lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA.
Miscellaneous:
MISCELLANEOUS: Present with 358 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Domain:
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Sequence:
METIDSKQNINRESLLEERRKKLAKWKQKKAQFDAQKEHQTSRNDIVTNSLEGKQTTEKFTERQERVKEELRKRKNEFRKSDEPVSVKPSKKKSKRSKVKKKISFDFSDDDDSEIGVSFRSKEHIQKAPEHDNEKDPLDEFMTSLKEEKMSNSKGMYDRGDILDVEDQLFELGGTDDEDVEDNTDNSNIAKIAKLKAKKRVKQIYYSPEELEPFQKNFYIESETVSSMSEMEVEELRLSLDNIKIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSLTPIQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGLILAPTRELALQIHEEVTKFTEADTSIRSVCCTGGSEMKKQITDLKRGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEADRLFDLGFEPQITQIMKTVRPDKQCVLFSATFPNKLRSFAVRVLHSPISITINSKGMVNENVKQKFRICHSEDEKFDNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRSGTAITLLLHDELSGAYILSKAMRDEEIKALDPLQAKELQEMSAKFESGMKKGKFRLSKGFGGKGLENIKSKREEAQNKDLELKKNDKRSDDLEKKISNPREGHDSVSESSALIPRLNYELFKESTDGSIIFYAKVYINDLPQIVRWEATKNTTLLFIKHETGCSITNKGKFYPEGKEPKNENDEPKLYLLIEGQDEKDIQLSIELLEQKVKEGVVKAASLSLKSTKY
The following text describes a protein:
Function:
Involved in the initial differentiation of the proplastid during the embryo development and in plastid differentiation linked to cell differentiation, morphogenesis and organogenesis during the plant life cycle.
Miscellaneous:
MISCELLANEOUS: [Isoform 1]: Found predominantly in leaves and inflorescence stems; MISCELLANEOUS: [Isoform 2]: Found predominantly in flower buds and siliques. Seems to be unable to interact with EMB506.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MQSLSTPHTISLLLPRTSPSRLSPSLHSLAFPTRLRSLSYSSQTSILPDAGDDFIVGDCLVYEDGVFEDPYLDKEVTQVAKQERKKNRRGGAKRLDESEIEPENLVPEEWRDIQAEVNLTKKDKRKIAQEMEFGVRVEKKRQGLIPLRKVDLNDFLTYKEAKLAQLRPVILDKPGNFSDDSGASSDGETAVSSPSERVAPKNPRWAVYGKGFDHVAKFFNSDKYDPSDKKSDGPRKLLSKEEKFMLNSRNPDLAVATSKKWLPLHTLAACGEFYLVDSLLKHNLDINATDVGGLTVLHRAIIGKKQAITNYLLRESANPFVLDDEGATLMHYAVQTASAPTIKLLLLYNADINAQDRDGWTPLHVAVQARRSDIVKLLLIKGADIEVKNKDGLTPLGLCLYLGREIRTYEVMKLLKEFPLSRHKKRLVTTDEDIE
The following text describes a protein:
Function:
Acts in association with FDM3 and FDM5 for RNA-directed DNA methylation (RdDM).
Sequence:
MYSRRELEDLEYRYYSEMKDGTRKVKISESLFRCPFCYIDRKRDYQFDDLLRHASGIGGSSRTKDGRDKARHLALERYMRKYLRPRERPRPSPTSDVSSLPKEEFTGKWKSTLSTTEEGEFITTENSSSPHIVKAEPKFVSGDDSGRSGEERLKFSDKPDPFFSNEDKSYPAKRPCLVSGAKEGDEPVQRIGLSHGASFAPTYPQKLVSLGAGNGDQMYVHPWKGILANMKRTFNEKTRKYAGESGSKIREDLIKKGFNPHKVTPLWNGRLGFTGFAIVDFGKEWEGFRNATMFDKHFEVSQCGKRDHDLTRDPGDKLYGWVAKQDDYYSRTAIGDHLRKQGDLKSVSGKEAEDQRKTFTLVSNLENTLVTKSDNLQQMESIYKQTSSVLEKRMKEKDEMINTHNEKMSIMQQTARDYLASIYEEHEKASQHLEAQRKEYEDRENYLDKCQAKNKTERRKLQWQKHKNLMATQEQNKADEDMMRLAEQQQREKDELRKQVRELEEKIDAEQALELEIERMRGDLQVMGHMQEGEGEDSKIKEMIEKTKEELKEKEEDWEYQESLYQTLVVKHGYTNDELQDARKALIRSMRELTTRAYIGVKRMGALDETPFKKVAKEKYPAVEADKKAEELCSLWEEHLGDSAWHPIKVVEKDGIAKEELNEEDEKLQELRKELGEEVYAAVTQALKERNEYNGSGRYIVPELWNFKQNRKASIKEGVVYLVNSWKQKKPKPKRR
The following text describes a protein:
Function:
Malonyltransferase acting on xenobiotic glucosides. Has activity toward 2-Naphthol glucoside (2NAG), 1-Naphthol glucoside (1NAG), kaempferol 7-O-glucoside, kaempferol 3-O-glucoside, hydroxycoumarin glucosides, phenol-glucosides and isoflavone glucoside (daidzin), but not toward 4-coumaroyl glucoside, kaempferol 3,7-O-diglucoside, salicylic acid glucoside and phlorizin. In vivo, seems to be involved in the malonylation of 2-Naphthol glucoside while PMAT2 would be involved in the malonylation of 4-methylumbelliferone glucoside or 4-nitrophenyl glucoside.
