lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. The CST complex inhibits telomerase and is involved in telomere length homeostasis; it is proposed to bind to newly telomerase-synthesized 3' overhangs and to terminate telomerase action implicating the association with the ACD:POT1 complex thus interfering with its telomerase stimulation activity. The CST complex is also proposed to be involved in fill-in synthesis of the telomeric C-strand probably implicating recruitment and activation of DNA polymerase alpha. The CST complex facilitates recovery from many forms of exogenous DNA damage; seems to be involved in the re-initiation of DNA replication at repaired forks and/or dormant origins. Required for efficicient replication of the duplex region of the telomere. Promotes efficient replication of lagging-strand telomeres. Promotes general replication start following replication-fork stalling implicating new origin firing. May be in involved in C-strand fill-in during late S/G2 phase independent of its role in telomere duplex replication (By similarity).
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MESNSSQCEDETPSLLWGLDPVFLAFAKLYIRDILDLKESGQVQGVFFYNGHPIKQVDILGTVIGVREKDAFYSYGVDDSTGVINCICWKRLNNTKSSSATATPSARELSLTSQLKKLQETIAQRAKLEIGDIIRVRGHIRMFRGEREIHATTYYKVDDPVCNVQIARMLELPAIYRKVYDQPFHSPALKEDEALSNPGTLDLDSLTCLLSEKAKEFLVENRVQSFYQQELETVESLLSLANQPVIHSACSGQMGFKNDTTSRAIHSIFRNAVKLLQEEGLVFQKDGGFDNLFYVTREDKELHRKIHRIIQEECQKPNHVEKGCHFLHILACARLSLSPGLSEPVLQQVLQLLEDQSDIVSTTEKYYTAF
The following text describes a protein:
Function:
Polylycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Involved both in the side-chain initiation and elongation steps of the polyglycylation reaction by adding a single glycine chain to generate monoglycine side chains and by elongating monoglycine side chains to polyglycine side chains.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MQTRPSSEPHRSRDQVTDGDRNRDQPQKCASATLAKKPVTPPAAPPPTPSNRVVAPLTVPVIQLTPAQSDSPVKLARPATPKETAISVPDHSNKENQPARTPPPSKSCPLGAPTNYVARRTWITTERMNELRRKAQEAAKQNKIFTIRGCFNSVRNALLMRGWVEKLDVHRKVMPAGQMTYEDLTQRLPKRKAGETRRQYVQKCERNIMSRFLEHMPVDFLWTNRKEKCDYIDQAKNPGMTINKFHRAPFTSKEGLCSQLRDFHWFFEEGTAEMYFPRCYNVWSPEELGEFIENFKLTACVAFLRAMLCKYHKQGSDAVFSCSGKIPYSAIDFAYKRLVEYIDSCQHNDIDFEDPPKIWEHDWDAFLFQHQQLVNEDGRIQHDGGQRLEPMVKSCLSLVDKMKVHWPQYSLDGYQNMWIVKPANKCRGRGIILMDNLKKILGVVNLSIASKSRYVVQKYIERPLILFQTKFDIRQWFLITNTQPLVVWFYRESYLRFSSQEYSLSNHHESVHLTNYAIQKKYTNGKRDKRLPSENMWDCYSFQAYLRQIGKYNMWLERIFPGMRKAIVGCMLASQENMDRRPNTFELFGADFMICENFYPWLIEINSSPDLGATTSVTARMCPQCLEDVVKVVIDRRTDPKAELGNFELAYRQVVPPTPAYMGLNLFVKGKQVLQKANHGGGHGHYYYQQQRKERSLATSSVYRQRSAIIHPATSISRIHRAMPTFNATEYMEKYMVEPLSSSRSSLCSQLPQKSPSAAPALTATPSGATSSYILKQAGRSITQLLSATHKRNTGGSLSGEQVQSTALPPKRQRSCGPRLSSTNPVESTEKKFKILIKNYSSNGNENMQDARPEVANSATATAISERKWRSLRNIAATAGGSSNLAARSKGPPLIAPPSLPTRRLTRTKSEIDSTGMHAIGRTFGRKSNGPRLPISISVQALHRGEPIVAALKQATSELQLSQAQMMSPRTALANKLNGSTLMVPASALPVG
The following text describes a protein:
Function:
Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.
