lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MKLIYVTFIRFVFFIYVHGKLNIDIFEKLVNIDIEYINVYKNDIEKKYMKKPNSLIYEHVSKYINLKNNYVEIVIKGKLKNVQDTLVENFLFLLPYHEAYQGTNLYALDDEGNVLKHNILKDTKDIEEMNIDPFNDDVDLSHFNLRVYEIILSRKLKLEENVLVKLSYTLGQPYFPYPLEIDFINKQNVLFYLSSKILLPYQVEKYERIEINLCEACDIVSLDDACFLKGLKKINDKNYIIEYEHNIESFNLGNKILLYFVCDYNLGYFEKVIKNINISSLGYIYEKEEYFLKNNAAKINKFDRYILSDYESRYTSPGGSNTGEAINGSDNIGFINMENKNDTVNNIPIKNNSKSHFPRNKTDKHNSIIYSLESKIDYNIYDYNYFDDLGKIYLIRGEEIYDDEKKKNILKFDVKPRYPLLGGWKFHFFNTFYHFSNLYKIKNKRNVYAYKVDISPTIKSFYIKQLIINICLPSYSYDVLINNDNLKNYVHVQTTKKKEWIDFFSERNVVTLQIYKFFPSSDEKYMNNFLVMYNLPITHIFIKPLMLIIITFFIIILSFVMKYISFNFNTISENQIEKEKIDQQLFYEKSKELYENLSFISDKLIQSINSFKGEKKEKENSEILTKLEEKWTYDFIIYTKEFYRLFEYSDKKYELQDYVDKCFNYHAVIKKFFQAQIIHNLNVNLNEIAKAEKDLLLLLKYN
The following text describes a protein:
Function:
GPI-anchored cell wall protein involved in stabilizing the cell wall. Not implicated in virulence, heme uptake, and biofilm formation.
Subcellular Localization:
Secreted, cell wall. Cell membrane; Lipid-anchor, GPI-anchor. Note=Found anchored in the cell membrane as well as a covalently-linked GPI-modified cell wall protein (GPI-CWP).
Domain:
The CFEM domain is involved in heme-binding and contains 8 cysteines and is found in proteins from several pathogenic fungi, including both human and plant pathogens (By similarity). The CFEM domain adopts a novel helical-basket fold that consists of six alpha-helices, and is uniquely stabilized by four disulfide bonds formed by its 8 signature cysteines (By similarity).
Sequence:
MKFFSVSLALAACLSMAAAQGLDGLPDCAKSCATNSIPASCGLDVKCICTDSSFISGISCCVLQSCGPDQQQEDAHPFFPTAAVEFANRICKTAGVTNMPQSPSCANTTQSATGTASKSSTATSGSSTESNASQTAATATTSTTPPTSPTSPTSTTGSTTSSAASTTNTTTGAAVTQHKDIGLIALAGAALAAFGLLA
The following text describes a protein:
Function:
Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. Detected at the plus end of growing microtubules (By similarity).
Domain:
The N-terminus forms a two-stranded coiled coil.
Sequence:
MEDVNSDVNADQEVRKLQELVKMLEKQNEQLRSRSGAVQGAGSFGPGSPVRAGASTPSSGTASPRGFPLGLSAKSGSGAGSGPRRTSSEELRDATSLLAAGEGGLLDEVEPLRPEELERLSGWEEEEESWLYSSPKKKLTPMQKSVSPLVWCRQVLDYPSPDVECAKKSLIHKLDQTMSALKRQNLYNNPFNSVSYTSPYSPNASSPYSSGFNSPSSTPVRPPIVKQLILPGNSGNLKSSSDRNPPLSPQSSIDSELSASELDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAATASRRSSGSSCNSTRRGTFSDQELDAQSLDDEDDNMHHAVYPAVNRFSPSPRNSPRPSPKQSPRNSPRSRSPARGIEYSRVSPQPMISRLQQPRLSLQGHPTDLQTTNVKNEEKLRRSLPNLSRTSNTQVDSVKSSRSDSNFQVPNGGIPRMQPQASAIPSPGKFRSPAAPSPLALRQPVKAFSNHGSGSPGSQETTQLMQTTSSPGPPMVQNTVPANPPSNINSTTLTRPAGTTVMRSGLPRPSAPSAGGIPVPRSKLAQPVRRSLPAPKTYGSMKDDSWKDGCY
The following text describes a protein:
Function:
Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates mainly with siRNAs of 21 nucleotide in length and preferentially recruits small RNAs with a 5' terminal adenosine. Probably involved in antiviral RNA silencing. Associates with siRNA derived from cucumber mosaic virus (CMV). Targeted by turnip yellows virus (TuYV) protein P0 (via F-box-like domain) for probable proteasome degradation and thereby inactivating AGO2 function in RNA silencing. Required to direct NERD-dependent DNA methylation and silencing.
