lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters (By similarity). Influences the expression of nuclear encoded chloroplast-targeted genes. Regulates chloroplast development and promotes chlorophyll accumulation. Modulates plant architecture (e.g. height, length and width of leaf blades, and flowering tillers production) and represses tillering, probably by modulating number of cells. Promotes senescence. Involved in grain filling, panicle development and starch production.
Subcellular Localization:
Nucleus.
Sequence:
MSTIYMSQLPATLPLMEGDQDQGLYPAFHRAKDPPILFPFMIDSAVEHQGQIYGDQGLRRQQVLGESNQQFNDHMMMGGSDVFLTPSPFRPTIQSIGSDMIQRSSYDPYDIESNNKQHANGSTSKWMSTPPMKMRIIRKGAATDPEGGAVRKPRRRAQAHQDESQQQLQQALGVVRVCSDCNTTKTPLWRSGPCGPKSLCNACGIRQRKARRAMAAAANGGAAVAPAKSVAAAPVNNKPAAKKEKRAADVDRSLPFKKRCKMVDHVAAAVAATKPTAAGEVVAAAPKDQDHVIVVGGENAAATSMPAQNPISKAAATAAAAAASPAFFHGLPRDEITDAAMLLMTLSCGLVHS
The following text describes a protein:
Function:
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Subcellular Localization:
Nucleus, nucleolus.
Sequence:
MPKKGKQADVTKEEHNLYKRMKVDAVCAVSSLNFDSPEGLFESLISPIGTKEFFQEYWEQKPLLIQRDDPSIAAYYQSLFRLMDLKGLCSRGMFYGRDVNVCRCVNGKKKVLNKGGKVNYLLLRKDFDQKRATIQFHQPQRFKDELWRIQEKLECYFGSLVGSNVYITPPGSQGLPPHYDDVEVFILQLEGEKHWRLYQPTVHLAREYNVEPEDKIGSPTHEFTLKPGDLLYFPRGTIHQADTPPGVAHSTHVTISTYQNNSWGDFLLDIIPGLVFETAKEEVELRMGIPRQQLMQVEAAAVSTTKLCGFLRTLADQLESTRELRSSDMKKDFIMNRLPPYPLAGGFDLSTPVGELPKLDSKVKLQFKDKIIITVEQDQNRSDGIEEKMVYIYHSLKNRRETHMMGNEEETETHGLRFPLSHMDALKQIWSSGVIGVKELKLNTDAEKENLVVSLWTECLIEVV
The following text describes a protein:
Function:
Probably functions as part of the RQC trigger (RQT) complex that activates the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation.
Subcellular Localization:
Cytoplasm, cytosol.
Sequence:
MEKWTKENVLKILPVDDESAAMITSTALAVDSSEAAKDYWISLLGDSAETIEFISDFNQKRFHSTHSGNSPSIMKNKKNVTPNNNIRQKNTATSSHPSFYIANNKQKGYDEEMYKVNPASRNKSQSNNISSHEKSSKTTKNVSPGVMTSDLIPEKKSVKHNNSSSNRIEGLADIEKAIRQIEISQNINKAERRVCNCQGRKHPLNEAAPNCLNCGKIICIVEGIGPCTFCDNPVISKAQQLELIQELKHEGSRLKQAANQKRKSKTVSSKNNFQRLQNSSLHSIFLDPKQLEQKAQEAEERKNVLLNFDRTSAQRTRIIDEAADFDPTSLASDTWASPAEKALNLVRMQKAMAKKEKKKKKVLSISLSGKKVVVDQKEASSESSDEDQDELDNLTKVEGQSHSHNPKAPVIRNLPRPIYHQDLHSSHVAVPESILNKINQKWSKVQDDDGMPSML
The following text describes a protein:
Function:
Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSITETEQRCNELRNDLKLWEKNFAAQNDGRKAGRDDIKANEEISNKYKEYNKLRGKLTAQSAPQTPSKRTASRKATRDAERTPKAAPKYQTSTPLKRKRAEELASEPIPQSPEFLSPQGPSVIGPTPQRDGIVLGLFDMLPAGTPSKRRAVLGDVELNILQTPSRRSQEAASETSLESRARGERTPVSVGKRFMLNQFVTPKKRKMEEEGTPSSTTRGLATPAFLRRGNLLGPIDEADETTPRPAPWKRRGLGRSLSAMIQAMKKDEDDKLDEEADIMREMEMEEAGISMPPKKLRVPQILVEDSQAAMPLGPDRGLETEEDEDEEPELGPDGKPRRVWKKKGLKRQTRRVIMRPNFIKSKLESALQLHDDSEDDQDKVAETQATGHAADDVDSEDDISDYASDVSHTPKQRKVQKKKTEEVKDQPKEGGVKTAARKIKATAHANFRRLKIKSSTGAKGGAKGKFGRRR
The following text describes a protein:
Function:
Transcriptional coactivator for crh-1, the homolog of vertebrate transcription factor CREB1. Regulates the transcription of metabolic genes and may have a role in mitochondrial dynamics and metabolism. Involved in modulation of lifespan. Through crh-1, counteracts the pro-lifespan-extension signals of AMPK both cell autonomously and, when expressed in neurons, at a systemic level, possibly using the catecholamine analog, octopamine, as a messenger.
