lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Sequence:
MVEEKRERAEEASESPQKSPRLDPLAGPGCSDAPASPTESSDEWPSSGEVEAGISSDSTGDSMDDSGRCDHIRFDLDMVVHDLKVANQVLKEPRKCQHRNCKTTWEGASEDDQGMMKCIDCSYFFCSGWPVDRDDPQGHARWHAGEHQHWVAQWCDEPNLGYCFMCARPMRLSDWSEDDYAVAARNEKDQQMPGDSVAKDGWGSVSGIAKDERQRVPRIAMDDVASGYAIGDGHVIKGMPNHGQTCFMNATLQCLLALGKLRTKIRSPDAHLGSIGLHLQQLFKETRISNDARGMLDPCMILAAVRERYPNRFEAWKMEDSHEFLLSLFNAVNAEVEVENGRHVLEGGEVFPTFHVSLFGGQLFETTSCQRCPPKDPKTVDFGELYLSLPEKDPPARSVASPPRNKSHGSQTDKSDGDNKIQTTAEGSTSPISGSGLGDGAMEKTPKPLQVDSSEVKDVVHGHMQTQKNDVPQEINEVPIEILDFIPDLFDDTEGMEEATIDSRNPEDKETTYSVKVTTKEKEEAQSSDIVHDEAGHMNSLVSIEDCLELFARRVLERCENCSKVAEQIMASTNINTTVDRDQTELSDRKTCPSERSSDCNSLSVESPSRQPYRSDVHHQVILSENITTEEITSGASCGEKDSASCSTASEKAEIDQGVQEAGLPADKQTDLLSAQDSPDTSTQNQGCAKQAMLDDHIAQQMEENQSEQKDGNSCAIQTQLINKLPAVLIIPFKRYSNDLSKLRGHVSFKEILHLGPFMDPRSEDKDNCSYRLVGVIEHEGHQINGGHYIAYVRGAGHNHQSSGSSSWVRASDLDIKEVSLEKVLGREAYMLFYERMED
The following text describes a protein:
Function:
Regulates the size of the shoot meristem by modulating the CLV3-WUS feedback loop. Can repress WUS but is under negative control by CLV3.
Sequence:
MATVVYQSYFESQHFEPRALRLRLSSHTNPQLSTPLKSHFQNSSIAPQDNPITINAASLPSSSPNPSSNSDTNSGSWSFLESLSNSSSNDKEKKTLPLFQSPSSRRTLSDESLALCTESLGSETGSDIIHEDMFSISSELQTMETRTTSTTSNPSRQDRKRNTMASLPPPLTSMIGFDCIEVKSHRENGRLVMMATRPPPRNRCLQDRSNGCVRLAILIDSDDHIETETKEEKEEEEEETIETVRDNEEEIPEYKEEEEEKEEEIKVKGVEKVQRSRRCIEGDRENRGFLNWESLCVATS
The following text describes a protein:
Function:
Rho GTPase-activating protein involved in the signal transduction pathway.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MKSSKKTLTNFWKDPSTGNLVSPSPSSINGGASSSGGGGSTISPTKLAKEGPVFGVPLNDIFKRNSTNVHNVPNVIWHISSNIRQSAMDVEGLFRIPGSNTTLQLLKKNYNEGKIGTKDDLNDKCDDIHTQASLLKLFIRELPDPLFTFSLYDSFIKSHGSKDKSIRVGSLKMLLGQLPIAHFSLLKFLAELLREVSTHSVNNRMTSTNLAIVFGPTVMRPQTEDIVKMIEDARHINGIFLLIIDEYEFLFNVMYINRNRNININIYLWKSKKNPKISFQFWNFLFFILVFFFEQPTFANNPSPNTSRNNLNSSVRQSPNKGFVSSNPNRKASKFEFSVVDDVENNSNDINNNIKLNTNNNNNSGKSQQQLLQQLQMQQLLSISPNSSVIGINQQNANNNSGNNNNNNNNNNSSNNQNKFSILLPVNNHPQPTLLAPSSPSSSIYGRNNSNGINNGATSPLPPASPRSSLTLLDMNHLNCGVNDYSGGYNNNINNSIGNNELIRGLIKKTCSILFDKELTSLTDGFEITKDETFIPAFDTSNINNHHSSPTSNSVNNNNSNNNNNNNNSSNNNNNTLNSDISQISPRFSRANEISSASNSSTSSPQLRSLLKSHVNNNLNNLNNLPNLLGNLQAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLKNQSDENNNVTINNSNNNNNTPTSPVLNIINNAPITIPSSPPLNTVTSNLSPSTPYNESNNNNINNNNNNNNNNNNNNNNNNNNNNNNNINSNSNNNPLDIAFSHLEKVRKEGKRNSDINLMSIDELNEEKSAIKKELRDFDTNFKRQYGQLPRKNDKEIMRPLYIRYREVKSLIDLKSPQSVTSTLSNSSSLPSTPISLSSSNSLNKSQPSNNNNNNNNNNNNNNNANNTNTNNSNNNNNNNNNNNNNNINNNSNTANMSNSTSTLSSSGQHQLERANSSSSITSAAGIGGGSNSKSSTSPPNVVSPYISPSTSFNSLTELSNHQNNNNSNNNNNNNNNIDTSAPMIVDSHQYNSGNSNSNSNSNSNSNSSSKSSSPNITDFTKLSLNELKDRYIKVKGEKRSLQIDLHRYQSEFTKKHGRKVQFVEDRVPVQAEYEKYKELKIEIVALENILVLINNNHNHNHNHNHNHNNNNNNNNNNNNNNNNNHTTLYHL
The following text describes a protein:
Function:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MEVSLRTISGVTYKQAVEPTTTIAELKVLVSEKANVAPEGIKLIYSAKFLDDSKTIAESNIQPGQAIIMHVQSSKNAKQPQKKSSEKRKSPKKESPIKVQEAAAPAPTQPKEEATQKPEQPGHSMVAPLPELEAKHQLVDPPNFNALVQTLTEMGFSEGDAAHALRAAVYNPDRAAEFLLTNYIPEMPQLYDPNDLANEEEDYDDDDNSDEEDDEQASTLQFLRQLHQNPELLPIYLKDLADNNPAVAPLIRNDPASFLVSLGVNPSEFDLSSLKHKSEFETLMEKFTEEEQKAIHRLEKLGFDTTDVIQVFEACDRDENLTKSCLEQMK
The following text describes a protein:
Function:
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in DNA replication and DNA damage response and also in cell wall function.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Sequence:
MSELTEAEKRRLLRERRQKKFSNGGASSRLNKITGQASSHLNAESPLDAPSAAKTTPPASVHSATPDIKEDSNVAPQLDLLKQLAAMQGQGTGKSTPQDSSTPDLLSLLSSMNTGMPSAEGTPSFGQAAPAAPINQAALDYHDYLLNRLKAWTILVKWVFFLLPYLYLITRPNSSVWPAYAFTQSAWFAPLRNPSNFTRIFATFEFLSISIYYQLLKNVEHKSKIKNLQDTNKLVKLVSLVPEGVIPVANLKGKLITLLQYWDLLSMLITDISFVLIVLGLLTYL
The following text describes a protein:
Function:
Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent pre-initiation complex (PIC).
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MAAPLLHTRLSGDVTAAASATLSASRTGLSDMLALESDFFNSPPKKTVRFGGTVTEVLLKYKKGETNDLELLKNQLSDPDIKDDQIINWLLEFRSSVMYLTKDFEQLINIILRLPWLNRSQRVVEEYLAFLGNLVSAQTVFLRPCLSMIASHFVPPRVIVKEGGIDVSDSDDEDDNLPAIFDTCHRALQIITRYVPSTPWFLMPILVEKFPFVRKSERTLECYVHNLLRISLYFPTLRREILELVIEKLLKLDVSVSRQDIEDAEEKAAQTCGGTDTTEGLFNMDEDEDTDPEKKADQEQPNQMAHPTAERLDVLLCLLLSYIEDVCRVHGKIDNNKTKDLYRDLISIFDKLLLPTHASCHVQFFMFFLCSFKLGFAEAFLEHLWKKLQDPNNPAIIRQAAANYIGSFLARAKFIPLITVKTCLDLLVNWLHMYLTNQDSGTKAFCDVALHGPFYSACQAVFYTVVFRHKQLLSGNLKQGLQYLQSLNFERIVLSQLNPLKICLPQVVNFFAAITNKYQLVFCYTIMERNSRQMLPVIRSTAGGDSVQTCTNPLDTFFPFDPCVLKRSKKFIDPIYQIWEDGSAEELQEFKKSTKKEVVEDEDDDFLKGEVPQSDTVTGLTPSSFDTHFQSPSSSVGSPPVLYIPGQSPLLTRIYD
The following text describes a protein:
Function:
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.
