lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May regulate neuronal differentiation, polarization and axon guidance.
Sequence:
MGLLLLLWACAAAAGAAVGFGMDPDLQIDIITELDLVNTTIGVTQVPGLHNASKAFLFQDVEREIHAAPHVSEKLVHLFRNKSEFTFLVTLQQKTSTSGVILSIRELEHSYFELESSGLRDEIRYHYRFNGKSRTEVFPYRLADGQWHRIAVSLSASHLLLHVDCNRIYERIIDPPETNLIPESNLWLGQRNRKHGFFKGVIQDVKVVFIPNGYITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAEARLSRLEDCHCEKTCQVNGLIYRDKDSWFEDDHCRNCTCKSGVVECRRMSCPPLDCPPDALPVHVDSQCCKVCKAKCIYGGKVLAEGQRVLAKSCRECQNGVLVKVTETCPPLNCSEKDHVLPENQCCSVCRGHNFCAEGHRCGENSECKNWNTKATCECKNGYLSVQGDSAYCEDIDECTAKMHYCHANTMCVNLPGSYRCDCVRGYVRVDDFSCTEHDECGSGRHNCDENAICTNSVRGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGNHCEKDIDECAEGIIECHNHSRCVNLPGWYHCECRSGFHDNGSYSLSGESCVDIDECALKTHTCWNDSACVNLAGGFDCLCPSGPSCTGDCLHEGGFKRNGQVWTLREDRCSVCSCKDGKIFCRRTACDCENPSADLFCCPECDTRVTSQCLDQTGHKLYRSGDNWTYSCQQCRCLEGEVDCWPLLCPNLNCEYTATSEGECCPHCVSDPCLADNITYDIRKTCLDGYGITRLSGAVWTMVGSPCTTCKCKNGSVCCSVDLECLNNN
The following text describes a protein:
Function:
Functions as a component of both the DNA-binding general transcription initiation factor complex TFIID and the transcription coactivator SAGA complex. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription. SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription. At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B. SAGA interacts with DNA via upstream activating sequences (UASs).
Subcellular Localization:
Nucleus.
Sequence:
MSDTKPPSTLPQSQPPPNSQDQSSEAIVVPKLEPDSDATALDTSIEQEAVMAGPSVNSAAAGPDAGAAPGAGVGDDQIGNPVQAPTSVDAAATSKKETSLREFLGKMDDYAPIIPDAVTAHYLTLAGLPPPGHGPNQTPPHLARLLALATQKFIADIAADSYQYARIRASNSSSASNPMGSLNAASGLGLAGAGGAGAGSAGGAGTGGAGETGKGGSKAGTHLGIQRPGFGGGGSGGSGQGRTVLTMEDLGMAVAEYGVSVKRGEFYR
The following text describes a protein:
Function:
DNA-binding protein that specifically recognizes a negative element (S1F) within the RPS1 promoter.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Nucleus.
Sequence:
MSFLPSLFSVSILLCFFCSLNEATTDNGIVSLTRDLSVPNSGAGKVLYANPIRFRQPGTHSPASFSTFFSFSITNINPSSIGGGLAFVITPDGNTVGAAGGSLGLAGPSVSKFVAVEYDTLMDVDFKDINSNHVGFDVNGVVSSVSGDLGTVDIDLKSGNTVNSWIEYDGLSRVFNVSVSYSNLKPKSPVLSFPLDLDRYVNDFMFVGFSGSTQGSTESHSIEWWSFRSSFGSGPGSGSGPSPPTANLPSSSAVPISSQSKTPPTCRNHLCKENRGAIAGVVTAGAFFLALFAGGLHDSFASEIIKAPKEFSYKELKAATKSFNESRSIGHGAFGVVYRGVLPETGDVVAVKRCSHSSQDKKNEFLSELSIIGSLRHRNLVRLQGWCHERGEILLVYDLMPNGSLDKALFESRFPLPWDHRKKILLGVASALAYLHRECENQVIHRDVKSSNIMLDENFNAKLGDFGLARQIEHDKSPEATVAAGTMGYLAPEYLLTGRATEKTDVFSYGAVVLEVVTGRRPIEKDLNAQRQNVGANPNLVEWVWGLYKEGKVTAAADSRLEGKFDEGEMWRVMVVGLACSHPDPEARPTMRSVVQMLIGEADVPVVPKSRPTMSFSTSHLLLSLQDTLSDCNTLALNSSRSSSWSVPEHNVMIRGDDDHMRFRIVFMDREDFARKAAAEARGLNPGLIVLLVIGGPLVVFLVANIVLYVHAQKNLPPKKKKPVSKKKLKREKLKQGVSVPGE
The following text describes a protein:
Function:
Probable catalytic subunit of the Tip60 chromatin-remodeling complex. Plays a role in acetylation of nucleosomal histone H4 and perhaps also H2A, probably acting as a component of the Tip60 histone acetyltransferase complex. Acts in the determination of vulval and distal tip cell (DTC) precursor cell fates. Involved in the positive regulation of transcription factor daf-16, probably acting by histone acetylation; thereby modulating stress resistance.
