lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state. RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain. ZUO1 can act as a J-protein for SSB1/SSB2 only when associated with SSZ1.
Miscellaneous:
MISCELLANEOUS: Present with 86400 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MFSLPTLTSDITVEVNSSATKTPFVRRPVEPVGKFFLQHAQRTLRNHTWSEFERIEAEKNVKTVDESNVDPDELLFDTELADEDLLTHDARDWKTADLYAAMGLSKLRFRATESQIIKAHRKQVVKYHPDKQSAAGGSLDQDGFFKIIQKAFETLTDSNKRAQYDSCDFVADVPPPKKGTDYDFYEAWGPVFEAEARFSKKTPIPSLGNKDSSKKEVEQFYAFWHRFDSWRTFEFLDEDVPDDSSNRDHKRYIERKNKAARDKKKTADNARLVKLVERAVSEDPRIKMFKEEEKKEKERRKWEREAGARAEAEAKAKAEAEAKAKAESEAKANASAKADKKKAKEAAKAAKKKNKRAIRNSAKEADYFGDADKATTIDEQVGLIVDSLNDEELVSTADKIKANAAGAKEVLKESAKTIVDSGKLPSSLLSYFV
The following text describes a protein:
Function:
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.
Sequence:
MERKPPIIIEPMSPVDPSKAAAFVFVHGLGDEAEGVENVARQFQNAGKLPYMTWVLPNALENNDLATTAWYMPTSLSPYPPSRPELEDDEDEEGMLATVKYLTSLIDDLVKQGIPEKRIVLGGFSQGHAMSLLGGLTSKYASKLAGLVGLSGYLPLPDRIPTLREEAGLPKEIKDEVEVFLARGTGDRLVPKRYHRLCYEKLFELGVPEERVTLKEYEGLGHVLSGAELRDLCTWLERVVPPL
The following text describes a protein:
Function:
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. In addition to axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses (By similarity).
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite.
Sequence:
MGPLWFCCLPLALLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKYIRRRGAHRIHVEMKFSVRDCSSIPNVPGSCKETFNLYYYESDFDSATKTFPNWMENPWMKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSKNGFYLAFQDYGGCMSLIAVRVFYRKCPRVIQNGAVFQETLSGAESTSLVAARGTCISNAEEVDVPIKLYCNGDGEWLVPIGRCMCRPGYESVENGTVCRGCPSGTFKASQGDEGCVHCPINSRTTSEGATNCVCRNGYYRADADPVDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQFAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKNLSELNSTAVKSPTNTVTVQNLKAGTIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSVQEKLPLIIGSSAAGLVFLIAVVVIIIVCNRRRGFERADSEYTDKLQHYTSGHSTYRGPPPGLGVRLFVMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGVNLPLLDRTIPDYTSFNTVDEWLDAIKMSQYKESFASAGFTTFDIVSQMTVEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQSVEV
The following text describes a protein:
Function:
Binds and exchanges GTP and GDP.
Sequence:
MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN
The following text describes a protein:
Function:
Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP (By similarity).
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
Sequence:
MNWAAAVCWALLLAATFLCDGSAAKGGRGGARGSARGGRGAARVRVRPAPRYAGSSMRVAAGAAAGAAAGAAAGLAAGSSWRRAAGPAELGPEDAEDGAPGSNGTGRGVYSYWAWTSGTGPTGHRHLCPLLGGALGALRLLRP
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Sequence:
MKISLHNKRQRGDQNQNMSVFNVLKPLLKGSNSFKVKLNGFLFNNVSTITIRTLMKTHKGTAKRWRRTGNTFKRGIAGRKHGNIGWSHRSLKALTGRKIAHPAYSKHLKRLLPYH
The following text describes a protein:
Function:
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
Sequence:
MESEESEQIQEVEEESQDSQELAEIPVHLDDSSVSYATLSLSNSSSNIVRGKYYKQTYRPAWEQMPDFKGWLRGVVGEPTRAYCTYCQKTLHAHRLSLLKHTCTIRHQKAAQIHNNRKVGKRSVHRNKTQNMETQEIHAVVLQESDLNQTEIDNEDGDTIEYTEVTSEVEDEENAQKDGFDQEIVEEEEEEESTMELHQVTFEKHNQNFQGNQSKSPISTHVIDTTRGVPVSGLQVSLYKLIDGRWTYINEGVTNLNGKFGGFVDRADFSTGRYKLHYDVDRYFEARKQDSMYPFIEVVFDCRAVTENYHVPVILSPYGYSTYRGS
The following text describes a protein:
Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Subcellular Localization:
Plastid.