Subcellular Localization:
Lysosome. Secreted. Apical cell membrane; Peripheral membrane protein; Extracellular side. Note=Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells.
Sequence:
MWVFKFLLLPVVSFALSPEETLDTQWELWKKTHGKQYNSKVDEISRRLIWEKNLKKISVHNLEASLGAHTYELAMNHLGDMTSEEVVQKMTGLRVPPSRSFSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVSENYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPVSVSIDASLTSFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGNKYWIIKNSWGESWGNKGYVLLARNKNNACGITNLASFPKM
The following text describes a protein:
Function:
Converts acetoacetate to acetoacetyl-CoA in the cytosol (By similarity). Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids (By similarity).
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MSKEERPGREEILECQVMWEPDSKKNTQMDRFRAAVGAACGLALESYDDLYHWSVESYSDFWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRLNYAENLLRHKENDRVALYIAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIPYVSSRENIDLSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWGESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQIIAGKAVEQGGAFSNPETLDLYRDIPELQGF
The following text describes a protein:
Function:
Plays a role in electron transport. Utilizes the bis-histidyl hexacoordinated complex with iron to transfer electrons to cytochrome c and molecular oxygen. Plays a regulatory role in the periodicity of the defecation cycle under oxidative stress conditions. Not involved in imparting protection against general conditions of oxidative stress. May participate in redox reactions under anaerobic conditions.
Miscellaneous:
MISCELLANEOUS: Binds carbon monoxide (CO).
Subcellular Localization:
Cytoplasm. Nucleus lamina. Cell membrane. Note=Transported to the nucleus by myristoylation of the N-terminal glycine.
Sequence:
MGSSTSTPAPPPKKNKPEGRKADNQILNSYQKSIVRNAWRHMSQKGPSNCGSTITRRMMARKSTIGDILDRSTLDYHNLQIVEFLQKVMQSLDEPDKISKLCQEIGQKHAKYRRSKGMKIDYWDKLGEAITETIREYQGWKIHRESLRAATVLVSYVVDQLRFGYSRGLHVQGSRETKEDDEE
The following text describes a protein:
Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence:
MDSQDCTCAAGESCSCAGSCKCKNCRCRTCRKSCCSCCPATCSNCAKGCVCKEPASSKCSCCH
The following text describes a protein:
Function:
Channel protein for glycerol. Has a role in both glycerol influx and efflux. Plays a role in osmoregulation: under osmotic stress the channel is apparently closed to allow accumulation of glycerol in the cell under hyperosmotic conditions.
Miscellaneous:
MISCELLANEOUS: Present with 907 molecules/cell in log phase SD medium.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Domain:
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro/Leu-Ala/Ser (NPA).
Sequence:
MSNPQKALNDFLSSESVHTHDSSRKQSNKQSSDEGRSSSQPSHHHSGGTNNNNNNNNNNNNSNNNNNGNDGGNDDDYDYEMQDYRPSPQSARPTPTYVPQYSVESGTAFPIQEVIPSAYINTQDINHKDNGPPSASSNRAFRPRGQTTVSANVLNIEDFYKNADDAHTIPESHLSRRRSRSRATSNAGHSANTGATNGRTTGAQTNMESNESPRNVPIMVKPKTLYQNPQTPTVLPSTYHPINKWSSVKNTYLKEFLAEFMGTMVMIIFGSAVVCQVNVAGKIQQDNFNVALDNLNVTGSSAETIDAMKSLTSLVSSVAGGTFDDVALGWAAAVVMGYFCAGGSAISGAHLNPSITLANLVYRGFPLKKVPYYFAGQLIGAFTGALILFIWYKRVLQEAYSDWWMNESVAGMFCVFPKPYLSSGRQFFSEFLCGAMLQAGTFALTDPYTCLSSDVFPLMMFILIFIINASMAYQTGTAMNLARDLGPRLALYAVGFDHKMLWVHHHHFFWVPMVGPFIGALMGGLVYDVCIYQGHESPVNWSLPVYKEMIMRAWFRRPGWKKRNRARRTSDLSDFSYNNDDDEEFGERMALQKTKTKSSISDNENEAGEKKVQFKSVQRGKRTFGGIPTILEEEDSIETASLGATTTDSIGLSDTSSEDSHYGNAKKVT
The following text describes a protein:
Function:
Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451 (By similarity). Can catalyze the formation of poly-SUMO chains (By similarity). Essential for nuclear architecture and chromosome segregation (By similarity). Necessary for sumoylation of FOXL2 and KAT5 (By similarity). Sumoylates p53/TP53 at 'Lys-386' (By similarity). Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity (By similarity).
