lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Sequence:
MDKNIWTSRRRRGRSHHRSPALRQCDSSERYTSGASQSSQDSGHHDVECPSTSSSKAGESSVPDLPGFYFDPEKNRYFRLLPGHNNCNPLTKEGIQLKEMESRRLQLLQQEDKQKKKIARVGFNASSILRKNQLGFLNFSSYCRLSHELRVACMERKKVEIQSSDPSALASDRFNFILADTTSDRLFTVNDVKIGGSKYGIISLQGLKAPTFEVHMHENLYFTNRKVNSVCWASLNHLDSHILLCLMGLAETPGCATLLPASLFVSSHQAGTDQPGMLCSFRIPGAWSCAWSLNVQANNCFSTGLSRRVLLTNVVTGHRQSYWTNSDVLAQQFAVKTPLLFNGCRSGEIFAIDLRSPSQAKGWKATQIFHDSAVTSVQVFKEEQYLMASDMAGKIKLWDLRATKCVRQYEGHVNEYAYLPLHMHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPCPTSKANIPSVAFSPRLGGPRGAPGLLMAVQQDLYCFPYSSSCPDGLKEGRWEPSSVSKEDIL
The following text describes a protein:
Function:
Acts as a component of a SCF E3 ubiquitin ligase complexes.
Subcellular Localization:
Nucleus.
Sequence:
MSETRSKNLPPWEALVMVAHYLDPQTLALASCVSKSWCQAMSLDVVWRPLCSSSFPSLSNLKISYPSVPYHRLYATGLAAFKRRHNPPSKPRLSIDNIVFTIQLSTKGVPIFTIAEVASKMNNNQVFKFDVGVKHGSFKGIKGLEEMKVTWNVVLKGWEAIFTMMDWQGKLSCRAVEGWFSEELPCAGCCSSEVGSGIVADLKVDMEVEKVSVGILRVVDWRYVSIEDGLRYLQHFLLPCQCDGM
The following text describes a protein:
Function:
Facilitates bidirectional transport of amino acids. May act as a glutamate sensor that regulates glutamate-glutamine cycle and mTOR signaling in the brain. The transport mechanism remains to be elucidated.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MTAAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLWVGLGVLVVSTVTTLSVSEEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVAATGTSILKEANWLVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHRLDHGGHLEMRKARGGDHVPVSHEQPRGGEDAAVQEPRQRPEPELGLKRAVPGGQRPDNAKPNRDLKLQAGSDLRRRRRDLGPHAEGQLAPRDGVIIGLNPLPDVQVNDLRGALDAQLRQAAGGALQVVHSRQLRQAPGPPEES
The following text describes a protein:
Function:
Together with AlgI and AlgJ, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues. Acetylation of alginate increases cyst resistance to desiccation.
Subcellular Localization:
Periplasm.
Sequence:
MTRLHRKHRIALGLGLGLLLGFGGTTVQAAGDAALYEAVAPKGSTFVRLYNASNQEVSANVGSINLEDVSPLSSSGFEYLPAGQYSARVGSQNLPVNLSAEHYYTLVTQSGAAPLLVEEPAFKSKQKALLRVQNLSDKPLTLKTADGKTEVVKSVEPKGRGDREINPVKANLALFDGERKVADLKPISLARGEVVCLYVTGTANQLNPVWVKPPVKE
The following text describes a protein:
Function:
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. QCR10 has a role in CIII assembly and RIP1 stability.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MLSRFLGPRYRELARNWIPTAGMWGTVGAVGLVWATDWRLILDWVPYINGKFKKDD
The following text describes a protein:
Function:
Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
Subcellular Localization:
Cytoplasm.
