lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Catalyzes ghrelin acylation at 'Ser-3' using preferentially octanoyl-CoA, hexanoyl-CoA and decanoyl-CoA as acyl-CoA donors leading to ghrelin activity (By similarity). In vitro uses also acyl-CoA donors of different lengths from short-chain (C2) to long-chain fatty acids (C16) knowing that acyl-CoA donors from butanoyl-CoA (C4) to dodecanoyl-CoA (C12) are more efficient compared to longer acyl-CoA donors, such as myristoyl-CoA (C14) and palmitoyl-CoA (C16) that are not efficient (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MIDLLWISSDGHPQLFYQFINIPFAFLFHCLSSQGHLSIINRYVYLAMGGFMLAIATMGPYSSLLFLSAIKLLLLIHYIHPMHLHRWILGLQMCWQTCWHLYVQYQIYWLQEAPDSRLLLAISALMLMTQRISSLSLDFQEGTISNQSILIPFLTYSLYFPALLGGPLCSFNAFVQSVERQHTSMTSYLGNLTSKISQVIVLVWIKQLFSELLKSATFNIDSVCLDVLWIWIFSLTLRLNYYAHWKMSECVNNAAGLGVYFHKHSGQTSWDELSDGSVLVTEASSRPSVFARKWNQTTVDWLRKIVFNRTSRSPLFMTFGFSALWHGLHPGQILGFLIWAVTVQADYKLHRFSHPKLNSLWRKRLYVCVNWAFTQLTVACVVVCVELQSLASVKLLWSSCIAVFPLLSALILIIL
The following text describes a protein:
Function:
Required for efficient RNA interference (RNAi). Plays a role in germline development.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MHKAPISTLILDSLFSNMMLAEMMNDDQLELLKHQQTGIQPVVPEGCNLYWSSLNVTGPETKPTNFVDRFRNNMPKRRVKEILHNVSGMAESGKLLAILGSSGAGKTTLMNVLTSRNLTNLDVQGSILIDGRRANKWKIREMSAFVQQHDMFVGTMTAREHLQFMARLRMGDQYYSDHERQLRVEQVLTQMGLKKCADTVIGIPNQLKGLSCGEKKRLSFASEILTCPKILFCDEPTSGLDAFMAGHVVQALRSLADNGMTVIITIHQPSSHVYSLFNNVCLMACGRVIYLGPGDQAVPLFEKCGYPCPAYYNPADHLIRTLAVIDSDRATSMKTISKIRQGFLSTDLGQSVLAIGNANKLRAASFVTGSDTSEKTKTFFNQDYNASFWTQFLALFWRSWLTVIRDPNLLSVRLLQILITAFITGIVFFQTPVTPATIISINGIMFNHIRNMNFMLQFPNVPVITAELPIVLRENANGVYRTSAYFLAKNIAELPQYIILPILYNTIVYWMSGLYPNFWNYCFASLVTILITNVAISISYAVATIFANTDVAMTILPIFVVPIMAFGGFFITFDAIPSYFKWLSSLSYFKYGYEALAINEWDSIKVIPECFNSSMTAFALDSCPKNGHQVLESIDFSASHKIFDISILFGMFIGIRIIAYVALLIRSYNNT
The following text describes a protein:
Function:
Histone chaperone-dependent acetylase that modifies 'Lys-9', 'Lys-14', 'Lys-23', 'Lys-27', and 'Lys-56' on histone H3 (H3K9Ac, H3K14Ac and H3K23Ac, H3K27Ac, and H3K56Ac) to promote nucleosome assembly, genomic stability, DNA repair and transcriptional regulation during mitotic S-phase. Its residue selectivity is influenced by the acetylation status of histone H3, and also the presence of histone chaperone ASF1 that shifts selectivity to 'Lys-56' when H3K14Ac is already present. H3K56 acetylation weakens the interaction between the histone core and the surrounding DNA in the nucleosomal particle and drives chromatin disassembly. Autoacetylates. Independently of acetyltransferase activity, stimulates histone deposition by VPS75. Involved in regulation of Ty1 transposition.
