lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the intracellular transport of cholesterol. Binds cholesterol or other sterols.
Sequence:
MEGLSDVASFATKLKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVIDDLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFSYTVGYKEGLLSCGISLDWDEKRPEFVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGMIPQSAVDTAMASTLTNFYGDLRKAL
The following text describes a protein:
Function:
Has holdase chaperone activity that may fold catalase to a functional structure. Not required for the peroxisome import of catalases. Required for the activity of catalases and acts mainly at the post-transcriptional level.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
The RING-type zinc finger domain (1-158) is involved in the increase of catalase activity and zinc ion binding is required for this increase; The interaction with CAT2 is through the C-terminal TPR-containing domain (159-405).
Sequence:
MTTTSVCPFSKAARPDDGSTRKQGEITASGCPFSKAARPDDASARKQGETTASGCPFSKSARPDENGSKGCPEQEGNLNKDSTDSATVPAKCPFGYDSQTFKLGPFSCMLCQALLYESSRCVPCTHVFCKVCLTRFKDCPLCGADIESIEVDENLQKMVDQFIEGHARIKRSVVNGTEKEEVENDNKKVIYADVSMERGSFLVQQAMRAFSAQNYESAKSRLAMCTEDIRDQLGREGNTPELCSQLGAVLGMLGDCSRAMGDSSSAVKHFEESVEFLMKLPLNDLEITHTLSVSLNKIGDLKYYDEDLQAARSYYDRALNVRRDAMKHHPNAPSQILDVAVSLAKVADIDRTLQNEVAATDGFKEGMRLLESLKLDSEDSALEQRRLSVLEFLKKQVETDAETAL
The following text describes a protein:
Function:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. Interacts with CLEC10A at antigen presenting cell-T cell contact; CLEC10A on immature dendritic cells recognizes Tn antigen-carrying PTPRC/CD45 receptor on effector T cells and modulates T cell activation threshold to limit autoreactivity.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Membrane raft. Synapse.
Sequence:
MPGGGVGGALSSDPLTPASLSVCSWGGLHPRGGVPGSSGAAGSRATCFPPGRGSYGGGGVLGAGRQRHPTVARSTCTHHPTQLLSAPREAHPWVHRAGCASPSATLHPGLHTRSSAAGLGCQPPTRSPGCIPTATQGHPPPRGGFSGWGPRTGSARPDGTCRVRPGSHAPCRCPRGSTEQGPPGAGPRGPGSAGGPVWPSPCVGDTTPAATAFVLAGSSGEWTTPRTFPADPAATPVASPPPARSSSAAPPRASSIPANASSSDETHTSTSPATSTNHTTAPTTIVSPEPRQTCEDRYANITVEYYYEPNSFVAKLNVNDTVNCDQCKKNEISNLKECENLNITISHSSCDSPNKTLTLEVPPDRGNFDLEDCTQKEKANTSICVRVEEKKNFTCDKSKIKYRLQCDNRTPSKDMQFEWEGFVPETDYSCYLNVSYNGQLVLNLSKIIETDFGSPDPPKNLICSSKNANSVVIIWEPPINTFHGYNVCYHINEEIQSHASGQEEAYFHQEMCQELGETVKQHQLQQLNPYTKYRVSVKAYTNGKVRREGSCEVCDVKTNESNPGPVRDLHFSRKSDNSVQVRCKPPAAYNGPKNGNYHLQIRIGDVLVNDLLNKACEFLVENLHYSTEYKFKVYYNNGKFDGASQNFSHTTSYNSRALIIFLVFLIIVTFLALLVVLYKIYDLRNKRSSDLDEEQELVERDDEKQLMTVEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFSIKDARKPFNQNKNRYVDILPYDYNRVELSDINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVIVKITEHKRCPDYIIQKLNITNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVSLSELHPYLLNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQHVGNQEQNKSKNRNSYIIPYDFNRVPLKHELEMSKESEHDSDESSDDDSDSEETSRYINASFVMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTQLKDGDQEACAQYWGEGKQTYGDVQVDMKETNKSSAYTLRVFELRHSKRKDSRTVYQYQYNNWNVDELPAEPKELISMIQALKEKSPKNSTEGNKHHKNVPLLIHCRDGSQQTGLFCALLNLLESAETEEVIDVFQVVKSLRRARPGMVPTFEQYQFLYDVIANTYPAQNGQIKKSNNQDDKVEFANELVDKAKQDANCVSSPGAPDKTNEGNKEDEGTKVTSSPEEPEHSANGPASPGLTQNA
The following text describes a protein:
Function:
Has a broad aminopeptidase activity on non-blocked peptides by progressively cleaving amino acids off the peptide substrate. Aminopeptidase activity stops at the residue before the first proline in the peptide. Cannot cleave when proline is the first N-terminal residue.
