lhallee/plat_data huggingface dataset:
The following text describes a protein:
Function:
Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. Acting autonomously, serves itself as NLS receptor. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. In association with IPO7, mediates the nuclear import of H1 histone. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. Imports MRTFA, SNAI1 and PRKCI into the nucleus.
Subcellular Localization:
Cytoplasm. Nucleus envelope.
Sequence:
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIRLLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVSQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLSTCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGSILEGPEPNQLKPLVIQAMPTLIELMKDPSVVVRDTTAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLWKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAECQVCLAAVGLVGDLCRALQSNILPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDITLAIGGEFKKYLEVVLNTLQQASQAQVDKSDFDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA
The following text describes a protein:
Function:
Polycomb group (PcG) protein. Catalytic subunit of a the mes-2/mes-3/mes-6 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target genes. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. In association with the nfya-1-NF-Y complex, may play a role in repressing the expression of the homeobox protein egl-5 in tissues such as the head. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. The mes-2/mes-3/mes-6 complex may participate in the global inactivation of the X chromosomes in germline cells. This complex is required to exclude mes-4 from the inactivated X-chromosomes in germline cells. Required for small-RNA-induced H3K27 trimethylation. Involved in the negative regulation of lifespan in a germline-independent fashion.
Subcellular Localization:
Nucleus.
Sequence:
MSNSEPSTSTPSGKTKKRGKKCETSMGKSKKSKNLPRFVKIQPIFSSEKIKETVCEQGIEECKRMLKGHFNAIKDDYDIRVKDELDTDIKDWLKDASSSVNEYRRRLQENLGEGRTIAKFSFKNCEKYEENDYKVSDSTVTWIKPDRTEEGDLMKKFRAPCSRIEVGDISPPMIYWVPIEQSVATPDQLRLTHMPYFGDGIDDGNIYEHLIDMFPDGIHGFSDNWSYVNDWILYKLCRAALKDYQGSPDVFYYTLYRLWPNKSSQREFSSAFPVLCENFAEKGFDPSSLEPWKKTKIAEGAQNLRNPTCYACLAYTCAIHGFKAEIPIEFPNGEFYNAMLPLPNNPENDGKMCSGNCWKSVTMKEVSEVLVPDSEEILQKEVKIYFMKSRIAKMPIEDGALIVNIYVFNTYIPFCEFVKKYVDEDDEESKIRSCRDAYHLMMSMAENVSARRLKMGQPSNRLSIKDRVNNFRRNQLSQEKAKRKLRHDSLRIQALRDGLDAEKLIREDDMRDSQRNSEKVRMTAVTPITACRHAGPCNATAENCACRENGVCSYMCKCDINCSQRFPGCNCAAGQCYTKACQCYRANWECNPMTCNMCKCDAIDSNIIKCRNFGMTRMIQKRTYCGPSKIAGNGLFLLEPAEKDEFITEYTGERISDDEAERRGAIYDRYQCSYIFNIETGGAIDSYKIGNLARFANHDSKNPTCYARTMVVAGEHRIGFYAKRRLEISEELTFDYSYSGEHQIAFRMVQTKERSEKPSRPKSQKLSKPMTSE
The following text describes a protein:
Function:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular Localization:
Mitochondrion inner membrane.