Miscellaneous:
MISCELLANEOUS: Present with 1140 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSLNDFLSSVLPVSEQFEYLSLQSIPLETHAVVTPNKDDKRVPKSTIKTQHFFSLFHQGKVFFSLEVYVYVTLWDEADAERLIFVSKADTNGYCNTRVSVRDITKIILEFILSIDPNYYLQKVKPAIRSYKKISPELISAASTPARTLRILARRLKQSGSTVLKEIESPRFQQDLYLSFTCPREILTKICLFTRPASQYLFPDSSKNSKKHILNGEELMKWWGFILDRLLIECFQNDTQAKLRIPGEDPARVRSYLRGMKYPLWQVGDIFTSKENSLAVYNIPLFPDDPKARFIHQLAEEDRLLKVSLSSFWIELQERQEFKLSVTSSVMGISGYSLATPSLFPSSADVIVPKSRKQFRAIKKYITGEEYDTEEGAIEAFTNIRDFLLLRMATNLQSLTGKREHRERNQPVPASNINTLAITMLKPRKKAKALPKT
The following text describes a protein:
Function:
Unlike the other SLC37 members, seems to lack glucose-6-phosphate antiporter activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Sequence:
MDFPVNTRRMAGRRGFFSQYTHHHLAAFLLTFFSYSLLHASRKSFSNVKVSVSSQWTPSDLNSSAYIVLPNETWNGNTLFPNTKSATLFLGLLDTIFLFAYAVGLFISGIIGDRLNMRLVLTFGMCSSAITMFVFGTLTEWLQFYNKIFYCLVWIVNGLLQSTGWPCVVAIMGNWFGKSGRGFVFGLWSACASVGNILGAFLASSVLKYGYEYAFLVTASVQFAGGIIIFFGLVTSPKELGLPDTGEGEMDRAAQEEGANKPLIGGNDEGDDESNYSIQSDDVVITPKAIGFMQACCLPGVLLYSLAYACLKLVNYSFFFWLPYYLSNNFKWKEAEADQLSIWYDIGGIVGGTVQGLISDLMKMRSPVLTVSLLLAVGALFGYSHSPNDKVMNAFIMSITGFFIGGPSNMISSAISADLGRQEMVRGSSEALATVTGIVDGTGSIGAAMGQFLVPLIQNSLNWMWVFYFFIFMICMTTVFMVPLIVRETRDWLRQRRSSRLER
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLLRCEIKNEYGLGDPELYEESGSDDPEALLEGVAMAGLVGVLRQIGDLAEFAAEVFHGLHEQIVTTSARGHRLMLCVQQLEIEFPAVEKKVLSQTTHSHLPNNAGIDWHPSNHLDQNLITQQDMPRFVLNSYEESREPPQLFILDKFDVAGAGACLKRYTDPSLFKTNDSSFRTLESEIQREKKSHKTRKKGTHSMHTKTINSFMKPDEKSIPTSDPKSLSLKRAKLKTRHVNSLTNRIGTSYMECIIDSQIVDQNQNDIRGKYSFSGNKKSVEAALEVHEIVIDSSSREKNYREIKQSQFIIKHNRIEEDIDGPGKEKGMNRVPESLLLPNDEVSKSPLVIGSPTFNDYREFNDTEKLSKNVLHESEGMAVLDMAGSGAGEIGNNVSKLDYDNELENYVDALTAMESEMETDYQSSVPNSPHKESPRASSDSGRVGKHAKLTSSLDEKCSLDSVEHLGNFIDTGLTEKNEDHTLECEKSLSFSSMNLLEKNSNKDLDTTSLSELPENMEESTPVWPSSLPENMKESAIFISSDSFKIVNESTRIMPSESPKTMKESAAVKLSETPDNINDNYICRSKESDVLNAIHEPCYASYDPQSASGSLEILDEYLSASEDPNAMLSDQERDIKSTTKGLDEGNLICTDILSKSEETVLVGDSGNPDVLSDAPSPRQMDNNDGLYPIMTYNLIHENELFSENIVDGSSPDAHTHSSTCSIPEKTVLNNFSQDSSLHSVKEPSELINHNLEIDDGIVKAPHFDGDSENLRHEKLNENVDDDIVYGNIQNLQSKHFPTKENEVFSETKTGDNPCPHLLEVASDTFNDKERNDSIIVTEIPVDSIMIENSASVFCSETSSNSIEDDKSFELNSISPSSQDTSGSEFKMHDSIQELKDKIQVESVSGSEFKIHDSTQELKNKIDVESLSGSELKMHDSIQESSKIHVESVSGFEFKIYDSTQELKNKIDVESLSGSELKMHDSIQESSKIHVESVSGSELKMHDSIQESSKIHVESVSGSECKIHDSTQELKNKIDVQSLSGSELKMHDSIQESSKIHVESVSGSEFKIHDSTQELKNKIDVESVSGSEFKIHDSTQELKNKIDLESVSVSEFKIHDSTQELKNKMHVESVSGSEFKTQEESVSISEFKIHDSTKELKNNKLSSPYDNTLGLTSEETSALLCSKQENENTSSKLGPEDHPFPADMNNHGTVDSTDSFVALVPNNTQIDSSNNTELSYSQSDVREVDMVLINSDQSDGSLAVEFQSSTPEGFEELDVQQPQIIRKMETPVCLDNSCVSSINVLKELLADETKQVTGVSENGIKKNDSDDSLCDTHHQNHSEVEETYKSIQSSSELFVKSLENISVTNMHTQINLLPQNGLQDSVADTPLPPLPPLQWRLGKHGLGSKIPFGATSNPTLRSKSPIKSFLNSSASGILPLLENNQQPQVNDANSGSRQTVSS
The following text describes a protein:
Function:
Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.
Miscellaneous:
MISCELLANEOUS: Present with 339 molecules/cell in log phase SD medium.
Subcellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Sequence:
MKTAYLASLVLIVSTAYVIRLIAILPFFHTQAGTEKDTKDGVNLLKIRKSSKKPLKIFVFLGSGGHTGEMIRLLENYQDLLLGKSIVYLGYSDEASRQRFAHFIKKFGHCKVKYYEFMKAREVKATLLQSVKTIIGTLVQSFVHVVRIRFAMCGSPHLFLLNGPGTCCIISFWLKIMELLLPLLGSSHIVYVESLARINTPSLTGKILYWVVDEFIVQWQELRDNYLPRSKWFGILV
The following text describes a protein:
Function:
Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination.
Subcellular Localization:
Secreted. Note=Secreted in plasma.
Sequence:
NVISNIMADFVQTRAASIISDRDVEVDISLTRSPVITATHLESHHKGHFVYKNISEDLPLPAFSPTLLGDTRMLYFWFSEQVLDSLAKVAFQDGRLQLSLAEAEFRAVLETWHFNPNQEIIPELFSASLTSPGRVTVHCPGRPTISCQNKGVVVSSPVVIEFLFPHKDGQDSVTHTFEEDIVTTIQASYSKKKLFLSLSDFQIKPKMASNMDEDSASIQSFLQLMITTVGIPEVMSRLEVALTTLINSKGLDLFDIINPEIISRDGFLLLQMDFGFPEHLLVDFLQSLN
The following text describes a protein:
Function:
Probably involved in bacterial recognition and uptake by its host (human).
Subcellular Localization:
Cell membrane; Lipid-anchor. Cell surface. Note=Immunoelectron microscopy indicates this protein is displaced from the cell surface.
Domain:
Fragments of the mature protein (residues 77-96, 97-116 and 117-136) prevent uptake of M.tuberculosis by a human macrophage-like cell line.
