lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication.
Subcellular Localization:
Nucleus.
Sequence:
MDSQPTAEEAALRREIVKTFQIHAFELKKEAVKLCVKLFLEHDKDTRKKWTNKMIELLKKQTLQSSLISEELIRETFRQCKSKGSQDAGKLLNVFDAFSLHAYDFEPELGKMVLRKATPTLAADSSSFSHAARQRFLLVKQRAARCASLKNFKFTTCEILSASTKTLKSVVVLGMLTQQKADCYHIEDLSGSIEVEFKEDTKFHHALFHEHSIAIFEGNFENSVLKVNEVAMVPVESAETTRKELSSNENWFGGEDKIAFRCSERLRSALAKQEDTSIIFLSDVFLDDMKTMRALNKLLIGYKDQPPIAIVLCGNFCSRPRQTDTIDLLDRGFRYLANQLQQMKKEYEKTQFIFVPGPDDPFVDLVLPRPHLPSLLFKHVSPIISATFASNPCRIQFASQEIVVFRNDLIKKMCRHSINSITVESISSRYARSILSQAHLCPLPQHITPILADFSHCLSLHPLPDLLISADRFETFQEKVVGTETIVSNPGSFARSNYTFHVYYPAQNRIEASQIPNSELIDEFVPY
The following text describes a protein:
Function:
Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS).
Miscellaneous:
MISCELLANEOUS: Was identified as a high-confidence drug target.
Subcellular Localization:
Cytoplasm.
Sequence:
MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQRGARLLARAAAEFTRILTGVDIHPGAVIGARVFIDHATGVVIGETAEVGDDVTIYHGVTLGGSGMVGGKRHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVVKPVPPSAVVVGVPGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEALGGGPQAAGVIRPPEAGIWHGEDFSI
The following text describes a protein:
Function:
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MTAITLLASFSFSLLGYFLTSSLIPRLSATLISAGLKGKDLLKGNSTGGGDFHHHPRSSSSSSKTTTANTPEQPGSDQHQFIPESTGLIAGSVYVLILCLFVPIPYYTHLLPDSFLPGSTAFFTSGPASPGPGPAGDAQAARPPFPLSSLTAHLASILSLLSAVFLGFLDDVFDIRWRFKLPIPIIASVPLLTVYAASSGSTDIIIPHIFGLRALFGVAMTNGLLSIGPLYYLYMSMLSTFCTNSINILAGINGVEVGQSLIICLSIICNDLLYIHLDLAELGLPHRLSFGFANGSKALEDRHLFSLCLMLPLFAVMLALIKFNWYPARAFVGDTFCYFAGMAFAVVGILGHFSKTLLLFFIPQILNFLYSSPQLFGILPISRHRLPSRDPVKNVLKPSIVLFKTPLPASPTLKSSLLKAFETLRLIQLVRNKHNLVVGCSNLTLLNLALIWLPGLNERQLSSTILAFQFFSNFFIGFFIRYFLADLFYDPRLR
The following text describes a protein:
Function:
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MGEFRESSSPLRTPSHSPNQSLPRPNYVHGDFSPSNNRFSFNSSSDFSLSSSFSNGFYSSDDSSASPPFNGLIPNYNHSSPPFTYHHHDKSVNGDDFGLCNDLYRMKIKEDVVQEDPLASFLETNHTGSSLDPLYFSHYEPRNNGGFFHTQKEPFDTWFNNDQTEDKRDMFGHQTQDSIANSRQFGWPSYPTSNSPYINGQEMLGLGMNLGGGLTREHSAYYRTPTTTSSDMLPLFCQGAQASKVSEPFTSDESFFMEPQRIGVTRGLMSDPTEICHTSLPNVCDIQGYVYLMAKDQHGCRFLQRIFDEGTPVDAMIIFNEVISHVVELMMDPFGNYLMQKLLDRLVETIRTGKQVSMVKSALRPGFLDLIKDLNGNHVIQRCLQCLGTEDNKFIFDAATKFCTEIATHRHGCCVLQKCIAYSMRQQREKLIAEISRNSLLLAQDPFGNYAVQFVIELRIPSAVAMMLAQLKGHYVQLSMQKFSSHMVERCLMHCPESRPQIVRELVSVPHFDHLLQDPYANFVIQAALAATKGPLHASLVEVIRPHSILRNNPYCKRIFSRNLLKK
The following text describes a protein:
Function:
Essential scaffold subunit of the transcription coactivator SAGA complex. SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription. At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B. SAGA interacts with DNA via upstream activating sequences (UASs).
