lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Negative regulator of transcription elongation.
Sequence:
MADVRKSSRATKGQHPKAHELDQPVETKKKGKKGGKKTAVQEEEEVEVIRCVCGVTSTTDDDEAAWIACDNCAVWQHNVCVGVSPYEEDTPDKYLCEQCAPDAHKELLDGIARGEQPWIARQEKHEEEKAEQERQDAEEAARKKGKKGKKRSSDQKSDVTPANGKIQSPSVPAKKEPQKDSPAKSSNQKRKARDDELQDKEIIKESSSKVRKTMSRPTPRASPPSDLPSKITELEAEQQGQATLIKKGLLQAIPHAIEDRYYTLRPDDTIDAKAERLAIQIEEAVRNTHPNKSASIKQIRSIFSNLKQNQELCNGLLSQSLTPQALAVMTTDDMASNELKRETAIMKARADKQSIMITDDGPRIRRTHKGEEIIEGDSNPNEYSDIPMSAARRREMLDPNAGMGDRSRSRSPENEVEVPEIPEDYPSRDKGRTSSTPRTPLNIDTKQPALRKGSTQGSATGNFDINKVFSSVQSPHPSSNKQRGMDHYRRMSGNAPPANGPGDDPDVDKMLQDDNESPPYSPVEDNPDPDIVWRGTVSMDSVAKFSAYAKQVAGPDLSRNRMQTPWSELLHKDLKVHGRIDADKANEYLCGLRYSPPSDVVIINITPTSASSDFLDLYSYFHDKKRYGVLTNKGPGNVRDTYLVPVPPGPGNIPDFVVNLLEHNLPEERPEPSLLVTLVVRSGWEQPSRIQSFDGSADPHSPLTAGGIAQRQMSINHSGPAMSPSPIVPQGGFHPSTPIGKPDERYQQQNAEEQRRIAQAEGEAVALRILGEYARAPTVSFLMPQAYQMRDLEWQAIRSILERDEKAQNDLKHLSEVLARTGPA
The following text describes a protein:
Function:
Involved in the export of mRNA from the nucleus to the cytoplasm.
Subcellular Localization:
Nucleus.
Sequence:
MAAYHALAAMANNPPASSISIRGAAAAPARVVANALRGAGISARSQGMDVDGGGARGGDRPRGIERRKRSSGPLDQTGRHRPPQGGPPVDRPYGRSAPLRGTARRGARGGLSNPGRAPSGTPPGISALRQAPSKAEKDHAKSELSRKLSSAEMKAWLENRMIAPGVLDMSNLPNDEWIKSNGIFPPGHPHAPPTAGLVFWRLIDQTFQKTDKITIHTLSLANNNFSHLKQLEKLPIWLPDIRALDLSGNPINHISELDNILASGEKKGKANAGMGSLKSLVELKLNDCLFREKTLARPDGEAVYKHEILRRFPGLRILDGVSLERVIFPIERKPKVKHTEEEKAALIARPFSFPVEVRPDFFSEEAARNFAMAFCAKFFPCFDNNRTECLPAYAPNALISIAANTLTSRSAQQQVVLKSRLDRPNPVPFEPWINLPSRNFFRNATSIHQRMETLKTAADPAQLAEWWEKAVPRTEHPLTEASKWCFECWVLDSERGHVRLCLMIQGQFRELPSGTYRSFSRTFILVEAPEGSPAFNAGYPASILSDTMIVHSFFGTGAFDTTRPLGMNGVTIQPPSIPFTPSAVPAQAASGLGSGVNPSLSSISPGAGAGVGPGASPNGSSSSAAAAPDPTTQQSLISQISSRTGMNAQYAGMCLVQNGWDPEAAIKNFEEIKSSIPAEAFQ
The following text describes a protein:
Function:
Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Sequence:
MQLGVLTVTTSRTAATDASGGVLAEAFDGVFERVERGVVDDDVEAIQAAMLSWIREWDPDCILTTGGTGLDARDVTPEAVRGLLDREAPGIATMLTVQSLAKTPMAALSRFVAGVKRQTLIICLPGSPKACRECAEMLHPVLRHAIDTIRGRKRAVQKVHHTMQADTATTGNQDHTVSAPTPPAHTGCNCGRDAPVTSVQTSDYPVFYAAPPVPSETASERGSGAAARHRKSPYPMLPWSMARQRGLEALTPLRPVQRDVAAVALHEVLASPVTSTVNVPAYPASIKDGYAVRAADVDVESSASPVQLTVQGVSTAGAGWTGELPAGAAARISTGAPVPVGADAVVQVEDTRLIATKDGGAEEACIEILHPVSQGQDIRPPGCDVQAGATILDAGVTLGAAECALLRMCRVAMVDVVPRPTVCVFSTGDELIADPASADEQRADQVIDTNRPMLLDLLRAHGFDVVDGGILPDDREQLEGHLRTMCNQVDVMITSGGVSMGMPTVEGKGALLKSRRACVRADVRGCEAEQPSLASPKLLAWQARRTLSRT
The following text describes a protein:
Function:
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
Sequence:
MATKKVHRFSSEVDLQMSVCSLIAEKSTKAIADHGFFAVAFSGGSSAKIVCKGLVSLGLKLDFSKWRVFFCDERYASLNHPDSNYKLVKDNLLDVIKTKPECVISLDYSLPLEKAAVEYEKRLRELFPSEKEPPQLDMLLLGMGPDGHICSLFPGHPLLTESSKLVAAISDSPKPPPSRITLTYALLNEAHSAVFVATGSGKAEVVKRVLEGNESDPLPAARLKLTNGDTHWFVDDASASLLTKPGL
The following text describes a protein:
Function:
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport.
