWIHHLLHTFPSGGDFDEDEDDSDTEEEIEMKNEDEEATGKMETTTALPVSNGVVSFLASGILKQNEVNSKSSTKMESPILIPMTEYSFWTKWIWLEICSQVHPILTHPMGSALETPFLLSLRMSGDKVLLKLGQGVRRLGRGSNNKSNYDNINSKKHG
The following text describes a protein:
Function:
Plays a role in endocytosis and trafficking to the vacuole. Functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress.
Sequence:
MEVDIAPQFGAELKDGFKSVNAWVSGGISWLDDIQQFYRERSAIEKEYSAKLSALAKKYYEKKARKQSSLSVGDTPTVTPGSLERYDCLPLHSPNNKLTLAEFAGALVTQLADPLKTLATRYEELRKLHGDYAAKLEKERDSQYTELRKQKGKYDSVCQEVENRRKKSDGAFDHGKAKARNAFEQQQIEMRNVKNTYLISINVTNKQKEMYYHDTEYLKHLSAEIPRNNPLLDSMMFVRHNAGGWQEPGDFQFEPSPVWLDDGNLAVDDAATTFLRNVLTKTKASLGEHRRELDKKRKEVESAKAVRRNIREGKDKRDEVDVVRAVFAIQEAMHEIERQKVSAEVEVSTITSVVGDVSIGARNHNFKSQTFKIPTNCDLCGDRIWGLSAKGFDCKDCGYTCHSKCEMKVPADCPGEQTKEEKKKLKDERQKAAHTVTSTNGAATGSHAELPKLGRSDTINSMNTLSSGYSATAHRSVSGMSPAAAEDPPAEKKAPAPAPVPGARRNRMIAPPPAQYIKDDDDMPPPTPKSNEVKGRMLYGYEENGEGELTVPEGREVTILEPDGRSLSNLSPMFQILLGASLTRDYTDGSGWMKVRSGSKEGLVPTSYVEVLAATPPTTASTFSSSTRPDSTYSASSASTTNLHAAVAGKKKGPAVAPKRGAKKLKYVEALYDYTAQSDAEHSMAEGDRFVLINMEAGDGWADVERDGVVRSVPANYVQQV
The following text describes a protein:
Function:
Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAAEVDGPLKRVLVPILLPEKCYDQIFVQWDLLHVPCLKILLSKCLGLGIVAGSLLVKLPQVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSSWGEALFLMLQTVTIAFLVLHYRGQTVRGVAFLACYAVLLLMLLSPLTPLALVTLLQASNVPAVVVGRLIQAATNYRNGHTGQLSAITVFLLFGGSLARIFTSIQETGDPLLAGTFVVSSLCNGLIAAQLLFYWNAKPPHKKKKEH
The following text describes a protein:
Function:
Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (By similarity). Through transcriptional regulation may play a role in epithelial-mesenchymal transdifferentiation.
Subcellular Localization:
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Chromosome.
Sequence:
MTTLTRQDLNFGQVVADVLSEFLEVAVHLILYVREVYPIGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHHPVERFVFEITQPPLLSISSESLLSHVEQLLRAFILKISVCDAVLDNNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKGT
The following text describes a protein:
Function:
May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG).
Sequence:
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMTHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
The following text describes a protein:
Function:
Has a role in the nucleotide excision repair (NER) pathway. Acts in both transcription-coupled repair (TCR) which removes damage from the transcribed strand of active genes and in global genome repair (GGR) which removes damage in untranscribed DNA. Involved in the repair of UV-induced damages where it is involved in the removal of cyclobutane pyrimidine dimers (CPDs).
Subcellular Localization:
Nucleus.