Sequence:
MVNEEMESSLKVIDVARVTPSNSDSSESLTLPLTFFDLLWYKLHAVERVIFYKLTDASRPFFDSVIVPNLKTSLSSSLSHYLPLAGKLVWEPLDPKPKIVYTPNDAVSFTVAESNADFSRLTGKEPFPTTELYPLVPELHVSDDSASAVSFQVTLFPNQGFCISVNAHHAVLDGKTTTNFLKSWARTCKNQDSFLPQDLIPVYDRTVIKDPMDLDTKILNAWHRVAKVFTGGKEPENPKSLKLLWSPEIGPDVFRYTLNLTREDIQKLRERLKKESSSSSVSSSPKELRLSTFVIVYSYALTCLIKARGGDPSRPVGYGFAVDCRSLMVPPVPSSYFGNCVSACFKMSLTAETFMSEEGFLAAARMVSDSVEALDENVALKIPEILEGFTTLSPGTQVLSVAGSTRFGVYGLDFGWGRPEKVVVVSIDQGEAISFAESRDGSGGVELGFSLKKHEMDVLVDLLHKGLEN
The following text describes a protein:
Function:
Putative serine/threonine-protein kinase that may be involved in rRNA transcription and ribosome biogenesis.
Miscellaneous:
MISCELLANEOUS: Present with 556 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MSYTNKRHTYYGGFTNDLSDTFQYPQRTDEQRRKHVTFGPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLKPHSSFLSITPDEWDKLNNTQSVFRLAKPRRRYGSRPQSSCSTSSLGSRSDKRDSLVIDSTLITFPAPPQESQNHIITRPASIASDQRLSPIRRSNRHNRSNSAASVALQAVVNADREYVLSHEQSLSPVQNIRQTTGNMTASLSPPPAISPGDIIIETTPIKRNTISGSSIVPSLEEESSTTMQTSKIQPNNMASSQNHQYNKNKTQNSLQSAKNFYRTSSSSHTKPRPTSYHPGSYTTPPYNSNTLSIYEINEKAKSSASSQTLNQRDTSPFDSTPYLALDTCITSSSSIESSPKLITHGQFSVAKPSVDLQSVSGDLIKYKRDADVVTRIYDEKYKQKRKSLRYSGIFSDISCDTVTEESDELRPPESPLQQHEGQESIDKAKTEDTSEKGSKSSNIAKATAQKHVNNHLERSLNEAESTKKRFSFLSLYSYDTSKSSLYSSMDSKRKPSPPSQRRPKKDDSYQTNSKNHYITASNMQTSHQVSKDLPAPTMVQNKCTLETKKAVRSNRSSIMVSEVNKASVDNKAAQSPEHSTAKRVLGFFKRRSMKI
The following text describes a protein:
Function:
Involved in spermatogenesis, specifically in the morphogenesis of fibrous body-membranous organelles (FB-MO), which are Golgi-derived organelles used for transporting sperm-specific components, in spermatocytes and in their localization into budding spermatids. Required for the proper formation of spermatids and spermatozoa.
Subcellular Localization:
Membrane; Multi-pass membrane protein. Note=Mainly found in fibrous body-membranous organelles.
Domain:
The DHHC domain is required for palmitoyltransferase activity.
Sequence:
MSWYSKIYVAVREYRAKHKITGWILTRCLNVLLFIQLILLWWSLYMYVTVTIGYYVQSTIQATIYLIVGSFLFVMSMWSLAKTLFTRVGRVPERYRPSKELEDRLKAVTPMEKNRYVVEKSTPEQLAQQNTILEEMCTYCKVVVAECDQVGRLKYCYECGHIKPDRARHCSSCGKCCIKYDHHCPWINMCVTHVNYKYFLLYIIYTSFLVYWYLLTSLEGAVRYFINQQWTDELGKFLFYLFSFIVGGVFGYYPLGELIIFHYQLISLNETTVEQTKPALLRFDNAADYNMGKYNNFQSVFGWGLWLCPIDSSTQDGLHFDIRYVNTQQRNRFVRIEEEPSSTQSSQSSIQ
The following text describes a protein:
Function:
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Subcellular Localization:
Cytoplasm, cytoskeleton.
