lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in monoterpene (C10) biosynthesis. The major product is S-(+)-linalool. Linalool production is induced by jasmonate in response to pathogen attack, it possesses antibacterial activity and is important for resistance to the bacterial blight pathogen Xanthomonas oryzae pv. oryzae (Xoo). Plants over-expressing linalool synthase display enhanced resistance to Xoo.
Subcellular Localization:
Plastid, chloroplast.
Domain:
The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
Sequence:
MVCHVFSSFSSSLIRVLEAPLLLPAASASSSSSSSPASRSGGRRRRAAHVRPSPAIYPGRQELASHSSMLPTDFDIKVLIERHEALTDDVQEMLQHQRRRHQKTASGGRERIATVDHLRRLCMDHYFQDEVDDAMDACLLEELAHGGDLLDATLAFRLMREAGHHVSADEVLGRFTDDNGEFRLDYRKDIRGLLSLQDISHMNIGQEASLCKAKEFSTRNLESAINYLEPNLARYVRQSLDHPYHVSLNQYKARHHLSYLQTLPIRCTAMEELALADFQLNKLLHQMEMQEIKRWWMDLGLAQEIPVARDQVQKWFVWMMTAIQGASLSRCRIELTKIVSFVYIVDDIFDLVGTREELSCFTQAIRMWDLAAADSLPSCMRSCFRALHTVTNDIADMVEREHGVNPINHLKKAWAMLFDGFMTETKWLSAGQVPDSEEYLRNGVVTSGVPLVFVHLLFMLGHDVSQNAAEFVDHIPPVISCPAKILRLWDDLGSAKDEAQEGLDGSYKELYLKENPGLAAGEAEEHVRRLIAGEWEELNRECFSASPSRSSPATTFPAGFTQAALNAARMVGVMYGYDGERRLPVLDDYVRMLLF
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MDDYTVATLAWKAAVPFTPDLPTHLHSSIGFALLASAFGLGFLFTTLPKTGFPTTELIPALMASLLTGFGVVFLFNAAGVYV
The following text describes a protein:
Function:
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
Subcellular Localization:
Chromosome. Nucleus.
Sequence:
MSAPAPVAPKKKVARRPKKPAAHPPVAKMVVAAIAALKDRKGSSLQAIKKYIAANYKFDVTKQGHVIRRVVRNMLAKGLLTQAKGKGAAGSFRLGAAAKKAPKKRKAKKPKKKAKKPKKARKPKAKKAKKPKAKKAKKAKKPAAKKAARKPAKKTKRVAKK
The following text describes a protein:
Function:
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
Sequence:
MSQPIPSASPALAALIERAVARVRHALPADAPWPEGVEHPLARVALASDFVVDTLARQPALLAHLAQPDPPPLPVPRLDPAQPQEWAAQLRRYRAAASARLVWRDVLGLDDVDATLAGATTLAETCLQCALQALEQQFSTRHGQVIAEDGSVQRLVVFGLGKLGGGELNFSSDVDLVYAYPQAGQSDGARPLAAEEYFARLGQQLARLLDETTADGFSHRVDLRLRPFGSAGRVALSFNGMDQYFQREGRDWERYAWLKARAVAGDIAAGEAWLETLRPFVYRRYLDFTALDGLRDMKAAITAEVAHHARLDDIKRGPGGIREIEFLAQSLQLIRGGREASLRERRLLPALQALVDLGQIDPPTGQALADAYRFLRRVENRLQMLRDAQTHALPQGEPERERIALGLGYAHWQALLEALAPHRTRVAAEFAELLAPRVHATAPDTLADYWRALPEGDAAPLLGIGLHDPNNAHHMLADFAQSSGVRALSDGARTRLDRVMPALLHAAIRATQPDAALRRVLGLLQATLRRTSYLALLDEQPSALARLVDVLSRSALLAERLAAYPLLLDELLDTRISGPLPDRAALHTACVDTLQIDDTEAALRELNERRLALSFRIALATLDGRQQPVDSTQQLAWLAEAVVQTVLQLARRELVAAHGQVPGGAFAIIGYGSLGGLELGFGSDLDLVFLYDHPREVEASDGKRPLEAGRWFARLAQKVMTLLGAETGAGRLYDIDVRLRPDGGKGALVSSLASYRDYQRDRAWTWEHQALVRARAVAGDAALCEAFVQVRRETLTRVRDPALLHEDVRKMRARMRSELDRSDAGRLDLKQGAGGLVDLEFLLQAGVLGQAAQHPALLLACATPALIDALVQVQWLPAESAAPLHHAHATLVEAGLSCTLDRRPRLVVSTPPIRDACQIVAAIADAQQLRFQPGKGA
The following text describes a protein:
Function:
Might insert into membranes and form chloride ion channels. Channel activity depends on the pH. May play a role in ethanol sensitivity.