Sequence:
MAISSTAAATAASSKLRYPHASPFPTHSSTTTSAFFSSIPSKLTPTHLSSSFLPPFLTTVATTYVFPRRRDSFTVKAARGKFERKKPHVNIGTIGHVDHGKTTLTAALTMALASMGNSAPKKYDEIDAAPEERARGITINTATVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSGADGPMPQTKEHILLAKQVGVPNVVVFLNKQDQVDDEELLQLVELEVRELLSSYEFPGDDVPIISGSALLALEALMAKPSIPRGENQWVDKIYELMDAVDSYIPVPQRQTDLPFLLAVEDVFSITGRGTVATGRIERGTVKVGETVDIVGLKDTRNVTVTGVEMFQKTLDDAMAGDNVGLLLRGVQKADIQRGMVLAKPGTITPHTKFSAIVYVLKKEEGGRHSPFFAGYRPQFYMRTTDVTGRVASIMNDKDEESKMVMPGDRVKMVVELIMPVACEQGMRFAIREGGKTVGAGVIQSIIE
The following text describes a protein:
Function:
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MKIDPIHQFNIEPLFTIGHIGHQTIAFTNSSLYMLIAVAIISLLMLASGAQLVPGRLQSVAEISYEFVASTIRSTAGSEGMKFFPLIFSLFMFICVSNLIGIIPYTFTISSHLIVTAALALLVFFTVLIYGVAKNGLKFFSIFVPHGVPGYILPLVMFIEILSFFLRPVSHSVRLFANMLAGHIALKVFAGFVAMLGFSLGALGWVGGVLPLALTVALYALEILVAFLQAYVFAILTCIYLNDAIHPGH
The following text describes a protein:
Function:
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MRRSVLRAIESAKPLARVPRSASRSFATLNESKDPAELDQITTLPNGIRVATESLPGPFAGVGVYVDAGSRYEDESLRGVSHIMDRLAFKSTKSRTSDEMLETLESLGGNIQCASSRESLMYQSASFNSAVPATLGLLAETIRDPLITDEEVLQQLATAEYEINEIWAKPELILPELVHMAAYKDNTLGNPLLCPRERLEEINKAVVERYREVFFKPERMVVAFAGVPHEEAVKLTEQYFGDMKAANQAKGPVLSGTGIETTLSDSETAAQEGQVPTVPQFTPSSTITTTPTSKTQSVLSRLPFLKNLSTTASKPASVAPLDPSLVQPSSLDLTRPSHYTGGFLSLPPIPPPANPMLPRLSYIHLAFEALPISSPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTNVLNQHGWVESCIAFNHSYTDSGIFGISASCSPTRTTEMLEVMCRELQALTLDTGYSALQPQEVNRAKNQLRSSLLMNLESRMVELEDLGRQVQVHGHKVGVKEMCDRIEALTVDDLRRVARHVFGGHVQNKGQGTGIPTVVLQEGELEGYKLRPFPWEEIQERIARWKLGRR
The following text describes a protein:
Function:
Putative oxidoreductase.