Domain:
IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
Sequence:
MGKRFTEYSQFDLSQVNKDVLKKWDENQVFAKSMTERDGCPSFVFFEGPPSANGMPGIHHVMARTIKDIFCRYKTMKGYQVKRKAGWDTHGLPVELSVEKALGITKEDIGKKISVADYNAACRKDVMKYTKEWEDLTHQMGYWVDMKHPYITYDNRYIETLWWLLKQLHKKGLLYKGYTIQPYSPAAGTGLSSHELNQPGCYRDVKDTTAVAQFKMKNPKPEMAEWGTPYFLAWTTTPWTLPSNTALCVGPKIDYVAVQTYNAYTGEPITVVLAKALLNTHFNSKAADLKLEDYKAGDKLVPFKVVAEYKGADLIGMEYEQLIPWVKPVEVSEDGTWKVSGKGFRVIPGDYVTTEDGTGIVHIAPTFGADDANVARAAGIPSLFMINKKGETRPMVDLTGKFYMLDELDENFVKECVDVDKYKEYQGAWVKNAYNPVFMVDGKYDEKAAQAAESLDVALCMMMKANNQAFKIEKHIHNYPHCWRTDKPVLYYPLDSWFIRSTACKERMMELNKTINWKPESTGTGRFGKWLENLNDWNLSRSRYWGTPLPIWRTEDGTSEICIESVEELYNEIEKSVAAGFMKSNPYKDKGFVPGEYTEGNYDKIDLHRPYVDDIILVSEDGQPMKRESDLIDVWFDSGAMPYAQIHYPFENKNILDNREVYPADFIAEGVDQTRGWFFTLHAIATMVFDSVSYKAVISNGLVLDKNGNKMSKRLNNAVDPFTTIEKYGSDPLRWYMITNSSPWDNLKFDIDGIEEVRRKFFGTLYNTYSFFALYANVDGFEYKEADVPMAERPEIDRWILSVLNTLIKEVDTCYNEYEPTKAGRLISDFVNDNLSNWYVRLNRKRFWGGEFTQDKLSAYQTLYTCLETVAKLMAPISPFYADRLYTDLTTATGRDNVVSIHLAEFPKYQEEMIDKELEARMQMAQDVTSMVLALRRKVNIKVRQPLQCIMIPVADEEQKAHIEAVKALIMNEVNVKDIKFVDGAAGVLVKKVKCDFKKLGPKFGKQMKAVAAAVAEMSQEAIAELEKNGKYALNLDGAEAVIEAADVEIFSEDIPGWLVANEGKLTVALEVTVTEELRREGIARELVNRIQNIRKSSGFEITDKIKITISKNTQTDDAVNEYNTYICNQVLGTSLDLADEVKDGTELNFDDFSLFVNVIKD
The following text describes a protein:
Function:
Plays a key role in the correct positioning of the annulus, a septin-based ring strucure in the sperm flagellum, serving both as a physical barrier and a membrane diffusion barrier that separates the midpiece (MP) from the principal piece (PP). This positioning is essential for proper sperm motility and function. Interacts with CIBAR1 to form a complex which localizes to the curved membrane region of the flagellar pocket. By doing so, may provide stability and rigidity to the periannular membrane to prevent membrane deformation. This function is crucial for halting annulus migration at the proximal end of the fibrous sheath-containing PP.
Miscellaneous:
MISCELLANEOUS: 'Chibby' is Japanese for 'small'; the gene was so named for the RNAi phenotype seen in flies.
Subcellular Localization:
Cell projection, cilium, flagellum. Note=Localizes to the annulus at the junction between the midpiece (MP) and principal piece (PP) of the sperm flagellum.