Sequence:
MTSTLHRTPLATAGLALVVALGGCGGGGGDSRETPPYVPKATTVDATTPAPAAEPLTIASPMFADGAPIPVQFSCKGANVAPPLTWSSPAGAAELALVVDDPDAVGGLYVHWIVTGIAPGSGSTADGQTPAGGHSVPNSGGRQGYFGPCPPAGTGTHHYRFTLYHLPVALQLPPGATGVQAAQAIAQAASGQARLVGTFEG
The following text describes a protein:
Function:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MPTKKTRNLDRAKTARMSQKKKEHSAARSSRKTAVQTSKAAIAEQEEEEQVELDPWERARKILHVSSTPSWLPCREEEFAELEAALTESIEEASGSCLYISGVPGTGKTATVHSVISSLQNKARNGELNPFKFFEINGMKVTEPSQTFILFWEFIAKNLVDPNSPPKRTSAREALKNLENYFNSPEPDRETCVLLVDELDQLVTRKQEVIYNFFNWPNQAHSRLIVIAVANKMDLPETELNGKIRSRLGSNRIQFKPYNHHQLMEILEMRLEELKDAVFVKDAIQWVSKKISSLTGDVRKALDLCRSTLERVEKENEIRMENGEEARLVQVKDVIDTYEQMISSGVSRFIKELSPHQSIMLLSISKAIKVAGIPEVELGDVISRHIRLANTLGFQPEPSHEELMTVVSSLQNMKLILNESSSFDYFSRIKLEVTDSDLRLITKNDKRFSSITI
The following text describes a protein:
Function:
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
Sequence:
MAEPISKQQMKCDEATAKSLIVDNWNSVNSSVSETAQRCGRSPDSVRVVGVTKYVDAEITSWLVEAGCHDLGENRPQLLESKFQTLDDSNIRWHQIGNLQRNKVRRLLPAEPLVHAIASERLLDALHNECLLQSRSIDGLIEINVSEEEAKTGLPIDQLEPLLVHWRELAGSSNAGLNINGLMAMAGWGTDETAAARQFAKLRELRDQMESSTGISLPELSMGMSGDYPAAIAEGATLVRIGTRLFQGVLPTG
The following text describes a protein:
Function:
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens. Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation. The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity.
Subcellular Localization:
Cell membrane.
Sequence:
MAFWLRSLGLHFRPHLGRRMESFLGGVLLILWLQVDWVKSQKIEQNSEALNIQEGKTATLTCNYTNYSPAYLQWYRQDPGRGPVFLLLIRENEKEKRKERLKVTFDTTLKQSLFHITASQPADSATYLCALD
The following text describes a protein:
Function:
Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL).
Subcellular Localization:
Membrane; Single-pass type I membrane protein.
Sequence:
MEGAGSRGAGPARRQGARGLGLLLLLWLLPGLAAPQDLNPRGRNVCRTPGSQVLTCCAGWRQLGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKERCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHVGWWGRSCNNQCACNSSPCEQQSGRCQCRERMFGARCDRYCQCSHGRCHPVDGTCACDPGYRGKYCREPCPAGFYGPGCRRRCGQCKGQQPCTVVEGRCLTCEPGWNGTKCDQPCATGFYGEGCGHRCPPCRDGHACNHVTGKCTHCNAGWIGDRCETKCSNGTYGEDCAFVCSDCGSGHCDFQSGRCLCSPGVHGPHCNVTCPAGLHGVDCAQACSCHEESCDPVTGACHLETNQRKGVMGAGALLTLLLGLLLSLLGCCCACRGKDSARRELTLGRKKAPQRFCGSFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLDPPSGLEQPSPSWSSRASFSSFDTTDEGPVYCVPHEEATADSRDLEATAALTEVAAVSLEPTGTSTPGEEAAVLPASSDSERSASSVEGPSGALYARVARREARPARTRNEAGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAAPSPPPAGRKAAPSPSGRKRTPSNSSVQPPGLTEEAPGPASPTPPRARARGRGLGLSEPTDAGGPPRSAPEAASMLAAELRDKTRSLGRAEKPPPPQKAKRSVLPAATVRTASASEASGSEKAAASAPAPETPRKKTPIQKPPRKKSREAAGEPSRAGTAPGAS
The following text describes a protein:
Function:
Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MNLIISSSLLLMRLLSRNVTLRRANIQTILSRLYSEGPTELSKAQLQKFKSQEQRFKRRLHSVHRKFADVPDNSEFQGQHHVYLEDGKRIYRSTLGHGKQETVEVFNADWGEGGYGSIQRVRLSPTETMLAATVKKDHHEKTRCMLIRLNGVSCTQRVMLVLDNVLSFEWATDDVLFYSTQESLRSLHVFRLHLIDSAVQTTLVYEEKDPKFFVEVSRSRDQRLVTINCSSKTSSEVWFVDSKSPFSFPSLTQSRQPGLLYHVEHSDNSLFILANTGPDQEYQLLRASLASPSMPHWVPVFSAVPGTVIKDLELLQDHCVFTVKDSHCRLQIQTLTTKEPYQLNTLQLPQWACDLSPQRVGTVDRGSFSFLLSSPVHPPVRYLYSSKGQKLSITEDSIKHISIPEFNTTRLQATSHDGTMVPLTLFHMPAFSELCKAPLLLHVYGAYGVDLNMTFSPEKRMMLEDGWTLAYCHVRGGGERGLSWHRAGSVLQKQRGVEDLAACIQTLHRLGVSGPDLTALTARSAGAILAGALCNQNPQLIRALILQAPFLDVLGTMQDTSLPLTLEEKGEWGDPLIREHRDNIASYCPCHNIQPQLYPSMLITAYSEDHRVPVSGVIKFVERLKKAIQMCTTQVDINARVPSVILDIQPGADHFGPEDFHLSLNESARQLAFLYTELGLSLDQQRTRRRRK
The following text describes a protein:
Function:
May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
Subcellular Localization:
Cytoplasm. Melanosome.
