lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in cytokinesis and septation where it has a role in the localization of F-actin.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MFWNKVLVRKCKNRKKIVQDAVHGYNPFNKIAGGGKKSAISKTESSNKIQDSMKRCIKSQAGLTALDHLKCSYIFSILDNLNIISAQAKCEVDMVNNLQNSSLYKEDETFKNLIDLWAQAARQMDVQTNELNSISNKVVVEPMKKFSTIFPSLQMAMRKREQSLQEFTKCQEKVEKYLKRERTGPNAVKLENSRKSCAIAKAEFDHLNSLLMDEVPKLYEGRIAYFQPSLQALVNAQTTYYNEAEVIYSQLCKQLKEGYRTDKKEDEDADGGFSLDPDELKLTIQQKLSEIRSLSIAVDDQIK
The following text describes a protein:
Function:
Component of the post-replicative DNA mismatch repair system (MMR).
Sequence:
MKQTTLQRFLTSSQKKNQPTGLNNTKVSNDNSLIEEKKIEIQYIKPAASFQKEEGVKVIKEQVVENVQEKPQQLSRLKRNSIVDSEDEQEKKEVDQNELKIDKFTFVGSQEKNKEKKSLAVFIKQDNTKNNTKTSQKQKKSECDKSGKPLKQSAKLEDEEIDYSQENKQGNLDFRHPTDKINVYEEFDDVTPKWASIGLSRDKSGKLHGTSDADPTTLLIPQSDFNKLTKCMQQYWKYKSENFDKIIFFKLGKFYELFYEDAYIGNKYLDLNWMGRKMHTGFPEKAVHKYKALLLEYGYKVVIVDQTETPEQMNQRVTQNKKTGQGNTDKIVQRQISEILTKGTYLYEEGESQMNLDEKVLLVIRKKIISNAIEEYGIAILERQTNTISLAFIENRDKNYESLKTLLLHMRPVETVIDQHNLPSHDPITKMIGGSVIQSVISHLTASQDNWDEKKALFRLEQYYQNEFPPAIKFYKNNQVVLQALNGLFTYLNYILILDKVLGCARFKIYNEVFSLQQCMILDSQAIYHLEILQTTNSVDKKDYSLFGVLNKTVTPGGHRLLRRWVCAPLYQVDQIRERQAMVCDISNFRKERDLFRQSIKQFPDFERRCSRIYEYSIKSESKAVFYENLSEQRLKEFKSLTSTLKLAQEEITLFGQLQINFKSERLRKMMTFEANGGLLPNVQEQLNEFEQYIIWEKEKDKEIPKPVPGVLDTYDQSIAGVQLVQQKLDNYLQQIKKILFKNNGNIQFVHTKFRYEIEIPDELVEKSKPEDFEFTSSRQGYKRYITKEIKDMVTELEQAEELKKQQLNAFGNFIFKHFQSNQSVWDTLIKILNELDALCSLSVFGDTSEGKMTMPTFNTEKTKLVIKEGKHPCLSNINFVSNSIDMGEKLCKFQLLTGPNMGGKSTTLRMVCVLAILAQLGCSVPCEEMELSPIDRIFTRIGAKDYLMEGKSTFYVELEETLIPLKYGTKNSLFITDELGRGTSTYDGVAIASAVMHYLIKTIQCRVLFATHFRILVEEAKLISEVTNVHMACYIQDGKVIFLYRLKEGACEASFGINVAKVVGIENSIITRAEDMANFFENKVQKNTEQTLQKFNQIMKEYGIV
The following text describes a protein:
Function:
Involved in the binding of tRNA to the ribosomes.