Sequence:
MASPAARLLRAPRVPAAVLAASLAVSSADLAADDGAAPSSSVRPGRSPSGEKLPIYPTPQHNPAITLVETHNPLVPYITQSRESVSSVLGDARNYVQSGVSKWITFERSVEREVKSVLPPDEALNPGLIYVLVAGLSGSVLSRTRSLPVRFLAPPLFTLLAFPYFLPKTSHNIRQYLSNLEDKHLPEFAAKHDHFVQTGIAHWGMLWGRIEDATGDAREWGHRAVEGVERTTGLRLGEAVSKVEKEKERLVEQERQRAVAVPAQKYETVGYVVEQKPVAEIVAPMEPPKEKKLV
The following text describes a protein:
Function:
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Sequence:
MAGSDENNPGVIGPGNIQEGLRGRVGKFPVATGTNRRALSNINRNIIGGPPYPCAVNKRGLSEREAFCNKNPPIPVHRPLTRKYAAQLANKQQQQLEPEEIKKPVRPVPISSEPEDCNIIDVEGYKTSDDFSAPTFVQHTEAMLEEIDRMDEVEMEDVEEEPVLDIDGCDKRDPLAVVEYIDDLYNFYKKAERSGCVPPNYMAQQFDINDRMRGILIDWLIEVHYKFELMEETLYLTVNLIDRFLAVHPVVRKKLQLVGVTAMLLACKYEEVSVPVVEDLILISDKAYSRNEVLDMEKNMVNALQFNLSVPTPYVFMRRFLKASQCDRKQLELLAFFIIELCLVEYNMLKFPPSLLAAAAIYTAQCTLSGTKQWSKTNEWCTGYSEQQLTECSRLMVNFHRIAGTGKLTGVHRKYCTSKFGYAAKNEPADFLLDPPF
The following text describes a protein:
Function:
Catalyzes the hydrolysis of all eight canonical ribonucleoside triphosphates (NTP) and deoxyribonucleoside triphosphates (dNTP) to their corresponding nucleoside monophosphates ((d)NMP) and PPi and subsequently hydrolyzes the resultant PPi to Pi. The NTPase activity with deoxyribonucleoside triphosphates as substrate is higher than corresponding ribonucleoside triphosphates. dGTP is the best substrate among the deoxyribonucleoside triphosphates, and GTP is the best among the ribonucleoside triphosphates.
Sequence:
MKEAGILFEELVSIMEKLRSPEGCEWDRKQTHESLKPYLIEECYELIEAIDEKNDDMMKEELGDVLLQVVFHAQIARERGAFTIEDVIRTLNEKLIRRHPHVFGDSPGYSYKQWEDIKAQEKGKKKSSRIGEINPLVPALSMARRIQENASQVGFDWKDPEGVYEKIEEELKELKEAKDPRELEEEFGDLLFSIVNLSRFLNVDPESALRKATRKFVERFKKMEELIEKDGLVLEELPIEKLDEYWEKAKGGDET
The following text describes a protein:
Function:
Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.
Sequence:
MLERTSTCLESGGRKLLRTTKPCLRARRSLHSAFWHHGASDLSLPTWSAAPSAHESSNDSAESRAAKTPISTQSASPSGPLLDFLYPEKTLALLRQLSVPTIDATSPRRRCIHAPPVRHYATVPAHYEQPAVEEDAQALHKLREFLGHQKPGGQDEAWKLYSSIPAAHLAADGHWHLRADLLEYLAIDDDPPVPNRVLKLFEEIPEQHRRDSSYRAAIASYMSLRMVGPALQLLEDALSTQYELDYSVIGIDLVLRRTVLDEQWDLSLRVFSLYLEQKPTFTVSETPVTTWIRWGNTLPHIWKGVATLNRLDNHLRSFLLYLREFRYLFDPLEQEEHLPSPERPKEDKEKKRALLLFTMTFVPHTMDQVMQSSTWSEHGVAQFIRRLHKALVKLNFPMSVINEHTISRLLNVPSNRAVDQIPSLIAKVWGEHRQLCLDSRESSEEHKHKSSKPKLHTLRNLIIYYWRRDQFAQAHAVISDHHMFYPKEPMRAGLLKYMVHRFAEHGDFAQTEKYLEEFRRYYKDQTDVKLVSALAFACARRADVEGAIAQFHRIRDEFGLIPDTVCWNILILAYFRADDLDGALECFNTMVGNGIAADVYTFGTLLDACAQRGDVEAFEALYSRAEQTGVQLVQNLRVRSAYVEVFLQSGDVQAAEAVAQGLLKAWSAGTLSGNLTYTWNLLIQHCALERDIAGARARYREMIDHDIPLDSWTYGSLMRALVEVKQTNAAYKILRTTMPRNNLRIHALHYAIVMTGFLREGGEQLDLAVQVYQEMKKEKIPQTMSSQEATIRTLGMSQIKELQNTKKHANYKLKDVDEAVEEMLADALQGQAMYREPQHTRQMDTRNYGSGPQALYGLLISLYAQRGAYKTCMRLIKKAERLKPDVQNYTVPITLATGAMEVHFKAGEHAEVARMWELARTSARKLVNTFSEIAIQETPVPTSGDLLDASSIRESFEQSRIAPNRRNILYKATRVYMRSLFDSKNPNTEALQEAQRTMAELAAAGYTIDVFTWNELVTTLAQRGKISTAFAICEEYLMPNFPGWRSLHPNYIRKDRKGYRWMELRWDDIRPDSIMPRYKTLIVLAAQYRNVRRDERNAIGYDEEKGLWLREKLEEAAPMTLRAIQSMPSTNDKLQMEYFHDAL
The following text describes a protein:
Function:
Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides. By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow.