Sequence:
MERGGYRGGRGDGRGRGGRGYGGGGGGGEQGRDRGYGGGEQGRGRGSERGGGNRGQGRGEQQDFRSQSQRGPPPGHGGRGTTQFQQPRPQVAPQPSQAPASYAGSVGGVAGRGAWGRKPQVPSDSASPSTSTTVVSEPVRVAEVMNLKPSVQVATSDRKEPMKRPDRGGVVAVRRVNLYVNHYKVNFNPESVIRHYDVEIKGEIPTKKVSRFELAMVRDKVFTDNPDEFPLAMTAYDGQKNIFSAVELPTGSYKVEYPKTEEMRGRSYTFTIKQVNVLKLGDLKEYMTGRSSFNPRDVLQGMDVVMKEHPSKCMITVGKSFFTRETEPDEDFRFGVIAAKGYRHTLKPTAQGLSLCLDYSVLAFRKAMSVIEYLKLYFNWSDMRQFRRRDVEEELIGLKVTVNHRKNKQKLTIVGLSMQNTKDIKFDLIDQEGNEPPRKTSIVEYFRIKYGRHIVHKDIPCLDLGKNGRQNFVPMEFCDLVEGQIYPKDNLDKDSALWLKKLSLVNPQQRQRNIDKMIKARNGPSGGEIIGNFGLKVDTNMTPVEGRVLKAPSLKLAERGRVVREEPNPRQNNQWNLMKKGVTRGSIVKHWAVLDFTASERFNKMPNDFVDNLIDRCWRLGMQMEAPIVYKTSRMETLSNGNAIEELLRSVIDEASRKHGGARPTLVLCAMSRKDDGYKTLKWIAETKLGLVTQCFLTGPATKGGDQYRANLALKMNAKVGGSNVELMDTFSFFKKEDEVMFIGADVNHPAARDKMSPSIVAVVGTLNWPEANRYAARVIAQPHRKEEIQGFGDACLELVKAHVQATGKRPNKIVIFRDGVSDAQFDMVLNVELLDVKLTFEKNGYNPKITVIVAQKRHQTRFFPATNNDGSDKGNVPSGTVVDTKVIHPYEYDFYLCSHHGGIGTSKPTHYYTLWDELGFTSDQVQKLIFEMCFTFTRCTKPVSLVPPVYYADMVAFRGRMYHEASSREKNFKQPRGASTSAASLASSLSSLTIEDKAIFKLHAELENVMFFV
The following text describes a protein:
Function:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MTLSVLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCIDGNPVLLSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGIIQNEAEYLRVVLLCALKLYVNDHYPKGNCNMLRKTVKSKEYLIACIEDHNYETGECWNGLWKSKWIFQVNPFLTQVTGRIFVQAHFFRCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENKFQAAVLEELQELSNEALRKILRRDLPVTRTLIDWHRILSDLNLVMYPKLGYVIYSRSVLCNWII
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.
Subcellular Localization:
Nucleus.
Sequence:
MNADLKRVRENTLDDSPSPSAKRRLNSNASSPIQPSDDEGMAEWMKIVEVKRKEAIYRQMLEYRRISEHETKRANDLEAQRRVLEASFHAVELCWTQIVAAVRDLAGAENLQLKEEEVLEPLLDPSTPVPELEKALRSRLPTTRQLVTRFVDLVAHNATRPASEADLQARCLKLEAEASALRSNSKLLESEISALKGSRDEAQRDLQRIRKALDRERMEHGKAQEEWKEERTRGGQATPNLRANGSGHSTPNGKVEADKKFYSGAGPSMAGVLQDTSELEQLAASRLKQLEQLRFEQTQLQQEVDRLKILANHPSEAALRESPFFQVYLHQLSTSINRAESLQTRFTATESKLDQLRDSNGEFREAVLAEARGQTETLRAQMAKKDSDIARLRGQRDELNSEIMERRAKEVEKCKYTEQIENLANSRQERISFLTSEVRRLKGKLAAAHSSDGYLSFLKESGIDGDYVKDLEAKVVTSQDQINALTSQLERVSSDTAAAKSETEVRTELESAKRLLARYERILGPNPEAAEDVRYLSQQLEKKEKERASLEMKLEEAEAATNALYSEVEGLSKLWEALDQTVKSKVLELRDGEQKITRLATEKAKADNKYFAAMRAKEAVDMEAKAAQRSVEKQLRLLERAQEVETSLRSQITANEKGLTALKNNALDLQNQLATVVAEKTQLELRLQQSQNALVEAQQIMHQRVAEAIAEKEARAKLQDEADGQMKIIKKLKERQDAVAAASQTGMSDHEWAITQERDKLLKLLKCSCCEQNFKQQVIVKCMHTFCKQCLEQRIASRQRKCPACGLAFAKEDIQTLYWQ
The following text describes a protein:
Function:
Transcriptional repressor. Binds to multiple sites in the eve stripe 3 enhancer element. Plays an essential role in the segmentation process both by refining the expression patterns of gap genes and by establishing pair-rules stripes of gene expression.
