lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
Subcellular Localization:
Nucleus.
Sequence:
MPGVVDTPGGPLWPGLGFTVAHQKVELEIDFATKSLKGKTEITIHPHYKELRIIRLNFRQGELKRLNVNGKAPTIKYADPYESLQLYGPHYHQRLSTKIDSLLTTTPEPDLLVTIPKSVRIEELDPFSQEAQDQMTLRASGAGEDTDGPLGSKLAETSLPRFSALTVYIEFTIENIRDGLQFVGVDSGDRRYPHAYTTNSLGYGAASPLFPCVDDPLSRCTWEISVKCPCSLGDVFDRKTRDPSGAHRSKQTPGGSRFISPDDETLDLSVVCSGDMTDEIVDPRDPSKKTVSFACMSPLSAKQIGFAVGPFEYINLSDFRESDQDEQLGQNAIPLHAFCLPGRGDEVRNTCFPMAKAIDFLSLTYGSYPFASYKICFVDDAPENTLPTACLSICSNHLLFPEDIIDPMYDSTRALVHALSCQWIGVNIVPKEPADTWVTVGVAWYITDTFLRKLCGNNEYRFRLKLMSDRVCDLDYERPSIYDMGNILNLDPSEIEFIALKAPLVLFILDRRLTKASGKATMSRIISRMFLNARMGDIPNGAITSSQFQKICERLGHAKLDTFFQQWVYGAGCPRFQATQRFNKKKLVVEMMIKQVQADQPSTRDLDKNTFMRDVKEEIRGVYAGNIQPVFSGSMTIRIHEADGTPYEHIVEIKEGVTKFDIPYNTKYKRLKRNKRQKERAAAVSGGDPNAETQEDVLLYCLGDVLQTEEEMQEWRLADWSKEDEDRMGQESYEWIRMDADFEWICKLSLVMPGYMYLSQLQQDRDVVAQLESLQYMAAQREHPLISTIFVRTLMDRRYFYGIREAAARALVKHAKEETNWLGLFHLERAFQELFCLPGSPMTRSNDFSDRAAYALQLAIPEAISKVRDNDGKTPLRVKRFLYDKLKFNDNSNNEYSDHFYVATLMQSLCHAMLGKVESRDVDIDDFDMERMLEIQAEEQLEKDAIAEFDRYRRMDEWSSSFQNVYSRAALRCQMQLMRAKILDVDIMQFLPYTRAGTYDLLRADAFECLVELDIFKSPELVKWFMFTMSSDSSLWLRRRLHDLFGKALAPVAFGREPENEPSATADSLIIEQESSTKVRQADLARKQTVTGAIEALKGEISGDQNFKECLWAACNSPGIGILELSVFTDLCKVLYDSVTSVMVKLKYPRYWQVKHLGKVIPFQSWISNLILIASGPHAFLTVQPNQDYPRTLKRFLHKWEAQTRRERDASTWAPYHIQAIEAGFKHPLSKSSSNLATHSEAAHPKPLRFAGTSATEDAGCSVDAVDTKWWRRRAQTETQIRAEAEISCLPAMVFYRNFFTSVLFTSHLFETWRGMVEQASRRMAGRPVSNDLYMLTFIIFYDGAACSLALGFIGFFV
The following text describes a protein:
Function:
Structural component of the gap junctions.
Subcellular Localization:
Cell junction, gap junction. Cell membrane; Multi-pass membrane protein.
