lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Involved in the control of the SAPK-dependent transcriptional response to peroxide stress. Regulates sty1 activity.
Subcellular Localization:
Cytoplasm.
Sequence:
MSLYKSLDVAIDYAISQLGEFQFQPIRTQSNPSSLLSACLVRAVHVETRRKVIFKFSQQTFKLENEYFLLRQLSSHPNGRNYAIAPAYILLLNETLGALIYDDPGPNILDEWLGNPNPLDLKLFLKFALGVSYVLCFLHEKKIVHGEIRLDTFHYDLNAPIHAKLLTIGSSVSPIRFTLSSLNWKRLYQVQNICHKLQFFSPEQIGNVGRPLDSRSDIYSLGILFYVILTKQYPWGGQSMRIVQSIHMRQFPSVLPRRPDAFPALDQLIQKMTAKSMNSRISSATDLCYTIVELMQEFSTITSSPLLDQKLLSINKPQQEKLKFPKLLLTNSSDYVRIFHELVAFSSKRDLLTSAKRVDKLPKQHLFKYRPVDNEATYCQVVTVTGEKGSGKSNLLNAVADEARKFGYFAMSSFKGHHFSPYSAIFKCVSLIMQQTLREEKQLVTDYFTSLWEFLGFQLIYMGELFEYVPELNSLLSPKYNLHCKRENYFKLKKRDPQQFRSASGRLGFMVCLLEILSFTSRVRPVIIILDELHLADHPSLSLIIGMISHRLPILLILAWDEPVMFKDFSKCLHEAPYAMVTDIRMNLFDRKNITEFLDSTLESPTQALGPLVLLMQKLSKGNPLVLKSLLLIAFANNGFAFHPKSSSWTYDLPVINRSFEALSSYDIPPLLASLLDALLPARCIEFLLWAALLVEPFPFELLRLITTSMHLFIPKEEILDFPLNVLQFDNDNESCQFSETFFREGILSKISLRRAESMHAQIAKELITGTAKEFYDIRTVHHILKGLGVIKKFDNTKPYILALKESADALMQFGSYEYATELLKSCLFLLPRNFWNSKLYTRKDLISIHISLAMCYWWSKDHENAIKVLKNPKLSSSNVYDYLPAFRLLTKIEYYKYQSLRSIDKAQELLSNLGLKLKEPTDDVLREFYDRLSTKFLECDFLVKQSEPLDRKRIDAISVILSECGFVLFNFSQPYYYYFSFLLAEMYLRYGNPSLRYSVMFLASYCFVTRRKPEFLLRISQVDSDLFVIKDRSAVAHAELIYWGLKRELCSTETGSAVTLESILLQCVMFGDKIYGAYCLACLMAQRVFRGDHIHQLLLDQENSETLLLLWDCEPPFTYYLMLIRNSLLALFGLTNNDDPNNILTTKQRTQKDLHDKLTSKKVPCTFCCWYYAGIIFLNTLFHHYEYVMSIAQEVRKLVDGKLYERYYLITRSFIGVAALQLLFYKKNISEFEREKVEDVAHWAQSSLSEMAKCFHAELYKLWVCLLEGLRQRNLGNYMEALRLFEKVTSMGASVFSPIEFPFVLELIGEFYYGRGHKFLAKSYITRALSCLKNIGCYGVENKLRSRYSDLISDVESRGTTVVSIATTTGDYAEKLKLLRNQDINDFSLGLASYSDIFDKPLVTLPVKKSSAVDESENDFYDRNDEESFDIVSLVSVIKCGQLLSSKLRLGPLLTTVIKLVIEYSQAKHAAIILKDASNYTLAAHGNVEKAESFEPPVILSQSDVKIPDSLLSEVFDHCRIVSLYTVSASQDAELLRWLQEEHDMDFFAIIPLQFKESVIGALYLCLSRRAIRTGNVTFLKLLSQQIAISVSNALLFQSLRRTITDNVTLIELQRLSYQRYKAIEEKCITLLDSLPCIVWTLDSDIGEIEYTNASKRNYFGVPEDCHDSLSWKTFIHPDHHHQFQEKLLNLKTLELGDIELLLRMEDGNYHWHLCRGLSFKEDANAKKWIVVCIDINDEKEAREAAMHAVNLKTNFLANMSHELRTPFSSFYGMLSLLSDTKLNEEQYDIVSTAKQSCTSLVQIIDDLLNFSELKSGKMKLEPDKVFDVEENIADCIELVYPSLSSKPVQISYDIYPNVPALLAGDSAKLRQVITNLLGNSVKFTTEGHILLRCMAIDEEINAEENQCKLRFEIEDTGIGLKEEQLKLLFNPFTQVDGSTTRIYGGSGLGLSICLQICKIMDGDIGVQSVYGEGSTFWFHVQLRNVTSKLSQKHFEESHERFANIRQSLKNAKILVVKSFTTSRSIFRSLFSLAVVDTTTIYSDIEQQLIDSLDKRQPYDFLCIEAASGQTEQIITQILSNQKLNKVLLIVLLPSIQRTKVRSDGDPFITSLNKNQSRIFCFREPIRISKLLQNFPALLSKWSTPTKLVEPSQFRASPRKVDQAVVLSSEEKEILQKKYALIAEDNLIARKLLTKQLSNLGFQVHAAVDGVELVKMYEAKQFGFYSVIFADYHMPIRDGAEAVMDIRAYERENNCSTPIPVIALTADIQKSAKQRCLEVGMNFYLTKPFTQKQLVNAVREFVLLEKSAR
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MTMFKEAVTFKDVAVVFTEEELGLLDVSQRKLYRDVMLENFRNLLSVGHQLSHRDTFHFQREEKFWIMETATQREGNSGGKIQTELESVPETGPHEEWSCQQIWEQTASELTRPQDSISSSQFSTQGDVPSQVDAGLSIIHIGETPSEHGKCKKFFSDVSILDLHQQLHSGKISHTCNEYRKRFCYSSALCLHQKVHMGEKRYKCDVCSKAFSQNSQLQTHQRIHTGEKPFKCEQCGKSFSRRSGMYVHCKLHTGEKPHICEECGKAFIHNSQLREHQRIHTGEKPFKCYICGKSFHSRSNLNRHSMVHMQEKSFRCDTCSNSFGQRSALNSHCMDHTKEKLYKCEECGRSFTCRQDLCKHQMDHTGDKPYNCNVCGKGFRWSSCLSRHQRVHNGETTFKCDGCGKRFYMNSQGHSHQRAYREEELYKCQKCGKGYISKFNLDLHQRVHTGERPYNCKECGKSFRWASGILRHKRLHTGEKPFKCEECGKRFTENSKLRFHQRIHTGEKPYKCEECGKGFRWASTHLTHQRLHSREKLFQCEDCGKSSEHSSCLQDQQSDHSGEKTSKCEDCGKRYERRLNLDMILSLFLNDI
The following text describes a protein:
Function:
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
Subcellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein.
Sequence:
MVSIRRTLSPLKRSSPLSNQDDSHISLSRFSSSSSSSSTSPISVLTSLWALLFGVRTSHNPRRQHLPSASSLLIWKKKVIVRSFLFFVIGFLLGLYDLYHHQISYNGTKRENEKRKTVDLTILHNGASASIIRVTQGAETGIDASNSLVSRGVETRIDPGEFGSTRRYDGEKAEVLLIVVTSTSTRAMQGFYLAKLGQTLRLVRPPLLWIVVEEEDDVASLETADALRRTGVMYRHLTCSVSNSTVRNREIRHKNVALEHIERHRIDGIVYFADENNVYSFGMFQRIRDIRRFGTWPVAMFANAKSKVILEGPVCNGSQITGFHVDQSSRRLQRFYVDMPGFAFNSTILWDHEIWKLLTSNVIRQVHNILEEFQVTTFIEQIVEDESQMEAIPSGCSEIMVWHLHLDDSGFTTLEDGNSPETLKLYFLLVYRSSLSLHLFI
The following text describes a protein:
Function:
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein.
