lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
Subcellular Localization:
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Domain:
Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
Sequence:
MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAVVLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFFPSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETLFVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDFLEQLRQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTMKERAKPEIIKGSRKRRIAAGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGFPGR
The following text describes a protein:
Function:
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKSVASKLLLGFGLVCAGLVLFGLLTFYNILSLEKIVADTANINRAIVELAINQAGVLVAVQNKDKSLLSSSVEGLRTSLDDIKAYQSDFSGENLKLLQESIAHLEEMIRITDSLIVDGVDQSIYDRFVELQAEIRNPLRKLVQNLGVENVSMTKNIKRNIIFFLVVVCAAAMFIAIFTTRNLTTPLKKLAVLVENLSHGVLNVEIEKIRSKDEIGKAAMAVEKLREILLDIITGINKASSEVSSSSEELSATSEELSANVNSISEALVSLNKEADENSATLEEFTASIEELSSTADSNSKSAQAMLESTQRVHEQVEKSTERIREITEKAHSTREMSENTKQALNRLLSMAENINSIVDTINSIAEQTNLLALNAAIEAARAGEAGRGFAVVADEIRKLAEESKAATQQIGEILGKLRDEINNSSKIVESTASAIEETASLVESIKDVFESIRIAMEDVQSRVESVAASTQEQSASLEELSAGVTRLTELLNKTRENTSSANSALQEANAALEELSASAQSLAELAQELQRRIEFFKI
The following text describes a protein:
Function:
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
Subcellular Localization:
Cytoplasm. Nucleus, nucleolus.
Sequence:
MTTETGIPEVVKASSETMSADGKPEKPNPSMFPKRQKRDTPKEYSYLRCEYKLPHKNHRQCHMQRKAEEKFCAQHVLLQKDSYAGRERVVCPVDPGHTVWADELQQHMYKCNKVKERMQKEREGWHRDDMNISNPEAKPCVGKKSDITVDYAKWIPVVEAAFKDVEEVPVEILNHEKGLAKRMTEVQNKKHALQQASLIAHMEKTGLLKSSSRILEFGAGRAELSRYINYAICAERQQDDKTAANYLFIDRAMPRMKMDGKLVKDTKDDFPEQPLPLIKRLKMDIKDLMLDGVPVEGPYDANLIVSKHLCGCATDLTLQCLLNSAVFTKEARPAALVIALCCRQICNVQMFPKAGIEWLQERGFDDDGFAALTRMTSWVLCGERPKKEPVEGEQTEAADNETPAPVGHPSGLPAEARKVIGLKCRRLLDQGRLHALRKEGLDARLVQYTEMDISPENVCLIVNK
The following text describes a protein:
Function:
Involved in negative regulation of early and late embryonic Notch signaling.
Sequence:
MHKNGNNGPVIDTKWHYLGPDSEKYGPYMSKDMLFWLQAGYFNDGLQLKTENEPNYHTLGEWSQLLGTHPFSMPVHSLDATIAQMNSMRPHGAMMMVPPGLQNQFQPPMPMRFPPFLPMPLLHQMNQNGPPMGAQMHSQPPSEPIDAGSLSHTPDSENETRLNEQTLQQPPSWLIALGLAGHGRKPHHHQQILAHQHIPQMQHANVATDQVVMKSVECQTEPVEISKEQASRVLSELLGQMVIIN
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MSSYFVNPLYSKYKAAAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAGFPHAHPQAHAHPHPSPPPSGPGCGGGGGPGQDYFHPGGGSPAAAYQAAPPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGPTN
The following text describes a protein:
Function:
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
Subcellular Localization:
Cell membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein.
Sequence:
MGGEKTGSQDDVARLPVDDVTCDVTSGEEFVVVDETEPKEEGDSSKHPSRDASPSNQEVEEPKKKKKKKRVRGLDLPVQVFKSRSERDPEFINQDLRVNFDDVIAEPEGYYTPKYSWHLSKEVYGFSKGCCYSVASFFCSVPAAFLWGIWFAFIACLNIWLLVPFRRCHNIKMSLWKGFWGVTVSSIFDPIFQSIGMVFNNMRVQTDKYEV
The following text describes a protein:
Function:
Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Preferentially hydrolyzes nucleoside 5'-triphosphates, with substrate preference for UTP > GTP > CTP. Hydrolyzes ATP and nucleoside diphosphates only to a minor extent.
