lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MAVPGSNTILLLALTITVIQALTPSHYLTQRDVERLKSSLNQPFSNLETAFYSILGLSKLGAQVPDVKQACTFIKSNLDPNSLDSLFYAAQSSQVLSGCEISISNETKDLLHAAVSEDSSVSQIYHAVGALNGFGLPLASQEALGALTARLSKEETVLATIQALQTASYLSQQADLRGIVEEIEDLVARLDDLGGVYLQFEEGLEPTALFVAATYQLSDHVGTEPPFKEDQVIQLVNAVFSKKNFNSLSEAFSVAAAAAAFSQNRYHLPLVIVAEGSASVSHQQPVLRLQVSNVMSQPLAQASVMLERAKSSSTKNTVLQQTAFTPSGDHFDLNFMNAKPASGYYDFSINIEGDSRYIANVVELKVKVSTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKGKGSFTVDSHQNFALSFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDSKNIYKFELDTSERKNEFDSASGTYTLYLIIGDATLENPILWNVADVIIKFPEEDAPSTILSKNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFILWIRLGANISNFTFAPSTIIFHLGHAAMLGLMYVYWTQLNMFQTLKYLAILGTITFLAGNRMLAYKAVKRIAAEQSSRLAKYRTLRVENVKANRQSKGTIRSRGQVTSPGSEIRRAGSGVKQRQQTGSEDRSTGDQDQVAKATSGTLESGVRLLSQEQHSSSTRRKKENLKT
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MSSEESYLAILRYLTNEREPYAPGTEGNAKRKIRKAAACYVVRGGTLYYQRRQRDQQRFAELEVVLQAERRARLIRAAHLAPDGAHRTRLQTWQGLSQKYWWRGILKQVKDYIKECSKCQEKLDRSRSLSDPSEMLEELGLDVKSHEDSNETDDEVSNAASIPAASPKPVKKKPIAKHELVFVDSKGLVKQSSSKHCLSVLNQLNQQRLSNQFCDVTLLIEGEEYKAHKSVLAANSEYFRELFIEKGAVTSHEAVVDLSGFCKSSFLPLLEFAYTSELTFDFCSMAELAMLARHLLMSEVLEICENVHKQMEEKQITVYQKGDIQTVESTRNLAEQTAVQMPPVDGAEQPLPVELTASEVTATVNGAPSSLEPEEKGEPQPGILPPGPVEASADDLPKPVEQSEAIENGVKTVESISNSPTSARQPEPSVVEAMNTESPLEKETDENENCKVSAETISEDSSEMLKEKHGRQSREQSLSASPPESLASSQDDTYKSKLRQRSVSEGGYIRLHKGIEKKLQNRKTNPKSAIQQVAMKLVQRGKKMKQPKRETTENNEVEAQHKCTECGMVFQRRYALIMHTLKHERSKDYKCPLCKKEFQYGASLRAHLVRHTRKTEVNAAADGVEETGVSSVKGRTKREFICDICGRTLPKLYSLRIHMLKHTGVKPHACKVCGKTFTYKHGLKMHLALHEVQKQFKCDLCEKSFVTKRSLQEHMSIHTGESKYLCTICGKSFHRASGLSKHIKKHQPKPEVRGYQCTQCEKSFYEARDLRQHMNKHLDVKPFQCQFCGKCYSWKKDWYSHVKSHSVTDPYRCNVCGKEFYEKALYRRHVKKATHGKKGRAKQNLERVCEHCGRKFTQLREYRRHMNNHQGVKPFECLTCGVAWADARSLKRHVRTHTGERPYVCPVCNEAYIDARTLRKHMTKFHRDYVPCKIMLEKDTLQFHNQGTQVEHAISILAADMQEQETEISVGGEEIETVVVTGDTLEAIEAVATTEQCTSVSTLSDQSIMQVVNYVLAQQQGQKMAEVTQAMETVEVEVAHVTETE
The following text describes a protein:
Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.
Subcellular Localization:
Nucleus.
