lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity. Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C.
Subcellular Localization:
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MIPPSGAREDGVDGLPKETASAEQPPSPASTGSQESKLQKLKRSLSFKTKSLRSKSADNFFQRTNSDVKLQADVLAGVSPGSSPLPAPGSLTCTPTRAGLYPGGGGKAHAFQEHIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCMDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKSSSGSGSDSPHRTSTSDLVEVPEEADGPGDGYDLRKRSNSVFTYPENGTDDFRDQAKNINHQGPLSKDPLQMNTYVALYKFVPQENEDLEMRPGDMITLLEDSNEDWWKGKIQDRIGFFPANFVQRVHQNEKIFRCVRTFSGCKEQGQITLKENQICVASEEEQDGFIRVLSGKKRGLVPLDVLENI
The following text describes a protein:
Function:
Negative regulator of epidermal growth factor receptor (EGFR) signaling.
Sequence:
MDIVGLGATMDIDILPLVLAPLPVITWREDTSALAQFYWADQELNLVATELDSFDGRKDPDRCSALVNQLRVCQDRVLGICHEIMDEAIPDSRADRDFRAKFPDDVLQENMSGLLWFGAECLAAGSNIMNREIESSQMRPLARALTRSLDNVRCLLREQCLRNPHEYPGKVKESLKTFDRLFAEFELSVCNVKILMKHARRSTEEADIDRLHPVAIKVKLVPQEMVDTYDPALMFTIPRLAIVAGLLLFPDGPLNVDRDLSRLSELYRPFFSLLCKIRELLWTLSREELWLLEKTLCQLEEPKTSLTNEQTSLGTDDYAVLDSDIYINLFYRNHQNCKQFIEDFYNHNFAAASDSETILPLQKGKGSPLLRKCTLSEKTLLSPLHKASSDDDSSNYDSDDSALSESWWPLLNDVLQAGAPREAARSSEQSAIHSRLRRTSGLSTASDRAPVVPQVRRLQSEQGGSSLGSPCSSCKSLSSLSISDFESMSYQSTDTSSYNSECHDDEEIALALQAVEIAFRNEARSRFKSSEDLIHRLFVCISGVADQLQTNFASEMRNILKCVFEMNSSVRQESPSSAVEAESPTERSSLSESSVFSLPFLDIVEMEDSGVRLGSGRRSVDSAEEAMPDDLSLDLSPESGARSPPVWLPDELTASCMDCSAHFTLLRRRHHCRKCGKIFCSRCSSHSISLPHYGHSKPVRVCNACFICHVTSVVEEIVNSC
The following text describes a protein:
Function:
Probable protein phosphatase.
Sequence:
MNNEQLQSTSSSPSTLLKPIEKKSRFLRLYSSDGQRSTRIECDEHTTCAQICQQFSCDVITLQIGNYHFRQLKSDTSPLAILQDFCRILTMSDENLETESTSKALEDILSYTDSPAFRHIFSFFLGRPRIRAKSTLNLDILSEEVVIRKGKLIHTWQNARAVFYNSNIRLQTKNNQDEALQIRNMKVDVHESKRGRALRLKDDDVCYLIIFQRPNILEAWLTRAQQVEKSNHVDASDEQLTLIPEQILNNEARVQILNLRRNSLISRPPTEKSMAPLGYIDDLYRVHSLQVIDLSANQILSFPIQLTLLSHLRQLNLSSNYISSVPSECSNMRRLQYLNLSNNQLDTLPDSISELQNLQSLDISFNQFSQIPPCLFHLTLEMWRLAGNNIEKIDRVGEMQIQKIDLRRNVLDTSFRLDIENITHLDLRDNSMISTVHLTNLRFLKVIHCERLQLSSLHLSGESLTHVYADHNLLDSLVVMPLPQNLQTLSLSFNHFRNLPDWISDCPNLTFLRANNNSLVALPERIFYSQSLRSIFAFINEIEHIPDFGEENCLETLILYKNKLSSLPKHFFSILPRLRQLNISSNFIELLPYFDGSSFCRLQILRCANNYLTENSVPVIVNMKHLKIIDLSHNRLNSFDDSALSSLELLEDLNLSSNRLTRLADCLALLPCLQVLRAHSNQLVHVPEFRASNQLHTIDVSSNNISLGTLQFKAPPNLRHFDVTCNSGDFDTENFPENAKMHSKMNTINISEGSQNLFGFQIGVSGSRGMKNKQCIRQVRVENTFGFIDGGSNSYMSSSICRFMTSYLKENVSMDIRSILLRCHCELGEEGERLGASVMIIRVHEKRLEIASTGTMSAAIARNQKLKMIINGRYEIDDDEYSRIREAHGFVDEENRINGVIGSSRQIGHFSTFPVVLPTHSYRNIQLNEQIEGLIVGNNMIWNMLSIDDLNSTFHNNRSPIVVAKKIQDQLQSYDYGGNSNILVLRRIKPQMTFNGFSTSSTKNQVTPDIAIPKIDEQLVLAVPALILPEYHPSPPVPPPIPAIRHRTPSPPPPPLPSSTPPPVSSEHEEINVRQSSTLSGGYTLSIDRFYSSSSTVSSRKQFNETRDLLSKSLKLSPPNTVTFNI
The following text describes a protein:
Function:
Member of a network of 50S ribosomal subunit biogenesis factors (ObgE, RluD, RsfS and DarP) which assembles along the 30S-50S interface, preventing incorrect 23S rRNA structures from forming. Promotes peptidyl transferase center (PTC) maturation. Binds pre-50S ribosomal subunits near the 23S rRNA L1 stalk, where it may mediate correct positioning of the L1 stalk. Plays a dual role in the late stages of assembly of the 50S ribosomal subunit; promotes peptidyl transferase center (PTC) maturation by modulating the docking of 23S rRNA helix H68, and maintains the stability of helix H89 with the help of uL16 (rplP), facilitating the final maturation of the PTC (Probable). Overexpression slows growth at 37 degrees Celsius.
Subcellular Localization:
Cytoplasm. Note=Associates with late stage pre-50S ribosomal subunits.
Domain:
Has several regions, N-terminal loop (residues 1-25), a central domain (residues 26-105), joined by linker (residues 105-116) to the C-terminal domain (residues 117-183). The C-terminal domain is not required for function, while the N-terminal loop is; shortening the linker decreases assembly.
Sequence:
MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
The following text describes a protein:
Function:
Putative monooxygenase that may contribute to the degradation of aromatic compounds.
Sequence:
MIVLQAYIKVKPEKREEFLSEAQSLVQHSRAEEGNAQYDLFEKVGEENTFVMLEKWKDEAAMKFHNETAHFQGFVAKGKELLSAPLDVVRTELSE
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which, in association with ADP-ribosyltransferase PARP9, plays a role in DNA damage repair and in interferon-mediated antiviral responses. Monoubiquitinates several histones, including histone H2A, H2B, H3 and H4. In response to DNA damage, mediates monoubiquitination of 'Lys-91' of histone H4 (H4K91ub1). The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 'Lys-20' methylation (H4K20me). PARP1-dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites. By monoubiquitinating histone H2B H2BC9/H2BJ and thereby promoting chromatin remodeling, positively regulates STAT1-dependent interferon-stimulated gene transcription and thus STAT1-mediated control of viral replication. Independently of its catalytic activity, promotes the sorting of chemokine receptor CXCR4 from early endosome to lysosome following CXCL12 stimulation by reducing E3 ligase ITCH activity and thus ITCH-mediated ubiquitination of endosomal sorting complex required for transport ESCRT-0 components HGS and STAM. In addition, required for the recruitment of HGS and STAM to early endosomes.
Subcellular Localization:
Cytoplasm. Nucleus. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to the nucleus in response to IFNG or IFNB1 stimulation. Localizes at sites of DNA damage in a PARP1-dependent manner. Localization to early endosomes is increased upon CXCL12 stimulation where it co-localizes with ITCH, CXCL4, HGS and STAM. A minor proportion localizes to lysosomes.