Sequence:
MSLFGLLLCLSFGFVHALVNFTNSALYDINDFRGVKEVHIPKCDSGCLIFAATTGDEFEQFPDGLDPYANNLFVTNNDNGEQHSIARLAQQRDNFQRKIPLTIITHGNISVVNSNQEQLRKTVFTIVLYVVQKNRADQLSYEVYDAFYTRGTTFKPQSDIVTFLSAYNFRVQSPPSTQSNEATVRLIGFDNALDNNVDGCPYAYKTPNTPTFVGFSIMANAPIVSLVIGKKEALSLQTDYVFNSVRDLSIDGFFTSPGWNGCAKPNNGGFQSFRTPDDLMSDSYLLQNHINNFTVTMDILPNFDSKHQLNVTEGNDLRKIYVVSGTQQQQLVFPNTHYLINDFQNMRSDQGFIVRYTSTVNSRISTTTSYASTLNQSLGCLLPLALLLMVLSEITGTLNFLNPQPDDDISDRLHYYYTTTFLLLTAVLVSLKMFGGRPIECWLPAEYKSNWEDYTEMYCWARSTYFVPIEEELPDWVPFFFVLVAAMFYAPCLIWRLMYTTSGIRLKCIMGFANDKANVQPATRRSNIQGLSAHLFSIFKHRFRCNSQQSFCQRLLNLRFYEAFLTYLYIFIKCLFLANVLFQMYLINKFLQTEAYGIYGFGVIMDLLGGHAWKESANFPVVTYCDLQIRVLGNVQRHTIQCVLVINIFTEKIFIALWMWYTLLAVITFTSIMSWVFTSLPFGQRKKFIIRRLELADVDFRRHSYDAELDEFVRDYVKMDGIFVLRMILIHSGVLVCTEVVDYMWEQYLAQIGERGKFSEVHTLERAAAARFDMEKDNNSKNVALYRKTAMLVPLVSREDSREGHD
The following text describes a protein:
Function:
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
Sequence:
MRRTLLLAWPVARRRLLSNLPDSTVYWGPRPHPQESAAAARRVTLATLRGKHRRGEPISMVTAYDYSSAVHLDSAGVDVVLVGDSAAMTAHGHDNTLPISLDLMLQHCRAVVRGAARPLVVGDLPFGSYESSPAQAVESAVRLMKEGVVDAVKMEGGAASRVGAARAIVDAGIAVMGHVGLTPQTISVLGGFRAQGKTVDGALKVVEAALALQDAGCFAVVLECVPAPVAAAATAALQIPTIGVGAGPLCSGQALVYADLVGMFQSPEHSKVTPKFCKQFGDVGAAIGKALAEYKQQVEDRAFPDADHTPYKISSVDVDAFTDALRKIGFDGAAAAAAAAAAKTEEIVGDGKPQDGDVSNGILSHAGAAV
The following text describes a protein:
Function:
Transporter involved in a passive nitrate efflux.
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MASLVSGDKEAQISGDPGSKRGGWITFPFMLATLLGLSVTSFGWVMNLIVFLIEEFNIKSIAAAQISNVANGCLSMLPVVAAILADSFFGNIPVIAASSFISLLGIVLLTLIASLDYLRPRPCEAGSVLCTPPSKLHLGILYTALALVTTGAGGTRFTMASAGANQYEKPKEQGSFFNWYFLTLYAGAITGATAIVYIQDNASWKLGFGLCAAANLISFIVFVSGKRYYKHDKPMGSPFTSLIRVVVSATVKRKAVISCNEEDYHHYGLEKEVKTSAAMPSKSFRFLNRAALMTKDDLNQKEGSVNNIWRLCSVQEVEDFKAILRVFPLWLSIIFVSTPMVMQTSLIVLQALVTDRGLGPNFKVPAGSLQVIIIITACIVIIMNNWLVFPMYKKLTHKLLTPLQKVGIGQVLTILSMALSAVVEAKRLKTVENGHPMSVLWLFPPLVIVGIGEAFQFPANIELFYGEFPESLRNTATSLTSVVIGISFYLSTALIDLIQRTTAWLPNDINHGRVDNVYWLLVIGGILNFGYFLVCSWVYKYRNLKDNDQEQDPKDGTM
The following text describes a protein:
Function:
As a member of the SWAP1-SFPS-RRC1 splicing factor complex, modulates photomorphogenesis by regulating the gene expression and pre-messenger RNA (mRNA) alternative splicing of a large number of genes, including those involved in plant responses to light signaling, probably by helping in the 3' splice site determination. Associates with and regulates EARLY FLOWERING 3 (ELF3) mRNA processing, a key component of the circadian clock also involved in photomorphogenesis. Required for light-regulated (red, far-red and blue lights) photomorphogenesis in a PHYB- and PHYTOCHROME INTERACTING FACTORS- (PIFs) dependent manner. Promotes flowering under both short (SD) and long days (LD). Controls abscisic acid (ABA) sensitivity during seed development, stomatal responsiveness and germination by monitoring ABI3 splicing, upstream of the splicing factor SUPPRESSOR OF ABI3-ABI5. Seems to be involved in the resistance to UV light and chemical DNA-damaging agents.