Sequence:
MVVGSLLLFIGFPYIVLKSVLSVLFTFLTVYYIVDQFLLPKLREKPLSSYKGKVVIITGASGGIGEECAKQYARLGSKVVLVARRTEQLNRVKENILKNYSRVKDEDLLVVKADLTIQDDCKQMVQTVIDNYSKIDICVWNAGLGSLIEFSKLGDDIQIYRDNMEINYFSLVYCTHLVFPYLIQSKGSIVVISSLAGKFGTALRTSYSASKHAVQGFFNSLRHETKDIQITIVNPGFILTEFHDNLKTLDGNKVERNKGNFMTAERCAAEILEAERQRRRELIQSAKGKFGVIVQNIAPDLVDFLSHKFASSSVKK
The following text describes a protein:
Function:
Plays role in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MSYALNSLQSKRDVDRAVKETIDKVLVLRFGKEDSLECLRIDEILRKTAPLLSRMADIYVVDSQSVPVYTRYFDISITPATLRKTAPLLSRMADIYVVDSQSVPVYTRYFDISITPATVFFFNGQHMKVDYGTADHTKFIGCFKTKQDFIDLVEVIYRGAMQGKLVVTSPIDPAHINKYDLLYMDI
The following text describes a protein:
Function:
Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes. Induces expression of a number of antimicrobial peptides including beta-defensins 4 and 103 as well as a number of matrix metalloproteases. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinocytes induces the expression of macrophage, T-cell, and neutrophil chemokines, such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CL20, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20 and CXCL1, and the production of pro-inflammatory cytokines such as TNF-alpha, IL-8 and IL-6.
Subcellular Localization:
Cytoplasm. Secreted. Note=The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Sequence:
MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGNMVYLGIKGKDLCLFCAEIQGKPTLQLKLQGSQDNIGKDTCWKLVGIHTCINLDVRESCFMGTLDQWGIGVGRKKWKSSFQHHHLRKKDKDFSSMRTNIGMPGRM
The following text describes a protein:
Function:
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MAEQTGGGGCCPPMDLFRSESMQLVQIIIPNESAHRTIDYLGEIGLIQFKDLNAEKSPFQRTYATQIKRCGEMARKLRLFKEQMSKAGLLSSSMSSTQVDLSFDDLEVKLGDLESELIEMNANGDKLQRSYNELMEYRLVLQKSGEFFHKAQSSAEAQHREQASHQTGEQSLETPLLSDQDAVTDPSKQVKLGFITGLVPREKSMAFERILFRATRGNVFLRQTVVEELVIDPVSGDKAEKNVFAVFFSGERAKSKILKICEAFGANRYSVPEDLGKQAQAITEVSGRISELKMTIDAGLLHRGNLLQSIGEQYDRWNILVRKEKSIYHTLNMLSIDVTKKCLVAEGWSPVFATKQIQDALQRATHDSNSEVGAIFRVLRTREMPPTYFRTNKFTNSFQEIVDAYGVAKYQEANPGVYTIVTFPFLFAVMFGDWGHGICLLLATMYFILKEKKLSSQKLGDIMEMTFGGRYVIFMMSLFSIYTGLIYNEFFSVPFELFGQSAYGCRDPSCRDSTSAGLIKVRDTYPFGVDPAWHGTRSELPYLNSLKMKMSILLGVAQMNLGIILSFFNALFFRNGVNIWCQFVPQMIFLNALFGYLSVLIIVKWCTGSKADLYHVMIYMFLSPTDELGENQLFAGQKITQLVLLLSALVAVPWMLFPKPFLLKAQHERHQGQSYTALQEAEESLMVENNDDSGHHEEFEFSEIFVHQLIHTIEFVLGAVSNTASYLRLWALSLAHSELSSVFYEKVLILAWGFNNVIILIVGIIVFIFATVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFSPFSFTLIDGEDE
The following text describes a protein:
Function:
Required for vacuolar assembly and vacuolar traffic.
Subcellular Localization:
Vacuole.