Sequence:
MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
The following text describes a protein:
Function:
May be involved in female gametophyte development.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MAFSSCLKFYPFSISQAVTLTHHSFSLNLTPPSSTISFASPHSAALSSTDVKLLDSLRSQPDDSAALRLFNLASKKPNFSPEPALYEEILLRLGRSGSFDDMKKILEDMKSSRCEMGTSTFLILIESYAQFELQDEILSVVDWMIDEFGLKPDTHFYNRMLNLLVDGNSLKLVEISHAKMSVWGIKPDVSTFNVLIKALCRAHQLRPAILMLEDMPSYGLVPDEKTFTTVMQGYIEEGDLDGALRIREQMVEFGCSWSNVSVNVIVHGFCKEGRVEDALNFIQEMSNQDGFFPDQYTFNTLVNGLCKAGHVKHAIEIMDVMLQEGYDPDVYTYNSVISGLCKLGEVKEAVEVLDQMITRDCSPNTVTYNTLISTLCKENQVEEATELARVLTSKGILPDVCTFNSLIQGLCLTRNHRVAMELFEEMRSKGCEPDEFTYNMLIDSLCSKGKLDEALNMLKQMELSGCARSVITYNTLIDGFCKANKTREAEEIFDEMEVHGVSRNSVTYNTLIDGLCKSRRVEDAAQLMDQMIMEGQKPDKYTYNSLLTHFCRGGDIKKAADIVQAMTSNGCEPDIVTYGTLISGLCKAGRVEVASKLLRSIQMKGINLTPHAYNPVIQGLFRKRKTTEAINLFREMLEQNEAPPDAVSYRIVFRGLCNGGGPIREAVDFLVELLEKGFVPEFSSLYMLAEGLLTLSMEETLVKLVNMVMQKARFSEEEVSMVKGLLKIRKFQDALATLGGVLDSRQPRRTYRSR
The following text describes a protein:
Function:
Peptidoglycan polymerase that is essential for cell division.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MKNFRSILRYIGKTSKFIDYPLLVTYIVLSLIGLVMVYSASMVPATKGTLTGGIDVPGTYFYNRQLAYVIMSFIIVFFIAFLMNVKLLSNIKVQKGMIITIVSLLLLTLVIGKDINGSKSWINLGFMNLQASELLKIAIILYIPFMISKKMPRVLSKPKLILSPIVLALGCTFLVFLQKDVGQTLLILIILVAIIFYSGIGVNKVLRFGIPAVLGFLVVFVIALMAGWLPSYLTARFSTLTDPFQFESGTGYHISNSLLAIGNGGVFGKGLGNSAMKLGYLPEPHTDFIFAIICEELGLIGGLLVITLEFFIVYRAFQFANKTSSYFYKLVCVGIATYFGSQTFVNIGGISATIPLTGVPLPFISFGGSSMISLSIAMGLLLIVGKQIKVDQQRKKQQQKVDIRRQFN
The following text describes a protein:
Function:
Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEPRQKKARFFDSEEDFGPDTKSLIRPGSSHKPGKPASNSLARPTPAPSTFRSDLEAFLGPLSDQRFGLLLAKSKGNVEQAVNIHFDLPEEVQQATSEETAEEAEVSQTTTSGFETTQKPSQNTQVPSRVHTRGGCSTSRFIGSLVVTAWASKSSKGKVKYQDRLVVERQSHDHSKSIRKNPTDNSHVHIRTVSGELLGRISGEHDYSIASLIDSRVCDFEASCVYADHNLSLGSNFVVELKCYLTEEAFQDVAMPLLDSKTAKKREYVFDNSRESHVEKMLRNRQIAIVDLFGKLNLIKENEANADMVKDMLRAKSQPPSSQPPSQNSEDESEPIPTDELDALYKRIEKEDVEQPETEVEGFPLELRRYQKQGLTWMISRETEVSEYFDNDDSGPINPLWTKVDFPGSDEKFYVNFSSGALTLKFPKQERSFSGGILADEMGLGKTISTLAMVYRDRHVGCTLVVAPMSLLWQWEQECERVGLSTYVYHEKGADIDLDELFKTYSPNILITSYHTLVSHYGQIKALGGGLDRNVISETSSHERPKIFTKHFHRIVLDEAHVIKNRNTVSAKACCLLRATNKWALTGTPIHNRLEDLFSILKFLGAAPWNDFIYWRNFITLPFQEGKIVSALMTVQCILEPIVLRRTKNMKQADGSPLVVLPKKTINIEKVALTDQERVIYSYVLARAQTSLQKSEASEAVGRNYLNILTQILRLRQSCCDPALILRPEAEVPTDEQLQIEENESQLKSMIQQYNDDTQTSACEYSSEIIAQLQDQSAPPECPICAEDVTKLAISKCLHMGCVDCLADNVRFQESKKQTPVCCICRQPAALKDIFEVERTGEDCKDIRLKKLSDRPRSSKLVALVSKLKQLPKDAKSVVFSQFTSYLDIIQTELRREKIQAFRFDGTLSRQQRTDVLKAFGLSKGSVLLISLKTGGVGLNLVTANHAFIMDPWWTFAQEAQAIDRIHRMGQTKDVHVTRFIVENSVEEKMLKIQQQKMVLAGTLGMSEQEQKAQRIENIKTLLGE
The following text describes a protein:
Function:
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Sequence:
MNEQNENKSTWENLIENKIIKNGFLGCQILNLQGKNLYYYGSYYIDVIEESEIVNYFKESEKDLVNYISIKDLKFLITKDDENKLFGECLNKRIIILKTNNLFLVFWFDINTLSKENANLIVDNFSRTLSNAGYY
The following text describes a protein:
Function:
Involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (MAP), one of the terminal products involved in the biosynthesis of the red antibiotic prodigiosin (Pig). Catalyzes the decarboxylation of pyruvate, followed by the modification of the resulting two-carbon fragment acetaldehyde at the C3 position of the 2-octenal (1,2-addition of acetaldehyde) giving 3-acetyloctanal. In vitro, it can act on a number of alpha,beta-unsaturated carbonyl compounds, including aldehydes and ketones, and can catalyze both 1,2-addition and Stetter-type 1,4-addition depending on the substrate.
