lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Negative regulator of the paaZ and paaABCDEFGHIJK catabolic operons. Binds the consensus sequence 5'-WWTRTGATTCGYGWT-3'. Binding of PaaX is specifically inhibited by phenylacetyl-coenzyme A (PA-CoA).
Sequence:
MSKLDTFIQHAVNAVPVSGTSLISSLYGDSLSHRGGEIWLGSLAALLEGLGFGERFVRTALFRLNKEGWLDVSRIGRRSFYSLSDKGLRLTRRAESKIYRAEQPAWDGKWLLLLSEGLDKSTLADVKKQLIWQGFGALAPSLMASPSQKLADVQTLLHEAGVADNVICFEAQIPLALSRAALRARVEECWHLTEQNAMYETFIQSFRPLVPLLKEAADELTPERAFHIQLLLIHFYRRVVLKDPLLPEELLPAHWAGHTARQLCINIYQRVAPAALAFVSEKGETSVGELPAPGSLYFQRFGGLNIEQEALCQFIR
The following text describes a protein:
Function:
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. Catalyzes the conversion of phosphatatidylethanolamine and does not act on phosphatidylcholine. Can utilize both phosphatidylethanolamine (PE) plasmalogen and diacyl PE as substrate and the latter is six times better utilized, indicating the importance of an ester linkage at the sn-1 position (By similarity). Although it shows no sn-1 fatty acyl preference, exhibits significant preference towards docosahexaenoic acid (22:6n-3) compared with 18:1 or 20:4 at the sn-2 position (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Highly enriched in the mitochondria-associated membrane (MAM).
Sequence:
MRRGERRDAGGPRPESPVPAGRASLEEPPDGPSAGQATGPGEGRRSTESEVYDDGTNTFFWRAHTLTVLFILTCTLGYVTLLEETPQDTAYNTKRGIVASILVFLCFGVTQAKDGPFSRPHPAYWRFWLCVSVVYELFLIFILFQTVQDGRQFLKYVDPKLGVPLPERDYGGNCLIYDPDNETDPFHNIWDKLDGFVPAHFLGWYLKTLMIRDWWMCMIISVMFEFLEYSLEHQLPNFSECWWDHWIMDVLVCNGLGIYCGMKTLEWLSLKTYKWQGLWNIPTYKGKMKRIAFQFTPYSWVRFEWKPASSLRRWLAVCGIILVFLLAELNTFYLKFVLWMPPEHYLVLLRLVFFVNVGGVAMREIYDFMDDPKPHKKLGPQAWLVAAITATELLIVVKYDPHTLTLSLPFYISQCWTLGSVLALTWTVWRFFLRDITLRYKETRWQKWQNKDDQGSTVGNGDQHPLGLDEDLLGPGVAEGEGAPTPN
The following text describes a protein:
Function:
Keratin-binding protein required for epithelial cell polarization. Required for ciliogenesis (By similarity).
Subcellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell junction. Note=Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to the apical junction complex (AJC) in epithelial cells (By similarity).
Sequence:
MATKSKSSVRGSIDDVLDDLLGYDDEGPAKSSQPAGVSSGRARGSSLQASKKSFLEDDFFSKLPAEDMEAAEGSSISDADPQAVLQTLKEMDDMEADLLGMSKPSSGLGKAATKGPGKFSTSEGAVKTSGKMPAPEKGESAPEMDKKPLSSPPTSRQYRKFNFEDVDDPLAGLLSEEEQDAPRKPSPKGSERRPERKTELGKEKDPLPPQTPLHTTAPARRREELTFEDDDDDMMDVLGFGDGQKGDQKHGKKAEEEEVRPARSKLDELLGRGSVAKILERPGAGEHREFKLDKKYQKQPEKEEGWDEEDFVFGAYQPTVATTPEGRPSRRQSVSRFSAENSSEPKPDPHSKPPPAASQSPARGSRAGGDWLGLKDEDFLDSEPPSPAKTSPVVSSQQLLAKEQATSKPNQLEEDNWLSAALSRKKAQAQVKAQERGAVPLETTGKGLDPSPAVSQPATSTGAAAQAAALQDKAASADSSGHPVPWLSTVTQTSAHPPEPAKRDPLRDVSPSDPAASSPAEQGMQGPAPLAQVTMPSTPLQAASQLQAESPPLGSVHERRPGAPTGQSYEDATGCRAALLSAQARVAELESQVRMLELERTQHKLLLESLQQRHQEDLDLLESAHRSRVKVVEETYGQREERLRREKEQLEAQLLSQSQDAERARADLVAQHKQRVATLEQQSAQELERLRELQRSSVQEMLKDHEEQLQRLKRLKDQEIDAVTSATSHTRSLNGVIEQMERFSSDLHSLSHKVEATHHTTSQELAMGARQRDEQLKVLQDRLSQQQRDMEEERSRLQEVIAKMEARLSEQTRLLEQERWRVTAVQSKVESLQRSLEEQRRLMTQQLSMERAELERAKSALLEEQKSVMQKCSEERRKLAVEWAEFHTQQQLSKERMERDIDRALQLDSQREGTIMSLAKEQAELKVRSRELKVKEEQLARDRLLLDEAWHELRLEKEKVKGATLRIRQQEEEIKNMSKLSAQKYEEGERALQDACRIESEHQARLQVMQQHLEQLKQQEQHLQQERLSMAHQRRQLEQLHKKLPNNPTLLLTTDQDLSASTKGLSSTLSFPPPIRTLPGHRSVGTTASMELYAKLLVLKHRAQQDRNFLEDEQLFLETLKKASYNTSPLSV
The following text describes a protein:
Function:
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
Sequence:
MPNHSVVSTETLSEHQVFVMSDASCCSTMSTKPQDRSDIGLFVVKNTIKAIEPSHKGTTSVTVNNMPVLRSDGQHSANPKQKKNQPTLLTVYGFATNDRKFNYLLKLRQASNGGVVEPVLVSERLSLPVDQCLTVHDQVKKLKVSVLGLLERYERVIYTGKEKMGKHFDYTVFVTDQNSRLRELFWLDFTRERVLTSHTIESVFLEYDRCQEEFTRLNTKYTNLLAEYNKVDAEIKAFEKMNDVSLLSCSLAKYVNVQNLDDFFTTDYLTCCLIVVPKTGVNEFLAEYAALGCEDADGAKKKGRPDQPTVTPTLPLDGDSAVLGVVPGSARRLKDDSTHALFSVILFKKDQQRCLDYFREKKWIVREYIPEEADAGSEGRLATLTHVKADREKAFQQHIESTLAACLALAIDTSILELYIEAQLRFGADFQMLMFMSSGVTRKGLKQIVNYSFNELLNGCDQRVYDVDVEAENPYLPFVLCSTKLADEAAIKAK
The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus.
Sequence:
MDFDEHDDGDGDEEMAPMPVSSSFEAPPPPQLLHPGLAHGVPVPKPGDSGGGRFRTPSVRYRECLKNHAVGIGGHAVDGCGEFMAAGEDGSIDALSCAACGCHRNFHRKESEESPAAAAVAAAAAGAITPYGAMPPLPGHHGQFSPYYRTPAGYLHHPQQHHHHHQMAAAMAAGHAQRPLALPSTSHSGGRDEAGAADVDMSAMMLSPVVMGSMSMAGLSFGSGGSAGGPYGSGGSAGKKRFRTKFSQEQKERMQAFADRLGWRIQKHDEAAVQQFCEEVGVKRHVLKVWMHNNKHTLGKKPLP
The following text describes a protein:
Function:
Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.
Subcellular Localization:
Mitochondrion.
Sequence:
MAHTLEPYKGCDILDINPGVGLWSQKLHEFLKPRNHILLEPSPDLFRPFLDPLLNAPDSKYKLVNKDPLKVESYRELVDEGAFPQQTRIDPQDPKGQDLNQTLLVTGSLAWDPFLPGLSFDSMAKQLYHHFTPAAWSNDLFHAFGPVRTLFWVQTEDFNHVVAKSPTYMLKSNRLLEMTQNLNLVVTSERESRPAGKGAIGREPQYEIESTIRAIRSAKKAGFDIPEHRRDVTHKYAELIEEASGGSGIINSETMMELMYAQYRAGNRPTQFLPQGILDCFEVEKQLQEEHPDLKLSPIFPLSKKTAATVTNKAHPASDKVREYTKTRALVAHRLRQRIKFEEIVIIGEEIYKLECKALKMKEGPGKAKTLKQIEQLEEQWDQRLAQLSRNLEHAPVAELDDRINLRYPPHPRIQWDQRLFDPLMSREDEVWPRNRVSLISATPIPRPASDDPEWHEQVIDFVFGLYANSNRSVIEALDSMQHGLSDIIKDCPSLTDPDKGGRLQLKHLRVKLLTMEMIYEMAKAYKEWPFKAPGSDRSLYFRHKN
The following text describes a protein:
Function:
CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Sequence:
MNPPYKLEPYEFVGLLGGGRFGTVQRMRDKRSGREVAIKFLVGGTKIDERVEREILVHRRLRHPCIPRLLEVRLTLYHLAIVMEFVEGTTLLQNLSERPHHRFAERQARFIFHQLVAIVNYLHSQGICHRDLSGNNILLKWVKVSEASKPYPVVYVCDFGMAKMEGVHSTPNSYIGTAEFVAPELLDVTAMTEGKEYDGQRADVWSMAVILLVMLTGISPFADPEAPHDQIRLFNRIRQGVYVTPQGVSPECLHFLACTLRTKPLERPSIDQLREHPWLQKDKDVAAAGYHMDDNDRYPIMAFQSEDEMRRIVHAARVINLPATSVR
The following text describes a protein:
Function:
Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes.
