lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Required for mitochondrial iron-sulfur proteins biosynthesis.
Miscellaneous:
MISCELLANEOUS: Present with 2440 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MPGFTAPTRRQVLSLYKEFIKNANQFNNYNFREYFLSKTRTTFRKNMNQQDPKVLMNLFKEAKNDLGVLKRQSVISQMYTFDRLVVEPLQGRKH
The following text describes a protein:
Function:
Part of the homotypic fusion and vacuole protein sorting (HOPS) tethering complex involved in endo-lysosomal vesicle trafficking and lysosome biogenesis, but unlike in many other species does not form part of the class C core vacuole/endosome tethering (CORVET) complex. The HOPS complex facilitates docking and fusion of lysosomes with late endosomes and several other types of vesicles. The HOPS complex is also involved in autophagy, pigment granule biogenesis and crinophagy (the elimination of unused secretory granules through fusion with lysosomes). The HOPS complex probably instigates autophagosome-lysosome fusion by binding autophagosome-associated Syx17/syntaxin 17 and promoting assembly of the trans-SNARE complex. Independent of Syx17/syntaxin 17, HOPS is involved in biosynthetic transport to lysosomes and lysosome-related organelles such as eye-pigment granules. Required for autophagocytosis-dependent remodeling of myofibrils and transverse-tubules (T-tubules) during metamorphosis.
Subcellular Localization:
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side.
Sequence:
MDISVFEWKKVDLFNIIVVPFVKIPNTAEISCYCFPESKSSTEERNIKLVICDKNRNILIYLSNWECITFKSPSTRKAIALCSLTSNNSLATVTPDINNGIHIDIFDLNRLTKKQAAPIIASAYTQPSSTPLCLNADVIDDKLFALAIGLGNGDILLHYGKITKNFSANIRQHTVSGNAVNGIHFDFKTQPLDTTQIMFVTCVQGVYCFMLKEKCIMDTKFVLDNDKGNLNYRSIMCKAGGGEINDSMLVVGRADAVYCYTPEGRGPCFAIEGAKECLAWVGHYLIVGVKNSNLKQNATTLIVLDTENKIIVFQRQFQELFYVISENNFCYIVTNSGDTDACNMLMLEKNSIDVNIRLLVEKHMYNIALRLLHREGYTSSPETALVRFQYGNHLLQKGDFSRATQEFIKTIGFIKPYAVISKLLYSRYNTYLLNYLTEWKKKNESSSCHTRLIECCIKRDQIEHEMQQDDFKHYKSPAKIKHLATLSKMYFACTPSNQVPVEEEHLLHQLLEYGPASLAVDLTTYLNNITFENVKESKNILSFCSILADHNDYCAKMLAKIIEAFPVCDEKLLFYLLVFYFKLWRLDKVTSSFVSDFIKTHSLRMDKTIIVSRLYTFFNVTQRIHGHQKNTGTLHNETIDKCIENLIKNNPDVALNENLSKRSFLMMLKSSCSTEEIKAIKIKPIFKDRLLRSIVDSANELKLVENFNEKIKRSRSMLSLYTNNPIEFRNDKCDICREMLSMQSIYFLCQHSFHEECLNYKSTKRQEKFLCIICKTRNLLSPKHSSNFSCDSSDTIAVLAKIVSIGNKLETKLMIRGRQKSDGVTCNPFN
The following text describes a protein:
Function:
Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning.
Subcellular Localization:
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Cytoplasm, perinuclear region. Cell membrane; Single-pass type IV membrane protein.
Domain:
The C-terminal transmembrane domain (TMD) is necessary and sufficient for membrane targeting.