Sequence:
MNWHMIISGLIVVVLKVVGMTLFLLYFPQIFNKSNDGFTTTRSYETVSQIFGSSSPSPNGFITTRSYGTVCPKDWEFYQARCFFLSTSESSWNESRDFCKGKGSTLAIVNTPEKLKFLQDITDAEKYFIGLIYHREEKRWRWINNSVFNGNVTNQNQNFNCATIGLTKTFDAASCDISYRRICEKNAK
The following text describes a protein:
Function:
Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
Subcellular Localization:
Nucleus.
Sequence:
MEEVKEVDYKERFTHPGGLPIHEKRVSRWDRKIRDVLPNIPVHIPPSLDEKYWDTLAIRIRYEELQYALGTHRLGLNTERDRTPSPPKQYNENQQEITREMRREEKLKNERLYVVDRAIEIYPSFRIPAELAKPSGKRTKKIYFPKDRPDTNFIGLIIGPRGDNQKRLEKDSGAKISIRGKDPKKLGKLSGYGDKDNEDSHVFITADTQEALDLACEEITKIISAPSEEINVLKHNQLRELALWNGTFREDRVYEVEQYESGVKCGFCGDSSHATCDCPLKKQKMSEHQLELERAFDEFMEKIQLQLIN
The following text describes a protein:
Function:
Major component of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Provides a framework for the nuclear envelope and probably also interacts with chromatin. Essential to maintain the shape and integrity of the nucleus, and for DNA replication. Involved in spatial organization of nuclear pore complexes. It is not a target for ced-3 during apoptosis, suggesting that lamin cleavage is not essential for apoptosis in C.elegans.
Miscellaneous:
MISCELLANEOUS: It is the only lamin protein in C.elegans.
Subcellular Localization:
Nucleus envelope. Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side. Note=Remains in the nuclear envelope until late anaphase in early embryos. Depends on mel-28 for nuclear envelope localization after mitosis.
Sequence:
MSSRKGTRSSRIVTLERSANSSLSNNGGGDDSFGSTLLETSRLQEKDHLTSLNSRLATYIDKVRQLEQENNRLQVQIRDIEVVEKKEKSNLADRFEAEKARLRRALDSAQDELAKYRIEYDAAKVEVKKLKPQVEKLERELAGAEEQALHAQSIADQSQAKQKTLQARNDKLVVENDDLKKQNITLRDTVEGLKKAVEDETLLRTAANNKIKALEEDLAFALQQHKGELEEVRHKRQVDMTTYAKQINDEYQSKLQDQIEEMRAQFKNNLHQNKTAFEDAYKNKLNAARERQEEAVSEAIHLRARVRDLETSSSGNASLIERLRSELDTLKRSFQEKLDDKDARIAELNQEIERMMSEFHDLLDVKIQLDAELKTYQALLEGEEERLNLTQEAPQNTSVHHVSFSSGGASAQRGVKRRRVVDVNGEDQDIDYLNRRSKLNKETVGPVGIDEVDEEGKWVRVANNSEEEQSIGGYKLVVKAGNKEASFQFSSRMKLAPHASATVWSADAGAVHHPPEVYVMKKQQWPIGDNPSARLEDSEGDTVSSITVEFSESSDPSDPADRCSIM
The following text describes a protein:
Function:
Probably involved in reactive chlorine species (RCS) stress resistance.
Subcellular Localization:
Periplasm.
Sequence:
MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLEDTIADIARKYNASSWKVTSMRIDNNSTATAVLYK
The following text describes a protein:
Function:
Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Contributes to the generation of inhibitory postsynaptic currents.
Subcellular Localization:
Postsynaptic cell membrane; Multi-pass membrane protein. Synapse. Cell membrane; Multi-pass membrane protein.