Sequence:
MPLVRLELRNEFGLGNPDLFQNASRIVDPNEVLDGVAISGLVGILRQLGDLAVFASEIFSNLHEQVVATSALGHKLVARLKRIETVLPKIENAVQNQKSHIYFARIPGHVWHCNIEIEHYHFLGNNLPQFIMDYYEECHNPPRLFMLDKFDRAGSGSCLKRYSDPTYFRRTMTGLEMIKEEKIKNENKTDIYKWKETRMLSKKIRHAISLSHYNSSFARALYKIYNLISSVQSNSMGTNEQRTTEGTIPACDIRSKSDIGSRTMPSNLTTNFSCKKTFLDTSSSVEPEKLTLIEPKSKSKTNNDEDWVSEEIASTSDIKQTSNLEIRSRSFNTWKTTNFIYEKQLANANSSADTNSLSEPGEASFNKPLESSTKIDDDEEYDSAGNNSLSDTITENGQSERTQFYGYKSFHVSESPMYLSSQLKQKNGNDKNGQSDQEEIQVHIGSISLPDDQSASLAKTIHHDEVTNEVENYLDTRYAFESEMETDTDSEFQTTREAKSSSIKTNQAGSMADNMQKMDISESDSIEDSYSSMSENFHEESSPKHSNSISFEIVNNFNAASLGRDENISVGIDFNGSKEIYLSKSSGKNEFSDEQYSQFSTIDVQSQSSLSNINNLLFEDEQIVDSDNAREICEFSEEPSIKISTNGGILGLKSPKPINEVASTYGVSTDGCKCSRIVISNELDNNRSLEKDEIVVLDCSKTGHDNFQKLKCTTVCRKEPNLFRSELAHCENEFPAALVKVSSDELCPKNTRISSSPPALATGFLEKNIMHNSAITKHDQSQPFSITPTSNALVLREKSYGNVPSQQCQYGMKQIEETISSRSQYHGSSSSASPPLEDMKISFHPINSMVASTLKMEFPDSHLRKNIEEIMFPSFQILQVSSVSTDHLVFDSDDETFYKSSPSCSENFIDHHSDSDFEVWELEDRSVIRNHDVNALHPVLSSNASISNSSDLSKMNHCLLQNESDHENLTIDENDTTTFQSGHATDLPCLDFWKTLDTKQEGKYDPGIPGNSESEDCPSSCTNEKAVSSPVPPCSHLENKQHCLSENTNSSVDPDLDPKRSIKQTEQVVCMRPELLEPIQVEKRKLHCSMSMIDCNEMNGNHEEVAKTEVDKEMGEFLHELRSKSFNLRRTVIAKSDFAPRPTTNSKIAAILEKAEAIRQVEVGDDDDEGCGSWSDY
The following text describes a protein:
Function:
Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
Sequence:
MAGDEKGEELILRVFSANSISVKCEEPPTVRWRTLEPRKEDGLSKVKFRAGSSNVIRPTRVRIVALNPSQFAAALRCSLVWMSGKGSEKPHCEHRGRCLEAGLNRAFQAARPVVRVYAITEDTWRQVLEFSRVVHEDLSNYDPEGAWPVLVDEFVDHMYRKSSCFQKLVMLLHCGSLRLRSECSAELFGSFGCYLSIEPSEYTTRQENSLPL
The following text describes a protein:
Function:
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Subcellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Sequence:
MDFRRQTLVSNGGSSQPQPSVPSSAIKKASRLGPARQSLAPSQIQSRTSILGVSNSQENASHGMMGSRKSTVPGKMGDRDQLMSASRGDGGIYGRTPQMNRGIPGSVRRSSVFTSNSQGRTSMAPGVYSTAYKDPRPLRDKVFQSNCMRNVNEYLISVRYPLPLTAKTLTSPTAKEFQSIFKFLVNDLVDPGAAWGKKFEDDTLSILKDLKYPGMDSVSKTALTAPGAPQSWPNMLAMLNWLVDLCKALDNWDDPEIISDPLMVPATELPLDYPNLDDRLLWDFAAKTYSQWFDGEAEEFDEAEQELEHAYGKSYSIVLNDTEQATDRMASATVAECEKLEREIQKRNVEIQQLHVQEVCSPITDRISFADKSYKPPLKKLEDEYVQLMSDKNKFISFLDQQGQKIEKIRLRISKVKEAVISQEAELEARQSELAHIEQAVAAQNLSPDEVQRMNHERDSLTRSLEDLRNKISEASQFAYDQEMVVTKSMDRFEGLLTDYNSLAHQIGLLDFSLDVPSLAANVNYNLDVDLGAEELEEVKAVGVRMRSTIWQALQTCREMFRQEALGLGNGTIALEDEFDKLGQSVERQKEEVGNLEVRLKIVHNQAEDAQSQIASENSDTNKIITQLETEVTNMLAASQQGVLSTQSQLESTRIAFKELRHKTALFQDSVVAEVGEHIDAIIKAKEHTANSLKSIRALAETQ
The following text describes a protein:
Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
Sequence:
MSFKEGSKFPAGVEFSYIPIQLDDLELINPLKCDVASQLKLDNLLTKLSTTDTPNLLIVSVPGAFTPTCTESHLPPYLENLAKLHDKKIGAIVVLATNDQFVVNAWGKVLIKAYVKTSGKFPEVIFASDGGFSEKYGLAGDRGGIIRNKRYAAVIDSKTKDVVYLGVETEKGVQSSGIDAVLAKL
The following text describes a protein:
Function:
Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids.