Sequence:
MASSPDPPSPLLVRLRESIPKAHRKLEIYFQSRASGGGECSVQPVGPSAPDTYEVKFLKKADKEKVLKKSEHEMLVHNKPVTIVLETTKKPVEDLRPRLPSLTQPVETPSSRPPSLTGSLDEALCDDIHPQDGLVSNSVDSVVQKIFLAVTAELNCDLLSKEQRASITTVCPHIIKSMEGSDGIKKVCGNFKDIEKIHHFLSEQLLEREQKRKGSEQKRKCAPQKHTPPDVEREPPDQSSIQVPVLLLEYFKHVNPGRLEFIEYKFGVNIEIQASSPNMVTVGFTSSPFGNVEEASQSFVRDFQKCSQSLKQDCISLEEHQRAKEVRQELSRCFPKLLIKGQGRTLTLLGSPADISAATEKVSQGLGLRPVKITASGYTTGIEVDSTRFKLLEPELLQEISEIEQKFNTRGKVQEKGQKTCILFVPKDKDLDLSVQSYTGFTDAFQRATWQLRTEVLSLKGLGKERARLHNTKFADNFKKEHPNVHFVTSQESVTLTGLPHHLAQAMQYVSKRMGLAPSSGEKLAMDQETPMEISSSDPHGDQQENAALPAPRGTSSSPAASKGTEDYCVICMDTISNKHVLPKCKHEFCTSCISKAMLIKPVCPVCLTSYGIQKGNQPEGTMSYSTQKGSLPGYEGCGTIVINYEIKDGIQTKEHPNPGKAYHGTRRTAYLPDNTEGRKVLDLLHEAFKHRLTFTIGYSRATGVSDVITWNDIHHKTSKFGGPANFGYPDPDYLKRVKEELKAKGIE
The following text describes a protein:
Function:
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Subcellular Localization:
Nucleus.
Sequence:
MSAKLRVEELRAELQRRGLDASGTKPALVLRLDVAIREEEKEAASAAEICNVDGIDGVVMDGEAESKSKRKRKRHGEGENEEENDILDVAKLQSMGYRELQALAKARGLNTNGGKKDVLQRLLSSPATSVVDCGIQDKKEVAEADDGKVEELKKKKIVTDVMLDAAQLQGMGYRELQALAKARGLAANGIKKDVIERLLSTPANSVAVADGGFQDKKKLAKGGVGEVEEEVKKEKIVKATKKGAAVLDEHIPDDIKMTYHVLQVGDEIYDATLNQTNVGDNNNKYYIIQALESDAGGSFMVFNRWGRVGARGQQKLHPCSTRDEAIDEFEGKFEDKTKNSWSDRKNFECYAKKYTWLEMDYGEVDKETTQVQKKGSITDQIKETKLETRTAQFISLICNISMMKQQMMEIGYNADKLPLGKLSKSTILKGYDVLKRISNVISRADRRQLEQLTGEFYTVIPHDFGFKKMREFLIDTPQKLKAKLEMVEALGEIEIATKLLEDDSSDQEDPLYARYKQLHCDFTPLEVHSKEYSMIKTYLTNTHGKTHSGYTIDILQMFKVSRHGETERFQKFASAGNRMLLWHGSRLSNWAGIFSQGLRIAPPEAPVTGYMFGKGVYFADMFSKSANYCYASQTSRSGVLLLCEVALGDMNELLNAKYDADNLPKGKLSTKGVGQMAPAESKVTEDGVVVPLGKPKEEPSKRGSLLYNEYIVYNVEQIRMRYVLHVSFNFKGGR
The following text describes a protein:
Function:
Transcription factor which binds a motif with the core sequence 5'-GTATCA-3'. Plays a role in head morphogenesis. Involved in embryonic development. Required for cell specification of the RIA interneurons. May cooperate with the transcription factor vab-3 and phosphatase eya-1 to repress transcription factor ets-5 expression in non BAG neuronal cells.
Subcellular Localization:
Nucleus.