Sequence:
MMSDEDNTYSDDEEWLDLDLGLPNNDIKTAPILNSSLLSSAVHGERLIQERPTHDFGDVEATVDRTVEKRSRLKITSVDRKIRLQIHQLHLLCLTYHLCTRNTWCDDNRLNYLVKYIPPGIRVSLHPSSQKSQMIRNKTFLHGLAGLVEVWKRKYKITTNGLRKPNYGLLQNNSLISESLSLEEFCKNSKLLSGSRDYGTQLFASILRNLNVPTRLVFSLQVLSFRFKGAINEASSHEIVPAWSQQMENDSSSDISESAHITSRFRKRRKIIQPSFSNLSHLDASDIVTEDTKLKVIDSPKPVFWVEAFNKAMQKWVCVDPFGDASVIGKYRRFEPASSDHLNQMTYVFAIEANGYVKDVTRKYCLHYYKILKNRVEIFPFGKAWMNRIFSKIGKPRDFYNDMDAIEDAELLRLEQSEGIPRNIQDLKDHPLFVLERHLKKNQAIKTGKSCGRINTKNGVELVYPRKYVSNGFSAEHWYRKGRIIKPGAQPLKHVKNGDKVLPLYDEEATQLYTPKPVVANIVPKNAYGNIDLYVPSMLPYGAYHCRKRCALAAAKFLEIDYAKAVVGFDFQRKYSKPKLEGVVVSKRYEEAIDLIAEEIDQEEKEAEARNVRKTCLLLWKRLITGLRIRQRVFEEYG
The following text describes a protein:
Function:
Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein. Membrane.
Sequence:
MASKTNPFTFLQQVRAEASKITWPSRRETMISTAMVLVMVIFAALFFFAADQLIGWLLSLVLNVGR
The following text describes a protein:
Function:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle. Nucleus.
Sequence:
MKFPWSHTTIVDMIKTDQKVEEKCHQVTTDIIAGKLNVAEFVEELGPALTHTDASVRAKGTTLLSNVLKDLPPDALQANQVELLCTFYIDRSLDHHTVTPMVLAGIEALTHMTNFPDGAAVRLLRALFERVPCQSQKKPERTLYFQMMLNLAERKVDELKAWGVDFVYGVIGAIEGERDPRNLLYLFERMPSFIRTFPMYHLAEEMFETFACYFPIDFHPNPNDPVAITRDALAEHLANCLCATPEMAEFAVPLLMEKLDSSLIMAKLDSLSLLRKCLELLEVAKLEEHHDELWTALKKELLPAGGTSAAEKELAEATYAAVQALAKNASTDEPSAKALLDKILLSVMGGLTDASSKQFEMSLRVELSCAQGSVYCAVYVIEKLIPMLLAQLNVDGHVETRVANVLVDALQRLCAVCAHWYCIDRLDPALVGQMHKKLIEVVLQEADGSEQKRSALLALAAVPEMVTSENRYVVYSAMVKILLTATEQPSKTIDAAQECLFSFAIRYQQEVKTVVLEKLITHDYAKAETSLVQLVFKTLGKFILYHGYMDKMVKFFLSKIFDPDNERLAIIAMDTLTDVVENGNSSQLGKAELYEQYKLLDRCFEYANDKLSSDCLHAMAQLIGAVVKQLPVEEQHQLILKRLPALRLQQRADLYLASGLLAYLDQSVPLVDHFENLVTDLSKLALETDDERVRDVCNRLLCSLFNRMPDDEHHRGVLKRLLKMIREELKKHNHQAVVILSWIGKGLIARGHSEAGEIVDDIADLLDHPTLGHIAALAFEILSIEFPQLHLPLLRNLFKQKLFVWVMKKLEQKVEQYAETHLKALAFVLAATPHTVLKMNLSKVGPLLLKCLAQTDDKTILEALTIVLRFTREQDPFVQDHLQTLIPLLLKLTLHQSSMKIRIGALECLLYVCKYPTFLLLPFKQSVLLALQKPLDDRKRLVRNAAVTTRLQWFVVGSAEDTKTDK
The following text describes a protein:
Function:
Involved in the digestion of the blood meal.
Subcellular Localization:
Secreted.