Sequence:
MGPLGREAWAQRLGAFRASPSAFLAGAEGEDLGRDLLSDLRSEKLSEQTKVSLLTLSLEYSDKLWPDAPAAEAAATSLLDTLVLLPTRPSALRRLLLLAATTALVSGDALGPTSGASCRLLPLLLGLASGRDLGRSFGTPSEQRHLQATACECLGELERCKPGLLAGALGMLRSLPGQTGPIQPVSLLLALVLHDTLVVQSRSGAGLQGLLVAEDFSTGSCPWDWTLAEEWDAHLKPQGPSWPTAGEEERGFPVLEPSPEDARELKAAVAQLLDTSYLLTPVAQAQLLWLLGWALRGLRGQPPVLFKPQLVRLLGTAQLTLLHSVLSLKAAFGEALFTAQDEALLLRRLTLGAQHPALPSPTHLFYLHCILSFPENCPLGPEGEEAAPLLLGPQLCRGLMPSLLHDPTVLLARLHLLCLLCADDEEEEKDQTQGPQWFLQEVLAGLQQRAALDGGPRALATLCFQASYLVTNCLTRHSTVQTFLIRGLAQLYRARPSLAPHFVDLLDQVSPELREPLREVLLQEAVARPGESEALCWHLQMLAKVAEGATQSTTLSFLQAAAVHCTDWGLHQALLRVCRALLRTGGGDGLANLLQELARQLENADGRDHARLYYVLLSHLSSSKLGMALGPSLAAPALASSLMAENQGFSSALMVQETSAPIQLSVGPQQAKGPLPVLCLQVQALDAPVYSLELRFRVEGQLYEPLEAVHIPCLRPGQPAHPLYLLLQPRCPAPARLHVRALYSTSAGLTCHARLPPLSVNFADLFLPFPRLPKGSELRFFDELWNSCLPKGVESRVWCPLGQQGLEALVSQYLEPFVVLAQPPTTYLIAIRLPPASMLLLRLEKAQVDGVPVALRTDDWAVLPLVGDYLRGLAAH
The following text describes a protein:
Function:
RNA-binding protein that acts as a translational repressor.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MKCLEGLHLQQRPSKFSVSLAPEEGLVCAFQLEEEKENEDECVCSDQAPEVKEEGCGLGDPAIVSAFQNTQVPQQRGLHSSHRVKVSGALGMSSASLHFMWQSVFPRASSPAHHFGPQQPSPDPFLFYSPLTPWPPKLSLPSHLTQLHPQHQQILQQQQRWRRRRSPTARSVPAQKPWSREPAASDAYANLMTRKEKDWVIRVQMVQLQSENPRLDDYYYQKYYQKLEKRQADKELLGQKTRAESLKLVTPYIQKPEVYESVVRIEGSLGQVAVSTCFSPRRAIDAVSHGTQEQDTGAASSQRLRVLSQIEKMFLQLLKIEEGQNDGLPQLYHTREQSSQVEKLFQALKTQEQNNLEEAADNLLQVLSVRKGKVLVARLLPFLPPDQAVSLLLYITYHLPLLIQRDMADQGLHMLFKPLGKYISHLTFHQLLHAMQGLMLLSPGSSERPVSVVLQNQFGISLLYALLSHGEQLVSLDPSLRSSSDCATWTDLVILIAWEIAQLPAASLAEPLAFPRNLLPCSAITWTSN
The following text describes a protein:
Function:
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidation and isomerization of cholesterol, pregnenolone, and dehydroepiandrosterone (DHEA) into cholest-4-en-3-one, progesterone, and androsterone, respectively.
