lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly; Required for assembly of cytochrome c oxidase (complex IV).
Subcellular Localization:
Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MAAPGAGDPLDAKSGNAPFAQRIDPSREKLTPAQLQFMRQVQLAQWQKTLPQRRTRNIVTGLGIGALVLAIYGYTFYSVAQERFLDELEDEAKAARARALERERASGP
The following text describes a protein:
Function:
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
Sequence:
MTVGVLALQGDFREHCAVLRRIGVEPIEVRLPRQLEQVERLIIPGGESTTIGRLLTIYQMLEPIRARAGRDLAIWGTCAGAILLASVVTDQKQGGQPTLSLMNLTIQRNAYGSQLDSFEAPITMPIIGEKPLQGVFIRAPRIISVGSGCEAVGWLEDGSVVAARQGRLLATTFHPELTDDDRVHRLFLEL
The following text describes a protein:
Function:
Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. Part of the cryptic P4-like prophage CP4-57, it excises the prophage when overexpressed, which also requires integration host factor (encoded by ihfA and ihfB). Overexpression of AlpA leads to excision of the CP4-57 prophage, which inactivates ssrA (the gene upstream of the prophage) that encodes tmRNA which is required to rescue stalled ribosomes in a process known as trans-translation.
Sequence:
MARKTKPLTDTEIKAAKPKDADYQLYDGDGLTLLIKSSGSKLWQFRYYRPLTKQRTKQSFGAYPAVSLSDARKLRAESKVLLAKDIDPQEHQKEQVRNSQEAKTNTFLLVAERWWNVKKTSVTEDYADDIWRSLERDIFPAIGDISITEIKAHTLVKAVQPVQARGALETVRRLCQRINEVMIYAQNTGLIDAVPSVNIGKAFEKPQKKNMPSIRPDQLPQLMHTMRTASISMSTRCLFMWQLLTITRPAEAAEARWDEIDFNASEWKIPAARMKMNRDHTVPLSDGALAILEMMKPLSGGREFIFPSRIKPNQPMNSQTVNAALKRAGLGGVLVSHGLRSIASTALNEEGFPPDVIEAALAHVDKNEVRRAYNRSDYLEQRRPMMQWWADLVKAADSGSIVLTHLSKIRLVG
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MLDVNFFDELRIGLATAEDIRQWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDEEMRHNELSTLEAEMAVERKAVEDQRDGELEARAQKLEADLAELEAEGAKADARRKVRDGGEREMRQIRDRAQRELDRLEDIWSTFTKLAPKQLIVDENLYRELVDRYGEYFTGAMGAESIQKLIENFDIDAEAESLRDVIRNGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGRPLAMPRLDMVTGLYYLTTEVPGDTGEYQPASGDHPETGVYSSPAEAIMAADRGVLSVRAKIKVRLTQLRPPVEIEAELFGHSGWQPGDAWMAETTLGRVMFNELLPLGYPFVNKQMHKKVQAAIINDLAERYPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPRKKEILDHYEERADKVEKQFQRGALNHDERNEALVEIWKEATDEVGQALREHYPDDNPIITIVDSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPVKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCQTERGIVVELAERAPDGTLIRDPYIETSAYARTLGTDAVDEAGNVIVERGQDLGDPEIDALLAAGITQVKVRSVLTCATSTGVCATCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGEDITGGLPRVQELFEARVPRGKAPIADVTGRVRLEDGERFYKITIVPDDGGEEVVYDKISKRQRLRVFKHEDGSERVLSDGDHVEVGQQLMEGSADPHEVLRVQGPREVQIHLVREVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLIDRAEFEAENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGINRYRNIAVQPTEEARAAAYTIPSYEDQYYSPDFGAATGAAVPLDDYGYSDYR
The following text describes a protein:
Function:
May be involved in the modulation of rDNA transcription.
Sequence:
MASQLSNHYRIYIKNLSYSTSEKDLEELFGKFEPYTIHFSRSGRHRPLGIAYAEFKTPEQIESVIKEFDGHVLKNRKIAVKKHMAYDPNNRRFSFKRKSSIKNGKRNQTGTLSSEMPVLVAKESLLHDDETVSIKQPKKTHSGKKELSMDTIMIQRVYGKVTDESLRDFFKEYNPSQIYIFKSRKPKLNPMNFTGSHVSVLAKLDASKIKLEDIIFNLKSRKLNGKHINMKPAYKSKVLEVEKAIAQSKSLENTEGCGDTSCNDSVVANEKTSIANKDGKNNDGENSAISLIGTVSNC
The following text describes a protein:
Function:
Putative transcription factor with an activatory role.
