lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Actin-associated protein that may play a role in modulating actin-based shape.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MVAEEVIITLSGGAPWGFRLQGGIEHQKPLQVAKVRKRSKACRAGLREGDELMSINENSCGSLSHAQAMNLIDSMPGTLHIRVRRAMSPSSSRPHQSSVRQIHRGTLMSPTGRSGLTSPPGSEAYYGETDSDADVAAHERHRKPKRRSPSNSPGKAGRASPEGAETSEMSGYDSASDAQMYKLLGPNKREDTLPGVARREVIYQPPLHGAWSSQTSTETSSMSADDQNPREGLMEEDSGFQEPTNIPPLVSPERAKEALMLSSRSQLVPMVGPVDNPVDEELTLTYMDKAKQAKLNRGETITDKQVKEARSKCRTIASLLTDAPNPHSKGVLMFKKRRQRSKKYTLTSFGSVDEDMRQDSQEEDGIFPGSESEFDEEGFSAAPDPTWDSDYLEMLEKRCASRGQEGDGGALSPGLSDTSGKGAQLFEQQRKRAEEHARKIEAAQEQLQSQMLGISLKEAQALPPLQTAHPDPLTKLNVQPPPVAPKPARPSTTLYHDVQAAEAQNNKTQMNTPQTIPTVPVMVNGDASNTTVTAPSVMPKTNLSVLSTETVMPPPPTPLPELPASSVLNRTARPFAPGCITNRAATAPVVFRPAVSKKTPRPVSVAVVAPPFPAASEEHVMCVTPAIFGTQVTMSQMNANVSNEIIPTQPLAQGTSIPPPAAVSVESYSQSAFQCSPMESIQVASLPRVQAQKPTVPMIAETIVPPDDMVTSLATDMHPKGIAISSQTSSILTPTASETTSSPVIPLSPVVYREKPASVGGRTGILQDARRRSAYKPMFKMPDSKKNSPNPELLTMVQNLDDRPSHGYPEPDNIVYNIDENRTRVPPPVAPKPRVIPEMSQIPQAEGKGAELFARRQSRMDQFVVDTPYLQPATLQHQQSQSVIDLIQPRELSPTPSQWKYSPNVRAPPPIGYNPLLSPSCPVGVQRAGAKVSEGSAKGSKGSYGVPKEGIKALDFMRRQPYQLNPAMFSFGGGIGTQSSIPSYQRQQREGHTLTPPKQIPVKAARVYEIKRFSTPTPMSAPTLNPTVIIPRSQTTLGERISRSDMTSPPPEPVPETSLAPSRAPGLPELPKISSVPIPHPMPYSPPVPISSMSNLSYSGLQAAKQFKSAPELSALPPNPLKSPIQVPKPHFIATRAGVQPRVWRPGTLPH
The following text describes a protein:
Function:
An iron-dependent alcohol dehydrogenase required for optimal 1,2-propanediol (1,2-PD) degradation. NAD(+) and NADH are regenerated internally within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by the PduP and PduQ enzymes, which reduce NAD(+) and oxidize NADH respectively, although there must also be cofactor transport across the BMC; The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
Miscellaneous:
MISCELLANEOUS: Bacterial microcompartments (BMC) 100-200 nm in cross section are formed during aerobic growth on minimal 1,2-PD-B12 or anaerobic growth on 1,2-PD-tetrathionate medium, but not during aerobic growth on glucose, anerobic growth on glucose or pyruvate-tetrathionate. BMCs can constitute up to 10% of total cell protein.
Subcellular Localization:
Bacterial microcompartment. Note=Probably located inside the BMC shell.
Sequence:
MNTFSLQTRLYSGQGSLAVLKRFTNKHIWIICDGFLAHSPLLDTLRNALPADNRISVFSEITPDPTIHTVVQGIAQMQALQPQVVIGFGGGSAMDAAKAIVWFSQQSGINIETCVAIPTTSGTGSEVTSACVISDPDKGIKYPLFNNALYPDMAILDPELVVSVPPQITANTGMDVLTHALEAWVSPRASDFTDALAEKAAKLVFQYLPTAVEKGDCVATRGKMHNASTLAGMAFSQAGLGLNHAIAHQLGGQFHLPHGLANALLLTTVIRFNAGVPRAAKRYARLAKACGFCPAEANDIAAINALIQQIELLKQRCVLPSLAVALKEGRSDFSARIPAMVQAALADVTLRTNPRPANAEAIRELLEELL
The following text describes a protein:
Function:
Probable methyltransferase.