Subcellular Localization:
Cytoplasm.
Sequence:
MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKTAATVKP
The following text describes a protein:
Function:
Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
Subcellular Localization:
Cytoplasm.
Sequence:
MRTNWQVCSLVVQAKSQNIAAIGTQLNTLPGCEVALSDVESGQLIVVAEADQSETLMQTIESVRNVEGVLAVSLVYHQQDEQGEETP
The following text describes a protein:
Function:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Sequence:
MSAAHKNLLAVWAKEPKDLVAVEKALNELTKVLSASSDLNDKQSALASKDLYEISVLLAILKHDFETFDDYINQMHTYYTMAPENSENKHLMTGLHLMFLLAANRLSDFHMLLEQIPQKEQTSNAYISTPVRIEQSLMEGAYNKVVLTEKNIPSPFYTIFIRIMLDTIRREIATSIEKSFKVLTAKDATVMLLFDNDEQMKKFGQERKWHLDGERYVFEIEVAQEKPVNLDTVRVATQTLFYAKQLEQIV
The following text describes a protein:
Function:
Late secretory t-SNARE protein required for secretion and proper cytokinesis. Plays an important role in the secretion of virulence-associated extracellular enzymes and vesicle-mediated polarized hyphal growth.
Subcellular Localization:
Membrane; Single-pass type IV membrane protein.
Sequence:
MSNPYQNSQNGYQQNNSYELNNYPNKQYSSSNEDDFVQFMNEIQDINSQLDNYSNIINLIDNKQKNFLHGLDLNDEDTDYDSKQIENLVNEAQSLQLDLKNRIKNVQTQAVHSRDQTKVDQAETCRKRFLDLIQDYRLVEARNKESTKEQAARQYQIIKPDATDEEIKAVVEDGSQQYFQQALMQSNRRGEARSVLNEVQVRHRELLKLEKTMAELTQLFHDMEELVIEQDQPIQQIEEQVGTAQHDIEQGVGHTNKAVKSAKSARKKKLWCFFICLLIVIILAVILGAYFGTRK
The following text describes a protein:
Function:
May be involved in cell wall biosynthesis.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Sequence:
MQQRKAPKASAEGVTEQEASPAAVLPRTATARDLLEAEEAPDQCSMTPRKKNKKRQTGAGERRCRPVLNLLLVAFVVAVLLAVVLLADGGRVPAVWIAAARAQLRRGSGHAWLPYARNAPDKLLGGLLADGVDGETCRSRHESSAYRRSTPRRPSPYLVAKLRRHEELQRRCGPGSDAYSRAVQQLSAGRSAVDAECKYVVSVCNRGLGNRILAAASAFLYTLLTDRVLLVYRGNGMGDLFCEPFPGATWLLPPDFPVAGLANITVDAAETYGNMLKNKVLTADSKEPVQVPALAYAYLEHDYGDGDKRFFCDDDQRLMSNIQWLVARMDTYSVPGLFQVPSFAEELAALFPESDAVFHHLGRYLFHPADHVWGLVSRYYRAYLARAEQLVGVQVRVFDSEQGKSPHVLRQITSCVWKEKLLPEVLAAGEPVITPATGGISRTVLIASLRPWFYERIKSMYWEQPTASGEDVGVHQPSHEEYQQFGRRSHDTKAWAEMYLLSLCDVLVTSGWSTFGYVAQGLAGVTPWVMYRPLNFSETPDPPCGRDVSMEPCFHTPPMYDCKLKHTADTARSVPHIRRCEDVKWGLKLVGPK
The following text describes a protein:
Function:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
Subcellular Localization:
Synapse, synaptosome.
Sequence:
MATEEDMRDELYNMQQKIDQTTDDSLESTRRMLQMAEESQDVGIKTLVMLDEQGEQLDRVEEGLDRINEDMRQAERNLTNLEKCCGLCVCPWKKWRSFEKNSSYQQAFKGGEDGKIVTSQPVRMSDDRNGPQVSGDYITRVTNDAREDEMNENLTQVGGIIGNLKHMAMDMGNELDMQNTQLDRIETKADSNVDRIQLADKRANKVLRKQ
The following text describes a protein:
Function:
Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by G.sulfurreducens.
