lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May be involved in several stages of intracellular trafficking. Could play an important role in the regulation of glucose transport by insulin. May act as a downstream effector of RHOQ/TC10 in the regulation of insulin-stimulated glucose transport.
Sequence:
MEEPRPCNPSGTKESPPDTEQKARGTDTLDSANESRLLSSAANPGVKGRPSKRITRGPFVKLADCAHYHYENVNYGPIQLGLSDSRTEDAGSTEGDVIYIVQVTCQGRSWSVLRSYEDFRVLDSNLHRCIFDRRFSQLLELPPRSELPAQGQLLAPLLSRYLKGLTGIVDSNINCGPILNWMEIDNHGNRLLVNEEASINVPAIAAAHVIKRYTAQAPDELSFEVGDIVSVIDMPPREDTSWWRGKHSFQVGFFPSECVQLITDSKSPSPTGEGDVKLPITPPHGSNSPRPVCRRHGKLAGLLRSFMASRPSKQRLRQRGILRERVFGTDLGEHLLNSGEEVPRVLLCCAQFIEKFGVVDGIYRLSGVSSNIQKLRHEFDSERIPDLSRDTFLQDVHCVSSLCKLYFRELPNPLLTYRLYQPFTEAMSAATEEDKLIRVHDLIQQLPPPHYRTLEYLMKHLSQLSTHSDRTGMHARNLAIIWAPNLLRSRDMESVGTPGADAFREVRVQSVLVEFLLCNVETLFSDTFTSIGRCGPIRPRSLLGVCPSGRLVSLQEAQARSQSQREAAEKLGAEKASPTKAERGLESSEERKAARGRKKSGGGSSWRTFFAIGKNSSHKKSRPGGIGNAAAHPRVSDTVTLRSAKSEESLCSHTSGTGLQRSSRLRRPRSTSDGLTTRLPHSRSVESLGPSSPSPPCVPSPPASARPQSAWIEEELDLSPPLPDTDGLGFDPLSFRLSFSDHEEAKSPIIVRAEITSPALAKALPRGVSLSPTAGCSPSPTHSPPERLLVDGPSQGPRDLSPPPQMLSLLLQSCQQHLSDKSVREVKGKLTGAPGQEEPPNSLSPQESAQPPSLSLLRQLPPPPPPKDPARLMALRLAESAQRALQASISIGTVPAKVSQRSAPMNPPTSAFRRSLSMECSESAVPRELYSDLRPPALSTNDKSVGQHRPLRLPAHNTLAPSSSPADVRKPTPTGIPPTRAPRLHTRSGSLPAPPSLCPPRIRPPPYRFPEEGPRLPHQCSAPPWPEPEGLYYEIVGDPPHMAPLNTSYGLIQPPWPHVGSSQAHSGFGNWYGASHGTDPEVVAYSRWDRGLHPQLRPYMVGGGVHYPYVRTPESVGKREEPIYVNLPLKGREQHDGTNDVAGLKPELPQKQRPPNPPSMAYHESIRGVAQRQVRHPHLLRREGSLGYFRPPSSHKAMWGTQHKFPQGRENPIFAYEAPTGAGQRMRYVHPHCLLSEEGTLYGNLEQRGVQHRSATPVGPPGFLRAPWTVHSEGQTRSYC
The following text describes a protein:
Function:
May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis (By similarity). Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (By similarity). Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm. Note=Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane.
Domain:
The CXXC zinc finger mediates binding to CpG-DNA.
Sequence:
MSSLGGGSQDAGGSSSSSNTNSSSGSGQKAGGTDKSTAVAATTAPTSVADDAPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGGGGSMMGVESADKAAAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLPDMEAVAGAEALNGQSDFPYLGAFPINPGLFIMTPAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPSGAAFRWFQ
The following text describes a protein:
Function:
Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. SDS3 is required for the HDAC activity of the complex and for the RPD3-SIN3 association.
