lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
dsDNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance. FANCM-MHF promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork (By similarity). Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Sequence:
MNDDEDRAQLKARLWIRVEERLQQVLSSEDIKYTPRFINSLLELAYLQLGEMGSDLQAFARHAGRGVVNKSDLMLYLRKQPDLQERVTQE
The following text describes a protein:
Function:
Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of Atg13 and Atg1. The Atg1-Atg13 complex functions at multiple levels to mediate and adjust nutrient-dependent autophagic signaling. Involved in the autophagic degradation of dBruce which controls DNA fragmentation in nurse cells.
Subcellular Localization:
Cytoplasm, cytosol. Preautophagosomal structure. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resulting in the formation of an autophagosome.
Sequence:
MSAQRLNAAERDLEKFIKFLVLKSTQVVVQSRLGEKMQTQCNPLAGSDWFNIAVQDHPEVLDETKRALNLKTGESILQRLPLCVEISLKTTEGDQMVLEVWSLDLLQPQNGASPATNDLNPEGQTLKAAHAIYNRMGIMLKSLISLTRTTPAYKLSRRQCPDSYGIFYRIYVDRPQVHTLGEGHKHVKIGQLSTIVGSLVMSVAYRTKLTISPTAAQSESNTIMLKSDHFRPATDANTPGNQQQTQNGTVVAKKLGLGALNPAQGTADRRFIDIEKPLRPGAFTDMGKLKQYTEDDFVLPETPPFEWLLRGRGSVESLNRLDNNSVASVNISNNNNSTQDSKFNQISNLNNNSAGFKSFEKNSENSVSPIKSLLIPASATATYRHHSEPSLQPPPDDDNLLKELHFPFASPTSHVNDLAKFYRECYHAPPLKGLNELQAEISSISSTPPASSGSGGVAACGPTAAATAIATSSADASAMDDLSRQLEQFETSLEDYDKLVSQFGLTGSSSTGSRSSGGLQMSN
The following text describes a protein:
Function:
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MRSNSIFTKEIDSEAVKKSSNLRPPSTGSSNSNGSDTASPKKKKKGFFRSLFGSSSSGSKSCGSPFTRIWLEYFEVSLRKNDVDHFRPGYWILDTNIDFFYEIMLRQVLLKRPKEESQQIYLLRPAMVFFLAQAPNPLEIESALPPAMFDASFIFLPINDTNECGIESGSHWSLLVVSVEKGLGWYYDSMSNGNTNDCNLAIKNLGILLKKEFRVRHMKTPQQINDCDCGLHVCENTRILMYRLLQKPYVPKVDMNLDHSVVDSVRLRKALMEVITSLLAAYGSKVPKPSETHTDPEKDKKIFSKICKTEELLELPTLSAVTSDSAQPHSLPASMPSSQPQSRSESLPLTHPNSEPNPKLDSQPNSSPVRRPSLIKVKTASTSVLPTSILQRPPSIVPRPETAAIQHTQQSIEIH
The following text describes a protein:
Function:
Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers.
Sequence:
MAVSLTRKDLDAMRFLNGEVPTSITLAGTDFLANGHPILTEVPSNIVATPSPYSFPDNTKNNSTADHGCFVGFDVGEPSSCHVVPIGKLSGVRFMSIFRFKLWWSTHWVGSSGREVQYETQMMVLDKSDLGRPYVILLPIIEGSFSSSLQPGIDDNVDICVERGHESGQGTSGDIQASSGEKPTRHSGQIRLVHLGCLFSLRTSERCVGRGQGPGCPPGMLIIDDGWQSICLDDDPIDNEGIDRTANGEEKPYRLVKFQENYRFKDFESTKTPSNKGMGAFVKELKEEFKTVKDVYVWQALCGYWGGIRPKFSGMPESRIVKAHASPSMLKTMKDFAGLHSHLESVGIDGVKIDVIEVLELLSEDYGGHVELSKAYFKALTASLRKHFNGNGVISSMQQASDFFFLGTETIALGRAGDDFWCIDPYGDPTGIFWLQGCHMVHCAYNSLWMGNFIHPDWDMFQSHHPCAKFHAASLAISGGPVYVSDFVGEYNFDLLKKLALPDGSILRCQHYALPTRDCLFEDPLHDGITALKIWNLNKYSGVIGLFNCQGGGRCPHSRRNKSAPEFANPVYQSKKLKLMKSSEQMEVALEPLNYELLTVSPVAILPKKQIQFAPIGLVNMLNSGGAIQSLAFDGDENLVRIGVKGRGELRVFASEKPWACKIDGVPVEFGYDEQMVRIEVPGLNSPLPPMVEYFF
The following text describes a protein:
Function:
Involved in leaf development regulation.