Subcellular Localization:
Mitochondrion. Membrane; Single-pass membrane protein.
Domain:
Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as a chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
Sequence:
MSEVESQQSQETNGSSKFDVPEIELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFEATHPPILIDNGLAILENEKIERHIMKNIPGGYNLFVQDKEVATLIENLYVKLKLMLVKKDEAKNNALLSHLRKINDHLSARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQDIINHYKLQQSLKMKKHEELETPTFTTYIPIDISE
The following text describes a protein:
Function:
Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
Subcellular Localization:
Cytoplasm.
Sequence:
MLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGDVPHQEYVEHVLADLDADVPLVSGREISTIFIGGGTPSLLSAEAMQQLLDGVRARLPVASDAEITMEANPGAVEADRFSGYQRAGINRISIGVQSFSAQKLTRLGRIHGPDEARRAAELATSLQLRSFNLDLMHGLPDQTLEEALDDLRQAIALNPPHLSWYQLTIEPNTGFSSRPPILPDDDALWDIFQQGHQLLSAAGYLQYETSAYAKPGYQCQHNLNYWRFGDYLGIGCGAHGKITFNDGRILRTIKTKHPRGFMQGKYLDKQYEVAAVDRPFEFFMNRFRLLEAAPRADFYHFTGLTESTIRPQLDEAIAKEYLIETTEYWQITEKGKLFLNSLLELFL
The following text describes a protein:
Function:
Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Subcellular Localization:
Nucleus.
Sequence:
MPPRKRRKIDHKPKSSSKTSSQDNKDTPTYSHWLMKSEPESRIEKGIDVKFGITELKAEPNQTACWDGVRNYQARNFMRDQMRVGHKAFFYHSNCKEPGIAGIVEIVKESYPDHTQFDSKDPHYDSSSKKDNPKWFMVDVKFVRMLKRFIPLSELKALHLEHKSTGGALQNMALFTRARLSVQPVTKEEFDFVVSLEGKKK
The following text describes a protein:
Function:
Does not induce degP when overexpressed unless it is mutated to resemble YafY.
Subcellular Localization:
Cell inner membrane; Lipid-anchor.
Sequence:
MKRKTLPLLALVATSLFLSACDDRSDDLKAISKFKDLTPPRFSDVVSRQDDVSEEWSQVGFSSGLTLQVLRTRESPDGCEGGSYYYLVDMEEKTVQPLMNALCIADNIKLEYHEVTDPYTKEKYFEYSHDGKLMGRLLIPSNPDNRE
The following text describes a protein:
Function:
Catalyzes the formation of N-benzoylanthranilate, in the course of methoxydianthramide B, a phytoalexin. Phytoalexins are produced in response to infection by parasites, and are essential for the expression of disease resistance.
Sequence:
QLLKHISECFIKPKYEVHEAKQPYYLGPVDLAMLFAHYIQQGLLFTKPSNLGDEQFSIHELLQCLKKSLSLTLVHFYPLAGHLETQTDEEEGQKCLVFVDCNKGPGARFIHATLDMTISDILLPTDVPEVVQSFFDHDGAVNYDGHYRSLLTIKVTELLDGVFIGCSMNHALGDGTSYWHFWNVWSETHKAKLEESVPVLRMPIHDRWFPDGYGPPIFLPFTQPDDFVVSLHETPDQLRVRIFHFSSESIARLKSKANEETHNNNTTTRKISSFQALSALYWRSIIRALNLPHNQVTNCRLTTNNRHRLHPPLPKEYFGNCISALKTTTTVGELLEHDLGWAASLLHQSVINHGDKVVRDFINRWLKSPDIFKLEKLTDSYSVMMGSSPRFDMYGKEFGLGKAVAVRRGYADKFVGKVTCYPGYEGGGSVDLEICLTPDSMEALELDQEFMDNVSLFLKGYRIIE
The following text describes a protein:
Function:
Involved in the replication of mitochondrial DNA.