Sequence:
MERLELPFFSTMMNVWLFEQVKNTAEIKKALIQASQTNDEAEQSRLDWAFIDASMITSRQHLTTAVCQALVTQSHRALKTKTLHSEILWTLSPGTNIMEAIKKFGLGPQTNALLLVKLQPIEGDNQPSKEALDQAAQALVDGTLVKLDDHLGKSIVNWKGLRKIYKLNDDPVIRELEEQSKRTASDLEWHAMIDQLATATVALKSVAA
The following text describes a protein:
Function:
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MFADISAQHWAFAIYVIGAIAICLTMIGLAALLGGRAQGRTKNKPFESGVDSVGTARLRFSAKFYLVAMFFVIFDVEALYLFAWSVSVRESGWVGFIEATIFIGLLLIGLVYLWRIGALEWSPRKPQLNNKNTD
The following text describes a protein:
Function:
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
Sequence:
MMLQRMPSSCLHLLRHGNNLVTRCEMYAARRTMFSLARRSITSDTTSQTRWLCSGPLPLNQSYRATLQSRPVRVASLCHQSTSSSAVESTIAADIQQESDHLSVTVGNQTFKASYLWLRDHCRCSSCYEETCHENFVDIVALPDDITPKECHSKNGNLHLTWPDDHVTSYSIQWLQDNTPGQRSMAGSSQQLQPFYWDKASLAGNLPEDVHIDEVREGDGLKKVMENLHVYGLTFISGVEATQESTEEALHLVAPPMYTHYGRVWQYQNDGEIADAGYTSVSLKGHTDHTYFEHGAGGLALHCLYHDGTGGENTLIDGFHAAKLLKETHPDHYDTLLHAPVVGHYLDPTKDFRCYHNVLRHNVLTGQLQQIRFNPHDRSTLSYTSYEDAERFYAAYRTFGRIIESPESKFLTKLQPGRMVVFDNWRLLHGRAGFTGKRVMCGCYFNYDDFQNLKRTKANLDV
The following text describes a protein:
Function:
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.
Sequence:
MPGQEEPRYYSLIEPLRESSSPCGYCHSKSDSSHTYGVWAHDLSPQVYQMMMDRGWRRSGSYLYLPDRRTTCCPPYTIRCSASGFQASRGQRQAAYRWRKFIEGATEHSGAPKQQKPQSTFDLCQVLNFDDAQGTPPTIKEHEFQIRIEPAAFTEEKFKLYKKYQIEVHNDQAEEVTKKSFESFLCTNPFRSDRSVAKHACWLVDDQLIAFSVIDILTLGISSVYLVWDTDYAKYGLGRLASLQEIAWIQEWGASKLGEQFDWYYLGFYIHSCPKMTYKAEYSPSFLLDPSALDWWPLEDCIPILDASESNVTSFASSDVNQEGKKSDRADFSVKILTQTGAIETVKSSDPRVKEVVEKVGAEIVRLSLICI
The following text describes a protein:
Function:
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Subcellular Localization:
Nucleus.
Sequence:
MRTRSTASSEQPETEQKNLKAPTTVQTPSRTFILPSAASDDARFVTLPNPRTGEPNRYFFCPKLGVYEFTVVGSTPQFPRSILFAPKQDTKASIGNSDRSQVKGNISKVAELCVATPIDVMFFMIPLLNPATSTHTKRLFQPLDDILDSQDDLPDHLRRIFYNEDFRSVLQSRVEAVCDSVEAGDEKMFRFDEVKLLRELIAKAERLVAQGLPASLEERFVRQALVTPLMSVKREETIIGATASLEDGGEGESQDKQETQSTTTASVSTPSGVSTPTTELSAESNLESATRDNMARLLRISTVLSFIKESYLSPELCARLDELLATPETPVDFKPLQDHLQHIAELRAQALASQSLGDFSRKRGADDDEAAESRAEKKRRKEEEEKKKKAGESRGVRDLKKVDTSGMKKMSDFFTKAAPKKKS
The following text describes a protein:
Function:
Nuclear genome-encoded factor required for normal assembly of chloroplast polysomes.
