lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Promotes reactive oxygen species (ROS) production during drought-induced leaf senescence. In response to abscisic acid (ABA)-mediated drought stress signals, binds directly to the promoters of RBOHC and RBOHE genes, encoding ROS biosynthetic enzymes, resulting in ROS accumulation and triggering leaf senescence via programmed cell death (PCD). ROS-induced leaf senescence sustains plant survival under drought conditions. Involved in heat stress response. Modulates PCD through a ROS-mediated positive feedback control under heat stress conditions. This may provide an adaptation strategy for plant survival under extreme heat stress conditions. Acts as a repressor in preventing anther dehiscence during stamen development by suppressing genes that participate in jasmonic acid (JA) biosynthesis, such as DAD1, AOS, AOC3, OPR3 and 4CLL5/OPCL1.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus. Note=Localized primarily in plasma membrane or endoplasmic reticulum membrane as dormant form and, upon abiotic stress, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP).
Domain:
The NAC domain includes a DNA binding domain and a dimerization domain.
Sequence:
MGRGSVTSLAPGFRFHPTDEELVRYYLKRKICNKPFKFDAISVTDVYKSEPWDLPDKSRLKSRDLEWYFFSMLDKKYRNGSKTNRATEMGYWKTTGKDREILNGSKVVGMKKTLVYHKGRAPRGERTNWVMHEYRLVDQDLDKTGVHQDAFVLCRIFQKSGSGPKNGEQYGAPFVEEEWEEEDDMTFVPDQEDLGSEDHVYVHMDDIDQKSENFVVYDAIPIPLNFIHGESSNNVETNYSDSINYIQQTGNYMDSGGYFEQPAESYEKDQKPIIRDRDGSLQNEGIGCGVQDKHSETLQSSDNIFGTDTSCYNDFPVESNYLIGEAFLDPNSNLLENDGLYLETNDLSSTQQDGFDFEDYLTFFDETFDPSQLMGNEDVFFDQEELFQEVETKELEKEETSRSKHVVEEKEKDEASCSKQVDADATEFEPDYKYPLLKKASHMLGAIPAPLANASEFPTKDAAIRLHAAQSSGSVHVTAGMITISDSNMGWSYGKNENLDLILSLGLVQGNTAPEKSGNSSAWAMLIFMCFWVLLLSVSFKVSILVSSR
The following text describes a protein:
Function:
Involved in a root UV-B sensing pathway and in the protection against the hypersensitivity to very low-fluence-rate (VLF) UV-B. RSU1 and RUS2 are probably both negative modulators of the same UV-B perception pathway, which when overstimulated in the roots causes a block to postgermination development. Required for polar auxin transport and to maintain the normal levels of PIN proteins in the root.
Miscellaneous:
MISCELLANEOUS: Several mutations in ASP2 (AC P46645), but not all, and any of the non-phosphorylated B6 vitamers can suppress the rus phenotype.
Subcellular Localization:
Plastid. Note=May be localized to the plastid as a consequence of its interaction with RUS1.
Sequence:
MQFLQEKVKLIKKEDPVMLKSPEDFPVYWFETSDSVSHRYQFQSDGHLSMKVVDDARPVPQKMVESFLNKFFPSGYPYSVNEGYLRYTQFRALQHFSSAALSVLSTQSLLFAAGLRPTPAQATVVSWILKDGMQHVGKLICSNLGARMDSEPKRWRILADVLYDLGTGLELVSPLCPHLFLEMAGLGNFAKGMATVAARATRLPIYSSFAKEGNLSDIFAKGEAISTLFNVAGIGAGIQLASTICSSMEGKLVVGSILSVVHVYSVVEQMRGVPINTLNPQRTALIVANFLKTGKVPSPPDLRFQEDLMFPERPIQDAGNVKVGRALHKAVKPSEVQRLKQVFVEEKFLLSHGKSWTDMVLEHDATGEDALRGWLVAAYVKSMTKIYNDPDDIILQDAYDKMNDVFNPFLSQVQAKGWYTDRFLDGTGTRFAW
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MSARKGYLLPSPKYTTIMSCSESPSGNAFLVDSLISGRTESGGGHYSGGALCVPHSTAAEVPYGLHSYGYFPGMTKRGEMGPQNVASASGAYMSNVEMWMDTQRSCRMEQEHPVGPQVAHCSFPQNIKEESTYCLYEQPKCPKASTAEDLTYSRLTTAGLGSSSCTATDGGGSGGSVPVPGYFRLSQTHAHSHKLYNTNGPQSNPSHSHFGLHPTAPARFLSPPTSTSARATDQETKDAEEPVSSGNADPQPRTALGAEEAQESSDGEISSGDETEENDKERPSKVIKGGAKTENMANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVHLTDRQVKIWFQNRRMKLKKMTRENRIRELTSNYGFS
The following text describes a protein:
Function:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
Subcellular Localization:
Nucleus.