Sequence:
MSSIPDHNNNNNNNNKNNNEILNFKQLFKKIEEFKQLGNQEFSKYDKTNDNLNKRAVTYYSLGIECFNDNFEKLKNNNNNNKDDEIELKKLVSIIYSNLSLCFINGYEIDKALEFANKGTEIDKDNSKCHYRKSLCYQYMCNFKESFKSINDALNSINNNNNNGKVIIDKSLKQIIENERKEIEKKLKKLEKEEKESQDRIKEDFEQFQQFPIELVWRDGFGRCVLASEDLPKGTMVLRVSPFASVLEDHKIEKNCGFCFKKINKSIRINQTCKNCKNHLLCPQCSVDEYSLNYHKDECDILNFLKQYYPSSQTRDFRFMFRVLLNVIKDKKNKSFSKENQSKQWLNHQNPFIFDSYKYLINLSRTLDKVQPEQMEAFKRSAQSVIAIFNKLRGPKFFDECGVTIDEIIEIYSIVLSNGHEMLHPLNCHTYGLGIFPTGSYLNHSCLPNAFWYNDDQGMMVFRTLRPIKKGEEILTSYTDITTECSERRKHLLKQYFFFCQCQQCKFQSKLTDQSCLSCKNQLSSSNTSFKIPSNDSIESGFYYHCLKCNSDNKQINCPDDSSSVFTSQHDQRTFKKINLLINIMQQRHQSIATNLLNTNNEYLMKGMPDHIVYKEITNALEQSMISNPSKVSADQVFTNSLIQYYFRLFQTLKIEKPNDTQQLQSVKTKILQLLTPIIHLPTSHHKSSIEKKLKF
The following text describes a protein:
Function:
Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S (By similarity). Targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit.
Subcellular Localization:
Mitochondrion.
Domain:
The MTERF repeats form a half-donut shaped, right-handed superhelix, where the concave side displays a positively charged path for nucleic acid interaction.
Sequence:
MASLGRQVPEWHRLLALSWACLVRQTPHLREQKQMSPSLSCKLTTVPGRGSFQEFSSITPQKYMQEPENRTRLVQCLHEEQKPCVDPESLEPEKVIRSLQDMGFAEAHIHSLFSIQPSVHPQQLLGIVSELLLLGLNPEPVFNALKKNPQLLKLSSMQMKRRSSYLRKLGLGEGKLKRVLSVCPEVFTMHQRDIDRVVKVLREKCLFTAQHITDVLHRCPTVLQEDPNELEYKFQYAYFRMGLTHLDIVRTNFLQYSITKIKQRHIYLERLGRYQTPDKKGQTQIPNPSLRNILRVSEAEFLARTACSSVEEFQVFKKLLDQEEEEESESHASEEEEEEEEEEELL
The following text describes a protein:
Function:
Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A. Binds 25-hydroxycholesterol and cholesterol.
Subcellular Localization:
Late endosome.
Sequence:
MNTEAEQQLLHHARNGNAEEVRHLLETIEKNEVIADINCKGRSKSNLGWTPLHLACYFGHRQVVQDLLKAGAEVNVLNDLGDTPLHRAAFTGRKELVMLLLEYNADTTVVNGNGQTAKEVTHDKEIRNMLEAVERTQQRKLEELLLAAAREGKTAELTALLNRPNPPDVNCSDQLGNTPLHCAAYRAHKQCALKLLKSGADPNLKNENDQKPLDLAQGAEMKHVLVGNKVIYKALKRYEGPLWKSSRFFGWRLFWVVLEHGVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKSTDSCLFFIKCFDDTIHGFRVPKNSLQQTREDWLEAIEEHSAYSTHYCSQDQLTDDEEEDEVSTVDVKDSLEKAQTCQQRLDREISSFLKMIKECDMTKEMLPSFLQKVEVVSEASRETCVALSDCLNLFTKQEGVRNFKLEQEQEKNKILSEALETLATEHHELEQSLVKGSPPLSILSEEEFYDALSGSESERSLSRLEVTAQSFEEEGEHLNSRNHRMSEGKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLADPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEITNHKTGDKCILNFKPCGLFGKELHKVEGYIQDKSKKKVCALYGKWTECLYSVDPATFDAYKKNDKKNTDEKKNSKQMSTSEESDEMPMPDSESVFVIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYSGAQDWLYSGSYWDRNYFNLPDIY
The following text describes a protein:
Function:
Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
Domain:
Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.
