lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Peptide hormone that functions as endogenous ligand for the G-protein-coupled apelin receptor (APLNR/APJ), that plays a role in the regulation of normal cardiovascular function and fluid homeostasis. Functions as a balanced agonist activating both G(i) protein pathway and beta-arrestin pathway of APLNR. Downstream G proteins activation, apelin can inhibit cAMP production and activate key intracellular effectors such as ERKs. On the other hand, APLNR activation induces beta-arrestin recruitment to the membrane leading to desensitization and internalization of the receptor (By similarity). Required for mesendodermal differentiation, blood vessels formation and heart morphogenesis during early development and for adult cardiovascular homeostasis. Acts as a motogen by promoting mesendodermal cell migration during gastrulation by binding and activating APLNR (By similarity). Acts as an early embryonic regulator of cellular movement with a role in migration and development of cardiac progenitor cells. May act as a chemoattractant for the activation of angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis (By similarity). Positively regulates sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel sprouting. Plays a role in placental vascular development; promotes placental trophoblast invasion and spiral artery remodeling in the uterus. Involved in the regulation of maternal cardiovascular homeostasis to prevent gestational hypertension and for potent cardioprotective functions during heart failure. Mediates myocardial contractility in an ERK1/2-dependent manner (By similarity).
Subcellular Localization:
Secreted. Secreted, extracellular space. Note=Found in blood plasma (By similarity). Found in serum of pregnant mice, peaking at midgestation; indicating a maternal and zygotic origin of circulating APELA during pregnancy.
Sequence:
MRFQPLFWVFFIFAMSLLFISEQKPVNFPRRRKLYRHNCFRRRCIPLHSRVPFP
The following text describes a protein:
Function:
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
Subcellular Localization:
Cytoplasm.
Sequence:
MKKNFALIGPRGVGKSKISRKLSKITGMPVVSTDMIAVYEIGGMSIPEFIQKNEGDWRPFRNLEFEILTKLKTSQGIILDCGGGILFDLDTKGKEILSDRKTTLLKSIAVVFGLSRPTEILVEKIQNDPTRPPLSTIQSYRTILESRLPYYQSISDYYLEIDDLKVEEICSRILQKIEY
The following text describes a protein:
Function:
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
Domain:
Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
Sequence:
MSNKKDFIDRIHREVPIESYISRFIPLKKRGKNFIGLCPFHQEKSPSFNVSAEKQFYYCFGCKASGDLIRFVMSYERVDFSRSLEILSEYSGIPLEEKSSKNSEFSDFLYKINLKVSEYYQHLLHTPTGKNALDYLKSREIEDSEIRLFGLGYAPEGFDTLAKEVLKTKEEISGAIQLGLLREKEAGNGRPYDFFRDRIMFPVLDLSGRTVAFSGRILGPGKEAKYINSQASLIFDKSRTFYNFFKAREGVRKSGEAMLVEGYLDVIGLVRRGYENVIASMGTAITENHIRTLKKFAERVTFVLDGDIAGKKGALRAAEICLKEGMECSIVLLPEGKDPFDLSKSLSRPELHEILSDRIQGSEFVVEELLENADSRALPEKKRKSLQNLYSFIQTLGRETDKQFLLGLGANKLGISMDAVLRDFKGGTGAKNGPSNADTSSNLKEVQGISGPALDCERKIVSMLVKHTGLFSYSEEISSMEFMDIASSYLWDYLYTIYTGEEEISPVGILTSELPEDLKQILAPYLLEEDSEKTEPGELHKVFRILLLQQKKFRIEEKIRELDQKRERFFTPEIFTELSFYRKEKEKILEHIRSQSTT
The following text describes a protein:
Function:
Involved in ER to Golgi vesicle-mediated transport by either facilitating USO1-dependent and -independent tethering or increasing target accuracy of fusion events of COPII-coated vesicles.
Miscellaneous:
MISCELLANEOUS: Present with 5220 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Golgi apparatus, cis-Golgi network membrane; Peripheral membrane protein. Note=Localizes to cytoplasm in a punctate pattern. Localizes to cis-Golgi together with GRH1.
