lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Promotes the exchange of Ras-bound GDP by GTP (By similarity). May regulate signaling pathways downstream of receptor tyrosine kinase, egl-15 and let-23. Required for larval and male spicule development, fluid homeostasis, vulva induction, spermatogenesis, and oogenesis by promoting meiosis prophase exit during oocyte maturation. Required for the delamination of G1 cell by promoting the loss of cell junctions and detachment from the excretory system during larval development. Plays a role in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine. Regulates synaptic levels of nAchR subunit lev-1 in the nerve cord.
Domain:
The DH (DBL-homology) domain may inhibit the Ras-GEF domain, thereby preventing excessive let-60/Ras activation.
Sequence:
MSIMSISLHSASSDTVSLTSRRTISTSKHWAAIFDERIYQICNIVHPGLPIDNAAVEHIRYFLQSIVFELIEARATSVVEVDKTAKKLFAFGLQTVCKEAWDNMHQQLQKHKYQKALKTVLESQHRLAAVIKETLGPREKEKKDREKKEIERIACYIYYACESVTEDVLRLTGNYVKNIRNSEQKITMANLDVAMNGDKALMELRTKLRNEEEAESPGGFGFLSEFEEFVAEETEEKTLSNSQTYESVAVDFLRDERRFIRELNRINVFRRRIESVAATDVDKQIVCNLFGNLTEIHDLALKIERTLEDAIELSDTQCIGMGIWEHGEAYEFDTYTFYIRRDGGEMNETRHATYVINDNIKALLESERFASLFQSGEHYLGSSLDGQSFRLAVQYVLPQLLHIPIFHIYQYHEYITRLHQLSSSEEDRRDLNDCRSAFERVVGCVSDMSPELKTKITQFLDQQAKSEKIYNVKRLNEIQSSIDGFTGSPIGKTCNELEKDGDLGMIRPSLQFSSEITKNKKWKTERFVYIFDQMIVLCKRHRNTLKFKDRLAVHSIDVFDIPDSEVTNCFKIESHDKSSLPKIYHFVCKNPEEKRQWMAVLVKVTTKSVLDRILDNHEKEEAKRIPLVVPGPDQYRFSEPDTEDNISFEDYTSSSGIPVIKCGTVLKLIERLTYHSYTDSKYILTFLISYRSFCTPNDLFSLLLERFNIPTPKKLQQPKQGGGPLAGRYDTVQSHGLSAISSSSCINPLCEQKFRKEFQQPIQLRVLSVINQWVKLHWYDFQCDPVLLDALELFLNRCCDPREGLSKQHKKFCKTILALIEKRVKNPPGIMQQPNENGDKGAADEGHVNSAFVFGDDQQHPPQHQVYTNESPKETNQVLWHTAQKGDVDHYDLLTLHPIEIGRQLTLLHSDLYRAIQPIELVEAAWTKAEKWRKSPQLLRLTDHSTLLTYWVSRSIVETESLEERMAMFNRVLEVMSVFEELHNFTGLVAFYSALNSSCIFRLKWCWDGLDNEKKKCFDRFNTLCERRWQEMQKRLSSINPPCIPFFGHYLSNIYFLEQGNSTFVNKSPPHGAAGAQKQQKDDLKASDPENSNKQFKQLVSFLKLRKISNVIREIQIFQDQRYSLTLEPTIRQFFESINPKNDFKSNEDLEEYLYNKSLEIQPKGLDTPTAELKPKHNASTLRSPGVKPPKAAGNHYSANHPIGLHLHSQNSHSAPHAMSSQSSTVPNTPLSAHETKRSLSHNQDDAPLQQFVDIRFERKGTHPKIPVLQPPPLLPRSSRANQSNSVSLPPTTQAPMPPAPKSSGMMSTATSPTTLTTTTTPSSAGGPPPKLHPRRMTQQPMSPLAKSPLTPSRDNSSPSAFQFPVVYEASTAPPLPPRPSTSSDVSSSPSTSGSTSSATKENQEQLRVIFDREESHSPTVRLSVPLPPALPPPRGSSVFRAPPPLPPKSNRHNSNSPTLSSEQPFEDPMSPSIFVNTPPPPLPPKTYRSSNK
The following text describes a protein:
Function:
Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
Sequence:
MADPLLSSLCRICHINPTKYTCPRCSQQTCSLPCSKRHKVWSSCSGIRDPTVYKPRSQLATPSGIDHDYNFLHSIEHRIERSEREIVEERGLVKKMELELARQGQTDDRRRPNKTVGHQREDFITKMLQNSGITLVKAPSGMSRNLENTSTWSRTQKCMNWQMEWIREPDAGGRILHKSIDKWSINDTYSVLLEEQRRLNMAPEEKVALKKRKANELKENKAKRIKSDEHSLDIPPLSSFQDSTGAWNVVLDQPTILTDQDSTYQASTPRKLDPKYHFYLHRPKTRSSYPKVLVPLDPTQSISKVLENRTVLEFPTFYVFETDKLSDTFMLEKDYIEATEDGPEMESEESEDEDTSSSDSSSDEDEDVEMEDGEIAP
The following text describes a protein:
Function:
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Subcellular Localization:
Secreted.