Subcellular Localization:
Nucleus.
Sequence:
MTEPKKEIIEDENHGISKKIPTDPRQYEKVTEGCRLLVMMASQEEERWAEVISRCRAANGSIKFYVHYIDCNRRLDEWVQSDRLNLASCELPKKGGKKGAHLREENRDSNENEGKKSGRKRKIPLLPMDDLKAESVDPLQAISTMTSGSTPSLRGSMSMVGHSEDAMTRIRNVECIELGRSRIQPWYFAPYPQQLTSLDCIYICEFCLKYLKSKTCLKRHMEKCAMCHPPGNQIYSHDKLSFFEIDGRKNKSYAQNLCLLAKLFLDHKTLYYDTDPFLFYVLTEEDEKGHHIVGYFSKEKESAEEYNVACILVLPPFQKKGYGSLLIEFSYELSKIEQKTGSPEKPLSDLGLLSYRSYWSMAIMKELFAFKRRHPGEDITVQDISQSTSIKREDVVSTLQQLDLYKYYKGSYIIVISDEKRQVYEKRIEAAKKKTRINPAALQWRPKEYGKKRAQIMF
The following text describes a protein:
Function:
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Domain:
The transmembrane domain is necessary for interaction with KCNMA1.
Sequence:
MRPRAPACAAAALGLCSLLLLLAPGHACPAGCACTDPHTVDCRDRGLPSVPDPFPLDVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQCSLPMESRRISLRELSEASFSECRFSLSLTDLCIIIFSGVAVSIAAIISSFFLATVVQCLQRCAPNKDAEDEDEDKDD
The following text describes a protein:
Function:
Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for the primary monoamines methylamine and benzylamine. Could also act on 2-phenylethylamine but much less efficiently. At endothelial cells surface can also function as a cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion.
Sequence:
MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSHQLFADLSREELTAVMRFLTQQLGPGLVDAAQAQPSDNCVFSVELQLPPKAAALAHLDRGSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDMTVERHGGPLPYHRRPVLFQEYLDIDQMIFDRELPQASGLLHHCCFYKRRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFPHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSWSLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERVAYEVSVQAALAIYGGNSPSALRSRYIDSGFGLGHFSTPLTHGVDCPYLATYVDWHFLFESQAAKTIRDAFCIFEQNQGLPLQRHHSDFYSHYFGGLAETVLVVRSVSTMLNYDYVWDMVFHPNGAIEIRLHTTGYISSAFPFGAAQRYGNKVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMAFVPMAVPWSPEHQMQRMEVTRKLLETEEQATFPMGGATPRYLYLASNHSNKWGHPRGYRIQVRSFSGEPLPQNSSVERGFSWGRYQLAVTQRKEEEPSSTSIYNLNDPWTPTVDFTDFINNETIAGQDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGACEVNPLACLPQAAACCPTPPCPSPRGCFSTTKRPGMGMGQSGSRARV
The following text describes a protein:
Function:
Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions, including production of degradative enzymes such as the neutral and alkaline proteases, flagellum formation, biofilm formation, and competence for DNA uptake. Positively or negatively regulates expression of many different genes. The phosphorylated form is required for synthesis of degradative enzymes, flagellum formation and biofilm formation. The unphosphorylated form is required for expression of genetic competence, via induction of comK.
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity.