Sequence:
MADSKMKWGQAWDSSLGTATTSSSSATGSPSPFQNIRVPDTRAPRVAHTTFTLEAFECLAASQAGRLWKQVRQFWVDHFSRRFSPRRPPLRHISSMSTFYLLDHRTRQAELGLNYGEPRTRLSDEAFVFRGGRWTPEGKRASARTPLPSSTIPAWKPQVQPIKSQVLLEENNYLKLQQELLMDMLTETTARMQLLEKKVDADNNPAAPARSWKRKMPKQRGAGVLIIQPRALESR
The following text describes a protein:
Function:
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
Subcellular Localization:
[Phosphatidylserine decarboxylase 1 alpha chain]: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain; [Phosphatidylserine decarboxylase 1 beta chain]: Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Sequence:
MKFRLSQHVPMFPPYSHAGHVHIHRRFFSWYAKQFPTTSQARASVSGGNSDSQGNAFLLPGATVATLLMLGALHARRLYDDKKVEDAREKGVEFEFQPDVKAAFLRMLPLRSISRVWGFLTNVEIPVWLRPHVYRAWARAFHSNLEEAALPLDEYASLRDFFVRTLREGCRPIDPDPYSLVSPVDGTILRFGELKGAGAMIEQVKGFSYSVSSLLGASSLLPIIAEGHTQDDSSTIEQESSQREKSKKSWWRISLASPKVRETVSACCVYSSNSLDCWTIQDILFPMKGLYYCVIYLKPGDYHRIHSPVDWNVLVRRHFAGHLFPLNERATRTIRNLYVENERVVLEGLWQQGYMAVAAIGATNIGSIELFIEPELRTNRPRKKLLHSGPPEECVYKPEGVGVMLKKGEEVAAFNMGSTVVLVFQAPTLKSPKNSNASEFRFSIRRGDRIRVGEAMGRWHDS
The following text describes a protein:
Function:
Involved in the signaling of vulval development by acting as a negative regulator of epidermal growth factor receptor (EGFR) signaling. Aids in phagosomal membrane tubule formation which is required for phagosomal fusion with endosomes and lysosomes. Also recruits rab-7 to phagosomes by an interaction with dyn-1. These are events leading to phagosome maturation which is a step in apoptotic cell corpse clearance. Binds phosphatidylinositol-3,4,5-trisphosphate.
Subcellular Localization:
Cytoplasm. Cytoplasmic vesicle, phagosome membrane. Note=Recruited to phagosomal surface by phosphatidylinositol trisphosphate. BAR and PX domains are required for the phagosomal localization.
Domain:
The BAR and PX domains are required for recruitment to the phagosome; The SH3 domain is involved in phagosome maturation.
Sequence:
MAQVKAEYDFQSQPNTGELSISAGEVLTVIRENIDGGWIEGRNVRGSVGLFPESYVTPYQASRPPPVLPPPLPPTSSGPPAASSRPFDDWGGASEVAAPPSYGAQHHHQPTPSVPEVTRSSYPSQNDDFDDEWTDEDDEQEPTRPNVQSSIGSNSRRDLSRSHSEHGGPDRGSNKVNKNINRFSNFVKSGVEAYVIGESKTTSQISERHEVVMNNGIIQWKPIQQYYTCIVDKPKKESKLKGLKSFIAYSITSSLTNIQRQVSRRYKHFDWLHEQLSAKYVLIPIPPLPEKQVAGRYEEDLIDHRKHILQLWVNKICRHPVLSQSEVWLHFISCTDEKDWKNGKRRAEKDEYIGGAFLNCITVPHQPLDPNNVDMQVERFQRSVKTSEEAMRVMQERMNMFQKVFAGPVKQNWQKMGSAFKTLQQSFEIDETVASRRLTEALAYTASEYHEIGQVFDAHTKNDMEPVLENLYSYKGTVQNVPDIIQVHKQAVQKFRDSEGRLSSAEAEKMKQRIDAMSYTVIAEVQHQTAEKVEDMKSTMGTYLKKQAMFYQEVATKLTSLAARYD
The following text describes a protein:
Function:
2-oxoglutarate-dependent dioxygenase essential for auxin catabolism and maintenance of auxin homeostasis in reproductive organs. Catalyzes the irreversible oxidation of indole-3-acetic acid (IAA) to the biologically inactive 2-oxoindole-3-acetic acid (OxIAA).
