lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Putative transcription factor. Required for leg joint formation, acting downstream of Notch to pattern the leg tarsal segments. Functions in the terminal pathway during embryogenesis, acting downstream of tll in the posterior of the embryo. Acts in a hierarchy downstream of drm and lin during foregut and hindgut patterning and morphogenesis. Involved in cell rearrangement during elongation of the embryonic hindgut. Regulates expression of hindgut patterning genes to establish the small intestine region of the embryonic hindgut. Required in the foregut for spatially localized gene expression and morphogenesis of the proventriculus.
Subcellular Localization:
Nucleus.
Sequence:
MPTESSSSEISGGGGGAIPMLRPSRMDQFMNSMAAAAAAVGGGGLPGAADRNGGSGGSDGGSQNGNGDSRNSSASRISAYETQLAYQQHLAGLHGPPPPPPPSHHREISAFVPVLPTGKVRPGSNSNYEIIAMMADKRKELALREAAAAAAMLGRGPGGPGGPGVPPPGVLYGPAGVPPPPYLTGPGPSPTGAGSFPFPPGAAAAALFPPGLGPGMHAGLDRRLLRAPGRASRPKKQFICKFCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKEKPFKCTECGKGFCQSRTLAVHKILHMEESPHKCPVCSRSFNQRSNLKTHLLTHTDHKPYECSSCGKVFRRNCDLRRHALTHAVGEVNSGDYVDVGEEDEARNLSGDEEDSLLEVDSPRQSPVHNLGESGGSGEKSESERMRLKRKAAIDHEESEEEFDDFDEEEELQDLPRVHDLPREEDDDFDPEDEEQAEVALVARFQASKAAATSQSSSSVGTKPERQGVTHCHHEGGETYTMRPHGEKHQEEPGNSGIASLPVPPSFVRYSVPPGAAGPPPAPPGAPPPTHQHPGHPHLLPPNGDPYLPILHVRRDLHHKSLNLSKAGVPPPPHTPPTIITQPESGKPPNQPLHSPHEAMPSFLGSIPMRKRILPAPTLDLMDPHHHPGLGQRTFVDSPSIYALNMSRHPPRQLLGKPPSTETSGATTEKGPPVAAPPIAPPPAPPRRTGFSIEDIMRR
The following text describes a protein:
Function:
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes adhesion and migration of various cells via the alpha-V/beta-3 integrin receptor (ITGAV:ITGB3).
Miscellaneous:
MISCELLANEOUS: It is possible that the segments of clustered carboxyl groups mediate the strong binding to hydroxyapatite.
Subcellular Localization:
Secreted.
Domain:
The Arg-Gly-Asp (RGD) sequence serves as an integrin-binding motif and is required for integrin-mediated cell attachment.
Sequence:
MRSALLLACLLATASAFSVRSWLRRARAGDSEENAVLKSRHRYYLYRYAYPPLHRYKGSDSSEEEGDGSEEEEEGGAPSHAGTQAAGEGLTLGDVGPGGDAASAHQDCKGGQKGTRGDSGDEDSDEEEEEEEEEEEEEEVEEQDVSVNGTSTNTTAETPHGNNTVAAEEEEDDDEEEEEEEEEEEEAEATTAAATTAQDEVTTLGDEQRSEVTTAGEQWEYEVTVGARGDEGPTESSYGDQEEPARGDSYRAYEDEYGYYKGHGYDMYGQDYYYNQ
The following text describes a protein:
Function:
May inhibit cell proliferation.
Subcellular Localization:
Mitochondrion. Golgi apparatus. Cell membrane. Nucleus.
