lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
Subcellular Localization:
Nucleus.
Sequence:
MPDILNQAPATPSSALYATHILHLPKDRIYIHRYALSSAPGASTKDVVEDKMAKFWRDIADRAGNGKRLLEGPVATIVGQIERELWCFACKEDGISPPDGINEIQPPLPPLVPLELLSCPDHSSSYNCLSESSCDVTLNLEGETRKAWELLANALIETFAWKGGRRIILRDSGVVPFTPPFKPSLYPFTSGSLLLSLLPSRSPTSLLPPYPIPTHTLIPLSLPSILITTVLTPTPAQIARLNQTFDTLLGPGWKTGREQRVVREFVFGFGAETGTVSEMQEKGGEEEGWGVFWVPLLKKTSESGDKGVLTVWPIHLALPLPSDSFSHNPSATATPPSTQLKQSGRTEEGEQGLMQTAYSLFDFLASYREPSVPPEGDGGQLDDQDPDYDNELSLGDTDADMNETDGEGLNLQETGMGAGGDIEMEPTPKGGSDIDDLFSSSSPTPTPNMNVSSQPHSNKSPPPQQAQDGSNNAQDGEEDFMNSLVSVRDPSPPAQSQVMGIGDRGREKEVEVEITEDDFAFFDSPAAEEGDGIGMDVDMSIDSGINQSVPDGAIDHGGEIGAEPSIGQEKGLLAEEMVKTASPKITEEAGQDELTLVPLVGNGMEVDGIPPEPLPLPSVETAAKELQPPQLPIPPQPSSSPPILETSPKTPEQLASQSPHLTSPSIPLVPAAAPSNPLIPISFQPLPLLPPSHSSSSYPYCSTYGFAPPSPASTPESSLLARLTSYQTQYHSRPGSDAPSASQGQGATRRLSSKPKSTYADAWFSLSGGDDDGDGEDGDEDDMDSQTYTCPPTPMSQMEEMTTEIGSDAGSSDVDGVTGTDIDSGATGLMGVKDDDGEIKEDDGEIEWKGTKCIGSEWVILRDHPRLVQPKGEAENEIGWKVESVWDEAWGTLPSAVSGKKDSTKAKENLKEKKVKDVNWTKVVQEIIGNRAFRKSVLDPEDEYEQSSAWMGSLLEGDALCEVFGSDVLPVNLPQPQVNATSPSTAHIIRLSIAALSYWSQLGLEPQGGKKDVKMFIICKDSDEALGKMLGEGVKLGWEEERYGKAEFSGVVKGKMEDFGELAIGITEQSTGSVNTIVYLLTPPSQIPLNIYSSLIPNSPNTLLIPVPTPSNPSTSFVHEQYLTLVRTAYDRLPTFLRPIYVRGEPLRVSEEDAWIQCPAWVLARKEAVKPEFVMTWPVDEYDVLNRWRMWHVCYDVVSSTSLGPGALVVWVGDDRGETGHVRVFEDVGGWKEGMEKTCAYGREIAGRWNLEWRLSVCRAGIMAKEELQAWKDILKGKTWPITLLTSEAPSPLNPSYQKTPPKVRAIANIGPSILSDSSTRIIDTALSAQLTVLPLPLPLELSSDKGSPQIIYPRRTFLLTTPALDVSQHYTTKYHILSHQTPDGRKDQEDGGIVAEIAEEYHRLGCLARERWEGQGWLDSVRWGRALLEKR
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'.
Subcellular Localization:
Nucleus.
Sequence:
MRPASSGWRSSPTERQQRAAGTRLGRARHPSRLHPTPPLVHEFTSRGHQAGFTTGQQKHVIRSRTPYLGAYVGGNQVHVPVISIIHHKLCKGAIDAQTTASHKSSTHIKKQMSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAAGASTAPAEPRYSQPATSTHSPPPDPLPCSAVAPSPGSDSHHGGKNSLGNSSGASANAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
The following text describes a protein:
Function:
Involved in trophoblast cell proliferation and differentiation probably by affecting mitotic cell cycle progression. Proteolytic activity and nuclear localization are essential for its role in cell cycle progression (By similarity).