Sequence:
MRLPEQPGDGKPENETKGDQETPERGEEPRRSPAPDFPTWEKMPFHHVTAGLLYKGNYLNRSLSAGSDSEQLANISVEELDEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMDGDGQVDFDEFMTILGPKLVSSEGRDGFLGNTIDSIFWQFDMQRVTLEELKHILYHAFRDHLTMKDIENIIINEEESLNETSGNCQTEFEGVHSQKQNRQTCVRKSLICAFAMAFIISVMLIAANQILRSGME
The following text describes a protein:
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MASNLKMKNVMVNYDNDNSDDDEDEKVSGKKKELLDLPLEKLNLGPKKKLLVLSLGGLLVDRVHRRNESAVRRFTPDLAHGNFLVFKRPYCDQFMKFCLERFEVGLWSSAMDRNMDPIFDNIMVGLRKKLVFIWDQDNCIDSGFSTVEKHNKPIFLKQLKKIWENNSYGGRFSEFNTLLIDDEPHVALLNPPNTGVFPPAYKVRNRGDTFLGPKGEMQEFLDGLVDANDVPTYVKGHPFGQPAITDSHSDWDYYVKIIRAAKDPGFGVYKSDSDYSD
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Subcellular Localization:
Mitochondrion.
Sequence:
MVRKFSKFPKKPADWVPPSAPLSMRKQVFLPDFTIALIRTPFLPPRYATFYVPLNFNKLDMRDYLQRLYGVGVLRIRSYVEQQKVTRLRPLGKFGYGRLRRPMSKKKMTVEMKEPFVWPEAPTDMSPWEKDQYFNAEKYQEEIQRSQRPDAAMEPNKAEREEYAKEAKQLLEGTKTWRPTWQALGLNYDRSLLKATKGSASTSS
The following text describes a protein:
Function:
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
Subcellular Localization:
Cytoplasm.
Sequence:
MSIFIGGAWPYANGSLHLGHIASLLPGDILARYYRSKGENVLYVSGSDCNGTPIAIRAKQEGVTAKEIADQYHEEFQRCFRSLGFTYDCYTRTDSEHHHETVQNVFLRLLEEGHIYKKIVEQAYCETCTQFLPDRYVEGICPHCHEAARGDQCDACSAILDPLDLLEKKCKLCGSTPSVQETEHFYFALHTFQEQIKRAVEIAKQTGTWRDNAIQLTERYVKEGLLDRAVSRDLPIGVPIPVEGYEDKKIYVWIEAVTGYYSASKHWAEETGKDDQEFWDSEAKTYYVHGKDNIPFHSVIWPAVLLGIGEEAIPRHIVSNEYLTVEKRKLSTSKNWAVWVPDILERYDPDSIRYFLTVNAPENRDTDFSWREFIYSHNSELLGAYGNFVNRTLKFIEKYYGGIVPKRSIEVELKDKVEGLYKHVGEAIEQTKFKVALETIFDAVRFANKYFDEKQPWKQREDDPVSCEETIYNCVYLIANFANLLEPFLPFSSERVRNTLSIVKRNWEPQNTLPSRIDSVQPLFERIDVKQIEHEIEKLYGAVK
The following text describes a protein:
Function:
Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MEEAAGDEEWYTIALWGYFAMAAIMFVLVNFCLSAPYGRHVRRGWGFSVPVREGWIIMESPALFVMALVYHAGQFHLQHVPHVLLRMHQMHYFHRTLVFPFRMRADGKAMPAAVVASGFFFNVYNSYIQARWISHIGVYPSSWLTSPQFLLGVAIFLVGFLGNIWADNVLLNLRDHKEDRSYKIPRGFLYEFITCPNYFCEIIEWLGWAIATNSVAGFFFFLSTLANLGPRAKTHHEWYHKKFNDYPRNRKALIPFLY
The following text describes a protein:
Function:
Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
Subcellular Localization:
Cell membrane; Single-pass membrane protein.
Sequence:
MAKKESFFKGVKSEMEKTSWPTKEELFKYTVIVVSTVIFFLVFFYALDLGITALKNLLFG
The following text describes a protein:
Function:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.
Subcellular Localization:
Chromosome. Cytoplasm.