Subcellular Localization:
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Sequence:
MARISFSYLCPASWYFTVPTVSPFLRQRVAFLGLFFISCLLLLMLIIDFRHWSASLPRDRQYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCRAMLSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWMYQVLHEGFHFPYDYPNLRTAQLVYGREVQWTLGAILYKTRFLPLRDLRQEGVRQAHGSWFRLSFVYNHYLFFACILVVLLAIVLYLLRLRRIHHRQTRASAPLDLLWLEEVVPMMGVQVGP
The following text describes a protein:
Function:
Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Localization:
Nucleus.
Sequence:
MAENQNGCSLEDCHTNLFALADLSGIKWRRLNAQSDTSYTADPLDDPVLVSYSKCVQADLLCVWRRQPKNANNSHHSSSSGPGLGGSNRSPMNGANSMACPKELWLFWYGDEPSSLQSFISSDLFEVESGSWESGPLSYECRTLLFKAFHNLIERCLLAQNFARVGKWFVQPYNNTDQLNKDSAHLSMSFNFFLHGDSTVCVSVDVRRHEALFSLTHTVLSAAQHITVVLLAPYGLSGTLTGKIYSDSEARSMQMMEDWKKYVMVFIMEMCVDECEGDEGSQFFYCKYETGVRLRYPSNFVLMTSDVNAAVLKRMSTVSSSSANTSNVSNNNVGANNFCNNLATGALQQQQQVDSKRSLLLQWNYSAKVIEKSWRDLVVANGQVAHGQSQGSEDHALYNATNNIVWNFGDVTQRSNCHCPKSRTQKPALSSSKLSQPPSTSLMSSAPSSLTSLNKSSLGGFGGGSLSSWKQQQQASNNNNNSNNNYNSKAEGRVRAHKACTPYHKRHANFTHKLLSSTSSSLLTSSSLSLTTSTASSTISLLSQATLSQQLMSSLEANSFTLPMNFGWKNASSSSSMPASLLTSTSTAFGGSNRGGIVNVHNGSVMPGVDQQNNNNSQILPAVTQLSSSSATSSATATNVNSMASKSLLHQITSGLDSSPHSAAPSPLMVTPNAQGSTVNQNGSDPTMPTLSPQPPTKSGGSVEVGGRSILNSGRSITTGKDGHIGSVADGAVSDGVHNGNNDSNNGINVAGNVNYKKTVGGSSSGGLGSTTASNGSALATSILYTCSVDDYKSKYESLADSSVKSELLSRVRPADVGKTWIKQQNRKRSRSISQQNIVGTVPKKPMLMCQFPGEDDEEMKIPSLIVQPNFKLPNQGFICSATNPSNVSDQSFWTVVGEASGREDSLHTQHRHSNFSLIPGGSNSPFSGYQDDRYNNNNRDSVLPKIKKEDNQGSDFFGGMDDSRNAMDYSSSPITLSSSKNDFAATTAPGHNLPLQQQQQQQQQTQQQHQLGLSSSFTRQSTNVMPMSSIATLMRENDLKPNIQDLDKMFDTDEEIEPDSPNRPESIRDESMATAFKSTSLSTNFTQGKFLFNLMTFATFLFVYCYCLTVKDLSRMFPTPPSADNPCSEPSPMMEIDSHHDYGQQQQHCQQQQQQHSQQQQLLHQQLLLQHSTSSASFSPLINSSMANVSQSLINLRKECSSLYKIPLISRIPMSADYNPIQLPNTLSIPLNASNLVYKSSAPQPAVSSSSSTSLQPPFSSLIPSSSSFAYRQQQQQHQQLQHQQQQQRMNIGGMTGVIGGKVVGAGFMINNGRTPLSYDMLSPASNSSINRRPAGSVDSRVASSLEPINSLMVNVMISDSVLNLFKDHNFDSCTLCACNRNIDGSDIGIYARTSSDALVPSVLSSIEGIYGLKSGLFYEDEVEISGYYHTGLDNIRKPPLIKRHSSNNNNNNMNNNNNNNNSNNTNNVNNNNSNVGNSEENALSDDGITADIISIIREQFSTQFPTMPIQNLFKSEYSRFISRSNCGSGSNSGSNCGSSSGGCGDGKNKSVVGGVSVEEPVDLEMKDCSDACFLALEYCKFLSMENNNNSSSNNNNNNVGGGCNSQLSSSSSLLVDRSKVCLHEWSFRHELAPLPSSSLEVVRLLKQLQPLLQDAIQKKRSTRLWESVYTISGPLTWKDFHLLAGRGSKETSEPKSIPYLMVGYDKELLNISPHSIKYWDKLMLEPLCEPRDVLYLVVSPENDVVIDQVSNFFNDFSIMYEQCRLGKHRVLYDKLRDGIIRVGRKNEEPLRDVVIDDWYNNIDNIIVKNLNEKRQVYRDAAKIHSASGGSRFTISNPDQPPFTLYSTSTSSSSSLPNVMNLPPVPQHSFSQTISNPLAGINSNPNNNNNNNNNNGPVDSSMSGVFGGEKMDFSMNAGSNNLNSMSNNDNDGTNSSHQLQDGSGGGGYGSDFLHNNNLSHEVVVAGQMPYVVVYIVDSFNYTSPSNNTNNGSNDDDDDGSFSARMVMMSLLRGFNNMVKMMPEKLQPYVKLQIVPQDMIMDSCQRQTTSYMKNLCFSVYTSCRRQLSHHNMEKSLTGFGPTSSANKIIKKLNSTYQQLQHQGVISNNGAGAGGAGTNGGPGSGSLLGNVSANSVVSFGNNNGLITSAGNVIIINSTIASTLLYSPPFILAPPLFQSTSILSPENYKEPLEKCGVLLCAYCLSEDQRFLLASLVDSTGELLETTCINIDIGDRKVRRRATVRRFAFHKLWEFILGTVACTARPWRLVVGRFGRLGHGELKGWSMILSKRNLQSSCLMLRRICQTCNIPSANQCPSILSACLVSTEIHPSIHIMVDAVKKEENQSSKRQLSTPKDASCTHILVYPTSATAQATDPNSASDTHMDFTATELLNEEELLNGFDPEDPDMINDFWTNLDNSPERIIDDENHDDPSSIQSRGTFLGGSNIEHEENNNLNLLQQPQAMGFYVSTAPPGPLPDWFWSSCPQRHDHCPVCLKASLHLHCPMVQQNQDDLIHQSSNHKKSTHPLDSYLTCDVLRYVLETYNALSWLTIDPSTNDRRTCLPVHMLILMQLYHAVKAYL
The following text describes a protein:
Function:
Has no esterase activity.
Subcellular Localization:
Secreted.
Sequence:
MWLPALVLATLAASAAWAGHLSSPPLVDTLHGKVLGKFVSLEGFAQPVAVFLGIPFAKPPLGPLRFTLPQPAEPWNFVKNATSYPPMFTQDPKAGQLISELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPGSVTIFGGSVGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEVGLRLVRLRLDTPTSLALCS
The following text describes a protein:
Function:
Subunit of the chromatin-remodeling complex (DDR complex) that mediates RNA polymerases IV and V (Pol IV and Pol V) recruitment to chromatin. Cooperates with Pol IV and Pol V to regulates RNA- and RNAi- (RNA interference) directed non-CpG de novo DNA methylation on cytosine of genes targeted for silencing and enhancers, also known as siRNA-directed DNA methylation (RdDM), thus leading to epigenetic modification of the genome and promoting/maintaining heterochromatin. In collaboration with Pol V, mediates/maintains, in cis, methylation-associated self-silencing of exogenous transgene transcribing inverted-repeat (exo-IR) silencer (exo-Pdsi) to restrain exo-IR dsRNA accumulation and subsequent inappropriate silencing of active protein-coding genes (e.g. PDS) by exo-IR-derivating 24-nt siRNAs. Also required to mediate loss of CpG methylation when the silencing inducer is withdrawn. Required for the maintenance of retrotransposon large terminal repeats (LTRs) and transposable elements (TE) edges silencing mediated by cytosine methylation. Required for transcriptional repression of specific classes of pericentromeric 180-bp repeats by promoting condensation and histone H3 lysine 9 dimethylation (H3K9me2) at chromocenters. Required for basal resistance against the necrotrophic fungal pathogen Plectosphaerella cucumerina.