Sequence:
MQTSSPVKMPDDNAMEGAETQHEGGNVENPPTGEEVIPQSRGSDYNTARDTADTSTTTANNEVDEATETNGNDTSNGSGDNSSGKKDTEGHSDDNEAQNGEGSDKHGQEDTQEEEGNDEQNGKQNDDHKSDHNSESTNSESESDSDSGSDSESDSDSDTEEAEPRLKYSRLAGLPKTIFTRDPVSATLVNDNIVIIATHSGLIHLFRPNIELIRSFKAHSASIMSLSTDGTYFASASLDGRVVIGSISDPQDIAASDFKRPVHAVALDPNYASSKTFVSGGTAGNVVLSEKGWLQARSDTNICTSDSTIVLLRWIGDVVLWINDDGITIWNHVTKQQVLQVPKPDNISRADLYHPRMHLSDGHDRIYLAWADHIWILEVTQEKKERGKRLKKEPVNDGMSIFSRRILSTSASSTKSPQPETTVAVVTKFRVDSLLCGISTFGADMLMLLCYTKGERRAQRPELRLIDAASGEEVSSDELPLNGFESLGPNDYQLQTHAPVQKDAKAQYYIISAHDGVVARERDLTDHVQWLVEHEKYESAWVTCESIYGTVERKNLGIEWVESHVRDELWREAGAALSLVLTAFLGTIDPQDTYKHTIWSEDWANWAFIFGKSNNYELLANYLPDQLQSSVYDEYLRHYLRDDAEKFGFYMKKWQGLFGEGIEQSLVEEIDSSEDDKKTSALKLALAELNIADGKYKPALALLLELRDERCLDLIEAHHLLSDISPKDIPSLLTIGAGKDTASTLAALDKASAEEIQTTLKRTTELLVEGYHELPPKTVLSSLPESSPLAYVYLHSLNQVDSFAARDYGNQLMALYAKYDHVALSAFLKSNNNYDIGSAVDLCRADKSLTPDLVYLLGKVGRNMEALRLIIDELQDPYQAISFSLKQKDSELWNFLVDYSIDKPLFLKALLENIAMAQTPTYKLIERIPPNLEIPGLKGCLLNIFTENELQLSVTKGAHEIITNECHRETDALGRLRMGGVAFDGVGMDEFAVKSLDGKTVEVDSLPSWQAHDGSFASKLAHVSFLQQQSGR
The following text describes a protein:
Function:
Probable CoA-transferase.
Sequence:
MLDLSDGCSAGGTDMVTRLLADLGADVLKVEPPGGSPGRHVRPTLAGTSIGFAMHNANKRSAVLNPLDESDRRRFLDLAASADIVVDCGLPGQAAAYGASCAELADRYRHLVALSITDFGAAGPRSSWRATDPVLYAMSGALSRSGPTAGTPVLPPDGIASATAAVQAAWAVLVAYFNRLRCGTGDYIDFSRFDAVVMALDPPFGAHGQVAAGIRSTGRWRGRPKNQDAYPIYPCRDGYVRFCVMAPRQWRGLRRWLGEPEDFQDPKYDVIGARLAAWPQISVLVAKLCAEKTMKELVAAGQALGVPITAVLTPSRILASEHFQAVGAITDAELVPGVRTGVPTGYFVVDGKRAGFRTPAPAAGQDEPRWLADPAPVPPPSGRVGGYPFEGLRILDLGIIVAGGELSRLFGDLGAEVIKVESADHPDGLRQTRVGDAMSESFAWTHRNHLALGLDLRNSEGKAIFGRLVAESDAVFANFKPGTLTSLGFSYDVLHAFNPRIVLAGSSAFGNRGPWSTRMGYGPLVRAATGVTRVWTSDEAQPDNSRHPFYDATTIFPDHVVGRVGALLALAALIHRDRTGGGAHVHISQAEVVVNQLDTMFVAEAARATDVAEIHPDTSVHAVYPCAGDDEWCVISIRSDDEWRRATSVFGQPELANDPRFGASRSRVANRSELVAAVSAWTSTRTPVQAAGALQAAGVAAGPMNRPSDILEDPQLIERNLFRDMVHPLIARPLPAETGPAPFRHIPQAPQRPAPLPGQDSVQICRKLLGMTADETERLINERVMFGPAVTA
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MSDNKEIPSEYRISEKWDKCLENFTLYFGAGLVAGGLTSLVLARSGAGRGLVTGLGAGVGAGSSWTTCQLAFAGDANAQAALDKTDKAVGDFKEKISGSN
The following text describes a protein:
Function:
Has a role in the control of cell polarity and cytokinesis. Involved in bipolar growth and septum formation.