Domain:
A pair of annexin repeats may form one binding site for calcium and phospholipid.
Sequence:
MKGFGSDKEAILELITSRSNRQRQEICQNYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYGDAKEIKDAVSGIGTDEKCLTEILASRTNEQIHQLVAAYKDAYERDLEADVIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVHQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKLCGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVHPAGDFNPDADAKALRKAMKGLGTDEDTIIDIVTRRSNAQRQQIRQTFKSHFGRDLMVDLKSELSGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFKRILISLATGNREEGGEDRTRQEDAKVAAEILEIADTSSGDKTSLETRFMTILCTRSYQHLRRVFQEFVKMTNYDVEHTIKKEMSGDVRDVFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMISRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGHFLKALLAICGGED
The following text describes a protein:
Function:
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
Subcellular Localization:
Nucleus.
Sequence:
MPKATRKKKEKKADFVKAKLKLGKGKKQASNTTDTSFKARSIALPGQEALNRALQISEGAGPSEPTTANGLTLEDIFIRLRHPNSVVRKEALGGLREILQVDVSREVGKVLRALGGLVADDDAAVRKGLLGLLDWYLAHLSQSILSPHLPLLVLQASSALSHIFPEIRLDACKLVHLMLQYVPSHVVSSWPYESSNILEGLRLAVGLGGEKGVNSQIGRLTGGAKLVTMKAMREFVRIGLENGMTQKWGGGYLEDRQSSRGKFKVVKEESGLENVQLEGWLVGTRMAKLVGDGDAWELGRLGSLGGKGDEEGVVSVLSQLYIQLHPLLLSTFLENAPTAFSPSMASVTPASEDIPLALCVMTASLTELLADAILTRATPDANTPELRQVKNCISDFHRRMTGWFPFNSRTAPTPSGVTPGFELSLAYARLAVLLSPRPVDLTFTKHSTKRGKEVRWRERVKATEEAWKTMRESERAKGKGKIGQNQWAMEEVADWVVEVLEPKKDVLAPSLTPEAYSALLPIVWALLAQPPCLASDDTDIPSHVGSAFISHLIRQGSTSPIREIGEEFLIALILVHEKKYPILPFYIVPQSPLRPMIKGWFEGIPKTLFELGTKNQSASERLLRFLLVIGSRGEGAYEQPYSLIDPATFPSLTPKLAPFWHLQHPSKGSIPGAWTKFNSGEVKRLGLDVAMVWKQWNGLRLSDAIGRVCGHDQWGSYWRR
The following text describes a protein:
Function:
Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
Sequence:
CHRRIVQYKTAYYSFYLPVACALLMAGEDIEKHTDVKHVLVEMGTYFQVQDDYLDCFGNPETIGKIGTDIEDFKCSWLVVKALEICNGEQKKLLEENYGKPDPENVAKVKALYHEINLQGVFAEYESKSYEKLTTSIEAHPSKAVQAVLKSFLGKIYKRQK
The following text describes a protein:
Function:
Modulates blood feeding of female mosquitoes on vertebrate species by binding and sequestering different mediators involved in the host response (By similarity). Binds serotonin, noradrenaline, histamine and tryptamine. Inhibits histamine-, serotonin- and partially noradrenaline-induced smooth muscle contraction. Exhibits vasodilating activity.