Sequence:
MPASSPGNMGGSVREPALSVTLWLSWGAVLGAVTCAVALLIQQAELQSLRREVSRLQRSGGASQKRGEPPWQSLWEQQSPDVLGAWKDGAKSRRRRAVLTQKHKKKQSVLHLVPINITSKADSDMTEVMWQPALRRGRGLEAQGDTVRVRDTGIYLLYSQVLFHDVTFTMGQVVSREGQGRRETLFRCIKSMPSDPDRAYNSCYSAGVFHLHQGDIITVKIPRANAKLSLSPHGTFLGFVKL
The following text describes a protein:
Function:
Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.
Subcellular Localization:
Mitochondrion.
Sequence:
MLSRSPALRAHRSCSHDLLRPVYNLPRPATQLLRCGAANCIAQRLKSTLSRRAPSPTSHTISLRSAFSNSSKRWQVGRRHVSSNTPSDTHPYADRKDAIYALIDKINETELELAELMDDLGLLEEYQGALNLDGPEPDHVFSHWIGHRDEQALESRVRSARQEFGEYLPAGYLNETELRLYTRLYGEPIIKVEEPQSELEAESSEEDRDPNRLFQEDGQGGWKEVEFERGESQDDGPPLVYDMDVGPPVEESAAMRRTREVAEQLGGELMLEQFEDEAVPDAAPRLHPLTRQGKFSTDPSTVFLPKDTVTGPISVILSEYSNKHIADVAHRTFGGRLLPHSTTTPPPRAQVPQLPIPLEASQRHMSQMEGNVYMAALYPGMYASALSVLVEVRKRLGTNWIRRLMAQQDGPHVLDAGAGGAGILAWRDVLRAEWEAMVPDHPETDPIPLGRSTVVTASEALRNRASVMLDNTTFLPRLPDYIHVREKPTLDDERPPPPRKQYDVIIAPHTLLGLEEEYMRKEHVENLWTLLNPHGGVLILLEKGHQKGFEAIAGAREMLLKRYISSPGSTQYDELTESPNENKHIDKEEGMIIAPCTNHAKCPMYTVAGHAKGRRDFCHFEQRYIRPAFLQRILGAKDRNHEDVKFSYLAVQRGVDLRKEMNIVQGPEAAEAAFAGYEHLHDMESEDAQVSDDAATSEPSAAQDGRDFHTLSLPRAVYAPMKRRGHVIFDFCTPAGKIERWTVPRSYSKQAYRDARKARWGDLWALGAKTRVPRSLRLGAKHGEGKKERLEKRAASKAALGESEDGGLESAPSDNWDVFTTPVRKKGQTIPSWKKHQDKKKIRQASKKQSTVKLTDHDLD
The following text describes a protein:
Function:
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
Sequence:
MNLNFMPLLHAYNHASIDFHFNSSARDFCVHEVPLYEFSNTGEHAVIQVRKSGLSTLEMLQIFSQILGVRIAELGYAGLKDKNALTTQFISLPKKYAPLLEKNTSNFQEKNLKILSLNYHHNKIKLGHLKGNRFFMRFKKMTPLNAQKTKQVLEQIAQFGMPNYFGSQRFGKFNDNHQEGLKILQNQTKFAHQKLNAFLISSYQSYLFNALLSKRLEISKIISAFSVKENLEFFKQKNLSVDSDTLKTLKNQAHPFKILEGDVMCHYPYGKFFDALELEKEGERFLKKEVAPTGLLDGKKALYAKNLSLEIEKEFQHNLLSSHAKTLGSRRFFWVFVENVTSQYVKEKAQFELGFYLPKGSYASALLKEIKHEKGENNDEF
The following text describes a protein:
Function:
As part of the mitochondrial 3' processome (MPsome), involved in the maturation of guided RNA (gRNA) precursors.