Sequence:
MFTPEQFTKVMSQLGNFSQLGQMFQPGNVAMLQALQANGASSTPSLFPAMPSVIPSLAAPSSPTTSNLTADQIVKTCEQLETDGDVDGLFRFMCTIPPQKTQEVAGNEAFLRARALVCFHASHFRELYAILENNKFSPKYHPKLQEMWHEAHYREQEKNRGKSLCAVDKYRVRKKYPMPRTIWDGEQKTHCFKERTRSLLREWYLKDPYPNPPKKKELANATGLTQMQVGNWFKNRRQRDRAAAAKNKQNIIGVELKKTSSDMSDSDDDFEDSMTDSPSPIDEPKDLSKSHIPKLSPTLLPKMATPFDMFAAAANPLMMLNLNPALYMQFHNFFNTMRNPQIDEEENSETTVEVEADIEPPKKRSKLSIDEILNIKSEVSPSQCSPCSNESLSPKRAVKTEEVKKEDDEAAEEDSRSVKSETSEDPKHSSPKSTTSQSE
The following text describes a protein:
Function:
Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.
Subcellular Localization:
Nucleus.
Sequence:
MGKRKSRTSNKLTAKPKKQLETDFTCPFCSHLGSVQCDIFLKEHQPFVVASCSICTESYTTKAHALTEPVDVYSEWIDSCREANKGVVAPRPDLDSEAKRRRKTEDDGS
The following text describes a protein:
Function:
Acts as a co-chaperone for HSP90.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MCSRQPEVLWAQRSEKVYLTISLPEAKDVSLKCEPDGVFNFSAVGVNGDSFSVTVQIFGNISPEV
The following text describes a protein:
Function:
Replicates the viral genomic DNA. This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction for proofreading purpose.
Miscellaneous:
MISCELLANEOUS: This DNA polymerase requires a protein as a primer.
Domain:
The N-terminus contains the 3'-5' exonuclease activity and the C-terminus contains the polymerase activity.
Sequence:
MPRRSRKKVEYKIAAFDFETDPFKHDRIPKPFSWGFYNGEIYKDYWGDDCIEQFIYWLDTIEEPHVIYAHNGGKFDFLFLMKYFRGKLKIVNGRILEVEHGIHKFRDSYAILPVPLAASDEKIEIDYGKMERETREQHKAEILEYLKGDCVTLHKMVSLFIAEFGMRLTIGGTAMNELKQFHPYDPVRKGFDEAMRPFYFGGRCQAFEKGIIEDDIKVYDVNSMYPHAMRNFRHPFSDEFYEANEITEETYFIEWEGENNGAVPVRTKTGLDFNQRSGIFHTSIHEWRAGIDTGTIKPNRIIRTINFTETTTFGAFIDHFFSKRDAAKKAGDLFHNIFYKLILNSSYGKFAQNPENYKEWCITEGGIYLEGYDGEGCEVQEHLDYILWGRPAEMFNYFNVAVAASITGAARSVLLRALAQAERPLYCDTDSIICRDLKNVPLDAYQLGAWDLEATGDKIAIAGKKLYALYAGDNCVKIASKGASLVPRDIGFLMPPDMEPKAAKKVAQQKAKNIGGEKILKVANGGVYDFVNDAPSFKLNGNVQFIKRTIKGT
The following text describes a protein:
Function:
Plays a critical role in cell cycle progression.
Subcellular Localization:
Cytoplasm.
Sequence:
MPKYKQRRRKLKAKAKRMSKKKEAAVVSPKLLTPSPPLPEPERVVTSAADIPQSRNWLRPSWNLRFPNIKDAINLWTNRAWCIYSCCQTCVAQSLEVLKDALFPSRVYHRELHSLKQQLCVLKRELCKLRENLKSISENSSCSSCCHKCCPSDKLTTVPACAPTTNGESQTVLSSTQPQPANHPPSPPPLPPPPPPPPPLPPPPPPLAPLLLRKSGTTKALQVEPLKKDGPMHITVKDLLNVKLKKTQSVDERKKLVPSPPEERTPLVTVSDLQHVTLKPNSRVSATRIKNVLITPGKSQIDLRKLLRKVQVERSPGGTPLNNKENMDTGTGLTPVMTRALRRKFQLAHPQSPTQSLPLSTSSFDEQN
The following text describes a protein:
Function:
Involved in the transfer of Cu(2+) ions to the apo form of o-aminophenol oxidase GriF in the grixazone biosynthetic pathway.