Subcellular Localization:
Nucleus. Nucleus speckle. Note=Observed in subnuclear light-induced structures called photobodies in response to light. Colocalizes in nuclear speckles with U2 small nuclear ribonucleoprotein-associated factors including U2AF65B, U2A' and U2AF35A and with SF1.
Sequence:
MLGGLYGDLPPPTDDEKPSGNSSSVWSSSTKMAPPTLRKPPAFAPPQTILRPLNKPKPIVSAPYKPPPPSNSSQSVLIPANESAPSHQPALVGVTSSVIEEYDPARPNDYEEYKREKKRKATEAEMKREMDKRRQEDEERDKREREEREKERERDNSDPSRLNISGEEAWKRRAAMSGGGSGGKGRSSSPPGNVDGFSIGKSETSGLGVGAGGQMTAAQRMMAKMGWKQGQGLGKSEQGITTPLMAKKTDRRAGVIVNASENKSSSAEKKVVKSVNINGEPTRVLLLRNMVGPGQVDDELEDEVGGECGKYGTVTRVLIFEITEPNFPVHEAVRIFVQFSRPEETTKALVDLDGRYFGGRTVRATFYDEEKFSKNELAPVPGEIPGY
The following text describes a protein:
Function:
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Subcellular Localization:
Cytoplasm, cytoskeleton, actin patch.
Sequence:
MAAPEVHHLFHHPIADHSFSADRQTLAVARENNVDLYARSGSGFKLQDELTGHDKTVTGVDIAPNSGKIVTCSQDRNAYVWEPSPQGWKPTLVLLRINRAATCVRWAPSETKFAVGSGARLIPVCYFEEEDNWWVSKHIKKPIRSTVTCVAWHPNSVLLAAGSTDGHARVLSSFVKGVDERPEASAWGERLPFNTVCGEFLNNTAGWVHSVAFSPSGNALAFASHDSTLTVVYPGGPDQPPNAVLSVSTQVLPFMSLVWSTEDEIIAAGYNCEAYRLQGNEQGWQLAGSLESKGRPGLTEAREESALNMFRQMDLKGKSGGTDDTKLKTVHQNTINTIRSFQEDGGNVTKISSTGVDGRVVIWSFFPNNPTLAPFSCPILTRRYLIYRSLRSSLPNLYSSRMDEMLEEM
The following text describes a protein:
Function:
Neuropeptide that triggers the performance of ecdysis behaviors at the end of a molt. It triggers adult behavior patterns: larval, pupal and adult ecdysis, and plasticization during the molt.
Subcellular Localization:
Secreted.
Sequence:
MNCKPLILCTFVAVAMCLVHFGNALPAISHYTHKRFDSMGGIDFVQVCLNNCVQCKTMLGDYFQGQTCALSCLKFKGKAIPDCEDIASIAPFLNALE
The following text describes a protein:
Function:
Possible role as a cell-adhesion or receptor molecule of erythroid cells.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Sequence:
MERPSPCGSWLVGCLFTIAVFQPPVQVLGDAGKVYIAPLRDTANLPCPLFLWPNMVLSEMRWYRPGHLPRTQAVHVFRDGQDRDEDLMPEYKGRTALVRDAHKESYILQISNVRLEDRGLYQCQVWVGNSSREDNVTLQVAVLGSDPYIHVKGYDAGWIELLCQSVGWFPKPWTEWRDTTGRALLSLSEVHSLDENGLFRTAVSSRIRDNALGNVSCTIHNEALGQEKTTAMIIGAPERGSLSSPAVALSVVLPVLGLLILLGIWLICKQKKSKEKLLYEQAMEVENLLEDHAKEKGRLHKALKKLRSELKLKRAAANAGWRRARLHFVAVTLDPDTAHPKLILSEDRRCVRLGDRKRPVPDNPERFDFVVSVLGSEYFTTGCHYWEVYVGEKTKWILGVCSESVSRKGKVTASPANGHWLVRQSRGNEYEALTSPQTSFRLKESPKCVGIFLDYEAGIISFYNVTDKSHIFTFTHSFSSPLRPFFEPCLHDEGKNTAPLIICTELQKSEESIVPKQEGKDRANGDVSLKMNPSLLSPQGSELFLLNDTWPSNLGPALKGLKVPSL
The following text describes a protein:
Function:
Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MTNNSVDLSTGGMATDWDGGSFASTTQQPFDTVPRSQTVNIYLLICIYVIIFLLAVIGNILVIVTLVQNKRMRTVTNIFLLSLSVSDLLFAILCMPFTLVGNILQRFIFGEGICKIISYFQGASVAVSVWTMCAISLERYHAICNPLASRAWQTKSRACKITVAVWLMSFLVLLPFAIYTEHEKIGDTEYYKCREKFPTQFHKLYITSIFMALMFIPLFMMCIAYALIIRELWRGMHYERQNTKREKEQNGTPLNDLSKKKKGRKALMDDSSATESFLRKSRGGTGASSKKGESAHATPRSTSSNTAKKRVVKMLLVLVILFFVCWTPTWSMNIWATYDPKGAYSSVSTLQVTLIRLMMYTSACVNPIIYCFMNKKFRQGLIDAFGCCCCCFVGKKADTASLPSQTSVRRNHPVQRPHSTNYTNRWPGQSALRLIVHSQQFNKITTPGLVRAV
The following text describes a protein:
Function:
Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed.