Subcellular Localization:
Nucleus. Cytoplasm, cytosol. Note=Localization is phosphorylation-dependent with the phosphorylated form translocating to the cytosol. Cytosolic sequestration requires 14-3-3 proteins fft-1 and fft-2. Cytosolic sequestration is partially dependent upon mitochondrial electron transport complex III component isp-1, perhaps as a result of a retrograde signaling pathway relaying signals from mitochondria to the nucleus. Nuclear localization may in part depend on activity of the calcineurin subunit tax-6 and its regulator rcan-1 in response to changes in intracellular calcium levels.
Sequence:
MSNSNTPRKFSEKIAILERKQNEENTTFEDIMRQVQSITHHPTDSSGSSTATAPMPIPQQGLLPPQQPWGHNLGGSLPNVHQMPSYSPPQWPPNWQHEIQHRPIQGHRSRSPEDHMIGSASGSPSHHYHPYGMRSNGLSRSPDRTPPQHPQYTPYGPPYNQPGQLVPPESWNQINRARSDPAIHNMGGMVPMHPHHHQQQQMAFHQMPHYLQNSMPGPSGMMAPNSQSQQHSPQLTPQGSQQGSPVQMHHQIPPPLQMGNNQQMGGGNNGMSPLQSPNHMMTPMYGYHNGSPLHSPMDSPHASTLMLDGSGTPSPYMEVSPPGMHDFNQDAGSLPNLQNVQQQQQQQQEIYTNGGAPGGGYYHAPIGPRHSTGACGPRLVPGPALTPESQSAPTSPHNQLDPNQPPMWPTRTFSNSPEALDIPKLTITNAEGAPGHHVDSYNDFNDLGLDSLDSVLCNGAPPQTISNHQTPNNSFHDPGGTQMLQN
The following text describes a protein:
Function:
FMRFamides and FMRFamide-like peptides are neuropeptides; KPSFVRF-amide: Has no effect on somatic body wall muscle, inhibits contraction of vaginal vera muscle, and inhibits the activity of the dissected pharyngeal myogenic muscle system. Acts as a ligand for the npr-22 receptor in vitro.
Subcellular Localization:
Secreted.
Sequence:
MNQFYALFLVACIAAMANAYEEPDLDALAEFCGKESNRKYCDQIAQLATQHAIGINQEQVRMEKRKPSFVRFGKRSGYPLVIDDEEMRMDKRKPSFVRFGRK
The following text describes a protein:
Function:
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
Subcellular Localization:
Cytoplasmic granule. Nucleus, nucleolus.
Sequence:
MAENREPRGAVEAELDPVEYTLRKRLPHRLPRRPNDIYVNMKTDFKAQLARCQKLLDGGARGQNSCSEIYIHGLGLAINRAINIALQLQAGSFGSLQVAANTSTVELVDELEPETDTREPLTRIRNNSAIHIRVFRVTPK
The following text describes a protein:
Function:
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. Together with HTL1, LDB7, RSC3, RSC30 components, defines a fungal-specific module within the RSC complex that plays a role in many cellular functions including the maintenance of cell wall integrity. Acidic protein important for nuclear protein localization.
Miscellaneous:
MISCELLANEOUS: Present with 3510 molecules/cell in log phase SD medium.
Subcellular Localization:
Nucleus.