Subcellular Localization:
Endosome. Lysosome. Cytoplasm, perinuclear region. Golgi apparatus. Nucleus. Secreted, extracellular space.
Sequence:
MTVAVFLAILCLRAALAAPRPDYSLDAEWEEWKRNNAKTYSPEEEKQRRAVWEENVKMIKWHTMQNGLWMNNFTIEMNEFGDMTGEEMRMMTDSSALTLRNGKHIQKRNVKIPKTLDWRDTGCVAPVRSQGGCGACWAFSVAASIESQLFKKTGKLIPLSVQNLIDCTVTYGNNDCSGGKPYTAFQYVKNNGGLEAEATYPYEAKLRHCRYRPERSVVKIARFFVVPRNEEALMQALVTYGPIAVAIDGSHASFKRYRGGIYHEPKCRRDTLDHGLLLVGYGYEGHESENRKYWLLKNSHGEQWGERGYMKLPRDQNNYCGIASYAMYPLL
The following text describes a protein:
Function:
Extracellular metalloprotease that contributes to pathogenicity.
Sequence:
MKLISSVLVGMLTFASFVVSTPIYTVVSYDGYKIYKVKIESDYEAGLIREILEDIQLGVKSWNKVAIGSEAHLQVAPSSQDRFISKLEGVPHSIMIENLQQNIDVEYARTRQNSERLSSLFARDGNLALTAKEIFTDYQDQSVLVAFIASLPGVTQFSLGKTYEGRDITGFTFGTGSKNIVFNGGIHAREWIAPAAATYITHYLTGGSADAVALLKTYTFTVIPVLNPDGYAYSRSTDRMWRKNREPNKNPNCVGTDPNRNFPFKWGFEKDSFDECSETYRGSSAGSTAEAKALIGYMKKVKNVASYIDIHSFGNMLLFPYGYTCANVPEPDYSNLVKASKVATDALYAVHGEKFVSGPACSTIYPTNGDTTDYTYSLGITYSFTFELRGGGHEGFDLPAEEIVPSSEEATAALVALWKSIS
The following text describes a protein:
Function:
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. Required for the formation of chemosensory cilia that detect chemosensory cues.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium axoneme. Note=Moves along the axoneme.
Sequence:
MEEEHEEESHLSQSDTVGSAIVEDGPGKEYEIYIKNEELVDKLKLLNYEDGFLKLGVVYKPILKHYFVKSKNVGEQFFLFTSLAAWLIKKSGDESYNMPQEFDDPNSTLANIMAAAKNKGIATDFTAAKLKSGAGENVIFILNSLADASLVHVGFQWQKMIPPKEEDEDTAVDEQDEDDDNDDIVEEPMNFLDDDDDDNVIEIDLKAQGLATESKNPLQSVLQSNTDAITWKQEVERVAPQLKITLKQDAKDWRLHLEQMNSMHKNVEQKVGNVGPYLDNMSKDIAKALERIASREKSLNSQLASMMSKFRRATDTRAELREKYKAASVGVSSRTETLDRISDDIEQLKQQIEEQGAKSSDGAPLVKIKQAVSKLEEELQTMNVQIGVFEQSILNTYLRDHFNFSANLLNIM
The following text describes a protein:
Function:
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
Sequence:
MCGIFGIYSYERLNVAKKIYYGLFALQHRGQEGAGIATSDGKNIHYYKNIGLVTDVFKNETLQNLFGYIGIGHVRYSTTGGKAVENCQPFVVKSSFGNIAIAHNGDLVNSDELRRELEMKGHIFTSSTDSEVIAQLLVRELLKTSDKIEAIKNTLKKLVGAYSLLIMFNDSLIAVRDPWGFKPLCIGRDESNIYISSEDCALTTLDAEFVKDIEPGEIIEIKDGEIISHKLDYGVSEYNPVNVDVPCIYRGAATCMFEYVYFARPDSTIDGISVYKVRKRIGKILAKEHPVDADVVSPIPDSGVTFALGFSEESGIPYYEGLIKNRYVGRTFILPSQNERELAVRLKLSPVKSVLEGKRVVLVDDSIVRGTTSRRIVNMVRKAGAKEVHLRIGCPKIISPCYYGIDMATKKELIASNKTEEEIGKAIGVDSIGYLSLEGLVKAIGRKDLCLACVTGKYPTEVNFEKILGRE
The following text describes a protein:
Function:
Needed for flagellar regrowth and assembly.
