lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
Subcellular Localization:
Periplasm.
Sequence:
QXGDLVAAGKKVYRQCHACHSVGEGAKNRVGPEQNNLFGRVAGSLPDFRYSKAMKSAGENGLVWTDKSLHEYLKNPRAYVPKTKMIFAGLKKPEDIDAVVAYLKTFDTDGMPDPDASTYTPPNG
The following text describes a protein:
Function:
Supports initiation of fatty acid biosynthesis in the absence of FabH.
Miscellaneous:
MISCELLANEOUS: Overexpression rescues altered fatty acid profile, growth defect and reduced cell size of the fabH deletion mutant.
Sequence:
MSQLPGLSRETRESIAMYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAHHQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGVKRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQLQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWGLIWLMLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQMQVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE
The following text describes a protein:
Function:
Transcription factor, master regulator of tracheal cell fates in the embryo, necessary for the development of the salivary gland duct, Malpighian tubules and the posterior spiracles. It may induce a general fate of branched tubular structures of epithelial origin. Functions with tgo to regulate expression of btl.
Miscellaneous:
MISCELLANEOUS: Readthrough of the terminator UGA may occur between the codons for 958-Ser and 960-Val.
Subcellular Localization:
Nucleus.
Sequence:
MLPYQAAVAMDYAGYQRQPTPGHPGSHMATMGSLGMPAVPFTHSWMVPTQDLCAMPPYNKMTGHQQPPGAGMHAQQQPLEPGILELRKEKSRDAARSRRGKENYEFYELAKMLPLPAAITSQLDKASIIRLTISYLKLRDFSGHGDPPWTREASSSSKLKSAAIRRSPAVDLFEQHQGTHILQSLDGFALAVAADGRFLYISETVSIYLGLSQVEMTGSSIFDYIHQADHSEIADQLGLSLTSGGGGGGGSSSSGGGGGGAGGGMASPTSGASDDGSGTHGTNNPDVAASMTQASTSGYKGYDRSFCVRMKSTLTKRGCHFKSSGYRASDATSNCNNGNNASNNAKNVKNPGSNYSVVLLLCKLRPQYTFSHSRKSQPPLLGMVALAIALPPPSVHEIRLECDMFVTRVNFDLRVAHCEPRVSDLLDYSPEDLVNKSLYSLCHAEDANRLRKSHSDLIEKGQVLTGYYRLMNKSGGYTWLQTCATVVCSTKNADEQNIICVNYVISNRENENMILDCCQLEPSPDSIKHEEGLGNDKSSGSPGGDASGEGNSHLSAGDMKLNSPKTDSEGHSHRGRGRSAAASHGSSMNSLTMIKDSPTPLGVEIDSGVLPTTVATPVPAATPPVQSTKRKRKTKASQHAEDQGQEQVISEQPLPKLPTMEQRDQQPRSRLPSIVDEQPSSAADSAVKDLEQAMSKHLPSPAAVVSVAPPNTDFSADSLLKQQQQQQQLDPNEKSSTIQWIGTPYQQPPAPMPATALLRQLYANRESVIRATARQTPTGVGPGVFYGDQQTGPLPTPPGSESSYENQYLQLHSAASGGHPGGQKTSADAFTNLVSTYGGYHSSIDYHNAMTPPSSVSPRDSNQPGKAAPVLASNGGYDYAPDPLRGQYATSSGDVVPATLPLKPQASYTATMHPSGSTTTEGGVTYSNLDQPQYFAPHSSFHLYHKGSPASGWYSTPSXVVDDQGQVPPSCQDQYHHHHHHHHHQDGSAGSSASQASERWDFVGALGKVARMFFSARKGNPG