Miscellaneous:
MISCELLANEOUS: Present with 105 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MAIQKVSNKDLSRKDKRRFNIESKVNKIYQNFYSERDNQYKDRLTALQTDLTSLHQGDNGQYARQVRDLEEERDLELVRLRLFEEYRVSRSGIEFQEDIEKAKAEHEKLIKLCKERLYSSIEQKIKKLQEERLLMDVANVHSYAMNYSRPQYQKNTRSHTVSGWDSSSNEYGRDTANESATDTGAGNDRRTLRRRNASKDTRGNNNNQDESDFQTGNGSGSNGHGSRQGSQFPHFNNLTYKSGMNSDSDFLQGINEGTDLYAFLFGEKNPKDNANGNEKKKNRGAQRYSTKTAPPLQSLKPDEVTEDISLIRELTGQPPAPFRLRSD
The following text describes a protein:
Function:
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Sequence:
MANRPKGFGMTAELANKKAAKFDADLADETLQWIVSILNTGSSEDQQLASQIVKVKTEKDVHTPLKDGVILCHVVNIIKPGSVRKVNSSKMAFKQMENIANFLTGCEGLKMNKTDLFQTVDLYESGNIPQVVFSIIALGRKAKAMGLQGLGPKESTANKREFTDEQLRAGEGVIGLQAGSNKGASQAGQSFGKSRMILD
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MTPTPTVGEARPVQKRLYTRLPALALLFYLLCLSPTAQGNDGLVTVLQPMNSRQIERTFQTQTRVVSRSGSDADAFLTQLRETEPLAQHMASLEAFGSIYRQAAGFPNAIKAMRLNQKYSTTPSWAELQNMSDVTSVVYKREFDRKAQPSALESLIESELGIDATVHAYFTPANAQTLEPHTDPYDVVVVQVANQKHWTLCLPQTDNATVSLSEADRAQLQEIKRSHLDGCTTYTMSMLQPMICRNVTLHQGDSMYLPKGVIHYAVTTDTPSAHLTIGLSRTGRTWLDVLTAQCQRTTLPSYVCHQYEALANAVGQTPEGLIWHELAVPGLATWREQLCASLSPLIMGEASYSLLSALSGIRFEQLQRSLGDRSGLYWPRQKLRQNLGALLQCAGNELVERVSSVRDTAMGMERSRRGTSWVAPCSSAGTCSSSGCDCDGSNCGGSVNCDSSCDSGCDQNCGCDGGTSCNAGYYQSGDTVDGVCVACTAGKAQSSSGQTSCSSCAQGKYASGTGNTACTSCSSGTYTDQTGQSSCKQAGTGYYVSDSDRTTRKACPVGKYSDVNTANSCKSCQSSPWPGKYQDSTAQSSCQTCPDGTYVTTTGATECIDQPAFSVTYEAYAKNITIKIDNSAQRWAKFRVTLGLWRDREYAYDDAVGYPLEVSADTSGSGYADISDHTFANLVPGQYYYLKVESQDKDASEYEDEAAEFNIVQTTCGCDQSDTTGPPIDVSATQHMGKIFFQWTDESYCEDGFIMRRDTNTFTSSYDVASSSACGTTHHPETIYDDAVISPEVDVGSAYSYCISAYSRTTVVWADNQQLDSRYESSQTCIDFKIKWEAMVKGSVNIGNDEFESVPVADTTIEWTLGGVLSGTTTTDSNGQYEIYIQTDLLSQKYEQMNISVSKQSEAVNHTYECDGLPCTSRTFLVEWLTFNTEADFTDVSAVPVYGYVYINGTESDSNPDGCGMNNAHVCFNSHYSHSAIVCAYTDATGYYVAPIPAGMVVYGTVDRTPDGTVDTLSLVGDVLAYSYFSISFDELSSESINFHDVTTRNVTLQVAGGKCNRTLGTSTLVFSLPTCTIQKEVPVRYETTLQMPATLWEVTYTGTLPDDDTDIGDMMINYFEAAGTLTQDADLSSDDTTVRWEYHSAATISVDIGSTLASSCDVHTINRDVISNVTVYVYEEYWNDQDDCTWVEGSLSVTNLLGESTAVADNLLAQSSITDAEYSRLVVCNTGCELELLYDDGDTSDTYTNARGELEIQTGEPELSSGEKEGVKYAKIFSASFTQSVYQPSTTYIPVVVLGSKIISDRFTMDFPEYFPLTIVYDPPGGESYAYYESAEASMTITHSEYKAFAGAYSEVAGGLSFGTSMETCVLMACVQWADYKTHVGVQTHIDTLESDLKGDRNADGSAVFTTTFSLKTSDYKGTPSDHLIITPSLVVRFADVRTISFNYTTCEASSSQDVQWSLNPRSATGAFSIKTYRFLQLEEIPTLQNNLALAQASYDALIAEGSTNDALINETLAKVEKLTEAIDGWTDIVDYIDNITAQAAAGNLTAQTNLMPTNLMQQARDFDMSLSSNAQASLEKNNAISFSGGGAKYSYETADEEESSKTTGHEFQLDWSTFVHADHDFEGATGGYIEGDLGAQGQNFRLNHTTRGTQTAERQGFELSDGDMGNEFLVEVYRDPYFNTLVFHTSAGSSSCLHESNTYALEQPRVQISREPTSAVLPSSKAFFTVYLMNDAISSATYELYVRNETGVSVAADGHPLFEPLLFEQMPGLGQYEQVIAIERYDMSRYTFDVVLGFRSRCESIEFLGRDDSAYELMQFSEVTLSVEFLQPCSQVDWTGTMSRESSFLVSIEENAEVFRITLTNPETSSRRWEDNARLEGVHLMYRRVGDVDWTYARNASGDILNFMYDESDYGYSSLNWAVDGVLDGEYELQTAAECTAAGLDPPDGINEVFSSIISGRIDREAPEIFSQPEPVDGVFSAGDVISVKMTEDILCSRPFLFYLSVDIDGLLQLGTNDVDIKCSGDTLSLSLYRHFSAATLAGTSVTVTITNLLDLAQNAADEISWTYEYEATTEDSTTVSVTVSQLVLTVAWNDTYADLSSVASIALAAEVASELATSLGISSARIAVTRFSDENNMTAADLVFLPPSTTTARRRRSEDLSSEALVFLLEQALQNGGNFSIVSADGNTYLETSSVIDTDTSTTEATTVTTTTTTTTFAAASALSQTWDSDVSAVFGLVVAVLAVQVLGFVGLYLYLKKRLGSKHSDAAALGRKKGHFALASQRQPVSTSRIESRPRLQESQMSGEGTYNLATSAKTTVQLIDNDNDYDFARNPSLSGRRLSVVEA
The following text describes a protein:
Function:
Required for the use of extracellular DNA as a nutrient.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MNMFFDWWFATSPRLRQLCWAFWLLMLVTLIFLSSTHHEERDALIRLRASHHQQWAALYRLVDTAPFSEEKTLPFSPLDFQLSGAQLVSWHPSAQGGELALKTLWEAVPSAFTRLAERNVSVSRFSLSVEGDDLLFTLQLETPHEG
The following text describes a protein:
Function:
Regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm. Nuclear export is mediated by emb/Crm1 (By similarity).
Sequence:
MSTYLQSSEGKFIPATKRPDGTWRKARRVKDGYVPQEEVPLYESKGKQFVAQRQAGVPPGMCPLVAAESKKEREKQERTRAKKQEKESGRQPKAPAPGVLVMPPSTCPPPKVSQQQQQQPSGSRDINSISKAMEDTLKLDAPQEVVDPAKQLKKLRKKIREIEQIESRIQAGEQKKLDKDQLDKVKKKSEILRQIKDLESTPRS
The following text describes a protein:
Function:
Plays an essential role in the innate immune defense against viruses and bacteria. Promotes the 'Lys-48'-linked ubiquitination and subsequent degradation of hepatitis C virus NS5A leading to the inhibition of viral replication. Also plays a role in the inhibition of ebolavirus infection by enhancing IFN-beta and NF-kappa-B activation after binding to the viral protein NP. Facilitates the type I IFN response by interacting with MAVS at the outer mitochondria membrane and thereby recruiting NF-kappa-B essential modulator IKBKG/NEMO to the MAVS signalosome, leading to the activation of both the IFN regulatory factor 3/IRF3 and NF-kappa-B pathways. Positively regulates the CGAS-induced type I interferon signaling pathway by stabilizing CGAS and inhibiting its autophagic degradation. Acts as a scaffold between TBK1 and STAT3 to promote phosphorylation of STAT3 and resolve interferon-stimulated gene (ISG) expression. Inhibits the transcriptional activity of SPI1 in a dose-dependent manner (By similarity). Also inhibits OPTN-mediated selective autophagic degradation of KDM4D and thereby negatively regulates H3K9me2 and H3K9me3. Mechanistically, recruits USP14 to remove the 'Lys-63'-linked ubiquitination of KDM4D, preventing its recognition by OPTN and subsequent degradation.