Sequence:
MQGLRVRGDADGAAQPSPSSSLGTGSRVLQESDETLEAAEVRVAQDDAHSGAGLAPSRKSNPPSQDGVPVLQSRSVERQAREELAPELLNQMLANCLKLASENKITQKNTWELKLIDHASDLVLADHDDGSQTNFQKASCVLETGMKIYATRVDATHSETYKVLGGLNRTTAEQADTDAEGGDADGGEDEERQGEARKERKGHSATLEPTLEALNLKKFDTAFAVDPLFHQTSAQFDEGGAKGLLLNNLSVFRGCEIVFDSGDIPDRGSAKPGPNPGSDKWANLTFLQDRIQAMCRGVQRALHISPTLQEIVKLLNDPYRAAAEAKTADESSVGGPSGEAFSTPGKGEAAQPPLDFGWGGGADFAANMDDDFGSMGGGTIGGVLMTMMRGSDVEEDVVRWLEGGAEGRGKSWAGADHWRARGRPKDTEDHGAADAPPKPKRPRNAPFLLDFENLPDLSDPQYAPADDEREICLAPSALTTDAKTLLPEDLHYQPMWLARLFLRPNVVCIPRKVRVPAGTRGGSEAGPAFATQMDFGDAGDFWGDDDDDNGAGGSPFVGGADWNAPDGPEDEADGLVEQPRQVEKVDVNYARTSKQVDVKILKETLWTGLQCAPGQEEEDASEGSRKDGVSFRGLLEHIPADCAAAELPDISVHLCFICVLHLANEHGLAIAGTETMDELVIDKVPFA
The following text describes a protein:
Function:
May be involved in the regulation of spermatogenesis and sperm maturation.
Subcellular Localization:
Cytoplasm.
Sequence:
MAKGKGPKGKKITLKVAKNCIKVTFDGRKRLDLSKMGITTFPKCILKLNDVDELDMSRNMIKKIPDSINKFQNLRWLDLHSNFIEKLPDTIGELASLHYLNLCNNKLTTNTLPVELKELKNLRVLNLGLNHIDNIPTTLGQLKELHEMGAFDNLLTTIPTSIAKLPKLKKLNVKRNPFPQEDDSAEFIDSIKRLESLYLVEAKDLCGPCLKKCQDARDKLNKIKSMAPAQARKPNFINLINPNSTAKESQEEWRMSQSLLELPS
The following text describes a protein:
Function:
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type IV membrane protein.
Sequence:
MAAALSYEDLRKHARYLENEIDLKLVAFSKLGAGIKSPPAHSSSDAVPLLSGEDTFEAMSLEIEELLNKLTQVNDRMGEQPVSGAAMLHTLQRHRDILADLSRDFRKTTSQHEIRREREDLLRGSSDTFRGDGVNNRRDMYLKENQHLHSSERLVNEQISIAMETREHLTNQRQTFKRLQTRFNDLSNRYPVINSLIQRINIKKRRDSIILGLVVSGCTVLMLLYAFH
The following text describes a protein:
Function:
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
Subcellular Localization:
Cytoplasm.
Sequence:
MYRVLLSGAAGSGKGTIARMLVREFEPLGFNYFAAGDFIRDHIARGTEFGVRAQSFLNKGEHVPDSILNGAILAEMLKAGPRVVLDGYPRNMSQLKMVEEQAPLNLIVELKVPRKVLIDRLSKQLVHPASGRAYNLEVNPPKEEGKDDITGEPLFKRSTDQLEVARRRLEVYDKTENKVLDYYKKQNKCITMSGESSKAVFESVAEVMRRDLLTTTPRTAYA
The following text describes a protein:
Function:
Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus. Endoplasmic reticulum.
Sequence:
MTVKAAEASGPALTYSKMRGMVAILIAFMKQRRMGLNDFIQKIATNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKEDFTEIKNHIFFSPINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTDEPVPNSIGQSPDSILITASVKEAAEAFLGFSYAPPVDSFL
The following text describes a protein:
Function:
Key regulator of adhesion dynamics, it acts as an anti-adhesive. Plays a critical role in the regulation of cell-cell adhesion, multi-cellular development and, in particular, the formation of the organising center known as the tip. Required for turnover of paxillin-adhesion sites during cell migration. Plays a major role in normal cell shape, cell-substrate adhesion and actin cytoskeleton organization.