Sequence:
MFFISKLSLSNIHVRLTAKGLLRNLQLLSGCKLAVGFLAVDKNKSRTNSKNPQPPTNGQPDLVPPESKSRNVEYYKAQCEKKNQTIRQLENTLLSNNRRFEAVAVVIKHLYAEHDEVMKQRRDLSQELVTLREELVSSGHSCERLEQEKEDLRSAFDGVLQKVQEQHRLDLADLEERLKTFYSTEWEKVHQAYQEEADKCKAQMEQQLEEIRSKHEALKKELESSHIEEVDGLKQQFEESFKGFKQSHEKEMQNLNETLKESEETLSNQIQDLMTENDSLKEKLNAEVKRRMELAEKTQDSHTLYLEQELESLKVVLDIKNKQIHEQDKKLMQIDKLMERNVKLDECLKKLQQENEDLKARMDRHAALSRQLSTEQAVLQESLQKESKVNKRLSMENEELLWKLHNGDLNSPRKISPSPSLNLQSPRTSGMFSSPPVSPR
The following text describes a protein:
Function:
Two isoenzymes, hexokinase-1 and hexokinase-2, can phosphorylate keto- and aldohexoses in yeast, whereas a third isoenzyme, GLK, is specific for aldohexoses. All glucose phosphorylating enzymes are involved in glucose uptake.
Miscellaneous:
MISCELLANEOUS: Present with 21100 molecules/cell in log phase SD medium.
Sequence:
MSFDDLHKATERAVIQAVDQICDDFEVTPEKLDELTAYFIEQMEKGLAPPKEGHTLASDKGLPMIPAFVTGSPNGTERGVLLAADLGGTNFRICSVNLHGDHTFSMEQMKSKIPDDLLDDENVTSDDLFGFLARRTLAFMKKYHPDELAKGKDAKPMKLGFTFSYPVDQTSLNSGTLIRWTKGFRIADTVGKDVVQLYQEQLSAQGMPMIKVVALTNDTVGTYLSHCYTSDNTDSMTSGEISEPVIGCIFGTGTNGCYMEEINKITKLPQELRDKLIKEGKTHMIINVEWGSFDNELKHLPTTKYDVVIDQKLSTNPGFHLFEKRVSGMFLGEVLRNILVDLHSQGLLLQQYRSKEQLPRHLTTPFQLSSEVLSHIEIDDSTGLRETELSLLQSLRLPTTPTERVQIQKLVRAISRRSAYLAAVPLAAILIKTNALNKRYHGEVEIGCDGSVVEYYPGFRSMLRHALALSPLGAEGERKVHLKIAKDGSGVGAALCALVA
The following text describes a protein:
Function:
Activator of apoptosis, with grim and rpr, that acts on the effector Dredd. Seems to act genetically upstream of baculoviral anti-apoptotic p35. Blocks Diap2 from binding and inactivating the effector caspase Drice. Might regulate apoptosis downstream of Clbn/NEMF.
Sequence:
MAVPFYLPEGGADDVASSSSGASGNSSPHNHPLPSSASSSVSSSGVSSASASSASSSSSASSDGASSAASQSPNTTTSSATQTPMQSPLPTDQVLYALYEWVRMYQSQQSAPQIFQYPPPSPSCNFTGGDVFFPHGHPNPNSNPHPRTPRTSVSFSSGEEYNFFRQQQPQPHPSYPAPSTPQPMPPQSAPPMHCSHSYPQQSAHMMPHHSAPFGMGGTYYAGYTPPPTPNTASAGTSSSSAAFGWHGHPHSPFTSTSTPLSAPVAPKMRLQRSQSDAARRKRLTSTGEDEREYQSDHEATWDEFGDRYDNFTAGRERLQEFNGRIPPRKKKSSNSHSSSSNNPVCHTDSQPGGTSQAESGAIHGHISQQRQVERERQKAKAEKKKPQSFTWPTVVTVFVLAMGCGFFAAR
The following text describes a protein:
Function:
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MTLIDLANPTRFLALTARVLPWLAAATVILLAIGLYQSALAPDDYQQGATVKIMFIHVPNAWLSMFVWGVMSIASLGTLVWRHPLADVAAKAAAPIGAAFTFLALLTGSLWGRPMWGTYWEWDARLTSVLILFLMYLGLMALWRAVDDPSRAARAAAVLTLVGAINLPIIKFSVDWWNTLHQPASVMRMGGSSLDKSFLIPLLVMAIAFTLLFVTLHLAAMRNEILRRRVRSLQMMQASRMAFSSEMGAGSRQNNASNEVGAA
The following text describes a protein:
Function:
Probable transcription regulator that binds specifically to the DNA sequence 5'-CATGC-3' of the IDE1 element found in the promoter of the barley iron deficiency-inducible gene IDS2.