The following text describes a protein:
Function:
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
Sequence:
MLSSYFSWMEHVDARVLRAGGTSDNHMRPLYLPYEAPPLLRVEPVCTLRDHTDRIWCVAWCPTANVVASCSGDGTVRLWGYMLNVGREEIPNGRDQNGTWSCIYTLEGEHSRTVRHVSWSPSGTFIACASFDRTASVWRRVSDDPNCFEFELEAILDGHENEVKCAAWGTDNTLATCSRDRTVWVWDRVDVGEFECAGVLAGHAQDVKACAWLFPSGGVEKPLLFSCSYDNTVKVWTESHKRDDWYCHQTLTRHDGTVWSVAVQPIEQPIDSLQMEEEEREGTALEYSPVVCCSSDDKTVTFWSRDGDGNFRSVCTASGFAERTIYSVGWAPSGSDVSPAIVACGSGDNKVTLLGVYQSRGYEEVHVSVVAEVPSAHEADVNTVAFSRSTNELWGDNSRGGEGLLLASGGDDNIVRIWRVTAAL
The following text describes a protein:
Function:
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MVQPSPAPVVTITPAPAPAAPSHPHGWKRKQEFKALHLALAFLTTLPLPHVRDVQPGDFARASAYYPLAGYAVGGLVAGLLYLNVPLPPGVVAALGVGLWLGLTGMLHFDGLVDSADALFAMKSPEQRLDILKDVHVGAFGLATGVLALLLLWSLLGAGLPWYAPLVAAVVARMVVLMPMNAYPAARQESLGAQSRQGRWGLAFLFALPALLLPHAWLAALVALLGVTLVAAWAARRLGGGLSGDVYGLLIVVAELLVLGFYGWGFTPL
The following text describes a protein:
Function:
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Sequence:
MSRLFNNFLLKTNKNQFIQSFSTKSQINNNIFNNLIKNEKISLPPPPFLSSSSPLSMNNIFNRNNKNLYTTNNFNYNKLQFTTQSPNPTPTPTPTPTPTPTPNNNENNNNKNNNNNNFKEEQKKILQEKNKAIGLYVLIAIIGILGLSYAAVPLYRIFCRATGYGGTTRDADDFDVIRKRNLDRTVYPIKVTFSASTANKIPWTFKPTQSTIECLPGEPVLCFYRATNNTDTPIIGVATYNITPMKAGTYFTKIQCFCFDEQRINAHETIDMPVLFVIEPELLDDKNMKGVSDITLSYTFFKSNDQGEYEEI
The following text describes a protein:
Function:
Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10.
Subcellular Localization:
[Isoform 1]: Secreted. Nucleus. Note=May also be nuclear when following receptor (CCR10)-mediated internalization; [Isoform 2]: Nucleus.
Sequence:
MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN
The following text describes a protein:
Function:
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MVRIRRKFAFILCGVTLFVFLILYVVLNYSVPERARVQDISYLENKIKQLENGLSKHRQEFGDIRKQIDTIRGAVDGGDDAYADSKILDKAPLLGDREMMKESVINANGGGAGTCALRTDIIPQPDVQMLNLYEQVSFENIDGGVWKQGWPIKYHPSEWNSHHKLHVFVVPHSHNDPGWIQTFDEYYERSTKNIFANMLRHLDENAGMRFIWAEISYFAQWYDKLAAEQKDIVKRLVKKRQLEFVTGGWVMPDEANSHWYSMLLQLTEGQTWLQTRLNVTPVSSWSIDPFGQSATMPYILKQSGFENLLIQRTHYIVKKNLALKKQLEFRWRQLWDTRGDTDLFTHMMPFYSYDVPHTCGPDPKICCQFDFKRLPSMGLSCPWNVPPKPITDQNVAERAEMIVDQWRKKSVLYRTRNVLIPLGDDFRYTTSSEWEAQRVNFEQLFNYINNEPSLNVEAKFATLQDYFDAVRSTSGASGMEQFPSLTGDFFTYADVNQDYWSGYFTSRPYHKRQDRILLHYIRSAEMLHAWNVWEPDSDWKPLAERLEYARRQLSLFQHHDGITGTAKDHVMEDYAKRMSRAIEDCKFVMQQSVYRLLTKPSVYQPDPAFMYLSIDDSRTVNGSDNVRPTIILGEELPSKQVVLHNSLPYTRSEVVEFYVASPFVTVLDGNGGTVPSQIAPVWSWHTRPDSISQPQPSNTKYRLLFRANVPPLGLSVYTINSKNSAEESLGVTYTKVIILSKSPFTVNLAAGYPEDIDHASPTEMSLRFEEGGSTSAAFTSKGLLKSLTIENNQATVPVHLEFYRYGMQLSSGKSGAYLFHPAGNATLMTYDQPIVLVMKGPLETSITAGLPFAVHQTILRDDSVEIRNLVDIGQRDNTEIVMRLQTNINSGATFYTDLNGMQIIKRKRFQKLPIQANYYPVPSTMFIEDDNYRLTLLGGQPLGGSSLSSGEMEIMQDRRLTRDDDRGLGQGVQDNLPVLHLFRLVLESRESCTKPDPDYPTGFLTLPAHAQLQSLLHPLDKLIYNENDWTGVQMEGFGSRHEPLEQGLEVVAIRQLSHVHFGRTSGASPVGLIVHRTNFEDCGSEANMEGMLNIKKLLNLDDEHDIYSARLTLLKPLELVPSDDISLCPMDAKAYIVKR
The following text describes a protein:
Function:
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Sequence:
MIGNERHGLVGVIGADLIRNAKIPLILLVAVLISAVLVVTTAHRTRLLTAEREQLVLERDALDIEWRNLILEENALGDHSRVESIAIEKLKMQHVDPSQENIVIK
The following text describes a protein:
Function:
Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNVNHHHRLGPVPWTRTVWAENVDQELACLKECLKLYPKIAFDTEYPGIMHRTYLHSSDDDCYKTMKVNVESSKLIQCGFTLFNAKGEIGGVWEINFSNFGDPSDTRNENSIDFLKKHGVDLNKIRSEGVDMFKYNFFPKFLSALYSQKHVDHVEFVAFQGAYDFAYVLSILNYGKLPETRGEFASEVVRVFGEVYDLKVMAGYCDGLGEHLGLSKLAQLLNIPRVGRAHHAGSDSLMTALVFIKLRHVFEDSKFAKGMLYGIGKRMMVTATTTTTTMPSSVSMPMMCQQNLVSYPSSDMIFHNGYMPSYDHNNQVLFWNHLAVPWMSYDNGMYVDQLNHVPSSTFAYPYQTPYAADYLGQLPDLLQ
The following text describes a protein:
Function:
Major efflux pump for acriflavine and other quaternary ammonium compounds (QACs). Also required for resistance to methyl viologen (By similarity).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MFRQWLTLVIIVLVYIPVAIDATVLHVAAPTLSMTLGASGNELLWIIDIYSLVMAGMVLPMGALGDRIGFKRLLMLGGTLFGLASLAAAFSHTASWLIATRVLLAIGAAMIVPATLAGIRATFCEEKHRNMALGVWAAVGSGGAAFGPLIGGILLEHFYWGSVFLINVPIVLVVMGLTARYVPRQAGRRDQPLNLGHAVMLIIAILLLVYSAKTALKGHLSLWVISFTLLTGALLLGLFIRTQLATSRPMIDMRLFTHRIILSGVVMAMTAMITLVGFELLMAQELQFVHGLSPYEAGVFMLPVMVASGFSGPIAGVLVSRLGLRLVATGGMALSALSFYGLAMTDFSTQQWQAWGLMALLGFSAASALLASTSAIMAAAPAEKAAAAGAIETMAYELGAGLGIAIFGLLLSRSFSASIRLPAGLEAQEIARASSSMGEAVQLANSLPPTQGQAILDAARHAFIWSHSVALSSAGSMLLLLAVGMWFSLAKAQRR
The following text describes a protein:
Function:
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.