Sequence:
MAVLSLVELCFISIMERMEYNNQALQKIPPQLIERLINFMVYKLPPNHLSLQTISKPIRIKLVRQNRVITMRFSIYNTIDKIIHQIYERIINEEKMEQNEKQKNSSNNNLLSLLTLNNNNQNNNSSIITTTTTTTNNNNNSNCGSSSSSSSSKQILWGSIENYGLFQQSGSFRNARWLQLDKTLAYYEIDSNETLEFKTCKSVLKIRFFGPWERVVHPLHQSTMLDETIKTFVFDESKTVSEISMELAKKLQLKYPEELSLKVQCEEEDDGRGIWLSADLTLPEQGIDPLYTIFLLKRQFFFCKDIIIDFSMDAEMLHFVFCQCLDAIIDTSHPCSPTESILFAALQCQICFGDYVHGSKEIDQIRQRDFLPMEFINQKNILKEILIQYQRLIGMSEQKAKLNYIQLAKSLKTYGYTFFKVTNRQTSIVNNNLSSSGGSGNGSGSGNGSSSSSSNSSSGNNNNHNHHNHQQLFGISSEAVLTLDPMTNNTISLYSLSNIRKWHVLNNVFTIEYNDRKDTFISMEAEAISHVLSSYIHHNLRETPSIQKQWDQNYLSVSGRNSLTNGRKRLSTCSNCSSDSMEFDSSKSNTKDKDWKYQYGLVIKKCALYIEPKKLYINPLSTQITGSMVNKELNKDTKVTKVLKVLTDLSSKMILSFSKSSPAKEREIVVKFSDKKVKSFVVDEQKTVSEITQEIGLKLGIKNPEEFSLQLIVNNKNNNNNNNSNNSSTSSSSSSSVNNSGIFDGLNNSNVNNVFYNSYIVNSSISNNSNSNSNSNILNNSNDEQSTSTSTSSSLGGIWLKPYQPLSEQSISPDSKLLFKKKFYTSDIGAADDCNSDPVYFNLLFFQSKDAIISNTYTCSKEEAIQLAATLFQINFGDHNPNIHKPGFLKSQDLKFFLPPNSLELWGLSFQKIEKSIYKEHQNLRGIKEVYAKYRYVQLCRSLKTFGAIFFSVRQLLPNKTNGSSSSSSNNNGGNSNNGINGNGIITGGNGGSGGGGSGIGGNGSGINTGGNGFGGSQQIPINQPLVLGFSRKCILFMTAKTKKFLVEYPLTHLRRWAYHKDTQCLTLDFGDYEMGRIVLQTTESEEISSYLSDYIDYIQTKLVGSQSFSRSIFNSDNNSSSFFSNSFCNNTTTTTTTTTTTTTTTTTTTTNNV
The following text describes a protein:
Function:
Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr).
Sequence:
MHLVDTHVHINFDVFAADLDQLQHRWRQAGVVQLVHSCVKPQEFDQIQSLADRFPELFFAVGLHPLDAEDWQDNTAGQILAYAKADDRVVAIGEMGLDFFKADNRDHQIEVFRAQLAIARELNKPVIIHCRDAAQTMRQVLTDFQAESGPVAGVMHCWGGTPEETQWFLDLGFYISFSGTVTFKKAEGIQASAQMVPPDRLLVETDCPFLAPVPQRGKRNEPAFVRHVAEAIAALRHVPLETLAQQTTTNARNLFKLPVPA
The following text describes a protein:
Function:
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of sterigmatocystin (ST), a polyketide-derived furanocoumarin which is part of the most toxic and carcinogenic compounds among the known mycotoxins. The first step in the biosynthesis of sterigmatocystin is the production of hexanoate by the fatty acid synthase (FAS) units stcJ and stcK. The polyketide backbone is assembled by the non-reducing polyketide synthase stcA by condensation of the starter hexanoyl-CoA and 7 malonyl-CoA extender units followed by cyclization and release of norsolorinic acid (By similarity). Norsolorinic acid is the first stable intermediate in the biosynthesis of sterigmatocystin and is converted into averantin (AVN) by the ketoreductase stcE which reduces the hexanoate ketone to an alcohol (Probable). Averantin is then oxidized into 5'-hydroxyaverantin (HAVN) by the cytochrome P450 monooxygenase stcF. 5'-hydroxyaverantin is further converted to 5'-oxyaverantin (OAVN) by the 5'-hydroxyaverantin dehydrogenase stcG. The next step is the conversion