Subcellular Localization:
Nucleus.
Sequence:
MDKEKSPAPPCGGLPPPSPSGRCSAFSEAGPIGHGSDANRMSHDISRMLDNPPKKIGHRRAHSEILTLPDDLSFDSDLGVVGNAADGASFSDETEEDLLSMYLDMDKFNSSATSSAQVGEPSGTAWKNETMMQTGTGSTSNPQNTVNSLGERPRIRHQHSQSMDGSMNINEMLMSGNEDDSAIDAKKSMSATKLAELALIDPKRAKRIWANRQSAARSKERKTRYIFELERKVQTLQTEATTLSAQLTLLQRDTNGLTVENNELKLRLQTMEQQVHLQDELNEALKEEIQHLKVLTGQVAPSALNYGSFGSNQQQFYSNNQSMQTILAAKQFQQLQIHSQKQQQQQQQQQQQHQQQQQQQQQYQFQQQQMQQLMQQRLQQQEQQNGVRLKPSQAQKEN
The following text describes a protein:
Function:
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MLGAVLTARGGAESMRCGPACRNDDELEGCKLQRQLCRCMKVAMSSPEAIRNEMKHCSPARQGGRSRRAVAKIKATAAWRYPPSDWTLHASALSFQLGSLTPLLGGRRALTATTVEKRPSTDGLVDNIDPRESHELEELPYVEKPATTEQPPLPLKEKLITCFWIALNTLSTLGLIFLSKKVFSDAQIKKCQLMVVMWHFTATGLVLFISTLGPFRAFKAVRLNWLHMLPVCGFFAGYVVLGNLSLTFNSIGFYQLSKVMTTPTVVLINFVMFRKQVTRYMLAAIIATCIGVSFTINETAKTQLFGVIVATMAFCSTALYQIWIGKKIEDFAVSPPQLLLNQAPISVCLLIPFVPFFDTIPNLSEVPSTILWSACASGIMASMYNLSQFLIIGRTSALTFNIVSHLKTILILSIGWYSEGKILSPREWFGVLLALGGGWVYSHLALKAKKQGGK
The following text describes a protein:
Function:
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
Subcellular Localization:
Membrane.
Sequence:
MGAKCLFYSQDLFLYHHGTLMGGPLRFYQLVFVSILCAACYSSLPEKIPREPPDNLQMTSNNFQHILSWRAHSDPTVPTYYRVLYSSHSNWKIAKQCSRIVQPFCNLTDDFQVVSDEYSAFVQSFVGTEVFNSSLLYFSPLSETFLGPPEFNLSSCVHCINITIKLPPTHLRKNGKLLSLFDIYNKVDYEITLRTVGEEHKRSPEKVTEEPFSIVIEELYPNRNYCVSVMVTASLNKHSIPSAWKCITTDSVAEKDYYGITIAGAICFSIILVVILKCLHLGGYILHKKSLPDTLIFTKMFSYLPFTFECEEITSVEIIYKEVKKKAEGSVGAVSSEDDSDDSESDAMSNHDYTRRDIVRRAPQSSDTSPVFVQHSTSSTCDGSSSWVSQNPDDGPEVFEENEMDAEEEKDTDSELLSPLSKVNCTYSLRSRSNFCFTINLKSVLLGISEETTDSSAALLSSQEDAVDWQCAHAVESKLLDDTESTQKPHHLNNSDVWQNSSGSSSESDSSDSDMDPKSEYVRR
The following text describes a protein:
Function:
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
Sequence:
MRACSLQQRRAAAPASGARCFVPSVRPPVGVRPVRSLLHPTQQASVQHASALVAQAVASQAGTPPPRAGKKKVKKMVDITGEVLKDLSNGMFQVKLENGVSVIAHLSGKIRQNRIKVVVGDKVTVELSPYDLTKGRITLRHKPGQDPTASASSSGSGSGAP
The following text describes a protein:
Function:
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MKIRLRITWEIILLILIVLVFLVSSFFSPYFLDIVNLLDNTTNFMEKGLISLAMTYIIISGNIDISVASNMGMTSAFMGVLHRMGTNIWICALVGLIIATLGGYLNGYLIVRFRLPAIAVTLGTYALYRGIAYILLQDTAVGIESESFMYLGQGYIAGTPVPFSLVLYVIFAIIFGFVLHKTTFGRYVYSIGNNEQACKFSGIPVEKIKIVLFTIAGFMSGLGAILLTSRLSSIRPDIGSGLELEVIATVVLGGVSILGGSGNMIGVVLSLFLIGFLTYSLNLLNIPSQVITIIMGSLLVGTVVISNLLEQRRARAVK
The following text describes a protein:
Function:
Part of the accessory SecA2/SecY2 system specifically required to export SraP, a serine-rich repeat cell wall protein encoded upstream in the same operon.