Subcellular Localization:
Nucleus.
Sequence:
MADTRGSTSSGGGDDRGREGHDDFTGGGQYNRYHRILEAVPSPLVRRENGVHHQYPTGLIHHPSSTMPVAPCSYVPRYTMVPTSAMLPLQHHHRQLQISQENFQDRVPSNNVAAPHLPSNFQDLRPMCNGPPFMSYGQTASNRNVLYQNLTPYSFNAWASNNMPRNPVYTSYHPTAIEDPHATPFHINNHDTDQGFFTVSTSFRVDQSFVHAPSPFPPVSSSSRSFSSAQISNGPIDAKKAKKSDIKDQPIVLRRSDTESEKNDELDQTPASEPSSMSHNSANSTIRFNCREYRVILRKELTNSDVGNIGRIVMPKRDAEAHLPALHQREGVMLKMDDFKLETTWNFKYRFWPNNKSRMYVLESTGGFVKQHGLQTGDIFIIYKSSESEKLVVRGEKAIKPNVIMPIVDCSCKNDLNNSEECGFAISLLTKKT
The following text describes a protein:
Function:
Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
Domain:
Contains an N-terminal helix-turn-helix DNA-binding domain, connected via a linker to the central catalytic domain and the C-terminal domain, which plays roles in dimerization, catalytic function and DNA binding. The N-terminal domain is required for both ligase and repressor activities. It may orient the active site and thereby play an important role in enzymatic activity.
Sequence:
MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
Sequence:
MGAHLGRRYIWGDAEVEPDPLKMPTFPPEYGLPERKERVMVATQKEMTDAQLLLKQRDYCAHYLIKLLKCKRDNFPNFLACKHERHDWDYCEHLDAVGLGGENKGSKSRRRRKEWEKRKGGLREGFWR
The following text describes a protein:
Function:
Component of the TREX-2 complex (transcription and export complex 2), a muliprotein complex that functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
Subcellular Localization:
Nucleus.
Sequence:
MNHGGNTQAVAPMDPNSIENRYGVDGSQTQKYSYQYSTGSESAPWTGHSVENQAVENGNYSNSNYYHPQPTGPATGNVQEIPNTVSFTISSTSGTANVAQDYSGYTPYQTSSDPHNYSNTGYSNYYSGYQQQPSQSYPQPVGAYQNTGAPQPLSSFQNPGSYAGTPSYSGTYYNPADYQTAGGYQSTNYNNQTAGSYPSTNYSNQTPASNQGNYTDYTSNPYQNYTPDAANTHSSTIATTPPVHYQQNYQQWTEYYSQTEVPCAPGTEKLSTPTTSAYSQSFPVPGVTSEMPASNSQPAPSYVQPWRPETDSSHPPSQQPGAAVSTSNDTYWMHQAPSLQAHHPVPPQNNYQSPLETKPLYETPFQGHQRATYPQEMNSQSSFHQAPLGYRQPTQTAPLVDSQRVSKVQIPTNPRIASNLPSGFTKMDKDSTAASAAQAPAYVSVSMPKPKDHTTAMSDPGTFPKSLRGFVERAFARCKDDKEKESCEVALRKIVKKAKEDNTLYTRDWDTEPLSTVTTTNVTNSESSSAQLSSLQNKSPTRRPKSRWEPLVEGKPFVKPASTFSSAVKFGVWNHQNENNKKSSESFQKVDAATGFKPTYSGQNSAKKSFQRPVKRQRFSGGAATAIDDEASSDSDKDLTPYYSSAMALAGSAEEKKRRDSRSKRFEKIQGHSRGNDLTKPKNANVGNLHSRRATALRLSKVFDESGSRAVEDIDWDALTVKGTCQEIEKRYLRLTSAPDPATVRPEDVLEKALIMVQDSQKNYLFKCDQLKSIRQDLTVQRIHNHLTAKVYETHARLALEAGDLPEYNQCLSQLKTLYAEGVEGCSLEFAAYSLLYITLHSNNNRELLSSMSRLSEEDKKDEAVRHALSVRAAVTSGNYVMFFRLYKTAPNMNSCLMDLYVEKMRYKAVNFMSRSCRPTIPVSYIVQVLGFTGAASEGTDEKETDGMEDCLEWLKTHGANIITDSNGDMLLDTKATSTSLFMPEPEDAVAHGDRNLDVNDFFTRT
The following text describes a protein:
Function:
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis.