Sequence:
MSDSEGGLASEVEHEKRSRSTSNRPNYAIDTEDLDIDENDENEDDDYREEEANEGVNEEEISDEEEQINKSGRNKRRHVDEEEDLSEDKGVTRSRNRSKFKKPVFPGIDDAEENLNPLKVVNEEYVLPDDPEGETKITADGDLLGGREFLVRTFTLTEKGNRKFMLATEPARIVGFRDSYLFFQTHPNLYKFILNQTQKNDLIDRGVLPYSYRNRQIALVTARGVFKEFGAKIIRGGKHITDDYYASELRTKGNVIEGKLAGDPIDKSARALETMMYPASENGINPAKNQVEFFEHRPHGHMSNSNIIASGSKLSSTNWLYQHSAACSRFNSDLFYDRVKVLLVDQQGLRDAYTNILHIPESTQSTTVLGWRRSKNDSPSDTSIVYETVIHDNDLNKPKTGLSEIPKEIYEDVVDEDVLRAITEQQNFEKCNEYI
The following text describes a protein:
Function:
Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida (By similarity).
Subcellular Localization:
Cytoplasm. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Note=Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis.
Sequence:
MSDSSKTNQCCPTPCCPPKPCCPPKPCCLQKSPCCPKSPCCPPKSPCCTPKVCPCPTPCPCPATCPAACACPCPMKPCCPTKCTCCPKKCTCCPQPTCCVQPTCCSSENKTESDSDGSGQTQDRGAQTQQSPQGGQGNWNQKKTK
The following text describes a protein:
Function:
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
Miscellaneous:
MISCELLANEOUS: Present with 300 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Sequence:
MGIVLKRAIAAGMKPFPNSTWHWSRTIRPFSQHLSSTCFLQQSSRFTSKRYLHLSTLTQQEKRFLPESELAKYKEYYQGLKSTVNEIPESVASKSPSLRTLHKRLQLPNELTYSTLSRCLTCPSAKLPDKINNPTKGAAFVNTVPTNKYLDNHGLNIMGKNLLSYHVTKSIIQKYPRLPTVVLNAAVNAYISEAVLAHIAKYWGIEVETTSVLSRYLKMEPFEFTLGRLKFFNNSLNSKDGIELITGKNFSETSALAMSVRSIIAAIWAVTEQKDSQAVYRFIDDHIMSRKLDITKMFQFEQPTRELAMLCRREGLEKPVSKLVAESGRLSKSPVFIVHVFSGEETLGEGYGSSLKEAKARAATDALMKWYCYEPLAQQEPVIDPGTVVV
The following text describes a protein:
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Subcellular Localization:
Plastid, chloroplast thylakoid lumen.
Sequence:
MIRCFAWTPLVGAPLITTVHFTSPPSLRIFASRSSAPSSSSSSSSTVAAASRRSISLSIIAVTSSVVSSFCFSSPALADFSEIPNSGGVKALDLRIGDGDVPIEGDQIEIHYYGRLAAKQGWRFDSTYDHKDSNGEAVPFTFVLGSSKVIPGIETAVRSMKVGGIRRVVIPPSQGYQNTSQEPLPPNFFDRQRLFTTIFNPTRLANGEGSTLGTLVFDIELVSTRRLHR
The following text describes a protein:
Function:
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
Sequence:
MARNPAAQTAFGPMVLAAVEQNEPPGRRLVDDDLADLFLPRPLRWLAGATRSAVLRRLLISASEWSGRGLWANLACRKRFIGDKLDEALGDIDAVVILGAGLDTRAYRLTRRVRMPVFEVDLPVNIARKAKTVRRVLGELPLSVRLVALDFEHDDLLTALAEHGYRTEYRVFFVCEGVTQYLTERAVRRTLEGLRAAAPGSRMVFTYVRRDFIDGTNRYGTRTLYHTVRQRRQLWHFGLDPEEVAGFLADYGWRLTEQAGPEELVQRYVEPTGRNLNASQIEWSAYAEKSEPVTPR
The following text describes a protein:
Function:
One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
Subcellular Localization:
Membrane; Single-pass membrane protein. Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Sequence:
MFVMLNILNLICICLNFALYSSSFFFTKLPEAYAFLNPIVDVMPVIPLFFFLLAFVWQAAVSFR
The following text describes a protein:
Function:
Mediates the transfer of lipids between membranes at organelle contact sites.
Subcellular Localization:
Membrane; Peripheral membrane protein.