Sequence:
MLPEDIKPYVPLSFDENKKIAIDKHENNFDEDLIKKGYEQGFNKGYEVGYNEGLSKGYEEGFNKSQKEIKEKSDEFLRATQFFKNIIKELSLFKEKQIEFFLPQILKFAFKIAEKIVATKISLDREVTFSIVKETLKSVPFNEDRIIIKLNPEDYDFIANKINELDIDKAKLQIESSPDITKGGCWIETQSQHIVSTIEQRLKEIENALNSVISQQS
The following text describes a protein:
Function:
Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
Subcellular Localization:
Nucleus.
Sequence:
MPPNSPTGIKKTEIKTELKHWEHNFFKNNQRKPGREDVKANPRIAQLYKEYNQIKRRSSLPLKPPASPDTSRKRPFQSIENVTPRHSAILRTPGSVERTILGPTPQLTRKPIQIFEDISPLKPSPSKQDVSLVLPSDNSPVPPSPLFTTPTKANIPTPRKQNKIMETPTTLRMAVPSSPDLFHFAPPKRGLSTLLKELKAMEDEYGKDEEDVLHELESDEKSANADNYDEDPLNPFLLLARDTETDETTSKEQGSQEPQVRKLKVKRQHRRVKLPPSVPNAKSHLQPLEAIDEEEEIGTDEDDEEVMPNTTSMDGVPSESTILPSKVTEKPAKRRKIKGNLTIGLQVSSNYTAYKLRKGKAGGRFRRRRR
The following text describes a protein:
Function:
May be involved in recombinational repair of damaged DNA.
Sequence:
MLKTLNIRDFALIEEACIDFQKGMTVITGETGAGKSLILDAISSLLGGKSSPMEIRTSAPRYVLEGVFDLSKNPAAVEWLKEKGFPFESKELTLHRECGRDGKSRILINQSLASSTTLRGLGELLAEVHNQNDQILLLDRGEQLDIIDLHAGLVPLRNEVKECFLTYRSLKKRLEELRKSEEEKSKRIEFLNFQIREIRDVDLKEGEEEGLNQEEHLLAHGELLAENYEILSSHLADSESAILPLFPKLLSAAEKIKSIQPDFSKTLDSLQEIYIQLKEINSSILDEKEEIFFSPDRLQFVQSRLDLISKMKKKYGSDLAEILDCKNKAEQELEAMEKNSKNKESMEVEIEKIASRLASLSIQLSKSRRESLIRFESSLKLELEQLGMPGAAVQVVLRWEPNPEGEVSASGKSYIVNESGLDQLEFYFSPNPGEKPRPLRKIASGGEVSRVMLAIRSILGRQSNLRVLIFDEIDSGLGGEIAMDVARKLRNLAENHQLILITHLQQIASAANDHLKITKSVEGGRTFSKAEFLSLEERTLELARMISGQRVSKGALEHAKELLKKQAV
The following text describes a protein:
Function:
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Transports folate across the inner membranes of mitochondria (By similarity).
Subcellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MRYILNNNVEGTSALLGSTVATAFLQPFDFLKIRLQGSGFASGGDLNKFKRVGVIDTCKNVLKNEGIKQFWRGSSPTIVASGIAWGTYMHFYEAYKNILKSKYNVTQLNTFDHFICAVGASATQVFITNPIFLIKTRMQLQTPGSANYYTGIFDGIKKTVKVEGFKGLYKGVIPSLWLTFHGGIQMSSYEHIKFYFSSNSGKSLDSLNASEIFIASSISKFLASTILYPFQVVKTRLQDERNIPNQNNVRVYNGTKDVIFKILKNEGIIGFYRGLVPNTLKVIPNTSITLLLYEEIKKSFNYIINE
The following text describes a protein:
Function:
Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
Subcellular Localization:
Secreted.