Subcellular Localization:
Secreted.
Sequence:
MIRQVITSYFLTVCLLALVQGETVQDCENKLPTSLKSRLCEIRRYEIIEGPEMDKHIHCVMRALDFVYEDGRGDYHKLYDPLNIIELDKRHDVNLEKCIGECVQVPTSERAHVFYKCLLKSTTGRTFKKVFDLMELKQAGKVPQHQRYTAEFVQIMKDYDKALNC
The following text describes a protein:
Function:
Magnesium transporter that may mediate the influx of magnesium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MERRRPQIAPSPPVSRRKAAAAASQEWLVVPAAGERRAGEFGRHRIMEMTGLPARDLRMLDPLLAYPSTILGRDRAIVVNLEYVRAIVTAAEVLVRDPSNPRLRPFLQELHARLALPDAATTTPATTDGGDDQGNVPISGSAKIPPFEFKVLEVCLEHTSKCMETETSVLESEAYPALDELTTKVSTSNLDDVRQIKNRLVQLSGRVQKVRDDIEHLLDDHTDMCEMYLTRKLAFQGVNNESSVNVDSNKHAFPDQDHDHEKEEEDRGGDTASSHGSSACVKHVEELEMLLEAYFVEFDGTLNKLCHLRDYVDNTENYINLMLDKKQNQLLQMGVMLTTATVVVTAGIVVVSLFGMNIHIELMADPETPEMARIKNMKFWETTWGTVAGCAAIYLLAIYAGKKSKYLQ
The following text describes a protein:
Function:
Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction.
Sequence:
MKDESAFFTIDHIIKLDNGQSIRVWETLPKKNVPEKKHTILIASGFARRMDHFAGLAEYLSTNGFHVIRYDSLHHVGLSSGCINEFTMSIGKNSLLTVVDWLTDHGVERIGLIAASLSARIAYEVVNKIKLSFLITAVGVVNLRDTLEKALEYDYLQLPISELPEDLDFEGHNLGSEVFVTDCFKHNWDTLDSTLNSVKGLAIPFIAFTANDDSWVKQSEVIELIDSIESSNCKLYSLIGSSHDLGENLVVLRNFYQSVTKAALALDDGLLDLEIDIIEPRFEDVTSITVKERRLKNEIENELLELA
The following text describes a protein:
Function:
Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTPRGPGRLQRLSQCRPQRGSGGPARGLRQLALAAMLGALAVTVSGCSWSEALGIGWPEGITPEAHLNRELWIGAVIASLAVGVIVWGLIFWSAVFHRKKNTDTELPRQFGYNMPLELVLTVIPFLIISVLFYFTVVVQEKMLQIAKDPEVVIDITSFQWNWKFGYQRVNFKDGTLTYDGADPERKRAMVSKPEGKDKYGEELVGPVRGLNTEDRTYLNFDKVETLGTSTEIPVLVLPSGKRIEFQMASADVIHAFWVPEFLFKRDVMPNPVANNSVNVFQIEEITKTGAFVGHCAEMCGTYHSMMNFEVRVVTPNDFKAYLQQRIDGKTNAEALRAINQPPLAVTTHPFDTRRGELAPQPVG
The following text describes a protein:
Function:
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.