Subcellular Localization:
Mitochondrion.
Sequence:
MKKAWAQLERVLQPSSSRVNRALITQQLEALYALPINCEAACRWEDAQRLFLRCNGHRPYYAGIMDQSTDNRLAVASFEENMLALQQRGLVCTTVGDKAPPCVVGGQTSRGLCRRSSIVCVNVGSCADLDLNMHEDCDETLLTLLHGVVVPYLHFRIVYGTGVSPPLVPRAPGPAICGASHDLSLQNELHMDSCVALLHPRGLCSSNCNNKAYRTAATLVRGAVSLATSDTLLHQRQDGCFTLHPDAMKLGSPRLFALQLWWNKEVGPVIQRGVEQSVKTDEVLSGAWIEVARKRVEELVERGGDDLPQPLRNMTRDDVAAFAADATLCWTLSAFDCNYKRLGPAQPACRLQFSEEARLSMALELMQTVKASLVKQPTGIPISELSATVCWPAASAWIGEKSLTEALTQFPAHFNVVNVEGKLVVMHGHLTGPSDNVTAEEVSEWLAAGHSEGLQKPCVAASPSDLTFHRETDLVVRAVAFLRKRHFGNVPVTYGELCGALLPKNNGKNDGDSDTLLNVLLRYDVLAADTAKGDSSINIQCGLRDGDAIRLSVREDRALRALEAFRTTSRSAFQLYTEAIEPFLTCCRGAMRENGSCVVPLTLLERWLQVERLSLQSKELLDILRSAEGPYRIDEELCNVVLTNHTAKGEVLTPAFSLPATPPPPPPPAVSSRLTFEAQISRVLKTQRPDRLLHFVQTILHAVFDLILPHVSAPSGVPVRMLMRRIRWGSFVVTLGSLTSFVEAFDGLFFEVLSNASSHGEEKRDDVDLIVSAYKGPVSPWLLYARLIVRLFPADVDIPLGLIAEALSWSSRFAPMFGDLPSLLRRVGRQCRNGQLLAKVEMVRPVCDQDDACLWELLAKIRREAHLHHLERSSGETGQYVLLSETELYAYLPNDVKGERWNSTVKEEGARCLATMAVHRLPHFFEWHVDNTDTTTRYVRVVLPFSTPPTGVVCFVEEYVCPLLRQHKQTTIAELDEQLGWSHGAFDAHPAGSQAAGGTPSATSLCGLLRRYVESMHSPKIILEPQETTLSPLHHHVHVMPNSAVYTSPEDMLLLLNGLRISNEGITRVLPTHKPVSLFELISQQLDLHQPFREGLTTLERGSRWNVMLACESDSMDDCLQELDNCTGDILVWCEG
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein.
Sequence:
MFPLFCFASLASAAHKTLVLLGEDTDDLQFKTFFEDLKKYSSVVDTRILSDDKTDRIILERFGSRLYDTIVIIGSKRDAFGKDSEILTHFLDNGGNAIVFGTGAINSVQEFIARHLGVHIEKKPVQDLYGNNDIVLRKLVAPETVVSGKINPVTYNGGFLVISRPNDFQMPIMVGGLQHIGIPTIRSFKKLYANQIVPIAAFQGRNGGRITFICSETFAHDSSLNSEVRFAEDLTEIPAEKSGNHDLLIQLLEWTIHYKSYNKIVSATHYDPATKEAPVQYTYNQSITVVAEVSTANKGEFVPYTDELQAEIFMLGTFVRRHMKMVSPGKFEVTMNIPDKHGNYFIKVFTDKFGYYNAREEMAIAVRPLSIREKEHFLFAAKPYVASCLSIMIGAFLLTCHFLWHKPSN
The following text describes a protein:
Function:
Probable transcription factor that regulates carpel integuments formation. Required for the specification of polarity in the ovule inner integument. Modulates the content of flavonols and proanthocyanidin in seeds.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing KAN4 show reduced or absent ovule outer integument and color alteration of the seed coat.