Subcellular Localization:
Mitochondrion. Plastid, chloroplast.
Sequence:
MGVAATANATATATTLLKQFSTTKTSIFLPVIFKRFPSHSLFSRRKQLQFKRPAFSSFSSRTISSASTNEGITQGELSPKPSIPDLCLYNTMTRQKEVFRPRVPGKVGMYVCGVTTYDLSHIGHARVYVTFDCLYRYLKHLEFHVCYVRNFTDVDDKIIDRANILGEDPLSLSSRFCNEFDKDMVHLHCLPPSFDPRVSNHMTEIIDMIKQIIDNDAAYEIGGDVYFSIDKFPAYGRLSGRKLEDNRAGERVAVDLRKKNPADFALWKTAKPGEPCWNSPWGQGRPGWHIECSAMSNAYLGTSFDIHGGGMDLVFPHHENEIAQSCAACCNSTVNYWVHNGFVTVNSEKMSKSLGNFFTIRQVIELYHPLALRFFLINTHYRSPINYSNIQLETASDRLFYIYQTLYDAEEFLVEHKGGSLADSIPPVVQDCIIKFKSDFINSMSDDLNTPVGVAALSEPLKTINDLLHTRKGKKQALRVESLLAVEKEVRNVLEILGLMPSGYLEILNQLRKKALKRAGITEEHILQKIKERTSARQNKMYERSDEIRKELASLGITLMDGPVETTWRPTLPLELQEK
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MSFPNSSPAANTFLVDSLISACRSDSFYSNSASMYMPPSTEIGTYGMQTCGLLPSLAKREVNHQNMGMNVHPYIPQVDSWTDPSRSCRIEQPVTQHLPTCSFPTNIKEETNCCMYSDKRSKVISAEGPSYQRLLPDNCPVENSEVPVPGYFRLSQSYATGKPQEYNNNPESSSSLMLQLNPRSSSKQQIPPQLHMDKKMNENPASQDSGKVPSGESPDPKSALQEDRSCLAEVSVSSPEVQDKETKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAGDELKGKKRKYRDSHSGDEKSVKILPLSESSLPPLVTTISGFYPPENTRFQLLKKSNQSNRDASLIGRTERVQFEAKNQSTATVEANYCLAVADKTGRVKKIVPAKYLNTFERNILALQEKDKFLKKKHGTVSGTVMEQRANLGLAFGTRKSQKAIMEESANRVKAETLGDVKDQLVSNVQKATEALPTQEDIAAAQAQDRPIPPVNVGAESIEDAYKLEDIIPKEEFSAIYIKPLLENPDERNWAKLLPYRHSLFINERFQRLLSIEEVDQKRARILYYISLLQAFLFSRRSVGNRETLRKKLADPPEILIDGLIKRFTQTTGIGSVQVSSREVDKIICYILVLCLIVDNYSTDVLTLANDLNVKTMKANELFRTVGCRIMAYTETQRMALGLNKTDAKNHKRAVLKIPLEFPKPRRGRARN
The following text describes a protein:
Function:
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. May activate transcription by complex formation with other transcriptional factors, possibly members of the STAT family. Binds specifically to the IFN-stimulated response element (ISRE) but not to the IRF-1 binding site PRD-I.
Subcellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect. When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm.
Sequence:
MAALDSEGDAQKLRFGPWLLNAVSSGLYRGLCWIDPDRRIFRIPWKHNARKDVTSSDVEIFKAWAKASGRYEGNAEDPAKWKTNFRCALRSTHMFMLLEDRSKCNDDPHKVYAVASGVPNDRGSGGPVAGALQQQPQLLLNHHDLALENTPTDSTEGVAAAALTQVDLDLLQSVLQHCNISALGSQPTLWAHTGDALPEDALLLPGQDGCLPGPQFQDWRQLEEPLLLGNQPLTGGGCGQDGAGALPVSEECAIPAPSPAEELLFQSANPAPPPPAGDIGGLPPLLDITIYYRGKMVYQEQVDDSRCVLAYQPLDPAVAEQRLVLFPSPASLPDPRQRRYTEDLLEVAGLRLEQRAGQLLATRLKKCKVFWALSQQLEGGEPPLNLLHRDQETTIFDFRVFCTELRDFRDSRRERSPDFTIFLCFGQCFSSTKPKESKLILVKLVPQFCEYWYEQVQRGGASSLNSGNVSLQLSDSFNLFELIEQYHMQTD
The following text describes a protein:
Function:
Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure (By similarity).