Sequence:
MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGSVLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRITTREECKIPGLLDGDRQGNDVSAMRVDIGARSYDEVMQAGIRPGDRVTFDTTFQVLPHQRVMGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAIVLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWVETVAAEIGVPLQADMFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMQQLLSALIQRLTRETVVQLTDFR
The following text describes a protein:
Function:
Confers a modal distribution of chain length on the O-antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVIYGQAAPKVSDLQETLIGRFSSAFSALAETLDNQEEREKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKLAQYIQQVDDKVNQELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQIQQTGEDITQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDIESLKVDDLDIHAYRYVMKPMLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNYNAK
The following text describes a protein:
Function:
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMVSSEGSTESEHLDGMEPGQKVHEKRLSNGSIDSTDDTSQIVELQELLEKQNYEMAQMKDRLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIRECYLQAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQMKMRTGSLIEPTISRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNEARSSLSASLEPDRLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC
The following text describes a protein:
Function:
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Subcellular Localization:
Secreted. Cytoplasm.
Sequence:
MMKSVFFGVVAITVAILSIYQETAQAQEQTVGATDNYQWDSVDDQCLAALHRQINKEFDASIIYLKYAAYFAQEKINLPGFEKFFFHSAAEEREHGIKLIEYALMRGKAPVDKHFKLNYDHEVPTVTTGESALETALQKEVEVTKSIRGVIKACEDGSNDFHLADYLTGEYLDEQHKGQRELAEKIATLKKMKKSAPKLGEFLFDKNHM
The following text describes a protein:
Function:
Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MNARLLLLLAASASSAAATATCPVYVQSQTTSTLTDPITKIVSSSSSGSGSGGSATSSSSASGSNFSDAGSQAGTNNADVGSLSSGSGTSAGSSGASTSTTTAGSADSTGSAGVSTTPTTTTTPSSTTKTPSSTTATPTSTTATSTTTGSASATATTTTTTGPTTTAPSADTTTTATTTTSSGSTGTSAGTTTSLSLGARKLQTTTTGSTTGTTGTTTTAGSTTAGTTTTTTTTAGSSSTSGTVGSGSSSSDVLTCDSTFYSAWDTLGLTCGGASIDVASAVSASSCVIYSGSVGSTSGSTCVSICSFPACTNSAWVYGGDNGISSSVYDGLSLESFLSSDVIAALEQRSSTVSTFLSNSTMSDSQQCTYSSESSFSSCSCSAMLIDSSASGSVADAAKKQQREQDEVDGVITKDNTTTTGTVVAATSKSVAGVTVAITGIAAIASTAVGGVSSAGASLAAAGSTMAITTVEICQFGVLVNQLQLDGKSSALAQFGKAMAPAAFTFLPFGKLEDGSDSSSSGSGSTSSSSSNAGRRLASSSSSGSSSSSSTDQLTGIAKYSRQLNIEEDMLFIVTLAGVFCVMACVVGLFGIGYLVSGLMMPREEYLSKFFDKMIGLEVLVAILSQYTIGVTATFQIYYSMKYESITDPKCLLAIAAIVFLAAGILVYGYIVIKKHEAEIADVGTVQHMKKTVNMRYGPLYEEYKYKNRYFFAAKMMLALTTGVVTGCASMSGTVQVSIILALNVLFFFYLEIQSPHHSKFVQTTTSFVSIMKIAVLVLTFFLVTAAASDGFPTSLQNGISVAIVGLNLFVLALLMIRSLYTFWQKFKLQRDAAYDQEEQTAQDYFKDETPAGRKASNAQQPTGQPILQSQYSNVNNTSTNDNPYVQGSNAVDYNSADEIRLRSATHEDDDRQQTYDASRRSAANHYITQDRNTCKRECFMQDDMVEKAGESIQGWLGTVAFVVMVSGDYKGSEEMASGSLLTQGLESLGSKSKAIGSKLDELYALDDELQAAHQQAKRDDDFGEEVVTKYKNFLTCRQQLIAELEKQKISVPWQLRMTIDDLELTLKQRREKKEGKTNTKGEQKKKEVSPSKLNTEPESVQTAQSGRVAVAFLGPTLVALVIAMLCSTKLLRARVLPRNHLAMASTTSCDCGHVIGDLTSLGPLQRGARVLVVGDGNFSYSRAFLRANSVRIGASELLVTATSLDTESQLLEMYPKSREILDELRSGGVNVRHSINATKLESYTFGAAFDRVVFNFPHFAADGGVGNRNKRNKIHRHRQLLVDFFASASQMLASHGQVWVTLCAGQGGTRLERKTRAVGDTWQIVHCAAAAGLVLQDAHFCPVDALAALGYYSVGYQSREKAFWTEDGISHVFSHEAPGRKSIFPIEWARDVSFWVTDEQLFTEELLYAVVREHFPPENMDVSISLLDEYRCEKTGRKSVTYRLDISSWSLALSRDRVNALAQAALTAIESSRFGASRAT
The following text describes a protein:
Function:
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Subcellular Localization:
Nucleus.