Sequence:
MKYCAAVVVLLALAVFGQSAFAEQVSYRDYKVYSIRVDTVEKHNVLKRWQDVRGVDFWDRAGYRVMIHPSLQEAFERFLNLNAFSYERIIEDVEATIEAERKYDQEYRRRKAASGRATVDFEHFWTNAEVNAYLDELAQTYPNLVRVATIGTTHEGRPIKSITISTNNGVAGSKPVVFIDGGIHAREWAGVMSVLYLIHELVEHSSSYADMLNKDWVIIPVANPDGYEFSHTDNRMWRKNRFPATILCTGIDLNRNWDYLWVFSSNACSDSYAGTTAFSELETQALDRVLKQYGSNIAVYLAVHTYGDMILYPYGHSWPFVPVANQAAHIALGEQARDAITAVGGPRYVVGNSAEILYTANGCSDDYVAGVIGARYAYTLELTGGGRNGFDLPATEIMAVATQTFQIYRTMANNA
The following text describes a protein:
Function:
The glycine cleavage system catalyzes the degradation of glycine.
Subcellular Localization:
Mitochondrion.
Sequence:
MQRIPRLGALMRGDVKQILERASVILKRSVRSASTLDRLLPVHDDFCSRHLGPREKDQKAMLQYMGLKNIAELIDRTVPSSIRLNREMKLDRPLREEELMERAQTIANMNQVWRSYIGMGYYNCLTPPTIMRNVFENPGWQYTPYQAEIAQGRLESLLNYQTMVTDLTGLDVANASLLDEGTAAAEAMGLCSRHTKRKRFYVSDKVHPQTLAVVQTRADALGIEVVVSDCASMDFSKKDFCGALFQYPDTEGSVQDFSELVQACHDAKARYLALAVCATDLLALTVLKPPGEFGADIAVGTSQRLGIPLNYGGPHAAFFATRNSLMRLMPGRVVGVTRDAEGGKAYRLALQTREQHIRRDKATSNICTAQALLANMSALYAVYHGPDGVRDIATRVHHSTLLLATGVAKGGHGVIHPDFFDTLKVSPASSLEAIRGRATEKRINLRYFEDGTIGISLDETVTERDLDDLLWVFGCQQKSADLAEELGDQPNRSILRSKHKRTSSFLQHAVFNTMNMTVASCRGTFFILKPLQFFFSFLQGSCTMKLNSTTEMMPSSLPNFANLHPFVPPDQARGYARLFEELEQDLCEITGYDRVCLQPNSGAQGEYAGLRAISSYFDARGEKHRKVCLIPMSAHGTNPASAHMAGMAVDPINMAKDGSIDVAHLKAKLDQHADKVACIMITYPSTNGIYEETIRDVCDLVHGAGAQVYLDGANMNAQVGICRPGDYGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFLPSHPVADPSVARGGDPRHSFGAVCAAPWGSSAILPISWAYIKMMGSRGLRRATEVAMLNANYMRKRLDAHYKVLYLGQNGFVAHEFILDMRDFKKTTGVEAMDVAKRLQDYGFHAPTVSFPVSGCLMVEPTESEDKQELDRFCDALI
The following text describes a protein:
Function:
Involved in nitrate transport.
Sequence:
MAAHNLLLASFLFSCFCGSSYGFILFSSLQKTLLLTASPTPGQVLKAGVDNITVTWGVNQTLPAGTDSAYKTIKVKLCYAPASQTDRAWRKTEDNLSKDKTCQVTIVSRPYAKNNQSFTWTVERDVPTATYFVRAYALNSEGAQVAYGQSTDAHKTTDLFEIQAITGRHVSLDIASVCFSAFSVLALFGFFANEKRNAKTTEAK
The following text describes a protein:
Function:
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Located at the polypeptide exit tunnel on the outside of the subunit.
Sequence:
MQVKSHKPSKQRKYLYNAPIHHRGKIMSAPLSEELKSKYGINSIPIRKGDRVKVMRGDYRGTEGEVISVDRKRYRIAVKGIVRRKADGTEVPVPIHPSKVVITKLYLKDEARKRLLERKGVKVEEIVEESE
The following text describes a protein:
Function:
Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
Subcellular Localization:
Nucleus, nucleolus. Nucleus, nucleoplasm.