Sequence:
MESENSVPVIDLEDFPRQLSKLIWACEEWGCFRILNHDKILPVSLMAEMKEVVRALFDLPTEIKKRNKDVIAGSGYMAPSERNPLYEALGLYDMSCVEDVDEFCTQLDASPHQRETIKKYAAAINGLMMDILRKMSEGLGLRNVSFEDWPCQFRINKYHFTPEAVGSYGVQIHTDSGFLTILQDDECVGGLEVMKKSGEFVAVDPWPNTLLVNLGDIGTVWSNGRLYSAKHRVICKEAKLRVSIASFLLGPRDTAVEPPPELVNAEHPRIYVPFTFNDYRKLRLSTKLQAGEALDLMRTNLILNHDKILPVSLMAEMKEVVRALFYLPTEIKKRNKDVLVGSGYMAPSEKNPLYEAFGLYNMSCHEDLDEFCTQLDASPHQRETIKKYAAAINGLMMDILRKMSEGLGLPNVSFEDWPCQFRINKYNFTPEVVGSSGVQIHTDLAFLTILQDDESVGGLEVMKKSGEFVAVDRWPNTLLVNLGDIGTVWSNGRLHSVKHRVICKEAKLRVSIASFILGPRDTAVEPPSELVDAEHPRMYVPFTFTDYRKLRYSTKLQAGETLELMRTNL
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MAEEESDQEAERLGEELEAIVRPPPGPAGLSSRDYCRRFCQVVEDYAGRWQVPLPQLQVLQTALCCFTSASVSFPAECEHVQYVLSSLALSFFELLLFFGKDEFYEEPLKDILGSIQECQNLLSRYGNVNLELVTRIIRDGGPWEDPVLQAVLKARPASPDLVNKYLSSENPLFFELRARYLIACERIPEAMALIKSCINHPDISKDLYFHQAFFTCLYMSPLEDQLFQEHLLRTDCKNGIDIICNTEKEGKTMLALQLCESFLIPQLQNGDMYCIWDLIFIWSKLQLKANPSKQVFVDQCYQLLRTATNVRVIFPFMKVIKDEVEVEGLQICVEICGCALQLDLRDDPNTKCLIYKTIANFLPNDLEILRICALSIFFLERSLESYYTVEHLYKRPDEEYNERTSSVQNRVRFELLPILKKGLFFDPEFWNFIMIKQNCAALLRDKSAVGFLNENTLEHASGNTEKAVEQQPLDEDLTPANDLSSGELDPEDVSRALSGGHGNAKKNLALLGASKVDHNVPRHRCVLCNREFLGGHIVRHAQAHQKKGSFSCVICGRKFRNRGLMLKHLRNHVKKIQRQHLAALEQEDLEIPIVEEMNCPDASVSFENGKCDSSKEQEMETAVASNDENKEEEIPEQVAKIISDPVCEPEDVVKNGSHASSLNDASEPPLNLETLPEYEEDDDDPNQESLVLNKVNGVLCTPTDLDVMDQQGNFKCPANGCVRIFKKIRFLNKHARKAHPADFKVQQHIMKWNKGKCRFCQRKFADSQHFIDHLKRHIYPNVFFCLHFNCNQRFKLSTELAEHMKSHSAFKAQCHFPECCELFEELPLLYEHEAKHYLNQTPESSAETSENNIFDALSESHLDHQEKDLTGSEKETVDLPVPTWKSRKDSTEPKTYIQSVEKKTHGIVQNGSENSSDVAAPDLSLLDQKMPVVEPNSENSSVVNDRLVNGHSELEQTSLVSTDAALKGETSVARTENGSVLPNVEDVPQEQSAPVVSQSPFKPNLTTENTSYGLIVTKPYVRPLPPSYLDERYISMPKRRKTLTDKVDNHSEQDKVCNKSVERFRCGNCLNIYCNSEALEAHLAQKKCQALFGFDSDDESA
The following text describes a protein:
Function:
Converts fumarylacetoacetate to acetoacetate and fumarate. Involved in tyrosine catabolic pathway. Catalyzes the final step in the tyrosine degradation pathway.