Sequence:
MLRLKPAGIFKKVCEAIKDVTHNVYFDLTEKGLFMRFLHSSSSGAAWVEMLLLSDYLEDYRSDHKVSMPMNMNINDVYEIFDGDHDDYNGVIALMSITSGFLAFNFEDSIMFSNMHSADAPPLSVPPEYRDLANLEFHARVKMPALKFEHICAKLGLIDKTVRISVKEDTVEFLTYCFSIIASVVCKQTSIDKSGDELKCVEIQTIKPVSLTLDVKHLKLSTKATPLSNTTTLTLYPGKALVVEYNVGNIGYAKYHLPHQEDKTEEV
The following text describes a protein:
Function:
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Cytoplasm.
Sequence:
MMFPIRCFSCGNVIAEVFEEYKERILKGENPKDVLDDLGIKKYCCRRMFISYRIGEDGREIIDEIIAHDERYL
The following text describes a protein:
Function:
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Subcellular Localization:
Cytoplasm.
Sequence:
MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFADTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVVHEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPSLATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTNDTVLLLSSGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDALVAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFNGAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEENSAYSS
The following text describes a protein:
Function:
S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Also participates in regulatory T-cell differentiation together with CD69. Activates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme assembly by directly binding to NCF2/P67PHOX. The extracellular functions involve pro-inflammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its pro-inflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to pattern recognition receptors such as Toll-like receptor 4 (TLR4) and receptor for advanced glycation endproducts (AGER). Binding to TLR4 and AGER activates the MAP-kinase and NF-kappa-B signaling pathways resulting in the amplification of the pro-inflammatory cascade. Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn(2+) which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect; regulates cell survival via ITGAM/ITGB and TLR4 and a signaling mechanism involving MEK-ERK. Its role as an oxidant scavenger has a protective role in preventing exaggerated tissue damage by scavenging oxidants. The iNOS-S100A8/A9 transnitrosylase complex is proposed to direct selective inflammatory stimulus-dependent S-nitrosylation of multiple targets such as GAPDH, ANXA5, EZR, MSN and VIM by recognizing a [IL]-x-C-x-x-[DE] motif; S100A8 seems to contribute to S-nitrosylation site selectivity (By similarity).
Miscellaneous:
MISCELLANEOUS: Binds two calcium ions per molecule with an affinity similar to that of the S100 proteins.
Subcellular Localization:
Secreted. Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Note=Predominantly localized in the cytoplasm. Upon elevation of the intracellular calcium level, translocated from the cytoplasm to the cytoskeleton and the cell membrane. Upon neutrophil activation or endothelial adhesion of monocytes, is secreted via a microtubule-mediated, alternative pathway (By similarity).
Sequence:
MATELEKALSNVIEVYHNYSGIKGNHHALYRDDFRKMVTTECPQFVQNKNTESLFKELDVNSDNAINFEEFLVLVIRVGVAAHKDSHKE
The following text describes a protein:
Function:
Snake venom phospholipase A2 (PLA2) that inhibits the ADP- and collagen-induced human platelet aggregation (By similarity). Exhibits strong hydrolytic activities and prefers the anionic micelles (dPPC with deoxycholate) to the zwitterionic micelles (dPPC with Triton X-100). PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Subcellular Localization:
Secreted.