Sequence:
MAAAVAAAAAAAAAAASFQVLEMESMETAVAGSASLAAEVRGSGTVDFVTGAGISTLVDTGGGDPGPEAEDFECSTHCSELSWRQNEQRRQGLFCDITLCFGGAGGREFRAHRSVLAAATEYFTPLLSGQFSESRSGRVEMRKWSSEPGPEPDTVEAVIEYMYTGRIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNCVAIHSLAHMYTLSQLALKAADMIRRNFYKVIQDEEFYTLPFHLIRDWLSDLEITVDSEEVLFETVLKWVQRNAEERERYFEELFKLLRLSQMKPTYLTRHVKPERLVANNEVCVKLVAEAVERHALRAENIQSGTLQHPTSQVSLLPRYGQNMDVIMVIGGVSEGGDYLSECVGYFVDEDRWVNLPHIHNHLDGHAVAITESYVYVAGSMEPGFAKTVERYNPNLNTWEHVCSLMTRKHSFGLTEVKGKLYSIGGHGNFSPGFKDVTVYNPELDKWHNLESAPKILRDVKALAVEDRFVYIAARTPVDRDTEDGLKAVITCYDTETRQWQDVESLPLIDNYCFFQMSVVNSNFYQTASCCPKSYSLENEEAVRKIAGQVSDEILESLPPEVLSIEGAAICYYRDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPYRYLHGTQRYPMPQNLMWQKDRIRQMQEIHRHALNMRRVPSSQIEC
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MIRPGLIKSKNTGQEDSRLHSNKQDKIVNSRKEGKKGLEEESESFDGVDLTDLMDQVEEIKVKEEVEQENNIKGQHHNGFRRSSGGILVPSIDPSQNQNQMTIFCDGSVCVFDNITPDKAQAIMLIAAATTAASRTQIMNMTTPQSSQSSNALPATPHSQSHPAEPTSLSKLQRDLPIARRNSLQRFLEKRRERKLVNKSPYTFKKEPDSPGQSLATQL
The following text describes a protein:
Function:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. FOS has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Sequence:
MMLQHLGPSLADISCSALVPCLSPPGELTLEDFTNFTPIVKEELRQVIQNKRLSCGLSADASSDSASSASDQAPPTHESGVKRELTLEEHDRKKRRRERNKIAAAKCRSKKKEKTEGLQKESEKLESINADLKAQIEELKQQKQQLVYMLNLHRPTCIVRAQDGQTPEDERNLFLQHIKESNFQLHSLTSTTEGLLGGGPLSLDHICCPADL
The following text describes a protein:
Function:
Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3'-5' exonuclease activity. The gamma complex (gamma(3),delta,delta') is thought to load beta dimers onto DNA by binding ATP which alters the complex's conformation so it can bind beta sliding clamp dimers and open them at one interface. Primed DNA is recognized, ATP is hydrolyzed releasing the gamma complex and closing the beta sliding clamp ring around the primed DNA; [Isoform tau]: Serves as a scaffold to trimerize the core complex; [Isoform gamma]: Interacts with the delta and delta' subunits to transfer the beta subunit on the DNA. Interacts with ATP, drives ATP-induced conformational changes in the gamma complex that opens the beta sliding clamp ring. After loading of primed DNA ATP is hydrolyzed and the beta sliding clamp ring closes.
Miscellaneous:
MISCELLANEOUS: [Isoform tau]: Produced by full-length translation of the dnaX gene. This isoform is essential, constructs that express only the gamma isoform are not viable; MISCELLANEOUS: [Isoform gamma]: Formed by programmed ribosomal frameshifting to a premature stop codon in the -1 frame at codon 430, the last residue is thus Glu and not Ser. Mutants which remove the frameshift are viable, suggesting strongly that gamma is not essential for viability.