Subcellular Localization:
Membrane, caveola. Membrane; Multi-pass membrane protein.
Sequence:
MEDTKESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKALPENIKYGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKGPGISKYVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPYETNNQETFGALDLGGASTQITFVPQNQTTESPDNALQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTKRFEMTLPFQQFEIQGIGNYQQCHQSVLELFNTSYCPYSQCAFNGIFLPPLQGDFGAFSAFYFVMNFLNLTSEKVSQEKVTEMMKKFCSQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQPLSTPLSHSTYVFLMVLFSLVLVIVAIIGLLIFHKPSYFWKDMV
The following text describes a protein:
Function:
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
Sequence:
MDDYLPLAYLNAWEYCHRRFYLEYVLGEMEINEHIIRGNHLHRNINEAGTSVDGDTRIHRQQWVWSDRLKVKGIIDAVEESDGLLIPVEYKKGKMGKHLNDHFQLCAAALCLEEKTGKSITYGEIFYYGNRRRQPVEFTQALRNMTEQAIIAAHLACNGPMPRPIANTKKCADCSLERLCLPKELKKLTK
The following text describes a protein:
Function:
Silicon efflux transporter involved in silicon transport from the root cells to the apoplast. Is coupled with the silicon influx transporter NIP2-1/LSI1 in both exodermal and endodermal root cells for an efficient silicon transport across the cells into the stele. Silicon is beneficial to plant growth and helps plants to overcome abiotic and biotic stresses by preventing lodging (falling over) and increasing resistance to pests and diseases, as well as other stresses. In the nodes, involved with LSI3 and NIP2-2/LSI6 in silicon intervascular transfer, which is required for the preferential distribution of silicon, such as hyperaccumulation of silicon in the husk. Is coupled with NIP2-1/LSI1 transporter in roots for efficient uptake of arsenite, which is further dispatched in shoots and grains.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MSELASAPKVALGSIAFAVFWMMAVFPSVPFLPIGRTAGSLLSAVLMVIFHVISPDDAYASIDLPILGLLFATMVVGSYLRNAGMFKHLGRLLAWKSQGGRDLMCRVCVVTALASALFTNDTCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSAATPIGNPQNLVIAFNSKITFPKFLMGILPAMLVGMAVNMVMLLCMYWRELGGGAELSVDGKQMEAVEEGRSPASAKSTPQLNGNGNTMMSLEMSENITTKHPWFMQCTEARRKLFLKSFAYVVTVGMVVAYMVGLNMSWTAITTALALVVVDFRDAEPCLDTVSYSLLVFFSGMFITVSGFNKTGLPGAIWDFMAPYSKVNSVGGISVLSVIILLLSNLASNVPTVLLMGDEVAKAAALISPAAVTTSWLLLAWVSTVAGNLSLLGSAANLIVCEQARRAPRNAYDLTFWQHIVFGVPSTLIVTAVGIPLIGKI
The following text describes a protein:
Function:
Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro). May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase.
Subcellular Localization:
Nucleus.