Subcellular Localization:
Virion tegument. Host cytoplasm. Host Golgi apparatus.
Sequence:
MQLAQRLCELLMCRRKAAPVADYVLLQPSEDVELRELQAFLDENFKQLEITPADLRTFSRDTDVVNHLLKLLPLYRQCQSKCAFLKGYLSEGCLPHTRPAAEVECKKSQRILEALDILILKLVVGEFAMSEADSLEMLLDKFSTDQASLVEVQRVMGLVDMDCEKSAYMLEAGAAATVAPPTPPAVVQGESGVREDGETVAAVSAFACSSVSDSLIPEETGVTRPMMSLAHINTVSCPTVMRFDQRLLEEGDEEDEVTVMSPSPEPVQQQPPVEPVQQQPQGRGSHRRRYKESAPQETLPTNHEREILDLMRHSPDVPREAVMSPTMVTIPPPQIPFVGSARELRGVKKKKPTAAALLSSA
The following text describes a protein:
Function:
Involved in the RNA silencing pathway. Cleaves double-stranded RNA to produce microRNAs (miRNAs) of 21-24 nucleotides which target the selective destruction of complementary RNAs. Regulates by this way the development of the plant. May not be involved in small interfering RNAs (siRNAs) production.
Subcellular Localization:
Nucleus.
Sequence:
MAGGGGVGGGAGEHAAAAYWYDACEDGASLLCGIDFAASADFDPGLIPAMDTGADDGFVAEIDRILESINAESSPAPPPPPPPPLPEPVPVAPPELPIQEKQLQVASAPVANNAVAVVGVVQRSKGVVARKEPRRESHGCAANGGGGGEWRDGKRPRLASGGVGGPRQEWRRRPMLPPPPSRGWDDRRGRRDFDRVRKHEHHRREARGFWERDRGGKMVFRSGTWEQESDREAKRARTQDGGSMEKKAEADRMGAAQREKPVAEERARQYQLEVLEQAKSRNTIAFLETGAGKTLIAVLLIKSVCDKMLKENKKMLAVFLVPKVPLVYQVLVMTAQILLNILRHSIIKMDAIHLLILDECHHAVKKHPYSLVMSEFYHTTPKEKRPAVFGMTASPVNLKGVTSQEDCAIKIRNLESKLDSVVCTIKDRKELEKHVPMPLEVVVQYDKAATLWSLHEQIKQMESTVEEAALSSSKRTKWQFMGARDAGSRDELRLVYGVSERTESDGAANLIQKLRAINYALGELGQWCAYKVAQSFLTALQNDERANYQVDVKFQESYLKKVVDLLHCQLTEGAAMKSETSDVEMQNTEKHNTNDLEEGELPDSHGEHVDEVIGAAVADGKVTPRVQALIKILLKYQHTEDFRAIIFVERVVTALVLPKVLAELPSLSFIRCASLIGHNNNQEMRACQMQDTISKFRDGRVTLLVATSVAEEGLDIRQCNVVIRFDLAKTVLAYIQSRGRARKPGSDYILMLERGNISHETFLRNARNSEETLRKEAMERTDLSHLDGTSVLSPVDTSPGSMYQVESTGAVVSLNSAVGLIHFYCSQLPSDRYSILHPEFIMQKYEKPGGSVEYSCKLQLPCNAPFEKLEGPICSSIRLAQQAVCLAACKKLHEMGAFTDTLLPDRGSGEGEKTEQNDEGEPLPGTARHREFYPEGVADILRGEWILSGRDGYQNSQFIKLYMYSVNCVNVGTSKDPFVTQLSNFAIIFGNELDAEVLSTTMDLFVARTMITKASLVFRGRIEITESQLVLLKSFHVRLMSIVLDVDVDPSTTPWDPAKAYLFVPVGAEKCTDPLREIDWTLVNNIVNTDAWNNPLQRARPDVYLGTNERTLGGDRREYGFGKLRHGTAFGQKAHPTYGIRGAIAEFDIVKASGLVPARDRGHFSDYQNQGKLFMADSCWNAKDLAGMVVTAAHSGKRFYVDCICYNMNAENSFPRKEGYLGPLEYSSYADYYKQKYGVELIYRKQPLIRARGVSYCKNLLSPRFEHSDAREGDFSENLDKTYYVYLPPELCLVHPLPGSLVRGAQRLPSIMRRVESMLLAVQLKDIIDYPVPATKILEALTAASCQETLCYERAELLGDAYLKWVVSRFLFLKYPQKHEGQLTRMRQQMVSNMVLYQYALNKTLQSYIQADRFAPSRWAAPGVLPVFDEESREYEPSIFDEESTGCELQKESYDDYADNMQEDGEIEGDSSCYRVLSSKTLADVVEALIGVYYVAGGKIAANHLMKWIGIHAELDPEEIPPPKPYDIPESIMRSINFDTLKGVLGIEFQNKGLLVEAITHASRPSSGVSCYQRLEFVGDAVLDHLITRHLFFTYTDLPPGRLTDLRAAAVNNENFARVAVKHKLHVHLRHGSSALETQIREFVKDVQEELLKPGFNSFGLGDCKAPKVLGDIVESIAGAIFLDSGYDTSVVWKVFQPLLHPMVTPETLPMHPVRELQERCQQQAEGLEYKASRAGNIATVEVFVDGVQIGVAQNPQKKMAQKLAARNALVVLKEKETATKKEDERDGEKKNGAQMFTRQTLNDICLRRQWPMPQYRCVNEGGPAHAKRFVYSVRVNTSDRGWTDECIGEPMPSVKKAKDSAAVLLLELLNRDFPDKPDGKQP
The following text describes a protein:
Function:
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MGKPNKERNQRSTAPRGRGRGRGGFSVARAGGSGRQKALRSGPSGGGAREGMDDEEIFRRVMAGENLDTSSEESDSGSGSGSGSGSEKDDEEDEESSEEEPATIEVPVAMWDFDHCDPKRCSGKKLARHGLINAMRVGQRFRGIVLTPKGKKVISPEDDEIVQMSGLAVVECSWARLDEVPFNKIKSPYERLLPFLIASNPVNYGKPWRLNCVEALAAGFYITGHADWAEVLLAKFSWGHSFYKLNSHLIERYRTCKDADEIKAMQESIQREMEEERVERRRQRDADEGADLLRENPNHQGSEWQTEQDNDSDEERDVVETLIAGLEQANLDDEKAETEGR
The following text describes a protein:
Function:
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Sequence:
MRAARRVGVNRQLIHSVAVTTSKFQSPVTICQTTDPTTEFPVSQDHTGQQAATGPQITLYSTAICPYCVAAKNFLKSKGQTWTEVRIDLDPAERDKMVALAKRTSVPQIFVGDIHVGGYDDMMAMHRAGKLEPLFAAAGGQA
The following text describes a protein:
Function:
Required for precise axonal bifurcation in mushroom body neurons by suppressing ectopic bifurcation and regulating the guidance of sister axons. May function by regulating expression of tdp1. Acts downstream of the serine/threonine-protein kinase Bsk to modulate the direction of axon projection. May play a role in fatty acid metabolism.
Subcellular Localization:
Cell membrane; Peripheral membrane protein.