Subcellular Localization:
Lysosome.
Sequence:
MLLKTVLLLALVAQVLMLENGLLRKPPMGWLAWERFRCNIDCDEDPKNCISERLFMEMADRLAQDGWRDLGYVYLNIDDCWIGGRDAKGNLMPDPKRFPHGIAFLADYAHSLGLKLGIYEDLGSFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFSTHKERAEGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILDWFVAHQDILQPVAGPGHWNDPDMLLIGNFGLSFEQAQSQMALWTVLAAPLFMSTDLRTISAQNVDILQNTLMIKINQDPLGIQGRRVLKEKSFIDVFMRPLANEACALVFFSRRTDMPYRYHCSLGRLNFTAPECMRPRTSTRATSSVASTLQPTSR
The following text describes a protein:
Function:
Inhibits peptide loading of MHC class I molecules by transporters associated with antigen processing (TAP). Does not prevent peptide binding to TAP, but binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1, but not TAP2. Also prevents the conformational rearrangement of TAP induced by peptide binding. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
Subcellular Localization:
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Domain:
The ER-lumenal domain is responsible for TAP inhibition. It is sufficient to inhibit ATP binding to TAP.
Sequence:
MDLLIRLGFLLMCALPTPGERSSRDPKTLLSLSPRQQACVPRTKSHRPVCYNDTGDCTDADDSWKQLGEDFAHQCLQAAKKRPKTHKSRPNDRNLEGRLTCQRVRRLLPCDLDIHPSHRLLTLMNNCVCDGAVWNAFRLIERHGFFAVTLYLCCGITLLVVILALLCSITYESTGRGIRRCGS
The following text describes a protein:
Function:
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
Subcellular Localization:
Membrane; Multi-pass membrane protein.
Sequence:
MSAKPRPVYLDLPNIRLPIPGIVSILHRISGVGLFIMLPFLLYFLSGTLSQESAFETYRAIVSHPLVKLVLIGVLWAYLHHSLAGIRFLFLDAHKGLELNTARNTAKAVFASALVLTVVLGALLW
The following text describes a protein:
Function:
Located at the 30S-50S ribosomal subunit interface and binds directly to 23S ribosomal RNA.
Sequence:
MATSSRLLPQALHMLPRIPTKNLRVSSFIPSLNSQISFSTVSLTHSGSNFGFAIDSRKRREFIAKAEESTEGEDTEEAVTEDVAETEGATEVEEAKTPWKPRTKLGDVMGILNQKAIEVSEKVRPVPEIRTGDIVEIKLEVPENRRRLSIYKGIVMSRQNAGIHTTIRIRRIIAGIGVEIVFPIYSPNIKEIKVVSHRKVRRARLYYLRDKLPRLSTFK
The following text describes a protein:
Function:
Required for meiosis and spore formation. Seems to be involved in the coordinate induction of late meiotic events.
Subcellular Localization:
Cytoplasm.