Sequence:
MPRYCAAICCKNRRGRNNKERKLSFYPFPLHDKERLEKWLKNMKRDSWVPSKYQFLCSDHFTPDSLDIRWGIRYLKQTAIPTIFALPEDNQEKDPSKKKSQKKKLKSEKEVCLKAKSEESFASNEPKKHPVNTDLLPEHAELLESSALVKPPDPKAESVQNNILTLSLVKQGTRKPESILETSVNQDMGIGGFHTSFENLSSTTITLTTASSEGIQQPLETQEVIEITTNHLANPHFTNNSVEIKSAQENPFILSTVTQTVEELNTDKESVIAIFVPTENSKPAINSFIPAPKTVEMEEDIDIEDSYKDVDYETEVLQIEHSYCRQDVNKEHLWQKVSKLHSKITLLELQEQQTLGRLKSLEALIRQLKQENWLSEENVKIIENHFTTYEVTMI
The following text describes a protein:
Function:
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Sequence:
MSQVPVASPASWSSVASAAAAAVSAATSASSSLAASVDEPAATTATAATASYADERNPLIALFDGLLRVVLASLNLIRILATFSTITVPSLVYAILHYSLTLQLNFPSLALLFLTSLISAFIWLRYRHLNKYERLREVPITRDEGFNLNPDVASPGGDNDRGSFHNYLDDFLQAIRIFGFLEKPVFHELARHLQTRRLVAGDSLSLDTDFSFYIVIDGHVQVYAPLPSATASAVGQDSVEDEDDSGYQLLNEVESGGTLSSLFTILSLFTEDVKLSFDDHDDPHLAPPHPAYPAMDRLNNSSAANHLGRGNNATAPTSPYSSAFNPPSQTAAQLQLNAAALRNVPAAISTEGAVERLGGSAAVRSTSKSSHARTASSGTASATVQDGDTSTIMDPLEQNDDGVTSSLYHAPDLQMPPAQAAAPFSHFAPSYHPSPAGTPISSLPGSTHSPYFRGRATSIHALHEAAGGPNTPGSILSAMSSSAHGHYHPQADYLPRQGAGTVARATVDTTLAVIPAEAFKRLTKKFPNAAAHIVQVILARLSRVTFHTAHKYLGLTKEVMRTEKSINDLACFPLPSEFYEKGGMDKLRHRFLPQPNSKRETTVDDDYFRDFQEWTSISQRSSTPVPGSKDDTKDAATSSPPKVRIASDLPSLTTSSKQSNQKPTSSRISAARTPWGHPDPPLKTPTARNMVGPGDLLSMASLSQDGWYTTGFDMHSAQPTPRAKPRSVSKLEPFHGPLPHPVDDSTDGTSPLSGASPIPIRKGSSTMYHQGEAIGTDRPFANIGLPHFDIKNEVMDCIAKSIGLAQAAHSPLAPSYQASPHINAQDSLLQRSVFKSAFGSLSMLDAAMAEEESSITGTNSSMAGHGHSGFHPSDFENEVEIKFFPAGSTLVKAGESRAGLFYVIDGFLDVLLPAEANELEEEDRLKPNMNHKSAKTDASSGSSRQNRPGSHRKDSSSASLRAGLLDERNLREADVSLPQRRGTEADRISSNGDGNSGSVHRPAMREGSSSSTSYGTPAGLRKKPTESAKVGNALDGTGGAGSSSRRKPSHVSSGSGATTMPRHPDATNSNMAFTAKQPVLHPSLHQQQPLRGKPSQQSSQRSKDGKRSIFTVGRGGIAGYLSSLLGTASYVDITAKTDVYVGFLPAHALERIMERRPIVLLTLCKRLLSLLPPLILHIDSSLDWQQVNAGQVIYREDDPSDSFFIVINGRLRAITEKTNGIEVHNEYGQGDSVGELDVITNSRRRTTLHAIRDSELAKMPSTLFNAISVRHPAITIQISRIIARRVRTELVRSKQEGAALGAPIPGLPDLGRNNLNLKTVAIVPVTRQVPVIDFAAKLQTAFDDTIGGRAIFLDQSSVMGVLGRHAFSRMGKLKLAGWLADLEQKYRLVVYVVDTPVSSAWSQTSIRQADCVLMVGFGDEPAMGEYERLLMSVKTTARKELVLLHPERSVPPGSTREWLKNRPWVHAHHHVEMPGLTGSHAGAAISTGGDPKAVKALRNLKQKLETSLQRYRKTMTPLSASGRPHHASDFARLARRLCGMSIGLVLGGGGARGCAHLGVIRALEERGIPIDMVGGTSIGSLVGGLYAREAEMVSTFGRAKRFAGRMASLWRFASDLTYPVVSYTTGHEFNRGVFKAIQETHIEDMWIPFFCNTTNITWSRMEVHTSGYAWRYIRGSMTLAGLIPPLVDEGNMLVDGGYVDNLPVTVMLAMGARSVFAVDVGSIDDTSPRAYGDTLSGWWVLLNRWNPWSDASKIPSIPDIQGRLTYVSSVKTLEEAKKVKGCFYMRMPVEEFGTLAFGRFDMIYEKGYKAAVELLDGWDAEGKLPSGTEREDFEDDWEDGDEYEEYEVYTDDESGVGGGVRKIRKKRRRTRRKAGISARRNSI
The following text describes a protein:
Function:
May be involved in telomere capping.