Sequence:
MEHTASLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNSTNHGNINNDGVIVSSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAPGYENMRPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSEVRQEAVQQALAALKGRPKPSLPMPSKRTSVLNRSPGCNDELDSSTDDESIPEETISPDKEYNYPRDHISNSILPPEPIIKPPIRESSMGSQQHARTDVKQNQITNQKYTAPNSAPERRPPQNLPPLPTSEPLSSDYPPIAYKRENDFSDKAFKQKQYNAPDITQFNNAHRAADRVTRYVNVSQNELNETDANGKWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLSRAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSSDTPPQQVGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTEHLPKPPKEFNVGNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSSLRMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVCGSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRGRIAVFSIKVLRDERVCVIAEQRPDCSEEESFQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLGGIHLCEARRRFLEGSLHPANVLMCPHTCVTNLPKPRELHQGVQTAAKLSSSSGCGITDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAEDCERKPQLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKRAEKIAALLQERGRIEPGDHVALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIKLLKSREAATSIDPKTWPPILDIDDNPKRKYAGIATVSFDSSAYLDFSVSTCGRLSGVNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLSQHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLRCVRTCVVVAEERPRVQLTQQFCKLFQALGLNTRCVSTSFGCRVNPAICVQGASSAESAQVYVDMRALRNNRVALVERGAPNSLCVIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYGDETDYNDHFNAKLVTGATSELYARTGYLGFLRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQELHDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALDLVPLVTNTVLEDHQLIVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
The following text describes a protein:
Function:
Receptor for basic fibroblast growth factor.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Membrane; Single-pass membrane protein.
Sequence:
METRCSPETSLLSYFKFYEDRGQSLAGLVGPMCSSEAEVVGSVSRFLNTVVVSYQSDSPSLSNKDQYPYYFRTFPDTTEQCYALIELFQNFGWGRYALLSDSEDITYKVMKNMEEVMIEGGIEMVVDIYMATNEVNQAAVTSYLEEIVSKKAHIIVGYFPENVARLVLCEAHKQGLTGEKGYQWFLPEWYQDAWWDTDYHNKNSPSYSIFSTSPSSFNISCTTTEMMQAIKGYISLSRAYIANWDKPVPGHETVEGWINEYNSLIEKEGKMPSTYAAYAYDTVWTYAYALDKLLFNDVAALDTLSSQQTIRTYLRHLSNTSFSGVTGEVKFMDQDRRGPISIHQHHPPTTTIIGSYIPDMDTKDQGSLSLNTSGIMWASGSQPTDGANGPTCMVEGLRQALGSDCRTAIALMNTILLLVILVSTIILAVFIKRRYDRKVKRTEQHIKQLTLMGLGEGALITLDEWEMPRENVVLNRKLGEGAFGTVYGGEALLDDNKWAAVAVKTLKLGASVEEKLDFLSEAEVMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTFLLGRRHLVGEGVYERNQHVMCPDQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALYDSDYYRLGKRSKLPVRWMAPESLTEGIFTTMSDVWSLGVVIYEVVTFGSFPYQELSNAEVLDYIRNRNSLRPPEGCSPALGALMMQCWAIQPQHRPTAKDVNDILCQRPHLITPCLGVPLGSIPPEEIHSTGLPLSPVRPKHPAPKHSTRSNSSTEMHMGREFNRIHDDEFLTGHLASVGHIFRASKRRSKNKKSFSRCSFELAPSGSRRLRRDSETERNCISIISSTASAPSTSMSNTSTPSTSQDSCVVAVEDLPPVIHRGRSRTSATLEHNFLHRLPSGGTFTKLLKKAATEDNIYSESESRQHSWSLFSCIDSERFEGLPLLQHQSSRRGSKRPRSKSLGSKSSGSKSPSSKHSLYVTLSRNGFDDSKEEETMISFVSN
The following text describes a protein:
Function:
Not known; does not seem to have catalytic activity.
Subcellular Localization:
Secreted.
Sequence:
MWFRPALVLLPLLCLSLRLSGAQEAETGPPAPGQVPNATQTEDESSDWGLDTIRDSFQAVNGYFDSMLELLGGRNGVCQYRCRFGKAPLPRPDYKTPEPNGCSSYFLGLQLDMGIPAMTKCCNQLDLCYDTCGSNKYRCDSKFRWCLHSICSDLKKSLGFVSKVEACETVADTLFNTVWTLGCKPFMNSQRAACICNEEEKDEL
The following text describes a protein:
Function:
Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.
Miscellaneous:
MISCELLANEOUS: Present with 1520 molecules/cell in log phase SD medium.
Subcellular Localization:
Golgi apparatus.
Sequence:
MAIALWYCPPQGSVAYETLQMLIFSFQTLFPDSPVFEPHVTVTSHLVCNSKDDVNKILTSCVAAIQSIRSHQTAKKGRKGQVSHAVAAPLVSFNGCSVGKQYFKKIVLECNKNKILYGVAQVMREMYVEIDPETRSSRAATWVHEEFHPHVSLLYSDIHPVSQASLRVVQQRIEDALDVQLVPREKRKGSGNADGSNEVQMRWDFDVSSSLSWNIPGTFKVVNCVGPVQEWEVLGRVDV
The following text describes a protein:
Function:
Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). Participates in ovule development.
