lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Plays a role in lysosomes movement and localization at the cell periphery acting as an effector of ARL8B. Required for ARL8B to exert its effects on lysosome location, recruits kinesin-1 to lysosomes and hence direct their movement toward microtubule plus ends. Binding to ARL8B provides a link from lysosomal membranes to plus-end-directed motility. Critical factor involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation.
Subcellular Localization:
Cytoplasm. Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein.
Sequence:
MTSQRVKLKDQILDGIARSVKEVQAYSFSSDGEVVKVNNEARPLQRLVEHLDHAFLHGLKHITPGYWVFVRRFTHKLVISDIIGLDRLATDLGRSRAWLYQSLNEGALESYFRCFQGSEEVLKKFYIEHALMRDSERLTLLMTLVSGLDFVTFDLELNVAYFDLVSHIPRSASNPRDLDDTVSIHSNASLESASSSLVNDLDTHSLLGGIEGGFFPEGSPRDVLQSSLSVDESSVKVCFDDVRAEDTQEASPRDEVEEKEANRSLGNPTEDSSSTCNPSGTESHETDDTNEITRPLTLDLDTQSNNNSSNELKHVTRNYSTPDFDINMDKVAEQDQNLEVIRIRKKAKKKKKRKSSKNDVKPVVKLQEPRRGKRRDRSSSPSTVSIASSCIEEEEEEVEDKESCLGMEGSVEGGEGSLSSAANLSECSAVEEDLDCERVPTSSAPESENTTQECSSGTRLIDLAQHREGRPRRVDGESKETEKRQNVLEHCSEIVTEIVDSMYEDTKKPVSTVDFVVCKEDNVDINREHIRDVVPVRVDTAQLRLPSFADPMTQDGFNSSMDGADQSMIYWQADITDNSFDAEVVSSTPAKSACRVSIQHDHDDVVEDDDVFLRESIAFQSGKDTAEESGDSGIRKHRKANKSDKQKPPQRTLSGTLEYNDTISVELTTQRTDVSAASQDAHLRGQSLISDVPISPDSGINQSFVESSLSKDIITCSSDSLSSGIGSNPDTSNTTTDTNNTTTSSCAPSTPAADSDYGTLDASPHGLSIVQSAEEDVDGFVLVDKNDFLGERSQGDGKDASMDPLCAVDVNAYDSGNPPDAVAVETYDFYCDEDGEKMTTHEAEMKVDNNLKLYLMLEIFKIEDEKYHKLIRLSTGHMEGNLLPAFILLTDLAIYILRRGERNGRFSTESRTLYQELDYVLIGLNYQSVQLVCKNRRKHFWLTTGSQSLTRFFVHSLRAVMKMGNQIDSLCVLTDATAQAIGLKKYVAGEEKVEMSEVEVHLYNLVHWEDLLDSTTAADLQLYLPATKRKGMLHYKTKESFFVGSYWKVAYFKLKQNVLKRYPRKEAEEPDLIIDLGSQRFGGCRRVHNTDRRFSFELVLTDGSQPLRLSCENELELSHWLQSICEVASHQHSMSQMKGPKPNPCQPSCAVITSRSVLLCLEDYQTHFFRTLARTDLGTISRVERSKSNLSYLVMSFRNTDCDNPWLLYFNCSRELDKFVNHLSQAFHQRTQKDLKISTIQDEKLARRCSNCQDLILSAWQRSDSLGRGRVRGDSW
The following text describes a protein:
Function:
Protein kinase involved in signal transduction pathways that regulate various cellular processes. Likely senses intracellular peptidoglycan subunits present in the cell division septa of actively growing cells; thus, intracellular unlinked peptidoglycan may serve as the signal molecules that trigger StkP phosphorylation activity on a set of substrates. Plays a crucial role in the regulation of cell shape and cell division of S.pneumoniae through control of at least DivIVA activity. Identified target substrates that are specifically phosphorylated by StkP in vivo, mainly on threonine residues, are DivIVA, KhpB (also called EloR/Jag) and StkP itself. Autophosphorylated StkP is a substrate for the cotranscribed protein phosphatase PhpP (shown in the avirulent strain Rx / Cp1015); PhpP and StkP appear to constitute a functional signaling couple in vivo.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Note=The kinase domain is located intracellularly, while the C-terminal PASTA domain is exposed extracellularly. Localizes to the midcell division sites. Time-lapse microscopy shows that StkP displays an intermediate timing of recruitment to midcell: StkP arrives shortly after FtsA but before DivIVA. Furthermore, StkP remains at midcell longer than FtsA, until division is complete. Delocalizes from the septum in the presence of antibiotics that target the latest stages of cell-wall biosynthesis and in cells that have stopped dividing.