Sequence:
MTSPRDVGQVHSIKERKGKEEPRRRENLSGLRGQTRKTLGLSTTKSFNLSHQLSSTSNRPDSQNRRPILPPLIMASTIFPNSNHQPRVHPYSPSNKHSFAFQSVTTRWPKILTQVIDHLVDQNNQLLDRLPSDPDSQSLKAKLTQGKAIISLISELKYEAARDKELSPLESNQNYTEQENQIILLYNQELSKSKAAGKPTWFSASWLLTECYLYQRLHGFFNRHEHWKNFDPFEHQKLSSFRSSWSAVSNLCLILDRLTKQDKQSSVTDDDLLGRRAQFNELLSACLWGNATDLSLLPNMTHEEIQHLQTSSSRKPESVLRDDSAQVWQTCFDFNSSVPGKPSARRIDFVLDNAGFELFTDLVLADWIVSNSKAAQIVFHPKLIPWFVSDVMKKDIDQLLESMVDPRNFFTSTGTDQSSTNPDQTHDAHFLVVQEIGRRWKSYFESGAWKVMDSSLLSFWTNPLPFWDIASRDTKLLEELRAADLVIFKGDLNYRKLTGDAQWETETPIEEAIGPLNGLFNLLSLRTCKADVCAGLGSGKEAWVSKIDPDWRINGKFGLITFVPKKQAP
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MRKCLRTFLNPKDFYAAQRPVLRVSFLVGMTPFTVVKGPTELMMLRCTPFGYINSSVHVILFCSCYVNALLQGDTITRFFFRTDISTLGDVLQFTIGITALFMTFFCSIFQRNKLIKCFHALASIDRRFKEIGMETNYKSTLHYNLLVMLTKAIISTLYLVVCLAVFISSDTYPSVTTWMAFLLPYFMMSMVIVLFLCFVNQTKHRFHLLNKVLKHLKQAALEKRISPQRRPSYWHAIKIQRPLGIASVYSNNDKSMPDVVSTVAEIQDALCEACSYAEDYFTIQMLTIVTIVFLIIVFNSYYVLDALLGSTSLDSPFSKGQFAMFFLCQAMVYGFGVFNIVYGSSSLVQENDNIGSNVHKLLNAAAGADSELAGKLMHLSLQMLHRKVRFSACGLFSLDFSLIFTLVGAATTYLVILIQYELSMDESKHETIARAFLGNETW
The following text describes a protein:
Function:
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
Subcellular Localization:
Mitochondrion.
Sequence:
MASIVSNLSSTISRLTLLRKPSLQFTIRNLQNFNRHRQFGTPTPHFLHNSNNHATPHFSSSPKPQSTSALGQDEELIVLGIETSCDDTAAAVVRSNGEILSQVVSSQADLLVKYGGVSPKMAEGAHSLVIDQVVQEALDKAKITEEDLSAVAVTIGPGLGLCLRVGVRKARKIAGTYALPIVGVHHMEAHALVARLVERELQFPFMALLISGGHNLLILARDIGHYIQLGTSIDDAIGEAYDKTAKWLGLDLSKSGGPALEQLALEGNQDSFKFKVPMKQHKDCNFSYAGLKTQVRLAIESKNIDATIPIASTSSEDRRVRADIAASFQRVAVLHLEDKCQRAIGWGLKIEPSIKHLVASGGVASNKYVRSRLYNMVEKNGLQLVCPPPSLCTDNGVMIAWTGIEHFRMGRYDTPPPACEPDDALVDIRPRWPLGEEYAEGRSEARSLKTARIHPSLTSQIQASLEKQPL
The following text describes a protein:
Function:
Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. May be required to embody the molecular ruler of the complex (By similarity).