Sequence:
MSEQESDEVKRMKQLEEARKRVEELKKKKNKKNKGKKNKNSSATGSIGSETPDLEGTPGEESTQEETVKANSTKSENNDQNDVDEESEEKEIEQVKSDPSGTTEKDIEEINSTSSNVGKDDAENTKKEEVQEVIKNNNDEQTADAGKTIEPQEEKKIVQTQEGNEPSNTSEAADDLFANDGNEESDFLTTIKKQKEEDELTKLRAENEKLTQENKQLKFLNMENETTVDDLQDQLQEKEDIINGLQNDLQTARDELIAAVEKLKLAEAKAARNTTATPIQFADFNTSSNNLTPSQSVTNSGTQVAHGNNMEVDRVMLNKWRQWNVDMTTWRSIGSGPIMEF
The following text describes a protein:
Function:
Involved in succinate export with YjjP. Both proteins are required for export.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MGVSLLWALLQDMVLAAIPALGFAMVFNVPVRALRYCALLGAIGHGSRMLMIHFGMNIELASLVASIMIGINWSRWLLAHPKVFTVAAVIPMFPGISAYTAMISVVEISHLGYSEALMSTMVTNFLKASFIVGALSIGLSLPGLWLYRKRPGV
The following text describes a protein:
Function:
Converts proline to delta-1-pyrroline-5-carboxylate.
Sequence:
MSGAGCVNLEHNSRIVMHADASRTPLAMSWKSHGSTVKVRCRIYGSYLMSIEKNPVLSQILKKTFYAQFCVGEKKDEVVANTNFAREVLGYDGILFEYALEVLGGATPTPAETAQEIEVWRKGMLQSVEMAKEGDFVGLKWSGLGRHALHLLKTQQPATPEMWSAITAACDAAAAKGVSLLPGAEEEATNPGLEKWTLELQKKYNTFERGRAVVYITYQCYLRTINQRLAQHLEKASKEGYIAGVKLVRGAYLTSEPKELTFDSKEGTDKMYDAMAEAVVKQQWTDTVPAPSPDTPFPKVNIVLATHNLPSILAAKAVRASQLASQPAQSLPRLTYAQLQGMADEISQSLVQDSTMKADTQAKVVKCMTWGTTTECLNFLLRRAAENKEAAARTVDTRKAMGAELWRRFKGVVGLA
The following text describes a protein:
Function:
Required for full induction of the nrgAB operon under conditions of ammonium limitation.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MSGQMFKVEIVTRPANFEKLKQELGKIGVTSLTFSNVHGCGLQKAHTELYRGVKIESNVYERLKIEIVVSKVPVDQVTETAKRVLKTGSPGDGKIFVYEISNTINIRTGEEGPEAL
The following text describes a protein:
Function:
Component of the mitochondrial outer import machinery (MIM) complex that mediates transport of proteins into mitochondrial compartments. Promotes the insertion of tom70 into the outer mitochondrial membrane. Promotes the insertion of atg43 into the outer mitochondrial membrane. Involved in import of the subset of proteins with multiple alpha-helical transmembrane segments (By similarity).
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein.
Sequence:
MAEVLDLEIDPISDGEDDTYSSELDDDLKDSIEQLERVLCLVVFPLLGKFLGRKFAFHAWARWLERRRLVSN
The following text describes a protein:
Function:
Lysosomal proton-coupled steroid conjugate and bile acid transporter. Preferentially recognizes lipophilic steroid conjugates or bile acis as endogenous substrates and seems to mediate escape from lysosomes to the cytoplasm. Modulates hepatic cytosolic copper homeostasis, maybe acting as a lysosomal copper transporter and sequestering copper ions in the lysosome (By similarity). Transports catabolites of non-cleavable antibody-drug conjugates from the lysosome to the cytoplasm. Delivers pathogen-associated molecular patterns to cytosolic pattern recognition receptors as part of the innate immune response to microbes. Selectively transports bacterial muramyl dipeptide (MDP) into the cytosol for recognition by NOD2, triggering inflammatory responses (By similarity). Likely acts as a redundant importer of cyclic GMP-AMP dinucleotides (cGAMPs) in monocyte and macrophage cell lineages. The transport mechanism, its electrogenicity and stoichiometry remain to be elucidated (Probable).
Subcellular Localization:
Lysosome membrane; Multi-pass membrane protein.
