lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA. The NAD-cap is present at the 5'-end of some RNAs and snoRNAs (By similarity). In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity). Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs and mediates their subsequent degradation. Has decapping and 5'-3' exonuclease activities. Has decapping activity toward incomplete 5'-end cap mRNAs such as unmethylated 5'-end-capped RNA to release GpppN and 5'-end monophosphate RNA. The 5'-end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTVSCDKDENKVDQLGESLSQLRISTRKNNKPSQKKGSLVLSCKKFPHVSVNYVVDKTPKLLTDCKEVHNCSYIINDATLLWNEASRKPRLRPEVCTYIKDSKWENKAVKDSFIGIDLTKGYDDYVPLDRNVLNSLVILKEAYQRYEKTLNPEKTTFVSLRHHIIDIIMCPFLDEPLSLLMTVQPDKNILISVDKSKDKPNGIHETRNSFNKKICYTGFALEDLLIESPTEGHILEHELYYSIVHGSLNDEIDLLIQAEMDSINTLTDTYTEIKSSVHFKLGNTYHRRKLLRMWIQTNLLPKSDLLIGFRNSYSNELEQLKAYKIQDIYHKINNSSIVGKPGKFYKFNPNVANDWFQHIFQVLKQNLLLLSQESTSTTFKVQIDTNLTLSISPASQFVTALG
The following text describes a protein:
Function:
A possible function of virB4 might be to provide the energy, via hydrolysis of ATP, for translocation of virulence proteins of the transfer of a T-DNA-protein complex across the agrobacterium membrane.
Sequence:
MLGASGTTERSGEVYLPYVGHVSDHIVLLEDGSIMTMAHVSGMAFELEDAEMRNARCRAFNTLLRNIADDHVSIYAHLVRHDDVPPSPARHFRSAFSASLSEAFEERVLSGKLLRNDHFLTLIVSPRAALGKVRRRFTKRYRQKENDLTAQTRNLEDLWHLVAGALEAYGLRRLGIREKQDVLFTEVGEALRLIMTGRFTPVPVVSGSLGASIYTDRVICGKRGLEIRTPKDSYVGSIYSFREYPATTRPGMLNVLLSLDFPLVLTQSFSFLTRSQAHSKLSLKSSQMLSSGDKAVTQISKLSEAEDALASNEFVLGAHHVSLCIYANDLNNLADRGARARTRLADAGAVVVQEGIGMEAAYWSQLPGNYKWRTRPGAITSRNFAGLVSFENFPEGSGSGHWGNAIARFRTNGGTPFDYIPHEHDVGMTAIFGPIGRGKTTLMTFILAMLEQSMVDRAGAVVLFDKDRGSELLVRATGGTYLALRRGAPSGLAPLRGLENTAASHDFLREWIVALIESDGRGGISPEENRRLVRGIHRQLSFDPHMRSIAGLREFLLHGPAEGAGARLQRWCRGNALGWAFDGELDEVKLDPSITGFDMTHLLEYEEVCAAAAAYLLHRIGAMVDGRRFVMSCDEFRAYLLNPKFAAVVDKFLLTVRKNNGMLILATQQPEHVLESQLGASLVAQCMTKIFYPSPTADRSAYIDGLKCTEKEFQAIREDMAVGSRKFLLKRESGSVVCEFDLREMREYVAVLSGRANTVRFADQLRKVQGDNPSAWLSEFMARYHEAKD
The following text describes a protein:
Function:
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.
Sequence:
MSIRVLKAGDVYRIEGPAKVVVRRGQVYATGVVYTEGQSFTVLRARRLVIKALSESEVELVLGPGALLERVDPREEIIDEWESKTASIDPKGVIVIVGMIDVGKSTMTAMLGNKALARGYKVAIIDADVGQNDLGPPTTVSLARLTKYITHLRQLVAEKSIFLQATSLERIWPRAIEQIARAVDFAKRSWQVDTIILNTDGWVLDEEAVVFKRRLIDVIKPSLIIAIQVEKELAPVLDGYNNVVVLPPPPQVRSRSREDRKIHREMGYGRYIFPPVELAIPLDKIPICNLPIFKGIEIGDELKRILARAIGTGVLKAYQVGNRVYAIIENDAWVVRRVSGFQVIGLPIDFEKGLLVGLEDAEHFLVGLGVMKRIYYDRRKAIIYTSSEVERRIGEVKCIRLGLVRLDDNFNEVEKAYSLLKVEHE
The following text describes a protein:
Function:
Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity).