Sequence:
MDLKSFIEVQPDSHFPIQNLPYGVFRTAPDLPPRPGVAIGEYVLDLSEIASAGLFDGPLLKNSDCFNQPNLNKFLSLGRPAWKEARATLQKLLSSTEPTLRDNEALRLKSLIPLKQVNMVLPVAIHDYTDFFSSMHHAKNCGTIFRGPVDPIVPNWFHLPIAYHGRASSIVISGTEIVRPRGQSRPVGDSPPPFGPSAKLDFELEMAAVVGTGNLLGKPVDINEAEDHIFGLVLMNDWSARDIQAWEYVPLGPFLGKSFGTTISPWIVTLEALEPFKCDAPKQDPAPLPYLTEKESKNYDISLEVRIRPAGESDAHIVSKSNFKHLYWTLPQQLAHHTVNGCNLQPGDLLGTGTISGPEPESLGCLLELTWNGEKPLELANGLHRKFLEDGDEVVFTGQCEGDGYTVGFGTCAGKILPSAEEKDLINYKS
The following text describes a protein:
Function:
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
Subcellular Localization:
Cytoplasm.
Sequence:
MKLQTTYPSNNYPIYVEHGAIDHISTYIDQFDQSFILIDEHVNQYFADKFDDILSYENVHKVIIPAGEKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGATGDFAGFIAATLLRGVHFIQVPTTILAHDSSVGGKVGINSKQGKNLIGAFYRPTAVIYDLVFLKTLPFEQILSGYAEVYKHALLNGESATQDIEQHFKDREILQSLNGMDKYIAKGIETKLDIVIADEKEQGVRKFLNLGHTFGHAVEYYHKIPHGHAVMVGIIYQFIVANALFDSKHDINHYIQYLIQLGYPLDMITDLDFETLYQYMLSDKKNDKQGVQMVLIRQFGDIVVQHVDQLTLQHACEQLKTYFK
The following text describes a protein:
Function:
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.
Subcellular Localization:
Early endosome. Membrane; Multi-pass membrane protein. Recycling endosome.
Sequence:
MNDTQGAPTQTHTSQVAGITWIQPTSTTNTPSHKHVTFELSFLGSSSRGWRNSESHQLPFPSNFPAHLLPPSHTSPLAPSSFLVLGESLCAGKPPGFSASLSTFRKTWSPPFSFPECGSSPADSSLKTGSPWGQCRKWSWGSDRQWAWGKHFLNALPTPWPCPGLMPSLVPGAYLGTTATDRTTPAHLSARPAPSSIMGNCLYPVADDNSTKLAIKEDFLIDFPEDYYPDYNETDVEAAAPCHSCSLLNYSSLPFFILVSILGILASGTILYALLRPLFRWQLYQDRSTLVQLAVGSALFSIVVPILARGLSGALITSLCHLAHLVAYGSAFAQALLIGYHACLGPQLGAGQVPGLRLGVTVGLWGVAALLSLPVVLGSDTSQGLCTVTFSGEWETLRYIHAAACFAIFVLLPLGLLGTKGLKTVLGRAPCPWVDVLWVWFIFWWPQGMTLGLDSLVRSKAIVVSTCPAQQALDMLLDVAEALAILHCVATPLLLAWVCYQATHTSPPSLPLPTTQTSHLDTFGGKS
The following text describes a protein:
Function:
May act as Rab effector protein and play a role in vesicle trafficking.