Miscellaneous:
MISCELLANEOUS: Present with 1170 molecules/cell in log phase SD medium.
Subcellular Localization:
Mitochondrion.
Sequence:
MMGRNGIRLALKRSFSTYQPPVVEITNITKLWPTLRPEVRDEIKEYLRWRMQEDWRHIPLEETKAAYFLSYGPCGGRSKGNEWNVGYTGMRIVFNLVLFGGAATAFYNWKQDKKLEEQLRDLV
The following text describes a protein:
Function:
Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex. UAF seems to stimulate basal transcription to a fully activated level.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MEEYETDIKQILGTVDRQTVSAKQVRQLLEERRKVDLSAHKKDLNALILKCFDETAAPSEKESLEKQAPARKTKGKRATENGTEEGKKPAKRTRKRKEDGEEGGKRKRNQDPANNPLNKPMKLSPKLAEFLGLEQLSRPQTVKKLWEYIKAHDLQDPNDKRTILCDDKLKSVFEVDTLHMFTMNKYLTNLMTKIPDDQLPKPQPKNEEPAAPNDLPKQEEKELVEPPTAESTA
The following text describes a protein:
Function:
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLRLVMVVTIRFLYYFCFSVINFVIYFRICFLKCSKFLVCHHTLTIRRTSFLEIKGNIITGTADTVYSYGISLVIALIYCCNYCKRNCIIKALNKLHSVDLSLEKFGYTLPLVSVILMFVEYCNCNLYISPVLKSYTVFCNSVCGVEIILIMVEEYQFFMYLILLKQRFRAINTLLATNSEPINSHKIHTVLTTNCDKGMIVKLRSLHLQLCSAGKLLNEYFSIQILFLVALSFVGFTTNAYYSLDVIADNFANNERGVDIIPATLIWTVCRFIELVLISVICTATKNEVRATGELLYQVKDRFQSDIAVQLQLFGKQILHCDFKFTAFDFFDVDMTMFYGVIGSAATYLTILIQFEIAVKDYNKHSNTTSVP
The following text describes a protein:
Function:
Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. May regulate myosin assembly in striated muscles together with STUB1 and VCP/p97 by targeting myosin chaperone UNC45B for proteasomal degradation.
Subcellular Localization:
Cytoplasm. Nucleus.
Sequence:
MSWYKLIGWSNLVADQWKQYGTVEIQIRQKRLAKLGGAGNKPTGAGSKPASANSSPINTNIQPTGKSTSVSMSASVDAVGGLSDARSRFASAPTTPAVTTTPVATKSSTLAEIAVNTQSTALDNFLNLTNEDWLDRSLGSILQISLKTPAPNGLMYLQEVVDELKGESIPLVFTTDMIERVIYVRLQIPANSDPTMPALFDYLCGVWTRANSTRQTLKQFLALATENPTAASKACVCDTAIALLQSLAVNYAGLVLNPDMLDNFPLNHDWGSGFLGYKLLESHDPTSVYPREFITEFITRFEDDGLEDILGYTIKSVVTSMRTKSIIKQYIQPIRVFQYLVSFKPIANLVTQLSDWNPDFVNARTVEVMSILGPFLSRTGIFPDSDPEIAAKYFSSSNPFGEDMTDQRGNSIGARNNADVKTAMNGLRDASQLVHTDLFNIVIAIIKAGPTSRECVLAFISHVVKLNISRGKLQVDRRQVSTDGFMHNLLHVCLRLCDPIMDARFSKIALIDLNYPTYTTRLDFNDVTRILVDKDAVDVHVDQWKATHNSETNPQPPVNFVTDIFYLTLAMHHYGVLSTIRYYSGFIKELNEMRKQANKYKAVRDSGAWNLLQPFVRNANEEGLRRLQNEVDKLVGVKLTMDAGLMSPSALDYTLRLYNLTMMVLIRAASGMTETTCSVAWDQVACGNIDGVQLFPLPATPPIEFAVLPEWIIEDICEFYLFIMNNNPVILENRICDEIITFSMVFLSNPNYIRNPYLKSKLVEILFYFTIPLYRTSNGETRGRMDGVFSTHTLARAHLVRSTLGFYVDVEQTGMHSQFYDKFNIRYNISQIIKSVWTDPVHRTALVQASRDKDFFVKFVALLMNDTTYLLDEGLSKLKEIGGLQTELAVPLPENSSDEDKQRRKEREGLLAQHERQALSYVSLSNETVHMLQYMTSHSDIIEPFMATEIVERLAAMLDFNLVALAGPRCTELKVTNPEKYRFDPKRLLSDLVGIFVHLAHRTEFVAAVAKDGRSYSKEVFDRASSILSRHRLLNEMDIAKLNEFVGKVEQTLLADKIEEEEMGDVPDHFLDPLLYTLMEDPVILPSSGVTIDLSTIKSHLLSDAHDPFNRQPLSIDQVKPDVELKEQIQKWKQEKQTYRKTGNSPSMDTSL
The following text describes a protein:
Function:
This is an intracellular thiol proteinase inhibitor.