Domain:
Consists of an N-terminal kinase domain, a transmembrane domain, and a C-terminal domain containing four repeats of the PASTA signature sequence (Penicillin-binding protein and Ser/Thr protein kinase associated domain). The PASTA domain binds to peptidoglycan (PGN) subunits (shown in strain Rx / Cp1015), is essential for StkP activation and substrate phosphorylation, and is required for cellular targeting to midcell.
Sequence:
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQNPLPSVIAENSSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQAPKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVSKPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVEGMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP
The following text describes a protein:
Function:
Plant-specific factor involved in mitochondria fission. Is required for the correct localization of DRP3A from the cytosol to mitochondrial fission sites. Does not seem to be required for peroxisomal division.
Subcellular Localization:
Mitochondrion outer membrane; Peripheral membrane protein.
Sequence:
MRPILLPDPPSLSTGVPDIFEQGGSHNVVRRAVVIGNGFPGSENQCIGLVRALGLSDNHLLYRVTRPKGGLNEWLHWLPVGFHKKLDFILRHIYLYSRLMLGSKQSKYISSVPSENGGNVGLASILEADVKGIVNLARQTYEKDGPLIVIACGRDTISIASSIRRLASENVFVVQIQHPRSHLNRFDMVITPRHDYYPLTLEAQEQVPRFMRSWITPREPPQDHVVLTTGALHQIDYASLRKAASAWHDEFAALPKPLVVVNIGWPRSNCRYGADLAKQLTDSLLNVLATCGSVRITLSYKTPAKVSRVIFKELGDNPKVYIWNGQEPNPYMGHLAWGDAFVVTADSVSLISEACSTGKPVYVVGADHCKWKIAEFQKSLRERGVVRSFTGFEDMSESWSYPPLNDTAEAATRIRRELAARGWSLRS
The following text describes a protein:
Function:
Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the endoplasmic reticulum membrane. Plays important roles in controlling the metabolism of fatty acids at different levels. Also acts as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
Subcellular Localization:
Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum membrane. Note=Translocates from cytosol to endoplasmic reticulum membrane with increasing levels of oleate.
Domain:
Contains 1 Asp-Xaa-Asp-Xaa-Thr (DXDXT) motif, a catalytic motif known to be essential for phosphatidate phosphatase activity; Contains one Leu-Xaa-Xaa-Ile-Leu (LXXIL) motif, a motif known to be a transcriptional binding motif.
Sequence:
MNYVGQLAGQVLVTVKELYKGINQATLSGCIDVVVVRQQDGSYQCSPFHVRFGKLGVLRSKEKVIDIEINGSAVDLHMKLGDNGEAFFVEETEEEYEKLPAYLATSPIPTEDQFFKHIETPLVKSSGNERPAQSSDVSHTLESEAVFTQSSVKKKKRRRKKCKQDNRKEEQAASPVAEDVGDVGVSSDDEKRAQAARGSSNASLKEEDYKEPSLFHSGDNYPLSDGDWSPLETTYPQAVCPKSDSELEVKPSESLLRSEPHMEWTWGGFPESTKVTKRERYDYHPRTATITPSENTHFRVIPSEDSLIREVEKDATVEDTTCTIVKPKPRALCKQLSDAASTELPESPLEAPQISSLLDADPVPSPSAEAPSEPKPAAKDSPTKKKGVHKRSQHQGPDDIYLDDLKALEPEVAALYFPKSDTDPGSRQWPESDTFSGSQSPQSVGSAAADSGTECLSDSAMDLPDVTLSLCGGLSENGEISKEKFMEHIITYHEFAENPGLIDNPNLVIRIYNRYYNWALAAPMILSLQVFQKSLPKATVESWVKDKMPKKSGRWWFWRKKESMIKQLPETKEGKSEVPPANDLPSNAEEPTSARPAENDTSSDEGSQELEESIKVDPITVETLSHCGTASYKKSLRLSSDQIAKLKLHDGPNDVVFSITTQYQGTCRCAGTIYLWNWNDKVIISDIDGTITKSDALGQILPQLGKDWTHQGIARLYHSINENGYKFLYCSARAIGMADMTRGYLHWVNDKGTILPRGPLMLSPSSLFSAFHREVIEKKPEKFKIECLNDIKNLFAPSRQPFYAAFGNRPNDVYAYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFPLLSKEQNSAFPCPEFSSFCYWRDPIPDLDLDDLA
The following text describes a protein:
Function:
The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment.