Sequence:
MPKNKKRNTPHRGSSAGGGGSGAAAATAATAGGQHRNVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGIKNALASKMLYEFILERRMTLTDSIERCLKKGKSDEQRAAAALASVLCIQLGPGIESEEILKTLGPILKKIICDGSASMQARQTCATCFGVCCFIATDDITELYSTLECLENIFTKSYLKEKDTTVICSTPNTVLHISSLLAWTLLLTICPINEVKKKLEMHFHKLPSLLSCDDVNMRIAAGESLALLFELARGIESDFFYEDMESLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETIKFGPERMYIDCWVKKHTYDTFKEVLGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKCRDKRADVGEFF
The following text describes a protein:
Function:
Transcription factor acting as a flowering repressor, directly repressing FT expression in a dosage-dependent manner in the leaf vasculature.
Subcellular Localization:
Nucleus.
Sequence:
MASSSELSLDCKPQSYSMLLKSFGDNFQSDPTTHKLEDLLSRLEQERLKIDAFKRELPLCMQLLNNAVEVYKQQLEAYRANSNNNNQSVGTRPVLEEFIPLRNQPEKTNNKGSNWMTTAQLWSQSETKPKNIDSTTDQSLPKDEINSSPKLGHFDAKQRNGSGAFLPFSKEQSLPELALSTEVKRVSPTNEHTNGQDGNDESMINNDNNYNNNNNNNSNSNGVSSTTSQSNRKARRCWSPDLHRRFVQALQMLGGSQVATPKQIRELMKVDGLTNDEVKSHLQKYRLHTRRPSPSPQTSGGPGPHLVVLGGIWVPPEYTSAHGGTPTLYHHQVHHHHTNTAGPPPPHFCSSQEFYTTPPPPQPLHHHHFQTFNGSSGGTASTDSTHHQVTDSPTVEGKSPESGGGERKGLAALREECEDHSNINGSEITLKF
The following text describes a protein:
Function:
May have S-adenosyl-L-methionine-dependent methyl-transferase activity.
Sequence:
MLDPTSERDLFDQENMEEISQLASLEMSGDVVANTNSTVVLEKPSYPDSVYVTAANIFQGIRIQRSPDKVIINYGSEPLQPSSSRSEDESFQRLSYELAFSTLKYQDILESILIDSYIFSSTTIASQLNSLIIVMLYDFQDRKFQPRILSENEETIPEVQEVENLLNGFKTKLAAALARCRIKHDALSIYHILPETVRKQEQRASTLPLYAWINTSKISLEEVYNNLRRKGYSKVKSITSVNEKVYAVDQHCFNVLIFPAHLKTDLLNIDLIKDYKLIFQDKSRSLAVHSVKALINIDDDVLMVNTGSWYTVAHMSILTSGHTSKIFVCGIQQEEKDFNARKLFTRMGCQNIEILHETFLSIESKDHRLQNVKVILLLPRCSSLGVSNPVEFILNEHEDKSLLQDLSQGGLPKDKLETLVQQQFEQLTHAMKFTKVQAIVYCTCSVSKEENEDVVEKALEYQSSGVKMQPYRLSPPVLPLCTLKEIELSMDRFFRLEPSDMNNGCFLSILTRERDPSETVSVKDVLARAAAKGLLEGVEVGKTLKRDKKRKKSKALPSRAPHHGDPLRDHLAVDGNDTSNVQMKISELLHRESKISTSTKMSAPAKTVSQAGTSSQVRKPSKPLSTPLVRNFSRPVERPTNFVRARPEGKVIPLKPIEIVLPPVIFPLSSQGPRVQMPATHFYYRFIGSKVGVPRYLTSSTSRRKEKVKESTTSSHVRHPRPWL