Sequence:
MKTQIEQAREGIITPQMAAVAAEEHVSPEYVCRMVAEGKVVIPWNHVRAPKAVGIGKGLRTKVNASIGTSSDIVDYEAEVRKARAAQESGADTLMELSVGGDLDRVRREVIAAVDLPVGNVPLYQAFCEAARKYGDPNRLDPEMLFDLIERQCADGMAFMAVHCGINLYTIERLRRQGYRYGGLVSKGGVSMVGWMMANGRENPLYEQFDRVVGILKKYDTVLSLGNGLRAGAIHDSSDRAQIQELLINCELAEMGREMGCQMLVEGPGHVPLDEVEGNIQLQKRMSGGAPYYMLGPISTDVAPGFDHITAAIGAAQSSRFGADLICYITPAEHLALPNEEDVRQGVKAARVAAYIGDMNKYPEKGRERDREMSKARRDLDWQRQFELALYPEDARAIRASRTPEDEATCTMCGDFCASRGAGRLFAGDLRGDKV
The following text describes a protein:
Function:
Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS).
Sequence:
MPICEFSATSKSRKIDVHAHVLPKNIPDFQEKFGYPGFVRLDHKEDGTTHMVKDGKLFRVVEPNCFDTETRIADMNRANVNVQCLSTVPVMFSYWAKPADTEIVARFVNDDLLAECQKFPDRLVPLGTLPMNDVQRAVEIFGKRIFFFEIWSPAKKSPEEVKRCVSMGIKGFEVGSHVAEKSLDHRDFWPLYKLTESFKLSTIMPGFCEFFENWGLTTKTPGICEELSVVLFVHPWDMHMWDGRLDKYWMPWLVGMPSETAQAICSVLMGNILVLFPKLKLCFAHGGGAYPQIRGRVSHGWNVRPDLCAGKCKVAPNKLDGLLWTDSLVHDPKALELLINTVGKEHIVLGTDYPFPLGELEVGRVVEEYKPFSAKDREDLLWKNAVKMLDIDENLLFNKDF
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ester bond in chlorophyll to yield chlorophyllide and phytol.
Miscellaneous:
MISCELLANEOUS: It has been proposed that CaCLH0 is transported to vacuole via the endoplasmic reticulum where it might be glycosylated.
Sequence:
MAKLLLLIFGVFIFVNSQAQTFPTILEKHNSEKITDVFHKGNFQVTNNPIRVKRYEFSAPEPLIIISPKEAGVYPVLLFIHGTMLSNEDYSLFFNYIASHGFIVVAPKLFRLFPPKLPSQQDEIDMAASVANWMPLYLQVVLQRYVTGVEGDLEKLAISGHSRGGKSAFALALGFSNIKLDVTFSALIGVDPVAGRSVDDRTLPHVLTYKPNSFNLSIPVTVIGSGLGNHTISCAPNHVSHQQFYDECKENSSHFVITKYGHMDMLNEFRLSPIAVTMSLMCAQSFRPKATMRRTLGGIMVAFLNAYFRDDGRQYYAIIANRSLAPTNLFAEKKGFNFGFATTYAQL
The following text describes a protein:
Function:
Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow. Regulates neurite outgrowth through the inhibition of RhoA/Rho kinase signaling.
Subcellular Localization:
Cleavage furrow. Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MLCGRWRSSRRRPEEPPVPAQVAAPVALPSPPAPPDGGTKRPGLRALKKMGLTEDEDVRAMLRGSRFRKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAPSQHIFFLQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFRGRRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMTQRERLDHWIHTYLHRADSDQDSKMSFKEIKSLLRMVNVDMNDMYAYRLFKECDHSNNERLEGTEIEEFLRRLLKRPELEEIFYKYSGEDHVLSAPELREFLEDQGEDGATLAHAQHLIQTYELNETAKQHELMTLDGFMMYLLSPNGAALDPAHMCVFQDMDQPLAHYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLRTILGDMLVTQALDSQNPEELPSPEQLKGRVLVKGKKLPAVRSEDGRILSDREEEEEEEEEEEEVEAAEQRRLAKQISPELSALAVYCCATRLRNLRPAPTLPQPCQVSSLSERKAKKLIREAGNSFVRHNARQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLINGQCGYVLKPACLRQPDTTFDPECPGPPRTTLTIQVLTAQQLPKLNAEKPNSIVDPLVRVEIHGVPADCARKETNYVLNNGFNPRWGQTLQFQLRAPELVLVRFVVEDYDTTSPNDFVGQFTLPLNSLKQGYRHIHLLSKDGASLSPATLFVHIRIQCS
The following text describes a protein:
Function:
Serine/threonine-protein kinase involved in the regulation of auxin signaling. Acts as a positive regulator of cellular auxin efflux and regulates organ development by enhancing PIN-mediated polar auxin transport. Phosphorylates conserved serine residues in the PIN auxin efflux carriers. Phosphorylation of PIN proteins is required and sufficient for apical-basal PIN polarity that enables directional intercellular auxin fluxes, which mediate differential growth, tissue patterning and organogenesis. Acts as a suppressor of root waving.