Subcellular Localization:
Nucleus. Note=Excluded from the nucleolus. Colocalizes with endogenous repeat loci.
Sequence:
MGFVYIVMTGYYKNVHKRKQNQVDDGPEAKRVKSSAKVIDYSNPFAVSNMLEALDSGKFGSVSKELEEIADMRMDLVKRSIWLYPSLAYTVFEAEKTMDNQQVVEGVINLDDDDDDDTDVEKKALCVVPSSSEIVLLDSDDEDNERQRPMYQFQSTLVQHQKNQGDVTPLIPQCSFEEVDLGRGKEMPSAIKAIVEGQTSRGKVLPIENGVVNEKGVYVGVEEDDSDNESEAADEDLGNIWNEMALSIECSKDVARETSHKEKADVVEDCEHSFILKDDMGYVCRVCGVIEKSILEIIDVQFTKAKRNTRTYASETRTKRFGESDNELKFSEEGLMIGGLAAHPTHAAEMKPHQIEGFQFLCSNLVADDPGGCIMAHAPGSGKTFMIISFMQSFLAKYPQAKPLVVLPKGILPTWKKEFVRWQVEDIPLLDFYSAKAENRAQQLSILKQWMEKKSILFLGYQQFSTIVCDDTTDSLSCQEILLKVPSILILDEGHTPRNEDTNLLQSLAQVQTPRKVVLSGTLYQNHVKEVFNILNLVRPKFLKLDTSKSAVKRILAYTPCDVRGRLTGSNSDMASMFNETVEHTLQKSEDFTVKIKVIQDLREMTKKVLHYYKGDFLDELPGLADFTVVLNLSPKQLNEVKKLRREKRKFKVSAVGSAIYLHPKLKVFSDKSDDVSDTTMDEMVEKLDLNEGVKAKFFLNLINLCDSAGEKLLVFSQYLIPLKFLERLAALAKGWKLGKEVFVLTGNTSSEQREWSMETFNSSPDAKIFFGSIKACGEGISLVGASRILILDVPLNPSVTRQAIGRAFRPGQKKMVHAYRLIAGSSPEEEDHNTCFKKEVISKMWFEWNEYCGYQNFEVETIDVDEAGDTFLESPALREDIRVLYKR
The following text describes a protein:
Function:
This promotes the activity of RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MSLVENLFLEPQSKRRKINPETIESPSPNCNHWFVRNKICISCYTTVDNFEGRSFDYLYKGMQMSNEALGFTKGLISQTSWLEDKKLHLVLDLDQTLIHTIKTSLLYESEKYIIEEVESRKDIKRFNTGFPEESLIKLRPFVHQFLKECNEMFSMYVYTKGGYDYARLVLEMIDPDKFYFGNRVITRRESPGFKTLDLVLADERGIVIVDDTSSVWPHDKKNLLQIARYKYFGDKSCLFSEDKKKIDESDEKGPLNTALRFLKDVHEEFFYDWSKKDLDSVDVRPLLKEISLRWKRKADGVV
The following text describes a protein:
Function:
Involved in the biosynthesis of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of the rhamnosyl moiety from dTDP-rhamnosyl (dTDP-Rha) onto the decaprenyl-pyrophosphoryl-GlcNAc (C50-PP-GlcNAc), yielding rhamnosyl-decaprenyl-pyrophosphoryl-GlcNAc (Rha-C50-PP-GlcNAc).
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Sequence:
MTDVLPVVAVTYSPGPHLERFLASLSLATERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANLGYGTAVNRTIAQLGEMAGDAGEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALGPLIRDPDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTTAYRQERLEPSERPVGWLSGSCLLVRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKAHSTGRDPASHLAAHHKSTYIFLADRHSGWWRAPLRWTLRGSLALRSHLMVRSSLRRSRRRKLKLVEGRH
The following text describes a protein:
Function:
Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.