Sequence:
MKILFVEPAIFLSAFAMTLTGPLTTQYVYRRIWEETGNYTFSSDSNISECEKNKSSPIFAFQEEVQKKVSRFNLQMDISGLIPGLVSTFILLSISDHYGRKFPMILSSVGALATSVWLCLLCYFAFPFQLLIASTFIGAFCGNYTTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTGLSSGYFIRELGFEWSFLIIAVSLAVNLIYILFFLGDPVKECSSQNVTMSCSEGFKNLFYRTYMLFKNASGKRRFLLCLLLFTVITYFFVVIGIAPIFILYELDSPLCWNEVFIGYGSALGSASFLTSFLGIWLFSYCMEDIHMAFIGIFTTMTGMAMTAFASTTLMMFLARVPFLFTIVPFSVLRSMLSKVVRSTEQGTLFACIAFLETLGGVTAVSTFNGIYSATVAWYPGFTFLLSAGLLLLPAISLCVVKCTSWNEGSYELLIQEESSEDASDR
The following text describes a protein:
Function:
Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine.
Sequence:
MPFIHRRHFRDDEDICISPMYRVPGRHLYYALSVYGGAGGWGTRISTGPTPFQYGKEVGMGRLLLGNEKLAMQNLNDRLANYLEKVHSLQQANFKLEAQIRQWYQKNSTPVDEDFSSYHQMIEELQNQIQNAQKNKVQWILKIDDVKLKEENLRIKFDNERAMCLSVEGDIQKWTKAIDDLTLMKARLEMQVENLLKERVVLKKNYQEEANNLRKHLGATINVKLDAAPGPDLGAIINEMREKYEKLAEKNIKEAKWRLEKLMIELEKQVVDNDKELEVNMIKLKELRHKRQNLGIELQSQLCQKKSLEAILGRPKTHCEPELALIQEKLSIFKAQLIQIRSESERQKDEFKILLDIKIRLEKEITTYRSLLERGAVGQGSRKLSRLSHSKKIRKIRMVVEEMVGGKVVSSESKEMEEILKREQKIPFRTPIENRGFLKL
The following text describes a protein:
Function:
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MKLTTVQIPAIAKHTATVVFLHGLGDSGYGWQPVGEMLAPRLPHIKWIFPNAPNIPVTLNGGAVMPAWYDITSLNGNGREDKPGLLASAKTIHELIATEADLGIPTNRILLGGFSQGAVISLLASLTSESKYAGVVALSGYLALRNEISELKKTINDTTPFFMAHGHEDEVVKYEYGKLSSEYLKNQLKLNVDFKTYHGMGHSTHPKELEELELFIKQVLDPTATGSNK
The following text describes a protein:
Function:
Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
Sequence:
MYRAAAKIASNARIAGVLGQQIGGKFGYARNYAAKDIRFGVDARALMLKGVEELADAVKVTMGPKGRNVVLEQSFGAPKVTKDGVTVAKSIEFKDRVKNMGASLVKQVANATNDVAGDGTTCATVLTRAIFSEGCKSVAAGMNAMDLRRGITMAVDNVVTTLKSRARMISTSEEIAQVGTISANGEREIGELIAKAMEKVGKDGVITIADGKTLYNELEVVEGMKLDRGYISPYFITNQKNQKCELENPLILIHEKKISNIQALVKVLEMALKIQRPLLIIAEDVESDILATLILNKLRAGIKVCAIKAPGFGENRKANMQDLATLTGGEVITEELGMNLDKVEFEMLGTCKKVTISKDDSVVLDGAGDRKAIEERCEELRSAIEASDSDYDREKVQKRLGKLSGGVAVLKIGGASEAEVGEKKDRVTDALNATKAAVEEGIVPGGGVALLYASKELDKLHVANFDQKIGVQIIQNALKTPVHTIASNAGVEGAVVVGKLLESDNYDLGYDAAKDEYVDMVKAGIIDPLKVIRTALVDSASVSSLMTTTEAVVTELPKDEKDASPMPGGMGGMDY
The following text describes a protein:
Function:
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors.
Subcellular Localization:
Cytoplasm. Nucleus.