Miscellaneous:
MISCELLANEOUS: Over-expression of WAG1 induces a basal-to-apical shift in PIN1, PIN2 and PIN4 localization, resulting in the loss of auxin gradients and strong defects in embryo and seedling roots.
Subcellular Localization:
Cytoplasm, cytosol. Note=Targeted to the cell periphery.
Sequence:
MEDDGYYLDTDLDLSFTSTATDRTFTSSSARSSLARSSLTLSFNDRLSTATTPSTTTSSAATTLHHRRYDPHWTSIRAATTLSSDGRLHLRHFKLVRHLGTGNLGRVFLCHLRDCPNPTGFALKVIDRDVLTAKKISHVETEAEILSLLDHPFLPTLYARIDASHYTCLLIDYCPNGDLHSLLRKQPNNRLPISPVRFFAAEVLVALEYLHALGIVYRDLKPENILIREDGHIMLSDFDLCFKADVVPTFRSRRFRRTSSSPRKTRRGGGCFSTEVEYEREEIVAEFAAEPVTAFSKSCVGTHEYLAPELVAGNGHGSGVDWWAFGIFLYEMLYGTTPFKGGTKEQTLRNIVSNDDVAFTLEEEGMVEAKDLIEKLLVKDPRKRLGCARGAQDIKRHEFFEGIKWPLIRNYKPPEIRGLVKKTKAHAGHVTAAVTPRRNKWLWWALSHLLRSKSLSKSSSKIQSNNNYYHYVGKKL
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Sequence:
MSQQQSLFSFYSRGGAAAKPKANSHRSDFSVVKHEQREVAGCREGYHLEQGRKKLDSASQGQSLSTQNVLQSIEERFVRREKAVKPIGIVTTESRETSLDPTGNKRIRETEEKLVCPVPSIAQNQNLQKRRKLLEALGADDGVETTGAWAEARAKFEWMTPSKIRDAEKRRPCHPAYDERTLHIPHDVFHKFSASQKQYWTTKCKYMDTLLFFKVGKFYELYELDAEVGHKELDWKLTVSGVGKCRQVGCPESGIDDAIQKLVSRGYKVGRMEQIETAEQARAKRGDKAMVQRELVQIITPSTVMDGNIKPEAVHLLALKEEVREATNPIPGKADKLVIAIGFAFVDAAAGRFYVGSLSDDTSLINLKTLLTQVAPQEVLYESGGISKESLRALRRLSAPGLLPVTLTPLQPSLEFMEAGDAIRMLRSNRYFTDSSDNNWHTEGDDSWPTALKLSADIPLATSALGALVSHLTRMKCDGELLPNGFLCPYEVFKGSLRLDGQTVSNLELLENRDDGGKAGTLFNYLDSCVTGFGKRLLRRWICHPLRNIGDIHYRLDAVDELNSWPEMTCSLRAGLRKLPDLERLIARIRNLSFSPLAGIPTAAKKVHQRKLKAFCSTVLGVRAAGELLLLINNLRSDGNIELKSKFLQAAAALPYPKPVEACLKELELGIDASCKTCRLSKSQEGNYVDDDEQEDEWEARRLSQLIDMFNEHTSFWVKLVDTLGQLDVLISFASTISAANGPTCRPQLVPSPCLPKGGSVLHIEGLWHPYASGGQDGAFVPNDIELGPVNASRIAPHAMLLTGPNMGGKSTLLRATCLAVIMAQLGCYVPGEACKLSPVDTIFTRLGASDRIMAGESTFMVECNEAASVLHHATSDSLVILDELGRGTSTFDGYAIAYAVFHRLVNSLDCRLIFATHYHSLTEEFATNRDVSLRHMACSFQSRSSGKGGQNSSEKSDCDLDKELVFLYKLTEGASPKSFGLQVALRAGIPGSVVKAAHTAANAMQESLPETFVSGENSSGCRSNQRQLLQTILQSVNHKIGVEACREKNISYDLLRSAWQSLQCKAGSVESSVHSGAATAIRNTQTANR
The following text describes a protein:
Function:
Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes. Controls primarily the late process of sporulation including trehalose biogenesis. The complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes. The vosA-velB complex binds to the beta-glucan synthase fksA gene promoter in asexual spores for repression.
Subcellular Localization:
Nucleus. Note=Localizes in the nucleus of mature conidia.