Sequence:
MHSLFLKILIYSLMQCVLGQAEFWDYDENVTQIEEDFKIDDVTRILKRVGNYNRNAYPLLDQDLATHVDIQMYIEGMSSFHAQSMDFQVDIYFQEKWVDHRLQHNNTKRILVKDPKLFGLLWHPDLYFANARTASFHDVTQPNFLVWIYPNGTVWYDCRISLTVLCMQDLARYPLDSQNCGLRILSYAYDEEQLIIRWNGGNPVEVNRGIRMPDMHLKHIKFYTKRDKYATGIWSSAVAEFHVDREITHHIIQSYIPTSLIVIISWFSFWLDVEAVPGRVSLSITTLLTLATQSSAARMALPQASDVKAIDVWMGTCMAFVFSAMIEFTVVNYCVRRKVRTKIKPRGLSEQVHDMVAQYREKKDKFNNGNCEISYEMALQPNEDNATVQRNFEKKEVREMNQASLFVRRSLLPTSKRKTIEDRINRVEENRKNAQKIDRYSRALFPLAFIIFNIFYWIYYLKYAGSNSPELLL
The following text describes a protein:
Function:
Part of a complex involved in cell-cycle-dependent transcription. SWI4 and SWI6 are required for formation of the cell-cycle box factor-DNA complex. The repeated element in the upstream region of HO (5'-CACGAAAA-3') is called the cell cycle box (CCB).
Miscellaneous:
MISCELLANEOUS: Present with 589 molecules/cell in log phase SD medium.
Sequence:
MPFDVLISNQKDNTNHQNITPISKSVLLAPHSNHPVIEIATYSETDVYECYIRGFETKIVMRRTKDDWINITQVFKIAQFSKTKRTKILEKESNDMQHEKVQGGYGRFQGTWIPLDSAKFLVNKYEIIDPVVNSILTFQFDPNNPPPKRSKNSILRKTSPGTKITSPSSYNKTPRKKNSSSSTSATTTAANKKGKKNASINQPNPSPLQNLVFQTPQQFQVNSSMNIMNNNDNHTTMNFNNDTRHNLINNISNNSNQSTIIQQQKSIHENSFNNNYSATQKPLQFFPIPTNLQNKNVALNNPNNNDSNSYSHNIDNVINSSNNNNNGNNNNLIIVPDGPMQSQQQQQHHHEYLTNNFNHSMMDSITNGNSKKRRKKLNQSNEQQFYNQQEKIQRHFKLMKQPLLWQSFQNPNDHHNEYCDSNGSNNNNNTVASNGSSIEVFSSNENDNSMNMSSRSMTPFSAGNTSSQNKLENKMTDQEYKQTILTILSSERSSDVDQALLATLYPAPKNFNINFEIDDQGHTPLHWATAMANIPLIKMLITLNANALQCNKLGFNCITKSIFYNNCYKENAFDEIISILKICLITPDVNGRLPFHYLIELSVNKSKNPMIIKSYMDSIILSLGQQDYNLLKICLNYQDNIGNTPLHLSALNLNFEVYNRLVYLGASTDILNLDNESPASIMNKFNTPAGGSNSRNNNTKADRKLARNLPQKNYYQQQQQQQQPQNNVKIPKIIKTQHPDKEDSTADVNIAKTDSEVNESQYLHSNQPNSTNMNTIMEDLSNINSFVTSSVIKDIKSTPSKILENSPILYRRRSQSISDEKEKAKDNENQVEKKKDPLNSVKTAMPSLESPSSLLPIQMSPLGKYSKPLSQQINKLNTKVSSLQRIMGEEIKNLDNEVVETESSISNNKKRLITIAHQIEDAFDSVSNKTPINSISDLQSRIKETSSKLNSEKQNFIQSLEKSQALKLATIVQDEESKVDMNTNSSSHPEKQEDEEPIPKSTSETSSPKNTKADAKFSNTVQESYDVNETLRLATELTILQFKRRMTTLKISEAKSKINSSVKLDKYRNLIGITIENIDSKLDDIEKDLRANA
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
Subcellular Localization:
Nucleus.