Subcellular Localization:
Nucleus.
Sequence:
MPANKPILKTSLPTAHAASSTAALQKPNNARRAPPKSKALEQQKGQPTNRPNVDPRHLAIAMHHAHQIQAQKDTEALILDRILELVNFPSSLTVDPAAPSAEDARAFKAALVPFQPADYDNLILERNIEGLCGYGLCPHEHRKEDTKGKFRITWGAKGSGPGGRGREMNIVPKEKLEMWCSDECAERAMYIRVQLAEEPAWERRDGRHAKELVLLEEDRARARKGKSKMSSSATLKEVTGQLEGLNMEGTEGPNDLANAISGISLDAARFRELAMERGDANPALQAGRVDIAIRENEGLSQHVTPPQMRPGDDKGGSIEGYVPKEI
The following text describes a protein:
Function:
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
Subcellular Localization:
Nucleus.
Sequence:
MGVSGYTRSASSLIADVDIESDHADITEHTLTNESTYGDVHRMFLQGLMVRQVMTVTDATELYTKIAQQEKTSMLGLAAFVNQINAELGNKVGLEVKRGIDPNTGKDTLVLINIHTDELAQLAAAYTPSEVSFFKKMIELLIVEKSNGLYELSSLKALRAASHVKPALTKENAEMLISRLVQDNWLLDRNGKLTLGVRSIFELRPYLLEEYPEDIFECSSCFQILTTNTTQCANNECNVALHQHCVFKVFGDRAIRNCYKCTTPWPVTLEHQQDQTVNNHGESIEENSAPVRDQFTQDKDEVDTDCMSNSGDEQIVESRSAKRKQMST
The following text describes a protein:
Function:
Choline transporter.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MQEQQEQRKSTDLICFWLFSLFQGFFFCVTIYALLNGNPNKLGLPFDPDRKQFYSNFYIDSSCGFDLEQYKYIYFTTPSKNFLQRTVCLSECPNKQQICSTKLLCSPNSIVKSCQINPSVTNISESILAYPSEAYNSQICLPKNPDYLNEIKEYIVPSFNQRLGSGLRDLKWVILGISLISVIIRQQFMLTKIVTHIFWGYFLIIVLSLFSLCFLSAQQYYQSQEQLLLDQQLEINKLISFANSLEICQKLYQIVIIISIIAIILSIIYAIYLKSQTILLNSFIKVGGDFIKSNITCIIAPFVGAVIIMLYSFVWIEQQLYLLSNLKTQDIKYPYFQLNFASGDQALIVMNFLIYIWTLVFILGLIEFLTSGMVCEWYYQQGNRVNFEKKNVLSNLIKYHIGSVALGSMLITTFKFIKQILNTTKLCQGFQNRILYAISKHNYVIMNIQPNHFLDCGIIVRELIIKEIDTFNKIGELGQSFLEISRLSMALFCQSICMLIIQDHPYSIILSLYCFVIAYSITSLFISIYGQSSEAIYMLYLYSQKHLSQEDNPQCTIVRSLQYNYRLYNQCLISQMTILIKCNDVQFSILHILYCLIQIQKWFLSSQSRYIHSHHPSMILLLFLIKSVKIQNH
The following text describes a protein:
Function:
Sequence-specific DNA-binding protein that interacts with enhancer elements to regulate transcription of selected genes (By similarity). Required for neuroblast and epidermal morphogenesis, perhaps acting in cooperation with transcription factor aptf-2.
Subcellular Localization:
Nucleus.
Sequence:
MSYYPYYQTENSDYSSFNSLMADICEPSPSSSSSRKRPADSENGNSAKMPVVIPMQPVQNFTMQYPIDNGWQNFNMIHQVYNNNNMNQPGYGWVGQPPPMPQDFYKARPGQTVTPPMNEFHNAHGTQQTPNDNSGNLPISSVMYTPESDLSTTSANFTPDWNTTTNGPCNQEKRNKENLFPNDDTSSGKLFDYFLTNTERENESENNIPHPYNKAVFPTFGVPVSSDGNVVAEVVDGRLPAVGTRSKYDLTVDELRRRCGAPEHMNQSALYCFFRKSKKKEAINRVKKVLTDYNITVRTMQRQRKVTCFSPFLEEEATALARDLDSITEEFLPIDAIALEMLEKLIFNNKNLDICLRILKNTNKTITRVIKTLEVRQPKITGQKEKLKGNSLDLSYHNFSLTTHGFGHPNSLSHYRSYQKIVEQAALYCEKMQKGASLPSKEYLIPGQKPFENMSNEFFVEWRMRSYHKKARKEMLDFNQAYSRSS
The following text describes a protein:
Function:
Plays a role as a neuroprotective and antiapoptotic factor.