Sequence:
MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERLASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPELAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNRGAQQKLAEALSMLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQTLRRFFDAELDEESIRPI
The following text describes a protein:
Function:
Involved in cell envelope biogenesis. May act as a membrane fusion protein, connecting MmpL transporters with periplasmic proteins, and play a role in cell envelope lipid changes during biofilm maturation; Is also a virulence factor required for intracellular survival. Associates with CBL, a host ubiquitin ligase, and probably blocks the normal functions of CBL and disturbs CBL-mediated antibacterial activity. Interaction counteracts antibacterial defense but causes a reciprocal enhancement of antiviral defense.
Subcellular Localization:
Cell membrane; Lipid-anchor. Secreted.
Sequence:
MKHFTAAVATVALSLALAGCSFNIKTDSAPTTSPTTTSPTTSTTTTSATTSAQAAGPNYTIADYIRDNHIQETPVHHGDPGSPTIDLPVPDDWRLLPESSRAPYGGIVYTQPADPNDPPTIVAILSKLTGDIDPAKVLQFAPGELKNLPGFQGSGDGSAATLGGFSAWQLGGSYSKNGKLRTVAQKTVVIPSQGAVFVLQLNADALDDETMTLMDAANVIDEQTTITP
The following text describes a protein:
Function:
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Plastid, chloroplast thylakoid membrane.
Sequence:
MGSVQLSGSGLVASLPPNHSFSHKTKLNKPNSYFFRSKHNAARTKTVRAISTAPASQPPAADEPDEPPAVDFAFVHSVLLPDGTPDVHWRRANGGQKLRDIMLDSNIELYGPYSKPLSNCAGVGTCATCMVEIVNGKELLNPRTDIEKEKLKRKPKNWRLACQTNVGNPDSTGLVVIQQLPEWKAHEWNIPKNIPNDDDLETST
The following text describes a protein:
Function:
Required for a novel path of interorganelle communication between mitochondria, peroxisomes and the nucleus, thereby maintaining a functional metabolic interaction between the tricarboxylic acid and glyoxylate cycles. In particular, required for the retrograde expression of the peroxisomal isoform of citrate synthase, CIT2.
Miscellaneous:
MISCELLANEOUS: Present with 3260 molecules/cell in log phase SD medium.
Sequence:
MSTLSDSDTETEVVSRNLCGIVDIGSNGIRFSISSKAAHHARIMPCVFKDRVGLSLYEVQYNTHTNAKCPIPRDIIKEVCSAMKRFKLICDDFGVPETSVRVIATEATRDAINADEFVNAVYGSTGWKVEILGQEDETRVGIYGVVSSFNTVRGLYLDVAGGSTQLSWVISSHGEVKQSSKPVSLPYGAGTLLRRMRTDDNRALFYEIKEAYKDAIEKIGIPQEMIDDAKKEGGFDLWTRGGGLRGMGHLLLYQSEGYPIQTIINGYACTYEEFSSMSDYLFLKQKIPGSSKEHKIFKVSDRRALQLPAVGLFMSAVFEAIPQIKAVHFSEGGVREGSLYSLLPKEIRAQDPLLIASRPYAPLLTEKYLYLLRTSIPQEDIPEIVNERIAPALCNLAFVHASYPKELQPTAALHVATRGIIAGCHGLSHRARALIGIALCSRWGGNIPESEEKYSQELEQVVLREGDKAEALRIVWWTKYIGTIMYVICGVHPGGNIRDNVFDFHVSKRSEVETSLKELIIDDANTTKVKEESTRKNRGYEVVVRISKDDLKTSASVRSRIITLQKKVRKLSRGSVERVKIGVQFYEE