Sequence:
MADHGERNAVAAPFSSLAVRSSTEWVADHASHVSIDPAGIAKVVDSLHGDLPAVSWDFEGIHYFDGGPLTAQYLLVLDTLNFCFWPDGDLHYDHLAAGLKRALQRDNSIFDAKSLKSFTGIQLRELLEWPRPLPLEDERARLLAEVGTELERSFDGQAVNLILAASGSAVALVELVAMHFPGFRDHSVYKGHQVFLYKRAQIFVADLWGAFKGQGLGAFADIAAITMFADYIVPAVLRQWGILNYSPKLARIVDNLEELSSGTEEEIEIRACTIAAVEMLREKLRSKAGKERMHKLVLDQSDLRYSLQCRGSAYHPARPPVL
The following text describes a protein:
Function:
As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
Miscellaneous:
MISCELLANEOUS: In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.
Subcellular Localization:
Nucleus.
Sequence:
MPAVLPIKLNPSQMRPVAYRIFSKKHGLNLKSTGLETLTEIIGKNYGTEWRGAEAAKMMEEICRLWKEQEMGVFVEGKPLQELFDEITASKKAKEKARVQVVSKSVGLTGVEEIEDREGEPQVNVIREAAPSVDVVWKEFFKVISAFDQPLFHYNARQQRFEKRKTKPTLFANAQSASNMFLTRYHLVYNRLLRNDDTTDLKITSIRSLIGRQGEFSIFGMLSKNPEQKICLQDDTGRILLILAAGCKPDPGVYYPEGSFVICNGRYMKSGDAEVFVVITMGPPVAEKRQETITAYGNMDYLGLHGNPHGSVVRRIERQVEASMLAEEKRLVDQKVIVFGGDMYLDNPLTLKALQKVFSTIELEFQDSGTKKPLAMVFSGDFTSQYQPPHLYKKGFDKLEELFKEFSSIITGVKIIFVPGQRDPWTNTFPTQNAVVPLQPLPTTMINRVARLCGEDVSMSSNPCRMAYLTQDMVFYRDGLSERLRKCNLQLDSAKDDSDDSDDDIEIDNDEVMINDVVVNEPESSFDFGEGLSNLTRPVDISTPMASQVGPTNTLSAKEVESRKIVRTICDQGHLSPFNRHDRPVAWDYDETLWLSPLPTILFMVDTHAPKFSLRYEECMVVNPGPFLNRKIASWVEYDPSKKTVKERQLHI
The following text describes a protein:
Function:
Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
Sequence:
MCGKTILLEVTPCDNFVFNKSTNLTDTAYVTLKNISEKPVCFKVKTSVPNMYVSRPNPDLLKPGEARQLSVKFRSSDKVSLNAKSYKLKIESCEFESEDIDDLKSFWSSIPNEKILVHKSPIILGTGSSPDFRNDQIASESSRQSSPIQNVSDDGKSSHHSTAKQLQENNENSKSLKYTKQLVEVPLGENQQADQTGTTCDKKDEFQKKNQLEVEIKFVDKIHEIKSQLEDSFELKLKEMEMRLEEKFEKRISRLTQFMETISLSNSPGNSRRVFELDDNFSIVAKKELEQMRQDFEKVLDGQNKIAEEKMNELRKRREELQRESDELRTMEEQLGITERIFWAN
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MTEALKRDYRICEEIGRGRFGVVRRCEPLEPSAAPSSAAPSLAVKSIDKSAVSGDDLDSHCLLTEPKVMSLLSPHPNLLRIHNAYEDSSHLHLVLDLCDSPDLHRAVASSGPLPEPEAARILAQLMRAVAHCHRHGVVHRDIKPENILFDSRGRLRLADFGSAEVIGGGEQAAALRGVVGTPHYVAPEVVAGREYGEKVDVWSAGVVLYVMLAGFPPFRGESAVEIFGAVLRANLRFPPRVFRSVSAAAKDLLRMMLCRDASRRLSADQVLKHPWVTSYEGAQATELVI
The following text describes a protein:
Function:
Lipolytic acyl hydrolase (LAH).