Sequence:
MPLDDDLEDNPSLVPPPSTTTTSSNATGDAATMMDEVEEAEDAPTADFRLFASTYSKTKNISAQTIRKGEKDFESHGTRAQASALDASRDAMRDVLSYTRVHNTKSASGWCRGWYFPDWWKDWPEDWEQQKLTKRGKEGAGEDDEEEKDRKLPPLHVRDRVVLLEHTNVASQSLGRAVTGLPKDRPARGREWLLPEEALYLVERGSLDLWWPTKGIEEVFPADGSVPAAAAATTSAKGEGEQRTEEDEEDDDEYKYGLPLSLQAAYALLIGEDGERGKVSLQKFQVFSHLKRAGYNVIRAPTNPLPVQEDTQLTTTTQPASKPISVTEWLISCLPQSKSSPTDPPPYGPLVPPGFYRSYNTIYNYLSLRPSSTSSSASPTADNQPQKPQSPESDESDSGSDSPYKIHYHVYKASTKFTRTRPPPPDFYISVISAKDTSIPTLSEISSLLASAPADLPKAEWLAGGPARLYARLKHGYRNVLLAVNDHGVINYMRFAEGGFAKEELFRNYDMRVSGGPRRGGGGGGKKSGNNNGRGSRGRGGGRGGGRGGRGGRGRGN
The following text describes a protein:
Function:
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Sequence:
MEELSRRVRPGRFGFALNCPKFSDRVLRIEVVGSVASDAASVAGDASSSSRGHSDESARPLKRSRDEFPAAVSPPPIPNRAVNESPHDDSLGTLPPIVRLKKIHVSSVILAGSSDYFKKLFTNGMLESTQKEVTLRIREAEEMPLQHLLSFMYGEEILTTDPAHIIGILMVADKYQVLSCVTHCSELLTTCPISTEVALLYLNLDCSIPTALEPAKDAAKKFLCNKYQDFLRFEHEIMDIGPSGLAAILSSSDLKVPSEDYLFDFIVNWGRIQYPDRGERRTVFSSLLPLIRYSHLSCGKLSKIMKCQDIDLNVARLPLVRALFFKSDPVSRQHLIDGPEPWSYEQRAYLYRPLEVMQLHRPVKQCMVYMDLNTDDCSKMFPTGSILSEAFHFAKSDFFLTAGCIVQQPGPLHSFGLFLGVTGDCPLPVTVKYEFSARAKPSGDFIVKWSYTHTFTQADVRMGRRNLFSMPWAAFVDYDNNPWFIGGVMYLRAILTLVIE
The following text describes a protein:
Function:
Transcription termination factor required for processing and steady-state levels of plastid transcripts. Required for splicing of the chloroplastic group II intron. Required for the accumulation of 16S and 23S ribosomes.
Subcellular Localization:
Plastid, chloroplast stroma.