Subcellular Localization:
Nucleus.
Sequence:
MMMLESRNSMRASNSVPDLSLQISLPNYHAGKPLHGGDRSSTSSDSGSSLSDLSHENNFFNKPLLSLGFDHHHQRRSNMFQPQIYGRDFKRSSSSMVGLKRSIRAPRMRWTSTLHAHFVHAVQLLGGHERATPKSVLELMNVKDLTLAHVKSHLQMYRTVKCTDKGSPGEGKVEKEAEQRIEDNNNNEEADEGTDTNSPNSSSVQKTQRASWSSTKEVSRSISTQAYSHLGTTHHTKDNEEKEDTNIHLNLDFTLGRPSWGMEYAEPSSDLTLLKC
The following text describes a protein:
Function:
Triggers photoperiod-monitored flowering by repressing PHYB-dependent flowering negative regulation, probably through physical interactions with PHYB and CO.
Subcellular Localization:
Nucleus. Nucleus, nuclear body. Cytoplasmic granule. Cytoplasm. Note=Circadian clock-regulated subcellular localization. During the night, mainly present in the cytoplasm. During the day, moves and accumulates progressively in the nuclei.
Sequence:
MGVSFKISKVGRKFRPKISTELATPDSPKAIVLSGKPKATDDSNIGDVSGFSKPSLPDISPDHEVSFILSLYPNGYSIGKTSEAMQQISFRDVPKVLHPYDRAAEGLLSAIEAGRLPGDILEDIPCKFVDGVVICEVHDYRKHTSSQVSPVINKLRLKMSLENVVKDIPSMSDNSWTYGDLMEVESRILKALQPELCLDPLPRLDRLSKNPLTAKLDLSLSTLRRKRLRQMAEVTVMSQNKIQGKKVCIDRLPESSERGNLPGHLIMQQTNNNQAIQNLGTNMLAGLRSQPLQDAPNSSLALVPPQQQRYMGIGSTRNTQDQGSNSVSVSGASPGGLDAMLPYGSDSMNPGTSFHRKRESQEGQMSSMPGLNKRTRVSHMGPDGVPQQQLGQRMDGLHGSDTNWKNTLLQHQDMLGRSIQYPNTSIQRFSPHQMEGVMNQEGGPMQFPASQQGGMKYTSKEEPFETGKIDGGTRNNIPGVGSDANDLDPRIQSRMPHNAFIRSNFPQTSWNVNPGQQIEKEPKKEEQFSRRISAQSPRLSAGGPPQSPLSSKSGEFSGGSMGTHYGAVAAAQKDKAVTSIPAIGATQSVGSSANEAMQQRQHQAQMAAKRRTNSLPKTQVISTVGSPVSVNTISVPVNARSPSVGPQTLGDHAILDRFSKIERVAARYQLNCKKHKVDEYSRRPRVYAKQPLTVCLSNLSNEEVFKDEDEALSKSIFGGSMNTYKTRVIHFGQMERVMQGSVPSFIPRNRTRLVMSEKAVDGTVAWYQGDVDEGDVFQAEDFLLALPNTHIADLLATQFKSLMAREGYMIEEHIMAKPNRGDTGPISSHPNSAGGYPRGYSANDMQQYGDAVAGQASGEASKHGNTGNTPNNSTQNILANARMVPPTNSQALQMSQGLLSGVSMPMQPQQLDPQQSALLSSHSQQKNQQSMFTQQQHPQMQRPSMILPTNPLSAINSMSQSSGMQPGGQMANKYSPLQLQMLQQQQQAAVQKKIMMGLGSGVGMGMGMGMGMGMGSMGNSIAGLGALGNQLNMAGRGMGGTGISSSMSVPGIGNMGQNPMNLNPASNLNAISQQLRSGALTPQQNALFTQIRMGMANRGGVMGAPQTGISGVSGTRQMHPSSAGLSMLDQNRANLQRAAAMGNMGPPKLMPGMMNLYMNQQQQQQQLQQQPQQQQLQHQQQLQQPMSQPSQQLAQSPQQQQQLQQHEQPQQAQQQQQATASPLQSVLSPPQVGSPSAGITQQQLQQSSPQQMSQRTPMSPQQVNQRTPMSPQISSGAMHPMSTSNLEGCPASPQLSSQTMGSVGSITNSPMELQGPKNNSAGNNS
The following text describes a protein:
Function:
Histone methyltransferase. Specifically methylates 'Lys-36' of histone H3, inducing di-methylation. Plays a role in modulating lifespan and oxidative stress resistance, in a manner dependent upon daf-16/Forkhead box protein O and the Insulin/IGF-1-like signaling (IIS) mediated pathway. Represses transcription of daf-16 isoform a, perhaps by methylating histone H3 at the daf-16 promoter, which in turn leads to recruitment of histone deacetylases and thus modulation of expression.