Sequence:
MSTRIRFKMRASGVNLIVAQSQFKVEEFNGIILTTEKEIKISIGKLKVIDIEKKEEILESKEAKECINIKYKYGKNSMCRIEYNSPKLLLVPDVINRIWESLKEVIRHGINIFQEKEKKDIQILQKERLDNLKTPKIRNGTINQITQEKRINKENIINERYRLNIVFNLCKSQLIFKNNEGNSLLIYTTLEGNTLIENGRITSVNIVSSNLGIISKTLMRNEKIQIVNIKRFNITTKIGIVPIINLFIDSINTEFSNRDLETTIKLIKEFKENIESISLLFNKSIEINKKEINKEGFELQTNQIIKEENKSKSILFPKIIFNININNVEMILSSEFISQQGQTIESCKSLILSTKSFLMEFNEKQMEMCINKIQIQYTNISNKKWIIEPLIEPFDIKGKCILPKFQFEISPKKFLIINITPEFIISMNNLFENWAKSIDKEYYKNKGNCKIINRVGGTLTVQMKTKTITIEKDSTIEMALISEANIQIIINDFDPIIISTLINEKQYKTIYEVKKNEKTIGCILAKIYFYQKNQIIIISSIVIFKNKTSIPLQLIWNSFETNCFENQTSSFLPMIGINNLKFIIKSTKNHLKYKSFFINHSLYGKFIKNEYINIEHIDIDDFIDVHFHFHNSIQLGSTYITPLTIVFNSPLTFINNLPLKVLITCIKNENSFSSTSSVPLSHPSLCQTSKFIDLKESSNKTLSFNNHLTSSFSPSKIMQKTYINQKDLSSSSPLNFQNKCFNPSQSTQQQNPIISTSNTSLINSREKIQSIIVEPFSKGGITIASSNERIHYFITVLSVADGYTFNSNITKSSKTTYSINQKELPLLVIGSYYFRQRIQKNNIIFECPYYIKNDSQLPLLIKNYGEIQSIHSYYLYAPIPYKNEKNVFLMDNIIFIESNNKLSNEFIDLQLGETKTIHNNNHNLYTRVIPHKVNNQITSSLRIIIKPHFIFQNLTNEIFTIKNNNLNIKLFPDDKIPIHFTKITVEIVKNNGIDLDLTQIDEYQILLKTTNTYKIFNIKTQNHKGSFYTFISGCEQPFLRLDNRTNESFDVKQFGNKLTVKLIPQHSVPFAWTNPDGRRLLVINGVTIDPLNVDDEFVVNKRRVLIDIEDNTTVITVGASKRKKEQIQWSIGLSLSLFGISFFGKGAKEELSLNIKSILLEIVRTDRHIGLEMQFDYIQLDFQSLDILKNPVIISPRPLDWIYDPNKSFFHIGLLLITPTKGNLFQLRYISKATVTIQPLEVLIEPDILQHIFETLKEYPTLFMTENNNSASTTKNERRMIIKDFELNSIDVNISINKPTIKPSKYSKIVKLVYQIAEMDIDRIPIRINKLTIYNKRFSTNTFINQIKEKLMDDLGNLKWIVVGKLFGLRAIIGNSSDSINQEQTVFRITSMDGIDETTKHEFDLFFNRIYLTDSIDSKNLIATSLKTQDNIPRKDVPDSLVKAQQSTFEYSLKDGTKNLVSSVARGVKGVWKTSVGLTDLAGTQKKQLAPAGFIGGALVGAAGIVVKPLDGIVGFFKSVNDGLTGISFGQIAKERIRPPRYCPEQLICFDYLQSQGWSMLMEADGGAFKELKFYDWIKQVVDNKIKGIIFTFELMIGVEKEVGELTEFKWKIPYQLIESLGFDGNNIVIALKVSSKTKLFQRNNDRFVIKDWNIDYLVRINEIINSINTKK
The following text describes a protein:
Function:
Galactose-binding lectin. Agglutinates human erythrocytes, and requires Ca(2+) and Mn(2+) ions for full agglutinating activity. Has antifungal activity against Fusarium sp., A.niger and A.flavus.
Sequence:
AEETSFVFSKFKPLEPNLILQGDALVTVAGVLQLTNVDSNGVPEPSSLGRATYSAPINIWDSATGLVASFATSFRFTIYAPNIATIADGLAFFLAPVASAPDSGGGFLGLFDSAVGDTTYQTVAVEFDTYENTVFTDPPYTHIGFDVNSISSIKTVKWSLANGEAAKVLITYNSAVKLLVASLVYPSSKTSFILADIVDLSSVLPEWVRVGFSAATGASKGYIETHDVFSWSFASKLAG
The following text describes a protein:
Function:
Collagen VI acts as a cell-binding protein.
Subcellular Localization:
Secreted, extracellular space, extracellular matrix.