Domain:
The N-terminal velvet domain contains a NF-kappa-B-like fold and is involved in DNA-binding.
Sequence:
MSAANYPDPSLPRPSTSDDFELIVRQNPNRARVAGGKEKERKPVDPPPIVQIRVREEGTYLAQHYLQSPYFFMSCSLYDAQEDAPASIPPSTALTGTLVSSLHRLKDVDNTDGGFFVWGDLSIKVEGDFRLKFSLFEMRKTDVVFLKSIVSERFTVSPPKSFPGMAESTFLSRSFADQGVKLRIRKEPRTLIKRTAPRPEEYPQAAIPRSPSDRTAMQIPGSSYPAPPYQPTSRDYSYYAPVKRQRTSVDYGARGMYDADGRMRQMETYPQTATLYGQPGGYPTPMMGYPSGHGGVPDYAMSYGLPPSAQVPQMQDPAAQSRSSQQATMQSLGMVNPPGTPTPDSARAMMQQAYPRPQYSASTAVLPPLQQSRNYPQGTNGATRGYYEQSPQATPILPSQPLGTSEAERYGVPPGHTGYDHTGSANGTPR
The following text describes a protein:
Function:
Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The action of SPO11 is important in setting off a regulatory chain of events encompassing 5' to 3' resection. When there are no SPO11-DSBs, resection of a site specific VDE-DSB takes place but it is faster than in wild-type meiosis and increases the risk of uncovering flanking homology.
Subcellular Localization:
Nucleus. Chromosome.
Sequence:
MALEGLRKKYKTRQELVKALTPKRRSIHLNSNGHSNGTPCSNADVLAHIKHFLSLAANSLEQHQQPISIVFQNKKKKGDTSSPDIHTTLDFPLNGPHLCTHQFKLKRCAILLNLLKVVMEKLPLGKNTTVRDIFYSNVELFQRQANVVQWLDVIRFNFKLSPRKSLNIIPAQKGLVYSPFPIDIYDNILTCENEPKMQKQTIFPGKPCLIPFFQDDAVIKLGTTSMCNIVIVEKEAVFTKLVNNYHKLSTNTMLITGKGFPDFLTRLFLKKLEQYCSKLISDCSIFTDADPYGISIALNYTHSNERNAYICTMANYKGIRITQVLAQNNEVHNKSIQLLSLNQRDYSLAKNLIASLTANSWDIATSPLKNVIIECQREIFFQKKAEMNEIDARIFEYK
The following text describes a protein:
Function:
Methylates ribosomal protein L11.
Subcellular Localization:
Cytoplasm.
Sequence:
MMKIKRFVYSLPEEEFYELVYSQNLSVEVLERKEIEVIFASYKEIEGLTPEKVEEVKEDWENWKEKFKPIEVEDFVIIPSWKKPVIVKPGLAFGTGLHPTTQLCIKALKKYLKEGMTVLDVGTGSGILAIVSALLGAKRVVGIDIDEKAVNECRENAELNKVKVECFRAEPKDVNESFDLVVANLEIHIFERVLKDILPKFKKIGIFSGLYKEKDLKRFEELLGGLKVKEVFEKENWYAVVVEKG
The following text describes a protein:
Function:
Transcriptional repressor involved in organogenesis. Plays an essential role in ureteric bud invasion during kidney development.
Subcellular Localization:
Nucleus.