Sequence:
MMKSLLFSVHPTPPLLPTPRLRRLLRFRASSSASASASAPPRADRRSPRPAPSRRPSSSSLYARPSLLEMERERAARRADVDAFLTSLGVDPGELAGLELPVTVDVMRERAEFLGSLGLTREDLAAYPLALGCSVRKNMVPVLDYLGKLGVRRDALPDLLRRYPQVLHASVVVDLAPVVKYLQGMDVRPADVPRVLERYPELLGFKLEGTMSTSVAYLVGIGVGRRQIGSVITRFPEVLGMRVGKIIKPFVEHLEGIGLQRLAVARIIEKKPYVLGFGLEEKVKPNTEALMDFGVRKEALASIVMQYPDVLGLELRDKLVAQQSLFESSILVSREDFGRVVERMPQAISLGRAAVQKHVNFLTACGFMLSQVSKMVVACPQLLALNMDIMRMNFEYFKNEMERDLEELVEFPAFFTYGLESTVRPRHEMVSQKGFTCSLAWLLNCSDAKFDERMKYDTIGVEEMEREDSSDMNASMEEVESEEYEDSDYDDSDDEFVR
The following text describes a protein:
Function:
Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MEFTAVIVCGKGKALTPFSQARSTGIPKPLLPIANKPMVQYVLDWCLQANFSRIIVLFEKEDESSGVLEQTIKRYQEEKEKTNTNKNESHVSIDVIPYNCENNGLILYKLYELYSENKVSNNNFIILPCDLITNLPPQVIIEAYRNKNDSDLGLVIAYKNQLDIEDKKAKIFPQSYTIYSDTDENGNESPMFLDTYSQADIEFHQALSIRTQMCWRYPAATVSNKLLNSGIFLGSCSQIFSVFDEQKDKFTESYFEKRSLMKIVRDLARRSWKHALHQASVGFFIVPKQATFFRCNNLPVLMEANRYFMKKQAIAKSASQNTQAPNKQDKQSGAHVGNDSLVGENTELGEKTNVKRSVIGSNCKIGKKNKITGCLILDNVEIHDDVTLENCIIGHDVIIQGKCKLTNCNVESTNEVAHNTQAKNSNLLCLTLEGLVNEDDQYGDDSDDEEDSEEYDSTDDEDESEFEDEYTGNEDGLFAY
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MRAREIFSARRGPAWSGAEPRMDGQDAEAGAPADIVAHADLGVAPAGAGAPSSKFLRFYRAATARSRRASGRRGRASPRRGGAADSSVDEGATAVPSSRDAAEEESPRRKQPVRVPQTPAKLAAPALEADDSDGFVTARSTPLRSPRRQLTFSSPSKSPRKTRKQDVLLAQVPSFKLDPGFVPAAVPKGYRLPEDRNLTYFFDGFEGYIDQKKPIRAHKKSRNSMAIAPSVSRDEFRLLSGALNGFMHQTPRAVLTGHQQRLFPQYWFEVMQGFTLLFYGIGSKRRFLETLVFEYLSPKLALSGAPEGADVEGVPCVVINGFNPACNYRDCFQSIAAYMLPDELRHAETKYWHNHVHLQIQKMVEHWAAQPPQVQMVVLVHNLDGPMLRKDPFQQMLSSLARIRQIAIVASVDHIHAPLLWDSLRAQLYNFVFHDVTNYEPYAIEAAFQESVRLNRSELQAGSIDAARYVLASLTANSKRLFRLLLETVVANMQSAKRIKLTNSRRAGISFGVPFSAFYQACAAQFVASNEMSLRSMLREFVEHKMAHLAKDKAGQEIVYVNYSFGEMQKLLSDALSSV
The following text describes a protein:
Function:
May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MFSALKKLVGSEQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALWHRLQGKKFVEEYIPTQEIQVTSIHWNYKTTDDVVKVEVWDVVDKGKCKKRGDCLKTENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYVLRELPKVPTHVPVCVLGNYRDMGEHRVILPDDVRDFIEHLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYSIFLEMMEARSRGHASPLAANGQSPSSGSQSPVVPPSAVSTGSSSPSTPQPAPQLSLGVSSTCPSAPSPAPSLEATPSSVHPPAPAPAQRRSIISRLFGTSPAAEATISPPEPAPALEAPVRVQNVEDFVPEDGLDRSFLEDTTVPKDKKVGAKGPQQDSDSDDGEALGGNPMVAGFQDDVDIEDQPHGQSLLPSDPIPSKNISLSSEEEAEGLAGHPRVSPQQCSEPETKWSSTKASHPQKKGAPTRGITPWSDGLTTDGSQRPQEGKDKQVSSESDPEGPIAAQMLSFVMDDPDFESDESDTQKRVGRFPVREDLSDVTDEDTGPAQPPPPSKFPVPAFRLKNDSDLFGLGLEELGPKESSEEDKDSKLPSKEKKKKKKKSKEEEEKATKKKSKHKKSKDKEEGKEDGKKRRKPPRSKEQKAADELEAFLGGGAPGSRHPAGGDYEEL
The following text describes a protein:
Function:
Catalyzes the synthesis of IV-HSL (isovaleryl-homoserine lactone), a quorum-sensing (QS) autoinducer molecule which binds to BjaR1 transcriptional regulator to activate expression of QS-dependent genes. Is active with isovaleryl-CoA but cannot use isovaleryl-ACP as acyl donor.