Subcellular Localization:
Nucleus.
Domain:
The conserved PP2C phosphatase domain (250-651) is interrupted by an insertion of approximately 100 amino acids.
Sequence:
MGNGVTKLSICFTGGGGERLRPKDISVLLPDPLDEGLGHSFCYVRPDPTLISSSKVHSEEDTTTTTFRTISGASVSANTATPLSTSLYDPYGHIDRAAAFESTTSFSSIPLQPIPKSSGPIVLGSGPIERGFLSGPIERGFMSGPLDRVGLFSGPLDKPNSDHHHQFQRSFSHGLALRVGSRKRSLVRILRRAISKTMSRGQNSIVAPIKSVKDSDNWGIRSEKSRNLHNENLTVNSLNFSSEVSLDDDVSLENQNLQWAQGKAGEDRVHVVVSEEHGWLFVGIYDGFNGPDAPDYLLSHLYPVVHRELKGLLWDDSNVESKSQDLERSNGDESCSNQEKDETCERWWRCEWDRESQDLDRRLKEQISRRSGSDRLTNHSEVLEALSQALRKTEEAYLDTADKMLDENPELALMGSCVLVMLMKGEDIYVMNVGDSRAVLGQKSEPDYWLAKIRQDLERINEETMMNDLEGCEGDQSSLVPNLSAFQLTVDHSTNIEEEVERIRNEHPDDVTAVTNERVKGSLKVTRAFGAGFLKQPKWNNALLEMFQIDYVGKSPYINCLPSLYHHRLGSKDRFLILSSDGLYQYFTNEEAVSEVELFITLQPEGDPAQHLVQELLFRAAKKAGMDFHELLEIPQGERRRYHDDVSIVVISLEGRMWKSCV
The following text describes a protein:
Function:
Transcriptional regulator. Component of a feedback loop involving atfs-1, atgl-1 and hlh-11. Binds to the promoter of the atgl-1 lipase to negatively regulate the expression of atgl-1, and thereby promoting fat oxidation in response to mitochondrial stress and mitochondrial respiration in the intestine. In addition, functions with atfs-1 to maintain lifespan. May have a role in fertility and in positively regulating body size.
Subcellular Localization:
Nucleus.
Sequence:
MVRSDSAEEDQIIIDDGFDLTEEDEEMMSSGTGALPVTIADWNSVTNARMAPPSIMSAASAFDLTASGMQNSLRSVLPTSTIGHAPMLANRSLSQPAPLSPTSLDPDRRSRMRRQIANCNERRRMQSINAGFLALRALLPRKEGEKLSKAAILQQTADMVHQLLGHKGEDIPDGGEPKKLKLEEDHHDADHQAQIAHLQTILETERAARKALESQVIQLRELLQMTTTSSQASSPVTPRSNGSGGFTLPSSYASSALPTPLRESPERKPSFQDTTSTPLSLLTLNGSPTSSESLASQRIFHPPPTLPSLETTVIRPTPLPPISVEISSPSLSTPSPLTAAPIIFSTAVPTQSSILFQTAAAAVTSAMSTGNSTPVALPHHLQGHNSAFVSTQPSLTLSQSMQTIVEAIRHLEGSHFIPTSPPPTSQTSLVR
The following text describes a protein:
Function:
Involved in trafficking and recycling of synaptic vesicles.