The following text describes a protein:
Function:
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
PPPPHPPPQLPKSPLFSGDDNLCNIPQSLPCSPPKQSKKENGPPLPFTPKGRRLVFEDQLASRSPGQRDRAAAPSPGQVRARQGQETPRNSERGHPSEREDVRVGLFKQEGTCYQQAKLALNTAVPDRLPAREKEMEAIGHFLKKHVCGKRAGSLYVSGAPGTGKTACLTRILQDLKGELSGTKVIVLNCMSLRSSQAVFPAIARELFQEGASKPAGRDVVRKLEKQMTAAEAGHMILLVLDEMDQLDSKGQDVLYTLFEWPWLSGSRLVLIGIANALDLTDRILPRLQARANCRPQLLNFPPYTKDQLTAILQERLGQVPGDQVLDNAAVQFCARKVSAVSGDARKALDVCRRAVEIVEKDVRSQTLLRPLSEPSPGPLVPKRVSLCDVSQVIADIYGDRMAASQTGGADPFPLQQKILVCSLLLLTRQLKVKEVTLGKLYEAYSKVCRKQRVPATDQSECLCLSGLLEARGIFALKKNKETRLAKVSLKIEEKDVERALQDRVLIGNILASGLP
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MSADRIQRMRREKGFAWIGSAKSNGKAKRRCNKHYEGFHLPGIGVIKVGDHVLIEGESDESFVALIEDLFDNGQEDTDDPRRAKVQWYMRPSELPKTIARLPSAPLSREIYKYNQSKGASTDVEIDAETIIGKCVVETVEVDSDPPDEKENQGIPVLYARYGINVTTVTPLIEPESEEEEEEEEEEEEEEEDEEEEEEDSEEEEEEVKKVVKKSSQKVNLKPVNKGLTPRRNQTFTADEVWDMFSSDDDMSPWKQTKKSHSKKPAVSTKKESWKVGSVSRSGGRINLIGIKPKVLEGLEMEEKMTRGGRLIKPTPKMSVAKETKAQSKSTSKKQLPTTPIQKSKVVKTPKTVGGRVGRPSKVESLRKTQSCLKESVKQKNNASTPRRRKLTYYEEEEDEDEEEDEEENFKTLKKRKMSASLKSTPQIIGKKRNFSKKDATPGIHSRSTPCKTPSQPLEHARVRLHVSAVPDSLPCRDQEFADIFSFVKSKLLDGTGGCMYISGVPGTGKTATVMEVLHWLKQDAESKDIPKFKCVEVNGMRLTNPHQAYVHIIKSLTGKKATPEHAATLLDKLFSANKATKMPTVLIVDELDLLWTRKQGVLYSIFDWPTRPNAQLIVVAIANTMDLPERIMMNRVVSRMGLTRMTFQPYTYKQLQEIVESRLKGIDAFNSDAVQLAARKVAAISGDARRALDICRRATEIAEVHARKSKKKAVVGMAQVDAAVTEMFCSPKIVAMRQASEQEQIFLRAVISEFRQSGLEEATFAEVLQQHISLCRIEGQLPPTVSDVWGVCKRLASTRLLLLEASTNELGQRVRLNVSQDDVRYALDSRTK
The following text describes a protein:
Function:
Involved in the synthesis of the bacterial cell wall. Catalyzes the addition of alanine into the interchain peptide bridge of peptidoglycan precursor using aminoacyl-tRNA(Ala) as amino acid donor. This alanine is added to the epsilon-amino group of the L-lysine of the peptidoglycan UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine, in a ribosome-independent mechanism. Specific for UDP-N-acetyl-muramoyl-pentapeptide. Has no activity toward UDP-N-acetyl-muramoyl-tetrapeptide or UDP-N-acetyl-muramoyl-tripeptide. Also acts on L-seryl-tRNA(Ser).