Sequence:
MIVPDGMLNDNQKGIVVGKLRNPKTGTGTLYAFSHNNTKLYEMNQFDENKRSWFIDNSVQSDGSFFLTTTIDPLFVIIPYLQKAKHTSPIDQLLVDEEYTDTGKLSLCSKKDDLEKIADCKQSGTFQAWKYNEGKTFDWLGKKVSRLTQHLKDKNFNVTQSAVSSNYVKTDSATVPESSFTRYAFGLISEYLSDELSAALEKHLDLPAVPKFANNEDVKEPPAKRQKFGSDIKSEPTEDYSKDQKPFVKVSQSRYTFSAKSKALASAAKGSKSIASFFGKK
The following text describes a protein:
Function:
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
Sequence:
MASMACASLHCAMAPLSVASSSYVVRTQSARIFVSRIQPGVWEKAGAKRLRASSQENATVVKNRSIYTSASSARENATVVVTREQGKNGKLMNALSARGINCLELPLIEHKEGADYPKLAQTLRETEFEWIVITSPEAATVFLSGWRAAACPKVRISVVGSGTGEVFEEMKDNLDKLEVAFTPSKATAKVLAVELPKLEGGNGAILYPSSAKAGSDLETGLIARGFKVLRLNTYSTESVKSLDQDKVAAALAAPVATFASPTAVRAWVELLGPWNGAAACIGTTSAKAAKTAGLSKVFCPDSPGIDGWVESVMEALESHALDRSLT
The following text describes a protein:
Function:
Catalyzes the concluding reaction of the photorespiratory C2 cycle, an indispensable ancillary metabolic pathway to the photosynthetic C3 cycle that enables land plants to grow in an oxygen-containing atmosphere; [Isoform 3]: Cytoplasmic D-glycerate 3-kinase that constitutes a photorespiratory bypass that alleviates fluctuating light-induced photoinhibition.
Miscellaneous:
MISCELLANEOUS: [Isoform 1]: Expressed in the light; MISCELLANEOUS: [Isoform 3]: Expressed in the dark.
Subcellular Localization:
[Isoform 1]: Plastid, chloroplast. Note=Expressed in the light; [Isoform 3]: Cytoplasm. Note=Expressed in the dark.
Sequence:
MAVAISGSSLISSTLQHYNNRIYIRDYPIPCHSSNPICNSFNFKRRSFSPSSPKFNDHVVNPSSSYLSSKLSPIRTHSSFAACGCSWIQDNSMVHDYATTTNGTSKRCSALPTTNTVDVSSVSDLFEFICSGPLVNKIGITPQRVGQSIDKWLLYGSQLCRLFQLNELKLTIPQKARLYHYYIPVFIWCEDQIALHNSKFKDGDDVPPLVIGFSAPQGCGKTTLVFALDYLFKTTKKKSATISVDDFYLTAEGQAELRKKNPGNALLEYRGNAGSHDLKLSVETLEALSKLTKEGLKMKVPRYNKSAYSGRGDRADSSTWPEVEGPLSVILFEGWMLGFKPLPADVVKAVDPQLEVVNKNLEAYYDAWDKYIDAWVVIKIQDPSYVYRWRLQAEIAMRQDGQAGMSDEEVNDFVSRYLPAYKAYLPTLYAEGPSGSDPDRVLAIDIDEERNPILAN
The following text describes a protein:
Function:
Required for sterol biosynthesis. Functions as a positive regulator of cytochrome P450 enzymes erg5 and erg11. Function requires bound heme.