Sequence:
MAKTLNEETIKKVIRQVEFYFSDSNLPKDGFLKKTVDESEDGLVSLALICSFSRMRYHLGLGASKQEEISDDTIQAVAEALKASSFLKISEDGKRVGRVTELSKPEEVIEQIDVRTIAASPLEYSVKLEDVESFFGQHGKVNSVRLPRHVADKRMFCGTALVEFASEEDAANVVKQNLVYEGVELELKPKKDFDVERANEEKEVEHNRPHLGPNSKNNAKPEPDYPKGLIIAFKLKRKSSTEQNGNHQAAAESASAPETEGNKETTKDNVKVTEEKVPEDKDEDNNEKGDEKDVENGSGETDVQNPEAIEKSVESPTEEDDQAPAEEKLSIAACKDNKDVVMREDLKSVFQKFGTVKFVDFTIGSESGYIRFENEGAAQKARAAGVLAEEGGLTVKNFIAALDPVTGDAEKEYWSMFRNNQDKRRDFNKGNRGRGGRHNRGGKHSRPRGNDSGGRPNKFQKVRT
The following text describes a protein:
Function:
The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLTAFARAFKTPDLRKKLLFTLGIIVVYRLGTHIPIPGVDYKNVQECVDQASGNQGLFGLVNMFSGGALLQITVFALGIMPYITASIILQLLTVVIPRLEALKKEGQAGTAKITQYTRYLTVALAILQGTGLVATARSGALFSGCTVAGQIVPDQAIFTTVVMVICMTAGTCVVMWLGELITDRGIGNGMSILMFISIAATFPSALWAIKKQGELADGWIEFGTVILVGLVMVGLVVFVEQAQRRIPVQYAKRMIGRRSYGGTSTYIPLKVNQAGVIPVIFASSLLYIPALIVQFSNSTAGWATWITKNLADTAATPHIILYFFLIVFFAFFYVAISFNPEEVADNMKKYGGFIPGIRAGRPTAEYLSYVLNRITWPGSLYLGLIALVPTMALAGFGANQNFPFGGTSILIIVGVGLETVKQIESQLQQRNYEGFLR
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MMAYIGFILSIMFVISFVGFSSKPSPIYGGLVLIMSGGFGCGIVMSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEVWVSSAAVLGAFVLGVLMEVVLVLYVYKNGEVEVVFNFSGVGDWAVSDNGGFGVFSEEIVGVSALYSYGVWIIIVTGWSLFVGVLVILEITRGA
The following text describes a protein:
Function:
Broad specificity dipeptide epimerase. Catalyzes the epimerization of L-Ala-L-Ala, L-Ala-L-Glu, L-Ala-L-Ser, L-Ala-L-Thr and L-Ala-L-Met (in vitro).
Miscellaneous:
MISCELLANEOUS: Part of a large, functionally divergent protein family. Protein modeling and substrate docking were used to predict the substrate specificity, prior to biochemical analysis.
Sequence:
MQISLKKYTLELKHTFSISRESHDFQDTLIAGLTLNGKTGYGEATSNPYYKITAESMIKEIEGIKNEIESFEFTTPESFHSFLEEKELSNFAICALDLAAHDLYGKLLGKPLYEIWGTNNDQYPTTNYTIGIAELDTMVAKMKEKPWPIYKIKLGTDNDVAIIRELRKHTTATFRIDANCAWSAEETIANAPQLKELGVEFLEQPLQADDWAGMEKVMHQCVLPVIADESCIVESDVEKCGLHFNGINIKLTKCGGLTPALRMIKKAKLMGLKVMVGCMTESSVGISAIAQLLPQLDYVDMDGAILLKRDIANGVRIGEDGSVVFPTLGGSGVTLNQ
The following text describes a protein:
Function:
Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Binds RNAs which might negatively affect its histone methyltransferase activity (By similarity). COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face (By similarity). Set1-dependent trimethylation regulates chromatin changes at active promoters that ensure optimal RNA polymerase II release into productive elongation, thereby contributing to optimal transcription.
Subcellular Localization:
Nucleus. Chromosome. Note=Colocalizes with di- and trimethylated H3 'Lys-4' and with phosphorylated RNA polymerase II at transcriptional puffs on polytene chromosomes.