Subcellular Localization:
Mitochondrion outer membrane. Cytoplasmic vesicle, phagosome. Nucleus.
Domain:
The B-box zinc finger is responsible for inhibition of SPI1-mediated transcriptional activation.
Sequence:
MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRLP
The following text describes a protein:
Function:
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular Localization:
Cytoplasm.
Sequence:
MLIPKEDRKKIHQYLFQEGVVVAKKDFNQPKHDEIDTRNLFVIKALQSLTSKGYVKTQFSWQYYYYTLTDEGVEFLRTELNIPEGILPLTRLKNAPAERPRPSRGGPRRGGYRGRARD
The following text describes a protein:
Function:
Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.
Subcellular Localization:
Nucleus.
Sequence:
MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLAQQGHYDSYKQHQPTPQPALPYNHIYSYPSPITAAAAKVPTPPGVPAIPGSVAMPRTWPSSHSVTDILGIRSITDQVSDSSPYHSPKVEEWSSLGRNNFPAAAPHAVNGLEKGALEQEAKYGQAPNGLPAVGSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVAGHGWQHAGGTSLSPHNCDIPASLAFKGMQAAREGSHSVTASAL
The following text describes a protein:
Function:
Is involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MEKSEVKLLGAWPSPFMLRVRIALHLKSINYEFIEVDLLGPKSELVLKSNPIYKKIPVLFHDGNTILESQIIVQYIDEVWPNAPSILPSDAAQRADSRFWVAYFDDKLVPALIIALAAKSKDTKNAAIAELEPGLVHLEEAASTKLSKGKALFGGENLGYMDIALGPFLVWIGITEKLNGVKLLNETNTPSLLRWADSFFSHAVVKTIFPEVEKLIEFAMMLIPVLRARPELRLLLGISD
The following text describes a protein:
Function:
Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. This reaction involves an intramolecular CoA transferase that catalyzes the reversible transfer of the CoA moiety from the C1-carboxyl group of mesaconyl-CoA to the C4-carboxyl group. It does not require free mesaconate as CoA acceptor.
Sequence:
MKGILHGLRVVEGSAFVAAPLGGMTLAQLGADVIRFDPIGGGLDYKRWPVTLDGKHSLFWAGLNKGKRSIAIDIRHPRGQELLTQLICAPGEHAGLFITNFPARGWLSYDELKRHRADLIMVNLVGRRDGGSEVDYTVNPQLGLPFMTGPVTTPDVVNHVLPAWDIVTGQMIALGLLAAERHRRLTGEGQLVKIALKDVGLAMIGHLGMIAEVMINDTDRPRQGNYLYGAFGRDFETLDGKRVMVVGLTDLQWKALGKATGLTDAFNALGARLGLNMDEEGDRFRARHEIAALLEPWFHARTLAEVRRIFEQHRVTWAPYRTVREAIAQDPDCSTDNPMFAMVEQPGIGSYLMPGSPLDFTAVPRLPVQPAPRLGEHTDEILLEVLGLSEAEVGRLHDEGIVAGPDRAA
The following text describes a protein:
Function:
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MDVFWTLPPVSRTITALAVSVSALGYGGIISLSNYVFFKPFVFTTKIVPQLWRPLTAFLITKPKFGILMDPYFCYQYGSGLERESARFTQPGDFAVYTAFCASFIIATAGGFLNSYTFLPALTQSYAYTFAQDNPTRQVNFFIINFDAKFLPFALLFMTFIVDGPDSAAAQLTGLLAAHLYDFLTRIWPTFGGGKNYIVTPNFVKRLFNAGVGSGAREWSCDWRAFCGGGGEQ
The following text describes a protein:
Function:
Involved in nucleotide excision repair (NER) of damaged DNA. Required for the repair of RNA polymerase I-transcribed rDNA and RNA polymerase II-transcribed DNA regions. May have a role in stabilizing the DNA repair proteins RAD4 and RAD34.