Subcellular Localization:
Nucleus.
Sequence:
METNFEDSKSLDEPVLHDIAIALLKNDYWSLYLSPEQKRKYISILNDTLLWNRFINVIEWDKLCDEKDSNGSNDDEEDDLDITTLFRCRCMIFDAKINPALFDLSSTSSGSIEHVDHQNISLEASLAEEEERKKGDAKKSEATGRQLFDDDDFDESDAEDSSKATITLDLQKDKSLRKSIIDLKSVDIDDMDTSGFAAIESNKALSNISFNYVYYTLENDSENINEVKKFEDEEDTSTPNTSSFQNNSSSLDLSDNLSLNSKFGSLTSSFKYLLQYLEGNRSKINATDADVKQLLSDVKKNKSKWANDQRIGQEELYEAAEKVVLELRSYTEHSLAFLTKVSKRDAPDYYTVIKEPMDLGTILRNLKNLHYNSKKEFVHDLMLIWSNCFLYNSHPDHPLRVHAQFMKDKSLELINLIPDIVIQSRKDYDDSLIEAELESDEESTAETSKHVTSKKTSSRGGQTQQAVEVHTDANSPEENNTPVTKKEVETSKPPAVSGSTPPVNEAAVIESSNTLEKEPLSDVATEYWKIKTKDIRESHILNNRRILKSLQFIETELPMIRKPTAMSAFIDREVAYGSIDCLPMDKGDFEPIMKLDTTPLLEYDVGSGVPMTAGSVLETESEEDLYFRDYSLFEINRNTPGVPSLMYKNIAKMQEIRKLCNKIQTVRQLQLPQPFYYEHHKSHVPFANNEPILLDIPQNYDNMSSFKPLAHDVLKKLCTIILFHAGFESFQMGALDALTEIAADYMAKMGAVMDQYLIYGKDKSQQEIVGQTLGELGVDDVNDLISYVYHDVERQSVKLLEIHQRLQRHFVELLRPALSERNDEEAIFNQNGESFVTGNFSYETGDDFFGLRELGLDRELGLDSLSVPLHLLQSRLRSNMSWQPEATIKGDQEYAPPPKYPPITAESISNEIGLIQGFLKKNLEEFGLDELLEDEDIRPRSKPPRPRLPPNGKITTGRKRIASSVFLNQSLRKKRCLKENEQGTEVTTLPEE
The following text describes a protein:
Function:
Mediates the nuclear export of actin and profilin-actin complexes in somatic cells.
Subcellular Localization:
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Sequence:
MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQVGAWRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLHQPIPILDVESEYVCSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDTRARKMASVNGSSQNCVLGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFVVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCGEAHRQNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNSIIDASAQRLTDKAQVLVCRALSNTLLLPWPNLPESEQQWPLRSINHASLISALSRDYHSLKPSATAPQRKVPLGDTKVIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRTTMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQKNVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL
The following text describes a protein:
Function:
Low-affinity inorganic phosphate transporter. Mediates proton-driven uptake of soluble neutral metal phosphate (MeHP04) complexes. It can use Mg(2+), Ca(2+), Co(2+) and Mn(2+). Activity impacts bacterial growth in low Mg(2+) conditions. Is also involved in Zn(2+) uptake, probably via formation of a ZnHPO4 complex. Can also transport arsenate. Involved in the uptake of tellurite.
Miscellaneous:
MISCELLANEOUS: The Pit system in E.coli K12 consists of two transporters, PitA and PitB, which can transport phosphate independently of each other. Both proteins may have contributed to the kinetic values and substrate specificities determined in earlier studies.
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIYTRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLLAAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLIVSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSAIGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQHPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKGMLTTDVESYDKLSLDQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVALALGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVLSSSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAVLLSGGLYWLSLQFL
The following text describes a protein:
Function:
Functions as a component of the nuclear pore complex (NPC).