The following text describes a protein:
Function:
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Miscellaneous:
MISCELLANEOUS: Present with 279 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Sequence:
MTNSSEKQWERIQQLEKEHVEVYRELLITLDRLYLIRKHNHAVILSHTQQRLLEIRHQLQINLEKTALLIRLLEKPDNTNVLFTKLQNLLEESNSLDYELLQSLGAQSSLHKQLIESRAERDELMSKLIELSSKFPKPTIPPDDSDTAGKQVEVEKENETIQELMIALQIHSGYTNISYTI
The following text describes a protein:
Function:
Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Sequence:
MDTHNISNGRTQALMIPADEALQTILSVAQRLQSVTVPLFDALGKVLAEDIHAPDPLPPYRASVKDGYAVIASDGPGEYPVIAEARAGNDGVGVTLTSGAVAYVTTGGPIPDGADAVVQVEDTEGIENTSGESKRVKILVHTSKGVDIRPVGCDIEKDAVVLKSGERVGAAEIGLLATMGVMMVKVYPLPKIGVLSTGDELSEPTTKLLGRGQIRDSNRAMILAAATQQECKVVDLGIARDDEEELERILDSALCSGINILLTSGGVSMGDKDFVKPLLASRGTVYFSKVLMKPGKPLTFAMINLKSVESTRQNKILAFGLPGNPVSCLVTFHLFVVPTIRHLAGWANPHLFRVQARLHHPIKTDPVRPEFHHAIIRWEVNDGSGNPGFVAESTGHQQSSRLLSMKSANALLELPATGSVISTGTTVSAIIISDLSSTAIFSSSLLSDSTLAFKGSTSKEITADDSQGAEIRVAVLTVSDTVALGAGPDRSGPRAVSVVNSSSERLGGARVVATAVVPDDVSKIKDVLLRWSDIDKMDLILTLGGTGFTPRDVTPEATKGLLEKETPGLLHVMMQESLKVTPFGMLSRSAAGIRGSSLIINMPGNPNAAAECMAALLPALKHALKQIKGDKREKHPRHVPHAQAAPVDLWENSYKLASGGGGKEHGCSC
The following text describes a protein:
Function:
Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1.
Sequence:
MAPVADPKSKRYDRQIRIWGTHGQQRLESCCICLLNCGPTGSETLKNLVLGGIASFTIVDGGKVEARDLGNNFLVSASNLGEPRAKVVTELLQELNESVSGSYVEEVPEVIIADNPAFFNGFDLVIATQLREQDAVVLDGICRASGRARLLLVRSYGLVGYLRASLPEHRIVESKPDSQLDDLRLNAPWPELSSFAASFALEQLDEVAHAHVPYVVLLLQAAARWRAGHGGGLPATSADKAAFKAAVGGMRRTADGVPLPSENFDEALKAAFHVWTPYAIPSEVRALLADDAASLSGAGGGAGGAGGGGGGGGGLGPGSDDFWVLVAALRAFVEGEGGGCLPLEGSIPDMHATTDLYLRLAAVYRDKAERDTAAVEGHCRRLLAALGRPADAIAHDTVRSACRHARHLRCVRYRTLAEETAPGTARGGALAAALAAGGGGFLGPSDAPPGSSDAALYVLLRAADRFFAQTGRYPGDVTPGDPSDDIPLLRQAAQQVLIDTGVVPGGSGGSASGVGFNPRKSPDSSSGSGAAAAAAVSEDLIAEFCRFGAAELHVVAAFMGGVAAQEAIKLVTRQFVPLAGSLVYNAMSATTTVLEL
The following text describes a protein:
Function:
Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.