Sequence:
MPMNRREMVMATTGAALAAAAAVPLLSGGEGEGAAEAAAAPAKATGRGREHTERYLGRSIRVAAPADGGGVFIDGRPLHIMKFADDAYLSSMCHYEMAPTPLHAARRAVEELRGAALQPSTHGTHVTHL
The following text describes a protein:
Function:
Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSETLVLHLKVPTERFREVLSSLKEKQNFTASPSSQPKPQERPFQMKKPRAPYGMGPRAMKRREKAEKEKLGVVNDELAESSKPSSGAATPTRSAPKSSAGLINSGLRALDRSGKPCRRWEKKPISIRSISTIVWKLPLWIGTPDSIPNTPELPVKTTLDSVNEIAAALSTHAESSPMDATSPVDSMPESATGI
The following text describes a protein:
Function:
Major facilitator-type transporter, part of the hnx cluster involved in the purine degradation. The nicotinate hydroxylase hnxS accepts nicotinate as a substrate and catalyzes the first step of nicotinate catabolism. The major facilitator-type transporters hxnP and hxnZ are probably involved in the uptake of nicotinate-derived metabolites, and the oxidoreductases hxnT and hxnY in the further metabolism of 6-OH nicotinic acid.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MGATATDIEKVPSAGTPDEPKAGETNVYVDTEAEKSFVRKVDFFVLPMLCLMYFFDCMDRSNLANAKTDGLEEDINLKGNEYSLLILLFYIPFGLFDLPWNLLIKRYSARIMLSLRRYAVTVVWGICALCQCAANNFGGLLAIRIILGVFEAGFFAGSTFYFTLFYTRNEMGFRLAVLQSFAVLASAFSGLISFGLFQINHSAVKGWQWLFIVEGAMTLIIGVIGFWWLPDTAQSAWFLTQRERDAASARLLRDTSAEIETKLELKAAFQTWSDWKFPIWAVITFSYPVAYATAMNFFPIIVARLGYSVVKTNLWTVAPNLVGAVVLLVVAKSSDIFRERSLHIIFSLTVSLVGMLILASIDVSHNKGVSYFACFLLASGAYIPTCLVHAWHNNNNTNENSRAANTGFFVGLGNIAGVLSAATFRTEYAPKYVPTLVATCACNGVCILATAFMGTWMRLENRRKDKEQGARIVAGQVETRMLADGEKSPEWRYFL
The following text describes a protein:
Function:
Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB and stimulates the proliferation of T-cells. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein; [Tumor necrosis factor ligand superfamily member 14, soluble form]: Secreted.
Sequence:
MESVVQPSVFVVDGQTDIPFRRLEQNHRRRRCGTVQVSLALVLLLGAGLATQGWFLLRLHQRLGDIVAHLPDGGKGSWEKLIQDQRSHQANPAAHLTGANASLIGIGGPLLWETRLGLAFLRGLTYHDGALVTMEPGYYYVYSKVQLSGVGCPQGLANGLPITHGLYKRTSRYPKELELLVSRRSPCGRANSSRVWWDSSFLGGVVHLEAGEEVVVRVPGNRLVRPRDGTRSYFGAFMV
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MGGNDNNGGQGQGKKYALLGVSCILLVAMVGAVAVSLTKGDDKEQTAQISNSQKNVDMLCQSTEYKETCHKSLENASSTDTKELIKAAFSATAEELRKHINNSALYQELGKDSMTKQAMEICNEVLDYAVDGIHKSVGTLDQFDFHKLSEYAFDIKVWLTGTLSHQQTCLDGFVNTTTKAGETMTKVLKTSMELSSNAIDMMDVVSHFFKGFDPSQYGVSRRLLSDDGIPSWVSDGHRHLLAGGNVKADAVVAQDGSGQFKTLTDALKTVPPQNAVPFVIHVKAGVYKETVNVAKEMNYVTVIGDGPTKTKFTGSLNYADGPGADTNLRVKWHGVKVLTSNVAAEYYPGKFFEIVNATARDTWIVKSGVPYSLGPM
The following text describes a protein:
Function:
GTPase-activating protein for the ADP ribosylation factor family (Probable). Regulates endosome recycling downstream of rab-10 and upstream of arf-6; [Truncated cnt-1]: Promotes apoptosis during embryonic development. Produced by caspase ced-3-mediated cleavage, and translocates to the plasma membrane where it prevents the activation of the prosurvival Akt-1/2 and sgk-1 signaling pathway by competing with Akt-1/2 for the binding to PtdIns(3,4,5)P3.