Subcellular Localization:
Nucleus, nuclear pore complex.
Sequence:
MVIHTIIPKSVITGQLRSKWDRKNGIAVFPGSSDFSNSVKDERAEFNIWEVQLDPKRYEGLARRVISESHDHCLNFYMGDRVKMGLLEWIVWHFPQVDELHKKMILEAHVIREHRNYWPTIYGYVVSGRMNSAVELLNVSVKDSNDKSDSSPEYVLKWRHWQQECRNSLTGDIQQHRHLHRLCRSSTGNVKLATDIYKSRKVKIISDLLQILCGDEKVLQELSNEGVIHTWYHLLVVHILFRNPTTKVYDLHYSIDLSLELFYGDKSRLGKLDEVISAIFLLDTVRVIKEASYGTDLREYLLLEYGSSLMSARYYLEQYISRIPLDSEKKTRKVLHVCEKYGLSTDLADICREECMTAIRREKLGSAISWALYVKDVTLINYIVDCYMSAYIKDGNADRLAIVDDIGAAITLTGQLAFLGKFREFHTFCNTGNLVDAASILVLLMVDGLASKKYWWMLLLDAIPLFETEEILFDSDQTYELLRCLTEIELSLRGPGDSWSNRLTLKQQVHKNSEVLHDALNTIRIALARNLARAHINEEQ
The following text describes a protein:
Function:
E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme ubc2/rad6 to form the ubc2-rad18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MNELDATDPSDWNQTKIPSLKGLDSSLRCLICHEYFRAPLITSCSHTFCSFCIRDYLREHPMCPACRAPEQESRLRKNTILEEILESFKVIRPTLFEFLKVENVPKPVLQAPETVIAQDSASGDEEWEDDLASNSSPASIAKKTSRDSKKRKREDLVHCPACSNLVPHNQINQHLDSCLNSPSSPSSSSSPYKNKDNSKSNSLLSFKTDDDSITKRRLRSFNSADELPLKDRVRLPKLTYALLSESKIRSKLSEMGLPTDGHKQLLQRRHAKWVTLYNSNLDQKQPVSKRNLIRQLIDWERVQSKSIGVEKEKLGGGDWEKAYAEDFADLINRAKQSTTNKNDSLRNTAVESSTEPSTSNGFPATSVSPPLTIDLTNSQTGSDGPQS
The following text describes a protein:
Function:
Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems.
Subcellular Localization:
Periplasm.
Sequence:
MNKLLVSLLLTLGLTGLAHAAGDAAAGQAKAAVCGACHGADGNSPAPNFPKLAGQGERYLLKQMHDIKDGKRTVLEMTGLLTNLSDQDLADIAAYFASQKMSVGMADPNLVAQGEALFRGGKIAEGMPACTGCHSPSGVGIATAGFPHLGGQHATYVAKQLTDFREGTRTNDGDTKIMQSIAAKLSNKDIAAISSYIQGLH
The following text describes a protein:
Function:
Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
Subcellular Localization:
Mitochondrion matrix.
Sequence:
MRSQVLSLYKLLHRTSQKTFLGDAKALEAAQLRIRDEFNSNKDVSDPKALKKLLKTGQDVQLLLKTSVAQGIHKEDGRYSLRIHEHLLREDNAPFPCDKDKSNR
The following text describes a protein:
Function:
Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.
Subcellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein.
Sequence:
MWAKCQERIFLEHGHTARKMLSTQIPEYFGSERREDLLQGCSMPSPPLDVEARLLCADPFLLSLPATLYPAAQARSLSSFAVMAAATPLSPEGLLLPKGGAGKVEQLGAEIEEDDDDELDETLGERLWGLTEMFPDSLRSAAGATFDVSLSIAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQMQQRQVSFILTLLSFNSAVLVQQFINLLQRVPFIYGSPVLSLA
The following text describes a protein:
Function:
Inhibitor of the serine/threonine-protein kinase pak4/pak5 (By similarity). Acts by binding pak4/pak5 in a substrate-like manner, inhibiting the protein kinase activity (By similarity). Required for the proper migration of neural crest cells during embryonic development, probably by inhibiting pak4/pak5.
