lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Overexpression in M.smegmatis increases resistance to erythromycin, ampicillin, novobiocin and vancomycin. It also reduces accumulation of ethidium bromide in the cell.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Domain:
The ATP-binding domains (NBD) and the transmembrane domains (TMD) are fused.
Sequence:
MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAIAADHRPLAPWAVVLVAAAGATYLLMYVRRYYGGRIAHLVQHDLRMDAFQALLRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAVMTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDAAVCGIRVVKAFGQEERETVKLVTASRALYAAQLRVARLNAHFGPLLQTLPALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQQARAGAVRVLELIDSRPTLVDGTKPLSPEARLSLEFQRVSFGYVADRPVLREISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRELTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIEEFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSAVDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVGTPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTNVHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRHGIDVGIRRHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQVLFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVAVISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRARHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGELAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAARPVGTLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTLIKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRDAIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQLQLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVAHGLAIAEHADRIVVLEHGTVVEDGAHTELLAAGGHYSRLWAAHTRLCSPEITQLQCIDA
The following text describes a protein:
Function:
Transcription factor required for sexual development and entry into stationary phase. Binds and activates CRE sites (cAMP-response elements, also known as M26 meiotic recombination hotspots).
Subcellular Localization:
Nucleus.
Sequence:
MSPSPVNTSTEPASVAAVSNGNATASSTQVPENNQSDSFAPPSNNSQQNQQSSTIAPNGGAGSVANANPADQSDGVTPSFVGSLKLDYEPNPFEHSFGSTASVGQGNPSLNRNPSLSNIPSGVPPAFARTLLPPVSSIASPDILSGAPGIASPLGYPAWSAFTRGTMHNPLSPAIYDATLRPDYLNNPSDASAAARFSSGTGFTPGVNEPFRSLLTPTGAGFPAPSPGTANLLGFHTFDSQFPDQYRFTPRDGKPPVVNGTNGDQSDYFGANAAVHGLCLLSQVPDQQQKLQQPISSENDQAASTTANNLLKQTQQQTFPDSIRPSFTQNTNPQAVTGTMNPQASRTQQQPMYFMGSQQFNGMPSVYGDTVNPADPSLTLRQTTDFSGQNAENGSTNLPQKTSNSDMPTANSMPVKLENGTDYSTSQEPSSNANNQSSPTSSINGKASSESANGTSYSKGSSRRNSKNETDEEKRKSFLERNRQAALKCRQRKKQWLSNLQAKVEFYGNENEILSAQVSALREEIVSLKTLLIAHKDCPVAKSNSAAVATSVIGSGDLAQRINLGY
The following text describes a protein:
Function:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
Subcellular Localization:
Nucleus.
Sequence:
MDKEPKAATEDPKVDLFEDDDEFEEFDIDQEWDDKEEGKEIAQQWEDDWDDDDVNDDFSLQLRKELENNSEKS
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification (By similarity).
Subcellular Localization:
Nucleus. Chromosome, telomere.
Sequence:
MTSEVIKFPQFPEFTIHISLFINVSSENITTIKSNLISATDNDHNKYDYCFLNTKYIISKEHLFQSIYKSLLNYTSKLGLSTRNLKSEIIYNLSPINNVGDALKRFGISEDCPNCIVIKIINNNNKENSEETKISEKVTTDLKEIIDGELIELNDQYIFENFIDLAKFRKLYKLNDVVDLNKEDNLQGRLTRLAIGACILRGY
The following text describes a protein:
Function:
Exo-type enzyme that specifically cleaves the non-reducing terminal glycosidic bond of chitooligosaccharides. Catalyzes the hydrolysis of GlcN-GlcNAc to glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). Involved in chitin degradation. Can also hydrolyze reduced chitobiose (GlcN2OH) and chitooligosaccharides of various chain lengths.
Subcellular Localization:
Cytoplasm.