Sequence:
MIHAISAVNRHLYEDVLEQHFRLRHDIFVEERHWETLRRPDGREVDSYDDEDTVYLLALEGRRVVGGHRLYPTTKPSMMSEVFPHLAAVRGCPSDPLIWEWSRYFVVRDRRDGALNLQLMAAVQEFCLDQGIAQVSAIMETWWLPRFHEAGFVVTPLGLPALVENAWTMAATVDIRRQTLDVLHDRIGMPSIVQQDGPRLDAVARANLCGLAAAQRKSA
The following text describes a protein:
Function:
Forms the helical nucleocapsid (NC) in a ratio of 1 N per 6 ribonucleotides, protecting the genome from nucleases. The nucleocapsid (NC) has a helical structure with either 12.35 or 11.64 N per turn, approximately 20 nm in diameter, with a hollow central cavity approximately 5 nm in diameter (By similarity). The encapsidated genomic RNA serves as template for transcription and replication; encapsidation by N is coupled to RNA synthesis (By similarity). Forms the encapsidation complex with the phosphoprotein protein P (By similarity). Before encapsidation, the newly synthesized free N protein, so-called N0, is chaperoned by P (By similarity). Participates, together with P, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place. N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response (By similarity).
Subcellular Localization:
Virion. Host cytoplasm. Host nucleus.
Domain:
Ncore is globular and carries regions required for N self-assembly and RNA-binding. Ntail is an intrinsically disordered monomeric domain in the C-terminus.
Sequence:
MATLLRSLALFKRNKDKPPITSGSGGAIRGIKHIIIVPIPGDSSITTRSRLLDRLVRLIGNPDVSGPKLTGALIGILSLFVESPGQLIQRITDDPDVSIRLLEVVQSDQSQSGLTFASRGTNMEDEADQYFSHDDPISSDQSRFGWFGNKEISDIEVQDPEGFNMILGTILAQIWVLLAKAVTAPDTAADSELRRWIKYTQQRRVVGEFRLERKWLDVVRNRIAEDLSLRRFMVALILDIKRTPGNKPRIAEMICDIDTYIVEAGLASFILTIKFGIETMYPALGLHEFAGELSTLESLMNLYQQMGETAPYMVILENSIQNKFSAGSYPLLWSYAMGVGVELENSMGGLNFGRSYFDPAYFRLGQEMVRRSAGKVSSTLASELGITAEDARLVSEIAMHTTEDKISRAVGPRQAQVSFLHGDQSENELPRLGGKEDRRVKQSRGEARESYRETGPSRASDARAAHLPTGTPLDIDTATESSQDPQDSRRSADALLRLQAMAGISEEQGSDTDTPIVYNDRNLLD
The following text describes a protein:
Function:
Functions as a downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Is involved in pollen tube growth regulation through its interaction with ARAC11/ROP1.