Subcellular Localization:
Endoplasmic reticulum. Membrane; Single-pass membrane protein.
Domain:
The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 77 and 101.
Sequence:
MASTQVVFIVTLFLYLLITRWRRKNEKSFIASEEPKQPEWRDYTPAELKEYNGSKNSLVFLAIKGTVYNVTMGSKFYGPQGPYSAFAGHDASRGLAKNSFDDEFIPDSDAEELDDCSDLNDEERQALNDWKAFFDQKYQAVGRLISPREARAAATISETEEKVAHN
The following text describes a protein:
Function:
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
Sequence:
MSLRVVYLGTPQFAATVLKTLLDAHTHIVGVVTRADKPQKRSSKLISSPVKQLALSKNIPLLQPIKTTDPAFLAQLREWQADVFIVVAYGVILKQELLDIPTYGCYNLHAGLLPAYRGAAPIQRCIMDGGVLSGNTVIRMDAGMDTGDIANVNYVAIGEDMTAGGLAEALAASGGELLLKTLQEIEAGTVRHVPQNEAMATLAPKLTKEEGGIHWDAPASQVYAHIRGVSPAPGAWTRYLSQGKEARRLGVLSARMESFSGNYGDPGEVLGVSGEDLLIACRQGALRLRMVQPEGKALMKAKDFFNGQSRLVSKLF
The following text describes a protein:
Function:
RNA-binding protein that associates with the RNA exosome complex. Involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and plays a role in recruiting the RNA exosome complex to pre-rRNA; this function may include C1D.
Subcellular Localization:
Nucleus, nucleolus. Cytoplasm. Note=Cytoplasmic in M phase.
Sequence:
MASERKTKLSKNLLRMKFMQRGLDSETKKQLEEEERKMISDEHWYLDLPELKEKESFIVEEQSFSLCEDLLYGRMSFRGFNPEVEKLMLQMNSKNRAEAAEEDETVEVDVSDEEMARRYETLVGTIGKKFVKKRDRANYEEDENGTIKAIKPKKMFLKPQD
The following text describes a protein:
Function:
Stimulates oocyte maturation by promoting meiotic G2/M progression in resting oocytes, via activation of the MAPK cascade and cdc2-cyclin B. Also activates the kinase activity of cdk2; this activation does not appear necessary for oocyte maturation. Necessary for polyadenylation in oocytes.
Subcellular Localization:
Nucleus.
Domain:
The C-terminus is required for CDK2-activation, but not CDK2-binding.
Sequence:
MRHMQSATRATLVCGSGVKQIIAKGHPNTRVFGARKARIPEREVLAAKPKITRITHLNLQPQERQAFYRLLENELIQEFLSMDSCLKISDKYLIAMVLAYFKRAGLYTGEYTTMNFFVALYLANDMEEDEEDYKYEIFPWALGDSWREFFPQFLRLRDNFWAKMNYRAVVSRRCCDEVMAKDPTHWAWLRDRPIHHSGALRGYLRNEDDFFPRGPGLTPASCALCHKASVCDSGGVAHDNSSPEQEIFHYTNREWSQELLILPPELLLDPESTYDIHIFQEPLVGLEPDGAALEWHHL
The following text describes a protein:
Function:
Responsible for conferring a stable 5'-end on cytochrome b mRNA.