Sequence:
MEVPSLSKTIAWVLRHGAVKMDLKIRSNGYCSIKDLLEMDVKIGGGIPLSSFTVADVMSMVACDPKQRFSTIEEEDDQLYIRANQGHTMDAVQTAELLREIKSADEVPMCVHGTFRNNFRGIRKTGLKRMKRNHVHFATGLPQDGVISGMKSKCEVLIYLDLAKAMKDGMKFFMSENGVVLTEGFDGVVPREYFEKIMYITKEE
The following text describes a protein:
Function:
Predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration. Positively regulates T-cell trafficking to lymph-nodes via its association with ERM proteins (EZR, RDX and MSN). Negatively regulates Th2 cell differentiation and predisposes the differentiation of T-cells towards a Th1 lineage commitment. Promotes the expression of IFN-gamma by T-cells during T-cell receptor (TCR) activation of naive cells and induces the expression of IFN-gamma by CD4(+) T-cells and to a lesser extent by CD8(+) T-cells. Plays a role in preparing T-cells for cytokine sensing and differentiation into effector cells by inducing the expression of cytokine receptors IFNGR and IL4R, promoting IFNGR and IL4R signaling and by mediating the clustering of IFNGR with TCR. Acts as a major E-selectin ligand responsible for Th17 cell rolling on activated vasculature and recruitment during inflammation. Mediates Th17 cells, but not Th1 cells, adhesion to E-selectin. Acts as a T-cell counter-receptor for SIGLEC1; [CD43 cytoplasmic tail]: Protects cells from apoptotic signals, promoting cell survival.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. Cell projection, microvillus. Cell projection, uropodium. Note=Localizes to the uropodium and microvilli via its interaction with ERM proteins (EZR, RDX and MSN); [CD43 cytoplasmic tail]: Nucleus. Nucleus, PML body. Note=The sumoylated form localizes to the PML body.
Sequence:
WAQVVSQENLPNTMTMLPFTPNSESPSTSEALSTYSSIATVPVTEDPKESISPWGQTTAPASSIPLGTPELSSFFFTSAGASGNTPVPELTTSQEVSTEASLVLFPKSSGVASDPPVTITNPATSSAVASTSLETFKGTSAPPVTVTSSTMTSGPFVATTVSSETSGPPVTMATGSLGPSKETHGLSATIATSSGESSSVAGGTPVFSTKISTTSTPNPITTVPPRPGSSGMLLVSMLIALTVVLVLVALLLLWRQRQKRRTGALTLSRGGKRNGTVDAWAGPARVPDEEATTASGSGGNKSSGAPETDGSGQRPTLTTFFSRRKSRQGSVALEELKPGTGPNLKGEEEPLVGSEDEAVETPTSDGPQAKDGAAPQSL
The following text describes a protein:
Function:
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MAISCCMCGAQIEANAMNMCASCIASEVDVAEGIDTSCDLVQCRGCLRFQSKGKAQHFSSATGAWLACDWESTELMALCLKSIPGLSKAKLIDAGFIWTEPHSKRVKLRLTLQREVANHALVQNSCVATFVITSVKCPDCTKQYHNNTWRALVQIRQKAEHKRTFLRLEQEILKHDAHKDAIGITAVKEGMDFYFGTKSSAERFIHFLAAHVPMRSKSSSKLISENVHNATANLQLTYSIELSPICKDDLLILPRKLAQSCGNISDVTLCARTTSMVHVVDPVSGQRAELATDRYWKLPFLPLATSSDMVEFVVLDVEPVDSRDLRHVGPAPTSGRGRNSKFVVADVEVARASDFGVNDSTFHIRTHLGGVLSAGDTVKGYDLSSAIFGASQTYSLKEELPDLVLVRKVYPRENGKGHKGDRKLKTLGANRRGKVSKAETARLQHEMEVFTEEFLEEQEQAQQEGGDEEHESETDVQAPEETDVSASVEEQAAAMAQLNLP
The following text describes a protein:
Function:
Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCPRAPQSGLEGVF
The following text describes a protein:
Function:
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
Subcellular Localization:
Chromosome. Cytoplasm, cytoskeleton, spindle. Nucleus.