Domain:
Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
Sequence:
MTSVIARSTGSTLHHIKRCWSGSLIGGKQCIRPSALPQSVVRNGSVPVCPFGTKFSVMGKPKVVFVLGPPGSGKGTQCEKIVKEFGYTHLSAGDLLREERNREGSEYGALIEDNIKNGRIVPVEITCALLENAMNKTTEATGNDRFLIDGFPRNEDNLQGWTKKMADKVEQQFVLFFECSEQQCTERCLKRGESSGRSDDNAESLKKRFNTYINDTVAIIKHYEELQLVKKIDASAGPDAVFEHVKAIFGEQK
The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MASALDRALNNFRAQPRDMSGQKKAKVSLIFEPTVAASTSAGTFYQVGYAGYTELLQIDHRIKKFEKSIFNPSITDVDPLFLTAEEYNPLREKVRELMFFLSNYCMEVSAVKVLEYLIQQFAVNRLNPEILLFITLPYLETPLFVRVIQTIPFKAMPKAFDFLDDFRHISQTKKPIDRKLLISWIIKKPNILPWIISNVPRVCAYHPDGVYASFVGVLFSQLIMENIDEAMGTNIINAAMAALDDPNGYLAPQYLMAVLTLNEKKELGILPKITKKISSNAETVFANHFSEMFSLTVALFQKSVPIHVKEGFVHAIASQISSVKDLIRNTDTTVIAKSCSNLIVKKSKNESLVKSAIAILETNFFETVAKEFLLGFVQNYPGGEYAEMLVQKLANDYPEILTEDVNSALKSANISVRLSAHTRQSIIDSLSESSKAAAVFADPDLQFDLASNQAVSCLTSAESADSVEVVEPLIKYFKGRCPEHVLQWICEHLFISGSKFSDCLIKNISVYGKELADFLEGFPTDSNKSILSFLSAKSKELPNFKSLPIAAAKALNEKSSEKVTDLIKFLPQRKLDYSVVRSLETKIFQEDLEFVADSMESQAAFILAVTHKIAEESELTTDNLLALFSFPDFRCLLPTVVLLATKKQLNKMTSVFHISNQQENNAKINCLTLIAVVLPMSNPYDIIPTLFCALKSPVYKDRAMELIRGISLKEEGIKDVLPYVIKHHQLFGNDEQTTIGVFTKSCAKPETRTFYNHCWEHIQDCSIALDFFLLTNDKECFSAIKRLEKEPKIVDLFDNYIQKYPDNEEAKDWALNTLNSGVIKSVIPYLNETKLSKSLPFVCSYPQYYATSFNLFFKNHNIPYKDIEKEITKGQTSAIKESKTEIPPQIFANKNFNGLLKSLQARIVVSPCQILLENISNKQEVDGIVELVPSIISLFDMKENSNLIPYIFNCLLMAIKKENETTEKKKKSCTDIMIENFSKIISSISSTTVPHIHSTALQVVEELARVKPEEVAKHAKTFFSAMPTETLFSDDVANLARINQLLSSVLPILEKANTIMELLNFFSENIDRFSMDRASKIMIHSIGCLNSESYRVFDSLLKHDKVDFALTLTDQMKAETLMSSIIRLTELTEKSDNFKDFISQIQFPSLPVPMIRFFMVLQKKFDEDEFRDIVTDVCNSWGLPDFISFSEEAVVKPTMTTLVQSLITQRISNEPSPLFSSLLKPLQSLIEHGTELQLTLNTLQGITQLLEEEHAPIVSTLITKTLDAINQETIKPSIQLAALSFTANAVEKFKMSILDVYPPVLDFAAEFLQMVVEHEAADAIGPTVGSVCLLLSASPEFSADKLVKIVPSLLSPMILNREELSTLVNKNLTEIVAVLSLDQVLPSFVATLEVKNASPESLIGMFDLMTKSLKHSDVHMVRRLQATLLKFFLLSFTIRFDDIDDNMMFQDAVAETFGEYANRLNEQLFAIAFSTILQYMLTLSDKKQKDYVVGRFFFARVIHSIVNTLREVFAKFYSSFFDSFIQFVLESDDGILEQREVTIRVMFVLTKICDYADQIFFETRFSKVLDAIKMHFNCFEGELTTETMESESDRERTYEYKMFVLGNAFAALMNASKTNLTQMMNVLIEQLRNEKSIIVINILNVLLICSENARDNFSSVFTSALPVINELLEHPDADIQAAARNAVHSLARTNESVRNFFISDQ
The following text describes a protein:
Function:
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Subcellular Localization:
Nucleus. Note=Colocalizes with COIL in subnuclear Cajal and histone locus bodies. Translocates in the LEC complex to Cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes.