Subcellular Localization:
Nucleus. Cytoplasm. Note=Mainly nuclear (By similarity). In spermatocytes, localizes in synaptonemal complexes (By similarity). Recruited by BCL11A into the nuclear body (By similarity).
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITINQLFIGIQELLNEPNIQEPAQAEAYTIYCQNRVEYEKRFRAQAKKFCPS
The following text describes a protein:
Function:
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
Subcellular Localization:
Cytoplasm. Dynein axonemal particle.
Sequence:
MASNDKEFRMTKEEVDKLEKAMKNEEFRKLLVEYAQEISDPENKKRYEEEIRQMENERGMDVKFVNPEEGFVVKTTRETDGIKAFVNICYNQHIEKATFRMAEKGDGTERKKGQQWSIPYSLAQPRDDFDRAGKKCVTFDVVFHPDTYKKCTKMPQFKKMVIETALEGIERQLNIKLNKKNLKFPKMKFKGMKQATVIRNKSNENSFKKPNEGITIGDKTIPYPYADQPTCANKQAHKSRTPGQITSKVKDNNADTRDPRNPEYTILHRGIIDFQNFTNARDSCTSTRPKELVIRIDLPDLALNHCKYRYSAFSRCCQFFLDICHITLPYPIDENKGSAKFDKSKQQLVVTLLVLPPPPPPQVTTFPDPADEEAGQGDAAQQDPEGSSQAQETDGKGQTGKRVQVDGNPGSTSNDLEKDASVADNSSEDKMEAHENMQGVNDAADENMQDVNDAADDNMQGVNDAADENMQGVNDAADENVLGVNDVDDAQAVNHASGINFELPDLSFPFFKCPSYSYHQDDDTITFVIHESGVTLNNVSLGFLENMCYISFPSVMTPHGQPGQDFALYVTFNEGQNLDPDLCDINVAENSLVLTLQKDDSCKGLWDTFKAGPSEENLEERYFVTESNLEAMMEEIAAQDPWAKQSSFTTDLEVTAFSEESLSVKLESKPLGAQIEPPPDGHVVPQQGMPLVTERELGNLTSKLQDSSLASPDEGVVSDISAKGKKVAFSSSLAQSLITEDENREQSNSKMCRSDSVDSASSDRSDSDIYTNGVRMRKSCLRRTSSTCSEDSEEFDYSGPLSPESPGKKNVRFNLNHNVRVFSNKKDKKRWKMGQRLKEQKEGRGVGSVSPSGSVSSNGSIPESGEGVKPKVNGKSRKDSESSADEEWTCKQTSSSLSNTLIFELDD
The following text describes a protein:
Function:
Probable serine/threonine kinase. Seems to play a central role in cell-cycle regulation by transmitting DNA damage signals to downstream effectors of cell-cycle progression. May recognize the substrate consensus sequence [ST]-Q and phosphorylate histone variant H2AX to form H2AXS139ph at sites of DNA damage, thereby regulating DNA damage response mechanism.
Subcellular Localization:
Nucleus.