Subcellular Localization:
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Sequence:
MFEILNGQRHDRSALILYGTETGNSQDVAEELGRVIERLHFMTRVCEMDEVDIKELLKYQFVIFTISTTGQGEFPKNSRKFWNSLLRKRLPPNCLSHVNFTTFGLGDSSYAKFNFAARKLHKRLEQLGGNEIYPRGEADEQHEEGVDGTFLSWYIDLRKKLLELYPLPDGLEPIPDDVLLPPKYWLELKNESTTLTEKLNSPPDNSGETDQTDLDSLNSKIDGKSQKTSISEDGTMSNISGFGLGLRFDHGYDEPKPSNRLTGPYKHDELESVDRVLPESGNFTDVHNGVHAIIHKNKRITPLSHWQDVREITIAVRSREFSPWPGDTMSIYPKNFPEDVQTLIDLMGWNEVADVKLHFKPRSPDWFGAKNLVSSQKDLHLVDEDQTLRELLIHNLDFQAIPKRHFFEIMANYTDDPTHKARLLEFRDPLYTDELYDYTTRPRRSILECLQDFPSVKLPWKDATTIFPIIRAREFSISSGGIMHIAPEDLKKNAKNVRGSKRSKDVEALDKPMKEYHFQILVAIVKYRTVLQKVRNGLCSRYLATLPEKSVITISYNSNSSFYKAPGVLPERPLILVGAGTGIAPLRSLIWERSKKMLSSPAGRPVFGKTLLIYGGRNRDADYFYGANWADSSLGVDAHPVFSRDGPQKVYVQDEIRKQGQQIADLLTKHNALIYVCGSSGGMPKAVRLAFLGVLQKYGDMSFEEAENFVANMERSKFYIQETW
The following text describes a protein:
Function:
Selectively catalyzes the oxidative deamination of acidic amino acids. Protects the organism from the toxicity of D-amino acids. Enables the organism to utilize D-amino acids as a source of nutrients. Enables the organism to utilize D-aspartate as a source of nitrogen and carbon.
Subcellular Localization:
Peroxisome matrix.
Sequence:
MPPSDPIIVLGAGVIGLTTAVRLLEAHLGANVHILADHWPSDALDAQYASTIAGAHHLSFADDGDARQRRWDMRTFDVLYDEWKAVGERTGLMALTQTEMWEGATSHLAVYEGNPDFRVLDPRTAPCSNITHMVSFTSLTIAPTVYLAALEARVRDLGAKLHRAHVPSLGALRTDPALLALYTRPPAAVFVCAGLGARHLVPAPEAAALFPTRGQVVVVRAPWMRAGFTRQVGSLGGGEGGTRTYIIPRCNGEVVLGGTMEQGDWTPYPRDETVTDILTRALQICPDIAPPYARSWPKDDQVAALRSIVVRDAVGFRPSRAGGARVALASAAGMRVVYNYGHGGAGWQSCWGCAEDAVALWAGGAGGARL
The following text describes a protein:
Function:
Probable transcription factor involved in plant development.
Subcellular Localization:
Nucleus.
Sequence:
MVEQTVVREHIKARVMSLVRSAEPSSYRNPKLYTLNENGNNNGVSSAQIFDPDRSKNPCLTDDSYPSQSYEKYFLDSPTDEFVQHPIGSGASVSSFGSLDSFPYQSRPVLGCSMEFQLPLDSTSTSSTRLLGDYQAVSYSPSMDVVEEFDDEQMRSKIQELERALLGDEDDKMVGIDNLMEIDSEWSYQNESEQHQDSPKESSSADSNSHVSSKEVVSQATPKQILISCARALSEGKLEEALSMVNELRQIVSIQGDPSQRIAAYMVEGLAARMAASGKFIYRALKCKEPPSDERLAAMQVLFEVCPCFKFGFLAANGAILEAIKGEEEVHIIDFDINQGNQYMTLIRSIAELPGKRPRLRLTGIDDPESVQRSIGGLRIIGLRLEQLAEDNGVSFKFKAMPSKTSIVSPSTLGCKPGETLIVNFAFQLHHMPDESVTTVNQRDELLHMVKSLNPKLVTVVEQDVNTNTSPFFPRFIEAYEYYSAVFESLDMTLPRESQERMNVERQCLARDIVNIVACEGEERIERYEAAGKWRARMMMAGFNPKPMSAKVTNNIQNLIKQQYCNKYKLKEEMGELHFCWEEKSLIVASAWR
The following text describes a protein:
Function:
Pheromone produced by juveniles which activates a small number of vomeronasal organ sensory neurons and exhibits a powerful inhibitory effect on adult male mating behavior.
Subcellular Localization:
Secreted. Note=Secreted from the lacrimal gland into tears.