Sequence:
MSRRKQAKPQYVLLDHTMEIEPSPTCDVHICEQCCAEFSSITELYQHQKDCSKDQLVLIVSENESLDSPPSALTVNSPFFNTEEHSDGVTNNDSTEDLGDSSNEGTLLEVEEPLDVLEILGIDKKSNKCSNDGLSFAYSASLPQDIALLELCKLSAINSNVFIENLENTKVAVAQFSQETPLKTSCINASNAKKVDLGLIEQLLALQQQQMQQLKLIEEIRAQIMLLATQNSKTPLTTNSNGLSQTRSLIKLSSQLSEQLTAAAGLAENLAANAKQSTHVIPQNQDGLRGEKEDSKVTSKIRDDSLPMKLDIDQSGNQSLHDSKVTNKVDGGANLKTPSPSPASDGIVNKLELPHKPNSFNISANSLPSIGAIVEDLNALTALAQHRKAKPVNVSLCEHKRPSEDCIFKHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNICGNRFSTRGNLKVHFQRHKEKYPNVLMNPYPVPEHLDNVLTSTGIPYGMSVPQEKPPLSWLDSKPLVGNSIGFMLSSSLPGLPVIIKKEEEGVSITKPHSPVVSELTKRINGHQEGFVCSPPIISNEKFQEVNQRLSVSTLLRSSREGSREDIAINTSVNTGLITKLKSEQLEAKFLLGSLPNPLGASETAKLEQLVENIDKKYTDPNECGICHRVLSCQSALKMHFRTHTGERPFKCRVCGRAFTTKGNLKTHYSIHRSMPPLRIQNSCPICQEKFTNAMVLQQHIHMHMGGHIPNVPMHDSSEELMDQDLVESMDTFPNEDTDTMQGASDLKNPDSLTESECSSPASSVFARSESQIKVTNVENLENTSKLVIQDGSIEGDCLTQGLASQNIEHESLRRRIPSESTASWSPSSPKGYTTIDPKSAESNNSNLTVSRLLDGASGEVQKDTLTMVFPYINQGSLKSNVCDICNKMFACQSALDIHYRSHTKERPFICTACNKGFSTKGNLKQHMLTHQMRELPSQLFEPANKILVLPPNHLLPSVETNIPPKRIEHNGFIKKDLKDSPSCIFSSSASTMPVLPTPTLRRTAKQHFCQTCGKTFSSSSALQIHERTHTGEKPFACNICGRAFTTKGNLKVHMGTHMWSSSPARRGRKLSVDGPYITSNSERFQDGHPKDVVAKVRNGDSVGLWSQHHNSSGLRTNEIPVIQNGAIPHLSISAGHLEKLQLNRALPWLERLSENGAAFHFRQLVEDHKTTLMD
The following text describes a protein:
Function:
Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MPLLNRYIRNAIITATALVMLVLLGIEMFMEFIGQLSQIGSVHYGLGQAFLYVLTQLPSDLYQLFPMAGFLGCLIGLGRLASSSELMVMRTAGVSIAGVTWAVVKAALLMMVVMTFIGEVIAPQLEASGEETKLTELSKAVGYKALGDVWLHGAQSFIHIGSVDAKNKISEVSQFFINNKHQLLSAVYAPKGEYVKGHWILYNVKQTQFTPNRTTEKKIAKFPLTIVFNPDHLQQGRKMVDRQSIVGLYHTIRYHQQAGLQTSRYVFAFWQRFIQPLTTVVMICLGVPFIFGSLRQASMGLRILTGIVIGFAFYMLNQFFGPFAMVYQIPPIFAALMPTVLFAVGCVILLRYSRR
The following text describes a protein:
Function:
Methyltransferase catalyzing 4-O-methylation of glucuronic acid side chains on xylan.
Subcellular Localization:
Golgi apparatus membrane; Single-pass membrane protein.
Sequence:
MRNKSQSFISSKLIFICCSILVLFILFLKRASFSSNSTATIRDEYHQKSKCPSTPQQCTKLPTSLSDALVHYVTSEITPQQTFDEVSVSKRVLDKKSPCNFLVFGLGHDSLMWASLNHGGRTLFLEEDEAWIETVTKKFPNLESYHVVYDTKVKDSNKLMELKRTEDCKAVSDPRDSKCALSLKGFPADVYETQWDVIMVDAPTGYHDEAPGRMSAIYTAGLLARNRYDGGETDVFVHDINRPVEDEFSVAFLCGGYMKEQQGRLRHFNIPSHRASFGTPFCPADISRRF
The following text describes a protein:
Function:
May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).
Sequence:
MVRSDWRAQEIRRVMTFTGSKEKTARDALEKFDWNVEVAIDHILNTPQVDLSGASKVFDKYRNADSDEIDLDGTIQYITDLGLSLEEPTVLAVAMTAGSPSVGTFTRKPFVEGWAAIGGDTLPAQQKLCRSFAESMTSLNADFQKIYKFTYGFLLQEGQRVLPQETAVDYWRLLLTGKYEHLDKWLSFVTEKYKRNISRDAWNMLYEFMLFQAKDPSLESYDEDGAWPSVIDEYVEFLKE
The following text describes a protein:
Function:
Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SEC65 is required for SRP integrity.
Subcellular Localization:
Cytoplasm.
Sequence:
MPRLEEIDDFNDIDDLDMELAELDPSLRTPIAPKITPKVVRSQDQENPAFLPGTNNNSNSNNNSSNEKEQLSFINPKTGKVERSEAISKKDLEEVKRFQVLYPCYFDINRSHKEGRRVPKELAVENPLAKTMADAVRELGILCIFEGEKCHPQDFGNPGRIRVLFKENGQLIGAATKFKGGKRQLMKAVGEYMKRHPTTIESLREIPYGPDFDNIEFKKIPRVKGFKMNEIVPLHSPFLMGHPMTKSVYETPKITAAEKSFKPPKNKYKVVRR
The following text describes a protein:
Function:
Has a role in meiosis and sporulation.