Subcellular Localization:
Nucleus.
Sequence:
MAGAAPRVRYLAGFCCPLGGLAAGKPRVLCHEAEVFLSTGSELVYVYDQEGGLLTAAFRFPDQVWHLELLAPRRLLYALCARRGLYCLSLDHPGRSRSTSQDDRDSEDGDQPSPVIPVDPDACILPDAALCAFTLLDSVLVTLVQGPARWKMQLFEQPCPGEDPRPGGQIGEVELSSYTPPAGVPGKPAAPHFLPVLCSVSPSGSRVPHDLLGGSGGFTLEDALFGLLFGADATLLQSPVVLCGLPDGQLCCVILKALVTSRSAPGDPNALVKILHHLEEPVIFIGALKTEPQAAEAAENFLPDEDVHCDCLVAFGHHGRMLAIKASWDESGKLVPELREYCLPGPVLCAACGGGGRVYHSTPSDLCVVDLSRGSTPLGPEQPEEGPGGLPPMLCPASLNICSVVSLSASPRTHEGGTKLLALSAKGRLMTCSLDLDSEMPGPARMTTESAGQKIKELLSGIGNISERVSFLKKAVDQRNKALTSLNEAMNVSCALLSSGTGPRPISCTTSTTWSRLQTQDVLMATCVLENSSSFSLDQGWTLCIQVLTSSCALDLDSACSAITYTIPVDQLGPGARREVTLPLGPGENGGLDLPVTVSCTLFYSLREVVGGALAPSDSEDPFLDECPSDVLPEQEGVCLPLSRHTVDMLQCLRFPGLAPPHTRAPSPLGPTRDPVATFLETCREPGSQPAGPASLRAEYLPPSVASIKVSAELLRAALKDGHSGVPLCCATLQWLLAENAAVDVVRARALSSIQGVAPDGANVHLIVREVAMTDLCPAGPIQAVEIQVESSSLADICRAHHAVVGRMQTMVTEQATQGSSAPDLRVQYLRQIHANHETLLREVQTLRDRLCTEDEASSCATAQRLLQVYRQLRHPSLILL
The following text describes a protein:
Function:
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
Subcellular Localization:
Cell inner membrane; Multi-pass membrane protein.
Sequence:
MADFKPDFAWLLKRPLCFLAFGFGSGLAPFAPGTFGTLAALPLAFVLILLGIDGLLLAFLCIVLFMWGIRICAYAERETGVSDHGGIVWDEIVAMLFVLAFVPFRWTWWLAAFVLFRLFDALKPSPVGWFDKNLHGGLGIMADDMAAAVMTLIVLRIAMLF
The following text describes a protein:
Function:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Cleaves BIRC6 following inhibition of BIRC6-caspase binding by DIABLO/SMAC.