Subcellular Localization:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Sequence:
MKHKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVDYEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQVPTDKAIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYSLDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENQDFKALAKDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAVVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP
The following text describes a protein:
Function:
May be an RNA-binding protein involved in control of an RNA processing pathway that influences the regulation of cell growth in early log phase. Can bind to RNA and single-stranded DNA but not double-stranded DNA.
Miscellaneous:
MISCELLANEOUS: Present with 1540 molecules/cell in log phase SD medium.
Sequence:
MMSNVANASQRQENPYIIPLPPSSTVETSTEPPRTLWMGDLDPSFDEATIEEIWSKLDKKVIVKLIRAKKNLLIPCSSTSSSNNNTSEENAENQQSASNSTDQLDNSQMININGISFIDPSTTQLHHAGYCFVEFETQKDAKFALSLNATPLPNFYSPTTNSQTNPTFKRTFRLNWASGATLQSSIPSTPEFSLFVGDLSPTATEADLLSLFQTRFKSVKTVRVMTDPLTGSSRCFGFVRFGDEDERRRALIEMSGKWFQGRALRVAYATPRNNMMLQLQEQQQQQQQLQQQHQQLDQEDNNGPLLIKTANNLIQNNSNMLPLNALHNAPPMHLNEGGISNMRVNDSLPSNTYNTDPTNTTVFVGGLVPKTTEFQLRSLFKPFGPILNVRIPNGKNCGFVKFEKRIDAEASIQGLQGFIVGGSPIRLSWGRPSSSNAKTNSTIMGASQYMSSNGLRAPSAASSVDNSKQILEQYAEDKRRLFLHQQQQQQQQQQQDGNFSMEQMAHNNYYNYNNYDYHRNKNGSHSDLVNLQRSNVPYMQEDGALYPHQYSSPSYSLHPTGNQFSNATNNLPQFGNAMSISMQLPNGNSNKTASSMNTNPNTNMIMNSNMNMNMNVNPVPYGMGNGANMYDVSRMMTPPLNIAPNSNNSKSSIMNKHPNRNNVPPIHPSLLH
The following text describes a protein:
Function:
Transcription factor (By similarity). Involved in positively modulating longevity and stress tolerance, probably acting by positively regulating expression of transsulfuration enzyme cth-2, leading to increased hydrogen sulfide production and therefore increased protein persulfidation, a protective modification of redox-reactive cysteines. May mediate longevity and increased stress resistance induced by mTORC1 suppression.
Subcellular Localization:
Nucleus.
Sequence:
MAYVNEQNPQFLLYNGMHNQTHSTPQYHNHHHHHHQSPTYPQSYFNPYSHQSYQQHHLNSDVNFQMVPQSTSVPPDPFCSIEPMETNVQAKEQILEEIVRECEEIERRSNSSASPASNWSSDEHDSQSEKSYHPYKTPEKKERKKAQNRLAATRYREKKRREKEEAMTCIEGLSVTNGKLKDQVSELEREIRYFKKFMTEMGMKTVTD
The following text describes a protein:
Function:
Prenyltransferase; part of the gene cluster that mediates the biosynthesis of neosartoricin, a prenylated anthracenone that exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent. The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone. The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation. The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5. The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2. There is no gene encoding O-acetyltransferase in the nsc gene cluster; thus, the last step of 2-O-acetylation leading to neosartoricin may be catalyzed by an unidentified O-acetyltransferase.