Subcellular Localization:
Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Early endosome. Golgi apparatus, trans-Golgi network. Late endosome. Membrane; Multi-pass membrane protein. Recycling endosome.
Sequence:
MQDTEKRHFSNVKYHRIQRTDDGFIDIQFQKTLTRIPKKAIALATFLFVMGSTLIVMSSFIFTGFIDDKYYDSRWPLLVLGSLMFIPGVYHVRIAYYAYKKYPGYTYDDIPDFD
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNWKTPSKKIYDSADLKNFEKSIAFEKLQKTLQQIILSVENHKIPPGILNVDIVTRPGRIGSIPLPSLIEPTTTTTTRENKIGPSNGNVEILIELFQYLNKLIDETPPLKGPTRFGNFACRDWHDKIDIIPILKKFKFPQELSSSNNSSSKSNIDGFLLESSYYLLNSFGSKIRLDYGTGHELSFLAFIGSLIEFKILNHPTTTEEINGKEILIIFANYYDLVRRLILVYNLEPAGSHGVWGLDDHFHLIYILGASQFINDKLAPIVQRSLSSQVINSCKLTNFYINAIAFIFRLKTGPFNEHSPIIFDIHNKVFSWTKVRQGLIKMYMVEVFNKFPVLQHFWCGEVLYPWKDHQGNDLPVNEKEETELDKPPETTLNSTTTTTTTTKVSSSTSKIPFTPAPWANTTTTHAVPRNTRNTRNPRS
The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence:
MSSAHQLRVLKLYRHSLKNLLSWTVDRGMYRQKAMELRARFEATRFEKNIVKATQLVEAGEAELDEIKHPNPYVGRRLNPAWPAHSVSPWVFLCANGHAVAFRSPHIIGRYQMGA
The following text describes a protein:
Function:
Monitors brassinosteroids (BR) responses and homeostasis, particularly in the root and hypocotyl in darkness. Promotes flavonoid biosynthesis.
Subcellular Localization:
Cytoplasm.
Sequence:
MEAKLEVTGKEVIKPASPSPRDRLQLSILDLYCPGIYVSTIFFYDLITESSEVFSENLKLSLSETLSRFYPLAGRIEGLSISCNDEGAVFTEARTDLLLPDFLRNLNTDSLSGFLPTLAAGESPAAWPLLSVKVTFFGSGSGVAVSVSVSHKICDIASLVTFVKDWATTTAKGKSNSTIEFAETTIYPPPPSHMYEQFPSTDSDSNITSKYVLKRFVFEPSKIAELKHKAASESVPVPTRVEAIMSLIWRCARNSSRSNLLIPRQAVMWQAMDIRLRIPSSVAPKDVIGNLQSGFSLKKDAESEFEIPEIVATFRKNKERVNEMIKESLQGNTIGQSLLSLMAETVSESTEIDRYIMSSWCRKPFYEVDFGSGSPVWVGYASHTIYDNMVGVVLIDSKEGDGVEAWISLPEEDMSVFVDDQELLAYAVLNPPVVA
The following text describes a protein:
Function:
Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.
Subcellular Localization:
Periplasm.
Sequence:
MRVTRFLAAAALGLMSTLALADNADQNIRKTLQALQPDLPIDSIASSPLQGLYQVQLKGGRVLYASADGQFVMQGYLYQVKDGKPVNLTEKAESQAIAKAINGVPASEMVVYPAKGQAKAHITVFTDTTCPYCQKLHAEVPDLTEQGIEVRYMAFPRQGPQSAGDKQLQAVWCAKEPTKAMDAMMNGKEIKSSECKNPVDKQFQMGQMVGVQGTPAIVLANGQLLPGYQPAKQLAKLALEAK
The following text describes a protein:
Function:
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Does not accept 4'-phosphopantothenoylcysteine as a substrate.