Sequence:
MDGQIDKMEKRYSMTKLENRLRTFQDGVALEKKKLKWSFKVIPYQAMAKLGFYFDPVIDPKTSKLKKDSVRCCYCHRQTYNVRDCRSKRKDVLETLSNIMRQHLTVTDNKQVCLLIYLRNKLLTDYSFHMGVSDWKNDKYFSNPDDENVINLRKFTFQDNWPHSGSQNEHPLGIEKMVNAGLMRYDSSIEGLGDPSMDKTLMNDTCYCIYCKQLLQGWSINDDPMSRHYKVSQNGNCYFFQTRNRFERIKNDNDSITKNCEVSPTLGENGKREVINTKTASQRQCPLFESPPSSTGPQLDDYNEKTDISVIQHNISVLDGAQGENVKRNSVEEKEQINMENGSTTLEEGNINRDVLADKKEVISTPTAKEIKRPNVQLTQSSSPIKKKRKFKRISPRKIFDEEDSEHSLNNNSANGDNKDKDLVIDFTSHIIKNRDVGRKNAILDDSTDEFSFSNQGHNTFDIPIPTSSHLLKGIDSDNDNVIREDDTGINTDTKGASSKHEKFSVNSEEDLNFSEVKLTGRDSSTNILIRTQIVDQNLGDIDRDKVPNGGSPEVPKTHELIRDNSEKREAQNGEFRHQKDSTVRQSPDILHSNKSGDNSSNITAIPKEEQRRGNSKTSSIPADIHPKPRKNLQEPRSLSISGKVVPTERKLDNINIDLNFSASDFSPSSQSEQSSKSSSVISTPVASPKINLTRSLHAVKELSGLKKETDDGKYFTNKQETIKILEDVSVKNETPNNEMLLFETGTPIASQENKSRKLFDEEFSGKELDIPIDSSTVEIKKVIKPEFEPVPSVARNLVSGTSSYPRNSRLEEQRKETSTSLADNSKKGSSFNEGNNEKEPNAAEWFKIDENRHLVKNYFHDLLKYINNNDATLANDKDGDLAFLIKQMPAEELDMTFNNWVNLKVQSIKREFIDDCDKKLDILRRDYYTATNFIETLEDDNQLIDIAKKMGIL
The following text describes a protein:
Function:
Essential developmental role during embryogenesis, in particular the normal development of the nervous system. May be involved in some aspect of cell adhesion.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MEAKMNLHVCALALLLFGSIATVRGRAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNEED
The following text describes a protein:
Function:
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MDSNYVLKGDEFMMKGDKALKGSTFGNIFGSKGERAEKALELYKSAATQYKLGKKWEKACEAYQRCITCDQTLKSGETGDFYIEAAKAISNVNKAESIQLYEKAIEHYANENRLDNASRYKKEIAQIYESEFEFHLAVKAYQEAADLFQADGKRTSEYNQMRLKVAELSTLNATGDLIAAIKIFEEIGDKYMENKLTAPSAKELYFKSCLLYLCNNDSVGCGIALERYLDKDPSFASARQYKFVVNLIKAVDNNNVQMFSDECFDFNKIIPLDKWKLNVLNKIKEGMQPIQQVEDGGFR
The following text describes a protein:
Function:
Component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom20 and tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein.