Sequence:
MTKVPQGFDFSFLNEEEARKILQVLERNEELRRAEKDRISKLQKTKRDIRWLQGATGEWFEEIQRKKFCNETDVNQMLKPPLTYRLQKGMAKNDPMELQTPRSKSLINQKPSVSSRMSFRSSFASLFSFRRPAKETLKLQSPRPNRCDERVRPSASVRGTASAKIYNSPVGNQPVASVFVPKPAIMREESGMPPPWDASLLESEFFQVLDDLDNKLAQEQSSGLMNTRVPFNYGSRTQFKLSHRNSHGHSTGRQQNYHSETSNMSIYNILRPGTPREGFKTFSPRTKTIYDMYRTREPRVLKEDFMQKNAFGSASLCFDSRQRSASPATGSFTARSLHFPADTQNKSSFTPVRHQQSPKRTPLSSIIWNRSDASRHRQNQEESLGVQAPMDIDPEEQYVSPRCFQESRRYEMCHSQNAYQSYPLNVPVANAMSPDTLENSENMPFYRQSNPFARSFFSSTFRQSREQRFGQNSFWSRQEEYSSWSDFPQSRGPFPSSDKDFEMFSVEANRAPSVCSQGVPSQHWRSHSSGHGTYVFRGREDSHCWRSDFQTSPLESMDTSHVNENQHPPHFVTPVGFSITDSSCHLQSSRLDSQQGYFPVEEAVDEDPYLCGKAQTPASSFRTPFPLSPDDGRESQSSSFPDSTATLQKIIPNKPDFLPIRNCTEVPVACSHSTDSLSLTDTQPNIPVTETNSEKDMDVSVSKDEQLNKTGQKSRPTGLPQYVLHTVISNDLPDFQNAHSRDSAQNDRYGFNAPATERSRRSPRVFSRKGTSQIHTTQRDQSNKLSKNKCFGGDRTLDSAASPPFIQESGTATSLPSPNQGCHQKTGSNEESSNTIKNSHWCFESTANQKSQPSREPALLDLEQSLSTHSTNDSKLAPGHSISRAPLHVASDAPQESFLDARLVPSTTVFSRSLSDQDPGQEQREEKDKATKSQDNQLAVNSTDNQESHDSPALPHDAVHCHPYSPFKNGRGKGRVRRRVSCIEKLTKTERAAAPTREGSGCAEDQRSIKDPELSTVYCTLPRKPASFLIHSRQQESKGTVASVRNGPLPFQIKNKAEVPTGKSTSDKPSSPESVSDAANAVSGTPKATKKMTDMKAIRSASVRKGPLPFLIKRAISCPSGEPCSLAESDDRQKSSVLGMDASPVIPRPGGRIFNSLEGEPSFRESAFSEKELAQEHTGKDRELRAPRMGLFNPSKKTPERLCATGSGKESGRALHKFKTTSMFSVSGDEENVNCLEVVSIYYTLPRKPSKKFCSLLQQYTQGTDSLRDAFQGETEALPNALEIDELNCPAQVQSGIPPPQDPKMQVDSAPCCLSHSPESKDVSQLPDRETSKSTLEEMTSVGPDVSLHREEPTTKEISPSNVSKTAIDDSLSREKREKELLRQILRAPLLHQEKGAGKEHTKSHQQPSKGGNSGPSGLPSRSEDNDENSQTRRDSGTCAGGMASGNGQYPWRDHMAAVVGDRSSRSQPRETSGTTGSDCQNPTDKMLSDSESQAFALTPALCKLQLAEEAQPGGAGLQSEASQAGSQETNTAEMRKVEDEEHMLTRDQTLLPRGNNKNKTNTDETKDRYSGKHRLAAISKASKRIPAKDLSPRKHVATIFSQSESESGFRRLSLYRPEDNPLSPEPTVKATESTDESSQMNVDKSETLLQETTVSSPGPPGQPCHQKSASILQPHLNGSPGVLETPPKSEGSKTQISGELGAPAQLTLTSPLEKGAGHQQRLSPPFPLEPTQKSTINSHCQLRHRSAPSPESEPEPHLYRSKSLKNFNVQSDLLCASHPPKARGRHFSENTSIDNALSQLSLEDGSFPNSGYNRRFKSSSELPASYESESWTSYSNRTRGPKSTSSISRPIDYGIFGKEQQLAFLENVKRSLTQGRLWKPSFLKNPGFLKDDVLNASNLSQSELVNSPAGQAPEDGVFPSEPLNIYKDDPVEPLVSDWDTDTTTDDEYYLDEKDKESEL
The following text describes a protein:
Function:
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum.