Subcellular Localization:
Secreted. Cytoplasm.
Sequence:
MARRGFSCLLLSTTATDLPVKRRT
The following text describes a protein:
Function:
May act as a soluble regulator of keratinocyte differentiation (By similarity). May play an important role in embryonic skin morphogenesis.
Subcellular Localization:
Secreted.
Sequence:
MKIPILPIVALLSLLALHAAQGAALGTPMEDTTSSNYPSGTEGLSEFLNFNKLQSAFKSDDFLNWHVLTDMFKKALPFINWEFFPKVKGLRSAVPDSQ
The following text describes a protein:
Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence:
MDPCECSKIAGSCNCGGSCNCSNCACTSCKKSCCPCCPSDCSKCASGCVCKGKTCDTSCCQ
The following text describes a protein:
Function:
Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, antagonizing the rnf8-dependent ubiquitination at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating numa1. Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor ifnar1; deubiquitination increases ifnar1 activity by enhancing its stability and cell surface expression. Acts as a regulator of the NLRP3 inflammasome by mediating deubiquitination of nlrp3. Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in ifnar1 deubiquitination.
Subcellular Localization:
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs). Interaction with abraxas2 retains brcc3 in the cytoplasm.
Sequence:
MAVQAVHIQGDAFLVCVTHSLSTEREEVMGLCIGEVDTQKLVHIHSVIILRRSDKRKDRVEISPEQLSAATIEADRLADITGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDVGFVGLIFSCFIEDKNTKTGRILYTCFQSVQAQKSSEYERIEVPLHVVPHNTIRKVCLESAVELPRILCQEEQDAYRRIHSLGHLDSITKIHNGSVFTKNLCGQMSAISGPLLQWLEDRLEQNRQRAQELQSEKEQLLQELKTLG
The following text describes a protein:
Function:
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
Subcellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein. Note=Localizes to the transition zone of primary cilia; SEPT2 is required for localization to the transition zone.
Sequence:
MAFYDVYAHPALIRYRTCVCTRATLFVCVVLGLTYISPLLVAYRSQGFWLKRNSYEEQPVVKFQYDLILLGVTDTTGNYLAWSTFPNFNRLIGDNLRIPEISAQEEDKNQDGKSDVLLLQISVPLKPAEQMFSVQLLLTFSYQLFRMSTVVMQTLAFIQHSSPVPGSQLFICGDLRLNQRTPLPHRGLHSTYNVSVIDGSSPFASTYDLTNIIRLYQQRNLTTHLSGVIPVWTVGRAANAPFQISAQIHYPVEMIDYRPGFWETIKFAWIQYVSVLLIFLWVFQHIQTFIFQNQVLPTITIPPFKQHRS
The following text describes a protein:
Function:
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42.
Subcellular Localization:
Nucleus.
Sequence:
MTDTFENDSKAFSDFLAGDLKYEISPKIAIHDYRSDHQGRGVIASEDIEEDEVLFKIPRSSFLSVENDPDFIKQVPEAKKLNSWLQLILYMMKAGSMTKWKPYFDVLPTQLDSLMMWTDDELEGLKGSMIVKKIGKAGAEEDYQEKLKPIIDAHPEYFKDCDTSLESFHRMGGLIMAYSFDAPDSFSEDEEDDEDIEHDDLYNEGLVKAMVPLADTLNAHTRFCNANLIAEDDGGFSMTAIQPIKKGEQVYNTYGELPNCDFLRRYGYVENEGTEFDIVEFSMDEISDFYANKASKDLIEEATDLLEDWQGEYEIMDEYFVVGKTGEIEFDLACFISFLELITKDTSLLSKLKQDKSLRKQVVKQLWKKSNQGLLIDDAVKSLTELVESKKKTYGEKSDKTHKHKMASIVLEGELEILDNIVKRLPETTTYVTDDILTKKRASDAPSGDAKRKK
The following text describes a protein:
Function:
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
Subcellular Localization:
Cytoplasm.