Sequence:
MERLYKAFGDDFLELYKREIGISQPRNFARRISASEVTVKRLDLYGKLNGHEGCVNTIDFNATGDVLASGSDDRRVILWDWATRKSKLSYQSGHMDNIFQAKFMPFTDDRRIVTAAADGQVRLGLLLENGQVETKRLGRHQGRVHKLAVEPGSPYIFYSCGEDGFVQHYDLRSNSSTKIFRCSSLAENNKQSSSSISLNAIVIDPRNPNYFAVGGSDEYARVYDIRMYEMDALHNSDRPVNTFCPPHLIKAHDVHITALAYSSSSELLVSYNDELIYLFQKNMGLGLSPLSSRGEDAKKLEEPQVYSGHRNSRTIKGVSFFGPYDEYVLSGSDCGHIFIWKKKGANLVRLMAGDKHIVNQLEPHPCIPVLATCGLEKTIKLWTPSSNNVSALPRDVLKIMEANRRGREDHSRVTLTPDVIMHVLRLQRRQGVAYVERRHSRDDVESDEDDGEEAYILGFPDSDTEEGVTGNSECSIS
The following text describes a protein:
Function:
Snaclec that induces platelet aggregation without any cofactor in a dose-dependent manner. Its platelet aggregation effect is blocked by echicetin, suggesting it is a GPIb-binding protein which binds to the same or a closely related GPIb site on platelets as echicetin.
Subcellular Localization:
Secreted.
Sequence:
DCPSDWSSFKQYCYQIIKQLKTWEDAERFCLDQMKGAHLVSIESYREAVFVAELLSENVKTTKYHVWIGLSVQNKGQQCSSEWSDGSTVSYENLVKPNPKKCFVLKKESEFRTWSNVYCEQKHIFMCKFLGSR
The following text describes a protein:
Function:
Glucose-regulated GTPase-accelerating protein (GAP) for the GTP-bound self-activating heterotrimeric G alpha protein GPA1. Cooperates with G beta-gamma dimers to maintain an unactivated but fully functional pool of GPA1. Phosphorylation-dependent endocytosis of RGS1 physically uncouples the two proteins, resulting in signal activation. Free AGB1 is essential, but not sufficient, for RGS1 endocytosis. Modulates cell proliferation, abscisic acid (ABA) and drought stress signal transduction by acting in a hexokinase-independent glucose-signaling pathway. Involved in the shapes of leaves, the development of floral buds, the elongation of stems, siliques, and hypocotyls, the time of flowering and the regulation of guard-cell K(+) and anion channels. Important for the kinetics of voltage activation of inward K(+) current but not for the current amplitude.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=accumulates at the nascent cell plate during cytokinesis.
Domain:
The C-terminal domain (249-459) is able to bind to and to accelerate the GTPase activity of GPA1.