Sequence:
MSGISNAENGKAIVSSGVLNSVSAFVRRHRTFVYTIGAVAVFATVGGVYHVQQKKASHKRSKKLKAHQDKAESKVNEGKNEAAKVVKEEDLKSSETGKDVETAAAAAAAAKKKKKNKKKVKAKKVGDSSVDKIATEESVKSMTKEERAKLAAELKTLGNKAYGQKEYANAIDYYTQAITCSHDPIFFSNRAACYAAIGDFEQVIKDTSEALSLDSSYVKALNRRSAAYEQLGKLDEALMDSTVSCIFDGFANESMTATVERLLKKVAEKKSSALLKERPPKLPAASFIQTYLDSFHAQPKPLFDNKFDGDAALAEAYEYLEKGEYQLSYDKAKESCLGSFSSPSVNARTHNLVGTFKFVSGDSKGSMENFNAAIKLDRKFIQPYIRLSAAYLDENDNEKMWKVLNDAESVDKTDSDLYYHRAQVRFVSGEFAEAISDYQKSIALDDSFIYSHIQLGVAQYKTHAIAESMKTFEDCKKRFPNSSEVYNYFGEILLDQQKFDDAVKNFDHAIELEKREHLTIMSAMPLINKALAVFQWKKDISQAENLCRQALSADPECDIAIASMAQFLLQQGKAREALEYFEKSAQLARTESEMVNAFSYAEATRTQIALTEKYPQLVGRLSNPM
The following text describes a protein:
Function:
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
Subcellular Localization:
Periplasm.
Sequence:
MKKCSIILASVLLATSINAIADTPTPLNQQQPLEKIAPYPQAEKGMSRQVIFLEPQKDESRFKVELLIGKTLNVDCNRHMLGGNLETRTLSGWGFDYLVMDKISQPASTMMACPEDSKPQVKFVTANLGDAAMQRYNSRLPIVVYVPQGVEVKYRIWEAGEDIRSAQVK
The following text describes a protein:
Function:
Has ATPase and non-specific DNA-binding activities.
Sequence:
MDLQAIPGVGAKTADALGSLDDPEGALERGDVAAVAGAPGVSEGRAARIVRNAIRVRHDDPGGFLATDRAAEIHERVLGLLQERAVTEYARQRLRTFYPSAADSRIAEVNAFVADAMQRTPRDDVLEALAGVEPLSAPSGVSVRERCVATTDAETYSDAAAAFPELSVEIVEDARDLAELARGYTTVVALDEAFVGVEVEGDVRVEPDAMERPAEVVPERVLSFFAANRDRIRAAVSVHEAAGIDTDVDLDALDGALAHLEGDGSVAGDDELDRLTRAVNDLDAAVSDAESVANDRLREAIGEQDVTIEGADLLSLVERGAGVDSLLGRELADEYDDAVGAARDALEEQLGLRGEAAKLARRVFGDEPTFPVARDDDAMARVRESLTAARDRRAAGRKRELAATLADLRAPTEALVHDALEVDVALAVARFAADFDCVLAERGGRGFRIEGGRNPLLDVAFAETEPVEYGVDGVALLSGVNSGGKTSTLDLVAVVVVLAHMGLPVPAEAARVPAIAELHYYAKSQGTLDAGAFEATLRDFASLTERVADDEGGEESAASRLVLVDELESITEPGASAKIIAGILEALHEAGASGVFVSHLAGEIRDQCGFGVTVDGIHAAGLEDGELVVERSPVKDHLARSTPELIVEKLAEADGAVGEGFYERLLEKF
The following text describes a protein:
Function:
5'-3' DNA helicase involved in DNA damage response by acting as an inhibitor of DNA end resection. Recruitment to single-stranded DNA (ssDNA) following DNA damage leads to inhibit the nucleases catalyzing resection, such as EXO1, BLM and DNA2, possibly via the 5'-3' ssDNA translocase activity of HELB. As cells approach S phase, DNA end resection is promoted by the nuclear export of HELB following phosphorylation. Acts independently of TP53BP1. Unwinds duplex DNA with 5'-3' polarity. Has single-strand DNA-dependent ATPase and DNA helicase activities. Prefers ATP and dATP as substrates. During S phase, may facilitate cellular recovery from replication stress.
Subcellular Localization:
Chromosome. Cytoplasm. Nucleus.