Sequence:
MLLILFLMMICLHVCANQDSGPEYADVVFLVDSSDHLGMKSFPLVKTFIQKLVSSLPVEANKYRVALAQYSDALHNEFHLGAFKNRNPMLNHLKKNFGFIGGSLKIGNALQEAHRTYFSAPTNGRDKKQFPPILVVLASAESEDDVEEASKALREDGVKIISVGVQKASEEDLKAMATSQFHFNLRTARDLSMFAPNMTQIIKDVTQYREAMTDDIIVEACQGPSVADVVFLLDMAINGSQENLDHLKAFLGESVSALDIKENCMRVGLVAYSNETRVISSLSMGVNKTEVLQRIQDLSPHVGQAYTGAALRKTRKEVFSAQRGSRKNQGVPQIAVLVTHRASDDNVTKAAVNLRREGVTVFTMGVEGANPEQLEKIASYPAEQFTSKLSNFSELATHNQTFLKKLRNQITHTVSVFSERTETLKSACVDTEEADIYLLIDGSGNTQPTDFHEMKIFLSEVVDMFNIAPHKVRVGAVQYADTWDLEFEISKYTNKPDLGKAIDNIRQMGGNTNTGAALNFTLTLLQRAKKQRGNKVPCHLVVLTNGMSQDSVLGPAHKLREENIRVHAIGVKEANQTQLREIAGDEKRVYYVHEFDALRDIRNQVVQEICAEEACRDMKADIMFLVDSSGSIGLENFSKMKVFMKNLVSKSQIGADRVQIGVVQFSHENREEFQLNTFMSQNDIANAIDQMAHIGETTLTGSALTFVSQYFSPEKGARPNVRKFLILITDGEAQDIVKDPAVALRKDGVIIYSVGVFGSNVTQLEEISGKPEMVFYVENFDILQHIEDDLVLGICSPREECKRIEVLDVVFVIDSSGSIDYQEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDELGTKLEVISVLQNDQPMGGNTYTAEALAFSDHMFTEARGSRLHKGVPQVLIVITDGESHDAEKLNATAKALRDKGILVLAVGIAGANTWELLAMAGSSDKYYFVETFGGLKGIFSDVSASVCNSSKVDCEIEKVDLVFLMDGSNSIHPDDFQKMKEFLASVVQDFDVSLNRVRIGVAQFSDSYRSEFLLGTFTGEKEISTQIEAIQQIFGYTHIGDALRKVKHYFRPDTGSRINAGTPQVLLVLTDGRSQDEVAQAAEELRHKGVDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVKKRIVRNICTSGGESNCFVDVVVGFDISSQRRGQTLLEGQPWMGTYLQDLLRAISSLNGVSCEVGTETQVSIAFQVTNAMERYPSKFEIYSENILSSLQGVTVNGPSRLNPNLLSSLWDTFQNKSAARGKVVLLFSDGLDDGVEKLEQKSDELRKEGLNALITIAVDGAADSSDLADLLYIEFGKGFEYRTQFTIGMGNLGSHLSKQLINVAERTCCCLLCKCTGWDGAMGDPGSAGEKGERGALGPMGEQGTKGCLGAKGPKGARGLSGEEGEVGEDGLDGLNGEQGDSGIPGRRGERGDAGSQGSPGKRGASGDRGPKGLRGDPGTPGRDNSIQGPKGLKGDPGRQGRRGWPGSPGTPGSRRKMVRVGSLSSQGNPGITGPDGLEGSPGLKGPQGPRGEVGEKGEKGGFGMKGPQGPPGPKGRAGNQGHWGSQGSKGEPGDLGEKGAAGFPGPRGLQGDDGSPGYGSIGWTCSICFCLTRHGEEKEGNGDIGDPGDPGEAGPKGARGKTVSAGIPGEPGSPGEPGPPGRKVRGMFFFFCLSGKPECPVHPTELVFVLDQSRDVTEQDFERMKGMMASLVRDIKVRDASCPVGARVAILAYNSHTRHLIRFSDAYRKDQLLREIKALPYEKSSDSREIGKAMRFISRNVFKRTLPGAHVRRIATFFSSGQSADVQSITTAAMEFSALDIIPVVIAFSNVPSVKRAFSIDDTGTFQVLVVPSRPDQVPALERLQRCTFCYDLCKPDASCDQAKPPIQSYLDAAFLLDSSWHVGGAEFEDMRDLLEALLDHFEIASEPETSVTGDRVALLSHAPVDFLPNTQRSPVRTEFNLTTYSSKHLMKRHVEQAVQQLNGDAFLGHALRWALDNVFLNTPNLRRNKVIFVISAGETSHLDAETLKKESLRAKCHGYALFVFSLGPDWDDKELEDLASHPLDQHLIQLGRIHKPDHGYGVKFVKSFINSIRHGINKYPPVNFKAKCSRLSSAAPKLSPRQFRSFVPGPQKALLKDHTLEAAKLFQDKKRLSSILRSGRAALSSHSRSTRYSFKQGREATKATSKLGKRSD
The following text describes a protein:
Function:
Controls the cellular levels and subcellular distribution of phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-bisphosphate. Involved in distinct membrane trafficking and signal transduction pathways. Highly active against a range of soluble and lipid inositol phosphates. Active in dephosphorylating the 5-position of Ins(1,4,5)P3 and Ins(1,3,4,5)P4 and to a lesser extent Ins(1,4,5,6)P4. The enzyme is also active against PI(4,5)P2 presented in sonicated vesicles and Triton mixed micelles, and somewhat less active against PI(3,5)P2 in unilamellar vesicles. Activity against PI(3,5)P2 drops sharply when this substrate is presented in mixed micelles. Also hydrolyzes PIP3 to produce PI(3,4)P2.