Sequence:
MAVKKNKNVPKQEDPLVQKDEISSIHARIKIFETPFATQVLNPKVSEFCANCLRGPAPGEKLLRCGGCNFSMYCSKECQATAWLVHKPECKRLKASFPNLPLTEVLFLSKVIDRIQFLEKNGDKLGIEAERKFSSLVDHKVDIRDDEEKMAHFEKIFEKMGAFRGEEMIEKGEFFDVFCKATINSHSIHTNAGNEVGMALDLGVSKYNHSCRPTCSMVFDGYRVCLRPLVPGVDAENTEEAFISYIDVGRSKYIRRRDLNSRWYFNCECTRCMDPEDDALTAIRCANPACDAPILTSETEEPMNIACEKCKTIVEEDTVKAAQEYMKTLPASFDPKCPAEIEALPGKLKELLAKAEQILHPSNVYVARLRTALFHVTGTLTMDNLSSMHTQIYNNYKMCFPKADRHVGFQLLHIVKALIEKDERDEAMPYAFDAMNIFEVCFGLDHPYYLQTLALWTYLEKKIPKSTEELVQLTNFSDNRPIDIVSLLKRANMLPPPPYAAGTPGVA
The following text describes a protein:
Function:
Acylhydrolase that catalyzes the hydrolysis of 1,3-diacylglycerol (1,3-DAG) and 1-monoacylglycerol (1-MAG) at the sn-1 position. High activity toward 1,3-DAG and 1-MAG, but low activity toward 1,2-diacylglycerol (1,2-DAG) and 1-lysophosphatidylcholine (1-LPC), and no activity toward phosphatidylcholine (PC), monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG), triacylglycerol (TAG) and 2-monoacylglycerol (2-MAG). May be involved in the negative regulation of seedling establishment by inhibiting the breakdown, beta-oxidation and mobilization of seed storage oils.
Subcellular Localization:
Cytoplasm.
Sequence:
MKRKKKEEEEEKLIVTREFAKRWRDLSGQNHWKGMLQPLDQDLREYIIHYGEMAQAGYDTFNINTESQFAGASIYSRKDFFAKVGLEIAHPYTKYKVTKFIYATSDIHVPESFLLFPISREGWSKESNWMGYVAVTDDQGTALLGRRDIVVSWRGSVQPLEWVEDFEFGLVNAIKIFGERNDQVQIHQGWYSIYMSQDERSPFTKTNARDQVLREVGRLLEKYKDEEVSITICGHSLGAALATLSATDIVANGYNRPKSRPDKSCPVTAFVFASPRVGDSDFRKLFSGLEDIRVLRTRNLPDVIPIYPPIGYSEVGDEFPIDTRKSPYMKSPGNLATFHCLEGYLHGVAGTQGTNKADLFRLDVERAIGLVNKSVDGLKDECMVPGKWRVLKNKGMAQQDDGSWELVDHEIDDNEDLDF
The following text describes a protein:
Function:
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Required for nuclear migration in retinal photoreceptor progenitors implicating association with cytoplasmic dynein-dynactin and kinesin motor complexes, and probably B-type lamins; SUN1 and SUN2 seem to act redundantly. The SUN1/2:KASH5 LINC complex couples telomeres to microtubules during meiosis; SUN1 and SUN2 seem to act at least partial redundantly. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. May also function on endocytic vesicles as a receptor for RAB5-GDP and participate in the activation of RAB5.