Sequence:
MKYCNSRLNTCFQGKTSIYIRLSHKIEGIQGSSFRPKWAWKENTLTFVLPWKEKLIASSVVTSLHSSPRSPTSPPLTTSSAPPSNPYLYYVLELFSVDLISLMAIVKDSVAYSNISPPNSHGAVVLGGTFDRLHDGHRLFLKASAEVARDRIVIGVSDGPMLSKKQFADLIAPIEKRMHDVKEYIKSIKPELVVQVEPIIDPYGPSIVDENLEAIVVSKETLPGGLSVNKKRAERGLSQLKIEVIDILPEESTGEKLSSTTLRRLEAENMSCRFGRDVMKLISYLRLLVLMDALSDFSTVPFYTRRNLYVLDIAYVSGEAFIRLLSKWIVYLSCNQRVTFCRYSISHPSDARVNMRVQTTRLKLDLLNPYRFGKQASP
The following text describes a protein:
Function:
Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MCGVQISLNKCAEEAGKGTFSIQIADLMEKMSRTPGVVYVPEHSKERLSFNATDYRSKYEFTWPETAKDVLMKASVDRTPDDIRLVRSLMRGLYSFRKYSRNLQDLICKVIRYAKYGRRRVVIRKGHPGFSFYFIFSGMAGVTLEEDEMNAFVKKEVNILKKGASFGEIALLKDSRRKATVVCLENTEFLVVDSDDFFENNLHLHIQQDFEYRMNFMSHLDLFSTWTSESIEEISDMGRMEEYCNESLIVKDARDTDWLFIVTKGRADVLKLVDLAQLYMSKQDEEEEVMQVSRKAKVLKSAFAWNDDVSSKLTKIPQHQQYQQHQQPQSDPRFPWMTGGDGHEQPQKNGKKLDVPARPKTTGQISSRTRNHIADNAHADTAHGNSRSKSATVRLKVPSDKLDGSGDEGTNEHQSNGVYRSNQSRASSANHRRRTFSEPTEEMPTLPNHIKLGLETIKAPGVEAGVYIQVDALRSGDFFGIQGIKGEMPHLSLVSHGCEVIRISMSKFREFADDETLAKVNKLLPTYASGLELWRSFQKQNKWRNFKNGVITDVMRHAHQSDQAAIVERAGPRSRRSVTSDWVTNTWSRRSSMGGESSEVRNTPLPKIMTSAVERGSGPRSPRPRRRGKSAGVSNASTSRPGSRALTASRPPSTRVSDSRPPTRHSMSNHDLRILENRRSSVPASRFVSASQSLNNQQMARTLSAVGGAMSSGGEKRYNSQQSMPHLNIPDLANFTKPTFTRSRSWRELKS
The following text describes a protein:
Function:
Plays a role in nonsense-mediated mRNA decay.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSGPGQDSEPEAKVLLIKRLYRAVVESVHKLDVIIGSKSSYREVFKPENISLRNKLRELCVKLMFLHPVDYGRKAEELLWRKVYYEVIQVIKTNKKHVHSRSALECAYRTHLIAGVGFYQHLLLYVQSHYQLELQDCIDWTHVTDPLIGRKKPVSASPKEMEWAQMACHRCLVYLGDLARYQNELAGVETEQLAERFYHQALSVMPHVGMPFNQLGTLAGSKFYNVEATYYYLRCIQSDAPFEGAYGNLKRLFDKAAKMYHQVKKPEMKKLSPSRKRSKDVKRLLVSFMYLQSLLQPKNSLLETELTSLCQSVLEDFNLVLFYLPPPAHGGAQHSPSEEEEEQHQQHPDVSCPVLPDGLIFKMVVTCLMVVHSLKRGGSKQYSASIAFTLALFSHLVNHVNIRLQAELEEGGGQVPALHTDAADDADGRDLSAPPMDCSSEKPLQNGIVGEEEEKEDGDKKPSSEEDQSKKEEKQRQKKKYVRLSRLRRRRCARKDGQEDESDLSEGFESDEEEDNEEERQGRADSTGGISMGSPVNPSSVKKETKRDPLGEEVIWGSGSEEEEGGTAFDVETDSDMNSQESRSDLEDIEDTENSEAREHQEEEEDAEHAKEGGGGGDADGDLPPNSNGPSMPSDASISSNLQAMSSQLFQTKRCFRLAPTFSNMLLRPQASSSSGIPTPTDTSAPPSQETPPPSGDSPCDLNPGTANGTNDDDLDSDSEESQHSAPSVRSEKTLLEKLEILTNQGLIQVVKVFVDWLRTNTDIIVMCAQSSQSLWNRLSVLLNLLPDNSKILEADLGLNPQLTEMLNECEQPALVQTLLLPEDLTLRHLPALNAAHRRLDFAGRNLSLSPVHECVVRVCCIRSFGHFLTNLEGNVLHFNPEAGIFTSISQAEQDNLLQQAKAQFRMAEEEARRNRLMRDMAQLRLQLEVSQLEGSLQQPKAQSSMSPYLVPDTAALCQHLSLIRQLAGSGCFIIIIPRAVIDGLDALKKENAGARDGIRFLESEFRKGNRYIRCQKESGRSFERDKLKRQDLEAWHLYKTVDSCRQLTVSQSNGDEDTAGMVTILTGGEVEELCSRSAAMKAAVTERACISVYIRTVPFCCNYRVHRGAEESSNSDK
The following text describes a protein:
Function:
Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
Subcellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein.
Sequence:
MATLVANLARARVLLARNIAERGLPAARQAVPVRTKITNAAGALLPEPYNIRFGLAKVVAVMVPFIYVGATMSREGAAFLEENDIFVPDDDDDD
The following text describes a protein:
Function:
CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MYGYLRETDDSTAINFSAYGKFLPGENTGFQLLTIGAKFIRIFRVNPYVLKEPGEDNEEWQQKTKLECMFSCRLLNKCHSIAVARVPQLPDQDSILMTFDDAKLSIVSINEKERNMQTISLHAFENEYLRDGFINHFQPPLVRSDPSNRCAACLVYGKHIAILPFHENSKRIHSYVIPLKQIDPRLDNIADMVFLDGYYEPTILFLYEPIQTTPGRACVRYDTMCIMGVSVNIVDRQFAVVWQTANLPMDCSQLLPIPKPLGGALVFGSNTVVYLNQAVPPCGLVLNSCYDGFTKFPLKDLKHLKMTLDCSTSVYMEDGRIAVGSRDGDLFLLRLMTSSGGGTVKSLEFSKVYETSIAYSLTVCAPGHLFVGSRLGDSQLLEYTLLKTTRDCAVKRLKIDNKDPAAAEIELDEDDMELYGGAIEEQQNDDDEQIDESLQFRELDRLRNVGPVKSMCVGRPNYMSNDLVDAKRRDPVFDLVTASGHGKNGALCVHQRSLRPEIITSSLLEGAEQLWAVGRKENESHKYLIVSRVRSTLILELGEELVELEEQLFVTGEPTVAAGELSQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVIQASIVDPYVALLTQNGRLLLYELVMEPYVQLREVDISATSFATWHATAQNLTQLTSISIYADASEIMKFAAAEKSMGGGGGGDGEVSTAENAMMKKEQHEEAILLHGEDDDFLYGDEDETIMEQNFPVENGEATIKQSNTRKRKRLGHDAIQSSRGGEQSDAIDPTRTFSSISHWLIVSHENGRLSIHSLPEMEVVYQIGRFSNVPELLVDLTVEEEEKERKAKAQQAAKEASVPTDEAEQLNTEMKQLCERVLEAQIVGMGINQAHPILMAIVDEQVVLYEMFSSSNPIPGHLGISFRKLPHFICLRTSSHLNSDGKRAPFEMKINNGKRFSLIHPFERVSSVNNGVMIVGAVPTLLVYGAWGGMQTHQMTVDGPIKAFTPFNNENVLHGIVYMTQHKSELRIARMHPDFDYEMPYPVKKIEVGRTIHHVRYLMNSDVYAVVSSIPKPSNKIWVVMNDDKQEEIHEKDENFVLPAPPKYTLNLFSSQDWAAVPNTEISFEDMEAVTACEDVALKSESTISGLETLLAMGTVNNYGEEVLVRGRIILCEVIEVVPEPDQPTSNRKIKVLFDKEQKGPVTGLCAINGLLLCGMGQKVFIWQFKDNDLMGISFLDMHYYVYQLHSLRTIAIACDARESMSLIRFQEDNKAMSIASRDDRKCAQPPMASQLVVDGAHVGFLLSDETGNITMFNYAPEAPESNGGERLTVRAAINIGTNINAFVRLRGHTSLLQLNNEDEKEAIEQRMTTVFASLDGSFGFVRPLTEKSYRRLHFLQTFIGSVTPQIAGLHIKGSRSAKPSQPIVNGRNARNLIDGDVVEQYLHLSLYDKTDLARRLGVGRYHIIDDLMQLRRMAFYY