Miscellaneous:
MISCELLANEOUS: Over-expression of RIC5 in tobacco germinating pollen reduces pollen tube expansion elongation.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MTSPMKGLLKGLRYIARIFEDEKEPEMQIGIPTDVKHVAHIGWEGPSATTPSWMHDFKPTDQTKTETKGTSNKKPGSSGEKHRKGRRKTSTGNNSPTESPSRVGGSVRPSKRNTGKQREQNTGSGSESGSGLELPQQTDQFVVPKQSKQKKSKGSATGGGEPPPSNEPSNKKETDISVRAVYPCAGLGSSTGR
The following text describes a protein:
Function:
Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
Sequence:
MADLKSTFLRVYSVLKQELLEDPAFEWTPDSRQWVERMLDYNVPGGKLNRGLSVVDSYKLLKDGRELTEEEIFLASALGWCIEWLQAYFLVLDDIMDSSHTRRGQPCWFRVPKVGLIATNDGILLRNHIPRILKKHFRGKAYYVDLLDLFNEVEFQTASGQMIDLITTLEGEKDLSKYTLSLHRRIVQYKTAYYSFYLPVACALLMAGENLDNHIAVKDILVQMGIYFQVQDDYLDCFGDPKTIGKIGTDIEDFKCSWLVVKALEHCDEEQKKVLYEHYGKADPASVAKVKVLYNELNLQGVFMEYENESYEILVTSIEAHPSKSVQAVLKSFLAKIYKRQK
The following text describes a protein:
Function:
Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MRLSPVLLRLSRGPALLALALPLAVALAFSDETLDKVPKSEGYCSRILRVQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGTGTRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC
The following text describes a protein:
Function:
Transcriptional regulator which can act as an activator or a repressor.
Subcellular Localization:
Nucleus.
Sequence:
MADRDSGSEQGGAAMSSGGSSLHPASGAGGSVLQHETQELASKRVDIQNKRFYLDVKQNAKGRFLKIAEVGAGGNKSRLTLSMSVAVEFRDYLGDFIEHYAQLGPSNPDMAQDEPRRALKSEFLVRENRKYYMDLKENQRGRFLRIRQTVNRGPGLGSTQGQTIALPAQGLIEFRDALAKLIDDYGVEEEPAELPEGTSLTVDNKRFFFDVGSNKYGVFMRVSEVKPTYRNSITVPYKVWGKFGHTFCKYAEEMKKIQEKQREKRASEHQQQEGHGDDGEDD
The following text describes a protein:
Function:
May be a regulator of keratinocyte proliferation or differentiation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAADLNPPEAFSLPKQPTNGTRDVPQLVPPSHFESPPVEDAWTQVRKLTRDVLDLRTENQQLRQARSAVIPAGEEIRARVDLHKSGNGETTRHLQGIIDKQINDIVHLKAELTALKAEHSREVQVLQLQVSAQDRQVEDAAVQARRRLEDAHRKHQDELHKIKVAHEEELRGAMSSLSGLQKQLEESRTDYEQRLAELEDQIYRSALEKEELQEKVRTTSDELQSSRSLVSQLKAHLKQMETDRQAAEQWKLERGERLKRIKDLEQQVENLQSTEQLLNMRLTSFTDILSIQEADITKSKSDGSDMNKRMNSLLTRWREKVYALMVQLMSQEIVHKKDIANYKQKIADLEDQLNSSTSHSEVLSHMLADRTAELEMEKTRVKTLQAEVTSAQDTAVSLQDKMDAQLAANGQLCDLTKRTFEAFAAQEDKLQAGGSKLTSFSQRLNFAVGRLDMLQGLFARREAMWRMKLEESTNQIKEEEDQPEKEHDGMLPSQLHEELDRVRRERDQLAAQMREDSQLLDQRMAANKHKFEGQLKDQQETIVQLHKLMEEKSQKCQSLGAQLSQLEDNIQEANHTIDGLKTELAKQQIEAEKAVEDRGREVQTGMVDQLAEMEKRMNDARREHTKAVVQLRQAERQTSREKERGQQQLQLQEQHYQRQLHKLQEQLREVDRDRNMVMATLRQEGLIGQYKQHRAAAAKAVSNTQPQGSELTTGSGTADKQQPIVAEPLSSVVEDLRSLTATVLGDEGDTDSSED
The following text describes a protein:
Function:
Regulatory component of the NEM1-SPO7 complex which acts as a phosphatase and dephosphorylates the phosphatidic acid phosphohydrolase PAH1. Essential for the formation of a spherical nucleus and meiotic division. The NEM1-SPOo7 protein phosphatase is required for efficient mitophagy under prolonged respiration, as well as for reticulophagy and pexophagy.