Subcellular Localization:
Cytoplasm. Note=Localizes at the cell tip and the barrier septum.
Sequence:
MQCLLREKPRSLALVNKDHALMFHSVPQNKNSLSVCVAEFTALSEKPLEGFRKISSHRIYGTLGLIELEGSNFLCVISGASEVARVRDKERVFRIMEVCFYSVNRSNWDHIRQENYSPDIPDGYDTDTQGYDSYKYAAEPFSSLRKLLTNGSFYFSLDFDITTRLQLRTSQTMTEPQYDSMHTQFMWNEFMLRQLIKFRSHLNGDEKSALDGCRFFTCAIRGFASTEQFKLGIQTIRLSLISRLSSLRAGTRFLSRGVDDDGNVANFVETETILDSSKYCVSYCQVRGSIPIFWEQEGVQMFGQKIDITRSLEATRAAFEKHFTSLIEEYGPVHIINLLGTGSGERSLSERLRQHIQLSPEKDLIHLTEFDYHSQIRSFEDANKIRPMIYSDAETFGFYFENNEGQSIVVQDGVFRTNCLDCLDRTNVIQNLVSRVFLEQVMIYTRQNAGYDFWQVHSTIWANNGDALARIYTGTGALKSSFTRKGKLSIAGALNDLSKSVGRMYINNFQDKGRQETIDLLLGRLIDQHPVILYDPIHEYVNHELRKRENEFSEHKNVKIFVASYNLNGCSATTKLENWLFPENTPLADIYVVGFQEIVQLTPQQVISADPAKRREWESCVKRLLNGKCTSGPGYVQLRSGQLVGTALMIFCKESCLPSIKNVEGTVKKTGLGGVSGNKGAVAIRFDYEDTGLCFITSHLAAGYTNYDERDHDYRTIASGLRFRRGRSIFNHDYVVWFGDFNYRISLTYEEVVPCIAQGKLSYLFEYDQLNKQMLTGKVFPFFSELPITFPPTYKFDIGTDIYDTSDKHRVPAWTDRILYRGELVPHSYQSVPLYYSDHRPIYATYEANIVKVDREKKKILFEELYNQRKQEVRDASQTSYTLIDIAGSVAGKPNLIPHLPANGVDKIKQPSSERSKWWFDDGLPAKSIAAPPGPEYRLNPSRPINPFEPTAEPDWISNTKQSFDKKSSLIDSIPALSPAPSSLARSSVSSQRSSTSIIPIKPNKPTKPDHLVAPRVKPLLPPRSGSSSSGVPAPNLTPVNVPPTPPPRKSSASQRSGDLLASSPEESSISWKPLV
The following text describes a protein:
Function:
May be involved in transcriptional regulation.
Subcellular Localization:
Nucleus.