Sequence:
DLMQFETLIMKIAGRSGVWIYGSYGCYCG
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
METVEGRPAQYGVNVQQLRELMETRGQEAIQRIREEYGGIQDLCRKLYTSPTDGLSGSAADLEHRRQTFGPNSIPPKAPKTFLQLVWEALQDMTLIILQVAAFVSLILAFIEPEDHHENDHRGKPKEPGQSEAGWIEGVAILVSVVIVVLVTAFNDYTKERQFRGLQNRIEQEHKFAVIRGGEVNQIAVSEIVVGDICQVKYGDLLPADGIIIQSNDLKIDESTLTGESDHVKKGENIDPMLFSGTHVMEGSGKVLVSAVGVNSQAGIILTLLGAAHTENKEQKKKKKKKADEEAAMSGNSHMGNITANTHLEPARADSIVPASATHEEANPRKEKSVLQAKLTKLAIQIGYVGSTIAVLTVIILVVRHLIEVFVVEARPWRSSDTQHIVNCFIIGVTVLVVAVPEGLPLAVTLSLAYSVKPSEDGGQPKQVGNKTECALLGFVLDLGKDYQSVRDDVPEEMLHKVYTFNSVRKSMSTVVALDGGRGFRVYTKGASEIVLKKCKYLYGNGGQLESFGSDEQDRLSNDVQLQEEPDWEDEDNIIRDLTCLCVVGIEDPVRAEVPEAIRKCQRAGITVRMVTGDNVNTARSIALKCGIIKPGDDFLVLEGKELNRRIRDSSGEIQQALLDKVWPRLRVLARSSPQDKYNLVKGIIESKLHDNREVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNTVAVIVAFTGACAIRDSPLKAVQMLWVNLIMDTLASLALATEMPTTSLLVRKPYGRTKPLISRTMMKNILGHAIYQLTVIFVLLFLGPEIFDIDPGMGVRLSEHFTIIFNTFVMMTLFNEVNARKIHGERNIFEGLLTNPIFYSILIITAVAQVIIVQYGSMFFQTKALSLDQWLWCVFFGCGTLVWGQFVTTMPTKRIPKTFTWGSGPPDEMNATASLVEDGSSGSLSQDVKRTGQILWIRGLTRLQTQIRVVNAFRSNLDARNNPAYQTALLRKASAASPSGTGGFARPQLHSQPSQPQSSGSGFASPKEETAPSTASVAAAVPEPRAQSPQSPQQPQPPQQLQSPQQPAAPPLKEGDATSNHSVETAV
The following text describes a protein:
Function:
Counteracts the antiviral effects of host IFN-alpha/beta and key IFN-inducible proteins involved in viral RNA degradation suxh as host OAS1. Acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MVLGTAFVILALLGRSAFPVTVAPYDYMYDEDYYEYDYANYDPCDYIDDLEIHKAYEGEEVTMRCPLADCIIPSSPFSWFKDNKAYPWTDRPTERISLRGDQHEMLEIDSVQIAADNGTYRCEGFNGTEHLVGHISLHVKLSMTTLPPIILYPMDTSTSAYVEYRRLGQNVTFTCTAYLGVQQVIKQVYWLVNGTFINGKDRVKEGPHTEREDETGREFVNRTLVITDIQPEDYREYTCVAKNLFGNVTAQVQLTEGDDPNSSPVKEDLKEEMQQYRNGAAGGGAVLLMLCVLATVYYWKKLEIRLMIKDKFMPFEEGDTIEHMSDGDEDFQFHEQELHVTHFTMDIKLQQNARVLLSQEKGPEGVTYEIIIGSDNNTRSAICRHVHGMGESDQREVSALTPQILSRDEWKTFWVSFKEGIIEVGTPGEDPFLKWVEGEPLNVKYLGYMNGSRSKGKLRFSDLGQKEYDVFILYDIEQFEFVKNLLLPFLEKTCRCVVRIEHRDFTGGTELYDNYIEFIERSRRVLFVLSPNYVKNQWMKFASCVALDEMLREKARIVMIEYQPIKDQEDFETLKIFNEQVQKLMKAVTCIKWSEEAESRADHRFWRELRYNMPKKRVLSRKSSAWELLRQRSVVADSIVSNSIVRFGFRRQRSTLSDGVADYNRENKRSTFSDDNAIIAEDDHEEVHVTTPCLHFIDETRVCNERSSMLEKETVL
The following text describes a protein:
Function:
May function as iron donor in the assembly of iron-sulfur clusters.
Sequence:
MKWTDAQLIAEELYDRNPDLDPKTVRFTDLHKWICELENFDDDPNKSNESILEAILLKWLDEFE
The following text describes a protein:
Function:
Seems to promote the survival of visceral and proprioceptive sensory neurons.