Sequence:
MGKVEFSGKRYVIDGEPVTIAGGTLQFFRVPADAWKDRLLKMREAGLNTVDTYVAWNWHEPEKGSFDFKGETHPQRNLVGFLELADELGFYVIIRPGPYICGEWRNGGIPDWLIDEHPEILAKGPNGPLPRDIYYPPITYLHPTYLEAVGEWYNAVFPVIRKYLYTNGGPIISVSIDDEPSYWETIFQPFLTDYNEIITKPGGLWEKWLEQNYTLEDLRRRYKGDFKDYSEIKVPTSFSEPLPKLIDWHHFKLWMINEYVRWIYERMAREFDVPISILDPYLLQVAWRHFFTYMREHNLKIHVWTEFWYSFYRSSDFKEDKLGHIYYKTGIYRYHVRKAGTPPLSIETQSSLAHTIDPTEAELLYSILPPLGIPNINYYLFVGGENPEGYESHNGITWDVYSPVGLDGSERPHFGVIKALSETMTSAEGLADAELRPKVAVGLYEPYEALNLWGYEGLEESTDLNEYLLGERGLFTLLAMSNTPFDAVDLEDVTLDELLSYDQLWVYSLDFMSREVQDKLVEFVARGGNLVILPMLPRYDENLEPYSSLKDFLGVEVEREKARRNPRLIQFLSVSAEGIDRMLVRNTVRGVRGGEPIAFLGEKPVGAFVRKGGGSAVVLGFRLQYYTSHHDLHRKFVWKLKELQGVREDFEVTNPDMIVLPMEGKGYAYLAVTNPRGHPIKGRISYRGLEVPVLLDGIELKRRGTLYLPFGVRKGDVEVAYATATLVMWEGDVLTFRNHLSGHSEIALKGVESVKVSGGKIVDGSDGEVLRIVIEHPGEYFEVELL
The following text describes a protein:
Function:
Plays an important role in the control of DNA replication and the maintenance of replication fork stability.
Subcellular Localization:
Nucleus.
Sequence:
MNEQPMPINDEETLFDGNIPSTANGLQDEKEIQAIENGLKRKVIRQPRPKLDSDRLTSERGLRALHQQFNKLHFKKKKDYHNNLITILRIYEHWAHRLYPKLPFVDVVHKVENLGSKKAVQYALSLIRLGQNDHYFQQDIDDNDNGDFNNDVQEYQQDTSTRKLSETNDLELTLSDDTNNKENEYSNKS
The following text describes a protein:
Function:
Member of the two-component regulatory system CiaH/CiaR. Involved in early steps of competence regulation and in penicillin susceptibility.
Subcellular Localization:
Cytoplasm.
Sequence:
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVYFLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGYLLKDVQ
The following text describes a protein:
Function:
Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
Subcellular Localization:
Cytoplasm.
Sequence:
MDYLIRGISMDKRIVAYVARTTDLVEQARKIHKASPTAIAALGRTLTLAAIMGKMLKKDEERISLQITGNGPLGNIFAEADPKGNVRGFIKRAYIDLPPTPDGKLDVPSAVGKDGTLSVIRDLGLKEPYRGVVPLISGGIAKDLAYYFTYSEQLPSAVAAGVYVNKDGRVISAGGYIVQIIENADNDMVDILESNIKNLDPPSKMILEGKTPEEIMSKIFKDIDYEQFSREYLKYSCRCNRERAENTLIALGIKELEELIEKEKSIEVKCEFCGKIYIFNKNNIEEIINQLKNKT
The following text describes a protein:
Function:
Putative component of the machinery responsible for pumping aminotriazole (and possibly other toxic compounds) out of the cell. Probable ATP-dependent export permease. Appears to confer resistance only to aminotriazole.
Miscellaneous:
MISCELLANEOUS: Present with 1720 molecules/cell in log phase SD medium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Domain:
Deletion of the C-terminal 34 residues abolishes ATR1 activity, while deletion of the C-terminal 23 residues have a minor effect.