Sequence:
MNCPASEMGEIITSQRSDSFPSPVQNKDQDVIRADALLKAIMSELIDSKFAVFQVKMDENGKEMANLRLRVEIAESELSALRGYILTSADKAAALRVPSSSRSRVGSPKRDLRTRRVLSAKSLAGKVASSTPAPQTGDSPPRATPNCQTEALWENHTPTCRGENRGIPAPRLETEKGLHAQEDTSREAAPKQEKKWIPFAKGNTFPQITRVQGNGDQGHRERCGEDQELVPCSVKEEDAEMDLNIIQVPVLESGSESGDELGVSQPVCEGDASPLDSAFFLGNGTAAGAMIPRKQQMGSPTAGCPRNSGVSQGDPRLDCVSGCDEMGRLVRELSCQDPMTQEGGPISLPAADGGAKVETEHCLEVPIKEALSDQHEQNLPPETGSSPHPVPAPFSRQPSPSASVPWNYGLQPYQPVPNVSALSLLPSMILPSGKYSGAGAGSQQPAEPTQCQADGGGNAGTTGMLRNLQHMYAGESFWRQDLNPSQHCNKPWTPGVAGASGEAYLCTECGRTFNLLGNLKAHQRLHAGDGRRRDLSAEDLDEHGNAQKPAYRCTECGRGFGHYRSLQRHWKTHTGERPYHCGECGKDFHLLESLKAHQRIHTGERPHVCAECGKRFSEVQNLRVHMRIHSGETPYPCAQCGKSFRQFQHLKRHRLVHAKPPLPLGARVGVHE
The following text describes a protein:
Function:
Bifunctional terpene synthase; part of the gene cluster that mediates the biosynthesis of conidiogenone, a diterpene known to induce the conidiation. The bifunctional terpene synthase PrDS converts isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) into deoxyconidiogenol. The C-terminal prenyltransferase (PT) domain of PrDS catalyzes formation of GGPP, whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GGPP into deoxyconidiogenol. The cytochrome P450 monooxygenase PrP450 then catalyzes two rounds of oxidation to furnish conidiogenone.
Domain:
The conserved DDXXD motifs as well as the NSE/DTE motif are important for the catalytic activity, presumably through binding to Mg(2+).
Sequence:
MGETIADVYAESIDPEIYANNPAYSSLFTPYIHKQTIIADHVSVQCHIDLNGIDAVGSKFGNLNAHAGNFTSLCAPNCLPERLALVAYTVEYAFLHDDETDNAADQEALLLENKMLHQAINQSSMTSVSNRVSAKAQRKSEVQAKIAAEYLRLDPVFGEFFLKAWQTFTASVQDVRSLEFPSLDDYLEFRIVDAAADWTLYNFRWGSGITLTPEEEKIADPMSYVAYAELCLVNDLFSWDKEYDAHVKSNGEVPLVNAVHIVAVTQGLTHCAAKAVVQAEIRAHEERFCYLKEQYKATASPSDSILSWLKLLEHSMAGNWVWSLCVPRYFKVERNPYKDHLEKFGSEAVRVLTPEEHLRDSKQEINGTKEIELQEPKSNNTAESDVLAKYTSGYPTIDEPVLNPYTYINSLPSKNVRQTMIAALNSWYKVPVKSLLIIEGAVNFLHNSSLLLDDIQDGSVLRRGRPVAHQIFGVGQTINTATYLMNEALYLVQMLSPSAVLVYTDEMRNLQLGQGRDLHWSYHTHVPTPAQYISMVDGKTGGLFRLISRLMRSEATVNRDLDISQFATLLGRHFQIRDDYQNLQSDDYTKNKGFCDDLDEGKLSFPIILSMQSPGFSNTALSSVFKGSQKGETLSPEMKQYILEEITARGAFSQTKAVLRKLHIELLRLLMETEQKAGGIENWALRLLIMKLDLGDEKKKEAHKSDSAWKVNQRRAWKGSQKNGRPIDKACFLRAMEEASQK
The following text describes a protein:
Function:
Transcriptional repressor required for the specification of numerous cell types during embryonic development. Required for terminal patterning of early embryos. May associate with gro to repress tll and hkb, restricting their expression to embryonic terminal poles where they initiate correct development of head and tail structures. Required for dorsoventral patterning of oocytes and early embryos. Cooperates with dl to repress zen and other dorsal specific genes within the embryo and promotes expression of the ventralizing factor pip in ovarian follicle cells. Required during wing development for the specification of intervein areas, where it mediates localized repression of vein specific genes such as aos, dpp and vvl.
Subcellular Localization:
Nucleus.