Sequence:
MTKVNIVIIDDHQLFREGVKRILDFEPTFEVVAEGDDGDEAARIVEHYHPDVVIMDINMPNVNGVEATKQLVELYPESKVIILSIHDDENYVTHALKTGARGYLLKEMDADTLIEAVKVVAEGGSYLHPKVTHNLVNEFRRLATSGVSAHPQHEVYPEIRRPLHILTRRECEVLQMLADGKSNRGIGESLFISEKTVKNHVSNILQKMNVNDRTQAVVVAIKNGWVEMR
The following text describes a protein:
Function:
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
Subcellular Localization:
Cytoplasm.
Sequence:
MSDSKHLPTHLFLERAREFVEVANNTQSSLNMTMKRAIEHDPVEKNQVYDATNQPLADVSCKSGLVATNQKEYPLLVRLTCGSREKKLKCSSLVRADELDKFWQDYVAVLKGGMSNLVKTKKKKVKTKGKKAGVKK
The following text describes a protein:
Function:
Probable ATP-binding RNA helicase which plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity).
Subcellular Localization:
Cytoplasm. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Sequence:
MEDDDVADFFDFSKPFKRTVVSGGYINGAVKPQKLNIQTLPERAHQGTEYAEKFCREEEARLMEGWVDETLNKSTASRLEQVDDMSSVMEEDTQHLQRVRAKELMEPLFSRYNFTVTPNRLTIHQSKQDILKAIRENPVVVLQGMTGCGKTTQVPQYLLEDAYNRKEWCNIVVTQPRKIAASSIARRVAEERNCALGSLVGFKVGLKEMVSEDTRLTYVTTGVLLNKLITSKSISSYTHIILDEVHEREVDMDFLLIIVRRLLATMRNTKIILMSATIESSEFAQYFKIPGPNSLFAPQLAVSNVTQHDVSVYYLEDLEKLRVDFTIKYEQPDVHEKMYFLAAKVAVVCDRFIDEFESASTIDYKPSIIMFLPGINEIERMAEVLRNFLGDSNVNSQEQTKFTILKLHSMLPSEEQALVFTKPSPGYRKVILSTNIAESSITIPDVKFVIDFCLHRVLVADTLNNFTTLRTQWASRNNCIQRAGRCGRVMNGRVYRLVNKHFFEHGMAQSIEPEMVRCPLSNVVLKTKLLDMGPPHTILALAMSPPNLSDVSNTVLQLKELGALLRTAKGVYDLQDGDITYLGNIMSTLPLDIHLAKLVVLGYVFSVLEEAIVIAAGMNVKNIFCQLRTIEALRVKRHFANGSASDGIAILNAYNWWRSIREQGTGGDTTDWCNRYMLDRKSLIEMAELVQEITMRLKTANIRVVSGANNARWTDRERTVVLKVVMAGAFYPNYFIPTCVTDRELSDKMVYTEIGGRDPFSTVFFCGFDHSNYIGPLYRNEIRALLTERKPTSEKHQVKVEFERSTNKIFVQFQYPPDQQSGKSLYEERNSADRVHPGVYEAIKLRQLRHNQSELLVMHHNDAVAYATEHRLGVWRNHEWHPRSVEIPNAHLSVEPPIHWNRVTATVTHVEHPNKFYLRPHDEKNDNIYHDIMEKLNGCDAVLRAFPEGYAFKQRDIVAAPLPNMVTGKMARAKLLQQCLVRGVEHWTVFFMDFGLTAGVSVKSFRQLRGTPLDMFTKFPDRVFLASLAEVQPSAVRSPKDVWMEETIKHFRQLVHGQQFDVEVYSVVNRVTMVVLRHNPDDPIDLTVNRALINSHHAQLSEESYMSKMNHEKRKRVQFEMELDPMYKTQILNDISEQQRFLEDDDVDSLELPRDLLKVRLMLRGPYSPLEVKCSSTVFSGYRKPVIIEKESLNSVLLDTNPQNTHEKLLVAGCVNETSNSRLIARMTTMMPNIPGLPALMTLIFAPTCLVKKDPDETRVVGLLAGLGTDPRTGESMYPEHDMSLAVDIAIDDDDIADINALRYTMDSILHGGHNEQTPMFGEYSIESLMVKVKDYLIKILQRDRPIQDNRSMAHDFSWVKENPSTSTSSQKRLRSTAIDIYTKAIFPLYHNLNLRPMTADRMEFLRQHCKDLHLLTQSRVPLPKGGITCRLCNVTLESDHTLRIHFYSKLHCDLELKINYRR
The following text describes a protein:
Function:
Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction.