Sequence:
MASGCALHGGCPSDYVAVAISVICFFVLLSRSVLPCLIHKAPRTNSSSFWIPVIQVISSFNLLFSIMMSVNLLRFRTKHWWRYCYLWAVWIEGPLGFGLLMSCRITQAFQLYFIFVKKRLPPVKSYIFLPLVLLPWIFGAAIIHATKPLNDKCHMGLQWTFPVAGLHALYVLALIAFTRAVRHVEFRFDELRDLWKGILVSATSIVIWVTAFVLNEIHEEISWLQVASRFVLLVTGGILVVVFFSISSNQPLLSQISLKKRQNFEFQRMGQALGIPDSGLLFRKEEFRPVDPNEPLDKLLLNKRFRHSFMEFADSCYAGETLHFFEEVYEHGKIPEDDSIRRIYMARHIMEKFIVAGAEMELNLSHKTRQEILTTQDLTHTDLFKNALNEVMQLIKMNLVRDYWSSIYFIKFKEEESCHEAMHKEGYSFSSPRLSSVQGSDDPFYQEHMSKSSRCSSPG
The following text describes a protein:
Function:
Part of the energy-coupling factor (ECF) transporter complex NikMNQO involved in nickel import. The complex confers nickel uptake upon expression in E.coli; can also transport cobalt with a very low affinity.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MHIPDGYLSPVTCAVTFAATVPFWYVSMRKLDRDLNGQHLPLVALVAAFSFVIMMFNLPIPGGTTAHAAGIGIAAVLLGPWAAVPAISVALLIQAIFFGDGGITAFGANCLNMAVVGPMVAAAVYALGTRGAAIGSRRRVIMAGLASYAGLNAAALLAAVEFGVQPLFFHDAAGAPLYAPYPLSVAVPAMALTHLTIAGAAEFIVTAGLVAWLQRSNPELLAPRRAPAAPERHLRLWAGIGALVVLCPLGLIAAGTAWGEWGAEDFTSEAGRAAMAGASGGVAPPAGLPGGFARLAELWSAPLPDYAPAFVQNAPLGYVLSALLGVALIVAGIGLSAGLRALTRRAG
The following text describes a protein:
Function:
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Subcellular Localization:
Nucleus.
Sequence:
MLSPDPFADCQDHDDSFENFLPTPSTSRRRSEAIVLSEEDSLDGLIGSEQVTVIENVPNDTILKEQEDDDSGDEQVNLDDTITRMLESSDEEEADIEVEPQNDALANLLRSFTEGTTKRGHAEQEEEREDDPNMSIDVFGDLMQNKPEEEKEEEEETQVLPNSRMIPVHLPNQKEAITRKRRCEPSEPSTSTAPLGTDGPVGVVSSDTGEYWNQPKTITVHGQNFEINSFNDYMRMKITKLNHQVNSEKSKPYEKVSETLKGYSVFVNGYTEPPALVIRDLMMAHGGEYHCYYQHGITTYTIASSIATAKVNRIREKEIFIRADWITESIAAGKPLDYRDFLIYEKGAQEKGQMQQFLRSSNDKPIETSSTSSSSGFLDARNPNFIRDYYARSRLHLISTLAQDMKDFVANLKLEGKLTAKCFLENELAEMGRKLGTGTGIQTNTVFHVDLDCFFVSVAVRDRVDLRDKEVAITHSKGTISNSMSEVASCSYAARSCGVKNGMLVRDALQKCPQLTLLPYQFDDYIQVSRQIYEILASYTLDLRAVSCDEMYINMSSLCEKYGISDPTAFADHIRKVIREKTRCPASVGIGSTSLLARLATRHAKPDGVFWVTEEKKTEFMLEEKVRDLPGLGYEMMNRLTSFFGEITTCSQLQQRTERELIPVFGPKLATKVFNQCRGTEEDPENFWKTHVRKSVSCDINYGIRFKKKEEVLQLMTAIGAELERKLLDCKMSAGSITLKLMVRSADAPVQTSKFMGHGRCDTFTKTCNISVSTTKGKILTSECMRLYAKVSPNTEDLRGVGVTCGKLKSKFRKDAASVVQEMFGKGKRDPNADDPIQKKPIELEEDDDRHMRNKVVNIPSTSNQNQKTRNIAHPTDVRIANEITLPGLIKLSKCYIKKSVKTYEDVEDEELEEKCLAELGTFLQDAPAKHSVLGVLEILEELLNAGKLSTFQSVFRKFEEMSMNSTTYHVDWFAAFHSLVPHIKETSERLLEFPVDVLQNVIGKLGTTATGTAESHLKPTAP
The following text describes a protein:
Function:
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Subcellular Localization:
Secreted.