Sequence:
MRAATAACRDRRGLCRAEFARLAEAVTPFWLHKELIMTTLTGQARLTNSAAYEQVWQAERQACRTDADPDTLTVGVVVVTRNPAFFQTGLSVLNDIRDYVFNRVHIQSEMPLKLLDLAADSLYLAAREKALHFLKGQNKAINVRIIQCASLAEATGKIIYTHALEQRPEFHLGMLFYDQTTPAGVDDSIEQIDRDLDAFYSALQRSGIPAFYTTFSTVAFIRQLRSPFRYLPQQYREIVRSEDPAIFQTELLCLWMDFFEMNYTNRRVKPIGALALHNTLGEQLIQFFERTAAERWLVSYYTGSIISNLIGYLDRHAEARGALILRGPNEHAIACGAMANWQLYRMPFLGVVTSGMMDEFKGTLANLKETAAQGIIVAAENRGNQWYSFQGTLTPTEDMREVLIARRIPFVYIDDVEMIGAGLTEAFRLYHQGQGPVVILATQNVLESTLSLEGAVCDPSPIPVLSADDPLPMSESLAQAIALINRGPERLVWQLGPVSDDEYALIHDIADAAGIALVDSLAHPGSAPKYYQGRRNPHYLGTLAIYGYSPRVYNFLHTNDKLNAMSEQSLFMIKSRVAQITTPFSDGRLERKVHLVQLTHDDRHLSAYADLHLHMNCLAFLRTVKAHLDVDPALRERRRALIAAYLDSPSDVVSQLPSLPMSANYFFCQLNRVIEELIETEGFDFTGVYDVGRCGISAARNVAKTRRGFSGWYGRALMGDALLATGYLAYTSPSHVMAFIGDGAKGIVPDILPAFIDNILTHPQLLNKSITVFYLCNGGLSVINTYQERILFNRTSRQMRLVNVEQPDVEQTVNNFHIQSKTLTHFDEDVIRQALTTSHRLNLFSVVLGHNNEGDGISPGHRQRLAALIRADHDALQERKAWAAQQPESTSTAFDQDPTQEATS
The following text describes a protein:
Function:
Required for DNA replication initiation. Increases binding of DnaA to oriC region.
Miscellaneous:
MISCELLANEOUS: Estimated to be present at about 3000 molecules per cell A structural homolog of E.coli DiaA.
Sequence:
MKNFYDWIKEFVRDQGEFIAQQSGWLELERSSYAKLIAQTISHVLNGGSLLVSADSSRHWFLNYILSNLNPKDLKERPLLSVIDFNASSFYPKNDANLSLATIEMTYQNPMFWHVGKIENEGLKTILLSKIPSFLWLFEELKEDCLLLKEHDSLLDYKLLQLFKLFENALFSVLYNKVTL
The following text describes a protein:
Function:
Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
Subcellular Localization:
Nucleus.