Sequence:
MNAFQDFELGAKLYLQCLLSLSSSRSATPSYTSPVNHAGASPLNAIAHSPVNVSATHRQNFFTPIANQSQQQQQQQPVAVPLDSKWKTTPSPVLYNANNNSSNNNTSSSNNNNNSNWEVGSNSNTHVAATAAATSTVGAQPLPPQTTPVSLVMHAPPPQQQPLQQQHHHHQPPPPPPASLPAPSAPPTSGSSSSHNSVGHATSVIRISSSQQQHQQQQQHQQQAHPHVVVSGGQTFHPVIVDATQLSVPLPPTTVSFHQPNTPTSTAASVASMSQDKMLAKNGYNAPWFKLLPHMTPMSKASPAPVTPTLTTSASSYNVVMMQQQQQHQQLQQQQQLQQQQQSPPQMPLNHNNNHLIVSAPLSSPGKPLNCSMNDAKVAAAAAAAAVANQRQKQQQEEPDDQLDDDVFETTTPGISANSKKQTAAMRLPTHNSNIRKLEECHDDGAAGAPATSAAKRRSQSLSALQQQQQQQQQAGAAGTAAGQPANKKIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCSKDRRKSSTSTATPGGKASGAAGTGDAKQRLVSVDGSDSLEHDMCPSTPGGSGSCGGQGISSDLQGDIIPLTIDNYNSTCDEAPTTISMKGNGNGKLMKNELPSDEDEQMLVVEEEQQQQTVKKIDLHCRERVNDSDMDDTPFDYRKQQPEANQRSAEEHSTSGANGQAINAPPLSGGEREITLKPKAIKAHPVLESNMLPYTQMSIYTQYTSPKNPIGVTPFQPTGGAFKSMPISPKGSGGKPEDAGSLQAHIKQEDIKQEPPSPYKLNNGSGSASGGGVVSAPPPNSGSVGAIFNFNVPTATALSQKQFHYPMHHPHRSPTDLRDEEADREEITQGTKSGESSEKDKPALDDQERDEVEEEDEDEEDDDEDDEDDEQFMQELASVNASAGFDDLVPYAMPKVVITPTPTPPPVATIVTPIKRKQFTIVRSLTPLQPSNSPHQQLKHLHQRRGETPPTVITRVPTPTINHFTIIRTQQHPHTHPHNTPPPLFFKQKVQGSPVIATVTTSTLSSSSSNPANNEAPNKFSNFPTQHQPTTTTTISCNTNNNATPIIRKLLTLQEGAELGGSHKGTGRAAILYDALVLDTLHGQDEEEEEDEGNAEKQENPKVAGKEQVTTSQPATMLLITDVNAYNQQHVAGNAATPVSGAATLRPVSFISINACNKITLPANARILTAATATSTAAGAAVTSQAGATLTVMTKASAATNHSSSNASDITITAASAAPVPTSGSSIVMINSTTNPSTSSNSTSCSAAAHQACVPSSPAGMGLGHAANIATPPASAPAQIMGGGPASQKMFFAMTHPYTLLQRSHQPGTPSLEHLQLDAFAPGGYTLRNHNGLSSLPPPVSAQPTMLLHGYPPSHGVEPPARSPSYKSMPSTPKSATYLMSAPPERGMDGGMSGCASAAASGGDESDIDADGQQFILAPTPAQLGRAPLQRRKNLSQSKSESNVSFGANLGASNGQHISRKLHSPTMMESSSPIIGHVNSSNLSSALPTPTSSTTTPNSDEQLPLTPTTSSSNSNLNQQQPKSPMKGAPGSTAAALKKKNDEMNNSVLKQVDFEKKYKALPQFQPEDCQSPSAIAVPSSPRVYGTNYRKKNTAPPPVQKLMCEDDSIDEPASAPPTTTQRFFGPDFNNELKELESSDQTGRSPRTPKTPLQSARSDASEKGHRKVLETRRSLVLQLFAEHGNFPTAQATMAFQSKHSDVFPRKQDLQLKIREVRQKLLGQASCTPHSAGPNTPSDSNSSSTTLSASSTSLNMQTTSAADVFQYY
The following text describes a protein:
Function:
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
Subcellular Localization:
Cytoplasm.
Sequence:
MTTAPAISSRLDDPESARETGRAKIDWAFEHMPILSALREEFDANQPLAGETIGMAMHVEAKTAALVETMADAGAEIAITGCNPLSTHDGVSAALDAHESITSYAERGAEGEAYYDAIDAVLAHEPTVTVDDGGDLVFRVHEDHPELIDTIIGGTEETTTGVHRLRAMDDDDALEYPVFAVNDTPMKRLFDNVHGTGESALANIAMTTNLSWAGKDVVVAGYGDCGRGVAKKAAGQNANVIVTEVEPRRALEAHMEGYDVMPMAEAAEVGDVFLTTTGNKNVITRAHFERMDDGVVLANAGHFDVEVNLDHLSELAVSEREAREGVREYELADGRRLNVLAEGRLVNLASPIGLGHPVGVMDQSFGVQAVCVRELVANREEYAAGVHNVPDELDIEIAEIKLAAEGVEYDALTDDQAEYMDSWQHGT