Sequence:
MDCGETELNSAAFSSAKSLRVLDLSECSIHKLPDSIGQLKQLRYLNAPRVQHATIPDSITKLLKLIYLKLNESPTILALPESIGDIEGLMYLDLSGCSGIETLPESFGRLKKLVRLDLSNCSRIGGVSVFLENFTELQYLNLSHCPNIGPLSEALGGLSELQYLNISFSSYLVGRQEAEVLGTFSKLEYLNLSSEDCDLQKLPESLGGCVKLKYLNLTGCRHMKELPASFGNLNNLVHLDLTNCGEVNGVPEALGGLTKLQYLNLSWVGPGEKQSLVGLPNVIGNLTEIRYLNLSGCMHCIIEADGNSDTRDQIDSFMDRISTLSNLEHLYLSRNICIGSIPASFCNLRKVHTMDFSSCYDLREIPEYIGTMDSLKTLYLNGCYSLNHSNLCGRSVPGFVVHTVSQLPNLNRLVLRGMESLEEWNTSYSSGQEYVLGYLQIEDCPELRIKSFPPRAERWRIIRSGNVLSCWENYCSDLTGSPEIIQHLSSVETLSLEANDQDDLPEWLGELTSLQKLEMHENMRQLKKLQTLQVSDCNSMASLPRWLGGLTSLKKLDISDCQGLRSLPDSIQKLNNLQELNLYDCSQIEHLVESEENKMEHTDMKERVCVLPTSLKKIEIHECHGIRSLPDGIQQLTNLQKLSIVNCRELVKWCESEENKMKVGHLRLQELY
The following text describes a protein:
Function:
Probable polyketide synthase.
Sequence:
MIKGNNVVIIGVGFRFLKNNTYINNINELLENKIQNELKEIKSSDSISNEIKEFDSSLFFKLDESKDKISEKQILLLKCIWESMENANIDPTNLQTSIKTSVLIGSDQYEPGMPDSIRVSQAFNLKGECLTNNGVGSIVASLKFGYKSIFFGDSKIAIIGGSNRNKNGEIEQVGAFILKGLEDAIADNDNIYCSVRDINEISDLEIPRTDNRYSVNKISESVGIISMIKSFLKFENISKSKLIFNTIVYGPYHSPSFIFSKHFENNYNNNKEIIYNKNISREEDQPSPSLIYKVESQNYLIPFSANSINSLKKVQSIIIEDKNNEFQSTIPFKDFVKHQINSRSIKLKSKSIIIAKDWDELKNIQTSINYSPILNYSNNNNNINDDESVNVFVFCGQGPQYITMMDDLYNNEVFFKKSADLINEKLIKYLGFSPLEKLKSIADCSNLINESTISQPLLFIFNISLFELYKHWGIKPSIIVGHCIGEVFAAYCSGMFDLETACLLVSQRGIAQDSTNGIGKMLSLSIGKNEYQSIIPIENYPNVEFSCFNSPNSIVIGGPEHDLNEISKILLNNGVTATMLSSLASCHTSSQNKTREHLTNLKFKHQQPIVPTFSTVNTKLFDNESTKFDSTHLFNCIALPVYFDETISNIYKYIEDNQLGSKVTFFEMAPHPSLSNYLKEMIPISSKYFNDGDSVSVYSPCHKRKNHHQEFQKTLIDLYLNNFNIDFNCQFGGENRYDKSFKKNTTKLPFYQWCDKSIEINESSKDDSNITFEQLFFKKSAQFIKFSDESLIDRNERLIRYGADSLIIVQIKNWVDRYLKVKNLVTIQQLQNNSINDSIILIEQKYKEFLDGKLISKLEMTKEERKQFWENEMKLDPSIQHLKIVKENDKRVFITGTTGFLGAHMLVHLLKLSNCSVTYCLLRNKSNSTNPINEIINNLKHHKVYDQLNQIQLSKIVPVIGDLAKARLGLSDKDYSLIANNANLIINSGADLNLESDYNSNKPVNVDGIVEIIKLSISDHINGIQKPIVNFSTFTVFINQSLNGEEFDESILPSLDNIDNLPAGYMQSKVVGEYLLIEAARRGIPSMLIRPPSIFSHPETGVGLSSDFFQLSVQCCYATGYYPDVDMKVLLTPVDWVSDNTMNLILTDKCWDESNHGKLNIYNVYGDITAPKDIYGPMNKIYNCKPIAFGKWRQMIMDSDVLSCVKFRSFHSMDFHEKHNIDKGLNLSKRTKNLLKSIGSYNENWKVNEKMIISHINYIFNNNN
The following text describes a protein:
Function:
Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X.