Sequence:
MSSPPTVILDSSSSSSSDSSEHSDHPSPAKSSKKLSKRKKNQKNNNKPKDKFLITADQWTPIAGPSVPKPNKHQNNHPQETLSLIEPTTNTKLVSLFEPSTSSSSARTATEDLLLAQSNDQEAQQPILVTVEQRVSLYVNCFEEMLNIVLRHEDFLFLPSELRILNSWQALPRSSKYLFVRLFMRKHENWFRLDKLSSYEADVGDLGQTCGSLCKPVDELLAELKRMDPLITLLNNNHCRGGMENIQYPGDQSASHLGGPLNMSTQLEEFNHQYATGGGLNDIHYAGHQLDNYSPCQGTNDPQYPAHQLNPYSPSQASNNLPYAGYQINTYNSPGLGINDVQYTGHQLNLFNPSEGISNAHYTGQQHGIPVTGLFRHSPPAKLDQLNPYNNPYEAINNVQFTSQAHGTHLDGFLKSSPPAKFDPLNLPQHSPNGGMDDAQYSGEQPGISFSDLIRSSPAVEPDHLTTFNHYEGMNDIQWATQQPVSLDELLQCNTHDLAMLEGPYSGALQDTELAYQDQLKSFNQLSPTIPSRIQLGDPSTCPDSPADSLKTDEGIIAQLNVFLDQTSRTKNWTQPPANTLSSHLDQAPNSCRVDESPGPEWIPFDVNDSQTLPDIPPIPPPVDIHPTSITKPPDLVSTTPSVSPSRSQPVESGKDPELSSFATMTSSVDYGLLNTDDLFACMNLDELKSFAKKLNANPHTTRDMIILSIKAVTCKQSTLFGAPSTNKGKQRKQLSLKFTKKGLKESQILSLNSRRPSIKLRPKVCSLFKRLHLIFYRSTTITEKTMTASMLAQMRIRNYPTYTVIRTNSIFESREQLMKYEEALELEKQFDDLMVNERRPWNEDDQGKARRQEAKTVRLKKALDVFESAWLLWQAVILEENDRLDNRLNQGLIYPEYDRSNYYKRRFQPGWPLTRILQKGLAILARFKEYEREVKVLEALIQQPHFRRGKRGQWYDRLALVLMTHLARDESLTVEQRQIHMNSALYTCEHGLKDPDTHQLYRFSLGRRLARLQAIGGALQHPWMDSLETPQVEDWKAARRTTILRTMDNDDRESGVKSRWMSILDNTLLSVEEIALEHYLSDHSHWRGFHSETGILKMIFSLVFWDVIFAPVPGAFETAFQTAPLDIATDAFAIVRRPLIDERMGKIERGGSEEIVNRMRETYVRESGRKTWSIGISQGYWERYRLEDLEQIVRCFSAQAFILISNALFEDYSVWSAGAPDLCLWDPSQMRCKFVEVKGPGDKLSEQQKNWLSLLLKAEGIEVEICSVKED
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase involved in the formation of the rare amino acid 3-methylarginine (MeArg), which is used as a potent antibiotic against the closely related soybean pathogen P.syringae pv. glycinea. Transfers the methyl group from S-adenosyl-L-methionine into 5-guanidino-2-oxopentanoate acid to yield 5-guanidino-3-methyl-2-oxopentanoate, a precursor of MeArg.
Sequence:
MNLLDSIKSENTGFETTLIKGIEPIRQFVLAISIYHLFDTKLFSLLIKHEVASPEVACNELGMEKEKLLGLFRYLKNEGILLETIDGFSLSKEGHALAPFEGWYVMLVGGYATTFLQMGERLQEGAGWATRDATKVGVGSCGISHFDAIPLTRSLMAQAPGTCTKLLDLGCGNGRYLAEFCKALPQIQAWGAEPDRGGFEEAVDLIEKEGLSHRVHISHSGAVEFLDSDFDFEPDFIVLGFVLHEILGQAGRPAVVNFLKKIVHRFPAINLIIIEVDNQFDNAGAMRHGLALAYYNPYYLLHCFTNQLLVQDADWLDIFAEAGLSLVTRETTSDQVDSTGLEIGYLLRRA
The following text describes a protein:
Function:
NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.
Sequence:
MPQQTNLKFPDIASLSISSFSDYHSVSFSGKDVQKEEVIDILDQQGFMPETLMEQEVDWFYESLGIDDLFFSKESPNSIANIIHTLYAAKIESFARTRIGEGDETMAPGVFSIRKKVVTDNHAVFIETGHDLDNQIDAKYMDGTKAYRLVSYYGENNLKLVFLYETKYPSDARTVDAEALVRGEIDLISDVIMSEVTSTENKKLYGQLMHLVAEREGPVIKTFNSVANRDEVRLIVAFRKNTTKRYYSALTSLLHYYHLKPSKIFAETFANDVVIYSIYLNHSEQQEEIVQNLSLSILQVEREASLLYAIPNNFFDLYRLRQFSPQEAIYAHSGSIFVNHFINRLGQDYHTLVKQLNVRPSDTTMLEVLNNLKKKLRNETFTQQMIIDVLHKYKEIVSKLYKNFAQVHYTSAKTSRFEKTLSYQRMSKLEPFKDDTEFELYLTKVIANDSPDLLILRTLKLFNEAVLKTNFFITRKVAISFRLDPTLIMPVAEYPDTPFGVFFVVGSTFKGFHIRFRDISRGGIRIVCSRSQDQYDMNSKMVIDENYGLASTQQRKNKDIPEGGSKGVVLMNPGLTTPTDTFVAFSQYVDAIIDILIQDPKKEKYVDLLDREEILFFGPDEGTAGFVNWATNHARKRGCPWWKSFLTGKTADLGGIPHDEYGMTSLSVRSYVNKLYETLDLKNTKMNKFQTGGPDGDLGSNEILLSTANEQYIAIVDGSGVICDSSGLDKDELRKLARERKMVSNFDKSKFSNCGFFVSVDDVDIMLPNGTIVSNGTTFRNRFHFDIFKFVDRVDLFVPCGGRPSSIDINNLNYYIDPKTSKCRIPYIVEGANLFISQPAKVALEQHGCILFKDASTNKGGVTSSSMEVLASLVLSDDDFLGKFVEVDGKRTPLYEEYVREIQEKIQRNAIAEFDSLWVLNKATGEPISELSNVLSQTINKLNDDLINSNELWLNDLKLRNYLLLNKIIPKLLIDVAGPTNVLNNVPVPYLKALLSSYLSSSYVYLHGLDVNMGKFLEFIGELKRDAENVQLV
The following text describes a protein:
Function:
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.