Subcellular Localization:
Cytoplasm. Note=Septum.
Sequence:
MSNPRMFQSRGKRVVSDSLPIANSTHTLEDTLKLRPDWTIALSQHETETRSTRTSCSTTTESTIAMRSKQKAIISVLEEFRDSEAAYVHDLHVAQRYYADRLSDRVKKSEWKDVFEIFLVLCKQASLFEIEMHKSLNDEINYILDDQDACLKPKPSVAQLFLSWLPKLSAVYGRYCVIQENIGKKVEKWMKNSSISEYLQECDSMAKIESNSWNLDSFLVKPVQRFLKYPLLLNQLYRSASLGIISDYVLLGEACHKSEIASQRMNELKRRRDIIITALDSVSNSQEVLLLSTDSIDKKIAKLQNSTNIFYVPEHEPILAFVHQLSSSYTNLLNLRSAICDWLKFSRYHYLKFFTFVEAYSVFCKDTKSADKWALISVALDNIAKGAVLRLTEQCQTSVLRPISNGILFFRNPLCVTDVWIKKATAFSKRRQSQVFEEDLESFPLLSNCLLEELPLFLEMARNVTDECILAFAQIQATFYDTIQKVLEPVVAKFNLTDHQDIPSIESIMDFTSLRSSMESSPKSK
The following text describes a protein:
Function:
Component of the transition zone in primary cilia. Required for ciliogenesis.
Subcellular Localization:
Cell projection, cilium. Membrane; Multi-pass membrane protein.
Sequence:
MKVIESLYLTPSFILSGVTKSPRVRRSVSEEGIDEIPDSSGKKRRKPKPRPEGEGEGSAEGEGEGGEKARPPRPQPGKKKKKKNARTALNSADEAYQADGEVSVDFMVADEDIIVGDKTTDVQKPHKVSSMTSQPVGPLFVETKSGFRVEQRRRLSRLQETDEEYAEQNKADRTTGELALSTHRGFKKFALFCHGILAGYSLWHCIVVFLLTEKGDLNFLQQYSRLAQPAQSLFYLLLAICTVSVFDSYDVARPNRRFFRSLLTPQSGAISILVYLISIIFSVSIASIDDRIGLFVDAAPTIMPSDVSTATVATTNQNLWTDSDAANRLYIWRIINTMRVGGAILGWLIVALNPTVDHTSEHLYDPEDSLVATEMVPRNPVA
The following text describes a protein:
Function:
Involved in pre-mRNA splicing.
Subcellular Localization:
Nucleus.
Sequence:
MRLTVELIQNSLSYINPLKDRELDLRDNDISSLGNFPFFPRLRMLLLARNRVRQIQPSLANSIPGLTTLVLTANNIAELADLDPLRNLTKLTHLVLLENPVTRKEYYRLWIIWRIPSVRFLDYQKVKDAERAKAAELFGTATEPTALASKILGVKSRTFDIPSGGAADQPPPEKRLRVKLTDSERKRIEKMIREAKSLQEITRLERELNEGRIPGGALDGAGNDGDQMQL
The following text describes a protein:
Function:
Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSNSSGEKSEKPTAGKLSKARKKGDIPRSKDVTMAAGLVTSFILLSLFLPYYKALVSQSFVSVAQLASQLDDQGALEQFLLANLFIFAKFLATLIPIPLFSMLATLIPGGWNFTPVKLIPDLKKLSPLAGIKRIFSASNGTEVLKMLAKCSIVLYTLYLVVHSSLDDLLHLQTLPLEEAITQGFAQYHHILLYFIAIVVVFAAIDIPLSHHLFTKKMKMTKQEVKQEHKNNDGNPEIKSRVRQLQRQYAIGQINKTVPSADVIITNPTHFSVALKYAPEKASAPYIVAKGKDDIALYIRSIAQKHKIEIVEFPPLARAIYHTTKVNQQIPAQLYRAIAQVLTYVMQIKSWRSGQASKPVLNTHLGLPKEMQRFHDET
The following text describes a protein:
Function:
Plays a role in host nuclear actin polymerization by recruiting p78/73 protein that is capable of activating an actin-related protein 2/3 complex to initiate nuclear actin polymerization.