Sequence:
MDDDAETYKLWRIRKTVMQLSHDRGYLVTQDELDQTLEQFKEQFGDKPSEKRPARSDLIVLVAHNDDPTDQMFVFFPDEPKIGIKTIKTYCTRMQEENIHRAIVVVQAGMTPSAKQSLVDMAPKYILEQFLESELLINITEHELVPEHVVMTPEEKQELLARYKLKENMLMRIQAGDPVARYFGLKRGQVVKIIRPSETAGRYISYRLVC
The following text describes a protein:
Function:
Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases. It is not able to add an Araf residue to a terminal Galf.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MAARVLGQMVLAVLMASAVAGVAIAAIARVEWPAYNTSNQLHALTTVGQFGCLAGLFAAGLLWRRGRRTLARLGALAFISAFSVVTLAMPLGATKLYLFGVSVDQQFRTEYLTRLTDTAGLHDMTYIGLPPFYPAGWFWLGGRIAAATGTPAWEMFKPWSIVSITIAVALALVLWAAMIRFEYALVATAASTAAMLAYASTEPYAAIITVLMPPVFVLAWAGLRARTRGGGWAAIVGVGIFLGVAALFYTLLLVYAAFTLTIMALCVAVARRHIDPLLRLAVIAVISGAIALLTWAPYLLAAMRGEPADSGTAQHYLPDAGAELHFPMFSLTLHGALCMLGTVWLVVRARTSTRAGALAVAVVAVYAWSLLSMLTTLAGTTLLSFRLQPTLTVLLTTAGAFGFIEATLAIAHRYRPETSRRVVAAATAVGAIGAVTFSQDIPDVLRPDINVAYTDTDGTGQRADRRPPGAERYYREIDAKILEVTGVPRNQTVVLTADYSFLSFYPYYGFQGLTSHYANPLAQFDKRAAAIEGWATLGSADDFVAALDELPWEPPTVFLMRHGANDTYTLRLASDVYPNQPNVRRYHVELDSAVFDDPRFEVSDHGPFVLAIRKPGGKPETDGH
The following text describes a protein:
Function:
The exact role played by hoefavidin in the host organism is still obscure. Forms a strong non-covalent complex with biotin and 2-iminobiotin.
Subcellular Localization:
Secreted.
Domain:
The C-terminal segment plays a key role in the formation and stabilization of the octameric configuration, since the short afifavidin (lacking the last 5 amino acids) is only dimeric.
Sequence:
MNKVLAIVLTITVAGFAQTAFADDHAMSPDMKLLAGASNWVNQSGSVAQFVFTPSPTQPQTYEVSGNYINNAQGTGCKGTPYPLSGAYYSGNQIISFSVVWSNASANCQSATGWTGYFDFSGSQAVLKTDWNLAFYSGSTPAIQQGQDDFMQSVATVSESLLTE
The following text describes a protein:
Function:
Mitochondrial RNA-binding protein involved in mitochondrial transcription regulation. Functions as a protective factor to maintain proper mitochondrial RNA level during stress. Acts at the transcription level and its protective function depends on its RNA binding ability. Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation. As heterodimer with MTRF, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MAMASVKLLAGVLRKPDAWIGLWGVLRGTPSSYKLCTSWNRYLYFSSTKLRAPNYKTLFYNIFSLRLPGLLLSPECIFPFSVRLKSNIRSTKSTKKSLQKVDEEDSDEESHHDEMSEQEEELEDDPTVVKNYKDLEKAVQSFRYDVVLKTGLDIGRNKVEDAFYKGELRLNEEKLWKKSRTVKVGDTLDLLIGEDKEAGTETVMRILLKKVFEEKTESEKYRVVLRRWKSLKLPKKRMSK
The following text describes a protein:
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization:
Nucleus.
Sequence:
MMDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKNAEKGPPTAAATSAAAVAAAATGAPATSSSDGGGGGGCQEAAAEEKEQRRRPESSSSPESSSGHTEDKAGGSGGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
The following text describes a protein:
Function:
May contribute to the regulation of cell proliferation.
Subcellular Localization:
Cytoplasm. Mitochondrion. Nucleus.
Sequence:
LDAETFQEMLGKAIDIWKSENRRGIWIRCPTSHAHLIAPSTNYGFDFQHAEPGYCVLTKWLPTNSISRLPNGPTHQVGIGALVIHPRTGKMLAVQERNGPAAARKLWKMPTGLTDPGEDISSAAVRELKEETGLDCQFDRIICFRQAHGGLFNRSDMFFVCLCKLSPKYEQRLEEGGDIELLPQEEEILCADWIDMEDYAHQSVWKESPLYKEM
The following text describes a protein:
Function:
Negative regulator of effector-triggered immunity associated with the EDS1 resistance pathway. May localize its interactors to a microsomal membrane. May therefore negatively regulate RPS4 and SNC1 translocation to the nucleus. Contributes to the regulation of RPS2 and RPS4 protein levels and negatively regulates SNC1 stability.
Miscellaneous:
MISCELLANEOUS: [Isoform 2]: May be due to intron retention.
Subcellular Localization:
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Membrane; Single-pass membrane protein. Microsome. Note=Found in microsomes when interacting with SNC1 and RPS4.
Sequence:
MATATATSERFELAKHCSSRNWSKAIRVLDSLLAKESSILDICNRAFCYNQLELHKHVIKDCDKALLLEPFAIQAFILKGRALLALGRKQEAVLVLEQGYKSALQQTADVKQLLELEELLKDARREIDGILKSHATESPQETPAYHSEKSDEKSDKLDNHESGASSNGNSHESSSELGEQSKIVSFSKVASKASKQSDGNSDLCNGSVYKEKENGKCGSQINGYYESCKPCNGSDLHDNLAESSDRFGELSINGNKISIKSSKMSHKAEARCGISDESRKNKKYTIARISGTHSISVDFRLSRGIAQVNEGNYTKAISIFDKVLKEEPTYPEALIGRGTAYAFQRELESAIADFTKAIQSNPAASEAWKRRGQARAALGEYVEAVEDLTKALVFEPNSPDVLHERGIVNFKSKDFTAAVKDLSICLKQEKDNKSAYTYLGLAFASLGEYKKAEEAHLKSIQLDSNYLEAWLHLAQFYQELADHCKALECIEQVLQVDNRVWKAYHLRGLVFHGLGEHRKAIQELSIGLSIENTIECLYLRGSCYHAVGEYRDAVKDYDATVDVELDAVEKFVLQCLAFYQKELALYTASKVSSEFLCFDIDGDIDPMFKEYWCKRLHPKNVCEKVYRQPPLRESLKKGKLKKQDLAITKQKANILRFADLIGKRIQYDCPGFLPNKRQHRMAGLAVIEIAQKVSKAWRIEWRNSTKGTTKNGKKNRRRERTNILSQNRGGAGCSSSSFSETSTGYASLEDRSSGRSILSWQDVYSPAVRWRQISEPCDPVVWVNKLSEEFNSGFGSHTPMVLGQAKVVRYFPNYERTLTLAKSIIKDKLSVRSKKDKVIDLSKDEKIEKIMRAETCDELHNIVGEDFWVATWCDSTGSEGKRLEGTRITCIQKPGRLGYDFSIRTPCTPARWSDFDEEMTSAWEALCTAYCGENYGSTELDALETVRDAILRMTYYWYNFMPLARGTAVTGFVVLLGLLLAANMEFTETIPKGLQIDWEAILNVEPGSFVDSVKSWLYPSLKINTSWRDHTEISSAFSTTGAVVAALSTYND
The following text describes a protein:
Function:
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels (By similarity). Participates in control of cell volume in low-osmolarity conditions.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIAMIQHHESNISWMFIVDILQQFGLGIVIGLGGGYLLLQMINRIALPAGLYPLLALSGGILIFSLTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLKIGVRVAEEEAES
The following text describes a protein:
Function:
Involved in the biosynthesis of the floral volatile isoeugenol. Catalyzes the synthesis of the phenylpropene isoeugenol from coniferyl acetate. Phenylpropenes are the primary constituents of various essential plant oils. They are produced as antimicrobial and antianimal compounds, or as floral attractants of pollinators. Isoeugenol is a characteristic aromatic constituent of spices and a floral volatile compound.