Sequence:
MQDVRNINLVNNSSNSHDSSLANSKMPRNFKLLSDPQLVKCGTRLYRYDGLMPGDPSYPTITPRDPRNPLIRIRARAVEPLMLLIPRFVIDSDYVGQPPAVEVTIVNLNDNIDKQFLASMLDKCGTSDEINIYHHPITNKHLGIARIVFDSTKGARQFVEKYNQKSVMGKILDVFCDPFGATLKKSLESLTNSVAGKQLIGPKVTPQWTFQQAALEDTEFIHGYPEKNGEHIKDIYTTQTNHEIPNRSRDRNWNRDKERERDRHFKERSRHSSERSYDRDRGMRENVGTSIRRRRTFYRRRSSDISPEDSRDILIMTRERSRDSDSRPRDYCRSRERESFRDRKRSHEKGRDQPREKREHYYNSSKDREYRGRDRDRSAEIDQRDRGSLKYCSRYSLHEYIETDVRRSSNTISSYYSASSLPIASHGFNSCSFPSIENIKTWSDRRAWTAFQPDFHPVQPPPPPPEEIDNWDEEEHDKNSIVPTHYGCMAKLQPPVPSNVNFATKLQSVTQPNSDPGTVDLDTRIALIFKGKTFGNAPPFLQMDSSDSETDQGKPEVFSDVNSDSNNSENKKRSCEKNNKVLHQPNEASDISSDEELIGKKDKSKLSLICEKEVNDDNMSLSSLSSQEDPIQTKEGAEYKSIMSSYMYSHSNQNPFYYHASGYGHYLSGIPSESASRLFSNGAYVHSEYLKAVASFNFDSFSKPYDYNKGALSDQNDGIRQKVKQVIGYIVEELKQILKRDVNKRMIEITAFKHFETWWDEHTSKARSKPLFEKADSTVNTPLNCIKDTSYNEKNPDINLLINAHREVADFQSYSSIGLRAAMPKLPSFRRIRKHPSPIPTKRNFLERDLSDQEEMVQRSDSDKEDSNVEISDTARSKIKGPVPIQESDSKSHTSGLNSKRKGSASSFFSSSSSSTSSEAEYEAIDCVEKARTSEEDSPRGYGQRNLNQRTTTIRNRNLVGTMDVINVRNLCSGSNEFKKENVTKRTKKNIYSDTDEDNDRTLFPALKEKNISTILSDLEEISKDSCIGLDENGIEPTILRKIPNTPKLNEECRRSLTPVPPPGYNEEEIKKKVDCKQKPSFEYDRIYSDSEEEKEYQERRKRNTEYMAQMEREFLEEQEKRIEKSLDKNLQSPNNIVKNNNSPRNKNDETRKTAISQTRSCFESASKVDTTLVNIISVENDINEFGPHEEGDVLTNGCNKMYTNSKGKTKRTQSPVYSEGGSSQASQASQVALEHCYSLPPHSVSLGDYPSGKVNETKNILKREAENIAIVSQMTRTGPGRPRKDPICIQKKKRDLAPRMSNVKSKMTPNGDEWPDLAHKNVHFVPCDMYKTRDQNEEMVILYTFLTKGIDAEDINFIKMSYLDHLHKEPYAMFLNNTHWVDHCTTDRAFWPPPSKKRRKDDELIRHKTGCARTEGFYKLDVREKAKHKYHYAKANTEDSFNEDRSDEPTALTNHHHNKLISKMQGISREARSNQRRLLTAFGSMGESELLKFNQLKFRKKQLKFAKSAIHDWGLFAMEPIAADEMVIEYVGQMIRPVVADLRETKYEAIGIGSSYLFRIDMETIIDATKCGNLARFINHSCNPNCYAKVITIESEKKIVIYSKQPIGINEEITYDYKFPLEDEKIPCLCGAQGCRGTLN
The following text describes a protein:
Function:
Binds preferentially DNA with A/T-rich content.