Subcellular Localization:
Nucleus.
Sequence:
MNQTCKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNISTISECKNEGKCIIDKKNRTTCKACRLRKCYNVGMSKGGSRYGRRSNWFKIHCLLQEHEQAAAAAGKAPPLAGGVSVGGAPSASSPVGSPHTPGFGDMAAHLHHHHQQQQQQQVPRHPHMPLLGYPSYLSDPSAALPFFSMMGGVPHQSPFQLPPHLLFPGYHASAAAAAASAADAAYRQEMYKHRQSVDSVESQNRFSPASQPPVVQPTSSARQSPIDVCLEEDVHSVHSHQSSASLLHPIAIRATPTTPTSSSPLSFAAKMQSLSPVSVCSIGGETTSVVPVHPPTVSAQEGPMDLSMKTSRSSVHSFNDSGSEDQEVEVAPRRKFYQLEAECLTTSSSSSSHSAAHSPNTTTAHAEVKRQKLGGAEATHFGGFAVAHNAASAMRGIFVCV
The following text describes a protein:
Function:
Part of the ABC transporter complex FepBDGC involved in ferric enterobactin uptake. Responsible for the translocation of the substrate across the membrane (Probable).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAFSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAIVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.
Sequence:
MVLYIIGLGLGDEKDVTIKGFEAIKKSSKIYLEAYTSLLGGSTSIEALEKFYEKKIIIADREMVESGCEEMLKESTENDVSFLVVGDPFGATTHTDLVIRAKELSIPVKVIHNASIMNAIGCCGLQLYSYGQTISMVFFTETTKPDSWYDRVKINRVNGMHTLCLLDIKVKEQSIENMCRGRLIYEPPRFMTVNQCIEQLLEIEEIRKEKVYDQDTLCIGLSRVGQDDQQIISGTMKELLDVDFGAPLHSFIICGDMHFIEKEYFETFRVKKN
The following text describes a protein:
Function:
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.
Subcellular Localization:
Nucleus, nucleolus. Cytoplasm. Nucleus.
Sequence:
MQKISPSESLFIQQGVENNIRSDGRNRVDYRNFAIETGEIIHANGSARVKLSQTEVLVGVKAEITHIQSEITSNLQQSDTSKRLVFSVNCCPSASPEFEGKGSEFLNIELSKQLERLYSHPNVIKNLKLTNPIISNNNNNNNKIKEAEEGKEKEKEGDIITNSGDDNCFSIVSGKYYWTLYVDAIVLDSDGNLFDALSIACRSALQNTRIPRVKAIQGEYEEITFEVSDDPEDTLSLSIDNVPICVTLTKIGNQFVIDTTLQEELCMNARLTVGVNSLANICSIQKGGIDGLDPTTINQMINTAKVVGVKILNIMDKTLKEISN
The following text describes a protein:
Function:
Histone H3-H4 chaperone that plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation.
Subcellular Localization:
Nucleus.
Sequence:
MKDLINDEEEEVEEDSDEDVGKKKRRHDDFDDNLEDEDYDLIEENLGVKVQRKKKFKRVRRIEDEESDNEDSKDSTNRDAIANELFEGSDAGSGEATMTGGGAMSVQATYMSGDLNRMEAAAPGDDVRGEGEEEEREASGSELESDPDDFIVDDDGQPITKGKKKRHIKYTDSALQEAQDIFGVDFDFDEFSKYQDEYDEEMEEEEYEDEEEEGEARPRPKKTARKRPTKKSIFEVYEPVELERGHFTDRDNEIRATDIPERFQLRAVPVTSAPEDEISREAEWIYKHAFGNPTVSVQTATEDGKGAPASEPGGRHQPPAGRKGVTAIAKIAEALKFMRNQLFEVRAQSSCSLYVAVSRFLFYCLDHSVRRFPTAEEALKGARYMVAVQISMDPLVRRCIRETFFERAKICVTPSKKGLKEIDENHPCYPIKYLKNKPVRDLEGEQFLHMSQAEGEGLLKTSIVMDSDSRSHPGSYLDEIKQLYYRDEFSNNVQEWNNQRCEALSYALSKLLYPAFEKELKVQLLLEAQDGIVKACCRKLYNWLKVAPYQVDPQMEEDEDFDTRDGIRVFAIAYENDWEVPAFGALIDGTGEVMEHLRLPHLLKRKNSWKEKERELKEHDMRVLRKFILNKKPHVICVGAQSREALQIVEDIKAVVTDLAENEQMPLINVELLDNDLAIVYMNSKKAESDFRDYPLLLRQAISLARRMQDPLVEFSQLCTPDEEIFCLKYHPLQDSVPRTDFTNGLNLEFVNRTNEVGVDINLAIAHTHTSYLVQFLCGLGPRKGYALLKTLKQSHQRLESRTQLVTVCHMGPKVFINCAGFIKIDTTSFENSTNAYVEVLDGSRVHPEAYEWARKMAVDALEYDDVTEDVNPAEALEEILENPEKLRPMFLRAGKMVTCQVVGIARRKPHGQQLDQANPIRNDETGLWQCPFCLKNDFPELSEVWNHFDAGSCPGQSMGVRVRLDNGVNGFIHIRFISDKKVTNPEERVRPGMILHCRIIKIDIERFAVDLTCRSSDLADVNNEWSVTLSQSSTNEEPNINSALTQSLRFGAYVKRVIVHPSFHNISYKEAEKLLSTMDQGDVIIRPSSKGVDHLTVTWKVHEGILQHIDVKEQGKENAFSLGSSLLINNEEFEDLDEIIARHVQPMAGYARDLTSFRYFREAEGGKREVLEKLLAEEKKRNPSKIHYVVSSCREFPGKFLLSYLPRVKARHEYITVTPDGYRYRQQMFHSVGSLFRWFKEHFRDPVPGTPGSATNARTPMGQSSYIGATPSINISNVDPQAIQRAAANIPSHMFASLSQVAGQTPSFTTPYGGTYANAYPYHQPYTPSQAVATPMVTPSYHAVATPSQAVTPRYPQTPQTSWGTQHPTTPRGAHTPRHTPSAIPVMQANPIPTVVSSGPNPMVESTPQGDATPLIDEQ
The following text describes a protein:
Function:
Has exonuclease activity on both single-stranded and duplex templates bearing overhangs, but not blunt ended duplex DNA, and cleaves in a 3'-5' direction. Essential for the formation of DNA replication focal centers. Has an important role in maintaining genome stability.
Subcellular Localization:
Nucleus.
Sequence:
ACFFEVFSDSKLPLLQYRGMMSYSTHKDECNFICDQLISSDNKPVMGFDMEWRVAFASGGGSRKTSLIQLCSSESTCYLFQLSSMALLLKKPSQLNYTILEDETIVKVGVGINSDVDKISREYDVYPRGIVDLSALANTKLKSHENWSLSGLTMHLFKQQLNKDPAIRCSNCEAIPLTREQQLYAAMDAYVSTYITGVDGKQKL
The following text describes a protein:
Function:
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of genome stability.
Subcellular Localization:
Nucleus.
Sequence:
MVVLRPKITLTSVRGRIQVTAEDGERVGPWGGTECFLSRQTGQGPCLVVRSSRHKRHQGTFFRLEGVRQVLSLYAMEGKLTVVVPHQKRLCSVFIETFADVDALQMMAATLQDRSRWKDIEKNVACRVQRITRTNVVDTKRITNMDGGTDTHLDYKQFEWGGGEDDSCAVGGVSCNPLEGARGERNGDGVESILQERPTGLPSAHSGGKLPKHMGGDELNPQLEGSTTPGRMQWTTDQIVATRLVCTGSNVFITGSAGTGKTEWLLHLVRNVLPRDDRTVVTASTGMSARLLGGCTIHSFAGIGRGEGGFNRVYNRVKSKPEVVRAWRQCQTLIIDEIGNISPDTFSMIDEIARSLRGAPEKPFGGIQVILLGDFLQLPPVDSPKARNEWTNGNDTDTDSNPIPGKLKWCFETATWESLKLALVGFRKSYRQMNDPDFALCLEDIRFGRYTRRVERILNECSTRQIKERHGIEPTLIVARRDEATEYNAERLKMLEDVHFHRYESEDYAAIPGMNLEKEVSLQQLLELRIGAQVVLLASLPDAPHLSNGDQGVVVSFAEQTRGPALPVVCFATSGGEEVLVPRVSMEVLGPEGRVIATRTQIPLQLSWAITVHRAQGMTLPLVSVRLNKCFFDCGQAYVALSRVRSREDLMLTAFDPSAIFADARAVAFYEKNFPAQRQSVEDTECELVPIKGKTRAKHPRSQGEKNSVDEGGNAPEEHPLRTDAAFTAYHDLDSQVSTDMPLVPQPPRKKRMLVEELPQVTSSAIPNFTQESNNGDANSQLQHPFSQNNLMVDDD
The following text describes a protein:
Function:
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity).