Sequence:
MSNFAGHIKELRALIAGSSSSAAAPASAHYEAKLREVLPSLLRDNVLPAPTATEMETKVVLRLLNYTAPRFPGVFSNGRPAEVIRVIGRILPLFAEPDYQSIIFEPVWSLLSLLRTGDREAYRQFFLDAMVAVEDLQYVASKHTESGCLLKCFCGSFSDILESTAIFSDLPERFQPKNGPGVLIDLSGDMRWCSFATSLIRLINKCLTDGTLHVEGIVTMPFVSAACSILCYGDESLHKVCFDFARIVATVMTVEILPTETIIRSITSILSQDVNELSSIRDPDYDLSMGACLNALHSLCPGYIVESTAADIVNVFTRAVQISRSSELQAAMCNAYMRIVEVCPPQVWKPEILLKLLYLPKPYDKVTECIRLVVDKFGQSLVSVDASDDRGSFQEKSEVFELPKVGQKRVAQNQENTLYKRQKMSESRSTIGSFMAKFSPAGIGHELAKDYAYDLQLSLNSRIKFLSPDNHNAYPLEPDIAIQVLSLLSLSFCVNPKTSLFISISKQVLSWIPWICKQATEKCFFSFDMLLYFKALQTVMLLRSFHPGDSKLFEDEARLICDRSEDLDYPLYVDLISLLKRVWSDGHVSTQACLDKLKCLVVQVIAKIGNRLNIDCDLELLELAIHSESVEVQNEALMSLPIIVLYSGPTMLGVMFKKLELFGDLGSDKVWKCVAFSLGFLSCLNGTTDVTDKAGNSCKLFMDKDSKQPVSTLDLLLKGFWCPHCDNRTVNTKEQISIVDMAVLETENVALKHNILKAHTLFFKFLYAQTSKECIISMVEVLPRVLRHSSKEVLLEMKIKWVNCIDFLLLNGMKDVRDAFSLVVCCFLETRVMDILFSDELGMEGGTKELKFMDKIKQAFAEAEDSHVLLTLLESTATIMQASDTQGEVFFCSFVLLIAQLDNHDPIVRKTASRLLHRCCTYSFKGGIELFLSNNFRVRDDLYDYLSSRLLNHPVVINEFAEAVLGIKTEELIRRMVPSVIPKLIVSHPDNDQAVITLHELANHLNTELVPLIVNSLPKVLSFALFYEDGQHLPSVLQFYHTETGSDSKEIFAAALPTLLDEIICFPGESDHIETDRRTTRISPTIQNIARILTGNDTLPEFLKNDFVRLLNSIDKKMLHSDDLKLQKQALQRIRKLVEMMGPYLSTHAPKIMVLLIFATDKEALQMDGLDVLHFFIKQLAEVSSTSIKYVMSQVVAAFIPSLEKCRECPSVHLRKIVEILEELVVKNSKLLKQHIRELPLLPSLPSLSEVNKIIQEARGSMTLQDHLKDAVDGLNHESLNVRYMVACELSKLFKVKREDVTALIIGEDTSDLDVISALIMALLKGCAEESRTMVGQRLKLVCADCLGALGAVDPAKFKVISCERFKIECSDDDLIFELIHKHLARAFRAASDTTVQDSAALAIQELLKLAGCQSLPKEDNGEDSSSCEMSRRGQKLWGRFSSYVKEIIAPCLTSRFHLPSVNDAALLGPIYRPTMSFRRWIYYWIRKLTSHATGSRYGIFSACRGIVRHDMPTALYLLPYLVLNAVCYGTPEARQSITDEILSVLNAAASESSGAIVQGVTGGQSEVCVQAIFTLLDNLGQWVDDLKQEIALSQSNNAMAGRQAGKLNEESCSNNGQDQLLVQCSNVAELLAAIPKVTLAKTSFRCQAHARALAYFESHVREKSGSSNPAAECSGTFSDDDISFLMEIYGGLDEPDGLLGLANLRNSSSLQDQLIINEKAGNWAEVLTLCEHALQMEPDSVHRHCDVLNCLLNMCHLQAMIAHVDGLVGRIPQYKKTWCMQGVQAAWRLGRWDLMDEYLPEADKGLVYSSTENSASFDIGLAKIFKAMTTKDQFMVAEKIAQSKQALLVPLAAAGMDSYMRAYPYIVKLHMLCELEDFNSLLGDESFLDKSFSADDPSFLKLTKDWDNRLKCTQSSLWAREPLLAFRRMVYNLSHMNSQVGNCWLQYAKLCRLAGHYETAHRAILEADASGAPNVHMEKAKHLWNIRKSDSAIAELQQTLLNMPAEVLGNAVLSSLSSLSLALPNAPISATQASKENPDVSKTLLLYTRWIHNTGQKQSEEIKTLYSRVTELRPKWEKGFFCMAKFLDDLLVDARKRQEDKKFTGGVGSVTPGSAGSASAPAKERPWWELVPTVLLCYAKGLHKGHKNLFQALPRLLTVWFEFGNIYIQEGRSAEMKVVHDRMLAVVRGCSKDLPTYQWLTVLSQLISRICHQNGELVRVVRYIIQVVLQAYPQQALWMMAAVSKSTVSARREAAGQILKLAKKGVGKRSDHVALFNQFPSLIEHLIKLCFHPGQPKARSINISTEFSSLKRMMPLGIILPVQQALTVTLPSYDSNMSGQSTFHPFSISEHPTIAGIADDAEILSSLQKPKKVVFLGSDGVARPFLCKPKDDLRKDARMMEFNAVINRLLSKVPESRRRKLYIRTFAVVPLTEDCGLVEWVPNTRGLRHILQDIYITCGKYDRMKTNSQMKRIYDVCHASKIPEDEMMKTKILPLFPPVFHKWFLTTFSEPAAWFRARVAYAHTAAVWSMVGHIVGLGDRHGENILIDATTGDCVHVDFSCLFDKGLQLEKPEVVPFRLTQNMIDGLGIAGYEGVFLKVCEITLSVLRGHKEALMTVLETFIHDPLVEWTKAHKSSGGEVRNPQAQRAIANITARLQGVVVGVNAAPSLPLSVEGQARRLIAEAVSHKNLGKMYIWWMPWF
The following text describes a protein:
Function:
Vesicle trafficking protein that functions in the secretory pathway.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Sequence:
MSVIDILFRVDDICQKYDKYDIDKQRELNAYGDDLFARLYAAVESSIQSALNKSEVASTEKNRASAAALNAEVRRTKGRLMDELPKLRKLVHKKVKGLTKEDMAIRQDLVLALPERIQAIPDGISGAAVQTAGWTATSSQPHIKFDSSEGHLDSDYFQQSEESSQFRQEYEMRRTKQDEGLDIISEGLETLKDLAQDMNEEIDRQVPLMDEIDRKVDRAAADVRNTNVRLKKTLTEIRSSRNFCIDIVLLCVLLGIVLYLYNALR
The following text describes a protein:
Function:
Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Sequence:
MMSSLHQDHQTLRHRKLTDEDDDDGEGRSVVKLQSKWNTVHLSGVCVLLTVSLIKLLDACHSSSSSWVLLSSGSSIWDWWSVCVLLSFTVLQVALYYLPVGQETEGKIGPNGKPLKYKLNGLCAFSVTLLLLLGVWFCGVLRAAAVSERVFSLISAGAAVALMLSLMLFLSPPHTHSCTHVHYDHTAKPLLQFVLGQKMDPRLGLIDVKHFVMVRIGFIGWAVMNVLYLLSAVEMEGSVSLSLLLVVLFQLIYILDFLIDEGSVLTTKEFTEEPIGFIMILGEFIWIPFFSNLPVYFLLQRPNHIHFLSAVPICLLFGVGFLIYYLSNEQKDGFRKNPDDPAYAGLSTIRSPSGKSLLVSGWFGWVRHPNYLGDVMMMLAWCLPCGFTSVLPYLPALQCFHLLRQRANEIEESCLKKHGDAWREYCRRVPYKLLPYIY
The following text describes a protein:
Function:
Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria.
Subcellular Localization:
Mitochondrion membrane; Multi-pass membrane protein.
Sequence:
MSSNKLPTSKYDLSTYWGRVRHAMDITDPRTLLSTSQDLNSAVKTLEDYGAGKIAQLDETVWHAKKIVDSTLHPDTKEPVFLPFRMSCFVLTNLVVTAGMLQPNLGTAGTVFWQWMNQSVNVAFNSANANKSTQLTLPQMTKSYIYAVSASCGVAIGLNKIVPRMNFLSSSSKAVLGRLTPFAAVASAGVLNVFLMRGEELRQGIDVFDKEGESLGKSKKAAFYAVGETALSRVINASPIMVIPPLVLMRLQKQNWLRTRPKLTIPVNLGLITLTSLIALPLAIGVFPAREKISPFKLEPQFHHLKDKSDQPIVEVEFNRGL
The following text describes a protein:
Function:
Scorpion venom phospholipase A2 (PLA2) that is lethal to crickets and crustaceae. Causes inflammation in mice and lysis of human erythrocytes. Has a mild anticoagulant effect on human platelets. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Subcellular Localization:
Secreted.