Subcellular Localization:
Vacuole.
Sequence:
MALKIKIPETSQSSDEYSRWTVYHIEVAFPNGGKHVVFRRFNEFVALDAQIRPNDYNSRLCKLPSKSWVSSTVTNEKLRESRRLALQAYVQCLSETPWIKMPVVKKFLNIKDESEDETQGQFLGPTDWIQVFQDCKRNLHMYRVDLMSGKSITIGVQTKNVYAIKSLMDNLSESLDKLELANALGPGEILRRKDMLEQLGSEFLSFKRLVKNANSPVAPPSASSQLNSSNPSSPFRPLSASTDKQSNTSLNRVLGKNRMPETQTTKKLDNVGLYNMQNQTMEDQDMQAESLLPIIQRQKELSKMINQEVVEQNSMLDELSNEAYANQKKLHRTRAGLRKLG
The following text describes a protein:
Function:
Promotes leaf senescence mediated by abscisic acid (ABA), salicylic acid (SA) and jasmonic acid (MeJA), probably though the induction of expression of senescence-associated genes (SAGs) and defense-related genes.
Subcellular Localization:
Cytoplasm. Note=Present in cytoplasmic foci.
Sequence:
MASATSNNPASSSMSPRRISGNHGSPTASVAQSPRRPSRQVSSPWTQIVRGESEPIAAAAAVAGPSSPQSRAPIEPIASVSVAAPTAAVLTVEAAAGDEKSEASGGQDNAGKKPVWKRPSNGASEVGPVMGASSWPALSETTKAPSNKSSSDSLKSLGDVPSSSSASSSVPVTQGIANASVPAPKQAGRANPNPTPNHSRQRSFKQRNGASGSANGTVSQPSAQGSFTELPSHNPSPRGQNQKNGFASQNHGGTENPSQRDSYRNQNGNHHQSHGGRRNQEHGNQNWTFQRSFNGREGNAQSQRGTPAFVRHPSPTVQPIPQFMAAQPFPSHIPFPTELAQSSYYPRMPYMTPIPHGPQFFYHYQDPPLHMKLHKQIQYYFSDENLITDIYLRGFMNNEGFVPLRVVAGFKKVAELTDNIQQIVEALQNSPHVEVQGDFIRKRDNWQNWVLRRNPTGSGPQSVDRADAVAKRLGNLSVDQSSADPIGGSSSQLQPTEALSDDQQQSSSTAPVSNHNAPDGANR
The following text describes a protein:
Function:
Probable S-adenosylmethionine-dependent methyltransferase which mediates cantharidin resistance.
Miscellaneous:
MISCELLANEOUS: Present with 4380 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MPKTSYLNKNFESAHYNNVRPSYPLSLVNEIMKFHKGTRKSLVDIGCGTGKATFVVEPYFKEVIGIDPSSAMLSIAEKETNERRLDKKIRFINAPGEDLSSIRPESVDMVISAEAIHWCNLERLFQQVSSILRSDGTFAFWFYIQPEFVDFPEALNVYYKYGWSKDYMGKYLNDNQREILLNYGGEKLRSLLSDRFGDIEVTIYSPSDPNASTVTAENSQFLWRAAITLNQFKEFVKSWSIYTSWARDNPSKPDIADIFINELKEICHCEDLNVPLKIEWSTFYYLCRKRE
The following text describes a protein:
Function:
Component of the insoluble part of the cuticles.
Subcellular Localization:
Secreted.
Domain:
The small repeats A-A-P-[AVI] are also present in many proteins constituting the protective envelope of other species.