Sequence:
MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQGLSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLLDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
The following text describes a protein:
Function:
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.
Subcellular Localization:
Cytoplasm.
Sequence:
MSLDILSTTRIIVKEQVNDWTEAITIASQPLLQEQIIEQGYVQAMIDSVNELGPYIVIAPEIAIAHARPNNDVHQVGLSLLKLNQHVAFCDEDHYASLIFVLSAIDNHSHLSVLQNLATVLGDNQTVQQLLTATNAQDIKNILKEHD
The following text describes a protein:
Function:
Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside. Through these activities regulates the purine nucleoside/nucleotide pools within the cell.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MAENNNNNNNNNNNNVSTPPHQKPHLTTGLRTSSSGLLMDKRRQDEEKFSAEQVAMGKKSPTKLFSAYSLNDLSNPPTDEELNNYKDLPASSLPPIHKREKLRRVFVNRDIKLDRIEFFGFDMDYTLAVYNSPDFEELAYDMVLDKLIDIGYPKSIRKLKYDPNFPTRGLFLDRELGNLLKIDSFGNIIICVHGRTTLSKNRTAEFYPSMRVSSDEIARNRFYLLNTLFTLPEACLYADLVDHLERESGLRLTEEVADEQQQMNSPPLSSLGSESVRIDESNHQPEGDLSFSNLFQDVRTACDLVHNDGSLKTRVLDDLPRYIRKTPDMPVFFDRLRQNKNKVFLLTNSEFYYTNKVMSYMMNGYNPNYQSWRDYFDVIIVGADKPRFFSEGTTIREVDTETGNLRITNVKDRFEQGKVYHGGSLSLFQKLTGAKGSRVLYIGDHIFADIIKSKKTHGWRNLLVVPELQHELEVMNQQKDTTIHLMNLEFIRAEIYRGLDSESTTPPDIEVLHQHLKNTNDKLNFAYNKYFGSLFKNGSKSTFFSMQVQRYADLYTSDYLNLLNYPLFYHFCANSLPLPHESSSFSSFDTSN
The following text describes a protein:
Function:
Component of the DSC E3 ubiquitin ligase complex which is required for the sre1 transcriptional activator proteolytic cleavage to release the soluble transcription factor from the membrane in low oxygen or sterol conditions. The complex also plays an important role in the multivesicular body (MVB) pathway and functions in a post-endoplasmic reticulum pathway for protein degradation.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MSSSALKKWEIVIRFASSIPDLSLEISDAQTTTIHSLFKIVRNRIPECRDKQLKMVFQGRLLSPGFTVERAVRGNWQRDENDDPNIVQKAFIHCIVGPTLTEEELASQDQAQSGLNSNSESPDDLQNAQTGETLRGFDRLREAGFTETEVNNLRSQFHRLRGTNLDSLTEDAIREAEDDWIDNGGQNSSADELDMSYETLLAGVLIGFFGGAIACYFLWERTMFSLRMQLSILVGIICNFAYGLLHSYRW
The following text describes a protein:
Function:
Modulates cell-to-cell trafficking.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell junction, plasmodesma. Note=Co-localizes with the Grapevine fanleaf virus (GFLV) 2B-MP at the base of tubules within modified plasmodesmata.