Sequence:
MKPVKSIFLKTYGKQMRKVSAWISPKDRKRAFDSTESDDDSVFESANPRRTRGKHKRVFRQEVRPAKKKAMQHLIESSYDEDSLMNENFNQPRGRKASVFSRTCGLAGHPVKRRANLRSKETSSSEENLPVGPCTLNKNKKLKRNNRLVSAPVLTKRKRHKITFTSDSEEENTAPKPKTKSVEAATDSNVHPLSAGRFVTRRRCAGLTRLTKATASGHSSSDDFTSERVFRPTRGRKAPVAFGLCSSESSMNDVGMSNCTANPLQEISLNASVERSLGPHLRKPIFCSTPSAGFFRKQGPSEAFPTCDQGSSPPSMSVSCIGASHEDLSFRQRVLPAQPGSVCGLHSEDRQQSKRDLDHIEEQSADLFVEPKESSCSEAKSVCGASRDVNLISVDSDGSSHFVSAAGGLEWLIEALKEECLSRRWTVQLDRLGLVLVSQLGDTTYSSCLERSSFVSSPQTASLRHLVGNDRTLNLASSASDLHETKASPSVDQEKSSDARATEKQSDDSIHPSDFSCNVIVSPHSPAEAKVAQGESLSKKRLVSLQKEQLKDITQPKDAALASAMLPSQDTNQPTDVKRAREVTAALSRADTTNGLKASAETPDSEKSASPLKKECLANRPVVPVKRIRLSELKETLQIKDAARESSDLSESDADRQAKTVLLLDGDENKSTSKANVRRRKVASGEKDSCRGATKHKQKPAGDKKKKSTTADTFNSTRKVCVSGMSVSRWKNKGGNFRSWAEQTGSSKIVDCSISELISAPWKQPQELVTNPENIFTPLKANLPPLLANLTPSTHTWSRIKAALSVHRKGMVQLTPTTLRLSETPRRNALANVSQDLFATPLRTPLPKHLQSQLLTQHSLVVCEEPDLSDAEKVYAECGQEHPLPWEECILPLRSKGCVKIGEGTFGEVFSTTNAAGETVALKIIPIEGSKKVNGEDQKTFGEILHEVIISKELSSLKEKQHNQTNGFIGLNDLHCVQGCYPSDFLKAWDAYDRRKGSENDRPDFFSKEQLFIILEFEFGGVDLENSNGTLASLGVAKSILHQVTAALAVAEQELHFEHRDLHWGNVLVKTTRKRKGSFLLNGETHHVETNGVLVRIIDYSLSRLEIDELTVSCDISNDEELFMGQGDYQFEIYRLMRQENGNDWSSYHPHSNVLWLHYLCSKLLSMKYRGSGRKGAKDTREALSRFHDNILQYNSATEALRNCAMFQ
The following text describes a protein:
Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Subcellular Localization:
Cell membrane. Cytoplasm, perinuclear region. Midbody, Midbody ring.