Sequence:
MASTSCFFNNNEFPMKVVAPMSHSYPEPLAKYDDVVANPKLFMLTLEKLHASMGTKFMVPIIGGKELDLCRLFIEVTSRGGIEKLMKERRWKEVTAAFSFPSTATNASFVLRKYYSSLLYHYEQIYYFRSKRWTPASSDALQNQSTMSVPASITQFLQPSPGTHPVDFQKSGVNASELPQVSSSGSSLAGVIDGKFESGYLVSVSVGSETLKGVLYESPQSIKINNNNIASAALGVQRRRRRRKKSEIKRRDPAHPKPNRSGYNFFFAEQHARLKLLNQTMDKDISRMIGELWNNLKESEKTVYQEKAIKDKERYQAEMEDYRDKMKTSIVTDNAGPLQQRFPEGDSALVDVDIKMHDSCQTPEESSSGESDYVADDINMDASSGGARVDSEAFVDSDKATKEGVIEVLSHCEGEVNAGGIQQTQKMNESQNMLSLL
The following text describes a protein:
Function:
Part of the yfcOPQRSUV fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes.
Miscellaneous:
MISCELLANEOUS: The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.
Subcellular Localization:
Fimbrium.
Sequence:
MNKSMIQSGGYVLLAGLILAMSSTLFAADNNLHFSGNLLSKSCALVVDGQYLAEVRFPTVSRQDLNVAGQSARVPVVFKLKDCKGPAGYNVKVTLTGVEDSEQPGFLALDTSSTAQGVGIGMEKTDGMQVAINNTNGATFALTNGNNDINFRAWLQAKSGRDVTIGEFTASLTATFEYI
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MKIEDGIEDELQMLQDPEPIFEEWAVDEALESNMITEENIKNIKPFFQTKRKRTNRPATVTACQVCGLELKYPSRMKEHMRTHTGEKPFSCDQCGKRFSQNTPYMHHYRAQHLGDFPFTCGFGCGRRFVSNARKNAHELRHRGEKRQGPPRPHLKPDKKMICPQLESQSILIDNGGLAMSASSIFVAPPDLSTGYDTPSTSTATSRSLHYAPQRSKSSLNFPLEDDGLPIDEEELTEKELESNARIDDVISTVLQKVLNVPHPHDETQTVETDKVPKKRAYAKTRLATIAQCGVCGLYLKHPSKIAEHIRTHTGEKPYQCGECGLMLSKASSLKTHIKRMHTAERTVQCTWCNATFVNDSVRKEHEMAVHAGVKRYTCIVKGCNAVFARRCYMMRHRRNVHPELFTPIFDNEEVNAEEEIDPVLGGPKYDYVYEEADPPMVVLTMEEIKMMNEFDEEEFVEQGGAIG
The following text describes a protein:
Function:
Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source.
Sequence:
MLVISANEQRNLVNMNEVIEYAALALKEFSAERTITPIRGSLPFANEQNTALIMPSVAEGLEALGVKIVTVVPQNKQIGKKTINGIVMLSDFQAGEPLALLEGSYLTMIRTGALSGVATKYLARHNAKTLCIIGTGEQAKGIAEAIFAVRDIEKVILYNRTEEKAYAFAQYIQEKFGKPAYVYKDPNEAVREADIIVTTTNATTPVFSEILQKGVHVNAVGSFRPSMQELPSHAIAKANKVVVESKEAALDETGDLQVPIKEGLFKANAIHAELGQIISGEKAGRENDEEITIFKSVGLAVVDIIVAKYLYERALEQGVGNKIEF
The following text describes a protein:
Function:
Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction.