Sequence:
MLPSLHDILDQHTYKWIFFGGKGGVGKTTTSSSFSVLMAETRPNEKFLLLSTDPAHNISDAFDQKFGKAPTQVSGIPNLYAMEVDASNEMKSAVEAVQKETGSAADNDAESKSEGDMFGGLNDLITCASSFIKDGTFPGMDEMWSFINLIKLIDTNEYSTVIFDTAPTGHTLRFLELPETVNKVLEIFTRLKDNMGGMLSMVMQTMGLSQNDIFGLIDKTYPKIDVVKRISAEFRDPSLCTFVGVCIPEFLSLYETERLVQRLAVLDMDCHAIVINFVLDANAATPCSMCRSRARMQNKYIDQINELYDDFNIVLSPLRHDEVRGIANLRDYAETLIKPYRFCWSANPDPSSAK
The following text describes a protein:
Function:
Endogenous secreted peptide that acts as elicitor of immune response and positive regulator of defense response. Amplifies the immune response triggered by flg22, the active epitope of bacterial flagellin. Acts as a negative regulator of root growth.
Subcellular Localization:
Secreted, extracellular space, apoplast.
Sequence:
MRRVSWSTVLIVVVMVSLFFVEHVVVPAAAGRVLTEKSGDGSATMTVEKMKSTVDSWFQRLASGPSPRGRGH
The following text describes a protein:
Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Sequence:
MMITNRTKKKLLTTRTRTRILSYQTTTTRRRLNNHPTRTRTRTRTSTISNQPSIKETSRATFRPPLPPTTSTTTGRQSKNHQPKIDYSQFNNGFNSSRSQDQLSQLTVSIAIGDLQRAQSIILEIERSLGYLRTKAFFQTNNTLNELLKLNKHFNEPLVQRDPNDHHLPTLNQIIHPSIFSSLLRRTLVQAIKQESLGNLNHAHILQSHLFHWLLNFKLNGPHWAQVDHHLMAGVLKGVLFLKDPIYSVLDYMPWILPSSADQTKKYQPPSTTSLPPTLLNVLDSITFMISQTKSFFGSLDKHQALERIKEQAMKEGRQDVLDEVEVVERHWNAGPSTSPNPASLDNPSGVNSDLPIPLHPVRKPSKSTDDPSKEREIPMRLSHLLSNVSTIPESATQSFTTGYDRQMVLEYAGYDSAEAEWFEGHKEIKERGIGFTNGEGGQVLQAWMWEWWAALKEWFDELEVDDQSGNILDAKKETVATDLRFIKVLQNSLIAKVAVVEVIREMGNSTINDGAKSIGLFIALGKAIENEWYAQTIKAIPELNQKLLAAIKTLNQENLDATASRSVDHTVRKIWKSELKNYQADLQAIHGDNFDWTIQQRSKVGALVMRGLLETSKITRSTVLEDGSVYEEVQPAFYQTTQYFDGKRVGVTKMNEAVAERLDLDPANVSLHPRYLPMVCRPMPWTHPKNGAYLVHGAPLMRTRDSPEQALHLLEAHRFHGLENVYKALDKLGNTPWNINRPVFDTMSTVWNQGIQLAGIPIRDPHLNLKPDQIEKLFFSPPPSSTTPASDDEHHDQLENQSSSSSQLENPRSEGEKKEIYRSLLASRRSAYGQRCSVNYQLEIARAYLNETFYFPHNIDFRGRAYPIPANLNHIGDDISRGLLKFAEEKELGEDGLRWLKIHLSNKYGNDKASLDDRAKFIEERLELVFDSADRPLEGKRWWLESEDPWQTLAGCMELTAALRSPDPTAYRSSLPVHQDGSCNGLQHYAALGGDIDGGKEVNLVPGEKPGDVYSKVAVEVAKLVDFDAANGHDIAKALKGHIKRKVVKQTVMTTVYGVTFVGAREQIKRQLKDLGVIPIPNLYISAAYVATLVLRSIGEVFKGAVAIQKWLTIVARLVSKSIPPERVESLTTSPSTAKKQKEGEGAEGVAKTKKPRPVKRKLPGSSSAAHDPDVEVELMTSMTWTTPLGLVVCQPYRAQNRTQIKTVLQTVYIADPFEPAQADSRSQASAFPPNFIHSLDATHMMLTALACQDITFASVHDSYWTHASSVDHMNSKLRESFVRLHTTRILDNLVQEIKHRYEGYMVPKNALTSRMINELKAMGIDRFNSPSSSSTTTSTTASSSTSSASTSTSDTDTQTETDSNSNKGTITGNSSGKFLELNQLIPPLPPRGNLNIQDVIKSKYFFA
The following text describes a protein:
Function:
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
Subcellular Localization:
Secreted, extracellular space.