Miscellaneous:
MISCELLANEOUS: Present with 1080 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSKSTNVSYERVELFENPKVPIEVEDEILEKYAESSLDHDMTVNELPRFFKDLQLEPTIWKLVRNEDVIIEGTDVIDFTKLVRCTCQLLILMNNLTVIDDLWSMLIRNCGRDVDFPQVALRDHVLSVKDLQKISNLIGADQSSGTIEMISCATDGKRLFMTYLDFGCVLGKLGYLKM
The following text describes a protein:
Function:
Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Subcellular Localization:
Mitochondrion.
Sequence:
MSLPTIRLLPRHLRPLAQQYNRAITVSISAKSYHSYDRPSSSDSPFPPTESSILRASLPHIPAHGFTLNTLSLGAQEVGYVPAATNIFPKGAFSLVHYHLYTQRLALKNHTEHIAPPPETEGGEPPKGVGKRVKSLTWERLMGNKDVIHKWQEAQTLLTLPTNLPTSLRELHALSDEIWFLSGDTAVDSSWYTKRASLSTIYAATESYMTTDRSEGFRDTREFLDRRFRDSQVLGGLVGGIGQWVGFTAMAGINVLRSKGVRV
The following text describes a protein:
Function:
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate. MdtABC requires TolC for its function.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSRSAAPGATKQAQQSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLIALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNEGHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVEAQSATTPEEKATSREYAKKGARS
The following text describes a protein:
Function:
The function of the small subunit is not yet clear.
Subcellular Localization:
Nucleus.
Sequence:
MVVAMEVDSESNLLQRKQSLYHSLDESFEIGKEVYRGQQYSQIYYARLHLMRTLLYSLLPNWKPHLPVCTVLGLEEGKECIIVGTLYKHMKLKPSVLDEYSKERSAAPLVQRHNFTHPDDNLVLEDESGRVKLSGSVLLPSTYVTGMIAALHGKETSAGDFLVEDVLEAGLPQQIERPIDLGEDKYVVFVSGLSVGRSSSNPLQFQLFVDHITGHLGDVKEQNIAAQIVQVVIAGNSVEVPHGLLNGQNLGSKDQSRLFEPIKELDILLTQIAASIPLDIVPGSSDPANFALPQQPLHRCLFPGSSAYNTFRSCTNPHCFELDNIRFLGTSGQNIDDLGKYSEANSSIEFMERTLRWRHLAPTAPNTLGCYPFTDKDPFYVETCPHVYFVGNQDKFETRLIKGSEGQMVRLICIPRFADTGVAVVGIDQPFTQKMYDVRQKFAVQKTSIRLRFIERLSCIFRRFNFGKFCNCSRILCFNLQDNSLPV
The following text describes a protein:
Function:
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
Sequence:
MILQNKTFDLNPNDIAGLELVCQTLRNRILEVVSANGGHLSSSLGAVELIVGMHALFDCQKNPFIFDTSHQAYAHKLLTGRFESFSTLRQFKGLSGFTKPSESAYDYFIAGHSSTSVSIGVGVAKAFCLKQALGMPIALLGDGSISAGIFYEALNELGDRKYPMIMILNDNEMSISTPIGALSKALSQLMKGPFYQSFRSKVKKILSTLPESVNYLASRFEESFKLITPGVFFEELGINYIGPINGHDLSAIIETLKLAKELKEPVLIHAQTLKGKGYKIAEGRYEKWHGVGPFDLDTGLSKKSKSAILSPTEAYSNTLLELAKKDEKIVGVTAAMPSGTGLDKLIDAYPLRFFDVAIAEQHALTSSSAMAKEGFKPFVSIYSTFLQRAYDSIVHDACISSLPIKLAIDRAGIVGEDGETHQGLLDVSYLRSIPNMVIFAPRDNETLKNAVRFANEHDSSPCAFRYPRGSFALKEGVFEPSGFVLGQSELLKKEGEILLIGYGNGVGRAHLVQLALKEKNIECALLDLRFLKPLDPNLSAIVAPYQKLYVFSDNYKLGGVASAILEFLSEQNILKPVKSFEIIDEFIMHGNTALVEKSLGLDTESLTDAILKDLGQER
The following text describes a protein:
Function:
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
Sequence:
MVRSVWKGPFVEGSLLKKADAARASGRHDVIKIWSRRSTILPQFVGLTFGVYNGQKHVPVAVNEEMVGHKFGEFSPTRTFHGHSGDKKAKKA
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSCWTLVQPDTLVDVPSTEQLKTALESKNDVVKISAMKTILRIIINGDPLSSILMHVIRYVMPSKNKELKKLLFYYWEVCPKYNSDGTMKQEMILACNSLRNELQHPNEYIRGATLRFLCKLKEPELLEPLIPTVRQCLEHRHAYVRKNAILAVLRIYQLSSQLLPDAPSLAEDFITIEQDATCKRNAFMVLCTIAPETASLYLLENKDAMLTLPAPFQLVAIEFIRKTAINDLENKSVFFSMLMDLLQASSNSVVYEAATSLMNMTFNTQVIKIAASKLLDLAIKESDNNAKIIMLERIAELVQRDKSALEDLVPELLRLLSTDDEDVCKKTLDIIMGLLSTRNVQEVLTHLQKELVKSAMNSERGEAHRRAFTDAIHSCAILFPPMASSAIQSLLNNVSEFKNESVASVVSFVKEVMEKFPDLRSPIIRKLLLCLREDGNEKIYRGVLWMIGEYCLTLSDIGVAWKALRASLGNMPVMESVLKEGKNSVEMSTDEQHKSSSSRKILPDGTYATESAITASATSASSTSDCLVRTAIVKGDHYLASILACALTKLVMRSSTLTDDSARINSMKAEAMLIIASFIRFLQSDYVQYRIDDDTLDRMMVCIRSLHVFPEVESLKEVYLQDSRLAFSKAMAEYEQRQKDENAEAFTQQIVQADDLLQIRQITKQSKEGEIHEFESDISKAAGDDIIVDADSSKLDRVVPLTGFTDPVYVEAYVKIQQFDIILDILLVNRTSNTLQNLSLELATLGNIKLVERPPVMNLGPNAFKSVQATVKVSSIDTGVIFGSVVFDGKTALESRVVILNGISINIMDYIKPVYIPESEFRSMWTEVEWENKVDIVRNEDITVHEFLHDLMKKTNMKCLTPESSLRGDCQFLSANLYARSIFGEDALMSLSIEKTTDGKILGHVRIRSKTQGVALSLGSVVAA
The following text describes a protein:
Function:
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MPPSLLSLEGATVRFGGRAVLDDVGLGVAEHEVVCVLGPSGSGKSTLLRAVAGLQPLDAGRVTLDGRDQSGVPAHKREVGLMFQDHQLFPQRDVAGNIAFGPRMRGASRAEQQARVAELLQLVGLPGAARRSVAALSGGEQQRVALARALAPRPRLLMLDEPLGQLDRSLRERLVVELRELFGRLGTTVLAVTHDQGEAFALADRVVVMRDGRIAQSGTPLEVWQRPADAFVARFLGFENVAEASVAGQAADTPWGKVPVPEDAPQGTRTVLVRPAGVRVVPADEGLRCTVTARTFRGTHVAVHLQPEGAPRLEAACALRAAPEVGAAVGVEFDAADVVVLGGSGVPE
The following text describes a protein:
Function:
May be involved in the regulation of cell differentiation; Promotes intracellular multiplication of tobamoviruses, probably being a component of the replication complex.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Sequence:
MRRNCCHVSFASTLKILNFVQAFIGVSIIIYSIWMLHEYSRHLPVDPPPSASSSSGTEIATSVSEPLKNPIDFVASIILGSNGGDHGFNLRSLDLPAPWFIYSFMAVGILVCIVTFIGFIAAEAINGCCLCFYSILKTLLILLEAALVAYIAIDRHWEKDLPYDPTGELSSLRAFIEENIDICKWVGIAVVAVQLLSLLLAMVLRAMVSTPKPELDEEEDDENPRSRTWDPLLGPQGNQAPAGSSKIENWSSRIREKYGLNQSPPVNPKG
The following text describes a protein:
Function:
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTEHWGSAVFAARRKHEEDTTRDSIFTYTNTNNTRGPFEGPNYHIAPRWVYNLSTLWMIFVFTASVFTNGLVLVATWKFKKLRHPLNWILVNLAIADLGETLLATTISICNQIFGYFILGHPMCVFEGFTVATCGIAGLWSLTVISWERWVVVCKPFGNVKFDSKWALGGIIFTWVWSAGWCAPPVFGWSRYWPHGLKTSCGPDVFSGNEDPGMVSYMVVLMITCCIIPLGIIVLCYIAVWLAIRSVAQQQKESESTQKAEKEVSRMVVVMIVAYCVCWGPYTFFVCFGTAYPGYAFHPLAAAMPAYFAKSATIYNPVIYVFMNRQFRNCIMQLFVPLAPRCQRPCWAMGIPLCALKRGRRVTGLFTPPTRPARRANSHQALARPVSGHCAASARWSGLACGATRGSRTGV