Sequence:
MEEKHKRILRRNRVHLVKELDLSDLCDVLLRKDVFTQSMINDIKNCETKRDQARKLVKDLETRGNEAFSAFLEGLRVTGQQNLLELLQKSAPRVHFQPGKSTEAGYLLIQPHPVYIEDAVPKKPRTQPSPPPDEVFKGPEVRPRRDSIQYYKMDARPCGLCLIINNVEFEPKTELSIRKGSNVDCDKLEKRFKSLNFVVEVRTNLKQRQIKSELSALSRKDHSIYDCCVVVILSHGTEVRHNKIRSAGSWIEIDQVSHNRFPGAVYGVDGNHVSVQEITNYLNGQNCPSLQSKPKIFFIQACGGGEKDIGFEVSPDEAKPSIGGDGDQTDAIPFSSSSESLSTSDETDAIPTLPTPSDILVSYSTFPGYVSWRATVSGSWYVEVLDNILEEHAATLDLTTMLTLVNDKVSQNSAKGLYKQMPGSFNFLRKHVYFQTSE
The following text describes a protein:
Function:
Pyridoxal phosphate-dependent decarboxylase that catalyzes 1 step in the biosynthesis of the side chain of the aminoglycoside antibiotics in the biosynthetic pathway of butirosin. Able to decarboxylate L-ornithine, L-arginine, L-lysine, but not L-glutamate or any D-amino acids. Has low activity with substrates not bound to an acyl-carrier protein.
Sequence:
MNLDQAEITALTKRFETPFYLYDGDFIEAHYRQLRSRTNPAIQFYLSLKANNNIHLAKLFRQWGLGVEVASAGELALARHAGFSAENIIFSGPGKKRSELEIAVQSGIYCIIAESVEELFYIEELAEKENKTARVAIRINPDKSFGSTAIKMGGVPRQFGMDESMLDAVMDAVRSLQFTKFIGIHVYTGTQNLNTDSIIESMKYTVDLGRNIYERYGIVCECINLGGGFGVPYFSHEKALDIGKITRTVSDYVQEARDTRFPQTTFIIESGRYLLAQAAVYVTEVLYRKASKGEVFVIVDGGMHHHAASTFRGRSMRSNYPMEYIPVREDSGRRELEKVTIAGPLCTPEDCLGKDVHVPALYPGDLVCVLNSGAYGLSFSPVHFLGHPTPIEILKRNGSYELIRRKGTADDIVATQLQTESNLLFVDK
The following text describes a protein:
Function:
Involved in cell surface assembly and regulation of the gene related to flocculation (asexual cell aggregation). Mutations in SFL1 causes constitutive cell aggregation.
Miscellaneous:
MISCELLANEOUS: Present with 1040 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSEEETVSAPAPASTPAPAGTDVGSGGAAAGIANAGAEGGDGAEDVKKHGSKMLVGPRPPQNAIFIHKLYQILEDESLHDLIWWTPSGLSFMIKPVERFSKALATYFKHTNITSFVRQLNIYGFHKVSHDHSSNDANSGDDANTNDDSNTHDDNSGNKNSSGDENTGGGVQEKEKSNPTKIWEFKHSSGIFKKGDIEGLKHIKRRASSRNNSSINSRKNSSNQNYDIDSGARVRPSSIQDPSTSSNSFGNFVPQIPGANNSIPEYFNNSHVTYENANHAPLESNNPEMQEQNRPPNFQDETLKHLKEINFDMVKIIESMQHFISLQHSFCSQSFTFKNVSKKKSENIVKDHQKQLQAFESDMLTFKQHVMSRAHRTIDSLCAVNAAATAASVAPAPAPTSTSAYAPKSQYEMMVPPGNQYVPQKSSSTTNIPSRFNTASVPPSQLFVQYQPQSQQHVTYAKQPAHVPNFINQPIPIQQLPPQYADTFSTPQMMHNPFASKNNNKPGNTKRTNSVLMDPLTPAASVGVQGPLNYPIMNINPSVRDYNKPVPQNMAPSPIYPINEPTTRLYSQPKMRSLGSTSSLPNDRRNSPLKLTPRSSLNEDSLYPKPRNSLKSSISGTSLSSSFTLVANNPAPIRYSQQGLLRSLNKAANCAPDSVTPLDSSVLTGPPPKNMDNLPAVSSNLINSPMNVEHSSSLSQAEPAPQIELPQPSLPTTSTTKNTGEADNSKRKGSGVYSLLNQEDSSTSSADPKTEDKAAPALKKVKM
The following text describes a protein:
Function:
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
Sequence:
MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRRELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSKNAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAESKEDAA
The following text describes a protein:
Function:
Histone-binding component of the NuA3a histone acetyltransferase complex. Targets the NuA3a HAT complex via histone H3K4me3 to facilitate transcription initiation at promoter regions. SAS3 then acetylates H3K14, leading to transcription initiation at a subset of genes. YNG1 is required for the HAT activity of NuA3 but not for its integrity. Mediates the interaction of SAS3 with nucleosomes.