Subcellular Localization:
Secreted.
Sequence:
FLQVNRGMSVLFYVTFLAFFRGLQASMDPRPVPEDSLNSLVIKLIQADILRNRLAKQAVDVKGEAPGESGTREPKAGFQPVVAADPDVLRQQRRYSSPRVLLSDSTPLGPPPLYLLEDFVETPGAPNRTSRRRRHAEHRSHRGEYSVCDSESLWVTDKSSAVDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT
The following text describes a protein:
Function:
Plays a role in transcription-coupled histone modification. Required for methylation of 'Lys-4' of histone H3. Plays a role in regulation of transcription. Required for maximal induction of heat-shock genes. Plays a role in Notch signaling in the wing margins.
Subcellular Localization:
Nucleus, nucleoplasm. Chromosome. Note=Co-localizes with Paf1 and RNA polymerase II on transcriptionally active sites on chromosomes.
Sequence:
MGKRRTQSLIDSNSSDSDSESETNLESDLMSLAKKRKKPQTAAKSSSRSDSDSDWANNKAGAPSSKKKKRQKPSRDSSSSESNWDDDSQDERQPARQSPAQTQQEHKPPEQASQPAQLSEQEEGEVSDSDSDKSKSNSSSSGSDSSSSSSSSDSEFDDGFDDDLMGDDEDRRRLNGLSEKERETEIYKRIEQREIMRTRWEIERKLKLARRGEKNQEKSKNKGERAKKKKEKREKKARKAREAQAPLPTQASTSTLLDVEPKPSNEVRSASPLSTPALNRDAASTSAAVASIMPDDAASSAGVSDYFDHKERSKERKKNVEANKTDDKRSNAMALLKAKREGKAKREEEEAKRMAEKDRDDDKEELDSVSGCKSAVKLKASEIYSDDSGSSDWDEEEKPAGKRSRSNSSKASSESEDEEKAPQRPVFITTREDLNKLRLSRYKMERFVNLPIFESTVLNCFVRISIGNNGQKPVYRVAEIVGVVETGKIYSLGTTRTNRGLRLKHGTQERVFRLEFISNQEFTENEFNKWNEVCQQSHVQMPTIDLIAIKQNDIKKALNYEFKDEDVDKIVEEKNRFRNRPTNYAMKKTCLMKERDAAMLRGDYDIAQDLGQQIDELENRASELDKRRSHTLNLISYINDRNRKKNVEDAEKAILEEARANKGLKISDPFTRRITQPRMGFKGAKKDEDDMQLAPLPPPPPGKKRPNEAGTSSASVRSTDSKDYSLYSLHDFDIDLDVPLPVNTNSVPKPASKPAETVSKRSLNLEDYKKKRGLI
The following text describes a protein:
Function:
May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MRRRGVAVAPARVGGRRRGEDSSDGTTGRRKGAGLGSPTQSQGQSAGSPGVGPEACLGRIVWSGPEASSERSXVGGGGAEAERAQASRPVLTGPRALTECELELLAFLLDEAPGAAGGLARARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTSSSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQQQPEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGRRPTEAS
The following text describes a protein:
Function:
Serine/threonine-protein acetyltransferase translocated into infected cells, which impairs host microtubule network and host immunity by mediating acetylation of target proteins. Blocks secretion in host cells by mediating acetylation of host tubulin, thereby impairing host microbubule network. Impairs host cell immunity by mediating acetylation of host TIFY/JAZ transcription repressors (Arabidopsis thaliana TIFY10B/JAZ2, TIFY11A/JAZ5, TIFY11B/JAZ6, TIFY5A/JAZ8, TIFY9/JAZ10 and TIFY3B/JAZ12), thereby activating host jasmonate signaling.
Subcellular Localization:
Secreted. Host cell membrane. Host cytoplasm, host cytoskeleton. Host nucleus. Note=Secreted via type III secretion system (T3SS).