Sequence:
MVENVIWPAYFDAALSRRDGRRVPMELAVEEPSIDEIATAVQQVGYDAVVERDVAYPRRHWDAAGRVLVKDADDAKNTLVQAVAAYVGALRD
The following text describes a protein:
Function:
Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex. Contributes to nuclear and centrosomal positioning prior to mitotic entry through regulation of both dynein and kinesin-1. During G2 phase of the cell cycle, associates with RANBP2 at the nuclear pores and recruits dynein and dynactin to the nuclear envelope to ensure proper positioning of the nucleus relative to centrosomes prior to the onset of mitosis (By similarity).
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: Due to intron retention.
Subcellular Localization:
Golgi apparatus. Cytoplasm, cytoskeleton. Cytoplasm. Nucleus envelope. Nucleus, nuclear pore complex. Note=In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Localizes to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae in a RANBP2-dependent manner during G2 phase of the cell cycle.
Domain:
The fourth coiled coil region is involved in Golgi targeting and in the interaction with DCTN2.
Sequence:
MSAPSEEEEYARLVMEAQPEWLRAEVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELEVDYEAIRSEMEQLKEAFGQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTELKQLRNVLTNTQSENERLASVAQELKEINQNVEIQRGRLRDDIKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAIRLKEISERQLEEALETLKTEREQKNSLRKELSHYMSINDSFYTSHLHVSLDGLKFSDDAAEPNNDAEALVNGFEHGGLAKLPLDNKTSTPKKEGLAPPSPSLVSDLLSELNISEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHEDGDYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLYHHVCMCNNETPNRVMLDYYREGQGGAGRTSPGGRTSPEARGRRSPILLPKGLLAPEAGRADGGTGDSSPSPGSSLPSPLSDPRREPMNIYNLIAIIRDQIKHLQAAVDRTTELSRQRIASQELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLELLELDHEQTRRGRAKAAPKTKPATPSL
The following text describes a protein:
Function:
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Subcellular Localization:
Cytoplasm.
Sequence:
MEDVKELIVRLAAENALKYGKADTKAVIGKILYMRPDLKQNVRELIPLVEEAVRAVNEMPKEALEGIVGEVKKEKKEEVRKWPDLPKAERGKVVTRVAPEPNGYPTLGHAKGLLVPFIYARLYDGKFLLRFEDTNPRVERLEYYEAIRNEFSRLLEACEEELGLSPGRWDEEIIESYHLEEMYSLAKKLIEAGKAYVCTCPAAEVRKRRKLGISCDHRDQPIEKNLELWEKMLNGGFREGEAHLRLKTDMSHPNVTMRDPGIFRVIEAEHPIHGDKYRVYPVYDFSVSVMDSLTGVTHAFRSKEFEPHVDVQRHIVRALGLREYEMIQFGRITVEGIPLSKRYIRPLVESGILEGWDDPRIPTLRGLFRRGINPRAIVRFFYELGPSKVDATVNMEAIASINRKILDPIAERYMFVPNPIKAKIEGLTPPVIAQVEVHPDSKRKREIRLDESEVFIASSDLEGLKPGDELRLRGLVNVTIRSVNPDEVSLRVSEEQRVKGVKIIQWAPVRNGVPARLFVPESPYSFRMLGGYGEPALRGIKEGEIVQFVRVGFARLDRRDPLTFILSHD
The following text describes a protein:
Function:
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MHLFLSLLLLSEMTLLFALVFSSSKLRELITKMLDKIVEGKGGAISLPVVATLTVVFISMVYDAKGIWTEDVVLNAADEVLMVNLVLKATLMGFALYLALLTYGFHKYIKGSRPWEAAKEKN
The following text describes a protein:
Function:
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
Sequence:
MTTFFPITRAAMADLPTRFGHFQIVVYLDAEQKEQIALTCGQLHTPEPVLTRLHSECLTGDIFGSHRCDCGEQLAAALTAIQQAGRGVLLYLRQEGRGIGLVNKIRAYALQQQGLDTVDANRALGLPDDMRDYRVAAAILTDLGIKSVRLLTNNPAKITGIEQHGIAVTERVPLQMPANNYSAAYLLAKQVRMGHLLDSRLL
The following text describes a protein:
Function:
Involved in the regulation of peroxisome number, size and distribution.