Sequence:
MRAVCVFVLACVAVSGAPGVRGQDGPAEEELFQRAEDLLLRSILTQMEEQNSENDQPEWMEKRQHPGKRQHPGKREEDLEPEVEMERWRRQHPGKRAPLDLGMLEDPTALSELSKRQHPGKRYLMLLHKRQHPGRRELQEADGDSAELEKRQHPGKRRCEGWADAGCGLLELLDTSGAPEKRQHPGRRAELEDELPGLE
The following text describes a protein:
Function:
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MRELRHREVMRLARGHAANGTELLKHLRFHSTNFENILVWERGKNTTPDTVFSVAYSIYGAKRWQEKGACQNMTSRSCDLTGETGNIHEYYYAQVTALTESGLSASFRTQRFNPKTETVLKPPDVTFDPGVHSIRFILGPSLTLARDASGSPLALEDIFPNLLYHLRINVNQTHHMIKEGKEKEYEFPGLAPDTEYSGTVGIRIPSLAKHSPTHKFSVRTLPDRTWTYYFSGMSLFTMGFLVAVACFMTYKYINKNMQQPRVLDLQRVLTYHPLKFTREHVLTPVCDLVPPAAPPPPRAAPRPEGGLRDAPGFAQMPGDRLRREGPRPRRPGPCTEGPGPPALHLTALSAAHSASTFLRGVPDGRRVWRPGIASPPETEPGPTRPPAPGPGSGGRVVPQIQPGEAIGRARGRPSAPGRPADVPAGPGLALPGPGPAERLAGGQPAPAPPAVDPGRGWGARAGGPGLPPAPGPQPGLPPLVRSSGRRPRSGRARAGALASAQLPGGSPR
The following text describes a protein:
Function:
Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
Subcellular Localization:
Cell inner membrane. Cell membrane; Multi-pass membrane protein.
Sequence:
MLSSDIKGRMVILASFLLALILQTIPWPGTLDLFRPPWLLLVCCYWVLALPHRVNVGSALVMGLLWDLLLGSTLGIRGMMMSIIIYLVAMNFLVLRNMALWQQAIVIGLLSMGLEVLIFCGEYLIQNVTFNPLSLWSGVIACILWPWMFLLLRRVRRHWHVK
The following text describes a protein:
Function:
Cell membrane protein which plays a relevant role in coordinating membrane organization and cell wall remodeling during mating.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cell tip. Note=Localizes to the tip of shmoos which requires fus1, actin and lipid rafts.
Sequence:
MLFLHSVVQGTGTLCTLAAWILLALVMTGCQSSTTSKFQLFSLATNVAQINVGYFNMCVLSANATLICKPQFTGCPGLTSISLTDVRSKFLINEVHPWMIVFSFCVCGVSFLMGVVSSLPLIGRLEFLRNIRISLSFFSFFSILVTALFAHVAVSSFVMAVGNGTQNRVTASLGKKAMIFLWCSMGLVTLTGITDSIILLVTSRTKKIRKTILEKSKVLTPSSSFSSKSSTTKY
The following text describes a protein:
Function:
Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.
Subcellular Localization:
Secreted.