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MMSSTHTAVKTEFIKEESEEVRIPEPCGDEEEEALTLKKEEPEEHTDQIEVKEEAQMEESEELSDDEDLGDYEPPQFLSCSKIVSRFSQLRVQKGKGFFFSCLECQMSFETKEHLMEHFRVHTGESSSQTHTSTVQKQPMFCHQCFRKFSCRKHLLEHYRIHKVEKPFSCEQCGKSFAYKQSLNNHTKQHSDCRRHVCQDCGAGFSSKDSLTDHMRIHEIKKPFRCDECGKSYTYKYSLRYHQKVHRPPKSFVCQQCGRSYSDKDSLTGHMWSHTGVKAFRCQRCGKSFTIKSSLDQHMKIHSDLKPISWFSS
The following text describes a protein:
Function:
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNALGDVSPHTGPTQLAAGHAPPTPPHEDPLDDIYGSAPGSPSLLGVDPLNLDHPRERTHEILSDLPSRQRALDTDAYREGLSNSKGQYVQEGFDEGYSLGANLGIRVGYILGVLQGFVAAWRGSNDNLFKDTKKVYDTAQKELAIQELLSQQWVTEEGIWNWEVHGVEDDPTFREVAEQHPVVRKWTATVESMAAQWGVDLQAVEKVHGSNEEEQS
The following text describes a protein:
Function:
Putative odorant or sperm cell receptor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS
The following text describes a protein:
Function:
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Displays anti-alphavirus activity during IFN-gamma immune activation by directly ADP-ribosylating the alphaviral non-structural proteins nsP3 and nsP4. Acts as a component of the PRKD1-driven regulatory cascade that selectively controls a major branch of the basolateral transport pathway by catalyzing the MARylation of GOLGA1. Acts also as a key regulator of mitochondrial function, protein translation, and inflammation. Inhibits PINK1/Parkin-dependent mitophagy and promotes cartilage degeneration by inhibiting the ubiquitination and SUMOylation of MFN1/2 by upregulating ISG15 and ISGylation.
Subcellular Localization:
Nucleus. Golgi apparatus, trans-Golgi network. Cytoplasm, Stress granule. Note=Translocates from the Golgi complex to stress granules upon stress conditions.
Sequence:
MAQAAVAVAEVTQLLCAAGGALELAELRRRLRTSLGTDALERLLRDCGRFVVASRAVVAVGAGREAAAAASERLVLAVSSLRLCRAHQGPKPGCTGLCAQLHLCKFLIYGNCKFLKTGKNCRNGHNLKTDHNLSVLRTHGVDHLTYTELCQLLLQNDPSLLPDICLHYNKGDGPFGSCSFQKQCIKLHICQYFLQGECKFGTSCKRSHEFTNSESLEQLERLGLSSDLVSRLLSTYRNAYDIKNKGSALSKVSPSPAGPQGSSERKDSSGPVSPGTPSQEESEQICLYHIRKSCSFQEKCHRVHFHLPYRWQFLDGGKWKDLDNMELIEEAYSNPSKDRIVYTESAAGFHFDNLDFNSMKFGNTLARRLSTASSVTKPPHFILTTDWIWYWMDEFGSWQEYGRQGSGHPVTTISSSDVERAYLAFCAPGADAQAATLKFQAGKHNYELHFKAFLQKNLVYGTIRKVCRRPKYVSPQDVQMKQSCNTKLHGPKSIPDYWDPAALPDLGFKKITLSSSSEEYQKVWNIFNRTLPFYFVQKIERIQNMGLWEVYQWQKCQMQKQNGGKEVDERQLFHGTSANFVDAICQQNFDWRVCGLHGTSYGKGSYFARDAAYSHHYSKSDTHSHMMFLARVLVGDFVRGSTSFVRPPAKEGQSNAFYDSCVNSMSDPTIFVVFEKHQVYPEYLIQYSTSSKPPASPSIFVALGNLFTSRQ