Sequence:
MLSAAVLGQPTRDNALWVTADSGKGQTRLLLDCGGHTLDTLPLHEVQATDHLLFSHLHMDHIAGFDDFFRVNFDRQSRENHLWGPPGAARILAHRLQGYWWNHAPQLRATWRIHEVDDAAVHTWRFELHEAFEIAHDEGRTPRTGPLIETPHLRVDAVPLQHQGPCLGYVLREPGRVNVDPAGLTRLDLTPGPWLAALKAGAEEVEIAGERRPAAPLRAELLREEAGDSLAYLTDFLLDEAELARLAPLLAGVRTLYLEAQYAPADADLAARNHHTTTEQGATLAARAGAQELVLLHLSRRYREADWREMLRAAQAIFPAARFAESWLRGT
The following text describes a protein:
Function:
DNA-dependent ATPase and 5'-3' DNA helicase. Unwinds D-loops, R-loops, forked DNA and G-quadruplex DNA.
Sequence:
MLSAELKSQIQGAYTRFLEAKELKPRYGQRLMIAEVAKALGVIKEDEEGHREGEPAVVAVEAGTGTGKTVAYSLAAIACAKASGKRLVIATATVALQEQIVHKDLPDLLRNSGLAFSFALAKGRGRYLCLSKLDVLLQEGQAQSATAQLFADDGFNIDVDETSSKLFNQMIERLAGNRWDGDRDSWPEAIDDAHWAQLTTDHSQCTNRHCPNFQQCAFYKAREGMTKVDVIVTNHDLVLADLALGGGAILPDPRETLYVFDEGHHLPDKAIGHFAHFTRLRATADWLEQIAKNLTKLLAQHPLPGDLGRLIEQVPELAREIKTQQQFMFTACEEIGDFRAGEDMEGRERPRHRFVGGVVPEHIREMGIELKKGFSKLTDLFTRLTDILKEAMDGEGAGGIASHQAEEWYPLFGSLLARAQGNWELWTAFTCEDPQDSPPMARWLTLAESGSFYDIEANASPILAAETLRRNLWNVAYGVLVTSATLTALGTFDRYRMRAGLPRNAVTAVVPSPFHHAEAGVLRVPDLKADPRNAAEHTAAIIRELPELVKGARGSLVLFSSRKQMQEVFDGLDRDWRKRVFIQGNLSKQETLNKHKSRVDDGEDSVLFGLASFAEGVDLPGAYCEHVVIAKIPFAVPDDPVEAALAEWIEARGGNPFMEIAVPDASLRLVQACGRLLRTEQDRGTITLLDRRVVTQRYGKAILNALPPFRREIA
The following text describes a protein:
Function:
Probably involved in membrane trafficking.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein.
Sequence:
MAYGGWGAVGGGAWGGGPGKPEEDEPEVPRQAPTSNNVAFGANAYSPPPQSSSQPDLATTSQRSQAPAAGGNTAFGSSAGAYGQAAAAPPSPYGGGASTSFGASSTADPALKRKEAELAAKEKQLKELEAKLTAAGATIVKKNWPICYPILYHDIAEEIPAKGRRVVREGYMAWYGLCICLLWNWFCTCVMLGTNANQKVPSWFLGLLYMLLGIPLSWWLWYKRLYGAAKADSAFGFVWFFVWFAVHTAFCIWAAIAVPFSANQWSFAGFVTAMNALDKGNFPGIVYLVGAGCWSCEAAWSCWVIMDVFLFFRGKGGVKEAKEEAKKEAAMSVLRGQMASQV
The following text describes a protein:
Function:
By hydrolysis of the attached glycolipid, releases soluble variant surface glycoprotein containing phosphoinositol from the cell wall of T.brucei after cell lysis. It also cleaves similar membrane anchors on some mammalian proteins. VSG lipase may play a role in processes such as parasite differentiation or antigenic variation.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MFGGVKWSPQSWMSDTRSSIEKKCIGQVYMVGAHNAGTHGIQMFSPFGLDAPEKLRSLPPYVTFLLRFLTVGVSSRWGRCQNLSIRQLLDHGVRYLDLRMNISPDQENKIYTTHFHISVPLQEVLKDVKDFLTTPASANEFVILDFLHFYGFNESHTMKRFVEELQALEEFYIPTTVSLTTPLCNLWQSTRRIFLVVRPYVEYPYARLRSVALKSIWVNQMELNDLLDRLEELMTRDLEDVSIGGVPSKMYVTQAIGTPRNNDFAVAACCGACPGSHPDLYSAAKHKNPHLLKWFYDLNVNGVMRGERVTIRRGNNTHGNILLLDFVQEGTCTVKGVDKPMNAVALCVHLNTNQTARS
The following text describes a protein:
Function:
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
Subcellular Localization:
Lysosome.