Sequence:
MSSKMVISEPGLNWDISPKNGLKTFFSRENYKDHSMAPSLKELRVLSNRRIGENLNASASSVENEPAVSSATQAKEKVKTTIGMVLLPKPRVPYPRFSRFSQREQRSYVDLLVKYAKIPANSKAVGINKNDYLQYLDMKKHVNEEVTEFLKFLQNSAKKCAQDYNMLSDDARLFTEKILRACIEQVKKYSEFYTLHEVTSLMGFFPFRVEMGLKLEKTLLALGSVKYVKTVFPSMPIKLQLSKDDIATIETSEQTAEAMHYDISKDPNAEKLVSRYHPQIALTSQSLFTLLNNHGPTYKEQWEIPVCIQVIPVAGSKPVKVIYINSPLPQKKMTMRERNQIFHEVPLKFMMSKNTSVPVSAVFMDKPEEFISEMDMSCEVNECRKIESLENLYLDFDDDVTELETFGVTTTKVSKSPSPASTSTVPNMTDAPTAPKAGTTTVAPSAPDISANSRSLSQILMEQLQKEKQLVTGMDGGPEECKNKDDQGFESCEKVSNSDKPLIQDSDLKTSDALQLENSQEIETSNKNDMTIDILHADGERPNVLENLDNSKEKTVGSEAAKTEDTVLCSSDTDEECLIIDTECKNNSDGKTAVVGSNLSSRPASPNSSSGQASVGNQTNTACSPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKVPELPLMNLENSKQPSVSEQLSGPSDSSSWPKSGWPSAFQKPKGRLPYELQDYVEDTSEYLAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISNLFNILQHILKKLSSLQEGSYLLSHAAEDSSLLIYKASDGKVTRTAYNLYKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLDTTTQQKIGGTRMPTRSHRNPVSMETKSSCLPAQQVETEGVAPHKRKIT
The following text describes a protein:
Function:
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
Sequence:
MNAPRPKKNCKLRPSPALPLVSHRIRGFFNGFCVTLDDPDDMKTVISMGYFGKANLSRNYPHFGVKQPEIVFKRVYENRKRHANDKPRKIVVLSDDLDDLTNFRPEFRLDSSGLRESVNLGLEEAFFLATAINCLDVYDEVCLSPEQLWEVFKKSDKYFAQNYIAYYYFRAKNWVVKPGIKFGGDFLLYKQGPPFYHASYVVIICVVDGDLKPIKSQNRRSMRKTHLMGLNRLCETARKELLICEIVCPGVSPDSIPFNEIGKFTIKETIMKRWTPQMDQN
The following text describes a protein:
Function:
Effector protein involved in the induction of tumors in infected plant tissues by the fungus. Required for the reactivation of plant DNA synthesis, which is crucial for tumor progression in leaf cells. Interferes with the MAPK-triggered phosphorylation of maize SGT1 at a monocot-specific phosphorylation site, resulting in both modulation of immune responses and reactivation of DNA synthesis during leaf tumor formation.
Subcellular Localization:
Secreted. Host cytoplasm. Host nucleus.
Sequence:
MLFTTFVSLLLVILCLVHVSAHPLQSFRSSSAIGKQKHKIKSRQFEEEIAQGAEDSIELFEFPRVHDSSEQIHERTEQQNITTKNIILAINKNSRKHGGLHRLPAQVQGEGEFTYDRQRNAVGSYRYGDSHGNSREAEYSVADHQSASGEYKFGPTT
The following text describes a protein:
Function:
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Subcellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis (By similarity).
Sequence:
MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQIPEASARLTQTLTIERRGVEIEEGGIKVKLTVVDTPGFGDSVDCSDCWLPVVRFIEEQFEQYLRDESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPKETQALKQKIREQLKEEEINIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGPRPVRGRHYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQLSQAQGEQSDAL
The following text describes a protein:
Function:
Harbors a corrinoid prosthetic group and acts as a methyl group carrier in methanogenesis from methylated-thiols.
Sequence:
MIRHIDLAVQNILEMKEKEPAKFKRLIDEGIMIGLGVDLEDGNKEVTTVDQIKNQNRPKDPEYASVAEAVIEGNNAETVKLISALLEKGKDPTDLVLNALMPGIQTVCELYDIGESYVPEILLANEALMKGVELCQKKKGEVPSQGKVVSLVIVGDLHDIGKNIVAAILRANGFEVIDLGRDVTVEAAVEAVKSTKANLVTGTTLMSTTKGGLKALANALEPEGVPLACGGAAVDRRFVDTFGNSVYGRTPLDAVKIAKEICEGKSWEEARNELY
The following text describes a protein:
Function:
Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate. Displays broad substrate specificity since it is able to catalyze the oxidation of a number of alternative aldose sugars, such as D-xylose, D-galactose, and D-fucose, to the corresponding glyconate. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a preference for NADP(+). Physiologically, seems to be involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
Miscellaneous:
MISCELLANEOUS: The reaction follows an ordered Bi-Bi kinetic mechanism, involving an ordered binding of NADP(+) and D-glucose, followed by an ordered released of gluconolactone and NADPH.