Subcellular Localization:
Nucleus.
Sequence:
MGLKGYSVGEGGGEIVEVQGGHIIRATGRKDRHSKVFTSKGPRDRRVRLSAHTAIQFYDVQDRLGYDRPSKAVDWLIKKAKTAIDKLELGETTTTTTRQEPVNTKPESPTLVFQRENNDQTQFVAANLDPEDAMKTFFPATTTTNGGGGTNINFQNYPHQDDNNMVSRTTTPPPNLSQDLGLSLHPFQGNNNTVVVPETNNFTTTHFDTFGRISGWNHHDLTMTSSSSSEHQQQEQEERSNGGFMVNHHPHHHHHQPSMMTLLNSQQQQVFLGGQQQQQQRGTLQSSLFPHSFRSWDHHQTTSDHHHHQNQASSMFASSSQYGSHGMMMMQGLSFPNTTRLLHGEEATQPNSSSSPPNSHL
The following text describes a protein:
Function:
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Subcellular Localization:
Nucleus.
Sequence:
MASSSDVRDVLDLPDLEPNDKLTQQPKRQKLAAPVGGKRMDGMQRELFALMGENTPSVSVTKDSHTSLFKDKPQWQAKLTPWMWTPFQNQAREDGLILSHWVRGGELTQGDQYPFAALNTQISFPELTQEDYDGLKLATPGWTLEETRYLMHLCSEFDLRWPVIHDRWEWQTDQDVTMATGETKGAEGTESKVKEEDKDVEMADVKEEKENKDESNKEKSEKKESAPPDGTARTVEDLKERFYNVVSAMSKHPEKYTAEGYNMTTVKFPRDMEIKRKQYLERLLARSPAEIAEEEALILKSRKLELSATKMLQERQELLKLLDAPQPTSSVAQFQTSQGLAHLTSTLNDKSKKGGKPTKEGSVGPQAPDRGGSVEKTTKKEDTKEAKKATKEDKKAATTIAAAISKKLTTKEEAAYGISYHDKLTPGVYLRSSKVTTFKPTIQTKIVAALQDIGIPPKPVMPTAKVCAKFESIQHSMSVLLETKRAADKLETEIRLLRGQKGQL
The following text describes a protein:
Function:
Cadherins are calcium-dependent cell adhesion proteins; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells. Required for proper neurite branching. Required for pre- and postsynaptic organization. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.
Subcellular Localization:
Cell junction, adherens junction. Cell junction, desmosome. Cell membrane, sarcolemma. Cell membrane; Single-pass type I membrane protein. Cell surface.
Sequence:
MCRIAGALRTLLPLLAALFQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKFSNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPTLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAIITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFTPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGDD
The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
Miscellaneous:
MISCELLANEOUS: [Isoform 4]: May be due to a competing donor splice site, to exon inclusion and to intron retention; MISCELLANEOUS: [Isoform 5]: May be due to intron retention.
Subcellular Localization:
Cytoplasm. Cell projection, dendrite. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Synapse. Cytoplasm, cytoskeleton. Note=Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle-associated form. Associated with the cytoskeleton (By similarity). Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum.
Domain:
The coiled coil domain mediates the interaction with the N-terminal t-SNARE domain of SNAP25.
Sequence:
MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
The following text describes a protein:
Function:
Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA).
Subcellular Localization:
Nucleus speckle. Nucleus, nucleoplasm. Cytoplasm. Note=Mainly nuclear with some fraction located in the cytoplasm. ZC3H13 is required to anchor component of the MACOM subcomplex, such as VIRMA, in the nucleus.
Sequence:
MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQLKNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQAGVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPEYENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARITGPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQRCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKNLRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIFQDLLALVRSPGDSVIRQQCVEYVTSILQSLCDQDIALILPSSSEGSISELEQLSNSLPNKELMTSICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVSTFSKDTGELASSFLEFMRQILNSDTIGCCGDDNGLMEVEGAHTSRTMSINAAELKQLLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDSVVGLKQMLESSGDPLPLSDQDVEPVLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCCSDFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVSQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASANSGSGGSRGKFVSGGSGRGRHVRSFTR