Sequence:
GALTDSLWCLSLHTNRTFQIDYERDQFLKDGKPFRYISGSIHYSRIPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPLPGVYRFSDDYDLEYFLQLAHEIGLLVILRPGPYICAEWDMGGLPAWLLTKKSIVLRSSDPDYLAETEKWLGVLLPKMKPYLYQNGGPIITVQVENEYGSYFTCDYNYLRFLQQLFHKHLGEEVVLFTTDGASEDYLKCGTLQGLYATVDFGTNHNITEAFQSQRKTEPKGPLVNSEFYTGWLDHWGEAHETVDTKAIISSLNDMLSQGANVNMYMFIGGTNFGFWNGANIPYAAQPTSYDYDAPLSEAGDLTEKYFALRELIGKFEKLPEGLIPPTTPKFAYGKVAMKKVNTLEESLDVLCPEGPINSTYPLTFIEVKQYFGFVLYRTTLPKNCSEPVPLSSPLNGVHDRAYVSVNGVPQGVLERNKVISINITGKAGDILDVLVENLGRINYGHDINDFKGLISNLTLGSVMLKDWSMFPLNLDAAVQNNLESHETWSNNPSSPSLPTFYVGQFSIPTGIPDLPQDTFIQFPNWNKGQVWINGFNLGRYWPARGPQVTLYVPRHILVTSSPNNITVLELEKSPCEDPRKCFVEMVDTPVLNVLPSSKKS
The following text describes a protein:
Function:
Component of the DSC E3 ubiquitin ligase complex which is required for the sre1 transcriptional activator proteolytic cleavage to release the soluble transcription factor from the membrane in low oxygen or sterol conditions. The complex also plays an important role in the multivesicular body (MVB) pathway and functions in a post-endoplasmic reticulum pathway for protein degradation.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MSSANIVPSNMGITKFLLLTISTSSVVAGVFALKPFFHINFGLHLLSHYQYWRILLWQFIYWNSTEVFQALFIIYQARDVERLLGSHRFASFCVYMFILGMFVTPIFSFLYSLLFKNLDYIQPGPTFLIFAILYQYYYIVPSTVFVRLFNIKFTDKFQMVIPMIGLAFSHFPSTFINAFLGWTMGMFYHLSLLPGTSWRLPIRFVKPALSPTHVFIRPPYSDMQNASTFNPETLFALPTGLDAERTENENQVENPVSNADANDSPTRQNARATAIASSSNTAASFRNRQQISHPPLGRTSSSSVLPTGPASQLYDMLSGRSERPELGNIREEDINTVQTIMQTSRAQAIQALSQTNDVQRAVELLLEQTADY
The following text describes a protein:
Function:
Inorganic pyrophosphate (PPi)-dependent phosphoenolpyruvate carboxykinase, which regulates the carbon flow of the central metabolism by fixing CO(2) to phosphoenolpyruvate to produce oxaloacetate. Can also produce pyruvate and diphosphate from phosphoenolpyruvate and phosphate.
Sequence:
MSVVERRQINAAINLRLSLLGLPHPDSNAESPDAILVEPLLARQRELSRRLKDRLSAPDLRIQRFLDDYLADCDEHPQLPRTTLVLDEPGLARGLSLPVDGDEFHSDIVASYRLVNGVLHNPKHDRRTTAGVFHISTGGLPIPQDKVEVDKNVYARILARAFQAPDEELALPYTANLPEQAHCWASLLMRPTVLPAVPGRTTEKSYEVHFIVPGGLMCNLDFVEGIFGNAGDPYLPENDASLDPDSWTGHTGCVILAPHLTTMTKKSLGMPHYDDATERQRRDGQCWRHEDDLYNDGKAFKVCARDERGVIVTVIADNYFGYCKKEVKTQISYSANLLGGAEEEHSGGAEVYPAWNLNQDFTDRTPDDFTLADVISTNRELLDVRPEGYAVYKPEPNIVFIPEHSHYSMRTQTISWTAHGAEQTIKLLAGKHYLSPDGYRIHAKHREMDATQWHLIGTSSRAVTCHKPATVSGGGKSEISKSISDAFVFGNAFSHDIDSAMDQVQALFDTDFTNRFADASRNGTDHRPVLSIDRSLGSVIKLLTPSIQYNDEYNAFLEGIEPDVKELAFTVKRYYLPEWGEDWRSHFTVGIMNGRHGNMVRLDGKKIITNMLRVGFREDGSWRLFTLRPDYSPAVKVQTEDDITASTVTPPWEDAEGLPRKYVTNCEHLLFQRPDDAIHRGYDKQAEFDLASGTDTFISNFEPLTHEQARDLLTDVQAYSEFTKPVRKLIERVAAMPDDQSPEFWVCSDDPRHLPDGGRSKNPRYLQVRPTDSNPELTTVADVAGKLARKLPLAGHAPQPIDVVAAGRRNNPPEDKVPALCAYNPLHYMELPELFMEYISSMTGKSPSTTGAGSEGALTKGPFNALPAVYDLNAALLSYALTDYDGWLSSAGYIGPNARVDHDISMLIPELFSHMGPNDRNTKRLISEGYLEKMQDFDFDGHRVLASRLGYRINDRFVTHYFGRIFLHPDVVFSEEMLRPELQDEKIFADSIDVIVKTHQRVAQMYFDDGTVSLACPPIRALLEIMAHGASAEGWTLDSPEFRKLFERESVLASDWYAQRLDAKQAEDVKQAEEGVERLKEYIGRSDSGSVTGRLHLADRLRELEAQLTYERSPEYRQSLVGTLGRQPRFV
The following text describes a protein:
Function:
Small heat shock protein required for the establishment of auxin gradients and for patterning of the apical domain of the embryo. Involved in the specification of the cotyledon primordia. Also required for normal inflorescence and floral meristem function, normal developmental patterning and thermotolerance. Acts as a molecular chaperone.