Sequence:
MGNQSLVVLTESKGEYENETELPVKKSSRDNNIGESLTATAFTQSEDEMVDSNQKWQNPNYFKYAWQEYLFIFTCMISQLLNQAGTTQTLSIMNILSDSFGSEGNSKSWLMASFPLVSGSFILISGRLGDIYGLKKMLLVGYVLVIIWSLICGITKYSGSDTFFIISRAFQGLGIAFVLPNVLGIIGNIYVGGTFRKNIVISFVGAMAPIGATLGCLFAGLIGTEDPKQWPWAFYAYSIAAFINFVLSIYAIPSTIPTNIHHFSMDWIGSVLGVIGLILLNFVWNQAPISGWNQAYIIVILIISVIFLVVFIIYEIRFAKTPLLPRAVIKDRHMIQIMLALFFGWGSFGIFTFYYFQFQLNIRQYTALWAGGTYFMFLIWGIIAALLVGFTIKNVSPSVFLFFSMVAFNVGSIMASVTPVHETYFRTQLGTMIILSFGMDLSFPASSIIFSDNLPMEYQGMAGSLVNTVVNYSMSLCLGMGATVETQVNSDGKHLLKGYRGAQYLGIGLASLACMISGLYMVESFIKGRRARAAAEYDCTVA
The following text describes a protein:
Function:
Endonuclease that probably plays a role in the DNA damage response and DNA repair.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MADASSLSLQLLAALREEEARAVEKLLRLGADPNLVLDDGAAAVHLAARASHPRALHCLRMLLRWGADPNARSAEALTPVHVAAAWGCCSALELLLSRGGDPTLRDQDGLRPLDWALQQQHHNCARVLRELDTPTRKPNETPKPTAGSPGASQDSELHMHRAELEVEAVEVAVQPQSPEATESSDYSSDASFVTAVEDSLQPRRPGGICELMASLWVTRGAASAGEGAPNCQSQALTLTEKSTDKPLLLGDGDLGALHPHGSVPPMSDLQLLQALRALGYSPGPVTPFTRGHYLRRLQEAQASPGHSPELAEALRTGTVPDCQVDEAALAQHFQRPDPSRKWREGITKSSFTYLLLDPRLTKDLPARASSLTLAQCLQCFVRAIFYVGKGTRARPDAHLWEARGYHDQPRKQVCPKIRRILDIWDSGRGIISLHCFQHVVAVEAYTREACLLDALGLQTLTNQKQGHYYGVVAHWPLPRRRRLGVYLLQRALLVFLAEGERELRPQDIQARG
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
Sequence:
MVINKVEICGVNTSKLPVLKDKEMKKLLVRIRNGETECREEFIQGNLRLVLSVIKRFNNRGENVDDLFQVGCIGLIKAIDNFDLSQNVKFSTYAVPMIIGEIRRYLRDNNSIRVSRSLRDIAYKALQARDKLIKNNNKEPTVSQIAKELELPREEVVFALDAIQDPVSLFEPIYHDGGDAIFVMDQISDTKNIDENWIENISIKEAMKKLNDREKLILNLRFFDGRTQMEVADEIGISQAQVSRLEKTALKHMRKYV
The following text describes a protein:
Function:
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
Sequence:
MLRHCIPRLGIAKTVIKDNYSLSTLTNGLRVLTCDDGNGVTGMGLFMLNGAKFESPDNAGAAAVFEALPLRDNQIYTSREISQALSGLGNAFKVTNNKEALSVILMLPRYHQRDGLELLNAMCLHPTRNEEEFRIAKEKTHERTLLYDRDATSVCFELVHEAGWNGKGLGHSLNPKKEELDKLTLEKFTAFHSACTRPERTVLAATGVADHKSFAEEVEKLLRFNNADVAVQAMPQLQPGYYPYTGGSRLVHRTEAPESVNKFQEKSLSHVALFFQGVPINHPDYYNISVIQTLLGGGTSFSSGGPGKGMQTKLFREVLNREGFLHGLECITAWYSDGGLFGLYGTAPHQAVVSLLNVMIYQAASICQRVSPTHLEMAKNQLRSQLILLGEGREQLLSDMGFNLVVHNHIITATETMEGTRNITLDDLKRVCADMIKKPLTFTVYGDTTKMPSHESLEETVRKTYEKLN
The following text describes a protein:
Function:
Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane. May be involved in the regulation of intracellular pH, and the modulation of cardiac action potential.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Sequence:
MAHGSGRASAGGLPDPQVSLPVRPAGAGGGGGVGAGGAAGARTDGLSFWVVGSPQEELEEEVAGVAEEEEEEEEEEEEEDEDDDDDDEEDLGRSLAVRRFGDLIGKAPARDPNEPRRSFSERDFHVRRHASHHAHRPLSAHLPPAHKPPGLAPRRKRKKGRTSVTPSRETPAVREEGAGGPEAREDGRDEEGEPEGPPRRPKFSVGSDEEDVRRPPEPPRTPGRSPERKPEDPQSPPGSRPWAPRGGEKSRPWSPAAGYDLRGRLCPGSALDGAGSEDRRAPTDEAEARMLGSADLDDMKSHRLEDNPGVRRHLVKKPSRSPDPRRGSRGPAPTPSPPSETRKRKSRPDRRPHEVFVEMNELLLEKGQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAHGAALLDLEQTTLPGIAHVVVETMIISDQIRPEDRANVLRTLLLKHSHPNDDKDGFFPRNPSSSSVNSAPGNHHPGPGPDPRGPLAGEDPGDPASSRDLDAREKSLHLPGGDGHRGKCLKLLEKIPEDAEATVVLVGYVPFLEQPATAFVRLSEAVLLDSVLEVPVPVRFLFVLLGPPQAAVDYHQVGRSIATLMSDQLFHEAAYQADDRQDLLGAINEFLDCSVVLPPSELEGRHLLRSLAAFQRELLRNRRDRDRDRRAKPPRRTEAPAPGGGPAHGELWAVGGERPPEEEEQEQEEEEEDDPLRRTGSAFGGLIRDIRRRYPRYPSDLRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGIVFALLGAQPLLVVGFSGPLLVFEEAFFKFCEARGLEYLTGRVWVGLWLAVLVVALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFHKLYKVFAEHPLLPFYPPEAAAPPPWGPEGVAEVVNGSGEPPAGTAPPGGRPPARGPPAGPRSRPNTALLSLILMLGTFLIAFFLRKFRNSRFLGGKARRLIGDFGIPISILLMVLVDYSIPDTYTQKLTVPSGLSVTSPEKRSWLVPPLGSAHPFPPWMMVAAALPALLVLILIFMETQITALIVSQKGRRLQKGSGFHLDLLLIGTLGGVCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGLLIAGLVGLSMAMGAVLRRIPLAVLFGIFLYMGVTSLSGVRLAQRLLLLLVPAKHHPDRPYVTKVKTWRMHLFTGIQLSCIALLWAVKSTAASLAFPFLLLLTVPLRRCLLPRLFRQRELQALDSEEAEPNFDEDGRDEYNELHMPV
The following text describes a protein:
Function:
Self-assembles to form a helical, filamentous nucleocapsid. The capsid proteins wrap around the DNA and maintain it in an A-form by non-specific desolvation and specific coordination of the DNA phosphate groups by positively charged residues (Probable). This certainly protects the viral DNA under conditions such as the extreme desiccation of its host (Probable).
Subcellular Localization:
Virion.
Sequence:
MAKGHTSRSYSQRYAKWQAKFNAFSNPTVASTILSNVSPVAQQNFQTNVPKFTSVNENVSAVLTQYGITGPNRAIYQGFGLKVARALNRIGSGPALVNMINGLKGYYISAFNANPQVLDAVVNIITGSPTGYVS
The following text describes a protein:
Function:
Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes. The sterol transport mechanism is triggered by phosphorylation of FFAT motif that leads to membrane tethering between the endoplasmic reticulum and late endosomes. Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes.
Subcellular Localization:
Late endosome membrane; Multi-pass membrane protein. Note=Localizes to contact sites between the endoplasmic reticulum and late endosomes: associates with the endoplasmic reticulum membrane via interaction with VAPA and VAPB.
Domain:
The START domain mediates lipid-transfer between membranes. It contains a hydrophobic cavity able to accommodate one lipid molecule, thereby serving as a 'hydrophobic bridge' across the aqueous gap between donor and acceptor organelle membranes; The MENTAL domain anchors the protein in endosome membranes and exposes the START domain in the cytosol.
Sequence:
MPSAVDYSELGGSLPAIASLNASYSQASLSLPSPYYCPLPPGERKAFSDVRRTFCLFVTFDLLFITLLWIIELNISKSIWNSLENEVVHYNFKSSFFDIFLLAVFRFLCLQLGYAAFRLRHWWVIAITTLVTTAFLIAKVILSDLFSQNAFGYVLPITSFVVAWLETWFLDFKVLTQEAEDERVYLAAVNAACEPAPLICPRPVSDGQFYSPPESLAGSEDDLDEEGLGRRAVTEQEKAFVRQGREAMAVVEQILTQEENWKFEKTNELGDAVYTLEIPFHGKTFILKGLLQCTAELVYQEVILQPEKMVQWNRTVSVCQILQRVDDNTMVSYDVSAGAAGGVVSPRDFVNVRRVERRRDCYISAGMATNHNSKPHHSRYVRGENGPGGFVVLKSSSNPSVCTFIWVLNTDLKGRLPRYLIHQSLAATMFEFMSHLRQRINEVHVSYR