Sequence:
MQKLIVFFTTIAAAQAFLLPSGGGGGCGCAPPPPPPPCGCGAPALPPLQLPRFELPRLSLPSLGGGCGGPAPCAAAPIAAPAGGYATAPAAPVGGYATGPAFGGAAPIGGAYQAAPAFVGAAPVGGAYQSGPAFGGAAPAGGAYQSGPAFGGAAPAGGAYQSGPAFGGAAPAVGGAYQAGQAAVESAPLGGAAPAGGYQASAPAAVEAAPAAGGYQAAAPAGGAYAGHKKN
The following text describes a protein:
Function:
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. Likely functions in some aspects of cellular RNA processing. Function plays an important role in regulating axon regeneration by inhibiting central nervous system (CNS) axon regeneration following optic nerve injury.
Sequence:
MKPLKTRLGFIVFQCKYAVLRYCRQAVFERPYNGRFASHAAFPARRNNPKNHYDVMKLLPTATQREIKSAYYELSRIYHPDLNSSAEARERFAELTLAYNTLSRLETRREYDKQIGTYYMTRSLTRKSEGERVLRLMDDLVEIDATGIEQLYAIETMELCFQTSSFLGAGIPLNTILGLPVRLNNIHGPKASYGLQPHDVRMLHLLRQMCSGTLVASKGSSTVTFLPGDLQAGIFSSEGGHSGSVSLLAESALPCLALAPEPVYSRNNILNLKGITHLANGLHMDFFDKVYRPIVEKFGFHFSIEIKRRSYFPQSSGKVVIRSFPVTNLKAVDLTTPGRLVKITGWTSVAGAKPIRIAQVMSKLTRSALKDRFPGVDIYVESLRERDSRVDGTGQAVMILGETSSGMMLSGTALWRRGMSNEEVVQKAVNMFTQNSSHSICVDSLVQDKLLPYMALAKGQSSIRTSLITPHTKAAIAGLEAMSKVKFQVTSDVIGGSKTMVISCNGLGITR
The following text describes a protein:
Function:
Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro) (By similarity). Depending on context, may modulate tumor-related angiogenesis (By similarity); [ANGPTL4 N-terminal chain]: Mediates inactivation of the lipoprotein lipase LPL, and thereby plays an important role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. Has higher activity in LPL inactivation than the uncleaved protein.
Subcellular Localization:
Secreted. Secreted, extracellular space, extracellular matrix. Note=The unprocessed form interacts with the extracellular matrix. This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4.
Sequence:
MRSAPTARAALVLCAATAGLLSAQGSPEPPEAPRFASWDEVNVLAHGLLQLGRGLREHVERTRGQLGALERRLSACGAACKDPEGSAVPPLTAGNLVPSQSDAAPETLHSLQTQLKAQNSKIQQLFQKVAQQQRHLEKQHLRIQNLQGQLDHLAPMHLGHGVAKAARRKRLPKMTQPAGPAHNISRLHRLPRDCQELFEEGERQSGLFQIQPQGSPPFLVNCKMTSDGGWTVIQRRQDGSVDFNQPWEAYKDGFGDPKGEFWLGLEKVHRIMGDRGSRLAVQLQDWEGNAESLQFPVHLGGEDTAYSLQLTAPVASKLGATIDTPSGLSLPFSTWDQDHDLRGDKNCAKILSGGWWFGTCSHSNLNGQYFHSIPRQREQRKKGIFWKTWRGRYYPLQATTMLIQPTVAEAAS
The following text describes a protein:
Function:
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MMAAETAAAGVASRLAAARILAAVFDQGRSLKAELTAALPGVSDPRDRALVEAICFAVLRRRPAYDVALRQWLERPLPPRDAELKALLMAGFAQLDVLQLPAHAALSATVEACRALGRPRQAGMVNAVLRRAQREGFPAVADDAGWPSWLRKQLRADWGDQAEAIFVESARMAPMWLRVPRARVSPAEYVARLAEQGITAHTDPVLADAVRLDTAVPVSQLPGFAQGDVSVQDGSAQQVADALALAPAARVLDACAAPGGKAAHLLERHPQLQLTALDVDARRLERVRQTVQRTAPDRTVRLHPADAADTAAWWDGQPFDAVLLDAPCSATGVVRRQPDVLLHRRADDIDALCALQARLLEACWRTLRPGGQLLYTTCSLLKRENQTQIEAFLQRTADAQAQPLGAQFGHAAGAGRQRFPGEQQCDGFFYALLLKAS