Sequence:
MTIHQGGNSVIDNVPYSLNTNVNDSIYSEKGTGRKDAEDHTPSKITDLEKNVDHSIPSFPENDPKNYSEFVNLNPPKRPDLEHTRGSSWHTASENVNDLAANDSTRVQTPEFITQTMEDENVEVPPLERDERDAAAAHTSKANRNSARQMWAQLMASVRKFKREDEKPILKENLPAINLFEAGIPASLPIAKHFIRDKSGQPVLPIITDLIKVSVLDVEPKHNRIHSTFTIQVEYGTGPHAIRWLIYRQLRDFINLHSHFLFFEFQHRFSGRRMKLPKFPKEVLPYLVKLRGYQKILYSNPSDQLIDETHSISDISWESHSQDGDRTTGQPRHANNGRKKHGNFWTIQGNTLGVYLQEMIHNLQFFPEVNVLYSFLEFSSLGLYLAGAGTFHGKEGFATLKRNYSPTQYMLCCNTTMMKTRSQPFWIIVSESCIILCDNMLSMQPADVFIWDVDFEITRKNFRKAHSKDTNEKIRLSHHSFKIKNRQKVMKLSVRSGRWLQQFINSVQVAQGLTAWCEIHRFDSFAPVRTNVAVQWMVDARDHMWNVSRAIKNAKRCIMIHGWWLSPELQMRRPYSMAHKWRIDRILNEKAHEGVMVYIMIYRNIDATIPIDSFHTKEHLQSLHPNIYVIRSPSHFRQNALFWAHHEKLVVVDDAITFIGGIDLCFGRYDTPQHILYDDKPVADKTGLCEQTWRGKDYSNARVHDFFDLTEPYKDMYDRLAVPRMGWHDVSMCIIGQPARDAARHFVQRWNYLIQCKKPARKTPLLIPPPDFTTDQLTDSQLTGTCEVQVLRSAGLWSLGLVDTVEQSIQNAYVTCIEKSEHFIYIENQFFVTSTTCEGTTIENRVGDALVERIIRAHKNNEKWRGVIMIPLLPGFEGQIDLQEGGSLRLIVECQYRSICHGEHSIFGRLNAKGIDGSKYLRFYGLRGWAHLGENHELVTEMIYVHAKILIADDRVAVIGSANINERSLLGNRDSEIAAVIRDTLTIDSKMDGKPYKVGKFAHTLRKRLMREHLGLETDVLEQREYNMDGLDRDTEWKRVEVWTPDEGNAINGSAYTAEELKMKYRSQSQFTTTPDILRKAEKSMKKLDQRVSLIPSSIEFNIKTQKDKVEFEKNYEKSKKGPDVIANALVGGIPLSLKTKEDSLYELSKFSQCGEDQRPMVLKDPDHLVPEPSRPHCGNGLVFYDDIPLLEVNPISGETIPKFDASSFEDPVCDEFFEDIWSKVASNNTTIYRHIFRCVPDDEMLTWESYNEWKKYGKRFKEEQARWRQEELSNLHETHEKSENDPKNPKAGSQGSGNTSASEDSKTEKPKTRTNNGLQVPDKRVVYDLLRGIRGQLVELPLKWMSTESNARNWLSSIDKIPPLEIYD
The following text describes a protein:
Function:
Necessary for correct organization of Golgi apparatus. Involved in bone development.
Subcellular Localization:
Cytoplasm. Golgi apparatus. Membrane; Lipid-anchor. Note=Sequence analysis programs predict 1 transmembrane region. However, it has been shown in human that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol (By similarity).
Sequence:
MGSNSSKISDLPKNEYLKRLSGPEAISENDPFWNQLFSFSFSAPTSSTELKLLEEATISVCKSLVENNPRTGNLAALTKVFLARTRELRLSAECQNHIFIWQTHNALFIICCLLKVFICEMSEEELQLHFTYEEKLPGTYTLCVLLGSDSEDLLEELLCSLIQLITDTPLLDITYEISVEAISAMIVFLSCQLFHKEVLRQSISHKYLMQGPCLPYTSKLVKTLLYNFIRQEKPPPPGTHVFPQQSDGGGLLYGLASGVATGLWTVFTLGGVGSKAASPELTSPLANQSLLLLLVLVNLTDAPDIPNPYRQAVTSFKNTQDSSPFPSSVPHTFQINFNSLYTTLCEQQTSDQATLLLYTLLHQNANVRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLSSSDVPLPDYAQDLSVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLLQSGAELSVERVLEIIKQGVVALPKDRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAVGLYWNPQDIQLFAMDSD
The following text describes a protein:
Function:
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells.
Subcellular Localization:
Nucleus.
Sequence:
MDVFLWIRRHKSSIFTDAKESTTVFELKKIIEGIMKKPPEDQRLYKDDVILEDNKTLGDCGFTSQSAKAQSPATVGLAFRQDDGEFENLFVAPLSTPPELPDVMKPQEQPGTQDQNVQ
The following text describes a protein:
Function:
Mitochondrial heat soluble protein acting as a molecular shield in water-deficient condition.
Subcellular Localization:
Mitochondrion.