Sequence:
MVKRVSKEEMDALERSCSQPFEEERFLIVSGTKWCGNNNIAANYSDLGFLEADKCCRDHDHCDHIASGETKYGLENKGLFTILNCDCDEAFDHCLKEISNNVTTDIRQKGGAENVWRFYFQWYNANCYRLYCKDEKSARDEACTNQYAVVKKNFTVQ
The following text describes a protein:
Function:
Catalyzes the conversion of methylthioalkyl glucosinolates of any chain length into methylsulfinylalkyl glucosinolates.
Sequence:
MASSSSKKVCVVGAGVSGLVSARELRREGHDVTVMEQSGGIGGQWLYDPRTDAGDPLGVAGAQSSIYASLRLNTPRETTSLSDFPFFPTNDGTGGDARRYPLHGEFLSYIRDFCGAFGLMDAVRLNTKVLHVGPLAPCGRGRGHDGAVTRWMVRWSRHGDCEGQVVTAEEVFDAVVVAVGQNTQPRLPTINGMDKWSRRQLHSHSYRSPDSFDDQVVVVVGCHPSGTDIALELCTVAREVHISVKSMDAAAVVPGMRRAVSRHDNLHLHLQIDCLCEDGQVMFADGSCVVADSIIYCTGYDFSFPFLDTGGLVTVDDNRVGPLFEHTFPPSLSFVGVPRMVVVPRFYEAQARWVAQVLSGRRPPLPPEEEMLRAAEYHHRAREEAGVPRRQSHNIFFDVDYMDEFGAKHCGFPRLPEWKKELLRSSVARLRDATESYRDDYRDSGLVREGLQAQGWLTGRPPPPPDTRVENES
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage. Exhibits GTPase and E3 ubiquitin-protein ligase activities. Regulates dendritic spine density and synaptic neurotransmission; its ability to hydrolyze GTP is involved in the maintenance of dendritic spine density.
Subcellular Localization:
Cell projection, neuron projection. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Endosome. Membrane; Multi-pass membrane protein. Membrane; Peripheral membrane protein. Nucleus, nuclear body. Nucleus, nucleoplasm. Perikaryon. Postsynaptic density.
Sequence:
MEKSPPIASTINLEEDLTCSICLDLLEDPTSLECAHNFCSTCITDYCSTETQDAQCSAQPRCPECRSPFQRDQCVPDTRLRSLVQKFKSRQQKMLTFFQEAKEPKALKLVDCCPSEGPILNIDALNHCLRNPKVQDTPVCLITVLGEQRTGKSFLLNQMLLALKAMESGQDSWRPQGGEDLQGFQWGGGSDTITKGLWIWNKPFLLKKNEEKVAVFLLDIEGSMALDECKESNVKLSALTMLLSSYQILNVFRILKEADLEYLEMFLHVAETIGEICGMEAVQHLDILVRDWGYSEEFGWAPGKAYMNDIIQKQKRKHPKVWKMLQEARTQCYLLPFAGKNMATKKGGNTADMDAEFCSSLHAYVIHVLESANNHAKRGQKGPLTGNQLATAIEVLSDLMKHEKFGFSSPVEMATDFKNRMLQKIKEFEEIMKKEKAIQQHNLDLKQNKFKEFEEFLGKQNEATKPLFSALRIRPNTMKACLAKERDSILASFSEAYIGKDQRWAVETLQEKIQAKEETFLKAYFKRYCGHVAAAGGTAAGVLALVGAGVGAGVAAAVVAAEAVPLMSAGIAGAVGAGVGAGVGAGVGTGVGVGVGQSSRRAEQQNEEEEELLDAEEL
The following text describes a protein:
Function:
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Subcellular Localization:
Nucleus.
Sequence:
MVRLKTRYLVVEASGGRKLAVKKEDIAALIRESITKSYGDFGAGLAQLAVIRCAREMCKMVETSLVFVTDVHNQDVSIRVARVCGSSRTCREHLLKFSLERAKTLNLYATQPNFDEEVQAEIARVDPQ
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSNSGPKSGKATERASFVNLLSQYLKEKRNIGDISVGMTSKPEAKGLEASRQQAMPMNFFPNMDNPSDSSRPNLVASTSNVKPSDFFPEIANFGASSSKEDSTNKTDFRKPATVEPKSAQLTIFFGGQVLVYNDFPAEKVKEIMALASQGCSTACAGVVTDSGMEKVNSNMDKINSSNSDIPDLNIASTTGNSPDQDPSVERRQYGGSDLRIARRNSLHKFFEKRKDRAAARAPYQVNNQRGSPPPPKPDESKSSHEAGQSSKEASRDLDLKL
The following text describes a protein:
Function:
May be involved in countering the first line of host defense mechanisms. Impairs the leukocyte response to FPRL1 agonists by binding directly to host FPRL1. Exerts, in vitro, anti-inflammatory activity by inhibiting calcium mobilization and cell migration toward chemoattractants.