Sequence:
MDLRLCLCLFILGSSWCCAARELAVLNPLITETEDVSVLQINNLEELRQVQPLEEVNGNEQLCTLCEEYTAKALNYMDNNKTQTEIIDRLHKSCSKMRFYKEECAILVDYYAPLFFLQINKMKPENFCQQFGLCEQVVIISQVLSGKNCDLCHKVVTEAESKLKDPDTRLEILELLLKACGAIKPYAKKCKKLVFEFAPVILINAEQFLEQNDICAILHACEPAVDKEQASPMKQTSLHSAS
The following text describes a protein:
Function:
Responsible for the transport of C4-dicarboxylates.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLFSIQLLIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQPGKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTILCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLGNVTFDGKHLEFLDLLSITIPSTLLGILAIGIFSWFRGKDLDKDEAFQKFISVPENRQYVYGDTATLLDKKLPKSNWLAMWIFLAAIAVVALLGADSDLRPTFGGKPLSMVLVIQMFMLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLGEMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLAAIQFDRSGTTRIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL
The following text describes a protein:
Function:
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Subcellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Membrane, clathrin-coated pit.
Sequence:
MNLPRMLLLLLTISITSSFQMQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLLQEDTKVSFSPSFLMVWSRNAAEVRDSCGGSEQASWVKTAFLLLVSTERKFWITLNKDMLRKIKMQAPL
The following text describes a protein:
Function:
Involved in pre-rRNA processing and required for biogenesis of the large (60S) ribosomal subunit. Required for proper development.
Subcellular Localization:
Nucleus, nucleolus. Note=Associates with 60S pre-ribosomes.
Sequence:
MGRKRKHSETEAPAPVKKSDEPAPDRPKRTLLGWKDKSEGEAEKAKALTSSGFKNKEKVLVTCSRRISFRYRSLMLNIVSLLPHCKKDSKVEAKSSKGATLNELIELKNSNSCLFFECRKHKDLYMWMVKSPNGPSVKFLVKAVHAMEEMKLTGNHLKGSRPLLTFSSNFDKDAHWKLLKEMLTQVFGIPKEHRKSKPYHDHVFVFSIVDEHIWFRNYQISVPHNESDKIAKGGLDKMTLIEVGPRFCLNPIKIFAGSFGGPTLYENPLYVSPNQIRALEKRNKAGKFAKKIKAKTRKKMHELSNPLEPDEFADMWKDDE
The following text describes a protein:
Function:
Upon overexpression suppresses small RNA (sRNA)-mediated RhyB-silencing of multiple RNA targets; overexpression leads to partial loss of RhyB sRNA and other sRNAs. May act via Hfq.
Sequence:
MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGLVATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNEFGYAAVVTLGDPALYSRFGFELAAHHDLRCRWPGTESAFQVHRLADDALNGVTGLVEYHEHFNRF