Subcellular Localization:
Nucleus. Cytoplasm.
Domain:
Contains 2 Inka boxes (also named iBox or inca box). The Inka boxes bind and inhibit PAK4 by binding a substrate-like manner.
Sequence:
MLCLQESGDCLRDQMRYMMRSLQDLKHLRRSCVAPPVGPPVRLRACKQLIAQRERRARLRISDASEASSYDSACCLSSSLEEEESASDPSAVSSPSSERSLEFDSGYSEASWQDEGVVLRRTKNIRVSSTACLRTNQLSNTRARPKSTSDACLESWTSFETASDPEDWTTSLLTRGRNRQPLVLGDNSFADLIHNWMDLPECPEQTELKHSSGRSFAKDFLVNIKRRIAGFSRSADGRRKSSDVTKLSKSIVPTKRLSCQIDVQHKMPFFYKSHTGLNELDTDYYQFSALMKSGSRTPIVCNDIIGYI
The following text describes a protein:
Function:
May be involved in spermatogenesis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNLINFNHYQDYVDSFITIQDTRYLGNKEIQRNLIQNACGKNCLGNLLTREQFYQRKEKELVLLKPRGLRGLQLFGDYLNNKDEVLQQFANREKKLLEKQISTVVYLVMRSKKGLEISSFLDLEQSLRESRFENSTSCVDWRAIFEGRTKLRPSNLHLSYFDWHQNRVSFNNSDNFRVLNKRPHSLLLKHVGDHKIFCVNASCDCEHSKNVSRKTYFSPIYGYVIFFDHIIRRIN
The following text describes a protein:
Function:
Dephosphorylates nucleoside monophosphates such as the 5' and 2'(3')-phosphates of deoxyribonucleotides in vitro. Also catalyzes the dephosphorylation of coenzyme A (CoA), pyridoxal-5'-phosphate (PLP), riboflavine-5-phosphate (FMN) and nicotinamide adenine dinucleotide phosphate (NADP) in vitro.
Sequence:
MKKVIAIDMDQVLADLLSDWVAYINTYDDPFLKEKDILCWDIKKYTNTNNNVYRHLDYDLFRNLNVIEGSQRVTKELMKKYEVYVVTTATNHPDSLKAKLEWLTEYFPFIPHSNVVLCGNKNIIKADIMIDDGIHNLESFEGMKILFDAPHNRNENRFIRVMNWEEIERKLL
The following text describes a protein:
Function:
Digests double-stranded RNA. Involved in the processing of ribosomal RNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes pre-scRNA (the precursor of the signal recognition particle RNA). Probably also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (Probable). Involved in degradation of type I toxin-antitoxin system duplex RNAs.
Subcellular Localization:
Cytoplasm.
Sequence:
MSKHSHYKDKKKFYKKVEQFKEFQERISVHFQNEKLLYQAFTHSSYVNEHRKKPYEDNERLEFLGDAVLELTISRFLFAKYPAMSEGDLTKLRAAIVCEPSLVSLAHELSFGDLVLLGKGEEMTGGRKRPALLADVFEAFIGALYLDQGLEPVESFLKVYVFPKINDGAFSHVMDFKSQLQEYVQRDGKGSLEYKISNEKGPAHNREFEAIVSLKGEPLGVGNGRSKKEAEQHAAQEALAKLQKHHTKQ
The following text describes a protein:
Function:
May reduce intracellular freezing damage during winter by hydrogen-bonding to the lattice of the nascent ice crystals, thus modifying the structure and/or propagation of ice crystals.
Domain:
Contains 6 A-type repeats and 11 B-type repeats similar to those found in maize, rice and barley dehydrin and rab proteins.