Sequence:
MADCISLHRGFILSFVLTLALHQVELSVFLPASEANNILLRWRRASSYLLEEFLQGNLERECYEEICNLEEAREVFENDASTDEFWSQYSGGFPCISQPCLNNGTCKDHIRSFSCTCAPGYEGKTCAMAKNECHLERTDGCQHFCHPGQSSYMCSCAKGYKLGEDHRSCSPSDKCACGALTSQHIRTQMTDDICRSWPSFPWQVRLTNSEGEDFCAGVLLQENFVLTTAKCSLLHSNLSVKADDDQQIRIKSAHVHMRYDKETGENDVSLLELEKPLQCPIPALPVCVPERDFAEHVLIPGTKGVLSGWMLNGIDLDRTLTMLSVTQTDGEECGQILNVTVTTRTSCEKGSEVMGPWVEGSVVTRQHKGTWFLTGILSSPPPPGQSHMLLLTSVPRYSMWFNQIMK
The following text describes a protein:
Function:
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
Sequence:
MNCAASVSVIMPAAGSGQRFGSQSNKLFAHLDGKPLWQHAIDRFQHRGDVRQIVLAVSEEDESRFREQIAAISSAVPIHLVRGGATRSESVGAALEQVKRFAAESAAANASTQTLVAIHDAARPLVRQSDLDRVIAKAAETGAAILAAPVSGTLKRATGDGSETVDRRNTYVALTPQVFAIDVICQAYARDRGRMATDDAQLVERTSHPVQLVTGSADNLKITFPEDLRIAEAILNECRSEFV
The following text describes a protein:
Function:
Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Together with methyltransferase THUMPD3, catalyzes the formation of N(2)-methylguanosine at position 6 in a broad range of tRNA substrates and at position 7 of tRNA(Trp) (By similarity). Involved in the pre-rRNA processing steps leading to small-subunit rRNA production. Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA.
Subcellular Localization:
Nucleus, nucleoplasm. Cytoplasm, perinuclear region. Note=Localizes to a polarized perinuclear structure, overlapping partially with the Golgi and lysosomes.
Sequence:
MRLLTHNLLSSHVRGVGPRGFPLRLQATEVRINPVEFNPDFIVRMIPKVEWAALLEAADHLHLIQVPKEPIQGYEHNEEFLRKMHHVLLEVEVLEGTLQCPESGRVFPISRGIPNMLLSDEETET
The following text describes a protein:
Function:
Negative regulator of both mitosis and meiosis. Required for the establishment of the G1 phase in the developing eye.
Miscellaneous:
MISCELLANEOUS: The rux phenotype is suppressed by mutations of genes involved in cell cycle progression such as CycA and string, and enhanced by mutations of intercellular signaling genes, Ras1 and Star.
Sequence:
MSAPEEHKETPLEVIHEFINGVDDGTIRRDLGEDCILSFYSRNVRGAKAITGFLRNQLTMRYKHEGFEEAAQIEWGDELLLKARFGRSFDSERRRIYEEKERTGTTLHVRPESDDEEVNEKFSSTLITPPRPSSYNLNSLKYVEACGLLNKRNEHIYGGLDMGESCAVHLTLGYRSTFLPGGQVSGFEICLAVYDRGLTSLKRSTLIPPLCSISFARRASARCNPTTDDEEDTEEDSTPPTARRCVRRTLFTEENTQKEEDADFIPVVEQEQPAPQEQPAPQQAEETGEVVIPVDISTALKTTNFSSCTPRKRQQATNGNEVVRKRATGPRRMRF
The following text describes a protein:
Function:
Involved in the regulation of xylem development and growth. May regulate secondary wall formation during vascular development by modulation of brassinosteroid, gibberellin and auxin hormone signaling pathways.
Miscellaneous:
MISCELLANEOUS: Plants overexpressing VUP1 exhibit severe dwarfism with extreme short and round shaped organs, and display extreme longevity before senescence.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MMDTFSCNSYEQNHPHDDDIDIDAHDHDSHGGDHQEESGWTTYLDDFSNQYRTTHHEENDHQDKSSYSLLATSTSLVSDAATHAFSGKSFPVNFPAKLKFGRGRTKKICEDDSLEDTASSPVNSPKVSHFEHIQTPPRKIEDYVSSSFVMGNIRGMGDHQIQIQEGGEQKVTLMRNLIDGNNNNNNNNMDLRSRGLCVVPISMLANFNGRC
The following text describes a protein:
Function:
Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's.