Sequence:
MGQRQAKQHMQAGVKLYHQRHYAQAINKWRQSLNRLNNAEDRFITLGYLAQALCDQGEYEGMLSYALSQMQLATDQNDSAMKCEAFLNLAKAYERLADFTKALQYGKASLEHPSMDPRTPGYAHLTIALAHLGMSQFQQCLESFESAMNVANETSDRLLELQICVGLGSLFTLLRDITKALIFLRNALAIVQSVTVDDVHAKYRCLILYHLSVALRMKGSLVDAKEACDEASQLAVEMGNRAIHARCMCSLADIYRELGESEAKETITKSWARYEDAYRVMRGANDKMGEVLVLSSMAKSASESRSHYTGQCECQAIQLNKKCIEIANQIGCKHVVLKCHLRLAELYSQLNDDDSEETARRAASRLTQEMQLFCNFCGQRYGLKDESLQALRCSHIFHEKCLHTYLLQRTDQTCPKCRCRAVLSDNISIRSSIASTIDVQSPSTSFAPPGGVATPLVSAAAELGDITPQATLTRRSQQDKILRGAEKDIDRVDRSLARLKSQQSAAANACSAVAVPSPEVPSTTASCASEPILTASTTSQSHTHSNANHKPPPPPRKPCCSQAALPPSSIVALPPAMPLAEDGPLVITHTPTVTDV
The following text describes a protein:
Function:
Probable ATP-binding RNA helicase. Required for 18S rRNA synthesis. May play a role in restructuring of the pre-rRNA.
Miscellaneous:
MISCELLANEOUS: Present with 2000 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MGTYRKRFNEKARSGHMAKLKELKRIRNKQFTRQDENDERVENPDSAPAESSTTEPNANAEILEPLTEEEKKMKKRKLQELFTPKESKVSRLKKKRLDKFIEHQLKREERKTIIGKLQDYKIDTSLLTSSKRLGEGRQTKKEEFKEALSLERQGRGNEQTNEILYEEYEPKVWDEYGEGGSSEDDDGEDDFEASFGSMPKPTDNEEKKSSGFIDHRPAKFGGSGLSFGFSNIKVINKESKTPKKKYNWRQRVEMEELKKHGKEDEMDFDTTSEDDDEEEDQEEEDKMHPSENPLEEVESADSETGSEKFDQNDVANEFKDWANQEIKKLEGRDQELVTPTLNIDYKPIIRKEDLDDGLQEAYVPINENSTRKAFYVEVSRSDEIQKARIQLPVFGEEHKIMEAIHHNDVVIICGETGSGKTTQVPQFLYEAGFGAEDSPDYPGMVGITQPRRVAAVSMAERVANELGDHGHKVGYQIRFDSTAKEDTKVKFMTDGVLLREMMHDFKLTKYSSIIIDEAHERNINTDILIGMLSRCVRLRAKLHKENPIEHKKLKLIIMSATLRVSDFSENKTLFPIAPPVLQVDARQFPVSIHFNRRTAFNYTDEAFRKTCKIHQKLPPGAILVFLTGQQEITHMVKRLRKEFPFKKNSKYNKDLETPVSKMGINSKTTDLEAEDIDFSVQVIDQDKFKSAIRYEEDEGNSGNGEDEEDEEEEGFEEVLTEGQTANDPLYVLPLYSLLPTKEQMRVFQKPPQGSRLCIVATNVAETSLTIPGVRYVVDSGRSKERKYNESNGVQSFEVGWVSKASANQRSGRAGRTGPGHCYRLYSSAVFEHDFEQFSKPEILRMPVESIVLQMKSMAIHNIINFPFPTPPDRVALSKAIQLLQYLGALDNKEMITEDGKKMSLFPLSPRFSKMLLVSDEKACLPYIVAIVSALSVGDPFINEFELGINEISRKPNPDENLDDKIREHDESTPGMDPELKKELRSKFYKSRSQFSKLDKFSDVFRLLSVVSAMDYVPKEQKEIFMKKNFLRGKLMEEIVKLRKQLMYIIKSNTSKENIAVVIRNEDLKSDIPSVIQIKLLKQMICAGFVDHVAVRADVLFPDDAKITNRTSIINIPYIPVLATRTPNIEDCFVYIHPTSILNNLGEMPPKYMLYYSLHLGGNNKTRMNTLCDIASTPLANIARKGLLLTYSKPLTGQGLKTVNLSPTERYCYVVPRFGSTVDNDLKIGWDLNPIAVHQKKQKGQWTVIKFITRKGFQTITGEEKEKK
The following text describes a protein:
Function:
Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation. Also involved in androgen receptor transactivation. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. May play a role in the development of neuromuscular junction. May play a role in late myogenic differentiation. Also functions as part of the RQC trigger (RQT) complex that activates the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation.