Domain:
Contiguous repeats of the 11-mer LEA motif is characteristic of group 3 LEA proteins and form an amphipathic helical structure under water-deficient conditions.
Sequence:
MFLARNVSRVALRSASLSPAAIPQQQHAGVAAVYAVRFASSSGSGRPADNWAESQKEKAKAGLKDAQAEVGKVAREVKDKAAGGIEQAKDAVKQGANDLKRSGSRTFENAKDDIQAKAQHAKSDLKGAKHQAEGVVENVKEAAENAWEKTKDVAENLKDKVQSPGGLADKAANAWETVKDRAQDAASEVKHKAGDLKDKAQQVIHDATTQSGDNRKQDQQQRRDSQGSQSGQNSRSRN
The following text describes a protein:
Function:
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Subcellular Localization:
Chromosome, centromere. Nucleus.
Sequence:
MANSTRSLLESSYDIGPCDSTQSSSIVEQLQAVKDKEICMVDFRNCIVFQCITCNTVLGDSLGVCGEVESSQSVICLKVTEDVMVNEKHEMCSSGQLASSTYQTLLCTGCHDAVGLVLHSTPKHLSALRNLFLLRKELINCYILRSGTCVKASKINFKHRLMDKNIKKLKEYLETKLKQVDILEQMMEKMCTHDVN
The following text describes a protein:
Function:
Single-stranded DNA-binding protein that associates with mitochondrial DNA and may play a role in the regulation of the gene expression machinery. Also seems to be required to prevent break-induced DNA rearrangements in the mitochondrial genome. Can bind to melt double-stranded DNA in vivo.
Miscellaneous:
MISCELLANEOUS: Plants over-expressing WHY2 are small with dark-green distorted leaves, exhibit early senescence and produces shorter siliques with half the amount of seeds found in wild-type plants.
Subcellular Localization:
Mitochondrion.
Sequence:
MMKQARSLLSRSLCDQSKSLFEASTLRGFASWSNSSTPGRGFPGKDAAKPSGRLFAPYSIFKGKAALSVEPVLPSFTEIDSGNLRIDRRGSLMMTFMPAIGERKYDWEKKQKFALSPTEVGSLISMGSKDSSEFFHDPSMKSSNAGQVRKSLSVKPHADGSGYFISLSVNNSILKTNDYFVVPVTKAEFAVMKTAFSFALPHIMGWNRLTGHVNTEALPSRNVSHLKTEPQLELEWDK
The following text describes a protein:
Function:
Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
Sequence:
MKESEKELFEKMLDASFKKKKAMEAGTKITAIVNSAKKDFVFVTAKEGKLPGIISSEEFMESGLPNPGEELEAYFLKEDHGDVHFTTCLSGDLLNKDLLEIAKKAEIPVLGQFVSEGDSGADVKIGEFSGFCPFSQIDPELKKSGLIGKRLKFLIQDFGNRNKLVVSQKKISDRAKEAKLGVLKQELKEGMFVTCKVKTIQNFGLIVEMDGGVTALVPISEATYKKNPELEKEFQVGQTLRARVLRIDWENQKFALTVKDFLKDPWAQTVPFKEGDIVKGTIDSLKPFGVFVKLDDHFNGLVPGRETGISNRVPLSQSFKPGEVVDVFVMEVNPEKKQISLSIQKAKEIQERMDYSSYLSVDTSGSTSSFGAILQNSLNKNKKK
The following text describes a protein:
Function:
Hydrolytic enzyme with a broad substrate specificity acting on phosphate diesters and phosphonate monoesters. Hydrolyzes phosphate mono- and triesters, sulfate monoesters and sulfonate monoesters. Hydrolyzes glyphosate monoesters. Does not hydrolyze DNA or cGMP. Hydrolyzes glyceryl glyphosate, but this substrate has a much lower affinity than the glyphosate monoesters.
Sequence:
MTRKNVLLIVVDQWRADFIPHLMRAEGREPFLKTPNLDRLCREGLTFRNHVTTCVPCGPARASLLTGLYLMNHRAVQNTVPLDQRHLNLGKALRAIGYDPALIGYTTTTPDPRTTSARDPRFTVLGDIMDGFRSVGAFEPNMEGYFGWVAQNGFELPENREDIWLPEGEHSVPGATDKPSRIPKEFSDSTFFTERALTYLKGRDGKPFFLHLGYYRPHPPFVASAPYHAMYKAEDMPAPIRAENPDAEAAQHPLMKHYIDHIRRGSFFHGAEGSGATLDEGEIRQMRATYCGLITEIDDCLGRVFAYLDETGQWDDTLIIFTSDHGEQLGDHHLLGKIGYNAESFRIPLVIKDAGQNRHAGQIEEGFSESIDVMPTILEWLGGETPRACDGRSLLPFLAEGKPSDWRTELHYEFDFRDVFYDQPQNSVQLSQDDCSLCVIEDENYKYVHFAALPPLFFDLKADPHEFSNLAGDPAYAALVRDYAQKALSWRLSHADRTLTHYRSSPQGLTTRNH
The following text describes a protein:
Function:
Has an integral role during the infection of macrophages in the mammalian host.