Sequence:
MKAIAVKRGEDRPVVIEKPRPEPESGEALVRTLRVGVDGTDHEVIAGGHGGFPEGEDHLVLGHEAVGVVVDPNDTELEEGDIVVPTVRRPPASGTNEYFERDQPDMAPDGMYFERGIVGAHGYMSEFFTSPEKYLVRIPRSQAELGFLIEPISITEKALEHAYASRSAFDWDPSSAFVLGNGSLGLLTLAMLKVDDKGYENLYCLGRRDRPDPTIDIIEELDATYVDSRQTPVEDVPDVYEQMDFIYEATGFPKHAIQSVQALAPNGVGALLGVPSDWAFEVDAGAFHREMVLHNKALVGSVNSHVEHFEAATVTFTKLPKWFLEDLVTGVHPLSEFEAAFDDDDTTIKTAIEFSTV
The following text describes a protein:
Function:
Does not function as an inhibitor of trypsin, chymotrypsin, subtilisin or elastase. Binds sperm and enhances sperm motility. May act as a decapacitation factor, suppresses BSA-stimulated sperm capacitation and blocks sperm-oocyte interactions in vitro.
Subcellular Localization:
Secreted.
Sequence:
MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LevDE PTS system is involved in fructose transport; LevD and LevE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator.
Subcellular Localization:
Cytoplasm.
Domain:
The EIIA type-4 domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the EIIB type-4 domain.
Sequence:
MISVIISGHGDFPIALKESSGMIFGEENNLIAVPFFKGEGIQTLQEKYHQALKDIPEEHEVLFLVDIFGGTPYNAAASFIAEDQRMDMAAGVNLPILLEVLSLREHLALKDLLNNLKAMSQQSFQVCSEHLEKVKTANQDTREDEL
The following text describes a protein:
Function:
Involved in the breakdown of putrescine via hydrolysis of the gamma-glutamyl linkage of gamma-glutamyl-gamma-aminobutyrate.
Sequence:
MTRKPLIGLNADFRAAARSTPAFAYIASGYYQAIINAGGIPVLVPPQADEESVSRVLDAVEGFLFIGGGDLDPRNDGFMLHPSVHPMDAARETSDRMLMAEIAERRMPVFGIGVGMQLINVQQGGNLFLHIKEDLPEAVPHFDAQDVNHRHTLNVESDSLIGRVYGDGEIRVTSRHHMAIDEVAPGFRVTARCPDGVIEAIESEMIDWFALGTQFHPESEAASALDIRIFEEFVDAVRDRNQDAPAKEGDEAYRLVA
The following text describes a protein:
Function:
Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms.
Sequence:
MRAVVLALSLALVGATVFPEFSAGKTYVYMYEMSVINGLPEEGLARAKMNASCKFLISAFDKNTYMLKVEDVMMQEFTGFWPKEHAESIGNIPKAFTPEFNIPIKFEYSNGVVGKVYAPEGVSDLVLNFYRAVLNIIQLNIKKTHNVYDLQETGIQGVCKTLYSVNEDVKAERIHLTKTRDMNHCQERVYRDMGLAYTEKCDKCQQESKNLRGSTSYRYTLKPVLSGVMILEADVNELIQFSPFSESYGAAQTETKQTFVFQEIQDSSIAPISAEYHHRGSLKYEFTNDFEWTPLQLVNVTDEQAQVLKELLNHLVTHNAEKVTDHAPLKYLELVEFLRLARYEDLEAFWSKYRDTLWLLEAIPATGTSAALRFIKEKFTSEDLSVTEAVRTLVAAVHMVTANPESIKLFETLTEDSKLNANPVLREIVFLGYGTMISKYCAESDVCPVEYIKPIQKRLSEAVSKGETEDIILYVKVLGNAGHPSSLKSITKIMPIHGTAAASLPITVHIEAIMALRNIAKKEPRMVQELALQLYMDKALDPELRMLSCIVLFETNPSMALISTLANAVKSEENLQVASFTYSHMKSLSRSASMIHPSVAAACNVAMKILSPKLDRLSLRYSKAVYGEAYSSSFMLGAAATAFYINDAATFLPRSVVAKTKAFFVGAAADVLEIGVRTDGLQETLLKNPSVLKSGDRITKMKRVIKALSQWRSLPNNKPLASFYIKLFGQEIAFANIDKPMVEQAIAAFGVKALKTLLLSGVSFNYTMPVMYTEMRRAIPTATGISVQLSLFSAAVAGAVVKIEPTLLPHLPEDFPLSRLLETDIKLETEIRPSFAMDTYAVMGINNPFYHAIIVSRAKFNSTLPSKISARLDIKEGDFKIEFINFAVHEEKMMVNRKKFRNQSEHTFWQEESSDVFFGRNVNRERNHGRGQGRGRGKGNFKGNYRRRFRGSSNRGSEQVDDGCWICRQRDHWEKEIVLKGRNQID
The following text describes a protein:
Function:
Phytotoxin which causes production of phytoalexin in platanus acerifolia, platanus occidentalis and platanus orientalis. Induces cell necrosis in tobacco leaves, and in callus cells and leaves of P.acerifolia. Induces reactive oxygen species (ROS) synthesis, nitric oxide (NO) production and mitogen-activated protein kinases (MAPKs) phosphorylation in the leaves of A.thaliana and P.acerifolia. Results in H(2)O(2) production on the epidermis around the stomata, rapid closure of the stomata, reduced photosynthetic and CO(2) assimilation rate, and an increase in a number of volatile organic compound (VOC) emission in A.thaliana leaves. Induces overexpression of genes related to salicylic acid- and ethylene-signaling, camalexin synthesis, ROS production and oxidative stress, and genes of various receptor kinases, and down-regulation of a number of jasmonic acid (JA)-signaling genes in A.thaliana leaves. Renders resistance against C.platani in A.thaliana and P.acerifolia. Renders localised resistance of A.thaliana against infection by virulent foliar pathogens B.cinerea and P.syringae pv. tomato. Binds cellulose analog carboxymethyl cellulose (CMC). Expansin-like protein with probable fungal and plant cell wall loosening activity based on its non-enzymatic cellulose weakening activity in vitro. Increases glucose production by cellulase after pre-incubation of cellulose with this protein. In contrast, according to PubMed:23512479, no synergistic effect with cellulases. May have a structural role in the fungal cell wall based on its ability to bind chitin, but does not bind beta-1,3-glucan.
Subcellular Localization:
Secreted. Secreted, cell wall. Note=Localizes on the cell walls of hyphae and conidia. Localizes on the cell walls of ascospores. More abundant on the conidial and ascospore walls than on the hyphal wall. Distributes across the entire thickness of the conidial wall. More densely localized on the layer near the plasma membrane than on the more outward layer of the ascospore wall. Also localizes on the fibrillar material at the surface of ascospores.
Sequence:
MKFSILPMIASAMAVSISYDPIYAADLSMGSVACSNGDHGLMAQYPTLGEVPGFPNVGGIPDIAGWDSPSCGTCWKVTIPNGNSIFIRGVDSGRGGFNVNPTAFTKLVGSTEAGRVDNVNYVQVDLSNCINGAN
The following text describes a protein:
Function:
Involved in the latter stages of lignin biosynthesis. Catalyzes one of the last steps of monolignol biosynthesis, the conversion of cinnamoyl-CoAs into their corresponding cinnamaldehydes. Probably involved in the formation of lignin in defense responses.
Subcellular Localization:
Cytoplasm.
Sequence:
MSSNFEANNNNNGEKQLVCVTGAGGFIGSWVVKELLIRGYHVRGTARDPADSKNAHLLELEGADERLSLCRADVLDAASLRAAFSGCHGVFHVASPVSNDPDLVPVAVEGTRNVINAAADMGVRRVVFTSSYGAVHMNPNRSPDAVLDETCWSDYEFCKQTDNLYCCAKMMAEMTATEEAAKRGLELAVVVPSMTMGPMLQQTLNFSTNHVARYLMGTKKSYPNAVAAYVDVRDVARAHVLVYERPEARGRYLCIGTVLHRAELLRMLRELFPRYPATAKCEDDGKPMAKPYKFSNQRLKDLGLEFTPLRKSLNEAVLCMQQKGHLPLIYPVPKRAYL