The following text describes a protein:
Function:
Required for endocytosis and endosomal pH regulation.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MENEEKREYLAKSRSNSRNFLNDSIESKNIFGVDKKSEPNLKQSIDGGLNFSTTSSYNPSNLPRTSVFVSARNLSSTVGHGKNEKKILTDLNFFLKPGSMVLLLGSPGCGKTSLMNTLALLTSNEKITGNLLFNGKTGDPNTHHRHVSYVVQDDFHMAPLTVRDTFKFSADCQSGDKSEKERIEIVDNVLDFLDLKHVQNTVVGDEFLRGISGGQKKRVTIGVELVKESNLLLMDEPTNGLDSSISLEMLTKIKNKVQQEKMSCLISLLQPGLEITKLFDYLMIMNQGQMSYFGPMNQAIGYFEGLGFKFPKHHNPAEFFQEIVDEPELYCGIDDGSSDGGSGDSGSSSGGSNYNYNFKNKASSTMMMMNNNNKIIPPLKGSDEFAMAYRKSIIYKHILEYIDSHIPDEEERSKFIDYSTTLKPYSTGFGRQLSLNVKRGFKLFLGNKASIRLRLLKNVIIGFILGTLYWKLDTTQADGSNRSGLLFFSLLTFVFGGFGSISVFFDQRQVFYSERAWKYYNTITYFLSMIVTDLPMSIVEVLIFSNFVYWMTGLNKTWDRFIYFFLTCLVCDVMSLSIIRSVCSFTKTKYAASAISPAVVSPFILMCGYMKHSNEIPGWWIWLYWISPIHYGFEGLLLNEHSGLDYHCSPDELMPPSFLPTFNTSYPVGFEGNQVCPITKGEQILDSIGFHTEFYYRWVDLAIISAFTLLFWLITLVCMKFLVFRVYRKDPVGIKKSKPNKTTTLIKMNRNSTDSTTTNNSMNYFNNKHNKKQNDDSDSGEEMESVDVDVKSSGKANLRKDIPIGCYMQWKDLVYEVDVKKDGKNQRLRLLNGINGYVKPGMLVALMGPSGAGKSTLLDVLANRKTGGHTKGQILINGQERTKYFTRTSAYVEQMDILTPVSTVREVILFSAKNRLPNSVPIQEKEEFVDNILETLNLLKIQHSLIGDVESGLSLSQRKRVNMGIELASDPQLLFLDEPTSGLDSSAALKVMNLIKKIASSGRSVICTIHQPSTTIFKKFDHLLLLKRGGETVYFGPTGTNSKIVLNYFAERGLICDPFKNPADFILDVTEDIIEIIQPPQTLPTSTSNENNNNNNNNNNNNNNNNNNNNNNNNNNNNGNTSDTLNNNNKKNLESSLSSSSISFDPVESFKESKENQKLLSIVENSIMPVGTPVAVYHGKYSSTIKTQFIELLKRSWKGGIRRVDTIRTRVGRSFVLGLVIGTLFLRLDKEQNDVFNRISFLFFSLMFGGMAGLSIIPTVSTERGVFYREQASGMYRVWIYYLTFVLSDLPFVIITSYAYVIPVYFLTGLSLSNHGWDFFYHSFISVMLYLNFGLTSIAFATSLPVEEMAFLLNGVLLSVTSLFAGFMIPPPSMPAAWKWAFYLDFISYPLKAFLITEFKDMEFVCTDNKGAIPIPIPSQNTTKFFCPITHGTQVLDRIDYKISFQYWDILIMASFTFALLVGGYLSLKFIRYQNK
The following text describes a protein:
Function:
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
Sequence:
MKKAVLLDVSAIMYRAYFANMNFRTKNEPTGAVYGFINTLLSIINEFKPDYMAAAFDVKRSSLKRTEIYSDYKSNRQSAPEDLIKQIPRIEEALEAFNINRYKIEGYEADDVLGSLAKKLAKQDIEVIIVTGDKDLSQLVEKNITVALLGKGTEGEKFGTLKTSDDVVNYLGVVPEKIPDLFGLIGDKSDGIPGVTKIGEKKALSIFSQYDSLEKIYENIDNLKSIDGIGPSLIKNLINEKDIAFMSRELAKIFTNLDITVEEDGLQYGMDREKLYSLCKVLEFKMFIKKLGLEEKPQNPTLFSIENLEEKKESPKIVEEENIEFTKEINLDLSNRELLIIDNENNLNEQKEYLTNYKKIASIYYEGLGIILSTEDKDFYFPLNHGGLLAKNIDRNLVVKFISELDIKFISYNFKALLNLGISFKSMYMDMMIAYHLISSQTKIDPIIPITEYSKLEPKDFKTAFGKVNVELITAQDFSKYLSDISIGILAIYDELNYLLKKEDLYKILMENEMPLIPVLSLMERKGIEIDVQYFKNYSLELEKELLKVEKAIYEEAGEEFNINSPKQLGDILFVKLNLPSGKKTKTGYSTDVMVLEDLESYGYNIARLLLDYRKLNKLKTTYVDTLPLLVDENSRIHTSFNQIGTATGRLSSSEPNLQNIPVKTDDGIKIREGFIAGEGKVLMSIDYSQVELRVLTSMSKDENLIEAYREEKDLHDLTARRIFNLPDSETVSREQRTIAKIINFSIIYGKTPFGLAKELKIPVKDASEYIKKYFEQYPRVTTFEKEVIEFGEEHGYVKTLFGRKRYISGIDSKNKTIKSQAERMAVNTVIQGTAAEVLKKVMVKVYDILKDKEDIALLLQVHDELIFEVEKNSVEKYSGILADIMKNTVQLEDVKLNININIGKNWAEAK
The following text describes a protein:
Function:
Probable component of the plant TOR kinase pathway that recruits substrates for TOR. Modulates plant cell growth and regulates the activity of ATPK1 kinase in response to osmotic stress.