of OAVN into averufin (AVF) which is catalyzed by a yet to be identified enzyme. The cytochrome P450 monooxygenase stcB and the flavin-binding monooxygenase stcW are both required for the conversion of averufin to 1-hydroxyversicolorone. The esterase stcI probably catalyzes the formation of versiconal hemiacetal acetate from 1-hydroxyversicolorone. The oxydoreductase stcN then probably catalyzes the biosynthetic step from versiconal to versicolorin B (VERB). The next step is performed by the versicolorin B desaturase stcL to produce versicolorin A (VERA). The ketoreductase stcU and the cytochrome P450 monooxygenase stcS are involved in the conversion of versicolorin A to demethylsterigmatocystin. The Baeyer-Villiger oxidas stcQ and the reductase stcR might be involved in the biosynthetic step from versicolorin A to demethylsterigmatocystin. The final step in the biosynthesis of sterigmatocystin is the methylation of demethylsterigmatocystin catalyzed by the methyltransferase stcP.
Sequence:
MPSYAVLGATGNTGRAIVQVLLDRADTDTRIHICAYCRSKEKLFRVCPAAETSKSLSVFQGRLDDDSLIDECLRGTDAVFLVVAIVDNMPGCTVAMQTAEAVVASLQRLRATDPAIRLPRLVILSSASLEPTFCNDVPAPVHWVLKTAVSHLYRDLAAAEAYLRAQSDWLSATFVKPGGLVHDQARGHKVCLDRAQTPLSFLDLAAGMVEVADADDGRYHMRSVSVVPASRVAIFPWDGVYYTFTGLLFHFCPWTYRFLGEYKLQSRKERDKQA
The following text describes a protein:
Function:
Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Displays broad substrate specificity since it is able to catalyze the oxidation of a number of alternative aldose sugars, such as D-galactose, D-xylose and L-arabinose, to the corresponding glyconate. Can utilize both NAD(+) and NADP(+) as electron acceptor. Physiologically, seems to be involved in the degradation of both glucose and galactose through a non-phosphorylative variant of the Entner-Doudoroff pathway.
Sequence:
MKAIIVKPPNAGVQVKDVDEKKLDSYGKIKIRTIYNGICGTDREIVNGKLTLSTLPKGKDFLVLGHEAIGVVEESYHGFSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIHKMDGFMREWWYDDPKYLVKIPKSIEDIGILAQPLADIEKSIEEILEVQKRVPVWTCDDGTLNCRKVLVVGTGPIGVLFTLLFRTYGLEVWMANRREPTEVEQTVIEETKTNYYNSSNGYDKLKDSVGKFDVIIDATGADVNILGNVIPLLGRNGVLGLFGFSTSGSVPLDYKTLQEIVHTNKTIIGLVNGQKPHFQQAVVHLASWKTLYPKAAKMLITKTVSINDEKELLKVLREKEHGEIKIRILWE
The following text describes a protein:
Function:
Acts as a central component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules. CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA. It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromers and in several promoters. The association of CBF3C with CBF3D and SGT1 is required for CBF3C activation and CBF3 assembly.
Subcellular Localization:
Nucleus. Chromosome, centromere.