Subcellular Localization:
Cytoplasmic granule.
Sequence:
MAILSDYQEDQPHDQHYSSNSFSFNAVLDPSNPLGFLESAFNFVSQKSDLFKNDSAEKEIMSSVRSIKEKIKAQEADQKKRLKLAEASAKMATDQKEQEQKEKEKEKKQLVPNHGNGLDMENYSWGQSLQEVTINVPVPHGTKSSLVLCEIKNNSLKIGLKGQPPIIDGGLYKPVKADDCFWSLEDQKSISVLMSKRDQIDWWKSLLKSGPEIDTQKVEPEPSRLSELDSETRSAVEKMMFDQRQKQLGRPSSDEIQKQELLKQFMAQNPNMNFSGTKFR
The following text describes a protein:
Function:
Probable helicase-like transcription factor involved in transcriptional gene silencing. Associates with SUVR2 and contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci. May be involved in nucleosome positioning to form ordered nucleosome arrays on chromatin. Associates with SUVR2 and functions redundantly with FRG2. Required for the efficient methylation of a broad range of RdDM target loci.
Subcellular Localization:
Nucleus.
Sequence:
MDSAIEISSGSDSDDEVPPQPVWPQTRTRMDPTWLSRRPLPTVDSHARAEHTNQAPPNGASSDTSRPGVSKPFTGNGNTVNSRISSGSGADYVRLSSEQALKRTLPPSFNSPPLPARSGTNNISNASGSRVGVDYERPLSQQALKRTLPPSFNPPPLPSRSGTNNIRNAGGSRFGADYSHPAVSAVGNKSTFGDHYSGAHAEIGIQRGVNGVRILPPSLTHGTSASVLHHAGSSDPMHRFGGGEDRNPDNDERLVYQAALQVLNQPMTESDLPPGTLSVPLMRHQKIALAWMFQKETSSFNCPGGILADDQGLGKTVSTIALILKQKIVSQLKSESSCKQETEALVLDADDESDNAKHESGSHVKPELKVSSNSETSVLSACGNDENDSSDMEKAEDEEANSSTRAFQWKRPAAGTLIVCPASVVRQWARELDEKVSEESKLSVLVYHGSNRTKDPNELAEYDVVVTTYAIVTNEAPNKFLVDEDENDEKNTDRYGLASGFSNNKKRKVVVGASKKSKRRGRKSTNDTSSEPDCGPLGKVGWFRIVLDEAQTIKNYRTQMARSCCTLRAKRRWCLSGTPIQNTIDDLYSYFRFLRYDPYAVYKSFYSTIKVPISRNSCQGYKKLQAVLRAIMLRRTKGTLLDGKPIINLPPKVVNLSQVDFSVAERSFYKKLEADSRSQFKAYADAGTLSQNYANILLLLLRLRQACDHPQLVKRYNSDPVGKVSEAAVRRLPREARSRLINRLESSSAICYECNEPPEKPVVTLCGHIFCYECVLEYITGDENTCPVPRCKQQLARDVVFSESSLRNCTSDDSGCSSSHDNGLDRSVFQKRDFCSSKIKAVLDILQSLSQPDSPNSAQHGQMPSSSRPYDDDDVTIVEPMRLHSSSPSQGAVKTIIFSQWTGMLDLVELRILESGIEFRRLDGTMSLAARDRAVKEFSKKPDVKVMLMSLKAGNLGLNMVAACHVILLDLWWNPTTEDQAIDRAHRIGQTRPVTVTRITIKDTVEDRILKLQEEKRTMVASAFGEEHGGSSATRLTVDDLKYLFMV
The following text describes a protein:
Function:
Ubiquitin-like modifier involved in autophagosomes formation. May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane.