Miscellaneous:
MISCELLANEOUS: Present with 1380 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MGGEVLNNEGMPLAELKQETIPISRSESSESLNSLTSTRSSSSNRPKTYFCDYDGCDKAFTRPSILTEHQLSVHQGLRAFQCDKCAKSFVKKSHLERHLYTHSDTKPFQCSYCGKGVTTRQQLKRHEVTHTKSFICPEEGCNLRFYKHPQLRAHILSVHLHKLTCPHCNKSFQRPYRLRNHISKHHDPEVENPYQCTFAGCCKEFRIWSQLQSHIKNDHPKLKCPICSKPCVGENGLQMHMIIHDDSLVTKNWKCHICPDMSFSRKHDLLTHYGSIHTEEDIPLELKYKISDIQQLVQDHGVQLGNSKHSNEQDEEKISNRLRKRRKLTENNNVEFLQNEVDLEKRLESGENGLNLLLNTVGRKYRCFYNNCSRTFKTKEKYEKHIDKHKVHELKLKILQEKEENKTLVDQNHKEPFIIQKETQSAGDK
The following text describes a protein:
Function:
Component of the pupal cuticle.
Domain:
This protein is glycine-rich and contains several repeats of the motif (G/S)1-4(Y/F) like structural proteins from insect egg shells, egg cases and vertebrate cytokeratins.
Sequence:
MALVRVSCMLALLLIAGQGQAAPVKTEGSTLGLLGGGFGGSVGLSAGIGVGGGLYSGFGGGGYPGGYASGYPGGYGGGYSGYNGYGGSGFGGGYYPGGGYSGFGHRPHHHGGYYPGGGSYHNQGGSYGGHYSQSQYSNGYYGGGGYGGGGYGGNGFFGK
The following text describes a protein:
Function:
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
Sequence:
MAKSRYEYVKNFEQENHLLPDCHIVVRVDGRGFHKFSKFYNFEKPNDLRAIELMNKCAELIVSQFDDVIMAYGDSDEYSFLLRRKCSLFERRESKLVSTFASTFTSYYVALWGRYFNGNESRDETRETTEERKEEDMKEEERKEEERKEEERKAVKSEPRDDSRDSRSNELVIHMLPTFDARCVVYPNAQSIRDYFSWRQVDCHINNLYNTTFWTLVQQGNMTTQEAEQRLSKTVSKDKHELLFTEFGLNYNNEPDVFKKGTTIVKEFDTTGLSQRQVERKMKKMGRVRVMHCDIIRDGWWDERKWILE
The following text describes a protein:
Function:
Involved in mitochondrial genome encoded proteins translation.
Subcellular Localization:
Mitochondrion.
Sequence:
MPGRTPTYKLPPLPRLKVKKPVIKQEANRCLVLMSNLLQCWSSNGHMNPVCEKLATDLKACTSQNVMGSNQKPRKSTINYHAARLYDRISGKPHD
The following text describes a protein:
Function:
Plays a role in determining ER morphology.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Domain:
The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.
Sequence:
MGVFSIFGSKESFDPNVFEKELTSITEKINTNKQQISKLQQRQKYVRRSLSRYFIIIYLCIFGYCYATIPSSTIGKNRVQWFIRGQTRQHLLVLIGYPLFSVLTLRAVSYIFQFFINNKQSYLKSLQNKHKEKIEELKKITNFNKTNELINKYGNEKQPQVSLQKQEPQPISNQKQQDHLRNRHNKSGNLRDQAMKELNLPEDKQLSSQQKGQLPNTKQAPIPAIPQQPAQRTIQDRLLDILIGSDNSESVENRYALICFHCFAHNGLAPPHTEDPADVKFQCWKCGAMNGKGMLFEQPDMKFDSSKNSSSELINLEVKEKESGNLDHPGTENEEKEESTKKLQ
The following text describes a protein:
Function:
Thioesterase with a preference for ring-hydroxylated phenylacetyl-CoA esters. Hydrolyzes 3,4-dihydroxyphenylacetyl-CoA, 3-hydroxyphenylacetyl-CoA and 4-hydroxyphenylacetyl-CoA. Inactive towards 4-hydroxybenzoyl-CoA and 4-hydroxyphenacyl-CoA.