Sequence:
MPSFNPVRFLELPIDIRKEVYFHLDGNFCGAHPYPIDILYKSNDVELPGKPSYKRSKRSKKLLRYMYPVFATYLNIFEYSPQLIEKWLEYAFWLRYDCLVLDCFKVNHLYDGTLIDALEWTYLDNELRLAYFNKASMLEVWYTFKEYKKWVIDSVAFDELDLLNVSNIQFNIDNLTPQLVDKCLSILEQKDLFATIGEVQFGQDEEVGEEKDVDVSGANSDENSSPSSTIKNKKRSASKRSHSDNGNVGATHNQLTSISVIRTIRSMESMKSLRKITVRGEKLYELLINFHGFRDNPGKTISYIVKRRINEIRLSRMNQISRTGLADFTRWDNLQKLVLSRVAYIDLNSIVFPKNFKSLTMKRVSKIKWWNIEENILKELKVDKRTFKSLYIKEDDSKFTKFFNLRHTRIKELDKSEINQITYLRCQAIVWLSFRTLNHIKLQNVSEVFNNIIVPRALFDSKRVEIYRCEKISQVLVI
The following text describes a protein:
Function:
Involved in pre-mRNA splicing as a component of the spliceosome. May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex.
Subcellular Localization:
Nucleus.
Sequence:
MADYWKSQPKKFCDYCKCWIADNRPSIEFHERGKNHKENVAKRISEIKQKSLEKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEISEPSVSPVTSTVPPTSASNQQKEKKKKKKDPSKGRWVEGITSEGHHYYYDLITGASQWEKPEGFQGNLKKATGKTVWIEGLSEDGYTYYYNTETGESRWEKPDDFIPHSGDLPSSKVNEKSLGTLEESKSSDSHGESDGEQEAGKEKKKEEIPTETQKLIIKFKEKNKNSNKRTEPETQKEKNTQGKNSSGPSEEKPKEKNTQGKSSSGSNEEKPKAHKKPNPYGEWQEIKPEVESHEEVDLELPSAENEYVSTSEADAAGEPQLVFKEKTVTSLGVVADGVAPVFKKRRIENGKSRNLRQRGDDQ
The following text describes a protein:
Function:
Voltage-gated chloride channel.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MNASPHSKPSAALAPSPTAAFFPSTSRVYTSKAATVVDDDEALDEIRRYESFSTVDWVVDNTRERNRLARERQAASAHFVSSSSNAHLGNADAAWGHIGFGRGGVPPRWWSRGPWGRRAWLVWGIVKSASSAFTDSGVIVLVGILIGLNMGVISLATEWASDLKQGYCSSGWWLNQKFCCWEMMDQAGPGGAPLPAAAKALATATVTVTASIGAAAAATDSAPILPATPAATPTAAIRAVAQEAYNLTIRAIPDHQLWSRSAQDVIQDGFGTGLRLLSRAEGAASGAGDLSETCTDWVRWSKWSFPAWIIYMLFAGLLSFICAHLVKSFAPYAAGSGISEIKCILAGFVINGYLGFWTLAIKSLTLPLAIASGLSVGKEGPAVHVACCIGNVVASFFRSFNRSQAKMRELLTASSAAGVAVAFGSPIGGVLFSLEEMAYNFPASTMWRSFLCALAATVTLSFMNPFRTGKLVLFQVSYDRDWHYFEIMFYILIGIFGGLYGAFVIKYNLQVQSFRRSYLVKHGVSEVVVLATLTAFVGYANKFLRIDMTESLEILFRECEGGGDYDNLCQSWAQWRMVNSLLLATVLRTALVIVSYGCKVPAGIFVPSMAIGATFGRMVGILVKALYNAFPHWSLFSACQPDVPCITPGTYAFLGAAAALAGVTRITVAVVVIMFELTGALTYILPTMIVVGITKGVADWFSRGGIAEQMIKFSGYPFLDKDDHNFGIPVADVMRVCPQVLFASGMKLSELEGKLADGSYKGFPLVLAKHDATLLGYVGKVELRYAIGKARRARALDGDTLCLFSVGPNALDRADGVESSAHGAQQQQPDLLSVASLPTTAAADRAVREDMLSRFSGATGAGSASGLGSTSATGVASQRRHESESLIGQLDVEDDRSSAPSYRSRVDAGDNMSSSSDDDAVVGNAGGGVDGESDLDKLELGGWIDPTPLIVQPGMPLETVMDMFKNLGPRVILVVEYGRLSGLVTVKDVLKRIAMQEKAEAAARTAAAAGLPMSGSANSFTGEGAGAGGGELEALLKEAYEWAQEKWALISPRIERISARRASASRGGAPGSQAGQARYSHLRESTEDRYDDSDAVAEDMPMHSTRQTSATKNTRSEHHQFVLGAQDDDDE
The following text describes a protein:
Function:
Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
Subcellular Localization:
Secreted.