Sequence:
MFATKTVLFIAVVSLLGTFSSAAVDTFIYGGCSQEKYFPGSPYESNVNSLLTSFVSSASLYTYNNFTTNGISGDSSSVYGLYQCRGDLSSGSGDCARCVARAVSRLGSLCAMASGGALQLEGCFVKYDNTTFLGVEDKTVVVRRCGPPVGYNSDEMTRRDSVVGSLAASSGGSYRVGVSGELQGVAQCTGDLSATECQDCLMEAIGRLRTDCGGAAWGDVYLAKCYARYSARGGHSRANGYGGNRNNNDDDEIEKTLAIIVGLIAGVTLLVVFLSFMAKSCERGKGGK
The following text describes a protein:
Function:
Involved in pre-mRNA splicing as a component of the spliceosome.
Subcellular Localization:
Cytoplasm. Nucleus. Nucleus speckle.
Sequence:
MSNPTSTTHHNIEIQSQDVIKLILQFLKENSLGNSLTALQEETGINLNAVDSKETFLNDVKNGNWDSVLTVVSTLRLSTTLLMDLYEQIVELLHLKEYELCKYLIRKTEPLNYMKLNQQERYLKLENHLQREYIDLGDFYKYGITTEKRRKQLIEQLNNEIITVPSSRLLSLLSQSLHWQKHQGIIPDDCMEFDLFKGEVPFKKIESEEEQITTVLDKTIKFNNKNKPETIKFSPDSKYLLTGSMDGFIEVWDYNTGKLSKSLAYQSNDDFMMHDDAILCIAFSKDGEFLATGSLDNKIKVWQIKSGKCLRKFEPAHTNGVTCLQFSRNSTQILSGSFDSSLKIHGLKSGKALKIFRGHQSFVNDCCFNHDEDRVISCSSDGKIKIWDAKSSDCLQTITPTSVVTVRDISIRSITILLKNPEFLLVCNSSQISIVSMKSQTISKTFTSENSKTFLVCTLSPLQNYLYAVDEDNILYTFDFNSGSLLNKFKIHDQEVISISHHPTKNLLATTGSDCLLKIWKSNSNDNINN
The following text describes a protein:
Function:
This protein is part of an active transport system that transports exogenous cyanate into E.coli cells.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLLVLVLIGLNMRPLLTSVGPLLPQLRQASGMSFSVAALLTALPVVTMGGLALAGSWLHQHVSERRSVAISLLLIAVGALMRELYPQSALLLSSALLGGVGIGIIQAVMPSVIKRRFQQRTPLVMGLWSAALMGGGGLGAAITPWLVQHSETWYQTLAWWALPAVVALFAWWWQSAREVASSHKTTTTPVRVVFTPRAWTLGVYFGLINGGYASLIAWLPAFYIEIGASAQYSGSLLALMTLGQAAGALLMPAMARHQDRRKLLMLALVLQLVGFCGFIWLPMQLPVLWAMVCGLGLGGAFPLCLLLALDHSVQPAIAGKLVAFMQGIGFIIAGLAPWFSGVLRSISGNYLMDWAFHALCVVGLMIITLRFAPVRFPQLWVKEA
The following text describes a protein:
Function:
May be involved in plant development.
Subcellular Localization:
Nucleus.
Sequence:
MLSSSSMSSSSLSARFCFNHECFEFKLDHCRPGWRLRSGDFVDLCDRCASAYEQGKFCDVFHQRASGWRCCESCGKRIHCGCIASASAYTLMDAGGIECLACARKKFALGPNFSPSPSFLFQSPISEKFKDLSINWSSSTRSNQISYQPPSCLDPSVLQFDFRNRGGNNEFSQPASKERVTACTMEKKRGMNDMIGKLMSENSKHYRVSPFPNVNVYHPLISLKEGPCGTQLAFPVPITTPIEKTGHSRLDGSNLWHTRNSSPLSRLHNDLNGGADSPFESKSRNVMAHLETPGKYQVVPRFWPKVSYKNQVLQNQSKESESVVTPLFEKILSATDTGKRLVLPKKYAEAFLPQLSHTKGVPLTVQDPMGKEWRFQFRFWPSSKGRIYVLEGVTPFIQTLQLQAGDTVIFSRLDPERKLILGFRKASITQSSDQADPADMHSPFEVKKSAYITKETPGVECSSGKKKSSMMITRSKRQKVEKGDDNLLKLTWEEAQGFLLPPPNLTPSRVVIEDYEFEEYEEAPIIGKPTDVAGSTCTEVEGLLISPTTTKHPRHRDGCTCIICIQSPSGIGPKHDRCCSCAVCDTNKRRRRSLLLRREKKQMEKEDNARKLLEQLNSDNGLHQSANNSENHERHASPLKVQLDLNFKPEKDEESLPGSNKTTKSETLPHDDTVKSSFTSPSSSSAHSQNNKEDEGKLKTTTEIADTTTTSSM
The following text describes a protein:
Function:
Glycogen-targeting subunit for protein phosphatase 1 (PP1).