Sequence:
MPVLNLNDPQAVERYEEFMRQSPYGQVTQDLGWAKVKNNWEPVDVYLEDDQGAIIAAMSMLLGDTPTDKKFAYASKGPVMDVTDVDLLDRLVDEAVKALDGRAYVLRFDPEVAYSDEFNTTLQDHGYVTRNRNVADAGMHATIQPRLNMVLDLTKFPDAKTTLDLYPSKTKSKIKRPFRDGVEVHSGNSATELDEFFKTYTTMAERHGITHRPIEYFQRMQAAFDADTMRIFVAEREGKLLSTGIALKYGRKIWYMYAGSMDGNTYYAPYAVQSEMIQWALDTNTDLYDLGGIESESTDDSLYVFKHVFVKDAPREYIGEIDKVLDPEVYAELVKD
The following text describes a protein:
Function:
Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MFRITNIEFLPEYQQKESREFLSVARTVQQVINLVYTTSAFSKFYEQSVVADVSNNKGGLLVHFWIVFVMPRAKGHIFCEDCVAAILKDSIQTSIINRTSVGSLQGLAVDMDSVVLNDKGCSQYFYAERLSLHYPLEISATSGRLMCHFKLVAIVGYLIRLSIKSIQIEADNCVTDSLTIYDSLLPIRSSILYRICEPTRILMSFVSTNNLMLVTFKAPHIRRLSGIRAYFEVIPEQKCENTVLVKEITGFEGKISSPYYPSYYPPKCKCTWKFQTSLSTLGIALKFYNYSITKKSMKGCEHGWWEINEHMYCGSYMDHQTIFRVPSPLVHIQLQCSSRLSDKPLLVEYGSYNISQPCPVGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVSSQPACNTSSFRQHGPLICDGFRDCENGRDEQNCTQSIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEEGCTCSRSSSTLHRIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHFGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPAGQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTYGIITSRMLCAGVMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGCGRPNFPGVYTRVSNFVPWIHKYVPSLL
The following text describes a protein:
Function:
Component of the exocyst complex.
Sequence:
MLGSEESCGASNCSINNGHDDRDMDRLLRQLDVGWVLHAADADSDAGSSRQLRHRTATWLRALAEILHTYSYFRNNGATPAPAGNFFCVMHRRYWEEVSGTPDQQNFTRFAGAAISKMLPFVDSLVAPAPPRTATVDDGALPAQRLQALIQVRGALTRIRGIAELRPATSAEVASVHDELFSLLSAKLARLDEAVWNTMEEVRACVMSSTEEDDDGGGGGSDSDSWGNHSVLHGSSHIHRMTRSVLNYTNLLQTDYGSLHRIVYEAAKLRKCAPAIGSIGRYSSLPKFESEFHKVYSTQKLWKVPDPELRTRLRKAVIEKVNPSFTEYLQDSTVITEGITLTPQELEEMLQELFEG
The following text describes a protein:
Function:
This promotes the activity of RNA polymerase II.
Subcellular Localization:
Nucleus.
Sequence:
MADSDSAQPTSSSENDSEFAALLEAELDKDDWGSEDQNAAGVDSHSHERVDIEDVDNQIGAQVAEAPLIGHAASQAVDEPGGAEGKGKEAGICPPHPGYMWNICIRCGKAKEEDDDEKGVALRYLHQGLEVSAVEADRLRKDDLQKLLAQKKLYLVVDLDHTLLNSTRMAEVPDSDAAYLRSAYSPTTVFPPAAAPSANEDDLLYQLPPLSMWTKLRPFVREFLEEAAGLFEMYVYTMGEKLYAQAMARLLDPSGRLFGERVISQQDSTSRKTKDLDVFAVLIFDDTEAVWPKNRANLLVIERYHFFRSSRRQFGLPGESLVEAKKDECSEEGALRGILDTLKTVHADFFAPRTAPADVRQVLASVRRGILSGCHVVFSRIFPQGFPHHESHPLWIRATELGATCSLNVTLETTHVVAVEPGTEKARWARAEGKFVVRPEWLDCCQLTWSHAREEDFPVLPDWRTRGAAPEFARTVDRKEPEPETSSADGTDESDEDVEVTDGERAGPSEAATSGGSGDEKRERTDDEREEGDAKQSGDARGEDRQQAVENGLASVARSVGNEESREGATESTQRTEHASKRQKQEHEVDEGTL
The following text describes a protein:
Function:
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Sequence:
MTQIVGIVNITTDSFSDGGQFLDAERAIGHARRLRGEGAHWIDLGAESSNPDGEQVTAEIEAERLAPVVAALSADGVSVAVDTCKSSVMVRCLELGARMINDITALADPRSVEVLKTFRVPVVLMFARNRQARAEQRPGDCETVWNEIEAFFSGRIDRLLGAGLQERQLILDPGMGFFLGSNPEPSLRVLAHVDRLGRFGLPVYLSVSRKSFIGSVLGGRPAGGRDHGTLAAEIWAYLAGVDYLRTHAVAPLSDAIRVIAAIRAQALA
The following text describes a protein:
Function:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.