Sequence:
MTTGKGKILILGATGYLGKYMVKASISLGHPTYAYVMPLKKNSDDSKLQLLKEFESLGVTIFYGELSEHDKLVAVFKEVDIVISTLAVPQYLEQLKVIEAIKEAGNIKRFVPSEFGNEVDRVRALPRFQAVLDNKKKIRRATEAAGIPFTFVSANSLTAYFVDYLLHPRQKSEQVTIYGSGDAKAVLNYEEDVAAYTIKAADDPRAANRVLIIKPPKNIVSQLDLVSSWEKTTGSTLKMTHISEQEIIKLSESINFPENIHASILHNIFIAGAQLSFELTQDHDLEASELYPNYNYTSVDEYLKICLVNPPKPKLATYAQPST
The following text describes a protein:
Function:
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis also has a role in the induction of peripheral tolerance (By similarity). Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (By similarity); [Tumor necrosis factor ligand superfamily member 6, soluble form]: Induces FAS-mediated activation of NF-kappa-B, initiating non-apoptotic signaling pathways. Can induce apoptosis but does not appear to be essential for this process; [FasL intracellular domain]: Cytoplasmic form induces gene transcription inhibition.
Subcellular Localization:
Cell membrane; Single-pass type II membrane protein. Cytoplasmic vesicle lumen. Lysosome lumen. Note=Colocalizes with the SPPL2A protease at the cell membrane. Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination; [Tumor necrosis factor ligand superfamily member 6, soluble form]: Secreted. Note=May be released into the extracellular fluid by cleavage from the cell surface; [FasL intracellular domain]: Nucleus. Note=The FasL ICD cytoplasmic form is translocated into the nucleus.
Sequence:
MQQPVNYPCPQIYWVDSSATSPWAPPGSVFSCPSSGPRGPGQRRPPPPPPPPSPLPPPSQPPPLPPLSPLKKKDNIELWLPVIFFMVLVALVGMGLGMYQLFHLQKELAELREFTNHSLRVSSFEKQIANPSTPSETKKPRSVAHLTGNPRSRSIPLEWEDTYGTALISGVKYKKGGLVINEAGLYFVYSKVYFRGQSCNSQPLSHKVYMRNFKYPGDLVLMEEKKLNYCTTGQIWAHSSYLGAVFNLTVADHLYVNISQLSLINFEESKTFFGLYKL
The following text describes a protein:
Function:
Catalyzes the synthesis of N-acetylaspartate acid (NAA) from L-aspartate and acetyl-CoA. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Sequence:
MHCLSPKMVCETKIVAEDHEAIPGSKKDSIIVSTSQMWPSLSGGPASGLPASGVGAEEELKKEPLYIREFHPKEQDVACRIFYDGIMERVPNTAFRGLKQQPLAQLMYVLLALLCFVVTKSLLLTCCVPVFLMGMRYYYSRKVILTYLNCALHTDMSDIEQYYMKPPGSCFWVAVLDGNVVGIVGARGREEDNTVELCRMSVDANYRGKGIAKSLGRKVLEFAVLNNFSAVVLGTTAVKVAAHKLYESLGFKHTGVVEHYALPGMTHSPLEKLFFQLRYHRYRLQLREE
The following text describes a protein:
Function:
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MADGVVSSAVHPNGHSPEFVFRQYRGRRAGIVKALTXDVEEFYEQCDPDEKALCLFGLPDGTWEVSQLPEEIPVQLPEPVCGINFARDVTPKKVWLSMIAIHSDAWLMSIAFYHAGRVSFDRVGREQLFRLINRLPTVYEAVTGSYERQAQTPNGSRKNKSSSQPPNQFTSNCKPVTPALPMPKEDYYADFNSWKVMEDRPMLKEEDGGKEGGGSEDQAITKCAGCQEIYSANDGHLWIGCDHCQRWFHGKCVGVTAEMANGIEDYMCPGCSYKATTKASDSI
The following text describes a protein:
Function:
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Tyr residues of target mitochondrial proteins (AMPylation). Involved in redox homeostasis by regulating the cellular response to oxidative stress. Regulates protein S-glutathionylation levels possibly by AMPylation of deglutathionylation enzymes such as glutaredoxins.