The following text describes a protein:
Function:
Likely catalyzes the dephosphorylation of O-phospho-L-serine into L-serine.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MMVSSHLGSPDQAGHVDLASPADPPPPDASASHSPVDMPAPVAAAGSDRQPPIDLTAAAFFDVDNTLVQGSSAVHFGRGLAARHYFTYRDVLGFLYAQAKFQLLGKENSNDVAAGRRKALAFIEGRSVAELVALGEEIYDEIIADKIWDGTRELTQMHLDAGQQVWLITATPYELAATIARRLGLTGALGTVAESVDGIFTGRLVGEILHGTGKAHAVRSLAIREGLNLKRCTAYSDSYNDVPMLSLVGTAVAINPDARLRSLARERGWEIRDFRIARKAARIGVPSALALGAAGGALAALASRRQSR
The following text describes a protein:
Function:
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of mitochondrial (kinetoplast) genome stability.
Subcellular Localization:
Mitochondrion matrix, kinetoplast. Note=Localizes predominantly to the kDNA disk.
Sequence:
MWDGPLRSRQNLRTVAKLRSSGCPLTQSAIHPTTTSPSEGETASEILQGQASAGYIEEQQLPATSSQLEMSGDSNAASDNNVVIMTKRQRDDLSQASQAEVLSRLRTEDAQGPAENNGAQSDLALHSCDMEERVDSSKLNLNHVTVNKHSPPASKSAGISQQNDDGGCGASENVDNTTTAASKQRGKLLLDSSSSNCTPKQQAQQAVTQVPEWELSHEQERIFDIVVNHRRSVFLTGGAGTGKSHLLRAIIAALPLSTTFVTATTGLAALNLGGTTLHSFSGCGFVDQHTSTHQMVYRNVLGRKKARANWRKCRVLVVDEVSMLDAWFFDMLEYVARHIRGCRKPFGGIQLVLSGDFLQLPPVNKHSPKQETRLCFEAKSWPRVNPLVCTLSHQFRQKDKEFFSLLNEVRVGALTAPSLGLLSSLSVITTVSFVDEEKLKLKREVGAEAVDIITDSKGRTRRQRQDGFTILRARRSEVDAINTEKFGELDTEIYSYKGAHRGEGHFPSDLPSTVSVRAGCRVMLLANLDLSAGLANGSIGTVESFVSSKLHQTANPSTKDDLQHLADHMMLPVVRFDHKGKQGPGDGGGAAAGRLVVIEPHRWTMRQGDSDVSCSIQIPLQLAYAITIHKSQGMSLSHVNVDFAGIFEEGQAYVALSRCTDVANLVIENFDAQRVNPNIKALAYYRALEFVGTEHREAEKKLIDNGNKMNPWGPYDVEDFEASDDDNGGAVKKEVVENLTYDAENISCMVEQFRQRYMPQYIMFSTLRRRVLSNTEDAARVKGALLVMDTTSLLALTNMTGPTSLYQTIFTERGNMMRVPRVVKEELLFLASTDVKEVSSVTTPTLHSFCSTCSSTPCSTGFSYDFVEVVSCALSIMENAKCDFLLDEQREGEANSLPPVIQEWRSLSPLLMLNSSPDTGEKDAPSVIGFGERSREQHHSTLMFASFLVSRYSGNGAVYVCTETVELAARALAIGLRVCSIAYLCNRARRVN
The following text describes a protein:
Function:
Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
Sequence:
MSDNTTLAPPTSNQGPTTPRKGPPKFKQRQTRQFKSKPPKKGVKGFGDDIPGMEGLGTDITVICPWEAFSHLELHELAQFGII
The following text describes a protein:
Function:
Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MNIKDDMVVQFNYTLRDEKGEVIETNEGREPIAYLHGHDNMMPGVENAINGKAVGEKFTVTLPCAETYGQRIEGEAAQQRVSVKHLLGASVWKPGMTAVVHTDHGQRQVTIVKVGKFMATVDVNHPLAGRDLTFDIEVVGARDASDEEIAHGHAHGVGGHHH
The following text describes a protein:
Function:
May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death. May play a role in the embryonic development.