Sequence:
MALQSPIAGLKTITGYILPEEQAVQPNKDDGLESEDEEEEGQPEFLDMKEMNSVSSGGNMFKSLVPTSKEVSILVGKKTYKVEGRFPLCDPWWEVTCTIRLGRLKAFVKGYPFYRLRTHLKSEGRSLLSLFLTACKAQADHVKMFMDWLPTDRRVELVNVLDVLQEFEDSSLEHEAVAQQLKSSVNCSVVWTHVKAASLYPGIMKYLPTLLPGQYLDIIKRARIEDIPETSAMDEDPQNEQRKTNVLSKLEELINTNNVWKLGFNYIMFKELHLIRCEAKLEAFKLCDLFSAIPLLQRNALILYAELKKHCRVTGSTYITQEMLVDKIFSETGADGAWAALHFLVTQGVLMKESTKVALRNLLKYEKGIAECLTGLVQGDPWKIHLDVKEVLREAQIKRLRAKACEKHNATMKSKDDANTSASAAENSTAVFEQLGIDLDQPGTSSMVHNGETPSCDDSENTTLTIKEENLTSDSDSDLDIDPSTIELDCDQVRAAEMMCANPVTVISGKGGCGKTTVVSLVFKAAMEQQTSDLEEVQKACEDFQNDSHGSSNGLALDVHEEKNHSEKSISNEKSVEVLLTAPTGRAASLLTKRTGFTAYTMHQVLWSFMTVDKDRSGNPQDWKFSKVRVLVVDEGSLVSVQILHSILSMLTKHAQLQKFIILGDVRQLPSIEPGNTLYDLFEGLRRVRWAIEMRTNHRAESELIVRNAGLISEMGKKKYYKPLDFDATIDMTNPSAVPSDKRFIFIKISSDNFSFDLQEAILFLLKEAPGLKDHILSQFVAFRRKDCELINELCCRHYSNHTTKTAKKTFNFQVGDKVCCTKNGYVTDYDKKETSLADIRASHNRAESQQDDQKKEKKEKKERLCNGEIFFIKDDVTKSVENEKNKMVRQLTLDDKSDRQVTCNYKELQRECKLRHSWARTIHTFQGSEAETIVYILGDSPAQNWQHVYTAVTRGQKRVYVVGTEYDLEGAIRKRITPRNTRLCGFVNTKVGQQDPLTTSASTQRQAETTLNHSFGHSQSTPVASQTPIRPQMLSSTRPSCARNLYTDKNGEGDQTSNISLQDDMAFSQAYSWSPMDSCDEAGRVQNENMTELSNHVDDALLATLSSSPNESSRGSKRTIAEDIYSTPSKLPKQTASEESPMVSSRLNLLSLSSPDIKSSRQLFQDDTHSHRGQP
The following text describes a protein:
Function:
Acts as a transcriptional repressor. Negative regulator of jasmonate responses. Connects the JAZ proteins and the non-JAZ protein TIFY8 with the TOPLESS corepressors.
Miscellaneous:
MISCELLANEOUS: Unlike the JAZ proteins, the stability of AFPH2/NINJA is unaffected by jasmonate.
Subcellular Localization:
Nucleus.
Sequence:
MDDDNGLELSLGLSCGGSTGKAKGNNNNNAGSSSENYRAEGGDRSAKVIDDFKNFLHPTSQRPAEPSSGSQRSDSGQQPPQNFFNDLSKAPTTEAEASTKPLWVEDESRKEAGNKRKFGFPGMNDDKKKEKDSSHVDMHEKKTKASHVSTATDEGSTAENEDVAESEVGGGSSSNHAKEVVRPPTDTNIVDNLTGQRRSNHGGSGTEEFTMRNMSYTVPFTVHPQNVVTSMPYSLPTKESGQHAAATSLLQPNANAGNLPIMFGYSPVQLPMLDKDGSGGIVALSQSPFAGRVPSNSATAKGEGKQPVAEEGSSEDASERPTGDNSNLNTAFSFDFSAIKPGMAADVKFGGSGARPNLPWVSTTGSGPHGRTISGVTYRYNANQIKIVCACHGSHMSPEEFVRHASEEYVSPESSMGMTAASAHT
The following text describes a protein:
Function:
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity).