Subcellular Localization:
Cytoplasm.
Sequence:
MALGDLMVSRFSQSSVSLVSNHRYDEDCVSSHDDGDSRRKDSEAKSSSSYGNGTTEGAATATSMAYLPQTIVLCELRHDASEASAPLGTSEIVLVPKWRLKERMKTGCVALVLCLNITVDPPDVIKISPCARIEAWIDPFSMAPPKALETIGKNLSTQYERWQPRARYKVQLDPTVDEVRKLCLTCRKYAKTERVLFHYNGHGVPKPTANGEIWVFNKSYTQYIPLPISELDSWLKTPSIYVFDCSAARMILNAFAELHDWGSSGSSGSSRDCILLAACDVHETLPQSVEFPADVFTSCLTTPIKMALKWFCRRSLLKEIIDESLIDRIPGRQNDRKTLLGELNWIFTAVTDTIAWNVLPHELFQRLFRQDLLVASLFRNFLLAERIMRSANCNPISHPMLPPTHQHHMWDAWDMAAEICLSQLPQLVLDPSTEFQPSPFFTEQLTAFEVWLDHGSEHKKPPEQLPIVLQVLLSQCHRFRALVLLGRFLDMGSWAVDLALSVGIFPYVLKLLQTTTNELRQILVFIWTKILALDKSCQIDLVKDGGHTYFIRFLDSSGAFPEQRAMAAFVLAVIVDGHRRGQEACLEANLIGVCLGHLEASRPSDPQPEPLFLQWLCLCLGKLWEDFMEAQIMGREANAFEKLAPLLSEPQPEVRAAAVFALGTLLDIGFDSNKSVVEDEFDDDEKIRAEDAIIKSLLDVVSDGSPLVRAEVAVALARFAFGHKQHLKLAAASYWKPQSSSLLTSLPSIAKFHDPGSATIVSLHMSPLTRASTDSQPVARESRISSSPLGSSGLMQGSPLSDDSSLHSDSGMMHDSVSNGAVHQPRLLDNAVYSQCVRAMFALAKDPSPRIASLGRRVLSIIGIEQVVAKPSKPTGRPGEAATTSHTPLAGLARSSSWFDMHAGNLPLSFRTPPVSPPRTNYLSGLRRVCSLEFRPHLLGSPDSGLADPLLGASGSERSLLPLSTIYGWSCGHFSKPLLGGADASQEIAAKREEKEKFALEHIAKCQHSSISKLNNNPIANWDTRFETGTKTALLHPFSPIVVAADENERIRVWNYEEATLLNGFDNHDFPDKGISKLCLINELDDSLLLVASCDGSVRIWKNYATKGKQKLVTGFSSIQGHKPGARDLNAVVDWQQQSGYLYASGETSTVTLWDLEKEQLVRSVPSESECGVTALSASQVHGGQLAAGFADGSLRLYDVRSPEPLVCATRPHQKVERVVGLSFQPGLDPAKVVSASQAGDIQFLDLRTTRDTYLTIDAHRGSLTALAVHRHAPIIASGSAKQLIKVFSLQGEQLGIIRYYPSFMAQKIGSVSCLTFHPYQVLLAAGAADSFVSIYTHDNSQAR
The following text describes a protein:
Function:
Dual substrate-specific glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase, catalyzing the first and committed reaction in the de novo synthesis of glycerophospholipids and triacylglycerols (TAGs). Can use both Gly-3-P and dihydroxyacetone phosphate with similar efficiencies and has a broad fatty acyl-CoA specificity profile. Transfers a fatty acid from fatty acyl-CoA to the sn-1 position of glycerol-3-phosphate to produce lysophosphatidic acid (LysoPA). These lipids not only are precursors of glycerolipids, but also are dynamic components of signal transduction systems that control cell physiology.