Subcellular Localization:
Host nucleus. Virion.
Sequence:
MSAIALYLEINKLRLKIDEPMQLAIWPQLFPLLCDEHQSVQLNTDVLINFMMHVARKSQNTILNNNAAIASQYAAGNADVVAAPASAQPTPRPVINLFARANAAAPAQPSEELINMRRYRNAARKLIHHYSLNSTSSTEYKISDVVMTMIFLLRSEKYHSLFKLLETTFDDYTCRPQMTQVQTDTLLDAVRSLLEMPSTTIDLTTVDIMRSSFARCFNSPIMRYAKIVLLQNVALQRDKRTTLEELLIERGEKIQMLQPQQYINSGTEIPFCDDAEFLNRLLKHIDPYPLSRMYYNAANTMFYTTMENYAVSNCKFNIEDYNNIFKVMENIRKHSNKNSNDQDELNIYLGVQSSNAKRKKY
The following text describes a protein:
Function:
Cytoplasmic uridylyltransferase that mediates the terminal uridylation of mRNAs with short poly(A) tails such as such as act1, hcn1 and urg1 mRNAs, hence facilitating global mRNA decay. Uridylates the 3' ends of actin mRNAs upon S-phase arrest. Also has a weak poly(A) polymerase (PAP) activity. Residue His-336 is responsible for the specificity for UTP. Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis.
Subcellular Localization:
Cytoplasm.
Sequence:
MNISSAQFIPGVHTVEEIEAEIHKNLHISKSCSYQKVPNSHKEFTKFCYEVYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFGSLESGLALKNSDMDLCVLMDSRVQSDTIALQFYEELIAEGFEGKFLQRARIPIIKLTSDTKNGFGASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKHWAKRKQINSPYFGTLSSYGYVLMVLYYLIHVIKPPVFPNLLLSPLKQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAYKFEPREKVVTFRRPDGYLTKQEKGWTSATEHTGSADQIIKDRYILAIEDPFEISHNVGRTVSSSGLYRIRGEFMAASRLLNSRSYPIPYDSLFEEAPIPPRRQKKTDEQSNKKLLNETDGDNSE
The following text describes a protein:
Function:
Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA. Plays a role in the synthesis of feruloylated polysaccharides. Involved in the reinforcement of the plant cell wall. Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers.
Sequence:
MAPGLEEKQNQEGGHTNITQSLAIYKASIYYIFSNIPFLALSNYIGCFSFSLTSCTSFISCRIYLKLRSLNQHKSKKTKLVDIKKLDTRVFYRYILQTSVYPGEPEPMKELRELTATHKWNIMTTSADEGQFLSMLLKLINAKNTMEIGVYTGYSLLATALALPEDGKILAMDINRENYELGLPVIKKAGVAHKIDFREGPALPVLDQLIQDGKHHGTFDFIFVDADKDNYLNYHKRTIELVKVGGVIGYDNTLWNGSVAAPPDAPMRKYVRFYRDYVMEFNKAIAADPRVEICQLPIGDGITLCRRIS
The following text describes a protein:
Function:
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.
Subcellular Localization:
Mitochondrion matrix, mitochondrion nucleoid.