Sequence:
MAPLGPTGPLPQSFLLKCLEQMRKVQADGTALQETLCATHQLCHPEELVLLGHALGIPQPPLSSCSSQALQLMGCLRQLHSGLFLYQGLLQALAGISPELAPTLDTLQLDTTDFAINIWQQMEDLGMAPAVPPTQGTMPAFTSAFQRRAGGVLVASNLQSFLELAYRALRHFAKP
The following text describes a protein:
Function:
Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MIDIDHVSYTYPGATEPILRNLSLQIAPGEFLLVCGPGGVGKSTLLRLFNGLVPHFYGGHFRGRVRVWGRDTLQHQPRDLADLVGFVVQDPESQFVVERVEDEIVFAMENLGVPPPMMRRRVEEVLDQLAIAHLRHRHVATLSGGEQQRVAIAAALAAQPRVLVLDEPTSQLDPHGAEEVLTALQKLNSDLGITIVLCEHRLERVVQYADRILYLSPNGESDLGPPREVLSRIDLRPPLQHLGAVLGWQPLPLTIKEGRKFVPSDLPDFTSPASPSPPTTTAPIARLRNVTVRYGQHEALYRVQLDLPRGALIALMGRNGSGKSTLLKTLIGLVRPSEGRVELEGRDIAPLAVEELARHVAYVPQQPRSILFHDTLEEEIAFSLRGRRLSPTQSAIRDILTRFRINHLIARYPRSLSGGEAQRAALAASLAGDPQLILLDEPTRGLDYHAKHALIDTLRSLCRDGRTVIMATHDVELVAACADWVVLLSEGEVVVEGSTADLLGNSLIFSSQIAKLFPGQGWLTVPQALDGLGWRSP
The following text describes a protein:
Function:
Epoxide hydrolase involved in the biosynthesis of cucurbitacin and mogroside tetracyclic triterpene natural products (e.g. siamenoside I and mogrosides IV, V and VI). Cucurbitacins have cytotoxic properties and exhibit deterrent taste as a defense barrier against herbivores. Mogrosides are nonsugar highly oxygenated compounds used as high-intensity zero-calorie sweeteners; they also possess pharmacological properties such as regulating immunity, lowering blood sugar and lipid levels, protecting the liver, and acting as antioxidants and antitumor agents. Catalyzes the hydrolysis of aromatic epoxide-containing substrates, such as the conversion of 24,25-epoxycucurbitadienol to 24,25-dihydroxycucurbitadienol.
Sequence:
MEGIKHQMVKVNGINIHIAEKGEGPVILFLHGFPELWYSWRHQILALSSMGYRAVAPDLRGYGDSDAPDSVESYTCFHIIGDLVELIDVLDPDVGKVFVVGHDWGAYMAWLLCLFRPDKVKALVNLSVPFLRSHREIKPVDFWRSYYGADHYISRFQKPGEIEGEFAEIGVERVEKELLTDFPVILPKGKLFKRPLDEPITLPSWLSEEEANYYVTVFQKTGYTGALNFYRNFNRNWELLKPWVGSKIKTPAKFIVGDKDLVYHMPGMKDYIHNGGFQEDVPSLQQVVVMEGVAHFINMEKPDEINKYISDFFTQFV
The following text describes a protein:
Function:
Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.
Subcellular Localization:
Nucleus.