Subcellular Localization:
Nucleus, nucleolus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
MAPLSTPESISREISVSSDASADESTSLDQMRAPKRRRLSESSTDSYTAAPAPLPSLSRIKKKSSSTNATSSRKDDENPVLIKDALEIGLNAEENSFKALNVAPWLVGSLTTMAVRKPTAIQRACIPEILKGRDCIGGSRTGSGKTIAFSVPILQKWAEDPFGIFAVILTPTRELALQIFEQIKAISAPQSMKPVLITGGTDMRSQAIELAGRPHVVVATPGRLADHINTSGTDTVAGLKRVRMVVLDEADRLLSPGPGSMLPDVETCLSFLPGPSQRQTLLFTATLTPEVRALKSMPQTPGKPPIFVTEISTEAKDTVPPTLRTTYVQVPLTHREAFLHVLLSTESNITKSAIVFTNTTKSADLLERLLRSLGHRVTSLHSLLPQSERNSNLARFRASAARVLVATDVASRGLDIPSVSLVVNFEVPRNPDDYVHRVGRTARAGRTGEAVTLVGQRDVQLVLAIEERIGRKMVEYEEEGVNLEARVAKGSLLKEVGAAKREAMVEIDEGRDVLGRKRNKLKKVR
The following text describes a protein:
Function:
Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.
Sequence:
MRHCGSIYEEMAKQLLATGRWSHLSVRQCSVTKALVISETQKELCDTNMHLLLGEKLPCERVIATRRFMSKRYPSRLGERTNARRSAYDLRSHTSPGLRMPMGSGDDGEVRVVDFVENTRSITLKSSMVTALLKHHNYNWNTLGDYLPMSFKLTPCQSSRDERQQLLATLKGRMRPLHEGDEPCLWIAKSSAGCHGDNIEIFRGDYRGILKLLRFIDSQHGSQPWIAQQYVDRPLLYHKRKFDIRCWALLLRDMYEIYVHEELVMRTSSVPYNRESATSKTPTGRLAHITNHCVQETSKMYSLYEESNELWREHLDGLIRYKGTVRAAKLKQEKYTPLCSPRPQEPNRGDVPYPTRYSNDSRESLYPIREAYRGDSTTAPRFVSVRDEPTTITLDNHVMPQIHFIIRDSLLAARSHVPGEPAIPPTHTFQVFGYDFLIDENLKVWLLEINGAPGGPDRLKPALVKDTIELAVAPYFPGTMNLKAKRHNGYVRVYP
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.
Miscellaneous:
MISCELLANEOUS: Present with 1750 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Sequence:
MSQKDNLLDNPVEFLKEVRESFDIQQDVDAMKRIRHDLDVIKEESEARISKEHSKVSESNKKLNAERINVAKLEGDLEYTNEESNEFGSKDELVKLLKDLDGLERNIVSLRSELDEKMKLYLKDSEIISTPNGSKIKAKVIEPELEEQSAVTPEANENILKLKLYRSLGVILDLENDQVLINRKNDGNIDILPLDNNLSDFYKTKYIWERLGK
The following text describes a protein:
Function:
Binds the lower part of the 30S subunit head.
Sequence:
MSSVKNVIKDNYNMMLLKDYLRDAIKEAGFSHAEISKTPTGTRVALHVTRPGIVIGRKGSGIRDLTDKLATDFGLKNPQISVVEIEKPELSPSVMCNRMASHLERGTAFRRATMWTLKQIMENGAMGVQITISGKLRGDRSAFEKHTAGILPRAGHHAEVIVAEDIAHVGTAMGLIGIRIRIARKEKFVPEFEMKAEKPKKAKQVKDAETGKMRDETAAEKKARTESEQIAIEEEKMKDLETLEEEEAKLK
The following text describes a protein:
Function:
Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex Required during embryogenesis for cilia formation in multiple organs such as the pronephric duct.