Subcellular Localization:
Nucleus inner membrane; Single-pass type II membrane protein. Nucleus envelope. Endosome membrane; Single-pass type II membrane protein.
Domain:
The coiled coil domains differentially mediate trimerization required for binding to nesprins and are proposed to dynamically regulate the oligomeric state by locking the SUN domain in an inactive confirmation (By similarity). The coiled coil domains are proposed to be involved in load-bearing and force transmission from the cytoskeleton; The SUN domain may play a role in nuclear anchoring and/or migration.
Sequence:
MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLGPSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVGRKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MRHNMLVVGLILGVILVLSQVSESTHRLNLQIGPIIVGGKGKPPKGSPTTPPTLTPPPPSPTPPPGLKVGFYKGRCPNINVDVEANIATKVQQEFRKDPTILPALLRMQFHDCFIHGCDASILIKGSSSERTAGPNLSVRGYELIDTLKNVAEATCPDTVSCSDIIAIATKEVLKMGGGLGYAVETGRRDGLVSKAQDVDLPSPFASVSESISAFAAKNFSPEEMVILLGCHTVGISHCDFFEDRLYQGSSQFDENMDKDLREELKPVCPQNAGSDNFTFLDQNSESSNIVDNSFFQQIVKQRGILPIDQALANDPQTSGFVQQLAVNPNMFATRLTTVMVKLQALDVLTGNQGQIRKVCSKFN
The following text describes a protein:
Function:
Catalyzes the conversion of L-arabinose to L-ribulose.
Sequence:
MDVFKQSEVWFVIGSQNLYGPKTLQQVMDNAHQVVNSLNNEAGLPVKLVLKPLVTTPDEITALCREANYDTACIGIMTWLHTFSPAKMWIGGLSILNKPLLQFHTQFNAQIPWKTMDMDFMNLNQTAHGGREFGFIGARMRQQHSVITGHWQDKEAHQRIGQWMRVAAAKQESQQLKVARFGDNMREVAVTEGDKVAAQIQFGYSVNAYGIGDLVAVVDAVSKGDIDTLVEEYEATYRFTDAVKLNGDKRENLLDAARIELGMTRFLEQGGFKAFTTNFENLYGLKQLPGLAVQRLMQQGYGFGGEGDWKTAALLRILKVMGTGLKGGTSFMEDYTYNFQPGNDLVVGSHMLEVCPSIAKEEKPLLDVQHLGIGGKADPARLIFSTPAGPALNASLIDMGNRFRLLVNVVDTVEQPHPLPKLPVARAIWQAQPSLATAAEAWIIAGGAHHTVFSQAVGVDELRLYAEMHGIEFLLIDNDTTLPAFKNEIRWNEVYYQLNR
The following text describes a protein:
Function:
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. Complexes with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability. They are necessary and sufficient to promote functional reconstitution of odor-evoked signaling in sensory neurons that normally respond only to carbon dioxide. Involved in the behavioral responses to acetophenone, benzaldehyde, benzyl alcohol, cyclohexanone, and cyclohexanol.