Miscellaneous:
MISCELLANEOUS: Present with 5040 molecules/cell.
Subcellular Localization:
Peroxisome membrane; Multi-pass membrane protein.
Sequence:
MDSVTNFFWNDTYNAGTPTRSTLKGKKVQNGIDGKSQAKKESISSGSRTSDPTRGSLPSSSGQPTSGGGFPSTSNIQKMMADTLVEKIIKMALPPSSKTAVDTIHHRMVAGKERPKLSVQITSRNFIQMNSRLGVPFMIMDELIKILNWTNPAYTVSIMFLYTLIILKPFQMLSSLPIFYLLFCVMVPQYLYIHKPNPTSYLDNNQTPAQGPPLRRPEVPKPVPELSQEFVLNLTDLQNHMLLYVKFYDFTLLILQKFAFFTNEAISSFYFIVLLIIATLNFLYMDKFIKLIPMRPVLILLGWGFFIASHPSNREYLLTKLNSEETRLKTLTISTNLESKILQHLKLIEAREHRLVMIFEIQKYLPEYKEWRPVGFSDDDYSLFSSLRIYQRRIEENSVKSLEEIEPPKDWEWEANSHWVLDLDPKEWVEDEFIQYVEIDSETKWVYDLNLDGQRGSYRRRMWTNSCVRKKLDSGISSNLGEEEVVNPLREETYRQGVHGVTKGSMSGGLTHSSDDDRADEESINGTIPNLNNIDADASYPSIEELTDTLNSTI
The following text describes a protein:
Function:
Required for protein transport from the ER to the Golgi complex.
Subcellular Localization:
Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Sequence:
MDIFHKSYNVILSPPKVQQADETISKLCDRLEHATLFEDRKAAALGIKSFAREFKELVAAHGLKGIIQSLHRDYDDPELLKVTLETCLILTRHDDDSRASDTGLWIADQFILNQDNIQCLLQSISHKDFYVRLYSVELFSAILSCRPTELKDCLQTFPSAISSIMVPLRDSIEPVRNADLYFLSELVKDCTSIQKLVVFENAFETLFSLLENEGGVDGGIIALEALKFLNVLLKDNISNQNYFRESNHIPSLLKLLSVDTFVDGTWDTSRVQCVIEALYALQSLVPIGLSSSIANQNAVVSNHGIDVLLTLATHPDLLFFDVQKISWITLAHVVYSNARAQNSFVDSTFFDIKNTDVLTCLFDYLFLSSISPSHRYSVAFFLRSLTSENDELSSKFLKQIIHAYTHKQDNRLNIIQGYLDLVHLSDQDQYDNWFTSTILTYLVIDNDQRKYLLCSIPLFQDMDNDEDSESEDKVTFIQCVSTKLIATLRHENALQNCVGYLTLLIALVYGNPDSVKDFLSESSILQTFLTALMDESSSANSVIQGMIAVFLSLVYYYCPIESPVSKSDVYNAITSAVKRDVFINRLQRLRRMNLYEITFLSMKQKMHAIDDAADAFNTKIGEINTLDAFDEAQKQLKSLREEIDNTKEALDLSVKERSIQEEKLNESLKTSKTNLEEQTQLAEKYHEELLDNQQKLYDLRIELDYTKSNCKQMEEEMQVLREGHESEIKDFIEEHSKLTKQLDDIKNQFGIISSKNRDLLSELEKSKSLNNSLAALESKNKKLENDLNLLTEKLNKKNADTESFKNTIREAELSKKALNDNLGNKENIISDLKNKLSEESTRLQELQSQLNQDKNQIETLNERISAAADELSSMESINKNQANELKLAKQKCSNLQEKINFGNKLAKEHTEKISSLEKDLEAATKTASTLSKELKTVKSENDSLKSVSNDDQNKEKSVNNEKFKEVSQALAEANEKLNARDEEIERLKVDIIGLQNASLNMQSLKDSDNRTISDLESKNKELEKKLKEADEYWLLIVEELESKRTKDKELLRQCGQAVSEDEQSEEE
The following text describes a protein:
Function:
Multicopper oxidase that may play a role in the maintenance of inorganic phosphate homeostasis.