Subcellular Localization:
Chromosome. Cytoplasm.
Sequence:
MMPQVLPKRRSEKSDERRISTSSSTNSSNNHNHTPNRATPTSNRIMANRKVSNRIMSARHVSRSIAEDADTSNSFDDGIGFNENKHTIMSNFEEWIKMATDNKITVKNSWNFDLIDYFHDLNVIKDGESINFQRASATLDGCVKIYSNRVESAATETGKLLSGLSKKDDGHHGNQEAGNGDDDENGENGDDDRDGNDEDSRKKRKFNRIVESTLVEFDAIKVKKLEQELAIDPLFKKALAEFDEGGAKSLLLNTLNIDVSGRVVFDATSNPIQETEDANQIETDSQQVQELQTSDTKQSAISSLKSFLFKDNENFDDLTLCPSLVEFQSALADVNKAKSILNDFNSKITNAAQEPLAFKESEENNDFDLGDFNDFGGNDDFNDDINTHDNSSHNDPYNNIDNTIMKALFNDKTDSSIYSRTQSTAIMDQDLMAYFDDRMKSNWRGPDNWKVAAFKKANNIDQKQSDSSVKQESSAQTSTARRKPENIIIDFFNDDDDVDEDILFEPPKSLNSISKKGNFKSSDYILPDDIKYNSARLTNLFTKPQIAIMYYGNKRLQGIDGQLLTDQNYFAEQYRQHEEEERDRLANSFHQAECEDFDNDFGDNNDFGGVDFNDALEADVPEVATSETQSVMGKRRPEYVNFSRVAKRVDVKLLKDNLWVVMKNQLADQKEDSPDKEEEEEVAEKQTTIDFKSVVQNVLRTYRPEQAKDLSTSFCFICVLHLANEHGLAIQSNEAHNNLTIIGS
The following text describes a protein:
Function:
May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAPKGKVGTRGKKQIFEENKETLKFYLRIILGANAIYCLVTLAFFYSSASFWAWMALAFSLAVYGASYHSMSSMARASFSEDGSLVDGGMDLNMEQGMAEHLKDVILLTAIVQVLSCLSLYIWSFWLLAPGRALYLLWVNVLGPWFAADSGAPAPELNEKRQRRQERRQMKRTQVPAPCFHSPA
The following text describes a protein:
Function:
May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDKLKKVLSGQDTEDRSGLSEVVEASSLSWSTRIKGFIACFAIGILCSLLGTVLLWVPRKGLHLFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIATIMVLLCFALTLCSAFWWHNKGLALIFCILQSLALTWYSLSFIPFARDAVKKCFAVCLA
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MSIRSAFIRPVVSFTKKGASNASSSRGGGIPLLAMMSTYSKQSTDVAYRLATPLKARSLAAQLFIRGGTSAMRSPINHAHRSNTLRATSSSTNSSGGQKDKASSEKTTGTEGEEPMSQEIVLTPGEKVVVGTRLFFWAGAFAFASVCAYYIGKELIPTKMSPNNVFDKATSIIRENAEVKRRFGEAFKTYGRDHGGHREGRRNFIEHTEYVSPDDGTKRTRVRFNLEGQYGNAFVFAEVSKDMPSGEFVYLLVQDKRNGQVITVVDNRSALLAKRMAGGSQEGADVFANLLGGGKK