Sequence:
MIKTKEVTFVTILIVLCVFISTIHAKRYIEYPIRLDLGKGCDPRFPTAACYKRTPANPYRRPCTTANRCRRSTSSTRVPSLKTFVEIPPM
The following text describes a protein:
Function:
Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Regulates trichome development, production of mucilage and tannin in seed coats, and maybe root hair development.
Subcellular Localization:
Nucleus.
Sequence:
MEVNDGERVVIAKPVASRPSSSSGFRTFTELLTDSVTVSPQTTCHEIVDAAIRPKTLRFNQPVAASVSCPRAEVKGIGNGMSCDDDSDSRNYVVYKPKAKLVSKATVSALANMLQGNRQQTWRQSEAVSYGKSVSQGTHRAGPNLVQKVPSFTESETSTGDRSSVDGYNWRKYGQKQVKGSECPRSYYKCTHPKCPVKKKVERSVEGQVSEIVYQGEHNHSKPSCPLPRRASSSISSGFQKPPKSIASEGSMGQDPNNNLYSPLWNNQSNDSTQNRTEKMSEGCVITPFEFAVPRSTNSNPGTSDSGCKSSQCDEGELDDPSRSKRRKNEKQSSEAGVSQGSVESDSLEDGFRWRKYGQKVVGGNAYPRSYYRCTSANCRARKHVERASDDPRAFITTYEGKHNHHLLLSPPSSSTLPFNSPQLSKQTI
The following text describes a protein:
Function:
Binds to the 23S rRNA.
Sequence:
MEVILLERVNKLGQMGEVVKVRDGYARNFLLKRGKALRATADNRAKYDGMKADLEARNLASKAEASKVAEKIQGKNIIVIRQASEAGQLFGSVNVRDIVVAFEADGISLARPQIQLDAPIKTIGKHTITVAVHPEVEVEITVTVARSQDEAERINRGEDISTRNEDRDAAAEAIAAAGEFFDPEAQHDDVEPAPAAEETEK
The following text describes a protein:
Function:
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
Subcellular Localization:
Cell membrane. Cytoplasm. Endomembrane system; Peripheral membrane protein.
Sequence:
MSHHSDDQLLQAGSDSFWELNNYKRTTKRIEDGYKLCTELQTLIQERAEIEKAYAKNLKAWSKKWGELIEKGPEYGTTEAAWKGMLTEAERLSDLHLKIKANLCTDVTLQIKEWQKDNYHKSMMQIKERKEMEDQFKRAQKPWAKLLASAEKAKADYHAACKMEKSATNQERNASSDSSMSNDQLKKMQERVQKLKDDVAKSRDRYEQTLSEIKEYNPVYIESMTNVFRKCQEMEETRLCFFKNVLFSIHKCLNISEDPSLPQIYKEFHHTINNADHQKDLKWWSNNHGVNMGMSWPTFVEYTEEFRDIAKGIKSKEALPAAPITLIHQRPVAEDVHEYPPPPPANNNRLLGGGNRNSTALSISNSTSNNRTTTPTPNNDSPKSETASTKNEVATTPTRNSPARAAPGGAVVTNGNSGTNGKANDSNPFEEEEEWDEGDGHDNLLVDNGEPGVPVKALYDYEGAESDELTFKQGDLFEKLEDEDEQGWCKGRKDGRVGLYPANYVEVVAT
The following text describes a protein:
Function:
May be involved in the early steps of the plant defense signaling pathway.
Subcellular Localization:
Membrane; Single-pass membrane protein.
Domain:
The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.