Sequence:
MSLQLNGKSRGTSPGNAQPLPIFDALCRSLPVGTADEQFWWKLTGRHLARMMLEAGYPEHRQVECLVFHRFKVVPTFGPQPRSAEPWYRSRVAASAGDGAPISYSWRFGTADRKPYIRNYIEPLGPLTGTAADPNNDVATRAFLQDLTTTLPNLDLSLFWTFEPHLVSRFSDKADREKYAGPSVLTGVELSPDSDAIDIKMYLYPRNPEQISQLLSTIIPKAMRDAYGEDVCLDSLNIVKDFLTNHPDGRQLKPRGTTGIDCCKVQDSRVKFYVATDNTSFDHIATVMTIGGRRPLSTEVLDKLRELWYELNGLPSDFPTSEQVPTGQGQELPAGHHGVGFYYDIQPRLALPDVKAFINVRKHAKSDLAAAETVISFLERHGQGHHNPRAYLNVLRDIVPAEELETRVGAQAFYSVAVKKEELDITAYFIPQVYRRFASVQVELNGQRRSRFE
The following text describes a protein:
Function:
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSDSIARRSGNNKRRNIYKSRSSYVDESLFDSANKSVSFHEVKFDPPWIKNNSNRELAANSLAWNKGKAGNDKKSDRERVRPDSRNLKRPYRKQVFKSSFTDDSLFGDPLIAQEQSMRELPPWGKKEKGKYMKPLLWDPDPSNIRIEGSRSSRDARRPDSVSGSFSYSRSSTRTATYGVSSARRPQSATVRPPWR
The following text describes a protein:
Function:
[CLE40p]: Extracellular signal peptide secreted by differentiated root cells that regulates root cell fate. Acts with ACR4 as a ligand-receptor pair in a signal transduction pathway, coordinating movement of the root tip and organization of cell divisions in the root meristem. Promotes cell differentiation in the distal root meristem in a dose-dependent manner, especially the transition from columella stem cells (CSC) daughters into columella cells (CCs). Induces ACR4 expression in root quiescent center (QC). Involved in WUX5 QC-specific expression pattern regulation. Regulates the transition of protophloem cells from proliferation to differentiation, thus impinging on postembryonic growth capacity of the root meristem; this signaling pathway requires CRN and CLV2.
Subcellular Localization:
[CLE40p]: Secreted, extracellular space.
Sequence:
MAAMKYKGSVFIILVILLLSSSLLAHSSSTKSFFWLGETQDTKAMKKEKKIDGGTANEVEERQVPTGSDPLHHKHIPFTP
The following text describes a protein:
Function:
Possible cargo protein of a type 1 encapsulin nanocompartment involved in protection against oxidative stress (Probable). Iron-storage protein that displays ferroxidase activity, catalyzing the oxidation of Fe(2+) ions into Fe(3+) ions, that can then be deposited as a ferric-oxide mineral core within the central cavity of the protein complex. Retains ferroxidase activity inside the encapsulin nanocompartment with a slight decrease in rate. It is not known if this protein is normally found in the encapsulin nanocompartment.
Subcellular Localization:
Encapsulin nanocompartment. Note=Forms an approximately 12 nm shell inside the encapsulin nanocompartment, suggesting the latter encapsulates the entire 24-subunit homooligomer.
Domain:
The C-terminus (residues 163-181) targets the protein to the encapsulin nanocompartment. Interestingly the C-terminus is localized iside the ferritin cage, in theory it does not touch the interior of the nanocompartment.