Miscellaneous:
MISCELLANEOUS: Present with 861 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Domain:
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence:
MEHLANENSDSDIRYSFLSTLDHLPCELIRSLRLMQTIDLFKNEEDEPGMERACRDLLLVATYINDLVDDQIHFLKQHKKELEIQKSVTKNFNSSLENIKSKLTLEEPGAYKEPKLLLKINLKKAKSRERKESITSPTIGINQGDVTEGNNNQEEVYCFCRNVSYGPMVACDNPACPFEWFHYGCVGLKQAPKGKWYCSKDCKEIANQRSKSKRQKRRK
The following text describes a protein:
Function:
Acts as a receptor for PEP defense peptides. Unlike typical immune receptors, senses an endogenous elicitor that potentiates pathogen-associated molecular pattern (PAMP)-inducible plant responses. Involved in PAMP-triggered immunity (PTI) signaling. Interacts with and phosphorylates the kinase BIK1, a central rate-limiting kinase in PTI signaling.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein.
Sequence:
MKNLGGLFKILLLFFCLFLSTHIISVSCLNSDGLTLLSLLKHLDRVPPQVTSTWKINASEATPCNWFGITCDDSKNVASLNFTRSRVSGQLGPEIGELKSLQILDLSTNNFSGTIPSTLGNCTKLATLDLSENGFSDKIPDTLDSLKRLEVLYLYINFLTGELPESLFRIPKLQVLYLDYNNLTGPIPQSIGDAKELVELSMYANQFSGNIPESIGNSSSLQILYLHRNKLVGSLPESLNLLGNLTTLFVGNNSLQGPVRFGSPNCKNLLTLDLSYNEFEGGVPPALGNCSSLDALVIVSGNLSGTIPSSLGMLKNLTILNLSENRLSGSIPAELGNCSSLNLLKLNDNQLVGGIPSALGKLRKLESLELFENRFSGEIPIEIWKSQSLTQLLVYQNNLTGELPVEMTEMKKLKIATLFNNSFYGAIPPGLGVNSSLEEVDFIGNKLTGEIPPNLCHGRKLRILNLGSNLLHGTIPASIGHCKTIRRFILRENNLSGLLPEFSQDHSLSFLDFNSNNFEGPIPGSLGSCKNLSSINLSRNRFTGQIPPQLGNLQNLGYMNLSRNLLEGSLPAQLSNCVSLERFDVGFNSLNGSVPSNFSNWKGLTTLVLSENRFSGGIPQFLPELKKLSTLQIARNAFGGEIPSSIGLIEDLIYDLDLSGNGLTGEIPAKLGDLIKLTRLNISNNNLTGSLSVLKGLTSLLHVDVSNNQFTGPIPDNLEGQLLSEPSSFSGNPNLCIPHSFSASNNSRSALKYCKDQSKSRKSGLSTWQIVLIAVLSSLLVLVVVLALVFICLRRRKGRPEKDAYVFTQEEGPSLLLNKVLAATDNLNEKYTIGRGAHGIVYRASLGSGKVYAVKRLVFASHIRANQSMMREIDTIGKVRHRNLIKLEGFWLRKDDGLMLYRYMPKGSLYDVLHGVSPKENVLDWSARYNVALGVAHGLAYLHYDCHPPIVHRDIKPENILMDSDLEPHIGDFGLARLLDDSTVSTATVTGTTGYIAPENAFKTVRGRESDVYSYGVVLLELVTRKRAVDKSFPESTDIVSWVRSALSSSNNNVEDMVTTIVDPILVDELLDSSLREQVMQVTELALSCTQQDPAMRPTMRDAVKLLEDVKHLARSCSSDSVR
The following text describes a protein:
Function:
Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.
Subcellular Localization:
Nucleus. Cytoplasm.