The following text describes a protein:
Function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis. May be involved in the synthesis of short and medium chain fatty acids. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain.
Sequence:
MFLIIVGITFLMSRSVLVVILGIAKHYTCLNLRRRLEVESVWEMAHSIFLGPSYIRPAIASARVLLPLPPPSAVAVRLTRTTRKVYHFRSRINMQSLRDSVLTRLRVTVCRRQFALMQDVYATSSVQRLLCTLAGSNHDQVMARVIGLVKKFDKIDAAKVTESADFSKDLSLDSLDRVELVMAFEQEFSIEIPDEEADKLKCCADVANYIQSAPKSEDS
The following text describes a protein:
Function:
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
Subcellular Localization:
Cytoplasm.
Sequence:
MGSSDTVEQPAEQQPAELLALEEQTFSVLVAPPAAKSGQCVRLESVGASDTVVSLRQLIAEFPALACYTSYHLEAKSSADGSWQPLNDFVELGEYESVADGVTLRMALDKFDARKVRGHVRRFRDVLNNPPIPQAATEPEAQPEGVADTSNEEPDDKALKEMSEKQLKRLREIHHKLEGVEVPVKPELAEFYAFPTPVAQEDAEPTPAKDQKKAKKGKKNQLKQKQNEANQHKEPEQKQQDAKLPTCVKSIVFSGYNPPPGPRKLAGDLLYLEVVVAGDNTRYHITAHVNGFFVNRSTATKFDPRPHKTAAAHAHLLVDVLSSVSPKFRESYAALLAKAASLAKEGPSSIEWMVAAGSSLGGKLPWNTPAATATEEHTYDLNRAEDELCASFGMDERGVLRDWNEEYQCCRELSTDSLKDEIVRARVMYKIVTEFVEAATQGSVAIVEGHIPPINPMDDKSAHVYVFNNIFFSMSIDGNSTKDAAGGEENAYSAANRDLQGVKAFNEADVRGLHTLATTVVDYLGVRVIAQSIIPGILMGDAASKLVYGSVDHGKTIAANNKMHKLMLEAGEKLHIAERSIKPLGKTEEDLAVEKEQEALGVAPGSGGEASTDVATICGAVEAKGIQGSDGRLYVLDLVRITPKDWTFYKSRDTALKKQEEKSIPSEEDGLCFTRNDEGYAALLRPELVQLYSLWKQNQARRVNREARIAAKEAKKAEEANENKENGAEADTEKKEDATSEKKETEEADEEEETAAVPPVLLNPNVFMDYAASTNAEQLEADETAAKDAAEYLQRIVVPAFVADVRRGASAPADGYSLTQLMHSCGINMRYLGRLALLAKKLEAIGGISKYFLEVLEVEMISRVAKHILADVLNSNDSIRAAPGSAIVKLLNGILGSTSAVADKKDVFETDDAAATTTASLDANTLWSRIDKEIKARFDYKLALWGPGRGEASADDATFPVGRAHRIVLLRRLCQRLGLRVVSRNYDFSSSCATPISLDDITGVVPVVKHSLPAHPFAQAKQLLERGRQHLGQGALSSAYEFLQEASSLLFQVCGAAHEDAALCSSSLATVLYHAGDVVGAIAQQQRALALYTQLQGIDYHDTAFAHANLSLFLHANAQTDLAVPHIRRAIYLLEFCCGPHFPEISSLYFKMGMMCQDVGQITLALMCHRESLRRGELDRNQAANVLHQMAMACGLAGGFREALTYEKKVYSLFKEAYGEEDPRVIDSAKFMAAFTEKAVEGAKGRREGDAAAAADAIANELLGELEFKTEADQQAGSPPAAKKKTRKTKSGSKKH
The following text describes a protein:
Function:
Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.