Sequence:
MKLSVCVILNLDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIKMQEKSVPKAAQDLMTNGYVSLREKDIFVSGVKIFYDSQTGTAKGFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVVTYTDGLPTESAEWFCKWLEEASIDFRFGKTYLKGMRDAVFGLGNSAYASHFHKVGKNVDKWLWMLGAHRVMSRGEGDCDVVKSKHGSIEANFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDRQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQGYQLIGSHSGVKLCRFFFFFIQYSMLRGRGACYKHTFYGIESHHCMETTPSLACANKCVFCWRHHNNPVGTEWRWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMMVKHCALSLVGEPIMYPEINRFLKNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLKALAVKQQQTVYRPTLVKAWNMDELQAYVQLVSLGNPDFIGVKGVTYCGESSASSLTMAHVPWHEEVVQFVRELVDLIPDYEIACEHEHSNCLLIAHRKFKIGGEWWTWIDYNCFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRHQRKNKSKAISGC
The following text describes a protein:
Function:
Neurotoxin that produces dose-dependent hypolocomotion and hyperalgesia in mice. May directly act on the central nervous system, as it is 6500-fold more potent when administered intracerebroventricularly than intraperitoneal.
Subcellular Localization:
Cytoplasm.
Sequence:
MAATNYATALQEELFCPICLDYFTDPVILNCEHNFCRACISTYWESLGDSFPCPQCRKRCRNGKVRPNAQLGKVAERAKELAARDTALPRMPPVAGNKPEPVQEMCKQHLETLKLFCKDDKSLICVVCDKSKEHRNHTVIPVQEAAEEYKAQFQHHLATLKSERDSREILAINNGKKLEMLVDIGSHLNRYKSWSFPKWTPVSTTELEERISHFSHKKTVLWEHMTAMREILTLDPDSAHPSLVISANRRTASCRDICPTHGNTSKRFYPSFCVLGSEGFAGGRHHWLVDVKGQCGWALGVAKESVDRKKPVVLQPERGIWAVELGPCQLFPTTPASKEETETSTRRILVSLDYERGRLTFSDSQDTKPLFTFRTSFTEKLYPFFWLWSPRASITLCS
The following text describes a protein:
Function:
GTPase-activating protein for the ADP ribosylation factor family.
Subcellular Localization:
Cytoplasm.
Sequence:
MGNVGSRLDDSGNLFFKDQTRFTISSATISNSRGRVFLHLTPNSFPATRYTAKREVGDDSPIEYIQDPDLSSSASAPTFLLRLTNEDELNFNFTFILRQTQTANSSNSVVNGVATSLPEVTDTVLTGLTFAHATNSKELDNLITREFHANPNLQNNTNVQFVGDYTTGGSPSVQFNWSWKWKPPKPAEDKGGGWRNSCSFLDYDQRANRLNTLAHFSFWVHNCPRSLPSPQTLSPNLEIPHPVRNRMPSSHSILSHSSDADTTSNLHLPPGTPPETIDNALPPPPPQAPPPPPPVKVDLPHSRPGEDMSVVEDGPLFRATMKALEQKTGNMRAKIKKVLKKAEAAQQAQGACNDAVEAFLSALSEASTTNSNAIQPALDHYFEKIARQILNYERLNTIQLQKLVIEPLVKLYNNDIKQAEAKKKEFEEESRDYYAYVSRYLGQRQDSLKEKKRAESDSKYQAKRRNFELKRFDYSSFMQDLHGGRKEQEVLSHLTRYADEQAKSFLAAAKKVDDMIPQLDALIHEVNQADKEFQFQRTEREEKRRALEKSSNLFLEPDSLANPSVPSSLTGNGSSCHMSESDLGRADSTGSQLRSVVSNSSSMASQTNAAMNSTAGIPPISSNANSSGQQRKEGLLWALSRPGSHIDPKGINKQAWHKFWIVLDQGKLSEYSNWKQKLDLHMDPIDLRMASVREARNAERRFCFEVITPQFKRIYQATSEEDMGNWIRAINNALQSAVEGRGMSPPVPSKNDSSSLGRDIGSVLTGKSSSYSGQHSQSASSVSSVSRRTTVGARPSYVRNDSTGYEENPAKFLQTVRDADQGNNWCADCGSTSKVEWVSINLGIVLCIECSGIHRSLGTHISKIRSLTLDVNSFSNDIVEILLQIGNRVSNMVWEATLDQSQKPMATSTREQRLKFITAKYSDRAFVQPLPSPLSRFSTPDETLLAAIKKNDIQGVLYGIALRADVNITDRSRNTHAVFLALAAADPASPGSTPSNLPPRPSTANAAKAIPFPIAELLVQNGAEIPSQPPPIPLSPAAQLYLSQRTTRYVTPMAGSSTADTVGSLPSIRGTAGDQAVPSGSLDSKERDRLHKRGSAGARFAGKVASLGIER
The following text describes a protein:
Function:
Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.