Sequence:
MAFLRSMWGVLSALGRSGAELCTGCGSRLRSPFSFVYLPRWFSSVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRTIKKQRKYGAEEC
The following text describes a protein:
Function:
Plays an essential role in viral replication as a component of the DNA polymerase processivity factor. Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Sequence:
MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDFSNIRAKLESPVTTIVGYHPAARDRQFEKDRSFEIINVLLELDNKVPINWAQGFIY
The following text describes a protein:
Function:
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
YITAPKVKAHSRVVRGLYKRILRLHEGFPLDLKVIGDQYVKSEFKLHKDSPPEFVPEFLQQWNEYADSLDSQIKHSGTQTQSLGKNLDSKTLDNLSDDQAVQLFELMKETNKENRQFNIKE
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MQRAGSCSDVGAEEEPALAAAARGEEMAGPASTAAPHTIFYGRVVVFEDFPAEKAAEVIRLAAGGAERAAVPAPASAPATRDDLPIARKASLQQFLAKRKDRLVERVPYTRPSPAEEAEKTKQPAASSWLGLGGSTMNAERLTIALLFEEFACCGSISTDLDDGEHHSSTRTGRELGLLRVRVRRRRLRLLPLLRGAATDGDGGEQAGRRCWRRACESESKPER
The following text describes a protein:
Function:
Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchor proteins (GPI-AP). Has phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI. Required for the shedding of the GPI-AP CRIPTO, but not CFC1, at the cell surface. Shedding of CRIPTO modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Also indirectly involved in the translocation of RAC1 from the cytosol to the plasma membrane by maintaining the steady state amount of CAV1-enriched plasma membrane subdomains, stabilizing RAC1 at the plasma membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Sequence:
MGRVGAGGTAREAATGSLLLLLLLLARPPPAAASNSKESEAGLVSEHFSQAPQKLSFYSWYGSTRLFHFRVPPDTVLLRWLLHVSQGSPSCTDEEITVHFRYGAPPVINPLGTSFPDNTLSHASFHIRALLSTLMLDNTSVNISHPAPGDWFLVAHLPPSSQKIQVKGFVPTCAYIFQPDMLVMRVVEVSTLEPDVPLPQTLLSYPSYLKIFVPEYTQELRLELQGCVSSVSPGCPVRVTVGATTLPRNFQRVLTCTGLAPSCHLLLSSPPWGRWLQVTFESLAEPHVTVGFTAKAVFTVCRPWSVTIHHLIQNNPNQTYDTSAIQLSQSAVHRDLGRSSRVDSGPFCLLNYPVLREDTDVVSVHFQPLNGAFVLVHSSMPSVMQLRLDTGMDSGGSFIIVLRTNKTEVTNGTLVAACVNAASPFLSFNTSLNCTTAFFQGYPMFLRASSHMANLIMPFPETDNWYLSLQLVCPESPEDCEQAVVRVETILYLVPCLNDCGPYGQCLLLRRYGYVYAGCSCKAGWRGWSCTDNSTAQTVAQQRAAALLLTLSNLMFLAPIAISLHRSFLVEASVYFYTMFFSTFYHACDQPGEAVLCILSYDTLQYCDFLGSGASTWVTILCMARLKTILKQVLLVLGTLVIAMSLQMDRRGIWNLMGPCVFAFVIMASMWIYRCGHRGQCYPTSWQRWVFYLLPGISMASVGIAMYTSMMTSDNYYYTHSIWHILLAGSAAFLLPPREEKAGSWACLQKFPCHYQICRNDRDELYTVT
The following text describes a protein:
Function:
Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
Subcellular Localization:
Cytoplasm.
Sequence:
MKIVCSQAVLNQNLSLVGRAVPSRPTHPILANILLEADGRSGTVTLTGFDLDLGIDTRFAAEQVEGSGRTTLPARVLSDIISRLPNESLTMEVSEDNAISLVCGSSQYQVQGASAEEFPKLPELPDSAAHVLPVSEFLEGVQRSLFAASTDESKQILNGVSVKALKEGMEFVATDAHRLSFYRTDFTLPEAGTQAIAAVLPVRSVRELEKILGAQAGDSVEVRFDEKQMIFQFPNQTLTTRLLGGRYPDYQQLLPKQFQQTADMERKRLIGCLERIAVLADQKNHIVKLDFAPSEHLMTVSVDAPDVGRGRESVPVQYSGQDFSVAFNVRYLLEGLKAMDATDVSFCLNGASDPAVLKPVGDGNYQYLIMPVSIRG