Subcellular Localization:
Cytoplasm. Recycling endosome membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Apical cell membrane; Peripheral membrane protein. Note=Colocalizes with rab-10, rab-8, rab-35 and clathrin chc-1 on recycling endosomes in the intestinal epithelium. Partially colocalizes with early endosome marker rab-5 and to a lesser extent with late endosome marker rme-1. Colocalizes with arf-6 on endosomes of the basolateral recycling pathway; [Truncated cnt-1]: Cell membrane; Peripheral membrane protein. Note=Binds PtdIns(3,4,5)P3 at the plasma membrane.
Domain:
The PH domain binds phosphatidylinositol phosphate (PIP), phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3), and to a lesser extent phosphatidic acid and cardiolipin.
Sequence:
MTVSNNGMAMPSVPPKIDCSEAIQDSPKFRATVAQHAMYFNRLENRLNEMLRHITAMIDFSKNYTNTFYKLTVSVNQLCDESFSGNPLASTTFQGLSEAYAHTVNLFRTYFDHSNVVTFTKLSNFIKIELTKVAESRAHFENMSQSMDDALVKNASISRQKPADATEGRNALTAVGTCFAHTTLDYVANINIAHAHKDHMILDALWTLVRESSAFFSKGHATFDEWTAADNGAIADTIQTFAAKSKLIERKMQDVHSLVPKEMFQHPSGMPIEPDVMMEGYLYKRSSNAFKTWNRRWFQIKDKQLLYSHRSTDLEPATIMEENLRICLVRPAPSNIDRIGCFELVTPTRIHLLQADSESLCQDWMRALQRTILALHEGDSVDVASTSPRNKTTSMSSGVTLTSANAISPLSNAMDVTKGRSVSDPASTYTSANTSSISTAAGFSSSTTAFEQVRRVPGNEVCADCGSPAPKWVSINLGVVLCIECSGAHRSLGVQTSKVRSLCMDSIDNELRDVLLALGNRQVNEIFLAHLPPADSIVPPQINEKSARPAREAWIKAKYVERRFAVAEDTRARSSATNRQEHLKHKTSIGGNSSSNGVNRSSSYADVQDAESGGLLDADPWSADLSVPVPTASKRLSACGSDTNLDAIGSSSIDTKTVEWDSVKEACECGDLLALMTAYAQGFDLNALHNGTTALHIATRNGQTAAVEFLLLNGAKINMLDEKLNTPLHLAAKEGHTLPVCQLLKRGADSNLANVDSKTPLDIAMECTHADIVTLFRVTIMRNDFNADFNNPMDETVEAVISDIARRAATEKEQKKTESLKSTSDI
The following text describes a protein:
Function:
Required for association of the cohesin complex with chromatin during interphase. Plays a role in sister chromatid cohesion and normal progression through prometaphase.
Subcellular Localization:
Nucleus, nucleoplasm.