Sequence:
MGNVCVGGSRMSHQVYSPDRADTPPRSERNTPDRRQRAAGDAERTQSMRLQQKINDLKPYVRHARGPIKAYGQAALDRASGKKTSVSFAELDATHLDAMVYIENQRNPGLNLKHFRDHKELIQALQSDGPSAFRAIFPQTCPETGQTLKHHVMADVRLHQGGAPTIIITEPAVIVGARYQQLQRHNLTLEDLSESGVPLSQVAIIETQAQKTSDDCVMYSLNYAIKAHKNAAQFDDIHHGLQHGTLSTESESRARTTLGALEASSSYSVMHEGAHAAFGADVLPVDFYKHGASLTQAKQLMKRPDGRMAGRVNSEGHSEAENLVQRNQAFRVKRRELLDDETPSNTQFSASIDGFRLQEIKRVLAEEQR
The following text describes a protein:
Function:
Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
Sequence:
MFGTATRDNATRVLLLGSGELGKEVAIECQRLGLEVIACDRYADAPAMQVAHRSHVFDMLDADALQQVIDLEKPHFVVPEIEAIATSKLVELEAQGLNVVPTANATRLTMNREGIRRLAAEELGLPTSAYQFADSYESFAAAVETIGLPCVCKPVMSSSGKGQSVIRTPEQIEAAWQYAQQGGRSGAGRVIVEGFVDFDYEITLLTVRAVDGVHFCAPIGHRQEDGDYRESWQPQVMSENAIKAAEYVAEQVVNALGGYGLFGVELFVKGDKVIFNEVSPRPHDTGMVTLISQELSEFALHVRAFTGLPIGQIVQYGPSASAAILGQGQSQNIQFNGLDDALSIPHTQVRLFGKPDIAGRRRLGVALSRGKTTQEATDRAIECAKAVKIHY
The following text describes a protein:
Function:
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MESPCRTITLEKNGTSLEPVHYSVQGKEILQIFKENFQKEDPVLFLDGTAGEGGHSFLFLKEFPNSRIILCDRDPIMLSRALTRLSDFSERVVSIQTNFSEINQKLLTSYGIDQTPQGILLDLGISTFHLFHSGRGFSFRESEPLDMRLNPNSGQSAEEILNIYPKDRLMNIFYTYGEERWSKKIAEVIVETRKQNSISTTFELANLVSKIIPRKFWPPGRHPATRIFQALRIEVNQELAHIENGLKLLLDLLRLGGVIQVISFHSLEDRIVKNSFRDYAKQNGFELLTKKPIFPSQEEIDENPASRSAKLRILRKTKSVDKKYRNKNFEEEEE
The following text describes a protein:
Function:
Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MNSDVDPLYTRLYHKYSMKYRRIIDKQYFDSPIFRLILHPGKRWFLCAFFLLVYFNRLIETQSYFVVSYMLGIQIIQSLLRYFTPLGLPDIEDEDEDVNIQLPQHNDDRPLIRSMPEISLWEQIIFALILSNFATFFQIFDLPVYWPFLFSYFILVIIITFKKYLKHMQKYGYSWGDFSKR
The following text describes a protein:
Function:
Required for mitoribosome formation and stability, and mitochondrial translation.
Subcellular Localization:
Mitochondrion.
Sequence:
MAPGPALPRLLGAGVRPRPQLLTRTTPGPARPSGRTLGSAAAPAVSEPEGDSGLNDRILREPLKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFMEPYIFGSRLDQDIIDLEQTAAHLQLALNFTAHVAYRQGIILFVGRNRQFSHLIENTARDCGEYAHTRYFKGGLLTNAPLLLGPMVRLPDLIIFLHTLNNVFEPHVAVRDAAKMNIPTVGIVDTNCNPTLITYPVPGNDDSPPSIQLFCRLFRTTINRAKEKRRQVEALYRLQGRAGAEGRSPASAPSPGA
The following text describes a protein:
Function:
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
Subcellular Localization:
Nucleus speckle. Cytoplasm. Nucleus.
Sequence:
MCSFLDVEVKDRFVEGDFGMSEMVKSNLANCSSRVKRPMNAFMVWSQTQRRKVALQNPKMHNSEISKQLGVTWKLLSDSEKRPFIDEAKRLRDKHKQVSDYKYQPRRKTKSFLKNVYNHKDHLTKATDQLIKTQHLKEDSTTIYENTMKCPEISSFYCAQESTYLDNWMNLPPEQENTEFWQGLFTNETETCRSLPHGQMDCNECRSI
The following text describes a protein:
Function:
Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. Required for the development of sheath cells in the hermaphrodite gonad and for the development of the male spicule, rays and gonad. In association with the zinc finger protein ztf-11, negatively regulates the expression of non-neuronal genes during neurogenesis.