Subcellular Localization:
Mitochondrion.
Sequence:
MIKCGLTRLKSVRGASVRGYSDAARKQARNDTKWHEEPRLNPVGIQYMSHSLHKQLFGASESMRRRNLDEAARGKLVKWSKLYLKLHGLLGSKTSISEPISFELPQLQGTTLDEHFQRLGHFASDPYLSLCENKSTEILPRPQRWLRKAGWYRYAPGREPEAVASPLEDIYVFDVECLYKISDYPTLAVALSDKAWYLWCSPYICGEDNFVHLIPLNTMTRPQVIIGHNVGYDRSKVLEEYNLAPSKAFFMDTMSLHISSSGMCSRQRPFYLKNQKTKQQENDGDLDYELNEDLELGNWYNLSTMNSLRDVAKLHCNINLEKTLRDSFEALDKQEVIDKFQQLVDYCSTDVETTSKVFDKVYPLFREQCPHPVSFGALRFLSNCILPVQPKMWKQYIDGAETLYQNARQAIEEKIITIIEEIVKLKDKPEVYENDPWYKQLDWTISPLKLTKKGVPAKRQKMPGYPAWYRSLFTGTDKKPNITIRSRLIPLFFKLTWEGYPVVWNQEHGWCFEVPDANAGTFLKKNYAIANSPDFDRNVGYTAFRIPHPSSAEQRTTTLFSKPYMHFMDKNVLQSEYSLAREALKINSSGSYWTAARERIKTQHVVSKEDFPDQFAMVDGTPSRDDQVGAIIPKIIPMGTVTRRAVENTWLTASNAKANRIGSELKTKIVAPEGYSFVGADVDSEELWIASLIGDSVFNIHGGTAIGYMCLEGTKDAGTDMHTKTASILGCSRNEAKIFNYGRIYGAGVRFAAQLLKQFNPTLSEEQTRATAERLYEATKGKTYHSKIFKKFWFGGSESILFNKLEHIAEQDQPRTPVLGAGITVSLLKRNLGKDTFLPSRINWAIQSSGVDYLHLLFCSMHYLIEKYRLRARVCISIHDELRYLVANEDRYRVALALQVANLWTRAIFCEQIGIDDLPQNCAFFSAVDIDHVLRKEVDMDCVTPSNQTPVPHGERVTITDLLARPDAALNNPNPAVNVADYPVVQRQPVLAYYNSTYDAAFLNFFLDMQIQDSKASVADIEKHYREFLLRDAFSADRAETVTMADYLAANGGGKLSINAIDTTTLAPPQPQQRKPASRRKPRVINRSHRIAIGGPAAFDAFHASVDLAEEDADLRAAAITRNYLRDRPHL
The following text describes a protein:
Function:
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
Sequence:
MNQCGTITAVFEFEIKQRDGRARTATFQTPRGAVTTPMFMPVGTQGTVKGISPQELLEIGSQMILANTYHLMLRPGEQLVKAHGGLPGFTAYPGPFLTDSGGFQVMSLGHMRKISEEGVVFKNHLDGSRVELTPERSIQVQEALGADVIMAFDECPPYPAERPYIEASLDRTVRWLERCHAVKTKDDQALFAIVQGGVHEDLRLKSLEATLPFATPGFAVGGLAVGESKEEMYPAVAFTAGRLPENKPRYLMGVGHPEDLVAGVALGIDMFDCVYPTRTGRFGYALTDDGRLNLNSSAPRTQLQPIDAECDCYACRHYTRAYLAHLLRAEEMLAPRMLSLHNLRYLHRLVERMRVAINGQQFHPWAADWSERYFHGNVPGWFTSAFERSTQSEI
The following text describes a protein:
Function:
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MSTEPVSSLALPAPAILPTTPIPASTQQASSLVSDQIQEASTASQKSVTSITQPPIPSQQQPPQHITANHPASIAAAATVALSATLLNPNEWNALASTSMVTLDDLRSAFLEQRQQQLKDLERSHRESLREMIFMSENYDKEDVAGSPWKLGQSLQVAEDDAREHVKSFLDQHRLALDPKMSIKDHILEQPKLLRQRVSQELKTGPIELAPPPTPTSATAPSAGEAQRDRDLKREIEQNNLHRSQAVARAAAAVQAHAIAEGVAKIKPLTITAAESQGVRVAPLQPGQVPSFVIESTTPIAHIVASSDSSTAVLVASDAQKVDSHTTMSAAEAVTPAIKVESTDNIDASPSKASHALEKAVSPVPGLARNASTQSTSLRVPPSPMVVPTIPENITAPPLHPTLQVLAPNPLSVTYAASLRPLPPDPTRRITGAGLSGGAIHHRSGRKITSLSNHSNVNSYSSIAAAKIGPAGSGQADLYRWYVRARASPGAGMVGKADKCLMTSDWRVAFNEQRFVRAMARIEKLKAQGEWSFRQPKKQKGPVVRKAHWDHLLEEMKWLQTDFREERRWKMTVAFHLAHEVAAWHRARTPAERAQFCVHVQRSYRHRTISDNVEQHNTDKLSAKEVVSSSQPFQAAAASLDDVEMTHSTSSSHIQKDGEPATVKAESGQPVEDADVTMDGGADADEAVTQAVESALQTTNEAASARAEEMDADGEDDADTDANDVEAATAALVSGEPSKPPKVEVVREPLSQPQPMPTLADVSVPTTSSATPTVPASSTPTTAANDKLVHALRSQPKDADSTLTAEMPPQLLATLRAPIFSTSVTTTVVSPAALLDSLNPEAAAALLGIEVSDLANAADLLEPGSLSFSKMFPELPLYGGVSLPESNSKSDRRWDEGSLNQPPRLTHVTKLLDSRPLLVSTLEPSKNRANGRWLADSDWVVAAEQSDPLRGVTDGADTALPPMPGSLLFARKSNRAAKDASGPASTTPAEPASPDARAALFVWTPDEDNYLMTLAKQYHNNWALVADLFNSTRLNTATDKREAWDCYDRCKRIEQAAAEGKPPPGPPPMPAPAADADKDSKKGDGKDADASSSKRDKLSKKSGSKHDGSKRKQRRSNLMEVMRRSAKRREATKQAQQTQQTKKVNLNTHETHAQIKAGPAITPQSLSALKTERDQAALRQYYEQQRAQLAYQQQQQQQQRLLAQQAQAQRMAQQQGTAGTSAPAATAVTQAGKAGTAIVAGGTGGVGNVSLLPAGTPAASAGPAGQAQQKAATGQGTNQAIAQQTQQQQQQPQSQQTAQMQVQQPPAAAAAAQQQQQQQVQLQSQLQASQAAQMQNLYAQMQQQQQQQQRQQQQQLGQAAAGLAQVRPGVGALTQQQLATLTPQQQQQYHAQLAAATAAAQQQQLRSQMAAVAAAQGGQAGFQLPNAQAQAQAQAQAQFQLMQQQQQQQNVMQNQGRPAMAQQAQQAALQMYQQQQRQAQMRPPQPTQPFAARPNARPGTAASSQAKPQAAARSATPAPPMPATVQALQQQLAISLATSNLSAEQINGLAIQLYKQAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQQPAPTQQRPPPQQLLNQAIQALAAQTQKNQQPAPTVHGVTGSPVRPPTPRPS
The following text describes a protein:
Function:
When expressed in E.coli and M.smegmatis, HbO increases oxygen uptake. Membrane vesicles of E.coli carrying HbO show a respiration activity about twice that of membranes without HbO. HbO seems to interact with a terminal oxidase. Therefore, HbO could participate in oxygen/electron-transfer process, suggesting a function related to the facilitation of oxygen transfer during aerobic metabolism of M.tuberculosis.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MPKSFYDAVGGAKTFDAIVSRFYAQVAEDEVLRRVYPEDDLAGAEERLRMFLEQYWGGPRTYSEQRGHPRLRMRHAPFRISLIERDAWLRCMHTAVASIDSETLDDEHRRELLDYLEMAAHSLVNSPF
The following text describes a protein:
Function:
Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adaptor (By similarity).