Sequence:
MTVEERSNTAKVDILGVDFDNTTMLQMVENIKTFFANQSTNNLFIVTANPEIVNYATTHQAYLELINQASYIVADGTGVVKASHRLKQPLAHRIPGIELMDECLKIAHVNHQKVFLLGATNEVVEAAQYALQQRYPNISFAHHHGYIDLEDETVVKRIKLFKPDYIFVGMGFPKQEEWIMTHENQFESTVMMGVGGSLEVFAGAKKRAPYIFRKLNIEWIYRALIDWKRIGRLKSIPIFMYKIAKAKRKIKKAK
The following text describes a protein:
Function:
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
Subcellular Localization:
Lysosome.
Sequence:
MAAKNCDLLCILLATAGNTGEKLYFKYPYSPFLHKKKANKQGTSLTDKHIVDRFHIYDFVLCPWSIRLFALKEDQQELRSRSVSFTSNNFTPDSYIECPLWSFSDSLLASILSPKEAMCNKNFELAIDDILFIGYPTIMKDAENPITASSASGSPASSFKGPATTNLLHITFVLQVGAPPGLIDAFHKLSQRIAAAIKHEQLRRGYLSKEVDLLSFIYDKYSDHAEDITFNVSASLRGGNEYLSGIDDPDEICQKIQPYHSLMMLTNPDNLIRQLPGDCSPALVRLIQVISPFRGSSPLMEEFSNQFVGLFMPVFMSEFSAALRPLKEHIEKFNLSKDMQHRYILLICKLEIRELNFELYENKLSEEDAERLSRQLPNLAYLTDSHKATIMKYVGTKQKEEIQFFIRLCKYFDGRHHIEDIMYWENLPRDEIFEILNRFNEITITFWLRDIVTIAT
The following text describes a protein:
Function:
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity). The CSN complex is involved in the regulation of the circadian clock through its control of the stability of the SCF(FWD1) complex.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MVSSEVRDLLAQVPNWSQADRPAAFRTIITTITSSPDPSHFAADLKAVTDAIFLESLGVVATRALVIDLIDALKSLASGGPSADSINSTTSSIWLDVGKAIQQHIQSNPTLATSLVDQTATIYEELLAAAHESQNSFTDAAKTLAAIPLDSSQRRVTDKYKADLWIRIIRNYLEDDDATSAETYLNKLKNIIHNVADDNPVLNLHFKLSAARIQDSNRQFLAASQSYYEISLSPAIAEEERLHTLSMAIKCAVLAPAGPPRSRVLARLYKDERSASLEEFGILEKMFLDRLLARAEVEKFAQGLAPHQLATTSDGSTVLAKAMVEHNLLAVSRLYRNIGFDALGSWLGLDSGNKAEEITARMIEQGRLAGSIDQIDRIIYFESGLEASGEKGSGRAEVPVGKEMRRQDGMVQALAEDLERITDDLLVEFPQLVPAGVPGN
The following text describes a protein:
Function:
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.
Subcellular Localization:
Nucleus.
Sequence:
MDALIASYGDSDSDTESKSPRLSIPLPPPSLSPSPLPPPPISLLTPPNSFFGTLDDLQTVQAPRVRSFPHVDGNYAVHVYIPVFIPQSARKEAAQFLKKVSLNIPGLHVVDADIPLENLLSDDPKLESIALGREFHISLGRTVPIRVHQIDSMVNMLRQKLQIQKRYWIDFNKWEVFVNDDHTRAFLSLEVTTGGLSEITKQIQAVNEAYRLHNLPEFYKDPRPHISLAWALGDSSDLLRRVVEETKKQPDSGGSVQKRVFTVKFTGIECKIGSKTYKLCKLPGE
The following text describes a protein:
Function:
Involved in galactitol and D-altritol catabolism. Catalyzes the phosphorylation of D-tagatose to D-tagatose 6-phosphate.