Sequence:
MAISSFKQEHPLEKRQAEASRIRDKYPDRIPVIVERAEKSDVPDIDKKKYLVPADLTVGQFVYVVRKRIKLSPEKAIFIFVKNILPPTAAIMSAIYDEHKDEDGFLYMSYSGENTFGIF
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MTSPVRSRAQVFPERQEPAVHSSADWRRGVPEHHNMEQNLCNPSAMNSDRNPATERIMSLILEIIWLLTGEDCVVVKKQDGQSVPSSSSADVSEGFLMVQGSKTDPTPRSQTPESNSSRKSLQPLPCEVPEREEDVAIRVTIEEREYGERHKKRHKGKAKPHKDRPPLNEFSDVSERSHLPAYTQEGLEENRLISPNYQMEPRVGMLPQQYKNDESIRNQMSAEPFPTQTAADRCPIPPYSRHCAHESGGILEIHQGYKEEAEETPTEMNSDEAISRNTAGTDHSPPYSQDFIHEENTSTQDFQMEQLDVIVLQQCKEEEIPAEISTGNPTTWEAQLDACPILPSEADFGNRSFVMDTSINGDGRKAGTVPESHPVLPTTKDLTGYNYNCRVCGRIFASELDFRSHQILHTNKKMYSCFGYEAREGLAAQQIAQNDKRTESLLYNSADTEQQQQMHAKKKSYMCLICGKCLSQKSDLIIHQRIHTEEKAFACTHCGKCFRHKSTLVIHQRIHTGEKPFVCCDCGKSFKQSGHHLAHRRIHTGERPFACTECGKSFKRKSTLHSHQRTHRRK
The following text describes a protein:
Function:
Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.
Subcellular Localization:
Nucleus.
Sequence:
MAKRKSMSSKMAQRKKPAPKLETSFCCPFCNHPDSVACTIDLKLLVATAVCYVCEEAYHTTAHYLTEPVDVYYHDWIDACEKANQDDECFKRQRRVSSDDDDSDA
The following text describes a protein:
Function:
Probable serine/threonine-protein kinase.
Sequence:
MEESGQLSDFKLPEGIKDPSLEFDLIECLGRGSFGSVYKATYKKTGNIVAVKLVPINEDFQEILKEINIMKQCKSKYVVQYYGNYFKDETCWIIMEYCAFGSVSDMMNITNRVLNEEQIALVCYSTLKGLYYLHRNSKIHRDIKPGNILVSEEGECKLADFGVSGQLSERTRKRNTVIGTPFFLAPEVIQEVGYDNKADIWALGISAIEMAEFHPPYHDLHPMRVLFMIPTSTSPTLKEPHKWSPEFSDFIALCLAKEQSQRPSAKDLLKHSFFEKKLKGSYVMKSLSETAQMVIERCGGREEAVKAAAERKSKQSGVSVDFIHCESVDEPDSSDEEDLLERNNKRLSTQIQQKKEQQAQQQQQQAQQQQQQQQQQQQQYQPPSPNNNNRTTTKNNDINELDSLLNNMMMSSSASASTSPSPSSISSNGNKSGTTTNDYHTGNGRTSSSSPQFGLQHQNSSNSFPSSPNTVPSVESKPRQPASELDDLLEEMMNPSFGNRARNSSGGGGGLTPIGSPITKRPTPTMQSSTTTTTSSSSLPLPMSPSVYLSPTRVSGIWSGESAGGCANTTLWRKNPQYLLQITATTTIRITLRQTGDKLVHIGFYFARSNTGANDQFRRRITLTKEYLVPGLDITFLKSTEVSAKITMEPGYYVIIPATFEPNQEGSFELDVTATSDNIGGQYNSNNNIKLSEIKGDRDWRIISDRFEWRGSSAGGSFSGSSATWKDNPKFFFETTQTSNTTIVLGKLSDIPKETYIGFYIFKADKNCPFISLTANNLYSKTSFVNGIEVVHTQQQMPPGCYIIVPCTYDSRQEGSFTLTCYSDCQQGSIYKLDLSEQILTVHGEWRGATSGGCLNHTTWRNNAQYLIHNTSSSPTKVTIMLEQLEKMDNQQLPFVGFYVAKSPTPNLDKKLFSLTPKDIVGNTEFINDYQVHFTSIMEPNTSYIIIPSTFTPGIEYPFNLRVITNQHNVIQISRLPEWSTRKLSGEWRGQSCGGRYSNTSSSWTLNPRFRFNLPRGGRFTIILAQAEKPSYNGIGFYYFKTLQDGTLREFVCKSGFICGKEIVLESSINEGVTGVVIPSTFEPNIQDSFNLTIYSEFDLDFYNN