Subcellular Localization:
Nucleus.
Sequence:
MSSAVRSPRKKAASDTSDPDRTSSPYSLRETSKVPSRYRNEELYLSPSRSIKRTGSPKKSPAKRLNGGRDSPSVNSLTRNSSLTMLAKAALDYESSSCALEYIFQPKEERRPPRRALALSPPPAPSNDLLAKDLEMIEMHQNLVAGLDDLDNPANMTNEAVEHRDTQSFFNMFSTDQERSAMMKQFKTYKNQTSEDVSTFMRANIKKLYNLLRYKKARQWVMCEFFYSAIDEQIFKEENEFATIIRESFPNLKNWNLTRIEWRSIRKLLGKPRRCSKVFFEEERMYLEEKRMKIRSVYEGSYLNDPSIDLKDLPAKLPRPMVVGNRVFARIRNPYDGIYSGIIDAVIPKGFRIIFDKPDIPPTLVSDTEILLDGKLDLLSIAYFIEQANSKLPSGVRPFVAAVRDSSHPHLVRDVLVSRKIERSGGPLMGPNDERLNGKNAEMVGNFPLKFLVNLVKLTKLIDIKKGLIRQLNELNADAEIQNMTSDKYSKAFQEKYAKTIIDLEHVNQNIDINMNGIQDHHMYFSSNDISTSNMKPEAVRQMCSQQAGRFVEHCNQGLNVENVHALTLIQSLTAVLLQVRTMGTQKISAVDLQSLGDAISEIRTAIHPRNVAFFQDYVEVHMKQFHTIMLESGALAGTVSNRK
The following text describes a protein:
Function:
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
Subcellular Localization:
Nucleus.
Sequence:
MDSGVPNLVATGKRRREGHPIDEDLKEVKETRQWYGSQRADDDVTEGFQNNVHYPGISMESLMRMQQIQQHQQQQQNSEAAVMSPVVPHLNMQQRVEAAAALQDLRGNVAFQQPQLQQHMKYGIQQQQQSISQMQKQGTKPDVCSLGDSNYQPHSPLSLPPPPYIRTPPLHSEADVHNGSPTSSSSGPYPNLPNLTAPPRSSQQCSAPIQLLEPESDSSYSSLMHISQSNLLAQSKAKSVQNGPLQTQQSLQSSLSGMSTQQLRGHSPQSGMAQQVDGVSGLHSTGHDLEVEISRQQAGQAVPNSGLQASGSHGVSTCTQGSLQNGNVHHQNGHGSPGLRQSGMQNGVAFQHNGHALSANGLHIGVQNTSIQQPGGHLLPNQLPQLGGASLPPQGRHSMPSSLHHQQGVNSAQNGMPNGSHNGMVHQQAVHSAPNGLPNASYSGMMHQQGGHRIQDGMLHSTGHISSMGPQNPGQNSAVIHQSVQGCSSGMQQQQQMVYPSLHRDIQQTPNNWYPSIRDSTTMSETQPSVSTSRLQTKVEAVAYSMNSPIHSFANQLGSQRGLPTALPQVNQVQNGYRDIMLDQDLKQEVCGSPSNMVGKVLPAHTDLQGRRFLQGNNFSAPSSSGGDINLSSTVMNGAFDDPRLLQRAFLCPQPKITRSYIKVYKLGSITRAVDVNRFKDYTELRCELARMFNLDGQLDPTVGWQLVFTDNEDDLLLVGDDPWDEFVRNVRGIRILTPAEVYFYTNEEKCTAAAYNSTGGSAPKPM
The following text describes a protein:
Function:
Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.