Sequence:
MENQAHIAGEKKGIMEKIKEKLPGGHGDHKETAGTHGHPGTATHGAPATGGAYGQQGHAGTTGTGLHGAHAGEKKGVMENIKDKLPGGHQDHQQTGGTYGQQGHTGTATHGTPATGGTYGQQGHTGTATHGTPATGGTYGEQGHTGVTGTGTHGTGEKKGVMENIKEKLPGGHGDHQQTGGTYGQQGHTGTATHGTPAGGGTYEQHGHTGMTGTGTHGTGEKKGVMENIKDKLPGGHGDHQQTGGTYGQQGHTGTATQGTPAGGGTYEQHGHTGMTGAGTHSTGEKKGVMENIKEKLPGGHSDHQQTGGAYGQQGHTGTATHGTPAGGGTYGQHGHAGVIGTETHGTTATGGTHGQHGHTGTTGTGTHGSDGIGEKKSLMDKIKDKLPGQH
The following text describes a protein:
Function:
Probable GTP-binding protein that may be involved in cell development.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MQESDVFHNQLRVEMLKKEEDEVENNSEKKKAPGIDMNKVNLIKTRDEDIIAENIKAELKEEEKENMKVEEEEIKEEEEKKEKENYPCMQIIDQEGIFADENQKDRITFEEFIQENTKFKELGFNYNMLSILGPQNSGKSTLLNYLFDTDFAVLNEKNGRQRTTRGVWLGLVGDRKDIIIMDLEGSDGSIREDDLSFERKISLFSLSVCSVLMVNIWSHDVGRYGASNMSLLKNIFELNLQLFQKEDSPKTLILFVIRDRDQRKPFENTKSVLLEDIMKIWESVARPECFKRAPIDKFFDLEFTSLPHFKHDKELFIQEAKELKKRFDCKNQNTYFRPIYNKEIPADGLALFTKQVWSAIKSNKDLDLPSQKEMLARFRCDELIENIFNEFEKEIEEIKLQHSEKHIFNNFKIFCDCLYDKKMKEFMNVASKYLDRVVKEKADLLSEKMLNEISYLFQTQMTLAINYIKTMLTTSYFTLKNQYITEQSSLFDPTKYAGYAEQMDDFNSTIKNEWEKISTQSVPSNIENNFEIEINTLDRFINKLYEIGRRDLIEALMTHFKKHLQNIMKPLLLPLFEQSNQNMWEQVRKVVIETTSQNLQELENGMINSLKMNKDDVEKKLNELQVYIIDAVRSTILERPGFVSNLMENKFISIFRLDDEGLPKKWKQNEDLSKPFFKAKEEAEKILDLFSYIRMDPKDDELSFISINPATGKKMIIEEPENGTIDQTKVLFSLSERLSIYEGFQNMAESNFIRAQQELAAITVHSKTPMWLILLIAFLSFDNIVYVFKSPTLLALTLIIIGIIYSLNKIGYAYLIDSVISYILSISWSSVLYLIQDLGLFKNLLPKPEAPKRKRPQKKTQDDKPKSSILLTHKKQPSVMGDVTMDNIDSLNSFDDAFKLVSQDEKPIRKPLHPLPKRETQSMKVMPMSASFTKSQSMFIKRNPTTTSSLNKIKEANEF
The following text describes a protein:
Function:
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
Miscellaneous:
MISCELLANEOUS: Individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes, fliC and fljB.
Subcellular Localization:
Secreted. Bacterial flagellum.
Sequence:
MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
The following text describes a protein:
Function:
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MKISVKTLKGNHFDLEVSPADTVLNVKRQIEDSQGKESFPCSQQLLIHQGKVLKDETTMEENKVSENGFVVVMLTKAKTGAGASPPSSSGTTQAPAPVAAATPPAPARSPATPSPPTPATPAPTSAPATTTGLSAPASTYGQAASNLVAGNVLETTVQQIMDMGGGSWDRDTVVRALRAAFNNPERAVEYLYSGIPESAEMRPVGGRSPAVAGVPAATPAAPAQAAPAGGPNAAPLDLFPQGMPGMAGGGGAGALDFLRNNPQFQALRTMVQANPQILQPMLQELGKQNPALLRLINDNQAEFLRLINEAGAEGAEGDILGQLAGAMPQSINVTPEEREAIDRLEGMGFERTLVIEAFLACDKNEQLAANYLLEHAGDYEDA
The following text describes a protein:
Function:
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Subcellular Localization:
Secreted, cell wall.