Sequence:
MRQASVLAPHTNGPTVTAGEILVEIMATTVGDGFLEPQTLIGPFPSGAPAIFIDQVARCGGTAGIIAAVGDDDFGRLNIERLRRDGVDVSAITTIADRPTGSAFVRYRENGARDFVFNIAHSAASETRMTDEAQALIEKAGHVHIMGSAFAIAGIGAIILEAVKSVKARGGSVSFDPNIRKELAQGDEGRRLIDDLLAVTDLLLPSGEELQAASGLDDEEAAIEKLLAAGIGEIVLKRGANGASHFSRAHGRIDAPGLEVEEIDPTGAGDCFGATYLTCRRLGMRPGKALVYANASGAHNVTKRGPMEGAASLAELDAFMAAQLSEEVL
The following text describes a protein:
Function:
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MVGAVAVTSGDIRLEVGIAKSRLAESLSLHSHSSWSLRVGSTKEAKMVPSLVAADAGKKPSGMVAASALPSSQGVAETAALGAPAVSLEKVVADSSELVASDGSGSVLKNGIEGIRDMARRQRTGSSPTTFSAKFVPFSPGQETDEEYSLDEVIYRSKTGMLLDVQHDMEALKRAGDGNYWKNLFDSRVGKTTWPYGSGVWSKKEWVLPEIDDDDIVSLFEGNSNLFWAERFGKEVLDMTDLWVKHCGISHTGSFKDLGMTVLVSQVNRLRRLGKPLLGVGCASTGDTSAALSAYCAATGIPALVFLPANKISIAQLVQPIANGALVLSMDTDFDGCMRLIRQVTSELPIYLANSLNSLRLEGQKTAAIEILQQFDWEVPDWVIVPGGNLGNIYAFYKGFYMCKELGLVDRMPRLVCAQAANANPLYRAFKNGWETFQPIKALPTFASAIQIGDPVSIDRAIYALSQADGIVEEATEQEIMDACAQADKSGMFTCPHTGVALVALQKLRQRGVIGRNDRTVVVSTAHGLKFTQSKVEYHSSGLPAITSQFANPPISVADDLDSIMDVLRQKLSLK
The following text describes a protein:
Function:
NAD-dependent mitochondrial malic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEGRKAKIDSYQEPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITE
The following text describes a protein:
Function:
Necessary for protein translocation in the endoplasmic reticulum.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Sequence:
MAKGGSQSQASSSTSRPAGAAPRGSAAATAGLRRRRVGGGGGGGGGGSSGFGGGSSNVLSFYTDDAPGLKMSPTVVLVMSLCFIGFVTALHVFGKLYRYRSAANGSP
The following text describes a protein:
Function:
Catalyzes the stereospecific condensation of D-arabinose 5-phosphate and phosphoenolpyruvate to form 3-deoxy-D-manno-octulosonate 8-phosphate (KDO-8-phosphate) and inorganic phosphate. Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO) which is an indispensable component of rhamnogalacturonan II (RG-II), a structurally complex pectic polysaccharide of the primary cell wall. RG-II is essential for the cell wall integrity of rapidly growing tissues and pollen tube growth and elongation.
Subcellular Localization:
Cytoplasm.
Sequence:
MAATSPLYNQLKDAQPFFLLAGPNVIESEEHILRMAKHIKHIATKAGLPLVFKSSFDKANRTSSKSFRGPGIAEGLKILEKVKVAYDLPIVTDVHESIQCEEVGKVADIIQIPAFLYSKTTDLLVAAAQTGKIINIKKGQFCAPSVMNNSAEKIRLAGNPNVMVCERGTMFGYNDLIVDPRNFEWMREANCPVVADITHALQQPAGKKLEGGGVASGGLRELIPCIARTAVAVGVDGIFMEVHDDPLSAPVDGPTQWPLRHLEELLEEIIAIARVTKGKQRFQIDLTPFRD
The following text describes a protein:
Function:
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSFLVSKPERIRRWVSEKFIVEGLRDLELFGEQPPGDTRRKTNDASSESIASFSKQEVMSSFLPEGGCYELVTVIGKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQGELHVSKLFNHPNIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQGVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMISHGQRQRVVHDFPKYSVKVLPWLSPEVLQQNLQGYDAKSDIYSVGITACELANGHVPFKDMPATQMLLEKLNGTVPCLLDTSTIPAEELTMSPSRSAANSGLSDSLTTSTPRPSNGDSPSHPYHRTFSPHFHHFVEQCLQRNPDARPSASTLLNHSFFKQIKRRASEALPELLRPVTPITNFEGSQSQDHSGIFGLVTNLEELEVDDWEF
The following text describes a protein:
Function:
Facilitates ubiquitin-independent proteasomal degradation of polycomb protein Pc by interacting directly with the proteasome and recruiting Pc to it.