Subcellular Localization:
Nucleus.
Sequence:
MKVDKPGPRKKPLPPLPSSFYHLYTSKPASQLDASCETDKNGKVRALPHIEGQWPTHVYLEWKPDVAWRRLEMLNGAIAKVLETYQVVYHSLAKSDVGVRLPLHVSLSDTLMPTTESKQQVTDSICEAVTGWKGPIKINVSKTKLQVVLNRQKTRAFVVLALTDNEPIVRLIAAVNAAVEPHGLPALAAHPHVSIGWFLPRADPDPVSDAIVTSPETDRHLTALFGKVTFDCVKIKCGRLVQSVRCI
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
Subcellular Localization:
Chromosome, centromere, kinetochore. Nucleus.
Sequence:
METLSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYMRALQIVYGIRLEHFYMMPVNSEVMYPHLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRFLSGIINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEFKQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESLKTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQDLSDNREKLASILKESLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQEIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELKRKMFKMST
The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MNQNGDKNEGKLFQLPSLPPWKTPRFNKANFNNFTTPLRKRSTRVINDDSMPITGEVLEERTADDLYGINMDVDEVDYLNTLSHIEEEKQYDYSPFCERNTLRESRIDSFLKAERAAHCLVFHKVGHLDGIDSYRPDIDIMCGEEANKYDSANPEGNGSMLLESVPGCNKEDLERLSRREFVTNSKPNMRRLDDIINHETNALKSFWNDSGLVNSLQSHHLHEEYLLLQEELKNVYKIKCHDRVPIESLRDKCRRHYSNEDSSFL
The following text describes a protein:
Function:
Repressor of jasmonate responses.
Subcellular Localization:
Nucleus.
Domain:
The jas domain is required for interaction with COI1.
Sequence:
MSASSEIVDSGRFSGHKTTEKSNFSQTFNLLSQYLKENGTFGDLSLGMATGTMNLFPATNTSSHRQQDATAAAAASPVSTQVPKKQPESAQMTIFYAGQVIVLDDFPAEKAMEIMTLAGKGTTQKTQTFRPASDWIPKPTEPSNLVASNIEKESVQLQPVVSDLPIARKASLARFLEKRKERITARSPYQSDNHGSPSKQEEGKSWLGLAAESRGQFQAQSAS
The following text describes a protein:
Function:
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
Subcellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane.
Sequence:
MSSVSVHYSTHKINKVRFLNRNFHNDTSLFVTGTNHPVLSKNKISVWGLESRQNSDEIEELASVPIDGIVTELKVIEINNKPMIIGSTSKGSIFMYSIFNLPNKFEYIGYDGLLDKKYENYNNINNINDTYDTCNLLKERIWFNSSSNNNNVNSNNINNNNYNNNNNNYNNNNNNNNNNNNNNNNNNNNGSCINSFDISYDQHSLVTVGNDGVMNLLSIENLIPIYTNRYIDGLSVNVVKSITSNQIITSGELGRYIKFWDIRSNSSQPVKTIKTQCPRIFSLAIHKDEQHIIAAGSSDGQVNLFDIRNDYSIDQNKTHNSNVWELSFSKSNPNQLYSCSEDGFIYQYSYNKDNLGGGGMMTLPNQINNTFDIYSKEVSLLQLPTSIGSIDSFDINSNINRLICCSTSSQCLIVKSL
The following text describes a protein:
Function:
Catalyzes the transfer of the methyl group from monomethylamine to the corrinoid cofactor of MtmC (MtmC1 or MtmC2).