Sequence:
MPVLQKLYQQVPECEPFLYPVDPIGLGIPVSFSFLRDFHECDYHAIIKHPMDLSTIKDKLDNGIYENPWEFIDDVGLMFDNAWLYNRKTSKVYKYCSKLSEVFDNEIDEAMISLGYCCGRRHVFSPQVLCCFGKQLCSIPRDTVYYNYLDRLVCWAVVDDVVMYIYCEKCFNELQGEEVEMVDDPSQPGLKIKKGQFVREKNDKLDHEQFVNCKECDRKMHKICVLHMENIWPEGFLCDYCLKALQTKRKENKYSAKRLPTTKLGTYLETRVNSLLKKKNSGAGEVTIRVLSSYDKVVEVKSGMKARYVNRSEMPEGYPYRVKAMFAFEEIDGIDVCFFGMHVQEYGSDCPMPNSRRVYIAYLDSVHFFQPRHLRTTVYHEILIGYLEYAKIQGYEWAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQDWYKKMLDKAYQDRVIIDYKDIYKDAIEGNITKVTDMPYFEGDFWPNILEECIKDLEQEEVEKRKRAEEEAAQDTDDFESDINDRAELETFAGKKKGQKSGNQKKKNTKSKKPSNRKNKTGLMHCGNDLSAKLLSTMEKHKEGFFVIRLQPINNCPVEIRDVDPLMNCDLMDGRDAFLTLARDKHYEFSSLRRAKYSSMGLLYELHNQARDGFIYSCNDCKANVETRYHCSVCDDYDLCVSCYKKSDHPHKQQMTRLGLDLDGDSSNDASNNNLASDQQNSKGPNTQEAKNISINSYISSLVHASHCRDANCRLNVCQKMKRFMQHIRTCKRRQDNSCKVCKQLLLLCWTHAKQCKESKCPVPFCINLKQKLEQQKAEAQFKNNQLMRRRMAIMQRQPALDRAEHTPLSNAPPNSDPPTPTAMGPPHGGGGYGGNGGKFLHHLGGSPPPSMPPHQAAMMAAHQAEQMAQTQRQVPPVYGAGSGG
The following text describes a protein:
Function:
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. In the complex, plays a central role in bridging PI4KA to EFR3B and HYCC1, via direct interactions.
Subcellular Localization:
Cell membrane. Cytoplasm.
Sequence:
MAAKGAHGSHLKVESELERCRAEGHWDRMPELVRQLQTLSMPGGGGNRRGSPSAAFTFPDTDDFGKLLLAEALLEQCLKENHAKIKDSMPLLEKNEPKMSEAKNYLSSILNHGRLSPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLHWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALIRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MIHTERIVSLTLEILSLLTGEDYIVVKKQSKEGAATSRLPTPDGDDKSQSHKPDPPGSSLIPKQNPREKGLEPAGPEVVLRWDDAAVYLSVEEWEYLKGHKEQYQQAVMEDCQPVCSVGCDTGNPTPQQSKRDRELKLEPQEERIHPGCDTANPTPRRSKRDTEPKPEPQEERIHPDTPLVSEIQTDGPHINPSHEYLNIVTVMETDQKESLAECPSPDRKKDDAMKDRSLEKETRFRVSPRRHRRGKYRPTGNPGVGRAPETPIYEFKIQSDVNCLPSDGNLNRGSSAPQGNRPKISAVITSQKQTDAKCGKEISKHYSQRLGPDNERQFVCSFCGKCFRSYCYISRHIRSHTGEKPFQCPVCSKCFSDKSVLIRHHKSHTGQRPFTCSYCEKCFSHRAGLLEHLSLHAGDRPYVCPECGKCFKYRASLTSHRRIHRGKSICV
The following text describes a protein:
Function:
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
Sequence:
MFPRPNRKPGVPYSDFPVDEMGNKSEMITHGTPSRYSFVIEGLDGYWAHVERCNSNRDKRKDYLPFIAGQGLHVGFIHPKFAEELKRFPGIFTFSGDKAKGQMVQLNRTLITEKDCTASVEGVMQILANEGKIHSWRNEKYPVVTSFGSPSLFWLERACVPYLGTKAYHTHLNGYTIVDGEMFLWVSIRGDSKMHQDFPGKYDHLVAGGQPVNLTPKENILRYAQARANMPSDMAEKAIPVRTISYEQIDDQKMKRDVIFCYDLEVPYFWQPKNNDGEIDSFKIMRVTEVAKIIRSSTGSYKANSALVVIDFLYRHGFINPNEHGYLELQQSLQQGENE
The following text describes a protein:
Function:
Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
Subcellular Localization:
Cytoplasm. Rough endoplasmic reticulum.