Miscellaneous:
MISCELLANEOUS: The atypical heteromeric and topological design of the odorant receptors appears to be an insect-specific solution for odor recognition, making the OR/Orco complex an attractive target for the development of highly selective insect repellents to disrupt olfactory-mediated host-seeking behaviors of insect disease vectors. Odor-evoked OR currents are independent of known G-protein-coupled second messenger pathways.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTIEDIGLVGINVRMWRHLAVLYPTPGSSWRKFAFVLPVTAMNLMQFVYLLRMWGDLPAFILNMFFFSAIFNALMRTWLVIIKRRQFEEFLGQLATLFHSILDSTDEWGRGILRRAEREARNLAILNLSASFLDIVGALVSPLFREERAHPFGLALPGVSMTSSPVYEVIYLAQLPTPLLLSMMYMPFVSLFAGLAIFGKAMLQILVHRLGQIGGEEQSEEERFQRLASCIAYHTQVMRYVWQLNKLVANIVAVEAIIFGSIICSLLFCLNIITSPTQVISIVMYILTMLYVLFTYYNRANEICLENNRVAEAVYNVPWYEAGTRFRKTLLIFLMQTQHPMEIRVGNVYPMTLAMFQSLLNASYSYFTMLRGVTGK
The following text describes a protein:
Function:
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
Sequence:
MKIALIAHDKKKNDMVSFAYAYKPIFEQHELFATGTTGLRIMEATGLVITRYQSGPLGGDQEIGAMIAKNDLDMVIFFRDPLTAQPHEPDVNALLRLCDVYAIPLATNMASAEMLMHALERGDLDYRKLRK
The following text describes a protein:
Function:
Formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of transfer RNAs; at positions 34 and 36 of intron-containing precursor tRNA(Ile) and at position 35 in the intron-containing tRNA(Tyr).
Subcellular Localization:
Nucleus.
Sequence:
MTSISKRKNQQEHIPAEDLETPKLPKREKIEGTKESNKVRIIILLGYSGYGYHGIQINNPLKTIEGDVVAVLKKLGYLKTNNIDAEHLCIARAARTDKGVHTLRNLISLNLFVDKPLDISLLKTELNEALCSQIRVWSVFPAPKYFNPRISCESRTYEYLIPSFALLPPKPSCPLFKKMQKNLSRKLDNELERNLVYSMNDLISFWNTVKLKQKEIQEMFDTNKDAFTNPFKGMFYEKPIPAGIVIPPQAKLKKALKQAEYYCYMNYRIKEDRLKVLQQLLKKYEGRHNFHNFTVTDDSTSPSNYRFIESVTCGTPFVYENWEWIPVTIKGNSFMLNQIRKMMAHVLMIIRSCAPTGLIDKAFDPNITMNISKSPGHVLLLKDIKFSSYNDSVTDGLEKIQFDCFEEDILSLKIKTIYPDIIKLEQKEKLFFSFLSYIDQHTGHQFDYLFG
The following text describes a protein:
Function:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MKVTIKTIKDGTFDLQMGDDATIGEVKAAIEQSKGDKYPKDGLKVIYQGKVLGDSDTLASANFQEKDFLVVMASKAKPKPAATPAPAEPTASNSAAPSAAASTEQPAQSAQSASGAASEDDVNRLMNMGFDRPQVEAALRRAFGNPDRAAEYLTTGMPAEEAPSMDATPDEPAGGEGEAVVPQELSEDSPLYFLASNPSFLQLRQLVQEQPHLLPSMLQQIAASNPDLVSLINENQEDFYILLNAEDENGGAPMPGAGGAAGAGGSGFPGVQLTQEEMAAVERLSQLGFDRNLALQAYIACEKDENMAANWLLSNGAGMS
The following text describes a protein:
Function:
Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Domain:
The N-terminus is required for efficient association with MHC class I molecule and for a stable interaction between MHC I and calreticulin. Binding to TAP is mediated by the C-terminal region (By similarity).
Sequence:
MKPLSLLLAVASALGTAVSAGPAVIECWMVEDAGGGRLAKKPAALLLRQGPGTPPPRPDLEPELYLKVHDPAGTLQAAVRRYPSDAPPPHCELSRFIPLPASARWARGLTPGRSCPRALDGAWLMASVLSPIFSLSCLLRPQSEPQPEPALFTSATAVLTVLTYSPIAQIQLGQDALLDLRFAYMPSISEAAASLAPGPPPFGLEWRRQHLGKGHLLLAATPGLHEQMPAAQDGAVAFAAWDDDDPWGPWTGNGTLWLPAVQPFQEGTYLATVHLPYLQGQVALELSVQKPPKISLTPAPLVWAAPGEAPPELLCLVSRFYPAKGLEVEWELRGGPEGSFQKAEGQSWLSALRHHSDGSVSLSAHLQPIPVTAKHHGARYACRVHHPTLPTLGRSAEVTLEVAGLSGPSLEDSVGLFLSAFLLLGLIKALGWVAASRSTSKDPKEKKAQ
The following text describes a protein:
Function:
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MVFIILDYFFVRMLIPVRCFTCGNLIADKYDDYQNKIKAGEDPEKTLESLGIERYCCRRMLLTTVETIQQVIPFYEAIQRRKQEVQSELE
The following text describes a protein:
Function:
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKHRLQQVADTMQRVLGDVIQKELKDPRVGFATVTGVEVSADLQHAKVRISVMGSPEEREAAMAALQRARGFLRKRVAEEMSYMRFVPELHLIQDTSLDYTMHMDEVFRAIQHERLVNPPKLDDEQ
The following text describes a protein:
Function:
Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that repress transcription.