Miscellaneous:
MISCELLANEOUS: Present with 2430 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MGEKRTIIKALKNSAASHFIKKLTADTSLSSIQEAINVVQQYNATDPVRLKLFHTPRMVSQGAHFAFCLPTKKPHYKPLLLSQNALDEFNLVQDQDLEKILSGEKVYYSDSIFPYSTVYSGFQFGSFAAQLGDGRVVNLFDLKDKCSGQWQTFQLKGAGMTPFSRFADGKAVLRSSIREFIMSEALHSIGIPSTRAMQLTLLPGTKAQRRNQEPCAVVCRFAPSWIRLGNFNLFRWRHDLKGLIQLSDYCIEELFAGGTQFEGKPDFNIFKRDFFPDTETKIDEQVEKDETEVSTMTGDNISTLSKYDEFFRHVVSLNANTVAHWQAYGFANGVLNTDNTSIMGLTIDYGPFAFLDKFEPSFTPNHDDTAKRYSFANQPSIIWWNLQQFAKDLACLLGPEARDLELLLKGELNSVDDALEKTMIERVQKLVELSANEYKYVFTTRYAQIMSQRLGVDLDLEKCMSSTNLKDIEHAAEKAKEFCDVIVEPLLDILQATKVDYNNFFIHLQNYKGPFFIKDKSDTATLFGAFDEEYLGMFFNSKQLQQMAETEEAFAAGEKVFDANGELRLLNEKLQEIRNWTQDYLTLVPPTETAARASLAKKANPLFVPRSWVLEEVVDDLMYSQRDGLQDPSSELDTSALKKLYLMSVNPYDRTKWDVTLRPELETKWADLSHQDDAKFMMQASCSS
The following text describes a protein:
Function:
Functions as an E3 ubiquitin-protein ligase. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate.
Subcellular Localization:
Cytoplasm. Nucleus. Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Sequence:
MDEDETTYPEALRRLLIETPAAIWQLDDESAQCNNCGGPFTWFRRRHHCRWCGKLFCYNCCNSFAKLPVSSVSVDPTEDLIPQDMFIRDPDFLANDNDDDNDSQDSSWINVRVCVNCRQQLSELKELDLPYPITTCLNDDTTTRSNNQVIQSSCGNNLQRIEEPDDFVECPVCYAPLSSFKTLSERESHVANCLSNNSSSPRNMTEFLKHARRYISMQLSETSPCLGQECIICFEEFAAGDRVARIEYCLCIFHLKCYRDWLSTGAAGCPVHAATLHLS
The following text describes a protein:
Function:
Metalloprotease (By similarity). Plays an essential role in molting, a process during larval stages in which a new cuticle is formed and the old cuticle is shed. Required during ecdysis, the opening of the cuticle to allow the worm to escape.
Subcellular Localization:
Secreted.
Sequence:
MKSQACLKVCLALIGLVSIVSTAYIANDVVSDYAEVKELLAAFYRKHAKKYGHDYDPAAIQAIAENMDKSVKNDKTEATVNRKLWNEVFENDIILTLPQAESLLSESNSPRSRRQAHPDPRNFWPNLTISYEFYGGEETWRQLIRSAIRHVEQNVCFKFKENGGDRDGLRYYRGNGCWSNVGRVGGRQLVSIGYGCDSLGIVSHETLHALGLWHEQSRDDRDNFISIVADKITRGTEGNFAKRTAANSDNLGQPYDLGSVMHYGAKSFAYDWSSDTIKTRDWRYQNTIGQRDGLSFKDAKMINTRYCSNVCQRSLPCLNEGYTDPNNCGRCRCPSGYGGTYCETVEYTSCGGSLTASSSYKKIESGIVQPDANCVWRIRNPGGNVEVMFDQVNFQCADPCQSYVEVKYLSQKTSTGARLCCSLPSVIRSEGDDVIIILRGTPNTAVGWRGFTLKYRAIGGTPITPATVRPTYATTTRPYWTRTASGWIHIKNPPLYKPDGQIYTSDEQSAETKYSSEELYDPSTFLSPSSSSASPALLLPSDASPQRPSAQEHDLSQLSQNALTRPTPTTTVAPDTASWSAWGEWSACSQPCGGCGTKTRVRACYGGNQVCPGSNLDRESCNAHACAKPKKGMICNGRLLLPCDLLAKLNFGSNNYLNPKLKQSGFARSSTLPLPRISQRKPVFVNELEVHPPTERFLSSSTRRVKRQTANRFCEKRFIYQCPTALLTIQMEYKPDTQGTNDAYFQQYPECCSGYTPRRGVCYKN