Subcellular Localization:
Cytoplasm. Cell membrane. Apical cell membrane. Basolateral cell membrane. Cell junction.
Sequence:
MSSRRLGSSRARGRDLAHEVKHFGGLTKHLKKIIFDSNNCLTELKTSDHFEEEVISTLVLPPVADEIVGKVTKNPPALVIFGQTYTSKATLVNKIFREDLFQIVDDSDNNKTWRAVHLKYGSQRNTRLTLTNSFELLNEEPGSPVMRNSWTGIPRVEMLVKEEHQKDACMLSATTEATLNHPLLQCKLQILVTPHNCPGISISQAYNVCTHNVLPVLLYCFDKDQLSEENLRDLQELQNCAGTLPILFVDCREPSEPLVAHRERRLVEDAHEDFDDDSAYDTDERIEGERERHNGLDARLRRRCRPTPNDRPSVIDQLSRAGFISSPEENGRMRGVLDVFTIVNQVEDLHNSAAIVQFIRRSLQYYLIRCCTAMHDLHQHCMNLFITTAFDMQRDILVTPKRIEYARQRENELFDSLKDLTNQKQEQLRSLIQSTVADMTEDLLEQAGNYRFTDLEVSQEGKIQSQKDIKRCTEQIQDLVLARLNACVVEKLIGSVELLRESFLGTLQRCLASLEKIDGDLETSTTVALRQILNAAYQVEVSVRTSSSVVRIIWERMKEFFQSIKPFKTPTRVDTEWKRKVAQTMINNLDESKLAKSICSQFRSRLNNSHESFSTSLRQLEQKHSGRLEKTEEQRMKVRKVYAPRLARLALESTSLRDMVLYGMPKLEREIGRGQYGVVYSCRSWGGVTHCAVKSVVPPDDKHWNDLAMEFHYTRSIAEHDRIVAVIGSVIDHGYGGMGCSPAVLLLMERMQRDLHTAIKANMELPERLHVALDVAEGVRYLHSLGLVHRDIKLKNVLLDKHDRGKITDLGFCKPEAMMSGSIVGTPIHMAPELFSGKYDNSVDTYAFGILLWYVCAGHVKLPQAFEQCANKDHLWTSVKKGVRPERLRPQFDDASWNLMKSSWAGEPSERPLLGEVQSKLQDIYTKALAKREAEGGGGGGAKEQQNLKSDTL
The following text describes a protein:
Function:
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MLPTLTALLCLGLCLSQRINTEKQTLPKPIIWAKPSIMVTKGNSVNIWCQGAQSASEYQLYFEGSFFALERPKSSRSMNKVKFFISQMTSHTAGIYTCFYQSGELWSESSNPLKLVVTGLYDTPTLWVHPGPEVTLGENVTFSCHLKTATSKFFLLKERESNHIQHKYGNIQAEFPMGPVTRAHRGTYRCFGSYNDYAWSFPSEPVTLLITGEVENTSLAPTDPVSSLDYWEFDLSTKESGLQKDSAFWDHTAQNLIRIGLACIIVMALVWLLAEDWLSRRKDHEKLNRLTSWECRGRRRMHRYHEEEQRDAISMRELKATPGDM
The following text describes a protein:
Function:
Part of an ATP-driven transport system CT_415/CT_416/CT_417 for a metal. Probably responsible for energy coupling to the transport system.
Subcellular Localization:
Cell inner membrane; Peripheral membrane protein.