Sequence:
MTEYEGPKTKFHALMQEQIHNEFTAAQQYVAIAVYFDSEDLPQLAKHFYSQAVEERNHAMMLVQHLLDRDLRVEIPGVDTVRNQFDRPREALALALDQERTVTDQVGRLTAVARDEGDFLGEQFMQWFLQEQIEEVALMATLVRVADRAGANLFELENFVAREVDVAPAASGAPHAAGGRL
The following text describes a protein:
Function:
Translation activation factor that as part of the MRH5C complex specifically recruits cox1 mRNA to the mitochondrial ribosome for translation initiation.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MVKGSLLNRNINALNCRCLAQKLTSWGLLNIRSIHADSNRGVVNSSNLIIIPPYKPKSKSVLRSPYLTSHYVDALAFKLVEDPTVHNTLEDVFQDIESYKPKSVNTSAKSFRQLVNTLEVAFRKEQLRKFAKVFHIKSSSLRKKEIIERILLDHWKLRIHGDAMDDMLAIKDVTLCPLEMFFLLLNNASALRDISQKHAAHVVINVTNNNIKIEAKKRDVAIVEELISGIFKHLKSKTIDVTEYYANIINKNAVLLSERCKAYIELSGKAQIKITTAFGNCSFDEIERKLLSFVMLFENTDKCLIDSECLTSKKSFTLNDFTYDFRLPWYLKDDSWKRWCRVKEYSWNTSVLSDEALTRNSLTLPVPIKPSINKDISSIEVKDLSQKNTTQSKKLNSYIRDSFHSVNDFWFSSHATNTEQCFTKRLTATFGYSLFSSSFLSHTKNPDVASFYVKERSKAHHFLFNTFVDQIPSYLKNHSILDETTRKSFYRIILSSNSLSTSLTYPLIEIILPIKNGFLMGKETFQIAFKKSRGYQILLPESELDLKINTTTFKTIANNKSVDAFLDDCVSFFSRPEMTQDSQLNASSGFLTNFSLKDSTDRFYKVLSYEKVSERFVKIDDSYITYSDIFSPLSHSHKDWFRIHTEENSSKNFYEIISEIVGGFPYYSQANERSLIS
The following text describes a protein:
Function:
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Sequence:
MAAMDLNAEREKIRKEIEELERSLDPNTATIEVVVSESSLDSDSGDSLEDDGLDTHISAEEKQSGEASSEDDDDDDKDKNLPEDPETCLQMNLVYQEVIQEKIEEVEVLLTQNKEQQEEVMWALAGSKTAKTKEGKSLPSNIFVGHFMKPYFKDKATGIGPPANEETREKVAQGIKSFEELLVTKWKTREKTLLRNSVMSDRLQRLLQPKLLKLEYLNRKLEKIMNKMDRQIVEKQIAETEKEIEDINQLPSERLLGDRMDEHDWEKISNINFEGTRNAVELRKFWQNHEHPSINKAEWGEKEIEKLKEVAAKHSYLNWQKIAEELGTNRSPFQCLQKYQTYNKDFKRKEWTKEEDQMLTQLVGEMRVGSHIPYKKIAYYMEGRDSMQLIYRWTKSLDPNLKKGFWTPEEDAKLLRAVAKYGERDWFKIREEVPGRSDVQCRDRYLKRLHVNLKKGKWSPSEEEKLIELVEKHGVGHWTKIAAELPQRTGSQCLSKWKIMIGDKKKQRNRKRQRKSRRGPRGGQHVPSSSEESEIEFTDNSEEEEEKKSDQEKEPAVPSYTVPNIDLWIPSGEPRATPRGAVTIQTPRPRARTMGSGSGGATPGPTGDAGEGQPRGQGASMDVSATPKGFPCARSTDIPLENPEPQGNPEPLENPEPLEKEDPGSGKQVLKLTPDEVKKVLRSNTYILRRKLQEKLKKPRLPTSSVMPQVSAGMSGDQVLQVWENTVEKRLQRLKVGLRRNIRRSNLDRRLLLAVTPWVGNVTLPRFQNSRKGLVLQTKVKKRPLQTVLLTSTPMFTLFIQLFQIDADGCMKVIQERKANQVEVVQVEPGNPEQLRQVGRDGQATPDLRNGSYLPRGGVGTITEASCSSQDTSGCQPQKDPAKGNSRRRSAPRVEDGQLARDGKVTAQAGAPSAPQPQRPKPKTVSQLLREKRLRESKATMPNPVILAPQVLVSQPVLLRHPLQPVIPSGPATATLAQAGPPVKPPAPSPTSTPISSASLRALASGTLAVASENSSGQVSSEASRAVGVTEDPKAKEEGKSSAPLTVVIPPPGDGRGRVQDGGSPQPGVPPNPSPGPGQLLAISAPGGFTLARGAPSGGKQGPPEASPLLPPAPVRFQQPRLLPALAVRPSGPQGGPSEILPFTWVVTPQGLVPMSVQAFVGLHGPSKTVGDLGAANCQGPVGTTLVPPGGPTLRLLLPPATTPLAVTSSGAPGTNTAVAPGSSLSSHRVAGEPAPPTVELSHSASLPSAAPPDREVSRSPEEVSAAEKSQPPQPTPSPQSQNPNGGQRAEPLGSHGLPASATKSPSSGEGEAPSSQSHMPKDLPATQVGRCPDRTGASGNSAPTTAPLPARVGKDRPIAPRPEATPSPGGHPAPADPPPRGHPPPGGDRPPGPVAPDKNKLDLTLISLEEEAVVREWMKGKRGVHVPPLKNNLPYLPPSVYNLKTLSGLLREKKNLERSAASLVAGDGGPAGSELSPEGLEAIRALVRERLKDNPAYLLLKARFLAAFTLPAFLATLPPPGVPTTLSRRPEESEEEDEDDGEEEEKDLTDEESGEEDHPPGEAQPGPEAATSGQVQCRVGAVGQGWEKWVELGTLGRPCGKPKESQRAPEPLPWGPAGTNRQAGLSQRRTGIHISPTPRGANSH
The following text describes a protein:
Function:
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
Subcellular Localization:
Secreted.