Miscellaneous:
MISCELLANEOUS: Present with 2180 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MFLPRLVRYRTERFIKMVPTRTLRRINHSSRDPIQKQVLALIKANANLNDNDKLKIRKYWSDMADYKSLRKQENSLLESSILHEVKIEDFISFINRTKTSSMTTRGIYRRECLYQCKKNLDLVNQVVSQVSSVRHQKPLTTQLDTMRWCVDDAIGTGDIVMAADLFLLYYRLFTDDKKLDEQYAKKIISVLAYPNPLHDHVHLVKYLQLNSLFESITGGGIKLTRFQLETLSNKALGLSNEAPQLCKAILNKLMNINYSLTNDLKLRDDQVLLAYKSIDENYRRGNVASVYSIWNKIKEHYVSISAHDSRIIYKVFKICTHNRAYRSICSEMFWQLTPEYYCNNPLILPAIIDFITKQDSLTMAKELMQNINRYTLPENHHIVWLNKRCLSSLLRMHLKFNDSNGVDRVLKQITTNFRALSQENYQAIIIHLFKTQNLDHIAKAVKLLDTIPPGQAMLAYGSIINEVVDWKLASKVKFTDNLMALVNDLLTKAHDFDPDHRNSLWNVVSALYIKKLCHYKKRDGKFVANAKKDIDLAKLLYINAAKRSKTYWTKSNCNPFIASSPCDVKLKVNNQNRFTILRNIALSALQIGRTDIFLWACAELYQNGMTIEELKLDWNFILKHQIRNSEFKTNKEIIQDIKKHGVSAVKRYLR
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MAEVLEKVTKIIVDRLGVEESKVTLEASFKEDLGADSLDVVELVMELEDEFGVEISDGDAENINTVGDAVKYIEANA
The following text describes a protein:
Function:
Reversible hydration of carbon dioxide.
Sequence:
MEETGMVSSVFFYGSLMVLLVCNIVVANGEDFPFGYANGTQDPSEWGHLHEEWKACLGYGHHQSPIQLNYTKQEIQKQFIPLNRAYNMSRITMINRYHDIMMRFENPYVGGFVHSGTNFYLRQLHWHKPSEHEINGEKFHVEMHMVHTSHDHKESAVIAFLYKLGSPDPFLAEVEKYIRNISGAEGQKIDAGMINPNDTIEQYHGYYRYLGSLTTPPCTEGVVWTVMQQVRSVSMEQVQMLINATPDFKDNARPIQNIDNRNIKVYQP
The following text describes a protein:
Function:
Catalyzes the reduction of NADP in the presence of molecular H2 to yield NADPH.
Sequence:
MAATTTEKKQLRIATRNCGFIDPESIDDYIALRGYEGLAKVLTMTPAEVVDLVKRSGLRGRGGAGFPTGIKWGIALGNKADQKYMVCNADEGDPEFMDRAVLEGDPHSVVEAMAIGGYAIGATRGTVYIRAEYPLAIKRLKKAIDDAREYGLLGENIFGSGFDFDIELKYGAGAFVCGEETALIRSMEGKRGEPVTKPPFPAQSGYWEKPTIVNNVETFANIPAIIINGADWFSGIGTATSKGTKVFALAGKIQNVGLIEVPMGISLREVIFDIGGGCPDGKAFKAVQTGGPSGGALANKDLDVAIDYESLAACKSIMGSGGMVVMDEDDCMVSVAKFFLDFTMDETCGKCTPCRIGSKRLYEILDRITKGKGTRADLDRLKSLSEIIKDTALCGLGQTMPNPILSTMDTFANEYEAHVDDKKCPAHVCTALLTYTIDPAKCTGCGLCTRVCPVECISGTKKQPHTIDTTRCIKCGACYDKCKFDSIIKQ
The following text describes a protein:
Function:
Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Sequence:
MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSRNVREEKTRSEINFGQVKFDPPLRKETEPHHELPDSDGFLDSSEEIYYTARSNLDLQLEYGQGHQGSYFLGANKSLLKSVEEELHQRGHVAHLEDDEGDDDESKHSTLKAKVPPPLPPKPKSIFIPQEMHSTEDENQGTIKRCPMSGSPAKPSQVPPRPPPPRLPPHKPVALGNGMSSFQLNGDRDGSLCQQQNEHRGTNLSRKEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFSVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIDFPIPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDTPQTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDSTRIFRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY
The following text describes a protein:
Function:
Required for resistance to DNA-damaging agents.
Subcellular Localization:
Cytoplasm.
Sequence:
MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSVMHEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCHKHHFDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD
The following text describes a protein:
Function:
[Protein SLFN14]: Shows no ribosome-associated and endoribonuclease activities; [C-terminally truncated SLFN14 endoribonuclease]: Displays polysome-associated endoribonuclease activity towards mRNAs and rRNAs. May play a role in RNA surveillance pathways by recognizing stalled ribosomes and triggering endonucleolytic cleavage of aberrant mRNAs (Probable). Cleaves different types of rRNAs and mRNAs in a magnesium- and manganese-dependent and ATP-independent manner (By similarity). Involved in correct maturation of megakaryocytes and especially important for proplatelet extension.
Subcellular Localization:
[Protein SLFN14]: Nucleus.