Sequence:
MSHKAWQNAHAMYENDACAKALGIDIISMDEGFAVVTMTVTAQMLNGHQSCHGGQLFSLADTAFAYACNSQGLAAVASACTIDFLRPGFAGDTLTATAQVRHQGKQTGVYDIEIVNQQQKTVALFRGKSHRIGGTITGEA
The following text describes a protein:
Function:
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions. Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein. Within the PAT subcomplex, CCDC47 occludes the lateral gate of the SEC61 complex. Involved in the regulation of calcium ion homeostasis in the ER. Required for proper protein degradation via the ERAD (ER-associated degradation) pathway. Has an essential role in the maintenance of ER organization during embryogenesis.
Subcellular Localization:
Rough endoplasmic reticulum membrane; Single-pass type I membrane protein.
Sequence:
MRAFHAFCVVLLVFGSVSEAKFDDFEDEEDIAEYDDNDFAEFEDVTEDSVTESPQRVITTEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFALVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPMSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM
The following text describes a protein:
Function:
Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a priming site for initiation of the synthesis of a complementary strand. Also plays a role as transcriptional regulator, DNA helicase and as key factors in site-specific integration of the viral genome. Regulates host PKA activity by interacting with host PRKX as a mechanism of interfering with helper virus propagation and promoting its own replication. Inhibits the host cell cycle G1/S, S and G2/M transitions. These arrests may provide essential cellular factors for viral DNA replication.
Subcellular Localization:
Host nucleus.
Sequence:
MPGFYEIVIKVPSDLDGHLPGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDECYIPNYLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQEQNKENQNPNSDAPVIRSKTSARYMELVGWLVDKGITSEKQWIQEDQASYISFNAASNSRSQIKAALDNAGKIMSLTKTAPDYLVGQQPVEDISSNRIYKILELNGYDPQYAASVFLGWATKKFGKRNTIWLFGPATTGKTNIAEAIAHTVPFYGCVNWTNENFPFNDCVDKMVIWWEEGKMTAKVVESAKAILGGSKVRVDQKCKSSAQIDPTPVIVTSNTNMCAVIDGNSTTFEHQQPLQDRMFKFELTRRLDHDFGKVTKQEVKDFFRWAKDHVVEVEHEFYVKKGGAKKRPAPSDADISEPKRVRESVAQPSTSDAEASINYADRYQNKCSRHVGMNLMLFPCRQCERMNQNSNICFTHGQKDCLECFPVSESQPVSVVKKAYQKLCYIHHIMGKVPDACTACDLVNVDLDDCIFEQ
The following text describes a protein:
Function:
Functions as a downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Functions as a downstream effector of ARAC11/ROP1 to activate calcium signaling that leads to F-actin disassembly associated with exocytosis in the tip of the growing pollen tube. Counteracts the ARAC11/ROP1-RIC4 pathway, which promotes apical F-actin assembly associated with vesicle accumulation, to control actin dynamics and pollen tube apical growth.
Miscellaneous:
MISCELLANEOUS: Over-expression of RIC3 in tobacco germinating pollen induces depolarized pollen tube growth.
Subcellular Localization:
Cytoplasm.
Sequence:
MATVKGLLKGLRYITQIFDEEKDKDMQIGFPTDVKHVAHIGSDGPATNVPSWMGDFKPQENENGQVVSRADANNNQIGEGVGLQELLPPTDKPKHKKTRRKSETVSQNGSPPRRNSSASASDMQPKNTRRHHRSRHGSIDSSNDPSVRRRRVVSVTTNDMEGSYPLSDSSTHSRKSTSRHRKPKGSGGGELSMKKTKGKTENPIVESVDTCNDNNISDKE
The following text describes a protein:
Function:
Critical regulator of mitochondrial DNA (mtDNA) abundance. Binds dsDNA throughout the mitochondrial genome without sequence specificity and controls mtDNA copy number by promoting its replication. Also plays important roles in mitochondrial metabolism and cell proliferation.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass type I membrane protein. Mitochondrion matrix, mitochondrion nucleoid. Note=Retained in nucleoids under mtDNA replication stress caused by ddC and EtBr.