Domain:
Proteolytic cleavage leads to an important conformation change. This reduces the affinity for steroids (By similarity).
Sequence:
MLLTLYACLLWLSTSGLWTSQAKDPDSDLSTRSRHRNLAPNNVDFAFALYKHLVASAPGKDVFLSPVSISTALAMLSLGASGYTREQLLQGLGFNLTETPEAEIHQDFQHLHSLLKGSNITSEMTMGNALFLDRSLELLESFSTGSKHYYGLEALAADFQDWAGASRQINEYIKNKTQGKIVDLFLEQDSSAMLILINYIFFKGTWTHSFPPESTREENFYVNETATVKVPMMFQSRAMKYLNDSLLPCQLVQLEYTGNETAFFILPVKGEMDTVIAGLSRDTIQRWSKSLIPSQVDLYVPKVSISGAYDLGSILGDMGIVDLLSHPTHFSGITQNALPKMSKVVHKAVLQFDEKGMEAAAPTTRGRSLHAAPKPVTVHFNRPFIVMVFDHFTWSSLFLGKIVNLT
The following text describes a protein:
Function:
Plays a role in neuronal and neurobehavioral development. Required for normal expression of the postmitotic and mature neuron markers elavl3 and eno2 and neurobehaviors related to circadian rhythm and altered light-dark conditions.
Sequence:
MAYSGAQKALKSDKLDEAQALAKSCAGRPDFLPCDGLSICATHSHGKCFKLHWCCYLGWCHCKYVYQPMTNVAQLPSTPVPAAPSDCPDTIDLSISLTERFLRISPCFQAPPCPESPKYCNIAELFIDDYIVKRINGKMCYVQRPQAHVEPAQMNPIQKQHTEDKQIVEETVKGPKMGHCSSPSTSEDSGINALGGHFLESCEEESEEEDELSTDGHSSPGSLWDQDECTLLSPSKSMVEIIENIETTV
The following text describes a protein:
Function:
May play a role in breast tumorigenesis by promoting estrogen-dependent cell proliferation, cell-cell interactions and migration.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Note=Prominently localized to cell-cell borders.
Sequence:
MRWAAATLRGKARPRGRAGVTTPAPGNRTGTCAKLRLPPQATFQVLRGNGASVGTVLMFRCPSNHQMVGSGLLTCTWKGSIAEWSSGSPVCKLVPPHETFGFKVAVIASIVSCAIILLMSMAFLTCCLLKCVKKSKRRRSNRSAQLWSQLKDEDLETVQAAYLGLKHFNKPVSGPSQAHDNHSFTTDHGESTSKLASVTRSVDKDPGIPRALSLSGSSSSPQAQVMVHMANPRQPLPASGLATGMPQQPAAYALG
The following text describes a protein:
Function:
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
Subcellular Localization:
Nucleus.
Sequence:
MTQSSSCRPFSLPALHEYRFELDPGESITIKLVSGTAEISGFELTSGQEYTFGDEIRSAIFSWHGADLEISRKASTEYVAEESTVPAYMALHLALERARLGSVAPKHFVPHVEPPPRLQVSSDAQEPDEEKHGPHVMVIGSLASGKSTLIKTLANWAVKSGRTKVEGPGLLLVNLNPNDGGWTVPGTFSVAPLNVSIPTTTPVLPFGSTPTTGPAPSTPNPALFAPSLNALSFFYGHTQFSRNTGLAEVLIKRVGSALETRIEKSGETALWRGGLLIDTPAEFSEKAKGGLVKSVVRALGVNILVVIGNEKLHLEISKLMSINKTVQVVRVPKNGGATDLDITYRRRLESNQIRSYFYGGPALSQGQLSPFTIVVKFEDLTIYRIGDEAIVPSSALPIGATRSVKPTTLTKVDPENGRSMSNILNLVLSIPQAEWDGLDPESDAAFEACSGPSLGFIHL
The following text describes a protein:
Function:
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins. Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress.