Subcellular Localization:
Membrane.
Sequence:
MSVDSSSTHRRRCVAARLVRLAAAGAAVTVAVGTAAAWAHAGALQHRCVHDAMQARVRQSVADHHKAPGAVSAVGLPYVTLDAAHTAAAADPRPGSARSVVRDVNWGALRIAVSTEDLTDPAYHCARVGQHVKDHAGAIVTCTAEDILTNEKRDILVKHLIPQAVQLHTERLKVQQVQGKWKVTDMVGDICGDFKVPQAHITEGFSNTDFVMYVASVPSEEGVLAWATTCQTFSDGHPAVGVINIPAANIASRYDQLVTRVVTHEMAHALGFSGPFFEDARIVASVPNVRGKNFDVPVINSSTAVAKAREQYGCDTLEYLEVEDQGGAGSAGSHIKMRNAQDELMAPAAAAGYYTALTMAIFQDLGFYQADFSKAEVMPWGQNAGCAFLTNKCMEQSVTQWPAMFCNESEDAIRCPTSRLSLGACGVTRHPGLPPYWQYFTDPSLAGLSAFMDYCPVVVPYSDGSCTQRASEAHASLLPFNVFSDAARCIDGAFRPKATNGIVKSYAGLCANVQCDTATRTYSVQVHGSNDYTNCTPGLRVELSTVSNAFEGGGYITCPPYVEVCQGNVQAAKDGGNTAAGRRGPRAAATALLVAALLTVAL
The following text describes a protein:
Function:
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
Subcellular Localization:
Mitochondrion.
Sequence:
MWLQYVRRAGPLGRLLTRPPFRPSAPPDRRISTSRNSCPLSSLTTVKQPRLILGIETSCDDSCASIVSSDRTILSSIVTKQDHSSTGGIHPLSAALGHHSNLASTIAAAIEQARITASDLHAIAVTQGPGMASSLGVGLSAAKTLSAVLHIPLIYVHHMQAHALTPLLTEPDPPKLPFLVLLVSGGHTMLVLARSVTHFRILATTSDDSIGDAFDKVARDLGIPWTSAPGAALEALAARAEAHGDGLVFPTPCKGQPTFSYSGLKAAVQRHIASCSPDAMAESAKSSIAAAFQRAACAQLEDKLSMVLRPSHVSQDSRHRPFARIELLDGVSSDDVKTVVCSGGVASNAFIRSRLREHLDRLGRTDVDLQFPPLSLCTDNAAMIAWVGHLIYHQRTRDYTRHARPKWSLQDIPQ
The following text describes a protein:
Function:
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
Subcellular Localization:
Cytoplasm.
Sequence:
MVNEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGVSTIYKPLLGEDCRRTMDIFRLLGVEIKEDDEKLVVTSPGYQSFNTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGINYQMEVASAQVKSAILFASLFSKEPTIIKELDVSRNHTETMFKHFNIPIEAEGLSINTTPEAIRYIKPADFHVPGDISSAAFFIVAALITPGSDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELPVIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASLLSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG
The following text describes a protein:
Function:
Involved in resistance to cisplatin.
Miscellaneous:
MISCELLANEOUS: Present with 1140 molecules/cell in log phase SD medium.
Subcellular Localization:
Cytoplasm.
Sequence:
MATFNPQNEMENQARVQEYKVSTGRGGAGNIHKSMSKPSPVLLPLKSNSKTVANNNNNGSNQEKVPRFAIGRGGAGNIFHDPHLTRSAQQLDSNDNINYNDVINDIDDYISPITSDMVDEGGSNPVTNTRSRISATRSHQSLHATTSSPNNNAPIVVGRGGAGNIFFNKKKVASNGGNEEDEIRGGNIEDEDTINANEDNLFVVTSNGNALAAIKSTSKKPKNKLKGKSAPEKFAIGRGGAGNIISPKSSRNTINHNLNDDDEDKFNLKDDNGKEKKKKKKKKSGFFSSLKTMFN
The following text describes a protein:
Function:
Plays a role in the regulation of imprinted gene expression, regulates repressive epigenetic modifications associated with SETDB1. Required for the recruitment or accumulation of SETDB1 to the endogenous retroviruses (ERVs) and maintenance of repressive chromatin configuration, contributing to a subset of the SETDB1-dependent ERV silencing in embryonic stem cells.