Miscellaneous:
MISCELLANEOUS: Present with 861 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Sequence:
MEPESIGDVGNHAQDDSASIVSGPRRRSTSKTSSAKNIRNSSNISPASMIFRNLLILEDDLRRQAHEQKILKWQFTLFLASMAGVGAFTFYELYFTSDYVKGLHRVILQFTLSFISITVVLFHISGQYRRTIVIPRRFFTSTNKGIRQFNVKLVKVQSTWDEKYTDSVRFVSRTIAYCNIYCLKKFLWLKDDNAIVKFWKSVTIQSQPRIGAVDVKLVLNPRAFSAEIREGWEIYRDEFWAREGARRRKQAHELRPKSE
The following text describes a protein:
Function:
Reductase component of a two-component system that catalyzes the first step in the aerobic styrene degradation pathway by enantioselective epoxidation of the vinyl side chain. Utilizes NADH to reduce FAD, which is then transferred to the styrene monooxygenase StyA.
Sequence:
MTLKKDVAVDIDSTCFRQAVALFATGIAVLSAETEEGEVHGMTVNSFTSISLDPPTVMVSLKSGRMHELLTRGGRFGVSLLGESQKVFSAFFSKRVMDDTPSPAFTIQAGLPTLRDAMAWFECEVESTVQVHDHTLFIARVSACGTPEANAPQPLLFFASRYHGKPLPLN
The following text describes a protein:
Function:
Involved in stress response.
Subcellular Localization:
Cytoplasm.
Sequence:
MDNYKKILVALALDPNSDRPLVEKAKELSANRDAQLYLIHAVEHLSSYGAAYGVAAGVDVEDMLLEEAKKRMNEIASQLNISSDHQIVKVGPAKFLILEQAKNWGVDLIIVGSHGRHGIQLLLGSTSNAVLHGAKCDVLAVRIKGS
The following text describes a protein:
Function:
Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKSVYPMSSPSSAVFADQGLSGKANQTQPPPPLGLVVPASKPGAKKPLRKNAWQVAPNLLVSFRYAWAGVSYAFATQRNFRIHTFTGVAVITAASLLHLEAIAVAVLALTSCLVMILELLNTALESVVDLTVGQSYHELAKIAKDCAAGAVLLAAIAAVIVGGCLLLPPLLSLMV
The following text describes a protein:
Function:
Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
Subcellular Localization:
Nucleus.
Sequence:
MFCCISNCVPHEPVVSRSSGCLYERSLIEKYIAEHGCCPITGEALHKEDLIAVRRTPLTGATFVADETVPALLAKLHSQWDAIMLEQFALRQQLTQTQQELAQALHQYEAACRVIATFLSDGKAEEDTRVVEQTESGAGDGSSEGNRVDEERIVLPGEVVRELEEHDSAQRQRRRTRSMPTTLATLQCVQGFTERNSVHLGRGACGVSRLVCGNVFVGLDNAAIIRCDVRGGQVQTAGVGHEGAVRHVVAMSGSCGDGNTSNGTLRVISGSDDASLRFWASEGEVLVCQGVVRHHKGGIVGLRSLTSGRLFLSASSTEVGLVDAVRLDSVVCVNGATMGFSRIISLDAHPYGALAAIGVEGAGFCIWSTAYMCVDTTVSLKGKGDVCSIAFNGDCFTLATGLRDGKALLWDLRNLSTPFREILPEATALKGSALSGAVCTVAFDDYGKYLAVGGCHTRLYDWAAPSEGQQELCTLNTGPQSVAGILWDVDAQGLVSCSVDGVVKEYRST
The following text describes a protein:
Function:
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MQGKIFILPKDSTNQQFVELSHPLTGRPLRYLLTNDHLLQILQVGDSSKQRSWFVGDHVVSDGYLYVCTPIDLLALVLPIIQELTWSRRKEPNRYVSFEDFIEHFDNMGPHYPRVSEVLSPNLLNTLHRICKVNEPVGSLPKTFQLDESSVVKILLRKAKVAQENLPPSIVTELKKQLAPLDLRTPLPQDLLELSCKWHAASLVCEDLQPEWYNKLAYWQEELAPLHAYTKNLEESRKILVEKEALLNSKKRPQNSDITSSLLKKPNRKQATKKSKYFSGEGMTKISSFFTKK