Sequence:
MESLKTDTEMPYPEVIVDVGRVIFGEENRKKMTNSCLKRSENSRIIRAICALLNSGGGVIKAEIDDKTYSYQCHGLGQDLETSFQKLLPSGSQKYLDYMQQGHNLLIFVKSWSPDVFSLPLRICSLRSNLYRRDVTSAINLSASSALELLREKGFRAQRGRPRVKKLHPQQVLNRCIQEEEDMRILASEFFKKDKLMYKEKLNFTESTHVEFKRFTTKKVIPRIKEMLPHYVSAFANTQGGYVLIGVDDKSKEVVGCKWEKVNPDLLKKEIENCIEKLPTFHFCCEKPKVNFTTKILNVYQKDVLDGYVCVIQVEPFCCVVFAEAPDSWIMKDNSVTRLTAEQWVVMMLDTQSAPPSLVTDYNSCLISSASSARKSPGYPIKVHKFKEALQRHLFPVTQEEVQFKPESLCKKLFSDHKELEGLMKTLIHPCSQGIVIFSRSWAGDVGFRKEQNVLCDALLIAVNSPVVLYTILIDPNWPGGLEYARNTAHQLKQKLQTVGGYTGKVCIIPRLIHLSSTQSRPGEIPLRYPRSYRLADEEEMEDLLQALVVVSLSSRSLLSDQMGCEFFNLLIMEQSQLLSESLQKTRELFIYCFPGVRKTALAIKIMEKIKDLFHCKPKEILYVCESDSLKDFVTQQTTCQAVTRKTFMQGEFLKIKHIVMDETENFCSKYGNWYMKAKNITHPKAKGTGSENLHHGILWLFLDPFQIHHADVNGLPPPSAQFPRKTITSGIHCALEIAKVMKEEMKRIKENPPSNMSPDTLALFSETAYEEATCAQALPGVCETKTNLTTEQIANYVARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLALLKAMELIETHRPSEVVFSPATGVWGSHIVLDSIQQFSGLERTVVFGLSPECDQSEEFHKLCFASRAIKHLYLLYEKRAAY
The following text describes a protein:
Function:
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Membrane; Peripheral membrane protein.
Sequence:
MESTLLSVGASTMSIAALSRSLNSHSTPIIAHLHRRFSTTLPSQIALLQLSRRVELRRFGPGHLVRGHDSVDLRRNRLQFSVRSASSGGGGFDGIDGGAGGGGGGGDGAAEGGDAKASAVTSGAAGASPLSSEVIILDVGGMTCGGCAASVKRILESQPQVSSASVNLTTETAIVWPSSEAKVVPNWREDIGEALAKHLTNCGFKSNLRDLRRVNFYENFEKKINEKRELLKKSGRGLIVSWTLCAVCIFGHLSHFVGAKAAWIHALHSTGFHVSLSLFTLLGPGRQLIVDGMKSLLRGAPNMNTLVGLGALSSFAVSSLAALMPKLGWKMFFEEPVMLIAFVLLGRNLEQRAKIRATSDMTGLLSILPSKARLLINGNAEELSSTVEVPSSSLIVGDQIIVLPGDRIPADGIVKAGRSSVDESSFTGEPLPVTKLPGAEVAAGSINLNGKITIEVRRPGGETAIGDIVRMVEDAQTREAPVQRLADKVAGHFTYGVMALSAATFMFWNLFGSRILPAAIHQGSSMSLALQLSCSVLVVACPCALGLATPTAVLVGTSLGATRGLLLRGGSILEKFSTVNTIVFDKTGTLTIGKPTVTKVVIQGGQKYANSELDSNSRHNWSEVEVLQLAAGVESSTIHPIGKAIVNAAKALNCPNVKVTEGTFTEEPGSGAVATVDEKKVAVGTLEWVQRHGVVGDSPFQEAEEFKNQSVVYVGVDGVLAGVVYVEDQIREDAKHVIESLTRQGINTYLLSGDKKSAAEYVASAVGIPRERVSIYMT
The following text describes a protein:
Function:
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix. Zona pellucida. Cell membrane; Single-pass type I membrane protein.