Subcellular Localization:
Nucleus. Note=Localizes around gamma-tubulin during M phase.
Sequence:
MNWNTKQENVPKPPPYSKTQSSILQHFLMTSTTSQSSFNYSPHNQEASQTSFNYSLHNQEACMYSGNSNSVSQPLLSGRNYITPQTQISVSNMPTRTIVASQSSMERVVSTNGKGPQQPNHNLQTVSSGIMQNVWLPSHTEATISHNPDGGTNMPYMHPPQNQLVTSDTYSMQLQMAPLHSGKVPMTHQGSQGLNHFIPDQLVDWTQYTSNELSYPEYRPPPKQYSYILPATTSLQVKNNQLPTYTQSLQSKHSVPLSSHQYAAEASKRLSALPYSCRYENQHVQNAQPVSKHLPMEVPQSSEVHSSEKKKDTYRGFKQQWQNPNEKVSIGQFSEVKINIKQPYSESVRPSGDGVQALVQNNQEKRKYTYNPNTNQVIDTNATKEKLVRDIKSLVEIKKKFSELARKIKINKSLLMAAGCSKTANTSYTEPIQHSEFSAKEMSAKNGNDCSMELLATCLSLWKNQPSKTTEENVPKPLEEKQCNTSRISTTVVGSANPTNEVHVKSLCSGVGNSQKMMSSSQTVLPVLIPSCESSGVAVGKGTELQIAVVSPLVLSDTNTLPGKDSVPEVLPETLYPVVKEGSVCSLQTQPTETVALPFDVIGAVASNNISAEIPLPVDKEKQHKPIQGDPDIADSSLGKHSPLGTEVLPKPMDSTIVSGPMLQIESICSLAEGDVSYNSQIAEIFNSVQTEPQKPSPNQVIDSQQEQVYDTTENKDFSLQKDKCVQCTDVPHEVPEQPEPLQPEEPASSEYVEANREATEESCREYTGRKESTAKDVCLPAAIQQDPHPRETDMFSKSDHSLPAINEINDESEPISYLHDQLSELLKEFPYGIETFNRHEVSLDQQKTHKIVENQTGGKTSNVSGDSTDQIKITVLNSEQIKELFPEDDQPCDKLAEPENKEIVAEVKSPCDSQIPREESHDLGMLDPEKDKIHCCALGWLSMVYEGVPQCHCSSTEKKEKDQCLDINSSKQGEQPCNSGITIFEINPVSNNSKTPLTQATEEGHFSAVHGEKTKASKTKDNREGQELACHFSAKCYKKDKKGNFKIRHDTSLKMEQKLKNISSKCDIPNPSKCNKIAAPEILHVTTSNSAKNMPFSKQASQESLQKKHTSQDLGPVKAPIELSSNTDPCRSNTSSVQSVSPEKKKLKFKAGGSRLKYFEKRKTDHVIIPDVEIKKKKYEKQEQNKNAGDTLKLCSILTESNERASVQEKTVPSPESSDPKGSSSKSTRVITVQEYLQRQKDKQITGNNASRNICVETVLCDSGHTKTSKHSAAVSWGKLVEGQSISAETAKELEHNSSSHGKDFKIHHSEASRTHSVSNNNKGKFDGKQPDKMFKNKTSMNNESNQMPLQVKEQRKQYLNRVAFKCTERESICLTKLDSASKKLSIEKKSGEYTSKTKDTDKPSMLEFKLCPDVLLKNTSTVDKQDCPGPGPEKEQAPVQVSGIKSTKEDWLKCIPTRTKMPESSQRDSADSRLSKRSLSADEFEILQNPVKESNIMFRTYKKMYLEKRSRSLGSSPVK
The following text describes a protein:
Function:
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Localization:
Nucleus.
Domain:
The F-box is necessary for the interaction with ASK proteins.
Sequence:
MEEDCEFRHWDELIPDALGLIFSHLPLQEVLTVVPRVCKAWNRAVTGPYCWQEIDIELWSNRFHQSDHLDRMLEMLIPRSAGSLRKLSVTGLRNDSIFSFIAQHAGSLKTLKVPRSGLTNSGVVNVAEKLSSLTFLDLSYCCKIGPEAIQAIGKHCKSLREFCRNMHPLDVASVVSHDDEAYAIANTMPKLKRLEIAYHRVSTEGVLKILSCCVFLEFLELRGCWDVQLDNKFFKEKFPDMKVLGPRVIGFYDMINDWEDCCSDYFSDGSDYLAWEFFEDGVMGEFYEDEFEHGWDDNFYAENAVLDMEPHIWPPSP