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Nucleus.
Sequence:
MSDSLLRWTVDKLKHGFGLDASDDIVQYILSIDNADEIVEYVGDLLQGTEGNKQEFVDELVQRWQRCQTQTSDGLGGVLRKEVVMEELDTAPKDTQKKSKRKGRNKQEIVTVSQAEPEPVRTPIDLMKAQESSNSSSVKKKSKFVNLYAKEGKDKLAVLLPGRQACECLAQKHRLINNCLSCGRIVCEQEGSGPCLFCGSLVCTNEEQEILQRDSNKSQKLRKKLMGEGTEREYLPHQESKMKAGLEKAVKHKDKLLEFDKNSVKRTQVLDDESDYFATDSNQWLSPGEREALRKREEELRELRHASRKDRKITLDFAGRRVLDEGENLSPYYQKFDETVKAINTGSFGQKAKHSAPADRQHFRELVNPNILQSAPEWVDVASSNPSRKSSSKAASGKETSERSRLRLQDKELQEIADGGWCLSMHQPWASLLVKGIKRVEGRTWYTSHRGRLWIAAAANRPTPQEIAEVEAMYRHLYKHEPQFPAEYPTGCLLGCVNVSDCLSQEQFREQYPQISEESTSPFVFICSNPQELVVKFPMKGKHKIWKLESQSHQSAKKCLMQPA
The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MCFESVLIPMFLIIGIWGARERKIHAAYQFFLYTLLGSLFMLLAILVIYFEVGSTDYQVLAVADISETRQRILWLGFFLSFAVKVPMIPFHIWLPEAHVEASLAGSIILAGILLKLAGYGFLRYSIGILPDASAFFTPLVYSLAVISIIYSSFTTLRQIDLKKIIAYSSVGHMNITLLGLFSNTIQGIEGSLILMLAHGVVSPALFICVVILYDRYHTRLLKYYRGLTQHMPVWSVMFFLFTLGNIAVPLSANFVGEFMTFTGAYQQNPVLTVLGGLGMILSAAYGIWLYNRTAFGAQTAAKILGAGLATIGLAGAGVGVGLVFAALINSTSRNPSLRPQLFSYTILGTTGPVGPPGSIRPTLPVSWIPGLMLPYFIGSYREGRNESFSYGIDSSSVWDHYDLTGAYATGLGLAGSPAYEKGEIEETLLDNVMRRYLGPPEESSDSGSDSGDEDISNYISNYTHDDSSPRRFLGLIRYRYTQDTGQTEGNLGVEALNERAILHHLDNDHPLIGDGPLFERRLILNPPRDPHGFNLDVDQDSLSNTGSEDSNSSDPDSRGGSPPEGVEPPSSPRSGSFSTIID
The following text describes a protein:
Function:
Metalloaminopeptidase that catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Contributes to the degradation of bradykinin.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MAPKVTSELLRQLRQAMRNSEYVAEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIITEEHAAMWTDGRYFLQAAKQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLVPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKEKVADLRLKMAERSIAWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIVGLETIMLFIDGDRVDAPGVKQHLLLDLGLEAEYRIQVLPYKSILSELKALCADLSPREKVWVSDKASYAVSEAIPKDHRCCMPYTPICIAKAVKNSAESDGMRRAHIKDAVALCELFNWLEQEVPKGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPAKTKYNFNNRGSLTFEPLTLVPIQTKMIDVNALTDKECDWLNSYHQTCRDVVGKELQSQGRQEALEWLIRETEPVSRQH
The following text describes a protein:
Function:
Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MVVQGWQVFTRYVLNDSPSWTEPVTLLLLSTALSLAAAAGVHTNRHFGFYLLGEHMPPLVRRVFDVIRPVMIIAIGAVLAWWSAVLLLDGLDIKMAGAQMPQSINYLPLSIGGALMVVFALYKLWRVLRPIHTGGVR
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MASREEIFSKVKSIISEKLGVDESQVTEEAKLIDDLGADSLDLVDLVMDFESEFGVKVDDADLEKISTVGDIVSYIEKKLG