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MARTAPVEPPLRHPAPPSPAAGEPRASAEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAATGQDGGGGGADEEDDGEDGDEGEEEEEAFPDPSPPCPVPAGGGFYLVPTFSLPPALGRLERLGRVMVELEALLPPPGAVPGGSGVWVPGGRPPVVRGLVRVLNRSFEKAVHVRASHDGWATFCDHPARYVPRSPPGAGVGGTGAGDPLLDPGLGLGPGQMSASSPDDGGCTDRFAFQLPFAEGASDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLPQQQQLQQLEPQPECQGPVEAEARQLKSCMKPVRRRPFEEEPRMRSADDNTLAEHPDVRESLGPLLAPTPLRPWPQMTLQVPEVMLTSNPQEEGDIPRSNPPVAFTEVRQAPAIRILPATCGLGGPPRDQASGPDASDRAAGSFLEPTQQQVEAAWESGGGRKAPMVGALTDEPARGLEIVSGLDELLGEDTIDQELEQLYLSHLSRLRAVAAAGGGEGTSPTHALGILTDRDLILKWPGPERALNSALAEEITLHYARLGCGVELIKDTEDPDDEGEGEDGLSITPSSPEGGSPKESPPEILSGARSVIATMGDVWVPWAERSSSRCDSPVVLGTQGQFTENPEKGMGKDTKSLHLNRVIVGMSKSPGEAGTESQMEELPTERESSWVPSSEKELPLPVQQEQSPALLGPTGTEVCLSSVAKPHVNSQEEEGGSLNLESPKRSPMPAAPAECACGLAPQLWGPLTQTLGVLAGLVMVPVALNSGVSLLVLVLCLSLAWFS
The following text describes a protein:
Function:
Transcriptional repressor. Cooperates with vent2 in a ventral signaling pathway downstream of bmp4, which antagonizes the Spemann organizer and dorsal mesoderm formation, and leads to ventral mesoderm formation. Acts downstream of bmp4 to repress transcription of foxa4-B/XFD-1'. Binds to DNA with preference for the target sequence 5'-CTATT[T/C]G-3'. Also binds 5'-TGCATTTTG-3' at a lower frequency, and occasionally 5'-TTGATC-3'. Binds to the homeobox 2 (HBX2) repressor element in the promoter of the myf5 gene and represses myf5 transcription in the ventral domain.
Subcellular Localization:
Nucleus.
Domain:
The N-terminal region is required for repressor function.
Sequence:
MVQQGFSIDLILARSKEEATDGKDSMSSRPHIPCAPQPLPPTKYAKEMPRKKDGQDVQEHTTSFQCSLGEQVINRPSANPSLAAMHRSSGSSDEFSPPGSEDDSTESSGRSSQENDTEQREKSPKSDLQRRLRTAFTPQQISKLEQAFNKQRYLGAPERKKLATSLQLSEIQVKTWFQNRRMKLKRQIQDKQHSLVPPPVCYPQTFPYYPGGFPVPLNSGSFYQPRALPFQAPQHSYIPQPLHHHVRMSSHQEQYPPLFGAQYM
The following text describes a protein:
Function:
Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.
Miscellaneous:
MISCELLANEOUS: Inhibition of MYOD1 may be partly due to the ability of EID1 to bind and inhibit EP300 histone acetyltransferase activity.
Subcellular Localization:
Nucleus. Cytoplasm. Note=May shuttle between nucleus and cytoplasm.