Sequence:
MNQDEVAKALLGMAEALRTQDPPKLKMAIKCARSAVKLDTNDETRARCNLQLGKLLFFYTENFDLARNHLQLAYDKMTQMGDFAARERMHAISMIADLYIHYQNWPARPIKDALKHEILHTRGFQTLTNKLLFQLIFLALEADPADKAHLEVIKDFFVCTKLAYMFYQGKSRTSRQLLRQIQKQQTSGETTIQGIRWLGEASMTLFACVMNITSALVQSNPGRLEKYFNLVVKHADDAIYKYTRTPQEPGVVRCINMIKMTTLEMMACCNVMACRPEQTLSNVRDMLEMCNRSSGPLLYRFYAPHIQYILYHFGALEFFYHTQFSWFQNIGGLQCCYFHQYDYAEKHFVSALNFINPDDTMSHNKIAFINLNLAWTYLNQLKMADYYEVAERLTAPKIAGCSQMLKSNWFDGDPFKLLPRDDASLLL
The following text describes a protein:
Function:
Acts in glucose-induced cAMP signaling by catalyzing the synthesis of the second messenger, cAMP to activate PKA signaling and repress sexual development and gluconeogenesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MDQSKRLLKSAVPNPPEHFKTGISWLDDLDEKDDDSATSVNYDIPEITEANLCNDSHEALSPCTQPVGNSGRPVEAFKTYPSTPAVPSKSVLFHFYEPDENFSLSDTGRTKSDTALAARESSEKSEVPRDTRSAGIKPYKENNSSNCAISKEAGLRRLIDKDRESFDKNLNQSFTNLTFPEPISDDSDSVEFQRDSLNNNWPASLEGSIHELPRNSDDDGIPASAAHILDLDYHRDSYDSPWKKFLPYPSILSDDSWKAPESWGTSLPTEAIPKQVFTTRFFARPSLGNRKKEFFLRVYRDDRTSVSFICPIGIQTHEVIKLLARLFFLPSSANFYLLLIQFNTERILLPHEQPCIIFERLLSLFGCKVTSDEEINEEDNYSVARLVFTTMDIGADVLRKFSEKKITANLDISRSNLEVIPVKIYPYAHELISLNVSHNLSLDLPLDFMERCVKLKRLDISNNLRSPRGKPITALRQLEVLNMSRNDIYELDPLIFSGLSRNSLKELNIANNKLFFLPHSTRYLVNLTYLDLSYNNFVTFPLIITELSQLETLNFSHNLLSQISSKIGSLVKLKHLYLQFNDLSNRLPQEIGLLKNLETIDLSYNAITNIASLSECPKLNSINVACNLLSFYEYSNPSATFIDFSFCPLTTIDPAFSYSNLVYFDISHAKLIGLKDSVIETLVNVETVKVNYNHFTSISDAISAMQNLKYLSCTNCEMSYVSPNLGKLKHLVHLDLHANNIKIFPEEVWQVSSLKVVNLSSNILEKIKLPVATSKKLTRTISQLKIMRTLSGNPVSSLSSQEFVMPTVEELYLVDNRLGNDCFTALEYFKCLKVLNLSYNYLTEIPSKFFQNFSDLKHLFVSGNELANLSISSTAQVLLETLYANGNRLSSFPKNEALSKSLRFLDISTNNLQNLAVEKAEKKSLTKLPQLEYLNLSGNTWFRFSEHEDTNFTKSYLKNLKFLSIMDLNTKFSNAPSDVLNHFIQRNSPQPNILRYGVCGYLSRSIPVISACELVVNNFLHPQSSLYCVLDSDISAGKNNRVLKFVYDNLASCLAHEINAADSSSEQICNALRRGFLRLNKKLGNVIHYDLRKSSEGDVDSNYVTTMNISEKGYSMDSSCLDIGVSIILVYVRDTRAFVANVGTSMAIMSTRNDSEPTTLSVMHDVYNRDEIRRIVDSCGFISGEIKSTTTRAIGRLSQFPGVQAVPYVNVQYLSELNEFIILANQEFWSVLSKRTVIDVVRANRHSPLLASTKLRDYAIAYGAEKNVLVVIVELNGLFEENSLNFNQLRGDEKTLAISEKNDNMSFVQDLPDDSSLARMNREVSPPKGCIAMVFTDIKNSTLLWERHPIAMRSAIKTHNTIMRRQLRATGGYEVKTEGDAFMVCFQTVPAALLWCFSVQLQLLSADWPNEIVESVQGRLVLGSKNEVLYRGLSVRIGVNYGVTVSELDPITRRMDYYGPVVNRTSRVVSVADGGQIAVSAEVVSVLNQLDSETMSSEKTNVNEMEVRALKQIGYIIHNLGEFKLKGLDTTEMISLVYPVQLQGRLERLIKSRSLGTPTALPETQTYTPVRSRSNSLRPMLARLSDSKSVHGEEGGSGKRSVSSLRNVSPSESTGGYEGCIFDDQQYQLLYELCERLEDHAAILHGFPEPPPCDTGLAAPVNQAEEYSLFYRLTLRIENTIYCVSQMLGHTG
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Sequence:
MVLQAFTGVGLGFKRNFSSGLHLLRAWKQIEVRKLAKQPEYKVGDEKPRYIPSKRKTVPDYKYGESRIFKQSNNGLYGGSFIQFGNNISESKTKTRRTWLPNIVRKSLWSEALQKDVRIKLTAKVLRTISKEGGLDNYLTKDKSARIKELGPKGWELRYRVLVARERQLNPPHKDAQAITTEDGRTVTVYYEVPLNGTTLRITCGRRRLLFHLFNREHREHKADGLHLTFKSFLDKHRDTPVPDIVSRLVALGHSMEELTV
The following text describes a protein:
Function:
May act in the sexual differentiation pathway.