Subcellular Localization:
Cytoplasm.
Sequence:
MNQDTIVITGGLSEARPATPEIQEIADKVKTLLEEKTNGKYEKFEAIQYKVQVVAGRNYFIKMDVGHGCFTHIKVFQGLSGKDDLELSGYQTNKTKNDELTHF
The following text describes a protein:
Function:
Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate.
Sequence:
MISTTSLFAPVDQDLRLLTDNLKRLVGARHPILGAAAEHLFEAGGKRVRPAIVLLVSRATLLDQELTARHRRLAEITEMIHTASLVHDDVVDEADLRRNVPTVNSLFDNRVAVLAGDFLFAQSSWYLANLDNLEVVKLLSEVIRDFAEGEILQSINRFDTDTDLETYLEKSYFKTASLIANSAKAAGVLSDAPRDVCDHLYEYGKHLGLAFQIVDDILDFTSPTEVLGKPAGSDLISGNITAPALFAMEKYPLLGKLIEREFAQAGDLEQALELVEQGDGIRRSRELAANQAQLARQHLSVLEMSAPRESLLELVDYVLGRLH
The following text describes a protein:
Function:
Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis.
Subcellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Sequence:
MAQFPLFQKFQKAIQHPPALSLGLPIFLTVIFLLSQRYVWIEDDLELRSTALTNFELNRISFYPLVHATWFHLLLNLVALQPIVSQFERVNGTVRTGIVLNILAVVTAIPWCLLSIGFFPDEAVLGSSAWIFSFMGYWAIRESSKQPTTQLAPNLVVPTWLLPIIYLVVIAIVIPSSSFIGHLLGLIAGWMMALGYLDVLIEPSSKVVLWIENKISRVIDLIPSSIVTFYREEGALDTRAAARADTNRSLSVSGGNFLGFQANSSQADLEAGTRSRGNSSVDPTTSFPGTGQTLGTQ
The following text describes a protein:
Function:
Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released.
Subcellular Localization:
Plastid, chloroplast.
Sequence:
MGLPMARGPCCCSPSSSSSSSSPWMLQAQLPKNPHPPLSGRSVCSESLRVLALHLLLNRRANLSRRWGDITRTAASSSGLLQITGNMSGCSPKIKVDAERTSLDGALDRNAQFDMIYEDMSSWMNGAHTSGNSLQYNLLMQNIHVLQSSLAAQDLVLLERDILVHIEQLGALKWFNASRSGATITHTSHAPDFALPWNDTEFAPVTPLDEQSDDQLVIIRSGKSQERKLKRIRASEKVSVVCVKASSQKPRKSRRSTSSQFISEWKNYPGRRRSIVREQSDLLVTIKECANLEKIRENMVKEGQEVCYDKWAKAAGVDEAVLKSRLQAGYCCRERLLVTTEWLVKYIARTYTGMGTAFEDLLQAGKMGVLDGAERFDSQRGCKFSTYVKYWIRKPMLALLAENSGVIQLPARMDCIIRKVREAKRAIRSSTGRNPIDAEIATFVGASVANVRLARKCSRRVVSLYMEVGAGQNAKFMDVTPDTSLEDPEEAIFRRQLRERLLMVLDRLPAREGRVLKLRHGLEDGRCRSLEQIGGIYHVSKEWIRKIEKSAMSKLRNEDVHGELKDFCGF
The following text describes a protein:
Function:
Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis.