Sequence:
MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVLVKVVKVKKSDKGDFYKTQTVWLLRDLAVVDAKDAVKENPDFDLHFDKVYKWVASSIAEKNAFISCLWKLNQRYLRKKIDFANVSSQLLEELPKVAEESVPSGENQSVTGVDEEAAAEYQELNAREKQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMQLLDEALKEVDQIEGKLSSYEEMLQSVKEQMDQISESNHLIELSKTNGDTLLGEIEFLVNHMDLSKGHIKALQEADLSSSRGIEACTNAAEALLQCMNVVLHPGHDMLQAVKQQQQLFSDLREQFARRLASHLNNVFVQQMFPQLYSRFYYMSKAGHDQSSTLSAEMTLPNHHPFHRDLLRYAKLMEWLKNTEYVRYEGLTKNYMDYIVRLYEREIRDFFEVARNKMTGVTKEGKKFATLPRKETAVKQETESLHGSSGKLTGSTSSLNKLSVQSSASRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFNLSQHQSMSRTTMGETEESDGGVSSRTQTTGAQSEKEMIRQMMNYIFRCIEHELNSLIAFGDKIDSFNSLYMLVKMSHHVWTAENVDSASFLSTTLGNVLVTVKRNFDKCIINQIKQMEEVKVSKKSKVGILPFVSGFEEFAQLAESIFRVAERRGDLDKAYTKLIKGVFINVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKREAKQKYNDHLQSYVIVFLGHPLEKLNIFFEGVKARVAQGIGYDEVSYQLAFSKQELRKVIKDYPGKEVKKGLENLYRKVDKHLCEEENLLQVVWHSMQDEFIRQYKHFEGLIEKCYTGAGITMEFSIQDILEYFSSIAQSH
The following text describes a protein:
Function:
Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
Sequence:
MWAILSILVENKPGILFKVTHLFRARDFNIDSISVGVTENPEYSKMTITTFGDEKQIDQIVKQLDKMIDTVRVERLDEHKTVYRELSIFKIKLSNANDSMEVNKLANAYGGKVHDVKKDSIMVELTATPDQIKAFEELAKPFGILDVARTGVAALQRSGAE
The following text describes a protein:
Function:
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
Subcellular Localization:
Cytoplasm.
Sequence:
MSVLGACITPFKADLSIDFAALESVVRSQEHAGNGIILFGSTGEGLSLTYEEKLSILSFVSTLNLNVPIFVGVTATSVQETMSWIDFAQQWPIDGFLVPTPLYTRPGLNGQKAWFDRILSVSRKPIILYNNPIRTGVSLYPEVVKSFVSHPLCIGVKDSGGSAQACELFAESGLRVFCGDDNLWPDMRLSGASGVISVLANVWPELARDYVAQGRPIEAWKKVCSWLNLSTNPLGIKALMAAQKMIECDAVRPPLSIRDLQRRDELADILACRATLQTELLSVCRQ
The following text describes a protein:
Function:
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Subcellular Localization:
Cytoplasm.
Sequence:
MDHPASSKKNQHNGTVSSGVKGFVEQQISPGDERIVSSSSSTPVTHPLDPSLYYQNPTNLYPYGWNVAHSGYAQGINAWDGYPLYATSPEGLHVPQAVYNEDSSLMYQPGFAYNPYPSMMLEGQIPFSPAYYPQFGMHFSHSEFGVGNDPTSAYMIPFGGYGGGNLSGNQGANSLTYPQAMGILGPYDHDASQLPLHGNGISSSSSLGGYYPVGSYQSPSSTASYYGADNPVRLASDIGKRREKEYSSVPTTSDLYGNRGPRSFTRVKSKNGSGLSSSAGDATNDSSTAGPNPSLYNHSEFETDYKNARFFIVKSFSEDNVHRSIKYNVWASTPHGNKKLDTAYRDAEKMGGKCPIFLFFSVNASGQFCGVAEMVGPVDFEKDAAYWQQGKWNGQFPVKWHIVKDVPNNRFSHILLQNNDSKPVTHSRDSQEVKLRQGIEMLRIFKDYEAHTSILDDFSYYDERESQKVGEDGVTKEETFAVEQLSERLQAVTVEDGKEGEKEDLKEKT
The following text describes a protein:
Function:
Plays a role in cilia formation and/or maintenance. Plays a role in the regulation of cell morphology and cytoskeletal organization. Involved in DNA damage repair.