Miscellaneous:
MISCELLANEOUS: Present with 96655 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MSQKACYVCGKIGHLAEDCDSERLCYNCNKPGHVQTDCTMPRTVEFKQCYNCGETGHVRSECTVQRCFNCNQTGHISRECPEPKKTSRFSKVSCYKCGGPNHMAKDCMKEDGISGLKCYTCGQAGHMSRDCQNDRLCYNCNETGHISKDCPKA
The following text describes a protein:
Function:
Involved in ribosome biogenesis and cell polarity. Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in correct positioning of the mitotic spindle during mitosis.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSNSLEERLRANSSAFDGLLALIPAKYYYDEKSQEQWKAKKKTKEQSKNDKLKKLDPEQRDDETSSTLEVMKKKEKDAKPVVLPGEKFKHMKMQKQKEATSKVEGDSDLNVEVNDPMIIAPDEDEEEEEDIKVIFDDEGNEIPLESKKDTTEPDRSVEKKSITEEEKLQRKKNLEALRSKLQAKISDMKSKRKAPGSREAILAQRKRKEELKKRKRLESEQEQDQDEIASDSDMEDIDSDLENNSKKRFKKGKKDSEINADGVMFQNIIFDDGARATSDLQRLRKAGRTKGPAKNDVKSHLKLLEAKKNKMEAKDELEQIKQKEKEKWQKAMLQAEGIKIRDDEKLLRKAIKRKEAQKRKSAIEWSERKRVVEDTISERQKRREENLRIRKDNKGKKRNKQEKMKRKYVGSAVPKKRAGFEGRLKTGKKKGGPK
The following text describes a protein:
Function:
Involved in the perception of symbiotic fungi and bacteria. Part of the perception/transduction system leading to nodulation or mycorrhizal infection. Phosphorylates PUB1.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MMELQVIRIFRLVVAFVLCLCIFIRSASSATKGFESIACCADSNYTDPKTTLTYTTDHIWFSDKRSCRQIPEILFSHRSNKNVRKFEIYEGKRCYNLPTVKDQVYLIRGIFPFDSLNSSFYVSIGVTELGELRSSRLEDLEIEGVFRATKDYIDFCLLKEDVNPFISQIELRPLPEEYLHGFGTSVLKLISRNNLGDTNDDIRFPDDQNDRIWKRKETSTPTSALPLSFNVSNVDLKDSVTPPLQVLQTALTHPERLEFVHDGLETDDYEYSVFLHFLELNGTVRAGQRVFDIYLNNEIKKEKFDVLAGGSKNSYTALNISANGSLNITLVKASGSEFGPLLNAYEILQARSWIEETNQKDLEVIQKMREELLLHNQENEALESWSGDPCMIFPWKGITCDDSTGSSIITKLDLSSNNLKGAIPSIVTKMTNLQILNLSHNQFDMLFPSFPPSSLLISLDLSYNDLSGWLPESIISLPHLKSLYFGCNPSMSDEDTTKLNSSLINTDYGRCKAKKPKFGQVFVIGAITSGSLLITLAVGILFFCRYRHKSITLEGFGKTYPMATNIIFSLPSKDDFFIKSVSVKPFTLEYIEQATEQYKTLIGEGGFGSVYRGTLDDGQEVAVKVRSSTSTQGTREFDNELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLYGEASKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIHRDVKSSNILLDQSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELEDALIIENNASEYMKSIDSLGGSNRYSIVMDKRALPSTTSTAESTITTQTLSHPQPR