Domain:
The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
Sequence:
MLGELAVGRMRGGCVVLGLLCCLVAGVGSYTPWDLSWTARGDPSAWSWGTEAHSRAVAGSHPVAVQCQEAQLVVTVHRDLFGTGRLINAADLTLGPAACKHSSLNAAHNTVTFAAGLHECGSVVQVTPDALIYRTLINXXXXXXXXXXXIRTNPAVIPIECHYPRRENVSSNAIRPTWSPFNSALSAEERLVFSLRLMSDDWSTERPFTGFQLGDILNIQAEVSTESHVPLRLFVDSCVAALSPDGDSSPHYAIIDFNGCLVDGXXXXXXXXXITPRPREDVLRFRIDVFRFAGDTRNLIYITCHLKVTPADQGPDPQNKACSFNKARNTWVPVEGSRDVCSCCETGNCEPPALSRRLNPMERWHGRRFRRDAGKEVAADVVIGPVLLLADPGAVGQLQEDGDGEAVTVPSVETGLVCVAVAVALAAVGVAVGIARKGCTRTSAAA
The following text describes a protein:
Function:
Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
Subcellular Localization:
Membrane.
Sequence:
EVQRGQGRMEKPTEHPERVNNASSLGPMPRPPLAVQAVTLTLVPLVCTVGVVGNAMVVLVVVRSRHMVTSTNCYLVSLATADLLVLLAAGVPTVAEAASARVWVFGHAGCLGITYLQYVGINASTGSITAFTVERYLAICRPLRAQALCTVARAKRIAASVWLGTGAYCVLWLFLVDTRETAYADGVQVQCGYRPRPAGGDLGRSGSAHQGGPAGPGRSSSRGRRGAFNSQKQVAKMLGVVVVLFALLWLPYRTLVVVNSFLSPPYLNLGFLLFCRLCIYLNSAINPIVYALMSQRFREAFHGLFRCRLAQSKLPPEEATPVYYSVIKDCPQHRLGSWKEPGSLMSRQGGDPGTSGQGPPSYPY
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSRINEIMKIAQPIRDNYFARSPPWSKGGRFRVGTYLPNLDRARLVFSVRDMEPLEQWYVLSGYVRFHQWLGFQPYRLASGRVSPFAVLTLAQFLGVLVNLALIIYRRRCILYHCEAIGMVVDFIKLLTIGLSILVMYVELFRTSDNICGCWRLLYKAHQTLQRYGMVDHRRLTRVMRLYWWFVLGSLLYFVVNESYLYLCAEQMQTKRFYVYFFALQYILNIKLQQIIYPAILLDTYLRMTRAALEHHVGLLQCSERLGSMRYMEFLAGKLNALKALYSDLFQASVALNEAYGRTYLIIYCKNYIHILSNSYWVVFWLLNNQRHHAARIISRLICRIILLGATFYINSCAMKSAQNLRHRLHTMDLGIQIKCQALFTRIESFLQQTQFESIQLTAGDFFDLNFSPILTIIFSVGAYISIFIQQAINQIDELKCNDYEKQC
The following text describes a protein:
Function:
Putative pheromone receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH
The following text describes a protein:
Function:
Probable regulatory subunit of type 2A protein phosphatase involved in the control of the dynamic organization of the cortical cytoskeleton. Plays an important role in the organization of interphase microtubule arrays in part through the regulation of nucleation geometry. Required for the reorganization of cortical arrays in response to light.
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Note=Predominantly cytoplasmic, but at the late G2 phase localizes at the cortical region corresponding to the preprophase band.
Sequence:
MYSGSSDGESHDTSTQRKIPPASSMLWVRNLRRYIGSGAGLGSEALMELETKRILLEIFKEKQQKSQEAGTIPSFYKKKPEEGSISQRVQKLAKYRFLKKQSDLLLNADDLAAMWVCLRENCVIDDATGAEKMNYEDFCHIASVCTEQIGPKCRRFFSPSNFMKFEKDEAGRIAILPFYLYVMRTVSLTQARIDMSELDEDSDGFLHSDEMESYIGGLIPNLAQLRDMPPAFNQMYCRIASQKFFFFCDPHRRGRACIKKILLSNCLQELMELHQESEEEVTDTEQAENWFSLTSAQRICDMFLALDKDMSGSLCKQELKEYADGTLTEIFIERVFDEHVRRGKIVAGNSREMDFDSFLDFVLALENKDTPEGLTYLFRCLDLQGRGFLTTADIHSLFRDVHQKWIEGGNYELCIEDVRDEIWDMVKPSDPLKITLGDLLGCKQGGTVASMLIDVRGFWAHDNRENLLQEEEEPPEEESQ