Subcellular Localization:
Secreted.
Sequence:
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDDGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY
The following text describes a protein:
Function:
May be involved in mRNA splicing.
Sequence:
MGERKGVNKYYPPDFNPEKHGSLNRYHNSHPLRERARKLSQGILIIRFEMPYNIWCDGCKNHIGMGVRYNAEKKKVGNYYTTPIYRFRMKCHLCVNYIEMQTDPANCDYVIVSGAQRKEERWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSAWKDDFALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYEDKQKLKRTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDVPESPQHAADTPKSGEPRVPEEAAQDRPMFPGDCPPETPETPKCSSPRGQEGSRQDKPLSPAGSSQEATDTPDTRHPCSLGSSLVADYSDSESE
The following text describes a protein:
Function:
Hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors.
Subcellular Localization:
Membrane; Single-pass type II membrane protein.
Sequence:
MERAEEPVVYQKLLPWEPSLESEEEVEEEETSEALVLNPRRHQDSSRNKAGGLPGTWARVVAALLLLAVGCSLAVRQLQNQGRSTGSLGSVAPPPGGHSHGPGVYHHGAIISPAGRELLVAGGNVVDAGVGAALCLAVVHPHATGLGAMFWGLFHDSSSGNSTALTSGPAQTLAPGLGLPAALPTLHLLHARFGRLPWPRLLVGPTTLAQEGFLVDTPLARALVARGTEGLCPLLCHADGTPLGAGARATNPQLAAVLRSAALAPTSDLAGDALLSLLAGDLGVEVPSAVPRPTLEPAEQLPVPQGILFTTPSPSAGPELLALLEAALRSGAPIPDPCPPFLQTAVSPESSALAAVDSSGSVLLLTSSLNCSFGSAHLSPSTGVLLSNLVAKSTTSAWACPLILRGSLDDTEADVLGLVASGTPDVARAMTHTLLRHLAARPPTQAQHQHQGQQEPTEHPSTCGQGTLLQVAAHTEHAHVSSVPHACCPFQGF
The following text describes a protein:
Function:
As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. Acts as a light chain for MYO7B and is required for efficient targeting of the IMAC to the tips of border brush microvilli.
Subcellular Localization:
Cell projection, microvillus.
Sequence:
KYKFQINQYLLHKYKECFSLYDKQQRGKIKATDLLTVMRCLGASPTPVEAQRHLQTHKIDKNGELDFSTFLTIMHMQMKQEDPKKEILLAMLMADKEKKGYIMASELRSKLMKLGEKLTHKEVDDLFKEADIEPNGKVKYDEFIHKVTIPVQDY
The following text describes a protein:
Function:
In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.
Subcellular Localization:
Cytoplasm.
Sequence:
MNLFLTESLEDYILSIYELQSRIVRIKDIARLKKVKLPSVVNAIKILSDMGLVEHEKYGYVTLTDYGIEVAQELYRRRKLLFRFFTEILGVDENTALQDSHRIEHDLSPKSLEKLTEFTERFIKSRKEEKDMPLTLKDLKVGEEGKIVELRGGGGIISRLLSMGAVPGTIVKVEKIAPLGDPIEILILGYHLSLRKEEAEKILVERI
The following text describes a protein:
Function:
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
Sequence:
MSVKKQLERLSELGAYYHKNGWMPGTAGNLSIRIPEESGFWVSGSGLDKNLLNKRNFLYVDLESGKPVDSKNIKATKGLKPSAETSIHRAVYRALDGVGCGLHVHTLESNLICANTSKNEPIVLFELPAIEILKAYGIWEENPKVYVPIIYNFPNVQDISDCLEKYLKEYRPHVPFCIIEKHGITVWGKDAVQANRNLEATDFILKYMTSWKSFSYSGEPRKLSVSDVLGQDRREIFSVEFPVYPATFY