Domain:
The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
Sequence:
MGNGSSSGSGRDDQGFATILSIDGGGVRGIVPSVVLTALEAKLQKLDVDNKDARIADYFDFVAGTSTGGLMTAMLTTPNAEKRPTFAAKDIVQFYLDKSQLIFPQTTEQYEDDELFDDEAAINSVLDEARNQIQQYKNEMRNHIIVDPLISVLRFLLNWGLLPNFIRKKLRSLVFPRYDGVKLHEIINEEVGQKLLSDALTNVIIPTFDIKLFQPIIFSSLKAQRDKSTDARIADVCIGTSAAPYYFPPYYFKTKVDFNLADGGLAANNPSLLAVCEVMKEQKMDGRKLLILSLGTGAADQSGRYVVGDPSKWGLLRWLWYSENNGSPLIDILTTAPDEMISTYISTIFKYCGWEDNYYRLQAKMELTGARMDDASQENLKKLEKIGKDLAAKHDAELEALAQKLIKNRKARLARTSG
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MRHLTATSRRRRLGATRTCASWAGCSPRPSTTSRAVRGTRRRPSTAVRRRSAPSSHLVARLRRYEAWHRRCGPGSPLFGEAVEHLRSGRNAARSECQYAVWTPFNGLGNRMLALASTLLYALLTDRVLLVHAPQEFDGLFCEPFPGSSWTLPAGFPIADFDATFTMLSPTSYKNMKKAGTINGGDRVNVTAEGLPAYVFLDLIQSYTDAAFCEADQRVLAKFNWMVVKSDVYFATALFLMPAYRRELARLFPEKEAAFHHLARYLFHPSNDVWGIVREFYEAYLAGADECVGLQVRVFQEVPVPFETMYGQIMRCSEQEGLLPKVALAQQNAAAARNTSAVPPPDGRKTKVTSILVTSLSPEYYERIRGVYHANWTETGDYVVVHQPSHDGVQHTEARGHNQRALAEIYLLSFCDRIVTTAVSTFGYVAHGLAGVRSWVLLRSPSPETRAEPACVRSSTVEPCMQAAPRQMCGAAKGSDIGGLAPYVRHCEDVHGGVKLFS
The following text describes a protein:
Function:
In kidney, has anti-inflammatory and anti-fibrotic properties by limiting the induction of chemokines, fibronectin and collagen expression in response to TGB1 and pro-inflammatory stimuli.
Subcellular Localization:
Secreted.
Sequence:
MPKRAHWGALSVVLILLWGHPRVALACPHPCACYVPSEVHCTFRSLASVPAGIAKHVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLDYFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGNPWTCDCEMRWFLEWDAKSRGILKCKKDKAYEGGQLCAMCFSPKKLYKHEIHKLKDMTCLKPSIESPLRQNRSRSIEEEQEQEEDGGSQLILEKFQLPQWSISLNMTDEHGNMVNLVCDIKKPMDVYKIHLNQTDPPDIDINATVALDFECPMTRENYEKLWKLIAYYSEVPVKLHRELMLSKDPRVSYQYRQDADEEALYYTGVRAQILAEPEWVMQPSIDIQLNRRQSTAKKVLLSYYTQYSQTISTKDTRQARGRSWVMIEPSGAVQRDQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWLRIKSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQPAEKDTVTIGKNPGESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQGADHFTVGITVTKKGSGLPSKRGRRPGAKALSRVREDIVEDEGGSGMGDEENTSRRLLHPKDQEVFLKTKDDAINGDKKAKKGRRKLKLWKHSEKEPETNVAEGRRVFESRRRINMANKQINPERWADILAKVRGKNLPKGTEVPPLIKTTSPPSLSLEVTPPFPAISPPSASPVQTVTSAEESSADVPLLGEEEHVLGTISSASMGLEHNHNGVILVEPEVTSTPLEEVVDDLSEKTEEITSTEGDLKGTAAPTLISEPYEPSPTLHTLDTVYEKPTHEETATEGWSAADVGSSPEPTSSEYEPPLDAVSLAESEPMQYFDPDLETKSQPDEDKMKEDTFAHLTPTPTIWVNDSSTSQLFEDSTIGEPGVPGQSHLQGLTDNIHLVKSSLSTQDTLLIKKGMKEMSQTLQGGNMLEGDPTHSRSSESEGQESKSITLPDSTLGIMSSMSPVKKPAETTVGTLLDKDTTTATTTPRQKVAPSSTMSTHPSRRRPNGRRRLRPNKFRHRHKQTPPTTFAPSETFSTQPTQAPDIKISSQVESSLVPTAWVDNTVNTPKQLEMEKNAEPTSKGTPRRKHGKRPNKHRYTPSTVSSRASGSKPSPSPENKHRNIVTPSSETILLPRTVSLKTEGPYDSLDYMTTTRKIYSSYPKVQETLPVTYKPTSDGKEIKDDVATNVDKHKSDILVTGESITNAIPTSRSLVSTMGEFKEESSPVGFPGTPTWNPSRTAQPGRLQTGIPVTTSGENLTDPPLLKELEDVDFTSEFLSSLTVSTPFHQEEAGSSTTLSSIKVEVASSQAETTTLDQDHLETTVAILLSETRPQNHTPTAARMKEPASSSPSTILMSLGQTTTTKPALPSPRISQASRDSKENVFLNYVGNPETEATPVNNEGTQHMSGPNELSTPSSDQDAFNLSTKLELEKQVFGSRSLPRGPDSQRQDGRVHASHQLTRVPAKPILPTATVRLPEMSTQSASRYFVTSQSPRHWTNKPEITTYPSGALPENKQFTTPRLSSTTIPLPLHMSKPSIPSKFTDRRTDQFNGYSKVFGNNNIPEARNPVGKPPSPRIPHYSNGRLPFFTNKTLSFPQLGVTRRPQIPTSPAPVMRERKVIPGSYNRIHSHSTFHLDFGPPAPPLLHTPQTTGSPSTNLQNIPMVSSTQSSISFITSSVQSSGSFHQSSSKFFAGGPPASKFWSLGEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVEGRITLHENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHVF
The following text describes a protein:
Function:
Involved in the transport of copper.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MMHMSFYWGTSVTILFDGWRTSGWPGYLASLLALFLAAALYQHLEARRVRLRAGRRHRAGGGGGAASSAAGPVVPAASDARALLSAAGGRLGLGLGLGRRWMKEPRAAASAAAAALFGLSAAVGYLLMLAVMSFNGGVFLAVVAGLAAGHLAFRGGADEADGGVGDDELESPCACA
The following text describes a protein:
Function:
Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine.
Subcellular Localization:
Cytoplasm.
Sequence:
MEENICRKLFPIQHRPPALSKVALQGVLKDLLGTDIGISSVYEFCSFCDRNYHIHIDHDKFKHYLESKDLQLQDDQFKQNQQKPSFVLKILNPCYLEYYELTLARLKLLQYLHNCGIRCPKILPLHNGNIMKIVRLSDEKVKNQAESMELIAYILIFIEGQTIAKIHSNFDLCYRLGRFAAEIDIKLQAYSDETIKQANNIWSLQNFPACKYYLKYCSDEKRGFLENIFNQICRTYFNKHVKNLRTAIIHADFNHGNIIVKYNNETNNYDINGIIDFGLVNYSCVVFELAVLMAYTLLTVPHDRIRALGHLISGFHSVFPLTEVEYKSIYTLIILRLVQTSILTKYSSNLQPDNEFTMDSYEEKLEILKFLLSIPERDVYAVWDKIVGFSVGEDVYNYLESENIQI
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil.
Sequence:
MMREFVVPESANGFRIDLFLTQSCDGYSRSQIRDAVQNDGAEVDGRIIRPSYKVKAGQKVRFRVPPPASDDTVPENIPLDILYEDDGLVVINKPAGMVVHPARGNWTGTLTSALAFRFQSLSDVGGPTRPGIVHRLDRDTSGVIVVAKNNAVHLNLAAQWHDRLVQKEYTAITFGRLDRDRDWIHASIGRHPYQRDKQAIREGHATSKTASTFYEVVERHGRVTRVDVRPKTGRTHQIRVHLAHIGCPILCDRLYGGHSELSRSQIRRLAGTEVATPGVKPTPEGEEILLSRQALHAKALTFTNPQTGKEMTLTAPLPPDLQAVLDLLSSDSSL
The following text describes a protein:
Function:
Involved in starch metabolism in endosperm. Acts as a modifier of SUGARY1 (SU1), an isoamylase starch-debranching enzyme involved in amylopectin biosynthesis in endosperm.