Miscellaneous:
MISCELLANEOUS: Present with 3100 molecules/cell in log phase SD medium.
Subcellular Localization:
Lipid droplet. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to both perinuclear and cortical endoplasmic reticulum.
Sequence:
MSAPAADHNAAKPIPHVPQASRRYKNSYNGFVYNIHTWLYDVSVFLFNILFTIFFREIKVRGAYNVPEVGVPTILVCAPHANQFIDPALVMSQTRLLKTSAGKSRSRMPCFVTAESSFKKRFISFFGHAMGGIPVPRIQDNLKPVDENLEIYAPDLKNHPEIIKGRSKNPQTTPVNFTKRFSAKSLLGLPDYLSNAQIKEIPDDETIILSSPFRTSKSKVVELLTNGTNFKYAEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHDRPSLLPIKAGVAIMALGAVAADPTMKVAVVPCGLHYFHRNKFRSRAVLEYGEPIVVDGKYGEMYKDSPRETVSKLLKKITNSLFSVTENAPDYDTLMVIQAARRLYQPVKVRLPLPAIVEINRRLLFGYSKFKDDPRIIHLKKLVYDYNRKLDSVGLKDHQVMQLKTTKLEALRCFVTLIVRLIKFSVFAILSLPGSILFTPIFIICRVYSEKKAKEGLKKSLVKIKGTDLLATWKLIVALILAPILYVTYSILLIILARKQHYCRIWVPSNNAFIQFVYFYALLVFTTYSSLKTGEIGVDLFKSLRPLFVSIVYPGKKIEEIQTTRKNLSLELTAVCNDLGPLVFPDYDKLATEIFSKRDGYDVSSDAESSISRMSVQSRSRSSSIHSIGSLASNALSRVNSRGSLTDIPIFSDAKQGQWKSEGETSEDEDEFDEKNPAIVQTARSSDLNKENSRNTNISSKIASLVRQKREHEKKE
The following text describes a protein:
Function:
Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAVTKARSSPRKPRVVITVSCSVGVAFPPSIDTRQVTTTTHIGLCAKSTKESDRSKPQAMAGEDPERWACDGTGALSLRLARGKVAADQLAPSEQHLISSFHPKFVYPLFGDEETIYGYEDLDIQLAFNSSTLKNYLAINYAAALPEPDPVEKIIYKFIPPDYTKSEATFNADLESSGTKKFIPPGKKISSYRTLPSKGKTKSEHFLTSKRWERCTDDQMEDEQDVIYELWAADWKSPGFREYHRRMQILVLFYIEGGSYIEEDDDRWEFVVLFERRKVKTADGDSSPYSYHFCGYVSLYSFYHYPSSIRLRLSQFIVLPPYQSNGHGSMLYSQIFQYLLTRPEVAELTLEDPSESFEDLRDREDLKLLFDNKVFDEKPLSELVPVPSEWYEKTRTKWKLANRQFARLLEMALRWKFTTLEESDNTKLERLYRIAVKERLYRFNYDSLVDLSKEERREKLQDTFQNVMDDYDRLLRGERRQID
The following text describes a protein:
Function:
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Subcellular Localization:
Nucleus.
Sequence:
GNDIYDARLNQTNIEDNSNDFYVIQLLESDGGGECMVYDRWGRVGVKGQDTIFGPYNLQDTAINEFEQKWQFTSYPKCYTWLERDYSANQTEESVVHEKPDSTINIQPQNTKLEPRVAKFLSLICNISMMKQVMMEIGYNANKLPLGTLSKSTILKGYDVLKRIADVIHLPDRRKLEQLSGEFYTVIPHDFGFQKMGDLVIDTPQKLKLKLEMVKALGEIEVATNLLEDDTQIQADPLYAYYQRLHCQLTPLAGADLASHHSKYFQFSKIGLILPVSIIILEQTFSIAKYLLNTHAKTHSSYSVDIVQIFRVEREGETERFKKLSNSKNRMLLWHGSRLTNWTGILSQGLRIAPPEAPATGYMFGKGVYFADMFSNSADYCNASPAATAGVLLLCEVALGDMSELLSANSDADKLPDGKLITKGVGQTAPDPLEAETLEDGGHLLYNEYIVYSVDQIRMRYVVQVNFKYK
The following text describes a protein:
Function:
Non essential disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May be involved in glycosylation, prolyl hydroxylation and triglyceride transfer. Able to fold proteins by being directly oxidized by ERO1.