Sequence:
MTFRKYFDCYDFYDRAKVGEKCTLDDWDLMKIPMKAMELKQKYGLDFKGEFIPTDKDMMEKLFKAGFEMLLECGIYCTDTHRIVKYTEDEIWDAINNVQKEFVLGTGRDAVNVRKRSVGDKAKPIVQGGPTGSPISEDVFMPVHMSYALEKEVDTIVNGVMTTVRGKAPIPKSPYEVLAAKTETRLIKNACAMAGRPGMGVOGPETSLSAQGNISADCAGGMTCTDSHEVSQLCELKIDLDAISVIAHYTANSDIIMDEQMPIFGGYAGGIEETTIVDVATHINAVLMSSASWHLDGPVHIRWGSTNTRETLMIAGWACATISEFTDILSGNQYYPCAGPCTEMCLLEASAQSITDTASGREILSGVASAKGVVTDKTTGMEARMMGEVARATAGVEISEVNVILDKLVALYEKNYASAPAGKTFQECYDVKTVTPTDEYMQVYDGARKKLEDLGLVF
The following text describes a protein:
Function:
May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton. May act as Rab effector protein and play a role in vesicle trafficking. Required for perinuclear sorting and insulin-regulated recycling of SLC2A4/GLUT4 in adipocytes (By similarity).
Subcellular Localization:
Cytoplasm. Membrane. Endosome. Note=Mostly found in cytosol and plasma membrane.
Domain:
The CAAX motif is a signal for prenylation and required for endosomal colocalization with Rab8 and Rab10; The bivalent Mical/EHBP Rab binding (bMERB) domain, mediates binding to Rab8, Rab10, Rab10, Rab13 and Rab15 (in their GTP-bound forms).
Sequence:
MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKDPHAEEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAKKEEKCVLQ
The following text describes a protein:
Function:
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
Subcellular Localization:
Secreted. Bacterial flagellum.
Sequence:
MALRVNFNAEAATTHTALLRNEKAMNKSLLRISTGQRILSAADDAAGLFIADQLATVGAALDQGNRNIQTGISALQIAETNVGQIFDKLQTIYTKAQSAANDINDPNARAALQRDIANLVDAIQKLGTDTEYNGIKLLDGTFANKVIHYGARADQTITTSIGNVKATNIGAFVVQGSGQVTSSATSAYTSLIAGDWQYNSASDTVTVAGVNLKNYSALSSVTGAVDAKSIADAINNNATLQGVGISARAVNTSTATTEWSNIDNSSGTAAVTIKFYVGSSTASASAISITVAAGETLTLDELVSQINTQASTKSLNITATNSGNKLALTTEGETIGLEIASATGAVAVNMAQFLQGATGTVAVGNTGSAVKVGNLIVTGTDSYNYDFTGISTASAGLGVAATGSGNFYNLYSIDVTDNSGAELAIDIVNTAIKKVDKVRTQIGSVINNLQAIYDGQKTSYDNTKEAENVIRNTDFAAEMSTFTTMQIRMQAGVAMLAQANALPQLVLQLLR
The following text describes a protein:
Function:
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Miscellaneous:
MISCELLANEOUS: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Subcellular Localization:
Mitochondrion.
Sequence:
MLSIPEDKVEQYCDDLGGFLNSVESIQSVNTENVRPLHSILEDTQLTLHFEQTTVNQDHEHILDHSNNVQGGFFTVPKQISSHTNSQKSNKNNSIDDEF