Subcellular Localization:
Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane.
Sequence:
MVASNNMKGLRAFISDLRSLEHDDEEKRVNVELAKIRAKFQSSTLSAYDRKKYVSKLLYIYMLGYPITFGHMEAAKLLSGTKYSEKLIGYLAVALLLNENHELMKLVINSIKKDLLSHDSLQNSLALHTIANIGGRELCETVYYDIYKLLMSASNENIVRQKSALALLHIYRKFPDLINPEWFEPIVMILGDDDLNVSLAVSNFVNLIVIREPKYQKFAYGKAVGKLKNIVFEHGYSSDYLYYSVPCPWLQVNLCRILLACERPSDNPTRATLIRVLDRILSLPNDNSNVQQVNAVNAILFEAIKLAFLVDESHSLYEKCMDRLADMIADKESNIRYLAFETTAYLISCGHSITSLKHYKELILSSLRYKDVSLRKKSLELLYMMCDEENAKLIVADLLQYLPHLDSVTQEDLISKVAIISETFATDYEWYVDVTIQLLRIAGKSADDGVWHQLVHVIVNNEEIQEYATKRLFSLLQSETIHECLVKAGGYVLGEFGHLITDYPDSQPVHQFSTIYRKLNVSSPSTRVLLLTTLIKLANLQPELNDRIAKVFQEYSTIINPEVQQRACEYLQLLKMPRDFLQLVCDEVPPFLDGNRDGVHPKSRPSSKVNLVDTYPQTIPNVSKPSTPIDVPEYDISACLPGFYRLCWKDKGILYQDSQIQIGVRSEYHNSEGAIYLYYENRQSNTLKSLSSTLIRTFSTFHLATTFQDTNLPSGVQLQQKYVMSGVNEIFEPPIIHVSYVTGVIRSIDLQLPVLLSKFMKPTIFDSYDFFNHWGQMGVEREAQLTFGLNSKDRKLDAKRLTKIVSGFHWGICQNVDSIALNIVGAGIIRFGTQNVGCLLRIEPNYEQNLIRLSIRSTNTSIANTLAKEMQEILRNSF
The following text describes a protein:
Function:
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
Miscellaneous:
MISCELLANEOUS: In the RecBCD complex, RecB has a slow 3'-5' helicase, an exonuclease activity and loads RecA onto ssDNA, RecD has a fast 5'-3' helicase activity, while RecC stimulates the ATPase and processivity of the RecB helicase and contributes to recognition of the Chi site.
Domain:
The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA; The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.
Sequence:
MSNSPVTDPYLHLPLHGVRLIEASAGTGKTFTLATLFTRLVVERQLRIGQILAVTFTEAATQELRRRIRERLALAATLVPDARAGAAATEAQTTLLPDASSAGVGAALAATEPTQTQASDAPSSAINMVLPATAPSDHLSHPPAQTPPQPHAPAAPDAVLTRAILTAHLATGTETPSALRRRLQQAVEEIDLAAIFTIHGFCARVLREHALESGQAFAAPQLLANDRELLGEVAADLWRQRAADAAMAADLVALWPAGPTALASDLRALVQQPELLPAVAAPTPDPQPARQAAAQAVVAALRAHGDTAYDAVAAAFEHKIFDGRRARRPSFDKAFEQLWQGSAEAHWVLDDGGHLDKLLPQRLREFCKDGAHDRVPCSPLFDALAVWQQADAVVRQWEGQRRIRLLHALRDDAVLQLAQRKRQRRVQTYDDLVDGVARALQGPQAEALVQRLRAQYAIALVDEFQDTDDRQWQIFSRVFGPEHGASGAAFAPDDDADFDNAAGTPPPRLLALIGDPKQAIYGFRGGDVQTYLAAATTAQRAPPLEHNFRSRPGVLAAIDALYAQAGYAEAFLTEGIAFHPVQPGTKRSDADLQRDDAAAPALTLWRAPAPPPPAKGKPKPWSAGRARELCTAACVAAIRGWLAGGRDGSASINGRPVQAGDIAVLVRSHGEATRIQQALGAVGIPAVAAGKQSLFATDEALELLALLQALLDPGDDSRLRAALATVLIGEDAAAIAALEHDGERHRRWQQQALDWRERWQRGGPLALVGDLGATHGQRLLALVDGERRLTNYLQLAELLQEADTRALGPHGLVDWLARRIANADDNDETQQLRLESDARRVQIVTLHKSKGLEYPLVFLPYIGIGRADKSPGRHCVVHAPPHGRQLHWNTSKWSADDTASWSTAETAWKHEQRAEDARLLYVGLTRAEHALWIATGAFHQHERTALAPMLRDPAALQASAGAGVIALDDTAPPATLPRLPADDAVQVPAARLAQRHVVPDWWVYSFTQLANADAGSDPMASATLASSGGSDEPPASEPVSAPAEVEAFDPRFAGNRFGVAMHDVFERCDFAAWRNWCPGQPAPEGQAAAILEALQRGGYAQDELDDGLAMLTRLVGHTLTVTLPEGTCLAAVPEPQRRNEMEFHFAMRPTRVDALLALLHRFGVVTERQAFGARQRLEGLMTGLIDLTYCADGRWYVLDYKSNRLPAYDPDALARAMAHSEYELQALIYTIALHRWLRFRLGASYDYARDFGGVRYLFCRGLDAARNPAADSSSILGSGSGSGSDSDSDSVNGASSVSGSDPASDAMSDTPAPNTPVPGIYAWRFDPALVQALDALFAGNPTEPLSSDALKPLSPRERGWGEGTSTTGTPTP
The following text describes a protein:
Function:
Required for proper function of the olfactory system. May be involved in establishing the acuity of olfactory sensory signaling.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type I membrane protein.
Sequence:
MQPFSPIFFHLLFLLNGLSSRAAPSPGQPVVADLQGMLQPSGMPTGTLENLTRDQPTPGSSASHPPEHSETPPSASPHISTKILRETPSPSPFLSLETPIPDQLTSVAESQGTSQMSPSRATLGKPSETPKPDPTGISPSDSPETPKPNPSNTSPPESPESVYTDPTPTLHHESPEISKRDTPKLSPGEESKIPSPRPTQFLSSKSLETYDPSATRHLNSALEPTTHPDPTESPQSVFLTTHNSNPTVVPQTQFPTSPSQNVTETARTSDLEPSSSLPTQPTTFREEATTPSEPGLSPSPEAPAVTRVATPGLSTSDSPGTKELHVPQNSDPKGPDIPLPSARIAGPPAPLEHPNQVAPAPQRHSRGDTVNTIIVVERVKETGVTLVSRPRGSVGGALCLFFAGTGLLIGIFLLLWCLYRRASRHRSFAHHRLRDSGDEPVLHLDAPKDPLDLYFYAPDAWVPSHIATQPPPSTPPLPPKLPPPPRGPQRLEALSPAALSPNFF
The following text describes a protein:
Function:
Mediates the NAD(+) import into peroxisomes. Favors the NAD(+)(in)/AMP(out) antiport exchange, but is also able to catalyze a low unidirectional transport that might be essential under special conditions. Transports CoA, dephospho-CoA, acetyl-CoA, adenosine 3',5'-diphosphate (PAP), NAD(+), AMP, ADP and NADH, but has no activity with ATP, GTP, GDP, NADPH, NADP(+) or FAD. Required for peroxisomes proliferation.
Subcellular Localization:
Glyoxysome membrane; Multi-pass membrane protein.
Sequence:
MSDALINGLAGAGGGIIAQLLTYPLQTVNTRQQTERDLKREKRKLGTIEHMCQVVKQEGWERLYGGLAPSLAGTAASQGVYYYFYQVFRNRAEATALARKKKGLGDGSVGMFASLLVAAFAGSVNVLMTNPIWVIVTRMQTHRKMTKDQTAAPESPSSNAEALVAVEPRPYGTFNTIREVYDEAGITGFWKGVIPTLIMVSNPSMQFMLYETMLTKLKKKRALKGSNNVTALETFLLGAVAKLGATVTTYPLLVVKSRLQAKQVTTGDKRQQYKGTLDAILKMIRYEGLYGFYKGMSTKIVQSVLAAAVLFMIKEELVKGAKLLLSNATSS
The following text describes a protein:
Function:
Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB (By similarity).