Sequence:
MTKQMLLENVSFRYGKTGPLIVDHVSCEVYSGDFIGIIGPNGGGKTTLTQLMLGLLQPVCGSISTYSVQDHRPLSIGWVPQHFSYDAAFPITVKETVLSGRLATLPWYGRYTQEDHEAAEEALLTVDLIDYKDSCFSHLSGGQIQRVLLARALAARPEFLLLDEPTANIDPVNQQKILQILSALNKHCTILMITHDLHHTAGCFNRVFFMNKTLTTLADTTTISERFCCNTFGRCP
The following text describes a protein:
Function:
Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MDQSVEDLFGALRDASASLEVKNSAKEQVSLQQEDVLQIGNNDDEVEIESKFQEIETNLKKLPKLETGFDALANKKKKKNVLPSVETEDKRKPNKSDKNDNDWFTLPKPDDNMRREVQRDLLLIKHRAALDPKRHYKKQRWEVPERFAIGTIIEDKSEFYSSRMNRKERKSTILETLMGDEASNKYFKRKYNEIQEKSTSGRKAHYKKMKEMRKKRR
The following text describes a protein:
Function:
May be involved in G protein-linked signaling.
Subcellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein.
Sequence:
MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY
The following text describes a protein:
Function:
Probably involved in the biogenesis of the COX complex.
Subcellular Localization:
Membrane. Mitochondrion inner membrane; Multi-pass membrane protein.
Sequence:
MIQKKLGSYKASLSLIKTGHYVFGTTHCSHNSTNRNLASTISIRNRPLRWYSTESSPALASNPIETMKSSDYNTRHKNRFGGGWLWLIPAVTLGLGIWQVQRLQWKLHLIDQAQSRIHQIPRVLSCESAKATVPSRDQFTRVTVTGTFLHDKEIMVGPRVFHADTSQDQGGGILGGGKPDIGYFIFTPMVIAESTVGAENAIVLINRGWIPKDECDRPHRKAITGLVTVDGVIRDGEPCGKLQSWTISNKPEKGEWYSIDLEKISQWTGSLPIIVQMVSDSPINQKFSPNNGQPYRPKVHAKLRNNHMEYAITWFGLCAVSTLMLASKKRIFRKR
The following text describes a protein:
Function:
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
Subcellular Localization:
Cytoplasm.
Domain:
The N-terminal domain is an archaea-specific tRNA-editing domain that hydrolyzes incorrectly charged L-seryl-tRNA(Thr). Catalysis of tRNA editing is performed by the charged tRNA itself.
Sequence:
MQLLLIHSDYIEYETKKQTPVAEKIEESLKSGRLEEALTAFTAVESVDEANPEEAIEKAVSEIEKVAAQVKTNRIMLYPYAHLSSDLSSPKVAVQVLKGIEAALSGKYEVKRAPFGWYKAFTVSCKGHPLSELSRSIHPEGTAKAAVKPEAAGEKEEVVSEALKAEGTARSYWRILTPDGELHEVETFDLTPYPKLQQFVNYEISKSRAVERAPPHVELMRRLELADYEPGSDSGNMRYYPKGRLVKSLLENYVLDVATEFGAMEVETPLMYDMNHPTLKKYLDRFPARQYSIESDKRQMFLRFAACFGQFLMNHDMTISYKNLPLRMIEMTRYSFRKEQRGELVGLRRLRAFTMPDMHTLCEDMNQAVSQFKEQYDLCIDVLENVGIHIDDYEVAIRFTRDFYESNKELVVNMAKTVNKPVLVEMWDTRFFYFVLKFEFNFVDALAKASALSTVQIDVENAERYDISYVNADGKLERPIVLHCSPSGAIERCIYALLEKAAMETEEGKVPMLPVWLSPTQVRIVPISEKHLAFAEEVSKKLDCRVDIDDRDLSIGKKVREAGREWVPYVVVIGDKEMEEGTINVTVRAESEQNKPSKVQITPEELNARIRGEIAGKPYRKLPLAKYLSARPKFF