Sequence:
MVKGTFLGMCVLLVAAAAAGEGKGQKQGVPLLDAGRLEKFVDELPDMPVLHGYGVAERGRLVAGELIIGMYDTIWKFHRDLPAMRVFAYGASRETATVPGPTIVAMKGVPTRVTSLAAAGLGNGTVVPTVTHLHGGVQQSTSDGNSMAWFTSGFAATGPHFSSPAYEYPNQQPPGNLWYHDHAMGLTRVNILAGLLGAYRVSDPAAEAPLGLPSGEEFDRNLVLFDRDFRSDGSLFMNATGNNPQVHPQWQPEYFGAVIVANGKAWPFLRVRRRRYRFRILNASNARFFRLSLSGGLCFVHVGSDSVYLARPVPTKEFLLAPSEIADVVVDFAGAKDDAATVRPSAPTPYPGDHDKKAETPEHDPSAMPAALMPWYPKPDAREAVVTRHIAMYKYAKKGTDEPTHMYLNGVPYMDPLWEVINLTDDDNHPLHGHLAVFAVLKQRSLQRVNELRDCTQGSASLPESRKMAQKTRAYAPFSMISIHIN
The following text describes a protein:
Function:
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.
Subcellular Localization:
Virion. Host nucleus.
Sequence:
MSLLHTFWRLPVAVFFEPHEENVLRCPERVLRRLLEDAAVAMRGGGWREDVLMDRVRKRYLRQELRDLGHRVQTYCEDLEGRVSEAEALLNQQCELDEGPSPRTLLQPPCRPRSSSPGTGVAGASAVPHGLYSRHDAITGPVAAPSDAVAASAAAGASSTWLAQCAEQPLPGNVPNYFGITQNDPFIRFHTDFRGEVVNTMFENASTWTFSFGIWYYRLKRGLYTQPRWKRVYHLAQMDNFSISQELLLGVVNALENVTVYPTYDCVLSDLEAAACLLVAYGHALWEGRDPPDSVTAVLSELPQLLPRLADDVSREIAAWEGPVAAGNNYYAYRDSPDLRYYMPLSGGRHYHPGTFDRHVLVRLFHKRGVLQHLPGYGTITEELVQERLSGQVRDDVLSLWSRRLLVGKLGRDVPVFVHEQQYLRSGLTCLAGLLLLWKVTNADSVFAPRTGKFTLADLLGSDAVAGGGLPGGRAGGEEKGYGGRHGRVRNFEFLVQYYIGPWYARDPAVTLSQLFPGLALLAVTESVRSGWDPSRREDSAGGGDGGGAVLMQLSKSNPVADYMFAQSSKQYGDLRRLEVHDALLFHYEHGLGRLLSVTLPRHRVSTLGSSLFNVNDIYELLYFLVLGFLPSVAVL
The following text describes a protein:
Function:
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
Subcellular Localization:
Nucleus.
Sequence:
MPQVKIIAKNFMDMVASLTAIKLDKLYNNVFICEAILRSLPPLAKKYVLQLLFIDDPVPCTRIEEWVLPGGLSKHRVAIDRLIQLRIFTETVDRREGTCFSLNPTFQNNLQKHIISGGVLPREPMNSSNGIKLPSLQELETYALQQWECFLLQLINSGQGEKLTGISSSMMKVFQRGLLSQRDRDGPRLTESGFQFLLMDTNAQLWYIIREYISNAEERDVDPADLISFLLELSFHVTGEAYNLNTLTDVQRTTLKDLADLGLVKLQQGRKDSWFIPTKLATNLSVSLADSSVRKEGYVMMETNFRMYAYSTSKLQCEILRLFARIEYQLPNLIACAVTKESLYNAFDNGITSDQIITFLQQNSHPRCADRVPSIPENVTDQIRLWESDLKRIEMTQAHFYDEFPSKDVFEGACNFARQWGGLLWEDSKRMRLVVKSEVHNQMREYLHTQGN
The following text describes a protein:
Function:
Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPFTEEGKYQTFPSKSAPISGNKFQKMATIHKEQEKSGKFYENQRKIHFGGTPRIQYREGGKFYKPPRNEQDPEKSGKFAGKTGKKLEMKKKLKSKKVKGDPVKGTSTEYDQLANSDEDNDVMDVSDMLPEPEDEVESEIPLVNTGRKATGKEKNPAEKKSRKFNALGEFEDVEEDAEAAPAPPAPKKPKNQNVEEEGSEDELERSEGSEGSEEEEDDEDERLKFREEISKMPLGKVKEMKEKLGIKLFNKTYFGTSEADKKRADEKKKAAEKADKGQHRPREMSSKRPVSAFRNIYGGHEQEKKKKKWDPRFDARAGDFKEVCFENNYQFLDEIRTGEMQDLRNEYNTARAEGDEKKAERLKNTLHKMETREKTRAEKRRHAETRKELHDDNIERMLRGEAPIFRTKAQVRRIDAEKKYEELKKDNKLDKYLQRKAKKESAKQKKARPFEGYGFQN
The following text describes a protein:
Function:
Probable transcription factor involved in the regulation of flowering time in long-day photoperiod. Participates in the repression of FT expression and floral transition, by interacting closely with the FLC-SVP pathways. Functions in the satellite meristemoid lineage of stomatal development.