Sequence:
MNSNDQDPIPFRPEDNNFSGSKTYAMSGKIMLSAIVILFFVVILMVFLHLYARWYLLRARRRHLRRRSRNRRATMVFFTADPSTAATSVVASRGLDPNVIKSLPVFTFSDETHKDPIECAVCLSEFEESETGRVLPNCQHTFHVDCIDMWFHSHSTCPLCRSLVESLAGIESTAAAREREVVIAVDSDPVLVIEPSSSSGLTDEPHGSGSSQMLREDSGRKPAAIEVPRRTFSEFEDELTRRDSPASQSFRSPMSRMLSFTRMLSRDRRSASSPIAGAPPLSPTLSCRIQMTESDIERGGEESR
The following text describes a protein:
Function:
Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites.
Subcellular Localization:
Secreted.
Sequence:
MASGYDFGWIPVLLSLFTLTDASSQTVNQELSNIFNELWKLDVNRMEPLTNYNISLQGKAGYIPQGSTNVVDHASSPLFVNVDEAKLSSITTYARFMKLLDNYERSTGVAERVTAEEVTENNSFLDAILETAVMKRAHQYLIGKGKSRSDLRQFKSQLYYMWFRLYHRERNGGEDSSGFEHVFVGETKFGREIMGLHNWVQFYLQEKQNLLDYKGYKARANDVPDADDHVLNVQFSWHGLVKPVASAFVGVSPEFEMAVFTILFLTSTEKTTTAVVNLDEYQLEMVVHRHGRCIGTAYPKLLSSNNRHM
The following text describes a protein:
Function:
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Has an essential role in mediating growth by negatively regulating insulin signaling. It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MHHGGAGLGRLTQEEGSSFGLTERDVSLMDNIRRLQSDFELEEESEDENETSCFRTQLGRVNVPESQEGGGSIFETLSEDPTGTASVEIDVAGAEVIKTGEQLCEEVSCSQDLPAREGGQATWSVENMRPEHNARDSIFPSHGTGDFQLRGLEASIDAPEVGETLQQEQGPGDQDGDSDSERYDSLYQEHVRRQRDAAPESRVMEEDLEEDDRFEISQPESDSQQQPLMTNLSQRDQQFLASIRQLDQVELEEEEMSDASETDSDEERPETPRLAANRREDITFDTTLPAMHTYLGEFDDVAGGRAFEEGGSLVTLPLFYLDGVVLFPGDSLPLRVIQPRFQSAVRRAMRQTAHACTIAVVLCRGYLHPEGPGVATVGTTAEIRQVKEQDDGTFNIVAKGRQRFYVRRISFEGDDSASAHVQIIPEERPLRMPRAAFGQLAAWPSPQSGRVPSALESRESAGSPTNLSPTTYTRTPRRASTGGIPTSSISRRGRHPPDVSPSSGPRRSRRRVSFDGGAVGGVLGRLRERPGLAVFDFPIEEERETQGATRKADEPAERPPGISGIGAGATPPAGRQGARHVATPRSALFLPAYKRRKQRRLGKDWEVAASAERAPEEEKQGGGREASHGPEIVWPELCPVRHDLVRGITQEEEAGSQAAGDLAETSIGAETVRGVRVGGEATPQNVDIQRLLESRWAGTNCRWGGFQGERHGSRHDQTPPKASPRQSGDTGDGDESTEKWQGVSKAWAADDATWRIRAPLSAWPYWVYRMHDAYVLARRVADLMRQVVPARKVDDLLNEPEALSYYVASNLPLQDATRQELLETVGTVYRLRKETKILETLDKLRCKACEVVIASKSDLMVMSADGPIGAYVNPHGHIHETLTLRRVQGLALDGFQETENSWFPGYAWTIAHCQNCGYHMGWKFTAVRPGMTPDCFWGVTRAHLAESTASEHQSDPIQMFTW
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MAPSPMAQAGCSGRRRFAVACSVLSLCVRAETAAAAAAAHSRSVAQAQAGAASPMLLMPGADVVSDETVPTPAPAQLTIVYGGRVQAFSDVSADRAAEVMRVAARQDMPPAGGLADLQVARKASLKRVMGKRRDRLGARAPYAPARPPPPKEQQEKDADIWLGLGISG