Sequence:
MIRPAPWVGAGHRGRGGEAGACTESLGSESGDVGCDAAEIDQFFPPAPAAGGPDDAGAEPCIPDLAAAAAAGKRRRGGFPPPMPRASGPLFLRAERRGGRLILTEVRADERERRVVFRAERDGGRLRLRFANDGDGPEAAGGGGGAGGGGGELCQVAAGRRGVQVGAVMMGAI
The following text describes a protein:
Function:
Sodium-phosphate symporter.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTSLATTLASLPATLADGVAGVGEIGMSSHSLLILMIMGGIIAFILAFAIGANDTANSFGTSVGSKVVTLYQAYMLASFFETLGAVLIGHKVTDTMRKGVIDIDQYENKTAELLYGQISILSGCGAWMLLATFFKLPVSTTHSIVGATIGFSLVVSGTSGIHWHKILRIFASWIVSPLLSGVVSICFFVLVDHLVLRKSNPLRSGLLVLPFLYLIAVAFNIFAIVYEGSEFLHFNELPLWTVVLLSLGAGVLVAVIVALFVGPYLRKKIIAESSVDCAPSTANSVELGSVCAQSKAALLEYEHKQAKLSGVSNGSHAANAVAPSASLPKEPTFFRSHKPEDPQAAKLFSFLQVMTACFGGFAHGGNDVSNAIAPLVSLWAIYWEGTSKQEMHTPWYLLFYGAFGMCVGLWLLGHRVIYTVGENLTKITPPSGFAIEFGAAVTVLLASKMGLPISSTQCKVGSVVAVGLAQASHSVRWHTFRNICLSWIVTLPVAGLLSAMVMMMFRYFAL
The following text describes a protein:
Function:
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.
Sequence:
CSTPKKTLFDDNFVEMKSPAIGKFLVEAVEPPMICESPSAIDRRRIFGRETSSSNLPMSPMSFSPKNLLTKQIIHQNAPTSLMNKQPMKRNSLVPKKLSLDEINVRKNFLKRDNPHLNKFRKCHSKVETVKKYLDEEDENANLIADFSAPYILPLIEGGKQSDLKAISHDTLSDVLLGKYDDCMNSFTIIDCRYPYEYNGGHIIGAKNFYTKDSIFNEFISSNINLSSTNKEKNILIFYCEFSSERGPKMCRYLRNEDREWNQENYPRLFHPEIYLLENGYKEFFNNHRGLCEPSSYKPMLHEDNADDLIRYKAESKMYVDRFEKRSNSRVLSR
The following text describes a protein:
Function:
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Sequence:
MSNSDFKGQIVVYSIVGCPFCMRAKQTLRDLELPFLDINLDSYGESVRKEVRERSGRSTVPQIFFNSKHVGGYDDLKALLADKVGLDRLIEEVKNNESPPEAPKVPDSSELKKEKIGDMDFTCELDEHAVLIRDLKMSGIIKDHRKGLTTHKNTFQANQFVDWLVKEKSFDDRATGIVSGQDLLDRGYAAAVKATRDGRFEDNDTLYRLLEHDQNSALNAGLTSECEARPASDLGEDLRKLILSLYNDFLTPDGKSVNYKGIAESSQFKMYTRMTAQLYRVDIKSATREEKIAFFINIYNALVIHGYVAVGAPTNLWQRYKFFNYVSYIIGGQLYSLNDIENGVLRANRKPIGSLSKPFSKSDLRLVVALDQPEPLIHFALVCGAKSCPPIKTYSGKDVMNELKLAAEAFLEGSDGCQVNADKKEVKCSQIFKWYREDFGKNDKDVAVFISNHMGPGEKKTSFLQVISQKDYKVSYMKYNWAINSQ