Miscellaneous:
MISCELLANEOUS: Present with 1520 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum.
Sequence:
MKLHGFLFSVLSTCVVILPALAYSEAVTMVKSIEQYFDICNRNDSYTMIKYYTSWCQHCKTLAPVYEELGELYAKKANKDDTPINFLEVNCEFFGPTLCTDLPGFPIIELVKPRTKPLVLPKLDWSSMKFHERLWQRIKTWFNNPKYQLDTSRVVRFEGSRNLKSLSNFIDTVRSKDTEERFIEHIFDDSRNCNEELRSQQLLCKAGKEYYSDTLSKLYGDVNGLEKERRRLEALIKQNGDDLSKEVKEKLKIIRLQLSLLSHIEDQLEDTSSHDEL
The following text describes a protein:
Function:
Alternative, nonproton pumping NADH:quinone oxidoreductase that delivers electrons to the respiratory chain by oxidation of NADH and reduction of quinones. Ndh is probably the main NADH dehydrogenase of M.tuberculosis.
Subcellular Localization:
Cell inner membrane; Single-pass membrane protein.
Sequence:
MSPQQEPTAQPPRRHRVVIIGSGFGGLNAAKKLKRADVDIKLIARTTHHLFQPLLYQVATGIISEGEIAPPTRVVLRKQRNVQVLLGNVTHIDLAGQCVVSELLGHTYQTPYDSLIVAAGAGQSYFGNDHFAEFAPGMKSIDDALELRGRILSAFEQAERSSDPERRAKLLTFTVVGAGPTGVEMAGQIAELAEHTLKGAFRHIDSTKARVILLDAAPAVLPPMGAKLGQRAAARLQKLGVEIQLGAMVTDVDRNGITVKDSDGTVRRIESACKVWSAGVSASRLGRDLAEQSRVELDRAGRVQVLPDLSIPGYPNVFVVGDMAAVEGVPGVAQGAIQGAKYVASTIKAELAGANPAEREPFQYFDKGSMATVSRFSAVAKIGPVEFSGFIAWLIWLVLHLAYLIGFKTKITTLLSWTVTFLSTRRGQLTITDQQAFARTRLEQLAELAAEAQGSAASAKVAS
The following text describes a protein:
Function:
Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation. Required for NSL complex stability and for transcription of intraciliary transport genes in both ciliated and non-ciliated cells by regulating histone H4 acetylation at 'Lys-5'- and 'Lys-12' (H4K5ac and H4K12ac). This is necessary for cilium assembly in ciliated cells and for organization of the microtubule cytoskeleton in non-ciliated cells. Required within the NSL complex to maintain nuclear architecture stability by promoting KAT8-mediated acetylation of lamin LMNA.
Subcellular Localization:
Mitochondrion. Nucleus.
Sequence:
MSSFSPNQLRQCARFTGTPCTPDKEHQLREQIHSELVKIKYCANPTYECSLMRIEGYEYCIRHILRDPRSNFRQCSHVYSNGRKCINAVAKYDNKKELILTTLCFEHNRQTQLQKTHMNVGRIRSRVETNETLLHSLSSHINVEDIKPEVKKIERDDDEIDVVSPHVTPFVTQDHRNSIGHVVESSRKRRRILDYASDSSSNDADPPCLRNTAQDIEFYESDHESIDSEDDDPLKHAGVFTRAEAVKIAETKLIKLQGLYREQISYLQNVLRQRRRKYLHDIRRERELYCSIHDQLKDTPHERKLYEQLKALNSYHRRQGVEAVLYKKLKEKRARDALYAAKSSSNPKCVFTEGGVKCGERTLPCCKHCRKHILEDKRQVLFRACGVERSGVVCQEPVASILEDSSCVLHLTVAPAKRQYIQKVR
The following text describes a protein:
Function:
Required for the differentiation of the dorsal-ventral pattern, and does not appear to be involved in the process of segmentation.
Subcellular Localization:
Nucleus.
Sequence:
MFAIQSENYFVDNYSVSDLMMYPCVELNVEAAPTATTRSSEKSKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTERQVKIWFQNRRMKLKKSTNRKGAIGALTTSIPLSSQSSEDLQKDDQIVERLLRYANTNVETAPLRQVDHGVLEEGQITPPYQSYDYLHEFSPEPMALPQLPFNEFDANWASSWLGLEPTIPIAENVIEHNTQDQPMIQNFCWDSNSSSASSSDILDVDYDFIQNLLNF