Subcellular Localization:
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane. Cell junction, focal adhesion. Secreted, extracellular space, extracellular matrix. Microsome membrane. Secreted. Synapse, synaptosome. Note=Proteolytic cleavage gives rise to a shedded ectodomain.
Sequence:
MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPPISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSLVNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSPFLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSILEMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT
The following text describes a protein:
Function:
Specifically methylates the N7 position of a guanine in 16S rRNA.
Subcellular Localization:
Cytoplasm.
Sequence:
MIRELFEKEGFTLDEEQERKFSIYLQELLRWNKVHNLTSIKKPEEIVRRHFIDSVSVVRCFERIGLDLRGKHFADVGSGAGFPGVPLKIYLKDIKLTLIESVSKKCSFLEYLKIKLNEDYRVLCTRAEKVEEKFDVVLARALGEFEEVKEILEKLSIGYVFVYKGSKLKEEWLKDYKLCELSLSFMPKSYILWKKV
The following text describes a protein:
Function:
Specific subunit of the TRAPP III complex that acts as an autophagy-specific guanine nucleotide exchange factor (GEF) for YPT1. TRS85 directs the TRAPP III complex to the phagophore assembly site (PAS) that is involved in autophagosome formation. Required for membrane expansion during autophagy and the CVT pathway. Required for sporulation. Has a role late in meiosis following DNA replication.
Miscellaneous:
MISCELLANEOUS: Present with 8760 molecules/cell in log phase SD medium.
Subcellular Localization:
Preautophagosomal structure.
Sequence:
MVFSYEHYMNLLFHLDNSKETVPPEIAKRIISNAIAPVITVTSTPLFDKHIQETYKVDSLYMLLRFFGGCVSDRDQANEAKVGQHEHEVCDASDSTDSIPKNKNLEVPNLSKKGSRSRSNSLFQRDSTQSQYIRFTRPLGDLIETRDANDMLFNYHSLEVFLDNYLKLVAANTDEMVPHNLLKKSIYHSFFSLAISSTNNLSPYETFNHPILSLIALDISNGEVYEDARDLLVNFKNLNHNTENFPIFMNTNEMLPVFLLCYNDDSQEEFEKCQALAKKLKKQLFVESILLALWKDSFIYDENSVIQLHQPVMSSLEEILFFLQAPTQTTLSLALINSIYDMLDYLVYDLMIPFMKRKVSFWEETILQPRKSLFNGAKFFKKFMNKNPVNGNHQHNSLTRDSQGNEYFASSSSEFLMRKLADWSMMLSDFKTAYSTYESLMDDLDAFPKYLASCIEWCAVSLLMGAQSIVTVKMIKNDINPLIERALATYENCSRIQRGKGKESNSLDVTEPVRSYETRCMILASELFLSLSNTWTSTPYAIQYLETILDECKLGPCSQIMVWERLSDCYNLRVDPRIKHRVGAMKKDAKDTEDLRGEHKYSTDHFTDEDILSEGLTRRRKAAFFRLIAAKKWAEQKQWRQVSWCLKDIESTYSEIKFLHGNGLILSKLKNQLNLKDVDSAPRPSEKNLTRTSVSFIG
The following text describes a protein:
Function:
Odorant receptor which plays a critical role in the anthropophilic host-seeking behavior; establishes the host preference to transmit malaria.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein.
Sequence:
MLIEECPIIGVNVRVWLFWSYLRRPRLSRFLVGCIPVAVLNVFQFLKLYSSWGDMSELIINGYFTVLYFNLVLRTSFLVINRRKFETFFEGVAAEYALLEKNDDIRPVLERYTRRGRMLSISNLWLGAFISACFVTYPLFVPGRGLPYGVTIPGVDVLATPTYQVVFVLQVYLTFPACCMYIPFTSFYATCTLFALVQIAALKQRLGRLGRHSGTMASTGHSAGTLFAELKECLKYHKQIIQYVHDLNSLVTHLCLLEFLSFGMMLCALLFLLSISNQLAQMIMIGSYIFMILSQMFAFYWHANEVLEQSLGIGDAIYNGAWPDFEEPIRKRLILIIARAQRPMVIKVGNVYPMTLEMFQKLLNVSYSYFTLLRRVYN