Sequence:
MILLIDNYDSFTWNLYQYFCELGAEVQVRRNDALTLAHIDALNPQKIVISPGPCTPNDAGISLAVIRHYAGRIPMLGVCLGHQAMAQAFGASVVRAAKVMHGKTSPVTHNGQGVFRGLPSPLTVTRYHSLIVDPATLPECFEITAWSETQEIMGIRHREWDLEGVQFHPESILSEQGHALLKNFLRR
The following text describes a protein:
Function:
Putative tyrosine-protein phosphatase required for protection against superoxide stress.
Subcellular Localization:
Cytoplasm.
Sequence:
MTDNCREDDDNLGTSGDNALSAPTQLLVTPPAPHQTIVPPLNFCPVERYLYRSGQPSTVNFPFLLNLNLRTIIWLANEEPQDALLAFCDMHDIRLRFAAINPEGGEDDNPWDGLTEHSIVSALQTIVHRDNYPLLVCCGMGRHRTGTVIGCLRRIMGWNLASVSEEYRRFTGSRGGRILVELLIEAFDTKSVTIDKANAPEWLATAVSASEASYVPATTYSIHEM
The following text describes a protein:
Function:
Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
Sequence:
MSAILSADDLNDFISPGVACIKPVTQPKSELNPQHVDSSSTISETGEVEIQIDSQGNPLEISQIDTKINKADPSSTALTPAQISLADCLACSGCITSAEEVLVAQHSHHELLKAMEESSLASGTEKVFVASISQQLRASLAMAYDMSIEEMDKLLINLFVNQMGFQYVVGTSLGRKLSLINESQGMIHRKEEGKTIGENLKNPVLSSICPGWVLYAEKTHPYVLPYISTVKSAQQITGCLLKNLTAYERGIGKSKVYHLTIMPCFDKKLESARPELFANHDGADNVPDVDCVLTARELVTLIDESLGKYQLVPKVIPQTLLRKDIAEVYKSAAPTNWPFVQYSWSNDPGSSSGGYAYTYLRLFQEQLITTQNYRPEDFSMKVLQGKNTDVYEMRLLHNGNQVASSAIVNGFRNIQNLVRKLKPGNNNNKVGGLAIKVNPLVARRRARMSKSEDSSGASASSMAPAEIADPSKVDYVEIMACPQGCINGGGQIAAPAPTSTPPAAPAPAHAATSTTDVKIAVVLNKDWVSEVLMKYNSVPMFDLSLHPEEIAGFIQWSQEFEKEFDVSEQRLFKTHFNEIEKPTDATAIMVGSKW
The following text describes a protein:
Function:
Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2.
Subcellular Localization:
Cytoplasm. Cell projection, axon.
Sequence:
MDNYTVLRVIGQGSFGRALLVLQESSNQTFAMKEIRLLKSDTQTSRKEAVLLAKMKHPNIVAFKESFEAEGYLYIVMEYCDGGDLMQRIKQQKGKLFPEDTILNWFIQICLGVNHIHKRRVLHRDIKSKNVFLTHNGKVKLGDFGSARLLSSPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCALKHPFQANSWKNLILKICQGPIHPLPALYSCKLQGLVKQMLKRNPSHRPSATTLLCRGSLAPLVPKCLPPQIIREYGEQILDEIKISTPKNMKKQDSNRVRRALGEANSASMQEEERGRKCSHTELESTGTTPAGNALERAARGNPESGNPQEHGRHTSPASPHRPWWERHGPSSNVEALEKASILTSSFTAEDDRGGSVIKYEENARRQWVREPPEALLSMLKDADLSQAFQTYTIYRPGAEGFLKGPLSEDTASDSVDGDLDSVMLDPERFEPRLDEEDTDFEEDNENPDWVSELKKHVGYGDGPGGQLLGERA
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.
Subcellular Localization:
Cytoplasm.