Miscellaneous:
MISCELLANEOUS: The name 'stuxnet' derives from a computer (PC) virus of the same name, due to the role of the protein in promoting Pc protein degradation in the proteasome.
Subcellular Localization:
Nucleus.
Domain:
The ubiquitin-like domain is required for Pc degradation.
Sequence:
MDKSAATNSATADGQNEAAAAAAAAATAAGCGSNNSSSTSSSNNTANSNNALQRLATTTSAVVASPMTINLNISTTTGGNFGVSVEPHISVESLKKIIAKKLKVAKDRICLLHREKELQDGTLRDHNLMDGSKIILIPNVETGLLAQRPENTVMQALESLNDAQVNDFLSGKTPLNLSMRLGDHMMLIQLQLSTVNPAGGGAATVAPVAGGASGSSINAAASTTSTVPVMPAGTGCSGANSTSLSSSAVLAAAAAGVGGSTGTSGSGTSSSSSSTSSSSSSSSSSSRTRSSGQRSSGRIGHGHVHSHQHPSLHAANWHGFSHGHGHGHSHGNGHGHHHHHHHHHHHHHHHHNASAVAAGSGGGMSSLRKMYGDLPSSSGASGSAPATGTGQSQSSSTLNGPDLTKLLIKGGIQNIVNSFALKDAGANARPVANGGSGSSPGKPVLEQSPIKSLSNLVSSPIKMTTIKNIPLPTTAATSSSSSCNCSSAAPSSSSSTSSGACATGGCQQDPIAAKLTSCLCTRLPTPSVAPPVATLVAPAPVARSGSTSSPSKCPESSCSGANAGFAARSTLAGTRVTFSGNSMLHKTGNNRITRTKHRHYHGQGHGHGHGNGHSSSSSSSSSSSSSHFFNHACAGNQPSVNAAAFATSSSSSSSSPSSSSSSPSKRRKLEQGMGAGAVGATAATATAAATVALPASTSATTAEPDDSLLGVSDTRTLAEASRNLTQTLRKLSKEVFTNKIDLSGAGVVSSGRSSSSGATSSGAASGEEAPRKSGSGAVIESMKNHGKGIYSGTFSGTLNPALQDRFGRPKRDISTVIHILNDLLSATPQYGRGARISFEAPTTGSVSGSGSGSGSSGSSSTTSSGSGLHHGSRSKMYSSKHHNCAKCNSRAQQQQQQSATLASGSGGSCSFRDCPSYHSSSAATKASTSSKSSSHSCCQTAEAPSSMTSQSNGCTCRYRRDDGQGEREREHTCQKCTVELANMKTRSKMDQLRLVMQQHKQKREARKLKSGPYATAASASAADSLSSIAAGGTAAVPMGAAAQYSAVSALVATPLQPAAVPVQTGKAAPANSITGNSSNANVNGNTSTAPATAATSAAAAPTAAPPSEVSPNHIVEEVDTAA
The following text describes a protein:
Function:
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MSGLLNFGVPKGSLENATVELFRKAGWQISISSRSYFPGVDDDEMNCKLIRPQEMGKYVERGTIDAGIAGRDWVRENESDVVEVCEMVYSKVSRRPARWVLVVTRDSAVQKPEDLHGATISTELVGFTKRYFAERNIPVTVEFSWGATEAKVVDGLCDAIVEVTETGSTIKANGLRIVCDLMESVPVLIANKAAWADPWKREKIETIATLLKSALAAEGMVGLKMNAPNDQLEAITRVLPSLKNPTVSHLFNSDWVSIESILPEKEVRRIVPELIKLGAEGIVEYPLNKII
The following text describes a protein:
Function:
Catalyzes the condensation of pantoate with beta-alanine to form pantothenate. Essential for panthotenate biosynthesis.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MEPEVIRDKDSMRKWSRAMRSQGKTIGLVPTMGYLHEGHLSLVRQSLALTDVTVVSIYVNPGQFSPTEDLSTYPSDFSGDLTKLAALSGGKVVVFNPKNLYDYGGETKKINDGGGNGGRVVSCVEEGGLGHETWIRVERLEKGFCGKSRPVFFRGVATIVTKLFNIVEPDVALFGKKDYQQWRIIQRMVRDLNFGIEIVGSDIAREKDGLAMSSRNVRLSDEERQRALSISRSLAMAKASVAEGKTNCAELKDMIIQQVVGSAGRVDYVEIVDQETLEGVEEIKSGVVICVAAWFGTVRLIDNIEINVSL