Subcellular Localization:
Cell projection, cilium membrane; Lipid-anchor. Note=Associates to the cilium membrane via palmitoylation. Localizes to proximal ciliary membranes, to an inversin-like subciliary membrane compartment, excluding the transition zone.
Sequence:
MFNLMANCCNWLKRWREPARKVTLVMVGLDNAGKTATVRGIQGESPLDVAPTVGFSKVDLKQGKFEVTIFDLGGGKRIRGIWKNYYSESYGVVFVVDSSDVQRIQETRDTMAEVLRHPRIAGKPVLVLANKQDQDGAMAEADIIETLSLEKLVNENKCLCQIEPCSAVLGYGKKVDKSIKNGLNWLLNNIAKDYEAISERVQKDTAEQKAQEEQDKKERAERVRRIREERDRQEREEAEREGRTLKEEELDDVNMFNPFQPINNVLTENQDRLNREKEMQRQRENGQQGSVQEQIALQDEEEEEEDEESERQTPESTESGAVDQTKKKTRKLRLKRKHRVDPLRMEEAAPKSPTPPPLPVGWATPKVSRLPKLEPLGDTRHSDFYGKPLPPVAIRQRPNSDTHDVIS
The following text describes a protein:
Function:
Required for 60S ribosomal subunit synthesis. Probably involved in the processing of 27S rRNA to produce mature 25S rRNA.
Miscellaneous:
MISCELLANEOUS: Present with 4990 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MEETIENVEVPSSNVSKQNDDGLDMKTLFVRSIPQDVTDEQLADFFSNFAPIKHAVVVKDTNKRSRGFGFVSFAVEDDTKEALAKARKTKFNGHILRVDIAKRRDRSKKTSEVVEKSTPESSEKITGQNNEDEDDADGEDSMLKGKPKLIIRNMPWSCRDPVKLKKIFGRYGTVVEATIPRKRDGKLCGFAFVTMKKISNCRIALENTKDLKIDGRKVAVDFAVQKNRWEDYKKAQPEMNDKDDNESGNEDAEENHDDEEDENEEEDRQVDQASKNKESKRKAQNKREDFSVFVRNVPYDATEESLAPHFSKFGSVKYALPVIDKSTGLAKGTAFVAFKDQYTYNECIKNAPAAGSTSLLIGDDVMPEYVYEGRVLSITPTLVREDAGRMAEKNAAKRKEALGKAPGEKDRRNLYLLNEGRVVEGSKMADLLTNTDMEIREKSYKLRVEQLKKNPSLHLSMTRLAIRNLPRAMNDKALKALARKAVVEFATEVKNKERHPLSKEEIIRSTKEKYKFMGPDEIEAQKKKDKKSGVVKQAKVIMEVKGSTAGRSRGYGFVEFRDHKNALMGLRWLNCHAVTSDEILEGLNDDEKKQVDNDLGKGRRLCVEFAIENSNVVKRRREQLKQARTKRTRPDNEDTGDVGESENKKPKKEEATTPTNPDDKKMGDDIKRIIGFKRKRKHAKK
The following text describes a protein:
Function:
Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=Mitochondrial matrix soluble protein partially associated with the inner membrane.
Sequence:
MFRTLKASQKRSLVNLMFGTTALFATATVIFPSLLPCPAMKNPYLDTQSDPGYEELPENSRVIVIDQQSPKSSLVASKQNNPPSKS
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.
Sequence:
MAASTSMVPVAVTAAVAPVLSINSDFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALPLAELQPPPPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGETPTTEVPAPFFLPASLSANNTPTRRVSPLNLSSVTP
The following text describes a protein:
Function:
Component of the menaquinol:cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein.
Sequence:
MSEKEHRVSRRQFLNYTLTGVGGFMAAGILMPMTRFALDPVLRKEAGTDMVAVAQVKDITTEPKRFDFKVKQVDGWYKSEEPKSAWVHKDESGDIVAFSPVCKHLGCTVNWNSDKAHPNQFFCPCHGGRYTKDGINIKGTPPLAPLDVYESKVKDGTLYLGKAKPRGGAK