Sequence:
MSDNPPRMEVCPYCKKPFKRLKSHLPYCKMIGPTIPTDQKVYQSKPATLPRAKKMKGPIKDLIKAKGKELETENEERNSKLVVDKPEQTVKTFPLPAVGLERAATTKADKDIKNPIQPSFKMLKNTKPMTTFQEETKAQFYASEKTSPKRELAKDLPKSGESRCNPSEAGASLLVGSIEPSLSNQDRKYSSTLPNDVQTTSGDLKLDKIDPQRQELLVKLLDVPTGDCHISPKNVSDGVKRVRTLLSNERDSKGRDHLSGVPTDVTVTETPEKNTESLILSLKMSSLGKIQVMEKQEKGLTLGVETCGSKGNAEKSMSATEKQERTVMSHGCENFNTRDSVTGKESQGERPHLSLFIPRETTYQFHSVSQSSSQSLASLATTFLQEKKAEAQNHHCVPDVKALMESPEGQLSLEPKSDSQFQASHTGCQSPLCSAQRHTPQSPFTNHAAAAGRKTLRSCMGLEWFPELYPGYLGLGVLPGKPQCWNAMTQKPQLISPQGERLSQVSLLERSSTHIRSLEPPAGLTTSNFSLMRLLGAVQKGWIRCNTTIRKSGFGGITMLFTGYFVLCCSWSFRRLKKLCRPLPWKSTVPPCIGVAKTTGDCRSKTCLD
The following text describes a protein:
Function:
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
Sequence:
MNLSKGTAAAYCSGYSEDVDVIREREYPLLKDTTYLDHAGTTLYANSLIHSFGRDLTGNLYGNPHSMSASSQLSAQRVDDIRLRALRFFNADPDEFDLVFVANATAGIKLVADALQNSPQGFWYGYYVDAHTSLVGVRELAKMGSRCFVNEDEVDSWISGLGSRREESLGLFAYPAQSNMNGRRVPMRWCEQIRAQKENADNMIYTLLDAASFVSTSPLDLSKIAAAPDFTVLSFYKIFGFPDLGALIVRKSSGDVFKHRKFFGGGTVDMVLTDGNPWHAKKQSSIHQSLEDGTLPFHSIIALDSAFETHGRLFRSMENVASHTRFLAKRLRDRMNALKHYNGTKVCQLYMSPNSSYDDASSQGPILAFNLRNSRGMWIGKSEVERLASIKNIQIRSGTLCNPGGTALSLGWTGADMLRHFSAGMRCGDDHDIMDERPTGILRISLGAMSSLTDVDTFIAFLEEFYVDKPPEGLPVPLTGNVSLHQPSFYVESLSVYPIKSCGAFRIPDGQRWEVRREGLAWDREWCLVHQGTGITLNQKRYPRMALIRPTLDLERCLLRITCGEANSRDGKTLEISLNRIGTNSLTTSLCQNASKPSTVCGDKVVLQAYTSPAVSRFFTDFLGVPCTLARFPPQSSTRFHSRATAAINRDQNYSQKQSPSMPGSFPQAPSSPDPYPTPILLSNESPLLLISRSSVNRLNESIKSASQPCSNPGSAASKKAVAADVFRANVVVAENISTAERPYIEDTWASLSIGSGPEQLRFDVLGSCERCQMVCVDQYTGQRGDEPYATLAKTRKIDRKILFGRHISPVGRPKDAENGCLGTIMVGDAVTPSYDNES
The following text describes a protein:
Function:
Structural subunit of M.tuberculosis pili (MTP), which are thin (2- to 3-nm wide), flexible, coiled-coil, aggregative fibers. Has a strong affinity for laminin but lacks significant binding affinity for fibronectin or type IV collagen. Mediates adhesion to the extracellular matrix, an event that would facilitate direct interaction with the host epithelium during infection in the lung or other tissues.
Subcellular Localization:
Fimbrium. Note=Part of the pili surface structure.
Sequence:
MYRFACRTLMLAACILATGVAGLGVGAQSAAQTAPVPDYYWCPGQPFDPAWGPNWDPYTCHDDFHRDSDGPDHSRDYPGPILEGPVLDDPGAAPPPPAAGGGA