Sequence:
MNSVPVMLFSISILLAAMLTEGRGLTQTQKESIFSAEHKSDLKSYLEMLVCRRLRDVPESVIHISKVSKEILPDDLLSTYLLELLVCFDKDKLVQSKGIVFNTIKRLLTNT
The following text describes a protein:
Function:
Involved in beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
Sequence:
MTMAALHFHNVTLGYDRHPAVHHLNGEVAPGALVAVIGPNGAGKSTLLRGIVGILRPLDGSIHLGGLDSRDIAYLPQSAEIDRSFPISVFDFVGTGLWRGTGLFGGIGKAAREKILRAIGAVGLNGFENRPIGTLSGGQMQRVLFARVLLQDARLIVLDEPFNAIDSKTTTDLLALVKRWHGEGRTVLAALHDMEMVRSHFTETLVLARGPVAWGPTAEVLTPENLMVAMRMCEAFDDSAAACAADDARSRAA
The following text describes a protein:
Function:
Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
Subcellular Localization:
Cytoplasm.
Sequence:
MTSPENVRRVACVGAGVIGGGWVAHFLARGYEVTAWDPAPDAEPRLRRLVEAAWPTLTRLGLAEGASTDRLTVTDTLEQAVADAEFVQESAPEKLDLKRDLLARLDAATPPGVVIASSTSGYPMTDMQTTAADPSRLVVGHPFNPPYLIPLVEVVGGERTAAAAVAWASRFYEVAGKSVITMDNEVPGFIANRLQEALWREALHMVASGEATVRDIDLSITEGPGLRWAVMGPMLTFALAGGEGGMAHMLDHFGPSLKSPWTRLAAPELDKELYDAVVAGCDEAADGRSIADLVAERDRGVVEVLRATGRLGPEEDSR
The following text describes a protein:
Function:
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular Localization:
Secreted.
Sequence:
MSTLSSSSSSSSFSTTYVTLTLFIILIISTLINTSHSLVSRPPPTAIKAARNAATRGHHRQLSIDYYAKSCPEVEKLVGSVTSEQFKVAPAIASATIRLFYHDCFVEGCDASILISSKSGSKELAERDAWQNKDLPIEAFEGINKAKALVESKCPGVVSCADVLTISTRDYVHLAGGPYYEVKKGRWDGKSSKASLVPSNIPQTNATIDELLKLFASKGLTTEDLVVLSGAHTIGYAHCKYVINRIYDYKGTNQPRPDIDPKLLSALRMYCPHHGGNEDIVVPFDVTTPYTFDHAYYGNLEKNMGLLMTDQALYLDSRTKSIVQSLSKDKQKFFQAFAQAMEKMGTIHVKRGKKHGELRKDCSSHI
The following text describes a protein:
Function:
Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAMFLLLHFAFLIDVKDYVLTDGSTITPLCQKGYFPCGNLTKCLPRAFHCDGMNDCGNGADEENCGDTSGWATIFGTVHGNANNVALTQECFLNQYPQRCDCKETELECVNAGLKSVPTISSNVTLLSLKKNKIRSLPNKVFVKYTELKKMYLQHNCIRHISRKAFFGLHNLQILYLNHNCITTLRPGVFKDLHQLTWLILDDNPITSISQRLFTGLNSLFFLSMVNNHLEALPKQMCAQMPQLNWMDLEGNGIKYLTNSTFLSCNSLTVLFLPRNQIDFVPEKTFSSLKNLGELDLSNNMIMELPPHIFKDLKLLQKLKLASNPLLYLHKNQFESLKQLQSLDLERIEIPNINTGMFQPMKNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRIFVWVIAFITCFGNLFVIGMRSFIKAENTTHAMSIKILCCADCLMGVYLFFVGFSDIKYRGQYQKYALLWMESLQCRLMGFLAMLSTEVSVLLLTYLTLEKFLVIVFPFSNIRPGKRQTSVILICIWIVGFLIAVIPFWNEDYFGNFYGKNGVCFPLYYDQTEDIGSKGYSLGIFLGVNLLAFLIIVFSYIIMFCSIQKTALQTSEVRNHIGREVAVANRFFFIVFSDAICWIPVFVVKILSLFRVEIPGTITSWIVIFFLPVNSALNPILYTLTTSFFKDKLKQLLHKHRRKSIFKTKKKSLSTSIVWTDDSSSLKLGILNKITLGDSIVKPIS