Subcellular Localization:
Nucleus.
Sequence:
MGRGKIAIKRINNSTSRQVTFSKRRNGLLKKAKELAILCDAEVGVIIFSSTGRLYDFSSSSMKSVIERYSDAKGETSSENDPASEIQFWQKEAAILKRQLHNLQENHRQMMGEELSGLSVEALQNLENQLELSLRGVRMKKDQMLIEEIQVLNREGNLVHQENLDLHKKVNLMHQQNMELHEKVSEVEGVKIANKNSLLTNGLDMRDTSNEHVHLQLSQPQHDHETHSKAIQLNYFSFIA
The following text describes a protein:
Function:
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
Subcellular Localization:
Nucleus speckle. Cytoplasm. Nucleus.
Sequence:
MFGVLNSSDHRAAVQQRNIPAFGRTSFELWTDNPTSNYRCETGGNGRDSGQNRVRRPMNAFMVWSRDQRRRVALENPQMQNSEISKQLGYQWKMLTEAEKWPFFEEAQRLQAMHREKYPDYKYRPRRKALPQNSDKLLPAASSSMLCRQVLVDEKWCPFTYRDSCSRAAHPRMEDQLSSSQPVNIANSLLQQEHHYCSTSLRDSPETLAMHLSADPPFYPK
The following text describes a protein:
Function:
Guanine-nucleotide exchange factor for ARF3 required for localization of ARF3 to the bud neck and tip and involved in actin patch polarization.
Subcellular Localization:
Cytoplasm. Cell membrane; Peripheral membrane protein. Bud neck. Bud tip. Note=Localizes at the cell membrane only at the bud neck and bud tip and this localization is ARF3-dependent.
Sequence:
MCASLNEVKKNDTYGVSQKGYNDNFSESEGVLHGSKSMPTSMKNMLQSPTMVNMCDILQNKEAANDEKPVIPTTDTATAGTGTEDISSTQSEETDQNSHLIASEILEGTFKDVSYKEYANFLGNDNNNQVLTEFVKLLSPLPSSLLETLFNLSKSIYFIAEAQNIDRILECLSIEWIACHPNTHWKSGYKSCHIVLFSLLILNSDLHNNFQVDHKKIKFSMVAFINNTLRALREENEYEELKIYSREHLIIEELSEYYKTLNETPLPLCTESRTSINISDNQSSLKRFSTLGSREFSTSNLRSVNSNSTTLYSRDGQVSVREMSAKSNKNFHNNHPMDALYLKESFDDGLITENGSSWFMDDLILISKKSLPRKYSKRDKDQVAAPKMTSKRNKSFFGWLKPSKTTTLIEHTSRRTSLSYLNKDSEWERVKIQVKEGRIFIFKIKPDVKDIIQSSETDSATIDYFKDISSSYFAYSLLEAEAHVVQDNIIIGSGAMKSNVCNKNTKRKSGNFTVSFPENINGPKLVLEFQTRSVEEAHKFMDCINFWAGRISPVPLTQFEAVSNAEYGWSDKILTEHASLNLKNIVVSEWKPLLGLELLYEDAKDVEMVELKERLKELMNFTRQLGIWIDKHNEIKDKLVEIWSFDDNYFEAVMNNWNSRYLYMNNQYKKRLSYLKALQKAMGSVQF