Sequence:
MTALYPWVPTSNAMYAFGRRLVNRFFPQVRNVYPLTFLDGPLPEEVPQSFLLHGRNDQPDPFKYMEDLFDRRTQSYVRQEQRHFTLVDSKFDFKHNKARLWAELDAKVVITSREGGFDKGEERIGDYIYFTRVVPGGDPNAIGFYRKRFGEVDLLAEELINPSALQQHFGYAHCNVGVCRVSQDGKYLAYTLSVGGGDRYICHVRSIDNASLFHVIRGRNIVSIEFGSDNQFYFTESNELNRPNAVIMQEIRPGVLPPPVELYRDDDEQFFVDVRKTKDNAYIVITSDSKVKCSALVLPASFPKIPREMQAFFPDARPVEIAGKGSWNWLEHYMGHFLMVVGDRGPNHRVVYAREEVVLKYGMDAEWKELVPHRDDVQIVDIDLFHDHIVLYESHFAFERINHIRIIKCGKGIDDTARRSRADDLVIHFPPLACVTPGLNKNFDQDSISFVYSSLCQPSKDCVFNFNSEMTSGKCRMCSPEAIFTQRQSEQFTPWDYMWPYTIYRDVCVSKDGTQVPITICHRRDAFVQEATDFEAQPNTPKHCFIYVYGSYGEVPSMHFQLAPYMWMLRRRWTVAFAHVRGGGELPNWAEQGRGEKKINAVHDFIACCEHMVNMGYTKPELMVAAGNSAGCVPIAAAMNMRGCGLFGNVLMRSPFLDVISTMVDPDLPLSLAEQDDWGDPLNSPKDYTRLLHYDPYHNINDRVTYPGMMVSVCLDDDRVPPWNSLKYVAKLRQQRRRKGVDPVEKPLILRVRSSGGHYIWNDTENLCEELSFLCSQLDLEGPGKVLNDMDIMTHMHNLTVTGAMDHDDQEKVFLKWDNWERERIDYHVKLHNFDWEPNFRKLKAEKQPFFWVPTDSELHQSKVDEMFRAKERDIRERGKSEAKTGSTGRAMGENKWASENGRK
The following text describes a protein:
Function:
DNA-binding protein that plays a critical role in nucleoid compaction, genome replication and DNA replication and transcription. Binds to both ssDNA and dsDNA with a binding site covering about 15 nucleotides. Displays DNA-supercoiling activity only when associated with the viral DNA topoisomerase 2.
Subcellular Localization:
Virion.
Sequence:
MAIQFELYKSPARKDEEDKELYHARVVNFQHIDTDYLAKEIQQATSLTEGDVKAVLESLSHFMGSRLREGERVHLDGIGYFQVKLNSLEPITSPKLKANQMKLKANIGFKADKKLRSSVSVVKVERSKLKLHSVPRSNEEIDRLLTAYFSNNQILTRSDFQGLCKLTLTTAARHIKRLKEEKKLQNINTRQSPVYVPMPGYYGKPEVEDTVK
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1). Cap1 modification is linked to higher levels of translation.
Sequence:
MFQSNQYDEYNKTNKSDEENESNENENENENENENRSEDGDQDSEDSFIYEEDDEEEEDTPKLSFGAKFLAKHGHIEGQGLGKEKDGRIDLIEVDRFQSTKGLGFAENDLPEFYRVTKHILEDEDVDFPSKQRFEWISCNSEGYNFWEGFPVDHTLVKFVANDSITDKPRRGHCSVELLMELDQHKNALDTLDPNRFYVARKKSNPYESIKGSIFINRAAVKMANIDKLADLLTPIIPVPGKPRDFIYFGDVCAGPGGFTEYVYWKKTRGGKIKGEEGLDLDDVVKGFGFTIKGQCDWNVEKFSKQIPIHNFVKEYGLDDTGNILKSENIRDFSSKVFYNTNGFGLQLFLADGGINTDGKESLQELMLQQLILCQILTMFETIGRGGNFVCKIFDTFTPFTIGLLYLVYQHFQSFSIVKPFTSRPLNSERYIICKNFLSYRPMNIIDFLHYINSLLNNNQTILELIEINSMDPNFLRYILESNELICLRQIKAFSLFKKYVEDIELPPIDQKEIRAKCLEEWGLPKETKYDIENYQKHKNRQKHHHNNHSNNNNNNNNSNNNNNNNNQHQHQHHQHQHHQNQHQNQYQHQNQHKKYNNNINNNSNNSSPNSSPNLTSSPNLNSPPNINNGNNHQNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNKNRRFISTKLVKNNSQFQQKPPPPHRHMSPLQIQQQFLLQQQKEQQLLQQPQKDQLHQLHQQQSQSALPDFSAANFMEALLKRKNDSQQ