Sequence:
MTTNPDIVKQTKNEIHQVTSRVQEKLDSKSTNAVEQNNNSSQASVTKDNKKKAAKRAKKKAAKKKKQSAAASASSTPVEEAQHAQEEQQEQTILQEPGFTQTIVEKDADQVDEPLEPIASSALGTVEPPTDNKPSASTSTAVPTTEARNTSITEPANSPSSSSSSASTKSTATTQSADYVVAEHFAPQRNDEQLGNSPASITSKPATTSAAQPSSKVEENMAKATSQPITTAEKEIPELKPIEPEAIMISKEINTTHDQAAATTTAAVASASTTATAESHAVADGIMNDNVLESIGENVQQETVFEDASDIPHADVIPHTTTVTVEEESPIALGQGGVTHEATTSARASASGIPGAFEEVQQTVQEDLPHPTAETVEIARFAEQPVRAQQPEQYESSVVQEATETVTDVGKGVSSTVKNEVNVPSTIPTESENPVAVGGTTAEHPVQEAVTAPTETAHDFSKETTTASKRVSKHDKASAEKHKVARKPSSTGQEPTTPSTPAKSAQSSKHARRPSKQASAPSSPGTTSAAVPGGKKSAIEAAAPIPTSADTVESKHAAGSGSATTIPSPGSATTKPTPGSATTKPTPVSATEEHAAGTTKPAPAAGATATAENETADGKAQTATDGEAAPKKSWFKRMKKSFGKLFH
The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MSRVNLIEKNSDSELVGQGEEADFKNLFKLDNIRDGVSLGLVQQLGGEQGLAKIFQVDLKRGVQDEEQVSTLRNRYGANLPIVKELTPLWKLIVECLGDTMLQILIVAAIVSTVLGIIEGEGGWYEGLTIFLAIFLIIGITAGNNYAKERQFAKLQSKLDEGHVQVKRGGNITTISNKDIVVGDVLLFQLGDIFNVDGLYLSGSEVKIDESAMTGESDEMLKAPLDVCLKDQKGKSPFLMSGTKVNEGTGVMLVLQVGEKTVQNEMKRLGESDSTPTPLQVKLEGVAETIGKVGVIVAILTFVILLVRLFIEYAQNDEQTFWEQFWHLDCLQKILKFFMIGVTIIVVAVPEGLPLAVTITLAFSVNKMKDEQNLVKTLASCEIMGGVNNICSDKTGTLTMNTMQVNSIFCYGSNYKDYQLLQIKNLEKDYLDLLAASNLYNSSAYPKRGINGKFEQIGNKTECALIEFCDMLGYQLSSYRPSDNILRVIPLNSKRKMMISLVHHNNKIYLFTKGAPEMVLKKCSKFINSNGEEAKLTSQDTNNIQALRTLGNAYKILNYHLEYDFDSIPEEYLLTDLTLINIAGIKDPVRPDVPSAIQQCYRSGIIVRMAKAIARDCKILGPDSDLHEYEAMEGSQFRQLTGVEVQEVKDLLKFQEIVVHLKVLARATPEDKFILATGLKQLDNVIAVTGDGTNDAPALRKADVGFAMGITGTDVCKDAADIILLDDNFSSIITACKWGRNIYNCIRKFIQFQLTVNVVALFMSVLGAAVTKEAPLTSIQMLWVNLIMDTFASLALATEPPSDRLLNRKPYGKRESIVNSIMYRTVIGASIYQIAILCLILFIPDRIFDFDDSLDKEYEDRPIQRLTMFFQTFVLMQICNSISCRKLDEVSLNPFSGLFNNSLFWLINLIEVAVQYLLILFGDKFAVVCELTVWQHIFCWIFALGGMIVAIFVRTLPSRWFNGINIFAEEGIEEENLDETIASKLRRKSSIRIGSVYDENHENKRSVQKRLSVFKE
The following text describes a protein:
Function:
Component of the histone H2B ubiquitin ligase complex (HULC) which plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.
Subcellular Localization:
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Sequence:
MSSRRNDYHYDGNDHQYRSPLKSNVDQNSFYESSYRSRQSYHQRTKTPRSSYDSPSSSTNSKEHNSPYHYRVPSNNSTRASFGAASTDTNVELPKINLPDSSLSSKLQSCKSACENSSQSLLNVEQQYAQQVHFWEKIRTDIYREGLRSDAAVKSLNDFVNNVSF