Sequence:
MAETGQTTSKPEHLEPSKLGTKEYWDALYDTEIANHETNPSDIGTVWFDDSDAEAKMVSFLNTKRVDLSLDRNSTSFVDLGTGNGNMLHALRRAGWAGPCLGVDYSPAAVALAQKVAASTTYSEASDEDDEEHESEKRDPSNNPISFAQWDVLDGPLDPDAAATPRRGAWDVVLDKGTFDAVCLSADIDAATGRRRSEDYRARVLELLRPGDGGVFLVTSCNWTEEELRAWFEGRGGEGAARLVYADQVQYRSFSFGGVKGQTISTVCFVKKDSTS
The following text describes a protein:
Function:
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
Subcellular Localization:
Cytoplasm.
Sequence:
MNEALPDDFDVIIIGTGLPAAVVSGALSRVDKKVLHLDRNDYYGGSWSSFNIKSVETFLQNPYDSAEYLNKDGEETSNIEVSEDEEFVPILQNKNFITKAEYSCYLKRSEKNEEPAQSSSPCVDTCQSDVVEQSCASKPDDSLKSGETPISEEVQKREESPKVENCNDPATQGDGDSVEKEKELTQELDKAKTKEKVDVSEVVKPRFPLSEDFYKQWRHYNLDLSPKVMFSRGLLVELLIQSNVSRYLEFRNVTRTLTFLDGSKELQRVPCSRADVFSSKFVSVVEKRILMRLFTLCANYKDHEQEYQNFREKTFIEFLASRRLSLKAQHFVLYSIAMVSETTSTLDGLAATHKFLHSLGRYGNSAFLWPSYGVGEIPQAFCRFSAVFGGTFCLRRYAVGFIKDKTTGRCTAIVDNTGQKIRCGTLILDDLNLPHGANTTSTSSVDRAIYVIDSTVSKSDAEQEVSLVTIPPMCDNPAVRLIEAGPLCCVCPKNNYYCTKKNCEKQPKKLPFKKNVKNCLNLDETNIKPEVGGEDSQSRKPVILWSCHFTMTDTNTDNSTLPPNVITLQGPRMDLGFDRAMNEAREVFLRICPGEDFLPRAPDPEEIVFDEGYNTENNDTISPTPEDGGGDYVEEEEEDLNEPAAE
The following text describes a protein:
Function:
Degrades NAD into adenosine and nicotinamide riboside, the latter being subsequently internalized by a specific permease. Also endowed with NAD(P) pyrophosphatase activity. Exhibits a broad substrate specificity, recognizing either mono- or dinucleotide nicotinamides and different adenosine phosphates with a maximal activity on 5'-adenosine monophosphate.
Subcellular Localization:
Periplasm.
Sequence:
MLLSKKSASFALSAFAMLFTSVALAKEAPQAHKAVELSILHINDHHSYLEPHETRINLNGQQTKVDIGGFSAVNAKLNKLRKKYKNPLVLHAGDAITGTLYFTLFGGSADAAVMNAGNFHYFTLGNHEFDAGNEGLLKLLEPLKIPVLSANVIPDKNSILYNKWKPYDIFTVDGEKIAIIGLDTVNKTVNSSSPGKDVKFYDEIATAQIMANALKQQGINKIILLSHAGSEKNIEIAQKVNDIDVIVTGDSHYLYGNDELRSLKLPVIYEYPLEFKNPNGDPVFVMEGWAYSAVVGDLGVKFSPEGIASITRKIPHVLMSSHKLQVKNAEGKWTELTGDERKKALDTLKSMKSISLDDHDAKTDMLISKYKSEKDRLAQEIVGVITGSAMPGGSANRIPNKAGSNPEGSIATRFIAETMYNELKTVDLTIQNAGGVRADILPGNVTFNDAYTFLPFGNTLYTYKMEGSLVKQVLEDAMQFALVDGSTGAFPYGAGIRYEANETPNAEGKRLVSVEVLNKQTQQWEPIDDNKRYLVGTNAYVAGGKDGYKTFGKLFNDPKYEGVDTYLPDAESFIKFMKKHPHFEAYTSSNVKFNASTDALPKK
The following text describes a protein:
Function:
Induces the expression of gadE and mdtEF. Could also regulate the expression of other genes involved in acid resistance.
Sequence:
MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPYERHFKEIGFTENTIKKYLQCTNIQTVTVPVPAKFLRASNVPTGLLNEMIAYLNSEERNHHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKPAHPWKLKDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYAFRKHFGNSPKRVSKEYRCQSHTGMNTGNTMNALAI