Sequence:
MRPFIKSYSSHFIFFIICFSSLSVDPRADNVDPQLINVPLPAFKSSLEKTKELVQNVASTMSHMHAGEDYENSTVVVISYCEDLLNETADVLDWSLSTIDDLKADVVSHMRTWLNISQSKEKICVDTFQNMIDSNVAESLRQMTKSIDEVLGMIQVQQQHHLHRHNSTAAPGSDPALSWTADVTVSQDGSGKFKRIMDAIAAAPSHSQKQFVIFVKKGVYKEYVKIDKTKTNLVLIGEGMSVTTISGDRSNASGWATMKSATFDVRAEGFLAMNIGFENTAGPSKGQAVALSSGSDRSVFYRCKISGYQDTLLVLSGRQFYRECTISGTVDFIFGYGTAVFQHSRIIPRKAIKGQQNTITANGRLSEDSSGFSFQFCRIEADSDLVGNVNSTKTYLGRPWGKYSRTVFIKSFMSNIIRPEGWLEWSGENNLDTLYYAEYKNYGPGASVAGRVKWPGYHLISEADSFAVDKFIGGKSWLPSTGVPFKADL
The following text describes a protein:
Function:
Essential for thiamine biosynthesis. Bifunctional enzyme that catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP and condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MFTFPNFLIDYPQICTTFSSKQTGRQGFDQFGALTLKAIMPEEKSLTITNDSNNKKTPHVLTVAGSDSGAGAGIQADLKACAARGVYCSTVITAVTAQNTLGVQDVSILSEESVAAQLKSVLSDMRVDVVKTGMLPSITMVKILLDSLKQYPVQALVVDPVMVSTSGDVLAGPSILDTFRKDLLPMADIVTPNLKETSALLGGIQLETISDMRSAAKSLHDMGPRNVLVKGGDLPSSSDAVDIFFNGKDFYELRSSRIQTRNTHGTGCTLASCIAAELAKGSSMLSAVKVAKRYVESVLEYSKSINIGNGAQGPFDHGLKLKRSVCNSSRMQVFEPSDLFLYAVTDSKMNKKWGRSITDAVKAAIEGGATIVQLREKEGETGEFLESAKACVEICRLHNIPLLINDRVDIALACDADGVHVGQSDMPVATVRALVGPDKIIGVSCKTPEQALKAWGDGADYIGSGGVFPTNTKANNRTIGLDGLRDVCLASKIPVVAIGGINLGNAKEVMELGVVNLEGVAVVSAVFDRECVAEETRKLHDLLKESVVEKVMV
The following text describes a protein:
Function:
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.
Miscellaneous:
MISCELLANEOUS: Present with 6540 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Sequence:
MKFDNDSEKQVFDKLKKAIPGIIKEKCAGYDELYGYKLNPEGLTQEEVDKYYDEKIADRLTYKLCKAYQFEYSTIVQNLIDILNWRREFNPLSCAYKEVHNTELQNVGILTFDANGDANKKAVTWNLYGQLVKKKELFQNVDKFVRYRIGLMEKGLSLLDFTSSDNNYMTQVHDYKGVSVWRMDSDIKNCSKTVIGIFQKYYPELLYAKYFVNVPTVFGWVYDLIKKFVDETTRKKFVVLTDGSKLGQYLKDCPYEGYGGKDKKNNLTKQNVTNVHPTEYGLYILQKQIIEDVE
The following text describes a protein:
Function:
Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
Subcellular Localization:
Cell outer membrane; Multi-pass membrane protein. Note=One of the very few enzymes located there.
Sequence:
MSKQRARPLMLIALAAAPLAHAQEIAPQPASPQACTSVTSDAARLACYDQALGYTPQAVQEADAAAQLAKQAAKSEDTRKISRVGDFFRADGQDQPKEEAVANAGRGSLLDRRWELAKDSKLGTFQLRGYKPVYLLPAFWTSDTNRTPQSPNPANSVSTPQQLDSAELKFQLSFKTKVVEDLFGDNGDIWMGYTQSSRWQAYNSDASRPFRETNYEPEAMLVFRNNYSIFGWKGRMSGISINHMSNGREDPLSRSWNRVILNIGLDRENWALTLRPWFRIKEDRADDNNPDIEDYMGRGDATLVYNKDGHEFALIARHSLRGGDRSHGSVQLDYGFPITNLLRGHVQVFDGYGESLIDYNHKATYVGVGVSLLEWF
The following text describes a protein:
Function:
Involved in osmoadaptation.