Sequence:
MLSGRLVPGLVSMAGRVCLSRGSAGSGAIGPVEAAIRTKLEQALSPEVLELRNESSGHAVPPGSETHFRVAVVSSRFEGLSPLQRHRLVHAALAEELAGPVHALAIQARTPAQWRENSQLDTSPPCLGGNKKALGTP
The following text describes a protein:
Function:
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. Required for the transport via the ALP pathway, which directs the transport of the cargo proteins PHO8 and VAM3 to the vacuole.
Miscellaneous:
MISCELLANEOUS: Present with 3570 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Sequence:
MVDSIHRIASALDTAKVITREAAAVATSKLGESSYTYYSQNINPQQLVTLLNSRNSREVRDAMKRIISIMASDDDSIDVQLYFADVVKNITTNDTKVKRLIHLYLLRFAENDPNLTLLSINSLQKSLSDSNSELRCFALSALSDMKMSSLAPIILHTVKKLVTDPSAMVRGEVALAIIKLYRAGKNDYHEELLDILKELMADTDPKVISCAVLAYKECYADHLELLHGHFRRYCRIIKQLDSWSQSYLIELLIKYCKQYLPKPTVVDKSSEGSPRSCPLPDKYNEIEYPSYEVVNDPDLDLFLQSLNCLIYSSNPTVILSCCNALYQLASPLQMKNTKFIEALVRTVTMTENQGNKEMLLQAIHFLSILDQTLFLPYTKKFYVFPKDPIVASIWKIQILSTLINESNVKEIFKELKYYVASAHFPENVVIMAVKSLSRCGQLSTSWESHVMKWLIDHMESHNLSASVLDAYVNVIRMLVQKNPTKHLRIIFKLADLLTVQTSLADNARAGIVWLFGEIASIEFKICPDVLRRLIQNFSNEGPETRCQILVLSAKLLSYDIDNFKQAQVTGSEENNQNPPYYDFSGSRISQMYNAVLYLAKYDDEFDIRDRARMISSLFDSGKYEIVSLLLQAPKPTARSDDFIVSARLETHTPEIKEFFRMLPWNTEITEVGETGNDIREGAELKDYNKYKKSFSSQSFITNNSARSFTSSSNAKLTGINDGDSNSISGKGNVNTFTSQNGKKYRLQSLDEFFSDIPERKSKPRKIIKVVEESSDEDEDESEESSDDDEYSDSSLGTSSSGTSSSHLEL
The following text describes a protein:
Function:
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
Subcellular Localization:
Cytoplasm.
Sequence:
MKGTIIKGIGGFYYIKIDNSEEIIECKARGKFRHTELTPMIGDYVEISIDKNNKGAIEKIYERRSELFRPAVANVTQALVVFSFKNPDINIDLLNKFLLLCEYNNLKAIVCFNKMDLVNKEDYKDIISMIEQAGYDIIFLNAKEERNMDIIKKLIKDNVTVFCGPSGVGKSTMLNKIIGKETMITGNISEKLKRGKHTTRHSELIYVDEGLLVDTPGFSSLDINFMEKEDLLHCIPEFRDFIGECKFTGCLHHREPNCAVKKAVEEGHIHKDRYNFYIKTLEEFMNRRKKKW
The following text describes a protein:
Function:
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MASKSWLNFLTFLCGSAIGFILFSQLLSILLGEEGDTQTNVLHNDPHARHSDDNGQNHLEGQMNFNADSSQRKDENIDIQVKILCWVMTGSQNLEKKANHVKATWAQRCLKVFFMSSEENKDFPAVGLKTKEGRDELYWKTIKPFQYVHEHHLEDADCFLKADDDTYFILDNLRWLLSKYDSKEPIYFRRRFKPFVKQGCMSGGAGYLLSKEMSRSSSTEDLALGRCMEIINVEAGDSRDPTGKETFHPFVSEHHLIKGPGCCSDLAVSFHYVDFTTVYVLEYLVYHLHPYGYLYRYQATLPENILKEISQANKNEGTKVKSGNP