Sequence:
WWKLVYFQNSHARAAQHRRTVLSHHDAHSAVLQRLFFSTLCNGTAQSVTLRSEQLFSSPCVTRGSGFFHRFGGLWISQALRPALLRPGREEPTLAAAPPLATVGPGHEAEPGGRAGAGQGRRARWGPAAELGSHLTDISICRDLPNVEVITFSLNGISDLEPLNQCQNLSELYLRKNNIASLNELFYLKNLPRLRVLWLSENPCCGPDPHRYRMTVLRNLPSLQKLDNQAVTEEELSQALVDGEEITAPPARRSMENGCSASTESSAAESTMETESELLSFGLEETNKIREQLGMKPVPRDKFSSFSPQETDCSQKTRNNVLNAILLLTKELDAEGLEIVQQTVGRRLQAFRKRELQEE
The following text describes a protein:
Function:
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MFGYAVRRALRKSKTLRYGVPMLLLIVGGSFGLREFSQIRYDAVKIKIDPELEKKLKMNKVSLESEYEKIKDSTFDDWKNIRGPRPWEDPDLLQGRNPEILKTNKTT
The following text describes a protein:
Function:
Promotes megakaryocyte differentiation by up-regulating RUNX1 expression. Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene.
Sequence:
MSHGHSHGGSGCRCAAEREEPPEQRGLAYGLYLRIDLERLQCLNESREGSGRGVFKPWEERTDRSKFVESDADEELLFNIPFTGNVKLKGIIIMGEDDDSHPSEMRLYKNIPQMSFDDTDREPDQTFSLNRDLTGELEYATKISRFSNVYHLSIHISKNFGADTTKVFYIGLRGEWTELRRHEVTICNYEASANPADHRVHQVTPQTHFIS
The following text describes a protein:
Function:
Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
Subcellular Localization:
Cytoplasm.
Sequence:
MARALALSRSVQVCKSRLFTVASKSAITKRCLSNPIQYRSVSLFATTYAPSKDLNSRLHSEHIGDTALYLLLNPGLTSSVLFRADILAQSGKCPTLAALEAQKQQETEEASTATAMTMAQNVIEEEKEVKEPVVEIPAREVPGFELHKTLIRRLIPRNQQLDMPVDQTCHLYSHAGAVEQIEKEKELGIPHSRAPKERFMVIYTPHVSSKEELPYYHPLVRSMAFVYEFGYTGEFEGPENSIPRIAENPKGTMSIHFLPYENDVDSISARLERSLTKLIEVQIRTTKGRLDPCRPSTSSPYALIKDNVIPRNRVQDTYSRLKNKYAANLNERWIESTEPSKHVFEDLSIAAFLIELWRDLYGAVPGDEREQQKQQSSTSKVGSGQFPGFVDIACGNGVLVYILISEGYSGWGFDARRRKTWSIFPTDVQERLKEEIYIPKPFMDVLAAQNQGPIQNKNQDASMQSPLSEPQSGQSNGPNSGTSTSTSLSNLPKDTFIISNHADELTLWTPILSTLLNPANPPPFLAIPCCSHSLSGARHRFRPQSARPSATQNPQKQQGENGTHSQDEEGSSEDMKERKGEEKEKNPETGDLEQMRKDKLAAQNPH
The following text describes a protein:
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Subcellular Localization:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MSKMHVKLEIQSGRVKSLCFHDSRPWLLASFHTGEIIIYDYEVGVEIQRYNEFTVPVRTACFHPSLPLFAAGADDTCIKIFNYDEQRCIATFTEHLDYIRTVQFHPTKPFLVSASDDQTIRIWNYETNLCLTSISGHNHYVMSAFFHPTLPLVLSASLDDSVRVWDISSLFNDGQSSGGIFSITDAVMKFTQEEHTAGVNWAAWHPNKPMAVSCSDDESVKIWRIVETEMSLVATLRGHTGNISCACFMPNMDLVLSCSEDQTVRVWDSKRFVHLSKYKSEGNRFWCVAAHPVKPIFAAGHDNGLVIYSVTKNAPAYDTVDGNIYYYKENAIRAYNIKDESDGVTGYIKQRSSTSRQSPIDPKPTTVSYNPTHKVFLVGYPDRIEIVPANGKPGDDNQVIQGFNPVWIGRNQFVFQTDSQTQNISLREIGGSSTSTLTLKCRKIFPGPPGTIFGTDGETLFRYDIMRRSQISQTHLSNIKNIIMSPDRKHIGMLTSTDVIISDIDFNNITKVTEVVKTKSGVWFDSNVFVYSTRTHVKYLLINGEGGTLKSTPQTLYVAAISDKLYGLNIQDTVRKFPIDTLEIKFRLAIMENRIDAVVATLRSAKVCSTSIIDYLHKHGHPEIAVQFVHQPRAKFDLAMESGNLELGVDAATELADPVIWDRIADEAMAQGRFTVAEQAFKKSGNMERLAFLYLISGQTQKLNSLKVDDSLSLQRAIWSNDFKTEAILLHDVAPSIAYIAADGDDSLQSSIQVPDEIKDELKKFAKHEITSSPLKTVEKLEDWPTLYINRPKYVVTPGSQHDDDDDVENDDEENGWNFNEEAAEAKEENGEEDDDEENGWDMDDIQFDVTASPGQGAAAGFIVPSPGQSVSSQWMEGVEIAGQYAAAGEFGLALQVLSEQIALINAEPLKEHFVASYIASHVSIPALACAPPIISPLTAKFLKRKAPSPYFSIERMEKMIEEGSKLMTKGKFNAAKSIFLSLLQSIPIASVSTVEEQRKVIDAVEICRKYVIAAMLGIAQNSIKKPDKRKLEYLLYIYALKLDEKMQNIALNLAVNIATTLGCFKTALMFATDERTRKVIESKSQGNKTDAVKVDFTPVGNFEVCCNELVQIPIGEQKVSCPFCGATYKASHANELCSVCQLSKVGGIGTGLKINN
The following text describes a protein:
Function:
Catalyzes the ATP-dependent phosphorylation of thiamine to thiamine phosphate. Is involved in thiamine salvage.
Sequence:
MPFRSNNPITRDELLSRFFPQYHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGAVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRPLRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ
The following text describes a protein:
Function:
GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast.
Subcellular Localization:
Plastid, chloroplast outer membrane; Single-pass membrane protein. Cytoplasm. Note=Cycles between the cytoplasm and chloroplast, probably as a soluble preprotein receptor. The anchoring to the chloroplast outer membrane required the GTPase activity and GDP. May contain beta barrel transmembrane regions (Probable).
Sequence:
MKGFKDWVFALSNSMASSRPLLGSDPFFRDPHQEQDNHSQAPAAPQPVTLSEPPCSTSSDLEILPPLSQQQVPLESLYQSSIDLNGKKHNPLAKIGGLQVQFLRLVQRFGQSQNNILVSKVLYRVHLAMLIRAEESELKNVKLRQDRAKALAREQESSGIPELDFSLRILVLGKTGVGKSATINSIFGQPKSETDAFRPGTDRIEEVMGTVSGVKVTFIDTPGFHPLSSSSTRKNRKILLSIKRYVKKRPPDVVLYLDRLDMIDMRYSDFSLLQLITEIFGAAIWLNTILVMTHSAATTEGRNGQSVNYESYVGQRMDVVQHYIHQAVSDTKLENPVLLVENHPSCKKNLAGEYVLPNGVVWKPQFMFLCVCTKVLGDVQSLLRFRDSIGLGQPSSTRTASLPHLLSVFLRRRLSSGADETEKEIDKLLNLDLEEEDEYDQLPTIRILGKSRFEKLSKSQKKEYLDELDYRETLYLKKQLKEECRRRRDEKLVEEENLEDTEQRDQAAVPLPDMAGPDSFDSDFPAHRYRCVSAGDQWLVRPVYDPQGWDRDVGFDGINIETAAKINRNLFASATGQVSRDKQRFTIQSETNAAYTRNFREQTFSVAVDLQSSGEDLVYSFQGGTKLQTFKHNTTDVGVGLTSFGGKYYVGGKLEDTLLVGKRVKLTANAGQMRGSGQTANGGSFEACIRGRDYPVRNEQIGLTMTALSFKRELVLNYGLQTQFRPARGTNIDVNINMNNRKMGKINVKLNSSEHWEIALISALTMFKALVRRSKTEMTEENEEEKIVNFLVS