Sequence:
MSQVQVQVQNPSAALSGSQILNKKQSTLSQPLMSIPSTASSLPSENAGRPIQNSALPSASVTSTSAAAVPSNMANPKEKTPMCLVNELARFNKIQPEYKLLSEQGPAHSKVFTVQLTLGDQRWQSEGTSIKKAQHGAATKALQGTRFPKPTARPARHEGRNPDSVTPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRAGAYPPRYFYPFPVPPILYQVELSIGGQQFNGKGRTRQAAKHDAAAKALKILQNEPLPEKPEVNGRVPDDENLNKSEISQVFEIALKRNMPVNFEFFPLKQVTKENGPPHMKSFLTKVSVGEFTGEGEGKSKKISKKNAAIAVLEELKKLPPLPTVEKMKPRIKKKTKSIVKLPTSPEYGQGMNPISRLAQIQQAKKEREPEYLLVTERGLPRRREFVMQVKIGVHTTEGAGTNKKVAKRNAAENMLELLGFKVPQPQPPKPALKTEEKTPVKKPGDGRKVTFFEPGCGDENVTNNKDDEFRMPYLSHQQLPAGILPMVPEVAQAVGASQGHHTKEFSRVAPNPAKATVTAMIARELLYGGTSPTAETILKNNNPSAHAPHGPLTRPSEQLDYLSNVQGIQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQNTEMPRTGNGPMSVCVKQEMEGDPLLKPANSNTLGQALDSSA
The following text describes a protein:
Function:
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes.
Subcellular Localization:
Nucleus.
Sequence:
MEMESFMDDLLNFSVPEEEEDDDEHTQPPRNITRRKTGLRPTDSFGLFNTDDLGVVEEEDLEWISNKNAFPVIETFVGVLPSEHFPITSLLEREATEVKQLSPVSVLETSSHSSTTTTSNSSGGSNGSTAVATTTTTPTIMSCCVGFKAPAKARSKRRRTGRRDLRVLWTGNEQGGIQKKKTMTVAAAALIMGRKCQHCGAEKTPQWRAGPAGPKTLCNACGVRYKSGRLVPEYRPANSPTFTAELHSNSHRKIVEMRKQYQSGDGDGDRKDCG
The following text describes a protein:
Function:
Catalyzes the glycosylation of 4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C1'' position with the carboxyl group of 4,4'-diaponeurosporenic acid, to form glycosyl-4,4'-diaponeurosporenoate. This is a step in the biosynthesis of staphyloxanthin, an orange pigment present in most staphylococci strains (By similarity).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKWLSRILTVIVTMSMACGALIFNRRHQLKAKTLNFNHKALTIIIPARNEEKRIGHLLHSIIQQQVPVDVIVMNDGSTDETARVARSYGATVVDVVDDTDGKWYGKSHACYQGVTHACTNRIAFVDADVTFLRKDAVETLINQYQLQGEKGLLSVQPYHITKRFYEGFSAIFNLMTVVGMNVFSTLDDGRTNQHAFGPVTLTNKEDYYATGGHKSANRHIIEGFALGSAYTSQSLPVTVYEGFPFVAFRMYQEGFQSLQEGWTKHLSTGAGGTKPKIMTAIVLWLFGSIASILGLCLSLKYRQMSVRKMVALYLSYTTQFIYLHRRVGQFSNLLMVCHPLLFMFFTKIFIQSWKQTHRYGVVEWKGRQYSISKEQ
The following text describes a protein:
Function:
May be involved in membrane trafficking.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MGFLFGLFIGIAVSIGLVVSFARYSNVRSIRRAELARTIAAFARMTVQDSRKLLPGEFYPSWVLNWLNLELEKIWPYVNEAASELIRSSVEPVLEQYTPAMIASLKFSKLTLGTVAPQFTGVSILENESGPNGITMELEMQWDGNPKIVLDVKTLLGVALPIEVKNVGFTGVFRLIFKPLVDEFPCFGALSYSLREKKGLDFTLKVVGGELTSIPGISDALEETILDAIEDSITWPVRKIIPILPGDYSDLELKPVGTLDVKLVQAKDLSNKDLIGKSDPYAVVFIRPLPNKTKKTKTISNSLNPIWNEHFEFVVEDVSTQHLTVRVFDDEGVGSSQLIGAAQVPLNELEPGKVKDIWLKLVKDLVVQRDTKNRGQVQLELLYCPLGKESGFKNPFNPNYSLTILEKVLKPESEDSDATDVKSSQSPNKTDVIVRGVLSVTVVAAEDLPAVDFMGKADPFVVITLKKSEAKSKTRVVPDSLNPVWNQTFDFVVEDALHDLLIFEVWDHDKFGKDKIGRVIMTLTRVMLEGEFQEWYALDGAKSGKLCIHLKWTPRLKLRDAS