Sequence:
MKLEASVEDTSGWTEEDFALNCTYIVQDQSSDPRFSLPRAMTSIPRNLSFQYNRDQQVTGVFSKEYIPQGTRFGPLQGVVYTKENVPLHTNRKYFWRIYSGGQLQHFIDGYDVRLSNWMRYVNPARSLAEQNLVACQNGPDIFFYTLRPLEPKQELLVWYSPEFSQRLCGQQETTDSTSTKYTSDMEYQKPPLPQYTYYPKHPSNPQNHPCDTNKDDEEPEEKIDIERDTPPDTPDEQIMDFSKKIHKSEPMHEKTNIYPSLSPPQDVPLHLHSLYGHREGLISSYPSIRSPYPLLPQYNPHYQHMLIPPYSPPFTSMLPTKPAHRYGFMNPDGLSYPSIPQSGLLPVSLPYPNTLHGGLNERGHNTPPRGAPATPELSPQTSPCQTHYSECEEAINLSLTTPKSTPPPSASPAMIPGYKSLPYPLKKQNGKIKYECNVCMKTFGQLSNLKVHLRVHSGERPFQCNLCKKSFTQLAHLQKHHLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKLCGVKFTQYIHLKLHRRLHSSRERLHSCAACSRSFIHRFSLRLHQRCGCCPAGRPQAPETLRRAAELLERFDASAEAEALPESAAEPQVDAALEEWLARSLQSGEEDGLLRACTGVPQQQDRATVVHFSHRSSIKTEEE
The following text describes a protein:
Function:
Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.
Subcellular Localization:
Nucleus.
Sequence:
MYNDDEEDVPTGPPPAKQGKHYLRQKLIKSSAPPPVIDLSARNKPMTTAATPKTFQPIRANPVAENISFLPKAATDESVMIFGEEHIKCEYFPMTPNNFEILAKELNDRKQREKNAREIAKRLQREHEEEDKKRSMGAAIAPPTMLMEPEPEVVKEKDDIPEDKPQSSFMPPPSFLPAFGKSTSRGLGIAANIMKKHGYREGQGLGKSEQGMSTALQVERVGARTGNIVGESPRVPSFAANSTEAVNNATKILQLWNLTDVGEVSGEEGKKEFASEIKEEMEKCGQVVEVIVHVSENEEDESRRVRVFVEFPTNAQAIKAFVMMNGRFFGGRSVGAGFQNVDDYNSRSF
The following text describes a protein:
Function:
Mitochondrial S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine in tRNAs and 12S rRNA. Catalyzes the methylation of uridine at position 54 (m5U54) in all tRNAs. Specifically methylates the uridine in position 429 of 12S rRNA (m5U429). Does not affect RNA stability or mitochondrial translation.
Subcellular Localization:
Mitochondrion; [Isoform 1]: Mitochondrion matrix.
Sequence:
MAGLKRRVPLHSLRYFISMVGLFSKPGLLPWYARNPPGWSQLFLGTVCKGDFTRVIATKCQKGQKSQKKPSHLGPLDGSWQERLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQMLNGVSVTTAVPKSERLSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFVLQQAVPVDLFPHTPHCELVLLFTR
The following text describes a protein:
Function:
Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Preferentially mediates ATP-dependent polyglutamate long side-chain elongation over the initiation step of the polyglutamylation reaction. Preferentially modifies the alpha-tubulin tail over a beta-tail. Required for CCSAP localization to both spindle and cilia microtubules. Promotes tubulin polyglutamylation which stimulates spastin/SPAST-mediated microtubule severing, thereby regulating microtubule functions.
Subcellular Localization:
Cytoplasm, cytoskeleton, cilium basal body.
Sequence:
MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLEAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVAGWGGGAAAAAVALALAPALSAMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVDAGAAGEPECKAGEEQPKALAPAPAQPSAAEEGDTQVLQRPPPTLPPSKPKPVQGLRPHGKPRGKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQLKWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPVLLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALDGELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQRDSGMCLQAFVEAFFFLAQRKFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGIPSGGRPPHRGPPQEPSPSAQPAGDNPPPRTSCANKLSHPRHTLS
The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MGGPELGYSCAHAQTLHPVWWSGLLGVWSSGPSTERVVMSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAGSLFDFPWRRALEMAACWTHGCSSDLRLLPPLIWCAGGEPREVPWLPCQNNFVLSIC