Sequence:
MAEMAELCELYEESNELQMDVLPGEGYMEVGRGARGPAPEEGPMEEEAGPAAARAQRGLFPEAGADLEGDEFDDWEDDYEFPEEERWSGAMHRVSAALEEANKVFLRTARAGDALDGGFQARCEKSPFDQLAFIEELFSLMVVNRLTEELGCDEIIDRELMLTREEETT
The following text describes a protein:
Function:
Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MASSSSNPFALLVSTSQEEQGSDVVQDISHPDKAGVMEVDVTAREISLVDAVIQKVFLITVDQEGTTLDEDMPPKCVFLVDMADQLEKERCEPWSWLSWENIDMALFERLLLPDPSFHVLHMTSSIANFDEEEKKAREKDILRYLLASYTRAAALIKNIQNETAEYAEKCQRITVSNAATCLLTPEVYNNQNTRQQLFDILLQSYTKEEGWDIAVKFFHEVAEAIHLDDSLPITEAFTPVLDLLYKQMSQSPSLVEPQNYVWCEIMGFFARQPQLAEVLMDFISPTDPMNAKSYEKTPVGLILSLSCLPRNNEEPQFFEKPSRTSGRDHQATQEYIWQPVGKLTEHIYRIFRSLFKSSLEIRNRLLAWIGRCIHANAGRTKMWSRRLPTFALTYASDSFFLNLSSVLLRFCGPFTKPDTTNIMTVDMSYGSVDLPVGATDAQMSELGVHLVGLPKETRMLHREGEENTSLPTHPPYNFVSGIFFLTHRCLQLGFQTLVERFYTINRELHHVQQAFQEMVQQMGGPRAGPVMSQLHERMDKAMTLFLSIKTSLLEPQFLEMAFNLHIATARIVTQYATSEDVTLLTTPSLPLQGEPPSQLVTIPECLAENLVTYLQFLRRFAEAKFEDGGESLKHVMTFVTVFMGNKSHMSNPHLRAKLAEILEGLMPEENTGSRSTVVPIFHRQKAFNEHPLGEHISRSLISIFVDIEFTGDPHQFEQKFNYRRPMYKVLKYLWSMLQHRTQIKLVAEEAMSHMEDANAPLFLKFINHLINDSIFLLDEALDYVKKIKVLQEQREGGEWLRLQPTERRQQEDSLRQTCAIARFYNIMSNETMSTLVYISNEITDIFIHPVMVNRVAMMFNNFLHKLVGPNKIALKVNDFEEIEFNPKQLVRDICRLYINLGHEQRFCRATAEDEVNYSAMLFIRAEKVLDKISVSRDMIEKMREFADKVKALSETNEMEQEMFADAPDEFIDPLTFNIMEDPVSLPTSDMNIDRSTIARHLLSDQIDPFNRKPLTMEEVRSNPDLKLQIETWKQEQKNKRK
The following text describes a protein:
Function:
Exhibits ester hydrolase activity with a strong preference for long-chain alkyl ester substrates and high selectivity against a variety of short, branched, and substituted esters. Is able to hydrolyze ester bonds within a wide range of p-nitrophenyl derivatives (C2-C14) in vitro, with a strong preference toward substrates of >8 carbons.
Sequence:
MAAQRPLRVLCLAGFRQSERGFREKTGALRKALRGRAELVCLSGLHPVPDPPGPEGARSDFVSCPPEEQPRGWWFSEQEADVFSALEKPAVCRGLEESLGMVAQALNRLGPFDGLLGFSQGAALAALVCALGQAGDPRFPLPRFIILVSGFCPRGIGFKESILQRPLSLPSLHVFGDTDKVIPSQESMQLASRFPGAITLTHSGGHFIPAAAPQRQAYVKFLDQFAE
The following text describes a protein:
Function:
Collaborates with REM4.1 to positively regulate the BCTV and BSCTV susceptibility.
Subcellular Localization:
Cell membrane.
Sequence:
MLTLYHQERSPDATSNDRDETPETVVREVHALTPAPEDNSRTMTATLPPPPAFRGYFSPPRSATTMSEGENFTTISREFNALVIAGSSMENNELMTRDVTQREDERQDELMRIHEDTDHEEETNPLAIVPDQYPGSGLDPGSDNGPGQSRVGSTVQRVKREEVEAKITAWQTAKLAKINNRFKREDAVINGWFNEQVNKANSWMKKIERKLEERKAKAMEKTQNNVAKAQRKAEERRATAEAKRGTEVAKVVEVANLMRALGRPPAKRSFFSFS