The following text describes a protein:
Function:
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
Subcellular Localization:
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Sequence:
MRLLILILLSVLVLFQYNFWFGSNGFLDYRQNAEKIKENQAENEKLSQRNQRINAEIQGLTKGFEAIEERARMQHGLVKENEVFYHIVKESK
The following text describes a protein:
Function:
C-methyltransferase that acts together with NovW to catalyze the formation of dTDP-4-keto-6-deoxy-5-C-methyl-L-lyxo-hexose from dTDP-4-keto-6-deoxy-D-glucose in the novobiocin biosynthesis pathway, an aminocoumarin family antibiotic that targets bacterial DNA gyrases.
Miscellaneous:
MISCELLANEOUS: It is unclear whether NovU acts before or after 3-epimerase NovW in the novobiocin biosynthesis pathway.
Sequence:
MQDIVRPIDECRVCGHDDWLDVVSFGSTPLAGNLLGDEDDAGGETLFPLDVVVCRRCWLMTLRHVIEPDVLFGHYRYVASDAGSIIQHMRKLVDLCVERIGLTDGDLVVEFGSNTGAHLELFRQAGPRVVGVDPARNLAGVANDRGVETIPAGFTAEVGEEIATRHGLARLVYGRQCFAHIPDIHEVLNGVSALLAPDGLFFVEVPYLVELLKNNQFDTIFHEHFSYFSLGSLCTLFESHGLRVVDVHTADVHGGSIVVFAAPAAADHEVRPAVAEMLAEERSQGIAEERTYREFADRTERVRAQIRELVRGVVADGKTVAGYGAPTKGSALLAACGLGHQEIRFCSDTTVLKQGKILPGSRIPIWSPEQAAGHVPDYYLLLAWNYAPEIIDNEKEFLENGGRFIVPIPEPRVISAESTL
The following text describes a protein:
Function:
Product of a dosage-sensitive gene that contributes to the maintenance of paternally and maternally imprinted gene expression in the endosperm in order to balance parental contributions. Underlies postzygotic reproductive isolation by promoting triploid seed arrest in a genetic dosage-dependent manner, thus being a component of postzygotic interploidy hybridization barriers.
Miscellaneous:
MISCELLANEOUS: In Greek mythology, 'Admetos' was one of Jason's companions Argonauts in his quest for the Golden Fleece; MISCELLANEOUS: Product of a paternally expressed imprinted gene (PEG).
Sequence:
MFSGEGASQIRIAPEDKPIQWCYQILKSRDFKSARYITQMNLKLSKTRHDEYEKGLAICDILIAAENRLPNGLLDCYGMIRMTRPGLVLYQNIEKELNLLGWGNISNPFPFRQEASEKFFFAWSLLSNPTIKEMYDYATSDEVNLEPQGNVNEYMDVDSSSQSGYGLGSVLCSDLPGSEYLKEFADVYPLPLAEKGQAPHNRFGWYDHNVGPETNNNVVVTYEDAKEEECDMSSSSELRIINGRRVKITIEEAAETSDTPSCSR