Subcellular Localization:
Nucleus. Chromosome. Note=Localizes to condensed chromosomes during the diakinesis phase of meiosis.
Domain:
The CRC domain mediates DNA-binding. It contains two CXC subdomains (joined by a flexible linker) which are both required for efficient association with target DNA. Each CXC subdomain coordinates three Zn(2+) ions.
Sequence:
MNQGEIVYQDDDDYYDESEIYDNYEEGAEFIEVNGQLVPHNPNLQAQQNRPGTSSMIQQHNRSMEVNQGLVKDEPIDTSSHRVYVPPPRPVQRKLFQPGPSTPGSSQYTVRNLSNLSGSPSMYDRQPASLPRTVQPMGLEMGNSEQRKVYIDMKDHVSHIRLKTKKKVFAPGQRKPCNCTKSQCLKLYCDCFANGEFCRDCNCKDCHNNIEYDSQRSKAIRQSLERNPNAFKPKIGIARGGITDIERLHQKGCHCKKSGCLKNYCECYEAKVPCTDRCKCKGCQNTETYRMTRYKNSGGAVSNTNALMSLTNASSTATPDSGPGSVVTDEHGDDYEDMLLSHKPKVEMDPRRFPWYYMTDEVVEAATMCMVAQAEEALNYEKVQTEDEKLINMEKLVLREFGRCLEQMITNTTELTQDLDAAPTDDIPGPSTSTS
The following text describes a protein:
Function:
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
Subcellular Localization:
Nucleus.
Sequence:
MGIQGLLPLLKPIHRSVNISEFKGQTVGVDAYCWLHKGAYGCAMDLVEGKKTTVYINYVLKRINMMLFHDVKPVLVFDGAYLPSKANKEAERRKSRNENKANGLAFLRAGNRAKAQECFQKCVDISPDMALEVIKMCRSKGVDCIVAPYEADAQLAYLMKKNIIQAVISEDSDLLVYGCKKVMFKMDASGYGTLVSLDHLSELTNLKMHEFTLEKFRHMCILSGCDYLPSIKGIGLIKANKLLRNSSNINKACINLTLVRNLRMDDQYRVPVDYEKSFKQADETFLYQRVFDPVSCELVPLNPIPE
The following text describes a protein:
Function:
Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration in response to chemokine stimulation.
Subcellular Localization:
Cytoplasm.
Sequence:
MATPGSEPQAFAPALSVTALHPHLHQHHQHHQHHQHHGGTGGTGFNLPLNRGLERALEEAANSGGLNLSARKLKEFPRTTAPGHDLSDTVRADLSKNRLVEVPMELCQFVSLEILNLYHNCIRVIPEAIVNLQMLTHLNLSRNQLSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPPELVDLPLVKFDFSCNKVLVIPVCFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTSDSLYLPTIERPHLHQHVEDSKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNAPMSNIVEEDQTIKEDACHRLTPTKGEFQPKPSILGDSGISGQEREQLAGRADARHSGLMNYIKDQAEDCEELLRIEEDAHWHMEELLNSSKDRELDIAMIEQLREAELLQDPNGLSADIIERSILNLFPMDSGEASEFPDPSLNGQLQLETSPDREVQNDLMLQSNGSQYSPNEIRENSPSVSPTANITAPFGLKPRSGSWCPEEVQGSLQAESSPRRPQLLSRHVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVTLHEDLGAALMDGVVLCHLANHVRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEEKLCLPHHILEEKGLVKVGTTVQALLDVTVTKALFT