Sequence:
MTNQTIQEALGHGQGNDLGNSDGHRIEYVETIEAYNKWAEVYDTDGNFLQALDTFEMKDLLPRFLCLVQTQTNGKSNMTPGEQVLKLVDLGCGTGRNTLQLAKSAPKEAQIIGLDASPGMLEVAEGNLKAQGVMGTVDERRVVLGVYDLLSPRPESLPVSLRGEARASGAISTLVLEHIPLDKFFEGAARLIRPGGYLLVTNMHAEMGAISQAGFVDVTSGKKIRPTSYAHEVGNVIAAAERAGFEIVPLNGAEKVRERRVNEEMVALLGSRARKWVNVVVWFGLS
The following text describes a protein:
Function:
Integral part of the sensory system that mediates food signaling, providing the neural basis for the regulation of food response; coordinates larval foraging and social behavior changes during development. Required in dopaminergic (DA) neurons that innervate the mushroom body for satiety to suppress appetitive memory performance; a key factor in the internal state of hunger in the brain. NPF neurons coordinately modulate diverse sensory and motor neurons important for feeding, flight, and locomotion. NPF/NPFR pathway exerts its suppressive effect on larval aversion to diverse stressful stimuli (chemical stress and noxious heat) through attenuation of TRP channel-induced neuronal excitation. NPF neural signaling system plays a physiological role in acute modulation of alcohol sensitivity in adults, rather than a general response to intoxication by sedative agents. Activation and inhibition of the NPF system reduces and enhances ethanol preference, respectively. Sexual experience, the NPF system activity and ethanol consumption are all linked; sexual deprivation is a major contributor to enhanced ethanol preference.
Subcellular Localization:
Secreted.
Sequence:
MCQTMRCILVACVALALLAAGCRVEASNSRPPRKNDVNTMADAYKFLQDLDTYYGDRARVRFGKRGSLMDILRNHEMDNINLGKNANNGGEFARGFNEEEIF
The following text describes a protein:
Function:
Cobalt chelatase responsible for the insertion of cobalt during anaerobic cobalamin biosynthesis. Can catalyze the insertion of Co(2+) into either sirohydrochlorin or precorrin-2. It is not clear which is the natural substrate in Salmonella (Probable).
Miscellaneous:
MISCELLANEOUS: In the absence of Co(2+), can act as a precorrin-2 ferrochelatase since, in conjunction with a uroporphyrinogen III methyltransferase such as CobA from P.denitrificans, it can complement an E.coli cysG deletion strain. However, this complementation is easily inhibited in the presence of low concentrations of exogenous cobalt, a result that can be explained on the basis of a higher specificity for cobalt over ferrous ions.
Sequence:
MKKALLVVSFGTSYHDTCEKNIVACERDLAASCPDRDLFRAFTSGMIIRKLRQRDGIDIDTPLQALQKLAAQGYQDVAIQSLHIINGDEYEKIVREVQLLRPLFTRLTLGVPLLSSHNDYVQLMQALRQQMPSLRQTEKVVFMGHGASHHAFAAYACLDHMMTAQRFPARVGAVESYPEVDILIDSLRDEGVTGVHLMPLMLVAGDHAINDMASDDGDSWKMRFNAAGIPATPWLSGLGENPAIRAMFVAHLHQALNMAVEEAA
The following text describes a protein:
Function:
Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Subcellular Localization:
Mitochondrion membrane. Nucleus. Secreted.
Sequence:
MVSPWRRVLMLATKLAPVPGPAVCQARRHASRGSFGWMSKNPKQKQQGAVFEDDHDMDAVEVKLDSIISEERRRQKAAKFHIIKRKMNTPGAPQRKLSWDAIEQIRYLKQESPEEWTLQRLAEGFSVSPDVISRVLRSTFTPPAARKLKQDAKVSPSSGPQYLKDGKAEQSRLQKSLTPSVLLPSANTSHSALKTLDTKQTGLTPSAGHITLSKQTAVLNVAPEYQDRLESKGEMDVNDDVEFEEEWDGVILTDEELEKITQTLHEKPSPVEQRGRDFFDSEGNFLYRV